pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Maintenance Dose Study of GEN-003 in Subjects With Genital Herpes Infection
Status: TERMINATED
Conditions: Genital Herpes|HSV-2 Infection
Interventions: BIOLOGICAL: GEN-003|BIOLOGICAL: Matrix-M2|OTHER: 0.9% normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Antibiotic Prophylaxis in Transurethral Prostate Resection (TURP) and Transurethral Bladder Tumour Resection (TURB)
Status: COMPLETED
Conditions: Urosepsis|Bladder Cancer|Prostate Hyperplasia|Antibiotic Resistant Strain|Antibiotic Resistant Infection|Antibiotic-associated Diarrhea|Antibiotic Toxicity
Interventions: DRUG: Levofloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Artemisinin With Risperidone for First-Episode and Drug-Naive Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Artemisinin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study for Fluticasone Propionate 100 mcg/Salmeterol Xinafoate 50 mcg Inhalation Powder in Healthy Volunteers
Status: ACTIVE_NOT_RECRUITING
Conditions: Bioequivalence
Interventions: DRUG: Fluticasone propionate 1000 mcg and salmeterol xinafoate 50 mcg/Respirent Pharmaceuticals|DRUG: ADVAIR DISKUS 100/50
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Pazopanib Plus Lapatinib Compared To Lapatinib Alone In Subjects With Inflammatory Breast Cancer
Status: COMPLETED
Conditions: Neoplasms, Breast
Interventions: DRUG: lapatinib|DRUG: Pazopanib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study to Assess the Amnesic Properties of Propofol in Pediatric Patients
Status: COMPLETED
Conditions: Pediatric Pateints|Amnesic Properties of Propofol
Interventions: OTHER: memory test|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Dasatinib for Immune Modulation After Donor Stem Cell Transplant for Hematologic Malignancies
Status: TERMINATED
Conditions: Non-Hodgkin's Lymphoma|Hodgkin's Lymphoma|Myeloid Leukemia|Multiple Myeloma|Myelodysplastic Syndrome|Lymphoid Leukemia
Interventions: DRUG: Dasatinib|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of MNC-168 Enteric-coated Capsule in the Treatment of Advanced Intestinal Solid Tumor
Status: UNKNOWN
Conditions: Advanced Malignant Solid Tumors
Interventions: DRUG: Treatment of MNC-168 enteric-coated capsules as a single oral drug
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Expanded Access Study Of BEXXAR® For Low Grade And Transformed Low-Grade Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Lymphoma, Non-Hodgkin
Interventions: BIOLOGICAL: Iodine I 131 Tositumomab Therapeutic Regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose:
Clinical trial: The Effect of a Nutritional Supplement in Individuals With Type 2 Diabetes Mellitus: a Pilot Study
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Insulin Resistance
Interventions: DIETARY_SUPPLEMENT: Zinc supplements|DIETARY_SUPPLEMENT: Omega 3 supplements|DIETARY_SUPPLEMENT: Placebo supplements
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of Simethicone In Improving Visibility During Colonoscopy
Status: COMPLETED
Conditions: Colonoscopy
Interventions: DRUG: Simethicone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Teachers Leading the Front Lines - Adolescent
Status: NOT_YET_RECRUITING
Conditions: Adolescent Behavior|Adolescent - Emotional Problem|Mental Health Issue|Psychosocial Functioning|Depression|Anxiety
Interventions: BEHAVIORAL: Tealeaf-Mansik Swasta (Tealeaf) as adapted for Adolescents|BEHAVIORAL: Enhanced Usual Care (EUC)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Safety and Efficacy of Xyrem Oral Solution (Sodium Oxybate) Compared With Placebo in Narcoleptic Patients
Status: COMPLETED
Conditions: Narcolepsy
Interventions: DRUG: sodium oxybate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Safety, and Pharmacokinetics of QAW039
Status: COMPLETED
Conditions: Persistent Asthma
Interventions: DRUG: QAW039 capsules once daily for 28 days|DRUG: Placebo to QAW039 capsules once daily for 28 days|DRUG: Fluticasone propionate inhaler twice daily for 28 days
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Amniotic Fluid Lactate in Perterm Premature Rupture of Membranes
Status: UNKNOWN
Conditions: Rupture of Membranes; Premature
Interventions: DIAGNOSTIC_TEST: amniotic fluid lactate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Cross-sectional Study to Measure Cough in Severe Asthma
Status: COMPLETED
Conditions: Asthma|Cough
Interventions: DRUG: Citric acid|DEVICE: Leicester Cough monitor|OTHER: fractional exhaled nitric oxide testing (FeNO)|OTHER: Patient reported outcome measures
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Impact of Systematic Nursing Guidance on the Psychological Effects of Parents of Children With Cardiac Catheterization.
Status: UNKNOWN
Conditions: Educational Videos|Catheterization|Congenital Heart Disease in Children|Parental Uncertainty|Parental Anxiety
Interventions: OTHER: routine education plus digital video disk|OTHER: routine education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: OTHER
Clinical trial: TAES for FPVCs: a Pragmatic, Randomized Controlled Trial
Status: RECRUITING
Conditions: Premature Ventricular Complexes
Interventions: DEVICE: Transcutaneous Auricular Vagus Nerve Stimulation (TAVNS)|DEVICE: Sham Transcutaneous Auricular Vagus Nerve Stimulation (Sham-TAVNS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: the Safety and Efficacy of Intravitreal Injection of Tpdelansbsalbac in Malignant Effusions.
Status: RECRUITING
Conditions: Salmonella Bacteremia
Interventions: BIOLOGICAL: Tpdelansbsalbac
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Limosilactobacillus Reuteri as an Adjuvant in the Treatment of Peri-implant Mucositis
Status: COMPLETED
Conditions: Peri-implant Mucositis
Interventions: DIETARY_SUPPLEMENT: Limosilactobacillus reuteri Prodentis® (combining L. reuteri DSM 17938 and L. reuteri ATCC PTA 5289 strains)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rural Hospital-Level Care at Home for Acutely Ill Adults
Status: COMPLETED
Conditions: Infections|Heart Failure|Chronic Obstructive Pulmonary Disease|Asthma|Gout Flare|Chronic Kidney Diseases|Hypertensive Urgency|Atrial Fibrillation Rapid|Anticoagulation|Diabetes and Its Complications|End of Life/Desires Only Medical Management
Interventions: OTHER: Home Hospital care|OTHER: Traditional Hospital care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Respiratory Proprioceptive Neuromuscular Facilitation Technique in Chronic Pulmonary Obstructive Disease Patients.
Status: COMPLETED
Conditions: COPD
Interventions: OTHER: Conventional|OTHER: PNF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Effect of Retatrutide Compared With Placebo in Participants With Type 2 Diabetes and Moderate or Severe Renal Impairment, With Inadequate Glycemic Control on Basal Insulin, With or Without Metformin and/or SGLT2 Inhibitor (TRANSCEND-T2D-3)
Status: RECRUITING
Conditions: Type 2 Diabetes
Interventions: DRUG: Retatrutide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Is it Effective to Treat Patients With Blastocystis Hominis Infection?
Status: UNKNOWN
Conditions: Blastocystis Hominis Infections
Interventions: DRUG: Metronidazole|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of EcoActive on Intestinal Adherent Invasive E. Coli in Patients With Inactive Crohn's Disease
Status: RECRUITING
Conditions: Crohn Disease
Interventions: BIOLOGICAL: Placebo|BIOLOGICAL: Bacteriophage preparation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Functional Imaging in Prediction of Response to Abemaciclib for Advanced Hormone Receptor-Positive, HER2-Negative Breast Cancer
Status: RECRUITING
Conditions: Anatomic Stage III Breast Cancer AJCC v8|Anatomic Stage IV Breast Cancer AJCC v8|Locally Advanced Unresectable HER2-Negative Breast Carcinoma|Locally Advanced Unresectable Hormone Receptor-Positive Breast Carcinoma|Metastatic HER2-Negative Breast Carcinoma|Metastatic Hormone Receptor-Positive Breast Carcinoma
Interventions: DRUG: Abemaciclib|DRUG: Anastrozole|PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|PROCEDURE: Diagnostic Imaging|DRUG: Exemestane|OTHER: Fludeoxyglucose F-18|DRUG: Fluorine F 18 Fluoro Furanyl Norprogesterone|DRUG: Fulvestrant|BIOLOGICAL: Gonadotropin-releasing Hormone Analog|DRUG: Letrozole|PROCEDURE: Positron Emission Tomography|DRUG: Tamoxifen|DRUG: Therapeutic Estradiol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MRG-001 as an Immunoregulatory and Regenerative Therapy for COVID-19 Patients
Status: UNKNOWN
Conditions: COVID-19|ARDS, Human|Stem Cells|Regeneration
Interventions: DRUG: MRG-001|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Fluticasone Furoate/Vilanterol on EIA in Adolescents
Status: COMPLETED
Conditions: Asthma in Children
Interventions: DRUG: Fluticasone furoate (FF)/Vilanterol (VI)|DRUG: Salbutamol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I/II Trial of Lentiviral Gene Transfer for SCID-X1 With Low Dose Targeted Busulfan Conditioning
Status: ACTIVE_NOT_RECRUITING
Conditions: Severe Combined Immunodeficiency, X Linked|Gene Therapy
Interventions: BIOLOGICAL: autologous CD34+ cell transduced with G2SCID vector
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Eplivanserin 5mg/Day on Sleep Maintenance Insomnia
Status: COMPLETED
Conditions: Sleep Initiation and Maintenance Disorders|Insomnia
Interventions: DRUG: eplivanserin (SR46349)|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Understanding Trauma Nightmares Using In-Home Measurement
Status: RECRUITING
Conditions: Nightmares|Stress Disorders, Post-Traumatic|Actigraphy|Respiratory Sinus Arrhythmia|Veterans
Interventions: BEHAVIORAL: Exposure, Relaxation, and Rescripting Therapy|BEHAVIORAL: Sleep and Nightmare Management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics Of AJ201 In Patients
Status: COMPLETED
Conditions: Spinal and Bulbar Muscular Atrophy|Kennedy's Disease
Interventions: DRUG: AJ201|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pre-operative Epirubicin, Cisplatin, and Capecitabine in Patients With Newly Diagnosed Localised Oesophageal Adenocarcinoma
Status: COMPLETED
Conditions: Adenocarcinoma of Oesophagus
Interventions: DRUG: epirubicin, capecitabine, cisplatin|PROCEDURE: Surgical resection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Dose-ranging Study to Evaluate the Safety and Efficacy of UNR844 in Subjects With Presbyopia.
Status: TERMINATED
Conditions: Presbyopia
Interventions: DRUG: UNR844|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of STRO-001, an Anti-CD74 Antibody Drug Conjugate, in Patients With Advanced B-Cell Malignancies
Status: COMPLETED
Conditions: B-cell Lymphoma|Non Hodgkin Lymphoma|Multiple Myeloma|Follicular Lymphoma|Mantle Cell Lymphoma|Diffuse Large B Cell Lymphoma|Indolent Lymphoma|B Cells--Tumors
Interventions: DRUG: STRO-001
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neurophysiological Correlates of Cognitive Tasks in Healthy Volunteers -WP3 P003
Status: UNKNOWN
Conditions: Alzheimer Disease|ELECTROENCEPHALOGRAPHIC VARIANT PATTERN 1 (Disorder)
Interventions: OTHER: Rapid Visual Information Processing (RVIP) test
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: An Open-label, Bioequivalence Study to Evaluate LEV Administered as a 45-min Intravenous Infusion and Same Dosage LEV Oral Tablet in Chinese
Status: COMPLETED
Conditions: Human Volunteers
Interventions: DRUG: Levetiracetam|DRUG: Levetiracetam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose Effects of SCF on Calcium Metabolism and GI Microflora in Adolescents
Status: COMPLETED
Conditions: Osteoporosis
Interventions: DIETARY_SUPPLEMENT: 0 grams SCF|DIETARY_SUPPLEMENT: 10 grams SCF|DIETARY_SUPPLEMENT: 20 grams SCF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Expansion to Interdisciplinary HIV Prevention in Women
Status: COMPLETED
Conditions: HIV|AIDS|Fetal Alcohol Syndrome|Alcohol Related Neurodevelopmental Disorder
Interventions: BEHAVIORAL: Opt-in or Opt-out testing|BEHAVIORAL: Focus Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Effect of Advance Care Planning to Improve Patient-centered Care of Nursing Home Residents
Status: COMPLETED
Conditions: Advance Care Planning|Nursing Homes
Interventions: OTHER: Implementation of a complex regional Advance Care Planning program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Dermatologic Tacrolimus Ointment on Eyelids in the Treatment of Refractory Vernal Keratoconjunctivitis and Atopic Keratoconjunctivitis
Status: UNKNOWN
Conditions: Vernal Keratoconjunctivitis|Atopic Keratoconjunctivitis|Tacrolimus
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy of Lidocaine Gel Enema After Endoscopic Hemorrhoid Band Ligation for Relief of Post Procedural Pain
Status: COMPLETED
Conditions: Hemorrhoids
Interventions: DRUG: Lidocaine Hydrochloride 2% gel enema
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effects of the Combined Therapy of Acupuncture and Yoga Exercise on Weight Loss
Status: UNKNOWN
Conditions: Obesity
Interventions: DEVICE: Acupuncture|BEHAVIORAL: Yoga exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Acupressure and Sleep Quality of Nursing Students
Status: COMPLETED
Conditions: Poor Quality Sleep
Interventions: OTHER: Acupressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Neoadjuvant vs Adjuvant in Locally Advanced Recurrent NPC
Status: RECRUITING
Conditions: Recurrent Nasopharyngeal Carcinoma
Interventions: PROCEDURE: endoscopic surgery|DRUG: Neoadjuvant therapy,Toripalimab Injection and Gemcitabine based therapy|DRUG: Adjuvant therapy in experimental group,Toripalimab Injection and Gemcitabine based therapy|DRUG: Adjuvant therapy in control group,Toripalimab Injection and Gemcitabine based therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: HAI-Floxuridine, or SIRT, Combined With Gemox For Patients With Intra-Hepatic Cholangiocarcinoma Not Amenable to Resection (TOMCAT)
Status: RECRUITING
Conditions: Intrahepatic Cholangiocarcinoma|Chemotherapy Effect
Interventions: DRUG: Floxuridine|PROCEDURE: Selective Internal Radiation Therapy (SIRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Healthy Diet Rich in Potassium to Chronic Kidney Disease With Sodium Zirconium Cyclosilicate: A Feasibility Study
Status: COMPLETED
Conditions: Chronic Kidney Disease stage4|Chronic Kidney Disease Stage 5|Hyperkalemia
Interventions: COMBINATION_PRODUCT: sodium zirconium cyclosilicate and healthy diet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Enhanced CBTi for Older Adult Sleep and Cognition
Status: COMPLETED
Conditions: Insomnia|Alzheimers Disease Related Dementias
Interventions: COMBINATION_PRODUCT: CBTi with Application|BEHAVIORAL: CBTi|BEHAVIORAL: Sleep Hygiene Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Open Label Extension Study of Epratuzumab in Japanese Systemic Lupus Erythematosus (SLE) Subjects
Status: COMPLETED
Conditions: Systemic Lupus Erythematosus
Interventions: BIOLOGICAL: Epratuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preoperative Highflow Nasal Oxygen Application in Cesarean Under General Anesthesia and Its Effects on Newborn.
Status: COMPLETED
Conditions: Cesarean Delivery Affecting Newborn
Interventions: DEVICE: high flow nasal oxygen device (POİNT)|DEVICE: Face mask
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: A Study to Evaluate the Safety, Tolerability, Pharmacokinetics (PK) and Pharmacodynamics (PD) of Repeat Doses of GSK2330672 Administration in Subjects With Primary Biliary Cirrhosis (PBC) and Symptoms of Pruritus
Status: COMPLETED
Conditions: Cholestasis, Intrahepatic
Interventions: DRUG: GSK2330672|DRUG: Placebo|DRUG: Ursodeoxycholic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Exploring Efficacy of Intensive Rosuvastatin Treatment Peri-PCI in Chinese Patients With Non ST-segment Elevated Acute Coronary Syndrome(NSTE-ACS)
Status: UNKNOWN
Conditions: Non-ST-elevation Acute Coronary Syndromes
Interventions: DRUG: Rosuvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Impact of a Polyphenol-Rich Supplement on Epigenetic and Cellular Markers of Immune Age
Status: COMPLETED
Conditions: Immunity Disorders|Aging|Inflammation
Interventions: DIETARY_SUPPLEMENT: HTB Rejuvenate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Local Effects of Amino Acids and 3-hydroxybutyrate in the Bilaterally Perfused Human Leg
Status: UNKNOWN
Conditions: Critical Illness|Protein Metabolism|Pharmaconutrients
Interventions: DIETARY_SUPPLEMENT: Vamin (Fresenius Kabi)|DIETARY_SUPPLEMENT: 3hydroxybutyrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Using the Prevent-Teach-Reinforce Model to Reduce Problem Behaviors in Children With Autism Spectrum Disorders
Status: COMPLETED
Conditions: Child Development Disorders, Pervasive
Interventions: BEHAVIORAL: Prevent-Teach-Reinforce Model|OTHER: Individual Parent Training Session
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Extramembranous and Interosseous Technique of Tibialis Posterior Tendon Transfer
Status: TERMINATED
Conditions: Muscle Injury|Nerve Injury|Poliomyelitis|Leprosy|Cerebral Palsy
Interventions: PROCEDURE: Interosseous route of TPTT|PROCEDURE: Extra membranous route of TPTT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Concentration of Ampicillin / Sulbactam and Amoxicillin / Clavulanic Acid in the Blood During Renal Replacement Therapy in Longterm Renal Replacement Therapy Patients
Status: COMPLETED
Conditions: Infection During Hemodialysis
Interventions: DRUG: Administration of Amoxicillin / clavulanic acid|DRUG: Ampicillin / sulbactam|PROCEDURE: Blooddraws for pharmacokinetic profiling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of ICCAUT Strategy on Postoperative Urinary Dysfunction After Radical Rectal Cancer Surgery
Status: RECRUITING
Conditions: Urinary Dysfunction|Rectal Cancer|Urinary Catheterization|Urinary Retention Postoperative
Interventions: PROCEDURE: ICCAUT|PROCEDURE: Free drainage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Nutritional Supplementation in Preventing Malnutrition in Children With Infection
Status: COMPLETED
Conditions: Malnutrition|Malaria|Lower Respiratory Tract Infection|Diarrhoea
Interventions: DIETARY_SUPPLEMENT: Ready to Use Therapeutic Food (RUTF)|DIETARY_SUPPLEMENT: Micronutrient Powder (MNP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of High Dose Vitamin D on Cancer Biomarkers and Breast Cancer Tumors
Status: WITHDRAWN
Conditions: Breast Cancer|Invasive Breast Carcinoma|Ductal Carcinoma In-situ
Interventions: DRUG: Vitamin D3
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Sand Treatment on Osteoarthritis
Status: TERMINATED
Conditions: Osteo Arthritis Knee
Interventions: RADIATION: Natural gamma radiation from the monazite sands|RADIATION: Normal sands exposure patients
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Chemotherapy Plus Radiation Therapy in Treating Patients With Stage I, Stage II, or Stage III Non-small Cell Lung Cancer That Cannot Be Surgically Removed
Status: TERMINATED
Conditions: Lung Cancer
Interventions: DRUG: cisplatin|DRUG: gemcitabine hydrochloride|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: A Study on the Safety and Efficacy of the SCu300A IUB Compared to the TCu380 Copper IUD
Status: WITHDRAWN
Conditions: Reversible Prevention of Pregnancy
Interventions: DEVICE: SCu300A IUB|DEVICE: TCu380A IUD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: A Comparison Between Propofol-Remifentanil and Midazolam-Remifentanil Sedation in the Intensive Care Unit
Status: COMPLETED
Conditions: Sedation
Interventions: DRUG: Propofol infusion|DRUG: Midazolam infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Epigenetic Regulation of Colorectal Polyps and Cancer
Status: RECRUITING
Conditions: Colorectal Cancer|Colorectal Polyp|Colorectal Adenoma|Colorectal Neoplasms
Interventions: DIAGNOSTIC_TEST: Intestinal biopsies|DIAGNOSTIC_TEST: Blood sample
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study With AG-013736 Combined With Chemotherapy And Bevacizumab In Patients With Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Neoplasms
Interventions: DRUG: bevacizumab|DRUG: AG-013726|DRUG: AG-013736 (axitinib)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Restless Legs Symptoms With Pramipexole to Improve the Outcomes of Protracted Opioid Withdrawal in OUD
Status: RECRUITING
Conditions: Sleep Disorder|Restless Legs Syndrome|Opioid-use Disorder|Opioid Withdrawal
Interventions: DRUG: Pramipexole|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial Investigating the Safety, Tolerability and Efficacy of TransCon PTH Administered Daily in Adults With Hypoparathyroidism
Status: ACTIVE_NOT_RECRUITING
Conditions: Hypoparathyroidism|Endocrine System Diseases|Parathyroid Diseases
Interventions: COMBINATION_PRODUCT: TransCon PTH|COMBINATION_PRODUCT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Interstitial Brachytherapy Using Diffusing Alpha Emitters Radiation Therapy in Men With Prostate Cancer
Status: RECRUITING
Conditions: Prostate Adenocarcinoma
Interventions: DEVICE: Radiation: Diffusing Alpha Radiation Emitters Therapy (DaRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Efficacy of TS-091 in Patients With Narcolepsy
Status: COMPLETED
Conditions: Narcolepsy
Interventions: DRUG: TS-091 5mg|DRUG: TS-091 10mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Palmitoylethanolamide-polydatin Combination on Chronic Pelvic Pain in Patients With Endometriosis
Status: COMPLETED
Conditions: Endometriosis|Chronic Pelvic Pain
Interventions: DRUG: Administration of micronized Palmitoylethanolamide (PEA)- Transpolydatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Apixaban in Malignancy With Deep Venous Thrombosis
Status: UNKNOWN
Conditions: Deep Vein Thrombosis|Malignancy
Interventions: DRUG: Apixaban|DRUG: Enoxaparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Long Term Safety of Clopidogrel in Neonates/Infants With Systemic to Pulmonary Artery Shunt Palliation
Status: COMPLETED
Conditions: Heart Defects, Congenital
Interventions: DRUG: Clopidogrel|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Analgesic Effect of Perioperative Systemic Lidocaine in Patients Undergoing Unilateral Mastectomy Surgery
Status: TERMINATED
Conditions: Pain
Interventions: DRUG: Lidocaine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Clinical Effectiveness of Non-contact Heart Rate and Respiratory Rate Monitoring System
Status: NOT_YET_RECRUITING
Conditions: Sleep|Infant，Newborn|Vital Signs
Interventions: DEVICE: Non-contact heart rate and respiratory rate monitoring system|DEVICE: Mindray ECG monitor|DEVICE: aEEG|OTHER: Neonatal Sleep-Wake Assessment Tool (NSWAT) included four dimensions: eye movement, respiratory rate, facial expression and muscle activity.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Researching the Effects of Sepsis on Quality Of Life, Vitality, Epigenome and Gene Expression During RecoverY From Sepsis
Status: ENROLLING_BY_INVITATION
Conditions: Sepsis|Infection
Interventions: OTHER: Exposure of interest: study DNA methylation (epigenetics) and gene expression (transcriptomics) of blood leukocytes
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of LY3002813 in Participants With Early Symptomatic Alzheimer's Disease (TRAILBLAZER-ALZ)
Status: COMPLETED
Conditions: Alzheimer Disease
Interventions: DRUG: Donanemab|DRUG: Placebo|DRUG: LY3202626
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study to Examine the Role of Nitazoxanide to Prevent Recurrence of Hepatitis C After Transplantation
Status: COMPLETED
Conditions: Hepatitis C Recurrence
Interventions: DRUG: Nitazoxanide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Novel Approaches in Preventing and Limiting Events III Trial (NAPLES III): Bivalirudin in High-risk Bleeding Patients
Status: COMPLETED
Conditions: Bleeding
Interventions: DRUG: Bivalirudin|DRUG: Unfractionated Heparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: CARD for Community Pharmacy Vaccinations
Status: NOT_YET_RECRUITING
Conditions: Vaccination Reaction|Vaccination Pain|Community Pharmacy
Interventions: BEHAVIORAL: CARD (Comfort Ask Relax Distract)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial to Assess the Efficacy and Safety of 400mg/Day Lacosamide in Subjects With Painful Diabetic Neuropathy
Status: COMPLETED
Conditions: Painful Diabetic Neuropathy
Interventions: DRUG: SPM 929|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Significance of Deviation in Time From the 12-hour Standard Serum-clozapine Monitoring.
Status: COMPLETED
Conditions: Schizophrenia
Interventions: PROCEDURE: Blood sampling|DRUG: Clozapine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Residual Disease Driven Strategy for CARCIK (CD19) in Adults/Pediatric BCP-ALL
Status: RECRUITING
Conditions: Acute Lymphoblastic Leukemia
Interventions: GENETIC: PTG-CARCIK-CD19
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Systems Approach to Predict the Outcome of SARS-CoV-2 in the Population of a City; COVID-19
Status: COMPLETED
Conditions: SARS Coronavirus (SARS-CoV-2) Infection
Interventions: OTHER: Study A|OTHER: Study B|OTHER: Study C|OTHER: Study D
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Cord Blood Stem Cell Transplantation Study (COBLT)
Status: COMPLETED
Conditions: Anemia, Aplastic|Fanconi Anemia|Hematologic Diseases|Leukemia|Neoplasms|Severe Combined Immunodeficiency|Hematopoietic Stem Cell Transplantation|Myelodysplastic Syndromes
Interventions: PROCEDURE: stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Treatment of Acute Sinusitis
Status: COMPLETED
Conditions: Acute Respiratory Infections|Acute Rhinosinusitis
Interventions: DRUG: Acetaminophen|DRUG: Amoxicillin|DRUG: Dextromethorphan hydrobromide with guaifenesin|DRUG: Guaifenesin|DRUG: Pseudoephedrine Sustained Action|DRUG: Saline spray (0.65%)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Evaluation of the Biodistribution and Imaging Characteristics of ABT-806i (111In-ABT-806) in Subjects With Advanced Solid Tumor Types
Status: COMPLETED
Conditions: Advanced Solid Tumors
Interventions: DRUG: ABT-806|DRUG: ABT-806i
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Combination Radiotherapy and Radiopharmaceutical Therapy Treatment Planning for Thyroid Cancer
Status: RECRUITING
Conditions: Recurrent Thyroid Cancer
Interventions: COMBINATION_PRODUCT: Combination treatment (CXRPT) of external beam radiation (XRT) plus radioactive iodine (RAI)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EPR (Electron Paramagnetic Resonance) as Method of Non-invasive Characterization of Melanin Content in Skins With Different Phototypes
Status: COMPLETED
Conditions: Skin Pigmentation|Free Radicals|Phototype|Magnetic Resonance
Interventions: DEVICE: EPR measurement
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Patient-Controlled Cognitive-Behavioral Intervention for Cancer Symptoms
Status: COMPLETED
Conditions: Pain|Fatigue|Sleep Disturbance|Cancer
Interventions: BEHAVIORAL: Patient-Controlled Cognitive-Behavioral Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Trial To Assess Risk of Delirium in Older Adults Undergoing Hip Fracture Surgery With Spinal or General Anesthesia
Status: COMPLETED
Conditions: Postoperative Complications|Hip Fracture|Delirium
Interventions: OTHER: General endotracheal anesthesia|OTHER: Regional (spinal) Anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Apple and Apple Pomace on Inflammation and Cholesterol Metabolism in Healthy Overweight
Status: COMPLETED
Conditions: Cardiovascular Diseases
Interventions: DIETARY_SUPPLEMENT: Apples|DIETARY_SUPPLEMENT: Apple pomace
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Upfront Immune Checkpoint Inhibitors With Deferred Cytoreductive Nephrectomy for Metastatic Renal Cell Carcinoma
Status: NOT_YET_RECRUITING
Conditions: Clear-cell Metastatic Renal Cell Carcinoma|Immune Checkpoint Inhibitors|Cytoreductive Nephrectomy
Interventions: DRUG: Toripalimab|PROCEDURE: Cytoreductive Nephrectomy|DRUG: Axitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of a High Fat Breakfast in the Pharmacokinetics of UH-AC62MU in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: meloxicam rapid release tablet, 12mg, UH AC62MU
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SimpleC Wellness Platform With Social Robot Interaction (Long-term)
Status: COMPLETED
Conditions: Engagement, Patient|Quality of Life|Mood|Aging Well|Cognitive Change|Mild Cognitive Impairment|Cognitive Impairment|Dementia
Interventions: BEHAVIORAL: Behavioral Interventions|BEHAVIORAL: Robot Interventions
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Sulforaphane for Patients With Chronic Kidney Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Kidney Disease
Interventions: DIETARY_SUPPLEMENT: L-sulforaphane 1%|DIETARY_SUPPLEMENT: Placebo Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Anaemia Correction in Haemodialyzed Patients - Comparative Analysis of Two Erythropoietin Stimulating Agents Schedules
Status: WITHDRAWN
Conditions: Bio-Equivalency of 2 Treatment Schedules in HD Patients
Interventions: DRUG: switch (epoetinum beta, darbepoetinum)|DRUG: continuation (darbepoetinum)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Association Between Cerebral Arterial Vascular Flow and Sleep Apnea in Neurodegenerative Alterations
Status: UNKNOWN
Conditions: Alzheimer Disease
Interventions: OTHER: Vascular flow measurement by PC-MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: 18F-mFBG Expression in Neural Crest Tumors and Organs Innervated by the Sympathetic Nervous System
Status: NOT_YET_RECRUITING
Conditions: Neuroblastoma|Pheochromocytoma|Paraganglioma
Interventions: DRUG: 18F-mFBG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Use of Photobiomodulation in the Management of Radiodermatitis in Patients in Palliative Care. A Prospective Study.
Status: WITHDRAWN
Conditions: Radiodermatitis; Acute|Radiotherapy Side Effect|Cancer Patients|Palliative Care
Interventions: RADIATION: Photobiomodulation Therapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: WBRT With Hippocampal-avoidance Technique Followed by SRT for Extensive-stage SCLC With Baseline Brain Metastases
Status: RECRUITING
Conditions: SCLC,Extensive Stage|Brain Metastases
Interventions: RADIATION: HA-WBRT plus SBRT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Efficacy and Safety of Abametapir Lotion Administered for the Treatment of Head Lice Infestation
Status: COMPLETED
Conditions: Head Lice Infestation
Interventions: DRUG: Abametapir Lotion 0.74% w/w|DRUG: Vehicle Lotion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Pharmacokinetics and Pharmacodynamics of NBI-77860 in Adolescent Females With Congenital Adrenal Hyperplasia
Status: WITHDRAWN
Conditions: Congenital Adrenal Hyperplasia
Interventions: DRUG: NBI-77860|DRUG: NBI-77860|DRUG: NBI-77860
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A New Method for Colorectal Cancer Screening: Colon Capsule Endoscopy Compared to Conventional Endoscopy
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: PROCEDURE: Colon capsule endoscopy|PROCEDURE: Conventional Colonoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Filipino Family Health Initiative 1.0
Status: NOT_YET_RECRUITING
Conditions: Depression|Anxiety|Parenting
Interventions: BEHAVIORAL: Incredible Years® School Age Basic Parent Training Program|BEHAVIORAL: American Academy of Pediatrics, Bright Futures Handouts
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: DIgital Assisted MONitoring for DiabeteS - I
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: PROCEDURE: Use of software-implemented glucometer for real-time collection and transmission of measured glucose values to remote server.|PROCEDURE: Use of regular glucometer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Polymorphisms of Fibrosis-Relating Genes on Outcome of HCV-Related Chronic Liver Disease
Status: COMPLETED
Conditions: Fibrosis|Chronic Liver Disease
Interventions: GENETIC: cytokine|GENETIC: cytokine polymorphisms|GENETIC: cytokine polymorphism
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Expansion Study of a Simplified Regimen of Medical Abortion Thru 63 Last Menstrual Period (LMP) in Tunisia
Status: COMPLETED
Conditions: Induced Abortion
Interventions: DRUG: Mifepristone, misoprostol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: ASSessing the Effect of Anti-IL-6 Treatment in Myocardial Infarction: The ASSAIL-MI Trial
Status: COMPLETED
Conditions: Coronary Disease|Myocardial Infarction
Interventions: DRUG: Tocilizumab|DRUG: Sodium chloride 0.9%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of KRT-232 or TL-895 in Janus Associated Kinase Inhibitor Treatment-Naïve Myelofibrosis
Status: RECRUITING
Conditions: Primary Myelofibrosis (PMF)|Post-Polycythemia Vera Myelofibrosis (Post-PV-MF)|Post-Essential Thrombocythemia Myelofibrosis (Post-ET-MF)
Interventions: DRUG: KRT-232|DRUG: TL-895
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CPAP Effect on the Polycythemia in Patients With Obstructive Sleep Apnea
Status: RECRUITING
Conditions: Sleep Apnea, Obstructive|Polycythemia
Interventions: DEVICE: Continuous positive airway pressure|DRUG: Conventional pharmacological treatment|OTHER: Sleep ,diet and life style recomendations
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Left and Right Transradial Approach for CAG and PCI
Status: COMPLETED
Conditions: Coronary Artery Disease|Stable Angina|Unstable Angina|Non-ST Elevation Myocardial Infarction|ST-segment Elevation Myocardial Infarction|Ischemic Heart Disease Without Angina
Interventions: PROCEDURE: Radial approach
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: COVID-19 Vaccination Using a 2nd Generation (E1/E2B/E3-Deleted) Adenoviral Platform in Healthy South African Adults
Status: ACTIVE_NOT_RECRUITING
Conditions: Covid19
Interventions: BIOLOGICAL: hAd5-S-Fusion+N-ETSD vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Zoledronic Acid in Patients With Renal Cell Cancer and Bone Metastasis
Status: COMPLETED
Conditions: Renal Cell Cancer|Neoplasm Metastasis
Interventions: DRUG: Zoledronic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Investigate the Therapeutic Effect of Aculife Magnetic Therapist on Carpal Tunnel Syndrome
Status: UNKNOWN
Conditions: Carpal Tunnel Syndrome
Interventions: DEVICE: Aculife Magnetic Wave Therapist|DEVICE: TENS
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Telephone-based Motivational Interviewing for Smoking Cessation in Crohn's Disease Patients
Status: COMPLETED
Conditions: Crohn Disease
Interventions: BEHAVIORAL: Telephone-based motivational interviewing for smoking cessation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE