pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Prospective, Assessment of Vitamin D and Calcium Supplementation, Improvement of Nutritional Status and Preoperative Rehabilitation in Patients Before Knee Arthroplasty.
Status: COMPLETED
Conditions: Knee Osteoarthritis|Vitamin D Deficiency|Pain, Postoperative|Arthropathy of Knee
Interventions: BEHAVIORAL: Intervention group 1|BEHAVIORAL: Intervention group 2|BEHAVIORAL: Control group 0
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Feasibility Study Over the NAVA Mode in Noninvasive Ventilation After Cardiac Surgery in Infants.
Status: COMPLETED
Conditions: Heart Defects, Congenital|Surgery
Interventions: DEVICE: NivNava|DEVICE: Cpap
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Implementation of the Hemispheric Dominance During Development
Status: ACTIVE_NOT_RECRUITING
Conditions: Neuroimaging
Interventions: DEVICE: Electroencephalogram (EEG)|DEVICE: Near Infra Red Spectroscopy (NIRS)|DEVICE: magnetic resonance imaging (MRI)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Intracorporeal Versus Extracorporeal Anastomotic After Laparoscopic Right Colectomy
Status: NOT_YET_RECRUITING
Conditions: Colon Cancer
Interventions: PROCEDURE: Intracorporeal anastomotic after LRC|PROCEDURE: Extracorporeal anastomotic after LRC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Abdominal Drains on the ERAS Pathway in Peptic Perforation
Status: RECRUITING
Conditions: Perforated Peptic Ulcer|Fast Track Surgery|Perforated Bowel|Post-Op Complication|Emergencies
Interventions: OTHER: ERAS protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Patient Centered Algorithms to Optimize the Inpatient Experience and Treatment of Ulcerative Colitis
Status: COMPLETED
Conditions: Colitis, Ulcerative|Inflammatory Bowel Diseases|Colitis|Intestinal Disease
Interventions: OTHER: Educational video
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: 8% Sulphur-Aloe Vera Soap as an Adjuvant Treatment for Pityriasis Versicolor
Status: COMPLETED
Conditions: Pityriasis Versicolor
Interventions: DRUG: 8% sulphur and A. vera soap
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Typhoid Conjugate Vaccine Trial Among Children Younger Than 2 Years in Ouagadougou, Burkina Faso
Status: COMPLETED
Conditions: Typhoid
Interventions: BIOLOGICAL: Vi-Typhoid Conjugate Vaccine (Vi-TCV)|BIOLOGICAL: Inactivated Poliovirus Vaccine (IPV)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Multi-antigen CMV-MVA Triplex Vaccine in Reducing CMV Complications in Patients Previously Infected With CMV and Undergoing Donor Hematopoietic Cell Transplant
Status: ACTIVE_NOT_RECRUITING
Conditions: Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive|Acute Lymphoblastic Leukemia in Remission|Acute Myeloid Leukemia in Remission|Chronic Lymphocytic Leukemia|Chronic Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive|Cytomegaloviral Infection|Hodgkin Lymphoma|Lymphadenopathy|Lymphoblastic Lymphoma|Myelodysplastic Syndrome|Myelofibrosis|Myeloproliferative Neoplasm|Non-Hodgkin Lymphoma
Interventions: OTHER: Laboratory Biomarker Analysis|BIOLOGICAL: Multi-peptide CMV-Modified Vaccinia Ankara Vaccine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: E-CEL UVEC Cells as an Adjunct Cell Therapy for the Arthroscopic Rotator Cuff Repair in Adults
Status: ACTIVE_NOT_RECRUITING
Conditions: Rotator Cuff Tears|Muscle Atrophy or Weakness|Tendon Rupture - Shoulder|Safety Issues
Interventions: DRUG: E-CEL UVEC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Safety and Efficacy of KTE-C19 in Combination With Atezolizumab in Adults With Refractory Diffuse Large B-Cell Lymphoma (DLBCL)
Status: COMPLETED
Conditions: Refractory Diffuse Large B Cell Lymphoma
Interventions: BIOLOGICAL: KTE-C19|BIOLOGICAL: Atezolizumab|DRUG: Cyclophosphamide|DRUG: Fludarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Occurrence of Single Nucleotide Polymorphism Among Women Who Experienced Obstetric Anal Sphincter Injury
Status: COMPLETED
Conditions: Delivery, Obstetric
Interventions: GENETIC: screening for single nucleotide polymorphism|GENETIC: whole exome sequencing
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Calcitriol, Physical Activity, and Bone Health in Cancer Survivors
Status: COMPLETED
Conditions: Breast Neoplasms|Bone and Bones
Interventions: DRUG: Calcitriol|BEHAVIORAL: Exercise|DIETARY_SUPPLEMENT: Multivitamin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Response Rate and Side Effects of Preoperative Chemotherapy (TOX Regimen) in Patients With Locally Advanced Operable Gastric Adenocarcinoma
Status: COMPLETED
Conditions: Gastric Cancer
Interventions: DRUG: TOX
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Postnatal Enalapril to Improve Cardiovascular fUnction Following Preterm Pre-eclampsia
Status: COMPLETED
Conditions: Cardiovascular Diseases|Pre-Eclampsia Onset Less Than 37 Weeks (Diagnosis)
Interventions: DRUG: Enalapril Maleate|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II Study of Thalidomide, Clarithromycin, Lenalidomide, and Dexamethasone for Newly Diagnosed Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: thalomid|DRUG: lenalidomide|DRUG: clarithromycin|DRUG: dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety and Efficacy Study of Daikenchuto (TU-100) to Treat Crohn's Disease
Status: TERMINATED
Conditions: Crohn's Disease
Interventions: DRUG: TU-100|DRUG: Matching Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Nusinersen Among Participants With Spinal Muscular Atrophy Who Received Onasemnogene Abeparvovec
Status: ACTIVE_NOT_RECRUITING
Conditions: Muscular Atrophy, Spinal
Interventions: DRUG: Nusinersen
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hypofractionated Radiotherapy With Carboplatin and Paclitaxel in Non-Small Cell Lung Cancer
Status: WITHDRAWN
Conditions: Non Small Cell Lung Cancer
Interventions: RADIATION: 2.5 Gy/fraction|DRUG: Carboplatin|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Increased Risk of SARS-CoronaVirus-2 (SARS-CoV-2) Infection Associated With Endoscopy (DECORE Study)
Status: COMPLETED
Conditions: SARS-CoV 2|COVID
Interventions: BEHAVIORAL: Telephonic medical visit|PROCEDURE: Gastrointestinal endoscopy|PROCEDURE: Abdominal ultrasound
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Computer-aided Detection During Screening Colonoscopy (Experts)
Status: UNKNOWN
Conditions: Colorectal Neoplasms|Colon Polyp|Colon Adenoma
Interventions: DIAGNOSTIC_TEST: Standard high-definition colonoscopy|DIAGNOSTIC_TEST: Colonoscopy with real-time AI assisted automated polyp detection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Pharmacokinetic Study of Fentanyl 400 µg Sublingual Spray, Actiq® 400 µg Transmucosally, and Fentanyl Citrate Injection 100 µg Intravenously (iv)
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Fentanyl 400 µg sublingual spray|DRUG: Actiq® 400 µg transmucosally|DRUG: Fentanyl citrate injection 100 µg intravenously|DRUG: Naltrexone 50 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Two Pharmacological Protocols for Pre-emptive Analgesia in Impacted Third Molar Surgery
Status: COMPLETED
Conditions: Pain|Edema|Trismus
Interventions: DRUG: Dexamethasone|DRUG: Diclofenac Sodium associated with Codeine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Wearing-Off Period of Pharmacological Dilation and Anisocoria
Status: COMPLETED
Conditions: Anisocoria
Interventions: DRUG: Tropicamide|DRUG: 1% Pilocarpine|DRUG: Proparacaine Hydrochloride|DEVICE: Tono pen AVIA|DEVICE: VG4 Gonio|DEVICE: Reichert phoropter
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Retinal Displacement After Pneumatic Versus Vitrectomy for Retinal Detachment (ALIGN)
Status: COMPLETED
Conditions: Retinal Detachment|Metamorphopsia|Aniseikonia
Interventions: PROCEDURE: Pneumatic Retinopexy|PROCEDURE: Pars Plana Vitrectomy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Comparison Study of Prototype Continuous Glucose Sensors in the Intradermal and Subcutaneous Spaces
Status: COMPLETED
Conditions: Diabetes
Interventions: DEVICE: BD Continuous glucose monitor (BD CGM)|DEVICE: YSI Glucose Analyzer|DEVICE: Medtronic Guardian CGM
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Web-based Mind-body Program for Comorbid Nontraumatic Upper-extremity Condition and Risky Substance Use
Status: NOT_YET_RECRUITING
Conditions: Orthopedic Disorder|Nontraumatic Injury|Substance Use|Upper Extremity Problem
Interventions: BEHAVIORAL: Web-TIRELESS
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Promoting Recovery Outcomes Through Precise Early Locomotor Interventions in Persons With Spinal Cord Injury
Status: RECRUITING
Conditions: Spinal Cord Injuries
Interventions: PROCEDURE: Body Weight Supported Treadmill Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: α-lipoic Acid (ALA), Magnesium, Vitamin B6 and Vitamin D and Risk Factor for Pre-term Birth
Status: COMPLETED
Conditions: Cervical Shortening|Preterm Birth
Interventions: DIETARY_SUPPLEMENT: Dav
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety and Effectiveness of Buprenorphine Transdermal System in Elderly Subjects With Chronic Pain: Pilot Study.
Status: COMPLETED
Conditions: Chronic Pain
Interventions: DRUG: Buprenorphine transdermal delivery system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of C-Mill Treadmill Training Versus Conventional Treadmill on Balance and Psychological Status in Elderly
Status: NOT_YET_RECRUITING
Conditions: Elderly|Geriatric
Interventions: DEVICE: C mell treadmill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Asciminib Treatment Optimization in ≥ 3rd Line CML-CP.
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Myelogenous Leukemia
Interventions: DRUG: ABL001 40mg BID|DRUG: ABL001 80mg QD|DRUG: ABL001 200mg QD
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Quality of Life After Esophagectomy for Cancer - Step 2
Status: TERMINATED
Conditions: Esophageal Cancer|Quality of Life
Interventions: BEHAVIORAL: nutritional counseling|BEHAVIORAL: respirology counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PROphylaxis for paTiEnts at Risk of COVID-19 infecTion -V
Status: RECRUITING
Conditions: Covid19
Interventions: DRUG: Niclosamide|DRUG: Placebo|DRUG: Ciclesonide|DRUG: Placebo|DRUG: Sotrovimab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Early Psychological Intervention After Rape
Status: RECRUITING
Conditions: Post Traumatic Stress Disorder|Rape Sexual Assault|Sexual Dysfunctions, Psychological|Pelvic Floor Myalgia|Pelvic Pain Syndrome|Depression, Anxiety|Sleep Disturbance|Activity, Motor|Cortisol Deficiency
Interventions: BEHAVIORAL: Modified prolonged exposure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Intravenous Infusions of Ferumoxytol Compared to Oral Ferrous Sulfate for the Treatment of Anemia in Pregnancy
Status: COMPLETED
Conditions: Iron Deficiency Anemia of Pregnancy
Interventions: DIETARY_SUPPLEMENT: Ferrous sulfate 325mg|DRUG: Ferumoxytol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness and Safety of Yisaipu Combined With Tripterygium Wilfordii for Active RA
Status: COMPLETED
Conditions: Arthritis, Rheumatoid
Interventions: DRUG: Tripterygium Wilfordii|DRUG: Methotrexate|DRUG: Yisaipu
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of FMT for the Decolonization of MDROs in the Intestinal Tract
Status: RECRUITING
Conditions: Carbapenem-Resistant Enterobacteriaceae|Vancomycin (Glycopeptide) Resistant Enterococcus (VRE)
Interventions: PROCEDURE: fecal microbiota transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Performance of Bulk Fill Composite With Activa Bioactive Liner
Status: COMPLETED
Conditions: Clinical Study of Activa Bioactive Restorative|Dental Caries
Interventions: OTHER: Activa Bioactive
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Wireless TENS for Peripheral Edema (Lower Limb Swelling)
Status: ACTIVE_NOT_RECRUITING
Conditions: Peripheral Edema
Interventions: DEVICE: Transcutaneous Electrical Nerve Stimulation (TENS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Endodontic Postoperative Pain Using Different Irrigation Systems
Status: RECRUITING
Conditions: Postoperative Pain|Irreversible Pulpitis
Interventions: PROCEDURE: endodontic needle (EN)|PROCEDURE: Endodontic activation (EA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Pentoxifylline Versus Pioglitazone In Non-Alcoholic Steatohepatiti (NASH)
Status: UNKNOWN
Conditions: Metabolic Parameters and Liver Histology
Interventions: DRUG: Pioglitazone|DRUG: Pioglitazone|DRUG: Pentoxifylline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of a Live Herpes Zoster Vaccine and a Recombinant Vaccine in 50-59 and 70-85 Year Olds
Status: COMPLETED
Conditions: Shingles|Herpes Zoster
Interventions: BIOLOGICAL: Zostavax|BIOLOGICAL: HZ/su vaccine|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Single Ascending Dose Study With 5-MeO-DMT in Healthy Subjects
Status: COMPLETED
Conditions: Pharmacokinetics in Healthy Adults
Interventions: DRUG: 5-MeO-DMT|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Single Arm Study Evaluating the Efficacy and Safety of Pralatrexate in Subjects With Relapsed or Refractory PTCL
Status: COMPLETED
Conditions: Refractory Peripheral T-Cell Lymphoma|Relapsed T-Cell Lymphoma
Interventions: DRUG: pralatrexate|DIETARY_SUPPLEMENT: Vitamin B12 and folic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of GFH009 in Combination With Zanubrutinib in Subjects With Relapsed or Refractory DLBCL
Status: RECRUITING
Conditions: Large B-cell Lymphoma
Interventions: DRUG: GFH009|DRUG: Zanubrutinib|DRUG: GFH009|DRUG: Zanubrutinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: iSGLT2 Inhibitor and a iDPP -4 Inhibitor in Treatment of Type 2 Diabetes Mellitus in Patients Treated With Metformin (TRIAD)
Status: NOT_YET_RECRUITING
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: N0892|DRUG: Januvia® + Glifage XR® + Placebo|DRUG: Forxiga® + Glifage XR® + Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Masitinib in Combination With Gemcitabine for Treatment of Patients With Advanced/Metastatic Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DRUG: Masitinib|DRUG: Placebo|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Adjuvant Versus Neo-adjuvant Radiotherapy in Patients With Resectable Soft Tissue Sarcoma in Extremities : Wound Complications
Status: ACTIVE_NOT_RECRUITING
Conditions: Resectable Soft Tissue Sarcoma|Extremities|Radiotherapy Wound Complications
Interventions: PROCEDURE: surgical resection with safety margin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Accelerated Repetitive Transcranial Magnetic Stimulation on Patients With Post-stroke Depression
Status: COMPLETED
Conditions: Post-stroke Depression
Interventions: DEVICE: The Magstim Rapid2 Plus Magnetic Stimulator (Magstim, Whitland, Dyfed, UK)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Omega -3 Supplements on the Serum Levels of ACE/ACE2 Ratio as a Potential Key in Cardiovascular Disease and COVID-19; A Randomized Clinical Trial in the Covid-19 Uninfected Jordanian People
Status: COMPLETED
Conditions: Cardiovascular Risk Factor|Covid19
Interventions: DIETARY_SUPPLEMENT: 300 mg of omega3-FA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Impact of Pegfilgrastim on Trastuzumab Anti-tumor Effect and ADCC in Operable HER2+ Breast Cancer Breast Cancer
Status: RECRUITING
Conditions: HER2-positive Breast Cancer|Operable Breast Cancer
Interventions: DRUG: Trastuzumab + Paclitaxel|DRUG: Pegfilgrastim
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility of Obtaining Pulse Oximetry Readings From the Oropharynx
Status: ENROLLING_BY_INVITATION
Conditions: Surgery|Arterial Catheterization, Peripheral
Interventions: DEVICE: Pulse oximetry
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Sensitivity of Multiparametric MRI in Differentiation Between Muscle Invasive and Non-muscle Invasive Urinary Bladder Cancer
Status: COMPLETED
Conditions: Cancer, Bladder
Interventions: RADIATION: multiparametric MRI on the bladder|PROCEDURE: diagnostic cystoscopy +/- TURBT
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Personal Protective Equipment for the Prevention of SARS-Cov-2 During Neonatal Resuscitation
Status: COMPLETED
Conditions: Neonates Needing Resuscitation at Birth
Interventions: PROCEDURE: Neonatal resuscitation with PPE for the prevention of SARS-Cov-2 infection|PROCEDURE: Neonatal resuscitation without PPE for the prevention of SARS-Cov-2 infection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Peripheral Chemoreflex/Arterial Baroreflex Interaction in Patients With Electrical Carotid Sinus Stimulation
Status: COMPLETED
Conditions: Hypertension, Resistant to Conventional Therapy
Interventions: OTHER: Hypoxia without dopamine|OTHER: Hypoxia with dopamine|OTHER: Hyperoxia without dopamine|OTHER: Hyperoxia with dopamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Relative Bioavailability Study of Metformin HCL Tablets, 1000 mg Under Fasting Conditions
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: Metformin HCL Tablets, 1000 mg Sandoz|DRUG: Glucophage 1000 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Omitting Clinical Target Volume of Unresectable Stage III Non-small-cell Lung Cancer.
Status: COMPLETED
Conditions: Stage III Non-small-cell Lung Cancer
Interventions: RADIATION: The enrollment was randomly (1:1) assigned into the study group with CTV-omitted IMRT under PET-CT guidance and the control group with CTV-delineated IMRT using a random number table.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Video-assisted Mobilisation Training on Mobility, Anxiety and Pain After Coronary Artery Bypass Surgery
Status: COMPLETED
Conditions: Anxiety|Postoperative Pain
Interventions: OTHER: video assisted mobilization training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effectiveness of a Barbershop-Based Program to Improve High Blood Pressure Control and Awareness in Black Men
Status: COMPLETED
Conditions: Hypertension
Interventions: BEHAVIORAL: Baseline BP Screening|OTHER: Intensive 10-week Blood Pressure Screening
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Anemia Studies in Chronic Kidney Disease (CKD): Erythropoiesis Via a Novel Prolyl Hydroxylase Inhibitor (PHI) Daprodustat-Three-times Weekly Dosing in Dialysis (ASCEND-TD)
Status: COMPLETED
Conditions: Anaemia
Interventions: DRUG: Daprodustat tablets|DRUG: Matching placebo tablets|DRUG: Epoetin alfa vials|DRUG: Saline vials or bags
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: HIIT vs MICT During Pregnancy and Health and Birth Outcomes in Mothers and Children
Status: RECRUITING
Conditions: Pregnancy|Postpartum|Childbirth|Health Status|Physical Fitness|Noncommunicable Diseases|Metabolism|Diabetes Mellitus, Gestational|Pregnancy Induced Hypertension|Body Composition|Back Pain|Pain Threshold|Biomechanics|Pelvic Floor Disorders|Urinary Incontinence|Cognitive Function|Depression|Anxiety
Interventions: BEHAVIORAL: High intensity interval training program for pregnant women|BEHAVIORAL: Moderate intensity continuous training program for pregnant women|BEHAVIORAL: Standard obstetric care with extended education on healthy lifestyle|BEHAVIORAL: High intensity interval training program for nonpregnant women|BEHAVIORAL: Moderate intensity continuous training program for nonpregnant women|BEHAVIORAL: Standard health care with extended education on healthy lifestyle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluate Onset of Effect in Patients With Chronic Obstructive Pulmonary Disease (COPD) Treated With Formoterol Turbuhaler®
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Formoterol|DRUG: Salmeterol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pair Antiplatelet THerapy in Ischemic Stroke With Intracranial Artery Stenosis
Status: NOT_YET_RECRUITING
Conditions: Ischemic Stroke|Intracranial Arteriosclerosis|Secondary Prevention|Antiplatelet Drug
Interventions: DRUG: clopidogrel for 90 days combined with aspirin for 90 days|DRUG: clopidogrel for 30 days combined with aspirin for 90 days
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Arsenic Trioxide and Imatinib Mesylate in Treating Patients With Accelerated Phase or Blastic Phase Chronic Myelogenous Leukemia or Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia
Status: COMPLETED
Conditions: Leukemia
Interventions: DRUG: arsenic trioxide|DRUG: imatinib mesylate
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Switch From Adefovir to Tenofovir in Chronic Hepatitis B for Suboptimal Response to Adefovir-based Combination Therapy
Status: UNKNOWN
Conditions: Chronic Hepatitis B
Interventions: DRUG: Switching from adefovir (10mg/day) to tenofovir (300mg/day)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics and Bioequivalence of Doxylamine + Pyridoxine, Film-coated, Enteric-soluble Tablets, and Diclectin, Delayed Release Tablets, in Healthy Volunteers
Status: COMPLETED
Conditions: Pregnancy Related|Nausea
Interventions: DRUG: Doxylamine + Pyridoxine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Iodine Status in Swedish Lactating Women - Effect of Iodine Supplementation in the Thyroid Function of Mother and Infant
Status: TERMINATED
Conditions: Thyroid Gland; Node|Lactation
Interventions: DIETARY_SUPPLEMENT: iodine|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Chronic Graft-versus-Host Disease Treatment (BMT CTN 0801)
Status: COMPLETED
Conditions: Chronic GVHD
Interventions: DRUG: Sirolimus + calcineurin inhibitor + prednisone|DRUG: Sirolimus + prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Study of CIM331 for Atopic Dermatitis Patients
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: nemolizumab (CIM331)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Benefits of Intracytoplasmic Morphologically Selected Sperm Injection (IMSI) in Couples With Unexplained Infertility
Status: WITHDRAWN
Conditions: Pregnancy
Interventions: OTHER: ICSI|OTHER: IMSI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Low Dose Liraglutide and Metformin vs. High Dose Liraglutide Alone in Treatment of Obesity
Status: COMPLETED
Conditions: Polycystic Ovary Syndrome|Obesity
Interventions: DRUG: liraglutide|DRUG: metformin and liraglutide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gamma tACS in Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer Disease
Interventions: DEVICE: Gamma tACS (40 Hz) over the superior parietal cortex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Romidepsin and Abraxane in Treating Patients With Metastatic Inflammatory Breast Cancer
Status: TERMINATED
Conditions: HER2-negative Breast Cancer|Inflammatory Breast Cancer|Male Breast Cancer|Recurrent Breast Cancer|Stage IV Breast Cancer
Interventions: DRUG: Romidepsin|DRUG: Abraxane
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Liothyronine on Energy Expenditure and Cardiovascular Function
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Liothyronine|DRUG: Levothyroxine|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Evaluation of [18F] FEPPA and PET Imaging as a Marker of Inflammation in Subjects With Neurological Conditions
Status: COMPLETED
Conditions: Alzheimer Disease|Parkinson Disease|Multiple Sclerosis
Interventions: DRUG: [18F]-FEPPA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Clinical Evaluation of the XIENCE PRIME Small Vessel Everolimus Eluting Coronary Stent System in Japanese Population
Status: COMPLETED
Conditions: Vascular Disease|Myocardial Ischemia|Coronary Artery Stenosis|Coronary Disease|Coronary Artery Disease|Coronary Restenosis
Interventions: DEVICE: XIENCE PRIME SV EECSS
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Light Therapy Plus Exercise to Improve Motor, Non-Motor Symptoms and QoL in Parkinson's Disease
Status: RECRUITING
Conditions: Parkinson's|Disease
Interventions: DEVICE: Infrared laser photobiomodulation device|DEVICE: Infrared & Red LED photobiomodulation device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Altering The Transition From Acute to Chronic Pain (ATTAC-Pain)
Status: COMPLETED
Conditions: Musculoskeletal Pain
Interventions: DRUG: Duloxetine 30 milligrams (MG)|DRUG: Duloxetine 60 milligrams (MG)|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Socioeconomic Determinants of the Chemical Exposome and Its Genotoxic Effects in Children
Status: RECRUITING
Conditions: Healthy Volunteer Children
Interventions: OTHER: Hair cut|OTHER: Socio-economic questionnaires
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: First-line Replacement Maintenance of Envafolimab in Advanced NSCLC
Status: NOT_YET_RECRUITING
Conditions: Non-Small-Cell Lung
Interventions: DRUG: Envafolimab;Pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Trial of TD 6424 (Telavancin) Versus Standard Therapy for Complicated Gram Positive Skin and Skin Structure Infections (Gram Positive cSSSI)
Status: COMPLETED
Conditions: Infections, Gram-Positive Bacterial|Abscess|Burns|Cellulitis|Ulcer|Wound Infections
Interventions: DRUG: Telavancin|DRUG: Vancomycin or antistaphylococcal penicillin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dismantling the U.S. Social Norm of the "Kids' Food" Archetype (REACH Project)
Status: RECRUITING
Conditions: Food Selection|Environmental Exposure
Interventions: BEHAVIORAL: Conventional Ultra-processed Food Nutrition Education|BEHAVIORAL: Arts-based Ultra-processed Food Nutrition Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Dry Needling and High Intensity Laser Therapy in Treatment of Myofascial Pain Syndrome
Status: COMPLETED
Conditions: Myofascial Pain Syndrome
Interventions: OTHER: dry needle|DEVICE: high intensity laser therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Mesenchymal Stem Cells Enhanced With PRP Versus PRP In OA Knee
Status: UNKNOWN
Conditions: Osteoarthritis, Knee
Interventions: BIOLOGICAL: Mesenchymal stem cell suspension|BIOLOGICAL: PRP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Three Variants of Canaloplasty With Phacoemulsification to Treat Glaucoma and Cataract
Status: UNKNOWN
Conditions: Primary Open Angle Glaucoma, Cataract
Interventions: PROCEDURE: canaloplasty and phacoemulsification
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1/2, Study of YL-15293 in Subjects With Advanced Solid Tumors With a KRAS G12C Mutation
Status: UNKNOWN
Conditions: Advanced Solid Tumor
Interventions: DRUG: YL-15293
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Circulating Human Papilloma Virus (HPV) DNA for the Screening and Surveillance of Gynecologic Cancers
Status: RECRUITING
Conditions: Cervical Dysplasia|Cervical Cancer
Interventions: DIAGNOSTIC_TEST: NavDx(R)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of Gemcitabine, Cisplatin, AB680 and AB122 During First Line Treatment of Advanced Biliary Tract Cancers (QUIC)
Status: RECRUITING
Conditions: Biliary Tract Carcinoma|Cholangiocarcinoma|Bile Duct Cancer
Interventions: DRUG: Gemcitabine|DRUG: Cisplatin|DRUG: Zimberelimab|DRUG: Quemliclustat
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Parental Notions and Clinical Experiences About Child's Gut Comfort, Overall Satisfaction and Sense of Well-being When Consuming a New Toddler Milk
Status: COMPLETED
Conditions: Digestion|Happiness|Temperament
Interventions: DIETARY_SUPPLEMENT: Toddler Milk
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Phase 2B Upper Extremity Nerve Block Study
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: HTX-011|DRUG: Bupivacaine HCl without epinephrine|DRUG: Saline Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Scalp Nerve Blocks on Systemic Inflammation
Status: UNKNOWN
Conditions: Meningiomas
Interventions: PROCEDURE: Scalp Nerve Blocks With Ropivacaine|PROCEDURE: Scalp Nerve Blocks With Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacies of Different Managements in Patients With Overactive Bladder With Stroke
Status: ACTIVE_NOT_RECRUITING
Conditions: Incontinence, Urge|Stroke|Neurogenic Bladder
Interventions: DEVICE: Tibial Nerve Stimulation with TENS device|BEHAVIORAL: Pelvic muscle training exercise with bladder training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mono-menotropins Versus rFSH Protocol on Embryo Quality
Status: COMPLETED
Conditions: Infertility|Fertility
Interventions: DRUG: menotropin|DRUG: Recominant Follicle Stimulating Hormone (rFSH)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of Probiotics on Clinical Parameters, the Oral Microbiome and the Immune System During an Orthodontic Treatment
Status: UNKNOWN
Conditions: Gingivitis|Orthodontic Appliance Complication
Interventions: DIETARY_SUPPLEMENT: Lactobacillus reuteri Prodentis®-lozenges (DSM 17938, ATCC PTA 5289)|DIETARY_SUPPLEMENT: Placebo-lozenges (BioGaia)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Safety and Tolerability Study of Clofarabine, Etoposide, Cyclophosphamide, PEG-asparaginase, and Vincristine in Pediatric Acute Lymphoblastic Leukemia (ALL)
Status: COMPLETED
Conditions: Lymphoblastic Leukemia, Acute, Childhood
Interventions: DRUG: Clofarabine incorporated into a 5-drug regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Apixaban Drug Utilization Study In Stroke Prevention In Atrial Fibrillation (Spaf)
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DRUG: apixaban|DRUG: dabigatran|DRUG: VKA|DRUG: rivaroxaban
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Medication Adherence Between Once and Twice Daily Tacrolimus in Stable Renal Transplant Recipients
Status: COMPLETED
Conditions: Renal Disease|Renal Transplant
Interventions: DRUG: Tacrolimus - Prograf® twice daily formulation|DRUG: Tacrolimus - Advagraf® once daily formulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Bioequivalence of Oral Formulations of Anastrozole in Healthy Chinese Volunteers Under Fasted Condition
Status: UNKNOWN
Conditions: Healthy Volunteers
Interventions: DRUG: test-anastrozole tablet (Salutas Pharma GmbH)|DRUG: reference-anastrozole tablet (Arimidex)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Extension Protocol for Patients Who Previously Completed the TMS Pilot Study
Status: TERMINATED
Conditions: Schizophrenia and Related Disorders
Interventions: DEVICE: Repetitive Transcranial Magnetic Stimulation (rTMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tow Techniques of Adductor Canal Block for Analgesia After Total Knee Replacement
Status: COMPLETED
Conditions: Total Knee Arthroplasty|Analgesia|Nerve Block
Interventions: PROCEDURE: ultrasound-guided short-axis placement of catheter at the entrance of the adductor canal|PROCEDURE: ultrasound-guided long-axis placement of catheter at the middle of the adductor canal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Tislelizumab Combined With Mitoxantrone Hydrochloride Liposome in Extranodal Natural Killer/T Cell Lymphoma
Status: RECRUITING
Conditions: Extranodal Natural Killer T Cell Lymphoma
Interventions: DRUG: Tislelizumab combined with Liposomal mitoxantrone hydrochloride|DRUG: Maintenance of tislelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Resistance Training With and Without Plyometric Exercises on Athletes With Chronic Ankle Instability.
Status: RECRUITING
Conditions: Chronic Ankle Instability
Interventions: OTHER: Resistance Exercises with Plyometric exercises|OTHER: Resistance Exercises without Plyometric exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: National Clinical-biological Prospective Cohort of Incident Cases of Aggressive Fibromatosis (ALTITUDES)
Status: ACTIVE_NOT_RECRUITING
Conditions: Aggressive Fibromatosis
Interventions: PROCEDURE: biopsy|OTHER: biobank constitution|PROCEDURE: Coloscopy|PROCEDURE: Blood sampling (facultative)|OTHER: Pain evaluation|PROCEDURE: Tumor biobank realization
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Sensory Integration Versus Fine Motor Intervention in Children With Autism
Status: COMPLETED
Conditions: Autism Spectrum Disorder
Interventions: OTHER: fine motor skills|OTHER: sensory integration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Atomoxetine in Children With ADHD to Assess Symptomatic and Functional Outcomes
Status: COMPLETED
Conditions: Attention-Deficit/Hyperactivity Disorder
Interventions: DRUG: Atomoxetine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Repeated Transcranial Magnetic Stimulation in the Elderly With Cognitive Impairment
Status: RECRUITING
Conditions: Dementia|Cognitive Impairment, Mild
Interventions: DEVICE: High-frequency repetitive transcranial magnetic stimulation (40Hz)|DEVICE: Moderately high-frequency repetitive transcranial magnetic stimulation (10Hz)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Telerehabilitation, Core Stability Exercises and Hereditary Ataxia (TRCore-ataxia)
Status: ACTIVE_NOT_RECRUITING
Conditions: Hereditary Ataxia|Spinocerebellar Degenerations|Cerebellar Ataxia
Interventions: OTHER: Therapeutic core stability exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of LEO 39652 Cream in Adults With Mild to Moderate Atopic Dermatitis (AD)
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: LEO 39652 cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Clinical Trial of MARI
Status: NOT_YET_RECRUITING
Conditions: Posttraumatic Stress Disorder|Anger
Interventions: BEHAVIORAL: Mobile Anger Reduction Intervention (MARI)|BEHAVIORAL: Health Education Condition (HED)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: HBsAg Decline After Pegylated-interferon-α in e Antigen Positive Chronic Hepatitis B With Nucleoside Maintenance
Status: UNKNOWN
Conditions: Chronic Hepatitis B
Interventions: DRUG: PEG-interferon-Alfa-2A|DRUG: Nucleosides
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Coolant Spray on Traumatic Rib Pain of Geriatric Patients
Status: COMPLETED
Conditions: Thorax; Fracture|Pain; Thorax, Thoracic, Spine, With Radicular and Visceral Pain
Interventions: DRUG: Coolant spray (Cryos ®Spray, Phyto Performance, Italy)|DRUG: Saline solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Ledipasvir/Sofosbuvir Fixed-Dose Combination for 12 Weeks in Participants With Chronic Genotype 2 HCV Infection
Status: COMPLETED
Conditions: Hepatitis C Virus Infection
Interventions: DRUG: LDV/SOF|DRUG: SOF|DRUG: RBV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Apnea-Hypopnea Index in Patients With or Without Preventive Oxygen Therapy After Bariatric Surgery
Status: RECRUITING
Conditions: Obstructive Sleep Apnea|Obesity|Bariatric Surgery Candidate
Interventions: OTHER: No preventive oxygen therapy (2L)|OTHER: Preventive oxygen therapy (2L) standard care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Study of BMS-754807 and Herceptin® in Patients With Advanced or Metastatic Her-2-positive Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: BMS-754807|DRUG: trastuzumab (Herceptin®)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT