pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Evaluation of Extended Wear Infusion Set With 670G Hybrid Closed-Loop Therapy
Status: WITHDRAWN
Conditions: Type 1 Diabetes
Interventions: DEVICE: Extended Wear Infusion Set|DEVICE: Standard Infusion Set
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Analysis in the EMERGEncy Between TransVenous Cardiac PACIng Guided by Fluoroscopy Versus Echocardiogram
Status: UNKNOWN
Conditions: Bradycardia
Interventions: PROCEDURE: Transvenous cardiac pacing guided by fluoroscopy|PROCEDURE: Transvenous cardiac pacing guided by ECG/ECHO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Access Safety of Durvalumab in Indian Adult Patients With Locally Advanced NSCLC
Status: COMPLETED
Conditions: Unresectable Non-small Cell Lung Cancer (NSCLC)
Interventions: DRUG: Durvalumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Evaluation of the ProNOVA XR Polymer Free Drug Eluting Coronary Stent System
Status: COMPLETED
Conditions: Myocardial Ischemia
Interventions: DEVICE: Drug Eluting Stent implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: REDEL Trial: Reduced Elective Nodal Dose for Anal Cancer Toxicity Mitigation
Status: RECRUITING
Conditions: Anal Cancer
Interventions: RADIATION: Radiation (reduced elective nodal dose (30.6 Gy)|DRUG: Capecitabine|DRUG: Mitomycin c
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: VAgal Nerve Stimulation: safeGUARDing Heart Failure Patients
Status: COMPLETED
Conditions: Heart Failure With Reduced Ejection Fraction
Interventions: DEVICE: Equilia® Vagal Nerve Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Psychoeducational Intervention for Families With a Member Affected by Major Depression
Status: RECRUITING
Conditions: Depressive Disorder, Major
Interventions: OTHER: Psychoeducational Family Intervention|OTHER: Informative intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Sodium, Nocturnal Blood Pressure and Nocturnal Pauses in Breathing
Status: COMPLETED
Conditions: Sodium Imbalance|Nocturnal Blood Pressure|Obstructive Sleep Apnea of Adult
Interventions: BEHAVIORAL: Dietary sodium restriction
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Avera Cancer Sequencing and Analytics Protocol (ASAP)
Status: RECRUITING
Conditions: Cancer|Cancer Diagnosis|Early Detection of Cancer|Breast Cancer|Lung Cancer|Colon Cancer|GI Cancer|Gynecologic Cancer|Ovarian Cancer|Endometrial Cancer|CNS Cancer|Hematologic Cancer
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Implementation of Evidence-Based Treatment of Restrictive Eating Disorder With Pronounced Starvation
Status: RECRUITING
Conditions: Anorexia Nervosa|Anorexia Nervosa, Atypical|Avoidant/Restrictive Food Intake Disorder|Starvation
Interventions: BEHAVIORAL: Family Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Efficacy of VX-121 Combination Therapy in Subjects With Cystic Fibrosis
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: VX-121|DRUG: TEZ|DRUG: VX-561|DRUG: TEZ/IVA|DRUG: IVA|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Home-Delivered Attention Control Treatment for Post Traumatic Stress Disorder (PTSD)
Status: COMPLETED
Conditions: PTSD
Interventions: BEHAVIORAL: Attention Control Training (ACT)|BEHAVIORAL: Attention Bias Modification (ABM)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Formula on Growth of Infants From Overweight or Obese Mothers
Status: COMPLETED
Conditions: Infant Nutrition
Interventions: OTHER: standard infant formula|OTHER: Test formula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: An Investigation of a Multi-Function Skincare Product to Improve Aging, Eczema, and Acne Outcomes
Status: NOT_YET_RECRUITING
Conditions: Acne|Eczema|Skin Aging
Interventions: OTHER: Hemptress Oil
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Neoadjuvant Plus Adjuvant Treatment With Cemiplimab in Cutaneaous Squamous Cell Carcinoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Cutaneous Squamous Cell Carcinoma
Interventions: DRUG: Cemiplimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Restoring Masticatory Function to Treat Chronic Pain
Status: TERMINATED
Conditions: Temporomandibular Joint Dysfunction Syndrome|Chronic Pain
Interventions: PROCEDURE: Occlusal adjustment|PROCEDURE: Placebo occlusal adjustment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sensing Physiological Symptoms of Opioid Withdrawal and Cravings in Patients With Opioid Use Disorder
Status: NOT_YET_RECRUITING
Conditions: Opioid Withdrawal|Opioid Use Disorder
Interventions: DEVICE: EmbracePlus Smartwatch|DEVICE: Corti Sensor
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Iron Interventions and Non-transferrin-bound Iron (NTBI) in Women
Status: COMPLETED
Conditions: Iron Deficiency
Interventions: DIETARY_SUPPLEMENT: Ferrous sulfate|DIETARY_SUPPLEMENT: Ferrous sulfate|DIETARY_SUPPLEMENT: Ferrous sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Non-invasive Ultrasound Retinal Stimulation for Vision Restoration
Status: NOT_YET_RECRUITING
Conditions: Age-Related Macular Degeneration|Retinitis Pigmentosa|Ultrasound Therapy; Complications
Interventions: DEVICE: Non-invasive ultrasound retinal stimulation Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Zinc Absorption From SQ-LNS With and Without Phytase
Status: COMPLETED
Conditions: Individuals at Risk of Zinc Deficiency
Interventions: DIETARY_SUPPLEMENT: the nutritional supplement to be used in this trial is a SQ-LNS|DIETARY_SUPPLEMENT: lipid-based nutrient supplement (SQ-LNS) with phytase|DIETARY_SUPPLEMENT: 0.9 mg isotopically enriched 67Zn,0.30 mg isotopically enriched 70Zn, 0.60 mg non-enriched zinc|DIETARY_SUPPLEMENT: 1 mg isotopically enriched 68Zn
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Buprenorphine Transdermal Patches in Arthroscopic Rotator Cuff Repair
Status: COMPLETED
Conditions: Rotator Cuff Tear|Rotator Cuff Injury|Analgesics, Opioid|Buprenorphine
Interventions: DRUG: Buprenorphine|DRUG: Placebo Patch|DRUG: Multimodal Oral Scheme|DRUG: Tramadol|DRUG: Placebo Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: 3,4-Diaminopyridine for Lambert-Eaton Myasthenic Syndrome (LEMS) and Congenital Myasthenia (CM)
Status: NO_LONGER_AVAILABLE
Conditions: Lambert-Eaton Myasthenic Syndrome (LEMS)|Congenital Myasthenia (CM)
Interventions: DRUG: 3,4-diaminopyridine
Study Type: EXPANDED_ACCESS
Clinical trial: Indwelling Double-J Ureteral Stent Versus Externalized Modified-Salle Stent for Pyeloplasty
Status: TERMINATED
Conditions: Ureteropelvic Junction Obstruction
Interventions: OTHER: internal Double-J stents|OTHER: External Stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Rotational Stability of The AcrySof Toric Intraocular Lens in the Capsular Bag in High Myopic Subjects
Status: COMPLETED
Conditions: Cataract
Interventions: PROCEDURE: Cataract Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Sedation Strategies for Diagnostic Bronchoscopy
Status: TERMINATED
Conditions: Bronchoscopy|Sedation
Interventions: DRUG: Midazolam|DRUG: Dexmedetomidine|DRUG: Remifentanil|DRUG: Fentanyl|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sublingual Misoprostol to Reduce Blood Loss During Elective Cesarean Delivery
Status: UNKNOWN
Conditions: Hemorrhage Postpartum
Interventions: DRUG: Misoprostol Oral Tablet|DRUG: Ranitidine Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Veno-venous Extracorporeal CO2 Removal in ARDS-patients to Treat Respiratory Acidosis
Status: COMPLETED
Conditions: ACUTE RESPIRATORY DISTRESS SYNDROME
Interventions: PROCEDURE: extracorporeal removal of CO2 (ECCO2-R)|PROCEDURE: No extracorporeal CO2-removal
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prazosin for Smoking Cessation
Status: TERMINATED
Conditions: Nicotine Dependence
Interventions: DRUG: Placebo|DRUG: Prazosin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Accelerated Hypofractionated Whole Breast Irradiation Plus Sequential Boost Versus Concomitant Boost Following BCS
Status: UNKNOWN
Conditions: Radiotherapy Side Effect
Interventions: RADIATION: Sequential boost|RADIATION: Concomitant boost
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Trial to Evaluate Laparoscopy-assisted Nerve-preserved Total Mesorectal Excision (LNTME) Versus Open TME for Rectal Cancer
Status: UNKNOWN
Conditions: Rectal Cancer
Interventions: PROCEDURE: LNTME|PROCEDURE: OTME
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Compare Reduction in Pain After Surgery With and Without Local Anesthesia During Laparoscopy
Status: UNKNOWN
Conditions: Post Operative Pain
Interventions: DRUG: 0.25% bupivicaine will be injected at the study port site prior to incision|DRUG: Saline will be injected at the study port site prior to incision|DRUG: Saline will be in injected into the port site prior to closure|DRUG: 0.25% bupivicaine will be injected into the port site prior to closure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Palliative Re-irradiation for Progressive Diffuse Intrinsic Pontine Glioma (DIPG) in Children
Status: COMPLETED
Conditions: Pediatric Malignant Brain Tumor -Diffuse Intrinsic Pontine Glioma
Interventions: RADIATION: Palliative re-irradiation for progressive DIPG in children
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of T900607-Sodium in Chemotherapy Naive Patients With Hepatocellular Carcinoma.
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: intravenous T900607-sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Of CP-690,550 In Stable Kidney Transplant Patients
Status: COMPLETED
Conditions: Kidney Transplant
Interventions: DRUG: Placebo|DRUG: CP-690,550 5 mg BID|DRUG: CP-690,550 15 mg BID|DRUG: CP-690,550 30 mg BID
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety and Efficacy Study With Catumaxomab in Patients After Curative Resection of a Gastric Adenocarcinoma
Status: COMPLETED
Conditions: Gastric Cancer|Gastric Adenocarcinoma
Interventions: DRUG: catumaxomab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Investigate the Pharmacokinetic/Pharmacodynamic Drug-Drug Interaction of Pyrimethamine and Metformin IR
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Metformin and Pyrimethamine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Food Study of Glimepiride Tablets 1 mg to Amaryl® Tablets 1 mg
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Glimepiride Tablets 1 mg|DRUG: Amaryl® Tablets 1 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Liposomal-Cisplatin Analogue (L-NDDP) in Treating Patients With Malignant Pleural Mesothelioma
Status: COMPLETED
Conditions: Malignant Mesothelioma
Interventions: DRUG: liposomal NDDP|PROCEDURE: therapeutic thoracoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: STRATEGY for Left Main Coronary Bifurcation Lesion II
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DEVICE: One stent technique alone|DEVICE: One stent technique + Elective FKB|PROCEDURE: Provisional approach|DEVICE: Elective 2-stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacotherapy and Mechanisms of Sleep Disturbance in Alcohol Dependence
Status: COMPLETED
Conditions: Alcohol Dependence|Insomnia
Interventions: DRUG: Placebo dispensed to subject.|DRUG: Gabapentin dispensed to subject.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Evaluation of the Safety and Efficacy of Reformulated Raltegravir (MK-0518) 1200 mg Once Daily in Combination With TRUVADA™ in Human Immunodeficiency Virus (HIV)-1 Infected, Treatment-Naive Participants (MK-0518-292)
Status: COMPLETED
Conditions: HIV Infection
Interventions: DRUG: Reformulated Raltegravir|DRUG: Raltegravir|DRUG: TRUVADA™|DRUG: Placebo to Reformulated Raltegravir|DRUG: Placebo to Raltegravir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics Variability of Posaconazole (PCZ) and Its Glucuronide Metabolite During Induction and Consolidation Treatments in Patients With Acute Myeloid Leukemia (AML): a Covariate Analysis With the Tablets Formulation and Evaluation of the Potential Risk of Hepatotoxicity
Status: UNKNOWN
Conditions: Leukemia, Myeloid, Acute
Interventions: DRUG: Posaconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study of CM326 Injection in Healthy Subjects
Status: RECRUITING
Conditions: Healthy
Interventions: BIOLOGICAL: CM326|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Safety and Efficacy of OMS721 in Patients With Immunoglobulin A (IgA) Nephropathy
Status: TERMINATED
Conditions: IgA Nephropathy
Interventions: BIOLOGICAL: OMS721|OTHER: Vehicle (D5W or saline)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Proof of Concept of Adapted PD in Children (PC-AAPD)
Status: COMPLETED
Conditions: Primary Study Outcome: Sodium Clearance in Dialysis|Solute Removal|Ultrafiltration
Interventions: OTHER: Adapted double mini PET|OTHER: Standard double mini PET
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Low FODMAP Diet on Nutritional Status, Disease Activity and Gut Microbiota in IBS and UC With Normal or Overweight BMI
Status: UNKNOWN
Conditions: IBD - Inflammatory Bowel Disease|IBS - Irritable Bowel Syndrome|UC - Ulcerative Colitis
Interventions: OTHER: Low FODMAP diet|OTHER: Standard diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Conventional Repetitive Transcranial Magnetic Stimulation for Tinnitus Treatment
Status: COMPLETED
Conditions: Chronic Tinnitus
Interventions: DEVICE: transcranial magnetic stimulator (class 2b) Medtronic © MagPro X100 (with MagOption) stimulator and Butterfly Coil MCF-B65 (figure-8 coil with fluid cooling)|DEVICE: Sham transcranial magnetic stimulator Medtronic © MagPro X100 (shielded figure-8 coil with fluid cooling)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Enhancing Language Function in Aphasia
Status: RECRUITING
Conditions: Aphasia, Acquired|Language Disorders|Primary Progressive Aphasia|Stroke, Cerebrovascular
Interventions: BEHAVIORAL: individualized speech-language training|BEHAVIORAL: standard language intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Retinoic Acid Supplementation and Subjects With Hypercholesterolemia
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DIETARY_SUPPLEMENT: retinoic acid|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: eSET or eDET Associated to PGT in IVF
Status: COMPLETED
Conditions: in Vitro Fertilization|Single Embryo Transfer|Preimplantation Genetic Diagnosis|Pregnancy
Interventions: DIAGNOSTIC_TEST: preimplantation genetic test of embryo by new generation sequencing (NGS)|PROCEDURE: Single embryo transfer|PROCEDURE: Double embryo tranfer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Motivational Interviewing and Physical Activity Change in Parkinson's Disease
Status: UNKNOWN
Conditions: Parkinson Disease
Interventions: BEHAVIORAL: Motivational Interviewing|BEHAVIORAL: Web-based application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Cerclage for Twins With Short Cervix
Status: WITHDRAWN
Conditions: Preterm Birth|Preterm Labor With Preterm Delivery, Unspecified Trimester, Fetus 2|Cervical Incompetence|Cervical Shortening
Interventions: PROCEDURE: Cervical Cerclage placement|DRUG: Vaginal Progesterone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Losartan on the Incidence and Severity of Chemotherapy-Induced Mucositis in Gastrointestinal Cancer Patients
Status: RECRUITING
Conditions: Chemotherapy|Colorectal Cancer|Intestinal Mucositis|Oral Mucositis
Interventions: DRUG: Losartan 50mg Tab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Hyperbaric Prilocaine Compared With Hyperbaric Bupivacaine in Cervical Cerclage?
Status: RECRUITING
Conditions: Cervical Incompetence in Pregnancy as Antepartum Condition
Interventions: DRUG: Prilocaine (Hyperbaric 2%)|DRUG: Bupivacaine (Hyperbaric 0.5%)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 54135419SUI3002: A Study to Evaluate the Efficacy and Safety of Intranasal Esketamine in Addition to Comprehensive Standard of Care for the Rapid Reduction of the Symptoms of Major Depressive Disorder, Including Suicidal Ideation, in Adult Participants Assessed to be at Imminent Risk for Suicide
Status: COMPLETED
Conditions: Depressive Disorder, Major
Interventions: DRUG: Esketamine|DRUG: Placebo|OTHER: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of the eHealth Application "Cancer Patients Better Life Experience" (CAPABLE) - Italy
Status: COMPLETED
Conditions: Renal Cell Carcinoma Metastatic|Breast Cancer|Head and Neck Cancer|Thyroid Cancer|Ovary Cancer|Lung Cancer|Stomach Cancer
Interventions: DEVICE: CAPABLE cohort
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Osteopathic Manipulative Treatment and Postural Control: Systems Engineering Approach
Status: TERMINATED
Conditions: Low Back Pain
Interventions: PROCEDURE: Osteopathic manipulative treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Prehabilitation Effect on Function and Patient Satisfaction Following Total Knee Arthroplasty
Status: RECRUITING
Conditions: Prehabilitation|Knee Osteoarthritis
Interventions: BEHAVIORAL: Maximal strength training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effects of Anti-Inflammatory Treatment on Insulin Resistance in Healthy Volunteers
Status: COMPLETED
Conditions: Type 2 Diabetes|Diabetes
Interventions: DRUG: Salsalate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Safety Study of SEA-BCMA in Patients With Multiple Myeloma
Status: TERMINATED
Conditions: Multiple Myeloma
Interventions: DRUG: SEA-BCMA|DRUG: dexamethasone|DRUG: pomalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Responses of People With Neck Pain Being Treated With Varying Doses of Manual Therapy: A Pilot Study
Status: COMPLETED
Conditions: Whiplash Injuries
Interventions: BEHAVIORAL: Exercise and education once/week for 6 weeks|BEHAVIORAL: Exercise and education twice/week for 6 weeks|BEHAVIORAL: Exercise and education 3 times/week for 6 weeks|OTHER: Manual therapy once/week for 3 weeks|OTHER: Manual therapy twice/week for 3 weeks|OTHER: Manual therapy 3 times/week for 3 weeks|OTHER: Manual therapy once/week for 6 weeks|OTHER: Manual therapy twice/week for 6 weeks|OTHER: Manual therapy 3 times/week for 6 weeks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing Symbicort® As-Needed or Bricanyl As-Needed or Pulmicort® Once Daily + Bricanyl As-Needed in Asthma Patients
Status: COMPLETED
Conditions: Exercise Induced Asthma
Interventions: DRUG: budesonide|DRUG: terbutaline|DRUG: budesonide/formoterol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Efficacy and Safety of Boroda Supramolecular Active Zinc in the Treatment of Scalp Psoriasis
Status: COMPLETED
Conditions: Scalp Psoriasis
Interventions: OTHER: Boleda Supramolecular Active Zinc Conditioner|DRUG: Capotetriol scalp solution|OTHER: Supramolecular Hydrogel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Multiple Dose Escalation Study of ASKP1240 in Subjects With Moderate to Severe Plaque Psoriasis
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: ASKP1240|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Long-Term Treatment Study of ACH-0144471 in Participants With Paroxysmal Nocturnal Hemoglobinuria (PNH)
Status: COMPLETED
Conditions: Paroxysmal Nocturnal Hemoglobinuria
Interventions: DRUG: ACH-0144471
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Effectiveness of a Omega-3 Enriched Supplement on Chemotherapy Tolerance in Colon Cancer Patients
Status: TERMINATED
Conditions: Colorectal Neoplasms
Interventions: DIETARY_SUPPLEMENT: Eicosapentaenoic acid enriched nutritional supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Ceftolozane/Tazobactam vs. Piperacillin/Tazobactam for the Treatment of Bacteremia in Hemato-oncological Patients
Status: RECRUITING
Conditions: Hematologic Neoplasms|Neutropenia
Interventions: DRUG: Ceftolozane/tazobactam|DRUG: Piperacillin/tazobactam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Interest of Personalized Radiotherapy Dose Redistribution in Patients With Stage III NSCLC
Status: UNKNOWN
Conditions: Non-small Cell Lung Cancer
Interventions: RADIATION: Personalized dose redistribution|RADIATION: No personalized dose redistribution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Implementation of CAPABLE in the Michigan Medicaid Waiver
Status: COMPLETED
Conditions: Independent Living
Interventions: BEHAVIORAL: MiCAP with IF (Main Study)|BEHAVIORAL: MiCAP with IF and EF (Main Study)|BEHAVIORAL: MiCAP with IF and Caregiver Engagement (Administrative Supplement)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Carfilzomib With Bendamustine and Rituximab in Patients With Relapsed or Refractory Non-Hodgkin Lymphoma
Status: COMPLETED
Conditions: Lymphoma, Non-Hodgkin|Lymphoma
Interventions: DRUG: Carfilzomib|DRUG: Bendamustine|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Understanding HCV Reinfection Rates in an Incarcerated Population After Cure With Interferon Free HCV Treatment
Status: ACTIVE_NOT_RECRUITING
Conditions: Hepatitis C Virus
Interventions: DRUG: Paritaprevir|DRUG: Ritonavir|DRUG: Dasabuvir|DRUG: Ombitasvir|DRUG: Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vertebral Augmentation and Radiotherapy of Collapse Spinal Metastatic Cancer
Status: TERMINATED
Conditions: Metastatic Cancers|Multiple Myeloma|Vertebral Fracture
Interventions: PROCEDURE: Vertebroplasty|RADIATION: Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Walking in Pregnancy (WiP) - a Social Networking Physical Activity Intervention for Pregnant Obese Women
Status: COMPLETED
Conditions: Maternal Obesity Complicating Pregnancy|Maternal Obesity Complicating Childbirth
Interventions: BEHAVIORAL: walking and behavour change techniques
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Radiosurgery Treatment for Spasticity Associated With Stroke, SCI & Cerebral Palsy
Status: RECRUITING
Conditions: Spasticity as Sequela of Stroke|Spastic Cerebral Palsy|Spasticity, Muscle
Interventions: RADIATION: stereotactic radiosurgery (SRS) dorsal root rhizotomy radiomodulation|OTHER: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Thoracic Paravertebral Blocks in Open Nephrectomy
Status: COMPLETED
Conditions: Nephrectomy|Analgesia
Interventions: DRUG: Ropivacaine|DRUG: Morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Improvement of Quality of Life by Cannabinoids in Oncologic Patients
Status: NOT_YET_RECRUITING
Conditions: Medical Oncology|Palliative Care|Quality of Life|Cannabinoids
Interventions: DRUG: Cannabisextrakt Avextra 10/10 Lösung
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Thrombolysis or Anticoagulation for Cerebral Venous Thrombosis
Status: TERMINATED
Conditions: Sinus Thrombosis, Intracranial
Interventions: DRUG: Endovascular thrombolysis|DRUG: Heparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PET Scan Imaging in Assessing Response in Patients With Esophageal Cancer Receiving Combination Chemotherapy
Status: COMPLETED
Conditions: Adenocarcinoma of the Gastroesophageal Junction|Esophageal Cancer
Interventions: DRUG: Oxaliplatin|DRUG: Leucovorin Calcium|DRUG: Fluorouracil|DRUG: Carboplatin|DRUG: Paclitaxel|PROCEDURE: Positron Emission Tomography|PROCEDURE: Computed Tomography|RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral Fluency and the Response to Antidepressant Therapy in the Elderly With a Unipolar Depressive Episode
Status: UNKNOWN
Conditions: Unipolar Depression
Interventions: OTHER: Neuropsychological evaluations|OTHER: Psychiatric interview|OTHER: Cardiovascular risk assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Time-restricted Feeding for Treating Polycystic Ovary Syndrome (PCOS)
Status: COMPLETED
Conditions: Polycystic Ovary Syndrome|Overweight|Obesity
Interventions: BEHAVIORAL: Time-Restricted Feeding
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: G-CSF in Preventing Neutropenia in Women Receiving Chemotherapy for Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer|Chemotherapeutic Agent Toxicity|Neutropenia
Interventions: BIOLOGICAL: filgrastim
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Lacosamide's Effect on Calcitonin Gene-related Peptide in Migraine Patients
Status: COMPLETED
Conditions: Effect of Drug|Migraine Disorders
Interventions: DRUG: Lacosamide 50 MG Oral Tablet|DRUG: Ibuprofen 400 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Biomarkers in Blood and/or Tumor Tissue Samples From Patients With Ductal Carcinoma in Situ and From Healthy Volunteers
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: GENETIC: DNA analysis|GENETIC: polymorphism analysis|GENETIC: protein analysis|OTHER: laboratory biomarker analysis|OTHER: questionnaire administration|OTHER: survey administration
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Immunogenicity, Safety and Tolerability of Two Doses of FLUAD-H5N1 Influenza Vaccine in Adult and Elderly Subjects
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Pandemic influenza vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: PREVENTION
Clinical trial: The Treatment of Amyotrophic Lateral Sclerosis With Huollingshengji Granules
Status: UNKNOWN
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DRUG: Huolingshengji Granules|DRUG: Riluzole tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Safety Study of Mirikizumab (LY3074828)
Status: COMPLETED
Conditions: Psoriasis
Interventions: BIOLOGICAL: Mirikizumab- IV|BIOLOGICAL: Mirikizumab - SC|BIOLOGICAL: Placebo - IV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Stereotactic Radiosurgery and Systemic Dose Chemotherapy for Locally Advanced Lung Cancer
Status: UNKNOWN
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: Pemetrexed|DRUG: Carboplatin|DRUG: Cisplatin|DRUG: Docetaxel|DRUG: Paclitaxel|RADIATION: stereotactic radiosurgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Losartan on Retinal Endothelial Function in Patients With Essential Hypertension
Status: WITHDRAWN
Conditions: Hypertension
Interventions: DRUG: Losartan|DRUG: Metoprolol|DRUG: Losartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Ustekinumab in Pediatric Participants (U-POPS) With Juvenile Psoriatic Arthritis or Psoriasis
Status: COMPLETED
Conditions: Juvenile Psoriatic Arthritis|Psoriasis|Arthritis, Juvenile
Interventions: DRUG: Ustekinumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Combination Chemotherapy in Treating Patients With Advanced Prostate Cancer
Status: UNKNOWN
Conditions: Prostate Cancer
Interventions: DRUG: docetaxel|DRUG: estramustine phosphate sodium|DRUG: mitoxantrone hydrochloride|DRUG: prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Efficacy of Long-acting Octreotide (Sandostatin LAR) in Reducing Portal Pressure in Patients With Cirrhosis
Status: COMPLETED
Conditions: Cirrhosis|Portal Hypertension|Esophageal Varices
Interventions: DRUG: Long acting octreotide 10mg|DRUG: Long acting Octreotide 30mg|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of DLBS3233 in Prediabetic Patients
Status: COMPLETED
Conditions: Prediabetic
Interventions: DRUG: DLBS3233|DRUG: Placebo of DLBS3233
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Enasidenib and Azacitidine in Treating Patients With Recurrent or Refractory Acute Myeloid Leukemia and IDH2 Gene Mutation
Status: RECRUITING
Conditions: Acute Bilineal Leukemia|Acute Biphenotypic Leukemia|Chronic Myelomonocytic Leukemia|IDH2 Gene Mutation|Myelodysplastic Syndrome|Recurrent Acute Myeloid Leukemia|Refractory Acute Myeloid Leukemia
Interventions: DRUG: Azacitidine|DRUG: Enasidenib Mesylate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Telerehabilitation Through Serious Games in Virtual Reality in a Stroke Population (AutoRReVi)
Status: UNKNOWN
Conditions: Stroke|Hemiparesis|Cognitive Impairment|Healthy Subjects
Interventions: BEHAVIORAL: Motor and cognitive virtual reality-based assessments|BEHAVIORAL: Motor and cognitive virtual reality-based serious games
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Survivorship Care in Reducing Symptoms in Young Adult Cancer Survivors
Status: COMPLETED
Conditions: Breast Carcinoma|Cancer Survivor|Depression|Fatigue|Leukemia|Lymphoma|Malignant Bone Neoplasm|Malignant Digestive System Neoplasm|Malignant Female Reproductive System Neoplasm|Malignant Male Reproductive System Neoplasm|Pain|Sleep Disorder|Soft Tissue Sarcoma
Interventions: PROCEDURE: Management of Therapy Complications|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration|BEHAVIORAL: Telephone-Based Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Implantation of a Permanent Interatrial Shunt to Reduce Left Atrial Filling Pressures Following MitraClip
Status: RECRUITING
Conditions: Heart Failure|Mitral Regurgitation
Interventions: DEVICE: V-Wave Shunt Placement
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of CLSB With Sedation Versus General Endotracheal Anesthesia on Postoperative Outcomes in Elderly Patients Undergoing Hip Fracture Surgery
Status: UNKNOWN
Conditions: Anesthesia Morbidity|Anesthesia; Adverse Effect
Interventions: PROCEDURE: anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pleurectomy/ Decortication (P/D) Preceded or Followed by Chemotherapy in Patients With Early Stage MPM
Status: ACTIVE_NOT_RECRUITING
Conditions: Malignant Pleural Mesothelioma
Interventions: PROCEDURE: pleurectomy/decortication|DRUG: Pemetrexed/Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The SaeboGlove Evaluation Trial
Status: UNKNOWN
Conditions: Stroke|Cerebral Vascular Disorder|Brain Diseases|Central Nervous System Diseases|Nervous System Diseases|Vascular Diseases|Cardiovascular Diseases
Interventions: DEVICE: SaeboGlove
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Study on Fistuloplasty Using Flow Measurement Guidance
Status: TERMINATED
Conditions: End Stage Renal Failure on Dialysis|Renal Failure
Interventions: DEVICE: Using Flow measurements to guide fistula angioplasty (Transonics)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Efficacy, Pharmacokinetics, and Safety of Bolus Maintenance Doses of Org 9426 (Study P05976)(COMPLETED)
Status: COMPLETED
Conditions: Muscle Relaxation
Interventions: DRUG: Rocuronium bromide (Org 9426)|DRUG: Rocuronium bromide (Org 9426)|DRUG: Sevoflurane|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Qigong to Improve Frailty Among Older Cancer Survivors
Status: RECRUITING
Conditions: Cancer|Frailty|Survivorship|Elderly
Interventions: BEHAVIORAL: Qigong Baduanjin|BEHAVIORAL: Light flexibility exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Timing of Cord Clamping on Serum Calcium Levels in Neonates
Status: RECRUITING
Conditions: Serum Calcium Concentration
Interventions: PROCEDURE: Umblical Cord Clamping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy of Anti-GPRC5D CAR-T Cells Therapy in the Treatment of r/r MM
Status: RECRUITING
Conditions: Multiple Myeloma in Relapse|Multiple Myeloma, Refractory
Interventions: BIOLOGICAL: Anti-GPRC5D CAR-T Cells Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Combining Different Exercise Modes With CPT on Vascular Function and Sleep Quality in Female University Students With SD
Status: COMPLETED
Conditions: Sleep Quality|Vascular Function
Interventions: BEHAVIORAL: MICT + CPT, HIIT + CPT, SIT + CPT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Percutaneous Neuromodulation on Plasticity in the Somatosensory System in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: Ultrasound guided percutaneous neuromodulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Aripiprazole for Improving Side Effects of Clozapine in the Treatment of People With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia|Insulin Resistance
Interventions: DRUG: Aripiprazole|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison 1 Plane-1 Injection and 2 Plane-2 Injection Ultrasound-guided Supraclavicular Brachial Plexus Block
Status: COMPLETED
Conditions: Radius Fractures
Interventions: DEVICE: Stimuplex insulated needle|DRUG: lidocaine mixed with epinephrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Efficacy of Juniver, a Digital Self-help Intervention, on Symptoms of Eating Disorders: A Randomised Controlled Trial
Status: RECRUITING
Conditions: Feeding and Eating Disorders|Anorexia Nervosa|Bulimia Nervosa|Binge-Eating Disorder|Binge Eating|Eating Disorders|Disordered Eating
Interventions: OTHER: Juniver program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Estradiol's Effect on Brain Volume and Connectivity
Status: COMPLETED
Conditions: Emotion Regulation|Estradiol
Interventions: DRUG: Estradiol Valerate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Phase I Trial of a Recombinant COVID-19 Vaccine (CHO Cell)
Status: UNKNOWN
Conditions: COVID-19
Interventions: BIOLOGICAL: Two doses of middle-dose recombinant SARS-CoV-2 vaccine (CHO Cell) at the schedule of day 0, 14|BIOLOGICAL: Three doses of middle-dose recombinant SARS-CoV-2 vaccine (CHO Cell) at the schedule of day 0, 14, 28|BIOLOGICAL: Two doses of high-dose recombinant SARS-CoV-2 vaccine (CHO Cell) at the schedule of day 0, 14|BIOLOGICAL: Three doses of high-dose recombinant SARS-CoV-2 vaccine (CHO Cell) at the schedule of day 0, 14, 28|BIOLOGICAL: Two doses of placebo at the schedule of day 0, 14 #middle-dose group#|BIOLOGICAL: Three doses of placebo at the schedule of day 0, 14, 28 #middle-dose group#|BIOLOGICAL: Two doses of placebo at the schedule of day 0, 14 #High-dose group#|BIOLOGICAL: Three doses of placebo at the schedule of day 0, 14, 28 #High-dose group#
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Algorithm for Cervix Carcinoma Screening in CZ Using the Detection of HPV DNA and CINtec Plus
Status: COMPLETED
Conditions: Algorithm for Cervix Carcinoma Screening
Interventions: DIAGNOSTIC_TEST: HPV DNA test with selective HPV 16/18 genotyping (cobas® 4800 HPV Test, Roche)|DIAGNOSTIC_TEST: p16 and Ki-67 biomarker detection in the form of dual cytological staining (CINtec Plus, Roche)|DIAGNOSTIC_TEST: standard conventional cytology PAP test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pain Assessment During Chemo-Mechanical and Smart Burs Caries Removal Versus Atraumatic Restorative Treatment in Carious Primary Molars
Status: UNKNOWN
Conditions: Dental Caries in Children
Interventions: PROCEDURE: Atraumatic Restorative Treatment (ART)|PROCEDURE: Smart Burs|PROCEDURE: Chemo-Mechanical Caries Removal (CMCR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: To Compare the Pharmacokinetics of Tiotropium in Subjects With Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: COPD
Interventions: DRUG: Tiotropium HFA BAI 4.5 mcg|DRUG: Tiotropium HFA BAI 9.0 mcg|DRUG: SPIRIVA® HandiHaler® 18 mcg/day|DRUG: Spiriva® Respimat® 5 mcg/day
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT