pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Oral Paracetamol Premedication Effect on Maternal Pain in Amniocentesis
Status: UNKNOWN
Conditions: Amniocentesis
Interventions: DRUG: Paracetamol|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: E-monitoring of PULMonary Function in Patients With Duchenne Muscular Dystrophy at Home"
Status: RECRUITING
Conditions: Duchenne Muscular Dystrophy (DMD)
Interventions: DEVICE: AioCare spirometer|OTHER: telerehabiliation of the respiratory system
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Omeprazole on Pharmacokinetics of SHR2554 in Healthy Subjects
Status: COMPLETED
Conditions: Malignant Tumor
Interventions: DRUG: SHR2554 tablet dosing|DRUG: Omeprazole tablet dosing
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: LSH Silicone Hydrogel Soft Hydrophilic Contact Lens for Daily Wear
Status: COMPLETED
Conditions: Myopia
Interventions: DEVICE: Lagado LSH (mangofilcon A) Soft (hydrophilic) Contact Lens|DEVICE: Benz 3GX (hioxifilcon B) Soft (hydrophilic) Contact Lens
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Systemic Safety of Netarsudil 0.01%, 0.02%, 0.04% Relative to Placebo in Subjects With Open-angle Glaucoma or Ocular Hypertension in Japan
Status: COMPLETED
Conditions: Open Angle Glaucoma|Ocular Hypertension
Interventions: DRUG: Netarsudil Ophthalmic Solution 0.01%|DRUG: Netarsudil Ophthalmic Solution 0.02%|DRUG: Netarsudil Ophthalmic Solution 0.04%|OTHER: Netarsudil Ophthalmic Solution Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: RVA Breathes: A Richmond City Collaboration to Reduce Pediatric Asthma Disparities
Status: COMPLETED
Conditions: Asthma
Interventions: BEHAVIORAL: School|BEHAVIORAL: Asthma education|BEHAVIORAL: Home environmental remediation|BEHAVIORAL: Informational mail
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: First-In-Human (FIH) Trial Evaluating the Safety and Tolerability of Single and Multiple Ascending Oral Doses of IRL757 in Healthy Volunteers
Status: RECRUITING
Conditions: Not Determined
Interventions: DRUG: IRL757|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Temozolomide, Thalidomide, and Lomustine in Treating Patients With Unresectable Stage III or Stage IV Melanoma
Status: COMPLETED
Conditions: Intraocular Melanoma|Melanoma (Skin)
Interventions: DRUG: lomustine|DRUG: temozolomide|DRUG: thalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dopaminergic Modulation of Brain Activation Using Simultaneous PET/Pharmacological MRI
Status: COMPLETED
Conditions: Normal Physiology
Interventions: DRUG: Methylphenidate Pill|DRUG: Oral Placebo|DRUG: Intravenous Placebo|DRUG: Intravenous methylphenidate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Fusionless Treatment of Idiopathic Scoliosis With the SCOLI-TETHER System During The Growth Period
Status: TERMINATED
Conditions: Adolescent Idiopathic Scoliosis|Juvenile Idiopathic Scoliosis
Interventions: DEVICE: Anterior Vertebral Body Tethering
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Children's Forearm Shaft Fractures With Biodegradable Intramedullary Nailing, Compared With Elastic Stable Intramedullary Nailing
Status: COMPLETED
Conditions: Fractures, Bone|Injury Arm
Interventions: PROCEDURE: Biodegradable Intramedullary Nailing (BIN)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study for Detection of PSMA-Low CRPC-NE Tumors With Fluciclovine PET/CT
Status: RECRUITING
Conditions: Advanced Prostate Cancer|Metastatic Prostate Cancer|Metastatic Prostate Neuroendocrine Carcinoma
Interventions: DRUG: 18F-fluciclovine|DEVICE: PET/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Use of Adhesion Molecule Loaded Hydrogel With Minimally Invasive Surgical Technique in Treatment of Periodontal Intrabony Defect
Status: COMPLETED
Conditions: Periodontitis
Interventions: DRUG: RGD Peptide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Tissue Kallikrein Preventing the Restenosis After Stenting of Symptomatic MCA Atherosclerotic Stenosis
Status: UNKNOWN
Conditions: Cerebrovascular Disease
Interventions: DRUG: tissue kallikrein
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: 18F-Fluorocholine (18F-FCho) to Distinguish Necrosis From Recurrence in Brain Metastases
Status: COMPLETED
Conditions: Brain Metastases
Interventions: PROCEDURE: 18F-FCH PET Scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Immunogenicity of Yellow Fever Vaccine in a Pediatric Population Vaccinated at 12-23 Months of Age in Argentina
Status: ENROLLING_BY_INVITATION
Conditions: Yellow Fever
Interventions: BIOLOGICAL: Serological study after yellow fever vaccination
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Cognitive Training With and Without tDCS to Improve Cognition in HIV
Status: TERMINATED
Conditions: HIV|Mild Neurocognitive Disorder
Interventions: DEVICE: Transcranial direct current stimulation|PROCEDURE: Cognitive training|DEVICE: Sham transcranial direct current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Assessment of a Combined Strategy of SMC + Nutrients Supplementation to Tackle Malaria and Malnutrition
Status: UNKNOWN
Conditions: Malaria|Malnutrition, Child
Interventions: DRUG: AQSP Administration|DIETARY_SUPPLEMENT: Supplementation with Plumpy'Doz|DIETARY_SUPPLEMENT: Supplementation with Vitamin A|DIETARY_SUPPLEMENT: Supplementation with Zinc
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparative Effectiveness of Split-Dose Colonoscopy Bowel Preparation Regimens
Status: ACTIVE_NOT_RECRUITING
Conditions: Colorectal Cancer
Interventions: DRUG: Miralax-Gatorade Prep|DRUG: Golytely
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Shoulder Anterior Capsular Block and Interscalene Brachial Plexus Block for Shoulder Arthroscopy
Status: RECRUITING
Conditions: Shoulder Arthroscopy|Interscalene Brachial Plexus Block|Shoulder Anterior Capsular Block|Rotator Cuff Rupture
Interventions: PROCEDURE: Interscalene brachial plexus block|PROCEDURE: Shoulder anterior capsular block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phase 2 Study of Ipilimumab in Children and Adolescents (12 to < 18 Years) With Previously Treated or Untreated, Unresectable Stage III or Stage lV Malignant Melanoma
Status: TERMINATED
Conditions: Malignant Melanoma
Interventions: BIOLOGICAL: Ipilimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sorafenib Maintenance for Prophylaxis of Leukemia Relapse in Allo-HSCT Recipients With FLT3 Negative Acute Leukemia
Status: UNKNOWN
Conditions: Acute Leukemia|Relapse|Hematopoietic Stem Cell Transplantation
Interventions: DRUG: Sorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Drug-Drug Interaction (DDI) Study of ALXN2050 in Healthy Adult Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: ALXN2050|DRUG: Cyclosporine|DRUG: Tacrolimus|DRUG: MMF
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect of GnRH Agonist Administered in the Luteal Phase on ART Cycle Outcomes
Status: UNKNOWN
Conditions: Infertility
Interventions: DRUG: Leuprolide acetate|DRUG: vaginal progesterone|DRUG: 4 mg oral estradiol valerate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Role of Activated Charcoal in Decreasing Blood Urea, Creatinine and Phosphorous
Status: UNKNOWN
Conditions: Chronic Kidney Disease stage3
Interventions: DRUG: Activated charcoal|DIETARY_SUPPLEMENT: Dry seeds
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Omega 3 Fatty Acid Treatment for Pediatric Musculoskeletal Health
Status: WITHDRAWN
Conditions: Esophageal Atresia
Interventions: DRUG: Omegaven|DRUG: Intralipid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acupuncture/Moxibustion (Acu/Moxa) for Distal Symmetric Peripheral Neuropathy (DSP) in HIV
Status: COMPLETED
Conditions: Peripheral Neuropathy|HIV|AIDS|HIV Infections
Interventions: OTHER: Acupuncture / Moxibustion|OTHER: Acupuncture/Moxibustion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pembrolizumab + N-803 Alone or in Combination With PD-L1 t-haNK Cells for Resectable Head and Neck Squamous Cell Carcinoma
Status: NOT_YET_RECRUITING
Conditions: Stage II Squamous Cell Carcinoma of the Head and Neck|Stage III Squamous Cell Carcinoma of the Head and Neck|Stage IV Squamous Cell Carcinoma of the Head and Neck
Interventions: DRUG: N-803|DRUG: pembrolizumab|BIOLOGICAL: PD-L1 t-haNK cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Skilled Nursing Facility at Home Trial
Status: NOT_YET_RECRUITING
Conditions: Skilled Nursing Facility|Rehabilitation|Home Based Care
Interventions: OTHER: Sub-Acute Rehab at Home
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Support Person Intervention to Promote a Smoking Helpline Among Under Resourced Smokers
Status: COMPLETED
Conditions: Tobacco Cessation
Interventions: BEHAVIORAL: Telephone counseling 1 session|BEHAVIORAL: Mobile texting|BEHAVIORAL: Health incentive
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Role of GLP-1 in Hyperinsulinemic Hypoglycemia Post-bariatric Surgery
Status: UNKNOWN
Conditions: Hypoglycemia
Interventions: DRUG: Exendin (9-39)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Immune Response Elicited by Concomitant Administration of Oral Typhoid Fever (Vivotif®) and Cholera (Dukoral®) Vaccines
Status: RECRUITING
Conditions: Vaccine-Preventable Diseases|Typhoid Fever|Cholera
Interventions: BIOLOGICAL: Oral typhoid fever vaccine|BIOLOGICAL: Oral cholera vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Clinical Evaluation Of Alvimopan (SB767905) On Constipation And Related Symptoms Associated With Opioid
Status: TERMINATED
Conditions: Cancer|Constipation
Interventions: DRUG: alvimopan|DRUG: Placebo|DRUG: Alvimopan 0.5 mg/day|DRUG: Alvimopan 1 mg/day
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pembrolizumab and Oral Metronomic Cyclophosphamide in Patients With Chest Wall Breast Cancer
Status: NOT_YET_RECRUITING
Conditions: Breast Cancer|Chest Wall Tumor
Interventions: DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of TQB2450 in Combination With Intensity-modulated Radiotherapy in Patients With Inoperable Locally Recurrent Nasopharyngeal Carcinoma
Status: UNKNOWN
Conditions: Nasopharyngeal Carcinoma
Interventions: DRUG: TQB2450|RADIATION: Intensity modulated radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nivolumab, Fluorouracil, and Interferon Alpha 2B for the Treatment of Unresectable Fibrolamellar Cancer
Status: SUSPENDED
Conditions: Stage III Hepatocellular Carcinoma AJCC v8|Stage IIIA Hepatocellular Carcinoma AJCC v8|Stage IIIB Hepatocellular Carcinoma AJCC v8|Stage IV Hepatocellular Carcinoma AJCC v8|Stage IVA Hepatocellular Carcinoma AJCC v8|Stage IVB Hepatocellular Carcinoma AJCC v8|Unresectable Fibrolamellar Carcinoma
Interventions: DRUG: Fluorouracil|BIOLOGICAL: Nivolumab|BIOLOGICAL: Recombinant Interferon Alpha 2b-like Protein
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Varlilumab and Atezolizumab in Patients With Advanced Cancer
Status: TERMINATED
Conditions: Carcinoma, Renal Cell|Kidney Diseases|Kidney Neoplasms|Urogenital Neoplasms|Urologic Diseases|Urologic Neoplasms|Neoplasms by Histologic Type|Neoplasms|Clear-cell Metastatic Renal Cell Carcinoma|Melanoma|Triple Negative Breast Cancer|Bladder Cancer|Head and Neck Cancer|Non-small Cell Lung Cancer
Interventions: DRUG: Combination of Varlilumab and Atezolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral Changes With Caloric and no Caloric Sweeteners
Status: NOT_YET_RECRUITING
Conditions: pH|Microbiome|Dental Plaque
Interventions: DRUG: Stevioside
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study to Evaluate Safety, Tolerability and Pharmacokinetics of CS060304 in Healthy and Elevated LDL-C Subjects
Status: NOT_YET_RECRUITING
Conditions: MASH
Interventions: DRUG: CS060304
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Nintedanib Co-administered With Sildenafil in Idiopathic Pulmonary Fibrosis Patients With Advanced Lung Function Impairment
Status: COMPLETED
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: DRUG: Nintedanib|DRUG: Placebo|DRUG: Sildenafil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Octreotide Acetate in Microspheres in Patients With Diabetic Retinopathy
Status: COMPLETED
Conditions: Diabetic Retinopathy
Interventions: DRUG: Octreotide Acetate in Microspheres|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Duvelisib in Combination With Rituximab or Obinutuzumab in Subjects With Previously Untreated CD20+ Follicular Lymphoma (CONTEMPO)
Status: TERMINATED
Conditions: CD20+ Follicular Lymphoma
Interventions: DRUG: Duvelisib|DRUG: Rituximab|DRUG: Obinutuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I Study of Safety and Pharmacokinetics of Volitinib in Combination With Gefitinib in EGFR(+) NSCLC
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: Volitinib|DRUG: gefitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SHR- 1210 Combined With Paclitaxel (Albumin Bound) and Gemcitabine as First-line Therapy in Patients With Metastatic Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Cancer Stage IV
Interventions: DRUG: Biological: SHR-1210 Drug: Gemcitabine Drug:Paclitaxel-albumin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Respiratory Measurement of Volume Change Using Accelerometer, Thermographic Camera Electrical Impedance Tomography and Motion Correlation Analysis Using Mattress Sensor in Healthy Individuals
Status: UNKNOWN
Conditions: Healthy Adult
Interventions: DEVICE: accelometer|DEVICE: thermographic camera|DEVICE: Electrical Impedance Tomography|DEVICE: Mattress Sensor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Intranasal Dexmedetomidine VS Oral Chloral Hydrate for Rescue Sedation During Magnetic Resonance Imaging
Status: COMPLETED
Conditions: Administration Related Reaction|Failed Moderate Sedation During Procedure|Chloral Hydrate Adverse Reaction
Interventions: DRUG: chloral hydrate Group|DRUG: low dose dexmedetomidine group|DRUG: high dose dexmedetomidine group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose:
Clinical trial: Eylea and Lucentis for Macular Edema in Branch Retinal Vein Occlusion
Status: UNKNOWN
Conditions: Branch Retinal Vein Occlusion With Macular Edema
Interventions: DRUG: Aflibercept Injection [Eylea]|DRUG: Ranibizumab Injection [Lucentis]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Prospective, Multicenter Study to Evaluate the JensClip Transcatheter Valve Repair System
Status: NOT_YET_RECRUITING
Conditions: Degenerative Mitral Valve Disease|Mitral Valve Regurgitation
Interventions: DEVICE: JensClip transcatheter valve repair system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of OnabotulinumtoxinA (BOTOX®) for Urinary Incontinence Due to Neurogenic Detrusor Overactivity in Pediatric Patients
Status: COMPLETED
Conditions: Urinary Incontinence
Interventions: BIOLOGICAL: OnabotulinumtoxinA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Effects of Milk Thistle Extract With Vitamin-E in Hemodialysis Patients
Status: COMPLETED
Conditions: Hemodialysis|End Stage Renal Disease
Interventions: DRUG: Milk Thistle extract|DRUG: vit E|DRUG: vit E + Milk Thistle extract
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Web-Based Stem Cell Transplant Support System or Standard Care in Young Patients Undergoing Stem Cell Transplant and Their Families
Status: COMPLETED
Conditions: Chronic Myeloproliferative Disorders|Leukemia|Lymphoma|Myelodysplastic Syndromes|Myelodysplastic/Myeloproliferative Neoplasms|Neuroblastoma|Ovarian Cancer|Psychosocial Effects of Cancer and Its Treatment|Sarcoma
Interventions: OTHER: educational intervention|OTHER: informational intervention|OTHER: internet-based intervention|OTHER: questionnaire administration|OTHER: study of socioeconomic and demographic variables|OTHER: survey administration|PROCEDURE: psychosocial assessment and care|PROCEDURE: quality-of-life assessment|PROCEDURE: standard follow-up care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: |Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Geriatric Assessment and Promotores (GAP) Pilot Feasibility Study
Status: RECRUITING
Conditions: Breast Cancer|Colorectal Cancer|Prostate Cancer
Interventions: BEHAVIORAL: Geriatric Assessment and Promotora Coaching
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Identifying and Caring for Individuals With Inherited Cancer Syndrome
Status: RECRUITING
Conditions: BRCA1/2-Associated Hereditary Breast and Ovarian Cancer Syndrome|Breast Ductal Carcinoma In Situ|Hematopoietic and Lymphoid System Neoplasm|Hereditary Neoplastic Syndrome|Lynch Syndrome|Malignant Solid Neoplasm
Interventions: PROCEDURE: Biospecimen Collection|OTHER: Genetic Counseling|OTHER: Genetic Testing|OTHER: Survey Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Study to Assess Safety, Feasibility, and Preliminary Efficacy of the Apreo Implant for Severe Emphysema
Status: RECRUITING
Conditions: Emphysema or COPD
Interventions: DEVICE: Apreo Implant Group
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Maintenance of Efficacy of Extended-Release Guanfacine HCl in Children and Adolescents With Attention-deficit/Hyperactivity Disorder (ADHD)
Status: COMPLETED
Conditions: Attention-deficit/Hyperactivity Disorder
Interventions: DRUG: Extended-release Guanfacine Hydrochloride|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Impact of Noradrenaline on Ventriculo-arterial Coupling and Central Cardiovascular Energy Delivery
Status: COMPLETED
Conditions: Heart Diseases
Interventions: PROCEDURE: Noradrenalin|PROCEDURE: Noradrenalin|PROCEDURE: Noradrenalin|PROCEDURE: Noradrenalin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Depsipeptide to Treat Patients With Cutaneous T-Cell Lymphoma and Peripheral T-Cell Lymphoma
Status: COMPLETED
Conditions: Cutaneous T Cell Lymphoma|Peripheral T Cell Lymphoma
Interventions: DRUG: Romidepsin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Varenicline Tartrate With Telephone-Based Counseling and/or Internet-Based Counseling in Helping Adults Stop Smoking
Status: COMPLETED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: BEHAVIORAL: smoking cessation intervention|DRUG: varenicline|OTHER: counseling intervention|OTHER: internet-based intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety and Tolerability of Glatiramer Acetate
Status: COMPLETED
Conditions: Relapsing-Remitting Multiple Sclerosis
Interventions: DRUG: GA 20 mg/mL|DRUG: GA 40 mg/mL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Anlotinib With Pembrolizumab in Adults With Programmed Cell Death-Ligand 1 (PD-L1)-Positive Treatment-naïve Non-small Cell Lung Cancer
Status: UNKNOWN
Conditions: NSCLC
Interventions: DRUG: Anlotinib, oral capsule|BIOLOGICAL: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Genolair in Two Dosage Forms (Solution and Lyophilisate) and Xolair® in Healthy Volunteers
Status: COMPLETED
Conditions: Allergic Asthma
Interventions: BIOLOGICAL: Genolair, solution for subcutaneous administration, 150 mg|BIOLOGICAL: Genolair, lyophilisate for the preparation of solution for subcutaneous administration|BIOLOGICAL: Xolair®, solution for subcutaneous administration, 150 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Rosuvastatin Effect on Telomere-telomerase System in ACS
Status: UNKNOWN
Conditions: Telomere Shortening|Telomere Length, Mean Leukocyte|22q Telomere Deletion Syndrome
Interventions: DRUG: rosuvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety of Co-immunization With Cecolin and Hecolin
Status: UNKNOWN
Conditions: Human Papilloma Virus Infection Type 16|Human Papilloma Virus Infection Type 18|Hepatitis E Virus Infection
Interventions: BIOLOGICAL: Cecolin|BIOLOGICAL: Hecolin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy Plus Biological Therapy Followed By Peripheral Stem Cell Transplantation in Treating Patients With Hematologic Cancer
Status: COMPLETED
Conditions: Leukemia|Lymphoma|Multiple Myeloma and Plasma Cell Neoplasm|Myelodysplastic Syndromes
Interventions: BIOLOGICAL: anti-thymocyte globulin|DRUG: cyclophosphamide|DRUG: fludarabine phosphate|PROCEDURE: peripheral blood stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of 3D Magnetic Resonance Spirometry : Comparison to Spirometry in Healthy Subjects and Patients With Asthma and COPD
Status: NOT_YET_RECRUITING
Conditions: Asthma|COPD
Interventions: DIAGNOSTIC_TEST: 1. Standard spirometry|DIAGNOSTIC_TEST: 2. 3D dynamic lung MRI at UTE in prone and supine positions|DRUG: 3. Reversibility test with salbutamol|DIAGNOSTIC_TEST: 4. 3D dynamic lung MRI at UTE in supine and prone position
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Safety Study of AP23573 in Patients With Advanced, Refractory or Recurrent Malignancies (8669-013)(COMPLETED)
Status: COMPLETED
Conditions: Tumors|Lymphoma|Multiple Myeloma
Interventions: DRUG: ridaforolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Developmental and Augmented Intervention for Facilitating Expressive Language
Status: COMPLETED
Conditions: Joint Engagement + Enhanced Milieu Training|Joint Engagement + Enhanced Milieu Training+Augmentative Communication (AAC)
Interventions: BEHAVIORAL: JAE Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Studying the Hedonic and Homeostatic Regulation of Food Intake Using Functional MRI
Status: RECRUITING
Conditions: Healthy
Interventions: OTHER: Functional Magnetic Resonance Imaging (pCASL-MRI)|OTHER: Intragastric Balloon|OTHER: Elemental Meal|OTHER: Hedonic Meal
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Fluor Varnish With Silver Nanoparticles for Dental Remineralization in Patients With Trisomy 21
Status: UNKNOWN
Conditions: Down Syndrome
Interventions: DRUG: Fluor varnish|DRUG: Fluor varnish with nanoparticles
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Study to Determine if Olmesartan Medoxomil Has the Potential to Benefit the Cardiovascular System in Terms of Arterial Protection
Status: COMPLETED
Conditions: Metabolic Syndrome|Hypertension
Interventions: DRUG: olmesartan medoxomil|DRUG: placebo|DRUG: olmesartan medoxomil|DRUG: olmesartan medoxomil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety Study of A New Chromatographically Purified Vero Cell Rabies Vaccine With ID Regimen and ERIG
Status: COMPLETED
Conditions: Rabies
Interventions: BIOLOGICAL: SPEEDA and TRCS SPEEDA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effects of Post-exercise Protein Supplementation in Young Athletes
Status: COMPLETED
Conditions: Fatigue|Inflammation|Bone Resorption
Interventions: DIETARY_SUPPLEMENT: Experimental:Whey protein|DIETARY_SUPPLEMENT: Active Comparator: Isoenergetic control - Carbohydrate|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of 72-Hour Infusion of ON 01910.Na in Patients With MDS or AML
Status: COMPLETED
Conditions: Myelodysplastic Syndrome|Acute Myeloid Leukemia
Interventions: DRUG: ON 01910.Na
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prader-Willi Syndrome Body Composition
Status: COMPLETED
Conditions: Prader Labhart Willi Syndrome|Body Weight Changes|Sarcopenia
Interventions: OTHER: Therapeutic elastic band resistance training
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy and Radiation Therapy Plus Surgery in Treating Patients With Advanced Cancer of the Pancreas
Status: COMPLETED
Conditions: Stage IVA Pancreatic Cancer|Stage III Pancreatic Cancer|Adenocarcinoma of the Pancreas
Interventions: DRUG: fluorouracil|DRUG: gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Effect of Head and Gaze Position on Soft Toric Contact Lens Performance
Status: COMPLETED
Conditions: Astigmatism|Myopia
Interventions: DEVICE: senofilcon A|DEVICE: etafilcon A|DEVICE: nelfilcon A|DEVICE: Filcon II 3|DEVICE: Filcon II 3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Capnography During Upper GI Endoscopy
Status: COMPLETED
Conditions: Capnography as an Adjunct to Standard Monitoring During Midazolam and Propofol Sedation for Interventional Upper GI Endoscopy
Interventions: DEVICE: Capnography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety Study of Metronidazole, Nystatin and Dexamethasone Combination Therapy in Bacterial and Fungal Vaginal Infections
Status: UNKNOWN
Conditions: Bacterial Vaginosis|Fungal Vaginal Infections
Interventions: DRUG: Association of metronidazole; nystatin and dexamethasone|DRUG: Flagyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I Trial to Evaluate the Safety and Immunogenicity of eOD-GT8 60mer Vaccine, Adjuvanted
Status: COMPLETED
Conditions: HIV/AIDS
Interventions: BIOLOGICAL: eOD-GT8 60mer + AS01B/ DPBS sucrose/IM|BIOLOGICAL: eOD-GT8 60mer + AS01B/ DPBS sucrose/IM|BIOLOGICAL: DPBS Sucrose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of TQB2450 Injection Combined With Chemotherapy ± Anlotinib Hydrochloride Capsules for Advanced Endometrial Cancer or Sarcoma of Uterus.
Status: RECRUITING
Conditions: Advanced Endometrial Cancer|Sarcoma of Uterus
Interventions: DRUG: TQB2450 injection|DRUG: Anlotinib Hydrochloride Capsule|DRUG: Carboplatin Injection|DRUG: Paclitaxel Injection|DRUG: Doxorubicin Hydrochloride Injection|DRUG: Gemcitabine Hydrochloride Injection|DRUG: Docetaxel injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of PT003, PT005, and PT001 in Subjects With Moderate to Very Severe Chronic Obstructive Pulmonary Disease (COPD); (PINNACLE 1)
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: GFF MDI|DRUG: GP MDI|DRUG: FF MDI|DRUG: Open-label tiotropium bromide inhalation powder (Spiriva® Handihaler®)|DRUG: Placebo MDI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial to Evaluate the Effect of Vitamin D Supplementation in Patients With Chronic Urticaria
Status: UNKNOWN
Conditions: Urticaria|Vitamin D Deficiency
Interventions: DRUG: Vit D
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Levels of Pain and Discomfort Associated With Two Techniques of Corticotomy
Status: COMPLETED
Conditions: Class II Division 1 Malocclusion
Interventions: PROCEDURE: Traditional corticotomy|PROCEDURE: Flapless corticotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 1b Study to Evaluate ATP128, VSV-GP128 and BI 754091, in Patients With Stage IV Colorectal Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Colorectal Cancer|MSS|Stage IV Colon Cancer|Stage IV Rectal Cancer|Metastatic Colorectal Cancer|Liver Metastasis Colon Cancer
Interventions: DRUG: ATP128|DRUG: BI 754091|DRUG: VSV-GP128
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intrathecal Pemetrexed for Leptomeningeal Metastasis From Lung Adenocarcinoma That Progressed After Osimertinib.
Status: NOT_YET_RECRUITING
Conditions: Leptomeningeal Metastasis
Interventions: DRUG: Pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Laryngeal Injuries After Anesthesia Induction With Three Different Sevoflurane Concentrations (Without Muscle Relaxant)
Status: COMPLETED
Conditions: Other Specified Injuries of Vocal Cord, Sequela
Interventions: DRUG: sevoflurane 1,0|DRUG: sevoflurane 1,2|DRUG: sevoflurane 1,4
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Transcatheter Self-expandable Valve Implantation for the Treatment of Severe Native Aortic Regurgitation
Status: RECRUITING
Conditions: Aortic Valve Disease
Interventions: DEVICE: Transcatheter Aortic Valve Implantation|DRUG: Medical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Local Made and Imported Porous Polyethylene Orbital Implant for Enucleation in Thailand
Status: COMPLETED
Conditions: Phthisis Bulbi
Interventions: DEVICE: 3DP|DEVICE: Medpor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transplantoux Health Evaluation Study
Status: RECRUITING
Conditions: Quality of Life
Interventions: OTHER: Home-based indiviualized exercise training program|OTHER: Supervised group training sessions|OTHER: Climb of the Mont Ventoux
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Erythropoietin Therapy in Patients With Chronic Renal Failure: A Study of Time Dependent Activity
Status: COMPLETED
Conditions: Hemodialysis|Chronic Renal Failure|Anemia
Interventions: DRUG: r-HuEPO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Vitamin E+Selenium on Kidney Function in Controlled Hypotension
Status: UNKNOWN
Conditions: Acute Kidney Injury
Interventions: DRUG: vitamin E +Selenium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: 25gr. Glucomedics vs 25gr. Zusto
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: DIETARY_SUPPLEMENT: Zusto|DIETARY_SUPPLEMENT: Glucomedics®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Efficacy Study of Gevokizumab to Treat Active Non-infectious Uveitis
Status: TERMINATED
Conditions: Uveitis
Interventions: DRUG: Placebo|DRUG: Dose 1 gevokizumab|DRUG: Dose 2 gevokizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Slowed Carboplatin Infusion for Ovarian Cancer Patients Receiving Carboplatin Re-Treatment
Status: TERMINATED
Conditions: Recurrent Ovarian Cancer|Platinum Sensitive Ovarian Cancer
Interventions: DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy and Safety Study of PGA (Poly-gamma Glutamic Acid) for Cervical Intraepithelial Neoplasia
Status: COMPLETED
Conditions: Cervical Intraepithelial Neoplasia
Interventions: DRUG: Poly-gamma Glutamic Acid|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Intravaginal Prasterone on Symptoms of VVA in Women Under Treatment With an Aromatase Inhibitor for Breast Cancer
Status: WITHDRAWN
Conditions: Vaginal Atrophy in Breast Cancer Patients
Interventions: DRUG: Placebo|DRUG: Prasterone (DHEA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Performance of CONTOUR NEXT® and CONTOUR PLUS ELITE® BGMS in Neonates Using Capillary Blood Samples
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: DEVICE: Contour Next and Contour Plus Elite BGMS testing of neonatal blood
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Decision Support for Detection of Chronic Kidney Disease in Type II Diabetes Mellitus
Status: RECRUITING
Conditions: Chronic Kidney Diseases|Type2Diabetes
Interventions: OTHER: Alert-based computerized decision support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effects of Unilateral and Bilateral Mirror Therapy on Upper Extremity Function of Stroke at Acute Stage.
Status: RECRUITING
Conditions: Stroke, Acute
Interventions: OTHER: unilateral and bilateral mirror therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: DetectIon of Severe Sepsis In PATients With Neurological haemorrhagE (The DISSIPATE Study)
Status: RECRUITING
Conditions: Sepsis|Hemorrhage Brain
Interventions: DIAGNOSTIC_TEST: APTT CWA (Activated partial thromboplastin time clot waveform analysis), Procalcitonin and Serological/Inflammatory markers (KL-6, SPA, MIG, Presepsin)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Dose Ranging Study of Indacaterol in Japanese Patients With Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Indacaterol 150 μg|DRUG: Indacaterol 300 μg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Food Effect and Relative Bioavailability Study of VC004 Capsules in Healthy Adult Subjects
Status: COMPLETED
Conditions: Locally Advanced or Metastatic Solid Tumor Harboring an NTRK Gene Fusion
Interventions: DRUG: High Dose VC004 Capsules|DRUG: Median Dose VC004 Capsules|DRUG: Low Dose VC004 Capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Midodrine Plus Albumin Versus Midodrine Alone to Prevent Cirrhosis Related Complications in Children With Cirrhosis and Ascites
Status: NOT_YET_RECRUITING
Conditions: Liver Cirrhosis
Interventions: DRUG: Midodrine|BIOLOGICAL: albumin|OTHER: Standard Medical Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Blood Levels of Abacavir in HIV Infected Adolescents
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Abacavir sulfate|DRUG: Abacavir sulfate, lamivudine, and zidovudine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Relaxation Response Mind-body Intervention in Patients With IBS and IBD
Status: COMPLETED
Conditions: Irritable Bowel Syndrome|Inflammatory Bowel Disease
Interventions: BEHAVIORAL: Relaxation Response Mind-Body Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Synergistic Effect of G-Eye Balloon for Behind the Folds Visualization With CADe (Discovery System) on Adenoma Detection Rate.
Status: RECRUITING
Conditions: Colorectal Polyp|Colonoscopy|Artificial Intelligence|Adenoma
Interventions: DEVICE: colonoscopy assisted by both balloon-Behind The Folds visualizing and Computer assisted detection (CADe)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Enhancing the Cardiovascular Safety of Hemodialysis Care (Dialysafe)
Status: ENROLLING_BY_INVITATION
Conditions: Kidney Failure|End Stage Renal Disease|Hypotension|Cardiovascular Diseases|Patient Safety
Interventions: BEHAVIORAL: Patient Activation|BEHAVIORAL: Provider Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Bone Marrow Transplantation of Patients in Remission Using Partially Matched Relative Donor
Status: COMPLETED
Conditions: Acute Myeloid Leukemia|Myelodysplastic Syndromes|Biphenotypic Leukemia|Acute Lymphocytic Leukemia|Chronic Myeloid Leukemia|Chronic Lymphocytic Leukemia|Plasma Cell Neoplasms|Lymphoma|Hodgkin's Disease|Aplastic Anemia
Interventions: RADIATION: Total Body Irradiation (TBI)|BIOLOGICAL: Donor Lymphocyte Infusion (DLI)|DRUG: Cyclophosphamide|DRUG: Mycophenolate Mofetil (MMF)|DRUG: Tacrolimus|DEVICE: Hematopoietic stem cell transplantation (HSCT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Clinical Study of UTAA09 Injection in the Treatment of Relapsed/Refractory Autoimmune Diseases
Status: RECRUITING
Conditions: Systemic Lupus Erythematosus|Idiopathic Inflammatory Myopathies|Systemic Sclerosis|IgG4 Related Disease|Primary Sjögren Syndrome
Interventions: BIOLOGICAL: T cell injection targeting CD19 chimeric antigen receptor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Pharmacokinetics of Mitoxantrone Hydrochloride Liposome Injection in Recurrent/Refractory Lymphoma Subjects
Status: COMPLETED
Conditions: Recurrent/Refractory Lymphoma
Interventions: DRUG: Mitoxantrone Hydrochloride Liposome Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Two Doses of Thylakoids on OGTT
Status: COMPLETED
Conditions: Glucose Intolerance
Interventions: DIETARY_SUPPLEMENT: Experimental: Thylakoids 5 g|DIETARY_SUPPLEMENT: Experimental: Thylakoids 10 g|OTHER: Placebo Comparator: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Randomized Phase II Study in Elderly Patients With Newly Diagnosed Multiple Myeloma
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: Bortezomib, Lenalidomide, Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diagnostic Accuracy of "Three Rings Vulvoscopy" for Detection of Vulvar Dermatosis
Status: COMPLETED
Conditions: Lichen Sclerosus|Lichen Planus|Lichen Simplex Chronicus|Vulvodynia
Interventions: DIAGNOSTIC_TEST: "Three Rings Vulvoscopy" (TRIV)|PROCEDURE: Histopathology
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC