pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Moderate Hypofractionated Boost to the Prostate With Pelvic RT in High Risk Prostate Cancer
Status: RECRUITING
Conditions: Prostate Cancer
Interventions: RADIATION: Moderate hypofractionated boost to the prostate with pelvic RT (external beam radiotherapy)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multicenter Randomized Parallel-group Study to Investigate the Efficacy of a Combination of Rosuvastatin and Fenofibrate in the Patients With Diabetes or Atherosclerotic Vascular Diseases With Metabolic Syndrome
Status: AVAILABLE
Conditions: Diabetes|CVD
Interventions: DRUG: Rosuvastatin,SFC fenofibrate
Study Type: EXPANDED_ACCESS
Clinical trial: A Study of DISC-3405 in Healthy Volunteers
Status: RECRUITING
Conditions: Healthy Volunteer
Interventions: DRUG: DISC-3405|DRUG: DISC-3405|DRUG: Placebo|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: PET Imaging Using 64Cu-Tz-SarAr and hu5B1-TCO in People With Pancreatic, Colorectal, Bladder Cancer or Cancers With Elevated CA19.9
Status: RECRUITING
Conditions: Pancreatic Cancer|Pancreatic Ductal Adenocarcinoma|Metastatic Pancreatic Ductal Adenocarcinoma|Primary Pancreatic Ductal Adenocarcinoma|Metastatic Pancreatic Cancer
Interventions: DIAGNOSTIC_TEST: PET Scan|DRUG: hu5B1-TCO|DRUG: 64Cu-Tz-SarAr|DIAGNOSTIC_TEST: Pharmacokinetics
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation of Dietary Milk Polar Lipids on Serum Cholesterol and Gut Microbiota in Healthy Adults
Status: COMPLETED
Conditions: Serum Cholesterol|Gut Microbiome
Interventions: OTHER: Milk Polar Lipids|OTHER: Milk Fat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Phase I/Ib Trial of LSZ102 Single Agent or LSZ102 + LEE011 or LSZ102 + BYL719 in ER+ Breast Cancers
Status: TERMINATED
Conditions: Advanced or Metastatic ER+ Breast Cancer
Interventions: DRUG: LSZ102|DRUG: LEE011|DRUG: BYL719
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Health of Babies Born From IVF Versus IVM at 5 Years Old
Status: RECRUITING
Conditions: Infertility|IVF|IVM|Development, Child
Interventions: OTHER: Developmental score according to The Ages & Stages Questionnaires®, Third Edition - ASQ®-3 and behavioural screening according to Strength and Difficulties Questionnaires (SDQ's)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of BiPAP and ٰIS in Reducing Post CABG Pulmonary Complications
Status: UNKNOWN
Conditions: Pulmonary Complications
Interventions: DEVICE: BiPAP|DEVICE: Incentive spirometry
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of FDC Regimen of Dapagliflozin/Metformin Compared to Co-administered Dual Therapy on Glycemic Control, Satisfaction and Adherence in Chinese Patients With T2DM
Status: RECRUITING
Conditions: Type 2 Diabetes Mellitus (T2DM)
Interventions: DRUG: Xigduo (Dapagliflozin and Metformin hydrochloride extended-release) tablets|DRUG: Dapagliflozin tablets and Metformin HCl extended-release tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of a Bolus of Clonidine Systemically Administered on the Excitability of the Spinal Motoneurons of the Lower Extremity
Status: UNKNOWN
Conditions: Intraoperative Neurophysiological Monitoring|Pain Management
Interventions: DRUG: Clonidine hydrochloride|OTHER: Single bolus of physiologic sodium chloride serum administered IV after induction and obtaining a stable anaesthetic level
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Combined Replacement Therapy With Levothyroxine and Liothyronine in Thyroidectomized Patients
Status: COMPLETED
Conditions: Hypothyroidism
Interventions: DRUG: Liothyronine|DRUG: Levothyroxin|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Nicotine Patch - Multidose Bioequivalence Study
Status: COMPLETED
Conditions: Healthy Smokers
Interventions: DRUG: V0116 transdermal patch (Test treatment )|DRUG: Nicotine transdermal patch (Reference treatment )
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Adapting and Implementing a Nurse Care Management Model to Care for Rural Patients With Chronic Pain
Status: ENROLLING_BY_INVITATION
Conditions: Chronic Pain
Interventions: BEHAVIORAL: Cognitive Behavioral Therapy (CBT)|BEHAVIORAL: Enhance Fitness|OTHER: Care Coordination
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Swedish BioFINDER - Memory Clinic Study
Status: RECRUITING
Conditions: Mild Dementia|Mild Cognitive Impairment|SCD|Alzheimer Disease|Lewy Body Disease|Frontotemporal Degeneration|Vascular Dementia
Interventions: DIAGNOSTIC_TEST: Plasma Amyloid Probability Score 2 (APS 2) score|DIAGNOSTIC_TEST: Plasma ptau217/nptau217|DIAGNOSTIC_TEST: Plasma ptau217|DIAGNOSTIC_TEST: Plasma neurofilament light (NfL)|DIAGNOSTIC_TEST: Plasma Ab42/Ab40
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Prophylactic Antibiotics Duration Towards Healing and Risk of Infection in Permanent Pacemaker (PPM) Installation
Status: RECRUITING
Conditions: Pacemaker Complication
Interventions: DRUG: Cefazolin 1000 MG Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of Safety, Tolerability, and Evidence of Activity of FCFD4514S Administered Monthly or Every Other Month to Patients With Geographic Atrophy
Status: COMPLETED
Conditions: Geographic Atrophy
Interventions: DRUG: FCFD4514S|DRUG: sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Feasibility and Safety of a Wireless Palpator
Status: NOT_YET_RECRUITING
Conditions: Lung Cancer|Thoracic Neoplasm
Interventions: DEVICE: Palpator|DEVICE: Grasper|DEVICE: Ultrasound|OTHER: Finger palpation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Glaucoma Eye Drop Instillation: Impact of Education
Status: TERMINATED
Conditions: Glaucoma, Open-Angle
Interventions: OTHER: Video education on proper eye drop instillation technique|OTHER: Placebo video education on healthy eating tips
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Administration of Warm Blood Cardioplegia With or Without Roller Pump
Status: COMPLETED
Conditions: Coronary Disease
Interventions: OTHER: No pump|OTHER: Pump|OTHER: Blood sample collection: after induction of anaesthesia (T0)|OTHER: Blood sample collection: after arrival at the ICU (T1)|OTHER: Blood sample collection: 4 hours in ICU (T2)|OTHER: Blood sample collection: the first postoperative day (T3)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Bioequivalence Study Between Capoten Versus Captopril Reference Product in Healthy Adult Participants Under Fasting Conditions
Status: WITHDRAWN
Conditions: Healthy Volunteers
Interventions: DRUG: Capoten|DRUG: Captopril
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cabozantinib or Paclitaxel in Treating Patients With Persistent or Recurrent Epithelial Ovarian, Fallopian Tube, or Primary Peritoneal Cavity Cancer
Status: COMPLETED
Conditions: Recurrent Fallopian Tube Carcinoma|Recurrent Ovarian Carcinoma|Recurrent Primary Peritoneal Carcinoma
Interventions: DRUG: Cabozantinib S-malate|OTHER: Laboratory Biomarker Analysis|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: OM202JP Clinical Study of KNP2002
Status: ACTIVE_NOT_RECRUITING
Conditions: Common Wart
Interventions: DRUG: KNP2002|DRUG: Placebo of KNP2002
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Extracorporeal Shock Wave Therapy, LASER Therapy and Cryotherapy in Patients Having Sacroiliitis
Status: NOT_YET_RECRUITING
Conditions: Sacroilitis
Interventions: OTHER: shock wave therapy|OTHER: LASER Therapy|OTHER: Cryotherapy|OTHER: Exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety of "Ticagrelor+ Warfarin"in Comparison With "Clopidogrel+Aspirin+Warfarin"
Status: COMPLETED
Conditions: Atrial Fibrillation|Coronary Artery Disease
Interventions: DRUG: Ticagrelor+Warfarin|DRUG: Clopidogrel+Aspirin+Warfarin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long Thoracic Nerve Blockade for Pain Treatment After Video-Assisted Thoracoscopic Surgery
Status: UNKNOWN
Conditions: Nerve Block|Video-Assisted Thoracic Surgery
Interventions: DRUG: Morphine Sulfate|DRUG: Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: RG2133 (2',3',5'-Tri-O-Acetyluridine) in Mitochondrial Disease
Status: TERMINATED
Conditions: Mitochondrial Diseases
Interventions: DRUG: RG2133 (2',3',5'-tri-O-acetyluridine)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Active Conventional Therapy Compared to Three Different Biologic Treatments in Early Rheumatoid Arthritis With Subsequent Dose Reduction
Status: UNKNOWN
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Non-biological DMARD's|BIOLOGICAL: Cimzia|BIOLOGICAL: Orencia|BIOLOGICAL: RoActemra
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intraventricular Rt-PA in Patients With Intraventricular Hemorrhage
Status: COMPLETED
Conditions: Cerebral Hemorrhage
Interventions: DRUG: Recombinant Tissue Plasminogen Activator (rt-PA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: The Safety and Efficacy of SYD-101 in Children With Myopia
Status: ACTIVE_NOT_RECRUITING
Conditions: Nearsightedness|Near Sightedness|Near-sightedness
Interventions: DRUG: SYD-101 Dose 1|DRUG: SYD-101 Dose 2|DRUG: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Transforaminal vs. Parasagittal Interlaminar Epidural Injection
Status: COMPLETED
Conditions: Spinal Stenosis
Interventions: PROCEDURE: epidural steroid (dexamethasone) injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Patient and Partner Intervention After an Implantable Cardioverter Defibrillator (ICD)
Status: COMPLETED
Conditions: Implantable Cardioverter Defibrillator (ICD)
Interventions: BEHAVIORAL: patient only|BEHAVIORAL: patient and partner intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prucalopride + Prucalopride Booster vs. Prucalopride + Picosalax Booster for the Colon Capsule
Status: COMPLETED
Conditions: Bowel Cleansing|Colon Capsule Completion Times
Interventions: DRUG: Prucalopride|PROCEDURE: Colon Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Patient Satisfaction and Retention of Upper Complete Denture Base Using Rapid Prototyping Versus a Conventional One
Status: UNKNOWN
Conditions: Complete Denture
Interventions: DEVICE: Rapid prototyping Denture base|DEVICE: Heat Cured Conventional Complete Denture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Controlled Trial Comparing the Efficacy of Aerosolized Pentamidine and Parenteral/Oral Sulfamethoxazole-Trimethoprim in the Treatment of Pneumocystis Carinii Pneumonia in AIDS
Status: COMPLETED
Conditions: Pneumonia, Pneumocystis Carinii|HIV Infections
Interventions: DRUG: Pentamidine isethionate|DRUG: Sulfamethoxazole-Trimethoprim
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: VE303 for Treatment of Hepatic Encephalopathy (HE)
Status: COMPLETED
Conditions: Cirrhosis|Hepatic Encephalopathy
Interventions: DRUG: Placebo|DRUG: VE303|DRUG: oral vancomycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Stereotactic Body Radiation Therapy Combined With Anti-PD-1 Antibody in Patients With Hepatocellular Carcinoma
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma
Interventions: RADIATION: anti-PD-1 antibody
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PATient Navigator to rEduce Readmissions
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease|Heart Failure|Sickle Cell Disease|Myocardial Infarction|Pneumonia
Interventions: BEHAVIORAL: Hospital usual care|BEHAVIORAL: Navigator intervention|BEHAVIORAL: Peer-led telephone support line
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Retrospective Study to Analyze the Efficacy and Safety of Trabectedin and Pegylated Liposomal Doxorubicin (PLD ) in the Treatment of Patients With Platinum-sensitive Recurrent Ovarian Cancer (ROC), According to SmPC
Status: COMPLETED
Conditions: Ovarian Epithelial Cancer Recurrent
Interventions: DRUG: Trabectedin and Pegylated Liposomal Doxorubicin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effectiveness of Pulmonary Vein Isolation in Prevention of Atrial Fibrillation Following Heart Bypass Surgery
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DEVICE: PVI with Medtronic's Cardioblate BP2 radiofrequency catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Intracranial Hypertension and Optic Nerve Sheath Diameter
Status: COMPLETED
Conditions: Cerebral Stroke|Cerebral Venous Thrombosis
Interventions: OTHER: ONSD ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety, Metabolism, and Antioxidant Activity of Silymarin and Green Tea Extract in Patients With Chronic Hepatitis C
Status: COMPLETED
Conditions: Chronic Hepatitis C|Oxidative Stress
Interventions: DRUG: silymarin|DIETARY_SUPPLEMENT: green tea extract (EGCG)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, and Preliminary Efficacy of HRS-7450 Injection in the Treatment of Acute Ischemic Stroke: a Multi-center, Randomized, Double-blind, Double-dummy, Placebo-controlled Clinical Trial
Status: NOT_YET_RECRUITING
Conditions: Acute Ischemic Stroke
Interventions: DRUG: HRS-7450|DRUG: 0.9% sodium chloride injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intestine-lung Axis of Cystic Fibrosis Patients Treated With the Combination Elexacaftor/Tezacaftor/Ivacaftor
Status: RECRUITING
Conditions: Cystic Fibrosis
Interventions: PROCEDURE: Sample collection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effect Of Somatosensory Perceptıon And Proprıoceptıon On Upper Extremıty Functıonal Skılls
Status: COMPLETED
Conditions: Cerebral Palsy|Somatosensory Disorders|Upper Extremity Dysfunction|Proprioceptive Disorders
Interventions: OTHER: assessment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Mycobacterium w in Superficial Transitional Cell Carcinoma of Bladder
Status: COMPLETED
Conditions: Bladder Cancer
Interventions: BIOLOGICAL: Mycobacterium w|BIOLOGICAL: BCG (Bacillus Calmette-Guerin)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The NOrdic-Baltic Randomized Registry Study for Evaluation of PCI in Chronic Total Coronary Occlusion
Status: RECRUITING
Conditions: Chronic Total Occlusion of Coronary Artery|Heart Failure|Angina Pectoris
Interventions: PROCEDURE: CTO PCI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: AXOS and Microbial Metabolites in CKD
Status: COMPLETED
Conditions: Chronic Kidney Disease
Interventions: DIETARY_SUPPLEMENT: Arabinoxylan-oligosaccharides|DIETARY_SUPPLEMENT: Maltodextrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Efficacy and Tolerability of Vilazodone in (GAD) Generalized Anxiety Disorder
Status: COMPLETED
Conditions: Generalized Anxiety Disorder
Interventions: DRUG: Placebo|DRUG: Vilazodone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Visceral Lymphatic Mapping Using Isosulfan Blue in Patients With Cancer of the Pancreas, Colon, Stomach, Small Intestine, or Gallbladder
Status: COMPLETED
Conditions: Colorectal Cancer|Gallbladder Cancer|Gastric Cancer|Pancreatic Cancer|Small Intestine Cancer
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: CD19/CD22 Bicistronic Chimeric Antigen Receptor (CAR) T Cells in Children and Young Adults With Recurrent or Refractory CD19/CD22-expressing B Cell Malignancies
Status: RECRUITING
Conditions: B-NHL|B-Non Hodgkin Lymphoma|Acute Lymphocytic Leukemia|Acute Lymphoblastic Leukemia|B-precursor ALL|B-All|Lymphoma, Non-Hodgkin|Leukemia, Lymphocytic, B Cell|B-Cell Lymphoma|B-Cell Leukemia|Acute Lymphoid Leukemia
Interventions: BIOLOGICAL: CD19/CD22-CAR-transduced T cells|DRUG: cyclophosphamide|DRUG: fludarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Zimberelimab and Quemliclustat in Combination With Chemotherapy for the Treatment of Patients With Borderline Resectable and Locally Advanced Pancreatic Adenocarcinoma
Status: SUSPENDED
Conditions: Borderline Resectable Pancreatic Adenocarcinoma|Locally Advanced Pancreatic Ductal Adenocarcinoma
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|PROCEDURE: Core Biopsy|DRUG: Fluorouracil|DRUG: Irinotecan|DRUG: Leucovorin|DRUG: Leucovorin Calcium|DRUG: Oxaliplatin|DRUG: Quemliclustat|DRUG: Zimberelimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Annual Study to Investigate Inactivated Subunit Influenza Vaccine Due to New Virus Strains for the 2010/2011 Season
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Trivalent influenza subunit vaccine Influvac
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of Pre-Operative Cyberknife in Patients With Potentially Resectable Pancreas Cancer
Status: UNKNOWN
Conditions: Pancreas Cancer|Pancreatic Cancer|Adenocarcinoma of the Pancreas|Pancreas Adenocarcinoma|Pancreatic Adenocarcinoma
Interventions: DRUG: Gemcitabine|RADIATION: Stereotactic Radiosurgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Topiramate as Adjunctive Therapy in Infants 1-24 Months for the Control of Partial Onset Seizures
Status: COMPLETED
Conditions: Partial Seizure Disorder|Epilepsy|Seizures
Interventions: DRUG: topiramate|DRUG: topiramate|DRUG: topiramate|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Adequacy of Anaesthesia for Colonoscopic Procedures
Status: COMPLETED
Conditions: Colonic Diseases, Functional
Interventions: DRUG: rescue fentanyl|DRUG: rescue propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy and Safety Study of REM-001 Photodynamic Therapy for Treatment of Cutaneous Metastatic Breast Cancer (CMBC)
Status: RECRUITING
Conditions: Cutaneous Breast Cancer
Interventions: COMBINATION_PRODUCT: REM-001 photodynamic therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Topical Bimatoprost in the Treatment of Migraine
Status: UNKNOWN
Conditions: Migraine Disorders|Headache Disorders
Interventions: DRUG: Bimatoprost Topical Solution|DRUG: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Randomized Clinical Study Based on Comparison Between Closure of Uterine Incision With Vicryl 2/0 Versus Vicryl 1 in Development of Uterine Niche.
Status: COMPLETED
Conditions: Cesarean Section; Dehiscence
Interventions: PROCEDURE: Vicryl 1|PROCEDURE: Vicryl 2/0
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Respiratory COVID-19: A Randomized, Sham-Controlled Study
Status: WITHDRAWN
Conditions: COVID-19 Pneumonia|Acute Respiratory Distress Syndrome|COVID-19 Acute Respiratory Distress Syndrome|COVID-19 Respiratory Infection
Interventions: DEVICE: UVA Light Emitting Catheter|DEVICE: Sham Control Catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of GX-I7 in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: GX-I7|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Surgery Versus Stereotactic Body Radiation Therapy for Stage up to IA2 (T1a or T1b) Non-small Cell Lung Cancer
Status: WITHDRAWN
Conditions: Non-small Cell Lung Cancer Stage I|Surgery|Stereotactic Body Radiation Therapy
Interventions: PROCEDURE: Anatomical Segmentectomy, Lobectomy or Bilobectomy|RADIATION: Stereotactic Body Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Perioperative Administration of Pregabalin for Pain After Septoplasty
Status: UNKNOWN
Conditions: Deviated Nasal Septum
Interventions: DRUG: Pregabalin (Lyrica)|DRUG: Vitamin complex (placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Investigate the Effect of Single Dose of AZD6094 (600 mg) on Cardiac Repolarization in Healthy Volunteers
Status: COMPLETED
Conditions: Solid Tumors
Interventions: DRUG: AZD6094 200 mg|OTHER: Placebo|DRUG: Moxifloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Therapeutic Potential of Omega-3 Fatty Acids Supplementation in Dry Macular Degeneration and Stargardt Disease
Status: COMPLETED
Conditions: Dry AMD|Stargardt Disease 1
Interventions: DIETARY_SUPPLEMENT: Madeos|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Additional Effect of Visual Feedback Along With AOT on Balance,Mobility and Cognition in CP
Status: COMPLETED
Conditions: Cerebral Palsy
Interventions: OTHER: Action Observation Therapy|OTHER: Action Observation Therapy along with visual feedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Parent-Mediated Intervention Targeting Insistence on Sameness for Autistic Children
Status: NOT_YET_RECRUITING
Conditions: Autism Spectrum Disorder|Autism
Interventions: BEHAVIORAL: Supportive Parenting for Anxious Childhood Emotions (SPACE) for insistence on sameness (IS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Non-drug Study Profiling Cutaneous Lupus
Status: COMPLETED
Conditions: Lupus Erythematosus, Cutaneous|Lupus Erythematosus, Systemic|Lupus Erythematosus, Discoid
Interventions: PROCEDURE: No intervention, skin biopsy|PROCEDURE: No intervention, blood collection|PROCEDURE: No intervention, urine collection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: CH14.18 1021 Antibody and IL2 After Haplo SCT in Children With Relapsed Neuroblastoma
Status: COMPLETED
Conditions: Neuroblastoma Recurrent
Interventions: DRUG: ch14.18/CHO
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Irreversible Electroporation (NanoKnife ®) and Immunotherapy for the Treatment of Stage IV Colorectal Cancer
Status: NOT_YET_RECRUITING
Conditions: Liver Metastasis Colon Cancer
Interventions: COMBINATION_PRODUCT: IRE plus checkpoint inhibitor|COMBINATION_PRODUCT: IRE plus Checkpoint Inhibitor plus CpG-ODN
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral TEAD Inhibitor Targeting the Hippo Pathway in Subjects With Advanced Solid Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Solid Tumors, Adult|Solid Tumor|Malignant Pleural Mesothelioma (MPM)|Epithelioid Hemangioendothelioma (EHE)|NF2 Deficient Mesothelioma|Other NF2 Deficient Solid Tumors and Solid Tumors With YAP1/TAZ Fusion Genes|NF2 Deficiency|YAP1 or TAZ Gene Fusions
Interventions: DRUG: IK-930|DRUG: Osimertinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fluid Lavage of Open Wounds (FLOW): Pilot Trial
Status: COMPLETED
Conditions: Infection|Wound Healing Problem|Nonunion
Interventions: PROCEDURE: Type of fluid lavage solution|PROCEDURE: Type of fluid lavage pressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Nivolumab and Chemotherapy Followed by Surgery for Mesothelioma
Status: ACTIVE_NOT_RECRUITING
Conditions: Malignant Pleural Mesothelioma
Interventions: DRUG: Nivolumab|DRUG: Pemetrexed|DRUG: Cisplatin or Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: IMPACT Study: A Study of Valcyte (Valganciclovir) for Prevention of Cytomegalovirus Disease (CMV) in Kidney Allograft Recipients
Status: COMPLETED
Conditions: Cytomegalovirus Infections
Interventions: DRUG: Valganciclovir|DRUG: Valganciclovir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Tomatis Auditory Stimulation in Children and Adolescents With NDDs
Status: RECRUITING
Conditions: Neurodevelopmental Disorders
Interventions: DEVICE: Tomatis auditory stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A First-in-human Study of IBI354 in Subjects With Locally Advanced Unresectable or Metastatic Solid Tumors
Status: NOT_YET_RECRUITING
Conditions: Locally Advanced Unresectable or Metastatic Solid Tumors
Interventions: BIOLOGICAL: IBI354
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of Recombinant Human Growth Hormone in Short Stature Children Due to Chronic Kidney Disease Before Transplantation
Status: UNKNOWN
Conditions: Dwarfism
Interventions: DRUG: Recombinant Human Growth Hormone Injection (rhGH)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Precise Aerosol Inhalation Nursing on Sputum Excretion in Elderly Patients With Lung Surgery
Status: UNKNOWN
Conditions: Inhalation
Interventions: BEHAVIORAL: Precise Aerosol Inhalation Nursing Program|BEHAVIORAL: Traditional Aerosol Inhalation Nursing Method
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Developing a Low-Intensity Primary Care Intervention for Anxiety Disorders (AIM-PC)
Status: COMPLETED
Conditions: Anxiety Disorders
Interventions: BEHAVIORAL: FaceAnxiety|BEHAVIORAL: Symptom Tracking
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transversus Abdominis Plane (TAP) Block Versus Intrathecal Morphine for Caesarean Section - Randomised Controlled Trial
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: OTHER: spinal anesthesia with intrathecal morphine|OTHER: TAP-block with ropivacaine and clonidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: AVAPERL1 Study: A Study of Avastin (Bevacizumab) With or Without Pemetrexed as Maintenance Therapy After Avastin in First Line in Patients With Non-Squamous Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Non-Squamous Non-Small Cell Lung Cancer
Interventions: DRUG: bevacizumab [Avastin]|DRUG: cisplatin|DRUG: pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Early and Late Time-restricted Eating on Overweight Adults With Metabolic Syndrome
Status: NOT_YET_RECRUITING
Conditions: Metabolic Syndrome|Overweight and Obesity|Time Restricted Eating
Interventions: BEHAVIORAL: Early time-restricted eating (eTRE)|BEHAVIORAL: Late time-restricted eating (lTRE)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 3, Open-label, Crossover Study to Evaluate Self-administration of Rozanolixizumab by Study Participants With Generalized Myasthenia Gravis (gMG)
Status: COMPLETED
Conditions: Generalized Myasthenia Gravis
Interventions: DRUG: Rozanolixizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Are Supervised Exercises and TENS Necessary Along With Prescribed Home Exercises for Chronic Low Back Pain?
Status: WITHDRAWN
Conditions: Chronic Low Back Pain
Interventions: DEVICE: TENS|OTHER: SMCE|OTHER: UHEP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Role Of Different Prophylactic Doses Of Intravenous Tranexamic Acid In Reducing Blood Loss At Caesarean Section
Status: COMPLETED
Conditions: Hemorrhage of Cesarean Section and/or Perineal Wound|Postpartum Hemorrhage
Interventions: DRUG: Normal Saline containing a prophylactic Antibiotic 1 g|DRUG: Tranexamic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Phase II Study of Perindopril and Regorafenib in mCRC
Status: COMPLETED
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: Regorafenib|DRUG: Perindopril
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of Pharmacology of Paracetamol Administered Per-oral Mucosa
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Kinetics of plasma concentrations of paracetamol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Commercially Available Footwear Interventions in Meniscectomy Patients
Status: COMPLETED
Conditions: Meniscus Injury|Osteoarthritis, Knee|Footwear
Interventions: DEVICE: Footwear|PROCEDURE: Gait analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Impact of Auricular Vagus Nerve Neuromodulation on COVID-19 Positive Inpatients Outcome
Status: TERMINATED
Conditions: Covid19|SARS-CoV Infection
Interventions: PROCEDURE: Auricular neuromodulation|PROCEDURE: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Effects of Patupilone on the Pharmacokinetics of Midazolam and Omeprazole in Patients With Advanced Malignancies
Status: COMPLETED
Conditions: Solid Tumors
Interventions: DRUG: Patupilone and Omeprazole|DRUG: Patupilone + Midalzolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Physiologically Based Cord Clamping To Improve Neonatal Outcomes After Elective Cesarean Delivery
Status: RECRUITING
Conditions: Transient Tachypnea of the Newborn
Interventions: OTHER: Physiological based cord clamping|OTHER: Differed cord clamping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transfusion Requirements in Surgical Oncologic Patient
Status: COMPLETED
Conditions: Red Blood Cells Transfusion|Oncologic Surgery
Interventions: OTHER: Red blood cell transfusion|OTHER: Red blood cell transfusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ex Vivo-activated Autologous Lymph Node Lymphocytes in Treating Patients With Chronic Lymphocytic Leukemia
Status: COMPLETED
Conditions: Anemia|Cancer Fatigue|Chronic Lymphocytic Leukemia|Fever|Infectious Disorder|Lymphadenopathy|Lymphocytosis|Night Sweats|Prolymphocytic Leukemia|Recurrent Chronic Lymphocytic Leukemia|Richter Syndrome|Secondary Malignant Neoplasm|Thrombocytopenia|Weight Loss
Interventions: BIOLOGICAL: Ex Vivo-activated Autologous Lymph Node Lymphocytes|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sucrase-isomaltase Deficiency as a Cause of Irritable Bowel Syndrome
Status: NOT_YET_RECRUITING
Conditions: Irritable Bowel Syndrome|Sucrose Intolerance Due to Sucrase-Isomaltase Deficiency|Carbohydrate; Malabsorption|Sucrase Isomaltase Deficiency|Functional Gastrointestinal Disorders
Interventions: OTHER: Low-FODMAP diet|OTHER: Starch- and Sucrose Reduced Diet (SSRD)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Relative Bioavailability and Food Effect Study
Status: WITHDRAWN
Conditions: Pain
Interventions: DRUG: PH797804|DRUG: PH797804|DRUG: PH797804|DRUG: PH797804
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy of Budesonide-Formoterol in Bronchiectasis
Status: COMPLETED
Conditions: Bronchiectasis
Interventions: DRUG: budesonide-formoterol single inhaler|DRUG: High dose of budesonide|DRUG: A|DRUG: B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Does PAI Reduce Pain After TKA Among Knee Arthroplasty Patients Receiving ACB & IPACK?
Status: COMPLETED
Conditions: Total Knee Athroplasty
Interventions: DRUG: Periarticular Injection (PAI)|DRUG: Saline Control Periarticular Injection (PAI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of the Effectiveness of Nail Genesis DLSO Product for Onychomycosis
Status: RECRUITING
Conditions: Distal Lateral Subungual Onychomycosis|Onychomycosis
Interventions: DEVICE: Nail Genesis DLSO Product|DEVICE: Nail Genesis DLSO Product (vehicle only)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Validity of Aortic Pulse Wave Velocity in Predicting the 6- Minute Walking Test Before Major Non-cardiac Surgery
Status: UNKNOWN
Conditions: Perioperative/Postoperative Complications|Surgery|Exercise Tolerance
Interventions: DIAGNOSTIC_TEST: Aortic pulse wave velocity measurement|DIAGNOSTIC_TEST: 6 minutes walking test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Lenalidomide in Improving Immune Response to Vaccine Therapy in Patients With Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, or Monoclonal B Cell Lymphocytosis
Status: TERMINATED
Conditions: Monoclonal B-Cell Lymphocytosis|Stage 0 Chronic Lymphocytic Leukemia|Stage I Chronic Lymphocytic Leukemia|Stage I Small Lymphocytic Lymphoma
Interventions: OTHER: Laboratory Biomarker Analysis|DRUG: Lenalidomide|BIOLOGICAL: Pneumococcal 13-valent Conjugate Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: FUSION Regimen: Combined Pro re Nata and Fixed Regimen Ranibizumab in Exudative Age-related Macular Degeneration
Status: COMPLETED
Conditions: Exudative Age-related Macular Degeneration
Interventions: DRUG: Ranibizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transfer of Bone Marrow Derived Stem Cells for the Treatment of Spinal Cord Injury
Status: SUSPENDED
Conditions: Spinal Cord Injury
Interventions: BIOLOGICAL: Autologous bone marrow-derived mesenchymal stem cells.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Surface Hardness and Wear Characteristics of Prefabricated and CAD/CAM Milled Artificial Teeth
Status: COMPLETED
Conditions: Surface Hardness and Wear Resistance of Artificial Teeth
Interventions: OTHER: surface hardness test for denture teeth|OTHER: wear resistance of denture teeth measurement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Clinical Study of the Performance of a Glucose Blinding Protein-Based Continuous Glucose Monitor (GBP CGM)
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus
Interventions: DEVICE: GBP CGM
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phase 3 Study to Evaluate the Efficacy and Safety of DW-1030 and Eperisone HCl in Acute Back Pain Patients
Status: COMPLETED
Conditions: Acute Back Pain
Interventions: DRUG: DW-1030(eperisone HCl) 75mg|DRUG: Myonal Tab.(eperisone HCl) 50mg|DRUG: Placebo drug of DW-1030|DRUG: Placebo drug of Myonal Tab.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of Two Different Strategies for Restenosis in Sirolimus-Eluting Stents
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DEVICE: Sirolimus eluting stent|DEVICE: Paclitaxel-eluting stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PO Methadone Ortho Outpatient
Status: NOT_YET_RECRUITING
Conditions: Arthroscopic Knee Repair|Arthroscopic Hip Repair
Interventions: DRUG: Methadone group|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pregnancy Outcome of Women Using Low Molecular Weight Heparin Before Frozen-thawed Embryo Transfer
Status: UNKNOWN
Conditions: Infertility
Interventions: DRUG: estrogen|DRUG: Low Molecular Weight Heparin|DRUG: hCG|DRUG: progesterone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sorafenib and Bevacizumab to Treat Ovarian, Fallopian and Peritoneal Cancer
Status: COMPLETED
Conditions: Ovarian Neoplasm|Fallopian Tube Cancer|Primary Peritoneal Cancer
Interventions: DRUG: Bevacizumab|DRUG: BAY 43-9006
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ph II Letrozole + OSI-774 (Tarceva) in Post-menopausal, w/ ER and/or PR-positive Met Breast Cancer.
Status: TERMINATED
Conditions: Breast Cancer
Interventions: DRUG: erlotinib hydrochloride|DRUG: letrozole|GENETIC: fluorescence in situ hybridization|OTHER: immunohistochemistry staining method|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study To Estimate The Time Course Of PF-04764793 In The Blood Following Dosing By Oral Inhalation From Dry Powder Inhalers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Treatment A|DRUG: Treatment B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Safety of Thrombectomy in Stroke With Extended Lesion and Extended Time Window
Status: TERMINATED
Conditions: Stroke, Acute|Cerebral Stroke|Cerebrovascular Stroke|Apoplexy; Brain
Interventions: DEVICE: Thrombectomy|OTHER: Best medical care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Research Study of ATG and Rituximab in Renal Transplantation
Status: TERMINATED
Conditions: Renal Transplant Recipients
Interventions: DRUG: ATG|DRUG: Rituximab|DRUG: Tacrolimus|DRUG: Sirolimus|DRUG: MMF
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Dietary Palmitic Acid Triacylglyceride Position on Intestinal Parameters in Infants (InFat_005)
Status: COMPLETED
Conditions: Health Behavior|Disorder of Growth and Development
Interventions: OTHER: InFat™ based infant formula|OTHER: Standard vegetable oil based infant formula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Hair Transplantation in Cicatricial Alopecia
Status: COMPLETED
Conditions: Hair Transplantation|Cicatricial Alopecia
Interventions: PROCEDURE: follicular unit extarcation and platelet rich plasma
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Sintilimab in Combination With Carboplatin and Nab-paclitaxel in Resectable Oral Cavity or Oropharyngeal Squamous Cell Carcinoma
Status: RECRUITING
Conditions: Oral Squamous Cell Carcinoma|Oropharyngeal Squamous Cell Carcinoma
Interventions: DRUG: sintilimab, paclitaxel, carboplatin|PROCEDURE: Surgical resection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT