pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Effects of Lidocaine Spray for Reducing Pain During Endometrial Aspiration Biopsy : a Randomized Controlled Trial
Status: COMPLETED
Conditions: Uterine Bleeding
Interventions: DRUG: Lidocaine spray|OTHER: Normal saline spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Midodrine and Albumine in the Prevention of Complications in Cirrhotic Patients Awaiting Liver Transplantation
Status: COMPLETED
Conditions: Renal Failure|Hyponatremia|Sepsis|Hepatic Encephalopathy|Gastrointestinal Bleeding
Interventions: DRUG: albumin|DRUG: Midodrine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Serum Prostatic Specific Antigen (PSA) After Cyproterone Compound Treatment Compared With Oral Contraceptives Pill in Hirsute Polycystic Ovary Syndrome Patients
Status: UNKNOWN
Conditions: Polycystic Ovary Syndrome
Interventions: DRUG: OCP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vascular Inflammation in Psoriasis Trial (The VIP Trial)
Status: COMPLETED
Conditions: Psoriasis|Cardiovascular Disease
Interventions: DRUG: Adalimumab (Humira)|DRUG: Placebo Injection|OTHER: NB-UVB phototherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the MiniMed™ 780G System in Type 1 Adult and Pediatric Subjects Utilizing Insulin Fiasp®
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: DEVICE: MiniMed 780G System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Long-Term Safety Study of Repeat Treatment With PurTox® for Frown Lines Between the Eyebrows
Status: COMPLETED
Conditions: Glabellar Rhytides
Interventions: DRUG: Mentor Purified Toxin Botulinum Toxin Type A
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Compare Ultrasound Assisted Cold Therapy and Lidocaine Injection to Treat Morton's Neuroma
Status: COMPLETED
Conditions: Intermetatarsal Neuroma
Interventions: DEVICE: Cryoablation|DRUG: Lidocaine|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Does Tranexamic Acid Decrease Blood Loss in Pediatric Idiopathic Scoliosis Surgery?
Status: COMPLETED
Conditions: Adolescent Idiopathic Scoliosis
Interventions: DRUG: Tranexamic Acid|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effectiveness of Reducing Smoking in Facilitating Smoking Cessation in Adolescents - 2
Status: COMPLETED
Conditions: Smoking Cessation|Tobacco Use Disorder
Interventions: DRUG: Usual Care|OTHER: Smoking Reduction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Carbon Filters to Reduce the Anesthetic Gas Concentration in an Anesthetized Patient
Status: WITHDRAWN
Conditions: Malignant Hyperthermia
Interventions: DEVICE: In-line Carbon filter (Vapor-Clean)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: LMB-2 Immunotoxin and Vaccine Therapy in Treating Patients With Metastatic Melanoma That Cannot Be Removed By Surgery
Status: COMPLETED
Conditions: Melanoma (Skin)|Non-melanomatous Skin Cancer
Interventions: BIOLOGICAL: LMB-2 immunotoxin|BIOLOGICAL: MART-1 antigen|BIOLOGICAL: gp100 antigen|BIOLOGICAL: incomplete Freund's adjuvant
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized Study of Whether Alfuzosin(Xatral) Helps in the Passage of Kidney Stones
Status: WITHDRAWN
Conditions: Kidney Stones
Interventions: DRUG: Alfuzosin (Xatral)|DRUG: Placebo Alfuzosin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Midodrine During Recovery From Septic Shock
Status: WITHDRAWN
Conditions: Hypotension|Shock, Septic|Sepsis
Interventions: DRUG: Midodrine|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Tarka vs. Hyzaar in Patients With Metabolic Syndrome (STAR)
Status: COMPLETED
Conditions: Hypertension|Metabolic Syndrome
Interventions: DRUG: trandolapril/verapamil|DRUG: (Hyzaar) losartan/hydrochlorothiazide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CNDO-109-AANK for AML in First Complete Remission (CR1)
Status: UNKNOWN
Conditions: Acute Myeloid Leukemia
Interventions: BIOLOGICAL: CNDO-109-AANK Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Adherence to Controller Inhalation Medication in Asthma- and COPD Patients.
Status: COMPLETED
Conditions: Asthma|COPD|Adherence, Medication
Interventions: OTHER: The 12-question TAI|OTHER: Information from patients file|OTHER: The Asthma Control Test (ACT)|OTHER: The COPD Assessment Test (CAT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effects of Resistive Diaphragmatic Training on Chronic Stroke
Status: COMPLETED
Conditions: Stroke (CVA) or TIA
Interventions: OTHER: Incentive spirometer training|OTHER: diaphragmatic resistance exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Tactile Stimulus, Music Play and Virtual Reality Video Watching During Non-Stress Test on Maternal Anxiety and Fetal Parameters
Status: COMPLETED
Conditions: Fetal Heart Failure|Fetal Movement Disorder
Interventions: OTHER: tactile stimulation group|OTHER: listen music|OTHER: virtual reality group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study in Patients Suffering From Idiopathic Restless Legs Syndrome Who Responded to a Preceding, 6-month Treatment With Open-label Pramipexole Including Titration (0.125, 0.25, 0.5, 0.75 mg Orally q.n.)
Status: COMPLETED
Conditions: Restless Legs Syndrome
Interventions: DRUG: Pramipexole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: CSI-Glucagon for Prevention of Hypoglycemia in Children With Congenital Hyperinsulinism
Status: COMPLETED
Conditions: Congenital Hyperinsulinism
Interventions: DRUG: Glucagon|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The APOS System: Effects on Gait, Mobility and QOL in Patients With Parkinson's Disease
Status: UNKNOWN
Conditions: Idiopathic Parkinson's Disease
Interventions: DEVICE: APOS System - biomechanical wedge shoe
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: FRESH Study (Fitness, Relaxation and Eating to Stay Healthy)
Status: COMPLETED
Conditions: Prediabetes|Overweight
Interventions: BEHAVIORAL: Stress Management|BEHAVIORAL: Diet|BEHAVIORAL: Exercise|BEHAVIORAL: Culinary education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Chemotherapy in Treating Patients With Cancer of Unknown Primary Origin
Status: UNKNOWN
Conditions: Carcinoma of Unknown Primary
Interventions: DRUG: carboplatin|DRUG: etoposide|DRUG: fluorouracil|DRUG: leucovorin calcium|DRUG: paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Impact of a Global Warming Strategy of the Patient on the Prevalence of Hypothermia in the Recovering Room
Status: NOT_YET_RECRUITING
Conditions: Hypothermia; Anesthesia|Perioperative/Postoperative Complications
Interventions: OTHER: global warming|OTHER: per operative warming
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Positive Psychotherapy Balance Model Based Psychoeducation for Caregivers of Oncology Patients
Status: NOT_YET_RECRUITING
Conditions: Cancer of Colon
Interventions: OTHER: Positive Psychotherapy Balance Model Based Psychoeducation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Filgrastim or Pegfilgrastim in Preventing Neutropenia in Women Receiving Chemotherapy Following Surgery for Breast Cancer
Status: UNKNOWN
Conditions: Breast Cancer|Neutropenia
Interventions: BIOLOGICAL: filgrastim|BIOLOGICAL: pegfilgrastim
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Neoadjuvant Docetaxel on Newly Diagnosed Intermediate and High Grade Cancer of the Prostate
Status: WITHDRAWN
Conditions: Prostate Cancer|Adenocarcinoma of the Prostate|Stage I Prostate Cancer|Stage II Prostate Cancer
Interventions: DRUG: Docetaxel|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low Flow Anesthesia in Morbid Obesity
Status: COMPLETED
Conditions: Morbid Obesity|Anesthesia Complication|Anesthesia; Functional
Interventions: PROCEDURE: Obesity Surgery with Low-Flow Anesthesia|PROCEDURE: Obesity Surgery with High-Flow Anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Development of Diagnostics and Treatment of Urological Cancers
Status: RECRUITING
Conditions: Prostate Carcinoma|Kidney Cancer|Urothelial Carcinoma|Testicular Cancer|Penile Cancer
Interventions: OTHER: Personalised treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tirbanibulin 1% Ointment for the Treatment of Actinic Keratosis on the Back of the Hands
Status: WITHDRAWN
Conditions: Actinic Keratoses
Interventions: DRUG: Tirbanibulin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Trial Comparing Morphine to Hydromorphone in Elderly Patients With Severe Pain
Status: COMPLETED
Conditions: Acute Pain
Interventions: DRUG: Morphine|DRUG: Hydromorphone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Immunity After Cochlear Implantation and Perilymph Molecular Profiles in Sensorineural Hearing Loss
Status: RECRUITING
Conditions: Sensorineural Hearing Loss
Interventions: BIOLOGICAL: Blood sampling|PROCEDURE: Perilymph sampling
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Adiposity and Airway Inflammation in HIV-Associated Airway Disease
Status: COMPLETED
Conditions: Asthma|HIV|Adiposity
Interventions: PROCEDURE: Blood draw|OTHER: Questionnaires|PROCEDURE: Spirometry|PROCEDURE: Methacholine challenge test|RADIATION: Quantitative CT scans|PROCEDURE: Urine pregnancy test|PROCEDURE: Adipose biopsy|PROCEDURE: Exhaled nitric oxide measurement
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Olfactory Training in Improving Sense of Smell After Radiation Therapy in Patients With Paranasal Sinus or Nasopharyngeal Cancer
Status: TERMINATED
Conditions: Stage 0 Nasopharyngeal Carcinoma|Stage 0 Paranasal Sinus Cancer|Stage I Nasopharyngeal Carcinoma|Stage I Paranasal Sinus Cancer|Stage II Nasopharyngeal Carcinoma|Stage II Paranasal Sinus Cancer|Stage IIA Nasopharyngeal Carcinoma|Stage IIB Nasopharyngeal Carcinoma|Stage III Nasopharyngeal Carcinoma|Stage III Paranasal Sinus Cancer|Stage IV Nasopharyngeal Carcinoma|Stage IV Paranasal Sinus Cancer|Stage IVA Nasopharyngeal Carcinoma|Stage IVA Paranasal Sinus Cancer|Stage IVB Nasopharyngeal Carcinoma|Stage IVB Paranasal Sinus Cancer|Stage IVC Nasopharyngeal Carcinoma|Stage IVC Paranasal Sinus Cancer
Interventions: OTHER: Physiologic Testing|OTHER: Quality-of-Life Assessment|PROCEDURE: Sham Intervention|PROCEDURE: Therapeutic Procedure|OTHER: rose essential oil|OTHER: lemon essential oil|OTHER: clove essential oil|OTHER: eucalyptus essential oil|OTHER: canola oil placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of PI3Kinase Inhibition (Copanlisib) and Anti-PD-1 Antibody Nivolumab in Relapsed/Refractory Solid Tumors With Expansions in Mismatch-repair Proficient (MSS) Colorectal Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Unresectable or Metastatic Microsatellite Stable (MSS) Solid Tumor Along With Microsatellite Stable (MSS) Colon Cancer|Colon Cancer
Interventions: DRUG: Copanlisib|DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: "Evaluation of Clinical and Radiographic Results of Pseudarthrosis of Clavicle Treated With Plaque and Screws"
Status: TERMINATED
Conditions: Pseudoarthrosis of the Clavicle
Interventions: PROCEDURE: pseudoarthrosis of clavicle
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Game-based HIIT Program on the Executive Function of Children With ADHD
Status: ACTIVE_NOT_RECRUITING
Conditions: Adhd Deficits in Attention Motor Control and Perception
Interventions: OTHER: Game-based High-Intensity Interval Training|OTHER: GameSAE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: NEPTUNE Match Study
Status: ENROLLING_BY_INVITATION
Conditions: Nephrotic Syndrome in Children|Focal Segmental Glomerulosclerosis|Minimal Change Disease|Minimal Change Nephrotic Syndrome|Membranous Nephropathy|FSGS|MCD|MCD - Minimal Change Disease
Interventions: OTHER: Communication
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy Trial of Ambisome Given Alone and Ambisome Given in Combination With Miltefosine for the Treatment of VL HIV Positive Ethiopian Patients.
Status: COMPLETED
Conditions: Visceral Leishmaniasis
Interventions: DRUG: Liposomal Amphotericin B|DRUG: Miltefosine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Investigate Alternative Dosing Regimens of Belantamab Mafodotin in Participants With Relapsed or Refractory Multiple Myeloma
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: Belantamab mafodotin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Family Therapy Training and Implementation Platform (FTTIP): An Innovative Web-based Tool for Long-term Practice Improvement
Status: RECRUITING
Conditions: Traditional Face to Face Training|Family Therapy Training and Implementation Platform (FTTIP)
Interventions: OTHER: Training on CIFFTA competencies using Family Therapy Training and Implementation Platform (FTTIP)|OTHER: Training on CIFFTA competencies using Training and Coaching as Usual (TCAU).|OTHER: Culturally Informed and Flexible Family-Based Treatment for Adolescents (CIFFTA).|OTHER: Agency Readiness Consultation- Family Therapy Training and Implementation Platform (FTTIP)|OTHER: Agency Engagement and Orientation as Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study of an Experimental Toothbrush for Treatment and Prevention of Gingivitis
Status: COMPLETED
Conditions: Dental Devices, Home Care
Interventions: DEVICE: Experimental Power Toothbrush|DEVICE: Flat trimmed Manual Toothbrush
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Esmolol on Pain Due to Rocuronium
Status: COMPLETED
Conditions: Injection Site Irritation
Interventions: DRUG: Lidocaine|DRUG: Esmolol|DRUG: rocuronium|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Energy Density and Portion Size of Milk in Preschool Children
Status: COMPLETED
Conditions: Feeding Behaviors
Interventions: BEHAVIORAL: Low energy density|BEHAVIORAL: High energy density|BEHAVIORAL: Small portion|BEHAVIORAL: Large portion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Validation of Different Diagnostic Modalities in the Detection of Cardiac Amyloidosis Among Patients With "Red Flags"
Status: NOT_YET_RECRUITING
Conditions: Cardiac Amyloidosis
Interventions: DIAGNOSTIC_TEST: CMR
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy & Long-term Safety Comparison Study of NK-104-CR & Livalo® IR With Primary Hyperlipidemia or Mixed Dyslipidemia
Status: WITHDRAWN
Conditions: Hyperlipidemia|Dyslipidemia
Interventions: DRUG: NK-104-CR|DRUG: Livalo® IR|DRUG: Placebo (for NK-104-CR)|DRUG: Placebo (for Livalo® IR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Namilumab for Moderate-to-severe Axial Spondyloarthritis
Status: COMPLETED
Conditions: Axial Spondyloarthritis
Interventions: BIOLOGICAL: Placebo|BIOLOGICAL: Namilumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Viral Oncoprotein Targeted Autologous T Cell Therapy for Merkel Cell Carcinoma
Status: TERMINATED
Conditions: Recurrent Merkel Cell Carcinoma|Stage IV Merkel Cell Carcinoma
Interventions: BIOLOGICAL: Aldesleukin|OTHER: Laboratory Biomarker Analysis|BIOLOGICAL: MCPyV TAg-specific Polyclonal Autologous CD8-positive T Cells|RADIATION: Radiation Therapy|BIOLOGICAL: Recombinant Interferon Beta
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ZD1839 and Oral Irinotecan in Treating Young Patients With Refractory Solid Tumors
Status: COMPLETED
Conditions: Glioblastoma|Rhabdomyosarcomas|Neuroblastoma|Osteosarcoma
Interventions: DRUG: Irinotecan (Camptosar), Gefitinib (Iressa)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Creating Peace: Community-based Youth Violence Prevention to Address Racism and Discrimination
Status: RECRUITING
Conditions: Adolescent Behavior|Group, Peer|Violence, Non-accidental|Violence, Sexual|Violence, Domestic|Emotional Abuse|Coping Skills|Communication, Personal
Interventions: BEHAVIORAL: Creating Peace|BEHAVIORAL: Job Readiness
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Coxsackie Virus A21 Administered Intravenously (IV) for Solid Tumour Cancers (PSX-X04)
Status: COMPLETED
Conditions: Melanoma|Breast Cancer|Prostate Cancer
Interventions: DRUG: CVA21
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intensified Tactile Contact With a Newborn Andt Emotional Transformation of the Mother
Status: COMPLETED
Conditions: Parturition|Depression, Postpartum
Interventions: OTHER: Shantali massage
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study Of Avelumab Alone Or In Combination With Pegylated Liposomal Doxorubicin Versus Pegylated Liposomal Doxorubicin Alone In Patients With Platinum Resistant/Refractory Ovarian Cancer (JAVELIN Ovarian 200)
Status: COMPLETED
Conditions: Ovarian Cancer
Interventions: BIOLOGICAL: avelumab|DRUG: PLD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cognitive Behavioural Therapy to Optimize Post-Operative Recovery Pilot
Status: TERMINATED
Conditions: Pain, Postoperative|Fractures, Open|Fractures, Closed
Interventions: BEHAVIORAL: Cognitive Behavioural Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Treatment for Moderate/Severe COVID-19 in a Fragile and Vulnerable Population, Admitted to a Geriatric Hospital Unit or in a Transicional Care Center
Status: TERMINATED
Conditions: Covid19
Interventions: DRUG: Colchicine|DRUG: Prednisone tablet|DRUG: standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study in Moderate to Severe Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Adalimumab|DRUG: Baricitinib|DRUG: Methotrexate|DRUG: Adalimumab Placebo|DRUG: Baricitinib Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dissector Assisted Malar Elevation for Rhytidoplasty
Status: UNKNOWN
Conditions: Aging|Premature Aging
Interventions: PROCEDURE: Dissector Assisted Malar Elevation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: GLP-1 Receptor Agonist Lixisenatide in Patients With Type 2 Diabetes for Glycemic Control and Safety Evaluation, on Top of Basal Insulin +/- Sulfonylurea (GETGOAL-L-ASIA)
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Lixisenatide (AVE0010)|DRUG: Placebo|DEVICE: Pen auto-injector|DRUG: Sulfonylurea|DRUG: Basal Insulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Reliability, Safety and Usability of the Transplantation Sensor System Combined With Myfortic® in Adult Kidney Transplant Patients
Status: COMPLETED
Conditions: Detection Accuracy|Patient Compliance
Interventions: DRUG: ECMPS-IEM
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Therapeutic Effects of R-IDARAM and Intrathecal Immunochemotherapy on Elderly Patients With PCNSL
Status: RECRUITING
Conditions: Primary Central Nervous System Lymphoma
Interventions: DRUG: R-IDARAM plus intrathecal chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Central and Peripheral Arterial Pressure Decoupling In Cardio-Pulmonary Bypass
Status: COMPLETED
Conditions: Cardiopulmonary Bypass|Cardiac Surgery|Extracorporeal Circulation
Interventions: PROCEDURE: Non-invasive blood pressure oscillometer (NIBP) implementation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Genetic Mutations in Blood and Tissue Samples in Predicting Response to Treatment in Patients With Locally Advanced Rectal Cancer Undergoing Chemoradiation
Status: COMPLETED
Conditions: Mucinous Adenocarcinoma of the Rectum|Recurrent Rectal Cancer|Signet Ring Adenocarcinoma of the Rectum|Stage IIA Rectal Cancer|Stage IIB Rectal Cancer|Stage IIC Rectal Cancer|Stage IIIA Rectal Cancer|Stage IIIB Rectal Cancer|Stage IIIC Rectal Cancer
Interventions: OTHER: cytology specimen collection procedure|OTHER: laboratory biomarker analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effectiveness of Bryophyllum in Nocturia-Therapy
Status: COMPLETED
Conditions: Nocturia|Sleep Disorder
Interventions: DRUG: Bryophyllum pinnatum 50 %, tablets into capsules (verum: 2x2capsules/day)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Progel® Pleural Air Leak Sealant (PALS) in Video and Robotic Assisted Thoracoscopic Surgery
Status: COMPLETED
Conditions: Pulmonary Disease
Interventions: DEVICE: Progel® Pleural Air Leak Sealant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phenytoin in the Healing of Clean Surgical Wounds
Status: UNKNOWN
Conditions: Wound|Re-Epithelialization
Interventions: DRUG: Phenytoin|DRUG: Sugar solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess Efficacy and Safety of Two Regimens of Crisaborole Ointment 2% in Japanese Participants Aged ≥2 Years With Mild to Moderate Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: Crisaborole ointment 2%|DRUG: Vehicle|DRUG: Crisaborole ointment 2%|DRUG: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Long-term Extension Study Evaluating a One-Month Dosing Regimen of Degarelix in Prostate Cancer Requiring Androgen Ablation Therapy
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: Degarelix 80 mg / Degarelix 80 mg|DRUG: Degarelix 160 mg / Degarelix 160 mg|DRUG: Leuprolide 7.5 mg / Degarelix 80 mg|DRUG: Leuprolide 7.5 mg / Degarelix 160 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Virtual Reality Glasses Application on Surgical Fear and Anxiety
Status: NOT_YET_RECRUITING
Conditions: Virtual Reality|Fear|Anxiety State|Surgery
Interventions: OTHER: virtual reality glasses application|OTHER: classical training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Limb Salvage Through Tissue Engineering: A Novel Treatment Modality Using Dehydrated Human Amnion/Chorion Membrane
Status: UNKNOWN
Conditions: Wounds|Trauma|Injury|Limb Salvage|Soft Tissue Injuries
Interventions: DEVICE: Dehydrated Human Amnion/Chorion Membrane|PROCEDURE: Flap-Based Reconstructive Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Modified AutoSet Device vs Existing AutoSet Device, the Assessment of Efficacy and Subjective Comfort of the Treatment.
Status: COMPLETED
Conditions: Sleep Apnea
Interventions: DEVICE: Nexus Flow Generator|DEVICE: VPAP Flow Generator 25
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety and Activity of SDX-105 (Bendamustine) in Patients With Rituximab Refractory Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Non-Hodgkin's Lymphoma
Interventions: DRUG: SDX-105
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Booster Study of Combined Diphtheria-tetanus-acellular Pertussis Vaccine in Healthy Adults
Status: COMPLETED
Conditions: Diphtheria|Pertussis|Tetanus
Interventions: BIOLOGICAL: GSK Biologicals' combined diphtheria, tetanus, acellular pertussis vaccine|BIOLOGICAL: GSK Biologicals' acellular pertussis vaccine|BIOLOGICAL: Commonwealth Serum Laboratories' combined diphtheria and tetanus vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Lutropin Alfa in Women at Risk of Poor Response
Status: COMPLETED
Conditions: Ovarian Stimulation
Interventions: DRUG: r-FSH|DRUG: r-hLH|DRUG: Analogous GnRH antagonist|DRUG: r-hCG|DRUG: Progesterone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Open Multiple Dose Titration Study In Patients With Pulmonary Hypertension
Status: COMPLETED
Conditions: Hypertension, Pulmonary
Interventions: DRUG: Riociguat (Adempas, BAY63-2521)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pragmatic Trial of Messaging to Providers About Treatment of Heart Failure
Status: COMPLETED
Conditions: Heart Failure With Reduced Ejection Fraction
Interventions: OTHER: Best practice alert for the notification of patient HFrEF and recommended evidence-based therapies (NO drugs are being administered in this trial)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Triple P With Pediatric Residents
Status: COMPLETED
Conditions: Psychosocial Problem|Problematic Behavior in Children|Parenting
Interventions: BEHAVIORAL: Training in PC Triple P|OTHER: Care As Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Radiation Therapy Using Holmium Ho 166 DOTMP Plus Melphalan and Peripheral Stem Cell Transplantation in Treating Patients With Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma and Plasma Cell Neoplasm
Interventions: DRUG: melphalan|PROCEDURE: peripheral blood stem cell transplantation|RADIATION: holmium Ho 166 DOTMP
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Hypothermia Prevention Measures in Osteosynthesis.
Status: COMPLETED
Conditions: Hypothermia|Hypothermia, Accidental|Hypothermia; Anesthesia
Interventions: OTHER: Hypothermia prevention bundle|OTHER: Conventional care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Prospective Randomized Controlled Trial for Prevention of Demineralization During Fixed Orthodontic Treatment
Status: UNKNOWN
Conditions: Demineralization, Tooth|Caries,Dental|White Spot Lesion
Interventions: DRUG: Fluoride Varnish|DRUG: Fluoride Varnish with tricalcium phosphate|OTHER: Oral health education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Time Restricted Eating for the Treatment of PCOS
Status: ENROLLING_BY_INVITATION
Conditions: Polycystic Ovary Syndrome|Obesity
Interventions: OTHER: 6-h Time restricted eating (TRE)|OTHER: Calorie restriction (CR)|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Histocompatibility Leukocyte Antigen (HLA)-A*2402 Restricted Peptide Vaccine Therapy in Patients With Non-Small Cell Lung Cancer
Status: UNKNOWN
Conditions: Non Small Cell Lung Cancer
Interventions: BIOLOGICAL: URLC10, TTK and KOC1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intensive Psychomotor Rehabilitation on Cognitive Motor Abilities and Adaptive Capacity on Children With Polyhandicap
Status: RECRUITING
Conditions: Polyhandicap
Interventions: BEHAVIORAL: Intentive rehabilitation|BEHAVIORAL: Routine care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Care Ecosystem: Navigating Patients and Families Through Stages of Care
Status: COMPLETED
Conditions: Dementia|Alzheimer Disease|Dementia, Vascular|Lewy Body Disease|Frontotemporal Lobar Degeneration|Memory Disorders
Interventions: BEHAVIORAL: Navigated Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phase II/III Trial of CPT-11/5-FU/l-LV Versus CPT-11/TS-1 as Second Line Chemotherapy of Unresectable Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: CPT-11 and TS-1|DRUG: CPT-11, 5-FU and l-LV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Levetiracetam Prophylaxis in Brain Tumor Resection Pilot
Status: NOT_YET_RECRUITING
Conditions: Seizures|Brain Tumor
Interventions: DRUG: Levetiracetam|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: GI Interlab 2 Study: Measuring the Glycaemic Index (GI) of Foods
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Test Meal: Reference food (glucose or white bread)|DRUG: Test Meal: Pirate's Booty|DRUG: Test Meal: Ceaprove wafer|DRUG: Test Meal: Stretch Island Strawberry Fruit Leather
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Modeling the Effects of Chronic Marijuana Use on Neuroinflammation and HIV-related Neuronal Injury
Status: RECRUITING
Conditions: Cannabis|HIV|Inflammation|Cognition|Neuroimaging
Interventions: OTHER: Multimodal, multi-parametric MRI|OTHER: Immune and cytokine profiling|BEHAVIORAL: Neuropsychological testing
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy of Expressive Writing on Quality of Life Among Breast Cancer Survivors in Oman: A Double Blind Randomized Controlled Trial
Status: NOT_YET_RECRUITING
Conditions: Breast Cancer|Quality of Life|Expressive Writing|Psychological
Interventions: BEHAVIORAL: Emotional Disclosure|BEHAVIORAL: Non-Emotional Writing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy of Lower Tourniquet Pressure During Total Knee Arthroplasty
Status: UNKNOWN
Conditions: Osteoarthritis
Interventions: PROCEDURE: Low tourniquet pressure|PROCEDURE: Conventional tourniquet pressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Glass Ionomer Cement Sealant in the Prevention of Post-eruptive Fractures in Molars Affected by MIH
Status: UNKNOWN
Conditions: Molar Incisor Hypomineralization
Interventions: PROCEDURE: GIC sealant (GC Fuji TRIAGE®)|PROCEDURE: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Amoxicillin for Enteral Nutrition Intolerance in Pediatric Intensive Care Unit
Status: RECRUITING
Conditions: Enteral Feeding Intolerance
Interventions: DRUG: Amoxicillin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study of TQB3454 Tablets in the Treatment of Advanced Biliary Carcinoma.
Status: NOT_YET_RECRUITING
Conditions: Biliary Carcinoma
Interventions: DRUG: TQB3454 tablets|DRUG: TQB3454 tablets matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Estimation of Vascularization After Treatment of Deep Rectovaginal Endometriosis Node by Rectal Shaving
Status: UNKNOWN
Conditions: Deep Endometriosis|Recto Vaginal Node
Interventions: DRUG: Indocyanine green
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigating the Neural Systems That Support the Beneficial Effects of Positive Emotion on Stress Regulation
Status: COMPLETED
Conditions: Behavior
Interventions: BEHAVIORAL: Positive Emotion Induction|BEHAVIORAL: Neutral Emotion Induction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Escitalopram Effects on CSF Amyloid Beta
Status: COMPLETED
Conditions: Amyloid Beta Protein
Interventions: DRUG: Escitalopram 20mg for 2 weeks|DRUG: Escitalopram 20mg for 8 weeks|DRUG: Escitalopram 30mg for 8 weeks|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Postprandial Effects of Bean and Whole Grain Consumption on Arterial Stiffness
Status: RECRUITING
Conditions: Arterial Stiffness
Interventions: DIETARY_SUPPLEMENT: black beans|DIETARY_SUPPLEMENT: wheat berries|DIETARY_SUPPLEMENT: white rice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Anti-VEGF Intravitreous Injections for Diabetic Macular Edema in Patients Undergoing Cataract Surgery
Status: UNKNOWN
Conditions: Diabetic Macular Edema|Cataract
Interventions: DRUG: Lucentis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Flaxseed Lignan-Enriched Complex (FLC) for the Treatment of Patients With Ulcerative Colitis (UC): A Pilot Assessment
Status: WITHDRAWN
Conditions: Ulcerative Colitis
Interventions: DIETARY_SUPPLEMENT: Flaxseed lignan-enriched complex (FLC)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Modified FOLFIRINOX for Gemcitabine Refractory Pancreatic Cancer: A Phase II Multicenter Trial
Status: COMPLETED
Conditions: Pancreatic Ductal Adenocarcinoma
Interventions: DRUG: modified FOLFIRINOX regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vascular Sealant Study
Status: TERMINATED
Conditions: Arteriovenous Access Grafts or Extra-anatomic and Infra-inguinal Grafts
Interventions: DEVICE: Vascular Sealant System|OTHER: Gelfoam/Thrombin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Novel Treatment of Comorbid Insomnia and Sleep Apnea in Older Veterans
Status: COMPLETED
Conditions: Insomnia|Apnea
Interventions: BEHAVIORAL: Insomnia treatment & PAP adherence|BEHAVIORAL: General sleep education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Perioperative Effect of Atenolol on Cytokine Profiles
Status: UNKNOWN
Conditions: Surgery
Interventions: DRUG: atenolol|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Local Intraoperative Analgesic Injection Versus Single Injection Interscalene Nerve Block in Patients Undergoing TSA
Status: COMPLETED
Conditions: Osteoarthritis: Shoulder
Interventions: PROCEDURE: Interscalene brachial plexus block|PROCEDURE: bupivacaine extended-release liposome injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cytogenetic Studies in Acute Leukemia and Multiple Myeloma
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Leukemia|Acute Lymphoblastic Leukemia|Myelodysplastic Syndrome|Multiple Myeloma
Interventions: GENETIC: cytogenetic analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: NEBIDO in Symptomatic Late Onset Hypogonadism (SLOH)
Status: TERMINATED
Conditions: Hypogonadism
Interventions: DRUG: Testosterone Undeconate (Nebido, BAY86-5037)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Empagliflozin as Adjunctive to InSulin thErapy Over 52 Weeks in Patients With Type 1 Diabetes Mellitus (EASE-2)
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: DRUG: Empagliflozin|DRUG: Empagliflozin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Immunization With 8 Peptides Mixed With CpG 7909 or Montanide ISA51 in Patients With Metastatic Cutaneous Melanoma
Status: TERMINATED
Conditions: Malignant Melanoma
Interventions: BIOLOGICAL: 8 HLA-A2-restricted peptides and Montanide ISA51|BIOLOGICAL: 8 HLA-A2-restricted peptides and CpG 7909
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Solidarity/Tokomeza Ebola Trial
Status: NOT_YET_RECRUITING
Conditions: Sudan Ebola Virus Vaccines
Interventions: BIOLOGICAL: CAd3|BIOLOGICAL: ChAdox1|BIOLOGICAL: rVSV-SUDV|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Influence of Omega-3 Fatty Acid on the Violence of Schizophrenia Patient and the Possible Mechanism
Status: UNKNOWN
Conditions: Schizophrenia
Interventions: BIOLOGICAL: omega-3 fatty acid|BIOLOGICAL: placebo|DEVICE: positron emission tomography (PET)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: EUS-guided Biliary Drainage of First Intent With the Lumen Apposing Metal Stent vs. ERCP in the Management of Malignant Distal Biliary Obstruction (AXIOS-CPRE)
Status: COMPLETED
Conditions: Endoscopic Retrograde Cholangiopancreatography|Biliary Drainage|Echography Ultrasound
Interventions: PROCEDURE: EUS guided biliary drainage|PROCEDURE: ERCP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Salonsip Compared to Sabiá Plaster
Status: UNKNOWN
Conditions: Contusions|Sprains|Myalgia|Pain|Tendonitis
Interventions: DRUG: Salonsip plaster|DRUG: Sabia plaster
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial of LY3056480 in Patients With SNLH
Status: WITHDRAWN
Conditions: Sensorineural Hearing Loss
Interventions: DRUG: LY3056480
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Drug-Drug Interaction (DDI) Study of Leramistat in Healthy Adult Subjects
Status: RECRUITING
Conditions: Pharmacokinetics
Interventions: DRUG: leramistat 40mg|DRUG: Itraconazole 200 mg|DRUG: Phenytoin 100 Mg Oral Capsule|DRUG: Simvastatin 40mg|DRUG: Upadacitinib 15 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Optimum Duration of Acoustic Pulse Thrombolysis Procedure in Acute Pulmonary Embolism
Status: COMPLETED
Conditions: Pulmonary Embolism and Thrombosis
Interventions: DEVICE: Ekosonic® Endovascular Device ultrasonic infusion catheter|BIOLOGICAL: Recombinant tissue plasminogen activator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasound-assisted Shamrock Method for Lumbar Plexus Nerve Block in Elderly Trauma Patients, Revisited.
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: PROCEDURE: lumbar plexus block
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ibuprofen Use on Post-operative Pain Following Cholecystectomy
Status: COMPLETED
Conditions: Acute Post-operative Pain
Interventions: DRUG: Ibuprofen 400 mg|DRUG: Acetaminophen 100 MG/ML
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT