pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Comparison of a Polyvinyl Chloride Tube With a Wire-reinforced Tube for Tracheal Intubation Through the SaCoVLM
Status: RECRUITING
Conditions: Laparoscopic Surgery
Interventions: PROCEDURE: Polyvinyl Chloride Tube group|PROCEDURE: Wire-Reinforced Tube group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SCREENING
Clinical trial: Comparison of Two Gingival Displacement Procedures
Status: COMPLETED
Conditions: Gingival Retraction Techniques
Interventions: DEVICE: Aquasil Ultra Cordless, Dentsply|DEVICE: Ultrapak, Ultradent cord
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity Study of a Booster Dose of GSK Biologicals' 10-valent Pneumococcal Conjugate Vaccine
Status: COMPLETED
Conditions: Infections, Streptococcal
Interventions: BIOLOGICAL: 10 valent pneumococcal conjugate (vaccine)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Nasal Spray With Glucose Oxidase Preventing Common Cold in Pre-school Children
Status: COMPLETED
Conditions: Upper Respiratory Tract Infections
Interventions: DRUG: Placebo|DRUG: Glucose oxidase
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Beetroot Juice in Postmenopausal and Hypertensive
Status: COMPLETED
Conditions: Hypertension|Menopause
Interventions: OTHER: Exercise|DIETARY_SUPPLEMENT: Beetroot juice|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety Clinical Study of VC005 Tablets in Adult Patients With Moderate to Severe Atopic Dermatitis
Status: COMPLETED
Conditions: Moderate to Severe Atopic Dermatitis
Interventions: DRUG: VC005 tablets|DRUG: VC005 Tablets Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Acute High Altitude Exposure on Rescuer Performance and Patient Care
Status: NOT_YET_RECRUITING
Conditions: High Altitude|Hypobaric Hypoxia|Risk Reduction
Interventions: OTHER: Acute high altitude exposure|OTHER: Acute high altitude exposure, with supplementary oxygen|OTHER: Subacute high altitude exposure, after having spent a night at high altitude
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study in Healthy Men to Test How Different Doses of BI 1584862 Are Tolerated and How BI 1584862 is Taken up in the Body With or Without Food
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BI 1584862|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Osseodensifiction Versus Piezoelectric Internal Sinus Elevation Technique in Delayed Implant Placement
Status: COMPLETED
Conditions: Maxillary Sinus Floor Augmentation
Interventions: PROCEDURE: osseodensifiction internal sinus lift / sticky bone graft material|PROCEDURE: piezoelectric internal sinus lift / sticky bone graft material
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Open Latarjet Techniques Versus Arthroscopic Latarjet Techniques on Anterior Shoulder Instability: The Comparison of Clinical and Radiographic Outcomes
Status: UNKNOWN
Conditions: Shoulder Instability
Interventions: PROCEDURE: Open Latarjet technique|PROCEDURE: Arthroscopic Latarjet techniques
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Napabucasin (BBI-608) in Combination With FOLFIRI in Adult Patients With Previously Treated Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: Napabucasin|DRUG: Fluorouracil|DRUG: Leucovorin|DRUG: Irinotecan|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Superior Trunk Block Versus Interscalene Block for Post-operative Analgesia in Shoulder Surgeries
Status: COMPLETED
Conditions: Superior Trunk Block Versus Interscalene Block for Post-operative Analgesia in Shoulder Surgeries
Interventions: PROCEDURE: interscalene block|PROCEDURE: superior trunk block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Receptive Music Therapy for the Treatment of Depression
Status: COMPLETED
Conditions: Depression
Interventions: OTHER: Purpose designed music and sound listening program|OTHER: Sham music for depression
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Monotherapy of Itraconazole Versus Prednisolone in Allergic Bronchopulmonary Aspergillosis
Status: COMPLETED
Conditions: Allergic Bronchopulmonary Aspergillosis
Interventions: DRUG: Glucocorticoids|DRUG: Itraconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Shock Wave vs. On-demand Tadalafil for Erectile Dysfunction
Status: UNKNOWN
Conditions: Erectile Dysfunction
Interventions: DEVICE: LI-ESWT|DRUG: Tadalafil 20Mg Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Activity Study of Bevacizumab With Temozolomide ± Irinotecan for Neuroblastoma in Children
Status: ACTIVE_NOT_RECRUITING
Conditions: Neuroblastoma
Interventions: DRUG: Bevacizumab|DRUG: Temozolomide|DRUG: Temozolomide|DRUG: Irinotecan|DRUG: Bevacizumab|DRUG: Topotecan|DRUG: Temozolomide|DRUG: Dinutuximab Beta|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Monoclonal Antibody Against PCSK9 to Reduce Elevated LDL-C in Subjects Currently Not Receiving Drug Therapy for Easing Lipid Levels-2
Status: COMPLETED
Conditions: Hyperlipidemia
Interventions: BIOLOGICAL: Evolocumab|DRUG: Ezetimibe|BIOLOGICAL: Placebo to Evolocumab|OTHER: Placebo to Ezetimibe
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Medico-economic Evaluation of a Non-chirurgical Pulmonary Valve Replacement (REVALV)
Status: COMPLETED
Conditions: Dysfunction of the Prosthetic Conduct|Lesions of the Right Ventricular Outflow Tract
Interventions: DEVICE: Melody|DEVICE: bare stent|PROCEDURE: Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Dinaciclib in Combination With Rituximab in Participants With Chronic Lymphocytic Leukemia and Small Lymphocytic Lymphoma (P07974)
Status: COMPLETED
Conditions: Chronic Lymphocytic Leukemia|Small Lymphocytic Lymphoma
Interventions: DRUG: Dinaciclib|BIOLOGICAL: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Volume Increase Versus Supplemental 4% Articaine Buccal Infiltration on Mepivacaine Inferior Alveolar Nerve Block Success
Status: UNKNOWN
Conditions: Symptomatic Irreversible Pulpitis
Interventions: DRUG: 1.8 ml mepivacaine hydrochloride|DRUG: 3.6 ml mepivacaine hydrochloride|DRUG: 1.8 ml mepivacaine hydrochloride IANB plus 1.8 ml articaine hydrochloride BI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Clinical Study of CAR-T Treating Relapsed or Refractory T Cell Lymphoblastic Acute Leukemia/ Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: T-Cell Acute Lymphocytic Leukemia
Interventions: BIOLOGICAL: CD7 CAR-T
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Summers Non-Pesticide Lice Asphyxiator (L.A.)for the Treatment of Head Lice.
Status: COMPLETED
Conditions: Head Lice
Interventions: DRUG: Summers 5% L.A.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Impulse Oscillation to Evaluate Diagnostic Efficacy in Patients With Chronic Airway Disease
Status: UNKNOWN
Conditions: Chronic Airway Disease
Interventions: DIAGNOSTIC_TEST: impulse oscillation（IOS）|DIAGNOSTIC_TEST: bronchial provocation test(BPT)|DIAGNOSTIC_TEST: bronchial dilation test(BDT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effects of Knee Injections on Patients With Knee Osteoarthritis
Status: UNKNOWN
Conditions: Knee Osteoarthritis|Injection|Effect of Drug
Interventions: DRUG: Triamcinolone plus hyruan|DRUG: vitagen plus hyruan|DRUG: normal saline plus hyruan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects and Dose Response of Dexamethasone on Intercostal Blocks With Bupivicaine in Post Thoracic Surgery Patients
Status: UNKNOWN
Conditions: Pain
Interventions: DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Trial to Evaluate the Effect of ALN-PCSSC Treatment on Low Density Lipoprotein Cholesterol (LDL-C)
Status: COMPLETED
Conditions: Atherosclerotic Cardiovascular Disease|Familial Hypercholesterolemia|Diabetes
Interventions: DRUG: ALN-PCSSC|DRUG: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Armodafinil for Fatigue Associated With Taxanes Alone or in Combination With Other Agents
Status: TERMINATED
Conditions: Fatigue|Chemotherapy Side Effects
Interventions: DRUG: Armodafinil 150 mg/day|DRUG: Placebo,
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Famotidine on the Pharmacokinetics of Atazanavir When Coadministered to Participants With HIV Infection
Status: COMPLETED
Conditions: HIV
Interventions: DRUG: Atazanavir|DRUG: Atazanavir|DRUG: Ritonavir|DRUG: Ritonavir|DRUG: Tenofovir (TDF)|DRUG: Tenofovir (TDF)|DRUG: Nucleoside Reverse Transcriptase Inhibitor (NRTI)|DRUG: Nucleoside Reverse Transcriptase Inhibitor (NRTI)|DRUG: Famotidine (FAM)|DRUG: Famotidine (FAM)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Coenzyme Q10 Plus NADH Supplementation in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis
Status: COMPLETED
Conditions: Chronic Fatigue Syndrome
Interventions: DIETARY_SUPPLEMENT: Coenzyme Q10 plus NADH|DIETARY_SUPPLEMENT: phosphoserine plus vitamin C
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of Canakinumab to Treat Urticaria
Status: UNKNOWN
Conditions: Chronic Idiopathic Urticaria
Interventions: DRUG: Canakinumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase III Study of Neo-adjuvant Chemoradiotherapy Followed by Surgery for Squamous Cell Esophageal Cancer
Status: UNKNOWN
Conditions: Squamous Cell Esophageal Carcinoma
Interventions: PROCEDURE: Neo-adjuvant Chemoradiotherapy followed by Surgery|PROCEDURE: surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Evaluate CryoBalloon™ Ablation System in Patients Undergoing Esophagectomy
Status: COMPLETED
Conditions: Esophageal Cancer
Interventions: DEVICE: CryoBalloon Ablation System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Escalating Doses of Torisel in Combination With Three Chemotherapies Regimens: R-CHOP, R-FC or R-DHA for Patients With Relapsed/Refractory Mantle Cell Lymphoma (MCL).
Status: COMPLETED
Conditions: Mantle Cell Lymphoma Refractory
Interventions: DRUG: Torisel dose 15 mg and R-CHOP|DRUG: Torisel dose 15 mg and R-FC|DRUG: Torisel dose 15 mg and R-DHA|DRUG: Torisel dose 25 mg and R-CHOP|DRUG: Torisel dose 50 mg and R-CHOP|DRUG: Torisel dose 75 mg and R-CHOP|DRUG: Torisel dose 25 mg and R-FC|DRUG: Torisel dose 50 mg and R-FC|DRUG: Torisel dose 75 mg and R-FC|DRUG: Torisel dose 25 mg and R-DHA|DRUG: Torisel dose 50 mg and R-DHA|DRUG: Torisel 75 mg and R-DHA
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Deep Brain Stimulation of the Lateral Hypothalamus to Augment Motor Function of Patients With Spinal Cord Injury
Status: RECRUITING
Conditions: Deep Brain Stimulation|Neuro: Spinal Cord Injury
Interventions: PROCEDURE: Device implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 52-Week Efficacy and Safety Study of Ibodutant in Women With Irritable Bowel Syndrome With Diarrhea (IBS-D)
Status: TERMINATED
Conditions: Irritable Bowel Syndrome With Diarrhea
Interventions: DRUG: Ibodutant 10 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Fluoroscopy-guided Epidural Anesthesia for Osteoporotic Vertebral Compression Fracture Treated by Percutaneous Vertebroplasty
Status: UNKNOWN
Conditions: Vertebral Compression Fractures in Osteoporotic Patients
Interventions: OTHER: anesthesia combined with intravenous analgesia by remifentanil|OTHER: fluoroscopy-guided epidural anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Facilitating HIV Testing Among Young Adult MSM Through Social Networking
Status: COMPLETED
Conditions: HIV
Interventions: DEVICE: Rapid HIV Self-Test (OraQuick® In-home HIV Test)|DEVICE: Conventional Home-Based HIV Test (Home Access Express)|OTHER: Community/Medical-Based HIV Test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Effects of Low-Dose Doxycycline on Oral Bone Loss
Status: COMPLETED
Conditions: Periodontitis
Interventions: DRUG: 20 mg doxycycline hyclate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Reversing Therapy Resistance With Epigenetic-Immune Modification
Status: TERMINATED
Conditions: Breast Neoplasms
Interventions: DRUG: Tamoxifen|DRUG: Vorinostat|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Albumin-bound Paclitaxel Combined With Cisplatin Versus Docetaxel Combined With Cisplatin Induced Chemotherapy in Advanced Head and Neck Squamous Tummor
Status: UNKNOWN
Conditions: Squamous Cell Carcinoma of Head and Neck
Interventions: DRUG: albumin-bound paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fludeoxyglucose F 18-PET/CT Imaging in Assessing Response to Chemotherapy in Patients With Newly Diagnosed Stage II, Stage III, or Stage IV Hodgkin Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: BIOLOGICAL: bleomycin sulfate|BIOLOGICAL: filgrastim|BIOLOGICAL: pegfilgrastim|DRUG: cyclophosphamide|DRUG: dacarbazine|DRUG: doxorubicin hydrochloride|DRUG: etoposide|DRUG: prednisolone|DRUG: procarbazine hydrochloride|DRUG: vinblastine sulfate|DRUG: vincristine sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pazopanib Hydrochloride in Treating Patients With Von Hippel-Lindau Syndrome
Status: COMPLETED
Conditions: Von Hippel-Lindau Syndrome
Interventions: OTHER: Laboratory Biomarker Analysis|DRUG: Pazopanib Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Ultra-fraction Radiotherapy Bridging CART in R/R DLBCL
Status: RECRUITING
Conditions: Diffuse Large B Cell Lymphoma|CAR-T|Radiotherapy|Bridging Therapy
Interventions: RADIATION: ultra-fraction radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nasal Versus Venous Lorazepam for Control of Acute Seizures in Children
Status: COMPLETED
Conditions: Status Epilepticus|Seizures
Interventions: DRUG: Lorazepam|DRUG: Lorazepam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rotational Narrow Strip Versus Full Conjunctival Graft in Pterygium Excision
Status: COMPLETED
Conditions: Pterygium
Interventions: PROCEDURE: Rotational Narrow Strip Conjunctival Graft|PROCEDURE: Full Conjunctival Graft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Zero-fluoroscopic Navigation Versus Conventional Fluoroscopic Navigation for Double-chamber Pacemaker Implantation
Status: UNKNOWN
Conditions: Sick Sinus Syndrome|Complete Atrioventricular Block|High Degree Second Degree Atrioventricular Block (Disorder)|Bradycardia
Interventions: PROCEDURE: zero-fluoroscopy 3D navigation|PROCEDURE: conventional x-ray navigation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Tesetaxel Every 3 Weeks vs Weekly vs Capecitabine as 1st-line Therapy for Locally Advanced or Metastatic Breast Cancer
Status: UNKNOWN
Conditions: Locally Advanced Non-resectable Breast Cancer|Metastatic Breast Cancer
Interventions: DRUG: Tesetaxel|DRUG: Tesetaxel|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intranasal Dexmedetomidine and Zolpidem for Treatment of Primary Insomnia
Status: RECRUITING
Conditions: Insomnia
Interventions: DRUG: Dexmedetomidine|DRUG: Zolpidem|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Intensive Upper and Lower Limbs Motor Control Therapy in Cerebral Palsy Children
Status: COMPLETED
Conditions: Cerebral Palsy
Interventions: OTHER: Intensive bimanual therapy|OTHER: Intensive neurodevelopmental therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The LAVA (Lateral Flow Antigen Validation and Applicability) 2 Study for COVID-19
Status: COMPLETED
Conditions: SARS-CoV-2 Infection
Interventions: DIAGNOSTIC_TEST: Innova Lateral Flow Test
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: PERFECT Project - Part 2 - Study 2
Status: COMPLETED
Conditions: Diabetes Prevention|Obesity Prevention
Interventions: OTHER: Control|OTHER: Pea protein|OTHER: Pea Starch|OTHER: Pea fibre + pea starch|OTHER: Pea protein + pea starch|OTHER: Pea fibre + pea starch + pea protein
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of the Effectiveness and Safety of Galantamine Hydrobromide on Cognitive Impairment in Patients With Schizophrenia.
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Extended-release galantamine hydrobromide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: VL-2397 Compared to Standard First-Line Treatment for Invasive Aspergillosis (IA) in Adults
Status: TERMINATED
Conditions: Invasive Aspergillosis|Invasive Pulmonary Aspergillosis
Interventions: DRUG: Investigational Agent: VL-2397|DRUG: Standard treatment: Voriconazole, Isavuconazole, or Liposomal amphotericin B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rehabilitative BCI in Acute Ischemic Stroke
Status: UNKNOWN
Conditions: Stroke, Acute
Interventions: DEVICE: Non-invasive BCI training|OTHER: Traditional Physiotherapy protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluate Safety and Explore Efficacy of FURESTEM-OA Kit Inj. in Patients With Knee Osteoarthritis
Status: NOT_YET_RECRUITING
Conditions: Knee Osteoarthritis
Interventions: BIOLOGICAL: FURESTEM-OA Kit Inj.|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Extracorporeal Shockwave Therapy for the Treatment of Refractory Angina Pectoris
Status: COMPLETED
Conditions: Refractory Angina Pectoris
Interventions: DEVICE: Cardiac Extracorporeal Shockwave Therapy generator (Cardiospec)|DEVICE: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Nebulized Epinephrine in Asthma Exacerbation in Pediatric Age Group With the Standard Treatment Compared to Standard Treatment Using Improvement PRAM Score as a Primary Outcome
Status: RECRUITING
Conditions: Shortness of Breath|Asthma in Children|Epinephrine Causing Adverse Effects in Therapeutic Use|Salbutamol Adverse Reaction
Interventions: DRUG: nebulized epinephrine|DRUG: Salbutamol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Extending taVNS Paired With Infant CIMT Into a Home-Based Setting
Status: COMPLETED
Conditions: Cerebral Palsy
Interventions: COMBINATION_PRODUCT: Custom EMG triggered Soterix taVNS stimulation with CIMT therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Proxalutamide Treatment for COVID-19 Patients in Intensive Care Unit
Status: WITHDRAWN
Conditions: Covid19|SARS (Severe Acute Respiratory Syndrome)
Interventions: DRUG: Proxalutamide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combined Atropine With Orthokeratology in Childhood Myopia Control (AOK) -A Randomized Controlled Trial
Status: COMPLETED
Conditions: Myopia
Interventions: DRUG: 0.01% atropine eye drops|DEVICE: ortho-k
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Food on the Pharmacokinetics of NNC0123-0000-0338 in a Tablet Formulation in Healthy Subjects
Status: COMPLETED
Conditions: Diabetes|Healthy
Interventions: DRUG: insulin 338 (GIPET I)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Methoxyflurane for Treatment of Incident Pain
Status: COMPLETED
Conditions: Pain Measurement
Interventions: DRUG: Methoxyflurane|DRUG: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Gly16Arg Polymorphism in ADRB2 Gene on Asthma Control in Children Receiving Long Acting Beta Agonists
Status: WITHDRAWN
Conditions: Safety of Long Acting Beta Agnoists
Interventions: DRUG: open-labeled inhaled corticosteroids (ICS); FORADIL® AEROLIZER®|DRUG: foradil placebo|DRUG: foradil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Mechanism of Cardiac and Cerebral Function Injury Caused by Intraoperative Limb Ischemia-reperfusion
Status: RECRUITING
Conditions: Ischemic Reperfusion Injury
Interventions: DRUG: Dexmedetomidine|DRUG: 0.9% Sodium chloride|DEVICE: Tourniquet(Early)|DEVICE: Tourniquet(Late)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Application of Needle-free Injection of Insulin in Patients With Gestational Diabetes Mellitus
Status: RECRUITING
Conditions: Injection|Blood Glucose, High|Glycemic Control|Gestational Diabetes
Interventions: DEVICE: Needle-free injection device, Then traditional insulin pen|DEVICE: Traditional insulin pen , Then Needle-free injection device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: 3T MRI Biomarkers of Glioma Treatment Response
Status: TERMINATED
Conditions: Adult Anaplastic Astrocytoma|Adult Anaplastic Ependymoma|Adult Anaplastic Oligodendroglioma|Adult Giant Cell Glioblastoma|Adult Glioblastoma|Adult Gliosarcoma|Recurrent Adult Brain Tumor
Interventions: DEVICE: 3-Tesla magnetic resonance imaging|DEVICE: CEST-MRI|DEVICE: DW-MRI|DEVICE: DCE-MRI|DEVICE: DSC-MRI|DRUG: IV administration of gadolinium-containing contrast agent
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparative Study of Radiotherapy Treatments to Treat High Risk Prostate Cancer Patients
Status: RECRUITING
Conditions: Prostate Cancer
Interventions: RADIATION: EBRT + HDR brachytherapy boost|RADIATION: Hypofractionated Dose Escalation Radiotherapy|DRUG: Androgen deprivation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Inhibiting Telomerase to Reverse Trastuzumab Resistance in HER2+ Breast Cancer
Status: COMPLETED
Conditions: Breast Neoplasms
Interventions: DRUG: GRN163L in combination with trastuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Dose Escalation Study Of PF-06939999 In Participants With Advanced Or Metastatic Solid Tumors
Status: TERMINATED
Conditions: Advanced Solid Tumors|Metastatic Solid Tumors
Interventions: DRUG: PF-06939999 dose escalation|DRUG: PF-06939999 monotherapy|DRUG: PF-06939999 in combination with docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Validation of the Russian and Kazakh Versions of the Beck Depression Inventory and Beck Anxiety Inventory
Status: COMPLETED
Conditions: Depression|Anxiety|Breast Cancer|Ovarian Cancer|Cervical Cancer|Lung Cancer|Colon Cancer
Interventions: OTHER: Beck Depression Inventory-21 (diagnostic survey)|OTHER: Beck Anxiety Inventory|OTHER: Interview using The International Classification of Diseases in tenth edition (ICD-10) criteria
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Assess the Bioequivalence of Darunavir When Co-Administrated With Cobicistat Under Fed and Fasted Conditions
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DRUG: darunavir|DRUG: cobicistat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multicenter Trial Comparing Multi-course Chemotherapy in Locoregionally Advanced Nasopharyngeal Carcinoma
Status: UNKNOWN
Conditions: Nasopharyngeal Carcinoma
Interventions: DRUG: neoadjuvant chemotherapy plus concurrent chemoradiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exploratory Study to Estimate the Prophylactic Efficacy of Palivizumab in Healthy Adult Participants Inoculated With RSV
Status: COMPLETED
Conditions: Healthy Adult Participants
Interventions: DRUG: Palivizumab|DRUG: Placebo|OTHER: RSV-A Memphis 37b virus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Early Supportive Care and Nutritional Support in Adults With Pancreatic Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Pancreatic Cancer
Interventions: BEHAVIORAL: Fitbit Data Collection|BEHAVIORAL: Nutrition Counseling|BEHAVIORAL: Fact G Survey|BEHAVIORAL: General Anxiety Disorder (GAD)-7|BEHAVIORAL: Patient Health Questionnaire (PHQ)-9
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of Mobilization With Movement in Individuals With Shoulder Impingement Syndrome
Status: COMPLETED
Conditions: Shoulder Impingement Syndrome|Subacromial Impingement|Subacromial Impingement Syndrome|Subacromial Pain Syndrome|Impingement Syndrome, Shoulder
Interventions: OTHER: Mobilization with movement|OTHER: Conventional physical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transversus Abdominis Plane Block in Microsurgical Breast Recon w/Abdominal Free Flap in Breast CA
Status: COMPLETED
Conditions: Breast - Female
Interventions: PROCEDURE: Transversus Abdominis Plane (TAP) block|DEVICE: Nimbus Infusion Pump IV Administration|DRUG: Bupivacaine infusion|DRUG: Acetominophen|DRUG: Hydromorphone|DRUG: Oxycodone|DRUG: Ondansetron
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Psychophysiological Study of Pain Perception in Depressed Patients With Suicidal Risk
Status: RECRUITING
Conditions: Major Depressive Disorder
Interventions: BEHAVIORAL: Painful stimulations of major depressive patients|BIOLOGICAL: Blood sample|DIAGNOSTIC_TEST: Clinical assessment|BEHAVIORAL: Social touch
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Radiation Therapy With or Without Combination Chemotherapy in Treating Patients With Advanced Cancer of the Oropharynx or Hypopharynx
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: DRUG: cisplatin|DRUG: fluorouracil|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Phase II Trial of Weekly or Every 3-week Ixabepilone for Patients With Metastatic Breast Cancer
Status: COMPLETED
Conditions: Metastatic Breast Cancer
Interventions: DRUG: Ixabepilone|DRUG: Ixabepilone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Psilocybin (TRP-8802) in the Treatment of Binge Eating Disorder
Status: ACTIVE_NOT_RECRUITING
Conditions: Binge Eating Disorder
Interventions: DRUG: TRYP-0082|BEHAVIORAL: Psychotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stimulation Galvanique Vestibulaire
Status: TERMINATED
Conditions: Hypertensive Hemorrhage of Right Parietal Lobe
Interventions: DEVICE: galvanic vestibular stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Mild Intermittent Hypoxia: A Prophylactic for Autonomic Dysfunction in Individuals With Spinal Cord Injuries
Status: RECRUITING
Conditions: Spinal Cord Injuries|Autonomic Dysreflexia
Interventions: OTHER: Mild Intermittent Hypoxia|OTHER: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy Evaluation of Shen Cao Gan Jiang Tang on Mild and Moderate COVID-19 Patients
Status: COMPLETED
Conditions: COVID-19 Respiratory Infection|Herbal Medicine
Interventions: DRUG: Shen Cao Gan Jiang Tang (Gan Cao Gan Jiang Tang with Ginseng)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Team Approach to Polypharmacy Evaluation and Reduction
Status: RECRUITING
Conditions: Multi-morbidity|Medication Therapy Management|Polypharmacy
Interventions: OTHER: Medication reduction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: FIasp® vs. Novolog® in Type 1 Diabetics Using 670G Medtronic Pump
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus
Interventions: DRUG: Fiasp®|DRUG: Novolog®|DEVICE: 670G hybrid closed loop continuous subcutaneous insulin infusion system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of MRx0518 and Avelumab in Patients With Urothelial Carcinoma
Status: WITHDRAWN
Conditions: Urothelial Carcinoma
Interventions: DRUG: MRx0518|BIOLOGICAL: Avelumab 20 mg/mL Intravenous Solution (IV)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assess Bronchodilator Effect QVM149 Dosed Either in the Morning or Evening Compared to Placebo in Patients With Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Treatment A: Matching placebo (morning dose) and QVM149 150/50/80 μg (evening dose)|DRUG: Treatment B: QVM149 150/50/80 μg (morning dose) and matching placebo (evening dose)|DRUG: Treatment C: Placebo (morning dose) and placebo (evening dose)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dorsal Root Ganglion Stimulation for the Treatment of Arthritic Knee Pain
Status: UNKNOWN
Conditions: Knee Osteoarthritis|Knee Pain Chronic|Knee Arthritis|Knee Arthropathy
Interventions: DEVICE: Dorsal Root Ganglion Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Value of Prednisolone With Aspirin Before Embryo Transfer in Intracytoplasmic Sperm Injection (ICSI) Cycles
Status: COMPLETED
Conditions: Infertility
Interventions: DRUG: prednisolone|DRUG: Acetyl Salicylic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: In-office Evaluation of Two Toric Soft Contact Lenses and a Spherical Soft Contact Lens
Status: COMPLETED
Conditions: Astigmatism
Interventions: DEVICE: senofilcon A toric contact lens|DEVICE: alphafilcon A toric|DEVICE: etafilcon A sphere
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Multicenter, Double-blind, Randomized, Parallel-group, Pilot Study of 12-week Duration to Assess the Short-term Safety and Tolerability of Lorcaserin Plus Two Doses of Immediate-Release Phentermine-HCl Compared With Lorcaserin Alone in Overweight and Obese Adults
Status: COMPLETED
Conditions: Chronic Weight Management
Interventions: DRUG: lorcaserin + phentermine placebo|DRUG: lorcaserin + phentermine-HCl + phentermine placebo|DRUG: lorcaserin + phentermine-HCl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A 2 Weeks Study to Evaluate Tolerability, Safety, Permanence on the Ocular Surface and Efficacy of Two Concentrations of Lubricin Eye Drops Versus Sodium Hyaluronate 0.18% Eye Drops in Patients With Ocular Discomfort Following Refractive Surgery
Status: COMPLETED
Conditions: Ocular Discomfort
Interventions: DEVICE: Lubricin 20µg/ml eye drops|DEVICE: Lubricin 50µg/ml eye drops|DEVICE: Sodium hyaluronate (HA) 0.18% eye drops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: PHARM-S.A.V.E.S: Suicide Prevention Training
Status: COMPLETED
Conditions: Suicide
Interventions: BEHAVIORAL: Pharm-SAVES|BEHAVIORAL: Interactive video cases
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: PLATINUM Trial to Assess the PROMUS Element Stent System for Treatment of De Novo Coronary Artery Lesions-Pharmacokinetics (PLATINUM PK)
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DEVICE: PROMUS Element Everolimus-Eluting Coronary Stent System|DRUG: Aspirin|DRUG: Thienopyridine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gastric Bypass, Gastric Band or Sleeve Gastrectomy to Treat Obesity
Status: COMPLETED
Conditions: Obesity|Surgery|Quality of Life|Weight Loss
Interventions: PROCEDURE: Gastric Band|PROCEDURE: Gastric Bypass|PROCEDURE: Sleeve Gastrectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exercise vs. Topical Diclofenac vs. PRP
Status: NOT_YET_RECRUITING
Conditions: Gonarthrosis
Interventions: OTHER: Exercise|OTHER: Topical Diclofenac|OTHER: Platelet-Rich-Plasma (PRP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Adderall XR Compared With Concerta in Treating Young Cancer Patients With Memory, Attention, and Depression
Status: TERMINATED
Conditions: Depression|Neurotoxicity|Unspecified Childhood Solid Tumor, Protocol Specific
Interventions: DRUG: Adderall-XR®|DRUG: Concerta®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Placebo In Chronic Back Pain - Double-Blind Randomized Control Trial
Status: COMPLETED
Conditions: Chronic Low Back Pain
Interventions: DRUG: Naproxen|DRUG: Placebo|DRUG: Omeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Fluoxetine in KCNC1-related Disorder
Status: ENROLLING_BY_INVITATION
Conditions: KCNC1 Related Disorder|Genetic Disease|Rare Diseases
Interventions: DRUG: Fluoxetine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Research Study Looking at a Single Dose of Etavopivat in Healthy Chinese Participants
Status: RECRUITING
Conditions: Healthy Volunteers|Sickle Cell Disease|Thalassemia
Interventions: DRUG: Etavopivat
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testing AZD1775 as a Potential Targeted Treatment in Cancers With BRCA Genetic Changes (MATCH-Subprotocol Z1I)
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Lymphoma|Advanced Malignant Solid Neoplasm|Hematopoietic and Lymphoid Cell Neoplasm|Refractory Lymphoma|Refractory Malignant Solid Neoplasm|Refractory Multiple Myeloma
Interventions: DRUG: Adavosertib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Citrate Dialysate on Clot Formation and Anemia in Hemodialysis Patients
Status: COMPLETED
Conditions: Hemodialysis|Citrate|Heparin
Interventions: DEVICE: Citrate dialysate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: New Compression Hosiery Versus Standard Class II Compression Stockings After Endothermal Ablation
Status: COMPLETED
Conditions: Varicose Veins|Vascular Diseases
Interventions: DEVICE: Short stocking|DEVICE: Usual stocking
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Efficacy and Safety of INC280 in Patients With Advanced Hepatocellular Carcinoma.
Status: TERMINATED
Conditions: Advanced Hepatocellular Carcinoma With c-MET Dysregulation
Interventions: DRUG: INC280
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of Kinesio Taping in Patients With Knee Osteoarthritis
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: PROCEDURE: KINESIO TAPING|DEVICE: CONVENTIONAL PHYSICAL THERAPY
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prevalence of Chronic Thromboembolic Pulmonary Hypertension After Acute Pulmonary Embolism : (Preva-CTEPH)
Status: COMPLETED
Conditions: Chronic Thromboembolic Pulmonary Hypertension (CTEPH)|Pulmonary Embolism
Interventions: DIAGNOSTIC_TEST: Study population
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Role Of Sensitivity to neuroEndocrine Systems in Social Decisions
Status: WITHDRAWN
Conditions: Borderline Personality Disorder
Interventions: DRUG: Hydrocortisone|DIETARY_SUPPLEMENT: Yohimbine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Safety Evaluation of Anti-Caries Varnish
Status: COMPLETED
Conditions: Dental Caries in Children
Interventions: DRUG: Test varnish|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Gastric Cancer Prevention in the Family Members by Helicobacter Pylori Eradication
Status: ACTIVE_NOT_RECRUITING
Conditions: Gastric Cancer|Helicobacter Pylori Infection|Family Members
Interventions: DRUG: Placebo|DRUG: LAC triple therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pharmacokinetics and Relative Bioavailability of 11634 Immediate Release Tablet in Healthy Male Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BI 11634 tablet|DRUG: BI 11634 drinking solution
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PD and Safety of TG-0054 Combined With G-CSF in Multiple Myeloma, Non-Hodgkin Lymphoma and Hodgkin Disease Patients
Status: COMPLETED
Conditions: Multiple Myeloma|Non-Hodgkin Lymphoma|Hodgkin Disease
Interventions: DRUG: TG-0054 combined with G-CSF
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bandebereho Father Groups Randomized Control Trial in Rwanda
Status: COMPLETED
Conditions: Gender Relations|Prenatal Care|Partner Communication|Contraception|Violence
Interventions: BEHAVIORAL: MenCare+/Bandebereho fathers'/couples' group education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of JNS002 (Doxorubicin Hydrochloride Liposome Injection) in Relapsed or Refractory Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: JNS002
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Guided Bone Regeneration Using Synthetic Membrane
Status: UNKNOWN
Conditions: Jaw, Edentulous|Jaw, Edentulous, Partially
Interventions: DEVICE: Regenecure AMCA GBR Dental Membrane|DEVICE: Geistlich Bio-Gide® collagen membrane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT