pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Study to Evaluate the Safety and Preliminary Efficacy of IDCT, a Treatment for Symptomatic Lumbar Disc Degeneration
Status: COMPLETED
Conditions: Degenerative Disc Disease
Interventions: BIOLOGICAL: IDCT|PROCEDURE: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prevalence of Conjunctivitis and Indentification of Risk Factors With and Without Prophylactic Antibiotic Treatment in Neonates
Status: COMPLETED
Conditions: Ophthalmia Neonatorum
Interventions: OTHER: Rifamycine treatment|OTHER: whithout Rifamycine treatment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Lenalidomide, Fludarabine & Cyclophosphamide in Advanced Chronic Lymphocytic Leukemia Not Responding to Therapy
Status: COMPLETED
Conditions: Chronic Lymphocytic Leukemia
Interventions: DRUG: Cyclophosphamide|DRUG: Fludarabine phosphate|DRUG: Lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Interactive Alcohol Decision-Making Programs
Status: COMPLETED
Conditions: Heavy Drinking
Interventions: BEHAVIORAL: Empathic Statements/Reflections|BEHAVIORAL: Narrator Backstory|BEHAVIORAL: Male Narrator|BEHAVIORAL: Female Narrator|BEHAVIORAL: MI Techniques
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Exercise-induced Erythropoiesis: the Mechanistic of Angiotensin II
Status: RECRUITING
Conditions: Exercise Physiology
Interventions: DRUG: Valsartan 80 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: NeuroFLiPP: Parametric PET of Neuroinflammation in Fatty Liver Disease
Status: NOT_YET_RECRUITING
Conditions: Positron Emission Tomography
Interventions: DRUG: 18F-DPA-714|DRUG: 18F-FDG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Basal Plus GLP1-ra on Glycemic Variability in CKD
Status: RECRUITING
Conditions: Diabetes Mellitus|Diabetic Kidney Disease
Interventions: DRUG: Dulaglutide|DRUG: Insulin Degludec|DEVICE: Continuous glucose monitor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study With Idebenone in Patients With Chronic Vision Loss Due to Leber's Hereditary Optic Neuropathy (LHON)
Status: WITHDRAWN
Conditions: Leber's Hereditary Optic Neuropathy
Interventions: DRUG: Idebenone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose:
Clinical trial: Feeding the Critically Ill During Phases of Altered Redox Status
Status: COMPLETED
Conditions: Acute Respiratory Distress Syndrome|Oxidative Stress|Euthyroid Sick Syndromes|Systemic Inflammatory Response Syndrome
Interventions: OTHER: Jevity 1.5
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Percussion Device (PD) for Detection of Pneumothorax
Status: TERMINATED
Conditions: Pneumothorax
Interventions: DEVICE: Percussion Device (PD)|DEVICE: Ultrasound (US)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Cognitive Rehabilitation and Exposure Therapy for Geriatric Hoarding
Status: ENROLLING_BY_INVITATION
Conditions: Hoarding Disorder|Obsessive-Compulsive Disorder
Interventions: BEHAVIORAL: Cognitive Rehabilitation and Exposure/Sorting Therapy (CREST)|BEHAVIORAL: Case Management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immunotherapy With Bispecific CAR-T Cells for B-Cell Lymphoma, ALL and CLL
Status: UNKNOWN
Conditions: Leukemia|Lymphoma
Interventions: BIOLOGICAL: anti-CD19 anti-CD20 Bispecific CAR-T
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Impact of Germicidal Light (Indigo-Clean) on Intraoperative S. Aureus Exposure
Status: UNKNOWN
Conditions: Pathogen Transmission
Interventions: DEVICE: 405nm light
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Randomized, Double-masked, Multicenter, Controlled Study of Intravitreal KH902 in Patients With Neovascular AMD
Status: COMPLETED
Conditions: Neovascular Age-related Macular Degeneration
Interventions: BIOLOGICAL: intravitreal injection of KH902
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Diagnostic Effectiveness of Virtual Bronchoscopy
Status: COMPLETED
Conditions: Bronchogenic Carcinoma|Chronic Granulomatous Disease|Job's Syndrome|Mycobacterium Infection|Wegener's Granulomatosis
Interventions: DEVICE: virtual bronchoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Two-Part, Phase Ib/II, Open Label, Single-Arm, Multi-center Study to Evaluate the Safety and Efficacy of Varlitinib in Combination With Weekly Paclitaxel in EGFR/HER2 Co-expressing Advanced or Metastatic Gastric Cancer Patients
Status: COMPLETED
Conditions: Gastric Cancer
Interventions: DRUG: Variltinib, Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Perioperative MVT-5873, a Fully Human Monoclonal Antibody Against a CA 19-9 Epitope, for Operable CA 19-9 Producing Pancreatic Cancers, Cholangiocarcinomas, and Metastatic Colorectal Cancers
Status: COMPLETED
Conditions: Colon Cancer|Pancreatic Cancer|Cholangiocarcinoma|Metastatic Colon Carcinoma|Liver Metastasis
Interventions: DRUG: MVT-5873|PROCEDURE: pancreatectomy or hepatectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I Study of DS-2741a in Healthy Volunteers and Participants With Atopic Dermatitis
Status: TERMINATED
Conditions: Atopic Dermatitis
Interventions: DRUG: DS-2741a|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: D-dimer to Select Patients With First Unprovoked Venous Thromboembolism Who Can Have Anticoagulants Stopped at 3 Months
Status: COMPLETED
Conditions: Deep Vein Thrombosis|Pulmonary Embolism
Interventions: OTHER: Discontinue anticoagulant therapy (Negative d-dimer)|OTHER: Continue on anticoagulant therapy (positive d-dimer)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimising Pacing for Contractility 2
Status: RECRUITING
Conditions: Heart Failure, Systolic|Pacemaker
Interventions: DEVICE: Heart rate optimisation using force frequency data
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Switching From Anti-C5 Antibody Treatment to Iptacopan Treatment in Study Participants With Atypical Hemolytic Uremic Syndrome (aHUS)
Status: RECRUITING
Conditions: Atypical Hemolytic Uremic Syndrome
Interventions: DRUG: Iptacopan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Expanded Cord Blood in Patients in Need of an Allogeneic Stem Cell Transplant
Status: COMPLETED
Conditions: Hematologic Malignancy
Interventions: BIOLOGICAL: Transplantation of cord blood expanded with UM171
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect-site Concentration of Remifentanil for Smooth Induction With Desflurane
Status: COMPLETED
Conditions: Anesthesia
Interventions: DRUG: Remifentanil|DRUG: Desflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Evaluation of Fibrin Sealant 2 in Retroperitoneal or Intra-Abdominal Surgery
Status: COMPLETED
Conditions: Blood Loss, Surgical
Interventions: DRUG: Fibrin Sealant 2 (FS2)|DEVICE: Oxidized Regenerated Cellulose (Surgicel)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Patellar Taping on Proprioceptive Exercises in Young Women With Patellofemoral Pain Syndrome
Status: COMPLETED
Conditions: Anterior Knee Pain Syndrome
Interventions: OTHER: Intervention taping|OTHER: Placebo Taping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ARTISS a Single-centre Randomised Control Study
Status: COMPLETED
Conditions: Breast Neoplasms|Mammaplasty
Interventions: DRUG: ARTISS 4mL Fibrin Sealant Topical Solution (Frozen)|OTHER: no ARTISS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: LIKEST Study: Lipocet® in Adults With Primary Knee Osteoarthritis Grade 3-4
Status: COMPLETED
Conditions: Primary Knee Osteoarthritis Grade 3 - 4
Interventions: DIETARY_SUPPLEMENT: Lipocet® (food supplement)|DIETARY_SUPPLEMENT: Lipocet Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Fatigue as a Late Effect in Breast Cancer Survivors - is Acupuncture a Treatment Option?
Status: RECRUITING
Conditions: Fatigue|Depression, Anxiety|Insomnia|Hot Flashes|Quality of Life
Interventions: OTHER: Acupuncture; based on Tradidtional Chinese Medicine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Drug-Drug Interaction Study Between TAK-272 and Itraconazole, Digoxin or Midazolam
Status: COMPLETED
Conditions: Japanese Healthy Adult Males
Interventions: DRUG: TAK-272|DRUG: Digoxin|DRUG: Itraconazole|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SUPR-3D: Simple Unplanned Palliative Radiotherapy Versus 3D Conformal Radiotherapy for Patients With Bone Metastases
Status: RECRUITING
Conditions: Neoplasm Metastasis|Neoplastic Processes|Neoplasms|Pathologic Processes
Interventions: RADIATION: SUPR|RADIATION: VMAT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cisplatin and Ifosfamide Combined With Either Paclitaxel or Vinblastine in Treating Men With Progressive or Recurrent Metastatic Germ Cell Tumors
Status: TERMINATED
Conditions: Extragonadal Germ Cell Tumor|Testicular Germ Cell Tumor
Interventions: DRUG: cisplatin|DRUG: ifosfamide|DRUG: paclitaxel|DRUG: vinblastine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Evaluate the Safety and Efficacy of DWN12088 in Patients With IPF
Status: RECRUITING
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: DRUG: DWN12088|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Of PF-05212384 Plus FOLFIRI Versus Bevacizumab Plus FOLFIRI In Metastatic Colorectal Cancer
Status: TERMINATED
Conditions: Metastatic Colorectal Carcinoma
Interventions: DRUG: PF-05212384|DRUG: FOLFIRI regimen|BIOLOGICAL: Bevacizumab|DRUG: FOLFIRI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Crestal Bone Loss Around Short Dental Implants As Affected By Two Suprastructure Materials
Status: UNKNOWN
Conditions: Bone Loss
Interventions: OTHER: Vita Enamic (Hybrid dental ceramic)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Bioavailability of Blackberry Juice Anthocyanins
Status: COMPLETED
Conditions: Overweight and Obesity|Healthy
Interventions: DIETARY_SUPPLEMENT: Blackberry juice with 12% ethanol|DIETARY_SUPPLEMENT: Blackberry juice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Rapid Antidepressant Effects of Yohimbine in Major Depression
Status: COMPLETED
Conditions: Depression, Involutional|Major Depresssion
Interventions: DRUG: Yohimbine hydrochloride|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Sirolimus, Idarubicin, and Cytarabine in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Adult Acute Megakaryoblastic Leukemia (M7)|Adult Acute Monoblastic Leukemia (M5a)|Adult Acute Monocytic Leukemia (M5b)|Adult Acute Myeloblastic Leukemia With Maturation (M2)|Adult Acute Myeloblastic Leukemia Without Maturation (M1)|Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities|Adult Acute Myeloid Leukemia With Del(5q)|Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)|Adult Acute Myeloid Leukemia With t(16;16)(p13;q22)|Adult Acute Myeloid Leukemia With t(8;21)(q22;q22)|Adult Acute Myelomonocytic Leukemia (M4)|Adult Erythroleukemia (M6a)|Adult Pure Erythroid Leukemia (M6b)|Untreated Adult Acute Myeloid Leukemia
Interventions: DRUG: Sirolimus|DRUG: Idarubicin|DRUG: Cytarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Prospective, Multi-center, Randomized Controlled Blinded Trial Demonstrating the Safety and Effectiveness of VNS Therapy® System as Adjunctive Therapy Versus a No Stimulation Control in Subjects With Treatment-Resistant Depression
Status: RECRUITING
Conditions: Treatment Resistant Depression
Interventions: DEVICE: Vagus Nerve Stimulation (VNS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Data Collection From the CardiacSense1 and Other Modalities for Developing a System for Monitoring of Respiratory Rate
Status: UNKNOWN
Conditions: Respiratory Disease
Interventions: DEVICE: CardiacSense1 and capnograph Respiratory rate measurement
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Protective Effect Assessment of Foto Ultra Isdin Solar Allergy Fusion Fluid on the UVA Induced PLE
Status: COMPLETED
Conditions: Polymorphic Light Eruption
Interventions: DEVICE: Foto Ultra ISDIN® Solar Allergy Fusion Fluid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of High-dose Dual Therapy vs Bismuth-containing Quadruple Therapy for First-line Treatment of Hp Infection
Status: COMPLETED
Conditions: Helicobacter Pylori Infection
Interventions: DRUG: High-dose dual therapy (rabeprazole, amoxicillin)|DRUG: Bismuth-containing quadruple therapy (rabeprazole, tripotassium dicitrate bismuthate, metronidazole, tetracycline)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Study the Efficacy of Therapeutic Pulsed Ultrasound in the Treatment of Vitiligo: a Randomized, Intra-individual, Left-right Comparison Study
Status: COMPLETED
Conditions: Vitiligo
Interventions: DEVICE: HGM
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Patient Stratification and Treatment Response Prediction in Neuropharmacotherapy Using Hybrid Positron Emmission Tomography/Magnetic Resconance Imaging (PET/MR)
Status: UNKNOWN
Conditions: Major Depressive Disorder
Interventions: DIAGNOSTIC_TEST: PET/MR [11C]DASB|DRUG: Citalopram|DRUG: Escitalopram (Mirtazapine/Duloxetine/Venlafaxine)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of Pain Management After Surgery When Using Exparel in the Pediatric Population
Status: NOT_YET_RECRUITING
Conditions: Medial Patellofemoral Ligament (MPFL) Reconstruction|Sports Injuries in Children|Analgesia|Pain, Postoperative
Interventions: DRUG: Exparel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Validation of Kinocardiography, New Technology for Cardiac Linear and Torsional Contractility Measurement, to Assess Heart Failure Patient With Low Ejection Fraction
Status: COMPLETED
Conditions: Impaired Left Ventricular Ejection Fraction
Interventions: DEVICE: Kinocardiography
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Adaptive Optics Imaging of Outer Retinal Diseases
Status: RECRUITING
Conditions: Retinal Degeneration|Age-Related Macular Degeneration|Retinitis Pigmentosa|Hydroxychloroquine Retinopathy|Usher Syndromes|Late-Onset Retinal Degeneration|Cone Dystrophy|Cone Rod Dystrophy|Rod Cone Dystrophy|Rod Dystrophy
Interventions: DEVICE: Adaptive optics imaging
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Rilzabrutinib for the Treatment of Chronic Spontaneous Urticaria in Patients Who Remain Symptomatic Despite the Use of H1 Antihistamine
Status: COMPLETED
Conditions: Chronic Spontaneous Urticaria
Interventions: DRUG: rilzabrutinib|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Home-based Transcranial Direct Current Stimulation (tDCS) for Major Depressive Disorders (MDD)
Status: ACTIVE_NOT_RECRUITING
Conditions: Major Depressive Disorder
Interventions: DEVICE: tDCS intervention applied by Starstim device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Cyclophosphamide and Total Body Irradiation in Treating Patients Who Are Undergoing an Autologous Peripheral Stem Cell Transplant For Chronic Lymphocytic Leukemia
Status: COMPLETED
Conditions: Chronic Lymphocytic Leukemia
Interventions: BIOLOGICAL: filgrastim|DRUG: carmustine|DRUG: cyclophosphamide|DRUG: cytarabine|DRUG: dexamethasone|DRUG: etoposide|DRUG: fludarabine phosphate|DRUG: melphalan|PROCEDURE: bone marrow ablation with stem cell support|PROCEDURE: peripheral blood stem cell transplantation|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Inspiratory Muscle Training Combined With General Exercise Training in COPD
Status: UNKNOWN
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DEVICE: Inspiratory muscle training with Threshold by respironics|DEVICE: Sham Inspiratory muscle training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of Linaclotide in Patients With Chronic Constipation
Status: COMPLETED
Conditions: Chronic Constipation
Interventions: DRUG: Matching Placebo|DRUG: Linaclotide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Efficacy and Safety Study of Sodium Oligo-mannurarate (GV-971) Capsule for the Treatment of Alzheimer's Disease
Status: COMPLETED
Conditions: Mild to Moderate Alzheimer Disease|Cognitive Impairment
Interventions: DRUG: Sodium oligo-mannurarate 900mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Robot-assisted Upper-limb Exercise in Cervical SCI
Status: RECRUITING
Conditions: Cervical Vertebrae Injury
Interventions: BEHAVIORAL: Standard occupational therapy|DEVICE: Robot-assisted exercise using Amadeo device and Armeo Spring exoskeleton
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Omega-3 Supplementation and Vitreal VEGF Levels in Wet-AMD
Status: COMPLETED
Conditions: Exudative Age Related Macular Degeneration
Interventions: DIETARY_SUPPLEMENT: Anti-VEGF plus AREDS-2|DIETARY_SUPPLEMENT: Anti-VEGF plus AREDS-1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Evaluate Food Effect on the PK and Safety After Oral DWN12088 Administration in Healthy Adult Volunteers
Status: COMPLETED
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: DRUG: Diet A group|DRUG: Diet B group|DRUG: Diet C group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Erector Spinae Plane Block Versus Thoracic Paravertebral Block for Pain Control in Modified Radical Mastectomy
Status: COMPLETED
Conditions: Breast Surgery|Thoracic Paravertebral Block|Post-operative Pain Control|Erector Spinae Plane Block|Opioid Use
Interventions: PROCEDURE: Thoracic paravertebral block|PROCEDURE: Erector spinae plane Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Stent Malapposition and Neointimal Coverage on Optical coHerence Tomography at Post-procedure and 3 Months After Platinum Chromium Alloy Of the Element™ Stent Implantation
Status: UNKNOWN
Conditions: Coronary Artery Disease
Interventions: DEVICE: Promus Element everolimus eluting coronary stent|DEVICE: Xience Prime everolimus eluting coronary stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Seroquel® Combined With Cognitive Remediation Therapy to Conventional Treatment in Patients With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Quetiapine fumarate|DRUG: conventional treatment for schizophrenia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Continuous Femoral Nerve Block With Modulation of Depth of Anesthesia on Prognosis of Patients Receiving Total Knee Arthroplasty
Status: UNKNOWN
Conditions: Pain Management|Sedation|Peripheral Nerve Block|Total Knee Arthroplasty
Interventions: PROCEDURE: peri-operative continuous femoral nerve block with light sedation|PROCEDURE: post-operative continuous femoral nerve block|DRUG: lidocaine|DEVICE: ultrasound|DEVICE: insulated needle (Contiplex B Braun, Melsungen, Germany)|DRUG: ropivacaine|DRUG: saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of Tri-weekly TJ Versus Weekly TJ for Stage II-IV Mullerian Carcinoma
Status: COMPLETED
Conditions: Epithelial Ovarian Cancer|Primary Peritoneal Cancer|Fallopian Tube Cancer
Interventions: DRUG: Paclitaxel+Carboplatin|DRUG: Paclitaxel+Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: AgION Catheter for Preventing Catheter-Related Bloodstream Infections
Status: COMPLETED
Conditions: Catheter-Related Infections
Interventions: DEVICE: Umbilical catheterization (AgION )|DEVICE: Umbilical catheterization (ArgyleTM)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Prednisolone Versus Vigabatrin in the First-line Treatment of Infantile Spasms
Status: WITHDRAWN
Conditions: Infantile Spasms
Interventions: DRUG: Prednisolone|DRUG: Vigabatrin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Research Study Looking at Similarity Between Once-weekly Semaglutide Versions for Different Injection Pens
Status: COMPLETED
Conditions: Healthy Volunteers|Diabetes Mellitus, Type 2
Interventions: DRUG: Semaglutide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 3, Febuxostat, Allopurinol and Placebo-Controlled Study in Gout Subjects.
Status: COMPLETED
Conditions: Gout
Interventions: DRUG: Febuxostat|DRUG: Febuxostat|DRUG: Febuxostat|DRUG: Allopurinol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Double Blind Efficacy and Safety Study of Flexible-Dose vs Low-Dose Q8003 After Undergoing Primary Unilateral Total Knee Arthroplasty
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: Flexible dose Q8003 (morphine sulfate and oxycodone hydrochloride)|DRUG: Low dose Q8003 (morphine sulfate and oxycodone hydrochloride)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Quantifying tACS-driven Improvement of Working Memory in Depression
Status: NOT_YET_RECRUITING
Conditions: Depression
Interventions: OTHER: theta tACS stimulation|OTHER: sham tACS stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy and Safety of Neoadjuvant Surufatinib for Patients With Salivary Gland Carcinomas
Status: UNKNOWN
Conditions: Salivary Gland Carcinomas
Interventions: DRUG: Surufatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of the Addition of a Specific and Personalized Body Approach by Osteopathic Treatment in the Care of Adolescents With Anorexia Nervosa.
Status: UNKNOWN
Conditions: Anorexia Nervosa|Osteopathic Medicine
Interventions: OTHER: Osteopathic treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Fenofibrate on Endothelial Progenitor Cells in Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetic Retinopathy
Interventions: DRUG: Fenofibrate 145 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Phase 1 Study of ATR-101 in Subjects With Advanced Adrenocortical Carcinoma
Status: COMPLETED
Conditions: Adrenocortical Carcinoma|Adrenal Cancer|ACC
Interventions: DRUG: ATR-101
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Hydrocolloid to Prevent Nasal Injuries in Preterm Infants
Status: COMPLETED
Conditions: Pressure Injury
Interventions: OTHER: Hidrocolloid Bant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Reduced Intensity Conditioning for Non-Malignant Disorders Undergoing UCBT, BMT or PBSCT
Status: RECRUITING
Conditions: Primary Immunodeficiency (PID)|Congenital Bone Marrow Failure Syndromes|Inherited Metabolic Disorders (IMD)|Hereditary Anemias|Inflammatory Conditions|Systemic Juvenile Idiopathic Arthritis (sJIA)
Interventions: DRUG: Hydroxyurea|DRUG: Alemtuzumab|DRUG: Fludarabine|DRUG: Melphalan|DRUG: Thiotepa
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mucopolysaccharidosis (MPS) I, II, and VI Screening in a High-Risk Population With Previous Surgical Repair or Presence of Inguinal and/or Umbilical Hernia in Combination With Pediatric ENT Surgery (The HATT Project)
Status: TERMINATED
Conditions: Mucopolysaccharidosis (MPS)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: ILT-101 in Patients With Active Moderate to Severe Systemic Lupus Erythematosus (SLE)
Status: COMPLETED
Conditions: Systemic Lupus Erythematosus
Interventions: DRUG: ILT-101|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: AZD7325 Multiple Ascending Dose Study
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: AZD7325
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: GCF HIF-1α, VEGF and TNF-α Levels in G-AgP Patients Before and After Periodontal Treatment.
Status: COMPLETED
Conditions: Aggressive Periodontitis, Generalized|Periodontal Health
Interventions: PROCEDURE: Non-surgically performed scaling and root planing
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sequential or Concurrent Chemoradiotherapy in Patients With Locoregionally Advanced NPC
Status: RECRUITING
Conditions: Nasopharyngeal Carcinoma
Interventions: DRUG: gemcitabine and cisplatin (Induction and adjuvant chemotherapy)|RADIATION: IMRT|DRUG: gemcitabine and cisplatin (Induction chemotherapy)|RADIATION: IMRT and concurrent cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prenatal Behavioral Intervention to Prevent Maternal Cytomegalovirus (CMV) in Pregnancy
Status: RECRUITING
Conditions: Maternal Cytomegalovirus Infections|Cytomegalovirus Congenital
Interventions: BEHAVIORAL: CMV Risk-Reduction Intervention|BEHAVIORAL: Stress Reduction Messaging
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: SHR-1210 Combined With Epirubicin in the Treatment of Extensive Disease Small Cell Lung Cancer
Status: UNKNOWN
Conditions: Small Cell Lung Cancer Extensive Stage
Interventions: DRUG: Epirubicin plus SHR1210
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Congenital Telangiectasia (Coat's Disease) With Open-label Anecortave Acetate (15mg.)
Status: COMPLETED
Conditions: Coat's Disease
Interventions: DRUG: anecortave acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Posterior Tibial Nerve PRF for Diabetic Neuropathic Pain
Status: ACTIVE_NOT_RECRUITING
Conditions: Diabetic Neuropathies, Painful|Diabetic Neuropathy Peripheral
Interventions: PROCEDURE: ultrasound-guided posterior tibial nerve pulsed radiofrequency
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cognitive Benefits of Treating Sleep Apnea in Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson's Disease|Sleep Disordered Breathing
Interventions: DEVICE: Continuous positive airway pressure (CPAP)|DEVICE: Placebo CPAP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MARS MRI in Revision THA With a Ceramic Femoral Head and Titanium Sleeve
Status: RECRUITING
Conditions: Arthroplasty, Replacement, Hip
Interventions: DIAGNOSTIC_TEST: MARS MRI|DIAGNOSTIC_TEST: Titanium Labs|DIAGNOSTIC_TEST: Cobalt Labs|DIAGNOSTIC_TEST: Chromium Labs
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Long-term Safety and Effectiveness of OROS Methylphenidate HCl in Children With Attention Deficit Hyperactivity Disorder
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: DRUG: methylphenidate HCl
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Adverse Long-term Effects in Young Adult Survivors of Acute Leukemia
Status: UNKNOWN
Conditions: Leukemia, Myeloid, Acute|Acute Lymphoid Leukemia
Interventions: OTHER: Blood sample|OTHER: Electrocardiogram
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety, Tolerability, and Efficacy of IONIS-GHR-LRx in Participants With Acromegaly Being Treated With Long-acting Somatostatin Receptor Ligands
Status: COMPLETED
Conditions: Acromegaly
Interventions: DRUG: IONIS-GHR-LRx|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Alirocumab (SAR236553/REGN727) Versus Placebo on Top of Lipid-Modifying Therapy in Patients With Heterozygous Familial Hypercholesterolemia Not Adequately Controlled With Their Lipid-Modifying Therapy
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DRUG: Alirocumab|DRUG: Placebo (for alirocumab)|DRUG: Lipid Modifying Therapy (LMT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fixation of Unstable Distal Radius Fractures
Status: COMPLETED
Conditions: Distal Radius Fractures
Interventions: DEVICE: Intramedullary Radius Fixation (Micronail)|PROCEDURE: Volar Plate Fixation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Posterior Wall Substrate Modification Using Irreversible Electroporation for Paroxysmal Atrial Fibrillation
Status: NOT_YET_RECRUITING
Conditions: Atrial Fibrillation Paroxysmal
Interventions: PROCEDURE: Pulmonary Vein Isolation alone|PROCEDURE: Pulmonary Vein Isolation and Left atrial Posterior Wall Isolation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 3 Study of Tramadol Hydrochloride/Acetaminophen SR Tab. & Tramadol Hydrochloride/Acetaminophen Tab. in Low Back Pain Patients
Status: COMPLETED
Conditions: Low Back Pain
Interventions: DRUG: Tramadol hydrochloride/Acetaminophen Tab.|DRUG: Tramadol hydrochloride/Acetaminophen SR Tab.
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose:
Clinical trial: A Randomized Trial of Interim Methadone and Patient Navigation Initiated in Jail
Status: COMPLETED
Conditions: Opioid Use Disorder
Interventions: DRUG: Methadone|BEHAVIORAL: Patient Navigation|BEHAVIORAL: Enhanced Treatment as Usual (ETAU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Catheter-Directed Thrombolysis Versus Anticoagulation Monotherapy in Intermediate-High Risk PE
Status: TERMINATED
Conditions: Pulmonary Embolism|Pulmonary Thromboembolisms|Embolism, Pulmonary|Right Ventricular Dysfunction
Interventions: PROCEDURE: Conventional catheter-directed thrombolysis (CDT) with recombinant tissue plasminogen activator (rtPA)|DRUG: Enoxaparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Continuous Glucose Monitoring to Reduce Hypoglycemia and Improve Safety After Gastric Surgery
Status: COMPLETED
Conditions: Hypoglycemia, Reactive|Hypoglycemia
Interventions: DEVICE: Dexcom CGM masked|DEVICE: Dexcom CGM unmasked
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Evaluate the Efficacy and Safety of JLP-2002 on Symptoms of Overactive Bladder
Status: COMPLETED
Conditions: Overactive Bladder
Interventions: DRUG: JLP-2002 A mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Salvia Hispanica Seed in Reducing Risk of Disease Recurrence in Patients With Non-Hodgkin Lymphoma
Status: COMPLETED
Conditions: Adult Nasal Type Extranodal NK/T-Cell Lymphoma|Adult T-Cell Leukemia/Lymphoma|Anaplastic Large Cell Lymphoma|Angioimmunoblastic T-Cell Lymphoma|B Lymphoblastic Leukemia/Lymphoma|Blastic Plasmacytoid Dendritic Cell Neoplasm|Burkitt Leukemia|Central Nervous System Lymphoma|Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma|Diffuse Large B-Cell Lymphoma|Enteropathy-Associated T-Cell Lymphoma|Extranodal Marginal Zone Lymphoma of Mucosa-Associated Lymphoid Tissue|Grade 1 Follicular Lymphoma|Grade 2 Follicular Lymphoma|Grade 3 Follicular Lymphoma|Hepatosplenic T-Cell Lymphoma|Lymphoplasmacytic Lymphoma|Mantle Cell Lymphoma|Mediastinal (Thymic) Large B-Cell Lymphoma|Mycosis Fungoides|Nasal Type Extranodal NK/T-Cell Lymphoma|Nodal Marginal Zone Lymphoma|Peripheral T-Cell Lymphoma, Not Otherwise Specified|Post-Transplant Lymphoproliferative Disorder|Primary Cutaneous Anaplastic Large Cell Lymphoma|Primary Effusion Lymphoma|Sezary Syndrome|Splenic Marginal Zone Lymphoma|Subcutaneous Panniculitis-Like T-Cell Lymphoma|Systemic Anaplastic Large Cell Lymphoma|T Lymphoblastic Leukemia/Lymphoma|Transformed Recurrent Non-Hodgkin Lymphoma
Interventions: OTHER: Laboratory Biomarker Analysis|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration|DIETARY_SUPPLEMENT: Salvia hispanica Seed
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Intralesional Cryosurgery for Basal Cell Carcinoma - a Feasibility Study
Status: UNKNOWN
Conditions: Basal Cell Carcinoma (BCC)
Interventions: PROCEDURE: Intralesional cryotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Standard Versus Intensive Monitoring After Myocardial Infarction Looking for Atrial Fibrillation
Status: UNKNOWN
Conditions: Atrial Fibrillation New Onset|Myocardial Infarction
Interventions: DIAGNOSTIC_TEST: 30-day ambulatory cardiac event monitor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of Cetuximab, Oxaliplatin, 5-FU/LV Versus Oxaliplatin, 5-FU/LV in Patients With Previously Treated Metastatic, EGFR-Positive Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: BIOLOGICAL: cetuximab|DRUG: oxaliplatin|DRUG: leucovorin|DRUG: 5-fluorouracil|DRUG: 5-fluorouracil|BIOLOGICAL: cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CART-EGFRvIII + Pembrolizumab in GBM
Status: COMPLETED
Conditions: Glioblastoma
Interventions: BIOLOGICAL: CART-EGFRvIII T cells|BIOLOGICAL: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Patient Preference for Home Administration of Fixed-Dose Combination of Pertuzumab and Trastuzumab for Subcutaneous Administration in Participants With Early or Locally Advanced/Inflammatory HER2-Positive Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Early Breast Cancer|Locally Advanced Breast Cancer|Inflammatory Breast Cancer
Interventions: DRUG: Fixed Dose Combination of Pertuzumab and Trastuzumab for Subcutaneous Use (PH FDC SC)|DRUG: Pertuzumab IV|DRUG: Trastuzumab IV|DRUG: Trastuzumab Emtansine|DRUG: Investigator's Choice of Chemotherapy|PROCEDURE: Surgery|RADIATION: Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Midfacial Gingival Margin Changes Following Immediate Implants.
Status: COMPLETED
Conditions: Customized Healing Abutment Bone Grafts Connective Tissue Graft Immediate Implant Placement
Interventions: PROCEDURE: Connective tissue graft /Bone graft/ Customized HA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Developing Low-Cost Universal Malnutrition Screening for Low Income Countries - the MAMMS Trial
Status: UNKNOWN
Conditions: Child Malnutrition
Interventions: OTHER: Maternal Administered Malnutrition Monitoring System (MAMMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Orebro Musculoskeletal Screening Questionnaire-12
Status: ACTIVE_NOT_RECRUITING
Conditions: Musculoskeletal Injury
Interventions: OTHER: Orebro Musculoskeletal Screening Questionnaire-12|OTHER: Visual Analog Scale|OTHER: The Tampa Scale of Kinesiophobia|OTHER: Short Form-12 (SF-12)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phase I Study of Corticosteroid Treatment of Ill-Defined Choroidal Neovascularization in Age-Related Macular Degeneration
Status: COMPLETED
Conditions: Choroidal Neovascularization|Macular Degeneration
Interventions: DRUG: Corticosteroid
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: ABT-450/Ritonavir/ABT-267 (ABT-450/r/ABT-267) and ABT-333 in Treatment-Naïve and Treatment-Experienced, Non-Cirrhotic Asian Adults With Subgenotype 1b Chronic Hepatitis C Virus (HCV) Infection
Status: COMPLETED
Conditions: Hepatitis C Virus (HCV)
Interventions: DRUG: ombitasvir/paritaprevir/ritonavir and dasabuvir|DRUG: Placebo for ombitasvir/paritaprevir/ritonavir and dasabuvir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An Investigational Scan (MRI) in Imaging Patients With Newly-Diagnosed or Recurrent Thymoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Recurrent Malignant Thymoma|Thymoma
Interventions: PROCEDURE: Diaphragm Fluoroscopy|PROCEDURE: Magnetic Resonance Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Diflomotecan (BN80915) Administered Once Every 3 Weeks in Treating Patients With Sensitive Small Cell Lung Cancer (SCLC)
Status: COMPLETED
Conditions: Small Cell Lung Cancer
Interventions: DRUG: Diflomotecan (BN80915)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Morning Versus Evening Perindopril on Blood Pressure Control in People With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Hypertension
Interventions: DRUG: Perindopril Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Helping Osteoarthritis Patients to Walk With NSAID
Status: RECRUITING
Conditions: Osteoarthritis, Knee|Osteoarthritis, Hip|Chronic Pain
Interventions: DRUG: therapeutic program including intermittent drug intake and multimodal rehabilitation program
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: L-Arginine Supplementation and Exercise; L-Arginine Supplementation and Renal Function
Status: COMPLETED
Conditions: Heart Transplantation
Interventions: DRUG: 12 g of L-arginine glutamate during 6 weeks twice a day
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Study of Propylene Glycol-Free Melphalan HCl for Myeloablative Conditioning in Multiple Myeloma Patients Undergoing Autologous Transplantation
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Melphalan HCl for injection (propylene glycol free)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exercise Timing and Gestational Diabetes
Status: COMPLETED
Conditions: Pregnancy Related|Diabetes|Diabete Mellitus|Type 2 Diabetes|Pre-diabetes|Exercise
Interventions: BEHAVIORAL: 30-minute walking intervention|BEHAVIORAL: 10-minute
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Theta Burst Stimulation for Compulsive Behavior Non-invasive Brain Stimulation Study
Status: COMPLETED
Conditions: Compulsive Behavior|Obsessive-Compulsive Disorder
Interventions: BEHAVIORAL: Habit Override Practice|OTHER: Transcranial Magnetic Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE