pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Nutraceutical Improvement of Glucose Metabolism, NAFLD and Insulin Resistance by Oat-fiber Supplementation in Type 2 Diabetes Mellitus Patients
Status: RECRUITING
Conditions: Type 2 Diabetes|NAFLD
Interventions: DIETARY_SUPPLEMENT: Drinking powder supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Optune TTF With Radiation as an Alternative for Elderly Patients With Primary CNS Lymphoma
Status: WITHDRAWN
Conditions: Central Nervous System Neoplasms, Primary
Interventions: DEVICE: Optune TTF device
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of a Moisturizing Cream on Vaginal and Vulvar Mucous Membranes
Status: COMPLETED
Conditions: Vaginal Dryness|Vaginal Atrophy|Vulvar Dryness|Vulvar Atrophy
Interventions: DEVICE: Moisturizing vaginal and vulvar sea buckthorn oil cream|DEVICE: Moisturizing vaginal and vulvar cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase IV O2 Consumption Study in COPD Patients.
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: DRUG: Budesonide 160 mcg and formoterol fumarate dihydrate 4.5 mcg Inhalation aerosol|DRUG: Matching Placebo pMDI 160/4.5 μg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: PalbocIclib in PreMenopausal Women With ER Positive/HER-2 Negative MetAstatic Breast Cancer
Status: UNKNOWN
Conditions: Metastatic Breast Cancer
Interventions: DRUG: Palbociclib|DRUG: Exemestane|DRUG: Goserelin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study of the Use of Rituximab in the Treatment of Chronic Focal Encephalitis
Status: COMPLETED
Conditions: Chronic Focal Encephalitis|Rasmussen's Encephalitis
Interventions: DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improving the Assessment of Hypersomnolence
Status: COMPLETED
Conditions: Disorders of Excessive Somnolence
Interventions: DEVICE: Pupillometry|BEHAVIORAL: Psychomotor Vigilance Task|OTHER: Auditory Evoked Potential|BEHAVIORAL: Hypersomnia Severity Index
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Breathing Helium-Hyperoxia During Pulmonary Rehabilitation in Patients With COPD
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease|COPD|Emphysema|Lung Diseases|Bronchitis, Chronic
Interventions: BEHAVIORAL: Helium-Hyperoxia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Michigan Youth Violence Prevention Center: Building Evidence for Gun Violence Prevention - SafERteens Implementation
Status: RECRUITING
Conditions: Violence in Adolescence
Interventions: BEHAVIORAL: Narrative Persuasion|BEHAVIORAL: Reciprocity|BEHAVIORAL: Personalized Feedback|BEHAVIORAL: Commitment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Non-surgical Periodontal Treatment on Hemogram, Lipid and Glycemic Profiles in Patients With Coronariopathies
Status: COMPLETED
Conditions: Periodontitis|Coronariopathy
Interventions: PROCEDURE: Periodontal treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Smoking Cessation With Smokeless Tobacco, Nicotine Tablets and Nicotine Patches
Status: UNKNOWN
Conditions: Tobacco Dependence
Interventions: DRUG: Smokeless tobacco (Oliver Twist pellets)|BEHAVIORAL: smoking cessation counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Moderate and High-intensity Interval Training Protocols on Biomarkers in Type 2 Diabetes Patients
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: BEHAVIORAL: MCT combined with RT Group|BEHAVIORAL: HIIT combined with RT Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Programmed Intermittent Epidural Bolus for Labor Analgesia During First Stage of Labor 2
Status: COMPLETED
Conditions: Labor Pain
Interventions: DRUG: Bupivacaine|DRUG: Fentanyl|DEVICE: Infusion pump
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ultrasound-Guided Intercostal Nerve Block for Postoperative Pain Relief in Percutaneous Nephrolitotomy
Status: COMPLETED
Conditions: Nerve Block, Intercostal Nerve
Interventions: OTHER: İntercostal nerve block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Study of Nivolumab Alone or in Combination With Ipilimumab as Immunotherapy vs Standard Follow-up in Surgical Resectable HNSCC After Adjuvant Therapy
Status: ACTIVE_NOT_RECRUITING
Conditions: Head and Neck Cancer
Interventions: PROCEDURE: Surgical resection of primary tumor|RADIATION: Adjuvant radio(-chemo)therapy|DRUG: Neoadjuvant Nivolumab|DRUG: Adjuvant Nivolumab|DRUG: Adjuvant Nivolumab and Ipilimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessing the Effects of a Buckwheat Beverage on Postprandial Glucose Metabolism on Healthy and T2D Individuals
Status: UNKNOWN
Conditions: Healthy|Type2 Diabetes
Interventions: OTHER: Dietary Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to Learn How Well a Single Dose of the Study Treatment Naproxen Sodium and Caffeine Combined in One Tablet (Fixed-dose Combination) Works to Relieve Pain After Dental Surgeries Compared to the Single Ingredients and to Placebo
Status: COMPLETED
Conditions: Postoperative Dental Pain
Interventions: DRUG: Naproxen sodium and caffeine (BAY2880376)|DRUG: Naproxen sodium (Aleve)|DRUG: Caffeine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mindfulness-based Group Therapy for Inpatients With Schizophrenia Spectrum Disorders
Status: TERMINATED
Conditions: Psychotic Disorder
Interventions: BEHAVIORAL: Mindfulness-based group therapy|OTHER: Treatment as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Oxytocin on the Acquisition and Consolidation of Trauma-Associated Memories
Status: COMPLETED
Conditions: Intrusive Memories
Interventions: DRUG: Oxytocin nasal spray|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of Baricitinib (LY3009104) in Participants With Rheumatoid Arthritis (RA)
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Baricitinib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: AMAP102 - Safety, Tolerability and Pharmacokinetics in Healthy Subjects
Status: TERMINATED
Conditions: Healthy Volunteers
Interventions: DRUG: AMAP102
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized Crossover Study on Diverse Training Methods to Enhance University Athletes' Performance and Health
Status: NOT_YET_RECRUITING
Conditions: Athletic Performance|Plyometric Exercise|Healthy
Interventions: DEVICE: Whole-Body Electrical Muscle Stimulation (WB-EMS) Training|BEHAVIORAL: Plyometric Training|BEHAVIORAL: Functional Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Metabolic Surgery for Steato-Hepatitis
Status: UNKNOWN
Conditions: Non-alcoholic Fatty Liver Disease (NAFLD)|Non-Alcoholic Steato-Hepatitis (NASH)
Interventions: PROCEDURE: Metabolic/Bariatric surgery|OTHER: Lifestyle and Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Switching From Cigarette Smoking to THS on Disease Progression in Mild to Moderate COPD Subjects With Chronic Bronchitis Symptoms.
Status: RECRUITING
Conditions: COPD|Smoking|Tobacco Use
Interventions: OTHER: THS use|OTHER: Cigarette|OTHER: Smoking Abstinence
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: AOA Versus Non-AOA in Low Prognosis Patients by the POSEIDON Criteria
Status: UNKNOWN
Conditions: in Vitro Fertilization
Interventions: PROCEDURE: ICSI with AOA|PROCEDURE: ICSI without AOA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Buspirone as a Candidate Medication for Methamphetamine Abuse
Status: COMPLETED
Conditions: Methamphetamine Dependence|Methamphetamine Abuse
Interventions: DRUG: Methamphetamine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Phase 2, Multicenter, Randomized, Open-label Study of MEDI-551 in Adults With Relapsed or Refractory Diffuse Large B-Cell Lymphoma (DLBCL)
Status: COMPLETED
Conditions: Diffuse Large B-Cell Lymphoma
Interventions: DRUG: MEDI-551 2 mg/kg|DRUG: Rituximab|DRUG: ICE|DRUG: DHAP|PROCEDURE: Autologous Stem Cell Transplant (ASCT)|DRUG: MEDI-551 4 mg/kg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigating the Effect of Liraglutide on the Endogenous Glucose Production During in Tye 1 Diabetes Subjects
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus
Interventions: DRUG: Liraglutide|DRUG: Placebo|DRUG: Mixed Meal Tolerance Test with paracetamol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pharmacokinetics and Safety of DWP14012 Tablet A and Tablet B in Healthy Volunteers (III)
Status: UNKNOWN
Conditions: Healthy
Interventions: DRUG: DWP14012 tablet A|DRUG: DWP14012 tablet B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Application of High Power Radio Frequency Energy in the Ventricular Tachycardia Treatment
Status: COMPLETED
Conditions: Ventricular Tachycardia|Heart Diseases
Interventions: PROCEDURE: High power ablation|PROCEDURE: Standard ablation power
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Steep Trendelenburg in Laparoscopic Surgery on IOP & RNFL Thickness
Status: UNKNOWN
Conditions: Intraocular Pressure|Retinal Nerve Fiber Bundle Deficiency
Interventions: DIAGNOSTIC_TEST: OCT (Optical coherence tomography)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparing the Effects of Amiodarone, Sotalol, and Placebo in Maintaining Sinus Rhythm in Patients With Atrial Fibrillation Converted to Sinus Rhythm
Status: COMPLETED
Conditions: Atrial Fibrillation|Cerebrovascular Accident|Death, Sudden
Interventions: DRUG: Amiodarone|DRUG: Sotalol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Oral Ciclosporin for Colonic Release in Ulcerative Colitis (CyCol™)
Status: COMPLETED
Conditions: Mild to Moderate Ulcerative Colitis
Interventions: DRUG: CyCol™|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multiple Respiration-Correlated Cone Beam Computed Tomography (CT) Scans to Reduce Target Positioning Errors in Radiotherapy Treatment of Thoracic Cancer
Status: COMPLETED
Conditions: Esophageal Cancer|Lung Cancer
Interventions: PROCEDURE: cone-beam CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Steady State Serum and Epithelial Lining Fluid (ELF) Antibiotics Concentrations Under Continous Infusion
Status: TERMINATED
Conditions: Pneumonia|Bacteremia
Interventions: DRUG: Meropenem|DRUG: Vancomycin|DRUG: Linezolid|DRUG: Piperacillin/Tazobactam|DRUG: Cefepim|DRUG: Ceftazidim
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Hyperbaric Oxygen for Traumatic and Non-traumatic Brain Injury
Status: COMPLETED
Conditions: Brain Injury, Chronic
Interventions: COMBINATION_PRODUCT: Hyperbaric Oxygen|COMBINATION_PRODUCT: Minimal pressure air
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Natural Killer (NK) Cells (XS005) Injection Combined With Stupp Regimen for Adjuvant Chemotherapy in Subjects With Primary Glioblastoma(GBM)
Status: RECRUITING
Conditions: Glioblastoma|GBM
Interventions: BIOLOGICAL: XS005 Cell Injection|DRUG: Temozolomide（TMZ）
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity Study of H3N2 M2SR Monovalent Influenza Vaccine in Healthy Volunteers
Status: COMPLETED
Conditions: Flu
Interventions: BIOLOGICAL: the H3N2 M2SR monovalent influenza vaccine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Short Term Effect of Hot Packs and Whirlpool for Increasing Total Active Motion at the Wrist
Status: COMPLETED
Conditions: Distal Radius Fracture
Interventions: PROCEDURE: Hot Pack|PROCEDURE: Whirlpool
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Respiratory Syncytial Virus (RSV) Human Challenge Study of Molnupiravir in Healthy Participants (MK-4482-017)
Status: COMPLETED
Conditions: Respiratory Syncytial Virus
Interventions: DRUG: Molnupiravir|DRUG: Placebo|BIOLOGICAL: RSV A Memphis 37b
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: First-in-human Safety and Tolerability of MP0317 in Patients With Relapsed/Refractory Advanced Solid Tumors
Status: TERMINATED
Conditions: Advanced Malignant Solid Tumor
Interventions: DRUG: MP0317, a tri-specific fibroblast activation protein (FAP) x CD40 DARPin® drug candidate (q3w regimen)|DRUG: MP0317, a tri-specific fibroblast activation protein (FAP) x CD40 DARPin® drug candidate (q1w regimen)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Age of OrthoInfo: A Randomized Controlled Trial Evaluating Patient Comprehension of Informed Consent
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: BEHAVIORAL: Verbal+Anatomic Model|BEHAVIORAL: Verbal+Video
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of SUNPG1622
Status: TERMINATED
Conditions: Active Ankylosing Spondylitis or Non-Radiographic Axial Spondyloarthritis
Interventions: DRUG: SUNPG1622 I dose|DRUG: Placebo dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SCRT in TNT With or Without Chlorophyllin
Status: RECRUITING
Conditions: Rectal Neoplasms
Interventions: DRUG: Chlorophyllin, Sodium Copper Complex|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Adolescent MenACWY Booster Study
Status: COMPLETED
Conditions: Meningococcal Disease, Invasive
Interventions: BIOLOGICAL: MenACWY-CRM|BIOLOGICAL: MenACWY-DT|BIOLOGICAL: MenACWY-TT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: UltraShape Device for Non-Invasive Fat Reduction in the Male Breast (Pseudogynecomastia)
Status: WITHDRAWN
Conditions: Gynecomastia|Male Breast Enlargement
Interventions: DEVICE: UltraShape focused ultrasound device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I Study of Orally Administered Aminolevulinic Acid for Resection of Malignant Astrocytomas
Status: TERMINATED
Conditions: Astrocytoma|Glioma
Interventions: DRUG: 5-Aminolevulinic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Dissemination of Comprehensive Behavioral Intervention for Tics (CBIT) to Occupational Therapists: A Feasibility Study
Status: COMPLETED
Conditions: Tourette Disorder|Chronic Tic Disorder
Interventions: BEHAVIORAL: OTs Trained and Deliver CBIT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Paraspinous Anesthetic Block for Non-Responsive Pelvic Pain
Status: COMPLETED
Conditions: Paraspinous Block|Pelvis Pain Chronic
Interventions: PROCEDURE: paraspinous anesthetic block|PROCEDURE: subcutaneous puncture with no anesthetic effect
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Patient-Directed Interactive Music Therapy on Sleep, Delirium and Melatonin Levels is Critically Ill Elderly Patients
Status: COMPLETED
Conditions: Critically Ill Adult Patients in Intensive Care Units
Interventions: BEHAVIORAL: interactive music therapy|BEHAVIORAL: passive music listening|BEHAVIORAL: passive earphone-use
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dexamethasone for COVID-19 Related ARDS: a Multicenter, Randomized Clinical Trial
Status: TERMINATED
Conditions: Respiratory Distress Syndrome, Adult|Covid-19
Interventions: DRUG: High-Dose Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Response in Chronic Hepatitis C (CHC) Participants Genotype 1 With Insulin Resistance and Prolonged Treatment Duration in Late Responders (P04823/MK-4031-303)
Status: TERMINATED
Conditions: Hepatitis C, Chronic|Insulin Resistance
Interventions: DRUG: Combination of pegylated interferon alfa-2b and ribavirin|DRUG: Combination of pegylated interferon alfa-2b and ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Darunavir in the Presence of Cobicistat When Administered as a Fixed Dose Combination Under Fed Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Darunavir|DRUG: Cobicistat|DRUG: Darunavir/Cobicistat FDC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety, Tolerability, and Efficacy Study of UBX1325 in Patients With Neovascular Age-Related Macular Degeneration (ENVISION)
Status: COMPLETED
Conditions: Neovascular Age-related Macular Degeneration
Interventions: DRUG: UBX1325 injection 50 μL|DRUG: EYLEA® (aflibercept) Injection 2 mg (0.05mL)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Neurococognitive and Functioal Assessment of Patients With Brain Metastases
Status: UNKNOWN
Conditions: Cerebral Metastases Patients
Interventions: BEHAVIORAL: neuropsychological testing and quality of life assessments|RADIATION: Standard of Care WBRT or SRS|DEVICE: Functional magnetic resonance imaging
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Investigate the Safety and Efficacy of KER-012 in Combination With Background Therapy in Adult Participants With Pulmonary Arterial Hypertension (PAH) (TROPOS Study).
Status: RECRUITING
Conditions: Pulmonary Arterial Hypertension
Interventions: BIOLOGICAL: Dose A KER-012|BIOLOGICAL: Dose B KER-012|BIOLOGICAL: Dose C KER-012|BIOLOGICAL: Placebo for 24 Weeks followed by Dose B KER-012 for 72 weeks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Platelet Aggregation in Patients With Coronary Artery Disease and Kidney Dysfunction Taking Clopidogrel or Ticagrelor
Status: COMPLETED
Conditions: Platelet Aggregation|Adenosine|Coronary Artery Disease|Kidney Dysfunction|Antiplatelet Therapy
Interventions: DRUG: Clopidogrel|DRUG: Ticagrelor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Mosapride on Postoperative Ileus in Patients Undergoing Colorectal Surgery
Status: UNKNOWN
Conditions: Postoperative Ileus
Interventions: DRUG: Mosapride|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: MRI Screening Versus SYMptom-directed Surveillance for Brain Metastases Among Patients With Triple Negative or HER2+ MBC
Status: UNKNOWN
Conditions: Breast Neoplasm|Brain Metastases|Triple Negative Breast Cancer|HER2-positive Breast Cancer
Interventions: DIAGNOSTIC_TEST: MRI screening
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Clinical Study to Assess Safety, PK and PD Parameters of CDR132L
Status: COMPLETED
Conditions: Heart Failure
Interventions: DRUG: CDR132L
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of a Customized 3D Printed Nostril Retainer Combined With Taping Vs.Taping Only on Enhancing the Nasolabial Esthetics and Maxillary Arch Dimensions in Infants With Unilateral Complete Cleft Lip and Palate.
Status: NOT_YET_RECRUITING
Conditions: Cleft Lip and Palate
Interventions: DEVICE: Customized 3D printed nostril retainer combined with lip taping|PROCEDURE: Lip taping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tranexamic Acid in Functional Endoscopic Sinus Surgery
Status: COMPLETED
Conditions: Anesthesia
Interventions: DRUG: Oral tranexamic acid|DRUG: Intravenous tranexamic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Clinical Study of ALLO-ASC-SHEET in Subjects With Diabetic Wagner Grade II Foot Ulcers
Status: RECRUITING
Conditions: Diabetic Foot Ulcer
Interventions: BIOLOGICAL: ALLO-ASC-SHEET
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 3 Efficacy and Safety Study of BAX 855 in Severe Hemophilia A Patients Undergoing Surgical Procedures
Status: COMPLETED
Conditions: Hemophilia A
Interventions: BIOLOGICAL: PEGylated Recombinant factor VIII (rFVIII)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Absorbable Suture Versus Nonabsorbable Suture Intradermal for the Skin Transverse Section in Cesarean
Status: COMPLETED
Conditions: Cesarean Section|Sutures
Interventions: OTHER: Continuous suture with polyglecaprone 25|OTHER: Continuous suture with polyamide (nylon)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: All About Youth: Evaluation of Sexual Risk Avoidance and Risk Reduction Programs for Middle School Students
Status: COMPLETED
Conditions: Sexually Transmitted Diseases|Pregnancy|HIV Infections
Interventions: BEHAVIORAL: Risk Avoidance Intervention|BEHAVIORAL: Risk Reduction Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to Compare and Evaluate Intrahepatic cccDNA Reduction After Administrating Clevudine or Entecavir in the Chronic HBV Patients
Status: TERMINATED
Conditions: Chronic Hepatitis B
Interventions: DRUG: Clevudine|DRUG: Entecavir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Esophageal Injury of a Tip CF Sensing Ablation Catheter for HP-SD of Paroxysmal and Persistent AF (ESO-SAFE-HP-RF)
Status: RECRUITING
Conditions: Atrial Fibrillation|Esophageal Perforation|Esophageal Fistula
Interventions: DEVICE: mini-invasive esophagoscopy|DEVICE: HP-SD AF ablation by a CF sensing catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluation of the Latella Knee Implant System for Medial Osteoarthritis Pain Reduction (Latella-2 Study)
Status: TERMINATED
Conditions: Osteoarthritis
Interventions: DEVICE: Latella Knee Implant System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Post-Operative Analgesic Effects of Local Wound Infiltration With Ketorolac After Inguinal Herniorrhaphy
Status: TERMINATED
Conditions: Inguinal Herniorrhaphy|Pain, Postoperative
Interventions: OTHER: Ketorolac group|OTHER: Bupivacaine group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Investigating the Effect of 4-week Omega-3 Polyunsaturated Fatty Acid Supplementation on Inflammation
Status: UNKNOWN
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Omega-3 Polyunsaturated Fatty Acids Supplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety Study of Human Recombinant Tissue Non-Specific Alkaline Phosphatase Fusion Protein Asfotase Alfa in Adults With Hypophosphatasia (HPP)
Status: COMPLETED
Conditions: Hypophosphatasia (HPP)
Interventions: BIOLOGICAL: Asfotase Alfa|BIOLOGICAL: Asfotase Alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect on Mucosal Healing With Pentasa Sachet in Mild to Moderate Active "Drug: Crohn's Disease"
Status: TERMINATED
Conditions: Crohn's Disease
Interventions: DRUG: Mesalazine (Mesalamine)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tangible Hydra-PEG: A Promising Solution for Scleral Lens Wearers With Dry Eye
Status: COMPLETED
Conditions: Dry Eye|Dry Eye Syndromes
Interventions: DEVICE: Scleral lenses treated with Tangible Hydra-PEG|DEVICE: Untreated scleral lenses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Evaluate the Pharmacokinetic Effect of SCH 503034 (Boceprevir) on Methadone or Buprenorphine/Naloxone Plasma Concentrations (P08123)
Status: COMPLETED
Conditions: Hepatitis C Virus
Interventions: DRUG: boceprevir|DRUG: methadone|DRUG: buprenorphine/naloxone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cytarabine in Combination With Arsenic Trioxide vs. Cytarabine Alone in Elderly Patients With Acute Myeloid Leukemia
Status: TERMINATED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Arsenic trioxide|DRUG: Low-dose cytarabine alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Immune Response of Adjuvanted SARS-CoV-2 (COVID-19) Beta Variant RBD Recombinant Protein (DoCo-Pro-RBD-1 + MF59®) and mRNA (MIPSCo-mRNA-RBD-1) Vaccines in Healthy Adults
Status: COMPLETED
Conditions: SARS-CoV-2
Interventions: BIOLOGICAL: Adjuvanted SARS-CoV-2 beta variant RBD recombinant protein vaccine (DoCo-Pro-RBD-1 + MF59)|BIOLOGICAL: SARS-CoV-2 beta variant RBD mRNA vaccine|OTHER: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Choice Of Optimal Strategy For Bifurcation Lesions With Normal Side Branch
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: PROCEDURE: kissing balloon|PROCEDURE: without kissing balloon angioplasty "leave alone"
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study to Compare Functional Outcomes After Surgery Using a Transverse or Longitudinal Surgical Incision in the Skin.
Status: RECRUITING
Conditions: Functional Disturbance as Result
Interventions: PROCEDURE: Longitudinal incision|PROCEDURE: Transverse incision
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CODEPAD (Collaborative Outcomes of DEpression and Pain Associated With Delivery)
Status: ACTIVE_NOT_RECRUITING
Conditions: Depression, Postpartum|Analgesia, Obstetrical|Anesthesia, Obstetrical
Interventions: DEVICE: Epidural delivery system|DRUG: Entonox|DRUG: Meperidine|DRUG: Ultiva|DRUG: Fentanyl|DRUG: Ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Varenicline for Smokeless Tobacco Use in India
Status: COMPLETED
Conditions: Tobacco Use Disorder
Interventions: DRUG: Varenicline|BEHAVIORAL: Counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Abdominal Ultrasound Assessment in the Post-cesarean Patient
Status: COMPLETED
Conditions: Postpartum Hemorrhage|Postsurgical Bleeding|Abdominal Ultrasound|FAST Scan|Non-invasive Hemoglobin Measurement
Interventions: DEVICE: FAST scan and non-invasive hemoglobin measurement
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Functional Restoration and Integrative Therapies in Service Members With Neuromusculoskeletal Injury
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Pain
Interventions: BEHAVIORAL: Complementary and Integrative Therapies|BEHAVIORAL: Standard Rehabilitative Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety Study of LY2886721 Single Doses in Healthy Subjects
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: LY2886721|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Phase II Clinical Trial of Suppression of Human Antimouse Antibody and Human Antitoxin Response to Immunotoxin LMB-1 by Rituximab
Status: COMPLETED
Conditions: Breast Neoplasms|Colonic Neoplasms|Lung Neoplasms|Pancreatic Neoplasms|Stomach Neoplasms
Interventions: DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: MED3000 Topical Gel for On-Demand Treatment of Post-Radical Prostatectomy Erectile Dysfunction
Status: RECRUITING
Conditions: Erectile Dysfunction Following Radical Prostatectomy
Interventions: DEVICE: MED3000 topical gel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intralesional Injection of Mitomycin C Following Visual Internal Urethrotomy for Recurrent Urethral Stricture
Status: COMPLETED
Conditions: Urethral Stricture
Interventions: DRUG: Mitomycin c
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Levofloxacin Combined With Intravenous Thrombolysis for Acute Ischemic Stroke
Status: RECRUITING
Conditions: Acute Ischemic Stroke
Interventions: DRUG: Levofloxacin|DRUG: Levofloxacin simulant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Influenza Immunity in Children
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Seasonal IIV 0.25 mL dose|OTHER: Natural influenza infection|BIOLOGICAL: Seasonal IIV 0.5 mL dose
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Nimotuzumab Combined With Radiotherapy for Older Patients With Esophageal Cancer: a Single, Non-control Clinical Trial
Status: COMPLETED
Conditions: Esophageal Cancer
Interventions: DRUG: Nimotuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of the Steroid-Eluting Sinexus Intranasal Splint When Used Following Functional Endoscopic Sinus Surgery (FESS) in Patients With Chronic Sinusitis
Status: COMPLETED
Conditions: Chronic Sinusitis
Interventions: DEVICE: Steroid-Eluting Sinexus Intranasal Splint
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Cooperative Pain Education and Self-management: Expanding Treatment for Real-world Access (COPES ExTRA)
Status: ACTIVE_NOT_RECRUITING
Conditions: Pain, Chronic
Interventions: BEHAVIORAL: COPES|BEHAVIORAL: CBT-CP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Study to Assess the Safety and Immunogenicity of recMAGE-A3+AS15 ASCI With or Without Poly IC:LC
Status: TERMINATED
Conditions: Melanoma
Interventions: DRUG: MAGE-A3 ASCI injections without Poly IC:LC|DRUG: MAGE-A3 ASCI injections with Poly IC:LC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 1b/2 Study of BGB-11417in Monotherapy and in Various Combinations With Dexamethasone and Carfilzomib in Multiple Myeloma
Status: RECRUITING
Conditions: Relapsed/Refractory Multiple Myeloma
Interventions: DRUG: BGB-11417|DRUG: Dexamethasone|DRUG: Carfilzomib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Based on Data From German Sick Funds That Looks at the Costs of Treatment of Type-2 Diabetic Patients With Empagliflozin vs. DPP-4 Inhibitors vs. GLP-1 Receptor Agonists
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Empagliflozin|DRUG: DPP-4i|DRUG: GLP-1-RA
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study on the Effects of a Recommendation Based Supply of Vitamin D3 in Healthy Volunteers
Status: COMPLETED
Conditions: Deficiency of Vitamin D3
Interventions: DIETARY_SUPPLEMENT: Vitamin D3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial Using ARV-471 or Anastrozole in Post-Menopausal Women With Breast Cancer Prior to Surgery
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: ARV-471|DRUG: Anastrozole|PROCEDURE: Surgical resection of breast tumor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Pharmacodynamics of SEL-037 (Pegsiticase) in Subjects With Elevated Blood Uric Acid Levels
Status: COMPLETED
Conditions: Gout
Interventions: BIOLOGICAL: SEL-037 (pegsiticase)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Narazaciclib (ON 123300) Plus Letrozole in Endometrial Cancer and Other Gynecologic Malignancies
Status: RECRUITING
Conditions: Endometrioid Endometrial Cancer
Interventions: DRUG: Narazaciclib|DRUG: Letrozole 2.5mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rapid Diagnostics for HIV and Hepatitis
Status: WITHDRAWN
Conditions: HIV Infections|Hepatitis B Infections|Hepatitis C Infections
Interventions: DEVICE: Multiplo HBc/HIV/HCV and Reveal HBsAg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Gemcitabine Hydrochloride and Cisplatin With or Without Veliparib or Veliparib Alone in Treating Patients With Locally Advanced or Metastatic Pancreatic Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Locally Advanced Pancreatic Adenocarcinoma|Metastatic Pancreatic Adenocarcinoma|Stage III Pancreatic Cancer AJCC v8|Stage IV Pancreatic Cancer AJCC v8
Interventions: PROCEDURE: Biopsy|PROCEDURE: Biospecimen Collection|DRUG: Cisplatin|PROCEDURE: Computed Tomography|DRUG: Gemcitabine|DRUG: Gemcitabine Hydrochloride|PROCEDURE: Magnetic Resonance Imaging|DRUG: Veliparib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Looking Beyond the Immediate Effects of Lumbar Spinal Manipulation Using Pain Pressure Threshold in Asymptomatic Individuals
Status: COMPLETED
Conditions: Lumbar Spine Injury|Pain
Interventions: PROCEDURE: Sidelying lumbar manipulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Maximum Tolerable Concentration of abnobaVISCUM Fraxini Intravesically in Patients With Superficial Bladder Cancer
Status: COMPLETED
Conditions: Superficial Bladder Cancer
Interventions: DRUG: abnobaVISCUM Fraxini
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of an Echographic Algorithm on Hemodynamic Optimization in the First 4 Days of Septic Shock Management
Status: RECRUITING
Conditions: Shock, Septic|Hemodynamic Instability
Interventions: OTHER: Echographic hemodynamic algorithm guiding fluid resuscitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Intraventricular Fibrinolysis for Aneurysmal Subarachnoid Hemorrhage.
Status: SUSPENDED
Conditions: Subarachnoid Hemorrhage
Interventions: DRUG: EVD + IVF with Alteplase
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Switching Anti-TNF-Alpha Agents in Rheumatoid Arthritis (RA)
Status: TERMINATED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Adalimumab|DRUG: Adalimumab placebo|DRUG: Etanercept
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of Parent-Child Interaction Therapy (PCIT)
Status: COMPLETED
Conditions: Behavior Problems|Oppositional Defiant Disorder|Conduct Disorder
Interventions: BEHAVIORAL: Parent-Child Interaction Therapy|BEHAVIORAL: TAU
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimization of NULOJIX® Usage As A Means of Avoiding CNI and Steroids in Renal Transplantation
Status: TERMINATED
Conditions: Kidney Transplantation|Renal Transplantation
Interventions: DRUG: Alemtuzumab|DRUG: MMF|BIOLOGICAL: Basiliximab|DRUG: Short-term Tac|DRUG: tacrolimus|BIOLOGICAL: Belatacept|DRUG: methylprednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 4 mA tDCS, Estrogen, and Leg Muscle Fatigability
Status: COMPLETED
Conditions: Healthy
Interventions: DEVICE: Sham transcranial direct current stimulation 4 mA|DEVICE: Transcranial direct current stimulation 4 mA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Cognitive Restructuring Before Exposure for Claustrophobia on Expectancy and Outcome
Status: COMPLETED
Conditions: CR Before:Engaging in Cognitive Intervention Before Exposure|CR After:Engaging in Cognitive Intervention After Exposure
Interventions: BEHAVIORAL: CR Before Exposure|BEHAVIORAL: CR After Exposure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Electronic Skin Surface Brachytherapy for Cutaneous Basal Cell and Squamous Cell Carcinoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Cutaneous Basal Cell|Squamous Cell Carcinoma
Interventions: RADIATION: Electronic Skin Surface Brachytherapy|BEHAVIORAL: Quality of life assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasonographic Assessment of Lung Recruitment Maneuvers in Children Undergoing Lengthy Microsurgery Operations
Status: COMPLETED
Conditions: Intraoperative Complications
Interventions: DEVICE: RM 0.5|DEVICE: RM 0.3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Minimum Effective Concentration of Bupivacaine (EC50) in Femoral Block for Analgesia by Ultrasound After Knee Surgery
Status: COMPLETED
Conditions: Knee Surgery|Postoperative Pain
Interventions: DRUG: Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Lidocaine-Prilocaine Cream (EMLA) Topical Application Versus Wound Infiltration With Lidocaine After Cesarean Section
Status: UNKNOWN
Conditions: Post Operative Pain
Interventions: DRUG: EMLA CREAM 5 mg|DRUG: LIDOCAINE 1 %
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pivotal Bioequivalence Study of Topically Delivered Halobetasol Propionate Ointment in Normal Skin in Healthy Adult Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Halobetasol Propionate 0.05% Ointment, single exposure|DRUG: Ultravate® 0.05% ointment, single exposure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: Comparison of Two Formulations of Proellex for Vaginal Administration
Status: COMPLETED
Conditions: Comparison of 2 Different Formulations of 12 mg Proellex Vaginal Capsules
Interventions: DRUG: Proellex Formulation A|DRUG: Proellex Formulation B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of the Valiant Captivia Physician Fenestrated Stent Graft System in Aortic Arch and Descending Thoracic Aorta Pathologies
Status: RECRUITING
Conditions: Penetrating Ulcer of Aorta|Aneurysm Aortic|Type B Aortic Dissection|Residual Dissection After Type A Repair
Interventions: DEVICE: The Valiant Captivia Stent Graft
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pemetrexed and Oxaliplatin in Treating Patients With Metastatic Solid Tumors or Lymphoma
Status: COMPLETED
Conditions: Lymphoma|Solid Tumor
Interventions: DRUG: oxaliplatin|DRUG: pemetrexed disodium
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT