pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Improving Post Discharge Care After Acute Kidney Injury
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Kidney Injury
Interventions: OTHER: Risk guided follow-up|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Canady Helios Cold Plasma Scalpel Treatment at the Surgical Margin and Macroscopic Tumor Sites
Status: UNKNOWN
Conditions: Recurrent Malignant Solid Neoplasm|Stage IV Breast Cancer|Stage IV Prostate Cancer|Stage IV Pancreatic Cancer|Stage IV Non-small Cell Lung Cancer|Stage IV Ovarian Cancer|Stage IV Fallopian Tube Cancer|Stage IV Colon Cancer|Stage IV Colorectal Cancer|Stage IV Liver Cancer|Stage IV Renal Cell Cancer|Stage IV Rectal Cancer|Stage IV Lung Cancer|Stage IV Small Intestinal Cancer|Stage IV Gastric Cancer|Stage IV Bladder Cancer
Interventions: DEVICE: Canady Helios Cold Plasma Scalpel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Citalopram Versus Citalopram Plus Pindolol in Major Depressive Disorder
Status: COMPLETED
Conditions: Major Depressive Disorder|Antidepressant Treatment Response
Interventions: DRUG: Pindolol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Standard Chemotherapy With of Without Axitinib in Malignant Mesothelioma
Status: COMPLETED
Conditions: Malignant Pleural Mesothelioma
Interventions: BIOLOGICAL: axitinib|DRUG: chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Autologous SVF Cells in Treating Patients With Osteoarthritis
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: BIOLOGICAL: autologous SVF|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Lenalidomide and Obinutuzumab in Treating Patients With Recurrent or Refractory Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma
Status: TERMINATED
Conditions: Recurrent Chronic Lymphocytic Leukemia|Recurrent Small Lymphocytic Lymphoma|Refractory Chronic Lymphocytic Leukemia|Refractory Small Lymphocytic Lymphoma
Interventions: DRUG: Lenalidomide|BIOLOGICAL: Obinutuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Myopia:the Role of Cone Opsin Mutations & Glasses That Control Axial Elongation
Status: WITHDRAWN
Conditions: Myopia
Interventions: OTHER: Spectacles with red-blocking tint|OTHER: Spectacles with holographic diffuser and color neutral tint|OTHER: Spectacles with holographic diffuser and red-blocking tint|OTHER: Spectacles with color neutral tint
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Sonographic QUantification of Venous Circulation In the Preterm Brain
Status: COMPLETED
Conditions: Prematurity; Extreme|Cerebral Circulatory Failure|Intraventricular Hemorrhage|Periventricular Leukomalacia
Interventions: DIAGNOSTIC_TEST: Doppler Ultrasound of venous cerebral circulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Lu177-EB-PSMA617 Radionuclide Treatment in Patients With Metastatic Castration-resistant Prostate Cancer
Status: UNKNOWN
Conditions: Metastatic Castration-resistant Prostate Cancer
Interventions: DRUG: 1.11GBq of 177Lu-EB-PSMA-617|DRUG: 2.00 GBq of 177Lu-EB-PSMA-617|DRUG: 3.70GBq of 177Lu-EB-PSMA-617
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of the Effect of Rectus Muscle Reapproximation Versus Non Reapproximation During CS on Postoperative Pain
Status: UNKNOWN
Conditions: Postoperative Pain
Interventions: PROCEDURE: Rectus muscle reapproximation during CS|PROCEDURE: Rectus muscle non reapproximation during CS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of SPH3127 Tablets on Treating the Diabetic Kidney Disease
Status: RECRUITING
Conditions: Diabetic Kidney Disease
Interventions: DRUG: SPH3127+SPH3127matching placebo+valsartan matching placebo|DRUG: SPH3127+SPH3127matching placebo+valsartan matching placebo|DRUG: SPH3127+valsartan matching placebo|DRUG: SPH3127 matching placebo+valsartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: COVID-19 Breakthrough Infection in Fully Vaccinated People and in People Who Received a Booster Dose
Status: COMPLETED
Conditions: COVID-19 Pneumonia|COVID-19
Interventions: BIOLOGICAL: Pfizer COVID-19 mRNA vaccine|BIOLOGICAL: Moderna COVID-19 mRNA vaccine
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Arterolane-piperaquine Versus Arterolane-piperaquine+Mefloquine Versus Artemether-lumefantrine in Kenyan Children
Status: COMPLETED
Conditions: Plasmodium Falciparum
Interventions: DRUG: Arterolane-piperaquine|DRUG: Arterolane-piperaquine+mefloquine|DRUG: Artemether-lumefantrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigation of Two Newly Developed 2-piece Convex Baseplates in Subjects With Ileostomy
Status: COMPLETED
Conditions: Stoma - Ileostomy
Interventions: DEVICE: Coloplast Test product Y|DEVICE: Coloplast Test product Z
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Immunogenicity and Safety of a Cell-derived Influenza Vaccine in Elderly
Status: COMPLETED
Conditions: Influenza Vaccines
Interventions: BIOLOGICAL: Influenza Vaccine|BIOLOGICAL: Influenza Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Roxadustat (FG-4592) to Correct Anemia in Newly Initiated Dialysis Participants Not on Erythropoiesis-Stimulating Agent Treatment
Status: COMPLETED
Conditions: Dialysis|Anemia
Interventions: DRUG: Roxadustat|DRUG: Oral Iron|DRUG: IV Iron
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Maternal ExeRcIse Timing to Optimise Postprandial Glucose in Type 1 Diabetes
Status: RECRUITING
Conditions: Pregnancy in Diabetic|Type 1 Diabetes
Interventions: OTHER: Exercise and meal testing (acute stimuli)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phase 4 Trial to Evaluate the Efficacy and Safety of Sancuso Patch in Chemotherapy-induced Nausea and Vomiting Associated With the Administration of Highly Emetogenic Chemotherapy (HEC)
Status: COMPLETED
Conditions: Chemotherapy-induced Acute or Delayed Nausea and Vomiting (CINV)
Interventions: DRUG: Sancuso patch|DRUG: Zofran inj.+Zofran tab.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect Of An Anesthetic Procedure On Post Operative Pain Management In Carpal Tunnel Release
Status: COMPLETED
Conditions: Pain, Postoperative|Carpal Tunnel Syndrome
Interventions: DRUG: 10cc injection of bupivacaine|DRUG: 20cc injection of bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Daclatasvir (BMS-790052) Plus Standard of Care in Japanese Patients (Pegylated-interferon Alpha-2a and Ribavirin)
Status: COMPLETED
Conditions: Hepatitis C Infection
Interventions: DRUG: Daclatasvir|DRUG: Daclatasvir|DRUG: Placebo|DRUG: Peginterferon alfa-2a|DRUG: Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: In-person vs. Virtual Delivery of a Group-based Prevention of Postpartum Depression
Status: RECRUITING
Conditions: Postpartum Depression
Interventions: BEHAVIORAL: ROSE Program: In Person|BEHAVIORAL: ROSE Program: Virtual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of Tocilizumab + DMARDs in Patients With Moderate to Severe Active Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: tocilizumab [RoActemra/Actemra]|DRUG: Standard DMARDs (Disease Modifying Anti Rheumatic Drugs)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High Versus Low Dose Serratus Anterior Plane Block After Minimally Invasive Valve Surgery.
Status: RECRUITING
Conditions: Analgesia|Surgery|Cardiac Disease|Post Operative Pain
Interventions: PROCEDURE: High dose serratus anterior plane block (2.4 mg/kg patient ideal body weight)|PROCEDURE: Low dose serratus anterior plane block (1.2mg/kg patient ideal body weight)|DRUG: PCIA with morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study Comparing the Analgesic Efficacy of IV Ibuprofen and IV Ketorolac
Status: UNKNOWN
Conditions: Chronic Pelvic Pain
Interventions: DRUG: IV Ibuprofen|DRUG: IV Ketorolac
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Efficacy of Adalimumab (Humira) for Hidradenitis Suppurativa (HS) Peri-Surgically
Status: COMPLETED
Conditions: Hidradenitis Suppurativa (HS)
Interventions: DRUG: Placebo|DRUG: Adalimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Physical Activity in Patients With Metastatic Colorectal Cancer Who Receive Palliative First-line Chemotherapy
Status: TERMINATED
Conditions: Metastatic Colorectal Cancer
Interventions: OTHER: standard therapy + physical activity program|OTHER: standard therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Negative Symptoms of Schizophrenia With Transcranial Magnetic Stimulation (TMS)
Status: TERMINATED
Conditions: Schizophrenia|Schizoaffective Disorder
Interventions: DEVICE: Transcranial Magnetic Stimulation (TMS)|DEVICE: Transcranial Magnetic Stimulation (TMS)|DEVICE: Transcranial Magnetic Stimulation (TMS)|DEVICE: repetitive transcranial magnetic stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pre-operative Enoxaparin in the Surgical Management of Multi-trauma Patients Undergoing Orthopedic Surgical Procedures
Status: TERMINATED
Conditions: Venous Thrombosis Deep (Limbs)|Surgical Blood Loss
Interventions: DRUG: Enoxaparin Injectable Product|DRUG: Sodium chloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Irradiation Stent Placement Plus TACE for HCC and PVTT
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma|Portal Vein Tumor Thrombosis
Interventions: PROCEDURE: Portal irradiation stent placement|PROCEDURE: TACE|DRUG: Sorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect Study of Tigecycline to Treat Severe Sepsis and Septic Shock
Status: UNKNOWN
Conditions: Abdominal Infection
Interventions: DRUG: glycopeptide plus carbapenem|DRUG: Haizheng Li Xing ® plus tazocin ®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Connecting Breast Cancer Survivors for Exercise
Status: COMPLETED
Conditions: Breast Cancer|Breast Neoplasms
Interventions: BEHAVIORAL: Exercise Counselling|BEHAVIORAL: Partner Matching|BEHAVIORAL: Resistance training sessions led by a QEP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Utility of Some Novel Biomarkers of Patients With Chronic Heart Failure
Status: RECRUITING
Conditions: Heart Failure
Interventions: DIAGNOSTIC_TEST: New york Heart Association Class II-IV|DIAGNOSTIC_TEST: New york Heart Association Class I
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Food Effect Study to Evaluate the Effect of High-Fat Meal on the Relative Bioavailability of PF-07321332 Boosted With Ritonavir in Healthy Adult Participants
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DRUG: PF-07321332/ritonavir|DRUG: Ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Cladribine Tablets: Collaborative Study to Evaluate Impact On Central Nervous System Biomarkers in Multiple Sclerosis
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Sclerosis|Multiple Sclerosis, Relapsing-Remitting
Interventions: DRUG: Cladribine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: An Evaluation of Blood Glucose Levels and Insulin Requirement After Subacromial Corticosteroid Injection in Insulin Dependent Diabetics
Status: WITHDRAWN
Conditions: Shoulder Injury|Insulin-dependent Diabetics
Interventions: DRUG: Dexamethasone|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I-II Study of Vorinostat, Paclitaxel, and Bevacizumab in Metastatic Breast Cancer
Status: COMPLETED
Conditions: Male Breast Cancer|Stage IIIB Breast Cancer|Stage IIIC Breast Cancer|Stage IV Breast Cancer
Interventions: DRUG: vorinostat|DRUG: paclitaxel|BIOLOGICAL: bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 2-part Study to Assess Safety, Pharmacokinetics & Pharmacodynamics of CC-220 & Effect of Food on CC-220 in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: CC-220 0.03 mg|DRUG: CC-220 0.1 mg|DRUG: CC-220 0.3 mg|DRUG: CC-220 1 mg|DRUG: CC-220 2 mg|DRUG: Placebo|DRUG: CC-220|DRUG: CC-220|DRUG: CC-220
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Prospective Evaluation of a Program for Early Identification of Needs and Multidisciplinary Intervention in Supportive Care in Digestive Oncology
Status: COMPLETED
Conditions: Non-colorectal Cancer (Esophagus, Stomach, Liver/Bile Ducts, Pancreas, Neuroendocrine Carcinoma)|Colorectal With Associated Risk Factors
Interventions: OTHER: multidisciplinary assessment and intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Avoid DeliVering TherApies for Non-sustained Arrhythmias in ICD PatiEnts III
Status: COMPLETED
Conditions: Heart Disease
Interventions: DEVICE: Implantable Defibrillator|DEVICE: Implantable Defibrillator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Combination of Fenofibrate and 20 mg Simvastatin Versus 40 mg Simvastatin Monotherapy
Status: COMPLETED
Conditions: Hyperlipidemia
Interventions: DRUG: Fenofibrate/Simvastatin|DRUG: Fenofibrate/Simvastatin|DRUG: Simvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lamivudine in Combination With Chemoimmunotherapy for the Treatment of Extensive Stage Small Cell Lung Cancer
Status: RECRUITING
Conditions: Extensive Stage Lung Small Cell Carcinoma
Interventions: BIOLOGICAL: Atezolizumab|DRUG: Carboplatin|DRUG: Etoposide|DRUG: Lamivudine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Herbal Supplements on Endurance Exercise Performance
Status: COMPLETED
Conditions: Exercise Performance
Interventions: DIETARY_SUPPLEMENT: Placebo of calcium|DIETARY_SUPPLEMENT: Rhodiola|DIETARY_SUPPLEMENT: Rhodiola and Cordyceps
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of Pegasys Monotherapy in Patients With Chronic Hepatitis B Who Have Participated in Previous Studies
Status: COMPLETED
Conditions: Hepatitis B, Chronic
Interventions: DRUG: peginterferon alfa-2a [Pegasys]
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Modular Multi-Basket Trial to Improve Personalized Medicine in Cancer Patients (Basket of Baskets)
Status: RECRUITING
Conditions: Advanced Solid Tumor
Interventions: DRUG: Atezolizumab|DRUG: Futibatinib|DRUG: Amivantamab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Perioperative Bronchodilator in COPD Patients Undergoing Lung Cancer Surgery
Status: UNKNOWN
Conditions: Chronic Obstructive Pulmonary Disease|Non Small Cell Lung Cancer
Interventions: DRUG: Vilanterol and Umeclidinium Bromide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Association Between Digital Eye Syndrome With Binocular Vision and the Ocular Surface in Higher Education Students in the Area of Health Technologies
Status: NOT_YET_RECRUITING
Conditions: Digital Eye Strain
Interventions: OTHER: Exposure|DIAGNOSTIC_TEST: Orthoptic assessment (Outcome measure)|DIAGNOSTIC_TEST: Tear film Break Up Time (BUT) test (Outcome measure)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Selective Coronary Vein Sampling in Left Bundle Branch Block and CRT
Status: UNKNOWN
Conditions: Heart Failure
Interventions: PROCEDURE: Blood sampling and exercise protocol pre and post CRT implant|PROCEDURE: Peripheral blood sampling|PROCEDURE: Central blood sampling pre and post CRT implant|PROCEDURE: Central blood sampling on one occasion and exercise protocol and 6 month peripheral sampling
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Structured Online Contraceptive Counseling (LOWE Trial) at Emergency Contraception (EC) Pharmacy Provision LOWE+EC=LOWEC
Status: NOT_YET_RECRUITING
Conditions: Contraception
Interventions: OTHER: Online counseling and invitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Transcutaneous Auricular Vagal Nerve Stimulation for Functional Dyspepsia With Sleep Disturbances: a Randomized Controlled Trial
Status: RECRUITING
Conditions: Functional Dyspepsia|Sleep Disturbances
Interventions: DEVICE: Transcutaneous Auricular Vagal Nerve Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Mechanical Stapler for Aortic Anastomoses
Status: UNKNOWN
Conditions: Aortic Aneurysm, Abdominal|Leriche Syndrome
Interventions: PROCEDURE: AAA or AF/IB (end-to-end) in patients with Leriche Syndrome
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Study of Osseotite Certain Tapered Prevails vs. Osseotite Certain Tapered
Status: COMPLETED
Conditions: Partial Edentulism|Tooth Disease
Interventions: DEVICE: Osseotite Certain Tapered Prevail|DEVICE: Osseotite Certain Tapered
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Carvedilol for the Prevention of Anthracycline/Anti-HER2 Therapy Associated Cardiotoxicity Among Women With HER2-Positive Breast Cancer Using Myocardial Strain Imaging for Early Risk Stratification
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Carvedilol|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Vorinostat, Bortezomib and Dexamethasone in Multiple Myeloma (MUKFour)
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Vorinostat Velcade Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Impact of JJVC Senofilcon A - Based Contact Lens With New UV-blocker on Day and Night Driving Performance
Status: COMPLETED
Conditions: Visual Performance
Interventions: DEVICE: Investigational Contact Lens|DEVICE: Commercial ACUVUE OASYS|DEVICE: Commercial ACUVUE OASYS and Spectacles
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Radiofrequency Ablation Versus Liver Resection for Elderly Patients With Hepatocellular Carcinoma (HCC) Within the Milan Criteria
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma
Interventions: PROCEDURE: HR|PROCEDURE: RFA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mediterranean Diet, Circuit Resistance Training, Empagliflozin in Elderly With Type 2 Diabetes: a Study Protocol
Status: UNKNOWN
Conditions: Diabetes Mellitus, Type 2|Sarcopenia|Weight Loss|Frailty
Interventions: BEHAVIORAL: Circuit resistance training (CRT)|BEHAVIORAL: Vegeterranean diet (V-Med diet)|DRUG: Empagliflozin 10 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tavo and Pembrolizumab in Patients With Stage III/IV Melanoma Progressing on Either Pembrolizumab or Nivolumab Treatment
Status: ACTIVE_NOT_RECRUITING
Conditions: Stage III/IV Melanoma
Interventions: BIOLOGICAL: tavokinogene telseplasmid|BIOLOGICAL: Pembrolizumab|DEVICE: ImmunoPulse
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study to Evaluate Proellex in the Treatment of Premenopausal Women With Symptomatic Endometriosis
Status: TERMINATED
Conditions: Endometriosis
Interventions: DRUG: Proellex 25 mg|DRUG: Placebo|DRUG: Proellex 50 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vitamin C Infusion for Treatment in Sepsis Induced Acute Lung Injury
Status: COMPLETED
Conditions: Acute Lung Injury|Sepsis
Interventions: DRUG: Ascorbic Acid|DRUG: Placebo: 5% Dextrose in water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Switching From a Stimulant Medication to Atomoxetine in Children and Adolescents With ADHD
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: DRUG: Atomoxetine Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hydrodynamic Ultrasonic Maxillary Sinus Floor Elevation Technique Versus Closed Maxillary Sinus Floor Elevation.
Status: UNKNOWN
Conditions: Dental Implant
Interventions: PROCEDURE: Sinus Floor Elevation Between Hydrodynamic Ultrasonic Maxillary Sinus Floor Elevation Technique|PROCEDURE: closed maxillary sinus lift
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Study of Olaparib Combined With Abiraterone and Prednisone in mHSPC Patients With HRR Gene Mutation
Status: RECRUITING
Conditions: Prostate Cancer|Prostate Carcinoma|Metastatic Prostate Cancer
Interventions: DRUG: Olaparib tablet|DRUG: Abiraterone acetate|DRUG: Prednisone tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hypofractionated vs. Conventionally Fractionated Concurrent CRT for Unresectable Stage III NSCLC
Status: UNKNOWN
Conditions: Unresectable Stage III Non-small-cell Lung Cancer
Interventions: RADIATION: Arm1 (Hypofractionated radiotherapy)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Compare Busulfan-fludarabine With Thiotepa-fludarabine Regimen in Allogeneic Transplantation for Myelofibrosis
Status: COMPLETED
Conditions: Myelofibrosis
Interventions: DRUG: A: Fludarabine + Busulphan|DRUG: B: Fludarabine + Thiotepa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Double-Blind Placebo-Controlled CIN Trial
Status: TERMINATED
Conditions: Acute Kidney Injury
Interventions: DRUG: Iopamidol 300 (Contrast)|DRUG: Placebo (Normal Saline)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Modification of Epilepsy Screen Questionnaire and Treatment Feasibility Evaluation
Status: NOT_YET_RECRUITING
Conditions: Epilepsy
Interventions: DRUG: Zonisamide 100mg|DRUG: Levetiracetam 500mg|DRUG: LamoTRIgine 50mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Chemoradiotherapy Combined With PD-1 Antibody in Locally Advanced Esophageal Cancer
Status: UNKNOWN
Conditions: Esophagus Cancer
Interventions: DRUG: Teripalimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Physician Peer Coaching on Burnout in Hospital-Based Physicians: A Pilot Randomized Clinical Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Burn Out
Interventions: BEHAVIORAL: Physician Led Professional Coaching|BEHAVIORAL: Delayed Physician Led Professional Coaching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Randomized, Controlled, Multicenter Study of Extracellular Vesicles From Human Adipose Tissue Promoting Wound Healing
Status: RECRUITING
Conditions: Wound Heal
Interventions: BIOLOGICAL: adipose tissue derived extracellular vesicles (AT-EVs)|DRUG: Hyaluronic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of JK07 in Subjects With Heart Failure With Reduced Ejection Fraction (HFrEF)
Status: COMPLETED
Conditions: Heart Failure With Reduced Ejection Fraction
Interventions: DRUG: JK07|DRUG: Matching Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Adjusted Calculation of Heparin and Protamin Dosing and Correlation With Postoperative Bleeding and Transfusions
Status: UNKNOWN
Conditions: Cardiac Surgery|Bleeding|Transfusion|Protamine Sulfate|Heparin
Interventions: OTHER: HeProCalc algorithm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Binge Focused Therapy: A Guided, Self-help, Group-based Approach for Binge Eating Disorder
Status: COMPLETED
Conditions: Binge-Eating Disorder|Eating Disorder
Interventions: BEHAVIORAL: Binge Focused Therapy (BFT) Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Shensongyangxin Capsule in the Treatment of Sinus Bradycardia With Premature Ventricular Contractions
Status: UNKNOWN
Conditions: Premature Ventricular Contraction
Interventions: DRUG: Shensong Yangxin capsule|DRUG: placebo Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Investigate the Effect of the CREON2000A on Asthma Control in Children With Mild to Moderate Persistent Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DEVICE: CREON2000A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Pre-sleep or Post-exercise Protein During 12 Weeks of Resistance Exercise Training
Status: COMPLETED
Conditions: Aging
Interventions: DIETARY_SUPPLEMENT: Protein|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Telehealth 2.0: Evaluating Effectiveness and Engagement Strategies for CPT-Text for PTSD
Status: RECRUITING
Conditions: Posttraumatic Stress Disorder
Interventions: BEHAVIORAL: CPT-Text|BEHAVIORAL: Culturally Informed Trauma Treatment (CITT)|BEHAVIORAL: Retention Incentive|BEHAVIORAL: Reminder as Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of Relatlimab Plus Nivolumab in Combination With Chemotherapy vs. Nivolumab in Combination With Chemotherapy as First Line Treatment for Participants With Stage IV or Recurrent Non-small Cell Lung Cancer (NSCLC)
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-small Cell Lung Cancer|Recurrent Non-small Cell Lung Cancer|Metastatic Non-small Cell Lung Cancer
Interventions: BIOLOGICAL: Nivolumab|BIOLOGICAL: Relatlimab|DRUG: Carboplatin|DRUG: Cisplatin|DRUG: Paclitaxel|DRUG: Nab-Paclitaxel|DRUG: Pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Continuation Protocol for ZEN003694 in Patients Experiencing Clinical Benefit While Enrolled in a ZEN003694 Protocol
Status: ENROLLING_BY_INVITATION
Conditions: mCRPC
Interventions: DRUG: ZEN003694|DRUG: Enzalutamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I Study Evaluating Safety and Tolerability of Escalating Single and Multiple Doses of of PIPE-307 and Food Effect in Healthy Volunteers
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DRUG: PIPE-307|DRUG: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Safety and Efficacy of Qishen Granules Among Patients With Chronic Heart Failure
Status: UNKNOWN
Conditions: Heart Failure|Cardiovascular Diseases
Interventions: DRUG: Qishen Granules|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of the Vacucis Candida® Autovaccine
Status: NOT_YET_RECRUITING
Conditions: Oral Candidiasis|Oral Candidiasis Recurrent|Radiotherapy; Complications|Candida Albicans Infection|Microbial Colonization|Xerostomia
Interventions: DRUG: Vacucis autovaccine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Metformin in Assisted Reproduction-MET-AR-study
Status: TERMINATED
Conditions: Polycystic Ovary Syndrome
Interventions: DRUG: Metformin / Placebo treatment for 4 months
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of a Brief Mental Exercise on Emotional Processing
Status: COMPLETED
Conditions: Emotional Processing|Mental Exercise
Interventions: BEHAVIORAL: Three good things exercise|BEHAVIORAL: Placebo exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Apixaban for Secondary Prevention of Thromboembolism Among Patients With AntiphosPholipid Syndrome
Status: COMPLETED
Conditions: Antiphospholipid Syndrome|Thrombosis
Interventions: DRUG: Apixaban|DRUG: Warfarin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Long-term Follow-up of Subjects Treated With CARv3-TEAM-E T Cells
Status: NOT_YET_RECRUITING
Conditions: Glioblastoma Recurrent, EGFR vIII Mutant|Newly Diagnosed Glioblastoma, EGFRvIII Mutant|Recurrent Glioblastoma, EGFR vIII Negative
Interventions: DIAGNOSTIC_TEST: Disease assessments|PROCEDURE: Tumor Biopsy|DIAGNOSTIC_TEST: Blood test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Extracorporeal Photopheresis in Lung Transplant Rejection for Cystic Fibrosis (CF) Patients
Status: UNKNOWN
Conditions: Lung Transplant Rejection
Interventions: DEVICE: photopheresis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Fractional Carbon Dioxide Laser,Topical Corticosteroid and Narrow Band Ultraviolet B in Treatment of Stable Vitiligo
Status: UNKNOWN
Conditions: Vitiligo
Interventions: PROCEDURE: fractional carbon dioxide(CO2) laser|DRUG: Topical corticosteroid|RADIATION: Ultraviolet B narrow band
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A First in Human Study of the Safety and Tolerability of Single and Multiple Doses of SPR741 in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: SPR741|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: mTORC1/2 Inhibitor AZD2014 or the Oral AKT Inhibitor AZD5363 for Recurrent Endometrial and Ovarian
Status: ACTIVE_NOT_RECRUITING
Conditions: BRCA1 Mutation Carrier|BRCA2 Mutation Carrier|Endometrial Adenocarcinoma|Estrogen Receptor Negative|HER2/Neu Negative|High Grade Ovarian Serous Adenocarcinoma|Progesterone Receptor Negative|Recurrent Breast Carcinoma|Recurrent Fallopian Tube Carcinoma|Recurrent Ovarian Carcinoma|Recurrent Primary Peritoneal Carcinoma|Recurrent Uterine Corpus Carcinoma|Stage III Uterine Corpus Cancer AJCC v7|Stage IV Breast Cancer AJCC v6 and v7|Stage IV Uterine Corpus Cancer AJCC v7|Triple-Negative Breast Carcinoma
Interventions: DRUG: Capivasertib|OTHER: Laboratory Biomarker Analysis|DRUG: Olaparib|OTHER: Pharmacological Study|DRUG: Vistusertib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Therapeutic Control of Aspirin-Exacerbated Respiratory Disease (Aspirin)
Status: COMPLETED
Conditions: Asthma, Aspirin-Induced|Aspirin Exacerbated Asthma
Interventions: DRUG: Placebo Oral Tablet|DRUG: Prasugrel Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Phase I Clinical Trial With Whole Virus Inactivated Influenza H5N1 Vaccine in Healthy Adolescents and Adults
Status: WITHDRAWN
Conditions: Healthy
Interventions: BIOLOGICAL: 7.5μg /0.5ml|BIOLOGICAL: 15.0μg /0.5ml|BIOLOGICAL: 30.0μg /0.5ml|BIOLOGICAL: 0/0.5ml placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: OXN PR Tablet 5/2.5 mg and20/10 mg PK Study in Chinese Moderate to Severe Chronic Non-malignant Patients
Status: COMPLETED
Conditions: Chronic Pain
Interventions: DRUG: OXN PR tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Phase I/II Study of Mis-Matched Immune Cells (AlloStim) in Patients With Advanced Hematological Malignancy
Status: COMPLETED
Conditions: Hematological Malignancy|Leukemia|Lymphoma|Multiple Myeloma
Interventions: BIOLOGICAL: AlloStim|BIOLOGICAL: AlloStim|BIOLOGICAL: AlloStim|BIOLOGICAL: AlloStim
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hemodynamic and Respiratory Variations During Laparoscopic Surgery With and Without Deep Neuromuscular Blockade.
Status: COMPLETED
Conditions: Intraoperative Complications|Postoperative Complications|Laparoscopy|Surgical Complications From General Anesthesia|Ventilator-Induced Lung Injury
Interventions: DRUG: Rocuronium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Dose-ranging, PK, Safety, Efficacy Study of Osanetant in Patients With Moderate/Severe VMS Associated With Menopause
Status: COMPLETED
Conditions: Post-menopausal Vasomotor Symptoms
Interventions: DRUG: ACER-801 50 mg BID|DRUG: ACER-801 100 mg BID|DRUG: ACER-801 200 mg BID|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Patient-controlled Intravenous Analgesia Combined With Different Opioid Receptors for Gastrointestinal Surgery
Status: COMPLETED
Conditions: Gastrointestinal Surgery
Interventions: DRUG: sufentanil + nalbuphine|DRUG: Sufentanil|DRUG: hydromorphone + nalbuphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Empathy in Action: Sunshine Calls for Life With Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Diabetes|Mental Health|Health Behavior
Interventions: BEHAVIORAL: Empathy in Action for life with diabetes.|BEHAVIORAL: Control Phase 2 Materials Only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ectopic Fat in Singaporean Women - the Culprit Leading to Gestational Diabetes, Metabolic Syndrome, and Type 2 Diabetes (TANGO Study)
Status: COMPLETED
Conditions: Non-Alcoholic Fatty Liver Disease
Interventions: OTHER: Lifestyle Advice|OTHER: Diet Intervention|OTHER: OCFA Meal-Based Diet-Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: A Efficacy and Safety Study of Adefovir Dipivoxil to Treat Chinese Patients With HBeAg+ve Chronic Hepatitis B
Status: COMPLETED
Conditions: Chronic Hepatitis B
Interventions: DRUG: AAAA|DRUG: AAPA|DRUG: PAAA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Flow Rate Effect Respimat Inhaler Versus a Metered Dose Inhaler Using Berodual in Patients With Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive|Asthma
Interventions: DEVICE: Berodual Respimat|DEVICE: Berodual HFA-MDI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Postpartum Adherence Clubs to Enhance Support: the PACER Study
Status: COMPLETED
Conditions: HIV
Interventions: OTHER: Community-based Adherence Clubs|OTHER: Standard of Care for Mothers|OTHER: Standard of Care for Infants
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Quantitative Detection of Circulating Donor-Specific DNA in Organ Transplant Recipients (DTRT-Multi-Center Study)
Status: COMPLETED
Conditions: Cardiovascular Disease|Acute Rejection of Cardiac Transplant|Cardiac Transplant Rejection|Heart Transplant Failure and Rejection
Interventions: DIAGNOSTIC_TEST: Blood Draw of up to 10 ml
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Electrical Pharyngeal Stimulation for Dysphagia Therapy in Tracheostomized Stroke Patients
Status: COMPLETED
Conditions: Stroke|Dysphagia
Interventions: DEVICE: Electrical pharyngeal stimulation|DEVICE: Sham stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vaccine Therapy in Treating Patients With Metastatic Melanoma of the Eye
Status: COMPLETED
Conditions: Extraocular Extension Melanoma|Recurrent Intraocular Melanoma
Interventions: DRUG: gp100 antigen|DRUG: interleukin-2|DRUG: MART-1 antigen|DRUG: Montanide ISA-51
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Study Assessing Safety and Efficacy of PG324 Ophthalmic Solution in Patients With Elevated Intraocular Pressure
Status: COMPLETED
Conditions: Open Angle Glaucoma|Ocular Hypertension
Interventions: DRUG: PG324 Ophthalmic Solution 0.01%|DRUG: PG324 Ophthalmic Solution 0.02%|DRUG: Netarsudil (AR-13324) Ophthalmic Solution 0.02%|DRUG: Latanoprost Ophthalmic Solution 0.005%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Treatment With High Flow Nasal Cannulas on Respiratory Pattern and Work of Breathing Among Healthy Subjects
Status: UNKNOWN
Conditions: Respiratory Failure
Interventions: DEVICE: High flow nasal cannulas|DEVICE: Conventional flow via nasal prongs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: S9626: Megestrol in Treating Hot Flashes Following Treatment for Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer|Hot Flashes
Interventions: DRUG: Megestrol Acetate 20mg/day|DRUG: Megestrol Acetate 40 mg/day|DRUG: Megestrol Acetate Placebo 20 mg/day|DRUG: Megestrol Acetate Placebo 40 mg/day
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of "Sekanjabin e Safarjali" (Quince Oxymel) in the Prevention of Migraine Attacks
Status: UNKNOWN
Conditions: Migraine Headache|Gastric Diseases
Interventions: DRUG: propranolol|DRUG: Quince's oxymel|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety, Reactogenicity and Immunogenicity Study of Different Formulations of GlaxoSmithKline (GSK) Biologicals' Investigational RSV Vaccine (GSK3003891A), in Healthy Women
Status: COMPLETED
Conditions: Respiratory Syncytial Virus Infections
Interventions: BIOLOGICAL: RSV vaccine GSK3003895A (formulation 1)|BIOLOGICAL: RSV vaccine GSK3003898A (formulation 2)|BIOLOGICAL: RSV vaccine GSK3003899A (formulation 3)|BIOLOGICAL: Boostrix
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Application of Large Language Model in Emergency Chest Pain Triage
Status: RECRUITING
Conditions: Chest Pain
Interventions: DIAGNOSTIC_TEST: Application of large language model in emergency chest pain triage.|DIAGNOSTIC_TEST: According to the normal procedures to receive medical treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effects of Square-stepping Exercise Training on the Attention, Dynamic Balance and Lower Extremity Motor Coordination
Status: COMPLETED
Conditions: Sedentary Healthy Young Individuals
Interventions: OTHER: Exercise Trainig
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE