pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: CT-011 MAb in DLBCL Patients Following ASCT
Status: COMPLETED
Conditions: Lymphoma, Large Cell, Diffuse|Lymphoma, Mixed Cell, Diffuse|Primary Mediastinal Large B-Cell Lymphoma
Interventions: DRUG: CT-011
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Three Neonatal Antiretroviral Regimens for Prevention of Intrapartum HIV Transmission
Status: COMPLETED
Conditions: Disease Transmission, Vertical|Vertical Human Immunodeficiency Virus Transmission|HIV Infections
Interventions: DRUG: Zidovudine|DRUG: Nevirapine (NVP)|DRUG: Epivir (3TC)|DRUG: Nelfinavir (NFV)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Clinical Study of the Efficacy and Safety of the Application of Allogeneic Mesenchymal (Stromal) Cells of Bone Marrow, Cultured Under the Hypoxia in the Treatment of Patients With Severe Pulmonary Emphysema
Status: WITHDRAWN
Conditions: Pulmonary Emphysema
Interventions: BIOLOGICAL: Mesenchymal stem cells|OTHER: Reference therapy: 400 mL of 0.9% NaCl solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Seattle Cardiorenal Remote Ischemic Preconditioning Trial
Status: COMPLETED
Conditions: Congenital Heart Disease|Cardiopulmonary Bypass|Myocardial Injury|Acute Kidney Injury|Acute Lung Injury
Interventions: PROCEDURE: RIPC|PROCEDURE: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Impact of Extubation Location After Surgery on Perioperative Times
Status: COMPLETED
Conditions: Anesthesia|Intubation|Surgery|Extubation|Respiratory Failure|Complication,Postoperative
Interventions: PROCEDURE: Extubation in operative room|PROCEDURE: Extubation in post anesthesia care unit
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Objective Evaluation of Patients With Palmar Hyperhidrosis Submitted to Two Levels of Sympathectomy: T3 and T4.
Status: COMPLETED
Conditions: Hyperhidrosis|Quality of Life
Interventions: PROCEDURE: Video-assisted sympathectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Exploring the Effects of Corticosteroids on the Human Hippocampus
Status: RECRUITING
Conditions: Hydrocortisone|Depression|Healthy Volunteers
Interventions: DRUG: Hydrocortisone Oral|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Cerebral Microemboli in Venoarterial ECMO Patients
Status: COMPLETED
Conditions: Complication of Extracorporeal Membrane Oxygenation|Cerebral Microembolism|Cerebral Perfusion
Interventions: DEVICE: Transcranial Doppler Ultrasound
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phosphodiesterase-5-inhibitors for Right Heart Failure After Left Ventricular Assist Device Implantation
Status: COMPLETED
Conditions: Phosphodiesterase Inhibitor Adverse Reaction|Right-Sided Heart Failure
Interventions: OTHER: withdrawal of oral medication (phosphodiesterase-5 inhibitor) in pretreated patients
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: CAR- PRISM (PRecision Intervention Smoldering Myeloma)
Status: RECRUITING
Conditions: Multiple Myeloma|Smoldering Multiple Myeloma
Interventions: DRUG: Ciltacabtagene Autoleucel|DRUG: Cyclophosphamide|DRUG: Fludarabine Phosphate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevalence and Intervention of Hypomagnesemia in Users of Proton-pump Inhibitors
Status: COMPLETED
Conditions: Hypomagnesemia, Intestinal, With Secondary Hypocalcemia|Drug Induced Hypomagnesemia
Interventions: DIETARY_SUPPLEMENT: Inulin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Intrauterine Growth Hormone Administration as an add-on Therapy to Conventional Hormone Therapy Compared to Placebo in Patients With Thin Endometrium Undergoing Frozen Thawed Embryo Transfer
Status: ACTIVE_NOT_RECRUITING
Conditions: Thin Endometrium|Infertility Female|Infertility
Interventions: DRUG: Growh hormone|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Human-AI Collaborative Intelligence for Improving Fetal Flow Management
Status: RECRUITING
Conditions: Healthy
Interventions: BEHAVIORAL: "XAI feedback on MCA/UA Doppler spectral curves and gate placement suggestions"
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Assessment of Non-Fasting vs. Fasting Lipid Measures in Diabetes Patients
Status: COMPLETED
Conditions: Diabetes Mellitus|Normal Glucose Metabolism|Hyperlipidemia
Interventions: OTHER: fasting 12+ hours|OTHER: Non-fasting
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Advair Pediatric Once-Daily
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: FP 100mcg|DRUG: FSC 100/50mcg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of E2609 in Subjects With Mild Cognitive Impairment or Mild Dementia Due to Alzheimer's Disease (Study: E2609-A001-101 Amendment 02)
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: E2609|DRUG: Placebo for E2609
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Olanzapine Versus Lithium in the Treatment of Acute Depression in Patients With Bipolar II or Bipolar Not Otherwise Specified(OL Study)
Status: COMPLETED
Conditions: Bipolar Disorder
Interventions: DRUG: olanzapine|DRUG: lithium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Azacitidine and Entinostat in Treating Patients With Advanced Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Male Breast Carcinoma|Recurrent Breast Carcinoma|Stage IIIC Breast Cancer AJCC v7|Stage IV Breast Cancer AJCC v6 and v7|Triple-Negative Breast Carcinoma
Interventions: DRUG: Azacitidine|DRUG: Entinostat|OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacological Study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation and Rehabilitation for Coordinated Control of Bilateral Ankle Joints in Stroke Patients
Status: UNKNOWN
Conditions: Stroke，Rehabilitation，Coordination，Ankle
Interventions: DEVICE: Bilateral ankle coordination training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rituximab and Pegylated Interferon α-2b in Patients With Indolent B-cell Lymphoma
Status: UNKNOWN
Conditions: Lymphoma, B-Cell
Interventions: DRUG: Rituximab Biosimilar|DRUG: Pegylated Interferon α-2b
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Shock Waves for Treatment of Gynoid Lipodystrophy and Localized Fat
Status: COMPLETED
Conditions: Lipodystrophy|Cellulitis|Adiposity
Interventions: DEVICE: THORK Shock Wave® (Extracorporeal shock waves)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Local Anlagesia Into the Trocar Site During Operative Laparosocpy
Status: UNKNOWN
Conditions: Pain
Interventions: DRUG: bupivacain 0.5%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: High Dose Cyclophosphamide, Tacrolimus, and Mycophenolate Mofetil in Preventing Graft Versus Host Disease in Patients With Hematological Malignancies Undergoing Myeloablative or Reduced Intensity Donor Stem Cell Transplant
Status: COMPLETED
Conditions: Acute Leukemia|Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma|Chronic Myelogenous Leukemia, BCR-ABL1 Positive|Diffuse Large B-Cell Lymphoma|Follicular Lymphoma|Graft Versus Host Disease|Hodgkin Lymphoma|Mantle Cell Lymphoma|Marginal Zone Lymphoma|Myelodysplastic Syndrome|Myeloproliferative Neoplasm|Recurrent Acute Myeloid Leukemia With Myelodysplasia-Related Changes|Recurrent Plasma Cell Myeloma|Refractory Plasma Cell Myeloma|Secondary Myelodysplastic Syndrome
Interventions: DRUG: Busulfan|DRUG: Cyclophosphamide|DRUG: Fludarabine Phosphate|PROCEDURE: Hematopoietic Cell Transplantation|OTHER: Laboratory Biomarker Analysis|DRUG: Melphalan Hydrochloride|DRUG: Mycophenolate Mofetil|PROCEDURE: Peripheral Blood Stem Cell Transplantation|OTHER: Quality-of-Life Assessment|DRUG: Tacrolimus|RADIATION: Total-Body Irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study on Sequential Immunization of Inactivated SARS-CoV-2 Vaccine and Recombinant SARS-CoV-2 Vaccine (Ad5 Vector)
Status: COMPLETED
Conditions: COVID-19
Interventions: BIOLOGICAL: Recombinant SARS-CoV-2 Ad5 vectored vaccine|BIOLOGICAL: Inactive SARS-CoV-2 vaccine (Vero cell)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Perioperative Pain and Delirium in Geriatric Patients With Hip Fracture
Status: UNKNOWN
Conditions: Delirium|Delirium in Old Age|Hip Fractures|Dementia|Pain|Analgesia|Mental Status Change
Interventions: OTHER: fascia iliaca compartment block with ropivacaine|OTHER: fascia iliaca compartment block with placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Lens Fitting Evaluation of CooperVision MyDay™ Compared With 1-DAY ACUVUE® TruEye® and DAILIES TOTAL1®
Status: COMPLETED
Conditions: Myopia
Interventions: DEVICE: stenfilcon A|DEVICE: delefilcon A|DEVICE: narafilcon A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: A Feasibility Trial of Geriatric Assessment and Management for Older Cancer Patients
Status: COMPLETED
Conditions: Breast Cancer|Gastrointestinal Cancer|Genitourinary Cancer
Interventions: PROCEDURE: GA and Integrated Care Plan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effectiveness of Screening and Decolonization of S. Aureus to Prevent S. Aureus Surgical Site Infections in Surgery Outpatients
Status: RECRUITING
Conditions: Staphylococcus Aureus Colonization|Surgical Site Infections|Healthcare Associated Infections
Interventions: OTHER: Screening and decolonization for SA carriers with the 3 drug bundle|OTHER: No screening for SA|OTHER: no screening|OTHER: Nasal povidone-iodine on surgery day plus 2 CHG pre-op showers without screening.|OTHER: Nasal alcohol gel on surgery day plus 2 CHG pre-op showers without screening
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: BGB324 in Combination With Pembrolizumab or Dabrafenib/Trametinib in Metastatic Melanoma
Status: COMPLETED
Conditions: Melanoma
Interventions: DRUG: BGB324+pembrolizumab|DRUG: BGB324+dabrafenib and trametinib|DRUG: pembrolizumab|DRUG: dabrafenib and trametinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Active Video Game on Cardiorespiratory, Macro and Microcirculation Function of Adolescents With Overweight
Status: COMPLETED
Conditions: Overweight and Obesity|Cardiovascular Risk Factor|Physical Activity
Interventions: OTHER: Active video game
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Acellular Matrix From Human Dermis in Combination With Orthobiologic Stimuli for Augmentation of Massive Rotator Cuff Tears
Status: RECRUITING
Conditions: Rotator Cuff Tears
Interventions: OTHER: Acellular Dermal Matrix|OTHER: Acellular Dermal Matrix with autologous orthobiologics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Mandala Coloring Activity on Stress and Anxiety in Mothers With Babies in NICU
Status: NOT_YET_RECRUITING
Conditions: Anxiety|Parents|Psychological Stress
Interventions: OTHER: Mandala coloring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of RoActemra/Actemra (Tocilizumab) in Combination With Methotrexate in Patients With Active Rheumatoid Arthritis Who Have an Inadequate Response to Non-biologic DMARDs
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: tocilizumab [RoActemra/Actemra]|DRUG: methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PGE1 Improves Coronary Microcirculation Dysfunction in Patients With CAD and Diabetes
Status: UNKNOWN
Conditions: Coronary Microvascular Perfusion in Patients With Ischemic Heart Disease
Interventions: DRUG: Lipo-PGE1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EUS-FNB With MOSE vs EUS-FNA With ROSE
Status: RECRUITING
Conditions: Pancreatic Neoplasms
Interventions: DIAGNOSTIC_TEST: MOSE|DIAGNOSTIC_TEST: ROSE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Steroid Withdrawal in Pediatric Renal Transplant: Impact on Growth, Bone Metabolism and Acute Rejection
Status: COMPLETED
Conditions: Kidney Diseases
Interventions: DRUG: Tacrolimus (TAC)+ Mycophenolate Mofetil (MMF) + Withdrawal Prednisone|DRUG: Tacrolimus (TAC)+ Mycophenolate Mofetil (MMF) + prednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bariatric Surgery on obesity-and Diabetes-associated Abnormalities of Hemostasis, Inflammation and Vascular Function.
Status: COMPLETED
Conditions: Surgery|Obesity Associated Disorder|Coagulation Disorder|Diabetes Complications
Interventions: PROCEDURE: Laparoscopic Roux-en-y gastric bypass
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of Two Analgesic Pretreatment Techniques Before Spinal Needle Insertion for Pain Reduction and Maternal Satisfaction Level Assessment in Women Undergoing LSCS.
Status: COMPLETED
Conditions: Anesthesia, Spinal|Pain|Pregnancy|Cesarean Section
Interventions: DRUG: EMLA cream|DRUG: 2% lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: 99mTc-DARPinG3 SPECT/CT for Non-invasive HER2-AX in Breast Cancer With Metastatic Lymph Nodes Before Targeted Therapy
Status: COMPLETED
Conditions: Breast Cancer Female
Interventions: DRUG: 99mTc-DARPinG3 SPECT/CT
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of KD6005 in Healthy Participants and Participants With Rheumatoid Arthritis (RA)
Status: RECRUITING
Conditions: Rheumatoid Arthritis
Interventions: DRUG: KD6005|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Dilated Blood Vessels on the Cheeks With a New Yellow Laser and a Traditional Green Laser
Status: COMPLETED
Conditions: Telangiectasia|Rosacea
Interventions: DEVICE: PHOTOLASE|DEVICE: KTP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Early Mobilization of Knee Joint After ACL Surgery. Continuous Passive Motion Versus Manual Passive Mobilization
Status: COMPLETED
Conditions: Anterior Cruciate Ligament Reconstruction
Interventions: DEVICE: CPM|OTHER: Manual mobilization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Cases of Cutaneous Leishmaniasis Treated With Miltefosine in French Guiana, Retrospective Study
Status: UNKNOWN
Conditions: Cutaneous Leishmaniases|Treatment Adherence|Primary Health Care|Drug Evaluation
Interventions: OTHER: Data collection|OTHER: Questionnaires
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Post-Market Surveillance of Tobacco Products
Status: COMPLETED
Conditions: Smoking, Tobacco|Smoking Behaviors
Interventions: OTHER: Moist Snuff|OTHER: Camel Snus|OTHER: Cigarettes|OTHER: No tobacco usage
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study Comparing 3 Formulations to Evaluate the Efficacy and Safety of the Inflammatory Symptoms of the Upper Respiratory Tract, in Children Between 2 and 6 Years Old
Status: WITHDRAWN
Conditions: Common Cold
Interventions: DRUG: Bronpheniramine and fenilefrine (Decongex Plus)|DRUG: Bronpheniramine isolated|DRUG: Fenilefrine isolated
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: TESS V3 Modular Total Shoulder System PMCF
Status: ACTIVE_NOT_RECRUITING
Conditions: Osteoarthritis Shoulder|Rheumatoid Arthritis|Rheumatoid Arthritis Shoulder|Avascular Necrosis|Revision|Rotator Cuff Tears|Osteonecrosis|Rotator Cuff Tear Arthropathy|Proximal Humeral Fracture|Malunion of Fracture, Shoulder Region
Interventions: DEVICE: Anatomic TESS V3|DEVICE: Reverse TESS V3
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Broader Efficacy of Atomoxetine in the Treatment of ADHD in Children/Adolescents
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: DRUG: Atomoxetine Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Project to Identify Biomarkers of Morbidity and Mortality in Cardiovascular Interventional Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Atrial Fibrillation|Coronary Artery Disease|Aortic Valve Stenosis|Aortic Valve Disease|Mitral Valve Disease|Cardiac Arrythmias|Cardiac Tumor|Cardiac Surgery
Interventions: PROCEDURE: Cardiac surgery
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Biomechanical Evaluation of a Novel, Compliant Low Profile Prosthetic Foot
Status: COMPLETED
Conditions: Amputation
Interventions: DEVICE: Layered Low Profile Foot|DEVICE: Prescribed Ankle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Realtime Diagnosis From Electrocardiogram Artificial Intelligence-Guided Screening for Atrial Fibrillation With Long Follow-Up (REGAL)
Status: ENROLLING_BY_INVITATION
Conditions: Atrial Fibrillation
Interventions: OTHER: Apple Watch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: 7-day Atorvastatin and Emotional Processing
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Atorvastatin 20mg|OTHER: Lactose placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Benefit of Local Anesthesia at the Sternum in Patients With Coronary Surgery
Status: COMPLETED
Conditions: Coronary Bypass Graft Stenosis
Interventions: DRUG: Ropivacaine|DRUG: sodium chloride 0.9%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy Study of Bimatoprost in Ethnically Japanese Patients With Open-Angle Glaucoma or Ocular Hypertension
Status: COMPLETED
Conditions: Glaucoma|Ocular Hypertension
Interventions: DRUG: Bimatoprost 0.01% Ophthalmic Solution|DRUG: Bimatoprost 0.03% Ophthalmic Solution|DRUG: Bimatoprost Vehicle Ophthalmic Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Efficacy of XTL 2125 in HCV-Infected Patients Who Are Interferon-Alpha Non-Responders or Relapsers
Status: WITHDRAWN
Conditions: Chronic Hepatitis C Virus Infection
Interventions: DRUG: XTL-2125
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Interest of Pan Capsule in Symptomatic Patients Suspected of Irritable Bowel Syndrome Requiring Colonoscopy
Status: COMPLETED
Conditions: Irritable Bowel Syndrome With Diarrhea
Interventions: OTHER: Pan Capsule and colonoscopy in patients with IBS
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Short-term Effects of Ventilation Tubes in Children With Chronic Otitis Media With Effusion
Status: COMPLETED
Conditions: Otitis Media With Effusion in Children|Quality of Life|Sleep
Interventions: DEVICE: Tympanostomy tube insertion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Chen's U-Suture Technique for Pancreaticojejunostomy Following Pancreaticoduodenectomy
Status: UNKNOWN
Conditions: Pancreaticoduodenectomy
Interventions: PROCEDURE: Chen's U-Suture|PROCEDURE: Classic pancreatic duct to mucosa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Food Study of Oxybutynin Chloride ER Tablets 10 mg and Ditropan XL® Tablets 10 mg
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Oxybutynin Chloride ER Tablets 10 mg|DRUG: Ditropan XL® Tablets 10 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Increasing Engagement With Messages Regarding CRC Screening Among Adults Aged 45-49
Status: COMPLETED
Conditions: Colorectal Cancer|Colorectal Neoplasms
Interventions: BEHAVIORAL: Risk Information|BEHAVIORAL: Risk Information + Action
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Brief Behavioral Therapy for Insomnia (bBT-I) for Depressed Outpatients With Refractory Insomnia
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: BEHAVIORAL: brief behavioral therapy for insomnia (bBT-I)|OTHER: Treatment as usual (TAU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Association Between Side Effects Occurrence and Concentrations of Ibrutinib and Idelalisib
Status: COMPLETED
Conditions: Hematological Malignancies
Interventions: OTHER: Blood samples for pharmacokinetics exploration|OTHER: Imagery|OTHER: Quality of life scale|OTHER: Detection of adverse events|GENETIC: Saliva samples|GENETIC: Blood sample|OTHER: Biological statement|OTHER: Clinical examination
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Immunogenicity and Safety Study of a Booster Dose (5th) of Diphteria-Tetanus-Pertussis-Polio Vaccine
Status: COMPLETED
Conditions: Diphtheria|Tetanus|Pertussis|Polio
Interventions: DRUG: Boostrix polio
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Young Adult Congenital Heart Disease Physical Activity Lifestyle Study (YACHD-PALS)
Status: COMPLETED
Conditions: Cardiovascular Disease Other|Physical Activity
Interventions: BEHAVIORAL: Physical Activity Lifestyle Intervention|BEHAVIORAL: Physical Activity Monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Interventional Study of Vosoritide for the Treatment of Children With Hypochondroplasia
Status: ENROLLING_BY_INVITATION
Conditions: Hypochondroplasia
Interventions: DRUG: Vosoritide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Respiratory-gated Auricular Vagal Afferent Nerve Stimulation (RAVANS) Study in Ulcerative Colitis
Status: RECRUITING
Conditions: Ulcerative Colitis
Interventions: DEVICE: RAVANS|DEVICE: RAVANS-sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: A Clinical Trial of TQC2938 Injection in Healthy Adult Subjects
Status: ACTIVE_NOT_RECRUITING
Conditions: Asthma
Interventions: DRUG: TQC2938 Injection|DRUG: TQC2938 Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Safety Study of Anti-hypertension Combination Drug in Patients Uncontrolled With Monotherapy.
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Amosartan® tab|DRUG: Cozaar® plus pro tab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transcranial Direct Current Stimulation and Dual Tasks
Status: RECRUITING
Conditions: Parkinson Disease
Interventions: DEVICE: Transcranial Direct Current Stimulation|PROCEDURE: Dual task
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Single Center Study of Donafenib Combined With PD-1 + TACE in the First-line Treatment of aHCC
Status: COMPLETED
Conditions: Donafenib
Interventions: DRUG: Donafenib, PD-1|PROCEDURE: TACE
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Contact-CTI Study: Use of Tissue Contact Data to Guide Atrial Flutter Ablation
Status: COMPLETED
Conditions: Atrial Flutter
Interventions: PROCEDURE: Radiofrequency ablation utilising the ECI contact software|PROCEDURE: Radiofrequency ablation without the use of ECI contact data
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Multi-Component Intervention to Improve Health Outcomes and Quality of Life Among Rural Older Adults Living With HIV
Status: COMPLETED
Conditions: HIV
Interventions: BEHAVIORAL: Group-Based Social Support|BEHAVIORAL: HIV Stigma Reduction|BEHAVIORAL: Strengths-Based Case Management (SBCM)|BEHAVIORAL: Personalized Technology Detailing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PDT With Metvix® 160 mg/g Cream in Organ Transplant Recipients With Non-melanoma Skin Cancer
Status: COMPLETED
Conditions: Actinic Keratosis|Warts|Basal Cell Carcinoma|Bowens Disease|Squamous Cell Carcinoma
Interventions: PROCEDURE: Photodynamic therapy with Metvix 160 mg/g cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparison Erect Spine in Cardiac Surgery
Status: UNKNOWN
Conditions: Spine Erector|Cardiac Surgery|Acute Pain|Chronic Pain
Interventions: DRUG: Ropivacaine 0.2% Injectable Solution|DRUG: Ropivacaine 0.2% + Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Walk On! Physical Activity Coaching
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: BEHAVIORAL: Physical Activity Coaching (Walk On!)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Bortezomib With or Without Irinotecan in Treating Patients With Locally Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck
Status: COMPLETED
Conditions: Recurrent Squamous Cell Carcinoma of the Hypopharynx|Recurrent Squamous Cell Carcinoma of the Larynx|Recurrent Squamous Cell Carcinoma of the Lip and Oral Cavity|Recurrent Squamous Cell Carcinoma of the Nasopharynx|Recurrent Squamous Cell Carcinoma of the Oropharynx|Recurrent Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity|Recurrent Verrucous Carcinoma of the Larynx|Recurrent Verrucous Carcinoma of the Oral Cavity|Stage IV Squamous Cell Carcinoma of the Hypopharynx|Stage IV Squamous Cell Carcinoma of the Larynx|Stage IV Squamous Cell Carcinoma of the Nasopharynx|Stage IV Verrucous Carcinoma of the Larynx|Stage IVA Squamous Cell Carcinoma of the Lip and Oral Cavity|Stage IVA Squamous Cell Carcinoma of the Oropharynx|Stage IVA Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity|Stage IVA Verrucous Carcinoma of the Oral Cavity|Stage IVB Squamous Cell Carcinoma of the Lip and Oral Cavity|Stage IVB Squamous Cell Carcinoma of the Oropharynx|Stage IVB Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity|Stage IVB Verrucous Carcinoma of the Oral Cavity|Stage IVC Squamous Cell Carcinoma of the Lip and Oral Cavity|Stage IVC Squamous Cell Carcinoma of the Oropharynx|Stage IVC Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity|Stage IVC Verrucous Carcinoma of the Oral Cavity|Tongue Cancer
Interventions: DRUG: bortezomib|DRUG: irinotecan hydrochloride|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Crossover Bioequivalence Study of Quetiapine Fumarate 300 mg Tablets Under Steady State Fasted Conditions
Status: COMPLETED
Conditions: Bipolar I Disorder
Interventions: DRUG: Quetiapine Fumarate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MRI Study of Noninvasive Transcranial Electrical Stimulation in Tinnitus
Status: COMPLETED
Conditions: Tinnitus, Subjective
Interventions: DEVICE: Transcranial electrical stimulation (tES)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Octohydroaminoacridine Succinate Tablet for Mild-to-Moderate Alzheimer's Disease
Status: UNKNOWN
Conditions: Alzheimer Disease
Interventions: DRUG: Octohydroaminoacridine Succinate|DRUG: Aricept|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Preoperative Chemoradiotherapy for Locally Advanced Resectable Gastric Adenocarcinoma
Status: UNKNOWN
Conditions: Gastric Adenocarcinoma
Interventions: DRUG: TS-1 + cisplatin|RADIATION: radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation Of Clostridium Difficile Vaccine Lot Consistency In Healthy Adults 65 To 85 Years Of Age
Status: COMPLETED
Conditions: Clostridium Difficile Associated Disease
Interventions: BIOLOGICAL: Clostridium difficile vaccine|BIOLOGICAL: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Impact of Chemotherapy on Urinary Biomarkers and Non-Invasive Urodynamics in Children
Status: RECRUITING
Conditions: Survivors of Childhood Cancer|Bladder Dysfunction
Interventions: DIAGNOSTIC_TEST: Non-invasive Urodynamic Test (niUDS)|DIAGNOSTIC_TEST: Urinary proteomic screen|OTHER: Dysfunctional Voiding Symptom Score Survey (DVSS)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Hyperglycaemia on Local Energy Stores in the Working Muscle in Patients With Type 1 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1|Exercise
Interventions: PROCEDURE: Normoinsulinemic eu- or hyperglycemic clamp
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE|Primary Purpose:
Clinical trial: Preoperative Misoprostol in Reducing Blood Loss in Total Abdominal Hysterectomy (TAH)
Status: COMPLETED
Conditions: Hysterectomy
Interventions: DRUG: Misoprostol|DRUG: Vitamin B 6
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of the Mu-Drop System for Serum Eye Drops
Status: UNKNOWN
Conditions: Dry Eye Syndrome
Interventions: OTHER: Allogeneic conventional sized serum eye drops|OTHER: Allogeneic micro sized serum eye drops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Non-invasive Assessment to Predict Tolerance to Fluid Removal on Intermittent Kidney Replacement Therapy
Status: RECRUITING
Conditions: Acute Kidney Injury|Chronic Kidney Disease Stage 5 on Dialysis|Chronic Kidney Failure|Intradialytic Hypotension|Fluid Overload
Interventions: DIAGNOSTIC_TEST: Estimated absolute blood volume|DIAGNOSTIC_TEST: Modified VExUS evaluation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Efficacy of Tianeptine Versus Pregabalin on Acute and Chronic Post Mastectomy Pain After Breast Cancer Surgery.
Status: RECRUITING
Conditions: Post-mastectomy Pain Syndrome
Interventions: DRUG: Pregabalin|DRUG: Tianeptine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pilot Study on Pairing Sedation Strategies and Weaning
Status: COMPLETED
Conditions: Acute Respiratory Failure
Interventions: DRUG: Sedation Protocol with Daily Interruption|DRUG: Sedation Protocol Without Daily Interruption|DRUG: Fentanyl Push First
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimization and Improvement of Care Course for 75 Years and Over Patient With Cancer and Living in Nursing Home on the Marseille Agglomeration
Status: UNKNOWN
Conditions: Cancer|Elderly
Interventions: OTHER: personalised care plan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Tolerability of Pharmaton Capsules in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Pharmaton® with DMAE|DRUG: Pharmaton® without DMAE|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Effect of Oligopin® on Skin Ageing
Status: COMPLETED
Conditions: Skin Aging
Interventions: DIETARY_SUPPLEMENT: Oligopin|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of Extended Release (ER) Niacin/Laropiprant When Added to Ongoing Lipid-Modifying Therapy in Patients With High Cholesterol or Abnormal Lipid Levels (MK-0524A-133)
Status: TERMINATED
Conditions: Primary Hypercholesterolemia|Mixed Dyslipidemia
Interventions: DRUG: Extended-release niacin/laropiprant (ERN/LRPT)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Molecular Imaging With Erlotinib and Bevacizumab
Status: COMPLETED
Conditions: Non-Small-Cell Lung Carcinoma
Interventions: DRUG: Erlotinib, Bevacizumab|DRUG: Fluoro-D-glucose|DRUG: Fluoro-L-thymidine|DRUG: Gadolinium-DPTA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Different Lining Strategies on Amalgam Restorations
Status: UNKNOWN
Conditions: Post-operative Pain|Dental Caries
Interventions: PROCEDURE: No lining|PROCEDURE: Calcium Hydroxide cement|PROCEDURE: RMGI cement|PROCEDURE: Resin Bonding Agent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of EarlySense for Monitoring Ovulation Cycles and Detection of Early Stages of Pregnancy in Home Environment
Status: ACTIVE_NOT_RECRUITING
Conditions: Reproduction
Interventions: DEVICE: EarlySense home device|PROCEDURE: Vaginal ultrasound|PROCEDURE: Blood Test
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effects of Hypertonic Saline-HES Solution on Extracellular Water in Cardiac Surgery Patients
Status: COMPLETED
Conditions: Fluid Volume Disorder
Interventions: DRUG: 7.2% NaCl/hydroxyethylstarch|DRUG: NaCl 0.9%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ultrasound-Guided Intermediate Cervical Plexus or Cervical Erector Spinae Block for Anterior Cervical Spine Surgery
Status: COMPLETED
Conditions: Analgesia
Interventions: PROCEDURE: intermediate cervical plexus block|PROCEDURE: Cervical Erector spinae block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Traditional Chinese Medicine Pediatric Massage for Attention Deficit Hyperactivity Disorder Symptoms
Status: UNKNOWN
Conditions: ADHD
Interventions: OTHER: Parent-administered TCM pediatric massage training|OTHER: Progressive Muscle Relaxation Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Airway Intubation Devices When Using a Biohazard Suit
Status: COMPLETED
Conditions: Intubation; Difficult
Interventions: OTHER: standard clothing|OTHER: Biohazard gear|DEVICE: Direct Laryngoscopy|DEVICE: Glidescope|DEVICE: Supraglottic Airway
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Randomized Controlled Trial of Alert-Based Computerized Decision Support for Optimizing Low-Density Lipoprotein Management
Status: ACTIVE_NOT_RECRUITING
Conditions: Hyperlipemia, Mixed|ASCVD
Interventions: BEHAVIORAL: Alert
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treating Mild Traumatic Brain Injury With High Definition Transcranial Direct Current Stimulation
Status: RECRUITING
Conditions: Traumatic Brain Injury
Interventions: DEVICE: Transcranial direct current stimulation|DEVICE: sham tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Atomoxetine Hydrochloride Versus Placebo in Taiwanese Children and Adolescents With ADHD
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: DRUG: Atomoxetine Hydrochloride|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Delayed or Direct Ureteroscopy in the Treatment of Pediatric Calcular Anuria
Status: UNKNOWN
Conditions: Acute Renal Failure|Anuria|Obstructive Uropathy|Ureteric Stones
Interventions: PROCEDURE: initial urinary drainage|PROCEDURE: direct ureteroscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating the Efficacy of 5-FU + NALIRI and 5-FU + NALIRINOX for PDAC (NALPAC)
Status: RECRUITING
Conditions: Metastatic Pancreatic Ductal Adenocarcinoma
Interventions: DRUG: Nanoliposomal irinotecan|DRUG: 5 FU|DRUG: Leucovorin|DRUG: Oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Aims to Collect Information in Routine Clinical Practice in Italy About the Number of Patients Suffering From Irregularly Heart Beats Which Are Not Caused by a Heart Valve Problem (Non-valvular Atrial Fibrillation, NVAF) Who Stopped or Changed Rivaroxaban Treatment
Status: COMPLETED
Conditions: Non-valvular Atrial Fibrillation
Interventions: DRUG: Rivaroxaban (Xarelto, BAY59-7939)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of the Safety and Efficacy of Nabiximols Oromucosal Spray Versus Placebo in Patients With Post-traumatic Stress Disorder
Status: WITHDRAWN
Conditions: Post-Traumatic Stress Disorder
Interventions: DRUG: Nabiximols|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ruxolitinib for Adult T-Cell Leukemia
Status: TERMINATED
Conditions: T Cell Leukemia, Adult|Leukemia, Adult T-Cell|T Cell Leukemia, HTLV I Associated
Interventions: DRUG: Ruxolitinib|DRUG: Ruxolitinib|DRUG: Ruxolitinib|DRUG: Ruxolitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Oral Everolimus in Patients With Neovascular Age-related Macular Degeneration
Status: TERMINATED
Conditions: Choroidal Neo-Vascular Age-onset Macular Degeneration|Age-related Macular Degeneration
Interventions: DRUG: Everolimus|DRUG: Ranibizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Belimumab Treatment of Emphysema Patients With Anti-GRP78 Autoantibodies
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease|Emphysema
Interventions: BIOLOGICAL: Belimumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Safety and Efficacy of Phentolamine Mesylate Ophthalmic Solution in Subjects With Severe Night Vision Disturbances
Status: COMPLETED
Conditions: Night Vision Complaints|Decrease in Night Vision|Disturbance; Vision, Loss
Interventions: DRUG: Phentolamine Mesylate Ophthalmic Solution 1.0%|DRUG: Phentolamine Mesylate Ophthalmic Solution 0.5%|OTHER: Phentolamine Mesylate Ophthalmic Solution Vehicle (Placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Romanian National Registry of Outcomes After Transcatheter Aortic Valve Implantation in Patients With Severe Aortic Stenosis - RO-TAVI
Status: UNKNOWN
Conditions: Aortic Stenosis Symptomatic|Aortic Valve Stenosis
Interventions: DEVICE: Transcatheter Aortic Valve Implantation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Targeting Human Milk Fortification to Improve Preterm Infant Growth and Brain Development
Status: RECRUITING
Conditions: Preterm Birth|Breast Milk Expression|Nutrition Disorder, Infant|Brain Development Abnormality|Neurodevelopmental Disorders
Interventions: OTHER: Individually targeted fortification
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Bio ACL Reconstruction Amnion Collagen Matrix Wrap and Stem Cells
Status: ACTIVE_NOT_RECRUITING
Conditions: ACL - Anterior Cruciate Ligament Rupture
Interventions: OTHER: Bio ACL|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Short Cycle Therapy in ART Regimens Containing Rilpivirine: Assessment of Patients' Satisfaction
Status: COMPLETED
Conditions: HIV-1-infection
Interventions: OTHER: HIV Treatment Satisfaction Questionnaire status
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH