pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Pilot Study to Evaluate the Effect of Forsteo (Teriparatide, 1-34-rh-PTH) in Anorexia Nervosa Patients With Low Bone Mineral Density and Increased Bone Fagility (FAN-Trial)
Status: UNKNOWN
Conditions: Low Bone Mass in Anorexia Nervosa Patients
Interventions: DRUG: osteoanabolic therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Increased Inoculum on Oral Rotavirus Vaccine Take and Immunogenicity
Status: COMPLETED
Conditions: Rotavirus Infection|Vaccine Response Impaired|Vaccine Virus Shedding
Interventions: BIOLOGICAL: Rotarix, dose 1|BIOLOGICAL: Rotarix, dose 2|DRUG: Placebo (for Rotarix dose 2)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of E7386 in Combination With Other Anticancer Drug in Participants With Solid Tumor
Status: RECRUITING
Conditions: Neoplasms|Carcinoma, Hepatocellular|Liver Neoplasms|Colorectal Neoplasms|Endometrial Neoplasms
Interventions: DRUG: E7386|DRUG: Lenvatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Does Subspinal Le Fort I Osteotomy Affect the Nasal Airway Volume
Status: COMPLETED
Conditions: Maxillofacial Abnormalities
Interventions: PROCEDURE: Conventional|PROCEDURE: Subspinal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Influence of Age, Sepsis and SLCO1A2 Polymorphisms on Rocuronium Pharmacokinetics
Status: COMPLETED
Conditions: Sepsis|Systemic Inflammatory Response Syndrome|Septic Shock
Interventions: PROCEDURE: Serial blood sampling|PROCEDURE: Train of four monitoring|PROCEDURE: Blood testing for liver and renal function|DRUG: General anesthesia|PROCEDURE: Small to medium sized surgery under general anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Fos Biomedical Device on Diabetes Risk Factors and Sleep Quality in Adults at Risk for Type 2 Diabetes
Status: COMPLETED
Conditions: Pre Diabetes
Interventions: DEVICE: Fos Biomedical patch product|DEVICE: Fos Biomedical patch product:placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: French Language Validation of the 5-minutes Montreal Cognitive Assessment (MoCA)
Status: COMPLETED
Conditions: Cognitive Symptom|Evaluations, Diagnostic Self
Interventions: DIAGNOSTIC_TEST: Full version of the Montreal Cognitive Assessment|DIAGNOSTIC_TEST: 5 minutes version of the Montreal Cognitive Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Clinical Evaluation of Venus Versa Octipolar Applicator for Reduction of Abdomen Circumference
Status: TERMINATED
Conditions: Lipodystrophy
Interventions: DEVICE: Venus Versa|OTHER: Glycerine gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Alternative Radiation Fractionation Strategy for Locally Advanced Non-Small Cell Lung Cancer (NSCLC)
Status: UNKNOWN
Conditions: Stage IIA Non-small Cell Lung Cancer|Stage IIB Non-small Cell Lung Cancer|Stage IIIA Non-small Cell Lung Cancer|Stage IIIB Non-small Cell Lung Cancer
Interventions: RADIATION: stereotactic body radiation therapy|DRUG: carboplatin|DRUG: paclitaxel|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral Bioavailability and Bioactivity of Prenylflavonoids From Hops
Status: COMPLETED
Conditions: Safety After Oral Intake|Pharmacokinetics After Oral Intake|Immune Cells Activity
Interventions: DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: 6-prenylnaringenin|DIETARY_SUPPLEMENT: 8-prenylnaringenin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Percutaneous Coronary Intervention (PCI) With Drug-Eluting Stents (DES) Versus Coronary Artery Bypass Graft (CABG) for Patients With Significant Left Main Stenosis
Status: UNKNOWN
Conditions: Coronary Stenosis|Coronary Artery Disease
Interventions: PROCEDURE: Percutaneous coronary intervention (left main)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Effects of a 12-Week Consumption of Two Carbonated Beverages on Insulin Sensitivity
Status: COMPLETED
Conditions: Glucose Homeostasis
Interventions: DIETARY_SUPPLEMENT: Drink with sweeteners|DIETARY_SUPPLEMENT: Drink without sweeteners
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: VIH-1 Colo-rectal Transmission by Infected Semen Cells and Effects of Seminal Plasma ex Vivo (CellspermVIH)
Status: COMPLETED
Conditions: HIV-1-infection
Interventions: OTHER: blood sample|OTHER: sperm sample
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Treatment of Severe Secondary TRIcuspid Regurgitation in Patients With Advance Heart Failure With CAval Vein Implantation of the Edwards Sapien XT VALve (TRICAVAL)
Status: TERMINATED
Conditions: Severe Tricuspid Regurgitation
Interventions: DEVICE: Edwards Sapien XT Valve
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Online Nutrition Education to Decrease the Side Effects of Chemotherapy in Patients With Breast Cancer
Status: NOT_YET_RECRUITING
Conditions: Anatomic Stage I Breast Cancer AJCC v8|Anatomic Stage II Breast Cancer AJCC v8|Anatomic Stage III Breast Cancer AJCC v8
Interventions: OTHER: Best Practice|BEHAVIORAL: Internet-Based Intervention|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Delayed Cord Clamping With Oxygen In Extremely Low Gestation Infants
Status: RECRUITING
Conditions: IVH- Intraventricular Hemorrhage|Extreme Prematurity|Hypoxia Neonatal|Hyperoxia|Respiratory Insufficiency
Interventions: PROCEDURE: Delayed Cord Clamping with Low Oxygen concentration|PROCEDURE: Delayed Cord Clamping with High Oxygen concentration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Fosbretabulin With Everolimus in Neuroendocrine Tumors With Progression
Status: TERMINATED
Conditions: Neuroendocrine Tumors|Everolimus
Interventions: DRUG: everolimus|DRUG: fosbretabulin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Dose Ranging Study of Modafinil for Methamphetamine Dependence
Status: UNKNOWN
Conditions: Substance Dependence|Amphetamine Dependence
Interventions: DRUG: modafinil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Multicentre Pilot Study of Midline Catheter's Tip at a Different Position in Antimicrobial Therapy
Status: COMPLETED
Conditions: Infection
Interventions: DEVICE: Shu Bei Kang (China) Midline Catheters
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Effects of Food on the Pharmacokinetics of DWJ1458 in Healthy Adults
Status: WITHDRAWN
Conditions: Healthy
Interventions: DRUG: DWJ1458 (fasted)|DRUG: DWJ1458 (fed)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study To Evaluate The Effects Of PF-05175157 In Healthy Volunteers
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: PF-05175157|DRUG: PF-05175157|DRUG: PF-05175157|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Feasibility of a Cytokine Expression Profile in Immune Cells as an Orientation Tool in Therapeutic Decisions for Auto-inflammatory and Auto-immune Diseases
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: PROCEDURE: Blood sample
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Comparing Individualized vs. Weight Based Protocols to Treat Vaso-Occlusive Episodes in Sickle Cell Disease
Status: TERMINATED
Conditions: Sickle Cell Disease
Interventions: OTHER: Patient-Specific Protocol|OTHER: Weight-based Protocol|DRUG: Morphine|DRUG: Hydromorphone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Single Treatment of DaxibotulinumtoxinA for Injection in Adults With Isolated Cervical Dystonia (ASPEN-1)
Status: COMPLETED
Conditions: Cervical Dystonia
Interventions: BIOLOGICAL: DaxibotulinumtoxinA for injection|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Technological Based Rehabilitation Practices After Breast Cancer Surgery
Status: NOT_YET_RECRUITING
Conditions: Breast Cancer
Interventions: OTHER: Standard Physiotherapy Exercise Group|OTHER: Telerehabilitation Based Supervised Exercise Group|OTHER: Mobile Application Supported Exercise Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Oral Nitrite Trial for Hypertension and Metabolic Syndrome
Status: WITHDRAWN
Conditions: Metabolic Syndrome|Hypertension
Interventions: DRUG: 14 Nitrogen (N) Sodium Nitrite|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Trastuzumab Emtansine in Comparison With Treatment of Physician's Choice in Participants With HER2-positive Breast Cancer Who Have Received at Least Two Prior Regimens of HER2-directed Therapy
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Trastuzumab emtansine|DRUG: Treatment of physician's choice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Group Music Therapy Interventions on Alzheimer's Disease Patients: a Three-arm Randomized Controlled Blind Study.
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: OTHER: Actice music therapy|OTHER: Watching nature videos|OTHER: Passive music therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of LY3025876 in Participants With Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: LY3025876|DRUG: Placebo|DRUG: Liraglutide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Community-based Provision of Urine Pregnancy Tests as Linkage to Reproductive Health Services
Status: COMPLETED
Conditions: Prenatal Care Late|Contraceptive Usage|Pregnancy Complication
Interventions: DIAGNOSTIC_TEST: Urine Pregnancy Test|BEHAVIORAL: CHV-based post-test counseling & referral|BEHAVIORAL: Phone-based post-test counseling & referral
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Intravenous Aviptadil for Critical COVID-19 With Respiratory Failure
Status: COMPLETED
Conditions: Critical COVID-19 With Respiratory Failure|Acute Respiratory Distress Syndrome (ARDS)|Corona Virus Infection|Acute Lung Injury
Interventions: DRUG: Aviptadil by intravenous infusion + standard of care|DRUG: Normal Saline Infusion + standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Loads, Injuries and Illnesses Among Elite Handball Players
Status: COMPLETED
Conditions: Injuries|Illnesses Systemic|Illness, Chronic|Illnesses, Occupational|Psychological|Physical Illness|Physical Stress|Physical Injury|Physical Trauma|Social Stress|Athletic Injuries
Interventions: OTHER: There is no intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Application of Detecting Circulating Tumor Cells in the Accurate Treatment of Early Stage Lung Adenocarcinoma
Status: UNKNOWN
Conditions: Lung Adenocarcinoma, Stage I|Diagnoses Diseases|Circulating Tumor Cells|Treatment
Interventions: PROCEDURE: lobectomy|PROCEDURE: segmentecomy|DRUG: chemotherapy（pemetrexed+CISPLATIN）|PROCEDURE: Lymphadenectomy|OTHER: CanPatrolTM to detect CTCs
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mitoxantrone Hydrochloride Liposome Injection-containing Bridging Regimen and CD19-targeting CAR-T Therapies
Status: RECRUITING
Conditions: B-cell Acute Lymphoblastic Leukemia|B-cell Lymphoma Refractory
Interventions: DRUG: Mitoxantrone hydrochloride liposome Injection-based bridging therapy+ Fludarabine-based chemotherapy +CD19 CAR-T Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigation of Pharmacokinetics of BIBX 245 CL and Safety in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BIBX 245 CL - fed|DRUG: BIBX 245 CL- fasted
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: C7R-GD2.CAR T Cells for Patients With GD2-expressing Brain Tumors (GAIL-B)
Status: RECRUITING
Conditions: Diffuse Intrinsic Pontine Glioma|High Grade Glioma|Embryonal Tumor|Ependymal Tumor
Interventions: GENETIC: C7R-GD2.CART cells (ICV infusion)|GENETIC: C7R-GD2.CART cells (IV infusion)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of CB1 Antagonist ANEB-001 in a THC Challenge Test
Status: COMPLETED
Conditions: Acute Cannabinoid Intoxication
Interventions: DRUG: ANEB-001|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efects of Noninvasive Mechanical Ventilation and Conventional Mechanical Ventilation in Patients With Severe Comunity Pneumonia
Status: TERMINATED
Conditions: Community Acquired Pneumonia.|Acute Hypoxemic Respiratory Failure
Interventions: DEVICE: Non invasive mechanical ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: SOURCE XT REGISTRY
Status: COMPLETED
Conditions: Severe Aortic Stenosis
Interventions: DEVICE: TAVR Implantation of the Transcatheter Aortic Valve Prosthesis|DEVICE: TAVR Implantation of the Transcatheter Aortic Valve Prosthesis|DEVICE: TAVR Implantation of the Transcatheter Aortic Valve Prosthesis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: NLA101 in Adults Receiving High Dose Chemotherapy for AML
Status: TERMINATED
Conditions: Leukemia, Myeloid, Acute
Interventions: BIOLOGICAL: NLA101|DRUG: Standard of Care (SOC) chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: ALK21-006: Long-Term Study of Medisorb® Naltrexone (VIVITROL®)
Status: COMPLETED
Conditions: Alcoholism
Interventions: DRUG: Medisorb naltrexone 380 mg|DRUG: Oral naltrexone 50 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Nebulized Lidocaine on the Quality of Laryngeal Mask Airway Insertion
Status: UNKNOWN
Conditions: Airway Complication of Anesthesia
Interventions: DRUG: Lidocaine Hydrochloride|DRUG: Distilled Water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Investigation of Acceptable Dose of Mobilisation and Tactile Stimulation to Enhance Upper Limb Recovery After Stroke
Status: COMPLETED
Conditions: Stroke
Interventions: BEHAVIORAL: Conventional UK physical therapy|PROCEDURE: Con UK PT + Mobilisation & tactile stimulation (MTS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Donepezil HCl & Cognitive Deficits in Autism
Status: COMPLETED
Conditions: Autistic Disorder
Interventions: DRUG: Donepezil HCl|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Language & Cognitive Control
Status: COMPLETED
Conditions: Language|Methylphenidate of Undetermined Intent
Interventions: DRUG: Methylphenidate 20 Mg Oral Tablet|DRUG: Placebo|BEHAVIORAL: Language Task|BEHAVIORAL: Rest Recording|BEHAVIORAL: Go/No-Go Task|BEHAVIORAL: Processing Speed|BEHAVIORAL: Operation Span|BEHAVIORAL: Reading Span|BEHAVIORAL: Barratt Impulsiveness Scale
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Ceftidoren Versus Levofloxacin in the Treatment of Patients With Acute Exacerbations of Chronic Bronchitis (AECB)
Status: COMPLETED
Conditions: COPD Exacerbation
Interventions: DRUG: ceftidoren|DRUG: levofloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pramipexole (BI-Sifrol®) Orally Once Daily for 6 Weeks in Patients With Primary Restless Legs Syndrome
Status: COMPLETED
Conditions: Restless Legs Syndrome
Interventions: DRUG: Pramipexole 0.125 mg tablets|DRUG: Pramipexole 0.125 mg tablets Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Docetaxel, Oxaliplatin, Capecitabine, Bevacizumab and Trastuzumab in Patients With Locally Advanced or Metastatic Gastric Cancer
Status: UNKNOWN
Conditions: Metastatic Gastric Cancer|Adenocarcinoma of the Gastro-oesophageal Junction
Interventions: DRUG: Docetaxel, Oxaliplatin, Capecitabin, Bevacizumab|DRUG: Docetaxel, Oxaliplatin, Capecitabin, Bevacizumab, Trastuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose:
Clinical trial: Efficacy and Safety of Semaglutide Once-weekly Versus Placebo in Drug-naïve Subjects With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: semaglutide|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Nasal Continuous Positive Airway Pressure Versus Standard Care During Procedural Sedation for Gastrointestinal Endoscopy
Status: COMPLETED
Conditions: Hypoxia|Endoscopy|Anesthesia Morbidity
Interventions: DEVICE: Nasal Mask|DEVICE: Control: Nasal Cannula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Abnormal Movements, Cerebellum and Sensorimotor : Oculomotor Study
Status: COMPLETED
Conditions: Healthy|Dystonia|Parkinson Disease
Interventions: DEVICE: Tracking eye movement|DEVICE: Tracking eye movement under deep brain stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Psychological Intervention Using Smartphone Technology to Alleviate Malignant Pain
Status: RECRUITING
Conditions: Cancer Pain|Opioid Use|Cognitive Behavior Therapy
Interventions: BEHAVIORAL: Cognitive Behavioral Therapy for pain
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: To Assess Safety, Tolerability, Pharmacokinetics/Pharmacodynamics and the Effect of Fasting After Single Oral Doses of AZD5658 in Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: AZD5658|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: In Vivo Endomicroscopic Description of Pulmonary Microcirculation in Systemic Sclerosis and Emphysema Patients
Status: UNKNOWN
Conditions: Pulmonary Disease|Pulmonary Emphysema
Interventions: DEVICE: Bronchoscopy with in vivo confocal endomicroscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Trial Evaluating Hypnosis Using Virtural Reality vs Standard Pain Management During Musculoskelettal Biopsy
Status: COMPLETED
Conditions: Musculoskeletal Cancers
Interventions: PROCEDURE: Deep local anesthesia + Virtual reality|PROCEDURE: Deep local anesthesia alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of the Treatment of Plantar Orthoses With Extracorporeal Shock Wave Therapy in Plantar Fasciitis
Status: COMPLETED
Conditions: Fasciitis, Plantar, Chronic
Interventions: DEVICE: customised foot orthoses|DEVICE: orthotic insole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Intrauterine Injection of Human Chorionic Gonadotropin Before Embryo Transfer in Women With Previous IVF Failure
Status: UNKNOWN
Conditions: Infertility|Invitro Fertilization
Interventions: DRUG: Human Chorionic Gonadotropin (HCG)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Microwave Ablation for Treatment of Small Renal Tumors and Primary and Secondary Liver Neoplasms
Status: RECRUITING
Conditions: Liver Cancer|Liver Metastasis Colon Cancer|Kidney Cancer|Renal Cell Carcinoma
Interventions: PROCEDURE: Microwave ablation (MWA)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Ixazomib and Rituximab in Treating Patients With Relapsed or Refractory Mantle Cell Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Recurrent Mantle Cell Lymphoma|Refractory Mantle Cell Lymphoma
Interventions: DRUG: Ixazomib|DRUG: Ixazomib Citrate|BIOLOGICAL: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acceptability of Products and Eating Pleasure in Elderly People Living at Home or in Establishment Hosting For the Dependant Elderly (EHPAD) (Old-people's Home)
Status: UNKNOWN
Conditions: Nutrition
Interventions: DIETARY_SUPPLEMENT: Session A: Experimental products (selected enriched products)|DIETARY_SUPPLEMENT: Experimental session: to select enriched products|DIETARY_SUPPLEMENT: Session B: Control (standard products without enrichment)|DIETARY_SUPPLEMENT: Control session
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Fractional Carbon Dioxide Laser Versus UVA 1 in Treatment of Localized Scleroderma
Status: UNKNOWN
Conditions: Localized Scleroderma
Interventions: DEVICE: Fractional carbon dioxide laser|DEVICE: Ultraviolet A1 phototherapy (UVA1)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess Efficacy and Safety of Aclidinium Bromide and Aclidinium Bromide/Formoterol Fumarate in Stabile COPD Patients
Status: COMPLETED
Conditions: COPD
Interventions: DRUG: Aclidinium bromide/formoterol Fixed-Dose Combination|DRUG: Aclidinium bromide|DRUG: Formoterol Fumarate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Multi-Component Weight Loss Intervention to Improve Outcomes of Total Knee Replacement
Status: RECRUITING
Conditions: Arthropathy of Knee|Obesity
Interventions: BEHAVIORAL: Multi-Component Weight Loss Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Evaluation of PCV13 Vaccine Schedules, Comparing Impact of 2+1 vs 3+0 on Pneumococcal Carriage in Blantyre, Malawi
Status: RECRUITING
Conditions: 13-valent Pneumococcal Vaccine|Streptococcus Pneumoniae
Interventions: OTHER: nasopharyngeal swab
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: PET Imaging of Inflammation and Lipid Lowering Study
Status: RECRUITING
Conditions: Hypercholesterolemia|Hypercholesterolemia, Familial|Atherosclerosis|Carotid Artery Plaque
Interventions: DRUG: Inclisiran|DIAGNOSTIC_TEST: 68Ga-DOTATATE PET-MRI|DRUG: Colchicine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: INSIGHT-AHP: A Study to Characterize the Prevalence of Acute Hepatic Porphyria (AHP) in Patients With Clinical Presentation and History Consistent With AHP
Status: TERMINATED
Conditions: Acute Hepatic Porphyria|Hepatic Porphyrias|Acute Intermittent Porphyria (AIP)|Hereditary Coproporphyria (HCP)|Variegate Porphyria (VP)|ALA Dehydratase Deficient Porphyria (ADP)|Porphyria Acute
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Silicone Hydrogel Contact Lens Clinical and Comfort Benefits With a Multi-Purpose Disinfecting Solution
Status: COMPLETED
Conditions: Refractive Error|Myopia|Hyperopia|Astigmatism|Presbyopia
Interventions: DEVICE: Lotrafilcon B contact lenses|DEVICE: Senofilcon A contact lenses|DEVICE: OPTI-FREE PureMoist Multi-Purpose Disinfecting Solution (MPDS)|DEVICE: Habitual Multi-Purpose Solution (MPS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phase 2 Dose-Response Study Evaluating the Safety and Efficacy of NCX 470 vs Latanoprost in Subjects With Open-Angle Glaucoma or Ocular Hypertension
Status: COMPLETED
Conditions: Glaucoma, Open-Angle|Hypertension, Ocular
Interventions: DRUG: NCX 470|DRUG: Latanoprost 0.005%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Regional Hypothermia in Combination With Endovascular Thrombectomy in Acute Ischemic Stroke
Status: UNKNOWN
Conditions: Stroke|Neuroprotection|Hypothermia
Interventions: OTHER: Regional Hypothermia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Patients Undergoing Laparoscopic Nephrectomy Walk Out From Operating Room After Surgery
Status: RECRUITING
Conditions: Laparoscopic Nephrectomy|Enhanced Recovery After Surgery
Interventions: BEHAVIORAL: walk out from operating room
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of PT on QL, FC, PWV and Biochemical Markers in CRF on Conservative Treatment
Status: UNKNOWN
Conditions: Kidney Failure, Chronic|Resistance Training|Treatment
Interventions: BEHAVIORAL: Physical training|BEHAVIORAL: Stretching and metabolic exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy and Safety of Prochymal® Infusion in Combination With Corticosteroids for the Treatment of Newly Diagnosed Acute Graft Versus Host Disease (GVHD)
Status: COMPLETED
Conditions: Graft Versus Host Disease
Interventions: DRUG: Prochymal®|OTHER: Placebo|OTHER: Corticosteroid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study With [18F]MNI-1054 to Determine Lysine -Specific Demethylase 1A (LSD1) Brain Enzyme Occupancy of TAK-418 After Single-Dose Oral Administration in Healthy Participants
Status: TERMINATED
Conditions: Healthy Volunteers
Interventions: DRUG: TAK-418|DRUG: [18F]MNI-1054 (radiotracer)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Prevalence of Epilepsy and Sleep Wake Disorders in Alzheimer Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Alzheimer Disease|Alzheimer Dementia|Epilepsy|Sleep Wake Disorders
Interventions: DIAGNOSTIC_TEST: scalp EEG and polysomnography|DIAGNOSTIC_TEST: scalp EEG with foramen ovale electrodes with polysomnography
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Multi-Center Study of Riociguat in Patients With Sickle Cell Diseases
Status: COMPLETED
Conditions: Sickle Cell Disease
Interventions: DRUG: Riociguat|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Loxoprofen Hydrogel Patch in Patients With Ankylosing Spondylitis
Status: COMPLETED
Conditions: Ankylosing Spondylitis
Interventions: DRUG: Loxoprofen sodium hydrogel patch|DRUG: Loxoprofen sodium tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exploratory Clinical Trial to Safety and Efficacy of SAT-003 in Cancer Cachexia Patients Discontinued Chemotherapy Who Had Diagnosed With Solid Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Cancer Cachexia
Interventions: DEVICE: SAT-003
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Sexual Counseling Based on PLISSIT Model to Women Undergoing Open Heart Surgery on Sexual Function and Sexual Quality of Life
Status: UNKNOWN
Conditions: PLISSIT Model|Sexual Counselling
Interventions: OTHER: sexual counselling with plissit model
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Assessment and Telerehabilitation of Cognitive and Motor Skills in Children With Neurodevelopmental Disabilities (Tablet Project)
Status: RECRUITING
Conditions: Neurodevelopmental Cognitive, Motor and Speech-language Disabilities
Interventions: DEVICE: Telerehabilitation VRRS
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Deep vs Moderate Neuromuscular Blocks on Remifentanil for Laparoscopic Gastrectomy
Status: COMPLETED
Conditions: Gastric Cancer
Interventions: DRUG: Neostigmine + glycopyrate|DRUG: Sugammadex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: To Evaluate HU-045 in the Treatment of Glabellar Lines(Phase III)
Status: NOT_YET_RECRUITING
Conditions: Glabellar Lines
Interventions: DRUG: HU-045|DRUG: Xeomin®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Lymphodepletion and Anti-PD-1 Blockade to Reduce Relapse in AML Patient Not Eligible for Transplant
Status: COMPLETED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Fludarabine|DRUG: Melphalan|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessing the Efficacy of Passive Exoskeletons for Construction Work: Lab-Based Study
Status: UNKNOWN
Conditions: Healthy
Interventions: DEVICE: Laevo 2|DEVICE: backX|DEVICE: FLx ErgoSkeleton|DEVICE: V22 ErgoSkeleton
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Fractional Laser Assisted Steroid Therapy vs Intralesional Steroids in the Treatment of Keloids
Status: COMPLETED
Conditions: Keloid
Interventions: DEVICE: The Lutronic electronic carbon dioxide (eCO2) Plus laser system|DRUG: Intralesional Triamcinolone Acetonide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Autologous Bone Marrow Stem Cells in Ischemic Stroke.
Status: COMPLETED
Conditions: Stroke, Acute|Infarction, Middle Cerebral Artery
Interventions: BIOLOGICAL: Infusion of autologous CD34+ stem cells into middle cerebral artery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effectiveness of a Micronutrient Supplement to Lower Plasma Homocysteine MDEG2 Pilot Supplementation Trial
Status: COMPLETED
Conditions: Micronutrient Deficiencies|Hyperhomocysteinemia
Interventions: DIETARY_SUPPLEMENT: novel micronutrient|DIETARY_SUPPLEMENT: existing micronutrient supplement, UNIMMAP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SJG-136 in Treating Patients With Epithelial Ovarian, Primary Peritoneal, or Fallopian Tube Cancer That Did Not Respond to Previous Treatment With Cisplatin or Carboplatin
Status: TERMINATED
Conditions: Recurrent Fallopian Tube Cancer|Recurrent Ovarian Epithelial Cancer|Recurrent Primary Peritoneal Cavity Cancer
Interventions: DRUG: SJG-136|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study on Radiogenomics Features Associated With Radiochemotherapy Sensitivity in Gliomas
Status: RECRUITING
Conditions: Glioma
Interventions: DIAGNOSTIC_TEST: Assess the response glioma to radiochemotherapy using radiogenomics-based AI model
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Dapagliflozin Effect on Cardiovascular Outcomes in Haemodialysis for End Stage Renal Disease
Status: WITHDRAWN
Conditions: Cardiovascular Diseases|End Stage Renal Disease
Interventions: DRUG: Dapagliflozin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Functional Neuroimaging in Fibromyalgia Patients Receiving tDCS
Status: UNKNOWN
Conditions: Fibromyalgia|Chronic Pain
Interventions: DRUG: Pregabalin|OTHER: Transcranial Direct Current Stimulation|OTHER: Sham Transcranial Direct Current Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Clinical Phase I Study Investigating MSC2490484A, an Inhibitor of a DNA-dependent Protein Kinase, in Advanced Solid Tumors or Chronic Lymphocytic Leukemia
Status: COMPLETED
Conditions: Advanced Solid Tumors|Chronic Lymphocytic Leukemia
Interventions: DRUG: MSC2490484A (M3814)
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Branched Thoracic Endovascular Grafts for the Treatment of Thoraco-abdominal Aortic
Status: RECRUITING
Conditions: Thoracoabdominal Aortic Aneurysm, Without Rupture
Interventions: DEVICE: B-TEVAR device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Real-world Clinical Effectiveness of Whole Genome and Transcriptome Analysis to Guide Advanced Cancer Care
Status: UNKNOWN
Conditions: Metastatic Cancer|Advanced Cancer|Cancers That Cannot be Treated With Curative Intent
Interventions: GENETIC: Initiation of POG-related WGTA|GENETIC: Usual care
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: VR-treadmill Combined Intervention for Enhancing Mobility and Cognitive Function in Patients With Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: BEHAVIORAL: Treadmill training with Virtual Reality|BEHAVIORAL: Treadmill training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Developing Memory Reconsolidation Blockers as Novel Posttraumatic Stress Disorder (PTSD) Treatments
Status: COMPLETED
Conditions: Post-traumatic Stress Disorder
Interventions: DRUG: Mifepristone|DRUG: d-Cycloserine|DRUG: Placebo-matching Mifepristone|DRUG: Placebo-matching d-Cycloserine (DCS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Diagnostic Procedures in Women With Locally Advanced Breast Cancer Who Are Receiving Chemotherapy Before Breast Cancer Surgery
Status: COMPLETED
Conditions: Breast Cancer
Interventions: PROCEDURE: biopsy|PROCEDURE: magnetic resonance imaging|PROCEDURE: radiomammography|PROCEDURE: ultrasound imaging|RADIATION: gadopentetate dimeglumine|DRUG: chemotherapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pradaxa Study in Non-valvular Atrial Fibrillation Patients With Severely Impaired Renal Function
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DRUG: Pradaxa, dabigatran etexilate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Adjuvant Dexamethasone on Postoperative Pain, Analgesic Consumption and Block Properties in SFIB
Status: COMPLETED
Conditions: Regional Anesthesia
Interventions: PROCEDURE: Suprainguinal fascia iliaca block|PROCEDURE: Suprainguinal fascia iliaca block+dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Subconjunctival Injection of Local Anesthetic in Anterior Blepharoptosis Repair
Status: UNKNOWN
Conditions: Blepharoptosis|Ptosis
Interventions: DRUG: Subcut. + Subconj. Xylocaine|DRUG: Subcut. + Sham Subconj. Injection|PROCEDURE: Blepharoptosis Repair
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: 17-N-Allylamino-17-Demethoxygeldanamycin in Treating Patients With Metastatic Malignant Melanoma
Status: COMPLETED
Conditions: Melanoma (Skin)
Interventions: DRUG: tanespimycin
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Garcinia Mangostana L.Pericarp Gel as a Local Drug Delivery in Treatment of Chronic Periodontitis
Status: COMPLETED
Conditions: Generalized Chronic Periodontitis
Interventions: DRUG: Garcinia mangostana|DRUG: Placebo gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Little Cigar and Cigarillo Warnings for Youth
Status: RECRUITING
Conditions: Little Cigars and Cigarillos (LCC) Use
Interventions: BEHAVIORAL: FDA warnings + Image|BEHAVIORAL: FDA Warnings Text-Only|BEHAVIORAL: Surgeon General Text-Only Warnings
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Operative or Conservative Treatment of Acute Acromioclavicular Joint Dislocation
Status: COMPLETED
Conditions: Acromioclavicular Joint Dislocation
Interventions: PROCEDURE: hook plate|OTHER: Physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Prospective Observational Study to Describe Clinical Outcomes, Treatment Patterns, Patients Characteristics Among Patients With HR+/HER2- Advanced BC Initiating Treatment With Risarg®, Piqray®, Endocrine Therapy or Chemotherapy in Routine Clinical Practice in Russia
Status: RECRUITING
Conditions: Breast Cancer
Interventions: OTHER: ribociclib|OTHER: aplelicib|OTHER: mono endocrine therapy|OTHER: chemotherapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of Belzutifan (MK-6482) in Combination With Palbociclib Versus Belzutifan Monotherapy in Participants With Advanced Renal Cell Carcinoma (MK-6482-024/LITESPARK-024)
Status: RECRUITING
Conditions: Renal Cell Carcinoma
Interventions: DRUG: Belzutifan|DRUG: Palbociclib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Square-stepping Exercise on Frailty and Cognitive Function in Elderly With Frailty and MCI
Status: UNKNOWN
Conditions: Frailty|Mild Cognitive Impairment
Interventions: OTHER: Square-stepping exercise|OTHER: Stretching and strengthening
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dental Implant Supported Removable Dental Prostheses
Status: COMPLETED
Conditions: Implant Complication|Prosthesis Survival
Interventions: PROCEDURE: placement of implants|PROCEDURE: immediate loading|PROCEDURE: conventional loading|DEVICE: Ankylos implant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant/Adjuvant Sintilimab, Nab-paclitaxel, and Gemcitabine for Resectable/Borderline Resectable Pancreatic Cancer
Status: NOT_YET_RECRUITING
Conditions: Pancreatic Cancer, Stage IB|Pancreatic Cancer, Stage IIA|Pancreatic Cancer, Stage IIB|Pancreatic Cancer Stage III
Interventions: DRUG: sintilimab|DRUG: nab-paclitaxel|DRUG: gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multiple Dose Study In Cancer Patients: Safety and Tolerability of BMS-754807 in Combination With Paclitaxel and Carboplatin in Patients With Advanced or Metastatic Solid Tumors
Status: COMPLETED
Conditions: Advanced Solid Tumors|Metastatic Solid Tumors
Interventions: DRUG: BMS-754807|DRUG: Paclitaxel|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diagnostic Biomarkers to Correlate Molecular Changes and Inflammatory Cascade in the Dental Pulp.
Status: COMPLETED
Conditions: Vital Pulp Therapy
Interventions: PROCEDURE: Pulp therapy|DIAGNOSTIC_TEST: Cytokines level in pulpal blood.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Efficacy and Safety of Ibuprofen 50 mg/g Gel Compared to Profenid 25mg/g Gel
Status: UNKNOWN
Conditions: Muscular Atrophy|Sprains|Tendonitis
Interventions: DRUG: Ibuprofen|DRUG: Profenid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 17-N-Allylamino-17-Demethoxygeldanamycin in Treating Patients With Chronic Phase Chronic Myelogenous Leukemia That Did Not Respond to Imatinib Mesylate
Status: COMPLETED
Conditions: Leukemia
Interventions: DRUG: tanespimycin
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HLA-G Immuno-Inhibitor Checkpoint Study in Patients With COVID-19 Infection: Molecular and Cellular Assessment
Status: COMPLETED
Conditions: Covid19
Interventions: OTHER: Baseline and during hospitalization blood samples|OTHER: Baseline blood sample
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Impact of the Relaxation Response Resiliency Program on Patients With Atrial Fibrillation
Status: COMPLETED
Conditions: Atrial Fibrillation|Stress|Quality of Life|Anxiety|Depression|Hostility
Interventions: BEHAVIORAL: Relaxation Response Resiliency Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE