pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Effect of Task-oriented Training Assisted by Force Feedback Hand Rehabilitation Robot on Finger Function in Stroke Patients With Hemiplegia
Status: RECRUITING
Conditions: Stroke
Interventions: DEVICE: force feedback rehabilitation robot (SEM™ Glove)|OTHER: assisted by a therapist
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of VIUSID® Plus GLIZIGEN® in Patients With Papilloma Virus Esophageal
Status: COMPLETED
Conditions: Papilloma Viral Infection|Papillomavirus Infections|Esophageal Viral Wart|Esophageal Verrucous Carcinoma
Interventions: DIETARY_SUPPLEMENT: Viusid®|DIETARY_SUPPLEMENT: Glizigen®|DIETARY_SUPPLEMENT: Viusid Placebo|DIETARY_SUPPLEMENT: Glizigen Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II Gallium Nitrate in Relapsed or Refractory Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Non-Hodgkin's Lymphoma|Relapsed Lymphoma|Refractory Lymphoma|Low-Grade Lymphoma|Intermediate-Grade Lymphoma
Interventions: DRUG: gallium nitrate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Figitumumab Combined With Pegvisomant For Advanced Solid Tumors
Status: TERMINATED
Conditions: Colorectal Neoplasms|Lung Neoplasms|Breast Neoplasms|Prostatic Neoplasms|Sarcoma
Interventions: DRUG: figitumumab|DRUG: pegvisomant
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: First in Human SAD/MAD Safety and PK Study With Adult DMD Safety and PK Cohort
Status: RECRUITING
Conditions: Duchenne Muscular Dystrophy
Interventions: DRUG: SAT-3247|DRUG: matched placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Split-Face Tolerability Comparison Between MetroGel® 1% Versus Finacea® 15% in Subjects With Healthy Skin
Status: COMPLETED
Conditions: Skin Manifestations
Interventions: DRUG: metronidazole 1% gel|DRUG: azelaic acid 15% gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Acupuncture in Reducing the Severity of Chemoradiation-induced Mucositis in Patients With Oropharyngeal Cancer
Status: TERMINATED
Conditions: Mucositis|Oropharyngeal Cancer
Interventions: DEVICE: Acupuncture with Seirin® needles|OTHER: Usual medical care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Three Different Schedules of Low-Dose Decitabine in Myelodysplastic Syndrome (MDS)
Status: COMPLETED
Conditions: Myelodysplastic Syndrome|Chronic Myelomonocytic Leukemia
Interventions: DRUG: Decitabine|DRUG: Decitabine|DRUG: Decitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Post Approval Study Investigating Lutonix Drug Coated Balloon for Treatment of Dysfunctional Arteriovenous Fistulae
Status: RECRUITING
Conditions: Arteriovenous Fistula
Interventions: DEVICE: LUTONIX 035 Drug Coated Balloon PTA Catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Online Physical Therapy Management for Physiotherapists to Cope Psychological Distress During Covid-19 Pandemic
Status: COMPLETED
Conditions: Psychological Distress
Interventions: OTHER: Insula treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Stockholm Myocardial Infarction With Nonobstructive Coronaries Study 3
Status: RECRUITING
Conditions: Myocardial Infarction With Nonobstructive Coronary Arteries
Interventions: DIAGNOSTIC_TEST: Cardiac magnetic resonance imaging to study coronary microvascular dysfunction
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Intermittent Fasting for the Improvement of Outcomes in Patients With Stage I-III Breast Cancer Receiving Chemotherapy Before Surgery
Status: SUSPENDED
Conditions: Anatomic Stage I Breast Cancer AJCC v8|Anatomic Stage II Breast Cancer AJCC v8|Anatomic Stage III Breast Cancer AJCC v8|Breast Ductal Carcinoma in Situ|HER2 Negative Breast Carcinoma|Hormone Receptor Positive Breast Carcinoma|Invasive Breast Carcinoma
Interventions: OTHER: Short-Term Fasting
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of DW Silicone Hydrogel Lens Compared to DW Silicone Hydrogel Lens
Status: TERMINATED
Conditions: Myopia
Interventions: DEVICE: senfilcon A contact lens|DEVICE: investigational enfilcon A
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Radicle Rest 2: A Study of Health and Wellness Products on Sleep and Health Outcomes
Status: COMPLETED
Conditions: Sleep|Sleep Disturbance|Sleep Disorder
Interventions: DIETARY_SUPPLEMENT: Rest Study Active Product 1.1 Usage|DIETARY_SUPPLEMENT: Rest Study Active Product 1.2 Usage|DIETARY_SUPPLEMENT: Rest Study Active Product 2.1 Usage|DIETARY_SUPPLEMENT: Rest Study Active Product 2.2 Usage|DIETARY_SUPPLEMENT: Placebo Control Form 1|DIETARY_SUPPLEMENT: Placebo Control Form 2|DIETARY_SUPPLEMENT: Placebo Control Form 3|DIETARY_SUPPLEMENT: Rest Study Active Product 3.1 Usage|DIETARY_SUPPLEMENT: Placebo Control Form 4|DIETARY_SUPPLEMENT: Rest Study Active Product 4.1 Usage|DIETARY_SUPPLEMENT: Rest Study Active Product 4.2 Usage|DIETARY_SUPPLEMENT: Rest Study Active Product 4.3 Usage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Pediatric Type III Supracondylar Humeral Fracture
Status: COMPLETED
Conditions: Supracondylar Humerus Fracture|Pediatric Fractures
Interventions: PROCEDURE: Pediatric Garthland Type 3 supracondylar humeral fractures fixed by K-wires
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Strategies to Optimize Positive End-expiratory Pressure (PEEP) in Patients With Acute Lung Injury
Status: UNKNOWN
Conditions: Acute Lung Injury|Acute Respiratory Distress Syndrome|Respiratory Failure
Interventions: PROCEDURE: PEEP titration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Breech Pelvimetry by EOS® Technique With Change of Maternal Position and Delivery Route
Status: RECRUITING
Conditions: EOS|Pregnancy Related|Fetus Fetus|Breech Fetal Presentation
Interventions: DEVICE: EOS
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety and Efficacy Study of IGF-1 in Duchenne Muscular Dystrophy
Status: COMPLETED
Conditions: Duchenne Muscular Dystrophy
Interventions: DRUG: IGF-1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of BHV-7000 Monotherapy in Major Depression
Status: RECRUITING
Conditions: Major Depressive Disorder
Interventions: DRUG: BHV-7000|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I Clinical Trial to Evaluate the Safety of Recombinant Mycobacterium Tuberculosis Fusion Protein (EEC) in Healthy Adults Aged 18-65 and Patients With Pulmonary Tuberculosis
Status: COMPLETED
Conditions: Tuberculosis
Interventions: BIOLOGICAL: Recombinant Mycobacterium Tuberculosis Fusion Protein (EEC)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Impact of Polymorphisms of OCT2 and OCTN1 on the Kinetic Disposition of Gabapentin in Patients Undergoing Chronic Use
Status: COMPLETED
Conditions: Epilepsy|Chronic Pain
Interventions: PROCEDURE: Sparse blood sampling|PROCEDURE: Urine sampling|PROCEDURE: DNA extraction|DRUG: Gabapentin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Kinesio-Taping and Ankle Instability in Recreational Runners
Status: COMPLETED
Conditions: Ankle Instability
Interventions: OTHER: Kinesio-taping|OTHER: exercises|OTHER: mixed kinesiotape plus exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase Ib/II Multicenter Open-label Study of Bemcentinib (BGB324) in Patients With AML or MDS
Status: UNKNOWN
Conditions: Acute Myeloid Leukemia|Myelodysplastic Syndromes
Interventions: DRUG: Bemcentinib|DRUG: Cytarabine|DRUG: Decitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Screening Strategy for Early Diagnosis of Silicosis in At-Risk Populations in Oklahoma
Status: COMPLETED
Conditions: Silicosis|Pneumoconiosis; Silica
Interventions: DIAGNOSTIC_TEST: Tuberculosis test|DIAGNOSTIC_TEST: Chest X-ray|DIAGNOSTIC_TEST: Pulmonary Function Test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Preoperative Oral Pregabalin Effect on Inhalational Anesthetic Requirements ln Hysterectomy Under General Anesthesia
Status: COMPLETED
Conditions: Hysterectomy
Interventions: DRUG: Pregabalin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Dose Linearity Study of the Labopharm Formulation of Tramadol HCl/Contramid®, 100 mg, 200 mg and 300 mg After A Single Oral Administration In Fasting Condition, In Healthy Human Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Tramadol HCl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: 24 VS 48-WEEK TREATMENT WITH PEG-IFN ALPHA-2A IN PATIENTS WITH GENOTYPE 2/3 CHRONIC HEPATITIS C
Status: WITHDRAWN
Conditions: Chronic Hepatitis C
Interventions: DRUG: pegylated interferon alpha 2a + ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Development of a Patient Centered Mental Health Intervention for Recent Veterans
Status: COMPLETED
Conditions: Stress Disorders, Post-Traumatic|Depression|Anxiety|Substance-Related Disorders
Interventions: BEHAVIORAL: person-centered mental health intervention|BEHAVIORAL: health and wellness
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Management of Malignant Pleural Effusion With Indwelling Pleural Catheter Versus Silver Nitrate Pleurodesis
Status: UNKNOWN
Conditions: Pleural Effusion, Malignant
Interventions: DRUG: Silver Nitrate|DEVICE: Indwelling Pleural Catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Temsirolimus in Combination With Gemcitabine in Previously Untreated Metastatic Pancreatic Cancer
Status: TERMINATED
Conditions: Pancreatic Adenocarcinoma
Interventions: DRUG: Temsirolimus|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Protein Supplementation in Extremely Preterm Infants Fed Human Milk
Status: ACTIVE_NOT_RECRUITING
Conditions: Prematurity; Extreme|Feeding Disorder Neonatal|Breast Milk Expression|Growth Failure|Microbial Colonization
Interventions: PROCEDURE: Protein-enriched human milk diet|PROCEDURE: Usual human milk diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Trebananib (AMG 386) in Combination With Docetaxel for Advanced Urothelial Carcinoma
Status: WITHDRAWN
Conditions: Urothelial Carcinoma
Interventions: DRUG: AMG 386|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effect of AZD8154 Administered Via Nebulizer Once Daily in Subjects With Mild Allergic Asthma Challenged With an Inhaled Allergen
Status: WITHDRAWN
Conditions: Asthma
Interventions: DRUG: AZD8154 nebulizer suspension, 20 mg/mL|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Sonalleve Fibroid Ablation Pivotal Clinical Trial for MR-HIFU of Uterine Fibroids
Status: TERMINATED
Conditions: Uterine Fibroids
Interventions: DEVICE: MR-HIFU treatment|DEVICE: Sham treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of High-Dose Methotrexate (HDM) Plus Doxorubicin to HDM Plus Etoposide-Ifosfamide in Osteosarcoma Children
Status: COMPLETED
Conditions: Osteosarcoma|Localised High Grade Osteosarcoma of the Limbs
Interventions: DRUG: Etoposide, Ifosfamide, Methotrexate|DRUG: Doxorubicin, Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open Anterograde Radical Prostatectomy Compared to Open Retrograde Technique
Status: COMPLETED
Conditions: Prostatic Cancer|Prostatic Neoplasm
Interventions: PROCEDURE: 1 Retrograde radical prostatectomy RRP|PROCEDURE: 2 Anterograde radical prostatectomy RRP2A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Complarate® (Tocilizumab Biosimilar) and Actemra® in Patients With Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: BIOLOGICAL: Complarate®|BIOLOGICAL: Actemra®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Impact of Red Cell Age on Product Utilization in the Chronically Transfused Outpatient Population
Status: UNKNOWN
Conditions: Bone Marrow Failure Syndrome
Interventions: OTHER: Fresh Human Red Blood Cells|OTHER: Aged Human Red Blood Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of HS-20117 Combined With Aumolertinib in Participants With Advanced Non-Squamous Non-Small Cell Lung Cancer
Status: NOT_YET_RECRUITING
Conditions: Non-Squamous Non-Small Cell Lung Cancer
Interventions: DRUG: HS-20117|DRUG: Aumolertinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TDF Dose Adjustment VS. Switching to TAF in TDF-experienced CHB Patients With Renal Impairment
Status: UNKNOWN
Conditions: Renal Insufficiency|Tenofovir
Interventions: DRUG: Switching to Tenofovir Alafenamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Docosahexaenoic Acid Supplementation of Women With Hypertension in Pregnancy to Improve Endothelial Health
Status: WITHDRAWN
Conditions: Hypertension in Pregnancy
Interventions: DIETARY_SUPPLEMENT: Docosahexaenoic acid 200 mg|DRUG: Docosahexaenoic acid 1000 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Factors Increasing Air Burden in Intravenous Tubing
Status: COMPLETED
Conditions: Air Embolism|Air Leakage|Air Burden
Interventions: DEVICE: ClearLine IV (formerly, AirPurge)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: An Evaluation of the Effectiveness of Dual Focus Soft Contact Lenses in Slowing Mypoia Progression
Status: COMPLETED
Conditions: Myopia
Interventions: DEVICE: Dual Focus Soft Contact Lens|DEVICE: Single Vision Soft Contact Lens
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Acute Effects of Vaping Nicotine on Cognition in Young Adults
Status: COMPLETED
Conditions: Nicotine Addiction|Vaping
Interventions: DRUG: Nicotine pod|DRUG: Placebo pod
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Association Between Pre-op Non-Selective Beta-Blockers and Hepatocellular Carcinoma Recurrence Post-Liver Transplant
Status: COMPLETED
Conditions: Hepatocellular Carcinoma Recurrent|Hepatocellular Carcinoma
Interventions: DRUG: Non-Selective Beta-Adrenoreceptor Agonists for Systemic Use
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Mesenchymal Stem Cells Transplantation in Newly Diagnosed Type-1 Diabetes Patients
Status: UNKNOWN
Conditions: Diabetes Mellitus|Diabetes Mellitus, Type 1|Diabetes Mellitus, Insulin-Dependent
Interventions: BIOLOGICAL: Intravenous Injection of autologous mesenchymal stem cells|OTHER: Intravenous injection of placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Laparoscopic Uterine Sparing Techniques Outcomes and Reinterventions
Status: COMPLETED
Conditions: Uterine Fibroids|Myomas
Interventions: PROCEDURE: Global Fibroid Ablation|PROCEDURE: Myomectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Why in Hospital After VATS Lobectomy
Status: COMPLETED
Conditions: Carcinoma, Non-Small-Cell Lung|Pain, Postoperative|Postoperative Nausea and Vomiting|Infection|Air Leakage|Atrial Fibrillation
Interventions: OTHER: Prolong in-hospital stay
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Ombitasvir /Paritaprevir/Ritonavir Plus Ribavirin on HCV GT4
Status: COMPLETED
Conditions: Hepatitis C Virus Infection
Interventions: DRUG: OBV/PTV/r) ± ribavirin (RBV)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Do Extraperitoneal Laparoscopic Surgeries Increase Intracranial Pressure?
Status: COMPLETED
Conditions: Intracranial Pressure Increase
Interventions: DEVICE: E-CUBE i7 ultrasound system (Alpinion Medical Systems, Seoul, Republic of Korea)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Trial to Learn if Receiving ALN-PNP siRNA is Safe and Well Tolerated, and How it Works in Adult Participants With Nonalcoholic Fatty Liver Disease (NAFLD) and a Genetic Risk Factor
Status: RECRUITING
Conditions: Nonalcoholic Fatty Liver Disease (NAFLD)|Nonalcoholic Steatohepatitis (NASH)|Genetic Risk Factor
Interventions: DRUG: ALN-PNP|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Technolas 217z Laser With Zyoptix Aspheric Algorithm Used for the LASIK Treatment of Myopia and Myopic Astigmatism.
Status: COMPLETED
Conditions: Myopia|Astigmatism
Interventions: DEVICE: Bausch & Lomb 217z Excimer Laser
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Medical Thoracoscopy Versus Simple Chest Tube Drainage in Complicated Parapneumonic Effusion and Pleural Empyema
Status: TERMINATED
Conditions: Complicated Parapneumonic Effusion|Pleural Empyema
Interventions: PROCEDURE: Medical thoracoscopy|PROCEDURE: Simple chest tube drainage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of 2% Chlorhexidine Cloths Reduce Surgical Site Infections
Status: COMPLETED
Conditions: Surgical Site Infection
Interventions: DRUG: 2% Chlorohexidine Gluconate Standard of Care|DRUG: 2% Chlorohexidine Gluconate Chin to Toe
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Intensified Treatments for Patients With Locally Advanced Nasopharyngeal Carcinoma With Detectable EBV DNA After One Cycle GP Regime Neoadjuvant Chemotherapy
Status: RECRUITING
Conditions: Nasopharyngeal Carcinoma
Interventions: DRUG: Camrelizumab|DRUG: Nimotuzumab|DRUG: neoadjuvant chemotherapy and CCRT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Moderate Rheumatoid Arthritis (RA) With Etanercept (Enbrel)
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: etanercept|DRUG: Placebo|DRUG: DMARD Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of PET-CT Using Somatostatin Agonists Labeled With Gallium68 in Neuroendocrine Tumors
Status: COMPLETED
Conditions: Gastro-Entero-Pancreatic Tumors (GEPs)
Interventions: OTHER: PET-CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of Iopofosine I 131 (CLR 131) in Select B-Cell Malignancies (CLOVER-1) and Pivotal Expansion in Waldenstrom Macroglobulinemia
Status: RECRUITING
Conditions: Waldenstrom Macroglobulinemia|Multiple Myeloma|Chronic Lymphocytic Leukemia|Small Lymphocytic Lymphoma|Lymphoplasmacytic Lymphoma|Marginal Zone Lymphoma|Mantle Cell Lymphoma|Diffuse Large B Cell Lymphoma|Central Nervous System Lymphoma
Interventions: DRUG: Iopofosine I 131 single dose|DRUG: Iopofosine I 131 multiple dose|DRUG: Iopofosine I 131 fractionated dose
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Omalizumab to Treat Allergic Asthma
Status: COMPLETED
Conditions: Allergic Asthma
Interventions: DRUG: Omalizumab|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparison of High vs. Low Tidal Volumes in Ventilator Weaning for Individuals With Cervical Spinal Cord Injuries
Status: COMPLETED
Conditions: Spinal Cord Injury|Respiratory Insufficiency
Interventions: PROCEDURE: Tidal volume used in mechanical ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dynamic Navigation System in Implantology
Status: UNKNOWN
Conditions: Surgery, Computer-Assisted|Dental Implants
Interventions: DEVICE: Dynamic navigation system|DEVICE: Freehand implant placement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Head-up Tilt Test in Patients With Reflex Syncope and Asystolic Response Who Received a Dual-chamber Pacemaker With the Closed Loop Stimulation (CLS) and Participated in the BIOSync Trial
Status: COMPLETED
Conditions: Syncope|Syncope, Vasovagal
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Two Induction Regimens Using Topical Lidocaine or Muscle Relaxant on Sore Throat and Hemodynamics
Status: UNKNOWN
Conditions: Intubation Complication
Interventions: DRUG: Lidocaine spray (2%)|DRUG: Muscle Relaxant (Rocuronium)|OTHER: No Muscle relaxant, no Lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pain Control for Intrauterine Device Placement Using Paracervical Block
Status: COMPLETED
Conditions: Pain Due to Intrauterine Contraceptive Device
Interventions: PROCEDURE: Paracervical Block (PCB)|PROCEDURE: No Paracervical Block (Sham PCB)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Enhancement of Learning and Memory Following Supplementation With Juice PLUS+® OMEGA in an Adolescent Population
Status: COMPLETED
Conditions: Cognitive Change|Development, Adolescent
Interventions: DIETARY_SUPPLEMENT: Juice PLUS+® OMEGA|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Colesevelam Hydrogen Chloride (HCl) Powder For Oral Suspension Versus Generic Cholestyramine Through Use of the Bile Acid Sequestrant Acceptability (BASA) Scale
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Cholestyramine|DRUG: Colesevelam HCl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: MSB0010445 and Stereotactic Body Radiation Therapy in Advanced Melanoma
Status: TERMINATED
Conditions: Melanoma
Interventions: DRUG: MSB0010445 (0.3 milligram per kilogram [mg/kg])|DRUG: MSB0010445 (1.0 mg/kg)|DRUG: MSB0010445 (1.8 mg/kg)|DRUG: MSB0010445 (2.4 mg/kg)|RADIATION: Stereotactic Body Radiation Therapy (SBRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CyberKnife Based Hypofractionated Radiotherapy for Vertebral Hemangiomas
Status: UNKNOWN
Conditions: Hemangioma of Vertebral Column
Interventions: RADIATION: Cybernetic microradiosurgery|RADIATION: Conventional radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cardiac Arrhythmia Telemetry; Conventional vs HeartWatch
Status: ACTIVE_NOT_RECRUITING
Conditions: Cardiac Arrhythmia|Diagnostic/Monitoring Devices Related to Adverse Incidents
Interventions: DEVICE: HeartWatch
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Pharmacokinetic Study of Ustekinumab in Pediatric Subjects With Moderately to Severely Active Crohn's Disease
Status: COMPLETED
Conditions: Crohn Disease
Interventions: DRUG: Ustekinumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Omega-3 PUFA in Prevention of Cardiovascular and Metabolic Diseases (CARDMET3)
Status: UNKNOWN
Conditions: Obesity, Abdominal|Metabolic Syndrome|Cardiovascular Risk Factor
Interventions: DIETARY_SUPPLEMENT: Chia seeds supplementation (25 g)|DIETARY_SUPPLEMENT: Chia seeds supplementation (15 g)|DIETARY_SUPPLEMENT: Combine supplementation: chia seeds (15g) and fish oil Maxi Cor 70+20|DIETARY_SUPPLEMENT: Fish oil supplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: VGX-3100 and Electroporation in Treating Patients With HIV-Positive High-Grade Anal Lesions
Status: RECRUITING
Conditions: Anal Intraepithelial Neoplasia|High Grade Squamous Intraepithelial Neoplasia|HIV Positivity|Human Papillomavirus-16 Positive|Human Papillomavirus-18 Positive
Interventions: DEVICE: Electroporation|BIOLOGICAL: HPV DNA Plasmids Therapeutic Vaccine VGX-3100|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intensified Multifactorial Intervention in Patients With Type 2 Diabetes and Microalbuminuria
Status: ACTIVE_NOT_RECRUITING
Conditions: Type 2 Diabetes
Interventions: BEHAVIORAL: Diet|BEHAVIORAL: Exercise|BEHAVIORAL: Stop smoking|DRUG: Glucose lowering therapy|DRUG: Blood pressure lowering therapy|DRUG: Lipid lowering therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assess the Effects of Spectacles or Orthokeratology on Dry Eye Parameters in Children and Adolescents.
Status: NOT_YET_RECRUITING
Conditions: Dry Eye Disease
Interventions: DEVICE: Orthokeratology|DEVICE: Spectacles
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Efficacy of Different Treatment Methods in Patients With Carpal Tunnel Syndrome
Status: ACTIVE_NOT_RECRUITING
Conditions: Carpal Tunnel Syndrome
Interventions: DEVICE: Static wrist splint treatment|OTHER: Tendon and nerve gliding exercises|DRUG: Wrist local steroid injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sinopsys Lacrimal Stent Study for Patients With Chronic Sinusitis or CRS
Status: SUSPENDED
Conditions: Chronic Sinus Infection
Interventions: DEVICE: Sinopsys® Lacrimal Stent
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Nitrendipine/Atenolol Combination on Blood Pressure Variability.
Status: RECRUITING
Conditions: Hypertension
Interventions: DRUG: Nitrendipine/Atenolol|DRUG: Nitrendipine|DRUG: Atenolol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Gemcitabine/Cisplatin Plus Cemiplimab (REGN2810, Anti-PD-1) With or Without Fianlimab (REGN3767, Anti-LAG-3) in Patients With Localized Muscle-invasive Bladder Cancer (NeoSTOP-IT)
Status: NOT_YET_RECRUITING
Conditions: Bladder Cancer|Muscle-Invasive Bladder Carcinoma
Interventions: DRUG: Gemcitabine|DRUG: Cisplatin|DRUG: Cemiplimab|DRUG: Fianlimab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: On Open-Label Study in Participants With Systemic Lupus Erythematosus
Status: TERMINATED
Conditions: Systemic Lupus Erythematosus|Connective Tissue Disease|Autoimmune Disease
Interventions: DRUG: LY2127399|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Effectiveness of Low Molecular Weight Sulfated Dextran in Islet Transplantation
Status: COMPLETED
Conditions: Diabetes Mellitus, Type I
Interventions: DRUG: Low Molecular Weight Sulfated Dextran (LMW-SD)|DRUG: Heparin|DRUG: CellCept® (Mycophenolate mofetil) OR Rapamune® (Sirolimus)|DRUG: Prograf® (Tacrolimus) OR Cyclosporine|DRUG: Thymoglobulin® (Anti-thymocyte Globulin) - at first transplant|DRUG: Simulect® (Basiliximab) - at 2nd or 3rd transplant|DRUG: Klexane® (Enoxaparinsodium)|DRUG: Trombyl® or Albyl-E® (Acetylsalicylicacid- ASA)|DRUG: Enbrel® (Etanercept)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Type and Frequency of Nasal Irrigation in Rhinosinusitis Patients
Status: UNKNOWN
Conditions: Otorhinolaryngologic Diseases|Rhinosinusitis
Interventions: DRUG: Isotonic Saline ( 0.9% Sodium Chloride Saline)|DRUG: Hypertonic Saline ( 3% Sodium Chloride Saline)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of the Safety and Effectiveness of Treating Advanced AIDS Patients Between Ages 4 and 22 With 7 Drugs, Some at Higher Than Usual Doses
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Ritonavir|DRUG: Nelfinavir mesylate|DRUG: Saquinavir|DRUG: Nevirapine|DRUG: Lamivudine|DRUG: Stavudine|DRUG: Didanosine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: SEvoflurane for Sedation in ARds
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Respiratory Distress Syndrome
Interventions: DRUG: Inhaled sedation with sevoflurane|DRUG: intravenous sedation with propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cognitive Retraining and Brain Stimulation for Alcohol Use
Status: COMPLETED
Conditions: Binge Drinking
Interventions: BEHAVIORAL: Active Retraining|DEVICE: Sham TDCS|DEVICE: Active TDCS|BEHAVIORAL: Sham Retraining
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Improving Adherence to Post PCI Antiplatelet Therapy in Minority Populations
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: BEHAVIORAL: Motivational Interviewing (MINT)|BEHAVIORAL: Mailed DVD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: This Study is a Phase II Study of AZD6738 in Combination With Durvalumab in Patients With Solid Tumor (Cohort A (N=30): GC Who Have Failed Secondary Chemotherapy Treatments Regimen; Cohort B (B=30): Melanoma Patients Who Have Failed to IO)
Status: UNKNOWN
Conditions: Gastric Adenocarcinoma|Malignant Melanoma
Interventions: DRUG: AZD6738|DRUG: Durvalumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: DASH Diet Intervention at Senior Centers
Status: COMPLETED
Conditions: Hypertension
Interventions: BEHAVIORAL: Revision of congregate meal menus and recipes to align with parameters of DASH eating plan|BEHAVIORAL: On-site blood pressure monitoring|BEHAVIORAL: Home self blood pressure monitoring|BEHAVIORAL: Medical adherence education|BEHAVIORAL: Nutrition Education
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study of Cobalt's Role in Excessive Erythrocytosis Among High Altitude Dwellers in Cerro de Pasco, Peru
Status: COMPLETED
Conditions: Erythrocytosis|Mountain Sickness
Interventions: DRUG: N-acetylcysteine|DRUG: Acetazolamide|DRUG: Placebo pills
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SBIRT Implementation for Adolescents in Urban Federally Qualified Health Centers
Status: COMPLETED
Conditions: Alcohol-induced Disorders|Drug Users|Tobacco Use Disorder
Interventions: BEHAVIORAL: The brief interventions are delivered by behavioral health counselors (Specialist)|BEHAVIORAL: The brief interventions are delivered by the primary care provider (Generalist)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Pivotal Trial to Establish the Efficacy and Safety of Algisyl in Patients With Moderate to Severe Heart Failure
Status: UNKNOWN
Conditions: Heart Failure|Dilated Cardiomyopathy|Heart Failure With Reduced Ejection Fraction
Interventions: DEVICE: Algisyl|DRUG: Standard Medical Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Restylane Vital for Skin Rejuvenation of Dorsal Hands
Status: COMPLETED
Conditions: Dorsal Hands
Interventions: DEVICE: Restylane Vital
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Efficacy of 0.75% Boric Acid Gel in Chronic Periodontitis
Status: COMPLETED
Conditions: Chronic Periodontitis
Interventions: DRUG: SRP plus boric acid gel|DRUG: SRP plus placebo gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dose Escalation Study of Radium-223 Dichloride in Patients With Advanced Skeletal Metastases
Status: COMPLETED
Conditions: Neoplasm Metastasis
Interventions: RADIATION: Radium-223 dichloride (BAY88-8223)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: LAA Clipping Versus NOACs to Prevent Stroke in Non-paroxysmal Atrial Fibrillation.
Status: RECRUITING
Conditions: Non-paroxysmal Atrial Fibrillation
Interventions: PROCEDURE: Thoracoscopic LAA clipping|DRUG: Novel oral anticoagulant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Concomitant Chemoradiotherapy (CCRT) With Weekly Docetaxel and Cisplatin for Locally Advanced Head and Neck Cancer
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: DRUG: CCRT with weekly docetaxel & cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SC-004 Alone or With ABBV-181 in Subjects With Epithelial Ovarian, Fallopian Tube, Primary Peritoneal and Endometrial Cancers
Status: TERMINATED
Conditions: Cancer
Interventions: DRUG: SC-004|DRUG: ABBV-181
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Therapeutic Treatment With Human Papillomavirus Quadrivalent Vaccine for Recurrent Respiratory Papillomatosis
Status: WITHDRAWN
Conditions: Recurrent Respiratory Papillomatosis
Interventions: BIOLOGICAL: Human Papillomavirus Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of MAPI+Camrelizumab Versus API+Apatinib Versus MAPI in Patients With a Poor Response to Preoperative Chemotherapy for Newly Diagnosed High-grade Osteosarcoma
Status: UNKNOWN
Conditions: Osteosarcoma|Survival|Chemotherapy Effect|Toxicity, Drug
Interventions: DRUG: MAPI chemotherapy|DRUG: Apatinib Mesylate|DRUG: Camrelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: In-Vivo Activated T-Cell Depletion to Prevent GVHD
Status: TERMINATED
Conditions: Acute Myelogenous Leukemia|Acute Lymphocytic Leukemia|Chronic Myelogenous Leukemia|Chronic Lymphocytic Leukemia|Myelodysplasia|Lymphoma, Non-Hodgkin's|Mantle-Cell Lymphoma|Hodgkin's Disease|Multiple Myeloma|Myelofibrosis
Interventions: DRUG: Cyclophosphamide|DRUG: Fludarabine|DRUG: Cyclosporine|DRUG: Mycophenolate mofetil|DRUG: Basiliximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mitochondria-targeted System Therapy Combined With Radiofrequency Ablation for Early-stage Non-small Cell Lung Cancer
Status: UNKNOWN
Conditions: Non Small Cell Lung Cancer
Interventions: OTHER: Mitochondria-targeted System Therapy Combined With Radiofrequency Ablation|PROCEDURE: Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Motilitone on Gastric Emptying in Patients With Functional Dyspepsia: Evaluation Using MRI Method
Status: UNKNOWN
Conditions: Dyspepsia
Interventions: DRUG: Placebo|DRUG: motilitone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Compression Anastomosis Using the Compression Anastomotic Ring-locking Procedure (CARP)
Status: COMPLETED
Conditions: Cancer|Polyp
Interventions: DEVICE: Compression anastomotic ring-locking procedure (CARP)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Testing a Virtual Mindfulness-Based Intervention to Improve Veterans' Health
Status: RECRUITING
Conditions: Depression
Interventions: BEHAVIORAL: RECLAIM - Reconnecting to Civilian Life using Activities that Improve Mindfulness
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Individualized Physical Exercise Training and Enhanced Protein Intake in Older Citizens During Municipality-based Rehabilitation
Status: COMPLETED
Conditions: Rehabilitation
Interventions: OTHER: Usual Care|OTHER: Usual Care with Protein Supplementation|OTHER: Individualized Physical Exercise Training with Protein Supplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Respiratory Training vs Interoceptive Exposure in the Treatment of Transdiagnostic Pathological Anxiety
Status: RECRUITING
Conditions: Anxiety Disorders|Trauma|Generalized Anxiety Disorder|Panic Disorder|Agoraphobia|Illness Anxiety Disorder|Social Anxiety Disorder|Posttraumatic Stress Disorder|Acute Stress Disorder|Adjustment Disorder With Anxious Mood
Interventions: BEHAVIORAL: Interoceptive Exposure|DEVICE: Capnometry-Guided Respiratory Intervention|BEHAVIORAL: Psycho-Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Umbrella Study in R/R PTCL Guided by Molecular Subtypes
Status: RECRUITING
Conditions: Peripheral T Cell Lymphoma
Interventions: DRUG: Azacitidine Injection|DRUG: Dasatinib|DRUG: Linperlisib|DRUG: Tucidinostat|DRUG: SHR2554|DRUG: Camrelizumab|DRUG: Apatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Canfosfamide in Refractory or Relapsed Mantle Cell, Diffuse Large B Cell Lymphoma and Multiple Myeloma
Status: COMPLETED
Conditions: Mantle Cell Lymphoma|B Cell Lymphoma|Multiple Myeloma
Interventions: DRUG: Canfosfamide HCl for injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multimedia Animations to Support Therapeutic Exercise for Rotator Cuff Shoulder Pain
Status: RECRUITING
Conditions: Rotator Cuff Impingement Syndrome|Rotator Cuff Tendinitis|Rotator Cuff Related Shoulder Pain
Interventions: OTHER: Therapeutic exercise program|OTHER: Multimedia animation information|OTHER: Paper-based information
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Does Prehabilitation Improve Outcome in Coloncancer Surgery?
Status: NOT_YET_RECRUITING
Conditions: Surgery--Complications
Interventions: OTHER: Prehabilitation and Immunonutrition|OTHER: Standard Care Arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Assess the Efficacy and Safety of TC-5214 as an Adjunct Therapy in Patients With Major Depressive Disorder.
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: TC-5214|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Orofacial Myofunctional Therapy on Mouth Air Leak in Patients With Sleep Apnea Treated With CPAP
Status: TERMINATED
Conditions: OSA|Apnea+Hypopnea
Interventions: BEHAVIORAL: Orofacial exercises and oropharyngeal functions
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Sativex(Registered Trademark) and Oral THC on Attention, Affect, Working Memory, Reversal Learning, Physiology and Brain Activation
Status: COMPLETED
Conditions: Cannabis|Dependence|Cannabis Abuse|Pharmacokinetics|fMRI
Interventions: DRUG: Sativex(Registered Trademark)|DRUG: THC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: OTHER
Clinical trial: CP-690,550 And Oral Contraception Drug-Drug Interaction Study
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: ethinyloestradiol (EE) and levonorgestrel (LN), CP-690,550 + ethinyloestradiol (EE) and levonorgestrel (LN)|DRUG: CP-690,550 + ethinyloestradiol (EE) and levonorgestrel (LN), ethinyloestradiol (EE) and levonorgestrel (LN)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Magnesium Oil Application on the Muscle Contractile Properties
Status: COMPLETED
Conditions: Magnesium|Skeletal Muscle Contraction Properties
Interventions: OTHER: Magnesium oil (BetterYou) dermal application|OTHER: Placebo Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER