pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Efficacy and Safety of Red Ginseng Concentrated Powder on Improvement of Blood Triglyceride Level
Status: COMPLETED
Conditions: Hyperlipidemias
Interventions: DIETARY_SUPPLEMENT: Red Ginseng Concentrated Powder|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Study of SIB-IMRT in Combination With 5-FU and Mitomycin-C Among Patients With Locally Advanced Anal Canal Cancer: Efficacy, Safety and Quality of Life
Status: ACTIVE_NOT_RECRUITING
Conditions: Locally Advanced Anal Canal Cancer
Interventions: DRUG: 5Fluorouracile and Mitomycin-C|RADIATION: Simultaneously integrated boost of intensity modulated radiation therapy (SIB-IMRT) by tomotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Active Immunotherapy With Globo H-KLH (OPT-822/821) in Women Who Have Non-Progressive Ovarian Cancer
Status: UNKNOWN
Conditions: Ovarian Cancer
Interventions: BIOLOGICAL: OPT-822/OPT-821
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Adrenocorticotropic Hormone on Children With Frequent Relapse or Steroid-dependent Nephrotic Syndrome: a Prospective, Multicenter, Randomized，Open-label Clinical Trial.
Status: RECRUITING
Conditions: Nephrotic Syndrome in Children
Interventions: DRUG: Adrenocorticotrophic Hormone|DRUG: Steroid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing Two Methods of Placing an Interscalene Nerve Catheter for Postoperative Pain Control in Patients Who Undergo Open Shoulder Surgery.
Status: COMPLETED
Conditions: Shoulder Pain
Interventions: DEVICE: interscalene nerve catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: TrueBlue Clinical Study - Investigating the Use of a Mobile Phone App TrueBlue for Monitoring Depression and Anxiety
Status: NOT_YET_RECRUITING
Conditions: Depression|Depression, Postpartum|Anxiety in Pregnancy|Anxiety|Anhedonia|Perinatal Depression
Interventions: DEVICE: TrueBlue App
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Spondyloarthritis: Inducing Drug-free Remission by Early TNF-alpha Blockade
Status: RECRUITING
Conditions: Peripheral Spondyloarthritis
Interventions: DRUG: week 24|DRUG: week 36|DRUG: Week 48|DRUG: Week 60
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Outcome After Total Knee Arthroplasty Under General or Spinal Anesthesia
Status: COMPLETED
Conditions: Knee Osteoarthritis|Arthropathy of Knee Joint|Knee Pain Chronic|Rheumatoid Arthritis|Anesthesia
Interventions: PROCEDURE: Spinal anesthesia with tourniquet|PROCEDURE: Spinal anesthesia without tourniquet|PROCEDURE: General anesthesia with tourniquet|PROCEDURE: General anesthesia without tourniquet|DRUG: Oxycodone by patient-controlled analgesia (PCA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Interest of Maintenance Chemotherapy After Induction Treatment for Inflammatory Breast Cancer
Status: COMPLETED
Conditions: Inflammatory Breast Cancer
Interventions: DRUG: Docetaxel|DRUG: Cyclophosphamide|DRUG: Epirubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Open-Label Study of the Safety of Intravenous Allogeneic Neonatal Mesenchymal Cells (nMSCs) in Young Adult (1A) and Pediatric (1B) Patients With Dilated Cardiomyopathy (DCM)
Status: NOT_YET_RECRUITING
Conditions: Dilated Cardiomyopathy
Interventions: BIOLOGICAL: Allogeneic Neonatal mesenchymal stromal cells (nMSCs)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Is the NPWTi Better Than the Conventional NPWT
Status: RECRUITING
Conditions: Postoperative Wound Infection Superficial Incisional|Postoperative Wound Infection Deep Incisional Surgical Site
Interventions: DEVICE: NPWTi|DEVICE: Conventional NPWT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Metformin on Insulin Sensitivity and Pan-Arterial Vascular Function in Adults With Metabolic Syndrome
Status: COMPLETED
Conditions: Metabolic Syndrome|Insulin Sensitivity
Interventions: DRUG: Placebos|DRUG: metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Pharmacokinetics and Safety of Single-dose and Parallel Comparisons in Patients With NSCLC Treated With JS001
Status: COMPLETED
Conditions: NSCLC
Interventions: BIOLOGICAL: Toripalimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Enhanced Recovery After Surgery (ERAS) in Patients Undergoing Emergency Laparotomy
Status: RECRUITING
Conditions: Acute Abdomen|Abdominal Trauma|Emergency Surgery
Interventions: OTHER: ERAS protocols|OTHER: Conventional protocols
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating the Efficacy and Safety of Ralinepag to Improve Treatment Outcomes in PAH Patients
Status: RECRUITING
Conditions: PAH|Pulmonary Hypertension|Pulmonary Arterial Hypertension|Hypertension|Connective Tissue Diseases|Familial Primary Pulmonary Hypertension|Vascular Diseases|Cardiovascular Diseases|Hypertension, Pulmonary|Lung Diseases|Respiratory Tract Disease
Interventions: DRUG: Ralinepag|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Eccentric Training With or Without Elbow Brace for Epicondylitis
Status: UNKNOWN
Conditions: Epicondylitis|Tendinopathy|Pain
Interventions: BEHAVIORAL: Eccentric training (Flex-Bar)|DEVICE: EpiHit elbow brace
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Time Difference Between Onsets of Lateral And Medial Hamstring Muscles During Gait in Patients With Patellofemoral Pain.
Status: COMPLETED
Conditions: Patellofemoral Pain
Interventions: OTHER: kujala patellofemoral pain scale|DIAGNOSTIC_TEST: Surface EMG|OTHER: Q angle measurement
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Onset and Duration of Mometasone by Oscillometry and Spirometry
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Mometasone furoate 220|DEVICE: KoKo Spirometry|DRUG: Mometasone furoate 440|DEVICE: Oscillometry
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Investigate the Effect of Intravenous Ondansetron on Cardiac Conduction as Compared to Placebo and Moxifloxacin in Healthy Adult Subjects
Status: COMPLETED
Conditions: Nausea and Vomiting, Chemotherapy-Induced
Interventions: DRUG: ondansetron|DRUG: moxifloxacin|OTHER: saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Exploratory Study on Dosage of Qizhi Weitong Granules in the Treatment of Irritable Bowel Syndrome （IBS)
Status: UNKNOWN
Conditions: Irritable Bowel Syndrome
Interventions: DRUG: Qizhi weitong granules(High）|DRUG: Qizhi weitong granules(Low）|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intravenous N-acetylcysteine and Oseltamivir Versus Oseltamivir in Adults Hospitalized With Influenza and Pneumonia
Status: RECRUITING
Conditions: Influenza
Interventions: DRUG: N-acetyl cysteine|DRUG: 5% Dextrose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neuroprotection by Magnesium Sulfate Given to Women at Risk of Very Preterm Birth
Status: COMPLETED
Conditions: Preterm Birth|Periventricular Leukomalacia|Brain Ischemia|Intracranial Hemorrhages
Interventions: DRUG: magnesium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: PREVENTION
Clinical trial: Effect of Double Surgical Glove on Comfort, Sensitivity and Dexterity
Status: ENROLLING_BY_INVITATION
Conditions: Surgical Gloves
Interventions: OTHER: Regular Size Glove and Bigger One
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: An Upstream Palliative Care Intervention for Rural and African-American Advanced Cancer Family Caregivers
Status: COMPLETED
Conditions: Cancer, Metastatic|Family Members
Interventions: BEHAVIORAL: Project Cornerstone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Polyethylene Wear Study on the Triathlon Total Knee Prosthesis
Status: COMPLETED
Conditions: Arthroplasty, Replacement, Knee
Interventions: DEVICE: Triathlon CS fixed bearing total knee prosthesis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acupuncture for Prophylaxis of Vestibular Migraine
Status: UNKNOWN
Conditions: Vestibular Migraine
Interventions: PROCEDURE: Acupuncture|DRUG: Venlafaxine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: TMS in Preclinical and Prodromal AD: Modulation of Brain Networks and Memory
Status: UNKNOWN
Conditions: Alzheimer Disease|Mild Cognitive Impairment|Aging
Interventions: DEVICE: repetitive transcranial magnetic stimulation (rTMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study of Bevacizumab in Combination With Chemoimmunotherapy and Atezolizumab in Patients With Extensive Stage Small Cell Lung Cancer and Liver Metastases
Status: RECRUITING
Conditions: Extensive-stage Small-cell Lung Cancer|Liver Metastases
Interventions: DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Potential Pharmacokinetic Interactions Between Probe Drugs in the Geneva Phenotyping Cocktail
Status: COMPLETED
Conditions: Drug Interaction
Interventions: DRUG: Caffeine, omeprazole, flurbiprofen, dextromethorphan, midazolam|DRUG: Bupropion|DRUG: Fexofenadine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation of Micro-osteoperforations to Accelerate Orthodontic Tooth Movement
Status: COMPLETED
Conditions: Orthodontic Tooth Movement
Interventions: PROCEDURE: Micro-osteoperforations
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: High Tibial Osteotomy (HTO) With or Without Arthroscopy of the Knee Joint
Status: WITHDRAWN
Conditions: Medial Compartment Osteoarthritis of the Knee
Interventions: PROCEDURE: knee Arthroscopy|OTHER: No arthroscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Safety and Efficacy of Esperanza Extract (PA001)
Status: NOT_YET_RECRUITING
Conditions: Neoplasm, Stomach|Gastric Neoplasms Malignant|Pancreatic Neoplasms|Colorectal Neoplasms|Acute Leukemia|Acute Leukemia in Relapse|Acute Leukemia Lymphoid|Acute Myeloid Leukemia|Acute Myeloid Leukemia, in Relapse
Interventions: DRUG: Petiveria Alliacea Preparation|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Kinetics of Antibodies Against COVID-19 (SARS-CoV-2) and of Cellular Subpopulations of the Immune System
Status: UNKNOWN
Conditions: COVID-19|Healthy Volunteers|Chronic Disease|Hematological Malignancies|Solid Tumor
Interventions: BIOLOGICAL: BNT162b2|BIOLOGICAL: Other vaccine against SARS-Cov-2
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of Pneumococcal Conjugate Vaccine (V114) Compared to a Marketed Vaccine (V114-003)
Status: COMPLETED
Conditions: Pneumococcal Infections
Interventions: BIOLOGICAL: V114 Aluminum-adjuvanted|BIOLOGICAL: V114 Non-adjuvanted|BIOLOGICAL: Prevnar 13®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Ultrasound Velocimetry in the Abdominal Aorta Before and After Endovascular Aneurysm Repair
Status: COMPLETED
Conditions: Abdominal Aortic Aneurysm
Interventions: DIAGNOSTIC_TEST: EchoPIV|DIAGNOSTIC_TEST: 4D flow MRI
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Esmolol Versus Dexmedetomidine During Intracranial Procedures
Status: UNKNOWN
Conditions: Intracranial Aneurysm|Intracranial Neoplasms
Interventions: DRUG: Esmolol|DRUG: Dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Local Tolerability of Topically Applied Heparin on the Suitability of Newly Constructed Primary Arteriovenous Fistulas in Patients Planned for Haemodialysis
Status: TERMINATED
Conditions: Haemodialysis
Interventions: DRUG: Heparin 2,400 IU /ml Cutaneous Spray|DRUG: Placebo Cutaneous Spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of Postoperative Pain With or Without Apical Patency Technique in Asymptomatic Necrotic Teeth
Status: COMPLETED
Conditions: Pain, Postoperative|Acute Pain
Interventions: PROCEDURE: Apical patency with file
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Combination of Cytokine Hemosorption and High-volume Hemofiltration in Acute Pancreatitis
Status: RECRUITING
Conditions: Acute Pancreatitis Without Necrosis or Infection
Interventions: DEVICE: Efferon CT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Gut Sterilisation on Macrophage Activation in Patients With Alcoholic Hepatitis.
Status: COMPLETED
Conditions: Alcoholic Hepatitis
Interventions: DRUG: Combined Vancomycin and Gentamycin and Meropenem
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Lymphomyosot for Ankle Edema Following Fracture
Status: SUSPENDED
Conditions: Ankle Injuries|Fracture
Interventions: DRUG: Lymphomyosot|DRUG: Placebo remedy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Role of Glutathione Deficiency and MSIDS Variables in Long COVID-19
Status: NOT_YET_RECRUITING
Conditions: COVID-19
Interventions: DIETARY_SUPPLEMENT: NAC (N-acetyl cysteine) , Alpha lipoic acid (ALA), liposomal glutathione (GSH)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Impact of Fitness and Mineralocorticoid Receptor Blockade on Vascular Dysfunction in Adults With Type 1 Diabetes
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: OTHER: Exercise|DRUG: Spironolactone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacogenetic Study of Antimitotic Therapies Involved in Hepatic VOD in Children With Nephroblastoma or ALL
Status: UNKNOWN
Conditions: Hepatic Veno-Occlusive Disease|Nephroblastoma|Acute Lymphoblastic Leukemia
Interventions: OTHER: Blood test for genetic analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Local Pamidronate in Preventing Bone Loss After Total Hip Arthroplasty
Status: NOT_YET_RECRUITING
Conditions: Arthroplasty|Mineral Density
Interventions: DRUG: pamidronate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Dynamic Contrast Enhancement Computed Tomography for Evaluating Tumor Perfusion in Patients With Metastatic Renal Cell Carcinoma Receiving Targeted Therapies: Renal Cell Carcinoma (RCC) Scramble
Status: ACTIVE_NOT_RECRUITING
Conditions: Renal Cell Carcinoma
Interventions: PROCEDURE: Perfusion CT scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of CFI-400945 Fumarate in Patients With Relapsed or Refractory AML or MDS
Status: COMPLETED
Conditions: Acute Myeloid Leukemia|Myelodysplastic Syndromes|Relapsed Cancer|Refractory Cancer
Interventions: DRUG: CFI-400945 Fumarate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Pharmacokinetics and Efficacy of Bimagrumab in Overweight and Obese Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: BYM338 10 mg/kg|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Tactile-Kinesthetic Stimulation on Preterm Neonates
Status: COMPLETED
Conditions: Infant, Premature, Diseases
Interventions: PROCEDURE: Tactile-kinesthetic Stimulation|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Brain Beta-Amyloid on Postoperative Cognition
Status: RECRUITING
Conditions: Postoperative Cognitive Dysfunction
Interventions: DRUG: Florbetapir F 18 (18F-AV-45)|OTHER: no intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparison in Need for Bank Blood Between Patients Undergoing Total Hip Surgery That Either Receive Their Own Blood Back or Not
Status: COMPLETED
Conditions: Arthroplasty, Replacement, Hip|Blood Transfusion|Blood Transfusion, Autologous
Interventions: DEVICE: Sangvia® System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pranayama for Posttraumatic Stress Disorder
Status: NOT_YET_RECRUITING
Conditions: Post Traumatic Stress Disorder
Interventions: BEHAVIORAL: Pranayama assisted trauma-focused standard psychotherapy (TF-SPT)|BEHAVIORAL: Trauma-focused standard psychotherapy (TF-SPT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Topical Tranexamic Acid in Major Paediatric Spine Deformity Surgery: A Randomized Controlled Trial
Status: UNKNOWN
Conditions: Spinal Deformity, Paediatric Surgery, Tranexamic Acid
Interventions: DRUG: Topical TXA|DRUG: Intravenous TXA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Efficacy, Safety, and Tolerability of Rozanolixizumab in Adult Study Participants With Persistent or Chronic Primary Immune Thrombocytopenia (ITP)
Status: TERMINATED
Conditions: Primary Immune Thrombocytopenia
Interventions: DRUG: Rozanolixizumab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Research Into the Molecular Bases of a New Phenotype Combining Premature White Hair, Polycystic Kidney Disease, Aortic Dilation/Dissection and Lymphopenia
Status: COMPLETED
Conditions: New Phenotype (Combining Premature White Hair, Polycystic Kidney Disease, Aortic Dilation/Dissection and Lymphopenia)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Double-Blind Efficacy and Safety of CD5789 (Trifarotene) 50µg/g Cream Versus Vehicle Cream in Acne Vulgaris
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: CD5789 (trifarotene) 50µg/g Cream|DRUG: Placebo Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ABR-217620/Naptumomab Estafenatox With Interferon-alpha (IFN-alpha) Compared to IFN-alpha Alone in Patients With Advanced Renal Cell Carcinoma
Status: COMPLETED
Conditions: Renal Cell Carcinoma
Interventions: DRUG: ABR-217620/naptumomab estafenatox|DRUG: IFN-alpha
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of SmartFlow Magnetic Resonance (MR) Compatible Ventricular Cannula for Administering Eladocagene Exuparvovec to Pediatric Participants
Status: ACTIVE_NOT_RECRUITING
Conditions: AADC Deficiency
Interventions: GENETIC: Eladocagene Exuparvovec
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Contextual Interference, Engagement , and Change in Motor Performance in Stroke
Status: UNKNOWN
Conditions: Hemiparesis;Poststroke/CVA
Interventions: BEHAVIORAL: Task-specific practice of upper extremity functions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: GW572016 Combined With Trastuzumab For The Treatment Of Previously Trastuzumab-Treated Breast Cancer
Status: COMPLETED
Conditions: Neoplasms, Breast
Interventions: DRUG: GW572016 oral tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Modulation of Adaptive Immunity by Iscador® Qu Viscum Album Extract in Patients With Advanced, Recurrent or Metastatic Cancers Treated With Immune Checkpoint Inhibitors
Status: NOT_YET_RECRUITING
Conditions: Advanced Solid Tumor
Interventions: DRUG: Immune checkpoint inhibitors plus Iscador® Qu.|DRUG: Immune Checkpoint Inhibitors
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Demonstrate the Relative Bioavailability of Geneva and Dista (Prozac) 20 mg Fluoxetine Hydrochloride Capsules (Pulvules) In Healthy Adult Males Under Fed and Fasted Conditions
Status: COMPLETED
Conditions: Depression
Interventions: DRUG: Fluoxetine HCl 20 mg Capsules Under Fasting Conditions (Geneva Pharmaceutical, Inc.)|DRUG: Fluoxetine HCl 20 mg Capsules Under Fed Conditions (Geneva Pharmaceutical, Inc.)|DRUG: Prozac Fluoxetine HCl 20 mg Capsules Under Fed Conditions (Dista)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Pharmacokinetics and Pharmacodynamic Properties of Rapid-Acting Insulin Analogs
Status: COMPLETED
Conditions: Diabetes Mellitus, Type I
Interventions: DRUG: Insulin analogs (Lispro and Aspart)|DRUG: Insulin analogs (Aspart and Detemir)|DRUG: Insulin analogs (Aspart and Detemir)|DRUG: Insulin analogs (Lispro and Glargine)|DRUG: Insulin analogs (Lispro and Glargine)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lumbar Stabilization Exercises vs Flexor Exercises in Degenerative Spondylolisthesis
Status: COMPLETED
Conditions: Degenerative Spondylolisthesis|Chronic Low Back Pain
Interventions: OTHER: Lumbar stabilization exercises|OTHER: Flexor exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Relmacabtagene Autoleucel in Hematologic Malignancies
Status: NOT_YET_RECRUITING
Conditions: Lymphoma, B-Cell|Large B-cell Lymphoma|Follicular Lymphoma
Interventions: BIOLOGICAL: Relmacabtagene Autoleucel
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of Regenerative Potential in Horizontal Bone Loss Using VCMX Along With LASER Therapy
Status: RECRUITING
Conditions: Bone Loss, Alveolar
Interventions: PROCEDURE: control group: SFA only|PROCEDURE: Test group 1: VCMX + Low level LASER therapy + Single flap approach|PROCEDURE: Test group 2: Low level LASER therapy + Single flap approach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: WeChat Quit Coach Pilot Study
Status: RECRUITING
Conditions: Smoking Cessation
Interventions: BEHAVIORAL: WeChat Quit Coach|BEHAVIORAL: Leaflet|DRUG: Optional Nicotine Replacement Therapy (NRT) Patches or Lozenges
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: CD7-CART in the Treatment of r / r CD7 Positive Hemolymph System Malignancies on Increasing Dose and Open Label Study
Status: UNKNOWN
Conditions: T Lymphoblastic Leukemia/Lymphoma|Extramedullary NK-T-cell Lymphoma, Nasal Type|Peripheral T-cell Lymphoma, Nonspecific|Angioimmunoblastic T-cell Lymphoma|Enteropathy-Associated T-Cell Lymphoma|Anaplastic Large Cell Lymphoma, ALK-negative|T-cell Lymphoblastic Leukemia
Interventions: BIOLOGICAL: T cell injection targeting CD7 chimeric antigen receptor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect o f Hepatic Impairment on the Pharmacokinetics and Pharmacodynamics of Betrixiban, an Oral FXa Antagonist
Status: COMPLETED
Conditions: Hepatic Impairment
Interventions: DRUG: Betrixaban
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Clomifene Citrate Versus Metformin in First-line Treatment of Infertility in Patients With Polycystic Ovary Syndrome and a Resistance to Insulin
Status: WITHDRAWN
Conditions: Polycystic Ovary Syndrome|Insulin Resistance
Interventions: DRUG: Metformin|DRUG: Clomiphene citrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Changes in Microbiota and Metabolomic Profile Between Rifaximin Responders and Non-responders In Diarrhoea-Predominant Irritable Bowel Syndrome
Status: COMPLETED
Conditions: Irritable Bowel Syndrome With Diarrhea
Interventions: DRUG: Rifaximin Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy of 595 nm Pulsed-dye Laser in Treatment of Discoid Lupus Erythematosus
Status: UNKNOWN
Conditions: Lupus Erythematosus, Discoid
Interventions: DEVICE: Pulsed-dye Laser|DEVICE: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Characterize Nicotine Pharmacokinetics and Subjective Effects of Nicotine Pouches in Adult Cigarette Smokers
Status: COMPLETED
Conditions: Tobacco Use|Tobacco Smoking
Interventions: OTHER: Product A|OTHER: Product B|OTHER: Product C|OTHER: Product D|OTHER: Product E|OTHER: Product F|OTHER: Product G|OTHER: Product H|OTHER: Product I
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ESR 1150 CL in Healthy Subjects
Status: TERMINATED
Conditions: Healthy
Interventions: DRUG: ESR 1150 CL|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Thrombectomy In TANdem Occlusion
Status: RECRUITING
Conditions: Carotid Artery Diseases|Thrombectomy|Tandem Occlusion|Stroke
Interventions: DEVICE: Carotid Stenting|DRUG: Procedural Aspirin|DRUG: Dual dual antiplatelet therapy after 24-hours imaging follow-up|PROCEDURE: Intracranial thrombectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Crenolanib in Combination With Sorafenib in Patients With Refractory or Relapsed Hematologic Malignancies
Status: COMPLETED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Crenolanib|DRUG: Sorafenib|DRUG: methotrexate, hydrocortisone and cytarabine with leucovorin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Neuromuscular Electrical Stimulation in Individuals With Urinary Incontinence After Prostatectomy
Status: UNKNOWN
Conditions: Urinary Incontinence
Interventions: DEVICE: Neuromuscular electrical stimulation application|DEVICE: Sham neuromuscular electrical stimulation application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Circulating Tumour DNA guidEd Therapy for Stage IIB/C mElanoma After surgiCal resecTION
Status: TERMINATED
Conditions: Melanoma (Skin)|Melanoma, Stage II
Interventions: DRUG: Nivolumab 10 MG/ML
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Embryo Selection by Metabolomic Profiling of Embryo Culture Medium With Mass Spectroscopy as an Adjunct to Morphology
Status: UNKNOWN
Conditions: Embryo Selection|IVF|Morphology
Interventions: PROCEDURE: Morphology|PROCEDURE: Morphology and Mass Spectroscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Assessment of the Safety and Performance of a Compression Ankle Support in the Prevention of Injuries During Sports Practice
Status: UNKNOWN
Conditions: Chronic Pain|Chronic Instability of Ankle Joint
Interventions: DEVICE: ankleSOFT100
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: "Potential Effect of Acute and Chronic Caffeine Administration on Platelet Reactivity in Patient With Coronary Artery Disease on Dual Antiplatelet Therapy"
Status: UNKNOWN
Conditions: CORONARY ARTERY DISEASE
Interventions: OTHER: caffeine|OTHER: not caffeine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Biomarkers to Guide Directional DBS for Parkinson's Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Parkinson Disease
Interventions: DEVICE: Boston Scientific Vercise PC IPG with directional DBS lead
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study on Combined Vaccination With SARS-CoV-2 Inactivated Vaccine and Quadrivalent Influenza Vaccine
Status: COMPLETED
Conditions: COVID-19|Influenza
Interventions: BIOLOGICAL: Two doses of inactivated SARS-CoV-2 vaccine at the schedule of day 0,28 and one dose Quadrivalent Influenza Vaccine on day 0 or day 28.|BIOLOGICAL: Two doses of inactivated SARS-CoV-2 vaccine at the schedule of day 0,28 and one dose Quadrivalent Influenza Vaccine on day 14.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Sentinel Lymph Node Detection After Neoadjuvant Chemotherapy for Large Operable Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: PROCEDURE: Axillar Sentinel lymph node biopsy|PROCEDURE: SLNB and complete level I-II axillary lymphadenectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Preventing Persistent Post-Surgical Pain and Opioid Use In At-Risk Veterans: Effect of ACT
Status: COMPLETED
Conditions: Persistent Post-surgical Pain|Acceptance and Commitment Therapy|Substance Use Disorder
Interventions: BEHAVIORAL: ACT (Acceptance and Commitment Therapy)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety Study of Imexon Plus Docetaxel in Lung, Breast or Prostate Cancer Patients
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer|Breast Cancer|Prostate Cancer
Interventions: DRUG: imexon|DRUG: docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Tirzepatide Administered by Two Different Devices in Healthy Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Tirzepatide|DEVICE: Prefilled syringe (PFS)|DEVICE: Auto-injector (AI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Phase 3 Efficacy and Safety Study of VVZ-149 Injections for Postoperative Pain Following Bunionectomy
Status: UNKNOWN
Conditions: Pain, Postoperative
Interventions: DRUG: VVZ-149 Injections|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Adhesive Glue With Skin Suture for Repair of Episiotomy
Status: COMPLETED
Conditions: Mediolateral Episiotomy After Delivery
Interventions: PROCEDURE: octyl-2-cyanoacrylate adhesive glue|PROCEDURE: Subcuticular suture of perineal skin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: TOCOSOL(TM) Paclitaxel in Metastatic or Locally Advanced Unresectable Transitional Cell Carcinoma of the Urothelium
Status: COMPLETED
Conditions: Bladder Neoplasms|Ureteral Neoplasms|Urethral Neoplasms|Carcinoma, Transitional Cell
Interventions: DRUG: TOCOSOL Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Auto-adjustable Positive Airway Pressure to Continuous Positive Airway Pressure in Children With Sleep Apnea
Status: COMPLETED
Conditions: Obstructive Sleep Apnea
Interventions: DEVICE: crossover treatment (REMstar Auto A-Flex)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Examination of Acute Effects of Different Intensity Respiratory Muscle Training on Respiratory Muscle Activations
Status: NOT_YET_RECRUITING
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: OTHER: Low Intensity Respiratory Muscle Training|OTHER: Medium Intensity Respiratory Muscle Training|OTHER: High Intensity Respiratory Muscle Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy Evaluation of CHOLESWISE Pressed Candy on Cardiovascular Health
Status: COMPLETED
Conditions: Cardiovascular Diseases
Interventions: DIETARY_SUPPLEMENT: Placebo pressed candy|DIETARY_SUPPLEMENT: CHOLESWISE pressed candy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Childhood Asthma Research and Education (CARE) Network Trial - Acute Intervention Management Strategies (AIMS)
Status: COMPLETED
Conditions: Asthma|Lung Diseases
Interventions: DRUG: Inhaled Corticosteroid (Budesonide)|DRUG: Leukotriene Receptor Antagonist (Montelukast Sodium)|DRUG: Inhaled Albuterol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Are You Sitting Down: Cognitive Exectutive Function Task Comparison Between Seated and Standing Positions
Status: COMPLETED
Conditions: (Focus) Posture Effect on Cognitive Performance
Interventions: BEHAVIORAL: posture: sitting or standing
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Assess the Adverse Events and Effectiveness of BOTOX Injections for the Treatment of Moderate to Severe Forehead Lines in Chinese Adult Participants
Status: ACTIVE_NOT_RECRUITING
Conditions: Forehead Lines
Interventions: DRUG: BOTOX|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Use of Photobiomodulation After the Installation of Elastometric Separators
Status: UNKNOWN
Conditions: Orthodontic Appliance Complication
Interventions: RADIATION: Photobiomodulation|RADIATION: Placebo photobiomodulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess Efficacy and Safety of Bezafibrate in Patients With Primary Biliary Cholangitis
Status: UNKNOWN
Conditions: Primary Biliary Cirrhosis
Interventions: DRUG: Bezafibrate 200 MG Oral Tablet|DRUG: Placebo|DRUG: Ursodeoxycholic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prizvalve® Transcatheter Atrioventricular Valve Replacement Study
Status: RECRUITING
Conditions: Atrioventricular Annular Calcification|Failed Prosthetic Atrioventricular Valve/ Annulus Repair
Interventions: DEVICE: Prizvalve® system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rectal Indomethacin to Prevent Acute Pancreatitis in EUS-FNA of Pancreatic Cysts
Status: RECRUITING
Conditions: Pancreatic Cyst|Pancreatitis, Acute
Interventions: PROCEDURE: EUS-guided fine needle aspiration of pancreatic cysts
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of Pertuzumab in Combination With Herceptin in Patients With HER2 Positive Breast Cancer.
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Herceptin|DRUG: Docetaxel|DRUG: Pertuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tasigna in Glivec-resistant or Intolerant Patients in CML
Status: COMPLETED
Conditions: CML|Nilotinib|Imatinib Resistant|Imatinib Intolerant
Interventions: DRUG: nilotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study of Triple-negative Breast Cancer Brain Metastases.
Status: RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: SHR-1316|DRUG: Bevacizumab|DRUG: Cisplatin/Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Iressa With/Without Concurrent Chemoradiotherapy on Tumor Gene Expression Profiles in Patients With Advanced Non-Nasopharyngeal Head and Neck Carcinoma
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: DRUG: Gefitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Adaptive Servoventilation in Patients With Systolic Heart Failure and Sleep-Disordered Breathing
Status: COMPLETED
Conditions: Heart Failure, Congestive|Sleep Apnea Syndromes|Adaptive Servoventilation
Interventions: DEVICE: Cheyne-Stokes respiration by adaptive servoventilation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Vitamin A Supplementation for Extremely-Low-Birth-Weight Infants
Status: COMPLETED
Conditions: Infant, Newborn|Infant, Low Birth Weight|Infant, Small for Gestational Age|Infant, Premature|Bronchopulmonary Dysplasia|Respiration, Artificial|Respiratory Distress Syndrome, Newborn|Sepsis
Interventions: DRUG: Vitamin A|OTHER: Sham Procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Kinetics of the Immune Response to Inactivated Influenza Vaccine in Healthy Adults
Status: COMPLETED
Conditions: Influenza|Influenza, Human|Vaccine Reaction|Influenza A|Influenza Type B|Influenza A H1N1|Influenza A H3N2
Interventions: BIOLOGICAL: Influenza Vaccine Recipients
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Intrathrombus Thrombolysis Versus Aspiration Thrombectomy During Primary PCI
Status: RECRUITING
Conditions: Acute Coronary Syndrome|ST Elevation Myocardial Infarction|Percutaneous Coronary Intervention
Interventions: PROCEDURE: Intrathrombus Thrombolysis During Primary PCI|PROCEDURE: Aspiration Thrombectomy During Primary PCI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Switch and Maintenance Study of Intravenous Injections of R744 to Hemodialysis Patients (Phase Ⅲ Study)
Status: COMPLETED
Conditions: Hemodialysis Patients
Interventions: DRUG: R744|DRUG: R744
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study in Healthy Volunteers to Assess the Effect of Fedovapagon on the QT/QTC Interval
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Fedovapagon|DRUG: Moxifloxacin|DRUG: Placebo (for fedovapagon)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Doxorubicin Hydrochloride, Cyclophosphamide, and Filgrastim Followed By Paclitaxel Albumin-Stabilized Nanoparticle Formulation With or Without Trastuzumab in Treating Patients With Breast Cancer Previously Treated With Surgery
Status: COMPLETED
Conditions: Estrogen Receptor-positive Breast Cancer|HER2-positive Breast Cancer|Stage IA Breast Cancer|Stage IB Breast Cancer|Stage II Breast Cancer|Stage IIIA Breast Cancer|Stage IIIB Breast Cancer|Stage IIIC Breast Cancer|Stage IV Breast Cancer
Interventions: DRUG: doxorubicin hydrochloride|DRUG: cyclophosphamide|BIOLOGICAL: filgrastim|DRUG: paclitaxel albumin-stabilized nanoparticle formulation|BIOLOGICAL: trastuzumab|OTHER: laboratory biomarker analysis|PROCEDURE: quality-of-life assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Universal Chimeric Antigen Receptor-modified AT19 Cells for CD19+ Relapsed/Refractory Hematological Malignancies
Status: UNKNOWN
Conditions: Acute Lymphoblastic Leukemia|Chronic Lymphoblastic Leukemia|B-cell Lymphoma
Interventions: DRUG: Fludarabine + Cyclophosphamide + CAR-NK-CD19 Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: FK506 Phase 3 Study: a Study for Steroid Non-resistant Myasthenia Gravis (MG) Patients
Status: COMPLETED
Conditions: Myasthenia Gravis
Interventions: DRUG: tacrolimus|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Evaluate the Pharmacokinetics, Safety and Tolerability of CKD-388(2) in Healthy Subjects
Status: COMPLETED
Conditions: Chronic Hepatitis b
Interventions: DRUG: D418 Tab.|DRUG: CKD-388 Tab.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Probiotic Consumption in Children With Autism Spectrum Disorder (ASD)
Status: RECRUITING
Conditions: Autism Spectrum Disorder
Interventions: DRUG: S. boulardii CNCM (National Collection of Cultures of Microorganisms) I-745
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT