pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Safety and Efficacy of Enteral Feeding Tube Stoma Site Accessory
Status: ACTIVE_NOT_RECRUITING
Conditions: Feeding Tube Complication
Interventions: DEVICE: Placement of stoma site enteral feeding tube accessory
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intracorporeal Versus Extracorporeal Mechanical Anastomosis in Laparoscopic Right Colectomy
Status: UNKNOWN
Conditions: Neoplastic or Benign Disease of Right Colon|Elective Laparoscopic Surgery
Interventions: PROCEDURE: Laparoscopic right colectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Immune Response of One-Dose of Candidate H1N1 Influenza Vaccine GSK2340274A in Adults
Status: WITHDRAWN
Conditions: Influenza
Interventions: BIOLOGICAL: GSK Biologicals' investigational H1N1 Influenza Vaccine - GSK2340274A
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Randomized Controlled Trial of Leg Length Discrepancy Techniques
Status: RECRUITING
Conditions: Leg Length Discrepancy
Interventions: DEVICE: Tantalum Beads & Injector|PROCEDURE: Percutaneous Drill Epiphysiodesis|PROCEDURE: Percutaneous Screw Epiphysiodesis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating Vardenafil Compared to Placebo in Subjects With Erectile Dysfunction (ED) and Dyslipidemia
Status: COMPLETED
Conditions: Erectile Dysfunction
Interventions: DRUG: LEVITRA (vardenafil)|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: MIBG Scintigraphy as a Tool for Selecting Patients Requiring Implantable Cardioverter Defibrillator (ICD)
Status: UNKNOWN
Conditions: Heart Failure|Sudden Death
Interventions: RADIATION: MIBG for diagnostic purpose
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparison of Immediate and Delayed Adjuvant Chemotherapy in Treating Patients Who Have Undergone a Radical Cystectomy for Stage III or Stage IV Transitional Cell Carcinoma of the Bladder Urothelium
Status: COMPLETED
Conditions: Stage III Bladder Cancer|Stage IV Bladder Cancer|Transitional Cell Carcinoma of the Bladder
Interventions: DRUG: doxorubicin hydrochloride|DRUG: gemcitabine hydrochloride|DRUG: vinblastine sulfate|DRUG: methotrexate|DRUG: cisplatin|BIOLOGICAL: filgrastim
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Repetitive Transcranial Magnetic Stimulation (rTMS) for Obsessive-Compulsive Disorder (OCD)
Status: TERMINATED
Conditions: Obsessive-Compulsive Disorder
Interventions: DEVICE: Repetitive transcranial magnetic stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Phase II Study of Rituximab Combined With CHOP in T-cell Angio-immunoblastic Lymphoma
Status: COMPLETED
Conditions: Untreated T-cell Angioimmunoblastic Lymphoma
Interventions: DRUG: Rituximab|DRUG: Prednisone|DRUG: Doxorubicine|DRUG: Cyclophosphamide|DRUG: Vincristine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Utility of Selected Circulating Tumor DNA Assays in Patients With Advanced Malignancy
Status: RECRUITING
Conditions: Metastatic Colorectal Cancer|Pancreas Adenocarcinoma|Cholangiocarcinoma
Interventions: DIAGNOSTIC_TEST: Multiplex PCR-test for circulating tumor DNA
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase 1 Study To Evaluate The Safety And Tolerability Of Different Doses Of PF-03526299 In Healthy Adult Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: PF-03526299|DRUG: PF-03526299
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Vocal Cord vs Whole Laryngeal Radiotherapy for T1aN0 Glottic Cancer
Status: RECRUITING
Conditions: Larynx Cancer Stage I|Glottic Carcinoma
Interventions: RADIATION: Hypofractionated single vocal cord irradiation|RADIATION: Whole laryngeal radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: STRONG - Study of AGN1 LOEP for the Treatment of the Contralateral Femur After Fragility Fracture
Status: COMPLETED
Conditions: Hip Fractures|Osteoporosis, Postmenopausal
Interventions: DEVICE: AGN1 Femoral Local Osteo-Enhancement Procedure Kit
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nivolumab in Recurrent and/or Metastatic SCCHN
Status: COMPLETED
Conditions: Recurrent and/or Metastatic Platinum-refractory SCCHN
Interventions: DRUG: Nivolumab Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I Study of Oral Topotecan as a Radiosensitizing Agent in Patients With Rectal Carcinoma
Status: COMPLETED
Conditions: Rectal Neoplasms
Interventions: DRUG: topotecan|PROCEDURE: radiation|PROCEDURE: surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cannabidiol for Reducing Cigarette Use
Status: NOT_YET_RECRUITING
Conditions: Tobacco Use Disorder|Tobacco Smoking|Tobacco Dependence
Interventions: DRUG: Cannabidiol (CBD) 400 mg or 800 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vitamin D Supplementations as Adjunct to Anti-Tuberculosis Drugs in Mongolia
Status: COMPLETED
Conditions: Vitamin D Supplements|Tuberculosis|Sputum|Cytokines|Immunity
Interventions: DIETARY_SUPPLEMENT: Vitamin D
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ph II Study of Pembrolizumab & Eribulin in Patients With HR+/HER2- MBC Previously Treated With Anthracyclines & Taxanes
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Pembrolizumab|DRUG: Eribulin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dimensional Changes in Single Crowns Supported by Short Transmucosal Implants With Diverging or Converging Neck Profiles in the Esthetic Zone
Status: RECRUITING
Conditions: Edentulous Alveolar Ridge
Interventions: PROCEDURE: Dental implants placement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized Controlled Trial to Evaluate the Effectiveness of Electromyography (EMG)-Biofeedback in Patients With Fibromyalgia
Status: COMPLETED
Conditions: Fibromyalgia
Interventions: OTHER: EMG-Biofeedback and Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Oral Morphine Gel in Oral Mucositis Induced by Chemotherapy in Children and Young Adults
Status: UNKNOWN
Conditions: Cancer
Interventions: DRUG: morphine gel|DRUG: placebo gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Monoclonal Antibody Therapy and Vaccine Therapy in Treating Patients With Resected Stage III or Stage IV Melanoma
Status: COMPLETED
Conditions: Intraocular Melanoma|Melanoma (Skin)
Interventions: BIOLOGICAL: ipilimumab|BIOLOGICAL: Tyrosinase/gp100/MART-1 Peptides
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Donepezil HCl 23 mg in Patients With Moderate to Severe Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: Donepezil HCL
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Centration of Intraocular Lens With Two Settings for Capsulorhexis With Femtosecond Laser
Status: COMPLETED
Conditions: Capsulorhexis
Interventions: PROCEDURE: capsulorhexis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: SBRT Plus Pembrolizumab and Trametinib for Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DEVICE: Cyberknife plus Pembrolizumab and Trametinib|DEVICE: Cyberknife plus Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Validity of Using Connected Soles In Measuring Steps Number In the Older Subject, Hospitalized in Follow-up and Rehabilitative Care and Achieve Its Rehabilitation Objectives
Status: WITHDRAWN
Conditions: Patient Recovering Maximum Walking Capacity, Over 10 Meters
Interventions: DEVICE: Feetme Connected Soles
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Sulfureous Water Therapy in Viral Respiratory Diseases
Status: COMPLETED
Conditions: Long-COVID|Post COVID-19 Condition|Chronic COVID-19 Syndrome|Post Acute Sequelae of COVID-19
Interventions: OTHER: Inhalation of Sulfurous Thermal Water|OTHER: Inhalation of Sterile Distilled non-pyrogenic Water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Observational Study to Collect Data on How Aflibercept (Eylea) Given Using a Paediatric Dosing Device is Used in Preterm Babies With Retinopathy of Prematurity in the United Kingdom (UK)
Status: RECRUITING
Conditions: Retinopathy of Prematurity|Preterm Infants
Interventions: DRUG: Aflibercept (Eylea)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Japan-Working Groups of Acute Myocardial Infarction for the Reduction of Necrotic Damage by ANP
Status: COMPLETED
Conditions: Acute Myocardial Infarction
Interventions: DRUG: ANP(hANP)|DRUG: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Strength and Muscle Related Outcomes for Nutrition and Lung Function in CF
Status: RECRUITING
Conditions: Cystic Fibrosis
Interventions: DIAGNOSTIC_TEST: BMI and lean mass index from DXA|DIAGNOSTIC_TEST: Anthropometric Measurements|DIAGNOSTIC_TEST: Hand-grip strength|DIAGNOSTIC_TEST: Six-minute walk Test|DIAGNOSTIC_TEST: Sit-to-Stand Test|DIAGNOSTIC_TEST: Short physical performance battery (SPPB)|DIAGNOSTIC_TEST: BIA Sub-study|DIAGNOSTIC_TEST: Accelerometry to assess physical activity|OTHER: Gastrointestinal (GI) and nutrition questionnaires:|OTHER: Psychosocial questionnaire: PHQ-8|OTHER: Psychosocial questionnaire: GAD-7|OTHER: Psychosocial questionnaire: The Treatment Self-Regulation Questionnaire (TSRQ)|OTHER: Psychosocial questionnaire: CF Fatalism Scale|OTHER: Psychosocial questionnaire: Body Esteem Scale for Adolescents and Adults (BESAA)|OTHER: 12-month Questionnaire|OTHER: Oral glucose tolerance testing (OGTT)|DEVICE: Continuous glucose monitoring (CGM)|DIAGNOSTIC_TEST: Chest CT scans (When available within the past 6 months in medical records)|DIAGNOSTIC_TEST: Hologic Dual X-Ray Absorptiometry (DXA)|DIAGNOSTIC_TEST: Ultrasound Sub-study of assessment of appendage muscles using ultrasound|DIAGNOSTIC_TEST: Psychosocial questionnaire: Hunger Vital Sign questionnaire|OTHER: Respiratory symptom questionnaire: CRISS|DIAGNOSTIC_TEST: Spirometry|OTHER: Psychosocial questionnaire: Additional Health Questionnaire
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Interventional Effects on Myocardial Revascularization Post-surgical Patients
Status: COMPLETED
Conditions: Myocardial Revascularization
Interventions: OTHER: Conventional Therapy|OTHER: Cycle ergometer combine with CPAP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Detergents in the Pathogenesis of Eosinophilic Esophagitis
Status: ACTIVE_NOT_RECRUITING
Conditions: Eosinophilic Esophagitis
Interventions: DIAGNOSTIC_TEST: Esophageal String Test (EST)|OTHER: Colgate|DIAGNOSTIC_TEST: High Resolution Esophageal Manometry (HREM)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Combination Chemotherapy Followed by Melphalan and Peripheral Stem Cell Transplantation in Treating Children With Newly Diagnosed Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Leukemia
Interventions: BIOLOGICAL: filgrastim|DRUG: asparaginase|DRUG: cytarabine|DRUG: daunorubicin hydrochloride|DRUG: melphalan|DRUG: thioguanine|PROCEDURE: peripheral blood stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Growth Hormone Deficiency in Mild Traumatic Brain Injury
Status: NOT_YET_RECRUITING
Conditions: Growth Hormone Treatment|Growth Hormone Deficiency|Concussion, Mild|Concussion Post Syndrome
Interventions: DRUG: Growth Hormone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Effect on Metabolism, Food Intake and Preferences of a Knockout Gene Variant Involved in Carbohydrate Metabolism
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Metabolic Disease|Sucrose Intolerance Congenital|Sucrase Isomaltase Deficiency
Interventions: OTHER: Cross-over study
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: 0.3% Sodium Hyaluronate Eye Drop to Prevent Recurrent Corneal Epithelium Exfoliation
Status: UNKNOWN
Conditions: Corneal Epithelium Exfoliation
Interventions: DRUG: 0.3% Sodium Hyaluronate Eye Drop
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Diagnostic Immunization With Rabies Vaccine in Patients With PID
Status: UNKNOWN
Conditions: Primary Immunodeficiency
Interventions: BIOLOGICAL: Verorab® (PVRV; Purified Vero Cell Vaccine)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Bortezomib, Paclitaxel, Carboplatin and Radiation Therapy for Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Recurrent Non-small Cell Lung Cancer|Stage IIIA Non-small Cell Lung Cancer|Stage IIIB Non-small Cell Lung Cancer
Interventions: RADIATION: 3-dimensional conformal radiation therapy|DRUG: bortezomib|DRUG: paclitaxel|DRUG: carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Arginine/Omega-3 Fatty Acids/Nucleotides Nutritional Supplement in Treating Patients With Stage III or Stage IV Head and Neck Cancer Undergoing Chemotherapy and Radiation Therapy
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: DIETARY_SUPPLEMENT: arginine/omega-3 fatty acids/nucleotides oral supplement|DRUG: cisplatin|PROCEDURE: adjuvant therapy|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Ledipasvir/Sofosbuvir Fixed-Dose Combination for 12 Weeks in Subjects With Chronic Genotype 1 or 4 HCV and HIV-1 Co-infection
Status: COMPLETED
Conditions: Hepatitis C Virus|HIV
Interventions: DRUG: LDV/SOF|DRUG: RBV
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ketorolac in Palatoplasty
Status: RECRUITING
Conditions: Cleft Lip and Palate
Interventions: DRUG: Ketorolac|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Genolimzumab (GB226) in Combination With Fruquintinib
Status: UNKNOWN
Conditions: Metastatic Non-small Cell Lung Cancer
Interventions: DRUG: GB226|DRUG: Fruquintinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing the Pharmacokinetics and Palatability of Two Candidate Pediatric Powder-for-Oral-Suspension Formulations of Maribavir to the Current Maribavir Tablet Formulation Administered in Healthy Adult Participants
Status: TERMINATED
Conditions: Healthy Volunteers
Interventions: DRUG: Maribavir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Patient Perceptions of the Relational Empathy of Healthcare Practitioners From the Department of Emergency Medicine During the COVID-19 Pandemic
Status: ACTIVE_NOT_RECRUITING
Conditions: COVID-19 Infection|Hematopoietic and Lymphoid Cell Neoplasm|Malignant Solid Neoplasm
Interventions: OTHER: Best Practice|PROCEDURE: Discussion|OTHER: Questionnaire Administration
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Brentuximab Vedotin Trial for Patients Who Have Previously Participated in a Brentuximab Vedotin Study
Status: COMPLETED
Conditions: Disease, Hodgkin|Lymphoma, Large-Cell, Anaplastic|Lymphoma, Non-Hodgkin
Interventions: DRUG: brentuximab vedotin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Detection Of Atrial Fibrillation In Patients With Transient Ischemic Attack
Status: COMPLETED
Conditions: Transient Ischemic Attack|Atrial Fibrillation
Interventions: DEVICE: Implantable loop-recorder
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: AZD2171 to Treat Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: PROCEDURE: Magnetic Resonance Imaging (DCE-MRI)|DRUG: AZD2171|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: e-Health Intervention (Day-by-Day) for the Management of Fear of Progression in Women With Stage III or IV Gynecologic Cancer: A Pilot Study
Status: RECRUITING
Conditions: Malignant Female Reproductive System Neoplasm|Stage III Cervical Cancer AJCC v8|Stage III Ovarian Cancer AJCC v8|Stage III Uterine Corpus Cancer AJCC v8|Stage III Vaginal Cancer AJCC v8|Stage III Vulvar Cancer AJCC v8|Stage IV Cervical Cancer AJCC v8|Stage IV Ovarian Cancer AJCC v8|Stage IV Uterine Corpus Cancer AJCC v8|Stage IV Vaginal Cancer AJCC v8|Stage IV Vulvar Cancer AJCC v8
Interventions: PROCEDURE: Discussion|OTHER: Informational Intervention|OTHER: Media Intervention|OTHER: Questionnaire Administration|BEHAVIORAL: Telephone-Based Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of One Morphine Sulfate Sustained-Release 200mg Capsule With Two 100 mg KADIAN Capsules Under Fed Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: morphine sulfate sustained-release capsules|DRUG: KADIAN
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Phase I Multicenter Clinical Trial to Evaluate the Safety and Immunogenicity of Vaccinia Derived HIV-1 Recombinant Envelope Glycoprotein (gp160) of Human Immunodeficiency Virus: Evaluation of a 200-mcg Dose
Status: COMPLETED
Conditions: HIV Infections
Interventions: BIOLOGICAL: gp160 Vaccine (Immuno-AG)
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Abscopal Effect From the Low-dose Radiotherapy in Polymetastatic Cancer Patients Receiving Stereotactic Radiotherapy
Status: RECRUITING
Conditions: Neoplasms|Secondary Malignant Neoplasm
Interventions: RADIATION: SBRT + LDRT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Two Inhalation Methods Using a Pressurized Metered Dose Inhaler With Valved Holding Chamber to Assess Improvement in Lung Function After SABA Administration in Bronchial Asthma
Status: COMPLETED
Conditions: Bronchial Asthma
Interventions: PROCEDURE: Single Inhalation technique|PROCEDURE: Tidal inhalation technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Spot Drug-Eluting Stenting for Long Coronary Stenoses
Status: COMPLETED
Conditions: Angioplasty
Interventions: DEVICE: Drug-eluting stents (Cypher and Taxus)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Analysis of the Prevalence and Characteristics of Concomitant Sleep and Headache Disorders, and the Efficacy of CPAP Treatment for Headache Among Those Patients Diagnosed With Obstructive Sleep Apnea
Status: UNKNOWN
Conditions: Headache Disorder|Sleep Disorder|Obstructive Sleep Apnea
Interventions: DEVICE: Continuous positive airway pressure (CPAP)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Long-term Study to Assess the Safety and Efficacy of Efgartigimod in Adult Patients With Primary Immune Thrombocytopenia (ITP).
Status: ACTIVE_NOT_RECRUITING
Conditions: Primary Immune Thrombocytopenia
Interventions: BIOLOGICAL: efgartigimod
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Digitally Delivered and Group-based CBT-I in Pregnant Women With Comorbid Insomnia and Depression
Status: RECRUITING
Conditions: Pregnancy Related|Depression|Insomnia
Interventions: BEHAVIORAL: Group CBT-I|BEHAVIORAL: App-based CBT-I|OTHER: Health related psychoeducation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of the Safety and Efficacy of Sulfasalazine in Pulmonary Arterial Hypertension
Status: UNKNOWN
Conditions: Pulmonary Arterial Hypertension
Interventions: DRUG: Sulfasalazine|DRUG: Ambrisentan|DRUG: Sulfasalazine's placebo|DRUG: Ambrisentan's placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Prophylactic Low-molecular Weight Heparin Dosing on Clotting Parameters Following Cesarean Delivery
Status: COMPLETED
Conditions: Thromboembolism|Postpartum DVT|Thrombosis
Interventions: DRUG: Enoxaparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Dose-escalation Study of IMC-001 in Subject With Metastatic or Locally-advanced Solid Tumors
Status: COMPLETED
Conditions: Solid Tumor|Metastasis|Locally Advanced
Interventions: DRUG: IMC-001
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Bone Modeling Effects of Combined Anabolic/Antiresorptive Administration
Status: COMPLETED
Conditions: Postmenopausal Osteoporosis
Interventions: DRUG: Teriparatide|DRUG: Denosumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Postbiotics Supplementation, Gut Microbiota Composition, and Exercise-induced Inflammation
Status: RECRUITING
Conditions: Postbiotics Supplementation
Interventions: DIETARY_SUPPLEMENT: Postbiotics supplementation|DIETARY_SUPPLEMENT: Placebo supplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Bilateral Transversus Abdominis Plane Block Versus Atracurium During Laparoscopic Gynecology Procedures.
Status: COMPLETED
Conditions: Neuromuscular Blockade|Regional Anesthesia
Interventions: PROCEDURE: Bilateral ultrasound guided TAP bloc|DRUG: Neuromuscular blockade agent: Atracurium 01mg/kg per bolus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ruxolitinib for Newly Diagnosed Bronchiolitis Obliterans Syndrome
Status: RECRUITING
Conditions: Bronchiolitis Obliterans Syndrome|Hematologic Malignancy
Interventions: DRUG: Ruxolitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study for An Artificial Disc Replacement to Treat Chronic Low Back Pain
Status: UNKNOWN
Conditions: Degenerative Disc Disease|Chronic Low-back Pain
Interventions: DEVICE: PerQdisc® Nucleus Replacement Device.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assess the Safety & Reactogenicity of DTPa-IPV/Hib Vaccine Administered at 3, 4, 5 & 18 Mths of Age, in Healthy Infants
Status: COMPLETED
Conditions: Diphtheria|Tetanus|Poliomyelitis|Acellular Pertussis|Haemophilus Influenzae Type b|Diphtheria-Tetanus-aPertussis-Poliomyelitis Vaccines
Interventions: BIOLOGICAL: GSK Biologicals' combined DTPa-IPV/Hib vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Rosiglitazone Anti-inflammatory Effect With FDG-PET Imaging
Status: COMPLETED
Conditions: Lung Inflammation
Interventions: DRUG: Zileuton|DRUG: Pioglitazone placebo|DRUG: Zileuton placebo|DRUG: Pioglitazone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Dynamic Preload Dependence Indices in Laparoscopic Surgery
Status: COMPLETED
Conditions: Laparoscopic Surgery
Interventions: PROCEDURE: Study of preload dependence indices after volume expansion in laparoscopy with Saldinger technique.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: G-CSF+DAC+BUCY vs G-CSF+DAC+BF Conditioning Regimen for RAEB-1,REAB-2 and AML Secondary to MDS Undergoing Allo-HSCT
Status: UNKNOWN
Conditions: Myelodysplastic Syndrome|Allogeneic Hematopoietic Stem Cell Transplantation|Conditioning
Interventions: DRUG: Granulocyte Colony-Stimulating Factor(G-CSF)|DRUG: Decitabine (DAC)|DRUG: Busulfan (BU)|DRUG: Cyclophosphamide (CY)|DRUG: Fludarabine (FLU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of LY3532226 in Participants With Obesity
Status: NOT_YET_RECRUITING
Conditions: Obesity
Interventions: DRUG: LY3532226|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Single Dose Escalation Study of TR02 (Sustained Lipid Inhalation Technology [SLIT™] Amikacin) in Participants With Cystic Fibrosis (CF) Having Chronic Infections of Pseudomonas Aeruginosa
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: SLIT™ Amikacin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation Phenobarbital as Adjunctive Therapy in Participants With Partial Onset Seizures
Status: COMPLETED
Conditions: Epilepsy
Interventions: DRUG: Phenobarbital|DRUG: Placebo tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Success of Internal Jugular Vein Catheterization
Status: COMPLETED
Conditions: Ultrasound|Catheterization|Volume Status
Interventions: PROCEDURE: Internal Jugular Vein Catheterization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Autologous T Cells Expressing MET scFv CAR (RNA CART-cMET)
Status: TERMINATED
Conditions: Malignant Melanoma|Breast Cancer
Interventions: BIOLOGICAL: T cells modified with RNA anti -cMET CAR
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Safety of Quetiapine XR in Patients With Schizophrenia Switched From Other Antipsychotics
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Administration of quetiapine XR
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Clinical Efficacy and Safety of Subcutaneously Administered C1-esterase Inhibitor in the Prevention of Hereditary Angioedema
Status: COMPLETED
Conditions: Hereditary Angioedema Types I and II
Interventions: BIOLOGICAL: Low-volume C1-esterase inhibitor|BIOLOGICAL: Higher-volume C1-esterase inhibitor|BIOLOGICAL: Low-volume placebo|BIOLOGICAL: Higher-volume placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of Lateral and Medial Approaches to Costoclavicular Brachial Plexus Block in Pediatrics
Status: COMPLETED
Conditions: Anesthesia, Local|Postoperative Pain
Interventions: DRUG: Bupivacaine 0.25% Injectable Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Effect of an L-carnitine-containing Peritoneal Dialysis (PD) Solution on Insulin Sensitivity in Patients on Continuous Ambulatory Peritoneal Dialysis (CAPD)
Status: COMPLETED
Conditions: End Stage Renal Disease|Insulin Resistance
Interventions: DRUG: PD solution containing glucose|DRUG: PD solution containing glucose and L-carnitine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of Applying Art Therapy on Social Interaction, Self-esteem and Well-Being for Elderly Residents in Long-Term Care Institutions
Status: UNKNOWN
Conditions: Long-Term Care|Aged
Interventions: OTHER: Art therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Efficacy of Intravenous Immunoglobulin IgPro10 in Patients With Primary Immunodeficiencies (PID)
Status: COMPLETED
Conditions: Agammaglobulinemia|IgG Deficiency|Common Variable Immunodeficiency
Interventions: DRUG: Immunoglobulins Intravenous (Human)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Postconditioning in the Treatment of Acute ST-segment Elevation Myocardial Infarction
Status: COMPLETED
Conditions: ST-segment Myocardial Infarction
Interventions: PROCEDURE: Standard primary PCI|PROCEDURE: Mechanical postconditioning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Impact of Different Breakfast Meals on Food Choices, Eating Behaviors and Brain Activation
Status: COMPLETED
Conditions: Regulation, Appetite|Eating Behavior|Cognition
Interventions: OTHER: Breakfast consumption|OTHER: Blood tests|OTHER: Food choices and energy intakes assessments|OTHER: Attention tests|OTHER: fRMI tests
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Assessing the Role of a Fermented Soy Extract in Inflammation and the Human Microbiome
Status: COMPLETED
Conditions: Obesity
Interventions: OTHER: Food: (Q-Can Plus fermented soybean beverage)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of Effect of Muscle Energy Technique vs PNF in Individuals With Hamstring Shortness
Status: UNKNOWN
Conditions: Hamstring Shortness
Interventions: DIAGNOSTIC_TEST: Muscle Energy Technique|DIAGNOSTIC_TEST: Proprioception neuromuscular facilitation (PNF)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Effectiveness of ThOracic Epidural and Paravertebral Blockade In Reducing Chronic Post- Thoracotomy Pain: 2
Status: UNKNOWN
Conditions: Anesthesia|Thoracic Diseases
Interventions: PROCEDURE: Paravertebral blockade|PROCEDURE: Thoracic epidural block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose-Ranging Study to Evaluate a 25-Valent Pneumococcal Conjugate Vaccine
Status: ACTIVE_NOT_RECRUITING
Conditions: Pneumococcal Vaccines
Interventions: BIOLOGICAL: IVT PCV-25 Formulation A|BIOLOGICAL: IVT PCV-25 Formulation B|BIOLOGICAL: IVT PCV-25 Formulation C|BIOLOGICAL: PCV 20
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Regeneration of Immature Teeth. Case Series
Status: ACTIVE_NOT_RECRUITING
Conditions: Revascularization
Interventions: PROCEDURE: Triple paste and induced bleeding|DRUG: Triple Paste metronidazole, ciprofloxacin and minocycline mixed with sterile glycol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of HS-10504 in Patients With Advanced or Metastatic Non-Small-Cell Lung Cancer(NSCLC)
Status: NOT_YET_RECRUITING
Conditions: Locally Advanced or Metastatic NSCLC
Interventions: DRUG: HS-10504
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: E-B-FAHF-2, Multi OIT and Xolair for Food Allergy
Status: COMPLETED
Conditions: Food Allergy
Interventions: DRUG: Drug: Chinese Herbal Medication|DRUG: Drug: Placebo|DRUG: Drug: Omalizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Muscle Stimulation for Physical Function During Stem Cell Transplant
Status: RECRUITING
Conditions: Autologous Hematopoietic Stem Cell Transplant
Interventions: DEVICE: RS-4i Plus Sequential Stimulator (RS Medical, Vancouver, WA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Targeted Elimination Diet in EoE Patients Following Identification of Trigger Nutrients Using Confocal Laser Endomicroscopy
Status: RECRUITING
Conditions: Eosinophilic Esophagitis
Interventions: OTHER: personalized exclusion diet based on CLE|OTHER: empiric exclusion diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy, Safety, and Tolerability of Ancrod in Patients With Sudden Hearing Loss
Status: COMPLETED
Conditions: Hearing Loss|Deafness|Hearing Loss, Sensorineural|Hearing Disorders|Ear Diseases
Interventions: DRUG: Ancrod|DRUG: Saline solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acid Tranexamic Effectiveness in Reducing the Intraoperative Bleeding in Palatoplasty
Status: COMPLETED
Conditions: Cleft Palate|Hemorrhage
Interventions: DRUG: Tranexamic Acid|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: CMR to Assess Fibrosis in Cardiomyopathy Using Eplerenone
Status: COMPLETED
Conditions: Cardiomyopathy
Interventions: DRUG: Eplerenone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Trial to Evaluate the Safety and the Immunogenicity of GSK Biologicals' Influenza Vaccine GSK2186877A in Healthy Children
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Influenza vaccine GSK2186877A formulation 1|BIOLOGICAL: Influenza vaccine GSK2186877A formulation 2|BIOLOGICAL: Fluarix
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Implementation and Evaluation of a Rare Disease Algorithm to Identify Persons at Risk of Gaucher Disease Using Data From Electronic Health Records (EHRs) in the United States (Project Searchlight)
Status: RECRUITING
Conditions: Gaucher Disease
Interventions: PROCEDURE: Investigational procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Comparative Evaluation of Pulpotomized Primary Molars With Mineral Trioxide Aggregate and New Endodonthic Cement
Status: UNKNOWN
Conditions: Pulpotomy Treatment
Interventions: PROCEDURE: pulpotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Visualization of Anti-angiogenic Effects With Perfusion Computed Tomography (CTP)
Status: TERMINATED
Conditions: Metastatic Colorectal Cancer
Interventions: DEVICE: Computed tomography X-ray system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Sleeve Gastrectomy Versus One-anastomosis Gastric Bypass: Randomized Trial
Status: UNKNOWN
Conditions: Morbid Obesity
Interventions: PROCEDURE: sleeve gastrectomy|PROCEDURE: one anastomosis gastric bypass
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Bortezomib in Combination With Cyclophosphamide and Rituximab
Status: COMPLETED
Conditions: Mantle Cell Lymphoma|Lymphoma
Interventions: DRUG: Bortezomib|DRUG: Rituximab|DRUG: Cyclophosphamide|DRUG: Mesna|DRUG: G-CSF
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Standard Genetic Counseling With or Without a Decision Guide in Improving Communication Between Mothers Undergoing BRCA1/2 Testing and Their Minor-Age Children
Status: COMPLETED
Conditions: Breast Cancer|Hereditary Breast/Ovarian Cancer (brca1, brca2)
Interventions: OTHER: counseling intervention|OTHER: educational intervention|OTHER: survey administration|BEHAVIORAL: psychosocial assessment and care|BEHAVIORAL: supportive care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Safety and Efficacy of Albiglutide in Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: BIOLOGICAL: albiglutide|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of RO4995819 in Combination With Citalopram in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: RO4995819|DRUG: citalopram|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Efficacy of Tinoridine in Treating Pain and Inflammation in Adults
Status: COMPLETED
Conditions: Pain|Inflammation
Interventions: DRUG: Tinoridine HCl|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vaccine Therapy in Healthy Volunteers With or Without Previous Exposure to Cytomegalovirus
Status: COMPLETED
Conditions: Cytomegalovirus Infection|Healthy, no Evidence of Disease
Interventions: BIOLOGICAL: multi-CMV epitope modified vaccinia Ankara vaccine|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of the Safety and Immunogenicity of SII Vaccine Constructs Based on the SARS-CoV-2 (COVID-19) Variant in Adults
Status: WITHDRAWN
Conditions: Covid19
Interventions: BIOLOGICAL: SII B.1.351|BIOLOGICAL: SII B.1.351|BIOLOGICAL: SII Bivalent|BIOLOGICAL: SII Bivalent|BIOLOGICAL: SII B.1.617.2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Ondissolve in the Prophylaxis/Rescue of Radiation Induced Nausea and Vomiting
Status: COMPLETED
Conditions: Nausea|Vomiting
Interventions: DRUG: Ondansetron
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effect of Cold Vapor on Intubation-Related Symptoms and Comfort in the Early Postoperative Period
Status: UNKNOWN
Conditions: Intubation Complication|Cold|Sore Throat|Cough|Hoarseness|Dysphagia
Interventions: OTHER: Cold vapor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Continuous Passive Motion Versus Heterotopic Ossification
Status: RECRUITING
Conditions: Traumatic Brain Injury|Spinal Cord Injuries|Stroke
Interventions: DEVICE: Continuous Passive Motion (CPM)|OTHER: Conventional physiotherapy (PT)|DRUG: Zoledronic Acid Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Home-based tDCS for Prevention of Suicidal Ideation
Status: COMPLETED
Conditions: Suicidal Ideation
Interventions: DEVICE: Home-based transcranial direct current stimulation (tDCS)|DEVICE: Sham home-based transcranial direct current stimulation (tDCS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: The Effect of Very Low Calorie Diet With and Without Exercise on Muscle Synthesis in Middle-aged Overweight Male.
Status: UNKNOWN
Conditions: Overweight and Obesity
Interventions: DIETARY_SUPPLEMENT: Very low calorie diet (VLCD)|OTHER: High intensity interval training (HIIT)|OTHER: Resistance exercise training (RET)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Use of Topical Budesonide in the Treatment of Eosinophilic Esophagitis
Status: COMPLETED
Conditions: Eosinophilic Esophagitis
Interventions: DRUG: Budesonide plus Prevacid|DRUG: placebo plus Prevacid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Differences in Pharmadynamics, Pharmacokinetics, and Safety Between Ciprofol and Propofol
Status: COMPLETED
Conditions: Anesthesia
Interventions: DRUG: Ciprofol|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tranexamic Acid in Patients for Caesarian Delivery.
Status: COMPLETED
Conditions: Postpartum Hemorrhage|Cesarean Section Complications|Obstetric Anesthesia Problems
Interventions: DRUG: Tranexamic acid injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Dopamine Transporter Scintigraphy Imaging (DAT-Imaging) in Patients With Lewy Body Dementia
Status: COMPLETED
Conditions: Lewy Body Dementia|Non-DLB Dementia|Alzheimer's|Vascular Dementia
Interventions: DRUG: DatSCAN
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC