pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Evaluating Modifiable Biomarkers for the Prediction of Immunotherapy Response and Toxicity
Status: RECRUITING
Conditions: Lung Non-Squamous Non-Small Cell Carcinoma|Stage IIIB Lung Cancer AJCC v8|Stage IV Lung Cancer AJCC v8|Stage IVA Lung Cancer AJCC v8|Stage IVB Lung Cancer AJCC v8
Interventions: PROCEDURE: Biospecimen Collection|OTHER: Physical Performance Testing|OTHER: Physical Performance Testing|OTHER: Questionnaire Administration
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study Evaluating Persistence of Anti-HBs Antibodies in Uraemic Patients Receiving Henogen's HBV Vaccine, or Fendrix™
Status: COMPLETED
Conditions: Hepatitis B
Interventions: BIOLOGICAL: Henogen HB vaccine|BIOLOGICAL: Fendrix vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Value of Diffusion Weighted Magnetic Resonance Imaging in Detection of Recurrent Disease in Surgically Treated Cervical and Endometrial Cancer Patients
Status: UNKNOWN
Conditions: Cervical Cancer|Endometrial Cancer
Interventions: DEVICE: Diffusion weighted MRI (DW- MRI)- Philips Achieva 3.0T X, Netherlands, 2011
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Veliparib With Carboplatin and Paclitaxel and as Continuation Maintenance Therapy in Adults With Newly Diagnosed Stage III or IV, High-grade Serous, Epithelial Ovarian, Fallopian Tube, or Primary Peritoneal Cancer
Status: TERMINATED
Conditions: Ovarian Cancer|Ovarian Neoplasm
Interventions: DRUG: Veliparib|DRUG: Paclitaxel|DRUG: Carboplatin|OTHER: Placebo to Veliparib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dexmedetomidine Reduces Atrial Fibrillation in Mechanically Ventilated Patients With COVID-19 Pneumonia
Status: UNKNOWN
Conditions: COVID-19 Pneumonia|Atrial Fibrillation
Interventions: PROCEDURE: Dexmedetomidine sedation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Neo-DAB: Darolutamide and Abemaciclib in Prostate Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Prostate Cancer|Non-metastatic Prostate Cancer|Prostate Cancer
Interventions: DRUG: Darolutamide|DRUG: Abemaciclib|DRUG: GNRH-A Leuprolide Acetate|DRUG: GNRH-A Goserelin|DRUG: Degarelix
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Programmed Death-1(PD-1) Inhibitor Combined With Progesterone Treatment in Endometrial Cancer
Status: UNKNOWN
Conditions: Endometrial Cancer Stage I
Interventions: DRUG: PD-1 inhibitor combined progesterone|DRUG: progesterone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluate Efficacy and Safety of XELOX in Potentially Resectable Liver Metastasis From Colorectal Cancer(CRC)
Status: UNKNOWN
Conditions: Potentially Resectable Liver Metastasis From CRC|Colorectal Cancer
Interventions: DRUG: Capecitabine plus oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cancer Associated Thrombosis, a Pilot Treatment Study Using Rivaroxaban
Status: COMPLETED
Conditions: Neoplasm|Venous Thromboembolism
Interventions: DRUG: rivaroxaban|DRUG: Low-molecular-weight heparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, and Efficacy of MatriPlax in Subjects With Acute Respiratory Distress Syndrome
Status: NOT_YET_RECRUITING
Conditions: Acute Respiratory Distress Syndrome
Interventions: DRUG: MatriPlax
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fourteen-Day Vonoprazan-Based Dual Therapy With Amoxicillin as First-Line Helicobacter Pylori Treatment in Comparison With Extended Sequential Therapy
Status: RECRUITING
Conditions: Helicobacter Pylori Infection
Interventions: DRUG: Vonoprazan and Amoxicillin|DRUG: Lansoprazole, Amoxicillin, Clarithromycin and Metronidazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Total Knee Replacement Using Simplex® or Cobalt™ Bone Cement
Status: WITHDRAWN
Conditions: Osteoarthritis|Rheumatoid Arthritis|Traumatic Arthritis|Knee Arthritis
Interventions: DEVICE: Simplex® Bone Cement|DEVICE: Cobalt™ Bone Cement
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Technology and Health Communication in Improving Health Outcomes in Patients Scheduled for Mammography
Status: COMPLETED
Conditions: Female Breast Carcinoma|Healthy Subject
Interventions: OTHER: Questionnaire Administration|BEHAVIORAL: Telephone-Based Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: To Assess the Efficacy and Safety of SCD-044 in the Treatment of Moderate to Severe Atopic Dermatitis
Status: ACTIVE_NOT_RECRUITING
Conditions: Dermatitis, Atopic
Interventions: DRUG: Placebo|DRUG: SCD-044_Dose 1|DRUG: SCD-044_Dose 2|DRUG: SCD-044_Dose 3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Durvalumab (MEDI4736) Plus Platinum-based Chemotherapy in Advanced LCNEC: a Pilot Phase II Study
Status: RECRUITING
Conditions: Patients With Advanced Treatment Naive LCNEC
Interventions: DRUG: Durvalumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Level of Agreement Between Clinical Defocus Curves and the Web-based Democritus Digital Acuity Reading Test wDDART
Status: UNKNOWN
Conditions: Presbyopia|Near Vision
Interventions: DIAGNOSTIC_TEST: Defocus curves - Monocular distance visual acuity with trial lenses added to the best correction for distance|DIAGNOSTIC_TEST: wDDART - Monocular near visual acuity using the best correction for distance
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Single-center, Multi-cohort Exploratory Phase Ib/II Clinical Study of First-line Treatment of Unresectable Locally Advanced/Advanced Adenocarcinoma of the Stomach or Gastroesophageal Junction Based on Different Genotypes
Status: NOT_YET_RECRUITING
Conditions: Gastric Cancer|Gastroesophageal-junction Cancer
Interventions: DRUG: IBI315|DRUG: Oxaliplatin|DRUG: Capecitabine|DRUG: TST001|DRUG: TQB2450|DRUG: Anrotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Efficacy Study of ABT-089 in Adults With Attention-Deficit/Hyperactivity Disorder (ADHD)
Status: COMPLETED
Conditions: Attention-Deficit/Hyperactivity Disorder
Interventions: DRUG: ABT-089|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Branched-chain Amino Acids (BCAA) to Muscle Cramps in Patients With Cirrhosis
Status: COMPLETED
Conditions: Muscle Cramp|Cirrhosis|Quality of Life
Interventions: DRUG: Branched-chain Amino Acid|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Healthcare Providers as Trusted Messengers to Increase Receipt of Tax Credits Among Low-income Families
Status: RECRUITING
Conditions: Depression|Child Development|Stress|Physical Illness|Health Care Utilization
Interventions: BEHAVIORAL: Healthcare provider referral to a tax filing app
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Preheating of Femur Component in Hybrid Total Hip Arthroplasty
Status: COMPLETED
Conditions: Osteoarthritis, Hip
Interventions: PROCEDURE: Total hip replacement (Preheating of femur stem)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of IgPro10 in Adults With Systemic Sclerosis (SSc)
Status: WITHDRAWN
Conditions: Diffuse Cutaneous Systemic Sclerosis
Interventions: BIOLOGICAL: IgPro10|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Self-monitoring of Blood Pressure and Self-titration of Medication in the Control of Hypertension (ADAMPA)
Status: COMPLETED
Conditions: Hypertension|Adjustment|Adherence, Medication
Interventions: OTHER: Self-monitoring/Self-titration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Hamstring Muscle Strength After ACL Hamstring Reconstruction
Status: COMPLETED
Conditions: Anterior Cruciate Ligament Rupture
Interventions: PROCEDURE: ACL hamstring reconstructions using semitendinosus (ST) tendon only|PROCEDURE: ACL hamstring reconstructions using semitendinosus and gracilis (ST/G) tendon
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: SD-OCT Angiography
Status: TERMINATED
Conditions: Neovascular Age-related Macular Degeneration|Age-related Macular Degeneration|Diabetic Retinopathy|Retinal Vein Occlusion|Diabetic Macular Edema
Interventions: DEVICE: AngioVue SD-OCT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study of 99mTc-3PRGD2 Injection in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: 99mTc niacinamide polyethylene glycol bicyclic RGD peptide (99mTc-3PRGD2)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Clinical Trial of Immediate Skin to Skin Contact at Birth Early vs. Immediate (CPPITLH)
Status: UNKNOWN
Conditions: Breast Feeding
Interventions: OTHER: Skin to skin contact immediate|OTHER: skin to skin contact early
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Liraglutide on the Beta-cell Responsiveness in Subjects With Type 2 Diabetes Compared to a Healthy Control Group
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: liraglutide|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Twinkle Eyez Supplementation in Improving Ocular Health and Immunity
Status: COMPLETED
Conditions: Dry Eye Disease|Immunity
Interventions: DIETARY_SUPPLEMENT: Twinkle Eyez Supplementation|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Methoxyamine and Temozolomide in Treating Patients With Advanced Solid Tumors
Status: COMPLETED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: Methoxyamine|DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multiple-Dose Pharmacokinetics and Potential for Adrenal Suppression Following Treatment With Halobetasol Spray in Patients With Atopic Dermatitis
Status: TERMINATED
Conditions: Atopic Dermatitis
Interventions: DRUG: Treatment with Halobetasol propionate 0.05% topical spray
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hacettepe University COVID-19 Vaccinated's Health Cohort- Students of Health Sciences
Status: COMPLETED
Conditions: COVID-19 Pandemic|SARS-CoV2 Infection|Immunization; Infection|Health
Interventions: OTHER: Observational, prospective, follow-up of the recipients of CoronaVac (inactivated), Pfizer-Biontech (mRNA) vaccines
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy of Over-glasses Patch Treatment for Amblyopia in Children : OPTA Study
Status: COMPLETED
Conditions: Amblyopia
Interventions: DEVICE: over-glasses patch|DEVICE: Conventional patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Fluzoparib Combined With Apatinib as Second-Line Treatment of Patients With Extensive Stage Small Cell Lung Cancer（FA-ES-SCLC）
Status: UNKNOWN
Conditions: Small Cell Lung Cancer Extensive Stage
Interventions: DRUG: Fluzoparib|DRUG: Apatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Inflammation Following Mepolizumab and Oral Corticosteroids in Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Prednisolone|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Chinese Herbal Medicine for Psoriasis Vulgaris: a Real World Study
Status: UNKNOWN
Conditions: Psoriasis
Interventions: DRUG: Oral Chinese Herbal Medicine of Clearing heat and Cooling blood therapy|DRUG: Oral Chinese Herbal Medicine according with syndrome differentiation therapy|DRUG: Oral Chinese Herbal Medicine of Promoting blood circulation and Removing blood stasis therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prediction of Local Recurrence and Its Impact on Long-term Outcomes After Low-risk Glans-sparing Surgery for Penile Squamous Cell Carcinoma
Status: ENROLLING_BY_INVITATION
Conditions: Penile Cancer, Recurrent
Interventions: PROCEDURE: Glans-sparing surgery
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Efficacy of TaurusOne® Transcatheter Aortic Valve System in Patients With Severe Calcific Aortic Stenosis
Status: ACTIVE_NOT_RECRUITING
Conditions: Aortic Stenosis
Interventions: DEVICE: TaurusOne® transcatheter aortic valve replacement system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Food Study of Nitrofurantoin Monohydrate/Macrocrystals Capsules 100 mg and Macrobid® Capsules 100 mg
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Nitrofurantoin Monohydrate/Macrocrystals Capsules 100 mg|DRUG: Macrobid® Capsules 100 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: MEthotrexate Versus TOcilizumab for Treatment of GIant Cell Arteritis: a Multicenter, Randomized, Controlled Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Giant Cell Arteritis
Interventions: DRUG: Prednisone treatment|DRUG: Tocilizumab treatment|DRUG: Methotrexate treatment|OTHER: Questionnaires|BIOLOGICAL: Blood samples
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of a Single Session of Intermittent Hypoxia on Hematological Variables
Status: COMPLETED
Conditions: Intermittent Hypoxia
Interventions: BEHAVIORAL: Intermittent hypoxia|BEHAVIORAL: Intermittent normoxia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effects of Costovertebral Joint Mobilization on Respiratory Function in Asthmatic Patients
Status: COMPLETED
Conditions: Asthmatic
Interventions: OTHER: Costovertebral mobilizations + Conventional PT|OTHER: Conventional treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Statin Association With Standard Treatment in Prevention of Recurrent Hemorrhage in Patient With Cirrhosis and Variceal Bleeding
Status: COMPLETED
Conditions: Cirrhosis|Hypertension, Portal|Bleeding Esophageal Varices|Portal Vein Thrombosis
Interventions: DRUG: Simvastatin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effective Care Management of Depressed Diabetes Patients (The Positive Steps Study)
Status: COMPLETED
Conditions: Diabetes|Depression
Interventions: BEHAVIORAL: Medication Care Management (MCM)|BEHAVIORAL: Cognitive-Behavioral Therapy (CBT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: High-Intensity-Interval-Training in Geriatric Rehabilitation - A Feasibility Study
Status: UNKNOWN
Conditions: Rehabilitation|Post-Operative Condition|Deconditioning After Acute Hospital|Oncology
Interventions: OTHER: High Intensity Interval Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Intra-tracheal Instillation of Budesonide to Prevent Chronic Lung Disease
Status: RECRUITING
Conditions: Infant, Extremely Premature|Acute Lung Injury|Chronic Lung Disease of Prematurity|Budesonide
Interventions: DRUG: Infants in the study group (S/B group) will receive surfactant 2.5 mls/kg and Budesonide 0.5 mg (1mL)|DRUG: Infants in the control group (S/P group) receive placebo (Normal saline 1mL)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Corticosteroid Therapy in Refractory Shock Following Cardiac Arrest
Status: COMPLETED
Conditions: Cardiac Arrest
Interventions: DRUG: Normal Saline|DRUG: Hydrocortisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The ISET (Isolation by Size of Epithelial Tumor Cells) and the CellSearch Methods in Malignant Pleural Mesothelioma
Status: COMPLETED
Conditions: Pleural Neoplasms|Mesothelioma|Pneumothorax|Parathyroid Neoplasms|Benign Tumor of the Thyroid|Tumor of the Thyroid
Interventions: OTHER: Blood sampling|OTHER: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of LY3113593 in Healthy Participants and Participants With Chronic Kidney Disease Treated With Hemodialysis
Status: COMPLETED
Conditions: Kidney Failure, Chronic
Interventions: DRUG: LY3113593|DRUG: LY3113593|DRUG: Placebo|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Plaque Prolapse Prevention Carotid Artery Stenting (3PCAS)
Status: COMPLETED
Conditions: Cerebrovascular Disease
Interventions: PROCEDURE: Carotid stenting procedure by carotid stent implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PLX51107 and Azacitidine in Treating Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome
Status: COMPLETED
Conditions: Acute Myeloid Leukemia|Myelodysplastic Syndrome|Myelodysplastic/Myeloproliferative Neoplasm|Myeloproliferative Neoplasm
Interventions: DRUG: Azacitidine|DRUG: BRD4 Inhibitor PLX51107
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevention of Child Mental Health Problems in Southeastern Europe (RISE) - A Factorial Study (Phase 2 of MOST)
Status: COMPLETED
Conditions: Child Mental Disorder
Interventions: BEHAVIORAL: Parenting for Lifelong Health (PLH)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Does Acupressure Affect Gastrointestinal Function, Pain and Anxiety?
Status: COMPLETED
Conditions: Gastrointestinal Dysfunction|Anxiety|Pain, Postoperative
Interventions: OTHER: Acupressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effectiveness of Bupropion Combined With Behavioral Therapy for Treating Methamphetamine Dependence - 2
Status: COMPLETED
Conditions: Methamphetamine
Interventions: DRUG: Bupropion|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Experimental Medication BMS-986251, Taken by Mouth, in Healthy Participants and Patients With Average to Very Serious Psoriasis
Status: TERMINATED
Conditions: Rheumatoid Arthritis|Psoriasis|Ankylosing Spondylitis|Inflammatory Bowel Diseases|Nonalcoholic Steatohepatitis
Interventions: DRUG: BMS-986251|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Post-market Clinical Follow-up of a Magnetic Bone Conduction Implant (Cochlear Baha Attract System)
Status: COMPLETED
Conditions: Deafness|Hearing Loss|Hearing Loss, Conductive
Interventions: DEVICE: Baha Attract System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Safety, Efficacy and Pharmacokinetic Profile of Multiple Doses of QL-007 in Chronic Hepatitis B Patients
Status: UNKNOWN
Conditions: Chronic Hepatitis b
Interventions: DRUG: QL-007 tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preoperative Ketorolac for Pain Control in Scleral Buckle Surgery
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Ketorolac Tromethamine|DRUG: placebo|PROCEDURE: scleral buckle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Trial to Assess Efficacy and Safety of Ex Vivo Allograft Admin of ICM012 Solution 2 Mg/ml to Improve Its Function in Recipients of DCD Kidneys
Status: NOT_YET_RECRUITING
Conditions: Ischemia-reperfusion Injury|Kidney Transplant; Complications
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Quadratus Lumborum vs Caudal Epidural Block for Perioperative Analgesia in Pediatric Patients for Upper Abdominal Surgeries
Status: RECRUITING
Conditions: Post Operative Pain, Acute
Interventions: PROCEDURE: Quadratus lumborum block|PROCEDURE: Caudal epidural injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Erector Spina Plane Block and Radiofrequency Treatmen
Status: COMPLETED
Conditions: Back Pain|Block|Pain, Muscle
Interventions: PROCEDURE: Erector spina plane block|PROCEDURE: Erector spina bale block and pulsed radiofrequency
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lipopeptide Immunisation With GTU-multiHIV Trial
Status: COMPLETED
Conditions: HIV-1 Infection
Interventions: BIOLOGICAL: Placebos of GTU-multiHIV B and LIPO-5 vaccines|BIOLOGICAL: GTU-multHIV B vaccine and LIPO-5 vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Collaborative Healthcare Professionals Approach in Monitoring of Patient Centered Outcomes Through Pathways
Status: COMPLETED
Conditions: Heart Failure|Community Acquired Pneumonia|Venous Thromboembolism|Acute Kidney Injury|Asthma
Interventions: OTHER: Pathway-Based Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study of NMDA Antagonists and Neuropathic Pain
Status: COMPLETED
Conditions: Neuropathic Pain
Interventions: DRUG: Dextromethorphan (drug used like antitussive)|DRUG: Memantine (drug used in Alzheimer's disease)|DRUG: Placebo (lactose)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Psychedelic VR-augmented Therapy on Patients With Clinical Depression
Status: RECRUITING
Conditions: Depression
Interventions: OTHER: Therapeutic Intervention with Psychedelic Virtual Reality|OTHER: Therapeutic Intervention with Non-Psychedelic Virtual Reality
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Synthetic Vaccine in Patients With Chronic Myeloid Leukemia and Minimal Residual Disease
Status: COMPLETED
Conditions: Chronic Myeloid Leukemia|Minimal Residual Disease
Interventions: BIOLOGICAL: Synthetic Tumor-Specific Breakpoint Peptide Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Dry Needling in Shortened Triceps Surae Muscle
Status: COMPLETED
Conditions: Trigger Point Pain, Myofascial|Myofascial Pain Syndrome
Interventions: OTHER: Dry needling|OTHER: Ischemic compression
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: First in Human Study of ALS-002158; Single Dose, Food Effect in Healthy Volunteers; Multiple Doses in Chronic Hepatitis C Genotype 1
Status: TERMINATED
Conditions: Hepatitis C, Chronic
Interventions: DRUG: ALS-002158|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Early Human Milk Fortification After Early, Exclusive, Enteral Nutrition in Very Preterm Infants
Status: ACTIVE_NOT_RECRUITING
Conditions: Prematurity|Light-For-Dates|Enteral Feeding Intolerance
Interventions: DIETARY_SUPPLEMENT: Early HMF|DIETARY_SUPPLEMENT: Delayed HMF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy of Venetoclax With Escalating Doses of Omacetaxine in Patients With Acute Myeloid Leukemia Safety and Efficacy of Venetoclax With Escalating Doses of Omacetaxine in Patients With Acute Myeloid Leukemia (AML)
Status: RECRUITING
Conditions: Relapsed or Refractory Hematologic Malignancies
Interventions: DRUG: Omacetaxine|DRUG: Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Optimizing Extension Study of Chronic Hepatitis B Patients With Inadequate Response to NUC Therapy
Status: UNKNOWN
Conditions: Chronic Hepatitis B|Inadequate Response|Nucleos(t)Ide Analogues Treatment
Interventions: DRUG: Entecavir, Adefovir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation the Efficacy Between Botox Injection and Combination Pharmacotherapy in Patients With Detrusor Overactivity
Status: RECRUITING
Conditions: Urinary Bladder, Overactive|Urodynamics|Effect of Drug
Interventions: PROCEDURE: Intradetrusor Botox® (onabotulinumtoxinA) injection|DRUG: Combine Mirabegron and Solifenacin.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Aspirin Mouthwash in Treating Patients With Oral Leukoplakia
Status: COMPLETED
Conditions: Precancerous Condition
Interventions: DRUG: acetylsalicylic acid|GENETIC: gene expression analysis|GENETIC: protein expression analysis|OTHER: laboratory biomarker analysis|OTHER: questionnaire administration|PROCEDURE: biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lapatinib In Combination With Trastuzumab Versus Lapatinib Monotherapy In Subjects With HER2-positive Metastatic Breast Cancer
Status: COMPLETED
Conditions: Neoplasms, Breast
Interventions: DRUG: Lapatinib|BIOLOGICAL: Trastuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study on the Effects of Two Nicotine Replacement Products on Tooth Staining
Status: COMPLETED
Conditions: Tobacco Dependence
Interventions: DRUG: Nicotine|DRUG: Nicotine|DRUG: Nicotine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Combination Chemotherapy and Radiation Therapy in Treating Patients With Stage III Non-Small Cell Lung Cancer That Cannot Be Removed by Surgery
Status: UNKNOWN
Conditions: Lung Cancer
Interventions: DRUG: cisplatin|DRUG: etoposide|DRUG: irinotecan hydrochloride|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study of Rapid Haplotyping Procedure for Personalized Dosing of Dichloroacetate (DCA) in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Dichloroacetate (DCA)|OTHER: GSTZ1 haplotyping
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: S-1 and Oxaliplatin (SOX) Plus Sintilimab in the Locally Advanced Esophagogastric Junction Adenocarcinoma
Status: RECRUITING
Conditions: Locally Advanced Gastroesophageal Junction Adenocarcinoma|Chemotherapy Effect
Interventions: DRUG: Oxaliplatin+S-1|DRUG: Sinitilimab+oxaliplatin+S-1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Oropharyngeal Administration of Colostrum
Status: COMPLETED
Conditions: Health Behavior
Interventions: BIOLOGICAL: Oropharyngeal administration of own mother's colostrum|OTHER: Oropharyngeal administration of sterile water (placebo)|BIOLOGICAL: Oropharyngeal administration of donor human milk
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Immunogenicity & Safety Study of Fluviral® (2010 - 2011 Season) in Adults Aged 18 to 60 Years and Over 60 Years
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Fluviral®
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Phase 2/3 Open-label Extension Study to Evaluate Long-Term Safety and Efficacy With VX-509 in Subjects With Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: VX-509
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Perioperative Treatment in Resectable Gastric Cancer With Spartalizumab (PDR001) in Combination With Fluorouracil, Leucovorin, Oxaliplatin, and Docetaxel (FLOT)
Status: ACTIVE_NOT_RECRUITING
Conditions: Gastric Cancer by AJCC V8 Stage|Resectable Carcinoma
Interventions: DRUG: perioperative treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Evaluation of Blood Glucose Meter Systems
Status: COMPLETED
Conditions: Diabetes
Interventions: DEVICE: CONTOUR® NEXT EZ BGMS|DEVICE: FreeStyle Freedom Lite® BGMS|DEVICE: ACCU-CHEK® Aviva BGMS|DEVICE: TRUEtrack® BGMS|DEVICE: OneTouch® Ultra®2 BGMS
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Influence of Catheter Ablation for Atrial Fibrillation on Atrial Electrical
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: PROCEDURE: radiofrequency ablation or cryoballoon
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Treatment Using Capravirine (AG1549), Nelfinavir, and Two Nucleoside Reverse Transcriptase Inhibitors in HIV Patients Who Failed Initial Combination Therapy
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Capravirine|DRUG: Nelfinavir mesylate
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: A Study of CRLX101(NLG207) in Combination With Weekly Paclitaxel in Patients With Recurrent or Persistent Epithelial Ovarian, Fallopian Tube or Primary Peritoneal Cancer
Status: TERMINATED
Conditions: Ovarian Cancer
Interventions: DRUG: CRLX101|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study Comparing Two Tablet Formulations of Tebipenem Pivoxil Hydrobromide (TBPM-PI-HBr) in Healthy Adult Subjects
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Tebipenem pivoxil hydrobromide (TBPM-PI-HBr) - Reference|DRUG: Tebipenem pivoxil hydrobromide (TBPM-PI-HBr) - Test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Pembrolizumab In Central Nervous System Metastases
Status: ACTIVE_NOT_RECRUITING
Conditions: Brain Metastases
Interventions: DRUG: Pembrolizumab|RADIATION: MRI|RADIATION: PET/CT|PROCEDURE: Stereotactic Radiosurgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effects of a Food Supplementation on the Improvement of Cognitive Functions in Healthy Seniors
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DIETARY_SUPPLEMENT: Verum|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Pyridostigmine Efficacy and Safety for Treatment of Ileus After Colorectal Surgery
Status: NOT_YET_RECRUITING
Conditions: Postoperative Ileus
Interventions: DRUG: Pyridostigmine Bromide|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Spirometry as a Motivational Tool to Quit Smoking
Status: COMPLETED
Conditions: Smoking Cessation|COPD
Interventions: BEHAVIORAL: Spirometry and a brief advice to quit smoking|BEHAVIORAL: Brief advice to quit smoking
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluation of the Safety, Tolerability and Pharmacokinetics of Repeat Oral Doses of GSK580416
Status: TERMINATED
Conditions: Bacterial Infection|Infections, Bacterial
Interventions: DRUG: GSK580416 oral tablets (250 mg) Ketoconazole oral tablets (200 mg)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultra-high Frequency (500 KHz) Spinal Cord Stimulation for Treatment of Chronic Back Pain or Lower Limb Pain
Status: COMPLETED
Conditions: Pain, Chronic|Pain, Back|Pain, Radiating
Interventions: DEVICE: GiMer Medical MN 1000 External Stimulator
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Probiotics in the Treatment of Irritable Bowel Syndrome
Status: COMPLETED
Conditions: Irritable Bowel Syndrome
Interventions: DRUG: Lactol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Feasibility of Using the PulsePoint to Facilitate Overdose Education and Naloxone Distribution
Status: NOT_YET_RECRUITING
Conditions: Carrying Naloxone/Narcan on Their Person or in Their Vehicle|Being Trained to Respond to an Opioid Overdose
Interventions: BEHAVIORAL: Push messages (standard)|BEHAVIORAL: Push messages (customized)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Evaluation of the Clinical Effectiveness of Upper Gastrointestinal Endoscopy Reporting System
Status: NOT_YET_RECRUITING
Conditions: Endoscopy, Gastrointestinal|Artificial Intelligence
Interventions: DIAGNOSTIC_TEST: AI-based reporting system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Preference-based Tools for Smoking Cessation Among Disadvantaged Smokers, a Pragmatic Randomised Controlled Trial
Status: UNKNOWN
Conditions: Smoking|Smoking Cessation
Interventions: OTHER: The STOP intervention|OTHER: Standard Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Multiple Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Romosozumab (AMG 785)
Status: COMPLETED
Conditions: Postmenopausal|Osteopenia
Interventions: DRUG: Romosozumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Closed-loop Control of Glucose Levels (Artificial Pancreas) for 24 Hours in Adults With Type 2 Diabetes Under Intensive Insulin Therapy
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: OTHER: 24-hour intervention with multiple daily injections|OTHER: 24-hour intervention with closed-loop strategy|DRUG: Insulin|DEVICE: Insulin pump Accu-Chek Combo|DEVICE: Dexcom G4 Platinum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: What After the First Propess
Status: TERMINATED
Conditions: Induction of Labor
Interventions: DRUG: 10 mg Dinoprostone; CTS, UK|DRUG: 3 mg Dinoprostone vaginal tablet; Pfizer, UK|DRUG: Aquacryl hydrogel rod; HPSRx Enterprises, USA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Electrophysiological and Neuroimaging Correlates of the Effect of Zolpidem in Patients With Focal Dystonia
Status: COMPLETED
Conditions: Focal Dystonia
Interventions: DRUG: Zolpidem|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: High-Sensitivity Troponin T Plasma Levels in Patients With Aortic Stenosis (Tyrolean Aortic Stenosis Study-2)
Status: RECRUITING
Conditions: Aortic Stenosis|Heart Failure|Syncope|Angina Pectoris
Interventions: PROCEDURE: Aortic Valve Intervention (surgical or transcatheter)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of Pulpotomy Using Two Different Agents in Mature Anterior Teeth With Pulpitis
Status: NOT_YET_RECRUITING
Conditions: Pulpitis
Interventions: PROCEDURE: premixed Bioceramic NeoPUTTY®|PROCEDURE: Biodentine™|PROCEDURE: Root canal treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Multiple Dose Study of ABT-555 in Subjects With Relapsing Forms of Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DRUG: ABT-555|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Graceful Lifestyle Changes Study for PCOS and Infertility
Status: UNKNOWN
Conditions: Polycystic Ovary Syndrome|Infertility
Interventions: BEHAVIORAL: Graceful Lifestyle Changes|DIETARY_SUPPLEMENT: Myo-inositol|DRUG: Letrozole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adrenal Artery Ablation Treats Primary Aldosteronism
Status: COMPLETED
Conditions: Primary Aldosteronism|Hypertension
Interventions: PROCEDURE: Endovascular chemical Ablation of Adrenal Gland
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transforaminal Epidural Steroid Injection to Treat Hemiplegic Shoulder Pain
Status: UNKNOWN
Conditions: Hemiplegic Shoulder Pain
Interventions: PROCEDURE: transforaminal dexamethasone injection|PROCEDURE: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PArtial REbreathing for Migraine With Aura 1
Status: RECRUITING
Conditions: Migraine With Aura
Interventions: DEVICE: Partial Rebreathing Device|DEVICE: Sham breathing device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Suture Fixation Versus Tension Band Wiring of Simple Displaced Olecranon Fractures
Status: UNKNOWN
Conditions: Olecranon Fracture
Interventions: PROCEDURE: Suture fixation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fasting on Newly Diagnosed Breast Cancer
Status: TERMINATED
Conditions: HER2-positive Breast Cancer
Interventions: DRUG: Doxorubicin|DRUG: cyclophosphamide|DRUG: paclitaxel|DRUG: docetaxel|DRUG: Trastuzumab|DRUG: Pertuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Quantificational Enhancement Pattern Analysis Using a Novel Software "Vuebox" of Contrast-enhanced Harmonic Endoscopic Ultrasonography for Differential Diagnosis Between Adenomas and Cholesterol Polyps
Status: WITHDRAWN
Conditions: Gallbladder Polyp
Interventions: DEVICE: Quantitative analysis by using the new developed software program VueBox
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Exercise and Surgical Weight Loss on Polyneuropathy
Status: COMPLETED
Conditions: Polyneuropathies|Obesity|Bariatric Surgery Candidate
Interventions: OTHER: High Intensity Interval Training (HIIT)|OTHER: Routine Exercise|PROCEDURE: Bariatric surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Drug Interaction - Oral Contraceptive
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Ortho Tri-Cyclen LO|DRUG: Ortho Cyclen|DRUG: Ortho Cyclen + Efavirenz|DRUG: Ortho Cyclen
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Influence of Premedication Protocols for Neonatal Endotracheal Intubation on Cerebral Oxygenation
Status: COMPLETED
Conditions: Newborn|Preterm|Intubation
Interventions: DRUG: Atropine, Fentanyl, Mivacurium|DRUG: Atropine, Fentanyl, Mivacurium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hypertonic Saline Solution in Heart Failure
Status: COMPLETED
Conditions: Heart Failure|Renal Failure|Hyponatremia
Interventions: DRUG: NaCl 7,5% (Hypertonic Saline Solution)|DRUG: NaCl 0,9%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of a Novel Nutritional Product on Nutrient Gaps and Gut Health in Adults With Occasional Gastrointestinal Issues
Status: RECRUITING
Conditions: Gastrointestinal Microbiome|Nutrition, Healthy|Exercise
Interventions: DIETARY_SUPPLEMENT: AG1 - Nutritional Supplement|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: The Effect of the Consumption of 4 Botanical Extracts on Immunity in Healthy Adults (B-4-Immune)
Status: UNKNOWN
Conditions: Healthy Subject|Immunity
Interventions: DIETARY_SUPPLEMENT: Botanical extract
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION