pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Anecortave Acetate for Treatment of Steroid Induced Intraocular Pressure (IOP) Elevation
Status: COMPLETED
Conditions: Eye Diseases
Interventions: DRUG: Anecortave Acetate Sterile Suspension, 6 mg/mL|DRUG: Anecortave Acetate Suspension Depot, 30 mg/mL|DRUG: Anecortave Acetate Sterile Suspension, 60 mg/mL|OTHER: Anecortave Acetate Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Energy Dense Biscuits in Undernourished Women on Birth Weight of Their Neonates
Status: UNKNOWN
Conditions: Birth Weight
Interventions: DIETARY_SUPPLEMENT: Energy dense biscuits|OTHER: Wheat Flour, oil, iron & Folic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acute Effects of Coffee Beverage on Postprandial Inflammation and Oxidative Stress - A Pilot Study
Status: COMPLETED
Conditions: Overweight|Obese|Healthy
Interventions: DIETARY_SUPPLEMENT: Coffee|DIETARY_SUPPLEMENT: Water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of Birdshot Retine Choroidopathy Treatment by Either Steroid or Interferon alpha2a
Status: COMPLETED
Conditions: Birdshot Chorioretinopathy|Cystoid Macular Edema|Transient Partial Visual Loss
Interventions: DRUG: interferon alpha 2a|DRUG: prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stroke Volume Variation vs Central Venous Pressure Guidance Fluid Management in Endovascular Aortic Repair
Status: COMPLETED
Conditions: Postoperative Complications
Interventions: PROCEDURE: Fluid management protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Metabolic Health in Individuals With Spinal Cord Injury (SCI)
Status: COMPLETED
Conditions: Spinal Cord Injuries|Skeletal Muscle Atrophy|Metabolic Disease
Interventions: OTHER: Neuromuscular electrical stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Thrombolysis and Deferoxamine in Middle Cerebral Artery Occlusion
Status: COMPLETED
Conditions: Ischemic Stroke, Acute
Interventions: DRUG: Deferoxamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mononuclear Cells, Platelets and Zoledronic Acid for Preventing Collapse of the Femoral Head in Osteonecrosis
Status: UNKNOWN
Conditions: Osteonecrosis
Interventions: PROCEDURE: Control group|BIOLOGICAL: Mononuclear Cells|BIOLOGICAL: Platelets|DRUG: Zoledronic Acid|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Bariatric Surgery, Hormones, and Quality of Life
Status: COMPLETED
Conditions: Obesity|Hormone Disturbance|Quality of Life|Hyperandrogenism
Interventions: PROCEDURE: Laparoscopic gastric-bypass surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioavailability of Compounds From Different Bean Varieties in Healthy Individuals.
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: Navy Beans (cooked)|OTHER: Red Kidney Beans (cooked)|OTHER: Pinto Beans (cooked|OTHER: Black Beans (cooked)|OTHER: Lentils (cooked)|OTHER: White Rice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose:
Clinical trial: Raltegravir Use as Nonoccupational Postexposure Prophylaxis (NPEP) in Men Who Have Sex With Men
Status: COMPLETED
Conditions: HIV Prevention|HIV Infections
Interventions: DRUG: Raltegravir
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exploring Medically Perceived Benefits, Use and Interest in Psychedelics and Cannabinoids
Status: COMPLETED
Conditions: PTSD|Anxiety|Anxiety Disorders|Depression|Depressive Disorder|Psychological|Psychedelic Experiences|Psychedelic Drug Dependence
Interventions: DRUG: Cannabis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Buspirone, in Combination With Amantadine, for the Treatment of Levodopa-induced Dyskinesia
Status: TERMINATED
Conditions: Parkinson's Disease|Dyskinesias|Movement Disorders
Interventions: DRUG: Buspirone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Safety and Pharmacokinetics of CNTO 136 in Patients With Cutaneous Lupus Erythematosus and Systemic Lupus Erythematosus
Status: COMPLETED
Conditions: Lupus Erythematosus, Cutaneous|Lupus Erythematosus, Systemic
Interventions: DRUG: 1 mg/kg CNTO 136|DRUG: 4 mg/kg CNTO 136|DRUG: 10 mg/kg CNTO 136|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prostate Artery Embolization With Embosphere Microspheres Compared to TURP for Benign Prostatic Hyperplasia
Status: TERMINATED
Conditions: Benign Prostatic Hyperplasia
Interventions: DEVICE: Embosphere Microspheres|PROCEDURE: TURP
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Continuous Glucose Monitoring in Patients With ACS and Type 2 Diabetes in ICU
Status: TERMINATED
Conditions: Acute Coronary Syndrome|Type 2 Diabetes
Interventions: DEVICE: Control Glucose Monitoring System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Anti-inflammatory Topical Prednisolone, Nepafenac and Ketorolac in Intra-operative Mydriasis in Facetectomies
Status: UNKNOWN
Conditions: Cataract
Interventions: DRUG: prednisolone acetate 1%|DRUG: ketorolac tromethamine 0.4%|DRUG: nepafenac 0.1%|DRUG: methylcellulose 0.5%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Novel Brain Stimulation for Bimanual Motor Function and Control in Chronic Stroke
Status: COMPLETED
Conditions: Stroke
Interventions: DEVICE: Novel rTMS Approach|DEVICE: Sham rTMS Approach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II Trial of Anti-HER2 Treatment in HER2-enriched Early Breast Cancer Identified by PAM50 (HER2E-PAM, PAMILIA Study)
Status: RECRUITING
Conditions: HER2 Enriched Subtype Breast Cancer, Herzuma, PAM50 Study
Interventions: DRUG: Herzuma
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Botulinum Toxin Type A for the Treatment of Neurogenic Overactive Bladder
Status: TERMINATED
Conditions: Overactive Bladder
Interventions: BIOLOGICAL: botulinum toxin Type A|DRUG: Normal Saline (Placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Beneficial Effects of a Nasal Spray of Resveratrol in Children With Seasonal Allergic Rhinitis
Status: COMPLETED
Conditions: Seasonal Allergic Rhinitis
Interventions: DRUG: Resveratrol nasal spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Immunogenicity and Safety Study of a Third Vaccination With FSME-IMMUN 0.5 mL in Subjects Previously Vaccinated According to a Rapid Immunization Schedule (Follow-up to Study 225)
Status: COMPLETED
Conditions: Encephalitis, Tick-borne
Interventions: BIOLOGICAL: Formaldehyde inactivated, sucrose gradient purified TBE virus antigen, strain Neudörfl
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: EXerCise wEight Loss
Status: COMPLETED
Conditions: Overweight and Obesity
Interventions: BEHAVIORAL: Resistance exercise training + weight loss group|BEHAVIORAL: Weight loss only group (WL)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Metabolic Consequences of Moderate Weight Gain - Role of Dietary Fat Composition (LIPOGAIN)
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: Polyunsaturated fatty acid group|OTHER: Saturated fatty acid group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Drug-Drug Interaction Study of ENV-101 (Taladegib) on Nintedanib Pharmacokinetics in Healthy Subjects
Status: COMPLETED
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: DRUG: taladegib|DRUG: nintedanib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effect of Degranulation Needle With Different Diameters on the Rate Good Embryo in IVF
Status: UNKNOWN
Conditions: Embryo
Interventions: DEVICE: 140 microns denuding pipette|DEVICE: 150 microns denuding pipette
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Predictive Value of a Preliminary Swallowing Test Compared to Postoperative Nasofibroscopy to Identify Vocal Cord Paralysis After Pulmonary Resection
Status: UNKNOWN
Conditions: Adults Patients Undergoing Major Lung Resection in the Context of Lung Cancer
Interventions: DIAGNOSTIC_TEST: preliminary swallowing test
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Treatment of Chronic Central Serous Chorioretinopathy With Open-Label Anecortave Acetate
Status: COMPLETED
Conditions: Chronic Central Serous Chorioretinopathy
Interventions: DRUG: Anecortave Acetate Sterile suspension 15 mg|DRUG: Anecortave Acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Econazole Nitrate Foam 1% and Foam Vehicle in Subjects With Tinea Pedis
Status: COMPLETED
Conditions: Tinea Pedis|Athlete's Foot
Interventions: DRUG: Econazole Nitrate Foam 1%|DRUG: Vehicle Foam|DRUG: Econazole Nitrate Cream 1%|OTHER: Placebo Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Consuming a Mixture of Extracts and DHA on the Mild Cognitive Impairment
Status: RECRUITING
Conditions: Mild Cognitive Impairment
Interventions: DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: mixture of extracts and DHA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: MASTER I - Microvolt T Wave Alternans Testing for Risk Stratification of Post MI Patients
Status: COMPLETED
Conditions: Myocardial Infarction|Arrhythmia, Ventricular|Ischemic Cardiomyopathy
Interventions: PROCEDURE: T Wave Alternans Test
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Presence of Donor-Derived DNA in Semen Samples From Cancer Survivors Who Underwent Donor Stem Cell Transplant
Status: TERMINATED
Conditions: Cancer Survivor|Chronic Myeloproliferative Disorders|Leukemia|Lymphoma|Multiple Myeloma and Plasma Cell Neoplasm|Myelodysplastic Syndromes|Myelodysplastic/Myeloproliferative Neoplasms|Neuroblastoma|Testicular Germ Cell Tumor
Interventions: GENETIC: DNA analysis|GENETIC: polymerase chain reaction|OTHER: flow cytometry|OTHER: laboratory biomarker analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Facilitated Tucking Position and Reiki Efficacy in Orogastric Tube Insertion
Status: COMPLETED
Conditions: Premature|Feeding Behavior|Infant, Premature, Diseases
Interventions: OTHER: Facilitated Tucking Position|OTHER: Reiki
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study on The Safety of Administering Rituximab at A More Rapid Rate in Patients With Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: rituximab|DRUG: methotrexate|DRUG: methylprednisolone|DRUG: acetaminophen|DRUG: antihistamine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of ITF2357 on Mucosal Healing in Patients With Moderate-to-severe Active Crohn's Disease
Status: TERMINATED
Conditions: Crohn's Disease
Interventions: DRUG: ITF2357|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Angiotensin II and Chronic Inflammation in Persistent Microvascular Dysfunction Following Preeclampsia
Status: UNKNOWN
Conditions: Preeclampsia
Interventions: DRUG: Salsalate Oral Tablet|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Impact of Levagen+® Palmitoylethanolamide (PEA) in a Cross-Over Trial Examining Stress and Cognition in University Students
Status: COMPLETED
Conditions: Wellness, Psychological|Well-Being, Psychological
Interventions: DIETARY_SUPPLEMENT: Levagen+® Palmitoylethanolamide (PEA)|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of New Diagnostic Methods of Cardio-embolic Related (Atrial Fibrillation) Cerebral Infarction
Status: TERMINATED
Conditions: Stroke
Interventions: PROCEDURE: MRI|PROCEDURE: Abdominal scanner
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The EFFORT Trial and EFFORT Outcomes Sub-study (EFFORT-Outcomes)
Status: UNKNOWN
Conditions: Critical Illness|Malnutrition
Interventions: DIETARY_SUPPLEMENT: Usual Care|DIETARY_SUPPLEMENT: Higher Protein/Amino Acid Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Creation of an E-toileting Log Through Classification of the Physical Properties of Stool and Urine Using TrueLoo™
Status: COMPLETED
Conditions: Urinary Tract Infections|Infectious Diarrhea|Clostridium Difficile Infection|Gastrointestinal Disease|GastroIntestinal Bleeding
Interventions: DEVICE: TrueLoo™
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Correlations Between Oxidative Stress Biomarkers, h-FABP and Left Ventricular Dysfunction in Patients With Acute Myocardial Infarction Undergoing Primary PCI
Status: UNKNOWN
Conditions: STEMI|Oxidative Stress|Oxidative Stress Induction|Primary PCI|hFABP|Left Ventricular Dysfunction|BCM
Interventions: OTHER: Dosing Oxidative stress biomarkers & hFABP in STEMI pPCI patients
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study on Spermatogenesis in Male Renal Transplant Recipients Receiving Valganciclovir (Valcyte®) Versus Untreated Matched Controls
Status: COMPLETED
Conditions: Cytomegalovirus Infections
Interventions: DRUG: Valganciclovir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: OTHER
Clinical trial: Febuxostat Versus Allopurinol Control Trial in Subjects With Gout
Status: COMPLETED
Conditions: Gout
Interventions: DRUG: Febuxostat|DRUG: Febuxostat|DRUG: Allopurinol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Antenatal Thyrotropin-Releasing Hormone in Women in Premature Labor to Prevent Lung Disease in Preterm Infants
Status: COMPLETED
Conditions: Respiratory Distress Syndrome
Interventions: DRUG: thyrotropin-releasing hormone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Study in Healthy Men to Test How Different Doses of BI 3031185 Are Tolerated and How Food Influences the Amount of BI 3031185 in the Blood
Status: ACTIVE_NOT_RECRUITING
Conditions: Healthy
Interventions: DRUG: BI 3031185|DRUG: Placebo matching BI 3031185
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prognostic Factors for Surgical Management of Large Hypertensive Basal Ganglionic Haemorrhage
Status: NOT_YET_RECRUITING
Conditions: Basal Ganglionic Hemorrhage
Interventions: OTHER: Prognostic factors of surgical evacuation of basal ganglionic haemorrhage
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Chlorambucil in Metastatic PDAC Patients Bearing a Germ Line DNA Defects Repair Mutations (SALE Trial)
Status: ACTIVE_NOT_RECRUITING
Conditions: Pancreatic Ductal Adenocarcinoma
Interventions: DRUG: Chlorambucil, Oral, 2 Mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study That Will Evaluate Ketogenesis and Glucose-Dependent Insulin Secretion Methodologies in Healthy Male Subjects (MK-0000-159)(COMPLETED)
Status: COMPLETED
Conditions: Obesity
Interventions: DRUG: Oxyntomodulin (OXM)|DRUG: Comparator: Oxyntomodulin (OXM)|DRUG: Comparator: Placebo [ hemaccel-containing saline]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Antidepressant Effects of Nitrous Oxide
Status: RECRUITING
Conditions: Major Depressive Disorder|Treatment Resistant Depression
Interventions: DRUG: Nitrous oxide gas for inhalation|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Safety and Feasibility of OGX-011 in Combination With 2nd-line Chemotherapy in Patients With HRPC
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: custirsen (OGX-011)/mitoxantrone|DRUG: custirsen (OGX-011)/docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: DZHK TORCH-Plus is a Registry for Patients With Cardiomyopathies and Serves as Source for Cardiovascular Research Studies
Status: RECRUITING
Conditions: Non-ischemic Cardiomyopathy|DCM - Dilated Cardiomyopathy|HCM - Hypertrophic Cardiomyopathy|HOCM - Hypertrophic Obstructive Cardiomyopathy|Arrhythmogenic Right Ventricular Cardiomyopathy|Left Ventricular Noncompaction Cardiomyopathy|Amyloidosis|Inflammatory Cardiomyopathy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Metabolic Effects of Non-Nutritive Sweeteners
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: OTHER: Sucralose|OTHER: Aspartame|OTHER: Acesulfame-Potassium|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: E-health Brisk Walking in Older People With Cognitive Frailty
Status: NOT_YET_RECRUITING
Conditions: Cognitive Frailty
Interventions: BEHAVIORAL: E-health enhanced behavioural change intervention|BEHAVIORAL: Conventional behavioural change intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Applying Shear Wave Elastography for Adjunct Steroid on Tuberculous Lymphadenitis
Status: RECRUITING
Conditions: Tuberculous Lymphadenitis
Interventions: DRUG: Prednisolone|DRUG: standard anti-tuberculosis agents
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Τicagrelor Versus Prasugrel in Diabetic Patients: a Pharmacodynamic Study
Status: COMPLETED
Conditions: Coronary Artery Disease|Acute Coronary Syndrome
Interventions: DRUG: Prasugrel|DRUG: Ticagrelor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of AA4500 (XIAFLEX™, Proposed Name) in the Treatment of Advanced Dupuytren's Disease
Status: COMPLETED
Conditions: Advanced Dupuytren's Disease
Interventions: BIOLOGICAL: collagenase clostridium histolyticum
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stem Cells for Uremic Calciphylaxis Patients
Status: UNKNOWN
Conditions: Chronic Kidney Diseases|Calciphylaxis|Calcific Uremic Arteriolopathy|Treatment
Interventions: OTHER: Human amniotic mesenchymal stem cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Immune Checkpoint Inhibition and Novel IO Combinations in Early-stage Colon Cancer
Status: RECRUITING
Conditions: Colon Carcinoma
Interventions: DRUG: Nivolumab|DRUG: Ipilimumab|DRUG: Celecoxib 200mg|DRUG: BMS-986253|DRUG: BMS-986016
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: DIATOR-Diabetes Intervention With Atorvastatin
Status: TERMINATED
Conditions: Type 1 Diabetes
Interventions: DRUG: Atorvastatin|DRUG: atorvastatin matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Yoga as a Supportive Therapy for Patients With Hypertension
Status: COMPLETED
Conditions: Hypertension
Interventions: BEHAVIORAL: Yoga with Asana (yoga postures)|BEHAVIORAL: Yoga without Asana (yoga postures)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of 1592U89 in Combination With Protease Inhibitors in HIV-Infected Patients Who Have Never Taken Anti-HIV Drugs
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Indinavir sulfate|DRUG: Ritonavir|DRUG: Abacavir sulfate|DRUG: Amprenavir|DRUG: Nelfinavir mesylate|DRUG: Saquinavir
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: PD-1 Inhibitor Intraperitoneal Perfusion Combined With PRaG Therapy for Malignant Ascites
Status: UNKNOWN
Conditions: Malignant Ascites
Interventions: DRUG: Serplulimab|DRUG: Molgramostim|RADIATION: Hypofractionated radiotherapy/Sterotactic body radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Augmentation of Working Memory Training With Transcranial Direct Current Stimulation in Patients With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia|Cognitive Deficits
Interventions: DEVICE: active tDCS|DEVICE: sham tDCS|BEHAVIORAL: Adaptive working memory training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Optune Device - TT Field Plus Nivolumab and Ipilimumab for Melanoma With Brain Metastasis
Status: TERMINATED
Conditions: Melanoma With Brain Metastasis
Interventions: DEVICE: Optune|BIOLOGICAL: Nivolumab|BIOLOGICAL: Ipilimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Coronary Artery Bypass Graft (CABG) Patch Trial
Status: COMPLETED
Conditions: Arrhythmia|Cardiovascular Diseases|Coronary Disease|Death, Sudden, Cardiac|Heart Diseases|Myocardial Infarction|Myocardial Ischemia|Ventricular Arrhythmia
Interventions: DEVICE: defibrillators, implantable
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Low Dose Aspirin Alerts in High-Risk Pregnancies
Status: RECRUITING
Conditions: Preeclampsia|Aspirin|Clinical Decision Support Systems|Economics, Behavioral
Interventions: BEHAVIORAL: Electronic health record best practice alert
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Virus Specific Cytotoxic T-Lymphocytes (CTLs) for Refractory Cytomegalovirus (CMV)
Status: RECRUITING
Conditions: Cytomegalovirus Infections|Primary Immune Deficiency Disorder
Interventions: DRUG: viral specific cytotoxic t-lymphocytes
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neurogenic Inflammation in Peri-implant and Periodontal Diseases
Status: COMPLETED
Conditions: Neurogenic Inflammation|Periimplant Diseases|Periodontal Diseases|Gingival Crevicular Fluid|Periimplant Sulcular Fluid
Interventions: DIAGNOSTIC_TEST: gingival crevicular fluid (GCF) and peri-implant sulcular fluid(PISF) collection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study on Ultrapro vs Polypropylene: Early Results From a Multicentric Experience in Surgery for Hernia
Status: UNKNOWN
Conditions: Chronic Pain
Interventions: DEVICE: ULTRAPRO® meshes|DEVICE: "Prolene®" meshes|PROCEDURE: Detecting the mode of admission to hospital|PROCEDURE: Duration of surgery|PROCEDURE: Anesthesia volume and type used
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Lung Function Changes Following the Addition of Formoterol to Tiotropium in Patients With Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Formoterol twice daily|DRUG: Formoterol once daily|DRUG: Tiotropium once daily|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: AiDing Diuresis wIth Tolvaptan (ADD-IT)
Status: COMPLETED
Conditions: Cardiomyopathy|Congestive Heart Failure
Interventions: DRUG: Tolvaptan 30 mg + IV Diuretics|DRUG: Metolazone 5 mg + IV Diuretics|DRUG: 2.5 times the Diuretics Dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Assessing the Efficacy and Safety of Lodotra® Compared to Prednisone IR in Subjects Suffering From PMR
Status: TERMINATED
Conditions: Polymyalgia Rheumatica
Interventions: DRUG: Lodotra®|DRUG: Prednisone IR (immediate release)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Continuous Central Venous Oxygen Saturation Measurement as a Tool to Predict Hemodynamic Instability Related to Renal Replacement Therapy in Critically Ill Patients
Status: RECRUITING
Conditions: Acute Kidney Injury
Interventions: DEVICE: Fiber-optic probe CeVOX
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Nivolumab, Ipilimumab and OTSGC-A24 Therapeutic Peptide Vaccine in Gastric Cancer - a Combination Immunotherapy Phase Ib Study.
Status: UNKNOWN
Conditions: Gastric Cancer
Interventions: DRUG: OTSGC-A24|DRUG: Nivolumab|DRUG: Ipilimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prone Plank Exercises for Diastasis Rectus Abdominis in Postpartum Women
Status: RECRUITING
Conditions: Post Partum Women
Interventions: OTHER: Prone plank exercises|DEVICE: Electrical Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study of CC-220 to Treat Systemic Lupus Erythematosus.
Status: COMPLETED
Conditions: Systemic Lupus Erythematosus
Interventions: DRUG: CC-220|DRUG: CC-220|DRUG: CC-220|DRUG: CC-220|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Emotional and Cognitive Self-regulation, an EEG Study
Status: COMPLETED
Conditions: Complex Posttraumatic Stress Disorder (cPTSD)|Dissociative Disorder Not Otherwise Specified (DDNOS)|Dissociative Identity Disorder (DID)
Interventions: OTHER: therapeutic treatment (inpatient and outpatient setting)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Use of Remote Monitoring to Improve Patient-Reported Outcomes and Readmission Rates Following Radical Cystectomy
Status: NOT_YET_RECRUITING
Conditions: Bladder Cancer|Quality of Life
Interventions: DEVICE: provider monitoring and feedback to remote data|DEVICE: participant monitoring of remote data
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Total-Body Irradiation, Cyclophosphamide, and Stem Cell Transplantation in Treating Patients With Hematologic Cancer
Status: COMPLETED
Conditions: Leukemia|Lymphoma|Myelodysplastic Syndromes|Myelodysplastic/Myeloproliferative Diseases
Interventions: DRUG: cyclophosphamide|PROCEDURE: allogeneic bone marrow transplantation|PROCEDURE: peripheral blood stem cell transplantation|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial to Assess the Shedding,Immunogenicity, and Safety of FluMist Administered to Healthy Individuals 5-49 Years of Age
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: FluMist
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Physical Therapy of Dysphagia on Preventing Pneumonia in Acute Stroke Patients
Status: COMPLETED
Conditions: Stroke, Acute|Dysphagia|Pneumonia
Interventions: DIETARY_SUPPLEMENT: Dietary supplement|OTHER: Physical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effects of Normobaric Hypoxia During Exercise in Patients With Pulmonary Hypertension With/Without Sildenafil
Status: COMPLETED
Conditions: Hypertension, Pulmonary
Interventions: OTHER: Normobaric hypoxia (FiO2 15%)|OTHER: Placebo-ambient air (FiO2 21%)|OTHER: Normobaric hypoxia (FiO2 15%) under Sildenafil|OTHER: Placebo-ambient air (FiO2 21%) under Sildenafil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Influence of Ambient Temperature on Resting Energy Expenditure of Healthy Adults
Status: COMPLETED
Conditions: Resting Energy Expenditure
Interventions: OTHER: Respiratory analysis at cold temperature|OTHER: Respiratory analysis at room temperature|OTHER: Respiratory analysis at thermoneutral temperature|OTHER: Respiratory analysis at hot temperature
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety of Hormonal Contraceptives Therapies in Polycystic Ovary Syndrome (PCOS) Women
Status: COMPLETED
Conditions: Polycystic Ovary Syndrome
Interventions: DRUG: oral contraceptive|DRUG: Oral contraceptive plus spironolactone|DRUG: Oral contraceptive plus metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nebulized Ketamine to Nebulized Fentanyl for Treating Acute Painful Conditions in the ED
Status: RECRUITING
Conditions: Pain, Acute
Interventions: DRUG: Ketamine|DRUG: Fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Dapagliflozin on Intestinal Microbiota Composition and on the Metabolites Derived From the Intestinal Microbiota in Non-diabetic Chronic Renal Failure Patients
Status: RECRUITING
Conditions: Chronic Kidney Diseases
Interventions: DRUG: impact of Dapagliflozin on Intestinal Microbiota on chronic renal failure patients
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Narrow Band Imaging (NBI): A Novel Imaging Modality in Minimally Invasive
Status: COMPLETED
Conditions: Endometrial Cancer|Fallopian Tube Cancer|Ovarian Cancer|Peritoneal Cancer|Gastrointestinal Carcinoma|Pancreatic Carcinoma|Lung Cancer|Esophageal Carcinoma
Interventions: OTHER: Narrow Band Imaging (NBI)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: RO4929097and Bevacizumab in Treating Patients With Progressive or Recurrent Malignant Glioma
Status: TERMINATED
Conditions: Adult Anaplastic Astrocytoma|Adult Anaplastic Oligodendroglioma|Adult Giant Cell Glioblastoma|Adult Glioblastoma|Adult Gliosarcoma|Recurrent Adult Brain Tumor
Interventions: DRUG: gamma-secretase/Notch signalling pathway inhibitor RO4929097|BIOLOGICAL: bevacizumab|OTHER: laboratory biomarker analysis|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Efficacy of Asystems' Complete Calm Supplementation on Sleep Quality and Duration, Anxiety, and Stress
Status: COMPLETED
Conditions: Sleep|Stress|Anxiety
Interventions: DIETARY_SUPPLEMENT: De-Stress Gummies
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Immunologic Response After Pandemic Influenza A (H1N1) Vaccine in Onco- Hematologic Patients
Status: COMPLETED
Conditions: Lymphoma|Multiple Myeloma|Myeloproliferative Disease
Interventions: BIOLOGICAL: Reassortant vaccine virus NYMC X-179A (New York Medical College, New York) derived form the A/california/7/2009 (H1N1) virus
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Fecal Microbiota Transplantation for the Treatment of Non-Alcoholic Steatohepatitis
Status: UNKNOWN
Conditions: Non-Alcoholic Fatty Liver Disease|Non Alcoholic Steatohepatitis
Interventions: OTHER: Fecal Microbiota Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Extension Study in a Cohort of Adult Patients With COVID-19 Infection
Status: COMPLETED
Conditions: COVID-19 Infection
Interventions: DRUG: Plitidepsin 1.5 mg / day|DRUG: Plitidepsin 2.0 mg / day|DRUG: Plitidepsin 2.5 mg / day
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Is Pre-anaesthetic Teleconsultation a Safe Alternative to Traditional Pre-anaesthetic Consultation?
Status: COMPLETED
Conditions: Anesthesia
Interventions: OTHER: preanaesthetic teleconsultation|OTHER: preanaesthetic classical physical consultation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Bintrafusp Alfa in High Mobility Group AT-Hook 2 (HMGA2) Expressing Triple Negative Breast Cancer
Status: TERMINATED
Conditions: Triple Negative Breast Neoplasms
Interventions: DRUG: Bintrafusp alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Potential Predictors of Adherence by Investigating a Representative Cohort of Multiple Sclerosis (MS) Patients in Germany Treated With Betaferon
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DRUG: Interferon beta-1b (Betaferon, BAY86-5046)|DEVICE: Betaconnect Autoinjector
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Trial Evaluating the Efficacy and Safety of HC-1119 Soft Capsules in Patients With Metastatic Castration-Resistant Prostate Cancer (mCRPC).
Status: RECRUITING
Conditions: mCRPC
Interventions: DRUG: HC-1119|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of PEGPH20 With Cisplatin (CIS) and Gemcitabine (GEM); PEGPH20 With Atezolizumab (ATEZO), CIS, and GEM; and CIS and GEM Alone in Participants With Previously Untreated, Unresectable, Locally Advanced, or Metastatic Intrahepatic and Extrahepatic Cholangiocarcinoma and Gallbladder Adenocarcinoma
Status: TERMINATED
Conditions: Cholangiocarcinoma Non-resectable|Cholangiocarcinoma, Intrahepatic|Cholangiocarcinoma, Extrahepatic|Gallbladder Adenocarcinoma
Interventions: DRUG: PEGPH20|DRUG: CIS|DRUG: GEM|DRUG: Atezolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial of Tai Chi Intervention for Youngsters With Visual Impairments
Status: ACTIVE_NOT_RECRUITING
Conditions: Visual Impairment and Blindness (Excl Colour Blindness)
Interventions: BEHAVIORAL: Moderate-intensity aerobic exercise refers to rhythmic and long-lasting exercise with increased heart rate, slight sweating and slight wheezing.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: CD4-specific CAR T Cells (CD4 CAR T Cells) for Relapsed/Refractory T Cell Malignancies
Status: UNKNOWN
Conditions: T Cell Lymphoma in Relapse|Refractory T-Cell Lymphoma
Interventions: BIOLOGICAL: CD4 CAR T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lifestyle Intervention Feasibility for Arrhythmia and Symptoms With Intermittent Fasting (LIFE AS IF)
Status: COMPLETED
Conditions: Obesity|Morbid Obesity|Diabetes Mellitus, Type 2|Atrial Fibrillation
Interventions: BEHAVIORAL: Intermittent Fasting
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Controlled Study of Kneehab XP for Patients Undergoing Total Knee Replacement
Status: COMPLETED
Conditions: Total Knee Replacement
Interventions: DEVICE: Kneehab XP|DEVICE: Quadriceps TENS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: AXER-204 in Participants With Chronic Spinal Cord Injury
Status: COMPLETED
Conditions: Chronic Spinal Cord Injury
Interventions: DRUG: AXER-204|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomised Controlled Trial of Self-help Mindfulness-based Cognitive Therapy for Health Workers
Status: COMPLETED
Conditions: Psychological Stress
Interventions: BEHAVIORAL: The self-help book: Williams, M. & Penman, D. (2011). Mindfulness: A practical guide to finding peace in a frantic world. London: Piatkus.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Granulocyte Colony Stimulating Factor Four Week Plus N-Acetyl Cysteine in Severe Alcoholic Hepatitis
Status: COMPLETED
Conditions: Alcoholic Hepatitis
Interventions: DRUG: Standard Medical Therapy|DRUG: G-CSF|DRUG: G-CSF and NAC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MOSE to Improve the Diagnostic Accuracy During EUS-guided FNA Using a 19-gauge Needle for Solid Lesions
Status: COMPLETED
Conditions: Solid Tumor
Interventions: PROCEDURE: Macroscopic on-site evaluation|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Bacteriostatic Saline as a Local Anesthetic in Minor Eyelid Procedures
Status: COMPLETED
Conditions: Eyelid Tumor|Eyelid Bump|Eyelid Deformity|Eyelid Abscess|Eyelid Boil|Eyelid Papilloma|Anesthesia, Local|Ophthalmology
Interventions: DRUG: 0.9% Bacteriostatic Local Anesthetic Injection|DRUG: 1% Lidocaine with 1:100,000 epinephrine Local Anesthetic Injection|PROCEDURE: Eyelid Lesion Removal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Serious Asthma Outcome Study With Mometasone Furoate/Formoterol Versus Mometasone Furoate in Asthmatics 12 Years and Over (P06241)
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Mometasone Furoate/Formoterol MDI 100/5 mcg|DRUG: Mometasone Furoate/Formoterol MDI 200/5 mcg|DRUG: Mometasone Furoate MDI 100 mcg|DRUG: Mometasone Furoate MDI 200 mcg|DRUG: Albuterol 90 mcg /salbutamol 100 mcg HFA MDI|DRUG: Prednisone/prednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Emervel for the Correction of Lower Face Wrinkles & Folds
Status: COMPLETED
Conditions: Nasolabial Folds|Marionette Lines|Wrinkles
Interventions: DEVICE: Emervel Classic and/or Deep Treatment Group
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Pharmacology and Hemodynamics of Dexmedetomidine in Children With Congenital Heart Disease
Status: COMPLETED
Conditions: Cardiac Transplant|Patent Ductus Arterious|Atrial Septal Defect|Bidirectional Cavopulmonary Anastomosis
Interventions: DRUG: Dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Efficacy and Safety Study of Bortezomib in Participants Previously Treated for Multiple Myeloma With Limited Kidney Function
Status: TERMINATED
Conditions: Multiple Myeloma
Interventions: DRUG: Dexamethasone|DRUG: Bortezomib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MK-0646 Insulin Growth Factor 1 Receptor Antibody in Stage IIIb or IV Metastatic Non-Squamous Lung Cancer
Status: COMPLETED
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: Arm A: Pemetrexed Cisplatin|DRUG: Arm B Pemetrexed, Cisplatin and MK-0646
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diagnosis and Physiopathology of Insulin Allergy
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1|Diabetes Mellitus, Type 2|Hypersensitivity|Immediate Hypersensitivity|Allergy
Interventions: PROCEDURE: Allergy tests
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Randomized, Prospective, Double-Blind Study Comparing Fluconazole With Placebo for Primary and Secondary Prophylaxis of Mucosal Candidiasis in HIV-Infected Women
Status: COMPLETED
Conditions: Candidiasis|Candidiasis, Esophageal|HIV Infections
Interventions: DRUG: Fluconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Definition of the Status of the Human Lung Stem Cell Niches ex Vivo in Tissue Biopsies Performed in Patients With Emphysema and Interstitial Fibrosis
Status: UNKNOWN
Conditions: Lung Diseases, Interstitial
Interventions: OTHER: analysis of the number of stem cell niches
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Spinal Anesthesia and General Anesthesia for Pyloromyotomy - Surgical Outcomes a Comparison Retrospective Study
Status: UNKNOWN
Conditions: Hypertrophic Pyloric Stenosis|Spinal Anesthesia|General Anesthesia
Interventions: DEVICE: Spinal anesthesia|DEVICE: General anesthesia
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Impact of Pediatric Acute Renal Injury in Severe Sepsis in Young Adults
Status: WITHDRAWN
Conditions: Acute Kidney Injury|Chronic Kidney Disease|Hypertension
Interventions: DRUG: Iodohippurate|PROCEDURE: 24 hour ambulatory Blood Pressure|PROCEDURE: Peripheral Arterial Tonometry|PROCEDURE: Pulse Wave Velocity|DRUG: Gadolinium
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p