pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Motor Imagery in Aphantasia
Status: RECRUITING
Conditions: Aphasia
Interventions: PROCEDURE: High-definition transcranial direct current (HD-tDCS), active condition|PROCEDURE: High-definition transcranial direct current (HD-tDCS), sham condition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Syringe or Continuous Amnioreduction for Symptomatic Polyhydramnios. A Prospective Randomized Study.
Status: COMPLETED
Conditions: Polyhydramnios
Interventions: DEVICE: syringe aspiration|DEVICE: Wall suction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Performance of Two Daily Disposable Silicone Hydrogel Contact Lenses
Status: COMPLETED
Conditions: Visual Acuity
Interventions: DEVICE: Acuvue® Oasys MAX 1-Day|DEVICE: Dailies Total 1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of Mycobacterium w in Combination With Paclitaxel Plus Cisplatin in Advanced Non Small Cell Lung Cancer
Status: COMPLETED
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: Paclitaxel & Cisplatin|BIOLOGICAL: Mycobacterium w.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess Efficacy of Platelet-Rich Plasma in Androgenetic Alopecia
Status: UNKNOWN
Conditions: Androgenetic Alopecia|Alopecia|Hair Loss
Interventions: OTHER: PRP/Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Docetaxel in Node Positive Adjuvant Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Docetaxel|DRUG: 5-fluorouracil|DRUG: Doxorubicin|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GPIAG and Leicester Asthma and Dysfunctional Breathing (GLAD) Study: a Randomised Controlled Study
Status: COMPLETED
Conditions: Asthma|Respiratory
Interventions: OTHER: Physiotherapist
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Measure the Amount of Study Medicine in Blood in Adult Participants With COVID-19 and Severe Kidney Disease
Status: TERMINATED
Conditions: COVID-19
Interventions: DRUG: PF-07321332 (nirmatrelvir)/ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: P1101 and Anti-PD1 for After Curative Surgery of Hepatitis B-related Hepatocellular Carcinoma
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: P1101 (Ropeginterferon alfa-2b)|DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Venous Reflux Ablation Ulcer Trial
Status: COMPLETED
Conditions: Venous Leg Ulcer
Interventions: PROCEDURE: Early endovenous ablation|PROCEDURE: Delayed endovenous intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Viral Therapy in Treating Patient With Refractory Liver Cancer or Advanced Solid Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Malignant Solid Neoplasm|Hepatocellular Carcinoma
Interventions: OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacological Study|BIOLOGICAL: Recombinant Vesicular Stomatitis Virus-expressing Interferon-beta
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neuroablation Versus Neuromodulation Techniques for Treatment of Secondary Dystonia
Status: COMPLETED
Conditions: Secondary Dystonia
Interventions: PROCEDURE: Brain Lesioning|PROCEDURE: Combined anterior and posterior lumbosacral rhizotomy|DEVICE: Deep brain stimulation|DEVICE: Intra-thecal baclofen infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing Unimanual and Bimanual Mirror Therapy for Upper Limb Recovery Post Stroke
Status: COMPLETED
Conditions: Cerebral Vascular Accident (CVA)|Stroke
Interventions: BEHAVIORAL: Traditional Home Based Exercise Program|BEHAVIORAL: Unimanual Home Based Mirror Therapy Program|BEHAVIORAL: Bimanual Home Based Mirror Therapy Program
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy of EXPAREL in Comparison to Standard of Care for the Treatment of Post Operative Dental Implant Pain
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: PROCEDURE: EXPAREL and Local Anesthetics|PROCEDURE: Oral Opioid and Local Anesthetics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Open-Label Multicentre Long-Term Extension Study of Etanercept for Ankylosing Spondylitis
Status: COMPLETED
Conditions: Ankylosing Spondylitis
Interventions: DRUG: Enbrel (Etanercept)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diaphragmatic Breathing Exercises and Pelvic Floor Retraining in Children With Dysfunctional Voiding
Status: UNKNOWN
Conditions: Dysfunctional Voiding
Interventions: BEHAVIORAL: Diaphragmatic breathing|BEHAVIORAL: Standard urotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hepatic Steatosis and Pituitary Gland Failure, Evaluation by Nuclear Magnetic Resonance (NMR) Imaging
Status: COMPLETED
Conditions: Hepatic Steatosis|Pituitary Gland Failure
Interventions: OTHER: NMR|BIOLOGICAL: Blood samples|OTHER: fibroscan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Eight Weeks of Elbasvir/Grazoprevir in the Treatment of HCV Genotype 4
Status: COMPLETED
Conditions: Hepatitis C, Chronic
Interventions: DRUG: Elbasvir, Grazoprevir 50-100Mg Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Smoking Cessation Intervention During Low Dose CT (LDCT) Screening for Lung Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Smoking Cessation
Interventions: BEHAVIORAL: Questionnaires|PROCEDURE: Low Dose Computed Tomography Scan|OTHER: Shared Decision Making + Video|BEHAVIORAL: Cessation Counseling|BEHAVIORAL: Quitline|BEHAVIORAL: Pharmacotherapy Discussion|DRUG: Nicotine Patch|DRUG: Anti-Smoking Drug|BEHAVIORAL: Tobacco Treatment Program|OTHER: Carbon Monoxide (CO) Level Test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Topcon DRI OCT Triton With SS-OCT Angio Software Evaluation Study
Status: COMPLETED
Conditions: Fluorescein Angiography Imaging
Interventions: DEVICE: DRI OCT Triton with SS-OCT Angio software|DEVICE: Cirrus HD-OCT 5000|DEVICE: TRC-50DX
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phase II of Lenalidomide After Salvage Therapy in R/R Non-Hodgkin T-cell Lymphoma
Status: UNKNOWN
Conditions: Relapsed and/or Refractory Non-Hodgkin T-cell Lymphoma
Interventions: DRUG: Lenalidomide 25mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tamoxifen Versus Estradiol for Unscheduled Bleeding in Etonogestrel Implant Users, a Randomized Pilot Trial
Status: WITHDRAWN
Conditions: Vaginal Bleeding
Interventions: DRUG: Tamoxifen Citrate 10Mg Tab|DRUG: Estradiol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Trial of Tamoxifen and Letrozole in Recurrent and Persistent Squamous Cell Carcinoma of the Cervix
Status: UNKNOWN
Conditions: Uterine Cervical Neoplasms
Interventions: DRUG: Letrozole|DRUG: tamoxifen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dexmedetomidine for Reversal of Cocaine's Effects on the Heart
Status: COMPLETED
Conditions: Chest Pain|Acute Coronary Syndrome
Interventions: DRUG: Dexmedetomidine|DRUG: Normal Saline|DRUG: Intranasal cocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Aspheric Toric & Non-toric Aphakic Intraocular Lenses
Status: COMPLETED
Conditions: Aphakia|Cataract
Interventions: DEVICE: FY-60AD|DEVICE: NHT15, NHT30, & NHT53
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: An Observational Study to Evaluate the Clinical Effectiveness, Quality of Life, Safety and Tolerability of Tocilizumab (TCZ) in Patients With Rheumatoid Arthritis (RA) in Daily Clinical Practice
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Tocilizumab
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The ABSORB BTK (Below The Knee) Clinical Investigation
Status: TERMINATED
Conditions: Atherosclerosis|Peripheral Artery Disease|Peripheral Vascular Disease|PAD|Claudication|Critical Limb Ischemia|Lower Limb Disease|Peripheral Arterial Occlusive Disease|PAOD|PVD
Interventions: DEVICE: Everolimus Eluting BVS
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: DIA_CENTRAL:T2D Treatment Pattern in Central Europe
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Empagliflozin|DRUG: Sodium Glucose Transporter 2 inhibitor|DRUG: Dipeptidyl-peptidase 4 inhibitor|DRUG: Glucagon-like peptide 1 agonist
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Cryopreserved Human Umbilical Cord as a Meningeal Patch in Fetoscopic Spina Bifida Repair
Status: RECRUITING
Conditions: Spina Bifida; Fetus|Myelomeningocele|Myeloschisis
Interventions: DEVICE: NEOX Cord 1K applied fetoscopically
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Platelet Reactivity in Acute Non-disabling Cerebrovascular Events
Status: COMPLETED
Conditions: Stroke|Ischemic Attack, Transient
Interventions: DRUG: Ticagrelor and Acetylsalicylic acid|DRUG: Clopidogrel and Acetylsalicylic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hypofractionated Radiotherapy Versus Conventional Radiotherapy in Diffuse Brainstem Glioma in Children
Status: COMPLETED
Conditions: Pediatric Brain Stem Glioma
Interventions: RADIATION: Hypofractionated radiotherapy|RADIATION: Conventional arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Conventional Follow-up Versus Mobile App For Post-Operative ACL Reconstruction Patients
Status: UNKNOWN
Conditions: Anterior Cruciate Ligament (ACL) Tear
Interventions: DEVICE: mobile app|OTHER: conventional in-person
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison Between Platelet-rich Fibrin and Steroid for Intra-articular Injection for Sacroiliac Joint Dysfunction
Status: COMPLETED
Conditions: Low Back Pain
Interventions: BIOLOGICAL: intra-articular Platelet rich fibrin and lidocaine|DRUG: methylprednisolone acetate and lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Roxithromycin on Quality of Life and Physiological Outcomes in Bronchiectasis
Status: COMPLETED
Conditions: Quality of Life|Respiratory Function Tests
Interventions: DRUG: Roxithromycin 300 MG|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A First in HumanTrial to Evaluate The Safety, Tolerability, And Pharmacokinetics Of PF-06755347
Status: TERMINATED
Conditions: Healthy|Primary Immune Thrombocytopenia|Polyradiculoneuropathy, Chronic Inflammatory Demyelinating
Interventions: DRUG: PF-06755347 intravenous healthy participant|DRUG: Placebo intravenous healthy participant|DRUG: PF-06755347 subcutaneous healthy participant|DRUG: Placebo subcutaneous healthy participant|DRUG: PF-06755347 subcutaneous ITP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Efficacy, Safety and Tolerability of AIN457 in Patients With Active Overuse Tendinopathy
Status: COMPLETED
Conditions: Tendinopathy
Interventions: DRUG: secukinumab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Bimatoprost/Timolol Fixed Combination in Patients With Glaucoma or Ocular Hypertension
Status: COMPLETED
Conditions: Ocular Hypertension
Interventions: DRUG: bimatoprost/timolol fixed combination
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Ro 31-8959 Plus Zidovudine (AZT) Versus AZT Plus Zalcitabine (ddC) Versus Ro 31-8959 Plus AZT Plus ddC
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Saquinavir|DRUG: Zidovudine|DRUG: Zalcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Getting Kids With Osgood Schlatter Back to Performing Without Pain
Status: RECRUITING
Conditions: Osgood-Schlatter Disease
Interventions: BEHAVIORAL: Tailored progressive loading and return to sport|BEHAVIORAL: Pain guided activity
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Thin Strut Sirolimus-eluting Stent in All Comers Population vs Everolimus-eluting Stent
Status: COMPLETED
Conditions: Coronary Stenosis
Interventions: DEVICE: SUPRAFLEX|DEVICE: XIENCE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Characters of Epiretinal Membranes in Patients With Previous Vitrectomy for Retinal Detachment
Status: COMPLETED
Conditions: Rhegmatogenous Retinal Detachment of Both Eyes (Diagnosis)
Interventions: PROCEDURE: Surgery|DEVICE: Vitrectomy machine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy of Alkalinized Lidocaine Compared to Remifentanil on the Incidence of Coughing During Emergence of Anesthesia
Status: COMPLETED
Conditions: Cough|Anesthesia
Interventions: DRUG: Remifentanil|DRUG: Alkalinized lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: In Vivo Effects of Fibrinogen Concentrate (FC) Versus Cryoprecipitate on the Neonatal Fibrin Network Structure After Cardiopulmonary Bypass (CPB)
Status: COMPLETED
Conditions: Hemostasis
Interventions: DRUG: Fibrinogen Concentrate (FC)|DRUG: Cryoprecipitate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluation of the Safety and Performance Characteristics of Mesofiller Aox for the Correction of Mild and Moderate Facial Wrinkles.
Status: COMPLETED
Conditions: Skin Aging|Skin Wrinkling
Interventions: DEVICE: mesofiller aox
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Neoadjuvant Hepatocellular Carcinoma Study of Camrelizumab in Combination With Apatinib and Oxaliplatin
Status: NOT_YET_RECRUITING
Conditions: Hepatocellular Carcinoma Resectable
Interventions: DRUG: Apatinib Mesylate|DRUG: Camrelizumab|DRUG: Oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Psychosocial Consequences of the Screening of Von Hippel Lindau Diseases for Patients Operated for a hémangioblastoma of Nervous Centrasl System
Status: COMPLETED
Conditions: Hemangioblastoma (HB) of the Central Nervous System (CNS)
Interventions: OTHER: evaluation of anxiety with psychosocial scales
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Combination of Oral WX-671 Plus Capecitabine vs. Capecitabine Monotherapy in First-line Her2-negative Metastatic Breast Cancer
Status: COMPLETED
Conditions: Metastatic Breast Cancer
Interventions: DRUG: WX-671|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Metformin in Patients With PCOS and Predictors of Poor Ovarian Response Ongoing In-vitro Fertilization
Status: TERMINATED
Conditions: Infertility|PCOS|Prognosis for Poor Response
Interventions: DRUG: Metformin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Different Obturation Techniques
Status: COMPLETED
Conditions: Apical Periodontitis|Postoperative Pain|Endodontically Treated Teeth
Interventions: OTHER: Single Visit Non Surgical Root Canal Treatment Protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Regional Analgesia After Cesarean Section
Status: COMPLETED
Conditions: Cesarean Section|Pain, Postoperative|Pain, Neuropathic
Interventions: PROCEDURE: TAP (transversus abdominis plane block)|PROCEDURE: QLB (quadratus lumborum block)|DEVICE: Stimuplex Ultra 360 needle|DRUG: Ropivacaine|DRUG: Paracetamol|PROCEDURE: subarachnoid anesthesia|PROCEDURE: PCA (patient controlled analgesia)|DRUG: Metamizol|DRUG: Ketoprofen|DRUG: Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Intravenous Fluid Therapy in Acute Migraine Attacks
Status: UNKNOWN
Conditions: Migraine Disorders|Headache|Acute Pain
Interventions: OTHER: Bolus fluid administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Physiotherapeutic Interventions on Quality of Life in Patients With Chronic Low Back Pain. (Study 2)
Status: UNKNOWN
Conditions: Chronic Low Back Pain|Physiotherapy|Quality of Life|Range of Motion|Pain Intensity
Interventions: OTHER: Physioterapy intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Rivanna Ultrasound for Neuraxial Block
Status: COMPLETED
Conditions: Analgesia
Interventions: DEVICE: Rivanna Accuro US Device|OTHER: Palpation|PROCEDURE: Neuraxial Analgesia|PROCEDURE: Spinal Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Implementation of Nursing Demand Management as a Factor for Improvement in a Primary Care Emergency Center.
Status: ACTIVE_NOT_RECRUITING
Conditions: Nurse's Role|Disease, Acute
Interventions: OTHER: nursing procedure for acute health problems of low complexity
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Comparative Study Evaluating Performance of Celliant Fibers on Tissue Oxygenation
Status: COMPLETED
Conditions: Transcutaneous Oxygen Tension
Interventions: DEVICE: Celliant|DEVICE: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Trial to Evaluate the Efficacy and Safety of a New Full Length Recombinant Human FVIII for Hemophilia A
Status: COMPLETED
Conditions: Blood Coagulation Disorders|Hemophilia A
Interventions: BIOLOGICAL: Recombinant Factor VIII (BAY81-8973)|BIOLOGICAL: Recombinant Factor VIII (Kogenate FS, BAY14-2222)|BIOLOGICAL: Recombinant Factor VIII (BAY81-8973)|BIOLOGICAL: Recombinant Factor VIII (BAY81-8973)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study To Assess Changes In The Number Of Nerves In The Skin At The Site Where Where Tanezumab Is Injected
Status: COMPLETED
Conditions: Osteoarthritis Pain|Chronic Low Back Pain|Pain Due to Interstitial Cystitis
Interventions: OTHER: placebo|BIOLOGICAL: tanezumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Assessing Long Term Safety and Tolerability of PXT3003 in Patients With Charcot-Marie-Tooth Disease Type 1A
Status: ACTIVE_NOT_RECRUITING
Conditions: Charcot-Marie-Tooth Disease, Type IA
Interventions: DRUG: PXT3003
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Femoral Remodeling Following Total Hip Arthroplasty With OMNI Apex Modular™ and OMNI Apex ARC™ Stem Compared to Competitive Designs
Status: COMPLETED
Conditions: Osteoarthritis, Hip
Interventions: DEVICE: OMNI Apex Modular™ Hip Device|DEVICE: OMNI Apex ARC™ Hip Device
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phase 1 Study in Diabetes Mellitus(Fed)
Status: COMPLETED
Conditions: Diabetes|Diabete Mellitus
Interventions: DRUG: HUC2-344|DRUG: HUC2-344-R1, HUC2-344-R2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: C2 Esophageal Squamous Epithelium Dysplasia
Status: NOT_YET_RECRUITING
Conditions: Esophageal Squamous Epithelium Dysplasia
Interventions: DEVICE: C2 CryoBalloonTM Ablation System.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Lifestyle moDIfCation Study
Status: UNKNOWN
Conditions: Healthy
Interventions: BEHAVIORAL: Promotion of stair climbing|BEHAVIORAL: Promotion of a low-salt soup alternative for the 'soup of the day'|BEHAVIORAL: Promotion of a low-fat alternative for the butter croissants|BEHAVIORAL: Exchange of the basket positions of butter and margarine in the UMC staff restaurant between convenient and harder to reach locations
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: LUSZ Treatment Efficacy in Hospitalized COVID-19 Patients
Status: RECRUITING
Conditions: COVID-19|Hospitalized COVID-19 Patients
Interventions: DRUG: Lopinavir / Ritonavir|DRUG: Remdesivir (RDV)|DRUG: Tocilizumab|OTHER: Corticosteroid Therapy-enhanced Standard Care (CTSC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study of SHP620 (Maribavir) in Healthy Adults
Status: COMPLETED
Conditions: Cytomegalovirus (CMV)
Interventions: DRUG: Digoxin|DRUG: Maribavir|DRUG: Dextromethorphan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Selective Depletion of CD45RA+T Cells From Allogeneic Peripheral Blood Stem Cell Grafts for the Prevention of GVHD
Status: TERMINATED
Conditions: Graft Versus Host Disease|Leukemia|Myelodysplastic Syndromes
Interventions: DRUG: Fludarabine Phosphate|DRUG: Tacrolimus|DRUG: Thiotepa|RADIATION: Total-Body Irradiation (TBI)|OTHER: Magnetic Affinity Cell Sorting|PROCEDURE: Peripheral Blood Stem Cell Transplantation|PROCEDURE: Allogeneic Hematopoietic Stem Cell Transplantation|BIOLOGICAL: T Cell-Depleted Hematopoietic Stem Cell Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radiation Therapy With and Without Combination Chemotherapy in Patients With Resected Anaplastic Oligodendroglioma
Status: COMPLETED
Conditions: Brain and Central Nervous System Tumors
Interventions: DRUG: lomustine|DRUG: procarbazine hydrochloride|DRUG: vincristine sulfate|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of Telerehabilitation-Based Exercises in Elderly People
Status: UNKNOWN
Conditions: Telerehabilitation|Elderly People|Social Isolation
Interventions: OTHER: Telerehabilitation|OTHER: Exercise brochure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Nevirapine vs Ritonavir-boosted Lopinavir in ART Naive HIV-infected Adults in a Resource Limited Setting
Status: COMPLETED
Conditions: HIV-1 Infection
Interventions: DRUG: nevirapine|DRUG: ritonavir-boosted Lopinavir|DRUG: Tenofovir/emtricitabine|DRUG: Zidovudine/lamivudine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open, Non-Comparative Study of Intravenous and Oral Fluconazole in the Treatment of Acute Cryptococcal Meningitis
Status: COMPLETED
Conditions: Meningitis, Cryptococcal|HIV Infections
Interventions: DRUG: Fluconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Damask Rose Essential Oil Aromatherapy on Dental Anxiety and Pain on Children
Status: NOT_YET_RECRUITING
Conditions: Dental Anxiety
Interventions: OTHER: Damask Rose Essential Oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Measuring and Improving the Safety of Test Result Follow-Up
Status: COMPLETED
Conditions: Lung Cancer|Breast Cancer|Colon Cancer|Bladder Cancer|Hepatocellular Cancer
Interventions: BEHAVIORAL: SAFER TRACKS Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Evaluation of the Role of Endoscopic Ultrasound Guided Gastric Botulinum Toxin Injection in the Treatment of Obesity.
Status: UNKNOWN
Conditions: Endoscopy
Interventions: DEVICE: endoscopic ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mix and Match Heterologous Prime-Boost Study Using Approved COVID-19 Vaccines
Status: ACTIVE_NOT_RECRUITING
Conditions: Covid19
Interventions: BIOLOGICAL: BBIBP-CorV - Inactivated SARS-CoV-2 vaccine (Vero cell)|BIOLOGICAL: Ad26.COV2.S (Recombinant, replication-incompetent adenovirus serotype 26 (Ad26) vector encoding a full-length and stabilized SARS-CoV-2 spike protein),|BIOLOGICAL: Placebo - Normal saline (0.9% sodium chloride solution)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Phase 2 Study of Belimumab Administered Subcutaneously to Subjects With Systemic Lupus Erythematosus (SLE)
Status: TERMINATED
Conditions: Systemic Lupus Erythematosus
Interventions: DRUG: Belimumab 100 mg SC|DRUG: Belimumab 100 mg SC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Norwegian Randomized Trial on Indocyanine Green Cholangiography Utility for Laparoscopic Cholecystectomy, Prestudy
Status: RECRUITING
Conditions: Gall Stone|Cholecystitis
Interventions: PROCEDURE: Direct gallbladder injection of ICG intraoperatively|PROCEDURE: Intravenous injection 2.5 mg|PROCEDURE: Intravenous injection and direct gallbladder injection|PROCEDURE: Intravenous injection 5 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Fasting Study of Topiramate Sprinkle Capsules 25 mg and Topamax® Sprinkle Capsules 25 mg
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Topiramate Sprinkle Capsules 25 mg|DRUG: Topamax® Sprinkle Capsule 25 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Cross-over Study of the Efficacy and Safety of SierraSil Joint Formula 14 in Osteoarthritis of the Knee
Status: COMPLETED
Conditions: Osteoarthritis of the Knee
Interventions: DIETARY_SUPPLEMENT: SierraSil Joint Formula 14|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Initiation of Hydrocortisone for the Treatment of Septic Shock
Status: COMPLETED
Conditions: Septic Shock
Interventions: DRUG: Hydrocortisone|DRUG: saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of LX102 Gene Therapy in Patients With Neovascular Age-related Macular Degeneration (nAMD) (VENUS)
Status: RECRUITING
Conditions: Neovascular Age-Related Macular Degeneration
Interventions: GENETIC: LX102 subretinal injection|BIOLOGICAL: Aflibercept intravitreal injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Study to Evaluate Overall Response in Patients With Higher Risk Myelodysplastic Syndromes (MDS) Treated With Azacitidine With or Without Deferasirox.
Status: TERMINATED
Conditions: High Risk MDS
Interventions: DRUG: Azacitidine|DRUG: Azacitidine plus Deferasirox
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Assessing the Safety, Tolerability, and Pharmacokinetics of SEP-363856 in Japanese Male and Female Subjects With Schizophrenia in 2 Parts (Part 1 and 2).
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: SEP-363856
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Anetumab Ravtansine as 2nd Line Treatment for Malignant Pleural Mesothelioma (MPM)
Status: COMPLETED
Conditions: Mesothelioma
Interventions: DRUG: Anetumab ravtansine (BAY94-9343)|DRUG: Vinorelbine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dietary Lipids, Energy Expenditure and Obesity Biomarkers
Status: COMPLETED
Conditions: Obesity
Interventions: DIETARY_SUPPLEMENT: Group 1 - diet rich in n-3 and n-6 PUFA|DIETARY_SUPPLEMENT: Group 2 - diet rich in MUFA|DIETARY_SUPPLEMENT: Group 3 - Placebo group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of MK-1167 in Participants With Alzheimer's Disease Dementia Taking Stable Donepezil Treatment (MK-1167-007)
Status: ACTIVE_NOT_RECRUITING
Conditions: Alzheimer's Disease
Interventions: DRUG: MK-1167|DRUG: Donepezil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative of Effects of Sublingual Misoprostol and Infusion Oxytocin in Reduction of Bleeding at Cesarean
Status: UNKNOWN
Conditions: Bleeding Intraoperative
Interventions: DRUG: Misoprostol
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of FLOSEAL for Hemostasis in Total Knee Arthroplasty
Status: COMPLETED
Conditions: Knee Replacement Surgery|Osteoarthritis
Interventions: PROCEDURE: Standard of Care|DRUG: FLOSEAL Hemostatic Matrix + Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness and Side Effects of Pegylated Interferon Alpha-2a (Pegaferon®) Plus Ribavirin in the Patients With Chronic Hepatitis C
Status: COMPLETED
Conditions: Hepatitis C
Interventions: DRUG: Pegylated Interferon alpha 2a + Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of HICT and LIIT on Functional Strength and Weight Efficacy in Overweight and Obese Females
Status: COMPLETED
Conditions: Overweight and Obesity
Interventions: OTHER: High intensity circuit training|OTHER: Low intensity interval training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Improving the Sleep and Circadian Rhythms of Mechanically Ventilated Patients
Status: COMPLETED
Conditions: Critical Illness|Sleep Deprivation|Respiratory Failure|Sleep Disorders, Circadian Rhythm
Interventions: BEHAVIORAL: Sleep and circadian rhythm promotion|BEHAVIORAL: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Concurrent Chemoradiotherapy(CRT) in Locally Advanced(LA) SCCHN vs Cetuximab With Radiotherapy (RT) After Neoadjuvant Chemotherapy
Status: UNKNOWN
Conditions: Carcinoma, Squamous Cell of Head and Neck
Interventions: DRUG: Cetuximab|RADIATION: radiation|DRUG: Docetaxel|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antepartum Chronic Epidural Therapy (ACET) to Improve Blood Flow to the Uterus, Placenta and Baby in Pre-Eclampsia and Intrauterine Growth Restriction
Status: COMPLETED
Conditions: Pre-Eclampsia|Fetal Growth Retardation
Interventions: DRUG: Epidural ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Life Enhancing Alcohol-management Program
Status: ACTIVE_NOT_RECRUITING
Conditions: Alcohol Use, Unspecified|Homelessness|Harm Reduction|Community Based Participatory Research
Interventions: BEHAVIORAL: LEAP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Neurologic Signatures of Chronic Pain Disorders
Status: COMPLETED
Conditions: Chronic Pain|Chronic Migraine|Fibromyalgia
Interventions: DRUG: flunarizine and/or pregabalin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Prevention of Cardiovascular Disease and Mortality in Patients With Psoriasis or Psoriatic Arthritis
Status: RECRUITING
Conditions: Psoriasis|Psoriatic Arthritis|Psoriatic Conditions|Cardiovascular Diseases
Interventions: OTHER: Care Coordinator Model
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Adults Nutrition as a Protective or Health-risk Factor
Status: COMPLETED
Conditions: Nutritional Status|Nutrient Deficiency|Micronutrient Deficiency|Vitamin D Deficiency|Vitamin B 12 Deficiency|Folic Acid Deficiency|Iron-deficiency|Thyroid Diseases|Diet
Interventions: DIAGNOSTIC_TEST: Assessement of nutritional status|DIAGNOSTIC_TEST: Thyroid size
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Trial of XRD-0394, a Kinase Inhibitor, in Combination With Palliative Radiotherapy in Advanced Cancer Patients
Status: COMPLETED
Conditions: Metastasis|Locally Advanced Solid Tumor|Recurrent Cancer
Interventions: DRUG: XRD-0394|RADIATION: Palliative radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of WCK 5107 Alone and in Combination With Cefepime
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: WCK 5107 250 mg to 2000 mg|DRUG: Cefepime 2000 mg|DRUG: WCK 5107 1000/2000 mg with Cefepime 2000 mg combination|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Impact of Activity Breaks on Cognitive Function, Adiposity and Fitness in Preschoolers
Status: COMPLETED
Conditions: Physical Activity|Obesity|Children|Cardiovascular|High Intensity Interval Training|Cognition
Interventions: BEHAVIORAL: MOVI intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: ERTU-SODIUM: Study on the Effects of Ertugliflozin on Sodium Storage, Interstitial Volume, and Plasma Volume in HFrEF
Status: RECRUITING
Conditions: Heart Failure With Reduced Ejection Fraction|Congestion
Interventions: DRUG: Ertugliflozin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Human-Centered SH+ Trial for Earthquake Survivors
Status: TERMINATED
Conditions: Grief Disorder, Prolonged
Interventions: BEHAVIORAL: Beyond Quake: A Human-Centered SH+ Randomized Controlled Trial for Earthquake Survivors
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Comparison of Cangrelor, Tirofiban and Prasugrel in Patients With STEMI Referred for Primary PCI.
Status: COMPLETED
Conditions: Coronary Artery Disease|STEMI - ST Elevation Myocardial Infarction
Interventions: DRUG: Cangrelor|DRUG: Tirofiban|DRUG: Prasugrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Brentuximab for Newly Diagnosed Hodgkin Disease
Status: COMPLETED
Conditions: Hodgkin Lymphoma
Interventions: DRUG: Brentuximab Vedotin|DRUG: Doxorubicin|DRUG: Vincristine|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Acceptability of PRO 2000 Vaginal Gel in HIV Uninfected Women in India
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: PRO 2000/5 Gel (P)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Use of Traditional Chinese Medicine (Ren Shen Yang Rong Tang) Against Microinflammation in Hemodialysis Patients: A Quasi-randomized Controlled Trial
Status: COMPLETED
Conditions: Immune Dysfunction
Interventions: DRUG: Add R-S-Y-R-T (500 mg 3 times per day) for 6 months|DRUG: Routine western medicine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Epoetin Alfa in Treating Patients With Anemia Who Are Undergoing Chemotherapy for Cancer
Status: TERMINATED
Conditions: Anemia|Fatigue|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: Weekly procrit dosing|DRUG: Interval Dosing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Family, Responsibility, Education, Support, and Health for Families With a Child With Autism
Status: RECRUITING
Conditions: Autism Spectrum Disorder|Obesity, Childhood|Autism
Interventions: BEHAVIORAL: PBT-A|BEHAVIORAL: Health Education (HE)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Crucumin Effects on the Immune System in Osteoarthritis Patients
Status: UNKNOWN
Conditions: Osteoarthritis
Interventions: DRUG: Crucumin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Observational Safety Study of Menactra® Administered Under Standard Health Care Practice in the Russian Federation
Status: COMPLETED
Conditions: Meningitis|Meningococcal Meningitis|Meningococcal Infections
Interventions: BIOLOGICAL: Meningococcal (Groups A, C, Y and W 135) Polysaccharide Diphtheria Toxoid Conjugate Vaccine|BIOLOGICAL: Meningococcal (Groups A, C, Y and W 135) Polysaccharide Diphtheria Toxoid Conjugate Vaccine|BIOLOGICAL: Meningococcal (Groups A, C, Y and W 135) Polysaccharide Diphtheria Toxoid Conjugate Vaccine
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: An Efficacy and Safety Study of Gevokizumab in Treating Active Ulcers of Pyoderma Gangrenosum
Status: TERMINATED
Conditions: Pyoderma Gangrenosum
Interventions: DRUG: gevokizumab|DRUG: Placebo|DRUG: gevokizumab open-label
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: FLAT Study: First Line Ablation Therapy for Treatment of Paroxysmal Atrial Fibrillation (RAAFT)
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DEVICE: RF ablation|DRUG: anti-arrhythmic drug therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of "Kangaroo Mother Care" on Premature Infants Physiological Outcomes
Status: COMPLETED
Conditions: Premature Neonate
Interventions: OTHER: Kangaroo care approach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pro-Active Genetic Testing in Patients With Solid Tumors, Inherit Study
Status: COMPLETED
Conditions: Breast Carcinoma|Digestive System Neoplasm|Malignant Brain Neoplasm|Malignant Central Nervous System Neoplasm|Malignant Female Reproductive System Neoplasm|Malignant Genitourinary System Neoplasm|Malignant Head and Neck Neoplasm|Malignant Musculoskeletal Neoplasm|Malignant Solid Neoplasm|Metastatic Malignant Neoplasm of Unknown Primary|Skin Carcinoma
Interventions: PROCEDURE: Biospecimen Collection|OTHER: Genetic Counseling|OTHER: Genetic Testing|OTHER: Survey Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: GraftJacket Versus Tendon Interposition for Trapeziometacarpal Osteoarthritis
Status: COMPLETED
Conditions: Osteoarthrosis of the Carpometacarpal Joint of the Thumb
Interventions: PROCEDURE: GraftJacket|PROCEDURE: Tendon Interposition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of an Educational Multimedia Tool Versus Routine Care for the Uptake of Postpartum LARC in High-Risk Pregnancies
Status: ACTIVE_NOT_RECRUITING
Conditions: Pregnancy, High Risk|Contraception
Interventions: BEHAVIORAL: Decision Aid|BEHAVIORAL: Routine Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Comparison of Laparoscopic Cholecystectomy Versus Ultrasonic Dissection Assisted Minilaparotomy Cholecystectomy
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: PROCEDURE: Minilaparotomy vs laparoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study to Assess the Immunogenicity and Reactogenicity of High Versus Standard Dose TIV
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Fluzone High-Dose|BIOLOGICAL: Fluzone (standard dose)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Eradication of Helicobacter Pylori With a Lactobacillus Reuteri Strain Plus Proton Pump Inhibitor
Status: COMPLETED
Conditions: Helicobacter Pylori Infection
Interventions: OTHER: L.Reuteri
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Early Versus Delayed Double-guidewire Technique in Difficult Biliary Cannulation. (DFG)
Status: COMPLETED
Conditions: Catheterization|Cholangiopancreatography|Endoscopic Retrograde Cholangiography|Biliary Cannulation|Difficult Biliary Cannulation|Double-guidewire Technique
Interventions: PROCEDURE: Double-guidewire cannulation technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT