pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Virtual 1-Session Spanish "Empowered Relief" Group Intervention for Chronic Pain
Status: RECRUITING
Conditions: Chronic Pain
Interventions: OTHER: Usual Care|BEHAVIORAL: Empowered Relief
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Platelet-Directed Whole Blood Transfusion Strategy for Malaria
Status: RECRUITING
Conditions: Severe Malaria|Thrombocytopenia
Interventions: OTHER: Whole blood transfusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of Integrating MIYCN Interventions in Existing CGPP of PCI
Status: COMPLETED
Conditions: Polio
Interventions: OTHER: Maternal dietary diversity|OTHER: Diet diversity in complementary feeding|OTHER: Exclusive Breast Feeding|OTHER: Community mobilization|OTHER: Capacity Building|OTHER: Use of existing platforms VHSND|OTHER: Strategic use of data
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Comparison of SITA-Standard Compared to SITA-Fast Visual Fields.
Status: UNKNOWN
Conditions: Glaucoma
Interventions: DIAGNOSTIC_TEST: SITA FAST VISUAL FIELD TEST|DIAGNOSTIC_TEST: SITA STANDARD VISUAL FIELD TEST
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Postoperative Controls of Ventilation Tubes in Children - by General Practitioner or Otolaryngologist?
Status: COMPLETED
Conditions: Otitis
Interventions: PROCEDURE: general practice follow-up|PROCEDURE: ear-nose-throat (ENT) specialist follow-up
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Endoscopic Sleeve Gastroplasty for Morbid Obesity
Status: UNKNOWN
Conditions: Endoscopic Sleeve Gastroplasty
Interventions: PROCEDURE: Endoscopic Sleeve Gastroplasty|PROCEDURE: Laparoscopic Sleeve Gastrectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Photocil (Topical) for the Treatment of Vitiligo
Status: COMPLETED
Conditions: Vitiligo
Interventions: DRUG: Photocil for Vitiligo|OTHER: Placebo - Sunscreen (SPF 2)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ESSENTIAL-"The Studies of Oral Enoximone Therapy in Advanced Heart Failure"
Status: TERMINATED
Conditions: Heart Failure, Congestive
Interventions: DRUG: Enoximone|DRUG: Enoximone placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Microbial Load After Apical Enlargement in Asymptomatic Teeth With Periapical Lesion
Status: NOT_YET_RECRUITING
Conditions: Root Canal Infection|Periapical Diseases|Periapical; Infection|Endodontic Disease
Interventions: PROCEDURE: apical shaping size
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effectiveness of Salvadora Persica Miswak in Improving Plaque Control and Gingival Health
Status: UNKNOWN
Conditions: Gingivitis|Dental Plaque
Interventions: DEVICE: The novel Salvadora persica toothbrush|DEVICE: The Salvadora persica (miswak) chewing stick|DEVICE: Standard toothbrush and toothpaste (control)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: N=1 Trials of Individual Variability in Post-prandial Glycemic Responses to Diets of Varying Macronutrient Composition
Status: ACTIVE_NOT_RECRUITING
Conditions: Personalized Nutrition
Interventions: DIETARY_SUPPLEMENT: High Protein Diet|DIETARY_SUPPLEMENT: High Fat Diet|DIETARY_SUPPLEMENT: High Carbohydrate-Low Glycemic Index Diet|DIETARY_SUPPLEMENT: High Carbohydrate-High Glycemic Index Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Does Low-Dose Aspirin Improve Outcome in In Vitro Fertilisation/Intra Cytoplasmatic Sperm Injection (IVF/ICSI)?
Status: COMPLETED
Conditions: Infertility
Interventions: DRUG: aspirin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of SR46349B in Patients With Sleep Disorders in Fibromyalgia
Status: COMPLETED
Conditions: Fibromyalgia|Sleep|Chronic Pain
Interventions: DRUG: eplivanserin (SR46349)|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sofosbuvir/Ombitasvir/Paritaprevir/ Ritonavir and Ribavirin for Hepatitis C Virus Genotype 4 Patients
Status: COMPLETED
Conditions: Chronic Hepatitis C Virus Infection
Interventions: DRUG: SOF plus (OBV/PTV/r) plus RBV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diagnostic Utility of Pleural Fluid MAGE Assay in Patients With Pleural Effusion From Primary Lung Cancer
Status: COMPLETED
Conditions: Unilatral Pleural Effusion
Interventions: PROCEDURE: pleural fluid tapping
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Erector Spinae Plane Block With Ropivacaine for Major Upper Abdominal Surgery
Status: UNKNOWN
Conditions: Pain, Postoperative
Interventions: DRUG: Ropivacaine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intravitreal Ranibizumab to Treat Macular Edema After Panretinal Photocoagulation (Phase II)
Status: TERMINATED
Conditions: Proliferative Diabetic Retinopathy|Macular Edema
Interventions: DRUG: ranibizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dynamic 99mTc-Tetrofosmin CZT-SPECT Myocardial Perfusion Imaging in Comparison With Fractional Flow Reserve in Patients After ST-elevation Myocardial Infarction
Status: RECRUITING
Conditions: Myocardial Infarction
Interventions: DIAGNOSTIC_TEST: Dynamic 99mTc-Tetrofosmin CZT-SPECT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of Lamotrigine to Treat Ménière's Disease
Status: COMPLETED
Conditions: Meniere's Disease|Ménière's Vertigo|Vertigo, Intermittent|Vertigo, Aural
Interventions: DRUG: Lamotrigine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Immunogenicity, and Safety Study of a Respiratory Syncytial Virus Vaccine in Infants and Toddlers
Status: RECRUITING
Conditions: RSV Immunisation
Interventions: BIOLOGICAL: RSVt Vaccine|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: An Exploratory Trial Investigating the Neurogenic Component in Psoriasis Vulgaris by Use of Botulinum Toxin A
Status: COMPLETED
Conditions: Psoriasis Vulgaris
Interventions: DRUG: Botulinum Toxin Type A|DRUG: Sodium chloride 9 mg/ml
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: A Self-help Book for Insomnia Compared With Sleep Hygiene Advice in Patients Using Sleep Medications
Status: COMPLETED
Conditions: Hypnotic; Sleep Disorder
Interventions: OTHER: self-help book|OTHER: sleep hygiene advice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of MHAA4549A to Assess Safety And Pharmacokinetics in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: MHAA4549A|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Changes of Soft and Hard Tissues After Alveolar Ridge Preservation: Freeze-dried Bone Allograft vs. L-PRF Clot
Status: COMPLETED
Conditions: Alveolar Bone Loss|Tooth Loss
Interventions: BIOLOGICAL: Freeze Dried Bone Allograft|BIOLOGICAL: L-PRF clot
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: X-ray Evaluation of the Effectiveness of the Atlas Correction in Patients With Chronic Subluxation of the Atlas
Status: COMPLETED
Conditions: Subluxation and Dislocation of C0/C1 Cervical Vertebrae
Interventions: PROCEDURE: Atlas-Standard method
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Induction Intensification in Treating Infants With Newly Diagnosed Acute Lymphoblastic Leukemia
Status: COMPLETED
Conditions: Leukemia
Interventions: BIOLOGICAL: filgrastim|DRUG: asparaginase|DRUG: cyclophosphamide|DRUG: cytarabine|DRUG: daunorubicin hydrochloride|DRUG: etoposide|DRUG: leucovorin calcium|DRUG: mercaptopurine|DRUG: methotrexate|DRUG: prednisone|DRUG: therapeutic hydrocortisone|DRUG: vincristine sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Afatinib Therapy for Potentially Resectable Stage III EGFR Mutation-Positive Lung Adenocarcinoma
Status: COMPLETED
Conditions: Lung Adenocarcinoma Stage III|EGFR Gene Mutation
Interventions: DRUG: Afatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Elizaria® vs. Soliris® in Patients With PNH
Status: COMPLETED
Conditions: Paroxysmal Nocturnal Hemoglobinuria|Marchiafava-Micheli Syndrome|Paroxysmal Hemoglobinuria
Interventions: BIOLOGICAL: Elizaria®|BIOLOGICAL: Soliris®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of BiosLife on Serum Lipids
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DIETARY_SUPPLEMENT: BiosLife Complete|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study With NVDX3 for Treatment of Low Grade Degenerative Lumbar Spondylolisthesis
Status: ACTIVE_NOT_RECRUITING
Conditions: Degenerative Lumbar Spondylolisthesis
Interventions: DRUG: NVDX3
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oxytocin and Eating
Status: UNKNOWN
Conditions: Weight Gain
Interventions: DRUG: Syntocinon|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study in Previously Untreated Chronic Lymphocytic Leukemia (CLL) Subjects, Excluding Those With the 17p Deletion, to Evaluate Debulking Regimens Prior to Initiating Venetoclax Combination Therapy
Status: COMPLETED
Conditions: Chronic Lymphocytic Leukemia (CLL)|Small Lymphocytic Lymphoma (SLL)
Interventions: DRUG: Obinutuzumab|DRUG: Bendamustine|DRUG: Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fotemustine and Dacarbazine Versus Dacarbazine +/- Alpha Interferon in Advanced Malignant Melanoma
Status: COMPLETED
Conditions: Malignant Melanoma|Recurrent Melanoma
Interventions: DRUG: Dacarbazine|DRUG: Fotemustine|DRUG: Interferon Alfa-2b
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Lacosamide in Peripheral Neuropathic Pain
Status: TERMINATED
Conditions: Neuropathic Pain|Neuropathy;Peripheral|Neuropathy, Painful|Neuropathy, Diabetic|Neuropathy
Interventions: DRUG: Lacosamide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Transcutaneous Electrical Nerve Stimulation on People With Muscle Fatigue Due to Training, Sports
Status: UNKNOWN
Conditions: Muscle Fatigue
Interventions: DEVICE: electrical stimulation|DEVICE: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: ACTIONS - Aortic Counterpulsation to Improve Outcomes in Noncardiac Surgery
Status: TERMINATED
Conditions: Patients With History of Ischemic Heart Disease With LV Dysfunction Undergoing Noncardiac Surgery
Interventions: DEVICE: IABP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Combination of SAR3419 and Rituximab in Relapsed/Refractory Diffuse Large B-Cell Lymphoma
Status: COMPLETED
Conditions: Diffuse Large B-Cell Lymphoma
Interventions: DRUG: SAR3419|DRUG: rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combined Simultaneous EGD-colonoscopy Trial (CoSi Endoscopy)
Status: COMPLETED
Conditions: Procedure Time
Interventions: PROCEDURE: Simultaneous EGD and colonoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Clinical Study to Assess the Effects of a Stannous Fluoride Dentifrice on Plaque and Gingivitis
Status: COMPLETED
Conditions: Gingivitis
Interventions: DRUG: Marketed toothpaste|DRUG: Marketed Cavity Protection Toothpaste
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lapatinib In Combination With Chemotherapy In Subjects With Relapsed Breast Cancer
Status: TERMINATED
Conditions: Relapsed Breast Cancer|Neoplasms, Breast
Interventions: DRUG: Lapatinib|DRUG: Capecitabine|DRUG: Docetaxel|DRUG: nab-Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Electroconvulsive Therapy (ECT) in Chronic, Severe, Treatment Resistant Posttraumatic Stress Disorder
Status: COMPLETED
Conditions: Posttraumatic Stress Disorder
Interventions: PROCEDURE: Electroconvulsive Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and PK Study of BIBF 1120 in Japanese Patients With IPF: Follow up Study From 1199.31(NCT01136174)
Status: COMPLETED
Conditions: Pulmonary Fibrosis
Interventions: DRUG: Nintedanib|DRUG: Pirfenidoneone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RItuximab Long-Term DOSE Trial in Multiple Sclerosis - RIDOSE-MS
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Sclerosis, Relapsing-Remitting
Interventions: DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Drug Interaction Study - Assess Pharmacokinetics of Both AZD5672 and Atorvastatin
Status: COMPLETED
Conditions: Healthy Volunteers|Pharmacokinetics
Interventions: DRUG: AZD5672|DRUG: atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Rollover Study for Continued Safety and Tolerability in Subjects Treated With Spartalizumab Alone or in Combination With Other Study Treatments
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Solid Tumors
Interventions: DRUG: PDR001
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Microbial Epidemiology and Chlorhexidine Suscebtibily of Oropharyngeal and Intestinal Colonization
Status: COMPLETED
Conditions: Oropharyngeal Gram-negative Bacilli Colonization
Interventions: OTHER: oropharyngeal swabbing|OTHER: rectal swabbing
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Observational Study Evaluating the Quality of Pegylated Interferon Alfa-2a and Ribavirin Treatment for Chronic Hepatitis C in Cooperation With the BNG (Association of German Resident Gastroenterologists)
Status: COMPLETED
Conditions: Chronic Hepatitis C
Interventions: DRUG: Pegylated interferon alfa-2a|DRUG: Ribavirin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Radiographic Progression of Infiltrated Caries Lesions In-vivo
Status: COMPLETED
Conditions: Dental Caries
Interventions: DEVICE: Resin infiltration|BEHAVIORAL: Caries management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of 300 mg Ibuprofen Prolonged-Release Tablets for the Treatment of Pain After Surgical Removal of Impacted Third Molars
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Ibuprofen 300 mg Oral Tablet|DRUG: Ibuprofen 200 mg Oral Tablet|DRUG: Placebo of PR tablet|DRUG: Placebo of IR tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pelvic Floor Muscles Training in Men Undergoing Radiotherapy for Prostate Cancer: Randomized Controlled Trial
Status: TERMINATED
Conditions: Prostate Cancer|Urologic Diseases
Interventions: OTHER: Pelvic floor muscles training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Postoperative Pain Control Following Hysteroscopy
Status: RECRUITING
Conditions: Postoperative Pain|Postoperative Nausea|Analgesia
Interventions: DRUG: Lidocaine IV|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Does Dietary Nitrate Supplementation Improve Aerobic Performance
Status: UNKNOWN
Conditions: Colorectal Cancer
Interventions: DIETARY_SUPPLEMENT: Beetroot juice|DIETARY_SUPPLEMENT: Placebo beetroot juice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Proactive Care Coordination for Cancer Survivors Who Smoke
Status: COMPLETED
Conditions: Cancer
Interventions: BEHAVIORAL: Online Referral NYS Quitline|BEHAVIORAL: Tobacco cessation counseling and coordination of cessation medications
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Hippotherapy Versus Swiss Ball Training to Improve Trunk Control and Balance on Spastic Daiplegic Cerebral Palsy
Status: RECRUITING
Conditions: Cerebral Palsy Spastic Diplegia
Interventions: OTHER: Hippotherapy|OTHER: Swiss Ball therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of IDP-121 and IDP-121 Vehicle Lotion in the Treatment of Acne Vulgaris
Status: COMPLETED
Conditions: Acne
Interventions: DRUG: IDP 121 Lotion|DRUG: IDP-121 Vehicle Lotion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Temperatures to Treat Insomnia
Status: COMPLETED
Conditions: Primary Insomnia
Interventions: DEVICE: Cereve Sleep System at 30 degrees C|DEVICE: Cereve Sleep System at 14-16 degrees C
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study Using Oral Capsule FMT to Decolonize GI CRE
Status: WITHDRAWN
Conditions: Enterobacteriaceae Infections|Fecal Microbiota Transplantation
Interventions: BIOLOGICAL: Fecal Microbiota Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Aerobic Exercise on Side Effects of Disease Modifying Therapy With Subcutaneous Interferon-b1b in Patients With Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: OTHER: Physical exercise training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Efficacy of Alcohol Hand-rubbing Covering All Hand Surfaces in Reducing Bacterial Hand Contamination of Healthcare Staff
Status: COMPLETED
Conditions: Efficacy of Hand Hygiene Protocols
Interventions: OTHER: Hand hygiene protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Efficacy Trial of N-Acetylcysteine and Sodium Bicarbonate for the Prevention of Contrast-Induced Acute Kidney Injury
Status: UNKNOWN
Conditions: Chronic Kidney Disease
Interventions: DRUG: Physiological Saline, N-Acetylcysteine and Sodium Bicarbonate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy Study of Fibrin Sealant Grifols as an Adjunct to Hemostasis During Peripheral Vascular Surgery
Status: COMPLETED
Conditions: Vascular Surgical Bleeding
Interventions: BIOLOGICAL: Fibrin Sealant Grifols|PROCEDURE: Manual Compression
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: Vitamin D Repletion in Primary Hyperparathyroidism
Status: COMPLETED
Conditions: Primary Hyperparathyroidism|Vitamin D Deficiency
Interventions: DRUG: 10,000 IU Vitamin D3|OTHER: Placebo|DIETARY_SUPPLEMENT: Vitamin D
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Novel Application of a Low-cost Alternative to Patient Specific Implants (PSI) in Mandibular Free Fibula Flap Reconstruction by Reverse Engineering of Stock Plates: A Pilot Validation Study
Status: RECRUITING
Conditions: Fibula / Surgery|Surgical Flaps|Computer-Aided Design|Mandibular Reconstruction* / Methods|Surgery, Computer-Assisted
Interventions: PROCEDURE: Computer guided placement of a stock plate pre-bent on a 3D printed model
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neuromuscular Responses to Recovery Techniques
Status: COMPLETED
Conditions: Muscle Soreness
Interventions: OTHER: Cold Water Immersion|DEVICE: Percussive Massage Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Intrathecal DepoCyte and Lineage-targeted Minimal Residual Disease-oriented Therapy of Acute Lymphoblastic Leukemia
Status: COMPLETED
Conditions: Acute Lymphoblastic Leukemia
Interventions: DRUG: liposome-encapsulated cytarabine (DepoCyte)|DRUG: Triple intrathecal therapy (TIT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SGLT2 Inhibitors, Ketogenesis, and Ketoacidosis
Status: RECRUITING
Conditions: Type 2 Diabetes|Type 1 Diabetes
Interventions: DRUG: Empagliflozin 25 MG|OTHER: Placebo|DRUG: Pioglitazone 30mg|DRUG: Pioglitazone 30mg + Empagliflozin (25 mg)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Multi-center Study for Eradication of Helicobacter Pylori With Triple Therapy Using Clarithromycin
Status: UNKNOWN
Conditions: Gastritis
Interventions: DEVICE: The results of clarithromycin susceptibility test of H. pylori isolates|DEVICE: Computer generated random number, randomly assigned into groups|DEVICE: The result of 13C-urea breath test of patient in 7days/10days/14days treatment groups
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fate of Nutrient-Derived Amino Acids, FONDAA
Status: COMPLETED
Conditions: Protein Utilization|Dietary Protein
Interventions: DIETARY_SUPPLEMENT: Meal serving at high dietary protein|DIETARY_SUPPLEMENT: Meal serving at low dietary protein|DIETARY_SUPPLEMENT: Meal serving
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: rhGH and rhIGF-1 Combination Therapy in Children With Short Stature Associated With IGF-1 Deficiency
Status: TERMINATED
Conditions: Insulin-like Growth Factor-1 Deficiency
Interventions: DRUG: NutropinAq® (Somatropin [rDNA origin])|DRUG: Increlex® (Mecasermin [rDNA origin] injection) + NutropinAq® (Somatropin [rDNA origin])|DRUG: Increlex® (Mecasermin [rDNA origin] injection) + NutropinAq® (Somatropin [rDNA origin])|DRUG: Increlex® (Mecasermin [rDNA origin] injection) + NutropinAq® (Somatropin [rDNA origin])
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Study in the Efficacy of Topical Besifloxocin With Erythromycin for the Management of Acute Blepharitis
Status: COMPLETED
Conditions: Blepharitis
Interventions: DRUG: Erythromycin|DRUG: Besifloxocin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aiming for a Better Understanding and Improvement of the Diagnosis and Prognosis of Patients With Disorders of Consciousness Through Multimodal Observations
Status: UNKNOWN
Conditions: Disorders of Consciousness|Minimally Conscious State|Unresponsive Wakefulness Syndrome|Caregivers
Interventions: BEHAVIORAL: Coma scales|DIAGNOSTIC_TEST: Imaging, electrophysiology, body signals, and brain stimulation|BEHAVIORAL: Questionnaires
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Lower Urinary Tract Dysfunction in Chronic Chagas' Disease : Clinical and Urodynamic Presentation
Status: COMPLETED
Conditions: Chagas' Disease (Chronic) With Other Organ Involvement
Interventions: DIAGNOSTIC_TEST: Chagas serology|BIOLOGICAL: Creatinina|PROCEDURE: Urodynamic exploration
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Molecule Basic Study of Early Warning for New Pathogenic Risk of Ankylosing Spondylitis
Status: COMPLETED
Conditions: Ankylosing Spondylitis
Interventions: BIOLOGICAL: MSC|DRUG: "celecoxib", "Celebrex®"
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Intra Oral Kinetics of Fluoride Containing Dentifrices
Status: COMPLETED
Conditions: Tooth Erosion
Interventions: OTHER: Test Dentifrice|OTHER: Reference Dentifrice|OTHER: Comparator Dentifrice|OTHER: Orange Juice|OTHER: De-ionised water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Weaning Protocol for High-flow Nasal Oxygen Therapy in Intensive Care
Status: RECRUITING
Conditions: Acute Hypoxemic Respiratory Failure|High-flow Nasal Oxygen Therapy
Interventions: DRUG: HFNO weaning protocol|DRUG: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Prospective, Randomized Trial of Basiliximab (Simulect) in the Prophylaxis of High-Risk Keratoplasty Patients
Status: COMPLETED
Conditions: Corneal Transplantation
Interventions: DRUG: Basiliximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Internet-delivered Treatment for Children With Anxiety Disorders in a Rural Area; an Open Trial in a Clinical Setting
Status: COMPLETED
Conditions: Specific Phobia|Separation Anxiety|Generalized Anxiety Disorder
Interventions: BEHAVIORAL: Internet-delivered Cognitive Behavior Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CATCH [Short Name for: Coil Application Trial in China]
Status: COMPLETED
Conditions: Intracranial Aneurysm
Interventions: DEVICE: Coil Embolization System|DEVICE: Cotrol device from Medronic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oxygen Toxicity: Mechanisms in Humans
Status: RECRUITING
Conditions: Oxygen Toxicity|Hypercapnia|Seizures
Interventions: BEHAVIORAL: Sleep Deprivation|DRUG: Caffeine|DRUG: Methylphenidate|DRUG: Carbon Dioxide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of Inhaled CHF6333 After Single Doses in Healthy Volunteers and After Single and Repeated Doses in Subjects With Bronchiectasis
Status: RECRUITING
Conditions: Bronchiectasis
Interventions: DRUG: CHF6333|DRUG: CHF6333 Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Safety, Tolerability, and Effect on Disease Progression of BIIB105 in Participants With Amyotrophic Lateral Sclerosis (ALS) and Participants With the ALS Ataxin-2 (ATXN2) Genetic Mutation
Status: ACTIVE_NOT_RECRUITING
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DRUG: BIIB105|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Intravenous GSK3858279 on a Battery of Evoked Pain Tests in Healthy Volunteers
Status: TERMINATED
Conditions: Pain
Interventions: DRUG: Placebo|DRUG: GSK3858279
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Use of Zinc in the Treatment of Acute Diarrhea in Infants
Status: COMPLETED
Conditions: Acute Diarrhea|Acute Gastroenteritis
Interventions: DRUG: Zinc Sulfate|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparison of the Alignment Achieved Using Computer-guided Indirect Bonding of Orthodontic Brackets to Conventional Appliance Placement
Status: UNKNOWN
Conditions: Malocclusion
Interventions: PROCEDURE: Motion View|PROCEDURE: Conventional Orthodontic Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Safety and Tolerability of Atorvastatin 40 mg in Patients With Relapsing-remitting Multiple Sclerosis Treated With Interferon-beta-1b
Status: COMPLETED
Conditions: Relapsing-remitting Multiple Sclerosis
Interventions: DRUG: Interferon beta-1b group|DRUG: Interferon beta-1b/Atorvastatin group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fundamental Modification of the Gut Microbiota in the Treatment of Refractory Crohn's Disease
Status: COMPLETED
Conditions: Crohn's Disease
Interventions: DRUG: Fluconazole|DRUG: Vancomycin|DRUG: Neomycin|DRUG: Ciprofloxacin|DRUG: Polyethylene Glycol 3350|DRUG: Promethazine|DRUG: Fluconazole placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Exploratory Safety Study of ALD518 in Subjects With Steroid-refractory Acute Graft Versus Host Disease (GVHD)
Status: TERMINATED
Conditions: Acute GvHD
Interventions: BIOLOGICAL: ALD518|BIOLOGICAL: ALD518|BIOLOGICAL: ALD518
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Chidamide Combined With BEAM Pretreatment Regimen in Autologous Transplantation for T-cell Lymphoma
Status: RECRUITING
Conditions: T Cell Lymphoma
Interventions: DRUG: Chidamide combined with BEAM
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Schizotypal Personality Disorder Risperidone
Status: COMPLETED
Conditions: Schizotypal Personality Disorder
Interventions: DRUG: Risperidone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect of "Laying on of Hands" in Older Women With Knee Osteoarthritis
Status: UNKNOWN
Conditions: Knee Osteoarthritis
Interventions: OTHER: Spiritual laying on of hands (SP)|OTHER: Non-spiritual Laying on of Hands|OTHER: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating the Abuse Potential of NEURONTIN® in Healthy Non-drug Dependent, Recreational Opioid Users
Status: COMPLETED
Conditions: Abuse Potential
Interventions: DRUG: gabapentin 600 mg|DRUG: gabapentin 1200 mg|DRUG: gabapentin 600 mg and oxycodone HCl 20 mg|DRUG: gabapentin 1200 mg and oxycodone HCl 20 mg|DRUG: oxycodone HCl 20 mg|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: DUAL Pathway Inhibition to Improve Endothelial Function in Peripheral Artery Disease
Status: COMPLETED
Conditions: Peripheral Artery Disease
Interventions: DRUG: Rivaroxaban 2.5 Mg Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Tolvaptan to Treat Patients With Cardiac Edema
Status: COMPLETED
Conditions: Cardiac Edema
Interventions: DRUG: Tolvaptan|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Sensitivity to Change of a Bimanual 3D Analysis Protocol for the Assessment of Upper Limb Movement in Children With Cerebral Palsy Before and After Therapies
Status: RECRUITING
Conditions: Cerebral Palsy Infantile
Interventions: PROCEDURE: HABIT ILE rehabilitation course|PROCEDURE: botulinum toxin injections
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Tocilizumab in Patients With Hepatocellular Carcinoma (HCC) Undergoing Transarterial Chemoembolization (TACE)
Status: WITHDRAWN
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Tocilizumab|PROCEDURE: Transcatheter Arterial Chemoembolization
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neurocognitive Basis of Attention and Eye Movement Guidance in the Real World Scenes
Status: WITHDRAWN
Conditions: Cognition|Attention|Eye Movements
Interventions: DEVICE: Electrical Brain Stimulation|DEVICE: Sham Electrical Brain Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Ovarian Hyperstimulation Syndrome and Cabergoline
Status: COMPLETED
Conditions: Polycystic Ovarian Syndrome|Ovarian Hyperstimulation Syndrome
Interventions: DRUG: Cabergoline
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Aliskiren, Ramipril, and the Combination on Levels of Angiotensin II in Patients With Decompensated Systolic Heart Failure
Status: COMPLETED
Conditions: Heart Failure
Interventions: DRUG: aliskiren|DRUG: ramipril|DRUG: Placebo to aliskiren|DRUG: Placebo to ramipril
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Eliminate Hib Carriage in Rural Alaska Native Villages
Status: COMPLETED
Conditions: Haemophilus Influenzae Type B|Carrier State
Interventions: BIOLOGICAL: Hib conjugate vaccine (HbOC, Wyeth Vaccines)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Safety and Tolerability Study of Paliperidone Palmitate Injected in the Shoulder or the Buttock Muscle in Patients With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: paliperidone palmitate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Assessing Childbirth-related Complications at the Community Level in Kenya
Status: COMPLETED
Conditions: Puerperal Sepsis|Postpartum Hemorrhage|Preeclampsia and Eclampsia|Retained Placenta, Without Hemorrhage|Obstructed Labor Due to Breech Presentation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Electrical Stimulation of the Muscle Pumps of the Leg
Status: COMPLETED
Conditions: Haemodynamic Physiology
Interventions: DEVICE: Electrical stimulation (Digitimer)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: IRB-HSR# 14145 R,S Methadone: Analgesia and Pharmacokinetics in Adolescents Undergoing Scoliosis Correction
Status: COMPLETED
Conditions: Scoliosis
Interventions: DRUG: methadone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effect of Ascorbic Acid Supplementation in Pregnancy on Anemia (AAA)
Status: WITHDRAWN
Conditions: Anemia in Pregnancy
Interventions: DIETARY_SUPPLEMENT: Vitamin C
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Mismatched Related Donor Versus Matched Unrelated Donor Stem Cell Transplantation for Children, Adolescents, and Young Adults With Acute Leukemia or Myelodysplastic Syndrome
Status: RECRUITING
Conditions: Acute Lymphoblastic Leukemia|Acute Myeloid Leukemia|Mixed Phenotype Acute Leukemia|Myelodysplastic Syndrome
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Bone Marrow Aspiration|DRUG: Busulfan|DRUG: Cyclophosphamide|PROCEDURE: Echocardiography|DRUG: Fludarabine|PROCEDURE: Haploidentical Hematopoietic Cell Transplantation|BIOLOGICAL: Lapine T-Lymphocyte Immune Globulin|PROCEDURE: Lumbar Puncture|PROCEDURE: Matched Unrelated Donor Hematopoietic Cell Transplantation|DRUG: Melphalan|DRUG: Methotrexate|PROCEDURE: Multigated Acquisition Scan|DRUG: Mycophenolate Mofetil|PROCEDURE: Myeloablative Conditioning|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration|BIOLOGICAL: Rituximab|PROCEDURE: T-Cell Depletion Therapy|DRUG: Tacrolimus|DRUG: Thiotepa|RADIATION: Total-Body Irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunization Strategy With Intra-tumoral Injections of Pexa-Vec With Ipilimumab in Metastatic / Advanced Solid Tumors.
Status: COMPLETED
Conditions: Metastatic Tumor|Advanced Tumor
Interventions: BIOLOGICAL: Pexa-Vec|DRUG: Ipilimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Concurrent Capecitabine-based Long-term Radiotherapy Followed by XELOX Plus TME in Patients With High Risk Rectal Cancer: a Multi-centers, Randomized Controlled, Open-Label Trial
Status: RECRUITING
Conditions: Rectal Cancer|Pathological Complete Response|Disease Free Survival
Interventions: DRUG: concurrent capecitabine-based long-term radiotherapy followed by 4 cycles XELOX and a delayed TME|DRUG: concurrent capecitabine-based long-term radiotherapy followed by a Regular TME and 6 Cycles XELOX
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I/IIa Trial to Investigate BI 6727 (Volasertib) as Monotherapy or in Combination With Cytarabine in Acute Myeloid Leukaemia
Status: COMPLETED
Conditions: Leukemia, Myeloid, Acute
Interventions: DRUG: Volasertib|DRUG: Cytarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endodontic Medications for Irreversible Pulpitis: Articaine or Eugenol?
Status: COMPLETED
Conditions: Pulpitides|Endodontic Inflammation|Toothaches|Operative Dentistry
Interventions: DRUG: Implementation of a pulp medication in compliance with the dental emergency management protocol: articaïne|DRUG: Implementation of a pulp medication in compliance with the dental emergency management protocol: eugenol
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation and Treatment of Substance Abuse in Veterans With PTSD Disability Claims
Status: COMPLETED
Conditions: Attendance at Treatment|PTSD, Substance Use, and Attendance at Treatment
Interventions: BEHAVIORAL: SBIRT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Prospective Trial of Non-healing Diabetic Foot Ulcers Treated With Standard Care With or Without BR-AM
Status: NOT_YET_RECRUITING
Conditions: Non-infected Diabetic Foot Ulcer|Diabetic Foot|Diabetic Wound|Diabetic Foot Ulcer|Non-ischemic Diabetic Foot Ulcer
Interventions: OTHER: BR-AM|OTHER: Standard Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Prospective Pilot Study to Explore Efficacy and Safety of Baricitinib in Active Primary Sjogren's Syndrome Patients
Status: COMPLETED
Conditions: Sjogren's Syndrome
Interventions: DRUG: Baricitinib 2 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Westlake Precision Birth Cohort
Status: ACTIVE_NOT_RECRUITING
Conditions: Diabetes, Gestational|Pregnancy in Diabetics|Intrauterine Hyperglycemia
Interventions: OTHER: Standardized breakfast|OTHER: Standardized snack|OTHER: Standardized lunch
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effect of Stress Ball Utilisation on Treatment Duration, Dyspnea Severity and Anxiety Level in Nebuliser Therapy
Status: RECRUITING
Conditions: Inhalation Therapy; Complications
Interventions: DEVICE: Stress ball
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Perioperative Acetaminophen Dosing on Patients Undergoing Surgical Treatment of Basilar Thumb Arthritis
Status: RECRUITING
Conditions: Carpometacarpal Osteoarthritis
Interventions: DRUG: Acetaminophen|OTHER: Placebo: Multivitamin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Early Treatments for Preventing Occlusal Caries Lesions
Status: RECRUITING
Conditions: Caries; Initial|Occlusal Caries|Caries,Dental
Interventions: DRUG: Fluoride varnish|DRUG: Conventional etch and rinse sealant|DRUG: Self-etch sealant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Efficacy and Safety of Tocilizumab in Participants With Systemic Sclerosis (SSc)
Status: COMPLETED
Conditions: Systemic Sclerosis
Interventions: DRUG: Placebo|DRUG: Tocilizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Neuromuscular Electrical Stimulation and Ultrasound Therapies , Knee Osteoarthritis
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: OTHER: ultrasound therapy|OTHER: neuromuscular electrical stimulation application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT