pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Study of BTK Inhibitor Zanubrutinib in Participants With Relapsed/Refractory Non-GCB Type Diffuse Large B Cell Lymphoma
Status: COMPLETED
Conditions: Diffuse Large B-cell Lymphoma
Interventions: DRUG: Zanubrutinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Football Players Health Study In Person Assessments Study
Status: COMPLETED
Conditions: Cardiac Dysfunction|Neurocognitive Disease|Chronic Pain|Sleep Apnea
Interventions: DIAGNOSTIC_TEST: Echocardiography|DIAGNOSTIC_TEST: Neuropsychological Testing|DIAGNOSTIC_TEST: Quantitative Sensory Testing|DIAGNOSTIC_TEST: Nocturnal Polysomnography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Trial Of Azithromycin SR For The Treatment Of Acute Bronchitis And Secondary Infection Of Chronic Respiratory Diseases
Status: COMPLETED
Conditions: Acute Bronchitis
Interventions: DRUG: Azithromycin SR
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Autologous Bone Marrow Stromal Cell and Endothelial Progenitor Cell Transplantation in Ischemic Stroke
Status: COMPLETED
Conditions: Stroke|Infarction, Middle Cerebral Artery
Interventions: GENETIC: Autologous BMSCs transplantation|GENETIC: Autologous EPCs transplantation|GENETIC: IV infusion of placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized Control Trial Comparing Single vs. Multiple Application of Lidocaine Analgesia Prior to Urethral Catheterization Procedures
Status: COMPLETED
Conditions: Urinary Tract Infection|Kidney Diseases|Ureteral Diseases|Ureteral Obstruction
Interventions: BEHAVIORAL: observed levels of pain
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Effect of Food Order on Postprandial Glucose Excursions in Pre-Diabetes
Status: COMPLETED
Conditions: Obesity|Pre-Diabetes
Interventions: BEHAVIORAL: Food Order|BEHAVIORAL: Carbohydrate Last|BEHAVIORAL: Vegetables first
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Exploratory Study of Ganglioside GM1 in Acute Ischemic Stroke
Status: COMPLETED
Conditions: Stroke, Ischemic
Interventions: DRUG: Monosialoganglioside GM1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cemiplimab for the Treatment of Locally Advanced Head and Neck Basal Cell Carcinoma Before Surgery
Status: RECRUITING
Conditions: Locally Advanced Basal Cell Carcinoma
Interventions: BIOLOGICAL: Cemiplimab|PROCEDURE: Computed Tomography|PROCEDURE: Biospecimen Collection|OTHER: Quality-of-Life Assessment|PROCEDURE: Magnetic Resonance Imaging|PROCEDURE: Biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of An ACP Programme for Older People With Early Dementia
Status: COMPLETED
Conditions: Dementia, Mild
Interventions: BEHAVIORAL: Have A Say Programme|BEHAVIORAL: Attention-control health talks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Transcutaneous Electrical Nerve Stimulation for Endometriosis-related Chronic Pain
Status: RECRUITING
Conditions: Endometriosis-related Pain
Interventions: DEVICE: Transcutaneous electrical nerve stimulation (TENS)|OTHER: Conventional analgesic treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reducing Inequities in Care of Hypertension, Lifestyle Improvement for Everyone (RICH LIFE Project)
Status: COMPLETED
Conditions: Uncontrolled Hypertension
Interventions: BEHAVIORAL: Provider Audit-Feedback, Stratified by Race and Ethnicity|BEHAVIORAL: Blood Pressure Measurement Standardization|BEHAVIORAL: System Level Leadership Intervention|BEHAVIORAL: Collaborative Care Team Intervention|BEHAVIORAL: Community Health Worker Referral|BEHAVIORAL: Specialist Care Consultation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cross-linking of Corneal Collagen (CXL) With Ultraviolet-A in Asymmetric Corneas
Status: TERMINATED
Conditions: Keratoconus|Ectasia|Degeneration
Interventions: DRUG: Ciprofloxicin or Vigamox or other.|DRUG: Nonsteroidal (Acular, Acuvail, Voltaren Xibrom, etc)|DRUG: Steroid (FML, Pred Forte, Flarex, etc.)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pharmacokinetics, Safety and Tolerability of Treprostinil Inhalation Powder in Healthy Normal Volunteers
Status: COMPLETED
Conditions: Pulmonary Arterial Hypertension
Interventions: DRUG: Treprostinil Inhalation Powder
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Sapanisertib in Combination With Fulvestrant in Women With Advanced or Metastatic Breast Cancer After Aromatase Inhibitor Therapy
Status: COMPLETED
Conditions: Breast Neoplasms
Interventions: DRUG: Fulvestrant|DRUG: Sapanisertib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pediatric Hemiplegia: Synergistic Treatment Using rTMS and CIT
Status: COMPLETED
Conditions: Stroke
Interventions: DEVICE: real rTMS combined with constraint induced therapy|DEVICE: sham rTMS combined with constraint induced therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Propranolol in Treating Hypoglycemia Unawareness
Status: TERMINATED
Conditions: Type 1 Diabetes Mellitus
Interventions: DRUG: Propranolol 80 Mg Oral Capsule, Extended Release|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Negative Pressure Wound Therapy to Prevent Wound Complications Following Cesarean Section in High Risk Patients
Status: COMPLETED
Conditions: High Risk Pregnancy|Cesarean Wound Disruption With Postnatal Complication
Interventions: DEVICE: PICO Single Use Negative Pressure Wound Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Remote Rehabilitation Via the Internet in Patients After a Stroke - Physical Rehabilitation Using Biofeedback Systems to Improve Upper Extremity Function
Status: WITHDRAWN
Conditions: Stroke Patients
Interventions: DEVICE: Hand tutor rehabilitation device|DEVICE: Arm tutor rehabilitation device
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Ozenoxacin 1% Cream Versus Placebo in the Treatment of Patients With Impetigo
Status: COMPLETED
Conditions: Impetigo
Interventions: DRUG: Ozenoxacin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Darbepoetin Alfa in Anemic Subjects With Low Risk Myelodysplastic Syndrome
Status: COMPLETED
Conditions: Myelodysplastic Syndromes
Interventions: DRUG: Darbepoetin Alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TAK-875 (Fasiglifam) in Combination With Sitagliptin in Adults With Type 2 Diabetes
Status: TERMINATED
Conditions: Diabetes
Interventions: DRUG: Placebo|DRUG: TAK-875|DRUG: TAK-875
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Immune Responses After Vaccination With Two Investigational RNA-based Vaccines Against Tuberculosis in BCG Vaccinated Volunteers
Status: ACTIVE_NOT_RECRUITING
Conditions: Tuberculosis
Interventions: BIOLOGICAL: BNT164a1|BIOLOGICAL: BNT164b1|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Safety and Efficacy of Axatilimab in Combination With Ruxolitinib in Participants With Newly Diagnosed Chronic Graft-Versus-Host Disease
Status: NOT_YET_RECRUITING
Conditions: Chronic Graft-versus-host-disease
Interventions: DRUG: Axatilimab|DRUG: Ruxolitinib|DRUG: Corticosteroids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Chronic Mountain Sickness
Status: UNKNOWN
Conditions: Hypoxia, Altitude
Interventions: DRUG: Acetazolamide|DRUG: Atorvastatin|DRUG: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Low-pressure Pneumoperitoneum on Pain and Inflammation in Laparoscopic Cholecystectomy
Status: COMPLETED
Conditions: Pneumoperitoneum|Pain|Inflammatory Response
Interventions: PROCEDURE: low-pressure pneumoperitoneum|PROCEDURE: standard-pressure pneumoperitoneum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of AHCL Insulin Pump on Glycemic Control and Psychosocial Outcomes in Pediatric Patients With Type 1 Diabetes
Status: RECRUITING
Conditions: Type 1 Diabetes
Interventions: DEVICE: Medtronic 780G insulin pump
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Differing Cognitive Task Demands on Whole-body Energy Metabolism and Cerebral Blood-flow: Modulation by Multivitamins/Minerals and Coenzyme Q10
Status: COMPLETED
Conditions: Metabolic Processes
Interventions: DIETARY_SUPPLEMENT: Supradyn® (1RDA+CoQ10)|DIETARY_SUPPLEMENT: Supradyn® (3RDA)|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Characterization of the Temporo-masseteric Nerve Block (TMNB) in Healthy Subjects
Status: RECRUITING
Conditions: Occlusion
Interventions: DRUG: Temporomasseteric Nerve Block
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Assessment of the Efficacy of Rosuvastatin in Patient Groups With a Dissimilar Risk Profile in an Observational Study (HEROS)
Status: COMPLETED
Conditions: Hypercholesterolemia|Coronary Heart Disease|Peripheral Vascular Disease|Cerebrovascular Accident|Diabetes
Interventions: DRUG: Rosuvastatin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Breast Cancer Survivorship Biorepository
Status: RECRUITING
Conditions: Anatomic Stage I Breast Cancer AJCC v8|Anatomic Stage II Breast Cancer AJCC v8|Anatomic Stage III Breast Cancer AJCC v8|Invasive Breast Carcinoma
Interventions: PROCEDURE: Biospecimen Collection|OTHER: Electronic Health Record Review|OTHER: Quality-of-Life Assessment|OTHER: Survey Administration
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: HFNC and Hypoxia/Desaturation During Radiofrequency Ablation Under Moderate Sedation: A Randomized Clinical Trial
Status: COMPLETED
Conditions: Propofol|Hypoxia|Sedation Complication|Desaturation of Blood
Interventions: DEVICE: high-flow oxygen nasal cannula therapy|OTHER: nasal cannula oxygen therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Multi-Method Health System Quality Improvement Intervention to Reduce Hypertension Disparities
Status: COMPLETED
Conditions: Hypertension
Interventions: BEHAVIORAL: Improve clinic based measurement of blood pressure|BEHAVIORAL: Provider education system to promote patient-centered care|BEHAVIORAL: Introduce care management system in clinics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Benefit of Acupuncture Combined to Regional Analgesia for Post Operative Pain Relief After Hysterectomy
Status: RECRUITING
Conditions: Pain, Postoperative
Interventions: PROCEDURE: Acupuncture|PROCEDURE: Bilateral ESP catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Development and Validation of a Sputum Biomarker mRNA Panel for the Diagnostic Work-up of Asthma 3
Status: TERMINATED
Conditions: Asthmatic Patients
Interventions: DRUG: Montelukast|DRUG: long acting beta2 mimetic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I/II, Multicenter, Open-label Study of EGFRmut-TKI EGF816, Administered Orally in Adult Patients With EGFRmut Solid Malignancies
Status: COMPLETED
Conditions: Advanced Non-small Cell Lung Cancer
Interventions: DRUG: EGF816
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Haploidentical Allogeneic Transplant With Post-transplant Infusion of Regulatory T-cells
Status: TERMINATED
Conditions: Leukemia, Acute|Chronic Myelogenous Leukemia (CML)|Myelodysplastic Syndrome (MDS)|Non-Hodgkin Lymphoma (NHL)|Chronic Lymphocytic Leukemia (CLL)|Acute Myelogenous Leukemia (AML)|Acute Lymphoblastic Leukemia (ALL)
Interventions: DRUG: Regulatory T-cells|DRUG: Conventional T-cells|DRUG: Melphalan|DRUG: Thiotepa|DEVICE: Fludarabine|DRUG: Anti-thymocyte globulin, rabbit|DRUG: CliniMACS CD34 Reagent System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Intervention for Information Processing Speed Deficits in Acute SCI: A Pilot Study
Status: RECRUITING
Conditions: Spinal Cord Injuries|Cognitive Dysfunction|Cognitive Impairment|Acute Spinal Cord Injury
Interventions: BEHAVIORAL: game-like computerized activities|BEHAVIORAL: game-like computerized activities
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: T-cell Depleted Alternative Donor Transplantation
Status: TERMINATED
Conditions: Acute Lymphoblastic Leukemia|Acute Myeloid Leukemia|Chronic Myeloid Leukemia|Myelodysplastic Syndrome|Lymphomas|Bone Marrow Failure|Hemoglobinopathy|Immune Deficiency|Osteopetrosis
Interventions: DEVICE: CliniMACS® (T cell depletion)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Digital Pathology and AI for Liver Outcomes in MASLD
Status: NOT_YET_RECRUITING
Conditions: Metabolic Dysfunction-associated Steatotic Liver Disease
Interventions: DIAGNOSTIC_TEST: Digital Pathology FibroNest Phenotypic Fibrosis Composite Score (Ph-FCS)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of Culture-specific Popular Music as a Mental Metronome for Cardiopulmonary Resuscitation
Status: COMPLETED
Conditions: Cardiac Arrest|Out-of-hospital Cardiac Arrest
Interventions: BEHAVIORAL: Count on me Singapore (COMS) CPR|BEHAVIORAL: Standard CPR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Central Executive Training (CET) for ADHD
Status: RECRUITING
Conditions: ADHD
Interventions: BEHAVIORAL: Central Executive Training: Working Memory|BEHAVIORAL: Central Executive Training: Inhibitory Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Electromagnetic Navigation System Versus Freehand Technique in Total Hip Arthroplasty
Status: COMPLETED
Conditions: Hip Osteoarthritis
Interventions: PROCEDURE: Electromagnetic navigation|PROCEDURE: Freehand
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Reprieve Cardiovascular System for the Treatment of Subjects With Acute Decompensated Heart Failure Mechanistic Study
Status: COMPLETED
Conditions: Heart Failure
Interventions: OTHER: Fluid Management|DEVICE: Reprieve Cardiovascular System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Active Immunotherapy With OBI-833 (Globo H-CRM197) in Advanced/Metastatic Gastric, Lung, Colorectal or Breast Cancer Subjects
Status: COMPLETED
Conditions: Metastatic Gastric Cancer|Metastatic Breast Cancer|Metastatic Colorectal Cancer|Metastatic Lung Cancer
Interventions: DRUG: OBI-833/OBI-821
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultherapy® for the Treatment of Acne Scars
Status: COMPLETED
Conditions: Acne Scars|Atrophic Acne Scars
Interventions: DEVICE: Ultherapy® treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial to Determine Whether Two Differing Strength Tablets (3 x 5 mg Versus 1 x 15 mg) of Sublingually Org 5222 (Asenapine) Are Safe and Equal in Subjects With Schizophrenia or Schizoaffective Disorder (P05937)
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder
Interventions: DRUG: Asenapine 3x5mg followed by 1x15mg|DRUG: Asenapine 1x15mg followed by 3x5mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effectiveness of Mindfulness Based Meditation on Well-being, Self Compassion & Cognizance Among Nurses Working in Intensive Care Units
Status: COMPLETED
Conditions: Mindfulness is a Moment by Moment Awareness to Remain Purposefully and Non Judgmentally Attentive to Their Own Experience
Interventions: OTHER: Mindfulness Based Guided Meditation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of Dual Therapy With Dabigatran vs. Triple Therapy With Warfarin in Patients With AF That Undergo a PCI With Stenting (REDUAL-PCI)
Status: COMPLETED
Conditions: Atrial Fibrillation|Percutaneous Coronary Intervention
Interventions: DRUG: Dabigatran Etexilate 110mg|DRUG: Warfarin 3mg|DRUG: Aspirin|DRUG: Dabigatran Etexilate 150mg|DRUG: Clopidogrel or Ticagrelor|DRUG: Clopidogrel or Ticagrelor|DRUG: Warfarin 5mg|DRUG: Clopidogrel or Ticagrelor|DRUG: Warfarin 1mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety of NBP608 Compared to Zostavax in Healthy Adult Aged 50 and Over
Status: COMPLETED
Conditions: Herpes Zoster
Interventions: BIOLOGICAL: NBP608|BIOLOGICAL: Zostavax
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Delirium, Intraoperative Cerebral Perfusion and EEG Abnormalities After Total Hip Arthroplasty
Status: TERMINATED
Conditions: Delirium|Hip Arthroplasty|Elderly
Interventions: PROCEDURE: Blood Draw|PROCEDURE: Cerebral Spinal Fluid collection|DEVICE: Electroencephalogram|DEVICE: Cerebral blood flow and oxygen extraction fraction
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety Study Of SNX-5422 To Treat Solid Tumor Cancers And Lymphomas
Status: COMPLETED
Conditions: Solid Tumor Malignancy|Lymphoid Malignancy (Lymphoma and CLL)|Leukemia|Lymphoma
Interventions: DRUG: SNX-5422 Mesylate Hsp90 inhibitor
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized, Double-masked, Multicenter,Sham-controlled, Safety and Efficacy Study of KH902 in Patients With Wet AMD
Status: COMPLETED
Conditions: Neovascular Age-related Macular Degeneration
Interventions: BIOLOGICAL: Recombinant Human VEGF Receptor-Fc Fusion Protein
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hypertensive Ambulatory Trial to Compare the Efficacy of HCTZ and Lisinopril
Status: COMPLETED
Conditions: Hypertension, Grade 1|Hypertension Treatment|N of 1 Study Design|Hypertension
Interventions: DRUG: Lisinopril|DRUG: Hydrochlorothiazide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety of Recombinant Zoster Vaccine in People Living With HIV
Status: RECRUITING
Conditions: Vaccination; Infection|Vaccine Adverse Reaction
Interventions: BIOLOGICAL: Recombinant zoster vaccination
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Atherectomy Followed With a Drug Coated Balloon in the Treatment of Long Femoropopliteal Lesions
Status: NOT_YET_RECRUITING
Conditions: Peripheral Arterial Disease
Interventions: DEVICE: Atherectomy+Drug-coated balloon|DEVICE: Drug-coated balloon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Scaling Up Maternal Mental Healthcare by Increasing Access to Treatment (SUMMIT)
Status: ACTIVE_NOT_RECRUITING
Conditions: Perinatal Depression
Interventions: BEHAVIORAL: Brief Behavioral Activation Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Influence of Perioperative Fluid Management on Intraocular Pressure During Hynecologic Laparoscopic Pelvic Surgery
Status: UNKNOWN
Conditions: Influence of Perioperative Fluid Regime on Intraocular Pressure During Laparoscopic Gynecologic Surgery
Interventions: DRUG: ringer lactate solution|OTHER: restrictive fluid regime
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Trap and Reggaeton Music on Movement Velocity, Power and Muscular Endurance in the Lower Limbs of Physically Active Women
Status: COMPLETED
Conditions: Female|Sports|Muscle|Exercise
Interventions: OTHER: Effect of music on the manifestation of strength
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Baricitinib for Reduction of HIV - CNS
Status: RECRUITING
Conditions: Human Immunodeficiency Virus
Interventions: DRUG: Baricitinib 2 MG Oral Tablet|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Safety and PK Study of OLT1177 Capsules
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: OLT1177 Capsules|DRUG: Placebo Capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Response to Tregs in Innate Immunity Receptor LRP1 (CD91) and Tregs in Periferic Blood Mononuclear Cells in Patients With Non-segmentary Vitiligo
Status: COMPLETED
Conditions: VITILIGO
Interventions: DIAGNOSTIC_TEST: CD 91 levels|DIAGNOSTIC_TEST: Tregs
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety Study of ESBA1008 Versus EYLEA®
Status: COMPLETED
Conditions: Exudative Age-Related Macular Degeneration
Interventions: DRUG: ESBA1008 solution|DRUG: Aflibercept
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Low vs Moderate-intensity Endurance Exercise on Physical Functioning Among Breast Cancer Survivors
Status: COMPLETED
Conditions: Breast Neoplasms
Interventions: BEHAVIORAL: Exercise Program Low Intensity|BEHAVIORAL: Exercise Program Moderate Intensity
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy and Safety of Vibrating Capsule in Patients With Functional Constipation
Status: COMPLETED
Conditions: Functional Constipation|Gastrointestinal Disease|Capsule Endoscopy
Interventions: DEVICE: Sallowing VC during six weeks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Placebo Controlled Study of Homeopathic Treatment of Children and Youth With ADHD
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: DRUG: lactose/sucrose granule (Individualized homeopathic medicine treatment)|DRUG: Placebo lactose/sucrose pill|BEHAVIORAL: Homeopathic consultation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Islet Transplantation in Type 1 Diabetic Kidney Allograft
Status: RECRUITING
Conditions: Diabetes Mellitus, Type 1
Interventions: BIOLOGICAL: Allogenic islet cells (human, U. Chicago)|PROCEDURE: Intraportal infusion of islet cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Orem's Self-Care Deficit Theory Based Nursing Interventions for Immunotherapy Treated Cancer Patients
Status: COMPLETED
Conditions: Cancer|Nurse's Role|Treatment Side Effects|Quality of Life
Interventions: OTHER: Orem's Self-Care Deficit Theory Based Nursing Interventions for Immunotherapy Treated Cancer Patients
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Androgen Receptor Signaling and Prostate-Specific Membrane Antigen Expression
Status: RECRUITING
Conditions: Prostate Adenocarcinoma|Prostate Cancer|Metastatic Hormone-Sensitive Prostate Cancer (mHSPC)
Interventions: DRUG: Apalutamide [Erleada], darolutamide [Nubeqa], or enzalutamide [Xtandi]|DIAGNOSTIC_TEST: Prostate-Specific Membrane Antigen (PSMA) PET/CT Scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Exercise and Vestibular Hypofunction
Status: RECRUITING
Conditions: Vestibular Disease|Vestibular Disorder|Vestibular Vertigo
Interventions: OTHER: Exercise for bilateral or unilateral vestibular hypofunction patients|OTHER: Conventional rehabilitation treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Double Blind Crossover Trial of Levetiracetam (Keppra®) and Placebo in the Treatment of Restless Legs Syndrome (RLS)
Status: COMPLETED
Conditions: Restless Legs Syndrome
Interventions: DRUG: Levetiracetam (Keppra)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Study of Rivaroxaban for CeREbral Venous Thrombosis
Status: COMPLETED
Conditions: Cerebral Venous Thrombosis
Interventions: DRUG: Rivaroxaban|DRUG: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Mediators of Sensitivity and Resistance to Nivolumab Plus Ipilimumab in Patients With Advanced NSCLCs
Status: COMPLETED
Conditions: Advanced Stage Non-small Cell Lung Cancer
Interventions: DRUG: nivolumab|DRUG: pilimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I Study of AbGn-168H in Healthy Male Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: AbGn-168H|DRUG: AbGn-168H|DRUG: Placebo|DRUG: Placebo|DRUG: Placebo|DRUG: Placebo|DRUG: AbGn-168H|DRUG: AbGn-168H|DRUG: AbGn-168H|DRUG: Placebo|DRUG: Placebo|DRUG: AbGn-168H
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Intravaginal Treatment of Disturbances of Vaginal Flora Among HIV Infected and Uninfected Women in Malawi
Status: COMPLETED
Conditions: Bacterial Vaginosis|Trichomonas Vaginitis|Urogenital Diseases
Interventions: DRUG: Metronidazole gel versus placebo gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Comparing Smoking Cessation Interventions Among Underserved Patients Referred for Lung Cancer Screening
Status: ACTIVE_NOT_RECRUITING
Conditions: Smoking Cessation
Interventions: BEHAVIORAL: Removal of Financial Barriers|BEHAVIORAL: Financial Incentives|BEHAVIORAL: Mobile Health Application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study Of An Investigational Regimen Including Marketed HIV Drugs In HIV-1 Pediatric Subjects Ages 2-18 Years
Status: COMPLETED
Conditions: HIV Infection
Interventions: DRUG: ritonavir|DRUG: fosamprenavir
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Insulin Pump vs Multiple Daily Injections of Insulin and Glyco-metabolic Control in Type 1 Diabetic Patients
Status: RECRUITING
Conditions: Type 1 Diabetes Mellitus
Interventions: DEVICE: Insulin pump|DRUG: Insulin injections
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dual Antiplatelet Therapy For Shock Patients With Acute Myocardial Infarction
Status: RECRUITING
Conditions: Acute Myocardial Infarction|Cardiogenic Shock
Interventions: DRUG: Cangrelor|DRUG: Ticagrelor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intrathecal Morphine Versus Morphine-dexmedetomidine Combination for Postoperative Pain Control After Total Knee Replacement
Status: COMPLETED
Conditions: Intrathecal Morphine|Intrathecal Morphine-dexmedetomidine Combination|Postoperative Pain Control|Total Knee Replacement
Interventions: DRUG: Dexmedetomidine|DRUG: Morphine|DRUG: Dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Endotracheal Intubation Without Muscle Relaxants
Status: COMPLETED
Conditions: Muscle Relaxation|Intubation Complication
Interventions: OTHER: Avoidance of rocuronium/cisatracurium|DRUG: Sevoflurane 8% + Intravenous fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Qigong on Balance, Fall Efficacy, Wellbeing of People With Stroke in Hong Kong
Status: UNKNOWN
Conditions: Stroke
Interventions: OTHER: Qigong|OTHER: Fitness exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rehabilitative Therapy and Pridinol in Patients With Lumbar Spondylarthrosis and Chronic Low Back Pain
Status: COMPLETED
Conditions: Spondyloarthropathy
Interventions: OTHER: Rehabilitation + Drug therapy|OTHER: Rehabilitation|OTHER: Drug therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Effects of Different Tooth Brushing Explanations in Fixed Orthodontic Treatment
Status: COMPLETED
Conditions: Orthodontic Treatment|Dental Plaque Induced Gingival Disease
Interventions: OTHER: Tooth brushing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MDMA-Assisted Psychotherapy in People With Posttraumatic Stress Disorder
Status: COMPLETED
Conditions: Posttraumatic Stress Disorder
Interventions: DRUG: Midomafetamine|DRUG: Lactose placebo pill|BEHAVIORAL: Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Chronoterapy in Oral Surgery
Status: COMPLETED
Conditions: Tooth, Impacted|Trismus|Pain|Inflammatory Response
Interventions: DRUG: Ibuprofen 400 mg|DRUG: Ibuprofen 400 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Study Investigating the Safety, Tolerability, and Pharmacokinetics of MTP-131 in Subjects With Congestive Heart Failure
Status: COMPLETED
Conditions: Congestive Heart Failure
Interventions: DRUG: MTP-131|DRUG: MTP-131|DRUG: MTP-131|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 4 Study of Dolutegravir (DTG) in Russian Federation
Status: COMPLETED
Conditions: Infection, Human Immunodeficiency Virus|HIV Infections
Interventions: DRUG: Dolutegravir 50 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Visual Performance of Two Types of Cosmetic Contact Lenses
Status: COMPLETED
Conditions: Visual Acuity
Interventions: DEVICE: etafilcon A with cosmetic pattern|DEVICE: 1-Day Acuvue DEFINE Vivid Style
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Effects of Tramadol Hydrochloride on Cardiac Repolarization in Healthy Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Tramadol HCl|DRUG: Moxifloxacin 400 mg|DRUG: Tramadol HCl Placebo|DRUG: Moxifloxacin Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Audiovestibular Function in Infratentorial Superficial Siderosis
Status: COMPLETED
Conditions: Siderosis|Neurological Disorder|Rare Diseases|Age Related Hearing Loss|Presbycusis
Interventions: DIAGNOSTIC_TEST: Hearing assessment|DIAGNOSTIC_TEST: Vestibular/balance assessment|OTHER: Quality of life assessment|DIAGNOSTIC_TEST: Olfactory (smell) function testing|GENETIC: DNA bio-banking
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Testosterone Replacement Therapy in Chronic Spinal Cord Injury
Status: COMPLETED
Conditions: Spinal Cord Injury|Hypogonadism
Interventions: DRUG: Testosterone Transdermal System (Androderm 5 mg patch)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Change in Child-feeding Knowledge, Attitudes, and Practices With Nutrition Education Mass Media in Ghana
Status: COMPLETED
Conditions: Health Education, Community|Diet, Food, and Nutrition|Malnutrition|Infant Nutritional Sciences
Interventions: BEHAVIORAL: Active mass media approach|BEHAVIORAL: Passive mass media approach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Transcranial Direct Current Stimulation in Post-stroke Fatigue
Status: COMPLETED
Conditions: Fatigue|Stroke
Interventions: DEVICE: Anodal tDCS|DEVICE: sham tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Fluoropyrimidine Tailored-dose Based on Uracil Concentration in Patients Treated for Digestive Carcinomas: Evaluation of Clinical Practice
Status: COMPLETED
Conditions: Digestive Carcinoma
Interventions: DRUG: Fluoropyrimidine treatment (5-FU or capecitabine) and dosage|OTHER: Uracil dosage|BEHAVIORAL: Overall survival
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Systemic and Local Antimicrobials in the Management of Dental Abscess in Children
Status: COMPLETED
Conditions: Dentoalveolar Abscess
Interventions: DRUG: Odontopaste®|DRUG: Pulpdent|DRUG: Amoxicillin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Combining Chinese Medicine and Nutrition to Enhance Weight Loss After Bariatric Surgery
Status: RECRUITING
Conditions: Traditional Chinese Medicine Treatment|Weight Change
Interventions: DRUG: Spleen Invigorating and Weight Reducing Decoction|OTHER: Diet and meal replacements
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Product Validation Study of RightSpot Infant pH Indicator for Rapid Bedside Verification of Proper Nasogastric (NG) Tube Placement in Newborn Intensive Care (NICU) Patients
Status: UNKNOWN
Conditions: Establish Normative pH Values in Neonates
Interventions: DEVICE: RightSpot Infant pH Indicator
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Joint Pain and Medication Adherence in Postmenopausal Women Receiving Aromatase Inhibitors
Status: COMPLETED
Conditions: Arthralgia|Breast Cancer
Interventions: OTHER: aromatase inhibition therapy - OBSERVATIONAL ONLY|OTHER: medical chart review|OTHER: questionnaire administration|PROCEDURE: assessment of therapy complications
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Virtual Reality Distraction for Procedural Pain Management in Children With Burn Injuries: a Randomized Controlled Trial
Status: COMPLETED
Conditions: Burns|Child|Pain
Interventions: DEVICE: Virtual Reality Prototype|OTHER: Standard Pharmacological Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasound in Assessing Antiangiogenic Treatment in Patients With Advanced Kidney Cancer
Status: UNKNOWN
Conditions: Kidney Cancer|Metastatic Cancer
Interventions: DRUG: antiangiogenesis therapy|DRUG: stabilized sulphur hexafluoride microbubble-based contrast agent|OTHER: imaging biomarker analysis|OTHER: pharmacological study|PROCEDURE: computed tomography|PROCEDURE: magnetic resonance imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: DIAGNOSTIC
Clinical trial: Diagnostic Accuracy of the "LLIFT", a Novel Non-invasive Biomarker for the Diagnosis of Non Alcoholic Fatty Liver (NAFL) and SteatoHepatitis (NASH) in a Population With High Risk of Metabolic Syndrome"
Status: RECRUITING
Conditions: Obesity|NASH - Nonalcoholic Steatohepatitis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: HFNC Versus Conventional Oxygen Therapy in Prolonged Upper Gastrointestinal Endoscopy in the ICU
Status: RECRUITING
Conditions: Upper Gastrointestinal Bleeding
Interventions: DEVICE: High-flow nasal cannula (HFNC)|DEVICE: Conventional nasal oxygen therapy (COT)|DEVICE: Upper gastrointestinal endoscopy (UGE) including gastroscopy|DEVICE: Upper gastrointestinal endoscopy (UGE) including Endoscopic ultrasound (EUA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Bioequivalence Study of 8 mg Perindopril Tert-Butylamine / 2.5 mg Indapamide / 10 mg Amlodipine Tablets Versus 10 mg Perindopril Arginine / 2.5 mg Indapamide / 10 mg Amlodipine Film-Coated Tablets in Healthy Volunteers
Status: COMPLETED
Conditions: Bioequivalence|Healthy Subjects
Interventions: DRUG: PERINDOPRES® TRIO, 8 mg perindopril tert-butylamine / 2.5 mg indapamide / 10 mg amlodipine tablets|DRUG: TRIPLIXAM® 10 mg /2.5 mg/10 mg, 10 mg perindopril arginine / 2.5 mg indapamide / 10 mg amlodipine film-coated tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effect of Vitamin D3 and Omega-3FA on Estradiol
Status: COMPLETED
Conditions: Vitamin D Deficiency
Interventions: DIETARY_SUPPLEMENT: VD3|DIETARY_SUPPLEMENT: Omega3-FA|DIETARY_SUPPLEMENT: VD3 and Omega-3FA|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: BRACE(Balance, Resistance, Aerobic and Cognitive Exercise) Protocol for Diabetic).Peripheral Neuropathic Patients.
Status: UNKNOWN
Conditions: Diabetic Peripheral Neuropathy (DPN)
Interventions: OTHER: RACE Protocol: Balance training along with resistance, aerobic and cognitive exercises.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Efficacy, Safety, and Tolerability Study Comparing Dolutegravir (DTG) Plus Lamivudine (3TC) With Dolutegravir Plus Tenofovir/Emtricitabine in Treatment naïve HIV Infected Participants (Gemini 2)
Status: COMPLETED
Conditions: Infection, Human Immunodeficiency Virus|HIV Infections
Interventions: DRUG: Dolutegravir (DTG)|DRUG: Lamivudine (3TC)|DRUG: Tenofovir disoproxil fumarate/Emtricitabine (TDF/FTC FDC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Validation of Brief Computerized Cognitive Assessment in Multiple Sclerosis (BCCAMS)
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: BEHAVIORAL: Cognitive evaluation|BEHAVIORAL: Expanded Disability Status Scale (EDSS) score
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Nicotinamide Riboside and Metabolic Health
Status: COMPLETED
Conditions: Obesity|Insulin Resistance
Interventions: DIETARY_SUPPLEMENT: Nicotinamide Riboside (Niagen)|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Gemcitabine Plus Nab-paclitaxel Versus S1 Plus Nab-paclitaxel in Metastatic Adenocarcinoma of the Pancreas
Status: UNKNOWN
Conditions: Pancreatic Cancer|Nab-paclitaxel|Gemcitabine|S1
Interventions: DRUG: S1 or Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Food-effect Study on Uracil and Dihydrouracil Levels as a Diagnostic Marker of Dihydropyrimidine Dehydrogenase Activity
Status: UNKNOWN
Conditions: Drug Safety Biomarkers
Interventions: OTHER: Test meal (breakfast)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Vitamin D Supplementation on Endothelial Function in Obese Adolescents
Status: COMPLETED
Conditions: Obesity|Endothelial Dysfunction|Vitamin D Deficiency
Interventions: DIETARY_SUPPLEMENT: Vitamin D3
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: eDENT Oral Health- the Gateway to Quality of Care and Everyday Life at Old Age
Status: COMPLETED
Conditions: Mild Cognitive Impairment|Gingivitis|Periodontal Diseases
Interventions: DEVICE: Reminder function on Android computer tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Resistance Training in Cardiovascular Disease Patients
Status: UNKNOWN
Conditions: Coronary Artery Disease|Heart Failure With Reduced Ejection Fraction
Interventions: OTHER: Aerobic interval training combined with high intensity resistance training|OTHER: Aerobic interval training combined with low intensity resistance training|OTHER: Aerobic interval training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety & Effectiveness of Autologous Regenerative Cell Therapy on Pain & Inflammation of Osteoarthritis of the Hip
Status: RECRUITING
Conditions: Osteoarthritis
Interventions: BIOLOGICAL: [StroMed + platelet rich plasma (PRP)]
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT