pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Molecular-Guided Therapy for Childhood Cancer
Status: COMPLETED
Conditions: Neuroblastoma|Medulloblastoma|Glioma|Ependymoma|Choroid Plexus Neoplasms|Craniopharyngioma|Dysembryoplastic Neuroepithelial Tumor|Meningioma|Primitive Neuroectodermal Tumors (PNETs)|Germ Cell Tumors|Rhabdomyosarcoma|Non-rhabdomyosarcoma|Ewings Sarcoma|Osteosarcoma|Wilms Tumor|Renal Cell Carcinoma|Malignant Rhabdoid Tumor|Clear Cell Sarcoma|Liver Tumors
Interventions: DEVICE: Guided Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ranger Resilience and Improved Performance on Phospholipid Bound Omega-3's
Status: COMPLETED
Conditions: Nutrition|Fatty Acids, Omega-3|Cognition|Resilience, Psychological|Psychology, Military
Interventions: DIETARY_SUPPLEMENT: Phospholipid-bound omega-3 supplement|DIETARY_SUPPLEMENT: Placebo supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Low-Load Blood Flow Restriction Training vs Traditional Resistance Training Exercises Following ACLR Surgery
Status: RECRUITING
Conditions: Strength|Range of Motion|Pain-Knee|Skeletal Muscle Hypertrophy|Effusion Joint
Interventions: DEVICE: Blood Flow Restriction band|DEVICE: Non-Blood Flow Restriction band
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of E-learning on Parental Confidence in Managing Food Allergy
Status: UNKNOWN
Conditions: Food Allergy in Children|Food Allergy in Infants
Interventions: BEHAVIORAL: E-learning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Support Groups in the Metaverse for Ukrainian Refugees
Status: RECRUITING
Conditions: Mental Health Wellness 1|Well-Being, Psychological
Interventions: BEHAVIORAL: Metaverse support group|BEHAVIORAL: In-Person support group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Spiolto® Respimat® (Tiotropium/Olodaterol) Versus Triple Combination Therapy in Everyday Clinical Treatment Practice for Chronic Obstructive Pulmonary Disease (EVELUT®)
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Spiolto® Respimat®|DRUG: Triple-Therapy (LAMA/LABA/ICS)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: SEDUCE OCT Study in Coronary Artery rEstenosis:an Optical Coherence Tomography (OCT) Study
Status: COMPLETED
Conditions: Restenosis
Interventions: DEVICE: Sequent Please Paclitaxel eluting balloon|DEVICE: Xience V everolimus eluting stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anti Oxidant Enzymes and Total Antioxidant Levels in Diabetes Mellitus Type II Patients and Healthy Individuals With Periodontitis
Status: COMPLETED
Conditions: Periodontal Diseases|Diabetes Mellitus|Enzyme Disorder
Interventions: DIAGNOSTIC_TEST: Blood sample
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The SeriScaffold® Use in Reconstruction Post Market Study for Tissue Support and Repair in Breast Reconstruction Surgery in Europe
Status: COMPLETED
Conditions: Soft Tissue Support and Repair
Interventions: DEVICE: SeriScaffold® Surgical Scaffold
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Remote Ischemic Preconditioning on Moderate PVD Patients A Pilot Randomized Control Trial
Status: COMPLETED
Conditions: Peripheral Arterial Diseases
Interventions: OTHER: Remote Ischemic Preconditioning|OTHER: Supervised Exercise|OTHER: Standard Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Long-Lasting Microbial Larvicides in Reducing Malaria Transmission and Clinical Malaria Incidence
Status: COMPLETED
Conditions: Malaria
Interventions: BIOLOGICAL: Fourstar® granule, 90 day and 180 day briquettes Bti/Bs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Evaluation of an Electronic Health Record-based Screening Tool for Peripheral Artery Disease
Status: UNKNOWN
Conditions: Peripheral Artery Disease|Peripheral Vascular Disease
Interventions: OTHER: High PAD risk Alert
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Establishment and Clinical Application of Precise SLNB System in Breast Cancer: a Randomized, Multicenter, Controlled Study
Status: RECRUITING
Conditions: Breast Cancer
Interventions: PROCEDURE: Participants receive SLNB as well as non SLNs resection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison Study of Oxytocin Versus Tranexamic Acid and Etamsylaye Versus Placebo(Saline)
Status: COMPLETED
Conditions: Blood Loss, Surgical|Blood Loss, Postoperative
Interventions: DRUG: Oxytocin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Collaborative Care Program to Improve Depression Treatment in Cardiac Patients
Status: COMPLETED
Conditions: Coronary Artery Disease|Congestive Heart Failure|Arrhythmia|Depression
Interventions: BEHAVIORAL: Collaborative Care Treatment|BEHAVIORAL: Usual Care Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Single Period Investigation to Assess the Tolerability of Healthy Subjects to Oral Sinemet® (Levodopa/Carbidopa)
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DRUG: Levodopa/Carbidopa (Sinemet)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Assess the Effect of Erythromycin on the Rate of Success in Placement of a Self-propelled Feeding Tube
Status: COMPLETED
Conditions: Pancreatitis
Interventions: DRUG: Erythromycin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Relative Bioavailability Three New Formulations of Telaprevir in Healthy Subjects
Status: COMPLETED
Conditions: Chronic Hepatitis C
Interventions: DRUG: telaprevir formulation A|DRUG: telaprevir Formulation B|DRUG: telaprevir Formulation C|DRUG: telaprevir Formulation D
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Combination Chemotherapy Followed by Chemotherapy and Radiation Therapy and/or Surgery in Treating Patients Who Have Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DRUG: cisplatin|DRUG: gemcitabine hydrochloride|PROCEDURE: surgical procedure|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Safety of ToleroMune House Dust Mite (HDM) to Treat House Dust Mite Allergy in HDM Allergic Subjects With Rhinoconjunctivitis
Status: COMPLETED
Conditions: Allergy
Interventions: BIOLOGICAL: Toleromune HDM|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Low Salicylate Diet in Aspirin Exacerbated Respiratory Disease
Status: UNKNOWN
Conditions: Aspirin Exacerbated Respiratory Disease|Samter's Triad
Interventions: BEHAVIORAL: Low salicylate diet|BEHAVIORAL: Normal diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Divalproex Sodium (Depakote) in Treating Children With Temper Outbursts and Severe Mood Swings
Status: COMPLETED
Conditions: Mood Disorders
Interventions: DRUG: Divalproex Sodium (Depakote)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Masitinib in Combination With Methotrexate, in Treatment of Patients With Active Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: masitinib|DRUG: masitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Hyperoncotic Albumin on Vascular Hemodynamics and Oxygen Delivery Following Orthotopic Liver Transplant
Status: UNKNOWN
Conditions: Other Complications of Liver Transplant
Interventions: DRUG: Saline|DRUG: 25% albumin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Antiplatelet Effects of Different Dosages of Aspirin in Type 2 Diabetic Patients
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Aspirin|DRUG: aspirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Study of CM326 in Moderate-to-severe Atopic Dermatitis
Status: RECRUITING
Conditions: Moderate-to-severe Atopic Dermatitis
Interventions: BIOLOGICAL: CM326|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of General Anesthesia and Spinal-Morphine Anesthesia on Recovery and Comfort After Benign Abdominal Hysterectomy
Status: COMPLETED
Conditions: Hysterectomy (MeSH nr: E04.950.300.399)
Interventions: DRUG: Bupivacain|DRUG: Morphine|DRUG: Propofol|DRUG: Propofol|DRUG: Fentanyl|DRUG: Rocuronbromid|DRUG: Morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Efficacy of Manual Therapy and Pressure Biofeedback Guided Strength Training on Pain and Functional Limitations
Status: COMPLETED
Conditions: Cervicogenic Headache
Interventions: OTHER: Pressure biofeedback guided DCFM strength training|OTHER: Manual therapy|OTHER: Conventional intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Preoperative Anxiety and Postoperative Pain in Children
Status: UNKNOWN
Conditions: Post-Operative Pain|Pre-Operative Anxiety
Interventions: PROCEDURE: Transcutaneous iliohypogastric|PROCEDURE: Perioperative administration near the nerve
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Impact of Kinesiophobia on Descending Corticospinal and Bulbospinal Projections
Status: COMPLETED
Conditions: Kinesiophobia
Interventions: BEHAVIORAL: Nocebo|BEHAVIORAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Anti-Inflammatory Challenge in Schizophrenia
Status: RECRUITING
Conditions: Schizophrenia
Interventions: DRUG: Infliximab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Molecular Imaging to Capture Disease Heterogeneity in Acute Myeloid Leukemia
Status: UNKNOWN
Conditions: Leukemia, Myeloid, Acute
Interventions: PROCEDURE: FDG-PET/CT guided bone marrow sampling
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: TMC114-C213: A Phase II Randomized, Controlled, Partially Blinded Trial to Investigate Dose-response of TMC114/RTV in 3-class-experienced HIV-1 Infected Patients, Followed by an Open-label Period on the Recommended Dose of TMC114/RTV.
Status: COMPLETED
Conditions: HIV
Interventions: DRUG: TMC114; darunavir; Prezista
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Prevention of Radial Artery Occlusion After Transradial Access Using Nitroglycerin
Status: UNKNOWN
Conditions: Injury of Radial Artery
Interventions: DRUG: Nitroglycerin I|DRUG: Placebo I|DRUG: Nitroglycerin II|DRUG: Placebo II
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Using Biomarkers to Predict TB Treatment Duration
Status: COMPLETED
Conditions: Pulmonary Tuberculosis
Interventions: PROCEDURE: Saliva collection|PROCEDURE: Urine collection|PROCEDURE: Sputum collection|PROCEDURE: Blood Collection|RADIATION: PET/CT Scan|DRUG: Isoniazid, Rifampicin, Pyrazinamide and Ethambutol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Songling Xuemaikang Capsules on Grade 1 Hypertension: a Randomized Controlled Trial
Status: RECRUITING
Conditions: Hypertension,Essential
Interventions: DRUG: Songling Xuemaikang Capsules|BEHAVIORAL: Lifestyle intervention|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Response of the Airway in Sinusitis and Asthma
Status: COMPLETED
Conditions: Sinusitis|Asthma
Interventions: DRUG: Mometasone Nasal|DRUG: placebo mometasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Opioid Free Versus Opioid-Based Anesthesia on Cerebral Oximetry In Gastric Sleeve Operation
Status: UNKNOWN
Conditions: Bariatric Surgery Candidate
Interventions: OTHER: induction of anesthesia|OTHER: maintainance of anesthesia|OTHER: monitoring|OTHER: First postoperative analgesia|OTHER: Second postoperative analgesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Randomized Trial Comparing PrePex Day 7 Foreskin Removal Procedure (FRP) to a Day 0 PrePex FRP .
Status: COMPLETED
Conditions: Male Circumcision
Interventions: DEVICE: PrePex Day 7 FRP|DEVICE: PrePex Day 0 FRP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Assess Efficacy & Safety of Selumetinib in Combination With Docetaxel in Patients Receiving 2nd Line Treatment for v-Ki-ras2 Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) Positive NSCLC
Status: ACTIVE_NOT_RECRUITING
Conditions: Locally Advanced or Metastatic Non Small Cell Lung Cancer Stage IIIb - IV
Interventions: DRUG: Selumetinib|DRUG: Docetaxel|DRUG: Placebo|DRUG: Pegylated G-CSF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Concentration of Antimicrobials in Catheter-lock Solutions
Status: UNKNOWN
Conditions: Catheter-Related Infections|Bacteremia.
Interventions: DRUG: Vancomycin antimicrobial-lock solution|DRUG: Teicoplanin antimicrobial-lock solution|DRUG: Linezolid antimicrobial-lock solution|DRUG: Daptomycin antimicrobial-lock solution|DRUG: Tigecycline antimicrobial-lock solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Appropriate Gestational Weight Gain in Overweight/Obese Women
Status: COMPLETED
Conditions: Gestational Weight Gain
Interventions: BEHAVIORAL: Lifestyle Intervention|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: CLCF1 Gene Associated With Postmenopausal Osteoporosis of Kidney Yin Deficiency Syndrome
Status: UNKNOWN
Conditions: Postmenopausal Osteoporosis
Interventions: OTHER: Liuwei Dihuang Pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of High Dose CoQ10 in ALS
Status: COMPLETED
Conditions: Amyotrophic Lateral Sclerosis|Lou Gehrig's Disease
Interventions: DRUG: coenzyme Q10|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Acupuncture for Post-Thoracotomy Pain
Status: COMPLETED
Conditions: Lung Cancer|Pain
Interventions: PROCEDURE: Acupuncture and Questionnaires|PROCEDURE: Placebo Acupuncture, Questionnaires
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Acute ACL Injuries in Young Patients Using a Rebound ACL Brace
Status: RECRUITING
Conditions: Anterior Cruciate Ligament Injuries|Anterior Cruciate Ligament Rupture|Anterior Cruciate Ligament Tear
Interventions: OTHER: Rebound ACL brace and physioterapy|OTHER: Physioterapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Docetaxel, Carboplatin, and Bevacizumab in Treating Patients With Stage I, Stage II, or Stage III Non-Small Cell Lung Cancer That Can Be Removed By Surgery
Status: TERMINATED
Conditions: Lung Cancer
Interventions: BIOLOGICAL: bevacizumab|DRUG: carboplatin|DRUG: docetaxel|PROCEDURE: conventional surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Women With an Early Diagnosis of Breast Cancer, Taking Celecoxib Between the Biopsy and Lumpectomy/Mastectomy
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: celecoxib 400 mg bid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: A Comparison Of The Pharmacokinetics Of PF-04191834 Following Single Dose Administration Of A Dispersion Formulation And A Suspension Formulation In Healthy Volunteers
Status: WITHDRAWN
Conditions: Healthy
Interventions: DRUG: PF-04191834|DRUG: PF-04191834|DRUG: PF-04191834
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Two Techniques of Mobilization in the Dorsiflexion on Patients With Chronic Ankle Instability
Status: COMPLETED
Conditions: Chronic Instability of Joint
Interventions: OTHER: HVLA|OTHER: MWM|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Analysis of Stem and Non-Stem Tibial Component
Status: RECRUITING
Conditions: Obesity|Aseptic Loosening|Varus Collapse
Interventions: PROCEDURE: Total Knee Arthroplasty (TKA)|DEVICE: Stemmed Tibial Implant|DEVICE: Non-stemmed tibial implant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Video-based Multicomponent Treatment for Fibromyalgia Plus Face-to-face Sesions in Nature or at Sea
Status: UNKNOWN
Conditions: Fibromyalgia
Interventions: BEHAVIORAL: TAU + multicomponent treatment VIRTUAL FIBROWALK + 4 face-to-face sessions at sea|BEHAVIORAL: TAU + multicomponent treatment VIRTUAL FIBROWALK + 4 face-to-face sessions in nature|BEHAVIORAL: TAU + multicomponent treatment VIRTUAL FIBROWALK
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Circulating Tumor DNA Exposure in Peripheral Blood
Status: UNKNOWN
Conditions: Colorectal Cancer|Pancreatic Adenocarcinoma|Gastric Cancer|Hepatocellular Carcinoma|Non-small Cell Lung Cancer|Bladder Cancer|Melanoma|Ovarian Cancer|Adrenocortical Cancer|Breast Cancer|Other Cancer
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy of Esmolol Versus Magnesium Sulphate on Quality of Recovery in Patients Undergoing Laparoscopic Cholecystectomy: Randomized Controlled Study
Status: COMPLETED
Conditions: Esmolol Adverse Reaction
Interventions: DRUG: Esmolol|DRUG: Magnesium sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Targeted Multidomain (T-MD) Interventions for Complex Mild Traumatic Brain Injury (mTBI)
Status: ACTIVE_NOT_RECRUITING
Conditions: Concussion, Mild
Interventions: BEHAVIORAL: Targeted Multidomain|BEHAVIORAL: Behavioral Management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Safety and Treatment in Subjects With Osteoarthritis Taking Low Dose Aspirin
Status: COMPLETED
Conditions: Osteoarthritis|Peptic Ulcer
Interventions: DRUG: Lansoprazole and naproxen and aspirin|DRUG: Celecoxib and aspirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MagicTouch Sirolimus Drug Coated Balloon Catheter for the Treatment of Coronary Lesions
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DEVICE: MAGIC-TOUCH Drug-eluting Balloon
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exercise and Pharmacotherapy for Anxiety in Cardiac Patients
Status: COMPLETED
Conditions: Anxiety|Cardiovascular Disease
Interventions: DRUG: Lexapro|DRUG: Placebo|BEHAVIORAL: Supervised Aerobic Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Explore the Effective Doses and to Assess the Safety and Efficacy of Hypidone Hydrochloride Tablets
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: Hypidone Hydrochloride tablets|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Early Follicular Phase vs Lutheal Phase Ovarian Stimulation in Bologna Criteria IVF/ICSI Cycles (LUTEAL Trial)
Status: UNKNOWN
Conditions: Reproductive Techniques, Assisted
Interventions: PROCEDURE: Follicular phase|PROCEDURE: Luteal phase
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Pharmacokinetics and Pharmacodynamics of BKM120 Plus MEK162 in Selected Advanced Solid Tumor Patients
Status: COMPLETED
Conditions: Advanced Solid Tumors|Selected Solid Tumors
Interventions: DRUG: BKM120 + MEK162
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Well-child Clinics as the "Community" Basis of Step 10 of the Baby Friendly Hospital Initiative
Status: COMPLETED
Conditions: Breastfeeding
Interventions: OTHER: implementation of the Baby-Friendly Hospital Initiative|OTHER: BFHI steps 1-9 +well-child clinic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: PIO Laser Sclerectomy IOP SLT Sclerectomy
Status: COMPLETED
Conditions: Primary Open-Angle Glaucoma
Interventions: PROCEDURE: Selective Laser Trabeculoplasty (Tango Laser, Ellex)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ketogenic Diet & Functional Recovery in Moderate to Severe Traumatic Brain Injury
Status: ENROLLING_BY_INVITATION
Conditions: Traumatic Brain Injury
Interventions: OTHER: ketogenic/modified Atkins diet|OTHER: Standard diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Controlling Femoral Derotation Osteotomy With Electromagnetic Tracking
Status: UNKNOWN
Conditions: Interna Rotation Gait|Cerebral Palsy|Malrotation; Bone|In-toing
Interventions: OTHER: Electromagnetic tracking unit in femoral derotation surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Ginger's Therapeutic Potential in Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Ginger Extract|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: HAIC Combined With Donafenib Tosilate and Toripalimab for Unresectable HCC
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma
Interventions: PROCEDURE: HAIC(FOLFOX)|DRUG: Oxaliplatin|DRUG: Leucovorin|DRUG: Fluorouracil|DRUG: Toripalimab|DRUG: Donafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Decreasing Loneliness to Optimize Pain Care
Status: ENROLLING_BY_INVITATION
Conditions: Loneliness|Opioid Use
Interventions: BEHAVIORAL: Cognitive Behavior Therapy (CBT)|BEHAVIORAL: Social Navigation Group|BEHAVIORAL: Controlled Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Proof-of-concept Study to Evaluate the Safety and Efficacy of Tryptophan in Patients With BPH.
Status: UNKNOWN
Conditions: BPH
Interventions: DRUG: Tamsulosin|DRUG: 5-hidroxitriptophan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immunomodulating Nutrients in Perioperative Patients With Gastric Cancer
Status: COMPLETED
Conditions: Gastric Cancer
Interventions: DIETARY_SUPPLEMENT: immunomodulating nutrients enriched diet|DIETARY_SUPPLEMENT: standard diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Computer-Mediated Intervention to Enhance Emotional Competence in Children With Autism in Schools
Status: ACTIVE_NOT_RECRUITING
Conditions: Autism Spectrum Disorder|Intellectual Disability, Mild
Interventions: BEHAVIORAL: EmotiPlay
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: HIV Counseling and Testing and Linkage to Care in Uganda
Status: COMPLETED
Conditions: HIV Infections
Interventions: BEHAVIORAL: Voluntary brief HIV counseling and testing|BEHAVIORAL: Voluntary longer, more detailed HIV counseling and testing|BEHAVIORAL: Enhanced linkage to care|BEHAVIORAL: Routine referral to care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison Between Amoxycillin/Clavulanic Acid and Oxacillin/Ceftriaxone for Community Acquired-pneumonia
Status: COMPLETED
Conditions: Community-Acquired Pneumonia
Interventions: DRUG: Amoxycillin/clavulanic acid|DRUG: ceftriaxone/oxacillin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Carbon Dioxide Insufflation Colonoscopy in IBD Patients
Status: COMPLETED
Conditions: Colonoscopy|Carbon Dioxide|Inflammatory Bowel Disease
Interventions: PROCEDURE: Carbon dioxide insufflation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Effectiveness of Interprofessional Mentoring Competence Education for Dental Health Care Professionals
Status: UNKNOWN
Conditions: Competence
Interventions: OTHER: Blended learning approach to mentoring education for dental health care professionals|OTHER: The interprofessional online mentoring education
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Clinical Study of the Effectiveness, Tolerability and Safety of the Drug "Anti-spike, Gel, 100 g in Bottles in Package No. 1" Produced by the Republican Unitary Enterprise "Unitekhprom BSU", With a Single Intraperitoneal Use After Surgery in Adult Patients With Acute Phlegmonous Appendicitis
Status: NOT_YET_RECRUITING
Conditions: Abdominal Adhesions
Interventions: DRUG: Antispike gel, 100 g in a flask, produced by UNITEHPROM BSU, Republic of Belarus|PROCEDURE: antegrade appendectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effectiveness of Hysteroscopy in the Treatment of Intrauterine Trophoblastic Retentions
Status: COMPLETED
Conditions: Incomplete Miscarriage
Interventions: PROCEDURE: Hysteroscopy|PROCEDURE: Curettage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial In Healthy Volunteers And Health Elderly Volunteers To Evaluate The Safety, Tolerability And Blood Concentration After Single And Multiple Escalating Oral Doses Of PF-06751979.
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: PF-06751979 single dose|DRUG: Placebo single dose|DRUG: PF-06751979 multiple ascending dose|DRUG: Placebo multiple ascending dose|DRUG: PF-06751979 multiple dose|DRUG: Placebo multiple elderly dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Point of Care Testing for Presence of Current and or Previous T. Gondii Infection
Status: ACTIVE_NOT_RECRUITING
Conditions: Toxoplasma Infections
Interventions: DEVICE: toxoplasma ICT IgG-IgM BK
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy and Safety of the Cryopreserved Formulation of OTL-101 in Subjects With ADA-SCID
Status: COMPLETED
Conditions: Severe Combined Immunodeficiency Due to ADA Deficiency
Interventions: GENETIC: Infusion of autologous cryopreserved EFS-ADA LV CD34+ cells (OTL-101)|DRUG: Busulfan|DRUG: Peg-Ada
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Groceries for Black Residents of Boston to Stop Hypertension Among Adults With Treated Hypertension
Status: RECRUITING
Conditions: Hypertension
Interventions: BEHAVIORAL: Dietitian-Assisted DASH groceries|BEHAVIORAL: Self-directed shopping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Sodium Zirconium Cyclosilicate on Arrythmia-related Cardiovascular Outcomes in Participants on Chronic Hemodialysis With Recurrent Hyperkalemia (DIALIZE-Outcomes)
Status: TERMINATED
Conditions: Hyperkalemia
Interventions: DRUG: Sodium Zirconium Cyclosilicate (SZC)|DRUG: SZC Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Results of Odyliresin (Iresine Celosia) in Symptomatic Benign Prostatic Hyperplasia
Status: COMPLETED
Conditions: Benign Prostatic Hypertrophy With Outflow Obstruction|Benign Prostatic Hyperplasia
Interventions: DIETARY_SUPPLEMENT: Odyliresin|DRUG: Alfuzosin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: VNRX-5133 Drug-Drug Interaction in Healthy Adult Volunteers
Status: COMPLETED
Conditions: Bacterial Infections
Interventions: DRUG: VNRX-5133|DRUG: VNRX-5022|DRUG: Metronidazole|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: New Investigational Stimulation Protocol for Treatment of Major Depression Disorder (MDD)
Status: RECRUITING
Conditions: Major Depressive Disorder
Interventions: DEVICE: Brainsway Deep TMS System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SOLEMN Study - Synergy Optical Coherence Tomography in Left Main PCI
Status: TERMINATED
Conditions: Percutaneous Coronary Intervention|Optical Coherence Tomography|In-stent Coronary Artery Restenosis
Interventions: DEVICE: Optical Coherence Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Prospective Study of the Phenotypic Expression of Cystic Fibrosis (CF) Screened Positive Newborns With an Atypical Form of CF (DPAM)
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: RADIATION: Lung CT scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Changes in Muscle Strength, Inflammatory Markers, and Body Composition in Response to Alternate Day Fasting Combined With Krill Oil Supplementation in Adults With Overweight and Obesity
Status: RECRUITING
Conditions: Obesity Associated Disorder
Interventions: DIETARY_SUPPLEMENT: krill oil (SuperbaBoostTM)|DIETARY_SUPPLEMENT: 4g/day of mixed vegetable oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Psilocybin in the Treatment of Cannabis Use Disorder: A-Proof-of-Concept Study
Status: NOT_YET_RECRUITING
Conditions: Cannabis Use Disorder, Moderate|Cannabis Use Disorder, Severe
Interventions: DRUG: Psilocybin combined with Psychotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tele-rehabilitation Group Program for Urinary Incontinence in Older Women
Status: ACTIVE_NOT_RECRUITING
Conditions: Urinary Incontinence|Urinary Stress Incontinence
Interventions: BEHAVIORAL: Group pelvic floor telerehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Behavioral Activation for PTSD/Depression Treatment in OIF/OEF Veterans
Status: COMPLETED
Conditions: Posttraumatic Stress Disorder|Depression
Interventions: BEHAVIORAL: Behavioral Activation treatment|OTHER: Treatment as Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Serum Creatinine Change / Renal Adverse Effect With Use of Non-steroidal Painkillers in Axial Spondyloarthritis Patients
Status: COMPLETED
Conditions: Axial Spondyloarthritis
Interventions: DRUG: Indomethacin SR, 75 Mg Oral Capsule, Extended Release|DRUG: Indomethacin 25 Mg Oral Capsule|DRUG: Etoricoxib 90 mg|DRUG: Etoricoxib 60 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Screening, Brief Intervention, and Referral to Treatment in Primary Care
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Substance-related Disorders
Interventions: BEHAVIORAL: Referral to Treatment|BEHAVIORAL: Brief Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Effects of tDCS and TUS on the Perception of Pain and Functional Limitations Due to Non-Specific Chronic Low Back Pain
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Pain|Chronic Low Back Pain
Interventions: DEVICE: transcranial Direct Current Stimulation (tDCS)|DEVICE: Transcranial Ultrasound (TUS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Double-Blind Treatment of Major Depressive Disorder With Vilazodone
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: Vilazodone|DRUG: Citalopram
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Lidocaine Prilocaine Cream and Lidocaine Injection on Pain Control During Episiotomy.
Status: ACTIVE_NOT_RECRUITING
Conditions: Episiotomy Wound
Interventions: DRUG: 10 ml of lidocaine 2%|DRUG: lidocaine prilocaine cream 15gm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Radiographic Progression of Sealed and Infiltrated Caries Lesions in Vivo
Status: COMPLETED
Conditions: Dental Caries
Interventions: DRUG: Resin infiltration / adhesive|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Is Synchronization More Effective During Noninvasive Ventilation in Immediately Extubated Preterm Infants?
Status: UNKNOWN
Conditions: Respiratory Distress Syndrome
Interventions: DEVICE: S-nIMV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Cap Assisted Colonoscopy for the Detection of Colon Polyps
Status: UNKNOWN
Conditions: Adenoma|Colon Polyps|Colon Cancer
Interventions: DEVICE: Cap - Transparent retractable extension device.|DEVICE: Standard
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Drug-eluting Stenting Versus Medical Treatment for Extracranial Vertebral Artery Stenosis
Status: RECRUITING
Conditions: Ischemic Stroke|Vertebral Artery Stenosis
Interventions: PROCEDURE: Drug-eluting stenting plus aspirin and clopidogrel or ticagrelor|DRUG: Aspirin and clopidogrel or ticagrelor|PROCEDURE: mono anti-platelet therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pre-Visit Prioritization for Complex Patients With Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: BEHAVIORAL: Pre-Visit Tool|BEHAVIORAL: Usual Care Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: GAMEC-II, Risk-adapted Protocol for Relapsed Germ Cell Tumours (GCT)
Status: COMPLETED
Conditions: Testicular Neoplasms
Interventions: DRUG: Pegfilgrastim|DRUG: Dactinomycin|DRUG: Methotrexate|DRUG: Etoposide|DRUG: Cisplatin|DRUG: Epirubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioavailability of Medium Chain Triglycerides (MCTs) in Comatose Patients With Acute Brain Injury (ABI)
Status: COMPLETED
Conditions: Injuries, Acute Brain|Severe Trauma Brain Injury (sTBI)|Subarachnoid Hemorrhage, Aneurysmal
Interventions: DIETARY_SUPPLEMENT: Peptamen AF
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Interleukin-15 Armored Glypican 3-specific Chimeric Antigen Receptor Expressed in T Cells for Pediatric Solid Tumors
Status: RECRUITING
Conditions: Liver Cancer|Rhabdomyosarcoma|Malignant Rhabdoid Tumor|Liposarcoma|Wilms Tumor|Yolk Sac Tumor
Interventions: GENETIC: AGAR T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of a Positive Expiratory Pressure (PEP) on Dyspnea and Dynamic Hyperinflation During Exercise in Chronic Obstructive Pulmonary Disease (COPD) Patients
Status: UNKNOWN
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DEVICE: Conical Positive Expiratory Pressure Device (C-PEP)|OTHER: Control breathing
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Assess the Effect of a 3-month Folate Supplementation on Systemic Homocysteine Plasma Concentration and Ocular Blood Flow in Patients With Diabetes
Status: COMPLETED
Conditions: Diabetes
Interventions: DIETARY_SUPPLEMENT: Ocufolin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Acoustic and Perceptual Effects of Intonation Training in Gender Diverse People
Status: RECRUITING
Conditions: Gender Dysphoria
Interventions: OTHER: Intonation training|OTHER: Sham therapy + intonation training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Association of Real-world Sensor-derived Biometric Data With Clinical Parameters and Patient-reported Outcomes for Monitoring Disease Activity in Patients With COPD
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DEVICE: Vivalink wearable device
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Acupuncture to Prevent Chemotherapy Dose Reduction Due to Chemotherapy-induced Peripheral Neuropathy in Breast and Colorectal Cancer Patients (GCC1232)
Status: TERMINATED
Conditions: Breast Cancer|Colorectal Cancer
Interventions: DEVICE: Acupuncture using Seirin® needles|DEVICE: Sham Acupuncture using Park Sham placebo acupuncture device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Clinical Validation of Medasense Pain Response Index (PRI)
Status: COMPLETED
Conditions: Surgery|Pain
Interventions: DRUG: Base level of remifentanil effect side concentration: 2ng/ml|DRUG: Base level of remifentanil effect side concentration: 4ng/ml|OTHER: chronic beta-blocker treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SCREENING
Clinical trial: Pharmacokinetic Study of ADVATE 3000 IU in Previously Treated Patients With Severe Hemophilia A
Status: COMPLETED
Conditions: Hemophilia A
Interventions: BIOLOGICAL: Octocog alfa (recombinant human coagulation factor VIII) [ADVATE]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Minimal Invasive Transforaminal Lumbar Interbody Fusion for Degenerative Lumbar and Lumbosacral Spine Diseases
Status: NOT_YET_RECRUITING
Conditions: Degenerative Spine Diseases
Interventions: PROCEDURE: lumbar fusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The ASCEND Study: Evaluating TMB-001 in the Treatment of RXLI or ARCI Ichthyosis
Status: ACTIVE_NOT_RECRUITING
Conditions: Ichthyosis
Interventions: DRUG: TMB-001|DRUG: Matching Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pre Injection Use of Cryoanesthesia Versus Topical Anesthetic Gel in Reducing Pain Perception During Palatal Injections
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Topical Benzocaine|OTHER: Topical ice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Sentinel Lymph Node Sampling for Patients With Middle-high Risk Endometrial Cancer Confined to the Uterus
Status: RECRUITING
Conditions: Middle-high Risk Endometrial Cancer|Sentinel Lymph Node Sampling|Prognosis
Interventions: PROCEDURE: sentinel lymph node sampling (SLN)|PROCEDURE: pelvic lymphonodectomy (PLN)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Low-intensity Shockwave Therapy Versus Kegel Exercises on Arteriogenic Erectile Dysfunction in DM Patients
Status: RECRUITING
Conditions: Sexual Dysfunction|Shock Wave
Interventions: DEVICE: Low-intensity Shockwave Therapy|OTHER: Kegel Exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT