pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Real Time In-Vivo Body Surface Dosimetry for External Beam Radiation Therapy
Status: COMPLETED
Conditions: Cancer of the Gastrointestinal, Genitourinary or Gynecologic Systems
Interventions: OTHER: Novel nano-scintillatorfiber-optic dosimeter ( nanoFOD)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Repetitive Transcranial Magnetic Stimulation With H-coil in Parkinson's Disease (rTMS-PD)
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: DEVICE: rTMS with H-coil|DEVICE: rTMS with H-coil|DEVICE: rTMS with H-coil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Energetic View on Creativity, Psychopathology and Intelligence: The Brain2Business Study
Status: COMPLETED
Conditions: General Psychopathology|Fatigue|Depressive Disorder, Major
Interventions: BEHAVIORAL: Integrated 5-day Gratitude Exercise and Behavioral Activation Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Oxytocin Effects on Food Motivation Pathways
Status: COMPLETED
Conditions: Overweight and Obesity
Interventions: DRUG: Oxytocin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Assessing the Response Rate of Neo-adjuvant Taxotere and Trastuzumab in Nigerian Women With Breast Cancer
Status: RECRUITING
Conditions: Breast Cancer|Breast Cancer Female|HER2-positive Breast Cancer|Breast Cancer Stage II|Breast Cancer Stage III
Interventions: DRUG: Docetaxel|DRUG: Herceptin|DRUG: FEC|DRUG: Tamoxifen|DRUG: Letrozole|DRUG: LHRH agonist
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Detection of Obstetric Anal Sphincter Injuries With ONIRY Device
Status: COMPLETED
Conditions: Obstetric Anal Sphincter Injury|Delivery Complication|Obstetric Complication
Interventions: DIAGNOSTIC_TEST: Laboratory tests: blood and faeces tests|DIAGNOSTIC_TEST: Gynaecological and proctological examinations|DIAGNOSTIC_TEST: 3-D Endoanal Ultrasound|DEVICE: ONIRY measurement|DIAGNOSTIC_TEST: High-resolution anorectal manometry|DIAGNOSTIC_TEST: ECG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of Crisaborole Ointment 2% in Children Aged 3-24 Months With Mild to Moderate Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: Crisaborole ointment 2%
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Τhe Effectiveness of Hydrotherapy Exercises on the Rehabilitation of Hemiplegic Patients
Status: COMPLETED
Conditions: Hemiplegics
Interventions: PROCEDURE: Hydrokinesiotherapy Intervention|PROCEDURE: Land-based exercise intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: High and Low Laser for Subacromial Impingement Syndrome
Status: COMPLETED
Conditions: Subacromial Impingement Syndrome
Interventions: OTHER: high intensity laser in addition to traditional physical therapy exercises|OTHER: low level laser in addition to traditional physical therapy exercises|OTHER: traditional physical therapy exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study for the Treatment of Non-Aggressive Basal Cell Carcinoma With Photodynamic Therapy
Status: COMPLETED
Conditions: Basal Cell Carcinoma (BCC)
Interventions: DRUG: BF-200 ALA|DRUG: methyl-aminolevulinate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Azacytidine, Bendamustine, Piamprizumab in Refractory/Relapsed B-cell Non-Hodgkin's Lymphoma
Status: UNKNOWN
Conditions: Non-hodgkin Lymphoma,B Cell
Interventions: DRUG: Azacytidine, Bendamustine and Piamprizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Nitric Oxide Administration in Attenuating Ischemia/Reperfusion Injury During Neonatal Cardiopulmonary Bypass
Status: COMPLETED
Conditions: Ischemia/Reperfusion Injury After Neonatal Cardiac Surgery|Inflammatory Reaction After Neonatal Cardiac Surgery
Interventions: DRUG: Inhaled Nitric Oxide|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of 500 mg Immediate Release and Extended Release Methylnaltrexone on Loperamide-induced Delay of the Oro-cecal and Whole-gut Transit Time in Healthy Subjects
Status: COMPLETED
Conditions: Intestinal Obstruction
Interventions: DRUG: Loperamide|DRUG: Loperamide placebo|DRUG: Methylnaltrexone placebo|DRUG: Methylnaltrexone 12 mg sc.|DRUG: Methylnaltrexone IR capsule|DRUG: Methylnaltrexone ER capsule|DEVICE: Colon Transit|DRUG: Sulfasalazine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of DR-0201 in Subjects With Relapsed/Refractory B-Cell Non-Hodgkin Lymphoma
Status: RECRUITING
Conditions: B-cell Non Hodgkin Lymphoma
Interventions: DRUG: DR-0201
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigating Association Between Spine, Scapular, Shoulder and Core in Swimmers
Status: ENROLLING_BY_INVITATION
Conditions: Postural Kyphosis|Postural Lordosis|Movement, Abnormal|Spine Injury|Cervical Lordosis
Interventions: PROCEDURE: Spine Posture Assessment|PROCEDURE: Spine Movement Assessment|PROCEDURE: Core Muscle Endurance Assessment|PROCEDURE: Scapular Dyskinesia|PROCEDURE: Shoulder Strength
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Feasibility Study of Radiofrequency Heating of Cardiac Infarction Scar to Treat Heart Failure
Status: TERMINATED
Conditions: Heart Failure
Interventions: PROCEDURE: Radiofrequency heating of the myocardial infarct scar|PROCEDURE: Coronary Artery Bypass Grafting (CABG) surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Safety and Efficacy of Deucravacitinib Compared to Placebo Hidradenitis Suppurativa (HS).
Status: RECRUITING
Conditions: Hidradenitis Suppurativa
Interventions: DRUG: Deucravacitinib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparative Clinical and Radiographic Study of Collagen Based Pulpotomy Versus Biodentine Pulpotomy in Children With Cariously Exposed Vital Primary Molars
Status: UNKNOWN
Conditions: Carious Exposure of Pulp
Interventions: DRUG: sterile medicated collagen particles, Biofil-AB ,Eucare Pharmaceuticals Pvt. Ltd, Chennai, India|DRUG: Biodentine (Septodont, Saint-Maur-des-Fossés, France)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: EUS-Guided Choledochoduodenostomy Versus ERCP for Primary Biliary Decompression in Distal Malignant Biliary Obstruction
Status: RECRUITING
Conditions: Malignant Biliary Obstruction
Interventions: PROCEDURE: Biliary drainage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Research of Standard Diagnosis and Treatment for HSPN in Children
Status: UNKNOWN
Conditions: Henoch-Schoenlein Purpura Nephritis
Interventions: DRUG: Prednisone|DRUG: Cyclophosphamide(CTX)|DRUG: Mycophenolate mofetil(MMF)|DRUG: Leflunomide(LEF)|DRUG: Angiotensin-converting enzyme inhibitor(ACEI)|DRUG: Methylprednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety and Viability of an E. Coli Nissle Colibactin Knockout in Healthy Volunteers
Status: COMPLETED
Conditions: Diabetes
Interventions: DIETARY_SUPPLEMENT: EcN Colibactin knockout|DIETARY_SUPPLEMENT: E Coli Nissle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of HIPEC as NACT and Postoperative Chemotherapy in the Treatment of Advanced-Stage Epithelial Ovarian Cancer
Status: UNKNOWN
Conditions: Epithelial Ovarian Cancer|Fallopian Tube Cancer|Primary Peritoneal Carcinoma
Interventions: PROCEDURE: Hyperthermic Intraperitoneal Chemotherapy|PROCEDURE: Interval debulking surgery|DRUG: neoadjuvant chemotherapy|DRUG: adjuvant chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: 13-valent Pneumococcal Conjugate Vaccine Study in Adults and Children in India
Status: COMPLETED
Conditions: Prevention of Pneumonia and Invasive Disease Caused by the Serotypes in 13vPnC
Interventions: BIOLOGICAL: 13-valent Pneumococcal conjugate vaccine|PROCEDURE: Blood sample collection
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effect of High Volume Injection With and Without Steroid in Chronic Achilles Tendinopathy
Status: COMPLETED
Conditions: Tendinopathy
Interventions: DRUG: High Volume injection without corticosteroid|DRUG: High Volume injection with corticosteroid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Preventive Mental Health Programme on Social/Emotional Functioning and Resilience in Children in South Africa
Status: NOT_YET_RECRUITING
Conditions: Psychological Well-Being
Interventions: BEHAVIORAL: Mental Health Prevention and Promotion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: FMISO PET/CT Imaging Trial for Assessing Hypoxia in Soft Tissue Sarcomas
Status: TERMINATED
Conditions: Soft Tissue Sarcoma
Interventions: DRUG: 18F-FMISO
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Comparing Efficacy and Safety of Inhaled SNG001 to Placebo
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Interferon beta 1a|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Bosentan in Patients With Metastatic Melanoma Treated With Dacarbazine (DTIC)
Status: COMPLETED
Conditions: Melanoma
Interventions: DRUG: Bosentan|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Geriatric Optimization Plan to Improve Survival in Older Adult Allogeneic Hematopoietic Cell Transplant Candidates, OTIS Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Lymphoblastic Leukemia|Acute Myeloid Leukemia|Aplastic Anemia|Chronic Lymphocytic Leukemia|Chronic Myelogenous Leukemia, BCR-ABL1 Positive|Hematopoietic and Lymphoid Cell Neoplasm|Hodgkin Lymphoma|Myelodysplastic Syndrome|Myelofibrosis|Myeloproliferative Neoplasm|Non-Hodgkin Lymphoma|Plasma Cell Myeloma
Interventions: OTHER: Health Promotion and Education|OTHER: Medical Device Usage and Evaluation|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of the Safety of R256918 in Obese Patients
Status: COMPLETED
Conditions: Obesity|Nutritional and Metabolic Diseases|Metabolic Diseases|Nutrition Disorders|Overweight
Interventions: DRUG: R256918|DRUG: placebo|DRUG: R256918
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prescription-based Fluid Management Versus Usual Care in Critically Ill Patients on KRT Trial in UK
Status: NOT_YET_RECRUITING
Conditions: Acute Renal Failure on Dialysis (Disorder)
Interventions: PROCEDURE: Fluid removal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Influence of Deep Brain Stimulation on the Spinal Deformities Associated With Parkinson's Disease
Status: UNKNOWN
Conditions: Parkinson Disease|Spine Degeneration|Spine Deformity|Spinal Disease
Interventions: PROCEDURE: Deep Brain Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Early Phase Achilles Tendinopathy - the Effect of NSAIDs
Status: COMPLETED
Conditions: Tendon Injuries|Achilles Tendinopathy|Inflammation
Interventions: DRUG: Naproxen 500 Mg|DRUG: Placebo Oral Tablet|OTHER: Heavy resistance training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety and Tolerability of Combined Treatment With Nilotinib and Ruxolitinib in CML and Ph+ ALL Patients
Status: COMPLETED
Conditions: Chronic Myeloid Leukemia
Interventions: DRUG: Nilotinib|DRUG: Ruxolitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Pneumocystis in COPD (the TOPIC Study)
Status: TERMINATED
Conditions: COPD Exacerbation Acute
Interventions: DRUG: Trimethoprim Sulfamethoxazole|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Associations of Exposure to Phthalates With Insulin Resistance and Epigenetic Change
Status: UNKNOWN
Conditions: Insulin Resistance|Decreased Pulmonary Function
Interventions: OTHER: non- PVC containing packing materials|OTHER: PVC containing packing materials
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Clostridioides Difficile Colonisation
Status: RECRUITING
Conditions: Clostridioides Difficile Infection
Interventions: BIOLOGICAL: 10E4 NTCD spores|BIOLOGICAL: 10E7 NTCD spores|OTHER: placebo|DRUG: Vancomycin Oral Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: DM-BOOST Para Latinx: a Diabetes Mellitus Program Using Behavioral Economics to Optimize Outreach and Self-management Support With Technology for Latinx Patients
Status: NOT_YET_RECRUITING
Conditions: Diabetes Mellitus, Type 2
Interventions: BEHAVIORAL: Diabetes BOOST|BEHAVIORAL: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: DME And VEGF Trap-Eye [Intravitreal Aflibercept Injection (IAI;EYLEA®;BAY86-5321)] INvestigation of Clinical Impact
Status: COMPLETED
Conditions: Diabetic Macular Edema
Interventions: PROCEDURE: Laser Photocoagulation|DRUG: Intravitreal Aflibercept Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Adjuvant ctDNA-Adapted Personalized Treatment in Early Stage NSCLC (ADAPT-E)
Status: RECRUITING
Conditions: Non-small Cell Lung Cancer|Non-small Cell Lung Cancer Stage I|Non-small Cell Lung Cancer Stage II|Non-small Cell Lung Cancer Stage III
Interventions: DEVICE: AVENIO ctDNA Surveillance Kit|DRUG: Durvalumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transcricoid Injection vs. Spray as You go Method for Local Anaesthesia During Bronchoscopy
Status: COMPLETED
Conditions: Pulmonary Disease
Interventions: DRUG: Transcricoid injection|DRUG: Spray as you go
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Etoricoxib Versus Ibuprofen in Third Molar Extraction Pain
Status: UNKNOWN
Conditions: Dental Extraction
Interventions: DRUG: etoricoxib|DRUG: ibuprofen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Critical Time Intervention-Peer Support
Status: RECRUITING
Conditions: Psychotic Disorders|Schizophrenia|Bipolar Disorder|Schizo Affective Disorder
Interventions: BEHAVIORAL: Critical Time Intervention - Peer Support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating the 2-dose Immunization Schedule of Human Papillomavirus (HPV)-16/18 in Adolescent Females
Status: COMPLETED
Conditions: Human Papillomavirus|Cervical Intraepithelial Neoplasia|Persistent Infection
Interventions: BIOLOGICAL: HPV-16/18 vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparison of Intubation With Nerve Block and With Sedation in Awake Patients
Status: UNKNOWN
Conditions: Intubation Complication
Interventions: DRUG: Nerve block with Lidocain|DRUG: Fentanyl|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Epinephrine Inhalation Aerosol USP, a HFA-MDI Study for Assessment of Pharmacokinetics
Status: COMPLETED
Conditions: Asthma|Bronchospasm|Wheezing|Shortness of Breath
Interventions: DRUG: Epinephrine Inhalation Aerosol, HFA|DRUG: Epinephrine Inhalation Aerosol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Quilting Sutures on Post-operative Drainage After Mastectomy and/or Axillary Lymph Node Dissection
Status: TERMINATED
Conditions: Breast Cancer Female
Interventions: PROCEDURE: quilting|PROCEDURE: conventional suture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating Etanercept in Patients With Rheumatoid Arthritis(RA), Juvenile Idiopathic Arthritis (JIA), or Psoriatic Arthritis (PsA) in Spain
Status: COMPLETED
Conditions: Arthritis, Psoriatic|Arthritis, Rheumatoid
Interventions: DRUG: Etanercept
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Teneligliptin Versus Linagliptin in Diabetes Mellitus Type Two Patients
Status: COMPLETED
Conditions: Type2 Diabetes Mellitus
Interventions: DRUG: Teneligliptin|DRUG: Linagliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cardiac Resynchronization in Atrial Fibrillation Trial - a Pilot Study
Status: UNKNOWN
Conditions: Atrial Fibrillation|Heart Failure
Interventions: DRUG: Amiodarone|PROCEDURE: External electrical cardioversion (EEC)|DRUG: Pharmacotherapy to slow and control ventricular rate|PROCEDURE: Atrioventricular junction ablation (AVJA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nutritional Support and Prophylaxis Doses of Azithromycin for Pregnant Women - Mumta Pregnant Women Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Undernutrition
Interventions: DIETARY_SUPPLEMENT: Balanced-energy protein (BEP)|DRUG: Azithromycin Tablets|DRUG: Choline Bitartrate|DRUG: Nicotinamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Comparing Two Vitamin D Supplements for Infants: Liquid Versus D-Strips
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Vitamin D, cholecalciferol|DIETARY_SUPPLEMENT: Vitamin D, cholecalciferol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Evaluation of Fenugreek Seed Extract In Type- 2 Diabetes: An Add-On Study
Status: COMPLETED
Conditions: Diabetes
Interventions: DIETARY_SUPPLEMENT: Fenugreek seeds extract|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety, Tolerability and Efficacy of Single Dose Low Cost Minipool Intravenous Immunoglobulins in Moderately Severe Newly Diagnosed ITP
Status: UNKNOWN
Conditions: Newly Diagnosed Pediatric ITP
Interventions: DRUG: IVIG prepared by minipool technology|DRUG: standard IVIG product
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Carriere® Motion™ Appliance on Airway Dimensions
Status: COMPLETED
Conditions: Effect of Carriere® Motion™ Appliance on Pharyngeal Airway Dimensions|Effect of Carriere® Motion™ Appliance on Skeletal and Dental Measurements
Interventions: DEVICE: Carriere® Motion™ Appliance
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antiplatelet Therapy After Successful Percutaneous Coronary Intervention for Chronically Occluded Coronary Artery
Status: NOT_YET_RECRUITING
Conditions: Chronic Total Occlusion
Interventions: PROCEDURE: Percutaneous coronary intervention|DRUG: Short dual Aspirin/Clopidogrel therapy|OTHER: Long dual Aspirin/Clopidogrel therapy|OTHER: Follow-up visit at 1 month|OTHER: Follow-up visit at 6 months|OTHER: Follow-up visit at 12 months
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Subjective and Objective Performance of Systane Complete Multi-Dose PF Versus Walgreen's Lubricant Balance
Status: COMPLETED
Conditions: Dry Eye
Interventions: DRUG: Systane Complete Multi-Dose PF|DRUG: Walgreen's Lubricant Balance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PADN to Treat Severe Obstructive Sleep Apnea
Status: TERMINATED
Conditions: Obstructive Sleep Apnea Syndrome
Interventions: PROCEDURE: Pulmonary Arterial Denervation|PROCEDURE: Sham procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Multi-professional Care Pathway and Network for the Promotion of Needs-oriented, Resident-oriented Exercise Therapy for Oncological Patients
Status: ENROLLING_BY_INVITATION
Conditions: Cancer|Exercise|Implementation
Interventions: BEHAVIORAL: Exercise oncology counseling and referal
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Chloroquine in Combination With VELCADE and Cyclophosphamide for Relapsed and Refractory Multiple Myeloma
Status: TERMINATED
Conditions: Multiple Myeloma
Interventions: DRUG: Velcade|DRUG: Cyclophosphamide|DRUG: Chloroquine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Promoting Safety Behaviours in Antenatal Care Using a Video
Status: COMPLETED
Conditions: Intimate Partner Violence
Interventions: BEHAVIORAL: Safety behaviour promoting video|BEHAVIORAL: Control video
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Test Whether Different Doses of BI 456906 Help People With Overweight or Obesity to Lose Weight
Status: COMPLETED
Conditions: Obesity
Interventions: DRUG: BI 456906|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Tab.Labetalol and Tab.Nifedipine for Management of Postpartum Hypertension
Status: UNKNOWN
Conditions: Postnatal Hypertension
Interventions: DRUG: Labetalol|DRUG: Nifedipine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: RAVE: Radial Artery Vascular Complication and Resource Utilization
Status: COMPLETED
Conditions: Angiogram|Percutaneous Coronary Intervention
Interventions: DEVICE: RadAR EasyCLik plus ®-STF hemostatic pad|DEVICE: TR BAND® Compression device plus ®-STF hemostatic pad|DEVICE: SoftSeal®-STF hemostatic pad|DEVICE: VascBand™ Hemostat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Broccoli, Peas and PIN
Status: COMPLETED
Conditions: Prostatic Intraepithelial Neoplasia
Interventions: DIETARY_SUPPLEMENT: Broccoli|DIETARY_SUPPLEMENT: Peas
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Survey and Cognitive Behavior Therapy for Chronic Fatigue Syndrome/Myalgic Encephalomyelitis
Status: COMPLETED
Conditions: Chronic Fatigue Syndrome|Myalgic Encephalomyelitis|Fatigue|Pain
Interventions: BEHAVIORAL: CBT|BEHAVIORAL: CBT|BEHAVIORAL: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Controlled Trial of Growth Hormone in Phelan-McDermid Syndrome and Idiopathic Autism
Status: ENROLLING_BY_INVITATION
Conditions: Phelan-McDermid Syndrome|Autism Spectrum Disorder (ASD)
Interventions: DRUG: Growth Hormone|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vaccine Therapy in Treating Patients With Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: BIOLOGICAL: GP2 peptide + GM-CSF vaccine|BIOLOGICAL: GM-CSF (sargramostim)|BIOLOGICAL: AE37 + GM-CSF vaccine|BIOLOGICAL: GM-CSF (sargramostim)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Metformin and Diane-35 on PCOS Patients,a Randomized, Controlled, Prospective Clinical Trial
Status: COMPLETED
Conditions: Polycystic Ovary Syndrome|Insulin Resistance
Interventions: DRUG: Metformin|DRUG: Ethinylestradiol and Cyproterone Acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vitamin B12 vs B3 for Nerve Regeneration and Functional Recovery After Pediatric Traumatic Brain Injury
Status: COMPLETED
Conditions: Traumatic Brain Injury
Interventions: DRUG: Vitamin B3|DRUG: Vitamin B12
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study With GFT505 (80mg) in Patients With Insulin Resistance and Abdominal Obesity
Status: COMPLETED
Conditions: Insulin Resistance|Abdominal Obesity
Interventions: DRUG: GFT505 80mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Bioequivalence of 12 mg Paliperidone Extended Release Tablets Manufactured at Gurabo and Vacaville
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Paliperidone ER
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study for the Use of TKIs for Treatment of Cognitive Decline Due to Degenerative Dementias
Status: ENROLLING_BY_INVITATION
Conditions: Mild Cognitive Impairment|Dementia
Interventions: DRUG: bosutinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Donor Dendritic Cells And Donor Lymphocytes in Patients With Relapsed Hematologic Malignancies After Allogeneic Transplant
Status: COMPLETED
Conditions: Hematologic Malignancy
Interventions: BIOLOGICAL: Infusion of donor dendritic cells|BIOLOGICAL: Infusion of donor lymphocytes
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A 12-week Study To Evaluate PF-06291874 Once a Day in Adults With T2DM Inadequately Controlled On Metformin
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: PF-06291874|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Motor Function Efficacy of Pharmacological Treatments Targeting Energy Metabolism, in Parkinson's Patients
Status: NOT_YET_RECRUITING
Conditions: Parkinson Disease|Gait Analysis|Therapy, Directly Observed|Metabolic Disease
Interventions: DRUG: Terazosin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Optimizing Pulsatility During Cardiopulmonary Bypass to Reduce Acute Kidney Injury
Status: NOT_YET_RECRUITING
Conditions: Acute Kidney Injury|Hemolysis|Thrombocytopenia|Surgery
Interventions: OTHER: Non-pulsatile blood flow|OTHER: Pulsatile blood flow
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A RCT to Compare OHRQoL Outcome for SLB and CB
Status: UNKNOWN
Conditions: Malocclusion
Interventions: DEVICE: Self-ligating brackets (SLB)|DEVICE: Conventional brackets (CB)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility of HOBSCOTCH Telehealth Intervention in Refractory Epilepsy
Status: UNKNOWN
Conditions: Refractory Epilepsy
Interventions: BEHAVIORAL: HOBSCOTCH: "Home-Based Self-Management and Cognitive Training Changes Lives"
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phenytoin Cream for the Treatment of Neuropathic Pain
Status: COMPLETED
Conditions: Chronic Idiopathic Axonal Polyneuropathy
Interventions: DRUG: phenytoin cream|OTHER: Placebo cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: LIFT Study: A Safety, Tolerability, Efficacy, and Pharmacokinetics Study of TERN-101 in Subjects With Non-Cirrhotic Non-Alcoholic Steatohepatitis (NASH)
Status: COMPLETED
Conditions: NASH - Nonalcoholic Steatohepatitis
Interventions: DRUG: TERN-101|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Nanatinostat Plus Valganciclovir in Patients With Advanced EBV+ Solid Tumors, and in Combination With Pembrolizumab in EBV+ RM-NPC
Status: RECRUITING
Conditions: Nasopharyngeal Carcinoma|EBV-Related Gastric Carcinoma|EBV-Related Leiomyosarcoma|EBV Related Carcinoma|EBV-Related Sarcoma
Interventions: DRUG: Nanatinostat|DRUG: Nanatinostat|DRUG: Valganciclovir|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Dose Finding Study of New Vehicle Formulations Containing Ingenol Mebutate to Treat Actinic Keratosis on the Forearm
Status: COMPLETED
Conditions: Actinic Keratosis
Interventions: DRUG: once daily for two consecutive days (Picato)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Trajectory of Psychological Distress Among Infertility Women
Status: RECRUITING
Conditions: Infertility|Heart Rate Variability|Biofeedback
Interventions: BEHAVIORAL: Web-based mind-body intervention with HRVB|BEHAVIORAL: Web-based mind-body intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Single Dose Study In Japanese And Western Healthy Subjects To Investigate The Safety, Tolerability And Pharmacokinetics Of PF-04991532
Status: COMPLETED
Conditions: Diabetes Mellitus|Diabetes Mellitus, Type 2|Glucose Metabolism Disorders
Interventions: DRUG: PF-04991532|DRUG: Placebo|DRUG: PF-04991532
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: The Effect of Byetta and Symlin on Post-meal Meal Blood Sugar Levels in Children With Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: Byetta (exenatide)|DRUG: Symlin (pramlintide)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: KF2019#1-trial: Effects of a Thrombocyte Inhibitor on a Cholesterol-lowering Drug
Status: UNKNOWN
Conditions: Pharmacokinetics
Interventions: DRUG: Placebo|DRUG: Ticagrelor|DRUG: Rosuvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of Biodegradable & Metal Plates for Fixing Ankle Fracture
Status: UNKNOWN
Conditions: Distal Fibular Fracture|Bimalleolar Fracture|Trimalleolar Fracture
Interventions: DEVICE: biodegradable fixation system (Inion OTPS FreedomPlateTM)
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Digital Intervention Promoting Physical Activity Among Obese People (DIPPAO)
Status: COMPLETED
Conditions: Obesity|Diabete Type 2
Interventions: DEVICE: Kiplin|BEHAVIORAL: face-to-face
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: High-flow Nasal Cannula Oxygen Versus Conventional Oxygen Therapy After Pulmonary Lobectomy
Status: COMPLETED
Conditions: Respiratory Insufficiency|Lung Cancer
Interventions: DEVICE: High-flow Nasal Cannula Oxygen (HFNCO)|DEVICE: Conventional oxygen treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Safety and Efficacy of Zanubrutinib in Refractory/Relapsed Autoimmune Hemolytic Anemia
Status: RECRUITING
Conditions: Refractory/Relapsed Autoimmune Hemolytic Anemia
Interventions: DRUG: Zanubrutinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BCAA vs. Rifaximin in Patients With Cirrhosis for Secondary Prophylaxis of HE
Status: NOT_YET_RECRUITING
Conditions: Hepatic Encephalopathy|Decompensated Cirrhosis|Minimal Hepatic Encephalopathy
Interventions: DRUG: Oral Branched chain Amino acid|DRUG: Rifaximin 550 MG|DRUG: Lactulose|DRUG: Placebo for BCAA|DRUG: Placebo for Rifaximin 550mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Pertuzumab and Trastuzumab Subcutaneous (SC) Treatment in Combination With a Taxane in Participants With Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Docetaxel|DRUG: Nab-paclitaxel|DRUG: Paclitaxel|DRUG: Pertuzumab|DRUG: Trastuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Zolmitriptan Nasal Spray Versus Eletriptan in the Acute Treatment of Migraine
Status: COMPLETED
Conditions: Acute Migraine|Migraine Headache|Headache Disorders
Interventions: DRUG: Zolmitriptan 5 mg Nasal Spray|DRUG: Eletriptan 40 mg tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Binaural Sound for Remimazolam Induction
Status: RECRUITING
Conditions: General Anesthesia|Prostate Cancer|Uterine Myoma
Interventions: PROCEDURE: Binaural sound|PROCEDURE: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pharmacokinetic Interaction Between BIA 9-1067 and Standard-release Levodopa/Carbidopa
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: DRUG: BIA 9-1067|DRUG: Sinemet® 100/25 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: COlchicine iN Circulating Inflammatory Markers After StrokE (CONCISE)
Status: NOT_YET_RECRUITING
Conditions: Ischemic Stroke|Atherosclerosis
Interventions: DRUG: Colchicine 0.5 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety and Efficacy of AM3101 to Augment Meniscal Healing
Status: RECRUITING
Conditions: Meniscus Tear
Interventions: DRUG: AM3101|DRUG: Saline Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Estimation of the Dietary Requirement for Vitamin D in Ethnic Groups
Status: RECRUITING
Conditions: Vitamin D Deficiency|Immune Health|Muscle Function
Interventions: DIETARY_SUPPLEMENT: Vitamin D Supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Why do Oral Contraceptives Prevent Ovarian Cancer?
Status: COMPLETED
Conditions: Ovarian Cancer Risk|Risk-reducing Surgery|Fallopian Tube Fimbriae|Ovarian Cortical Inclusion Cysts
Interventions: DRUG: OrthoNovum 1/35
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Ivabradine in Hemodialysed Patients With Increased Heart Rate
Status: UNKNOWN
Conditions: High Heart Rate
Interventions: DRUG: Ivabradine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Irinotecan and 3-AP in Treating Patients With Metastatic or Unresectable Solid Tumors
Status: COMPLETED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: triapine|DRUG: irinotecan hydrochloride|OTHER: laboratory biomarker analysis|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 1/2a Dose-Escalation Study of CRLX301 in Patients With Advanced Solid Tumors
Status: TERMINATED
Conditions: Advanced Solid Tumor Malignancy
Interventions: DRUG: CRLX301
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of the Pharmacokinetics and Safety of ANT3310 Combined With Meropenem in Renally Impaired Subjects
Status: RECRUITING
Conditions: Renal Impairment
Interventions: DRUG: ANT3310|DRUG: Meropenem
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Phase I/II Study of Oral S-1 Plus Gemcitabine in Patients With Metastatic Pancreatic Cancer
Status: SUSPENDED
Conditions: Pancreatic Cancer
Interventions: DRUG: Gemcitabine|DRUG: S-1
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Armodafinil (CEP-10953) in the Treatment of Excessive Sleepiness Associated With Narcolepsy
Status: COMPLETED
Conditions: Narcolepsy
Interventions: DRUG: Armodafinil|DRUG: Armodafinil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Effects of Dapagliflozin on Central Hemodynamics and Urine Albumin Excretion in Patients With Type 2 Diabetes.
Status: TERMINATED
Conditions: Diabetes Mellitus
Interventions: DRUG: Dapagliflozin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dynamics of the Immune Responses to Repeat Influenza Vaccination Exposures
Status: ACTIVE_NOT_RECRUITING
Conditions: Influenza, Human
Interventions: BIOLOGICAL: FluBlok|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effectiveness of a Self-guided Mobile Application in Improving Obsessive Compulsive Disorder Symptoms
Status: ACTIVE_NOT_RECRUITING
Conditions: Obsessive-Compulsive Disorder
Interventions: DEVICE: Self-guided program on obsessive compulsive disorder|DEVICE: Self-guided program on cooperation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: PK/PD Study of Anti-Infective Drugs in Critically Ill Patients Receiving Extracorporeal Membrane Oxygenation Treatment
Status: NOT_YET_RECRUITING
Conditions: Critical Illness|Extracorporeal Membrane Oxygenation Complication
Interventions: DEVICE: ECMO treatment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Influenza Vaccination on the Systemic Inflammatory Response and Myocardial Protection in Patients Undergoing Cardiac Surgery: a Randomized Controlled Trial
Status: COMPLETED
Conditions: Systemic Inflammatory Response
Interventions: BIOLOGICAL: Influenza Vaccine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Comparison of Ultrasound Guided Erector Spinae Plane Block and Ultrasound Guided Pericapsular Nerve Group Block for Pediatric Hip Surgery
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: PROCEDURE: erector spinae plane block|PROCEDURE: pericapsular nerve group block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Enhanced Versus Standard Blood Pressure Lowering on Intracranial Aneurysm Rupture or Growth China Antihypertensive Trial for Intracranial Aneurysm (ChATIA-1)
Status: RECRUITING
Conditions: Unruptured Intracranial Aneurysm
Interventions: OTHER: blood pressure lowering
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Screening and Intervention for Subclinical Coronary Artery Disease in Patients With Type 2 Diabetes
Status: RECRUITING
Conditions: Type 2 Diabetes|Cardiovascular Diseases
Interventions: OTHER: CAC-based treatment strategy|OTHER: Standard treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Optimization of Perioperative Analgesia Protocol for Uniportal Video-assisted Thoracoscopic Surgery
Status: RECRUITING
Conditions: Uniportal Video-assisted Thoracic Surgery
Interventions: PROCEDURE: Ultrasound-guided paraspinal block and patient-controlled intravenous analgesia pump|PROCEDURE: Ultrasound-guided erector spinal block and patient-controlled intravenous analgesia pump|PROCEDURE: Patient-controlled intravenous analgesia pump
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study Of SU011248 In Combination With Docetaxel In Patients With Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Neoplasms
Interventions: DRUG: Sunitinib (Sutent)|DRUG: Taxotere
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT