pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Comparison of Five-year Survival and Disease-free Survival in Patients Diagnosed With Endometrium Cancer Who Underwent Total Laparoscopic Hysterectomy With and Without Uterine Manipulator
Status: RECRUITING
Conditions: Endometrial Cancer
Interventions: PROCEDURE: Patients Diagnosed With Endometrium Cancer Who Underwent Total Laparoscopic Hysterectomy With manipulator|PROCEDURE: lPatients Diagnosed With Endometrium Cancer Who Underwent Total Laparoscopic Hysterectomy without uterine manipulator
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effects of Hydrocortisone in Endotoxemia in Normal Volunteers
Status: COMPLETED
Conditions: Infections
Interventions: BIOLOGICAL: Endotoxin, Lipopolysaccharide, LPS|BIOLOGICAL: Endotoxin, Lipopolysaccharide, LPS /Epinephrine|BIOLOGICAL: Placebo|BIOLOGICAL: Hydrocortisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Organoids Predict Therapeutic Response in Patients With Multi-line Drug-resistant Lung Cancer
Status: RECRUITING
Conditions: Lung Cancer|Organoid
Interventions: DRUG: Antitumor therapy guided by organoid drug sensitivity test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Behavior Therapy for Children and Adolescents With Obsessive-Compulsive Disorder (OCD)
Status: COMPLETED
Conditions: Obsessive-Compulsive Disorder
Interventions: BEHAVIORAL: Exposure and Response Prevention|BEHAVIORAL: Family Treatment Program|BEHAVIORAL: Relaxation Training|BEHAVIORAL: Behavior therapy|BEHAVIORAL: Family Counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Silent Myocardial Ischemia in Patients Undergoing Non-oncological Abdominal Surgeries
Status: RECRUITING
Conditions: Silent Myocardial Ischemia|Acute Myocardial Infarction
Interventions: GENETIC: Silent myocardial ischemia, STEMI
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Herombopag Olamine in the Treatment of Thrombocytopenia After Chemotherapy
Status: RECRUITING
Conditions: Malignant Tumors of the Digestive System|Trombocitopenia
Interventions: DRUG: Hetrombopag Olamine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Long-term Efficacy and Mechanisms Underlying the Impact of a Web-based Sexual and Relationship Health Promotion Program With Young Adult Community College Students
Status: COMPLETED
Conditions: Sexual Behavior|Sexual Assault|Violence, Domestic
Interventions: BEHAVIORAL: Media Aware for Young Adults|BEHAVIORAL: Health Aware for Young Adults
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Reversal With Sugammadex From Deep Neuromuscular Blockade Induced by Rocuronium in Children: Randomised Clinical Trial
Status: COMPLETED
Conditions: Neuromuscular Blockade
Interventions: DRUG: Sugammadex|DRUG: Neostigmine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Arterial Cannulation on the Continuous and Non-invasive Hemoglobin Monitoring
Status: COMPLETED
Conditions: Gastric Cancer
Interventions: OTHER: arterila cannulation on same arm|OTHER: arterila cannulation on different arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Prehabilitation in Rectal Cancer: During Neoadjuvant Therapy vs Preoperative
Status: NOT_YET_RECRUITING
Conditions: Rectal Cancer, Adenocarcinoma|Chemoradiotherapy
Interventions: BEHAVIORAL: prehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Assessing the Performance of Wesper Lab for Sleep Apnea Diagnosis in Pediatric Populations
Status: NOT_YET_RECRUITING
Conditions: Sleep Apnea|Sleep Apnea Syndromes in Children|Sleep Apnea Syndromes
Interventions: DEVICE: Medical Device: Wesper Lab Home Sleep Test
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: LS301-IT in Partial Mastectomy and Sentinel Lymph Node Biopsy (SLNB) for DCIS or Stage I-II Primary Invasive Breast Cancer
Status: RECRUITING
Conditions: Breast Cancer|DCIS|Invasive Duct Carcinoma of Breast
Interventions: DRUG: LS301-IT 0.025 mg/kg|DRUG: LS301-IT 0.05 mg/kg|DRUG: LS301-IT 0.075 mg/kg|DRUG: LS301-IT 0.1 mg/kg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vaccine Therapy in Treating Patients With Stage III or Stage IV Ovarian Epithelial Cancer
Status: TERMINATED
Conditions: Ovarian Cancer
Interventions: BIOLOGICAL: BCG vaccine|BIOLOGICAL: autologous tumor cell vaccine|DRUG: carboplatin|DRUG: cisplatin|DRUG: cyclophosphamide|DRUG: paclitaxel|OTHER: dinitrophenyl|PROCEDURE: surgical procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Interdisciplinary Rehabilitation of Patients With Glioma During Anti-cancer Treatment
Status: COMPLETED
Conditions: Neoplasms|CNS Neoplasms
Interventions: BEHAVIORAL: Interdisciplinary rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of Tempol to Prevent Hair Loss From Radiotherapy to the Brain
Status: UNKNOWN
Conditions: Alopecia
Interventions: DRUG: 7% (w/v) Tempol alcohol-based gel (MTS-01)|DRUG: alcohol-based gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Phase I Study Evaluating SCB-313(Recombinant Human TRAIL-Trimer Fusion Protein) for the Treatment of Malignant Pleural Effusion
Status: COMPLETED
Conditions: Malignant Pleural Effusion
Interventions: DRUG: SCB-313
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Comparison of the Airway Devices
Status: COMPLETED
Conditions: Endotracheal Intubation|Supraglottic Airway
Interventions: DEVICE: LTS-D|DEVICE: ProSeal Laryngeal Mask Airway|DEVICE: Esophageal Tracheal Combitube (ETC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Subject Treatment Preference Study of Tivozanib Versus Sunitinib in Subjects With Metastatic RCC
Status: TERMINATED
Conditions: Metastatic Renal Cell Carcinoma
Interventions: DRUG: Tivozanib|DRUG: Sunitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Arthroplasty and Modifiable Risk Factors
Status: COMPLETED
Conditions: Total Joint Arthroplasty|Risk Reduction|Surgical Site Infection|Prosthetic-joint Infection|Postoperative Complications
Interventions: OTHER: Early preoperative assessment and optimization
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Double-Blind, Randomized, Placebo-Controlled Study Evaluating the Effects of Bardoxolone Methyl on Body Composition in Patients With Stage 4 Chronic Kidney Disease and Type 2 Diabetes Mellitus
Status: WITHDRAWN
Conditions: Renal Insufficiency, Chronic|Diabetes Mellitus, Type 2
Interventions: DRUG: Bardoxolone Methyl|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: TACE+RFA Versus Re-resection for Recurrent Small Hepatocellular Carcinoma
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma|Surgery|Ablation
Interventions: PROCEDURE: TACE+RFA|PROCEDURE: re-resection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assess Bronchodilator Effect and Safety of Two Doses of QVM149 Compared to a Fixed Dose Combination of Salmeterol/Fluticasone in Patients With Asthma.
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: QVM149 150/50/80 μg o.d.|DRUG: QVM149 150/50/160 μg o.d.|DRUG: salmeterol/fluticasone FDC 50/500 μg b.i.d.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Follow-up Survey to Compare Stable Dosing (SERETIDE) With SYMBICORT, SMART, Maintenance and Reliever Therapy in One Inhaler in Moderate and Severe Asthmatics.
Status: COMPLETED
Conditions: Asthma
Interventions: OTHER: Spirometry, PEF measurements and diary cards to evaluate control of Asthma
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized Controlled Study of High-dose Cyclophosphamide Induction Therapy in Adult Patients With HLH
Status: RECRUITING
Conditions: Hemophagocytic Syndrome
Interventions: DRUG: Cytoxan|DRUG: Etoposide|DRUG: Dexamethasone|DRUG: Cyclosporine (CSA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Experimental Test of Facebook Social Drinking Norms on Adolescent Alcohol Use
Status: COMPLETED
Conditions: Feedback, Psychological|Underage Alcohol Use|Risk-Taking
Interventions: BEHAVIORAL: Abstainer|BEHAVIORAL: Abstainer + User|BEHAVIORAL: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Spinal Cord Transcutaneous Stimulation Effect on Blood Pressure in Acute Spinal Cord Injury (SCI)
Status: RECRUITING
Conditions: Spinal Cord Injuries|Spinal Cord Diseases|Trauma, Nervous System|Nervous System Diseases|Central Nervous System Diseases|Hypotension|Orthostatic Hypotension|Cardiovascular Diseases|Acute Spinal Cord Injury|Blood Pressure
Interventions: DIAGNOSTIC_TEST: Orthostatic challenge|DEVICE: Biostim-5 transcutaneous spinal stimulation - Mapping|DEVICE: Biostim-5 transcutaneous spinal stimulation - "Optimal" testing|DEVICE: Biostim-5 transcutaneous spinal stimulation - "Sham" testing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Melatonin Treatment for Newborn Infants With Moderate to Severe Hypoxic Ischemic Encephalopathy
Status: WITHDRAWN
Conditions: Newborn Hypoxic Ischemic Encephalopathy
Interventions: DRUG: Melatonin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Adding Cytokines to In Vitro Human Culture Media to Improve Embryogenesis and Implantation
Status: COMPLETED
Conditions: Infertility
Interventions: OTHER: Adding LIF, HB-EGF and GM-CSF to Lifeglobal human IVF culture media
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Conversion From MPA to Zortress (Everolimus) for GI Toxicity Post-renal Transplantation
Status: TERMINATED
Conditions: Kidney Transplant Rejection|Gastrointestinal Disorder, Functional
Interventions: DRUG: Everolimus|DRUG: Mycophenolic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Apatinib Mesylate Combined With IT Regimen for the Treatment of Recurrent or Refractory Pediatric Neuroblastoma
Status: RECRUITING
Conditions: Neuroblastoma
Interventions: DRUG: Apatinib, Irinotecan, Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CompuFlo Thoracic Epidural Study
Status: COMPLETED
Conditions: Thoracic Epidural Anesthesia
Interventions: DEVICE: Traditional (loss-of-resistance technique) thoracic epidural placement|DEVICE: CompuFlo thoracic epidural placement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy in Treating Patients With Small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DRUG: carboplatin|DRUG: etoposide|DRUG: ifosfamide|DRUG: topotecan hydrochloride|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Less Invasive Detection and Treatment of Very Early Coronary Artery Disease in Patients With Diabetes Mellitus
Status: UNKNOWN
Conditions: Type 2 Diabetes|Microvascular Dysfunction
Interventions: OTHER: Intensive risk factor management
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Total Marrow and Lymphoid Irradiation Before Donor Transplant and Cyclophosphamide in Treating Patients With Acute Myeloid Leukemia
Status: RECRUITING
Conditions: Acute Myeloid Leukemia
Interventions: PROCEDURE: Allogeneic Hematopoietic Stem Cell Transplantation|DRUG: Cyclophosphamide|BIOLOGICAL: Filgrastim|OTHER: Laboratory Biomarker Analysis|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration|DRUG: Tacrolimus|RADIATION: Total Marrow Irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Skin-to-skin Contact During the Transfer From the Delivery Room to the Neonatal Intensive Care Unit: Impact on Very Preterm Infants and Their Parents
Status: NOT_YET_RECRUITING
Conditions: Skin to Skin|Premature Newborns
Interventions: PROCEDURE: Skin-to-skin Contact (SSC)|PROCEDURE: Incubator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Phase III Study Testing Efficacy & Safety of Oral Dabigatran Etexilate vs Warfarin for 6 m Treatment for Acute Symp Venous Thromboembolism (VTE)
Status: COMPLETED
Conditions: Thromboembolism
Interventions: DRUG: Warfarin|DRUG: Dabigatran etexilate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Randomized, Double-Blind, Active Control Trial Comparing Effects of Telmisartan, Candesartan and Amlodipine, Alone or Plus Metformin, on Non-Diabetic, Obese Hypertensive Patients
Status: COMPLETED
Conditions: Hypertension|Obesity
Interventions: DRUG: Telmisartan plus Metformin|DRUG: Telmisartan|DRUG: Candesartan|DRUG: Candesartan plus Metformin|DRUG: Amlodipine|DRUG: Amlodipine plus Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Exploring Brain Damages After COVID-19 Infection
Status: COMPLETED
Conditions: SARS-CoV 2
Interventions: PROCEDURE: Auditory Evoked Potentials (AEP)|PROCEDURE: Blink and Masseter Inhibitory Reflex
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Clinical Study of the Effect of Intravenous Galactose on Diabetic Macular Oedema
Status: TERMINATED
Conditions: Diabetic Macular Oedema
Interventions: DRUG: Galactose, intravenous
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Methylene Blue Intravenously and Chronic Neuropathic Pain
Status: COMPLETED
Conditions: Neuropathic Pain
Interventions: DRUG: Methylene blue|DRUG: Methylene blue
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Long-term Safety of TAK-771 in Japanese Primary Immunodeficiency Disease (PID) Participants
Status: ACTIVE_NOT_RECRUITING
Conditions: Primary Immunodeficiency Diseases (PID)
Interventions: DRUG: TAK-771
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Pharmacokinetics of Multiple Rising Doses of Ixazomib in Lupus Nephritis (LN)
Status: TERMINATED
Conditions: Lupus Nephritis
Interventions: DRUG: Ixazomib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Compare the Safety and Pharmacokinetics of CKD-330 8/5mg With Coadministration of the Two Separate Drugs
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Candesartan 8mg|DRUG: Amlodipine 5mg|DRUG: CKD-330 8/5mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Personalized Follow-up After Breast Cancer Surgery Via Electronic Patient Reported Outcomes
Status: COMPLETED
Conditions: Breast Cancer
Interventions: OTHER: Collection of postoperative information|OTHER: Analysis of postoperative information collected from patients
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Live Zoster Vaccine in HIV-Infected Adults on Antiretroviral Therapy
Status: COMPLETED
Conditions: Herpes Zoster|HIV Infections
Interventions: BIOLOGICAL: ZOSTAVAX|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: First-in-human Trial of Home Brain Pressure Measured Using Kitea ICP Sensor, Placed During Hydrocephalus Shunt Surgery.
Status: RECRUITING
Conditions: Hydrocephalus
Interventions: DEVICE: Kitea ICP Sensor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adebrelimab Combined With SOX Regimen in Preoperative Neoadjuvant Transformation Therapy for Locally Advanced Gastric Adenocarcinoma
Status: RECRUITING
Conditions: Locally Advanced Gastric Adenocarcinoma
Interventions: DRUG: Adebrelimab combined with SOX regimen|DRUG: Placebo combined with SOX (S-1/oxaliplatin) regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Inositol and Omega-3 Fatty Acids in Pediatric Mania
Status: COMPLETED
Conditions: Pediatric Bipolar Spectrum Disorders
Interventions: DRUG: Omega-3|DRUG: Inositol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Optimal Long Term Treatment Strategy of Anti-resorptive Medications---The Extension of Denosumab Sequential Therapy
Status: RECRUITING
Conditions: Osteoporosis|Bone Mineral Density
Interventions: DRUG: Denosumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Xenon for Neuroprotection During Post-Cardiac Arrest Syndrome in Comatose Survivors of an Out of Hospital Cardiac Arrest
Status: UNKNOWN
Conditions: Post-Cardiac Arrest Syndrome
Interventions: COMBINATION_PRODUCT: Xenon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study in Healthy Male Volunteers to Look at How the Test Medicine GLPG1690 is Taken up by the Body When Given by Mouth and Into a Vein as an Injection
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: GLPG1690 film-coated tablets|DRUG: [14C]-GLPG1690 solution for infusion|DRUG: [14C]-GLPG1690 capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Investigating the Effect of Art Therapy on Women With Fear of Childbirth During Pregnancy: A Mixed Method Study
Status: RECRUITING
Conditions: Fear of Childbirth|Pregnancy Related|Anxiety and Fear|Anxiety|Fear
Interventions: OTHER: Art Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ursodeoxycholic Acid Plus Budesonide Versus Ursodeoxycholic Acid Alone in Primary Biliary Cirrhosis (PBC)
Status: TERMINATED
Conditions: Primary Biliary Cirrhosis
Interventions: DRUG: budesonide|DRUG: budesonide placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Manual vs. Spontaneous Removal of the Placenta at Cesarean Section
Status: COMPLETED
Conditions: Pregnancy|Cesarean Section
Interventions: PROCEDURE: Manual placental removal at Cesarean delivery|PROCEDURE: Spontaneous placental removal at Cesarean delivery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Socializing a Science-Based Digital Therapeutic for Substance Use Disorders
Status: RECRUITING
Conditions: Substance Use Disorders|Substance-Related Disorders
Interventions: BEHAVIORAL: Laddr® plus Behavioral- Group and individual counseling|BEHAVIORAL: Behavioral- Group and individual counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immune Changes Following Trabectedin in Patients With Metastatic or Unresectable Sarcoma
Status: WITHDRAWN
Conditions: Myxoid Liposarcoma|Round Cell Liposarcoma|Stage III Soft Tissue Sarcoma AJCC v7|Stage IV Soft Tissue Sarcoma AJCC v7|Metastatic Soft Tissue Sarcoma|Unresectable Soft Tissue Sarcoma
Interventions: PROCEDURE: Biopsy|OTHER: Laboratory Biomarker Analysis|DRUG: Trabectedin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Assess the Intrapulmonary Pharmacokinetics (PK) of SPR719 by Comparing the Plasma, Epithelial Lining Fluid, and Alveolar Macrophage Concentrations Following the Oral Administration of Multiple Doses of SPR720 in Healthy Volunteers.
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: SPR720
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 177Lu-AB-3PRGD2 in Patients With Integrin αVβ3 Positive Tumors
Status: RECRUITING
Conditions: Integrin αVβ3 Positive Tumors
Interventions: DRUG: 1.48 GBq of 177Lu-AB-3PRGD2
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Scintigraphy Study to Assess Nasal Deposition of Ciclesonide. Using a Novel Nasal Metered Dose Inhaler
Status: COMPLETED
Conditions: Allergic Rhinitis (AR)
Interventions: DRUG: ciclesonide nasal aerosol|DRUG: mometasone Aqueous (AQ) nasal spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 3 Study of TG103 Injection Combined With Metformin in Treatment of Type 2 Diabetes Mellitus
Status: NOT_YET_RECRUITING
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: TG103|DRUG: Dulaglutide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Striving Towards EmPowerment and Medication Adherence R01
Status: RECRUITING
Conditions: Hiv|Mental Health Issue
Interventions: BEHAVIORAL: STEP-AD|BEHAVIORAL: Enhanced treatment as usual (E-TAU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Gentle Gymnastics and Relationship Between Family Caregivers and Residents With Dementia in Nursing Homes
Status: COMPLETED
Conditions: Dementia|Relation, Family
Interventions: OTHER: Tai Chi inspired gymnastics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Natalizumab in Recurrent, Refractory or Progressive Pulmonary Metastatic Osteosarcoma
Status: RECRUITING
Conditions: Pulmonary Metastatic Osteosarcoma (pOS)
Interventions: DRUG: Natalizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SAFEty and Efficacy of HOME-based Hospitalization Versus Inpatient Care for Patients With Acute Heart Failure in Chronic Heart Failure.
Status: TERMINATED
Conditions: Heart Failure
Interventions: PROCEDURE: HOME-based hospitalization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low-Level EMF Stimulation for Paroxysmal Atrial Fibrillation
Status: COMPLETED
Conditions: Atrial Fibrillation|Catheter Ablation|Autonomic Imbalance
Interventions: DEVICE: Low-level Pulsed EMF|DEVICE: Sham Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bemotrizinol UV Filter Part 1 Clinical PK Evaluation in Topical MUsT Study
Status: COMPLETED
Conditions: Absorption; Chemicals|Sunscreening Agents
Interventions: DRUG: Bemotrizinol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Silver Diamine Fluoride and Gingivitis in Geriatric Patients
Status: COMPLETED
Conditions: Gingivitis
Interventions: DEVICE: Silver Diamine Fluoride|OTHER: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Accelerated Bilateral Sequential Theta Burst Stimulation in Older Adults With Treatment-resistant Depression
Status: RECRUITING
Conditions: Depressive Disorder, Treatment-Resistant
Interventions: DEVICE: active accelerated bilateral sequential theta burst stimulation and sham treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multimodal Molecular Targeted Therapy to Treat Relapsed or Refractory High-risk Neuroblastoma
Status: COMPLETED
Conditions: Neuroblastoma Recurrent
Interventions: DRUG: Dasatinib|DRUG: Rapamycin|DRUG: Irinotecan|DRUG: Temozolomide|DRUG: Irinotecan|DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of an Anti-TRPM8 in the Atopic Dermatitis Pruritus
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: OTHER: Adding menthoxypropanediol to the biopsy|OTHER: No adding menthoxypropanediol to the biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Free Fatty Acids-Induced Hypertension in Obese Subjects (Aim #2)
Status: COMPLETED
Conditions: Hypertension|Diabetes
Interventions: DRUG: Salsalate|DRUG: Carvedilol|DRUG: Placebo|DRUG: Intralipid 20%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of Intravenous EEDVsMit in Children With Recurrent / Refractory Solid or CNS Tumours Expressing EGFR
Status: TERMINATED
Conditions: Solid Tumours|CNS Tumours
Interventions: DRUG: Mitoxantrone packaged EDV (EnGeneIC Delivery Vehicle)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Measurements of Inflammation Induced by Allergen Inhalation Challenge in Mild Allergic Asthma
Status: NOT_YET_RECRUITING
Conditions: Mild Asthma
Interventions: DIAGNOSTIC_TEST: Allergen challenge|DIAGNOSTIC_TEST: Saline challenge
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: MAGNETISMM-2: Study of Elranatamab (PF-06863135) in Japanese Participants With Multiple Myeloma
Status: UNKNOWN
Conditions: Relapsed or Refractory Multiple Myeloma
Interventions: DRUG: Elranatamab (PF-06863135)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ernährungs-Interventions-Fettleber-Studie (Interventional Study on Nutritional Effects on NAFLD)
Status: UNKNOWN
Conditions: NAFLD|Obesity|Prediabetes|Dyslipoproteinemia
Interventions: DIETARY_SUPPLEMENT: Dietary intervention / counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of Oral Acyclovir in the Treatment of Molluscum Contagiosum in Children
Status: UNKNOWN
Conditions: Molluscum Contagiosum
Interventions: DRUG: Acyclovir|DRUG: KOH 10 %
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Language Intervention Study of Preterm Infants
Status: UNKNOWN
Conditions: Language Development|Language Delay|Mother-Infant Interaction|Maternal Behavior
Interventions: BEHAVIORAL: Reading intervention|BEHAVIORAL: Infant bonding|BEHAVIORAL: LENA recording|BEHAVIORAL: LENA linguistic feedback|BEHAVIORAL: LENA summary
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Sleep Deprivation Reduces Tear Secretion and Impairs the Tear Film
Status: COMPLETED
Conditions: We Investigated the Effect of Sleep Deprivation on the Tear Film and Ocular Surface.
Interventions: BEHAVIORAL: sleep deprivation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effect of BPA on Anchor Antibiotic Continuity in the ED: Randomized Controlled Trial
Status: COMPLETED
Conditions: Infections, Bacterial|Sepsis|Alert Fatigue, Health Personnel
Interventions: OTHER: Epic Best Practice Alert
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Investigation Into an Innovative, Clinical Slip Inducing Device in the Chronic Incomplete Spinal Cord Population
Status: ACTIVE_NOT_RECRUITING
Conditions: Spinal Cord Injuries
Interventions: DEVICE: Slip Training
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Clinical Trial to Evaluate the Effects of a Nutraceutical in Patients Affected by Knee Osteoarthritis
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: DIETARY_SUPPLEMENT: SYALOX® 300 Plus|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Oral Vitamin D Supplement on Atopic Dermatitis; A Clinical Trial With Staphylococcus Aureus Colonization Determination
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: oral vitamin D|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating 13-Valent Pneumococcal Conjugate Vaccine (13vPnC) In Healthy Infants In China
Status: COMPLETED
Conditions: Pneumococcal Infection
Interventions: BIOLOGICAL: 7-valent Pneumococcal Conjugate Vaccine|BIOLOGICAL: 13-valent Pnumococcal Conjugate vaccine|BIOLOGICAL: 13-valent Pnumococcal Conjugate vaccine|BIOLOGICAL: 13-valent Pnumococcal Conjugate vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Phase II Study of Gemcitabine+Romidepsin in the Relapsed/Refractory Peripheral T-cell Lymphoma Patients
Status: COMPLETED
Conditions: Peripheral T-cell Lymphoma
Interventions: DRUG: Romidepsin + Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Haloperidol With or Without Chlorpromazine in Treating Delirium in Patients With Advanced, Metastatic, or Recurrent Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Malignant Neoplasm|Delirium|Locally Advanced Malignant Neoplasm|Metastatic Malignant Neoplasm|Recurrent Malignant Neoplasm
Interventions: DRUG: Chlorpromazine|DRUG: Haloperidol|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: T Lymphocytes (LT) Expressing iCASP9 and ΔCD19 in Allogeneic Haematopoietic Transplantation.
Status: UNKNOWN
Conditions: Graft Versus Host Disease|Hematological Malignancies
Interventions: DRUG: T lymphocytes iCASP9 ΔCD19|DRUG: Dimerizer drug AP1903
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effects of Regular Mountain Hiking on Hopelessness in Chronically Suicidal Patients
Status: COMPLETED
Conditions: Suicide|Hopelessness
Interventions: OTHER: Mountain hiking in the Austrian and Bavarian Alps
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Cognition Following Computer Assisted Total Knee Arthroplasty
Status: COMPLETED
Conditions: Cognition|Embolism, Fat
Interventions: DEVICE: Total Knee Arthroplasty Implant (Scorpio®)|DEVICE: Total Knee Arthroplasty Implant (Scorpio®)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Biomarkers in DNA Samples From Patients With High-Risk Acute Lymphoblastic Leukemia
Status: COMPLETED
Conditions: Leukemia
Interventions: GENETIC: DNA analysis|GENETIC: genetic linkage analysis|GENETIC: microarray analysis|GENETIC: nucleic acid sequencing|GENETIC: polymerase chain reaction|GENETIC: polymorphism analysis|OTHER: laboratory biomarker analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Ulipristal Versus Placebo for Women With Bleeding Induced by Mirena
Status: UNKNOWN
Conditions: Heavy Menstrual Bleeding|Abnormal Bleeding
Interventions: DRUG: Ulipristal acetate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of (1) Everolimus, (2) Estrogen Deprivation Therapy (EDT) With Leuprolide + Letrozole and (3) Everolimus + EDT in Patients With Unresectable Fibrolamellar Hepatocellular Carcinoma (FLL-HCC)
Status: COMPLETED
Conditions: Fibrolamellar Carcinoma|Fibrolamellar Liver Cancer
Interventions: DRUG: everolimus|DRUG: letrozole plus leuprolide|DRUG: combination of everolimus, letrozole and leuprolide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bintrafusp Alfa in Previously Treated Patients With R/M Non-keratinizing NPC
Status: COMPLETED
Conditions: Nasopharyngeal Carcinoma|Recurrent Carcinoma|Metastatic Cancer|Non-keratinizing Carinoma
Interventions: DRUG: Bintrafusp Alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial Investigating the Pharmacodynamics of BC Combo THDB0207 Compared With Humalog® Mix25 and Simultaneous Injections of Humalog® and Lantus® in Healthy Chinese Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Euglycemic clamp with BC Combo THDB0207|DRUG: Euglycemic clamp with Humalog® Mix25|DRUG: Euglycemic clamp with Humalog® and Lantus®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparisons of Intravenous Ceftriaxone With Intravenous Moxifloxacin in ERCP
Status: COMPLETED
Conditions: Cholangitis
Interventions: DRUG: Moxifloxacin|DRUG: ceftriaxone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Dose Finding Study of ADVM-043 Gene Therapy to Treat Alpha-1 Antitrypsin (A1AT) Deficiency
Status: COMPLETED
Conditions: Alpha 1-Antitrypsin Deficiency
Interventions: GENETIC: ADVM-043
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Vitamin C and E on Endothelial Function in Adolescent Diabetes
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus
Interventions: DIETARY_SUPPLEMENT: Vitamin C|DIETARY_SUPPLEMENT: Vitamin E
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single and Multiple Dose Escalation Study to Assess the Safety and Tolerability of CJM112 in Psoriasis
Status: COMPLETED
Conditions: Chronic Plaque-type Psoriasis
Interventions: BIOLOGICAL: CJM112|BIOLOGICAL: Secukinumab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Interaction Between Nevirapine and Saquinavir-sgc in HIV-1 Infected Patients
Status: TERMINATED
Conditions: HIV Infections
Interventions: DRUG: Nevirapine|DRUG: Saquinavir-sgc
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of SHJ002 Ophthalmic Solution in the Treatment of Corneal Erosion in Sjogren's Patients
Status: RECRUITING
Conditions: Corneal Erosion
Interventions: DRUG: SHJ002|OTHER: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Rubidium PET and SPECT With CZT Crystals for Detection of Myocardial Ischemia in Overweighed Patients and Women
Status: COMPLETED
Conditions: Myocardial Ischemia
Interventions: RADIATION: Rubidium PET
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Pectoral Nerve Block for Analgesia After Breast Augmentation
Status: COMPLETED
Conditions: Ambulatory Plastic Surgery|Esthetic Prosthetic Breast Expansion
Interventions: DRUG: Ropivacaine after dilution with sodium chloride 0.9%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Role of Dietary Habits in Efficacy of Bariatric Surgery - Study C
Status: ACTIVE_NOT_RECRUITING
Conditions: Bariatric Surgery|Sleeve Gastrectomy|Obesity
Interventions: BEHAVIORAL: Dietary habits plan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison the Safety and Pharmacokinetic Characteristics of DWP422 25 mg With Those of ENBREL 25MG PFS INJ. After Subcutaneous Injection in Healthy Male Volunteers
Status: UNKNOWN
Conditions: Rheumatoid Arthritis
Interventions: DRUG: DWP422 25mg|DRUG: ENBREL 25MG PFS INJ.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE|Primary Purpose:
Clinical trial: Induction Chemotherapy and Chemoradiotherapy in Nasopharyngeal Cancers
Status: TERMINATED
Conditions: Nasopharyngeal Cancers
Interventions: PROCEDURE: Induction chemotherapy + concurrent radiochemotherapy vs. concurrent radiochemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 6% Hydroxyethyl Starch (130/0.4) Coload for Postspinal Anesthesia Hypotension
Status: RECRUITING
Conditions: Adverse Effect
Interventions: DRUG: Hydroxyethyl starch 130/0.4
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Evaluate Safety and Efficacy of Cell Therapy in Patients With Cicatricial Conjuntivitis.
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Conjunctivitis|Stevens-Johnson Syndrome|Lyell Syndrome|Pemphigoid
Interventions: DRUG: Single Dose|DRUG: Double Dose
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dietary and Cognitive Effects of Food Ads Posted by TikTok Influencers
Status: RECRUITING
Conditions: Calorie Consumption
Interventions: BEHAVIORAL: TikTok Ads - With Food|BEHAVIORAL: TikTok Ads - Without Food
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Pasta and Bread Prepared With Durum Wheat Semolina: Effect on Post-prandial Glucose and Insulin Metabolism
Status: COMPLETED
Conditions: Dietary Modification
Interventions: OTHER: Short pasta (dry)|OTHER: Long pasta (dry)|OTHER: Bread|OTHER: Glucose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Neuromodulation Implantation Settings Variation for Overactive Bladder
Status: WITHDRAWN
Conditions: Overactive Bladder
Interventions: DEVICE: Intermittent or Continuous Setting RestorePrime Implanted Impulse Generator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Preventing Gastrointestinal Disturbance in Patients After Longitudinal Laparotomy.
Status: RECRUITING
Conditions: Ileus Postoperative
Interventions: DRUG: ORE001|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of the Cuff Pressure of a Taper-guard Cuffed Tube Between Ipsilateral and Contralateral Rotation of Head
Status: COMPLETED
Conditions: Anesthesia, Endotracheal|Airway Management
Interventions: PROCEDURE: Ipsilateral rotation of head|PROCEDURE: Contralateral rotation of head
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Study of the Paclitaxel-Coated Balloon Catheter in Bifurcated Coronary Lesions
Status: UNKNOWN
Conditions: Coronary Artery Disease
Interventions: PROCEDURE: Balloon angioplasty|PROCEDURE: Stent implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sex Differences in the effecTs of brEaking uP Sedentary Behavior on vascUlar Function in Type 2 Diabetes
Status: RECRUITING
Conditions: Type 2 Diabetes|Cardiovascular Diseases
Interventions: BEHAVIORAL: prolonged SB|BEHAVIORAL: SB broken 1|BEHAVIORAL: SB broken 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Gemcitabine and Epirubicin in Treating Patients With Malignant Mesothelioma
Status: COMPLETED
Conditions: Malignant Mesothelioma
Interventions: DRUG: epirubicin hydrochloride|DRUG: gemcitabine hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intermittent Fasting Using a Fasting-Mimicking Diet to Improve Prostate Cancer Control and Metabolic Outcomes
Status: RECRUITING
Conditions: Prostate Adenocarcinoma
Interventions: BEHAVIORAL: Fasting Mimicking Diet (FMD)|BEHAVIORAL: Standard Anti-Cancer Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long-term Observational Study of Subjects From Tanezumab Studies Who Undergo a Total Knee, Hip or Shoulder Replacement
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DRUG: Investigational Medical Product (IMP) administered in parent study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Combination Chemotherapy Plus Bevacizumab in Treating Patients With Advanced Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: BIOLOGICAL: bevacizumab|DRUG: fluorouracil|DRUG: irinotecan hydrochloride|DRUG: leucovorin calcium
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT