pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Colchicine as Treatment for People With Hand Osteoarthritis
Status: COMPLETED
Conditions: Osteoarthritis Hand|Osteoarthritis Finger
Interventions: DRUG: Colchicine 0.5 MG|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Squalamine for the Treatment in Proliferative Diabetic Retinopathy
Status: COMPLETED
Conditions: Retinal Neovascularization
Interventions: DRUG: Squalamine Lactate ophthalmic solution 0.2%
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: First-in-Human Study of PF-04958242 in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: PF-04958242|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Efficacy of CellCept (Mycophenolate Mofetil) in Patients With Lupus Nephritis
Status: TERMINATED
Conditions: Lupus Nephritis
Interventions: DRUG: Mycophenolate mofetil (MMF)|DRUG: Cyclophosphamide, Maintenance Phase|DRUG: Cyclophosphamide, Induction Phase|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Curcumin for Prevention of Oral Mucositis in Children Chemotherapy
Status: COMPLETED
Conditions: Chemotherapy Induced Mucositis
Interventions: OTHER: Mouth wash|DIETARY_SUPPLEMENT: Curcumol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing Effect of Autologous Platelet-Rich Plasma Versus Hyaluronic Acid Treatment on Knee Osteoarthritis
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: COMBINATION_PRODUCT: Platelet Rich Plasma|COMBINATION_PRODUCT: Hyaluronic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Secretin Enhanced MRCP for Evaluation of Pancreatic Duct in Pediatric Population
Status: TERMINATED
Conditions: Acute Recurrent Pancreatitis|Chronic Pancreatitis
Interventions: DRUG: RG1068 (Synthetic Human Secretin)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Statin Treatment for UnruptureD Intracranial anEurysms Study
Status: UNKNOWN
Conditions: Intracranial Aneurysm|Inflammation Vascular
Interventions: DRUG: Atorvastatin|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Efficacy and Safety of Flumatinib Combined With Chemotherapy in Ph Positive ALL
Status: UNKNOWN
Conditions: Acute Lymphocytic Leukemia, Adult B-Cell|BCR-ABL1 Fusion Protein Expression
Interventions: DRUG: Flumatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Safety and Immunogenicity of PXVX0317 Chikungunya Virus Virus-Like Particle Vaccine
Status: COMPLETED
Conditions: Chikungunya Virus
Interventions: BIOLOGICAL: CHIKV VLP, adjuvanted
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Improving Nighttime Access to Care and Treatment; Part 2- Ghana
Status: RECRUITING
Conditions: Pediatric ALL|Acute Disease
Interventions: OTHER: MotoMeds pediatric telemedicine and medication delivery service (TMDS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Comparison of Hematocrit Levels in Infant Heart Surgery
Status: COMPLETED
Conditions: Cardiovascular Diseases|Heart Diseases|Heart Defects, Congenital|Transposition of Great Vessels
Interventions: PROCEDURE: Cardiopulmonary Bypass with Two Different Intra-Operative Hematocrits|PROCEDURE: Thoracic Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: Ultrasound-guided Femoral Puncture to Reduce Access- Related Complications After TAVR: (ACCESS-TAVR SIRIO)
Status: RECRUITING
Conditions: Transcatheter Aortic Valve Replacement
Interventions: PROCEDURE: US-guided femoral puncture vs Fluoroscopy-guided puncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GeoScan and Remote Geo Smoking Study: Neural and Behavioral Correlates of Smokers' Exposure to Retail Environments
Status: ACTIVE_NOT_RECRUITING
Conditions: Smoking, Tobacco|Smoking|Smoking, Cigarette
Interventions: BEHAVIORAL: 7-11|BEHAVIORAL: CVS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Efficacy/Safety of Frontline Alemtuzumab (Campath, MabCampath) vs Chlorambucil in Patients With Progressive B-Cell Lymphocytic Leukemia
Status: COMPLETED
Conditions: B Cell Chronic Lymphocytic Leukemia
Interventions: DRUG: alemtuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Calcium Reduction by Orbital Atherectomy in Western Europe
Status: RECRUITING
Conditions: Vascular Calcification* / Diagnostic Imaging|Atherectomies, Coronary|Tomography, Optical Coherence|Coronary Intervention, Percutaneous|Coronary Angiography|Humans|Treatment Outcome|Vascular Calcification* / Therapy|Vascular Calcification
Interventions: DEVICE: Orbital Atherectomy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical Trial of Microneedle Radiofrequency Combined With Oral Isotretinoin in Moderate to Severe Acne
Status: RECRUITING
Conditions: Moderate to Severe Acne Vulgaris
Interventions: DRUG: Oral isotretinoin|OTHER: Oral isotretinoin combined with microneedle radiofrequency therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Adalimumab in Combination With Ciprofloxacin/Placebo Treatment of Perianal Fistulas in Crohn's
Status: COMPLETED
Conditions: Crohn's Disease With Perianal Fistulas
Interventions: DRUG: adalimumab|DRUG: ciprofloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dual Endpoint Nerve Stimulation Versus Ultrasound in Infraclavicular Block for Hand Surgery
Status: COMPLETED
Conditions: Hand Surgery
Interventions: PROCEDURE: Ultrasound Guided Infraclavicular Nerve Block|PROCEDURE: Dual-Endpoint nerve stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study the Safety and Effectiveness of Tadalafil in Men With Diabetes Who Have Problems Getting and Keeping an Erection
Status: COMPLETED
Conditions: Impotence
Interventions: DRUG: tadalafil|DRUG: tadalafil|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Bandage Contact Lens and Pressure Patching for The Erosion Area and Pain Scale in Corneal Erosion Patients
Status: COMPLETED
Conditions: Erosion; Cornea, Traumatic
Interventions: DEVICE: Bandage contact lens|DEVICE: Pressure patching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose Escalation Study to Determine the Safety of IFN-Beta Gene Transfer in the Treatment of Grade III & Grade IV Gliomas
Status: COMPLETED
Conditions: Glioblastoma Multiforme|Anaplastic Astrocytoma|Oligoastrocytoma, Mixed|Gliosarcoma
Interventions: GENETIC: Interferon-beta
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dietary Glycemic Index, Brain Function and Food Intake in Patients With Type 1 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: OTHER: high GI meal|OTHER: low GI meal|DRUG: euglycemic insulin clamp|DRUG: primed-variable insulin infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Scar Mobilization Versus Myofascial Cupping Technique on Cesarean Scar
Status: NOT_YET_RECRUITING
Conditions: Cesarean Section; Complications, Wound, Hematoma
Interventions: OTHER: Manual Scar Mobilization Therapy:|OTHER: Myofascial Cupping Therapy:
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessing the Effects of a Nasal Corticosteroid on PMI-150 (Intranasal Ketamine)
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: PMI-150 (intranasal ketamine HCl); mometasone furoate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Intrathecal Midazolam, Fentanyl and Nalbuphine as Adjuvants to Bupivacaine in Spinal Anesthesia for Cesarean Section
Status: COMPLETED
Conditions: Pain, Acute
Interventions: DRUG: Bupivacaine|DRUG: Fentanyl|DRUG: Nalbuphine|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Percutaneous Tibial Nerve Stimulation (PTNS) for the Treatment of Chronic Anal Fissure
Status: NOT_YET_RECRUITING
Conditions: Fissure in Ano
Interventions: DEVICE: PTNS
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Dose Escalation Study of Intensity Modulated Total Marrow Irradiation (IMRT-TMI) Followed by Fludarabine as a Myeloablative Conditioning Regimen for Allogeneic Hematopoietic Stem Cell Transplantation for Patients With Relapsed and Refractory Hematologic Malignancies
Status: WITHDRAWN
Conditions: Acute Myeloid Leukemia|Chronic Myeloid Leukemia|Acute Lymphocytic Leukemia|Myelodysplastic Syndromes
Interventions: COMBINATION_PRODUCT: Fludarabine + Total Marrow Irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase IB Study Of The BTKi CC-292 Combined With Lenalidomide In Adults Patients With Relapsed/Refractory B-Cell Lymphoma
Status: COMPLETED
Conditions: Relapsed/Refractory B-cell Lymphoma
Interventions: DRUG: CC-292 + lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Paclitaxel and DDP Combined With Anlotinib in the First-line Treatment for Patients With Advanced Esophageal Squamous Cell Carcinoma（ESCC）.
Status: UNKNOWN
Conditions: Esophageal Squamous Cell Carcinoma
Interventions: DRUG: Anlotinib Hydrochloride, Paclitaxel, cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Immediate Effects of Different Shoulder Stretching Techniques in Overhead Athletes
Status: NOT_YET_RECRUITING
Conditions: Glenohumeral Internal Rotation Deficit
Interventions: OTHER: Post Isometric Relaxation Group|OTHER: Isolytic Stretching Group|OTHER: Static Stretching Group Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Medical Radiometer - RTM - 01 - RES and Its Use in Detecting Hotspots in Female Breast
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: DEVICE: Microwave Thermography RTM-01-RES
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Immunogenicity and Safety of an Inactivated COVID-19 Vaccine in Elderly People With Chronic Bronchitis and COPD
Status: UNKNOWN
Conditions: COVID-19|Chronic Bronchitis|COPD
Interventions: BIOLOGICAL: Inactivated COVID-19 vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: 9-ING-41 in Patients With Advanced Cancers
Status: ACTIVE_NOT_RECRUITING
Conditions: Cancer|Pancreatic Cancer|Sarcoma|Renal Cancer|Refractory Cancer|Refractory Neoplasm|Refractory Non-Hodgkin Lymphoma|Pancreatic Adenocarcinoma|Resistant Cancer|Neoplasm Metastasis|Neoplasm of Bone|Neoplasm, Breast|Neoplasm of Lung|Neoplasms,Colorectal|Neoplasms Pancreatic|Malignant Glioma|Malignancies|Malignancies Multiple|Bone Metastases|Bone Neoplasm|Bone Cancer|Pancreas Cancer|Pancreatic Neoplasms|Breast Neoplasms|Acute T Cell Leukemia Lymphoma
Interventions: DRUG: 9-ING-41|DRUG: Gemcitabine - 21 day cycle|DRUG: Doxorubicin.|DRUG: Lomustine|DRUG: Carboplatin.|DRUG: Nab paclitaxel.|DRUG: Paclitaxel.|DRUG: Gemcitabine - 28 day cycle|DRUG: Irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Same-Day Discharge After Nipple-sparing Mastectomy or Skin-sparing Mastectomy With Breast Reconstruction
Status: UNKNOWN
Conditions: Breast Cancer|Mastectomy; Lymphedema|Same Day Surgery|Nipple-sparing Mastectomy|Skin-sparing Mastectomy
Interventions: PROCEDURE: Same-day NSM or SSM
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Risk Stratification Using Midregional Proadrenomedullin in the ED
Status: RECRUITING
Conditions: Patients Presenting With Suspicion of Infection to the ED
Interventions: DEVICE: MR-proADM KRYPTOR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Assessing the Procalcitonin-guidance and Molecular-guided Diagnosis for Therapy of Severe Infections (the MODIFY Trial)
Status: RECRUITING
Conditions: Sepsis
Interventions: DIAGNOSTIC_TEST: Change of antimicrobials based on BCID2 and Reveal Rapid AST tests. Stop of antimicrobials based on PCT results.|OTHER: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: CardiaMend and Amiodarone for the Prevention of POAF
Status: NOT_YET_RECRUITING
Conditions: POAF|Atrial Fibrillation
Interventions: COMBINATION_PRODUCT: CardiaMend with antiarrhythmic
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparison of Emergence and Oxygenation During One-lung Ventilation With Desflurane and Propofol Anesthesia
Status: ACTIVE_NOT_RECRUITING
Conditions: Lung Cancer
Interventions: DRUG: desflurane|DRUG: propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Study of Mesenchymal Stem Cells for the Treatment of Medically Refractory Crohn's Colitis
Status: UNKNOWN
Conditions: Crohn Colitis
Interventions: DRUG: Remestemcel-L|DRUG: Remestemcel-L|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Multiple Doses of BT061 in Patients With Moderate to Severe Chronic Plaque Psoriasis
Status: COMPLETED
Conditions: Psoriasis Vulgaris
Interventions: DRUG: BT061|DRUG: placebo treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: OPTION: A Trial to Assess the Safety & Efficacy of MS1819 in Patients With Exocrine Pancreatic Insufficiency Due to Cystic Fibrosis
Status: COMPLETED
Conditions: Exocrine Pancreatic Insufficiency (EPI)|Cystic Fibrosis (CF)
Interventions: DRUG: MS1819|DRUG: Porcine PERT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cyclophosphamide, Radiation Therapy, and Poly ICLC in Treating Patients With Unresectable, Recurrent, Primary, or Metastatic Liver Cancer
Status: UNKNOWN
Conditions: Breast Cancer|Colorectal Cancer|Gastric Cancer|Liver Cancer|Melanoma (Skin)|Metastatic Cancer|Ovarian Cancer|Pancreatic Cancer
Interventions: DRUG: cyclophosphamide|DRUG: poly ICLC|PROCEDURE: hepatic artery embolization|RADIATION: 3-dimensional conformal radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Nifedipine GITS and Candesartan Combination Compared to Monotherapy in Patients With Essential Hypertension
Status: COMPLETED
Conditions: Hypertension, Essential
Interventions: DRUG: Candesartan cilexetil (Atacand), 4 mg|DRUG: Candesartan cilexetil (Atacand), 8 mg|DRUG: Nifedipine GITS (Adalat, BAYA1040), 20 mg|DRUG: Nifedipine GITS (Adalat, BAYA1040), 30 mg|DRUG: Nifedipine GITS (Adalat, BAYA1040), 60 mg|DRUG: Placebo|DRUG: Candesartan cilexetil (Atacand), 16 mg|DRUG: Candesartan cilexetil (Atacand), 32 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Sacubitril/Valsartan Therapy on Biomarkers, Myocardial Remodeling and Outcomes.
Status: COMPLETED
Conditions: Heart Failure
Interventions: DRUG: LCZ696 (sacubitril/valsartan)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: B Cell Response to a Primary and a Booster Course of the Novartis Meningococcal ACWY Conjugate Vaccine in Healthy Infants
Status: COMPLETED
Conditions: Meningococcal Disease
Interventions: BIOLOGICAL: MenACWY-CRM|BIOLOGICAL: DTaP-Hib-IPV|BIOLOGICAL: PCV|BIOLOGICAL: MMR|BIOLOGICAL: Hib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: LimiFlex Clinical Trial for the Treatment of Degenerative Spondylolisthesis with Spinal Stenosis
Status: ACTIVE_NOT_RECRUITING
Conditions: Degenerative Spondylolisthesis|Lumbar Spinal Stenosis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BE Technologies Mobile Uroflowmetry Validation Study
Status: COMPLETED
Conditions: BPH|BPH With Urinary Obstruction With Other Lower Urinary Tract Symptoms|BPH Without Urinary Obstruction|BPH Without Urinary Obstruction With Other Lower Urinary Tract Symptoms|Lower Urinary Tract Symptoms|Overactive Bladder|Overactive Bladder Syndrome|Urinary Obstruction|Urinary Incontinence, Urge
Interventions: DEVICE: MenHealth Uroflowmeter
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Education in Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis|Quality of Life|Depression, Anxiety|Nurse's Role
Interventions: BEHAVIORAL: Education on disease management on the quality of life, and anxiety and depression about Rheumatoid Arthritis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Running Against Prehypertension Trial (RAPT): A Pilot Trial
Status: COMPLETED
Conditions: Prehypertension
Interventions: BEHAVIORAL: Educational material control|BEHAVIORAL: Group running style B|BEHAVIORAL: Group running style A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Atezolizumab and Bevacizumab Combination Recommended in a Multidisciplinary Consultation Meeting in Caen for Hepatocellular Carcinoma (ABCHCaen)
Status: COMPLETED
Conditions: Atezolizumab and Bevacizumab in Hepatocellular Carcinoma
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study Comparing Modified Lund Concept and Cerebral Perfusion Pressure-targeted Therapy in Secondary Brain Ischaemia.
Status: COMPLETED
Conditions: Brain Injuries|Subarachnoid Hemorrhage
Interventions: PROCEDURE: Modified Lund concept|PROCEDURE: Cerebral perfusion pressure-targeted therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Restrictive Eating Disorders: From Childhood Orality Disorder to Adolescent Dysensoriality
Status: COMPLETED
Conditions: Eating Disorders in Adolescence|Avoidant Restrictive Food Intake Disorder
Interventions: OTHER: Sensory Processing Scale Inventory (SPSI)|OTHER: Autism Spectrum Screening Quotient (ASSQ)|OTHER: GAD 7|OTHER: Conners abridged|OTHER: EAT 26
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Open- Label Trial of Sipuleucel-T Administered to Active Surveillance Patients for Newly Diagnosed Prostate Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Adenocarcinoma of the Prostate
Interventions: BIOLOGICAL: sipuleucel-T
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of the Use of Symbiotics in Patients With Colon Cancer
Status: UNKNOWN
Conditions: Symbiotic|Cancer Colorectal|Cancer Head Neck|Intestinal Dysbiosis|Diarrhea|Intestinal Microbiota|Nutritional Status
Interventions: DIETARY_SUPPLEMENT: Simbyotic|DEVICE: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Dose Escalation and Safety Study of Plasmin (Human) In Acute Lower Extremity Native Artery or Bypass Graft Occlusion
Status: COMPLETED
Conditions: Arterial Occlusive Diseases
Interventions: BIOLOGICAL: Plasmin (Human) 25 mg|BIOLOGICAL: Plasmin (Human) 50 mg|BIOLOGICAL: Plasmin (Human) 75 mg|BIOLOGICAL: Plasmin (Human) 100 mg|BIOLOGICAL: Plasmin (Human) 125 mg|BIOLOGICAL: Plasmin (Human) 150 mg|BIOLOGICAL: Plasmin (Human) 175 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Virtual Reality Epley Maneuver System (VREMS) for Treatment of Benign Paroxysmal Positional Vertigo
Status: UNKNOWN
Conditions: BPPV|Vertigo, Peripheral
Interventions: DEVICE: Virtual Reality Epley Maneuver System (VREMS)|OTHER: Instructional Handout (IH)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacogenetics of Doxazosin for Cocaine Dependence
Status: COMPLETED
Conditions: Cocaine Dependence
Interventions: DRUG: Doxazosin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Ultraviolet Radiation Forecasting Based Heliotherapy For Psoriasis in Bangkok, Thailand
Status: UNKNOWN
Conditions: Psoriasis Vulgaris
Interventions: OTHER: Heliotherapy (a sole sun-bathing)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Effects of One-Legged and Two-Legged Exercise Training on Exercise Capacity and Fatigue in Patients With Sarcoidosis
Status: ACTIVE_NOT_RECRUITING
Conditions: Pulmonary Sarcoidosis
Interventions: OTHER: Exercise- One-Legged|OTHER: Exercise-Two-Legged
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Magnetic Seizure Therapy (MST) for Treatment Resistant Major Depression
Status: COMPLETED
Conditions: Major Depression
Interventions: DEVICE: Thymatron|DEVICE: Tonica MagPro MST
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sapanisertib Before and After Surgery in Treating Patients With Recurrent Glioblastoma
Status: TERMINATED
Conditions: Glioblastoma|Gliosarcoma
Interventions: OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacological Study|DRUG: Sapanisertib|PROCEDURE: Therapeutic Conventional Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Cadazolid Versus Vancomycin in Subjects With Clostridium Difficile-associated Diarrhea
Status: COMPLETED
Conditions: Clostridium Difficile Infection
Interventions: DRUG: Cadazolid|DRUG: Vancomycin|DRUG: Cadazolid-matching placebo|DRUG: Vancomycin-matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Donepezil Double Blind Trial for ECT Memory Disfunction
Status: UNKNOWN
Conditions: Schizophrenia|Schizoaffective Disorder|Schizophreniform Disorder
Interventions: DRUG: Donepezil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Testing the Addition of an Antibody to Standard Chemoradiation Followed by the Antibody for One Year to Standard Chemoradiation Followed by One Year of the Antibody in Patients With Unresectable Stage III Non-Small Cell Lung Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Recurrent Lung Non-Small Cell Carcinoma|Stage III Lung Cancer AJCC v8|Stage IIIA Lung Cancer AJCC v8|Stage IIIB Lung Cancer AJCC v8|Stage IIIC Lung Cancer AJCC v8|Unresectable Lung Non-Small Cell Carcinoma
Interventions: DRUG: Carboplatin|DRUG: Cisplatin|BIOLOGICAL: Durvalumab|DRUG: Etoposide|DRUG: Paclitaxel|DRUG: Pemetrexed Disodium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Safety and Efficacy Study of Zilucoplan (RA101495) to Treat PNH Patients Who Have an Inadequate Response to Eculizumab
Status: COMPLETED
Conditions: Paroxysmal Nocturnal Hemoglobinuria (PNH)
Interventions: DRUG: Zilucoplan (RA101495)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: DUET Versus Standard Interface for Hypercapnic COPD Patients
Status: RECRUITING
Conditions: COPD Exacerbation|Hypercapnia|COPD
Interventions: DEVICE: Asymmetric nasal cannula - DUET|DEVICE: Conventional nasal high flow cannula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GLS-1200 Topical Nasal Spray to Prevent SARS-CoV-2 Infection (COVID-19)
Status: TERMINATED
Conditions: SARS-CoV 2|Infection
Interventions: DRUG: GLS-1200|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Exercise on Physical Function and Health in Older People After Discharge From Hospital
Status: COMPLETED
Conditions: Chest Pain|Pneumonia|Transient Ischemic Attack|Stroke|Functional Failure
Interventions: OTHER: Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: TENS Treatment Plus Ibuprofen for the Treatment of Acute Back Pain in the ED
Status: WITHDRAWN
Conditions: Low Back Pain
Interventions: DEVICE: TENS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Topical Chamomile in Preventing Chemotherapy-induced Oral Mucositis
Status: UNKNOWN
Conditions: Oral Mucositis Due to Chemotherapy
Interventions: DRUG: chamomile topical oral gel|DRUG: Miconazole Topical Gel|DRUG: BBC oral spray|DRUG: Oracure gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of A3309 in Patients With Dyslipidemia
Status: COMPLETED
Conditions: Dyslipidemia
Interventions: DRUG: A3309|DRUG: A3309|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: DEprescribing: Perceptions of PAtients Living With Advanced Cancer
Status: RECRUITING
Conditions: Deprescribing|Palliative Care|Oncology
Interventions: OTHER: Semi-directed individual interviews|OTHER: The self-administered questionnaires, rPATD and BMQ|OTHER: The self-administered FCCHL (Functional, Communicative and Critical Health Literacy) / HLS14 (14-item health literacy scale)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Test Efficacy, Safety, and Pharmacokinetics of Certolizumab Pegol in Children and Adolescents With Moderately to Severely Active Crohn's Disease
Status: WITHDRAWN
Conditions: Crohn's Disease
Interventions: DRUG: Certolizumab pegol|DRUG: Adalimumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety of ON 01910.Na and Irinotecan or ON 01910.Na and Oxaliplatin in Patients With Hepatoma
Status: COMPLETED
Conditions: Hepatoma|Advanced Solid Tumor
Interventions: DRUG: irinotecan and ON 01910.Na|DRUG: oxaliplatin and ON 01910.Na
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Colloids in Severe Trauma
Status: COMPLETED
Conditions: Abdominal Hypertension|Abdominal Compartment Syndrome|Severe Trauma
Interventions: DRUG: tetrastarch (Voluven)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Unenhanced Computed Tomography (CT) in Elderly Patients Admitted to the Emergency Department With Acute Abdominal Pain
Status: COMPLETED
Conditions: Abdominal Pain
Interventions: DEVICE: Unenhanced abdominal Computed Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Use of an Experimental Drug, CC-115, With Enzalutamide in Men With Castration-Resistant Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer|Castration Resistant Prostate Cancer
Interventions: DRUG: Enzalutamide|DRUG: CC-115
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Complement Inhibition With Eculizumab for the Treatment of Non-Exudative Macular Degeneration (AMD)
Status: COMPLETED
Conditions: Age-Related Macular Degeneration
Interventions: DRUG: Eculizumab|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Dry Needling on Muscle Stiffness, Gait, Motion, and Strength in Healthy Individuals With Trigger Points
Status: COMPLETED
Conditions: Trigger Point Pain, Myofascial
Interventions: OTHER: Dry Needling|OTHER: Sham Dry Needlling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Opiophobia in Postsurgical Adults With Cancer
Status: NOT_YET_RECRUITING
Conditions: Opiophobia
Interventions: OTHER: 13-item Barriers Questionnaire (BQ-13)|OTHER: Four-item Medication Adherence Questionnaire|OTHER: 14-item Hospital Anxiety and Depression Scale (HADS)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: THE EFFECT OF VIRTUAL REALITY ON CHILDREN'S ANXIETY, FEAR, AND PAIN LEVELS BEFORE CIRCUMCISION IN TURKEY
Status: COMPLETED
Conditions: to Have a Circumcision Operation
Interventions: PROCEDURE: Virtual Reality
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Regenerative Endodontics for Non-vital Primary Molars
Status: ACTIVE_NOT_RECRUITING
Conditions: Pulp and Periapical Tissue Disease
Interventions: PROCEDURE: Regeneration in primary molars by using MTA|PROCEDURE: Regeneration in primary molars by using biodentine|PROCEDURE: Conventional Root canal treatment in primary molars
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Healthy Tissue Preservation During Wound Debridement by Using Debritom+ Micro Water Jet Technology
Status: COMPLETED
Conditions: Wound Heal|Chronic Wound
Interventions: DEVICE: Debridement with Debritom+ micro water jet device|OTHER: Debridement with
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Diazoxide on the Obesity Secondary to Hypothalamic-pituitary Lesions
Status: COMPLETED
Conditions: Hypothalamic-pituitary Lesions|Craniopharyngiomas
Interventions: DRUG: DIAZOXIDE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study Comparing Conventional, Burst and High Frequency (HF) Spinal Cord Stimulation (SCS) in Refractory Failed Back Surgery Syndrome (FBSS) Patients After a 32-contact Surgical Lead Implantation
Status: COMPLETED
Conditions: Failed Back Surgery Syndrome
Interventions: DEVICE: Precision Spectra™ system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Potential Predictive Biological Markers of Major Depression Response to Citalopram Therapy in Anorexia Nervosa.
Status: RECRUITING
Conditions: Anorexia Nervosa
Interventions: DRUG: Citalopram i.v. and p.o|DRUG: Citalopram p.o
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Implementation of Support in the Care of Adults Living With Type 1 Diabetes
Status: NOT_YET_RECRUITING
Conditions: Type 1 Diabetes|Metabolic Disease|Endocrine System Diseases|Autoimmune Diseases|Immune System Diseases
Interventions: BEHAVIORAL: Support platform
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study to Evaluate Efficacy of Odanacatib (MK-0822) on Bone Mineral Density (BMD) and Bone Micro-architecture and Overall Safety in Postmenopausal Women (MK-0822-031)
Status: COMPLETED
Conditions: Osteoporosis
Interventions: DRUG: Odanacatib|DRUG: Placebo|DRUG: Vitamin D3|DRUG: Calcium supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Window Study of Nivolumab With or Without Ipilimumab in Squamous Cell Carcinoma of the Oral Cavity
Status: ACTIVE_NOT_RECRUITING
Conditions: Head and Neck Cancer
Interventions: DRUG: Nivolumab|DRUG: Ipilimumab|PROCEDURE: Standard of Care Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Dose-Finding Study of Vedolizumab for Treatment of Steroid-Refractory Acute Intestinal Graft-Versus-Host Disease (GvHD) in Participants Who Have Undergone Allogeneic Hematopoietic Stem Cell Transplantation (Allo-HSCT)
Status: TERMINATED
Conditions: Allogeneic Hematopoietic Stem Cell Transplantation
Interventions: DRUG: Vedolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Splenic Artery Ligation and Portocaval Shunt in Small-for-size Syndrome
Status: COMPLETED
Conditions: Small-For-Size Liver Syndrome|Ligation|Liver Regeneration|Splenic Artery|Portal Vein|Ischemia|Reperfusion Injury|Hepatectomy
Interventions: PROCEDURE: splenic artery ligation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison Between Early-onset and Late-onset Patients With Systemic Lupus Erythematosus.
Status: ENROLLING_BY_INVITATION
Conditions: Systemic Lupus Erythematosus
Interventions: DIAGNOSTIC_TEST: CBC|DIAGNOSTIC_TEST: Antinuclear Antibody tests (ANA)|DIAGNOSTIC_TEST: Rest of ANA profile|DIAGNOSTIC_TEST: C3 and C4 complement level.|DIAGNOSTIC_TEST: Anti phospholipid marker|DIAGNOSTIC_TEST: Serum creatinine and Alb/create ratio|OTHER: 2019 European League Against Rheumatism/American College of Rheumatology classification criteria for systemic lupus erythematosus.|OTHER: SLEDAI scores
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Home-based Exercise Rehabilitation With a Novel Digital Biofeedback System for Chronic Low Back Pain
Status: WITHDRAWN
Conditions: Non-specific Chronic Low Back Pain
Interventions: DEVICE: Home-based rehabilitation with a digital biofeedback system|OTHER: Conventional home-based rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Follow-up of the Nasal Microbiome and Viral Infections in Newborns Hospitalised in Neonatology.
Status: COMPLETED
Conditions: Microbial Colonization|Viral Infection|Neonatal Infection
Interventions: DIAGNOSTIC_TEST: Nasal swab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of NAC of GA Therapy for Patients With BRPC
Status: UNKNOWN
Conditions: Pancreatic Ductal Adenocarcinoma
Interventions: DRUG: Neoadjuvant chemotherapy of gemcitabine plus nab-paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Switching From a Tenofovir Disoproxil Fumarate (TDF) Containing Regimen to Elvitegravir/Cobicistat/Emtricitabine/ Tenofovir Alafenamide (E/C/F/TAF) Fixed-Dose Combination (FDC) in Virologically-Suppressed, HIV-1 Infected Adults Aged ≥ 60 Years
Status: COMPLETED
Conditions: HIV-1 Infection
Interventions: DRUG: E/C/F/TAF|DRUG: TDF|DRUG: FTC|DRUG: FTC/TDF|DRUG: 3TC|DRUG: Third agent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial in Healthy Volunteers to Study the Safety, Tolerability, and Immune Responses After Vaccination With an Investigational Vaccine Designed to Prevent Genital Herpes Lesions
Status: RECRUITING
Conditions: Genital Herpes Simplex Type 2
Interventions: BIOLOGICAL: BNT163|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Ketone Ester Consumption on Exercise Tolerance and Cardiac Function
Status: RECRUITING
Conditions: Heart Failure With Preserved Ejection Fraction|Type 2 Diabetes|Metabolic Syndrome
Interventions: DIETARY_SUPPLEMENT: C8 Ketone Supplement|DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: Ketone Ester Acute|DIETARY_SUPPLEMENT: Placebo Acute
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Active You: A Novel Exercise Program for African Americans
Status: COMPLETED
Conditions: Cardiovascular Risk Factor|Prediabetes|Overweight and Obesity|Sedentary Behavior
Interventions: BEHAVIORAL: The Physical Activity for The Heart (PATH) intervention|BEHAVIORAL: Be Active Your Way Booklet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Induction Chemotherapy Followed by Concurrent Chemoradiotherapy for Nasopharyngeal Carcinoma (NPC)
Status: UNKNOWN
Conditions: Nasopharyngeal Carcinoma
Interventions: DRUG: docetaxel, cisplatin, fluorouracil|RADIATION: 3D-CRT (three-dimensional conformal radiation therapy) or IMRT (intensity-modulated radiation therapy)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Specified Drug-Use Survey of Trelagliptin Tablets "Survey on Long-term Use in Type 2 Diabetes Mellitus Patients With Severe Renal Impairment or End-stage Renal Disease"
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Trelagliptin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Virtual Reality Experiences for Anxiety and Pain Control
Status: COMPLETED
Conditions: Hematopoietic and Lymphoid Cell Neoplasm|Malignant Solid Neoplasm
Interventions: OTHER: Survey Administration|PROCEDURE: Virtual Reality Game|PROCEDURE: Virtual Reality Meditation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Safety and Efficacy of SNC-109 CAR-T Cells Therapy the Recurrent Glioblastoma
Status: RECRUITING
Conditions: Recurrent Glioblastoma Multiforme
Interventions: DRUG: SNC-109 CAR-T Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improving Treatment of Nontuberculous Mycobacterial Infection in Cystic Fibrosis
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: Ethambutol|DRUG: Rifampin|DRUG: Azithromycin|DRUG: Pancrelipase
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fludarabine and Cyclophosphamide in Treating Patients Who Are Undergoing Donor Stem Cell Transplant for Chronic Lymphocytic Leukemia or Waldenstrom's Macroglobulinemia
Status: COMPLETED
Conditions: Chronic Lymphocytic Leukemia
Interventions: BIOLOGICAL: alemtuzumab|BIOLOGICAL: anti-thymocyte globulin|BIOLOGICAL: filgrastim|BIOLOGICAL: rituximab|BIOLOGICAL: therapeutic allogeneic lymphocytes|DRUG: busulfan|DRUG: cyclophosphamide|DRUG: cyclosporine|DRUG: fludarabine phosphate|DRUG: methotrexate|DRUG: mycophenolate mofetil|PROCEDURE: peripheral blood stem cell transplantation|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of Trelagliptin Succinate Tablets in the Treatment of Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Trelagliptin Succinate|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Oxaliplatin, Gemcitabine, and Erlotinib Study in Patients With Advanced Chemo-naïve Pancreatic Cancer
Status: TERMINATED
Conditions: Pancreatic Cancer
Interventions: DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cognitive Enhancement Program in Improving Cognitive Function in Breast Cancer Survivors
Status: WITHDRAWN
Conditions: Breast Cancer|Cancer Survivor|Cognitive/Functional Effects
Interventions: OTHER: computer-assisted cognitive training|OTHER: cognitive intervention|PROCEDURE: mind-body intervention procedure|OTHER: memory intervention|OTHER: questionnaire administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Randomized Trial Comparing the Live Birth Rate of Immediate Versus Delayed FET Following a Freeze-all Strategy
Status: RECRUITING
Conditions: IVF|Frozen Embryo Transfer
Interventions: PROCEDURE: Immediate FET|PROCEDURE: Delayed FET
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety, Tolerability and Preliminary Efficacy Study of LiRIS® 400 mg in Women With Interstitial Cystitis (IC) and Hunner's Lesions
Status: COMPLETED
Conditions: Chronic Interstitial Cystitis
Interventions: DRUG: LiRIS® 400 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transesophageal Echocardiography: Dysphagia Risk in Acute Stroke (T.E.D.R.A.S. Trial)
Status: COMPLETED
Conditions: Acute Stroke|Dysphagia|Swallowing Disorder
Interventions: DIAGNOSTIC_TEST: Transesophageal Echocardiography (TEE)|DIAGNOSTIC_TEST: Flexible Endoscopic Evaluation of Swallowing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Ocular Bandage Gel (OBG) Pivotal Trial in Patients Undergoing Photorefractive Keratectomy ("PRK")
Status: COMPLETED
Conditions: Ophthalmology|Photorefractive Keratectomy ("PRK")|Laser Assisted Surgery|Refractive Surgery
Interventions: DEVICE: Ocular Bandage Gel (OBG)|DEVICE: Bandage Contact Lens (BCL)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT