pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Clinical Evaluation of SDF Combined With KI Versus SDF in Management of Class I Carious Lesions
Status: UNKNOWN
Conditions: Carious Lesion
Interventions: OTHER: Silver Diamine Fluoride combined with Potassium Iodide.|OTHER: Silver Diamine Fluoride.|OTHER: High-Viscosity Glass Ionomer.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Open Chain Kinetic Exercises and Forward Head Posture Correction in Type II Scapular Dyskinesia
Status: COMPLETED
Conditions: Dyskinesias
Interventions: OTHER: Open chain kinetic exercises|OTHER: Forward head posture correction exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Efficacy of a Silk-Like Fabric for the Prevention of Pressure Sores in a Long Term Care Setting
Status: COMPLETED
Conditions: Pressure Ulcers
Interventions: DEVICE: DermaTherapy® Linen and underpads.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Digital and Behavioral Tele-Health Tapering Program for Lowering Dependence on Opioids in Patients Undergoing Surgery
Status: UNKNOWN
Conditions: Malignant Abdominal Neoplasm|Malignant Head and Neck Neoplasm|Malignant Solid Neoplasm|Malignant Thoracic Neoplasm
Interventions: BEHAVIORAL: Behavioral Intervention|OTHER: Best Practice|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of Methods of Self-regulation of Mental State on Pain Perception in the Postoperative Period in Colon Cancer Patients
Status: RECRUITING
Conditions: Colonic Neoplasms|Pain, Postoperative|Hypnotherapy
Interventions: BEHAVIORAL: Autohypnosis|BEHAVIORAL: Relaxing music
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Early Intervention Coping Kids (TIM) Follow up Study
Status: NOT_YET_RECRUITING
Conditions: Anxiety Disorders|Depression
Interventions: OTHER: EMOTION Kids coping with anxiety and depression (Kendall et. al, 2013) (Mestrende barn in Norwegian) Martinsen et al, 2014
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: On Demand Antiretroviral Pre-exposure Prophylaxis for HIV Infection in Men Who Have Sex With Men
Status: COMPLETED
Conditions: HIV Infection
Interventions: DRUG: Truvada|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Impact of FBB PET Amyloid Imaging in Change of Diagnosis in Patients With AD
Status: COMPLETED
Conditions: Alzheimer's Disease (AD)
Interventions: DRUG: Neuraceq (florbetaben 18F)|PROCEDURE: PET
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Clinical Phase II Clinical Study Evaluating the Toxicity and Efficacy of mFOLFIRINOX Associated With SBRT (Stereotactic Radiotherapy) in Patients With Unresectable Locally Advanced Pancreatic Cancer
Status: COMPLETED
Conditions: Cancer of Pancreas|Unresectable Pancreatic Cancer|Chemotherapy Effect|SBRT
Interventions: DRUG: Patients will receive initial chemotherapy, followed by evaluation of the response to the treatment, followed by SBRT, followed by chemotherapy.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Prevalence, Risk Factors and Optimal Biopsy Protocol of BE
Status: RECRUITING
Conditions: Barrett's Esophagus|Intestinal Metaplasia
Interventions: PROCEDURE: One biopsy|PROCEDURE: Three biopsy|PROCEDURE: Seattle protocol|DEVICE: Endoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: S9832: Effectiveness of Telephone Counseling By Breast Cancer Survivors on the Well-Being of Women With Recurrent Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer|Psychosocial Effects of Cancer and Its Treatment
Interventions: PROCEDURE: psychosocial assessment and care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Phase 2 Platform Study in Patients With Advanced Non-Small Lung Cancer Who Progressed on First-Line Osimertinib Therapy (ORCHARD)
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: Osimertinib|DRUG: Savolitinib|DRUG: Gefitinib|DRUG: Necitumumab|DRUG: Durvalumab|DRUG: Carboplatin|DRUG: Pemetrexed|DRUG: Alectinib|DRUG: Selpercatinib|DRUG: Selumetinib|DRUG: Etoposide|DRUG: Cisplatin|DRUG: Datopotamab deruxtecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Analgesia After Total Hip Arthroplasty: Peri-Articular Injection Versus Epidural Patient Controlled Analgesia (PCA)
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: PROCEDURE: Peri-Articular Injection|PROCEDURE: Epidural Patient Controlled Analgesia (Epidural PCA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Effect and Safety of Autologous Umbilical Cord Blood Transfusion in the Treatment of Cerebral Palsy
Status: UNKNOWN
Conditions: Safety Issues|Effect of Drugs
Interventions: DRUG: 0.9% Sodium Chloride|BIOLOGICAL: Autologous Umbilical Cord Blood
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dexmedetomidine Facilitate Analgesia
Status: COMPLETED
Conditions: Lower Limb Fracture|Nerve Block
Interventions: DRUG: Dexmedetomidine|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Subtotal Parathyroidectomy or Total Parathyroidectomy With Autograft in Chronic Kidney Disease Patients Under Dialysis
Status: ACTIVE_NOT_RECRUITING
Conditions: Hyperparathyroidism, Secondary
Interventions: PROCEDURE: Subtotal Parathyroidectomy|PROCEDURE: Total Parathyroidectomy + 45 autografts|PROCEDURE: Total Parathyroidectomy + 90 autografts
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimal Duration of Antiplatelet Therapy After Bioresorbable Vascular Scaffold Implantation to Reduce Late Coronary Arterial Thrombotic Events
Status: COMPLETED
Conditions: Percutaneous Transluminal Coronary Angioplasty|Coronary Disease
Interventions: DRUG: aspirin and clopidogrel|DRUG: Clopidogrel only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cetuximab+mFOLFOX6 VS. mFOLFOX6 Alone in RAS/BRAF Wild Type Patients With High-Risk Resectable CRLM
Status: NOT_YET_RECRUITING
Conditions: Colorectal Cancer|Liver Metastases
Interventions: DRUG: mFOLFOX6 + Cetuximab|DRUG: mFOLFOX 6
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase III Double-blind, Placebo-controlled Study of AZD7442 for Post- Exposure Prophylaxis of COVID-19 in Adults
Status: COMPLETED
Conditions: COVID-19
Interventions: DRUG: AZD7442|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Efficacy and Safety of Brolucizumab vs. Aflibercept in Chinese Patients With Neovascular Age-Related Macular Degeneration
Status: COMPLETED
Conditions: Neovascular Age-Related Macular Degeneration
Interventions: DRUG: Brolucizumab 6mg|DRUG: Aflibercept 2 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Upper-limb Active Function and Botulinum Toxin A
Status: RECRUITING
Conditions: Stroke|Muscle Spasticity|Upper Extremity Paralysis
Interventions: OTHER: Clinical evaluation|OTHER: Clinical evaluation and Instrumental evaluation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluating the Pharmacokinetics and Drug Interaction Potential of the Botanical Dietary Supplement Cinnamon
Status: ACTIVE_NOT_RECRUITING
Conditions: Interaction Drug Food
Interventions: DIETARY_SUPPLEMENT: Cinnamon (2 g)|DRUG: Nicotine gum (2.5 mg)|DRUG: Letrozole (2.5 mg)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Acute Intermittent Hypoxia on Sensory Function in Healthy Adults
Status: COMPLETED
Conditions: Sensitivity
Interventions: DEVICE: Intervention 1|DEVICE: Intervention 2|DEVICE: Intervention 3|DEVICE: Intervention 4 (sham)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Efficacy of Combined Ibuprofen and Acetaminophen Therapy Versus Ibuprofen Alone Versus Placebo Alone for Pain Management
Status: RECRUITING
Conditions: Pain, Orofacial
Interventions: DRUG: Ibuprofen 200 mg and acetaminphen 650 mg|DRUG: Ibuprofen 200 mg|DRUG: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of the PAINLESS Nerve Growth Factor CHF6467 in Optic Pathway Glioma (OPG)
Status: RECRUITING
Conditions: Optic Pathway Glioma
Interventions: DRUG: CHF6467|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 3 Extension Study to Evaluate Long-term Safety of Ianalumab in Participants With Systemic Lupus Erythematosus (SIRIUS-SLE Extension).
Status: RECRUITING
Conditions: Systemic Lupus Erythematosus
Interventions: DRUG: Placebo|DRUG: Ianalumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Renal Stenting With Distal Atheroembolic Protection
Status: UNKNOWN
Conditions: Renal Artery Obstruction|Renovascular Hypertension
Interventions: PROCEDURE: Percutaneous renal stenting intervention|DEVICE: Distal embolic protection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A New Generation of Magnetoencephalographs for High Speed Functional Brain Imaging
Status: NOT_YET_RECRUITING
Conditions: Mild Concussion|Healthy Volunteers
Interventions: DEVICE: Experiment 1: visual and auditory attention task|DEVICE: Experiment 2: language production and rest tasks|DEVICE: Experiment 3: visuo-motor task|DEVICE: Experiment 4: brain activity at rest
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Bioavailability of Prochlorperazine Suppositories, 25 mg
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Prochlorperazine suppositories, 25mg|DRUG: Compazine® suppositories, 25mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Electromechanically Optimised Right Ventricular Pacing In Hypertrophic Cardiomyopathy (EMORI-HCM)
Status: RECRUITING
Conditions: Hypertrophic Cardiomyopathy|Hypertrophic Obstructive Cardiomyopathy
Interventions: DEVICE: AV Delay Optimised RV Pacing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ozonated Olive Oil in Treatment of Pemphigus Vulgaris and Bullous Pemphigoid
Status: RECRUITING
Conditions: Pemphigus Vulgaris|Bullous Pemphigoid
Interventions: DRUG: Ozonated olive oil|DRUG: Topical garamycin cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Nonmotor Symptomatology of Parkinsonian Patients Treated With Two Strategies Related to Apomorphine Pump Therapy in French Hospitals
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: DRUG: Apomorphine|DRUG: Dopaminergic Agonist + Apomorphine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Meridian Activation Remedy System for Parkinson's Disease
Status: RECRUITING
Conditions: Parkinson Disease
Interventions: OTHER: Meridian Activation Remedy System for Parkinson's Disease (MARS-PD)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Frequency of Ventilator-Associated Pneumonia in Intubated Patients Followed Up With Automatic Cuff Pressure Controller and Manual Cuff Pressure Controller in Pediatric Intensive Care
Status: RECRUITING
Conditions: Ventilator-associated Pneumonia
Interventions: DEVICE: endotracheal cuff pressure manual measurement|DEVICE: endotracheal cuff pressure automatic measurement
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Tolerability, Pharmacokinetics and Efficacy of ZSP1603 in Patients With Idiopathic Pulmonary Fibrosis （IPF）
Status: RECRUITING
Conditions: Idiopathic Pulmonary Fibrosis (IPF)
Interventions: DRUG: ZSP1603|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Avelumab in Patients With MSS, MSI-H and POLE-mutated Recurrent or Persistent Endometrial Cancer and of Avelumab/Talazoparib and Avelumab/Axitinib in Patients With MSS Recurrent or Persistent Endometrial Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Endometrial Cancer
Interventions: DRUG: Avelumab|DRUG: Talazoparib|DRUG: Axitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EFFECT OF CT GUIDED MOBILIZATION ON CERVICAL FOREMAN'S DIMENSIONS
Status: RECRUITING
Conditions: EFFECT OF CT Guided Mobilization ON CERVICAL RADICULOPATHY
Interventions: OTHER: CT guided opening mobilization of cervical intervertebral foreman
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CALM IVF (Creating Affiliations, Learning, and Mindfulness for In Vitro Fertilization Patients)
Status: UNKNOWN
Conditions: Quality of Life|IVF|Patient Satisfaction|Patient Engagement|Patient Empowerment
Interventions: BEHAVIORAL: CALM IVF|OTHER: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Enterprise Stent Implantation in the Treatment of Carotid Artery Stenosis With Ischemic Stroke
Status: COMPLETED
Conditions: Carotid Artery Stenosis
Interventions: DEVICE: Enterprise stent implantation|DRUG: Only aspirin medication
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Verify if the Surgery for the Proximal Femur Fracture Can be Improved With the Help of a Navigation System
Status: RECRUITING
Conditions: Femoral Fracture
Interventions: PROCEDURE: Intramedullary nailing with ADAPT system|PROCEDURE: Intramedullary nailing without ADAPT system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Diabetes Prevention Program With or Without Hunger Training in Helping to Lower Breast Cancer Risk in Obese Participants
Status: ACTIVE_NOT_RECRUITING
Conditions: Deleterious BRCA1 Gene Mutation|Deleterious BRCA2 Gene Mutation|Ductal Breast Carcinoma In Situ|Obesity|Overweight|Premalignant Lesion
Interventions: OTHER: Behavioral, Psychological or Informational Intervention|OTHER: Behavioral, Psychological or Informational Intervention|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Impact of Alternative Treatment Strategies and Delivery Systems for Soil-transmitted Helminths in Kenya
Status: COMPLETED
Conditions: Helminthiasis|Nematode Infection|Disease Transmission, Infectious
Interventions: DRUG: albendazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Investigational Drug Study in Adults With Type 2 Diabetes on Basal Insulin (MK-0941-006)
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: MK-0941|DRUG: Placebo|DRUG: LANTUS insulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Safety and Efficacy of Pimavanserin (ACP-103) in Patients With Parkinson's Disease Psychosis
Status: COMPLETED
Conditions: Parkinson's Disease Psychosis
Interventions: DRUG: Pimavanserin tartrate (ACP-103)|DRUG: Pimavanserin tartrate (ACP-103)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Zicronapine in Patients With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Zicronapine|DRUG: Risperidone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility of Mobile-CT-Assisted Bronchoscopy for the Diagnosis of Lung Lesion
Status: ACTIVE_NOT_RECRUITING
Conditions: Lung Neoplasm
Interventions: PROCEDURE: Computed Tomography|OTHER: Electronic Health Record Review|PROCEDURE: Endobronchial Ultrasound Bronchoscopy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Continuous Infusion for Pain Relief
Status: UNKNOWN
Conditions: Regional Anesthesia|Caeserian Section|Local Anesthetic
Interventions: DRUG: control group|DRUG: infiltration group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Brolucizumab vs Aflibercept in Patients With Visual Impairment Due to Diabetic Macular Edema
Status: COMPLETED
Conditions: Diabetic Macular Edema
Interventions: DRUG: Brolucizumab|DRUG: Aflibercept
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Glycaemic Control of Weekly LAPS-Exendin Versus Placebo in Subjects of Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: HM11260C|DRUG: liraglutide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bleomycin, Doxycycline, or Talc in Treating Patients With Malignant Pleural Effusions
Status: COMPLETED
Conditions: Metastatic Cancer
Interventions: BIOLOGICAL: bleomycin sulfate|DRUG: doxycycline|OTHER: talc
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: SUPPORTIVE_CARE
Clinical trial: APP-based Emotion Recognition Training Improve ASD Social Function
Status: RECRUITING
Conditions: Autism Spectrum Disorder High-Functioning
Interventions: BEHAVIORAL: APP-based emotion recognition intervention|BEHAVIORAL: APP-based memory intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Identifying Underserved Individuals inTexas With Hereditary Cancer Risk Using Mobile Mammography Units and Telegenetics.
Status: RECRUITING
Conditions: Ovarian Cancer|Breast Cancer|Colorectal Cancer
Interventions: BEHAVIORAL: Genetic Testing and Counseling|BEHAVIORAL: Screening Form
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Telemonitoring in NIV MND (OptNIVent)
Status: UNKNOWN
Conditions: Motor Neuron Disease, Amyotrophic Lateral Sclerosis
Interventions: OTHER: Telemonitoring via Careportal®
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Immediate vs. On-demand Endoscopic Necrosectomy in Infected Walled-off Pancreatic Necrosis
Status: RECRUITING
Conditions: Pancreatitis, Acute Necrotizing
Interventions: DEVICE: Endoscopic necrosectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RO4929097 After Autologous Stem Cell Transplant in Treating Patients With Multiple Myeloma
Status: WITHDRAWN
Conditions: DS Stage I Plasma Cell Myeloma|DS Stage II Plasma Cell Myeloma|DS Stage III Plasma Cell Myeloma|Refractory Plasma Cell Myeloma
Interventions: PROCEDURE: Autologous Hematopoietic Stem Cell Transplantation|DRUG: Gamma-Secretase Inhibitor RO4929097|PROCEDURE: Hematopoietic Stem Cell Mobilization|PROCEDURE: In Vitro-Treated Peripheral Blood Stem Cell Transplantation|OTHER: Laboratory Biomarker Analysis|DRUG: Melphalan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Docetaxel or Hormone Therapy as Second Line Treatment in Patients With Asymptomatic or Oligosymptomatic Metastatic Castration-resistent Prostate Cancer (mCRPC) Progressing After Abiraterone or Enzalutamide.
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Castration-resistent Prostate Cancer
Interventions: DRUG: Docetaxel|DRUG: Abiraterone Acetate or Enzalutamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pleural Effusion Drainage in Mechanically Ventilated Patients Monitored by EIT
Status: COMPLETED
Conditions: Pleural Effusion|Drainage|Electric Impedance Tomography
Interventions: DEVICE: Electrical Impedance Tomography record
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Chemotherapy, Filgrastim, and Stem Cell Transplantation With Radiation Therapy in Treating Patients With Stage III or Stage IV Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: BIOLOGICAL: filgrastim|DRUG: carboplatin|DRUG: cyclophosphamide|DRUG: ifosfamide|DRUG: thiotepa|PROCEDURE: peripheral blood stem cell transplantation|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Behavior of Biomarkers During Pregnancy and Lactation Through a Biological Multi-paradigm Model: BECOME Study Protocol
Status: COMPLETED
Conditions: Pregnancy|Gestational Diabetes|Hypertension|Obesity
Interventions: OTHER: BEhavior of biomarkers during pregnanCy and lactatiOn
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Extracorporeal Shockwave Therapy Before Postural Correction Exercise in Adults With Forward Head Posture
Status: COMPLETED
Conditions: Neck Pain|Extracorporeal Shock Waves Therapy|Exercise Program
Interventions: DEVICE: Extracorporeal shock waves|BEHAVIORAL: Posture Correction Exercise Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Early Mobilization Following Mini-Open Rotator Cuff Repair
Status: COMPLETED
Conditions: Full Thickness Rotator Cuff Tears
Interventions: PROCEDURE: Sling|PROCEDURE: No sling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: GABA-glutamate Interactions and Psychosis
Status: COMPLETED
Conditions: Cognitive Dysfunction
Interventions: DRUG: iomazenil|DRUG: iomazenil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: NEURODEVELOPMENTAL OUTCOMES OF SINGLETON CONCEIVED FROM FRESH AND FROZEN EMBRYO TRANSFER COMPARED WITH NATURALLY CONCEIVED
Status: UNKNOWN
Conditions: Singeleton Conceived Fresh and Frozen Embryo Transfer (ICSI/IVF), Naturally Conceived
Interventions: OTHER: Assessment by Brazelton neonatal behavior for group A,Band C
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical Study to Investigate the Pharmacokinetic Profiles and Safety of Highdose CKD-385 in Healthy Volunteers(Fasting)
Status: COMPLETED
Conditions: Cardiovascular Diseases
Interventions: DRUG: Reference drug|DRUG: Test drug
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Safety and Effectiveness of Probiotic Supplementation on Bipolar Depression
Status: TERMINATED
Conditions: Bipolar Depression
Interventions: DIETARY_SUPPLEMENT: Bifidobacterium infantis|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The EMPOwER Study Evaluating Multiparameter Gene Testing as a Predictor of Short Term Endocrine Therapy Response in Hormone Receptor Positive Breast Cancers
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: DRUG: Tamoxifen
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Therapeutic Hypothermia After Cardiac Arrest in Non Shockable Rhythm
Status: COMPLETED
Conditions: Cardiac Arrest
Interventions: PROCEDURE: Targeted controlled temperature between 32.5 and 33.5°C|PROCEDURE: Targeted controlled temperature between 36.5 and 37.5°C
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivaelnce Study of Clarithromycin 250 mg/5 mL Powder for Oral Suspension Under Fed Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Clarithromycin 250mg/5mL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Efficacy and Safety Study of OPC-1085EL Ophthalmic Solution in Subjects With Glaucoma or Ocular Hypertension
Status: COMPLETED
Conditions: Glaucoma|Ocular Hypertension
Interventions: DRUG: OPC-1085EL ophthalmic solution|DRUG: Latanoprost ophthalmic solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: HAIC Combined Withzoledronic Acid for the Prevention of Bone Metastases in Advanced HCC
Status: RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: PROCEDURE: HAIC|DRUG: Zoledronic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Exercise on the Symptoms of Premenstrual Syndrome and Dysmenorrhoea and Blood Flow of Genital Tract
Status: COMPLETED
Conditions: Premenstrual Syndrome|Dysmenorrhoea
Interventions: OTHER: Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Biomarkers of Reaction To HIIT Exercise
Status: RECRUITING
Conditions: Stroke|Stroke Rehabilitation|Lower Extremity Weakness, Spastic|Walking, Difficulty
Interventions: OTHER: High Intensity Interval Training (HIIT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Substudy 02D: Safety and Efficacy of Pembrolizumab in Combination With Investigational Agents or Pembrolizumab Alone in Participants With Melanoma Brain Metastasis (MK-3475-02D/KEYMAKER-U02)
Status: ACTIVE_NOT_RECRUITING
Conditions: Melanoma
Interventions: BIOLOGICAL: Pembrolizumab|BIOLOGICAL: Pembrolizumab/Quavonlimab|DRUG: Lenvatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Informing the Relatives of Patients Undergoing Open Heart Surgery
Status: COMPLETED
Conditions: Open Heart Surgery|Life Quality|Caregiver Burden
Interventions: OTHER: informing patients with using a booklet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Toripalimab Plus Actinomycin-D as Fist-Line Treatment for GTN With FIGO Score 5-6
Status: RECRUITING
Conditions: Gestational Trophoblastic Neoplasia
Interventions: DRUG: Toripalimab|DRUG: Actinomycin-D
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intravesical Cabazitaxel, Gemcitabine, and Cisplatin (CGC) in the Treatment Urothelial Carcinoma of the Bladder
Status: ACTIVE_NOT_RECRUITING
Conditions: Urothelial Carcinoma of the Urinary Bladder
Interventions: DRUG: Cabazitaxel|DRUG: Gemcitabine|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of GLP-1 RAs Compared to Basal Insulin Start in Patients Living With Type 2 Diabetes and Chronic Kidney Disease
Status: COMPLETED
Conditions: Type 2 Diabetes|Chronic Kidney Diseases
Interventions: DRUG: GLP-1 receptor agonist|DRUG: basal insulin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Local Anaesthetic Volume on Axillary Brachial Plexus Block Duration
Status: COMPLETED
Conditions: Brachial Plexus Blockade
Interventions: PROCEDURE: Axillary brachial plexus block with 10 mL oof local anaesthetic|PROCEDURE: Axillary brachial plexus block with 30 ml of local anaesthetic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: 3-dimensional Versus 2-dimensional Laparoscopy for Hysterectomy
Status: UNKNOWN
Conditions: Laparoscopy
Interventions: PROCEDURE: 3D laparoscope|PROCEDURE: 2D laparoscope
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Blood Pressure Outcomes With Liraglutide Therapy
Status: COMPLETED
Conditions: Type 2 Diabetes|Systolic Hypertension
Interventions: DRUG: Liraglutide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of Ruxolitinib in Combination With Abemaciclib for the Treatment of Myelofibrosis
Status: RECRUITING
Conditions: Myelofibrosis Due to and Following Polycythemia Vera
Interventions: DRUG: Ruxolitinib|DRUG: Abemaciclib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Comparison of PDT Combination With Ranibizumab vs. Ranibizumab Monotherapy in Persistent PCV With Initial Loading Dose
Status: UNKNOWN
Conditions: Age-related Macular Degeneration
Interventions: PROCEDURE: PDT|DRUG: Ranibizumab|DRUG: ranibizumab PRN
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Early Functional Outcome of Operative Treatment of Displaced Femoral Neck Fractures in Two Kenyan Orthopaedic Centres
Status: COMPLETED
Conditions: Fracture Neck of Femur|Hip Fracture|Femoral Neck Fracture
Interventions: PROCEDURE: Osteosynthesis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Polydeoxyribonucleotide -Placentex Mastelli(Pdrn) for the Treatment of Diabetic Ulcers
Status: COMPLETED
Conditions: Diabetic Ulcer|Foot Ulcer Unhealed
Interventions: DRUG: Polydeoxyribonucleotide|OTHER: 0.9% NaCl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Induction of Ovulation Using Clomiphene Citrate and N-acetyl Cysteine Versus Letrozole
Status: COMPLETED
Conditions: Infertility
Interventions: DRUG: Letrozole|DRUG: Clomiphene Citrate plus N acetyl cystine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intratumor CpG-ODN Injection Boosters Immune Killing Against in Situ Tumor Antigen Release for Advanced Solid Tumors
Status: RECRUITING
Conditions: Lung Cancer|Hepatocellular Carcinoma|Solid Tumor
Interventions: COMBINATION_PRODUCT: CpG-ODN
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intravenous Versus Intra-peritoneal Dexamethasone on the Incidence of Postoperative Nausea and Vomiting
Status: COMPLETED
Conditions: Postoperative Nausea and Vomiting
Interventions: DRUG: Intravenous Dexamethasone|DRUG: Intraperitoneal Dexamesathone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of a Home-Based Rehabilitation on Anthropometric Measures, Sensory-Motor Functions and Independence After Spinal Cord Injury
Status: COMPLETED
Conditions: Spinal Cord Injury at T7-T10 Level|War Injuries Due to Bullets and Fragments|Spinal Cord Injury L1- L5|Spinal Cord Injury No Sensory/Motor in S4-S5
Interventions: OTHER: Home-based Rehabilitation program|DEVICE: Knee-Ankle-Foot-Orthosis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fructose: Substrate, Stimulus, or Both?
Status: RECRUITING
Conditions: Insulin Resistance|Insulin Sensitivity|Pre Diabetes
Interventions: OTHER: High fructose, fructose labeled meal|OTHER: High fructose, pyruvate labeled meal|OTHER: Low fructose, fructose labeled meal|OTHER: Low fructose, pyruvate labeled meal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety and Tolerability Trial of Aripiprazole IM Depot Treatment in Adult Subjects With Schizophrenia Stabilized on Oral Antipsychotics Other Than Aripiprazole
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Aripiprazole IM Depot
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Thrombolysis in Myocardial Ischemia Trial (TIMI III)
Status: COMPLETED
Conditions: Angina Pectoris|Cardiovascular Diseases|Coronary Disease|Heart Diseases|Myocardial Infarction|Myocardial Ischemia
Interventions: DRUG: tissue plasminogen activator|DRUG: heparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Study of Oral Ridaforolimus (AP23573, MK-8669) to Treat Patients With Refractory or Advanced Malignancies (MK-8669-016 AM4)(COMPLETED)
Status: COMPLETED
Conditions: Cancer
Interventions: DRUG: Ridaforolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Video Demonstration and Video Feedback to Reduce Time to Perform Central Vein Cannulation in Junior Residents
Status: UNKNOWN
Conditions: Venous Puncture|Students, Medical|Education, Medical
Interventions: OTHER: VD+VF group|OTHER: VD group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Alisporivir With PEG and RBV in Protease Inhibitor (PI) Treatment Failure Patients With Chronic Hepatitis C
Status: TERMINATED
Conditions: Hepatitis C
Interventions: DRUG: Alisporivir|DRUG: Peginterferon alfa-2a|DRUG: Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MRI in Evaluating the Effect of Efaproxiral on the Brain in Patients With Recurrent or Progressive Glioma Enrolled on Clinical Trial NABTT-9806
Status: WITHDRAWN
Conditions: Brain and Central Nervous System Tumors
Interventions: DEVICE: magnetic resonance imaging (MRI)
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: DIAGNOSTIC
Clinical trial: Standard Surveillance vs. Intensive Surveillance in Early Breast Cancer
Status: RECRUITING
Conditions: Breast Cancer
Interventions: DIAGNOSTIC_TEST: Determination of tumormarkers (CA27.29, CEA, CA125)|DIAGNOSTIC_TEST: Determination of CTC levels|DIAGNOSTIC_TEST: Determination of ctDNA levels|OTHER: Biobanking of blood samples
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy of Aerosal® in the Treatment of Inverse Psoriasis and Sebopsoriasis
Status: WITHDRAWN
Conditions: Inverse Psoriasis|Sebopsoriasis
Interventions: DEVICE: Halotherapy|DEVICE: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase Ib/II Study of LEE011 in Combination With MEK162 in Patients With NRAS Mutant Melanoma
Status: COMPLETED
Conditions: Locally Advanced or Metastatic NRAS Mutant Melanoma
Interventions: DRUG: LEE011|DRUG: MEK162
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Safety of Tofacitinib in Patients With Glucocorticoid Resistant ICIs-related Myocarditis
Status: NOT_YET_RECRUITING
Conditions: Glucocorticoid Resistant ICIs-related Myocarditis
Interventions: DRUG: Tofacitinib 5 MG BID
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ProAgio in Pancreatic Ductal Adenocarcinoma (PDAC)
Status: RECRUITING
Conditions: Pancreatic Ductal Carcinoma
Interventions: DRUG: ProAgio Dose Levels (DL) 1,2,3,4|DRUG: Gemcitabine, nab paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Visceral Pain From the Upper Urinary Tract - a Trial on the Effect of Morphine and Oxycodone in Patients Undergoing PCNL
Status: COMPLETED
Conditions: Kidney Stones
Interventions: DRUG: oxycodone|DRUG: morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transversus Abdominis Plane Block Versus Wound Infiltration for Postcesarean Analgesia
Status: COMPLETED
Conditions: Postcesarean Analgesia
Interventions: PROCEDURE: Spinal anesthesia|DRUG: Intrathecal bupivacaine|DRUG: Intrathecal fentanyl|PROCEDURE: Cesarean delivery|PROCEDURE: Wound infiltration|PROCEDURE: Sham procedure|PROCEDURE: Transversus abdominis plane block|DRUG: Ketorolac|DRUG: Paracetamol|PROCEDURE: Fentanyl patient-controlled analgesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Minimal Residual Disease Assessment in Patients With Colorectal Cancer, the MiRDA-C Study
Status: RECRUITING
Conditions: Colorectal Adenocarcinoma|Stage I Colorectal Cancer AJCC v8|Stage II Colorectal Cancer AJCC v8|Stage IIA Colorectal Cancer AJCC v8|Stage IIB Colorectal Cancer AJCC v8|Stage IIC Colorectal Cancer AJCC v8|Stage III Colorectal Cancer AJCC v8|Stage IIIA Colorectal Cancer AJCC v8|Stage IIIB Colorectal Cancer AJCC v8|Stage IIIC Colorectal Cancer AJCC v8|Stage IV Colorectal Cancer AJCC v6|Stage IVA Colorectal Cancer AJCC v8|Stage IVB Colorectal Cancer AJCC v8|Stage IVC Colorectal Cancer AJCC v8
Interventions: PROCEDURE: Biospecimen Collection|OTHER: Electronic Health Record Review
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The ATtune Knee Outcome Study
Status: RECRUITING
Conditions: Osteoarthritis, Knee|Knee Osteoarthritis|Knee Rheumatism|Rheumatoid Arthritis
Interventions: DEVICE: Total Knee Arthroplasty (uncemented rotating platform ATTUNE)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of T Cells Targeting CD19/BCMA (CART-19/BCMA) for High Risk Multiple Myeloma Followed With Auto-HSCT
Status: UNKNOWN
Conditions: Safety and Efficacy
Interventions: BIOLOGICAL: anti-CD19 and anti-BCMA CAR|DRUG: Immunomodulatory drugs
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of an E-tool Designed to Facilitate Communication Between Allophone Patients and Pediatricians in Emergency Departments.
Status: NOT_YET_RECRUITING
Conditions: Language Barrier
Interventions: OTHER: Use of MARTI application in addition with a classical consultation/support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Trial Investigating the Efficacy and Safety of Insulin Detemir Versus Insulin NPH in Combination With Metformin and Diet/Exercise in Children and Adolescents With Type 2 Diabetes Insufficiently Controlled on Metformin With or Without Other Oral Antidiabetic Drug(s) With or Without Basal Insulin
Status: TERMINATED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: Insulin detemir|DRUG: Insulin NPH|BEHAVIORAL: Diet/exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Workplace Smoking Cessation Program in Hong Kong (Phase VI)
Status: ACTIVE_NOT_RECRUITING
Conditions: Smokers|Workplace|Exercise
Interventions: BEHAVIORAL: mobile phone-based simple physical exercise reminder to help quit smoking|BEHAVIORAL: regular text-based intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Controlled Trial Comparing Transanal Doppler-guided Arterial Ligation With Mucopexy and Stapled Haemorrhoidopexy
Status: COMPLETED
Conditions: Symptomatic Haemorrhoidal Disease Requiring Surgical Management
Interventions: DEVICE: doppler-guided arterial ligation with mucopexy|DEVICE: stapled haemorrhoidopexy according to Longo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I Study of KW-0761 in Relapsed Patients With CCR4-Positive ATL and PTCL
Status: COMPLETED
Conditions: Adult T-Cell Leukemia and Lymphoma (ATL)|Adult Peripheral T-Cell Lymphoma (PTCL)
Interventions: DRUG: KW-0761
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of SON-1010 (IL12-FHAB) in Healthy Adults
Status: COMPLETED
Conditions: Healthy Adult
Interventions: BIOLOGICAL: SON-1010 (IL12-FHAB)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: NovoTTF-100A Therapy for Refractory CNS Involved Small Cell Lung Cancer
Status: WITHDRAWN
Conditions: Small Cell Lung Cancer|Brain Metastasis
Interventions: DEVICE: NovoTTF-100A plus chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Laser Therapy in the Management of Adhesive Capsulitis: a Randomized Clinical Trial
Status: UNKNOWN
Conditions: Pain Disorder|Low Level Laser Therapy
Interventions: OTHER: Low-level laser therapy|OTHER: High-intensity laser therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Compare Continuing Lamivudine Plus Adefovir or Adefovir Versus Switching to Entecavir Plus Adefovir in Patients With LAM-resistant Chronic Hepatitis B
Status: UNKNOWN
Conditions: Hepatitis B, Chronic
Interventions: DRUG: Lamivudine|DRUG: Adefovir|DRUG: Entecavir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT