pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Topical Autologous Serum Application for the Treatment of Corneal Epithelium Defect After Ocular Surgeries
Status: COMPLETED
Conditions: Corneal Epithelial Defect|Diabetic Retinopathy|Penetrating Keratoplasty
Interventions: OTHER: autologous serum|OTHER: Non-autologous serum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Risankizumab Therapy Versus Placebo for Subjects With Psoriasis in the Russian Federation
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: risankizumab|DRUG: placebo for rizankizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Withdrawal Study of Memantine in Pediatric Patients With Autism, Asperger's Disorder, or Pervasive Developmental Disorder Not Otherwise Specified Previously Treated With Memantine
Status: COMPLETED
Conditions: Autistic Disorder|Autism|Asperger's Disorder|Asperger Syndrome|Autism Spectrum Disorders|Pervasive Developmental Disorder - Not Otherwise Specified (PDD-NOS)
Interventions: DRUG: Memantine Hydrochloride (HCl)|DRUG: Memantine Hydrochloride (HCl)|DRUG: Placebo capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Chronic Venous Thrombosis: Relief With Adjunctive Catheter-Directed Therapy (The C-TRACT Trial)
Status: RECRUITING
Conditions: Deep Vein Thrombosis|Venous Stasis|Venous Insufficiency|Venous Leg Ulcer|Venous Reflux|Post Thrombotic Syndrome
Interventions: DEVICE: Stents
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Stimulation of the Efferent Loop Before Loop Ileostomy Closure
Status: UNKNOWN
Conditions: Ileostomy - Stoma|Ileostomy; Complications|Stoma Ileostomy|Ileus Paralytic
Interventions: PROCEDURE: efferent limb stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Treatment of Chronic Constipation in Children With Lactobacillus Reuteri
Status: UNKNOWN
Conditions: Constipation
Interventions: DIETARY_SUPPLEMENT: Biogaia|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Effect of Attentional Touch in Stabilometric Assessments
Status: COMPLETED
Conditions: Postural Balance
Interventions: OTHER: TOUCH ATTENTIVE TREATMENT|OTHER: AUDITORY ATTENTIVE TREATMENT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect of Dexmedetomidine on Kidney Function in EVAR
Status: UNKNOWN
Conditions: Acute Kidney Injury|Dexmedetomidine|Endovascular Aortic Repair
Interventions: DRUG: Dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Drug/Drug Interactions With F901318
Status: WITHDRAWN
Conditions: Invasive Aspergillosis
Interventions: DRUG: cyclosporine A|DRUG: Posaconazole|DRUG: Pantoprazole|DRUG: F901318|DRUG: Tacrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Breath Combined With CT for Diagnoses of Pulmonary Nodules
Status: UNKNOWN
Conditions: Non-small Cell Lung Cancer|Pulmonary Nodule, Multiple
Interventions: DIAGNOSTIC_TEST: Pathological examinations as the golden diagnosis criteria|DIAGNOSTIC_TEST: Breath test combined with computed tomography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Mediating Effects of Decentering on Self-Management of Stress and End of Life Planning
Status: COMPLETED
Conditions: Stage IV Gastrointestinal Cancer|Advanced Gynecological Cancer
Interventions: BEHAVIORAL: Stop, Breathe & Think™|BEHAVIORAL: End of Life Planning Videos|BEHAVIORAL: Caregiver wellness videos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pre-operative Biliary SEMS RCT During Neoadjuvant Therapy
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DEVICE: WallFlex™ Biliary RX Fully Covered/Uncovered Stent System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Comparison of an Experimental Power Brush Compared to a Manual Toothbrush
Status: COMPLETED
Conditions: Gingivitis|Dental Plaque
Interventions: DEVICE: Power toothbrush|DEVICE: Manual toothbrush
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Symptom Based Treatment Affects Brain Plasticity - Cognitive Training in Patients With Affective Symptoms
Status: COMPLETED
Conditions: Depression|Schizophrenia
Interventions: PROCEDURE: fMRI|BEHAVIORAL: Neurofeedback|OTHER: PANAS|OTHER: BDI-II|OTHER: ERQ
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: HighFLO Study - HighLife Trans-septal Mitral Valve Replacement (TSMVR) Feasibility Study of the Open Cell CLARITY Valve
Status: RECRUITING
Conditions: Mitral Regurgitation
Interventions: DEVICE: CLARITY
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Perineural Dexamethasone in the Adductor Canal Block
Status: RECRUITING
Conditions: Post Operative Pain
Interventions: PROCEDURE: group Dexamethasone|PROCEDURE: group Controle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Cerebral Activation During Different Rehabilitation Tasks of Lower Limb in Virtual Mirror Therapy in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DEVICE: Observation (OBS)|DEVICE: Observation and imagination (OBS-IM)|DEVICE: Observation and realization (OBS-REAL)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Treatment of Refractory Diabetic Macular Edema With Infliximab
Status: TERMINATED
Conditions: Diabetic Macular Edema|Visual Acuity|Diabetic Retinopathy
Interventions: DRUG: infliximab|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: VentrAssistTM LVAD as a Bridge to Cardiac Transplantation - Feasibility Trial
Status: COMPLETED
Conditions: End-Stage Heart Failure|Cardiomyopathies
Interventions: DEVICE: VentrAssist Left Ventricular Assist Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety/Efficacy Study of Drospirenone/Estradiol to Treat Postmenopausal Chinese Women With Vasomotor Symptoms.
Status: COMPLETED
Conditions: Vasomotor Symptoms
Interventions: DRUG: Estradiol/DRSP (Angeliq, BAY86-4891)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: PH2 Trial in Patients With Relapsed/Refractory Chronic Lymphocytic Leukemia (CLL) With a Combination of Bendamustine & Ofatumumab
Status: WITHDRAWN
Conditions: Chronic Lymphocytic Leukemia (CLL)
Interventions: DRUG: ofatumumab + bendamustine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevention of Nosocomial E. Coli Infections After Placement of an Indwelling Catheter During Pelvic Surgery: an Evaluation of Cranberry Gel Capsules
Status: COMPLETED
Conditions: Cross Infection|Bacteriuria
Interventions: DIETARY_SUPPLEMENT: cranberry type A pro anthocyandines|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A New Ligation Using the Double-loop Clips Technique Versus Traditional Techniques in the Treatment of Large Wounds After Endoscopic Resection
Status: UNKNOWN
Conditions: Polyps|Closure; Delay
Interventions: DEVICE: double-loop clips|DEVICE: Titanium Clip
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Study Comparing AVP-786 With AVP-923
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: AVP-786|DRUG: AVP-923
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Study to Evaluate the Sexual Functioning of Healthy Adults After Receiving Vilazodone, Paroxetine or Placebo
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Vilazodone 20 mg|DRUG: Vilazodone 40 mg|DRUG: Paroxetine 20 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Optimizing the Effectiveness of Selective Serotonin Reuptake Inhibitors (SSRIs) in Treatment-Resistant Depression
Status: COMPLETED
Conditions: Depression
Interventions: DRUG: S-adenosyl methione (SAMe)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transcutaneous Vagus Nerve Stimulation in Heart Failure
Status: RECRUITING
Conditions: Heart Failure With Preserved Ejection Fraction|Heart Failure With Midrange Ejection Fraction
Interventions: DEVICE: Active tVNS|DEVICE: Sham tVNS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oxytocin in Adolescents With Autism Spectrum Disorders
Status: TERMINATED
Conditions: Autism Spectrum Disorder
Interventions: DRUG: OCYTOCINA - SPRAY NASAL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial on Sequential Immunization of Recombinant COVID-19 Vaccine (CHO Cells) and Inactivated COVID-19 Vaccine (Vero Cells) in Population Aged 18 Years and Above
Status: ACTIVE_NOT_RECRUITING
Conditions: COVID-19 Pneumonia|Coronavirus Infections
Interventions: BIOLOGICAL: Recombinant COVID-19 Vaccine (CHO cell)|BIOLOGICAL: COVID-19 vaccine (Vero cells)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Phase 2b/3 Trial of NuSepin® in COVID-19 Pneumonia Patients
Status: RECRUITING
Conditions: COVID-19 Pneumonia
Interventions: DRUG: NuSepin® 0.2 mg/kg|DRUG: NuSepin® 0.4 mg/kg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Transcutaneous Electrical Acupoint Stimulation for Prevention of Postoperative Nausea and Vomiting
Status: COMPLETED
Conditions: Postoperative Nausea and Vomiting
Interventions: DEVICE: TEAS|DEVICE: TEAS without electrical stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Physical Therapy in the Treatment of Carpal Tunnel Syndrome
Status: UNKNOWN
Conditions: Carpal Tunnel Syndrome
Interventions: OTHER: Median nerve neural mobilization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: CANF-Comb-II PET-MR in Atherosclerosis Multisite
Status: RECRUITING
Conditions: Carotid Atherosclerosis|Asymptomatic Carotid Artery Stenosis|Carotid Artery Atheroma
Interventions: DRUG: 64Cu-25%-CANF-Comb|DRUG: 64Cu-25%-CANF-Comb
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Probiotic Supplementation on Lactose Maldigestion Induced by Fat-free Milk
Status: COMPLETED
Conditions: Gastrointestinal Symptoms|Breath Test
Interventions: DIETARY_SUPPLEMENT: Probiotic|DIETARY_SUPPLEMENT: Lactrase|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Galactooligosaccharide (GOS) Supplementation and Calcium Absorption in Girls
Status: COMPLETED
Conditions: Osteoporosis
Interventions: DIETARY_SUPPLEMENT: Galactooligosaccharide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Iron Deficiency Anemia, Iron Supplementation and Genomic Stability in Infants
Status: UNKNOWN
Conditions: Anemia|Iron-deficiency
Interventions: DRUG: Weekly Ferrous Sulfate|DRUG: Daily Ferrous Sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Cognitive-Behavioral Dysfunctions and the Potential of Neuroplasticity in Brain Tumors Patients During Radiotherapy
Status: RECRUITING
Conditions: Brain Tumors|Radiotherapy
Interventions: BEHAVIORAL: Exercise treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Fludarabine Based Conditioning for Allogeneic Transplantation for Advanced Hematologic Malignancies
Status: COMPLETED
Conditions: Acute Myeloid Leukemia|Acute Leukemia|Chronic Myelogenous Leukemia|Malignant Lymphoma|Hodgkin's Disease|Multiple Myeloma|Lymphocytic Leukemia|Myeloproliferative Disorder|Polycythemia Vera|Myelofibrosis|Aplastic Anemia
Interventions: DRUG: fludarabine/busulfan|DRUG: fludarabine/ melphalan|DRUG: ATG
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Efficacy and Safety of Letrozole Combined With Trastuzumab in Patients With Metastatic Breast Cancer
Status: TERMINATED
Conditions: Metastatic Breast Cancer
Interventions: DRUG: Letrozole|DRUG: Trastuzumab plus Letrozole|DRUG: Letrozole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Efficacy of Subcutaneous Phosphatidylcholine and Deoxycholate Injections for Localized Fat Removal
Status: TERMINATED
Conditions: Obesity
Interventions: DRUG: Phosphatidylcholine Deoxycholate|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Imatinib Mesylate and Cytarabine in Treating Patients With Newly Diagnosed Chronic Myeloid Leukemia
Status: UNKNOWN
Conditions: Leukemia
Interventions: DRUG: cytarabine|DRUG: imatinib mesylate
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Mechanical Ventilation Controlled by the Electrical Activity of the Patient's Diaphragm - Effects of Changes in Ventilator Parameters on Breathing Pattern
Status: COMPLETED
Conditions: Mechanical Ventilation
Interventions: DEVICE: neurally adjusted ventilatory assist (NAVA)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effects of Medication Induced Blood Pressure Reduction on Cerebral Hemodynamics in Hypertensive Frail Elderly
Status: COMPLETED
Conditions: Hypertension|Frailty|Old Age; Dementia|Orthostatic Intolerance|Orthostatic Hypotension|Cerebral Hypoperfusion
Interventions: DRUG: Antihypertensive Agents
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Chiropractic Care on Opioid Use for Chronic Spinal Pain: A Feasibility Study
Status: NOT_YET_RECRUITING
Conditions: Back Pain
Interventions: OTHER: Usual Medical Care|OTHER: Usual Medical Care + Chiropractic Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Short Term Effect of Glucocorticoids on Brown Adipose Tissue Thermogenesis in Humans
Status: COMPLETED
Conditions: Brown Adipose Tissue
Interventions: DRUG: Prednisone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy of Marine By-product Hydrolysate on the Reduction of Atopic Dermatitis Symptoms
Status: COMPLETED
Conditions: Atopic Dermatitis|Eczema
Interventions: DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: ACT01|DIETARY_SUPPLEMENT: ACT02
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Prone Positioning and Abdominal Binding on Lung and Muscle Protection in ARDS Patients During Spontaneous Breathing
Status: RECRUITING
Conditions: Acute Respiratory Distress Syndrome|Mechanical Ventilation Complication|ICU Acquired Weakness
Interventions: PROCEDURE: Prone Positioning|PROCEDURE: Thoracoabdominal Binding|PROCEDURE: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Dose Escalation For INtraprostatic LEsions
Status: RECRUITING
Conditions: Prostatic Neoplasms
Interventions: RADIATION: Prostate SBRT with Focal Boost|DRUG: Triptorelin Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Carboplatin and Paclitaxel With or Without Bevacizumab in Treating Patients With Stage III or Stage IV Ovarian Epithelial, Primary Peritoneal, or Fallopian Tube Cancer
Status: COMPLETED
Conditions: Fallopian Tube Clear Cell Adenocarcinoma|Fallopian Tube Endometrioid Adenocarcinoma|Fallopian Tube Mucinous Adenocarcinoma|Fallopian Tube Serous Adenocarcinoma|Fallopian Tube Transitional Cell Carcinoma|Malignant Ovarian Mixed Epithelial Tumor|Ovarian Brenner Tumor|Ovarian Clear Cell Adenocarcinoma|Ovarian Endometrioid Adenocarcinoma|Ovarian Mucinous Adenocarcinoma|Ovarian Serous Adenocarcinoma|Ovarian Transitional Cell Carcinoma|Primary Peritoneal Serous Adenocarcinoma|Stage IIIA Fallopian Tube Cancer|Stage IIIA Ovarian Cancer|Stage IIIA Primary Peritoneal Cancer|Stage IIIB Fallopian Tube Cancer|Stage IIIB Ovarian Cancer|Stage IIIB Primary Peritoneal Cancer|Stage IIIC Fallopian Tube Cancer|Stage IIIC Ovarian Cancer|Stage IIIC Primary Peritoneal Cancer|Stage IV Fallopian Tube Cancer|Stage IV Ovarian Cancer|Stage IV Primary Peritoneal Cancer|Undifferentiated Fallopian Tube Carcinoma|Undifferentiated Ovarian Carcinoma
Interventions: BIOLOGICAL: Bevacizumab|DRUG: Carboplatin|OTHER: Laboratory Biomarker Analysis|DRUG: Paclitaxel|OTHER: Placebo|OTHER: Quality-of-Life Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Paclitaxel Plus Pembrolizumab vs. Paclitaxel Weekly in ER+ Luminal B Metastatic Breast Cancer
Status: WITHDRAWN
Conditions: Breast Cancer
Interventions: DRUG: Pembrolizumab|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Central Mechanisms of Intervention for Low Back Pain
Status: COMPLETED
Conditions: Low Back Pain
Interventions: OTHER: Spinal Manipulation|OTHER: Spinal Mobilization|OTHER: Static Touch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Functional CT Assessment of Pulmonary Arterial Dysfunction in Smoking Associated Emphysema
Status: RECRUITING
Conditions: Emphysema
Interventions: DRUG: Hypoxia administration study group|DRUG: Hyperoxia administration study group|DRUG: Sildenafil
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Fosrenol for Enhancing Dietary Protein Intake in Hypoalbuminemic Dialysis Patients (FrEDI) Study
Status: COMPLETED
Conditions: End-Stage Renal Disease
Interventions: OTHER: Meals during hemodialysis accompanied by lanthanum carbonate to control phosphorus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: BATTLE-2 Program: A Biomarker-Integrated Targeted Therapy Study in Previously Treated Patients With Advanced Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DRUG: Erlotinib|DRUG: AZD6244|DRUG: MK-2206|DRUG: Sorafenib|DRUG: Erlotinib|DRUG: MK-2206
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: P-PSMA-101 CAR-T Cells in the Treatment of Subjects With Metastatic Castration-Resistant Prostate Cancer (mCRPC) and Advanced Salivary Gland Cancers (SGC)
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostatic Neoplasms, Castration-Resistant|Neoplasms by Histologic Type|Neoplasms, Prostate|Prostate Cancer|Metastatic Castration-resistant Prostate Cancer|Neoplasms|Prostatic Neoplasms|Genital Neoplasms, Male|Urogenital Neoplasms|Neoplasms by Site|Prostatic Disease|Salivary Gland Cancer|Salivary Gland Tumor|Adenoid Cystic Carcinoma|Salivary Duct Carcinoma|Mucoepidermoid Carcinoma|Acinic Cell Tumor
Interventions: BIOLOGICAL: P-PSMA-101 CAR-T cells|DRUG: Rimiducid
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: COVID-19 Blood Pressure Endothelium Interaction Study (OBELIX)
Status: COMPLETED
Conditions: COVID|Hypertension
Interventions: DIAGNOSTIC_TEST: ABPM|DIAGNOSTIC_TEST: ECG|DIAGNOSTIC_TEST: FMD|DIAGNOSTIC_TEST: PWV|DIAGNOSTIC_TEST: Rarefaction
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety of Imipenem+Cilastatin/Relebactam (MK-7655A) Versus Colistimethate Sodium+Imipenem+Cilastatin in Imipenem-Resistant Bacterial Infection (MK-7655A-013)
Status: COMPLETED
Conditions: Bacterial Infections
Interventions: DRUG: Imipenem+Cilastatin/Relebactam|DRUG: Colistimethate sodium (CMS)|DRUG: Imipenem+Cilastatin|DRUG: Placebo to CMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Association of Leucocyte Telomere Length With DPAS Score in Skin Aging
Status: RECRUITING
Conditions: Aging|Skin Laxity
Interventions: GENETIC: Leucocyte Telomere Length from blood draw
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Retrospective, Open-label, Uncontrolled Cohort Study to Assess the Effectiveness and Safety of Lactulose Retention Enema in the Treatment of Cirrhotic Patients With Grade 3 or 4 (West Haven Criteria) Hepatic Encephalopathy (HE) [The RETRO Study]
Status: COMPLETED
Conditions: Hepatic Encephalopathy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Investigation of Different Relaxation Techniques in Eliciting a Relaxation Response
Status: COMPLETED
Conditions: Stress, Psychological
Interventions: OTHER: Guided Imagery Relaxation Tape|OTHER: Music Listening|OTHER: Relaxation Lighting|OTHER: Meditation and Relaxation Light|OTHER: Music and Relaxation Light|OTHER: Control/Silence
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Oculomotor Exercises in the Warm-up on Forehand and Backhand Stroke Performance in Tennis Players
Status: RECRUITING
Conditions: Supportive Care
Interventions: BEHAVIORAL: Oculo-motor exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Spinal Root and Spinal Cord Stimulation for Restoration of Function in Lower-Limb Amputees
Status: COMPLETED
Conditions: Traumatic Amputation of Lower Extremity|Phantom Limb Pain
Interventions: DEVICE: Spinal cord stimulator
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Temperature Change of the Pulpal Floor and Restoration With Preheated Resin Composite (A Randomized Clinical Trial)
Status: COMPLETED
Conditions: Preheating of Resin Composite
Interventions: OTHER: preheating of resin composite
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Use of Oral Probiotics as an Adjunctive Therapy to Fluconazole in the Treatment of Yeast Vaginitis
Status: UNKNOWN
Conditions: Vaginal Candidiasis
Interventions: DRUG: Probiotics (Natural product)|DRUG: Probiotics (L. rhamnosus GR-1 and L. reuteri RC-14)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: 3BNC117 Monoclonal Antibody in HIV-infected Subjects During Treatment Interruption
Status: COMPLETED
Conditions: HIV-1 Infection
Interventions: DRUG: 3BNC117|OTHER: ART Interruption
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single-Dose HPV Vaccination for the Prevention of Cervical Cancer in Young Adult Women in Costa Rica, The PRISMA ESCUDDO Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Cervical Carcinoma|Human Papillomavirus Infection
Interventions: BIOLOGICAL: Diphtheria Toxoid/Tetanus Toxoid/Acellular Pertussis Vaccine Adsorbed|OTHER: Questionnaire Administration|BIOLOGICAL: Recombinant Human Papillomavirus Bivalent Vaccine|BIOLOGICAL: Recombinant Human Papillomavirus Nonavalent Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Bioavailability of Two Sustained-release Theophylline Products in Healthy Males
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: anhydrous theophylline, 350 mg|DRUG: anhydrous theophylline, 300 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multicentric Randomized Clinical Trial to Evaluate the Long-term Effectiveness of a Motivational Intervention Against Smoking, Based on the Information Obtained From Spirometry in Primary Care.
Status: COMPLETED
Conditions: Smoking Cessation
Interventions: BEHAVIORAL: Spirometry
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety and Immunogenicity Study of Recombinant Thrombin (rThrombin) in Pediatric Participants
Status: COMPLETED
Conditions: Blood Loss, Surgical
Interventions: BIOLOGICAL: rThrombin, 1000 IU/mL
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Peri-capsular Nerve Group Block Versus Fascia Iliaca Block for Hip Arthroplasty
Status: UNKNOWN
Conditions: Post Operative Pain Management
Interventions: PROCEDURE: Pericapsular nerve group block|PROCEDURE: Fascia Iliaca BLock
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effects of Azithromycin on MAC Disease Prevention in HIV-Positive Patients
Status: COMPLETED
Conditions: Mycobacterium Avium-intracellulare Infection|HIV Infections
Interventions: DRUG: Azithromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: Culturally Tailored Decision Aid for Hispanic Patients Diagnosed With Prostate Cancer
Status: WITHDRAWN
Conditions: Prostate Cancer
Interventions: BEHAVIORAL: Decision Aid Tool|BEHAVIORAL: baseline survey|BEHAVIORAL: follow-up surveys
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Breathing Techniques and Meditation for Health Care Workers During COVID-19 Pandemic
Status: ACTIVE_NOT_RECRUITING
Conditions: COVID-19 Infection
Interventions: OTHER: Media Intervention|PROCEDURE: Meditation Therapy|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration|PROCEDURE: Yoga
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Rituximab, Prednisone, Cyclophosphamide, Doxorubicin, Vincristine, and Yttrium Y 90 Ibritumomab Tiuxetan in Treating Patients With Previously Untreated Mantle Cell Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: BIOLOGICAL: rituximab|DRUG: cyclophosphamide|DRUG: doxorubicin hydrochloride|DRUG: prednisone|DRUG: vincristine sulfate|RADIATION: yttrium Y 90 ibritumomab tiuxetan
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Immunogenicity and Safety of the SARS-CoV-2 mRNA Vaccine CVnCoV in Elderly Adults Compared to Younger Adults for COVID-19
Status: WITHDRAWN
Conditions: Coronavirus|Covid19|SARS-CoV-2|Severe Acute Respiratory Syndrome
Interventions: BIOLOGICAL: CVnCoV Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Anesthesia Technique on Outcome After Hip Fracture Surgery in Elderly Adult Patients
Status: COMPLETED
Conditions: Hip Fracture
Interventions: DRUG: Desflurane|DRUG: Propofol|DRUG: Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Intra-ovarian Injection of MSC-EVs in Idiopathic Premature Ovarian Failure
Status: RECRUITING
Conditions: Premature Ovarian Failure
Interventions: BIOLOGICAL: Intra-ovarian injection of bone marrow mesenchymal stromal cells-derived extracellular vesicles
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 2, Open-Label Study to Evaluate the Safety and Effects of HLX-1502 in Patients With Neurofibromatosis Type 1
Status: NOT_YET_RECRUITING
Conditions: Neurofibromatosis Type 1
Interventions: DRUG: HLX-1502
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Explore the Influence of Two Opioid Pain Medications on Bacterial Composition in the Gut and Other Gastrointestinal Aspects
Status: COMPLETED
Conditions: Severe Chronic Pain
Interventions: DRUG: OXN PR followed by OxyPR tablets|DRUG: OxyPR followed by OXN PR tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing Injections With Poly-L-Lactic Acid in the Temporal Fossa vs. Extended Temporal Fossa + Hairline
Status: COMPLETED
Conditions: Aging
Interventions: DEVICE: Traditional technique|DEVICE: Experimental technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Venetoclax Combined With Azacitidine and CAG in Refractory/Relapse Acute Myeloid Leukemia
Status: RECRUITING
Conditions: Refractory/Relapse Acute Myeloid Leukemia
Interventions: DRUG: Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation, the Histomorphometric Study of Nanocrystalline Hydroxyapatite (Nano Bone) Wif Alendronate in the Preservation of the Tooth Socket
Status: COMPLETED
Conditions: Bone Resorption
Interventions: DRUG: Alendronate 20 mg|PROCEDURE: Nanocrystal hydroxyapatite
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Determine the Safety and Efficacy of the RSV F Vaccine to Protect Infants Via Maternal Immunization
Status: COMPLETED
Conditions: Respiratory Syncytial Virus Infections
Interventions: BIOLOGICAL: RSV F vaccine with adjuvant|BIOLOGICAL: Formulation buffer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Narrow Band Imaging in the Characterization of Serrated Lesions
Status: COMPLETED
Conditions: Serrated Polyps|Sessile Serrated Adenoma|Colorectal Neoplasms
Interventions: DEVICE: NBI|DEVICE: WLE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Non-invasive Evaluation of Graft Condition in Adult Patients With Kidney Transplant Using Ultrasound Localization Microscopy and Multispectral Optoacoustic Tomography
Status: RECRUITING
Conditions: Kidney Transplant|Kidney Biopsy
Interventions: DEVICE: ULM and MSOT
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Immediate Curative vs Conservative Treatment in Older Men With M0, High-risk Prostate Cancer
Status: RECRUITING
Conditions: Prostate Cancer
Interventions: RADIATION: Radiotherapy or surgery|OTHER: initial observation|DRUG: Hormone therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I Study of XH-S003 in Healthy Volunteers
Status: NOT_YET_RECRUITING
Conditions: Healthy Adults
Interventions: DRUG: XH-S003|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of CBT and APT on Managing Child Anxiety in Dental Office
Status: ACTIVE_NOT_RECRUITING
Conditions: Dental Anxiety
Interventions: BEHAVIORAL: Cognitive behavioral therapy|BEHAVIORAL: Auricular plaster therapy|BEHAVIORAL: Tell Show Do
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Comparison of Adhesive Latch Device to Subcuticular Skin Closure at the Time of Cesarean Section
Status: UNKNOWN
Conditions: Wound
Interventions: DEVICE: Dermaclip|DEVICE: Subcuticular suture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Nurse Led Intervention to Promote Physical Activity
Status: COMPLETED
Conditions: Sedentary Behavior|Cardiovascular Risk Factor
Interventions: OTHER: Nurse led tutorial on lifestyle management and pedometer hand-out|OTHER: Steps goal setting and supporting phone calls
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Combination Osteogenic Therapy in Established Osteoporosis
Status: COMPLETED
Conditions: Osteoporosis, Post-Menopausal
Interventions: DRUG: PTH 1-34|DRUG: MFPSR-fluoride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Efficacy of CCX140-B in Subjects With Diabetic Nephropathy
Status: COMPLETED
Conditions: Diabetic Nephropathy|Type 2 Diabetes Mellitus
Interventions: DRUG: Placebo|DRUG: CCX140-B|DRUG: CCX140-B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Morning Light Treatment for Traumatic Stress: The Role of Amygdala Reactivity
Status: COMPLETED
Conditions: Stress
Interventions: DEVICE: Light therapy A via the Re-Timer®|DEVICE: Light therapy B via the Re-Timer®|DEVICE: Light therapy C via the Re-Timer®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: BEACON Care ® System Assisting Ventilation in Pressure Support Ventilation (PSV) Patient
Status: COMPLETED
Conditions: Artificial Respiration
Interventions: DEVICE: Pressure Support Over Support|DEVICE: Pressure Support Under Support|DEVICE: PEEP Over Level|DEVICE: PEEP Under Level
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Determine the Efficacy and Safety of Cabergoline for the Treatment of Patients With RLS
Status: COMPLETED
Conditions: Restless Legs Syndrome
Interventions: DRUG: cabergoline|DRUG: levodopa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Safety and Efficacy of Early Calcineurin Inhibitor Withdrawal in Primary Renal Allografts
Status: COMPLETED
Conditions: Primary Renal Allograft
Interventions: DRUG: mycophenolate mofetil|DRUG: sirolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pembrolizumab in Treating Patients With Metastatic or Unresectable Gastroesophageal Adenocarcinoma
Status: COMPLETED
Conditions: Advanced Gastroesophageal Junction Adenocarcinoma|Clinical Stage III Esophageal Adenocarcinoma AJCC v8|Clinical Stage III Gastric Cancer AJCC v8|Clinical Stage IV Esophageal Adenocarcinoma AJCC v8|Clinical Stage IV Gastric Cancer AJCC v8|Clinical Stage IVA Esophageal Adenocarcinoma AJCC v8|Clinical Stage IVA Gastric Cancer AJCC v8|Clinical Stage IVB Esophageal Adenocarcinoma AJCC v8|Clinical Stage IVB Gastric Cancer AJCC v8|Gastroesophageal Junction Adenocarcinoma|Metastatic Gastroesophageal Junction Adenocarcinoma|Pathologic Stage III Esophageal Adenocarcinoma AJCC v8|Pathologic Stage III Gastric Cancer AJCC v8|Pathologic Stage IIIA Esophageal Adenocarcinoma AJCC v8|Pathologic Stage IIIA Gastric Cancer AJCC v8|Pathologic Stage IIIB Esophageal Adenocarcinoma AJCC v8|Pathologic Stage IIIB Gastric Cancer AJCC v8|Pathologic Stage IIIC Gastric Cancer AJCC v8|Pathologic Stage IV Esophageal Adenocarcinoma AJCC v8|Pathologic Stage IV Gastric Cancer AJCC v8|Pathologic Stage IVA Esophageal Adenocarcinoma AJCC v8|Pathologic Stage IVB Esophageal Adenocarcinoma AJCC v8|Postneoadjuvant Therapy Stage III Gastric Cancer AJCC v8|Postneoadjuvant Therapy Stage IV Gastric Cancer AJCC v8|Unresectable Gastroesophageal Junction Adenocarcinoma
Interventions: BIOLOGICAL: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Tenofovir Disoproxil on Mother-to-child Transmission of HBV in Tokombéré, Cameroon in Pregnant Women
Status: NOT_YET_RECRUITING
Conditions: Hepatitis B Virus - Chronic Active
Interventions: DRUG: Fumarate, Tenofovir Disoproxil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Fenofibrate on Endothelial Function and High-density Lipoproteins (HDL)in Patients With Coronary Heart Disease
Status: COMPLETED
Conditions: Coronary Heart Disease|Hyperlipidemia
Interventions: DRUG: fenofibrate|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Effect of Inhibitory Kinesio-tape of the Upper Trapezius on Lower Trapezius Muscle Excitation
Status: COMPLETED
Conditions: Scapular Dyskinesis
Interventions: DEVICE: kinesio-tape
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Intravesical Adoptive Cell Therapy w/ TIL for BCG Exposed High Grade NMIBC
Status: RECRUITING
Conditions: Urothelial Carcinoma|Non-Invasive Bladder Urothelial Carcinoma
Interventions: BIOLOGICAL: Adoptive Cell Therapy with Tumor-infiltrating Lymphocytes (TIL)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aldafermin (NGM282) for Chronic Diarrhea Due to Bile Acid Malabsorption (BAM)
Status: COMPLETED
Conditions: Chronic Diarrhea|Irritable Bowel Syndrome With Diarrhea|Bile Acid Malabsorption|Bile Acid Diarrhea|Bile Acid Malabsorption Syndrome Type II|Functional Diarrhea
Interventions: DRUG: Aldafermin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Ketogenic Diet on Malignant Tumors- Recurrence and Progress
Status: UNKNOWN
Conditions: Malignant Tumors
Interventions: OTHER: Nutritional support with Standard diet|OTHER: Nutritional intervention with the Ketogenic diet
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: A Study on Building a Voice Cohort for the Development of a Non-face-to-face Machine Learning Diagnostic and Monitoring Platform Using Voice Analysis and Various Sensors in Patients With Dysphagia.
Status: RECRUITING
Conditions: Deglutition Disorders
Interventions: DIAGNOSTIC_TEST: Patients scheduled for VFSS testing group
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: to Evaluate the Safety and Efficacy of Pitavastatin in Patients With IFG and Hyperlipidemia
Status: COMPLETED
Conditions: HbA1c Level Associated With Lipid Compositions
Interventions: DRUG: Pitavastatin calcium 4mg|DRUG: Pitavastatin calcium 2mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: AG-858 in Patients Who Are Cytogenetically Positive After Treatment With Gleevec™
Status: TERMINATED
Conditions: Leukemia, Myeloid, Chronic
Interventions: DRUG: Autologous HSP-70 Protein-Peptide Complex (AG-858) Plus Gleevec™.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Targeted Phase I/II Trial of ZD6474 (Vandetanib; ZACTIMA) Plus the Proteasome Inhibitor, Bortezomib (Velcade ), in Adults With Solid Tumors With a Focus on Hereditary or Sporadic, Locally Advanced or Metastatic Medullary Thyroid Cancer (MTC)
Status: TERMINATED
Conditions: Medullary Thyroid Carcinoma
Interventions: DRUG: Bortezomib|DRUG: Vandetanib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transfusion in Cardiac Valve Surgery
Status: NOT_YET_RECRUITING
Conditions: Cardiac Surgery With Cardiopulmonary Bypass|Valve Heart Disease
Interventions: OTHER: Restrictive Transfusion Strategy|OTHER: Liberal Transfusion Strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: OTHER
Clinical trial: Analgesic Efficacy and Safety of V116517 in Subjects With Moderate to Severe Chronic Pain Due to Postherpetic Neuralgia (PHN)
Status: COMPLETED
Conditions: Postherpetic Neuralgia|Pain
Interventions: DRUG: V116517 50-mg tablets|DRUG: V116517 30-mg tablets|DRUG: Pregabalin capsules|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: CD5024 1% [Ivermectin 1%] Cream Versus Metronidazole 0.75% Cream in Papulopustular Rosacea (PPR) Study
Status: COMPLETED
Conditions: Papulopustular Rosacea
Interventions: DRUG: Ivermectin 1% cream|DRUG: Metronidazole 0.75% cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Home-based Diabetes-Modified Behavioral Activation Treatment for Low Income Seniors With T2DM
Status: ACTIVE_NOT_RECRUITING
Conditions: Type 2 Diabetes
Interventions: BEHAVIORAL: Supportive Therapy (Control)|BEHAVIORAL: Home DM-BAT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Methionine PET/CT Studies In Patients With Cancer
Status: RECRUITING
Conditions: Brain Tumors and/or Solid Tumors Including|Brain Stem Glioma|High Grade CNS Tumors|Ependymoma|Medulloblastoma|Craniopharyngioma|Low Grade CNS Tumors|Hodgkin Lymphoma|Non Hodgkin Lymphoma|Ewing Sarcoma|Osteosarcoma|Rhabdomyosarcoma|Neuroblastoma|Other
Interventions: DRUG: Methionine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Phase 1 Clinical Trial to Evaluate the Safety and Anti-Tumor Activity of AB-201
Status: NOT_YET_RECRUITING
Conditions: Breast Cancer|Gastric Cancer|Gastroesophageal Junction Adenocarcinoma
Interventions: DRUG: AB-201|DRUG: Cyclophosphamide|DRUG: Fludarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT