pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Study in Participants With Type I Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: DRUG: Glargine|DRUG: LY2605541|DRUG: Insulin Lispro
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Chinese Herbal Formula Shu Yu Wan in Lung Cancer Patients
Status: WITHDRAWN
Conditions: Metastatic NSCLC
Interventions: DIETARY_SUPPLEMENT: Chinese herbs formula: Shu Yu Wan|OTHER: Placebo capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of a Plant-Based Diet in People With Monoclonal Gammopathy of Undetermined Significance (MGUS) or Smoldering Multiple Myeloma (SMM)
Status: ACTIVE_NOT_RECRUITING
Conditions: Monoclonal Gammopathy of Undetermined Significance|Smoldering Multiple Myeloma
Interventions: OTHER: Plant based meals
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Pentoxifylline and Zinc Co-administration in Patients With Oligoasthenoteratozoospermia
Status: UNKNOWN
Conditions: Idiopathic Infertility
Interventions: DRUG: Placebo|DRUG: Pentoxifylline|DRUG: zinc|DRUG: zinc + pentoxifylline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intra Arterial (IA) Steroids Infusion for Hepatic Acute Hepatic Graft Versus Host Disease (aGVHD)
Status: TERMINATED
Conditions: Acute Graft Versus Host Disease
Interventions: DRUG: Methylprednisolone (Intra-arterial continuous infusion of corticosteroids)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Clinical and Radiological Outcomes of the Use of Titanium Elastic Nail in The Fixation of Fresh Non-comminuted Fracture Mid-shaft Clavicle
Status: UNKNOWN
Conditions: Fracture Clavicle
Interventions: PROCEDURE: the Use of Titanium Elastic Nail in The Fixation of Fresh Non-comminuted Fracture Mid-shaft Clavicle
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intraventricular Transplantation of Mesenchymal Stem Cell in Patients With ALS
Status: WITHDRAWN
Conditions: Amyotrophic Lateral Sclerosis
Interventions: BIOLOGICAL: Intraventricular injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Project HERA (Health, Education, and Relationship-building for Adolescents- Moms and Tots)
Status: COMPLETED
Conditions: Child Behavior Problems|Parenting Skills|Obesity Prevention
Interventions: BEHAVIORAL: Combined parent training and obesity prevention program|BEHAVIORAL: Wellness program (active contact control)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Bean Polyphenols and Phytic Acid on Iron Absorption
Status: COMPLETED
Conditions: Blood Iron Isotope Enrichment
Interventions: OTHER: 586/8x87 white|OTHER: 586/8x87 brown|OTHER: BAT 881|OTHER: 586/8
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Discrete(TM) Safety Clinical Trial GLAD-01
Status: COMPLETED
Conditions: Safety and Tolerability in Healthy Volunteers
Interventions: DEVICE: Discrete(TM)|OTHER: Control Lactated Ringer's Solution (Control LRS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Clinical Study of the Aorta-femoral Bypass and Hybrid Intervention and the Iliac Arteries With Stenting and Plasty of the Common Femoral Artery Effectiveness in Patients With the Iliac Segment and Femoral Artery Occlusive Disease (TASC C, D)
Status: COMPLETED
Conditions: Atherosclerosis of the Peripheral Arteries
Interventions: PROCEDURE: Hybrid Intervention|PROCEDURE: Aorta femoral Bypass
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Intravenous L-Citrulline Influence on the Need for Invasive Mechanical Ventilation for Acute Hypoxemic Respiratory Failure in Patients With COVID-19
Status: COMPLETED
Conditions: Acute Hypoxemic Respiratory Failure
Interventions: DRUG: L-Citrulline|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Dietary Sodium Restriction of Improving Vascular Endothelial Function in Middle Aged and Older Adults
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Slow sodium tablets|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability of AGN-199201 in Patients With Erythema Associated With Rosacea
Status: COMPLETED
Conditions: Rosacea|Erythema
Interventions: DRUG: AGN-199201 Formulation A|DRUG: AGN-199201 Formulation B|DRUG: AGN-199201 Formulation C|DRUG: AGN-199201 Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Therapy With Sitagliptin and Lansoprazole to Restore Pancreatic Beta Cell Function in Recent-Onset Type 1 Diabetes
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: DRUG: Sitagliptin and Lansoprazole|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Orelabrutinib Plus R-CHOP in Treatment-naïve Patients With MCD Subtype Diffuse Large B-cell Lymphoma
Status: RECRUITING
Conditions: Diffuse Large B Cell Lymphoma (DLBCL)
Interventions: DRUG: Orelabrutinib + R-CHOP|DRUG: Placebo + R-CHOP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Continuous Monitoring of PtC02 on Ventilatory Weaning in Neuro-injured Patients
Status: UNKNOWN
Conditions: Acute Brain Injury
Interventions: DEVICE: TCM5 device (Radiometer) for PtC02 continuous measurement
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Feasibility and Effectiveness of Telehealth in Patients With Chronic Obstructive Pulmonary Disease in Taiwan
Status: UNKNOWN
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: OTHER: Telehealth program|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Development of an IDEAL Framework to Standardise Cytoreductive Surgery for Colorectal Peritoneal Metastases
Status: COMPLETED
Conditions: Colorectal Cancer Metastatic|Peritoneal Metastases
Interventions: PROCEDURE: Cytoreduction and Heated Intraperitoneal Surgery
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Comparative Study of Six Methods to Measure Human Contrast Vision
Status: UNKNOWN
Conditions: Methods to Measure Contrast Vision
Interventions: DEVICE: UCST-V1|DEVICE: UCST-V2|DEVICE: UCST-V3|DEVICE: Quick-CSF (QCSF)|DEVICE: Pelli-Robson|DEVICE: Optec 6500
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: FOLFOX6 Versus mFOLFIRINOX as First Line Chemotherapy in Metastatic Gastric Cancer or Esophagogastric Junction Adenocarcinoma (Type II-III)
Status: RECRUITING
Conditions: Gastric Carcinoma Stage IV|Esophagogastric Junction Adenocarcinoma Stage IV
Interventions: DRUG: Irinotecan|DRUG: Oxaliplatin|DRUG: 5-FU|DRUG: 5-FU|DRUG: Leucovorin|DRUG: 5-FU|DRUG: 5-FU
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Safety, Tolerability and Pharmacokinetics of Single and Repeat Doses of RV1729
Status: COMPLETED
Conditions: Asthma|Healthy Volunteers
Interventions: DRUG: RV1729 single dose|DRUG: RV1729 matching placebo single dose|DRUG: RV1729: 14 day repeat dose|DRUG: RV1729 matching placebo: 14 day repeat dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety/Efficacy Study of SGN-15 (Antibody-Drug Conjugate) Combined With Gemcitabine in Patients With Ovarian Cancer
Status: TERMINATED
Conditions: Ovarian Neoplasms
Interventions: DRUG: SGN-15 (cBR96-Doxorubicin Immunoconjugate)|DRUG: Gemzar (Gemcitabine)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Is Vitamin D2 Treatment-associated Decrease in 25(OH)D3 Level a Reciprocal Phenomena?
Status: COMPLETED
Conditions: Vitamin D Deficiency|25-Hydroxyvitamin D Concentration
Interventions: DRUG: Vitamin D3|DRUG: Vitamin D2|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Fecal Microbiota Transplantation (FMT) in the Management of Ulcerative Colitis (UC)
Status: COMPLETED
Conditions: Ulcerative Colitis
Interventions: BIOLOGICAL: Fecal Microbiota Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Pharmacokinetics of Single Rising Doses of YF476, a Gastrin Antagonist, in Healthy Men
Status: COMPLETED
Conditions: Reflux Oesophagitis
Interventions: DRUG: YF476
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Clinical Efficacy and Safety of Autologous Lung Stem Cell Transplantation in Patients With Idiopathic Pulmonary Fibrosis
Status: COMPLETED
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: BIOLOGICAL: Lung stem cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Baltimore Reading and Eye Disease Study
Status: COMPLETED
Conditions: Refractive Error|Visual Impairment|Convergence Insufficiency|Reading Disabilities
Interventions: BEHAVIORAL: Eyeglass wearing|BEHAVIORAL: Orthoptic exercises|OTHER: Specialist referral
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Combination Probiotic: BB-12 With LGG (Different Doses) in Treating Children With Autism Spectrum Disorder
Status: RECRUITING
Conditions: Autism Spectrum Disorder|Gastrointestinal Symptoms
Interventions: DRUG: BB-12 with LGG (Higher Dose)|DRUG: Placebo|DRUG: BB-12 with LGG (Lower Dose)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: TMS Treatment for Pain in Chronic Pancreatitis
Status: COMPLETED
Conditions: Idiopathic Chronic Pancreatitis|Pain
Interventions: DEVICE: Transcranial Magnetic Stimulation|DEVICE: Sham Transcranial Magnetic Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Adderall XR and Processing Speed in Multiple Sclerosis (MS)
Status: COMPLETED
Conditions: Impaired Processing Speed|Cognitive Impairment|Multiple Sclerosis
Interventions: DRUG: Adderall XR 5mg|DRUG: Adderall XR 10 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Proton Therapy in Adjuvant Pancreatic Cancer
Status: UNKNOWN
Conditions: Resected Pancreatic Adenocarcinoma
Interventions: DRUG: mFOLFIRINOX|RADIATION: Proton beam radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Holmium and Thulium Lasers With Ureteroscopy for Urinary Lithiasis
Status: UNKNOWN
Conditions: Renal Stone|Ureteral Stone
Interventions: DEVICE: Ureteroscopy for upper tract stone treatment with Holmium laser|DEVICE: Ureteroscopy for upper tract stone treatment with Thulium laser
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical Study of OR for Second-line Treatment of Refractory MZL
Status: RECRUITING
Conditions: OR Regimen for Relapsed/Refractory Marginal Zone Lymphoma
Interventions: DRUG: Orelabrutinib combined with rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Memory and MRI Changes With Hippocampus Avoidance Prophylactic Cranial Irradiation(HA-PCI) for Small Cell Lung Cancer(SCLC)
Status: UNKNOWN
Conditions: Small Cell Lung Cancer
Interventions: RADIATION: hippocampus avoidance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Timing on Efficacy of Morphine Analgesia After 2-chloroprocaine Anesthesia
Status: COMPLETED
Conditions: Labor|Analgesia, Epidural
Interventions: DRUG: Morphine-CP-saline (MCS)|DRUG: saline-2CP-morphine (SCM)|DRUG: saline-lidocaine-morphine (SLM)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Prevent Rash in People Starting Alpelisib for the Treatment of Breast Cancer
Status: TERMINATED
Conditions: Breast Cancer
Interventions: DRUG: Benralizumab|DRUG: fulvestrant or AIs) and PI3K inhibition (alpelisib)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of JW-100 and EUCRISA for the Treatment of Atopic Dermatitis
Status: WITHDRAWN
Conditions: Atopic Dermatitis
Interventions: OTHER: JW-100|DRUG: Eucrisa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Role of Roflumilast in Ulcerative Colitis
Status: NOT_YET_RECRUITING
Conditions: Ulcerative Colitis
Interventions: DRUG: Roflumilast 500 Ug ORAL TABLET [Daliresp]|DRUG: corticosteroids +immune suppressive +amino salicylic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hepatitis Vaccination in HIV Infection: Role of Adjuvant Interleukin-2
Status: UNKNOWN
Conditions: HIV Infections|Hepatitis A|Hepatitis B
Interventions: BIOLOGICAL: Twinrix|BIOLOGICAL: interleukin-2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Topical Glyceryl Trinitrate (GTN) and Eccentric Exercises in the Treatment of Midportion Achilles Tendinopathy
Status: COMPLETED
Conditions: Tendinopathy|Achilles Tendon Pain
Interventions: DRUG: glyceryl trinitrate|OTHER: Placebo ointment|OTHER: Eccentric exercise program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Neurocognitive Functioning in Patients With Newly Diagnosed Upper Aerodigestive Tract Cancer Receiving Treatment at Henry-Joyce Cancer Clinic
Status: COMPLETED
Conditions: Neurocognitive Impairment|Delirium|Esophageal Cancer|Head and Neck Cancer|Lung Cancer
Interventions: OTHER: Assessment of therapy complications|OTHER: Neurocognitive assessment|OTHER: Quality-of-life assessment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Fluorescence-navigated Thoracoscopy for Pulmonary Segmentectomy
Status: UNKNOWN
Conditions: Pulmonary Segmentectomy
Interventions: PROCEDURE: Indocyanine Green Injection through Peripheral Vein
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Surface Roughness of Heat Cured Acrylic Resin Versus Acrylic Resin With Titanium Dioxide
Status: UNKNOWN
Conditions: Denture Stomatitis
Interventions: OTHER: Titanium dioxide denture|OTHER: Rapid heat denture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Ziv-aflibercept in Ocular Disease Requiring Anti-VEGF Injection
Status: UNKNOWN
Conditions: Neovascularization|Macular Degeneration|Diabetic Retinopathy|Retinal Vein Occlusion|Choroidal Neovascularization|Retinal Neovascularization|Recurrent Pterygium|Cystoid Macular Edema
Interventions: DRUG: ziv-aflibercept
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Co Administration of GnRH Agonist and hCG for Final Oocyte Maturation
Status: COMPLETED
Conditions: Infertility
Interventions: DRUG: Buseralin|OTHER: Placebo|DRUG: pregnyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cardiac Computed Tomography (CT) Scan Compared to Transesophageal Echocardiogram (TEE) in Endocarditis
Status: TERMINATED
Conditions: Endocarditis
Interventions: PROCEDURE: CT Scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: A 4-Day Study to Evaluate the Photoxicity of Diacerein 1% Topical Ointment in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Diacerein 1% ointment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Comparison Between Oral Melatonin and Hydroxyzine in Pediatric Patients Undergoing Adenotonsillectomy
Status: RECRUITING
Conditions: Effect of Drug|Anxiety
Interventions: DRUG: Melatonin 3 MG|DRUG: Hydroxyzine Pill|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Empagliflozin and Hepatic Glucose Metabolism
Status: COMPLETED
Conditions: Hepatic Glucose Metabolism
Interventions: DRUG: Empagliflozin 25 MG|DRUG: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study to Compare the Safety and Efficacy of CMB305 With Atezolizumab to Atezolizumab Alone in Participants With Sarcoma (IMDZ-C232/V943A-002)
Status: TERMINATED
Conditions: Sarcoma|Myxoid/Round Cell Liposarcoma|Synovial Sarcoma|Metastatic Sarcoma|Recurrent Adult Soft Tissue Sarcoma|Locally Advanced Sarcoma|Liposarcoma
Interventions: BIOLOGICAL: CMB305|BIOLOGICAL: atezolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cluster Randomized, Parallel-group, Prospective, Follow-up Effectiveness Study in Kenyan Children 6-35 Months
Status: COMPLETED
Conditions: Stunting
Interventions: DIETARY_SUPPLEMENT: Intervention (integrated package)|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of Tarceva (Erlotinib) in Patients With Locally Advanced, Metastatic or Recurrent Non-Small Cell Cancer Who Present Epidermal Growth Factor Receptor Mutations
Status: COMPLETED
Conditions: Non-Squamous Non-Small Cell Lung Cancer
Interventions: DRUG: erlotinib [Tarceva]
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Ciclesonide Versus Budesonide in Patients With Asthma (18 to 75 y) (BY9010/M1-136)
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Ciclesonide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Ingenol Mebutate Gel 0.06% When Applied Once Daily for 2, 3 or 4 Consecutive Days to a Treatment Area of Approximately 250 cm2 on Trunk and Extremities in Subjects With Actinic Keratosis
Status: COMPLETED
Conditions: Actinic Keratosis
Interventions: DRUG: ingenol mebutate|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Interventions for Reading Disabilities in NF1
Status: RECRUITING
Conditions: Neurofibromatosis Type 1|Learning Disability|Reading Disability|NF1
Interventions: DRUG: Lovastatin|BEHAVIORAL: reading tutoring intervention|DRUG: Placebo Oral Tablet|BEHAVIORAL: Other Academic "sham" tutoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Behavioral Science Aspects of Rapid Test Acceptance
Status: COMPLETED
Conditions: HIV|Hepatitis C|Hepatitis B|Syphilis
Interventions: DEVICE: Rapid tests for HIV, HCV, HBV, and syphilis|DEVICE: HIV/HCV|DEVICE: HIV/syphilis|DEVICE: HIV only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Assessment of Chimerism and Relapse Post Bone Marrow/Hematopoietic Cell Transplant (HCT) Using AlloHeme Test
Status: RECRUITING
Conditions: Acute Myeloid Leukemia|Acute Lymphoblastic Leukemia|Myelodysplastic Syndrome
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Bone Microcirculation After Extracorporeal Shock Wave Therapy
Status: COMPLETED
Conditions: Intact Scaphoid Bone|Intact Metacarpal Bone|Fractured Scaphoid Bone|Fractured Metacarpal Bone
Interventions: DEVICE: Extracorporeal Shock Wave Therapy (Device Name: PiezoWave)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Remote Ischemic Conditioning and Atrial Fibrillation After Coronary Artery Bypass Grafting (CABG)
Status: TERMINATED
Conditions: Atrial Fibrillation
Interventions: PROCEDURE: Remote ischemic conditioning|PROCEDURE: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study to Evaluate the Safety, Tolerability, Efficacy, and PK of FHL-301 in Parkinson's Disease Patients.
Status: NOT_YET_RECRUITING
Conditions: Parkinson Disease
Interventions: DRUG: Gemfibrozil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of New Protocols in the Treatment of Upper Limb Dysfunctions in Patients With Cerebral Palsy
Status: COMPLETED
Conditions: Cerebral Palsy
Interventions: DEVICE: SES|DEVICE: VCT|DEVICE: VRCIT|DEVICE: traditional rehabilitation program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of AFO Heel Height and Stiffness on Gait
Status: RECRUITING
Conditions: Musculoskeletal Injury|Musculoskeletal Diseases|Peripheral Nervous System Diseases
Interventions: DEVICE: Tall Soft|DEVICE: Tall Firm|DEVICE: Short Soft|DEVICE: Short Firm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety and Preliminary Efficacy of Allogeneic Endothelial Progenitor Cells (EPCs) in Patients With Acute Ischemic Stroke
Status: NOT_YET_RECRUITING
Conditions: Acute Ischemic Stroke
Interventions: DRUG: iEPCs|COMBINATION_PRODUCT: Clinical standard treatment (CST)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Short-Term Dual Antiplatelet and Maintenance CloPidogrel Therapy After Drug-Eluting Stent Implantation
Status: TERMINATED
Conditions: Coronary Artery Disease
Interventions: DRUG: Clopidogrel|DRUG: Aspirin plus clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of TQB2450 Injection Combined With Anlotinib Hydrochloride Capsule in Subjects With Advanced Endometrial Cancer
Status: UNKNOWN
Conditions: Advanced Endometrial Cancer
Interventions: DRUG: TQB2450|DRUG: Anlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Clinical Evaluation of the RHEA Vital Sign Vigilance System in Hospital Patients
Status: COMPLETED
Conditions: Vital Sign Monitoring
Interventions: DEVICE: The Rhea Vital Sign Vigilance Device Group|DEVICE: The Earlysense System Device Group
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: The Influence of Smoking Status on Prasugrel and Clopidogrel Treated Subjects Taking Aspirin and Having Stable Coronary Artery Disease
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DRUG: Prasugrel|DRUG: Clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Repetitive Transcranial Magnetic Stimulation in Obese People With BED
Status: COMPLETED
Conditions: Binge Eating|Obesity
Interventions: DEVICE: TMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prevalence of Age Related Macular Degeneration (ARMD) in Parkinson's Patients and Assesment of the Role of L-DOPA
Status: COMPLETED
Conditions: Parkinson Disease|Age Related Macular Degeneration
Interventions: DIAGNOSTIC_TEST: Color retinography|DIAGNOSTIC_TEST: Optical coherence tomography|DIAGNOSTIC_TEST: Fundus autofluorescence imaging
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Beneficial Effects of Lactobacillus Reuteri DSM 17938 Supplementation on Asthmatic Children
Status: COMPLETED
Conditions: Airways Allergic Inflammation of Asthmatic Children
Interventions: DIETARY_SUPPLEMENT: Antileukotrienes + Lactobacillus reuteri|DIETARY_SUPPLEMENT: Antileukotrienes + Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Conditions With Open Label-Anecortave Acetate Sterile Suspension ( 15mg.) Where Lesions do Not Meet Acceptable Criteria for Standard Care.
Status: COMPLETED
Conditions: Age-Related Macular Degenerations.|Subfoveal Neovascularization.
Interventions: DRUG: Anecortave Acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 1 TAK-925 Study in Healthy Adult and Elderly Volunteers and Participants With Narcolepsy
Status: COMPLETED
Conditions: Healthy Participants and Patients With Narcolepsy
Interventions: DRUG: TAK-925|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Transcranial Direct Current Stimulation for Dysphagia Therapy in Acute Stroke Patients
Status: COMPLETED
Conditions: Stroke|Dysphagia
Interventions: DEVICE: Transcranial direct current stimulation|DEVICE: Sham stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Antiplatelet Therapy Guided by Thrombelastography in Patients With Acute Coronary Syndromes (TEGCOR Study)
Status: TERMINATED
Conditions: Thrombosis|Coronary Artery Disease
Interventions: DRUG: Prasugrel|DRUG: Clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study of ABT-263 in Combination With Rituximab in Lymphoid Cancers
Status: ACTIVE_NOT_RECRUITING
Conditions: CD20-Positive Lymphoid Malignancies|Chronic Lymphoid Leukemia|Hematological Malignancies|Non-Hodgkin's Lymphoma
Interventions: DRUG: rituximab|DRUG: ABT-263
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Computed Tomography Arteriograms (CTA) Volume Dose Reduction Study
Status: COMPLETED
Conditions: Aortic Aneurysm|Contrast Induced Nephropathy|Aortic and Arterial Anomalies
Interventions: DRUG: Low Dose Contrast (Omnipaque) 40mL|DRUG: Low Dose Contrast (Omnipaque) 50 mL
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Randomized Clinical Trial of Intranasal Dexamethasone as an Adjuvant in Patients With COVID-19
Status: COMPLETED
Conditions: Covid19
Interventions: DRUG: IV Dexamethasone|DRUG: Nasal Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Efficacy, PK, Immunogenicity and Safety of Wilate in Severe Von Willebrand Disease VWD) Patients <6 Years of Age
Status: ACTIVE_NOT_RECRUITING
Conditions: Von Willebrand Disease
Interventions: DRUG: wilate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Remote Ischemic PreConditioning in Off-pump Versus On-pump Coronary Artery Bypass Grafting(RIPCON)
Status: UNKNOWN
Conditions: Myocardial Injury
Interventions: PROCEDURE: Remote ischemic preconditioning (RIPC)|PROCEDURE: Coronary artery bypass grafting (CABG) without remote ischemic preconditioning protocol|PROCEDURE: Off-pump Coronary artery bypass surgery without remote ischemic preconditioning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Nasal CPAP Versus NIPPV On Diaphragm Electrical Activity (Edi) In VLBW Preterm Infants
Status: RECRUITING
Conditions: Preterm Birth|Premature Lungs|Respiratory Distress Syndrome in Premature Infant
Interventions: OTHER: Alternating traditional CPAP, NIPPV, and high CPAP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Investigate the Safety and Tolerability of Ziftomenib in Combination With Venetoclax/Azacitidine, Venetoclax, or 7+3 in Patients With AML
Status: RECRUITING
Conditions: Acute Myeloid Leukemia|Mixed Lineage Acute Leukemia|Mixed Lineage Leukemia Gene Mutation|Mixed Phenotype Acute Leukemia|Refractory AML|AML With Mutated NPM1|Acute Myeloid Leukemia Recurrent|Acute Myeloid Leukemia, in Relapse|NPM1 Mutation|KMT2Ar|Myeloid Sarcoma
Interventions: DRUG: Ziftomenib|DRUG: Venetoclax|DRUG: Azacitidine|DRUG: Daunorubicin|DRUG: Cytarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Guanfacine to Improve Substance Use Outcomes in Women
Status: COMPLETED
Conditions: Substance Use Disorders
Interventions: DRUG: Guanfacine|OTHER: Behavioral Counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: High Dose, Absorbed Dose Adjusted 90Y-ibritumomab With Peripheral Blood Stem Cells (PBSC) Support in B-cell Lymphoma
Status: COMPLETED
Conditions: B-cell Lymphoma
Interventions: DRUG: 90Y-ibritumomab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Armodafinil on Neurocognition and Cognitive Fatigue in Multiple Sclerosis (MS)
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DRUG: armodafinil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transanal Endoscopic Microsurgery Versus Endoscopic Submucosal Dissection For Large Rectal Adenomas
Status: WITHDRAWN
Conditions: RECTAL NEOPLASMS
Interventions: PROCEDURE: TEM - Transanal Endoscopic Microsurgery|PROCEDURE: ESD - Endoscopic Submucosal Dissection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: FNB in Meniscal Tear Under GA
Status: NOT_YET_RECRUITING
Conditions: Meniscus Tear|Femoral Nerve Block
Interventions: PROCEDURE: Sono-guided injection|DRUG: Ropivacaine injection|DRUG: Saline injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Diaphragmatic Pacemaker in Tetraplegic Patients With Spinal Cord Injuries
Status: COMPLETED
Conditions: Respiratory Paralysis|Diaphragmatic Paralysis|Spinal Cord Injury
Interventions: DEVICE: NeuRx RA/4 diaphragmatic pacemaker
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Agile Development of a Digital Exposure Treatment for Youth With Chronic Musculoskeletal Pain
Status: RECRUITING
Conditions: Chronic Pain|Exposure|Adolescent Behavior|Child Behavior
Interventions: BEHAVIORAL: Graded exposure treatment (GET)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I Study to Evaluate the Safety, Reactogenicity, and Humoral Immune Responses to an Inactivated H5N1 Influenza Vaccine
Status: COMPLETED
Conditions: Bird Flu|Avian Influenza|Influenza A(H5N1)
Interventions: BIOLOGICAL: AT-301
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study to Evaluate the Effect of GBT440 on TCD in Pediatrics With Sickle Cell Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Sickle Cell Disease
Interventions: DRUG: Voxelotor|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Micrometastases in Axillary Lymph Nodes in Breast Cancer, Post-neoadjuvant Chemotherapy
Status: COMPLETED
Conditions: Micrometastases|Neoadjuvant Chemotherapy
Interventions: PROCEDURE: Sentinel lymph node biopsy, axillary lymph node dissection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pilot Randomized Clinical Study of the Iliac Arteries and Common Femoral Artery With Stenting and the Iliac Arteries With Stenting and Plasty of the Common Femoral Artery
Status: UNKNOWN
Conditions: Atherosclerosis of the Peripheral Arteries
Interventions: PROCEDURE: Iliac segment recanalization and stenting Iliac segment Common Femoral Artery (CFA)|PROCEDURE: Iliac segment recanalization, stenting and plastic Common Femoral Artery (CFA) patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Performance and Safety Evaluation of MD-Shoulder Collagen Medical Device in the Treatment of Rotator Cuff Syndrome
Status: RECRUITING
Conditions: Rotator Cuff Tendinitis|Syndrome Rotator Cuff|Tendinopathy|Tendinoses, Rotator Cuff|Rotator Cuff Injuries
Interventions: DEVICE: MD-Shoulder Collagen Medical Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pain Catastrophizing and Routine Assessment of Patient Index Data 3(RAPID3) in Ten Categories of Rheumatology Outpatients
Status: COMPLETED
Conditions: Arthritis, Rheumatoid|Spondyloarthritis|Inflammatory Rheumatisms|Systemic Disorders
Interventions: OTHER: questionnaires
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Prospective Cohort of Transitional Urology Patients
Status: RECRUITING
Conditions: Spina Bifida|Myelomeningocele|Meningocele|Bladder Exstrophy|Genitourinary Congenital Anomalies|Cloacal Exstrophy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Gastroesophageal Reflux Disease (GERD)/Nighttime Heartburn and Driving Performance
Status: COMPLETED
Conditions: GERD
Interventions: DRUG: esomeprazole 40 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Evaluation of the Three-Seeds Mixture Treatment in Chronic Obstructive Pulmonary Disease Patients
Status: UNKNOWN
Conditions: Cough
Interventions: DIETARY_SUPPLEMENT: Three-seeds mixture|DIETARY_SUPPLEMENT: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Description and Prognostic Evaluation of Four Biological Parameters of Blast Cells in Adult Acute Lymphoblastic Leukemia
Status: UNKNOWN
Conditions: Adult Acute Lymphoblastic Leukemia
Interventions: PROCEDURE: DNA Index|PROCEDURE: S-Phase%|PROCEDURE: CD45 expression|PROCEDURE: P16 metabolic way
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of CAD-1883 for Spinocerebellar Ataxia
Status: WITHDRAWN
Conditions: Spinocerebellar Ataxias|Spinocerebellar Ataxia Type 1|Spinocerebellar Ataxia Type 2|Spinocerebellar Ataxia Type 3|Spinocerebellar Ataxia Type 6|Spinocerebellar Ataxia Type 7|Spinocerebellar Ataxia Type 8|Spinocerebellar Ataxia Type 10|Spinocerebellar Ataxia Type 17|ARCA1 - Autosomal Recessive Cerebellar Ataxia Type 1
Interventions: DRUG: CAD-1883|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Plant Exosomes and Patients Diagnosed With Polycystic Ovary Syndrome (PCOS) 17
Status: WITHDRAWN
Conditions: Polycystic Ovary Syndrome
Interventions: OTHER: Ginger exosomes|OTHER: Aloe exosomes|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Occlusal Relationship Assesment of Monolithic Zirconia FDPs
Status: COMPLETED
Conditions: Tooth-loss
Interventions: OTHER: Monolithic FDPs: before adjustment|OTHER: Monolithic FDPs: after adjustment|OTHER: Metal fused porcelain FDPs: before adjustment|OTHER: Metal fused porcelain FDPs: after adjustment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Breathing and Decision-Making
Status: RECRUITING
Conditions: Quality of Life|Behavior|Stress, Psychological
Interventions: BEHAVIORAL: Breathing with prolonged exhalation (ProlEx) during risky decision-making|BEHAVIORAL: Normal breathing (Eupnea/Control) during risky decision-making
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Phase III Study of the Effect of GTx-024 on Muscle Wasting in Patients With Non-Small Cell Lung Cancer (NSCLC)
Status: COMPLETED
Conditions: Muscle Wasting|Non Small Cell Lung Cancer
Interventions: DRUG: GTx-024|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Music During the Reduction of Distal Radius Fractures as an Adjunctive Therapy for Pain and Anxiety Management.
Status: RECRUITING
Conditions: Distal Radius Fracture Reduction
Interventions: DEVICE: No Music|DEVICE: Music
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Prediction of Erosive Disease in Early Rheumatoid Arthritis (RA) by Ultrasound and Cartilage Biodegradation Markers
Status: UNKNOWN
Conditions: Erosive Disease in Early Rheumatoid Arthritis
Interventions: PROCEDURE: Venipuncture, ultrasound, MRI, x-ray
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety and Efficacy of KPI-121 Compared to Placebo in Subjects With Dry Eye Disease
Status: COMPLETED
Conditions: Dry Eye Syndromes|Keratoconjunctivitis Sicca
Interventions: DRUG: KPI-121 0.25% Ophthalmic Suspension|DRUG: Vehicle of KPI-121 0.25% Ophthalmic Suspension
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Validity and Reliability of The 3-Meter Backward Walk Test in Individuals With Lower Limb Amputation
Status: COMPLETED
Conditions: Lower Limb Amputation Knee|Lower Limb Amputation Below Knee (Injury)
Interventions: DIAGNOSTIC_TEST: 3 meter backward walk test
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effects of High Protein Diet on Muscle Mass, Strength, and Physical Performance in Postmenopausal Women
Status: COMPLETED
Conditions: Muscle Loss|Physical Disability
Interventions: OTHER: High Protein Diet|OTHER: Control Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effectiveness and Safety Study of Pentosan Polysulfate Sodium for the Treatment of Interstitial Cystitis
Status: TERMINATED
Conditions: Interstitial Cystitis
Interventions: DRUG: Pentosan polysulfate sodium 100 mg|DRUG: Placebo|DRUG: Pentosan polysulfate sodium 100 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Stress Urinary Incontinence in Women With Autologous Adipose-derived Mesenchymal Stem Cells
Status: COMPLETED
Conditions: Stress Urinary Incontinence
Interventions: BIOLOGICAL: Autologous adipose-derived mesenchymal stem cells|OTHER: Standard treatment according to the Clinical protocols
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dynamic Change and Immune Response to Nasopharyngeal Carriage and Acute Otitis Media Pathogens
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Otitis Media
Interventions: PROCEDURE: Tympanocentesis|OTHER: Nasal Phalangeal Swab and Wash|OTHER: Blood Draw
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: SYNERGY: Open Study of Enoxaparin Versus Unfractionated Heparin in Patients With Acute Coronary Syndromes
Status: COMPLETED
Conditions: Unstable Angina|Myocardial Infarction|Myocardial Ischemia
Interventions: DRUG: enoxaparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Postoperative Effects of TAP Block Versus QLB Type 2 Block
Status: COMPLETED
Conditions: Inguinal Hernia|Postoperative Pain
Interventions: DRUG: Acetaminophen|DRUG: 0.25% Bupivacaine|DRUG: 0.5% Bupivacaine+Glucose|DRUG: Tramadol HCl|PROCEDURE: Inguinal Hernia Repair|DRUG: 0.25% Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Disulfiram for Cocaine Abuse in Buprenorphine Treatment
Status: COMPLETED
Conditions: Cocaine Dependence|Opioid Dependency
Interventions: DRUG: Disulfiram|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Linaclotide in Treating Patients With Stages 0-3 Colorectal Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Colorectal Adenoma|Stage 0 Colorectal Cancer AJCC v8|Stage I Colorectal Cancer AJCC v8|Stage II Colorectal Cancer AJCC v8|Stage IIA Colorectal Cancer AJCC v8|Stage IIB Colorectal Cancer AJCC v8|Stage IIC Colorectal Cancer AJCC v8|Stage III Colorectal Cancer AJCC v8|Stage IIIA Colorectal Cancer AJCC v8|Stage IIIB Colorectal Cancer AJCC v8|Stage IIIC Colorectal Cancer AJCC v8
Interventions: DRUG: Linaclotide|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT