pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Epoprostenol for Injection in Pulmonary Arterial Hypertension - Extension of AC-066A401
Status: COMPLETED
Conditions: Pulmonary Arterial Hypertension
Interventions: DRUG: ACT-385781A (Actelion Epoprostenol)|DRUG: Flolan®
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of RAS/MAPK Pathway Hyperactivation on Growth' and Bone' Profile of the RASopathies
Status: RECRUITING
Conditions: RASopathy|Costello Syndrome|Noonan Syndrome|Cardio-Facio-Cutaneous Syndrome
Interventions: DIAGNOSTIC_TEST: Diagnostic test
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Advanced Monitoring to Inform and Guide Perioperative Hemodynamic Optimization 1 (AMIGO-1) Study
Status: COMPLETED
Conditions: Intraoperative Fluid Management
Interventions: OTHER: Intraoperative Hemodynamic Algorithm|COMBINATION_PRODUCT: Usual hemodynamic management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Investigation Of The Interaction Of GSK961081 With Inhaled Beta-Agonist And Anti-Muscarinic Drugs.
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: 400 microgrammes GSK961081|DRUG: 1200 microgrammes GSK961081
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Repeating LiST for Refractory Non-bacterial Prostatitis/Pelvic Pain Syndrome
Status: UNKNOWN
Conditions: Chronic Prostatitis With Chronic Pelvic Pain Syndrome
Interventions: DEVICE: Dornier Aries 2 device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antibacterial Photodynamic Therapy in the Management of Peri-implantitis
Status: NOT_YET_RECRUITING
Conditions: Peri-Implantitis|Plaque, Dental
Interventions: DEVICE: Lumoral Treatment|PROCEDURE: Standard oral hygiene instructions|PROCEDURE: Scaling and root planing (SRP|PROCEDURE: surgical anti-infective peri-implantitis treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparision of Pharmacokinetics(PK) and Pharmacodynamics(PD) of Biocon Insulin R and Humulin® R
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: BIOLOGICAL: Biocon Insulin R|BIOLOGICAL: Humulin®R
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: The Effect of Art-Based Mandala on Mental Health in Bone Marrow Transplant Patients
Status: COMPLETED
Conditions: Mental Health|Bone Marrow Cancer|ART
Interventions: OTHER: art-based mandala application
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Essential Oil+ELA, Plaque and Gingivitis
Status: COMPLETED
Conditions: Dental Plaque|Gingivitis
Interventions: DRUG: Experimental: essential oils and ELA|OTHER: Placebo|OTHER: Water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Antibiotic Instillation in Appendicitis
Status: COMPLETED
Conditions: Complicated Appendicitis|Acute Appendicitis
Interventions: DRUG: Ceftriaxone|PROCEDURE: Intra-peritoneal Fluid Aspiration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Impact of Holding on Stress and Bonding in Mother-Infant Pairs During Therapeutic Hypothermia
Status: COMPLETED
Conditions: Hypoxic-Ischemic Encephalopathy|Neonatal Encephalopathy
Interventions: BEHAVIORAL: Holding|OTHER: Saliva collection|BEHAVIORAL: No Holding
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Adebrelimab Plus Cetuximab and Chemotherapy for Patients With RAS/BRAF Wild-Type Unresectable Liver Metastases Colorectal Cancer
Status: RECRUITING
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: Adebrelimab + Cetuximab+ Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: One Year Clinical Evaluation of E.Max Laminate Veneers With and Without Using Grape Seed Extract as a Natural Collagen Cross-linking Agent Before Bonding
Status: UNKNOWN
Conditions: Retention & Fracture of Emax Laminate Veneers
Interventions: OTHER: Grape seed extract
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Response of 13-valent Conjugate Pneumococcal Vaccine in Patients With End Stage Renal Disease
Status: COMPLETED
Conditions: End Stage Renal Disease
Interventions: BIOLOGICAL: 13-valent conjugate pneumococcal vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PCV-VG in Pediatric Laparoscopic Surgery
Status: RECRUITING
Conditions: Anesthesia Complication|Mechanical Ventilation Complication
Interventions: DEVICE: Mechanical Ventilation Mode
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: To Evaluate Eye Installation-Tear Free
Status: COMPLETED
Conditions: Sunscreening Agents
Interventions: DRUG: SPF 50 Y49 091 (BAY 987516)|DRUG: SPF 50 X15 158 (BAY 987516)|DRUG: SPF 50 X15 160 (BAY 987516)|DRUG: SPF 50 X57 162 (BAY 987516)|OTHER: J & J baby shampoo, X46 046 (control)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Impact of Photodynamic Therapy as an Adjunct to Non-surgical Periodontal Treatment on Clinical and Biochemical Parameters Among Patients Having Mild Rheumatoid Arthritis With Periodontitis
Status: COMPLETED
Conditions: Rheumatoid Arthritis|Chronic Periodontitis
Interventions: DEVICE: Methylene blue mediated Photodynamic therapy|PROCEDURE: Non-surgical periodontal therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intraoral Imaging at Clinical Crown Lengthening
Status: COMPLETED
Conditions: Dental Caries of Root Surface|Surgery
Interventions: PROCEDURE: CLP and 12 weeks waiting|PROCEDURE: Digital impression taken at surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: is Ultrasound-guided Foam Sclerotherapy a Cost-effective Alternate for Treatment of Varicose Veins?
Status: UNKNOWN
Conditions: Pain|Leg Edema|Cost Effectiveness|Cosmesis
Interventions: DRUG: Sodium Tetradecyl Sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Single Dose Study Of PF-06291874 In Healthy Adult Subjects
Status: TERMINATED
Conditions: Healthy
Interventions: DRUG: PF-06291874 or placebo|DRUG: PF-06291874 or Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: AIRWEIGHS: Investigating Obesity as a Susceptibility Factor for Air Pollution in Childhood Asthma
Status: ACTIVE_NOT_RECRUITING
Conditions: Asthma
Interventions: DEVICE: Active Air Purifier|DEVICE: Placebo Air Purifier
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Exploratory Evaluation of AR-42 Histone Deacetylase Inhibitor in the Treatment of Vestibular Schwannoma and Meningioma
Status: TERMINATED
Conditions: Vestibular Schwannoma|Meningioma|Acoustic Neuroma|Neurofibromatosis Type 2
Interventions: DRUG: AR-42
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Targeting CD19 and CD22 CAR-T Cells Immunotherapy in Patients With Relapsed or Refractory B Cell Lymphoma
Status: RECRUITING
Conditions: Lymphoma, B-Cell
Interventions: BIOLOGICAL: CD19-CD22 CAR-T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Proof-of-concept Study for the Combination BAY60-4552 / Vardenafil for the Treatment of Erectile Dysfunction Not Sufficiently Responsive to Standard Therapy With PDE5 Inhibitors
Status: COMPLETED
Conditions: Erectile Dysfunction
Interventions: DRUG: BAY60-4552 plus Vardenafil|DRUG: Vardenafil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Erythropoietin (Epo) and Venofer Trial After Autologous Hematopoietic Stem Cell Transplantation (HSCT)
Status: COMPLETED
Conditions: Hematological Malignancies
Interventions: DRUG: Darbepoetin alpha (Aranesp)|DRUG: Iron saccharate (Venofer)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study of TRUVIEW ART™(Advanced Reconstruction Tech)to Improve Image Quality on Chest Radiograph
Status: UNKNOWN
Conditions: Thoracic Diseases
Interventions: RADIATION: Chest x-ray image acquisition|RADIATION: Creation of TRUVIEW ART applied image|RADIATION: Comparison of TRUVIEW ART image with original image
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Preliminary Study Leading to Prevention of Pressure Ulcers by the Use of an On-board Device : Ergonomic Assessment of Wheelchair-seat Pressures in Spinal Cord Injured (SCI) Patients ( PRESDIE)
Status: COMPLETED
Conditions: Pressure Ulcer
Interventions: DEVICE: TexiMat
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Health-related Quality of Life of Patients With Esophageal Cancer After Surgery
Status: UNKNOWN
Conditions: Esophageal Cancer
Interventions: PROCEDURE: MIE|PROCEDURE: Three-incision thoracotomy|PROCEDURE: Ivor-Lewis esophagectomy|PROCEDURE: Sweet esophagectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Experiential Learning on Dietary Fiber Literacy
Status: COMPLETED
Conditions: Literacy|Bowel Symptoms
Interventions: OTHER: dietary fiber literacy|OTHER: routine care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Neurosurgery Recruitment Maneuver Study
Status: COMPLETED
Conditions: Subdural Pressure During Supratentorial Brain Tumour Resection
Interventions: PROCEDURE: Recruitment maneuver|PROCEDURE: Sham recruitment maneuver
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Verteporfin Photodynamic Therapy Administered in Conjunction With Ranibizumab in Patients With Subfoveal Choroidal Neovascularization Secondary to Age-related Macular Degeneration (AMD)
Status: TERMINATED
Conditions: Macular Degeneration|Choroidal Neovascularization
Interventions: DRUG: Verteporfin Photodynamic Therapy|DRUG: Ranibizumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intrathecal Dexamethasone and Labor Analgesia
Status: COMPLETED
Conditions: Effects of; Anesthesia, in Labor and Delivery
Interventions: DRUG: Dexamethasone|DRUG: Levobupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of the Effects of Bimatoprost and a Fixed Combination of Latanoprost and Timolol on 24-hour Blood and Ocular Perfusion Pressures
Status: COMPLETED
Conditions: Glaucoma
Interventions: DRUG: Bimatoprost|DRUG: Latanoprost/Timolol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dietary Salt in Postural Tachycardia Syndrome
Status: COMPLETED
Conditions: Postural Orthostatic Tachycardia Syndrome
Interventions: RADIATION: Blood Volume|RADIATION: Total Blood Volume|PROCEDURE: Exercise Capacity Test - Bicycle|PROCEDURE: Posture Study
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Low Exhaled NO and ICS in Suspected Asthma
Status: UNKNOWN
Conditions: Asthma
Interventions: DRUG: Budesonide (Pulmicort)|DRUG: Placebo - dummy inhaler
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Statins on IgG, IgA and IgM Level in Chronic Hemodialysis Patients
Status: COMPLETED
Conditions: Chronic Kidney Disease
Interventions: DRUG: Lipitor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of ALKS 4230 (Nemvaleukin Alfa) With Pembrolizumab in Head and Neck Cancer
Status: COMPLETED
Conditions: Non-cutaneous Squamous Cell Carcinoma of Head and Neck
Interventions: DRUG: ALKS 4230|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Low Dose Naltrexone Therapy in Children With Crohn's Disease
Status: COMPLETED
Conditions: Crohn's Disease
Interventions: DRUG: Naltrexone|OTHER: Placebo, sugar pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cisplatin-Epinephrine Injectable Gel Plus Paclitaxel and Carboplatin in Treating Patients With Recurrent Head and Neck Cancer
Status: UNKNOWN
Conditions: Head and Neck Cancer
Interventions: DRUG: carboplatin|DRUG: cisplatin-e therapeutic implant|DRUG: paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Activity and Safety of Front-line Venetoclax and Rituximab in Young and Fit Patients With Chronic Lymphocytic Leukemia
Status: COMPLETED
Conditions: Chronic Myeloid Leukemia
Interventions: DRUG: Venetoclax|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adherence and Preference of Continuous Positive Airway Pressure Versus Mandibular Advancement Splints in Obstructive Sleep Apnea Patients: A Randomized Trial
Status: COMPLETED
Conditions: Obstructive Sleep Apnea
Interventions: DEVICE: Positive Airway Pressure (PAP)|DEVICE: Mandibular Advancement Splints (MAS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Tolerability of BAF312 in Patients With Polymyositis
Status: TERMINATED
Conditions: Polymyositis
Interventions: DRUG: Placebo|DRUG: BAF312
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Contrast Nephropathy and Nitrates
Status: COMPLETED
Conditions: Contrast Induced Nephropathy
Interventions: DRUG: Intravenous Nitroglycerin|DRUG: IV Fluids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of ELI-002 in Subjects With KRAS Mutated Pancreatic Ductal Adenocarcinoma (PDAC) and Other Solid Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Minimal Residual Disease|KRAS G12D|KRAS G12R|NRAS G12D|NRAS G12R|Pancreatic Ductal Adenocarcinoma|Colorectal Cancer|Non-small Cell Lung Cancer|Ovarian Cancer|Cholangiocarcinoma|Bile Duct Cancer|Gallbladder Carcinoma
Interventions: DRUG: ELI-002 2P
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CHW Intervention to Improve Nutrition Security of Patients With Hypertension
Status: NOT_YET_RECRUITING
Conditions: Hypertension|Nutrition, Healthy|Food Insecurity|Community Health Worker
Interventions: BEHAVIORAL: Nutrition-enhanced CHW|BEHAVIORAL: Basic CHW
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Umbrella Study of Novel Anti-cancer Agents in Patients With NSCLC Who Progressed on an Anti-PD-1/PD-L1 Containing Therapy
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: Durvalumab|DRUG: AZD9150|DRUG: AZD6738|DRUG: Vistusertib|DRUG: Olaparib|DRUG: Oleclumab|DRUG: trastuzumab deruxtecan|DRUG: cediranib|DRUG: AZD6738 (ceralasertib)|DRUG: AZD6738 (ceralasertib)|DRUG: AZD6738 (ceralasertib) (240 mg or 160 mg)|DRUG: AZD6738 (ceralasertib) 7 days monotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Muscadine Grape Seed Supplementation and Vascular Function
Status: COMPLETED
Conditions: Dietary Supplements
Interventions: DIETARY_SUPPLEMENT: Muscadine grape seed supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: YOOMI: Effect of Gamified Physical Therapy Exercise Software on Inpatient Mobility
Status: RECRUITING
Conditions: Weakness, Muscle|Delirium in Old Age|Muscle Atrophy or Weakness|Muscle Loss|Hospital Acquired Condition|Physical Disability|Physical Inactivity
Interventions: DEVICE: Yoomi Physical Therapy Software
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Fish Oil vs. Placebo on Subjective Effects of Alcohol
Status: COMPLETED
Conditions: Alcohol Dependence
Interventions: DRUG: Fish Oil with ethanol and placebo ethanol infusions|DRUG: Placebo with ethanol and placebo ethanol infusions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Investigate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single Rising Doses of BI 187004 CL
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Placebo to BI 187004 CL|DRUG: BI 187004 CL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Neuromodulation of Lidocaine Cream Effect on Chronic Pain Patients
Status: RECRUITING
Conditions: Chronic Low Back Pain
Interventions: DEVICE: tDCS|OTHER: Lidocaine cream|OTHER: Control cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Safety of DAPSone as a Second-line Option in Adult Immune Thrombocytopenia
Status: UNKNOWN
Conditions: Adult Immune Thrombocytopenia (ITP)|Dapsone
Interventions: DRUG: Dapsone (Disulone®)|DRUG: Prednisone (Cortancyl®) alone followed by monitoring and "standard of care"|DRUG: Prednisone (Cortancyl®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Management of Oxaliplatin-related Gastroesophageal Variceal Bleeding
Status: UNKNOWN
Conditions: Gastroesophageal Varices Hemorrhage|Gastrointestinal Cancer|Received Oxaliplatin-based Chemotherapy
Interventions: PROCEDURE: Endoscopic treatment|PROCEDURE: TIPS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Granulocyte-Colony Stimulating Factor (G-CSF) as Optimizing Therapy for Pediatric Liver Transplantation
Status: COMPLETED
Conditions: Liver Cirrhosis|Severe Malnutrition|PELD|Undernutrition
Interventions: DRUG: G-CSF (Filgrastim)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Hemodynamic Effects of CGRP After Glibenclamide Administration in Healthy Volunteers
Status: COMPLETED
Conditions: Hemodynamics of Cranial Arteries|Headache|Cerebral Blood Flow
Interventions: DRUG: glibenclamide|DRUG: CGRP infusion|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Study of the Efficacy of PedyPhar® Ointment on the Diabetic Foot Ulcers
Status: TERMINATED
Conditions: Diabetic Foot Ulcer
Interventions: DRUG: Royal Jelly and Panthenol (PedyPhar® Ointment)|DRUG: Panthenol Ointment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Safety, Tolerability of Gefitinib as 1st Line in Caucasian Patients With EGFR Mutation Positive Advanced NSCLC
Status: COMPLETED
Conditions: Caucasian Patients With EGFR Mutation Positive Advanced NSCLC
Interventions: DRUG: Gefitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Increasing Motivation for Antiretroviral Therapy Initiation: A Pilot Intervention
Status: COMPLETED
Conditions: HIV
Interventions: BEHAVIORAL: Personal Approaches to Treatment Choices for HIV|BEHAVIORAL: Stress Reduction Skills Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating Efficacy and Safety of Elexacaftor/Tezacaftor/Ivacaftor in Subjects 6 Through 11 Years of Age With Cystic Fibrosis and F/MF Genotypes
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: ELX/TEZ/IVA|DRUG: IVA|OTHER: Placebo (matched to ELX/TEZ/IVA)|OTHER: Placebo (matched to IVA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating the Effect of Botulinum Toxin Type A on Semen Quality in Patients With Benign Prostatic Hyperplasia
Status: COMPLETED
Conditions: Benign Prostatic Hyperplasia
Interventions: BIOLOGICAL: Botulinum Toxin Type A|DRUG: Placebo (saline)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: How Effective is the Dose-graded Aerobic Training in Children Survivors of Acute Lymphoblastic Leukemia?
Status: COMPLETED
Conditions: Acute Lymphoblastic Leukemia
Interventions: OTHER: Dose-graded aerobic exercises|OTHER: Traditional physical rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fosaprepitant + 5HT3 Receptor Antagonists + Dexamethasone in Germ Cell Tumors
Status: COMPLETED
Conditions: Chemotherapy-Induced Nausea and Vomiting
Interventions: DRUG: Fosaprepitant|DRUG: Dexamethasone|DRUG: 5HT3
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Emollient 'Plus' vs Urea 10% for Mild-Moderate Atopic Dermatitis
Status: COMPLETED
Conditions: Dermatitis, Atopic
Interventions: OTHER: Aqua posae and microresyl|OTHER: Urea 10%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Relationship Between Microbiota and Prognosis of Hepatocellular Carcinoma(HCC) After Systemic Treatments
Status: ENROLLING_BY_INVITATION
Conditions: Liver Cancer|Microbiota|Adverse Event|Prognosis|Efficacy
Interventions: DIAGNOSTIC_TEST: questionnaire survey
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: MSP3-CRM-Vac4All/ Alhydrogel® Vaccine
Status: RECRUITING
Conditions: Malaria,Falciparum
Interventions: BIOLOGICAL: MSP3-CRM-Vac4All/ Alhydrogel®|BIOLOGICAL: Anti-Rabies Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Combined Transvenous and Epicardial Lead Placement Procedure for Implantation of Cardiac Resynchronization Devices: a Feasibility Study.
Status: UNKNOWN
Conditions: Heart Failure With Intraventricular Conduction Delay
Interventions: DEVICE: Hybrid CRT-D/P implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of CDP870 as Add-on Meditation to Methotrexate (MTX) in Patients With Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Placebo of CDP870|DRUG: CDP870 200mg|DRUG: Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Resistance Exercise Combined With Protein Supplementation in People With Pancreatic Cancer: The RE-BUILD Trial
Status: RECRUITING
Conditions: Pancreatic Cancer
Interventions: BEHAVIORAL: Resistance Training (RT) and Protein Supplementation (PS)|BEHAVIORAL: Resistance Training (RT)|BEHAVIORAL: Attention Control (AC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Therapeutic Exercise on the Psychological Well-being of Women Victims of Gender Violence.
Status: COMPLETED
Conditions: Anxiety Disorders|Depressive Symptoms|Gender-based Violence
Interventions: OTHER: Therapeutic exercise|OTHER: Therapeutic exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Validating the Use of Candin as a Challenge Agent in Healthy Participants - Intervention Specific Appendix 4
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Cosentyx|DRUG: Candin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Reactogenicity and Protectivity Following Measles- Rubella (MR) Routine Immunization in Indonesian Infants and Children
Status: COMPLETED
Conditions: Safety Issues|Immunogenicity
Interventions: BIOLOGICAL: Measles-Rubella (MR) Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of the Effectiveness of Xultophy® (Insulin Degludec/Liraglutide) in an Adult Real-world Population With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: insulin degludec/liraglutide
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Cultivated Stem Cell Transplantation for the Treatment of Limbal Stem Cell Deficiency
Status: UNKNOWN
Conditions: Limbal Stem Cell Deficiency
Interventions: PROCEDURE: Cultivated limbal stem cell graft transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dialysate Sodium Lowering Trial
Status: COMPLETED
Conditions: Hemodialysis Complication|Fluid Overload|Dialysis Disequilibrium|Intra-dialytic Hypotension|Hypertension
Interventions: OTHER: Dialysate Sodium Lowering
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Prophylactic Norepinephrine Infusion Combined With Colloid Coloading for Postspinal Anesthesia Hypotension
Status: COMPLETED
Conditions: Adverse Event
Interventions: DRUG: Normal saline|DRUG: Norepinephrine (0.025 μg/kg/min)|DRUG: Norepinephrine (0.05 μg/kg/min)|DRUG: Norepinephrine (0.075 μg/kg/min)|DRUG: Norepinephrine (0.1 μg/kg/min)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of BoneSeal® on Bone Hemostats in Patients Undergoing Cardiothoracic Surgery
Status: COMPLETED
Conditions: Coronary Artery Bypass Grafting
Interventions: DEVICE: BoneSeal|DEVICE: Ostene
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Cardioprotective Effects of Endogenous Erythropoietin in Patients Undergoing Coronary Artery Bypass Surgery
Status: COMPLETED
Conditions: Cardiac Surgery
Interventions: PROCEDURE: acute normovolemic hemodilution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Film Array Gastrointestinal Panel Compared to Usual Care for ED Evaluation of Infectious Diarrhea
Status: TERMINATED
Conditions: Infectious Diarrhea
Interventions: DIAGNOSTIC_TEST: Biofire Film Array Gastrointestinal Panel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: St. John's Wort in the Treatment of Raynaud's Phenomenon
Status: COMPLETED
Conditions: Raynaud's Disease
Interventions: DRUG: St. John's Wort|DRUG: Lactose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: This Study Was Conducted to Evaluate the Safety and Immunogenicity of IVACFLU-S Produced in Children From 6 Months to Under 18 Years Old and the Elderly Over 60 Years Old in Vietnam
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: IVACFLU-S
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of Effectiveness and Safety of Three Lock Solutions for Long-Term Central Venous Catheter for Hemodialysis
Status: COMPLETED
Conditions: Chronic Kidney Disease
Interventions: DRUG: Heparin Lock Solution|DRUG: Trissodium Citrate 30%|DRUG: Minocycline-EDTA 30 mg/ml - 3 mg/ml
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Examining the Active Ingredients of Consultation to Improve Implementation of a Parent-mediated Intervention for Children With Autism in the Community Mental Health System
Status: COMPLETED
Conditions: Autism Spectrum Disorder
Interventions: OTHER: Consultee-centered administrative consultation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: First-In-Human (FIH) Study of W0180 as Single Agent and in Combination With Pembrolizumab in Adults With Locally Advanced or Metastatic Solid Tumors
Status: TERMINATED
Conditions: Locally Advanced or Metastatic Solid Tumors
Interventions: BIOLOGICAL: W0180|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diagnostic Accuracy of CCTA-derived Versus AngiogRaphy-dErived QuantitativE Flow Ratio (CAREER) Study
Status: UNKNOWN
Conditions: Coronary Stenosis|Hemodynamics|Coronary Artery Disease|Coronary Computed Tomography Angiography
Interventions: DIAGNOSTIC_TEST: CT-QFR|DIAGNOSTIC_TEST: QFR|DIAGNOSTIC_TEST: FFR
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of TAK-071 in People With Parkinson Disease
Status: COMPLETED
Conditions: Parkinson Disease|Healthy Participants
Interventions: DRUG: TAK-071|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Injectable Collagen Scaffold™ Combined With MSCs Transplantation for Brain Injury
Status: UNKNOWN
Conditions: Brain Injury
Interventions: PROCEDURE: Stereotactic Hematoma Evacuation|BIOLOGICAL: MSCs Transplantation|BIOLOGICAL: Injectable Collagen Scaffold with MSCs Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ISCHEMIA-CTO Trial - Revascularisation or Optimal Medical Therapy of CTO
Status: RECRUITING
Conditions: Ischemic Heart Disease|Chronic Total Occlusion of Coronary Artery
Interventions: PROCEDURE: Percuteneous Coronary Intervention|OTHER: Optimal Medical Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Evaluate the Efficacy, Safety and Immunogenicity of QIVc in Subjects ≥2 to <18 Years of Age
Status: COMPLETED
Conditions: Influenza, Human
Interventions: BIOLOGICAL: QIVc|BIOLOGICAL: Non-influenza Comparator Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Intravitreal Conbercept for Idiopathic Choroidal Neovascularization
Status: UNKNOWN
Conditions: Idiopathic Choroidal Neovascularization
Interventions: DRUG: conbercept
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Music Listening as a Postanesthesia Care Unit (PACU) Nursing Intervention
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: BEHAVIORAL: Preferred music listening|BEHAVIORAL: Relaxation breathing narrative over hypnotic music listening
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I Study of Gene Induction Mediated by Sequential Decitabine/Depsipeptide Infusion With or Without Concurrent Celecoxib in Subjects With Pulmonary and Pleural Malignancies
Status: COMPLETED
Conditions: Advanced Esophageal Cancers|Primary Small Cell Lung Cancers|Non-Small-Cell Lung Carcinoma|Pleural Mesotheliomas|Cancers of Non-thoracic Origin With Metastases to the Lungs or Pleura
Interventions: DRUG: Decitabine|BIOLOGICAL: Depsipeptide|DRUG: Celecoxib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Validation of Quantitative Myocardial Tissue Characterization Through Non-gated CT
Status: RECRUITING
Conditions: Cardiac Disease|Covid19|Cardiotoxicity|Extracellular Space Alteration
Interventions: DIAGNOSTIC_TEST: Cardiac Magnetic Resonance|DIAGNOSTIC_TEST: Additional CT acquisition|DIAGNOSTIC_TEST: Blood tests
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: ctDNA-Directed Post-Hepatectomy Chemotherapy for Patients With Resectable Colorectal Liver Metastases
Status: RECRUITING
Conditions: Liver Metastases
Interventions: DRUG: Leucovorin|DRUG: 5-FLUOROURACIL|DRUG: Oxaliplatin|DRUG: Irinotecan|DRUG: Capecitabine|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Skeletal Muscle Function in Interstitial Lung Disease
Status: NOT_YET_RECRUITING
Conditions: Interstitial Lung Disease|Idiopathic Pulmonary Fibrosis|Hypersensitivity Pneumonitis|Scleroderma|Nonspecific Interstitial Pneumonia
Interventions: BIOLOGICAL: Hyperoxia
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect of Prophylactic Hemodialysis on the Morbidity and Mortality of the Patients With Chronic Kidney Disease Stages 3-4 Undergoing Coronary Artery Graft Bypass
Status: UNKNOWN
Conditions: Chronic Kidney Disease stage3|Chronic Kidney Disease stage4|Coronary Artery Disease
Interventions: PROCEDURE: hemodialysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Office-based Vision Therapy for Improving Reading and Attention in Children With Convergence Insufficiency
Status: UNKNOWN
Conditions: Convergence Insufficiency
Interventions: PROCEDURE: Office-based vergence/accommodative therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Efficacy, Quality of Life and Cost Effectiveness of Short-course Radiotherapy Followed by Capecitabine Plus Oxaliplatin chemotheRapy and TME for High-risk Rectal Cancer (ESCORT Trial)
Status: UNKNOWN
Conditions: Locally Advanced Rectal Cancer
Interventions: RADIATION: preoperative short-course radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A COMbined progRamme of Exercise and Dietary ADvice in mEn With Castrate Resistant Prostate Cancer
Status: COMPLETED
Conditions: Prostatic Neoplasms, Castration-Resistant|Prostate Cancer
Interventions: OTHER: Exercise Intervention|OTHER: standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Optimizing Vibrational Therapy to Improve Gait and Balance in Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: DEVICE: PDVibe2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Preservative-free Tafluprost/Timolol Fixed Combination: Morning vs Evening Dosing
Status: COMPLETED
Conditions: Glaucoma, Open-Angle
Interventions: DRUG: Tafluprost/timolol fixed combination
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Journey of Transformation Curriculum for Native American Adolescents
Status: TERMINATED
Conditions: Alcohol Use|Tobacco Use|Substance Use|Sexual Health
Interventions: BEHAVIORAL: Journey of Transformation-Native Youth Health Leadership Program curriculum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety & Efficacy of AlloRx SC® in PTHS Patients
Status: UNKNOWN
Conditions: Pitt Hopkins Syndrome
Interventions: BIOLOGICAL: AlloRx Stem Cells®|OTHER: Placebo control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Evaluate the Safety and Tolerability of Hydrogen in Patients With Parkinson's Disease
Status: TERMINATED
Conditions: Parkinson Disease
Interventions: DRUG: Hydrogen|DRUG: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: On Demand Contraception: Ulipristal Acetate Plus a COX-2 Inhibitor at Peak Fertility
Status: COMPLETED
Conditions: Contraception
Interventions: DRUG: Ulipristal Acetate 30 MG Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Defactinib and VS-6766 for the Treatment of Patients With Metastatic Uveal Melanoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Uveal Melanoma
Interventions: DRUG: Defactinib Hydrochloride|DRUG: Raf/MEK Inhibitor VS-6766|PROCEDURE: Biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate Efficacy and Safety of Weekly PEG-somatropin (GenSci004) in Treatment Naive Children With Growth Hormone Deficiency
Status: NOT_YET_RECRUITING
Conditions: GHD
Interventions: DRUG: GenSci004|DRUG: Genotropin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Relationship Between Immunity and Metabolism in Patients Receiving Immune Checkpoint Inhibitors for Advanced Cancer. ( RIMEC )
Status: ACTIVE_NOT_RECRUITING
Conditions: Metabolism Disorder|Cancer|Immune Checkpoint Inhibitors
Interventions: DIAGNOSTIC_TEST: calorimetry, impedance measurement at baseline and after 3 months of treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Investigate the Analgesic Efficacy of AZD2423 Compared With Placebo After 28 Days Treatment in Patients With Painful Diabetic Polyneuropathy
Status: COMPLETED
Conditions: Neuropathic Pain
Interventions: DRUG: AZD2423|DRUG: AZD2423|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immunoglobulin Replacement Therapy for Immunoglobulin G Subclass 2 Deficient Patients With Bronchiectasis
Status: WITHDRAWN
Conditions: Bronchiectasis|Immunoglobulin Subclass Deficiency
Interventions: DRUG: Cuvitru 20 % Injectable Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radiolabeled Monoclonal Antibody in Treating Patients With Glioblastoma Multiforme or Anaplastic Astrocytoma
Status: COMPLETED
Conditions: Brain and Central Nervous System Tumors
Interventions: PROCEDURE: conventional surgery|RADIATION: iodine I 131 monoclonal antibody TNT-1/B
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: How Stress Alters Opioid Drug Effects
Status: COMPLETED
Conditions: Motivation|Drug Effect|Stress Reaction|Misuse, Opioid
Interventions: DRUG: Oxycodone|DRUG: Placebo|BEHAVIORAL: Stress State Induction|BEHAVIORAL: Control State Induction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Medication Development in Alcoholism: Investigating Glucocorticoid Antagonists
Status: COMPLETED
Conditions: Alcoholism
Interventions: DRUG: Korlym (mifepristone)|DRUG: Sugar Pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Chest CT Using Low-concentration Iodine Contrast Media
Status: RECRUITING
Conditions: Pulmonary Disease
Interventions: DRUG: Iohexol (320mgI/mL) with 120kVp|DRUG: Iohexol (320mgI/mL) with 100kVp|DRUG: Iohexol (270mgI/mL) with 100kVp|DRUG: Iohexol (240mgI/mL) with 100kVp
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: The Effect of Urinating Through the Zipper or by Pulling Down the Trousers on Uroflowmetry Parameters in LUTS
Status: COMPLETED
Conditions: Benign Prostatic Hyperplasia|Micturition Disorder|Urinary Obstruction|Urinary Tract Disease|Urologic Diseases
Interventions: DIAGNOSTIC_TEST: position of urination
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Non-surgical Treatment of Carpal Tunnel Syndrome: Night Splint Versus Local Corticosteroid Infiltration
Status: UNKNOWN
Conditions: Carpal Tunnel Syndrome
Interventions: DRUG: betamethasone dipropionate, betamethasone disodium phosphate and lidocaine 2%|DEVICE: Wrist splinting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Mulligan Manual Therapy and Trunk Stabilization Exercises Versus Isometric Knee Strengthening on Knee Osteoarthritis
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: OTHER: Mulligan Joint mobilization|OTHER: Trunk stabilization group|OTHER: Knee strengthening group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Efficacy of ZD6126 in Combination With Oxaliplatin, 5-Fluorouracil and Leucovorin in Subjects With Metastatic Colorectal Cancer.
Status: TERMINATED
Conditions: Colorectal Neoplasms|Metastases, Neoplasm
Interventions: DRUG: ZD6126|DRUG: Placebo|DRUG: 5-fluorouracil|DRUG: leucovorin|DRUG: oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT