pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Phase 2 Study of MP-376 to Prevent Acute Exacerbations in Chronic Obstructive Pulmonary Disease (COPD) Patients
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: MP-376|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy Followed by Peripheral Stem Cell Transplantation And Biological Therapy in Treating Patients With Chronic Myelogenous Leukemia
Status: COMPLETED
Conditions: Leukemia
Interventions: BIOLOGICAL: aldesleukin|BIOLOGICAL: recombinant interferon alfa|BIOLOGICAL: sargramostim|DRUG: busulfan|PROCEDURE: peripheral blood stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Impact of Breast Shield Designs on Dynamics of Breast Pumping
Status: COMPLETED
Conditions: Lactation
Interventions: DEVICE: Soft edge oval - Hard oval - Modified PF breast shield|DEVICE: Modified PF breast shield - Soft edge oval - Hard oval|DEVICE: Hard oval - Soft edge oval - Modified PF breast shield
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Obesity, Iron Regulation and Colorectal Cancer Risk
Status: COMPLETED
Conditions: Colon Inflammation|Iron Malabsorption|Obesity|Diet Modification
Interventions: OTHER: High heme iron diet|OTHER: Low iron diet|OTHER: Plant-based high non-heme iron diet
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Comparison of Anesthesia Type in Patients Undergoing Transabdominal Cervico Isthmic Cerclage (TCIC)
Status: TERMINATED
Conditions: Cervical Incompetence
Interventions: DRUG: Bupivacaine Hcl 0.5% Inj|DRUG: Propofol 10 milligram/ML
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Telithromycin: in the Treatment of Acute Exacerbation of Chronic Bronchitis in Adult Outpatients With COPD
Status: COMPLETED
Conditions: Bronchitis, Chronic
Interventions: DRUG: Telithromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study in Healthy Subjects to Determine the Effect of an Inhibitor on Exposure to Relacorilant and Its Metabolites
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Relacorilant 350mg|DRUG: Itraconazole|DRUG: Relacorilant 300mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Efficacy and Safety of CKD516 Combined With Durvalumab in Patient Refractory Solid Tumors
Status: TERMINATED
Conditions: Colorectal Cancer|Solid Tumor
Interventions: DRUG: CKD-516 plus Durvalumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact in Quality of Care of the "STructural heARt NURSE" as New Interventional Cardiology Nursing Role in Spain.
Status: UNKNOWN
Conditions: Valvular Heart Disease|Nurse's Role|Competence|Cardiac Disease
Interventions: OTHER: STAR Nurse|OTHER: Common Practice
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Comparison of Articaine Mandibular Infiltration to Lidocaine Inferior Alveolar Nerve Block in Pediatric Patients
Status: TERMINATED
Conditions: Anesthesia
Interventions: PROCEDURE: Dental local anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of Efficacy and Safety of Repaglinide Combined With Insulin NPH Versus Biphasic Human Insulin 30 Alone in Inadequately Controlled Subjects With Type 2 Diabetes
Status: TERMINATED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: repaglinide|DRUG: biphasic human insulin 30|DRUG: insulin NPH
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High Frequency Oscillatory Ventilation Versus High Frequency Jet Ventilation for Congenital Diaphragmatic Hernia
Status: RECRUITING
Conditions: Congenital Diaphragmatic Hernia
Interventions: DEVICE: High Frequency Jet Ventilator|DEVICE: High Frequency Oscillatory Ventilator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GLP-1 on Non-ST-Segment Elevation Myocardial Infarction
Status: UNKNOWN
Conditions: Myocardial Infarction
Interventions: DRUG: GLP-1|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pembrolizumab And Lenvatinib In Leptomeningeal Metastases
Status: TERMINATED
Conditions: Solid Tumor|Solid Tumor, Adult|Leptomeningeal Metastasis
Interventions: DRUG: Pembrolizumab|DRUG: Lenvatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Two Different Doses of Dexmedetomidine Infusion in Morbidly Obese Patients
Status: COMPLETED
Conditions: Anesthesia|Obesity, Morbid|Dexmedetomidine
Interventions: DRUG: Dexmedetomidine 0.6|DRUG: Dexmedetomidine 0.3|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Surgical Management of Spinal Cord Injuries In Neck
Status: UNKNOWN
Conditions: Central Cord Syndrome|Spinal Cord Injury|Quadriparesis
Interventions: PROCEDURE: Early and late surgery for traumatic central cord syndrome
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment for Cannabis Withdrawal and Dependence
Status: COMPLETED
Conditions: Cannabis Dependence
Interventions: DRUG: Aprepitant|DRUG: Placebo|BEHAVIORAL: Manual-guided behavioral counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Muscle Coactivation Strengthening for Rotator Cuff Tendinopathy
Status: COMPLETED
Conditions: Tendinopathy
Interventions: PROCEDURE: Coactivation Strengthening|PROCEDURE: Regular Strengthening
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Strawberries and Disease Risk
Status: COMPLETED
Conditions: Nutritional and Metabolic Diseases|Inflammation|Physiological Responses
Interventions: DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: 10G|DIETARY_SUPPLEMENT: 20G|DIETARY_SUPPLEMENT: 40G|DIETARY_SUPPLEMENT: Placebonofiber
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pilates Exercises and Soccer: A Comparative Study of Mat vs. Reformer on FMS and ROM
Status: COMPLETED
Conditions: Sports, Mechanical
Interventions: OTHER: Reformer pilates|OTHER: Mat Pilates
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Methotrexate in the Treatment of Advanced Knee Osteoarthritis With Effusion-synovitis
Status: COMPLETED
Conditions: Knee Osteoarthritis|Effusion Synovial|Knee Pain
Interventions: DRUG: Methotrexate|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Tocilizumab in the Treatment of Generalized Myasthenia Gravis
Status: RECRUITING
Conditions: Myasthenia Gravis, Generalized
Interventions: DRUG: Tocilizumab Injectable Product
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Promoting Recovery After STroke With Amantadine
Status: RECRUITING
Conditions: Stroke, Ischemic|Stroke Hemorrhagic
Interventions: DRUG: Amantadine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of a Vaccine Against Enterotoxigenic Escherichia Coli (ETEC) to Prevent Moderate to Severe Diarrhea
Status: COMPLETED
Conditions: Diarrhea
Interventions: BIOLOGICAL: ACE527|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Increasing Food Literacy in Preschoolers to Reduce Obesity Risk
Status: RECRUITING
Conditions: Food Preferences|Food Selection|Eating, Healthy|Obesity, Childhood
Interventions: BEHAVIORAL: Healthy Eating Curriculum|BEHAVIORAL: Improving the Classroom Food and Mealtime Environment|BEHAVIORAL: Parent Education|BEHAVIORAL: ECE Food Acceptance Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Prevention and Control of Neoplasms Associated With HPV in High-risk Groups in Mexico City: The Condesa Study
Status: COMPLETED
Conditions: Cancer of Cervix
Interventions: BIOLOGICAL: Gardasil® [Quadrivalent Human Papillomavirus (Types 6,11,16,18) Recombinant vaccine]|BIOLOGICAL: Two dose|OTHER: Control group|BIOLOGICAL: 2 dose vaccination over 6 month
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Comparative Effectiveness of Hybrid Revascularization (MIDCAB Then PCI) With DES Versus Multivessel DES PCI or CABG
Status: COMPLETED
Conditions: Coronary Artery Disease|Myocardial Ischemia|Coronary Disease|Heart Diseases
Interventions: PROCEDURE: Hybrid (MIDCAB+PCI)|PROCEDURE: PCI|PROCEDURE: CABG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: First-in-man Study of Single and Multiple Ascending Doses of a New Drug for Neurological Disorders
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: AC-082|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Vascular Lab Resource (VLR) Biorepository
Status: RECRUITING
Conditions: Cardiovascular Diseases|Metabolic Disease|Peripheral Artery Disease|Carotid Disease|Aneurysmal Disease|Venous Disease|Thrombosis|Lymphedema|Lipedema|Non-Atherosclerotic Chronic Arterial Occlusive Disease|Vasculitis|Fibromuscular Dysplasia|Arterial Dissection|May-Thurner Syndrome|Thoracic Outlet Syndrome|Vasospasm
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: This is a Double-blind, Placebo-controlled, Randomized Study of the Tolerability, Safety and Immunogenicity of an Inactivated Whole Virion Concentrated Purified Vaccine (CoviVac) Against Covid-19
Status: COMPLETED
Conditions: Coronavirus Infections|Vaccine
Interventions: BIOLOGICAL: Vaccine for intramuscular injection|OTHER: Placebo comparator (without active ingredient) for intramuscular injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Does AI-assisted Colonoscopy Improve Adenoma Detection in Screening Colonoscopy?
Status: UNKNOWN
Conditions: Screening Colonoscopy
Interventions: PROCEDURE: AI-assisted Colonoscopy|PROCEDURE: Standard Colonoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of LY3298176 (Tirzepatide) For the Maintenance of Body Weight Reduction in Participants Who Have Obesity or Overweight With Weight-Related Comorbidities
Status: ACTIVE_NOT_RECRUITING
Conditions: Overweight|Obesity
Interventions: DRUG: Tirzepatide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Novel Approaches for Improving Vascular Function in Veterans With HFpEF
Status: RECRUITING
Conditions: HFpEF - Heart Failure With Preserved Ejection Fraction|Inflammation
Interventions: DRUG: L-Citrulline|DRUG: Placebo for L-Citrulline|DRUG: BH4|DRUG: Placebo for BH4|DRUG: Atorvastatin|DRUG: Placebo for Atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Esophageal Hypersensitivity Study in Healthy Volunteers
Status: COMPLETED
Conditions: Pain|Esophageal Sensitivity
Interventions: DRUG: AZD1386|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Prospan® Hustenzäpfchen - Investigation on Efficacy and Tolerability in Children
Status: UNKNOWN
Conditions: Symptoms of Acute Bronchitis Accompanied by Coughing
Interventions: DRUG: Suppositories containing Ivy leaves dry extract|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Platelet Rich Plasma Injection Plus Fat Grafting as Compared to Fat Grafting Alone on Burn Scar by Using Vancouver Scar Scale
Status: COMPLETED
Conditions: Burn
Interventions: PROCEDURE: Platelet Rich Plasma plus fat grafting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Inspiratory Muscle Training With Powerbreath Device in Patients With ALS
Status: COMPLETED
Conditions: Amyotrophic Lateral Sclerosis
Interventions: OTHER: Inspiratory Muscle Training with Powerbreath IMT device.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: MetronomIc CApecitabine and DOcetaxel as Second-line Chemotherapy for Advanced Gastric Cancer
Status: UNKNOWN
Conditions: Gastric Adenocarcinoma|Gastroesophageal Junction Adenocarcinoma
Interventions: DRUG: capecitabine|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 14 vs 24 Weeks HCV Treatment to Genotype 2/3 Patients With Rapid Virological Response
Status: COMPLETED
Conditions: Hepatitis C Virus Infection
Interventions: DRUG: Pegylated Interferon alfa 2b and ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Nutrition Intervention for Arthritis -3 (WCCR-ARTH3)
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: OTHER: Plant-based diet|OTHER: Supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pazopanib Hydrochloride in Treating Patients With Metastatic Kidney Cancer Who Have No Evidence of Disease After Surgery
Status: ACTIVE_NOT_RECRUITING
Conditions: Clear Cell Renal Cell Carcinoma|Stage IV Renal Cell Cancer AJCC v7
Interventions: PROCEDURE: Computed Tomography|PROCEDURE: Magnetic Resonance Imaging|DRUG: Pazopanib Hydrochloride|OTHER: Placebo Administration|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Beef Protein Supplementation in Endurance Athletes
Status: COMPLETED
Conditions: Dietary Modification
Interventions: DIETARY_SUPPLEMENT: Dietary Supplement: Beef Protein|DIETARY_SUPPLEMENT: Dietary Supplement: whey Protein|DIETARY_SUPPLEMENT: Dietary Supplement: CHO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: "Comparing the Plaque Removal Ability of Two Different Toothbrushes Among School Going CP Children
Status: COMPLETED
Conditions: Cerebral Palsy
Interventions: OTHER: Comparing the plaque removal ability of triple head tooth brush versus single head tooth brush among school based cerebral palsy children: A Randomized Control Trial
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Impact of Different Skin Suture Methods in Episiotomy Repair on Healing and Pain
Status: COMPLETED
Conditions: Labor; Prolonged, Second Stage|Episiotomy Wound
Interventions: PROCEDURE: Matress Suturing|PROCEDURE: Primary Suturing|PROCEDURE: Continuous Subcutaneous Suturing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study Characterizing the Pharmacokinetic Profile of a Novel Encapsulated Caffeine Beverage in the Fed and Fasted States
Status: COMPLETED
Conditions: Pharmacokinetics
Interventions: OTHER: 250 mg encapsulated caffeine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of IDO Inhibitor and Temozolomide for Adult Patients With Primary Malignant Brain Tumors
Status: COMPLETED
Conditions: Glioblastoma Multiforme|Glioma|Gliosarcoma|Malignant Brain Tumor
Interventions: DRUG: Indoximod|DRUG: Temozolomide|DRUG: Bevacizumab|RADIATION: Stereotactic Radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preoperative Oral ImmunoNuTrition to Improve Surgical Outcomes for IBD Patients (PINT)
Status: WITHDRAWN
Conditions: Inflammatory Bowel Diseases
Interventions: DRUG: Nestle IMPACT Immunonutrition|OTHER: Arm B- Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of Secondary Infusion of Relmacabtagene Autoleucel Injection for Relapsed or Refractory B-cell Lymphoma
Status: NOT_YET_RECRUITING
Conditions: Relapsed or Refractory B-cell Lymphoma
Interventions: DRUG: Relmacabtagene Autoleucel Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combined Theta-gamma STN Stimulation for Verbal Fluency in Parkinson Disease
Status: RECRUITING
Conditions: Parkinson Disease
Interventions: OTHER: STN-DBS Theta Gamma Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: International, Multicenter Study of a Twenty-eight Week, Open-label, Titrated Oral Lixivaptan Administration in Patients With Chronic Hyponatremia: Extension to Studies CK-LX3401, 3405, and 3430
Status: COMPLETED
Conditions: Hyponatremia With Normal Extracellular Fluid Volume|Hyponatremia With Excess Extracellular Fluid Volume
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Single Dose Study of SHR4640 in Healthy Male Volunteers
Status: COMPLETED
Conditions: Gout
Interventions: DRUG: SHR4640|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: To Evaluate the Efficacy and Safety of Shampoo TD03 and TD07 in Scalp Diseases
Status: UNKNOWN
Conditions: Scalp Dermatitis
Interventions: OTHER: TD03|OTHER: TD07|DRUG: Ketoconazole 2% Shampoo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Omission of Sentinel Node Biopsy in Patients With Estrogen-Positive Breast Cancer Over Age 65
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer
Interventions: PROCEDURE: Lumpectomy without sentinel node biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Sorafenib as Adjuvant and Latter Radiofrequency Ablation for Recurrent Hepatocellular Carcinoma
Status: UNKNOWN
Conditions: HCC
Interventions: PROCEDURE: RFA|DRUG: Sorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of a Crowdsourced Cognitive Reappraisal Intervention
Status: COMPLETED
Conditions: Depression
Interventions: BEHAVIORAL: Crowdsourcing reappraisal intervention|BEHAVIORAL: Expressive writing intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Parathyroid Auto-transplantation: Prospective Randomized Trial of the Personalized Site
Status: UNKNOWN
Conditions: Parathyroid Autologous Transplantation
Interventions: PROCEDURE: injection with a syringe in new-site for parathyroid autografting|PROCEDURE: injection with a syringe in traditional site for parathyroid autografting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Mitochondrial Derived Reactive Oxygen Species on Cardiovascular Health in Chronic Obstructive Pulmonary Disease (COPD)
Status: RECRUITING
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: MitoQ|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Nebulized Hypertonic Saline in the Treatment of Acute Bronchiolitis
Status: COMPLETED
Conditions: Bronchiolitis
Interventions: DRUG: Hypertonic saline|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Interactive Exoskeleton Robot for Walking - Ankle Joint
Status: COMPLETED
Conditions: Stroke
Interventions: DEVICE: Ankle Robot with Power Assistance|DEVICE: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Mechanical Traction and Therapeutic Exercises in Treatment of Primary Knee Osteoarthritis
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: OTHER: Mechanical knee traction|OTHER: Therapeutic exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Airway Inflammatory Profile Among Cleaning Workers From Different Workplaces
Status: COMPLETED
Conditions: Inflammation|Work Related Illnesses|Symptoms and Signs|Asthma, Occupational|Rhinitis
Interventions: OTHER: Nasal swab|OTHER: Questionnaires
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: A 2-Part Study to Evaluate the Safety of Supra-Therapeutic Doses of RO4602522 and to Investigate the Effect of RO4602522 on the QTc Interval
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: OTHER: Placebo RO4602522|DRUG: RO4602522|DRUG: RO4602522|DRUG: moxifloxacin|OTHER: moxifloxacin placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Novel Antidiabetic Medications and Their Effect on Liver Steatosis (NAMELS-18)
Status: COMPLETED
Conditions: Non-Alcoholic Fatty Liver Disease|Liver Steatosis
Interventions: DRUG: Empagliflozin|DRUG: Dulaglutide|DRUG: Control Rx
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Tecemotide (L-BLP25) in Subjects With Slowly Progressive Multiple Myeloma With no Symptoms and Who Have Had no Chemotherapy
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: BIOLOGICAL: Tecemotide (L-BLP25)|BIOLOGICAL: Tecemotide (L-BLP25)|DRUG: Single low dose cyclophosphamide|DRUG: Multiple low dose cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Recurrence Score-guiding Chemotherapy in Non-pCR HR Positive HER2 Negative Breast Cancer After Neoadjuvant Therapy
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low-Dose Weekly vs High-Dose Cisplatin
Status: RECRUITING
Conditions: Locally Advanced Head and Neck Squamous Cell Carcinoma
Interventions: DRUG: High-Dose Cisplatin|DRUG: Low-Dose Cisplatin|RADIATION: Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Vitamin D Supplementation in Cutaneous Malignant Melanoma Outcome
Status: COMPLETED
Conditions: Cutaneous Malignant Melanoma
Interventions: DRUG: Vitamin D|DRUG: arachides oleum raffinatum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: In Vitro Effect Study of Interleukin-2 Muteins on Regulatory T Cells of Patients With Different Autoimmune, Allo-immune or Inflammatory Diseases
Status: UNKNOWN
Conditions: Autoimmune Diseases|Inflammatory Disease|Acquired Bone Marrow Aplasia|Systemic Lupus Erythematosus|Multiple Sclerosis|Gvhd|Rheumatoid Arthritis|Autoimmune Thyroiditis|Vitiligo|Alopecia|Atopic Dermatitis
Interventions: OTHER: Blood sample taken at a single time point
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Oxytocin on Masked Facial Expressions: an fMRI Study
Status: COMPLETED
Conditions: Facial Expressions
Interventions: DRUG: Oxytocin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Non-interventional Study of REVLIMID® (Lenalidomide) Treatment of IPSS Low- or Intermediate-1-risk Myelodysplastic Syndromes Associated With a Deletion 5q or Refractory/Relapsed Mantle Cell Lymphoma in Korea
Status: COMPLETED
Conditions: Myelodysplastic Syndromes|Lymphoma, Mantle-Cell|Lymphoma, Follicular
Interventions: DRUG: REVLIMID®
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy, Safety, and Tolerability of SR750 in Patients With Trigeminal Neuralgia
Status: NOT_YET_RECRUITING
Conditions: Trigeminal Neuralgia
Interventions: DRUG: SR750 tablet|DRUG: SR750 tablet|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Time-in-bed Restriction in Older Adults With Sleep Difficulties With and Without Risk for Alzheimer's Disease
Status: RECRUITING
Conditions: Alzheimer Disease, Late Onset|Mild Cognitive Impairment|Sleep|Cognitive Change|Amyloid
Interventions: BEHAVIORAL: Time in Bed Restriction|BEHAVIORAL: Sleep Schedule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Survival of Peritoneal Mesothelioma After Cytoreductive Surgery and Hyperthermic Intra-peritoneal Chemotherapy (HIPEC)
Status: COMPLETED
Conditions: Peritoneal Mesotheliomas
Interventions: PROCEDURE: Cytoreductive surgery and HIPEC
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Five-Tier, Open-Label Study of IMC-A12 in Advanced Sarcoma
Status: COMPLETED
Conditions: Ewing's Sarcoma /Peripheral Neuroectodermal Tumor (PNET)|Rhabdomyosarcoma|Leiomyosarcoma|Adipocytic Sarcoma|Synovial Sarcoma
Interventions: BIOLOGICAL: IMC-A12 (cixutumumab)|BIOLOGICAL: IMC-A12 (cixutumumab)|BIOLOGICAL: IMC-A12 (cixutumumab)|BIOLOGICAL: IMC-A12 (cixutumumab)|BIOLOGICAL: IMC-A12 (cixutumumab)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Propofol and Sevoflurane as a Primary Anesthetic for Cardiac Ablation of Atrial Fibrillation.
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DRUG: propofol|DRUG: sevoflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of an Investigational Nasal Aerosol or Placebo in Children (Ages 4 to 11) With Perennial Allergic Rhinitis (PAR)
Status: COMPLETED
Conditions: Allergic Rhinitis
Interventions: DRUG: BDP Nasal Aerosol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Leuven Interactive Scheme for hearingTraining Evaluation, and Audiological Rehabilitation
Status: ACTIVE_NOT_RECRUITING
Conditions: Hearing Disability
Interventions: BEHAVIORAL: Audiological rehabilitation|BEHAVIORAL: Placebo Rehabilitation|BEHAVIORAL: Passive Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: tDCS Plus Physical Therapy for Progressive Supranuclear Palsy
Status: COMPLETED
Conditions: Progressive Supranuclear Palsy|Parkinsonism|Parkinsonian Disorders
Interventions: DEVICE: transcranial direct current stimulation (tDCS)|BEHAVIORAL: Physical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Anticancer Therapeutic Vaccination Using Telomerase-derived Universal Cancer Peptides in Glioblastoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Glioblastoma
Interventions: DRUG: UCPVax|DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Paravertebral Muscle Fat Infiltration on Rocuronium Use in Lumbar Surgery
Status: COMPLETED
Conditions: Spinal Stenosis Lumbar
Interventions: DRUG: Rocuronium Bromide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: OTHER
Clinical trial: BedMed-Frail: Does the Potential Benefit of Bedtime Antihypertensive Prescribing Extend to Frail Populations?
Status: COMPLETED
Conditions: Hypertension|Dementia
Interventions: OTHER: Bedtime administration of the participant's pre-existing antihypertensive medications
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Outcome of 15 Versus 5 Fractions in Adjuvant Breast Radiotherapy in Women Over 65 Years
Status: ACTIVE_NOT_RECRUITING
Conditions: Breastcancer
Interventions: RADIATION: WBI 5 fractions|RADIATION: WBI 15 fractions|RADIATION: LNI 5 fractions|RADIATION: LNI 15 fractions|RADIATION: SIB 5 fractions if needed|RADIATION: SIB 15 fractions if needed|RADIATION: TWI 5 fractions|RADIATION: TWI 15 fractions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Metformin Hydrochloride vs. Placebo in Overweight or Obese Patients at Elevated Risk for Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer|Obesity
Interventions: DRUG: metformin hydrochloride|OTHER: placebo|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Study to Evaluate R2R01 Plus Terlipressin Versus Terlipressin Alone in Patients With Hepatorenal Syndrome
Status: RECRUITING
Conditions: Hepatorenal Syndrome|Acute Kidney Injury
Interventions: DRUG: R2R01|DRUG: Terlipressin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of Myofascial Release on Dysphagia in Stroke Survivors
Status: RECRUITING
Conditions: Dysphagia
Interventions: BEHAVIORAL: Rehabilitation treatment|BEHAVIORAL: Myofascial Release Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: TWB-103 for Adult Patients With Split-Thickness Skin Graft Donor Site Wounds
Status: COMPLETED
Conditions: Donor Site Complication
Interventions: DRUG: TWB-103 Group|DRUG: Placebo Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Retrospective rEal-life daTa Study to Assess the exaceRbations and Lung functIon in Chronic Obstructive Pulmonary Disease ( COPD ) patiEnts receiVing Fluticasone/Salmeterol Comparing to Those Εscalating in Open-triple Fluticasone/Salmeterol, Long Acting Muscarinic Antagonist (LAMA) Combination
Status: COMPLETED
Conditions: COPD|COPD Exacerbation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Multicenter Phase 1b Trial Testing the Neoadjuvant Combination of Domatinostat, Nivolumab and Ipilimumab in IFN-gamma Signature-low and IFN-gamma Signature-high RECIST 1.1-measurable Stage III Cutaneous or Unknown Primary Melanoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Malignant Melanoma Stage III
Interventions: DRUG: Domatinostat|DRUG: Nivolumab|DRUG: Ipilimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Compare the Efficacy and Patient's Satisfaction From Pain Management of Women After Cesarean Section by Pain Relievers' Administration in Fix Protocol Compared to Protocol Following Demand
Status: COMPLETED
Conditions: Pain Management|Cesarean Section
Interventions: DRUG: Fix protocol|DRUG: medications following demand protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Controlled Trial of Combined Letrozole and Clomid (CLC II) Versus Letrozole Alone for Women With Anovulation
Status: ACTIVE_NOT_RECRUITING
Conditions: Polycystic Ovary Syndrome|PCOS|Infertility
Interventions: DRUG: Letrozole|DRUG: Clomiphene Citrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Protocol of Diuretics Use in Congestive Therapy in Heart Failure
Status: UNKNOWN
Conditions: Heart Failure|Acute Heart Failure|Chronic Heart Failure
Interventions: DRUG: Furosemide|DRUG: Hydrochlorothiazide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Non-invasive Measurement of Retinal Blood Flow Based on Vessel Analysis and Fourier Domain Optical Coherence Tomography in Patients With Hypertensive Retinopathy
Status: UNKNOWN
Conditions: Hypertensive Retinopathy
Interventions: DEVICE: Dynamic Vessel Analyzer|OTHER: FDOCT|OTHER: Ocular perfusion pressure
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Early Resuturing Versus Expectant Management Following Perineal Wound Dehiscence Among Women Who Had a Vaginal Delivery
Status: UNKNOWN
Conditions: Wound; Perineal Rupture, Dehiscence
Interventions: PROCEDURE: Resuturing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized, Double-blind, Placebo Controlled Comparison of Telmisartan Hydrochlorothiazide (HCT) and Valsartan HCT in Hypertension (HTN) Stage I/II Patients
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: telmisartan 80 mg/hydrochlorothiazide 25 mg|DRUG: valsartan 160 mg/hydrochlorothiazide 25 mg|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of a Herbal Supplement in the Prevention of PTSD
Status: COMPLETED
Conditions: PTSD, Post Traumatic Stress Disorder|Diagnosis, Psychiatric|Follow up
Interventions: DRUG: aleozen|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Covid-19 Convalescent Plasma as Prevention and Treatment for Children With Underlying Medical Conditions
Status: NOT_YET_RECRUITING
Conditions: Corona Virus Infection
Interventions: BIOLOGICAL: anti-SARS-CoV-2 human convalescent plasma
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 1, Dose Escalation Study Evaluating the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of SM04690 in Moderate to Severe Knee Osteoarthritis (OA)
Status: COMPLETED
Conditions: Moderate to Severe Osteoarthritis
Interventions: DRUG: SM04690, 0.03mg/2mL|DRUG: SM04690, 0.07mg/2mL|DRUG: SM04690, 0.23mg/2mL|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Neuroprosthesis for Seated Posture and Balance
Status: RECRUITING
Conditions: Spinal Cord Injury|Paralysis|Tetraplegia|Paraplegia
Interventions: DEVICE: IRS-8 (8-Channel implanted stimulator-telemeter)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ATAGLU: Study of Glucose Metabolism in HIV Positive Patients That Switch From Another Protease Inhibitor to Atazanavir
Status: UNKNOWN
Conditions: HIV
Interventions: DRUG: Atazanavir
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ceritinib + Trametinib in Patients With Advanced ALK-Positive Non-Small Cell Lung Cancer (NSCLC)
Status: TERMINATED
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: Ceritinib|DRUG: Trametinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Prazosin in Bulimic Patients Experiencing Nightmares Due to PTSD
Status: COMPLETED
Conditions: Stress Disorders, Post-Traumatic|Bulimia Nervosa
Interventions: DRUG: Prazosin|DRUG: Placebo|DRUG: Prazosin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study in Schizophrenia Patients
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Risperidone|DRUG: Placebo|DRUG: LY2140023
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Inhaled Sevofluran vs Endovenous Propofol for Colonoscopy
Status: COMPLETED
Conditions: Anesthesia
Interventions: DRUG: Propofol|DRUG: Sevoflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy and Safety of Deep Brain Stimulation in Mesencephalic Locomotor Region（MLR） for Poststroke Hemiplegia
Status: NOT_YET_RECRUITING
Conditions: Stroke Sequelae
Interventions: PROCEDURE: MLR-DBS|PROCEDURE: Conventional rehabilitation group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Real-time Continuous Glucose Monitoring System in Patients With Type 1 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: DEVICE: Guardian REAL-Time Continuous Glucose Monitoring System|OTHER: Conventional self-monitoring of plasma glucose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of the Safety and Efficacy of 3VM1001 Cream for Treatment of Chronic Pain Caused by Knee Osteoarthritis.
Status: UNKNOWN
Conditions: Osteoarthritis of Knee
Interventions: DRUG: 3VM1001|DRUG: Placebo for 3VM1001
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Anti-Hep B Antibodies at Age 12 to 18 Months After Hep B Vaccine at Birth and DTaP-IPV-Hep B-PRP-T Hexavalent Vaccine Concomitantly With Prevnar® at 2, 4 and 6 Months of Age
Status: COMPLETED
Conditions: Hepatitis B
Interventions: BIOLOGICAL: DTaP-IPV-HB-PRP~T and Pneumococcal polysaccharide vaccines|BIOLOGICAL: DTaP-HB-IPV and Pneumococcal polysaccharide vaccines
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Home Rehabilitation Using Interactive Device Versus Inpatient Rehabilitation in Total Knee Arthroplasty
Status: UNKNOWN
Conditions: Osteoarthritis, Knee|Arthroplasty|Rehabilitation
Interventions: DEVICE: Home Rehabilitation using Interactive device|OTHER: Inpatient Rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cyclophosphamide, Methotrexate, and Prednisolone With or Without Aromatase Inhibitor Therapy in Treating Postmenopausal Women With Metastatic Breast Cancer
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: DRUG: anastrozole|DRUG: cyclophosphamide|DRUG: exemestane|DRUG: letrozole|DRUG: methotrexate|DRUG: prednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Folic Acid Supplementation on Arsenic Lowering
Status: UNKNOWN
Conditions: Arsenic Poisoning|Toxic Effect of Arsenic and Its Compounds
Interventions: DRUG: folic acid supplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Treatment of Psychosis and Agitation in Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer's Disease|Psychosis|Agitation
Interventions: DRUG: Lithium|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Umbilical Cord Derived Mesenchymal Stem Cells Therapy in Ischemic Cardiomyopathy
Status: UNKNOWN
Conditions: Ischemic Cardiomyopathy
Interventions: BIOLOGICAL: mesenchymal stem cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: S0636: Erlotinib and Bevacizumab in Never-Smokers With Stage IIIB or Stage IV Primary Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer
Interventions: BIOLOGICAL: bevacizumab|DRUG: erlotinib hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Antenatal Exercises on Clinical Outcomes in Pregnant Females With Gestational Diabetes Mellitus
Status: COMPLETED
Conditions: Gestational Diabetes
Interventions: OTHER: routine physical therapy|OTHER: routine physical therapy and antenatal exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trials of Prosthesis and Surgery Guide System
Status: UNKNOWN
Conditions: Knee Osteoarthritis
Interventions: DEVICE: Personalized TKA prosthesis|DEVICE: Zimmer NexGen prostheses
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Efficacy of Rucaparib in Metastatic Breast Cancer Patients With a BRCAness Genomic Signature
Status: COMPLETED
Conditions: Metastatic Breast Cancer
Interventions: DRUG: rucaparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial of Three Types of Enemas Used to Treat Functional Constipation in Children
Status: TERMINATED
Conditions: Functional Constipation
Interventions: DRUG: Sodium phosphate enema|DRUG: Normal saline enema|DRUG: Mineral oil enema
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT