pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: LSD-Perceptual-Choice-Study
Status: RECRUITING
Conditions: LSD Reaction
Interventions: DRUG: LSD 10 μg|DRUG: LSD 20 μg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Sleep and Endometrial Cancer
Status: TERMINATED
Conditions: Sleep|Endometrial Neoplasms|Pain
Interventions: DRUG: zolpidem|DRUG: sugar pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Phase I Clinical Study to Evaluate the Safety, Tolerability, and Efficacy of LCAR-M23, a CAR-T Cell Therapy Targeting MSLN in Patients With Relapsed and Refractory Epithelial Ovarian Cancer
Status: TERMINATED
Conditions: Epithelial Ovarian Cancer
Interventions: BIOLOGICAL: LCAR-M23 cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fingolimod in Treating Patients With Chemotherapy-Induced Neuropathy
Status: COMPLETED
Conditions: Chemotherapy-Induced Peripheral Neuropathy|Numbness|Pain|Tingling
Interventions: DRUG: Fingolimod|DRUG: Fingolimod Hydrochloride|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Laparoscopic Assisted Transanal Resection of Rectal Cancer With Total Mesorectal Excision
Status: UNKNOWN
Conditions: Rectal Cancer
Interventions: PROCEDURE: Laparoscopic Assisted Transanal Total Mesorectal Excision
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Treadmill Gait Training With Loading in Individuals With Stroke
Status: COMPLETED
Conditions: Stroke|Gait Disorders, Neurologic
Interventions: OTHER: Treadmill, ankle load|OTHER: Treadmill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Combined Respiratory Muscle Training and Steam Inhalation
Status: UNKNOWN
Conditions: Airway Obstruction|Asthma|COPD
Interventions: DEVICE: Respiratory muscle training with steam inhalation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Non-ablative Vaginal Erbium YAG Laser for the Treatment of Prolapse
Status: COMPLETED
Conditions: Prolapse
Interventions: PROCEDURE: Non-ablative vaginal Erbium YAG laser treatment|OTHER: Pelvic floor exercises (PFE)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Project Hope: Hospital Visit is an Opportunity for Prevention and Engagement With HIV-positive Crack Users
Status: COMPLETED
Conditions: HIV Infections|Crack Cocaine Use|Risky Sexual Behavior
Interventions: BEHAVIORAL: Prevention Care Advocate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Pharmacokinetics Study: Determination of Naproxcinod and Its Metabolites After Oral Administration in Male
Status: COMPLETED
Conditions: Pharmacokinetics
Interventions: DRUG: naproxcinod 750 bid|DRUG: naproxcinod 3000 mg od|DRUG: naproxen 500 mg bid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Safety of Elbasvir/Grazoprevir in Brazilian Participants With Chronic Hepatitis C Virus (HCV) Genotype 1 Infection With Advanced Fibrosis (F3 and F4)
Status: WITHDRAWN
Conditions: Hepatitis C
Interventions: DRUG: MK-5172A
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SP Intravenous Chemotherapy Versus SP by HIPEC in Stage Ⅲ Patients After D2 Gastrectomy
Status: UNKNOWN
Conditions: Stage Ⅲ Gastric Cancer
Interventions: DRUG: HIPEC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Role of Topically Dissolved Oxygen (TDO) to Ameliorate Signs of Photodamage
Status: COMPLETED
Conditions: Rosacea|Acne Vulgaris|Atopic Dermatitis|Seborrheic Dermatitis
Interventions: DRUG: Topical oxygen|DRUG: Topical oxygen|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Venoarterial PCO2 Difference /Arteriovenous O2 Content Difference Ratio as Goal of Early Septic Shock Therapy
Status: UNKNOWN
Conditions: Septic Shock
Interventions: PROCEDURE: volume resuscitation, vasoactive drug
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fluid Lavage of Open Wounds
Status: COMPLETED
Conditions: Open Fracture Wounds
Interventions: PROCEDURE: Saline Solution|PROCEDURE: Soap solution|PROCEDURE: Gravity Flow Irrigation|PROCEDURE: Low Pressure Irrigation|PROCEDURE: High Pressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Irbesartan on Endothelial Function of the Retinal Vasculature in Patients With Hypercholesterolemia
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DRUG: Irbesartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Narrative Exposure Therapy Versus Group Interpersonal Psychotherapy
Status: TERMINATED
Conditions: Posttraumatic Stress Disorder|Depression|Narrative Exposure Therapy|Interpersonal Psychotherapy
Interventions: BEHAVIORAL: Narrative Exposure Therapy|BEHAVIORAL: group IPT|OTHER: 6 months-baseline
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: |Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Long-Term Effects of Aortic Valve Mismatch
Status: COMPLETED
Conditions: THE LEFT VENTRICULAR REMODELING AFTER MECHANICAL AORTIC VALVE REPLACEMENT
Interventions: OTHER: exercise training|OTHER: subjects are asked to exercise during 20 or 30 minutes
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: An Extension Study of WA19926 of the Long-Term Safety of Tocilizumab (RoActemra/Actemra) in Patients With Early Moderate to Severe Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Tocilizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Pharmacokinetics and Efficacy of Paxalisib (GDC-0084) in Newly-diagnosed Glioblastoma
Status: COMPLETED
Conditions: Glioblastoma, Adult
Interventions: DRUG: Paxalisib (GDC-0084)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Arterio-venous ECMO on Severe Sepsis and ARDS
Status: COMPLETED
Conditions: Patients With Respiratory Failure and Shocked
Interventions: DRUG: Meropenem Injection|DEVICE: A-V ECMO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SCREENING
Clinical trial: Clifutinib Food Effect Study in Healthy Subjects
Status: COMPLETED
Conditions: Acute Myeloid Leukemia in Children
Interventions: DRUG: Clifutinib with fed state|DRUG: Clifutinib with fasted state
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Influence of Light Exposure on Cerebral MAO-A in Seasonal Affective Disorder and Healthy Controls Measured by PET
Status: COMPLETED
Conditions: Seasonal Affective Disorder
Interventions: OTHER: Light Therapy|OTHER: Placebo Light
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Randomized Phase II Study Of Bruton Tyrosine Kinase Inhibitor With Or Without Venetoclax In Veterans With Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL)
Status: NOT_YET_RECRUITING
Conditions: Chronic Lymphocytic Leukemia|Small Lymphocytic Lymphoma
Interventions: DRUG: Venetoclax|DRUG: Ibrutinib, Acalabrutinib, Zanubrutinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Omegaven (w-3 Fish Oil) Supplemented Parenteral Nutrition in Subjects of SICU.
Status: UNKNOWN
Conditions: Critical Ill Patients in SICU
Interventions: DRUG: Omegaven 10%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Remediation of Cognitive Dysfunction in Euthymic Bipolar Disorder Patients Using Transcranial Direct Current Stimulation (tDCS)
Status: COMPLETED
Conditions: Bipolar Disorder
Interventions: DEVICE: Transcranial direct current stimulation (Eldith DC Stimulator)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Relationship Between Left Ventricular Remodeling, Coronary Endothelial Function and Myocardial Fibrosis Using Positron Emission Tomography in Patients With ST-elevation Myocardial Infarction
Status: SUSPENDED
Conditions: ST Elevation Myocardial Infarction
Interventions: OTHER: (15)-O water positron emission tomography and Biomarkers
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Cryoablation With Vestibular Expansion for the Treatment of Paroxysmal/Short-course Persistent Atrial Fibrillation
Status: UNKNOWN
Conditions: Atrial Fibrillation
Interventions: DEVICE: cryoablation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intestinal Lavage for the Treatment of Severe C. Difficile Infections
Status: UNKNOWN
Conditions: Clostridium Difficile
Interventions: PROCEDURE: Intestinal Lavage|DRUG: Vancomycin|DRUG: PEG|DRUG: Metronidazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The S-CARE Trial: Manual Treatment for C-sections Scars, a Pilot Study.
Status: SUSPENDED
Conditions: Cesarean Section Complications|Cesarean Section; Complications, Wound, Infection (Following Delivery)
Interventions: OTHER: Osteopathic treatment|OTHER: Placebo treatment|OTHER: Self-massage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: " Endarterectomy Combined With Optimal Medical Therapy (OMT) vs OMT Alone in Patients With Asymptomatic Severe Atherosclerotic Carotid Artery Stenosis at Higher-than-average Risk of Ipsilateral Stroke "
Status: COMPLETED
Conditions: Asymptomatic Carotid Artery Stenosis
Interventions: OTHER: Carotid endarterectomy (CEA) combined with optimal medical therapy (OMT)|DRUG: Optimal medical therapy alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Influence of the Nebulizer on the Clinical Efficacy of Hypertonic Saline 3% in Children Aged Less Than 18 Months and Hospitalized With Acute Viral Bronchiolitis
Status: UNKNOWN
Conditions: Acute Viral Bronchiolitis
Interventions: DEVICE: nebulisations
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Therapeutic Efficacy Study of AL and DP in Western Kenya
Status: COMPLETED
Conditions: Malaria,Falciparum
Interventions: DRUG: Artemether-lumefantrine (AL)|DRUG: Dihydroartemisinin-piperaquine (DP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of a Ketogenic Diet on Psychological Outcomes
Status: COMPLETED
Conditions: Overweight|Mood|Appetitive Behavior
Interventions: OTHER: Mediterranean diet|OTHER: KEMEPHY|OTHER: KD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: FAST-A Study to Evaluate the Efficacy and Safety of Quetiapin IR in Patients With Acute Psychosis
Status: TERMINATED
Conditions: Psychotic Disorders|Schizophrenia|Bipolar Disorder
Interventions: DRUG: Quetiapine|PROCEDURE: Rating Scales|PROCEDURE: Self Assessment Form|PROCEDURE: Blood and urine samples|PROCEDURE: Sleeping pattern
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Evaluate the Effect of Food on the Pharmacokinetic Characteristics of HIP0901 Capsule
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: HIP0901 capsule (Fenofibric acid) Fasting conditions/ Fed conditions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Different Talocrural Joint Mobilization Techniques in Lateral Ankle Sprain
Status: COMPLETED
Conditions: Ankle Sprains|Ankle Injuries|Kinesiophobia|Jumping From Height
Interventions: OTHER: Single lep drop jump test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cottonseed Oil Versus Matched PUFA Effects
Status: NOT_YET_RECRUITING
Conditions: Dyslipidemia|Overweight and Obesity|Nutrition, Healthy
Interventions: OTHER: COTTONSEED OIL|OTHER: MATCHED PUFA DIET|OTHER: CONTROL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Requirement of Analgesics After Two Remifentanil Dosing Regimen in Cardiac Surgery.
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: remifentanil|DRUG: remifentanil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Peginterferon Alfa-2b in Chinese Chronic Hepatitis C Patients
Status: COMPLETED
Conditions: Chronic Hepatitis C
Interventions: DRUG: Ypeginterferon alfa-2b|DRUG: Pegasys|DRUG: Ypeginterferon alfa-2b|DRUG: Pegasys
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Study Between the Roles of Intrauterine Misoprostol Versus the Sublingual Route for Prevention of Postpartum Blood Loss in Elective Cesarean Sections
Status: COMPLETED
Conditions: Postpartum Hemorrhage
Interventions: DRUG: Misoprostol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Use of Antiretroviral (ARV) Drug Levels in Dried Blood Spots (DBS) to Assess and Manage ART Adherence in South Africa
Status: COMPLETED
Conditions: Therapeutic Adherence and Compliance
Interventions: BEHAVIORAL: Feedback on DBS Concentrations
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Role of Intraperitoneal Intraoperative Chemotherapy With Paclitaxel in the Surgical Treatment of Peritoneal Carcinomatosis From Ovarian Cancer. Hyperthermia Versus Normothermia
Status: COMPLETED
Conditions: Peritoneal Carcinomatosis
Interventions: DRUG: Paclitaxel|PROCEDURE: Radical surgery-peritonectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Analgesic Effect of Accelerated Repetitive Transcranial Magnetic Stimulation in Neuropathic Pain
Status: RECRUITING
Conditions: Peripheral Neuropathy
Interventions: DEVICE: Active repetitive transcranial magnetic stimulation|DEVICE: Sham repetitive transcranial magnetic stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Plasma Diurnal Variation in and Absorption of EPA and DHA
Status: COMPLETED
Conditions: Lipid Absorption and Metabolism
Interventions: DIETARY_SUPPLEMENT: Omega-3 oil: DHA enriched|DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: Omega-3 oil: EPA enriched
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Drug-Drug Interaction of Clomipramine HCl and Sildenafil Citrate in Healthy Males
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Treatment 1|DRUG: Treatment 2|DRUG: Treatment 3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Respiratory Training Protocols on GH Secretion in Obesity (ALRESPGHOB)
Status: TERMINATED
Conditions: Obesity
Interventions: OTHER: Rehabilitation protocol + guided spontaneous breathing exercises|OTHER: Rehabilitation protocol + specific respiratory muscle training program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Treating Chronic Pain in Buprenorphine Patients in Primary Care Settings
Status: COMPLETED
Conditions: Pain|Depression|Substance Use
Interventions: BEHAVIORAL: Treating Opioid Patients' Pain and Sadness (TOPPS)|BEHAVIORAL: Health Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of an Interactive Cognitive Support Tablet App to Improve the Management of Pediatric Cardiac Arrest
Status: COMPLETED
Conditions: Cardiac Arrest
Interventions: DEVICE: PediAppRREST|OTHER: AHA-PALS pocket reference card
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility of Therapy Integrating Peer-sharing, Technology, Aerobic and Resistance Training (TIPSTART)
Status: COMPLETED
Conditions: Group Meetings
Interventions: BEHAVIORAL: TIPSTART
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Cold Vapor on Sore Throat and Dysphagia in the Early Postoperative Period After Suspension Laryngoscopy
Status: UNKNOWN
Conditions: Sore Throat|Dysphagia|Surgery
Interventions: OTHER: Cold vapor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluation of the Safety and Efficacy of the Association of Ibrutinib and Daratumumab in Relapsed/Refractory Chronic Lymphocytic Leukemia With p53 Dysfunction
Status: ACTIVE_NOT_RECRUITING
Conditions: Relapsed or Refractory Chronic Lymphocytic Leukemia
Interventions: DRUG: Ibrutinib|DRUG: Daratumumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oxaliplatin in Treating Patients With Metastatic Breast Cancer
Status: COMPLETED
Conditions: Stage IV Breast Cancer
Interventions: RADIATION: carbon C 14 oxaliplatin|DRUG: oxaliplatin|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bacterial Translocation and Gut Microbiota in Type 1 Narcolepsy Patients Versus a Control Population
Status: NOT_YET_RECRUITING
Conditions: Narcolepsy Type 1|Bacterial Translocation
Interventions: OTHER: Blood sample|OTHER: Stool sample|OTHER: CSF sample
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Impact of Low Flow Nocturnal Oxygen Therapy on Hospital Admissions and Mortality in Patients With Heart Failure and Central Sleep Apnea
Status: TERMINATED
Conditions: Heart Failure|Central Sleep Apnea
Interventions: DRUG: Oxygen|OTHER: Room Air
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing the Efficacy of Two Methods for the Therapy of Uterine Adhesion
Status: UNKNOWN
Conditions: Intrauterine Adhesion
Interventions: PROCEDURE: dried biological amnion graft|DEVICE: disposable balloon uterine stent|DRUG: estradiol valerate tablets|DRUG: dydrogesterone Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study Comparing Anitocabtagene Autoleucel to Standard of Care Therapy in Participants With Relapsed/ Refractory Multiple Myeloma
Status: RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: Anitocabtagene Autoleucel|DRUG: Cyclophosphamide|DRUG: Fludarabine|DRUG: Pomalidomide|DRUG: Bortezomib|DRUG: Dexamethasone|DRUG: Daratumumab|DRUG: Carfilzomib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Activated Cytokine-induced Killer Armed With Bispecific Antibody for Advanced Pancreatic Cancer
Status: WITHDRAWN
Conditions: Advanced Pancreatic Cancer
Interventions: BIOLOGICAL: Activated CIK and CD3-MUC1 Bispecific Antibody in Treating Pancreatic Cancer|PROCEDURE: cryotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Antidepressant Effects on cAMP Specific Phosphodiesterase (PDE4) in Depressed Patients
Status: COMPLETED
Conditions: Major Depressive Disorder|Healthy
Interventions: PROCEDURE: PET scan|DRUG: Rolipram
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Ear Acupuncture to Improve Insomnia in Women With Breast Cancer
Status: COMPLETED
Conditions: Breast Neoplasm
Interventions: PROCEDURE: Ear acupuncture|BEHAVIORAL: Psychoeducation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Inactivity Duration on Lipid Metabolism
Status: ACTIVE_NOT_RECRUITING
Conditions: Metabolism
Interventions: BEHAVIORAL: 12 hours of physical inactivity|BEHAVIORAL: 24 hours of physical inactivity|BEHAVIORAL: 36 hours of physical inactivity
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: AED-delivery Using Drones in Out-of-hospital Cardiac Arrest
Status: COMPLETED
Conditions: Out-Of-Hospital Cardiac Arrest
Interventions: DEVICE: Automated flying Drone carrying an Automated external defibrillator (AED)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Comparison of Two Multi-Purpose Solution and Lens Material Combinations on Corneal Barrier Function
Status: COMPLETED
Conditions: Contact Lens Disinfecting Solutions
Interventions: DRUG: ProClear Lens Material soaked in ReNu Multiplus Multipurpose Solution|DRUG: Acuvue Advance Lens Material soaked in ReNu Multiplus Multipurpose Solution|DRUG: Acuvue Advance Lens Material soaked in Optifree RepleniSH Multipurpose Solution|DRUG: ProClear Lens Material soaked in Optifree RepleniSH Multipurpose Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Illness Management and Recovery (IMR) in Danish Community Mental Health Centres
Status: COMPLETED
Conditions: Schizophrenia|Bipolar Disorder
Interventions: BEHAVIORAL: Illness Management and Recovery (IMR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Statin Therapy on Muscle Mitochondrial Function and Aerobic Capacity
Status: COMPLETED
Conditions: Mitochondrial Diseases
Interventions: DRUG: Lipitor 20Mg Tablet|DRUG: Lipitor 80Mg Tablet|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: "Mamá, te Entiendo" App-based Intervention for Reducing Depressive Symptoms in Postpartum Women
Status: NOT_YET_RECRUITING
Conditions: Minor Depressive Disorder|Major Depressive Disorder|Post Partum Depression
Interventions: BEHAVIORAL: Mamá, te entiendo (Mom, I get you)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Homoeopathy and Physiotherapy in Chronic Low Back Pain Due to Osteoarthritis
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DRUG: Homeopathic complex and physiotherapy|DRUG: Placebo and physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness and Safety of Mesenchymal Stem Cell Therapy in Long COVID Patients
Status: RECRUITING
Conditions: Long COVID|Post-Acute COVID-19 Syndrome
Interventions: DRUG: umbilical cord mesenchymal stem cell
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Epidural and Paracostal Catheter Placement for Pain Control After Rib Fractures
Status: COMPLETED
Conditions: Rib Fractures|Wounds and Injuries
Interventions: OTHER: Thoracic epidural catheter placement|OTHER: Paracostal catheter placement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Incidence of HPV Infection and HPV-Associated Disease in Screening Indian Men Who Have Sex With HIV-Positive Men
Status: NOT_YET_RECRUITING
Conditions: HIV Infection|Human Papillomavirus Infection|Human Papillomavirus-Related Carcinoma
Interventions: OTHER: Cytology Specimen Collection Procedure|PROCEDURE: High Resolution Anoscopy with Biopsy|OTHER: Laboratory Biomarker Analysis|PROCEDURE: Medical Examination|PROCEDURE: Physical Examination|OTHER: Questionnaire Administration
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Assessing the Use of Nicotine Gum to Decrease Betel Nut Chewing in Saipan
Status: WITHDRAWN
Conditions: Betel Nut Cessation
Interventions: OTHER: Non-medicated gum|DRUG: NICOTINE 2MG GUM|DRUG: NICOTINE 4MG GUM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effects of Long-acting Methylphenidate on Academic Activity and Related Constructs in Children With ADHD
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: DRUG: Methylphenidate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nebulized Heparin for Prevention of Acute Lung Injury in Smoke Inhalation Injury
Status: COMPLETED
Conditions: Smoke Inhalation Injury|Acute Lung Injury
Interventions: DRUG: Heparin|OTHER: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Multiple-Dose Study To Evaluate The Pharmacokinetics And Safety Of Voriconazole In Immunocompromised Adolescents
Status: COMPLETED
Conditions: Pharmacokinetics
Interventions: DRUG: Voriconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Laparoscopic Tubal Disconnection Versus Laparoscopic Salpingectomy in Infertile Patients
Status: NOT_YET_RECRUITING
Conditions: Infertility, Female
Interventions: PROCEDURE: Laparoscopic tubal disconnection|PROCEDURE: Laparoscopic salpingectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Plant-protein Diets in Patients With Chronic Kidney Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Kidney Disease Stage 5
Interventions: OTHER: Plant-protein Diets|OTHER: Control Diets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ketamine and Magnesium in Erector Spinae Plane Block
Status: COMPLETED
Conditions: Postoperative Analgesia
Interventions: DRUG: Bupivacain|DRUG: Magnesium sulfate|DRUG: Ketamine Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pupil Dynamics and Color Vision for the Detection of Eye Diseases
Status: COMPLETED
Conditions: Retinitis Pigmentosa|Leber's Hereditary Optic Neuropathy|Stargardt Disease
Interventions: BEHAVIORAL: Dynamic pupillometry sessions
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Effect of Timing of Intravenous Paracetamol Administration on Post-surgical Pain
Status: UNKNOWN
Conditions: Obesity, Morbid
Interventions: DRUG: IV paracetamol|DRUG: IV saline (NaCl 0.9 %)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Percutaneous Needle Tenotomy (PNT) Versus Platelet Rich Plasma (PRP) With PNT in the Treatment of Chronic Tendinosis
Status: COMPLETED
Conditions: Chronic Tendinopathy
Interventions: PROCEDURE: PNT + PRP|PROCEDURE: PNT alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study of Efficacy and Safety of Investigational Treatments in Patients With Moderate to Severe Hidradenitis Suppurativa
Status: ACTIVE_NOT_RECRUITING
Conditions: Hidradenitis Suppurativa
Interventions: DRUG: CFZ533|DRUG: Placebo to CFZ533|DRUG: LYS006|DRUG: Placebo to LYS006|DRUG: MAS825|DRUG: Placebo to MAS825|DRUG: LOU064 25mg|DRUG: LOU064 100mg|DRUG: Placebo to LOU064|DRUG: VAY736|DRUG: Placebo to VAY736
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Oral Chinese Herbal Medicine for Psoriasis Vulgaris With Blood Stasis Syndrome
Status: UNKNOWN
Conditions: Psoriasis Vulgaris
Interventions: DRUG: Taodan Granules|DRUG: Taodan Granules Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ologen (OculusGen)-Glaucoma MMC Control Trial in India
Status: UNKNOWN
Conditions: Glaucoma
Interventions: DEVICE: OculusGen Biodegradable Collagen Matrix Implant|DRUG: Trabeculectomy with MMC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cold Snare Endoscopic Mucosal Resection (C-EMR) Versus Hot Snare Endoscopic Mucosal Resection (H-EMR) for Large Colorectal Polyps (10-20 mm)
Status: RECRUITING
Conditions: Polyps of Colon|Polyps|Polyp Intestine
Interventions: PROCEDURE: cold snare endoscopic mucosal resection (C-EMR)|PROCEDURE: Hot snare endoscopic mucosal resection (H-EMR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Psilocybin in Co-occuring Major Depressive Disorder and Borderline Personality Disorder
Status: RECRUITING
Conditions: Borderline Personality Disorder|Major Depressive Disorder
Interventions: DRUG: Psilocybin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Carfilzomib With Bendamustine and Dexamethasone in Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Bendamustine|DRUG: Carfilzomib|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Volume and Type of Fluid on Postoperative Incidence of Respiratory Complications and Outcome (CRC-Study)
Status: COMPLETED
Conditions: Respiratory Failure|Acute Respiratory Failure Requiring Reintubation|Pulmonary Edema|Pneumonia|Hypoxia|Acute Kidney Injury
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Fluid Management Study to Evaluate Changes in Intravascular Volume After Applying Various Pressure Levels on the Caval Vein
Status: COMPLETED
Conditions: Intravascular Volume|Respiratory Changes
Interventions: OTHER: Changes of difference in pulse pressure and plethysmography after applying various pressure levels on the caval vein
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Studying the Biology of IDH-mutant Gliomas Via Longitudinal Observation of 2-hydroxyglutarate (2-HG) Using MR Spectroscopy
Status: RECRUITING
Conditions: Glioma|Gliomas|High Grade Glioma|Malignant Glioma|Low Grade Glioma
Interventions: DEVICE: 3T MRI scanner
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Albumin-Bound Paclitaxel Combined With Antiangiogenic Agents in First-line Treatment of Relapsed or Metastatic TNBC
Status: RECRUITING
Conditions: Triple-negative Breast Cancer
Interventions: DRUG: Albumin-Bound Paclitaxel|DRUG: Apatinib Mesylate|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Neutralizing Antibody BGB-DXP593 in Participants With Mild-to-Moderate Coronavirus Disease 2019 (COVID-19)
Status: COMPLETED
Conditions: Covid19
Interventions: DRUG: BGB-DXP593|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Gonadotropin-releasing Hormone Agonist (GnRHa) in Ovarian Preservation in SLE Subjects Receiving Cyclophosphamide as Determined by Questionnaires
Status: RECRUITING
Conditions: Systemic Lupus Erythematosus (Sle)|Primary Ovarian Insufficiency (Poi)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Induction Chemotherapy Combined With Immunotherapy for Locally Advanced Hypopharyngeal Carcinoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Hypopharyngeal Carcinoma|Immunotherapy|Chemotherapy
Interventions: DRUG: Docetaxel|DRUG: Cisplatin|DRUG: Capecitabine|DRUG: Camrelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of PLX2853 in Relapsed or Refractory Acute Myeloid Leukemia or High Risk Myelodysplastic Syndrome
Status: COMPLETED
Conditions: Relapsed Acute Myeloid Leukemia (AML)|Refractory Acute Myeloid Leukemia (AML)|High-risk Myelodysplastic Syndrome (MDS)
Interventions: DRUG: PLX2853
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: FARE Augmentation of Proximal Femoral Fractures With CaS/HA and Systemic ZA
Status: RECRUITING
Conditions: Trochanteric Fracture of Femur|Osteoporotic Fracture of Femur|Hip Fractures|Bone Density, Low
Interventions: PROCEDURE: OSTEOSYNTHESIS|DRUG: Zoledronic acid|DEVICE: CERAMENT BONE VOID FILLER (BVF)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Effectiveness Study of Imiquimod Creams for the Treatment of Actinic Keratoses (AKs)
Status: COMPLETED
Conditions: Actinic Keratosis
Interventions: DRUG: Imiquimod cream|DRUG: Placebo cream|DRUG: Imiquimod cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transanal Versus Laparoscopic-assisted Transanal Through in the Management of Hirschsprung's Disease
Status: COMPLETED
Conditions: Pediatric Disorder|Hirschprung's Disease
Interventions: PROCEDURE: Group A: Pure transanal endorectal pull-through (TAERPT)|PROCEDURE: Group B: Laparoscopic-assistance endorectal pull-through (LAERPT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BTL-9000 High Frequency Therapy for the Waist Circumferential Reduction
Status: COMPLETED
Conditions: Circumferential Reduction|Waist Circumferential Reduction
Interventions: DEVICE: BTL-9000 HFT|DEVICE: sham BTL-9000 HFT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Safety and Immunogenicity of a Recombinant Trivalent Nanoparticle Influenza Vaccine With Matrix M-1 Adjuvant (NanoFlu)
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: NanoFlu|BIOLOGICAL: Fluzone HD - Day 0|BIOLOGICAL: Fluzone HD - Day 21|OTHER: Saline - Day 21
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: WTX-330 in Patients With Advanced or Metastatic Solid Tumors or Non-Hodgkin Lymphoma
Status: RECRUITING
Conditions: Advanced or Metastatic Solid Tumors|Non-Hodgkin Lymphoma
Interventions: DRUG: WTX-330
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized, Clinical Trial of Oral Midazolam Versus Oral Ketamine for Sedation During Laceration Repair.
Status: UNKNOWN
Conditions: Lacerations
Interventions: DRUG: Midazolam - active comparator|DRUG: Experimental Arm: Ketamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Angiotensin Converting Enzyme Inhibition in Children With Mitral Regurgitation
Status: TERMINATED
Conditions: Heart Defects, Congenital|Heart Septal Defects, Ventricular|Heart Failure, Congestive
Interventions: DRUG: Enalapril|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: FDG-PET and Circulating HPV in Patients With Cervical Cancer
Status: UNKNOWN
Conditions: Cervical Cancer
Interventions: PROCEDURE: Cervical swab|RADIATION: PET-CT|BIOLOGICAL: Plasma HPV
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Cryoballoon/Radiofrequency Ablation of Atrial Fibrillation Versus Medical Treatment for Heart
Status: NOT_YET_RECRUITING
Conditions: Atrial Fibrillation (AF)
Interventions: PROCEDURE: Catheter Ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Radiofrequency Splanchnic Denervation Versus Retrocrural Neurolytic Celiac Block for Pancreatic Cancer Pain
Status: UNKNOWN
Conditions: Chronic Pain
Interventions: PROCEDURE: radiofrequency splanchnic denervation|PROCEDURE: retrocrural celiac denervation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficiency and Cost-effectiveness of a Culturally Adopted Lifestyle Intervention Program - the MEDIM Study.
Status: COMPLETED
Conditions: Type 2 Diabetes|Impaired Glucose Tolerance|Obesity|Physical Activity
Interventions: BEHAVIORAL: Lifestyle intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Dalpiciclib in Combination With Exemestane and Trastuzumab Plus Pyrotinib in Early Triple Positive Breast Cancer
Status: RECRUITING
Conditions: Breast Cancer|Estrogen Receptor Positive Tumor|HER2-positive Breast Cancer
Interventions: DRUG: Trastuzumab Pyrotinib Exemestane Dalpiciclib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pushing and Manual Perineal Protection Techniques
Status: COMPLETED
Conditions: Perineal Tear|Episiotomy Extended by Laceration|Labor Complication
Interventions: PROCEDURE: Coached pushing and Finnish manual perineal protection|PROCEDURE: Uncoached pushing and Hands-poised perineal protection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Optically-guided Surgery in the Management of Early-staged Oral Cancer - COOLS TRIAL
Status: UNKNOWN
Conditions: Oral Cancer|High-grade Precancer
Interventions: PROCEDURE: Fluorescence visualization device|PROCEDURE: Fluorescence visualization device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Senofilcon A Lenses in Moderate to Severe Dry Eye Disease
Status: UNKNOWN
Conditions: Moderate to Severe Dry Eye Disease
Interventions: DEVICE: Senofilcon A contact lens
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Potential Harms of Untargeted Iron Supplementation in Cambodia Where Iron Deficiency is Not the Cause of Anemia
Status: COMPLETED
Conditions: Anemia, Iron Deficiency|Anemia|Intestinal Inflammation|Inflammation|Intestine; Complaints
Interventions: DIETARY_SUPPLEMENT: Ferrous sulfate|DIETARY_SUPPLEMENT: Ferrous Bisglycinate|DIETARY_SUPPLEMENT: Placebo of microcrystalline cellulose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Breast Milk Microbiota and Its Influence on the Development of Early and Late Neonatal Bacterial Sepsis Under Three Months of Age.
Status: RECRUITING
Conditions: Neonatal Sepsis
Interventions: OTHER: Collection of breast milk
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Adding Of Naxitamb In Induction Therapy For High Risk Neuroblastoma
Status: RECRUITING
Conditions: Neuroblastoma|GD2 Antibody (Naxitamab)
Interventions: DRUG: Addition of anti-GD2 immunotherapy (Naxitamab) at the stage of induction chemotherapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Physical Activity on Neurophysiologic Gene Expression Profiles of Chronic Low Back Pain
Status: COMPLETED
Conditions: Chronic Low Back Pain|Self-Management
Interventions: BEHAVIORAL: Problem-solving Pain to Enhance Living Well (PROPEL)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of Left Atrial Appendage Occlusion vs Standard Medical Therapy in Patients in AF Undergoing TAVI
Status: ACTIVE_NOT_RECRUITING
Conditions: Atrial Fibrillation|Aortic Stenosis
Interventions: DEVICE: LAAO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Capnography Feedback During Cardiopulmonary Resuscitation (CPR ) on Patient's Outcome
Status: COMPLETED
Conditions: Cardiopulmonary Arrest
Interventions: DEVICE: capnography feedback
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose:
Clinical trial: Gene Expression Profiles in Spinal Tuberculosis.
Status: RECRUITING
Conditions: Tuberculosis, Spinal|Tuberculosis, Osteoarticular|Tuberculosis|Mycobacterium Infections|Infections|Bone Diseases, Infectious|Musculoskeletal Diseases|Spinal Disease|Spondylitis|Spondylitis; Tuberculosis (Manifestation)|Spondylodiscitis|Positron-Emission Tomography|Diagnostic Imaging|Diagnostic Techniques and Procedures
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of Avastin (Bevacizumab) in Combination With Thoracic Radiation and Chemotherapy in Patients With Advanced Non-Squamous Non-Small Cell Lung Cancer.
Status: COMPLETED
Conditions: Non-Squamous Non-Small Cell Lung Cancer
Interventions: DRUG: bevacizumab [Avastin]|DRUG: cisplatin|DRUG: etoposide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT