pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Safety Study of Parathyroid Hormone in Patients Needing Additional Stem Cell Mobilization.
Status: COMPLETED
Conditions: Lymphoma|Multiple Myeloma|Acute Myelogenous Leukemia
Interventions: DRUG: Stem cell mobilization
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mental Practice Versus Proprioceptive Neuromuscular Facilitation on Strength of Upper Limb
Status: WITHDRAWN
Conditions: Motor Activity
Interventions: PROCEDURE: mental practice|PROCEDURE: proprioceptive neuromuscular facilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Trazodone for SSRI-sexual Dsyfunction
Status: COMPLETED
Conditions: Sexual Dysfunction
Interventions: DRUG: Trazodone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Influence of Insertion Torque and Bone Type on Post-operative Pain
Status: COMPLETED
Conditions: Postoperative Pain|Postsurgical Pain|Dental Implant Failed
Interventions: PROCEDURE: Implant insertion
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bendamustine, Obinutuzumab, and Venetoclax in Patients With Untreated Mantle Cell Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: CCND1 Positive|Mantle Cell Lymphoma|t(11;14) Positive
Interventions: DRUG: Bendamustine|BIOLOGICAL: Obinutuzumab|DRUG: Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Specialised Paediatric Palliative Care
Status: COMPLETED
Conditions: Paediatric Palliative Care
Interventions: OTHER: Specialised Paediatric Palliative Care (SPPC)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Efficacy of Low Dose of Proton Pump Inhibitor in Treatment Bleeding Ulcers
Status: COMPLETED
Conditions: Gastroduodenal Ulcer|Marginal Ulcer|Peptic Ulcer Hemorrhage
Interventions: DRUG: Omeprazole 40 MG
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase III Study on the Safety, Pharmacokinetics and Efficacy of Coagulation Factor VIIa
Status: COMPLETED
Conditions: Hemophilia A With Inhibitors|Hemophilia B With Inhibitors
Interventions: BIOLOGICAL: Coagulation FVIIa (Recombinant)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acute Study to Evaluate a Novel Implantable Midfield Powered Device in Humans With Urinary Incontinence
Status: COMPLETED
Conditions: Overactive Bladder
Interventions: DEVICE: AHLeveeS System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Intravenous Magnesium Sulfate Vs Placebo to Treat Non -Traumatic Acute Headaches in the Emergency Department
Status: RECRUITING
Conditions: Head Pain
Interventions: DRUG: Magnesium sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Respiratory Impact of LA Volume After IS Block
Status: COMPLETED
Conditions: Arthroscopic Surgery of the Shoulder|Extrafascial Interscalene Plexus Brachial Block
Interventions: DRUG: Ropivacaine 0.75% Injectable Solution|DRUG: Ropivacaine 0.75% Injectable Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacodynamic Profile of SPD489 in Healthy Adult Males Undergoing a Nocturnal Period of Acute Sleep Loss
Status: COMPLETED
Conditions: Sleep Deprivation
Interventions: DRUG: SPD489 20 mg|DRUG: SPD489 50 mg|DRUG: SPD489 70 mg|DRUG: Armodafinil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Endoscopic Assisted Electrochemotherapy in Addition to Neoadjuvant Treatment of Locally Advanced Rectal Cancer
Status: UNKNOWN
Conditions: Locally Advanced Rectal Cancer|Electrochemotherapy|Neoadjuvant Therapy|Down Staging
Interventions: DRUG: Electrochemotherapy with bleomycin|DEVICE: EndoVE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dose Response Relationship for Single Doses of Corticotropin Releasing Hormone (CRH) in Normal Volunteers and in Patients With Adrenal Insufficiency
Status: COMPLETED
Conditions: Adrenal Gland Hyperfunction|Adrenal Gland Hypofunction|Cushing's Syndrome|Healthy
Interventions: DRUG: Ovine Corticotropin-Releasing Hormone (oCRH)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of Telitacicept in Lupus Nephritis
Status: RECRUITING
Conditions: Lupus Nephritis
Interventions: BIOLOGICAL: Telitacicept 240 mg|BIOLOGICAL: Telitacicept 160 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Interventions to De-implement Unnecessary Antibiotic Prescribing for Children With Ear Infections
Status: NOT_YET_RECRUITING
Conditions: Acute Otitis Media|Ear Infection|Pediatric Infectious Disease
Interventions: OTHER: Changes to the electronic health record (EHR)|OTHER: Individualized audit and feedback reporting for clinicians|OTHER: Clinician education sessions|OTHER: Use of a shared decision-making (SDM) aide|OTHER: Shared decision-making (SDM) education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Effectiveness of Oral Health Promotion on Pneumonia Complicating Stroke
Status: COMPLETED
Conditions: Stroke|Pneumonia|Oral Hygiene
Interventions: OTHER: Advanced oral hygiene care programme|OTHER: Oral hygiene instruction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Improvement of the Safety of Care in Cataract Surgery Teaching on Eyesi Simulator (E3CAPS)
Status: RECRUITING
Conditions: Surgery-Complications|Cataract
Interventions: OTHER: Eyesi simulator|OTHER: Sleep deprivation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Optimizing Self-Monitoring Feedback for the Treatment of Obesity
Status: ENROLLING_BY_INVITATION
Conditions: Obesity|Weight Loss
Interventions: BEHAVIORAL: Component 1: Calorie Goal Attainment|BEHAVIORAL: Component 2: Diet Quality|BEHAVIORAL: Component 3: Physical Activity Goal Attainment|BEHAVIORAL: Component 4: Goal Setting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Extension to a Study on the Efficacy and Safety of Vildagliptin in Combination With Glimepiride in Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: vildagliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Impact of Patient Education on Preoperative Anxiety and Postoperative Psychosocial Outcomes
Status: UNKNOWN
Conditions: Preoperative Anxiety
Interventions: BEHAVIORAL: Virtual education|BEHAVIORAL: Contact education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Thalidomide Prevention or Treatment of Camrelizumab-induced Reactive Cutaneous Capillary Endothelial Proliferation (RCCEP)
Status: RECRUITING
Conditions: Lung Cancer, Nonsmall Cell|Esophageal Carcinoma
Interventions: DRUG: Camrelizumab|DRUG: Thalidomide 50mg|DRUG: Thalidomide 100mg|DRUG: Thalidomide 200mg|DRUG: Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PredIcting sterOid depeNdEnt livEr injuRy With Polyreactive Immunoglobulin G
Status: RECRUITING
Conditions: Autoimmune Hepatitis|Autoimmune Liver Disease
Interventions: DIAGNOSTIC_TEST: polyreactive immunoglobulin G
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Clinical Study of TQH2929 in Healthy Adult Subjects
Status: RECRUITING
Conditions: Psoriasis
Interventions: DRUG: TQH2929 injection|DRUG: Placebo injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Effect of 12-week Dietary Supplementation With a Multicomponent Nutritional Supplement on Nails and Skin
Status: COMPLETED
Conditions: Nail Damage
Interventions: OTHER: Multicomp|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Combination Chemotherapy With or Without Gemtuzumab Ozogamicin or Tipifarnib in Treating Patients With Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndromes
Status: COMPLETED
Conditions: Leukemia|Myelodysplastic Syndromes
Interventions: BIOLOGICAL: alemtuzumab|DRUG: arsenic trioxide|DRUG: azacitidine|DRUG: busulfan|DRUG: clofarabine|DRUG: cytarabine|DRUG: daunorubicin hydrochloride|DRUG: fludarabine phosphate|DRUG: gemtuzumab ozogamicin|DRUG: melphalan|DRUG: tipifarnib|GENETIC: DNA methylation analysis|GENETIC: cytogenetic analysis|GENETIC: gene expression analysis|GENETIC: mutation analysis|OTHER: diagnostic laboratory biomarker analysis|OTHER: immunologic technique|PROCEDURE: allogeneic hematopoietic stem cell transplantation|PROCEDURE: nonmyeloablative allogeneic hematopoietic stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: A Study to Learn if Recombinant Human Parathyroid Hormone [rhPTH(1-84)] Can Improve Symptoms and Metabolic Control in Adults With Hypoparathyroidism (BALANCE)
Status: COMPLETED
Conditions: Hypoparathyroidism
Interventions: BIOLOGICAL: rhPTH (1-84)|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Evaluate the Safety and Efficacy of "Theobromine Capsule" as an Antitussive in Acute Cougher
Status: COMPLETED
Conditions: Acute Bronchitis
Interventions: DRUG: Theobromine 300mg|DRUG: Levodropropizine 10mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sperm Quality in Consecutive Sperm Samples After 4-7 Days and 2 Hours of Sexual Abstinence
Status: COMPLETED
Conditions: Semen Quality
Interventions: OTHER: 2-7 days of Sexual abstinence|OTHER: 2 hours of sexual abstinence
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Clinical Trial Comparing Noradrenaline (NA) Plus Placebo Versus Noradrenaline Plus Terlipressin (TP) in Septic Shock
Status: RECRUITING
Conditions: Septic Shock
Interventions: COMBINATION_PRODUCT: Noradrenaline plus Terlipressin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dexmedetomidine Versus Midazolam for Facilitating Extubation
Status: COMPLETED
Conditions: Critical Illness
Interventions: DRUG: Midazolam|DRUG: Dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Probiotic Regimen on Vancomycin Resistant Enterococcus Intestinal Carriage
Status: UNKNOWN
Conditions: Vancomycin Resistant Enterococcus Intestinal Carriage
Interventions: DRUG: Lactobacillus casei rhamnosus (strain Lcr 35 LC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose:
Clinical trial: Combination of Gemcitabine, Oxaliplatin, Sintilimab and Bevacizumab in Unresectable Biliary Tract Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Biliary Tract Carcinoma|Initially Unresectable
Interventions: DRUG: Combination of Gemcitabine, Oxaliplatin, Sintilimab and Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EFFECT OF PRE EXTUBATION MANUAL HYPERINFLATION TECHNIQUE VS REGULAR EXTUBATION AFTER STERNOTOMY
Status: COMPLETED
Conditions: Sternotomy
Interventions: PROCEDURE: Extubation|PROCEDURE: Manual Hyperinflation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of KP104 to Treat Glomerulonephritis
Status: NOT_YET_RECRUITING
Conditions: Glomerulonephritis
Interventions: DRUG: KP104
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Peanut Ball Use on Labor
Status: COMPLETED
Conditions: Birth Outcome, Adverse|Birth, First|Labor Long|Apgar; 4-7 at 1 Minute
Interventions: OTHER: The Effect of Peanut Ball Use on Labor Memory, Labor Satisfaction, Delivery Length, and Neonatal APGAR Score: A Randomized Controlled Trial
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Clinical Study to Evaluate the Treatment Effect and Safety of BAY1817080 in Patients With Overactive Bladder (OAB)
Status: COMPLETED
Conditions: Overactive Bladder
Interventions: DRUG: Placebo|DRUG: BAY1817080
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Efficacy of Intravenous Esketamine in Adult Patients With Treatment-Resistant Depression
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: Esketamine|DRUG: Esketamine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of the Jamboxx Respiratory Therapy Device: Study 2
Status: WITHDRAWN
Conditions: Cystic Fibrosis in Children
Interventions: DEVICE: Jamboxx Respiratory Therapy Device|OTHER: Autogenic Draining Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment the Activity Value of Isotretinoin (13- Cis-Retinoic Acid ) in the Treatment of COVID-19 ( Isotretinoin in Treatment of COVID-19) (Randomized)
Status: UNKNOWN
Conditions: COVID19
Interventions: DRUG: Drug Isotretinoin (13 cis retinoic acid ) capsules+standard treatment|DRUG: Isotretinoin(Aerosolized 13 cis retinoic acid) +standard treatment|DRUG: Isotretinoin (13 cis retinoic acid ) capsules|DRUG: Aerosolized 13 cis retinoic acid|DRUG: Standard treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of Pantoprazole on the Bioavailability of MMF and EC-MPS
Status: COMPLETED
Conditions: Transplantation|Immunosuppression|Drug Interaction
Interventions: DRUG: Mycophenolate sodium|DRUG: Pantoprazole|DRUG: Mycophenolate mofetil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CD19-CAR Immunotherapy for Childhood Acute Lymphoblastic Leukemia (ALL)
Status: TERMINATED
Conditions: Acute Lymphoblastic Leukemia
Interventions: GENETIC: donor-derived EBV-specific cytotoxic T-cells (EBV-CTL) transduced with the retroviral vector SFGalpha-CD19-CD3zeta|BIOLOGICAL: Irradiated donor-derived Lymphoblastoid Cell Line
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multimodal Remote Monitoring and Integrated Educational Program in OSA Patients Initiating Continuous Positive Airway Pressure (CPAP): (SLEEPCONNECT)
Status: TERMINATED
Conditions: Obstructive Sleep Apnea Syndrome
Interventions: OTHER: CPAP associated with connected devices: blood pressure monitor , scales and activity monitor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Investigating the Postprandial Glucose Metabolism After Treatment With Faster-acting Insulin Aspart in Subjects With Type 1 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 1
Interventions: DRUG: Faster-acting insulin aspart|DRUG: insulin aspart
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Using Two Different Construction Techniques of Nasoalveolar Molding Devices in Unilateral Cleft Lip and Palate Patients
Status: ENROLLING_BY_INVITATION
Conditions: Unilateral Cleft Lip and Palate
Interventions: OTHER: Nasoalveolar molding device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Conscious Sedation for Cataract Operations Under Topical Anaesthesia
Status: COMPLETED
Conditions: Conscious Sedation
Interventions: DRUG: Nalbuphine|DRUG: Propofol|DRUG: Dexmedetomidine|DRUG: Benoxinate Hydrochloride 0.4% Eye Drops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Thumb Basal Joint (CMC I) Arthritis - Preoperative Anxiety/Depression, Outcome Instruments, Carpal Cinematics and Cost-utility
Status: RECRUITING
Conditions: Arthritis|Thumb Osteoarthritis|Arthropathy|Quality of Life
Interventions: PROCEDURE: Trapeziectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study To Assess The Safety And Tolerability Of GSK189075 When Given With A Total Daily Dose Of >/ 2000mg of Metformin
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: GSK189075|DRUG: Metformin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prednisolone Versus Colchicine for Acute Gout in Primary Care
Status: RECRUITING
Conditions: Acute Gout
Interventions: DRUG: Prednisolone 30 mg Tablet|DRUG: Colchicine 0.5 mg Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Agreements Between Transcutaneous and Arterial Monitoring of Oxygen and Carbon Dioxide After Non-cardiac Surgery
Status: UNKNOWN
Conditions: Post Anesthesia Care Optimaization
Interventions: DEVICE: TCM-5 Flex monitor connected to a Sensor 84 (Radiometer Medical Aps, Brønshøj, Denmark)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Postoperative Immobilization and Physical Therapy Following Volar Locked Plating for Distal Radius Fractures
Status: RECRUITING
Conditions: Distal Radius Fracture
Interventions: OTHER: Splint|BEHAVIORAL: Formal Physical Therapy|BEHAVIORAL: Self directed physical therapy|OTHER: Soft dressing (No Splint)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effectiveness of Montelukast in Children With Recurrent Obstructive Bronchitis
Status: UNKNOWN
Conditions: Acute Bronchiolitis
Interventions: DRUG: Montelukast Sodium|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Xingnaojing for Moderate-to-severe Acute Ischemic Stroke (XMAS)
Status: UNKNOWN
Conditions: Acute Ischemic Stroke
Interventions: DRUG: Xingnaojing injection|OTHER: Standard care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CD19 and BCMA Targeted Fast Dual CAR-T for CD19+ Refractory/Relapsed B-NHL
Status: WITHDRAWN
Conditions: B-cell Lymphoma
Interventions: BIOLOGICAL: Fast Dual CAR-T Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparative Study of Selatogrel (ACT-246475) Formulations in Healthy Subjects
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: COMBINATION_PRODUCT: Selatogrel|DRUG: Selatogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Efficacy of Low Dose Propofol Given at the End of Sevoflurane Anesthesia for Prevention of Emergence Agitation in Pediatric Patient Undergoing MRI Scan
Status: NOT_YET_RECRUITING
Conditions: Emergence Agitation
Interventions: DRUG: Propofol|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of the Use of Xylitol Gum in the Prevention of Caries Lesions in Children Living in Ladakh
Status: UNKNOWN
Conditions: Caries
Interventions: DIETARY_SUPPLEMENT: Administration of sugar-free gums sugar-free gums containing 100% Xylitol as sweetener|DIETARY_SUPPLEMENT: Administration of sugar-free gums sugar-free gums containing containing a polyols mixture plus a low amount of Xylitol (22%)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Long-Term HEAD START Training on Surgical Skill Levels
Status: COMPLETED
Conditions: Trichiasis|Surgery
Interventions: OTHER: Long-Term HEAD START Training|OTHER: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Post-operative Urinary Retention (POUR) Following Thoracic Surgery
Status: RECRUITING
Conditions: Urinary Retention
Interventions: DRUG: Tamsulosin - 1 week|DRUG: Tamsulosin - 3 days
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Peripheral Nerve Blocks for Above-the-knee Amputations
Status: RECRUITING
Conditions: Peripheral Vascular Diseases|Hyperglycaemia (Diabetic)|Hypertension|Coronary Artery Disease|Pulmonary Disease, Chronic Obstructive
Interventions: PROCEDURE: Peripheral nerve block|DRUG: Intravenous Sedatives|PROCEDURE: Lateral femoral cutaneous nerve blocks|PROCEDURE: Obturator nerve blocks
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: JWCAR201 for the Treatment of Hematology Malignancy and Autoimmune Diseases
Status: NOT_YET_RECRUITING
Conditions: B-cell Tumors|Autoimmune Diseases|Lupus Erythematosus, Systemic|Large B-cell Lymphoma
Interventions: BIOLOGICAL: JWCAR201
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Olezarsen (ISIS 678354) in Participants With Hypertriglyceridemia and Atherosclerotic Cardiovascular Disease, or With Severe Hypertriglyceridemia
Status: ACTIVE_NOT_RECRUITING
Conditions: Hypertriglyceridemia|Cardiovascular Diseases|Atherosclerosis
Interventions: DRUG: Olezarsen|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multiple Breath Nitrogen Washout in Healthy and Cystic Fibrosis Adults
Status: COMPLETED
Conditions: Cystic Fibrosis|Healthy
Interventions: DEVICE: Comparison of two MBWN2 devices : "EasyOne Pro Lab" versus "Exhalyzer D"
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Home-Based Respiratory Muscle Strength Training Program for Individuals With Post-COVID-19 Persistent Dyspnea
Status: RECRUITING
Conditions: Post-COVID-19 Syndrome|Dyspnea
Interventions: DEVICE: Respiratory Muscle Strength Trainers
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Paclitaxel Plus Carboplatin With or Without SCH-58500 in Treating Patients With Newly Diagnosed Stage III Ovarian or Stage III Primary Peritoneal Cancer
Status: TERMINATED
Conditions: Ovarian Cancer|Primary Peritoneal Cavity Cancer
Interventions: BIOLOGICAL: recombinant adenovirus-p53 SCH-58500|DRUG: carboplatin|DRUG: paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Real-world Comparative Effectiveness of Stroke Prevention in Patients With Atrial Fibrillation Treated With Rivaroxaban vs. Vitamin k Antagonists
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DRUG: Rivaroxaban (Xarelto, BAY597939)|DRUG: Phenprocoumon (branded and generics)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pediatric Myocardial Protection With Potassium Cardioplegia
Status: COMPLETED
Conditions: Cardioplegia
Interventions: DRUG: Cold blood cardioplegia (large volume)|DRUG: Cold blood cardioplegia (small volume)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of 3 Versus 6-Month Use of CGMS in Non-Insulin Using T2DM Patients
Status: TERMINATED
Conditions: T2DM (Type 2 Diabetes Mellitus)|Continuous Glucose Monitoring
Interventions: DEVICE: iPro2 Professional CGM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Remifentanil Requirement for Acceptable Intubating Condition
Status: COMPLETED
Conditions: Intubating Condition
Interventions: DRUG: Ketamine 1|DRUG: Ketamine 2|DRUG: Remifentanil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Avelumab in Combination With Gemcitabine in Advanced Leiomyosarcoma as a Second-line Treatment
Status: UNKNOWN
Conditions: Leiomyosarcoma Metastatic
Interventions: DRUG: Avelumab and Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Concordance Between Central Blood PRessure dEvices In Nephrology Patients
Status: RECRUITING
Conditions: Hypertension|Chronic Kidney Disease|Blood Pressure
Interventions: DEVICE: Brachial and Central BP measurements with Mobil-o-Graph NG device (IEM), WatchBP Office device (Microlife), BP+ device (Uscom) and Oscar 2 with SphygmoCor inside device (SunTech)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of AzaSite Versus Vigamox Concentrations in the Conjunctiva and Aqueous Humor in Subjects Undergoing Routine Cataract Surgery
Status: COMPLETED
Conditions: Bacterial Infections|Eye Infections|Cataract Extraction
Interventions: DRUG: AzaSite Eye Drops|DRUG: Vigamox Eye Drops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy and Safety of Carfilzomib in Combination With Ibrutinib vs Ibrutinib in Waldenström's Macroglobulinemia
Status: RECRUITING
Conditions: Waldenstrom Macroglobulinemia
Interventions: DRUG: Carfilzomib + Ibrutinib|DRUG: Ibrutinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Injection Molded PEEK Framework and Cobalt Chromium Framework in Removable Partial Denture Regarding Retention
Status: UNKNOWN
Conditions: Mandibular Prosthesis User
Interventions: DEVICE: peek framework RPD|DEVICE: cobalt chromium framework RPD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment Study for Rural Latino Youth With Anxiety
Status: COMPLETED
Conditions: Anxiety Disorders|Separation Anxiety Disorder|Social Anxiety Disorder|Specific Phobia|Generalized Anxiety Disorder
Interventions: BEHAVIORAL: Therapist-Assisted by Telephone|BEHAVIORAL: Self-Help
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Total Mesorectal Excision(TME) With Lateral Lymph Node Dissection Versus TME After Neoadjuvant Chemo-radiotherapy
Status: RECRUITING
Conditions: Rectal Neoplasm Malignant
Interventions: PROCEDURE: TME+LLND|PROCEDURE: TME+nCRT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endobronchial Ultrasound Transbronchial Needle Aspiration Using Needle Suction Versus No Suction
Status: COMPLETED
Conditions: Mediastinal Lymphadenopathy|Lung Malignancies
Interventions: PROCEDURE: Endobronchial Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Studying Blood Samples From Patients With Multiple Myeloma Who Were Treated With Thalidomide or Lenalidomide
Status: COMPLETED
Conditions: Multiple Myeloma and Plasma Cell Neoplasm
Interventions: GENETIC: gene expression analysis|GENETIC: reverse transcriptase-polymerase chain reaction|OTHER: immunoenzyme technique|OTHER: laboratory biomarker analysis|OTHER: platelet aggregation test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Oral Morphine Versus Ibuprofen
Status: COMPLETED
Conditions: Upper Extremity Fractures|Analgesia Post Fracture
Interventions: DRUG: Oral morphine|DRUG: Ibuprofen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective Randomized Trial On RadiaTion Dose Estimates Of CT AngIOgraphy In PatieNts Scanned With A 100kV Protocol
Status: UNKNOWN
Conditions: Coronary Disease
Interventions: RADIATION: tube voltage|RADIATION: tube voltage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Effectiveness of Alzheimer's Universe (Www.AlzU.Org) on Knowledge and Behavior
Status: WITHDRAWN
Conditions: Alzheimer Disease|Alzheimer Disease, Late Onset|Memory Loss|Patient Education as Topic
Interventions: BEHAVIORAL: Web-based education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Ondanstron Weekly vs Every 3 Weeks for Prevention of Nausea and Vomiting Induced by Chemotherapy Combined With PD-1 Blockade
Status: RECRUITING
Conditions: Nausea With Vomiting Chemotherapy-Induced
Interventions: DRUG: Ondansetron every 3 weeks|DRUG: Aprepitant|DRUG: Dexamethasone|DRUG: Ondansetron weekly
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Development of a New Impedance Mapping System for Ablation of Atrial Arrhythmias in Patients
Status: UNKNOWN
Conditions: Atrial Fibrillation and Flutter|Atrial Arrhythmia|Atrial Fibrillation Recurrent
Interventions: DEVICE: cardioz mapping
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Efficacy of Skin Cleanser Contained Roselle Extract in Acne
Status: UNKNOWN
Conditions: Acne
Interventions: OTHER: skin cleanser contained Hibiscus sabdariffa extract|OTHER: marketed skin cleanser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of NUTRIOSE®FB Dietary Fiber Supplementation on Satiety, Body Fat, and Metabolic Syndrome in Overweight Adult Men
Status: COMPLETED
Conditions: Overweight|Metabolic Syndrome X
Interventions: DIETARY_SUPPLEMENT: NUTRIOSE|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Links Between Water and Salt Intake, Body Weight, Hypertension and Kidney Stones: a Difficult Puzzle
Status: UNKNOWN
Conditions: Urinary Stones|Hypertension|Overweight|Obesity
Interventions: DIETARY_SUPPLEMENT: low salt diet|DIETARY_SUPPLEMENT: water therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Therapy of Bosentan and Aerosolized Iloprost in Idiopathic Pulmonary Arterial Hypertension (IPAH)
Status: TERMINATED
Conditions: Hypertension
Interventions: DRUG: Aerosolized iloprost|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Passive Myofunctional Appliances for Snoring and Mild Obstructive Sleep Apnea
Status: RECRUITING
Conditions: Sleep Apnea, Obstructive
Interventions: DEVICE: passive myofunctional appliance|DEVICE: standard oral appliance
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial to Learn if Linvoseltamab is Safe and Works in Adults With Relapsed or Refractory Systemic Light Chain Amyloidosis (AL Amyloidosis)
Status: RECRUITING
Conditions: Relapsed/Refractory Systemic Light Chain Amyloidosis
Interventions: DRUG: Linvoseltamab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: NEXIUM® in the Treatment of Moderate and Severe Erosive Esophagitis
Status: COMPLETED
Conditions: Erosive Esophagitis|Reflux Esophagitis|Gastroesophageal Reflux Disease
Interventions: DRUG: esomeprazole magnesium (oral medication)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose:
Clinical trial: A Parent-child Yoga Intervention for Reducing Attention Deficits in Children With Congenital Heart Disease: A Feasibility Study
Status: RECRUITING
Conditions: Congenital Heart Disease|Child Development|Neurodevelopmental Disorders|Parents
Interventions: BEHAVIORAL: Parent-child yoga
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Clinical Trial to Compare Oral Isotretinoin to Standard of Care in Moderate Acne Skin of Color Patients
Status: NOT_YET_RECRUITING
Conditions: Acne Vulgaris
Interventions: DRUG: ISOtretinoin 5 MG|DRUG: Topical cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Use of Drospirenone/Estetrol in Random Start Rapid Endometrial Preparation
Status: COMPLETED
Conditions: Endometrial Polyp|Endometrial Diseases
Interventions: DRUG: drospirenone/estetrol 3mg/14.2mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Probiotic (LGG) for Veterans With PTSD
Status: RECRUITING
Conditions: Post Traumatic Stress Disorder|Inflammation
Interventions: BIOLOGICAL: Lactobacillus rhamnosus GG (LGG; ATCC strain 53103; CRMTS #11272; PTS #3766)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acute Kidney Injury Genomics and Biomarkers in TAVR Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Kidney Injury|Renal Insufficiency, Chronic|Heart Failure|Myocardial Infarction|Arrhythmias, Cardiac|Stroke
Interventions: PROCEDURE: Transcatheter Aortic Valve Replacement
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Randomized Controlled Trial of the Effectiveness of Group Treatment With War-Exposed Bosnian Adolescents
Status: COMPLETED
Conditions: Posttraumatic Stress Disorder|Depression|Grief (Traumatic Grief and Existential Grief)
Interventions: BEHAVIORAL: Trauma and Grief Component Therapy for Adolescents (Group Version)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Family-Directed Cognitive Adaptation Program for Individuals With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder|Schizophreniform Disorder
Interventions: BEHAVIORAL: Family-Directed Cognitive Adaptation Program
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of BMS-986012 in Combination With Carboplatin, Etoposide, and Nivolumab as First-line Therapy in Extensive-stage Small Cell Lung Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Extensive-stage Small Cell Lung Cancer
Interventions: BIOLOGICAL: BMS-986012|DRUG: Carboplatin|DRUG: Etoposide|BIOLOGICAL: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Follicular Steroid Genesis in Controlled Ovarian Stimulation
Status: COMPLETED
Conditions: Infertility|Controlled Ovarian Hyperstimulation
Interventions: DRUG: COS with GnRH antagonists and rFSH|DRUG: COS with GnRH antagonists and HP-HMG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Tolerance of Formula 609613 37 in Acneic Patients
Status: COMPLETED
Conditions: Acne
Interventions: OTHER: moisturizing cream and 5% benzoyl peroxide gel|OTHER: anti-acne face cream and 5% benzoyl peroxide gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: WallFlex Biliary Post Liver Transplant IDE Pilot
Status: COMPLETED
Conditions: Anastomotic Biliary Stricture Post Orthotopic Liver Transplant
Interventions: DEVICE: WallFlex Biliary Fully Covered Stent
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Palmitic Acid in the Sn-2 Position of Triacylglycerols and Postprandial Lipemia
Status: COMPLETED
Conditions: Healthy Men|Raised Fasting Plasma Triacylglycerol Concentrations
Interventions: DIETARY_SUPPLEMENT: High-fat meal containing native palm olein|DIETARY_SUPPLEMENT: High-fat meal containing interesterified palm olein
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study to Evaluate Resiniferatoxin in Patients With Knee Osteoarthritis Whose Total Knee Replacement Surgery is Delayed
Status: WITHDRAWN
Conditions: Osteoarthritis, Knee|Osteo Arthritis Knee|Knee Pain Chronic
Interventions: DRUG: Resiniferatoxin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Selective Serotonin Reuptake Inhibitors (SSRIs) in Borderline Personality Disorder
Status: TERMINATED
Conditions: Borderline Personality Disorder
Interventions: DRUG: Escitalopram
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of ICON Treatment on WPL With Patients After Fixed Orthodontic Appliances
Status: UNKNOWN
Conditions: White Spot Lesion
Interventions: DRUG: ICON Remineralization|DRUG: CPP-ACPF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prolotherapy Versus Steroids for Thumb Carpo-metacarpal Joint Arthritis
Status: TERMINATED
Conditions: Thumb Carpometacarpal Joint Osteoarthritis
Interventions: DRUG: Prolotherapy (10% dextrose solution)|DRUG: Betamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Relevance of Reversible Causes During OHCA (Rebecca Study)
Status: RECRUITING
Conditions: Out-Of-Hospital Cardiac Arrest|Cardiopulmonary Arrest
Interventions: DIAGNOSTIC_TEST: Checklist for evaluation of reversible causes
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Use of Mentoring to Promote Well-being for Female SMART Members
Status: ACTIVE_NOT_RECRUITING
Conditions: Harassment, Non-Sexual|Harassment, Sexual|Bullying, Workplace|Mental Stress|Work-Related Condition|Work-related Injury|Work Related Stress
Interventions: BEHAVIORAL: Mentoring program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study of RVT-1401 in Myasthenia Gravis (MG) Patients
Status: COMPLETED
Conditions: Myasthenia Gravis
Interventions: DRUG: RVT-1401|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hypomethylating Agents and Venetoclax in Newly Diagnosed Acute Myeloid Leukemia Patients Not Eligible for Intensive Chemotherapy
Status: UNKNOWN
Conditions: Acute Myeloid Leukemia, Adult|Hypomethylating Agents|Venetoclax
Interventions: DRUG: Venetoclax
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study to Assess Safety and Tolerability of AG013 in Oral Mucositis in Subjects Receiving Induction Chemotherapy for the Treatment of Cancers of the Head and Neck
Status: COMPLETED
Conditions: Oral Mucositis
Interventions: BIOLOGICAL: AG013|BIOLOGICAL: AG013|BIOLOGICAL: AG013|OTHER: Placebo|OTHER: Placebo|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: Characteristics of (Unwanted) Use of Alcohol and Illicit Substances Among Patients Reporting After Sexual Violence in Ghent: a Mono-centric Prospective Observational Study
Status: RECRUITING
Conditions: Drug-facilitated Sexual Assault
Interventions: DIAGNOSTIC_TEST: urine/blood analysis with IA and LC-GCMS analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Cannabinoids and Biological Reactivity to Stress
Status: NOT_YET_RECRUITING
Conditions: Cannabis Use Disorder
Interventions: DRUG: Hydrocortisone Oral|DRUG: Yohimbine Hydrochloride|DRUG: Cornstarch Placebo 20mg|DRUG: Cornstarch Placebo 54mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Soft Tissue Esthetic With Autogenous Dentin Chips and Immediate Implantation Versus Conventional Immediate Implantation With Xenograft in Thin Buccal Bone
Status: COMPLETED
Conditions: Crestal Bone Loss
Interventions: PROCEDURE: immediate implant with dentine chips|PROCEDURE: conventional immediate implant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: NEXT: Subsequent Exposure to Tyrosine Kinase Inhibition at Recurrence After Adjuvant Therapy in Renal Cell Carcinoma
Status: TERMINATED
Conditions: Renal Cell Carcinoma
Interventions: DRUG: Axitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gastric Emptying Following an Oral Carbohydrate Load in Women Admitted for Elective Cesarean Delivery
Status: TERMINATED
Conditions: Pregnancy|Respiratory Aspiration of Gastric Contents
Interventions: DIETARY_SUPPLEMENT: Cranberry juice
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Natriuretic Peptide System in African-Americans.
Status: COMPLETED
Conditions: Healthy|Prehypertension
Interventions: DIETARY_SUPPLEMENT: Low-Salt Diet|DIETARY_SUPPLEMENT: High-Salt Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH