pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Retrospective, Observational, Noninterventional Data Collection Study for Patients With Molybdenum Cofactor Deficiency Who Have Been Previously Treated With Cyclic Pyranopterin Monophosphate (cPMP)
Status: COMPLETED
Conditions: Molybdenum Cofactor Deficiency
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study Comparing Blinatumomab Alternating With Low-intensity Chemotherapy Versus Standard of Care Chemotherapy for Older Adults With Newly Diagnosed Philadelphia-negative B-cell Precursor Acute Lymphoblastic Leukemia
Status: RECRUITING
Conditions: Newly Diagnosed Philadelphia (Ph)-Negative B-cell Precursor Acute Lymphoblastic Leukemia (ALL)
Interventions: DRUG: Blinatumomab|DRUG: Low-intensity chemotherapy regimen|DRUG: SOC chemotherapy regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Kefir on Appetite
Status: COMPLETED
Conditions: Appetitive Behavior
Interventions: OTHER: LGI-Milk Breakfast|OTHER: LGI-Kefir Breakfast|OTHER: HGI-Kefir Breakfast
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SCREENING
Clinical trial: CANTATA: CB-839 With Cabozantinib vs. Cabozantinib With Placebo in Patients With Metastatic Renal Cell Carcinoma
Status: COMPLETED
Conditions: Advanced Renal Cell Carcinoma|Metastatic Renal Cell Carcinoma
Interventions: DRUG: CB-839|DRUG: Cabozantinib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Erenumab (AMG 334) Plus Combined Oral Contraceptive Drug Interaction Study in Healthy Females
Status: COMPLETED
Conditions: Headache, Migraine
Interventions: DRUG: Erenumab|DRUG: Ethynil Estradiol/Norgestimate Oral Contraceptive
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study to Evaluate the Efficacy Safety and Tolerability of QR-421a in Subjects With RP Due to Mutations in Exon 13 of the USH2A Gene With Early to Moderate Vision Loss (Celeste)
Status: TERMINATED
Conditions: Retinitis Pigmentosa|Usher Syndrome Type 2|Deaf Blind|Retinal Disease|Eye Diseases|Eye Diseases, Hereditary|Eye Disorders Congenital|Vision Disorders
Interventions: DRUG: QR-421a|OTHER: Sham-procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Robot-Assisted Gait Therapy in the Subacute Phase of First Ischemic Stroke
Status: RECRUITING
Conditions: Ischemic Stroke
Interventions: PROCEDURE: Conventional rehabilitation|PROCEDURE: Leg/lower body exerciser device intervention.|PROCEDURE: Lokomat intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Boston Area Anticoagulation Trial for Atrial Fibrillation (BAATAF)
Status: COMPLETED
Conditions: Arrhythmia|Atrial Fibrillation|Cardiovascular Diseases|Cerebral Embolism and Thrombosis|Cerebrovascular Disorders|Heart Diseases|Thrombophlebitis|Cerebrovascular Accident
Interventions: DRUG: warfarin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: PREVENTION
Clinical trial: Evaluation of Discomfort Associated With Scleral Depression During Retina Examinations
Status: COMPLETED
Conditions: Retina--Diseases|Retinal Detachment|Retinal Degeneration
Interventions: DEVICE: Schocket scleral depressor|DEVICE: Cotton tipped applicator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety/Efficacy of Combo Therapy With Aliskiren & Hydrochlorothiazide vs Therapy With Hydrochlorothiazide Alone in Patients With Hypertension
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Aliskiren/HCTZ
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Two Different Methods of Physical Therapy to Treat Acute and Subacute Low Back Pain
Status: COMPLETED
Conditions: Low Back Pain
Interventions: BEHAVIORAL: Patient Education|PROCEDURE: Manual therapy of the thoracolumbosacral spine and hips|PROCEDURE: Motor control exercises|PROCEDURE: Treatment-Based Classification intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: NTX-301 in MDS/AML
Status: RECRUITING
Conditions: Acute Myeloid Leukemia|Myelodysplastic Syndromes|Chronic Myelomonocytic Leukemia
Interventions: DRUG: NTX-301
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare Treatment With the Drug Selumetinib Alone Versus Selumetinib and Vinblastine in Patients With Recurrent or Progressive Low-Grade Glioma
Status: RECRUITING
Conditions: Recurrent Low Grade Astrocytoma|Recurrent WHO Grade 2 Glioma|Refractory Low Grade Astrocytoma|Refractory Low Grade Glioma|Refractory WHO Grade 1 Glioma
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Magnetic Resonance Imaging|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration|DRUG: Selumetinib Sulfate|DRUG: Vinblastine Sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Correlation Between Changes in End-Tidal Carbon Dioxide and Stroke Volume Variation Detected by Electrical Cardiometry as A Predictor of Fluid Volume Responsiveness in Hemodynamically Unstable Patients in the Intensive Care
Status: COMPLETED
Conditions: End Tidal Carbon Dioxide|Cardiometry|Fluid Responsiveness|Shock
Interventions: DEVICE: end tidal carbon dioxide by capnography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of Lidocaine Spray Versus Dexmetomidine Spray on Stress Response
Status: RECRUITING
Conditions: To Measure Systolic Blood Pressure Postintubation
Interventions: DRUG: Normal saline, Lidocaine, dexmetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Alpine vs. Xpedition: Evaluation of Stent Delivery System
Status: UNKNOWN
Conditions: Percutaneous Coronary Intervention
Interventions: DEVICE: Stent delivery with Xpedition|DEVICE: Stent delivery with Alpine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Early Treatment of Language Impairment in Young Children With Autism Spectrum Disorder With Leucovorin Calcium
Status: RECRUITING
Conditions: Autism Spectrum Disorder|Language Disorders
Interventions: DRUG: Levoleucovorin Calcium|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Weight-Neutral Approach for a Healthier Lifestyle Among Obesity - A Lifestyle Intervention Anchored in SDOI
Status: ENROLLING_BY_INVITATION
Conditions: Health Related Quality of Life and Weight Condition
Interventions: BEHAVIORAL: Lifestyle Intervention|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Levonorgestrel-Releasing Intrauterine System (LNG-IUS) in the Management of Atypical Endometrial Hyperplasia
Status: WITHDRAWN
Conditions: Endometrial Hyperplasia
Interventions: DRUG: Megestrol Acetate|DRUG: Levonorgestrel Drug Implant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Psychological Impact of the Lockdown on Patients Giving Birth During the COVID-19 Epidemic Short Title : Isolement and Childbirth: Psychological Impact
Status: COMPLETED
Conditions: Post Partum Depression
Interventions: BEHAVIORAL: psychological assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Observation and Treatment of Pulmonary Microthrombosis in Childhood Pneumonia With Elevated D-dimer
Status: COMPLETED
Conditions: Pneumonia
Interventions: DRUG: Low-Molecular-Weight Heparins Calcium Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Financial Distress in Advanced Cancer Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Malignant Neoplasm|Locally Advanced Malignant Neoplasm|Metastatic Malignant Neoplasm|Recurrent Malignant Neoplasm|Refractory Malignant Neoplasm
Interventions: OTHER: Medical Chart Review|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Evaluate the Safety and Tolerability of SAGE-718 in Participants With Parkinson's Disease Mild Cognitive Impairment (PD-MCI)
Status: COMPLETED
Conditions: Parkinson Disease|Cognitive Dysfunction
Interventions: DRUG: SAGE-718
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Observational Trial of Real-World Treatment Utilization and Effectiveness of PI3K-inhibitors in CLL/SLL and FL
Status: TERMINATED
Conditions: Lymphoma, Small Lymphocytic|Lymphoma|Lymphoma, Non-Hodgkin|Chronic Lymphocytic Leukemia|Follicular Lymphoma
Interventions: DRUG: duvelisib|DRUG: PI3K inhibitor
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pre and Post-arterial Recanalization Imaging of Central Retinal Artery Occlusions (CRAO)
Status: RECRUITING
Conditions: Retinal Artery Occlusion|Magnetic Resonance Imaging|Diagnosis|Etiology|Prognosis
Interventions: DEVICE: Additional MRI sequences
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Study of Comparing the Efficacy and Safety of Human Umbilical Cord MSCs and Low-dose IL-2 in the Treatment of LN
Status: RECRUITING
Conditions: Systemic Lupus Erythematosus|Lupus Nephritis
Interventions: BIOLOGICAL: Human umbilical cord mesenchymal stem cells|DRUG: Interleukin-2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 17-N-Allylamino-17-Demethoxygeldanamycin and Paclitaxel in Treating Patients With Metastatic or Unresectable Solid Tumor
Status: COMPLETED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: tanespimycin|DRUG: paclitaxel|OTHER: laboratory biomarker analysis|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PK and Safety Study of BIIB074 in Healthy Japanese and Caucasian Participants
Status: COMPLETED
Conditions: Healthy|Trigeminal Neuralgia
Interventions: DRUG: BIIB074|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pixatimod (PG545) Plus Nivolumab in PD-1 Relapsed/Refractory Metastatic Melanoma and NSCLC and With Nivolumab and Low-dose Cyclophosphamide in MSS Metastatic Colorectal Carcinoma (mCRC)
Status: COMPLETED
Conditions: NSCLC|Metastatic Colorectal Carcinoma|Refractory Melanoma
Interventions: DRUG: Pixatimod|DRUG: Nivolumab|DRUG: Cyclophosphamide (low dose)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Efficacy, Safety, and Quality of Life of Pazopanib in Patients With Advanced and/or Metastatic Renal Cell Carcinoma After Prior Checkpoint Inhibitor Treatment
Status: COMPLETED
Conditions: Advanced Renal Cell Carcinoma|Metastatic Renal Cell Carcinoma
Interventions: DRUG: Pazopanib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: "Pontic-shield" Technique in Alveolar Ridge Preservation
Status: RECRUITING
Conditions: Tooth Extraction Status Nos|Bone Loss|Bone Resorption
Interventions: PROCEDURE: "Pontic-shield" technique|PROCEDURE: Alveolar ridge preservation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Palmitoylethanolamide Combined With Luteoline in Frontotemporal Dementia Patients. A Randomized Controlled Trial
Status: COMPLETED
Conditions: Frontotemporal Dementia
Interventions: DIETARY_SUPPLEMENT: PEA-LUT|DIETARY_SUPPLEMENT: PLACEBO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Treating Depression With Transcutaneous Electrical Cranial-auricular Acupoint Stimulation (TECAS).
Status: COMPLETED
Conditions: Mild-to-moderate Depression
Interventions: PROCEDURE: TECAS Procedure|DRUG: Escitalopram|DRUG: Insomnia medication
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Four-Arm Study Comparing the Analgesic Efficacy and Safety of Tramadol Once a Day 100, 200 and 300 mg Versus Placebo for the Treatment of Pain Due to Osteoarthritis of the Knee (With 7-Day Follow-up)
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Tramadol Once A Day|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Methocarbamol vs Oxybutynin for Management of Pain and Discomfort S/P Ureteroscopy Procedure
Status: RECRUITING
Conditions: Kidney Calculi|Kidney Diseases|Nephrolithiasis|Urolithiasis|Ureteral Diseases|Ureteral Calculi
Interventions: DRUG: Methocarbamol|DRUG: Oxybutynin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Dry Eye Disease Using Pro-ocular™ - A Proof of Concept, Safety, and Efficacy Study
Status: UNKNOWN
Conditions: Dry Eye Syndrome|Keratoconjunctivitis Sicca
Interventions: DRUG: Pro-ocular™ Topical Gel|DRUG: Placebo Topical Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Norepinephrine and Phenylephrine, Which Better for Elderly?
Status: UNKNOWN
Conditions: Hypotension
Interventions: DRUG: norepinephrine|DRUG: Phenylephrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Development and Validation of an Investigator Global Assessment Score for Keratosis Pilaris
Status: UNKNOWN
Conditions: Keratosis Pilaris
Interventions: OTHER: CeraVe SA Smoothing Cleanser|OTHER: CeraVe SA Smoothing Cream|OTHER: Propaira 20% Lactic Acid Exfoliating Lotion|OTHER: Propaira 30% Urea Exfoliating Emollient|OTHER: KPAI|OTHER: KP-IGA
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Augmented Reality Based Telerehabilitation Application on Neuromuscular and Sensorimotor Parameters in Multiple Sclerosis Patients
Status: NOT_YET_RECRUITING
Conditions: Multiple Sclerosis
Interventions: OTHER: Augmented Reality Based Telerehabilitation Application|OTHER: Training face-to-face
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Echoguided Percutaneous Neuromodulation in the Management of Chronic Ankle Instability in Physically Active Subjects.
Status: RECRUITING
Conditions: Transcutaneous Electric Nerve Stimulation|Ankle Injuries and Disorders : Chronic Ankle Instability|Exercise Therapy
Interventions: PROCEDURE: Echoguided percutaneous neuromodulation plus exercise|PROCEDURE: Strength program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Prospective Study to Evaluate the Raindrop Near Vision Inlay With Mitomycin C
Status: UNKNOWN
Conditions: Presbyopia
Interventions: DRUG: Mitomycin C|DEVICE: Raindrop Near Vision Inlay
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Achieving Sustained Early Child Development Impacts at Scale: A Test in Kenya
Status: RECRUITING
Conditions: Child Development|Child Behavior|Language, Child
Interventions: BEHAVIORAL: Msingi Bora responsive parenting and family wellbeing program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Treatment With Metformin and Combination of Metformin and Pioglitazone in Polycystic Ovarian Syndrome
Status: COMPLETED
Conditions: Polycystic Ovarian Syndrome
Interventions: DRUG: Metformin|DRUG: Metformin, Pioglitazone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study Comparing Early and Late Nutrition in Cancer Patients Undergoing Abdominal Surgery
Status: UNKNOWN
Conditions: Cancer|Abdominal Surgery|Parenteral Nutrition
Interventions: DIETARY_SUPPLEMENT: Early parenteral nutrition|DIETARY_SUPPLEMENT: Late parenteral nutrition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Physical Activity Intervention on Overweight and Obese Patients With Endometrial Cancer
Status: COMPLETED
Conditions: Endometrium Cancer|Physical Activity|Weight Management
Interventions: BEHAVIORAL: Physical activity
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trigeminal Nerve Stimulation for Post Traumatic Stress Disorder (PTSD) and Depression
Status: COMPLETED
Conditions: Depression|Post-traumatic Stress Disorder
Interventions: PROCEDURE: Transcutaneous Electrical Nerve Stimulator (TENS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Can the Osteopathic Pedal Pump Reduce Lymphedema in the Lower Extremities in the Elderly? A Mentorship Project.
Status: COMPLETED
Conditions: Lymphedema, Lower Limb
Interventions: OTHER: Osteopathic manipulative medicine pedal pump
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Skin Cleansers on the Skin Surface Microbiome
Status: COMPLETED
Conditions: Skin Health
Interventions: DRUG: 7.5% Povidone-Iodine [PVP-I]|DRUG: 4% chlorhexidine skin cleanser|DRUG: Plain non antibacterial soap
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of the Efficacy and Safety of the Dermal Filler for Augmentation of Labia Majora.
Status: COMPLETED
Conditions: Labia Majora Atrophy and Hypotrophy
Interventions: DEVICE: MMI-22-04-2019
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lenvatinib Plus Tislelizumab With or Without TACE in First-line Treatment of Unresectable HCC
Status: RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Lenvatinib Plus Tislelizumab|DEVICE: Transarterial Chemoembolization(TACE)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial to Learn More About How BAY2327949 Works and How Safe it is in Patients Whose Kidneys Are Damaged Due to High Blood Sugar Levels or High Blood Pressures, and With a Further Disease of the Heart or the Blood Vessels.
Status: WITHDRAWN
Conditions: Chronic Kidney Disease|Diabetic Kidney Disease
Interventions: DRUG: BAY2327949|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Views on Cancer Prevention and Daily Lifestyle
Status: COMPLETED
Conditions: Colorectal Cancer|Sedentary Lifestyle
Interventions: BEHAVIORAL: Common-Sense Model (CSM) Be Well|BEHAVIORAL: ACS usual messages|BEHAVIORAL: NCI HealthyYouTXT--Get Active (HYT--GA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Enriched Honey With Soluble Fiber and Polyphenols on Satiety and Dyslipidemia
Status: COMPLETED
Conditions: Overweight and Obesity|Dyslipidemias
Interventions: DIETARY_SUPPLEMENT: Control honey|DIETARY_SUPPLEMENT: Modified honey with soluble fiber and polyphenols
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: A Clinical Study to Evaluate the Safety and Effectiveness of an Investigational Product Called CT Gel
Status: COMPLETED
Conditions: Acne Vulgaris|Acne
Interventions: DRUG: CT Gel|DRUG: Clindamycin Gel (clindamycin )|DRUG: Tretinoin Gel (tretinoin)|DRUG: Vehicle Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial of Durvalumab (MEDI4736) as 1st Line Therapy in Advanced Non-small Cell Lung Cancer Patients
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer NSCLC
Interventions: DRUG: durvalumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Web-Based Tailored Educational Program in Improving Nurse Communication With Patients About Clinical Trials
Status: COMPLETED
Conditions: Healthy, no Evidence of Disease
Interventions: OTHER: IMPACT intervention|OTHER: Online education materials|OTHER: survey administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effectiveness of Protein Supplementation on Frailty Improvement, Muscle Strength and Physical Performance Among Pre-Frail Elderly People
Status: NOT_YET_RECRUITING
Conditions: Frailty|Muscle Weakness|Physical Dependence|Weight Loss
Interventions: DIETARY_SUPPLEMENT: SUSTINEX Hydrolyzed Whey Protein
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Genomic Markers Before and After Treatment of Actinic Keratosis With Imiquimod 3.75% Cream
Status: COMPLETED
Conditions: Actinic Keratosis
Interventions: DRUG: Imiquimod 3.75% Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MT2021-08T Cell Receptor Alpha/Beta Depletion PBSC Transplantation for Heme Malignancies
Status: RECRUITING
Conditions: Hematologic Malignancy|Acute Leukemia|Remission|Acute Myeloid Leukemia|Acute Lymphoblastic Leukemia|AML|TP53|Intrachromosomal Amplification of Chromosome 21|Cytogenetic Abnormality|CNS Leukemia|Minimal Residual Disease|Myelodysplasia|Juvenile Myelomonocytic Leukemia|Somatic Mutation|PTPN11 Gene Mutation|N-RAS Gene Amplification|Neurofibromatosis 1|NF1 Mutation|CBL Gene Mutation|Monosomy 7|Chromosome Abnormality|Fetal Hemoglobin
Interventions: DRUG: Fludarabine|DRUG: Busulfan|DRUG: Melphalan|DRUG: Rituximab|DRUG: Levetiracetam
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cosmetic Study of AO+Mist in Improving the Appearance of Skin Afflicted With Keratosis Pilaris
Status: COMPLETED
Conditions: Keratosis Pilaris
Interventions: OTHER: Placebo|OTHER: AO+Mist
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: OTHER
Clinical trial: RHAPSODY-plus: Online Counseling for Family Caregivers of Patients With Young Onset Dementia
Status: COMPLETED
Conditions: Early Onset Alzheimer Disease|Frontotemporal Dementia
Interventions: DEVICE: RHAPSODY online program and MEET online sessions
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study to Evaluate HT-4253 in Healthy Subjects
Status: NOT_YET_RECRUITING
Conditions: Normal Healthy Subjects
Interventions: DRUG: HT-4253|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Description Des Troubles Respiratoires Chez Les Patients Suivis Pour Une Sclérose en Plaques (SEP) sévère
Status: UNKNOWN
Conditions: Multiple Sclerosis|Respiration Disorders
Interventions: DIAGNOSTIC_TEST: Polysomnography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Malignant Mesothelioma - Can we Improve Quality of Life
Status: COMPLETED
Conditions: Mesothelioma, Malignant
Interventions: OTHER: Regular Early Specialist Symptom Control Treatment (RESSCT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Maturation of Arteriovenous Fistula With Automated Sonography Assessments Trial
Status: RECRUITING
Conditions: Diabetes|End Stage Renal Disease
Interventions: DEVICE: EchoMark/EchoSure|PROCEDURE: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Medical Food for Chronic Wounds
Status: COMPLETED
Conditions: Foot Ulcer, Diabetic
Interventions: OTHER: Medical Food|OTHER: Drink mix calorically similar to experimental product
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial Evaluating the Addition of Nivolumab to Cisplatin-RT for Treatment of Cancers of the Head and Neck
Status: ACTIVE_NOT_RECRUITING
Conditions: Squamous Cell Carcinoma of Head and Neck
Interventions: DRUG: Cisplatin|DRUG: Nivolumab|RADIATION: RT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ORANGE SEGMENTS: Open Versus Laparoscopic Parenchymal Preserving Postero-Superior Liver Segment Resection
Status: ACTIVE_NOT_RECRUITING
Conditions: Liver Surgery
Interventions: PROCEDURE: Parenchymal preserving postero-superior liver segment resection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study To Assess The Efficacy Of A Cholesterol Lowering Drug On Top Of Statins In Patients After Myocardial Infarction (MI)(0653A-150)
Status: COMPLETED
Conditions: Cardiovascular Disorder
Interventions: DRUG: Ezetimibe|DRUG: simvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Riboflavin Mediated Corneal Crosslinking for Stabilizing Progression of Keratoconus
Status: COMPLETED
Conditions: Keratoconus
Interventions: PROCEDURE: Riboflavin/UVA crosslinking|PROCEDURE: Sham treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase III Clinical Study Evaluating the Efficacy and Safety of WPV01 in Patients With Mild/Moderate COVID-19
Status: COMPLETED
Conditions: Mild to Moderate COVID-19
Interventions: DRUG: WPV01|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Open-Label Access Protocol of Denosumab for Subjects With Advanced Cancer
Status: COMPLETED
Conditions: Bone Metastases in Men With Hormone-Refractory Prostate Cancer|Bone Metastases in Subjects With Advanced Breast Cancer
Interventions: DRUG: Denosumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Light Therapy in the Treatment of Non-seasonal Depressive Disorder in Chinese Population
Status: UNKNOWN
Conditions: Major Depressive Disorder
Interventions: DEVICE: Light terapy|DEVICE: pseudo-light therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Aerosolized Colistin to Mechanical Ventilated Patients With Pneumonia
Status: COMPLETED
Conditions: Pneumonia, Bacterial
Interventions: DEVICE: A pneumatic nebulizer|DEVICE: A vibrating mesh nebulizer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Regulating Blood Pressure During Recovery from Intracerebral Hemorrhage and Ischemic Stroke
Status: RECRUITING
Conditions: Intracerebral Hemorrhage|Ischemic Stroke|Spironolactone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Fluconazole and Amphotericin B in the Treatment of Brain Infections in Patients With AIDS
Status: COMPLETED
Conditions: Meningitis, Cryptococcal|HIV Infections
Interventions: DRUG: Fluconazole|DRUG: Amphotericin B
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: A Technological Approach to Improved Breastfeeding Rates and Self-Efficacy
Status: COMPLETED
Conditions: Breastfeeding
Interventions: OTHER: "Breastfeeding at AU" Smartphone Application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Exploratory Study on Combined Conversion Immunotherapy for Liver Metastasis of MSS Type Initial Unresectable Colorectal Cancer Based on Gene Status
Status: UNKNOWN
Conditions: Colorectal Cancer|Liver Metastases
Interventions: DRUG: Experimental drug
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial of SHR-2002 Injection or Combined With Other Anti-cancer Medication in Advanced Malignant Tumors of Patients
Status: UNKNOWN
Conditions: Advanced Malignant Tumors
Interventions: DRUG: SHR-2002 injection、Camrelizumab for Injection, SHR-1316 injection, SHR-1701 injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Total Laparoscopic Versus Laparoscopic Assisted Left-sided Colon Cancer Resection
Status: RECRUITING
Conditions: Colon Cancer
Interventions: PROCEDURE: laparoscopic assisted left colectomy|PROCEDURE: total laparoscopic left colectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Myoring Versus Keraring Implantation for Keratoconus
Status: UNKNOWN
Conditions: Keratoconus
Interventions: OTHER: intrastromal corneal ring segments (Keraring) implantation|OTHER: Intrastromal corneal continuous ring (Myoring) implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: Anti-insulin-like Growth Factor-1 Receptor (IGF-1R) Antibodies in Graves' Disease and Graves' Orbitopathy
Status: COMPLETED
Conditions: Graves Ophthalmopathy|Graves Disease|Autoimmune Thyroiditis
Interventions: DIAGNOSTIC_TEST: Serum antibodies against the IGF-1R
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of the Respimat Inhaler vs. a HFA MDI Using Berodual in Patients With COPD With Poor MDI Technique.
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive|Asthma
Interventions: DEVICE: Berodual Respimat|DEVICE: Berodual HFA-MDI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Implementation of a Pilot Telerehabilitation Network in Pediatric Patients With Complex Neurodisabilities MedeaNeuroTelerehab-Net (MENTE.NET Study)
Status: COMPLETED
Conditions: Neurological Diseases or Conditions
Interventions: DEVICE: Khymeia VRRS
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Almonertinib Plus Chemotherapy as First-line Treatment in Patients With EGFR Concomitant Tumor Suppressor Gene Mutation
Status: UNKNOWN
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: Almonertinib|DRUG: Almonertinib plus carboplatin and pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Camrelizumab Combined With Bevacizumab and HAIC in Patients With Metastatic Liver Cancer Who Failed Standard Therapy
Status: NOT_YET_RECRUITING
Conditions: Metastatic Liver Cancer
Interventions: DRUG: HAIC、Bevacizumab、Camrelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare the Effectiveness and Safety of Flexibly Varied Doses of Paliperidone Palmitate and Risperidone in Treating Patients With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: paliperidone palmitate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of a Continent Cutaneous Urinary Diversion in Spinal Cord Injury Patients
Status: UNKNOWN
Conditions: Spinal Cord Injuries|Urinary Diversion|Neurogenic Bladder
Interventions: OTHER: Data collection|OTHER: Interview using a validated questionnaire
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Determining How Quickly Progesterone Slows LH Pulse Frequency
Status: COMPLETED
Conditions: Normal|PCOS
Interventions: DRUG: oral micronized progesterone suspension|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Study Examining PrEP-001 in Subjects With Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: PrEP-001|DRUG: G-004
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Cognitive Training in Heart Failure Study (CogTrain-HF)
Status: COMPLETED
Conditions: Congestive Heart Failure|Cognitive Impairment
Interventions: BEHAVIORAL: Cognitive training|BEHAVIORAL: Test of general knowledge
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Dapagliflozin in Non-diabetic Stage IV CKD
Status: COMPLETED
Conditions: Chronic Kidney Diseases
Interventions: DRUG: Dapagliflozin 10Mg Tab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Azithromycin (AZ) and Sulphadoxine-pyrimethamine (SP) for Malaria Prevention in Pregnant Women (IPT-AZ/IPT-SP)
Status: UNKNOWN
Conditions: Malaria in Pregnancy|Pregnancy
Interventions: DRUG: Sulfadoxine pyrimethamine|DRUG: Azithromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Levodopa and Exercise for Older Adults With Depression and Psychomotor Slowing
Status: TERMINATED
Conditions: Depressive Disorder
Interventions: DRUG: Carbidopa/levodopa|DRUG: Placebo|BEHAVIORAL: Exercise training|BEHAVIORAL: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Study to Explore the Cardiac Pharmacodynamics of MT-1303
Status: COMPLETED
Conditions: Relapsing-remitting Multiple Sclerosis
Interventions: DRUG: MT-1303-Low|DRUG: MT-1303-High|DRUG: Fingolimod|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose:
Clinical trial: Clinical Evaluation of the Fracture Resistance for E-max Cad and Vita Suprinity Laminate Veneers
Status: UNKNOWN
Conditions: Tooth Discoloration
Interventions: OTHER: Vita suprinity|OTHER: Emax CAD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of a Wide Spectrum Nutritional Supplement on Mitochondrial Function in Children With Autism Spectrum Disorder
Status: ACTIVE_NOT_RECRUITING
Conditions: Autism Spectrum Disorder
Interventions: DRUG: Wide-spectrum nutritional supplement|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Benefits of Implantable Cardioverter Defibrillator Follow-up Using Remote Monitoring
Status: COMPLETED
Conditions: Implantable Cardioverter-Defibrillators|Ventricular Fibrillation|Tachycardia, Ventricular
Interventions: OTHER: ACTIVATION of HOME MONITORING
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: An Open-label, Study to Assess Safety, Efficacy and Cellular Kinetics of YTB323 in Severe, Refractory Systemic Lupus Erythematosus
Status: RECRUITING
Conditions: Systemic Lupus Erythematosus|Lupus Nephritis
Interventions: DRUG: YTB323
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: First-In-Human Study Of Single And Multiple Ascending Doses Of PF-06751979
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: PF-06751979 single ascending dose|DRUG: Placebo single dose|DRUG: PF-06751979 multiple ascending dose|DRUG: Placebo multiple dose|DRUG: PF-06751979 multiple dose|DRUG: PF-06751979 multiple dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Bupivacaine/Epinephrine +Dexamethasone vs. Liposomal Bupivacaine
Status: RECRUITING
Conditions: Robotic Lung Surgery
Interventions: DRUG: Intercostal nerve block and wound infiltration with liposomal bupivacaine|DRUG: Intercostal nerve block and wound infiltration with bupivacaine/epinephrine + dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of AK111 in Subjects With Moderate-to-severe Plaque Psoriasis
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: AK111|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SkinPen Efficacy on Acne Scars on the Face and/or Back
Status: COMPLETED
Conditions: Atrophic Acne Scar
Interventions: PROCEDURE: Aesthetic Microneedling Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study on the Usability of the Needle-free Intraject® System in Adult Patients During Acute Migraine Attack
Status: COMPLETED
Conditions: Migraine Headache
Interventions: DEVICE: Intraject Sumatriptan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Efficacy of Transcutaneous Versus Percutaneous Posterior Tibial Nerve Stimulation in the Overactive Bladder.
Status: UNKNOWN
Conditions: Overactive Bladder Syndrome
Interventions: DEVICE: Transcutaneous tibial nerve stimulation|DEVICE: Percutaneous tibial nerve stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Low Pressure Pneumoperitoneum and Postoperative Ileus
Status: NOT_YET_RECRUITING
Conditions: Postoperative Ileus|Gastrointestinal Dysfunction
Interventions: PROCEDURE: Pneumoperitoneum Pressure|PROCEDURE: Neuromuscular blockade|DEVICE: Pneumoperitoneum insufflation device|DRUG: Neuromuscular blockade reversal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Comparative Effects Of Spencer and Reverse Distraction Technique In Patients With Adhesive Capsulitis
Status: RECRUITING
Conditions: Spencer and Reverse Distraction Technique
Interventions: PROCEDURE: Spencer technique|PROCEDURE: reverse distraction technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Adjunctive Corticosteroids for Tuberculous Meningitis in HIV-infected Adults (The ACT HIV Trial)
Status: COMPLETED
Conditions: Tuberculosis|Tuberculous Meningitis|Drug-Induced Liver Injury|HIV|IRIS
Interventions: DRUG: Dexamethasone|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Cetuximab Plus Combination Chemotherapy in Treating Patients With Stage IV Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: BIOLOGICAL: cetuximab|DRUG: fluorouracil|DRUG: irinotecan hydrochloride|DRUG: leucovorin calcium
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Tolerance of Healthy Infants Fed Infant Formulas
Status: COMPLETED
Conditions: Gastrointestinal Tolerance
Interventions: OTHER: Phase 1- Arm 1 Infant Formula|OTHER: Phase 2- Arm 2 Infant Formula|OTHER: Phase 2- Arm 3 Infant Formula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Acthar Gel for Chronic Pulmonary Sarcoidosis (ACPS)
Status: UNKNOWN
Conditions: Sarcoidosis|Pulmonary Sarcoidosis
Interventions: DRUG: Acthar gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Safety and Efficacy Study of E10030 (Anti-PDGF Pegylated Aptamer) Plus Lucentis for Neovascular Age-Related Macular Degeneration
Status: COMPLETED
Conditions: Age-Related Macular Degeneration
Interventions: DRUG: E10030 plus Lucentis|DRUG: Lucentis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of the Extracorporeal Liver Assist Device (ELAD) in Acute on Chronic Hepatitis
Status: COMPLETED
Conditions: Acute On Chronic Hepatitis
Interventions: BIOLOGICAL: ELAD plus standard of care treatment|OTHER: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CLDN6/GPC3/Mesothelin/AXL-CAR-NK Cell Therapy for Advanced Solid Tumors
Status: RECRUITING
Conditions: Stage IV Ovarian Cancer|Testis Cancer, Refractory|Endometrial Cancer Recurrent|CAR NK
Interventions: BIOLOGICAL: Claudin6, GPC3, Mesothelin, or AXL targeting CAR-NK cells
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Effectiveness and Safety of Topiramate Compared With a Standard Therapy in Patients Newly Diagnosed With Epilepsy
Status: COMPLETED
Conditions: Epilepsy|Seizures
Interventions: DRUG: Topiramate; Carbamazepine; Valproate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: The Safety and Efficacy of Clindamycin and Primaquine in the Treatment of Mild - Moderate Pneumocystis Carinii Pneumonia in Patients With AIDS
Status: COMPLETED
Conditions: Pneumonia, Pneumocystis Carinii|HIV Infections
Interventions: DRUG: Primaquine|DRUG: Clindamycin
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of Fundamental Modification of the Gut Microbiota in the Treatment of Refractory Crohn's Disease
Status: COMPLETED
Conditions: Crohn Disease
Interventions: DRUG: Vancomycin|DRUG: Neomycin|DRUG: Ciprofloxacin|DRUG: Polyethylene Glycol 3350|DRUG: Fluconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT