pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Study of IMC-A12 Every 2 Weeks in Patients With Tumors Who No Longer Respond to Treatment or No Treatment is Available
Status: COMPLETED
Conditions: Advanced Solid Tumors
Interventions: BIOLOGICAL: IMC-A12|BIOLOGICAL: IMC-A12|BIOLOGICAL: IMC-A12|BIOLOGICAL: IMC-A12|BIOLOGICAL: IMC-A12
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Effects of Remodulin in Patients With Critical Limb Ischemia Following a Vein Bypass Graft
Status: TERMINATED
Conditions: Peripheral Vascular Disease
Interventions: DRUG: Remodulin (treprostinil sodium) Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Study on the Safety and Effectiveness of UCB-NK Cell Infusion in the Treatment of Advanced Gastric Cancer and Gastroesophageal Cancer
Status: UNKNOWN
Conditions: Advanced Gastric Cancer|Gastroesophageal Cancer
Interventions: OTHER: Cell infusion for Dose-finding (Group A)|OTHER: Cell infusion for Extended research (Group B)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fusion of CT Angiography With 3D Contrast Ultrasound as a Method for Follow up for Endovascular Aneurysm Repair
Status: UNKNOWN
Conditions: Abdominal Aortic Aneurysm|Endoleak
Interventions: OTHER: Contrast 3D Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation of an 3D Imaging Intensifier Coupled to a Navigation Station in the Surgery of the Spine and Pelvis
Status: COMPLETED
Conditions: Surgical Procedure, Unspecified
Interventions: DEVICE: Navigation station coupled with a 3D fluoroscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: National Adaptive Trial for PTSD Related Insomnia
Status: RECRUITING
Conditions: Insomnia
Interventions: DRUG: Trazodone|DRUG: Eszopiclone|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Volume Stable Collagen Matrix in Interdental Papilla Reconstruction in Maxillary Esthetic Region
Status: RECRUITING
Conditions: Gingival Recession Localized Moderate
Interventions: PROCEDURE: volume stable collagen matrix|PROCEDURE: subepithelial connective tissue graft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Exploration of the Reward System by Functional MRI in Parkinson's Disease Patients With and Without REM Sleep Behavior Disorder
Status: COMPLETED
Conditions: Parkinson's Disease|REM Sleep Behavior Disorder
Interventions: DEVICE: fMRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Phase 3 Study of Obexelimab in Patients With IgG4-Related Disease
Status: RECRUITING
Conditions: IgG4 Related Disease
Interventions: DRUG: Obexelimab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Automated Fully Closed-Loop Insulin Delivery in Type 1 Diabetes With Ultra-Rapid Lispro (ACOLYTE Study)
Status: RECRUITING
Conditions: Diabetes Mellitus, Type 1
Interventions: DRUG: Lispro|DRUG: Lispro
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Potential of Prebiotic Galacto-oligosaccharides in Improving Efficacy and Safety of Oral Iron Supplementation in HIV-infected Children
Status: UNKNOWN
Conditions: Iron Deficiency|HIV
Interventions: DIETARY_SUPPLEMENT: Galacto-oligosaccharides|OTHER: Maltodextrin|DIETARY_SUPPLEMENT: Ferrous fumarate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Eryaspase in Combination With Chemotherapy Versus Chemotherapy Alone as 2nd-Line Treatment in PAC
Status: COMPLETED
Conditions: Pancreatic Adenocarcinoma
Interventions: DRUG: eryaspase|DRUG: Gemcitabine plus Abraxane|DRUG: Irinotecan plus 5-FU plus leucovorin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Safety and Immune Response to Three Different DNA HIV Vaccines Administered With a MVA-CMDR Boost Vaccine in Healthy, HIV-Uninfected Adults
Status: COMPLETED
Conditions: HIV Infections
Interventions: BIOLOGICAL: DNA Nat-B env|BIOLOGICAL: DNA CON-S env|BIOLOGICAL: DNA Mosaic env|BIOLOGICAL: MVA-CMDR|BIOLOGICAL: Placebo for DNA Nat-B env|BIOLOGICAL: Placebo for DNA CON-S env|BIOLOGICAL: Placebo for DNA Mosaic env|BIOLOGICAL: Placebo for MVA-CMDR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pharmacokinetic Study of Liposomal Vincristine in Patients With Malignant Melanoma & Hepatic Dysfunction
Status: COMPLETED
Conditions: Malignant Melanoma
Interventions: DRUG: Vincristine Sulfate Liposomes Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ritalin: Antiasthenic Effect of Methylphenidate (Ritalin) in Palliative Care in Cancer Patients
Status: TERMINATED
Conditions: Asthenia|Neoplasms
Interventions: DRUG: methylphenidate|DRUG: placebo comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Smoking Treatment and Anxiety Management Program
Status: COMPLETED
Conditions: Nicotine Dependence
Interventions: BEHAVIORAL: Cognitive Behavioral Therapy for smoking cessation|BEHAVIORAL: Cognitive Behavioral Therapy for smoking cessation and anxiety sensitivity reduction.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Can TNF-Alpha Incomplete Secondary Responders Attain a Safe and Efficacious Response Switching to Cimzia
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Cimzia|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Liposomal Bupivacaine in Benign Soft Tissue Tumor Resection
Status: UNKNOWN
Conditions: Benign Neoplasm
Interventions: DRUG: Liposomal bupivacaine|DRUG: Bupivacaine Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Remote Ischemic Conditioning for Acute Ischemic Stroke Treated With Mechanical Thrombectomy（RECAST-MT）
Status: NOT_YET_RECRUITING
Conditions: Acute Ischemic Stroke|Anterior Circulation Brain Infarction
Interventions: DEVICE: 14-day remote ischemic conditioning|DEVICE: 30-day remote ischemic conditioning|PROCEDURE: Endovascular thrombectomy|DRUG: Best medical management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: First-In-Human Study to Evaluate Safety And Pharmacokinetics of Single Escalating Doses of BCD-147 (Bispecific Anti-HER2/HER2 Antibody) in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: BIOLOGICAL: BCD-147
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Number of Remote Limb Ischemic Conditioning Cycles on Learning Enhancement
Status: COMPLETED
Conditions: Healthy, Young Adults
Interventions: BEHAVIORAL: RLIC - 5 cycles|BEHAVIORAL: RLIC - 4 Cycles|BEHAVIORAL: RLIC - 3 Cycles|BEHAVIORAL: Sham conditioning|BEHAVIORAL: Balance training|BEHAVIORAL: Arm training|BEHAVIORAL: Sequence production training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Nintedanib in Molecularly Selected Patients With Advanced Non-Small Cell Lung Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Carcinoma, Non-Small-Cell Lung|Non-Small Cell Lung Cancer|Nonsmall Cell Lung Cancer
Interventions: DRUG: Nintedanib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Role of Circadian Rhythm in the Effect of Sleep Intervention on Obesity Prevention in Early Childhood
Status: NOT_YET_RECRUITING
Conditions: Infant Sleep Problem
Interventions: BEHAVIORAL: Behavioral sleep intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Perioperative Diaphragmatic Ultrasound as Predictive Index of Atelectasis in Bariatric Surgery
Status: UNKNOWN
Conditions: Postoperative Pulmonary Atelectasis|Morbid Obesity
Interventions: DEVICE: Diaphragmatic Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Free Fatty Acids, Body Weight, and Growth Hormones Secretion in Children
Status: TERMINATED
Conditions: Obesity|Short Stature|Growth Hormone Deficiency
Interventions: DRUG: Niacin First|DRUG: Placebo First|DRUG: Dose-Establishing Study 1 Niacin 250mg|DRUG: Dose-Establishing Study 1 Niacin 500mg|DRUG: Dose-Establishing Study 2 Niacin 500mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Study to Test the Safety and Tolerability of PF-07062119 in Patients With Selected Advanced or Metastatic Gastrointestinal Tumors.
Status: TERMINATED
Conditions: Gastrointestinal Tumors|Colorectal Adenocarcinomas|Gastric Adenocarcinomas|Esophageal Adenocarcinomas
Interventions: DRUG: PF-07062119|DRUG: Anti-PD1|DRUG: Anti-VEGF
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Caregiver-mediated Intervention Improves the Functional Ability of Home-living Chronic Stroke Patients
Status: COMPLETED
Conditions: Stroke
Interventions: OTHER: Care-giver mediated training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: VR&R: Providing Caregiver Respite by Managing BPSDs and Improving QoL in People With Dementia Using Immersive VR-Therapy
Status: NOT_YET_RECRUITING
Conditions: Dementia
Interventions: BEHAVIORAL: Immersive VR Therapy in Head-Mounted Device (HMD)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: VIT-ARMin Virtual, Intensified and Patient-tailored Robotic Arm Therapy With the Exoskeleton Robot ARMin
Status: TERMINATED
Conditions: Stroke|Spinal Cord Injury|Healthy
Interventions: DEVICE: ARMin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Auricular Transcutaneous Electrical Nerve Stimulation Treatment of Autism
Status: UNKNOWN
Conditions: Autism Spectrum Disorder
Interventions: OTHER: 1 Hz Auricular transcutaneous electrical nerve stimulation|OTHER: 20 Hz Auricular transcutaneous electrical nerve stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Aprepitant/MK0869 for Prevention of Chemotherapy Induced Nausea and Vomiting Associated With Cisplatin (0869-169)(COMPLETED)
Status: COMPLETED
Conditions: Chemotherapy-induced Nausea and Vomiting (CINV)
Interventions: DRUG: aprepitant|DRUG: Comparator: Placebo to aprepitant|DRUG: dexamethasone|DRUG: granisetron|DRUG: dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: How Side Effects of Avonex Are Affected by Gradually Increasing to Full Dose vs Starting at Full Dose
Status: TERMINATED
Conditions: Relapsing Remitting Multiple Sclerosis
Interventions: DRUG: Interferon beta-1a
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Maternal Nutrition Interventions in Uttar Pradesh, India
Status: COMPLETED
Conditions: Anemia|Undernutrition|Underweight|Stunting|Maternal Malnutrition
Interventions: BEHAVIORAL: Maternal Nutrition Behavior change
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Interpretation Modification Program for Social Phobia
Status: COMPLETED
Conditions: Social Anxiety Disorder|Social Phobia
Interventions: BEHAVIORAL: Interpretation Modification Program|BEHAVIORAL: Interpretation Control Condition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Wound Dressings for Hidradenitis Suppurativa
Status: COMPLETED
Conditions: Hidradenitis Suppurativa
Interventions: DEVICE: Cutimed Sorbact Hydroactive B wound dressing|DEVICE: Cutimed Siltect wound dressing|DEVICE: Sorbion Sana multi-star wound dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: mTLIP vs. ITP Blocks in Lumbar Disc Surgery
Status: ACTIVE_NOT_RECRUITING
Conditions: Lumbar Disc Herniation|Pain, Postoperative|Regional Aneshesia
Interventions: PROCEDURE: modified thoracolumbar interfacial plan block (mTLIP)|PROCEDURE: Intertransverse process block (ITP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of PH3 in Diabetic Nephropathy
Status: COMPLETED
Conditions: Diabetic Nephropathy
Interventions: DRUG: PH3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Empagliflozin and Cardiac Remodelling in People Without Diabetes
Status: COMPLETED
Conditions: Cardiovascular Diseases|Left Ventricular Hypertrophy
Interventions: DRUG: Empagliflozin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Outpatient Management of Preterm Prelabor Rupture of Membranes
Status: COMPLETED
Conditions: Management of Preterm Prelabor Rupture of Membranes
Interventions: OTHER: Outpatient management of preterm prelabor rupture of membranes|OTHER: Inpatient management of preterm prelabor rupture of membranes
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Necessity of Anti-inflammatory Drops After Laser Peripheral Iridotomy
Status: UNKNOWN
Conditions: Glaucoma, Closed-Angle|Glaucoma, Narrow-Angle|Glaucoma, Angle-Closure
Interventions: DRUG: Dexamethasone Disodium Phosphate 0.1%|DRUG: Nepafenac 0.1%|DRUG: Hydroxyethylcellulose 0.19%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Tanzânia Association in the Treatment of Erectile Dysfunction Associated With Benign Prostatic Hyperplasia
Status: UNKNOWN
Conditions: Erectile Dysfunction|Benign Prostatic Hyperplasia
Interventions: DRUG: Tanzânia association|DRUG: Omnic Ocas|OTHER: Omnic Ocas placebo|OTHER: Tanzânia association placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Determining a Viral Load Threshold for Treating Cytomegalovirus (CMV)
Status: COMPLETED
Conditions: Viraemia
Interventions: DRUG: ganciclovir (start when CMV PCR >200copies / ml x2)|OTHER: Monitor (Treatment starts when CMV PCR >3,000 copies / ml)|DRUG: Stop treatment when 2 levels CMV PCR <3,000 copies / ml|OTHER: Monitor (Treatment stops CMV PCR <200 copies / ml x2)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessing the Tolerance and Clinical Benefit of feCAl tranSplantation in patientS With melanOma
Status: RECRUITING
Conditions: Melanoma
Interventions: DRUG: MaaT013|DRUG: Ipilimumab|DRUG: Nivolumab|DRUG: MoviPrep|DRUG: Normacol|DRUG: Placebo of Maat013
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Paclitaxel-Coated Balloons Against Drug-Eluting Bioresorbable Scaffolds for Elective PCI Using OCT
Status: TERMINATED
Conditions: Coronary Artery Disease
Interventions: DEVICE: OCT-guided BRS implantation|DEVICE: FFR-guided DCB-only PCI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Can Virtual Reality Improve the Progressive Muscular Relaxation Technique Efficacy?
Status: COMPLETED
Conditions: Anxiety|Coping Skills|Depression|Stress, Emotional|Quality of Life
Interventions: COMBINATION_PRODUCT: Progressive Muscular Relaxation via Zoom, and Exposure to a Virtual Reality scenarios deployed by an Head mounted tool (Oculus Quest 2).|COMBINATION_PRODUCT: Progressive Muscular Relaxation via Audio-track, and Exposure to a Virtual Reality scenarios deployed by an Head mounted tool (Oculus Quest 2).|BEHAVIORAL: Progressive Muscular Relaxation via Zoom, and Exposure to a Guided Imagery Exposure.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Alterations of Gut Microbiome, Function, and Its Intervention After Defunctioning Ileostomy
Status: RECRUITING
Conditions: Ileostomy - Stoma|Rectal Cancer|Microbial Disease|Intestinal Functional Disorder
Interventions: DRUG: MIYAIRI 588
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Effects of Costophrenic Assisted Cough and Anterior Chest Compression Technique in COPD Patients
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: OTHER: Costophrenic assisted cough|OTHER: Anterior chest compression
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Baden Prevention and Reduction of Incidence of Postoperative Delirium Trial
Status: COMPLETED
Conditions: Postoperative Delirium
Interventions: DRUG: Haloperidol|DRUG: Ketamine|DRUG: Haloperidol + Ketamine|DRUG: Saline solution (NaCl 0.9%)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Peginterferon α-2b as a Maintenance Therapy in Participants With Multiple Myeloma Who Responded to Induction Therapy (P01972-AM7)
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Peginterferon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Efficacy and Safety of NBI-1065845 in Adults With Major Depressive Disorder (MDD)
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: Placebo|DRUG: NBI-1065845
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Saxagliptin Treatment in Subjects With Type 2 Diabetes Who Are Not Controlled With Diet and Exercise
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Saxagliptin|DRUG: Saxagliptin|DRUG: Saxagliptin|DRUG: Placebo matching Saxagliptin|DRUG: Metformin|DRUG: Placebo matching Metformin|DRUG: Saxagliptin|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of the Axone Micro Quadripolar Lead for Enhanced Cardiac Resynchronization Therapy
Status: ACTIVE_NOT_RECRUITING
Conditions: Heart Failure|Cardiac Resynchronization Therapy
Interventions: DEVICE: Implantation of the Axone 4LV Lead
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Ispinesib in Metastatic Breast Cancer
Status: TERMINATED
Conditions: Breast Neoplasms
Interventions: DRUG: Ispinesib|DRUG: Ispinesib|DRUG: Ispinesib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vaccine Therapy for Patients With Stage IIIC-IV Ovarian Epithelial, Fallopian Tube, or Primary Peritoneal Cavity Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Fallopian Tube Clear Cell Adenocarcinoma|Fallopian Tube Endometrioid Tumor|Fallopian Tube Mucinous Neoplasm|Fallopian Tube Serous Neoplasm|Fallopian Tube Transitional Cell Carcinoma|Ovarian Clear Cell Cystadenocarcinoma|Ovarian Endometrioid Adenocarcinoma|Ovarian Mucinous Cystadenocarcinoma|Ovarian Seromucinous Carcinoma|Ovarian Serous Cystadenocarcinoma|Ovarian Transitional Cell Carcinoma|Primary Peritoneal Serous Adenocarcinoma|Recurrent Fallopian Tube Carcinoma|Recurrent Ovarian Carcinoma|Recurrent Primary Peritoneal Carcinoma|Stage IIIC Fallopian Tube Cancer|Stage IIIC Ovarian Cancer|Stage IIIC Primary Peritoneal Cancer|Stage IV Fallopian Tube Cancer|Stage IV Ovarian Cancer|Stage IV Primary Peritoneal Cancer|Undifferentiated Fallopian Tube Carcinoma|Undifferentiated Ovarian Carcinoma
Interventions: OTHER: Laboratory Biomarker Analysis|BIOLOGICAL: Multi-epitope Folate Receptor Alpha-loaded Dendritic Cell Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Efficacy of the décoLITE LED Device in Treating the Signs of Skin Aging of the décolletage Area
Status: COMPLETED
Conditions: Wrinkle
Interventions: DEVICE: decoLITE (TN2037)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Enhancing Anti--Tetanus Vaccine Response After Autologous Stem Cell Transplantation
Status: TERMINATED
Conditions: Plasma Cell Myeloma
Interventions: DRUG: Melphalan|PROCEDURE: Peripheral Blood Stem Cell Transplantation--CD34 HSCT|PROCEDURE: Peripheral Blood Stem Cell Transplantation--AHSCT|BIOLOGICAL: T Cell-Depleted Hematopoietic Stem Cell Transplantation|BIOLOGICAL: Tetanus Toxoid Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Safety and Efficacy of a Probiotic Intervention on SIBO and Related Gastrointestinal Symptoms
Status: RECRUITING
Conditions: Small Intestinal Bacterial Overgrowth|SIBO
Interventions: DIETARY_SUPPLEMENT: Probiotic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Postmenopausal Women Estrogen and Progesterone Infusion
Status: COMPLETED
Conditions: Postmenopause|Aging
Interventions: DRUG: Estradiol infusion|DRUG: Progesterone infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The STRENGTH Study: Shapely Sisters Targeting Realistic Exercise and Nutrition Goals Through Healthy Habits
Status: COMPLETED
Conditions: Obesity
Interventions: BEHAVIORAL: Standard Weight Loss Intervention|BEHAVIORAL: Stress-Focused Weight Loss Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Quality of Life After Biliodigestive Anastomosis (BDA) or Stents to Treat Biliary Obstruction in Pancreas Cancer
Status: TERMINATED
Conditions: Local Tumor Spread|Advanced Cancer|Metastasized|Pancreatic Cancer Non-resectable|Jaundice
Interventions: PROCEDURE: Stent|PROCEDURE: Biliodigestive anastomosis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Measuring Cell-Free DNA (cfDNA) Levels in People With Follicular Lymphoma
Status: RECRUITING
Conditions: Follicular Lymphoma
Interventions: DIAGNOSTIC_TEST: cfDNA testing|OTHER: sample of saliva or fingernail clipping|DIAGNOSTIC_TEST: pre-treatment test specimen|DIAGNOSTIC_TEST: PET/CT, CT, or MRI testing
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: SEMPERFLO* Pain Management System in Inguinal Hernia Repair
Status: TERMINATED
Conditions: Inguinal Hernia|Pain
Interventions: DEVICE: SEMPERFLO Pain Management System|DEVICE: ON-Q PainBuster Post-Op Pain Relief System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Lyra Gait Training on the Mobility of Geriatric Rehabilitation Inpatients
Status: TERMINATED
Conditions: Mobility Limitation|Muscle Weakness
Interventions: OTHER: Gait training with the THERA-Trainer Lyra|OTHER: Physical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PF-07304814 for Inpatients With COVID-19 (An ACTIV-3/TICO Treatment Trial)
Status: TERMINATED
Conditions: COVID-19
Interventions: DRUG: PF-07304814|DRUG: Placebo|BIOLOGICAL: Remdesivir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Single-Center Evaluation of the Relative Efficacy of EM-100 Compared to Zaditor® (Ketotifen Fumarate Ophthalmic Solution 0.035%) and Vehicle
Status: COMPLETED
Conditions: Allergic Conjunctivitis
Interventions: DRUG: EM-100|DRUG: Zaditor®|DRUG: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1/2 Study of CS7017, an Oral PPARγ Agonist, in Combination With Paclitaxel
Status: TERMINATED
Conditions: Anaplastic Thyroid Cancer
Interventions: DRUG: CS-7017|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of PF-06412562 on Value-based Decision-making in Healthy Individuals
Status: COMPLETED
Conditions: Decision Making
Interventions: DRUG: PF-06412562|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Multiple Dose Study of AVD-104 for Geographic Atrophy (GA) Secondary to Age-Related Macular Degeneration (AMD)
Status: RECRUITING
Conditions: Geographic Atrophy of the Macula|Macular Degeneration
Interventions: DRUG: AVD-104|DRUG: Avacincaptad
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate CORT125281 in Combination With Enzalutamide in Patients With mCRPC
Status: COMPLETED
Conditions: Metastatic Castration-Resistant Prostate Cancer
Interventions: DRUG: CORT125281|DRUG: Enzalutamide (Xtandi)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Safety and Efficacy of Bone Marrow Derived Autologous Cells for the Treatment of Diabetes Mellitus.
Status: UNKNOWN
Conditions: Diabetes Mellitus.
Interventions: OTHER: Intra thecal transplantation of autologous MNC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Population Pharmacokinetic (PK) Study of Zinforo (Ceftaroline) in Critical Care Patients With Early-onset Pneumonia and Normal or Augmented Renal Clearance
Status: COMPLETED
Conditions: Pneumonia
Interventions: DRUG: Ceftaroline
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study in Healthy Male Subjects to Evaluate the Effect of Itraconazole and Rifampicin on the PK of Fedovapagon
Status: COMPLETED
Conditions: Nocturia
Interventions: DRUG: fedovapagon|DRUG: Itraconazole|DRUG: rifampicin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Investigational Immuno-therapy Study of Experimental Medication BMS-986179 Given Alone and in Combination With Nivolumab
Status: COMPLETED
Conditions: Malignant Solid Tumor
Interventions: BIOLOGICAL: BMS-986179|BIOLOGICAL: Nivolumab|BIOLOGICAL: rHuPH20
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of tDCS Combined With VR on Anxious Ruminations in Healthy Subjects With a Vulnerability to Rumination
Status: COMPLETED
Conditions: Rumination
Interventions: DEVICE: VR + active brain stimulation|DEVICE: VR +sham brain stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Impact of Cannabis Oil on Nutrition in Hemodialysis Patients Study (ICON-HP Study)
Status: WITHDRAWN
Conditions: Protein-Energy Malnutrition|Hemodialysis|Appetite Disorders
Interventions: DRUG: Cannabis oil|DRUG: Placebo/ Regular Oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of RP2 Monotherapy and RP2 in Combination With Nivolumab in Patients With Solid Tumors
Status: RECRUITING
Conditions: Cancer
Interventions: BIOLOGICAL: RP2|BIOLOGICAL: nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Caldine® on Renal Function in Balanced Hypertension
Status: TERMINATED
Conditions: Hypertension
Interventions: DRUG: Lacidipine|DRUG: Diuretics|DRUG: antihypertensive drugs|DRUG: alpha blockers|DRUG: Angiotensin-Converting Enzyme Inhibitors|DRUG: beta blockers
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effectivity of Postpartum Dexamethasone for Women With Class I HELLP Syndrome
Status: TERMINATED
Conditions: HELLP Syndrome
Interventions: DRUG: dexamethasone|DRUG: Placebo|DRUG: dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Calcium Hydroxide, Mineral Trioxide Aggregate and Biodentine (Trademark) as Direct Pulp Capping of Permanent Teeth
Status: COMPLETED
Conditions: Caries|Dental Pulp Exposure
Interventions: DRUG: Mineral trioxide aggregate|DRUG: Calcium hydroxide|DRUG: Biodentine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison Study of Different Tumor Biopsy Method for Sentinel Lymph Node Biopsy in Breast Cancer
Status: UNKNOWN
Conditions: Breast Cancer|Sentinel Lymph Node
Interventions: BEHAVIORAL: Vacuum-Assisted Biopsy|BEHAVIORAL: Core Needle Biopsy|BEHAVIORAL: Intraoperative Excisional Biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A 2-Part First-in-Human Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Immunogenicity of CMTX-101
Status: RECRUITING
Conditions: Community-acquired Pneumonia|Bacterial Pneumonia
Interventions: DRUG: CMTX-101|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Safety, Tolerability, and Pharmacokinetics of GAP-134 Administered Intravenously
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: GAP-134|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic and Pharmacodynamic Profiles of Aliskiren in Japanese Patients With Mild to Moderate Essential Hypertension
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: SPP100 (aliskiren)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Nivolumab in Preventing Colon Adenomas in Participants With Lynch Syndrome and a History of Partial Colectomy
Status: TERMINATED
Conditions: Colon Adenoma|Colon Carcinoma|Lynch Syndrome|MLH1 Gene Mutation|MSH2 Gene Mutation
Interventions: BIOLOGICAL: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Epidural Steroid Following Discectomy for Herniated Disc Reduces Morbidity
Status: COMPLETED
Conditions: Disc Disease
Interventions: DRUG: Methylprednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Peginterferon and Ribavirin, With or Without Telaprevir, for Genotype 1 Hepatitis C and IL28B CC Polymorphism
Status: WITHDRAWN
Conditions: Hepatitis C
Interventions: DRUG: Peginterferon alfa-2a|DRUG: Ribavirin|DRUG: telaprevir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ponatinib Hydrochloride in Treating Patients With Advanced Biliary Cancer With FGFR2 Fusions
Status: COMPLETED
Conditions: Malignant Hepatobiliary Neoplasm
Interventions: OTHER: Laboratory Biomarker Analysis|DRUG: Ponatinib Hydrochloride|OTHER: Quality-of-Life Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety Study of SGN-CD19B in Patients With B-cell Non-Hodgkin Lymphoma
Status: TERMINATED
Conditions: Non-Hodgkin Lymphoma|DLBCL|Diffuse Large B-cell Lymphoma|Grade 3 Follicular Lymphoma
Interventions: DRUG: SGN-CD19B
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hybrid Treatment of Type B Aortic Dissection
Status: UNKNOWN
Conditions: Aortic Dissection Type B
Interventions: PROCEDURE: Open thoracoabdominal aortic repair + abdominal stenting|PROCEDURE: Classic thoracoabdominal aortic repair
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Benefit of Left Atrial Roof Ablation in Paroxysmal Atrial Fibrillation
Status: COMPLETED
Conditions: Drug-refractory Paroxysmal Atrial Fibrillation
Interventions: PROCEDURE: Pulmonary vein encircling|PROCEDURE: Pulmonary vein encircling plus roof ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MISSION-Vet HUD-VASH Implementation Study
Status: COMPLETED
Conditions: Substance Related Disorders|Mental Illness
Interventions: BEHAVIORAL: Maintaining Independence and Sobriety Through Systems Integration, Outreach, and Networking (Veterans Edition)|OTHER: Getting To Outcomes|BEHAVIORAL: Maintaining Independence and Sobriety Through Systems Integration, Outreach, and Networking (Veterans Edition)|OTHER: Getting To Outcomes|BEHAVIORAL: Maintaining Independence and Sobriety Through Systems Integration, Outreach, and Networking (Veterans Edition)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Trial of ARQ 197 in Patients With Unresectable Hepatocellular Carcinoma (HCC) Who Have Failed One Prior Systemic Therapy
Status: COMPLETED
Conditions: Unresectable Hepatocellular Carcinoma
Interventions: DRUG: ARQ 197|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Nafamostat Mesylate for VV-ECMO Anticoagulation
Status: RECRUITING
Conditions: Critical Illness|Anticoagulation
Interventions: DRUG: Nafamostat Mesylate|DRUG: Unfractionated Heparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Audio-recording of Consent for Anaesthesia for Elective Caesarean Section
Status: COMPLETED
Conditions: Caesarean Section|Anesthesia
Interventions: OTHER: Audio-recording of consent for anaesthesia for elective caesarean section
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effect of Sit-to-Stand Intervention in the Intensive Care Unit Survivors
Status: RECRUITING
Conditions: Unable to Sit-to-stand|ICU Survivor
Interventions: OTHER: Sit-to-stand care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Disposable Stethoscope Covers for Reduction of Stethoscope MRSA Contamination
Status: COMPLETED
Conditions: MRSA
Interventions: OTHER: Daily Antimicrobial Stethoscope Diaphragm Cover|OTHER: Uncovered Stethoscopes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of Pembrolizumab (MK-3475) Plus Chemotherapy Versus Placebo Plus Chemotherapy in Participants With Gastric or Gastroesophageal Junction (GEJ) Adenocarcinoma (MK-3475-585/KEYNOTE-585)-China Extension
Status: ACTIVE_NOT_RECRUITING
Conditions: Gastric Cancer|Gastroesophageal Junction Cancer
Interventions: BIOLOGICAL: Pembrolizumab|DRUG: Placebo|DRUG: Cisplatin|DRUG: Capecitabine|DRUG: 5-fluorouracil|DRUG: Docetaxel|DRUG: Oxaliplatin|DRUG: Leucovorin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Formulations of Biphasic Insulin Aspart 70
Status: COMPLETED
Conditions: Diabetes|Healthy
Interventions: DRUG: biphasic insulin aspart 70|DRUG: biphasic insulin aspart 70|DRUG: biphasic insulin aspart 50
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prospecta in the Treatment of Cognitive, Behavioural and Psychiatric Disorders in Patients With Vascular Dementia.
Status: COMPLETED
Conditions: Vascular Dementia
Interventions: DRUG: Prospecta|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lactate Clearance After RIPC in Liver Resection
Status: RECRUITING
Conditions: Liver Surgery|Remote Ischaemic Preconditioning
Interventions: OTHER: Remote ischaemic preconditioning|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The HepQuant SHUNT Test for Monitoring Liver Disease and Treatment Effects by Measuring Liver Function and Physiology
Status: TERMINATED
Conditions: NASH - Nonalcoholic Steatohepatitis
Interventions: COMBINATION_PRODUCT: HepQuant SHUNT Liver Diagnostic Kit
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Understanding Hemophilia A and B Drug Dosage Administration Patterns
Status: TERMINATED
Conditions: Hemophilia A|Hemophilia B
Interventions: DRUG: Hemophilia B standard half-life|DRUG: Hemophilia B extended half-life|DRUG: Hemophilia A standard half-life|DRUG: Hemophilia A extended half-life
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Emergency Department Acupuncture for Acute Musculoskeletal Pain Management
Status: COMPLETED
Conditions: Musculoskeletal Pain
Interventions: PROCEDURE: Auricular (Battlefield) Acupuncture|PROCEDURE: Peripheral Acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Compare the Pharmacokinetic Characteristics and Safety Between CKD-357 and D578 in Healthy Volunteers
Status: COMPLETED
Conditions: Acute Coronary Syndrome
Interventions: DRUG: D578|DRUG: CKD-357
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, Pharmacokinetics, and Therapeutic Efficacy of SAR441344 in Primary Sjögren's Syndrome (pSjS)
Status: COMPLETED
Conditions: Sjögren's Syndrome|Sjogren's Syndrome
Interventions: DRUG: SAR441344|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Protocol Evaluating Transient Tachypnoea of the Newborn in Term and Near Term Neonates
Status: UNKNOWN
Conditions: Transient Tachypnoea of the Newborn
Interventions: DEVICE: Echocardiography
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Short-term Telehealth Follow up After Hospital Discharge for Chronic Obstructive Pulmonary Disease Exacerbation
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: PROCEDURE: Telemonitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Long-term Effect of Marine Omega-3 Fatty Acid Supplementation in Renal Transplantation
Status: ACTIVE_NOT_RECRUITING
Conditions: Kidney Transplantation
Interventions: DRUG: Omacor|DRUG: Placebo Oral Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Frequency of Surveillance After Curative Resection in Patients With Stage II and III Colorectal Cancer
Status: UNKNOWN
Conditions: Colorectal Cancer
Interventions: PROCEDURE: CT-scan, CEA, X-ray of lungs|PROCEDURE: CT-scan, CEA, X-ray of lungs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: AX-8 Drug Safety, Tolerability and Plasma Levels in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: AX-8 Part 1|DRUG: AX-8 Part 2
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Personalized High-Definition Transcranial Direct Current Stimulation (HD-tDCS) Treatment for Major Depressive Episode
Status: RECRUITING
Conditions: Major Depressive Episode
Interventions: DEVICE: High-Definition Transcranial Direct Current Stimulation (HD-tDCS)|DRUG: Antipsychotics, mood stabilizers, etc.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Immunogenicity and Safety of GSK Biologicals' HPV Vaccine in Healthy Women Aged 18-35 Years
Status: COMPLETED
Conditions: Infections, Papillomavirus
Interventions: BIOLOGICAL: HPV-16/18 L1 VLP AS04
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Hypo-Hyperfractionated Chest Radiation for Non Small Cell Lung Cancer With Taxotere/Xeloda Combination Chemotherapy
Status: WITHDRAWN
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: Chemotherapy|PROCEDURE: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Efinaconazole 10% Solution in the Treatment of Onychomycosis in Diabetic Patients
Status: COMPLETED
Conditions: Onychomycosis
Interventions: DRUG: Efinaconazole Topical
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT