pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: rHSC-DIPGVax Plus Checkpoint Blockade for the Treatment of Newly Diagnosed DIPG and DMG
Status: RECRUITING
Conditions: Diffuse Intrinsic Pontine Glioma|Diffuse Midline Glioma, H3 K27M-Mutant
Interventions: BIOLOGICAL: rHSC-DIPGVax|DRUG: Balstilimab|DRUG: Zalifrelimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess Effectiveness and Safety of Efgartigimod in Chinese Patients With Lupus Nephritis (ZL-1103-013)
Status: RECRUITING
Conditions: Lupus Nephritis
Interventions: BIOLOGICAL: efgartigimod IV|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sertraline vs. Placebo in the Treatment of Anxiety in Children and AdoLescents With NeurodevelopMental Disorders
Status: ACTIVE_NOT_RECRUITING
Conditions: Neurodevelopmental Disorders|Autism|Autism Spectrum Disorder|Fragile X Syndrome|Tuberous Sclerosis|22Q11 Deletion Syndrome|22Q11 Deletion|ADHD|Tic Disorders|Tourette Syndrome|Tourette Syndrome in Children|Tourette Syndrome in Adolescence|ADHD - Combined Type|ADHD Predominantly Inattentive Type|ADHD, Predominantly Hyperactive - Impulsive|Anxiety|Anxiety Disorders
Interventions: DRUG: Sertraline|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Economic Evaluation of Prostatic Urethral Lift
Status: ACTIVE_NOT_RECRUITING
Conditions: Benign Prostatic Hyperplasia
Interventions: PROCEDURE: Comparisons between the Prostatic urethral lift (PUL) and the TURP/Laser cohorts|PROCEDURE: Comparison between the Prostatic urethral lift (PUL) and the SNDS cohorts
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Programmed Cell Death 1 + Selected Cell Therapy With Durvalumab (MEDI4736) and Tremelimumab in Metastatic Melanoma
Status: WITHDRAWN
Conditions: Malignant Melanoma
Interventions: DRUG: tremelimumab/durvalumab, ipilimumab/nivolumab and nivolumab monotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: SMD_FLAG-IDA_98: FLAG-IDA in Induction Treatment of High Risk Myelodysplastic Syndromes or Secondary Acute Myeloblastic Leukemia
Status: COMPLETED
Conditions: Myelodysplastic Syndrome|Acute Myeloblastic Leukemia
Interventions: DRUG: Fludarabine|DRUG: Cytarabine|DRUG: G-CSF|DRUG: Idarubicin|PROCEDURE: Peripheral blood stem cell transplantation|PROCEDURE: Bone marrow transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect and Prognosis of Different Operations on Varicocele - a Single-center Clinical Study
Status: UNKNOWN
Conditions: Varicocele; Male Infertile;Varicocelectomy
Interventions: PROCEDURE: open operation|PROCEDURE: microsurgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hamstrings Autograft Versus Tibialis Allograft for Reconstruction of Anterior Cruciate Ligament
Status: COMPLETED
Conditions: Rupture of the Anterior Cruciate Ligament With Instability of the Knee Joint
Interventions: PROCEDURE: autograft tendon|PROCEDURE: allograft tendon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: D-Serine for Enhancing Cognitive Retraining for the Treatment of Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder
Interventions: DRUG: D-serine|BEHAVIORAL: Cognitive retraining
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effect of Venglustat Tablets on Left Ventricular Mass Index in Male and Female Adult Participants With Fabry Disease
Status: RECRUITING
Conditions: Fabry Disease
Interventions: DRUG: Venglustat (GZ402671)|DRUG: Agalsidase alfa|DRUG: Agalsidase beta (GZ419828)|DRUG: Migalastat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Nightlight Falls Prevention Study
Status: ENROLLING_BY_INVITATION
Conditions: Aging|Alzheimer Disease|Dementia Alzheimers|Dementia of Alzheimer Type|Fall Injury
Interventions: OTHER: Novel Lighting Condition|OTHER: Control Lighting Condition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Morphine COnsumption in Joint Replacement Patients, With and Without GaBapentin Treatment, a RandomIzed ControlLEd Study
Status: COMPLETED
Conditions: Postoperative Pain|Total Hip Replacement
Interventions: DRUG: Gabapentin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: GAstric Bypass to Treat obEse Patients With steAdy hYpertension
Status: COMPLETED
Conditions: Systemic Hypertension|Obesity
Interventions: PROCEDURE: Laparoscopic Roux-en-Y gastric bypass (LRYGB)|OTHER: Clinical treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of EKKO Versus Conservative Treatment for Gross Motor Functions in Cerebral Palsy Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Cerebral Palsy
Interventions: COMBINATION_PRODUCT: EKKO therapy|DIAGNOSTIC_TEST: Conservative Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: methylceIlulose or Psyllium on Fermentation of Inulin Assessed Using a Gas Sensing Capsule
Status: COMPLETED
Conditions: Irritable Bowel Syndrome
Interventions: DIETARY_SUPPLEMENT: psyllium|DIETARY_SUPPLEMENT: methylcellulose|DIETARY_SUPPLEMENT: maltodextrin|DIETARY_SUPPLEMENT: inulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Induction of Ovulation by Clomiphene Citrate Following Laparoscopic Surgery for Endometriosis Stage 1 and Stage 2 With and Without Suppression by Dienogest
Status: UNKNOWN
Conditions: Infertility
Interventions: DRUG: Dienogest 2mg|DRUG: Clomiphene citrate 5 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: N-Acetyl Cysteine in Pathologic Skin Picking
Status: COMPLETED
Conditions: Pathologic Skin Picking|Neurotic Excoriation|Psychogenic Excoriation|Dermatillomania
Interventions: DRUG: N-Acetyl Cysteine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Low Dose Promethazine for Postoperative Nausea and Vomiting
Status: TERMINATED
Conditions: Ambulatory Gynecological Laparoscopic Procedures
Interventions: DRUG: Promethazine|DRUG: Promethazine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Improving HIV Screening With Nurse-Based Rapid Testing/Streamlined Counseling
Status: COMPLETED
Conditions: Health Care Quality, Access, and Evaluation|Delivery of Health Care|Immune System Diseases|HIV Infections
Interventions: OTHER: Rates of HIV testing and receipt of results|OTHER: Sexual risk reduction; HIV knowledge improvement|OTHER: Rates of HIV testing and receipt of results|OTHER: Sexual risk reduction; HIV knowledge improvement|OTHER: Rates of HIV testing and receipt of results|OTHER: Sexual risk reduction; HIV knowledge improvement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Effects of Internet / Web-based Exercises on the Population With Knee Arthritis
Status: COMPLETED
Conditions: Knee Osteoarthritis|Knee Pain Chronic|Sleep Disturbance
Interventions: OTHER: Internet based exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Prevention of Recurrent Gastric or Duodenal Ulcers Caused by Low-dose Aspirin With Rabeprazole (E3810) Treatment (Planetarium Study)
Status: COMPLETED
Conditions: Gastric or Duodenal Ulcers Caused by Low-dose Aspirin
Interventions: DRUG: E3810|DRUG: E3810|DRUG: Teprenone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Hypoxic-hyperoxic Preconditioning in Cardio-surgical Patients
Status: COMPLETED
Conditions: Myocardial Reperfusion Injury|Hypoxia|Hyperoxia|Coronary Artery Disease
Interventions: PROCEDURE: Hypoxic-hyperoxic preconditioning|PROCEDURE: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Study to Assess Safety and Efficacy of Ambrisentan in Subjects With Pulmonary Arterial Hypertension.
Status: COMPLETED
Conditions: Pulmonary Arterial Hypertension
Interventions: DRUG: ambrisentan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Trial of Endoscopic Ultrasound (EUS) - Guided Celiac Plexus Neurolysis
Status: COMPLETED
Conditions: Inoperable, Painful Pancreatic Cancer
Interventions: PROCEDURE: EUS-guided celiac plexus neurolysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tolerance and Efficacy of Rituximab in Sjogren's Disease
Status: COMPLETED
Conditions: Sjogren's Disease
Interventions: DRUG: Rituximab (mabthera) Injection|DRUG: Placebo: NaCl 0.9% or Glucose 5%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Various Insulin Regimens for Diabetic Inpatients With Cirrhosis Trial
Status: UNKNOWN
Conditions: Type 2 Diabetes|Liver Cirrhosis
Interventions: DRUG: Glargine & Glulisine|DRUG: Regular insulin|DRUG: NPH & regular insulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Between UPPP and Tonsillectomy in Adult OSA
Status: TERMINATED
Conditions: Obstructive Sleep Apnea
Interventions: PROCEDURE: tonsillectomy|PROCEDURE: Uvulopalatopharyngoplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Long-term Efficacy and Safety of V0034 CR 01B Cream in Patients With Moderate-to-severe Uremic Xerosis
Status: COMPLETED
Conditions: Uremic Xerosis
Interventions: DRUG: V0034CR01B|DRUG: V0034CR01B vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Early Strength Training Program in Post-transplant Liver Cases
Status: COMPLETED
Conditions: End Stage Liver DIsease|Chronic Liver Failure|Liver Transplant Disorder|Muscle Loss|Muscle Weakness|Sarcopenia|Fatigue|Quality of Life
Interventions: BEHAVIORAL: Strength Exercise Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Investigator-initiated Study of Apremilast to Demonstrate Efficacy Nummular Eczema
Status: COMPLETED
Conditions: Nummular Eczema|Eczema|Dermatitis Eczema|Nummular Dermatitis
Interventions: DRUG: Apremilast|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Uses of Tacrolimus in Behcet Disease
Status: COMPLETED
Conditions: Oral Ulcer|Behcet Syndrome
Interventions: DRUG: Tacrolimus ointment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Retinal Oxygen Reactivity in Patients Infected With Human Immunodeficiency Virus (HIV)
Status: COMPLETED
Conditions: HIV Infections|Retina|Ocular Physiology
Interventions: DRUG: 100% O2
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Telephone Health Coaching and Remote Exercise Monitoring for Peripheral Artery Disease
Status: COMPLETED
Conditions: Peripheral Artery Disease|Atherosclerosis|Peripheral Arterial Disease|Arterial Occlusive Diseases|Vascular Diseases|Peripheral Vascular Diseases|Cardiovascular Diseases
Interventions: BEHAVIORAL: TeGeCoach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pelvic Floor Muscle Training for Incontinence in Older Women.
Status: COMPLETED
Conditions: Stress Urinary Incontinence
Interventions: BEHAVIORAL: Pelvic floor muscle training and bladder training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sorafenib, Epirubicin, Ifosfamide, and Radiation Therapy Followed By Surgery in Treating Patients With High-Risk Stage II or Stage III Soft Tissue Sarcoma
Status: COMPLETED
Conditions: Sarcoma
Interventions: DRUG: epirubicin hydrochloride|DRUG: ifosfamide|DRUG: sorafenib tosylate|OTHER: immunoenzyme technique|OTHER: immunohistochemistry staining method|OTHER: laboratory biomarker analysis|PROCEDURE: adjuvant therapy|PROCEDURE: neoadjuvant therapy|PROCEDURE: therapeutic conventional surgery|RADIATION: hypofractionated radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adipose Tissue and Immune Activation in HIV
Status: COMPLETED
Conditions: Human Immunodeficiency Virus|Obesity
Interventions: RADIATION: dual-energy X-ray absorptiometry (DEXA) scan|OTHER: Carotid and branchial artery ultrasound|DIAGNOSTIC_TEST: 2-hour oral glucose tolerace test|DIAGNOSTIC_TEST: Blood collection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Efficacy and Safety of Ginkgo Biloba Dropping Pills in the Treatment of Coronary Heart Disease With Stable Angina Pectoris and Depression
Status: UNKNOWN
Conditions: Stable Angina Pectoris Associated With Depression
Interventions: DRUG: Ginkgo biloba dropping pills，best western medicine treatment|DRUG: Mimetic drug of ginkgo biloba dropping pills，best western medicine treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Efficacy and Tolerability Study of Paliperidone Extended-Release (ER) in Participants With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Paliperidone ER
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Potential for Drug Interactions Mediated by CYP3A4 Inhibition With Aramchol in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Aramchol|DRUG: Midazolam|DRUG: Atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Pentoxifylline in Diabetic Kidney Disease
Status: RECRUITING
Conditions: Diabetic Kidney Disease
Interventions: DRUG: Pentoxifylline|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Effects of Gastric Acid Suppression by Rabeprazole and BMS-986165 on How Fast and Complete The Drug is Absorbed Into the Body of Healthy Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BMS-986165|DRUG: Rabeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Psychoeducation on Healthy Lifestyle Behaviors in Individuals With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: BEHAVIORAL: Psychoeducation Based on the Transtheoretical Model on Healthy Lifestyle Behaviors
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Antidiabetic Metformin as a Novel Adjunct to Antidepressants in Major Depressive Disorder Patients
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: Placebo oral tablet|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Free Fatty Acids and 3-hydroxybutyrate on Protein, Glucose, Lipid Metabolism and Intracellular Signals.
Status: COMPLETED
Conditions: Systemic Inflammatory Response Syndrome
Interventions: OTHER: Endotoxin, US standard reference E.coli
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: AMG 102 in Combination With Mitoxantrone and Prednisone in Subjects With Previously Treated Castrate Resistant Prostate Cancer
Status: COMPLETED
Conditions: Cancer|Castrate-Resistant Prostate Cancer|Mestastatic Prostate Cancer|Prostate Cancer
Interventions: DRUG: AMG 102|DRUG: AMG 102|DRUG: Mitoxantrone|DRUG: Placebo|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial on HIPEC With Mitomycin C in Colon Cancer Peritoneal Metastases (GECOP-MMC)
Status: RECRUITING
Conditions: Peritoneal Carcinomatosis|Colon Cancer
Interventions: DRUG: complete cytoreductive surgery plus HIPEC with Mytomicin C for 90 minutes|PROCEDURE: complete cytoreductive surgery without HIPEC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improving Compliance With Medical Testing Guidelines
Status: COMPLETED
Conditions: Breast Cancer|Cervical Cancer|Prostate Cancer|Colon Cancer|Lung Cancer
Interventions: OTHER: Color-coded materials|OTHER: Academic detailing|OTHER: Standard support|OTHER: No academic detailing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Noninvasive Neuromodulation to Reserve Diastolic Dysfunction
Status: COMPLETED
Conditions: Heart Failure, Diastolic
Interventions: DEVICE: transcutaneous vagus nerve stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Post Marketing Safety Study of Sitagliptin Phosphate/Metformin Hydrochloride (JANUMET®) (MK-0431A-235)
Status: TERMINATED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Sitagliptin Phosphate/Metformin HCl (JANUMET®)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Inhaled Nitric Oxide in Neonates With Elevated A-a DO2 Gradients Not Requiring Mechanical Ventilation
Status: TERMINATED
Conditions: Lung Disease|Hypoxemia|Respiratory Acidosis
Interventions: DRUG: nitric oxide for inhalation|DRUG: Oxygen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Mitoguazone Dihydrochloride in Patients With AIDS-Related Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Lymphoma, Non-Hodgkin|HIV Infections
Interventions: DRUG: Mitoguazone
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Investigation of Efficacy of Botulinum Toxin A (Dysport) in Chronic Low Back Pain
Status: TERMINATED
Conditions: Lower Back Pain
Interventions: DRUG: Placebo|DRUG: AbobotulinumtoxinA Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ph I/II Nab-Paclitaxel & Carboplatin w/Concurrent Radiation Therapy for Unresectable Stg III NSCLC
Status: TERMINATED
Conditions: Lung Cancer
Interventions: DRUG: carboplatin|DRUG: nab-paclitaxel|RADIATION: Radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase IIa Study of TAS-205 for Duchenne Muscular Dystrophy
Status: COMPLETED
Conditions: Duchenne Muscular Dystrophy
Interventions: DRUG: TAS-205|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: User Evaluation of the MiniMed 640G Insulin Pump
Status: COMPLETED
Conditions: Type 1 Diabetes|Type 2 Diabetes
Interventions: DEVICE: MiniMed® 640G Insulin Pump and Guardian® Link Transmitter
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Daratumumab/Daratumumab and Hyaluronidase-fihj in Combination With Pomalidomide and Dexamethasone for the Treatment of Patients With Newly Diagnosed AL Amyloidosis: a Prospective, Multicenter, Single-arm Study
Status: RECRUITING
Conditions: Amyloid Light-chain Amyloidosis
Interventions: DRUG: Daratumumab/daratumumab and hyaluronidase-fihj|DRUG: Pomalidomide|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Thromboprophylaxis for Patients Undergoing Surgical Resection for Colon Cancer
Status: COMPLETED
Conditions: Deep Vein Thrombosis|Pulmonary Embolism|Cancer
Interventions: DRUG: Tinzaparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Bioequivalence of Two Formulations of Levothyroxine Sodium 200 Micrograms (mcg) Under Tablet Form
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Puran T4®|DRUG: Eutirox®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effectiveness of Clinician Client Centered Counseling on Sexual Behaviors of Antiretroviral Therapy Patients in Nigeria
Status: COMPLETED
Conditions: HIV
Interventions: BEHAVIORAL: Clinician Client Centered (CCC) Counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy Study of PRV111 in Subjects With Oral Squamous Cell Carcinoma
Status: COMPLETED
Conditions: Oral Squamous Cell Carcinoma
Interventions: DRUG: PRV111 (Cisplatin Transmucosal System)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Efficacy and Safety of MT-3921 in Subjects With Acute Traumatic Cervical Spinal Cord Injury
Status: ACTIVE_NOT_RECRUITING
Conditions: Spinal Cord Injury
Interventions: BIOLOGICAL: MT-3921|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Influence of Post-transjugular Intrahepatic Portosystemic Shunt Hepatic Encephalopathy
Status: UNKNOWN
Conditions: Portal Hypertension|Hepatic Encephalopathy
Interventions: PROCEDURE: trans jugular intrahepatic portal systemic shunt
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of GAIA-102 for Refractory/Relapse Neuroblastomas and Other Malignant Pediatric Solid Tumors
Status: RECRUITING
Conditions: Refractory/Relapse Neuroblastoma|Pediatric Solid Tumors
Interventions: BIOLOGICAL: Biological|BIOLOGICAL: Biological|BIOLOGICAL: Biological
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neuraxial Anesthesia and Restless Leg Syndromes in Cesarean
Status: COMPLETED
Conditions: Cesarean Section|Restless Leg Syndrome
Interventions: PROCEDURE: Spinal anesthesia|PROCEDURE: Epidural anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Circulating Tumor DNA in Peripheral T-cell Lymphomas
Status: RECRUITING
Conditions: Peripheral T-cell Lymphoma|NK/T-Cell Lymphoma
Interventions: DIAGNOSTIC_TEST: Tumor- and plasma-informed, next-generation sequencing (NGS)-based patient-specific droplet digital (dd)PCR assay|DIAGNOSTIC_TEST: 18F-fludeoxyglucose positron emission tomography/computed tomography (FDG-PET/CT)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Design and Evaluation of the Effects of a Physical Therapy Program With Digital Support in Patients With Breast Cancer
Status: RECRUITING
Conditions: Breast Cancer
Interventions: OTHER: Active Comparator: Group 1. Conventional treatment|OTHER: Experimental: Group 2. Experimental treatment.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Single Incision Versus Three Planned Incisions to Reduce Pre-operative Astigmatism After Phacoemulsification.
Status: UNKNOWN
Conditions: Astigmatism of Both Eyes
Interventions: PROCEDURE: Planned incisions during phacoemulsification
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Prevention of Post Operative Urinary Retention After Thoracic Surgery Trial
Status: NOT_YET_RECRUITING
Conditions: Urinary Retention Postoperative
Interventions: DRUG: Tamsulosin Hydrochloride|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Reducing the Oxygen Concentration From 5% to 2% on ICSI Outcome
Status: RECRUITING
Conditions: IVF
Interventions: OTHER: Reducing the Oxygen Concentration From 5% to 2%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Efficiency of an Optimized Care Organization for Fibromyalgia Patients. The FIMOUV 2 Study
Status: RECRUITING
Conditions: Fibromyalgia|Physical Activity
Interventions: OTHER: physical activity program|OTHER: Advice and recommendations of physical activity at home
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Trilaciclib, a CDK 4/6 Inhibitor, in Patients Receiving Docetaxel for Metastatic Non-Small Cell Lung Cancer (NSCLC) (PRESERVE 4)
Status: TERMINATED
Conditions: Metastatic Non-Small Cell Lung Cancer|NSCLC|Lung Cancer
Interventions: DRUG: Trilaciclib|DRUG: Placebo|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Influenza H1N1 Vaccine in Adults With Lymphoid Malignancies on Chemotherapy
Status: COMPLETED
Conditions: Lymphoma|Multiple Myeloma|Influenza A Virus, H1N1 Subtype
Interventions: BIOLOGICAL: AS03-adjuvanted H1N1 pandemic influenza vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Mindfulness Research Program: Designed to Enhance Wellbeing in People Living With Dementia and Their Spouses
Status: COMPLETED
Conditions: Dementia
Interventions: BEHAVIORAL: Mindfulness-Based Cognitive Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Examining the Role of Perceived Body Boundaries and Spatial Frame of Reference in the Effect of a Mindfulness Meditation in Emotional Eating
Status: COMPLETED
Conditions: Eating Behavior
Interventions: OTHER: Meditation practice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effectiveness of Two Types of Treatment in Restoring Muscle After Hip or Knee Surgery
Status: COMPLETED
Conditions: Hip Fracture|Osteoarthritis|Femur Head Necrosis
Interventions: DRUG: Essential amino acid supplement|DRUG: Ketoconazole|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Effects of Osteopathic Manipulative Treatment on Postural Control in Parkinson's Disease/Pisa Syndrome Patients
Status: COMPLETED
Conditions: Parkinson Disease and Pisa Syndrome
Interventions: PROCEDURE: Osteopathic Manipulative Treatment (OMT)+ Multidisciplinary Intensive Rehabilitation Treatment (MIRT)|PROCEDURE: Sham Osteopathic Manipulative Treatment (SOMT)+ Multidisciplinary Intensive Rehabilitation Treatment (MIRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Botulinum Toxin Injection With Prostate Brachytherapy
Status: WITHDRAWN
Conditions: Prostate Cancer|Lower Urinary Tract Symptoms|Radioactive Seed Implantation
Interventions: DRUG: Botox injection|DRUG: Saline injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Trial to Investigate the Effect of Schistosoma Mansoni Infection on the Response to Vaccination With MVA85A in BCG-vaccinated African Adolescents
Status: COMPLETED
Conditions: Tuberculosis
Interventions: BIOLOGICAL: MVA85A
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Clinical Trial on Alpha Lipoic Acid in Diabetic Macular Edema
Status: COMPLETED
Conditions: Diabetes Mellitus|Macular Edema
Interventions: DRUG: 1,2 dithiolane 3 valeric acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Randomized Controlled Trial to Evaluate of Dexmedetomidine for the Effect on Operative Visibility in Patients Undergoing Endoscopic Sinus Surgery
Status: COMPLETED
Conditions: Chronic Sinusitis
Interventions: DRUG: Propofol and dexmedetomidine|DRUG: propofol and remifentanil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: STRIDE - STimulating Immune Response In aDvanced brEast Cancer
Status: TERMINATED
Conditions: Breast Cancer
Interventions: BIOLOGICAL: Tecemotide (L-BLP25) and Hormonal Treatment|BIOLOGICAL: Placebo of tecemotide (L-BLP25) and Hormonal Treatment|DRUG: cyclophosphamide|DRUG: sodium chloride (NaCl)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Drug-drugs Interaction Between Lobeglitazone and Empagliflozin
Status: UNKNOWN
Conditions: Diabetes Mellitus, Type II
Interventions: DRUG: Empagliflozin 25mg|DRUG: Lobeglitazone 0.5mg|DRUG: Empagliflozin 25mg/Lobeglitazone 0.5mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Evaluation of Intranasal, Intramuscular, and Oral Naltrexone in Healthy Volunteers
Status: COMPLETED
Conditions: Opioid-Related Disorders
Interventions: DRUG: Naltrexone|OTHER: Intravail
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Self-paced Versus Moderate Intensity Physical Activity Recommendation for Midlife Adults
Status: RECRUITING
Conditions: Physical Inactivity
Interventions: BEHAVIORAL: Self-Paced Intensity Physical Activity|BEHAVIORAL: Prescribed Moderate Intensity Physical Activity
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Mitochondrial Oxidative Stress and Vascular Health in Chronic Kidney Disease
Status: UNKNOWN
Conditions: Chronic Kidney Disease
Interventions: DIETARY_SUPPLEMENT: MitoQ|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dexmedetomidine in Reducing Incidence of Emergence Agitation After Nasal Surgery
Status: COMPLETED
Conditions: Postoperative Delirium
Interventions: DRUG: Dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Spatial Repellents for Vector Control
Status: COMPLETED
Conditions: Malaria
Interventions: DEVICE: Transfluthrin|DEVICE: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Quality of Life After Conservative Oncoplastic Surgery in Breast Cancer Patients (IRONY: lIfe afteR ONcoplastic surgerY)
Status: RECRUITING
Conditions: Breast Cancer
Interventions: OTHER: Study and recording of post-surgical clinical and pathological data of patients diagnosed with breast cancer undergoing unilateral or bilateral conservative oncoplastic surgery.|OTHER: Study and recording of any associated post-surgical complications (of patients diagnosed with breast cancer undergoing unilateral or bilateral conservative oncoplastic surgery.|OTHER: Study and recording of aesthetic and functional post-surgical results related to the quality of life, as data perceived by the surgeon (technical analysis), and by the patient.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: CFI-400945 and Durvalumab in Patients With Advanced Triple Negative Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: CFI-400945|DRUG: Durvalumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy/Safety of Imprime PGG With Cetuximab & Paclitaxel/Carboplatin Therapy in Pts With Untreated Advanced Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: NSCLC
Interventions: BIOLOGICAL: Imprime PGG Injection|BIOLOGICAL: Cetuximab|DRUG: Paclitaxel|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose Ranging Study of the Safety and Efficacy of Orally Administered Lyophilized Fecal Microbiota Product (PRIM-DJ2727) for the Treatment of Recurrent Clostridium Difficile Infection (CDI)
Status: TERMINATED
Conditions: Recurrent C. Difficile Infection
Interventions: BIOLOGICAL: Low fecal microbiota dose|BIOLOGICAL: Mid fecal microbiota dose|BIOLOGICAL: High fecal microbiota dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Capsular Repair on the Outcomes of Direct Anterior Total Hip Arthroplasty.
Status: UNKNOWN
Conditions: Coxarthrosis
Interventions: PROCEDURE: Capsule repair|PROCEDURE: capsulectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Chronic Pain After Spinal Cord Injury (SCI) or Amputation
Status: COMPLETED
Conditions: Spinal Cord Injuries|Amputation, Traumatic|Pain
Interventions: BEHAVIORAL: cognitive therapy|PROCEDURE: Physical Therapy|DRUG: Methadone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: The Utility of Virtual Reality in the Management of Pediatric Functional Constipation With Pelvic Floor Dysfunction.
Status: COMPLETED
Conditions: Functional Constipation|Pelvic Floor Disorders
Interventions: DEVICE: Oculus go headset/virtual reality headset|BEHAVIORAL: Diaphragmatic breathing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Curve of Spee: Speed of Leveling Using Different Orthodontic Archwires
Status: COMPLETED
Conditions: Orthodontic Treatment
Interventions: PROCEDURE: 0.017X0.025 Stainless steel|PROCEDURE: 0.019X0.025 Stainless steel|PROCEDURE: 0.021X0.025 B-Titanium archwire
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lactoferrin in Helicobacter Pylori Eradication Either With Standard Triple Therapy or Sequential Therapy
Status: COMPLETED
Conditions: Helicobacter Pylori Infection
Interventions: DRUG: Esomeprazole 40 milligrams Oral Tablet|DRUG: Amoxicillin 1000 milligrams tablets|DRUG: Clarithromycin 500 milligrams Tablets|DRUG: MetroNIDAZOLE 500 milligrams Oral Tablet|DRUG: Lactoferrin Bovine sachets 200 milligrams
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate a 13-valent Pneumococcal Conjugate Vaccine in Infants
Status: COMPLETED
Conditions: Vaccines, Pneumococcal
Interventions: BIOLOGICAL: 13 valent pneumococcal conjugate vaccine with Polysorbate 80|BIOLOGICAL: 13 valent pneumococcal conjugate vaccine without Polysorbate 80
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: BLI850-302: BLI850 vs an Approved Active Control Bowel Preparation in Adult Subjects Undergoing Colonoscopy
Status: COMPLETED
Conditions: Colon Cancer
Interventions: DRUG: BLI850|DRUG: polyethylene glycol 3350 based bowel preparation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Self-management of Type 1 Diabetes Under Functional Insulin Therapy
Status: TERMINATED
Conditions: Type 1 Diabetes|Basal-bolus Multiple-dily Insulin Injections|Insulin Pump (CSII)
Interventions: OTHER: Training course to functional insulin therapy|OTHER: Usual diabetes management.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study Assessing Long-teRm Outcomes of dupiluMAb (DUPIXENT®) Treatment in Adult Patients With Chronic Rhinosinusitis With Nasal Polyposis (CRSwNP)
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Rhinosinusitis With Nasal Polyposis
Interventions: DRUG: DUPIXENT®
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Lucentis for Macular Edema Associated With Central Retinal Vein Occlusion
Status: COMPLETED
Conditions: Central Retinal Vein Occlusion
Interventions: DRUG: Ranibizumab (Lucentis)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intermittent Suction Technique in the Diagnosis of Pancreatic Solid Lesions
Status: COMPLETED
Conditions: Pancreatic Cancer|Pancreatic Neoplasms
Interventions: PROCEDURE: Intermittent aspiration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Interaction Between Omeprazole and Gliclazide in CYP2C19 Normal/ Ultrarapid Metabolisers
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Omeprazole|DRUG: Placebo oral tablet|DRUG: Gliclazide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Vaccine Therapy and Radiation to Liver Metastasis in Patients With CEA-Positive Solid Tumors
Status: COMPLETED
Conditions: Liver Neoplasms
Interventions: DRUG: rV-CEA(6D)/TRICOM-rF-CEA(6D)/TRICOM|DRUG: rF-CEA(6D)/TRICOM|DRUG: Recombinant Fowlpox-GM-CSF|DRUG: Celecoxib
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: The Effect of Protein-enriched Diet on Body Composition and Appetite
Status: COMPLETED
Conditions: Overweight|Obese|Metabolic Syndrome|Non Alcoholic Fatty Liver Disease
Interventions: DIETARY_SUPPLEMENT: High Protein, low calorie meal replacement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Local Opera Viewing Combined Medical Gymnastics for Elderly PSCI
Status: NOT_YET_RECRUITING
Conditions: Post-stroke Cognitive Impairment
Interventions: BEHAVIORAL: Local opera appreciating and Medical gymnastics training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Evaluate the Safety, Pharmacokinetics and Pharmacodynamics of N-Rephasin® SAL200 in Healthy Male Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers|Anti-Bacterial Agents|Methicillin-Resistant Staphylococcus Aureus
Interventions: BIOLOGICAL: N-Rephasin® SAL200|OTHER: INT200-Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Tenecteplase Versus Alteplase for Thrombolysis (Clot Dissolving) in Acute Ischemic Stroke
Status: COMPLETED
Conditions: Ischemic Stroke
Interventions: DRUG: Tenecteplase|DRUG: Alteplase
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Consumption of Orange-fleshed Sweet Potatoes on the Vitamin A Status of Bangladeshi Women of Reproductive Age
Status: COMPLETED
Conditions: Vitamin A Deficiency
Interventions: OTHER: White-fleshed sweet potatoes|OTHER: Orange-fleshed sweet potatoes (boiled)|OTHER: Orange-fleshed sweet potatoes (fried)|OTHER: WFSP and capsule of retinyl palmitate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Compare the Compliance of Patients Treated With Once-daily (od) or Twice-daily (Bid) Glimepiride and Metformin Fixed Combination Therapy
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Glimepiride/ Metformin|DRUG: Glimepiride/ Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Assessing the Safety and Efficacy of Dextenza® for the Treatment of Ocular Pain and Inflammation Following Surgery for Pediatric Cataract
Status: COMPLETED
Conditions: Cataract
Interventions: DRUG: Dextenza Ophthalmic Insert|DRUG: Prednisolone acetate ophthalmic suspension USP 1%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endometriosis Transcriptomic Cell Atlas
Status: NOT_YET_RECRUITING
Conditions: Endometriosis|Infertility
Interventions: PROCEDURE: Endometriosis|PROCEDURE: Tubal ligation or Hysterectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Safe, Healthy, Adolescent Relationships and Peers
Status: COMPLETED
Conditions: Juvenile Delinquency Unspecified|Risk Behavior|Adolescent Behavior|Sexual Behavior|Drug Use
Interventions: BEHAVIORAL: Parent Ed. and Youth Skills Coaching|BEHAVIORAL: Services as Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Low-dose Spinal Morphine for Post-Thoracotomy Pain After Video-Assisted Thoracoscopic Surgery
Status: COMPLETED
Conditions: Video-assisted Thoracoscopic Surgery
Interventions: DRUG: Morphine|OTHER: control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT