pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Phase 1/Phase 2 Study of Polyvalent Pneumococcal Conjugate Vaccine (V116) in Adults (V116-001)
Status: COMPLETED
Conditions: Pneumonia, Pneumococcal
Interventions: BIOLOGICAL: V116|BIOLOGICAL: Pneumovax™23
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Prophylactic Antibiotics for Prevention of Wound Complications Following Vulvectomy
Status: COMPLETED
Conditions: Wound Infection
Interventions: DRUG: Cefazolin PostOperatively|DRUG: Cefazolin Preoperatively
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Does Sildenafil Improve Endothelial Dysfunction in Rheumatoid Arthritis?
Status: TERMINATED
Conditions: Arthritis, Rheumatoid|Atherosclerosis
Interventions: DRUG: Sildenafil|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Hämeenlinna Metabolic Syndrome Research Program: Effects of Rapeseed Oil on Serum Lipids and Platelet Function
Status: COMPLETED
Conditions: Metabolic Syndrome
Interventions: DIETARY_SUPPLEMENT: Cold-pressed turnip rapeseed oil (CTPRO)|DIETARY_SUPPLEMENT: milk fat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of 2% Chlorhexidine Gluconate-Impregnated Bath Cloths to Prevent MRSA Colonization in Complex Continuing Care
Status: COMPLETED
Conditions: Staph Aureus Methicillin Resistant Colonization
Interventions: DRUG: CHG antiseptic body cleanser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of Stellate Ganglion Block for Prevention of Atrial Fibrillation
Status: RECRUITING
Conditions: Atrial Fibrillation
Interventions: PROCEDURE: Stellate ganglion block|DRUG: Bupivacaine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study to Evaluate the Safety and Activity of BB3 to Treat Heart Attack
Status: TERMINATED
Conditions: Myocardial Infarction
Interventions: DRUG: BB3|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Of Selective Cyclin Dependent Kinase Inhibitor P1446A-05 In Subjects With Advanced Refractory Malignancies
Status: COMPLETED
Conditions: Solid Tumor|Hematologic Malignancy
Interventions: DRUG: P1446A-05
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Similar Outcomes of Vital Pulp Therapy Using Mineral Trioxide Aggregate or Biodentine™
Status: UNKNOWN
Conditions: Deep Caries|Reversible Pulpitis|Irreversible Pulpitis
Interventions: OTHER: Biodentine|OTHER: Mineral Trioxide Aggregate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Identification of Secreted Markers for Tumor Hypoxia in Patients With Head and Neck or Lung Cancers
Status: RECRUITING
Conditions: Head and Neck Cancer|Lung Cancer|Lip Cancer|Lip Neoplasms|Head and Neck Cancers
Interventions: PROCEDURE: Tumor biopsy|PROCEDURE: Phlebotomy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pyronaridine in Acute Lymphoblastic Leukemia (ALL) and Acute Myeloid Leukemia (AML)
Status: UNKNOWN
Conditions: Acute Myeloid Leukemia (AML)|Acute Lymphoblastic Leukemia (ALL)
Interventions: DRUG: Pyronaridine Tetraphosphate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Pharmacokinetic Interaction Between Fimasartan and Atorvastatin in Healthy Male Volunteers
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Fimasartan|DRUG: Atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: CIMAvax Vaccine, Nivolumab, and Pembrolizumab in Treating Patients With Advanced Non-small Cell Lung Cancer or Squamous Head and Neck Cancer
Status: RECRUITING
Conditions: Advanced Head and Neck Squamous Cell Carcinoma|Lung Non-Small Cell Carcinoma|Metastatic Lung Non-Small Cell Carcinoma|PD-L1 Positive|Recurrent Head and Neck Squamous Cell Carcinoma|Stage III Cutaneous Squamous Cell Carcinoma of the Head and Neck AJCC v8|Stage III Lung Cancer AJCC v8|Stage IIIA Lung Cancer AJCC v8|Stage IIIB Lung Cancer AJCC v8|Stage IIIC Lung Cancer AJCC v8|Stage IV Cutaneous Squamous Cell Carcinoma of the Head and Neck AJCC v8|Stage IV Lung Cancer AJCC v8|Stage IVA Lung Cancer AJCC v8|Stage IVB Lung Cancer AJCC v8|Unresectable Lung Non-Small Cell Carcinoma|Advanced Squamous Non-Small Cell Lung Carcinoma
Interventions: OTHER: Laboratory Biomarker Analysis|BIOLOGICAL: Nivolumab|BIOLOGICAL: Pembrolizumab|BIOLOGICAL: Recombinant Human EGF-rP64K/Montanide ISA 51 Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Physiologic Comparison of Two Approaches to Treating Peripheral Neuropathy
Status: RECRUITING
Conditions: Peripheral Neuropathy With Type 2 Diabetes
Interventions: OTHER: Intraneural Facilitation Therapy Treatment|OTHER: Standard Physical Therapy Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Monopolar Dielectric Diathermy by Radiofrequency and Therapeutic Exercise in Patients With Chronic Low Back Pain.
Status: COMPLETED
Conditions: Chronic Pain
Interventions: OTHER: Experimental: monopolar dielectric diathermy and supervised therapeutic exercise|OTHER: Active Comparator: Supervised therapeutic exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Glucose/Insulin Clamp on Solid Organ Transplant (Liver, Kidney, Pancreas and Heart) on Cadaveric Donors
Status: UNKNOWN
Conditions: Complication of Transplanted Organ, Nos
Interventions: OTHER: Hyperinsulinemic/normoglycemic clamp
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Valproic Acid in Treating Patients With Previously Treated Non-Hodgkin Lymphoma, Hodgkin Lymphoma, or Chronic Lymphocytic Leukemia
Status: UNKNOWN
Conditions: Leukemia|Lymphoma
Interventions: DRUG: valproic acid|GENETIC: western blotting|OTHER: laboratory biomarker analysis|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Changes in Cardiovascular Hemodynamics During Peritoneal Dialysis
Status: TERMINATED
Conditions: Peritoneal Dialysis
Interventions: DRUG: Icodextrin (dialysate)|DRUG: Physioneal (dialysate) 1.36% and 2.27%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Efficacy of 14-day Concomitant Therapy:Clarithromycin vs.Levofloxacin in Eradication of H.Pylori
Status: WITHDRAWN
Conditions: Helicobacter Pylori Gastrointestinal Tract Infection
Interventions: DRUG: Clarithromycin 500Mg Oral Tablet|DRUG: Levofloxacin 500Mg Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Neuromuscular Exercises Training on Physical Activity, Functionality and Balance in Knee Osteoarthritis
Status: COMPLETED
Conditions: Exercise|Osteoarthritis
Interventions: BEHAVIORAL: Neuromuscular Exercises|BEHAVIORAL: Conventional Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Imaging the Effects of Zolpidem and Alprazolam in Healthy Volunteers at 3T
Status: UNKNOWN
Conditions: Psychotropic Drugs Effects
Interventions: DRUG: Zolpidem|DRUG: Alprazolam|DRUG: Caffeine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Gut Priming With Oral Bovine Colostrum for Preterm Neonates; Randomized Control Trial
Status: COMPLETED
Conditions: Late Onset Neonatal Sepsis|Necrotizing Enterocolitis of Newborn|Feeding; Difficult, Newborn
Interventions: DIETARY_SUPPLEMENT: Bovine colostrum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Multicenter, Randomized, Parallel, Two-Period, Non-Inferiority Study of EurofarmavsAlenia in Asthma and COPD Treatment
Status: RECRUITING
Conditions: Asthma Copd
Interventions: DRUG: Alenia® 12mcg + 400mcg / Alenia® 6mcg + 200mcg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fast Track in Open Colonic Surgery - A Multicentric Randomized Controlled Trial
Status: TERMINATED
Conditions: Elective Colectomie|Median Laparotomie
Interventions: PROCEDURE: Standard Care|PROCEDURE: Fast Track care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fenoldopam and Acute Renal Failure
Status: COMPLETED
Conditions: Acute Renal Failure
Interventions: DRUG: fenoldopam|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Electroclinical Features of Sudden Unexpected Death in Epilepsy (SUDEP) : a Multi-center Observational Study
Status: ENROLLING_BY_INVITATION
Conditions: Sudden Unexpected Death in Epilepsy|Near-Sudden Unexpected Death in Epilepsy
Interventions: DIAGNOSTIC_TEST: Video-Electroencephalography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Egg Consumption and Muscular Adaptations
Status: COMPLETED
Conditions: Hypertrophy
Interventions: DIETARY_SUPPLEMENT: Whole egg and resistance training|DIETARY_SUPPLEMENT: Egg whites and resistance training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Can Distance Center and Near Center Multifocal Contact Lenses Control Myopia Progression in Children?
Status: WITHDRAWN
Conditions: Myopia|Myopia, Progressive
Interventions: DEVICE: Hybrid Contact Lens
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study on the Safety and Immunogenicity of Combined Intradermal and Intravenous Administration of an Autologous mRNA Electroporated Dendritic Cell Vaccine in Patients With Previously Treated Unresectable Stage III or IV Melanoma
Status: COMPLETED
Conditions: Melanoma
Interventions: BIOLOGICAL: TriMix-DC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Electrode Belt Used for Lung Monitoring With EIT on Tidal Volume
Status: COMPLETED
Conditions: EIT Electrode Belt Stiffness|Tidal Volume Changes
Interventions: DEVICE: EIT electrode belt, spirometry
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study With IPX056 in Subjects With Spasticity Associated With Multiple Sclerosis
Status: COMPLETED
Conditions: Spasticity|Multiple Sclerosis
Interventions: DRUG: IPX056|DRUG: Baclofen IR|DRUG: Placebo IPX056|DRUG: Placebo IR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of JZP541 in Adults With Irritability Associated With Autism Spectrum Disorder
Status: TERMINATED
Conditions: Irritability Associated With Autism Spectrum Disorder|Autism Spectrum Disorder|ASD
Interventions: DRUG: JZP541|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Interaction Between Metformin and Physical Training
Status: COMPLETED
Conditions: Impaired Glucose Tolerance|Diabetes Mellitus, Type 2
Interventions: DRUG: Metformin treatment|DRUG: Placebo treatment|BEHAVIORAL: Physical training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of Therapeutic Drug Monitoring of Protease Inhibitors on Virologic Success and Tolerance of Highly Active Antiretroviral Therapy (HAART)
Status: TERMINATED
Conditions: HIV Infections
Interventions: DRUG: nelfinavir|DRUG: lopinavir/r|DRUG: indinavir|DRUG: ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of tDCS for Mild Cognitive Impairment
Status: COMPLETED
Conditions: Mild Cognitive Impairment
Interventions: DEVICE: YBand (YDT-201N)|DEVICE: sham-YBand (YDT-201N)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of Remote Ischemic Preconditioning in Heart Failure
Status: COMPLETED
Conditions: Heart Failure|Left Ventricular Dysfunction
Interventions: OTHER: Remote ischemic preconditioning|OTHER: Sham Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vaccine Therapy in Treating Patients With High-Risk Stage III or Completely Resected Metastatic Melanoma
Status: COMPLETED
Conditions: Stage IV Melanoma|Stage III Melanoma|Recurrent Melanoma
Interventions: DRUG: dendritic cell-gp100-MART-1 antigen vaccine|DRUG: sargramostim
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Trial of Roflumilast in Asthma Management (TRIM)
Status: COMPLETED
Conditions: Asthma|Obesity
Interventions: DRUG: Roflumilast 500 Mcg Oral Tablet|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Pilot Trial of the Impact of Bedside Delivery of Discharge Medications to Pediatric Patients With Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: OTHER: Discharge Medication Delivery Service
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study to Evaluate and Compare Injections of Autologous Mixed Population of Dermal Cells Into the Balding Scalp of Subjects With Hair Loss (CA-0005995)
Status: COMPLETED
Conditions: Androgenetic Alopecia|Male Pattern Baldness|Female Pattern Baldness
Interventions: BIOLOGICAL: Autologous cultured dermal and epidermal cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Use of Pitavastatin to Reduce the Risk of Cardiovascular Disease in HIV-Infected Adults
Status: COMPLETED
Conditions: HIV Infections|Cardiovascular Diseases
Interventions: DRUG: Pitavastatin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Abiraterone Acetate in Castration-Resistant Prostate Cancer Previously Treated With Docetaxel-Based Chemotherapy
Status: COMPLETED
Conditions: Prostatic Neoplasms
Interventions: DRUG: Placebo|DRUG: Abiraterone acetate|DRUG: Prednisone/prednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Proprioception and Interoception in Patients With Fibromyalgia
Status: RECRUITING
Conditions: Fibromyalgia
Interventions: OTHER: Interoceptive accuracy measurement|OTHER: Interoceptive sensibility measurement|OTHER: Interoceptive awareness measurement|OTHER: Proprioceptive accuracy measurement during postural control|OTHER: Proprioceptive accuracy measurement of the neck
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Reproduction and Survival After Cardiac Defect Repair
Status: COMPLETED
Conditions: Cardiovascular Diseases|Heart Diseases|Defect, Congenital Heart|Aortic Valve Stenosis|Transposition of Great Vessels|Ductus Arteriosus, Patent|Heart Septal Defects, Atrial|Heart Septal Defects, Ventricular|Down Syndrome|Tetralogy of Fallot|Pulmonic Stenosis|Coarctation of Aorta
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pharmacokinetics of Sulfadoxine-pyrimethamine Plus Amodiaquine for Intermittent Preventive Treatment in Children (IPTc)
Status: COMPLETED
Conditions: Malaria
Interventions: DRUG: sulfadoxine-pyrimethamine plus amodiaquine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Efficacy Nad Safety of DWP16001 Compared to Active Drug in the Treatment of Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: T2DM (Type 2 Diabetes Mellitus)
Interventions: DRUG: DWP16001 Amg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Naloxegol on Postoperative Ileus in Patients Undergoing Cardiac Surgery
Status: COMPLETED
Conditions: Postoperative Ileus (Post Cardiac Surgery Constipation)
Interventions: DRUG: Naloxegol|DRUG: inert tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Pharmacokinetics of VNRX-5133 in the Epithelial Lining Fluid of Healthy Adult Subjects
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: VNRX-5133 + cefepime
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Floatation-REST (Reduced Environmental Stimulation Therapy) for Anxiety and Depression
Status: ACTIVE_NOT_RECRUITING
Conditions: Generalized Anxiety Disorder|Social Anxiety Disorder|Panic Disorder|Agoraphobia|Posttraumatic Stress Disorder|Major Depressive Disorder
Interventions: BEHAVIORAL: Float pool|BEHAVIORAL: Float chair
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: HS-20089 in Patients With Ovarian Cancer and Endometrial Cancer
Status: RECRUITING
Conditions: Ovarian Cancer|Fallopian Tube Cancer|Primary Peritoneal Cancer|Endometrial Cancer
Interventions: DRUG: HS-20089
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare the Safety and Efficacy of a New Eye Drop Formulation With REFRESH PLUS® in Participants Following LASIK Refractive Surgery
Status: COMPLETED
Conditions: Bilateral LASIK Surgery
Interventions: DRUG: carboxymethylcellulose sodium based new eye drop formulation|DRUG: carboxymethylcellulose sodium based eye drops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: 1% Metformin in Moderate and Severe Periodontitis
Status: COMPLETED
Conditions: Periodontitis
Interventions: DRUG: Placebo gel|DRUG: 1% Metformin gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Multicenter Clinical Translational Study of "ICU-NO CRBSI" Based on Improvement Science
Status: RECRUITING
Conditions: CRBSI - Catheter Related Bloodstream Infection|Evidence-based Nursing Practice|Central Venous Catheter Related Bloodstream Infection|Central Venous Catheter Associated Bloodstream Infection|Central Line Infection|CLABSI - Central Line Associated Bloodstream Infection|Quality Improvement
Interventions: BEHAVIORAL: evidence-based intervention Plan for the Prevention of CRBSI in ICU patients
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Trial of Naltrexone and Dextromethorphan for Gulf War Illness
Status: COMPLETED
Conditions: Gulf War Illness
Interventions: DRUG: naltrexone|DRUG: Dextromethorphan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Therapeutic Evaluation of Lower-level Laser for Treating Dentinal Hypersensitivity
Status: UNKNOWN
Conditions: Dentinal Hypersensitivity
Interventions: DEVICE: A.R.C. FOX Laser-FOX Q-810nm|PROCEDURE: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment for Comorbid Social Anxiety and Alcohol Use Disorders.
Status: COMPLETED
Conditions: Alcohol Use Disorder|Social Anxiety Disorder
Interventions: BEHAVIORAL: Fully integrated treatment|BEHAVIORAL: Stand-alone Intensive Outpatient Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immediate Effects Cervicothoracic Manipulation Versus Passive Upper Trapezius Stretch
Status: COMPLETED
Conditions: Neck Pain
Interventions: OTHER: Upper Trapezius Stretch|OTHER: Cervicothoracic manipulation|OTHER: No intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of IL4Rα Monoclonal Antibody in Patients With Uncontrolled Seasonal Allergic Rhinitis.
Status: RECRUITING
Conditions: Allergic Rhinitis
Interventions: BIOLOGICAL: GR1802 injection-1|BIOLOGICAL: GR1802 injection-2|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: KBP-201 COVID-19 Vaccine Trial in Healthy Volunteers
Status: COMPLETED
Conditions: Covid19
Interventions: BIOLOGICAL: Low Dose of KBP-COVID-19|BIOLOGICAL: High Dose of KBP-COVID-19|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Macronutrients and Postprandial Vascular Function
Status: COMPLETED
Conditions: Dietary Fats|Carbohydrates|Proteins|Macronutrients|Vascular Function|Postprandial Metabolism
Interventions: OTHER: High-fat (HF-LC-LP) milkshake|OTHER: High-carbohydrate (LF-HC-LP) milkshake|OTHER: High-protein (LF-LC-HP) milkshake
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Different Bandage Interface Pressures on Breast Cancer Related Lymphedema
Status: COMPLETED
Conditions: Lymphedema of Upper Limb|Breast Cancer Lymphedema|Edema Arm
Interventions: OTHER: complex decongestive physiotherapy with low pressure compression bandage|OTHER: complex decongestive physiotherapy with high pressure compression bandage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Prospective Study Comparing Two Radiotherapy Dose/Fraction and Omitting CTVs of the Primary Tumor in Limited SCLC
Status: RECRUITING
Conditions: Small Cell Lung Cancer Limited Stage
Interventions: RADIATION: Hyperfractionated radiotherapy|RADIATION: Hypofractionated radiotherapy|DRUG: Etoposide|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of rPMS on Motor Skill Performance in Persons With a Stroke.
Status: COMPLETED
Conditions: Stroke
Interventions: OTHER: Repetitive Peripheral Magnetic Stimulation (rPMS)|OTHER: Sham Priming
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Telehealth Intervention for Ostomy Self-Management
Status: NOT_YET_RECRUITING
Conditions: Colorectal Cancer|Bladder Cancer
Interventions: BEHAVIORAL: Telehealth Intervention|OTHER: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Intervening to Improve Infant Health in Ghana
Status: COMPLETED
Conditions: Very Low Birth Weight Baby|Pneumonia
Interventions: OTHER: Cook stoves, either Biolite wood stove, or liquified petroleum gas stove plus fuel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Motexafin Gadolinium and Doxorubicin in Treating Patients With Advanced Cancer
Status: COMPLETED
Conditions: Breast Cancer|Chronic Myeloproliferative Disorders|Colorectal Cancer|Head and Neck Cancer|Leukemia|Lung Cancer|Lymphoma|Multiple Myeloma and Plasma Cell Neoplasm|Myelodysplastic/Myeloproliferative Diseases|Prostate Cancer|Small Intestine Cancer|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: doxorubicin hydrochloride|DRUG: motexafin gadolinium
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: SThe Effects of Melatonin on GERD Symptoms
Status: UNKNOWN
Conditions: Gastroesophageal Reflux Disease
Interventions: DRUG: Melatonin|OTHER: omeprazole|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CD8 PET Imaging in Metastatic Solid Tumours
Status: NOT_YET_RECRUITING
Conditions: Locally Advanced Solid Tumor
Interventions: RADIATION: 89Zr-Df-crefmirlimab PET scan|DRUG: Nivolumab|DRUG: Cetrelimab|OTHER: zirconium Zr 89 crefmirlimab berdoxam
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Post Marketing Study for the Evaluation of Predictix Antidepressant Clinician Software Support Tool in Prescribing Antidepressant Medication/s for the Treatment of Patients Suffering From Major Depressive Disorder
Status: UNKNOWN
Conditions: Major Depressive Disorder
Interventions: DEVICE: Predictix Antidepressant Software tool
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Cervical-Cranial Dry Needling vs. Orthopedic Manual Therapy for Cervicogenic Headache
Status: RECRUITING
Conditions: Cervicogenic Headache
Interventions: OTHER: Cervical-cranial dry needling|OTHER: Orthopedic manual therapy|OTHER: Thoracic Manipulation|OTHER: Exercise|OTHER: Patient Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Clinical Significance of Ovarian Function Detection and Protection in Fertility Preservation Surgery for Ovarian Malignancy
Status: UNKNOWN
Conditions: Fertility Preservation Surgery|Ovarian Malignancy
Interventions: DRUG: GnRHa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of a Triptorelin 6-month Formulation in Patients With Advanced Prostate Cancer
Status: COMPLETED
Conditions: Prostatic Neoplasm
Interventions: DRUG: triptorelin embonate (INN)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized, Double Blind, Placebo-controlled Study to Evaluate the Efficacy of Lavandula Angustifolia Containing Nasal Spray Medical Device in Preventing Deterioration of COVID-19 in Symptomatic Patients
Status: UNKNOWN
Conditions: COVID-19 Infection
Interventions: DEVICE: Nasal Spray Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An Study of Patidegib Topical Gel, 2%, for the Reduction of Disease Burden of Persistently Developing Basal Cell Carcinomas in Patients With Non-Gorlin High Frequency BCC
Status: TERMINATED
Conditions: Recurrent Basal Cell Carcinoma
Interventions: DRUG: Patidegib Topical Gel, 2%|DRUG: Patidegib Topical Gel, Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Open Abdomen: Vacuum Pack Versus Sylo Bag and Mesh Protocol
Status: COMPLETED
Conditions: Open Abdomen|Temporary Abdominal Closure Mechanisms
Interventions: DEVICE: Vacuum Pack|DEVICE: Double Sylo Bag - Mesh Protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Analgesia for Laparotomy in Cancer Patients: Quadratus Lumborum Block
Status: COMPLETED
Conditions: Cancer
Interventions: OTHER: Quadratus lumborum block|OTHER: Transversus abdominis plane block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Tolerability of, and Adherence to, Dolutegravir With Co-formulated Tenofovir-emtricitabine for HIV Non-occupational Post-exposure Prophylaxis
Status: COMPLETED
Conditions: Human Immunodeficiency Virus
Interventions: DRUG: dolutegravir 50 mg (one tablet daily)|DRUG: emtricitabine-tenofovir 300/200 mg (one tablet daily)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparison of Alveolar Macrophages in Individuals With COPD Versus Smokers With Normal Pulmonary Function
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive|Lung Diseases, Obstructive
Interventions: PROCEDURE: Blood drawing|PROCEDURE: Bronchoalveolar lavage during indicated bronchoscopy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Patient Perceptions Following a Single Session of Simulated or Genuine HVLA Manual Chiropractic Adjustments
Status: COMPLETED
Conditions: Subluxation
Interventions: PROCEDURE: Chiropractic adjustment|PROCEDURE: Sham adjustment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Efficacy and Safety of Desmopressin Melt for the Treatment of Nocturia
Status: COMPLETED
Conditions: Nocturia
Interventions: DRUG: desmopressin acetate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Immediate Effect of Electrical Noise Stimulation on Neuromuscular Adaptation of Balance
Status: UNKNOWN
Conditions: Balanced|Electroencephalography|Electromyography
Interventions: DEVICE: electrical noise stimulation|DEVICE: Sham stimulation|DEVICE: Foam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Serologic Surveillance for SARS-CoV-2 (COVID-19) in a Prospective Cohort of Health Care Workers
Status: UNKNOWN
Conditions: COVID-19|SARS-CoV 2|Health Personnel
Interventions: DIAGNOSTIC_TEST: Serologic SARS-CoV-2 screening
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Changes in Oral Vitamin K Intake for Optimization of Chronic Oral Anticoagulation: A Randomized Trial
Status: COMPLETED
Conditions: Blood Coagulation Disorders
Interventions: BEHAVIORAL: Changes on Oral Vitamin K Intake
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of Etafilcon A Contact Lenses Using a Novel Manufacturing Technology
Status: COMPLETED
Conditions: Visual Acuity
Interventions: DEVICE: 1-DAY ACUVUE® MOIST|DEVICE: 1-DAY ACUVUE® MOIST
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: End Tidal Anesthetic Concentration in Different Anesthesia Techniques Where Depth of Anesthesia Adjusted With Entropy
Status: COMPLETED
Conditions: General Anesthesia|Inhalation; Gas
Interventions: DRUG: Bupivacaine|DRUG: Sevoflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Combination Chemotherapy in Treating Patients With Burkitt's Lymphoma or Burkitt's Leukemia
Status: COMPLETED
Conditions: Leukemia|Lymphoma
Interventions: BIOLOGICAL: filgrastim|DRUG: cyclophosphamide|DRUG: cytarabine|DRUG: doxorubicin hydrochloride|DRUG: etoposide|DRUG: ifosfamide|DRUG: leucovorin calcium|DRUG: methotrexate|DRUG: vincristine sulfate|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Therapy With Myo-inositol and Folic Acid Versus Myo-inositol Alone
Status: COMPLETED
Conditions: Polycystic Ovary Syndrome|Hirsutism|Menstrual Irregularity
Interventions: DRUG: myo-inositol 1500 gr|DRUG: myo-inositol 2000 gr + folic acid 200 mcg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Hormone Therapy on the Immune Systems of Postmenopausal Women With Chronic Infections
Status: COMPLETED
Conditions: Atherosclerosis|Chlamydia Infections|Cytomegalovirus Infections|Pneumonia, Bacterial|Postmenopause
Interventions: DRUG: Estrogen therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Phase II Clinical Trial of Interleukin-2 in AD
Status: RECRUITING
Conditions: Alzheimer Disease
Interventions: DRUG: Interleukin-2|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Proof-of-Concept Study of Faricimab (RO6867461) in Participants With Choroidal Neovascularization (CNV) Secondary to Age-Related Macular Degeneration (AMD)
Status: COMPLETED
Conditions: Choroidal Neovascularization
Interventions: DRUG: Faricimab|DRUG: Ranibizumab|DRUG: Sham Procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Rocuronium + Sugammadex vs. Succinylcholine + Cisatracurium + Neostigmine/Atropine in Obese Participants (MK-8616-104)
Status: WITHDRAWN
Conditions: Neuromuscular Blockade
Interventions: DRUG: Rocuronium|DRUG: Sugammadex|DRUG: Cisatracurium|DRUG: Neostigmine/Atropine|DRUG: Succinylcholine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Effect of Short Message Service Intervention on Stent Removal/Exchange Adherence in Patients With Benign Pancreaticobiliary Diseases
Status: COMPLETED
Conditions: Short Message Service|Adherence|Stent Exchange|ERCP|Biliary Stricture
Interventions: OTHER: SMS reminder|OTHER: Conventional reminder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Autologous Tumor Infiltrating Lymphocytes MDA-TIL in Treating Patients With Recurrent or Refractory Ovarian Cancer, Colorectal Cancer, or Pancreatic Ductal Adenocarcinoma
Status: TERMINATED
Conditions: Malignant Solid Neoplasm|Metastatic Colorectal Adenocarcinoma|Metastatic Ovarian Carcinoma|Metastatic Pancreatic Ductal Adenocarcinoma|Platinum-Resistant Ovarian Carcinoma|Recurrent High Grade Ovarian Serous Adenocarcinoma|Recurrent Ovarian Carcinosarcoma|Refractory Colorectal Carcinoma|Stage IV Colorectal Cancer AJCC v8|Stage IVA Colorectal Cancer AJCC v8|Stage IVB Colorectal Cancer AJCC v8|Stage IVC Colorectal Cancer AJCC v8
Interventions: BIOLOGICAL: Autologous Tumor Infiltrating Lymphocytes MDA-TIL|DRUG: Cyclophosphamide|DRUG: Fludarabine|BIOLOGICAL: Interleukin-2|OTHER: Quality-of-Life Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Listening to Holy Quran Recital on the Incidence of Delirium Post-CABG
Status: NOT_YET_RECRUITING
Conditions: Coronary Artery Disease|Coronary Artery Bypass Graft Surgery|Delirium, Postoperative
Interventions: OTHER: Holy Quran Recital
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Intragastric Quinine, Alone or Combined With L-leucine, on Postprandial Glycaemic Control
Status: RECRUITING
Conditions: Healthy
Interventions: OTHER: Quinine|OTHER: L-leucine|OTHER: Combination of quinine and L-leucine|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Tapioca Starch Stimutex AS, Aloe Barbadensis, Rose Hip Oil, Allantoin Comparing With Topical 1% Hydrocortisone Cream
Status: COMPLETED
Conditions: Intertrigo
Interventions: DRUG: Liquid powder|DRUG: Hydrocortisone cream 1%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Registry to Evaluate the ROX COUPLER in Patients With Resistant or Uncontrolled Hypertension
Status: COMPLETED
Conditions: Hypertension|Blood Pressure, High|Blood Pressure, Resistant|Blood Pressure, Uncontrolled
Interventions: DEVICE: ROX COUPLER
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of UHAC 62 XX Tablets Compared With Capsules in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: UHAC 62 XX tablet|DRUG: UHAC 62 XX capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Apatinib Combined With Albumin-Bound Paclitaxel for Treatment of Advanced Triple Negative Breast Cancer
Status: UNKNOWN
Conditions: Advanced Triple Negative Breast Cancer
Interventions: DRUG: Apatinib Mesylate|DRUG: Albumin-Bound Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Thoracic Spine Manipulation in Individuals With Non-traumatic Cervical Pain
Status: UNKNOWN
Conditions: Neck Pain|Cervical Pain
Interventions: PROCEDURE: Manual Manipulation|PROCEDURE: Mobilization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pathogenesis of Kidney Disease in Type 1 Diabetes: a Modern Kidney Biopsy Cohort (The PANDA Study)
Status: RECRUITING
Conditions: Type 1 Diabetes|Diabetic Kidney Disease|Diabetes Complications|Diabetic Nephropathies|Autoimmune Diabetes
Interventions: DRUG: Aminohippurate Sodium Inj 20% Diagnostic aid/agent used to measure effective renal plasma flow (ERPF)|DRUG: Iohexol Inj 300 MG/ML Diagnostic aid/agent used to measure glomerular filtration rate (GFR)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Dietary Approaches for Cardiometabolic Health
Status: COMPLETED
Conditions: Obesity, Abdominal|Dyslipidemias|Insulin Resistance|Blood Pressure|Weight Loss
Interventions: BEHAVIORAL: Time Restricted Eating|BEHAVIORAL: Standard Cardiometabolic Health Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Neodolpasse® Infusion Solution Versus Diclofenac 75 mg Infusion in the Treatment of Postoperative Pain After Elective Knee Surgery
Status: COMPLETED
Conditions: Pain, Postoperative|Analgesic Adverse Reaction|Cruciate Ligament Rupture
Interventions: DRUG: Neodolpasse|DRUG: Diclofenac|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Strength of Handgrip in Patients With Pulmonary Artery Hypertension
Status: UNKNOWN
Conditions: Pulmonary Hypertension
Interventions: DIAGNOSTIC_TEST: Handgrip strength test
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluate the Efficacy and Safety of TGR-1202 in Participants With Chronic Lymphocytic Leukemia Who Are Intolerant to Prior Therapy
Status: TERMINATED
Conditions: Chronic Lymphocytic Leukemia
Interventions: DRUG: Umbralisib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stroke and Cerebrovascular Diseases Registry
Status: COMPLETED
Conditions: Stroke|Acute Stroke|Acute Brain Injury|Ischemic Stroke|Hemorrhagic Stroke|Transient Ischemic Attack|Subarachnoid Hemorrhage|Cerebral Ischemia|Cerebral Infarction|Cerebral Stroke|Venous Sinus Thrombosis, Cranial
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: High-Intensity Focused Electromagnetic (HIFEM) Field Device in Women After Childbirth
Status: COMPLETED
Conditions: Muscle Tone Increased
Interventions: DEVICE: High-Intensity Focused Electromagnetic (HIFEM) Field Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of D005 Vaginal Mousse on Bacterial Vaginosis
Status: ACTIVE_NOT_RECRUITING
Conditions: Bacterial Vaginosis &#X7C; Vaginal &#X7C; Microbiology
Interventions: DEVICE: D005 Vaginal Mousse|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Non-pharmacological Prevention of Postoperative Delirium by Occupational Therapy Teams
Status: COMPLETED
Conditions: Postoperative Delirium|Aging Disorder
Interventions: BEHAVIORAL: Occupational therapy intervention|BEHAVIORAL: Standard non-pharmacological prevention intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Patient Experience in Peripheral Venipuncture With and Without Ultrasound
Status: COMPLETED
Conditions: Peripheral Venous Catheterization|Ultrasonography|Pain
Interventions: DEVICE: Ultrasound-guided peripheral venipuncture|DEVICE: Conventional peripheral venipuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Betaglucin 0.2% Versus Imiquimod 5% in Treatment of Ano-genital Warts: Combined Results From Triple Blind Controlled Study
Status: UNKNOWN
Conditions: Genital Wart Virus Infection
Interventions: DRUG: Betaglucin soluble gel 0.2%|DRUG: Imiquimod 5% cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Short-Term Anticoagulation Versus Antiplatelet Therapy for Preventing Device Thrombosis Following Left Atrial Appendage Closure
Status: RECRUITING
Conditions: Left Atrial Appendage Closure|Thrombosis|Stroke|TIA|Bleeding
Interventions: DRUG: Rivaroxaban, dabigatran, apixaban, or edoxaban|DRUG: Clopidogrel -75 mg/day|DRUG: Low dose aspirin -80 to 125 mg/day-
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Bioimpedence and Arterial Function Monitoring at Birth and in Infants
Status: RECRUITING
Conditions: Arterial Stiffness|Fetal Growth Retardation|Small for Gestational Age at Delivery|Pre-Eclampsia
Interventions: DEVICE: Vicorder: pulse wave velocity, pulse wave analysis, stroke volume, cardiac output|DEVICE: NICaS|DEVICE: Echocardiography and ultrasound of arteries
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p