pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: UARK 2009-09 Myeloma Cure Project: Prospective Trial of Indefinite Revlimid Maintenance Versus Observation for Currently Event-Free Patients With Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Revlimid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Oral Isotretinoin for the Treatment of Facial Recalcitrant Flat Warts
Status: UNKNOWN
Conditions: Flat Wart
Interventions: DRUG: Isotretinoin capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective Psychometric Evaluation Study of a Patient-reported Outcomes (PRO) Instrument for Congenital Thrombotic Thrombocytopenic Purpura (cTTP, Upshaw-Schulman Syndrome [USS], Hereditary Thrombotic Thrombocytopenic Purpura [hTTP]
Status: COMPLETED
Conditions: Congenital Thrombotic Thrombocytopenic Purpura
Interventions: OTHER: No intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Trial to Assess Efficacy and Safety of Lacosamide in Subjects With Osteoarthritis of the Knee
Status: TERMINATED
Conditions: Osteoarthritis
Interventions: DRUG: lacosamide|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Community-Centered eHealth Smoking Cessation Intervention(CCeSCI)
Status: COMPLETED
Conditions: Smoking Cessation|Lifestyle, Healthy
Interventions: OTHER: Community-Centered eHealth Smoking Cessation Intervention (CCeSCI)|OTHER: Traditional "smoking is harmful" education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Thalamic Stimulation of Patients in Vegetative or Minimally Conscious State
Status: UNKNOWN
Conditions: Vegetative State|Minimally Conscious State
Interventions: DEVICE: Implantable neurostimulation system (Medtronic)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Disulfiram (Antabuse®) on Visual Acuity in Patients With Retinal Degeneration
Status: NOT_YET_RECRUITING
Conditions: Alcohol Use Disorder|Retinal Dystrophies|Age-Related Macular Degeneration|Retinitis Pigmentosa|Stargardt Disease
Interventions: DRUG: Oral disulfiram
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Golden Walk as Measure of Gait Rehabilitation in Parkinson's Disease
Status: UNKNOWN
Conditions: Rehabilitation|Parkinson Disease|Locomotion Disorder, Neurologic|Rhythm; Abnormal
Interventions: OTHER: Stimulation with external auditory bio-feedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of a Topical Gentamicin-Collagen Sponge Along With Systemic Antibiotic in Infected Diabetic Foot Ulcers
Status: COMPLETED
Conditions: Foot Ulcer, Diabetic|Infection
Interventions: DRUG: Gentamicin Collagen sponge|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Understanding Benzodiazepine and Non-benzodiazepine Sedative Use
Status: UNKNOWN
Conditions: Frailty|Deprescription|Aged
Interventions: BEHAVIORAL: EMPOWER Educational Brochure
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Porous Tantalum Rods Improve the Hip Joint Function of Patients With Avascular Necrosis of the Femoral Head
Status: UNKNOWN
Conditions: Femoral Neck Fracture
Interventions: DEVICE: porous tantalum rod|PROCEDURE: core decompression
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Minimizing Toxicity in HLA-identical Related Donor Transplantation for Children With Sickle Cell Disease
Status: RECRUITING
Conditions: Sickle Cell Disease
Interventions: DRUG: Alemtuzumab, low dose total body irradiation, Sirolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CYT003-QbG10, a TLR9-agonist, for Treatment of Uncontrolled Moderate to Severe Allergic Asthma
Status: TERMINATED
Conditions: Moderate to Severe Allergic Asthma
Interventions: BIOLOGICAL: CYT003|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Association Between Serum and Neuroimaging Measurements of the GABAergic System
Status: NOT_YET_RECRUITING
Conditions: GABAergic System
Interventions: OTHER: Acute Oral gamma-aminobutyric acid (Natural Health Product in Canada)|OTHER: Acute Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Marginal Bone Loss in Dental Implants
Status: UNKNOWN
Conditions: Dental Implants
Interventions: DEVICE: External-Connection non-submerged Imp|DEVICE: Internal Connection Submerged implants|DEVICE: Internal Connection non-Submerged Impl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: An Efficacy and Safety Study of Injectable Ravagalimab to Assess Change in EULAR Sjogren's Syndrome Disease Activity Index (ESSDAI) in Adult Participants With Moderately to Severely Active Primary Sjogren's Syndrome (pSS)
Status: WITHDRAWN
Conditions: Sjogren's Syndrome (SS)
Interventions: DRUG: Ravaglimab|DRUG: Ravagalimab|DRUG: Placebo|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Real World Treatment Experience of Patients With Breast, Lung, or GI Cancer or Multiple Myeloma Using Remote Symptom Monitoring
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer|Lung Cancer|Gastrointestinal Cancer|Multiple Myeloma
Interventions: OTHER: survey
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Analgesia After Total Shoulder Arthroplasty
Status: COMPLETED
Conditions: Total Shoulder Arthroplasty
Interventions: PROCEDURE: Interscalene Block (ISB) - 0.375% Ropivacaine + additives|PROCEDURE: Interscalene Block (ISB) - 0.2% Ropivacaine + additives|PROCEDURE: Interscalene Block (ISB) - 0.1% Ropivacaine + additives|PROCEDURE: Interscalene Block (ISB) - Systemic Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Nanrilkefusp Alfa (SOT101) in Combination With Cetuximab to Evaluate the Efficacy and Safety in Patients With Colorectal Cancer
Status: TERMINATED
Conditions: Colorectal Cancer
Interventions: DRUG: Nanrilkefusp alfa|DRUG: Cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of a PBT Combined With FES on Reactive Balance Persons With in Stroke
Status: RECRUITING
Conditions: Stroke
Interventions: PROCEDURE: 4-week Perturbation-based balance training|DEVICE: Neuromuscular electrical stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Hydroxychloroquine in Covid-19 Patients
Status: UNKNOWN
Conditions: COVID19
Interventions: DRUG: Hydroxychloroquine 200 Mg Oral Tablet|DRUG: Azithromycin 500Mg Oral Tablet|DIETARY_SUPPLEMENT: Glucose tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Non-invasive Diagnostics of Pulmonary Hypertension With Dual Energy Computed Tomography
Status: COMPLETED
Conditions: Pulmonary Arterial Hypertension
Interventions: RADIATION: Dual-energy computed tomography investigation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Pilot Study of Patients Chronic Hepatitis C in Co-infected HIV Patients Relapsers After Previous Therapies
Status: COMPLETED
Conditions: Chronic Hepatitis C|HIV Infections
Interventions: DRUG: Peginterferon alfa-2a plus ribavirin adjusted to body weight
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Surgery or Noninvasive Therapy for Varicose Veins
Status: UNKNOWN
Conditions: Varicose Vein
Interventions: PROCEDURE: crossectomy and short stripping|PROCEDURE: ultrasound guided sclerotherapy with foam|PROCEDURE: endovenous laser therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 18F-FDG Uptake Measurements in Malignant Solid Tumors on PET/CT and PET/MR
Status: COMPLETED
Conditions: Solid Tumor, Adult
Interventions: RADIATION: Fludeoxyglucose F 18|DEVICE: Positron Emission Tomography|DEVICE: Computerized Tomography|DEVICE: Magnetic Resonance Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Psychosocial Treatment by the Case Manager in Patients After a Suicide Attempt
Status: COMPLETED
Conditions: Suicide, Attempted
Interventions: OTHER: proactive psychosocial intervention by care managers|BEHAVIORAL: case management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Capsule Endoscopy With PillCam® Colon 2 in Visualization of the Colon
Status: COMPLETED
Conditions: Colorectal Lesions
Interventions: DEVICE: PillCam Colon 2|DEVICE: Colonoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: A Dose Escalation Study of OMP-52M51 in Subjects With Lymphoid Malignancies
Status: COMPLETED
Conditions: Relapsed or Refractory Lymphoid Malignancies
Interventions: DRUG: OMP-52M51
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Postprandial 'Exercise Snacks' on Protein and Glucose Metabolism Following a Period of Step Reduction in Older Adults
Status: RECRUITING
Conditions: Inactivity, Physical|Aging|Healthy Aging|Sarcopenia|Muscular Atrophy|Neuromuscular Manifestations|Neurologic Manifestations|Nervous System Diseases|Atrophy|Pathological Conditions, Anatomical
Interventions: BEHAVIORAL: Metabolic Trial|BEHAVIORAL: 15 sit-to-stands with calf raises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Impact of Dried Moringa Oleifera Leaves in Enhancing Hemoglobin Status
Status: COMPLETED
Conditions: Anemia, Iron Deficiency
Interventions: DIETARY_SUPPLEMENT: Dried Moringa oleifera leaves
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Metformin vs Metformin Combined With GLP-1RA (Glucagon-like Peptide 1 Receptor Agonist) on Overweight/Obese PCOS Patients
Status: UNKNOWN
Conditions: Polycystic Ovary Syndrome
Interventions: DRUG: Metformin|DRUG: Exenatide 2 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of tPBM for Epileptiform Activity in Autism
Status: RECRUITING
Conditions: Autism Spectrum Disorder|EEG With Periodic Abnormalities|Epilepsy|Neurodevelopmental Disorders|Neurological Disorder
Interventions: DEVICE: noninvasively delivered near infra-red (NIR) light - transcranial Photobiomodulation (tPBM)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Subcutaneous Contouring Using High Intensity Focused Ultrasound
Status: COMPLETED
Conditions: Body Sculpting
Interventions: DEVICE: LipoSonix (Ultrasound treatment of Subcutaneous Adipose Tissue)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Radiofrequency Identification Technology in Locating Non-palpable Breast Lesions in Patients Undergoing Surgery
Status: COMPLETED
Conditions: Breast Neoplasm|Lesion
Interventions: DEVICE: Implanted Medical Device|PROCEDURE: Mammography|OTHER: Questionnaire Administration|PROCEDURE: Radiofrequency (RFID) -Guided Localization|PROCEDURE: Ultrasonography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effect of Alogliptin on Pulmonary Function in Obese Patients With Type 2 Diabetes Inadequately Controlled by Metformin Monotherapy
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Alogliptin and Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of a Multifactorial Program of Hand Hygiene on Infections in Children Attending in Day-care Centres
Status: COMPLETED
Conditions: Respiratory Tract Infections|Gastroenteritis
Interventions: OTHER: hand sanitizer|OTHER: liquid soap
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: National, Multicenter PMS Study "Patient Reported Outcome" in Breast Reconstruction Following Mastectomy With TiLOOP Bra
Status: COMPLETED
Conditions: Breast Reconstruction After Mastectomy
Interventions: DEVICE: TiLOOP Bra
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Feasibility Study on the Safety and Preliminary Efficacy of Bilateral Subthalamotomy Using MRgFUS for Treatment of PD
Status: UNKNOWN
Conditions: Parkinson Disease|Neurologic Manifestations
Interventions: DEVICE: Exablate Bilateral Subthalamotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: In Situ Erosion Study to Investigate the Effectiveness of an Experimental Toothpaste
Status: COMPLETED
Conditions: Tooth Erosion
Interventions: DRUG: 0.254% w/w sodium fluoride and 5% KNO3|DRUG: 0.454% w/w stannous fluoride|DRUG: 5% KNO3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Beneficial Effect of Adding Pentoxifylline to Processed Semen Samples on ICSI Outcome in Infertile Males
Status: COMPLETED
Conditions: Pentoxifylline Allergy
Interventions: OTHER: effect of pentoxifylline on ICSI outcome
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Higher or Lower Dose Cladribine, Cytarabine, and Mitoxantrone in Treating Medically Less Fit Patients With Newly Diagnosed Acute Myeloid Leukemia or Myeloid Neoplasm
Status: COMPLETED
Conditions: Acute Leukemia of Ambiguous Lineage|Acute Myeloid Leukemia|Myeloid Neoplasm
Interventions: DRUG: Cladribine|DRUG: Cytarabine|BIOLOGICAL: Granulocyte Colony-Stimulating Factor|DRUG: Mitoxantrone Hydrochloride|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Continuous Suturing Versus Interrupted Clips for Brachiocephalic AV Fistula Creation
Status: WITHDRAWN
Conditions: Arteriovenous Fistula
Interventions: DEVICE: AV Fistula creation with sutures|DEVICE: AV Fistula creation with clips
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety and Performance of a GLOBAL Mapping and Ablation Device for the Treatment of Atrial Fibrillation (GLOBAL-AF)
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DEVICE: Global mapping and ablation device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Goal Directed Therapy Versus Standard Care in Lung Resection Surgery (GDT-thorax Study).
Status: COMPLETED
Conditions: Goal Directed Therapy|Fluid Therapy
Interventions: PROCEDURE: Standard care|PROCEDURE: Goal directed therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy and Safety Study of WVE-210201 (Suvodirsen) With Open-label Extension in Ambulatory Patients With Duchenne Muscular Dystrophy
Status: TERMINATED
Conditions: Duchenne Muscular Dystrophy
Interventions: DRUG: WVE-210201 (suvodirsen)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dose-finding of PB-119 Administered Subcutaneously Once-weekly Versus Placebo in Drug-naïve T2DM Subjects
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: PB-119 75ug|DRUG: PB-119 150ug|DRUG: PB-119 200ug|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: NIR Fluorescence Imaging With ICG for the Intraoperative Identification of Gastrointestinal Stromal Cell Tumours
Status: UNKNOWN
Conditions: GIST
Interventions: PROCEDURE: Intraoperative near-infrared fluorescence imaging using indocyaninegreen
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of New Analgesic Strategy Compared to the Usal Antalgic Strategy
Status: COMPLETED
Conditions: Sickle Cell Anemia
Interventions: DRUG: Rapid optimized analgesic strategy|DRUG: current analgesic strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low Intensity Focused Ultrasound Pulses (LIFUP) to Modulate Pain
Status: COMPLETED
Conditions: Healthy Adults
Interventions: DEVICE: LIFUP|DEVICE: Sham LIFUP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Pilot, Exploratory, Non-Randomized Study of PET/CT With the Investigational Agent [18F] Fluciclatide to Correlate With Response to Anti-Cancer Therapy
Status: WITHDRAWN
Conditions: Advanced Cancers
Interventions: DRUG: [18F] Fluciclatide|PROCEDURE: PET/CT Scan|BEHAVIORAL: Phone Calls
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Phase I Study to Evaluate Safety, Tolerability and Pharmacokinetics of ONO-4053 in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Adult Subjects
Interventions: DRUG: ONO-4053|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Endostapled Anastomoses for Laparoscopic Gastric Bypass (EEA-LGB)
Status: COMPLETED
Conditions: Morbid Obesity
Interventions: PROCEDURE: 3.5 mm vs 4.8 mm Stapler During Laparoscopic Gastric Bypass
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to Determine Best Tumor Response With Trastuzumab Emtansine in Human Epidermal Growth Factor Receptor 2 (HER2) Overexpressing Solid Tumors
Status: COMPLETED
Conditions: Bladder Cancer|Pancreas Cancer|Cholangiocellular Carcinoma
Interventions: DRUG: Trastuzumab Emtansine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Whole Body Hyperthermia & Combat-Related Posttraumatic Stress Disorder (PTSD)
Status: TERMINATED
Conditions: Post Traumatic Stress Disorder (PTSD)
Interventions: DEVICE: High intensity whole-body infrared heating
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tolerability of Peginterferon Plus Ribavirin for Chronic Hepatitis C and HIV for Patients Receiving Antiretroviral Medication vs Not Receiving Antiretroviral Medication
Status: TERMINATED
Conditions: Chronic Hepatitis C|HIV Infections
Interventions: DRUG: peg interferon plus ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Irradiation of Large Lung Tumors or Two or More Lung Metastases Simultaneously
Status: COMPLETED
Conditions: Lung Cancer|Metastatic Lung Cancer
Interventions: RADIATION: Stereotactic Body Radiotherapy (SBRT)|RADIATION: Stereotactic Body Radiotherapy (SBRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Low-fat and Full-fat Milk on Lipids and Cardiac Function in Patients With Coronary Artery Disease
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DIETARY_SUPPLEMENT: 500 mL/day of full-fat milk from corn-fed cows (fat >3.8%) for 12 weeks|DIETARY_SUPPLEMENT: 500 mL/day of full-fat milk from grass-fed cows (fat >3.8%) for 12 weeks|DIETARY_SUPPLEMENT: 500 mL/day of low-fat milk (fat <1.5%) for 12 weeks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Multimodal Versus Opioid aNalgesia in carDiAc Surgery
Status: COMPLETED
Conditions: Postoperative Pain|Postoperative Delirium
Interventions: DRUG: Dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Comparing R-mabHD and a Combination of ABVD in Hodgkin's Disease
Status: UNKNOWN
Conditions: Hodgkin's Disease
Interventions: DRUG: R-mabHD|DRUG: ABVD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: STL Registration Measures Mandibular Bone Loss After Denture Adjustment. 3D Analysis Quantifies Resorption Post-equilibration.
Status: RECRUITING
Conditions: Resorption of Mandible
Interventions: OTHER: Occlusal equilibration of complete denture using articulating paper|OTHER: Occlusal equilibration of complete denture using occulosense
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of Oral Ergocalciferol to Treat Pruritis in Hemodialysis Patients
Status: COMPLETED
Conditions: Pruritis
Interventions: DRUG: 50,000 Units Ergocalciferol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Dentifrice Usage Regime on Delivery and Efficacy of Fluoride
Status: COMPLETED
Conditions: Dental Caries
Interventions: DRUG: Sodium fluoride / silica and carbopol, 0.5g|DRUG: Sodium fluoride / silica and carbopol, 1.5g|DRUG: Sodium fluoride / silica and carbopol, 1.5g|OTHER: Fluoride free dentifrice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Mepolizumab in the Treatment of Patients With Severe Uncontrolled CRSwNP: a Multicentric Real Life Observational Study
Status: NOT_YET_RECRUITING
Conditions: Chronic Rhinosinusitis With Nasal Polyps
Interventions: DRUG: Mepolizumab Auto-Injector
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: HEalthy Aging Team Supported Home-care Services (HEAT-YASAM)
Status: ENROLLING_BY_INVITATION
Conditions: Frailty|Dementia|Depression|Malnutrition|Old Age; Debility|Drug Use
Interventions: DIAGNOSTIC_TEST: Comprehensive Geriatric Assessment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Protein Digestibility of Whey and Zein.
Status: COMPLETED
Conditions: Biological Availability
Interventions: DIETARY_SUPPLEMENT: whey protein isolate|DIETARY_SUPPLEMENT: Zein|OTHER: protein-free
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Digital Cognitive Behavioral Therapy for Insomnia (dCBT-I) for Chronic Insomnia ：A Randomized Controlled Trial
Status: COMPLETED
Conditions: Chronic Insomnia
Interventions: BEHAVIORAL: smartphone-based dCBT-I from a Wechat applet|BEHAVIORAL: sleep education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Positron Nuclide Labeled DOTA-FAPI PET Study in Colocrectal Cancer
Status: UNKNOWN
Conditions: Tumor, Solid|Positron-Emission Tomography|Colorectal Cancer
Interventions: DIAGNOSTIC_TEST: 18F-FDG and 68Ga-DOTA-FAPI04 PET/CT|DIAGNOSTIC_TEST: 18F-FDG and 18F-DOTA-FAPI04 PET/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation of [18F]PI-2620 as a Potential Positron Emission Computed Tomography Radioligand for Imaging Tau Protein in the Brain
Status: COMPLETED
Conditions: Healthy Volunteer|Alzheimer Disease|Frontotemporal Dementia|Parkinson Disease
Interventions: DRUG: [18F]PI-2620
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Exploratory Study on the Safety, Tolerability, and Pharmacodynamics of IMB-1018972 in Subjects With Angina Due to Obstructive Coronary Artery Disease (IMPROVE-Ischemia)
Status: COMPLETED
Conditions: Ischemia|Coronary Artery Disease
Interventions: DRUG: IMB-1018972|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: S9623, Combination Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Women With Breast Cancer
Status: TERMINATED
Conditions: Breast Cancer
Interventions: BIOLOGICAL: filgrastim|DRUG: carboplatin|DRUG: carmustine|DRUG: cisplatin|DRUG: cyclophosphamide|DRUG: doxorubicin hydrochloride|DRUG: paclitaxel|DRUG: tamoxifen citrate|DRUG: thiotepa|PROCEDURE: autologous bone marrow transplantation|PROCEDURE: peripheral blood stem cell transplantation|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Recurrent Wheezing in Infants: Risk Factors and Prevention With Probiotics.
Status: COMPLETED
Conditions: Respiratory Tract Diseases|Wheezing
Interventions: DRUG: Beclomethasone|DRUG: Probiotics|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Calcium Supplementation for a Healthy Weight-Lite (CaSHeW Lite)
Status: COMPLETED
Conditions: Obesity|Overweight
Interventions: DIETARY_SUPPLEMENT: Reduced energy (lite) OJ fortified with Calcium and Vitamin D|BEHAVIORAL: Nutrition Counseling|DIETARY_SUPPLEMENT: Reduced energy (lite) OJ without Calcium and Vitamin D
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of Manufacturing Processes for a Reusable Multifocal Optical Design in a Presbyopic Population
Status: COMPLETED
Conditions: Visual Acuity
Interventions: DEVICE: JJV Investigational senofilcon A Multifocal Lens1|DEVICE: JJV Investigational senofilcon A Multifocal Lens2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Strong Hearts for New York: A Rural Heart Disease Prevention Study
Status: COMPLETED
Conditions: Heart Disease|Cardiovascular Disease|Sedentary Lifestyle|Overweight|Obesity
Interventions: BEHAVIORAL: Group 1 (Intervention)|BEHAVIORAL: Group 2 (Delayed intervention)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Yttrium-90 Anti-CD45 Monoclonal Antibody BC8 Followed by Donor Stem Cell Transplant in Treating Patients With High-Risk AML, ALL, or MDS
Status: COMPLETED
Conditions: Chronic Myelomonocytic Leukemia|Previously Treated Myelodysplastic Syndrome|Recurrent Adult Acute Lymphoblastic Leukemia|Recurrent Adult Acute Myeloid Leukemia|Refractory Anemia With Excess Blasts|Secondary Acute Myeloid Leukemia
Interventions: PROCEDURE: Allogeneic Bone Marrow Transplantation|PROCEDURE: Allogeneic Hematopoietic Stem Cell Transplantation|DRUG: Cyclosporine|DRUG: Fludarabine Phosphate|BIOLOGICAL: Indium In 111 Anti-CD45 Monoclonal Antibody BC8|OTHER: Laboratory Biomarker Analysis|DRUG: Mycophenolate Mofetil|PROCEDURE: Peripheral Blood Stem Cell Transplantation|OTHER: Pharmacological Study|RADIATION: Total-Body Irradiation|RADIATION: Yttrium Y 90 Anti-CD45 Monoclonal Antibody BC8
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Equivalence of a Generic Ciclopirox Olamine Cream Compared to the Reference Ciclopirox Cream 0.77% for the Treatment of Tinea Pedis
Status: COMPLETED
Conditions: Tinea Pedis
Interventions: DRUG: Ciclopirox Olamine Cream|DRUG: Loprox Cream 0.77%|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Computer Assisted Family Intervention to Treat Self-Harm Disparities in Latinas and Sexual/Gender Minority Youth
Status: COMPLETED
Conditions: Self Harm|Depression|Emotion Dysregulation|Behavior Problem
Interventions: BEHAVIORAL: Computer Assisted CIFFTA|BEHAVIORAL: Behavioral: Traditional face-to-face treatment-no technology
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Symptom Improvements in Gastroesophageal Reflux Disease (GERD) Patients
Status: COMPLETED
Conditions: Gastroesophageal Reflux Disease (GERD)
Interventions: DRUG: AZD3355
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Effect of Transdermal Magnesium Chloride on Quality of Life in Patients With Fibromyalgia
Status: COMPLETED
Conditions: Fibromyalgia|Fibromyalgia Syndrome
Interventions: OTHER: Transdermal Magnesium Chloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety Study to Evaluate LY3114062 in Participants With Inflammatory Arthritis
Status: COMPLETED
Conditions: Inflammatory Arthritis
Interventions: DRUG: LY3114062 SC|DRUG: Placebo|DRUG: LY3114062 IV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Steroid Free Immunosuppression or Calcineurin Inhibitor Minimization After Basiliximab Induction Therapy in Kidney Transplantation: Comparison With a Standard Quadruple Immunosuppressive Regimen
Status: COMPLETED
Conditions: Renal Insufficiency|Kidney Transplantation
Interventions: DRUG: tacrolimus OD, mycophenolic acid, prednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Endotracheal Tube With Stylet in Morbidly Obese Patients
Status: NOT_YET_RECRUITING
Conditions: Intubation; Difficult or Failed|Obesity, Morbid
Interventions: PROCEDURE: Endotracheal tube with stylet|PROCEDURE: Endotracheal tube alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Enhancing School-Based Violence Prevention
Status: RECRUITING
Conditions: Aggressive Childhood Behavior
Interventions: BEHAVIORAL: Mental Health Enhanced Positive Behavioral Interventions and Supports (PBIS-MH)|BEHAVIORAL: Racial/Ethnic Discrimination Interventions (RED)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Percutaneous Microelectrolysis in Agility, Joint Range and Strength
Status: COMPLETED
Conditions: Hamstring Contractures
Interventions: DEVICE: Muscle belly Microelectrolysis|DEVICE: Tendon Microelectrolysis|OTHER: Stretching exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Exercise-intensity on Physiological Adaptations in Overweight and Obese
Status: COMPLETED
Conditions: Overweight|Obesity
Interventions: BEHAVIORAL: Long distanse moderate training|BEHAVIORAL: Long interval training|BEHAVIORAL: Short interval training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pain Felt During Removal of the Products From Infant's Skin Used in Nasogastric Tube Fixation
Status: COMPLETED
Conditions: Pain, Acute
Interventions: DEVICE: Water-based barrier tape|DEVICE: Hydrocolloid barrier tape|DEVICE: Silk tape
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Phase 1-2 Study of Total Bone Marrow Irradiation With Helicoidal Tomotherapy in 1st Myeloma Relapse
Status: TERMINATED
Conditions: Multiple Myeloma in Relapse
Interventions: DRUG: Melphalan|BIOLOGICAL: Autologous Hematopoietic Stem cell
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Drug-Drug Interaction of RO5503781 and Posaconazole, the Relative Bioavailability of New Formulations of RO5503781 and the Food-Effect on the Pharmacokinetics of RO5503781 in Patients With Solid Tumors
Status: COMPLETED
Conditions: Neoplasms
Interventions: DRUG: RO5503781|DRUG: RO5503781|DRUG: RO5503781|DRUG: RO5503781|DRUG: posaconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Influence of Glucose on Metabolism and Clinical Symptoms of Patients With Parkinson's Disease
Status: RECRUITING
Conditions: Parkinson Disease|Nutritional and Metabolic Diseases|Sugar Intake
Interventions: DIAGNOSTIC_TEST: Oral Glucose Tolerance Test|OTHER: Placebo Oral Glucose Tolerance Test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study for The Prevention Of Nausea in Cancer Patients Receiving Highly Emetogenic Cisplatin Based Chemotherapy
Status: COMPLETED
Conditions: Nausea and Vomiting|Chemotherapy-Induced
Interventions: DRUG: Aprepitant|DRUG: Ondansetron|DRUG: GW679769|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Platelets Rich Plasma as a Therapeutic Tool in Diabetic Foot Ulcers
Status: UNKNOWN
Conditions: Diabetic Foot Ulcer
Interventions: OTHER: 20-100 ml venous blood will be drawn the from patient into sterilized centrifuge tube ,following centrifuge to separate PRP and at the bed side and tricked onto the ulcer twice weekly|OTHER: standard treatment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Vestibular Implants Tested in Human Subjects
Status: WITHDRAWN
Conditions: Vestibular Disorder|Vestibular Ataxia|Vestibular Loss, Bilateral
Interventions: DEVICE: Vestibular prosthesis/implant|DEVICE: Vestibular Implant Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pomegranate Supplementation and Well-Being Among Medical Students and Residents
Status: ACTIVE_NOT_RECRUITING
Conditions: Antioxidant|Burnout, Professional|Psychological Distress
Interventions: DIETARY_SUPPLEMENT: Pomella pomegranate extract|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Pharmacodynamic Interaction of REMI and DMED
Status: COMPLETED
Conditions: Anesthesia
Interventions: DRUG: Dexmedetomidine|DRUG: Remifentanil
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: CICLOPS Immune Checkpoint Inhibitors Neurotoxicity: Long-term Outcomes, Predictors, and Survival.
Status: COMPLETED
Conditions: Paraneoplastic Syndromes
Interventions: OTHER: This is a non-interventional study. We will collect clinical data exclusively, and will do so by reviewing all available patients clinical records.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Vitamin B12 and n-3 Polyunsaturated Fatty Acids on Plasma Homocysteine
Status: UNKNOWN
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Fish oil|DIETARY_SUPPLEMENT: vitaminB12
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Study of Malaria Treatment at Phuoc Long Hospital, Binh Phuoc Province, Vietnam
Status: COMPLETED
Conditions: Malaria
Interventions: DRUG: Artesunate or dihydroartemisinin-piperaquine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Contraceptive Hormone and Reward Measurement (CHARM Study)
Status: RECRUITING
Conditions: Oral Hormonal Contraceptive Use|Neural Activity|Mood|Hedonic Function
Interventions: DRUG: Levonorgestrel/ethinyl estradiol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Blood Flow Restriction Training Versus Standard Physical Therapy After Shoulder Stabilization Surgery
Status: UNKNOWN
Conditions: Anterior Shoulder Dislocation|Recurrent Shoulder Dislocation|Shoulder Subluxation|Surgery
Interventions: OTHER: Blood flow restriction therapy|OTHER: Standard Physical Thearapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Creation of a Prospective Cohort of Healthy and Sick Subjects and of a Collection of Associated Biological Resources, for the Study of the Immune System and of Its Genetic and Environmental Determinants.
Status: UNKNOWN
Conditions: Immune System and Related Disorders
Interventions: PROCEDURE: Collection of samples (blood, stool, etc.)|GENETIC: Genetic determinants analysis|PROCEDURE: Sample obtained after surgery performed in the context of care
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: HFHO vs CPAP During Thoracic Surgery
Status: COMPLETED
Conditions: Hypoxaemia During Surgery|Lung Hyperinflation
Interventions: DEVICE: CPAP|DEVICE: HFHO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Aspirin for Prevention of Postsurgical Recurrence and Metastasis in Asian Colorectal Cancer Patients: a Multi-center Randomized Trial
Status: UNKNOWN
Conditions: Colorectal Cancer
Interventions: DRUG: Acetylsalicylic acid (ASA)/aspirin 200 mg daily|DRUG: Acetylsalicylic acid (ASA)/aspirin 100 mg daily|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Metoprolol and Amlodipine on Cardiac Remodeling, Arrhythmias and Blood Pressure Variation in Hypertensive Patients With Sleep Apnea Syndrome
Status: UNKNOWN
Conditions: Sleep Apnea Syndrome|Hypertension
Interventions: DRUG: Amlodipine|DRUG: metoprolol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Ultrasound-Guided Internal Superior Laryngeal Nerve Block for Double-Lumen Bronchial Tube
Status: RECRUITING
Conditions: Postoperative Sore Throat
Interventions: PROCEDURE: internal superior laryngeal nerve block|DRUG: Lidocaine 2% Injectable Solution|DRUG: Bupivacaine 0.5% Injectable Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Trial Of Gemcitabine Plus Paclitaxel And Gemcitabine Plus Docetaxel In Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Neoplasms
Interventions: DRUG: Gemcitabine|DRUG: Paclitaxel|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nasal Inhalation of Tobramycin in Patients With Cystic Fibrosis and Pseudomonas Aeruginosa Colonization
Status: COMPLETED
Conditions: Cystic Fibrosis|Pseudomonas Aeruginosa
Interventions: DRUG: Tobramycin (Gernebcin®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Niraparib And Sintilimab In Recurrent/Metastatic Nasopharyngeal Carcinoma
Status: UNKNOWN
Conditions: Nasopharyngeal Carcinoma
Interventions: DRUG: Niraparib，Sintilimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neuromuscular Changes In Small For Gestational Age Children During Somatropin Therapy
Status: TERMINATED
Conditions: Growth Hormone Therapy|Infant, Small for Gestational Age
Interventions: DRUG: Somatropin|DRUG: Somatropin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Extreme Lateral Interbody FusionFUSION (XLIF) Versus Posterior Lumbar Interbody Fusion (PLIF)
Status: SUSPENDED
Conditions: Muscle Damage|Atrophy|Degenerative Diseases, Spinal Cord
Interventions: PROCEDURE: XLIF|PROCEDURE: PLIF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intermittent Duvelisib Dosing in Treating Patients With Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Recurrent Chronic Lymphocytic Leukemia|Recurrent Small Lymphocytic Lymphoma|Refractory Chronic Lymphocytic Leukemia|Refractory Small Lymphocytic Lymphoma
Interventions: DRUG: Duvelisib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Reduce the Reflux After a Sleeve Gastrectomy in Obese Patients
Status: WITHDRAWN
Conditions: Gastroesophageal Reflux|Obesity
Interventions: PROCEDURE: DPC|PROCEDURE: LSG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: AMG 386 Phase 2 Open-Label Renal Cell Carcinoma (RCC) Study 1st Line or After Cytokine Failure in Combination With Sunitinib
Status: COMPLETED
Conditions: Advanced Renal Cell Carcinoma
Interventions: DRUG: Sunitinib|DRUG: Trebananib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Efficacy, Safety and Tolerability of LCQ908 in NAFLD Patients
Status: COMPLETED
Conditions: Non-alcoholic Fatty Liver Disease (NAFLD)
Interventions: DRUG: LCQ908|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Two Mini-Implant Lengths in the Infra-Zygomatic Crest Region
Status: COMPLETED
Conditions: Orthodontic Appliance Complication
Interventions: DEVICE: 12*2 mm length miniscrew
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating the Safety and Pharmacokinetics of QTORIN Rapamycin 3.9% Anhydrous Gel in the Treatment of Adults With Pachyonychia Congenita
Status: RECRUITING
Conditions: Pachyonychia Congenita
Interventions: DRUG: PTX-022
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Room Light on Uterine Contractions and Labor Progression in Pregnancy
Status: NOT_YET_RECRUITING
Conditions: Pregnancy Related|Labor; Poor|Uterine Contractions Weak
Interventions: DEVICE: Room light/light bulb
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE