pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Brain Mechanisms Underlying Reading Improvement in Central Alexia
Status: COMPLETED
Conditions: Stroke|Brain Injuries|Aphasia
Interventions: BEHAVIORAL: Computer-based behavioural word reading therapy|OTHER: Real tDCS|OTHER: Sham tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Mindful Self-Compassion for Anxiety Disorders and Depression
Status: RECRUITING
Conditions: Anxiety Disorders|Generalized Anxiety Disorder|Social Anxiety Disorder|Social Phobia|Panic Disorder|Agoraphobia|Major Depressive Disorder
Interventions: BEHAVIORAL: Mindful Self-Compassion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Multicenter Study to Perioperative Chemotherapy for Resectable Adenocarcinoma in Gastric Cancer
Status: UNKNOWN
Conditions: Gastric Cancer
Interventions: DRUG: Docetaxel 50 mg/m2, 1-hour-Infusion, day 1|DRUG: Oxaliplatin 85 mg/m², 2-hour-Infusion, day 1|DRUG: Folinic acid 200 mg/m², 1-2-hour-Infusion, day 1|DRUG: 5-FU 2600 mg/m², 24-hour-Infusion, day 1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: House Dust Mite Allergy Trial In Children
Status: COMPLETED
Conditions: Allergic Rhinitis Due to Dermatophagoides Farinae|Allergic Rhinitis Due to Dermatophagoides Pteronyssinus|Allergic Rhinitis Due to House Dust Mite
Interventions: BIOLOGICAL: Sublingual allergy immunotherapy tablet|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Atorvastatin on the Frequency of Ventilator-associated Pneumonia in Patients With Ischemic Stroke
Status: UNKNOWN
Conditions: Ventilator-associated Pneumonia|Ischemic Stroke
Interventions: DRUG: Atorvastatin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: MRI-Guided Lattice Extreme Ablative Dose Radiotherapy For Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer|Prostate Adenocarcinoma
Interventions: RADIATION: Lattice Extreme Ablative Dose Radiation Therapy|RADIATION: Standard IMRT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity Study of Three Candidate HIV-1 Vaccines, Administered in Combination to Healthy HIV-1 Uninfected Adults
Status: COMPLETED
Conditions: HIV-1 Infections
Interventions: BIOLOGICAL: ChAdV63.HIVconsv low dose.|BIOLOGICAL: ChAdV63.HIVconsv high dose.|BIOLOGICAL: pSG2.HIVconsv|BIOLOGICAL: MVA.HIVconsv|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Alveolar Management Following Teeth Extraction
Status: TERMINATED
Conditions: Alveolar Bone Loss|Bone Resorption
Interventions: DRUG: Human-Spongiosa|DEVICE: collacone®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Effectiveness and Safety of Transcranial Magnetic Stimulation (rTMS) Combined With Transcranial Direct Current Stimulation (tDCS) in Dementia Treatment in Alzheimer's Disease
Status: UNKNOWN
Conditions: Alzheimer Disease
Interventions: DEVICE: Magnetic Stimulator DuoMag|DEVICE: neuroConn DC-STIMULATOR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating Amplex Compared To Autograft Bone In Foot and Ankle Fusion Surgery
Status: UNKNOWN
Conditions: Arthritis
Interventions: DEVICE: Amplex|PROCEDURE: Autograft bone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Repeated Intranasal Esketamine Plus Almond Therapy in Patients With Treatment Resistant Depression
Status: TERMINATED
Conditions: Treatment Resistant Major Depressive Disorder
Interventions: BEHAVIORAL: Psychotherapy|BEHAVIORAL: Treatment as Usual|DRUG: Intranasal Ketamine (esketamine)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating Anodal tDCS Preceding Aphasia Therapy
Status: TERMINATED
Conditions: Stroke|Aphasia
Interventions: DEVICE: transcranial direct current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II Study of Ofatumumab Plus Ifosfamide, Carboplatin, Etoposide (ICE) or Dexamethasone, Cytarabine, Cisplatin (DHAP) Chemotherapy Regimen in Relapsed/ Refractory Diffuse Large B Cell Lymphoma (DLBCL)
Status: COMPLETED
Conditions: Lymphoma, Large-Cell, Diffuse
Interventions: DRUG: ofatumumab + ICE|DRUG: ofatumumab + DHAP
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endoscopic vs. Suction Device Calibration in Sleeve Gastrectomy
Status: COMPLETED
Conditions: Gastrectomy|Obesity
Interventions: DEVICE: ViSiGi® 3D suction calibration device|DEVICE: Esophagogastroduodenoscopy (EGD) calibration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 2-HOBA: Multiple Dosing Study in Older Adults
Status: COMPLETED
Conditions: Older Adults
Interventions: DIETARY_SUPPLEMENT: 2-HOBA|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Myeloablative Conditioning Regimen and Total Body Irradiation Followed by the Transplantation for Patients With Hematological Malignancy
Status: COMPLETED
Conditions: Cancer|Leukemia|Myelodysplastic Syndrome|Non-Hodgkin's Lymphoma
Interventions: DRUG: Fludarabine, Cyclophosphamide|PROCEDURE: Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ZOSTAVAX™ in Patients on Chronic/Maintenance Corticosteroids (V211-017) (COMPLETED)
Status: COMPLETED
Conditions: Herpes Zoster
Interventions: BIOLOGICAL: Zoster Vaccine, Live|BIOLOGICAL: Comparator: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Eltrombopag Plus Lenalidomide Combination Therapy in Patients With IPSS Low and Intermediate-risk Myelodysplastic Syndrome With Isolated del5q
Status: TERMINATED
Conditions: Myelodysplastic Syndromes
Interventions: DRUG: Eltrombopag/Revolade|OTHER: Placebo|DRUG: Lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Dara-CyBorD in Previously Untreated and Relapsed Subjects With Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Daratumumab|DRUG: Cyclophosphamide|DRUG: Bortezomib|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Advancing Renal TRANSplant eFficacy and Safety Outcomes With an eveRolimus-based regiMen (TRANSFORM)
Status: COMPLETED
Conditions: End Stage Renal Disease (ESRD)|Chronic Kidney Disease (CKD)|Hemodialysis|Renal Replacement Therapy|Renal Transplantation
Interventions: BIOLOGICAL: Induction therapy|DRUG: Corticosteroids|DRUG: EVR+rCNI|DRUG: MPA+sCNI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Fluid Management Within a Goal-directed Hemodynamic Protocol on Acid-base Balance in Elective Trauma Surgery
Status: COMPLETED
Conditions: Hemodynamic Instability
Interventions: DRUG: Infusion Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, and Pharmacokinetics After Multiple Doses of Orally Inhaled DNAzyme Solution for Nebulisation in Healthy Male Subjects
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: SB010|DRUG: Placebo (phosphate-buffered saline)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Micropulse Laser Trabeculoplasty (532nm) Versus Conventional Laser Trabeculoplasty (532nm)
Status: COMPLETED
Conditions: Open Angle Glaucoma
Interventions: PROCEDURE: lasertrabeculoplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bioavailability of Technosphere® Insulin Versus Subcutaneous Regular Human Insulin in Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Technosphere Insulin|DRUG: Actrapid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Prostatic Artery Embolization (PAE) in Patients With Severe Benign Prostatic Hyperplasia (BPH)
Status: COMPLETED
Conditions: Benign Prostatic Hyperplasia
Interventions: DEVICE: Microspheres
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: SUPPORT-D Intervention for Persons With Alzheimer's Disease and Their Caregivers
Status: COMPLETED
Conditions: Alzheimer Disease|Mild Cognitive Impairment
Interventions: BEHAVIORAL: A Program of SUPPORT-D (dementia)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Treatment of Adults With Growth Hormone Deficiency
Status: COMPLETED
Conditions: Pituitary Disorders|Adult Growth Hormone Deficiency
Interventions: DRUG: growth hormone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Protocolized Initiation of Clonidine to Prevent Dexmedetomidine Withdrawal
Status: COMPLETED
Conditions: Withdrawal; Therapeutic Substance
Interventions: DRUG: Clonidine (without protocolized initiation)|DRUG: Clonidine (protocolized initiation)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Obinutuzumab and Lenalidomide in Treating Patients With Previously Untreated Stage II-IV Grade 1-3a Follicular Lymphoma
Status: COMPLETED
Conditions: Ann Arbor Stage II Grade 1 Follicular Lymphoma|Ann Arbor Stage II Grade 2 Follicular Lymphoma|Ann Arbor Stage III Grade 1 Follicular Lymphoma|Ann Arbor Stage III Grade 2 Follicular Lymphoma|Ann Arbor Stage IV Grade 1 Follicular Lymphoma|Ann Arbor Stage IV Grade 2 Follicular Lymphoma|Bulky Disease|Fatigue|Fever|Grade 3a Follicular Lymphoma|Night Sweats|Splenomegaly|Weight Loss
Interventions: DRUG: Lenalidomide|BIOLOGICAL: Obinutuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antidepressant Plus Asenapine Versus Antidepressant Plus Placebo for Depression
Status: COMPLETED
Conditions: Major Depressive Disorder Without Psychotic Features
Interventions: DRUG: Asenapine 5-20 mg daily|DRUG: Placebo 1-4 tablets daily
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Pharmacokinetics of Sialic Acid Tables in Patients With Hereditary Inclusion Body Myopathy (HIBM)
Status: COMPLETED
Conditions: Hereditary Inclusion Body Myopathy (HIBM)
Interventions: DRUG: Sialic Acid Extended Release (SA-ER) Tablets|DRUG: Sialic Acid Extended Release (SA-ER) Tables|DRUG: Sialic Acid Extended Release (SA-ER) Tablets|DRUG: Sialic Acid Extended Release (SA-ER) Tablets|DRUG: Sialic Acid Extended Release (SA-ER) Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Disitamab Vedotin Plus Trastuzumab in Patients With HER2 Positive GC/GEJ Patiens
Status: RECRUITING
Conditions: HER2-positive Gastric Cancer|HER2-positive Gastroesophageal Junction Adenocarcinoma
Interventions: DRUG: Disitamab Vedotin(RC48) Plus Tratuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of YH14618 in Patients With Degenerative Disc Disease
Status: COMPLETED
Conditions: Disc Degenerative Disease
Interventions: DRUG: Placebo|DRUG: YH14618
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pitavastatin on Carotid Intima-media Thickness
Status: UNKNOWN
Conditions: Hyperlipidemia|Carotid Artery Diseases
Interventions: DRUG: Pitavastatin|DRUG: Pitavastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CORTERAS STUDY: The Effect of Corticosteroids on Early Recovery After Major Surgery in Elderly Patients
Status: RECRUITING
Conditions: Inflammatory Response|Weakness, Muscle
Interventions: DRUG: Methylprednisolone|DRUG: NaCl 0.9%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Double-blind Study of Controlled Release OROS Hydromorphone Compared to Placebo in Patients With Chronic Osteoarthritis (OA) Pain
Status: COMPLETED
Conditions: Chronic Pain
Interventions: DRUG: OROS hydromorphone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics Investigation of GSK3335065 Intravenous (IV) Infusion in Healthy Adults
Status: TERMINATED
Conditions: Pancreatitis, Acute Necrotizing
Interventions: DRUG: GSK3335065|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Irinotecan and Cisplatin With or Without Amifostine in Treating Children With Solid Tumors That Have Not Responded to Previous Therapy
Status: COMPLETED
Conditions: Unspecified Childhood Solid Tumor, Protocol Specific
Interventions: DRUG: cisplatin|DRUG: irinotecan hydrochloride|DRUG: amifostine trihydrate|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized, Double-blind, Placebo-controlled, Multicenter, Cross-over Study to Assess the Effects of a 3 Week Therapy Each With QVA149 Versus Placebo on Pulmonary Function and Average Physical Activity Levels in Patients With COPD.
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: QVA149|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Symptom Assessment in Adult Patients With Erosive GERD (Gastroesophageal Reflux Disease) or enGERD (Endoscopic-negative GERD) After Treatment With Pantoprazole (BY1023/M3-343)
Status: COMPLETED
Conditions: GERD
Interventions: DRUG: Pantoprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chlorhexidine vs Lactobacillus Plantarum for Oral Care in Intubated ICU Patients
Status: COMPLETED
Conditions: Pathogenic Bacteria in the Oropharynx|Ventilator-associated Pneumonia
Interventions: PROCEDURE: Lactobacillus plantarum 299 for oral care|PROCEDURE: Chlorhexidine for standard oral care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Radiation and TSR-042 (Dostarlimab) in People With Endometrial Cancer After They Receive Surgery
Status: ACTIVE_NOT_RECRUITING
Conditions: Endometrial Cancer
Interventions: RADIATION: Intensity modulated radiation therapy (IMRT)|DRUG: Dostarlimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of High Flow Nasal Cannula Versus Continues Positive Airway Pressure in Adults With Obstructive Sleep Apnea
Status: UNKNOWN
Conditions: Sleep Apnea
Interventions: DEVICE: Continuous Positive Airway Pressure (CPAP)|DEVICE: High Flow Nasal Cannula (HFNC)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Efficacy and Safety of Orismilast in Psoriasis
Status: COMPLETED
Conditions: Psoriasis|Skin Diseases
Interventions: DRUG: Orismilast modified release tablets|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: [124I]FIAU PET-CT Scanning in Diagnosing Osteomyelitis in Patients With Diabetic Foot Infection
Status: TERMINATED
Conditions: Diabetic Foot Infection
Interventions: RADIATION: [124I]FIAU
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Combination Chemotherapy With or Without Filgrastim Before Surgery, High-Dose Chemotherapy, and Radiation Therapy Followed by Isotretinoin With or Without Monoclonal Antibody in Treating Patients With Neuroblastoma
Status: UNKNOWN
Conditions: Neuroblastoma
Interventions: BIOLOGICAL: filgrastim|BIOLOGICAL: monoclonal antibody Ch14.18|DRUG: busulfan|DRUG: carboplatin|DRUG: cyclophosphamide|DRUG: etoposide|DRUG: isotretinoin|DRUG: melphalan|DRUG: vincristine sulfate|PROCEDURE: bone marrow ablation with stem cell support|PROCEDURE: conventional surgery|PROCEDURE: peripheral blood stem cell transplantation|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Amiodarone and N-Acetylcysteine or Amiodarone Alone for Preventing Atrial Fibrillation After Thoracic Surgery
Status: ACTIVE_NOT_RECRUITING
Conditions: Thoracic Surgery|Atrial Fibrillation in High Risk Patients
Interventions: DRUG: Amiodarone|DRUG: N-Acetylcysteine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Association Between Obstructive Sleep Apnea, Facial Pigmentation, and Vasovagal Symptoms.
Status: RECRUITING
Conditions: Obstructive Sleep Apnea|Vasovagal Syncope|Smoking|Acanthosis Nigricans
Interventions: DIAGNOSTIC_TEST: In-lab polysomnography|DEVICE: Continuous positive airway pressure
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study to Evaluate the Efficacy and Safety of 3 Fixed Doses of Intranasal Esketamine in Addition to Comprehensive Standard of Care for the Rapid Reduction of the Symptoms of Major Depressive Disorder, Including Suicidal Ideation, in Pediatric Participants Assessed to be at Imminent Risk for Suicide
Status: COMPLETED
Conditions: Depressive Disorder, Major
Interventions: DRUG: Intranasal Placebo|DRUG: Midazolam Placebo Solution|DRUG: Midazolam|DRUG: Esketamine|DRUG: Esketamine|DRUG: Esketamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study to Evaluate the Safety and Effectiveness of Inclisiran Sodium in Indian Patients With Primary Hypercholesterolemia or Mixed Dyslipidemia
Status: NOT_YET_RECRUITING
Conditions: Primary Hypercholesterolemia|Mixed Dyslipidemia
Interventions: DRUG: inclisiran
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ffr-gUidance for compLete Non-cuLprit REVASCularization
Status: COMPLETED
Conditions: Coronary Artery Disease|ST-elevation Myocardial Infarction
Interventions: PROCEDURE: FFR Treatment Arm|OTHER: Conservative Treatment Arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Predict MDE Outcomes After MST
Status: COMPLETED
Conditions: Major Depressive Episode
Interventions: DEVICE: Magpro X100 + Option|DEVICE: ThymatronSystem Ⅳ Electroconvulsive System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Diltiazem on Coronary Artery Ectasia
Status: COMPLETED
Conditions: Coronary Artery Ectasia
Interventions: DRUG: intracoronary administration of diltiazem|DRUG: intracoronary injection of 5 mL saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Biomarkers in Urine for Children With Monosymptomatic Nocturnal Enuresis and Nocturnal Polyuria
Status: COMPLETED
Conditions: Nocturnal Enuresis
Interventions: DIAGNOSTIC_TEST: Urine collection through a collecting device (Uridome®) for maximum 1 week|DIAGNOSTIC_TEST: Urine collection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy of Rapamycin in the Treatment of Cervico-facial Lymphatic Malformations
Status: RECRUITING
Conditions: Lymphatic Malformation|Pediatric
Interventions: DRUG: rapamycin|DEVICE: MRI|BIOLOGICAL: Rapamycin dosage
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Evaluate Sperm Parameters in Men With Secondary Hypogonadism Previously Treated With Topical Testosterone
Status: COMPLETED
Conditions: Secondary Hypogonadism
Interventions: DRUG: 25 mg Androxal|DRUG: Testim 1%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Liwen Procedure in Obstructive Hypertrophic Cardiomyopathy on Arrhythmias
Status: ACTIVE_NOT_RECRUITING
Conditions: Hypertrophic Cardiomyopathy|Arrhythmia
Interventions: PROCEDURE: Percutaneous Intramyocardial Septal Radiofrequency Ablation for hypertrophic obstructive cardiomyopathy (Liwen Procedure)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: An Investigational Study to Determine the Drug Level Profile of BMS-986165 in Healthy Male Volunteers Following Transporter Inhibition.
Status: COMPLETED
Conditions: Healthy Male Volunteers
Interventions: DRUG: BMS-986165|DRUG: Pyrimethamine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Study of Plum-blossom Needling Enhancing Efficacy of Aminolevulinic Acid-photodynamic Therapy for Actinic Keratosis
Status: UNKNOWN
Conditions: Actinic Keratoses
Interventions: DEVICE: PBN
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Humoral and Cellular Immunity of Low and High-responders After Tick-borne Encephalitis Vaccination
Status: COMPLETED
Conditions: Tick-borne Encephalitis
Interventions: BIOLOGICAL: TBE vaccination and influenza vaccination
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Different Modalities of Analgesia in Open Heart Surgeries in Mansoura University
Status: UNKNOWN
Conditions: Coronary Artery Disease|Valve Disease, Heart|Pain, Acute|Pain, Postoperative
Interventions: DRUG: Fentanyl|DRUG: Fentanyl, Propofol|DRUG: Dexmedetomidine, Ketamine, Magnesium sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Visuomotor Training Using Pablo System on Hand Function in Children With Hemiplegic Cerebral Palsy
Status: COMPLETED
Conditions: Cerebral Palsy
Interventions: OTHER: Traditional Treatment Program|OTHER: Virtual Reality Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of DITPA in Patients With Congestive Heart Failure
Status: TERMINATED
Conditions: Heart Failure, Congestive
Interventions: DRUG: DITPA (3,5-diiodothyropropionic acid)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Feasibility Study Evaluating the Use of a Non-invasive Ventilation Mask
Status: COMPLETED
Conditions: Noninvasive Ventilation|Respiratory Insufficiency
Interventions: DEVICE: Oro-nasal Mask
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Percutaneous High Frequency Alternating Current Stimulation in Healthy Volunteers
Status: COMPLETED
Conditions: Electrical Stimulation|Neuromodulation
Interventions: DEVICE: 10 kHz stimulation (Myomed 932, Enraf-Nonius)|DEVICE: 20 kHz stimulation (Myomed 932, Enraf-Nonius)|DEVICE: Sham stimulation (Myomed 932, Enraf-Nonius)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Early Inspiratory Muscle Training in Lung Transplanted Patients
Status: RECRUITING
Conditions: Lung Transplant Recipients|Muscle Weakness|Respiratory Insufficiency|Pulmonary Rehabilitation|Chronic Lung Disease
Interventions: DEVICE: Threshold load device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Active-Controlled Study to Assess the Efficacy and Safety of DFD-05 in Subjects With Common Warts
Status: COMPLETED
Conditions: Common Warts
Interventions: DRUG: DFD05 Cream|DRUG: Active01 Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study in Cognitively Intact Seniors Aiming to Assess the Effects of Meditation Training
Status: UNKNOWN
Conditions: Cognitive Aging
Interventions: OTHER: Meditation practice|OTHER: Learning English as a foreign language
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety, Tolerability, Pharmacokinetics and Preliminary Antitumor Activity of Escalating Doses of SIM0348 as a Single Agent in Advanced Solid Tumors
Status: NOT_YET_RECRUITING
Conditions: Advanced Solid Tumors
Interventions: DRUG: SIM0348|DRUG: SIM0348
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect Of Cervical Mobilization And Clinical Pilates in Cervicogenic Headache
Status: COMPLETED
Conditions: Headache, Cervicogenic|Exercise|Therapeutics
Interventions: OTHER: manuel therapy|OTHER: exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of Recombinant Humanized CTLA-4-FC Fusion Protein Injection in Healthy Subjects
Status: RECRUITING
Conditions: Health Volunteer
Interventions: BIOLOGICAL: Recombinant human CTLA-4-FC fusion protein for injection 1mg/kg|BIOLOGICAL: Recombinant human CTLA-4-FC fusion protein for injection 2.5mg/kg|BIOLOGICAL: Recombinant human CTLA-4-FC fusion protein for injection 5mg/kg|BIOLOGICAL: Recombinant human CTLA-4-FC fusion protein for injection 7.5mg/kg|BIOLOGICAL: Recombinant human CTLA-4-FC fusion protein for injection 10mg/kg|BIOLOGICAL: Placebo-1mg/kg|BIOLOGICAL: Placebo-2.5mg/kg|BIOLOGICAL: Placebo-5mg/kg|BIOLOGICAL: Placebo-7.5mg/kg|BIOLOGICAL: Placebo-10mg/kg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Losmapimod Safety and Efficacy in COVID-19
Status: TERMINATED
Conditions: COVID-19
Interventions: DRUG: Losmapimod oral tablet|DRUG: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Oral Lipid Ingestion in Relation to Ovarian Androgen Secretion in Polycystic Ovary Syndrome (PCOS)
Status: TERMINATED
Conditions: Polycystic Ovary Syndrome
Interventions: DRUG: Salsalate|DRUG: Salsalate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Reversal of Complete Heart Block With Aminophylline in Inferior Wall Myocardial Infarction Patients
Status: NOT_YET_RECRUITING
Conditions: Complete Heart Block|Inferior Wall Myocardial Infarction
Interventions: DRUG: Aminophylline Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Convulsive Therapies During Continuation
Status: RECRUITING
Conditions: Depression|Bipolar Depression|Unipolar Depression|Treatment Resistant Depression
Interventions: DEVICE: Magnetic Seizure Therapy (MST)|DEVICE: RUL-UB ECT|DEVICE: Bitemporal ECT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of ZD6474 and Faslodex in Non-Small Cell Lung Cancer
Status: WITHDRAWN
Conditions: Carcinoma, Non Small Cell Lung
Interventions: DRUG: ZD6474 (vandetanib)|DRUG: Faslodex (Fulvestrant)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Compare U0267 Against Vehicle in Subjects With Plaque-type Psoriasis One of Two Phase 3 Studies
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: U0267|DRUG: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess Dasatinib in Patients With Core Binding Factors Acute Myelogenous Leukemia
Status: COMPLETED
Conditions: Acute Myelogenous Leukemia
Interventions: DRUG: dasatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Comparison of Beverages Consumed Within a Meal to Satiation on Meal-time Food Intake and Post-meal Appetite and Glycemic Response in Healthy Young Adults
Status: COMPLETED
Conditions: Obesity|Hyperglycemia
Interventions: OTHER: Nutritional Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Clinical Efficacy of Laryngeal Mask Airway in Elderly Patients: Comparison With Young Adults
Status: COMPLETED
Conditions: Minor Urologic Surgery|Lower Extremity Surgery
Interventions: PROCEDURE: classic LMA insertion
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of HAIC in Combination With TQB2868 and Ramucirumab for Second-line Treatment of Advanced Hepatocellular Carcinoma
Status: NOT_YET_RECRUITING
Conditions: Hepatocellular Carcinoma，Bispecific Antibodies, HAIC, Ramucirumab
Interventions: DRUG: HAIC（Oxaliplatin+ Raltitrexed）、TQB2868、Ramucirumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety of Griffithsin in a Carrageenan Gel in Healthy Women
Status: COMPLETED
Conditions: HIV Infection
Interventions: DRUG: Griffithsin Gel|DRUG: Placebo Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of Free Combination of Tiotropium + Formoterol Compared to Formoterol and Tiotropium in Patients With Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Tiotropium + formoterol combination|DRUG: Tiotropium|DRUG: Formoterol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Study of Tarceva (Erlotinib) in Combination With Platinum Based Chemotherapy in Patients With Non-Small Cell Lung Cancer.
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: erlotinib [Tarceva]|DRUG: placebo|DRUG: gemcitabine|DRUG: cisplatin|DRUG: carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Sun-like Spectrum With Different Spectrum Composition on Retinal Blood Flow
Status: RECRUITING
Conditions: Myopia
Interventions: DEVICE: Shorter-wavelength dominant light|DEVICE: Light similar to the solar spectrum proportion|DEVICE: Longer-wavelength dominant light
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Point-of-care Tests for the Diagnosis of Cutaneous Leishmaniasis in Afghanistan
Status: COMPLETED
Conditions: Cutaneous Leishmaniases
Interventions: DIAGNOSTIC_TEST: LoopampTM Leishmania Detection Kit|DIAGNOSTIC_TEST: CL DetectTM Rapid Test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Nexplanon Application Post-Abortion (NAPA)
Status: COMPLETED
Conditions: Contraception|Abortion, Therapeutic
Interventions: OTHER: Immediate Nexplanon Insertion|OTHER: Post-op Nexplanon Insertion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Randomized Controlled Trial Comparing Closed-suction Drain Versus Passive Gravity Drain Following Pancreatic Resection
Status: COMPLETED
Conditions: Pancreaticoduodenectomy|Distal Pancreatectomy
Interventions: PROCEDURE: Closed gravity drain|PROCEDURE: closed suction drain
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Music and Speech Perception in New Cochlear Implanted Subjects Using or Not a Tonotopy Based Fitting
Status: COMPLETED
Conditions: Sensorineural Hearing Loss, Bilateral
Interventions: DEVICE: tonotopy based fitting then default fitting|DEVICE: default fitting then tonotopy based fitting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Natural Dentition, Prosthesis and Antagonist Wear 3D Analysis
Status: RECRUITING
Conditions: Wear, Tooth|Dental Prosthesis Complication|Wear, Occlusal
Interventions: DEVICE: Monolithic Zirconia|DEVICE: Hybrid-Acrylic|BEHAVIORAL: Dentate Patients
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Photobiomodulation on Insomnia in the Elderly: Clinical Trials of Phototherapy Devices
Status: RECRUITING
Conditions: Photobiomodulation
Interventions: DEVICE: Bright light|DEVICE: Near-infrared light|DEVICE: Bright light+ near-infrared light
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Mesh and Mesh Fixation in Laparoscopic Groin Hernia Surgery
Status: COMPLETED
Conditions: Hernia, Inguinal|Surgical Mesh|Laparoscopy|Hernia|Hernia, Femoral|Surgical Procedures, Minimally Invasive|Surgical Staplers|Recurrence|Fixation Device; Complications
Interventions: PROCEDURE: TEP|PROCEDURE: TAPP
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Assessment of Radial Artery Complications Whilst Achieving Rapid Haemostasis
Status: TERMINATED
Conditions: Injury; Blood Vessel, Wrist, Radial Artery
Interventions: DEVICE: Haemostatic Dressing|DEVICE: Conventional Dressing|DEVICE: 120 Minutes External Compression|DEVICE: 60 Minutes External Compression
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating a Coparenting Breastfeeding Support Intervention
Status: COMPLETED
Conditions: Parenting|Breastfeeding
Interventions: BEHAVIORAL: Coparenting Breastfeeding Support Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating the Safety and the Efficacy of Combination of Atezolizumab, Tiragolumab and and Stereotactic Body Radiation Therapy in Patients With Oligometastatic Multiorgan (IMMUNOs-SBRT)
Status: RECRUITING
Conditions: Metastatic Non Small Cell Lung Cancer|Metastatic Bladder Cancer|Metastatic Renal Cell Carcinoma|Metastatic Head and Neck Cancer
Interventions: DRUG: Atezolizumab 60 MG/1 ML Intravenous Solution [TECENTRIQ]|DRUG: Tiragolumab|RADIATION: Stereotactic body radiation therapy (SBRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Lu AG06466 for the Treatment of Spasticity in Participants With Multiple Sclerosis
Status: TERMINATED
Conditions: Multiple Sclerosis
Interventions: DRUG: Lu AG06466|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dentoskeletal Effects of Two Different Fixed Functional Appliances for Correction of Class II Malocclusion: A Comparative Clinical Study
Status: COMPLETED
Conditions: Class II Malocclusion
Interventions: DEVICE: Mandibular Protraction Appliance|DEVICE: PowerScope Appliance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fed Study of Olmesartan Medoxomil Tablets 40 mg and Benicar® Tablets 40 mg
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Olmesartan Medoxomil Tablets 40 mg|DRUG: Benicar® Tablets 40 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study of EUR-1066 in Subjects With Chronic Pancreatitis, Exocrine Pancreatic Insufficiency and Chronic Abdominal Pain
Status: TERMINATED
Conditions: Chronic Pancreatitis
Interventions: DRUG: EUR-1066-A|DRUG: Zenpep|DRUG: EUR-1066-B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Class IV Laser Therapy on Ejection Fraction, Cardio Biomarkers and Functional Outcomes
Status: RECRUITING
Conditions: Acute Coronary Syndrome
Interventions: RADIATION: Class IV Laser|RADIATION: Sham Class IV Laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Physical Dependence Study in Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: LY2140023|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of HIV Clinic-based Treatment With Buprenorphine Versus Referred Care in Heroin-dependent Participants
Status: COMPLETED
Conditions: Opiate Dependence|HIV Seropositivity|HIV Infections
Interventions: BEHAVIORAL: Clinic-based substance abuse treatment with buprenorphine|BEHAVIORAL: Case management and referred substance abuse treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized Trial of Rosuvastatin in Elective Angioplasty to Prevent Contrast-induced Nephropathy (CLEAR-CIN).
Status: COMPLETED
Conditions: Nephropathy
Interventions: DRUG: Rosuvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Umbilical Cord Blood T-Regulatory Cell Infusion Followed by Donor Umbilical Cord Blood Transplant in Treating Patients With High-Risk Leukemia or Other Hematologic Diseases
Status: TERMINATED
Conditions: Graft Versus Host Disease|Leukemia|Lymphoma|Multiple Myeloma and Plasma Cell Neoplasm|Myelodysplastic Syndromes|Secondary Myelofibrosis
Interventions: DRUG: cyclophosphamide|DRUG: cyclosporine|DRUG: fludarabine phosphate|DRUG: mycophenolate mofetil|PROCEDURE: Treg cell infusion|PROCEDURE: umbilical cord blood transplantation|RADIATION: total-body irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study in Patients With Diabetes Mellitus Type II of the Effect on Albuminuria of 24 Week Treatment With Valsartan, Benazepril, and Valsartan+Benazepril
Status: TERMINATED
Conditions: Hypertension|Diabetic Nephropathy
Interventions: DRUG: valsartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of BMS-708163
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: BMS-708163|DRUG: BMS-708163|DRUG: Placebo|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Lactobacillus GG Supplementation During Pediatric Burn Injuries
Status: TERMINATED
Conditions: Burns
Interventions: DRUG: Lactobacillus GG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Seattle Social Development Project: An Implementation of the Raising Healthy Children Intervention
Status: COMPLETED
Conditions: Adolescent Health|Adolescent Problem Behavior
Interventions: BEHAVIORAL: The Raising Healthy Children intervention, including teacher training, child skill development, and parent training
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Iray for Vascularized Pigment Epithelial Detachment (VPED) Secondary to Age Related Macular Degeneration
Status: UNKNOWN
Conditions: Retinal Pigment Epithelial Detachment With Vascularization|Age Related Macular Degeneration
Interventions: RADIATION: Iray|DRUG: Lucentis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Impact of Touch Relaxation in Sedated Intubated Patients Hospitalized in Intensive Care at Niort Hospital
Status: RECRUITING
Conditions: Reaction Anxiety|Difficult or Failed Intubation
Interventions: OTHER: this arm will received relaxing touch (hands, feet, head) during 30 minutes twice a day
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Outpatient Biofeedback in Addition to Home Pelvic Floor Muscle Exercises
Status: COMPLETED
Conditions: Urinary Incontinence, Stress
Interventions: OTHER: PFMT with biofeedback + Home PFMT|OTHER: PFMT without biofeedback + Home PFMT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Three Different Antibiotic Treatments Against Recurrent Urinary Tract Infections in Catheterized Patients
Status: NOT_YET_RECRUITING
Conditions: Recurrent Urinary Tract Infections|Chronic Urinary-catheter-carrier|Biofilm Infection|Antibiotic Treatment|Replacement of Urinary Catheter
Interventions: COMBINATION_PRODUCT: Antibiotic combination therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase III Trial Evaluating Fruquintinib Efficacy and Safety in 3+ Line Colorectal Cancer Patients （FRESCO)
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: fruquintinib|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT