pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Drug-Drug Interaction Study of Rucaparib, Rosuvastatin and Oral Contraceptives
Status: COMPLETED
Conditions: Neoplasms
Interventions: DRUG: Rucaparib|DRUG: Rosuvastatin|DRUG: Oral Contraceptives
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Esophagoscopy in Evaluating Treatment in Patients With Stage I-IV Head and Neck Cancer Who Are Undergoing Radiation Therapy and/or Chemotherapy
Status: TERMINATED
Conditions: Stage I Adenoid Cystic Carcinoma of the Oral Cavity|Stage I Mucoepidermoid Carcinoma of the Oral Cavity|Stage I Squamous Cell Carcinoma of the Hypopharynx|Stage I Squamous Cell Carcinoma of the Larynx|Stage I Squamous Cell Carcinoma of the Lip and Oral Cavity|Stage I Verrucous Carcinoma of the Larynx|Stage I Verrucous Carcinoma of the Oral Cavity|Stage II Adenoid Cystic Carcinoma of the Oral Cavity|Stage II Mucoepidermoid Carcinoma of the Oral Cavity|Stage II Squamous Cell Carcinoma of the Hypopharynx|Stage II Squamous Cell Carcinoma of the Larynx|Stage II Squamous Cell Carcinoma of the Lip and Oral Cavity|Stage II Verrucous Carcinoma of the Larynx|Stage II Verrucous Carcinoma of the Oral Cavity|Stage III Adenoid Cystic Carcinoma of the Oral Cavity|Stage III Mucoepidermoid Carcinoma of the Oral Cavity|Stage III Squamous Cell Carcinoma of the Hypopharynx|Stage III Squamous Cell Carcinoma of the Larynx|Stage III Squamous Cell Carcinoma of the Lip and Oral Cavity|Stage III Verrucous Carcinoma of the Larynx|Stage III Verrucous Carcinoma of the Oral Cavity|Stage IV Adenoid Cystic Carcinoma of the Oral Cavity|Stage IV Mucoepidermoid Carcinoma of the Oral Cavity|Stage IV Squamous Cell Carcinoma of the Hypopharynx|Stage IV Squamous Cell Carcinoma of the Larynx|Stage IV Squamous Cell Carcinoma of the Lip and Oral Cavity|Stage IV Verrucous Carcinoma of the Larynx|Stage IV Verrucous Carcinoma of the Oral Cavity
Interventions: PROCEDURE: endoscopic procedure|OTHER: questionnaire administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study Evaluating Pharmacodynamics, Pharmacokinetics, Safety and Tolerability of HSK3486 Single Bolus Dose Followed With a 30 Minute Constant Infusion in Healthy Male Subjects
Status: COMPLETED
Conditions: Anesthesia|Sedation
Interventions: DRUG: HSK3486
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Chemotherapy Refractory EGFR(Epidermal Growth Factor Receptor) Positive Advanced Solid Tumors (CART-EGFR)
Status: UNKNOWN
Conditions: Advanced EGFR-positive Solid Tumors
Interventions: BIOLOGICAL: CART-EGFR
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing the Efficiency of Three Third-generation Supraglottic Airways as an Intubation Route
Status: COMPLETED
Conditions: Difficult Intubation
Interventions: DEVICE: Insertion of AirQ Blocker and intubation through the device|DEVICE: Insertion of AuraGain and intubation through the device|DEVICE: Insertion of I-Gel and intubation through the device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: IIPE-PRIS Accelerating Safe Signouts
Status: COMPLETED
Conditions: Serious Medical Errors|Resident Sign-out
Interventions: BEHAVIORAL: Resident Handoff Bundle
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Trial to Evaluate the Efficacy and Safety of Lactobacillus Plantarum DSM 33464 on Blood Lead Levels in Children
Status: COMPLETED
Conditions: Elevated Blood Lead Levels
Interventions: DIETARY_SUPPLEMENT: Lactobacillus plantarum DSM 33464|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Amino Acid Bioavailability in Healthy Elderly After Intake of an Oral Nutritional Supplement
Status: COMPLETED
Conditions: Sarcopenia
Interventions: DIETARY_SUPPLEMENT: Bolus ONS A|DIETARY_SUPPLEMENT: Bolus ONS B|DIETARY_SUPPLEMENT: Bolus ONS C|DIETARY_SUPPLEMENT: Bolus ONS D
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Palbociclib With Fulvestrant for Metastatic Breast Cancer After Treatment With Palbociclib and an Aromatase Inhibitor
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Breast Cancer
Interventions: DRUG: Palbociclib|DRUG: Fulvestrant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PanACEA Sutezolid Dose-finding and Combination Evaluation
Status: COMPLETED
Conditions: Pulmonary Tuberculosis|Other Specified Pulmonary Tuberculosis
Interventions: DRUG: Sutezolid|DRUG: Bedaquiline, Delamanid, Moxifloxacin|DRUG: Midazolam oral solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Muscle Energy Techniques and Myofascial Release on Low Back Pain Due to Sacroiliac Joint Dysfunction
Status: COMPLETED
Conditions: Sacroiliac Joint Dysfunction|Low Back Pain
Interventions: OTHER: Muscle Energy Technique|OTHER: Myofascial release
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Remote Follow-up of Patients Receiving Implantable Cardioverter Defibrillator for Prophylactic Therapy
Status: COMPLETED
Conditions: Ventricular Fibrillation|Ventricular Tachycardia
Interventions: DEVICE: Implantable Cardioverter Defibrillator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Multicenter, Randomized, Placebo-Controlled, Double-Blind Trial to Evaluate the Safety and Immunogenicity of the Therion Recombinant Vaccinia-HIV-1 IIIB ENV/GAG/POL Vaccine (TCB-3B) and MN RGP 120/HIV-1 In Alum.
Status: COMPLETED
Conditions: HIV Infections
Interventions: BIOLOGICAL: MN rgp120/HIV-1|BIOLOGICAL: TBC-3B Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Irbesartan/Hydrochlorothiazide to Control Elevated Blood Pressure to Target in Moderate to Severe Hypertensive Patients
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: irbesartan/hydrochlorothiazide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Topotecan and Cisplatin Versus Etoposide and Carboplatin in 1st Line Treatment of Patients With Small Cell Lung Cancer and Extensive Disease (SCLC-ED)
Status: TERMINATED
Conditions: Extensive Disease|First-Line|Small Cell Lung Cancer
Interventions: DRUG: topotecan + cisplatin|DRUG: Etoposide + carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Relative Bioavailability of 7 Test Tablet Formulations of JNJ-56021927 With Respect to the Capsule Formulation of JNJ-56021927 in Healthy Male Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: JNJ-56021927 capsule|DRUG: JNJ-56021927 tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Prospective Trial of Behavioral Therapy for Chronic Cough
Status: UNKNOWN
Conditions: Cough
Interventions: BEHAVIORAL: Voice Therapy|BEHAVIORAL: Voice Therapy and Heart Rate Variability Biofeedback|BEHAVIORAL: Heart Rate Variability Biofeedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: CPR Prediction After Neoadjuvant Using Excisional Biopsy By Radiofrequency In Breast Cancer From II-III UICC Stages.
Status: TERMINATED
Conditions: Triple Negative, HER2+, Luminal B Breast Tumors (Stages II-III)in Female Patients
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Development of a Mindfulness-Based Treatment for the Reduction of Alcohol Use and Smoking Cessation
Status: COMPLETED
Conditions: Tobacco Use|Alcohol Use, Unspecified
Interventions: BEHAVIORAL: Mindfulness Based Relapse Prevention - Smoking and Alcohol|BEHAVIORAL: Cognitive Behavioral Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Role of AT1-receptor Blockers in Insulin-induced Vasodilation.
Status: UNKNOWN
Conditions: Hypertension|Insulin Resistance|Microcirculation
Interventions: DRUG: Irbesartan|DRUG: Felodipine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Evaluate the Efficacy and Safety of Enlicitide Decanoate (MK-0616, Oral PCSK9 Inhibitor) Compared With Ezetimibe or Bempedoic Acid or Ezetimibe and Bempedoic Acid in Adults With Hypercholesterolemia (MK-0616-018) CORALreef AddOn
Status: RECRUITING
Conditions: Hypercholesterolemia
Interventions: DRUG: Enlicitide Decanoate|DRUG: Ezetimibe|DRUG: Bempedoic Acid|OTHER: Placebo for Enlicitide Decanoate|OTHER: Placebo for Ezetimibe|OTHER: Placebo for Bempedoic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Open Label Trial of Perifosine in Patients Currently Being Treated on Perifosine Trials in Solid Tumors or Multiple Myeloma
Status: COMPLETED
Conditions: Non Small Cell Lung Cancer|Solid Tumors|Metastatic Breast Cancer|Sarcomas
Interventions: DRUG: Perifosine|DRUG: Trastuzumab|DRUG: Tamoxifen
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Implant Survival After Insertion of Bone Level Tapered (BLT) Implant Ø 2.9 mm in the Clinical Practice Setting
Status: COMPLETED
Conditions: Tooth Loss
Interventions: DEVICE: BLT Implant Ø 2.9 mm
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effect of Liraglutide on Gastrointestinal Absorption of Several Drugs and Potential Influence of Liraglutide on Intragastric pH
Status: COMPLETED
Conditions: Diabetes|Healthy
Interventions: DRUG: liraglutide|DRUG: placebo|DRUG: atorvastatin|DRUG: lisinopril|DRUG: griseofulvin|DRUG: digoxin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: HLA-Haploidentical Peripheral Blood Stem Cell Transplantation With Post-transplant Cyclophosphamide and Bortezomib
Status: RECRUITING
Conditions: Hematological Malignancy
Interventions: DRUG: Bortezomib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Patient Education in Adherence on Acne (PEAce)
Status: COMPLETED
Conditions: Acne
Interventions: BEHAVIORAL: Standard of care + supplementary education|BEHAVIORAL: Standard of care + additional visits|BEHAVIORAL: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Evaluation of the Effects of a Mixture of Amino Acids (Amixea) on Lean Body Mass and Muscle Strengh of Patients With Unresectable Advanced Non-small Cell Lung Cancer
Status: WITHDRAWN
Conditions: Cancer Patients With Cachexia
Interventions: DIETARY_SUPPLEMENT: Amixea|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Intraprostatic Injection of Tranexamic Acid Decrease Blood Loss During Monopolar TURP
Status: NOT_YET_RECRUITING
Conditions: Benign Prostatic Hyperplasia|Transurethral Resection of the Prostate|Tranexamic Acid
Interventions: DRUG: Tranexamic Acid group|DRUG: Distilled water group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: BTL-785F Device for Non-invasive Facial Rejuvenation in Patients Injected With Botulinum Toxin
Status: COMPLETED
Conditions: Wrinkle
Interventions: DEVICE: BTL-785-7 Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adaptive Therapy With Capecitabine for the Treatment of Metastatic Estrogen Receptor Positive, HER2 Negative Breast Cancer
Status: NOT_YET_RECRUITING
Conditions: Anatomic Stage IV Breast Cancer AJCC v8|Estrogen-receptor-positive Breast Cancer|Metastatic HER2-Negative Breast Carcinoma|Metastatic Breast Cancer
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Bone Scan|DRUG: Capecitabine|PROCEDURE: Computed Tomography|PROCEDURE: Magnetic Resonance Imaging|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Patritumab Deruxtecan (U3-1402) in Unresectable Locally Advanced or Metastatic Breast Cancer
Status: RECRUITING
Conditions: Metastatic Breast Cancer
Interventions: DRUG: U3-1402
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lifei Xiaoji Wan in Treatment of Advanced NSCLC
Status: RECRUITING
Conditions: Advanced Non Small Cell Lung Cancer
Interventions: DRUG: Lifei Xiaoji Wan|OTHER: Conventional treatment with Western medicine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Mephedrone and Alcohol Interactions in Humans
Status: COMPLETED
Conditions: Amphetamine-Related Disorders|Alcohol-Related Disorders
Interventions: DRUG: Mephedrone and alcohol|DRUG: Mephedrone|DRUG: Alcohol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Role of Epoxyeicosatrienoic Acids in Chronic Allograft Nephropathy - The TRANSPLANT-EETs Study
Status: COMPLETED
Conditions: Kidney Transplant Recipients
Interventions: PROCEDURE: Blood sampling|PROCEDURE: flow-mediated distal stimulation of the forearm radial artery by cutaneous heating
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Efficacy Study of Sorafenib and Cyclophosphamide to Treat Neuroendocrine Tumors
Status: COMPLETED
Conditions: Neuroendocrine Tumors
Interventions: DRUG: Sorafenib|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Interferon Alfa-2b With or Without Thalidomide in Treating Patients With Metastatic or Unresectable Kidney Cancer
Status: COMPLETED
Conditions: Kidney Cancer
Interventions: BIOLOGICAL: recombinant interferon alfa|DRUG: thalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: The Effect of Soft Tissue Mobilization and Kinesio Taping Applied to Athletics Athletes on Sports Performance
Status: COMPLETED
Conditions: Athletic Injuries|Sports Physical Therapy
Interventions: OTHER: taping|OTHER: Control|OTHER: mobilization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Safety and Efficacy Study of the Dynalink®-E Everolimus Eluting Peripheral Stent System
Status: COMPLETED
Conditions: Atherosclerosis|Peripheral Vascular Disease
Interventions: DEVICE: Dynalink®-E everolimus-eluting peripheral stent|DEVICE: Dynalink®-E, everolimus-eluting peripheral stent
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of A Collagen Bupivacaine Implant in Patients After Gastrointestinal Surgery
Status: TERMINATED
Conditions: Pain, Postoperative
Interventions: DRUG: Bupivacaine Collagen Sponge|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Adding Small Amounts of Oxygen to the CO2 Pneumoperitoneum Upon Pain and Inflammation
Status: COMPLETED
Conditions: Pain|Inflammation
Interventions: PROCEDURE: addition of 4% oxygen|PROCEDURE: carbon dioxde
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy of Ziprasidone in Children and Adolescents With Bipolar I Disorder (Manic or Mixed)
Status: COMPLETED
Conditions: Bipolar Disorder
Interventions: DRUG: Ziprasidone oral capsules|DRUG: placebo oral capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Conversion of ENcapsulated GlucorAphanin, Gut Microbiota Phylogeny and gEnotype Study (ENGAGE)
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: 100mg glucoraphanin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Oncoplastic Partial Mastectomy With Intraoperative Radiation Therapy (IORT) in Early Stage Breast Cancer Patients With Prior History of Chest Wall Radiation.
Status: RECRUITING
Conditions: IORT-Intra-Operative Radiation Therapy
Interventions: RADIATION: Intraoperative Radiotherapy|PROCEDURE: Oncoplastic partial mastectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Face Your Fears: Cognitive Behavioural Virtual Reality Therapy for "Paranoia".
Status: ACTIVE_NOT_RECRUITING
Conditions: Paranoid Schizophrenia|Schizophrenia and Related Disorders|Schizophrenia Prodromal|Schizotypal Disorder|Paranoid Ideation|Paranoid Delusion|Ideas of Reference|Psychosis Paranoid|Psychotic Disorders|Psychotic Paranoia|Psychotic; Disorder, Delusional
Interventions: OTHER: Cognitive Behavioural Virtual Reality Therapy.|OTHER: Traditional Cognitive Behavioural Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Anti-PD-L1 Antibody in Neoadjuvant Chemotherapy of Esophageal Squamous Cell Carcinoma.
Status: UNKNOWN
Conditions: Esophageal Cancer
Interventions: DRUG: anti-PD-L1 antibody|DRUG: albumin bound paclitaxel|DRUG: cisplatin|DRUG: placebo|PROCEDURE: radical resection of esophageal carcinoma
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Mesh Fixation With Tissue Adhesive
Status: RECRUITING
Conditions: Groin Hernia|Hernia, Inguinal|Postoperative Pain|Neuropathic Pain
Interventions: DEVICE: Use of n-hexyl cyanoacrylate for mesh fixation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lipoarabinomannan (LAM) in Urine for Diagnosis of Pulmonary Tuberculosis in HIV Patients
Status: COMPLETED
Conditions: TB - Tuberculosis HIV
Interventions: DIAGNOSTIC_TEST: Urinary LAM ELISA:
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study to Evaluate the Efficacy and Safety of DS-1971a for the Treatment of Diabetic Peripheral Neuropathic Pain (DPNP)
Status: WITHDRAWN
Conditions: Neuropathic Pain|Diabetes
Interventions: DRUG: DS-1971a|DRUG: placebo|DRUG: pregabalin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Corticospinal Excitability and Rehab in Knee Osteoarthritis
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: OTHER: Transcutaneous Electrical Nerve Stimulation|OTHER: Physical Therapy Exercises|OTHER: No Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Agreement and Accuracy of Different Devices Corneal Measurements
Status: COMPLETED
Conditions: Keratoconus
Interventions: DEVICE: Pentacam® (Oculus, Inc., Wetzlar, Germany)|DEVICE: Casia II (Tomey Germany, Nürnberg)|DEVICE: Spectralis Anterion (Heidelberg Engineering, Heidelberg, Germany)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Combined Use of a Respiratory Broad Panel Multiplex PCR and Procalcitonin to Reduce Antibiotics Exposure in Hospitalized Sickle-cell Adults With Acute Chest Syndrome.
Status: COMPLETED
Conditions: Acute Chest Syndrome|Sickle Cell Disease
Interventions: PROCEDURE: Intervention: Combined use of a respiratory broad panel multiplex PCR and procalcitonin|PROCEDURE: Control: usual antibiotic treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Antimicrobial Stewardship Intervention in Hospitalized COVID-19 Patients (COVASP)
Status: COMPLETED
Conditions: Covid19|COVID-19 Pneumonia|COVID-19 Lower Respiratory Infection|COVID-19 Acute Respiratory Distress Syndrome|SARS-CoV2 Infection|SARS-CoV-2 Acute Respiratory Disease
Interventions: BEHAVIORAL: Antimicrobial stewardship prospective audit and feedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study to Determine Safety and Efficacy of B244 in Subjects With Mild to Moderate Rosacea
Status: COMPLETED
Conditions: Rosacea
Interventions: BIOLOGICAL: B244|BIOLOGICAL: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Management of Pleural Space Infections
Status: COMPLETED
Conditions: Empyema, Pleural|Parapneumonic Effusion
Interventions: DRUG: Intrapleural Medications|PROCEDURE: Surgery|PROCEDURE: Pleural Sampling|PROCEDURE: Pleural fluid drainage|RADIATION: Protocol Image #1|OTHER: Surgical Consultation|RADIATION: Protocol Image #2: Chest X-ray PA/Lateral|BEHAVIORAL: Quality of Life
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sutures Versus Glue in Laparoscopic Port Site Closure.
Status: UNKNOWN
Conditions: Cosmetic Outcome|Infection|Cost
Interventions: OTHER: 4-0 Monocryl|OTHER: Adhesive Glue
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Targeted or Chemotherapy Combined With Immunotherapy Versus Chemotherapy for PD-1 Inhibitor Refractory R/M NPC
Status: RECRUITING
Conditions: Nasopharyngeal Carcinoma
Interventions: DRUG: Apatinib, Camrelizumab, Chemotherapy (gemcitabine/ capecitabine/ docetaxel)|DRUG: Apatinib, Camrelizumab|DRUG: Camrelizumab, Chemotherapy (gemcitabine/ capecitabine/ docetaxel)|DRUG: Chemotherapy (gemcitabine/ capecitabine/ docetaxel)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Niacin/Laropiprant Tablet for South and Southeast Asians With Low High-Density Lipoprotein Cholesterol (LDL-C) at Risk for Cardiovascular Disease (MK-0524A-108)
Status: TERMINATED
Conditions: Dyslipidemia
Interventions: DRUG: ERN/LRPT|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Peri-Procedural Transmural Electrophysiological (EP) Imaging of Scar-Related Ventricular Tachycardia
Status: RECRUITING
Conditions: Ventricular Tachycardia|Myocardial Infarction
Interventions: DIAGNOSTIC_TEST: EP Imaging and Testing
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Research on Gut Microbiome and Metabolomics Alterations in C.Difficile Infected IBD Patients
Status: RECRUITING
Conditions: Inflammatory Bowel Diseases|Clostridium Difficile Infections|Microtia
Interventions: DIAGNOSTIC_TEST: Clostridioides difficile toxin detection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Respiratory Muscle Training in Patients With Spinal Muscular Atrophy (SMA).
Status: ACTIVE_NOT_RECRUITING
Conditions: Spinal Muscular Atrophy
Interventions: OTHER: Inspiratory and expiratory muscle training at a therapeutic intensity|OTHER: Inspiratory and expiratory muscle training at a non-therapeutic intensity
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Pembrolizumab Plus Epacadostat With Platinum-based Chemotherapy Versus Pembrolizumab Plus Platinum-based Chemotherapy Plus Placebo in Metastatic Non-Small Cell Lung Cancer (KEYNOTE-715-06/ECHO-306-06)
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DRUG: Pembrolizumab|DRUG: Epacadostat|DRUG: Platinum-based chemotherapy|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of C3F8 or SF6 Use and Length of Face-down Positioning (7 vs 14 Days Respectively) in Macular Hole Surgery
Status: COMPLETED
Conditions: Macular Holes|Visual Acuity Gain|Cataract|Complications
Interventions: PROCEDURE: Macular hole surgery using a 25 G pars plana vitrectomy, ILM peeling, fluid-air exchange followed by air-gas exchange with SF6 or C3F8.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Roflumilast and Cognition
Status: COMPLETED
Conditions: Dementia
Interventions: DRUG: roflumilast (EU: Daxas, USA: Daliresp)|DRUG: Placebo|DRUG: roflumilast
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of Postoperative QoR-15 Scores Between Desflurane and Remimazolam in Lumbar Fusion Surgery
Status: COMPLETED
Conditions: Lumbar Fusion Surgery
Interventions: DRUG: Desﬂurane|DRUG: Remimazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Cutting Balloon Versus Non-cutting Balloon for the Treatment of Venous Stenosis in the Fistulas of Hemodialyzed Patients
Status: TERMINATED
Conditions: Arteriovenous Fistula|Fistula
Interventions: PROCEDURE: Cutting balloon angioplasty|PROCEDURE: Angioplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Assessing Injection Pain of Makena® (Hydroxyprogesterone Caproate Injection, 250 mg/mL) When Administered Via Subcutaneous Auto-injector vs Intramuscular Injection Via Needle and Syringe in Healthy Post-menopausal Women
Status: TERMINATED
Conditions: Assessing Injection Pain of Makena® (Hydroxyprogesterone Caproate Injection, 250 mg/mL) in Healthy Post-menopausal Women
Interventions: DRUG: Makena® (Hydroxyprogesterone Caproate Injection, 250 mg/mL)|DRUG: Makena® (Hydroxyprogesterone Caproate Injection, 250 mg/mL)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: COVID-19: A POC Test Under Research & Evaluation
Status: SUSPENDED
Conditions: COVID-19
Interventions: DIAGNOSTIC_TEST: Sample Collection/Performance Evaluation (A)|DIAGNOSTIC_TEST: Sample Collection/Performance Evaluation (B)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Serum TRAP-5b Levels in Patients With Generalized Chronic Periodontitis
Status: COMPLETED
Conditions: Chronic Periodontitis
Interventions: PROCEDURE: Scaling and root planing|DRUG: scaling and root planing along with antibiotic intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial to Assess the Effect of Delgocitinib Cream 20 mg/g on the Molecular Signature, Safety, and Efficacy in Adults With Frontal Fibrosing Alopecia
Status: COMPLETED
Conditions: Frontal Fibrosing Alopecia
Interventions: DRUG: Delgocitinib cream|DRUG: Delgocitinib cream vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Intratumoral (IT) Ulevostinag (MK-1454) in Combination With Intravenous (IV) Pembrolizumab (MK-3475) Compared to IV Pembrolizumab Alone as the First Line Treatment of Metastatic or Unresectable, Recurrent Head and Neck Squamous Cell Carcinoma (HNSCC) (MK-1454-002)
Status: COMPLETED
Conditions: Head and Neck Squamous Cell Carcinoma (HNSCC)
Interventions: DRUG: Ulevostinag|BIOLOGICAL: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Substrate Utilization, Exercise Performance, and Skeletal Muscle Response to Energy Deficit and Altitude Acclimatization
Status: COMPLETED
Conditions: Weight Loss|Other Effects of High Altitude
Interventions: OTHER: Standard pro|OTHER: High pro|OTHER: carbo bev|OTHER: placebo bev
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Pulpectomy of Primary Molars With Rotary Instrumentation Versus Manual Instrumentation
Status: UNKNOWN
Conditions: Chronic|Infection
Interventions: DEVICE: Rotary instrumentation|DEVICE: Hand instrumentation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Forgiveness-Based Writing to Prevent Post-Traumatic Stress Disorder (PTSD) in Operation Enduring Freedom/Operation Iraqi Freedom (OEF/OIF) Veterans
Status: UNKNOWN
Conditions: Stress Disorders, Traumatic|Anxiety Disorders|PTSD
Interventions: BEHAVIORAL: Forgiveness-Based Writing
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of Calcitriol BID Topical Treatment in Adolescents With Plaque Psoriasis
Status: COMPLETED
Conditions: Chronic Plaque Psoriasis
Interventions: DRUG: Calcitriol 3mcg/g
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing the Response of Patients With Hypertension to Amlodipine or Amlodipine Plus Benazepril.
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: amlodipine/benazepril
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Forehead Scars Following Mohs Micrographic Surgery and Reconstruction for Skin Cancer
Status: TERMINATED
Conditions: Scar
Interventions: DRUG: Dysport (abobotulinumtoxinA)|DRUG: Bacteriostatic 0.9% Sodium Chloride (vehicle)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Tailored Smoking Cessation Treatment Algorithm Based on Initial Treatment Response and Genotype
Status: COMPLETED
Conditions: Smoking Cessation
Interventions: DRUG: Nicotine Patches|DRUG: Nicotine patches, then bupropion & nicotine patches (Pre-Quit)|DRUG: Nicotine patches, then varenicline (Pre-Quit)|DRUG: Nicotine patches, then nicotine patches (Pre-Quit)|DRUG: Nicotine patches, then bupropion & nicotine patches (Post-Quit)|DRUG: Nicotine patches, then varenicline (Post-Quit)|DRUG: Nicotine patches, then nicotine patches (Post-Quit)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Epinephrine and Exercise Test in QT Long Syndrome Patients
Status: UNKNOWN
Conditions: Long QT Syndrome Type 1 or 2
Interventions: OTHER: exercise test|OTHER: Epinephrine test
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: ¡Salud! Por la Vida (SPLV) A Colorectal Screening Promotion Program
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: BEHAVIORAL: ¡Salud! Por la Vida
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Dairy Lipids and Cardiometabolic Risk
Status: RECRUITING
Conditions: Morbid Obesity
Interventions: OTHER: Low-fat dairy products|OTHER: Whole-fat dairy products|OTHER: Milk polar lipid enriched whole-fat dairy products
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Effect of Pre-operative Videotape Before a Planned Cesarean Section on Anxiety Level
Status: RECRUITING
Conditions: Anxiety|Cesarean Section Complications|Pain, Postoperative|Analgesia
Interventions: BEHAVIORAL: pre-prepared video describing the cesarean surgery|BEHAVIORAL: general information
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of the Efficacy and Safety of Bupivacaine TTS Patch in Patients With Chronic Low Back Pain
Status: COMPLETED
Conditions: Chronic Low Back Pain
Interventions: DRUG: Bupivacaine TTS (Bupivacaine Patch)|DRUG: Placebo patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Characteristics and Risk Factors of Children Suffering From Inflammatory Bowel Diseases At Assiut University Children Hospital
Status: RECRUITING
Conditions: Inflammatory Bowel Disease
Interventions: OTHER: labortatory such as fecal calprotectin ,CRP,CBC,ESR. Endoscopic examination of the gastrointestinal tract Histological examination of the biopsies retrieved during gastrointestinal endoscope.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Video Training on Symptom Burden Patients Undergoing Hemodialysis Treatment
Status: COMPLETED
Conditions: Symptom Cluster|Quality of Life|Conformity, Social
Interventions: OTHER: Visual video education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Narrative Exposure Therapy (NET) for Victims of the Recent Flood Disaster in Burundi
Status: COMPLETED
Conditions: Posttraumatic Stress Disorder
Interventions: BEHAVIORAL: Narrative Exposure Therapy (NET)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Single and Double Operator Techniques in Ultrasound-guided Peripheral Nerve Block Learning Curve
Status: UNKNOWN
Conditions: Single-handed Ultrasound-guided Regional Anaesthesia Grip|Single-operator Ultrasound-guided Peripheric Nerve Block|Anesthesiology Training|Jedi Grip
Interventions: OTHER: reaching targeted area on the phantom model
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Assessment of a Robotic Exoskeleton for Upper Limb Rehabilitation
Status: NOT_YET_RECRUITING
Conditions: Spinal Cord Injuries
Interventions: DEVICE: Experimental: Device Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Long-term Effectiveness and Immuno-persistence Study of a Recombinant HPV 16/18 Bivalent Vaccine in Preadolescent Girls
Status: NOT_YET_RECRUITING
Conditions: Cervical Intraepithelial Neoplasia|Cervical Cancer|Persistent Infection
Interventions: BIOLOGICAL: Recombinant Human Papillomavirus Bivalent (Types 16, 18) Vaccine (Escherichia coli)|OTHER: No intervention|BIOLOGICAL: Recombinant Human Papillomavirus Bivalent (Types 16, 18) Vaccine (Escherichia coli)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Magnetic Resonance Imaging for Cerebral Embolization During Minimal Invasive Mitral Valve Surgery
Status: UNKNOWN
Conditions: Neurological Complications|Mitral Valve Insufficiency
Interventions: PROCEDURE: Mitral valve surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: An Intervention-Based Approach to Strengthen the Psychological Health of Children With Cystic Fibrosis and Their Mothers
Status: RECRUITING
Conditions: Cystic Fibrosis|Children|Resilience,Psychological|Laughter Yoga|Laughter Therapy|Mothers|Psychological Health|Lung Functions
Interventions: OTHER: Intervention Program Based on Strengthening the Psychological Resilience of Children Diagnosed with Cystic Fibrosis and Their Mothers
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: SHERLOCK 3CG™ Diamond Tip Confirmation System
Status: TERMINATED
Conditions: Indication for Peripheral Intravenous Catheterization|Atrial Flutter|Premature Atrial Contraction|Premature Ventricular Contraction|Premature Junctional Contraction|Tachycardia|Atrioventricular Block|Bundle-Branch Block
Interventions: PROCEDURE: PICC placement with SHERLOCK 3CG™ Diamond TCS with MODUS II software
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety Study of Bromfenac Ophthalmic Solution in Subjects With Diffuse Diabetic Macular Edema (DME) Refractory to Laser
Status: UNKNOWN
Conditions: Diabetic Macular Edema
Interventions: DRUG: Bromfenac ophthalmic solution
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Icotinib With Concurrent Radiotherapy vs. Chemoradiotherapy in Non-small Cell Lung Cancer
Status: UNKNOWN
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: Icotinib|DRUG: Pemetrexed|DRUG: Carboplatin|RADIATION: Thoracic radiotherapy(TRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cardiac MRI Biomarker Testing (GCC 1618)
Status: TERMINATED
Conditions: Breast Cancer|Lung Cancer (Non-Small Cell)|Thoracic Cancer|Thymic Cancer|Mesothelioma
Interventions: OTHER: Complete Cardiac Magnetic Resonance Imaging (MRI)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Ultrasound Evaluation of the IVC in Addition to Clinical Assessment to Guide Decongestion in ADHF
Status: COMPLETED
Conditions: Heart Failure
Interventions: DIAGNOSTIC_TEST: Ultrasound evaluation of the inferior vena cava diameter|DIAGNOSTIC_TEST: Sham ultrasound evaluation of the inferior vena cava diameter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of Electroacupuncture in Axial Spondyloarthritis (E-AcuSpA)
Status: RECRUITING
Conditions: Spondylarthritis|Axial Spondyloarthritis
Interventions: OTHER: Electroacupuncture|OTHER: Manual acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Two Formulatiosns With the Asscociaton of Efavirenz, Emtricitabine and Tenofovir
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Efavirenz, tenofovir disoproxil fumarate and emtricitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study to Evaluate the Efficacy and Safety of BMN 111 in Children With Achondroplasia
Status: COMPLETED
Conditions: Achondroplasia
Interventions: DRUG: BMN 111|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Hysterectomy After Chemoradiation Therapy for Stage IB2/II Cervical Cancer
Status: TERMINATED
Conditions: Stage IB2 Cervical Cancer|Stage II Cervical Cancer|Adenocarcinoma|Squamous Cell Carcinoma|Adenosquamous Carcinoma
Interventions: PROCEDURE: hysterectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preoxygenation With Positive Inspiratory Pressure During Induction of Anesthesia
Status: COMPLETED
Conditions: Anesthesia
Interventions: OTHER: PPV : positive pressure ventilation|OTHER: PEEP : PPV + PEEP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of Subcutaneous and Intravenous VELCADE in Patients With Previously Treated Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: VELCADE Administered by subcutaneous injection|DRUG: VELCADE Administered by intravenous infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: In Vivo Investigation of Initial Stages of Enamel Erosion
Status: COMPLETED
Conditions: Tooth Erosion
Interventions: OTHER: Sodium fluoride + potassium nitrate|OTHER: Potassium nitrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of the Effectiveness of Treatment With Mifepristone and Misoprostol at the Same Time Compared to the Administration of Drugs at a 48-hour Interval for Medical Abortion.
Status: ACTIVE_NOT_RECRUITING
Conditions: Early Pregnancy
Interventions: DRUG: Administration of drugs concomitantly.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vaccine Therapy in Treating Patients With Stage III or Stage IV Melanoma That Cannot Be Removed With Surgery
Status: UNKNOWN
Conditions: Melanoma (Skin)
Interventions: BIOLOGICAL: D1/3-MAGE-3-His fusion protein|BIOLOGICAL: SB-AS02B adjuvant|BIOLOGICAL: SB-AS15 adjuvant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open Versus Laparoscopic Ablation of Liver Malignancies
Status: RECRUITING
Conditions: Hepatocellular Carcinoma|Cholangiocarcinoma|Liver Metastases
Interventions: PROCEDURE: Laparoscopic ablation|PROCEDURE: Open ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Community Study of Outcome Monitoring for Emotional Disorders in Teens
Status: COMPLETED
Conditions: Depression|Anxiety
Interventions: BEHAVIORAL: Unified Protocol for Adolescents (UP-A)|BEHAVIORAL: Youth Outcomes Questionnaire|BEHAVIORAL: Treatment as Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of a 0.03% CHX Mouth Rinse in Peri-implant Mucositis
Status: COMPLETED
Conditions: Peri-implant Mucositis
Interventions: OTHER: Chlorhexidine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Goal-directed Fluid Therapy Using Stroke Volume Variation in Patients Undergoing Free Flap Reconstruction After Head and Neck Cancer Resection
Status: COMPLETED
Conditions: General Anesthesia
Interventions: PROCEDURE: Standard fluid therapy|PROCEDURE: Conservative fluid therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Efficacy of Adding Intraluminal Brachytherapy After CCRT for Local-regional Thoracic Esophageal Cancer.
Status: RECRUITING
Conditions: Esophageal Neoplasms|Head and Neck Neoplasms|Gastrointestinal Neoplasms|Digestive System Diseases|Digestive System Neoplasms|Esophageal Diseases|Neoplasms by Site|Gastrointestinal Diseases|Neoplasms
Interventions: DEVICE: "BRAXX" Esophageal Brachytherapy Applicator.|RADIATION: Add-on of intraluminal brachytherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT