pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Effect of Lithium Carbonate on Postoperative Sleep in Patients Undergoing Videoassisted Thoracic Surgery
Status: COMPLETED
Conditions: Sleep Deprivation
Interventions: DRUG: Lithium Carbonate 250 MG|DRUG: Calcium Carbonate 500 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: 0.2% Chx Gel vs Implant Bacterial Contamination
Status: UNKNOWN
Conditions: Bone Resorption|Bacteria Caused Disease
Interventions: DEVICE: placebo gel|DEVICE: 0.20% chlorhexidine gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Optimizing Rehabilitation for Phantom Limb Pain Using Mirror Therapy and Transcranial Direct Current Stimulation (tDCS)
Status: ACTIVE_NOT_RECRUITING
Conditions: Phantom Limb Pain|Amputation, Traumatic
Interventions: DEVICE: transcranial Direct Current Stimulation (tDCS): active (Soterix ©)|BEHAVIORAL: Mirror Therapy: active|DEVICE: transcranial Direct Current Stimulation (tDCS): sham (Soterix ©)|BEHAVIORAL: Mirror Therapy: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Quatro Study: Acceptability Study of (Placebo) Vaginal Delivery Forms for Preventing HIV and Unintended Pregnancy
Status: COMPLETED
Conditions: HIV|Contraception
Interventions: OTHER: HEC Placebo Gel|OTHER: Placebo Vaginal Insert|OTHER: Placebo Vaginal Film|OTHER: Placebo Intravaginal ring (IVR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Lung Pharmacokinetics (PK) in Epithelial Lining Fluid (ELF)
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Inhalation|DRUG: Systemic|OTHER: Bronchoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Evaluate the Efficacy, Safety, and Immunogenicity of mRNA-1647 Cytomegalovirus (CMV) Vaccine in Healthy Participants 16 to 40 Years of Age
Status: ACTIVE_NOT_RECRUITING
Conditions: Cytomegalovirus Infection
Interventions: BIOLOGICAL: mRNA-1647|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Pazopanib in the Treatment of Surgically Unresectable or Metastatic Chondrosarcoma
Status: COMPLETED
Conditions: Chondrosarcoma|Metastatic Chondrosarcoma
Interventions: DRUG: pazopanib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Camrelizumab Combined With Albumin-bound Paclitaxel and S-1 in the Treatment of Advanced Gastric Cancer
Status: UNKNOWN
Conditions: Advanced Gastric Adenocarcinoma
Interventions: OTHER: Camrelizumab, Albumin-bound paclitaxel, S-1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intra-arterial Microplasmin Administration in Patients With Acute Intracranial Vertebrobasilar Artery Occlusion
Status: TERMINATED
Conditions: Stroke
Interventions: DRUG: Microplasmin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Green Coffee Extract on Blood Glucose Homeostasis in Healthy Adults
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: 200mg GCE +200mg ALA|DIETARY_SUPPLEMENT: 200mg GCE +400mg ALA|DIETARY_SUPPLEMENT: 200mg GCE + 200mg DHB|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Autologous Bone Marrow-derived Mononuclear Cells for Therapeutic Arteriogenesis in Patients With Limb Ischemia
Status: UNKNOWN
Conditions: Intermittent Claudication|Peripheral Vascular Diseases
Interventions: BIOLOGICAL: bone marrow derived mononuclear cells|BIOLOGICAL: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Quetiapine XR Versus Divalproex on Clinical Outcome Quality of Sleep and Quality of Life in Bipolar Depression
Status: WITHDRAWN
Conditions: Bipolar Depression
Interventions: DRUG: Quetiapine fumarate|DRUG: Divalproex sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multicenter iTBS Neuromodulation for PTSD Treatment
Status: NOT_YET_RECRUITING
Conditions: Posttraumatic Stress Disorder
Interventions: DEVICE: sham stimulation|DEVICE: intermittent theta-burst stimulation (iTBS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of PEG-rhG-CSF Secondary Prophylaxis vs. Therapeutic Administration in Patients With Ovarian Cancer
Status: TERMINATED
Conditions: Adjuvant Chemotherapy|Ovarian Neoplasms|Ovarian Cancer
Interventions: DRUG: PEG-rhG-CSF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety and Efficacy Study of ZW25 (Zanidatamab) Plus Combination Chemotherapy in HER2-expressing Gastrointestinal Cancers, Including Gastroesophageal Adenocarcinoma, Biliary Tract Cancer, and Colorectal Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: HER2-expressing Gastrointestinal Cancers, Including Gastroesophageal Adenocarcinoma, Biliary Tract Cancer, and Colorectal Cancer
Interventions: DRUG: ZW25 (Zanidatamab)|DRUG: Capecitabine|DRUG: Cisplatin|DRUG: Fluorouracil|DRUG: Leucovorin|DRUG: Oxaliplatin|DRUG: Bevacizumab|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Continuous Temozolomide in Patients With Advanced or Metastatic Soft Tissue Sarcoma or Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer|Soft Tissue Sarcoma
Interventions: DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Pressure-controlled Ventilation on the Respiratory Complication in Patients Undergoing Laparoscopic Colectomy Compared With Volume-controlled Ventilation
Status: UNKNOWN
Conditions: Postoperative Respiratory Complication
Interventions: PROCEDURE: volume controlled ventilation|PROCEDURE: pressure controlled ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Towards a Post-exposition Pharmacological Prophylaxis for Post-traumatic Stress Disorder
Status: COMPLETED
Conditions: Intrusive Thought|Psychological Trauma|Inflammatory Response|Physiological Stress
Interventions: DRUG: Dexmedetomidine|DRUG: Gamma-Hydroxybutyrate|DRUG: Placebo|BEHAVIORAL: Experimental Model Trauma Film
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Oxytocin Administration to Therapists and Its Effects on Patient-perceived Attunement and Responsiveness
Status: NOT_YET_RECRUITING
Conditions: Mental Health Therapists
Interventions: DRUG: Oxytocin nasal spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Testing Integrative Smoking Cessation for HIV Patients
Status: RECRUITING
Conditions: Smoking|Smoking Cessation|HIV Infections
Interventions: DRUG: Nicotine Replacement Therapy|BEHAVIORAL: Mindfulness Training Smoking Cessation Intervention|BEHAVIORAL: Contingency Management Smoking Cessation Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study of Roxadustat (FG-4592) in Participants With End-Stage Renal Disease Receiving Maintenance Hemodialysis
Status: COMPLETED
Conditions: End Stage Renal Disease|Anemia
Interventions: DRUG: Roxadustat|DRUG: Epoetin Alfa|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Safety and Efficacy Study of Multiple Administration Regimens for Nivolumab Plus Ipilimumab in Subjects With Melanoma
Status: COMPLETED
Conditions: Melanoma
Interventions: BIOLOGICAL: Nivolumab|BIOLOGICAL: Ipilimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Troriluzole (BHV-4157) in Adult Participants With Obsessive Compulsive Disorder
Status: ACTIVE_NOT_RECRUITING
Conditions: Obsessive-Compulsive Disorder
Interventions: DRUG: Troriluzole|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cost- Effectiveness of a Face-to-Face Rehabilitation Program vs an Telemedicine Program in Chronic Low Back Pain
Status: COMPLETED
Conditions: Low Back Pain
Interventions: OTHER: Face-to-Face Rehabilitation program|OTHER: Telemedicine program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Acute Prucalopride Administration in Healthy Volunteers
Status: COMPLETED
Conditions: Molecular Mechanisms of Pharmacological Action|Depression|Depressive Disorder|Mood Disorders|Mental Disorder|Antidepressive Agents|Cognition
Interventions: DRUG: Prucalopride|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Epidermal Delivery of Ani-Aging Ingredients
Status: UNKNOWN
Conditions: Wrinkles|Acne Scars|Pigmentation
Interventions: DEVICE: Erbium 2940 plus cosmetics plus Impact|DEVICE: Erbium 2940 plus cosmetics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of QBW251 in Subjects With Bronchiectasis
Status: TERMINATED
Conditions: Bronchiectasis
Interventions: DRUG: Active drug|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of a Plant-based Hydrolysates Daily Consumption on the HbA1c of Pre-diabetic Subjects
Status: COMPLETED
Conditions: Pre-diabetes
Interventions: DIETARY_SUPPLEMENT: 12 weeks daily administration Cereal 1|DIETARY_SUPPLEMENT: 12 weeks daily administration Cereal 2|OTHER: 12 weeks daily administration Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of a New Technique -"IN-REC-SUR-E"- in Preterm Neonates With RDS
Status: COMPLETED
Conditions: Respiratory Distress Syndrome|Hyaline Membrane Disease
Interventions: DRUG: Poractant alfa, 200 mg/kg|DEVICE: Ventilator for High-frequency Oscillatory Ventilation (HFOV)|DEVICE: Nasal Continuous Positive Airway Pressure (nCPAP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Femoral Block in Elderly With Hip Fracture
Status: RECRUITING
Conditions: Hip Fractures
Interventions: PROCEDURE: femoral nerve catheter|DRUG: femoral group|DRUG: control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: TMS vs Conventional Therapy for the Treatment of Functional Neurological Non Epileptic Seizure Disorder
Status: COMPLETED
Conditions: Psychogenic Non-Epileptic Seizure
Interventions: DEVICE: Transcranial Magnetic Stimulation|DEVICE: Sham Transcranial Magnetic Stimulation coil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Opioid Free Anesthesia in Prolonged Surgery
Status: UNKNOWN
Conditions: Cancer, Bladder
Interventions: DRUG: INTRATHECAL dexmedetomidine INJECTION
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Exploring the Feasibility of a Digital Service to Improve Nutrition and Hydration Status of Older Adults
Status: RECRUITING
Conditions: Malnutrition|Healthy Aging|Dehydration
Interventions: DEVICE: Keep-on-Keep-Up Nutrition (KOKU-Nut)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Adjunctive Effects of Psilocybin and a Formulation of Buprenorphine
Status: RECRUITING
Conditions: Opioid Use Disorder
Interventions: DRUG: Psilocybin with facilitated counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Electrical Stimulation for Critically Ill Post-Covid-19 Patients
Status: COMPLETED
Conditions: COVID-19|Muscle Atrophy|Muscle Weakness
Interventions: DEVICE: Electrical Stimulation|DEVICE: Electrical Stimulation - Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: VR for Symptom Control and Wellbeing
Status: COMPLETED
Conditions: Oncology|End Stage Cancer|Palliative Care|Hematologic Malignancy
Interventions: DEVICE: Virtual Reality Headset to provide a Virtual Reality Experience
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Nurses' Health Study and Health Professionals Follow-Up Study (Dermatological Component)
Status: COMPLETED
Conditions: Skin Cancer|Melanoma|Non-melanoma Skin Cancer|Psoriasis|Rosacea|Lupus Erythematosus|Atopic Dermatitis
Interventions: OTHER: Nutrient Intake
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Is Hemodialysis Associated With Cardiac Markers Change?
Status: COMPLETED
Conditions: Renal Insufficiency, Chronic
Interventions: PROCEDURE: Hypothermic dialysis followed with routine dialysis|PROCEDURE: Routine dialysis followed with hypothermic dialysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Spray-Dried Solvent/Detergent-Treated Plasma for Infusion in Healthy Volunteers
Status: COMPLETED
Conditions: Coagulation Defects
Interventions: BIOLOGICAL: Spray-dried S/D-treated Plasma|DRUG: Spray-dried S/D-treated plasma|BIOLOGICAL: Spray-dried S/D-treated Plasma|BIOLOGICAL: Spray-dried S/D-treated Plasma|BIOLOGICAL: Spray-dried S/D-treated Plasma
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Effect of Magnetic Stimulation Repetitive Transcranial on Impulsivity in Cocaine Dependence
Status: UNKNOWN
Conditions: Cocaine Dependence
Interventions: PROCEDURE: Transcranial Magnetic Stimulation|PROCEDURE: Placebo TMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Single Dose Escalation Study to Investigate the Pharmacokinetics as Well as Safety and Tolerability of a Concomitant Administration of Nifedipne GITS and Candesartan Tablets Under Fasting Conditions in Healthy Male Subjects in an Open Label, Non-randomized, Sequential Design.
Status: COMPLETED
Conditions: Clinical Pharmacology
Interventions: DRUG: Nifedipine gastrointestinal therapeutic system (GITS) (Adalat LA, BAY a1040) + Candesartan cilexetil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hydroxychloroquine Administration for Reduction of Pexophagy
Status: COMPLETED
Conditions: Zellweger Syndrome|Peroxisome Biogenesis Disorders
Interventions: DRUG: Hydroxychloroquine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Single and Multiple Dose Escalation and Two-sequence Crossover Study of ONO-9054 in Patients With Ocular Hypertension or Mild Open-angle Glaucoma
Status: COMPLETED
Conditions: Ocular Hypertension (OHT)|Mild Open Angle-glaucoma (OAG)
Interventions: DRUG: ONO-9054|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Preoperative Buccal Misoprostol on Blood Loss in Second-trimester Dilation and Evacuation Abortion
Status: TERMINATED
Conditions: Abortion|Blood Loss
Interventions: DRUG: Misoprostol|OTHER: Folic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of a Smartphone Based Screening Tool for Neonatal Jaundice in Surabaya, Indonesia
Status: TERMINATED
Conditions: Jaundice, Neonatal
Interventions: DEVICE: Picterus Jaundice Pro
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Endocytoscopy for in Vivo Determination of Mucosal Inflammatory Cells and Intestinal Disease Activity in Inflammatory Bowel Disease (IBD)
Status: COMPLETED
Conditions: Crohn´s Disease|Ulcerative Colitis
Interventions: DEVICE: Endocytoscopy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study to Investigate the Pharmacokinetics and Safety and to Provide Proof of Mechanism of Alogabat in Children and Adolescents Aged 5-17 Years With Angelman Syndrome (AS) With Deletion Genotype.
Status: RECRUITING
Conditions: Angelman Syndrome
Interventions: DRUG: 60 mg QD Alogabat|DRUG: 40 mg QD Alogabat|DRUG: 7 mg QD Alogabat|DRUG: Part 2 Adult Alogabat High Dose (aged 15-17)|DRUG: Alogabat|DRUG: Alogabat|DRUG: Part 2 Optional Cohort
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Bond Strength,Microleakage and Clinical Performance of Three Pit and Fissure Sealants
Status: UNKNOWN
Conditions: Caries Prevention
Interventions: OTHER: Clinpro sealant|OTHER: Embrace wetbond sealant|OTHER: Triage sealant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Phase II Trial to Evaluate the Effect of Itraconazole on Pathologic Complete Response Rates in Resectable Esophageal Cancer
Status: NOT_YET_RECRUITING
Conditions: Esophageal Adenocarcinoma|Esophageal Squamous Cell Carcinoma|Gastroesophageal Junction Carcinoma
Interventions: DRUG: Itraconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Short Pulse and Q-switched ND-YAG Laser With Topical Carbon Versus Fractional CO2 Laser for Enlarged Facial Pores
Status: COMPLETED
Conditions: Skin Lesion
Interventions: DEVICE: short pulse and Q-switched ND-YAG laser with topical carbon|DEVICE: fractional CO2 laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Immunogenicity and Safety of GSK Biologicals' HPV GSK 580299 Vaccine in Healthy Chinese Female Subjects
Status: COMPLETED
Conditions: Infections, Papillomavirus
Interventions: BIOLOGICAL: HPV GSK 580299 vaccine|BIOLOGICAL: Placebo control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of JAK Inhibitor on Erosion Healing in RA
Status: RECRUITING
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Baricitinib 4 MG|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intraperitoneal Aerosolized Nanoliposomal Irinotecan (Nal-IRI) in Peritoneal Carcinomatosis From Gastrointestinal Cancer
Status: RECRUITING
Conditions: Peritoneal Carcinomatosis|Peritoneal Metastases|Colorectal Cancer|Small Bowel Cancer|Appendix Cancer|Gastric Cancer|Pancreatic Cancer|Bile Duct Cancer
Interventions: DRUG: PIPAC with Nal-IRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized, Placebo-Controlled, Two-Period, Crossover Study to Evaluate the Effect of Lurasidone HCl on Oral Contraceptive Pharmacokinetics in Healthy Female Subjects
Status: COMPLETED
Conditions: Pharmacokinetics
Interventions: DRUG: Lurasidone 40 mg|DRUG: Placebo 40 mg|DRUG: Ortho Tri-Cyclen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Clinical Study of Concurrent Pazopanib and Radiotherapy for Non-metastatic Sarcoma Patients
Status: TERMINATED
Conditions: Sarcoma|Soft Tissue Sarcomas
Interventions: RADIATION: external beam radiotherapy|DRUG: pazopanib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combo of Abraxane, TMZ, Bevacizumab in Metastatic Melanoma With Brain Metastases
Status: WITHDRAWN
Conditions: Metastatic Melanoma|Brain Metastases
Interventions: DRUG: nab-paclitaxel|DRUG: Temozolomide|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized Study of Olanzapine for the Prevention of CINV in Patients Receiving Moderately Emetogenic Chemotherapy
Status: UNKNOWN
Conditions: Cancer
Interventions: DRUG: Olanzapine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dexterous Partial Hand Prosthesis Outcomes
Status: COMPLETED
Conditions: Amputation|Amputation; Traumatic, Hand|Limb; Absence, Congenital, Upper|Prosthesis User|Upper Limb Amputation at the Hand
Interventions: DEVICE: Pointdexter
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Qigong for Pre-frail and Frail Older Cancer Survivors
Status: COMPLETED
Conditions: Cancer|Frailty
Interventions: BEHAVIORAL: Qigong|BEHAVIORAL: Light flexibility exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Prospective, Multicenter, Single Arm Feasibility Study of the Safety and Performance of GRADION™ Hip Total Cartilage Replacement (TCR)™ in the Treatment of Degenerative Joint Disease of the Hip
Status: TERMINATED
Conditions: Degenerative Joint Disease of the Hip
Interventions: DEVICE: GRADION™ Hip Total Cartilage Replacement (TCR)™
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Adenocarcinoma of the Rectum With Transanal Local Excision for Complete Responders
Status: RECRUITING
Conditions: Rectal Cancer
Interventions: PROCEDURE: Standard of care chemotherapy with the change for avoidance of extensive surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Human Umbilical Cord-derived Mesenchymal Stem Cells on Non-cardiac Surgery-induced Lung Injury
Status: RECRUITING
Conditions: Ischemic Heart Disease|Lung Injury|Non-cardiac Surgery
Interventions: BIOLOGICAL: human umbilical cord-derived mesenchymal stem cells|OTHER: saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bioavailability Mechanistic Study of Hot-Melt Extruded Amorphous Solid Dispersions
Status: COMPLETED
Conditions: Biological Availability|Amorphous Solid Dispersions
Interventions: DRUG: Hot-melt extruded amorphous solid dispersion of Efavirenz|DRUG: Hot-melt extruded amorphous solid dispersion of Efavirenz homogenized to drug rich particles|DRUG: Efavirenz solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety, Tolerability and PK of a Single Subcutaneous Injection of XmAb27564 in Healthy Volunteers
Status: COMPLETED
Conditions: Safety in Healthy Volunteers
Interventions: DRUG: XmAb27564|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Probiotics on Recurrent Urinary Tract Infections
Status: TERMINATED
Conditions: Urinary Tract Infections
Interventions: DIETARY_SUPPLEMENT: Food supplement|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Clinical Value of Sequential Gefitinib With Pemetrexed/Platinum for Advanced NSCLC
Status: COMPLETED
Conditions: NSCLC
Interventions: DRUG: Sequential Gefitinib With Pemetrexed/Platinum|DRUG: Pemetrexed/Platinum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Kampala Women's Bone Study
Status: COMPLETED
Conditions: Bone Demineralization|Hypoestrogenism|Subclinical Kidney Injury|Bone Microarchitecture
Interventions: COMBINATION_PRODUCT: FTC/TDF and DMPA|DRUG: FTC/TDF|DRUG: DMPA|OTHER: Neither DMPA nor FTC/TDF
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Strategies to Augment Ketosis: Optimization of Ketone Delivery Strategies
Status: RECRUITING
Conditions: Ketosis
Interventions: DIETARY_SUPPLEMENT: Ketone Supplement|BEHAVIORAL: Beverage Tolerability Questionnaire (BTQ) and satiety visual analogue scale|BIOLOGICAL: Blood Draw|OTHER: Breath Reading|OTHER: Heart Rate Variability|OTHER: CGM/CKM|RADIATION: DXA|OTHER: Urine Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Combined Cognitive Training With Aerobic Exercise in Stroke Patients With MCI
Status: UNKNOWN
Conditions: Stroke
Interventions: BEHAVIORAL: Aerobic exercise training|BEHAVIORAL: Computerized cognitive training|BEHAVIORAL: Control training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: HIV-Resistant Gene Modified Stem Cells and Chemotherapy in Treating Patients With Lymphoma With HIV Infection
Status: WITHDRAWN
Conditions: Human Immunodeficiency Virus 1 Positive|Stage I Adult Hodgkin Lymphoma|Stage I Adult Non-Hodgkin Lymphoma|Stage II Adult Hodgkin Lymphoma|Stage II Adult Non-Hodgkin Lymphoma|Stage III Adult Hodgkin Lymphoma|Stage III Adult Non-Hodgkin Lymphoma|Stage IV Adult Hodgkin Lymphoma|Stage IV Adult Non-Hodgkin Lymphoma
Interventions: BIOLOGICAL: C46/CCR5/P140K Lentiviral Vector-transduced Autologous HSPCs|DRUG: Carmustine|BIOLOGICAL: Filgrastim|OTHER: Laboratory Biomarker Analysis|DRUG: O6-Benzylguanine|DRUG: Plerixafor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Role of the Oral Microbiome & Mucosal Immunity in COVID-19 Disease
Status: RECRUITING
Conditions: COVID-19|Microbial Colonization|Oral Disease|Periodontal Diseases|Innate Inflammatory Response|Mucosal Infection
Interventions: BIOLOGICAL: COVID infection|BIOLOGICAL: COVID vaccination|DIAGNOSTIC_TEST: Oral examination
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Intracervical on the Pain Associated With the Insertion of the LNG-IUS
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Intracervical anesthesia with lidocaine 2%|DRUG: ibuprofen 400 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Priming Intravenous Rocuronium on Fentanyl-Induced Coughing
Status: COMPLETED
Conditions: Fentanyl-induced Coughing
Interventions: DRUG: Rocuronium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Immunogenicity of 30 and 100 µg of GMZ2 in Gabonese Children Aged 1-5 Years
Status: UNKNOWN
Conditions: Malaria
Interventions: BIOLOGICAL: GMZ 2 vaccine (GLURP + MSP 3)|BIOLOGICAL: GMZ 2 vaccine (GLURP + MSP 3)|BIOLOGICAL: Rabies vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Randomized Controlled Trial of Trauma-focused CBT in Tanzania and Kenya
Status: COMPLETED
Conditions: Childhood Traumatic Grief|Post Traumatic Stress|Post Traumatic Stress Disorder|Depressive Symptoms|Behavioral Problems|Child Overall Daily Functioning|Child and Guardian Relationship
Interventions: BEHAVIORAL: Trauma-focused Cognitive Behavioral Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacodynamic and Clinical Evaluation of Dose and Taste-optimised Low Volume PEG-based Bowel Cleansing Solutions Using the Split-dosing Intake Regimen in Healthy Subjects and in Subjects Undergoing Screening Colonoscopy
Status: COMPLETED
Conditions: Colon Cancer
Interventions: DRUG: NER1006|DRUG: MOVIPREP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of Verticalization on Bone Mineral Density and Biological Parameters of Bone Remodeling in Children With Severe Cerebral Palsy
Status: WITHDRAWN
Conditions: Cerebral Palsy|Osteoporosis|Bone Mineral Density|Bone Remodeling Disorder|Fracture
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: European Sleep Apnea and Sudden CArdiac Death ProjEct
Status: UNKNOWN
Conditions: Sleep Apnea|Sudden Cardiac Death|Heart Failure|Ischemic Cardiomyopathy
Interventions: DEVICE: Positive Airway Pressure Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Exploratory Clinical Study of GC012F Injection for Refractory gMG
Status: NOT_YET_RECRUITING
Conditions: Refractory Generalized Myasthenia Gravis
Interventions: DRUG: GC012F injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hypofractionated Stereotactic Body Radiation Therapy for Patients With Prostate Cancer That Was Removed by Surgery
Status: ACTIVE_NOT_RECRUITING
Conditions: Stage II Prostate Adenocarcinoma|Stage IIB Prostate Cancer|Stage III Prostate Adenocarcinoma
Interventions: OTHER: Laboratory Biomarker Analysis|OTHER: Quality-of-Life Assessment|RADIATION: Stereotactic Body Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Botulinum Toxin Injections in the Rectus Femoris to Treat Stiff Knee Gait Following Acquired Brain Injury
Status: TERMINATED
Conditions: Stiff Knee Gait|Brain Injuries
Interventions: DRUG: placebo|DRUG: botulinum toxin A (BTX-A)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Nifekalant Versus Amiodarone in New-Onset Atrial Fibrillation After Cardiac Surgery
Status: RECRUITING
Conditions: New Onset Atrial Fibrillation|Complications; Cardiac, Postoperative
Interventions: DRUG: Nifekalant|DRUG: Amiodarone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: S0334 Analyzing Chromosomes in Patients With Newly Diagnosed Multiple Myeloma or Other Blood Disease
Status: COMPLETED
Conditions: Lymphoma|Multiple Myeloma and Plasma Cell Neoplasm|Precancerous/Nonmalignant Condition
Interventions: GENETIC: cytogenetic analysis|GENETIC: fluorescence in situ hybridization
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pradaxa Tablet Proton Pump Inhibitor (PPI) Bioavailability (BA) Study in Japan
Status: COMPLETED
Conditions: Non-alcoholic Fatty Liver Disease
Interventions: DRUG: Dabigatran Etexilate|DRUG: Rabeprazol sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Effectiveness of Thoracic Epidural Analgesia for the Prevention of Acute Pancreatitis After ERCP Procedures
Status: COMPLETED
Conditions: Post-ERCP Acute Pancreatitis
Interventions: PROCEDURE: ERCP|PROCEDURE: Thoracic epidural analgesia|PROCEDURE: Premedication
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Carboplatin and Paclitaxel Albumin-Stabilized Nanoparticle Formulation Before Surgery in Treating Patients With Locally Advanced or Inflammatory Triple Negative Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Inflammatory Breast Cancer|Stage IIA Breast Cancer|Stage IIIA Breast Cancer|Stage IIIB Breast Cancer|Stage IIIC Breast Cancer|Triple-negative Breast Cancer|Stage IIB Breast Cancer|Estrogen Receptor Negative|Progesterone Receptor Negative|HER2/Neu Negative
Interventions: DRUG: carboplatin|DRUG: paclitaxel albumin-stabilized nanoparticle formulation|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Study of Long-acting and Short Acting Triptorelin in PCOS Patients Who Underwent IVF/ICSI
Status: UNKNOWN
Conditions: In Vitro Fertilization|Polycystic Ovary Syndrome
Interventions: DRUG: Long-acting Triptorelin|DRUG: Short-acting Triptorelin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Acute Effects of SGLT2 Inhibition on Renal Oxygenation and Autonomic Function in Type 1 Diabetes
Status: COMPLETED
Conditions: Nephropathy|Hypoxia|Mitochondrial Alteration|Type 1 Diabetes|Autonomic Neuropathy, Diabetic
Interventions: DRUG: Forxiga
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Impact of Robot Assisted Therapy and Metacognitive Skills Training for Children With Hemiparesis
Status: ACTIVE_NOT_RECRUITING
Conditions: Hemiparesis|Hemiplegic Cerebral Palsy|Hemiparesis;Poststroke/CVA
Interventions: DEVICE: Amadeo by Tyromotion|BEHAVIORAL: Active Learning Protocol for Stroke
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Forearm Shaft Fractures: Plating of Radius and Ulna Versus Plating of Radius and Nailing of Ulna
Status: TERMINATED
Conditions: Fractures of Radius and Ulna
Interventions: PROCEDURE: intramedullary nailing and plating|PROCEDURE: plating
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Examine the Safety, Tolerability and Effects on Abnormal Bone Formation of REGN2477 in Patients With Fibrodysplasia Ossificans Progressiva
Status: COMPLETED
Conditions: Fibrodysplasia Ossificans Progressiva
Interventions: DRUG: REGN2477|DRUG: Matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Association Between Renal Resistive Index(RRI) and AKI(Acute Kidney Injury) in Cardiac Surgery Patients With Cardiopulmonary Bypass (CPB)
Status: NOT_YET_RECRUITING
Conditions: Acute Kidney Injury|Renal Resistive Index
Interventions: PROCEDURE: Renal interlobar artery US|PROCEDURE: Renal inter-lobular artery US
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Metformin in Alzheimer's Dementia Prevention
Status: RECRUITING
Conditions: Mild Cognitive Impairment
Interventions: DRUG: Placebo oral tablet|DRUG: extended release metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Pilot Study to Determine the Efficacy of a Low Carbohydrate Diet in Treatment of Adolescents With Metabolic Syndrome
Status: COMPLETED
Conditions: Elevated Triglycerides|Systolic Hypertension|Insulin Resistance|Abdominal Obesity
Interventions: DIETARY_SUPPLEMENT: standard ADA diet|DIETARY_SUPPLEMENT: energy restricted very-low carbohydrate diet|DIETARY_SUPPLEMENT: low glycemic diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transcranial Magnetic Stimulation (TMS) for Motor Symptoms in Psychiatric Disorders
Status: COMPLETED
Conditions: Psychomotor Retardation|Psychomotor Slowing|Schizophrenia and Related Disorders|Major Depressive Disorder
Interventions: OTHER: DLPFC facilitatory|OTHER: SMA inhibitory|OTHER: SMA facilitatory|OTHER: sham TMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: QI Study of a Practice Facilitator's Impact in Working With Clinics on Improving Dental, Lead & Obesity Measures for Children
Status: COMPLETED
Conditions: Lead Poisoning|Obesity|Dental Decay
Interventions: OTHER: Practice-tailored intervention to increase rates of targeted services
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Three Different Programs of Paced Breathing in Treating Hot Flashes in Women
Status: COMPLETED
Conditions: Breast Cancer|Fatigue|Hot Flashes|Sleep Disorders
Interventions: BEHAVIORAL: Paced breathing (15 min once daily, 6 breaths/min)|BEHAVIORAL: Paced breathing (15 min twice daily, 6 breaths/min)|BEHAVIORAL: Paced breathing (10 min once daily, 14 breaths/min)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Extended-Release Buprenorphine vs. Sublingual Buprenorphine for the Treatment of Opioid Use Disorder
Status: SUSPENDED
Conditions: Opioid-use Disorder
Interventions: DRUG: extended-release buprenorphine (BXR)|DRUG: sublingual buprenorphine (BSL)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vibration Anesthesia for Propofol- Rocuronium Injection Pain
Status: COMPLETED
Conditions: Vibration|Pain Due to Certain Specified Procedures
Interventions: DEVICE: vibration device , Beauty bar facial massaging device, T-Shape Electric Sign Face Massage Tools, Dangshan, China
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effects of a Myofascial Technique on Biomechanical Properties of the Lumbar Myofascia of Chronic Low Back Pain Adults
Status: COMPLETED
Conditions: Chronic Low Back Pain
Interventions: OTHER: Myofascial release technique|OTHER: Simulated Myofascial Release technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Debriefing After a Short Training on Brief Tobacco Intervention for Nursing Students: A Randomized Clinical Trial
Status: COMPLETED
Conditions: Tobacco Cessation Competence
Interventions: OTHER: Debriefing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Examination of Efficacy and Safety of Baricitinib in RA Patients
Status: RECRUITING
Conditions: Rheumatoid Arthritis
Interventions: DRUG: "Baricitinib", "olumiant®"|DRUG: "Biologics"|DRUG: Tofacitinib 5 MG [Xeljanz]
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Assessment of the Intervention Effectiveness of Branched-chain Amino Acids(BCAA) Combined With Medium-chain Fatty Acid(MCFA) Products in Sarcopenia Among Middle-aged and Elderly Individuals
Status: RECRUITING
Conditions: Sarcopenia
Interventions: COMBINATION_PRODUCT: nutritional supplements
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of INBRX-106 and INBRX-106 in Combination With Pembrolizumab (Keytruda®) in Subjects With Locally Advanced or Metastatic Solid Tumors (Hexavalent OX40 Agonist)
Status: RECRUITING
Conditions: Solid Tumor|Non-Small Cell Lung Cancer|Head and Neck Cancer|Melanoma|Gastric Cancer|Renal Cell Carcinoma|Urothelial Carcinoma
Interventions: DRUG: INBRX-106 - Hexavalent OX40 agonist antibody|DRUG: pembrolizumab 200 mg|DRUG: pembrolizumab 400 mg|DRUG: Carboplatin AUC-5|DRUG: Carboplatin AUC-6|DRUG: Pemetrexed 500 mg/m2|DRUG: Cisplatin 75mg/m2|DRUG: Paclitaxel 200mg/m2|DRUG: Nab paclitaxel 100mg/m2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Evaluation of the Yes You Can... Make Smart Choices Curriculum
Status: RECRUITING
Conditions: Pregnancy in Adolescence|Adolescent Health
Interventions: BEHAVIORAL: Yes You Can…Make Smart Choices! (YYC…MSC!) program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Irradiation Doses < 10 Gy and of Irradiated Bone Volume on the Variation of Blood Elements of the Complete Blood Count During and After Pelvic Irradiation
Status: COMPLETED
Conditions: Prostate Carcinoma|Rectum Carcinoma|Anal Canal Carcinoma|Endometrium Carcinoma|Cervix Carcinoma|Radiotherapy|Vaginal Cancer
Interventions: OTHER: Biological investigations
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Ibritumomab Tiuxetan (Zevalin)+ Rituximab Maintenance
Status: TERMINATED
Conditions: Non-Hodgkin's Lymphoma
Interventions: DRUG: Ibritumomab Tiuxetan (Zevalin) + Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preventative Trial of Difluoromethylornithine (DFMO) in High Risk Patients With Neuroblastoma That is in Remission
Status: COMPLETED
Conditions: Neuroblastoma
Interventions: DRUG: DFMO
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Acupuncture as the Therapeutic Modalities of Acute Toxicity in the Radiotherapy of Head and Neck Tumors
Status: UNKNOWN
Conditions: Malignant Tumor of Soft Tissue of Head, Face and Neck
Interventions: OTHER: Acupuncture|DRUG: Standard supportive therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Excellence In Peripheral Artery Disease Thrombin Receptor Antagonist Intervention In Claudication Evaluation (XLPAD-TRACE Trial)
Status: UNKNOWN
Conditions: Peripheral Arterial Disease
Interventions: DRUG: Placebo + background APT + SMT|DRUG: Vorapaxar 2.08 mg/d + background APT + SMT.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Suture Repair of Lacerations in the ED: Comparison Between Two Suture Materials
Status: ENROLLING_BY_INVITATION
Conditions: Laceration of Hand|Laceration of Forearm
Interventions: DEVICE: Absorbable Surgical Gut Suture material|DEVICE: Non-absorbable Nylon Suture Material
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT