pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Follow-up Extension Study to Evaluate the Persistence of Immune Response to GSK Biologicals' HPV Vaccine in Healthy Chinese Female Subjects Who Received Three Doses of the Vaccine in the HPV-058 Study
Status: COMPLETED
Conditions: Cervical Intraepithelial Neoplasia
Interventions: PROCEDURE: Blood sampling for antibody determination
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Concurrent Trigger Sensitivity Adjustment And Diaphragmatic Facilitation On Weaning From Mechanical Ventilation
Status: COMPLETED
Conditions: Acute Respiratory Failure|Mechanically Ventilated Patients
Interventions: PROCEDURE: Manual diaphragmatic facilitation (PNF) technique|PROCEDURE: Trigger sensitivity adjustment on mechanical ventilation|PROCEDURE: concurrent trigger sensitivity adjustment and manual diaphragmatic facilitation (PNF) technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: An Open-Label Extension Study Assessing the Long-Term Efficacy and Safety of ALX-0061 in Subjects With Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: BIOLOGICAL: ALX-0061
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Research on a Novel Deep-learning Based System in Pancreatic Mass Diagnosis
Status: UNKNOWN
Conditions: Solid Pancreatic Masses
Interventions: PROCEDURE: artificial-EUS-FNA|PROCEDURE: AI-EUS-FNA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy Safety and Tolerability of Multiple Doses of Oshadi Icp (Oshadi Oral Insulin) in Patients With Type 1 Diabetes Mellitus - Phase II Clinical Study
Status: COMPLETED
Conditions: Diabetes Mellitus|Insulin-Dependent|Type 1
Interventions: DRUG: Oshadi Icp
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Living Conditions of Patients With Diffuse Large B-Cell Lymphoma or Follicular Lymphoma in the Côte d'Or Region
Status: COMPLETED
Conditions: Diffuse Large Cell Diffuse Lymphoma|Follicular Lymphoma
Interventions: OTHER: Questionnaires|OTHER: Collection of clinical data and treatments
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Cocktail Injection Improves Outcomes of FFR Guided PCI
Status: UNKNOWN
Conditions: Acute Coronary Syndromes
Interventions: DRUG: cocktail|DEVICE: FFR|DEVICE: QCA guided group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Amniotic Membrane Associated With Conjunctival Autograft Versus Conjunctival Autograft for Recurrent Pterygia
Status: UNKNOWN
Conditions: Recurrent Pterygia
Interventions: PROCEDURE: Conjunctival autograft versus conjunctival autograft treatment for recurrent pterygia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Health Responsibility and Family Planning ın Immigrant Women (Ahıska Turks).
Status: UNKNOWN
Conditions: Health, Subjective|Family Planning|Women|Nurse
Interventions: OTHER: Health Responsibility and Family Planning ın Immigrant Women (Ahıska Turks).|OTHER: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Effectiveness of ABT-378/Ritonavir Plus Lamivudine Plus Efavirenz Plus Tenofovir DF in HIV-Infected Patients
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Lopinavir/ritonavir|DRUG: Efavirenz|DRUG: Lamivudine|DRUG: Tenofovir DF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lutathera for the Treatment of Inoperable, Progressive Meningioma After External Beam Radiation Therapy
Status: RECRUITING
Conditions: Grade 1 Meningioma|Grade 2 Meningioma|Grade 3 Meningioma|Recurrent Meningioma|Unresectable Meningioma
Interventions: RADIATION: Gallium Ga 68-DOTATATE|DRUG: Lutetium Lu 177 Dotatate|PROCEDURE: Magnetic Resonance Imaging|PROCEDURE: Positron Emission Tomography|OTHER: Questionnaire Administration|PROCEDURE: Computed Tomography|PROCEDURE: Biospecimen Collection|PROCEDURE: Single Photon Emission Computed Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Solarplast® on Immunity in Active Smokers and Non-smokers
Status: COMPLETED
Conditions: Immunity|Smoking, Cigarette
Interventions: DIETARY_SUPPLEMENT: 100 mg Solarplast|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Drugs Brain and Behavior (DDP)
Status: COMPLETED
Conditions: Stimulant Use
Interventions: DRUG: Methamphetamine|DRUG: placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Cross-Over Study in Subjects With COPD, Evaluating Lung Function Response After Treatment With Once Daily Umeclidinium 62.5mcg, Vilanterol 25mcg, and Umeclidinium/Vilanterol 62.5/25mcg
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DEVICE: Umeclidinium/Vilanterol 62.5/25 mcg|DEVICE: Umeclidinium 62.5 mcg|DEVICE: Vilanterol 25 mcg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study for the Field-directed Treatment of Actinic Keratosis (AK) With Photodynamic Therapy (PDT)
Status: COMPLETED
Conditions: Actinic Keratosis
Interventions: DRUG: BF-200 ALA gel|DRUG: Placebo to BF-200 ALA gel|PROCEDURE: Photodynamic therapy with BF-RhodoLED
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prostate Cancer Patient Management With 18F-DCFPyL PET/CT
Status: ENROLLING_BY_INVITATION
Conditions: Prostate Cancer
Interventions: DIAGNOSTIC_TEST: 18F-DCFPyL PET/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Gut Microbiota Transplantation in Systemic Sclerosis
Status: COMPLETED
Conditions: Scleroderma, Systemic
Interventions: BIOLOGICAL: Anaerobically Cultivated Human Intestinal Microbiota|BIOLOGICAL: Anaerobically Cultivated medium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Virologic and Immunologic Responses to Raltegravir and Dolutegravir in the Gastrointestinal Tract of HIV-Positive Adults
Status: COMPLETED
Conditions: Human Immunodeficiency Virus
Interventions: DRUG: Raltegravir|DRUG: Dolutegravir|PROCEDURE: Colonoscopy with biopsy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy Trial Healthy Dads, Healthy Kids for Hispanic Fathers and Children
Status: RECRUITING
Conditions: Obesity|Obesity, Childhood|Physical Activity|Dietary Intake
Interventions: BEHAVIORAL: Healthy Dads Healthy Kids|OTHER: Standard of care control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 3 Clinical Trial to Evaluate the Efficacy and Safety of [18F]NAV4694 PET for Detection of Cerebral Beta-Amyloid When Compared With Postmortem Histopathology
Status: UNKNOWN
Conditions: Dementia|Alzheimer's Disease
Interventions: DRUG: [18F]NAV4694
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Antiseptic Efficacy and Tolerability of Lavasept® 0.04% on Acute Traumatic Wounds
Status: COMPLETED
Conditions: Wounds
Interventions: DRUG: Lavasept 0.04%|OTHER: Ringer's Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pedometer Intervention and Health Effects for Sedentary Colorectal Cancer Patients During Adjuvant Chemotherapy
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: BEHAVIORAL: Pedometer intervention|BEHAVIORAL: Pedometer + hospital based intervention|DEVICE: Omron Walking Style pro. 20
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: The Effect of Nasal Carbon Dioxide (CO2) Used As-Needed in the Symptomatic Treatment of Seasonal Allergic Rhinitis
Status: COMPLETED
Conditions: Seasonal Allergic Rhinitis
Interventions: DRUG: Nasal CO2|DRUG: Inactive Placebo Gas
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Arsenic Trioxide, Ascorbic Acid, Dexamethasone, and Thalidomide in Myelofibrosis/Myeloproliferative Disorder
Status: COMPLETED
Conditions: Chronic Myeloproliferative Disorders|Leukemia|Myelodysplastic Syndromes|Myelodysplastic/Myeloproliferative Diseases
Interventions: DIETARY_SUPPLEMENT: ascorbic acid|DRUG: arsenic trioxide|DRUG: dexamethasone|DRUG: thalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cervical Plexus Block (CPB) in Whiplash Associated Disorder (WAD)
Status: COMPLETED
Conditions: Whiplash Associated Disorder
Interventions: PROCEDURE: Cervical Plexus Block with Local Anaesthesia|PROCEDURE: Cervical Plexus Block with Depot Steroids
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Neuroprotection With Minocycline Therapy for Acute Stroke Recovery Trial
Status: TERMINATED
Conditions: Acute Stroke
Interventions: DRUG: Minocycline (Borymycin)|DRUG: Matched placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Liposomal Irinotecan, Fluorouracil and Leucovorin in Treating Patients With Refractory Advanced High Grade Neuroendocrine Cancer of Gastrointestinal, Unknown, or Pancreatic Origin
Status: ACTIVE_NOT_RECRUITING
Conditions: Locally Advanced Digestive System Neuroendocrine Carcinoma|Locally Advanced Pancreatic Neuroendocrine Carcinoma|Metastatic Digestive System Neuroendocrine Carcinoma|Metastatic Pancreatic Neuroendocrine Carcinoma|Refractory Digestive System Neuroendocrine Carcinoma|Refractory Pancreatic Neuroendocrine Carcinoma|Unresectable Digestive System Neuroendocrine Carcinoma|Unresectable Pancreatic Neuroendocrine Carcinoma
Interventions: DRUG: Fluorouracil|DRUG: Leucovorin|DRUG: Liposomal Irinotecan|PROCEDURE: Quality-of-Life Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Nivolumab With or Without Pazopanib in Metastatic or Unresectable Soft Tissue Sarcomas
Status: WITHDRAWN
Conditions: Soft Tissue Sarcomas
Interventions: BIOLOGICAL: Nivolumab|DRUG: Pazopanib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Kinesiotaping Method for Rib Fractures
Status: NOT_YET_RECRUITING
Conditions: Rib Fractures|Pain, Chest
Interventions: OTHER: Kinesiotaping|DRUG: Painkillers
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparing 2L Bi-Pegyte to 4L PegLyte Regiments for Outpatient Colonic Preparation
Status: COMPLETED
Conditions: Efficacy of Bowel Preparation|Ease of Bowel Preparation and Patient Tolerability
Interventions: DRUG: Standard Bowel Prep|DRUG: 2L Bi-Peglyte Bowel Prep
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose:
Clinical trial: Ambulatory Screening for Specific Learning Disabilities (SLD) and Developmental Coordination Disorder (DCD).
Status: UNKNOWN
Conditions: Specific Developmental Disorders of Speech and Language|Specific Learning Disorder|Dyslexia, Developmental|Developmental Coordination Disorder|Dyspraxia
Interventions: DIAGNOSTIC_TEST: Diagnostic of specific learning disabilities or of Developmental Coordination Disorder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Endoscopy and Endomicroscopy for Assessment of Mucosal Healing in Inflammatory Bowel Disease (IBD)
Status: WITHDRAWN
Conditions: Inflammatory Bowel Disease|Crohn's Disease|Ulcerative Colitis
Interventions: DEVICE: Endoscopy (EPK-i, Pentax, Tokyo, Japan)|DEVICE: Endomicroscopy (iCLE, Pentax, Tokyo, Japan)|DEVICE: Endoscopy (EPK-i, Pentax, Tokyo, Japan)|DEVICE: Endomicroscopy (iCLE, Pentax, Tokyo, Japan)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Postoperative Pain Following Restoration With Composite Resin Versus Sonic Fill
Status: UNKNOWN
Conditions: Postoperative Pain
Interventions: PROCEDURE: Sonic Fill Restoration|PROCEDURE: Composite Resin Restoration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Therapeutic Efficacy of Phytosterols on Metabolic Syndrome
Status: COMPLETED
Conditions: Metabolic Syndrome x
Interventions: DIETARY_SUPPLEMENT: Phytosterols|DIETARY_SUPPLEMENT: Titanium Dioxide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Effectiveness and Safety of FLECTOR Patch for Treatment of Acute Back Strain
Status: COMPLETED
Conditions: Acute Back Strain
Interventions: DRUG: FLECTORÂ® Patch (diclofenac epolamine topical patch) 1.3%
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SAINT for MDD in an Inpatient Setting Follow-on
Status: RECRUITING
Conditions: Major Depressive Disorder|Major Depressive Episode|Suicidal Ideation
Interventions: DEVICE: Active SAINT Stimulation|DEVICE: Sham SAINT Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Genetic Testing to Select Therapy for the Treatment of Advanced or Metastatic Kidney Cancer, OPTIC RCC Study
Status: RECRUITING
Conditions: Advanced Clear Cell Renal Cell Carcinoma|Metastatic Clear Cell Renal Cell Carcinoma|Stage III Renal Cell Cancer AJCC v8|Stage IV Renal Cell Cancer AJCC v8
Interventions: DRUG: Cabozantinib|BIOLOGICAL: Ipilimumab|BIOLOGICAL: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Effectiveness of Ranolazine Plus Metoprolol Combination vs. FlecainidE pluS Metoprolol Combination in ATrial Fibrillation Recurrences FOllowing PhaRmacological or Electrical CardioverSion of AtRial Fibrillation
Status: WITHDRAWN
Conditions: Atrial Fibrillation|Recurrence
Interventions: DRUG: Ranolazine plus Metoprolol Combination|DRUG: FlecainidE pluS Metoprolol Combination
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Digital Mirror Therapy With Uni- and Bilateral Mirror Visual Feedback After Stroke: Treatment Effects and EEG Evidence
Status: COMPLETED
Conditions: Stroke|Cerebrovascular Disorders|Central Nervous System Diseases
Interventions: BEHAVIORAL: Uni-MVF condition and unimanual training mode using the new MT system (UM-UT)|BEHAVIORAL: Uni-MVF condition and bimanual training mode using the new MT system (UM-BT)|BEHAVIORAL: Bi-MVF condition and bimanual training mode using the new MT system (BM-BT)|BEHAVIORAL: Traditional MT using a mirror box
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Prevention of Venous Thromboembolism in Patients Undergoing Elective Total Hip Replacement Surgery
Status: COMPLETED
Conditions: Venous Thromboembolism
Interventions: DRUG: YM150|DRUG: Placebo|DRUG: Enoxaparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Mesenchymal Stem Cells and Myocardial Ischemia
Status: COMPLETED
Conditions: Chronic Myocardial Ischemia|Left Ventricular Dysfunction
Interventions: GENETIC: Mesenchymal stem cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pepinemab in Combination With Pembrolizumab in Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck
Status: RECRUITING
Conditions: Recurrent/Metastatic Squamous Cell Carcinoma of the Head and Neck (HNSCC)
Interventions: DRUG: pepinemab + pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Coated Metal Ureteral Stent in the Treatment of Radiation Induced Ureteral Stricture
Status: RECRUITING
Conditions: Ureteral Stricture|Hydronephrosis|Radiation Exposure
Interventions: DEVICE: Coated metal ureteral stent(CMUS)|DEVICE: Double-J stent(DJS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Exercise and Presleep Nutrition on Muscle Connective Tissue Remodelling
Status: RECRUITING
Conditions: Interventional
Interventions: DIETARY_SUPPLEMENT: Collagen and Vitamin C|DIETARY_SUPPLEMENT: Carbohydrate Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study Comparing Ceramic-on-metal Articulation to Metal-on-metal Articulation in Cementless Primary Hip Arthroplasty
Status: UNKNOWN
Conditions: Osteoarthritis
Interventions: DEVICE: Ceramic On Metal|DEVICE: Metal on Metal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aloe Vera in Chronic Periodontitis With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Chronic Periodontitis
Interventions: DRUG: aloe vera|DRUG: placebo gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Examining the Effects of Three Soft Tissue Treatments on Functional Movement and Functional Performance Enhancement
Status: COMPLETED
Conditions: Functional Performance
Interventions: DEVICE: Astym|DEVICE: Stick|DEVICE: Massage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Antibiotic Bladder Instillations vs. Oral Suppression for the Treatment of Recurrent Urinary Tract Infections
Status: UNKNOWN
Conditions: Recurrent Urinary Tract Infection
Interventions: DRUG: Intravesical antibiotic instillation|DRUG: Antibiotic oral suppressive therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy of Dapagliflozin in Triple Therapy to Treat Subjects With Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: Dapagliflozin|DRUG: Placebo matching with Dapagliflozin|DRUG: Saxagliptin|DRUG: Metformin immediate release (IR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Solrikitug in Participants With COPD (ZION)
Status: NOT_YET_RECRUITING
Conditions: COPD
Interventions: DRUG: Biological: Solrikitug low dose|DRUG: Biological: Solrikitug high dose|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ambulatory Blood Pressure in HFPEF Outcomes Global Registry
Status: UNKNOWN
Conditions: Heart Failure With Preserved Ejection Fraction|Arterial Hypertension|Frailty Syndrome|Comorbidities and Coexisting Conditions
Interventions: DIAGNOSTIC_TEST: ambulatory blood pressure measurement
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Central Sensitization in Familial Mediterranean Fever (FMF)
Status: COMPLETED
Conditions: Familial Mediterranean Fever|Central Sensitisation
Interventions: DIAGNOSTIC_TEST: Central Sensitization Inventory|OTHER: Short form-36|OTHER: Pittsburgh Sleep Quality Index|OTHER: Health assessment questionnaire|OTHER: Hospital anxiety and depression scale|DIAGNOSTIC_TEST: Fibromyalgia rapid screening tool|OTHER: Familial Mediterranean Fever Quality of life scale
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Cardiovascular Impact of Obstructive Sleep Apnea Treatment in Normotensive Patients
Status: COMPLETED
Conditions: Obstructive Sleep Apnea
Interventions: DEVICE: CPAP|DEVICE: CPAP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of Eye Prophylaxis in the Newborn
Status: COMPLETED
Conditions: Chlamydia Infections|Ophthalmia Neonatorum
Interventions: DRUG: Erythromycin Ointment|DRUG: Silver Nitrate Drops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Omega-3 and Cardiovascular Risk Factors and Kidney Related Biomarkers
Status: COMPLETED
Conditions: Cardiovascular Risk Factor and Kidney Related Biomarkers
Interventions: OTHER: fish|OTHER: walnut|OTHER: fish-walnut
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Early Conversion to Everolimus From Cyclosporine in de Novo Renal Transplant Recipients
Status: COMPLETED
Conditions: Renal Function
Interventions: DRUG: everolimus|DRUG: cyclosporine A|DRUG: Enteric Coated Mycophenolate Sodium (EC-MPS)|DRUG: corticosteroids|DRUG: Basiliximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sacubitril/Valsartan Versus Valsartan in Heart Failure
Status: COMPLETED
Conditions: Heart Failure
Interventions: DRUG: Sacubitril / Valsartan Oral Tablet|DRUG: Valsartan 80 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Caffeine for Excessive Daytime Somnolence in Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson's Disease|Excessive Daytime Somnolence
Interventions: DRUG: Caffeine 100-200 mg BID|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Desmoteplase to Treat Acute Ischemic Stroke
Status: COMPLETED
Conditions: Stroke
Interventions: DRUG: Desmoteplase|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Influence of a Prematuration Culture With a Phosphodiesterase-3 Inhibitor (PDE3-I) on Embryonic Aneuploidy Rate and Developmental Potential
Status: TERMINATED
Conditions: Infertility
Interventions: PROCEDURE: prematuration culture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Creatine Supplementation in Pediatric Rheumatology
Status: UNKNOWN
Conditions: Juvenile Systemic Lupus Erythematosus|Juvenile Dermatomyositis
Interventions: DIETARY_SUPPLEMENT: creatine|DIETARY_SUPPLEMENT: placebo (dextrose)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Initial Intervention Efficacy for an Online PTSD Intervention for Pregnant Women
Status: TERMINATED
Conditions: Perinatal Problems|Post Traumatic Stress Disorder|Post Partum Depression
Interventions: BEHAVIORAL: PTSD Psychoeducation + Skills Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Post-Acute COVID-19, Inflammation, and Depression
Status: WITHDRAWN
Conditions: Post COVID -19 Depression
Interventions: BIOLOGICAL: allogeneic marrow stromal cells (MSCs)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study of Nutritional Status in Patients With Huntington's Disease
Status: ENROLLING_BY_INVITATION
Conditions: Huntington Disease
Interventions: DIAGNOSTIC_TEST: Body composition using a hand-held body fat monitor • Resting Metabolic Rate (RMR) using a ventilated hood system
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Early Increase in Blood Flow (EIBS) in the Duodenum in Patients With Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: PROCEDURE: EGD with EUS|DEVICE: 4D-ELF
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: PO Ixazomib in Combination With Chemotherapy for Childhood Relapsed or Refractory Acute Lymphoblastic Leukemia and Lymphoblastic Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: ALL, Childhood|Lymphoblastic Lymphoma, Childhood|Lymphoblastic Leukemia, Acute, Childhood
Interventions: DRUG: Ixazomib|DRUG: Vincristine|DRUG: Dexamethasone|DRUG: Asparaginase|DRUG: Doxorubicin|DRUG: Methotrexate (IT)|DRUG: Triple IT (Methotrexate, Hydrocortisone, Cytarabine)|DRUG: Leucovorin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination of Orally Inhaled BI1744CL/Tiotropium Bromide in Patients With Chronic Obstructive Pulmonary Disease ( COPD)
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: BI 1744 CL/tiotropium bromide fixed dose combination|DRUG: tiotropium bromide|DEVICE: Respimat® Inhaler
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Image Parkinson's Disease Progression Study
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DRUG: Rasagiline|OTHER: Placebo|DEVICE: Magnetic Resonance Imaging|DEVICE: functional Magnetic Resonance Imaging|OTHER: Physical Function Performance Test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of the Symbiotic Fermented Milk in Patients With Irritable Bowel Syndrome
Status: COMPLETED
Conditions: Irritable Bowel Syndrome
Interventions: OTHER: LCA symbiotic fermented milk|OTHER: heat-treated fermented milk
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Glycemic Control and Quality of Life in Adults With Type 1 Diabetes During Continuous Glucose Monitoring When Switching to Insulin Glargine 300 U/mL
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: DRUG: Insulin Glargine 300 UNT/ML [Toujeo]
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: TX2® Low Profile TAA Endovascular Graft
Status: COMPLETED
Conditions: Aortic Aneurysm|Penetrating Ulcer|Vascular Disease
Interventions: DEVICE: Zenith® TX2® Low Profile TAA Endovascular Graft
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Very Early Use of Rosuvastatin in Preventing Recurrence of Ischemic Stroke
Status: TERMINATED
Conditions: Stroke
Interventions: DRUG: Rosuvastatin|OTHER: Placebo tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Tyto Thermometer When Used in Clinical Care Setting
Status: UNKNOWN
Conditions: Body Temperature Measurement
Interventions: DEVICE: Temperature measurementsusing the Tyto thermometer, the standard of care thermometer and the predicate thermometer
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Multicentre Study in Otherwise Healthy Infants and Toddlers Hospitalised For and Diagnosed With RSV Lower Respiratory Tract Infection to Evaluate the Safety, Tolerability, and Clinical Activity of ALX-0171
Status: COMPLETED
Conditions: Respiratory Syncytial Virus Infection
Interventions: BIOLOGICAL: ALX-0171|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: REtinal Vein OccLUsion Treatment With Scatter Laser Guided by UWFA in combiNAtion With Ranibizumab Study
Status: COMPLETED
Conditions: Macular Edema|Branch Retinal Vein Occlusion
Interventions: DRUG: Ranibizumab|PROCEDURE: Peripheral Laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Solifenacin or Mirabegron With Local Estrogen Versus Combination Pharmacotherapy for Overactive Bladder
Status: RECRUITING
Conditions: Effect of Drug|Urinary Bladder, Overactive
Interventions: DRUG: Combined pharmacotherapy with Solifenacin and Mirabegron|DRUG: Solifenacin with vaginal estrogen cream|DRUG: Mirabegron with vaginal estrogen cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability of TAR-200 and Nivolumab in Subjects With Muscle-Invasive Bladder Cancer
Status: TERMINATED
Conditions: Bladder Cancer TNM Staging Primary Tumor (T) T2|Bladder Cancer TNM Staging Primary Tumor (T) T2A|Bladder Cancer TNM Staging Primary Tumor (T) T2B|Bladder Cancer TNM Staging Primary Tumor (T) T3|Bladder Cancer TNM Staging Primary Tumor (T) T3A|Bladder Cancer TNM Staging Primary Tumor (T) T3B|Bladder Cancer TNM Staging Regional Lymph Node (N) N0|Bladder Cancer TNM Staging Regional Lymph Node (N) N1|Bladder Cancer TNM Staging Distant Metastasis (M) M0
Interventions: DRUG: Gemcitabine-Releasing Intravesical System (GemRIS)/TAR-200|DRUG: Nivolumab Injection [Opdivo]
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Miniaturized Extracorporeal Circulation Study
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: PROCEDURE: CABG|PROCEDURE: Miniaturized extracorporeal circulation|PROCEDURE: Conventional extracorporeal circulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Quercetin on Green Tea Polyphenol Uptake in Prostate Tissue From Patients With Prostate Cancer Undergoing Surgery
Status: COMPLETED
Conditions: Adenocarcinoma of the Prostate|Recurrent Prostate Cancer|Stage I Prostate Cancer|Stage IIA Prostate Cancer|Stage IIB Prostate Cancer|Stage III Prostate Cancer|Stage IV Prostate Cancer
Interventions: DIETARY_SUPPLEMENT: green tea extract|DRUG: quercetin|OTHER: placebo|PROCEDURE: therapeutic conventional surgery|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: COL-1077 (Lidocaine Bioadhesive Gel, 10%) in Women Undergoing Transvaginal Pipelle-Directed Endometrial Biopsy
Status: COMPLETED
Conditions: Endometrial Biopsy
Interventions: DRUG: COL-1077|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sofosbuvir and Ribavirin in Treatment-Naive and Treatment-Experienced Subjects With Chronic Genotype 2 or 3 HCV Infection
Status: COMPLETED
Conditions: Hepatitis C
Interventions: DRUG: SOF|DRUG: RBV|DRUG: Placebo to match SOF|DRUG: Placebo to match RBV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Single Bolus Intravenous Ephedrine Attenuates Reduction of Core Body Temperature in Patients Undergoing Spinal Anesthesia for Arthroscopic Knee and Ankle Surgery
Status: COMPLETED
Conditions: Body Temperature Changes
Interventions: DRUG: Ephedrine|DRUG: NSS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of Olpasiran in Chinese Participants With Elevated Serum Lipoprotein(a)
Status: COMPLETED
Conditions: Elevated Serum Lipoprotein(a)
Interventions: DRUG: Olpasiran
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of Nonposterior- and Posterior-Stabilized Mobile-Bearing Total Knee Arthroplasty
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DEVICE: PFC-Sigma RP|DEVICE: LPS RP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Real Life Remote Monitoring of Mild, Moderate and Severe Infectious Complications in IBD by Patient Reported Assessment
Status: COMPLETED
Conditions: Inflammatory Bowel Diseases|Crohn Disease|Ulcerative Colitis|IBD|Digestive System Disease|Patient Reported Outcome Measures
Interventions: OTHER: Remote monitoring tool (infections questionnaire) validation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety of Insulin Detemir in Combination With Insulin Aspart and Biphasic Insulin Aspart 30 in Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: insulin detemir|DRUG: insulin aspart|DEVICE: biphasic insulin aspart
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: I-CARE 2: Mobile Telehealth to Reduce Alzheimer'S-related Symptoms
Status: RECRUITING
Conditions: Caregiver Burden|Alzheimer Disease
Interventions: BEHAVIORAL: Brain CareNotes|BEHAVIORAL: Dementia Guide Expert
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Evaluate the Relative Bioavailability, Food Effect and Effect of Ketoconazole on the Rate and Extent of Absorption of Solid Dosage Formulation(s) of JNJ-40411813
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: JNJ-40411813: Formulation A|DRUG: JNJ-40411813: Formulation B|DRUG: JNJ-40411813: Formulation C|DRUG: Ketoconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Buprenorphine Formulation Comparison: Sublingual Tablet vs. Solution - 1
Status: COMPLETED
Conditions: Opioid-Related Disorders
Interventions: DRUG: Buprenorphine formulation: liquid vs. tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Orotracheal Continuous Positive Airway Pressure (CPAP) in Newborns With Respiratory Failure
Status: UNKNOWN
Conditions: Neonatal Respiratory Failure
Interventions: DEVICE: OROTRACHEAL cpap WITH COMPENSATION BAG ( GREGORY CPAP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Quality of Life and Patency Rate After Minimally Invasive Cardiac Surgery
Status: NOT_YET_RECRUITING
Conditions: Minimally Invasive Cardiac Surgery
Interventions: PROCEDURE: MICS-CABG|PROCEDURE: sternotomy CABG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Safety and Efficacy of Follow-up Serial Infusions of Natrecor(Nesiritide) for the Management of Patients With Heart Failure
Status: COMPLETED
Conditions: Heart Failure, Congestive
Interventions: DRUG: Nesiritide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Haploidentical Hematopoietic Stem Cell Transplantation (HSCT) for Patients With Severe Sickle Cell Disease
Status: RECRUITING
Conditions: Sickle Cell Disease
Interventions: DEVICE: αβ+ T-cell depletion with Miltenyi CliniMACS system
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Daily Brief Exercise Intervention on Resident Physician Personal Resiliency and Burnout
Status: COMPLETED
Conditions: Burnout, Professional|Burnout Syndrome
Interventions: BEHAVIORAL: Prescribed Exercise Program|BEHAVIORAL: Usual Exercise Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Acceptance and Commitment Therapy (ACT) in Inflammatory Bowel Disease
Status: COMPLETED
Conditions: Inflammatory Bowel Disease
Interventions: BEHAVIORAL: Acceptance and Committment Therapy (ACT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Validation of a 13C Glucose Breath Test Compared With the Euglycaemic Clamp Test
Status: UNKNOWN
Conditions: Insulin Resistance|Type 1 Diabetes
Interventions: DIAGNOSTIC_TEST: euglycaemic clamp test|DIAGNOSTIC_TEST: 13C glucose breath test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Frequency of Vertebrospinal Anomalies in Patients Presenting With Anorectal Malformations
Status: COMPLETED
Conditions: Anorectal Malformations
Interventions: OTHER: To see the frequency of vertebrospinal anomalies in patients presenting with Anorectal Malformation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Multicenter, Investigative Study of the Safety and Efficacy of Extended Administration of Aripiprazole in Combination With Mood Stabilizer for the Treatment of Patients With Bipolar Disorder Experiencing a Manic or Mixed Episode
Status: COMPLETED
Conditions: Bipolar I Disorder
Interventions: DRUG: Aripiprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: VSV-hIFNbeta-NIS in Treating Patients With Relapsed or Refractory Multiple Myeloma, Acute Myeloid Leukemia or Lymphoma
Status: RECRUITING
Conditions: B-Cell Non-Hodgkin Lymphoma|Histiocytic and Dendritic Cell Neoplasm|Myelodysplastic Syndrome|Previously Treated Myelodysplastic Syndrome|Recurrent Adult Acute Myeloid Leukemia|Recurrent Anaplastic Large Cell Lymphoma|Recurrent Angioimmunoblastic T-Cell Lymphoma|Recurrent Mycosis Fungoides|Recurrent Plasma Cell Myeloma|Recurrent Primary Cutaneous T-Cell Non-Hodgkin Lymphoma|Recurrent T-Cell Non-Hodgkin Lymphoma|Refractory Acute Myeloid Leukemia|Refractory Anaplastic Large Cell Lymphoma|Refractory Angioimmunoblastic T-Cell Lymphoma|Refractory Mycosis Fungoides|Refractory Peripheral T-Cell Lymphoma, Not Otherwise Specified|Refractory Plasma Cell Myeloma|Refractory Primary Cutaneous T-Cell Non-Hodgkin Lymphoma|Refractory T-Cell Non-Hodgkin Lymphoma
Interventions: PROCEDURE: Biopsy|PROCEDURE: Biospecimen Collection|PROCEDURE: Bone Marrow Biopsy|PROCEDURE: Computed Tomography|DRUG: Cyclophosphamide|PROCEDURE: Positron Emission Tomography|BIOLOGICAL: Recombinant Vesicular Stomatitis Virus-expressing Human Interferon Beta and Sodium-Iodide Symporter|PROCEDURE: Single Photon Emission Computed Tomography|BIOLOGICAL: Cemiplimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fasting Bioequivalence Study of Memantinol 20 mg Tablets Versus Akatinol Memantine® 20 mg Tablets In Normal Healthy Subjects
Status: COMPLETED
Conditions: Bioequivalence, AUC, Cmax, Pharmacokinetics
Interventions: DRUG: Memantinol tablets, 20 mg|DRUG: Akatinol Memantine® tablets, 20 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: THE EFFECT OF THE COGNITIVE ORIENTATION TO DAILY OCCUPATIONAL PERFORMANCE (CO-OP) APPROACH IN CHILDREN WITH ATTENTION DEFICIT AND HYPERACTIVITY DISORDER ON MOTOR PERFORMANCE AND EXECUTIVE FUNCTIONS
Status: UNKNOWN
Conditions: Cognitive Orientation|Executive Dysfunction|Motor Activity
Interventions: OTHER: COGNİTİVE ORİENTATİTON DAİLY OCCUPATİONAL PERFORMANCE APPROACH
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized, Open, Parallel, Optimal Injection Rate-Finding Study for E7337 in Dynamic CT of the Liver in Patients With Liver Disease
Status: COMPLETED
Conditions: Lesion
Interventions: DRUG: Iomeprole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study to Evaluate the Safety, Tolerability, and Pharmacokinetics in Healthy Volunteers of the Novel Self-Administered Intranasal CG- SpikeDown Antiviral Drug
Status: UNKNOWN
Conditions: Healthy
Interventions: DRUG: CG-SpikeDown, intranasal formulation|DRUG: Vehicle (Placebo)|DRUG: Standard of core (type of therapy is depend of decide of the site)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Drug Interactions Software to Limit Polypharmacy
Status: COMPLETED
Conditions: Polypharmacy|Elderly|Inpatient|Drug Interaction
Interventions: DEVICE: Medication Interaction System of Dr App (SIMDA)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Pharmacokinetic and Exploratory Electrocardiogram (ECG) Study
Status: COMPLETED
Conditions: Pharmacokinetics
Interventions: DRUG: Colchicine|DRUG: Moxifloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: THE EFFECT OF RAMP LESION REPAIR ON RETURN TO SPORTS IN ANTERIOR CRUCIATE LIGAMENT RECONSTRUCTION
Status: COMPLETED
Conditions: ACL|Meniscus Lesion|Sport Injury
Interventions: PROCEDURE: surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Famotidine vs Placebo for the Treatment of Non-Hospitalized Adults With COVID-19
Status: ACTIVE_NOT_RECRUITING
Conditions: Covid-19
Interventions: DRUG: Famotidine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Collaborative Adolescent Research on Emotions and Suicide
Status: COMPLETED
Conditions: Suicidal and Self-injurious Behaviour
Interventions: BEHAVIORAL: Dialectical Behavior Therapy|BEHAVIORAL: Individual and Group Supportive Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Validation of the Dayzz Digital Sleep Training App in Insomnia and Sleep Apnea
Status: COMPLETED
Conditions: Insomnia|Sleep Apnea
Interventions: BEHAVIORAL: Dayzz mobile sleep training|OTHER: Treatment as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Oral Venetoclax Tablets and Oral Azacitidine as Maintenance Therapy in Adult Participants With Acute Myeloid Leukemia in First Remission After Conventional Chemotherapy
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Myeloid Leukemia (AML)
Interventions: DRUG: Venetoclax|DRUG: Azacitidine|DRUG: Azacitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT