pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Changes in Plantar Preassures and Ankle Range of Motion After the Technique of Neuromeningeal Mobilization
Status: COMPLETED
Conditions: Postural Balance|Rehabilitation|Foot|Therapy
Interventions: OTHER: Neural mobilization of the deep peroneal, posterior tibial and medial medial and lateral dorsocutaneous nerves.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of a Previous CS on the Ongoing Pregnancy Rate in Single Euploid Frozen Embryo Transfer (ET)
Status: RECRUITING
Conditions: Infertility|Implantation
Interventions: DIAGNOSTIC_TEST: Ultrasound between 6+0 and 6+7 weeks of pregnancy - With Isthmocele|DIAGNOSTIC_TEST: Ultrasound between 6+0 and 6+7 weeks of pregnancy - Without Isthmocele|DIAGNOSTIC_TEST: Ultrasound between 6+0 and 6+7 weeks of pregnancy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Web-based Mindfulness-based Stress Reduction Program on Pregnant Women
Status: COMPLETED
Conditions: Anxiety|Pregnancy Related
Interventions: BEHAVIORAL: Mindfullness Based Stress Reduction (MBSR) intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Short Course Primaquine for the Radical Cure of P. Vivax Malaria - Indonesia
Status: RECRUITING
Conditions: Vivax Malaria|G6PD Deficiency
Interventions: COMBINATION_PRODUCT: Revised case management package
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Imipenem/Cilastatin/Relebactam (IMI/REL) in Treatment of CRE Infections
Status: WITHDRAWN
Conditions: Carbapenem-Resistant Enterobacteriaceae Infection|KPC|Gram-Negative Bacterial Infections|Antibiotic Resistant Infection
Interventions: DRUG: Imipenem+Relebactam
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Prospective European Post-Market Clinical Evaluation of the CuraSeal Percutaneous Intraluminal Closure System for Anorectal Fistulas
Status: UNKNOWN
Conditions: Anal Fistulas|Rectal Fistulas
Interventions: DEVICE: PICS-AF Device|DEVICE: Historical Controls Treated with Commercially Available Fistula Plugs
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Tolvaptan on Renal Plasma Flow (RPF) and Glomerular Filtration Rate (GFR) in ADPKD
Status: COMPLETED
Conditions: Polycystic Kidney, Autosomal Dominant
Interventions: DRUG: Tolvaptan|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Inflammation Reduction by TREhalose AdminisTration
Status: UNKNOWN
Conditions: Acute Coronary Syndrome
Interventions: DRUG: Trehalose|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ex Vivo Effect of Surfactant Protein D on Pulmonary Cells in Patients With Asthma and Pilot Study to Assess Local Inflammation Induced by Segmental Allergen Challenge by Magnetic Resonance Imaging
Status: COMPLETED
Conditions: Mild Intermittent Asthma (Gina 1)
Interventions: OTHER: Bronchoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pramipexole and Bromocriptine on Nonmotor Symptoms of Early Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DRUG: pramipexole|DRUG: Bromocriptine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The LC Bead Trial; Transarterial Chemoembolization of Hepatocellular Carcinoma (HCC)With a Drug-eluting Bead
Status: TERMINATED
Conditions: Hepatocellular Carcinoma
Interventions: DEVICE: transarterial chemoembolization using a drug-eluting bead
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Using Technology to Optimize Collaborative Care Management of Depression in Urban and Rural Cancer Centers, SCOPE
Status: RECRUITING
Conditions: Depression|Hematopoietic and Lymphoid Cell Neoplasm|Malignant Solid Neoplasm
Interventions: OTHER: Collaborative care|OTHER: Interview or Focus Group|OTHER: Media/technology Intervention with collaborative care|OTHER: Survey Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Chronic Study on Body Composition, Training, Performance, and Recovery
Status: COMPLETED
Conditions: Damage Muscle|Body Weight Changes|Performance Enhancing Product Use
Interventions: DIETARY_SUPPLEMENT: Pre-workout plus and Protein recovery plus|OTHER: Placebo|OTHER: 6-week resistance training program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: The Role of Vitamin D, A, and Beta Carotene in Tuberculosis Patients With Vitamin D Receptor Gene Polymorphism
Status: COMPLETED
Conditions: Tuberculosis
Interventions: DIETARY_SUPPLEMENT: vitamin D 1000 IU and A 6000 IU supplementation and nutritional counseling|OTHER: nutritional Counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Role of Acupuncture-induced Exosome in Treating Post-stroke Dementia
Status: RECRUITING
Conditions: Exosome|Post-stroke Dementia|Acupuncture
Interventions: DEVICE: Acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Whole Exome Sequencing in Bicuspid Aortic Valve Patients
Status: UNKNOWN
Conditions: Bicuspid Aortic Valve
Interventions: BIOLOGICAL: Extra blood draw samples|BIOLOGICAL: additional tissue samples
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Etiologic Mechanisms, Myocardial Changes and Prognosis of Patients With MINOCA
Status: UNKNOWN
Conditions: Myocardial Infarction With Nonobstructive Coronary Arteries
Interventions: OTHER: extended clinical, laboratory and instrumental examination; treatment options comparison
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Effect of Pelvic Floor Muscle Exercises on the Inferior Vena Cava
Status: COMPLETED
Conditions: Supine Hypotensive Syndrome
Interventions: OTHER: pelvic floor muscle exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study on the Impact of Education Website on the Quality of Outpatient Bowel Preparation for Colonoscopy
Status: COMPLETED
Conditions: Colon Cancer
Interventions: DEVICE: Aiddly (Web Site)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Keiki (Pediatric) Produce Prescription (KPRx) Program Hawaii
Status: RECRUITING
Conditions: Malnutrition, Child|Obesity|Food Selection|Nutrition Poor
Interventions: BEHAVIORAL: Produce Voucher|BEHAVIORAL: Wait-List Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Evaluate the Efficacy and Safety of D064 and D702 Combination Therapy
Status: COMPLETED
Conditions: Essential Hypertension
Interventions: DRUG: D064, D702, placebo of D660|DRUG: D660, placebo of D064, placebo of D702
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Improvement of Knowledge About the Arthrogenic Muscle Inhibition in the Aftermath of Knee Trauma.
Status: COMPLETED
Conditions: Anterior Cruciate Ligament Rupture
Interventions: DIAGNOSTIC_TEST: functional brain MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Trial of DFP-10917 vs Non-Intensive or Intensive Reinduction for AML Patients in 2nd/3rd/4th Salvage
Status: RECRUITING
Conditions: Leukemia, Myeloid, Acute
Interventions: DRUG: DFP-10917|DRUG: Cytarabine|DRUG: Azacitidine|DRUG: Decitabine|DRUG: Mitoxantrone|DRUG: Etoposide|DRUG: Fludarabine|DRUG: Idarubicin|DRUG: Venetoclax|DRUG: Cladribine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Muscle Function After Childbirth
Status: RECRUITING
Conditions: Postpartum|Muscle Fatigue|Force Steadiness|Nulligravid|Muscle Weakness
Interventions: DIAGNOSTIC_TEST: Active Straight Leg Raise Test|OTHER: Active Straight Leg Raise Fatigue Task|OTHER: Lower Extremity Strength Testing|DIAGNOSTIC_TEST: Ultrasound imaging of abdominal wall
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Adjunctive Neuromuscular Electrical Stimulation for the Rehabilitation of Swallowing
Status: COMPLETED
Conditions: Dysphagia
Interventions: BEHAVIORAL: swallowing therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hybrid Functional Electrical Stimulation Exercise to Prevent Cardiopulmonary Declines in High-level Spinal Cord Injury
Status: RECRUITING
Conditions: Spinal Cord Injuries
Interventions: DRUG: Buspirone Hydrochloride|DRUG: Buspirone placebo|DEVICE: Noninvasive Ventilation (NIV)|DEVICE: Sham Non-invasive ventilation (NIV)|OTHER: Functional Electrical Stimulation Row Training (FESRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Daratumumab Plus Ibrutinib in Patients With Waldenstrӧm's Macroglobulinemia
Status: TERMINATED
Conditions: Waldenstrom Macroglobulinemia|Waldenstrom's Disease|Waldenström; Hypergammaglobulinemia|Waldenstrom's Macroglobulinemia Recurrent|Waldenstrom's Macroglobulinemia of Lymph Nodes|Waldenstrom's Macroglobulinaemia, Without Mention of Remission|Waldenstrom's Macroglobulinemia Refractory
Interventions: DRUG: Ibrutinib|DRUG: Daratumumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of RL- vs LL-starting Position in Unsedated Water Immersion Colonoscopy
Status: UNKNOWN
Conditions: Water Immersion Method Colonoscopy in Unsedated Patients
Interventions: PROCEDURE: modified- WIM colonoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Estrogen and Serotonin on Changing Brain Chemistry
Status: COMPLETED
Conditions: Menopause
Interventions: DRUG: estrogen patch|DRUG: Amino acids|DRUG: Placebo Patch|DRUG: Placebo pills
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing Rehabilitation Programs for Patellofemoral Pain Syndrome
Status: COMPLETED
Conditions: Patellofemoral Pain Syndrome
Interventions: OTHER: Hip Progressive Resistive Exercise|OTHER: Quad Progressive Resistive Exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Combination Clinical Study of PLX3397 and Pembrolizumab To Treat Advanced Melanoma and Other Solid Tumors
Status: TERMINATED
Conditions: Melanoma|Non-small Cell Lung Cancer|Squamous Cell Carcinoma of the Head and Neck|Gastrointestinal Stromal Tumor (GIST)|Ovarian Cancer
Interventions: DRUG: PLX3397|BIOLOGICAL: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 64Cu-LLP2A for Imaging Multiple Myeloma
Status: RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: 64Cu-LLP2A|DEVICE: PET/MR|PROCEDURE: Blood samples for serum stability|PROCEDURE: Blood samples for metabolite analysis|PROCEDURE: Urine sample|PROCEDURE: Tumor biopsy|PROCEDURE: Electrocardiogram|DEVICE: PET/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparison of Two Robotic-Assisted Total Knee Arthroplasty Systems
Status: NOT_YET_RECRUITING
Conditions: Knee Osteoarthritis|Knee Arthritis|Knee Disease
Interventions: DEVICE: Stryker Triathlon with MAKO Robotic-Arm|DEVICE: DePuy Attune with VELYS Robotic-Assistance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pembrolizumab in Relapsed or Refractory Extranodal NK/T- Cell Lymphoma, Nasal Type and EBV-associated Diffuse Large B Cell Lymphomas
Status: WITHDRAWN
Conditions: Lymphoma
Interventions: DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Imaging Study to Investigate the Distribution of GW842166X in the Brain.
Status: COMPLETED
Conditions: Pain, Inflammatory
Interventions: DRUG: GW842166X|DRUG: [carbonyl-^11C]GW842166
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Retroperitoneal Packing or Angioembolization for Hemorrhage Control of Pelvic Fractures
Status: COMPLETED
Conditions: Shock, Hemorrhagic|Fractures, Bone|Multiple Trauma
Interventions: PROCEDURE: PACKING|PROCEDURE: ANGIO
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Study of Allo LMI Vaccine With IL-2 for Stable Metastatic Breast Ca
Status: TERMINATED
Conditions: Breast Cancer
Interventions: BIOLOGICAL: allogeneic large multivalent immunogen breast cancer vaccine|BIOLOGICAL: aldesleukin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Behavioral Economics in Repeat SARS-CoV-2 (COVID-19) Antibody Testing in Disadvantaged Communities
Status: COMPLETED
Conditions: SARS-CoV-2
Interventions: BEHAVIORAL: Family Risk Messaging|BEHAVIORAL: Personal Risk Messaging|BEHAVIORAL: Loss Protection|BEHAVIORAL: Lottery Incentive
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Phase II/III Randomized Clinical Trial of Booster Dose of COVID-19 (Recombinant, Inactivated) Vaccine
Status: ACTIVE_NOT_RECRUITING
Conditions: Coronavirus Infections|Healthy
Interventions: BIOLOGICAL: NDV-HXP-S 10μg|BIOLOGICAL: BNT162b2 30μg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: 30-Day Cardiac Event Monitor Belt for Recording Atrial Fibrillation After a Cerebral Ischemic Event
Status: UNKNOWN
Conditions: Stroke|Transient Ischemic Attack|Atrial Fibrillation|Atrial Flutter
Interventions: DEVICE: a 30-day ambulatory cardiac event monitor|DEVICE: 24-hour Holter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: KD6001 in Combination With Anti-PD-1 Antibody±Bevacizumab in Patients With Advanced HCC and Other Solid Tumors
Status: NOT_YET_RECRUITING
Conditions: Advanced HCC|Other Solid Tumors
Interventions: DRUG: KD6001|DRUG: Tislelizumab|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Satiety Response of Four Dietary Fibers
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Control|DIETARY_SUPPLEMENT: Soluble corn fiber|DIETARY_SUPPLEMENT: Resistant starch|DIETARY_SUPPLEMENT: Fructooligosaccharide|DIETARY_SUPPLEMENT: Inulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of a Supervised Rehabilitation Program on Disease Severity in Spastic Ataxias
Status: RECRUITING
Conditions: Autosomal Recessive Spastic Ataxia of Charlevoix-Saguenay|Spastic Paraplegia 7
Interventions: PROCEDURE: IMPACT - rehabIlitation prograM for sPAstiC aTaxias
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of Bi-Level Positive Airway Pressure (BIPAP) Versus Non Invasive Positive Pressure Ventilation (NIPPV) for Neonatal Respiratory Failure
Status: UNKNOWN
Conditions: Neonatal Respiratory Failure
Interventions: PROCEDURE: Nasal Intermittent Positive Pressure Ventilation (NIPPV)|PROCEDURE: Bi-Level Positive Airway Pressure (BIPAP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: The VIGOR Study - Virtual Immersive Gaming to Optimize Recovery in Low Back Pain
Status: COMPLETED
Conditions: Chronic Low Back Pain|Fear of Pain|Fear of Injury
Interventions: BEHAVIORAL: Experimental Group 1|BEHAVIORAL: Experimental Group 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Safety, Efficacy and PK of Multiple Doses of QL-007 in Chronic Hepatitis B Patients in CHINA
Status: UNKNOWN
Conditions: Chronic Hepatitis b
Interventions: DRUG: QL-007 tablet|DRUG: TDF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Ticagrelor vs. Placebo in the Reduction of Vaso-occlusive Crises in Pediatric Patients With Sickle Cell Disease
Status: TERMINATED
Conditions: Sickle Cell Disease
Interventions: DRUG: Ticagrelor|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Stereotactic Body Radiotherapy (SBRT) and Surgical Stabilization for People With Cancer That Has Spread to the Bone
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Cancer
Interventions: RADIATION: Preoperative Stereotactic Body Radiotherapy (SBRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: AWARENESS Trial (AWARENESS) of Storytelling Through Music in Healthcare Workers
Status: ENROLLING_BY_INVITATION
Conditions: Stress|Post Traumatic Stress Disorder|Work Related Stress
Interventions: BEHAVIORAL: Storytelling Through Music (STM)|BEHAVIORAL: Wait List / Storytelling Through Music-Hybrid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Neoadjuvant Therapy for Esophageal Cancer and Cardiopulmonary Physiology
Status: COMPLETED
Conditions: Esophageal Cancer|Radiation Pneumonitis|Pulmonary Fibrosis|Respiratory Failure|Pneumonia|Surgery|Chemotherapy Effect|Radiation Fibrosis|Radiation Toxicity|Adenocarcinoma|Squamous Cell Carcinoma
Interventions: PROCEDURE: Esophagectomy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Allogeneic Hematopoietic Cell Transplantation for Peripheral T Cell Lymphoma
Status: RECRUITING
Conditions: Peripheral T-cell Lymphomas|Lymphoproliferative Disorders|Immune System Diseases
Interventions: DRUG: ATL-RIC|DRUG: mRIC|PROCEDURE: allo HCT|DRUG: RIC|DRUG: GVHD prophylaxis|DRUG: IOC
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Fractional Er:YAG Laser in Lupus Erythematosus Scars
Status: WITHDRAWN
Conditions: Lupus Erythematosus, Cutaneous
Interventions: DEVICE: Er:YAG laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Envafolimab Combined With Recombinant Human Endostatin and First-line Chemotherapy Treat of Advanced Mucosal Melanoma
Status: NOT_YET_RECRUITING
Conditions: Advanced Mucosal Melanoma
Interventions: DRUG: Envafolimab combined with recombinant human endostatin and first-line chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ZD6474 (ZACTIMA™) Phase III Study in EGFR Failures
Status: COMPLETED
Conditions: Non-Small-Cell Lung Carcinoma
Interventions: DRUG: ZD6474 (vandetanib)|OTHER: Best Supportive Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Valiant Mona LSA Thoracic Stent Graft System in Thoracic Aortic Aneurysms and Chronic Dissections
Status: WITHDRAWN
Conditions: Aortic Aneurysm, Thoracic
Interventions: DEVICE: Valiant Mona LSA Thoracic Stent Graft System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Treatment of Upper Trapezius Muscle Myofascial Pain Syndrome
Status: RECRUITING
Conditions: Myofascial Pain Syndrome
Interventions: OTHER: Deep Fascia Dry needling Technique|OTHER: Intramuscular Trigger Point Dry Needling Technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Examining Mu Opioid Mechanisms of Ketamine's Rapid Effects in OCD (MKET2)
Status: RECRUITING
Conditions: Obsessive-Compulsive Disorder
Interventions: DRUG: Ketamine|DRUG: Naltrexone Pill|OTHER: Placebo pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Computed Tomogram Myocardial Thickness Map Guided pulmOnary Vein iSolaTion vs. Empirical Pulmonary Vein Isolation in Cryoballoon Ablation for Paroxysmal Atrial Fibrillation (UTMOST AF II)
Status: RECRUITING
Conditions: Paroxysmal Atrial Fibrillation
Interventions: PROCEDURE: Unipolar voltage subtraction map guided PV isolation group|PROCEDURE: CT myocardial thickness map guided PV isolation group|PROCEDURE: Empirical PV isolation group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Idursulfase-beta (GC1111) in Hunter Syndrome
Status: UNKNOWN
Conditions: Mucopolysaccharidosis II
Interventions: BIOLOGICAL: idursulfase beta|BIOLOGICAL: idursulfase
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Intraosseous Anesthesia Osteocentral With Electronic Assistance to Injection With Conventional Anesthesia
Status: COMPLETED
Conditions: Pain
Interventions: DEVICE: sleeper one|DEVICE: conventional technis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Inhalation of KELEA Excellerated Water in Covid-19 Infected Individuals
Status: ACTIVE_NOT_RECRUITING
Conditions: Covid19
Interventions: DEVICE: KELEA Excellerated Water|DEVICE: Water Without an Elevated Level of KELEA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Gene Therapy for Acute Myocardial Infarction in Korea
Status: UNKNOWN
Conditions: Ischemic Heart Disease|Acute Myocardial Infarction
Interventions: BIOLOGICAL: Stage 1-Low dose VM202RY|BIOLOGICAL: Stage 1-Middle dose VM202RY|BIOLOGICAL: Stage 1-High dose VM202RY|DRUG: Stage 2-Placebo|BIOLOGICAL: Stage 2-Low dose VM202RY|BIOLOGICAL: Stage 2-High dose VM202RY|DEVICE: C-Cathez® Catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pulsed-field Ablation for Patients With Asymptomatic Non-paroxysmal Atrial Fibrillation
Status: NOT_YET_RECRUITING
Conditions: Atrial Fibrillation|Pulsed-field Ablation|Functional Exercise Testing
Interventions: PROCEDURE: Catheter ablation for atrial fibrillation using pulsed-field energy|PROCEDURE: Conservative arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Blood Loss Following Total Hip Arthroplasty With the Use of Three Thromboprophylactic Regimes: Dabigatran, Enoxaparin and Rivaroxaban.
Status: UNKNOWN
Conditions: Hip Osteoarthritis|Blood Loss
Interventions: DRUG: Enoxaparin|DRUG: rivaroxaban|DRUG: dabigatran
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Cosopt Versus Combigan on Retinal Vascular Autoregulation in Primary Open Angle Glaucoma (POAG)
Status: COMPLETED
Conditions: Glaucoma
Interventions: DRUG: Dorzolamide 2%-timolol 0.5%|DRUG: Brimonidine 0.2%-0.5% timolol 0.5
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of Pembrolizumab (MK-3475) in Participants With Advanced Urothelial Cancer (MK-3475-052/KEYNOTE-052)
Status: COMPLETED
Conditions: Urothelial Cancer
Interventions: BIOLOGICAL: pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Analgesic Efficacy of AZD2423 Compared With Placebo After 28 Days Treatment in Patients With Posttraumatic Neuralgia..
Status: COMPLETED
Conditions: Nerve Pain
Interventions: DRUG: AZD2423|DRUG: AZD2423|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Glucose and Fructose Stimulated Brain Activity in Obese Subjects Before and After Bariatric Surgery
Status: COMPLETED
Conditions: Exploratory Behavior
Interventions: DIETARY_SUPPLEMENT: Tap water|DIETARY_SUPPLEMENT: Glucose|DIETARY_SUPPLEMENT: Fructose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Raman Spectroscopy and Skin Cancer
Status: NOT_YET_RECRUITING
Conditions: Skin Cancer|Basal Cell Carcinoma|Squamous Cell Carcinoma
Interventions: DEVICE: Raman Spectroscopy handheld probe (EmVision, FL, USA)|DEVICE: Raman Spectroscopy laser source (Hubner Photonics Inc, CA, USA)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Polymorphism of Oxidative Stress Genes in the Pathogenesis and Antioxidant Prevention of Contrast Induced Nephropathy
Status: COMPLETED
Conditions: Nephropathy|Oxidative Stress
Interventions: DRUG: Glutathione|DRUG: saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Pilot Trial to Test the Feasibility of Utilizing Home Blood Pressure Monitoring to Optimize the Administration of Midodrine Among Decompensated Cirrhosis Patients
Status: RECRUITING
Conditions: Cirrhosis, Liver|Portal Hypertension|Ascites Hepatic
Interventions: DEVICE: Withings Home Blood Pressure Device and Scale|OTHER: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Dietary Modifications Effect on Continuous LCIG Infusion Outcomes in Patients With Advanced Parkinson&Apos;s Disease
Status: UNKNOWN
Conditions: Parkinson Disease
Interventions: DIETARY_SUPPLEMENT: different diets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Diamel in the Treatment of Polycystic Ovary Syndrome
Status: COMPLETED
Conditions: Polycystic Ovary Syndrome
Interventions: DIETARY_SUPPLEMENT: Diamel|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of Solifenacin Versus Placebo Plus Pessary for Women With Vaginal Prolapse
Status: TERMINATED
Conditions: Pelvic Organ Prolapse
Interventions: DRUG: Solifenacin|DRUG: Placebo|DEVICE: Ring pessary with support, Cooper Surgical, Trumbell, CT Ref # MXPRS03 non-latex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Test How Well Different Doses of BI 3706674 Are Tolerated by People With Advanced Cancer in the Stomach and Oesophagus
Status: RECRUITING
Conditions: Solid Tumor, KRAS Mutation
Interventions: DRUG: BI 3706674
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Open Label Trial to Determine Safety & Efficacy of Tisagenlecleucel in Pediatric Non-Hodgkin Lymphoma Patients
Status: COMPLETED
Conditions: Non-Hodgkin Lymphoma
Interventions: BIOLOGICAL: Tisagenlecleucel|DRUG: lymphodepleting chemotherapy|DRUG: Bridging Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study on Safety and Effectiveness of Three Doses of Argatroban as Anticoagulant in Percutaneous Coronary Intervention (PCI)
Status: COMPLETED
Conditions: Coronary Artery Disease|Angina, Unstable
Interventions: DRUG: Argatroban|DRUG: Argatroban|DRUG: Argatroban|DRUG: Heparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Severe Illness TrAnslational BioLogy InformaticS in Humans
Status: NOT_YET_RECRUITING
Conditions: Sepsis|ARDS|Critical Illness|Neurocognitive Dysfunction|Shock, Septic|Ventilator Associated Pneumonia|Immune Suppression|Inflammation|SIRS
Interventions: PROCEDURE: Phelebotomy|PROCEDURE: Broncheoalveolar Lavage|PROCEDURE: Tracheal Aspirate|PROCEDURE: Rectal Swab
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Different Physical Therapy Programs on Pulmonary Rehabilitation in Patients With Lung Cancer
Status: UNKNOWN
Conditions: Rehabilitation
Interventions: BEHAVIORAL: ACBT training|DEVICE: acpella®PEP|DEVICE: EDP-type II external diaphragm pacemaker
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of BL-M14D1 in Patients With Locally Advanced or Metastatic Small Cell Lung Cancer, Neuroendocrine Tumors and Other Solid Tumors
Status: RECRUITING
Conditions: Small Cell Lung Cancer|Neuroendocrine Tumors
Interventions: DRUG: BL-M14D1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study on Safety, Tolerability and Pharmacokinetics of RO5303253 in Healthy Volunteers and Patients With Chronic Hepatitis C Genotype 1
Status: COMPLETED
Conditions: Hepatitis C, Chronic, Healthy Volunteer
Interventions: DRUG: Placebo|DRUG: RO5303253|DRUG: RO5303253|DRUG: RO5303253
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Clinical Study of ALT-P7 to Determine Safety, Tolerability and Pharmacokinetics in Breast Cancer Patients
Status: COMPLETED
Conditions: HER2-positive Breast Cancer
Interventions: BIOLOGICAL: ALT-P7 (HM2-MMAE)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Diagnostic Relevance of Laser Confocal Microscopy for the Screening of Upper Urinary Tract Tumors
Status: COMPLETED
Conditions: Hematuria|Nephrolithiasis|Cancer of Urinary Tract|Ureteropelvic Junction Obstruction
Interventions: DEVICE: Laser confocal microscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Closure of Anastomotic Leaks in the Stomach and Esophagus by Endoscopic Suturing
Status: UNKNOWN
Conditions: Postoperative|Anastomosis, Surgical
Interventions: DEVICE: endoscopic suturing
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Calcium Polycarbophil on Type II Diabetes Mellitus Control: a Randomized Double-blind Study
Status: COMPLETED
Conditions: Diabetes Mellitus Type II
Interventions: DRUG: Placebo|DRUG: Calcium polycarbophil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Vitamin D on Renal Blood Flow, Proteinuria and Inflammation in Patients With Chronic Kidney Disease
Status: WITHDRAWN
Conditions: Chronic Kidney Disease|Secondary Hyperparathyroidism
Interventions: DRUG: Contrast Enhanced Ultrasonography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: No Monitoring of Post-filter Ionized Calcium in Regional Citrate Anticoagulation
Status: COMPLETED
Conditions: Regional Citrate Anticoagulation|Ionized Calcium|Continuous Renal Replacement Therapy
Interventions: OTHER: Regional citrate anticoagulation|DRUG: Vasopressor|DRUG: Antibiotic|DEVICE: Dialysis with continuous renal replacement therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Quality of Life of Patients With Acute Myelogenous Leukemia (AML) or Myelodysplastic Syndrome (MDS)
Status: COMPLETED
Conditions: Acute Myelogenous Leukemia|Myelodysplastic Syndrome
Interventions: BEHAVIORAL: Questionnaire|BEHAVIORAL: Neurocognitive Testing
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: DU-176b Phase 2 Dose Finding Study in Subjects With Non-valvular Atrial Fibrillation
Status: COMPLETED
Conditions: Atrial Fibrillation|Stroke
Interventions: DRUG: DU-176b tablets|DRUG: DU-176b tablets|DRUG: Warfarin tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: An Observational Study in Patients Using NovoMix® 30 or Levemir® for Treatment of Type 1 or Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 1|Diabetes Mellitus, Type 2
Interventions: DRUG: biphasic insulin aspart 30|DRUG: insulin detemir
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety, Efficacy and Pharmacokinetics of ALD403
Status: COMPLETED
Conditions: Migraine
Interventions: BIOLOGICAL: ALD403|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CS0159 in Chinese Patients With PBC (Primary Biliary Cholangitis)
Status: RECRUITING
Conditions: Primary Biliary Cholangitis (PBC)
Interventions: DRUG: 2mg CS0159|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Epirubicin and Docetaxel in the Treatment of Patients With Metastatic Breast Cancer
Status: TERMINATED
Conditions: Breast Cancer
Interventions: DRUG: Docetaxel|DRUG: Epirubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Dance on the Turning Characteristics of Patients With Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson Disease(PD)
Interventions: OTHER: Dance|OTHER: No intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of ABT-199 (GDC-199) In Patients With Relapsed Or Refractory Waldenström Macroglobulinemia
Status: COMPLETED
Conditions: Waldenstrom Macroglobulinemia
Interventions: DRUG: ABT199
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Switching to a FDC of B/F/TAF From E/C/F/TAF, E/C/F/TDF, or ATV+RTV+FTC/TDF in Virologically Suppressed HIV-1 Infected Women
Status: COMPLETED
Conditions: HIV-1 Infection
Interventions: DRUG: E/C/F/TAF|DRUG: E/C/F/TDF|DRUG: ATV|DRUG: RTV|DRUG: FTC/TDF|DRUG: B/F/TAF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Motivational Interview for Daily Living Activities in Elderly People Undergoing Total Knee Replacement
Status: COMPLETED
Conditions: Motivation|Behavior, Health|Nursing Caries|Nurse's Role
Interventions: OTHER: Motivational interview|OTHER: Ongoing treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: CAROLINA: Cardiovascular Outcome Study of Linagliptin Versus Glimepiride in Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: linagliptin|DRUG: glimepiride|DRUG: linagliptin placebo|DRUG: glimepiride placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Multi-center Study to Investigate the Safety, Tolerability, Pharmacodynamics and Pharmacokinetics of R7103 Following Repeated Inhalation in Patients With Moderate-to-severe Chronic Obstructive Pulmonary Disease
Status: WITHDRAWN
Conditions: COPD
Interventions: DRUG: R7103
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Investigation of LBX1, TIMP2, GPR126 and CHD7 Gene Polymorphisms in Adolescent Idiopathic Scoliosis Patients
Status: COMPLETED
Conditions: Adolescent Idiopathic Scoliosis|Single Nucleotide Polymorphisms
Interventions: OTHER: single nucleotide polymorphisms
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Active and Passive Perioperative Warming Techniques in Reducing Intraoperative Blood Loss
Status: UNKNOWN
Conditions: Hypothermia|Blood Loss,|Blood Coagulation Disorders
Interventions: DEVICE: Bair Hugger forced air warming system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Latent Pulmonary Hypertension (PH) in Chronic Thromboembolic Pulmonary Hypertension (CTEPH )After Endarterectomy and Influence of Exercise and Respiratory Therapy
Status: UNKNOWN
Conditions: Pulmonary Hypertension|Chronic Thromboembolic Pulmonary Hypertension
Interventions: BEHAVIORAL: exercise and respiratory therapy|OTHER: sedentary control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Shockwave Therapy on Post-laminectomy Fibrosis Low Back Pain Patients.
Status: NOT_YET_RECRUITING
Conditions: Post-laminectomy Syndrome
Interventions: DEVICE: Radial Extracorporeal Shock wave Therapy|DEVICE: Transcutaneous Electrical Nerve Stimulation (TENS)|PROCEDURE: McKenzie Back exercises|DEVICE: electric heating pads
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety of Varicella Vaccine, Live in Healthy Children Aged 12~15 Months in the Philippines
Status: ENROLLING_BY_INVITATION
Conditions: Varicella
Interventions: BIOLOGICAL: Varicella Vaccine|BIOLOGICAL: Varivax
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy of Dutogliptin in Patients With Type 2 Diabetes Mellitus (T2DM) on Background Therapy With Pioglitazone
Status: TERMINATED
Conditions: Diabetes Mellitus, Type II
Interventions: DRUG: Placebo|DRUG: Dutogliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Caloric Restriction and Exercise for Protection From Anthracycline Toxic Effects
Status: COMPLETED
Conditions: Breast Cancer Female
Interventions: DIETARY_SUPPLEMENT: 50% caloric restriction|OTHER: Aerobic exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study on Costs and Effects of Waiting Time in Total Hip and Knee Replacements
Status: UNKNOWN
Conditions: Osteoarthritis, Hip|Osteoarthritis, Knee
Interventions: PROCEDURE: Short waiting time|PROCEDURE: Non-fixed waiting time
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: DIAGNOSTIC
Clinical trial: Metabolic and Infectious Diseases in La Réunion (the REUNION Population-based Study)
Status: UNKNOWN
Conditions: Infectious Disease|Cardiovascular Diseases|General Population|Metabolic Disease
Interventions: DIAGNOSTIC_TEST: Blood, DNA, feces, urine, hair and skin microbiota collection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: To Evaluate Transoral Flexible Endoscope With Narrow Band Imaging in Nasopharyngeal Cancer
Status: UNKNOWN
Conditions: Nasopharyngeal Carcinoma
Interventions: DEVICE: transoral flexible endoscope with magnifying narrow band imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: A Safety, Efficacy, and Tolerability Trial of Pregabalin as Add-On Treatment in Pediatric Subjects <4 Years of Age With Partial Onset Seizures.
Status: COMPLETED
Conditions: Partial Onset Seizures
Interventions: DRUG: Pregabalin Dose Level 1|DRUG: Pregabalin Dose Level 2|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Recovery and Survival of EryDex in Non-patient Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: DSP loaded RBC using EryDex System|DRUG: Sham treated RBC using the EryDex System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy Of Platelet Rich Plasma In The Treatment Of Hemiplegıc Shoulder Pain
Status: COMPLETED
Conditions: Shoulder Pain|Shoulder Impingement|Hemiplegia, Infantile|Shoulder Subluxation|Spasticity, Muscle
Interventions: OTHER: PRP|OTHER: Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Chamomile for Chronic Primary Insomnia
Status: COMPLETED
Conditions: Primary Insomnia|Chronic Insomnia
Interventions: DIETARY_SUPPLEMENT: Chamomile High Grade Extract|DRUG: Placebo Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prevention of Chemotherapy Induced Cardiotoxicity in Children With Bone Tumors and Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Cardiotoxicity|Acute Myeloid Leukemia in Children|Bone Tumor
Interventions: DRUG: Capoten®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Dynamic External Fixation in Treatment Distal Radius Fractures - Elderly Patients
Status: COMPLETED
Conditions: Distal Radius Fracture|Multiple Trauma|Elderly Person Maltreatment
Interventions: PROCEDURE: External fixation in treatment the distal radius fracture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy & Safety Study of Bilateral IVT Injection of GS010 in LHON Subjects Due to the ND4 Mutation for up to 1 Year
Status: UNKNOWN
Conditions: Leber Hereditary Optic Neuropathy
Interventions: GENETIC: GS010|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT