pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: SCH 727965 in Patients With Mantle Cell Lymphoma or B-Cell Chronic Lymphocytic Leukemia (Study P04715)
Status: TERMINATED
Conditions: Lymphoma, Mantle-Cell|Leukemia, Lymphocytic, Chronic, B-Cell
Interventions: DRUG: SCH 727965|DRUG: Bortezomib|BIOLOGICAL: Alemtuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Topical Diclofenac on Clinical Outcome in Breast Cancer Patients Treated With Capecitabine
Status: COMPLETED
Conditions: Hand and Foot Syndrome
Interventions: DRUG: (CARBAMIDE®)|DRUG: (VOLTAREN®) Emulgel 1%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Effects of Multidomain Training of Health With Aging (Train-Old)
Status: UNKNOWN
Conditions: Sarcopenia|Memory Loss|Muscular Atrophy|Cardiovascular Diseases|Frailty
Interventions: PROCEDURE: Multidomain training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Alcoholic Chlorhexidine Compared to Povidone Iodine to Limit Perineural Catheter Colonisation
Status: UNKNOWN
Conditions: Infection of Catheter Exit Site|Catheter Related Infection
Interventions: PROCEDURE: perineural catheterization implementation|DRUG: 2% alcoholic chlorhexidine|DRUG: povidon iodine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: CMC (Carpometacarpal) OA (Osteoarthritis) Thumb Splint Study
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DEVICE: Comfort Cool thumb splint by North Coast Medical|DEVICE: Custom made thermoplastic & neoprene splint
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low Dose Naltrexone-buprenorphine Transfer to Vivitrol Injection in Opioid Dependence
Status: COMPLETED
Conditions: Opiate Dependence
Interventions: DRUG: very low dose naltrexone|DRUG: extended release naltrexone|DRUG: buprenorphine/naloxone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Grazoprevir/Elbasvir for Treatment of Hepatitis C Virus Genotype 4 Post Kidney Transplant
Status: UNKNOWN
Conditions: Hepatitis C
Interventions: DRUG: Grazoprevir/Elbasvir
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: efficAcy and Safety of Home-baSed Cardiac rehabIlitation in ChineSe Revascularized patienTs
Status: UNKNOWN
Conditions: Coronary Artery Disease
Interventions: OTHER: home-based cardiac rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Dextenza in Patients With Ocular GVHD and Effects on Ocular Surface Disease Outcomes
Status: WITHDRAWN
Conditions: Graft Vs Host Disease
Interventions: DRUG: DEXTENZA (dexamethasone ophthalmic insert) 0.4 mg, for intracanalicular use|DEVICE: Regular dissolvable intracanalicular plug
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study Assessing Stereotactic Radiotherapy in Therapeutic Strategy of Oligoprogressive Renal Cell Carcinoma Metastases
Status: RECRUITING
Conditions: Metastatic Renal Cell Carcinoma|Radiotherapy
Interventions: RADIATION: Steretactic radiotherapy|DRUG: Pursuit of ongoing systemic treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of ALH-L1005 in Patients With Chronic Periodontitis
Status: COMPLETED
Conditions: Chronic Periodontitis
Interventions: DRUG: ALH-L1005 600mg/day|DRUG: ALH-L1005 1,200mg/day|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing the Closed Triple Therapy, Open Triple Therapy and a Dual Therapy for Effect on Lung Function in Subjects With Chronic Obstructive Pulmonary Disease (COPD)
Status: WITHDRAWN
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Fluticasone furoate 100 mcg + Umeclidinium 62.5 mcg+Vilanterol 25 mcg|DRUG: Fluticasone furoate 100 mcg + Vilanterol 25 mcg|DRUG: Umeclidinium 62.5 mcg|DEVICE: Placebo ELLIPTA inhaler|DRUG: Albuterol/Salbutamol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Jiuweihuaban Pill for Treating Plaque Psoriasis
Status: RECRUITING
Conditions: Plaque Psoriasis
Interventions: DRUG: Jiuweihuaban Pill placebo|DRUG: low dose Jiuweihuaban Pill|DRUG: high dose Jiuweihuaban Pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Progressive Mobility Program and Technology to Improve the Level of Physical Activity and Functionality of ICU Patients
Status: COMPLETED
Conditions: Critical Illness|Muscle Weakness
Interventions: OTHER: Conventional Physical Therapy|OTHER: Early and progressive mobilization program|OTHER: Respiratory therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Ranibizumab Monotherapy and Ranibizumab Combination Therapies in Recurrent or Persistent Choroidal Neovascularization Secondary to Age-related Macular Degeneration
Status: COMPLETED
Conditions: Age-Related Macular Degeneration|Neovascularization, Choroidal
Interventions: DRUG: Intravitreal dexamethasone and intravitreal ranibizumab|DRUG: Intravitreal ranibizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of High-intensity Interval Training in Combination With Side-alternating Whole-body Vibration
Status: COMPLETED
Conditions: Health Behavior
Interventions: OTHER: 4x4 min HIT|OTHER: 4x4 min HIT + WBV (18 Hz)|OTHER: 4x4 min HIT + (30 Hz)|OTHER: whole-body vibration at 30 Hz
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Prevention of Hypotension After Epidural Analgesia After Major Surgery
Status: COMPLETED
Conditions: Hypotension|Pain
Interventions: DRUG: Ropivacaine|DRUG: Epinephrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: 2% Lidocaine Plus 0.5% Bupivacaine Versus 0.5% Bupivacaine in Brachial Block for Creation of Arteriovenous (AV) Fistula
Status: UNKNOWN
Conditions: Infraclavicular Brachial Plexus Block
Interventions: DRUG: Bupivacaine plus lidocaine|DRUG: Bupivacaine 30 ml
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 18F-FDG Metabolism Imaging Monitoring Non-small Cell Lung Cancer Curative Effect of Chemotherapy Multicenter Clinical Study
Status: UNKNOWN
Conditions: Non-small-cell Lung Cancer
Interventions: RADIATION: 18F-FDG
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation of an Intervention to Increase Colorectal Cancer Screening in Primary Care Clinics
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: BEHAVIORAL: Usual care|BEHAVIORAL: Clinic-focused intervention|BEHAVIORAL: Clinic- and patient-focused
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Tobacco, Alcohol and Cancerization of the Oral Mucosa (TACO)
Status: RECRUITING
Conditions: Oral Squamous Cell Carcinomas
Interventions: PROCEDURE: Cytobrush sample|PROCEDURE: Blood sampling
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluating in Vivo AZA Incorporation in Mononuclear Cells Following Vidaza or CC486
Status: COMPLETED
Conditions: Myelodysplastic Syndromes|Acute Myeloid Leukemia|Chronic Myelomonocytic Leukemia
Interventions: DRUG: Azacitidine|DRUG: CC-486
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prophylactic Effect of Nirmatrelvir/Ritonavir and Ursodeoxycholic Acid on Reducing Complications After Cardiac Surgery
Status: ACTIVE_NOT_RECRUITING
Conditions: Cardiac Surgery
Interventions: DRUG: Nirmatrelvir/ritonavir|DRUG: Ursodeoxycholic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Hematopoietic Stem Cell Transplantation (HSCT) Using CD34 Selected Mismatched Related Donor and One Umbilical Cord Unit
Status: TERMINATED
Conditions: Leukemia, Lymphocytic, Acute|Leukemia, Lymphocytic, Chronic|Leukemia, Myelocytic, Acute|Leukemia, Myeloid, Chronic|Lymphoma, Non-Hodgkin|Lymphoma, Hodgkins
Interventions: BIOLOGICAL: Haploidentical/cord transplant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Anesthesia Technique on Early Outcome in Diabetic Patients Undergoing Lower Extremity Amputation
Status: UNKNOWN
Conditions: Diabetic Foot
Interventions: DRUG: General anesthesia|DRUG: Peripheral nerve block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assisting HIV-infected Mothers in Disclosing Their Serostatus to Their Children
Status: COMPLETED
Conditions: HIV
Interventions: BEHAVIORAL: Teaching, Raising, and Communicating with Kids (TRACK)|OTHER: Treatment as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: GH, IGF-I and Somatostatin Analogues in Hepatocellular Carcinoma
Status: COMPLETED
Conditions: Advanced Hepatocellular Carcinoma
Interventions: DRUG: Octreotide-LAR, Lanreotide Autogel|OTHER: Locoregional treatments
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of a Component of Fish Oil on Exercise-Induced Bronchoconstriction and Airway Inflammation in Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DIETARY_SUPPLEMENT: Docosahexaenoic Acid|DIETARY_SUPPLEMENT: Placebo Docosahexaenoic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate OXERVATE™ in Patients With Stage 1 Neurotrophic Keratitis
Status: COMPLETED
Conditions: Neurotrophic Keratitis
Interventions: DRUG: cenegermin-bkbj
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I Trial of Gene Vector to Patients With Retinal Disease Due to RPE65 Mutations
Status: ACTIVE_NOT_RECRUITING
Conditions: Amaurosis of Leber|Retinal Diseases
Interventions: GENETIC: rAAV2-CBSB-hRPE65
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Informed Decision Making Intervention in Screening for Prostate Cancer of Predominantly African American Participants in a Community Outreach Program
Status: TERMINATED
Conditions: Prostate Carcinoma
Interventions: OTHER: Educational Intervention|PROCEDURE: digital rectal examination|OTHER: Pre-test administration|OTHER: Survey Administration|OTHER: Prostate-specific antigen measurement|OTHER: Post test administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: The In Vitro Fertilization - Lipiodol Uterine Bathing Effect Study
Status: UNKNOWN
Conditions: Endometriosis|In Vitro Fertilization Implantation Failure
Interventions: PROCEDURE: Lipiodol + IVF|PROCEDURE: IVF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial Comparing SGC and Conventional Empiric Treatment for Glucose Control in Critically Ill Patients With Mechanical Ventilation in ICU
Status: UNKNOWN
Conditions: Hyperglycemia|Respiratory Failure|Critical Illness
Interventions: PROCEDURE: conventional empirical glycemic control|PROCEDURE: SGC directed glycemic control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acarbose and Prandial Insulin for the Treatment of Gestational Diabetes Mellitus.
Status: TERMINATED
Conditions: Gestational Diabetes Mellitus in Pregnancy
Interventions: DRUG: Acarbose|DRUG: Prandial insulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Topical PH-10 Aqueous Hydrogel and Photodynamic Therapy for Psoriasis
Status: TERMINATED
Conditions: Plaque Psoriasis
Interventions: DRUG: PH-10 (rose bengal disodium 0.001%)|DRUG: PH-10 (rose bengal disodium 0.001%)|DRUG: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PK and PD of Sequential Multiple Ascending, Repeat Doses of Oral CXA-10 in Healthy Obese Male Subjects
Status: COMPLETED
Conditions: Acute Kidney Injury
Interventions: DRUG: CXA-10|OTHER: CXA-10 placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of 2.0 mg Ranibizumab in Subjects With Ischemic Central Retinal Vein Occlusion (RAVE2)
Status: TERMINATED
Conditions: Ischemia|Retinal Vein Occlusion|Pathologic Processes|Retinal Diseases|Eye Diseases
Interventions: DRUG: ranibizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testing the Addition of Lenalidomide and Nivolumab to the Usual Treatment for Primary CNS Lymphoma
Status: RECRUITING
Conditions: Primary Diffuse Large B-Cell Lymphoma of the Central Nervous System
Interventions: PROCEDURE: Bone Marrow Aspiration and Biopsy|PROCEDURE: Computed Tomography|PROCEDURE: Echocardiography|DRUG: Lenalidomide|PROCEDURE: Lumbar Puncture|PROCEDURE: Magnetic Resonance Imaging|DRUG: Methotrexate|BIOLOGICAL: Nivolumab|PROCEDURE: Positron Emission Tomography|BIOLOGICAL: Rituximab|PROCEDURE: Ultrasound Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess Ebola Vaccines ChAd3-EBO-Z and Ad26.ZEBOV
Status: COMPLETED
Conditions: Ebola Virus Disease
Interventions: BIOLOGICAL: ChAd3-EBO-Z|BIOLOGICAL: Ad26.ZEBOV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Neoadjuvant Adriamycin and Ifosfamide Plus High-Dose ICE in Patients With Soft Tissue Sarcoma (STS)
Status: COMPLETED
Conditions: Sarcoma, Soft Tissue
Interventions: DRUG: Adriamycin|DRUG: Ifosfamide|DRUG: Etoposide|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Picoplatin in Colorectal Cancer
Status: UNKNOWN
Conditions: Colorectal Cancer
Interventions: DRUG: (FOLPI) Picoplatin with 5-FU and Leucovorin|DRUG: FOLPI|DRUG: FOLFOX
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long-term Safety of BCX9930 in Participants With Paroxysmal Nocturnal Hemoglobinuria
Status: ACTIVE_NOT_RECRUITING
Conditions: Paroxysmal Nocturnal Hemoglobinuria
Interventions: DRUG: BCX9930
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Bipolar Disorders and Retinal Electrophysiological Markers
Status: TERMINATED
Conditions: Bipolar Disorder
Interventions: DEVICE: EEG and ERG measurements (Retinaute®, BioSerenity)|DEVICE: Actigraphy (Motion Watch 8®, CamNtech)|BEHAVIORAL: Neuropsychological assessments|DEVICE: Optical Coherence Tomography (OCT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Erlotinib in Treating Patients With Unresectable Liver Cancer and Liver Dysfunction
Status: COMPLETED
Conditions: Adult Primary Hepatocellular Carcinoma|Advanced Adult Primary Liver Cancer|Localized Unresectable Adult Primary Liver Cancer|Recurrent Adult Primary Liver Cancer
Interventions: DRUG: erlotinib hydrochloride|OTHER: pharmacological study|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical and Biological Outcomes of Human Milk and Formula Intake After Gastroschisis Repair
Status: COMPLETED
Conditions: Gastroschisis
Interventions: DIETARY_SUPPLEMENT: Enteral Intake - Human Milk|DIETARY_SUPPLEMENT: Enteral Intake - Formula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exer-gaming on Upper Extremity Function and Activities of Daily Living in Sub-acute Stroke Patient.
Status: COMPLETED
Conditions: Stroke|Cardiovascular Stroke|Cerebrovascular Accident
Interventions: OTHER: Control group|OTHER: Experimental Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Donor Peripheral Stem Cell Transplant in Treating Patients With Relapsed Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Leukemia
Interventions: BIOLOGICAL: aldesleukin|BIOLOGICAL: therapeutic allogeneic lymphocytes|DRUG: cyclophosphamide|DRUG: fludarabine phosphate|PROCEDURE: in vitro treated peripheral blood stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bulking Agent Versus Electrostimulation Therapy in Anal Incontinence
Status: UNKNOWN
Conditions: Fecal Incontinence
Interventions: PROCEDURE: Bulking agent|PROCEDURE: Endoanal electrostimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Palpitate-Eluting Balloon Angioplasty in the Treatment of Coronary Bifurcation Lesion Evaluated by OCT
Status: UNKNOWN
Conditions: Angioplasty|Percutaneous Coronary Intervention
Interventions: DEVICE: Paclitaxel-Eluting Balloon
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Estimation of Pentraxin3 and PGingivalis Levels in Patients With Knee Joint and Gum Diseases
Status: COMPLETED
Conditions: Rheumatoid Arthritis|Chronic Periodontitis
Interventions: OTHER: Estimation of Pentraxin3|GENETIC: Estimation of P.Gingivalis levels
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: VISTA-16 Trial: Evaluation of Safety and Efficacy of Short-term A-002 Treatment in Subjects With Acute Coronary Syndrome
Status: TERMINATED
Conditions: Acute Coronary Syndrome
Interventions: DRUG: A-002, varespladib methyl|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Immunohistochemical Evaluation of DNA Methylation and Histone Modification in H. Pylori Associated Gastric Carcinoma
Status: RECRUITING
Conditions: Gastric Carcinoma
Interventions: DIAGNOSTIC_TEST: Immunohistochemical staining for DNMT1 and EZH2
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical Assessment Of GW815SF Salmeterol/Fluticasone Propionate(HFA MDI) In Pediatric Patients With Bronchial Asthma -A Long Term (24-week) Study-
Status: COMPLETED
Conditions: Bronchial Asthma
Interventions: DRUG: GW815SF Salmeterol/Fluticasone propionate(HFA MDI)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Denture Base Adaptation and Per-iimplant Tissue Health Between CAD and CAM Implant Overdenture
Status: COMPLETED
Conditions: Periimplantitis
Interventions: DEVICE: subtractive technique|DEVICE: additive technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Clinical Study to Evaluate the Long Term Efficacy, Safety and Tolerability of Miglustat in Patients With Stable Type 1 Gaucher Disease
Status: COMPLETED
Conditions: Gaucher Disease Type 1
Interventions: DRUG: Miglustat
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Analgesic İmpacts of Piroxicam and Diclofenac Sodium in the Treatment of Primary Dysmenorrhea
Status: COMPLETED
Conditions: Primary Dysmenorrhea
Interventions: DRUG: Piroxicam|DRUG: Diclofenac Sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Acute Effects of Medium Chain Triglyceride (MCT) Nutritional Ketosis on Parkinson's Disease (PD) Symptoms and Biomarkers (MCT-PD)
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DIETARY_SUPPLEMENT: Liquigen MCT oil|OTHER: Standard American Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: MK-0954A in Japanese Patients With Essential Hypertension Not Adequately Controlled With Losartan (MK-0954A-352)
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: MK-0954A|DRUG: Losartan|DRUG: Placebo to MK-0954A|DRUG: Placebo to losartan 100 mg|DRUG: Placebo to losartan 50 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: TGNB CARE Mentalizing-Focused Parenting Groups (TGNB-CARE)
Status: RECRUITING
Conditions: Parent-Child Relations
Interventions: OTHER: TGNB-CARE (Connecting and Reflecting Experience)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Cerebellum as a Potential Treatment Site for PD Motor Symptoms
Status: UNKNOWN
Conditions: Parkinson's Disease
Interventions: DEVICE: Magstim Rapid 2 Repetitive Transcranial Magnetic Stimulation|DEVICE: Magstim Rapid 2 Sham Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neuromodulation of Spinal Locomotor Circuitry to Elicit Stepping After Pediatric Spinal Cord Injury
Status: ENROLLING_BY_INVITATION
Conditions: Spinal Cord Injuries
Interventions: DEVICE: Biostim-5 transcutaneous spinal stimulator|OTHER: Transcutaneous Spinal Stimulator + Activity Based Locomotor Training
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Modality Augmentation for Navigation: Intuitive Fusion With Optical Lightweight Device (US/CBCT)
Status: WITHDRAWN
Conditions: Hepatic Biopsy or Ablation
Interventions: DEVICE: CBCT-US Fusion Arm|PROCEDURE: Hepatic Biopsy or Ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Dexmedetomidine Versus Clonidine in TAP Block
Status: COMPLETED
Conditions: Transversus Abdominis Plane Block
Interventions: DRUG: Dexmedetomidine|DRUG: Clonidine|DRUG: Levobupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of Mitapivat in Participants With Sickle Cell Disease and Nephropathy
Status: NOT_YET_RECRUITING
Conditions: Sickle Cell Disease|Nephropathy
Interventions: DRUG: Mitapivat
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of FDG PET and Bone Scintigraphy/Labelled Leukocyte/Gallium Scintigraphy in Diabetic Foot Osteomyelitis
Status: TERMINATED
Conditions: Diabetic Foot Infection
Interventions: DIAGNOSTIC_TEST: 18F-FDG PET-CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effectivity and Safety of Combination of Spent Grain Wax, Argan Oil, Shea Butter and Saccharide Isomerate
Status: UNKNOWN
Conditions: Acne Vulgaris
Interventions: DRUG: Combination cream|DRUG: Placebo cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vaccine Therapy Plus Biological Therapy in Treating Patients With Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: BIOLOGICAL: GPI-0100|BIOLOGICAL: MUC-2-Globo H-KLH conjugate vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cisplatin, Paclitaxel, and Everolimus in Treating Patients With Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: cisplatin|DRUG: everolimus|DRUG: paclitaxel|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acupuncture Chemotherapy-Induced Peripheral Neuropathy (CIPN) IRG
Status: TERMINATED
Conditions: Breast Cancer
Interventions: PROCEDURE: Acupuncture|BEHAVIORAL: Questionnaires|OTHER: Hand Function and Balance Tests
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Extensively Hydrolyzed Formula: Hypoallergenicity
Status: COMPLETED
Conditions: Food Hypersensitivity
Interventions: OTHER: Extensively hydrolyzed, whey protein infant formula|OTHER: Extensively hydrolyzed, casein protein infant formula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study to Investigate the Effects Single Oral Dose of AZD1386 (Capsaicin)
Status: COMPLETED
Conditions: Capsaicin Evoked Pain|Heat Sensitivity
Interventions: DRUG: AZD1386|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Engineered Donor Stem Cell Transplant in Treating Patients With Hematologic Malignancies
Status: COMPLETED
Conditions: Acute Lymphoblastic Leukemia|Acute Myeloid Leukemia|Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome|Aplastic Anemia|Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive|Chronic Myelomonocytic Leukemia|Chronic Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive|Lymphoblastic Lymphoma|Myelodysplastic Syndrome|Myeloproliferative Neoplasm|Plasma Cell Myeloma|Recurrent Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma|Recurrent Hodgkin Lymphoma|Recurrent Non-Hodgkin Lymphoma|Recurrent Plasma Cell Myeloma|Therapy-Related Myelodysplastic Syndrome
Interventions: DRUG: Cyclophosphamide|BIOLOGICAL: Filgrastim|DRUG: Fludarabine Phosphate|OTHER: Laboratory Biomarker Analysis|DRUG: Melphalan|PROCEDURE: Peripheral Blood Stem Cell Transplantation|BIOLOGICAL: Rituximab|DRUG: Tacrolimus|RADIATION: Total-Body Irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of All-Oral Combination of Narlaprevir/Ritonavir and Daclatasvir in Treatment-Naїve Patients With Chronic Hepatitis C Genotype 1b
Status: COMPLETED
Conditions: Chronic Hepatitis C Genotype 1b
Interventions: DRUG: Narlaprevir|DRUG: Ritonavir|DRUG: Daclatasvir
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High Dose Versus Standard Dose Proton Pump Inhibitor (PPI) in High-risk Bleeding Peptic Ulcers After Combined Endoscopic Treatment
Status: UNKNOWN
Conditions: Endoscopy|Peptic Ulcer|Bleeding|Proton Pump Inhibitors
Interventions: DRUG: High dose pantoprazole infusion|DRUG: Standard dose pantoprazole infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety Study of GSK1995057 Given as Single and Repeat Intravenous Doses in Healthy Subjects.
Status: COMPLETED
Conditions: Respiratory Disorders
Interventions: DRUG: GSK1995057 single dose|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Gingival Crevicular Fluid Levels of Protein Carbonyl Following the Use of Lycopene in Chronic Periodontitis
Status: COMPLETED
Conditions: Chronic Periodontitis
Interventions: DRUG: Lycopene + SRP|PROCEDURE: SRP only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Active Cycle Breathing Technique (ACBT) on Respiratory Parameters and Pain
Status: NOT_YET_RECRUITING
Conditions: Respiratory Complication|Cardiac Disease
Interventions: PROCEDURE: Active cycle breathing technique|PROCEDURE: Routine care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Different Irrigation System in Retrograde Intrarenal Surgery
Status: COMPLETED
Conditions: Urinary Tract Infections|Ureteric Injury|Sepsis
Interventions: PROCEDURE: Irrigation force
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Adavosertib, Radiation Therapy, and Temozolomide in Treating Patients With Newly Diagnosed or Recurrent Glioblastoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Glioblastoma|Recurrent Glioblastoma
Interventions: DRUG: Adavosertib|RADIATION: Radiation Therapy|DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TMC125-C206: A Phase III Study to Investigate the Efficacy, Tolerability and Safety of TMC125 as Part of an Antiretroviral Regimen, Including TMC114/Ritonavir and an Investigator-selected Optimized Background, in HIV-1 Infected Patients With Limited to no Treatment Options.
Status: COMPLETED
Conditions: HIV
Interventions: DRUG: TMC125|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Adding Ketamine to Levobupivacaine in Paravertebral Block in Thoracotomy
Status: COMPLETED
Conditions: Ketamine|Levobupivacaine|Paravertebral Block|Acute Pain|Chronic Pain
Interventions: DRUG: Ketamine + Levobupivacaine|DRUG: Levobupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Acetylcysteine-containing Triple Therapy in the First Line of Helicobacter Pylori Infection
Status: UNKNOWN
Conditions: Helicobacter Pylori Infection
Interventions: DRUG: N-acetylcysteine + PPI-amoxicillin-clarithromycin|DRUG: PPI-amoxicillin-clarithromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Enteral Versus Intravenous Sedation in Critically Ill High-risk ICU Patients
Status: UNKNOWN
Conditions: Critical Illness|Mechanical Ventilation Complication
Interventions: PROCEDURE: Enteral Sedation (EN)|PROCEDURE: Control group: Intravenous Sedation (IV)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Deep Deltoid Ligament Integrity in Weber B Ankle Fractures - Mini-invasive Arthroscopic Evaluation.
Status: RECRUITING
Conditions: Ankle Fracture - Lateral Malleolus|Deltoid Ligament; Sprain (Strain) (Ankle)|Ankle Fractures
Interventions: DEVICE: Nonoperative treatment|PROCEDURE: Operative treatment|BEHAVIORAL: Standardized education
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation of Modafinil as a Cocaine Treatment Medication and Interactions With Cocaine - 1
Status: UNKNOWN
Conditions: Cocaine-Related Disorders|Drug Administration Schedule|Infusions, Intravenous
Interventions: DRUG: Modafinil
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Botulinum Toxin Type A Haemagglutinin Complex Next Generation (BTX-A-HAC NG) in Glabellar Lines
Status: COMPLETED
Conditions: Glabellar Lines
Interventions: BIOLOGICAL: Botulinum toxin type A|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Comparison of Three Contact Lens Care Systems and Their Effect on Contact Lenses
Status: COMPLETED
Conditions: Contact Lenses
Interventions: DEVICE: Opti-Free RepleniSH multi-purpose disinfecting solution|DEVICE: ReNu MultiPlus multi-purpose solution|DEVICE: Clear Care cleaning and disinfecting system|DEVICE: Senofilcon A contact lens (ACUVUE OASYS)|DEVICE: Lotrafilcon B contact lens (AIR OPTIX AQUA)|DEVICE: Comfilcon A contact lens (Biofinity)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Alcohol, Behavior, and Brain Imaging
Status: COMPLETED
Conditions: Alcohol Drinking|Binge Drinking|Drinking Behavior|Substance-Related Disorders|Ethanol|Physiological Effects of Drugs|Central Nervous System Depressants
Interventions: DRUG: Ethanol|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: International First-in-Human Study of the EnligHTN Generation 2 System in Patients With Drug-resistant Uncontrolled Hypertension
Status: COMPLETED
Conditions: Hypertension|Renal Denervation
Interventions: DEVICE: EnligHTN™ Renal Artery Ablation Catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigation of the Relationship Between Taste Perception and Caries Activity in School Children
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: salty taste perception|OTHER: bitter taste perception|OTHER: sour taste perception|OTHER: sweet taste perception
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: rTMS Treatment of Spasticity in Children With Cerebral Palsy/ Hemiplegia Due to ABI - a RCT
Status: RECRUITING
Conditions: CP (Cerebral Palsy)
Interventions: DEVICE: Repetitive Transcranial Magnetic Stimulation|DEVICE: Sham Repetitive Transcranial Magnetic Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Remegal Fixed Dose as Adjunctive Therapy in Patients With Partial Seizures
Status: COMPLETED
Conditions: Epilepsy|Simple Partial Seizures|Complex Partial Seizures|Partial Seizures With Secondary Generalization
Interventions: DRUG: Remegal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pioglitazone/Glimepiride (Sonias) Combination Tablets Special Drug Use Surveillance Survey in Patients With Type 2 Diabetes Mellitus Who Respond Poorly to Pioglitazone
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: Pioglitazone/glimepiride
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Impact of Methadone on Prolonged Mechanical Ventilation in Patients on Continuous Treatment With Opioids
Status: NOT_YET_RECRUITING
Conditions: Effect of Methadone on the Duration on Mechanical Ventilation
Interventions: DRUG: Methadone group|DRUG: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Pain Education Program Optimization (PEPO) Trial
Status: RECRUITING
Conditions: Chronic Pain|Musculoskeletal Pain
Interventions: BEHAVIORAL: Pain self-management program|BEHAVIORAL: Additional support for self-management program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Saline Lubrication on Post-intubation Complications
Status: COMPLETED
Conditions: Postoperative Sore Throat
Interventions: PROCEDURE: Saline group|PROCEDURE: Dry group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Single Agent Armodafinil for Patient-Reported Fatigue Following Radiation Therapy for Head and Neck Cancer
Status: COMPLETED
Conditions: Head And Neck Cancer|Fatigue
Interventions: DRUG: Armodafinil|OTHER: Placebo|BEHAVIORAL: Questionnaires
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment With Acamprosate in Patients With Schizophrenia and Comorbid Alcoholism
Status: COMPLETED
Conditions: Alcohol Dependence|Schizophrenia
Interventions: DRUG: Acamprosate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of EscharEx to Treat (Debride) Hard to Heal Wounds
Status: COMPLETED
Conditions: Hard to Heal Wounds|Venous Leg Ulcers|Diabetic Lower Extremity Ulcers|Traumatic/ Post Operative Wounds
Interventions: DRUG: EscharEx|DRUG: Gel Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Dose Escalation Study to Assess the Safety, Tolerability, and Pharmacokinetics of ASP4058 Following Single Oral Doses
Status: COMPLETED
Conditions: Pharmacokinetics of ASP4058|Healthy Subjects|Food Effect of ASP4058
Interventions: DRUG: ASP4058|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: A Multi-Center Open-Label Evaluation of the Safety of Sarecycline Tablets in the Treatment of Acne Vulgaris
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: Sarecycline
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Utility, Safety, and Effectiveness of the Bard LifeStent 5F Vascular Stent System
Status: COMPLETED
Conditions: Peripheral Arterial Disease|Intermittent Claudication
Interventions: DEVICE: Bard® LifeStent® 5F Vascular Stent System
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Neoplastic Barrett Esophagus: Endoscopic Piecemeal vs. En Bloc Resection
Status: RECRUITING
Conditions: Barrett Esophagus|Barrett Adenocarcinoma|Esophagus Neoplasm
Interventions: PROCEDURE: Endoscopic mucosal resection|PROCEDURE: Endoscopic submucosal dissection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Hematologic Impact of Umbilical Cord Milking Versus Deferred Cord Clamping in Premature Neonates.
Status: COMPLETED
Conditions: Delayed Cord Clamping|Umbilical Cord Milking|Preterm Neonates
Interventions: PROCEDURE: delayed cord clamping|PROCEDURE: cord milking
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Peer-delivered Brief Motivational Interviewing Via Instant Messaging Interaction in Reducing the Drug Abuse Among Youth
Status: UNKNOWN
Conditions: Drug Abuse|Adolescent Behavior
Interventions: BEHAVIORAL: Brief MI interaction via instant communication|BEHAVIORAL: General health information
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I Clinical Study of SSD8432 in Healthy Adult Subjects
Status: UNKNOWN
Conditions: Healthy Participants
Interventions: DRUG: SSD8432 dose 1~7 and Ritonavir|DRUG: SSD8432 dose 8~9|DRUG: SSD8432 dose 10~12 and ritonavir|DRUG: SSD8432 dose 13 and Ritonavir|DRUG: SSD8432 dose 14 and Ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessing the Effectiveness and Safety of Interferon Bladder Infusion for the Treatment of Interstitial Cystitis
Status: NOT_YET_RECRUITING
Conditions: Interstitial Cystitis
Interventions: DRUG: Interferon|DRUG: Sodium Hyaluronate|DRUG: Sodium Chloride Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: LAMax Vs. Watchman LAAC Device for Subjects With Non-valvular AF to Reduce the Risk of Stroke
Status: COMPLETED
Conditions: Non-valvular Atrial Fibrillation
Interventions: DEVICE: Percutaneous left atrial appendage closure-LAMax|DEVICE: Percutaneous left atrial appendage closure-Watchman
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Tranexamic Acid on Reducing Postoperative Blood Loss in Cervical Laminoplasty
Status: COMPLETED
Conditions: Cervical Myelopathy
Interventions: DRUG: Tranexamic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: RHA® 4 NLF Cannula
Status: COMPLETED
Conditions: Wrinkle|Nasolabial Fold|Aging
Interventions: DEVICE: Split-face injection of RHA® 4 with a cannula into a single NLF.|DEVICE: Split-face injection of RHA® 4 with a needle (TSK 27G x ½") into the contralateral NLF.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Metformin Experience on Minimal Hepatic Encephalopathy
Status: UNKNOWN
Conditions: Liver Cirrhosis|Hepatic Encephalopathy
Interventions: DRUG: Metformin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Radiological Bone Loss on Different Levels of Dental Implants
Status: COMPLETED
Conditions: Alveolar Bone Loss|Peri-Implantitis|Bone Loss in Jaw
Interventions: PROCEDURE: dental implant placement
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Underwater EMR vs. Conventional EMR for Large Non-pedunculated Colonic Polyp
Status: UNKNOWN
Conditions: Colonic Polyp
Interventions: PROCEDURE: Underwater EMR|PROCEDURE: Conventional EMR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Erlotinib and Chemotherapy for 2nd Line Treatment (Tx) of Metastatic Colorectal Cancer (mCRC)
Status: TERMINATED
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: Erlotinib|DRUG: Fluorouracil|DRUG: Leucovorin|DRUG: Oxaliplatin|DRUG: Irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Central Catheters Used for Chemotherapy in Women With Breast Cancer
Status: COMPLETED
Conditions: Catheter Related Complications
Interventions: DRUG: FEC75 (or EC90) x 6|DRUG: FEC100 + Taxotere (EC90 + Taxotere) 3+3|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE