pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Intrathecal Tetanus Immunoglobulin to Treat Tetanus
Status: COMPLETED
Conditions: Tetanus
Interventions: PROCEDURE: Human tetanus immunoglobulin|PROCEDURE: Intramuscular antitoxin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: AB-2004 in Treatment of Irritability Associated With Autism Spectrum Disorder (ASD)
Status: ACTIVE_NOT_RECRUITING
Conditions: Autism Spectrum Disorder (ASD)
Interventions: DRUG: AB-2004|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pulsed Electromagnetic Field Treatment In Patients With Alzheimer's Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Alzheimer Disease
Interventions: DEVICE: ECHS AD Device|DEVICE: ECHS Sham AD Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized, Placebo-controlled Study Comparing Efficacy of Fluticasone/Salmeterol Combination to Advair in Asthmatics
Status: WITHDRAWN
Conditions: Asthma
Interventions: DRUG: Fluticasone propionate 100 mcg / salmeterol 50 mcg|DRUG: Generic fluticasone propionate 100 mcg / salmeterol 50 mcg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment and Management of Women With Bleeding Disorders
Status: COMPLETED
Conditions: Menorrhagia|Blood Coagulation Disorders|Blood Platelet Disorders|Von Willebrand Disease|Hematologic Disease
Interventions: DRUG: Tranexamic Acid|DRUG: Desmopressin Acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy of Endocuff-assisted Colonoscopy for Adenoma Detection.
Status: COMPLETED
Conditions: Adenomatous Polyps
Interventions: DEVICE: EndoCuff-assisted colonoscopy|DEVICE: Standard Colonoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Vibrational Therapy to Improve Gait and Balance in Parkinson's Disease
Status: WITHDRAWN
Conditions: Parkinson Disease
Interventions: DEVICE: PDVibe2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Knee Kinematics for Subjects With Zimmer-Biomet Posterior Cruciate Retaining or Posterior Stabilizing Total Knee Arthroplasty
Status: COMPLETED
Conditions: Arthroplasty, Replacement, Knee|Osteoarthritis, Knee
Interventions: DEVICE: Zimmer-Biomet Posterior Cruciate Retaining total knee arthroplasty|DEVICE: Zimmer-Biomet Posterior Stabilizing total knee arthroplasty
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: SAD/MAD of ABX-002-1902 Investigating the Safety, Pharmacokinetics/Pharmacodynamics of in Healthy Subjects
Status: COMPLETED
Conditions: MDD
Interventions: DRUG: ABX-002|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pain Perception and Wound Healing After Laser-assisted Frenectomy in Children
Status: COMPLETED
Conditions: Frenulum; Hypertrophy
Interventions: DEVICE: Laser-assisted frenectomy with 2780 nm Er:Cr;YSGG and 940 nm diode laser
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A 6-Month Study to Evaluate the Safety & Potential Efficacy of Trappsol Cyclo in Patients With Early Alzheimer's Disease
Status: RECRUITING
Conditions: Alzheimer's Disease
Interventions: DRUG: Hydroxypropyl Beta Cyclodextrin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Effects of a Synbiotic Versus Probiotic or Placebo on Gut Microbiota and Cardiometabolic Health: A Randomized Double-Blind Placebo Controlled Trial
Status: RECRUITING
Conditions: Blood Pressure, Body Composition, Immune Function
Interventions: DIETARY_SUPPLEMENT: Synbiotic, Probiotic, Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of Parsaclisib, a PI3Kδ Inhibitor, in Combination With Bendamustine and Rituximab in Patients With Newly Diagnosed Mantle Cell Lymphoma
Status: WITHDRAWN
Conditions: Mantle Cell Lymphoma
Interventions: DRUG: parsaclisib|DRUG: rituximab|DRUG: bendamustine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Raltegravir-based Antiretroviral Versus Maintaining Any Other Antiretroviral Therapy in HIV Mono-infected Patients
Status: COMPLETED
Conditions: HIV|Fatty Liver|Nonalcoholic Steatohepatitis
Interventions: DRUG: Isentress.|OTHER: Continue usual antiretroviral therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Effect of Vitamin D on Skeletal Muscle Function and Qol in Patients With Chronic Intestinal Failure/Insufficiency
Status: RECRUITING
Conditions: Intestinal Failure
Interventions: DRUG: Vitamin D
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intraoperative Dialysis in Liver Transplantation
Status: TERMINATED
Conditions: Liver Failure|Acute Kidney Disease|Multi-organ Failure
Interventions: DEVICE: Continuous renal replacement therapy (CRRT)|PROCEDURE: Standard intraoperative support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The High-Dose Aldesleukin (IL-2) "Select" Trial for Patients With Metastatic Renal Cell Carcinoma
Status: COMPLETED
Conditions: Metastatic Renal Cell Carcinoma
Interventions: DRUG: HD IL2
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Urinary and Prostate Microbiotes and Prostate Cancer
Status: COMPLETED
Conditions: Prostatic Neoplasm
Interventions: PROCEDURE: prostate biopsy|OTHER: Urinary sampling|OTHER: Rectal swabbing before biopsies are performed
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety and Efficacy Study of Betamarc to Treat Loss of Weight and Appetite in Non-Small Cell Lung Cancer
Status: TERMINATED
Conditions: Anorexia|Cachexia|Weight Loss|Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: Betamarc
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Melanated Group Midwifery Care (MGMC)
Status: RECRUITING
Conditions: Pregnancy Complications|Maternal Care Patterns|Patient Engagement
Interventions: BEHAVIORAL: Melanated Group Midwifery Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Use of Artificial Intelligence for Clinical Assessment of Assisted Reproductive Techniques and IVF Outcomes
Status: ACTIVE_NOT_RECRUITING
Conditions: Infertility|in Vitro Fertilization (IVF)|ART
Interventions: OTHER: AI to analyze 3 D ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Antioxidants Combined With Cryotherapy on Inflammatory Response After Resistance Exercise in Untrained Volunteers
Status: COMPLETED
Conditions: Inflammation|Oxidative Stress|Pain
Interventions: OTHER: Cryotherapy|OTHER: Vitamins C and E|OTHER: Vitamins C and E associated with cryotherapy|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Darbe Administration in Newborns Undergoing Cooling for Encephalopathy
Status: COMPLETED
Conditions: Hypoxic Ischemic Encephalopathy
Interventions: DRUG: Darbepoetin alfa|DRUG: Darbepoetin alfa|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: High Tone Power Therapy Versus Interferential Current Therapy in Mothers With Breastfeeding-Related Neck Pain
Status: RECRUITING
Conditions: Breastfeeding
Interventions: DEVICE: high tone power therapy|DEVICE: interferential current therapy|DEVICE: conventional physical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Laparoscopic Versus Robot-assisted Ventral Hernia Repair: a Single Institution Randomized Controlled Trial
Status: WITHDRAWN
Conditions: Ventral Hernia
Interventions: PROCEDURE: laparoscopic repair|PROCEDURE: robot-assisted repair
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non-alcoholic Fatty Liver Disease (NAFLD) in HIV: The Role of Nutritional Interventions
Status: TERMINATED
Conditions: HIV Infections|Fatty Liver
Interventions: DRUG: antioxidant vitamin E|BEHAVIORAL: weight reduction and exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prehospital Non-invasive Cooling of Comatose Patients After Cardiac Arrest
Status: WITHDRAWN
Conditions: Cardiac Arrest|Postresuscitation Encephalopathy
Interventions: DEVICE: CAERVest cooling device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Homeopathic Oral Antibodies to Treat Viral Upper Respiratory Tract Infections
Status: COMPLETED
Conditions: Common Cold
Interventions: DRUG: TAO1, oral homeopathic antibodies
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Development and Validation of a Deep Learning-based Myopia and Myopic Maculopathy Detection and Prediction System
Status: COMPLETED
Conditions: Myopia|Myopic Macular Degeneration
Interventions: DIAGNOSTIC_TEST: A deep learning-based myopia and myopic maculopathy detection and prediction system
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Capecitabine, Cetuximab, Oxaliplatin, and Bevacizumab in Treating Patients With Metastatic or Recurrent Colorectal Cancer That Cannot Be Removed By Surgery
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: BIOLOGICAL: bevacizumab|BIOLOGICAL: cetuximab|DRUG: capecitabine|DRUG: oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of F520 Combined With Lenvatinib in the Treatment of Patients With Advanced Solid Tumors
Status: RECRUITING
Conditions: Solid Tumors
Interventions: DRUG: F520|DRUG: Lenvatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 7T Amygdala and Citalopram Study
Status: NOT_YET_RECRUITING
Conditions: Emotional Processing|Cognition|Mood Disorders|Depressive Disorder|Depression
Interventions: DRUG: Citalopram|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Long-Term Follow-up Safety Study of Human Central Nervous System Stem Cells in Subjects With Geographic Atrophy of Age-Related Macular Degeneration
Status: TERMINATED
Conditions: Age-Related Macular Degeneration|Geographic Atrophy
Interventions: BIOLOGICAL: Human Central Nervous System Stem Cells
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluating Impacts of CSS for Veterans and Their Families in Ukraine
Status: COMPLETED
Conditions: Psychosocial Problem|Psychological Distress|Engagement, Patient
Interventions: BEHAVIORAL: CETA Short Session (CSS)|BEHAVIORAL: Psychoeducation and Safety
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: IVIG and Rituximab in Antibody-associated Psychosis - SINAPPS2
Status: RECRUITING
Conditions: Psychosis|Autoimmune Encephalitis
Interventions: DRUG: Intravenous immunoglobulin|DRUG: Placebo|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Spinal Fusion and Rehabilitation Study
Status: COMPLETED
Conditions: Spondylolisthesis, Degenerative|Spondylolisthesis, Isthmic
Interventions: OTHER: Outcome of lumbar spinal fusion patients and significance of postoperative exercise therapy: A randomized controlled trial
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: The Importance of Different Implant Surfaces of the Tibial Component for Migration and Adaptive Bone Remodeling in Uncemented Total Knee Arthroplasty (Vanguard Versus Regenerex)
Status: COMPLETED
Conditions: Artrosis of the Knee
Interventions: DEVICE: Vanguard|DEVICE: Regenerex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: pBFS-guided iTBS Over the Left DLPFC for Chronic PSCI
Status: RECRUITING
Conditions: Chronic Stroke|Cognitive Impairment
Interventions: DEVICE: active iTBS|DEVICE: sham iTBS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: McGill Stabilization Exercises VS Proprioceptive Neuromuscular Facilitation Technique in Chronic Non-specific LBP
Status: COMPLETED
Conditions: Chronic Non-specific Low Back Pain
Interventions: OTHER: McGill stabilization exercise|OTHER: Proprioceptive neuromuscular facilitation technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Percutaneous Neuromuscular Electrical Stimulation in Patients With Chronic Low Back Pain
Status: RECRUITING
Conditions: Low Back Pain
Interventions: OTHER: Percutaneous neuromuscular electrical stimulation (PNMES) plus motor control exercise program|OTHER: Sham PNMES (introducing the needle) plus motor control exercise program|OTHER: TENS plus motor control exercise program|OTHER: Sham PNMES (without inserting the needle) plus motor control exercise program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I Dasatinib/Erlotinib in Recurrent Non-small Cell Lung Cancer (NSCLC)
Status: COMPLETED
Conditions: Non-Small-Cell Lung Carcinoma
Interventions: DRUG: Erlotinib in combination with Dasatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Carboplatin Chemotherapy Before Surgery for People With High-Risk Prostate Cancer and an Inherited BRCA1 or BRCA2 Gene Mutation
Status: RECRUITING
Conditions: Prostate Adenocarcinoma|Stage IIIB Prostate Cancer AJCC v8|Stage IIIC Prostate Cancer AJCC v8
Interventions: PROCEDURE: Biospecimen Collection|DRUG: Carboplatin|PROCEDURE: Chest Radiography|PROCEDURE: Computed Tomography|PROCEDURE: Magnetic Resonance Imaging|PROCEDURE: PSMA PET Scan|PROCEDURE: Surgical Procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Compression Glove to Prevent Complications After Distal Radius Fractures: a Randomized Controlled Trial
Status: TERMINATED
Conditions: Post-traumatic Carpal Tunnel Syndrome|Complex Regional Pain Syndrome|Edema
Interventions: DEVICE: Compression glove
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Performance Study of an Artificial Nerve Guide (Reaxon® Nerve Guide) to Treat Digital Nerve Lesions
Status: TERMINATED
Conditions: Peripheral Nerve Injuries
Interventions: DEVICE: Implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Comparing Pulmonary Vein Isolation With the Cryoballoon, Radiofrequency Energy, or Both in the Treatment of Atrial Fibrillation (AF)
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: PROCEDURE: Atrial fibrillation ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Rhythmic Balance Auditory Vision Training And Strength Training With Autism Spectrum Disorder.
Status: RECRUITING
Conditions: Autism Spectrum Disorder
Interventions: OTHER: Rhythmic balance visual auditory exercise + Routine physical therapy|OTHER: Strength Training + Routine Physical Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Augmentation of Brief Habit Reversal Training With D-cycloserine or Placebo
Status: COMPLETED
Conditions: Tourette Disorder|Chronic Tic Disorder
Interventions: DRUG: D-cycloserine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mirror Therapy Versus Task Oriented Training on Hand Function in Children With Unilateral Cerebral Palsy
Status: NOT_YET_RECRUITING
Conditions: Unilateral Cerebral Palsy
Interventions: OTHER: Selected Physical and Occupational Therapy Program|OTHER: Mirror Therapy|OTHER: Task-Oriented Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fruquintinib Sequential BEV+FOLFIRI vs. BEV+FOLFIRI Sequential Fruquintinib in Metastatic Colorectal Cancer
Status: NOT_YET_RECRUITING
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: Fruquintinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Paracervical Block Versus No Paracervical Block During IUD Insertion
Status: COMPLETED
Conditions: Analgesia|IUD Insertion
Interventions: DRUG: Lidocaine|OTHER: No analgesia|DEVICE: Intrauterine device (IUD)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trastuzumab Deruxtecan (T-DXd) With or Without Pertuzumab Versus Taxane, Trastuzumab and Pertuzumab in HER2-positive Metastatic Breast Cancer (DESTINY-Breast09)
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer; HER2-positive; Metastatic
Interventions: DRUG: Trastuzumab deruxtecan|DRUG: Placebo|DRUG: Taxane|DRUG: Pertuzumab|DRUG: Trastuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Pathway With "Fast-Track" In Uncomplicated Acute Appendicitis
Status: UNKNOWN
Conditions: Uncomplicated Acute Appendicitis
Interventions: OTHER: Clinical Pathway with "Fast-Track"|OTHER: Postoperative Usual Protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Life-Steps Counseling to Enhance Adherence and Engagement in PrEP Care
Status: ACTIVE_NOT_RECRUITING
Conditions: Adherence, Medication
Interventions: BEHAVIORAL: Lifesteps for PrEP|BEHAVIORAL: Daily text message reminders
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: SHR-1210 Combined With Apatinib Mesylate in the Perioperative Therapy for Hepatocellular Carcinoma
Status: RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Apatinib Mesylate|DRUG: Camrelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral Chemotherapeutic Drugs Were Analyzed in Patients With Driver Gene Negative Locally Advanced/Advanced Non-small Cell Lung Cancer With PS Score 2 A Prospective, Single-arm, Multicenter, Observational Study on the Efficacy and Safety of Radiochemotherapy Combined With PD-1 Inhibitor
Status: RECRUITING
Conditions: Non-small Cell Lung Cancer Stage IIIB/IV
Interventions: DRUG: Navelbine oral,Pembrolizumab
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Balloon Dilation of the Eustachian Tube in Children
Status: UNKNOWN
Conditions: Glue Ear|Tube Disorders Eustachian
Interventions: PROCEDURE: Balloon Eustachian Tuboplasty (BET)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Computerized PAINRelieveIt Protocol for Cancer Pain Control in Hospice
Status: UNKNOWN
Conditions: Cancer|Pain
Interventions: BEHAVIORAL: PAINReportIt|BEHAVIORAL: PAINConsultN|BEHAVIORAL: PAINUCope
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: SATIN WP4 Acute Effect on Appetite of Pineapple Juice With Viscofiber and Red Ginseng
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: SATIN pineapple|DIETARY_SUPPLEMENT: SATIN pineapple control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study for the Treatment of Ocular Chronic Graft-Versus-Host Disease (GVHD) With Amniotic Fluid Eye Drops (AFED)
Status: COMPLETED
Conditions: Ocular Graft Versus Host Disease
Interventions: BIOLOGICAL: Amniotic Fluid Eye Drops (AFED)|OTHER: Saline Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Safety, Efficacy, and Tolerability of Microbial Ecosystem Therapeutic-2 in People With Major Depression
Status: UNKNOWN
Conditions: Major Depressive Disorder|Anxiety
Interventions: DRUG: MET-2|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Analgesic Efficacy of Local Anaesthetic Wound Infiltration Versus Intrathecal Morphine for Total Knee Replacement
Status: UNKNOWN
Conditions: Total Knee Replacement
Interventions: DRUG: Levobupivacaine|DRUG: Intrathecal morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Acetated Ringer´s Solution in Experimental Hypovolemia
Status: RECRUITING
Conditions: Hypovolemia|Fluid Loss|Hemodynamic Instability
Interventions: DRUG: Ringer acetate|OTHER: Lower body negative pressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Expanded Game Squad for Neurodiverse Youth
Status: COMPLETED
Conditions: Physical Activity|Mental Health Issue (E.G., Depression, Psychosis, Personality Disorder, Substance Abuse)|Health Behavior|Developmental Disorder
Interventions: BEHAVIORAL: NDGameSquad
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of Faster-acting Insulin Aspart Compared to NovoRapid® Both in Combination With Insulin Degludec in Children and Adolescents With Type 1 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 1
Interventions: DRUG: Faster-acting insulin aspart|DRUG: insulin aspart|DRUG: insulin degludec
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: NHL16: Study For Newly Diagnosed Patients With Acute Lymphoblastic Lymphoma
Status: COMPLETED
Conditions: Lymphoblastic Lymphoma
Interventions: DRUG: Prednisone|DRUG: Vincristine|DRUG: Daunorubicin|DRUG: PEG-asparaginase|DRUG: Erwinia asparaginase|DRUG: Doxorubicin|DRUG: Cyclophosphamide|DRUG: Cytarabine|DRUG: Thioguanine|DRUG: Clofarabine|DRUG: Methotrexate|DRUG: Mercaptopurine|DRUG: Dexamethasone|DRUG: Hydrocortisone|DRUG: Etoposide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The RepEAT Study: Individual Differences in Postprandial Glucose Responses and the Relation With Diet and Phenotype
Status: COMPLETED
Conditions: Postprandial Glucose Responses|Glucose Metabolism
Interventions: OTHER: Standardized diet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluation Of Peripheral Muscle Oxygenation In Individuals With Muscular Idiopathic Pain With Myofascial Release
Status: COMPLETED
Conditions: Trapezius Muscle Strain
Interventions: OTHER: Myofascial Release|OTHER: Continuous Surface Slip Technique|OTHER: Without intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Metformin and Esomeprazole in Preterm Pre-eclampsia
Status: ACTIVE_NOT_RECRUITING
Conditions: Preeclampsia Severe|Pre-Eclampsia|Preeclampsia|Preeclampsia Second Trimester|Preeclampsia Complicating Childbirth|Preeclampsia Puerperium|Preterm
Interventions: DRUG: Metformin|DRUG: Esomeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Peripheral Modulation of Muscle Stiffness and Spasticity
Status: RECRUITING
Conditions: Muscle Spasticity
Interventions: DRUG: Hyaluronidase|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Platelet-rich Plasma in Symptomatic Knee Osteoarthritis
Status: NOT_YET_RECRUITING
Conditions: Knee Osteoarthritis
Interventions: PROCEDURE: PRP injection|PROCEDURE: Placebo injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lenalidomide With or Without Dexamethasone in Treating Patients With Newly Diagnosed Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma and Plasma Cell Neoplasm
Interventions: DRUG: dexamethasone|DRUG: lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: LIthium as Bridging thErapy Prior to Radioactiveiodine in hyperThYroidism
Status: COMPLETED
Conditions: Hyperthyroidism/Thyrotoxicosis
Interventions: PROCEDURE: radioactive iodine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aspirin for the Enhancement of Trophoblastic Invasion in Women With Abnormal Uterine Artery Doppler at 11-14 Weeks of Gestation
Status: COMPLETED
Conditions: Placental Insufficiency
Interventions: DRUG: Aspirin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Induction Chemotherapy Followed By Chrono-chemotherapy Concurrent With IMRT Of Locally Advanced NPC Clinical Study
Status: UNKNOWN
Conditions: Nasopharyngeal Carcinoma
Interventions: DEVICE: Chrono-chemotherapy pump:Melodie|DEVICE: Routine intravenous drip|DRUG: induction chemotherapy|DRUG: cisplatin chrono-chemotherapy|RADIATION: intensity-modulated radiation therapy|DRUG: cisplatin routine-chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Accuracy and Stability of a New Automatic Knee Arthrometer in Diagnosing ACL Rupture
Status: COMPLETED
Conditions: Knee Ligament; Laxity
Interventions: DIAGNOSTIC_TEST: Side-to-side difference (reproducibility)|DIAGNOSTIC_TEST: Side-to-side difference (availability)|DIAGNOSTIC_TEST: Side-to-side difference (Accuracy)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Itraconazole and Rifampin on the Blood Tazemetostat Levels
Status: COMPLETED
Conditions: All Malignancies|Advanced Malignancies|Hematologic Malignancy|Solid Tumor|Follicular Lymphoma (FL)|Non-Hodgkin Lymphoma (NHL)|Diffuse Large B-Cell Lymphoma (DLBCL)|Epithelioid Sarcoma (ES)|Synovial Sarcoma|Renal Medullary Carcinoma|Mesothelioma|Rhabdoid Tumor
Interventions: DRUG: Tazemetostat|DRUG: Itraconazole|DRUG: Tazemetostat|DRUG: Rifampin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Construal Level as a Novel Pathway for Affect Regulation and Cancer Control
Status: RECRUITING
Conditions: Smoking Cessation|Smoking Reduction|Cancer
Interventions: BEHAVIORAL: High-level construal|BEHAVIORAL: Down-regulation of craving for cigarettes|BEHAVIORAL: Up-regulation of goal energization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Hepatitis C Treatment in PWIDs: MAT or Syringe Exchange Assisted-therapy vs Standard of Care
Status: COMPLETED
Conditions: Hepatitis C|Substance Use Disorders|Substance Abuse, Intravenous
Interventions: DRUG: elbasvir-grazoprevir (50 mg/100 mg)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Drug Treatment for Cocaine Users Who Are Also on Methadone Maintenance Treatment
Status: TERMINATED
Conditions: Cocaine Dependence|Opiate Dependence
Interventions: DRUG: Atomoxetine, low dose|DRUG: Atomoxetine, high dose|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Telehealth Education in Diabetes Patients
Status: NOT_YET_RECRUITING
Conditions: Diabetes Mellitus, Type 1|Diabetes Mellitus, Type 2
Interventions: BEHAVIORAL: Standard education|BEHAVIORAL: Ampiled Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Bortezomib and Bevacizumab ("BB-mib-mab") in Patients With Advanced or Recurrent Renal Cell Cancer (RCC)
Status: UNKNOWN
Conditions: Renal Cell Cancer
Interventions: DRUG: Bevacizumab and Bortezomib|DRUG: Bevacizumab and Bortezomib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Cognitive Processing Therapy (CPT) Versus Present Centered Therapy (PCT) for Veterans
Status: COMPLETED
Conditions: PTSD
Interventions: BEHAVIORAL: Cognitive Processing Therapy|BEHAVIORAL: Present Centered Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Music After Stroke To Enhance Rehabilitation
Status: UNKNOWN
Conditions: Stroke, Acute|Expressive Aphasia|Movement, Abnormal|Depressive Disorder
Interventions: DEVICE: Ipod with music|DEVICE: ipod with books to listen|DEVICE: ipod only with usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess Safety, Tolerability and Pharmacokinetics After Single Doses of AZD2516 to Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: AZD2516|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Stanford Accelerated Intelligent Neuromodulation Therapy for Treatment-Resistant Depression (SAINT-TRD)
Status: COMPLETED
Conditions: Treatment Resistant Depression
Interventions: DEVICE: Active TBS-DLPFC|DEVICE: Sham TBS-DLPFC|DEVICE: Open label TBS-DLPFC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Extension to a Study on the Efficacy and Safety of Vildagliptin in Combination With Metformin in Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: vildagliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Study To Assess the Quality and Strength of Bone in Women Participants With Osteoporosis Taking Oral Ibandronate Versus Placebo
Status: COMPLETED
Conditions: Osteoporosis
Interventions: DRUG: ibandronate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Venetoclax in Combination With Decitabine in Subjects With Acute Myeloid Leukemia
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Decitabine|DRUG: Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Novel Gentic Variations Contributing to Asthma Susceptability in Saudi Arabia
Status: COMPLETED
Conditions: Collection of Clinical Data That Will be Used in This Study and Will Form a Data Bank for Asthma in Saudi Arabia|Identify Known and NOVEL Genetic Risk Factors Contributing to Asthma Susceptibility|Study the Mechanistic Roles of the Genetic Variants Within Major Asthma Susceptibility Genes
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Influence of Calcium Hydroxide Chlorhexidine Combination vs. Calcium Hydroxide as an Intra Canal Medicaments in Retreatment Cases
Status: UNKNOWN
Conditions: Postoperative Flare up
Interventions: DRUG: combination of calcium hydroxide and chlorhexidine|DRUG: Calcium Hydroxide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Azilsartan Medoxomil in Participants With Mild to Moderate Hypertension
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Azilsartan Medoxomil|DRUG: Azilsartan Medoxomil|DRUG: Azilsartan Medoxomil|DRUG: Azilsartan Medoxomil|DRUG: Azilsartan Medoxomil|DRUG: Olmesartan|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of a Therapeutic Vaccine With NY-ESO-1 in Combination With the Adjuvant Monophosphoryl Lipid A (MPLA)
Status: UNKNOWN
Conditions: Cancer.|Melanoma.|Ovarian Cancer.|Lung Cancer.
Interventions: BIOLOGICAL: NY-ESO-1 combined with MPLA|BIOLOGICAL: NY-ESO-1 combined with MPLA vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Project QueST 2023: Queer Survivors of Trauma
Status: ACTIVE_NOT_RECRUITING
Conditions: Stress Disorders, Post-Traumatic|Drinking Heavy
Interventions: BEHAVIORAL: Trauma Expressive Writing|BEHAVIORAL: Stigma Expressive Writing|BEHAVIORAL: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: AZD6765 Single and Multiple Ascending Dose Study in Healthy Male and Female Japanese and Caucasian Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: AZD6765|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Pharmacokinetics of AM1476 in Healthy Subjects
Status: COMPLETED
Conditions: Safety|Tolerability
Interventions: DRUG: AM1476|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vasopressin Versus Epinephrine in Myomectomy
Status: COMPLETED
Conditions: Uterine Myomas
Interventions: DRUG: Epinephrine|DRUG: Vasopressin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Potential Benefit of Xiao-Yao-San Treatment in Patients With Insomnia
Status: COMPLETED
Conditions: Insomnia, Chinese Herbs, Xiao-Yao-San, Polysomnography
Interventions: DRUG: Xiao Yao San|OTHER: Weight loss class(WLC) group
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Robotic-assisted Gait Training Combined With Transcranial Direct Current Stimulation to Maximize Gait Recovery After Stroke
Status: COMPLETED
Conditions: Stroke
Interventions: DEVICE: tDCS|DEVICE: Robotic-assisted gait training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of a Personalized Neoantigen Cancer Vaccine in Treating Patients With Advanced Malignant Tumor
Status: UNKNOWN
Conditions: Advanced Malignant Solid Tumor
Interventions: BIOLOGICAL: iNeo-Vac-P01|OTHER: GM-CSF
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Evaluate the Efficacy of Ectoin® Containing Eye Spray for Treatment of Dry Eye Disease
Status: COMPLETED
Conditions: Dry Eye
Interventions: DEVICE: Ectoin® Eye Spray - Colloidal|DEVICE: Liposomal eye spray Tears Again®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of rATG Individualized Administration in Haploidentical Hematopoietic Stem Cell Transplantation
Status: RECRUITING
Conditions: Hematopoietic Stem Cell Transplantation|Acute Leukemia
Interventions: DRUG: Individual ATG|DRUG: ATG
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Can Correction of Low Vitamin D Status in Infancy Program for a Leaner Body Composition?
Status: TERMINATED
Conditions: Healthy|Vitamin D Deficiency|Gestational Diabetes
Interventions: DIETARY_SUPPLEMENT: cholecalciferol|DIETARY_SUPPLEMENT: Reference 400
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effect of Multiple Doses of CC-90001 on the Pharmacokinetics of Omeprazole, Midazolam, Warfarin, Rosuvastatin, Metformin, Digoxin, and Nintedanib in Healthy Adult Subjects
Status: COMPLETED
Conditions: Heathy Volunteer
Interventions: DRUG: CC-90001|DRUG: Omeprazole|DRUG: Midazolam|DRUG: Warfarin|DIETARY_SUPPLEMENT: Vitamin K|DRUG: Rosuvastatin|DRUG: Metformin|DRUG: Digoxin|DRUG: Nintedanib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I Interaction Study of Istaroxime and Digoxin in Subjects With Stable Heart Failure
Status: WITHDRAWN
Conditions: Heart Failure
Interventions: DRUG: Istaroxime|DRUG: Istaroxime|DRUG: Istaroxime|DRUG: Istaroxime
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect on Energy Metabolism at Cellular Level of Diet Plus Treatment With Ephedrine and Caffeine in Obesity
Status: COMPLETED
Conditions: Obesity
Interventions: DRUG: Caffeine|DRUG: Placebo|DRUG: Ephedrine|OTHER: Hypocaloric diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Small-molecule Carbonic Anhydrase IX Targeting PET Tracer in Clear Cell Renal Cell Carcinoma
Status: COMPLETED
Conditions: Clear Cell Renal Cell Carcinoma
Interventions: DRUG: 68Ga-NY104
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of ECHELON 3000 (Next Generation Powered Stapler) in General Abdominal and Thoracic Lung Resection Procedures
Status: RECRUITING
Conditions: Laparoscopic Sleeve Gastrectomy (LSG)|Thoracic Lung Resection Procedure
Interventions: DEVICE: ECHELON 3000 Stapler
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparative Effectiveness of FIT, Colonoscopy, & Usual Care Screening Strategies
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: OTHER: FIT Screening Strategy|OTHER: Colon Screening Strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Comparison of Two Lower Limb Bypass Types : Prosthesis Versus Autologous Vein
Status: COMPLETED
Conditions: Arteritis|Diabetes
Interventions: DEVICE: femoropopliteal artery bypass|DEVICE: femoropopliteal artery bypass
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of Local Anesthetic Dose on Interscalene Block
Status: COMPLETED
Conditions: Shoulder Arthroscopy|Interscalene Block
Interventions: PROCEDURE: Low Dose (20 ml) Local Anesthetic Volume for Interscalene Block|PROCEDURE: Control Dose (40 mL) Local Anesthetic Volume for Interscalene Block|DRUG: Low Dose (20 mL) Local Anesthetic (Mepivacaine:Bupivacaine)|DRUG: Control Dose (40 mL) Local Anesthetic (Mepivacaine:Bupivacaine)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Insulin Glargine [rDNA Origin] Injection vs Pioglitazone as add-on Therapy in Patients Failing Monotherapy With Sulfonylurea or Metformin
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: insulin glargine [rDNA origin] injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CSD231005 Nicotine Pouch Biomarkers of Exposure
Status: NOT_YET_RECRUITING
Conditions: Tobacco Use|Smoking
Interventions: OTHER: Nicotine Pouch P1312914, 4 mg nicotine|OTHER: Nicotine Pouch P1312915, 8 mg nicotine|OTHER: Nicotine Pouch P1013215, 8 mg nicotine|OTHER: Nicotine Pouch P1013218, 10 mg nicotine|OTHER: Nicotine Pouch P1012919, 12 mg nicotine|OTHER: Smoking Abstinence|OTHER: Continued UB cigarette smoking
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Starch or Saline After Cardiac Surgery
Status: TERMINATED
Conditions: Coronary Artery Bypass Surgery
Interventions: DRUG: 6% Hydroxyethyl Starch 130/0.4|DRUG: 0.9% Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nonivamide/Nicoboxil Ointment in Acute Low Back Pain
Status: COMPLETED
Conditions: Acute Low Back Pain
Interventions: DRUG: nicoboxil|DRUG: placebo matching nonivamide + nicoboxil|DRUG: nonivamide + nicoboxil (Finalgon)|DRUG: nonivamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Effect of Esketamine on Reducing Postoperative Anxiety and Depression in Adolescent Patients
Status: NOT_YET_RECRUITING
Conditions: Anxiety-depression
Interventions: DRUG: Esketamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION