pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Use of a Selected Mixture of Probiotic Strains for Degrading Gluten During Digestion
Status: COMPLETED
Conditions: Probiotics
Interventions: COMBINATION_PRODUCT: Probiotic administration and gluten|COMBINATION_PRODUCT: Placebo administration and gluten
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SCREENING
Clinical trial: Comparative Study Between Continuous Epidural Anesthesia And Continuous Spinal Anesthesia Using Wiley™ Spinal Catheter
Status: COMPLETED
Conditions: Anesthesia; Adverse Effect, Spinal and Epidural
Interventions: DEVICE: Epidural (B. Braun)|DEVICE: Spinal (Wiley Spinal Catheter)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Analgesic Efficacy of Intranasal Desmopressin in Acute Renal Colic
Status: UNKNOWN
Conditions: Renal Colic|Pain
Interventions: DRUG: Desmopressin intranasal spray|DRUG: Placebo intranasal spray|DRUG: Indomethacin suppository
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Newborn Vitamin A (VA) Supplementation Pilot Project, Pakistan
Status: COMPLETED
Conditions: Vitamin A Deficiency
Interventions: DIETARY_SUPPLEMENT: Vitamin A|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Cholecalciferol and Flu Vaccine in Treating Healthy Participants
Status: TERMINATED
Conditions: Healthy, no Evidence of Disease
Interventions: DIETARY_SUPPLEMENT: cholecalciferol|OTHER: questionnaire administration|BIOLOGICAL: trivalent influenza vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Impacts of Theta-burst Stimulation on Children and Adolescents With Autism Spectrum Disorder
Status: COMPLETED
Conditions: Autism Spectrum Disorder
Interventions: DEVICE: intermittent theta burst stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Validation and Reliability of the Turkish 4AT Scale for Post-Anesthesia Awakening Delirium
Status: COMPLETED
Conditions: Delirium|Awakening, Post-Anesthesia Delayed|Delirium, Postoperative|Nurse's Role|Nursing Caries
Interventions: OTHER: 1 Grups
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effectiveness of 3M Cavilon Advanced Skin Protectant in the Treatment of Moisture-associated Skin Damage in Hospitals
Status: NOT_YET_RECRUITING
Conditions: Irritant Dermatitis|Stoma Site Dermatitis|Wound of Skin
Interventions: DEVICE: 3M Cavilon Advanced Skin Protectant|DEVICE: Standard hospital wound treatment protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Oral Akynzeo® vs Standard of Care in Preventing CINV in High-risk MEC Patients (MyRisk)
Status: ACTIVE_NOT_RECRUITING
Conditions: Chemotherapy-induced Nausea and Vomiting
Interventions: DRUG: NEPA (300mg netupitant/0.5mg palonosetron)|DRUG: Granisetron, 2 mg (oral) or 1 mg (IV) OR Palonosetron, 0.5 mg (oral), 0.25mg (IV) OR Ondansetron, 16 mg (oral) or 8 mg (IV) OR Dolasetron 100 mg (oral) OR Tropisetron 5 mg (oral or IV)|DRUG: Dexamethasone, 8 mg (oral) or equivalent IV dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Boron Neutron Capture Therapy Using CICS-1 and SPM-011 for Malignant Melanoma and Angiosarcoma
Status: COMPLETED
Conditions: Malignant Melanoma|Angiosarcoma
Interventions: OTHER: CICS-1 (investigational device),SPM-011(investigational drug)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: L-carnitine on the Prevention of Renal Scarring in Acute Pyelonephritis
Status: UNKNOWN
Conditions: Acute Pyelonephritis(APN)
Interventions: DRUG: L-carnitine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Research Study on How Well Semaglutide Works in Adolescents With Overweight or Obesity
Status: COMPLETED
Conditions: Overweight|Obesity
Interventions: DRUG: Semaglutide|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial Comparing Observation With Radiation on Pelvic Lymphocysts After Radical Hysterectomy of Cervical Cancer
Status: RECRUITING
Conditions: Cervical Cancer|Lymphocyst|Radiation Therapy
Interventions: RADIATION: Radiation Method B|DRUG: Cisplatin|RADIATION: Radiation Method A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Facial Effleurage on Acute Rhinosinusitis
Status: COMPLETED
Conditions: Rhinosinusitis Acute
Interventions: OTHER: Sham Treatment|OTHER: Facial Effleurage|DRUG: Antibiotics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A 3-arm Proof of Concept Study of AIN457, ACZ885 or Corticosteroids in Patients With Polymyalgia Rheumatica
Status: TERMINATED
Conditions: Polymyalgia Rheumatica|Inflammatory Diseases
Interventions: DRUG: AIN457|DRUG: ACZ885|DRUG: Prednisone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Leveraging EEG for Antidepressant Prediction With Duloxetine and Bupropion
Status: WITHDRAWN
Conditions: Major Depressive Disorder
Interventions: DRUG: Duloxetine|DRUG: Bupropion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Physical Activity Barriers in Adolescent Hypertension Patients
Status: ENROLLING_BY_INVITATION
Conditions: Physical Inactivity
Interventions: OTHER: Anthropometric measurement|OTHER: Level of Physical Activity|OTHER: Physical Activity Barriers Scale|OTHER: Hand Grip Strength|OTHER: Arterial stiffness
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Ceftolozane/Tazobactam (MK-7625A) in Japanese Participants With Uncomplicated Pyelonephritis and Complicated Urinary Tract Infection (MK-7625A-014)
Status: COMPLETED
Conditions: Urinary Tract Infection (UTI)|Complicated Urinary Tract Infection|Pyelonephritis|Uncomplicated Pyelonephritis
Interventions: DRUG: MK-7625A 1.5 g (ceftolozane 1 g/tazobactam 0.5 g)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase IIB Pilot of Atazanavir + Raltegravir
Status: TERMINATED
Conditions: HIV
Interventions: DRUG: Atazanavir|DRUG: Raltegravir|DRUG: Atazanavir|DRUG: Ritonavir|DRUG: Tenofovir/Emtricitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EUS Guided Core Liver Biopsy and IGB Placement for the Diagnosis and Management of NASH and Obesity
Status: COMPLETED
Conditions: Obesity|Non-Alcoholic Steatohepatitis
Interventions: DEVICE: Orbera Intragastric Balloon|PROCEDURE: Endoscopic Ultrasound Guided Core Liver Biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Use of Eculizumab in HELLP Syndrome
Status: COMPLETED
Conditions: HELLP Syndrome (HELLP), Third Trimester|Complement Abnormality|Morbidity;Newborn|Maternal Injury|Preeclampsia Severe
Interventions: DRUG: Eculizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Corneal Crosslinking in Patients With Keratoconus and Post-Refractive Ectasia
Status: COMPLETED
Conditions: Keratoconus|Post-Refractive Ectasia
Interventions: DRUG: Riboflavin|DEVICE: UVX light
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Neurotropin to Treat Chronic Neuropathic Pain
Status: TERMINATED
Conditions: Complex Regional Pain Syndrome Type I|Complex Regional Pain Syndrome Type II
Interventions: DRUG: Placebo|DRUG: Neurotropin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Posterior Plating Versus Anterior to Posterior Screws in Fixation of Posterior Column in Pilon Fractures
Status: COMPLETED
Conditions: Tibial Fractures
Interventions: PROCEDURE: Fixation of 2,3 or 4 column pilon fracture of the tibia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Acheta Domesticus Supplementation on Post-Exercise Muscle Recovery in Recreationally Active Male
Status: RECRUITING
Conditions: Muscle Soreness
Interventions: OTHER: 100 Drop Jumps|DIETARY_SUPPLEMENT: Whey supplementation|DIETARY_SUPPLEMENT: Carbohydrate supplementation|DIETARY_SUPPLEMENT: House cricket supplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Open Label Safety & Pharmacodynamic Study 24Wk w/DIO-902 Combo w/Metformin & Atorvastatin in T2DM Patients
Status: TERMINATED
Conditions: Type 2 Diabetes
Interventions: DRUG: DIO-902|DRUG: DIO-902|DRUG: DIO-902
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low Speed Drilling Versus Conventional Drilling Technique on Crestal Bone Level in Maxilla.(Group C ) A Randomized Controlled Clinical Trial
Status: UNKNOWN
Conditions: Bone Resorption
Interventions: PROCEDURE: Drilling at low speed|PROCEDURE: Drilling at conventional or high speed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluating Inflammatory and Immunological Changes of HIV-positive Patients Switching to DTG Dual Regimen Compared to Those Switching to a Triple Drugs Regimen (B/F/TAF)
Status: UNKNOWN
Conditions: HIV Infections
Interventions: DRUG: Bictegravir 50 MG / Emtricitabine 200 MG / Tenofovir Alafenamide 25 MG [Biktarvy]|DRUG: dolutegravir 50 mg / lamivudine 300 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Taxanes or Platinum in Combination With Capecitabine Followed by Capecitabine Alone as First Line Treatment for Patients With Advanced Adenocarcinoma of Stomach or Esophagogastric Junction
Status: UNKNOWN
Conditions: Gastric Cancer
Interventions: DRUG: Capecitabine|DRUG: capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of QiShen YiQi Dripping Pills in the Treatment of Diabetic Kidney Disease (Syndrome of Qi Deficiency With Blood Stasis)
Status: RECRUITING
Conditions: Diabetic Kidney Disease
Interventions: DRUG: Qishen Yiqi Dripping Pills placebo 3 bags|DRUG: Low dose Qishen Yiqi Dripping Pills 3 bags|DRUG: High dose Qishen Yiqi Dripping Pills 3 bags
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Radial Ablation for the Control of Persistent Atrial Fibrillation
Status: RECRUITING
Conditions: Persistent Atrial Fibrillation
Interventions: PROCEDURE: Pulmonary vein electrical isolation|PROCEDURE: Radial ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: the Remineralizing Self-Assembling Peptide P11-4, 2% Arginine Enriched Sodium Fluoride and Functionalized Tri Calcium Phosphate Fluoride White Spot Lesions
Status: UNKNOWN
Conditions: Prevention of White Spot Lesions
Interventions: DRUG: curodont
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Zero-fluoroscopic Cryoballoon Ablation
Status: COMPLETED
Conditions: Atrial Fibrillation Paroxysmal
Interventions: PROCEDURE: CBA was performed under intracardiac echocardiography guidance without fluoroscopy|PROCEDURE: cryoablation (CBA) was performed under fluoroscopic guidance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Esophageal Epithelium Integrity With Use of a Novel Mucosal Impedance Device
Status: ENROLLING_BY_INVITATION
Conditions: Gastro Esophageal Reflux
Interventions: DIAGNOSTIC_TEST: single catheter mucosal impedance testing|DIAGNOSTIC_TEST: balloon assembly mucosal impedance testing
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: "Clinical Evaluation of Retraction Cord Effectiveness Using Intraoral Scanner
Status: ACTIVE_NOT_RECRUITING
Conditions: Prosthesis User|Digitalism
Interventions: OTHER: retraction cordu (SURE-CORD®PLUS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Acute Effects of High-intensity Interval Training With Mindfulness-based Recovery on Executive Function in Children
Status: NOT_YET_RECRUITING
Conditions: Healthy Volunteers
Interventions: BEHAVIORAL: MF-HIIT|BEHAVIORAL: MF-only|BEHAVIORAL: HIIT-only|BEHAVIORAL: Sitting rest
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pathophysiological Study of Characteristics of the Changes in the Cutaneous Immune System After Intradermal Antigen Injections
Status: TERMINATED
Conditions: Healthy|Immunosuppressed
Interventions: BIOLOGICAL: Tuberculin antigen
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Imatinib Mesylate and Docetaxel in Non-Small Cell Lung Cancer (NSCLC)
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: Imatinib Mesylate|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Protocols for Analgesia Following Elective Cesarean Section
Status: UNKNOWN
Conditions: Postoperative Pain|Post-Cesarean Section
Interventions: DRUG: Acetaminophen|DRUG: Ibuprofen 400 mg|DRUG: Dipyrone|DRUG: Tramadol|DRUG: Morphine|DRUG: Tramal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparison Between Scalp Nerve Block and Scalp Infiltration
Status: UNKNOWN
Conditions: Aneurysm
Interventions: PROCEDURE: Scalp Nerve Block|PROCEDURE: Scalp infiltration|DRUG: Ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Sapanisertib and Ziv-Aflibercept in Treating Patients With Recurrent Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery
Status: COMPLETED
Conditions: Advanced Malignant Solid Neoplasm|Fibrolamellar Carcinoma|Metastatic Malignant Solid Neoplasm|Ovarian Carcinoma|Pancreatic Neuroendocrine Tumor|Recurrent Malignant Solid Neoplasm|Refractory Malignant Solid Neoplasm|Unresectable Solid Neoplasm
Interventions: DRUG: Sapanisertib|BIOLOGICAL: Ziv-Aflibercept
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: AccuLIF® PROSPECTIVE PATIENT OUTCOMES STUDY
Status: TERMINATED
Conditions: Degenerative Disc Disease|Spondylolisthesis, Grade 1|Retrolisthesis
Interventions: DEVICE: AccuLIF expandable TLIF cage
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Autologous Bone Marrow Mononuclear Cells in Patients With Severe Critical Limb Ischemia
Status: COMPLETED
Conditions: Critical Limb Ischemia
Interventions: OTHER: Autologous Bone Marrow Mononuclear cells (BMMNCs)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combined Intravitreal Bevacizumab With Topical Timolol-Dorzolamide Eye Drops in Diabetic Macular Edema
Status: UNKNOWN
Conditions: Diabetic Macular Edema
Interventions: DRUG: Injections of 1.25 mg of intravitreal bevacizumab with Timolol and Dorzolamide|DRUG: Injections of 1.25 mg of intravitreal bevacizumab with artificial tears
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Lipiodol® Ultra Fluid in Association With Surgical Glues During Vascular Embolization.
Status: UNKNOWN
Conditions: Congenital Hemangioma|Hemangioendothelioma|Angiosarcoma|Arteriovenous Malformation
Interventions: DRUG: Lipiodol® Ultra Fluid with surgical glues
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Natural History and Longitudinal Clinical Assessments in NCL / Batten Disease, the International DEM-CHILD Database
Status: RECRUITING
Conditions: Neuronal Ceroid Lipofuscinosis|Batten Disease|CLN1 Disease|CLN2 Disease|CLN3 Disease|CLN4 Disease|CLN5 Disease|CLN6 Disease|CLN7 Disease|CLN8 Disease|CLN10 Disease|CLN11 Disease|CLN12 Disease|CLN13 Disease|CLN14 Disease
Interventions: OTHER: Natural History
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Southern California Nutrition Incentive Program
Status: ACTIVE_NOT_RECRUITING
Conditions: Food Insecurity
Interventions: OTHER: Financial Incentive: High|OTHER: Financial Incentive: Middle|OTHER: Financial Incentive: Low
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Mesenchymal Stem Cells Transplantation in Patients With Chronic Renal Failure Due to Polycystic Kidney Disease
Status: COMPLETED
Conditions: Chronic Renal Failure|Polycystic Kidney Disease
Interventions: BIOLOGICAL: Intravenous injection autologous mesenchymal stem cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Nurse-led Programme With Carotid Ultrasound on Addressing Cardiovascular Risk in Patients With Arthritis
Status: WITHDRAWN
Conditions: Arthritis, Rheumatoid|Arthritis, Psoriatic
Interventions: DRUG: Atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Phase 2a Study to Evaluate the Safety and Tolerability of Benralizumab (MEDI-563) in Adults With Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: OTHER: Placebo|BIOLOGICAL: Benralizumab 25 mg|BIOLOGICAL: Benralizumab 100 mg|BIOLOGICAL: Benralizumab 200 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Motor-assisted Cycling and FES Cycling for Postprandial Glucose in Diabetic Patients With ADL Disability
Status: COMPLETED
Conditions: Type2 Diabetes|Disability Physical
Interventions: BEHAVIORAL: Motor-assisted cycling|BEHAVIORAL: FES cycling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Some Puberty-related Hormones Among Children and Adolescents With Chronic Kidney Diseases
Status: NOT_YET_RECRUITING
Conditions: Evaluation of Some Puberty-related Hormones Among Children and Adolescents With Chronic Kidney Diseases
Interventions: DIAGNOSTIC_TEST: serum kisspeptin levels
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: EWISE: Study of Eplerenone in Women With Chest Pain, Coronary Vascular Dysfunction and Evidence of Myocardial Ischemia
Status: COMPLETED
Conditions: Ischemic Heart Disease
Interventions: DRUG: Eplerenone|DRUG: Placebo or sugar pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prevalence of Pulmonary Embolism in Patients With Syncope
Status: COMPLETED
Conditions: Syncope|Pulmonary Embolism
Interventions: OTHER: Lung CT or V/Q scanning in patients with a high pre-test clinical probability of PE and/or a positive D-dimer
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Mindful-Compassion Art Therapy for Dementia Care (MCAT-DC) : A Waitlist Randomized Controlled Trial
Status: UNKNOWN
Conditions: Caregiver Burnout|Caregiver Stress
Interventions: BEHAVIORAL: Mindful-Compassion Art Therapy for Dementia Care (MCAT-DC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: RGD PET/MRI in Sporadic Vestibular Schwannoma
Status: UNKNOWN
Conditions: Acoustic Neuroma
Interventions: DRUG: One injection of 68Ga-NODAGA-E[c(RGDyK)]2
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of Early Stage Endometrial Cancer Based on Molecular Classification and Traditional Risk Stratification to Guide Adjuvant Radiotherapy Decisions
Status: NOT_YET_RECRUITING
Conditions: Endometrial Cancer|Adjuvant Radiotherapy|Molecular Classification
Interventions: RADIATION: Vaginal brachytherapy|RADIATION: Pelvic external beam radiotherapy|OTHER: Observation|DRUG: Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study: Oral Treatment of American Tegumentary Leishmaniasis (Cutaneous and Mucosal Forms) in the Elderly
Status: RECRUITING
Conditions: Leishmaniasis; Brazilian|Leishmaniasis, Mucocutaneous
Interventions: DRUG: Miltefosine 50mg|DRUG: Pentoxifylline 400mg|DRUG: Liposomal Amphotericin B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Community Reinforcement and Family Training for Drug Abuse Treatment Retention/HIV Risk Reduction
Status: UNKNOWN
Conditions: Heroin Dependence|Opiate Dependence|Substance Dependence
Interventions: BEHAVIORAL: CRAFT-T|BEHAVIORAL: Treatment as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Trial of the Use of Quetiapine Fumarate (SEROQUEL®) in the Treatment of Patients With Bipolar Depression
Status: COMPLETED
Conditions: Bipolar Disorder|Depression, Bipolar
Interventions: DRUG: SEROQUEL (quetiapine fumarate) Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Study of the Use of Humidified Warmed Gas and the Effect on Post-Operative Pain in Laparoscopic Cholecystectomies
Status: UNKNOWN
Conditions: Gallstone
Interventions: OTHER: Warm humidified C02|OTHER: Cool dry C02
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I Dose Escalation Study of Intratumoral VCN-01 Injections With Gemcitabine and Abraxane® in Patients With Advanced Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Adenocarcinoma|Metastatic Pancreatic Adenocarcinoma
Interventions: GENETIC: VCN-01|DRUG: Gemcitabine|DRUG: Abraxane®
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hyperpolarized Xenon-129 MRI: a New Multi-dimensional Biomarker to Determine Pulmonary Physiologic Responses to COPD Therapeutics
Status: RECRUITING
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Anoro Ellipta|DRUG: Arnuity Ellipta
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Optimizing Exposure Therapy Via Reward-focused Interventions in Individuals With Public Speaking Anxiety
Status: RECRUITING
Conditions: Public Speaking Fear
Interventions: BEHAVIORAL: reward-focused intervention|BEHAVIORAL: cognitive flexibility intervention|BEHAVIORAL: exposure|BEHAVIORAL: Psychoeducation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Psilocybin for the Treatment of Migraine Headache
Status: COMPLETED
Conditions: Migraine Headache
Interventions: DRUG: High Dose Psilocybin|DRUG: Low Dose Psilocybin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of the Diabetes Body Project Among Females With Type 1 Diabetes
Status: TERMINATED
Conditions: Feeding and Eating Disorders|Diabetes Mellitus, Type 1|Body Image
Interventions: BEHAVIORAL: Diabetes Body Project|BEHAVIORAL: Psychoeducation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of Oral LGH447 in Patients With Relapsed and/or Refractory Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: LGH447|DRUG: midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Safety and Efficacy of IPN10200 in Adult Participants With Moderate to Severe Upper Facial Lines
Status: RECRUITING
Conditions: Moderate to Severe Upper Facial Lines
Interventions: BIOLOGICAL: IPN10200|BIOLOGICAL: IPN10200 Placebo|BIOLOGICAL: Dysport
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Of Dacomitinib (PF-00299804) In Patients With Advanced Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: Dacomitinib|DRUG: Dacomitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Iressa and Taxotere Study in Patients With Metastatic Urothelial Cancer
Status: TERMINATED
Conditions: Bladder Cancer
Interventions: DRUG: Docetaxel|DRUG: ZD1839|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EMDR vs. CBT in the Treatment of Inpatients With Obesity and Binge Eating Disorder: the EMDRDCA Study.
Status: RECRUITING
Conditions: Binge-Eating Disorder
Interventions: OTHER: EMDR|OTHER: CBT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Long Term Study To Evaluate The Safety, Tolerability And Efficacy Of CP-690,550 In Patients With Moderate To Severe Plaque Psoriasis And/Or Psoriatic Arthritis
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: CP-690,550|DRUG: CP-690, 550
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Plasma Pharmacokinetics and Safety of LNZ101 and LNZ100 Ophthalmic Solutions in Healthy Adult Subjects With Presbyopia
Status: COMPLETED
Conditions: Eye Diseases|Presbyopia|Refractive Errors|Brimonidine Tartrate|Aceclidine|Ophthalmic Solutions
Interventions: DRUG: Aceclidine + Brimonidine|DRUG: Aceclidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Generating Collective Solutions to Reduce Unnecessary Antibiotic Use in Vietnam
Status: RECRUITING
Conditions: Antibiotic Use
Interventions: OTHER: Basic antimicrobial stewardship education|OTHER: Participatory action research group in commune health center and community|OTHER: Antimicrobial stewardship program in hospitals|OTHER: Community education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Therapeutic Safety and Efficacy of REP 2139 (REP 9AC') in HBV Infected Patients
Status: COMPLETED
Conditions: Hepatitis B, Chronic
Interventions: DRUG: REP 2139-Ca|DRUG: Zadaxin|DRUG: Pegasys
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single-ascending Dose Study to Investigate the Tolerability, Safety, Pharmacokinetics, and Pharmacodynamics of ACT-462206
Status: COMPLETED
Conditions: Safety|Tolerability|Pharmacodynamics|Pharmacokinetics
Interventions: DRUG: ACT-462206 5 mg|DRUG: ACT-462206 25 mg|DRUG: ACT-462206 100mg|DRUG: ACT-462206 200mg|DRUG: ACT-462206 400mg|DRUG: ACT-462206 1000 mg|DRUG: ACT-462206 1500mg|DRUG: Almorexant 400mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Ear Acupuncture Effectiveness In Reducing The Signs And Symptoms Of Stress And Anxiety
Status: TERMINATED
Conditions: Inclusion Criteria:|Voluntary Participation in the Study With Available Time for Submission to the Sessions, Which Occur Over Two Months.|Have a Score of Stress Medium, High or Very High in the LSS Questionnaire, Completion of the STAI and General Form.|Exclusion Criteria:|Pregnant Students.
Interventions: OTHER: Ear acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intensity-Modulated Radiation Therapy, Pemetrexed, and Erlotinib in Treating Patients With Recurrent or Second Primary Head and Neck Cancer
Status: TERMINATED
Conditions: Head and Neck Cancer
Interventions: DRUG: erlotinib hydrochloride|DRUG: pemetrexed disodium|PROCEDURE: quality-of-life assessment|RADIATION: intensity-modulated radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of TP Versus TC Regimens for Stage IVb, Persistent, or Recurrent Cervical Cancer (JCOG0505, CC-TPTC-P3)
Status: COMPLETED
Conditions: Uterine Cervical Neoplasms
Interventions: DRUG: chemotherapy: Paclitaxel/Cisplatin|DRUG: chemotherapy: Paclitaxel/Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Efficacy and Quality of Life Impact of Transitioning to Advanced Hybrid Closed-Loop Insulin Pump Therapy in Romanian Children With Type 1 Diabetes Mellitus
Status: RECRUITING
Conditions: Diabetes Mellitus, Type 1
Interventions: DEVICE: Switching to the Medtronic 780G insulin pump
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mylan Insulin Glargine Study
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: DRUG: MYL-1501D product using manufacture process V|DRUG: MYL-1501D product using manufacture process VI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility and Safety of Robotic Assisted Proximal Gastrectomy With Double-flap Technique for Proximal Early Gastric Cancer
Status: NOT_YET_RECRUITING
Conditions: Stomach Neoplasms
Interventions: PROCEDURE: Robotic assisted proximal gastrectomy with double-flap technique
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Efficacy of 2% Cyclosporine in Preventing Graft Rejection
Status: UNKNOWN
Conditions: Corneal Graft Rejection
Interventions: DRUG: Prednisolone acetate1%,|DRUG: Prednisolone acetate1%, cyclosporine 2%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Computerized Cognitive Behavioral Therapy Trial for Insomnia in Parkinson Disease
Status: COMPLETED
Conditions: Insomnia Related to Specified Disorder|Parkinson Disease
Interventions: BEHAVIORAL: CCBT-I Group|BEHAVIORAL: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Continuous Intercostal Nerve Blockade for Traumatic Rib Fractures
Status: TERMINATED
Conditions: Rib Fractures
Interventions: DRUG: hydromorphone hydrochloride|PROCEDURE: Infusion catheter placement|DRUG: bupivicaine 0.25%|DRUG: bupivicaine 0.5%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Single Doses of GSK3008348 in Idiopathic Pulmonary Fibrosis (IPF) Participants Using Positron Emission Tomography (PET) Imaging
Status: TERMINATED
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: DRUG: GSK3008348|DRUG: Placebo|DRUG: [18F]-FBA-A20FMDV2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Characterization of Bovine Adrenal Medulla as a Model of Non-histaminergic Itch
Status: COMPLETED
Conditions: Itch
Interventions: DRUG: CA and BAM8-22|DRUG: Vehicle and BAM8-22 application|DRUG: CA|DRUG: vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison Between Single Implant Retained Partial Over-denture and Conventional Partial Denture
Status: UNKNOWN
Conditions: Bone Loss in Jaw
Interventions: OTHER: Single Implant Partial Over-denture|OTHER: Conventional Partial Denture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: One Month Dose Response Study of AZD1981 in Asthma Patients Uncontrolled on Inhaled Steroids
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: AZD1981|DRUG: AZD1981|DRUG: AZD1981|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of a Tetravalent Dengue Vaccine in Healthy Adult Subjects Aged 18 to 45 Years in India
Status: COMPLETED
Conditions: Dengue|Dengue Fever|Dengue Hemorrhagic Fever
Interventions: BIOLOGICAL: Live, attenuated, recombinant dengue serotype 1, 2, 3, 4 virus|BIOLOGICAL: Placebo: NaCl 0.9% solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Hemostatic Effects of Ulinastatin and Tranexamic Acid in Cardiac Surgery
Status: COMPLETED
Conditions: Hemostasis
Interventions: DRUG: Ulinastatin|DRUG: Tranexamic Acid|DRUG: Saline Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of TPN171H Tablets in Erectile Dysfunction.
Status: COMPLETED
Conditions: Erectile Dysfunction
Interventions: DRUG: TPN171H 2.5mg group|DRUG: TPN171H 5mg group|DRUG: TPN171H 10mg group|DRUG: Placebo group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Irinotecan Liposome in Combination With 5-FU/LV Versus 5-FU/LV in Second-line Therapy for Gemcitabine-Refractory Pancreatic Cancer
Status: COMPLETED
Conditions: Second-line Treatment for Locally Advanced or Metastatic Pancreatic Cancer After Treatment Failure With Gemcitabine-based Therapy
Interventions: DRUG: Irinotecan liposome、5-Fluorouracil、Leucovorin|DRUG: Placebo、5-Fluorouracil、Leucovorin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: B-Enhancement of HBV Vaccination in Persons Living With HIV (BEe-HIVe): Evaluation of HEPLISAV-B
Status: COMPLETED
Conditions: HIV Infection|Hepatitis B
Interventions: BIOLOGICAL: HEPLISAV-B|BIOLOGICAL: ENGERIX-B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Optical Coherence Tomography Angiography (OCT-A) and Central Serous Chorioretinopathy (CSC)
Status: COMPLETED
Conditions: Central Serous Chorioretinopathy
Interventions: DEVICE: Optical Coherence Tomography Angiography (OCT-A)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: On-Q Catheter Caregiver Education
Status: COMPLETED
Conditions: Anterior Cruciate Ligament Injury|Pain; Catheter (Other)|Satisfaction, Personal
Interventions: BEHAVIORAL: Patient educaiton materials - Print based|BEHAVIORAL: Patient educaiton materials - Media based
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Clinical Trial Investigating the Short-term Relief of Symptoms of Acute Pharyngitis by Treatment With Three Different Doses of MYRAMISTIN™ Oromucosal Spray
Status: TERMINATED
Conditions: Acute Pharyngitis
Interventions: DRUG: Myramistin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Performance of the Covid-19 Ag BSS Rapid Antigenic Test in Symptomatic Children in a Pediatric Emergency Department
Status: COMPLETED
Conditions: Covid19
Interventions: DIAGNOSTIC_TEST: Performance of the test antigenic and test RT-PCR
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Piloting Mindfulness Meditation Program for Underserved Racial Minority Adults With Pulmonary Hypertension
Status: COMPLETED
Conditions: Hypertension, Pulmonary
Interventions: BEHAVIORAL: Mindfulness Meditation for Pulmonary Hypertension (MMPH)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Intratumoral Injection of Clostridium Novyi-NT Spores to Treat Patients With Solid Tumors That Have Not Responded to Standard Therapies
Status: COMPLETED
Conditions: Solid Tumor Malignancies
Interventions: BIOLOGICAL: Clostridium novyi-NT spores
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Targeting Pro-Inflammatory Cells in Idiopathic Pulmonary Fibrosis: a Human Trial
Status: COMPLETED
Conditions: Idiopathic Pulmonary Fibrosis (IPF)
Interventions: DRUG: Dasatinib + Quercetin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: An Efficacy and Safety Study of Infliximab Dose Escalation in Pediatric Participants With Inflammatory Bowel Disease
Status: TERMINATED
Conditions: Inflammatory Bowel Diseases
Interventions: DRUG: Infliximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Traditional Chinese Medicine in Management of Childhood Asthma
Status: UNKNOWN
Conditions: Asthma in Children
Interventions: OTHER: PLTG|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ganglionated Plexus Ablation For Treatment of Atrial Fibrillation
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: PROCEDURE: Image guided GP ablation|DEVICE: D-SPECT dedicated cardiac nuclear camera
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Thoracoscopic Ablation Versus Catheter Ablation in Patients With Atrial Fibrillation
Status: UNKNOWN
Conditions: Atrial Fibrillation, Persistent
Interventions: PROCEDURE: Ablation Index Guided endocardial catheter radiofrequency ablation|PROCEDURE: minimally invasive thoracoscopic surgical epicardial ablation.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 1/2 Study of TY101 for Locally Advanced /Metastatic Solid Tumors and Relapsed or Refractory Lymphomas
Status: RECRUITING
Conditions: Locally Advanced /Metastatic Solid Tumors|Relapsed or Refractory Lymphomas
Interventions: DRUG: TY101
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: COMPASSION - COngenital Multicenter Trial of Pulmonic VAlve Regurgitation Studying the SAPIEN InterventIONal THV
Status: COMPLETED
Conditions: Pulmonary Valve Insufficiency|Pulmonary Regurgitation|Dysfunctional RVOT Conduit|Pulmonary Obstruction|Pulmonary Stenosis
Interventions: DEVICE: SAPIEN Transcatheter Valve Implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non-invasive Current Stimulation for Restoration of Vision
Status: COMPLETED
Conditions: Stroke|Electrical Stimulation
Interventions: DEVICE: repetitive transorbital AC Stimulation|DEVICE: combination of transcranial direct current stimulaton and rtACS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Piloting an Internet-based Therapy for Insomnia in a Population of Veterans With Substance Use Disorders
Status: COMPLETED
Conditions: Chronic Insomnia
Interventions: BEHAVIORAL: Internet-based Cognitive Behavioral Therapy for Insomnia
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Study Evaluating the Effect of Danirixin on Neutrophil Extracellular Traps (NETs) in Chronic Obstructive Pulmonary Disease (COPD)
Status: TERMINATED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Danirixin|DRUG: Placebo|DRUG: Rescue medication|DRUG: Inhaled COPD maintenance medication
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: European Childhood Obesity Project: Early Programming by Infant Nutrition?
Status: ACTIVE_NOT_RECRUITING
Conditions: Infant Development
Interventions: DIETARY_SUPPLEMENT: Lower protein formula; Higher protein formula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Modified Dosage for Moderate Acute Malnutrition (MODAM-MAM)
Status: RECRUITING
Conditions: Moderate Acute Malnutrition
Interventions: DIETARY_SUPPLEMENT: ready-to-use supplementary food (RUSF)|DIETARY_SUPPLEMENT: ready-to-use therapeutic food (RUTF)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing the Effects of Psilocin and Psilocybin in Healthy Adults
Status: RECRUITING
Conditions: Healthy
Interventions: DRUG: Psilocin|DRUG: Psilocybin|DRUG: Sublingual Psilocin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Intermittent Fasting Accompanying Chemotherapy in Gynecological Cancers
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer|Ovarian Cancer
Interventions: OTHER: Fasting|OTHER: Vegan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Molekule for Allergic Rhinitis/Asthma
Status: TERMINATED
Conditions: Asthma|Allergic Rhinitis|Allergic Conjunctivitis
Interventions: OTHER: Active air purifier in respiratory allergies/asthma|OTHER: Sham air purifier
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: An Open-label Pilot Study of Coenzyme Q10 in Steroid-Treated Duchenne Muscular Dystrophy
Status: COMPLETED
Conditions: Muscular Dystrophy, Duchenne
Interventions: DRUG: Coenzyme Q10
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT