pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Re-licensing Study to Assess the Efficacy of Inflexal V Formulated With WHO Recommended 2008/2009 Influenza Virus Strains for the Northern Hemisphere
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Inflexal V
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hydroxychloroquine Versus Placebo: Impact on Thrombotic Relapse in Primary Antiphospholipid Syndrome
Status: UNKNOWN
Conditions: Primary Antiphospholipid Syndrome
Interventions: DRUG: Hydroxychloroquine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Ramipril in Suppressing ST2 Expression in Rheumatic Mitral Stenosis Patients
Status: UNKNOWN
Conditions: Rheumatic Heart Disease|Mitral Stenosis|Rheumatic Mitral Stenosis|Fibrosis; Heart|ACE Inhibitor
Interventions: DRUG: Placebos|DRUG: Ramipril 5Mg Oral Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Pulmonary Telerehabilitation and Telemonitoring for Patients With Chronic Respiratory Diseases
Status: RECRUITING
Conditions: COPD|Interstitial Lung Disease
Interventions: OTHER: Exercise program (virtual/remote)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Efficacy of Alleance® (Atropine Sulfate 0.01%) as a Treatment to Delay Myopia and Axial Ocular Elongation in Children.
Status: NOT_YET_RECRUITING
Conditions: Myopia|Myopia, Progressive
Interventions: DRUG: Alleance®|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 2, Open-Label, Multi-Dose Study of Panhematin in Patients With MDS
Status: TERMINATED
Conditions: Myelodysplastic Syndrome
Interventions: DRUG: Panhematin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non-Invasive Quantification of Liver Health in NASH (N-QUAN)
Status: RECRUITING
Conditions: NASH - Nonalcoholic Steatohepatitis
Interventions: DIAGNOSTIC_TEST: Liver Multi Scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Misoprostol Versus Active Management of Labour in CS
Status: COMPLETED
Conditions: Cesarean Section
Interventions: DRUG: Misoprostol + syntocinon and using extra uterotonic drugs when needed ; methergine|DRUG: Syntocinon and using extra uterotonic drugs when needed ; methergine carboprost
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: House Calls and Peer Mentorship
Status: COMPLETED
Conditions: Chronic Kidney Disease|End-Stage Renal Disease
Interventions: BEHAVIORAL: House Call|BEHAVIORAL: Peer Mentorship
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: PREPARE：Assessing the Safety and Efficacy of Radial Versus Femoral Approach PCI
Status: WITHDRAWN
Conditions: Transradial-transfemoral Coronary Interventions Comparison
Interventions: PROCEDURE: transfemoral intervention (TFI)|PROCEDURE: Transradial intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of BIIL 284 BS in Adult Patients With Active Rheumatoid Arthritis
Status: COMPLETED
Conditions: Arthritis, Rheumatoid
Interventions: DRUG: BIIL 284 BS low dose|DRUG: BIIL 284 BS medium dose|DRUG: BIIL 284 BS high dose|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Folic Acid and Zinc Supplementation Trial (FAZST)
Status: COMPLETED
Conditions: Pregnancy|Live Birth|Spontaneous Abortion
Interventions: DIETARY_SUPPLEMENT: 5 mg folic acid and 30 mg elemental zinc|DRUG: Placebo Comparator: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Vascutek Hybrid Graft for Use in the Replacement of the Aortic Arch and Concomitant Treatment of an Aneurysm/Dissection of the Descending Aorta in the Frozen Elephant Trunk Procedure
Status: COMPLETED
Conditions: Aneurysmal Disease of the Ascending Aorta, the Arch and the Proximal Descending Aorta
Interventions: DEVICE: Vascutek Hybrid Graft
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gemcitabine Plus Docetaxel in Treating Patients With Unresectable or Metastatic Liver Cancer
Status: COMPLETED
Conditions: Liver Cancer
Interventions: DRUG: docetaxel|DRUG: gemcitabine hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Response of FeNO, Small Airway Dysfunction and Lung Heterogeneity to 2-week Montelukast Treatment in Asthmatic Children.
Status: COMPLETED
Conditions: Mild Persistent Asthma
Interventions: DRUG: Montelukast to placebo|DRUG: Placebo to montelukast
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of Vedolizumab With and Without Upadacitinib in Adults With Crohn's Disease
Status: NOT_YET_RECRUITING
Conditions: Crohn's Disease
Interventions: DRUG: Vedolizumab|DRUG: Upadacitinib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinic Trial to Evaluate the Safety and Immunogenicity of Combined Immunization of sIPV and DTaP
Status: UNKNOWN
Conditions: Vaccination
Interventions: BIOLOGICAL: Sabin-IPV and DTaP|BIOLOGICAL: Sabin-IPV|BIOLOGICAL: DTaP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects on Recovery of Postoperative Gastrointestinal Function With Multimodal Analgesia
Status: NOT_YET_RECRUITING
Conditions: Gastrointestinal Recovery
Interventions: DRUG: Tenoxicam|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Effects of Complex Decongestive Therapy on Proprioception, Balance and Tactile Sense
Status: RECRUITING
Conditions: Lymphedema of Leg|Sensitisation|Balanced|Therapy-Associated Cancer
Interventions: OTHER: complex decongestive therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evidence-based Stimulation Trial With Human rFSH in Europe and Rest of World 1
Status: COMPLETED
Conditions: Infertility
Interventions: DRUG: Follitropin Delta (FE 999049)|DRUG: Follitropin Alfa (GONAL-F)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Selective Cytopheretic Device (SCD) for Acute Kidney Injury (AKI) and Hepatorenal Syndrome (HRS) Type I
Status: RECRUITING
Conditions: Acute Kidney Injury|Hepatorenal Syndrome
Interventions: DEVICE: Selective Cytopheretic Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acceptance and Efficacy of a Digital Application Among Parents to Control Early Childhood Caries
Status: COMPLETED
Conditions: Early Childhood Caries|Oral Hygiene|Oral Health
Interventions: OTHER: FU-APP|OTHER: Oral health recommendations
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Effects of Soy Protein on Body Composition and General Health in Healthy Children
Status: COMPLETED
Conditions: Generally Healthy Kids Consumption Soy Protein Foods as Part of Daily Diet
Interventions: OTHER: Soy protein containing foods|BEHAVIORAL: Dietary Guidance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: ACTIV-2: A Study for Outpatients With COVID-19
Status: COMPLETED
Conditions: Coronavirus|Covid19
Interventions: BIOLOGICAL: bamlanivimab 7000mg|BIOLOGICAL: BRII-196+BRII-198|BIOLOGICAL: AZD7442 (IV)|BIOLOGICAL: AZD7442 (IM)|DRUG: SNG001|DRUG: Camostat|BIOLOGICAL: BMS-986414 + BMS-986413|BIOLOGICAL: SAB-185 (3,840 Units/kg)|BIOLOGICAL: SAB-185 (10,240 Units/kg)|DRUG: CASIRIVIMAB + IMDEVIMAB|DRUG: Placebo for Bamlanivimab 7000mg|DRUG: Placebo for Bamlanivimab 700mg|DRUG: Placebo for BRII-196+BRII-198|DRUG: Placebo for SNG001|DRUG: Placebo for Camostat|DRUG: Placebo for SAB-185 (low dose)|DRUG: Placebo for BMS-986414 + BMS-986413|DRUG: Placebo for AZD7442 (IV)|DRUG: Placebo for AZD7442 (IM)|DRUG: Placebo for SAB-185 (high dose)|BIOLOGICAL: bamlanivimab 700mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Open Label Extension (OLE) of the TDF2 Study, Botswana
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Tenofovir Disoproxil Fumarate 300 mg + Emtricitabine 200 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Adductor Canal Nerve Block Compared to a Simulated Block on Quadriceps Strength Following Knee Arthroplasty
Status: COMPLETED
Conditions: Knee Arthroplasty
Interventions: DEVICE: Adductor canal femoral nerve block|DEVICE: Simulated nerve blockade
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Elimination of VPB With Ablation Versus Anti-arrhythmic Drug Treatment
Status: COMPLETED
Conditions: Ventricular Premature Beats
Interventions: DRUG: Sotalol|DRUG: Flecainide and verapamil|PROCEDURE: Catheter ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Subjective Wearing Experience of the Total30 for Astigmatism Lens Among Satisfied Biofinity Toric Lens Wearers
Status: COMPLETED
Conditions: Astigmatism
Interventions: DEVICE: Dailies Total1® contact lenses for astigmatism (T30fA)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phlebotomy to Prevent Blood Loss in Major Hepatic Resections
Status: COMPLETED
Conditions: Liver Neoplasms|Hepatectomy
Interventions: PROCEDURE: Phlebotomy|DEVICE: Citrated whole blood collection bag
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of AS1411 Combined With Cytarabine in the Treatment of Patients With Primary Refractory or Relapsed Acute Myeloid Leukemia
Status: TERMINATED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: AS1411|DRUG: Cytarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Saginil in vs. Placebo for Gynecologic Oncology Patients Affected by Vaginitis
Status: UNKNOWN
Conditions: Vaginitis
Interventions: DRUG: Adelmidrol vaginal gel|DRUG: Placebo vaginal gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Multi-Centered Study of the Long-Term Effect of Salmeterol and Albuterol in Cystic Fibrosis
Status: SUSPENDED
Conditions: Cystic Fibrosis
Interventions: DRUG: Salmeterol|DRUG: Albuterol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Effect of Pulmonary Rehabilitation Among Post-COVID-19 Patients in a Tertiary Care Hospital in Bangladesh
Status: ACTIVE_NOT_RECRUITING
Conditions: Pulmonary Pathology
Interventions: BEHAVIORAL: Pulmonary Rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Bronchial Blocker for One-lung Ventilation in Cardiac Surgery
Status: UNKNOWN
Conditions: Complication of Ventilation Therapy|Intubation Complication|Postoperative; Dysfunction Following Cardiac Surgery
Interventions: DEVICE: double-lumen endotracheal tube (DLT group)|DEVICE: endobronchial blocker (BB group)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Perioperative Oxaliplatin With S-1 Combined H. Pylori Eradication in the Management of Locally Advanced Gastric Cancer
Status: NOT_YET_RECRUITING
Conditions: Chemotherapy Effect
Interventions: DRUG: Oxaliplatin With S-1 (SOX) Combined H. Pylori Eradication (Amoxicillin + clarithromycin + omeprazole + colloidal bismuth subcitrate)|DRUG: Oxaliplatin With S-1 （SOX）
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of a Nanofat-seeded Biological Scaffold in Healing Lower Limb Surgical Defects
Status: WITHDRAWN
Conditions: Wound of Skin|Non-melanoma Skin Cancer|Skin Graft Complications|Wound of Lower Leg|Wound of Knee
Interventions: OTHER: Nanofat-seeded biological scaffold on surgical defect
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Analysis of Capillary Retinal and Papillary Vascularization in Patients With Amyotrophic Lateral Sclerosis - CAPISLA
Status: UNKNOWN
Conditions: Amyotrophic Lateral Sclerosis
Interventions: OTHER: angiographic optical coherence tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effects of Aerobic Training and Neurodynamics to Prevent Fall and Improve Balance in Patients With Diabetic Neuropathy
Status: RECRUITING
Conditions: Diabetic Neuropathies
Interventions: OTHER: Neurodynamics|OTHER: Aerobic training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of BAK on the Blood Aqueous Barrier of Pseudophakic Patients
Status: COMPLETED
Conditions: Dry Eye Syndromes
Interventions: DRUG: Hydroxypropylmethylcellulose|DRUG: Carboxymethylcellulose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: PSMA Therapy and Immunotherapy in Kidney Cancer
Status: NOT_YET_RECRUITING
Conditions: Metastatic Renal Cell Carcinoma|Metastatic Clear Cell Renal Cell Carcinoma
Interventions: DRUG: Pembrolizumab|DRUG: 177Lu-PNT2002|DRUG: (F-18)-DCFPyL
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PCI-24781 in Combination With Doxorubicin to Treat Sarcoma
Status: COMPLETED
Conditions: Sarcoma
Interventions: DRUG: PCI-24781|DRUG: Doxorubicin|DRUG: GCSF
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Proof-of-concept Study on Rapid Immune Modulating Effects
Status: UNKNOWN
Conditions: Immune Surveillance
Interventions: DIETARY_SUPPLEMENT: Transfer factor from colostrum ultrafiltrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Respiratory and Physical Therapy in Patients With Associated Pulmonary Arterial Hypertension (APAH) With Congenital Heart Defects
Status: RECRUITING
Conditions: Pulmonary Arterial Hypertension|Eisenmenger Syndrome
Interventions: OTHER: respiratory and exercise therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Treatment of Heroin and Cocaine With Methadone Maintenance and Contingency Management
Status: COMPLETED
Conditions: Opiate-Related Disorders|Cocaine-Related Disorders
Interventions: DRUG: Methadone|BEHAVIORAL: Contingency Management|DRUG: Methadone dose|BEHAVIORAL: Contingency Management/Noncontingent Incentives
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sitagliptin (DPP-4 Inhibitor) and NPH Insulin in Patients With T2D
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: sitagliptin|DRUG: NPH insulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Ease of Application, Removal, and Comfort of Gradusox™
Status: UNKNOWN
Conditions: Ease of Applying and Removing, and Comfort, of Compression Stockings
Interventions: DEVICE: Graduated compression stockings
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Human-Prosthetic Interaction: Brain & Technology After Lower-Limb Loss
Status: RECRUITING
Conditions: Lower Limb Amputation Below Knee (Injury)
Interventions: DEVICE: Prosthetic device (Lunaris)|OTHER: No prosthetic device|DEVICE: Prosthetic device (Sach foot)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Adjuvant Benefit of NMES to Supervised Exercise in Patients With IC
Status: COMPLETED
Conditions: Intermittent Claudication|Peripheral Vascular Disease|Lower Limb Arterial Disease
Interventions: DEVICE: Revitive IX
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Buprenorphine for Treatment of Neonatal Abstinence Syndrome in Infants With In Utero Exposure to Benzodiazepines
Status: COMPLETED
Conditions: Neonatal Abstinence Syndrome
Interventions: DRUG: oral morphine|DRUG: sublingual buprenorphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Application of 68Ga-DOTA-NT-20.3 in the Early Diagnosis of Pancreatic Ductal Adenocarcinoma
Status: COMPLETED
Conditions: Pancreatic Ductal Adenocarcinoma
Interventions: RADIATION: 68Ga-DOTA-NT-20.3
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Translating Neuroprediction Into Precision Medicine Via Brain Priming
Status: TERMINATED
Conditions: Autism Spectrum Disorder
Interventions: DRUG: Oxytocin|BEHAVIORAL: Pivotal Response Treatment|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study on Evaluating the Geroprotective Effect of Metformin
Status: NOT_YET_RECRUITING
Conditions: Metformin|Aging
Interventions: DRUG: Metformin Hydrochloride tablet|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: DL6049 vs CosmoPlast in the Treatment of Nasolabial Fold Wrinkles
Status: COMPLETED
Conditions: Nasolabial Fold Wrinkles
Interventions: DEVICE: DL6049 (injectable poly-L-lactic acid)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Direct Instruction Language for Learning in Autism Spectrum Disorder
Status: COMPLETED
Conditions: Autism Spectrum Disorder|Moderate Language Delay
Interventions: BEHAVIORAL: Direct Instruction-Language for Learning (DI-LL) via telehealth (e.g., Zoom or WebEx)|BEHAVIORAL: Standard of care delivered via telehealth (e.g., Zoom or WebEx)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of Irinotecan Liposome Combination Therapy for Advanced Gastric Cancer
Status: NOT_YET_RECRUITING
Conditions: Gastric Cancer
Interventions: DRUG: Irinotecan Hydrochloride Liposome Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Palifosfamide-tris in Combination With Carboplatin and Etoposide in Chemotherapy Naïve Patients With Extensive-Stage Small Cell Lung Cancer (The MATISSE Study)
Status: UNKNOWN
Conditions: Extensive-Stage Small Cell Lung Cancer
Interventions: DRUG: Carboplatin|DRUG: Palifosfamide-tris|DRUG: Etoposide|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vectored Thermal Pulsation, Intense Pulsed Light, and Eyelid Warm Compress Therapies for MGD
Status: ACTIVE_NOT_RECRUITING
Conditions: Meibomian Gland Dysfunction
Interventions: DEVICE: Vectored thermal pulsation (VTP) therapy|DEVICE: Intense pulsed light with meibomian gland expression (IPL+MGX) therapy|BEHAVIORAL: Eyelid Warm Compress Therapy (EW)|DRUG: Topical eye drops (Hypromellose, 3mg/ml)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A RCT Promoting Voluntary Medical Male Circumcision
Status: COMPLETED
Conditions: Behavior, Health
Interventions: BEHAVIORAL: Health education booklet plus video plus brief counseling|BEHAVIORAL: Health education booklet only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Digitalization of Osteoarthritis Care
Status: RECRUITING
Conditions: Osteoarthritis, Knee|Osteoarthritis, Hip
Interventions: OTHER: Patient information|OTHER: Smart phone application based exercises|OTHER: Web based exercises|OTHER: Group based information|OTHER: Supervised rehabilitation|OTHER: Self-monitoring|BEHAVIORAL: Motivational notifications|OTHER: Home based rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Physical Activity and Smell Trainings to Help Individuals With Coronavirus Disease (COVID-19) Recover From Persistent Smell and Taste Impairments - A Pilot Study
Status: UNKNOWN
Conditions: Covid19
Interventions: BEHAVIORAL: Physical activity|OTHER: Smell training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Motivational Interviewing on Treatment Adherence, Self-Efficacy, and Satisfaction in Individuals With Diabetic Foot Ulcers
Status: NOT_YET_RECRUITING
Conditions: Foot Ulcer, Diabetic
Interventions: BEHAVIORAL: Watson's human care theory-based motivational interviewing method
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Efficacy of Culturally Adapted iCT-SAD
Status: NOT_YET_RECRUITING
Conditions: Social Anxiety|ICT
Interventions: BEHAVIORAL: iCT-SAD-PK
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Clinical Study of Meplazumab to Treat With Malaria
Status: WITHDRAWN
Conditions: Malaria (Plasmodium Falciparum)
Interventions: DRUG: Meplazumab for Injection|DRUG: Sterile normal saline (0.9%)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Enhancing Exercise Training for Adults With COPD
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: BEHAVIORAL: Enhancing exercise training for adults with COPD: The roles of peers and functional tasks
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Manual Therapy and Use of the Dynasplint for Trismus in Patients With Head and Neck Cancer
Status: COMPLETED
Conditions: Neoplasms, Head and Neck|Trismus
Interventions: BEHAVIORAL: Physical therapy and dynasplint
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multi-center, Prospective, Single-blind, Controlled Trial Comparing Diagnostic Value of Different EUS-FNA Techniques
Status: UNKNOWN
Conditions: Neoplasms|Infection|Inflammation|Lymphoma|Cancer|Sarcoid|Mass Lesion
Interventions: PROCEDURE: Standard suction, slow-pull, wet suction|PROCEDURE: Standard suction, wet suction, slow-pull|PROCEDURE: Slow-pull, standard suction, wet suction|PROCEDURE: Slow-pull, wet suction, standard suction|PROCEDURE: Wet suction, standard suction, slow-pull|PROCEDURE: Wet suction, slow-pull, standard suction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Study to Evaluate the Efficacy and Safety of Camrelizumab and Apatinib in Patients With GC/GEJC
Status: UNKNOWN
Conditions: Gastric Cancer
Interventions: DRUG: camrelizumab|DRUG: Apatinib Mesylate|DRUG: Paclitaxel|DRUG: Irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Temsirolimus and Pemetrexed for Recurrent or Refractory Non-Small Cell Lung Cancer
Status: TERMINATED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: Pemetrexed|DRUG: Temsirolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Automatic Segmentation of Polycystic Liver
Status: UNKNOWN
Conditions: Polycystic Liver Disease|Polycystic Hepatorenal Disease|Liver Injury
Interventions: OTHER: Anonymized CT examinations|OTHER: Training (1)|OTHER: Training (2)|OTHER: Validation (1)|OTHER: Validation (2)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Digital Catheter Based Pancreatoscopy (SpyGlassDS) for the Management of Symptomatic Pancreatic Duct Stones in Selected Patients With Chronic Pancreatitis
Status: UNKNOWN
Conditions: Pancreatitis, Calcific|Pancreatitis, Chronic
Interventions: DEVICE: single operator video cholangioscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Therapist-Directed VS Online Therapy for Insomnia Co-Occuring With Sleep Apnea
Status: ACTIVE_NOT_RECRUITING
Conditions: Insomnia, Primary|Sleep Apnea, Obstructive
Interventions: BEHAVIORAL: Online Cognitive Behavioral Therapy (OCBT)|BEHAVIORAL: Therapist-directed Cognitive Behavioral Therapy (TCBT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Interleukin-12 in Treating Patients With Previously Treated Non-Hodgkin's Lymphoma or Hodgkin's Disease
Status: COMPLETED
Conditions: Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue|Nodal Marginal Zone B-cell Lymphoma|Recurrent Adult Diffuse Large Cell Lymphoma|Recurrent Adult Diffuse Mixed Cell Lymphoma|Recurrent Adult Diffuse Small Cleaved Cell Lymphoma|Recurrent Adult Hodgkin Lymphoma|Recurrent Adult Immunoblastic Large Cell Lymphoma|Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma|Recurrent Grade 1 Follicular Lymphoma|Recurrent Grade 2 Follicular Lymphoma|Recurrent Grade 3 Follicular Lymphoma|Recurrent Mantle Cell Lymphoma|Recurrent Marginal Zone Lymphoma|Recurrent Mycosis Fungoides/Sezary Syndrome|Recurrent Small Lymphocytic Lymphoma|Splenic Marginal Zone Lymphoma|Waldenström Macroglobulinemia
Interventions: BIOLOGICAL: recombinant interleukin-12|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized, Phase I/II, Dose-Ranging, Open-Label Trial of the Anti-HIV Activity of Delavirdine Mesylate (DLV; U-90,152S)
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Delavirdine mesylate|DRUG: Zidovudine|DRUG: Didanosine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Human Factors Validation Testing for the Peripal System; a Manual Connection Assist Device for Peritoneal Dialysis Devices
Status: COMPLETED
Conditions: End Stage Renal Failure on Dialysis|End Stage Renal Disease on Dialysis|Renal Failure|Peritoneal Dialysis|Renal Replacement Therapy
Interventions: DEVICE: Perisafe
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Stay Connected: Testing an Intervention to Combat Coronavirus-related Social Isolation Among Older Adults
Status: COMPLETED
Conditions: Depression|Anxiety|Loneliness
Interventions: BEHAVIORAL: Stay Connected|BEHAVIORAL: Treatment as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of NNC-0156-0000-0009 After Long-Term Exposure in Patients With Haemophilia B: An Extension to Trials NN7999-3747 and NN7999-3773
Status: COMPLETED
Conditions: Congenital Bleeding Disorder|Haemophilia B
Interventions: DRUG: nonacog beta pegol|DRUG: nonacog beta pegol|DRUG: nonacog beta pegol
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy of Amniotic Suspension Allograft in Patients With Osteoarthritis of the Knee
Status: RECRUITING
Conditions: Knee Osteoarthritis
Interventions: BIOLOGICAL: Amniotic Suspension Allograft|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Two Endometrium Preparation Protocols in Frozen-thawed Embryo Transfer in Women With Irregular Cycles
Status: UNKNOWN
Conditions: Infertility
Interventions: DRUG: Letrozole and human chorionic gonadotrophin|DRUG: estradiol and progesterone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Pharmacokinetics and Safety of Oral Decitabine and Cedazuridine in Cancer Patients With Hepatic Impairment
Status: RECRUITING
Conditions: Acute Myeloid Leukemia|Myelodysplastic Syndromes
Interventions: DRUG: ASTX727
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison FOLFIRINOX Panitumumab vs mFOLFOX6 Panitumumab in RAS/B-RAF Wild-type Metastatic Colorectal Cancer Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: Panitumumab, oxaliplatin, folinic acid, 5-fluoruracil|DRUG: Panitumumab, oxaliplatin, folinic acid, 5-fluoruracil, irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of the Safety and Efficacy of Anakinra (Recombinant Human Interleukin-1 Receptor Antagonist) in Pulmonary Hypertension
Status: TERMINATED
Conditions: Pulmonary Hypertension
Interventions: DRUG: Anakinra 100 mg subcutaneously daily
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: OptiCal COherence ToMography ABoard InformiNg AtherEctomy
Status: TERMINATED
Conditions: Atherectomy in Diseased Lower Extremity Arteries
Interventions: DEVICE: Wolverine System to perform atherectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Novel Parameters for the Prediction of Ventriculoperitoneal Shunting Efficacy in Patients With iNPH
Status: ACTIVE_NOT_RECRUITING
Conditions: Idiopathic Normal Pressure Hydrocephalus
Interventions: OTHER: Gait analysis and MRI:
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Clinical Study to Characterize Adverse Events Occurring Within One Day of TEGSEDI Administration to Adult Patients With hATTR-PN
Status: COMPLETED
Conditions: Hereditary Transthyretin Amyloidosis With Polyneuropthy
Interventions: PROCEDURE: Blood samples for immunoglobulins|PROCEDURE: Blood samples for inflammatory markers|PROCEDURE: Blood samples for anti-drug antibodies
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Aspirin in Preventing Colorectal Cancer in Patients at Increased Risk of Colorectal Cancer
Status: COMPLETED
Conditions: Colon Cancer|Precancerous Condition|Rectal Cancer
Interventions: DRUG: acetylsalicylic acid|DRUG: placebo|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Feasibility and Pilot Efficacy of Flash-heated Breast Milk to Reduce Maternal-to-Child-Transmission of HIV in Tanzania
Status: COMPLETED
Conditions: HIV Infections
Interventions: PROCEDURE: Infant feeding counseling that includes Flash-heat
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Icotinib for Completed Resected IB NSCLC With EGFR Mutation
Status: RECRUITING
Conditions: Lung Neoplasms|Squamous Cell Lung Cancer|Adenocarcinoma of the Lung|Adenosquamous Cell Lung Cancer|Large Cell Lung Cancer|Bronchial Neoplasms|Stage IB Non-small Cell Lung Cancer
Interventions: DRUG: Icotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preventive Approach Using Venlafaxine
Status: RECRUITING
Conditions: Peripheral Neuropathy Due to Chemotherapy
Interventions: DRUG: Venlafaxine 75 MG|DRUG: Gabapentin 400 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ANG1005 in Patients With Recurrent High-Grade Glioma
Status: COMPLETED
Conditions: Glioma|Glioblastoma|Brain Tumor, Recurrent
Interventions: DRUG: ANG1005|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Evaluate the Efficacy and the Safety of Monthly Versus Weekly Oral Risedronate With Vitamin D in Compliance, Improvement of Vitamin D and BMD in Korean Postmenopausal Osteoporotic Women
Status: COMPLETED
Conditions: Osteoporosis
Interventions: DRUG: Risedronate/Cholecalciferol combination(montly)|DRUG: Risedronate/Cholecalciferol combination(weekly)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Repeated Versus Varied Simulation Scenarios to Teach Medical Students the Management of a Pediatric Asthma Exacerbation
Status: COMPLETED
Conditions: Education, Medical
Interventions: OTHER: Variation of scenarios|OTHER: Repeated scenarios
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Evaluating a Telehealth Treatment for Veterans With Hepatitis C and PTSD
Status: COMPLETED
Conditions: Chronic Disease|Hepatitis C|Stress Disorders, Post-Traumatic
Interventions: BEHAVIORAL: Individual psychotherapy|BEHAVIORAL: Telehealth Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Office Bleaching Treatment by Using Rubber-cup and Air-powder Polishing Device Prophylaxis in Rondomised Clinical Design
Status: COMPLETED
Conditions: Tooth Discoloration|Color Changes During Tooth Formation
Interventions: COMBINATION_PRODUCT: AIRFLOW® Master device +Opalescence Xtra Boost.|COMBINATION_PRODUCT: rubber-cup+Opalescence Xtra Boost.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Self-applied Acupressure for Arthralgia-fatigue-sleep Disturbance in Breast Cancer
Status: TERMINATED
Conditions: Breast Neoplasms|Cancer Survivor
Interventions: OTHER: Ture self-acupressure|OTHER: Sham self-acupressure|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Impact of Alternative Nicotine-Delivery Products on Combustible Cigarette Use
Status: COMPLETED
Conditions: Nicotine Dependence
Interventions: DEVICE: Juul Electronic cigarette|OTHER: Very Low Nicotine Cigarettes|DRUG: Active Nicotine Patch|OTHER: Placebo Patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of ITI-007 in Healthy Geriatric Volunteers and in Geriatric Patients With Dementia
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: ITI-007|DRUG: Placebo|DRUG: ITI-007|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pediatric Chronic Kidney Disease Safety and Efficacy
Status: TERMINATED
Conditions: Chronic Kidney Disease|Hyperparathyroidism|Hyperparathyroidism, Secondary|Kidney Disease|Secondary Hyperparathyroidism
Interventions: DRUG: cinacalcet capsule|DRUG: placebo|DRUG: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Recovering Damaged Cells for Sequelae Caused by COVID-19, SARS-CoV-2
Status: UNKNOWN
Conditions: Sequelae of; Infection|Post Infection Glomerulonephritis|Post-Infectious Peripheral Neuralgia|Post-Infectious Disorder (Disorder)|Post-Infectious Arthritis|Post-Infectious Polyneuritis|Post-Infectious Parkinsonism|Post-Infectious Hypothyroidism|Post Infectious Osteoarthritis|Anxiety Disorders|Depression|Depression, Anxiety|Depression, Bipolar|Insomnia|GERD|Gastro Esophageal Reflux|Hepatitis|Glomerulonephritis
Interventions: COMBINATION_PRODUCT: PurWet|COMBINATION_PRODUCT: FurFat|COMBINATION_PRODUCT: PurApo|COMBINATION_PRODUCT: PurPhl|COMBINATION_PRODUCT: PurClo|COMBINATION_PRODUCT: PurInf|COMBINATION_PRODUCT: Smoliv
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Proactive Identification and Digital Mental Health Intervention Approach to Address Unmet Psychosocial Needs of Individuals Living With Cancer
Status: COMPLETED
Conditions: Depression|Depressive Symptoms|Cancer
Interventions: BEHAVIORAL: Behavioral Activation Therapy app|BEHAVIORAL: Treatment as Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dry Needling, Manipulation and Stretching vs. Manual Therapy, Exercise and Ultrasound for Lateral Epicondylalgia
Status: COMPLETED
Conditions: Lateral Epicondylitis
Interventions: OTHER: Dry Needling, manipulation, stretching|OTHER: manual therapy, exercise, ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: " Evaluation of Safety and Efficacy of Empagliflozin and Sacubitril/Valsartan for CHF With Reduced Ejection Fraction in ACHD "
Status: NOT_YET_RECRUITING
Conditions: Congenital Heart Disease|Heart Failure|Heart Failure With Reduced Ejection Fraction
Interventions: DRUG: Sacubitril 49 MG / Valsartan 51 MG [Entresto] BID|DRUG: Empagliflozin 10 MG OD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigation the Safety and Efficacy of The Antileukotriene Agents, Montelukast, as Adjuvant Therapy in Obese Patients With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Obesity; Endocrine; Diabetes Type 2
Interventions: DRUG: Montelukast 10mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of the Effect of BI 201335 on the QT Interval in Healthy Female and Male Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BI 201335 low dose|DRUG: BI 201335 placebo|DRUG: Moxifloxacin|DRUG: BI 201335 high dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Motexafin Gadolinium With MRI-Guided Surgery in Treating Patients With High-Grade Gliomas
Status: COMPLETED
Conditions: Brain and Central Nervous System Tumors
Interventions: DRUG: motexafin gadolinium|PROCEDURE: magnetic resonance imaging|PROCEDURE: surgical procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: DIAGNOSTIC
Clinical trial: Study to Investigate the Efficacy and Safety of FAB122 (Daily Oral Edaravone) in Patients With Amyotrophic Lateral Sclerosis
Status: ACTIVE_NOT_RECRUITING
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DRUG: FAB122|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Intralesional Cemiplimab in Adult Patients With Early Stage Cutaneous Squamous Cell Carcinoma
Status: NOT_YET_RECRUITING
Conditions: Cutaneous Squamous Cell Carcinoma (CSCC)
Interventions: DRUG: Cemiplimab|PROCEDURE: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Lenalidomide and Low-Dose Dexamethasone in Chinese Subjects With Relapsed/Refractory Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Lenalidomide|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 1b Safety Study of Xevinapant, Weekly Cisplatin, and RT in Participants With Unresected LA SCCHN (HyperlynX)
Status: ACTIVE_NOT_RECRUITING
Conditions: Head and Neck Cancer
Interventions: DRUG: Xevinapant|DRUG: Cisplatin|RADIATION: intensity-modulated radiation therapy (IMRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preventing Tipping Points in High Comorbidity Patients: A Lifeline From Health Coaches
Status: RECRUITING
Conditions: Comorbidity|Self-Management
Interventions: BEHAVIORAL: Health Coach Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A 12-Week Study in Participants With Refractory Chronic Cough (MK-7264-012)
Status: COMPLETED
Conditions: Refractory Chronic Cough
Interventions: DRUG: Gefapixant|DRUG: Placebo (for gefapixant)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Whole Body Prenatal Massage Therapy During Pregnancy: A Randomized Controlled Experimental Trial
Status: COMPLETED
Conditions: Massage Therapy|Pregnancy Related|Fetus Fetus
Interventions: OTHER: Prenatal massage therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Predicting Analgesic Response to Acupuncture: A Practical Approach
Status: COMPLETED
Conditions: Chronic Low Back Pain|Back Pain
Interventions: OTHER: Real Acupuncture with Electrical Stimulation|OTHER: Simulated Acupuncture with Electrical Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Robotic Rehabilitation and Brain Stimulation for Children With Hemiparetic Cerebral Palsy
Status: UNKNOWN
Conditions: Hemiplegic Cerebral Palsy|Perinatal Stroke
Interventions: COMBINATION_PRODUCT: Robot Rehabilitation + tDCS|BEHAVIORAL: Robotic Rehabilitation + sham tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT