pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Efficacy Evaluation of Dotarem Compared to Gadovist in the Diagnosis of Peripheral Arterial Disease
Status: COMPLETED
Conditions: Peripheral Arterial Disease
Interventions: DRUG: Dotarem|DRUG: Gadovist
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation of Osseo-integration After Placement of Dental Implants With Patients Receiving Radiotherapy for Buccopharyngeal Oncology
Status: WITHDRAWN
Conditions: Dental Implants
Interventions: PROCEDURE: Evaluation of the success rate of implants
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Low-residue Full Nutritive Formula Powder in Bowel Preparation for Colonoscopy
Status: RECRUITING
Conditions: Bowel Preparation for Colonoscopy
Interventions: DIETARY_SUPPLEMENT: Low-residue full nutrition formula podwer|DIETARY_SUPPLEMENT: Self-prepared low-residue diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Secukinumab Study in PSOriasis Exploring pruRITUS Intensity and Lesional Biomarkers
Status: COMPLETED
Conditions: Psoriasis
Interventions: BIOLOGICAL: Secukinumab|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Controlling Femoral Extension and Derotation Osteotomy In Cerebral Palsy With Electromagnetic Tracking
Status: UNKNOWN
Conditions: Interal Rotation Gait|Crouch Gait|Cerebral Palsy|Malalignment
Interventions: PROCEDURE: Femoral Extension and Derotation Osteotomy (ExtFDO)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Rituximab in Patients With Relapsed or Refractory TTP-HUS
Status: UNKNOWN
Conditions: Thrombotic Thrombocytopenic Purpura|Hemolytic Uremic Syndrome
Interventions: DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SGI-110 in Adults With Untreated Acute Myeloid Leukemia (AML), Not Considered Candidates for Intensive Remission Induction
Status: COMPLETED
Conditions: Leukemia, Myeloid, Acute
Interventions: DRUG: SGI-110 (guadecitabine)|DRUG: Treatment Choice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare the Efficacy and Safety of Ifosfamide and Etoposide With or Without Lenvatinib in Children, Adolescents and Young Adults With Relapsed and Refractory Osteosarcoma
Status: COMPLETED
Conditions: Osteosarcoma
Interventions: DRUG: Lenvatinib|DRUG: Ifosfamide|DRUG: Etoposide|DRUG: Lenvatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of High Dose Arginine Infusion on Hemodynamic and Peripheral Microcirculation
Status: COMPLETED
Conditions: Peripheral Arterial Occlusive Disease
Interventions: DIETARY_SUPPLEMENT: Arginine|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Metabolic Syndrome in PCOS: Precursors and Interventions
Status: COMPLETED
Conditions: Polycystic Ovary Syndrome|Metabolic Syndrome
Interventions: DRUG: flutamide|DRUG: ethinyl estradiol 35 mcg and drospirenone 3 mg|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: A Psychoeducational Program "BalancingMySwing" for Patients With Bipolar Disorder
Status: COMPLETED
Conditions: Bipolar Disorder
Interventions: BEHAVIORAL: Psychoeducational Program "BalancingMySwing"
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mindfulness-based Dance/Movement Therapy for Chronic Low Back Pain
Status: UNKNOWN
Conditions: Chronic Low-back Pain
Interventions: BEHAVIORAL: Mindfulness-based dance/movement therapy (M-DMT)|BEHAVIORAL: Chronic pain social support group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant PD-1 Blockade in Patients With Stage IIB/C Melanoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Melanoma
Interventions: DRUG: Pembrolizumab|PROCEDURE: Wide Excision and Sentinel Lymph Node (SLN) Biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Minocycline and Proteinuria in Diabetic Nephropathy
Status: UNKNOWN
Conditions: Diabetic Nephropathy
Interventions: DRUG: Minocycline 100 mg po bid for 6 months|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CHoice of Optimal Anti-Thrombotic Strategy in Patients Undergoing Implantation of Coronary Drug-Eluting Stents 4
Status: RECRUITING
Conditions: Coronary Artery Disease
Interventions: DEVICE: Type of stent|DRUG: Duration of DAPT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intermediate Vision in a Driving Simulator Environment: Comparison of the J&J EYHANCE With a Conventional Monofoc. IOL
Status: COMPLETED
Conditions: Lenses, Intraocular|Pseudophakia|Near Vision|Driving
Interventions: OTHER: Posterior chamber intraocular lens (IOL)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of Systemic Chemotherapy With/Without HAI in Patients With Initially Unresectable Colorectal Liver Metastasis
Status: RECRUITING
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: mFOLFOX6|DRUG: HAI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Muscle Dysfunction in Patients With Chronic Obstructive Lung Disease (COPD): the Role of Sympathetic Activation
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DEVICE: non-invasive ventilation (NIV)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nutritional Therapy Improves Dyslipidemia in HIV Infected Teenagers With Antiretroviral Treatment
Status: COMPLETED
Conditions: Adolescent Behavior|Hiv|Dyslipidemias
Interventions: BEHAVIORAL: Nutritional therapy|BEHAVIORAL: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Impact of a Predictive Score of Bowel Preparation Quality in Clinical Practice
Status: COMPLETED
Conditions: Cleansing Quality of the Colon
Interventions: DRUG: polyethylene glycol|DRUG: polyethylene glycol plus ascorbic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Effectiveness of Sacral Foam Pad in Preventing Pressure Injury in Surgical Patients With Supine Position
Status: UNKNOWN
Conditions: Pressure Ulcer
Interventions: DEVICE: Mepilex Border Sacrum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Thromboembolic Risk Stratification by TRiP(Cast) Score to Guide Physicians in Preventive Treatment Prescriptions for Patients With Lower Limb Trauma Requiring Brace or castING.
Status: COMPLETED
Conditions: Lower Limb Trauma|Venous Thromboembolism|Stratification
Interventions: OTHER: TRIPscore
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Challenging the Gold Standard: Pilot Study Comparing Continuous Glucose Monitoring System (CGMS), Capillary Glucose Monitors and 3 Hour Glucose Tolerance Test (GTT) to Diagnose Gestational Diabetes Mellitus (GDM)
Status: COMPLETED
Conditions: Diabetes, Gestational
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Evaluate Safety and Tolerability of Subcutaneous Doses of MEDI-545 in Subjects With Lupus
Status: COMPLETED
Conditions: Lupus Erythematosus, Systemic|Lupus
Interventions: DRUG: MEDI-545|DRUG: MEDI-545|DRUG: MEDI-545|DRUG: MEDI-545|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Docetaxel + Plinabulin Compared to Docetaxel + Placebo in Patients With Advanced NSCLC
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: Docetaxel + Plinabulin (DP)|DRUG: Docetaxel (D)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Targeted Potassium Levels for Prevention of ICD Therapy
Status: UNKNOWN
Conditions: Ventricular Arrhythmias and Cardiac Arrest|Implantable Defibrillator User|Hypokalemia|Hyperkalemia|Ventricular Tachycardia|Atrial Fibrillation
Interventions: COMBINATION_PRODUCT: Targeted serum potassium level
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Exploiting Circulating Tumour DNA to Intensify the Postoperative Treatment Resected Colon Cancer Patients
Status: RECRUITING
Conditions: Stage II Colon Cancer|Stage III Colon Cancer|HER2-positive Colon Cancer|RAS Wild-type Colon Cancer
Interventions: DRUG: 5-Fluorouracil continuous infusion FOLFOXIRI schedule|DRUG: 5-Fluorouracil bolus FOLFOX schedule|DRUG: 5-Fluorouracil continuous infusion FOLFOX schedule|DRUG: Oxaliplatin FOLFOX and FOLFOXIRI schedule|DRUG: Oxaliplatin CAPOX schedule|DRUG: L-Leucovorin|DRUG: Capecitabine|DRUG: Irinotecan|DRUG: Trifluridine/Tipiracil|DRUG: Trastuzumab|DRUG: Tucatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stereotactic Body Radiation Therapy for Inoperable Locally-advanced Non-small Cell Lung Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-small Cell Lung Cancer
Interventions: RADIATION: Stereotactic Body Radiation Therapy (SBRT)|DRUG: cisplatin or carboplatin-based
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vaginal Isonicotinic Acid Hydrazide (INH) Administration Prior to T380A Intrauterine Device Insertion
Status: COMPLETED
Conditions: IUCD Complication
Interventions: DRUG: INH|DRUG: Placebo Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Radotinib Versus Imatinib in Newly Diagnosed Philadelphia Chromosome and Chronic Myeloid Leukemia Chronic Phase Patients
Status: COMPLETED
Conditions: Leukemia|Leukemia, Myeloid|Leukemia, Myelogenous, Chronic, BCR-ABL Positive|Philadelphia Chromosome|Bone Marrow Diseases|Hematologic Diseases
Interventions: DRUG: Imatinib|DRUG: Radotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Safety and Efficacy of CD-801 in Patients With Advanced Intrahepatic Cholangiocarcinoma
Status: NOT_YET_RECRUITING
Conditions: Intrahepatic Cholangiocarcinoma
Interventions: GENETIC: Injection of CD-801, a lipid nanoparticle-encapsulated self-replicating RNA encoding hepatocyte nuclear factor 4α (HNF4α)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I Study of Biweekly SIRB Regimen for Metastatic Colorectal Cancer
Status: WITHDRAWN
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: S-1|DRUG: Irinotecan|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diagnosis of Laryngeal Lesions Using the Probe-based Confocal Laser Endomicroscopy
Status: UNKNOWN
Conditions: Laryngeal Leiomyoma|Probe-based Confocal Laser Endomicroscopy
Interventions: DIAGNOSTIC_TEST: Confocal Laser Endomicroscopy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Use of Lung Ultrasonography in the Delivery Room in Neonates
Status: ENROLLING_BY_INVITATION
Conditions: Suspected Damage to Fetus From Other Disease in the Mother, Affecting Management of Mother, With Delivery|Patient Death or Serious Disability Associated With A Haemolytic Reaction Due to the Administration of ABO-Incompatible Blood or Blood Products
Interventions: DIAGNOSTIC_TEST: doing lung ultrasonography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparison of Minimal Versus Conventional Extracorporeal Circulation in Coronary Surgery
Status: COMPLETED
Conditions: Coronary Artery Bypass
Interventions: PROCEDURE: Coronary artery bypass grafting with the use of minimal invasive extracorporeal circulation|PROCEDURE: Coronary artery bypass grafting under conventional extracorporeal circulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Low Dose Magnesium Sulphate Versus Standard Pritchard Regimen In Management Of Severe Preeclampsia/Eclampsia
Status: COMPLETED
Conditions: Preeclampsia/Eclampsia
Interventions: DRUG: Low dose magnesium sulphate|DRUG: Pritchard regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Impact of Diazepam 1% Oral Gel Efficacy in Burning Mouth Syndrome
Status: COMPLETED
Conditions: Burning Mouth Syndrome
Interventions: DRUG: Diazepam 1% oral gel|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: VLCD & Adjuvant Exercise Effect in Overweight Diabetic Men
Status: COMPLETED
Conditions: Diabetes Mellitus Type 2 in Obese
Interventions: DIETARY_SUPPLEMENT: Very Low Calorie Diet|OTHER: High Intensity Interval Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cognitive Behavioral Therapy in Treating Anxiety in Patients With Stage IV Non-Small Cell Lung Cancer and Their Caregivers
Status: COMPLETED
Conditions: Anxiety Disorder|Recurrent Non-small Cell Lung Cancer|Stage IV Non-small Cell Lung Cancer
Interventions: OTHER: counseling intervention|OTHER: questionnaire administration|PROCEDURE: quality-of-life assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Ranolazine on Coronary Microvascular Dysfunction in Patients With Hypertrophic Cardiomyopathy
Status: COMPLETED
Conditions: HCM - Hypertrophic Non-Obstructive Cardiomyopathy
Interventions: DRUG: Ranolazine PR (prolonged-release) 500 mg 1 tablet bis in die and 750 mg 1 tablet bis in die
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CKD-828(80/2.5mg) Pharmacokinetic Study_2nd
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: CKD-828(FDC)|DRUG: Combination Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Kinesio Taping Versus Myofascial Release on Menstrual Low Back Pain
Status: NOT_YET_RECRUITING
Conditions: Low Back Pain
Interventions: OTHER: kinesio taping|OTHER: myofascial release technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hypofractionated Image-Guided Radiotherapy (IGRT) With Organ Motion Mitigation and Urethral Sparing for Prostate Cancer
Status: UNKNOWN
Conditions: Adenocarcinoma of the Prostate
Interventions: RADIATION: IGRT 45 Gy in 5 fractions of 9 Gy|PROCEDURE: Image-guided, volumetric intensity-modulated arc radiotherapy (IGRT-VMAT)|DEVICE: Rectal balloon with air filling|DEVICE: Urethral catheter loaded with beacon transponders
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Noninvasive Pre-surgical Evaluation of Patients With Focal Epilepsy and Establishment of a Normative Imaging Database
Status: RECRUITING
Conditions: Epilepsy
Interventions: DEVICE: MRI|DEVICE: MEG
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: MBSR in a Hispanic Immigrant Population in St. Louis
Status: COMPLETED
Conditions: Mindfulness|Emotional Well-being
Interventions: BEHAVIORAL: Mindfulness Based Stress Reduction Adapated (MBSR-A)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Single Escalating Dose Study Of HSK7653 In Healthy Subjects
Status: COMPLETED
Conditions: T2DM (Type 2 Diabetes Mellitus)
Interventions: DRUG: HSK7653|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 2a Study to Evaluate the Safety and Efficacy of Cannabidiol Only as Maintenance Therapy and Steroid Sparing in Patients With Stable Autoimmune Hepatitis
Status: TERMINATED
Conditions: Autoimmune Hepatitis
Interventions: DRUG: Cannabidiol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Transversus Abdominis Plane Block on Diaphragm Thickness
Status: COMPLETED
Conditions: Diaphragm; Relaxation
Interventions: PROCEDURE: Transabdominal plane block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: High-flow Conditioned Oxygen Therapy Versus Non-invasive Ventilation: Prevention of Post-extubation Failure
Status: COMPLETED
Conditions: Post-extubation Respiratory Failure
Interventions: DEVICE: High Flow Conditioned Oxygen Therapy in High Risk Patients|DEVICE: Non-invasive mechanical ventilation|DEVICE: Conventional Oxygen Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acute vs. Delayed Iron Therapy: Effect on Iron Status, Anemia and Cognition
Status: COMPLETED
Conditions: Anemia|Inflammation|Malaria Morbidity|Cognitive Development
Interventions: DIETARY_SUPPLEMENT: Ferrous Sulphate Syrup
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: FIGO 2018 Stage IB2 Cervical Cancer Treated With Neoadjuvant Chemotherapy Followed by Fertility Sparing Surgery
Status: RECRUITING
Conditions: Cervical Cancer
Interventions: DRUG: Cisplatin|DRUG: Carboplatin|DRUG: Paclitaxel|PROCEDURE: Trachelectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diffusion-weighted MRI for Individualized Radiation Therapy Planning of Lung Cancer
Status: WITHDRAWN
Conditions: Recurrent Non-small Cell Lung Cancer|Stage IIA Non-small Cell Lung Cancer|Stage IIB Non-small Cell Lung Cancer|Stage IIIA Non-small Cell Lung Cancer|Stage IIIB Non-small Cell Lung Cancer
Interventions: DEVICE: diffusion-weighted magnetic resonance imaging|DEVICE: 4-dimensional computed tomography|RADIATION: fludeoxyglucose F 18|DEVICE: FDG-PET
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Non-Interventional Study to Capture the Patient Experience on Gene Therapy for Hemophilia Within the AskBio009-101 Study Through Patient and Investigator Interviews
Status: COMPLETED
Conditions: Hemophilia B
Interventions: OTHER: Qualitative Interview - Participants/ Patients|OTHER: Qualitative Interview - Investigators and Study Coordinators
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Oral Lactobacillus Supplementation as Treatment for Overactive Bladder Syndrome: A Randomised Controlled Trial
Status: NOT_YET_RECRUITING
Conditions: Overactive Bladder Syndrome
Interventions: DIETARY_SUPPLEMENT: OMNi BiOTiC® 41167|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Restoration of the Microbiome Through Superdonor Selection
Status: UNKNOWN
Conditions: Ulcerative Colitis
Interventions: OTHER: superdonor FMT|OTHER: autologous FMT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Randomized Controlled Cocoa-Appetite Trial
Status: COMPLETED
Conditions: Obesity
Interventions: DIETARY_SUPPLEMENT: Lo-Flav|DIETARY_SUPPLEMENT: Hi-Flav|DIETARY_SUPPLEMENT: Epicatechin|DIETARY_SUPPLEMENT: Procyanidins
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Rimonabant/Metformin Combinations to Investigate Diabetes (Blood Sugar) Control in Patients With Type 2 Diabetes
Status: WITHDRAWN
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Rimonabant|DRUG: Metformin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Modified Magill Forceps Facilitating Nasal Intubation for Children Undergoing Dental Operations
Status: UNKNOWN
Conditions: Endotracheal Tube Wrongly Placed During Anesthetic Procedure
Interventions: DEVICE: modified Magill forceps|DEVICE: Magill forceps
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Targeting the Neurobiology of RRB in Autism Using N-acetylcysteine: Trial
Status: RECRUITING
Conditions: Autism Spectrum Disorder
Interventions: DRUG: N acetyl cysteine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Psychological Effects of Different Sedation Protocol on Mechanically Ventilated Critically Ill Adults.
Status: UNKNOWN
Conditions: Sedative Withdrawal Delirium
Interventions: DRUG: Deep sedation(midazolam and fentanyl )|DRUG: Deep and daily interruption of sedation(midazolam and fentanyl )|DRUG: Light sedation(midazolam and fentanyl )
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Resynchronisation Therapy of Right Ventricle in Pulmonary Arterial Hypertension
Status: UNKNOWN
Conditions: Pulmonary Arterial Hypertension
Interventions: PROCEDURE: Resynchronization therapy of right ventricle
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Patiromer Efficacy to Reduce Episodic Hyperkalemia in End Stage Renal Disease Patients
Status: COMPLETED
Conditions: Hyperkalemia|End Stage Renal Disease
Interventions: DRUG: Patiromer Oral Powder Product
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Hyperbaric Oxygen Therapy on Aerobic and Anaerobic Physical Fitness
Status: COMPLETED
Conditions: Healthy|Athletes
Interventions: DEVICE: Hyperbaric Oxygen Therapy|DEVICE: SHAM treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of NOSE and Conventional Methods in Laparoscopic Right Colon Surgery
Status: COMPLETED
Conditions: Surgical Incision
Interventions: PROCEDURE: natural orifice
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Novel Gallium 68 Citrate in Orthopedic Infections
Status: TERMINATED
Conditions: Joint Prosthesis
Interventions: DRUG: 68-Gallium citrate PET/CT scan|DRUG: 18F FDG PET/CT scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Niacin to Improve Blood Flow in People With Sickle Cell Disease
Status: COMPLETED
Conditions: Sickle Cell Disease
Interventions: DRUG: Niacin-ER|DRUG: Placebo|DRUG: L-NMMA|DRUG: Acetylcholine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Decision Making in Video Games
Status: WITHDRAWN
Conditions: Cognitive Change
Interventions: DEVICE: Anodal left dorsolateral prefrontal cortex tDCS stimulation|DEVICE: Anodal right dorsolateral prefrontal cortex tDCS stimulation|DEVICE: Sham tDCS stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Safety Study of Allogeneic HB-adMSCs for the Treatment of COVID-19
Status: TERMINATED
Conditions: COVID-19
Interventions: BIOLOGICAL: HB-adMSC|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Combination Dostarlimab With Niraparib In Patients With Penile Carcinoma
Status: RECRUITING
Conditions: Penile Carcinoma
Interventions: DRUG: Dostarlimab|DRUG: Niraparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence of Ethylenediamine Dihydrochloride Study
Status: COMPLETED
Conditions: Allergic Contact Dermatitis
Interventions: DRUG: Ethylenediamine dihydrochloride allergen patch
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: VSL#3® vs Placebo in the Treatment of Fatigue and Other Symptoms in Long Covid (DELong#3)
Status: RECRUITING
Conditions: Long COVID
Interventions: DIETARY_SUPPLEMENT: VSL#3®|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing the Pharmacokinetic Similarity of MB02-SP, MB02-DM and USlicensed Avastin®.
Status: UNKNOWN
Conditions: Healthy Volunteers
Interventions: DRUG: MB02-SP|DRUG: MB02-DM|DRUG: US licenced Avastin®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Feasibility of a Combination of Graded Pain Exposure and Graded Motor Imagery in People With Complex Regional Pain Syndrome Type 1
Status: RECRUITING
Conditions: Complex Regional Pain Syndrome I (CRPS I)
Interventions: BEHAVIORAL: Experimental group|BEHAVIORAL: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Feasibility Study to Develop a Protocol for Functional Lacrimal Magnetic Resonance Imaging
Status: COMPLETED
Conditions: Lacrimal Duct Obstruction|Lacrimal Stenosis
Interventions: DIAGNOSTIC_TEST: MRI scanning
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Cariostatic and Remineralizing Effects of Three Different Dental Varnishes
Status: COMPLETED
Conditions: Dental Caries in Children|Cariostatic Agent|Resistance, Dental Caries|Fluoride Varnishes
Interventions: DRUG: Nano Silver Fluoride varnish|DRUG: nano-hydroxyapatite varnish|DRUG: sodium Fluoride Varnish
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Cystoprostatectomy Versus Radiotherapy Combined With ADT for the Treatment of cT4 Prostate Cancer With Bladder Invasion
Status: RECRUITING
Conditions: Prostate Cancer
Interventions: PROCEDURE: Cystoprostatectomy|RADIATION: external beam radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 7-day Simvastatin and Emotional Processing
Status: COMPLETED
Conditions: Depression|Inflammation
Interventions: DRUG: Simvastatin 20mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Single Ascending Oral Doses of SY-008 in Healthy Subjects
Status: COMPLETED
Conditions: Diabetes
Interventions: DRUG: SY-008
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Protein Blend Supplementation During Exercise Training on Muscle Growth and Strength
Status: COMPLETED
Conditions: Muscle
Interventions: DIETARY_SUPPLEMENT: Blend|DIETARY_SUPPLEMENT: Whey|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Thiotepa-Clofarabine-Busulfan With Allogeneic Stem Cell Transplant for High Risk Malignancies
Status: COMPLETED
Conditions: Stem Cell Transplantation|Leukemia|Lymphoma
Interventions: DRUG: Thiotepa|DRUG: Clofarabine|DRUG: Busulfan|PROCEDURE: Allogeneic Stem Cell Transplantation|DRUG: Thymoglobulin (ATG)|DRUG: G-CSF (Filgrastim)|DRUG: Tacrolimus|DRUG: Methotrexate|DRUG: Cyclophosphamide|DRUG: Mesna
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Seborrheic Dermatitis: Ketoconazole 2% Foam Versus Ketoconazole 2% Shampoo
Status: COMPLETED
Conditions: Seborrheic Dermatitis
Interventions: DRUG: ketoconazole 2% foam|DRUG: ketoconazole 2% shampoo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Registry to Capture Patient Outcomes With KRAS G12R Altered Advanced Pancreatic Ductal Adenocarcinoma Treated With MEK Inhibitor-based Combination Therapy
Status: RECRUITING
Conditions: Pancreatic Ductal Adenocarcinoma
Interventions: OTHER: combination therapy with no MEKi|DRUG: combination therapy with MEKi-HCQ|DRUG: combination therapy with MEKi-EGFRi|DRUG: combination therapy with MEKi.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Mesalazine 4g Once Daily Versus 4g in Two Divided Doses in Active Ulcerative Colitis.
Status: COMPLETED
Conditions: Ulcerative Colitis
Interventions: DRUG: Mesalazine slow-release granules|DRUG: Mesalazine liquid enema
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: OnabotulinumtoxinA in the Management of Psychogenic Dystonia
Status: COMPLETED
Conditions: Torticollis, Dystonia
Interventions: BEHAVIORAL: CBT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lazertinib and Chemotherapy Combination in EGFR-mutant NSCLC Patients Without ctDNA Clearance After lead-in Lazertinib Monotherapy
Status: NOT_YET_RECRUITING
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: Lazertinib+Pemetrexed+Carboplatin|DRUG: Lazertinib|DRUG: Lazertinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Risk Factors Leading to Conversion From Laparoscopic Cholecystectomy to Open Surgery
Status: COMPLETED
Conditions: Cholelithiasis|Cholecystitis, Acute|Cholecystitis, Chronic|Gallbladder Diseases
Interventions: PROCEDURE: Laparoscopic cholecystectomy|PROCEDURE: Open-conversion cholecystectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rejuvenation of Premature Ovarian Failure With Stem Cells
Status: COMPLETED
Conditions: Primary Ovarian Insufficiency|Low Ovarian Reserve|Premature Ovarian Failure
Interventions: PROCEDURE: ROSE-1 Protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Efficacy of Nobel Parallel CC Implants With on1 Abutment in Posterior Area Participants
Status: RECRUITING
Conditions: Mechanical Failure of Dental Implant Nos
Interventions: COMBINATION_PRODUCT: use on1 abutment instead of healing cap in test group|COMBINATION_PRODUCT: use healing cap in control group
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: SmarToyGym: Smart Detection of Atypical Toy-oriented Actions in At-risk Infants
Status: COMPLETED
Conditions: Cerebral Palsy|Developmental Delay|Stroke|Fine Motor Delay|Infant Development|Other Development Delays
Interventions: DEVICE: SmarToyGym
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Phase 1 Study of ACE-083 in Healthy Subjects
Status: COMPLETED
Conditions: Musculoskeletal Diseases
Interventions: DRUG: ACE-083
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Breast-Conserving Surgery Followed by Radiation Therapy With MRI-Detected Stage I or Stage II Breast Cancer
Status: WITHDRAWN
Conditions: Ductal Breast Carcinoma in Situ|Estrogen Receptor-negative Breast Cancer|Estrogen Receptor-positive Breast Cancer|HER2-negative Breast Cancer|HER2-positive Breast Cancer|Invasive Ductal Breast Carcinoma|Invasive Lobular Breast Carcinoma|Male Breast Cancer|Medullary Ductal Breast Carcinoma With Lymphocytic Infiltrate|Mucinous Ductal Breast Carcinoma|Papillary Ductal Breast Carcinoma|Progesterone Receptor-negative Breast Cancer|Progesterone Receptor-positive Breast Cancer|Stage I Breast Cancer|Stage II Breast Cancer|Tubular Ductal Breast Carcinoma
Interventions: RADIATION: external beam radiation therapy|OTHER: questionnaire administration|PROCEDURE: therapeutic conventional surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 6-Year Follow-up of a Prevention Program for Bereaved Families
Status: COMPLETED
Conditions: Mental Disorders Diagnosed in Childhood
Interventions: BEHAVIORAL: Self- study comparison group|BEHAVIORAL: Family Bereavement Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Cell-Wave Study: Combined Extracorporal Shock Wave Therapy and Intracoronary Cell Therapy in Chronic Ischemic Myocardium
Status: COMPLETED
Conditions: Congestive Heart Failure
Interventions: PROCEDURE: intracoronary stem cell therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Megadyne Ace Incision/Dissection Study
Status: UNKNOWN
Conditions: Abdominoplasty|Bilateral Breast Reduction|Bilateral Breast Lift|Bilateral Brachioplasty|Bilateral Lateral Thigh and Buttocks Lift
Interventions: DEVICE: E-Z Clean ACE Blade
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: REmoval of Free Light Chains. A COmpaRison of Three Different dialyzERs
Status: COMPLETED
Conditions: Complication of Hemodialysis
Interventions: DEVICE: PMMA filter|DEVICE: HFR17 filter|DEVICE: F7 filter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Study Comparing Discontinuation Symptoms Of DVS SR In Subjects With Major Depressive Disorder (MDD)
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: Desvenlafaxine Succinate Sustained-Release Formulation 50 mg|DRUG: Desvenlafaxine Succinate Sustained-Release Formulation 25 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SECOTEX® (Tamsulosin Hydrochloride) Bioequivalence Study Brazil - Fast Admin
Status: COMPLETED
Conditions: Prostatic Hyperplasia
Interventions: DRUG: Test formulation|DRUG: Reference formulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effect of Two Physical Training Programs on Oxygen Uptake and Heart Rate On-kinetics in Patients COPD
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease|Healthy
Interventions: OTHER: Resisted/Aerobic physical training|OTHER: Interval physical training in elliptical equipament|OTHER: Interval physical training in elliptical equipament|OTHER: Resisted/Aerobic physical training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial Comparing Efficacy and Safety of Insulin Degludec and Insulin Glargine in Insulin naïve Subjects With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: Insulin Degludec|DRUG: Insulin Glargine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Humeral Shaft Pseudoarthrosis Treated With Bone Autograft Versus Platelet Rich Plasma
Status: COMPLETED
Conditions: Pseudoarthrosis
Interventions: PROCEDURE: bone autograft of iliac crest|PROCEDURE: Platelet Rich Plasma plus bone autograft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Resistive Exercise on Forearm Blood Flow and Tissue Oxygenation Among Breast Cancer Survivors With or at Risk for Breast Cancer-related Lymphoedema (BCRL)
Status: COMPLETED
Conditions: Lymphedema|Breast Cancer
Interventions: OTHER: Exercise training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety, Reactogenicity, and Immunogenicity of mRNA-1653 in Healthy Adults
Status: COMPLETED
Conditions: Human Metapneumovirus and Human Parainfluenza Infection
Interventions: BIOLOGICAL: mRNA-1653|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Caudal vs. Pudendal Block in Peds GU
Status: WITHDRAWN
Conditions: Hypospadias|Penile Torsion|Chordee|Phimosis
Interventions: PROCEDURE: Caudal Block|PROCEDURE: Ultrasound-guided Pudendal Block|DRUG: Injectable 1 ml/kg of 0.25% ropivacaine with 1mcg/kg dexmedetomidine|DRUG: Injection of 0.5 ml/kg per side of injectable 0.2-0.3% ropivacaine with 0.5 mcg/kg dexmetomedine.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Evaluation of Bococizumab (PF-04950615; RN316) in Reducing the Occurrence of Major Cardiovascular Events in High Risk Subjects
Status: TERMINATED
Conditions: Cardiovascular Disease
Interventions: DRUG: bococizumab (PF-04950615)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Psychiatric Consultation-Liaison Intervention in Primary Care: A Pilot Study
Status: NOT_YET_RECRUITING
Conditions: Mental Health Issue|Depression/Anxiety|Quality of Life|Psychosomatic Disorders|Patients Lived Experiences|Doctor-Patient Relation|Collaboration
Interventions: OTHER: Intervention arm - Consultation-Liaison (CL) brief psychiatric intervention in primary care settings|OTHER: Control Arm - Treatment As Usual (TAU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study to Evaluate the Effects of Giving Interleukin-2 (IL-2) Plus Anti-HIV Therapy to HIV-Positive Patients With CD4 Cell Counts of at Least 350 Cells/mm3
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Aldesleukin
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: High-dose Chemotherapy as Second-line Drug Therapy for Relapsed Germ Cell Tumors
Status: RECRUITING
Conditions: Germ Cell Tumor
Interventions: DRUG: High-dose chemotherapy (TI- 2 cycles, CE- 3 cycles )
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of PDE5 Inhibition on Adipose Metabolism in Humans
Status: RECRUITING
Conditions: Obesity
Interventions: DRUG: Tadalafil 20 MG|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Novelty, Conformity and Trust in COVID-19 Vaccines
Status: COMPLETED
Conditions: Trust
Interventions: OTHER: RNA vaccine|OTHER: 20% adoption rate|OTHER: 40% adoption rate|OTHER: 60% adoption rate|OTHER: 80% adoption rate|OTHER: Conventional vaccine|OTHER: 0% adoption rate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Use of Biofeedback Training to Correct Abnormal Neuromechanical Pattern in Chronic Low Back Pain Patients
Status: COMPLETED
Conditions: Chronic Low Back Pain|Mechanical Low Back Pain
Interventions: OTHER: Biofeedback
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Prognosis of Lipid Reprogramming With Rosuvastatin, in Castrated Egyptian Prostate Cancer Patients
Status: COMPLETED
Conditions: Prostate Cancer Metastatic
Interventions: DRUG: Rosuvastatin 20mg|PROCEDURE: surgical castration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Behavioral Economics Applications to Geriatrics Leveraging EHRs
Status: COMPLETED
Conditions: Prostate Specific Antigen|Asymptomatic Bacteriuria|Type 2 Diabetes Mellitus
Interventions: BEHAVIORAL: Clinical decision support
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Dose Escalation Study of HBI-8000 in Combination With Paclitaxel and Trastuzumab in Women With Advanced or Metastatic HER2+ Breast Cancer
Status: WITHDRAWN
Conditions: Breast Cancer
Interventions: DRUG: HBI-8000|DRUG: Trastuzumab|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of the Treatment for Infant Iron Deficiency Anemia by Taking Lactoferrin and Ferralia
Status: COMPLETED
Conditions: Iron Deficiency Anemia
Interventions: OTHER: Standard infant fomula|OTHER: Low level LF infant formula|OTHER: High level LF infant formula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Laparoscopic Bariatric Surgery and Erector Spinae Plane Block
Status: COMPLETED
Conditions: Obesity|Postoperative Pain|Bariatric Surgery
Interventions: PROCEDURE: ESP block group|PROCEDURE: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Spectrum of Peripheral and Autonomic Neuropathies in Patients With aTTRwt Amyloidosis and Response to Patisiran Therapy
Status: RECRUITING
Conditions: Polyneuropathies|Wild Type ATTR Amyloidosis|Wild-Type Transthyretin-Related (ATTR)Amyloidosis|Wild-Type Transthyretin Cardiac Amyloidosis|Transthyretin Amyloidosis
Interventions: DRUG: patisiran
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT