pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Randomized Study Comparing Ranibizumab to Sham in Patients With Macular Edema Secondary to CRVO
Status: COMPLETED
Conditions: Central Retinal Vein Occlusion|Macular Edema
Interventions: DRUG: ranibizumab|DRUG: ranibizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pembrolizumab and Brentuximab Vedotin vs GDP and Stem Cell Transplant for Relapsed/Refractory Hodgkin Lymphoma
Status: RECRUITING
Conditions: Hodgkin Lymphoma
Interventions: DRUG: Gemcitabine|DRUG: Dexamethasone|DRUG: Cisplatin|DRUG: Brentuximab vedotin|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Hippophae Rhamnoides L. Leaf Extract on Body Fat
Status: COMPLETED
Conditions: Obesity
Interventions: DIETARY_SUPPLEMENT: Hippophae rhamnoides L. Leaf Extract (3g/day)|DIETARY_SUPPLEMENT: Placebo (3g/day)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Neoadjuvant Tucidinostat and Exemestane in Early Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Tucidinostat|DRUG: Exemestane|DRUG: Ovarian function suppression
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Riluzole as a Symptomatic Approach in Patients With Chronic Cerebellar Ataxia
Status: COMPLETED
Conditions: Hereditary Ataxia|Multiple Sclerosis|Cerebellar Ataxia
Interventions: DRUG: Riluzole|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II Study of Tocilizumab for Patients With Glucocorticoid-refractory Acute GVHD After Allogeneic Hematopoetic Stem Cell Transplant (HSCT)
Status: TERMINATED
Conditions: Glucocorticosteroid Refractory Acute GVHD
Interventions: DRUG: Toclizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of RoActemra/Actemra (Tocilizumab) in Combination With Methotrexate Versus RoActemra/Actemra Monotherapy in Patients With Rheumatoid Arthritis and an Inadequate Response to Methotrexate
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: methotrexate|DRUG: methotrexate|DRUG: placebo|DRUG: tocilizumab [RoActemra/Actemra]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety, Tolerability, and Immunogenicity of a Modified RNA Vaccine Against Influenza
Status: COMPLETED
Conditions: Influenza, Human
Interventions: BIOLOGICAL: mIRV|BIOLOGICAL: bIRV AB|BIOLOGICAL: qIRV|BIOLOGICAL: QIV|BIOLOGICAL: bIRV AA|BIOLOGICAL: bIRV BB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparisons of Inhaled LAMA or LAMA+LABA or ICS+LABA for COPD With Bronchiectasis
Status: UNKNOWN
Conditions: COPD|Bronchiectasis
Interventions: DRUG: Symbicort|DRUG: Spiriva
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pulse Wave Velocity, Tacrolimus Time in Therapeutic Range and CV in African American Kidney Transplants
Status: RECRUITING
Conditions: Kidney Transplant; Complications
Interventions: DRUG: Extended Release Tacrolimus Tablets|DRUG: Immediate Release Tacrolimus Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Compare 3 Multi-Layered Foam Dressings for the Management of Chronic Wounds
Status: COMPLETED
Conditions: Chronic Wound|Venous Leg Ulcer|Diabetic Foot Ulcer
Interventions: DEVICE: Bordered Five-Layer Foam Dressing|DEVICE: Hydropolymer Foam Dressing|DEVICE: Hydrocellular Multi-Layer Foam Dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Use of Manual Therapy to Treat Low-Back and Hip Pain
Status: COMPLETED
Conditions: Low Back Pain|Pain
Interventions: PROCEDURE: Osteopathic Manipulative Medicine|PROCEDURE: Sham Manipulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Contribution of High Throughput RNA Sequencing Combined With Sequencing of Whole Genomes in the Diagnosis of Intellectual Disability
Status: COMPLETED
Conditions: Patients With Intellectual Disabilities Without an Obvious Clinical Diagnosis|Patients With Normal Array CGH and Previous Negative Genetic Investigations (WES-solo or WES-trio)
Interventions: BIOLOGICAL: Patient blood sampling|BIOLOGICAL: Parents blood sampling
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: GM-CSF as Adjuvant Therapy of Melanoma
Status: COMPLETED
Conditions: Malignant Melanoma
Interventions: DRUG: Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Benefits of a Novel Sleep-focused Mind-body Program on Gulf War Illness (GWI) Symptoms
Status: COMPLETED
Conditions: Sleep Disturbance|Persian Gulf War Syndrome in Veteran
Interventions: BEHAVIORAL: Mind-Body Bridging Program|BEHAVIORAL: Supportive Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Identify Subjects at Risk for Falling Using Acceleration Based Gait Analysis System
Status: UNKNOWN
Conditions: Fall Risk
Interventions: DEVICE: fall related movement (stumble) detector|DEVICE: fall related movement characteristic (stumble) detector
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Phase III Clinical Trial of PROCRIT (Epoetin Alfa) Versus Placebo in Women Undergoing Adjuvant Chemotherapy for Stage I, II or III Breast Cancer
Status: TERMINATED
Conditions: Anemia|Breast Neoplasms|Hemoglobins|Quality of Life|Chemotherapy, Adjuvant
Interventions: DRUG: epoetin alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Topical Phenylephrine Gel in the Management of Faecal Incontinence
Status: WITHDRAWN
Conditions: Faecal Incontinence
Interventions: DRUG: 10% Phenylephrine hydrochloride gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Implementation of a System-level Tobacco Treatment Intervention
Status: ACTIVE_NOT_RECRUITING
Conditions: Smoking Cessation|Lung Cancer
Interventions: OTHER: CEASE|OTHER: Usual Care Tobacco Treatment Services
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Clinical Study of UMOD NKCC2 Interaction on Salt-sensitivity in Hypertension
Status: COMPLETED
Conditions: Cardiovascular Diseases|Hypertension
Interventions: DRUG: Torasemide 5Mg Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Enteral Versus Parenteral Glutamine Supplement
Status: TERMINATED
Conditions: Critically Ill
Interventions: DIETARY_SUPPLEMENT: parenteral glutamine|DIETARY_SUPPLEMENT: enteral glutamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nutritional Intervention With Table Olives in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy|Biological Availability|Nutritional Intervention|Functional Food|Nutrition Physiology
Interventions: OTHER: Table Olives|OTHER: Table Olives|OTHER: Table Olives
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Trial of Diabetes-educated Psychologist to Improve HbA1c and Reduce Diabetes-related Distress
Status: ACTIVE_NOT_RECRUITING
Conditions: Type1diabetes|Psychology Functional Behavior
Interventions: BEHAVIORAL: Treatment by a diabetes educated psychologist
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of Two Meningococcal ACWY Conjugate Vaccines
Status: COMPLETED
Conditions: Meningococcal Meningitis
Interventions: BIOLOGICAL: Menveo|BIOLOGICAL: MenACWY-TT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study to Evaluate the Efficacy and Safety of Camidanlumab Tesirine (ADCT-301) in Patients With Relapsed or Refractory Hodgkin Lymphoma
Status: COMPLETED
Conditions: Relapsed Hodgkin Lymphoma|Refractory Hodgkin Lymphoma
Interventions: DRUG: Camidanlumab Tesirine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nebulized RNS60 for the Treatment of Amyotrophic Lateral Sclerosis
Status: NOT_YET_RECRUITING
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DRUG: RNS60|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Local Ketamine Instillation for Postoperative Analgesia
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: intra-wound instillation of ketamine|DRUG: intra-wound instillation of normal saline|DRUG: systemic administration of ketamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Exogenous Testosterone Plus Dutasteride for the Treatment of Castrate Metastatic Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer|Castration-resistant, Metastatic
Interventions: OTHER: testosterone (AndroGel®) with the 5α-reductase inhibitor dutasteride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical and Immunological Features of the CMV Infection Atypical Course in Immunocompetent Individuals
Status: ENROLLING_BY_INVITATION
Conditions: CMV
Interventions: DIAGNOSTIC_TEST: Bood leukocyte subsets|DIAGNOSTIC_TEST: CMV specific T-cells|DIAGNOSTIC_TEST: serum CMV IgM / IgG antibodies
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Hyperoxia on Open Heart Surgery
Status: UNKNOWN
Conditions: Heart Valve Disease|Coronary (Artery) Disease
Interventions: OTHER: Fraction of inspired oxygen 40%|OTHER: Fraction of inspired oxygen 100%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Arthroscopic Rotator Interval Closure in Shoulder Instability Repair
Status: UNKNOWN
Conditions: Recurrent Shoulder Dislocations
Interventions: PROCEDURE: Arthroscopic Bankart repair|PROCEDURE: ABR+ARIC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Feasibility Study to Evaluate The Effect of the Electronic Patient Visit Assessment On Pain and Quality of Life for Patients With Head and Neck Cancer (HNC)
Status: UNKNOWN
Conditions: Head and Neck Cancer
Interventions: BEHAVIORAL: Electronic Patient Visit Assessment (ePVA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Verapamil in Supraclavicular Brachial Plexus Block
Status: UNKNOWN
Conditions: Regional Anesthesia Morbidity
Interventions: DIAGNOSTIC_TEST: complete blood count|DIAGNOSTIC_TEST: prothrombin time|DIAGNOSTIC_TEST: prothrombin concentration|DRUG: Verapamil
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: A Study of Mircera for the Treatment of Anemia in Dialysis Patients
Status: COMPLETED
Conditions: Anemia
Interventions: DRUG: epoetin|DRUG: methoxy polyethylene glycol-epoetin beta [Mircera]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Local Host Modulating Agents Alendronate & Aloe Vera for Treatment of Furcation Defects in Chronic Periodontitis
Status: COMPLETED
Conditions: Chronic Periodontitis
Interventions: DRUG: placebo|DRUG: Alendronate|DRUG: Aloe Vera
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Open-label Trial on the Effect of I.V. Zoledronic Acid 4 mg on Bone Density in Hormone Sensitive Prostate Cancer Patients With Bone Metastasis
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: Zometa
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pre-Operative Pembrolizumab + Chemoradiation in Patients With Locally Advanced Esophageal Squamous Cell Carcinoma
Status: COMPLETED
Conditions: Esophageal Squamous Cell Carcinoma
Interventions: DRUG: Pembrolizumab Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Continuous Positive Airway Pressure (CPAP) Treatment in Coronary Artery Disease and Sleep Apnea
Status: COMPLETED
Conditions: Coronary Artery Disease|Obstructive Sleep Apnea
Interventions: DEVICE: ResMed S8 (Auto-CPAP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Carvedilol and Atenolol on Anti-anginal and Metabolic Effects in Patients With Stable Angina Pectoris
Status: COMPLETED
Conditions: Stable Angina Pectoris
Interventions: DRUG: Carvedilol|DRUG: Atenolol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Study to Evaluate Safety & Efficacy of RM-131 Administered to Patients With Diabetic Gastroparesis
Status: COMPLETED
Conditions: Diabetes Mellitus|Diabetes Mellitus Complications|Gastroparesis
Interventions: DRUG: RM-131|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Implementing, Evaluating, and Scaling Up of the Strengthening a Palliative Approach in Long Term Care (SPA-LTC) Program
Status: ACTIVE_NOT_RECRUITING
Conditions: Frail Elderly Syndrome
Interventions: OTHER: Strengthening a Palliative Approach in Long-Term Care (SPA-LTC) Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A 16 Week Study of HRS-7535 in Adults With Type 2 Diabetes Mellitus
Status: NOT_YET_RECRUITING
Conditions: Type 2 Diabetes
Interventions: DRUG: HRS-7535|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Bioavailability Study of Levetiracetam Tablets, 750 mg of Dr. Reddy's Under Fasting Conditions.
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Levetiracetam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Should Non-eosinophilic Asthmatic Subjects be Treated With Inhaled Corticosteroids?
Status: TERMINATED
Conditions: Asthma
Interventions: DRUG: Placebo (sham inhaler)|DRUG: Fluticasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Customized Adherence Enhancement Plus Long-acting Injectable Antipsychotic
Status: COMPLETED
Conditions: Patient Noncompliance
Interventions: DRUG: haloperidol decanoate|DRUG: haloperidol|BEHAVIORAL: Customized Adherence Enhancement
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Change of Lung Function After Exercise in Patients With Chronic Obstructive Pulmonary Disease
Status: UNKNOWN
Conditions: Pulmonary Disease, Chronic Obstructive|Exercise|Lung Function Decreased|Quality of Life
Interventions: DRUG: Budesonide and formoterol bid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Non-surgical Periodontal Therapy in the Improvement of Early Endothelial Dysfunction in Subjects With Periodontitis.
Status: COMPLETED
Conditions: Atherosclerosis|Periodontitis
Interventions: PROCEDURE: Non-surgical periodontal treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Protocol to Investigate the Efficacy of Recombinant Human Leptin (Metreleptin) in Nonalcoholic Steatohepatitis (NASH) or Nonalcoholic Fatty Liver Disease (NAFLD) Associated With Lipodystrophy
Status: COMPLETED
Conditions: Fatty Liver Disease, Nonalcoholic|Nonalcoholic Steatohepatitis|Lipodystrophy
Interventions: DRUG: Metreleptin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Safety and Performance of LiNiDERM® in the Prevention of Infant Diaper Rash
Status: COMPLETED
Conditions: Diaper Rash
Interventions: DEVICE: Liniderm|OTHER: Wipes|OTHER: Water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Combined Use of Pulsed Dye Laser and Topical Antiangiogenic Agents for Treatment of Port Wine Stain Birthmarks
Status: WITHDRAWN
Conditions: Port Wine Stain
Interventions: DRUG: Topical Antiangiogenic|DEVICE: Pulsed Dye Laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Associated With Treating Erectile Dysfunction Patients With Low Intensity Shockwaves by Renova
Status: TERMINATED
Conditions: Vasculogenic Erectile Dysfunction
Interventions: DEVICE: Low Intensity Shockwave by Renova|DEVICE: Sham treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An Extension Study to Provide Bortezomib to Patients With Relapsed or Refractory Multiple Myeloma Who Previously Participated in a Bortezomib Phase I/II Study and Who May Benefit From Re-Treatment With or Continuation of Bortezomib Therapy
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: bortezomib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Effectiveness of a Computer Decision Support System to Improve Physicians' Screening for Autism
Status: COMPLETED
Conditions: Healthy Children Undergoing Routine Care|Children With Autism
Interventions: OTHER: Computer based care reminders
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: OCT and Invasion in Cutaneous Skin Lesions
Status: ACTIVE_NOT_RECRUITING
Conditions: Cutaneous Squamous Cell Carcinoma|Bowen's Disease|Actinic Keratoses|Keratosis, Actinic|Diagnosis
Interventions: DIAGNOSTIC_TEST: Optical Coherence Tomography|OTHER: Clinical assessment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Brain Image Markers Associated With Cognitive Training and Aerobic Exercise in Schizophrenia
Status: UNKNOWN
Conditions: Schizophrenia
Interventions: BEHAVIORAL: Aerobic Exercise|BEHAVIORAL: Cognitive Training|BEHAVIORAL: Treatment as usual|BEHAVIORAL: Occupational Activities
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Regulation of Intraocular Pressure in Glaucoma Patients by Acupressure
Status: COMPLETED
Conditions: Primary Open Angle Glaucoma|Acupressure
Interventions: BEHAVIORAL: Acupressure
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Effect of Delafloxacin on the Pharmacokinetics of Midazolam in Healthy Subjects
Status: COMPLETED
Conditions: VA Drug Interactions
Interventions: DRUG: Midazolam|DRUG: Delafloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Combination Chemotherapy and Bevacizumab as First-Line Therapy in Treating Patients With Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: BIOLOGICAL: bevacizumab|DRUG: fluorouracil|DRUG: irinotecan hydrochloride|DRUG: leucovorin calcium|DRUG: oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating the Safety, Tolerability, and Pharmacokinetics of Single Doses and Multiple Doses of BIIB059 (Litifilimab) in Healthy Volunteers and Participants With Systemic Lupus Erythematosus
Status: COMPLETED
Conditions: Systemic Lupus Erythematosus|Healthy Volunteers
Interventions: DRUG: BIIB059 (litifilimab)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study on the Immune Response and Safety of a Vaccine Against Respiratory Syncytial Virus (RSV) When Given Alone or Co-administered With an Adjuvanted Vaccine Against Influenza in Adults Aged 65 Years and Above
Status: COMPLETED
Conditions: Respiratory Syncytial Virus Infections
Interventions: BIOLOGICAL: RSVPreF3 OA vaccine|BIOLOGICAL: FLU vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Human BCMA Targeted T Cells Injection（BCMA CAR-T）for Subjects With R/R MM
Status: RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: Human BCMA Targeted T Cells Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Short Term Efficacy of a Starting Dose of 12.5 mg of Prednisone in Polymyalgia Rheumatica Patients
Status: COMPLETED
Conditions: Polymyalgia Rheumatica
Interventions: DRUG: prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Scrub Typhus Antibiotic Resistance Trial
Status: RECRUITING
Conditions: Scrub Typhus
Interventions: DRUG: Doxycycline 7 days|DRUG: Doxycycline 3 days|DRUG: Azithromycin 3 days
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Physiotherapy and Osteopathy on Infant Colic
Status: COMPLETED
Conditions: Infantile Colic|Manual Therapy
Interventions: OTHER: Osteopathy manual therapy|BEHAVIORAL: Measures to support and education to the family
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acute Retinal Detachment Repair With the iSeelr™ Retinal Detachment Repair System
Status: NOT_YET_RECRUITING
Conditions: Rhegmatogenous Retinal Detachment - Macula Off
Interventions: DEVICE: iSeelr™
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Predicting Adjuvant Post-operative Radiation Therapy in Patients With Cervical Cancer Stage IB2
Status: UNKNOWN
Conditions: Cancer of the Cervix|Conization of the Cervix|Radiation Therapy
Interventions: PROCEDURE: cervix biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effect of Subdural Drain Placement After Burr Hole Evacuation of Chronic Subdural Haematomas on Recurrence: a Prospective Randomised-controlled Multi-centre Study
Status: UNKNOWN
Conditions: Chronic Subdural Hematoma|Subdural Drain
Interventions: DEVICE: Silicon subdural drain placement after burr hole evacuation of chronic subdural hematoma
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Robot-assisted Walking Training on Hemiplegic Individuals
Status: COMPLETED
Conditions: Hemiplegia|Gait, Hemiplegic|Motor Function|Balance; Distorted
Interventions: BEHAVIORAL: Exercise Therapy|BEHAVIORAL: Exercise Therapy and Robotic Walking Training
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Grape Juice With Breakfast on Glycemia and Cognitive Function in Healthy Adults
Status: COMPLETED
Conditions: Glycemic Response|Appetitive Behavior
Interventions: OTHER: Concord Grape Juice|OTHER: Low flavonoid low essence beverage|OTHER: Low flavonoid beverage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Single Dose Crossover Study In Healthy Subjects To Evaluate Different Formulations Of PF-06882961
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: PF-06882961 Immediate Release Tablet|DRUG: PF-06882961 Controlled Release Tablet (long)|DRUG: PF-06882961 Controlled Release Tablet (short)|DRUG: PF-06882961 Immediate Release Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Sorafenib as Neoadjuvant Therapy Before Cytoreductive Nephrectomy in Patients With Metastatic Renal Cell Carcinoma
Status: COMPLETED
Conditions: Carcinoma, Renal Cell
Interventions: DRUG: Sorafenib (Nexavar, BAY 43-9006)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Zincoxide-propolis vs Zincoxide-eugenol Pulpectomy
Status: UNKNOWN
Conditions: Pulp Necroses
Interventions: DRUG: Zinc oxide Propolis|DRUG: Zinc Oxide-Eugenol Cement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Danavorexton in Anesthetized Adults
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Danavorexton|DRUG: Danavorexton Placebo|DRUG: Propofol|DRUG: Sevoflurane|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Clinical Pregnancy Rate After Removal of Unsuspected Polyps
Status: WITHDRAWN
Conditions: Infertility
Interventions: PROCEDURE: polypectomy|PROCEDURE: saline sonography|DRUG: normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: An Open Single Centre Study To Assess Treatment of Chronic Constipation in Children
Status: COMPLETED
Conditions: Chronic Constipation
Interventions: DRUG: Polyethylene glycol 3350 Na bicarbonate NaCl KCl
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Standardized Instruments to Provide Diagnostic and Prognostic Information in Mild Traumatic Brain Injury (mTBI)
Status: RECRUITING
Conditions: Mild Traumatic Brain Injury
Interventions: DEVICE: Diagnostic test
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Observational Study to Evaluate the Time to Achieving the Maintenance Dose of Zemplar® (Paricalcitol Injection) in the Treatment of Patients Suffering From End-stage Renal Disease and Severe Over-reactivity of the Parathyroid Glands
Status: COMPLETED
Conditions: Kidney Failure, Chronic
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: VSL#3 and Spontaneous Bacterial Peritonitis
Status: TERMINATED
Conditions: Decompensated Cirrhosis|Ascites
Interventions: DRUG: cotrimoxazole|DRUG: VSL#3 active|DRUG: VSL#3 placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Colony-Stimulating Factors in Treating Children With Recurrent or Refractory Solid Tumors
Status: COMPLETED
Conditions: Cancer
Interventions: BIOLOGICAL: recombinant human thrombopoietin|DRUG: carboplatin|DRUG: etoposide|DRUG: ifosfamide|BIOLOGICAL: G-CSF
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study To Investigate The Effect Of Inhaling A Single Dose Of GW642444M In Asthmatic Patients
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: GW642444H (100mcg)|DRUG: placebo|DRUG: GW642444M (25, 100 & 400 mcg)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Zanzibar Arts for Children's Eyesight Pilot Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Myopia|Conjunctivitis|Hyperopia
Interventions: BEHAVIORAL: School music broadcast|BEHAVIORAL: Community music broadcast
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of NMES Therapy for Pain Relief Associated With Knee Osteoarthritis
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: DEVICE: Home-based Neuromuscular Electrical Stimulation (NMES) therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study on the Prevalence of the Modified Citrullinated Vimentin Anti-body (Anti-MCV) in an Irish Rheumatoid Arthritis (RA) Population and to Assess the Impact of Anti-MCV and the Anti-cyclic-citrullinated Peptide Antibody (Anti-CCP) Status on the Management of Irish Patients With Early RA
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Prospective Study of 3 Phone Assistance Strategies to Achieve a Continuous Cardiac Massage
Status: COMPLETED
Conditions: Cardiac Arrest
Interventions: OTHER: Therapeutic and preventive strategies|OTHER: Therapeutic and preventive strategies|OTHER: Therapeutic and preventive strategies
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Ypeginterferon Alfa-2b in Chronic Hepatitis C
Status: COMPLETED
Conditions: Chronic Hepatitis C
Interventions: DRUG: Ypeginterferon alfa-2b|DRUG: Peginterferon alfa-2a
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Paclitaxel Protein Bound + Gemcitabine + Cisplatin + Hydrochloroquine as Treatment in Untreated Pancreas Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Untreated Resectable Pancreatic Adenocarcinoma|Borderline Resectable Pancreatic Adenocarcinoma|Locally Advanced Pancreatic Adenocarcinoma
Interventions: DRUG: Paclitaxel protein bound|DRUG: Gemcitabine|DRUG: Cisplatin|DRUG: Hydroxychloroquine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Role of iTBS in Bipolar II Depression
Status: RECRUITING
Conditions: Bipolar II Disorder, Most Recent Episode Major Depressive
Interventions: DEVICE: repetitive transcranial magnetic stimulation (rTMS)|DEVICE: sham repetitive transcranial magnetic stimulation (rTMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: De-intensification of Radiation & Chemotherapy in Low-Risk Human Papillomavirus-related Oropharyngeal Squamous Cell Ca
Status: COMPLETED
Conditions: Carcinoma, Squamous Cell|Head and Neck Neoplasms|Oropharyngeal Neoplasms
Interventions: RADIATION: Intensity Modulated Radiotherapy (IMRT)|DRUG: Cisplatin|PROCEDURE: Limited surgical evaluation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Validation and Dosimetry Study of GSK2634673F PET Ligand
Status: TERMINATED
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: OTHER: GSK2634673F
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: TMS for Improving Response Inhibition in Adolescents With OCD
Status: COMPLETED
Conditions: Obsessive-Compulsive Disorder
Interventions: DEVICE: Transcranial Magnetic Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ESWL Versus SOPIL for Treatment of Pancreatic Duct Stones
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Pancreatitis|Pancreatic Duct Stone
Interventions: PROCEDURE: ESWL vs SOPIL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Continuous Positive Airway Pressure (CPAP) Mode Impact on Clinical Blood Arterial Pressure
Status: COMPLETED
Conditions: Obstructive Sleep Apnea Syndrome
Interventions: DEVICE: S8 Spirit 2|DEVICE: Somnosmart 2|DEVICE: Remstar Auto
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Bevacizumab and Irinotecan in Treating Young Patients With Recurrent, Progressive, or Refractory Glioma, Medulloblastoma, Ependymoma, or Low Grade Glioma
Status: COMPLETED
Conditions: Childhood Cerebral Anaplastic Astrocytoma|Childhood Oligodendroglioma|Childhood Spinal Cord Neoplasm|Recurrent Childhood Brain Stem Glioma|Recurrent Childhood Ependymoma|Recurrent Childhood Medulloblastoma
Interventions: BIOLOGICAL: Bevacizumab|RADIATION: Fludeoxyglucose F-18|DRUG: Irinotecan Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HIRREM for Stage 1 Primary Hypertension
Status: COMPLETED
Conditions: Hypertension|Blood Pressure|Cardiovascular Diseases|Cardiovascular Risk Factor|Autonomic Nervous System Imbalance
Interventions: DEVICE: HIRREM|OTHER: Continued Current Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Protein Ingestion and Muscle Carnitine Uptake
Status: COMPLETED
Conditions: Muscle, Skeletal
Interventions: DIETARY_SUPPLEMENT: Flavoured water|DIETARY_SUPPLEMENT: Flavoured water + carbohydrate|DIETARY_SUPPLEMENT: Flavoured water + carbohydrate + protein
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Exploratory Study of MSLN-CAR T Cells Secreting PD1/CTLA-4 Nanoantibody for the Treatment of Advanced Solid Tumors
Status: RECRUITING
Conditions: Solid Tumor
Interventions: BIOLOGICAL: αPD1/CTLA4-MSLN-CAR T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Postoperative Analgesic Effect of Intrathecal Magnesium and Fentanyl Added to Bupivacaine in Patients Undergoing Lower Limb Orthopedic Surgery
Status: COMPLETED
Conditions: Post Operative Pain
Interventions: DRUG: Fentanyl|DRUG: placebo(distilled water)|DRUG: magnesium sulphate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Metabolic Effects of a Caloric Restriction High/Low Glycemic Index Diet Plus Metformin in Overweight/Obese Subjects
Status: COMPLETED
Conditions: Obesity
Interventions: OTHER: Glycemic Index Diets and Metformin hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MTC Versus FMT in for RCDI
Status: RECRUITING
Conditions: Clostridiodies Difficile Infections
Interventions: DRUG: MTC 01|DRUG: Fecal Microbiota Transplantation (FMT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effect of Local Anaesthetic Volume on Nerve Block Duration and Nerve Block Duration Variability
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: Ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Assess the Safety, Tolerability and Pharmacokinetics of Cardiotrophin-1 in Healthy Volunteers
Status: UNKNOWN
Conditions: Healthy
Interventions: DRUG: recombinant human cardiotrophin-1|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Collagen Implant (Biological Mesh) Versus GM Flap for Reconstruction of Pelvic Floor After ELAPE in Rectal Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Rectal Cancer|Defect of Floor of Lesser Pelvis
Interventions: PROCEDURE: Reconstruction with an acellular porcine dermal collagen implant (biological mesh)|PROCEDURE: Reconstruction with a gluteus maximus myocutaneous flap
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Distant Extrafascial Injection vs Subfascial Injection for Interscalene Block: Acute Pain Outcomes and Rates of Complications
Status: COMPLETED
Conditions: Ultrasound-guided Regional Anesthesia|Shoulder Surgery|Interscalene Block|Postoperative Analgesia|Respiratory Function
Interventions: PROCEDURE: Distant extrafascial injection|PROCEDURE: Subfascial injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Pharmacokinetics and Pharmacodynamics of JMI-001
Status: UNKNOWN
Conditions: Veisalgia
Interventions: DRUG: JMI-001|DRUG: Naproxen|DRUG: Fexofenadine|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Olanzapine, Haloperidol, Ziprasidone, Midazolam for Acute Undifferentiated Agitation
Status: COMPLETED
Conditions: Agitation,Psychomotor
Interventions: DRUG: Haloperidol Injection|DRUG: Ziprasidone Injection|DRUG: OLANZapine Injection|DRUG: Midazolam injection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical Trial of Coenzyme Q10 and Lisinopril in Muscular Dystrophies
Status: COMPLETED
Conditions: Duchenne Muscular Dystrophy|Becker Muscular Dystrophy|Limb Girdle Muscular Dystrophy
Interventions: DRUG: Coenzyme Q10 and Lisinopril
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Learn More About the Safety of Damoctocog-alfa-pegol When Used in Routine Medical Care in Korean Participants With Hemophilia A
Status: RECRUITING
Conditions: Hemophilia A|Prophylaxis of Bleeding|Treatment of Bleeding
Interventions: DRUG: Damoctocog-alfa-pegol (Jivi, BAY94-9027)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: CROS Application in CI
Status: COMPLETED
Conditions: Hearing Loss
Interventions: DEVICE: Phase I - Standard Microphone Cros Input|DEVICE: Phase II - Automatic directional microphone Cros Input|DEVICE: Phase III - No Cros Input
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Inhibition of Bradykinin in COVID-19 Infection With Icatibant
Status: COMPLETED
Conditions: SARS CoV 2 Infection
Interventions: DRUG: Icatibant|DRUG: 0.9% Sodium Chloride Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Real-Time Atherosclerosis Activity After Thoracic Radiotherapy Using Sodium Fluoride Positron Emission Tomography
Status: NOT_YET_RECRUITING
Conditions: Oligometastatic Disease
Interventions: DIAGNOSTIC_TEST: 18-F-NaF Cardiac PET/MRI and|DIAGNOSTIC_TEST: CT Angiogram
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Evaluate Pharmacokinetics and Safety of PF-06700841 After Single and Multiple Oral Doses as Modified Release Formulations
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DRUG: PF-06700841 IR|DRUG: PF-06700841 MR1|DRUG: PF-06700841 MR2|DRUG: PF-06700841 MR3|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Comparison of Low and Intermediate Dose Low-molecular-weight Heparin to Prevent Recurrent Venous Thromboembolism in Pregnancy
Status: COMPLETED
Conditions: Deep Venous Thrombosis|Pulmonary Embolism
Interventions: DRUG: Low dose nadroparin|DRUG: Intermediate dose nadroparin|DRUG: Low dose enoxaparin|DRUG: Intermediate dose enoxaparin|DRUG: Low dose dalteparin|DRUG: Intermediate dose dalteparin|DRUG: Fixed low dose tinzaparin|DRUG: Intermediate dose tinzaparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of Mavorixafor in Participants With Congenital and Acquired Primary Autoimmune and Idiopathic Chronic Neutropenic Disorders Who Are Experiencing Recurrent and/or Serious Infections
Status: RECRUITING
Conditions: Neutropenia
Interventions: DRUG: Mavorixafor|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Persistence of Anti-meningococcal Bactericidal Antibodies Among Adolescents Who Previously Received MenACWY Conjugate Vaccine
Status: COMPLETED
Conditions: Meningococcal Meningitis
Interventions: BIOLOGICAL: MenACWY-CRM conjugate vaccine|BIOLOGICAL: Licensed comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Sedative Effect and Safety of Remimazolam Besylate in ARDS Patients
Status: RECRUITING
Conditions: Respiratory Distress Syndrome
Interventions: DRUG: Remazolam besylate|DRUG: midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Community-Based Lifestyle Intervention for Diabetes Prevention in Arab Women
Status: RECRUITING
Conditions: Diabetes|Health Behaviors
Interventions: BEHAVIORAL: Attention-control|BEHAVIORAL: Community based intervention with resilience training|BEHAVIORAL: intervention-HPP|BEHAVIORAL: Pilot
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Transcatheter Arterial Chemoembolization With KMG Microsphere Treating Advance-stage Hepatocellular Carinomas (TACE-KMG)
Status: UNKNOWN
Conditions: Carcinoma, Hepatocellular
Interventions: OTHER: Therapeutic Chemoembolization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy and Interferon Alfa Followed by Surgery and/or Radiation Therapy in Treating Patients With Stage I, Stage II, or Stage III Esophageal Cancer
Status: TERMINATED
Conditions: Esophageal Cancer
Interventions: BIOLOGICAL: recombinant interferon alfa|DRUG: cisplatin|DRUG: fluorouracil|DRUG: hydroxyurea|DRUG: leucovorin calcium|PROCEDURE: conventional surgery|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Prospective Study on Feto-maternal outcoMe In aNemIc womEn
Status: ACTIVE_NOT_RECRUITING
Conditions: Anemia|Pregnancy Anemia|Pregnancy Bleeding|Transfusion-dependent Anemia|Transfusion; Embolism, Thrombus|Bleeding|Placenta Diseases
Interventions: DIAGNOSTIC_TEST: iron deficiency, coagulation abnormalities
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p