pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Orodental Hygiene in Children With Special Needs
Status: RECRUITING
Conditions: Oral Hygiene
Interventions: DIAGNOSTIC_TEST: Oral Examination|DIAGNOSTIC_TEST: PUFA index|DIAGNOSTIC_TEST: Plaque index|DIAGNOSTIC_TEST: Streptococcus mutans screening|BEHAVIORAL: Education
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Parp Inhibitor in Advanced Non-Small Cell Lung Cancer (PIN)
Status: UNKNOWN
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: Olaparib|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of the Product "CHF 1535" Versus Beclomethasone (BDP) and Free Combo in Asthmatic Children
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: CHF 1535|DRUG: Beclomethasone (BDP)|DRUG: Beclomethasone (BDP) + Formoterol Fumarate (FF)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the BIOPIN 6 Naltrexone Implant in Healthy Adults
Status: ENROLLING_BY_INVITATION
Conditions: Opioid Use Disorder
Interventions: COMBINATION_PRODUCT: BIOPIN-6 Active Implant with Naltrexone|DEVICE: BIOPIN-6 Placebo Implant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Improving Mothers for a Better PrenAtal Care Trial Barcelona
Status: COMPLETED
Conditions: Intrauterine Growth Restriction|Fetal Growth Retardation
Interventions: BEHAVIORAL: Mediterranean diet|BEHAVIORAL: Mindfulness
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: A Study to Determine Effective and Tolerable Titration Scheme for OROS-Methylphenidate in Children With Attention-deficit Hyperactivity Disorder
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: DRUG: OROS-methylphenidate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Skin Sensitivity Acupuncture and Kinesiotherapy on Breast Cancer Patients Subject to Chemotherapy With Taxans
Status: COMPLETED
Conditions: Chemotherapy Effect
Interventions: OTHER: Stiper|OTHER: Acupuncture|OTHER: Exercise|OTHER: Follow Up|OTHER: Observation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Clinical and Histological Evaluation of Hesperidin as a Direct Pulp Capping Material
Status: COMPLETED
Conditions: Pulp Exposure, Dental|Dental Pulp Capping
Interventions: OTHER: Hesperidin|OTHER: Mineral Trioxide Aggregate (MTA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Dulaglutide in Japanese Participants With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: LY2189265|DRUG: Insulin glargine|DRUG: Sulfonylureas (SU)|DRUG: Biguanide (BG)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nitrate Supplementation and Exercise Tolerance in Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DIETARY_SUPPLEMENT: Super Beets|OTHER: Super Beets Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: S0635: Erlotinib and Bevacizumab in Stage IIIB and IV Bronchioloalveolar Carcinoma
Status: COMPLETED
Conditions: Lung Cancer
Interventions: BIOLOGICAL: bevacizumab|DRUG: erlotinib hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating the Efficacy and Safety of Topical Diclofenac Spray in Osteoarthritis of the Knee: Trial II
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DRUG: TDS-943 (topical diclofenac sodium 4% spray)|DRUG: celecoxib|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Evaluating an In-home Multicomponent Program to Manage Concerns About Falling in Frail Community Dwelling Older People
Status: COMPLETED
Conditions: Concerns About Falling|Aged
Interventions: BEHAVIORAL: an in-home cognitive behavioral program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of Cinepazide Maleate Injection in the Treatment of Acute Ischemic Stroke
Status: COMPLETED
Conditions: Stroke, Ischemic
Interventions: DRUG: Cinepazide Maleate|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Beneficial Effects of Probiotics on Improvement of Gut Dysbiosis and Ascending Cholangitis in Patients Received Pancreaticoduodenectomy
Status: COMPLETED
Conditions: Precancerous Lesions
Interventions: DIETARY_SUPPLEMENT: Yugart
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stress Reduction in the Prevention of Left Ventricular Hypertrophy
Status: COMPLETED
Conditions: Left Ventricular Hypertrophy|High Blood Pressure
Interventions: BEHAVIORAL: meditation|BEHAVIORAL: Health education control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of a 4-week Fun Fast Interval Training (FFIT) Activity Programme on Physical Fitness and Quality of Life in Adolescent School Pupils
Status: COMPLETED
Conditions: High-intensity Interval Training
Interventions: OTHER: High-intensity interval exercise training
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Chemerin, Fetuin-A, IL-34 and IL-13 Levels in Diabetic Periodontitis Patients
Status: COMPLETED
Conditions: Periodontitis|Diabetes Mellitus, Type 2
Interventions: PROCEDURE: Non-Surgical Periodontal Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Stereotype Threat on Impulsivity and Its Relation to Alcohol Use in African Americans: An fMRI Study
Status: RECRUITING
Conditions: Alcohol Drinking
Interventions: BEHAVIORAL: Task-based behavioral intervention|BEHAVIORAL: Task-based behavioral intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Lifeline-NET (Narrative Exposure Therapy): A Short-term Treatment for Traumatized Refugees and Asylum Seekers
Status: COMPLETED
Conditions: Trauma Treatment|Lifeline NET|Modification of Narrative Exposure Therapy
Interventions: BEHAVIORAL: Lifeline NET
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acupoint Stimulation Improves Cognition Under Hypoxia
Status: NOT_YET_RECRUITING
Conditions: Cognition
Interventions: OTHER: transcutaneous electrical acupoint stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Impact of Heartfulness Self-Care Program on Anxiety, Satisfaction With Life, and Loneliness Levels in Students and Staff in High Schools.
Status: COMPLETED
Conditions: Anxiety|Satisfaction With Life|Loneliness
Interventions: BEHAVIORAL: Self-Care Program through Heartfulness
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effectiveness of Physical Therapy Program to Treat Rotator Cuff Disorders Among Nursing Professionals
Status: COMPLETED
Conditions: Shoulder Impingement Syndrome|Quality of Life|Satisfaction
Interventions: OTHER: Control, no Proprioception|OTHER: Experimental, Proprioceptive exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Anthropometrics Data and of Physical Activity Level in Closed kineTic Chain Upper Extremity Stability Test
Status: COMPLETED
Conditions: Shoulder Pain
Interventions: DIAGNOSTIC_TEST: Closed Kinetic Chain Upper Extremity Stability Test
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Multiple-dose Regimen Study to Assess Effect of 12 Months of Secukinumab Treatment on Skin Response and Biomarkers in Psoriasis Patients
Status: COMPLETED
Conditions: Psoriasis, Plaque-type Psoriasis
Interventions: DRUG: secukinumab|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Valsartan 160mg and Rosuvastatin 20mg in Patients With Hypertension and Hyperlipidemia
Status: COMPLETED
Conditions: Hypertension,|Hyperlipidemia
Interventions: DRUG: Valsartan 160mg|DRUG: Rosuvastatin 20mg|DRUG: Valsartan 160mg placebo|DRUG: Rosuvastatin 20mg placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Liraglutide on Body Weight in Overweight or Obese Subjects With Type 2 Diabetes: SCALE™ - Diabetes
Status: COMPLETED
Conditions: Metabolism and Nutrition Disorder|Obesity
Interventions: DRUG: liraglutide|DRUG: liraglutide|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness and Tolerance of Cicaplast Baume B5 After Superficial CO2 Laser Resurfacing
Status: COMPLETED
Conditions: Wound Heal
Interventions: OTHER: superficial CO2 laser resurfacing|OTHER: Laser untreated side
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Effectiveness of Oral Management Strategies on Improving Oral Frailty and Oral Bacteria
Status: COMPLETED
Conditions: Oral Hygiene|Pneumonia, Bacterial
Interventions: PROCEDURE: Group with oral management|PROCEDURE: Group with oral care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Single-dose, Open-label, Pharmacokinetic Study of Belapectin (GR-MD-02) in Subjects With Normal Hepatic Function and Subjects With Varying Degrees of Hepatic Impairment
Status: COMPLETED
Conditions: Hepatic Impairment
Interventions: DRUG: belapectin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Resveratrol In Chronic Obstructive Pulmonary Disease (COPD) Patients (CARMENS-trial)
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DIETARY_SUPPLEMENT: Resveratrol|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Fatty Liver Imaging Project
Status: COMPLETED
Conditions: Determine the Number of Anatomical Sites at Which Successful Thermoacoustic Fat Measurements Can be Made From Five Acquisitions Using the FLIP ITA Device|Determine the Correlation of Fat Measures Obtained by the FLIP Device and Those Obtained From Quantitative MRI|Provide Insight Into the Sensitivity of Thermoacoustic Liver Fat Assessment With the Aim of Detecting Fat Content in Liver at 15% or Less, by Volume
Interventions: DEVICE: Liver Imaging
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of a Genistein Concentrated Polysaccharide (GCP) for Prostate Cancer on Active Surveillance.
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: Placebo|DRUG: GCP - Genistein Combined Polysaccharide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Emotional Cognition: Establishing Constructs and Neural-Behavioral Mechanisms in Older Adults With Depression
Status: RECRUITING
Conditions: Major Depressive Disorder (MDD)|Healthy Adult Volunteer
Interventions: BEHAVIORAL: Hot Cognitive Task|BEHAVIORAL: Cold cognitive tasks|OTHER: Structural magnetic resonance imaging (sMRI)|OTHER: Magnetoencephalography imaging (MEG)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Returning Genetic Results on Arsenic Susceptibility
Status: COMPLETED
Conditions: Arsenic Exposure
Interventions: OTHER: Personal information on genetic susceptibility to arsenic toxicity|OTHER: standard information on arsenic exposure reduction
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Exploring the Benefit of Neuromodulation in Treating Chemo-induced Peripheral Neuropathy Using Peripheral Neuropathy Markers (Meissner's Corpuscles and Epidermal Nerve Fiber Density) and Sensory Testing (Quantitative Sensory and Gait Testing): A Single Center Feasibility Study
Status: RECRUITING
Conditions: Neuropathy;Peripheral
Interventions: DEVICE: Abbott® DRG / Abbott®/Medtronic® SCS|OTHER: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chlorhexidine and Garlic Extract as Potential Topical Virucidal Therapeutic Agents of Non-Genital Warts
Status: NOT_YET_RECRUITING
Conditions: Non-Genital Warts
Interventions: DRUG: garlic extract (15%) solution|DRUG: topical chlorhexidine (2%) solution|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Thumb Hemi-Arthroplasty With Natural Kinematics (THANKS) Trial
Status: COMPLETED
Conditions: Osteoarthritis Thumb Base Joint
Interventions: DEVICE: InDx Implant for the carpometacarpal joint
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bright Light Therapy for Depression Symptoms in Adults With Cystic Fibrosis (CF) and COPD
Status: TERMINATED
Conditions: Cystic Fibrosis|Depressive Symptoms|Chronic Obstructive Pulmonary Disease
Interventions: DEVICE: Bright Light Therapy (BLT) Lamp
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: FreeStyle Libre 2 Discharge Trial
Status: RECRUITING
Conditions: Diabetes Mellitus, Type 2|Hypoglycemia
Interventions: DEVICE: FreeStyle Libre 2 CGM|DEVICE: FreeStyle Libre Pro blinded CGM|DEVICE: FreeStyle Precision Neo blood glucose meter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The (Cost-) Effectiveness of Paediatric Laparoscopic Hernia Repair Compared to Open Hernia Repair
Status: RECRUITING
Conditions: Inguinal Hernia
Interventions: PROCEDURE: Percutaneous Inguinal Ring Suturing (PIRS) technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Measuring Thoracic Impedance in Hemodialysis Patients With the u-Cor Monitoring System
Status: COMPLETED
Conditions: Fluid Retention Tissue
Interventions: DEVICE: u-Cor System|DEVICE: ZOE Fluid Status Monitor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Cardiovascular and Renal Microvascular Outcome Study With Linagliptin in Patients With Type 2 Diabetes Mellitus (CARMELINA)
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Placebo|DRUG: Linagliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Differential Adrenoreceptor Mediated Tachyphylaxis and Upregulation
Status: COMPLETED
Conditions: Allergic Rhinitis|Tachyphylaxis|Rhinitis Medicamentosa
Interventions: DRUG: Oxymetazoline 0.05% w/v|DRUG: Fluticasone propionate 50 micrograms per actuation|DRUG: Prazosin hydrochloride|DRUG: Placebo to Prazosin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Thorough QT/QTc Study of Multiple Oral Doses of NOMAC-E2 (Org 10486 0 + Org 2317) in Healthy Women (Study 292011)(P05802)
Status: COMPLETED
Conditions: Contraception
Interventions: DRUG: Moxifloxacin|DRUG: NOMAC-E2 (Org 10486-0 + Org 2317)|DRUG: Moxifloxacin placebo|DRUG: NOMAC-E2 placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Effect of Soy Supplementation on Cellular Markers in Normal and Cancerous Breast Tissue: A Randomized Placebo Controlled Study
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DIETARY_SUPPLEMENT: Soy|DIETARY_SUPPLEMENT: Milk
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Study of Pulmonary MRI for the Diagnosis of Bronchiolitis Obliterans Syndrome After Allogeneic Stem Cell Transplantation
Status: RECRUITING
Conditions: Bronchiolitis Obliterans
Interventions: DEVICE: lung MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Vein-Coronary Atherosclerosis And Rosiglitazone After Bypass Surgery: The VICTORY Trial
Status: COMPLETED
Conditions: Diabetes|Coronary Artery Bypass Grafting
Interventions: DRUG: Rosiglitazone or placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Studying a Tumor Marker for Testicular Cancer, Skin Cancer, Small Intestine Cancer, and Pancreatic Cancer
Status: TERMINATED
Conditions: Non-melanomatous Skin Cancer|Pancreatic Cancer|Small Intestine Cancer|Testicular Germ Cell Tumor
Interventions: GENETIC: in situ hybridization|GENETIC: protein expression analysis|OTHER: immunologic technique
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: High-Flow Oxygen for Dyspnea in Hospitalized Cancer Patients
Status: COMPLETED
Conditions: Cancer
Interventions: OTHER: High-flow Oxygen|OTHER: Low-flow Oxygen|OTHER: High-flow Air|OTHER: Low-flow Air
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Covid-19 and Influenza Oral Vaccine Study
Status: RECRUITING
Conditions: covid19 Infection|Influenza, Human
Interventions: BIOLOGICAL: Covid-19 vaccine|BIOLOGICAL: Influenza vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Volume Stable Collagen Matrix in RT2 Gingival Recession Compared to Connective Tissue Graft
Status: RECRUITING
Conditions: Gingival Recession
Interventions: PROCEDURE: Root coverage procedure will be done with VCMX|PROCEDURE: Root coverage procedure will be done with CTG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of LQT-1213 on QTc-induced Prolongation in Healthy Adult Subjects (Part1) and on Congenital Long QT in Patients Diagnosed With Type 1, 2 or 3 Long QT Syndrome (Part 2).
Status: RECRUITING
Conditions: Long QT Syndrome
Interventions: DRUG: LQT-1213|DRUG: Placebo|DRUG: Dofetilide 250 μg Cap
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: ACT-GLOBAL Adaptive Platform Trial for Stroke
Status: NOT_YET_RECRUITING
Conditions: Stroke
Interventions: DRUG: Standard-dose intravenous tenecteplase|DRUG: Low-dose intravenous tenecteplase|OTHER: No intravenous tenecteplase|OTHER: Conservative Blood Pressure Control|OTHER: Moderate Blood Pressure Control|OTHER: Intensive Blood Pressure Control|OTHER: Placebo|DRUG: NoNO-42
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trans Abdominis Plane (TAP) Block in Patients With Cesarean Section
Status: UNKNOWN
Conditions: Analgesia|Cesarean Section Complications
Interventions: PROCEDURE: Transverse abdominis plane (TAP) block|DRUG: Bupivacain|DRUG: Tramadol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Role of Pegylated Interferon in Combination With DAAs to Cure Hepatitis C As Soon As Possible - Hepatitis C [ASAP-C]
Status: COMPLETED
Conditions: Hepatitis C, Chronic
Interventions: DRUG: Sofosbuvir|DRUG: Daclatasvir|DRUG: Pegylated Interferon alfa-2a
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Consuming a Combination of Probiotic Strains and a Combination of Plant Extracts and a Probiotic Strain on the Production and Nutritional Composition of Breast Milk
Status: UNKNOWN
Conditions: Breast Milk Expression
Interventions: DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: Prob-milk|DIETARY_SUPPLEMENT: Voluntas-Prob
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Prevention of Chronic Lung Disease (CLD) in Preterm Infants
Status: UNKNOWN
Conditions: Respiratory Distress Syndrome|Chronic Lung Disease of Prematurity
Interventions: DRUG: budesonide|DRUG: surfactant and air (placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Is PNF Application Effective on Temporomandibular Dysfunction
Status: ENROLLING_BY_INVITATION
Conditions: TMD|TMJ Disorder|Pain
Interventions: OTHER: Rocabado's 6x6 Exercises|OTHER: PNF Exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prevention of Enamel Demineralization Using CPP-ACP-NaF Varnish
Status: COMPLETED
Conditions: Demineralization
Interventions: DEVICE: CPP-ACP-NaF varnish
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Immune Response and Safety of GSK Biologicals' HPV-16/18 L1 VLP AS04 Vaccine/Cervarix TM Vaccine in Healthy Females Aged 15-25 Years
Status: COMPLETED
Conditions: Infections, Papillomavirus
Interventions: BIOLOGICAL: HPV-16/18 VLP/AS04 vaccine (Cervarix TM)|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Risky Decision Making in Methamphetamine Users: The Role of Opioid Blockade
Status: COMPLETED
Conditions: Methamphetamine Abuse|HIV
Interventions: DRUG: Extended release naltrexone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Recombinant Interleukin-15 in Combination With Checkpoint Inhibitors Nivolumab and Ipilimumab in People With Refractory Cancers
Status: RECRUITING
Conditions: Metastatic Solid Tumors|Treatment-Refractory Cancers
Interventions: DRUG: rhIL-15|DRUG: Ipilimumab|DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Coenzyme q 10 and Fertility Outcome in Women With Clomiphene Resistant PCOS
Status: COMPLETED
Conditions: Coenzyme q10
Interventions: DRUG: Coenzyme Q10|DRUG: clomiphene citrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Strong African American Families STEPS Project
Status: COMPLETED
Conditions: Adolescent Alcohol Use
Interventions: BEHAVIORAL: Strong African American Families Program|BEHAVIORAL: Strong African American Families--Teen Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Efficacy and Safety of Two Secukinumab Dose Regimens in Subjects With Moderate to Severe Hidradenitis Suppurativa (HS)
Status: COMPLETED
Conditions: Hidradenitis Suppurativa
Interventions: DRUG: Secukinumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: To Evaluate the Safety and Efficacy of Trexima in the Acute Treatment of Migraine Headaches
Status: COMPLETED
Conditions: Migraine Headaches
Interventions: DRUG: sumatriptan|DRUG: naproxen sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Placebo-Controlled Study of Clonidine for Fecal Incontinence.
Status: COMPLETED
Conditions: Fecal Incontinence
Interventions: DRUG: Clonidine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CPAP Therapy Through a Helmet or a Full Face Mask in Patients With Acute Hypoxemic Respiratory Failure: Cross-over Study
Status: COMPLETED
Conditions: Pneumonia, Bacterial|Respiratory Failure|COVID-19 Pneumonia
Interventions: DIAGNOSTIC_TEST: Arterial blood gases|DIAGNOSTIC_TEST: Respiratory rate (RR)|DIAGNOSTIC_TEST: Pulseoximeter|DIAGNOSTIC_TEST: Assessment of accessory respiratory muscles work|DIAGNOSTIC_TEST: Esophageal pressure measurement|DIAGNOSTIC_TEST: Discomfort Visual Analog Scale (VAS)|DIAGNOSTIC_TEST: Noninvasive blood pressure|DIAGNOSTIC_TEST: Heart rate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Carbetocin vs. Oxytocin for Prevention of Postpartum Bleeding in Patients With Severe Preeclampsia
Status: UNKNOWN
Conditions: Severe Preeclampsia|Postpartum Hemorrhage
Interventions: DRUG: Carbetocin|DRUG: Oxytocin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DRUG: carboplatin|DRUG: paclitaxel|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study on Prognosis of Patients With Severe NPDR Undergoing Vitrectomy
Status: NOT_YET_RECRUITING
Conditions: Non Proliferative Diabetic Retinopathy(NPDR)
Interventions: PROCEDURE: pars plana vitrectomy(PPV)|PROCEDURE: Pars plana vitrectomy(PPV) +Panretinal photocoagulation(PRP)|PROCEDURE: Panretinal photocoagulation(PRP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Left Atrial FLUTter: a Comparison of Ablation Guided by High-density MApping and Empirical LINEar Ablation.
Status: RECRUITING
Conditions: Arrhythmias, Cardiac
Interventions: OTHER: Radiofrecuency ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EYE-TRAC Advance: Technology Verification (ETA-TV) Cohort 2
Status: TERMINATED
Conditions: Eye-tracking
Interventions: DEVICE: EYE-SYNC eye-tracking|OTHER: SCAT-3 subtests|OTHER: DEM|OTHER: Simple Reaction Time subtest of ANAM-SRT|OTHER: Level of Alertnesss
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Mindfulness Based Cognitive Training in Children and Adolescents With ADHD
Status: COMPLETED
Conditions: ADHD
Interventions: BEHAVIORAL: Mindfulness based cognitive training|OTHER: Control exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial to Evaluate the Effect of Fimarsartan on Pharmacodynamics, Pharmacokinetics, and the Safety of Warfarin in Healthy Male Volunteers
Status: COMPLETED
Conditions: Essential Hypertension
Interventions: DRUG: fimasartan, warfarin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: 'Smart Reminder': a Feasibility Pilot Study on the Effects of a Wearable Device Treatment
Status: COMPLETED
Conditions: Stroke
Interventions: DEVICE: Wearable device -'Smart Reminder'|OTHER: Conventional therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SCALE-UP Utah: Community-Academic Partnership to Address COVID-19 Testing Among Utah Community Health Centers
Status: COMPLETED
Conditions: Covid19
Interventions: BEHAVIORAL: Text-Messaging (TM)|BEHAVIORAL: Patient Navigation (PN)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SCREENING
Clinical trial: Perioperative Evaluation of MMP-9-TIMP-1 System in Vascular Surgery Regarding Ischemic-reperfusion Injury
Status: COMPLETED
Conditions: Ischemia Reperfusion Injury
Interventions: PROCEDURE: aorto-bifemoral bypass and aorta stentgraft
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Using a Text-message System to Engage Depressed Adolescents in Cognitive-behavioral Therapy Homework
Status: COMPLETED
Conditions: Major Depressive Disorder|Cognitive Behavior Therapy|Text Messaging
Interventions: BEHAVIORAL: Paper and pen homework|DEVICE: Text message system homework.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Observational Study of Peginterferon Alfa-2a (PEGASYS®) in Patients With HBeAg Positive or HBeAg Negative Chronic Hepatitis B
Status: COMPLETED
Conditions: Hepatitis B, Chronic
Interventions: BIOLOGICAL: Peginterferon alfa-2a
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Aerobic Training Versus Behavioral Intervention to Increase Physical Activity in Patients With Asthma
Status: RECRUITING
Conditions: Asthma
Interventions: BEHAVIORAL: Behavioral Intervention to Increase Physical Activity|OTHER: Aerobic Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Methods to Improve Expiratory Cough Flow and Lung Volume in Children With NMDs
Status: COMPLETED
Conditions: Neuromuscular Diseases
Interventions: DEVICE: Non-invasive bipap ventilator|DEVICE: Mechanical insufflator-exsufflator|DEVICE: High frequency percussive oscillator
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Analyzing Female Trauma Exposed Responses to a Medication
Status: COMPLETED
Conditions: Stress Disorders, Post-traumatic
Interventions: DRUG: GSK561679|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lyophilized IMVAMUNE® (1x10^8 TCID50) Versus Liquid IMVAMUNE® (1x10^8 TCID50) Administered Subcutaneously and a Lower Dose Liquid IMVAMUNE® (2x10^7 TCID50) Administered Intradermally
Status: COMPLETED
Conditions: Smallpox
Interventions: BIOLOGICAL: MVA Smallpox Vaccine|BIOLOGICAL: MVA Smallpox Vaccine|BIOLOGICAL: MVA Smallpox Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Mechanical Device for the Relief of Hot Flashes
Status: COMPLETED
Conditions: Hot Flashes
Interventions: DEVICE: Menopod|DEVICE: Inactive device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of DLBS3233 in Subjects With New Onset of Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Type-2-diabetes Mellitus|New Onset
Interventions: DRUG: Placebo of DLBS3233|DRUG: DLBS3233|OTHER: Lifestyle modification
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Fish Oil and Resistance Training on Muscle Mass and Function
Status: SUSPENDED
Conditions: Fat-free Masss|Muscle Strength|Neuromuscular Function
Interventions: DIETARY_SUPPLEMENT: Fish oil|DIETARY_SUPPLEMENT: Coconut oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Cryoablation for Phantom Limb Pain
Status: COMPLETED
Conditions: Phantom Limb Syndrome
Interventions: PROCEDURE: Cryoablation|DEVICE: 17g Galil Medical Ice Sphere cryoablation needle
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Metastatic Castrate-Resistant Prostate Cancer Subjects Treated With PROVENGE® + One Infusion of Sipuleucel-T
Status: NOT_YET_RECRUITING
Conditions: Metastatic Castration-Resistant Prostate Cancer (mCRPC)
Interventions: DRUG: Sipuleucel-T Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Tolfenamic Acid in Individuals With PSP at 12-Weeks
Status: UNKNOWN
Conditions: Progressive Supranuclear Palsy
Interventions: DRUG: Tolfenamic Acid|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Liver Resection Versus Radio-chemotherapy-Transplantation for Hilar Cholangiocarcinoma
Status: UNKNOWN
Conditions: Cholangiocarcinoma
Interventions: PROCEDURE: CAPECITABINE-Radiotherapy -Liver Transplantation|PROCEDURE: RESECTION
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Evaluate the Efficacy and Safety of an Immunomodulatory Therapy for the Treatment of Patients With Moderate to Severe COVID-19 Infection
Status: COMPLETED
Conditions: COVID-19 Infection
Interventions: DRUG: metenkefalin + tridecactide|DRUG: The standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improving Aspirin Use Among Adults at Risk for Cardiovascular Disease (CVD)
Status: COMPLETED
Conditions: Cardiovascular Disease
Interventions: BEHAVIORAL: Pre-visit Summary|BEHAVIORAL: Clinical Decision Sharing Tool
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Effects of Ferric Derisomaltose in Patients With Acute Heart Failure and Iron Deficiency on Exercise Capacity and Quality of Life(COREVIVE-HFrEF)
Status: RECRUITING
Conditions: Heart Failure With Reduced Ejection Fraction|Iron Deficiency|Acute Heart Failure
Interventions: DRUG: Ferric derisomaltose|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating Bazedoxifene/Conjugated Estrogen Combinations in Vasomotor Symptoms Associated With Menopause
Status: COMPLETED
Conditions: Vaginal Atrophy
Interventions: DRUG: Bazedoxifene/Conjugated Estrogen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety and Pharmacokinetics/Pharmacodynamics of SHR3824 in Type 2 Diabetes Patients With Renal Insufficient
Status: UNKNOWN
Conditions: Renal Insufficiency,Type 2 Diabetes
Interventions: DRUG: SHR3824
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Women's Healthy Lifestyle Project: Cardiovascular Risk Factors and Menopause
Status: COMPLETED
Conditions: Cardiovascular Diseases|Diabetes Mellitus|Heart Diseases|Hypercholesterolemia|Hypertension|Obesity|Menopause|Postmenopause
Interventions: BEHAVIORAL: diet, fat-restricted
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: PREVENTION
Clinical trial: Phase I Trial of Vorinostat (MK-0683, SAHA) in Combination With Decitabine in Patients With AML or MDS (MK-0683-055 EXT1)
Status: COMPLETED
Conditions: Leukemia, Myelocytic, Acute Myelodysplastic Syndromes|Myelodysplastic Syndromes
Interventions: DRUG: vorinostat|DRUG: decitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Performance of a New Daily Disposable Contact Lens Worn in a Neophyte Population.
Status: COMPLETED
Conditions: Refractive Error|Myopia
Interventions: DEVICE: spectacles|DEVICE: narafilcon A soft contact lenses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Evaluation of PC-SOD for Injection in Reducing Myocardial Reperfusion Injury
Status: UNKNOWN
Conditions: Myocardial Reperfusion Injury
Interventions: DRUG: PC-SOD|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Improved Breast Cancer Therapy (I-BCT-1) in the Neoadjuvant and Metastatic Setting
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Carboplatin|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Total Knee Arthroplasty Infiltration Study for Postoperative Analgesia
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: HTX-011|DRUG: Saline Placebo|DRUG: Bupivicaine HCl|DRUG: Ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Laryngeal Mask Airway Supreme and Endotracheal Tube In Patients Undergoing Gynecological Laparoscopy Surgery
Status: COMPLETED
Conditions: Anaesthesia
Interventions: DEVICE: Endotracheal Tube|DEVICE: Laryngeal Mask Airway-Supreme
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: The Effect of Grape Seed Extract on Blood Pressure in People With Pre-Hypertension
Status: COMPLETED
Conditions: Hypertension
Interventions: DIETARY_SUPPLEMENT: grape seed extract|DIETARY_SUPPLEMENT: grape seed extract placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Hydrogel Balloon Assisted Intracranial Aneurysm Coiling Registry
Status: WITHDRAWN
Conditions: Intracranial Aneurysms|Aneurysm|Brain Aneurysm
Interventions: DEVICE: Balloon Assisted Coiling using MicroVention second-generation hydrogel coils and MicroVention Scepter Occlusion Balloon Catheter.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing the Efficacy of Two Topical Steroid Application Regimens in Pediatric Patients With Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: OTHER: Soak and smear|OTHER: Dry Smear
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Endoscopic Gastric Balloon Insertion on Obstructive Sleep Apnea in Patients With Morbid Obesity
Status: COMPLETED
Conditions: Morbid Obesity|Obstructive Sleep Apnea
Interventions: PROCEDURE: gastric balloon insertion
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating Atorvastatin With Omega-3 Fatty Acids in Cardiovascular Risk Reduction in Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes, Type 2
Interventions: DRUG: Atorvastatin and Omega-3 fatty acids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Gabapentin Treatment of Postural Tachycardia Syndrome (PoTS)
Status: COMPLETED
Conditions: Postural Orthostatic Tachycardia Syndrome
Interventions: DRUG: Gabapentin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Dapagliflozin on Body Weight in Overweight Women Consuming Different Proportions of Carbohydrate Diet.
Status: COMPLETED
Conditions: Overweight|Carbohydrate|Sodium-glucose Transporter 2 Inhibitors
Interventions: DRUG: Dapagliflozin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pharmacokinetics (PK) and Safety Study to Determine the Effect of Repeat Dosing of Trametinib on Combined Oral Contraceptive (Norethindrone Plus Ethinyl Estradiol) in Female Subjects With Solid Tumors
Status: WITHDRAWN
Conditions: Cancer
Interventions: DRUG: Trametinib 0.5 mg|DRUG: Trametinib 2 mg|DRUG: ORTHO-NOVUM® tablet 1/35|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Youth Engagement Study: Intervention to Increase HIV Treatment Engagement and Adherence for Young People Living With HIV
Status: COMPLETED
Conditions: HIV/AIDS
Interventions: BEHAVIORAL: Youth Engagement in Services
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 0.6 vs. 1.2 mg Atropine Together With Neostigmine 2.5 mg on Heart Rate in Patient Receiving Muscle Relaxant
Status: COMPLETED
Conditions: Bradycardia|Neostigmine Adverse Reaction|Adverse Reaction to Belladonna or Atropine
Interventions: DRUG: Atropine 0.6 mg|DRUG: Atropine 1.2 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Music-with-Movement Intervention for People With Early Dementia and Their Families
Status: COMPLETED
Conditions: Dementia|Anxiety|Sleep|Depression|Quality of Life
Interventions: BEHAVIORAL: Music with movement|BEHAVIORAL: Social interaction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Anti-aging Efficacy of Four Skin Health Products
Status: COMPLETED
Conditions: Anti-Aging|Skin Aging
Interventions: OTHER: Day Cream cosmetic product compared to untreated side|OTHER: Night cream cosmetic product compared to untreated side|OTHER: Eye cream cosmetic product compared to untreated side|OTHER: Serum cosmetic product compared to untreated side
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Coproporphyrine Isomers and Methotrexate Elimination
Status: COMPLETED
Conditions: Central Nervous System Neoplasms|Lymphoma, Large B-Cell, Diffuse|Precursor B-Cell Lymphoblastic Leukemia-Lymphoma|Burkitt Lymphoma
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p