pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Efficacy of Narrative Exposure Therapy (NET) in Treating Women After Human Trafficking or Forced Prostitution
Status: COMPLETED
Conditions: Posttraumatic Stress Disorder|Depression|Dissociation
Interventions: BEHAVIORAL: Narrative Exposure Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Lifestyle Exercise and Diet Trial (LEAD) 2.0
Status: RECRUITING
Conditions: Subjective Cognitive Decline
Interventions: BEHAVIORAL: EX|BEHAVIORAL: DIET|BEHAVIORAL: STRETCH|BEHAVIORAL: ED
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Changes in Inflammatory State in Asian Americans Changing From Traditional Asian Diets to American Diet - a Pilot Study
Status: COMPLETED
Conditions: Diabetes|Insulin Resistance|Inflammation|Cardiovascular Disease|Periodontal Disease
Interventions: BEHAVIORAL: 2 groups of population responding to 2 types of diets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Multidom Remote Monitoring of Patient With Advanced Pancreatic Cancer Treated With Florinox Using the PiCaDo Plateform
Status: RECRUITING
Conditions: Pancreas Cancer
Interventions: DEVICE: Picado system internet platform and connected objects
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Moxifloxacin AF Ophthalmic Solution for Treatment of Bacterial Conjunctivitis
Status: COMPLETED
Conditions: Bacterial Conjunctivitis
Interventions: DRUG: Moxifloxacin Alternative Formulation (AF) Ophthalmic Solution 0.5%|OTHER: Moxifloxacin AF Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bevacizumab and BKM-120 in Patients With Metastatic Renal Cell Carcinoma
Status: COMPLETED
Conditions: Renal Cell Carcinoma
Interventions: DRUG: BKM-120 Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Web-based Transition Education to Enhance Transition Readiness
Status: ACTIVE_NOT_RECRUITING
Conditions: Congenital Heart Disease|Transition|Pediatric Congenital Heart Disease
Interventions: BEHAVIORAL: Web-based Educational Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Phase 1 Study to Evaluate the Pharmacokinetics and Tolerability of Oral Azacitidine in Japanese Patients With Myelodysplastic Syndromes
Status: COMPLETED
Conditions: Myelodysplastic Syndromes
Interventions: DRUG: Oral azacitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 0.075% Capsaicin Lotion for the Treatment of Painful Diabetic Neuropathy
Status: COMPLETED
Conditions: Peripheral Diabetic Neuropathy
Interventions: DRUG: 0.075% Capsaicin Lotion|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigating Bioequivalence Between Single-dose Liraglutide Administered Subcutaneously With Two Different Pen-injectors
Status: COMPLETED
Conditions: Metabolism and Nutrition Disorder|Obesity
Interventions: DRUG: liraglutide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Correlation of Peak Tidal Inspiratory Flow Measured Before and After Extubation in Adult Patients With Hypoxemia
Status: TERMINATED
Conditions: Hypoxemic Respiratory Failure
Interventions: OTHER: HFNC flow set at patient peak tidal inspiratory flow|OTHER: HFNC flow set at 1.33 times of patient peak tidal inspiratory flow|OTHER: HFNC flow set at 1.67 times of patient peak tidal inspiratory flow|OTHER: HFNC flow set at 2 times of patient peak tidal inspiratory flow
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radiofrequency-Based Debridement vs. Mechanical Debridement for the Treatment of Articular Cartilage Lesions
Status: TERMINATED
Conditions: Articular Cartilage Disorder of Knee
Interventions: DEVICE: Radiofrequency-Based Debridement|DEVICE: Mechanical Debridement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Computational Cognitive Training To Boost Reward Responsiveness In Anhedonic Patients
Status: COMPLETED
Conditions: Anhedonia|Depression
Interventions: BEHAVIORAL: High Reward - High Variance|BEHAVIORAL: High Reward - Low Variance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Repeat Transplantation for Relapsed or Refractory Hematologic Malignancies Following Prior Transplantation
Status: TERMINATED
Conditions: Acute Lymphoblastic Leukemia (ALL)|Acute Myeloid Leukemia (AML)|Myeloid Sarcoma|Chronic Myelogenous Leukemia (CML)|Juvenile Myelomonocytic Leukemia (JMML)|Myelodysplastic Syndrome (MDS)|Non-Hodgkin Lymphoma (NHL)
Interventions: DRUG: Cyclophosphamide|DRUG: Fludarabine|BIOLOGICAL: G-CSF|BIOLOGICAL: Interleukin-2|DRUG: Melphalan|DRUG: Thiotepa|DRUG: Rituximab|BIOLOGICAL: Natural killer cell therapy|BIOLOGICAL: T-cell depleted HPC transplant|BIOLOGICAL: CD45RA-depleted HPC transplant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anticoagulant Plus Antiplatelet Therapy Following Iliac Vein Stenting
Status: RECRUITING
Conditions: Deep Vein Thrombosis|Iliac Vein Thrombosis|Iliac Vein Obstruction|Iliac Vein Stenosis|Iliac Vein Compression Syndrome
Interventions: DRUG: Rivaroxaban|DRUG: Aspirin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Different Skin-to-skin Contact Techniques: Sustained Diagonal Flexion vs. Traditional
Status: RECRUITING
Conditions: Skin-to-skin|Preterm Birth
Interventions: PROCEDURE: Sustained Diagonal Flexion positioning|PROCEDURE: Traditional prone position
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effect of Rifampin on the Single-dose Pharmacokinetics (PK) of BMS-986141 in Healthy Subjects
Status: COMPLETED
Conditions: Atherothrombotic Diseases
Interventions: DRUG: BMS 986141|DRUG: Rifampin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: To Demonstrate the Relative Bioavailability of Divalproex Sodium 500 mg Delayed Release Tablets Under Fed Conditions
Status: COMPLETED
Conditions: Epilepsy|Bipolar Disorder
Interventions: DRUG: Divalproex Sodium 500 mg DR Tablets (Sandoz Inc., USA)|DRUG: Depakote 500 mg DR Tablets (Abbott Laboratories, USA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Verkes Borderline Study: The Effect of Quetiapine on Borderline Personality Disordered Patients
Status: COMPLETED
Conditions: Borderline Personality Disorder
Interventions: DRUG: Quetiapine fumarate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Short-term Study of Combination Treatment of Escitalopram and Gaboxadol in Major Depressive Disorder
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: Escitalopram placebo|DRUG: Gaboxadol placebo|DRUG: Escitalopram 20 mg|DRUG: Gaboxadol 5 mg|DRUG: Gaboxadol 10 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Exemestane As Treatment In Adjuvant For Post-Menopausal Patients With Non-Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Neoplasms
Interventions: DRUG: exemestane|DRUG: tamoxifen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: LAparoscopic Preventive PRErectal Mesh
Status: RECRUITING
Conditions: Urogenital Prolapse
Interventions: PROCEDURE: Single-Anterior-Mesh, SAM|PROCEDURE: Double-Mesh, DM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Blood Management During ECMO for Cardiac Support
Status: COMPLETED
Conditions: Death, Sudden, Cardiac|HEART ARREST|Shock, Cardiogenic|Arrhythmias, Cardiac|Hemorrhage|Venous Thrombosis|Embolism|Blood Transfusion|Disseminated Intravascular Coagulation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Sedation With Remimazolam During Spinal Anesthesia
Status: COMPLETED
Conditions: Sedation|Spinal Anesthesia
Interventions: DRUG: Remimazolam|DRUG: Dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Minoxidil Dose Response Study in Females Identified Through IVD Testing as Non-Responders to 5% Topical Minoxidil
Status: WITHDRAWN
Conditions: Female Pattern Hair Loss|Androgenetic Alopecia
Interventions: DRUG: 5% Topical Minoxidil Solution|DRUG: 15% Topical Minoxidil Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Effects of Conscious Abdominal Contraction and Closed Kinetic Chain Exercises
Status: COMPLETED
Conditions: Subacromial Impingement
Interventions: OTHER: Closed kinetic chain exercises|OTHER: Abdominal contraction exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: First-In-Human Study of BBT-401-1S Following Single and Multiple Ascending Doses in Healthy Volunteers
Status: COMPLETED
Conditions: Ulcerative Colitis
Interventions: DRUG: BBT-401-1S, Single dose|DRUG: BBT-401-1S, Multiple doses|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Using the Visualization for Lifestyle Change in Patients at Risk of Cardiovascular Diseases
Status: ACTIVE_NOT_RECRUITING
Conditions: Cardiovascular Diseases|Coronary Artery Disease|Heart Diseases|Coronary Heart Disease|Visual Analytics|Continuous Glucose Monitoring|CGM|Lifestyle|Behaviour Change
Interventions: DEVICE: CGM|DIAGNOSTIC_TEST: Visualization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Monocentric STUDY, Randomised Double Blinded (Healthy Subjects, or Transversal (Patients With Gitelman Syndrome)
Status: COMPLETED
Conditions: Gitelman Syndrome|Potassium Depletion
Interventions: DIETARY_SUPPLEMENT: Potassium depletion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Glucocorticosteroid Treatment in Acute Unilateral Vestibulopathy (Vestibular Neuronitis)
Status: COMPLETED
Conditions: Acute Peripheral Vestibulopathy
Interventions: DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Intracutaneous Sterile Water and Diclofenac Sodium Injections in Renal Colic
Status: NOT_YET_RECRUITING
Conditions: Renal Colic
Interventions: DRUG: Sterile Water Injection|DRUG: Diclofenac Sodium injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Maternal Psychological Implications of Covid-19 Pandemic and Possible Effect on Anaesthetic Management.
Status: UNKNOWN
Conditions: Covid-19|Maternal Psychological Distress|Anesthesia
Interventions: OTHER: PHQ-9 Depression Scale|OTHER: GAD-7 General anxiety disorder scale|OTHER: 38-questions questionnaire
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effectiveness and Safety of Combination of Nebivolol and Zofenopril in Hypertensive patIents Versus Each Monotherapy
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Zofenopril 30 mg|DRUG: Nebivolol 5 mg|DRUG: Zofenopril 30 mg + Nebivolol 5 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Changes of Body Composition, Glucolipid Metabolism and Bone Metabolism in Obese Children After Weight Loss
Status: COMPLETED
Conditions: Obesity, Childhood|Vitamin D Deficiency
Interventions: BEHAVIORAL: aerobic exercise and appropriate caloric control
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Follow-up Evaluation for Safety in Subjects Who Participated in a Phase 1 Study With BMS-986094 (INX-08189)
Status: COMPLETED
Conditions: Healthy|Hepatitis C
Interventions: DRUG: BMS-986094/INX-08189|DRUG: Placebo matching BMS-986094/INX-08189
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of HNC664 in Healthy Subjects to Evaluate the Safety, Tolerability, and Pharmacokinetics
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: HNC664 capsules Single dose|DRUG: HNC664 placebos Single dose|DRUG: HNC664 capsules FED
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Motesanib (AMG 706) in Combination With Paclitaxel and Carboplatin for Advanced Non-Squamous Non-Small Cell Lung Cancer
Status: TERMINATED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: Motesanib|DRUG: Placebo|DRUG: Paclitaxel|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hepatic Artery Infusion With Oxaliplatin
Status: WITHDRAWN
Conditions: Colorectal Cancer|Metastasis|Liver Cancer
Interventions: DRUG: Oxaliplatin (via HAI)|DRUG: 5 Fluorouracil (systemic)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Different Head Positions During Endotracheal Intubation on Postoperative Sore Throat
Status: RECRUITING
Conditions: Endotracheal Intubation|General Anesthesia
Interventions: OTHER: the head in the "sniffing position "
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy of the Minimally Invasive Bentall Procedure Via a Small Right Intercostal Incision in Patients With Aortic Root Lesions
Status: RECRUITING
Conditions: Aortic Dissection|Aortic Root Aneurysm|Minimally Invasive Surgical Procedures
Interventions: PROCEDURE: Minimally invasive Bentall procedure
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Bare Metal Stents and Drug Eluting Stents in Patients Who Underwent Blood Transfusion
Status: COMPLETED
Conditions: Erythrocyte Transfusion|Percutaneous Coronary Intervention|Revascularization
Interventions: DEVICE: Stent, red blood cell transfusion
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Salivary Parameters in Patients Receiving CoQ10 and Vitamin E Supplementation
Status: ENROLLING_BY_INVITATION
Conditions: Periodontal Diseases
Interventions: DRUG: Receive 30 mg of Coq10
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Analgesic Efficacy of Adding SCB With Low Concentration Bupivacaine Combined With Dexamethasone on Pain After TKA
Status: UNKNOWN
Conditions: Total Knee Arthroplasty|Adductor Canal Block|Sciatic Nerve Block
Interventions: DRUG: bupivacaine and dexamethasone|DRUG: bupivacaine and lidocaine|DEVICE: Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Food BE Study Metformin Hydrochloride ER Tablets 500 mg and Glucophage XR 500 mg
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Metformin Hydrochloride ER Tablets 500 mg|DRUG: Glucophage XR 500 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effects of Internet-based Storytelling Programs in Reducing Mental Illness Stigma With Mediation by Interactivity and Stigma Content
Status: COMPLETED
Conditions: COMBO Condition|STIGMA Condition|INTERACT Condition|CONTROL Condition
Interventions: BEHAVIORAL: Internet-based storytelling programs with interactivity and stigma content|BEHAVIORAL: Internet-based storytelling programs with stigma content only|BEHAVIORAL: Internet-based storytelling programs with interactivity only|BEHAVIORAL: Internet-based storytelling programs with no interactivity and no stigma content
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: To Assess the Protective Effect of the Fixed Drug Combination of Disodium Cromoglycate Plus Reproterol
Status: COMPLETED
Conditions: Asthma, Exercise-Induced
Interventions: DRUG: Combination DSCG and Reproterol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial of Recombinant COVID-19 Bivalent (XBB+Prototype) Protein Vaccine (Sf9 Cell) in Booster Vaccination
Status: NOT_YET_RECRUITING
Conditions: COVID-19
Interventions: BIOLOGICAL: Recombinant COVID-19 Bivalent (XBB+Prototype) Protein Vaccine (Sf9 Cell) (WSK-V101C)|BIOLOGICAL: Recombinant COVID-19 vaccine(Sf9 Cell) (WSK-V101)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study on Relationship Between Resected Normal Liver Parenchymal Volume（RNLV）and Post-Hepatectomy Liver Failure (PHLF)
Status: ACTIVE_NOT_RECRUITING
Conditions: Liver Failure
Interventions: DIAGNOSTIC_TEST: the different definitions of PHLF according to 50-50 criteria and ISGLS criteria
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Internet-delivered Attention Training for Obsessive-Compulsive Disorder
Status: COMPLETED
Conditions: Obsessive-Compulsive Disorder
Interventions: BEHAVIORAL: Attention Training Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combined Y-90 Selective Internal Radiation Therapy (Y-90 SIRT) and Stereotactic Body Radiation Therapy (SBRT) in Hepatic Malignancy.
Status: RECRUITING
Conditions: Liver Malignancy
Interventions: DRUG: Yttrium-90|DEVICE: Selective Internal Radiation Therapy|RADIATION: Stereotactic Body Radiation Therapy|DIAGNOSTIC_TEST: PET/CT|DEVICE: Therasphere
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of Naloxone on Ticagrelor Pharmacokinetics and Pharmacodynamics in Patients With Unstable Angina Pectoris on Concomitant Treatment With Morphine
Status: COMPLETED
Conditions: Unstable Angina Pectoris
Interventions: DRUG: Crushed ticagrelor followed by morphine|DRUG: Crushed ticagrelor, morphine,naloxone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Investigate the Effect of Tart Montmorency Cherry Juice (Prunus Cerasus) on Vascular Function.
Status: COMPLETED
Conditions: Hypertension
Interventions: DIETARY_SUPPLEMENT: 60mL tart Montmorency cherry juice|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Point-of-Care Follow-Up With Primary Care After Emergency Department Discharge
Status: COMPLETED
Conditions: Conditions Influencing Health Status
Interventions: BEHAVIORAL: ZocDoc Assistance|BEHAVIORAL: ZocDoc Information
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Efficacy and Safety of Sirolimus in LAM
Status: COMPLETED
Conditions: Lymphangioleiomyomatosis
Interventions: DRUG: Sirolimus|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: APOLLO: The Study of an Investigational Drug, Patisiran (ALN-TTR02), for the Treatment of Transthyretin (TTR)-Mediated Amyloidosis
Status: COMPLETED
Conditions: TTR-mediated Amyloidosis|Amyloidosis, Hereditary|Amyloid Neuropathies, Familial|Familial Amyloid Polyneuropathies|Amyloid Neuropathies|Amyloidosis, Hereditary, Transthyretin-Related
Interventions: DRUG: patisiran (ALN-TTR02)|DRUG: Sterile Normal Saline (0.9% NaCl)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Safety and Immunogenicity of a COVID-19 Vaccine in People Living With HIV at Risk for SARS-CoV-2 (COVID-19)
Status: COMPLETED
Conditions: SARS-CoV-2 Infection
Interventions: BIOLOGICAL: NVX-CoV2373
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy of Different Dose Levels of Pasireotide in Patients With de Novo, Persistent or Recurrent Cushing's Disease
Status: COMPLETED
Conditions: Cushing's Disease
Interventions: DRUG: Pasireotide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Continuing or Discontinuing ACE/ARBs in Patients With Chronic Kidney Disease Undergoing Coronary Angiography
Status: RECRUITING
Conditions: Contrast-induced Nephropathy|Chronic Kidney Diseases|Ischemic Heart Disease
Interventions: OTHER: Continue ACEI or ARBs ( Enalapril , Ramipril , Valsartan , Candesartan, Losartan )|OTHER: Hold ACEI or ARBs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Glycemic Control After Antenatal Corticosteroids in Women With Pregestational and Gestational Diabetes
Status: RECRUITING
Conditions: Diabetes Mellitus, Type 2|Preterm Birth|Pregnancy, High Risk|Diabetes, Gestational
Interventions: DRUG: Sliding Scale Insulin|DRUG: Up-Titration of Home Insulin|DRUG: Continuous Insulin Infusion|DEVICE: Dexcom G6 Professional Continuous Glucose Monitor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of BI 187004 on the Pharmacokinetics of Cytochrome P450 Substrates (Caffeine, Warfarin, Omeprazole, Metoprolol and Midazolam) and a P Glycoprotein Substrate (Digoxin)
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: midazolam|DRUG: caffeine|DRUG: digoxin|DRUG: warfarin|DRUG: omeprazole|DRUG: BI 187004|DRUG: metoprolol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: NGS-Guided(G) Regimens(R) of Anti-tuberculosis(A) Drugs for the Control(C) and Eradication(E) of MDR-TB
Status: UNKNOWN
Conditions: Multidrug Resistant Tuberculosis
Interventions: DRUG: WHO-approved MDR-TB regimen|DRUG: NGS-guided regimen: Regimen A|DRUG: NGS-guided regimen: Regimen B|DRUG: NGS-guided regimen: Regimen C
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Close Kinetic Chain Exercise With Kinesio Taping in the Management of Patellofemoral Pain Syndrome
Status: TERMINATED
Conditions: Patellofemoral Pain Syndrome
Interventions: DRUG: Acetaminophen 500mg|DEVICE: Kinesio taping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Pharmacokinetic Drug Drug Interaction Between PF-05221304 And PF-06865571 In Healthy Adult Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: PF-06865571 administered Day 7-14|DRUG: PF-06865571 administered Day 1-14|DRUG: PF-05221304 administered Day 1-14|DRUG: PF-05221304 administered Day 7-14
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Vancomycin for C Difficile NAAT+/EIA- Hematology Oncology Patients
Status: COMPLETED
Conditions: Clostridium Difficile Infection|Hematologic Diseases|Bone Marrow Transplant|Oncologic Disorders
Interventions: DRUG: Vancomycin Oral Capsule|DRUG: Placebo Oral Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An Innovative Treatment for Cervical Pre Cancer
Status: COMPLETED
Conditions: Cervical Intraepithelial Neoplasia
Interventions: DEVICE: CryoPen|DEVICE: CO2 standard cryotherapy|DEVICE: Thermocoagulator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lung Irradiation for COVID-19 Pneumonia
Status: WITHDRAWN
Conditions: SARS-CoV 2
Interventions: RADIATION: Phase 1|RADIATION: Phase 1|RADIATION: Phase 2|RADIATION: Phase 2|RADIATION: Phase 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Brain Stimulation and Cognitive Training - Efficacy
Status: COMPLETED
Conditions: Schizophrenia|Schizo Affective Disorder|Bipolar Disorder
Interventions: DEVICE: tDCS (Active)|BEHAVIORAL: BrainHQ|DEVICE: tDCS (Inactive)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Oral Health Promotion Mediated by Teledentistry in Community-dwelling Older Adults of La Araucanía Region, Chile
Status: COMPLETED
Conditions: Oral Health Knowledge|Oral Health Attitudes|Oral Health Self-efficacy
Interventions: DEVICE: Teledentistry oral health promotion|BEHAVIORAL: Face-to-Face oral health promotion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Identifying Electrophysiological Targets for Transcranial Magnetic Stimulation in Cocaine Use Disorder (Pilot Study)
Status: COMPLETED
Conditions: Cocaine Use Disorder
Interventions: DEVICE: iTBS to dmPFC|DEVICE: Sham iTBS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Testing the Addition of Total Ablative Therapy to Usual Systemic Therapy Treatment for Limited Metastatic Colorectal Cancer, The ERASur Study
Status: RECRUITING
Conditions: Metastatic Colorectal Adenocarcinoma|Stage IV Colorectal Cancer AJCC v8
Interventions: PROCEDURE: Stereotactic Ablative Radiotherapy|PROCEDURE: Resection|PROCEDURE: Microwave Ablation|DRUG: Chemotherapy|PROCEDURE: Computed Tomography|PROCEDURE: Magnetic Resonance Imaging|PROCEDURE: Positron Emission Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: As-needed Budesonide/Formoterol Turbuhaler in Stepping Down Period
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Budesonide/Formoterol Fumarate 160 MCG-4.5 MCG Inhalation Powder|DRUG: Budesonide 200Mcg Inhalation Powder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial to Study the Efficacy, Safety, Tolerability and Pharmacokinetics of P2202 in Patients of Type 2 Diabetes
Status: TERMINATED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: P2202|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Ultrasound-Guided Injection With Median Nerve Decompression Surgery in Carpal Tunnel Syndrome
Status: RECRUITING
Conditions: Musculoskeletal Diseases|Median Nerve Disease|Carpal Tunnel Syndrome|Ultrasound-Guided Injection|Surgery
Interventions: PROCEDURE: Minimal Incision Surgery for median nerve decompression|PROCEDURE: Ultrasound-guided perineural injection with 5 cc 5% Dextrose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Remifentanil and Atropine for Intubation in Neonates
Status: COMPLETED
Conditions: Endotracheal Intubation
Interventions: DRUG: Atropine/Remifentanil|DRUG: Fentanyl/Atropine/Succinylcholine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Chewing Gums to Stimulate Intestinal Motility After Cesarean Section
Status: COMPLETED
Conditions: Postoperative Care
Interventions: DIETARY_SUPPLEMENT: Chewing gum|DIETARY_SUPPLEMENT: Oral fluids|OTHER: Intravenous fluids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Micro-interventions Aiming to Optimize Expectations or Self-compassion to Improve Well-being/Reduce Stress and Their Differential Effects
Status: COMPLETED
Conditions: no Specific Clincal Condition Required (Focus is on Persons Who Are Feeling Stressed or Want to Improve Their Wellbeing)
Interventions: BEHAVIORAL: Thinking, writing and imagining
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Phase I Clinical Study of the Safety， Tolerability，Pharmacokinetics, and Initial Efficacy of HRS-6209 Monotherapy in Patients With Advanced Solid Tumors
Status: NOT_YET_RECRUITING
Conditions: Advanced Solid Tumors
Interventions: DRUG: HRS-6209
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tetra-O-Methyl Nordihydroguaiaretic Acid in Treating Patients With Recurrent High-Grade Glioma
Status: COMPLETED
Conditions: Brain and Central Nervous System Tumors
Interventions: DRUG: terameprocol|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Angelica Gigas N. Extract on Improvement of Blood Triglyceride
Status: COMPLETED
Conditions: Hyperlipidemias
Interventions: DIETARY_SUPPLEMENT: Angelica gigas N. extract|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Whey Intake Blood Glucose, Fasting, Thirst, Nausea and Vomiting Levels of Patients Undergoing Elective Hip Fracture Surgery
Status: COMPLETED
Conditions: Elective Hip Fracture Surgery
Interventions: DIETARY_SUPPLEMENT: whey intake group|PROCEDURE: control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Gradual Versus Immediate Goal-dose Enteral Nutrition in Abdominal Surgery Patients
Status: COMPLETED
Conditions: Enteral Nutrition|Postoperative Period|Digestive System Neoplasms
Interventions: OTHER: Enteral nutrition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lay Health Worker Engage, Educate, and Encourage Patients to Share
Status: COMPLETED
Conditions: End of Life|Cancer
Interventions: BEHAVIORAL: Lay Health Worker Intervention|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Ideal Initial Bolus and Infusion Rate for Erector Spinae Plane Block Catheters
Status: WITHDRAWN
Conditions: Pain, Postoperative|Pain, Chest
Interventions: DRUG: Ropivacaine 0.2%-Sodium Chloride 0.9% Injectable Solution bilaterally|DRUG: Ropivacaine 0.2%-Sodium Chloride 0.9% Injectable Solution unilaterally
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of LY2880070 in Participants With Advanced or Metastatic Cancer
Status: RECRUITING
Conditions: Solid Tumors|Colorectal Cancer|Breast Cancer|Ovarian Cancer|Colon Cancer|Rectal Cancer|Neoplasms|Endometrial Cancer|Soft Tissue Sarcoma|Triple Negative Breast Cancer|Pancreas Cancer|Pancreatic Cancer
Interventions: DRUG: LY2880070|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of Autologous Neo-Bladder Construct in Subjects With Neurogenic Bladder Following Spinal Cord Injury
Status: TERMINATED
Conditions: Neurogenic Bladder
Interventions: DEVICE: Autologous neobladder construct
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I Open-Label, Dose-Escalation Study of GSK1059615 in Patients With Solid Tumors or Lymphoma
Status: TERMINATED
Conditions: Solid Tumours
Interventions: DRUG: GSK1059615
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Performance of the Aktiia Optical Blood Pressure Monitoring Device Against Double Auscultation
Status: RECRUITING
Conditions: Hypertension|Blood Pressure|Heart Rate
Interventions: DEVICE: Aktiia.product-us
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Non-Invasive Measurements of Changes in Pulmonary Artery Pressure in Intensive Care Unit Patients Using Electrical Impedance Tomography - A Feasibility Study
Status: NOT_YET_RECRUITING
Conditions: Pulmonary Artery Hypertension
Interventions: DEVICE: Electrical impedance tomography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pilot Study on the Impact of the Mediterranean Diet and Intermittent Fasting
Status: COMPLETED
Conditions: Body Weight Changes
Interventions: BEHAVIORAL: Mediterranean diet guidelines plus intermittent fasting|BEHAVIORAL: UK Eatwell guidelines plus intermittent fasting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of an Artificial Pancreas in Patients Undergoing Pancreatic Resection
Status: UNKNOWN
Conditions: Pancreatic Diseases
Interventions: DEVICE: the closed-loop STG-22 system (Nikkiso Inc, Tokyo, Japan)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Precise Grip Strength Training on PICC Catheter-Related Thrombosis in Cancer Patients
Status: COMPLETED
Conditions: Lung Cancer|Stomach Cancer|Breast Cancer|Liver Cancer|Colon Cancer|Rectal Cancer
Interventions: BEHAVIORAL: Precision grip training|BEHAVIORAL: Use maximum strength grip training|BEHAVIORAL: Health education on routine grip strength training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Alemtuzumab, Busulfan, and Cyclophosphamide Followed By a Donor Stem Cell Transplant in Treating Patients With Hematologic Cancer
Status: TERMINATED
Conditions: Graft Versus Host Disease|Leukemia|Myelodysplastic Syndromes|Myelodysplastic/Myeloproliferative Diseases
Interventions: BIOLOGICAL: alemtuzumab|DRUG: busulfan|DRUG: cyclophosphamide|DRUG: methotrexate|DRUG: tacrolimus|PROCEDURE: allogeneic hematopoietic stem cell transplantation|PROCEDURE: peripheral blood stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Effects of Prehabilitation in Gastric Cancer Patients With Metabolic Syndrome on Perioperative Outcome
Status: COMPLETED
Conditions: Stomach Neoplasms|Metabolic Syndrome X
Interventions: BEHAVIORAL: pre-operative prehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparative Oral Bioavailability Study of MT-1303
Status: COMPLETED
Conditions: Relapsing-remitting Multiple Sclerosis
Interventions: DRUG: MT-1303-FormA|DRUG: MT-1303-FormB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Effects for Lightening the Shiners Among Different Treatments for Rhinitis
Status: RECRUITING
Conditions: Allergic Rhinitis|Vasomotor Rhinitis
Interventions: DRUG: Oral Levocetirizine|DRUG: Combined Intranasal Mometasone Furoate with oral Levocetirizine|DRUG: Combined Intranasal Mometasone Furoate with oral Levocetirizine plus intranasal Oxymetazoline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cholinergic Urticaria - Efficacy of Dupilumab
Status: COMPLETED
Conditions: Cholinergic Urticaria
Interventions: DRUG: Dupilumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I Safety Study of a Cancer Vaccine to Treat HLA-A2 Positive Advanced Stage Ovarian, Breast and Prostate Cancer
Status: COMPLETED
Conditions: Ovarian Neoplasms|Breast Neoplasms|Prostatic Neoplasms
Interventions: BIOLOGICAL: DPX-0907 consists of 7 tumor-specific HLA-A2-restricted peptides, a universal T Helper peptide, a polynucleotide adjuvant, a liposome and Montanide ISA51 VG
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect Of Proprioceptive Neuromuscular Facilitation Techniqueson in Patients With Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: OTHER: PNF Group|OTHER: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: S0007 - Combination Chemotherapy in Treating Patients With Metastatic or Recurrent Head and Neck Cancer
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: DRUG: cisplatin|DRUG: fluorouracil|DRUG: paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transcranial Direct Current Stimulation Combined Neuromuscular Electrical Stimulation on Motor Recovery in Stroke
Status: COMPLETED
Conditions: Chronic Stroke
Interventions: COMBINATION_PRODUCT: tDCS(Intelect Mobile Stimulation and Combination, DJO, France)|COMBINATION_PRODUCT: NMES(Enraf Nonius, Endomed-182, Netherlands)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of Donor T Cells Sensitized With Pentadecapeptides of the CMV-PP65 Protein for the Treatment of Cytomegalovirus (CMV) Infections Following Allogeneic Hematopoietic Stem Cell Transplants
Status: COMPLETED
Conditions: Cytomegalovirus Infections
Interventions: BIOLOGICAL: CMV-Peptide-Specific T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study With Modafinil in Patients Treated With Docetaxel-Based Chemotherapy for Metastatic Breast or Prostate Cancer (MOTIF)
Status: COMPLETED
Conditions: Prostatic Neoplasms|Breast Cancer
Interventions: DRUG: DOCETAXEL(XRP6976) + MODAFINIL|DRUG: Modafinil|DRUG: Placebo of Modafinil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase II Trial Comparing Gemcitabine and Pazopanib Versus Gemcitabine and Docetaxel for Patients With Advanced Soft Tissue Sarcoma
Status: COMPLETED
Conditions: Sarcoma
Interventions: DRUG: Gemcitabine and Pazopanib|DRUG: Gemcitabine and Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Pharmacokinetics (PK) of Darunavir (DRV) and Cobicistat (COBI) After a Single Oral Administration of Darunavir/Cobicistat Fixed-Dose Combination in Healthy Japanese Adult Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Darunavir/Cobicistat
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Delivery of Enhance Fitness Trial
Status: UNKNOWN
Conditions: Arthritis|Rheumatoid Arthritis|Fibromyalgia|Gout|Osteoarthritis|Lupus or SLE
Interventions: BEHAVIORAL: Tele-Enhance Fitness|BEHAVIORAL: In-person Enhance Fitness
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of Chidamide Combined With Fulvestrant in the Treatment of Hormone Receptor-positive Advanced Breast Cancer
Status: UNKNOWN
Conditions: Advanced Breast Cancer
Interventions: DRUG: Chidamide|DRUG: Fulvestrant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Confirm the Safety and Performance of Avance Solo NPWT System
Status: COMPLETED
Conditions: Acute Wound|Traumatic Wound|Skin Graft|Skin Flap|Subacute Wound|Dehiscence
Interventions: DEVICE: Avance Solo NPWT System
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Weight, Energy, Lipids, and the Liver (WELL) Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Nonalcoholic Fatty Liver
Interventions: OTHER: Soybean Oil Foods|OTHER: Palm Oil Foods
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: On-table Renal Perfusion Evaluation Renal Artery Stenosis or Obstruction
Status: UNKNOWN
Conditions: Renal Artery Stenosis|Aortic Dissection|Renal Perfusion|Renal Artery Obstruction
Interventions: PROCEDURE: Endovascular therapy and Imaging Acquisition
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Neratinib and Paclitaxel With or Without Pertuzumab and Trastuzumab Before Combination Chemotherapy in Treating Patients With Metastatic or Locally Advanced Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Inflammatory Carcinoma|Locally Advanced Breast Carcinoma|Metastatic Breast Carcinoma|Stage III Breast Cancer AJCC v7|Stage IIIA Breast Cancer AJCC v7|Stage IIIB Breast Cancer AJCC v7|Stage IIIC Breast Cancer AJCC v7|Stage IV Breast Cancer AJCC v6 and v7
Interventions: DRUG: Cyclophosphamide|DRUG: Doxorubicin|OTHER: Laboratory Biomarker Analysis|DRUG: Neratinib|DRUG: Paclitaxel|BIOLOGICAL: Pertuzumab|BIOLOGICAL: Trastuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimal Anesthesia for Morbidly Obese Patients
Status: COMPLETED
Conditions: Obesity|Anesthesia
Interventions: PROCEDURE: Exploring potential risk factors of difficult intubation using ultrasound|PROCEDURE: Radial artery catheterization using ultrasound guidance or blind palpation|DEVICE: Comparing the effectiveness of preoxygenation between high-flow nasal cannula and facemask|DRUG: Type of volatile anesthetics and M-Entropy guidance of anesthesia depth
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treating Leg Symptoms in Women With X-linked Adrenoleukodystrophy
Status: RECRUITING
Conditions: Adrenoleukodystrophy|Restless Legs Syndrome
Interventions: DRUG: Pramipexole|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT