pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Efficacy and Safety of Intralesional Corticosterois in the Treatment of Vitiligo
Status: UNKNOWN
Conditions: Vitiligo
Interventions: DRUG: Triamcinolone Acetonide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PRP Injections for Genitourinary Syndrome of Menopause
Status: RECRUITING
Conditions: PRP|Sexual Function Disturbances|Genitourinary Syndrome of Menopause|Postmenopausal Symptoms|Vaginal Atrophy
Interventions: PROCEDURE: Injection of platelet-rich plasma|PROCEDURE: Injection of saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Cardiovascular Autonomic Function and Endogenous Pain Modulation
Status: UNKNOWN
Conditions: Fibromyalgia|Exercise|Pain|Autonomic Dysfunction|Physical Activity
Interventions: OTHER: Exercise|OTHER: Cognitive Task
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of Postoperative Healing After Conventional And Laser Assisted Frenectomy Operations
Status: COMPLETED
Conditions: Frenulum; Hypertrophy, Lip
Interventions: DEVICE: Gigaa Cheese 810 nm Diode Laser|PROCEDURE: Conventional Frenectomy Operation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of TC(Docetaxel and Carboplatin) Regimen With or Without Nimotuzumab in Recurrent Metastatic Oral Squamous Cell Carcinoma
Status: UNKNOWN
Conditions: Oral Squamous Cell Carcinoma
Interventions: DRUG: Nimotuzumab|DRUG: Docetaxel|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Placebo Controlled Study of VS-6063 in Subjects With Malignant Pleural Mesothelioma
Status: TERMINATED
Conditions: Malignant Pleural Mesothelioma
Interventions: DRUG: defactinib (VS-6063)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Using Counter Attitudinal Advocacy to Change Drinking Behavior
Status: UNKNOWN
Conditions: Alcohol Drinking|Alcohol Abuse
Interventions: BEHAVIORAL: Counter Attitudinal Advocacy|BEHAVIORAL: Personalized Normative Feedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Mental Practice in Post-stroke Subjects
Status: UNKNOWN
Conditions: Stroke Sequelae|Stroke
Interventions: OTHER: Physical practice|OTHER: Mental practice|OTHER: Videotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bilateral Ultrasound-Guided Transversus Abdominis Plane (Tap) Block and Erector Spinal Plane (Esp) Block
Status: COMPLETED
Conditions: Pain, Postoperative|Cesarean Section|Erector Spinae Plane Block|Transversus Abdominis Plane Block
Interventions: PROCEDURE: Procedure/Surgery: Transversus Abdominis Plane Block (TAPB)|PROCEDURE: Procedure/Surgery: Erector Spinae Plane Block (ESPB)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Left Atrial Appendage Occlusion Versus Novel Oral Anticoagulation for Stroke Prevention in Atrial Fibrillation
Status: RECRUITING
Conditions: Atrial Fibrillation|Stroke
Interventions: DEVICE: Left atrial appendage occlusion|DRUG: NOAC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Foreign Body Removal With the Assistance of Ultrasound Guidance and Methylene Blue Staining in Children
Status: COMPLETED
Conditions: Foreign Bodies|Ultrasound
Interventions: PROCEDURE: US guidance and MB staining
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Impact of Limited Compared With Intense Post-Operative Surveillance on Patient-Reported Outcomes in Patients With Stage II-III Soft Tissue Sarcoma of the Trunk and Extremities
Status: RECRUITING
Conditions: Stage II Soft Tissue Sarcoma of the Trunk and Extremities AJCC v8|Stage III Soft Tissue Sarcoma of the Trunk and Extremities AJCC v8|Stage IIIA Soft Tissue Sarcoma of the Trunk and Extremities AJCC v8|Stage IIIB Soft Tissue Sarcoma of the Trunk and Extremities AJCC v8
Interventions: PROCEDURE: Chest Radiography|PROCEDURE: Computed Tomography|PROCEDURE: Follow-Up|PROCEDURE: Follow-Up|PROCEDURE: Imaging Technique|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Acute Effect of Intensive Insulin Infusion on Intestinal Triglyceride-rich-lipoprotein-apoB48 Metabolism in Type 2 Diabetic Patients
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DIETARY_SUPPLEMENT: saline infusion|OTHER: euglycaemic hyperinsulinic clamp|DIETARY_SUPPLEMENT: infusion of Endolipide and heparin|OTHER: hyperglycaemic hyperinsulinic clamp
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Chemotherapy Combined With CIK Treating Colon Cancer
Status: COMPLETED
Conditions: Colorectal Cancer|Cytokine-induced Killer Cells|Postoperative Complications|Survival
Interventions: DRUG: Cytokine-induced killer cells+ FOLFOX4|DRUG: FOLFOX4
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I Dose-Escalation Trial of Clofarabine Followed by Escalating Doses of Fractionated Cyclophosphamide in Children With Relapsed or Refractory Acute Leukemias
Status: TERMINATED
Conditions: Myelodysplastic Syndrome|Acute Myeloid Leukemia|Myeloproliferative Disorders|Acute Lymphocytic Leukemia|Acute Promyelocytic Leukemia|Acute Leukemia|Chronic Myelogenous Leukemia|Myelofibrosis|Chronic Myelomonocytic Leukemia|Juvenile Myelomonocytic Leukemia
Interventions: DRUG: Clofarabine|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical, Biological and NMR Outcome Measures Study for Hereditary Inclusion Body Myopathy Due to Mutation of UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine Kinase Gene (GNE)
Status: COMPLETED
Conditions: HIBM
Interventions: OTHER: motor function and strength assessment|OTHER: NMR assessment|OTHER: 24h urine and serum collection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: EUS-RFA PANCARDINAL-1 Trial
Status: RECRUITING
Conditions: Pancreatic Ductal Adenocarcinoma (PDAC)
Interventions: DEVICE: Endoscopic Ultrasound (EUS)-Guided Radiofrequency Ablation (RFA)|DRUG: Neoadjuvant Chemotherapy (NAC)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Theta Burst Transcranial Magnetic Stimulation on Patients With Dysphagia After Stroke
Status: NOT_YET_RECRUITING
Conditions: Stroke|Dysphagia|Functional Near- Infrared Spectroscopy|Transcranial Magnetic Stimulation
Interventions: DEVICE: Theta burst transcranial magnetic stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: GYNECARE PROSIMA* Procedure Versus Modified Total Pelvic Floor Reconstructive Surgery for Uterine Prolapse Stage III
Status: UNKNOWN
Conditions: Uterine Prolapse|Stage III
Interventions: PROCEDURE: Procedure: TVH and GYNECARE PROSIMA* Pelvic Floor Repair System|PROCEDURE: Procedure: TVH and Modified Pelvic Floor Reconstruction Surgery with mesh
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Using Drug Augmentation to Treat Obsessive Compulsive Disorder Patients Who Did Not Respond to Previous Treatment
Status: COMPLETED
Conditions: Obsessive Compulsive Disorder
Interventions: DRUG: Clomipramine (fluoxetine plus clomipramine)|DRUG: Quetiapine (fluoxetine plus quetiapine)|DRUG: Placebo (fluoxetine plus placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of Pharmacokinetic(PK)/Pharmacodynamic(PD) Relationship of Monotherapy MORAb-004 in Metastatic Melanoma
Status: COMPLETED
Conditions: Metastatic Melanoma
Interventions: BIOLOGICAL: MORAb-004 (monoclonal antibody)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study to Evaluate Renal Hemodynamic Responses to Aliskiren in Patients With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Aliskiren|DRUG: Irbesartan|DRUG: Captopril
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Vision Restoration With a Collagen Crosslinked Boston Keratoprosthesis Unit
Status: COMPLETED
Conditions: Keratolysis
Interventions: DRUG: Riboflavin|DRUG: Dextran|DEVICE: UVA Light Source
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluating Buspirone to Treat Opioid Withdrawal
Status: RECRUITING
Conditions: Opioid Use Disorder|Opioid Withdrawal|Opioid Craving|Anxiety
Interventions: DRUG: Buspirone|DRUG: Lofexidine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1b Study of IV PRM151 in Patients With Idiopathic Pulmonary Fibrosis (IPF)
Status: COMPLETED
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: BIOLOGICAL: PRM-151|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Spa Therapy for Upper or Lower Limb Lymphoedema
Status: RECRUITING
Conditions: Lymphoedema|Breast Cancer|Malignant Disease|Gynaecological Cancer|Lymphoma|Prostate Cancer
Interventions: OTHER: Immediate spa treatment|OTHER: Late spa treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Ketamine and Magnesium in Post-operative Pain Control in Patients Treated With Opioids
Status: TERMINATED
Conditions: Chronic Pain
Interventions: DRUG: Ketamine plus Magnesium sulfate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I/II Study of Vaccination With Antigen Loaded Dendritic Cells (DCs) in Patients With Inoperable Stage III and Stage IV Melanoma
Status: TERMINATED
Conditions: Melanoma
Interventions: BIOLOGICAL: Dendritic cell application
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 3 Clinical Study of KHK 4827
Status: COMPLETED
Conditions: Psoriasis Vulgaris|Psoriatic Arthritis|Pustular; Psoriasis, Palmaris Et Plantaris|Psoriatic Erythroderma
Interventions: DRUG: KHK4827 140mg SC|DRUG: KHK4827 210mg SC
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Evaluation of Atomoxetine on Attention Deficit Hyperactivity Disorder (ADHD) Symptoms in Adolescents With Cannabis abusE
Status: TERMINATED
Conditions: Attention Deficit Hyperactivity Disorder|Cannabis Abuse
Interventions: DRUG: Atomoxetine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Clinical and Biochemical Effect of Therapeutic Massage on Fatigue and Insomnia in Women With Breast Cancer Receiving Radiation Therapy
Status: UNKNOWN
Conditions: Breast Cancer|Fatigue|Insomnia
Interventions: PROCEDURE: Therapeutic Massage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Potassium Reduction Initiative to Optimize RAAS Inhibition Therapy With Sodium Zirconium Cyclosilicate in Heart Failure
Status: TERMINATED
Conditions: Heart Failure
Interventions: DRUG: Sodium Zirconium Cyclosilicate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Albumin for Intracerebral Hemorrhage Intervention
Status: TERMINATED
Conditions: Intracerebral Hemorrhage
Interventions: DRUG: Albumin|DRUG: Placebo|PROCEDURE: Brain MRI with and without contrast
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Antihypertensive Efficacy and Safety of Approved Drugs in Japanese Patients With Essential Hypertension (Banyu Study)(0954A-302)
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: MK0954A, hydrochlorothiazide (+) losartan potassium|DRUG: Comparator: placebo, losartan, hydrochlorothiazide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of BCAA on Sleep
Status: RECRUITING
Conditions: Sleep Disorder|Traumatic Brain Injury
Interventions: DIETARY_SUPPLEMENT: Branched Chain Amino Acids|DIETARY_SUPPLEMENT: Rice Protein|DIETARY_SUPPLEMENT: Microcrystalline Cellulose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Neomycin on the Pharmacokinetics of Regorafenib
Status: COMPLETED
Conditions: Neoplasms
Interventions: DRUG: Regorafenib (Stivarga, BAY73-4506)|DRUG: Neomycin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Assess the Efficacy and Safety of SHR0302 Ointment in Adult Patients With Vitiligo
Status: TERMINATED
Conditions: Vitiligo
Interventions: DRUG: Low Dose SHR0302 Ointment BID|DRUG: High Dose SHR0302 Ointment BID|OTHER: Placebo Comparator: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: tDCS in Chronic Migraine With Medication Overuse (Edisom)
Status: COMPLETED
Conditions: Migraine Disorders|Medication Overuse Headache
Interventions: DEVICE: tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ranibizumab for Macular Edema Secondary to Branch Retinal Vein Occlusion in Patients With Fair Vision
Status: TERMINATED
Conditions: Branch Retinal Vein Occlusion|Macular Edema
Interventions: DRUG: Ranibizumab|DEVICE: Sham injection|PROCEDURE: Rescue laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Immune Response to Third Dose of COVID-19 Vaccine in Solid Organ Transplant
Status: COMPLETED
Conditions: COVID-19|SARS-CoV-2 Infection|Solid Organ Transplant|Vaccine Response Impaired
Interventions: BIOLOGICAL: Three doses of SARS-CoV-2 BNT162b2 vaccine (observational)|BIOLOGICAL: Two doses of CoronaVac and one dose of BNT162b2 SARS-CoV-2 vaccine (observational)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Recombinant Attenuated Salmonella Typhi Vaccine Vectors Producing Streptococcus Pneumoniae PspA
Status: COMPLETED
Conditions: Pneumonia
Interventions: BIOLOGICAL: Salmonella Typhi-vectored pneumonia vaccine|BIOLOGICAL: Salmonella Typhi-vectored pneumonia vaccine|BIOLOGICAL: Salmonella Typhi-vectored pneumonia vaccine|BIOLOGICAL: Salmonella Typhi-vectored pneumonia vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of Intramuscular Injections of ABBV-950 to Assess Adverse Events and Change in Disease Activity in Adult Participants With Upper Limb Spasticity
Status: TERMINATED
Conditions: Upper Limb Spasticity
Interventions: BIOLOGICAL: ABBV-950|BIOLOGICAL: BOTOX|DRUG: Placebo for ABBV-950
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase II, 5-way Cross-over Study to Evaluate the Pharmacodynamics of "Nexthaler" Dry Powder Inhaler in COPD Patients
Status: COMPLETED
Conditions: COPD
Interventions: DRUG: CHF 1535 NEXThaler 800/48|DRUG: CHF 1535 NEXThaler 200/12|DRUG: CHF 1535 NEXThaler PLACEBO|DRUG: CHF 1535 pMDI 200/12|DRUG: CHF1535 pMDI 800/48
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Investigating the Efficacy of Various Wound Closure Devices in Reducing Postoperative Wound Complications
Status: COMPLETED
Conditions: Joint Disease|Arthropathy
Interventions: DEVICE: Zipper surgical skin closure|OTHER: Monocryl + Dermabond|OTHER: Polyester mesh + Dermabond
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Conjugate Pneumococcal Vaccine in Ataxia Telangiectasia (AT)
Status: COMPLETED
Conditions: Ataxia Telangiectasia (AT)
Interventions: DRUG: Conjugated pneumococcal vaccine (Prevenar)
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: BASIC_SCIENCE
Clinical trial: Postoperative Oral Nutritional Supplementation After Major Gastrointestinal Surgery
Status: COMPLETED
Conditions: Gastric Cancer|Colon Cancer|Pancreatic Cancer|Duodenal Cancer|Biliary Cancer|Peptic Ulcer|Inflammatory Bowel Diseases
Interventions: DIETARY_SUPPLEMENT: oral nutritional supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Computer-Based Training for Cognitive Enhancement: Classroom Study
Status: COMPLETED
Conditions: Aging
Interventions: OTHER: Computerized Plasticity-Based Adaptive Cognitive Training|OTHER: Educational DVDs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intravenous Nutrition in Hospitalized Patients: Comparison of Two Oils
Status: COMPLETED
Conditions: Obstruction|Cancer|Ileus|Malnutrition|Surgery
Interventions: DRUG: Intralipid|DRUG: ClinOleic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Endoscopic Resection in Gastro-Esophageal Reflux Disease
Status: SUSPENDED
Conditions: GERD|Gastro Esophageal Reflux
Interventions: PROCEDURE: Endoscopic mucosal resection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vascular Effect of CIMICIFUGA RACEMOSA
Status: COMPLETED
Conditions: Postmenopausal Symptoms
Interventions: DRUG: Cimifuga Racemosa|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: COVID-19 VACCINE SAFETY AND EFFECTIVENESS
Status: UNKNOWN
Conditions: SARS-CoV-2 Infection
Interventions: BIOLOGICAL: ChAdOx1 nCoV-19 vaccine (AZD1222)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Fasting Free Fatty Acids and Fasting Glucose on 1st and 2nd Phase Insulin Secretion
Status: WITHDRAWN
Conditions: Healthy
Interventions: DRUG: Somatostatin|OTHER: Dextrose|DRUG: Insulin|OTHER: Intralipid
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Early Trial of Allogeneic Hematopoietic Stem Cell Transplantation for Patients Who Will Receive a Kidney Transplant From the Same Donor
Status: RECRUITING
Conditions: SIOD|Cystinosis|FSGS|SLE Nephritis|CKD Stage 4
Interventions: DRUG: Cyclophosphamide 1200 mg/Kg|DRUG: Fludarabine|DRUG: Cyclophosphamide 100 mg/Kg|RADIATION: Total Body Irradiation|DRUG: ATG|DRUG: Rituximab|DRUG: Melphalan|DEVICE: CliniMACS® TCR α/β Reagent Kit and CliniMACS® CD19 System|PROCEDURE: Kidney Transplant
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anti-PD-1 Antibody Plus Chidamide and Rituximab Regimen in Relapsed or Refractory DLBCL (PCR)
Status: NOT_YET_RECRUITING
Conditions: Relapsed or Refractory DLBCL
Interventions: DRUG: Anti-PD-1 Antibody Plus Chidamide and Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Analysis of Molecular Biomarkers in Periocular Adnexal Tumours
Status: RECRUITING
Conditions: Sebaceous Cell Tumor of Eyelid
Interventions: GENETIC: exome sequencing (retrospective) and exome and methylome sequencing (prospective)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Immunogenicity and Safety of Meningococcal Vaccine GSK134612 vs. Menactra® in Healthy Adolescent/Adults Aged 10-25 Years.
Status: COMPLETED
Conditions: Infections, Meningococcal
Interventions: BIOLOGICAL: Meningococcal vaccine 134612|BIOLOGICAL: Menactra®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Master Protocol to Assess Safety and Dose of First Time in Human Next Generation Engineered T Cells in NY-ESO-1 and/or LAGE-1a Positive Advanced Solid Tumors
Status: TERMINATED
Conditions: Neoplasms
Interventions: DRUG: GSK3901961|DRUG: GSK3845097|DRUG: GSK4427296|DRUG: Cyclophosphamide|DRUG: Fludarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Safety, and Tolerability Rollover Study of Eteplirsen in Subjects With Duchenne Muscular Dystrophy
Status: COMPLETED
Conditions: Duchenne Muscular Dystrophy (DMD)
Interventions: DRUG: AVI-4658 (Eteplirsen)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Utility of Intermittent Cryo-Compression Versus Traditional Icing Following Arthroscopic Rotator Cuff Repair
Status: RECRUITING
Conditions: Rotator Cuff Injuries|Cryotherapy Effect
Interventions: DEVICE: Cryo-compression|OTHER: Cryo-therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nasal High-flow Compared to Non-invasive Ventilation in Treatment of Acute Acidotic Hypercapnic Exacerbation of Chronic Obstructive Pulmonary Disease
Status: RECRUITING
Conditions: COPD Exacerbation Acute
Interventions: DEVICE: Respiratory support with nasal high-flow (NHF)|DEVICE: Respiratory support with non-invasive ventilation (NIV)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Three-dimensional Ultrasonography Thyroid Volume Measurement.
Status: UNKNOWN
Conditions: Thyroid|Thyroid Cancer|Thyroid Diseases|Graves Disease|Thyroid Goiter|Thyroid Adenoma
Interventions: DEVICE: BK 5000 Ultrasound Machine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: PictureRx: An Intervention to Reduce Latino Health Disparities
Status: COMPLETED
Conditions: Medication Adherence|Diabetes
Interventions: BEHAVIORAL: PictureRx card
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: To Evaluate the Efficacy and Safety of Hearticelgram®-AMI in Patients With Acute Myocardial Infarction.
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Myocardial Infarction
Interventions: BIOLOGICAL: Hearticellgram-AMI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dexmedetomidine Combined With Hydromorphone in Tonsillectomy and Adenoidectomy
Status: COMPLETED
Conditions: Agitated; State, Acute Reaction to Stress
Interventions: DRUG: Dexmedetomidine 0.5μg／kg|DRUG: Dexmedetomidine 1μg／kg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy of an Extract of Concentrated Korean Red Ginseng for Preventing Upper Respiratory Tract Infections
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DIETARY_SUPPLEMENT: Korean red ginseng|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluate the Safety, Tolerability, Immunogenicity and Efficacy of UB-311 in Mild Alzheimer's Disease (AD) Patients
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: BIOLOGICAL: UB-311|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: SBRT for Oligo-residual NSCLC After Treatment With PD-1/PD-L1 Immune Checkpoint Inhibitors
Status: RECRUITING
Conditions: NSCLC Stage IV
Interventions: DRUG: PD-1/PD-L1 inhibitors (alone or in combination with chemotherapy)|RADIATION: SBRT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Pharmacokinetics of Alpha-1 MP (Alpha1-proteinase Inhibitor (Human), Modified Process) in Participants With Alpha1-Antitrypsin Deficiency
Status: COMPLETED
Conditions: Alpha1-Antitrypsin Deficiency
Interventions: BIOLOGICAL: Alpha-1 MP
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Self-Administered 2-Hour Oral Glucose Tolerance Test
Status: RECRUITING
Conditions: Gestational Diabetes|Postpartum Disorder|Gestational Diabetes Mellitus in Pregnancy
Interventions: OTHER: Self-administered oral glucose tolerance test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: A Care Model for Elderly Hip-fractured Persons With Cognitive Impairment and Their Family Caregivers
Status: COMPLETED
Conditions: Hip Fractures|Cognitive Impairment
Interventions: BEHAVIORAL: family-centered care model
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Two Handed Jaw-thrust on Postoperative Sore Throat After Double-lumen Endotracheal Tube Insertion
Status: COMPLETED
Conditions: Lung Surgery
Interventions: PROCEDURE: Two-handed jaw thrust|PROCEDURE: Conventional intubation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of Efficacy and Frequency of Adverse Events of 1st Line Palliative Chemotherapy EOX and mDCF Regimens in Advanced HER2-negative Gastric Carcinoma
Status: COMPLETED
Conditions: HER2 Negative Gastric Cancer
Interventions: OTHER: EOX|OTHER: mDCF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Medtronic CoreValve Evolut R U.S. Clinical Study (Evolut 34R Addendum)
Status: COMPLETED
Conditions: Aortic Valve Stenosis
Interventions: DEVICE: CoreValve Evolut 34R TAVR system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I Study of Safety and Persistence of UC-781 Vaginal Microbicide
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: UC-781|DRUG: UC-781 placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: D-Cycloserine Augmentation of Behavior Therapy for Individuals With Body Dysmorphic Disorder
Status: COMPLETED
Conditions: Body Dysmorphic Disorder
Interventions: DRUG: d-cycloserine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Surgery in Patients With Idiopathic Macular Hole
Status: UNKNOWN
Conditions: Idiopathic Macular Hole|Surgery
Interventions: PROCEDURE: ILM peeling surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Focused Ultrasound for the Complex Patient
Status: RECRUITING
Conditions: Opioid Use Disorder|Chronic Back Pain|Anxiety
Interventions: DEVICE: low intensity focused ultrasound (LIFU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Paclitaxel With or Without Pazopanib Hydrochloride in Treating Patients With Persistent or Recurrent Ovarian Epithelial, Fallopian Tube, or Peritoneal Cavity Cancer
Status: COMPLETED
Conditions: Recurrent Fallopian Tube Carcinoma|Recurrent Ovarian Carcinoma|Recurrent Primary Peritoneal Carcinoma
Interventions: OTHER: Laboratory Biomarker Analysis|DRUG: Paclitaxel|DRUG: Pazopanib Hydrochloride|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: TCR-engineered T Cells in Solid Tumors (ACTengine IMA201-101)
Status: COMPLETED
Conditions: Solid Tumor|Cancer|Recurrent Solid Tumors|Refractory Solid Tumors
Interventions: BIOLOGICAL: IMA201 Product|DIAGNOSTIC_TEST: IMADetect®
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Active Class Space Metabolic Benefits Study
Status: COMPLETED
Conditions: Childhood Obesity
Interventions: BEHAVIORAL: Light-Intensity Condition|BEHAVIORAL: Moderate-Intensity Condition|BEHAVIORAL: High-Intensity Condition|BEHAVIORAL: Sedentary Condition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Ticagrelor Antiplatelet Therapy to Reduce Graft Events and Thrombosis
Status: COMPLETED
Conditions: Saphenous Vein Graft Disease
Interventions: DRUG: Aspirin|DRUG: Ticagrelor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Double-blind Study to Compare the Efficacy, Safety, and Immunogenicity of the Proposed Biosimilar Ustekinumab FYB202 to Stelara® in Patients With Moderate-to-Severe Plaque Psoriasis
Status: COMPLETED
Conditions: Plaque Psoriasis
Interventions: DRUG: FYB202 (Proposed ustekinumab biosimilar)|DRUG: Stelara® (Ustekinumab)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pancreatic Cancer Screening Through the Detection of Elastase-1 Combined With Other Examinations
Status: RECRUITING
Conditions: Pancreatic Ductal Adenocarcinoma|Pancreatic Diseases|Pancreatic Elastase 1|Pancreatic Neuroendocrine Tumor|Pancreatitis|Pancreatic Neoplasms
Interventions: DIAGNOSTIC_TEST: Pancreatic elastase-1 in blood serum
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of the Effect of Blood Stem Cell Transplant After Chemotherapy Alone in Patients With Fanconi Anemia
Status: TERMINATED
Conditions: Fanconi Anemia|Myelodysplastic Syndrome (MDS)|Acute Myelogenous Leukemia (AML)
Interventions: DRUG: Busulfan|DRUG: Fludarabine|DRUG: Cyclophosphamide|DRUG: Anti-Thymocyte Globulin (Rabbit)|DEVICE: The CliniMACS device|DRUG: G-CSF
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Research Study to Look at Long-term Treatment With a Medicine Called NNC6019-0001 for People Who Have Heart Failure Due to Transthyretin Amyloidosis
Status: RECRUITING
Conditions: Transthyretin Amyloid Cardiomyopathy (ATTR CM)
Interventions: DRUG: NNC6019-0001
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Korean Life-Style Modification Effects on Blood Pressure
Status: COMPLETED
Conditions: Prehypertension|Hypertension
Interventions: DRUG: Control group who are advised for proper life style modification by the physician such as regular exercise and healthy diet without active intervention.|DIETARY_SUPPLEMENT: Treatment group 1(Dietary intervention)|OTHER: Treatment group 2(dietary and exercise intervention)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Supplementary Vitamin B12 Effects on Elevated Homocysteine Levels of Vegetarians - Clinical Trial
Status: COMPLETED
Conditions: Vitamin B12 Deficiency
Interventions: DIETARY_SUPPLEMENT: Inactive lozenge|DIETARY_SUPPLEMENT: Methylcobalamin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Methadone Oxytocin Option
Status: COMPLETED
Conditions: Substance Abuse|Opioid Dependence|Methadone Treatment
Interventions: DRUG: Oxytocin|DRUG: Saline Nasal Spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Chronic Thermogenic Dietary Supplement Consumption
Status: COMPLETED
Conditions: Body Composition Changes|Body Weight Changes|Anthropometric Changes|Metabolism Changes|Hemodynamic Changes
Interventions: DIETARY_SUPPLEMENT: Thermogenic dietary supplement|DIETARY_SUPPLEMENT: Protein supplement|DIETARY_SUPPLEMENT: Placebo supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial Comparing Moviprep and Phosphoral as Bowel Prep Before Colonoscopy
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: bowel prep before endoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: L-Glutamine Therapy for Sickle Cell Anemia
Status: TERMINATED
Conditions: Sickle Cell Anemia|Thalassemia
Interventions: DRUG: L-Glutamine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neuromodulation for Prevention of Intensive Care Unit Acquired Weakness and Post Intensive Care Syndrome
Status: RECRUITING
Conditions: Muscle Atrophy|Muscle Weakness|Blood Flow
Interventions: DEVICE: Intervention Group|DEVICE: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study to Evaluate Safety, Tolerability and Pharmacokinetics of Multiple Rising of BEA 2180 BR in Japanese Healthy Male Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BEA 2180 BR - rising dose|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness and Safety of Pharmacopunture Therapy for Chronic Low Back Pain: A Pragmatic Randomized Controlled Trial
Status: COMPLETED
Conditions: Chronic Low-back Pain
Interventions: PROCEDURE: pharmacopuncture therapy|PROCEDURE: physical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess Vamorolone in Becker Muscular Dystrophy (BMD)
Status: RECRUITING
Conditions: Becker Muscular Dystrophy
Interventions: DRUG: Vamorolone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of RO5095932 in Patients With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus Type 2
Interventions: DRUG: RO5095932|DRUG: RO5095932|DRUG: metformin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cayenne Pepper Cataplasm - Effect Study
Status: COMPLETED
Conditions: Back Pain|Low Back Pain
Interventions: OTHER: Cayenne Pepper Cataplasm|OTHER: Placebo Cataplasm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: EVOlocumab for Early Reduction of LDL-cholesterol Levels in Patients With Acute Coronary Syndromes (EVOPACS)
Status: COMPLETED
Conditions: Acute Coronary Syndrome
Interventions: DRUG: Evolocumab 140 mg/mL|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Personalized Perioperative Analgesia Platform (PPAP) for Pediatric Spine Fusion Surgery (sIRB)
Status: RECRUITING
Conditions: PPAP|Spine Fusion
Interventions: DIAGNOSTIC_TEST: Preoperative Genotyping
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Iron Absorption From Infant Formula and Iron Drops in Infants (MJAU-studien)
Status: COMPLETED
Conditions: Infant|Dietary Supplements|Food, Fortified
Interventions: DIETARY_SUPPLEMENT: ferrous sulfate|OTHER: iron-fortified infant formula (12.4 mg iron/L)|OTHER: iron-fortified infant formula (2.3 mg iron/L)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Long-term Safety and Efficacy of Sirukumab in Participants With RA Completing Studies CNTO136ARA3002 or CNTO136ARA3003
Status: COMPLETED
Conditions: Arthritis, Rheumatoid
Interventions: DRUG: Sirukumab 100 mg|DRUG: Sirukumab 50 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficiency of Writing Endoscopic Reports by Artificial Intelligence and Physicians: a Randomized Controlled Trial
Status: UNKNOWN
Conditions: Gastrointestinal Disease
Interventions: OTHER: AI generated report|OTHER: physicians writing report
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Effects of Talocrural Joint Mobilizations in the Treatment of Subacute Lateral Ankle Sprains
Status: UNKNOWN
Conditions: Ankle Sprain
Interventions: OTHER: Mobilization therapy in addition to standard therapy|OTHER: Sham intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing of the PK, PD, Safety and Immunogenicity of HS-20090 and Xgeva® in Healthy Adults
Status: RECRUITING
Conditions: Healthy
Interventions: DRUG: HS-20090|DRUG: Xgeva®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Protective Role of N-acetylcisteine From Cisplatin-induced Ototoxicity in Patients With Head and Neck Cancer
Status: COMPLETED
Conditions: Cisplatin Adverse Reaction|Hearing Loss Ototoxic
Interventions: DRUG: N Acetylcysteine|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Tilelizumab Combined With Nab-Paclitaxel for High-Risk Non-Muscle-Invasive Urothelial Bladder Carcinoma Which is Not Completely Resectable: a Multi-center Study
Status: UNKNOWN
Conditions: High-Risk Non-Muscle Invasive Bladder Urothelial Carcinoma
Interventions: DRUG: Tislelizumab Nab paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: REmote Assessment and Dynamic Response Intervention
Status: COMPLETED
Conditions: Dementia|Alzheimer Disease|Relationship, Marital|Caregiver Stress Syndrome
Interventions: BEHAVIORAL: READyR A|BEHAVIORAL: READyR B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Inspiratory Flow Rates Achieved by the COPD Patients Through Breezhaler®, Ellipta® and Handihaler® Inhaler Devices
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive (COPD)
Interventions: DEVICE: Breezhaler®|DEVICE: Ellipta®|DEVICE: Handihaler®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preliminary Assessment of [18F]BL40 in PET/CT Scans
Status: NOT_YET_RECRUITING
Conditions: Diffuse Large B-cell Lymphoma|Multiple Myeloma|Mantle Cell Lymphoma|Marginal Zone Lymphoma|Chronic Lymphocytic Leukemia|Waldenström Macroglobulinemia
Interventions: DIAGNOSTIC_TEST: 18F-BL40 PET/CT|DIAGNOSTIC_TEST: 18F-FDG PET/CT|DIAGNOSTIC_TEST: Routine Blood Draw - Phase 1 only
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Atherogenic Risk Factors and Efficacy of Nutritional Treatment Among Adult Phenylketonuria Patients
Status: NOT_YET_RECRUITING
Conditions: Phenylketonurias|Nutritional and Metabolic Diseases
Interventions: DIAGNOSTIC_TEST: Ultrasound of the jugular veins|DIETARY_SUPPLEMENT: addition of phenylalanine-free protein substitutes
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Post-operative Pain in Short Versus Long Stitch for Laparotomy Closure
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: PROCEDURE: Short stitch|PROCEDURE: Long stitch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of a Newborn Simulator's Fidelity on Nursing Students' Level of Engagement in a Clinical Lactation Encounter
Status: WITHDRAWN
Conditions: Breastfeeding|Education, Nursing
Interventions: OTHER: Breastfeeding Simulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Safety and QoL of Trastuzumab With Lapatinib or Chemiotherapy in MBC and HER2+ Patients Refractory to Anti HER2 Therapies
Status: UNKNOWN
Conditions: Metastatic Breast Cancer
Interventions: DRUG: Lapatinib|DRUG: Trastuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Perclose Multi-Access Duplex Ultrasound (DUS) Study
Status: COMPLETED
Conditions: Arrhythmia
Interventions: DEVICE: Perclose ProGlide SMC System and/or Perclose ProStyle SMCR System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Metoprolol Succinate Extended Release Tablets 200 mg Under Fed Conditions
Status: COMPLETED
Conditions: Fed
Interventions: DRUG: Metoprolol Succinate ER Tablet 200 mg|DRUG: 'TOPROL-XL®' ER Tablets 200 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of a Cognitive Remediation Intervention Based on Virtual Reality for Promotion of Cognitive Functioning and Participation in Daily Life Among Persons With Affective Disorder
Status: UNKNOWN
Conditions: Affective Disorder
Interventions: OTHER: Intendu|OTHER: Paper and Pencil cognitive remediation training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT