pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Predicting Development of Diabetes Mellitus in Patients Undergoing Allogeneic Stem Cell Transplant
Status: TERMINATED
Conditions: Diabetes Mellitus|Malignant Neoplasm
Interventions: PROCEDURE: assessment of therapy complications|PROCEDURE: assessment of therapy complications|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Abraxane® With or Without Mifepristone for Advanced, Glucocorticoid Receptor-Positive, Triple-Negative Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Mifepristone|OTHER: Placebo|DRUG: Nab-Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Analgesic Effect of a New Analgesic Based Gel(Douloff) Versus Oral Paracetamol in Acute Soft Injuries
Status: NOT_YET_RECRUITING
Conditions: Analgesia
Interventions: DRUG: Douloff|DRUG: paracetamol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Effects of Polyphenolic-rich Dark Chocolate/Cocoa and Almonds on Cardiovascular Disease Risk Factors
Status: COMPLETED
Conditions: Cardiovascular Disease
Interventions: OTHER: Healthy American Control Diet|OTHER: Dark Chocolate/Cocoa Diet|OTHER: Almond Diet|OTHER: Dark Chocolate/Cocoa + Almond Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Comparison of Testicular Volume and Blood Flow in Patients With Inguinal Hernia, Hydrocele, and Cord Cyst
Status: COMPLETED
Conditions: Inguinal Hernia Repair
Interventions: DEVICE: Color Doppler Ultrasound|DEVICE: Color Doppler Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Citrate Salts for Stone-free Result After Flexible Ureterorenoscopy for Inferior Calyx Calculi
Status: UNKNOWN
Conditions: Urolithiasis|Calyx; Calculus
Interventions: DIETARY_SUPPLEMENT: Potassium and magnesium citrate|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Evaluating Safety and Immunogenicity of 23-Valent Pneumococcal Polysaccharide Vaccine With Influenza Vaccine in Children and Adults
Status: COMPLETED
Conditions: Pneumococcal Infection|Influenza
Interventions: BIOLOGICAL: 23-valent pneumococcal polysaccharide vaccine|BIOLOGICAL: trivalent influenza vaccine|BIOLOGICAL: 23vPPV+TIV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Broad Multi-histology Phase II Study of the Multi-Kinase Inhibitor R935788 (Fostamatinib Disodium) in Advanced Colorectal, Non-small Cell Lung, Head and Neck Hepatocellular and Renal Cell Carcinomas, and Pheochromocytoma and Thyroid Tumors (Multi-H...
Status: COMPLETED
Conditions: Head and Neck Neoplasms|Pheochromocytoma|Colorectal Neoplasms|Carcinoma, Non-Small-Cell Lung|Carcinoma, Renal Cell
Interventions: DRUG: Fostamatinib disodium
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radiofrequency Ablation Accompanied With Spontaneous Sorafenib in Early to Intermediate Stage HCC
Status: UNKNOWN
Conditions: HCC
Interventions: PROCEDURE: radiofrequency ablation plus Sorafenib|PROCEDURE: Radiofrequency ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Open Label Trial Studying the Safety and Effectiveness of ILUVIEN® (190μg) in Children and Adolescents, Who Have Recurrent Non-infectious Uveitis Affecting the Posterior Segment of the Eye.
Status: RECRUITING
Conditions: Non-infectious Uveitis Affecting the Posterior Segment of the Eye
Interventions: DRUG: fluocinolone acetonide 190 micrograms
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: CD8 Depleted, Non-engrafting, HLA Mismatched Unrelated Infusion With MDS and Secondary AML
Status: ACTIVE_NOT_RECRUITING
Conditions: Myelodysplastic Syndromes|Secondary Acute Myeloid Leukemia
Interventions: BIOLOGICAL: CD8 Depleted, Non-engrafting,HLA mismatched unrelated donor lymphocytes|DRUG: Standard of Care Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Management of Coagulopathy During Orthotopic Liver Transplantation. Comparison Between ROTEM-based Management and Standard Biological Assessment.
Status: COMPLETED
Conditions: Liver Transplantation
Interventions: PROCEDURE: Conventional coagulation profile Analysis|PROCEDURE: Rotem analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of Mobile-Based Education on Postoperative Recovery and Quality of Life in Thyroidectomy Patients
Status: NOT_YET_RECRUITING
Conditions: Thyroid Diseases|Healthy Lifestyle|Thyroid
Interventions: OTHER: Mobile based education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of GSK1120212 Plus Gemcitabine vs Placebo Plus Gemcitabine in Metastatic Pancreatic Cancer
Status: COMPLETED
Conditions: Cancer
Interventions: DRUG: GSK1120212|DRUG: Gemcitabine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PEP-CMV Vaccine Targeting CMV Antigen to Treat Newly Diagnosed Pediatric HGG and DIPG and Recurrent Medulloblastoma
Status: RECRUITING
Conditions: High Grade Glioma|Diffuse Intrinsic Pontine Glioma|Recurrent Medulloblastoma
Interventions: BIOLOGICAL: PEP-CMV|DRUG: Temozolomide|BIOLOGICAL: Tetanus Diphtheria Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safe and Effective Shoulder Exercise Training in Manual Wheelchair Users With SCI
Status: COMPLETED
Conditions: Shoulder Pain|Spinal Cord Injury
Interventions: BEHAVIORAL: Shoulder pain and SCI|BEHAVIORAL: Shoulder pain and able bodies
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Application Value of da Vinci Linear Cutting Stapler SureForm in Robotic Anus Preserving Surgery for Rectal Cancer
Status: RECRUITING
Conditions: Rectal Cancer|Robotic|Anastomotic Leak|Laparoscopic
Interventions: DEVICE: Surform
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of LY3016859 in Participants With Diabetic Nephropathy
Status: COMPLETED
Conditions: Diabetic Nephropathy
Interventions: DRUG: Placebo|DRUG: LY3016859
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Single-Ascending and Repeated Dose Study of LY3849891 in Participants With Nonalcoholic Fatty Liver Disease
Status: RECRUITING
Conditions: Non-Alcoholic Fatty Liver Disease
Interventions: DRUG: LY3849891|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Trial of Vitamin D Supplements to Raise Calcidiol Levels of Pregnant Women in Mongolia
Status: COMPLETED
Conditions: Pregnancy|Vitamin D Deficiency
Interventions: DIETARY_SUPPLEMENT: 600 IU Vitamin D3 in prenatal vitamin|DIETARY_SUPPLEMENT: 2000 IU Vitamin D3 in prenatal vitamin|DIETARY_SUPPLEMENT: 4000 IU Vitamin D3 in prenatal vitamin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Accuracy of 3DPrinted Windowed Bracket- Positioning Guide Compared To Thermoformed Indirect Bonding Tray
Status: UNKNOWN
Conditions: Inaccurate Transfer and Bond Failure of Conventional Indirect Bonding Tray|Accuracy of Bracket Transfer and Bond Failure Rate of Digitally Printed Transfer Tray With Windows and Conventional Thermoformed Transfer Tray
Interventions: DEVICE: 3DPrinted Windowed Bracket- Positioning tray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: ICG- Livertest Versus New Biomarkers as Prognostic Markers in Critically Ill ICG- Livertest Versus New Biomarkers as Prognostic Markers in Critically Ill
Status: UNKNOWN
Conditions: Critically Ill Patients
Interventions: PROCEDURE: Observational
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Group Cognitive Behavioural Therapy (CBT) For Perinatal Anxiety
Status: COMPLETED
Conditions: Perinatal Anxiety
Interventions: BEHAVIORAL: Group Cognitive Behaviour Therapy for Perinatal Anxiety (CBT-PA)|OTHER: No treatment (waitlist control)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: OCT Angiography and NRAI in Dementia
Status: RECRUITING
Conditions: Alzheimer Disease|Dementia|Mild Cognitive Impairment
Interventions: DEVICE: Optical Coherence Tomography Angiography (OCTA) Imaging|DEVICE: Noninvasive Retinal Amyloid Imaging (NRAI)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effectiveness of Preoperative Antiseptic Preparation in Transnasal Skull Base Surgery
Status: COMPLETED
Conditions: Meningitis and Sinusitis in Transnasal Surgery
Interventions: PROCEDURE: Preoperative Antiseptic preparation prior to transnasal skull base surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Investigating the Effects of Mikei® Red Reishi Essence EX on the Immune System of Prostate Cancer Patients and Patients With Non-cancerous Conditions of the Prostate
Status: WITHDRAWN
Conditions: Prostate Cancer
Interventions: DIETARY_SUPPLEMENT: Mikei Red Reishi Essence EX|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: First-in-Human Single Ascending and Multiple Dose of GLPG0634
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: GLPG0634|DRUG: placebo|DRUG: GLPG0634|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Olutasidenib for the Treatment of Patients With IDH1 Mutated AML, MDS or CMML After Donor Hematopoietic Cell Transplant
Status: RECRUITING
Conditions: Acute Myeloid Leukemia|Chronic Myelomonocytic Leukemia|Myelodysplastic Syndrome
Interventions: PROCEDURE: Biospecimen Collection|DRUG: Olutasidenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase II Trial If Nivolumab, Lenalidomide and Dexamethasone in High Risk Smoldering Myeloma
Status: COMPLETED
Conditions: Smoldering Multiple Myeloma
Interventions: DRUG: Nivolumab|DRUG: Lenalidomide|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rapid Test and Treat Dolutegravir Plus Lamivudine Study in Newly Diagnosed Human Immunodeficiency Virus (HIV)-1 Infected Adults
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Dolutegravir + Lamivudine FDC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of HR20013 for Injection in Patients With Malignant Solid Tumors
Status: COMPLETED
Conditions: Prevention of Nausea and Vomiting Caused by Highly Emetogenic Chemotherapy
Interventions: DRUG: HR20013 for injection；dexamethason
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Bioequivalence of Two Different Polymorphs of Dabigatran Etexilate in Healthy Male and Female Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Dabigatran etexilate polymorph II|DRUG: Dabigatran etexilate polymorph I
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Carisbamate as a Potential Treatment for Alcohol Dependence
Status: COMPLETED
Conditions: Alcohol Dependence|Alcohol Abuse|Substance Abuse
Interventions: DRUG: Carisbamate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Comparison of Full-Field Digital Mammography With Digital Breast Tomography for Screening Call-Back Rates
Status: UNKNOWN
Conditions: Breast Neoplasms
Interventions: DEVICE: Screening Tomosynthesis|DEVICE: Diagnostic Tomosynthesis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: RNS® System Feasibility Study
Status: COMPLETED
Conditions: Epilepsy
Interventions: PROCEDURE: RNS® System implantation|DEVICE: RNS® System responsive stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Validation of ERTugliflozin for Inhibiting Cardiac Fibrosis Using Cardiac MRI and Laboratory Parameters in Korean Heart Failure Patients With Nonischemic Cardiomyopathy(VERTICAL)
Status: UNKNOWN
Conditions: Heart Failure With Nonischemic Cardiomyopathy
Interventions: DRUG: Ertugliflozin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Repetitive Transcranial Magnetic Stimulation(rTMS) Regulating Slow-wave to Delay the Progression of Parkinson's Disease
Status: RECRUITING
Conditions: Parkinson's Disease
Interventions: DEVICE: rTMS real stimulation stage1|DEVICE: rTMS shame stimulation stage1|DEVICE: rTMS real stimulation stage 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multiple Ascending Dose Study in Subjects With Type 2 Diabetes
Status: TERMINATED
Conditions: Diabetes Mellitus
Interventions: DRUG: AMG 876
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Gas Kinetics and Metabolism in Anesthesia During Non Steady State
Status: WITHDRAWN
Conditions: Anesthetized Healthy Patients (ASA 1 or 2) in the Supine Position, Excluding Head, Neck and Head Surgeries|Anesthetized Patient With Severe Systemic Disease (ASA 3 or 4)
Interventions: DEVICE: connection of measuring device to anesthesia circuit|PROCEDURE: drawing of blood sample through an arterial line, placed according to clinical criteria by primary anesthesia team|PROCEDURE: changing operating room bed position (head down and up position)|PROCEDURE: adding PEEP during anesthesia|PROCEDURE: placement of esophageal Doppler for cardiac output measurements|DEVICE: Humidity sensor|DEVICE: A mixing chamber (bymixer)|DEVICE: Pneumotachometer cuvette|DEVICE: Mass spectrometer sampling port
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effectiveness of Myofascial Release Versus Manual Lymphatic Drainage After Breast Cancer Surgery
Status: COMPLETED
Conditions: Fibromyalgia
Interventions: OTHER: Lymphatic Drainage|OTHER: Myofascial Release
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transferring Speed of Processing Gains to Everyday Cognitive Tasks After Stroke
Status: RECRUITING
Conditions: Stroke|Cognitive Dysfunction
Interventions: BEHAVIORAL: Speed of Processing Training|BEHAVIORAL: Instrumental Activities of Daily Living In-lab Training|BEHAVIORAL: Cognitive Transfer Packagke|BEHAVIORAL: Family Caregiver Coaching|BEHAVIORAL: Follow-up Phone Calls|BEHAVIORAL: Healthy Lifestyle In-lab Training|BEHAVIORAL: Healthy Lifestyle Transfer Package
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Radspherin® in Colorectal Carcinoma Subjects With Peritoneal Carcinomatosis Treated With HIPEC
Status: ACTIVE_NOT_RECRUITING
Conditions: Peritoneal Carcinoma|Colorectal Carcinoma
Interventions: DRUG: Radspherin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of ACE-Inhibition on Microvascular Function in Women With Assessed Microvascular Dysfunction
Status: COMPLETED
Conditions: Microvascular Angina
Interventions: DRUG: Ramipril (ACE-inhibitor)|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of the Pharmacokinetics of Circadin® in Children With Neurodevelopmental Disorders and Sleep Disturbances
Status: COMPLETED
Conditions: Sleep Problems
Interventions: DRUG: Circadin 2 mg|DRUG: Circadin 10 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Scripps Evaluation of Antiplatelet Therapies for Intermediate Duration With the Endeavor Stent (Seaside)
Status: COMPLETED
Conditions: Coronary Artery Disease|Coronary Thrombosis
Interventions: DEVICE: Medtronic Endeavor Stent|DRUG: Reduced duration (6 months) DAPT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics, Safety & Tolerability of ZD4054 (Zibotentan) in Subjects With Normal, Mild, Moderate and Severe Hepatic Impairment
Status: COMPLETED
Conditions: Hepatic Impairment
Interventions: DRUG: ZD4054
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics of AUX-001 40mg Once-daily in Healthy Subjects Under Fasting and Fed Conditions
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Stable Angina
Interventions: DRUG: AUX-001 40mg once-daily
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose-escalation Study of GSK2330672 in Japanese Healthy Male Volunteers
Status: COMPLETED
Conditions: Cholestasis
Interventions: DRUG: GSK2230672|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: IL-32 Levels in Patients With Chronic Periodontitis
Status: COMPLETED
Conditions: Periodontitis
Interventions: OTHER: nonsurgical periodontal treatment|OTHER: Gingival crevicular fluid and saliva collection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Helicobacter Pylori Eradication After Subtotal Gastrectomy on Survival Rate of Gastric Cancer Patients: Retrospective Study
Status: COMPLETED
Conditions: Gastric Cancer
Interventions: COMBINATION_PRODUCT: Helicobacter pylori eradication (combination therapy)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Dose-escalation Study to Assess the Safety, Tolerability, and Pharmacokinetics of GDC-0032 in Combination With Docetaxel or With Paclitaxel in Patients With HER2-negative Locally Recurrent or Metastatic Breast Cancer or Non-small Cell Lung Cancer
Status: COMPLETED
Conditions: Breast Cancer, Non-small Lung Cancer
Interventions: DRUG: Docetaxel|DRUG: GDC-0032|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Investigate Safety, Reactogenicity and Immunogenicity of VIR-1388 Compared With Placebo in Participants Without HIV
Status: RECRUITING
Conditions: HIV I Infection
Interventions: BIOLOGICAL: VIR-1388|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Microbiome Fructan Metabolism and Symptoms in Childhood IBS
Status: COMPLETED
Conditions: Irritable Bowel Syndrome (IBS)
Interventions: OTHER: Fructan|OTHER: Maltodextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Bioequivalence Study of Temozolomide in Patients With Primary Tumors of the Central Nervous System
Status: COMPLETED
Conditions: Brain Neoplasms, Malignant, Primary
Interventions: DRUG: Temozolomide|DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gout Dose Response Study
Status: COMPLETED
Conditions: Hyperuricemia
Interventions: DRUG: RDEA594|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Granulocyte Colony-Stimulating Factor Plus Recombinant Erythropoietin Plus Zidovudine in Patients With AIDS or AIDS-Related Complex
Status: COMPLETED
Conditions: HIV Infections|Cytopenias
Interventions: DRUG: Filgrastim|DRUG: Epoetin alfa|DRUG: Zidovudine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Intratumoral Injection PF-3512676 Plus Local Radiation in Low-Grade B-Cell Lymphomas
Status: COMPLETED
Conditions: Lymphoma, Non-Hodgkin|Lymphoma|Lymphomas: Non-Hodgkin Follicular / Indolent B-Cell|Lymphomas: Non-Hodgkin
Interventions: DRUG: PF-3512676|RADIATION: Local radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bortezomib and Sorafenib Tosylate in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Myeloid Leukemia|Leukemia Cutis|Myeloid Neoplasm|Myeloid Sarcoma
Interventions: DRUG: Asparaginase|DRUG: Bortezomib|DRUG: Cytarabine|DRUG: Daunorubicin Hydrochloride|DRUG: Etoposide|OTHER: Laboratory Biomarker Analysis|DRUG: Mitoxantrone Hydrochloride|OTHER: Pharmacological Study|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration|DRUG: Sorafenib Tosylate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Expression of Matrix Metalloproteinase 13, Tissue Inhibitor of Metalloproteinases 3, and Calcium-sensing Receptor in Human Trabecular Meshwork
Status: COMPLETED
Conditions: Open-angle Glaucoma
Interventions: PROCEDURE: trabeculectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety, PK and Antiviral Activity of PGT121 Monoclonal Antibody in HIV-uninfected and HIV-infected Adults
Status: COMPLETED
Conditions: HIV Infection
Interventions: BIOLOGICAL: PGT121 3mg/kg IV|BIOLOGICAL: PGT121 10mg/kg IV|BIOLOGICAL: PGT121 30mg/kg IV|BIOLOGICAL: PGT121 3mg/kg SC|BIOLOGICAL: Placebo (0.9% Sodium Chloride Injection USP (Saline))
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Prophylactic Administration of Neulapeg (Pegteograstim) in Patients With Locally Advanced or Metastatic Pancreatic Cancer Receiving the Modified FOLFIRINOX
Status: ACTIVE_NOT_RECRUITING
Conditions: Locally Advanced Pancreatic Cancer|Metastatic Pancreatic Cancer
Interventions: DRUG: Neulapeg|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Herbal Products on Platelet Function and Clotting
Status: COMPLETED
Conditions: Platelet Function Test
Interventions: DRUG: Curcuma longa|DRUG: Angelica sinensis|DRUG: Siwu Tang|DRUG: Aspirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Quadruple Oral Combination Therapy for Type 2 Diabetes Mellitus : Glycemic Control by Thiazolidinedione (TZD) or Sodium Glucose Co-transporter 2 (SGLT-2) Inhibitor as an add-on Therapy in Type 2 Diabetes Mellitus After Failure of an Oral Triple Antidiabetic Regimen
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: TZD group|DRUG: SGLT-2 group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PDS Versus Prolene as Suture Material for Vaginal Sacrospinous Hysteropexy
Status: RECRUITING
Conditions: Pelvic Organ Prolapse|Prolapse
Interventions: PROCEDURE: sacrospinous hysteropexy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy in Treating Patients With Unresectable Locally Advanced or Metastatic Stomach Cancer
Status: COMPLETED
Conditions: Esophageal Cancer|Gastric Cancer
Interventions: DRUG: Bryostatin-1|DRUG: Paclitaxel (Taxol)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stereotactic Body Radiotherapy Combined With Cadonilimab for Advanced Refractory Malignant Solid Tumors
Status: NOT_YET_RECRUITING
Conditions: Advanced Solid Tumor|Stereotactic Body Radiotherapy|Immune Checkpoint Inhibitor|Safety|Efficacy
Interventions: DRUG: Cadonilimab|RADIATION: Stereotactic body radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of 1 Year Vitamin D or D Plus B-vitamins on Bone Markers in Elderly People (KnoVIB)
Status: COMPLETED
Conditions: Nutritional Supplement Toxicity
Interventions: DIETARY_SUPPLEMENT: Vitamin D and Calcium|DIETARY_SUPPLEMENT: Vitamin D, Calcium, Vitamins B9, B6, B12
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Impact of Astaxanthin on Cognition in Recreationally Active Females
Status: RECRUITING
Conditions: Mental Fatigue
Interventions: DIETARY_SUPPLEMENT: Astaxanthin|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Wearable Emotion Prosthetics for Post Traumatic Stress Disorder
Status: COMPLETED
Conditions: Health Behavior
Interventions: OTHER: Tuned Vibroacoustic Stimulation (TVS)|OTHER: no active intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: COLchicine and Thiamine in Heart Failure Due to Ischemic Heart Disease
Status: RECRUITING
Conditions: Heart Failure
Interventions: DRUG: Colchicine 0.5 MG|DRUG: Colchicine placebo|DRUG: Thiamine Mononitrate 300 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Sandalwood Aromatherapy on Anxiety Levels of Pediatric
Status: NOT_YET_RECRUITING
Conditions: Anxiety, Dental
Interventions: OTHER: sandalwood aromatherapy (Santalum album)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Studying Tumor Tissue Samples From Patients With Melanoma Who Have Undergone Sentinel Lymph Node Biopsy
Status: UNKNOWN
Conditions: Melanoma (Skin)
Interventions: GENETIC: gene expression analysis|GENETIC: mutation analysis|OTHER: diagnostic laboratory biomarker analysis|OTHER: immunohistochemistry staining method|PROCEDURE: sentinel lymph node biopsy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study the Effects of Vitamin D and Calcium Supplementation at Tolerable Upper Limit Doses on Calcium Metabolism.
Status: COMPLETED
Conditions: Delusion of Reference
Interventions: DIETARY_SUPPLEMENT: Endocrine Society UL Dosage Vitamin D|DIETARY_SUPPLEMENT: Institute of Medicine Dosage Vitamin D|DIETARY_SUPPLEMENT: Calcium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effects of Kangaroo Mother Care Among Low Birth Weight (LBW) and Preterm Infants
Status: COMPLETED
Conditions: LBW|Preterm
Interventions: BEHAVIORAL: Kangaroo Mother Care|BEHAVIORAL: Standard Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Mitochondrial Oxygraphy on Subcutaneous and Peri-visceral Adipose Tissue: Influence of Body Composition
Status: TERMINATED
Conditions: Digestive Organs--Cancer|Bariatric Surgery Candidate|Parietal Region Trauma
Interventions: PROCEDURE: adipose surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Evaluating the Influence of Ready-to-use (RTU) Parenteral Nutrition in the Clinical Outcome of Patients Study
Status: COMPLETED
Conditions: Parenteral Nutrition
Interventions: DIETARY_SUPPLEMENT: RTU TPN with olive oil as the primary lipid source|OTHER: CNF Parenteral nutrition|OTHER: CNF parenteral nutrition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Healthy Cantonese Diet on Cardiometabolic Syndrome
Status: UNKNOWN
Conditions: Cardiovascular Diseases|Cardiovascular Risk Factor|High Blood Pressure|Hypertension|Hyperlipidemias|Hyperglycemia
Interventions: OTHER: the healthy Cantonese diet|OTHER: the typical Cantonese diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Trial Comparing a Multi-Modal Pain Protocol With and Without Opioids Following Total Joint Arthroplasty
Status: COMPLETED
Conditions: Total Knee Arthroplasty
Interventions: DRUG: Oxycodone|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: PREPL in Health and Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Hypotonia-Cystinuria Syndrome|Muscle Hypotonia|Healthy Volunteers|Dwarfism, Growth Hormone Deficiency|Obesity|Prader-Willi Syndrome
Interventions: PROCEDURE: Blood draw|PROCEDURE: muscle biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Intra-Corporeal Anastomosis Result in Quicker Return of Bowel Function/Earlier Discharge
Status: RECRUITING
Conditions: Colorectal Disorders
Interventions: PROCEDURE: Right Hemicolectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Registry of Avance® Nerve Graft's Utilization and Recovery Outcomes Post Peripheral Nerve Reconstruction
Status: RECRUITING
Conditions: Peripheral Nerve Injuries
Interventions: OTHER: Processed Human Nerve Graft|OTHER: Standard Treatment, Autogenous Nerve Graft, Direct Suture, etc.|OTHER: Autogenous Nerve Graft|DEVICE: Nerve Tube Conduit|PROCEDURE: Autologous Breast Reconstruction with Neurotization|PROCEDURE: Autologous Breast Reconstruction without Neurotization
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: (CBDRA60) to Prevent or Reduce Symptoms of COVID-19 and Prevention of Post-Acute Sequelae of SARS-CoV-2 Infection PASC
Status: UNKNOWN
Conditions: COVID-19|SAR
Interventions: DIETARY_SUPPLEMENT: CBDRA60 supplement|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evolution of Lung 18FDG Uptake in Patients With Idiopathic Pulmonary Fibrosis and Receiving Pirfenidone
Status: UNKNOWN
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: RADIATION: 18FDG-PET scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study to Explore the Effect of Moringa Oleifera (E-HS-01) on Flow Mediated Dilatation and Hemodynamics
Status: UNKNOWN
Conditions: Endothelial Function
Interventions: OTHER: Moringa oleifera (E-HS-01)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Promoting Preconception Care and Diabetes Self-Management Among Reproductive-Aged Women With Diabetes
Status: RECRUITING
Conditions: Diabetes Mellitus, Type 2|Electronic Health Record|Primary Health Care|Reproductive Behavior
Interventions: BEHAVIORAL: Medication Reconciliation (MedRec) Tool|BEHAVIORAL: Provider Alert and Decision Support|BEHAVIORAL: PREPSheet|BEHAVIORAL: Text Messaging
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Phase 2 Trial of AEZS-108 in Chemotherapy Refractory in Triple Negative Breast Cancer
Status: TERMINATED
Conditions: Breast Cancer
Interventions: DRUG: AEZS-108|DRUG: SCCC|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I Trial of Endocavitary Injection of Bone Marrow Derived CD133+ Cells in Ischemic Refractory Cardiomyopathy (RECARDIO Trial)
Status: COMPLETED
Conditions: Chronic Myocardial Ischemia
Interventions: OTHER: Autologous bone marrow derived-CD133+ cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Prophylactic Effect of Stilamin on Post-Endoscopic Retrograde Cholangiopancreatography Pancreatitis
Status: UNKNOWN
Conditions: Post-ERCP Acute Pancreatitis
Interventions: DRUG: Stilamin+common daily treatment|OTHER: Common daily practice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Phase II Study of Campath-1H Antibody to Treat Waldenstrom's Macroglobulinemia
Status: COMPLETED
Conditions: Lymphoplasmacytic Lymphoma|Waldenstrom's Macroglobulinemia
Interventions: DRUG: Campath-1H
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tulip Study: Testing the Usefulness of Lantus When Initiated Prematurely In Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Insulin Glargine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Parenteral Versus Combined Parenteral With Vancomycin-soaked Graft in ACL Reconstruction
Status: NOT_YET_RECRUITING
Conditions: Infection, Bacterial
Interventions: DRUG: Parenteral Antibacterial Agents|DRUG: Parenteral Antibacterial Agents plus Vancomycin pre-soaked graft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Movement for Depression - An RCT Assessing the Effects of Physical Activity Promotion for People With MDD
Status: UNKNOWN
Conditions: Major Depressive Disorder
Interventions: BEHAVIORAL: Physical activity promotion + TAU|BEHAVIORAL: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Prospective, Multicenter, Open-label 12 Week Neoadjuvant Phase II Trial Optimizing Taxane Therapy in Elderly Patients With Low Response
Status: ACTIVE_NOT_RECRUITING
Conditions: Early Primary Breast Cancer
Interventions: DRUG: Myocet|DRUG: Cyclophosphamide|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Three Techniques for Analgesia After Abdominoplasty
Status: UNKNOWN
Conditions: Abdominoplasty Patients
Interventions: DRUG: Transevrsus abdominus plane block|DRUG: Rectus sheath block|DRUG: local anesthesia infiltartion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Alemtuzumab Use (MabCampath®) in Hematopoietic Transplant of Unrelated Donor With Reduced Intensity Conditioning
Status: TERMINATED
Conditions: Graft Versus Host Disease
Interventions: DRUG: Alemtuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Buprenorphine Sublingual Spray for the Treatment of Moderate to Severe Pain
Status: TERMINATED
Conditions: Post-operative Pain
Interventions: DRUG: Buprenorphine Sublingual Spray|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Childhood and Adolescent Migraine Prevention Study
Status: TERMINATED
Conditions: Migraine|Migraine Disorders|Headache
Interventions: DRUG: Amitriptyline|DRUG: Topiramate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Secured Access to Nivolumab for Adult Patients With Selected Rare Cancer Types
Status: COMPLETED
Conditions: Carcinoma, Renal Cell|Head and Neck Neoplasm|Skin Neoplasms|Microsatellite Instability|Penile Neoplasms|Cancer With POLE Exonucleasic Domain Mutation
Interventions: DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PD-1 Inhibitor Combined With Bevacizumab and FOLFIRI Regimen in the Second-line Treatment of Advanced Colorectal Cancer
Status: UNKNOWN
Conditions: MSI-H Advanced Colorectal Cancer
Interventions: DRUG: Pembrolizumab (PD-1 Inhibitor) Combined With Bevacizumab and FOLFIRI Regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hybrid Capture 2 Human Papiloma Virus (HPV) High-Risk Anal DNA Test
Status: COMPLETED
Conditions: Anal Canal HPV Infection Diagnosis|Anal Dysplasia Diagnosis|Anal Cancer
Interventions: DEVICE: HC2 collection kit with a swab or brush
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Feeding Infant Formula With Added Probiotics and Whey Protein Concentrate
Status: COMPLETED
Conditions: Focus on Healthy Infants
Interventions: OTHER: Probiotic|OTHER: Whey protein concentrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study on the Efficacy of Glucosamine Sulfate Potassium Chloride/Standardized Ginkgo Biloba Leaf Extract in Adults With Osteoarthritis of the Knee.
Status: COMPLETED
Conditions: Osteoarthritis of the Knee
Interventions: DIETARY_SUPPLEMENT: Glucosamine Sulfate Potassium Chloride/Standardized Ginkgo Biloba Extract|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Study of ST266 Given by Intranasal Delivery in Glaucoma Suspect Subjects
Status: COMPLETED
Conditions: Ocular Hypertension
Interventions: COMBINATION_PRODUCT: ST266 via Intranasal Delivery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing the Efficacy of Epidural and Quadratus Lumborum Analgesia After Open Nephrectomy Surgery
Status: COMPLETED
Conditions: Open Nephrectomy Surgery
Interventions: PROCEDURE: Quadratus lumborum block|PROCEDURE: Epidural analgesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Tolerability and Pharmacokinetics Study of HEC110114 Tablets in Healthy Adult Subjects
Status: COMPLETED
Conditions: Chronic Hepatitis C
Interventions: DRUG: HEC110114 tablet|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Maternal Serum Homocysteine Levels and Uterine Artery Pulsatility Indices in Preterm Labor
Status: COMPLETED
Conditions: Preterm Labor
Interventions: DIAGNOSTIC_TEST: Uterine artery doppler|DIAGNOSTIC_TEST: Maternal serum homocysteine estimation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: FDDNP Protocol for Visualizing Brain Proteinopathies to Assist in the Diagnosis of Persons With Suspected CTE and AD
Status: WITHDRAWN
Conditions: Suspected Chronic Traumatic Encephalopathy (CTE) or Traumatic Encephalopathy Syndrome (TES)|Suspected Alzheimer's Disease (AD)
Interventions: BIOLOGICAL: [F-18]FDDNP-PET
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Bioequivalence Study With Pharmacokinetic Endpoints, Comparing a Single Dose of Iron Sucrose Azad Injection of Azad Pharma Corporation (AG), With a Single Dose of Venofer® Injection of Vifor Corporation (AG) in Healthy Adult Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Iron Sucrose Azad|DRUG: Venofer®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: PEACE for ImPACT Study
Status: ENROLLING_BY_INVITATION
Conditions: Autism Spectrum Disorder
Interventions: BEHAVIORAL: PEACE Online Resources|BEHAVIORAL: PEACE Weekly Group Facilitation|BEHAVIORAL: PEACE Weekly Individual Facilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treating Congestive HF With hiPSC-CMs Through Endocardial Injection
Status: UNKNOWN
Conditions: Cardiovascular Diseases|Congestive Heart Failure|Dilated Cardiomyopathy
Interventions: BIOLOGICAL: hiPSC-CM therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Repurposing Colchicine for Reduction of Residual Inflammatory Risk in Type 1 Diabetes
Status: RECRUITING
Conditions: Type 1 Diabetes|Cardiovascular Diseases|Chronic Inflammation
Interventions: DRUG: Colchicine 0.5 MG Oral Tablet|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Coenzyme Q10 Supplementation in Children With Idiopathic Dilated Cardiomyopathy
Status: COMPLETED
Conditions: Dilated Cardiomyopathy
Interventions: DRUG: Coenzyme Q10|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment to Enhance Cognition in Bipolar Disorder
Status: COMPLETED
Conditions: Bipolar Disorder|Psychosis
Interventions: BEHAVIORAL: BrainWorks|BEHAVIORAL: Computer Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cultured Autologous Oral Mucosa Epithelial Sheet for the Treatment of Bilateral Limbal Stem Cell Deficiency
Status: RECRUITING
Conditions: Total Bilateral Limbal Cell Deficiency
Interventions: BIOLOGICAL: FEMJA transplatation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT