pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: CoStar™ Paclitaxel-Eluting Coronary Stent Catheter System Evaluation
Status: COMPLETED
Conditions: Coronary Disease
Interventions: DEVICE: CoStar™ Paclitaxel-Eluting Coronary Stent with SRX catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Psychoeducation in Patients Who Diagnosed With Schizophrenia
Status: COMPLETED
Conditions: Quality of Life|Well-Being|Compliance, Treatment
Interventions: BEHAVIORAL: Group Psychoeducation that Focused on Social Skill Development
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BI 695501 Versus Humira in Patients With Active Crohn's Disease: a Trial Comparing Efficacy, Endoscopic Improvement, Safety, and Immunogenicity
Status: COMPLETED
Conditions: Crohn Disease
Interventions: DRUG: BI 695501|DRUG: HUMIRA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pembrolizumab + Chemotherapy in Newly Diagnosed PCNSL
Status: RECRUITING
Conditions: Lymphoma|Primary Central Nervous System Lymphoma
Interventions: DRUG: Pembrolizumab|DRUG: Methotrexate|DRUG: Temozolomide|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Effect of Tranexamic Acid on the Clinical Outcomes in Patients With Traumatic Brain Injury
Status: RECRUITING
Conditions: Traumatic Brain Injury
Interventions: DRUG: Tranexamic Acid (TXA)|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Xerotic Dermatitis in Aged People
Status: COMPLETED
Conditions: Itching Symptoms|Xerotic Dermatitis
Interventions: DEVICE: DC086|DEVICE: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Cadonilimab Plus Chemotherapy Following Short-Course Radiotherapy in Locally Advanced Rectal Cancer
Status: RECRUITING
Conditions: Locally Advanced Rectal Carcinoma
Interventions: DRUG: Cadonilimab Injection|RADIATION: Short-course radiotherapy|DRUG: Consolidation chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Interleukin 28B (rs12979860) Genotype on Virological Responses Chronic Hepatitis C Treatment
Status: COMPLETED
Conditions: Hepatitis C|Hepatitis C Relapse
Interventions: DRUG: Pegylated Interferon α2|DRUG: Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sinecort Pilot Efficacy Study
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DEVICE: Sinecort cream|DRUG: Hydrocortison cream|OTHER: Untreated skin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cognitive Behavioural Therapy as an Effective Treatment for Social Anxiety, Perfectionism, and Rumination
Status: UNKNOWN
Conditions: Social Anxiety Disorder
Interventions: BEHAVIORAL: Cognitive Behavioural Therapy as an Effective Treatment for Social Anxiety, Perfectionism, and Rumination
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Does Autologous Fat Transplantation Improve Results and Reduce Complications in Breast Reconstruction With Implants?
Status: UNKNOWN
Conditions: Breast Neoplasms
Interventions: PROCEDURE: Autologous fat transplantation|PROCEDURE: Expander prosthesis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Amlodipine Versus Valsartan for Improvement of Diastolic Dysfunction Associated With Hypertension
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Amlodipine|DRUG: Valsartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cetuximab and Radiation Therapy for Surgically Resectable Esophageal and Gastroesophageal (GE) Junction Carcinomas
Status: COMPLETED
Conditions: Esophageal Cancer
Interventions: PROCEDURE: Radiation Therapy|PROCEDURE: Surgery|PROCEDURE: Tissue Sample
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Vandetanib on Cellular Markers in Invasive Breast Cancer
Status: TERMINATED
Conditions: Invasive Breast Cancer
Interventions: DRUG: Vandetanib|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Visual Attention Span Mobilisation for Dyslexia
Status: COMPLETED
Conditions: Dyslexia|Visual Attention Span Deficit
Interventions: DEVICE: MAEVAD|DEVICE: DeCaLigne
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Biomarkers in Patients Undergoing Transrectal Ultrasound Prostate Biopsy
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: GENETIC: proteomic profiling|OTHER: immunological diagnostic method|OTHER: laboratory biomarker analysis|OTHER: mass spectrometry|PROCEDURE: biopsy|PROCEDURE: ultrasound imaging
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Trial of SHR-A1811versus Pyrotinib in Combination With Capecitabine in HER2-Positive, Unresectable and/or Metastatic Breast Cancer Subjects Previously Treated With Trastuzumab and Taxane
Status: RECRUITING
Conditions: HER2-Positive, Unresectable and/or Metastatic Breast Cancer Subjects Previously Treated With Trastuzumab and Taxane
Interventions: DRUG: SHR-A1811|DRUG: Pyrotinib in combination with Capecitabine.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of a Resilience Model-Based Care Plan in Newly Diagnosed Colorectal Cancer Patients
Status: UNKNOWN
Conditions: Colon Cancer
Interventions: BEHAVIORAL: Resilience model-based total care plan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Influence of Physical Exercise as Adjuvant Treatment in Patients With Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer Disease
Interventions: OTHER: Supervised Physical Activity (AMRAP -As Many Repetitions As Possible): Phase 2|OTHER: Supervised Physical Activity: Phase 1
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Longitudinal Evaluation of Women Undergoing Pelvic Surgery for the Treatment of Gynecologic Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Cervical Carcinoma|Endometrial Carcinoma|Malignant Female Reproductive System Neoplasm|Vaginal Carcinoma|Vulvar Carcinoma
Interventions: OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Studies of the Ocular Complications of AIDS (SOCA)--Monoclonal Antibody CMV Retinitis Trial (MACRT)
Status: COMPLETED
Conditions: HIV Infections|Cytomegalovirus Retinitis
Interventions: DRUG: MSL-109|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Impact of CES1 Genotype on Metabolism of Methylphenidate
Status: COMPLETED
Conditions: Carboxylesterase 1 (CES1) Genotype|CES1 Activity
Interventions: DRUG: Methylphenidate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Renal Sympathetic Denervation on the Cardiac and Renal Functions in Patients With Drug-resistant Hypertension Through MRI Evaluation
Status: UNKNOWN
Conditions: Uncontrolled Hypertension
Interventions: PROCEDURE: Renal Denervation (EnligHTN™) Renal artery ablation with the EnligHTN™ Renal Denervation System.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose Finding Study for QAW039 in Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: QAW039|DRUG: Montelukast|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vaginal Testosterone Cream vs ESTRING for Vaginal Dryness or Decreased Libido in Early Stage Breast Cancer Patients
Status: COMPLETED
Conditions: Sexual Dysfunction, Physiological
Interventions: DRUG: Testosterone Cream|DRUG: Estring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Multicenter Study to Evaluate the Cholesterol Lowering Effects of Two Marketed Products in Patients With Type 2 Diabetes Mellitus and Hypercholesterolemia (MK-0653A-077)
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus|Hypercholesterolemia
Interventions: DRUG: MK0653A, ezetimibe (+) simvastatin|DRUG: Duration of Treatment: 4 wk placebo run in then 6 wk active|DRUG: Comparator: atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study To Assess the Safety and Effects of OnabotulinumtoxinA (BOTOX) Intramuscular Injection in Adult Participants With Platysma Prominence
Status: COMPLETED
Conditions: Platysma Prominence
Interventions: DRUG: OnabotulinumtoxinA|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety Study of Recombinant Two-Component COVID-19 Vaccine (CHO Cell)(ReCOV)
Status: COMPLETED
Conditions: COVID-19
Interventions: BIOLOGICAL: Recombinant two-component COVID-19 vaccine (CHO cell)|BIOLOGICAL: COVID-19 Vaccine (Vero Cell), Inactivated
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Cabozantinib S-Malate in Treating Younger Patients With Recurrent or Refractory Solid Tumors
Status: COMPLETED
Conditions: Recurrent Malignant Solid Neoplasm|Recurrent Melanoma|Recurrent Primary Central Nervous System Neoplasm|Recurrent Thyroid Gland Carcinoma|Refractory Malignant Solid Neoplasm|Refractory Primary Central Nervous System Neoplasm|Thyroid Gland Medullary Carcinoma
Interventions: DRUG: Cabozantinib S-malate|OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacological Study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cognitive/Physical Computer-Game Blended Training of Elderly: Neuroscientific LLM Studies
Status: COMPLETED
Conditions: Mild Cognitive Impairment, So Stated|Mild Dementia|Healthy
Interventions: OTHER: LLM|OTHER: FFA|OTHER: Brain Fitness|OTHER: VideoGrade
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Natural History and Management of Von Hippel-Lindau (VHL) Associated Pancreatic Neuroendocrine Tumors
Status: RECRUITING
Conditions: VHL Pancreatic Neuroendocrine Tumors|Von Hippel-Lindau Disease|Neuroendocrine Tumors
Interventions: DRUG: 68-Gallium DOTATATE
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Implementing a Skills-Based Caregiver Training Program (Caregivers FIRST): Function QUERI 2.0
Status: ACTIVE_NOT_RECRUITING
Conditions: Cognitive Function|Functional Status
Interventions: OTHER: Implementation Strategy: Foundational REP|OTHER: Implementation Strategy: Enhanced REP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Safety Study of Etripamil Nasal Spray for Patients With Paroxysmal Supraventricular Tachycardia. NODE-303
Status: COMPLETED
Conditions: Paroxysmal Supraventricular Tachycardia
Interventions: DRUG: Etripamil NS
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Docetaxel With or Without Bintrafusp Alfa for the Treatment of Advanced Non-small Cell Lung Cancer
Status: TERMINATED
Conditions: Advanced Lung Non-Small Cell Carcinoma|Stage III Lung Cancer AJCC v8|Stage IIIA Lung Cancer AJCC v8|Stage IIIB Lung Cancer AJCC v8|Stage IIIC Lung Cancer AJCC v8|Stage IV Lung Cancer AJCC v8|Stage IVA Lung Cancer AJCC v8|Stage IVB Lung Cancer AJCC v8
Interventions: DRUG: Bintrafusp Alfa|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of Bibliotherapy on Emotional Distress, Coping Strategies and Resilience of Adolescents With Cancer
Status: COMPLETED
Conditions: Emotional Distress|Pediatric Cancer
Interventions: OTHER: interactive bibliotherapy|OTHER: reading bibliotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Efficacy of Sofosbuvir/Velpatasvir/Voxilaprevir in Adults With Chronic HCV Infection Who Have Previously Received Treatment With Direct-Acting Antiviral Therapy
Status: COMPLETED
Conditions: Hepatitis C
Interventions: DRUG: SOF/VEL/VOX|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Mindfulness-Oriented Recovery Enhancement For Chronic Pain and Prescription Opioid Misuse in Primary Care
Status: COMPLETED
Conditions: Chronic Pain|Opioid Use Disorders
Interventions: BEHAVIORAL: Mindfulness-Oriented Recovery Enhancement|BEHAVIORAL: Support Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intensity-Modulated External Beam Radiation Therapy in Treating Patients With Prostate Cancer
Status: COMPLETED
Conditions: Adenocarcinoma of the Prostate|Stage I Prostate Cancer|Stage II Prostate Cancer|Stage III Prostate Cancer|Stage IV Prostate Cancer
Interventions: RADIATION: intensity modulated external beam radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study On Bioavailability And Pharmacokinetics Of Various Doses Of Testosterone Administered With And Without Dutasteride
Status: COMPLETED
Conditions: Hypogonadism|Hypogonadism, Male
Interventions: DRUG: Nanomilled testosterone|DRUG: commercially available dutasteride|DRUG: Nanomilled dutasteride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Effects of Brilacidin Oral Rinse on Radiation-induced Oral Mucositis in Patients With Head and Neck Cancer
Status: COMPLETED
Conditions: Head and Neck Neoplasms|Mucositis
Interventions: DRUG: Brilacidin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Cabazitaxel Combined With Prednisone and Prophylaxis of Neutropenia Complications in the Treatment of Patients With Metastatic Castration-resistant Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: CABAZITAXEL (XRP6258)|DRUG: Prednisone|DRUG: Ciprofloxacin|DRUG: G-CSF (Granulocyte colony-stimulating factor)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single Injection Adductor Canal Block vs Catheter for Total Knee Arthroplasty
Status: COMPLETED
Conditions: Total Knee Arthroplasty
Interventions: DRUG: Adductor canal block|DRUG: Adductor canal block with dexamethasone|DRUG: Adductor canal catheter|DRUG: Bupivacaine|DRUG: Fentanyl|DRUG: Ropivacaine 0.5% Injectable Solution|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fluoxetine in Pediatric Body Dysmorphic Disorder
Status: COMPLETED
Conditions: Body Dysmorphic Disorder
Interventions: DRUG: Fluoxetine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Assessment of Preoperative Psychological Intervention on Stress in Women With Gynecological Malignancies
Status: UNKNOWN
Conditions: Cancer of Cervix|Ovarian Cancer|Cancer of Endometrium
Interventions: BEHAVIORAL: Cognitive intervention|OTHER: Control group|OTHER: psycho-physiological intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Body Weight Supported Treadmill Training as Physical Therapy Treatment to Spinal Cord Injury Patients
Status: COMPLETED
Conditions: Spinal Cord Injury/Damage
Interventions: PROCEDURE: BWSTT (3 days a week for maximum of 20 minutes session)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cetuximab Plus Capecitabine as Maintenance Treatment in RAS and BRAF wt Metastatic Colorectal Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Colorectal Cancer
Interventions: DRUG: Cetuximab, Capecitabine|DRUG: Cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cryoenergy Or Radiofrequency for Pulmonary Vein Isolation
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DEVICE: Pulmonary vein cryoablation|DEVICE: Pulmonary vein radiofrequency ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sunitinib Malate in Treating Patients With Unresectable or Metastatic Kidney Cancer or Other Advanced Solid Tumors
Status: COMPLETED
Conditions: Adult Solid Neoplasm|Clear Cell Renal Cell Carcinoma|Recurrent Renal Cell Carcinoma|Stage III Renal Cell Cancer|Stage IV Renal Cell Cancer
Interventions: OTHER: Computed Tomography|OTHER: Fluorothymidine F-18|OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacological Study|OTHER: Positron Emission Tomography|DRUG: Sunitinib Malate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Safety and Effectiveness of a Two-Drug Combination in the Treatment of Patients With Hepatitis C Plus Advanced HIV Infections
Status: COMPLETED
Conditions: HIV Infections|Hepatitis C
Interventions: DRUG: Interferon alfa-2b|DRUG: Zidovudine|DRUG: Zalcitabine|DRUG: Didanosine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Pharmacokinetics of Single and Multiple Doses of Apremilast in Healthy Adult Male Korean Subjects
Status: COMPLETED
Conditions: Pharmacokinetics
Interventions: DRUG: Apremilast|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BP31510 (Ubidecarenone,USP) Nanosuspension for Intravenous Injection to Patients With Solid Tumors
Status: COMPLETED
Conditions: Metastatic Cancer|Cancer|Solid Tumor
Interventions: DRUG: BP31510 monotherapy|DRUG: BP31510 in combination with chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Mirtazapine in Cancer-related Poly-symptomatology
Status: TERMINATED
Conditions: Cancer|Neoplasms|Neoplasm Metastasis
Interventions: DRUG: Mirtazapine|DRUG: Escitalopram
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimal Coronary Sinus Lead Implantation Using Intracardiac Impedography and Magnetic Resonance Imaging
Status: COMPLETED
Conditions: Heart Failure, Systolic|Left Bundle Branch Block
Interventions: PROCEDURE: Cardiac Resynchronization Therapy (CRT) implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Postoperative Analgesia in Children After Propofol Anesthesia
Status: UNKNOWN
Conditions: Postoperative Pain
Interventions: DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Stroke Treatment Associate to Rehabilitation Therapy and Transcranial DC Stimulation
Status: UNKNOWN
Conditions: Stroke|Cerebrovascular Disorders|Cerebral Infarction
Interventions: DEVICE: Transcranial direct current stimulation|BEHAVIORAL: Constraint-Induced Movement Therapy|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Effects of Gong's Mobilization With Gradually Graded Exercise Therapy
Status: COMPLETED
Conditions: Chronic Pain|Neck Pain|Shoulder Syndrome
Interventions: OTHER: Gong's Mobilization|OTHER: Gradually Graded Exercise Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Modified Dakin's Solution in Reducing Radiation-Induced Dermatitis in Patients With Head and Neck Cancer Undergoing Radiation Therapy
Status: COMPLETED
Conditions: Head and Neck Carcinoma|Radiation-Induced Dermatitis
Interventions: DRUG: Dakin's solution|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Immediate and Long-term Induction of Incretin Release by Artificial Sweeteners 1
Status: COMPLETED
Conditions: Pre-diabetes|Diabetes
Interventions: OTHER: oral stimulation glucose|OTHER: oral stimulation saccharin|OTHER: oral stimulation aspartame|OTHER: oral stimulation sucralose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of an Investigational Medication for the Treatment of Secondary Hyperparathyroidism in Dialysis Patients
Status: COMPLETED
Conditions: Secondary Hyperparathyroidism|End Stage Renal Disease
Interventions: DRUG: AMG 073|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of STSA-1002 in Healthy Subjects
Status: COMPLETED
Conditions: Healthy Subject
Interventions: DRUG: STSA-1002 Injection|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of NKT2152, a HIF2α Inhibitor, in Patients With Advanced Clear Cell Renal Cell Carcinoma
Status: RECRUITING
Conditions: ccRCC|Clear Cell Renal Cell Carcinoma|Kidney Cancer|Kidney Neoplasms|Renal Cancer|Renal Neoplasms|Recurrent Renal Cell Carcinoma|Metastatic Renal Cell Carcinoma|Refractory Renal Cell Carcinoma|Advanced Renal Cell Carcinoma|Hypoxia|Renal Cell Carcinoma|Hypoxia Inducible Factor (HIF)|HIF2α Inhibitor|Hypoxia Inducible Factor 2 Alpha (HIF-2 Alpha)|Hypoxia Inducible Factor 2α (HIF-2α)|Clear Cell
Interventions: DRUG: Oral NKT2152
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Autologous Fat Enhanced w/ Regenerative Cells Transplanted to Reconstruct Breast Deformities After Lumpectomy
Status: COMPLETED
Conditions: Breast Neoplasms|Carcinoma, Ductal, Breast|Mammaplasty|Mastectomy, Segmental, Lumpectomy, Breast Reconstruction,
Interventions: PROCEDURE: ADRC-Enhanced Autologous Fat Transplant
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Physiological Strain Induced by a BC Membrane Protective Garment Under Exercise-heat Stress Compared to a Protective Coverall
Status: UNKNOWN
Conditions: Physiological Stress
Interventions: OTHER: exercise under hot and humid conditions protocol|DEVICE: BC membrane protective garment|DEVICE: NBC mask
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: The Effect of Remote Ischemic Preconditioning in Living Donor Hepatectomy
Status: COMPLETED
Conditions: Tissue Donors|Liver Transplantation|Ischemia Reperfusion Injury
Interventions: PROCEDURE: remote ischemic preconditioning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Safety Study of a Vaccine (DENV-1 PIV) to Prevent Dengue Disease
Status: COMPLETED
Conditions: Dengue Fever
Interventions: BIOLOGICAL: DENV-1 PIV, 2.5 µg|BIOLOGICAL: DENV-1 PIV, 5 µg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy of Combining Intranasal Insulin & Acute Exercise
Status: COMPLETED
Conditions: Insulin|Exercise
Interventions: DRUG: Placebo into the intranasal mucosa|DRUG: 20 IU NovoLog Insulin aspart into the intranasal mucosa|DRUG: 40 IU NovoLog Insulin aspart into the intranasal mucosa|DRUG: 60 IU NovoLog Insulin aspart into the intranasal mucosa|DRUG: 80 IU NovoLog Insulin aspart into the intranasal mucosa|DRUG: 100 IU NovoLog Insulin aspart into the intranasal mucosa|DRUG: 120 IU NovoLog Insulin aspart into the intranasal mucosa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study to Evaluate the Efficacy and Safety of Hemocoagulase Injection
Status: UNKNOWN
Conditions: Hemoptysis
Interventions: DRUG: Snake venom thrombin (Treatment)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Down Syndrome and Effects of Foot Muscle Exercise
Status: COMPLETED
Conditions: Pes Planus Down Syndrome Patients
Interventions: OTHER: Foot Muscle Exercise Protocol|COMBINATION_PRODUCT: Arch Support Insole and One Leg Balance Activities
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Laparoscopic Versus Open Gastrectomy for Advanced Gastric Cancer:A Prospective Randomized Trial
Status: UNKNOWN
Conditions: Stomach Neoplasm|Laparoscopy|Gastrectomy|Complications
Interventions: PROCEDURE: Laparoscopy-assisted gastrectomy|PROCEDURE: Open gastrectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 12 Weeks Treatment With 3 Different Doses of BI 10773 in Type 2 Diabetic Patients
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: BI 10773|DRUG: placebo|DRUG: metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: Effects of Three Different Mouth Rinses on Dental Plaque in Children
Status: COMPLETED
Conditions: Gingival Diseases
Interventions: DRUG: sodium fluoride solution|DRUG: guava leaves aqueous extract|DRUG: pomegranate peel aqueous extrac|OTHER: Distilled water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Two Different Dosages of Irinotecan Combined With Cisplatin Scheme in Extensive Disease-Small Cell Lung Cancer
Status: UNKNOWN
Conditions: Small Cell Lung Carcinoma
Interventions: DRUG: Irinotecan|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Biventricular Tachycardias Outcome Trial
Status: COMPLETED
Conditions: Biventricular Tachycardias
Interventions: DEVICE: Ovatio CRT 6750|DEVICE: Ovatio CRT 6750
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: At Home Placebo-controlled 8-week GOS Intervention on Emotion Behaviour and Cognition in Children (Age 6-14 Years).
Status: COMPLETED
Conditions: Emotional Regulation
Interventions: DIETARY_SUPPLEMENT: Galacto-oligosaccharide|DIETARY_SUPPLEMENT: Maltodextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Baska ® Mask Versus Endotracheal Tube in Laparoscopic Cholecystectomy
Status: COMPLETED
Conditions: Laparoscopic Surgery
Interventions: DEVICE: BASKA mask|DEVICE: Endotracheal intubation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: CO2 as a Stress Agent for Perfusion Imaging
Status: TERMINATED
Conditions: Coronary Artery Disease
Interventions: DEVICE: Delivery of precise levels of carbon dioxide with the RA-MR™ Virtual Sequential Gas Delivery System.|DEVICE: Delivery of rubidium radioisotope (Rb-82) using the automated pump/elution system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Blood Stem Cell Transplantation for the Treatment of Older Patients With Acute Myelogenous Leukemia
Status: COMPLETED
Conditions: Acute Myelogenous Leukemia
Interventions: DRUG: Fludarabine|DRUG: Busulfan|RADIATION: Total Body Irradiation|PROCEDURE: Stem Cell Transplant
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antiviral Therapy Plus Either Peripheral Stem Cell or Umbilical Cord Blood Transplantation in Treating Patients Who Are HIV Positive and Have Hematologic Cancer
Status: WITHDRAWN
Conditions: Leukemia|Lymphoma
Interventions: BIOLOGICAL: anti-thymocyte globulin|DRUG: melphalan|PROCEDURE: antiviral therapy|PROCEDURE: bone marrow ablation with stem cell support|PROCEDURE: peripheral blood stem cell transplantation|PROCEDURE: umbilical cord blood transplantation|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: The Treatment of Coronary De-novo Lesions With the Elutax Paclitaxel-eluting Balloon Alone, a Pilot Study
Status: TERMINATED
Conditions: Stable Angina|Coronary Stenosis
Interventions: DEVICE: drug eluting balloon|DEVICE: drug eluting stent
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Non-interventional Multi-center Study on Patients Under Routine Treatment of Pulmonary Arterial Hypertension (PAH) With Inhaled Iloprost Using I-Neb as a Device for Inhalation
Status: COMPLETED
Conditions: Pulmonary Hypertension
Interventions: DRUG: Iloprost (Ventavis, BAYQ 6256)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety of Two Different Brolucizumab 6 mg Dosing Regimens in Neovascular Age-related Macular Degeneration
Status: COMPLETED
Conditions: Age-related Macular Degeneration
Interventions: BIOLOGICAL: Brolucizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Tibial and Femoral Tunnel Position After Arthroscopic Reconstruction of the Anterior Cruciate Ligament
Status: COMPLETED
Conditions: Anterior Cruciate Ligament Rupture
Interventions: PROCEDURE: Anterior cruciate ligament reconstruction
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Mobile Intervention to Improve Adherence of Oral Anti-cancer Medications Among Acute Myeloid Leukemia Patients, the txt4AML Study
Status: WITHDRAWN
Conditions: Acute Myeloid Leukemia
Interventions: OTHER: Text Message-Based Navigation Intervention|OTHER: Behavioral, Psychological or Informational Intervention|OTHER: Survey Administration|OTHER: Quality-of-Life Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study of the Safety and Tolerability of GWP42006 in Healthy Subjects
Status: COMPLETED
Conditions: Epilepsy
Interventions: DRUG: Placebo|DRUG: GWP42006
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: pBFS Guided rTMS Over Cognitive Control Network for ASD
Status: NOT_YET_RECRUITING
Conditions: Autism Spectrum Disorder
Interventions: DEVICE: active iTBS treatment|DEVICE: sham iTBS treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Progesterone Serum Levels in Subfertile Female Patients Undergoing in Vitro Fertilisation (IVF)
Status: COMPLETED
Conditions: Infertility
Interventions: DRUG: Menotrophin|DRUG: Follitrophin alpha|DRUG: Cetrorelix|DRUG: Choriongonadotropin|DRUG: Progesterone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of TEAS on PONV After Spinal Surgery
Status: RECRUITING
Conditions: PONV
Interventions: DEVICE: TEAS via ES-130|OTHER: No TEAS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of ES014 (Anti-CD39/TGF-β Bispecific Antibody) in Patients With Locally Advanced or Metastatic Solid Tumors
Status: WITHDRAWN
Conditions: Advanced Solid Tumor
Interventions: DRUG: ES014|DRUG: ES014
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating PF-03084014 In Patients With Advanced Breast Cancer With Or Without Notch Alterations
Status: TERMINATED
Conditions: Triple Negative Breast Neoplasms
Interventions: DRUG: PF-03084014|DRUG: PF-03084014|DRUG: PF-03084014
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Naltrexone as a Treatment for Self-injurious Behavior
Status: WITHDRAWN
Conditions: Self-injurious Behavior|Self Mutilation
Interventions: DRUG: Naltrexone|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Investigation Of The Absorption And Pharmacokinetics Of Multiple Doses Of A Controlled Release Pregabalin Tablet As Compared To Multiple Doses Of The Immediate Release Pregabalin Capsule
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Pregabalin controlled release, 82.5 mg|DRUG: Pregabalin immediate release, 25 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Infraclavicular Block Properties in Diabetic Patients
Status: COMPLETED
Conditions: Diabetes Mellitus|Nerve Block Duration|Pain, Postoperative
Interventions: DRUG: Infraclavicular Brachial Plexus Blocks|DRUG: Infraclavicular Brachial Plexus Blocks
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety of Transplantation of CRISPR CCR5 Modified CD34+ Cells in HIV-infected Subjects With Hematological Malignances
Status: UNKNOWN
Conditions: HIV-1-infection
Interventions: GENETIC: CCR5 gene modification
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Effect of Tocilizumab + Methotrexate on Prevention of Structural Joint Damage in Patients With Moderate to Severe Active Rheumatoid Arthritis (RA)
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: tocilizumab [RoActemra/Actemra]|DRUG: Placebo|DRUG: Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Chlorhexidine Gluconate-gel Dressing for Exit Site Infection in Peritoneal Dialysis
Status: COMPLETED
Conditions: Peritoneal Dialysis Catheter Exit Site Infection|End Stage Renal Disease on Dialysis|Dialysis; Complications
Interventions: OTHER: Chlorhexidine Gluconate-gel (CHG) Dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Contrast-Enhanced Ultrasound Imaging for Diagnosing Recurrent Renal Cell Carcinoma (RCC) Post Ablation
Status: RECRUITING
Conditions: Recurrent Renal Cell Carcinoma|Renal Cell Carcinoma
Interventions: DRUG: Sulfur Hexafluoride Lipid Microspheres|PROCEDURE: Contrast-Enhanced Ultrasound|PROCEDURE: Computed Tomography|PROCEDURE: Magnetic Resonance Imaging|OTHER: Electronic Health Record Review
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Stereotactic Body Radiation Therapy in Treating Patients With Stage I or Stage II Non-Small Cell Lung Cancer
Status: WITHDRAWN
Conditions: Lung Cancer
Interventions: PROCEDURE: computed tomography|PROCEDURE: positron emission tomography|RADIATION: stereotactic body radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A New Modified-release Tablet Formulation of Prednisone (Lodotra®) in Patients With Nocturnal Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Lodotra|DRUG: Cortancyl
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Driving Evaluation and Fitness for Persons With Cognitive Impairments
Status: COMPLETED
Conditions: Mild Cognitive Impairment|Dementia, Mild|Driving Impaired|Drive
Interventions: OTHER: driving evaluation and practice
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: An Economic Study of HSK21542 Injection for Prevention of Postoperative Nausea and Vomiting
Status: RECRUITING
Conditions: Nausea and Vomiting, Postoperative
Interventions: DRUG: HSK21542|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Fluorescein vs. iMRI in Resection of Malignant High Grade Glioma
Status: WITHDRAWN
Conditions: High Grade Malignant Neoplasm|Glioblastoma Multiforme|Anaplastic Astrocytoma
Interventions: OTHER: fluorescein|OTHER: intraoperative MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: High-Risk Neuroblastoma Study 2 of SIOP-Europa-Neuroblastoma (SIOPEN)
Status: RECRUITING
Conditions: High-Risk Neuroblastoma|Patient With Insufficient Response Chemoimmunotherapy
Interventions: DRUG: Vincristine|DRUG: Carboplatin|DRUG: Etoposide|DRUG: Vindesine|DRUG: Dacarbazine|DRUG: Ifosfamide|DRUG: Doxorubicin|DRUG: Busulfan|DRUG: Melphalan|DRUG: Thiotepa|RADIATION: Radiotherapy|DRUG: Dinutuximab Beta|DRUG: Cisplatin|DRUG: Temozolomide 100 MG|DRUG: Irinotecan|DRUG: Cyclophosphamid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Progressive Active Exercise After Surgical Rotator Cuff Repair
Status: COMPLETED
Conditions: Rotator Cuff Tear
Interventions: BEHAVIORAL: Progressive early passive and active movement|BEHAVIORAL: Limited early passive movement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Augmented Reality-assisted Localization of Solitary Pulmonary Nodules for Precise Sublobar Lung Resection
Status: UNKNOWN
Conditions: SPN|Lung Cancer
Interventions: DEVICE: Augmented Reality-assisted localization of solitary pulmonary nodule
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Autologous Stem Cells for the Treatment of No Option Critical Limb Ischemia
Status: COMPLETED
Conditions: Critical Limb Ischemia
Interventions: DRUG: 20 million hMSCs|DRUG: 40 million hMSCs|DRUG: 80 million hMSCs
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness Study of the Drug Tranexamic Acid to Reduce Post-surgery Blood Loss in Spinal Surgery
Status: COMPLETED
Conditions: Lumbar Spinal Stenosis|Thoracic Spinal Stenosis
Interventions: DRUG: Tranexamic Acid|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Evaluation of a Nasal Pillows Mask for the Treatment of Obstructive Sleep Apnea (OSA) in NZ
Status: COMPLETED
Conditions: Obstructive Sleep Apnea
Interventions: DEVICE: New Nasal Pillows Mask
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tipifarnib and Bortezomib in Treating Patients With Relapsed Multiple Myeloma
Status: TERMINATED
Conditions: Refractory Multiple Myeloma|Stage II Multiple Myeloma|Stage III Multiple Myeloma
Interventions: DRUG: bortezomib|DRUG: tipifarnib|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Systemic Exposure to Ciclesonide Nasal Spray, Ciclesonide HFA Nasal Aerosol and Orally Inhaled Ciclesonide (BY9010/M1-422)
Status: COMPLETED
Conditions: Allergic Rhinitis
Interventions: DRUG: Ciclesonide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment Outcomes With Full Arch Rehabilitations Retained by Immediate or Conventionally Loaded Implants
Status: COMPLETED
Conditions: Edentulous Jaw|Missing Teeth
Interventions: PROCEDURE: Implant supported dentures
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Local Control, Quality of Life and Toxicities in Adults With Benign or Indolent Brain Tumors Undergoing Proton Radiation Therapy
Status: RECRUITING
Conditions: Brain Tumor
Interventions: RADIATION: Proton Radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lung-MAP: Durvalumab as Second-Line Therapy in Treating Patients With Recurrent Stage IV Squamous Cell Lung Cancer and No Matching Biomarkers
Status: COMPLETED
Conditions: Recurrent Squamous Cell Lung Carcinoma|Stage IV Squamous Cell Lung Carcinoma AJCC v7
Interventions: DRUG: Docetaxel|BIOLOGICAL: Durvalumab|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Predictors of Pulmonary Hypertension in Patients With Hypersensitivity Pneumonitis
Status: COMPLETED
Conditions: Pulmonary Hypertension|Hypersensitivity Pneumonitis
Interventions: PROCEDURE: Right heart catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: CD62L Depleted Donor Lymphocyte Infusion With T Cell Depleted Haploidentical Hematopoietic Stem Cell Transplantation
Status: RECRUITING
Conditions: Hematopoietic Organs; Disorder
Interventions: BIOLOGICAL: CD62L depleted donor lymphocyte infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT