pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Sex and Exercise-mode Differences in Post Exercise Blood Pressure and Heart Rate Variability Responses During Workday
Status: COMPLETED
Conditions: Hemodynamic|Exercise
Interventions: OTHER: Aerobic exercise|OTHER: Resistance exercise|OTHER: Control session
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: BIOLUX P-II First-in-Man Study to Compare the Passeo-18 Lux DRB Against POBA in Infrapopliteal Arteries
Status: COMPLETED
Conditions: Atherosclerosis|Arteriosclerosis|Vascular Disease|Peripheral Artery Disease
Interventions: DEVICE: Passeo-18 Lux DRB|DEVICE: Standard PTA (POBA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Blood Sparing Strategies: Omni-stat Routinary Use in Cardiac Surgery. A Prospective Randomized Study.
Status: TERMINATED
Conditions: Hemostasis
Interventions: DRUG: Omni-stat Celox|DRUG: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Vascular Function and Biomarker Assessments in Healthy Volunteers and in Patients With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Other|DRUG: Other
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Medial Patellofemoral Ligament Reconstruction in Children - a 2-8 Years Follow-up Study
Status: RECRUITING
Conditions: Medial Patellofemoral Dislocation|Medial Patellofemoral Ligament Reconstruction
Interventions: OTHER: MPFL-reconstruction
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of a Phosphate Modified Diet on Phosphate Balance and Phosphate Metabolism in Predialysis Patients Stage 3-4
Status: COMPLETED
Conditions: Chronic Kidney Disease
Interventions: OTHER: Diet with phosphate containing additives|OTHER: Diet without phosphate containing additives
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Medium Chain Triglyceride Intervention for Patients With Alzheimer Disease
Status: UNKNOWN
Conditions: Alzheimer's Disease
Interventions: DIETARY_SUPPLEMENT: Ketogenic medium chain triglyceride drink (MCT drink)|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Long-Term Followup and/or Thalidomide Maintenance Therapy for Patients Enrolled on Clinical Trial 20030165
Status: COMPLETED
Conditions: Mantle Cell Lymphoma|Non-Hodgkin's Lymphoma
Interventions: DRUG: Thalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Efficacy Studies of Panobinostat and Bicalutamide in Patients With Recurrent Prostate Cancer After Castration
Status: COMPLETED
Conditions: Prostate Cancer|Prostatic Neoplasms
Interventions: DRUG: Panobinostat|DRUG: Bicalutamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nasal Photodisinfection COVID-19 Proof of Concept Study
Status: COMPLETED
Conditions: COVID-19|Corona Virus Infection|SARS-CoV 2
Interventions: OTHER: Methylene-Blue Photodisinfection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial Investigating the Efficacy and Safety of Flexible vs. Fixed Dosing and Simple vs. Stepwise Titration With Once Daily (OD) Insulin Degludec in Inadequately Treated Subjects With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: insulin degludec|DRUG: insulin degludec|DRUG: insulin degludec
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Healthy Food First
Status: ACTIVE_NOT_RECRUITING
Conditions: Hypertension|Food Insecurity|Diet, Mediterranean
Interventions: OTHER: Food Subsidy, 6 months|OTHER: Food Subsidy, 12 months|BEHAVIORAL: Lifestyle Support, 6 months|BEHAVIORAL: Lifestyle Support, 12 months|OTHER: Food Delivery, 6 months|OTHER: Food Delivery, 12 months
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Neuropsychological and Biopsychosocial Evolution During Pediatric Transplantation: Pre/Post-stages and at 6 Months
Status: RECRUITING
Conditions: Transplant-Related Disorder
Interventions: PROCEDURE: Allogeneic hematopoietic stem cell transplantation|PROCEDURE: Solid organ transplantation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase 2 Single-Arm Open-Label Pilot Trial Evaluating Zanidatamab (ZW25) in Patients With Early Stage HER2/Neu Positive (HER2+) Breast Cancer (BC)
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer|HER2-positive
Interventions: DRUG: Zanidatamab|DRUG: Letrozole|DRUG: Tamoxifen
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PLAI-AF Trial: Hybrid Endo-epicardial Partial Left Atrial Isolation vs. Endocardial Ablation in Patients With Persistent Atrial Fibrillation
Status: RECRUITING
Conditions: Atrial Fibrillation|Persistent Atrial Fibrillation|Arrythmia
Interventions: PROCEDURE: Partial Left Atrial Isolation|PROCEDURE: Catheter Ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of the Use of Gel Pillows on the Sleep Quality and General Comfort Levels
Status: COMPLETED
Conditions: Preoperative|Sleep|Comfort
Interventions: OTHER: Using a gel pillow
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy and Safety of Tildrakizumab 100 Milligrams (mg) in Participants With Moderate-Severe Chronic Plaque Psoriasis and Its Impact on Their Quality of Life (TRIBUTE)
Status: COMPLETED
Conditions: Plaque Psoriasis
Interventions: DRUG: Tildrakizumab 100 mg Solution for Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of a Newly 23-valent Pneumococcal Polysaccharide Vaccine in Chinese Adults and Children
Status: COMPLETED
Conditions: Pneumococcal Infectious Diseases
Interventions: BIOLOGICAL: vaccination PPV23|BIOLOGICAL: vaccination PNEUMOVAX 23
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Effects of GABA-a-Agonists on Pain Mechanisms: An Experimental Study in Healthy Volunteers
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: clobazam|DRUG: clonazepam|DRUG: tolterodine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness and Safety of Electroacupuncture on Poststroke Urinary Incontinence
Status: COMPLETED
Conditions: Urinary Incontinence|Stroke, Complication
Interventions: DEVICE: Electroacupuncture (EA)|DEVICE: Sham electroacupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Efficacy of 『Opast Tablet』for Neurologic Claudication in Patients With Lumbar Spinal Stenosis
Status: COMPLETED
Conditions: Neurologic Claudication in Patients With Lumbar Spinal Stenosis
Interventions: DRUG: Limaprost|DRUG: Pregabalin|DRUG: Placebo(for Pregabalin)|DRUG: Placebo(for Limaprost)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Robotic Versus Laparoscopic Roux En-y Gastric Bypass
Status: COMPLETED
Conditions: Roux-en-y Anastomosis Site|Obesity, Morbid|Bypass Complication|Anastomosis; Complications|Surgery-Complications
Interventions: PROCEDURE: Roux en-Y gastric bypass
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pharmacokinetic Study in Healthy Adult Volunteers to Assess the Interactions Between Steady-State Tipranavir and Atazanavir in the Presence of Ritonavir
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Tipranavir|DRUG: Ritonavir|DRUG: Atazanavir
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics of Sufentanil Sublingual Microtablet 30 mcg and 15 mcg in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Treatment Arm A: Sufenta®|DRUG: Treatment B: Sufentanil SSM 30 mcg|DRUG: Treatment C: SSM 15 mcg|DRUG: Treatment D: SSM 30 mcg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Allopurinol and Quality of Life in Liver Cirrhosis
Status: COMPLETED
Conditions: Cirrhosis, Liver
Interventions: DRUG: Allopurinol Tablet|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PharmacofMRI of Anxiolytic Medications (Pregabalin)
Status: COMPLETED
Conditions: Anxiety Disorders
Interventions: DRUG: Pregabalin 50mg|DRUG: Pregabalin 200 MG|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Canine Guidance vs Bilateral Balanced Occlusion in Complete Denture
Status: COMPLETED
Conditions: Edentulous Mouth|Edentulous Jaw
Interventions: PROCEDURE: Occlusal scheme
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II Study of Arginine Butyrate With or Without Epoetin Alfa in Patients With Thalassemia Intermedia
Status: COMPLETED
Conditions: Beta-Thalassemia
Interventions: DRUG: arginine butyrate|DRUG: epoetin alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Study of Sequential Administration of Oral 6-Thioguanine After Methotrexate in Patients With LCH
Status: COMPLETED
Conditions: Langerhans Cell Histiocytosis
Interventions: DRUG: Methotrexate|DRUG: 6-Thioguanine|DRUG: Leucovorin Calcium
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Long Alimentary Limb or Long Biliary Limb Roux-en-Y Gastric Bypass on Type 2 Diabetes Remission in Severely Obese Patients.
Status: RECRUITING
Conditions: Diabetes Mellitus Type 2 in Obese
Interventions: PROCEDURE: Standard Roux-en-Y gastric bypass|PROCEDURE: Long alimentary limb Roux-en-Y gastric bypass
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Gemigliptin Versus Glimepiride on Cardiac Diastolic Function in Patients With Type 2 Diabetes
Status: RECRUITING
Conditions: Ejection Fraction
Interventions: DRUG: Gemigliptin|DRUG: Glimepiride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bevacizumab Plus Capecitabin vs S-1 as Maintenance Treatment Following First-line Chemotherapy in the Patients With Advanced Colorectal Adenocarcinoma
Status: WITHDRAWN
Conditions: Colorectal Adenocarcinoma
Interventions: DRUG: S-1|DRUG: Bevacizumab|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cardiovascular Disease Risk of Awareness
Status: NOT_YET_RECRUITING
Conditions: Cardiovascular Diseases
Interventions: OTHER: Cardiovascular disease risk assessment|OTHER: Training and Consultancy|OTHER: Mobile Application|OTHER: Monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of TBI-1401(HF10) in Patients With Solid Tumors With Superficial Lesions
Status: COMPLETED
Conditions: Solid Tumor
Interventions: BIOLOGICAL: TBI-1401(HF10)|BIOLOGICAL: TBI-1401(HF10)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of HRV Biofeedback on Autonomic Function and Nicotine Withdrawal Symptoms and Dependence in Smoking Cessation Adults
Status: RECRUITING
Conditions: Heart Rate Variability, Biofeedback, Nicotine Dependence, Nicotine Withdrawal, Anxiety, Depression, Insomnia
Interventions: BEHAVIORAL: heart rate variability biofeedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Corneal Collagen Cross-Linking (CXL) Performed With "Epi-ON" Versus "Epi-OFF" in Eyes With Keratoconus and Other Corneal Ectatic Disorders
Status: NOT_YET_RECRUITING
Conditions: Keratoconus|Ectasia
Interventions: DRUG: Ricrolin+|DEVICE: VEGA UV-A system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Diet and Exercise Interventions in Peripheral Artery Disease
Status: NOT_YET_RECRUITING
Conditions: Claudication|Peripheral Artery Disease
Interventions: BEHAVIORAL: DASH Diet plus Home-Based Exercise|BEHAVIORAL: Home-Based Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of an Extract From the Wine Industry on Blood Pressure (HYPERGRAPES)
Status: COMPLETED
Conditions: Cardiovascular Diseases|Hypertension
Interventions: DIETARY_SUPPLEMENT: Extract from the wine industry|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Virtual Reality Technology in Ventrogluteal Injection Training
Status: COMPLETED
Conditions: Nursing Caries|Nursing Education
Interventions: BEHAVIORAL: Nursing students will be trained through virtual reality.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Novel BCMA-targeted CAR-T Cell Therapy for Multiple Myeloma
Status: RECRUITING
Conditions: Relapsed or Refractory Multiple Myeloma
Interventions: BIOLOGICAL: anti-BCMA CAR-T|DRUG: Cyclophosphamid|DRUG: Fludarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 3 Study to Evaluate Efficacy and Safety of AL001 in Frontotemporal Dementia (INFRONT-3)
Status: ACTIVE_NOT_RECRUITING
Conditions: Frontotemporal Dementia
Interventions: DRUG: AL001|DRUG: Placebo|DRUG: Open label - AL001
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cardiomyopathy in Steroid-resistant Nephrotic Syndrome: Impact of Focal Segmental Glomerulosclerosis
Status: TERMINATED
Conditions: Focal Segmental Glomerulosclerosis|Nephrotic Syndrome|Steroid Resistant Nephrotic Syndrome|Chronic Kidney Disease
Interventions: OTHER: Cardiovascular Assessment|OTHER: Renal Assessment|OTHER: Genetic Evaluation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Mind Our Heart Study
Status: NOT_YET_RECRUITING
Conditions: Peripheral Arterial Disease|Heart Failure|Myocardial Infarction|Atherosclerotic Cardiovascular Disease
Interventions: BEHAVIORAL: Mindfulness-based stress reduction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of Intestinal Secretion of Antibodies and Auto-antibodies Associated With Crohn's Disease
Status: COMPLETED
Conditions: Crohn's Disease
Interventions: OTHER: Blood sampling and biopsy|OTHER: Biopsy and blood sampling|OTHER: Biopsy and blood sampling
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: 18F-DCFPyL Positron Emission Tomography (PET) in Intermediate or High Risk Prostate Cancer
Status: TERMINATED
Conditions: Prostate Cancer
Interventions: DRUG: 18F-DCFPyL
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: TT52CAR19 Therapy for B-cell Acute Lymphoblastic Leukaemia (B-ALL)
Status: COMPLETED
Conditions: B Acute Lymphoblastic Leukemia
Interventions: DRUG: PBLTT52CAR19
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: VBI-S for the Treatment of Hypotension in Hypovolemic Septic Shock Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Septic Shock|Sepsis|Hypovolemia
Interventions: DRUG: VBI-S
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Betaquik as an Adjunct to Dietary Management of Epilepsy in Adults on the Modified Atkins Diet
Status: TERMINATED
Conditions: Epilepsy|Epilepsy Intractable|Seizures|Seizure Disorder|Ketogenic Dieting|Ketosis
Interventions: DIETARY_SUPPLEMENT: Betaquik
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety Study of Nivolumab in Combination With Ipilimumab in Participants With Advanced Non-small Cell Lung Cancer
Status: WITHDRAWN
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: Nivolumab|DRUG: Ipilimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Certolizumab Pegol for the Treatment of Patients With Active Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Certolizumab pegol (CZP)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Efficacy and Safety Study of Azilsartan Medoxomil Compared to Valsartan and Olmesartan in Participants With Essential Hypertension.
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Azilsartan medoxomil|DRUG: Azilsartan medoxomil|DRUG: Valsartan|DRUG: Olmesartan|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Optimum Brushing Force on Dental Plaque Removal and the Abrasive Effect of Brushing Force on Enamel Surface.
Status: COMPLETED
Conditions: the Optimum Brushing Force for Dental Plaque Removal and the Effect of Brushing Force on Enamel Characteristic
Interventions: PROCEDURE: brushing force
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate rhuFab V2 in Subjects With Minimally Classic or Occult Subfoveal Neovascular Macular Degeneration
Status: COMPLETED
Conditions: Macular Degeneration
Interventions: DRUG: rhuFab V2 (ranibizumab)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Everolimus in Patients With Pancreatic Neuroendocrine Tumors Metastatic to the Liver Previously Treated With Surgery
Status: TERMINATED
Conditions: Gastrinoma|Glucagonoma|Insulinoma|Liver Metastases|Pancreatic Polypeptide Tumor|Recurrent Islet Cell Carcinoma|Somatostatinoma
Interventions: DRUG: everolimus|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of the TRVD™ System in ADHF
Status: TERMINATED
Conditions: Acute Heart Failure|Congestive Heart Failure|Heart Failure, Congestive
Interventions: DEVICE: TRVD Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pelvic Girdle Pain in a Pregnant Population in Western Norway.
Status: COMPLETED
Conditions: Pelvic Girdle Pain
Interventions: OTHER: Chiropractic|OTHER: Conventional medical intervention|OTHER: Conventional and alternative intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Role of Dysbiosis of Gut Microbiota in the Pathogenesis of PCOS.
Status: UNKNOWN
Conditions: Polycystic Ovary Syndrome
Interventions: BEHAVIORAL: Lifestyle intervention|DRUG: Probiotic Agent|DRUG: Oral contraceptive
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: To Study the Impact of Stopping Therapy in Patients of CML With Molecular Remission
Status: UNKNOWN
Conditions: Chronic Myeloid Leukemia|Treatment Free Remission
Interventions: OTHER: Stopping the standard drug therpy|DIAGNOSTIC_TEST: Quantitative bcrabl recording every month for first 6 months
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Supreme-LMA for Neonatal Resuscitation: a Prospective, Randomized Single-center Study
Status: UNKNOWN
Conditions: Neonatal Resuscitation
Interventions: DEVICE: Supreme LMA|DEVICE: Facial mask
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ketoprofen Gel vs Placebo in Children With Ankle Sprain
Status: UNKNOWN
Conditions: Ankle Sprain
Interventions: DRUG: Ketoprofen|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: System Accuracy of the Blood Glucose Monitor for Personal Use BG-709b
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: DIAGNOSTIC_TEST: blood glucose measurement, blood glucose monitor for personal use|DIAGNOSTIC_TEST: blood glucose measurement, laboratory reference device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Early Nutritional Intervention in NPC Patients Undergoing Concurrent Chemoradiotherapy
Status: UNKNOWN
Conditions: Malnutrition|Nasopharyngeal Carcinoma
Interventions: DIETARY_SUPPLEMENT: oral nutritional supplements
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pancreatic Cancer Malnutrition and Pancreatic Exocrine Insufficiency in the Course of Chemotherapy in Unresectable Pancreatic Cancer
Status: UNKNOWN
Conditions: Pancreatic Cancer|Exocrine Pancreatic Insufficiency|Metastatic Pancreatic Cancer|Chemotherapy|Malnutrition|Locally Advanced Malignant Neoplasm
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study Comparing Effectiveness of Intraperitoneal Insulin Administration to Subcutaneous Insulin Administration
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: DRUG: Medtronic MiniMed Implantable Pump Human Recombinant Insulin|DEVICE: Medtronic MiniMed Implantable Pump System|DRUG: Aventis HOE21PH U400
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Carrelizumab (PD-1) Combined With Chemotherapy in Neoadjuvant Treatment of Locally Advanced Gastric Cancer
Status: UNKNOWN
Conditions: Locally Advanced Gastric Cancer
Interventions: DRUG: Camrelizumab + SOX (oxaliplatin + Teggio) /XELOX (oxaliplatin + capecitabine )
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Single Umbilical Artery Caused by Umbilical Artery Embolism on Pregnancy Outcome
Status: RECRUITING
Conditions: Umbilical Artery Embolism,Single Umbilical Artery,Pregnancy Outcome
Interventions: OTHER: collect information about all participants
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Attention Bias Modification Treatment (ABMT) for Anxiety Disorders in Youth
Status: COMPLETED
Conditions: Anxiety Disorders
Interventions: BEHAVIORAL: Attention Bias Modification treatment (ABMT)|BEHAVIORAL: Exposure only +ABMT|BEHAVIORAL: Attention training only +ABMT|BEHAVIORAL: Placebo group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ultrasound- Guided Continuous Retro Laminar Block Versus Continuous Erector Spinae Plane Block in Multiple Rib Fractures
Status: RECRUITING
Conditions: Retrolaminar Block|Erector Spinae Plane Block|Spirometry|Pain|Multiple Rib Fractures
Interventions: DRUG: Retrolaminar block group|DRUG: Erector spinae plane block group.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Synergistic Anti-plaque Activity of Salvadora Persica L. and Green Tea: A Clinical Comparative Study
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: OTHER: DTC1|OTHER: Oradex|OTHER: Distilled water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Simo Decoction and Gum Chewing for Bowel Activity
Status: COMPLETED
Conditions: Hepatocellular Carcinoma
Interventions: DIETARY_SUPPLEMENT: simo decoction|OTHER: gum chewing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Trial of KEEP-P, a Preventive Intervention for Foster Preschoolers (KEEP-P)
Status: COMPLETED
Conditions: Child Behavior
Interventions: BEHAVIORAL: KEEP-P|BEHAVIORAL: KEEP-P+
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A/H5N1 Vaccine in Healthy Children Aged 2-9 Years
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Influenza A/H5N1 Vaccine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Scent on Pregnancy Induced Nausea, Vomiting, and Quality of Life
Status: COMPLETED
Conditions: Morning Sickness|Pregnancy Early
Interventions: OTHER: Citrus-Based Aromatherapy|OTHER: Mint-Based Aromatherapy|OTHER: Spice-Scented Aromatherapy|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Efficacy of MBS2320 in Patients With Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: MBS2320|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of ORTD-1 in Patients Hospitalized With COVID-19 Related Pneumonia
Status: WITHDRAWN
Conditions: COVID-19
Interventions: DRUG: ORTD-1 low dose|DRUG: ORTD-1 mid dose|DRUG: ORTD-1 high dose|OTHER: Vehicle control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Subcuticular Continuous Suture Versus Skin Staples to Reduce Surgical Site Infections in Colorectal Surgery Patients
Status: UNKNOWN
Conditions: Surgical Wound Infections|Colorectal Surgery
Interventions: PROCEDURE: subcuticular suture|PROCEDURE: Skin staples
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effect of Abdominal Massage and Warm Application on Excretory Activity in Patients Undergoing Total Knee Replacement With Spinal Anesthesia
Status: RECRUITING
Conditions: Total Knee Replacement
Interventions: OTHER: abdominal massage andwarm application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Stem Cell Gene Therapy to Treat X-Linked Severe Combined Immunodeficiency (XSCID)
Status: COMPLETED
Conditions: Severe Combined Immunodeficiency
Interventions: DRUG: Gene-Transduced Autologous CD34+ Stem Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: The Effect of Vibrotactile Stimulation on Parkinson's Tremor
Status: COMPLETED
Conditions: Parkinson Disease|Tremor
Interventions: DEVICE: Vibrotactile stimulation at tremor frequency|DEVICE: Vibrotactile stimulation at tremor frequency*1.5|DEVICE: Vibrotactile stimulation at continuous stimulation|DEVICE: Vibrotactile stimulation 10% below and above step frequency
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Adipose Derived Stem Cells on Survival of Fat as Filler
Status: COMPLETED
Conditions: Skin Rejuvenation|Lipofilling
Interventions: PROCEDURE: lipofilling|PROCEDURE: lipofilling enriched with adipose tissue derived stem cells
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Psychobiological Responses to Choral Singing in Mentally Ill and Healthy Children and Adolescents
Status: UNKNOWN
Conditions: Stress
Interventions: BEHAVIORAL: "Amateur" Group Singing|BEHAVIORAL: "Professional" Group Singing
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Icotinib Versus First-line Chemotherapy Plus Maintenance Treatment in EGFR Positive Lung Adenocarcinoma Patients
Status: COMPLETED
Conditions: NSCLC
Interventions: DRUG: Icotinib|DRUG: Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Validating Incubators in the Lab: Optimizing Culture and Investigating blasTulation Yield
Status: RECRUITING
Conditions: Infertility
Interventions: OTHER: Benchtop Incubator|OTHER: Box Incubator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Clinical Use Cases Assessment of the Gabi System in Young Children With Underlying Medical Conditions (BRIDGE Study)
Status: COMPLETED
Conditions: Cardiac Disease|Respiratory Disease|Congenital Cardiac Defect|Cardiovascular Diseases|Chronic Respiratory Disease|Chronic Cardiopulmonary Disease|Premature Infant Disease
Interventions: DEVICE: Gabi System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: MVA85A Aerosol vs Intramuscular Vaccination in Adults With Latent Mycobacterium Tuberculosis (M. tb) Infection
Status: TERMINATED
Conditions: Tuberculosis
Interventions: BIOLOGICAL: Aerosol inhaled MVA85A|BIOLOGICAL: Intramuscular MVA85A|BIOLOGICAL: Intramuscular Saline placebo|BIOLOGICAL: Aerosol inhaled Saline placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Pulsed Electromagnetic Field (PEMF) Therapy for Post-Concussive Syndrome
Status: WITHDRAWN
Conditions: Post Concussive Syndrome|Concussion
Interventions: DEVICE: PEMF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Moderate Intensity Intermittent and Moderate Intensity Continuous Training on Hyperlipdemia
Status: COMPLETED
Conditions: Hyperlipidemias
Interventions: OTHER: Moderate intensity intermittent training|OTHER: Moderate intensity continuous training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of MRI Sequences for Ultra-rapid Acquisition of Bile Ducts Images
Status: TERMINATED
Conditions: Gallstone|Cholangitis|Cholangiocarcinoma|Pancreatitis|Pancreatic Ductal Adenocarcinoma
Interventions: OTHER: ultra-rapid acquisition of bile ducts images
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Bioequivalency Study of Amlodipine Besylate Tablets, 10 mg of Dr. Reddy's Under Fed Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Amlodipine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare the Efficacy and Safety of Levofloxacin in the Treatment of Children With Community-acquired Pneumonia in the Hospital or Outpatient Setting
Status: COMPLETED
Conditions: Pneumonia
Interventions: DRUG: Levofloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sildenafil Effect on Digital Ulcer Healing in sClerodErma SEDUCE STUDY
Status: COMPLETED
Conditions: Systemic Scleroderma
Interventions: DRUG: Sildenafil|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Is Cerazette Use Before Nexplanon Insertion Predictive for Bleeding Pattern?
Status: UNKNOWN
Conditions: Bleeding
Interventions: DRUG: Desogestrel 75 micrograms POP (Cerazette), Etonogestrel 68 mg implant (Nexplanon)|DRUG: Etonogestrel 68 mg subdermal implant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: N-of-1 Trial: Actionable Target Identification in Metastatic Cancer for Palliative Systemic Therapy
Status: COMPLETED
Conditions: Metastatic Cancer
Interventions: DRUG: EMA-approved ATI based targeted therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of an Investigational V212/Heat-Treated Varicella-Zoster Virus (VZV) Vaccine in Immunocompromised Adults (V212-002)
Status: COMPLETED
Conditions: Herpes Zoster|Herpes Zoster-related Complications
Interventions: BIOLOGICAL: V212|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Radiofrequency Catheter Ablation for Chronic Atrial Fibrillation
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: PROCEDURE: Radiofrequency catheter ablation|DRUG: Amiodarone and cardioversion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ACCELERATE Study - A Study of PEGASYS (Peginterferon Alfa-2a (40KD)) in Combination With COPEGUS (Ribavirin) in Interferon-Naive Patients With Chronic Hepatitis C (CHC) Infection.
Status: COMPLETED
Conditions: Hepatitis C, Chronic
Interventions: DRUG: Copegus|DRUG: Copegus|DRUG: peginterferon alfa-2a [Pegasys]|DRUG: peginterferon alfa-2a [Pegasys]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective, Open Label Study to Assess 24hs IOP Recorded With Triggerfish® in Patients With OAG Before and After DSCI
Status: TERMINATED
Conditions: Open Angle Glaucoma
Interventions: DEVICE: contact lens sensor (CLS) SENSIMED Triggerfish®
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Observational Study on Safety and Efficacy of NovoSeven® in Subjects With Congenital FVII Deficiency
Status: COMPLETED
Conditions: Congenital Bleeding Disorder|Congenital FVII Deficiency
Interventions: DRUG: activated recombinant human factor VII
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Nursing Care on Circadian Rhythm
Status: COMPLETED
Conditions: Circadian Rhythm|Chronobiology Disorders|Biological Clock Disturbance|Nursing Care|Sleep Quality
Interventions: OTHER: sleeping glasses and earplug
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Phase I Study of XJ101 in Chinese Healthy Subjects
Status: ACTIVE_NOT_RECRUITING
Conditions: Staphylococcus Aureus Bloodstream Infection
Interventions: DRUG: XJ101 for Injection|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Shared Decision Making on Radiation Dose for Lung Malignancies
Status: RECRUITING
Conditions: Decision Making, Shared|Stereotactic Body Radiation Therapy|Lung Cancer, Non-small Cell|Radiation Toxicity|Lung Metastases
Interventions: BEHAVIORAL: A Patient Decision Aid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study of Favezelimab Coformulated With Pembrolizumab (MK-4280A) in Participants With Selected Solid Tumors (MK-4280A-010)
Status: RECRUITING
Conditions: Solid Tumor|Cutaneous Squamous Cell Carcinoma|Endometrial Cancer
Interventions: BIOLOGICAL: favezelimab/pembrolizumab|BIOLOGICAL: pembrolizumab|DRUG: lenvatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hepatic Arterial Infusion (HAI) of Abraxane
Status: COMPLETED
Conditions: Liver Cancer|Advanced Cancers|Solid Tumors
Interventions: DRUG: HAI Abraxane|PROCEDURE: Hepatic Artery Catheter|DRUG: IV Abraxane
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mouth-to-mouth Ventilation Efficiency Through Breathable Self-sterilizing Respirator During BLS in COVID-19 Pandemic (MOVE)
Status: WITHDRAWN
Conditions: Basic Life Support Ventilation
Interventions: PROCEDURE: Mout-to-mouth ventilation|PROCEDURE: Mout-to-mouth ventilation with quantitative analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Eplerenone and Atorvastatin on Markers of Collagen Turnover in Diastolic Heart Failure
Status: COMPLETED
Conditions: Diastolic Heart Failure
Interventions: DRUG: Eplerenone|OTHER: No additional treatment|DRUG: Atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Wide Area Circular Ablation Versus Extra-wide Area Circular Ablation in Persistent Atrial Fibrillation
Status: UNKNOWN
Conditions: Atrial Fibrillation
Interventions: PROCEDURE: Ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of an Implementation Strategy of mHealth Intervention to Promote Healthy Lifestyles (E-VIDAPP Pilot Study)
Status: COMPLETED
Conditions: Healthy Lifestyle|Nursing
Interventions: DEVICE: Evident 3|OTHER: Implementation strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Immunogenicity and Safety of mRNA-1283 COVID-19 Vaccine Boosters
Status: COMPLETED
Conditions: SARS-CoV-2
Interventions: BIOLOGICAL: mRNA-1283|BIOLOGICAL: mRNA-1283.211|BIOLOGICAL: mRNA-1273|BIOLOGICAL: mRNA-1283.529
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Comparison of the Accurate Diagnosis of the Horizontal & Vertical Bitewing Images
Status: UNKNOWN
Conditions: Periodontal Diseases|Dental Caries
Interventions: RADIATION: Bitewing X ray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: A RTC to Examine the Effectiveness of 400 mg of Oral Zinc Gluconate as Adjunctive Therapy for Ano-genital Warts
Status: TERMINATED
Conditions: Genital Warts|HPV
Interventions: DRUG: Oral Zinc|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Comparison Study of Oxybutynin and Botulinum Toxin for Neurogenic Detrusor Overactivity
Status: COMPLETED
Conditions: Spinal Cord Injury
Interventions: DRUG: Oxybutynin|DRUG: Botulinum toxin A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neo-Adjuvant Chemotherapy (TAC) With or Without Zoledronic Acid in Treating HER2-negative Breast Cancer Patients
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: cyclophosphamide|DRUG: docetaxel|DRUG: doxorubicin hydrochloride|DRUG: zoledronic acid|PROCEDURE: neoadjuvant therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endoscopic Pilonidal Sinus Treatment (EPSIT) Versus Sinus Laser Closure (SiLaC) Versus Lay Open Technique
Status: UNKNOWN
Conditions: Pilonidal Sinus
Interventions: PROCEDURE: Endoscopic Pilonidal sinus treatment (EPSIT) versus Sinus Laser Closure (SiLaC) versus lay open technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: LC-MS/MS Based Method Development for the Monitoring of Antibiotic Concentrations in Sputum of Cystic Fibrosis Patients
Status: TERMINATED
Conditions: Cystic Fibrosis
Interventions: DRUG: Piperacillin-tazobactam combination product|DRUG: Meropenem|DRUG: Ceftazidime
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Adapting Food Culture to the Mediterranean Pattern for International Students in Italy
Status: RECRUITING
Conditions: Physical Inactivity|Eating Disorders|Eating Habit|Diet, Healthy|Diet Habit
Interventions: BEHAVIORAL: Food education
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Early Hydrogen-Oxygen Gas Mixture Inhalation in Patients With Aneurysmal Subarachnoid Hemorrhage (HOMA)
Status: UNKNOWN
Conditions: Aneurysmal Subarachnoid Hemorrhage
Interventions: DEVICE: Hydrogen Oxygen Generator with Nebulizer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of Repotrectinib Versus Crizotinib in Participants With Locally Advanced or Metastatic Tyrosine Kinase Inhibitor (TKI)-naïve ROS1-positive Non-Small Cell Lung Cancer (NSCLC) (TRIDENT-3)
Status: RECRUITING
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: Repotrectinib|DRUG: Crizotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Value of 25 mcg Cortrosyn Stimulation Test
Status: COMPLETED
Conditions: Adrenal Insufficiency
Interventions: PROCEDURE: 1 ug ACTH stimulation test|PROCEDURE: 250 ug ACTH stimulation test|PROCEDURE: 25 ug Cortrosyn stimulation test|PROCEDURE: Insulin tolerance test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Pilot Study of Transcoronary Myocardial Cooling
Status: COMPLETED
Conditions: Acute Myocardial Infarction
Interventions: OTHER: Cohort A - Room temperature coronary perfusate|OTHER: Cohort B - Cooled coronary perfusate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HEpatic Regeneration With COupled Plasma Filtration and Adsorption for Liver Extracorporeal Detoxification
Status: COMPLETED
Conditions: Liver Failure, Acute|Liver Failure, Acute on Chronic
Interventions: DEVICE: Coupled plasma filtration and adsorption (CPFA)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE