pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Acid Reflux and Stromal Fibroblasts in Barrett's Esophagus
Status: COMPLETED
Conditions: Barrett's Esophagus|GERD
Interventions: PROCEDURE: Endoscopy and pH study
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Bexagliflozin Drug/Drug Interaction Study With Exenatide Injection
Status: COMPLETED
Conditions: Type2 Diabetes Mellitus
Interventions: DRUG: Bexagliflozin|DRUG: Exenatide Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mindfulness-based Cognitive Therapy for Chronic Depression
Status: COMPLETED
Conditions: Chronic Major Depression
Interventions: BEHAVIORAL: Mindfulness-based Cognitive Therapy|BEHAVIORAL: The Cognitive Behavioral Analysis System of Psychotherapy|BIOLOGICAL: Standard psychiatric care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Arcos Revision Stem: Evaluation of Clinical Performance
Status: COMPLETED
Conditions: Osteoarthritis|Avascular Necrosis|Rheumatoid Arthritis|Deformity|Fracture|Complications; Arthroplasty
Interventions: DEVICE: Arcos Revision Stem System
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Developing an Intervention to Improve the Non-Technical Skills of the Cardiac Surgical Teams
Status: NOT_YET_RECRUITING
Conditions: Patient Care Team|Coronary Artery Disease|Coronary Artery Bypass|Surgery|Hemorrhage Postoperative
Interventions: BEHAVIORAL: Simulation-Based Mastery Learning of the Non-technical skills
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Islet Transplantation in Type 1 Diabetes
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus
Interventions: BIOLOGICAL: Allogeneic Pancreatic Islet Cells|BIOLOGICAL: Antithymocyte Globulin|DRUG: Sirolimus|DRUG: Tacrolimus|BIOLOGICAL: Etanercept|PROCEDURE: Islet Transplantation|BIOLOGICAL: Basiliximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Development of Frailty Prevention Clinic in Geriatric Comprehensive Clinic RSCM:
Status: UNKNOWN
Conditions: Frailty|Sarcopenia|Resistance Training
Interventions: PROCEDURE: Resistance Training|PROCEDURE: Standard Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Oral Senicapoc on Allergen Challenge in Atopic Asthmatic Subjects
Status: COMPLETED
Conditions: Atopic Asthma
Interventions: DRUG: senicapoc|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study Concerning an Intelligent Activity-based Client-centred Training System in Neurorehabilitation
Status: COMPLETED
Conditions: Central Nervous System Diseases|Neurological Rehabilitation
Interventions: DEVICE: an intelligent client-centred task-oriented training|OTHER: Semi-structured interview
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Development of Pharmacogenomic Method to Predict Antidepressant Responsiveness
Status: UNKNOWN
Conditions: Depression|Antidepressant Drug Adverse Reaction
Interventions: DRUG: SSRI treated group|DRUG: non-SSRI treated group
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Early Remote Rehabilitation to Improve Health of the Elderly After Cardiac Surgery. (RECARD Trial)
Status: ENROLLING_BY_INVITATION
Conditions: Cardiac Rehabilitation
Interventions: DEVICE: Early mobile health intervention supplemented by weekly calls from a physiotherapist
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: IANB Success Rate With and Without Panoramic Help
Status: UNKNOWN
Conditions: Anesthesia|Anesthesia; Functional
Interventions: PROCEDURE: IANB by the guide of Panoramic|PROCEDURE: IANB without the guide of Panoramic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of the MyokinE100 (CL-EMS Alpha) Device in Inducing Visible Muscle Contraction in Healthy Volunteers
Status: COMPLETED
Conditions: ICU Acquired Weakness
Interventions: DEVICE: Electrical muscle stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: A Study of the Onset and Offset of Antiplatelet Effects Comparing Ticagrelor, Clopidogrel, and Placebo With Aspirin
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DRUG: Ticagrelor Tablets|DRUG: Clopidogrel (over encapsulated) capsule|DRUG: Aspirin Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Exposure-based Cognitive Behavior Therapy vs Traditional Cognitive Behavior Therapy for Fibromyalgia
Status: COMPLETED
Conditions: Fibromyalgia
Interventions: BEHAVIORAL: Internet-delivered exposure-based cognitive behavior therapy|BEHAVIORAL: Internet-delivered traditional cognitive behavior therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of Sodium Thiosulfate on Nephrotoxicity of Cisplatin Intraperitoneal Heat-perfusion Chemotherapy
Status: NOT_YET_RECRUITING
Conditions: Epithelial Ovarian Cancer|Acute Kidney Injury Due to Circulatory Failure
Interventions: DRUG: Sodium Sulfate|OTHER: Hydration|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Enhanced Recovery After Thoracic Surgery
Status: COMPLETED
Conditions: Enhanced Recovery After Thoracic Surgery Protocol|C-reactive Protein|White Blood Cell Count|Neutrophil/Lymphocyte Ratio|Plathelet/ Lymphocyte Ratio|Lymphocyte/Monocytes Ratio|Thoracic Surgery
Interventions: PROCEDURE: ERATS protocol applied|PROCEDURE: ERATS protocol not applied
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of Trastuzumab-Mcc-DM1 Administered Intravenously to Patients With HER2-Positive Metastatic Breast Cancer
Status: COMPLETED
Conditions: Metastatic Breast Cancer
Interventions: DRUG: Trastuzumab emtansine [Kadcyla]
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot RCT of Self-stigma Treatment for First Episode Psychosis
Status: RECRUITING
Conditions: First Episode Psychosis|Youth
Interventions: BEHAVIORAL: Narrative Enhancement and Cognitive Therapy- Young Adult, Combined with Coordinated Specialty Care|OTHER: Coordinated Specialty Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ultrasound-guided Precise Superficial Cervical Plexus Block
Status: UNKNOWN
Conditions: Superficial Cervical Plexus Block
Interventions: PROCEDURE: Conventional landmark technique|PROCEDURE: Precise block technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Interaction Study of Glycopyrrolate and Formoterol in Healthy Volunteers
Status: COMPLETED
Conditions: COPD
Interventions: DRUG: Glycopyrrolate + Formoterol|DRUG: Glycopyrrolate|DRUG: Formoterol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study of Cabergoline for the Treatment of Cocaine Dependence - 1
Status: COMPLETED
Conditions: Cocaine-Related Disorders|Substance-Related Disorders
Interventions: DRUG: Cabergoline|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Biphasic Insulin Aspart 30 in Subjects With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: biphasic insulin aspart
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Open-Label Long-term Safety Study of Tramadol HCl OAD (Once A Day) 300 mg in the Treatment of Pain Due to Osteoarthritis of the Knee
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: DRUG: Tramadol Once A Day
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Deuterated Phenanthrene Tetraol in Smokers Who Are at High Risk For Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer|Squamous Lung Dysplasia|Tobacco Use Disorder
Interventions: DRUG: deuterated phenanthrene tetraol|DRUG: pharmacological study|DRUG: laboratory biomarker analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Characteristic and Modulation of Gut Microbiota on the Consequences of Pregnancy
Status: COMPLETED
Conditions: Gestational Diabetes Mellitus|Medical Nutrition Therapy|Overweight/Obese|Gut Microbiota|Adverse Pregnancy Outcomes
Interventions: DIETARY_SUPPLEMENT: Prebiotic-containing dairy|DIETARY_SUPPLEMENT: Dietary intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Pregnenolone in Patients With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder
Interventions: DIETARY_SUPPLEMENT: placebo pregnenolone|DIETARY_SUPPLEMENT: pregnenolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Observational, Passive Surveillance Program to Collect Information on Women and Their Offspring Exposed to MenQuadfi® During Pregnancy, in United States (US)
Status: RECRUITING
Conditions: Meningococcal Infection
Interventions: BIOLOGICAL: Meningococcal polysaccharide (serogroups A, C, Y, and W) tetanus toxoid conjugate vaccine
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Impact of Probiotics on Well-being in Women
Status: NOT_YET_RECRUITING
Conditions: Female|Healthy Aging
Interventions: DIETARY_SUPPLEMENT: Lab4P|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Bosutinib in Japanese Adult Patients With Newly Diagnosed Chronic Phase Chronic Myelogenous Leukemia
Status: COMPLETED
Conditions: Leukemia, Chronic Myelogenous
Interventions: DRUG: Bosutinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study in Healthy People to Compare Two Different Tablets of BI 685509 and to Test How Food and Esomeprazole Influence the Amount of BI 685509 in the Blood
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Avenciguat (BI 685509) (intended commercial formulation (iCF))|DRUG: Avenciguat (BI 685509) (trial formulation 2 (TF2))|DRUG: esomeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I/II Study of Itraconazole for Blastomycosis, Histoplasmosis, and Sporotrichosis
Status: COMPLETED
Conditions: Histoplasmosis|Sporotrichosis|Blastomycosis
Interventions: DRUG: itraconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Evaluation of Safety, Tolerability & Pharmacokinetics of JYP0061 in Healthy Adults.
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: JYP0061|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of the Consumption of Burgers Prepared With Wine Grape Pomace Flour, on Components of the Metabolic Syndrome
Status: COMPLETED
Conditions: Food Selection|Metabolic Syndrome
Interventions: DIETARY_SUPPLEMENT: WGPF-burger|DIETARY_SUPPLEMENT: Control-burger
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Application of Neurally Adjusted Ventilatory Assist to Children After Congenital Cardiac Surgery
Status: UNKNOWN
Conditions: Mechanical Ventilation Complication|Congenital Heart Disease
Interventions: DEVICE: mode of neurally adjusted ventilatory assist|DEVICE: Mode of pressure support ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Remote Microphone (RM) - A Comparative Study
Status: COMPLETED
Conditions: Hearing Loss, Conductive
Interventions: DEVICE: BAHA|DEVICE: Wireless Audio Streaming Accessory|DEVICE: Digital Adaptive RM System|DEVICE: Hearing Aid
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Tissue Characterisation by Endoscopic GI-elastography
Status: COMPLETED
Conditions: Disorder of Upper Gastrointestinal Tract|Pancreatic Nodule|Secondary and Unspecified Malignant Neoplasm of Retroperitoneal Lymph Nodes|Secondary Malignant Neoplasm of Lymph Node
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Physiotherapy to Treat Urinary Incontinence in Athletes
Status: COMPLETED
Conditions: Urinary Incontinence
Interventions: OTHER: Phase 1: Qualitative interviews: Health care professionals|OTHER: Phase 2: Physiotherapy for urinary incontinence|OTHER: Phase 3: Qualitative Interviews: Participants
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Prospective, Randomized Study Evaluating The Efficacy of Chlorhexidine Gluconate Impregnated No-Rinse Cloths.
Status: TERMINATED
Conditions: Osteoarthritis|Infection
Interventions: OTHER: chlorhexidine impregnated cloths|OTHER: Standard of care bathing with antibacterial soap and water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Gleevec in Relapsed/Refractory T Cell Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: T Cell Non-Hodgkin Lymphoma
Interventions: DRUG: Imatinib mesylate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Postoperative Peripheral Neuropathy After Laparoscopic Colorectal Surgery
Status: COMPLETED
Conditions: Peripheral Neuropathy|Postoperative Complications
Interventions: DEVICE: Pink Pad ® (Xodus Medical Inc., New Kensington, PA)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study In Adult Healthy Volunteers To Asses Once Daily (QD) Dosing With The Selected Age-Appropriate Modified Release (MR) Formulations
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: tofacitinib modified release (MR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of PMSCs and Their Secretome for the Treatment of GvHD
Status: COMPLETED
Conditions: GVHD
Interventions: BIOLOGICAL: Secretome (set of substances released from the cell to its surroundings) of mesenchymal stem cells retrieved from the placenta (containing 400 microgram protein/ milliliter)|OTHER: 4 cc distilled water dissolved in albumin 20%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cognition, Age, and RaPamycin Effectiveness - DownregulatIon of thE mTor Pathway
Status: COMPLETED
Conditions: Cognitive Impairment, Mild|Alzheimer Disease
Interventions: DRUG: Rapamune
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Yttrium Y-90 Radioembolization in Treating Patients With Metastatic Liver Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Liver Carcinoma|Stage IV Liver Cancer|Stage IVA Liver Cancer|Stage IVB Liver Cancer
Interventions: PROCEDURE: Angiography|PROCEDURE: Computed Tomography|PROCEDURE: Planar Imaging|RADIATION: Radioembolization|PROCEDURE: Single Photon Emission Computed Tomography|RADIATION: Technetium Tc-99m Albumin Aggregated|OTHER: Yttrium Y 90 Resin Microspheres
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Benefits of Nutritional Ingredients for Type 2 Diabetes
Status: NOT_YET_RECRUITING
Conditions: Diabetes type2
Interventions: OTHER: Control: CHO Blend|OTHER: Experimental: CHO Blend plus AN100
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: OPTIMISation of Cardio-renal-metabolic-pulmonary Disease Guideline Adherence in High Risk Community Dwelling Individuals
Status: NOT_YET_RECRUITING
Conditions: Cardiovascular Diseases|Renal Disease|Metabolic Disease|Pulmonary Disease
Interventions: OTHER: NICE guidance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: High-dose Dexamethasone Versus Conventional Dose Prednisone for Initial Treatment of Primary Immune Thrombocytopenia (ITP)
Status: COMPLETED
Conditions: Purpura, Thrombocytopenic, Idiopathic
Interventions: DRUG: Prednisone|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Venetoclax-Navitoclax With Cladribine-based Salvage Therapy in Patients With Relapsed/Refractory Acute Myeloid Leukemia
Status: WITHDRAWN
Conditions: Relapsed Adult AML|Refractory AML
Interventions: DRUG: Navitoclax Dose Level -1|DRUG: Navitoclax Dose Level 0|DRUG: Navitoclax Dose Level 1|DRUG: Navitoclax Dose Level 2|DRUG: Venetoclax Dose Level -1|DRUG: Venetoclax Dose Levels 0 to 2|DRUG: Cladribine|DRUG: Cytarabine (Cladribine Low Dose Cytarabine Backbone)|DRUG: Cytarabine (CLAG-M Backbone)|DRUG: Mitoxantrone|DRUG: Granulocyte Colony-Stimulating Factor
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ecofisio, a Mobile Application for Assessment and Diagnosis Using Ultrasound Imaging for Undergraduate Health Science Students
Status: COMPLETED
Conditions: Sport Injury|Educational Problems
Interventions: DEVICE: ECOFISIO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Study of 25% Dextrose Injections in Shoulder Ligaments and Tendons to Promote Their Healing
Status: COMPLETED
Conditions: Rotator Cuff Tendinitis
Interventions: PROCEDURE: 25% dextrose in shoulder entheses|PROCEDURE: .1% lidocaine in shoulder entheses|PROCEDURE: .1% lidocaine subcu. above shouldr enth.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, Extended Early Bactericidal Activity and PK of Higher Doses Rifampicin in Adults With Pulmonary TB
Status: COMPLETED
Conditions: Pulmonary Tuberculosis (TB)
Interventions: DRUG: Rifampicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Effect of CryoBalloon Focal Ablation System on Human Esophageal Barrett's Epithelium
Status: COMPLETED
Conditions: Barrett's Esophagus
Interventions: DEVICE: Focal Cryoballoon Ablation System - 6 seconds|DEVICE: Focal Cryoballoon Ablation System - 8 seconds|DEVICE: CryoBalloon Focal Ablation System - 10 seconds
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficiency and Safety of a Procedural Sedation by Propofol on Terminally Ill Patients With Refractory Pain
Status: COMPLETED
Conditions: Refractory Pains
Interventions: DRUG: sedation with propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 3 Study of Tezacaftor (VX-661) in Combination With Ivacaftor (VX-770) in Subjects Aged 12 Years and Older With Cystic Fibrosis (CF), Who Have One F508del-CFTR Mutation and a Second Mutation That Has Been Demonstrated to be Clinically Responsive to Ivacaftor
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: Ivacaftor|DRUG: Tezacaftor/Ivacaftor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Prospective Assessment of Opioid Utilization Post-operatively in Sports Orthopaedic Surgeries
Status: COMPLETED
Conditions: Narcotic Use|Postoperative Pain|Narcotic Abuse|Opioid Use|Opioid Abuse, Uncomplicated|Opioids; Harmful Use|Analgesic Drug Dependence|Orthopedic Disorder
Interventions: OTHER: Questionnaire
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Local Anesthesia and Pain Perception During an Amniocentesis
Status: COMPLETED
Conditions: Pregnancy
Interventions: DRUG: Local Anesthesia|DRUG: Placebo Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: The Adjunctive Effect of Soft Tissue Augmentation Procedures of Moderate-severe Peri-implantitis
Status: RECRUITING
Conditions: Peri-Implantitis
Interventions: PROCEDURE: Subepithelial connective tissue|PROCEDURE: Volume stable Collagen Matrix|PROCEDURE: No soft tissue augmentation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Behavioral Activation and Medication Optimization For Improving Perioperative Mental Health In Older Adults Undergoing Oncologic Surgery
Status: RECRUITING
Conditions: Older Adults|Anxiety|Depression|Major Surgical Resection of a Thoracic Malignancy|Major Surgical Resection of an Abdominal Malignancy
Interventions: BEHAVIORAL: Behavioral Activation|OTHER: Medication Optimization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Using Genetic Polymorphisms to Predict the Efficacy and Toxicity - A Gastric Adenocarcinoma Study
Status: TERMINATED
Conditions: Gastric Adenocarcinoma
Interventions: DRUG: Capecitabine, Oxaliplatin, Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety and Tolerability of KRX-0502 (Ferric Citrate) in Children With Iron Deficiency Anemia Associated With Non-Dialysis Dependent Chronic Kidney Disease
Status: NOT_YET_RECRUITING
Conditions: Iron Deficiency Anemia Associated With Non-Dialysis Dependent Chronic Kidney Disease
Interventions: DRUG: ferric citrate|DRUG: standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of an Artificial Intelligence-Assisted, Image-Based Dietary Assessment Tool in the Framingham Heart Study
Status: RECRUITING
Conditions: Dietary Habits
Interventions: OTHER: Keenoa|OTHER: ASA24
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Blood Pressure and Cardiometabolic Risk (Diet-to-HTN)
Status: COMPLETED
Conditions: Arterial Hypertension|Menopause|Obesity|Cardiometabolic Syndrome|Cardiovascular Diseases
Interventions: DIETARY_SUPPLEMENT: Free diet Group (FDG)|DIETARY_SUPPLEMENT: Very low Calorie Ketogenic Diet Group (VLCKDG)|DIETARY_SUPPLEMENT: Intermittent Fasting Group (IFG)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: ADVAIR® DISKUS® Inhaler (Fluticasone Propionate/Salmeterol) Versus SEREVENT® DISKUS® Inhaler (Salmeterol) For The Treatment Of Chronic Obstructive Pulmonary Disease Exacerbations. ADVAIR® DISKUS® Inhaler and SEREVENT® DISKUS® Inhaler Are Trademarks of the GSK Group of Companies.
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Salmeterol|DRUG: Fluticasone Propionate/Salmeterol Combination Product
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: PK, PD, Safety & Immunogenicity of ADL-018 Lyo in Healthy Adult Subjects
Status: RECRUITING
Conditions: Healthy
Interventions: DRUG: Omalizumab 150mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: OVATURE (OVArian TUmor REsponse) A Phase III Study of Weekly Carboplatin With and Without Phenoxodiol in Patients With Platinum-Resistant, Recurrent Epithelial Ovarian Cancer
Status: COMPLETED
Conditions: Fallopian Tube Cancer|Peritoneal Neoplasms|Ovarian Cancer
Interventions: DRUG: phenoxodiol|DRUG: carboplatin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Vitamin A on Gene Expression, in Multiple Sclerosis Patient
Status: UNKNOWN
Conditions: Relapsing Remitting Multiple Sclerosis
Interventions: DIETARY_SUPPLEMENT: vitamin A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing Bowel Preparation Regimens for Flexible Sigmoidoscopy
Status: COMPLETED
Conditions: Cathartic Colon
Interventions: DRUG: Picosulfate sodium,|DRUG: phosphosoda rectal enema|DRUG: Pico-Salax and Sodium phosphate enema
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Liraglutide on Pulsatile Insulin Secretion in Subjects With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: liraglutide|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Post-operative Radiation With Cetuximab for Locally Advanced Cutaneous Squamous Cell Carcinoma of the Head and Neck
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: DRUG: Cetuximab|RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sodium Alendronate in Non Surgical Periodontal Therapy
Status: COMPLETED
Conditions: Periodontitis|Bone Resorption
Interventions: DRUG: Sodium alendronate|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Specific Allergen Immunotherapy in Grass Pollen Allergic Subjects by Epicutaneous Allergen Administration
Status: COMPLETED
Conditions: Allergies
Interventions: DRUG: Purified allergen dose 1 integrated in a Patch system|DRUG: Purified allergen dose 2 integrated in a Patch system|DRUG: Purified allergen dose 3 integrated in a Patch system|DRUG: Purified allergen integrated in a Patch system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Determination of the Effects of Change in Anxiety Level on Pain Perception in Patients Who Present to Emergency Department
Status: COMPLETED
Conditions: Pain, Acute|Anxiety
Interventions: DRUG: dexketoprofen trometamol|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 3 Study to Evaluate the Efficacy and Safety of Pimecrolimus 0.3% Ophthalmic Ointment
Status: RECRUITING
Conditions: Blepharitis
Interventions: DRUG: Pimecrolimus 0.3% Ophthalmic Ointment|DRUG: Placebo Ophthalmic Ointment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Interpersonal Psychotherapy for Depressed Adolescents and Parents
Status: COMPLETED
Conditions: Major Depression|Dysthymic Disorder|Adjustment Disorders|Depressive Disorder Not Otherwise Specified
Interventions: BEHAVIORAL: Interpersonal Therapy for Depressed Adolescents & Parents
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical and Immunohistochemical Effect of Topical Pimecrolimus in Treatment of Oral Lichen Planus
Status: COMPLETED
Conditions: Oral Lichen Planus
Interventions: DRUG: Pimecrolimus 1% cream|DRUG: Betamethasone 17-valerate 0.1% cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Virtual Reality Distraction During Phlebotomy in Children
Status: COMPLETED
Conditions: Pain, Acute|Child, Only|Anxiety and Fear
Interventions: DEVICE: passive virtual reality distraction|DEVICE: active virtual reality distraction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: CKD-330 Phase 3 Trial in Amlodipine Non-responder
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: CKD-330 16/5mg|DRUG: Amlodipine 5mg Placebo|DRUG: CKD-330 16/5mg Placebo|DRUG: Amlodipine 5mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Immunogenicity of EV71 Vaccine in Pediatric Subjects Aged 3 to 6 Years and 6 to 35 Months Old
Status: COMPLETED
Conditions: Enterovirus Infections
Interventions: BIOLOGICAL: EV71 vaccine ([0.5 μg total protein + adjuvant 150 μg AIPO4] per dose)|BIOLOGICAL: EV71 vaccine ([1 μg total protein + adjuvant 150 μg AIPO4] per dose)|BIOLOGICAL: EV71 vaccine ([2 μg total protein + adjuvant 150 μg AIPO4] per dose)|BIOLOGICAL: EV71 vaccine (2 μg total protein per dose)|BIOLOGICAL: EV71 vaccine ([0.5 μg total protein + adjuvant 150 μg AIPO4] per dose)|BIOLOGICAL: EV71 vaccine ([1 μg total protein + adjuvant 150 μg AIPO4] per dose)|BIOLOGICAL: EV71 vaccine (1 μg total protein per dose)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Impact of Transcranial Direct Current Stimulation on Language Functions in Mild Cognitive Impairment
Status: COMPLETED
Conditions: Mild Cognitive Impairment
Interventions: DEVICE: tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Randomized, Double-Blind, Placebo-Controlled Study With an Open-Label Period on Efficacy and Safety of Fremanezumab in Chinese Adults With Migraine
Status: COMPLETED
Conditions: Migraine
Interventions: DRUG: Fremanezumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of AGS-1C4D4 in Pancreatic Cancer Subjects Previously Treated in Protocol 2008002
Status: COMPLETED
Conditions: Pancreatic Cancer|Carcinoma, Pancreatic Ductal|Pancreatic Disease
Interventions: BIOLOGICAL: AGS-1C4D4|BIOLOGICAL: gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bortezomib, Ascorbic Acid, and Melphalan in Treating Patients With Newly Diagnosed Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma and Plasma Cell Neoplasm
Interventions: DIETARY_SUPPLEMENT: ascorbic acid|DRUG: bortezomib|DRUG: melphalan
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Combination of Teriflunomide and Danazol for Steroid-resistant/Relapse Immune Thrombocytopenia
Status: RECRUITING
Conditions: Immune Thrombocytopenia
Interventions: DRUG: Teriflunomide|DRUG: Danazol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Safety and Efficacy of UNR844 Chloride (UNR844-Cl) Eye Drops in Subjects With Presbyopia.
Status: COMPLETED
Conditions: Presbyopia
Interventions: DRUG: UNR844-Cl|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Envelope Coronally Advanced Flap and Modified Tunnel Technique in Soft Tissue Dehiscence Around Implants
Status: COMPLETED
Conditions: Dental Implants
Interventions: PROCEDURE: Mucogingival surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of DF1001 in Patients With Advanced Solid Tumors
Status: RECRUITING
Conditions: Solid Tumor, Adult
Interventions: DRUG: DF1001|DRUG: Nivolumab|DRUG: Nab paclitaxel|DRUG: Sacituzumab Govitecan-hziy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: International Registry of Acute Kidney Injury in Cirrhosis: The GLOBAL AKI Project
Status: COMPLETED
Conditions: Liver Cirrhosis|Acute Kidney Injury|Hepatorenal Syndrome
Interventions: COMBINATION_PRODUCT: Crystalloids, albumin, vasoconstrictors, diuretics, renal replacement therapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Paricalcitol Improves Anemia of Inflammation
Status: RECRUITING
Conditions: Anemia
Interventions: DRUG: Paricalcitol|DRUG: Epoetin beta|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, and Pharmacokinetics, of Single and Multiple Ascending Doses of FP-020 in Healthy Adult Volunteers
Status: RECRUITING
Conditions: Healthy
Interventions: DRUG: FP-020|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Human Leukocyte Antigen (HLA) - A*2402 Restricted Peptide Vaccine Therapy in Patients With Advanced Gastric Cancer
Status: COMPLETED
Conditions: Gastric Cancer
Interventions: BIOLOGICAL: peptide vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Cetuximab in Combination With Irinotecan and 5- FU/FA in Treatment of Metastatic Gastric Cancer
Status: COMPLETED
Conditions: Adenocarcinoma of Stomach or Esophagogastric Junction
Interventions: DRUG: Cetuximab IF
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non-invasive Evaluation of Portal Hypertension in Patients With Compensated Advanced Chronic Liver Disease by Assessment of Spleen Stiffness Using VCTE by FibroScan.
Status: COMPLETED
Conditions: Advanced Chronic Liver Disease, NASH
Interventions: DEVICE: VCTE with splenic stiffness measurement
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Contribution of UGT2B17 to the Pharmacokinetics of Diclofenac
Status: RECRUITING
Conditions: Interaction
Interventions: DRUG: Diclofenac|DIETARY_SUPPLEMENT: curcumin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Indocyanine Green for Detection of Sentinel Lymph Nodes In Comparison to ICG Plus Technetium in the Evaluation of Vulvar Squamous Cell Carcinoma
Status: NOT_YET_RECRUITING
Conditions: Vulvar Cancer
Interventions: PROCEDURE: ICG alone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Single-Center Exploratory Study to Assess the Activity of CRx-197-002 in Plaque Psoriasis
Status: COMPLETED
Conditions: Plaque Psoriasis
Interventions: DRUG: CRx-197|DRUG: CRx-197|DRUG: Nortriptyline|DRUG: Calcipotriol|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Corneal Thickness Changes During Corneal Collagen Cross-linking With Ultraviolet-A Irradiation and Riboflavin
Status: COMPLETED
Conditions: Progressive Keratoconus|Thin Corneas
Interventions: DRUG: cross-linking with hypo-osmolar riboflavin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ULTRA-HFIB-Redo: Ultrasound-based Renal Sympathetic Denervation vs Control in Redo Ablation Patients
Status: RECRUITING
Conditions: Paroxysmal Atrial Fibrillation|Persistent Atrial Fibrillation
Interventions: DEVICE: Renal Denervation|DEVICE: Catheter Ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Endurant™ Stent Graft System in the Treatment of Infra-renal Abdominal Aortic Aneurysms (ENDURANT France)
Status: COMPLETED
Conditions: Aneurysm|Aortic Aneurysm|Aortic Aneurysm, Abdominal|Vascular Diseases|Cardiovascular Diseases|Aortic Diseases
Interventions: DEVICE: Endurant Stent graft
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Dose Esmolol Infusion Have an Adjuvant Effect to TAP Block for Pain Control in Laparoscopic Cholecystectomy.
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: Esmolol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Chewing Gum on a Computer Task and Liking Ratings of Ice Cream
Status: ACTIVE_NOT_RECRUITING
Conditions: Habituation
Interventions: OTHER: NO GUM|OTHER: MCC (Mint Chocolate Chip gum)|OTHER: C (Cinnamon gum)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: PReventive Effect Of Left Bundle Branch Area Pacing Versus righT vEntricular paCing on All Cause deaTh, Heart Failure Progression, and Ventricular dysSYNChrony in Patients With Substantial Ventricular Pacing (PROTECT-SYNC): Multicenter Prospective Randomized Controlled Trial
Status: RECRUITING
Conditions: Bradyarrhythmia|Atrioventricular Block|Left Bundle Branch Area Pacing
Interventions: PROCEDURE: Left bundle branch area pacing|PROCEDURE: Right ventricular pacing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Preoperative Intravenous Ferric Carboxymaltose and Placebo in the Treatment of Patients Undergoing Cardiac Surgery
Status: UNKNOWN
Conditions: Coronary Artery Disease|Postoperative Complications|Aortic Valve Stenosis|Mitral Valve Disease|Aortic Aneurysm, Thoracic
Interventions: DRUG: Ferric carboxymaltose|OTHER: Physiological saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: CD34+ Cell Enriched and T Cell Depleted Allogeneic Stem Cell Transplantation for Patients With Mismatched Related Donors or Borderline Organ Function
Status: COMPLETED
Conditions: Malignant Diseases|Non-malignant Diseases
Interventions: DEVICE: CliniMACS CD34+ cell enrichment and T-cell depletion
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EGESTA - Emergent GI Therapy for Severe, Complicated CDI Using Fecal Microbiota Transplant
Status: WITHDRAWN
Conditions: C.Difficile Colitis
Interventions: BIOLOGICAL: fecal microbiota transplant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Amrubicin (AMR) Trial in Patients With Non-small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DRUG: Amrubicin hydrocloride|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Ledipasvir/Sofosbuvir (LDV/SOF) Fixed-Dose Combination (FDC) for 6 Weeks in Adults With Acute Genotype 1 or 4 Hepatitis C Virus (HCV) and Chronic Human Immunodeficiency Virus (HIV)-1 Co-Infection
Status: COMPLETED
Conditions: Hepatitis C Infection With HIV Co-Infection
Interventions: DRUG: LDV/SOF
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multi-Dimensional MRI Spatial Heterogeneity Analysis for Predicting Key Genes and Prognosis of High-Grade Gliomas: A Multi-Center Study
Status: NOT_YET_RECRUITING
Conditions: High-grade Glioma
Interventions: DIAGNOSTIC_TEST: MR scanning; Clinical data collection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Astaxanthin Formulation Bioavailability
Status: COMPLETED
Conditions: Bioavailability of Astaxanthin Formulations
Interventions: DIETARY_SUPPLEMENT: Enteric Coated Softgels|DIETARY_SUPPLEMENT: Liposomal astaxanthin|DIETARY_SUPPLEMENT: Standard Softgel|DIETARY_SUPPLEMENT: Astaxanthin Water Soluble Emulsion|DIETARY_SUPPLEMENT: Astaxanthin Water Dispersible Powder|DIETARY_SUPPLEMENT: Standard Softgel with Astaxanthin Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: CST1-Guided Oral Glucocorticoids Management for CRSwNP
Status: NOT_YET_RECRUITING
Conditions: Chronic Rhinosinusitis With Nasal Polyps|Glucocorticoids
Interventions: DRUG: Oral Glucocorticoids|DRUG: Oral placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Radiation Therapy Followed By Combination Chemotherapy in Treating Young Patients With Supratentorial Primitive Neuroectodermal Tumors
Status: UNKNOWN
Conditions: Brain and Central Nervous System Tumors
Interventions: DRUG: cisplatin|DRUG: lomustine|DRUG: vincristine sulfate|PROCEDURE: adjuvant therapy|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Does Ultraviolet Irradiation Reduce Platelet Reactivity and Improve Coronary Microvascular Function in Man?
Status: COMPLETED
Conditions: Hypertension
Interventions: RADIATION: UVA Radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Raloxifene With or Without Exercise Compared With Exercise Alone in Women Who Have Been Previously Treated for Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer|Menopausal Symptoms|Osteoporosis
Interventions: DRUG: raloxifene|PROCEDURE: quality-of-life assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: SUPPORTIVE_CARE
Clinical trial: TNF-alpha Inhibition in CRPS: A Randomized Controlled Trial
Status: WITHDRAWN
Conditions: CRPS|Chronic Regional Pain Syndrome
Interventions: DRUG: Etanercept|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Intraperitoneal Application of Levobupivacaine During Laparoscopic Surgery in Kids.
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Levobupivacaine 0.5%|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: