pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: The Pharmacodynamic/Pharmacokinetic Interaction of Tipranavir and Ritonavir With Loperamide in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Tipranavir|DRUG: Ritonavir|DRUG: Loperamide
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EMDR in Spider Phobia: Work Mechanisms and Treatment Outcome
Status: COMPLETED
Conditions: Spider Phobia
Interventions: BEHAVIORAL: Eye Movement Desensitization and Reprocessing Therapy|BEHAVIORAL: Virtual Reality Exposure Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endoscopic Treatment of Salivary Glands Affected by Sjögren's Syndrome
Status: UNKNOWN
Conditions: Sjögren's Syndrome
Interventions: PROCEDURE: Sialoendoscopy|DRUG: saline|DRUG: hydrocortisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of the Safety and Pharmacokinetics of XL765 (SAR245409) in Adults With Solid Tumors
Status: COMPLETED
Conditions: Cancer
Interventions: DRUG: XL765 (SAR245409)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Levofloxacin-based Concomitant Therapy for H. Pylori Eradication in Diabetic Patients
Status: COMPLETED
Conditions: Helicobacter Pylori Infection
Interventions: DRUG: Pantoprazole|DRUG: Amoxicillin|DRUG: Metronidazole|DRUG: Levofloxacin|DRUG: Clarithromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Study of Mirvetuximab Soravtansine (IMGN853) and Pembrolizumab in Endometrial Cancer (EC)
Status: ACTIVE_NOT_RECRUITING
Conditions: Endometrial Cancer
Interventions: DRUG: Pembrolizumab|DRUG: IMGN853
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chemoprevention Therapy in Treating Patients at High Risk of Developing Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma and Plasma Cell Neoplasm
Interventions: DRUG: clarithromycin|DRUG: prasterone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: The Effect of Reflexology on Lactation and Postpartum Comfort for Cesarean-delivery Primiparous Mothers
Status: COMPLETED
Conditions: Breastfeeding|Lactation Failure|Nursing Caries|Postpartum|Reflexology
Interventions: OTHER: Reflexology
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of LSD on Neuroplasticity in Healthy Subjects
Status: RECRUITING
Conditions: Healthy
Interventions: DRUG: Lysergic Acid Diethylamide|DRUG: Lysergic Acid Diethylamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Beta-Glucan on Cholesterol Lowering
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DIETARY_SUPPLEMENT: Control|DIETARY_SUPPLEMENT: 3g LMW beta-glucan|DIETARY_SUPPLEMENT: 5g LMW beta-glucan|DIETARY_SUPPLEMENT: 3g HMW beta-glucan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Pilot Study Utilising an Impression Technique to Capture in Vivo Images of Teeth
Status: COMPLETED
Conditions: Tooth Erosion
Interventions: OTHER: RS01|OTHER: Water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Improved Recovery by Iron Following Surgery With Blood Loss, the IRIS-trial
Status: NOT_YET_RECRUITING
Conditions: Surgery|Liver Metastases|Liver Cancer|Pancreas Cancer|Aortic Aneurysm
Interventions: DRUG: Ferric carboxymaltose|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Virtual Reality on Sleep Quality and Mental Well-being
Status: NOT_YET_RECRUITING
Conditions: Nursing Caries
Interventions: DEVICE: Occulus quest 2 virtual reality glasses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of Effectiveness of Alexander Technique Versus Feldenkrais Technique in Non - Specific Neck Pain Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Neck Pain
Interventions: DIAGNOSTIC_TEST: Alexander Technique (AT)|DIAGNOSTIC_TEST: Feldenkrais Technique (FT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: iADAPT: Off Label Use of Antipsychotics in the Nursing Home
Status: COMPLETED
Conditions: Off-label Use of Atypical Antipsychotic Drugs
Interventions: OTHER: Toolkit only with Web Access to Online Version|OTHER: Toolkit, Periodic Audit/Feedback, Educational Messages|OTHER: Items in Arm 2 plus Academic Detailing Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Liquid Meal Replacements in Conjunction With Lifestyle Intervention in Overweight Adolescents
Status: COMPLETED
Conditions: Overweight|Obesity
Interventions: BEHAVIORAL: weekly behavioral modification group|BEHAVIORAL: liquid meal replacements
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ExtraCorporeal Membrane Oxygenation in the Therapy of Cardiogenic Shock
Status: COMPLETED
Conditions: Cardiogenic Shock
Interventions: DEVICE: Veno-arterial extracorporeal membrane oxygenation (ECMO)|OTHER: Early conservative therapy according to standard practice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Jeuveau Treatment of Glabellar Lines Using OLD Versus COLD
Status: COMPLETED
Conditions: Glabellar Frown Lines
Interventions: DRUG: prabotulinumtoxinA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety of Dose Escalation in Definitive Hypofractionated Radiation Therapy With SPACEOAR TM for Patients With Low-to-intermediate Risk Localized Prostate Cancer (DESAR-L)
Status: RECRUITING
Conditions: Low-to-intermediate-risk Prostate Carcinoma
Interventions: RADIATION: Low- and medium-risk studies performed after biodegradable substance injection prostate cancer dose increase.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of PDT vs RFA vs PDT+RFA for the Treatment of Extrahepatic Cholangiocarcinoma
Status: RECRUITING
Conditions: Extrahepatic Cholangiocarcinoma|Bile Duct Cancer
Interventions: PROCEDURE: RFA|PROCEDURE: PDT|PROCEDURE: RFA combined with PDT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prevalence Study of Amyloidosis in Patients With Surgery of Suspect Bilateral Carpal Tunnel (AMYLYONCARP)
Status: RECRUITING
Conditions: Carpal Tunnel Syndrome Bilateral
Interventions: DIAGNOSTIC_TEST: tenosynovial tissue biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation of Ovarian Morphology and Function in Overweight Women During Weight Loss
Status: ACTIVE_NOT_RECRUITING
Conditions: Weight Loss|Anovulation|Amenorrhea|Infertility
Interventions: BEHAVIORAL: Commercial Weight Loss Program
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of Tirabrutinib (ONO-4059) in Patients With Primary Central Nervous System Lymphoma (PROSPECT Study)
Status: RECRUITING
Conditions: Refractory Primary Central Nervous System Lymphoma|Primary CNS Lymphoma
Interventions: DRUG: Tirabrutinib|DRUG: Tirabrutinib|DRUG: Tirabrutinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Validation of vFFR as Compared to FFR to Guide Revascularization of Non-culprit Lesions in STEMI Patients
Status: RECRUITING
Conditions: ST Elevation Myocardial Infarction|Multivessel Coronary Artery Disease|Percutaneous Coronary Intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Oxygen Portable Concentrator During Exercises in Patients With COPD
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DEVICE: Oxygen concentrators versus constant flow axygen|DEVICE: oxygen concentrator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Timing of CHolecystectomy In Severe PAncreatitis
Status: NOT_YET_RECRUITING
Conditions: Acute Pancreatitis|Cholelithiasis
Interventions: PROCEDURE: Laparoscopic cholecystectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Effectiveness of Financial Incentives and Nudges to Reduce Cellphone Use While Driving Among UBI Auto Policy Holders
Status: COMPLETED
Conditions: Automobile Accident
Interventions: BEHAVIORAL: Weekly feedback|BEHAVIORAL: End of intervention period incentive|BEHAVIORAL: Loss-framed weekly incentive
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Sonodynamic Therapy With ExAblate System in Glioblastoma Patients
Status: NOT_YET_RECRUITING
Conditions: Glioblastoma Multiforme
Interventions: DRUG: 5-Aminolevulinic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Amprenavir/Ritonavir or Saquinavir/Ritonavir in HIV-Infected Subjects Following Failure With Kaletra as Their Second Protease Inhibitor
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Amprenavir/ritonavir|DRUG: Saquinavir/ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MindEx: A Novel, Multifocal, Cognitive Brain-Machine Interface System
Status: NOT_YET_RECRUITING
Conditions: Paralysis; Quadriplegic
Interventions: DEVICE: Mind Extender (MindEx)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Parent-Child Memory Study: Improving Future Thinking Among Mothers
Status: RECRUITING
Conditions: Behavior, Health
Interventions: BEHAVIORAL: Episodic Future Thinking (EFT)|BEHAVIORAL: Episodic Recent Thinking (ERT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Hyaluronic Acid and Polynucleotides for Supra-bony Defects
Status: NOT_YET_RECRUITING
Conditions: Periodontal Diseases|Wound Heal|Periodontal Inflammation|Periodontal Pocket|Periodontal Attachment Loss
Interventions: COMBINATION_PRODUCT: Periodontal Access Flap (AF) + Combined Formulation of Hyaluronic acid and Polydeoxyribonucleotides (PNHA)|PROCEDURE: Periodontal Access Flap (AF)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Crystalloid Alone Versus Crystalloid Plus Colloid in Shock Resuscitation
Status: UNKNOWN
Conditions: Hypotension and Shock
Interventions: DRUG: Isotonic crystalloid solution resuscitation|DRUG: Colloid solution resuscitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BI 443651 Multiple Rising Dose in Healthy Volunteers Followed by a Cross-over in CF Subjects
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: BI 443651|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Variations of the Blood Pressure After Nephrectomy for Renal Cancer (VAPANCR)
Status: UNKNOWN
Conditions: Renal Cancer|Nephrectomy|Blood Pressure
Interventions: BIOLOGICAL: Renin measurement
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparison of NPH Insulin and Insulin Detemir in Children and Adolescents With Type 1 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 1
Interventions: DRUG: insulin detemir|DRUG: insulin NPH|DRUG: insulin aspart
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Outcomes in Mobile and Fixed-bearing Total Knee Arthroplasty
Status: UNKNOWN
Conditions: Osteoarthritis of Knee
Interventions: DEVICE: Mobile bearing|DEVICE: Fixed bearing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Role of Fenofibrate in Indirect Neonatal Hyperbilirubinemia: a Randomized Control Trial
Status: UNKNOWN
Conditions: Hyperbilirubinemia, Neonatal
Interventions: DRUG: Fenofibrate Capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Progressing TAAR-1, Dopamine, and Norepinephrine in Depression Using Solriamfetol
Status: RECRUITING
Conditions: Major Depressive Disorder
Interventions: DRUG: Solriamfetol 300 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pain With Trigger Finger Injection: A Comparison of Steroid Alone Versus Steroid/Lidocaine Mixture
Status: TERMINATED
Conditions: Trigger Finger Disorder
Interventions: DRUG: Dexamethasone Sodium Phosphate|DRUG: Xylocaine|DRUG: Sodium Chloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Compare Sudden Stopping and Weaning of Anticholinergics in Recurrence of OAB Symptoms
Status: COMPLETED
Conditions: Voiding Disorders
Interventions: DRUG: Solifenacin Succinate 5 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare Pharmacokinetics (PK) of Etrolizumab Administered Subcutaneously by a Prefilled Syringe With Needle Safety Device (PFS-NSD) or an Auto-injector (AI)
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Etrolizumab|DEVICE: Auto-Injector (AI)|DEVICE: Prefilled Syringe With Needle Safety Device (PFS-NSD)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Gait and Functional Improvement in Total Knee Arthroplasty With the Use of Verasense for Soft Tissue Balancing
Status: TERMINATED
Conditions: Osteoarthritis
Interventions: DEVICE: Sensor-assisted TKR (Verasense)|PROCEDURE: Control - Without the use of Verasense
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Compare a New Drug for Type 2 Diabetes to Placebo and to a Treatment Already Available for Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: LY2944876|DRUG: Exenatide extended-release|DRUG: Placebo|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial Evaluating External Evaluation and Training on the Incomplete Resection (POLIPEVA Study)
Status: RECRUITING
Conditions: Colonic Polyp|Colorectal Adenoma|Colorectal Cancer
Interventions: PROCEDURE: Colonic polypectomy|BEHAVIORAL: Online training course
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Osteopathic Treatment in Adult Patients With Cystic Fibrosis
Status: COMPLETED
Conditions: Cystic Fibrosis|Back Pain|Neck Pain|Chest Pain
Interventions: PROCEDURE: Osteopathic treatment|PROCEDURE: Sham Placebo|PROCEDURE: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of Haploidentical Stem Cell Transplantation for Haematological Cancers
Status: COMPLETED
Conditions: Hodgkin's Lymphoma|Non-Hodgkin's Lymphoma|Acute Myeloid Leukaemia|Acute Lymphoblastic Leukaemia|Myelodysplastic Syndrome|Chronic Myeloid Leukaemia|Chronic Lymphocytic Leukaemia|Acquired Bone Marrow Failure Syndromes|Other Haematological Malignancies; Unrelated HSCT Indicated
Interventions: PROCEDURE: Reduced intensity haplodentical stem cell transplant|PROCEDURE: Myeloablative haploidentical stem cell transplant
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Echocardiography Guided Fluid Resuscitation in Critically Ill Patients.
Status: COMPLETED
Conditions: Fluid Responsiveness|Echocardiography
Interventions: DEVICE: Echocardiography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Onartuzumab (MetMAb) in Combination With mFOLFOX6 in Patients With Metastatic Human Epidermal Growth Factor Receptor 2 (HER2) Negative Gastroesophageal Cancer
Status: COMPLETED
Conditions: Gastric Cancer
Interventions: DRUG: Placebo|DRUG: Onartuzumab (MetMAb)|DRUG: Oxaliplatin|DRUG: Folinic acid|DRUG: Levofolinic acid|DRUG: 5-Fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Long-term Benefit of Aortic Stent-graft in Patients With Distal Aortic Dissection
Status: TERMINATED
Conditions: Aortic Dissection|Aortic Aneurysm|Stent-graft
Interventions: PROCEDURE: Aortic stent-graft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating Bazedoxifene/Conjugated Estrogen Combinations in Symptoms Associated With Menopause
Status: COMPLETED
Conditions: Vasomotor Symptoms Associated With Menopause
Interventions: DRUG: Bazedoxifene/Conjugated Estrogen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Different Neural Blockade Techniques in Postoperative Analgesia After Total Hip Arthroplasty
Status: UNKNOWN
Conditions: Pain, Postoperative
Interventions: PROCEDURE: Fascia iliaca compartment block with IV-PCA|PROCEDURE: Femoral nerve block and lateral femoral cutaneous nerve with IV-PCA|PROCEDURE: IV-PCA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of ADHD With Atomoxetine in Children & Adolescents With ADHD & Comorbid Dyslexia
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder|Dyslexia
Interventions: DRUG: Atomoxetine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study of Loncastuximab Tesirine as Consolidation Strategy in Patients With LBCL in PR After CAR T-cell Therapy
Status: RECRUITING
Conditions: Large B-cell Lymphoma|Lymphoma
Interventions: DRUG: Loncastuximab Tesirine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Carbothera in the Treatment of Foot Ulcers
Status: UNKNOWN
Conditions: Critical Lower Limb Ischemia|Critical Limb Ischemia|Foot Ulcer|Skin Ulceration
Interventions: PROCEDURE: CO2-Enriched Tap Water (Carbothera)|PROCEDURE: Non-CO2-Enriched Tap Water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Managing Hypertension Among People Living With HIV
Status: RECRUITING
Conditions: Blood Pressure|Human Immunodeficiency Virus I Infection|Acquired Immunodeficiency Syndrome
Interventions: OTHER: Nurse-led Task-Shifting Strategy for Hypertension Control (TASSH) plus Practice Facilitation.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Phase I/IIa Clinical Evaluation of AllerT vs Placebo in Subjects Allergic to Birch Pollen
Status: TERMINATED
Conditions: Allergic Rhinitis|Allergy
Interventions: DRUG: AllerT SC|DRUG: AllerT ID|DRUG: Placebo SC|DRUG: Placebo ID
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vascutek Anaconda™ Abdominal Aortic Aneurysm (AAA) Post-Market Surveillance Registry
Status: TERMINATED
Conditions: Abdominal Aortic Aneurysm
Interventions: DEVICE: Vascutek Anaconda™ Stent Graft System
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: MRI Trial to exPlore the efficAcy and Safety of IMU-838 in Relapsing Remitting Multiple Sclerosis (EMPhASIS)
Status: ACTIVE_NOT_RECRUITING
Conditions: Relapsing-Remitting Multiple Sclerosis (RRMS)
Interventions: DRUG: IMU-838 (30 mg/day)|DRUG: IMU-838 (45 mg/day)|DRUG: Placebo|DRUG: IMU-838 (10 mg/day)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigating the Impact of the SGLT2 Inhibitor Empagliflozin on Postprandial Hypoglycaemia After Gastric Bypass
Status: COMPLETED
Conditions: Dumping Syndrome|Hypoglycemia, Reactive
Interventions: DRUG: Empagliflozin 25 MG|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cetuximab in Refractory Colorectal Cancer With K-RAS Mutated and Favorable FcγRIIa (CD32) Genotype
Status: COMPLETED
Conditions: Colorectal Neoplasms
Interventions: DRUG: Cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Ribociclib With Everolimus + Exemestane in HR+ HER2- Locally Advanced/Metastatic Breast Cancer Post Progression on CDK 4/6 Inhibitor.
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Ribociclib|DRUG: Everolimus|DRUG: Exemestane
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of METHoxyflurane on ANtiplatelet Effect of Ticagrelor in Patients With Unstable Angina Pectoris
Status: COMPLETED
Conditions: Unstable Angina
Interventions: DRUG: Ticagrelor followed with Methoxyflurane|DRUG: Ticagrelor followed with Morphine|DRUG: Ticagrelor alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Yttrium-90 Absorbed Doses Using PET/CT Versus PET/MR Imaging for Hepatic Malignancies
Status: COMPLETED
Conditions: Hepatic Malignancies
Interventions: DEVICE: PET/CT|DEVICE: PET/MR|RADIATION: SIRT with Y-90
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Transoral Retropterygoid Approach to Resect Recurrent Nasopharyngeal Carcinoma
Status: NOT_YET_RECRUITING
Conditions: Recurrent Nasopharyngeal Carcinoma
Interventions: PROCEDURE: endoscopic surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SkIn, Muscle and Bone Aging Determinants in HIV Infected-patients.
Status: COMPLETED
Conditions: HIV-1-infection|Marker; Structural
Interventions: PROCEDURE: DXA (dual-energy x-ray absorptiometric) measurement
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Innovative Treatments in Pneumonia (ITIP) 3
Status: COMPLETED
Conditions: Pneumonia
Interventions: DRUG: oral amoxicillin or parenteral ampicillin/ penicillin and gentamicin|DRUG: parenteral ampicillin/ penicillin|DRUG: gentamicin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Frequency of Cachexia in Ambulatory Cancer Patients and Psychological Burden in Patients and Their Primary Caregivers
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Malignant Solid Neoplasm|Caregiver|Metastatic Malignant Solid Neoplasm|Recurrent Leukemia|Recurrent Lymphoma|Recurrent Malignant Solid Neoplasm|Recurrent Plasma Cell Myeloma
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Albumin in Cardiac Surgery
Status: COMPLETED
Conditions: C.Surgical Procedure; Cardiac
Interventions: DRUG: Albumin solution|DRUG: Ringers acetate solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Oral Water on the Quality of Volume Expansion in Resuscitation Patients
Status: COMPLETED
Conditions: Intubated-ventilated Patients in the Intensive Care Unit
Interventions: OTHER: oral administration of water|OTHER: administration of saline solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: "UNMASKING Study" For Atrial Fibrillation Recurrences Typing in Early Postoperative Period
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: PROCEDURE: Circumferential PVI and subcutaneous cardiac monitor implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Novel Agents for Treatment of High-risk COVID-19 Positive Patients
Status: TERMINATED
Conditions: COVID|Sars-CoV2
Interventions: DRUG: Ivermectin|DRUG: Camostat Mesilate|DIETARY_SUPPLEMENT: Artemesia annua|DRUG: Artesunate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Pomegranate Juice on Oxidative Stress in Hemodialysis Patients
Status: COMPLETED
Conditions: End Stage Renal Disease|Hemodialysis
Interventions: DIETARY_SUPPLEMENT: Pomegranate juice|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: PREVENTION
Clinical trial: Midazolam Versus Dexamethasone-ondansetron in Preventing Postoperative Nausea-vomiting for Laparoscopic Surgeries
Status: COMPLETED
Conditions: Postoperative Nausea and Vomiting
Interventions: DRUG: Normal saline, Midazolam|DRUG: Dexamethasone, ondansetron
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Comparing Two Different Methods to Prescribe Exercise
Status: COMPLETED
Conditions: Physical Activity|Health Behavior
Interventions: BEHAVIORAL: A Randomized Controlled Trial Comparing the Physical Activity Guidelines for Americans to a New Method of Exercise Prescription Among College Students
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Comparison of Azelaic Acid 20 % Cream Versus Hydroquinone 4% Cream as an Adjuvant to Oral Tranexamic Acid in Melasma
Status: COMPLETED
Conditions: Melasma
Interventions: DRUG: Group A 4 % Hydroquinone Cream Topically and Oral Tranexamic Acid|DRUG: Group B Azelaic Acid 20 % Cream for 6 months
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety, Tolerability and Preliminary Efficacy Study of FRTX-02 Capsules in Healthy Subjects and Subjects With Atopic Dermatitis
Status: TERMINATED
Conditions: Atopic Dermatitis Eczema
Interventions: DRUG: FRTX-02 Capsule|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Lowering Dialysate Calcium Level on Progression of Coronary Artery Calcification and Bone Histomorphometry
Status: COMPLETED
Conditions: End-Stage Renal Disease|Hemodialysis
Interventions: DRUG: Low dialysate calcium|DRUG: high dialysate calcium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Adderall-XR for the Treatment of Adult Attention Deficit Hyperactivity Disorder and Cocaine Dependence
Status: COMPLETED
Conditions: Adult Attention Deficit Hyperactivity Disorder|Cocaine Dependence
Interventions: DRUG: Placebo|DRUG: Adderall-XR|DRUG: Adderall-XR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Personalized Support Using Instant Messaging Applications to Increase Smoking Cessation
Status: UNKNOWN
Conditions: Smoking Cessation
Interventions: BEHAVIORAL: AWARD advice|BEHAVIORAL: Health warning leaflet|BEHAVIORAL: Active referral to smoking cessation (SC) services|BEHAVIORAL: Regular messages through Instant Messaging (IM)|BEHAVIORAL: Psychosocial support and referral to SC services through IM|BEHAVIORAL: Message on general health delivered by short message service (SMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Epidemiology of Resistant Microbial Strains Among Different Groups of People (Healthy, Infected and Exposed to Animals)
Status: UNKNOWN
Conditions: ESBL Producing E.Coli|ESBL Producing K.Pneumoniae|Multidrug Resistant P.Aeruginosa|Carbapenem Resistant P.Aeruginosa|Methicillin Resistant Staphylococcus Aureus (MRSA)|Vancomycin (Glycopeptide) Resistant Enterococcus (VRE)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Extending Prostate Genetic Awareness, Navigation, and Delivery: The EXPAND Network
Status: RECRUITING
Conditions: Metastatic Prostate Carcinoma|Stage IIIB Prostate Cancer AJCC v8|Stage IIIC Prostate Cancer AJCC v8|Stage IV Prostate Cancer AJCC v8
Interventions: BEHAVIORAL: Training and Education|OTHER: Educational Intervention|PROCEDURE: Discussion
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: CPI-613 in Treating Patients With Advanced or Metastatic Bile Duct Cancer That Cannot Be Removed By Surgery
Status: COMPLETED
Conditions: Adult Primary Cholangiocellular Carcinoma|Advanced Adult Primary Liver Cancer|Cholangiocarcinoma of the Extrahepatic Bile Duct|Cholangiocarcinoma of the Gallbladder|Localized Unresectable Adult Primary Liver Cancer|Metastatic Extrahepatic Bile Duct Cancer|Recurrent Adult Primary Liver Cancer|Recurrent Extrahepatic Bile Duct Cancer|Unresectable Extrahepatic Bile Duct Cancer
Interventions: DRUG: 6,8-bis(benzylthio)octanoic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Metacognitive Self-regulated Learning and Sensory Integrative Approaches for Children With Autism Spectrum Disorders
Status: COMPLETED
Conditions: Autism Spectrum Disorder
Interventions: OTHER: Meta-cognitive self-regulated learning intervention|OTHER: Sensory integration intervention|OTHER: Activity-based intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Flunarizine Vs Amitriptyline in Prophylaxis of Migraine Prophylaxis
Status: NOT_YET_RECRUITING
Conditions: Migraine|Prophylaxis
Interventions: DRUG: Amitriptyline|DRUG: Flunarizine 5mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: SMART Clinical Study: Surgical Multi-center Assessment of RF Ablation for the Treatment of Vertebrogenic Back Pain
Status: COMPLETED
Conditions: Low Back Pain
Interventions: DEVICE: Intracept Treatment|DEVICE: Sham Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Allogeneic Cord Blood for Neurological Diseases in Adults
Status: NOT_YET_RECRUITING
Conditions: Neurological Diseases|Stroke|Spinal Cord Injuries
Interventions: BIOLOGICAL: Allogeneic cord blood treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Different COVID-19 Vaccine Combinations in Inducing Long-term Humoral Immunity [PRIBIVAC]
Status: UNKNOWN
Conditions: COVID-19
Interventions: BIOLOGICAL: Homologous mRNA booster vaccine|BIOLOGICAL: Heterologous mRNA booster vaccine|BIOLOGICAL: Non-mRNA booster vaccine A|BIOLOGICAL: Non-mRNA booster vaccine B|BIOLOGICAL: Non-mRNA booster vaccine C
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Systems Biology of Influenza A (H5N1) Virus Monovalent Vaccine With and Without Adjuvant System 03 (AS03)
Status: COMPLETED
Conditions: Influenza A Virus, H5N1 Subtype
Interventions: BIOLOGICAL: H5N1 vaccine plus AS03 adjuvant|BIOLOGICAL: H5N1 vaccine without adjuvant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Distal Protection Device in ST-elevation Myocardial Infarction (STEMI)
Status: COMPLETED
Conditions: ST-segment Elevation Myocardial Infarction
Interventions: DEVICE: distal protection and thrombus aspiration (The GuardWire Plus (Medtronic Inc.))|PROCEDURE: c-PCI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Randomized Trial of IVIg With or Without Cyclophosphamide in Pemphigus
Status: TERMINATED
Conditions: Pemphigus Vulgaris
Interventions: DRUG: intravenous immunoglobulin|DRUG: cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Contribution of Contrast Enhanced Ultrasound in the Diagnosis of Adnexal Torsion
Status: TERMINATED
Conditions: Adnexal Torsion
Interventions: DIAGNOSTIC_TEST: Contrast enhanced ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Prospective Randomized Trial Comparing Lichtenstein's Repair of Inguinal Hernia With Polypropylene Mesh Versus Surgisis
Status: COMPLETED
Conditions: Hernia, Inguinal
Interventions: DEVICE: Prolene Polypropylene Mesh|DEVICE: Surgisis Inguinal Hernia Matrix
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Proof of Concept of Remote Management of Chronic Inflammatory Airway Diseases for Patient Empowerment
Status: NOT_YET_RECRUITING
Conditions: Chronic Rhinosinusitis With Nasal Polyps|Asthma
Interventions: DEVICE: Radio Frequency IDentification (RFID) device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Effect of Platelet Rich Fibrin Matrix With and Without Peripheral Blood Mesenchymal Stem Cells on Implant Stability
Status: UNKNOWN
Conditions: Dental Implants
Interventions: BIOLOGICAL: Dental Implant with PRFM|BIOLOGICAL: Dental Implant with PRFM and PBMSCs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I Study Evaluating Safety, Tolerability, PK and PD of BL-8040 for Stem Cell Mobilization in Healthy Volunteers
Status: COMPLETED
Conditions: Mobilization of Hematopoietic Stem Cells (HSC) to Peripheral Blood (PB)
Interventions: DRUG: BL-8040|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Family History App in Personalized Medicine
Status: ACTIVE_NOT_RECRUITING
Conditions: Cancer, Breast|Cancer, Ovarian|Cancer, Colorectal|Cancer, Prostate|Melanoma|Coronary Artery Disease|Diabetes Mellitus, Type 2
Interventions: OTHER: FHAMe Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Apical Gap Length and Adaptation of Zirconia Post Using Intraoral and Extraoral Scan of Silicon Impression Technique
Status: NOT_YET_RECRUITING
Conditions: Endodontically Treated Teeth
Interventions: OTHER: Direct intra-oral scanning technique for the post space.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: The Clinical Impact of the Novel Alzheimer's Blood-based Biomarkers
Status: ENROLLING_BY_INVITATION
Conditions: Alzheimer Disease|Cognitive Impairment|Dementia|Neurodegenerative Diseases|Frontotemporal Dementia|Lewy Body Disease|Vascular Dementia
Interventions: DIAGNOSTIC_TEST: Early adoption of blood-based biomarkers for Alzheimer's disease
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Randomised, Controlled Comparison of Vitamin D Strategies is Acute Hip Fracture Patients
Status: COMPLETED
Conditions: Hip Fracture
Interventions: DRUG: Vitamin D2|DRUG: Vitamin D2|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Short Neoadjuvant Hemithoracic IMRT for MPM
Status: ACTIVE_NOT_RECRUITING
Conditions: Malignant Pleural Mesothelioma
Interventions: OTHER: Pre-op RT +/- chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Pharmacokinetics/Pharmacodynamics and Safety/Tolerability of Evogliptin in Hemodialysis Patients
Status: COMPLETED
Conditions: Hemodialysis Patients
Interventions: DRUG: Evogliptin 5mg|DRUG: Evogliptin 5mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: LCAR-T2C CAR-T Cells in Relapsed or Refractory CD4+ T-cell Lymphoma
Status: TERMINATED
Conditions: CD4+ T Lymphocyte Tumor (T Cell Lymphoma and T Cell Leukemia)
Interventions: DRUG: Efficacy of LCAR-T2C CAR-T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Intraoperative Volume Optimization on Outcome After Intrabdominal Surgery
Status: COMPLETED
Conditions: Hemodynamic Instability|Surgery
Interventions: OTHER: volume optimization|OTHER: standard volume administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Accurate WiFi-Based Localization of Dementia Patients For Caregiver Support:
Status: COMPLETED
Conditions: Dementia, Vascular|Alzheimer Dementia|Lewy Body Dementia With Behavioral Disturbance
Interventions: DEVICE: Activlink insole|OTHER: Activlink Phone Application
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Exercise for Memory Rehabilitation in Epilepsy
Status: RECRUITING
Conditions: Epilepsy, Generalized|Memory Impairment
Interventions: BEHAVIORAL: Supervised combined endurance and resistance training (CERT)|BEHAVIORAL: Delayed supervised combined endurance and resistance training (CERT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Functional Status Neutrophils in Rheumatoid Arthritis Patients to Identify New Biomarkers of Response to Anti-TNFalpha Therapy
Status: RECRUITING
Conditions: Rheumatoid Arthritis
Interventions: OTHER: Blood sampling
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Safety and Efficacy of the Tong-Fu-Xing-Shen Herbal Formula for Stroke-Associated Pneumonia
Status: UNKNOWN
Conditions: Stroke|Complication
Interventions: DRUG: Tongfu capsules|DRUG: The Placebo of Tongfu capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Position-Induced Opening of the Intervertebral Foramen is Efficient to Treat an Acute Lumbosacral Radiculopathy Caused by Disc Herniation
Status: COMPLETED
Conditions: Radiculopathy Lumbar|Disk Herniated Lumbar|Low Back Pain
Interventions: PROCEDURE: Physiotherapeutic, non-invasive position-induced opening of the intervertebral foramen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Manuel Pressure and Local Cold Spray in Reducing Injection Pain in Pregnant Women
Status: ACTIVE_NOT_RECRUITING
Conditions: Pain, Acute|Alloimmunisation in Pregnancy|Injection Site|Injection Fear
Interventions: OTHER: Cold Spray|OTHER: Manuel Pressure|OTHER: Standard Injection Procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Random-start Ovarian Stimulation in Egg-donors (ROSE)
Status: TERMINATED
Conditions: Infertility
Interventions: OTHER: Random start ovarian stimulation|DRUG: Gonadotrophins|DRUG: GnRH antagonist|DRUG: GnRH agonist
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Monotherapy-Controlled Study of Nifedipine Gastrointestinal Therapeutic System and Candesartan Cilexetil in Combination in Subjects With Essential Hypertension Inadequately Controlled on Candesartan Cilexetil
Status: WITHDRAWN
Conditions: Hypertension
Interventions: DRUG: Nifedipine GITS/Candesartan Cilexetil FDC(BAY98-7106)|DRUG: Nifedipine GITS/Candesartan Cilexetil FDC(BAY98-7106)|DRUG: Candesartan Cilexetil|DRUG: Candesartan matching placebo|DRUG: Nifedipine GITS/Candesartan Cilexetil FDC(BAY98-7106) 30/16mg matching placebo|DRUG: Nifedipine GITS/Candesartan Cilexetil FDC(BAY98-7106)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: RONICICLIB / Placebo in Combination With Chemotherapy in Small Cell Lung Cancer
Status: TERMINATED
Conditions: Small Cell Lung Carcinoma
Interventions: DRUG: Roniciclib (BAY1000394)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Lymphatic Massage on Lower Extremity Edema and Performance After Treadmill Exercise in Sprinter Compare to Static Stretching and Cold Water Immersion
Status: COMPLETED
Conditions: Post-exercise Lower Extremity Edema
Interventions: OTHER: Lymphatic massage|OTHER: Static stretching|OTHER: Cold water immersion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pneumococcal Nasopharyngeal Colonization as Predictor of Community-Acquired Pneumonia (CAP) in Adults With Chronic Diseases.
Status: UNKNOWN
Conditions: Streptococcus Pneumoniae Pneumonia|Streptococcus Pneumoniae Infection|Streptococcus Pneumoniae Infection Invasive|Community-acquired Pneumonia
Interventions: DIAGNOSTIC_TEST: nasopharyngeal aspirate
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: PROPHESYS 3: Observational Study on Predictors of Response in Patients With Treatment-naïve Chronic Hepatitis C Initiated on Treatment With Pegasys (Peginterferon Alfa-2a) or Peginterferon-alfa-2b
Status: COMPLETED
Conditions: Hepatitis C, Chronic
Interventions: DRUG: Peginterferon alfa-2a [Pegasys]|DRUG: Peginterferon alfa-2b [PegIntron®]
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p