pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: IPT-based Group Intervention by Non-specialist for Improvement of Depressive Symptoms in Community Young Adults in Brazil
Status: RECRUITING
Conditions: Depression|Interpersonal Relations
Interventions: BEHAVIORAL: Interpersonal psychotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acute Vascular Effects of E-cigarette Use
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: E-cigarette vapor containing nicotine|OTHER: E-cigarette vapor, nicotine free
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of JNJ-39758979 in Adult Japanese Patients With Moderate Atopic Dermatitis
Status: TERMINATED
Conditions: Dermatitis, Atopic
Interventions: DRUG: JNJ-39758979, 300 mg|DRUG: JNJ-39758979, 100 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics and Tolerancebility Studies of Gentuximab Injection in the Treatment ofPatients With Late Recurrence of Metastatic Solid Tumors in China
Status: UNKNOWN
Conditions: Solid Tumor
Interventions: DRUG: Gentuximab Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Protective Ventilation in Neurosurgery, a Pilot Study
Status: COMPLETED
Conditions: Nervous System Neoplasms
Interventions: PROCEDURE: Traditional to protective ventilation|PROCEDURE: Protective to traditional ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of SLITone in House Dust Mite Allergic Patients
Status: COMPLETED
Conditions: Allergy
Interventions: BIOLOGICAL: SLITone(TM) Dermatophagoides mix|BIOLOGICAL: Placebo|DRUG: Salbutamol inhaler|DRUG: Budesonide/formoterol inhaler|DRUG: Prednisone tablet|DRUG: Desloratadine tablet|DRUG: Budesonide nasal spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Telavancin and Vancomycin for Complicated Skin and Skin Structure Infections With a Focus on Methicillin-resistant Staphylococcus Aureus
Status: COMPLETED
Conditions: Staphylococcal Skin Infection
Interventions: DRUG: Telavancin|DRUG: Vancomycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ixabepilone in Treating Patients With Relapsed or Refractory Aggressive Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Anaplastic Large Cell Lymphoma|Recurrent Adult Burkitt Lymphoma|Recurrent Adult Diffuse Large Cell Lymphoma|Recurrent Adult Diffuse Mixed Cell Lymphoma|Recurrent Grade 3 Follicular Lymphoma|Recurrent Mantle Cell Lymphoma
Interventions: DRUG: ixabepilone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Contract-Relax (CR) Technique in the Management of Diaphragmatic Paresis After Cardiac Surgery
Status: COMPLETED
Conditions: Surgery, Cardiac
Interventions: PROCEDURE: Usual physical therapy|PROCEDURE: Contract-Relax technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PET Imaging to Delineate Macrophage Activation in Diabetic Gastroparesis
Status: COMPLETED
Conditions: Diabetes|Gastroparesis With Diabetes Mellitus
Interventions: DRUG: PET/CT Scan with 11C-ER176|DIAGNOSTIC_TEST: Core biopsy of gastric muscle
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Telenursing and Adherence to Stains in Patients With Diabetes
Status: COMPLETED
Conditions: Telenursing Lipid Lowering Medication Adherence
Interventions: OTHER: SMS reminder massages about adherence
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Duration of Antibiotics in Infective Exacerbations of Cystic Fibrosis
Status: UNKNOWN
Conditions: Cystic Fibrosis
Interventions: DRUG: Ceftazidime|DRUG: Tobramycin|DRUG: Meropenem
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Sub-symptom Threshold Aerobic Exercise After Mild Traumatic Brain Injury
Status: ACTIVE_NOT_RECRUITING
Conditions: Mild Traumatic Brain Injury
Interventions: OTHER: Sub-symptom threshold aerobic exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Entecavir and Tenofovir Versus Entecavir in Lymphoma Patients With Positive HBV DNA
Status: UNKNOWN
Conditions: B-cell Lymphoma|HBV
Interventions: DRUG: Tenofovir|DRUG: Entecavir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Efficacy of I-Prf Impregnated Collagen and L-Prf on Healing After Impacted Third Molar Surgery
Status: ACTIVE_NOT_RECRUITING
Conditions: Impacted Third Molar Tooth
Interventions: PROCEDURE: I-PRF with collagen|PROCEDURE: L-PRF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Immunotherapy Using Precision T Cells Specific to Personalized Neo-antigen for the Treatment of Advanced Malignant Tumor of Biliary Tract
Status: UNKNOWN
Conditions: Advanced Biliary Tract Malignant Tumor
Interventions: DRUG: Gemcitabine|BIOLOGICAL: Dendritic cell-precision T cell for neo-antigen combined with gemcitabine treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Irinotecan and Etoposide in Treating Patients With Recurrent, Locally Advanced, or Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Etoposide|DRUG: Irinotecan hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Wild Blueberries on Depressive Symptoms in Young Adults
Status: COMPLETED
Conditions: Depression|Anxiety|Anhedonia
Interventions: DIETARY_SUPPLEMENT: Wild blueberry powder|DIETARY_SUPPLEMENT: Placebo powder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II Clinical Trial of Uncaria Tomentosa (Cat´s Claw) in Patients With Advanced Solid Tumors
Status: UNKNOWN
Conditions: Solid Tumors
Interventions: DRUG: uncaria tomentosa (cat´s claw)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A First in Human Study of BAY2701439 to Look at Safety, How the Body Absorbs, Distributes and Excretes the Drug, and How Well the Drug Works in Participants With Advanced Cancer Expressing the HER2 Protein
Status: COMPLETED
Conditions: Cancers With HER2 Expression
Interventions: DRUG: BAY2701439|DRUG: BAY2701439
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Iontophoretic Dexamethasone Phosphate Ophthalmic Solution in Non-Infectious Anterior Uveitis
Status: COMPLETED
Conditions: Anterior Uveitis
Interventions: DRUG: Dexamethasone Phosphate Ophthalmic Solution|DRUG: Prednisolone Acetate Ophthalmic (1%)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Early Versus Late Initiation of Edaravone Dexborneol on Neural Function in Patients With Acute Ischemic Stroke
Status: NOT_YET_RECRUITING
Conditions: Ischemic Stroke, Acute|Treatment Outcome
Interventions: DRUG: Edaravone Dexborneol Concentrated Solution for injection|DRUG: Edaravone Dexborneol placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Tislelizumab Combined With Concurrent Chemoradiotherapy for Locally Advanced Cervical Cancer
Status: RECRUITING
Conditions: Uterine Cervical Neoplasms
Interventions: DRUG: Tislelizumab|DRUG: DDP synchronous with radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 1b/2a, Study Evaluating the Safety, PK/PD and Efficacy of NS101 in Healthy Volunteers and SSNHL Patients
Status: RECRUITING
Conditions: Seneorineural Deafness|Sudden Sensorineural Hearing Loss
Interventions: BIOLOGICAL: NS101|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cyclophosphamide, Paclitaxel, and Trastuzumab in Treating Stage I-II HER2/Neu Positive Breast Cancer After Surgery
Status: ACTIVE_NOT_RECRUITING
Conditions: HER2 Positive Breast Carcinoma|Stage I Breast Cancer AJCC v7|Stage IA Breast Cancer AJCC v7|Stage IB Breast Cancer AJCC v7|Stage II Breast Cancer AJCC v6 and v7|Stage IIA Breast Cancer AJCC v6 and v7|Stage IIB Breast Cancer AJCC v6 and v7
Interventions: DRUG: Cyclophosphamide|OTHER: Laboratory Biomarker Analysis|DRUG: Paclitaxel|BIOLOGICAL: Trastuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Implementing CAPABLE in PSH
Status: COMPLETED
Conditions: Accidental Fall|Frailty|Depression|Activities of Daily Living|Housing Problems
Interventions: BEHAVIORAL: CAPABLE: Community Aging in Place-Advancing Better Living for Elders
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of the Neointimal Healing by OCT of the Tapered DES Biomime Morph (TAPER-I Study)
Status: COMPLETED
Conditions: Atherosclerosis
Interventions: DEVICE: Biomime Morph, a tapered drug eluting stent (DES) with hybrid design
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase III Double-blind Study With Idebenone in Patients With Duchenne Muscular Dystrophy (DMD) Taking Glucocorticoid Steroids
Status: TERMINATED
Conditions: Duchenne Muscular Dystrophy (DMD)
Interventions: DRUG: Idebenone 150 mg film-coated tablets|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Neoadjuvant Chemoradiation Plus Serplulimab in Patients With Locally Advanced Adenocarcinoma of Gastroesophageal Junction
Status: RECRUITING
Conditions: Gastroesophageal Junction Adenocarcinoma
Interventions: DRUG: Serplulimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immediate Implant Placement With Connective Tissue Graft or Socket Shield
Status: UNKNOWN
Conditions: Tooth Fractures
Interventions: PROCEDURE: Connective tissue graft|PROCEDURE: socket shield technique|PROCEDURE: Immediate implant placement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Placebo-Controlled, Single-Dose Challenge Study of Gaboxadol in Adult Males With Fragile X Syndrome (FXS)
Status: RECRUITING
Conditions: Fragile X Syndrome
Interventions: DRUG: Gaboxadol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Regimen for the Treatment of Cachexia in Subjects With NSCLC
Status: COMPLETED
Conditions: Cachexia
Interventions: DRUG: VT-122 low dose|DRUG: VT-122 high dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Evaluate Efficacy and Safety of SAR441566 in Adults With Plaque Psoriasis
Status: RECRUITING
Conditions: Psoriasis
Interventions: DRUG: SAR441566|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Evaluation of Inhaled Treprostinil Administration Following Transition From Inhaled Ventavis in Pulmonary Arterial Hypertension (PAH) Subjects
Status: COMPLETED
Conditions: Pulmonary Arterial Hypertension
Interventions: DRUG: Inhaled treprostinil
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Empower: tDCS for Major Depressive Disorder at Home
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DEVICE: Transcranial direct current stimulation|DEVICE: Sham Transcranial direct current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Fruquintinib Plus Capecitabine Versus Capecitabine as Maintenance Therapy for Metastatic Colorectal Cancer After First-line Chemotherapy
Status: NOT_YET_RECRUITING
Conditions: Colorectal Cancer|Colorectal Cancer Stage IV
Interventions: DRUG: Fruquintinib Plus Capecitabine|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of a Nutraceutical Preparation on Cognitive Impairment in Hypertensive Patients
Status: COMPLETED
Conditions: Hypertension
Interventions: DIETARY_SUPPLEMENT: Nutraceutical compound|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Atrial Fibrillation and Ischemic Events With Rivaroxaban in Patients With Stable Coronary Artery Disease Study
Status: UNKNOWN
Conditions: Atrial Fibrillation
Interventions: DRUG: Rivaroxaban and single antiplatelet drug (aspirin, clopidogrel or prasugrel)|DRUG: Rivaroxaban
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility of Telehealth Problem-Solving Therapy for Depressed Homebound Older Adults
Status: COMPLETED
Conditions: Depression
Interventions: BEHAVIORAL: Tele-Problem-Solving Therapy|BEHAVIORAL: In-Person PST|BEHAVIORAL: Attention control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Brentuximab Vedotin in Relapsed/Refractory Germ Cell Tumors
Status: TERMINATED
Conditions: Germ Cell Tumors|Testis Cancer|Testicular Cancer|Embryonal Carcinoma|Nonseminomatous Germ Cell Tumor
Interventions: DRUG: Brentuximab Vedotin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Usefulness of Adopting Remote, Mobile-based 6MWT Among Hospital Outpatients (the 6-APPnow), Within the Constraints Imposed by the SARS-COV2 Pandemic
Status: COMPLETED
Conditions: Pulmonary Hypertension
Interventions: OTHER: App
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Role of Rotator Interval Closure in Bankart Lesion Repair
Status: UNKNOWN
Conditions: Bankart Lesions|Anterior Shoulder Instability
Interventions: OTHER: Arthroscopic Bankart Repair alone|PROCEDURE: Closure of rotator interval
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Osmotic Therapy for Treatment of Intracranial Hypertension for Traumatic Brain Injury
Status: WITHDRAWN
Conditions: Traumatic Brain Injury
Interventions: DRUG: Mannitol|DRUG: NaCl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Targeting Apathy With Music in Parkinson's Disease
Status: RECRUITING
Conditions: Parkinson Disease|Apathy
Interventions: OTHER: Music listening|OTHER: Podcast listening
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Electroacupuncture in Patients Submitted Orthognathic Surgery and Mentoplasty
Status: RECRUITING
Conditions: Paresthesia|Edema
Interventions: OTHER: Physiotherapy and Electroacupuncture|OTHER: Physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Epithelial Healing and Visual Outcomes Using Omega-3 Therapy Before and After Photorefractive Keratectomy (PRK) Surgery
Status: COMPLETED
Conditions: Refractive Error
Interventions: DIETARY_SUPPLEMENT: Omega-3 Fatty Acid Supplements
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Parallel Versus Perpendicular Technique for Lumbar Medial Branch Radiofrequency Neurotomy
Status: RECRUITING
Conditions: Back Pain Without Radiation|Low Back Pain|Lumbar Radiofrequency Neurotomy
Interventions: PROCEDURE: Parallel placement of 16 gauge electrodes|PROCEDURE: Perpendicular placement with 22 gauge electrodes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Proportion of Clinical Improvement & Type 1 Interferon (IFN) Score Changes in Idiopathic Uveitis Patients With Interferon Gamma Release Assay (IGRA) Positive
Status: RECRUITING
Conditions: Tuberculosis; Uveitis (Manifestation)|Anti-Tuberculous Drug Reaction|Tuberculous Uveitis
Interventions: DRUG: Fixed drug combination (FDC) of ATT and Oral steroid
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Transitioning From Alendronate to Denosumab
Status: COMPLETED
Conditions: Postmenopausal Osteoporosis
Interventions: DRUG: alendronate|DRUG: Denosumab (AMG 162)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of a Modified Mindfulness-based Cognitive Therapy for Family Caregivers of People With Dementia
Status: COMPLETED
Conditions: Carer Stress Syndrome|Dementia
Interventions: BEHAVIORAL: Modified MBCT|BEHAVIORAL: SIRE on dementia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Specific Neurodynamic Exercises on Disability and Neck Pain in Old Women
Status: COMPLETED
Conditions: Neck Pain
Interventions: PROCEDURE: specific neurodynamic exercises|PROCEDURE: multimodal exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Postural Correction Exercises in Reducing Forward Head Posture in Children Carrying Heavy Bag Packs
Status: COMPLETED
Conditions: Postural Kyphosis
Interventions: OTHER: strengthening exercise|OTHER: Postural correction exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Platelet-rich Plasma Nasal Injection in the Treatment of Traumatic Olfactory Dysfunction
Status: NOT_YET_RECRUITING
Conditions: Traumatic Olfactory Nerve Injury With Anosmia (Diagnosis)|Effect of Drug
Interventions: COMBINATION_PRODUCT: platelet-rich plasma combined with hyaluronic acid|DRUG: Zinc Gluconate 10 MG Oral Tablet|DEVICE: 4 bottles of phenyl ethyl alcohol, lemon, eucalyptus, and clove oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Scapular Exercises in Patients With Stroke
Status: COMPLETED
Conditions: Stroke, Acute
Interventions: OTHER: Bobath Approach|OTHER: Isometric scapular exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Outcomes and Radiation Safety After Endovascular Repair of Complex AAAs Using Fenestrated- Branched Devices
Status: ENROLLING_BY_INVITATION
Conditions: Aortic Aneurysm, Abdominal|Thoracic Aneurysm
Interventions: DEVICE: Fenestrated CMD|DEVICE: Type I - III TAAA|DEVICE: Arch cohort
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Of Non-Invasive High Power Laser Acupuncture Stimulation In Chronic Non-Specific Low Back Pain
Status: RECRUITING
Conditions: Low Back Pain
Interventions: OTHER: high power laser acupuncture (HPLA)|OTHER: conventional treatment|OTHER: Sham laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Telerehabilitation Cognitive Impairments Following Chemotherapy Feasibility Study
Status: UNKNOWN
Conditions: Cognitive Impairment, Mild
Interventions: DEVICE: Telerehabilitation Experimental Group|OTHER: Telerehabilitation Sham Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Amantadine Treatment in COVID-19 Patients
Status: TERMINATED
Conditions: Patients With Moderate or Severe COVID-19
Interventions: DRUG: Amantadine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: RCT: Difference in Diagnostic Yield Between EUSFNA Needles With and Without a Side Port in Pancreatic Masses
Status: COMPLETED
Conditions: Pancreatic Neoplasm|Pancreatic Diseases
Interventions: DEVICE: Needle with sideport (NA-230H-8020)|DEVICE: Needle without sideport (NA-220H-8022)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of a Single Subcutaneous Dose of JNJ-26366821 in Healthy Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: JNJ-26366821|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Development of Products Based on Secretom From Stem Cell Conditioned Medium for Melasma Therapy
Status: RECRUITING
Conditions: Melasma
Interventions: DRUG: Concentrated secretome Injection 2mL|DRUG: Tranexamic acid injection|DRUG: Triple Combination Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Antiplatelet Effects of Tirofiban vs. Cangrelor N-STEMI Patients Undergoing Percutaneous Coronary Intervention
Status: TERMINATED
Conditions: Non-ST Elevation Myocardial Infarction (NSTEMI)
Interventions: DRUG: Tirofiban|DRUG: Cangrelor
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Delayed Cord Clamp and/or Indomethacin on Preterm Infant Brain Injury
Status: COMPLETED
Conditions: Intraventricular Hemorrhage|Periventricular Leukomalacia|Brain Injury|Renal Injury
Interventions: DRUG: Indomethacin|PROCEDURE: delay in umbilical cord clamp at birth|DRUG: placebo infusion|PROCEDURE: immediate cord clamp at birth
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Botulism Antitoxin Effects on Paralysis Induced by Botulinum Neurotoxins in the EDB Muscle
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: BIOLOGICAL: Botulism Antitoxin Bivalent (Equine) Types A and B|BIOLOGICAL: Botulism Antitoxin Heptavalent (Equine) Types A-G
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Secretin Enhanced Multidetector CT Pancreatography for Evaluation of Known or Suspected Chronic Pancreatitis
Status: TERMINATED
Conditions: Chronic Pancreatitis
Interventions: DRUG: RG1068 (Synthetic Human Secretin)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of the Combination of Ibrutinib Plus Venetoclax Versus Chlorambucil Plus Obinutuzumab for the First-line Treatment of Participants With Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL)
Status: ACTIVE_NOT_RECRUITING
Conditions: Leukemia, Lymphocytic, Chronic, B-Cell
Interventions: DRUG: Ibrutinib|DRUG: Venetoclax|DRUG: Chlorambucil|DRUG: Obinutuzumab|DRUG: Ibrutinib (as Subsequent Therapy)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase II/III Study of PIKA Recombinant SARS-CoV-2 Vaccine as a Booster Dose.
Status: COMPLETED
Conditions: Covid-19 Vaccine
Interventions: BIOLOGICAL: PIKA COVID-19 vaccine|BIOLOGICAL: Inactivated Covid-19 vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Oral Procaterol on Postinfectious Persistent Cough
Status: UNKNOWN
Conditions: Cough
Interventions: DRUG: Procaterol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Abemaciclib (LY2835219) in Combination With Other Anti-Cancer Treatments in Children and Young Adult Participants With Solid Tumors, Including Neuroblastoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Relapsed Solid Tumor|Refractory Solid Tumor
Interventions: DRUG: Abemaciclib|DRUG: Irinotecan|DRUG: Temozolomide|DRUG: Dinutuximab|DRUG: GM-CSF
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 1/2 Trial of Donor Regulatory T-cells for Steroid-Refractory Chronic Graft-versus-Host-Disease
Status: UNKNOWN
Conditions: Graft vs Host Disease
Interventions: BIOLOGICAL: Donor regulatory T cell adoptive immunotherapy in chronic graft versus host disease
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of PLB1001 Enteric Capsules in the Treatment of sGBM/IDH Mutant Glioblastoma Patients With the ZM Fusion Gene (FUGEN).
Status: ACTIVE_NOT_RECRUITING
Conditions: Glioblastoma
Interventions: DRUG: PLB1001|DRUG: Temozolomide|DRUG: Cisplatin combined with Etoposide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Effect of Vedolizumab on Intestinal Microecological Changes and Its Efficacy in the Treatment of Ulcerative Colitis
Status: UNKNOWN
Conditions: Ulcerative Colitis
Interventions: DRUG: Vedolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study of Ravulizumab in Children and Adolescents With Atypical Hemolytic Uremic Syndrome (aHUS)
Status: COMPLETED
Conditions: Atypical Hemolytic Uremic Syndrome (aHUS)
Interventions: BIOLOGICAL: Ravulizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Study of Intensity Modulated Radiotherapy in Dose Painting for Sinus Carcinomas After Endoscopic Surgery
Status: RECRUITING
Conditions: Tumor, Solid
Interventions: RADIATION: Radiotherapy in painting dose on histoscannographic mapping|RADIATION: Standard pan-sinusal Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: rESP Medication With a Single Intravenous Administration and Dose Escalation to Explore the Tolerability ,Safety and Pharmacokinetic Characteristics
Status: UNKNOWN
Conditions: Chronic Renal Failure
Interventions: DRUG: Recombinant erythropoietin stimulating protein
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Whey Protein Consumption by Patients Waiting for Liver Transplantation
Status: UNKNOWN
Conditions: Liver Disease|Nutrition Disorders
Interventions: DIETARY_SUPPLEMENT: Whey protein
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Clinical Evaluation of the Safety and Performance of a Filler in Correction of Mid-face Age-related Volume Deficit
Status: COMPLETED
Conditions: Aesthetics|Intradermal Injections
Interventions: DEVICE: DEFINISSE CORE FILLER
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Between HIIT and MICT on the Phase III of Cardiac Rehabilitation
Status: COMPLETED
Conditions: Patients With Coronary Artery Disease
Interventions: OTHER: High Intensity Interval Training Program|OTHER: Moderate Intensity Continuous Training Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Safety and Immunogenicity of Enerceptan Compared to Enbrel in Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: BIOLOGICAL: Etanercept|DRUG: Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Reducing Risk Factors in Peripheral Arterial Disease
Status: COMPLETED
Conditions: Cardiovascular Diseases|Peripheral Vascular Diseases
Interventions: BEHAVIORAL: Health-Counselor Mediated Telephone Counseling Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Caloric Restriction and Activity to Reduce Chemoresistance in B-ALL
Status: RECRUITING
Conditions: B-cell Acute Lymphoblastic Leukemia|Obesity
Interventions: BEHAVIORAL: IDEAL2 Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety, Tolerability and Immunogenicity of NBP607QIV in Healthy Adult Volunteers
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: NBP607QIV|BIOLOGICAL: Agrippal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Taurine Supplementation and Triathletes
Status: COMPLETED
Conditions: Athletic Proteinuria
Interventions: DIETARY_SUPPLEMENT: TAUchoc|DIETARY_SUPPLEMENT: PLAchoc
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study to Evaluate the Treatment of Both Near and Distance Vision in a Simultaneous Laser Procedure
Status: COMPLETED
Conditions: Myopia|Hyperopia|Presbyopia|Refractive Error
Interventions: PROCEDURE: Supracor
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Evaluate SIIPL qHPV Vaccine (CERVAVAC®) in Women Living With HIV Aged 15-25 Years
Status: NOT_YET_RECRUITING
Conditions: Human Papillomavirus Infection
Interventions: BIOLOGICAL: Cervavac as three dose regimen|BIOLOGICAL: Cervavac as two dose regimen|BIOLOGICAL: Gardasil as three dose regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of Acetaminophen in Postoperative Pain Management of Infants
Status: COMPLETED
Conditions: Analgesic|Enhanced Recovery After Surgery|Postoperative Pain|Infant ALL|Acetaminophen
Interventions: DRUG: Acetaminophen|DRUG: Sterilized water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Preventive Skin Analgesia With Lidocaine Patch 5% for Controlling Post-thoracotomy Pain
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: DRUG: Lidocaine patch 5%|DRUG: Placebo patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prophylactic Use of Hydroxycobolamin in Vasoplegic Syndrome in Adult Patients Undergoing Cardiopulmonary Bypass
Status: COMPLETED
Conditions: Vasoplegic Syndrome
Interventions: DRUG: Hydroxycobalamin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Endoscopic Ultrasonography-guided Double Ethanol Lavage for Pancreatic Cysts: a Prospective Cohort Study
Status: UNKNOWN
Conditions: Pancreatic Mucinous-Cystic Neoplasm
Interventions: DRUG: Endoscopic ultrasonography-guided double ethanol lavage
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Can Vitamin D Supplementation Improve Hepatitis C Cure Rates
Status: COMPLETED
Conditions: Hepatitis C
Interventions: DRUG: Active Comparator: Vigantol Oil (Vitamin D3)|DRUG: Mygliol Oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Stent and Prothesis Bypass in Superficial Femoral Artery
Status: UNKNOWN
Conditions: Arterial Occlusive Diseases|Vascular Diseases
Interventions: DEVICE: stent|DEVICE: femoral-popliteal bypass with artificial blood vessel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety, Tolerability, PK, and PD Study of Once Weekly ISIS-FGFR4RX SC in Obese Patients
Status: COMPLETED
Conditions: Obesity
Interventions: DRUG: ISIS-FGFR4RX|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Chronic Pain in Women Who Have Undergone Surgery for Stage I, Stage II, or Stage III Breast Cancer
Status: UNKNOWN
Conditions: Breast Cancer|Pain|Perioperative/Postoperative Complications
Interventions: OTHER: questionnaire administration|PROCEDURE: assessment of therapy complications|PROCEDURE: psychosocial assessment and care|PROCEDURE: quality-of-life assessment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Test the Pharmacodynamic, Pharmacokinetic, Safety, and Tolerability of Padsevonil in Healthy Study Participants Receiving Either Ethanol or Cannabidiol
Status: TERMINATED
Conditions: Healthy Participants
Interventions: DRUG: Padsevonil|DRUG: Placebo (PSL)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Screening and Educating Emergency Department Attendees on Health-risk Behaviours
Status: RECRUITING
Conditions: Health-risk Behaviours|Non Communicable Diseases
Interventions: OTHER: theory of planned behaviour, foot-in-the-door technique, and self-determination theory intervention|OTHER: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Dose-response Relationship of Botullinum Toxin (DWP 450) for Finger Flexor Spasticity
Status: UNKNOWN
Conditions: Spasticity as Sequela of Stroke
Interventions: DRUG: Normal Saline 0.9% 1.2 ml|DRUG: Clostridium Botulinum Toxin Type A (Nabota, DWP 450) 15 U|DRUG: Clostridium Botulinum Toxin Type A (Nabota, DWP 450) 30 U|DRUG: Clostridium Botulinum Toxin Type A (Nabota, DWP 450) 50 U|DRUG: Clostridium Botulinum Toxin Type A (Nabota, DWP 450) 70 U
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Research Study Looking at How a Single Dose of the Medicine NNC0194-0499 Behaves in Chinese Men
Status: COMPLETED
Conditions: Non-alcoholic Fatty Liver Disease
Interventions: DRUG: NNC0194-0499|DRUG: NNC0194-0499|DRUG: NC0194-0499
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of EPA on Aerobic Performance, Muscle, and Quality of Life in Colorectal Cancer Surgery Patients
Status: UNKNOWN
Conditions: Colorectal Cancer
Interventions: OTHER: Placebo|DIETARY_SUPPLEMENT: Experimental: Nutritional Supplementation with EPA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Continuous Invasive Blood Pressure Monitoring on Postinduction Hypotension in Patients Having Major Surgery
Status: COMPLETED
Conditions: Blood Pressure|Perioperative Hypotension|Postinduction Hypotension
Interventions: DEVICE: Continuous invasive blood pressure monitoring|DEVICE: Intermittent non-invasive blood pressure monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Group Education & Lifestyle Modification's Impact on Weight Loss & Quality Life of Patients With OA
Status: UNKNOWN
Conditions: Obesity|Osteo Arthritis Knee|Osteoarthritis, Hip
Interventions: OTHER: Lifestyle and dietary modification program
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: HP Xenon-129 fMRI of Healthy Volunteers and Participants With Alzheimer's Disease
Status: RECRUITING
Conditions: Alzheimer Disease
Interventions: OTHER: Traditional Proton fMRI|OTHER: Hyperpolarized Xenon-129 fMRI|DRUG: Hyperpolarized Xenon-129|DEVICE: 1H-129Xe Dual-Tuned Quadrature Head Coil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Urethral Stricture: A Comparison Between Jugal or Labial Graft Urethroplasty
Status: COMPLETED
Conditions: Urethral Stricture
Interventions: PROCEDURE: Labial Graft|PROCEDURE: Jugal Graft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Oxytocin, Stress, Craving, Opioid Use Disorder
Status: COMPLETED
Conditions: Opioid Use Disorder
Interventions: DRUG: intranasal oxytocin, 40 IU, twice a day for 7 days
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Liposomal Bupivacaine Compared to Usual Care and Its Effects on Pain for Cardiac Surgery
Status: UNKNOWN
Conditions: Cardiothoracic Surgery
Interventions: DRUG: Liposomal bupivacaine|DRUG: 0.25% Bupivacaine with epinephrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Letrozole-stimulated Cycle Strategy Versus Artificial Cycle Strategy (LETSACT)
Status: RECRUITING
Conditions: Embryo Transfer|Irregular Menstruation|Letrozole|Hormone Replacement Therapy
Interventions: PROCEDURE: Letrozole-stimulated cycle strategy|PROCEDURE: Artificial cycle strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cardiac Dysfunction in Adolescents With Type 1 Diabetes: Contribution of Daily-life Glucoregulation and Impact on Cardiorespiratory Exercise Capacity
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: OTHER: Cardiac dysfunction in adolescents with type 1 diabetes
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: ZK 230211 in Postmenopausal Woman With Metastatic Breast Cancer
Status: COMPLETED
Conditions: Metastatic Breast Cancer
Interventions: DRUG: Lonaprisan (ZK 230211, BAY86-5044)|DRUG: Lonaprisan (ZK 230211, BAY86-5044)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase III Trial of BI 201335 (Faldaprevir) in Treatment Naive (TN) and Relapser Hepatitis C Virus (HCV)-Human Immunodeficiency Virus (HIV) Coinfected Patients (STARTverso 4)
Status: COMPLETED
Conditions: Hepatitis C, Chronic
Interventions: DRUG: PegIFN/RBV|DRUG: PegIFN/RBV|DRUG: BI201335|DRUG: BI201335 24W|DRUG: PegIFN/RBV|DRUG: Bi 201335
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Role of Endogenous Glucagon-like Peptide 1 (GLP-1) in Type 2 Diabetes Mellitus (T2DM)
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: exendin(9-39)amide|DRUG: saline|OTHER: duodenal meal|OTHER: duodenal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Minimally Invasive Surgery: Using Natural Orifice Translumenal Endoscopic Surgery (NOTES)
Status: UNKNOWN
Conditions: Appendicitis|Cholelithiasis
Interventions: PROCEDURE: Transgastric Appendectomy|PROCEDURE: Transgastric Cholecystectomy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Capsaicin in Digital Osteoarthritis Versus Control
Status: NOT_YET_RECRUITING
Conditions: Osteoarthritis Hand|Neuropathic Pain
Interventions: DRUG: Capsaicin 179 Mg Cutaneous Patch|DRUG: Capsaicine low dose 0.04 %
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Peripheral Nerve Stimulation(PNS) for Subacromial Impingement Syndrome(SIS)
Status: COMPLETED
Conditions: Shoulder Pain|Shoulder Impingement Syndrome|Shoulder Tendinitis|Shoulder Bursitis|Pain, Shoulder
Interventions: DEVICE: Contracting Producing Peripheral Nerve Stimulation|DEVICE: Non Contracting Producing Peripheral Nerve Stimulation|OTHER: Physical Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Investigate the Effect of Rocatinlimab (AMG 451) on the Pharmacokinetics of Multiple Cytochrome P450 (CYP450) Substrates in Participants With Moderate to Severe Atopic Dermatitis
Status: ACTIVE_NOT_RECRUITING
Conditions: Atopic Dermatitis
Interventions: DIETARY_SUPPLEMENT: Caffeine|DRUG: Metoprolol|DRUG: Midazolam|DRUG: Warfarin|DIETARY_SUPPLEMENT: Vitamin K|DRUG: Omeprazole|DRUG: Rocatinlimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of C-CAR066 in Subjects With r/r B Cell Lymphoma Who Received CD19 CAR-T Therapy
Status: COMPLETED
Conditions: B Cell Lymphoma
Interventions: BIOLOGICAL: CD20-directed CAR-T cells with CliniMACS Prodigy® system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evexomostat Plus PI3K or AKT Inhibitor and Fulvestrant in Women With a PI3K Alteration and HR+/Her2- Breast Cancer
Status: RECRUITING
Conditions: HR+/HER2-negative Breast Cancer|Metastatic Breast Cancer
Interventions: DRUG: Evexomostat
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of Endothelial Function on Central and Peripheral Causes Of Exercise Impairment in Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: BEHAVIORAL: Exercise program|DRUG: Ascorbic Acid (Vitamin C)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH