pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Efficacy And Safety Of Bococizumab For Lipid Lowering In Asian Hypercholesterolemia Subjects
Status: WITHDRAWN
Conditions: Primary Hyperlipidemia or Mixed Dyslipidemia
Interventions: BIOLOGICAL: Bococizumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects Of Myofascial Release In Combined With Task-Oriented Circuit Training On Balance And Gait In People With Parkinson's Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Parkinson Disease|Myofascial Release|Exercise Therapy|Movement Disorders
Interventions: OTHER: Myofascial Releasing Group|OTHER: Sham Myofascial Releasing Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Improving Clinician Capacity to Provide Interventions for Manual Wheelchair Users
Status: RECRUITING
Conditions: Paraplegia|Paralysis, Legs
Interventions: OTHER: Part 1 of intervention A - Wheelchair skills training modules|OTHER: Part 2 of intervention A - Asynchronous feedback from a remote trainer|OTHER: Intervention B: Education on wheelchair provision
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Evaluation of Early Bactericidal Activity in Pulmonary Tuberculosis With Clofazimine (C)-TMC207 (J)-PA-824 (Pa)-Pyrazinamide (Z)
Status: COMPLETED
Conditions: Pulmonary Tuberculosis
Interventions: DRUG: TMC207 (J)|DRUG: PA-824 (PA)|DRUG: pyrazinamide (Z)|DRUG: clofazimine (C)|DRUG: Rifafour
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of RAD001 and Erlotinib With Recurrent Head and Neck Squamous Cell Carcinoma
Status: COMPLETED
Conditions: Head And Neck Cancer
Interventions: DRUG: Erlotinib|DRUG: RAD001
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: XL092 (Zanzalintinib) for the Treatment of Patients With Metastatic or Unresectable Leiomyosarcoma
Status: NOT_YET_RECRUITING
Conditions: Metastatic Leiomyosarcoma|Unresectable Leiomyosarcoma
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|PROCEDURE: Echocardiography|PROCEDURE: Multigated Acquisition Scan|DRUG: Zanzalintinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hysteroscopic Tubal Occlusion Using Iso-Amyl 2-Cyano Acrylate (Amcrylate) in Patients With Hydrosalpinx
Status: UNKNOWN
Conditions: Hydrosalpinx|Infertility, Female
Interventions: DRUG: Isoamyl 2-Cyanoacrylate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: 89Zr-bevacizumab PET Scan in Patients With Relapsing Multiple Myeloma
Status: UNKNOWN
Conditions: Multiple Myeloma
Interventions: DRUG: 89Zr-bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Efficacy of Phosphatidylserine-Omega3 in Elderly Subjects With Memory Impairment
Status: COMPLETED
Conditions: Memory Impairment
Interventions: DIETARY_SUPPLEMENT: Phosphatidylserine-Omega3 (SharpPS™-Gold)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Health and Wellness After Preterm Birth
Status: RECRUITING
Conditions: Preterm Birth|Health Care Utilization|Tobacco Use|Contraceptive Usage|Depression|Weight, Birth
Interventions: BEHAVIORAL: Care Coordination after Preterm Birth (CCAPB)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: MPFLR With Fascia Lata Allograft, Based on Isometry Assessment + Elmslie-Trillat TTO
Status: RECRUITING
Conditions: Lateral Patellofemoral Dislocation Closed Traumatic|Lateral Patellar Luxation
Interventions: PROCEDURE: Medial Patellofemoral Ligament Reconstruction (MPFLR) With Fascia Lata Allograft, Based on Isometry Assessment Combined With Elmslie-Trillat Tibial Tuberosity Osteotomy.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of Functional and Morphometric Brain Abnormalities Related to Adolescent Idiopathic Scoliosis (MOR-FO-SIA)
Status: COMPLETED
Conditions: Adolescent Idiopathic Scoliosis
Interventions: DEVICE: MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Chemotherapy, Radiation Therapy, Immunotherapy, and Bone Marrow Transplantation in Treating Patients With Neuroblastoma
Status: COMPLETED
Conditions: Neuroblastoma
Interventions: BIOLOGICAL: filgrastim|BIOLOGICAL: monoclonal antibody 3F8|DRUG: cisplatin|DRUG: cyclophosphamide|DRUG: doxorubicin hydrochloride|DRUG: etoposide|DRUG: mesna|DRUG: perfosfamide|DRUG: vincristine sulfate|PROCEDURE: autologous bone marrow transplantation|PROCEDURE: in vitro-treated bone marrow transplantation|RADIATION: low-LET cobalt-60 gamma ray therapy|RADIATION: low-LET photon therapy|RADIATION: radioisotope therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Creatine, Carnitine and Carnosine in Vegetarians
Status: COMPLETED
Conditions: Dietary Modification
Interventions: BEHAVIORAL: Vegetarian diet|DIETARY_SUPPLEMENT: creatine|DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: Beta-alanine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Cost-Effectiveness of Adding Web-Based Cognitive-Behavioral Therapy (CBT) to Luvox CR for Obsessive Compulsive Disorder (OCD)
Status: UNKNOWN
Conditions: Obsessive Compulsive Disorder
Interventions: DRUG: Luvox CR|BEHAVIORAL: Behavioral Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A RCT on the Preventive Effect of HFNC on Postoperative Pulmonary Complications in Patients With Gynecologic Neoplasms
Status: RECRUITING
Conditions: Gynecologic Surgery|High-flow Nasal Cannula|Post-operative Pulmonary Complications
Interventions: DEVICE: heated humidified high flow nasal cannula oxygen therapy, HFNC|DEVICE: Nasal cannula oxygen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluating Naltrexone for Use in Conjunction With Buprenorphine in Adults With Opioid Use Disorder Transitioning From Buprenorphine Maintenance Prior to First Dose of VIVITROL
Status: COMPLETED
Conditions: Opioid Use Disorder
Interventions: DRUG: Naltrexone|DRUG: Placebo|DRUG: Buprenorphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Extension Study of Protocol DFA102 to Examine the Long-Term Safety, Tolerability, and Effect on Body Weight of Pramlintide Administered in Combination With Metreleptin
Status: COMPLETED
Conditions: Obesity
Interventions: DRUG: Placebo|DRUG: Pramlintide and Metreleptin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Electrical Nerve Block for Amputation Pain
Status: ACTIVE_NOT_RECRUITING
Conditions: Post-Amputation Pain|Phantom Limb Pain|Residual Limb Pain|Stump Pain
Interventions: DEVICE: Altius
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Post-Op Pain Control for Prophylactic Intramedullary Nailing.
Status: RECRUITING
Conditions: Bone Metastases|Lymphoma|Multiple Myeloma|Opioid Use|Pain
Interventions: DRUG: Ketorolac|DRUG: Normal saline|DRUG: Acetaminophen|DRUG: Oxycodone Acetaminophen|DRUG: Morphine|DRUG: Hydrocodone/Acetaminophen|DRUG: Oxycodone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of the Photobiomodulation on the Pelvi-perineal Pain in Immediate Post-partum Situation
Status: COMPLETED
Conditions: Pelvic Pain
Interventions: DEVICE: MILTA Device|DEVICE: " control 1 " fake MILTA device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Salvage Stereotactic Body Radiotherapy of the Prostate Bed for Biochemical Recurrence After Radical Prostatectomy.
Status: NOT_YET_RECRUITING
Conditions: Prostate Cancer
Interventions: RADIATION: stereotactic body radiotherapy|RADIATION: SOC RT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective, Multi-Center Clinical Evaluation of the Open Wedge Osteotomy and Low Profile Plate & Screw (LPS) System Compared to the Proximal Chevron Osteotomy for the Treatment of Hallux Valgus With an Increased Intermetatarsal Angle
Status: COMPLETED
Conditions: Hallux Valgus
Interventions: PROCEDURE: proximal chevron osteotomy|PROCEDURE: proximal open wedge osteotomy with LPS system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Two Different Types of Ankle Foot Orthoses on Gait Outcomes in Patients With Subacute Stroke.
Status: COMPLETED
Conditions: Stroke|CVA|Hemiplegia|Hemiparesis|Foot Drop
Interventions: DEVICE: Posterior Leaf spring AFO|DEVICE: Double adjustable AFO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Ranolazine on Reducing Chest Pain in Patients With Blockage But no Stents
Status: TERMINATED
Conditions: Angina
Interventions: DRUG: Ranolazine|DRUG: Sugar pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The GLOW Study - The YANG System
Status: COMPLETED
Conditions: Diabetes Mellitus|Glucose
Interventions: DEVICE: The YANG SENSOR is an active implantable device, for Real Time Continuous Glucose, Lactate and Ketone Measurement
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Study to Assess Safety and Efficacy of Tenapanor for Treatment of IBS-C in Pediatric Patients 12 to Less Than 18 Years
Status: RECRUITING
Conditions: Irritable Bowel Syndrome With Constipation (IBS-C)
Interventions: DRUG: Tenapanor 50 MG|DRUG: Tenapanor 25 mg bid|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Patients With Non-healing Wounds and Trophic Ulcers Using Autologous Dermal Fibroblasts
Status: COMPLETED
Conditions: Trophic Ulcer|Non-healing Wound|Non-Healing Ulcer of Skin
Interventions: BIOLOGICAL: Dermal fibroblasts|DEVICE: LED phototherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study in Healthy Men to Investigate the Uptake of Buprenorphine and Its Elimination From the Body After Dermal Application as Patches for 96 Hours and for 72 Hours
Status: COMPLETED
Conditions: Pain|Pharmacokinetics
Interventions: DRUG: Transtec 35 µg/hour transdermal patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: VLU Non-Inferiority Study Comparing a Dual Action Pneumatic Compression Device to Multi-Layer Bandaging
Status: TERMINATED
Conditions: Venous Leg Ulcer
Interventions: DEVICE: Dual Action Pneumatic Compression Device|DEVICE: Multi-Layer Bandaging
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Gintuit(TM)for Oral Soft Tissue Regeneration
Status: COMPLETED
Conditions: Gingival Recession
Interventions: DEVICE: Gintuit|OTHER: Autologous palatal tissue
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Adverse Drug Reactions Associated for Oxycodone and Morphine in Postoperative Pain After Abdominal Hysterectomy
Status: UNKNOWN
Conditions: Pain, Postoperative
Interventions: DRUG: Morphine|DRUG: Oxycodone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Contrast-enhanced CT-based Deep Learning Model for Preoperative Prediction of Disease-free Survival (DFS) in Localized Clear Cell Renal Cell Carcinoma (ccRCC)
Status: RECRUITING
Conditions: Clear Cell Renal Cell Carcinoma|Prognostic Cancer Model|Recurrent Renal Cell Cancer
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Percutaneous Autologous Bone-marrow Grafting for Open Tibial Shaft Fracture
Status: COMPLETED
Conditions: Tibial Fractures|Fractures, Open
Interventions: PROCEDURE: Osteosynthesis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testing the Anti-cancer Drug Erdafitinib for Brain Cancers That Have Returned or Progressed Following Treatment
Status: RECRUITING
Conditions: Recurrent Glioblastoma, IDH-Wildtype|Recurrent WHO Grade 2 Glioma|Recurrent WHO Grade 3 Glioma
Interventions: PROCEDURE: Biospecimen Collection|DRUG: Erdafitinib|PROCEDURE: Magnetic Resonance Imaging|PROCEDURE: Optical Coherence Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Connective Tissue Manipulation on General Health and Emotional Status in Women With Primary Dysmenorrhea
Status: COMPLETED
Conditions: Primary Dysmenorrhea
Interventions: OTHER: Connective Tissue Manipulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vorinostat, Azacitidine, and Gemtuzumab Ozogamicin for Older Patients With Relapsed or Refractory AML
Status: COMPLETED
Conditions: Adult Acute Megakaryoblastic Leukemia (M7)|Adult Acute Minimally Differentiated Myeloid Leukemia (M0)|Adult Acute Monoblastic Leukemia (M5a)|Adult Acute Monocytic Leukemia (M5b)|Adult Acute Myeloblastic Leukemia With Maturation (M2)|Adult Acute Myeloblastic Leukemia Without Maturation (M1)|Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities|Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)|Adult Acute Myeloid Leukemia With t(16;16)(p13;q22)|Adult Acute Myeloid Leukemia With t(8;21)(q22;q22)|Adult Acute Myelomonocytic Leukemia (M4)|Adult Erythroleukemia (M6a)|Adult Pure Erythroid Leukemia (M6b)|Recurrent Adult Acute Myeloid Leukemia
Interventions: DRUG: vorinostat|DRUG: gemtuzumab ozogamicin|DRUG: azacitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gadobutrol / Gadavist-enhanced Cardiac Magnetic Resonance Imaging (CMRI) to Detect Coronary Artery Disease (CAD)
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DRUG: Gadobutrol (Gadavist, Gadovist, BAY86-4875)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Ticagrelor With Low-dose Versus Regular Aspirin in Patients With Acute Coronary Syndrome (ACS) at High-Risk for Ischemia After Percutaneous Coronary Intervention
Status: RECRUITING
Conditions: Acute Coronary Syndrome|Interventional Cardiology
Interventions: DRUG: Aspirin|DRUG: Ticagrelor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Of DVS SR In Treatment Of Children And Adolescent Outpatients With MDD
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: Desvenlafaxine Succinate Sustained-Release|DRUG: Desvenlafaxine Succinate Sustained-Release|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Postoperative Rehabilitation Following Trapeziectomy and Ligament Reconstruction Tendon Interposition
Status: COMPLETED
Conditions: Osteoarthrosis of the Carpometacarpal Joint of the Thumb
Interventions: OTHER: casts for the thumb|OTHER: Motion group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Transsphicteric Fistula-in-ano by Method of Laser Thermoobliteration(FiLaC™).
Status: UNKNOWN
Conditions: Anal Fistula
Interventions: PROCEDURE: Fistula-tract laser closure (FiLAC™)|PROCEDURE: Monopolar coagulation of fistulous tract
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of a Questionnaire on Patients' Emergency Room Expectations
Status: COMPLETED
Conditions: Emergencies|Satisfaction, Patient|Expectations|Physician-Patient Relations
Interventions: OTHER: Emergency Department Visit Expectations Questionnaire
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: LB-100 (PP2A Inhibitor) and Atezolizumab (PD-L1 Inhibitor) in Metastatic Colorectal Cancer Patients
Status: RECRUITING
Conditions: Metastatic Microsatellite-stable Colorectal Cancer
Interventions: DRUG: LB-100|DRUG: Atezolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Ketorolac Nasal Spray to Sumatriptan Nasal Spray and Placebo for Acute Treatment of Migraine
Status: COMPLETED
Conditions: Migraines
Interventions: DRUG: Ketorolac|DRUG: Sumatriptan|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of ATx201 as a Topical Antibiotic Agent
Status: COMPLETED
Conditions: Infection, Bacterial
Interventions: DRUG: ATx201 dermal formulations 2%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mothers' Own Milk Optimization for Preterm Infants Project (MoMO PIP) Pilot Study
Status: TERMINATED
Conditions: Vitamin D Deficiency|Nutritional Deficiency
Interventions: DRUG: High dose Cholecalciferol|DRUG: Cholecalciferol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Azithromycin for Severe Acute Malnutrition in CMAM, Nigeria
Status: TERMINATED
Conditions: Severe Acute Malnutrition
Interventions: DRUG: Azithromycin|DRUG: Amoxicillin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Inspiratory Muscle Rehabilitation in Children With Obesity
Status: COMPLETED
Conditions: Pediatric Obesity
Interventions: DEVICE: Pro2 - 75% of participant's MIP|DEVICE: Pro2 - 15% of participant's MIP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Three Regimens of Ketamine Infusion in Complex Regional Pain Syndrome
Status: RECRUITING
Conditions: Ketamine Infusion|Complex Regional Pain Syndromes
Interventions: DRUG: Ketamine|DRUG: Ketamine|DRUG: Ketamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Silicone Hydrogel Lens Wettability With Marketed Lens Care Solutions
Status: COMPLETED
Conditions: Contact Lens Wear
Interventions: DEVICE: Biotrue multipurpose solution|DEVICE: Sauflon Synergi multipurpose solution|DEVICE: OTE Elements multipurpose solution|DEVICE: Silicone hydrogel contact lenses (Acuvue Advance)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: BIO monitorinG in Patients With Preserved Left ventricUlar Function AfteR Diagnosed Myocardial Infarction
Status: COMPLETED
Conditions: Myocardial Infarction|Myocardial Infarction, Acute|Myocardial Infarction Old
Interventions: DEVICE: BioMonitor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Cardiac Autonomic Denervation for Cardio-inhibitory Syncope
Status: NOT_YET_RECRUITING
Conditions: Bradycardia; Syncope|Syncope, Vasovagal
Interventions: PROCEDURE: Electrophysiological study|PROCEDURE: Electrophysiological study and Right side Ganglionated Plexi ablation|PROCEDURE: Electrophysiological study and bi-atrial Ganglionated Plexi ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Comparison Study of PF530 and Betaferon in Healthy Subjects
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DRUG: Interferon beta-1b (PF530, Betaferon)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Osimertinib Plus Dalpiciclib in Patients With EGFR-mutant, CDK4/6 Pathway Aberrant, Advanced Non-small Cell Lung Cancer Following Acquired Resistance to Third-generation EGFR TKI: a Phase II Trial
Status: RECRUITING
Conditions: Non-small Cell Lung Cancer|EGFR Activating Mutation|Cell Cycle Deregulation|EGFR-TKI Resistant Mutation
Interventions: DRUG: Osimertinib plus Dalpiciclib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Efficacy and Safety of SPARC1401 in Acute Low Back Pain
Status: WITHDRAWN
Conditions: Acute Muscle Pain
Interventions: DRUG: SPARC1401-low dose|DRUG: SPARC1401-mid dose|DRUG: SPARC1401-high dose|DRUG: Reference1401 (Tizanidine)|DRUG: Placebo1401
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Candida in the Respiratory Tract Secretions of Critically Ill Patients and The Efficacy of Antifungal Treatment
Status: TERMINATED
Conditions: Ventilator Associated Pneumonia|Respiratory Tract Infection
Interventions: OTHER: Normal Saline|DRUG: anidulafungin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Investigating the Safety, Tolerability, Immunogenicity and Pharmacokinetics of Olamkicept in Healthy Japanese Persons
Status: RECRUITING
Conditions: Gastroenterology
Interventions: DRUG: FE 999301|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: L-Arginine Supplements in Treating Women Who Are Cancer Survivors
Status: COMPLETED
Conditions: Sexual Dysfunction|Sexuality and Reproductive Issues|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DIETARY_SUPPLEMENT: ArginMax|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: MAP Study: Methotrexate and Adalimumab in Psoriasis
Status: COMPLETED
Conditions: Psoriasis
Interventions: BIOLOGICAL: Adalimumab|DRUG: Methotrexate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: EUROpean Intracoronary Cooling Evaluation in Patients With ST-elevation Myocardial Infarction.
Status: UNKNOWN
Conditions: Acute Myocardial Infarction|Reperfusion Injury
Interventions: OTHER: Selective intracoronary hypothermia + PPCI|OTHER: Standard PPCI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pelvic Floor Rehabilitation of Female Pelvic Floor Dysfunction
Status: RECRUITING
Conditions: Pelvic Floor Disorders|Pelvic Organ Prolapse
Interventions: BEHAVIORAL: Pelvic floor muscle training|OTHER: Biofeedback electrical stimulation|OTHER: Magnetic Stimulation|OTHER: Magnetic stimulation combined with biofeedback electrical stimulation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Fluoxetine Essay in Children With Autism
Status: WITHDRAWN
Conditions: Autism
Interventions: DRUG: fluoxetine|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Hemospan® in Prostatectomy Patients
Status: COMPLETED
Conditions: Blood Loss, Surgical|Prostate Cancer|Surgery
Interventions: DRUG: Hemospan (MP4OX)|DRUG: Ringer's lactate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Desoximetasone Spray 0.05%, 0.25%; Dose Ranging Study
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: Desoximetasone 0.05% once daily|DRUG: Desoximetasone 0.05% twice daily|DRUG: Desoximetasone 0.25% once daily|DRUG: Desoximetasone 0.25% once daily|DRUG: Vehicle once daily|DRUG: Vehicle twice daily
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Implementation of an Early Rehabilitation Program for the Patient With Lung Transplantation: From the ICU to Home.
Status: UNKNOWN
Conditions: Lung Transplant|Rehabilitation
Interventions: OTHER: Usual care treatment|OTHER: New Treatment Protocol-MotoMED®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dexmedetomidine Combined With Bupivacaine for Erector Spinae Plane Block
Status: COMPLETED
Conditions: Posterior Lumbosacral Spine Fixation Surgeries
Interventions: DRUG: Dexmedetomidine injection|DRUG: Bupivacaine 0.25% Injectable Solution|DRUG: normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Pilot Study of Bortezomib, Bendamustine and Rituximab on Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Non-Hodgkin's Lymphoma
Interventions: DRUG: bortezomib|DRUG: bendamustine|DRUG: rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Molecular Imaging of the Underlying Mechanism of Cardiotoxicity in Patients With Light Chain Amyloidosis Using PET/CT
Status: RECRUITING
Conditions: Cardiac Amyloidosis
Interventions: DRUG: FNOS|DRUG: Florbetaben
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Biological Therapy in Stage I, Stage II, or Stage III Surgically Resected Pancreatic Cancer
Status: TERMINATED
Conditions: Pancreatic Cancer
Interventions: BIOLOGICAL: carcinoembryonic antigen peptide 1|BIOLOGICAL: hepatitis B antigen peptide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Adjunctive Recombinant Human Interleukin-2 Therapy in Patients With MDR-TB
Status: UNKNOWN
Conditions: MDR TB
Interventions: DRUG: RhIL-2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial to Compare Oxaliplatin, Folinic Acid (FA) and 5-Fluorouracil (5FU) Combination Chemotherapy (FOLFOX-4) With or Without Cetuximab in the 1st Line Treatment of Metastatic Colorectal Cancer (mCRC) in Chinese Rat Sarcoma Viral Oncogene Homolog (RAS) Wild-type Patients
Status: COMPLETED
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: Cetuximab|DRUG: Oxaliplatin|DRUG: Folinic Acid|DRUG: 5Fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Roux-en-Y Gastric Bypass for BMI 27-32 Type 2 Diabetes Versus Best Medical Treatment
Status: COMPLETED
Conditions: Type II Diabetes in Subjects BMI 27 to 32
Interventions: PROCEDURE: Roux-en-Y Gastric Bypass (RYGB)|DRUG: Incretin analogues|DRUG: Xenical|DRUG: SGLT2 inhibitors|DRUG: DPP-4 Inhibitors
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Tarceva for Use in Patients With Relapsed or Refractory Metastatic Non-Small Cell Lung Cancer
Status: TERMINATED
Conditions: NSCLC
Interventions: DRUG: erlotinib and bortezomib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Tolerability of Lubiprostone in Patients With Nonalcoholic Fatty Liver Disease
Status: COMPLETED
Conditions: NAFLD
Interventions: DRUG: Lubiprostone 24Mcg Oral twice daily
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: External Physical Vibration Lithecbole Versus Traditional Row of Stone After Extracorporeal Shockwave Lithotripsy(ESWL)
Status: UNKNOWN
Conditions: Renal Calculi
Interventions: PROCEDURE: extracorporeal shockwave lithotripsy|DEVICE: External Physical Vibration Lithecbole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety, Pharmacokinetics and Pharmacodynamic Characteristics of HHT120 in Healthy Subjects
Status: WITHDRAWN
Conditions: Healthy
Interventions: DRUG: HHT120|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of Tolerability, Safety and Efficacy of Sensory Stimulation at Multiple Dose Levels to Improve Brain Function (Etude Study)
Status: UNKNOWN
Conditions: Alzheimer Disease, Early Onset|Alzheimer Disease|Alzheimer Dementia|Mild Cognitive Impairment|Memory Disorders|Memory Loss|Memory Impairment|Memory Disorders, Age Related|Alzheimer Disease, Late Onset|Cognitive Impairment|Dementia, Mild|Dementia, Alzheimer Type|Cognitive Decline
Interventions: DEVICE: GammaSense Stimulation System (non-invasive, non-significant risk)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: IRENE-G Study: Impact of Resistance Exercise and Nutritional Endorsement on GvHD Symptoms
Status: RECRUITING
Conditions: Graft Vs Host Disease
Interventions: BEHAVIORAL: Supervised resistance training plus nutritional endorsement|BEHAVIORAL: Nutritional endorsement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Prediction of Fetal Lung Maturity
Status: COMPLETED
Conditions: Fetal Distress
Interventions: RADIATION: fetal lung volume|RADIATION: pulmonary artery resistance index|RADIATION: Fetal adrenal gland volume:
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effects of Fenugreek Extract (Fenobet) on Metabolic Syndrome
Status: NOT_YET_RECRUITING
Conditions: Metabolic Syndrome|Complementary Therapies|Diabetes Mellitus, Type 2
Interventions: DIETARY_SUPPLEMENT: Fenobet|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: LBH589 (Panobinostat) for the Treatment of Myelofibrosis
Status: UNKNOWN
Conditions: Primary Myelofibrosis|Polycythemia Vera, Post-Polycythemic Myelofibrosis Phase|Post-Essential Thrombocythemia Related Myelofibrosis
Interventions: DRUG: LBH589
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nicotine Uptake and Abuse Liability Assessments of 5 Blu Disposable Electronic Cigarettes in Comparison to a Combustible Cigarette
Status: ACTIVE_NOT_RECRUITING
Conditions: Healthy Volunteers
Interventions: OTHER: Combustible Cigarette|OTHER: blu Disposable A|OTHER: blu Disposable B|OTHER: blu Disposable C|OTHER: blu Disposable D|OTHER: blu Disposable E
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Randomized Controlled Trial Using Stage-matched Intervention Based on the Transtheoretical Model of Change to Enhance Engaging in Regular Physical Exercise Among High School Female Students.
Status: COMPLETED
Conditions: Physical Exercise
Interventions: BEHAVIORAL: Stage-matched interventions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Propofol Versus Sevoflurane Recovery After Gynecological Surgery
Status: COMPLETED
Conditions: Surgery|Anesthesia
Interventions: DRUG: Sevoflurane|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Multinational Phase II Trial to Compare Safety and Efficacy of SIRT (Y-90 Resin Microspheres) Followed by Atezolizumab Plus Bevacizumab, vs SIRT (SIRT-Y90) Followed by Placebo in Locally Advanced HCC Patients
Status: RECRUITING
Conditions: Locally Advanced Hepatocellular Carcinoma
Interventions: COMBINATION_PRODUCT: SIRT-Y90 with Atezolizumab + Bevacizumab|COMBINATION_PRODUCT: SIRT-Y90 with Placebo (IV)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I/II Study of the Pan-immunotherapy in Patients With Local Advanced/Metastatic BTC
Status: UNKNOWN
Conditions: Biliary Tract Cancer (BTC)
Interventions: DRUG: Manganese Chloride|DRUG: nab-paclitaxel|DRUG: Gemcitabine|DRUG: anti-PD-1 antibody
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I Pilot Study of Biodistribution, Metabolism and Excretion of Novel Radiotracer [18F]Fluorthanatrace (FTT) by PET/CT
Status: RECRUITING
Conditions: Suspected Epithelial Ovarian, Fallopian Tube, or Primary Peritoneal Cancer
Interventions: DRUG: [18F]FluorThanatrace|RADIATION: PET/CT imaging sessions
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multimodal Immune Characterization of RAre Soft Tissue Sarcoma - MIRAS Project From SARRA (SARcome RAre) Project of the French Sarcoma Group
Status: RECRUITING
Conditions: Soft Tissue Sarcoma|Clear Cell Sarcoma|Epithelioid Sarcoma|Perivascular Epithelioid Cell Neoplasms|Desmoplastic Small Round Cell Tumor|Malignant Solitary Fibrous Tumors|Alveolar Soft Part Sarcoma|Epithelioid Hemangioendothelioma|Low Grade Fibromyxoid Sarcoma|Sclerosing Epithelioid Fibrosarcoma
Interventions: OTHER: Patient with Soft Tissue Sarcoma
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Zoledronic Acid Combined Radiotherapy for Bone Metastasis of Non-small Cell Lung Cancer
Status: UNKNOWN
Conditions: Non-small Cell Lung Cancer|Bone Metastasis
Interventions: DRUG: Zoledronic acid|RADIATION: Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Light-emitting-diode in Diabetic Subjects
Status: COMPLETED
Conditions: Diabetic Neuropathies
Interventions: DEVICE: Red Light-emitting diode device|DEVICE: Infrared Light-emitting diode device|DEVICE: Infrared and Red Light-emitting diode device|DEVICE: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mixed Reality and Head-mounted Display for Central Venous Catheterization
Status: RECRUITING
Conditions: Central Venous Catheterization
Interventions: DEVICE: conventional ultrasound|DEVICE: Mixed reality and head-mounted display ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Papaverine on Renal Artery Blood Flow Volume
Status: COMPLETED
Conditions: Kidney Cancer
Interventions: DRUG: Papaverine|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: The Band-Frail Study: A Provincial Intervention to Outweigh Diabetes and Frailty in New Brunswick
Status: COMPLETED
Conditions: Type 2 Diabetes|Frailty
Interventions: BEHAVIORAL: Band-Frail Program
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Açaí Juçara Consumption on Endothelial Function and Arterial Stiffness
Status: UNKNOWN
Conditions: Overweight and Obesity
Interventions: DIETARY_SUPPLEMENT: Hipocaloric Diet with Açaí Juçara|OTHER: Hipocaloric Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of a High-dose Oral Vitamin D3 Bolus on Serum 25(OH)D3 and Vitamin D Receptor Target Gene Expression
Status: COMPLETED
Conditions: Vitamin D Receptor Target Gene Expression|Serum 25(OH)D Concentration
Interventions: DIETARY_SUPPLEMENT: Vitamin D3|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Feasibility of the BrainGate2 Neural Interface System in Persons With Tetraplegia (BG-Tablet-01)
Status: RECRUITING
Conditions: Brainstem Stroke|ALS|Tetraplegia|Spinal Cord Injuries|Cervical Spinal Cord Injury
Interventions: DEVICE: BrainGate Neural Interface System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: A Maastricht Contrast-Induced Nephropathy Guidelines Study: CIN Prevention Guidelines: Appropriate & Cost-effective?
Status: COMPLETED
Conditions: Contrast Induced Nephropathy|Acute Kidney Injury
Interventions: OTHER: No prophylactic iv hydration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of the Contraceptive Efficacy and Safety of a NOMAC-E2 Combined Oral Contraceptive (COC)(P06448)
Status: TERMINATED
Conditions: Contraception
Interventions: DRUG: NOMAC-E2|DRUG: NETA-EE|OTHER: Placebo|DRUG: ethinylestradiol (EE)|DRUG: ferrous fumarate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Clinical Study of Subretinal Transplantation of Human Embryo Stem Cell Derived Retinal Pigment Epitheliums in Treatment of Macular Degeneration Diseases
Status: UNKNOWN
Conditions: Macular Degeneration|Stargardt's Macular Dystrophy
Interventions: PROCEDURE: Subretinal transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Hydrogen Peroxide and Hyaluronic Acid (BMG0703) in the Healing of Post-extraction Sites
Status: UNKNOWN
Conditions: Impacted Third Molar Tooth|Healing Surgical Wounds
Interventions: DRUG: Filming Formulation of Hydrogen Peroxide and Hyaluronic Acid|DRUG: Chlorhexidine mouthwash|OTHER: Placebo product
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing Recipient Site Preparation Using Dermabrasion, Dermaroller and Liquid Nitrogen Induced Blister in Non Cultured Epidermal Cell Suspension in Stable Vitiligo
Status: UNKNOWN
Conditions: Vitiligo
Interventions: PROCEDURE: Dermabrasion with NCES|PROCEDURE: Dermaroller with NCES|PROCEDURE: Liquid nitrogen induced blister with NCES
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase III, Randomized, Double Blind Trial Low Dose Tamoxifen Versus Placebo in Hormone Replacement Therapy (HRT) Users
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Tamoxifen|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Impact of Nocturnal Hypoxemia on Glucose in High Altitude Sleep Disordered Breathing
Status: NOT_YET_RECRUITING
Conditions: Sleep-Disordered Breathing|Glucose Intolerance
Interventions: OTHER: Compressed Air|OTHER: Supplemental Oxygen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of CENV3 Vaccine to Protect Against HCV Infection
Status: UNKNOWN
Conditions: Vaccine Overdose of Undetermined Intent
Interventions: BIOLOGICAL: prophylactic peptide vaccine|BIOLOGICAL: therapeutic peptide vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison Between Laparoscopic Common Bile Duct Exploration and Intraoperative ERCP for Management of Common Bile Duct Stones
Status: COMPLETED
Conditions: Common Bile Duct Gallstones
Interventions: PROCEDURE: laparoscopic common bile duct exploration|PROCEDURE: laparoscopic cholecystectomy and intraoperative endoscopic sphincterotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Sorafenib in Treating Patients With Metastatic Breast Cancer
Status: COMPLETED
Conditions: Male Breast Cancer|Recurrent Breast Cancer|Stage IV Breast Cancer
Interventions: DRUG: sorafenib tosylate|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stellate Ganglion Block in Bulbar Palsy
Status: NOT_YET_RECRUITING
Conditions: Bulbar Palsy
Interventions: BEHAVIORAL: Comprehensive rehabilitation|PROCEDURE: Stellate ganglion block|DRUG: Lidocaine Hydrochloride|BEHAVIORAL: placebo injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized Controlled Trial for Partial Knee Arthroplasty
Status: WITHDRAWN
Conditions: Degenerative Joint Disease of Knee|Osteoarthritis|Traumatic Arthritis|Varus Deformity|Knee Pain Chronic
Interventions: DEVICE: Persona Partial Knee System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety of Buprenorphine Transdermal System (BTDS) in Subjects With Acute Postoperative Pain After Total Knee Replacement
Status: TERMINATED
Conditions: Postoperative Pain
Interventions: DRUG: Buprenorphine transdermal patch|DRUG: Buprenorphine transdermal patch|DRUG: Buprenorphine transdermal patch|DRUG: Placebo BTDS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Rituximab and Belimumab for Lupus Nephritis
Status: COMPLETED
Conditions: Lupus Nephritis
Interventions: BIOLOGICAL: Rituximab|DRUG: Cyclophosphamide|DRUG: Prednisone|DRUG: Methylprednisolone|DRUG: Diphenhydramine|DRUG: Acetaminophen|BIOLOGICAL: Rituximab|DRUG: Cyclophosphamide|DRUG: Prednisone|DRUG: Methylprednisolone|DRUG: Diphenhydramine|DRUG: Acetaminophen|BIOLOGICAL: Belimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness and Safety of Calcium Carbonate in Chronic Kidney Disease With Normophosphatemia
Status: COMPLETED
Conditions: Chronic Kidney Diseases
Interventions: DRUG: Calcium Carbonate|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION