pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: AMENO-2: Aprepitant Plus Palonosetron Versus Granisetron in the Prevention of Nausea and the Emesis Induced by Chemotherapy in Patients Treated With Haematopoietic Progenitors
Status: COMPLETED
Conditions: Leukemia|Lymphoma
Interventions: DRUG: Aprepitant|DRUG: Palonosetron|DRUG: Granisetron
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety & Feasibility Study of Tack-It Device for Vessel Dissection Repair
Status: COMPLETED
Conditions: Critical Limb Ischemia|Peripheral Artery Disease
Interventions: DEVICE: Innovasc Tack Intravascular Staple System (Tack)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aspirin and a PoTent P2Y12 Inhibitor Versus Aspirin and Clopidogrel in Patients Undergoing PCI for Complex Lesion
Status: RECRUITING
Conditions: Coronary Artery Disease
Interventions: DRUG: Dual antiplatelet therapy with a P2Y12 inhibitor plus aspirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Designing Optimal Prevention and Management of Postoperative Nausea and Emesis for Patients Undergoing Laparoscopic Sleeve Gastrectomy
Status: COMPLETED
Conditions: Post-operative Nausea and Vomiting|Laparoscopic Sleeve Gastrectomy
Interventions: DRUG: Aprepitant 80 mg Oral Capsule|DRUG: scopolamine transdermal|PROCEDURE: Total intravenous anesthesia|DRUG: Dexamethasone|DRUG: Ondansetron|DRUG: Reglan|DRUG: Ondansetron|DRUG: Compazine|DRUG: Sugammadex|DRUG: Propofol|DRUG: dexmedetomidine|DRUG: Fentanyl|DRUG: Sevoflurane|DRUG: Desflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Delivering Transcutaneous Auricular Neurostimulation to Improve Relapse Prevention in Opioid Use Disorder
Status: RECRUITING
Conditions: Opioid-use Disorder|Opioid Withdrawal
Interventions: DEVICE: Sparrow Ascent Therapy System|DRUG: Lofexidine|DRUG: Extended-release injectable naltrexone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Treatment of Tumors in the Urinary Collecting System of the Kidney or Ureter Using a Light Activated Drug (WST11)
Status: ACTIVE_NOT_RECRUITING
Conditions: Upper Tract Urothelial Carcinoma
Interventions: DRUG: WST11 mediated vascular targeted phototherapy (VTP)|PROCEDURE: Endoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Liver Transplant for Stable, Advanced Intrahepatic Cholangiocarcinoma
Status: ENROLLING_BY_INVITATION
Conditions: Cholangiocarcinoma, Intrahepatic
Interventions: PROCEDURE: Liver Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity of HPV Vaccine in Immunosuppressed Children
Status: COMPLETED
Conditions: Autoimmune Disease|Juvenile Idiopathic Arthritis|Inflammatory Bowel Disease|Evidence of Liver Transplantation|Kidney Transplant Infection|Bone Marrow Transplant Infection
Interventions: BIOLOGICAL: Quadrivalent HPV vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: tDCS + CCFES-mediated Functional Task Practice for Post-stroke Upper Extremity Hemiplegia
Status: RECRUITING
Conditions: Stroke|Upper Extremity Paresis|Hemiplegia
Interventions: DEVICE: Active conventional tDCS montage plus CCFES|DEVICE: Active unconventional tDCS montage plus CCFES|DEVICE: Sham tDCS plus CCFES|BEHAVIORAL: CCFES with Occupational Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Esomeprazole Magnesium With or Without Aspirin in Preventing Esophageal Cancer in Patients With Barrett Esophagus
Status: COMPLETED
Conditions: Barrett Esophagus|Esophageal Cancer
Interventions: DRUG: acetylsalicylic acid|DRUG: esomeprazole magnesium|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Rubus Occidentalis Extract on Plasma Glucose Levels in Subject With Prediabetes
Status: COMPLETED
Conditions: Prediabetes (Impaired Fasting Glucose and/or Impaired Glucose Tolerance)
Interventions: DRUG: Rubus occidentalis extract
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dulaglutide Versus Liraglutide in Obese Type 2 Diabetic Adolescents Using Metformin
Status: COMPLETED
Conditions: Type 2 Diabetes Treated With Insulin|Obesity|Adolescent Obesity
Interventions: DRUG: Dulaglutide|DRUG: Liraglutide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pathophysiological Mechanisms of Dyspnea and Activity-limitation in Mild Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DEVICE: Dead space breathing|DEVICE: Room air breathing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Efficacy of NF-kB Inhibition for Reducing Symptoms During Maintenance Therapy in Multiple Myeloma Patients
Status: WITHDRAWN
Conditions: Multiple Myeloma
Interventions: DRUG: Curcumin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Immune Response of BMS-936559 in HIV-Infected People Taking Combination Antiretroviral Therapy
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: BMS-936559|DRUG: Placebo for BMS-936559
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Method Antimetabolites Application on Corneal Function in Trabeculectomy Surgery
Status: UNKNOWN
Conditions: Glaucoma Patients Scheduled for Trabeculectomy
Interventions: DRUG: Mitomycin_c|DRUG: Mitomycin_c
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Losartan Compared to Losartan/HCTZ in Pediatric Patients With Hypertension (0954A-327)
Status: TERMINATED
Conditions: Hypertension
Interventions: DRUG: hydrochlorothiazide (+) losartan potassium|DRUG: losartan potassium|DRUG: Placebo for Losartan|DRUG: Placebo for Losartan/HCTZ
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Bioequivalence Study of the Fixed Dose Combination Tablets of Canagliflozin and Metformin Extended Release (XR) With Respect to the Individual Components in Healthy Fed Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Canagliflozin, 100 mg|DRUG: Metformin XR, 500 mg|DRUG: CANA/MET XR FDC, Formulation 1, 50 mg/1000 mg|DRUG: CANA/MET XR FDC, Formulation 2, 50 mg/1000 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PET Imaging Tau Accumulation in FTLD and Atypical Alzheimer's Using PI-2620
Status: RECRUITING
Conditions: Frontotemporal Lobar Degeneration|Alzheimer Disease|Cognitively Normal
Interventions: DRUG: FPI-2620
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Physical Activity in Patients With Systemic Lupus Erythematosus
Status: UNKNOWN
Conditions: Systemic Lupus Erythematosus
Interventions: OTHER: Physical Activity: Cardio training (CT)|OTHER: Physical Activity: Endurance exercise training (ET)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: AZD6244 Hydrogen Sulfate for Children With Nervous System Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Neurofibromatosis 1|Neurofibromatosis Type 1|NF1|Neurofibroma, Plexiform
Interventions: DRUG: AZD6244
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study Testing the Effects of Chemical Peels in Patients With Rosacea
Status: WITHDRAWN
Conditions: Rosacea
Interventions: DRUG: 15% Trichloroacetic acid peel|DRUG: 30% Salicylic acid peel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety and Pharmacokinetics of ALMB-0166 in Patients With Acute Spinal Cord Injury
Status: UNKNOWN
Conditions: Acute Spinal Cord Injury
Interventions: DRUG: ALMB-0166
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intensity Modulated Radiotherapy (IMRT) for the Pelvis Post-Hysterectomy
Status: COMPLETED
Conditions: Uterine Cancer|Cervical Cancer|Endometrial Cancer
Interventions: RADIATION: Intensity Modulated Radiotherapy (IMRT)|PROCEDURE: CT Scan
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Dallas Heart Study 2: Return Clinic Visit for the Dallas Heart Study Cohort
Status: COMPLETED
Conditions: Atherosclerosis|Congestive Heart Failure|Left Ventricular Hypertrophy|Diabetes Mellitus|Hypertension|Obesity|Metabolic Syndrome X|Myocardial Infarction
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Femoral Nerve Block vs Peri-capsular Nerve Group Block for Hip Fracture Analgesia
Status: COMPLETED
Conditions: Spinal Anesthesia|Analgesia|Hip Fractures
Interventions: OTHER: femoral nerve block|OTHER: peri-capsular nerve group block
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Non-Invasive Magnetic Resonance Imaging (MRI) and Magnetic Resonance Spectroscopy Techniques (MRS) for Assessing Neoadjuvant Chemotherapy in Locally Advanced Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: PROCEDURE: Magnetic Resonance Imaging (MRI)|PROCEDURE: Magnetic Resonance Spectroscopy (MRS)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of Avastin (Bevacizumab) in Combination With Platinum-Based Chemotherapy in Patients With Advanced or Recurrent Squamous Non-Small Cell Lung Cancer
Status: TERMINATED
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: bevacizumab [Avastin]|DRUG: Platinum-based chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess Safety and Effect of a Prebiotic Fiber Meal Replacement Shake in Individuals With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DIETARY_SUPPLEMENT: Supergut|DIETARY_SUPPLEMENT: Placebo|OTHER: Dietary guidelines
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Study Of Sumatriptan Succinate Injection Kit In Patients With Migraine or Cluster Headache In Japan
Status: COMPLETED
Conditions: Migraine Disorders
Interventions: DRUG: Sumatriptan Succinate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 16-Week Randomized Split-Face Efficacy Study of Cosmetic Formulations in Photoaged Pigmented Skin Subjects
Status: UNKNOWN
Conditions: Aging Problems|Pigmentation
Interventions: OTHER: Cosmetic Formulations
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Relative Energy Deficiency in Sport Multicenter Study
Status: UNKNOWN
Conditions: Health, Subjective|Nutrition Disorders|Athletic Injuries|Hormone Disturbance|Exercise-related Amenorrhea|Eating Disorders|Sleep Hygiene|Cardiovascular Abnormalities|Bone Fracture|Bone Loss|Weight Change, Body|Mental Health Wellness 1
Interventions: BEHAVIORAL: Treatment of REDS using a holistic treatment arm
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: A Safety Surveillance Study in Subjects With Macular Degenerative Disease Treated With Human Embryonic Stem Cell-derived Retinal Pigment Epithelial Cell Therapy
Status: ENROLLING_BY_INVITATION
Conditions: Macular Degenerative Disease
Interventions: BIOLOGICAL: Human Embryonic Stem Cell-Derived Retinal Pigment Epithelial Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial Investigating the Exposure of NN5401 in Young Adults and Elderly Subjects With Type 1 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 1
Interventions: DRUG: insulin degludec/insulin aspart|DRUG: biphasic insulin aspart 30
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Highly Selective CDK7 Inhibitor Q901 in Selected Advanced Solid Tumors
Status: RECRUITING
Conditions: Advanced Cancer|Metastatic Cancer
Interventions: DRUG: Q901|DRUG: KEYTRUDA® (pembrolizumab)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lower Urinary Tract Symptoms and School Functioning in Children
Status: RECRUITING
Conditions: Lower Urinary Tract Symptoms|Neurodevelopmental Disorders|Incontinence, Urinary|ADHD|ASD|Developmental Coordination Disorder|Child Development|Quality of Life
Interventions: OTHER: Questionnaire Welbevinden|OTHER: Questionnaire Vancouver symptom score for dysfunctional elimination syndrome|OTHER: Developmental Coordination Disorder Questionnaire|OTHER: Questionnaire concerning LUTS, NDDs and treatment perceptions|OTHER: Questionnaire about policies and practices regarding children's toilet use and drinking habits in the classroom
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of Individualized Radiotherapy Based on a Prediction Model of Lymph Node Metastasis in Hepatocellular Carcinoma
Status: UNKNOWN
Conditions: Lymph Node Metastasis|Hepatocellular Carcinoma|Radiotherapy
Interventions: RADIATION: Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: ADH-1, Gemcitabine Hydrochloride & Cisplatin in Treating Metastatic Pancreatic or Biliary Tract Cancer
Status: COMPLETED
Conditions: Ampulla of Vater Adenocarcinoma|Gallbladder Adenocarcinoma|Metastatic Pancreatic Adenocarcinoma|Pancreatic Adenocarcinoma|Stage III Ampulla of Vater Cancer|Stage III Intrahepatic Cholangiocarcinoma|Stage III Pancreatic Cancer|Stage IIIA Gallbladder Cancer|Stage IIIA Hilar Cholangiocarcinoma|Stage IIIB Gallbladder Cancer|Stage IIIB Hilar Cholangiocarcinoma|Stage IV Ampulla of Vater Cancer|Stage IVA Gallbladder Cancer|Stage IVA Hilar Cholangiocarcinoma|Stage IVA Intrahepatic Cholangiocarcinoma|Stage IVA Pancreatic Cancer|Stage IVB Gallbladder Cancer|Stage IVB Hilar Cholangiocarcinoma|Stage IVB Intrahepatic Cholangiocarcinoma|Stage IVB Pancreatic Cancer
Interventions: DRUG: ADH-1|DRUG: Cisplatin|DRUG: Gemcitabine Hydrochloride|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: National, Multicenter, Retrospective, Prospective Study to Evaluate Pediatric Gastrointestinal Eosinophilic Disorders
Status: RECRUITING
Conditions: Eosinophilic Gastrointestinal Disorders|Eosinophilic Esophagitis|Eosinophilic Gastritis or Gastroenteritis|Eosinophilic Colitis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Safety and Efficacy of Embotrap in Treating Acute Ischemic Stroke Patients
Status: RECRUITING
Conditions: Stroke|Acute Ischemic Stroke
Interventions: DEVICE: Embotrap stent retriever|DEVICE: Solitaire FR, Trevo stent retriever without inner channel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Food Containing Resistant Starch Type 4 and Postprandial Glycemic Response
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Cereal Bar no fiber|DIETARY_SUPPLEMENT: Cereal bar with 10 g fiber|DIETARY_SUPPLEMENT: Cereal bar with 20 g fiber
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of Cebranopadol for the Treatment of Acute Pain After Bunionectomy
Status: NOT_YET_RECRUITING
Conditions: Acute Pain
Interventions: DRUG: Cebranopadol|DRUG: Oxycodone IR|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Learning Implementation of Guideline-based Decision Support System for Hypertension Treatment: Testing Alternative Antihypertensive Regimens Using ACE-Inhibitors, Calcium Channel Blockers and Diuretics (LIGHT-ACD)
Status: UNKNOWN
Conditions: Hypertension
Interventions: BEHAVIORAL: Protocol initiate with A|BEHAVIORAL: Protocol initiate with C|BEHAVIORAL: Protocol initiate with D
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dietary Fish Oil Intervention in Polycystic Ovary Syndrome (PCOS)
Status: SUSPENDED
Conditions: Polycystic Ovary Syndrome|Lipid Metabolism Disorders
Interventions: DRUG: Metformin|COMBINATION_PRODUCT: Fish Oil and Metformin|DIETARY_SUPPLEMENT: Fish Oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effects of Simulated Equestrian Therapy on Motor Proficiency and Gait Parameters Among Down Syndrome Children
Status: COMPLETED
Conditions: Down Syndrome
Interventions: DEVICE: Simulated Equestrian Therapy|OTHER: Neuro-Motor Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Erlotinib or Placebo Following Chemoradiotherapy (Chemo/RT) in Stage III Non-Small Cell Lung Cancer (NSCLC)
Status: COMPLETED
Conditions: Carcinoma, Non-Small-Cell Lung|Non-small Cell Lung Cancer|NSCLC
Interventions: DRUG: Erlotinib (tarceva)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Drug Interaction Study of Montelukast and Levocetirizine
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Levocetirizine|DRUG: montelukast sodium|DRUG: Montelukast & levocetirizine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Shoulder Functional Outcomes of Patients With Proximal Humerus Fractures: Comparison of Two Different Treatment Protocol
Status: UNKNOWN
Conditions: Humeral Fracture
Interventions: OTHER: Scapula mobilization|OTHER: Shoulder ROM exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Tirzepatide (LY3298176) Versus Placebo in Participants With Type 2 Diabetes Inadequately Controlled on Insulin Glargine With or Without Metformin
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: Tirzepatide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, Pharmacokinetics (PK) of the Anti-Orthopox Drug, ST-246
Status: COMPLETED
Conditions: Orthopoxviral Disease
Interventions: DRUG: ST-246 400 mg|DRUG: ST-246 600 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: 1a/1b Study of OPT101 First in Human Study Assessing Safety and Tolerability of 15-mer Peptide.
Status: RECRUITING
Conditions: Healthy
Interventions: DRUG: OPT101
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Digoxin and Senolysis in Heart Failure and Diabetes Mellitus
Status: NOT_YET_RECRUITING
Conditions: Heart Failure, Systolic|Diabetes Mellitus, Type 2
Interventions: DRUG: Digoxin 0.125 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Post-market Registry to Assess the Clinical Performance and Safety of the Passeo-18 Lux in Infrainguinal Arteries
Status: UNKNOWN
Conditions: Angioplasty, Balloon|Disease, Peripheral Artery
Interventions: DEVICE: Passeo-18 Lux Paclitaxel releasing Balloon Catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial of Pimozide in Patients With Amyotrophic Lateral Sclerosis (ALS)
Status: UNKNOWN
Conditions: ALS|Amyotrophic Lateral Sclerosis
Interventions: DRUG: Pimozide 2mg/day (current) or 4 mg/day (study initiation)|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Stepped Care Intervention to Reduce Disparities in Mental Health Services Among Cancer Patients and Caregivers
Status: COMPLETED
Conditions: Cancer, Lung|Cancer, Head and Neck
Interventions: BEHAVIORAL: Stepped-Care Intervention|BEHAVIORAL: Enhanced Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: SECOTEX® (Tamsulosin Hydrochloride) Bioequivalence Study Brazil - Fed Admin
Status: COMPLETED
Conditions: Prostatic Hyperplasia
Interventions: DRUG: Reference formulation|DRUG: Test formulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study of Nifurtimox to Treat Refractory or Relapsed Neuroblastoma or Medulloblastoma
Status: COMPLETED
Conditions: Neuroblastoma|Medulloblastoma
Interventions: DRUG: Nifurtimox|DRUG: Cyclophosphamide|DRUG: Topotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Memantine add-on for Cognitive and Negative Symptoms of Schizophrenia
Status: UNKNOWN
Conditions: Schizophrenia
Interventions: DRUG: Memantine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Magnesium Supplementation and Blood Pressure Reduction
Status: ACTIVE_NOT_RECRUITING
Conditions: Blood Pressure
Interventions: DIETARY_SUPPLEMENT: magnesium glycinate supplement|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Better Understand Motor Deficits Associated With Autism Spectrum Disorders: Development of an Assessment Protocol
Status: RECRUITING
Conditions: Autism Spectrum Disorder
Interventions: BEHAVIORAL: Testing of general motor skills, fine motor skills and occulomotricity|BEHAVIORAL: Questionnaires
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Combination of Baricitinib and Anti-TNF in Rheumatoid Arthritis
Status: RECRUITING
Conditions: Rheumatoid Arthritis
Interventions: DRUG: baricitinib treatment|DRUG: adalimumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Mediterranean-style Breakfast and Postprandial Lipid Disorders in Obese Pre-adolescents and Adults
Status: COMPLETED
Conditions: Obesity
Interventions: DIETARY_SUPPLEMENT: Mediterranean-style breakfast|DIETARY_SUPPLEMENT: Western-style breakfast
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Motor Imagery for Reach-to-grasp Rehabilitation After Tetraplegia
Status: COMPLETED
Conditions: Tetraplegia C5-C6|Tetraplegia C6-C7
Interventions: PROCEDURE: motor imagery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Postoperative Ibuprofen and the Risk of Bleeding After Tonsillectomy With or Without Adenoidectomy
Status: COMPLETED
Conditions: Tonsillectomy|Adenoidectomy
Interventions: DRUG: Ibuprofen|DRUG: Acetaminophen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Utility of Restrata With Split-thickness Skin Graft to Reconstruct the Forearm Donor Site
Status: TERMINATED
Conditions: Head and Neck Cancer
Interventions: DEVICE: Restrata Graft|PROCEDURE: Standard of Care Skin Graft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating Remote Ischemic Conditioning (RIC) and Standard of Care vs. Sham Therapy and Standard Care
Status: WITHDRAWN
Conditions: Diabetic Foot Ulcer
Interventions: DEVICE: Remote Ischemic Conditioning (RIC) Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Study of Pembrolizumab, DPX-Survivac Vaccine and Cyclophosphamide in Advanced Ovarian, Primary Peritoneal or Fallopian Tube Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Cancer|Ovarian Cancer|Primary Peritoneal Carcinoma|Fallopian Tube Cancer
Interventions: DRUG: Pembrolizumab|BIOLOGICAL: DPX-Survivac|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Romiplostim (AMG 531) to Treat ITP in Pediatric Subjects
Status: COMPLETED
Conditions: Idiopathic Thrombocytopenic Purpura|Thrombocytopenia in Pediatric Subjects With Immune (Idiopathic) Thrombocytopenic Purpura (ITP)|Thrombocytopenia in Subjects With Immune (Idiopathic) Thrombocytopenic Purpura (ITP)
Interventions: DRUG: Placebo|DRUG: AMG 531
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CBT-I Augmentation of Medication for Drinking in AUD
Status: ACTIVE_NOT_RECRUITING
Conditions: Alcohol Use Disorder With Insomnia
Interventions: BEHAVIORAL: Cognitive Behavioral Therapy for Insomnia|BEHAVIORAL: Sleep Hygiene Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Novel Fiber on Glucose Metabolism and Insulin Sensitivity
Status: COMPLETED
Conditions: Insulin Resistance
Interventions: DIETARY_SUPPLEMENT: Novel dietary fiber|DIETARY_SUPPLEMENT: Novel dietary fiber|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety and Efficacy of Treatment With Azzalure, Restylane/Emervel Filler and Restylane Skinbooster
Status: COMPLETED
Conditions: Facial Aesthetic Treatment
Interventions: DRUG: Azzalure|DEVICE: Restylane/Emervel filler|DEVICE: Restylane Skinbooster
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of Cabergoline Compared With Placebo for the Treatment of RLS
Status: COMPLETED
Conditions: Restless Legs Syndrome
Interventions: DRUG: Cabergoline|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Single Agent Decitabine in TP53 Mutated Relapsed/Refractory Acute Myeloid Leukemia
Status: TERMINATED
Conditions: Acute Myeloid Leukemia|Acute Myeloid Leukemia, Relapsed, Adult
Interventions: DRUG: Decitabine|PROCEDURE: Bone marrow biopsy/aspirate|PROCEDURE: Peripheral blood draw|PROCEDURE: Skin biopsy|PROCEDURE: Buccal swab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antibiotic Treatment and Long-term Outcomes of Patients With Pseudomyxoma Peritonei of Appendiceal Origin
Status: ACTIVE_NOT_RECRUITING
Conditions: Pseudomyxoma Peritonei|Appendiceal Neoplasms
Interventions: DRUG: PrevPac (Prevacid, Amoxicillin, Clarithromycin)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Use of Platelet-rich Plasma in the Treatment of Chronic Anal Fissure
Status: COMPLETED
Conditions: Fissure in Ano
Interventions: PROCEDURE: Platelet rich plasma injection|DRUG: Nitroglycerin ointment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Differentiation of Bone Sarcomas and Osteomyelitis With Ferumoxytol-Enhanced MRI
Status: COMPLETED
Conditions: Bone Cancer|Chondrosarcoma|Ewing's Sarcoma|Osteosarcoma|Rhabdomyosarcoma|Bone Necrosis|Bone Sarcoma|Osteomyelitis
Interventions: DRUG: Feraheme|PROCEDURE: Magnetic Resonance Imaging (MRI) scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: P3 Study Brodalumab in Treatment of Moderate to Severe Plaque Psoriasis
Status: TERMINATED
Conditions: Moderate to Severe Plaque Psoriasis
Interventions: DRUG: 210 mg brodalumab|DRUG: 140 mg brodalumab|DRUG: ustekinumab|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Epetraborole in Patients With Treatment-refractory MAC Lung Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: MAC Lung Disease|Treatment Refractory MAC Lung Disease
Interventions: DRUG: Epetraborole|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of EMG-Biofeedback Balance Training on Hoffman's Reflex
Status: NOT_YET_RECRUITING
Conditions: Spinal Reflex Excitability|Balance
Interventions: OTHER: Balance Training|OTHER: EMG-Biofeedback Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparative Evaluation of Vitamin C and Injectable-platelet Rich Fibrin in the Management of Thin Gingival Phenotype
Status: NOT_YET_RECRUITING
Conditions: Thin Gingival Biotype
Interventions: DRUG: Vit C|OTHER: injectable PRF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Individually Adapted Therapy Duration for the Treatment of Chronic Hepatitis C Genotype 1 Infection
Status: COMPLETED
Conditions: Hepatitis C, Chronic
Interventions: DRUG: Ribavirin|DRUG: Peginterferon alfa 2b
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of PeriZone PerioPatch in Subjects With Chronic Periodontitis
Status: UNKNOWN
Conditions: Chronic Periodontitis
Interventions: DEVICE: PeriZone PerioPatch|PROCEDURE: Scaling and root planing alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Compare Gabapentin to Tramadol in Children With Chronic Neuropathic or Mixed Pain
Status: TERMINATED
Conditions: Chronic Pain
Interventions: DRUG: gabapentin|DRUG: tramadol|OTHER: placebo tramadol|OTHER: placebo gabapentin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study Investigating the Efficacy and Safety of the Addition of Oral-azacitidine to Salvage Treatment by Gilteritinib in Subjects ≥18 Years of Age With Relapsed/Refractory FLT3-mutated Acute Myeloid Leukemia
Status: RECRUITING
Conditions: AML, Adult|Refractory AML|Relapsed Adult AML|FLT3-TKD Mutation|FLT3-ITD
Interventions: DRUG: AzaCITIDine Oral Tablet|DRUG: Xospata
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pharmacokinetic and Pharmacodynamic Study of Once-Daily and Twice-Daily Dosing With Canagliflozin in Healthy Adult Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Canagliflozin 300 mg once daily and 150 mg twice daily|DRUG: Canagliflozin 100 mg once daily and 50 mg twice daily
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Combination Therapy of Rt-PA and Eptifibatide to Treat Acute Ischemic Stroke
Status: COMPLETED
Conditions: Ischemic Stroke|Stroke|Brain Infarction
Interventions: DRUG: Eptifibatide|DRUG: rt-PA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Predicting Postoperative Chemotherapy Efficacy in Patients With Esophageal Squamous Cell Carcinoma
Status: RECRUITING
Conditions: Esophageal Squamous Cell Carcinoma|Chemotherapy Effect|DNA Methylation
Interventions: DRUG: Fluoro Uracil
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: MD1003-AMN MD1003 in Adrenomyeloneuropathy
Status: COMPLETED
Conditions: Adrenomyeloneuropathy|Adrenoleukodystrophy|AMN
Interventions: DRUG: MD1003 100 mg capsule|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Making Pregnant Women With Preterm Birth Threat Watch Nature Images With Virtual Reality Goggles on the Levels of Stress, Anxiety, Attachment, and Care Satisfaction
Status: COMPLETED
Conditions: Psychological Stress|Anxiety|Prenatal Attachment|Pleasure|Virtual Reality|Preterm Birth
Interventions: DEVICE: Watching videos with nature images accompanied by nature sounds with virtual reality glasses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Stereotactic Radiotherapy and Anti-PD1 Antibody (Pembrolizumab) for Oligometastatic Renal Tumours
Status: COMPLETED
Conditions: Renal Cell Carcinoma
Interventions: RADIATION: Stereotactic Ablative Body Radiosurgery (SABR)|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: This is a Multi-center, Single Arm, Open Label Study Intended to Provide Expanded Access to Plerixafor for Patients With Non-Hodgkin's Lymphoma (NHL), Hodgkin's Disease (HD) or Multiple Myeloma (MM) Who Are to Receive Treatment With an Autologous Peripheral Stem Cell Transplant.
Status: NO_LONGER_AVAILABLE
Conditions: Non-Hodgkin's Lymphoma|Hodgkin's Disease|Multiple Myeloma
Interventions: DRUG: Plerixafor
Study Type: EXPANDED_ACCESS
Clinical trial: Habitual and Neurocognitive Processes in Adolescent Obesity Prevention
Status: COMPLETED
Conditions: Obesity|Behavioral Intervention|Obesity Prevention|Diet|Adolescents
Interventions: BEHAVIORAL: Cue and Implementation Intention-Based Intervention|BEHAVIORAL: Control arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Randomized Clinical Trial of Non-Surgical Reperfusion of the Coronary Arteries
Status: COMPLETED
Conditions: Cardiovascular Diseases|Coronary Disease|Heart Diseases|Myocardial Infarction|Myocardial Ischemia
Interventions: DRUG: nitroglycerin|DRUG: streptokinase|PROCEDURE: heart catheterization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety of TETRAXIM™ Given as a Booster Dose at 4 to 6 Years of Age
Status: COMPLETED
Conditions: Diphtheria|Tetanus|Pertussis|Poliomyelitis
Interventions: BIOLOGICAL: DTacP-IPV combined vaccine (TETRAXIM™)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: IS-002 in Prostate Cancer
Status: RECRUITING
Conditions: Prostate Cancer
Interventions: DRUG: Administration of IS-002|DEVICE: Firefly fluorescent imaging|PROCEDURE: robotic-assisted laparoscopic prostatectomy with pelvic lymph node dissection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Dexamethasone, Ofatumumab and Bendamustine (DOT) First-line in Mantle-cell Lymphoma(MCL)
Status: UNKNOWN
Conditions: Lymphoma, Mantle-Cell
Interventions: DRUG: Combination of dexamethasone, ofatumumab and bendamustine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: COMmunity of Practice And Safety Support for Navigating Pain (COMPASS-NP)
Status: RECRUITING
Conditions: Pain Management|Ergonomics|Wounds and Injuries
Interventions: BEHAVIORAL: COMmunity of Practice And Safety Support for Navigating Pain (COMPASS-NP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Randomised Controlled Trial Comparing the Impact of Virtual Reality, Paper and Pencil and Conventional Methods on Stroke Rehabilitation
Status: COMPLETED
Conditions: Stroke
Interventions: PROCEDURE: Virtual Reality|PROCEDURE: Paper and Pencil|PROCEDURE: Conventional Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mindfulness With Biofeedback
Status: COMPLETED
Conditions: Mindfulness Training
Interventions: DEVICE: HeartMath EmWAVE Pro|OTHER: Questionnaires|OTHER: Blood Pressure and Heart Rate|OTHER: Sick Days|OTHER: Patient Satisfaction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy of Arterial Delivery of Autologous Bone Marrow Cells in the Treatment of Insulin-Dependent Diabetes
Status: WITHDRAWN
Conditions: Type 1 Diabetes Mellitus
Interventions: PROCEDURE: autologous bone marrow implantation|OTHER: Saline injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lybridos in Pre-and Postmenopausal Women With Hypoactive Sexual Desire Disorder
Status: COMPLETED
Conditions: Hypoactive Sexual Desire Disorder
Interventions: DRUG: Placebo|DRUG: 0.5 mgTestosterone + 10 mg Buspirone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Zoledronic Acid-loaded Bone Cement as a Local Adjuvant Therapy for Giant Cell Bone Tumor After Intralesional Curettage
Status: RECRUITING
Conditions: Giant Cell Tumor of Bone
Interventions: PROCEDURE: 4mg ZOL loaded gentamicin PMMA|PROCEDURE: gentamicin PMMA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Changes in Incretines, Gut Hormones and Bile Acids After Roux-en-Y Gastric Bypass
Status: COMPLETED
Conditions: Morbid Obesity
Interventions: OTHER: Standardized meal test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Inhaler Trainer Efficacy Study
Status: NOT_YET_RECRUITING
Conditions: Asthma|Copd|Acute Exacerbation of COPD
Interventions: DEVICE: Inhaler Trainer System|OTHER: Initial Inhaler Use Assessment|OTHER: Inhaler Use Instruction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Cardiac Safety Study in Patients With HER2 + Breast Cancer
Status: COMPLETED
Conditions: HER2 Positive Breast Cancer|Left Ventricular Function Systolic Dysfunction
Interventions: DRUG: Trastuzumab|DRUG: Pertuzumab|DRUG: Ado Trastuzumab Emtansine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chiropractic Prone Distraction for Lower Back Pain
Status: TERMINATED
Conditions: Herniated Disc|Lower Back Pain|Sciatica
Interventions: PROCEDURE: Prone Distraction|PROCEDURE: Side-Posture Manipulation|PROCEDURE: Side-Posture Manipulation & Prone Distraction|PROCEDURE: Usual Care (Control Group)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: ABLATE WEIGHT (Ablation Plus ESG for Weight Loss)
Status: ACTIVE_NOT_RECRUITING
Conditions: Obesity
Interventions: PROCEDURE: Fundic Ablation Sequentially in Combination with Endoscopic Sleeve Gastroplasty|DEVICE: Fundic Mucosal Ablation with ERBE HybridAPC|DEVICE: Apollo ESG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Cannabidiol in Knee Osteoarthritis
Status: COMPLETED
Conditions: Osteo Arthritis Knee|Pain, Joint
Interventions: DRUG: Cannabidiol Oral Product|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective Study on the Efficacy and Safety of Bronchoalveolar Lavage Combined With Pathogen Metagenomic Sequencing Technology in the Diagnosis of Immune Checkpoint Inhibitor Associated Pneumonia
Status: RECRUITING
Conditions: Immune Checkpoint Inhibitor Associated Pneumonia
Interventions: DIAGNOSTIC_TEST: Bronchoalveolar lavage and pathogen metagenomic sequencing
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Should Palatine Tonsils be Included in the Oropharyngeal Swab for SARS-CoV-2 Molecular Testing?
Status: RECRUITING
Conditions: SARS-CoV Infection|Coronavirus|Corona Virus Infection
Interventions: PROCEDURE: An Oropharyngeal swab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: EuroPainClinicsStudy XI (Cryo vs RF MB Z Joints)
Status: UNKNOWN
Conditions: Back Pain
Interventions: PROCEDURE: Lumbar medial branch radiofrequency ablation neurotomy|PROCEDURE: Lumbar medial branch cryo ablation neurotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Estradiol Supplementation and Rotator Cuff Repair
Status: NOT_YET_RECRUITING
Conditions: Rotator Cuff Tears|Rotator Cuff Injuries|Rotator Cuff Syndrome|Menopause Related Conditions|Menopause
Interventions: DRUG: Transdermal estrogen|PROCEDURE: Rotator Cuff Repair Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Long-Term Extension of Previous rAvPAL-PEG Protocols in Subjects With PKU (PAL-003)
Status: COMPLETED
Conditions: Phenylketonuria
Interventions: DRUG: rAvPAL-PEG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study on the Safety and Pharmacokinetics of LM001 and Gonal-F® in Healthy Women
Status: UNKNOWN
Conditions: Infertility, Female
Interventions: DRUG: Gonal-F®|DRUG: LM001
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE