pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Factors That Influence Blood Vessel Regulation During Exercise in Humans
Status: COMPLETED
Conditions: Ischemic Preconditioning|Dietary Exposure
Interventions: PROCEDURE: Ischemic preconditioning|PROCEDURE: Ischemic preconditioning control|DIETARY_SUPPLEMENT: Low fat meal|DIETARY_SUPPLEMENT: High fat meal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study Using Spray Skin Protector Versus Conventional Treatment to Prevent Acute Radiodermatitis.
Status: ENROLLING_BY_INVITATION
Conditions: Radiodermatitis|Injury, Radiation
Interventions: OTHER: Spray skin protector|OTHER: moisturizer Dnativ Revita derm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Use of Audio Recordings of Self-Hypnosis and Meditation for Fatigue Management in Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis|Fatigue
Interventions: BEHAVIORAL: Self-Hypnosis (HYP)|BEHAVIORAL: Mindfulness Meditation (MM)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Analgesic Response to Opioids in Patients With Fibromyalgia After Conventional Acupuncture Versus Sham Acupuncture
Status: NOT_YET_RECRUITING
Conditions: Fibromyalgia
Interventions: PROCEDURE: Traditional/Sham Acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of Pentoxifylline on Liver Function Tests in Fatty Liver Disease
Status: COMPLETED
Conditions: Fatty Liver
Interventions: DRUG: Pentoxifylline|BEHAVIORAL: Lifestyle modification
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: BIOLUX P-I First in Man Study
Status: COMPLETED
Conditions: Atherosclerosis|Arteriosclerosis|Vascular Disease|Peripheral Artery Disease
Interventions: DEVICE: Passeo-18 Lux DRB|DEVICE: Standard PTA (POBA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of the Anti-oxidant N-acetylcysteine on Beta-cell Function in Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes|Oxidative Stress
Interventions: DRUG: N-acetylcysteine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Dapagliflozin in Physical Exercise in Type 1 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: DRUG: Forxiga 10mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of mRNA-1647 Cytomegalovirus Vaccine in Liver Transplant Candidates and Recipients
Status: WITHDRAWN
Conditions: Cytomegalovirus Infection
Interventions: BIOLOGICAL: mRNA-1647|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Phase 1 Study of HS130 in Combination With Viagenpumatucel-L (HS110) in Patients With Solid Tumors
Status: COMPLETED
Conditions: Advanced Solid Tumor
Interventions: BIOLOGICAL: HS-110 (viagenpumatucel-L)|BIOLOGICAL: HS-130
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Heart Rate Variability, Vagus Nerve and Cancer
Status: TERMINATED
Conditions: Lung Cancer|Colorectal Cancer|Multiple Myeloma|Non Hodgkin Lymphoma
Interventions: OTHER: Osteopathic intervention|BIOLOGICAL: CRP assessment|BEHAVIORAL: QLQ-C30 questionnaire
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Trial of Lapatinib and Weekly Paclitaxel for Advanced Urothelial Cancer
Status: WITHDRAWN
Conditions: Urothelial Cancer|Bladder Cancer
Interventions: DRUG: Lapatinib and Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Timed Release Tablet Prednisone in Polymyalgia Rheumatica
Status: COMPLETED
Conditions: Polymyalgia Rheumatica
Interventions: DRUG: Timed Release Tablet Prednisone|DRUG: Prednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single Dose Study of the Fluticasone/Salmeterol (500/50 μg) Administered With Elpenhaler® Versus Diskus®
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Elpenhaler active - Diskus placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Detection of Standard Colonoscopy, CAD-EYE and Combined CAD-EYE and G-EYE® Aided Colonoscopy
Status: UNKNOWN
Conditions: Colorectal Cancer|Adenoma
Interventions: DEVICE: Standard Colonoscopy|DEVICE: G-EYE Colonoscopy|DEVICE: CAD-EYE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Central Venous to Arterial CO2 Difference and Low Cardiac Output Syndrome Related Outcomes in Children After Cardiac Surgery
Status: COMPLETED
Conditions: Congenital Heart Disease|Perioperative/Postoperative Complications|Lactate Blood Increase
Interventions: DIAGNOSTIC_TEST: arterial and central venous blood gas analysis, lactate
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Providing Peer Mother Support Through Cell Phone and Group Meetings to Increase Exclusive Breastfeeding in Kenya
Status: COMPLETED
Conditions: Breastfeeding
Interventions: BEHAVIORAL: Peer mother support for continued exclusive breastfeeding
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Combined Effects of Non-statin Treatments on Apolipoprotein A-I Up-Regulation (CENTAUR): A Feasibility Study
Status: COMPLETED
Conditions: Dyslipidemia
Interventions: DRUG: Atorvastatin|DRUG: ABT335|DRUG: ER Niacin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Post-Market Clinical Follow-Up Study to Confirm Clinical Performance and Safety of the Codman Enterprise® 2 Vascular Reconstruction Device in the Endovascular Treatment of Intracranial Aneurysms
Status: TERMINATED
Conditions: Intracranial Aneurysm
Interventions: DEVICE: Enterprise 2 Vascular Reconstruction Device
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Efficacy of Azvudine and Paxlovid in High-risk Patients With COVID-19: A Prospective Randomized Controlled Trial
Status: RECRUITING
Conditions: SARS-CoV-2 Infection
Interventions: DRUG: Azvudine|DRUG: Paxlovid group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lifestyle Intervention of Food and Exercise for Lymphoma Survivors
Status: RECRUITING
Conditions: Non Hodgkin Lymphoma|Hodgkin Lymphoma
Interventions: BEHAVIORAL: LIFE-L Mediterranean Diet|BEHAVIORAL: LIFE-L Home-Based Exercise Program|BEHAVIORAL: Supportive Materials
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study Exploring the Supportive Effect of Acarbose in Weight Management
Status: ACTIVE_NOT_RECRUITING
Conditions: Overweight or Obesity
Interventions: DRUG: EMP16-120/40|DRUG: MR orlistat 120 mg|DRUG: Conventional orlistat 120 mg,|DRUG: EMP16-60/20|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Relapse Rate After 12 Weeks Verses 20 Weeks Steroid Therapy for the Management of First Episode of Steroid Sensitive Nephrotic Syndrome
Status: UNKNOWN
Conditions: Steroid-Sensitive Nephrotic Syndrome
Interventions: DRUG: Prednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Hypertonic Saline (6%) Versus Isotonic Saline (0.9%) in Bronchiectasis
Status: UNKNOWN
Conditions: Bronchiectasis
Interventions: OTHER: Hypertonic saline|OTHER: Isotonic saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Topical Ruxolitinib Evaluation in Chronic Hand Eczema Study 2
Status: WITHDRAWN
Conditions: Chronic Hand Eczema (CHE)
Interventions: DRUG: Ruxolitinib cream|DRUG: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Panchromoendoscopy Using Oral Indigo Carmine Mixed With Polyethylene Glycol Prep
Status: COMPLETED
Conditions: Colonic Polyps
Interventions: DRUG: Chromoendoscopy (Indigo Carmine)|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Effects of 3% Sodium Chloride on Post-operative Dysphagia Following Anterior Cervical Spine Surgery
Status: WITHDRAWN
Conditions: Dysphagia
Interventions: DRUG: 3% Sodium Chloride|DRUG: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Defining the Physiological Mechanisms of Risk Genes for Hyperglycaemia, Insulin Resistance and Type 2 Diabetes
Status: UNKNOWN
Conditions: Type 2 Diabetes
Interventions: OTHER: 4 Hour Frequently Sampled Oral Glucose Tolerance Test|OTHER: Isoglycaemic Clamp
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Amplification of Autologous Epidermal Cells to Repair Large Area Deep Wounds
Status: RECRUITING
Conditions: Autologous Epidermal Cell Transplantation
Interventions: PROCEDURE: Cultured autologous epidermal cell membrane
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Slow Wave Induction by Propofol to Eliminate Depression (SWIPED)
Status: RECRUITING
Conditions: Treatment Resistant Depression
Interventions: DRUG: Propofol|DIAGNOSTIC_TEST: Electroencephalography (EEG)|DIAGNOSTIC_TEST: Slow-Wave Activity
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Gender Related Differences in the Acute Effects of Delta-9-Tetrahydrocannabinol in Healthy Humans: Sub-Study I
Status: RECRUITING
Conditions: Cannabis
Interventions: DRUG: Placebo|DRUG: Dronabinol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: BivaliRudin in Acute Myocardial Infarction vs Glycoprotein IIb/IIIa and Heparin :a Randomised Controlled Trial.
Status: COMPLETED
Conditions: Acute Myocardial Infarction|Percutaneous Coronary Intervention
Interventions: DRUG: Bivalirudin|DRUG: heparin|DRUG: heparin plus tirofiban
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Performance and Tolerance of Cyto-selective Difluoroethane-based Cryotherapy in th Treatment of Brown Spots (Solar and Senile Lentigines, Post-Inflammatory Hyperpigmentation) on the Face and Hands of Asian Ethnicity Skins
Status: NOT_YET_RECRUITING
Conditions: Solar Lentigo|Senile Lentigo
Interventions: DEVICE: prototypes 1 everyday|DEVICE: prototypes 1 every week|DEVICE: prototypes 1 every two weeks|DEVICE: prototypes 2 every two weeks|DEVICE: prototypes 3 every two weeks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Antibiotic Therapy After Incision and Drainage for Abscess
Status: WITHDRAWN
Conditions: Abscess
Interventions: PROCEDURE: Incision and drainage|DRUG: Trimethoprim/Sulfamethoxazole (Bactrim)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Motivation in Learning Medical Terminology
Status: RECRUITING
Conditions: Education|Medical Terminology Education
Interventions: OTHER: Alternative teaching method: Funny Scenario-Based Education|OTHER: Alternative teaching method: Mind-mapping Education
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Spinal Cord Stimulation in Patients With Post-Laminectomy Syndrome in Testing Phase
Status: COMPLETED
Conditions: Laminectomy|Post-laminectomy Syndrome|Spinal Cord Syndrome|Failed Back Surgery Syndrome
Interventions: DEVICE: spinal cord stimulation conventional|DEVICE: spinal cord stimulation experimental
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Virtual Reality Immersive Method for Spider (Phobia) Exposure Therapy (VIMSE)
Status: COMPLETED
Conditions: Phobia, Specific
Interventions: OTHER: OST treatment with in-vivo spiders|OTHER: VR-OST treatment with virtual spiders
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Role of Frontal Cortex in the Pathophysiology of Gilles de la Tourette Syndrome (GTS)
Status: COMPLETED
Conditions: Tourette Syndrome
Interventions: PROCEDURE: Electroencephalographic recordings
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Bioavailability of BIBR 1048 MS With and Without Pantoprazole Under Influence of Food in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BIBR 1048 MS|DRUG: Pantoprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate SAGE-217 in Participants With Bipolar I/II Disorder With a Current Major Depressive Episode
Status: COMPLETED
Conditions: Bipolar Disorder I|Bipolar Disorder II|Major Depressive Episode
Interventions: DRUG: SAGE-217|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BI 655066 (Risankizumab) Proof of Concept Dose Finding Study in Ankylosing Spondylitis (AS)
Status: COMPLETED
Conditions: Ankylosing Spondylitis (AS)
Interventions: DRUG: placebo for risankizumab|DRUG: risankizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Comparative Bioavailability of Myfenax® and CellCept® in Kidney Transplant Patients
Status: TERMINATED
Conditions: Stable Renal Transplant Recipients
Interventions: DRUG: mycophenolate mofetil (Myfenax)|DRUG: mycophenolate mofetil (Cellcept)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combined Sertraline and Ketoprofen Administration in Major Depressive Disorder
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: COMBINATION_PRODUCT: Combined Sertraline & Ketoprofen|OTHER: Interleukins in MDD after treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Participation in Screening for Cervical Cancer: Interest of a Self-sampling Device Provided by the General Practitioner
Status: COMPLETED
Conditions: Malignant Tumor of Cervix|Cervical Intraepithelial Neoplasia
Interventions: DEVICE: Vaginal self-sampling brush
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Home Respiratory Polygraphy in Childhood Sleep Apnea-Hypopnea Syndrome (CHILDSLEEP).
Status: UNKNOWN
Conditions: Sleep Apnea|Home Respiratory Polygraphy Sleep Study|Childhood Sleep Apnea|Polysomnography|Therapeutic Decision
Interventions: DIAGNOSTIC_TEST: Home respiratory polygraphy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Cognitive Behavioral Therapy on Adherence and Depression (CBT-AD) Among HIV/AIDS Patients
Status: RECRUITING
Conditions: Depression|Medication Adherence
Interventions: BEHAVIORAL: Cognitive Behavioral Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy and Safety of Methylene Blue in the Treatment of Severe Septic Shock
Status: NOT_YET_RECRUITING
Conditions: Septic Shock|Methylene Blue|Sepsis
Interventions: DRUG: Methylene Blue Intervention Group|DRUG: Normal Saline Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Premature Fatigue in Veterans With Heart Failure: Neuronal Influences
Status: COMPLETED
Conditions: Heart Failure
Interventions: DEVICE: Electrical and Magnetic Nerve Stimulators|DRUG: Intrathecal Fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Involved Field Elective Volume De-Intensification Radiation Therapy for Head and Neck Cancer
Status: COMPLETED
Conditions: Head and Neck Cancer|Carcinoma, Squamous Cell|Neoplasms, Oral|Neoplasms, Pharyngeal
Interventions: RADIATION: Intensity Modulated Radiation Therapy|DRUG: chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aerosolized Antibiotics in the Treatment of Ventilator Associated Pneumonia
Status: TERMINATED
Conditions: Pneumonia, Ventilator-Associated
Interventions: DRUG: Aerosolized Tobramycin or Vancomycin|DRUG: Aerosolized Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of the Sana Device on Fibromyalgia Symptoms
Status: NOT_YET_RECRUITING
Conditions: Fibromyalgia|Pain, Chronic|Quality of Life
Interventions: DEVICE: Sana Device|DRUG: Sana Device (Control)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Vitamin D3 Supplementation on Insulin Resistance- The DIR Study
Status: COMPLETED
Conditions: Sub-optimal Vitamin D Status|Pre-diabetes|Insulin Resistance
Interventions: DIETARY_SUPPLEMENT: Vitamin D3 supplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Apremilast to Evaluate the Safety and Effectiveness for Patients With Rheumatoid Arthritis
Status: TERMINATED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Apremilast 30 mg|DRUG: Apremilast 20 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Evaluate the Endoscopic Ultrasound Guided Celiac Plexus Block for Treatment of Pain in Chronic Pancreatitis
Status: COMPLETED
Conditions: Pancreatitis, Chronic|Abdominal Pain
Interventions: PROCEDURE: EUS-celiac ganglia block (EUS-CGB)|PROCEDURE: EUS-celiac plexus block (EUS-CPB)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: GP Plus Adebrelimab Versus GP Neoadjuvant Chemotherapy for Nasopharyngeal Carcinoma
Status: RECRUITING
Conditions: Nasopharyngeal Carcinoma
Interventions: DRUG: GP|DRUG: Adebrelimab|DRUG: concurrent chemoradiotherapy (CCRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Autologous Vaccination of Stage 4 Renal Cell Carcinoma Combined With Sunitinib
Status: UNKNOWN
Conditions: Renal Cell Cancer
Interventions: BIOLOGICAL: Autologous renal cell vaccine based on DNP modified cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PEMF: an Adjunct Therapy for Anterior Uveitis
Status: COMPLETED
Conditions: Anterior Uveitis|Iritis
Interventions: DEVICE: PEMF|DEVICE: PEMF Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pre-operative Bowel Preparation Prior to Minimally Invasive Sacral Colpopexy
Status: COMPLETED
Conditions: Pelvic Organ Prolapse|Prolapse
Interventions: OTHER: Bowel preparation|OTHER: No bowel preparation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effective Pain Management During Shoulder Replacement Surgery With EXPAREL
Status: WITHDRAWN
Conditions: Pain, Postoperative|Shoulder Osteoarthritis
Interventions: DRUG: local infiltration of liposomal bupivacaine|OTHER: continuous infusion of ropivacaine interscalene nerve block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Rifampicin Combination Therapy Versus Monotherapy for Staphylococcal Prosthetic Joint Infection
Status: RECRUITING
Conditions: Prosthetic-joint Infection|Infection Hip|Infection; Knee, Joint
Interventions: DRUG: Clindamycin|DRUG: Rifampicin and levofloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial to Assess a Wearable Patch's Functioning to Detect Medication Ingestion
Status: COMPLETED
Conditions: Mental Disorder|Schizophrenia|Major Depressive Disorder|Bipolar I Disorder
Interventions: DRUG: Placebo IEM tablet|DRUG: Abilify MyCite®|DEVICE: D-Tect Patch
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Folate Augmentation of Treatment - Evaluation for Depression: a Randomised Controlled Trial
Status: COMPLETED
Conditions: Depression
Interventions: DRUG: Folic Acid|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Hyperbaric Oxygen Therapy on Surgical Wound Healing
Status: UNKNOWN
Conditions: Edema|Ecchymosis
Interventions: DRUG: Hyperbaric oxygen treatment|DRUG: Air sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Efficacy of Polidocanol Injections as a Treatment of Chronic Achilles. Tendinopathy
Status: COMPLETED
Conditions: Chronic Achilles Tendinopathy
Interventions: DRUG: Aethoxysclerol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Bilistick Point-of-care System 2.0 Bilirubin Validation
Status: RECRUITING
Conditions: Neonatal Screening|Kernicterus|Newborn Jaundice|Point-of-Care Testing
Interventions: DIAGNOSTIC_TEST: Bilistick System 2.0 point-of-care testing device
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of Neoadjuvant SHR6390 in Combination With Anastrozole, Pyrotinib, and Trastuzumab in Patients With ER+/HER2+ Breast Cancer.
Status: UNKNOWN
Conditions: Breast Cancer|HER2-positive Breast Cancer|ER-positive Breast Cancer
Interventions: DRUG: SHR6390|DRUG: Anastrozole|DRUG: Pyrotinib|DRUG: Trastuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Test 2 Doses of GSK Biologicals' Oral Live Attenuated Human Rotavirus (HRV) Vaccine in Healthy Infants
Status: COMPLETED
Conditions: Infections, Rotavirus
Interventions: BIOLOGICAL: Rotavirus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Exercise Intensity on Vitamin D
Status: COMPLETED
Conditions: Down Syndrome|Vitamin D Deficiency
Interventions: OTHER: High intensity treamill exercise training.|OTHER: Moderate intensity treamill exercise training.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dielectric Properties of Matched Tissue Samples From Thoracic Malignancies and Corresponding Normal Tissues
Status: UNKNOWN
Conditions: Lung Cancer|Esophageal Cancer|Mesothelioma; Lung
Interventions: DEVICE: LCR Meter (Brand: Keysight, Serial Number:E498AL)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sensor Glove and Non-Invasive Vibrotactile Feedback Insole to Improve Hand Prostheses Functions and Embodiment
Status: COMPLETED
Conditions: Amputation; Traumatic, Hand
Interventions: DEVICE: FeetBack System Active|DEVICE: FeetBack System Passive
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Tracheal Intubation in Patient With Semi-rigid Collar Immobilization of the Cervical Spine: A Comparison of Fiberoptic Bronchoscope Assisted With Pentax-airway Scope and Fiberoptic Bronchoscope Alone
Status: COMPLETED
Conditions: Cholecystitis
Interventions: DEVICE: fiberoptic bronchoscope|DEVICE: pentax-airway scope|PROCEDURE: semi-rigid collar
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Application of Monitoring and Intervention Technologies in Suboptimal Health Status
Status: COMPLETED
Conditions: Suboptimal Health Status|Metabolic Abnormality
Interventions: DEVICE: meridian therapy instrument|OTHER: health information push technology|DEVICE: monitoring device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluation of a Tdap-IPV (Tetanus, Diphteria, Pertussis and Inactivated Polio) Vaccination Remedial Strategy on Vaccination Coverage in Patients 65 Years of Age or Older
Status: UNKNOWN
Conditions: Vaccination
Interventions: BIOLOGICAL: Remedial vaccination
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase Ⅰb/Ⅱ Clinical Study of SHR-A1811 Combined With Other Therapies in Patients With HER2 Low Advanced or Metastatic Breast Cancer.
Status: NOT_YET_RECRUITING
Conditions: HER2 Low Advanced or Metastatic Breast Cancer
Interventions: DRUG: SHR-A1811 & Dalpiciclib Isethionate Tablets|DRUG: SHR-A1811 & Fulvestrant|DRUG: SHR-A1811 & Bevacizumab injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Adverse Events of Subcutaneous (SC) Epcoritamab Administered in the Outpatient Setting in Adult Participants With Relapsed or Refractory Diffuse Large B-Cell Lymphoma and Classic Follicular Lymphoma
Status: RECRUITING
Conditions: Diffuse Large B-Cell Lymphoma|Classic Follicular Lymphoma
Interventions: DRUG: Epcoritamab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acute Feasibility Investigation of a New S-ICD Electrode
Status: COMPLETED
Conditions: Ventricular Fibrillation
Interventions: DEVICE: commercially released subcutaneous implantable cardioverter defibrillator (S-ICD) and the Investigational S-ICD Adapter.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Selecting the Best Ventilator Hyperinflation Settings
Status: COMPLETED
Conditions: Respiratory Failure|Respiration Disorders
Interventions: OTHER: VC-CMV20|OTHER: VC-CMV50|OTHER: PC-CMV1|OTHER: PC-CMV3|OTHER: PSV10|OTHER: PSV25
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Enoxolone in Major Depression - Biomarker-outcome Relationship
Status: RECRUITING
Conditions: Unipolar Depression
Interventions: DRUG: Enoxolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Onboarding Positives and PrEP Users to Engage Negatives (OPPEN): Peer-driven Education to Link YMSM of Color to PrEP
Status: RECRUITING
Conditions: HIV
Interventions: BEHAVIORAL: OPPEN|BEHAVIORAL: Control Condition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Vision, Attention and Reading in Neurofibromatosis Type 1 (NF1) Children
Status: UNKNOWN
Conditions: Neurofibromatosis Type 1
Interventions: OTHER: Neuropsychological evaluation|OTHER: Evaluation of the reading assistance technique
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: GALLEX 9: Safety and Tolerability of Oral Tesaglitazar When Added to Insulin Therapy in Patients With Type 2 Diabetes
Status: TERMINATED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Tesaglitazar
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of Ac225-PSMA Radioligand Therapy of Metastatic Castration-resistant Prostate Cancer
Status: UNKNOWN
Conditions: Metastatic Castration-resistant Prostate Cancer
Interventions: DRUG: 225Ac-PSMA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Restless Legs Syndrome With the Hypocretin Antagonist Suvorexant
Status: UNKNOWN
Conditions: Restless Legs Syndrome
Interventions: DRUG: Suvorexant|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Pharmacodynamic Study of AV-299 (Formerly SCH 900105) in Subjects With Advanced Solid Tumors Who Have Liver Metastases
Status: COMPLETED
Conditions: Malignant Solid Tumour|Liver Metastases
Interventions: BIOLOGICAL: AV-299
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Tranexamic Acid for Reducing Blood Loss and Blood Transfusion After Periacetabular Osteotomy
Status: COMPLETED
Conditions: Dysplasia, Congenital Hip
Interventions: DRUG: Tranexamic Acid|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial of Erbitux for Recurrent and Metastatic Mucinous Gastrointestinal Adenocarcinoma Involving the Peritoneal Surfaces
Status: COMPLETED
Conditions: Mucinous Gastrointestinal Adenocarcinoma
Interventions: DRUG: cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Role of Ga68-PSMA-11 PET Imaging in Prostate Cancer Patients Undergoing Androgen Deprivation Therapy
Status: COMPLETED
Conditions: Metastatic Prostate Cancer
Interventions: DRUG: Ga-68 PSMA ligand
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Pasireotide LAR in Severe Polycystic Liver Disease
Status: COMPLETED
Conditions: Somatostatin Analogs|Polycystic Liver Disease|Autosomal Dominant Polycystic Kidney Disease|Autosomal Dominant Polycystic Liver Disease
Interventions: DRUG: Pasireotide LAR|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Safety and Effectiveness of Levofloxacin Compared With Amoxicillin/Clavulanate Potassium in the Treatment of Adults With Rapid Onset of Severe Inflammation/Infection of the Sinuses
Status: COMPLETED
Conditions: Sinusitis|Maxillary Sinusitis
Interventions: DRUG: levofloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Definition for the Assessment of Time-to-event Endpoints in CANcer Trials (DATECAN-1)
Status: UNKNOWN
Conditions: Cancer
Interventions: OTHER: Sarcoma and GIST|OTHER: Breast cancer|OTHER: Pancreatic cancer|OTHER: Renal cell carcinoma|OTHER: Colon cancer|OTHER: Solid tumours undergoing image-guided tumor ablation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effectiveness of Two Different Methods Applied During Heel Blood Collection on Pain Level of Healthy Term Newborns
Status: COMPLETED
Conditions: Newborn|Pain|Maternal; Procedure|Needle Stick
Interventions: OTHER: Swaddling|OTHER: Maternal holding
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of the Effectiveness of Central Line Placement Using an Ultraportable Ultrasound Device
Status: NOT_YET_RECRUITING
Conditions: Medical Imaging
Interventions: OTHER: placing a standard central venous line|OTHER: placement of a central venous line using an ultraportable ultrasound device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Concomitant Radiotherapy, Tremelimumab & Durvalumab for Advanced NSCLC Patients Progressing on First-line Immunotherapy
Status: RECRUITING
Conditions: Metastatic or Locally Advanced NSCLC
Interventions: DRUG: Durvalumab|DRUG: Tremelimumab|RADIATION: Low dose irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Shi-style Cervical Manipulations for Nonspecific Neck Pain: a Multi-center, Randomized, Controlled Clinical Trial
Status: UNKNOWN
Conditions: Nonspecific Neck Pain
Interventions: OTHER: Shi-style manipulations|OTHER: Cervical Traction control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Controlled Study to Determine the Efficacy and Safety of CL-108 5 mg for Acute Pain and the Prevention of OINV
Status: COMPLETED
Conditions: Pain|Nausea|Vomiting
Interventions: DRUG: CL-108 5 mg|DRUG: Norco|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Medical Food on Reducing Asthma Symptoms in Asthmatic Children
Status: COMPLETED
Conditions: Asthma
Interventions: OTHER: medical food with EPA and GLA, vitamins and minerals|OTHER: medical food minus EPA and GLA, antioxidant vitamins/minerals
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Early Versus Late Hydration After Cesarean Section (CS)
Status: COMPLETED
Conditions: Gastrointestinal Motility and Defaecation Conditions
Interventions: OTHER: Early oral hydration|OTHER: Delayed oral hydration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: First-in-man Study of Titanium-Nitride Coated Woven-nitinol Peripheral Arterial Stent
Status: COMPLETED
Conditions: Peripheral Arterial Disease
Interventions: DEVICE: GoldenFlow Stent
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EPC Silver Wound Gel (EPC-123) Feasibility Study in the Management of Mildly Infected Diabetic Foot Ulcers
Status: COMPLETED
Conditions: Diabetic Foot Ulcer|Non-healing Diabetic Foot Ulcer|Diabetic Foot Infection
Interventions: DEVICE: EPC Silver Wound Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigating the Bioequivalence of Eptacog Alfa A 6 mg and NovoSeven® in Healthy Male Subjects
Status: WITHDRAWN
Conditions: Congenital Bleeding Disorder|Haemophilia A|Haemophilia A With Inhibitors|Haemophilia B|Haemophilia B With Inhibitors|Healthy
Interventions: DRUG: activated recombinant human factor VII|DRUG: eptacog alfa (activated)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Use of Methylone in the Treatment of PTSD
Status: RECRUITING
Conditions: Post Traumatic Stress Disorder
Interventions: DRUG: Methylone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sintilimab in Combination With Chidamide in Refractory and Relapsed AITL
Status: UNKNOWN
Conditions: Angioimmunoblastic T-cell Lymphoma
Interventions: DRUG: Sintilimab|DRUG: Chidamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dietary Nitrate on Salivary Flow for Nasopharyngeal Carcinoma Patients
Status: UNKNOWN
Conditions: Nasopharyngeal Carcinoma
Interventions: DIETARY_SUPPLEMENT: Sodium nitrate|DIETARY_SUPPLEMENT: sodium chloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Tolerability of 28 Days Treatment With Glycopyrronium Bromide (NVA237) (100 or 200 µg Once a Day) in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: DRUG: NVA237 100 µg|DRUG: Placebo|DRUG: NVA237 200 µg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dexmedetomidine in Spinal Anesthesia
Status: COMPLETED
Conditions: Blood Pressure|Anxiety
Interventions: DRUG: Dexmedetomidine|DRUG: Dexmedetomidine with heavy bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Carbon PEEK Versus Titanium Pedicle Screws in the Treatment of Spinal Tumors
Status: WITHDRAWN
Conditions: Spinal Tumor
Interventions: PROCEDURE: surgical stabilization of the spine due to primary and secondary spinal tumors
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Randomized Controlled Trial of Open Surgical vs. Minimally-invasive Voluntary Adult Male Circumcision
Status: COMPLETED
Conditions: Surgical Technique
Interventions: PROCEDURE: Gomco Clamp with Tissue Adhesive|PROCEDURE: Open surgical circumcision
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pemigatinib + Pembrolizumab vs Pemigatinib Alone vs Standard of Care for Urothelial Carcinoma (FIGHT-205)
Status: TERMINATED
Conditions: Metastatic Urothelial Carcinoma|Unresectable Urothelial Carcinoma
Interventions: DRUG: Pemigatinib|DRUG: Pembrolizumab|DRUG: Gemcitabine|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose-Ranging Study Evaluating AVE1625 in Abdominally Obese Patients With Atherogenic Dyslipidemia
Status: COMPLETED
Conditions: Obesity|Dyslipidemia
Interventions: DRUG: AVE1625 B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Vabb After Neoadjuvant Therapy to Avoid Surgery-pCR to Avoid Breast Surgery
Status: RECRUITING
Conditions: Breast Cancer|Triple Negative Breast Cancer|HER2-positive Breast Cancer|Neoadjuvant Chemotherapy
Interventions: PROCEDURE: Omission of surgical treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Arthroscopic Debridement Versus Autologous Cytokine Rich Serum for the Treatment of Lateral Epicondylitis
Status: UNKNOWN
Conditions: Epicondylitis, Lateral
Interventions: BIOLOGICAL: Autologous Cytokine Rich Serum|PROCEDURE: Arthroscopic Resection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Viability of an Educational Program for Lifestyle Changes and an Algorithm for the Derivation of Exercise Programs in Older People at Risk of Dependency at Primary Care.
Status: NOT_YET_RECRUITING
Conditions: Frailty|Disability Physical|Old Age; Atrophy
Interventions: BEHAVIORAL: EDUcation|OTHER: EXERcise|OTHER: EDU-EXER|OTHER: CONtrol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Deceased Organ Donor Interventions to Protect Kidney Graft Function
Status: COMPLETED
Conditions: Brain Death|Organ Donation|Organ Transplant Failure or Rejection|Delayed Graft Function
Interventions: OTHER: Pump Eligible - Normothermia - Pump Both Kidneys|OTHER: Pump Eligible - Hypothermia and Pump Right Kidney|OTHER: Pump Eligible - Hypothermia and Pump Left Kidney|OTHER: Not Pump Eligible - Normothermia|OTHER: Not Pump Eligible - Hypothermia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: School- and Home-Based Early Intervention for Toddlers With Autism
Status: COMPLETED
Conditions: Autistic Disorder|Autism
Interventions: BEHAVIORAL: Early intervention blending several tx approaches, w/ focus|BEHAVIORAL: Early intervention blending several treatment approaches
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Atezolizumab and Pre-Surgical Brain Radiation Therapy for Glioblastoma Multiforme
Status: RECRUITING
Conditions: Glioblastoma Multiforme
Interventions: COMBINATION_PRODUCT: Atezolizumab + FSRT radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Two Forms of Head Immobilization for Stereotactic Radiotherapy
Status: COMPLETED
Conditions: Patients Receiving Fractionated Stereotactic Radiotherapy|for Brain Tumors
Interventions: DEVICE: GTC frame|DEVICE: Thermoplastic facemask|RADIATION: Stereotactic radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tomosynthesis vs. Contrast-Enhanced Mammography in Women With Personal History of Breast Cancer in Western Pennsylvania
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer Female|Breast Cancer|Breast Neoplasms|Neoplasms
Interventions: DEVICE: Contrast-enhanced mammogram
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Cardiovascular and Renal Biomarkers to Predict Acute Heart or Kidney Injury in Severe Covid-19 Infection
Status: COMPLETED
Conditions: COVID 19
Interventions: PROCEDURE: Biological samples specific to research|PROCEDURE: Clinical examination|PROCEDURE: Telephone follow-up
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effect of High-quality Pre-operative Videos on Patient Anxiety Levels Prior to Ambulatory Hand Surgery
Status: COMPLETED
Conditions: Anxiety|Carpal Tunnel Syndrome|Trigger Finger|Engagement, Patient|Pain
Interventions: OTHER: High-quality, physician created video|OTHER: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Phase I/II Trial of ALETA-001 for the Treatment of Participants With B-cell Malignancies
Status: RECRUITING
Conditions: Lymphoma, Non-Hodgkin|Lymphoma, Large B-Cell, Diffuse|Lymphoma, Mantle-Cell|Lymphoma, Follicular|Lymphoma, B-Cell
Interventions: DRUG: ALETA-001
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT