pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: New Technologies to Determine Carotid Plaque Vulnerability in Patients With Significant Carotid Plaques
Status: COMPLETED
Conditions: Carotid Artery Plaque
Interventions: COMBINATION_PRODUCT: Contrast-enhanced ultrasound|DEVICE: Shear Wave Elastography|DEVICE: Ultrasound Examination
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: SHR-8068 Combined With Adbelizumab and BP102 in the Treatment of Advanced Colorectal Cancer
Status: NOT_YET_RECRUITING
Conditions: Colorectal Cancer
Interventions: DRUG: SHR-8068|DRUG: Adebrelimab|DRUG: BP102
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 3 Study of DW-330SR2 and Pelubiprofen in Chronic Back Pain Patients
Status: COMPLETED
Conditions: Chronic Back Pain
Interventions: DRUG: DW-330SR2|DRUG: Pelubiprofen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparative Study of Pravastatin vs Placebo as Primary Prevention of Severe Subcutaneous Breast Fibrosis in Hyper-radiosensitive Identified Patients With Breast Cancer
Status: TERMINATED
Conditions: Breast Cancer
Interventions: DRUG: EXPERIMENTAL ARM|OTHER: CONTROL GROUP|RADIATION: Standard adjuvant whole breast radiotherapy (50Gy/ 25 fractions to whole breast) followed or not by a boost to tumor bed (16Gy/ 8 fractions)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Absolute Bioavailability of Oral PCI-32765 and the Effect of Grapefruit Juice on the Bioavailability of PCI-32765 in Healthy Participants
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: PCI-32765 (Treatment A)|DRUG: PCI-32765 (Treatment B)|DRUG: PCI-32765 (Treatment C)|DRUG: 13C6 PCI-32765 (reference)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Different Amounts of Moxibustion in the Treatment of DPN: A Clinical RCT Study
Status: NOT_YET_RECRUITING
Conditions: Diabetic Peripheral Neuropathy|Pain|Moxibustion|Randomized Controlled Trial
Interventions: OTHER: Moxibustion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tramadol Versus Dexamethasone as Adjuvant to Levobupivacaine Supraclavicular Block
Status: UNKNOWN
Conditions: Regional Anesthesia
Interventions: DRUG: Levobupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Regorafenib in Good Performance Status Patients With Newly Diagnosed Metastatic Colorectal Adenocarcinoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Colorectal Adenocarcinoma
Interventions: DRUG: Regorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Minocycline and N-acetylcysteine for the Treatment of Fibromyalgia
Status: COMPLETED
Conditions: Fibromyalgia
Interventions: DRUG: minocycline (200 mg daily) and NAC (1200 mg daily) followed by placebo|DRUG: Placebo followed by minocycline (200 mg daily) and NAC (1200 mg daily)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ezetimibe as a Safe and Efficacious Treatment for Chronic Hepatitis C
Status: TERMINATED
Conditions: Chronic Hepatitis C
Interventions: DRUG: 20mg ezetimibe|DRUG: Placebo|DRUG: 40mg ezetimibe
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Postpartum Family Planning
Status: TERMINATED
Conditions: Delay in Time to Lactogenesis Stage II
Interventions: DRUG: Depo-Provera Injectable Product|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SOLID-Effect of Risedronate Sodium at Distal Radius in Colle's Fracture.
Status: COMPLETED
Conditions: Colles' Fracture
Interventions: DRUG: Risedronate sodium|DRUG: Calcium & Vitamine D3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multi-layer Data to Improve Diagnosis, Predict Therapy Resistance and Suggest Targeted Therapies in HGSOC
Status: RECRUITING
Conditions: High Grade Ovarian Serous Adenocarcinoma|High Grade Serous Carcinoma
Interventions: GENETIC: WGS and RNA sequencing|GENETIC: circulating tumor DNA (ctDNA)|DIAGNOSTIC_TEST: FDG PET/CT imaging
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: PROlonGed ExpoSure Sertraline
Status: COMPLETED
Conditions: Posttraumatic Stress Disorder
Interventions: DRUG: Sertraline|BEHAVIORAL: Prolonged Exposure Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phacoemulsification Versus Phacoemulsification With Micro-bypass Stent
Status: COMPLETED
Conditions: Primary Angle-Closure Glaucoma|Primary Angle Closure Without Glaucoma Damage
Interventions: DEVICE: iStent implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Travoprost New Formulations in Patients With Open-Angle Glaucoma or Ocular Hypertension
Status: COMPLETED
Conditions: Ocular Hypertension|Open-angle Glaucoma
Interventions: DRUG: Travoprost ophthalmic solution (new formulation)|DRUG: Travoprost ophthalmic solution, 0.004%|DRUG: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: CD19 CART Cells for Patients With Relapse and Refractory CD19+ B-cell Lymphoma.
Status: UNKNOWN
Conditions: B Cell Lymphoma
Interventions: DRUG: Fludarabine|DRUG: Cyclophosphamide|BIOLOGICAL: CD19 CART
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study on the Safety, Tolerability and Immune Response of SARS-CoV-2 Sclamp (COVID-19) Vaccine in Healthy Adults
Status: COMPLETED
Conditions: SARS-CoV2|Covid19
Interventions: BIOLOGICAL: MF59 adjuvanted SARS-CoV-2 Sclamp vaccine 5mcg|BIOLOGICAL: MF59 adjuvanted SARS-CoV-2 Sclamp vaccine 15mcg|BIOLOGICAL: MF59 adjuvanted SARS-CoV-2 Sclamp vaccine 45mcg|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Right Colon Polyp Miss Rates of Water Exchange and Carbon Dioxide Insufflation Colonoscopy
Status: COMPLETED
Conditions: Right Colon Adenoma Miss Rate|Right Colon Hyperplastic Polyp Miss Rate
Interventions: PROCEDURE: Colon polypectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety & Efficacy Study High Dose Evomela Injection for MA Conditioning in MM Patients With Autologous Transplantation
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: High-Dose Melphalan HCL for Injection (Propylene Glycol-Free)|OTHER: Autologous Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Determine the Effect of Food on the Blood Levels of AZD9291 Following Oral Dosing of a Tablet Formulation in Patients With Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Advanced Non Small Cell Lung Cancer|Advanced (Inoperable) Non Small Cell Lung Cancer
Interventions: DRUG: AZD9291 tablets|PROCEDURE: Pharmacokinetic sampling - AZD9291|OTHER: Dietary Fasted|OTHER: Dietary High Fat|PROCEDURE: Pharmacokinetic sampling - AZ5140 and AZ7550
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: OTHER
Clinical trial: Bihemispheric Transcranial Direct Current Stimulation* on Speech Fluency
Status: RECRUITING
Conditions: Stuttering, Adult
Interventions: DEVICE: Transcranial direct current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Cannabis Abstinence on Symptoms and Cognition in Depression
Status: COMPLETED
Conditions: Cannabis Use Disorder|Major Depressive Disorder|Cognition
Interventions: BEHAVIORAL: Weekly Behavioral Coaching Session|BEHAVIORAL: Contingency Management
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Air Versus Saline Solution for the Localization of the Epidural Space in Labour Analgesia
Status: COMPLETED
Conditions: Effects of Anesthesia Spinal and Epidural in Pregnancy
Interventions: PROCEDURE: air in epidural space|PROCEDURE: saline in epidural space
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Agatolimod and Trastuzumab in Treating Patients With Locally Advanced or Metastatic Breast Cancer
Status: TERMINATED
Conditions: Breast Cancer
Interventions: DRUG: Trastuzumab|DRUG: PF03512676|OTHER: Correlative Studies
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Continuous Erector Spinea Block Versus Intravenous Analgesia in Coronary Bypass Surgery
Status: COMPLETED
Conditions: Erector Spinea Block in Open Heart Surgery
Interventions: OTHER: continous erector spinea block|DRUG: intravenous narcotics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Angel Sounds and Guided Imagery Technique Played to Expectant Couples
Status: COMPLETED
Conditions: Listen to Fetal Heartbeat
Interventions: OTHER: Group-FHB|OTHER: Group-GIT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study of the Effects of Itraconazole or Carbamazepine on LY3537982 in Healthy Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: LY3537982|DRUG: Itraconazole|DRUG: Carbamazepine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Primary Tumor Radiotherapy Omitting CTV for Patients With Advanced NSCLC Responded to Immunotherapy and Chemotherapy
Status: RECRUITING
Conditions: Advanced Non-Small Cell Squamous Lung Cancer|Radiotherapy|Immunotherapy
Interventions: RADIATION: CTV omitted or delineated
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Phase 4 Study Investigating the Efficacy of Retaine™ in Managing Signs and Symptoms Associated With Dry Eye Syndrome
Status: COMPLETED
Conditions: Keratoconjunctivitis Sicca
Interventions: DRUG: Retaine™
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Ultrasound Imaging Technique to Measure Tumors in People With Pancreatic Ductal Adenocarcinoma (PDAC) or Gastrointestinal (GI) Adenocarcinoma
Status: RECRUITING
Conditions: Pancreas Cancer|Gastrointestinal Adenocarcinoma
Interventions: DIAGNOSTIC_TEST: ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Cord Blood Transplant in Adults With Blood Cancers
Status: RECRUITING
Conditions: Acute Myelogenous Leukemia (AML)|Acute Lymphoblastic Leukemia (ALL)|Chronic Myelogenous Leukemia (CML)|Myelodysplastic Syndromes (MDS)|Myeloproliferative Disorder|Non-Hodgkin's Lymphoma
Interventions: DRUG: Conditioning Chemotherapy|BIOLOGICAL: Cord blood graft
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Longitudinal Study for the Development of Innovative Wearable Tools for Foetal Wellbeing Monitoring
Status: COMPLETED
Conditions: Foetal Wellbeing
Interventions: DEVICE: TMSi Porti|DEVICE: Bloomlife sensor
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Decrease Opioid Consumption With Intra-Venous (IV) Acetaminophen After Colorectal Surgery (DOCIVA)
Status: COMPLETED
Conditions: Pain Control Post Colorectal Surgery
Interventions: DRUG: IV Acetaminophen|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Conversations in Light and Shadow: Assessing Phototherapy's Impact on Breast Cancer Patients
Status: NOT_YET_RECRUITING
Conditions: Breast Cancer|Breast Cancer Female|Randomized Controlled Trial
Interventions: BEHAVIORAL: photography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Utility of 18F-fluorocholine PET/CT in the Imaging of Parathyroid Adenomas
Status: COMPLETED
Conditions: Hyperparathyroidism|Parathyroid Adenoma
Interventions: DIAGNOSTIC_TEST: We assessed sensitivity of 18F-FCH PET/CT in preoperative localisation of hyperfunctioning parathyroid tissue in patients with primary hyperparathyroidism
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparing the Effects of Manual Hyperinflation and Diaphragmatic Proprioceptive Neuromuscular Facilitation on Pulmonary Functions in Patients on Mechanical Ventilation
Status: RECRUITING
Conditions: COPD Exacerbation Acute
Interventions: DEVICE: manual hyperinflation|OTHER: Diaphragmatic proprioceptive neuromuscular facilitation technique|OTHER: traditional physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study of CD19 CAR NK Cells for the Treatment of Relapsed/Refractory B-cell Related Autoimmune Diseases
Status: RECRUITING
Conditions: Autoimmune Diseases
Interventions: DRUG: anti-CD19 CAR NK cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial of Centanafadine Efficacy and Safety in Children With Attention-deficit/ Hyperactivity Disorder (ADHD)
Status: RECRUITING
Conditions: Attention Deficit/Hyperactivity Disorder
Interventions: DRUG: centanafadine capsule|OTHER: placebo capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Role of Adrenaline in in the Inflammatory Response in Diabetes
Status: NOT_YET_RECRUITING
Conditions: Inflammatory Response|Diabetes type1|Hypoglycemia
Interventions: DRUG: Adrenaline
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: SENS-401 to Prevent the Ototoxicity Induced by Cisplatin in Adult Subjects With a Neoplastic Disease
Status: RECRUITING
Conditions: Hearing Loss Ototoxic
Interventions: DRUG: SENS-401 (R-Azasetron Besylate)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Analysis of the Effects of LED Phototherapy and Electrical Stimulation in the Healing of Diabetic Ulcers
Status: UNKNOWN
Conditions: Ulcer|Diabetes Mellitus
Interventions: DEVICE: Light emitting diodes (LED)|DEVICE: Fixed diphasic current
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Probiotics Reduce Incidence of Necrotizing Enterocolitis for Very Low Birth Weight Infants
Status: TERMINATED
Conditions: Enterocolitis, Necrotizing
Interventions: DIETARY_SUPPLEMENT: infloran|DIETARY_SUPPLEMENT: infloran
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Utility of Food-Specific IgE Measured With the IMMULITE 2000 Assay to Predict Symptomatic Food Allergy
Status: COMPLETED
Conditions: Peanut Allergy|Milk Allergy|Egg Allergy
Interventions: PROCEDURE: Oral food challenge
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Multicentre, Open Label, Randomized, Two-arm, Parallel-group Study to Assess Efficacy and Safety of ENVARSUS® Compared With Tacrolimus Used as Per Current Clinical Practice in the Initial Maintenance Setting in de Novo Kidney Transplant Patients
Status: COMPLETED
Conditions: End Stage Renal Disease
Interventions: DRUG: ENVARSUS®|DRUG: PROGRAF®|DRUG: ADVAGRAF®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Busulfan, Melphalan, and Thiotepa in Treating Patients Who Are Undergoing an Autologous Stem Cell Transplant for Hodgkin's or Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: BIOLOGICAL: filgrastim|DRUG: busulfan|DRUG: melphalan|DRUG: thiotepa|PROCEDURE: bone marrow ablation with stem cell support|PROCEDURE: peripheral blood stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Different Stapler Cartridge For Pancreatic Stump Texture To Prevent Pancreatic Fistula
Status: COMPLETED
Conditions: Pancreatic Neoplasms|Pancreatic Fistula
Interventions: PROCEDURE: traditional reloads|PROCEDURE: Tri-Staple reloads
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Effects of Home Therapeutic Exercises Oriented for Patients With Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: BEHAVIORAL: Exercises oriented, manual and monitoring by phone|BEHAVIORAL: Exercises oriented, manual and without monitoring by phone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Development of Knee Osteoarthritis After Arthroscopic Partial Resection of Degenerative Meniscus Tear
Status: UNKNOWN
Conditions: Osteoarthritis of the Knee|Arthroscopy|Meniscal Tear
Interventions: PROCEDURE: Arthroscopic partial meniscectomy|PROCEDURE: Arthroscopy (diagnostic)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of SP2086 as Monotherapy in Patients With Type 2 Diabetes
Status: UNKNOWN
Conditions: Type 2 Diabetes
Interventions: DRUG: Placebo|DRUG: SP2086 50 mg b.i.d.|DRUG: SP2086 100 mg q.d.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Urinary Activin A as Apredictive Marker for Assessement of Acute Kidney Injury Severity in Patient Admitted at Assuit University Hospital
Status: NOT_YET_RECRUITING
Conditions: Urinary Activin A in AKI
Interventions: OTHER: Urinary activin A in AKI
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Intelligent Control Approach to Anemia Management
Status: COMPLETED
Conditions: End-Stage Renal Disease
Interventions: OTHER: ESA Dose Adjustment per standard Anemia Management Protocol|OTHER: ESA Dose Adjustment per "Smart Anemia Manager" Algorithm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: OTHER
Clinical trial: Nebulised Rt-PA for ARDS Due to COVID-19
Status: UNKNOWN
Conditions: COVID
Interventions: DRUG: nebulised recombinant tissue-Plasminogen Activator (rt-PA) - Cohort 1|DRUG: nebulised recombinant tissue-Plasminogen Activator (rt-PA) - Cohort 2 IMV|DRUG: nebulised recombinant tissue-Plasminogen Activator (rt-PA) - Cohort 2 NIV
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing the Bioequivalence of Triamcinolone Acetonide Aqueous Nasal Spray (Apotex, Inc.) to That of Nasacort® AQ Nasal Spray (Sanofi-Aventis Pharmaceutical Products, Inc.) In the Treatment of Seasonal Allergic Rhinitis
Status: COMPLETED
Conditions: Seasonal Allergic Rhinitis
Interventions: DRUG: triamcinolone acetonide aqueous nasal spray (Apotex Inc.)|DRUG: triamcinolone acetonide aqueous nasal spray (Nasacort® AQ)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Chronic Itch in Atopic Dermatitis With Topical Naltrexone
Status: WITHDRAWN
Conditions: Atopic Dermatitis|Pruritus|Dermatitis
Interventions: DRUG: Naltrexone|OTHER: Placebo Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Behavioral Pharmacology of THC and Alpha-pinene
Status: COMPLETED
Conditions: THC|Alpha-pinene
Interventions: DRUG: Placebo|DRUG: THC|DRUG: Alpha-Pinene
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Phase II Trial of Ofatumumab in Subjects With Waldenstrom's Macroglobulinemia
Status: COMPLETED
Conditions: Waldenstrom Macroglobulinaemia
Interventions: BIOLOGICAL: Ofatumumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasound Versus Kinesiotaping in Shoulder Impingement Syndrome
Status: ENROLLING_BY_INVITATION
Conditions: Shoulder Impingement Syndrome
Interventions: BEHAVIORAL: scapular stabilization exercises|DEVICE: ultrasound|OTHER: Kinesio Tape
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Imaging of Neuroendocrine Tumors With PET and Fluoro-18-DOPA (F-DOPA)
Status: COMPLETED
Conditions: Neuroendocrine Tumors
Interventions: PROCEDURE: F-18-F-DOPA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Randomized Controlled Study of Medical-education-community Collaborated Intervention in Children With ADHD
Status: WITHDRAWN
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: BEHAVIORAL: Medical-education-community Collaborated Intervention|BEHAVIORAL: routine clinical care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of GSK3359609 With Pembrolizumab and 5-fluorouracil (5-FU)-Platinum Chemotherapy in Participants With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma
Status: TERMINATED
Conditions: Neoplasms, Head and Neck
Interventions: DRUG: Feladilimab|DRUG: Pembrolizumab|DRUG: Placebo|DRUG: Platinum based chemotherapy|DRUG: Fluorouracil (5FU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of BCX7353 as a Treatment for Attacks of Hereditary Angioedema
Status: COMPLETED
Conditions: Hereditary Angioedema (HAE)
Interventions: DRUG: BCX7353|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Valsartan With Amlodipine in Hypertensive Patients With Glucose Intolerance
Status: COMPLETED
Conditions: Hypertension|Type 2 Diabetes Mellitus
Interventions: DRUG: Valsartan|DRUG: Amlodipine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: 4-weekly Versus 12-weekly Administration of Bone-targeted Agents in Patients With Bone Metastases
Status: COMPLETED
Conditions: Breast Cancer|Prostate Cancer|Metastasis
Interventions: DRUG: Pamidronate|DRUG: Denosumab|DRUG: Zoledronate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Single and Multiple Doses of PRS-220 Administered by Oral Inhalation in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Placebo|DRUG: PRS-220
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Mesenchymal Stromal Cells for Traumatic Brain Injury
Status: RECRUITING
Conditions: Traumatic Brain Injury With Loss of Consciousness
Interventions: DRUG: Mesenchymal stromal cell low dosage-80*10^6 cells|DRUG: Mesenchymal stromal cell low dosage-160*10^6 cells|OTHER: Placebo-storage solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety of Laparoscopic Resection for Gastrointestinal Stromal Tumor on Unfavorable Anatomic Site of Stomach
Status: RECRUITING
Conditions: Gastrointestinal Stromal Tumors
Interventions: PROCEDURE: Laparoscopic resection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ethosuximide and Pentoxifylline in the Treatment of Abdominal Pain Related to Irritable Bowel Syndrome
Status: RECRUITING
Conditions: IBS - Irritable Bowel Syndrome
Interventions: DRUG: pentoxyifylline|DRUG: Mebeverine|DRUG: ethosuximide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Nitrate Supplementation; Source
Status: COMPLETED
Conditions: Blood Pressure|Nutritional Physiological Phenomena
Interventions: DIETARY_SUPPLEMENT: Sodium nitrate|DIETARY_SUPPLEMENT: Beetroot juice|DIETARY_SUPPLEMENT: Spinach|DIETARY_SUPPLEMENT: Rocket salad
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Dietary Intervention With Probiotic Pasta and Evaluation of the Effects on Metabolic and Inflammatory Status
Status: COMPLETED
Conditions: Overweight and Obesity
Interventions: OTHER: Probiotic Pasta|OTHER: Control Pasta
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Esophageal Stent Migration With Endoscopic Suture Fixation Compared to Standard Deployment
Status: WITHDRAWN
Conditions: Esophageal Strictures|Esophageal Leak|Esophageal Perforation|Esophageal Fistula|Endostitch|Esophageal Stent
Interventions: PROCEDURE: FCSEMS with Endostitch (ES)|PROCEDURE: FCSEMS with No Suturing (NS)|DEVICE: Fully Covered Self-Expanding Metal Stents (FCSEMS)|DEVICE: EndoStitch (ES) with the OverStitchTM system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Dolutegravir Study in HIV-1 Participants Completing IMPAACT Studies P1093 and P2019
Status: ACTIVE_NOT_RECRUITING
Conditions: HIV Infections
Interventions: DRUG: Dolutegravir film-coated tablets|DRUG: Dolutegravir film-coated dispersible tablets|DRUG: ABC/DTG/3TC immediate release tablets|DRUG: ABC/DTG/3TC film-coated dispersible tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Outcomes of Subthreshold Laser Versus Intravitreal Injection of Ranibizumab in Diabetic Macular Edema
Status: COMPLETED
Conditions: Diabetic Macular Edema
Interventions: PROCEDURE: laser interference,INTRAVITREAL INJECTION
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Is High Sensibility Troponins a Dialysable Marker in Hemodialysis Patients and Does it Have Prognostic Value?
Status: COMPLETED
Conditions: Renal Failure
Interventions: OTHER: Hs-TNT dosage
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Extending the Time Window for Tenecteplase by Recanalization of Basilar Artery Occlusion in Posterior Circulation Stroke
Status: RECRUITING
Conditions: Basilar Artery Occlusion
Interventions: DRUG: Tenecteplase|DRUG: Standard Care (which may include intravenous Alteplase)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Linezolid in the Treatment of Hemodialysis Patients With Catheter-Related Gram-Positive Bloodstream Infections
Status: TERMINATED
Conditions: Bacteremia|Gram-Positive Bacterial Infections
Interventions: DRUG: Cefazolin IV|DRUG: Linezolid IV|DRUG: Vancomycin (IV)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Nebivolol Versus Carvedilol on Cardiopulmonary Function at High Altitude in Healthy Subjects.
Status: COMPLETED
Conditions: Hypoxia|Altitude|Heart Failure
Interventions: DRUG: placebo|DRUG: Carvedilol|DRUG: Nebivolol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Generic and Original Formulation of Clopidogrel
Status: COMPLETED
Conditions: Coronary Heart Disease|Percutaneous Coronary Intervention
Interventions: DRUG: Plavix|DRUG: Kardogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation of a Transcranial Stimulation With Direct Current on Language Disorders in Semantic Dementia
Status: RECRUITING
Conditions: Semantic Dementia
Interventions: DEVICE: Transcranial stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Acupressure After Angiography on Pain Level and Hemodynamic Variables
Status: COMPLETED
Conditions: Acupressure|Pain|Hemodynamic Instability|Angiopathy, Peripheral
Interventions: OTHER: Acupressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study to Assess the Bioavailability of Ticagrelor OD Tablet vs. IR Tablet
Status: COMPLETED
Conditions: Bioavailability|Healthy Subjects
Interventions: DRUG: Ticagrelor OD tablet (90 mg single dose) administered with 200 ml of water|DRUG: Ticagrelor OD tablet (90 mg single dose) administered without water|DRUG: Ticagrelor OD tablet (90 mg single dose) suspended in water administered via nasogastric tube|DRUG: Brilique®, Ticagrelor IR tablet (90 mg) administered with 200mL of water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effectiveness of rTMS in Depressed VA Patients
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DEVICE: rTMS|DEVICE: Sham Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lifestyle Online Intervention On EB and BMI On Obese Hypertensive Adults
Status: COMPLETED
Conditions: Hypertension|Obesity
Interventions: BEHAVIORAL: VIVIR MEJOR EXPERIMENTAL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vitamin E for NASH Treatment in HIV Infected Individuals
Status: TERMINATED
Conditions: NAFLD|NASH - Nonalcoholic Steatohepatitis|HIV Infections
Interventions: DRUG: Vitamin E|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Autologous Stem Cell Transplantation for Early Onset Type I Diabetes Mellitus
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus
Interventions: PROCEDURE: Immunosuppression and autologous stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Smartwatches for Detection of Atrial Fibrillation (AFib) in Secondary Prevention of Cryptogenic Stroke
Status: NOT_YET_RECRUITING
Conditions: Ischemic Stroke, Cryptogenic|Transient Ischemic Attack|Atrial Fibrillation
Interventions: DEVICE: Smartwatch
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Nifedipine for Acute Tocolysis of Preterm Labor
Status: COMPLETED
Conditions: Preterm Labor
Interventions: DRUG: Nifedipine|DRUG: Placebo|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Vitamin E Pharmacokinetics and Biomarkers in Normal and Obese Women
Status: COMPLETED
Conditions: Diabetes|Fatty Liver|Obesity|Healthy Volunteers
Interventions: DRUG: Alpha tocopherol|OTHER: Vitamin E|OTHER: Vitamin C
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate Safety, PK, Efficacy of TLC590 for Postsurgical Pain Management Following Bunionectomy
Status: COMPLETED
Conditions: Hallux Valgus
Interventions: DRUG: TLC590|DRUG: Naropin®|DRUG: Normal Saline|DRUG: Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of Immunogenicity, Safety and Antibody Persistence of COVID-19 Booster Vaccine (Produced in Beijing) in Patients With Hypertension and/or Diabetes
Status: UNKNOWN
Conditions: COVID-19 Pneumonia
Interventions: BIOLOGICAL: Covid-19 vaccine (0-1-4 schedule)|BIOLOGICAL: Covid-19 vaccine (0-1-6 schedule)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: RayOne EMV Mini-monovision - Efficiency and Safety of 3 Grades of Mini-monovision
Status: UNKNOWN
Conditions: Cataract Senile|Presbyopia
Interventions: PROCEDURE: intraocular lens - RayOne EMV (Rayner Surgical GmbH,Berlin, Deutschland)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of LEO 43204 in Field Treatment of Actinic Keratosis on Face or Chest Including 12-month Follow-up
Status: COMPLETED
Conditions: Actinic Keratosis
Interventions: DRUG: LEO 43204 gel|DRUG: Vehicle gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Cigarette and E-cigarette Menthol Regulation on Current Smokers of Menthol Cigarettes
Status: RECRUITING
Conditions: Smoking Prevention and Control
Interventions: BEHAVIORAL: Non-Menthol Cigarettes|BEHAVIORAL: Tobacco Flavored E-cigarettes|BEHAVIORAL: Menthol Cigarettes|BEHAVIORAL: Menthol Flavored E-cigarettes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Probiotics in the Reduction of Adverse Effects and Dysbiosis of H. Pylori Eradication
Status: UNKNOWN
Conditions: Helicobacter Pylori Infection
Interventions: DRUG: Vigiis 101-LAB and sequential therapy|DRUG: Placebo and sequential therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Evaluate Efficacy of New Paracetamol Formulation Compared to Ibuprofen in Headache
Status: TERMINATED
Conditions: Pain
Interventions: DRUG: Paracetamol and Caffeine|DRUG: Ibuprofen|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Serratus Anterior Plane Block Versus Pericapsular Nerve Group Block for Shoulder Surgery
Status: COMPLETED
Conditions: Shoulder Surgery
Interventions: PROCEDURE: Serratus anterior plane block|PROCEDURE: PENG block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sensory-specific Peripheral Stimulation for Tremor Management
Status: RECRUITING
Conditions: Parkinson's Disease|Essential Tremor
Interventions: DEVICE: Peripheral electrical stimulation|DEVICE: Single pulse TMS
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Physiological Effects of FGF21 on Alcohol Preference and Glucose Metabolism
Status: ACTIVE_NOT_RECRUITING
Conditions: Fibroblast Growth Factor 21|Tast Perference
Interventions: OTHER: Fibroblast growth factor 21 infusion|OTHER: Placebo infusion (saline)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Efficacy of 7-day Versus 14-day Bismuth Quadruple Therapy for the Eradication of Helicobacter Pylori（SHARE2302)
Status: RECRUITING
Conditions: Helicobacter Pylori Infection
Interventions: PROCEDURE: 7days bismuth quadruple|PROCEDURE: 14 days bismuth quadruple
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TPIV200/huFR-1 (A Multi-Epitope Anti-Folate Receptor Vaccine) Plus Anti-PD-L1 MEDI4736 (Durvalumab) in Patients With Platinum Resistant Ovarian Cancer
Status: COMPLETED
Conditions: Ovarian Cancer
Interventions: BIOLOGICAL: TPIV200|BIOLOGICAL: Durvalumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Use of VAC System in Transplants of Leg Ulcers Versus Usual Dressing Method
Status: TERMINATED
Conditions: Leg Ulcer
Interventions: DEVICE: V.A.C.®|DEVICE: dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Primary Liver Tumors With Electrochemotherapy (ECT)
Status: COMPLETED
Conditions: Liver Cancer
Interventions: PROCEDURE: Electrochemotherapy|DEVICE: Cliniporator Vitae®|DRUG: Bleomycin PHC 15 e. (United States Pharmacopeia - USP)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ezrin Peptide (HEP-1) for Treatment of Coronavirus Disease (COVID-19) Infection
Status: UNKNOWN
Conditions: Covid19|Treatment|Corona Virus Infection
Interventions: DRUG: Human Ezrin Peptide 1 (HEP1)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Peripheral Nerve Blocks on Postoperative Analgesia in Elective Cesarean Section
Status: COMPLETED
Conditions: Anesthesia; Sexual|Analgesia
Interventions: PROCEDURE: Patients undergoing transversalis fascia plane block|PROCEDURE: Patients undergoing transversus abdominis plane block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Tofacitinib in Treating ANCA-associated Vasculitis
Status: COMPLETED
Conditions: ANCA Associated Vasculitis|Drug Use|JAK-STAT Pathway Deregulation
Interventions: DRUG: Tofacitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Short-term Insulin Intensive Therapy Based on the Application of Insulin Pump and Real-time Dynamic Glucose Monitoring Technology on Reversing the Newly Diagnosed Type 2 Diabetes
Status: RECRUITING
Conditions: Insulin Pump，Continuous Glucose Monitoring Technology
Interventions: DRUG: Insulin Glargine|DRUG: Metformin|DRUG: Dapagliflozin|DRUG: Insulin aspart
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety & Efficacy of Ischemic Preconditioning by Embolization of the Inferior Mesenteric Artery in Surgery for Tumors of Lower and Middle Rectum
Status: RECRUITING
Conditions: Cancer, Rectal
Interventions: PROCEDURE: Ischemic preconditioning|PROCEDURE: Arteriogram
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ergot and Oxytocin During Cesarean Delivery Following Failure to Progress in Labour
Status: COMPLETED
Conditions: Blood Loss, Surgical
Interventions: DRUG: Methyl-Ergonovine-Oxytocin|DRUG: Oxytocin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: The Tolerability and Pharmacokinetics Clinical Trial of Metacavir Enteric-coated Capsules in Healthy Adult Volunteers
Status: COMPLETED
Conditions: Chronic Hepatitis B
Interventions: DRUG: PNA|DRUG: PNA placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Drug Interaction Study Between Bosutinib And Dabigatran
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Dabigatran|DRUG: Bosutinib|DRUG: Dabigatran
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety and Tolerability of Acanya Gel in Combination With Atralin Gel for Acne Vulgaris
Status: UNKNOWN
Conditions: Acne Vulgaris
Interventions: DRUG: Benzoyl peroxide 2.5%/clindamycin phosphate 1.2% in the morning with with tretinoin 0.05% gel in the evening
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Efficacy and Safety of ITI-1284 in the Treatment of Psychosis Associated With Alzheimer's Disease
Status: RECRUITING
Conditions: Psychosis Associated With Alzheimer's Disease
Interventions: DRUG: ITI-1284|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MTT for Children With ASD Who Have Gastrointestinal Disorders
Status: ACTIVE_NOT_RECRUITING
Conditions: Autism Spectrum Disorder|Gastro-Intestinal Disorder|Constipation|Diarrhea
Interventions: COMBINATION_PRODUCT: vancomycin, Miralax, intestinal microbiota|COMBINATION_PRODUCT: placebo vancomycin, Miralax, placebo intestinal microbiota
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Power Mobility on Young Children With Severe Motor Impairments
Status: COMPLETED
Conditions: Cerebral Palsy|Arthrogryposis|Spinal Muscular Atrophy|Other Central Nervous System or Musculoskeletal Disorders
Interventions: OTHER: Power mobility
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Platform Study for Prostate Researching Translational Endpoints Correlated to Response to Inform Use of Novel Combinations
Status: COMPLETED
Conditions: Metastatic Castration-resistant Prostate Cancer
Interventions: DRUG: NKTR-214 (Cohort A)|DRUG: Nivolumab (Cohort A, B and C)|RADIATION: Stereotactic body radiation therapy (SBRT) (Cohort B)|DRUG: CDX-301 (Cohort B and C)|DRUG: Poly-ICLC (Cohort B)|DRUG: INO-5151 (Cohort C)|DEVICE: Cellectra 2000
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Promoting Risk Reduction Among Young Adults With Asthma During Wildfire Smoke Events (TRAK)
Status: COMPLETED
Conditions: Asthma
Interventions: BEHAVIORAL: Smoke Sense|BEHAVIORAL: Smoke Sense Plus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Transdiagnostic Sleep and Circadian Treatment to Improve Community SMI Outcomes
Status: COMPLETED
Conditions: Mental Disorders
Interventions: BEHAVIORAL: Transdiagnostic Intervention for Sleep and Circadian Dysfunction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT