pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Late Phase 2 Study of OPC-12759 Ophthalmic Suspension
Status: COMPLETED
Conditions: Dry Eye Syndromes
Interventions: DRUG: placebo|DRUG: 1% OPC-12759 ophthalmic suspension|DRUG: 2% OPC-12759 ophthalmic suspension
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Acupuncture for Postoperative Urinary Retention After Hemorrhoidectomy: a Randomized Controlled Trial
Status: COMPLETED
Conditions: Postoperative Complications|Postoperative Urinary Retention
Interventions: OTHER: Acupuncture|OTHER: Sham acupuncture|DRUG: Neostigmine Injectable Product
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Two HMOs in Chinese Infants
Status: NOT_YET_RECRUITING
Conditions: Healthy Infants
Interventions: OTHER: Experimental Group (EG)|OTHER: Control Group (CG)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: The Crohn's Disease Exclusion Diet With Early Dairy Introduction Plus Partial Enteral Nutrition for Crohn's Disease
Status: RECRUITING
Conditions: Crohn Disease
Interventions: DIETARY_SUPPLEMENT: CDED+PEN|DIETARY_SUPPLEMENT: PEN+usual care|DIETARY_SUPPLEMENT: CDED+dairy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study Evaluating MAC-321 in Non-small Cell Lung Cancer Refractory to Platinum-based Therapy
Status: COMPLETED
Conditions: Carcinoma, Non-Small-Cell Lung|Lung Neoplasms
Interventions: DRUG: MAC-321
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Long-Term Extension Study of RoActemra/Actemra (Tocilizumab) in Patients With Juvenile Idiopathic Arthritis From France Who Completed WA19977 Core Study
Status: COMPLETED
Conditions: Juvenile Idiopathic Arthritis
Interventions: DRUG: tocilizumab [RoActemra/Actemra]
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Novel Strategies to Improve Immunomodulation and Non-invasive Clinical Monitoring in VCA
Status: TERMINATED
Conditions: Amputation, Traumatic|Amputation;Traumatic;Old|Face Injury|Face; Deformity|Abdominal Wall Defect
Interventions: DRUG: IL-2
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Correlation Between Circulating Resistin and Vascular Inflammation Measured by 18F-fluorodeoxyglucose (FDG) Positron Emission Tomography (PET) (18FDG-PET)
Status: COMPLETED
Conditions: Atherosclerosis
Interventions: OTHER: Cross sectional study
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of a Modified Paleolithic Dietary Intervention in the Treatment of Relapsing-Remitting Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis, Relapsing-remitting
Interventions: OTHER: Modified Paleo diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neurocognition in NSCLC Patients Treated With Osimertinib or Osimertinib + WBI
Status: RECRUITING
Conditions: Neurocognitive
Interventions: RADIATION: Osimertinib and whole-brain irradiation|DRUG: Osimertinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Evaluate the Efficacy of Eleutherococcus Senticosus for Subjects Under Renal Dialysis
Status: COMPLETED
Conditions: Renal Dialysis
Interventions: DIETARY_SUPPLEMENT: Eleutherococcus senticosus|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of LY3502970 in Participants With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: LY3502970|DRUG: Dulaglutide|DRUG: Placebo|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Exercise Videogames for Physical Activity Adoption and Maintenance
Status: COMPLETED
Conditions: Physical Activity
Interventions: BEHAVIORAL: Exercise Video Games|BEHAVIORAL: Aerobic Exercise|BEHAVIORAL: Home exercise videogames|BEHAVIORAL: Home Standard Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Gemcitabine, Carboplatin and VELIPARIB (ABT-888) in Refractory Testicular Germ Cell Cancer
Status: COMPLETED
Conditions: Testicular Cancer
Interventions: DRUG: Veliparib|DRUG: Gemcitabine|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mini-hysteroscopy Versus Conventional Office Hysteroscopy in Nulliparous Patients Undergoing Office Hysteroscopy
Status: UNKNOWN
Conditions: Pain
Interventions: DEVICE: Mini-hysteroscopy|DEVICE: Conventional Office Hysteroscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Comparison of the Effects of Weight Changes on Serum Adipokines in Patients Diagnosed With Anorexia Nervosa and Morbid Obesity
Status: COMPLETED
Conditions: Anorexia Nervosa|Bariatric Surgery|Weight Change, Body
Interventions: PROCEDURE: Bariatric surgery-RYGB|BEHAVIORAL: Dietary intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single Arm Trial of Preoperative Stereotactic Body Radiation Therapy (SBRT) for T3a or Gleason Grade Group 4 Prostate Cancer
Status: WITHDRAWN
Conditions: Prostate Cancer
Interventions: DEVICE: Stereotactic Body Radiation Therapy (SBRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Percutaneous Coronary Intervention Before Transcatheter Aortic Valve Implantation
Status: RECRUITING
Conditions: Valvular Heart Disease|Aortic Valve Stenosis|Coronary Artery Disease
Interventions: PROCEDURE: No PCI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Ad-RTS-hIL-12 + Veledimex in Combination With Cemiplimab in Subjects With Recurrent or Progressive Glioblastoma
Status: COMPLETED
Conditions: Glioblastoma
Interventions: BIOLOGICAL: Ad-RTS-hIL-12|DRUG: Veledimex|DRUG: Cemiplimab-Rwlc
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Brigatinib to Treat Adults With Anaplastic Lymphoma Kinase (ALK) Positive Metastatic Non Small Cell Lung Cancer (NSCLC)
Status: COMPLETED
Conditions: Carcinoma, Non-Small-Cell Lung|Anaplastic Lymphoma Kinase
Interventions: OTHER: No Intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Left Septal or Deep Septal Pacing to Prevent Pacing-induced Cardiomyopathy
Status: RECRUITING
Conditions: Complete Heart Block|Second Degree Atrioventricular Block Möbitz Type II
Interventions: DEVICE: Pacemaker implant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Liquid Biopsy System Intracoronary Blood Sampling and Analysis to Characterise Disease Biomarkers in Patients With Coronary Disease
Status: RECRUITING
Conditions: Coronary Artery Disease
Interventions: DEVICE: Liquid Biopsy System (LBS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Fecal Microbial Transplantation for Ileal Pouch Anal Anastomosis Patients
Status: RECRUITING
Conditions: Ileal Pouch Anal Anastomosis
Interventions: BIOLOGICAL: Fecal Microbial Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity Following Meningococcal and Pneumococcal Immunization Among Adult People Living With HIV
Status: RECRUITING
Conditions: Hiv|Meningococcal Infections|Pneumococcal Infections
Interventions: DRUG: Neisseria meningitidis oligosaccharide conjugate vaccine and recombinant protein-based vaccine|DRUG: 13 valent pneumococcal conjugate vaccine and 23 valent pneumococcal polysaccharide vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety and Immunogenicity of Adjuvanted Reduced Dose Inactivated Polio Vaccine Given at 6, 10, 14 Weeks and 9 Months
Status: COMPLETED
Conditions: Poliomyelitis
Interventions: BIOLOGICAL: IPV-Al SSI|BIOLOGICAL: IPV SSI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Maximizing the Benefit of Renin-Angiotensin Blocking Drugs in Diabetic Renal Disease.
Status: COMPLETED
Conditions: Diabetic Nephropathy
Interventions: DRUG: Addition of furosemide 20 mg oral bid to baseline regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Basiliximab vs Low-dose Thymoglobulin Induction Therapy in Low Risk Kidney Transplant Patients
Status: COMPLETED
Conditions: Kidney Transplant Rejection|Kidney Transplant; Complications
Interventions: DRUG: Basiliximab|DRUG: Thymoglobulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bevacizumab, Pemetrexed Disodium, and Cisplatin or Erlotinib Hydrochloride and Bevacizumab in Treating Patients With Stage IV Non-Small Cell Lung Cancer. A Multicenter Phase II Trial Including Biopsy at Progression (BIO-PRO Trial).
Status: COMPLETED
Conditions: Lung Cancer
Interventions: BIOLOGICAL: bevacizumab, erlotinib|DRUG: bevacizumab, pemetrexed, cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Update and Biodistribution of [F-18]FMDHT pET/CT in Normal Healthy Volunteers and Patients With Metastatic Prostate Cancer - A First in Human Subject Study With [F-18] FMDHT
Status: TERMINATED
Conditions: Prostate Cancer
Interventions: DRUG: [F-18] fluorinated dihydrotestosterone (FDHT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Benefit of Scarf Support on Skin-to-skin Time and Portage in Neonatology and at Home
Status: COMPLETED
Conditions: Infant, Newborn, Disease
Interventions: OTHER: portage scarf|OTHER: usual practice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phase II Study Assessing Safety and Efficacy of APL-2 in Glomerulopathies
Status: COMPLETED
Conditions: IgA Nephropathy|Lupus Nephritis|Membranous Nephropathy|C3 Glomerulonephritis|Dense Deposit Disease
Interventions: DRUG: APL-2
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Extension Study of ABBV-8E12 in Patients With Progressive Supranuclear Palsy (PSP) Who Completed Study C2N-8E12-WW-104
Status: COMPLETED
Conditions: Progressive Supranuclear Palsy (PSP)
Interventions: DRUG: ABBV-8E12
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acupuncture for Hot Flashes in Patients With Hormone Receptor-positive Breast Cancer.
Status: NOT_YET_RECRUITING
Conditions: Hot Flashes|Breast Cancer|Acupuncture
Interventions: OTHER: Acupuncture treatment|OTHER: Sham Acupuncture treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study in Healthy Volunteers to Investigate the Effects of Diltiazem on the Pharmacokinetics of Naloxegol
Status: COMPLETED
Conditions: Drug Induced Constipation
Interventions: DRUG: Naloxegol|DRUG: Diltiazem XR
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: To Assess Safety, Tolerability and Pharmacokinetics of BI 416970 in Healthy Male Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Placebo to BI 416970|DRUG: BI 416970
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Uptake and Biodistribution of 18F-fluorocholine in Histiocytic Disorders by PET Imaging and Biopsy Measurement
Status: COMPLETED
Conditions: Erdheim-Chester Disease|Langerhans Cell Histiocytosis|Histiocytic Disorders
Interventions: RADIATION: F-choline PET Scan|DEVICE: FDG-PET|PROCEDURE: biopsy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: TAAI Erasmus Research Initiative to Fight CF: Monitoring Inflammation in CF Lung Disease Into a New Era
Status: ACTIVE_NOT_RECRUITING
Conditions: Cystic Fibrosis|Lung Inflammation|Lung Infection|Lung Disease; Cystic|Lung Diseases|Lung Disease; Cystic, Congenital|Inflammation Lungs|Congenital Disorders|Exacerbation, Symptom|Infections, Bacterial
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Doxycycline in Levodopa Treated Parkinson's Disease Patients
Status: UNKNOWN
Conditions: Parkinson Disease
Interventions: DRUG: Doxycycline|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Filling Bone Defects/Voids With Autologous BonoFill-II for Maxillofacial Bone Regeneration
Status: UNKNOWN
Conditions: Bone Augmentation|Bone Grafts
Interventions: BIOLOGICAL: BonoFill-II
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MR-Linac Guided Adaptive FSRT for Brain Metastases From Non-small Cell Lung Cancer
Status: RECRUITING
Conditions: Non-small Cell Lung Cancer
Interventions: COMBINATION_PRODUCT: Unity-based MR-Linac guided FSRT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MP Diagnostics HTLV Blot 2.4 Post-Market Clinical Study
Status: COMPLETED
Conditions: HTLV-I Infections|HTLV-II Infections|Human T-lymphotropic Virus 1|Human T-lymphotropic Virus 2|HTLV I Associated T Cell Leukemia Lymphoma|HTLV I Associated Myelopathies
Interventions: DIAGNOSTIC_TEST: MP Diagnostics HTLV Blot 2.4
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Treatment of Notalgia Paresthetica With Xeomin
Status: COMPLETED
Conditions: Notalgia Paresthetica
Interventions: DRUG: Xeomin|DRUG: Placebo / Xeomin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Plan to Evaluate Early Endothelialization of a Polymer Free Sirolimus-eluting Coronary Stent System (VIVO ISARTM) Compared With Everolimus-eluting Durable Polymer Stent (XIENCE SkypointTM) in Patients Undergoing Percutaneous Coronary Intervention.
Status: RECRUITING
Conditions: Coronary Artery Disease
Interventions: DEVICE: VIVO ISAR DES implanted in the First lesion, XIENCE Skypoint DES implanted in the Second lesion|DEVICE: XIENCE Skypoint DES implanted in the First lesion, VIVO ISAR DES implanted in the Second lesion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Evaluate the Efficacy and Safety of Dermalax(Deep) in Correction of Nasolabial Folds
Status: COMPLETED
Conditions: Correction of Nasolabial Folds
Interventions: DEVICE: Dermalax(Deep)|DEVICE: Restylane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial to Assess the Impact of Ascorbic Acid on Cardiac Surgeries Outcomes and Complications''
Status: UNKNOWN
Conditions: Cardiothoracic Surgery
Interventions: DRUG: Ascorbic Acid 500Mg Chew Tab|OTHER: Carbonated orange beverage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Use of the Propeller Health Platform to Improve Inhaled Corticosteroid (ICS) Use Among Adults With Uncontrolled Persistent Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: BEHAVIORAL: Electronic Medication Monitors on ICS and SABA - Active Mode|BEHAVIORAL: Electronic Medication Monitors on ICS and SABA - Silent Mode|BEHAVIORAL: Asthma App Tracking of ICS/SABA Usage - Active Mode|BEHAVIORAL: Asthma App Tracking of ICS/SABA Usage - Silent Mode|BEHAVIORAL: NorthShore Connect Real Time ICS and SABA Usage Feedback - Yes|BEHAVIORAL: NorthShore Connect Real Time ICS and SABA Usage Feedback - No|BEHAVIORAL: Asthma Nurse Monthly Phone Calls for ICS/SABA Usage Feedback - Yes|BEHAVIORAL: Asthma Nurse Monthly Phone Calls for ICS/SABA Usage Feedback - No
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Role of Probiotics in Periodontal Disease
Status: COMPLETED
Conditions: Periodontal Diseases
Interventions: DIETARY_SUPPLEMENT: Probiotics|DIETARY_SUPPLEMENT: AOÇ Kefir|OTHER: Food without additional food supplements
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Prosocial Behavior and Exercise Among Older Adults
Status: UNKNOWN
Conditions: Health-Related Quality of Life|Physical Activity|Physical Function
Interventions: BEHAVIORAL: Prosocial Behavior Physical Activity (PBPA)|BEHAVIORAL: Physical Exercise (PE)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Does Pioglitazone Increase the Production of 15-EPI-Lipoxin A4?
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Pioglitazone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Natural History Study of Patients With G2019S LRRK2 Parkinson's Disease
Status: TERMINATED
Conditions: Patients With Parkinson's Disease (PD) Caused by the p.Gly2019Ser (G2019S) Pathogenic Mutation of the Leucine-Rich Repeat Kinase 2 (LRRK2) Gene
Interventions: OTHER: Observational
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study to Evaluate the Safety and Pharmacokinetics of CKD-379
Status: ACTIVE_NOT_RECRUITING
Conditions: Type II Diabetes Mellitus
Interventions: DRUG: CKD-379|DRUG: D759+D745+D029+D150
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Prospective, Single Center Clinical Study of Toripalimab Combined With FLOT Regimen for Perioperative Treatment of PD-L1 Positive Locally Advanced Resectable Gastric Cancer or Gastroesophageal Junction Adenocarcinoma (GEJ)
Status: RECRUITING
Conditions: PD-L1 Positive Locally Advanced Patients With Resectable Gastric Cancer
Interventions: DRUG: Drug: Toripalimab, FLOT(Docetaxel+oxaliplatin+leucovorin+5-FU)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reduced Nicotine Content Cigarettes in Smokers of Lower Socioeconomic Status
Status: COMPLETED
Conditions: Tobacco Dependence
Interventions: DRUG: Reduced Nicotine Content Cigarettes|DRUG: Same Nicotine Content Cigarettes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Evaluation of an Oral Contraceptive Containing 30 mg Ethinyloestradiol and 150 mg Desogestrel on Women's Health
Status: UNKNOWN
Conditions: Women With PMS
Interventions: DRUG: Marvelon
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Use of Bevacizumab as a Modulator of Wound Healing Following Trabeculectomy Surgery
Status: COMPLETED
Conditions: Glaucoma
Interventions: DRUG: bevacizumab|DRUG: 5-fluorouracil|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: S0020 Immunosuppressive Therapy in Treating Patients With Myelodysplastic Syndrome
Status: COMPLETED
Conditions: Leukemia|Myelodysplastic Syndromes
Interventions: BIOLOGICAL: anti-thymocyte globulin|DRUG: cyclosporine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Of Loop-Tip Wire Vs Tradictional Technique In The Cannulation Of The Common Bile Duct
Status: UNKNOWN
Conditions: Post-ERCP Pancreatitis
Interventions: DEVICE: Loop-tip wire (Cook Medical) for the cannulation of the CBD|DEVICE: Cannulotome CT-25mm Cook Medical
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: N2004-04: Fenretinide LXS in Treating Patients With Recurrent, Refractory, or Persistent Neuroblastoma
Status: COMPLETED
Conditions: Neuroblastoma
Interventions: DRUG: fenretinide lipid matrix|DRUG: ketoconazole|OTHER: laboratory biomarker analysis|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Tolerability, and Safety of DFN-15
Status: COMPLETED
Conditions: Migraine Headache
Interventions: DRUG: DFN-15 Active|OTHER: DFN-15 Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Self-help Books for Social Anxiety
Status: COMPLETED
Conditions: Social Anxiety
Interventions: BEHAVIORAL: Mindfulness and Acceptance Workbook for Social Anxiety and Shyness|BEHAVIORAL: The Shyness and Social Anxiety Workbook
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Study of Efficacy and Safety of a 60-day Use of the Magnox Comfort Compared to the Placebo in Subjects With NLC
Status: COMPLETED
Conditions: Nocturnal Leg Cramps
Interventions: DIETARY_SUPPLEMENT: Magnox Comfort|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of QRH-882260 Heptapeptide Application in the Colon
Status: TERMINATED
Conditions: Colon Cancer Prevention
Interventions: DRUG: QRH-882260 Heptapeptide|DEVICE: Scanning Fiber Endoscope
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Learn About the Medicine Called Nirmatrelvir Used in Combination With Ritonavir in People With Weakened Immune Systems or at Increased Risk for Poor Outcomes Who Are Hospitalized Due to Severe COVID-19
Status: WITHDRAWN
Conditions: Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)|Coronavirus Disease 2019 (COVID-19)|Immunocompromised|Hospitalization|Child, Hospitalized
Interventions: DRUG: Nirmatrelvir|DRUG: Ritonavir|DRUG: Placebo for nirmatrelvir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Geriatric Assessment and Intervention for Older Patients With Frailty in the Emergency Department
Status: COMPLETED
Conditions: Frail Elderly Syndrome|Patient Admission|Hospital Readmission|Length of Stay|Fall|Quality of Life
Interventions: OTHER: CGA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Cognitive and Mood Effects of Docosahexaenoic Acid (DHA)-Rich and Eicosapentaenoic Acid (EPA)-Rich Fish Oil in Healthy Young Adults
Status: COMPLETED
Conditions: Cognitive Function|Mood
Interventions: DIETARY_SUPPLEMENT: n-3 PUFAs|DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: n-3 PUFAs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: VivAer: A Correlation Between Symptom Scores and Objective Findings
Status: RECRUITING
Conditions: Nasal Obstruction|Medically Unexplained Symptoms|Airway Obstruction|Airway Remodeling
Interventions: DEVICE: VivAer Stylus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sitagliptin Umbilical Cord Blood Transplant Study
Status: COMPLETED
Conditions: Leukemia, Myeloid, Acute|Acute Lymphoblastic Leukemia|Myelodysplasia|Leukemia, Myelogenous, Chronic|Lymphoma, Non-Hodgkin
Interventions: DRUG: Sitagliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect and Safety of the Seasonal Trivalent Influenza Vaccine in Chronic Kidney Disease Patients Not on Dialysis
Status: UNKNOWN
Conditions: Immunogenicity and Adverse Drug Effect of Vaccines Influenza|Chronic Kidney Disease
Interventions: BIOLOGICAL: Seasonal influenza vaccine (AdimFlu-S)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Evaluate the Efficacy of ZOMETA® in Treatment of Bone Metastases in Patients With Stage IV Nasopharyngeal Cancer
Status: COMPLETED
Conditions: Nasopharyngeal Cancer
Interventions: DRUG: Zometa (zoledronic acid)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Biomarkers in Patients With Respiratory Tract Dysplasia or Lung Cancer, Head and Neck Cancer, or Aerodigestive Tract Cancer and in Normal Volunteers
Status: RECRUITING
Conditions: Esophageal Cancer|Head and Neck Cancer|Lung Cancer|Precancerous Condition
Interventions: OTHER: immunohistochemistry staining method|OTHER: laboratory biomarker analysis|OTHER: sputum cytology|PROCEDURE: biopsy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase 1 Study of ADA-011 for Subjects With Advanced Solid Tumors
Status: RECRUITING
Conditions: Solid Tumor, Adult
Interventions: DRUG: ADA-011|DRUG: PD(L)-1 inhibitor
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Motivational Interviewing to Increase PrEP Uptake (MI-PrEP)
Status: COMPLETED
Conditions: Risk Factor
Interventions: BEHAVIORAL: Experimental Intervention (MI-PrEP)|BEHAVIORAL: Enhanced Treatment as Usual (E-TAU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ARC Therapy to Restore Hemodynamic Stability and Trunk Control in People With Spinal Cord Injury
Status: RECRUITING
Conditions: Spinal Cord Injury|Orthostatic Hypotension
Interventions: DEVICE: ARC-IM Thoracic System implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CBD-Microglia PET Study
Status: RECRUITING
Conditions: CBD|Healthy
Interventions: RADIATION: [11C]PBR28|DRUG: Low-dose lipopolysaccharide|DRUG: Intradermal Capsaicin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Combination Nab-paclitaxel (N-P) and Nintedanib or N-P and Placebo in Relapsed NSCLC Adenocarcinoma
Status: WITHDRAWN
Conditions: NSCLC, Recurrent|Adenocarcinoma of Lung
Interventions: DRUG: Vargatef|DRUG: Abraxane|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics, Efficacy and Safety Study of IMMUNATE SD (Human Plasma-Derived Coagulation Factor VIII Concentrate) in Hemophilia A Patients
Status: COMPLETED
Conditions: Hemophilia A
Interventions: DRUG: Human Plasma-Derived Coagulation Factor VIII Concentrate (Virus Inactivated by Polysorbate 80 Treatment and Vapor Heat Treatment)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of PARG Inhibitor ETX-19477 in Patients With Advanced Solid Malignancies
Status: RECRUITING
Conditions: Advanced or Metastatic Solid Tumors|Breast Cancer|Ovarian Cancer|Prostate Cancer|Epithelial Ovarian Cancer|BRCA2 Mutation|ER+ Breast Cancer|Castrate Resistant Prostate Cancer|BRCA1 Mutation|BRCA Mutation|Endometrial Cancer|Colorectal Cancer|Gastric Cancer
Interventions: DRUG: ETX-19477
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Head and Neck Phase III Iressa Versus Methotrexate Refractory: Iressa Versus Methotrexate (IMEX)
Status: COMPLETED
Conditions: Squamous Cell Carcinoma of the Head and Neck
Interventions: DRUG: Gefitinib|DRUG: methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combined Effect of Dexamethasone and Paracetamol for Postoperative Sore Throat
Status: UNKNOWN
Conditions: Pharyngitis
Interventions: DRUG: Dexamethasone|DRUG: Paracetamol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Phase II Dose Finding Study of RDEA3170 Versus Placebo in Japanese Patients With Gout or Asymptomatic Hyperuricemia
Status: COMPLETED
Conditions: Gout and Hyperuricemia
Interventions: DRUG: RDEA3170|DRUG: Allopurinol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prevention of Alcohol Related Incidents in the US Air Force
Status: COMPLETED
Conditions: Alcohol Abuse
Interventions: BEHAVIORAL: Group Brief Alcohol Intervention|BEHAVIORAL: Group Brief Alcohol Intervention Booster|BEHAVIORAL: Bystander Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Efficacy of a Dentifrice in Providing Relief From Immediate and Short Term Relief From Dentinal Hypersensitivity
Status: COMPLETED
Conditions: Dentine Hypersensitivity
Interventions: DRUG: Stannous Fluoride|DRUG: Sodium Monofluorophosphate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Short-Term Effects of Dynamic Taping in Patients With Lumbar Disc Herniation
Status: NOT_YET_RECRUITING
Conditions: Lumbar Disc Herniation|Acute Pain
Interventions: OTHER: Dynamic taping technique|OTHER: Sham taping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study to Test a Medicine (Fitusiran) Injected Under the Skin for Preventing Bleeding Episodes in Male Adolescent or Adult Participants With Severe Hemophilia
Status: RECRUITING
Conditions: Hemophilia
Interventions: DRUG: Fitusiran|DRUG: Clotting factor concentrates (CFC) or bypassing agents (BPA)|DRUG: Antithrombin concentrate (ATIIIC)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pregnancy in Women With Rare Multisystemic Vascular Diseases: COGRare5 Study
Status: RECRUITING
Conditions: Vascular Anomaly|Osler Rendu Disease|Marfan Syndrome or Related|Lymphedema Primary|Arteriovenous Malformations|Cerebrospinal; Disorder
Interventions: OTHER: Questionnaire
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Tolerability Study of Multiple Doses of PF-06305591
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: PF-06305591|DRUG: Placebo|DRUG: PF-06305591|DRUG: Placebo|DRUG: PF-06305591|DRUG: Placebo|DRUG: PF-06305591|DRUG: PF-06305591
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Allopurinol Versus Febuxostat in Subjects Completing the Phase 3 Trials C02-009 or C02-010
Status: COMPLETED
Conditions: Gout
Interventions: DRUG: Febuxostat|DRUG: Febuxostat|DRUG: Allopurinol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Omnibond vs Dermabond
Status: SUSPENDED
Conditions: Osteoarthritis
Interventions: DEVICE: Omnibond Topical Skin Adhesive|DEVICE: Dermabond Advanced Topical Skin Adhesive
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Plethysmography Curve Variability Depending on the Breath Cycle
Status: UNKNOWN
Conditions: Apnea|Circulatory; Change|Respiration
Interventions: OTHER: Respiratory rate|OTHER: Tidal volume|OTHER: Apnea
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Intracoronary Provocative Test With Acetylcholine in Patients With INOCA and MINOCA
Status: RECRUITING
Conditions: Myocardial Infarction With Non-Obstructive Coronary Artery|Ischemia With Non-Obstructive Coronary Artery
Interventions: OTHER: Data collection|OTHER: Clinical follow-up
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of EGD Probe Insertion on the Intracuff Pressure of the Laryngeal Mask Airway or Cuffed Endotracheal Tube in Children
Status: COMPLETED
Conditions: Esophagogastroduodensocopy (EGD) Procedure
Interventions: DEVICE: Cuffed ETT|DEVICE: Cuffed LMA
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Varenicline for Cognitive Deficits and Cigarette Smoking in Schizophrenia - Efficacy and Predictors
Status: COMPLETED
Conditions: Schizophrenia|Cigarette Smoking
Interventions: DRUG: Varenicline|DRUG: Placebo for varenicline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Fractional Microneedling RF vs Intralesional Steroid With & Without Microneedling in Hypertrophic Scars
Status: UNKNOWN
Conditions: Hypertrophic Scars
Interventions: DEVICE: Fractional Microneedling Radiofrequency|PROCEDURE: Intralesional Steroid Injection with and without Microneedling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Active Drug Comparative, Multi-center, phase3 Clinical Study to Evaluate the Efficacy and Safety of PG201 in Osteoarthritis Patients
Status: COMPLETED
Conditions: Osteoarthritis of the Knee
Interventions: DRUG: PG201 tablet|DRUG: Celebrex capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Psoriasis、Indigo Naturalis、Chinese Medicine Medicated Bath
Status: UNKNOWN
Conditions: Psoriasis
Interventions: DRUG: paper mulberry leaf|DRUG: Triamcinolone (Encort-A) 0.1%15g/Tube
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Topiramate in Neonates With Hypoxic Ischemic Encephalopathy Treated With Hypothermia
Status: COMPLETED
Conditions: Hypoxic Ischemic Encephalopathy
Interventions: DRUG: Topiramate in newborns with hypoxic ischemic encephalopathy treated with therapeutic hypothermia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of 8 Weeks of Treatment With the Combination of Moxifloxacin, PA-824 and Pyrazinamide in Patients With Drug Sensitive and Multi Drug-Resistant Pulmonary Tuberculosis (TB) (NC-002)
Status: COMPLETED
Conditions: Pulmonary Tuberculosis
Interventions: DRUG: Moxifloxacin (M)|DRUG: Pretomid (Pa)|DRUG: Pyrazinamide (Z)|DRUG: Rifafour
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adjunctive Treatment With Vitamin D3 in Patients With Active IBD
Status: SUSPENDED
Conditions: IBD|Inflammatory Bowel Diseases|Crohn Disease|Ulcerative Colitis|Vitamin D3 Deficiency
Interventions: DIETARY_SUPPLEMENT: Vitamin D3|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Role of Vitamin D Supplementation in Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Vitamin D3 cholecalciferol|DRUG: B Complex Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: OPTImal Treatment of Sinus VENOSUS Defect
Status: RECRUITING
Conditions: Sinus Venosus Defect|Congenital Heart Disease|Sinus Venosus Atrial Septum Defect
Interventions: DEVICE: OPTIMUS covered stent|PROCEDURE: Surgical correction of a SVD
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Combination of Traditional Chinese Medicine (TCM) and Highly Active Antiretroviral Therapy (HAART) on Immune Reconstitution of HIV/AIDS Patients
Status: UNKNOWN
Conditions: Acquired Immune Deficiency Syndrome Virus|HIV Infections
Interventions: DRUG: Fuzheng 3|DRUG: Fuzheng 1|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Influence of Interferential Current Therapy in the Treatment of Individuals With Shoulder Impact Syndrome: A Randomized, Placebo Controlled Clinical Trial.
Status: COMPLETED
Conditions: Shoulder Impingement Syndrome
Interventions: OTHER: exercise|DEVICE: Interferential current therapy|DEVICE: Therapeutic Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: VIVIFRAIL Program in Improving the Frailty and Physical Function in the Elderly
Status: RECRUITING
Conditions: Frailty|Physical Activity|Cognitive Function
Interventions: OTHER: Vivifrail
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Phase 1 Study of FOR46 in Patients With Metastatic Castration-Resistant Prostate Cancer (mCRPC)
Status: COMPLETED
Conditions: Prostate Cancer Metastatic
Interventions: DRUG: FOR46
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Alexis O-Ring Wound Retractor for the Prevention of Post-cesarean Surgical Site Infections
Status: COMPLETED
Conditions: Surgical Wound Infection
Interventions: DEVICE: Alexis O-Ring Wound Retractor|OTHER: Standard Surgical Retractors
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Body Mass Index and Post-dural Puncture Headache
Status: COMPLETED
Conditions: This Study Investigated the Influence of Body Mass Index (BMI) on PDPH in Elective Caesarean Section Patients in Whom 27G Spinal Needles Were Used
Interventions: PROCEDURE: spinal anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Romiplostim in Treating Hepatitis C-Infected Patients With Thrombocytopenia
Status: TERMINATED
Conditions: Hepatitis C Infection|Thrombocytopenia
Interventions: BIOLOGICAL: romiplostim|DRUG: ribavirin|OTHER: placebo|BIOLOGICAL: PEG-interferon alfa-2a|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Different Effects of Non-calcium Phosphate Binders on Serum Calcium
Status: COMPLETED
Conditions: Chronic Kidney Disease
Interventions: DRUG: Sevelamer Hydrochloride|DRUG: Lanthanum Carbonate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Integrated Treatment for Posttraumatic Stress Disorder and Substance Abuse in Young Adults
Status: COMPLETED
Conditions: Substance Use Disorder|Posttraumatic Stress Disorder
Interventions: BEHAVIORAL: Prolonged Exposure with Contingency Management|BEHAVIORAL: Standard Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy, and Safety Study of Optimized Background Antiretroviral Regimen (OB) in Combination With Enfuvirtide in the Treatment-Experienced Participants With Human Immunodeficiency Virus-1 (HIV-1) Infection
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Enfuvirtide|DRUG: Optimized background antiretroviral regimen (OB)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Immunotherapy of Adebrelimab With Apatinib and Tegafur for Immune Rechallenge Therapy in Esophageal Squamous Cell Carcinoma
Status: RECRUITING
Conditions: Locally Advanced or Metastatic Esophageal Squamous Cell Carcinoma
Interventions: DRUG: Adebrelimab|DRUG: Apatinib|DRUG: Tegafur
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High-Frequency Repetitive Transcranial Magnetic Stimulation Assists In Smoking Cessation
Status: COMPLETED
Conditions: Heavy Smoking
Interventions: DEVICE: Transcranial Magnetic Stimulation 10Hz|DEVICE: Magnetic stimulation using a special sham coil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Fosaprepitant for N/V With High-dose Interleukin-2 for Metastatic Melanoma and Renal Cell Carcinoma
Status: TERMINATED
Conditions: Chemotherapy-induced Nausea and Vomiting
Interventions: DRUG: Fosaprepitant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nitroglycerin Ointment for Preventing Bone Loss in Postmenopausal Women
Status: COMPLETED
Conditions: Osteoporosis|Osteopenia
Interventions: DRUG: Nitroglycerin ointment|DRUG: Calcium supplement with vitamin D
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: A Long-term Extension Study of Riociguat in Patients With Symptomatic Pulmonary Arterial Hypertension.
Status: RECRUITING
Conditions: Hypertension, Pulmonary
Interventions: DRUG: Adempas (Riociguat, BAY63-2521)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Pharmacokinetics of GNR-038 in Healthy Volunteers
Status: COMPLETED
Conditions: Hereditary Angioedema
Interventions: BIOLOGICAL: GNR-038, 25 МЕ/kg|BIOLOGICAL: GNR-038, 50 МЕ/kg|BIOLOGICAL: GNR-038, 100 МЕ/kg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study to Evaluate the Effect of Multiple Doses of Enzalutamide on the Pharmacokinetics of Substrates of P-glycoprotein (Digoxin) and Breast Cancer Resistant Protein (Rosuvastatin) in Male Subjects With Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: enzalutamide|DRUG: enzalutamide Placebo|DRUG: digoxin|DRUG: rosuvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combined Intravitreal Injection of Bevacizumab and Fasudil Versus Bevacizumab Alone for Macular Edema Secondary to Retinal Vein Occlusion in Previously Treated Patients
Status: UNKNOWN
Conditions: Retinal Vein Occlusion
Interventions: DRUG: injection bevacizumab|DRUG: injection Combined Bevacizumab and Fasudil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT