pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Comparative Trial of Valacyclovir Hydrochloride ( 256U87 ) and Acyclovir for the Suppression of Anogenital Herpes Infections in HIV-Infected Patients
Status: COMPLETED
Conditions: Herpes Simplex|HIV Infections
Interventions: DRUG: Valacyclovir hydrochloride|DRUG: Acyclovir
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Decitabine in Treating Patients With Myelofibrosis
Status: ACTIVE_NOT_RECRUITING
Conditions: Primary Myelofibrosis|Secondary Myelofibrosis
Interventions: DRUG: Decitabine|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Vasodilator Response of Inhaled Epoprostenol and Inhaled Nitric Oxide
Status: COMPLETED
Conditions: Pulmonary Hypertension
Interventions: DRUG: Vasodilator testing (Inhaled Nitric Oxide)|DRUG: Vasodilator testing (Inhaled Epoprostenol)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Multiple Ascending Dose Study of MEDI1341 in Patients With Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DRUG: MEDI1341|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Role of Fatty Acids in Vaccine Efficacy
Status: COMPLETED
Conditions: Rabies Vaccination Reaction
Interventions: DIETARY_SUPPLEMENT: Arachidonic acid|DIETARY_SUPPLEMENT: Sunflower oil|BIOLOGICAL: Rabies Vaccine (Vero Cell) for Human Use
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Altis® Single Incision Sling System for Female Stress Urinary Incontinence Study
Status: COMPLETED
Conditions: Stress Urinary Incontinence
Interventions: DEVICE: Altis® Single Incision Sling System (SIS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Efficacy and Safety of Acute Bronchitis Symptoms Improvement for Bronpass Tab. Compared to Erdos Capsule
Status: COMPLETED
Conditions: Acute Bronchitis
Interventions: DRUG: Bronpass Tab.|DRUG: Placebo of Erdos capsule|DRUG: Erdos capsule|DRUG: Placebo of Bronpass Tab.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Cognitive Impairment in Men With Schizophrenia (MK5757-005)(COMPLETED)
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: MK5757|DRUG: Comparator: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I/II Study to Evaluate AZD5851 in GPC3+ Advanced/Recurrent Hepatocellular Carcinoma
Status: RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: BIOLOGICAL: AZD5851
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diagnostic Accuracy of MRI, DWI MRI, FDG-PET/CT and FEC PET/CT in the Detection of Lymph Node Metastases in Surgically Staged Endometrial and Cervical Carcinoma
Status: COMPLETED
Conditions: Surgically Staged Endometrial and Cervical Carcinoma|Cervical Cancer: Invasive Disease, FIGO Stage 1B1 or Higher|Endometrial Cancer|Stage 1A With Myometrial Invasion or Any Higher Stage and Grade 3|Stage 1A With Myometrial Invasion or Any Other Higher Stage and Serous Papillary or Clear Cell Sub-types|Stage II Disease or Above and Any Histology Grade
Interventions: DIAGNOSTIC_TEST: Diffusion-weighted MRI|DIAGNOSTIC_TEST: Fluorodeoxyglucose-18-PET/CT|DIAGNOSTIC_TEST: Fluoro-ethyl-coline-PET/CT
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Tele-detection and Referral Pathways Model for Early Childhood Caries Control
Status: RECRUITING
Conditions: Early Childhood Caries
Interventions: DEVICE: Caries detection method: Intraoral camera|DEVICE: Caries detection method: Smartphone camera|OTHER: Referral pathway: User fee removal|OTHER: Referral pathway: Conventional referral
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: F16IL2 Plus Paclitaxel in Metastatic Merkel Cell Carcinoma
Status: TERMINATED
Conditions: Merkel Cell Carcinoma
Interventions: DRUG: Arm A: F16IL2 in combination with paclitaxel|DRUG: Arm B: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vismodegib in Treating Patients With Recurrent or Refractory Medulloblastoma
Status: COMPLETED
Conditions: Adult Medulloblastoma
Interventions: OTHER: Pharmacological Study|DRUG: Vismodegib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RA-2 13-cis Retinoic Acid (Isotretinoin)
Status: COMPLETED
Conditions: Male Infertility|Klinefelter's Syndrome|Y-chromosome Microdeletions
Interventions: DRUG: 13-cis retinoic acid|DRUG: Calcitriol
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Eshre Study Into The Evaluation of Oocyte Euploidy by Microarray Analysis
Status: COMPLETED
Conditions: Aneuploid Oocytes
Interventions: OTHER: Polar Body Biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Clinical Trial of HuMax-CD4, a New Drug to Treat Advanced Stage T-Cell Lymphoma in the Skin.
Status: COMPLETED
Conditions: Cutaneous T-Cell Lymphoma
Interventions: DRUG: HuMax-CD4|DRUG: HuMax-CD4
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Intrauterine Lidocaine Infusion and Oral Tramadol on Pain During Diagnostic Office Hysteroscopy
Status: COMPLETED
Conditions: Hysteroscopy
Interventions: DRUG: Lidocaine|DRUG: Tramadol|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Influence of Diagnostic Errors on the Prognosis of Acute Pulmonary Embolism
Status: UNKNOWN
Conditions: Pulmonary Embolism|Pulmonary Embolism and Thrombosis|Diagnostic Errors|Embolism|Pulmonary Vascular Disorder
Interventions: OTHER: Diagnostic error
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Reporting Patterns and Results of Initial Antibiotic Treatment in Patients With cUTI, cIAI,NP Including VAP
Status: COMPLETED
Conditions: Urinary Tract Infection (cUTI)|Intra-abdominal Infection (cIAI) and|Nosocomial Pneumonia (NP)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Bone Mineral Density Changes Under Two Tibial Components in Total Knee Arthroplasty
Status: COMPLETED
Conditions: Unilateral Primary Osteoarthritis of Knee
Interventions: DEVICE: Total knee arthroplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Caudal Versus Intravenous Magnesium Sulfate on Emergence Agitation After Sevoflurane In Children.
Status: UNKNOWN
Conditions: Emergence Agitation|Postoperative Pain
Interventions: DRUG: Bupivacaine|DRUG: Magnesium sulfate 50mg|DRUG: Magnesium sulfate 30 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Application of CAD-CAM Technology in Orbital Bone Reconstruction
Status: UNKNOWN
Conditions: Orbital Bone Fracture|Maxillary Cyst|Maxillary Neoplasms|Zygomatic Fractures|Orbital Neoplasms|Facial Deformity
Interventions: PROCEDURE: orbital bone reconstruction with patient specific titanium implant|PROCEDURE: orbital bone reconstruction with preformed titanium plate preoperatively bended on stereolithographic model
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Non-invasive Ventilation by Calibrated Leak in the Treatment of Respiratory Acidosis in ICU
Status: TERMINATED
Conditions: Respiratory Acidosis in ICU Patients
Interventions: PROCEDURE: Non-Invasive Ventilation with Homecare ventilator|PROCEDURE: Non-Invasive Ventilation with ICU ventilator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Contrast Enhanced Ultrasound vs. Computed Tomographic Angiography in the Detection of Endoleaks Following AAA Repair
Status: TERMINATED
Conditions: Endograft Implantation to Repair Abdominal Aortic Aneurysm
Interventions: PROCEDURE: Contrast Enhanced Ultrasound (Contrast Agent: OptisonTM)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Lenalidomide and Vaccine Therapy in Treating Patients With Relapsed or Refractory Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma and Plasma Cell Neoplasm
Interventions: BIOLOGICAL: pneumococcal polyvalent vaccine|DRUG: lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study of Atezolizumab in Combination With Cisplatin + Gemcitabine Before Surgery to Remove the Bladder Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Bladder Cancer|Metastatic Bladder Cancer|Urothelial Carcinoma
Interventions: DRUG: Atezolizumab|DRUG: Gemcitabine|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Milrinone Versus Placebo in Patients With Septic Shock
Status: RECRUITING
Conditions: Septic Shock|Cardiac Output
Interventions: DRUG: Milrinone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Azithromycin in Treating Children With Non Cystic Fibrosis Bronchiectasis
Status: UNKNOWN
Conditions: Non Cystic Fibrosis Bronchiectasis in Children
Interventions: DRUG: Azithromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bedaquiline Roll-out Evidence in Contacts and People Living With HIV to Prevent TB
Status: NOT_YET_RECRUITING
Conditions: Tuberculosis, Latent
Interventions: DRUG: Bedaquiline|COMBINATION_PRODUCT: Isoniazid, rifapentine|DRUG: Levofloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of XB002 in Subjects With Solid Tumors (JEWEL-101)
Status: ACTIVE_NOT_RECRUITING
Conditions: Non Small Cell Lung Cancer|Cervical Cancer|SCCHN|Pancreatic Cancer|Esophageal SCC|Metastatic Castration-resistant Prostate Cancer|Triple Negative Breast Cancer|Hormone Receptor-positive Breast Cancer|Epithelial Ovarian Cancer|Endometrial Cancer|Tissue Factor-Expressing Solid Tumors
Interventions: DRUG: XB002|DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Tiotropium in Patients With COPD and Concomitant Diagnosis of Asthma
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive|Asthma
Interventions: DRUG: Tiotropium inhalation capsules|DRUG: Placebo inhalation capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Effect of Shoulder Traction on Size and Relative Position of Internal Jugular Vein to Carotid Artery
Status: UNKNOWN
Conditions: Internal Jugular Vein Cannulation|Common Carotid Artery|Infants
Interventions: OTHER: caudo-ipsilateral traction of shoulder|OTHER: The ultrasonographic measurements without shoulder traction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Intraoperative EXamination Using MAChine-learning-based HYperspectral for diagNosis & Autonomous Anatomy Assessment
Status: TERMINATED
Conditions: Parathyroid Diseases|Thyroid Diseases|Liver Cancer|Liver Metastases|Digestive Cancer|Digestive Perfusion
Interventions: OTHER: Hyperspectral Imaging
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety Study of Oral Edaravone Administered in Subjects With ALS
Status: TERMINATED
Conditions: ALS
Interventions: DRUG: MT-1186|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fesoterodine Flexible Dose Study
Status: COMPLETED
Conditions: Overactive Bladder
Interventions: DRUG: Fesoterodine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lenalidomide in Treating Patients With Progressive or Recurrent Multiple Myeloma After a Donor Stem Cell Transplant
Status: COMPLETED
Conditions: Refractory Multiple Myeloma|Stage I Multiple Myeloma|Stage II Multiple Myeloma|Stage III Multiple Myeloma
Interventions: DRUG: lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety of Paracetamol as Antipyretic in Treatment of Dengue Infection in Adults
Status: COMPLETED
Conditions: Dengue|Transaminitis
Interventions: DRUG: Paracetamol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Non Invasive Pressure Support Ventilation (NIPPV) Versus Recruitment Maneuver (RM) and Preoxygenation
Status: COMPLETED
Conditions: Obesity
Interventions: PROCEDURE: NIPPV and IRM
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: A Safety and Efficacy Study of Symbicort Turbuhaler Compared With Standard Chronic Obstructive Pulmonary Disease (COPD) Treatment in Japan
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Symbicort Turbuhaler (Budesonide/formoterol)|DRUG: Drug: any available COPD treatment; investigator to decide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Multielectrode Versus Point-by-Point Mapping on Recurrence of Ventricular Tachycardia in Ischemic Heart Disease
Status: SUSPENDED
Conditions: Ventricular Tachycardia
Interventions: DEVICE: Multielecotrde Mapping|DEVICE: Point-by-point mapping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non Invasive Measurements of Intracranial Pressure After Aneurysmal Subarachnoid Hemorrhage
Status: UNKNOWN
Conditions: Aneurysmal Subarachnoid Hemorrhage, Familial
Interventions: DEVICE: Echodia® hand-held equipment (ELIOS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Empirical Steroids and/or Antifungals in Immunocompromised Patients With Acute Respiratory Failure From Undetermined Etiology: a Multicenter Double-blind Randomized Controlled Trial
Status: UNKNOWN
Conditions: Acute Respiratory Failure|Immunocompromised Patients
Interventions: DRUG: Experimental for steroid|DRUG: Experimental for antifungals|DRUG: Experimental for steroids and antifungals|OTHER: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Peer Counseling, Social Engagement, and Combination Interventions in Improving Depressive Symptoms of Filipino Senior Citizens
Status: COMPLETED
Conditions: Depressive Symptoms
Interventions: BEHAVIORAL: Community-based depression interventions
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Association Between Fluid Administration, Oxytocin Administration, and Fetal Heart Rate Changes
Status: TERMINATED
Conditions: Pregnancy|Labor Pain
Interventions: DRUG: Routine oxytocin|DRUG: Half-dose oxytocin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of IMC-1121B (Ramucirumab) With Best Supportive Care in Participants With Gastric Cancer and Adenocarcinoma
Status: COMPLETED
Conditions: Gastric Cancer|Adenocarcinoma
Interventions: BIOLOGICAL: ramucirumab|DRUG: Placebo|OTHER: Best Supportive Care (BSC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Restylane Lidocaine and Restylane Perlane Lidocaine for Facial Augmentation in Asian Population
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DEVICE: Restylane|DEVICE: Perlane
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Safety and Efficacy of TUG (Therapeutic Ultrasound for Glaucoma) in the Treatment of Primary Open Angle Glaucoma or Ocular Hypertension
Status: TERMINATED
Conditions: Glaucoma, Primary Open Angle|Ocular Hypertension
Interventions: DEVICE: TUG|DEVICE: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transvaginal Sacrospinous Hysteropexy Versus Laparoscopic Uterine Lateral Suspension
Status: RECRUITING
Conditions: Pelvic Organ Prolapse|Uterine Prolapse
Interventions: PROCEDURE: Laparoscopic uterine lateral suspension|PROCEDURE: Transvaginal sacrospinous fixation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: PK, Safety, and Tolerability Study of RBP-7000 of Different Molecular Weight Polymer in Subjects With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: RBP-7000
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Role of Fitostimoline Proctogel in Symptoms Relief and Healing in Patients Affected by Anal Fissure
Status: UNKNOWN
Conditions: Fissure in Ano
Interventions: DEVICE: Fitostimoline proctogel|DEVICE: Fitostimoline proctogel + muscle relaxant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Protocoled Quantitative Assessment of Aortic Regurgitation Using Videodensitometry in a Multicontinental Trial in Rotterdam, Montreal, Yamaguchi, Segeberg, Amsterdam.
Status: COMPLETED
Conditions: Aortic Valve Insufficiency|Aortic Valve Regurgitation
Interventions: DIAGNOSTIC_TEST: Standardized protocol for assessing aortic regurgitation using videodensitometry
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: HDL Acute Lipid Optimization in Homozygous Familial Hypercholesterolemia
Status: UNKNOWN
Conditions: Homozygous Familial Hypercholesterolemia|HoFH
Interventions: DEVICE: HDL Therapeutics PDS-2 System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radiosensitization of AVASTIN® (Bevacizumab) With Stereotactic Body Radiotherapy for Colorectal Liver Metastasis
Status: COMPLETED
Conditions: Colorectal Cancer.
Interventions: RADIATION: Stereotactic body radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Open Label Study To Evaluate The Safety and Kinetics of Nelfinavir in Subjects With HIV and Hepatitis C
Status: COMPLETED
Conditions: HIV Infection|Hepatitis C
Interventions: DRUG: nelfinavir 1,250 mg twice daily|DRUG: Zidovudine 300 mg twice daily|DRUG: Lamivudine 150 mg twice daily
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prone Position During ECMO in Pediatric Patients With Severe ARDS
Status: RECRUITING
Conditions: Pediatric Acute Respiratory Distress Syndrome|Extracorporeal Membrane Oxygenation
Interventions: PROCEDURE: prone position
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ivermectin Effect on SARS-CoV-2 Replication in Patients With COVID-19
Status: COMPLETED
Conditions: COVID-19 Drug Treatment
Interventions: DRUG: IVERMECTIN (IVER P®) arm will receive IVM 600 µg / kg once daily plus standard care. CONTROL arm will receive standard care.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Two Prophylactic Antibiotic Protocols in Women With Term Prolonged Pre-labor Rupture of Membrane and Preterm Labor
Status: NOT_YET_RECRUITING
Conditions: Preterm Labor With Preterm Delivery|Premature Rupture of Membranes Prolonged
Interventions: DRUG: Ampicillin Only Product|DRUG: ampicillin plus gentamicin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of Aflibercept And Modified FOLFOX6 As First-Line Treatment In Patients With Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Neoplasms|Neoplasm Metastasis
Interventions: DRUG: aflibercept|DRUG: oxaliplatin|DRUG: 5-FU|DRUG: Folinic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PREVENTion of Clot in Orthopaedic Trauma
Status: COMPLETED
Conditions: Blood Clot|Trauma
Interventions: DRUG: Acetylsalicylic acid|DRUG: Low Molecular Weight Heparin (LMWH)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Guided Written Disclosure Intervention to Promote Post-traumatic Growth in Cancer Patients GUIDED WRITTEN DISCLOSURE
Status: UNKNOWN
Conditions: Breast Cancer|Colorectal Cancer
Interventions: BEHAVIORAL: GWDP|BEHAVIORAL: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Pragmatic Trial to Expand Youth-friendly HIV Self-testing
Status: COMPLETED
Conditions: HIV/AIDS|Sexually Transmitted Infections
Interventions: BEHAVIORAL: Sexual health information|BEHAVIORAL: I-TEST branded HIVST package|OTHER: Follow-up testing and clinic assessments
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Exploring CBTi's Dual Effect on Sleep, Diet, & Chrononutrition
Status: RECRUITING
Conditions: Insomnia
Interventions: BEHAVIORAL: Cognitive Behavioral Therapy for Insomnia (CBT-i)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Bilateral Prefrontal Modulation in Alcoholism
Status: COMPLETED
Conditions: Drug Addiction|Executive Dysfunction
Interventions: DEVICE: transcranial Direct Current Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of IOPI on Swallowing Function and Functional Status in Geriatric Patients
Status: UNKNOWN
Conditions: Dysphagia
Interventions: DEVICE: IOPI Therapy|DEVICE: Tongue Depressor Traditional Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Laser Hair Removal Therapy in HS
Status: NOT_YET_RECRUITING
Conditions: Hidradenitis Suppurativa, Acne Inversa
Interventions: PROCEDURE: Nd:YAG laser hair removal|DRUG: Clindamycin 1 % Topical Lotion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Alignment Efficiency and Coating Durability of Aesthetic Archwires
Status: COMPLETED
Conditions: Tooth Movement
Interventions: OTHER: Aesthetic archwires|OTHER: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Trial: Comparing Buzzy to Intradermal Lidocaine for Peripheral IV Cannulation in Adults
Status: WITHDRAWN
Conditions: Pain, Acute|Patient Satisfaction
Interventions: DRUG: Lidocaine 2% Injectable Solution|DEVICE: Buzzy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: HR20013 for Nausea and Vomiting Associated With Moderate Emetic Risk Anticancer Agents
Status: NOT_YET_RECRUITING
Conditions: Nausea and Vomiting Associated With Moderate Emetic Risk Anticancer Agents
Interventions: DRUG: HR20013 + dexamethasone + palonosetron placebo|DRUG: Palonosetron + dexamethasone + HR20013 placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Tolerability and Efficacy of AM and PM Once Daily Dosing With Extended-release Guanfacine Hydrochloride in Children 6-12 With Attention-Deficit/Hyperactivity Disorder (ADHD) (The ADHD Tempo Study)
Status: COMPLETED
Conditions: Attention-Deficit/Hyperactivity Disorder
Interventions: DRUG: extended-release guanfacine hydrochloride (SPD503)|DRUG: placebo|DRUG: extended-release guanfacine hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Safety, Tolerability and Preliminary Efficacy of Plasma in Improving the Appearance of Onychomycosis
Status: UNKNOWN
Conditions: Onychomycosis
Interventions: DEVICE: MOE Plasma Delivery System A|DEVICE: MOE Plasma Delivery System B
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of LLLT/Music for Smoking Cessation
Status: COMPLETED
Conditions: Nicotine Dependence, Cigarettes
Interventions: DEVICE: Fully Active|DEVICE: LLLT Only|DEVICE: Music Only|DEVICE: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hypofractionated Brain Radiation In EGFR Mutated Adenocarcinoma Cranial Disease (Hybrid)
Status: UNKNOWN
Conditions: Stage IV EGFR Mutated NSCL With Brain Metastases
Interventions: DRUG: Gefitinib 250mg po qd or Tarceva 150mg po qd or Icotinib 125mg po tid Other Name: Gefitinib/Tarceva/Icotinib|RADIATION: WBRT|RADIATION: HFSRS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Emergency Department Initiated Extended-Release Naltrexone and Case Management for the Treatment of Alcohol Use Disorder
Status: TERMINATED
Conditions: Alcohol Use Disorder|Substance Use|Alcohol Abuse or Dependence
Interventions: DRUG: Vivitrol (Extended Release Naltrexone)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of MatPilates in Pain and Functionality in Elderly Woman With Osteoarthritis.
Status: UNKNOWN
Conditions: Osteoarthritis, Knee
Interventions: OTHER: MatPliates|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Diclofenac Administered Before Skull Operations Reduces the Severity of Headache After the Intervention
Status: COMPLETED
Conditions: Postcraniotomy Headache|Intraoperative Analgesic Use|Postoperative Analgesic Use|Postoperative Complications
Interventions: DRUG: Diclofenac|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ICBT (Internet Based Cognitive Behavioral Therapy) for Maternal Depression: Community Implementation in Head Start
Status: RECRUITING
Conditions: Depression
Interventions: BEHAVIORAL: Mom-Net|COMBINATION_PRODUCT: Treatment as Usual/Waitlist
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Pharmacokinetics and Safety Between HCP2303 and Co-administration of Each Component in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: HCP2303|DRUG: RLD2302|DRUG: RLD2102
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cinacalcet to Treat Hypercalcemia in Renal Transplant Recipients
Status: TERMINATED
Conditions: Secondary Hyperparathyroidism|Hypercalcemia
Interventions: DRUG: Cinacalcet HCl
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Pre-operative Educational Pelvic Floor Intervention on Urinary Continence
Status: COMPLETED
Conditions: Prostatectomy|Pelvic Floor Disorders
Interventions: OTHER: Pre operative exercise|OTHER: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effectiveness of Physiotherapist's Communication Skills on Clinical Outcomes in Chronic Musculoskeletal Patients
Status: RECRUITING
Conditions: Chronic Musculoskeletal Pain
Interventions: OTHER: Video about pain neuroscience education with enhancing communication skills|OTHER: Video about pain neuroscience education without enhancing communication skills
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: TheRapeutic Effect of Different immunosuppressAnts on Non-Thymoma Ocular Myasthenia Gravis: a Real-world Study
Status: RECRUITING
Conditions: Ocular Myasthenia Gravis
Interventions: DRUG: Symptomatic Treatment, Steroids, Immunosuppressive Agents( azathioprine, tacrolimus, Mycophenolate Mofetil)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phototherapy in Association to Resistance Training in the Elderly: the Effect on Muscle Strength, Muscle Mass and Functional Capacity
Status: COMPLETED
Conditions: Elderly Men
Interventions: DEVICE: Active Low Level Laser Therapy|BEHAVIORAL: Resistance Training|DEVICE: Placebo Low Level Laser Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of an Integrated Multimodal Lifestyle Intervention for Management of Violence in Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: OTHER: an integrated multimodal lifestyle intervention (MLifeI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparative Effectiveness of Targeted Therapies in BRAF Positive Metastatic Melanoma in the US
Status: COMPLETED
Conditions: Melanoma
Interventions: DRUG: Encorafenib|DRUG: Binimetinib|DRUG: Vemurafenib|DRUG: Cobimetinib|DRUG: Dabrafenib|DRUG: Trametinib
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study Comparative of Formoterol/Fluticasone Foraseq® and Fluticasone in Asthma Patients
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Formoterol/Fluticasone|DRUG: Foraseq®|DRUG: Fluticasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Proof of Mechanism in ELT
Status: COMPLETED
Conditions: Premature Ejaculation
Interventions: DRUG: GSK958108|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pembrolizumab and Chemotherapy Treatment or no Treatment Guided by the Level of TILs in Resected Early-stage TNBC
Status: NOT_YET_RECRUITING
Conditions: Triple-negative Breast Cancer
Interventions: DRUG: Pembrolizumab 25 mg/ml|DRUG: Paclitaxel injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Zimmer Continuum Metal on Polyethylene (MoP) PostMarket Clinical Followup (PMCF) Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Avascular Necrosis|Osteoarthritis|Inflammatory Arthritis|Post-traumatic Arthritis|Rheumatoid Arthritis
Interventions: DEVICE: Continuum Metal on Polyethylene Acetabular System
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Safety Study of LY2811376 Single Doses in Healthy Subjects
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: LY2811376|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Safety of Different Doses of Vaginal Misoprostol Prior to Intra Uterine Contraceptive Device Insertion
Status: COMPLETED
Conditions: Intra-uterine Device Complication
Interventions: DRUG: Misoprostol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Tourniquet on UKA
Status: UNKNOWN
Conditions: Tourniquets|Arthroplasty
Interventions: PROCEDURE: unicondylar knee arthroplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ketamine Infusion as a Method of Cerebral Protection in Children
Status: RECRUITING
Conditions: Brain Injuries
Interventions: DRUG: Ketamine Hcl 50Mg/Ml Inj|DRUG: Ketamine Hcl 50Mg/Ml Inj|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Accelerated Versus Standard CXL in the Treatment of Ectasia Post Refractive Surgery and Penetrating Keratoplasty.
Status: COMPLETED
Conditions: Refractive Surgery
Interventions: DEVICE: Cross linking
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating the Safety and Efficacy of ENV-101 (Taladegib) in Patients With Advanced Solid Tumors Harboring PTCH1 Loss of Function Mutations
Status: ACTIVE_NOT_RECRUITING
Conditions: Solid Tumors With PTCH1 Loss-of-function Mutations
Interventions: DRUG: ENV-101 (taladegib)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate SHR-1210 in Combination With Capecitabine + Oxaliplatin Sequenced by SHR-1210 + Apatinib as First-line Therapy in Treatment of Advanced Gastric Cancer
Status: UNKNOWN
Conditions: Gastric Cancer|GastroEsophageal Cancer
Interventions: DRUG: SHR-1210|DRUG: Capecitabine|DRUG: Oxaliplatin|DRUG: Apatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RBM-007 in Subjects witH ExudatIve Age-related Macular Degeneration
Status: COMPLETED
Conditions: Age-related Macular Degeneration
Interventions: DRUG: RBM-007 Injectable Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oxford Signature vs. Conventional Global Study
Status: TERMINATED
Conditions: Osteoarthritis|Osteoarthritis, Knee|Osteonecrosis
Interventions: DEVICE: Signature Custom Guides|PROCEDURE: Conventional Instrumentation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 1b, Single Center, Clinical Study to Investigate the Safety and Biological Responses to Baminercept in Patients With Chronic HCV Hepatitis.
Status: UNKNOWN
Conditions: Chronic HCV Hepatitis C
Interventions: DRUG: Baminercept
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Biopsychosocial and Conventional Approach in Bladder Pain Syndrome
Status: UNKNOWN
Conditions: Interstitial Cystitis|Bladder Pain Syndrome
Interventions: OTHER: Pain Neuroscience Education|OTHER: Relaxation exercises|OTHER: Cognition target exercise|OTHER: Pelvic floor stretching exercises|DEVICE: Transcutaneous electrical nerve stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Efficacy and Safety of Laparoscopic Intra-abdominal Chemotherapy (PIPAC) Performed in Patients With Peritoneal Carcinomatosis From Colorectal, Ovarian, Gastric Cancer and Primary Peritoneal Tumors
Status: COMPLETED
Conditions: Peritoneal Carcinomatosis
Interventions: DRUG: Pressurized IntraPeritoneal Air-flow Chemotherapy (PIPAC) fixed repeated dose|DRUG: Pressurized IntraPeritoneal Air-flow Chemotherapy (PIPAC) increasing single dose
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Phase II Trial of Pre-Operative Gemcitabine and Nab Paclitacel With or With Out Hydroxychloroquine
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DRUG: gemcitabine|DRUG: abraxane|DRUG: hydroxychloroquine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Brinzolamide/Brimonidine Fixed Combination BID Compared to Brinzolamide BID Plus Brimonidine BID in Subjects With Open-Angle Glaucoma (OAG) or Ocular Hypertension (OHT)
Status: COMPLETED
Conditions: Open-Angle Glaucoma|Ocular Hypertension
Interventions: DRUG: Brinzolamide 10 mg/mL / Brimonidine 2 mg/mL fixed combination eye drops, suspension|DRUG: Brinzolamide 10 mg/mL eye drops, suspension|DRUG: Brimonidine 2 mg/mL eye drops, solution|DRUG: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Does Vaginal Washing Affect the Success Rate of the Labour Induction?
Status: COMPLETED
Conditions: Labor Induction|Dinoprostone Vaginal Insert|Vaginal Infection|Effect Increased
Interventions: PROCEDURE: vaginal lavage group|PROCEDURE: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Transcranial Direct Current Stimulation in Reduction of Pain and Postoperative Opioids Consumption After Spine Surgery
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: DEVICE: tDCS sham motor cortex|DEVICE: active prefrontal cortex stimulation|DEVICE: active motor cortex stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Crossover Study to Compare Pharmacokinetic Property of SYO-1126 and Glivec Film Coated Tab in Healthy Male Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: SYO-1126|DRUG: Glivec film coated tab 4T(400mg)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Assess Effect of Verapamil on Systemic Exposure of EP395 and Effect of EP395 on Systemic Exposure of Midazolam and Digoxin
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease Exacerbation|COPD
Interventions: DRUG: EP395 (Part A and B)|DRUG: Verapamil (Part A)|DRUG: Midazolam (Part B)|DRUG: Digoxin (Part B)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Azidothymidine (AZT) in the Treatment of HIV Infection in Patients Receiving a Bone Marrow Transplant
Status: COMPLETED
Conditions: Lymphoma, Non-Hodgkin|HIV Infections
Interventions: DRUG: Zidovudine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effect of Corticotomy and Low Level Laser Therapy on Orthodontic Tooth Movement
Status: COMPLETED
Conditions: Dental Malocclusion
Interventions: PROCEDURE: Corticotomy and low laser therapy|PROCEDURE: Corticotomy facilitated Orthodontics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Lotrafilcon B Lenses With Different Packaging Solutions
Status: COMPLETED
Conditions: Refractive Error
Interventions: DEVICE: Lotrafilcon B contact lenses with EOBO-41|DEVICE: Lotrafilcon B contact lenses|DEVICE: Hydrogen peroxide-based lens care solution|DEVICE: Saline solution for rinsing contact lenses|DEVICE: Saline solution for rinsing contact lens case
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Comparative Clinical Study of Efficacy and Safety of Remimazolam and Propofol in Patients Undergoing Elective Surgery Under General Anaesthesia
Status: COMPLETED
Conditions: General Anaesthesia
Interventions: DRUG: Remimazolam|DRUG: Propofol|DRUG: Fentanyl|DRUG: Rocuronium bromide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial to Assess the Safety and Immunogenicity of Nanocovax in Heathy Volunteers
Status: UNKNOWN
Conditions: COVID-19
Interventions: BIOLOGICAL: Nanocovax|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Carbon-Ion Radiotherapy Plus Camrelizumab for Locally Recurrent Nasopharyngeal Carcinoma
Status: RECRUITING
Conditions: Nasopharyngeal Carcinoma
Interventions: DRUG: Induction chemotherapy|RADIATION: Carbon-ion radiotherapy|DRUG: Camrelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Renoprotective Effect of Febuxostat on Contrast Induced Acute Kidney Injury in Chronic Kidney Disease Patients Stage 3
Status: COMPLETED
Conditions: Chronic Kidney Disease stage3|Contrast-induced Nephropathy
Interventions: DRUG: Isotonic saline|DRUG: N-acetyl cysteine|DRUG: Febuxostat 80 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Hector-Study to Evaluate the Efficacy of Octreotide in Patients With Inoperable Hepatocellular Carcinoma
Status: COMPLETED
Conditions: Carcinoma, Hepatocellular
Interventions: DRUG: Somatostatin (octreotide)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Ghrelin in Healthy and Frail Older Women
Status: COMPLETED
Conditions: Frailty
Interventions: DRUG: Ghrelin Infusion - Healthy|DRUG: Ghrelin Infusion - Frail|OTHER: Placebo Infusion -Healthy|OTHER: Placebo Infusion - Frail
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Investigating Otilimab in Patients With Severe Pulmonary COVID-19 Related Disease
Status: COMPLETED
Conditions: Severe Acute Respiratory Syndrome
Interventions: BIOLOGICAL: Otilimab|BIOLOGICAL: Placebo 1|BIOLOGICAL: Placebo 2|DRUG: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Aides in Respiration Health Coaching for COPD
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: BEHAVIORAL: Health Coaching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE