pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Study of Forodesine Hydrochloride in Patients With Relapsed/Refractory Precursor T-Lymphoblastic Leukemia/Lymphoma Who Have Failed Two or More Prior Treatment Regimens
Status: TERMINATED
Conditions: Leukemia|Lymphoma
Interventions: DRUG: Forodesine Hydrochloride Sterile Solution, 5 mg/mL|DRUG: Forodesine Hydrochloride Capsules (100 mg)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Fractional Carbon Dioxide Laser Treatment for Female Stress Urinary Incontinence
Status: RECRUITING
Conditions: Stress Urinary Incontinence
Interventions: PROCEDURE: Fractional carbon dioxide laser treatment|PROCEDURE: Fractional carbon dioxide laser sham treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Mucinex and IR Guaifenesin the Treatment of Symptoms of Acute Upper Respiratory Tract Infections
Status: COMPLETED
Conditions: Acute Upper Respiratory Tract Infection
Interventions: DRUG: Mucinex|DRUG: Immediate-release Guaifenesin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of the DANUBIO Paclitaxel Eluting Balloon in Side Branches of de Novo Bifurcation Lesions (DEBSIDE)
Status: COMPLETED
Conditions: Coronary Disease
Interventions: DEVICE: Danubio paclitaxel-eluting balloon
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Intravenous Mircera for the Correction of Anemia in Dialysis Patients.
Status: COMPLETED
Conditions: Anemia
Interventions: DRUG: methoxy polyethylene glycol-epoetin beta [RO0503821, Mircera]|DRUG: Epoetin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Study the Efficacy and Safety of TIPS (Trans Intrahepatic Portosystemic Shunt) Versus Self Expanding Metallic Stent (SEMS) in the Management of Refractory Variceal Bleed in Cirrhotics.
Status: UNKNOWN
Conditions: Liver Cirrhoses
Interventions: PROCEDURE: Trans Intrahepatic Portosystemic Shunt|PROCEDURE: Self Expanding Metallic Stent|DRUG: Vasoactive Agent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mindful Construal Diaries: Can the MCD Increase Mindfulness and Mindful Eating in Bariatric Surgery Patients
Status: COMPLETED
Conditions: Obesity
Interventions: BEHAVIORAL: Mindful Construal Diary
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy of Small Bowel Preparation in Capsule Endoscopy
Status: COMPLETED
Conditions: Gastrointestinal Bleedings
Interventions: DRUG: Standard diet|DRUG: Standard Diet + 500 ml of polyethyleneglycol|DRUG: Standard diet + 2 liters of polyethylene glycol the day before + 500ml of polyethylene glycol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Percutaneous Nephrolithotomy in Patients With Stage 2-4 Chronic Kidney Disease
Status: UNKNOWN
Conditions: Percutaneous Nephrolithotomy
Interventions: PROCEDURE: Percutaneous nephrolithotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bortezomib in Treating Patients With Newly Diagnosed Multiple Myeloma
Status: COMPLETED
Conditions: Stage I Multiple Myeloma|Stage II Multiple Myeloma|Stage III Multiple Myeloma
Interventions: DRUG: bortezomib|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: AMG 761 in Adults With Asthma
Status: TERMINATED
Conditions: Asthma
Interventions: DRUG: AMG 761|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Change of Hemodynamics and Cerebral Functions After Carotid Artery Revascularization
Status: RECRUITING
Conditions: Carotid Artery Diseases|Carotid Artery Stenosis|Cerebrovascular; Disorder, Arteriosclerotic|Cardiovascular Diseases|Nervous System Diseases
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety, Tolerability, and Immunogenicity of V114 Compared to Prevnar 13™ in PPSV23-vaccinated Healthy Adults ≥65 Years of Age (V114-007)
Status: COMPLETED
Conditions: Pneumococcal Infections
Interventions: BIOLOGICAL: V114|BIOLOGICAL: Prevnar 13™
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Repigmentation of Stable Vitiligo Lesions Using Spray-On Skin™ Cells
Status: ACTIVE_NOT_RECRUITING
Conditions: Vitiligo
Interventions: DEVICE: RECELL® Autologous Cell Harvesting Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Outcome of Pulpotomy Versus Root Canal Therapy
Status: RECRUITING
Conditions: Caries|Pulpitis - Irreversible
Interventions: PROCEDURE: Non surgical root canal treatment|PROCEDURE: Pulpotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: ZD1839 (Iressa™) In Combination With Docetaxel As First-Line Treatment In Patients With Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Gefitinib|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Diffusion MRI for Head and Neck Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Head Cancer Neck
Interventions: RADIATION: PET/MRI with FDG|RADIATION: MRI scan without contrast|RADIATION: MRI with gadolinium
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Fully Covered Self-expandable Metal Stents (FCMS) in Benign Biliary Strictures
Status: COMPLETED
Conditions: Biliary Stricture
Interventions: DEVICE: Placement of a FCMS in the biliary tract of the patients
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of S (+) - Ibuprofen in the Treatment of Mechanical Low Back Pain
Status: COMPLETED
Conditions: Low Back Pain, Mechanical|Low Back Pain|Acute Low Back Pain
Interventions: DRUG: S (+) - Ibuprofen|DRUG: Ibuflex®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety and Efficacy of CTP-543 in Adults With Moderate to Severe Alopecia Areata
Status: COMPLETED
Conditions: Alopecia Areata
Interventions: DRUG: CTP-543|DRUG: CTP-543 matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Drug-drug Interaction Study Between BMS-663068 and Oral Contraceptives in Healthy Female Volunteers (DDI)
Status: COMPLETED
Conditions: Infection, Human Immunodeficiency Virus
Interventions: DRUG: BMS-663068|DRUG: Oral Contraceptive|DRUG: Loestrin 1.5/30
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ability of a Euglena Beta Glucan Supplementation to Augment Immune Function
Status: COMPLETED
Conditions: Symptoms Flu|Symptoms Cold
Interventions: DIETARY_SUPPLEMENT: Whole Cell Euglena containing Beta Glucan|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Supra-Annular vs. Annular ValvEs for Small Annuli
Status: ENROLLING_BY_INVITATION
Conditions: Aortic Valve Stenosis|Implantation, Heart Valve Prosthesis
Interventions: DEVICE: Transcatheter aortic valve replacement (Edwards Sapien Ultra or Medtronic Evolut Pro
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Safety and Efficacy of OPC-64005 in the Treatment of Adult Attention-deficit/Hyperactivity Disorder
Status: COMPLETED
Conditions: Adult Attention Deficit Hyperactivity Disorder
Interventions: DRUG: OPC-64005|DRUG: Atomoxetine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Consistency Evaluation of the qCON, qNOX Indices and Bispectral Index
Status: COMPLETED
Conditions: Anesthesia Monitor|Electroencephalography|Sleep
Interventions: OTHER: Bispectral index and qCON/qNOX monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Biafine Cream to Reduce Side Effects of Radiation Therapy in Patients Receiving Treatment for Advanced Head and Neck Cancer
Status: COMPLETED
Conditions: Head and Neck Cancer|Skin Reactions Secondary to Radiation Therapy
Interventions: DRUG: Biafine cream|PROCEDURE: quality-of-life assessment|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety Study of GSK Biologicals' Human Papillomavirus Vaccine in 580299/008 Subjects From Brazil, Taiwan or Thailand
Status: COMPLETED
Conditions: Infections, Papillomavirus
Interventions: BIOLOGICAL: GSK580299, GSK Biological's HPV vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Ketamine as Adjunctive Analgesic With Bupivacaine in Paravertebral Analgesia for Breast Cancer Surgery
Status: COMPLETED
Conditions: Acute Pain|Chronic Pain
Interventions: DRUG: paravertebral block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Iron and Folic Acid on Skin Fungal Pattern in Patients With Arsenicosis
Status: COMPLETED
Conditions: Chronic Arsenic Poisoning
Interventions: DRUG: Placebo|DRUG: Iron 150 mg and Folic acid 0.5 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Decitabine Versus Supportive Care in Adults With Advanced-stage MDS
Status: COMPLETED
Conditions: Myelodysplastic Syndrome
Interventions: DRUG: decitabine (5-aza-2'deoxycytidine)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of a Cocoa Shot on the Human Brain
Status: COMPLETED
Conditions: Caffeine|Flavonoids
Interventions: DIETARY_SUPPLEMENT: High Caffeine|DIETARY_SUPPLEMENT: Low caffeine|DIETARY_SUPPLEMENT: High theobromine|DIETARY_SUPPLEMENT: low theobromine|DIETARY_SUPPLEMENT: No theobromine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Evolocumab in Functional Status and LDL Oxidation of Patients With Peripheral Arterial Disease
Status: UNKNOWN
Conditions: Peripheral Arterial Disease
Interventions: DRUG: Evolocumab 140 mg/mL Subcutaneous Injection 1 milliliter (mL) pre-filled injector Pen x 3 for a monthly dose of 420 mg for 6 months.|OTHER: Placebo 1milliliter (mL) Subcutaneous Injection pre-filled injector Pen x 3 monthly for 6 months.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Piezo-surgery Technique and Intramuscular Dexamethasone Injection to Reduce Postoperative Pain After Impacted Mandibular Third Molar Surgery
Status: COMPLETED
Conditions: Impacted Mandibular Third Molar Extraction
Interventions: DRUG: Dexamethasone injection|PROCEDURE: Piezosurgery|PROCEDURE: Conventional Rotatory instruments
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Hemodynamic Effects and Efficacy of Intramuscular PDA-002 in Subjects Who Have Diabetic Foot Ulcer With Peripheral Arterial Disease
Status: WITHDRAWN
Conditions: Diabetic Foot|Peripheral Arterial Disease
Interventions: DRUG: PDA-002|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Food Study of Paroxetine Hydrochloride Controlled-Release Tablets 25 mg to Paxil CR™ Tablets 25 mg
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Paroxetine Hydrochloride Controlled-Release Tablets 25 mg|DRUG: Paxil CR™ Tablets 25 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study to Evaluate the Effect of Yoga Exercises and Meditation on Lung Function and Quality of Life in COPD Patients.
Status: UNKNOWN
Conditions: COPD|Obstructive Pulmonary Disease
Interventions: OTHER: Yoga breathing exercises and Meditation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Preliminary Helicobacter Pylori Eradication After Multiple Doses of TNP-2198 Capsules Combined With Rabeprazole Sodium Enteric-coated Tablets, or Rabeprazole Sodium Enteric-coated Tablets and Amoxicillin Capsules
Status: COMPLETED
Conditions: Helicobacter Pylori Infection
Interventions: DRUG: TNP-2198|DRUG: Rabeprazole Sodium|DRUG: Amoxicillin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Tadalafil in Men With Benign Prostatic Hyperplasia Symptoms Who Are Being Treated With Alpha Blockers
Status: COMPLETED
Conditions: Benign Prostatic Hyperplasia
Interventions: DRUG: Tadalafil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Myocardial Deformation Before and After Birth
Status: ACTIVE_NOT_RECRUITING
Conditions: Myocardial Dysfunction|Newborn Morbidity|Maternal Obesity
Interventions: DRUG: Blood transfusion, Ibuprofen, or epinephrine, norepinephrine or dopamine
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect Of Medical Nutritional Therapy On Patients With Sarcopenic Obesity Receiving Peritoneal Dialysis Treatment
Status: COMPLETED
Conditions: Peritoneal Dialysis Complication|Sarcopenic Obesity
Interventions: OTHER: medical nutrition therapy in kidney diseases
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dairy Fat and Fermentation Study
Status: RECRUITING
Conditions: Heart Diseases|Microbial Colonization|Inflammation
Interventions: OTHER: Milk or yogurt beverage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SORT-OUT V - Randomised Clinical Comparative Study of the Nobori and the Cypher Stent.
Status: COMPLETED
Conditions: Coronary Artery Disease|Angina Pectoris
Interventions: PROCEDURE: Percutaneous coronary intervention (PCI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High Dose Buprenorphine (BUP) Induction in the Emergency Department (ED)
Status: RECRUITING
Conditions: Opioid Use Disorder
Interventions: DRUG: High Dose Buprenorphine|DRUG: Standard Buprenorphine Dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: C1 Esterase Inhibitor in Hereditary Angioedema (HAE)(Extension Study)
Status: COMPLETED
Conditions: Hereditary Angioedema
Interventions: DRUG: C1 Esterase Inhibitor
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Coenzyme Q10 in Huntington's Disease (HD)
Status: TERMINATED
Conditions: Huntington's Disease
Interventions: DRUG: coenzyme Q10|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Nitric Oxide in Cardiopulmonary Bypass for Renal Protection in Cardiac Surgery
Status: COMPLETED
Conditions: Coronary Artery Disease|Heart Valve Diseases|Cardiomyopathies|Acute Kidney Injury
Interventions: DRUG: Nitric Oxide|OTHER: Standard CPB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Phase 2 Study of Rituximab-ABVD in Classical Hodgkin Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: DRUG: Bleomycin|BIOLOGICAL: Rituximab|DRUG: Dacarbazine|DRUG: Doxorubicin|DRUG: Vinblastine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Nasonex in the Relief of Nasal Congestion in Patients With Seasonal Allergic Rhinitis (Study P05529)
Status: COMPLETED
Conditions: Allergic Rhinitis
Interventions: DRUG: Mometasone furoate nasal spray (MFNS)|DRUG: Matching placebo nasal spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Controlled Hypotension During Functional Endoscopic Sinus Surgery
Status: COMPLETED
Conditions: Hemorrhage
Interventions: DRUG: Magnesium Sulfate|DRUG: Dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: SNAP: Measurement of the Subjective Perception of the Symptom in Hereditary Spastic Paraparesis (HSP)
Status: COMPLETED
Conditions: Hereditary Spastic Paraparesis
Interventions: OTHER: SNAP questionnaire
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study to Compare Active Tymbion Iontophoresis to Sham Tymbion Iontophoresis for Anesthesia of the Tympanic Membrane
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: Tymbion Lidocaine/epinephrine solution|COMBINATION_PRODUCT: Device: Iontophoresis System (IPS) with Drug: Tymbion lidocaine/epinephrine solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Pharmacotherapy & CM for Opioid and Cocaine Dependence
Status: COMPLETED
Conditions: Cocaine Dependence
Interventions: DRUG: Modafinil|DRUG: Sugar Pill|BEHAVIORAL: Contingency Management|DRUG: Methadone|BEHAVIORAL: cognitive behavioral treatment|BEHAVIORAL: Voucher Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of DR-2001 for the Management of Endometriosis-Related Pelvic Pain
Status: COMPLETED
Conditions: Endometriosis
Interventions: DRUG: DR-2001a|DRUG: DR-2001b|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Impact Nutritional Program During Autologous Stem Cell Transplant
Status: TERMINATED
Conditions: Hodgkin's Lymphoma|Multiple Myeloma|Non-Hodgkin's Lymphoma
Interventions: DIETARY_SUPPLEMENT: Nestle Impact Advanced Recovery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I Study of Adoptive Immunotherapy With Enriched and Expanded Autologous Natural Killer (NK) Cells for Patients With Ph+ Acute Lymphoblastic Leukemia (ALL)
Status: COMPLETED
Conditions: Acute Lymphoblastic Leukemia|Complete Hematologic Remission (CHR)|Persistent/Recurrent Minimal Residual Disease (MRD)
Interventions: OTHER: Autologous NK cells infusions
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multiple Dose Escalation Study of M201-A in Healthy Japanese Subjects
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: M201-A Injection|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: AcQMap Objectively Visualize the Etiology of Recurrent AF Following a Failed AF Ablation
Status: COMPLETED
Conditions: Recurrent Atrial Fibrillation
Interventions: DEVICE: AcQMap Imaging and Mapping System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study Assessing Cognition in Relapsing Remitting Multiple Sclerosis (RRMS) Patients Treated With BG00012
Status: COMPLETED
Conditions: Multiple Sclerosis, Relapsing-Remitting
Interventions: DRUG: dimethyl fumarate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Tolerability and Efficacy of CWT-f-002 Lubricant Eye Drops
Status: COMPLETED
Conditions: Dry Eye Disease
Interventions: DRUG: glycerin 0.7%/PEG 400 0.3%|DRUG: polyethylene glycol 400 0.4%/propylene glycol 0.3%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cyclooxygenase-2 Expression in Tissue Samples From Patients With a Normal Cervix, Cervical Intraepithelial Neoplasia, or Early Invasive Cervical Cancer
Status: WITHDRAWN
Conditions: Cervical Cancer|Precancerous Condition
Interventions: OTHER: immunohistochemistry staining method|OTHER: laboratory biomarker analysis|OTHER: medical chart review
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Localized Injection of Lidocaine and Glucocorticoid for Headache Treatment
Status: NOT_YET_RECRUITING
Conditions: Refractory Migraine
Interventions: DRUG: Lidocaine hydrochloride|DRUG: Methylprednisolone sodium succinate|OTHER: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Guided Imagery Tobacco Cessation Intervention Delivered by a Quit Line and Website
Status: COMPLETED
Conditions: Tobacco Use|Smoking Cessation|Smoking, Tobacco|Tobacco Smoking|Guided Imagery
Interventions: BEHAVIORAL: Imagery Intervention|BEHAVIORAL: Control Condition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Single Fraction Stereotactic Radiosurgery Compared With Fractionated Stereotactic Radiosurgery in Treating Patients With Resected Metastatic Brain Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Malignant Neoplasm in the Brain
Interventions: RADIATION: Single Fraction Stereotactic Radiosurgery|RADIATION: Fractionated Stereotactic Radiosurgery|PROCEDURE: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multicentre Investigation of 2 Cycles Rituximab Compared With Standard Regimen in Management of Steroid-Resistant/Relapsed Immune Thrombocytopenia （ITP）
Status: WITHDRAWN
Conditions: Immune Thrombocytopenia
Interventions: DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial Evaluating Nilotinib as Treatment for Newly Diagnosed CML Patients in Accelerated Phase.
Status: WITHDRAWN
Conditions: Chronic Myeloid Leukemia (CML)
Interventions: DRUG: AMN107
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sacroiliac Joint Injection: Comparison of Xray Versus Ultrasound
Status: COMPLETED
Conditions: Sacroiliac Joint Arthritis Causing Low Back Pain
Interventions: PROCEDURE: Sacroiliac Joint Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Drug-coated Balloon Versus Drug-eluting Stent in the Treatment of Coronary Artery Lesions in STEMI Patients in De Novo Coronary Lesions
Status: UNKNOWN
Conditions: Acute Myocardial Infarction
Interventions: DEVICE: Drug-coated balloon|DEVICE: Drug-eluting stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Observational Study of Infliximab in Participants Suffering From Ankylosing Spondylitis With Hip Involvement
Status: TERMINATED
Conditions: Spondylitis, Ankylosing
Interventions: DRUG: Infliximab|DRUG: NSAIDs|DRUG: DMARDs
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: LINQ for impEdance meAsuremeNt While Off From HF Medication Study
Status: UNKNOWN
Conditions: Heart Failure
Interventions: DRUG: Diuretic Suspension (DS)|DRUG: Diuretic Increase (DI)|DRUG: Diuretic and Medication Suspension (DMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Phase 1b Open-Label Study Investigating the Safety and Pharmacokinetics of Administration of Subcutaneous Blinatumomab for the Treatment of Relapsed/Refractory Indolent Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Non-Hodgkin's Lymphoma
Interventions: DRUG: blinatumomab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pegylated Interferon α in Previously Interferon-treated CHB（Leading Study）
Status: RECRUITING
Conditions: Chronic Hepatitis b
Interventions: DRUG: Peginterferon α-2b based treatment group|DRUG: NAs monotherapy group
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trunk Muscles and Lumbar Intervertebral Disc Degeneration in Combat Sports
Status: COMPLETED
Conditions: Other Intervertebral Disc Degeneration, Lumbar Region
Interventions: DEVICE: Lumbar disc degeneration; LDD
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Etodolac-lidocaine Patch in Subjects Experiencing Acute Delayed Onset Muscle Soreness
Status: COMPLETED
Conditions: Acute Delayed Onset Muscle Soreness (DOMS)
Interventions: DRUG: Etodolac-lidocaine topical patch|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intensified 1st Cycle Rituximab Plus 8th Cycles of R-CHOP Chemotherapy in Patients With Advanced or Bulky CD20+ Diffuse Large B-cell Lymphoma (DLBCL)
Status: COMPLETED
Conditions: Diffuse Large B-cell Lymphoma (DLBCL)
Interventions: DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment Decision Making in Early-Stage Prostate Cancer
Status: COMPLETED
Conditions: Localized Prostate Cancer
Interventions: BEHAVIORAL: CD-ROM-based prostate cancer treatment education|BEHAVIORAL: CD-ROM-based prostate ca treatment education+decision tools
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating Clinical Effects of a Spray-Type Bio-absorbable Adhesion Barrier System in Paediatric Patients
Status: COMPLETED
Conditions: Surgical Adhesions
Interventions: DEVICE: Adspray|PROCEDURE: Placebo-control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Clinical & Pathological Studies of Upper Gastrointestinal Carcinoma
Status: RECRUITING
Conditions: Stomach Cancer|Gastro-Esophageal(GE) Junction Cancer|Gastric (Stomach) Cancer|Esophageal Cancer|Gastrointestinal Stromal Tumor (GIST)
Interventions: PROCEDURE: Blood draw|PROCEDURE: Tissue tumor biopsy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Autonomic Nervous System Reactivity of the Newborn After a Nociceptive Stress: Interest of Sucrose and Non-nutritive Sucking
Status: COMPLETED
Conditions: Newborn|Neonatal Screening
Interventions: DRUG: Glucose sucking|DRUG: Water sucking|OTHER: No sucking
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: "First-in-human" Study To Assess the Safety and Tolerability of PBF-680 in Male Healthy Volunteers
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: PBF-680|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study Between Tasimelteon Capsule Formulation and Liquid Suspension Formulation in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Tasimelteon Oral Capsule|DRUG: Tasimelteon Oral Suspension
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: APPLE: Aspirin to Prevent Pregnancy Loss and Preeclampsia
Status: RECRUITING
Conditions: Pre-Eclampsia|Pregnancy Loss
Interventions: DRUG: Aspirin 162 mg|DRUG: Aspirin 81mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison Between 25 µg Vaginal Misoprostol vs Slow Release Pessary PGE2
Status: COMPLETED
Conditions: Delivery Uterine
Interventions: DRUG: Misoprostol|DRUG: Dinoprostone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Continuous Glucose Monitoring in Dialysis Patients to Overcome Dysglycemia Trial
Status: RECRUITING
Conditions: Hemodialysis|Diabete Mellitus|Continuous Glucose Monitoring
Interventions: DEVICE: Continuous glucose monitoring (CGM)|DEVICE: Usual care (Self-monitored blood glucose)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Colchicine for Patients With Chagas´ Disease( B1 Stage)
Status: UNKNOWN
Conditions: Chagas Disease|Colchicine Resistance
Interventions: DRUG: Colchicine 0.5 MG twice day for one year|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Endostar Combined With Concurrent Chemoradiotherapy For Locally Advanced Cervical Carcinoma
Status: UNKNOWN
Conditions: Cervical Carcinoma
Interventions: DRUG: Endostar|DRUG: DDP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An Efficacy and Safety Study of JNJ-64041757, a Live Attenuated Listeria Monocytogenes Immunotherapy, in Combination With Nivolumab Versus Nivolumab Monotherapy in Participants With Advanced Adenocarcinoma of the Lung
Status: TERMINATED
Conditions: Adenocarcinoma of Lung
Interventions: BIOLOGICAL: JNJ-64041757|DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Itacitinib and Tocilizumab for Steroid Refractory Acute Graft Versus Host Disease
Status: TERMINATED
Conditions: Steroid Refractory GVHD|Graft Vs Host Disease
Interventions: DRUG: Itacitinib|DRUG: Tocilizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: NexGen EBA Radiologic and Immunologic Biomarkers of Sterilizing Drug Activity in Tuberculosis
Status: COMPLETED
Conditions: Pulmonary Tuberculosis
Interventions: DRUG: Treatment|RADIATION: PET/CT Scan|PROCEDURE: Sample Collection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Arthroscopic Rotator Cuff Repair Utilizing Mechanical Bone Debridement Versus Coblation Debridement
Status: RECRUITING
Conditions: Rotator Cuff Tears
Interventions: PROCEDURE: Coblation Debridement (FLOW90)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Monotherapy Study of MP-513 in Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Teneligliptin 20 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Risperidone-Induced Hyperprolactinemia Treated With Bromocriptine
Status: UNKNOWN
Conditions: Schizophrenia|Hyperprolactinemia
Interventions: DRUG: Bromocriptin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Imatinib + MTC in Relapsed / Refractory Acute Myeloid Leukemia (AML)
Status: COMPLETED
Conditions: AML
Interventions: DRUG: Glivec|DRUG: Mitoxantrone|DRUG: Topotecan|DRUG: AraC
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open-label Study of Epratuzumab in Serologically-positive Systemic Lupus Erythematosus Patients With Active Disease
Status: COMPLETED
Conditions: Systemic Lupus Erythematosus
Interventions: BIOLOGICAL: Epratuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Methylenetetrahydrofolate Reductase Deficiency in Ischemic Stroke
Status: COMPLETED
Conditions: Hyperhomocysteinemia, Thrombotic, Cbs-Related|Ischemic Stroke|Epilepsy
Interventions: GENETIC: Methylenetetrahydrofolate reductase (MTHFR) deficiency
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Role of Lung Ultrasonography in Detecting Extravascular Lung Water in Major Oncosurgeries
Status: COMPLETED
Conditions: Extravascular Lung Water
Interventions: DIAGNOSTIC_TEST: PVI Guided fluid management during surgery for (PVI<12) colloid bolus will be given .|DIAGNOSTIC_TEST: CVP Guided Fluid management during surgery for CVP<10 cms H2O colloid bolus will be given
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy and Safety of CAR-T Cells Therapy for Chronic or Refractory Primary Immune Thrombocytopenia (ITP)
Status: RECRUITING
Conditions: ITP - Immune Thrombocytopenia
Interventions: BIOLOGICAL: CAR-T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ATH-1017 Treatment in Subjects With Parkinson's Disease Dementia or Dementia With Lewy Bodies (SHAPE Trial)
Status: COMPLETED
Conditions: Parkinson Disease Dementia|Dementia With Lewy Bodies
Interventions: DRUG: ATH-1017|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of the Extract of the Flour Fermented With Bacillus Subtilis Var Natto DC-15 on Postprandial Glucose
Status: COMPLETED
Conditions: Prediabetes
Interventions: DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: Bacillus subtilis var natto DC-15
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Baduanjin Exercise for Patients With Chronic Heart Failure on Phase II Cardiac Rehabilitation
Status: UNKNOWN
Conditions: Rehabilitation With CHF; NYHA Class I or II
Interventions: BEHAVIORAL: Baduanjin exercise|BEHAVIORAL: Routine rehabilitation group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Dry Needling Adjuvant to Selective Serotonin Reputake Inhibitors vs TP Injection for Pain Management
Status: ACTIVE_NOT_RECRUITING
Conditions: Pain|Fibromyalgia
Interventions: OTHER: Dry Needling|PROCEDURE: Trigger points injections|DRUG: serotonin reuptake inhibitor (SSRI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: AML/MDS Drug Sensitization by in Vivo Chemotherapy Administration
Status: RECRUITING
Conditions: Acute Myeloid Leukemia|Myelodysplastic Syndromes
Interventions: PROCEDURE: Peripheral blood draw|PROCEDURE: Bone marrow aspirate|PROCEDURE: Buccal swab
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Stenting With or Without Coating Compared With Angioplasty in Non-benestent Disease
Status: UNKNOWN
Conditions: Coronary Artery Disease
Interventions: DEVICE: Bx Sonic & Cypher stent from Cordis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BBTI vs PSR in Musculoskeletal Orofacial Pain Adults
Status: COMPLETED
Conditions: Myofascial Pain|Myalgia
Interventions: BEHAVIORAL: Brief Behavioral Therapy for Insomnia, BBTI|BEHAVIORAL: Physical Self-Regulation, PSR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Combined Gum-chewing and Parenteral Metoclopramide on Post-operative Ileus
Status: COMPLETED
Conditions: Ileus Postoperative
Interventions: DRUG: Metoclopramide 10mg|COMBINATION_PRODUCT: Gum and metoclopramide|OTHER: Gum|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Intra-Arterial Oxaliplatin Plus Capecitabine to Treat Liver Metastases From Colorectal Cancer
Status: UNKNOWN
Conditions: Liver Metastasis Colon Cancer
Interventions: COMBINATION_PRODUCT: Intra-arterial LIOX + Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High Frequency Chest Wall Oscillations Versus Lung Flute in Chronic Obstructive Pulmonary Disease Post(SARS-CoV-2)
Status: UNKNOWN
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DEVICE: high frequency chest wall oscillation with vest system|DEVICE: Lung flute (OPEP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Combination Therapy With Venetoclax, Daratumumab and Dexamethasone (With and Without Bortezomib) in Participants With Relapsed or Refractory Multiple Myeloma
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: Dexamethasone|DRUG: Daratumumab|DRUG: Venetoclax|DRUG: Bortezomib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Radial Extracorporeal Shockwave Therapy on Ultrasonography Changes in Patients With Iliotibial Band Syndrome
Status: NOT_YET_RECRUITING
Conditions: Iliotibial Band Syndrome
Interventions: OTHER: Radial Extracorporeal Shockwave|OTHER: traditional therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Liraglutide Effects on Epicardial Fat Inflammatory Genes
Status: RECRUITING
Conditions: Type2 Diabetes|Coronary Artery Disease
Interventions: DRUG: Liraglutide Pen Injector [Victoza]|DRUG: matching liraglutide-placebo pre-filled pens
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study, Evaluating Pharmacokinetics, Immunogenicity and Safety Profiles of Pertuzumab Compared to Perjeta® in Healthy Man
Status: ACTIVE_NOT_RECRUITING
Conditions: Healthy Men
Interventions: DRUG: Pertuzumab|DRUG: Perjeta®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: SOLVE-ACS: Bioresorbable Magnesium-Stents Magmaris in ACS Lesions
Status: TERMINATED
Conditions: Acute Coronary Syndrome|STEMI - ST Elevation Myocardial Infarction|NSTEMI - Non-ST Segment Elevation MI
Interventions: DEVICE: Implantation of the Magmaris scaffold
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Laparocopic Sleeve Gastrectomy With or Without Liraglutide in Obese Patients
Status: COMPLETED
Conditions: Weight Loss
Interventions: DRUG: Liraglutide 6 MG/ML|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial of Tadalafil in Interstitial Lung Disease of Scleroderma
Status: COMPLETED
Conditions: Lung Diseases, Interstitial
Interventions: DRUG: Tadalafil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of 17β-estradiol on Skeletal Muscle
Status: WITHDRAWN
Conditions: Muscle Atrophy
Interventions: DRUG: 17β-estradiol|DRUG: Polycose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Combination Chemotherapy, Peripheral Stem Cell Transplantation, and Radiation Therapy in Treating Patients With Ewing's Sarcoma, Peripheral Primitive Neuroectodermal Tumor, or Rhabdomyosarcoma
Status: COMPLETED
Conditions: Sarcoma
Interventions: BIOLOGICAL: filgrastim|DRUG: busulfan|DRUG: melphalan|DRUG: thiotepa|PROCEDURE: peripheral blood stem cell transplantation|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Development of Problem-solving Skills Among Female Adolescents by Application of Social Cognitive Theory in Parent-Child Relationship
Status: UNKNOWN
Conditions: Adolescent Girls
Interventions: OTHER: educational program for Development of problem-solving skills|OTHER: no education program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: 177Lu-PSMA as a Systemic Adjuvant Treatment in Patients With High and Very High Risk Prostate Cancer
Status: NOT_YET_RECRUITING
Conditions: Prostate Cancer
Interventions: DRUG: Lutetium (177Lu) vipivotide tetraxetan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Perfluorocarbon (PFC) Inhalation Treatment of Acute Lung Injury/Acute Respiratory Distress Syndrome
Status: UNKNOWN
Conditions: Respiratory Distress Syndrome, Adult|Acute Lung Injury
Interventions: DRUG: Perfluorocarbon|DRUG: Sterile Water for Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: AZD9291 (Osimertinib) Versus Platinum-Based Doublet-Chemotherapy in Locally Advanced or Metastatic Non-Small Cell Lung Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Anticancer Treatment
Interventions: DRUG: Chemotherapy|DRUG: Cross-over to Osimertinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Standardization of Urine Collection Using PEEZY Device as Compared to Clean Peezy for DAB
Status: UNKNOWN
Conditions: Asymptomatic Bacteriuria|Urinary Tract Infections
Interventions: DEVICE: Peezy urine collection device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT