pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Dose Escalation Study of E7107 Administered Intravenously on Days 1 and 8 Every 21 Days to Patients With Solid Tumors
Status: SUSPENDED
Conditions: Cancer
Interventions: DRUG: E7107
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: REWORD-HF REverse WOrsening Renal Function in Decompensated Heart Failure
Status: TERMINATED
Conditions: Acute Decompensated Heart Failure
Interventions: DRUG: Furosemide or Furosemide and Dopamine|DEVICE: Ultrafiltration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of the Ability of Subjects With Acromegaly or Their Partners to Administer Somatuline Autogel
Status: COMPLETED
Conditions: Acromegaly
Interventions: DRUG: Somatuline Autogel (lanreotide acetate)|BEHAVIORAL: Home administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects on Recovery of Children of Intravenous Formulation of Fentanyl Citrate and Midazolam Orally for Premedication
Status: ACTIVE_NOT_RECRUITING
Conditions: Separation Anxiety
Interventions: DRUG: Fentanyl Citrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: PAlbociclib Plus Tamoxifen for the Treatment of Hormone Receptor-positive, HER2-negative Advanced Breast Cancer Women - Asian studY
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Neoplasms
Interventions: DRUG: Palbociclib|DRUG: Placebo|DRUG: Tamoxifen|DRUG: Goserelin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Osteopathic Protocol for Insomnia in College Students
Status: NOT_YET_RECRUITING
Conditions: Insomnia
Interventions: OTHER: 4th ventricle compression technique|OTHER: Sham Technique|OTHER: Diaphragmatic breathing technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Efficacy and Safety of the Combined Oral Contraceptive (COC) NOMAC-E2 Compared to a COC Containing DRSP/EE (292001)(COMPLETED)(P05724)
Status: COMPLETED
Conditions: Contraception
Interventions: DRUG: NOMAC-E2|DRUG: DRSP-EE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Determining the Efficacy of Essential Oil Aromatherapy in Children Undergoing Port Access
Status: ENROLLING_BY_INVITATION
Conditions: Anxiety and Fear|Pain
Interventions: OTHER: STILL QuickTAB Medipack blended scent aromatherapy, manufactured by Soothing Scents
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study to Evaluate the Safety and Antiviral Activity of Remdesivir (GS-5734™) in Participants With Severe Coronavirus Disease (COVID-19)
Status: COMPLETED
Conditions: COVID-19
Interventions: DRUG: Remdesivir|DRUG: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cytokines Supplementation to Culture Media and ICSI Outcome
Status: COMPLETED
Conditions: ICSI
Interventions: COMBINATION_PRODUCT: A single step culture medium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Topiramate Trial for Pathological Gamblers
Status: COMPLETED
Conditions: Pathological Gambling
Interventions: DRUG: Topiramate flexible dosage|DRUG: Placebo matching tablets|BEHAVIORAL: 4-session gambling cognitive restructuring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase III Study of Lenalidomide and Dexamethasone With or Without Elotuzumab to Treat Newly Diagnosed, Previously Untreated Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Lenalidomide|DRUG: Dexamethasone|DRUG: Dexamethasone|DRUG: Dexamethasone|DRUG: Dexamethasone|BIOLOGICAL: Elotuzumab (BMS-901608; HuLuc63)|BIOLOGICAL: Elotuzumab (BMS-901608; HuLuc63)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Bone Growth in the Sacroiliac Joint After Minimally Invasive Surgery With Titanium Implants
Status: ACTIVE_NOT_RECRUITING
Conditions: Sacroiliac Dysfunction
Interventions: DEVICE: SIJ fusion with iFuse-3D
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Methylphenidate and a Nursing Telephone Intervention for Fatigue
Status: COMPLETED
Conditions: Advanced Cancer|Fatigue
Interventions: DRUG: Methylphenidate|BEHAVIORAL: Nursing Telephone Intervention|DRUG: Placebo|BEHAVIORAL: Non NTI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Surgical Sympathetic Blockade in Heart Failure
Status: COMPLETED
Conditions: Systolic Heart Failure|Beta-blockers Intolerance|Beta-blockers Resistance
Interventions: PROCEDURE: Left cervico-thoracic sympathetic blockade
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Temsirolimus and Vorinostat in Treating Patients With Metastatic Prostate Cancer
Status: TERMINATED
Conditions: Prostate Cancer|Adenocarcinoma of the Prostate|Hormone-resistant Prostate Cancer|Recurrent Prostate Cancer|Stage IV Prostate Cancer
Interventions: DRUG: vorinostat|DRUG: temsirolimus|OTHER: laboratory biomarker analysis|PROCEDURE: positron emission tomography/computed tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Erector Spinae Plane Block vs Local Infiltration Following Fusion Surgery
Status: RECRUITING
Conditions: Postoperative Delirium|Pain, Postoperative|Degenerative Disc Disease
Interventions: PROCEDURE: Erector Spinae Block|PROCEDURE: Local infiltration with local anesthetic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of Amlodipine Monotherapy or Combined With Terazosin on Lower Urinary Tract Symptoms and Hypertension
Status: COMPLETED
Conditions: Lower Urinary Tract Symptoms|Hypertension
Interventions: DRUG: amlodipine|DRUG: terazosin|DRUG: amlodipine plus terazosin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Lethal Means Counseling and an Active Control Condition, With and Without Provision of Gun Locks
Status: COMPLETED
Conditions: Intentional Self-Harm by Other Specified Means
Interventions: BEHAVIORAL: Lethal Means Counseling|BEHAVIORAL: Health and Stress Reduction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: MUSic Therapy In Complex Specialist Neurorehabilitation
Status: NOT_YET_RECRUITING
Conditions: Stroke|Subarachnoid Hemorrhage|Traumatic Brain Injury|Tumor, Brain|Autoimmune Diseases|Meningitis/Encephalitis|Acquired Brain Injury|Spinal Cord Injuries|Peripheral Nervous System Diseases
Interventions: BEHAVIORAL: Music Therapy|BEHAVIORAL: Control Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: TMC125-C216: A Phase III Study to Investigate the Efficacy, Tolerability and Safety of TMC125 as Part of an Antiretroviral Regimen, Including TMC114/Ritonavir and an Investigator-selected Optimized Background, in HIV-1 Infected Patients With Limited to no Treatment Options.
Status: COMPLETED
Conditions: HIV
Interventions: DRUG: TMC125|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Multi-center, Randomized, Double-blind, Phase II/III Clinical Trial of AK104 or Placebo in Combination With Chemotherapy as Second-line or More Lines for Recurrent or Metastatic Nasopharyngeal Carcinoma (NPC)
Status: RECRUITING
Conditions: Recurrent or Metastatic Nasopharyngeal Carcinoma
Interventions: DRUG: GP/PFLL+AK104|DRUG: GP/PFLL+placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Equivalent Effectiveness of 400 mcg Mometasone Furoate Using Two Different Dry Powder Inhalers in Moderate Asthmatics (Study P04828)
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Mometasone furoate dry powder inhaler|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison or Rose Bengal and Toluidine Blue Staining for Lesion Detection Efficacy
Status: COMPLETED
Conditions: Oral Leukoplakia|Oral Lichen Planus|Premalignant Lesion
Interventions: PROCEDURE: Biopsy|DIAGNOSTIC_TEST: Rose Bengal|DIAGNOSTIC_TEST: toluidine blue
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Increased Maternal Choline Intake on Child Cognitive Development
Status: RECRUITING
Conditions: Pregnancy
Interventions: DIETARY_SUPPLEMENT: 550 mg/day Choline|DIETARY_SUPPLEMENT: 25 mg/day Choline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tachikawa Project for Prevention of Posttraumatic Stress Disorder With Polyunsaturated Fatty Acid (TPOP): TPOP-02 Study
Status: COMPLETED
Conditions: Trauma|Posttraumatic Stress Disorder
Interventions: DIETARY_SUPPLEMENT: Omega-3 Polyunsaturated Fatty Acid|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Dual Implant Versus Single Implant Distal End of Femur
Status: RECRUITING
Conditions: Femur Fracture
Interventions: PROCEDURE: Single Distal Femur Implant|PROCEDURE: Dual Distal Femur Implant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Split-mouth Study of a New Flowable Composite in Non-carious Cervical Lesions
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-carious Cervical Lesions
Interventions: DEVICE: Restoration of non-carious cervical lesions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Potato Fiber and Gastrointestinal Function: Phase 3
Status: COMPLETED
Conditions: Gastrointestinal Symptoms|Gastrointestinal Transit Time|Stool Frequency
Interventions: DIETARY_SUPPLEMENT: PF-RS|DIETARY_SUPPLEMENT: PF-RO1|DIETARY_SUPPLEMENT: PF-RO2|DIETARY_SUPPLEMENT: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Brightline-1: A Study to Compare Brigimadlin (BI 907828) With Doxorubicin in People With a Type of Cancer Called Dedifferentiated Liposarcoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Liposarcoma, Dedifferentiated
Interventions: DRUG: Brigimadlin (BI 907828)|DRUG: Doxorubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Family Intervention for Chinese Americans With Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: BEHAVIORAL: Wait-list control group|BEHAVIORAL: SMS intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Dose-Ranging Study of SKF7® for Obesity
Status: COMPLETED
Conditions: Obesity
Interventions: OTHER: SKF7® Labisia pumila standardized extract
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Mesenchymal Stem Cells in Pre-term Patients With Bronchopulmonary Dysplasia.
Status: RECRUITING
Conditions: Bronchopulmonary Dysplasia
Interventions: BIOLOGICAL: Control|BIOLOGICAL: Allogenic fetal mesenchymal stem cells from umbilical cord - three infusions|BIOLOGICAL: Allogenic fetal mesenchymal stem cells from umbilical cord - six infusions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Impact of Grapefruit Juice on the Response to Clopidogrel
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Grapefruit juice|DRUG: Clopidogrel 75 mg/day|DRUG: Clopidogrel 300 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Comparison of Pegasys Versus Peg-Intron for Treatment of Chronic Hepatitis C Genotype 4
Status: COMPLETED
Conditions: Hepatitis C
Interventions: DRUG: Pegylated interferon alpha 2a|DRUG: Ribavirin|DRUG: Pegylated interferon alpha 2 b plus ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Increasing Serrated Polyp Detection With a Brief Awareness Training
Status: COMPLETED
Conditions: Serrated Polyp|Colorectal Neoplasms
Interventions: OTHER: Educational intervention (oral presentation)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Clinical Trial of PR001 (LY3884961) in Patients With Peripheral Manifestations of Gaucher Disease (PROCEED)
Status: RECRUITING
Conditions: Gaucher Disease|Gaucher Disease, Type 1
Interventions: GENETIC: LY3884961
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing of the Pharmacokinetics, Immunogenicity and Safety of MV088 and Prolia® in Healthy Adults.
Status: UNKNOWN
Conditions: Healthy
Interventions: DRUG: MV088 injection|DRUG: Prolia® injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study on the Treatment of Diabetic Kidney Disease With Shenxiao Yuning Decoction With Syndrome of Qi and Yin Deficiency and Blood Stasis
Status: ACTIVE_NOT_RECRUITING
Conditions: Diabetic Kidney Disease
Interventions: DRUG: Shenxiao Yuning decoction|DRUG: Symptomatic treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Rufinamide on Chronic Postthoracotomy Pain Syndrome
Status: WITHDRAWN
Conditions: Peripheral Nerve Injuries|Pain
Interventions: DRUG: Rufinamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Combination of Atezolizumab/Bevacizumab Versus Neoadjuvant Radiation Therapy
Status: RECRUITING
Conditions: Hepatocellular Carcinoma|Portal Vein Tumour Thrombosis
Interventions: COMBINATION_PRODUCT: Neoadjuvant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Electroacupuncture in Patients With Sepsis Associated Brain Injury
Status: UNKNOWN
Conditions: Electroacupuncture|Sepsis|Sepsis-associated Brain Injury
Interventions: OTHER: electroacupuncture|OTHER: shame electroacupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of R935788 Tablets to Treat Systemic Lupus Erythematosus
Status: WITHDRAWN
Conditions: Systemic Lupus Erythematosus
Interventions: DRUG: Fostamatinib Disodium (R935788)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomised Study to Compare the Effect of r-Hu-EPO Administration With Transfusion of Red Blood Cell Concentrates and Also With the Administration of Polyvitamins in Anemic and Tired Patients Presenting a Bad Prognostic in Middle Course
Status: TERMINATED
Conditions: - Medico-Economic Aspects (Evaluation of Medical Costs Related to the Three Strategies and Evaluation of Cost/Efficacy)
Interventions: DRUG: Erythropoiétine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety & Efficacy of Omeprazole Sodium Bicarbonate for the Prevention of Upper GI Bleeding in the Critically Ill
Status: COMPLETED
Conditions: Upper Gastrointestinal Bleeding
Interventions: DRUG: Omeprazole sodium bicarbonate immediate release PWD/FS|DRUG: Cimetidine IV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Tibial Nerve Stimulation in Combination With Biofeedback
Status: UNKNOWN
Conditions: Fecal Incontinence
Interventions: BEHAVIORAL: Biofeedback|DRUG: Loperamide|DRUG: Stool bulking agent (sterculia or ispaghula husk)|OTHER: PTNS
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Clinical Utility of Monitoring for Human Herpesvirus-6 (HHV-6) and Human Herpesvirus-7 (HHV-7) After Liver Transplant
Status: COMPLETED
Conditions: Transplant
Interventions: PROCEDURE: Monitoring - blood samples drawn to test for HHV-6 and HHV-7
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Dose-ranging Study to Evaluate the Efficacy, Safety, and Tolerability of AMG 133 in Adult Subjects With Overweight or Obesity, With or Without Type 2 Diabetes Mellitus
Status: ACTIVE_NOT_RECRUITING
Conditions: Obesity|Overweight|Type 2 Diabetes Mellitus
Interventions: BIOLOGICAL: Maridebart Cafraglutide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Swallowing Therapy With the Assistance of a Mobile Health Device in Head and Neck Cancer Patients: a Pan-Alberta Study
Status: COMPLETED
Conditions: Dysphagia|Head and Neck Cancer
Interventions: OTHER: Swallowing exercise from home
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility of Using Holographic Memory Resolution® (HMR) in Patients/Clients With Pain
Status: COMPLETED
Conditions: Chronic Pain|Headache, Migraine|Stress Disorders, Post-Traumatic
Interventions: BEHAVIORAL: Holographic Memory Resolution® (HMR)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Internal Thoracic Artery Skeletonization Study: A Paired, Within-Patient Comparison
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: PROCEDURE: Skeletonization of the internal thoracic artery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Genotype-guided Dosing of mFOLFIRINOX Chemotherapy in Patients With Previously Untreated Advanced Gastrointestinal Malignancies
Status: COMPLETED
Conditions: Acinar Cell Adenocarcinoma of the Pancreas|Adenocarcinoma of the Gallbladder|Adenocarcinoma of Unknown Primary|Adult Primary Cholangiocellular Carcinoma|Advanced Adult Primary Liver Cancer|Cholangiocarcinoma of the Extrahepatic Bile Duct|Cholangiocarcinoma of the Gallbladder|Diffuse Adenocarcinoma of the Stomach|Duct Cell Adenocarcinoma of the Pancreas|Intestinal Adenocarcinoma of the Stomach|Localized Unresectable Adult Primary Liver Cancer|Metastatic Carcinoma of Unknown Primary|Metastatic Extrahepatic Bile Duct Cancer|Mixed Adenocarcinoma of the Stomach|Mucinous Adenocarcinoma of the Colon|Mucinous Adenocarcinoma of the Rectum|Newly Diagnosed Carcinoma of Unknown Primary|Signet Ring Adenocarcinoma of the Colon|Signet Ring Adenocarcinoma of the Rectum|Stage III Pancreatic Cancer|Stage IIIA Colon Cancer|Stage IIIA Gallbladder Cancer|Stage IIIA Gastric Cancer|Stage IIIA Rectal Cancer|Stage IIIB Colon Cancer|Stage IIIB Gallbladder Cancer|Stage IIIB Gastric Cancer|Stage IIIB Rectal Cancer|Stage IIIC Colon Cancer|Stage IIIC Gastric Cancer|Stage IIIC Rectal Cancer|Stage IV Gastric Cancer|Stage IV Pancreatic Cancer|Stage IVA Colon Cancer|Stage IVA Gallbladder Cancer|Stage IVA Rectal Cancer|Stage IVB Colon Cancer|Stage IVB Gallbladder Cancer|Stage IVB Rectal Cancer|Unresectable Extrahepatic Bile Duct Cancer
Interventions: DRUG: oxaliplatin|DRUG: irinotecan hydrochloride|DRUG: leucovorin calcium|DRUG: fluorouracil|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Using Induction Chemotherapy and Intensity-Modulated Radiation Therapy Guided by Combined CT and PET Imaging for Patients With Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: PROCEDURE: Intensity-Modulated Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immediate Effects of Different Stretching Methods for Pectoralis Minor Muscle
Status: RECRUITING
Conditions: Rounded Shoulder Posture
Interventions: OTHER: Unilateral Corner Stretch|OTHER: Manual Stretching|OTHER: PNF Stretching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ultrasound-assisted or Landmark-based Intrathecal Administration of Nusinersen in Adult Patients With Spinal Muscular Atrophy (The EchoSpin Study)
Status: COMPLETED
Conditions: Anesthesia, Spinal|Spinal Puncture Complications|Spinal Muscular Atrophy|Ultrasonography
Interventions: PROCEDURE: Interlaminar ultrasound-assisted intrathecal administration of nusinersen|PROCEDURE: Landmark-based intrathecal administration of nusinersen
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Sensitivity of the Step Test to Detect Improvement in Dyspnea Following Bronchodilation in Patients With Chronic Obstructive Pulmonary Disease
Status: UNKNOWN
Conditions: Moderate Chronic Obstructive Pulmonary Disease|Severe Chronic Obstructive Pulmonary Disease|Dyspnea
Interventions: DRUG: Combination ipratropium/salbutamol or placebo (nebulization)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of Multiple Doses of Saxagliptin (BMS-477118)
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Saxagliptin|DRUG: Saxagliptin|DRUG: Saxagliptin|DRUG: Saxagliptin|DRUG: Saxagliptin|DRUG: Saxagliptin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigation of Surgical Sectioning of the Filum Terminale in Treating Occult Tethered Cord Syndrome Patients
Status: RECRUITING
Conditions: Tethered Cord|Tethered Cord Syndrome|Occult Spina Bifida|Spina Bifida Occulta
Interventions: PROCEDURE: Release of filum terminale
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CYP19A1 (Cytochrome P450 Family 19 Subfamily A Member 1) Gene and Pharmacogenetics of Response to Testosterone Therapy
Status: COMPLETED
Conditions: Hypogonadism
Interventions: DRUG: Testosterone Cypionate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Upfront Resection of Locally Advanced NSCLC Followed by Chemoradiotherapy
Status: NOT_YET_RECRUITING
Conditions: Locally Advanced Non-Small Cell Lung Cancer|Chemoradiotherapy|Cavitation Lung|Surgery|Feasibility|Safety
Interventions: PROCEDURE: Upfront resection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Danish Randomized Trial on Leadless vs Transvenous Pacing
Status: RECRUITING
Conditions: AV Block
Interventions: DEVICE: Leadless Micra AV Transcatheter Pacing System|DEVICE: Transvenous Azure XT DR dual chamber pacemaker
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transcutaneous Tibial Nerve Stimulation in Acute Spinal Cord Injury
Status: RECRUITING
Conditions: Spinal Cord Injury, Acute
Interventions: DEVICE: VERUM TTNS|DEVICE: SHAM TTNS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Tribulus Terrestris in Women With Hypoactive Sexual Desire Disorder
Status: COMPLETED
Conditions: Hypoactive Sexual Desire Disfunction
Interventions: DRUG: tribulus terrestris|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The SNORES Randomized Clinical Trial
Status: TERMINATED
Conditions: PCOS|Sleep Apnea
Interventions: OTHER: Screening for obstructive sleep apnea|DEVICE: CPAP - continuous positive airway pressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Improvement of Tolerance of Bowel Cleansing Before Colonoscopy in Diabetic Patients
Status: COMPLETED
Conditions: Diabetes Mellitus|Colonic Diseases
Interventions: DRUG: PEG-ascorbate 2L|DRUG: PEG 4L
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study Comparing the Pharmacokinetics of BK-C-0701 320mg, 480mg and Thiocacid HR Tab 600mg in Healthy Adult Male Subjects
Status: COMPLETED
Conditions: Healthy Adult Male
Interventions: DRUG: Thiocacid HR Tab 600mg|DRUG: BK-C-0701 320mg|DRUG: BK-C-0701 480mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial Evaluating the Efficacy and Safety of Favipiravir in Moderate to Severe COVID-19 Patients
Status: TERMINATED
Conditions: Covid19
Interventions: DRUG: AVIGAN|DRUG: Placebo Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Leucine Supplementation in Sarcopenic Older Individuals
Status: COMPLETED
Conditions: Frail Elderly Syndrome|Sarcopenia
Interventions: DIETARY_SUPPLEMENT: Leucine|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Treatment of Nimotuzumab With Chemotherapy or Radiotherapy in Resectable Esophageal Squamous Cell Carcinoma
Status: WITHDRAWN
Conditions: Esophageal Squamous Cell Carcinoma
Interventions: DRUG: Nimotuzumab|DRUG: Paclitaxel|DRUG: Cisplatin|RADIATION: Radiation|PROCEDURE: Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single-Dose Study of MT203
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: MT203 80 mg or matching Placebo|DRUG: MT203 150mg or matching Placebo|DRUG: MT203 300 mg or matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Time-restricted Eating to Improve Metabolic Abnormalities in Polycystic Ovarian Syndrome
Status: UNKNOWN
Conditions: PCOS|Hyperinsulinemia|Insulin Resistance
Interventions: OTHER: Time restricted eating|OTHER: Normal ad libitum diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Tamoxifen in Well Differentiated Neuroendocrine Tumors and Hormone Receptor Positive Expression
Status: COMPLETED
Conditions: Neuroendocrine Tumors|Progesterone Receptor Positive Tumor|Estrogen Receptor Positive Tumor
Interventions: DRUG: Tamoxifen
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Interventional Study Targeting Oral Infections in Patients With Chronic Kidney Disease
Status: COMPLETED
Conditions: Mouth Diseases|Renal Insufficiency, Chronic
Interventions: OTHER: Intensive oral care & didactic training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Predictive Factors for Ovarian Stimulation Using a Fixed Daily Dose of 200 IU Recombinant FSH (Study 142003)(P05696)
Status: COMPLETED
Conditions: Infertility
Interventions: DRUG: Marvelon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SAFIR02_Breast - Efficacy of Genome Analysis as a Therapeutic Decision Tool for Patients With Metastatic Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Breast Cancer
Interventions: DRUG: AZD2014|DRUG: AZD4547|DRUG: AZD5363|DRUG: AZD8931|DRUG: Selumetinib|DRUG: Vandetanib|DRUG: Bicalutamide|DRUG: Olaparib|DRUG: Anthracyclines|DRUG: Taxanes|DRUG: cyclophosphamide|DRUG: DNA intercalators|DRUG: Methotrexate|DRUG: vinca alkaloids|DRUG: Platinum based chemotherapies|DRUG: Bevacizumab|DRUG: Mitomycin C|DRUG: Eribulin|DRUG: MEDI4736
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: VTX958 Versus Placebo for the Treatment of Moderate to Severe Psoriasis
Status: TERMINATED
Conditions: Psoriasis
Interventions: DRUG: VTX958|DRUG: VTX958|DRUG: VTX958|DRUG: VTX958|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Delaying First Bathing and Skin Barrier Function on Infant
Status: COMPLETED
Conditions: Premature|Thermoregulation
Interventions: PROCEDURE: Bathing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Prospective, Controlled and Randomized Clinical Trial on Cardiac Cell Regeneration With Laser and Autologous Bone Marrow Stem Cells, in Patients With Coronary Disease and Refractory Angina
Status: UNKNOWN
Conditions: Angina|Coronary Disease
Interventions: PROCEDURE: Transmyocardial revascularization (TMR) with Holmium YAG laser|PROCEDURE: Transmyocardial revascularization (TMR) with Holmium YAG laser plus the patient's own stem cells extracted from bone marrow.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Social Risk Score, Clinical Decision Support Tool and Closed Loop Referral for Social Risk Screen and Referral
Status: RECRUITING
Conditions: Chronic Disease|Diabetes Mellitus|Hypertension|Congestive Heart Failure
Interventions: OTHER: Social Risk Score and CDS Tool|OTHER: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Assessment of the Effects of Early Proprioceptive Stimulations in Patients With Severe Traumatic Brain Injury
Status: RECRUITING
Conditions: Traumatic Brain Injuries
Interventions: DEVICE: Proprioceptive stimulations|DEVICE: Sham stimulations
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Stem Cell Transplantation for Patients With Graft Failure Following an Allogeneic Transplant, Using Identical or Near Identical Donors and Less Toxic Conditioning With CAMPATH 1H
Status: TERMINATED
Conditions: Graft Failure
Interventions: DRUG: Fludarabine|DRUG: CAMPATH 1H|DRUG: FK506|PROCEDURE: Stem Cell Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Follow-Up Evaluation for Gene-Therapy-Related Delayed Adverse Events After Participation in Pediatric Oncology Branch Clinical Trials
Status: ENROLLING_BY_INVITATION
Conditions: Pediatric Cancers|Hematologic Malignancies|Solid Tumors
Interventions: DRUG: anti-CD19 CAR
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy, Safety, Tolerability of Neramexane in Patients With Subjective Tinnitus
Status: COMPLETED
Conditions: Subjective Tinnitus
Interventions: DRUG: Neramexane mesylate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of ASA on Prostate Tissue
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: Aspirin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Pectin and Inulin Fibre Supplementation on Glucose and ANS Modulation
Status: ACTIVE_NOT_RECRUITING
Conditions: Diet, Healthy|Systemic Inflammatory Response
Interventions: DIETARY_SUPPLEMENT: Fibre intervention|DIETARY_SUPPLEMENT: Placebo intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Taste Acceptability of Tomato-Soy-Arugula Seed Beverages in Men With Prostate Cancer
Status: COMPLETED
Conditions: Prostate Carcinoma
Interventions: OTHER: Survey Administration|DIETARY_SUPPLEMENT: Tomato-Soy Juice
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Neoadjuvant Study With Chemotherapy, Lapatinib And Trastuzumab In Breast Cancer
Status: COMPLETED
Conditions: Neoplasms, Breast
Interventions: DRUG: lapatinib|BIOLOGICAL: trastuzumab|DRUG: paclitaxel|DRUG: fluorouracil|DRUG: epidoxorubicin|DRUG: cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A New Nutritional Countermeasure to Prevent the Deconditioning Induced by 60 Days of Antiorthostatic Bed Rest
Status: COMPLETED
Conditions: Weightlessness|Weightlessness; Adverse Effect
Interventions: OTHER: Bed Rest Control Group|DIETARY_SUPPLEMENT: Cocktail intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Posterior Spinal Fusion With Two Energy Dissection Techniques
Status: TERMINATED
Conditions: Scoliosis
Interventions: DEVICE: Ultrasonic Dissection (UD)|DEVICE: Electrocautery Dissection (ED)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of I-124 and I-131 Radiopharmacokinetics in DTC Patients With Thyroid Hormone Withdrawal
Status: TERMINATED
Conditions: Thyroid Cancer
Interventions: RADIATION: Radioactive Iodine 124
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Lifestyle Change for Better Health
Status: ACTIVE_NOT_RECRUITING
Conditions: Bladder Cancer|Telomere Shortening|Colorectal Adenoma
Interventions: BEHAVIORAL: Dietary Intervention|BEHAVIORAL: Physical Activity Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of the Immunomodulation in the Hidradenitis Suppurativa and Evaluation of a New Therapeutic Strategy
Status: NOT_YET_RECRUITING
Conditions: Hidradenitis Suppurativa
Interventions: BIOLOGICAL: Blood tests|PROCEDURE: exeresis|PROCEDURE: abdominoplasty
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of the Consumption of a Combination of Plant Extracts (BSL_EP026) on Serum Uric Acid.
Status: COMPLETED
Conditions: Hyperuricemia
Interventions: COMBINATION_PRODUCT: Combination of Plant Extracts (BSL_EP026)|COMBINATION_PRODUCT: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Premotor Cortex: A New Target for Stroke Motor Rehabilitation
Status: SUSPENDED
Conditions: Stroke
Interventions: DEVICE: rTMS over Premotor Cortex (Contralateral Hemisphere)|DEVICE: rTMS over Premotor Cortex (Ipsilateral Hemisphere)|DEVICE: rTMS (Control 1)|DEVICE: rTMS (Control 2)|DEVICE: rTMS (Control 3)|OTHER: Motor Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Par-4 and Telomere-telomerase System in Type 2 Diabetes Patients Who Received GLP-1 or Metformin Treatment
Status: UNKNOWN
Conditions: GLP-1；Metformin；Telomere-telomerase System；Par-4
Interventions: DRUG: Liraglutide|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Effectiveness of Iron Hydroxide Adipate Tartrate (IHAT) in Iron Deficient Premenopausal Women
Status: RECRUITING
Conditions: Iron-deficiency
Interventions: DRUG: Low Dose IHAT|DRUG: High Dose IHAT|DRUG: Carob Flour
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Recombinant Human Coagulation Factor VIIa for Injection (FⅦa) in Patients With Hemophilia.
Status: UNKNOWN
Conditions: Hemophilia A With Inhibitor|Hemophilia B With Inhibitor
Interventions: DRUG: TQG203|DRUG: TQG203/NovoSeven®|DRUG: TQG203
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Boosted Lexiva With Lovaza Adjunctive Therapy in Hypertriglyceridemic, HIV-Infected Subjects
Status: COMPLETED
Conditions: Hypertriglyceridemia|HIV Infection
Interventions: DIETARY_SUPPLEMENT: Lovaza|DRUG: fosamprenavir/ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of the Low-level Laser Therapy on Inflammatory Profile of the Patients With Coronary Artery Bypass Surgery
Status: UNKNOWN
Conditions: Cardiovascular Diseases
Interventions: DEVICE: 0J LLLT|DEVICE: 6J LLLT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of a Nutritional Supplementation on the Functional Status of Frail Elders With Low Socioeconomic Status (SES)
Status: COMPLETED
Conditions: Frail
Interventions: DIETARY_SUPPLEMENT: Nutritional Supplementation|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Efficacy and Safety of Narrow Focus (F1) Versus Wide Focus (F3) of Shock Wave Lithotripsy (SWL) for Renal Calculi
Status: RECRUITING
Conditions: Renal Stone|Treatment Side Effects
Interventions: PROCEDURE: Shock Wave Lithotripsy (SWL)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Use of a Novel Peer Education Program for Improving PTSD Treatment Engagement Among Veterans
Status: COMPLETED
Conditions: PTSD|Posttraumatic Stress Disorder
Interventions: BEHAVIORAL: AboutFace|OTHER: Enhanced Usual Care (eUC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Nivolumab With Standard of Care Chemotherapy for Peripheral T Cell Lymphomas
Status: ACTIVE_NOT_RECRUITING
Conditions: Peripheral T Cell Lymphoma
Interventions: DRUG: Nivolumab|DRUG: Etoposide|DRUG: Prednisolone|DRUG: Oncovin|DRUG: Cyclophosphamide|DRUG: Hydroxydaunorubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tobacco Retraining of Automatic Approach to Treat Individuals With Tobacco Dependence and Severe Concurrent Disorders.
Status: WITHDRAWN
Conditions: Tobacco Retraining of Automatic Approach|Placebo Task
Interventions: BEHAVIORAL: TRAA intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Feasibility and Safety of Early Switch to Everolimus From Cyclosporine in de Novo Renal Transplant Patients
Status: COMPLETED
Conditions: De Novo Renal Transplantation
Interventions: DRUG: everolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A First-in-man Phase I/II Study of Oral ONC201 in Patients With Advanced Cancer
Status: WITHDRAWN
Conditions: Advanced Glioblastoma|Advanced Colorectal Cancer|Advanced Triple-negative Breast Cancer|Advanced Non-small Cell Lung Cancer
Interventions: DRUG: ONC201
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improving the Quality of Life of Cancer Patients Through a Perioperative and Coordinated Nutrition and Physical Care Program.
Status: UNKNOWN
Conditions: Undernourished|Digestive Cancer
Interventions: OTHER: Dietary advice|OTHER: Physiotherapist intervention|OTHER: Dietary intervention|OTHER: Intensify physiotherapist intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Prasugrel Versus Clopidogrel to TREAT High Platelet Reactivity
Status: COMPLETED
Conditions: Acute Coronary Syndrome
Interventions: DRUG: Clopidogrel reloading|DRUG: Prasugrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cost Effectiveness of Outpatient Set-up of Automated NIV in Obese Patients With Chronic Respiratory Failure
Status: COMPLETED
Conditions: Obesity Hypoventilation Syndrome|Chronic Respiratory Failure
Interventions: DEVICE: Outpatient NIV Set Up using AVAPS AE (Manufactured by Philips-Respironics)|DEVICE: Inpatient NIV Set Up using spontaneous/timed (S/T) mode pressure support ventilation (Manufactured by Philips-Respironics)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Transfusion Therapy Using Whole Blood in the Management of Coagulopathy in Patients With Acute Traumatic Hemorrhage
Status: RECRUITING
Conditions: Trauma|Acute Hemorrhage|Coagulopathy
Interventions: DRUG: Whole blood transfusion|DRUG: Fractionated blood products transfusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: AMH and Dosing Regimens for Initial IVF Stimulation Protocols
Status: COMPLETED
Conditions: Infertility
Interventions: DRUG: 300IU Gonal-F|DRUG: 150IU Menopur|DRUG: 225IU Gonal-F|DRUG: 75IU Menopur|DRUG: 150IU Gonal-F|DRUG: 75IU Gonal-F
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Dexmedetomidine and Propofol on the Delirium and Neuroinflammation in Patients With SIRS.
Status: WITHDRAWN
Conditions: Delirium
Interventions: DRUG: Dexmedetomidine|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT