pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: ARB and CCB Longest Combination Treatment on Ambulatory and Home BP in Hypertension With Atrial Fibrillation -Multicenter Study on Time of Dosing (ACROBAT)
Status: UNKNOWN
Conditions: Hypertension and Atrial Fibrillation
Interventions: DRUG: Telmisartan-amlodipine tablet administration group (morning)|DRUG: Telmisartan-amlodipine tablet administration group (bedtime)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ESPB vs.Combination of ESPB and Superficial PIPB in Cardiac Surgery
Status: COMPLETED
Conditions: Anesthesia|Analgesia|Acute Pain|Patient Controlled Analgesia
Interventions: PROCEDURE: Bilateral ultrasound-guided ESPB|PROCEDURE: Bilateral ultrasound-guided ESPB and superficial PIPB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Pilot Study of Dextromethorphan for the Prevention and Treatment of Methotrexate Neurotoxicity
Status: TERMINATED
Conditions: Neurotoxicity Syndromes
Interventions: DRUG: Dextromethorphan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Interest of Qutenza in Patients With Head and Neck Cancer in Remission and With Sequelae Neuropathic Pain.
Status: RECRUITING
Conditions: Head and Neck Cancer
Interventions: DRUG: Capsaïcin patch (Qutenza®)|DRUG: Amitriptyline (Laroxyl®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radiolabeled Glass Beads Used for Treating Patients With Primary Liver Cancer When Surgery is Not an Option
Status: COMPLETED
Conditions: Liver Cancer|Hepatoma
Interventions: DEVICE: Yttrium 90 (TheraSphere)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of ABT-089 on Smoking Abstinence Symptoms and Reward
Status: TERMINATED
Conditions: Nicotine Addiction
Interventions: DRUG: ABT-089|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Denosumab Fracture Intervention Randomized Placebo Controlled Trial in Japanese Patients With Osteoporosis
Status: COMPLETED
Conditions: Osteoporosis
Interventions: DRUG: Denosumab|DRUG: Placebo|DRUG: Alendronate sodium hydrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Safety and Pharmacokinetics Study of UCB7853 in Healthy Study Participants and Study Participants With Parkinson's Disease (PD)
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DRUG: UCB7853|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect of Hot Cataplasm With Caraway Oil in the Treatment of Irritable Bowel Syndrome
Status: COMPLETED
Conditions: Irritable Bowel Syndrome
Interventions: DRUG: caraway oil|DRUG: Olive oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Longitudinal Follow-up of High Viscosity Glassionomer IonoStar Plus Versus a Composite Bulk X-tra-Fil Combined With Futurabond U (Splith Mouth Study): Reunion Island, Circus of Mafate
Status: TERMINATED
Conditions: Caries
Interventions: OTHER: Caries treatment|OTHER: Caries treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Coronary Angiography Before Elective Carotid Endarterectomy in Patients With Asymptomatic Coronary Artery Disease
Status: COMPLETED
Conditions: Carotid Stenosis|Coronary Stenosis
Interventions: OTHER: Preoperative coronary angiography|OTHER: Standard cardiac workup
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dasatinib in Treating Patients With Previously Treated Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Recurrent Colon Cancer|Recurrent Rectal Cancer|Stage IV Colon Cancer|Stage IV Rectal Cancer
Interventions: DRUG: dasatinib|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigating the Impact of Acupuncture on the Quality of Life of Primitive Headaches Patients
Status: RECRUITING
Conditions: Headache Migraine
Interventions: OTHER: Real acupuncture|OTHER: Sham acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Nasal High-flow Versus Venturi Mask Oxygen Therapy in the Post-extubation Period
Status: COMPLETED
Conditions: Respiratory Failure
Interventions: DEVICE: Venturi mask|DEVICE: Nasal high-flow
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phase 2 Trial of Carfilzomib for Metastatic Castration-resistant Prostate Cancer Following Treatment
Status: COMPLETED
Conditions: Metastatic Castration-resistant Prostate Cancer
Interventions: DRUG: Carfilzomib|DRUG: Dexamethasone|DRUG: Acyclovir
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessing Changes in Multi-parametric MRI in MS Patients Taking Clemastine Fumarate as a Myelin Repair Therapy
Status: RECRUITING
Conditions: Multiple Sclerosis (MS)|Multiple Sclerosis, Relapsing-Remitting|Multiple Sclerosis, Primary Progressive|Multiple Sclerosis, Chronic Progressive|Multiple Sclerosis Relapse|Multiple Sclerosis Brain Lesion|Multiple Sclerosis Benign
Interventions: DRUG: Clemastine Fumarate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Implementation of Physical Cancer Rehabilitation Programmes in a European Healthcare System.
Status: UNKNOWN
Conditions: Cancer|Fatigue
Interventions: OTHER: The patient-directed (PD) strategy|OTHER: The multi-faceted (MF) strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: |Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Impact of Different Modes of Ventilation With Laryngeal Mask Airway on Pediatric Cataract Surgery
Status: COMPLETED
Conditions: Ventilation|Laryngeal Mask Airway|Cataract Surgery
Interventions: PROCEDURE: Pressure Support Ventilation|PROCEDURE: Unparalyzed Pressure Control Ventilation|PROCEDURE: Paralyzed Pressure Control Ventilation|DEVICE: Laryngeal Mask Airway|DRUG: Sevoflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Community Health Advocates for Motivating PAP Use in Our Neighborhoods.
Status: RECRUITING
Conditions: Obstructive Sleep Apnea
Interventions: BEHAVIORAL: Motivational Enhancement Therapy|DEVICE: Positive Airway Pressure (PAP) therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: FOLFOXIRI + Bev + Atezo vs FOLFOXIRI + Bev as First-line Treatment of Unresectable Metastatic Colorectal Cancer Patients
Status: COMPLETED
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: Bevacizumab|DRUG: Irinotecan|DRUG: Oxaliplatin|DRUG: L-Leucovorin|DRUG: 5-fluorouracil|DRUG: Atezolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Combined Effects of Resistance Training and Flax Oil Supplementation Upon Inflammation in Older Adults
Status: COMPLETED
Conditions: Inflammation|Sarcopenia
Interventions: DIETARY_SUPPLEMENT: flax oil containing alpha linolenic acid|BEHAVIORAL: Resistance exercise training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Exercise With AR Glasses on Metabolic Parameters and Anthropometric Measurements in Obese Adolescents
Status: RECRUITING
Conditions: Childhood Obesity
Interventions: OTHER: Exercise with augmented reality glasses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Boosting Resources for Tracheostomy Care at Home
Status: ENROLLING_BY_INVITATION
Conditions: Tracheostomy|Caregiver Burden
Interventions: BEHAVIORAL: Trach Plus|BEHAVIORAL: Trach Me Home
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Detection of Amyloid Deposits in the Wrist by MRI With Mapping and High Resolution Sequences in Systemic Amyloidosis (AMYLOCARP)
Status: UNKNOWN
Conditions: Amyloid|Systemic Amyloidosis
Interventions: PROCEDURE: MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Proof-of-concept Study of Ibrutinib in c-MYC and HER2 Amplified Oesophagogastric Carcinoma
Status: UNKNOWN
Conditions: Gastrooesophageal Cancer
Interventions: DRUG: ibrutinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diagnostic Accuracy of Capsule Endoscopy in Small Bowel Crohn's Disease
Status: COMPLETED
Conditions: Crohn's Disease
Interventions: DEVICE: Capsule endoscopy, CT enterography, colonoscopy, small bowel follow-through
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Changes of Macular Pigment and Parameters of Eyes After YAG Laser Treatment in Cases With Capsule Opacification
Status: COMPLETED
Conditions: Posterior Capsule Opacification|Retinal Degeneration|Retinal Detachment|Anterior Chamber Angle Congestion|Macula Edema|Macular Pigmentation|Choroid Disease
Interventions: DEVICE: Nd: YAG laser posterior capsulotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Recombinant Human Serum Albumin/Interferon alpha2b Fusion Protein in Chinese Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: BIOLOGICAL: Human Serum Albumin/interferon alpha2b|BIOLOGICAL: Peginterferon 180 μg single dose S.C.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: E-health and People Living With Major Neurocognitive Disorder - CARE© and ESOGER© Applications
Status: RECRUITING
Conditions: Major Neurocognitive Disorder|Frailty
Interventions: OTHER: Recommendations and reorientation towards healthcare resources
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Multi-virus CTLs Expressing CD19 Chimeric Receptors, CD19 Positive Malignancies Post SCT, MULTIPRAT
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Lymphoblastic Leukemia (ALL)|Chronic Lymphocytic Leukemia (CLL)|Non Hodgkin's Lymphoma
Interventions: GENETIC: CD19CAR/virus specific T cells|DRUG: Benadryl and Tylenol
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevention of Colorectal Cancer Through Multiomics Blood Testing
Status: ACTIVE_NOT_RECRUITING
Conditions: Colon Cancer|Rectal Cancer|Colon Neoplasm|Colon Diseases|Colon Lesion|Colon Polyp|Colorectal Cancer|Polyp|Adenoma|Rectal Diseases|Gastrointestinal Tract Cancers
Interventions: DIAGNOSTIC_TEST: Freenome test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Efficacy Study of the Sorin 3D Annuloplasty Ring For Mitral Repair
Status: COMPLETED
Conditions: Mitral Valve Regurgitation
Interventions: DEVICE: Implantation of the MEMO 3D Annuloplasty Ring
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neurorestorative Effects of Electroconvulsive Therapy (ECT) in Patients With Severe Late Life Depression
Status: COMPLETED
Conditions: Depression
Interventions: PROCEDURE: ECT|DRUG: Etomidate|DRUG: Succinylcholine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Impact of a Mailed Educational Reminder on Fecal Occult Blood Testing (FOBT): A Randomized Controlled Trial
Status: COMPLETED
Conditions: Colon Cancer
Interventions: OTHER: Mailed Educational Reminder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: A Study of CNP520 Versus Placebo in Participants at Risk for the Onset of Clinical Symptoms of Alzheimer's Disease
Status: TERMINATED
Conditions: Alzheimers Disease
Interventions: DRUG: CNP520 50mg|DRUG: CNP520 15mg|OTHER: Matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Treatment Adherence With an Integrated Program on HbA1c Scores in Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: BEHAVIORAL: ASMART|OTHER: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Extension Study of the Safety and Efficacy of Armodafinil in the Treatment of Patients With Excessive Sleepiness
Status: COMPLETED
Conditions: Excessive Daytime Sleepiness|Narcolepsy|Obstructive Sleep Apnea/Hypopnea Syndrome|Chronic Shift Work Sleep Disorder
Interventions: DRUG: Armodafinil 100 to 250 mg/day
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Peri-OPerative COlchicine to Reduce Negative Events (POPCORN) Trial
Status: RECRUITING
Conditions: Coronary Artery Disease
Interventions: DRUG: Colchicine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacogenetic Testing of Patients With Unwanted Adverse Drug Reactions or Therapy Failure
Status: RECRUITING
Conditions: Adverse Drug Reaction|Therapy Failure
Interventions: DIAGNOSTIC_TEST: Buccal swab|DIAGNOSTIC_TEST: EDTA Blood sample (4.9mL)|DIAGNOSTIC_TEST: Serum sample (7.5mL)|OTHER: communication of test results|OTHER: unstructured interview
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Sleep-maintenance Activity of 3 Doses of SKP-1041
Status: COMPLETED
Conditions: Sleep Disorder|Primary Insomnia
Interventions: DRUG: placebo|DRUG: SKP-1041 (experimental formulation of zaleplon)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Development of Clinical Method to Determination Triclosan Retention in Plaque Following Brushing.
Status: COMPLETED
Conditions: Gingival Diseases
Interventions: DRUG: Fluoride|DRUG: Triclosan/Fluoride toothpaste|DRUG: Fluoride|DRUG: Fluoride|OTHER: antibacterial plant extract
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Application and Effectiveness of the STEPPS in Patients With BPD, Extending to Their Families With the FC Program
Status: RECRUITING
Conditions: Borderline Personality Disorder (BPD)
Interventions: BEHAVIORAL: STEPPS plus Family Connections|BEHAVIORAL: STEPPS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study to Learn About How Different Amounts of the Study Medicine PF-07826390 Act in the Body of People With Cancer When Taken Alone or With Other Anti-cancer Medicines.
Status: NOT_YET_RECRUITING
Conditions: Neoplasms|Non-small-cell Lung Cancer|Squamous Cell Carcinoma of the Head and Neck|Renal Cell Carcinoma|Colorectal Carcinoma|Ovarian Carcinoma
Interventions: DRUG: PF-07826390|BIOLOGICAL: sasanlimab|OTHER: SOC (anti-PD-1 + platinum -based chemo)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Contralateral Study of WaveLight® Femtosecond Laser Devices for Corneal Flap Creation
Status: RECRUITING
Conditions: Refractive Errors
Interventions: DEVICE: UV fs-Laser|DEVICE: IR fs-Laser|PROCEDURE: LASIK
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Hydroxychloroquine, Telmisartan and Azithromycin on the Survival of Hospitalized Elderly Patients With COVID-19
Status: TERMINATED
Conditions: COVID-19 Infection
Interventions: DRUG: Hydroxychloroquine|DRUG: Azithromycin|DRUG: Telmisartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Alfacalcidol Supplementation on Levator Ani Muscle Strength of Menopausal Pelvic Organ Prolapse Patients
Status: COMPLETED
Conditions: Pelvic Organ Prolapse
Interventions: DRUG: Alfacalcidol 0.0005 MG|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial of PRAX-562 in Subjects With Developmental and Epileptic Encephalopathies (DEE)
Status: RECRUITING
Conditions: SCN2A Encephalopathy|SCN8A Encephalopathy
Interventions: DRUG: Part A: 0.5mg/kg/day PRAX-562 for 16 Weeks|DRUG: Part A: 0.5mg/kg/day PRAX-562 for 12 Weeks and Matching Placebo for 4 Weeks|DRUG: Part B: 0.5mg/kg/day PRAX-562
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Plavix on NO (Nitrogen Monoxide) Production of the Endothelial Function
Status: COMPLETED
Conditions: Peripheral Arterial Disease
Interventions: DRUG: Clopidogrel (Plavix)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Neuro 1 and Neuro 2 Cochlear Implant Speech Processors
Status: COMPLETED
Conditions: Sensorineural Hearing Loss|Cochlear Hearing Loss
Interventions: OTHER: Satisfaction questionnaire|BEHAVIORAL: Speech intelligibility in quiet|BEHAVIORAL: Speech intelligibility in noise|BEHAVIORAL: VRB (Vocale Rapide dans le Bruit)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Caelyx as Primary Treatment for Patients With Breast Cancer and a History of Heart Disease and/or Age Over 65 Years
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Liposomal pegylated doxorubicine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CBART: The Reduction of Psychological and Physiological Stress in Women Undergoing IVF
Status: COMPLETED
Conditions: Psychological Stress|DNA Degradation, Apoptotic|Telomere Shortening|Fertility Disorders
Interventions: BEHAVIORAL: CBART
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Respiratory Outcome at Adolescence of Very Low Birthweight Infants
Status: COMPLETED
Conditions: Premature Baby 26 to 32 Weeks|Bronchopulmonary Dysplasia
Interventions: OTHER: Prevention and follow-up of the patients pulmonary parameters
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effectiveness and Security Testing of a Mobile App (B·RIGHT) for Emotional Crisis in Borderline Personality Disorder
Status: UNKNOWN
Conditions: Borderline Personality Disorder
Interventions: BEHAVIORAL: Treatment as usual (schema therapy)|DEVICE: Mobile app
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Hypertonic Sodium Lactate Solution Compared With 6% HES Solution in CABG Patients
Status: COMPLETED
Conditions: Coronary Heart Disease
Interventions: DRUG: Hypertonic sodium lactate|DRUG: 6% Hydroxy Ethyl Starch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Changes of Endotracheal Tube Cuff Pressures After Ear, Head and Neck Surgery Positions
Status: COMPLETED
Conditions: Endotracheal Tube Cuff Pressure|Surgery; Ear|Surgery; Head and Neck|Position
Interventions: OTHER: Intracuff pressure measurement|OTHER: Intracuff pressure measurement|OTHER: Intracuff pressure measurement
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: the Invasive and Conservative Strategies in Elderly Frail Patients With Non-STEMI
Status: COMPLETED
Conditions: Non-ST Elevation Myocardial Infarction|Frail Elderly Syndrome
Interventions: PROCEDURE: Invasive|PROCEDURE: Conservative
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The CYBERnetic LowEr Imb coGnitive Ortho-prostheis Plus Plus, 2nd Clinical Study (CLs++)
Status: UNKNOWN
Conditions: Lower Limb Amputation Above Knee (Injury)
Interventions: DEVICE: Cyberlegs Xleg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gilotrif (Afatinib) in Advanced Non-Small Cell Lung Cancer Patients Pre-treated With Erlotinib or Gefitinib
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: Gilotrif
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Drug Therapy Induced Weight Loss to Improve Blood Vessel Function in Subjects With Obesity
Status: TERMINATED
Conditions: Obesity|Metabolic Syndrome X
Interventions: DRUG: Metformin|DRUG: Orlistat|DRUG: Topiramate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treating Nightmares in Posttraumatic Stress Disorder With Clonidine and Doxazosin
Status: RECRUITING
Conditions: Posttraumatic Stress Disorder
Interventions: DRUG: Clonidine|DRUG: Doxazosin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: TOLER-ENT Study: A Study to Investigate the Tolerance of the High Energy, High Protein Formula Sondalis® HP 2 kcal
Status: RECRUITING
Conditions: Malnutrition
Interventions: DIETARY_SUPPLEMENT: Sondalis® HP 2 kcal (with or without fibre)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: MDMA-assisted Prolonged Exposure Therapy for Comorbid Alcohol Use Disorder and Post-traumatic Stress Disorder
Status: RECRUITING
Conditions: PTSD|Alcohol Use Disorder|Alcohol Dependence|Post-traumatic Stress Disorder|Comorbidities and Coexisting Conditions
Interventions: BEHAVIORAL: Prolonged exposure therapy|DRUG: MDMA|DRUG: Niacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Narcolepsy Protect Against Alzheimer's Disease?
Status: COMPLETED
Conditions: Narcolepsy|Amyloid Pathology
Interventions: DEVICE: PET-scan18F-AV-45|DEVICE: PET-scan18F-AV-45
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: fMRI-behavioral Study of Cholinergic Augmentation With Donepezil in Healthy Sleep Deprived Adults
Status: COMPLETED
Conditions: Sleep Deprivation
Interventions: DRUG: donepezil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: TRANexamic Acid to Reduce Bleeding in BURN Surgery
Status: COMPLETED
Conditions: Tranexamic Acid|Burns|Surgery|Wounds and Injuries
Interventions: DRUG: Tranexamic Acid|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Erlotinib in Neoadjuvant Setting in Patients With Stage IIIA, N2-positive Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Neoplasms|Erlotinib|Neoadjuvant Therapy
Interventions: DRUG: Erlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PI3K Inhibitor BKM120 and Docetaxel in Treating Patients With Advanced Solid Tumor That is Locally Advanced, Cannot Be Removed By Surgery, or Metastatic
Status: COMPLETED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: PI3K inhibitor BKM120|DRUG: docetaxel|OTHER: pharmacological study|OTHER: questionnaire administration|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Behavioral Economics Applications to Geriatrics Leveraging EHRs R33 Trial
Status: COMPLETED
Conditions: Prostate Specific Antigen Screening|Asymptomatic Bacteriuria|Type 2 Diabetes
Interventions: BEHAVIORAL: EHR clinical decision support nudges|BEHAVIORAL: Brief clinician education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Impact of the Radiographic Examination on Diagnosis and Treatment Decision of Caries Lesions in Primary Teeth
Status: COMPLETED
Conditions: Dental Caries|Teeth Loss|Quality of Life
Interventions: PROCEDURE: Dental treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of Duloxetine (LY248686) in the Treatment of Japanese Children and Adolescents With Depressive Disorder
Status: TERMINATED
Conditions: Depressive Disorder
Interventions: DRUG: Duloxetine Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Single and Multiple Ascending Dose Study of CK-4021586 in Healthy Adult Participants
Status: RECRUITING
Conditions: Healthy Participants
Interventions: DRUG: CK-4021586|DRUG: Placebo for CK-4021586
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of the Everolimus Eluting With the Biolimus A9 Eluting Stent
Status: UNKNOWN
Conditions: Coronary Artery Disease
Interventions: DEVICE: the everolimus eluting ® stent|DEVICE: the Biolimus A9 eluting NOBORI® stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Loco-regional B7H3 IL-7Ra CAR T Cell in DIPG
Status: RECRUITING
Conditions: DIPG Brain Tumor|Diffuse Intrinsic Pontine Glioma
Interventions: BIOLOGICAL: B7H3 specific CAR T cell with IL-7Ra signaling domain
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Medical Consortium for Screening Upper Gastrointestinal Cancers With Magnetically Controlled Capsule Gastroscopy
Status: UNKNOWN
Conditions: Capsule Endoscopy|Cancer of Stomach|Cancer of Esophagus|Health Policy
Interventions: OTHER: Medical Consortium
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Study of BBIL's ROTAVAC® and ROTAVAC 5CM Vaccines in Zambia
Status: COMPLETED
Conditions: Diarrhea|Diarrhea Rotavirus
Interventions: BIOLOGICAL: ROTAVAC®|BIOLOGICAL: ROTAVAC 5D|BIOLOGICAL: Rotarix®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Immersion, Performed Under the Conditions of Obstetrical Dilatation Bath, on Diuresis and Hemodynamic Variables in Young Women
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: Lying in a bath during 2 hours|OTHER: Lying in a bed during 2 hours
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Zirconium-89-girentuximab PET/CT Imaging in Renal Cell Carcinoma
Status: COMPLETED
Conditions: Renal Cell Carcinoma
Interventions: DRUG: Zirconium-89 girentuximab PET/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Pilot Study: Acceptability, Feasibility and Efficacy of Vaginal Insemination in HIV Discordant Couples (Female Positive, Male Negative) Desiring Conception in Kisumu, Kenya
Status: COMPLETED
Conditions: HIV Discordant Couples
Interventions: PROCEDURE: Vaginal Insemination
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Investigation of Effects of Physiotherapy Interventions on Mechanical Properties of Muscle in Head and Neck Cancer
Status: RECRUITING
Conditions: Head and Neck Cancer|Spinal Accessory Nerve Injury|Thyroid Cancer|Scapular Dyskinesis|Cervical Pain|Shoulder Pain
Interventions: OTHER: Myofascial Release Technique|OTHER: Exercise|OTHER: Scar Tissue Massage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intraoperative Liposomal Bupivacaine vs. Bupivacaine for Total Hip Replacement Pain Management
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: DRUG: Liposomal Bupivacaine|DRUG: 0.25% Bupivacaine with epinephrine|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate REbamiPide as an Adjuvant Regimen to Heal erosIve Reflux Esophagitis
Status: COMPLETED
Conditions: Gastroesophageal Reflux
Interventions: DRUG: Lansoprazole|DRUG: Rebamipide|DRUG: Rebamipide-placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of a Supervised Exercise Program in Patients With Chronic Low Back Pain
Status: COMPLETED
Conditions: Low Back Pain|Muscle Atrophy|Diagnostic Imaging|Exercise Therapy
Interventions: OTHER: Targeted exercise program|OTHER: General exercise program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized, Placebo-controlled, Double Blind Study to Evaluate the Efficacy of 2LVERU®JUNIOR and 2LVERU® on the Treatment of Warts
Status: RECRUITING
Conditions: Common Wart|Flat Wart|Plantar Wart
Interventions: DRUG: 2LVERU® or 2LVERU® JUNIOR|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prebiotic Effects on Gut Microbiota, Gut Comfort and Immune Function
Status: RECRUITING
Conditions: Healthy|Gastrointestinal Diseases
Interventions: DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: HMO 1|DIETARY_SUPPLEMENT: HMO 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Phase 3 Trial in Bowel Preparation for Colonoscopy
Status: COMPLETED
Conditions: Bowel Preparation
Interventions: DRUG: CTP0301-A|DRUG: CTP0301-B|DRUG: Cool prep
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Thyroglobulin Point of Care Assay for Rapid Detection of Metastatic Differentiated Thyroid Carcinoma
Status: RECRUITING
Conditions: Differentiated Thyroid Cancer|Lymph Node Metastases
Interventions: DEVICE: Point of care assay for thyroglobulin (POC-Tg) evaluation of a suspected cervical lymph node
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Laparscopic Inguinal Hernia Repair - Does the Choice of Self-fixated Mesh Matter?
Status: ACTIVE_NOT_RECRUITING
Conditions: Inguinal Hernia|Surgery
Interventions: DEVICE: Adhesix mesh
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Assessing Ketorolac (Toradol) at Oocyte Retrieval
Status: RECRUITING
Conditions: Infertility|Infertility, Female|Oocyte Retrieval|Postoperative Pain|Embryo Transfer
Interventions: DRUG: Ketorolac (Toradol)|OTHER: Placebo (saline)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of ABX-1431 in Adult Patients With Tourette Syndrome or Chronic Motor Tic Disorder
Status: COMPLETED
Conditions: Tourette Syndrome|Motor Tic Disorder
Interventions: DRUG: ABX-1431|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Affect Recognition: Enhancing Performance of Persons With Acquired Brain Injury (ABI)
Status: COMPLETED
Conditions: Acquired Brain Injury (Including Stroke)
Interventions: BEHAVIORAL: Facial Affect Recognition Training|OTHER: Stories of Emotional Inference
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Ridinilazole Versus Vancomycin Treatment for Clostridium Difficile Infection
Status: COMPLETED
Conditions: Clostridioides Difficile Infection
Interventions: DRUG: Ridinilazole|DRUG: Vancomycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study on the Safety of Neladenoson Bialanate, How it is Tolerated and the Way the Body Absorbs, Distributes and Gets Rid of the Study Dug Given as a Single Oral Dose in Participants With Liver Impairment and Healthy Participants Matched for Age-, Gender-, and Weight
Status: TERMINATED
Conditions: Pharmacology, Clinical
Interventions: DRUG: Neladenoson bialanate (BAY 1067197)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of a Comprehensive School Health Programme in Zambia
Status: ACTIVE_NOT_RECRUITING
Conditions: Helminth Infection|Malaria|Schistosomiasis|Anemia|UTI|Diarrhea|Skin Rash|Cough
Interventions: OTHER: Comprehensive School Health Programme|OTHER: Deworming and vitamin A supplementation delivery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Spine Angle Comparison in Adult Seating Posture With Immediate Feedback
Status: COMPLETED
Conditions: Spinal Curvatures|Feedback, Psychological|Sitting Position
Interventions: DEVICE: immediately feedback device|DEVICE: Unstable chair|OTHER: Standard chair
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Effect of Magnesium Alginate on Gastroesophageal Reflux in Infants.
Status: UNKNOWN
Conditions: Gastroesophageal Reflux
Interventions: DIETARY_SUPPLEMENT: thickened formula|DIETARY_SUPPLEMENT: Mg alginate|BEHAVIORAL: reassurance with lifestyle changes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Men in Maternity Health (MiM) in Myanmar
Status: COMPLETED
Conditions: Maternal Health Care|Myanmar|Men in Maternity Health|Male Partner|Institutional Delivery
Interventions: BEHAVIORAL: Men in Maternity Health (MiM) Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Effectiveness of Core-Needle US Guided Biopsy as Primary Tool For Diagnosis of Thyroid Nodules
Status: COMPLETED
Conditions: Thyroid Nodule|Thyroid Diseases|Thyroid Gland; Node
Interventions: PROCEDURE: FNB|PROCEDURE: Core biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Development and Pilot Evaluation of a Web-supported Programme of Constraint Induced Therapy Following Stroke (LifeCIT)
Status: COMPLETED
Conditions: Stroke
Interventions: BEHAVIORAL: LifeCIT|BEHAVIORAL: Standard Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Two Type III GBS Polysaccharide-Tetanus Toxoid Conjugate Vaccines
Status: COMPLETED
Conditions: Bacterial Infections|Group B Streptococcus
Interventions: BIOLOGICAL: GBS III-TT-SSI|BIOLOGICAL: GBS III-TT-MPHL
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: A Study in Participants With Rheumatoid Arthritis on Background Methotrexate Therapy
Status: COMPLETED
Conditions: Arthritis, Rheumatoid
Interventions: DRUG: LY3009104|DRUG: Placebo|DRUG: Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Polatuzumab Vedotin in Combination With Rituximab or Obinutuzumab, Cyclophosphamide, Doxorubicin, and Prednisone in Participants With B-Cell Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Lymphoma, Non Hodgkin
Interventions: DRUG: Cyclophosphamide|DRUG: Doxorubicin|DRUG: Obinutuzumab|DRUG: Polatuzumab Vedotin|DRUG: Prednisolone|DRUG: Prednisone|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HFNC vs LFNC in Patients With AF Undergoing RFCA Under Deep Sedation.
Status: RECRUITING
Conditions: Deep Sedation|Oxygen Therapy|Radiofrequency Ablation
Interventions: DEVICE: High flow nasal cannula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TIL Therapy for Metastatic Renal Cell Carcinoma
Status: UNKNOWN
Conditions: Metastatic Renal Cell Carcinoma
Interventions: PROCEDURE: Surgical removal of tumor tissue for T cell production|DRUG: Cyclophosphamide|DRUG: Fludarabine|BIOLOGICAL: TIL infusion|DRUG: Interleukin-2
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Study of STN1012600 Ophthalmic Solution in Healthy Adult Males Volunteers
Status: COMPLETED
Conditions: Healthy Adult Males Volunteers
Interventions: DRUG: STN1012600 ophthalmic solution 0.002%
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Tai Chi Training for the Prophylaxis of Migraine in Chinese Women
Status: COMPLETED
Conditions: Migraine Disorder
Interventions: BEHAVIORAL: Tai Chi training|OTHER: Waiting list control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Abiraterone, Radiotherapy and Short-Term Androgen Deprivation in Unfavorable Localized Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: Abiraterone acetate|DRUG: Androgen deprivation|RADIATION: Radiation Therapy|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sleep Disordered Breathing With Opioid Use
Status: RECRUITING
Conditions: Sleep Apnea|Opioid Use|Sleep Disordered Breathing
Interventions: OTHER: Hyperoxia|DRUG: Acetazolamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Phase 3 Study to Evaluate the Efficacy and Safety of Intravenous BIIB093 (Glibenclamide) for Severe Cerebral Edema Following Large Hemispheric Infarction
Status: TERMINATED
Conditions: Brain Edema|Stroke, Acute
Interventions: DRUG: BIIB093|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Glycemic Response to Momordica Charantia in Type 2 Diabetes
Status: WITHDRAWN
Conditions: Type 2 Diabetes
Interventions: DRUG: Momordica charantia|OTHER: starch powder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of CDX-011 (CR011-vcMMAE) in Patients With Advanced GPNMB-expressing Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: CDX-011|DRUG: "Investigator's Choice" chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Patient-adjusted Versus Physician-adjusted Titration of BIAsp 30 Combined With Metformin in Type 2 Diabetes Patients
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: biphasic insulin aspart 30|DRUG: biphasic insulin aspart 30
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of an Intermittent Fasting and Dietary Supplement Regimen on Glycemic Variability
Status: COMPLETED
Conditions: Healthy|Impaired Glucose Tolerance
Interventions: DIETARY_SUPPLEMENT: Dietary supplement regimen|OTHER: Dietary supplement and intermittent fasting regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Post Hysterectomy Pain Prevention: Pre-op Wound Infiltration With Anesthetic Protocol Versus Standard of Care
Status: TERMINATED
Conditions: Hysterectomy
Interventions: PROCEDURE: Standard of care|PROCEDURE: Pre-emptive wound infiltration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Vascular Effects of Dietary Potassium
Status: COMPLETED
Conditions: Cardiovascular Risk Factor
Interventions: OTHER: Moderate Potassium/Low Sodium Diet|OTHER: Moderate Potassium/High Sodium Diet|OTHER: High Potassium/High Sodium Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study for Obtaining Mature Oocytes by in Vitro Maturation in Oocyte-donor Women
Status: COMPLETED
Conditions: Female Infertility
Interventions: PROCEDURE: IN VITRO MATURATION AND OOCYTE ACTIVATION
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study to Assess Adverse Events, Change in Disease Activity, and How Intravenous and Subcutaneous Risankizumab Moves Through the Body of Pediatric Participants With Moderately to Severely Active Crohn's Disease
Status: RECRUITING
Conditions: Crohn's Disease
Interventions: DRUG: Risankizumab|DRUG: Risankizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Isoniazid Dose Adjustment According to NAT2 Genotype (IDANAT2)
Status: TERMINATED
Conditions: Pulmonary Tuberculosis
Interventions: DRUG: isoniazid|DRUG: isoniazid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT