pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Video-Assisted Surgery Followed by Radiation Therapy in Treating Patients With Stage I Non-small Cell Lung Cancer and Poor Heart and Lung Function
Status: COMPLETED
Conditions: Lung Cancer
Interventions: PROCEDURE: adjuvant therapy|PROCEDURE: diagnostic thoracoscopy|PROCEDURE: therapeutic thoracoscopy|PROCEDURE: video-assisted surgery|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Using Telerehabilitation Tools to Deliver Quality Therapy to Patients Under Infective Isolation Precautions
Status: UNKNOWN
Conditions: Deconditioning, Isolation Precautions
Interventions: DEVICE: Telerehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Integration of HPV Vaccination and HPV-based Cervical Screening Into ARV Clinics: the H2VICTORY Trial
Status: NOT_YET_RECRUITING
Conditions: HPV Infection
Interventions: BIOLOGICAL: HPV vaccine|DIAGNOSTIC_TEST: HPV testing|BIOLOGICAL: HAV vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of IMM-101 in Combination With Radiation Induced Tumour Necrosis in Colorectal Cancer
Status: COMPLETED
Conditions: Metastatic Colorectal Cancer
Interventions: BIOLOGICAL: Mycobacterium obuense|RADIATION: SBRT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigate the Clinical Responses of Ethosuximide in Patients With Treatment-Resistant Depression.
Status: TERMINATED
Conditions: Depressive Disorder, Treatment-Resistant
Interventions: DRUG: Ethosuximide|DRUG: Placebo|DRUG: Escitalopram
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: RENAL: TNF-alpha Inhibitor for Improving Renal Dysfunction and Primary Graft Dysfunction After Lung Transplant
Status: ENROLLING_BY_INVITATION
Conditions: Lung Transplant; Complications
Interventions: DRUG: Etanercept Injection [Enbrel]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Transversus Abdominis Plane Block in Iliac Crest harvest-is it Beneficial?
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: PROCEDURE: local infiltration and TAP block|PROCEDURE: local infiltration only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Corazon de la Familia (Heart of the Family)
Status: COMPLETED
Conditions: Risk Reduction Behavior|Diabetes Mellitus, Type 2|Cardiovascular Diseases
Interventions: BEHAVIORAL: Family-focused intervention arm|BEHAVIORAL: Individual-focused intervention arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Smart Living Homes: GATEKEEPER System With Patients With Cancer and Dementia in Cyprus
Status: UNKNOWN
Conditions: Neoplasms|Cancer|Dementia
Interventions: DEVICE: GATEKEEPER
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Low Rate Fluoroscopy to Reduce Radiation Dose During Coronary Angiography and Intervention
Status: COMPLETED
Conditions: Stable Angina|Unstable Angina|Acute Coronary Syndrome
Interventions: RADIATION: 15 FPS|RADIATION: 7.5 FPS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Role of Mineralocorticoid Receptor in Diabetic Cardiovascular Disease
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus|Vascular Disease
Interventions: DRUG: Spironolactone|DRUG: Hydrochlorothiazide + potassium|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Test the Drug Darolutamide Along With the Drugs Leuprolide Acetate and Exemestane in Patients With Recurrent Ovarian Granulosa Cell Tumors
Status: SUSPENDED
Conditions: Adult Ovarian Granulosa Cell Tumor
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Chest Radiography|PROCEDURE: Computed Tomography|DRUG: Darolutamide|DRUG: Exemestane|DRUG: Leuprolide Acetate|PROCEDURE: Magnetic Resonance Imaging|PROCEDURE: Positron Emission Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of AD-MSCs Plus Calpocitriol Ointment and PSORI-CM01 Granule in Psoriasis Patients
Status: COMPLETED
Conditions: Mesenchymal Stromal Cells|Psoriasis|Drug Effect|Drug Toxicity
Interventions: DRUG: Calcipotriol ointment|DRUG: PSORI-CM01 Granule|BIOLOGICAL: adipose-derived multipotent mesenchymal stem cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Onivyde and 5-FU in Combination With Xilonix for Pancreatic Cancer With Cachexia
Status: COMPLETED
Conditions: Pancreatic Cancer|Cachexia|Weight Loss
Interventions: DRUG: Xilonix plus Onivyde and 5FU
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dehydroepiandrosterone (DHEA) in Systemic Lupus Erythematosus (SLE) for Coronary Artery Disease (CAD) Prevention
Status: COMPLETED
Conditions: Systemic Lupus Erythematosus
Interventions: DRUG: Dehydroepiandrosterone (DHEA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Olanzapine in Combination With a Mood Stabilizer vs Mood Stabilizer Alone, in Mixed Bipolar Patients
Status: COMPLETED
Conditions: Bipolar I Disorder
Interventions: DRUG: olanzapine|DRUG: placebo|DRUG: divalproex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: APL-101 Study of Subjects With NSCLC With c-Met EXON 14 Skip Mutations and c-Met Dysregulation Advanced Solid Tumors
Status: RECRUITING
Conditions: Solid Tumors|Advanced Cancer|Renal Cancer|Gastric Cancer|Gastroesophageal Junction Adenocarcinoma|NSCLC|Lung Cancer|Brain Tumor|Glioblastoma Multiforme|EGFR Gene Mutation|MET Amplification|HGF|Thyroid Cancer|Pancreatic Cancer|Colon Cancer|MET Alteration|MET Fusion|Exon 14 Skipping
Interventions: DRUG: APL-101 Oral Capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Exercises on Pain, Functional Disability and Lumbar Stability in Patients With Low Back Pain
Status: COMPLETED
Conditions: Exercise
Interventions: OTHER: exercise with ball|OTHER: exercise without ball
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Early Intervention for Impairments Identified During Comprehensive Geriatric Assessment in Patients With Bladder Cancer
Status: TERMINATED
Conditions: Bladder Cancer
Interventions: OTHER: Targeted Interventions for Impairments Identified During Geriatric Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: PARCT: Trial of Atezolizumab in Relapsed/Refractory Cutaneous T Cell Lymphoma (CTCL)
Status: TERMINATED
Conditions: Lymphoma, T-Cell, Cutaneous|Mycosis Fungoides/Sezary Syndrome
Interventions: DRUG: Atezolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess YH003 in Combination With Pebolizumab and Albumin Paclitaxel Injection in Subjects With Unresectable/Metastatic Mucosal Melanoma
Status: RECRUITING
Conditions: Mucosal Melanoma
Interventions: DRUG: YH003|DRUG: Pembrolizumab|DRUG: albumin paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of FCX-013 Plus Veledimex for the Treatment of Moderate to Severe Localized Scleroderma (Morphea)
Status: TERMINATED
Conditions: Morphea|Scleroderma, Localized|Scleroderma
Interventions: GENETIC: FCX-013|DRUG: veledimex
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Smartphone Application on the Quality of Bowel Preparation for Colonoscopy
Status: RECRUITING
Conditions: Colonoscopy|Bowel Preparation|Quality|Smartphone Application
Interventions: PROCEDURE: APP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effect of Vitamin C and E Therapy on Restless Leg Syndrome in Patients With End Stage Renal Disease on Haemodialysis
Status: UNKNOWN
Conditions: Restless Legs Syndrome|End Stage Renal Disease
Interventions: DRUG: Ascorbic acid|DRUG: Tocopherol|DRUG: Placebo capsule|DRUG: Placebo capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Performance and Safety of the Globe® Mapping and Ablation System With the GPS™ Module for the Treatment of Atrial Fibrillation
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DEVICE: Globe Mapping and Ablation System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Tobacco Cessation Care for Cancer Patients by Automated Interactive Outreach
Status: RECRUITING
Conditions: Cancer|Tobacco Dependence|Tobacco Use Cessation
Interventions: BEHAVIORAL: CareConnect|OTHER: AutoReach|PROCEDURE: Biospecimen samples
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Camrelizumab, Apatinib and Nab-paclitaxel as Second-line Treatment in Advanced Gastric Cancer
Status: UNKNOWN
Conditions: Advanced Gastric Cancer
Interventions: DRUG: Camrelizumab, Apatinib and Nab-paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nolatrexed Dihydrochloride Compared With Doxorubicin in Treating Patients With Recurrent or Unresectable Liver Cancer
Status: COMPLETED
Conditions: Liver Cancer
Interventions: DRUG: doxorubicin hydrochloride|DRUG: nolatrexed dihydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: VIsual Cerebral ConnecTivity On Functional Magnetic Resonance Imaging in Patients With Hereditary REtinal Dystrophies
Status: RECRUITING
Conditions: Vision Functional Brain Networks in Patients With Hereditary Retinal Dystrophies
Interventions: DEVICE: IRMf-r (séquence resting state)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Adenosine 2A Receptor Antagonism and AIH in ALS
Status: RECRUITING
Conditions: ALS
Interventions: DRUG: Consume 20mg of istradefylline|OTHER: Low Oxygen therapy|DRUG: Placebo counterpart to the istradefylline drug|OTHER: SHAM counterpart to low oxygen therapy.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Intra-articular Delivery of tgAAC94 in Inflammatory Arthritis Subjects
Status: COMPLETED
Conditions: Arthritis, Rheumatoid|Arthritis, Psoriatic|Ankylosing Spondylitis
Interventions: GENETIC: tgAAC94 gene therapy vector|GENETIC: tgAAC94 gene therapy vector|GENETIC: tgAAC94 placebo|GENETIC: tgAAC94 gene therapy vector|GENETIC: tgAAC94 gene therapy vector|GENETIC: tgAAC94 gene therapy vector|GENETIC: tgAAC94 gene therapy vector
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Motivational Interviewing and Cognitive Behavioral Therapy-based Intervention for Cardiovascular Disease Prevention Amongst American Indians With Diabetic and Depressive Symptoms
Status: COMPLETED
Conditions: Cardiovascular Diseases|Diabetes Mellitus, Type 2|Depression|Dysthymic Disorder
Interventions: BEHAVIORAL: Motivational Interviewing/Cognitive Behavioral-based Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Motec Versus Remotion Total Wrist Arthroplasty - A Prospective Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-rheumatoid Wrist Arthritis
Interventions: PROCEDURE: Motec total wrist arthroplasty|PROCEDURE: Remotion total wrist arthroplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Precision Spinal Cord Stimulation With Artisan Paddle Electrode
Status: TERMINATED
Conditions: Back Pain|Chronic Pain|Pain in Leg, Unspecified
Interventions: DEVICE: Precision Spinal Cord Stimulation System|DEVICE: Artisan Surgical Lead
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Safety and Activity of Eculizumab in Pediatric Participants With Relapsing Neuromyelitis Optica Spectrum Disorder
Status: TERMINATED
Conditions: Neuromyelitis Optica|Neuromyelitis Optica Spectrum Disorder
Interventions: DRUG: Eculizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Community-Acquired Methicillin Resistant Staphylococcus Aureus Colonization in Pregnant Women and Infections in Newborns
Status: UNKNOWN
Conditions: Staphylococcus Aureus Infection
Interventions: OTHER: CA-MRSA Decolonization
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Corneal Flap Thickness Planed vs Measured After LASIK by Using Tree Different Systems Cut
Status: TERMINATED
Conditions: Refractive Errors
Interventions: PROCEDURE: LASIK|PROCEDURE: LASIK|PROCEDURE: LASIK
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Effectiveness of Stromal Vascular Fraction (SVF) and Platelets Rich Plasma (PRP) in Osteoarthritis
Status: NOT_YET_RECRUITING
Conditions: Osteoarthritis
Interventions: DEVICE: Stromal Vascular Fraction infiltration|PROCEDURE: Plattelet Rich Plasma infiltration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Biomarkers of Endometrial Receptivity
Status: RECRUITING
Conditions: IVF|Infertility Treatment|Fertility Disorders|Embryo Transfer
Interventions: DIAGNOSTIC_TEST: Cervical mucus will be collected from patients undergoing IVF|DIAGNOSTIC_TEST: Cervical mucus will be collected from patients undergoing transfer of cryopreserved embryos
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of TRC105 With Abiraterone and With Enzalutamide in Prostate Cancer Patients Progressing on Therapy
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: TRC105|DRUG: Abiraterone|DRUG: Enzalutamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Intravenous to Oral Antibiotic Switch in Uncomplicated Staphylococcus Aureus Bacteraemia
Status: RECRUITING
Conditions: Staphylococcus Aureus Bacteremia
Interventions: DRUG: Tab. Trimethoprim-sulfamethoxazole, Tab. Clindamycin, Tab. Cephalexin, or Tab. Linezolid|DRUG: IV Cloxacillin, IV Cefazolin, IV Vancomycin, or IV Ceftaroline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A First-in-Human Study of SON-DP in Participants With Relapsed/Refractory Intolerant to Standard of Care Therapies for Advanced/Metastatic Solid Tumors
Status: RECRUITING
Conditions: Solid Tumor|Breast Cancer|Pancreatic Cancer|Ovarian Cancer|Colorectal Cancer
Interventions: DRUG: SON-DP
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Dynamic and Rigid Tape Application on the Asymmetry of the Lower Limbs
Status: COMPLETED
Conditions: Muscle Weakness
Interventions: OTHER: Dynamic tape|OTHER: Rigid tape|OTHER: Sham tape
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sensitivity Diagnosing Traumatic Knee Injuries With and Without Injection of Blue Dye Into the Knee Joint
Status: COMPLETED
Conditions: Traumatic Knee Arthrotomy
Interventions: PROCEDURE: Saline Load Test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Learning and Retention of Tracheal Intubation by Medical Students: Comparison of Standard Intubation Teaching Against Video-guided Intubation Teaching.
Status: COMPLETED
Conditions: Endotracheal Intubation
Interventions: PROCEDURE: Endotracheal intubation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: GEM 1.5 mg b.i.d. to 4.5 mg b.i.d. Versus Lorazepam in GAD (0777-026)
Status: COMPLETED
Conditions: Anxiety Disorder
Interventions: DRUG: MK0777
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Treating Earthquake in Nepal Trauma (TENT) Trial 2016
Status: UNKNOWN
Conditions: Post-traumatic Stress Disorder (PTSD)
Interventions: BEHAVIORAL: Narrative Exposure Therapy|BEHAVIORAL: Control Focused Behavioural Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Study Using Placenta Derived Decidual Stromal Cells for Graft Versus Host Disease
Status: UNKNOWN
Conditions: Graft vs Host Disease
Interventions: BIOLOGICAL: Early Decidual stromal cell therapy|BIOLOGICAL: Late Decidual stromal cell therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Manipulative and Massage Therapy in the Lower Thoracic and Cervical Spine in Subjects With Fibromyalgia Syndrome
Status: UNKNOWN
Conditions: Fibromyalgia
Interventions: OTHER: Manipulative and Massage Therapy|OTHER: Exercise Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Stroke Rehabilitation Program Based on a Powered Lower Extremity Exoskeleton in Chile
Status: COMPLETED
Conditions: Stroke
Interventions: DEVICE: Robot-assisted training with a lower extremity powered exoskeleton (H3 Exoskeleton, Spain)|BEHAVIORAL: Conventional gait rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Midazolam With Meperidine and Dexmedetomidine vs. Midazolam With Meperidine and Propofol for Sedation During ERCP
Status: COMPLETED
Conditions: Complication
Interventions: DRUG: Midazolam®|DRUG: "Meperidine" (pethidine®)|DRUG: Propofol®|DRUG: Dexmedetomidine (Precedex®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nicotinamide in the Treatment of Psoriasis
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: Calcipotriol plus Nicotinamide|DRUG: Calcipotriol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of MK-1697 in Participants With Advanced Solid Tumors (MK-1697-001)
Status: TERMINATED
Conditions: Neoplasms|Colorectal Neoplasms|Head and Neck Neoplasms
Interventions: BIOLOGICAL: MK-1697
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Pharmacokinetic Study of MRG-201 in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: MRG-201|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Does Local Morphine Add to Local Anesthetics in Serratus Anterior Plane Block Has a System Analgesic Effect?
Status: COMPLETED
Conditions: Postoperative Complications
Interventions: DRUG: Morphine Sulfate|DRUG: Bupivacaine Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Safety and Pharmacokinetics Study of CPL500036 Compound in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: CPL500036 compound|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective Studies of the Use of Self Hypnosis, Acupuncture and Osteopathic Manipulation on Muscle Tension in Children With Spastic Cerebral Palsy
Status: COMPLETED
Conditions: Spastic Cerebral Palsy
Interventions: PROCEDURE: Self Hypnosis|PROCEDURE: Acupuncture|PROCEDURE: Osteopathic Manipulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Medtronic Transcatheter Aortic Valve Replacement (TAVR) Low Risk Bicuspid Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Bicuspid Aortic Valve
Interventions: DEVICE: Medtronic TAVR Systems
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: AVE8062 in Combination With Platinum-taxane Doublet in Advanced Solid Tumor
Status: COMPLETED
Conditions: Neoplasms
Interventions: DRUG: OMBRABULIN (AVE8062)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Impact of Dose and Dosing Frequency of AZD8848 on the Response on Biomarkers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: AZD8848|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Trial of the Pharmacokinetics, Safety, and Tolerability of Subcutaneous Gamunex® in Primary Immunodeficiency
Status: COMPLETED
Conditions: Immunologic Deficiency Syndrome
Interventions: BIOLOGICAL: Immune Globulin Intravenous (Human)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Brivanib (BMS-582664) in Patients With Liver Cancer and Mild, Moderate or Severe Liver Dysfunction
Status: COMPLETED
Conditions: Carcinoma, Hepatocellular
Interventions: DRUG: Brivanib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Multilac Baby on Fecal Calprotectin Levels of Colicky Babies
Status: UNKNOWN
Conditions: Infantile Colic
Interventions: DRUG: Simethicone Solution|DIETARY_SUPPLEMENT: Multilac Baby
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Dynavax Heplisav B in Healthcare Workers Previously Vaccinated With 3-dose Vaccine Who Failed to Demonstrate Seroprotection
Status: WITHDRAWN
Conditions: Hepatitis B Virus
Interventions: BIOLOGICAL: Adjuvanted Hepatitis B Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of PEEP and Trendelenburg on Ultrasound Size of Internal Jugular and Subclavian Veins
Status: COMPLETED
Conditions: Ventilated Patient in Intensive Care|Management of the Expiratory End-expiratory Pressure (PEEP) and Body Position
Interventions: BEHAVIORAL: Patient's position
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Non-Comparative Study To Evaluate Changes In FMD After Quinapril Therapy In Hypertensive Women
Status: COMPLETED
Conditions: Menopause|Hypertension
Interventions: DRUG: quinapril|PROCEDURE: Laser Doppler imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Relapse Prevention Study Of Desvenlafaxine Succinate Sustained Release In Outpatients With Major Depressive Disorder
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: Desvenlafaxine succinate sustained release 50 mg|DRUG: Desvenlafaxine succinate sustained release 25 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Triclosan-antibacterial Sutures Efficacy on the Incidence of Surgical Site Infection in Clean-contaminated Wounds
Status: RECRUITING
Conditions: Surgical Site Infection|Surgical Wound|Surgical Wound Infection
Interventions: DRUG: coated vicryl plus|DRUG: Vicryl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Trial of the Ovicidal Activity of Three Head Lice Products (NeutraLice Lotion®, NeutraLice Advance® and Moov Head Lice Solution®) After a Single Application
Status: COMPLETED
Conditions: Head Lice
Interventions: DRUG: NeutraLice Lotion|DRUG: NeutraLice Advance Solution|DRUG: Moov Head Lice Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Long-term Efficacy and Safety of Repeated Ofatumumab Treatment Courses in RA Patients Who Previously Received Ofatumumab or Placebo in Trial Hx-CD20-403
Status: TERMINATED
Conditions: Arthritis, Rheumatoid
Interventions: DRUG: ofatumumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Safety, Tolerability and Pharmacokinetics of JNJ-42847922 in Healthy Japanese Male Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: JNJ-42847922, 5 mg|DRUG: JNJ-42847922, 20 mg|DRUG: JNJ-42847922, 40 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Baby-Led Weaning and Traditional Complementary Feeding Education on Infant Development
Status: COMPLETED
Conditions: Growth|Infant Development|Complementary Feeding|Nutrition, Healthy|Anemia, Iron Deficiency|Obesity, Infant
Interventions: OTHER: Baby-Led Weaning (BLW)|OTHER: Traditional Complementary Feeding (TCF)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Infant-Maternal Partnership and Cognitive Training Study for Preterm Infants
Status: NOT_YET_RECRUITING
Conditions: Child Development|Infant Development|Infant, Premature, Diseases
Interventions: BEHAVIORAL: Finger puppet|BEHAVIORAL: Bookworm reading intervention training and routine EDI care.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Between Nicotine Replacement Products and Nicorette® Gum
Status: COMPLETED
Conditions: Tobacco Dependence
Interventions: DRUG: Nicotine|DRUG: Nicorette® (Nicotine Gum)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study the Efficacy and Safety of PTK 0796 in Patients With Complicated Skin and Skin Structure Infection (CSSSI)
Status: COMPLETED
Conditions: Infectious Skin Disease|Bacterial Skin Disease
Interventions: DRUG: PTK 0796|DRUG: Linezolid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Safety and Efficacy of Pembrolizumab and Chemotherapy in Participants With Newly Diagnosed Classical Hodgkin Lymphoma (cHL) (MK-3475-C11/KEYNOTE-C11)
Status: COMPLETED
Conditions: Classical Hodgkin Lymphoma
Interventions: BIOLOGICAL: Pembrolizumab|DRUG: Doxorubicin|DRUG: Vinblastine|DRUG: Dacarbazine|DRUG: Bleomycin|DRUG: Etoposide|DRUG: Cyclophosphamide|DRUG: Vincristine|DRUG: Procarbazine|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combined Coronary and Cerebral Angiography and Intervention for Coronary and Cerebrovascular Atherosclerosis
Status: UNKNOWN
Conditions: Coronary Stenosis|Cerebral Stenosis
Interventions: OTHER: simultaneous coronary and cerebral intervention|OTHER: staged coronary and cerebral intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rumination Focused Cognitive Behavioral Therapy for Major Depression and Recurrent Depression
Status: COMPLETED
Conditions: Depression|Recurrent Depression
Interventions: BEHAVIORAL: Group based rumination focused CBT|BEHAVIORAL: Group based CBT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Efficacy and Safety Between Medical Radiation Protectants (FORRAD®) and Trolamine (Biafine) for the Management of Radiation Dermatitis in Patients With Nasopharyngeal Carcinoma Receiving IMRT
Status: UNKNOWN
Conditions: Nasopharyngeal Neoplasms|Radiodermatitis
Interventions: DRUG: Medical Radiation Protectants (FORRAD®)|DRUG: Trolamine (Biafine)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Brachial Plexus Block in Post-Op Pain Control After Distal Upper Extremity Fracture: A Prospective Randomized Study
Status: COMPLETED
Conditions: Pain
Interventions: PROCEDURE: Brachial Plexus Nerve Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Artesunate-amodiaquine and Artemether-lumefantrine for Uncomplicated Malaria in South Kivu, DR Congo
Status: COMPLETED
Conditions: Malaria
Interventions: DRUG: Amodiaquine-Artesunate (ASAQ)|DRUG: Artemether-Lumefantrine (AL)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study on the Gut Microbial Mechanism of Negative Symptoms of Schizophrenia
Status: UNKNOWN
Conditions: Negative Symptom|Schizophrenia|Amisulpride|Gut Microbiomes
Interventions: DRUG: Amisulpride
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Trial of High Dose Influenza Vaccine in Long Term Care Setting
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: High Dose Inactivated Influenza Vaccine|BIOLOGICAL: Standard Dose Inactivated Influenza Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Qoyangnuptu: Qoyangnuptu Intervention (QI) App
Status: NOT_YET_RECRUITING
Conditions: Mental Health Wellness 1
Interventions: BEHAVIORAL: QI App Users|BEHAVIORAL: Parents/Guardians of QI App Users
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Just-in-time Training for Teaching Neonatal Endotracheal Intubation
Status: COMPLETED
Conditions: Intubation|Education|Simulation Training
Interventions: OTHER: Simulation-based just-in-time training|OTHER: Video training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Photobiomodulation Therapy on Low Back Pain
Status: COMPLETED
Conditions: Low Back Pain
Interventions: DEVICE: Placebo PBMT|DEVICE: PBMT active
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Efficacy and Safety Trial of Intravenous Zoledronic Acid in Infants Less Than One Year of Age, With Severe Osteogenesis Imperfecta
Status: COMPLETED
Conditions: Osteogenesis Imperfecta
Interventions: DRUG: Zoledronic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Incidental Auditory Category Training for Language Learning
Status: TERMINATED
Conditions: Healthy|Language
Interventions: BEHAVIORAL: Incidental training|BEHAVIORAL: Explicit training|BEHAVIORAL: Classroom training|BEHAVIORAL: Classroom and incidental training|BEHAVIORAL: Classroom and explicit training
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effects of Nanomicelles Curcumin on Glycemic Control, Serum Lipid Profile ,Blood Pressure and Anthropometric Measurements in Patients With Metabolic Syndrome
Status: UNKNOWN
Conditions: Metabolic Syndrome
Interventions: DIETARY_SUPPLEMENT: nanomicielle curcumin|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluating the Safety and Immunogenicity of EnvSeq-1 and CH505 M5 gp120 Envs Adjuvanted With GLA-SE in Healthy, HIV-Uninfected Adults
Status: COMPLETED
Conditions: HIV Infections
Interventions: BIOLOGICAL: CH505TF|BIOLOGICAL: CH505w53|BIOLOGICAL: CH505w78|BIOLOGICAL: CH505 M5|BIOLOGICAL: GLA-SE adjuvant|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: RCVS: The Rational Approach to Diagnosis and Treatment
Status: WITHDRAWN
Conditions: Reversible Cerebral Vasoconstriction Syndrome
Interventions: DIAGNOSTIC_TEST: TCD- cerebral blood flow velocities|BEHAVIORAL: Headache pain score|OTHER: Neurological examination|DIAGNOSTIC_TEST: Repeat Neuroimaging|DRUG: Nimodipine|DRUG: Verapamil ER
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exploratory Clinical Study of Neutrophil Activation Probe (NAP) for Optical Molecular Imaging in Human Lungs
Status: COMPLETED
Conditions: Acute Lung Injury
Interventions: OTHER: Microdose of NAP
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Multiple Dose Study With Incremental Dosing to Evaluate the Safety, Tolerability, and Pharmacokinetics of Oral Doses of LEO 32731 in Healthy Male Japanese Subjects.
Status: COMPLETED
Conditions: Psoriasis Vulgaris
Interventions: DRUG: LEO 32731|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Outcome Measures of Patients Receiving Acute Renal ThErapy Study
Status: COMPLETED
Conditions: End Stage Kidney Disease|End Stage Renal Disease|Acute Kidney Injury
Interventions: DEVICE: Intermittent Renal Replacement Therapy using the Tablo Hemodialysis System|DEVICE: Intermittent Renal Replacement Therapy using Conventional Hemodialysis Systems
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Edible Insects: Good for the Gut and the Globe
Status: ACTIVE_NOT_RECRUITING
Conditions: Irritable Bowel Syndrome
Interventions: DIETARY_SUPPLEMENT: Chitin Fiber|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of Propofol Infusion on Total Antioxidant Status During Tourniquet-Induced Ischemia-Reperfusion Injury
Status: COMPLETED
Conditions: Total Knee Arthroplasty|Tourniquet-Induced Ischemia-Reperfusion Injury
Interventions: DRUG: Propofol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Sitagliptin in Type 2 Diabetes Mellitus With Inadequate Glycemic Control (MK0431-118)
Status: TERMINATED
Conditions: Diabetes Mellitus Non-insulin-dependent
Interventions: DRUG: sitagliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Polyvinylpyrrolidone-Sodium Hyaluronate Gel in Reducing Pain From Oral Mucositis in Young Patients With Cancer
Status: UNKNOWN
Conditions: Brain and Central Nervous System Tumors|Chordoma|Kidney Cancer|Leukemia|Lymphoma|Mucositis|Neuroblastoma|Pain|Sarcoma|Unspecified Childhood Solid Tumor, Protocol Specific
Interventions: DRUG: polyvinylpyrrolidone-sodium hyaluronate gel
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pharmacokinetics of Oral Capsule in Healthy Japanese vs. Caucasian Subjects
Status: COMPLETED
Conditions: Safety Issues|Pharmacokinetics
Interventions: DRUG: HTL0018318|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Tolerance Comparison Between Subconjunctival Injection of Triamcinolone and Intravitreal Implant of Dexamethasone for the Treatment of Inflammatory Macular Edema
Status: COMPLETED
Conditions: Inflammatory Macular Edema
Interventions: DRUG: Dexamethasone|DRUG: Triamcinolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Estimation of Central Venous Pressure by Echocardiography in Intubated Children in Pediatric Intensive Care
Status: UNKNOWN
Conditions: Echocardiography in Intubated Children in Pediatric Intensive Care|Intubation Complication
Interventions: DIAGNOSTIC_TEST: Estimation of central venous pressure by echocardiography in intubated children in pediatric intensive care
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Feasibility of a Lateral Flow Urine LAM Test for Diagnosis of Tuberculosis in South Africa
Status: UNKNOWN
Conditions: Tuberculosis|Tuberculosis, Pulmonary|Tuberculosis, Miliary
Interventions: DEVICE: Alere "Determine" lateral-flow urine lipoarabinomannan assay|DEVICE: Alere "Clearview" ELISA urine LAM assay|DEVICE: Cepheid Xpert MTB/Rif assay
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Clinical Trial on the Efficacy and Safety of Sirolimus-Eluting Stent (MiStent® System)
Status: UNKNOWN
Conditions: Coronary Heart Disease
Interventions: DEVICE: MiStent|DEVICE: TIVOLI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of 0.5%, 0.1% & 0.01% Atropine Treatment to Both Eyes In Treatment of Myopia In Children
Status: UNKNOWN
Conditions: Myopia
Interventions: DRUG: Atropine Eye drops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Oral Titrated Misoprostol for Induction of Labour
Status: COMPLETED
Conditions: Labor, Induced
Interventions: DRUG: Misoprostol|DRUG: Misoprostol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic and PHarmacodynamic Analysis and Evaluation of Teriparatide (PTH 1-34) Between Sexes
Status: COMPLETED
Conditions: Stress Fracture
Interventions: DRUG: Teriparatide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Stroke Prophylaxis With Apixaban in Chronic Kidney Disease Stage 5 Patients With Atrial Fibrillation
Status: RECRUITING
Conditions: Chronic Kidney Diseases|Atrial Fibrillation|Stroke|Intracerebral Hemorrhage|Major Bleed|Cardiovascular Complication|Death|Kidney Transplant; Complications|Thromboses, Venous
Interventions: DRUG: Apixaban 2.5 milligram Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Ramelteon in Adults With Chronic Insomnia
Status: TERMINATED
Conditions: Chronic Insomnia
Interventions: DRUG: Ramelteon|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Supplementation of Vitamin D in Patients With Crohn's Disease
Status: UNKNOWN
Conditions: Crohn Disease|Vitamin D Deficiency|Fatigue|Sarcopenia|Muscle Weakness|Disorder of Bone Density and Structure, Unspecified
Interventions: DIETARY_SUPPLEMENT: Vitamin D|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of Therapeutic Hypothermia in Patients With ARDS
Status: RECRUITING
Conditions: Respiratory Distress Syndrome, Adult
Interventions: DEVICE: Hypothermia|DRUG: Neuromuscular Blocking Agents|DEVICE: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Estramustine, Docetaxel, and Carboplatin for Patients With Hormone Refractory Prostate Cancer Progressing After Mitoxantrone-Based Chemotherapy.
Status: COMPLETED
Conditions: Prostate Adenocarcinoma
Interventions: DRUG: Estramustine|DRUG: Docetaxel|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Immunogenicity of LP-98 Injection in Healthy Subjects
Status: COMPLETED
Conditions: Hiv
Interventions: DRUG: LP-98 injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Relugolix With Estradiol and Norethindrone Acetate in Women With Heavy Menstrual Bleeding Associated With Uterine Fibroids
Status: COMPLETED
Conditions: Uterine Leiomyoma|Uterine Fibroids
Interventions: DRUG: Relugolix|DRUG: Estradiol/norethindrone acetate|DRUG: Placebo for relugolix|DRUG: Placebo for E2/NETA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess Safety and Efficacy of Perampanel in Indian Participants as an Adjunctive Treatment in Partial Onset Seizures With or Without Secondary Generalized Seizures in Participants With Epilepsy Aged 12 Years or Older
Status: COMPLETED
Conditions: Partial Onset Seizures|Epilepsy
Interventions: DRUG: Perampanel
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Footcore Exercises on Navicular Drop and Plantar Pressure Distribution in Asymptomatic Individual With Flatfoot
Status: RECRUITING
Conditions: Flatfoot
Interventions: OTHER: Footcore exercises and conventional therapy|OTHER: conventional therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Pioglitazone in Participants With Inadequately Controlled Type 2 Diabetes Mellitus Treated With Stable Triple Oral Therapy
Status: COMPLETED
Conditions: Type II Diabetes Mellitus
Interventions: DRUG: Pioglitazone|DRUG: Metformin|DRUG: Sulfonylurea
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT