pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Comparison of Incisionless Ultrasound Guided Thread Carpal Tunnel Release and Mini Open Carpal in Patients With Bilateral Carpal Tunnel Syndrome
Status: TERMINATED
Conditions: Carpal Tunnel Syndrome Bilateral
Interventions: PROCEDURE: Carpal Tunnel Procedure (open)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Sorafenib or Regorafenib on P63 Expression and Keratinocyte Differentiation in Human Skin
Status: TERMINATED
Conditions: Renal Cell Carcinoma|Hepatocellular Carcinoma|Colorectal Carcinoma
Interventions: PROCEDURE: skin punch biopsy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Diamyd Administered Into Lymph Nodes in Combination With Vitamin D in Type 1 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1|Diabetes Mellitus|Autoimmune Diseases|Metabolic Disease|Glucose Metabolism Disorders|Immune System Diseases|Endocrine System Diseases|Juvenile Diabetes|Insulin Dependent Diabetes|Autoimmune Diabetes|Vitamin D|Physiological Effects of Drugs
Interventions: BIOLOGICAL: Diamyd|DIETARY_SUPPLEMENT: Vitamin D|BIOLOGICAL: Placebo for Diamyd|DIETARY_SUPPLEMENT: Placebo for Vitamin D
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Baclofen Versus Gabapentin in Preventing Postoperative Pain After Laparoscopic Sleeve Gastrectomy
Status: RECRUITING
Conditions: Post Operative Pain
Interventions: DRUG: Baclofen 10mg|DRUG: Gabapentin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: PVB With vs. Without Clonidine for Ventral Hernia Repair
Status: SUSPENDED
Conditions: Ventral Hernia Repair
Interventions: OTHER: Clonidine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Safety and Efficacy of an Inactivated and Non Adjuvanted Vaccine Against Influenza A in Renal Transplant Recipients
Status: COMPLETED
Conditions: Renal Transplant Recipients|Immunosuppression
Interventions: BIOLOGICAL: inactivated non adjuvanted pandemic H1N1 vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Predictive Score for Neonatal Mortality for Women With Premature Rupture of Membranes Between 22 and 28 Weeks of Gestation
Status: UNKNOWN
Conditions: Perinatal Mortality|Premature Rupture of Fetal Membranes
Interventions: OTHER: Validation of a diagnostic test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Aprepitant / Fosaprepitant for the Prevention of Chemotherapy-induced Nausea and Vomiting (CINV) in Colorectal Cancer Patients - SENRI Trial
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: Aprepitant / Fosaprepitant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Ultra-sound for AAA Screening in Smoking Israeli Arab Men
Status: COMPLETED
Conditions: Abdominal Aortic Aneurysm (AAA)
Interventions: OTHER: Duplex ultra sound screening for abdominal aortic aneurysms
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: New Information and Communication Technologies (ICT´s) in Basic Life Support Training for Non-medical Students: Educational Trial
Status: WITHDRAWN
Conditions: Cardiac Arrest, Out-Of-Hospital
Interventions: OTHER: Basic Life Support training based on ICTs|OTHER: Classic Basic Life Support training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Returning to Everyday Tasks Utilizing Rehabilitation Networks-III (RETURN-III)
Status: RECRUITING
Conditions: Cognitive Rehabilitation|ICU Survivorship|Intensive Care Unit|ICU
Interventions: OTHER: Treatment Arm: Computerized Cognitive Rehabilitation|OTHER: Active Control computer games
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess PXL065 in Subjects With Adrenomyeloneuropathy (AMN) Form of X-linked Adrenoleukodystrophy (X-ALD or ALD)
Status: NOT_YET_RECRUITING
Conditions: ALD (Adrenoleukodystrophy)
Interventions: DRUG: PXL065
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lifestyle Intervention Program for Cognitive Impairment
Status: UNKNOWN
Conditions: Mild Cognitive Impairment
Interventions: DIETARY_SUPPLEMENT: BBH-1001 Brain Health Supplement|OTHER: Lifestyle Intervention|DIETARY_SUPPLEMENT: Brain Health Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Intensity-Modulated Radiation Therapy in Treating Younger Patients With Lung Metastases
Status: COMPLETED
Conditions: Adult Rhabdomyosarcoma|Lung Metastases|Metastatic Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor|Previously Treated Childhood Rhabdomyosarcoma|Recurrent Adult Soft Tissue Sarcoma|Recurrent Childhood Rhabdomyosarcoma|Recurrent Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor|Recurrent Wilms Tumor and Other Childhood Kidney Tumors|Stage IV Adult Soft Tissue Sarcoma|Stage IV Wilms Tumor|Stage V Wilms Tumor|Unspecified Adult Solid Tumor, Protocol Specific|Unspecified Childhood Solid Tumor, Protocol Specific
Interventions: RADIATION: intensity-modulated radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High-flow Nasal Oxygenation in Obese Patients During Apnea
Status: COMPLETED
Conditions: Apneic Oxygenation|High-flow Nasal Cannulae|Bariatric Surgery|Anesthesia Induction
Interventions: DEVICE: HFNC|DEVICE: CON (control)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety and Therapeutic Efficacy of Phosphate Enema (Kleen Enema) in Patients Undergoing Sigmoidoscopy
Status: UNKNOWN
Conditions: Irritable Bowel Syndrome
Interventions: DRUG: Phosphate Enema (Kleen® Enema)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Diminishing Accelerated Long-term Forgetting in Mild Cognitive Impairment
Status: RECRUITING
Conditions: Mild Cognitive Impairment|Memory Impairment|Memory Disorders in Old Age
Interventions: DEVICE: NITESGON|DRUG: Lidocaine / Prilocaine Topical Cream|DEVICE: C5/C6 stimulation|DEVICE: Sham NITESGON
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Internet-Based Motivational Interviewing for Colonoscopy
Status: COMPLETED
Conditions: Colorectal Neoplasms
Interventions: BEHAVIORAL: E-Motivate group|BEHAVIORAL: Usual Care Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pharmacokinetics and Acute Effects of Multiple Dose of Nicotine: Electronic Cigarette and Cigarette
Status: COMPLETED
Conditions: Nicotine Use Disorder
Interventions: DRUG: Nicotine|DRUG: Nicotine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Safety and Performance Evaluation of the Topical Hemostatic Device (AC5™) Following Excision of Skin Lesions
Status: COMPLETED
Conditions: Skin Neoplasms
Interventions: DEVICE: AC5 Topical Hemostatic Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Berubicin in Adult Patients With Recurrent Glioblastoma Multiforme (WHO Grade IV)
Status: TERMINATED
Conditions: Recurrent Glioblastoma Multiforme
Interventions: DRUG: Berubicin Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasound-Guided Navigation in Robot-Assisted Laparoscopic Radical Prostatectomy
Status: TERMINATED
Conditions: Prostate Cancer
Interventions: DEVICE: 3-D TRUS navigation software during T-RALP
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hereditary Gastric Cancer Syndromes: An Integrated Genomic and Clinicopathologic Study of the Predisposition to Gastric Cancer
Status: RECRUITING
Conditions: Stomach Neoplasms|Stomach Cancer|Gastric Adenocarcinoma and Proximal Polyposis of the Stomach (GAPPS)|Hereditary Diffuse Gastric Cancer (HDGC)|Familial Diffuse Gastric Cancer
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Trial of Eltrombopag or Intravenous Immune Globulin Before Surgery for Immune Thrombocytopenia Patients
Status: COMPLETED
Conditions: Immune Thrombocytopenic Purpura
Interventions: DRUG: Eltrombopag|DRUG: IVIG infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Electrodermal Activity and Respiration in Patients Treated With Spinal Cord Stimulation
Status: COMPLETED
Conditions: Failed Back Surgery Syndrome
Interventions: OTHER: SCS is switched off|OTHER: SCS is switched on
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Investigation of a Novel Wound Gel to Improve Wound Healing in Chronic Wounds
Status: COMPLETED
Conditions: Wound Infection
Interventions: DRUG: Benzalkonium Gel|OTHER: standard of care topical gel|PROCEDURE: Debridement|DRUG: benzalkonium irrigation|OTHER: Saline Irrigation (SOC Irrigation)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study on the Effect of Renal Function on the Pharmacakokinetics of RO5024048 (Parent of Prodrug RO5024048) Following Multiple Oral Dose Administration of RO5024048
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: RO5024048
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Surgical Implantation of TRAnscatheter vaLve in Native Mitral Annular Calcification (SITRAL) Study
Status: COMPLETED
Conditions: Mitral Annular Calcification
Interventions: DEVICE: Mitral Valve Replacement with Sapien3
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Two Weeks of Voluntary Reduced Physical Activity in Chronic Obstructive Pulmonary Disease (COPD)
Status: UNKNOWN
Conditions: Chronic Obstructive Pulmonary Disease (COPD)|Muscle Atrophy
Interventions: BEHAVIORAL: 14 days of voluntary step count reduction to no more than 1500 steps/day.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Postoperative Pain After Total Laparoscopic Hysterectomy: a Comparison of Single-port and Three-port Laparoscopy
Status: COMPLETED
Conditions: Uterine Disease|Postoperative Pain
Interventions: DEVICE: single-port laparoscopic hysterectomy(single port trochar)|DEVICE: multi-port laparoscopic hysterectomy(multi port trochar)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study With Lido-Patch and Placebo Plaster in Patients Suffering From Postherpetic Neuralgia (PHN)
Status: COMPLETED
Conditions: Post Herpetic Neuralgia
Interventions: DRUG: Lidocaine 5% medicated Plaster|DRUG: Placebo Plaster
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Glycaemic Load and Pre-meal Insulin Doses in Type 1 Diabetes Patients
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: OTHER: Adjustment of pre-prandial insulin doses on the bases of glycaemic load of the meal|OTHER: Adjustment of pre-prandial insulin doses on the bases of carbohydrates content of the meal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Contact Lens Saline Solutions With Scleral GP Contact Lens Wearers Experiencing Fogging
Status: COMPLETED
Conditions: Contact Lens Complication|Debris in Post Lens Tear Reservoir
Interventions: DEVICE: Saline Solution Enriched|DEVICE: Saline Rinse Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Transthecal Metacarpal Block Versus Traditional Digital Block for Painful Finger Procedures in Children
Status: COMPLETED
Conditions: Finger Injuries
Interventions: PROCEDURE: Transthecal Metacarpal Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial Evaluating the Efficacy and Safety of Technosphere® Inhalation Insulin (TI) Inhalation Powder Using the Gen2 Inhaler
Status: TERMINATED
Conditions: Type 2 Diabetes
Interventions: DRUG: Technosphere® Insulin Inhalation Powder|DRUG: Insulin Aspart|DRUG: Insulin Glargine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Levocetirizine Fourfold Dosage in Chronic Spontaneous Urticaria
Status: COMPLETED
Conditions: Chronic Spontaneous Urticaria
Interventions: DRUG: Levocetirizine (as levocetirizine dihydrochloride), 5mg ( then 20 mg) per day . Oral administration.|DRUG: Levocetirizine, (as levocetirizine dihydrochloride) 20 mg ( then 5 mg) per day. Oral administration.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Annual Versus Biannual Infusions of Ocrelizumab in Patients With Active MS,After 2 Years of Initial Treatment, on Freedom From Radiological Disease Activity at Two Years: a Multicenter Randomized Controlled Non-inferiority Trial
Status: RECRUITING
Conditions: Multiple Sclerosis
Interventions: DRUG: Ocrelizumab Injection [Ocrevus]|DRUG: Ocrelizumab Injection [Ocrevus]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Formal Versus Informal Mindfulness Among University Students With and Without Recent Nonsuicidal Self-injury
Status: COMPLETED
Conditions: Nonsuicidal Self-injury|Mindfulness|Stress|Well-Being
Interventions: BEHAVIORAL: Formal mindfulness induction|BEHAVIORAL: Informal mindfulness induction|BEHAVIORAL: Active control task
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Dose Escalation Trial of Traditional Chinese Medicine for Irritable Bowel Syndrome (TCM- IBS)
Status: COMPLETED
Conditions: Irritable Bowel Syndrome
Interventions: DRUG: 20-herb formulation|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prophylactic Antibiotic Treatment During Vaginal Repair
Status: UNKNOWN
Conditions: Uterine Prolapse|Cystocele|Rectocele|Enterocele
Interventions: DRUG: Cefuroxime
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: A Study to Determine the Efficacy and Safety of Luspatercept in Adults With Non Transfusion Dependent Beta (β)-Thalassemia
Status: COMPLETED
Conditions: Thalassemia
Interventions: DRUG: Luspatercept|OTHER: Placebo|OTHER: Best Supportive Care (BSC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Long-Term Safety of Multiple Doses of Tapentadol (CG5503) Prolonged-Release (PR) and Oxycodone Controlled-Release (CR) in Patients With Chronic Pain
Status: COMPLETED
Conditions: Osteoarthritis, Hip|Osteoarthritis, Knee|Lower Back Pain|Pain
Interventions: DRUG: Oxycodone CR|DRUG: Tapentadol (CG5503) ER
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Consolidation Whole Abdominal Intensity-Modulated Radiation Therapy (IMRT) in Advanced Ovarian Cancer
Status: UNKNOWN
Conditions: Ovarian Cancer|Tubal Carcinoma|Primary Peritoneal Carcinoma
Interventions: RADIATION: intensity-modulated whole-abdominal radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Evaluation of Intranasal Use of DSM 32444 Postbiotic in Humans
Status: COMPLETED
Conditions: Rhino Sinusitis
Interventions: DRUG: 0.9% NaCl isotonic saline solution|COMBINATION_PRODUCT: Bacillus subtilis DSM32444, inactivated
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Continuous Epidural Analgesia on Intracranial Pressure by Measuring the Optic Nerve Sheath Diameter Using Ultrasound in Pediatric Patients
Status: UNKNOWN
Conditions: Osteotomy of Lower Extremity
Interventions: PROCEDURE: bolus group and infusion group for epidural block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: LONsurf and G-CSF Use: Being On A Right Dose-intensity to Optimize Treatment Efficacy
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: Trifluridine/Tipiracil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Approach to Continuous Sciatic Nerve Block for Orthopedic Procedures in Day Surgery With Two Different Techniques
Status: COMPLETED
Conditions: Regional Anesthesia Morbidity|Postoperative Pain
Interventions: PROCEDURE: Tibial nerve group|PROCEDURE: Tibial peroneal nerve group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Buprenorphine HCl Buccal Film in the Treatment of Dental Pain
Status: COMPLETED
Conditions: Dental Pain
Interventions: DRUG: Oxycodone|DRUG: Buprenorphine|DRUG: Placebo Film|DRUG: Placebo Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Obstructive Sleep Apnea Master Protocol GPIF: A Study of Tirzepatide (LY3298176) in Participants With Obstructive Sleep Apnea
Status: COMPLETED
Conditions: Sleep Apnea|Obesity
Interventions: DRUG: Tirzepatide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Desloratadine,Phenylephrine Hcl,Ibuprofen Compared to Placebo in Treatment of Symptoms Associated With Common Cold/Flu
Status: SUSPENDED
Conditions: Cold
Interventions: DRUG: Desloratadine+Phenylephrine+Ibuprofen|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Exploratory Study to Assess the Effects of JNJ-39439335 on the Relief of Pain Using a Thermal-Grill Experimental Model
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: JNJ-39439335, Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Lumason® Infusion vs. Bolus Administrations
Status: NOT_YET_RECRUITING
Conditions: Heart Diseases
Interventions: DRUG: Sulfur Hexafluoride Lipid Type A Microspheres 25 MG Injection Powder for Suspension [LUMASON]|DRUG: Lumason
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: REgistry-based Treatment Duration and Mortality in Long-term OXygen Therapy (REDOX)
Status: COMPLETED
Conditions: Chronic Respiratory Failure With Hypoxia
Interventions: DRUG: LTOT 24 h/day|DRUG: LTOT 15h/day
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Effectiveness Analysis of Granulocyte Colony Stimulating Factor Originator Products Versus Biosimilars
Status: COMPLETED
Conditions: Cancer, Breast|Cancer, Lung|Cancer of Colon|Cancer of Pancreas|Cancer, Ovarian|Lymphoma, Non-Hodgkin
Interventions: DRUG: Receipt of granulocyte-colony stimulating factor
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Full-Digital Workflow in Single-Tooth Implant Rehabilitation
Status: COMPLETED
Conditions: Full Digital Workflow|Edentulous Jaw|Implant Site Reaction
Interventions: DEVICE: Full-Digital Workflow in Single-Tooth Implant Rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Effect of Doctor's Biome Medical Food in Individuals With Clostridium Difficile Infection
Status: NOT_YET_RECRUITING
Conditions: Clostridium Difficile Infection
Interventions: DIETARY_SUPPLEMENT: DBMF|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Clinical Trial to Explore the Skin Test Dosage of EEC in People Aged 18 to 65 Years Old and the Safety and Preliminary Efficacy in People Aged 3 to 75 Years Old.
Status: RECRUITING
Conditions: Tuberculosis
Interventions: BIOLOGICAL: 2.5μg/ml EEC|BIOLOGICAL: 5μg/ml EEC|BIOLOGICAL: 5 unit（U） EC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Immunotherapy With Autologous Tumor Lysate-Loaded Dendritic Cells In Patients With Recurrence Of Glioblastoma Multiforme
Status: TERMINATED
Conditions: Glioblastoma
Interventions: BIOLOGICAL: Dendritic Cells Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Efficacy of the Pain Identification and Communication Toolkit
Status: RECRUITING
Conditions: Caregiver Burden|Cognitive Impairment|Dementia|Alzheimer Disease|Pain, Chronic
Interventions: BEHAVIORAL: Pain Identification and Communication Toolkit|BEHAVIORAL: Health Promotion Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Individualized Diagnosis and Treatment of Extraesophageal Reflux in Patients With Chronic Cough
Status: RECRUITING
Conditions: Chronic Cough|Extraesophageal Reflux|Laryngopharyngeal Reflux|Allergy|Asthma
Interventions: BEHAVIORAL: Lifestyle modifications and Antireflux diet|DIAGNOSTIC_TEST: Extraesophageal reflux diagnostic
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CBT4CBT-Buprenorphine + Recovery Coach for Office-based Buprenorphine
Status: UNKNOWN
Conditions: Opioid-use Disorder
Interventions: BEHAVIORAL: CBT4CBT-Buprenorphine + Recovery Coach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial Technology Development for the Validation of Surrogate Prognostic Markers in Patients With Diabetic Nephropathy
Status: UNKNOWN
Conditions: Diabetic Nephropathy
Interventions: DRUG: Calcitriol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SCREENING
Clinical trial: A Long-Term Safety Extension Study of WA19926 in Participants With Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: tocilizumab [RoActemra/Actemra]
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CAD/CAM Angle Fracture Reduction/Plate Guide and Customized 3D Grid Plate Versus Champy's Technique
Status: RECRUITING
Conditions: Mandibular Fractures
Interventions: PROCEDURE: CAD/CAM patient specfifc fracture reduction/plate guide and customized 3D grid plate|PROCEDURE: Champy's techqniue
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Trial of AXS-05 in Patients With Major Depressive Disorder
Status: COMPLETED
Conditions: Depression|Major Depressive Disorder
Interventions: DRUG: AXS-05|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Open-label Extension Trial to Investigate Possible Drug-drug Interactions Between Stiripentol or Valproate and Cannabidiol in Patients With Epilepsy
Status: COMPLETED
Conditions: Epilepsy
Interventions: DRUG: GWP42003-P
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Normobaric Hypoxia and Different Exercise Modes on Blood Glucose Regulation in Overweight Adults
Status: COMPLETED
Conditions: Overweight|Healthy|Physical Inactivity
Interventions: OTHER: Low-moderate intensity exercise|OTHER: Sprint interval training|OTHER: Functional exercise|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Recurrent or Persistent Device Related Thrombus After Left Atrial Appendage Occlusion: The RE-DRT Study
Status: NOT_YET_RECRUITING
Conditions: Percutaneous Left Atrial Appendage Occlusion (LAAO)|Device-related Thrombus (DRT)|Thromboembolic Event|Major Cardioembolic Events|Major Bleeding - TIMI Classification
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Sedentary Behaviors Reduction and Physical Activity Promotion for Optimal Medical StudentS
Status: RECRUITING
Conditions: Health Behavior|Health-Related Behavior|Physical Inactivity|Sedentary Behavior|Sedentary Time
Interventions: BEHAVIORAL: Sedentary and physical activity behaviors
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study Of SU011248 In Combination With Docetaxel In Patients With Advanced Cancer
Status: COMPLETED
Conditions: Advanced Solid Tumors|Non Small Cell Lung Cancer
Interventions: DRUG: sunitinib|DRUG: docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Liposomal Amphotericin B (AmBisome) Pharmacokinetics Given as a Single Intravenous Dose to Obese Patients (ASPEN)
Status: COMPLETED
Conditions: Morbid Obesity
Interventions: DRUG: Administration of study drug
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Biomarkers in Tissue Samples From Patients Who Have Undergone Neck Dissection for Oral Cancer
Status: WITHDRAWN
Conditions: Head and Neck Cancer
Interventions: GENETIC: microarray analysis|GENETIC: allele-specific oligonucleotide real-time quantitative polymerase chain reaction|OTHER: diagnostic laboratory biomarker analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effectiveness of Three Times of Starting Antibiotic Prophylaxis in Patients With Asymptomatic Bacteriuria.
Status: UNKNOWN
Conditions: Asymptomatic Bacteriuria|Antibiotic Prophylaxis
Interventions: PROCEDURE: Prophylactic antibiotic during five days previous to the procedure|PROCEDURE: Prophylactic antibiotic during three days previous to the procedure|PROCEDURE: Only a single dose of Prophylactic antibiotic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Acupressure for Persistent Cancer Related Fatigue
Status: COMPLETED
Conditions: Chronic Fatigue|Breast Cancer|Sleepiness
Interventions: BEHAVIORAL: Relaxation Acupressure|BEHAVIORAL: Stimulating Acupressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: OZONE_EXO: Comparative Analysis of Protocols for Dental Exactions in Patients at Risk of MRONJ: Case-control Study
Status: COMPLETED
Conditions: MEDICATION RELATED OSTEONECROSIS OF THE JAW
Interventions: BIOLOGICAL: OxigenOzone_Insufflation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study to Evaluate the Safety and Efficacy of DR-3001 Versus Placebo in Women With Overactive Bladder
Status: COMPLETED
Conditions: Urinary Incontinence
Interventions: DRUG: DR-3001a|DRUG: DR-3001b|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ixabepilone in Combination With Carboplatin in Patients With Non-small Cell Lung Cancer
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer (NSCLC)
Interventions: DRUG: Ixabepilone, 32 mg/m^2 + Carboplatin, 5 mg/min/mL|DRUG: Ixabepilone, 32 mg/m^2 + Carboplatin, 6 mg/min/mL
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pembrolizumab in Progressive Multifocal Leukoencephalopathy (PML) in Immunocompromised Patients Without HIV Infection
Status: NOT_YET_RECRUITING
Conditions: Progressive Multifocal Leukoencephalopathy
Interventions: DRUG: Pembrolizumab, 25 mg/ml solution for intravenous (IV) injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Yinzhihuang Oral Liquid on Indirect Bilirubin of Neonates With Glucose-6-phosphate Dehydrogenase Deficiency
Status: UNKNOWN
Conditions: Neonatal Hyperbilirubinemia
Interventions: DRUG: Yinzhihuang Oral Liquid
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Refraining From Closed Reduction of Dislocated Distal Radius Fractures in the Emergency Department
Status: RECRUITING
Conditions: Wrist Fractures|Distal Radius Fractures|Closed Reduction of Fracture and Application of Plaster Cast|Wrist Injuries|Radius Fracture Distal
Interventions: PROCEDURE: closed reduction|PROCEDURE: no closed reduction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Hypoparathyroidism With Synthetic Human Parathyroid Hormone 1-34
Status: COMPLETED
Conditions: Hypoparathyroidism
Interventions: DRUG: Synthetic Human Parathyroid Hormone 1-34|DRUG: Calcitriol & Calcium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Examining the Neural Effects of a Behavioral Intervention for Physical Activity in Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: BEHAVIORAL: Behavioral Intervention for Physical Activity in MS (BIPAMS)|BEHAVIORAL: Wellness for MS (WellMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Placebo-Controlled Trial of Safety and Efficacy of Thalidomide in Patients With Infections Due to Mycobacterium and/or HIV
Status: COMPLETED
Conditions: Mycobacterium Avium-Intracellulare Infection|HIV Infections|Tuberculosis, Mycobacterium Infection
Interventions: DRUG: Thalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: Study of ADXS11-001 in Participants With High Risk Locally Advanced Cervical Cancer
Status: TERMINATED
Conditions: High Risk Cervical Cancer|Advanced Cervical Cancer
Interventions: DRUG: ADXS11-001|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Optical Coherence Tomography Drug Eluting Stent Investigation
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DEVICE: JACTAX Drug eluting stent|DEVICE: JACTAX LD drug eluting stent|DEVICE: Taxus Libertè
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Muscle Oxygenation, Type 1 Diabetes, and Glycated Hemoglobin
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: BEHAVIORAL: Incremental maximal exercise|DIETARY_SUPPLEMENT: Oral Glucose Tolerance Test|PROCEDURE: Muscle biopsy|PROCEDURE: Combined DLCO-DLNO|PROCEDURE: Dual energy X-ray absorptiometry|PROCEDURE: Accelerometry over one week|OTHER: Questionnaires
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Brief Problem-solving Intervention in Different Formats for the Prevention of Suicide in Adults Over 50
Status: ACTIVE_NOT_RECRUITING
Conditions: Suicide
Interventions: BEHAVIORAL: Problem-solving-based psychological intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Motorized Fine Needle Biopsy vs Standard Needles
Status: RECRUITING
Conditions: Pancreas Disease|Liver Diseases
Interventions: DEVICE: EUS-guided standard fine needle biopsy|DEVICE: EUS-guided motorized fine needle biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: DIAGNOSTIC
Clinical trial: Compassionate Use of Triheptanoin (C7) for Inherited Disorders of Energy Metabolism
Status: NO_LONGER_AVAILABLE
Conditions: Very Long-chain acylCoA Dehydrogenase (VLCAD) Deficiency|Carnitine Palmitoyltransferase Deficiencies (CPT1, CPT2)|Mitochondrial Trifunctional Protein Deficiency|Long-chain Hydroxyacyl-CoA Dehydrogenase Deficiency|Glycogen Storage Disorders|Pyruvate Carboxylase Deficiency Disease|ACYL-CoA DEHYDROGENASE FAMILY, MEMBER 9, DEFICIENCY of|Barth Syndrome
Interventions: DRUG: triheptanoin
Study Type: EXPANDED_ACCESS
Clinical trial: A Safety and Efficacy Study of the Treatment of Impending and Actual Pathological Fractures in the Humerus From Metastatic Bone Disease
Status: COMPLETED
Conditions: Humerus Pathological Fracture
Interventions: DEVICE: Photodynamic Bone Stabilization System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 10% Carbohydrate Drink for Preventing Post-operative Nausea and Vomiting (PONV) After Spinal Morphine
Status: COMPLETED
Conditions: Nausea and Vomiting, Postoperative
Interventions: DIETARY_SUPPLEMENT: 10% carbohydrate drink
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Clinical Evaluation of Effectiveness and Safety of Dietary Supplement Potensa in Men With Erectile Dysfunction
Status: COMPLETED
Conditions: Erectile Dysfunction
Interventions: DIETARY_SUPPLEMENT: Potensa, a succinate-based dietary supplement|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Hydrolyzed Collagen Peptide Injection for the Treatment of Collateral Ligament Pain
Status: COMPLETED
Conditions: Collateral Ligament Injury of Stifle Joint
Interventions: DEVICE: Arthrys (Collagen Peptide solution)|DRUG: Depo medrol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Investigation of Walking Training With Different Slope Types in COPD Patients
Status: NOT_YET_RECRUITING
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: OTHER: Downhill walking training|OTHER: Level walking training|OTHER: Uphill walking training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Vortioxetine, Paroxetine, and Placebo on Sexual Functioning in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Vortioxetine|DRUG: Paroxetine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized Controlled Trial With Rituximab for Psychotic Disorder in Adults
Status: RECRUITING
Conditions: Schizophrenia Spectrum and Other Psychotic Disorders
Interventions: DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Delgocitinib Cream in Adults With Moderate to Severe Chronic Hand Eczema (DELTA 2)
Status: COMPLETED
Conditions: Chronic Hand Eczema
Interventions: DRUG: Delgocitinib cream|DRUG: Cream vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Anti-Inflammatory Small Drug Adjunctive Therapy for Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus|Insulin Resistance
Interventions: DRUG: Metformin|DRUG: saxagliptin|DRUG: AZD9668|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Double-blind Study to Assess the Efficacy and Safety of Intranasal Esketamine for the Rapid Reduction of the Symptoms of Major Depressive Disorder, Including Suicidal Ideation, in Participants Who Are Assessed to be at Imminent Risk for Suicide
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: Esketamine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Improved Calf Muscle Function on Gait, Balance and Joint Loading in Older Adults
Status: COMPLETED
Conditions: Osteoarthritis, Knee|Mobility Limitation|Accidental Fall
Interventions: OTHER: Gait retraining|OTHER: Gait retraining + strength training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Rate, Rhythm or Risk Control for New-onset Supraventricular Arrhythmia During Septic Shock: a Randomized Controlled Trial
Status: UNKNOWN
Conditions: Supraventricular Arrhythmia|Septic Shock
Interventions: PROCEDURE: Risk control strategy|PROCEDURE: Rate control strategy:|PROCEDURE: Rhythm control strategy:
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Combined Tobacco Treatment in Hospitalized Subjects
Status: RECRUITING
Conditions: Tobacco Smoking|Tobacco Withdrawal|Nicotine Addiction|Nicotine Withdrawal|Nicotine Replacement Therapy
Interventions: DRUG: Bupropion|DRUG: Nicotine replacement therapy (Nicotine patches)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Using CIBPB With or Without IV-PCA After Arthroscopic Rotator Cuff Repair
Status: RECRUITING
Conditions: Analgesia, Patient-Controlled|Brachial Plexus Block|Arthroscopic Rotator Cuff Repair
Interventions: OTHER: CISB with IV PCA group|OTHER: CISB group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Rituximab Plus Lenalidomide for Patients With Relapsed / Refractory Indolent Non-Hodgkin's Lymphoma (Follicular Lymphoma and Marginal Zone Lymphoma)
Status: COMPLETED
Conditions: Lymphoma, Non-Hodgkin
Interventions: DRUG: Rituximab|DRUG: Lenalidomide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immediate Necrosectomy vs. Step-up Approach for Walled-off Necrosis
Status: RECRUITING
Conditions: Pancreatic Fluid Collection|Walled-off Necrosis|Pancreatitis, Acute Necrotizing|Pancreatic Pseudocyst
Interventions: PROCEDURE: Immediate necrosectomy|PROCEDURE: Step-up approach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Angiotensin-Neprilysin Inhibition (ARNI) on Prognosis of Chronic Heart Failure
Status: UNKNOWN
Conditions: Chronic Heart Failure
Interventions: DRUG: Entresto|DRUG: ACEI/ARB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Empowering Primary Care Providers and Patients to Improve Chronic Disease Outcomes: The EMPOWER Participatory Action Research (EMPOWER - PAR)
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus|Hypertension (Without Type 2 Diabetes Mellitus)
Interventions: OTHER: EMPOWER-PAR Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study of the Role of Pomegranate Juice Ellagitannins in the Modulation of Inflammation in Inflammatory Bowel Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Crohn's Disease|Ulcerative Colitis
Interventions: OTHER: 100% pomegranate juice|OTHER: placebo beverage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of the Use of a Single Dose of Erythropoietin to Treat Acute Myocardial Ischemia
Status: COMPLETED
Conditions: CABG|Coronary Artery Disease
Interventions: DRUG: Epoetin alpha|DRUG: NaCl 0.9%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Approaches to Treat Older Adult Women's Urge Incontinence: Pilot Feasibility and Randomized Controlled Trial
Status: COMPLETED
Conditions: Urinary Incontinence, Urge|Urinary Incontinence in Old Age
Interventions: BEHAVIORAL: Mindfulness-Based Stress Reduction|BEHAVIORAL: Health Enhancement Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: The Antiviral Efficacy of Concurrent Zidovudine and 2',3'-Dideoxyinosine or 2',3'-Dideoxycytidine in Patients With Human Immunodeficiency Virus Disease
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Zidovudine|DRUG: Zalcitabine|DRUG: Didanosine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Methotrexate, Trimetrexate Glucuronate, and Leucovorin in Treating Patients With Refractory or Recurrent Osteosarcoma
Status: COMPLETED
Conditions: Sarcoma
Interventions: DRUG: leucovorin calcium|DRUG: methotrexate|DRUG: trimetrexate glucuronate
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Small Step Intervention for Infants With Cerebral Palsy and Other Neurodevelopmental Disorders
Status: COMPLETED
Conditions: Gross Motor Development Delay|Cerebral Palsy
Interventions: BEHAVIORAL: Early intervention for infants|BEHAVIORAL: usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety & Radiation Distribution Study of Cotara® in Patients With Recurrent Glioblastoma Multiforme
Status: COMPLETED
Conditions: Recurrent Glioblastoma Multiforme
Interventions: DRUG: 131-I-chTNT-1/B MAB
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Very Small Embryonic-like Stem Cells for Knee Osteoarthritis
Status: WITHDRAWN
Conditions: Stem Cell Transplant Complications|Knee Osteoarthritis
Interventions: BIOLOGICAL: very small embryonic-like stem cell
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT