pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Component Analysis for Motivational Interviewing
Status: COMPLETED
Conditions: Alcohol-Related Disorders|Alcohol Use Disorders|Alcohol Drinking|Alcoholism|Alcohol Abuse
Interventions: BEHAVIORAL: Full Motivational Interviewing ("FMI")|BEHAVIORAL: Spirit Only Motivational Interviewing ("SOMI")
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Whether 2 New Oral Formulations of a Strong Pain Killer Release the Same Amount of Drug Into the Body as the Marketed Medication
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Active comparator MR2XXX|DRUG: MRXXX|DRUG: MR1XXX|DRUG: MRXXX and MR1XXX
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Progesterone on Testosterone Concentrations and Breast Development in Transwomen
Status: TERMINATED
Conditions: Transgender Persons
Interventions: DRUG: Progesterone 200 MG|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Periodontal Treatment on Gastric Helicobacter Pylori Eradication
Status: COMPLETED
Conditions: Helicobacter Pylori Infection
Interventions: DRUG: Triple therapy|PROCEDURE: professional periodontal treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Protocol for the Use of Chlorhexidine Gluconate Saturation for the Reduction of Dental Biofilm Formation on Polymethylmethacrylate Restoration
Status: COMPLETED
Conditions: Dental Plaque
Interventions: PROCEDURE: saturation of polymethylmethacrylate with chlorhexidine gluconate to reduce in vivo plaque formation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE|Primary Purpose: PREVENTION
Clinical trial: Bioavailability and Bioequivalence of Two Risdiplam Tablets in Healthy Participants
Status: COMPLETED
Conditions: Muscular Atrophy, Spinal
Interventions: DRUG: risdiplam|DRUG: omeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Platelet-rich Plasma Intra-articular Knee Injections for Knee Osteoarthritis
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: BIOLOGICAL: platelet-rich plasma|DRUG: Corticosteroid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase IIa Multicentre Study Investigating of VR040 in Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DRUG: VR040/Aspirair® inhaler|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The INITIATE Study: Initiating Nicotine Dependence Treatment for Smokers Admitted to Emergency Departments
Status: RECRUITING
Conditions: Nicotine Dependence, Cigarettes|Nicotine Withdrawal
Interventions: BEHAVIORAL: Quit Card Intervention (QCI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Amiodarone Compared to Dronedarone , Post Cardioversion Maintenance of Sinus Rhythm
Status: UNKNOWN
Conditions: Atrial Fibrillation
Interventions: DRUG: amiodarone|DRUG: Dronedarone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intranasal Ketorolac Versus Intravenous Ketorolac for Treatment of Migraine Headaches in Children
Status: COMPLETED
Conditions: Migraine
Interventions: DRUG: Ketorolac, intranasal|DRUG: Ketorolac, intravenous|DRUG: Placebo, intravenous|DRUG: Placebo, intranasal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Therapeutic Confirmatory Study to Evaluate the Efficacy and Safety of Avanafil
Status: COMPLETED
Conditions: Erectile Dysfunction
Interventions: DRUG: Avanafil|DRUG: Avanafil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PEAK Platelet Rich Plasma Injection Treatment for Chronic Lateral Epicondylosis
Status: COMPLETED
Conditions: Chronic Lateral Epicondylosis
Interventions: BIOLOGICAL: Platelet Rich Plasma - Group 1|DRUG: Corticosteroid Control - Group 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Predicting Risk for Post-polypectomy Colorectal Cancer
Status: WITHDRAWN
Conditions: Colorectal Cancer|Colorectal Polyp|Colorectal Adenoma|Neoplasm, Colorectal
Interventions: DEVICE: Logistic regression risk model
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: An Evaluation of Divalproex vs. Olanzapine for Alcohol Abuse Relapse Prevention in Patients With Bipolar Disorder
Status: WITHDRAWN
Conditions: Bipolar Disorder
Interventions: DRUG: divalproex or olanzapine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Safety, Reactogenicity and Immunogenicity of Adenovirus Serotype 26 (Ad26)- and Modified Vaccinia Ankara (MVA)-Vectored Vaccine Components in Otherwise Healthy Women With HPV16 or HPV18 Infection of the Cervix
Status: TERMINATED
Conditions: Human Papillomavirus Infections
Interventions: BIOLOGICAL: Ad26.HPV16|BIOLOGICAL: Ad26.HPV18|BIOLOGICAL: MVA.HPV16/18|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of RIC on TIA/Stroke in Children With Moyamoya Disease
Status: UNKNOWN
Conditions: Moyamoya Disease|TIA|Children|Stroke
Interventions: DEVICE: RIC group|DEVICE: Sham group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Treatment of Impaired Glucose Tolerance in Pregnancy
Status: COMPLETED
Conditions: Impaired Glucose Tolerance|Fetal Macrosomia
Interventions: DRUG: Insulin aspart and Insulin human (isophane)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Study of Sequential High-dose Chemotherapy in Children With High Risk Medulloblastoma
Status: TERMINATED
Conditions: High-risk Medulloblastoma
Interventions: DRUG: Carboplatin + etoposide|DRUG: Thiotepa|DRUG: Cyclophosphamide + Busilvex|DRUG: Temozolimide + Irinotecan|COMBINATION_PRODUCT: Etoposide + radiotherapy|DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Proprioception in Patients Treated With Surgical External Ankle Ligament Recontruction for Traumatic Ankle Instability
Status: COMPLETED
Conditions: Ankle Sprains|Instability, Joint
Interventions: DEVICE: Delos instrument (computerized balance board)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy & Safety Study of Nonracemic Methadone for the Relief of Chronic Peripheral Neuropathic Pain
Status: COMPLETED
Conditions: Diabetic Peripheral Neuropathic Pain
Interventions: DRUG: Non-racemic mixture of methadone HCl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Two Drugs (Propofol and Nitroglycerin as a Hypotensive Agents During Endoscopic Sinus Surgery
Status: TERMINATED
Conditions: Hypotensive Anesthesia
Interventions: DRUG: Propofol|DRUG: Nitroglycerin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Effects of Using Betahistine to Treat Adults With Attention Deficit Hyperactivity Disorder
Status: COMPLETED
Conditions: Attention Deficit Disorder With Hyperactivity
Interventions: DRUG: Betahistine Hydrochloride|DRUG: Placebo Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of UC-MSCs for the Treatment of Steroid-resistant aGVHD Following Allo-HSCT
Status: COMPLETED
Conditions: Graft Vs Host Disease
Interventions: DRUG: UC-MSC|DRUG: Anti-CD25 mAb
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bromfenac BID Plus Prednisolone Acetate BID Versus Bromfenac BID Plus Prednisolone QID for the Prevention of Cystoid Macular Edema and Retinal Thickening
Status: COMPLETED
Conditions: Cystoid Macular Edema,|Retinal Thickening
Interventions: DRUG: 2. Xibrom (Bromfenac)|DRUG: 1. Pred Forte
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The SITE Study - Dexamethasone Ophthalmic Insert In OR on Day of Surgery Versus In-office Post-Op Day 1
Status: COMPLETED
Conditions: Cataract
Interventions: DRUG: Dexamethasone 0.4 MG [Dextenza]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Research Into the Effect of a Clot-dissolving Agent and Its Inhibitor
Status: TERMINATED
Conditions: Acute Ischemic Stroke
Interventions: DRUG: M5|DRUG: C1-inhibitor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Psychopathological Differences Between Asperger Syndrome and Schizotypal Disorder in an Adult Sample
Status: COMPLETED
Conditions: Asperger Syndrome|Autism Spectrum Disorder|Schizotypal Personality Disorder
Interventions: OTHER: Expert panel evaluation|OTHER: Semi-structured psychopathological interviews|OTHER: Self-administered rating scales|OTHER: Other general interviewer ratings
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Intraperitoneal Local Anesthetic in Bariatric Surgery Study (iLABS Study)
Status: COMPLETED
Conditions: Overweight and Obesity|Bariatric Surgery Candidate
Interventions: DRUG: Ropivacaine|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect Of Complete Decongestive Therapy On Carpal Tunnel Syndrome Post Upper Limb Lymphedema
Status: NOT_YET_RECRUITING
Conditions: Lymphedema
Interventions: OTHER: Complete decongestive therapy|OTHER: Medical treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Steroids in Total Knee Arthroplasty
Status: TERMINATED
Conditions: Postoperative Pain|Inflammation|Osteoarthritis
Interventions: DRUG: Dexamethasone 10 mg|DRUG: Dexamethasone 20 mg|DRUG: Standard multimodal pain management regimen|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Efficacy and Safety of Camrelizumab and Famitinib in Patients With Advanced Solid Tumor
Status: COMPLETED
Conditions: Solid Tumor
Interventions: DRUG: Camrelizumab|DRUG: Famitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Attention Deficit Hyperactivity Disorder Knowledge Improvement Program on Male Primary School Teachers
Status: UNKNOWN
Conditions: ADHD|Mental Disorder|Attention Deficit Hyperactivity Disorder
Interventions: OTHER: Knowledge Improvement Program about ADHD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Comparative Study Between Fluticasone Furoate/Umeclidinium/Vilanterol (FF/UMEC/VI) Single Inhaler Triple Therapy Versus Tiotropium Monotherapy in Subjects With Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: FF/UMEC/VI|DRUG: Tiotropium|DRUG: Albuterol/salbutamol|DRUG: Placebo to match FF/UMEC/VI|DRUG: Placebo to match tiotropium|DEVICE: ELLIPTA inhaler|DEVICE: HANDIHALER|DEVICE: MDI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Propofol + Remifentanil vs. Propofol + Dexmedetomidine in Adolescent Idiopathic Scoliosis Patients Having Spine Surgery
Status: RECRUITING
Conditions: Adolescent Idiopathic Scoliosis|Multimodal Analgesia|Opioid Induced Hyperalgesia|Remifentanil|Dexmedetomidine|Posterior Spinal Fusion
Interventions: DRUG: Remifentanil TIVA|DRUG: Dexmedetomidine TIVA|DRUG: Propofol TIVA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Ilaprazole for the Treatment and Prevention of Peptic Ulcer Bleeding in Chinese Patients
Status: COMPLETED
Conditions: Peptic Ulcer Hemorrhage
Interventions: DRUG: Ilaprazole|DRUG: Omeprazole|DRUG: Ilaprazole tablet|DRUG: amoxicillin and clarithromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Anti-inflammatory Effects of Colchicine in PCI
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DRUG: Colchicine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Using Decision Aids to Reducing Decision Conflict in Angiography Patients for Choosing Hemostasis
Status: UNKNOWN
Conditions: Haemostatic Adverse Reaction
Interventions: OTHER: Decision aids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Safety, Feasibility and Oncological Outcomes of Laparoscopic Completion Total Gastrectomy for Remnant Gastric Cancer
Status: ENROLLING_BY_INVITATION
Conditions: Remnant Gastric Cancer
Interventions: PROCEDURE: Laparoscopic completion total gastrectomy with D2 lymphadenectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Renin-Angiotensin-Aldosterone System and Parathyroid Hormone Control: The RAAS-PARC Study
Status: COMPLETED
Conditions: Hyperparathyroidism
Interventions: DRUG: Lisinopril
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Nab-pacliatxel Plus Gemcitabine in Korean Patients With Metastatic Pancreatic Ductal Adenocarcinoma
Status: COMPLETED
Conditions: Pancreatic Ductal Adenocarcinoma
Interventions: DRUG: nab-paclitaxel|DRUG: gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Human Monoclonal Antibody to Treat Mycosis Fungoides and Sezary Syndrome
Status: TERMINATED
Conditions: Mycosis Fungoides|Sezary Syndrome
Interventions: DRUG: HuMax-CD4 (zanolimumab)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical and Radiographic Evaluation of Indirect Pulp Capping in Primary and Permanent Teeth With Different Materials
Status: COMPLETED
Conditions: Dental Pulp Capping
Interventions: DRUG: Calcium Hydroxide|DRUG: Mineral Trioxide Aggregate|DRUG: TheraCal LC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: MLC901 in Moderate Traumatic Brain Injury
Status: RECRUITING
Conditions: Moderate Traumatic Brain Injury
Interventions: DIETARY_SUPPLEMENT: MLC901|GENETIC: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial for Evaluation of Clinical Efficacy and Safety of Healing Stone Navel Belt in Patients With Primary Dysmenorrhea
Status: UNKNOWN
Conditions: Primary Dysmenorrhea
Interventions: DEVICE: Healingstone navel belt
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Different Doses of Venus Association in Patients With Vulvovaginal Candidiasis.
Status: WITHDRAWN
Conditions: Vulvovaginal Candidiasis
Interventions: DRUG: Venus 20 + 0,064|DRUG: Venus 20 + 1|DRUG: Venus 20 + 4|DRUG: Butoconazole nitrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Optimizing Chronic Pain Treatment With Enhanced Neuroplastic Responsiveness
Status: COMPLETED
Conditions: Pain|Osteoarthritis
Interventions: OTHER: Glucose Administration|OTHER: Intermittent Fasting|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Impact of Virtual Reality in Pediatric Hematology and Oncology
Status: RECRUITING
Conditions: Virtual Reality|Pediatrics|Cancer|Pain|Procedural Pain
Interventions: DEVICE: Virtual Reality|DRUG: Usual Practices
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Sub Arachnoid Neurocysticercosis Treatment Outcome (SANTO)
Status: TERMINATED
Conditions: Neurocysticercosis
Interventions: DRUG: Albendazole and praziquantel|DRUG: Albendazole and praziquantel placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pain Injection Versus Epidural Anesthesia for Hip Surgery in Pediatric Patients With Cerebral Palsy
Status: RECRUITING
Conditions: Cerebral Palsy|Hip Dysplasia|Pain, Postoperative
Interventions: DRUG: Ropivacaine injection|DRUG: Bupivacaine, lidocaine, ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A High-resolution Peripheral Quantitative Computed Tomography Study in Postmenopausal Women Previously Treated With Denosumab
Status: COMPLETED
Conditions: Low Bone Mass|Low Bone Mineral Density|Osteoporosis|Postmenopausal Osteoporosis
Interventions: PROCEDURE: high-resolution peripheral quantitative computed tomography (HR-pQCT)|PROCEDURE: Dual energy X-ray absorptiometry (DXA)|BIOLOGICAL: Denosumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Airborne Ultrafine and Fine Particulate Matter: A Cause for Endothelial Dysfunction in Man?
Status: COMPLETED
Conditions: Airway Inflammation
Interventions: OTHER: placebo|DRUG: Montelukast
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Ketorolac for Analgesia followiNG Autologous Breast RecOnstructiOn
Status: WITHDRAWN
Conditions: Breast Cancer Female
Interventions: DRUG: Ketorolac Tromethamine|DRUG: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Baricitinib (LY3009104) in Adult Participants With Moderate to Severe Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: Baricitinib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of Metformin Glycinate on Postprandial Lipemia
Status: UNKNOWN
Conditions: Type 2 Diabetes
Interventions: DRUG: Metformin glycinate|DRUG: Metformin Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Arformoterol Tartrate Inhalation Solution and Tiotropium Bromide on Re-hospitalization in Chronic Obstructive Pulmonary Disease (COPD) Subjects
Status: TERMINATED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: DRUG: Arformoterol tartrate inhalation solution|DRUG: Tiotropium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Implementation of PED-t in a Naturalistic Setting
Status: COMPLETED
Conditions: Bulimia Nervosa|Binge-Eating Disorder
Interventions: BEHAVIORAL: Physical exercise and dietary therapy (PED-t)|PROCEDURE: Implementation program for PED-t in ERC
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Neoadjuvant Chemo-hypoRT Plus PD-1 Antibody (Tislelizumab) in Resectable LA-G/GEJ
Status: ACTIVE_NOT_RECRUITING
Conditions: Gastric or Gastroesophageal Junction Adenocarcinoma
Interventions: COMBINATION_PRODUCT: neoadjuvant chemo-hypofractionated radiotherapy plus PD-1 antibody (Tislelizumab)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral Gabapentin in the Treatment of Carpal Tunnel Syndrome
Status: UNKNOWN
Conditions: Carpal Tunnel Syndrome
Interventions: DRUG: Gabapentin oral capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Role of Left Prefrontal Transcranial Magnetic Stimulation in Episodic Migraine Prophylaxis
Status: COMPLETED
Conditions: Episodic Migraine|Prophylaxis
Interventions: DEVICE: repetitive transcranial magnetic stimulation (rTMS) 100% motor threshold|DEVICE: repetitive transcranial magnetic stimulation (rTMS) 50% motor threshold
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of Inhaled Zanamivir in Treatment of Influenza A and B Virus Infections in China
Status: COMPLETED
Conditions: Influenza A Virus Infection|Influenza B Virus Infection
Interventions: DRUG: Zanamivir|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Case Selection and Treatment Protocol for Immediate Dental Implants in the Esthetic Zone
Status: COMPLETED
Conditions: Jaw, Edentulous, Partially|Acquired Absence of Single Tooth
Interventions: DEVICE: SLActive implant
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Phase 2 Study Whole Brain Radiation Therapy With Simultaneous Integrated Boost for Patients With Brain Metastases
Status: TERMINATED
Conditions: Brain Metastases
Interventions: RADIATION: Cohort A|RADIATION: Cohort B
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Probiotics and Nutritional Status on Exercise-Induced Symptoms, and Endurance Performance in Ultra-Endurance Athletes
Status: COMPLETED
Conditions: Ultra-endurance Athletes With Gastrointestinal Symptoms
Interventions: DIETARY_SUPPLEMENT: Oral Rehydration Salts supplemented with L. Rhamnosus GG|DIETARY_SUPPLEMENT: Oral Rehydration Salts only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Prothrombin Complex Concentrate Reducing Perioperative Blood Loss in Cardiac Surgery
Status: NOT_YET_RECRUITING
Conditions: Cardiac Surgical Procedures
Interventions: DRUG: Prothrombin Complex Concentrate, Human|DRUG: Fresh Frozen Plasma
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: WENBIT - Western Norway B Vitamin Intervention Trial
Status: COMPLETED
Conditions: Coronary Artery Disease|Myocardial Infarction|Cerebrovascular Stroke
Interventions: DRUG: folic acid, vitamin B12 (cyanocobalamin), vitamin B6 (pyridoxine)|DRUG: folic acid, vitamin B12 (cyanocobalamin)|DRUG: vitamin B6 (pyridoxine)|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Hysterotomy Technique on the Rate of Large Defects in the Hysterotomy Scar
Status: COMPLETED
Conditions: Scars
Interventions: PROCEDURE: hysterotomy at cesarean
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Evaluation of Oral Midazolam in First-trimester Surgical Abortions
Status: COMPLETED
Conditions: Pain|Anxiety|Nausea
Interventions: DRUG: Midazolam|DRUG: Ibuprofen|OTHER: Placebo-Cherry syrup|DRUG: Lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: L-arginine in Severe Asthma Patients Grouped by Exhaled Nitric Oxide Levels
Status: COMPLETED
Conditions: Asthma|Inflammation
Interventions: DRUG: L-Arginine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy & Safety Study Comparing Misoprostol Vaginal Insert (MVI) Versus Dinoprostone Vaginal Insert (DVI) for Reducing Time to Vaginal Delivery
Status: COMPLETED
Conditions: Reducing Time to Vaginal Delivery|Cervical Ripening|Induction of Labor
Interventions: DRUG: MVI 200|DRUG: Dinoprostone Vaginal Insert (DVI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Microparticle Generation After Laparoscopic Surgical Treatment for Endometrioma.
Status: COMPLETED
Conditions: Microparticle|Endometriosis|Laparoscopy
Interventions: PROCEDURE: Stripping versus laser CO2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study to Evaluate the Efficacy and Tolerability of Venaflon Use in Reducing the Symptoms Caused by Chronic Venous Insufficiency When Compared With Daflon
Status: UNKNOWN
Conditions: Chronic Venous Insufficiency|Disease
Interventions: DRUG: Daflon|DRUG: Venaflon (Diosmin and Hesperidin)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Combination of MK3475 and Metronomic Cyclophosphamide in Patients With Advanced Sarcomas : Multicentre Phase II Trial
Status: UNKNOWN
Conditions: Sarcoma
Interventions: DRUG: Combination of MK3475 with Metronomic CP|DRUG: Combination of MK3475 with Metronomic CP and G100
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: OC000459 Dose Finding Study in Hay Fever Sufferers.
Status: COMPLETED
Conditions: Allergic Rhinitis
Interventions: DRUG: OC000459|DRUG: OC000459|DRUG: OC000459|DRUG: OC000459|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Exercise Capacity and Quality of Life in Patients With PPH Receiving Short Term Oral L-Citrulline Malate
Status: UNKNOWN
Conditions: Idiopathic Pulmonary Arterial Hypertension|Eisenmenger Syndrome
Interventions: DRUG: L-Citrulline Malate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Effects of Dietary Fibre on Glucose Metabolism and Satiety
Status: COMPLETED
Conditions: Obesity|Metabolic Syndrome
Interventions: OTHER: Test meal|OTHER: Reference|OTHER: Priming|OTHER: No priming
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Longitudinal Trial Assessing Cellulite in Women Wearing a New Compression Garment
Status: RECRUITING
Conditions: Cellulite
Interventions: DEVICE: Compression garment with Vari-pad microdots ink-printed on inside.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: COMBO-Stent in Patients on Chronic Anticoagulant Therapy (COSTA) COSTA-Bleed and COSTA-Outcome Trials
Status: WITHDRAWN
Conditions: Stable Angina|Unstable Angina|STEMI|NSTEMI|Coronary Disease
Interventions: DEVICE: COMBO-Stent|DRUG: Clopidogrel, Vitamin K Antagonist, Rivaroxaban, Dabigatran|DEVICE: Any drug eluting stent oder bare metal sent|DRUG: ASA, Clopidogrel, Vitamin K Antagonist, Rivaroxaban, Dabigatran
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Treatment of Glabellar Frown Lines
Status: COMPLETED
Conditions: Glabellar Frown Lines
Interventions: DRUG: IncobotulinumtoxinA|DRUG: OnabotulinumtoxinA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of KD025 in Subjects With cGVHD After At Least 2 Prior Lines of Systemic Therapy
Status: TERMINATED
Conditions: Chronic Graft-versus-host-disease
Interventions: DRUG: Belumosudil (KD025)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Osimertinib With Bevacizumab for Leptomeningeal Metastasis From EGFR-mutation Non-Small Cell Lung Cancer
Status: UNKNOWN
Conditions: Leptomeningeal Metastasis|Non-small Cell Lung Cancer|EGFR Activating Mutation
Interventions: DRUG: Osimertinib|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adjunctive Treatment of Chronic Migraine Using an Oral Dental Device
Status: COMPLETED
Conditions: Chronic Migraine, Headache
Interventions: DEVICE: NTI-tss|DEVICE: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Multicenter Clinical Study of Apatinib Mesylate Combined With Doctor's Choice for Advanced Breast Cancer
Status: NOT_YET_RECRUITING
Conditions: Advanced Breast Cancer
Interventions: DRUG: apatinib mesylate+Capecitabine Tablets|DRUG: apatinib mesylate+Fulvestrant injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: "Efficacy of Once Weekly GLP 1 Analogue: Semaglutide. A Multicenter Experience From Pakistan."
Status: UNKNOWN
Conditions: Diabetes Mellitus, Type 2|Weight Change, Body
Interventions: DRUG: Semaglutide Pen Injector
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: IVR-Enhanced Care Transition Support for Complex Patients
Status: COMPLETED
Conditions: Congestive Heart Failure|Chronic Obstructive Pulmonary Disease
Interventions: BEHAVIORAL: IVR-Enhanced Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: An Early Bactericidal Activity, Safety and Tolerability of GSK3036656 in Subjects With Drug-sensitive Pulmonary Tuberculosis
Status: COMPLETED
Conditions: Tuberculosis
Interventions: DRUG: GSK3036656|DRUG: Rifafour e-275
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Percutaneous Tracheostomy - Systematic Comparison Among Three Methods: Prospective Study
Status: UNKNOWN
Conditions: Other Tracheostomy Complication
Interventions: PROCEDURE: Percutaneous tracheostomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Restoration Repairs Using Composite Resin Versus Glass Ionomer in Primary Molars: a Randomized Clinical Trial
Status: UNKNOWN
Conditions: Dental Caries|Dental Caries in Children
Interventions: PROCEDURE: Encapsulated Glass Ionomer Cement|PROCEDURE: Composite resin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Donor Milk vs. Formula in Extremely Low Birth Weight (ELBW) Infants
Status: COMPLETED
Conditions: Infant, Newborn|Infant, Small for Gestational Age|Infant, Extremely Low Birth Weight
Interventions: BIOLOGICAL: Donor Milk|DIETARY_SUPPLEMENT: Preterm Formula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Investigating the Use of a Preoperative High-Arginine Nutritional Supplement Prior to Radical Cystectomy
Status: COMPLETED
Conditions: Bladder Cancer
Interventions: DIETARY_SUPPLEMENT: high arginine nutritional supplement (Nestle's Impact AR)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Evaluate VTX2735 in Patients With Cryopyrin-associated Periodic Syndrome
Status: COMPLETED
Conditions: Cryopyrin Associated Periodic Syndrome
Interventions: DRUG: VTX2735|DRUG: VTX2735
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Aerobic Exercise on Blood Pressure Levels of Resistant Hypertensive Subjects
Status: UNKNOWN
Conditions: Hypertension|Resistant Hypertension
Interventions: BEHAVIORAL: Aerobic Exercise Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of SHP465 at 6.25 mg in the Treatment of Attention-Deficit/Hyperactivity Disorder (ADHD) in Children Aged 6-12 Years
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder (ADHD)
Interventions: DRUG: SHP465|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Two Versus Four Weeks of Antibiotic Treatment in Native Joint Arthritis
Status: COMPLETED
Conditions: Arthritis, Septic
Interventions: PROCEDURE: Two week's arm - surgery|PROCEDURE: Four week's arm - surgery|DRUG: Two week's arm - drugs|DRUG: Four week's arm - drugs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Diabetes Coaching on Distress and Diabetes Self-Management
Status: NOT_YET_RECRUITING
Conditions: Diabetes Mellitus, Type 2
Interventions: BEHAVIORAL: Diabetes coaching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Multiple-Dose Pharmacokinetics and Potential for Adrenal Suppression Following Treatment With Halobetasol Spray in Patients With Plaque Psoriasis
Status: WITHDRAWN
Conditions: Plaque Psoriasis
Interventions: DRUG: Halobetasol Propionate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of the Impact of Perioperative Administration of Tranexamic Acid on Bleeding After Sleeve Gastrectomy
Status: COMPLETED
Conditions: Hemorrhage, Surgical|Bariatric Surgery|Tranexamic Acid
Interventions: DRUG: Administration of 1g tranexamic acid intravenous bolus, after anesthesia was introduced
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase Ib Study Evaluating the Safety and Tolerability of Vitamin C in Patients With Intermediate or High Risk Myelodysplastic Syndrome With TET2 Mutations
Status: COMPLETED
Conditions: Myelodysplastic Syndromes
Interventions: DRUG: Vitamin C
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: IRDye800CW-BBN PET-NIRF Imaging Guiding Surgery in Patients With Lower Grade Glioma
Status: COMPLETED
Conditions: Glioma
Interventions: DRUG: 68Ga-BBN-IRDye800CW
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy of VTP-300 in Chronic Hepatitis B Infection
Status: RECRUITING
Conditions: Chronic Hepatitis B
Interventions: BIOLOGICAL: ChAdOx1-HBV|BIOLOGICAL: MVA-HBV|BIOLOGICAL: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Distinct Response of CD4+CD25+Foxp3+ and IL-10-secreting Type I T Regulatory Cells to Cluster Specific Immunotherapy in Allergic Rhinitis Children
Status: COMPLETED
Conditions: Allergic Rhinitis|Effects of Immunotherapy
Interventions: DRUG: Dermatophagoides pteronyssinus|DRUG: Pharmacotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Assess the Efficacy, Safety and Tolerability of Rozanolixizumab in Subjects With Chronic Inflammatory Demyelinating Polyradiculoneuropathy
Status: COMPLETED
Conditions: Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP)
Interventions: DRUG: Rozanolixizumab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tumescent Antibiotic Delivery Pharmacokinetics
Status: COMPLETED
Conditions: Prevention of Surgical Site Infections
Interventions: PROCEDURE: Tumescent Antibiotic Delivery of cefazolin with or without metronidazole|PROCEDURE: Intravenous Antibiotic Delivery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: MR-targeted vs. Random TRUS-guided Prostate Biopsy
Status: UNKNOWN
Conditions: Prostate Cancer
Interventions: DEVICE: MR-guided in-bore prostate biopsy|DEVICE: TRUS-guided prostate biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Assess the Safety and Efficacy of ASP1650, a Monoclonal Antibody Targeting Claudin 6 (CLDN6), in Male Subjects With Incurable Platinum Refractory Germ Cell Tumors
Status: COMPLETED
Conditions: Incurable Platinum Refractory Germ Cell Tumors|Tumors
Interventions: DRUG: ASP1650
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial to Evaluate the Long-term Safety and Tolerability of SEP-363856 in Patients With Schizophrenia in Japan
Status: TERMINATED
Conditions: Schizophrenia
Interventions: DRUG: SEP-363856
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study of S.Flexneriza-S.Sonnei Bivalent Conjugate Vaccine in Healthy Volunteers Aged Above 3 Months
Status: COMPLETED
Conditions: Dysentery|Dysentery, Bacillary
Interventions: BIOLOGICAL: S.Flexneriza-S.Sonnei Bivalent Conjugate Vaccine|BIOLOGICAL: S.Flexneriza-S.Sonnei Bivalent Conjugate Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Need of Revisiting to an Outpatient Clinic After the Prescription of Vonoprazan or Esomeprazole
Status: RECRUITING
Conditions: Gastroesophageal Reflux
Interventions: DRUG: Vonoprazan|DRUG: Esomeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of a Pre-Workout Dietary Supplement on Training Adaptations
Status: COMPLETED
Conditions: Dietary Modification
Interventions: DIETARY_SUPPLEMENT: C4 Extreme, C4 Extreme (without Advantra Z)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Chemerin and IL-6 Levels in Diabetes and Periodontitis
Status: COMPLETED
Conditions: Chronic Periodontitis|Diabetes Mellitus
Interventions: OTHER: non-surgical periodontal treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Skeletal Class II Malocclusion With Modified Twin-Block Appliance With Clear Plates
Status: RECRUITING
Conditions: Malocclusion, Angle Class II
Interventions: DEVICE: Modified Twin-Block Appliance with Clear Plates.|DEVICE: Traditional Twin-Block appliance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Investigate the Pharmacokinetics and Safety of Cadazolid in Patients With Clostridium Difficile Infection
Status: COMPLETED
Conditions: Clostridium Difficile Infection
Interventions: DRUG: Cadazolid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: IGC-AD1 Trial on Agitation in Dementia Due to Alzheimer's
Status: RECRUITING
Conditions: Alzheimer Disease|Agitation,Psychomotor|Depression|Anxiety|Memory Impairment|Care Giving Burden|NPS|Agitated; State, Acute Reaction to Stress|Aggression|Aggressive Outburst
Interventions: DRUG: Agitation management in Alzheimer's disease (IGC-AD1-Active)|DRUG: Agitation management in Alzheimer's disease (IGC-AD1-Placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Patient-facing Tool to Reduce Opioid-Psychotropic Polypharmacy in People Living With Dementia (PLWD)
Status: COMPLETED
Conditions: Polypharmacy|Dementia
Interventions: BEHAVIORAL: Educational nudge intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of RNA-based Vaccines Against SARS-CoV-2 Variants in Healthy Participants
Status: COMPLETED
Conditions: SARS-CoV2 Infection|COVID-19|SARS-CoV-2 Acute Respiratory Disease|SARS (Disease)
Interventions: BIOLOGICAL: BNT162b2|BIOLOGICAL: BNT162b2 (B.1.1.7 + B.1.617.2)|BIOLOGICAL: BNT162b2 (B.1.1.7)|BIOLOGICAL: BNT162b2 (B.1.617.2)|BIOLOGICAL: BNT162b2 (B.1.1.529.1)|OTHER: Observational
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Intranasal Insulin on Cognitive Processes and Appetite
Status: COMPLETED
Conditions: Obesity
Interventions: DRUG: Intranasal Insulin|DRUG: Intranasal Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Food on the Bioavailability of 15 mg Estetrol/3 mg Drospirenone Tablets in Healthy Female Volunteers
Status: COMPLETED
Conditions: Contraception
Interventions: DRUG: 15 mg E4/3 mg DRSP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: A Phase 1, Multicenter, Open-Label, Dose-Escalation, Safety, Pharmacokinetic, and Pharmacodynamic Study of E6201 in Subjects With Advanced Solid Tumors
Status: COMPLETED
Conditions: Advanced Solid Tumors
Interventions: DRUG: E6201
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT