pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: The Use of the Prevena Incision Management System (PIMS) on Closed Incisions in Renal Transplant Subjects
Status: TERMINATED
Conditions: Surgical Site Reaction
Interventions: DEVICE: Prevena Incision Management System|OTHER: Standard of Care for Surgical Incisions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Melphalan, Peripheral Stem Cell Transplantation, and Interleukin-2 Followed by Interferon Alfa in Treating Patients With Advanced Multiple Myeloma
Status: COMPLETED
Conditions: Refractory Multiple Myeloma|Stage I Multiple Myeloma|Stage II Multiple Myeloma|Stage III Multiple Myeloma
Interventions: DRUG: melphalan|BIOLOGICAL: recombinant interferon alfa|BIOLOGICAL: aldesleukin|PROCEDURE: in vitro-treated peripheral blood stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Pilot Study of Foscarnet Cream in the Treatment of Mucocutaneous Herpes Simplex Virus Infections in Immunocompromised Patients Unresponsive to Acyclovir Treatment
Status: COMPLETED
Conditions: Herpes Simplex|HIV Infections
Interventions: DRUG: Foscarnet sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: A Study to Describe the Breast Cancer Patient Population, Treatment, and Results in Indian Patients Receiving Combinations of the Medicines Called Palbociclib for Advanced Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer|Breast Carcinoma|Breast Neoplasms|Breast Tumors|Cancer of Breast
Interventions: DRUG: Palbociclib plus hormonal treatment - first line treatment|DRUG: Palbociclib plus hormonal treatment - second line treatment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Study of Qishenyiqi Drop Pills in Improving the Prognosis of Heart Failure Patients
Status: UNKNOWN
Conditions: Heart Failure
Interventions: DRUG: Qishenyiqi dropping pills|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Endotracheal Intracuff Pressure Between Two Cuff Sealing Methods
Status: COMPLETED
Conditions: Endotracheal Tube
Interventions: PROCEDURE: MOVT|PROCEDURE: VE/VI ratio of Spirometer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Creatine Monohydrate on Functional Muscle Strength in Children With FSHD
Status: COMPLETED
Conditions: Facio-Scapulo-Humeral Dystrophy|FSHD2|FSHD1
Interventions: DIETARY_SUPPLEMENT: Creatine Monohydrate|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Predictive Value of Dynamic Combination of BNP and NGAL for the Prognosis of Patients With Sepsis
Status: COMPLETED
Conditions: 28-day Mortality|Sepsis
Interventions: OTHER: BNP and NGAL
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: A Clinical Study to Evaluate TV003 in Healthy Adults in Taiwan
Status: COMPLETED
Conditions: Dengue
Interventions: BIOLOGICAL: TV003|BIOLOGICAL: Placebo for TV003
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Hybrid Type II Trial of the Optimizing Resilience and Coping With HIV Through Internet Delivery in Ryan White Clinics in Chicago
Status: RECRUITING
Conditions: People Living With HIV
Interventions: BEHAVIORAL: BHS+ORCHID
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Analysis of the Link Between Flow State and Preoperative Anxiety in Children Undergoing Playful Distraction
Status: COMPLETED
Conditions: Children|Ambulatory Surgery|General Anesthesia
Interventions: BEHAVIORAL: Video game|BEHAVIORAL: Animated cartoon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Phase IV Vaccine Study Under the National Cohort Study of Effectiveness and Safety of SARS-CoV-2 (COVID-19) Vaccines.
Status: COMPLETED
Conditions: SARS CoV 2 Infection
Interventions: BIOLOGICAL: Johnson & Johnson
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Safety and Efficacy of Metronomic Cyclophosphamide, Metformin and Olaparib in Endometrial Cancer Patients
Status: COMPLETED
Conditions: Recurrent Endometrial Cancer
Interventions: DRUG: Olaparib|DRUG: metformin|DRUG: metronomic cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Dose-Finding Study of DTX301 (scAAV8OTC) in Adults With Late-Onset Ornithine Transcarbamylase (OTC) Deficiency
Status: COMPLETED
Conditions: Ornithine Transcarbamylase (OTC) Deficiency
Interventions: GENETIC: scAAV8OTC|DRUG: Reactive Corticosteroid Taper Regimen|DRUG: Prophylactic Corticosteroid Taper Regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: REST - Replacing Steroids in the Transplant Ineligble
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: Isatuximab, bortezomib, lenalidomide, dexamethason
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dosage-Escalation Study of the Safety and Immunogenicity of a Novel Rabies Vaccine ChAd155-RG vs. the Comparator RABAVERT Vaccine in Healthy Adult Subjects
Status: COMPLETED
Conditions: Rabies|Rabies Immunisation
Interventions: BIOLOGICAL: ChAd155-RG|OTHER: Placebo|BIOLOGICAL: Rabies Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: CRISPR-Edited Allogeneic Anti-CLL-1 CAR-T Cell Therapy in Patients With Relapsed/Refractory Acute Myeloid Leukemia
Status: RECRUITING
Conditions: Acute Myeloid Leukemia, in Relapse|Acute Myeloid Leukemia Refractory
Interventions: DRUG: CB-012
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Can Intrauterine Levonorgestrel Releasing Device Be a Treatment Option for Postmenstrual Spotting in Isthmocele
Status: COMPLETED
Conditions: Isthmocele|Post-menstrual Spotting Bleeding|Pelvic Pain
Interventions: DEVICE: usage of mirena ( levonorgestrel releasing intrauterine device) in isthmocele|DRUG: Levonorgestrel Drug Implant Product
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Bivalirudin Versus Heparin/ GP IIB/IIA in Patients Undergoing PCI
Status: UNKNOWN
Conditions: Coronary Artery Disease
Interventions: PROCEDURE: Percutaneous Coronary Intervention (PCI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: BIPAP Vision Versus OPTIFLOW System Comparison in Acute Respiratory Failure After Cardio Thoracic Surgery
Status: COMPLETED
Conditions: Respiratory Insufficiency
Interventions: DEVICE: Non invasive ventilation (VNI)|DEVICE: Non invasive ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Tennis Ball on Balance and Quality of Life in Cancer Patients With Neuropathy.
Status: ENROLLING_BY_INVITATION
Conditions: Cancer|Neuropathy|Therapy-Associated Cancer
Interventions: OTHER: myofascial release with tennis ball
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Compare How the Study Medicine (PF-07923568) is Processed in Participants With Different Levels of Loss of Liver Function to Healthy Participants.
Status: COMPLETED
Conditions: Liver Diseases|Hepatic Impairment
Interventions: DRUG: PF-07923568
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study Of PF-05280014 Or Trastuzumab Plus Taxotere® And Carboplatin In HER2 Positive Breast Cancer In The Neoadjuvant Setting (REFLECTIONS B327-04)
Status: COMPLETED
Conditions: Early Breast Cancer
Interventions: BIOLOGICAL: PF-05280014|DRUG: Taxotere®|DRUG: Paraplatin®|BIOLOGICAL: Trastuzumab-EU|DRUG: Taxotere®|DRUG: Paraplatin®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dosing of Brentuximab Vedotin for Mycosis Fungoides, Sezary Syndrome Patients
Status: RECRUITING
Conditions: Mycosis Fungoides|Lymphomatoid Papulosis|Sezary Syndrome
Interventions: DRUG: brentuximab vedotin|DRUG: brentuximab vedotin|DRUG: brentuximab vedotin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CAPOXIRI+Bevacizumab vs. FOLFOXIRI+Bevacizumab for mCRC
Status: UNKNOWN
Conditions: Metastatic Colorectal Cancer
Interventions: BIOLOGICAL: Bevacizumab|DRUG: 5-fluorouracil|DRUG: Leucovorin calcium|DRUG: Irinotecan hydrochloride|DRUG: Oxaliplatin|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endoscopic Sleeve Gastroplasty Technique Comparison for Weight Loss
Status: NOT_YET_RECRUITING
Conditions: Obesity|Obesity, Morbid|Metabolic Disease|Weight, Body
Interventions: DEVICE: Endoscopic Sleeve Gastroplasty - Belt and Suspenders|DEVICE: Endoscopic Sleeve Gastroplasty - Belt
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Progress of Mild Alzheimer's Disease in Participants on Acupuncture Versus Sham Acupuncture
Status: RECRUITING
Conditions: Alzheimer Disease 1
Interventions: DEVICE: Active acupuncture|DEVICE: Sham acupuncture|DRUG: Donepezil Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Smart Technology Facilitated Patient-centered Venous Thromboembolism Management
Status: NOT_YET_RECRUITING
Conditions: Venous Thromboembolism|Digital Health|Health Education
Interventions: DEVICE: mobile venous thromboembolism application (mVTEA)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Comparison of Exparel to Bupivacaine in TAP Block for Abdominal Gynecologic Surgery
Status: UNKNOWN
Conditions: Gynecologic Cancer|Post Operative Pain
Interventions: DRUG: Bupivacaine|DRUG: liposomal bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 3 Efficacy Study of LNZ101 for the Treatment of Presbyopia
Status: COMPLETED
Conditions: Presbyopia|Near Vision|Miosis|Eye Diseases
Interventions: DRUG: Aceclidine+Brimonidine combination ophthalmic solution|DRUG: Aceclidine|DRUG: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trazodone Dose Tolerance and APAP Adherence
Status: SUSPENDED
Conditions: Sleep Apnea, Obstructive
Interventions: DRUG: Trazodone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Evaluate the Safety and Efficacy of ATR-002 in Adult Hospitalized Patients With COVID-19
Status: TERMINATED
Conditions: COVID-19
Interventions: DRUG: ATR-002|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of Pioglitazone for the Treatment of Moderate to Severe Asthma in Obese Asthmatics (Glitz Asthma)
Status: TERMINATED
Conditions: Asthma|Obesity
Interventions: DRUG: Pioglitazone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Single Ascending Dose and Multiple Ascending Dose Study of Niclosamide Inhalation Powder in Healthy Adult Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Niclosamide Inhalation Powder|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Inetetamab in Combination With Pyrotinib in HER2 Mutant or Amplified Advanced Non-small Cell Lung Cancer
Status: RECRUITING
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: inetetamab|DRUG: Pytotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intramedullary Nail Versus Sliding Hip Screw Inter-Trochanteric Evaluation
Status: COMPLETED
Conditions: Femoral Neck Fractures|Intertrochanteric Fracture
Interventions: PROCEDURE: Gamma3 Intramedullary Nails (Stryker)|PROCEDURE: Sliding Hip Screws
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A First Time in Man Study to Asses the Safety and Tolerability of AZD7624 in Healthy Subjects
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: DRUG: AZD7624|DRUG: Placebo to match
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Computerized Decision Support to Increase Detection of Chronic Thromboembolic Pulmonary Hypertension in Patients With Prior Pulmonary Embolism
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Thromboembolic Pulmonary Hypertension
Interventions: BEHAVIORAL: On-screen computerized decision support alert
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SCREENING
Clinical trial: DHA Brain Delivery Trial
Status: COMPLETED
Conditions: Brain DHA Delivery and Alzheimer's Disease Risk
Interventions: DRUG: DHA|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Investigating the Effectiveness of Vibration Therapy on Sarcopenia in Osteoarthritis Knee Patients
Status: RECRUITING
Conditions: Knee Arthropathy|Osteoarthritis, Knee|Knee Osteoarthritis
Interventions: DEVICE: Vibration Therapy|COMBINATION_PRODUCT: Physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety/Tolerability Study of Arikayce™ in Cystic Fibrosis Patients With Chronic Infection Due to Pseudomonas Aeruginosa
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: Arikayce™ 560 mg|DRUG: Placebo for 560 mg|DRUG: Arikayce™ 70 mg|DRUG: Arikayce™ 140 mg|DRUG: Placebo for 70 mg / 140 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MTD Study PXD-101 in Combination With Paclitaxel + Carboplatin in Chemotherapy-Naive Patients With Stage IV NSCLC
Status: COMPLETED
Conditions: Stage IV Non-small Cell Lung Cancer
Interventions: DRUG: Belinostat, Carboplatin, Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mini-dose Esketamine-dexmedetomidine Supplemented Analgesia and Long-term Outcomes
Status: ACTIVE_NOT_RECRUITING
Conditions: Scoliosis Correction|Postoperative Analgesia|Esketamine|Dexmedetomidine|Chronic Postsurgical Pain
Interventions: DRUG: Esketamine|DRUG: Dexmedetomidine|DRUG: Sufentanil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Intercostal Nerve Block With Local Anesthesia Administered Via Incision-specific Multi-site Injection for Thoracic Surgery
Status: NOT_YET_RECRUITING
Conditions: Intercostal Nerve Block
Interventions: PROCEDURE: Intercostal Nerve Block
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of Guselkumab in the Treatment of Participants With Moderate to Severe Plaque-Type Psoriasis With Randomized Withdrawal and Retreatment
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: Guselkumab 100 mg|DRUG: Placebo for guselkumab|DRUG: Adalimumab|DRUG: Placebo for adalimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Efficacy and Safety Study of CNTO1959 (Guselkumab) in the Treatment of Participants With Generalized Pustular Psoriasis or Erythrodermic Psoriasis
Status: COMPLETED
Conditions: Pustular Psoriasis
Interventions: DRUG: Guselkumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimising Cancer Therapy And Identifying Causes of Pneumonitis USing Artificial Intelligence (COVID-19)
Status: COMPLETED
Conditions: Lung Cancer|Covid19|Pneumonitis
Interventions: DIAGNOSTIC_TEST: Machine Learning Classification of parenchymal lung change cause|DIAGNOSTIC_TEST: Machine Learning Classification of recurrence and non-recurrence
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Aerobic Exercise Versus Resistance Exercise on Bone Density in Postmenopausal Diabetic Women
Status: ACTIVE_NOT_RECRUITING
Conditions: Osteoporosis
Interventions: PROCEDURE: aerobic exercise|PROCEDURE: resistance exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Vaccination With Autologous Dendritic Cells Loaded With Autologous Tumour Homogenate After Curative Resection for Stage IV Colorectal Cancer.
Status: UNKNOWN
Conditions: Stage IV Colorectal Cancer|Curative Resection
Interventions: BIOLOGICAL: autologous dendritic cells loaded with autologous tumour homogenate|DRUG: IL2
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial to Evaluate the Effect of C21 on Endothelial Dysfunction in Subjects With Type 2 Diabetes
Status: COMPLETED
Conditions: Type2diabetes|Endothelial Dysfunction
Interventions: DRUG: C21
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of Safety and Biomarker Efficacy of TS23 in Healthy Volunteer
Status: UNKNOWN
Conditions: Thrombosis|Cerebral Ischemia|Venous Thrombosis|Pulmonary Embolism|Myocardial Infarction
Interventions: BIOLOGICAL: TS23
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Clinical Efficacy and Safety of Tobradex® ST Compared to Azasite® in the Treatment of Subjects With Moderate to Severe Chronic Blepharitis
Status: COMPLETED
Conditions: Blepharitis
Interventions: DRUG: Tobradex ST|DRUG: Azasite
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Multiple Ascending Dose Study of R1507 in Children and Adolescents With Advanced Solid Tumors.
Status: COMPLETED
Conditions: Neoplasms
Interventions: DRUG: RG1507|DRUG: RG1507|DRUG: RG1507
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antiperspirant in the Treatment of Residual Limp Hyperhidrosis for Prosthetic Users
Status: COMPLETED
Conditions: Hyperhidrosis|Residual Limbs
Interventions: OTHER: Topical antiperspirant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acute Beetroot Juice Supplementation in Amateur Climbers
Status: COMPLETED
Conditions: Dietary Supplement|Sport Performance
Interventions: DIETARY_SUPPLEMENT: Beetroot Juice (BJ) acute supplementation|DIETARY_SUPPLEMENT: Placebo Juice (PLA) acute supplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Pantoprazole for Sleepiness Associated With Acid Reflux and Sleep Apnea
Status: COMPLETED
Conditions: Acid Reflux Disease|Obstructive Sleep Apnea
Interventions: DRUG: Pantoprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Assess the Safety, Tolerability, PK and Anti-tumor Efficacy of DZD2269 in Patients With MCRPC
Status: TERMINATED
Conditions: Metastatic Castration Resistant Prostate Cancer
Interventions: DRUG: DZD2269
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Skin and Systemic Biomarkers In Patients With Active Cutaneous Lupus Erythematosus And In Healthy Volunteers
Status: COMPLETED
Conditions: Lupus Erythematosus, Cutaneous|Lupus Erythematosus, Systemic|Lupus Erythematosus, Discoid|Healthy
Interventions: PROCEDURE: Skin biopsy|PROCEDURE: Blood collection|PROCEDURE: Urine collection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Clinical Trial of the Vessel Sealing System (LigaSure) in Azygoportal Disconnection and Splenectomy in Patients With Portal Hypertension
Status: COMPLETED
Conditions: Liver Cirrhosis
Interventions: DEVICE: Vessel sealing system LigaSure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Research Study of Nutritional Methods to Reduce Body Fat Percentages in Overweight and Obese Populations
Status: UNKNOWN
Conditions: Obesity
Interventions: PROCEDURE: Non-Personalized Meal Planning|PROCEDURE: Personalized Meal Planning and Dietetic Consultation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: FFS - Far Field Sensing Test Study in Cardiac Dual Chamber Pacemakers
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DEVICE: Individualized Programming of PVAB|DEVICE: Nominal PVAB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Acupuncture, Dry Needle and Botox Injection in Management of Patient With Myofascial Pain Dysfunction Syndrome
Status: RECRUITING
Conditions: Myofascial Trigger Point Pain|Myofascial Pain Syndrome
Interventions: DEVICE: Acupuncture needle|DEVICE: Dry needle|DRUG: Botox Injectable Product
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial to Determine the Safety and Efficacy of Influenza Virus Vaccine, Trivalent, Types A & B, Live, Cold-Adapted (CAIV-T) in Healthy Children
Status: COMPLETED
Conditions: Healthy
Interventions: BIOLOGICAL: CAIV-T, Liquid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Manual Therapy on the Improvement of Functional Disability in Patients With Chronic Non Specific Low Back Pain
Status: COMPLETED
Conditions: Back Pain Lower Back Chronic
Interventions: PROCEDURE: Manual therapy and active exercises|PROCEDURE: Detuned ultrasound and active exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: EuroNeut41: Safety & Immunogenicity of Immunisations With HIV Vaccine
Status: COMPLETED
Conditions: HIV
Interventions: BIOLOGICAL: EN41-FPA2 HIV vaccine|BIOLOGICAL: EN41-FPA2 HIV vaccine|BIOLOGICAL: EN41-FPA2 HIV vaccine|BIOLOGICAL: EN41-FPA2 HIV vaccine|BIOLOGICAL: Na Cl Placebo vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Endoscopic Assisted Anterior Hyaloid Peeling in Boston Type 1 Keratoprosthesis (KPro-HP-Endo)
Status: RECRUITING
Conditions: Corneal Transplantation|Glaucoma and Ocular Hypertension|Postoperative Complications|Vitrectomy|Endoscopy
Interventions: PROCEDURE: Boston keratoprosthesis type 1 and anterior hyaloid membrane peeling assisted by endoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Phenylbutyrate/Genistein Duotherapy in Delta F508-Homozygous(for Cystic Fibrosis)
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: Sodium 4-Phenylbutyrate (4PBA)|DRUG: Unconjugated Isoflavones 100 (PTI G-4660, 87% Genistein)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Blackberry-derived Polyphenols on Cardiovascular Risk in Adults
Status: COMPLETED
Conditions: Hypertension
Interventions: DIETARY_SUPPLEMENT: blackberry polyphenol enriched beverage|DIETARY_SUPPLEMENT: blackberry beverage with minimal polyphenol concentrations
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Fitmore Hip Stem PMCF Study: A Multi-centre, Non-comparative, Prospective Post-market Clinical Follow-up Study.
Status: COMPLETED
Conditions: Osteoarthritis|Avascular Necrosis|Rheumatoid Arthritis|Prosthesis Failure
Interventions: DEVICE: Fitmore Hip Stem
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: To Evaluate the Efficacy and Safety of JT-003 add-on in Patients With Type 2 Diabetes Mellitus Inadequately Controlled With Metformin and Dapagliflozin
Status: UNKNOWN
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: JT-003|DRUG: JT-003 Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An Open-label, Uncontrolled Study of ONO-7913 and ONO-4538 in Combination With Modified FOLFIRINOX Therapy, the Standard of Care, as First-line Treatment in Patients With Metastatic Pancreatic Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Pancreatic Cancer
Interventions: DRUG: ONO-7913|DRUG: ONO-4538|DRUG: Oxaliplatin|DRUG: Levofolinate|DRUG: Irinotecan|DRUG: Fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Efficacy of Musical Treadmill in PD Rehabilitation
Status: UNKNOWN
Conditions: Parkinson Disease|Gait Disorders, Neurologic|Treadmill
Interventions: BEHAVIORAL: musical treadmill|BEHAVIORAL: Traditional treadmill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Two Part Phase 1, Repeated Doses and Continuous Infusion Study With ITF2984 in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: ITF2984 (100, 2000, 3000 mcg bid)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Are Rigid Cervical Collars Necessary for Open-door Laminoplasty and Titanium Arch Plates for Cervical Myelopathy?
Status: COMPLETED
Conditions: Cervical Myelopathy
Interventions: DEVICE: Cervical collar
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Impact of Self-Monitoring Technology and Interventionist Contact on Weight Loss
Status: COMPLETED
Conditions: Overweight|Obesity
Interventions: BEHAVIORAL: Self-monitoring skills|BEHAVIORAL: Technology|BEHAVIORAL: Interventionist Contact
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Intermittent ThetaBurst Stimulation in Treatment-resistant Bipolar Depression
Status: TERMINATED
Conditions: Bipolar Depression
Interventions: DEVICE: active iTBS|DEVICE: sham iTBS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: An Expanded Access Program of Cretostimogene Grenadenorepvec for Treatment of NMIBC for Patients Unresponsive to BCG
Status: AVAILABLE
Conditions: Non-Muscle Invasive Bladder Cancer|Urothelial Carcinoma|Urologic Cancer|Bladder Cancer
Interventions: DRUG: Cretostimogene Grenadenorepvec|OTHER: n-dodecyl-B-D-maltoside
Study Type: EXPANDED_ACCESS
Clinical trial: Treatment of Advanced Hepatocellular Carcinoma
Status: UNKNOWN
Conditions: HCC
Interventions: OTHER: Basic drugs therapy of HCC|DRUG: Arginine hydrochloride|DRUG: Trimetazidine hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of LY2599506 in Patients With Type 2 Diabetes
Status: TERMINATED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Placebo|DRUG: LY2599506
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Short-term Changes on C-Reactive Protein (CRP) Levels After Non-surgical Periodontal Treatment
Status: COMPLETED
Conditions: Chronic Periodontitis|Atherosclerotic Cardiovascular Disease
Interventions: PROCEDURE: Non-surgical periodontal treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: MRI Guided Transrectal Prostate Laser Ablation for Benign Prostatic Hypertrophy (BPH)
Status: COMPLETED
Conditions: BPH|Prostate Hyperplasia|Urinary Frequency/Urgency
Interventions: DEVICE: MRI Guided Transrectal Periuretheral Transitional Zone Ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of DSC127 in Treating Subjects With Diabetic Ulcers
Status: COMPLETED
Conditions: Foot Ulcer, Diabetic|Diabetic Foot
Interventions: DRUG: NorLeu3-A(1-7) in a gel formulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Erythrocytapheresis Versus Phlebotomy as Maintenance Therapy in Hereditary Hemochromatosis (HH) Patients
Status: UNKNOWN
Conditions: Hereditary Hemochromatosis
Interventions: OTHER: Phlebotomy and erythrocytapheresis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Effect of Microchip and Density Gradient Methods in Intrauterine Insemination Cycles
Status: UNKNOWN
Conditions: Infertility Unexplained|Infertility, Male
Interventions: OTHER: MicroFluidic Sperm Sorting Chips|OTHER: Gradient-Density Centrifugation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase Ib Trial of Azacitidine, Venetoclax and Allogeneic NK Cells for Acute Myeloid Leukemia (ADVENT-AML)
Status: RECRUITING
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Azacitidine|DRUG: Venetoclax|DRUG: NK Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Insulin Efsitora Alfa (LY3209590) Compared With Insulin Degludec in Participants With Type 1 Diabetes Treated With Multiple Daily Injection Therapy
Status: COMPLETED
Conditions: Type 1 Diabetes|Diabetes
Interventions: DRUG: Insulin Efsitora Alfa|DRUG: Insulin Degludec
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Different Nasal Stent Designs With Nasoalveolar Molding Appliance
Status: NOT_YET_RECRUITING
Conditions: Cleft Lip|Cleft Lip and Palate
Interventions: DEVICE: Grape Design Nasal Stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Intermittent Pneumatic Compression (IPC) on Venous Thromboembolism Incidence in Intensive Care Unit (ICU) Patients With High Bleeding Risk
Status: COMPLETED
Conditions: High Bleeding Risk|Hemorrhage
Interventions: DEVICE: Intermittent pneumatic compression of the lower limbs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Smoking Relapse Prevention Among COPD Ex-smokers
Status: TERMINATED
Conditions: Chronic Obstructive Pulmonary Disease|Smoking Cessation
Interventions: DRUG: Varenicline|BEHAVIORAL: Behavioural support|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Emergency Versus Elective Cholecystectomy in Acute Cholecystitis in the Era of Laparoscopy.
Status: UNKNOWN
Conditions: Cholecystitis, Acute
Interventions: PROCEDURE: Laparoscopic cholecystectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Itch Control by VLY-686 in Healthy Volunteers After Intradermal Injections of Substance P
Status: COMPLETED
Conditions: Pruritus
Interventions: DRUG: VLY-686|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Strength or Power Training for Patellofemoral Pain
Status: RECRUITING
Conditions: Patellofemoral Pain
Interventions: BEHAVIORAL: Standard of Care Rehabilitation (SOC)|BEHAVIORAL: Strength Training Rehabilitation Incorporating Power Exercises (STRIPE)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acute High Intensity Interval Training and Blood Flow Restriction
Status: COMPLETED
Conditions: Activity, Motor
Interventions: OTHER: Active Comparator: HIIT Control|OTHER: Experimental: HIIT + BFR between cycling sets|OTHER: Experimental: HIIT + BFR moderate occlusion during cycling|OTHER: Experimental: HIIT + BFR high occlusion during cycling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Modified Comprehensive Behavioral Intervention for Tics (M_CBIT)
Status: COMPLETED
Conditions: Tourette Syndrome|ADHD
Interventions: BEHAVIORAL: Modified Comprehensive Behavioral Intervention for Tics|BEHAVIORAL: Comprehensive Behavioral Intervention for Tics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fitball Program Versus Task-oriented Motor Program on Improving Postural Control in Developmental Coordination Disorder
Status: COMPLETED
Conditions: Developmental Coordination Disorder
Interventions: BEHAVIORAL: Fitball exercise|BEHAVIORAL: task-oriented motor training program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Anti-Inflammatory Agent in Sinusitis
Status: COMPLETED
Conditions: Nasal Polyps
Interventions: DRUG: AZ compound|OTHER: Collection of Biological Specimens|DRUG: Intranasal corticosteroid|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Selinexor Combined With Olaparib in Relapsed/Refractory Extensive Stage Small Cell Lung Cancer
Status: RECRUITING
Conditions: Extensive-stage Small Cell Lung Cancer
Interventions: DRUG: Selinexor，Olaparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non Randomized Controlled Intervention Study Comparing Two Interventions of Nutritional Supplement on Malnutrition, Health and Mortality
Status: COMPLETED
Conditions: Malnutrition
Interventions: DIETARY_SUPPLEMENT: Ready-to-Used Supplement Food administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Lacrimal Drainage System Obstruction Associated to Radioactive Iodine Therapy for Thyroid Carcinoma
Status: UNKNOWN
Conditions: Lacrimal Apparatus Disease
Interventions: DRUG: Radioiodine therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety Distance for Endovenous Laser Ablation of the Great Saphenous Vein
Status: UNKNOWN
Conditions: Great Saphenous Vein Incompetence|Endovenous Laser Ablation
Interventions: DEVICE: EVLA with keeping of securuty distance|DEVICE: EVLA without keeping a distance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: PEG-IFN in HBV Patients With Incomplete Response to NA
Status: COMPLETED
Conditions: Chronic Hepatitis B
Interventions: DRUG: Nucleos(t)ide analogue treatment with a peginterferon add-on strategy|DRUG: Nucleos(t)ide analogue treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improving Functional Outcomes in Patients With Unilateral Vocal Cord Paralysis: Assessment of Adaptation Using Functional Magnetic Resonance Imaging
Status: COMPLETED
Conditions: Intrathoracic Malignancies|Unilateral Vocal Cord Paralysis
Interventions: OTHER: voice evaluation and fMRI|OTHER: undergo voice evaluation and fMRI prior
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy Study of FES Controlled by Electromyographic Signal for the Treatment of Upper Limb in Post-stroke Patients
Status: COMPLETED
Conditions: Stroke
Interventions: DEVICE: MeCFES-assisted task-oriented upper limb rehabilitation|OTHER: Usual Care task-oriented upper limb rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Magnetic Resonance Elastography in Glioma: Exploring Tumor Stiffness and Adhesion
Status: RECRUITING
Conditions: Glioma
Interventions: DIAGNOSTIC_TEST: Magnetic Resonance Elastography|PROCEDURE: Assessment and Recording
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effect and Safety of Omitting Preoperative Alpha-adrenergic Blockade for Normotensive Pheochromocytoma
Status: RECRUITING
Conditions: Pheochromocytoma|Paraganglioma|Adrenalectomy; Status|Adrenergics Causing Adverse Effects in Therapeutic Use
Interventions: DRUG: Phenoxybenzamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Hydroxychloroquine for the Treatment of Mild COVID-19 Disease
Status: TERMINATED
Conditions: COVID-19
Interventions: DRUG: Hydroxychloroquine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Comparison of Albuterol Spiromax® and ProAir® Hydrofluoroalkane (HFA) in Pediatric Patients
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Albuterol Spiromax|DRUG: ProAir HFA|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Molecular Imaging Probes to Inform Heterogeneity in Idiopathic Pulmonary Fibrosis
Status: RECRUITING
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: DRUG: PET/CT using PET ligands [F-18]FDG and [F-18]DPA-714
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of ENMD-2076 in Patients With Advanced/Metastatic Soft Tissue Sarcoma
Status: COMPLETED
Conditions: Advanced|Metastatic|Soft Tissue Sarcoma
Interventions: DRUG: ENMD-2076
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HEPAR Primary: Holmium-166-radioembolization in Hepatocellular Carcinoma Patients
Status: COMPLETED
Conditions: Hepatocellular Carcinoma|Hepatocellular Carcinoma Non-resectable
Interventions: DEVICE: Holmium-166 radioembolization
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Infant Sleep and Exposure to Mixture of Chemical Environmental Pollutants
Status: RECRUITING
Conditions: Newborn|Chemical Pollutants Exposure|Sleep
Interventions: DEVICE: 7-day actimetry sleep recording|OTHER: Determination of environmental pollutants in breast milk|OTHER: Measurements of environmental pollutants in indoor air deposited on the bracelet worn by the child|OTHER: Continuous recording of the child&#39;s temperature for 7 days|OTHER: Use of a sleep diary for 7 days|OTHER: Parental questionnaire of environmental exposure
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: HEM-iSMART-B: Dasatinib + Venetoclax + Dexamethasone + Cyclophosphamide and Cytarabine in Pediatric Patients With Relapsed or Refractory Hematological Malignancies
Status: NOT_YET_RECRUITING
Conditions: Acute Lymphoblastic Leukemia|Lymphoblastic Lymphoma (Precursor B-Lymphoblastic Lymphoma/Leukaemia) Recurrent|Lymphoblastic Lymphoma (Precursor T-Lymphoblastic Lymphoma/Leukaemia) Recurrent|Lymphoblastic Lymphoma (Precursor B-Lymphoblastic Lymphoma/Leukaemia) Refractory|Lymphoblastic Lymphoma (Precursor T-Lymphoblastic Lymphoma/Leukaemia) Refractory
Interventions: DRUG: Dasatinib|DRUG: Venetoclax|DRUG: Dexamethasone|DRUG: Cyclophosphamide|DRUG: Cytarabine|DRUG: intrathecal chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Train Your Brain and Exercise Your Heart? Advancing the Treatment for Attention Deficit Hyperactivity Disorder (ADHD)
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder (ADHD)
Interventions: OTHER: Neurofeedback|BEHAVIORAL: Exercise|DRUG: methylphenidate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multimodal Ocular Imaging in Neurodegeneration
Status: COMPLETED
Conditions: Alzheimer Disease|Alzheimer Dementia|Frontotemporal Dementia
Interventions: DEVICE: Spectral-Domain Optical Coherence Tomography (SD-OCT)|DEVICE: Magnetic Resonance Imaging (MRI)|DEVICE: Positron Emission Tomography (PET)|DIAGNOSTIC_TEST: Comprehensive Ophthalmic Examination|DEVICE: Fundus Photography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Antiretroviral Localization in Gut-Associated Lymphoid Tissue and Lower Female Genital Tract Tissue of HIV+ Subjects
Status: TERMINATED
Conditions: HIV
Interventions: PROCEDURE: Blood plasma collection|PROCEDURE: Cervical and Vaginal Biopsy|PROCEDURE: Colonoscopy with Ileal and Rectal Biopsy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Brain and Coordination Changes Induced By Robotics and FES Treatment Following Stroke
Status: COMPLETED
Conditions: Cerebral Stroke|Cerebrovascular Accident|Stroke
Interventions: DEVICE: Robotics training for shoulder elbow.|DEVICE: Surface Functional Neuromuscular Stimulation|OTHER: whole arm motor learning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT