pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Randomized, Active-controlled, Parallel, Open-label, Multicenter, Phase 4 Study to Compare the Efficacy and Safety of Pregabalin Sustained Release Tablet and Pregabalin Immediate Release Capsule in Type II Diabetic Patients With Peripheral Neuropathic Pain
Status: COMPLETED
Conditions: Neuropathic Pain|Diabetes Mellitus, Type 2
Interventions: DRUG: pregabalin sustained release tablet|DRUG: pregabalin immediate release capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study in Healthy Men to Test Whether Four Capsules of 25 mg Nintedanib Are Taken up in the Body in the Same Way as One 100 mg Capsule
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: nintedanib 25 mg|DRUG: nintedanib 100 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Interest of Bone Substitute Material in Immediate Complete Denture
Status: UNKNOWN
Conditions: Alveolar Bone Loss|Denture Complete Immediate|Bone Substitute|Replacement Material|Bone
Interventions: DEVICE: Conventional protocol|DEVICE: Bone substitute material group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dapagliflozin in STEMI Randomized Clinical Trial
Status: NOT_YET_RECRUITING
Conditions: ST Elevation Myocardial Infarction|Myocardial Infarction
Interventions: DRUG: Dapagliflozin 10mg Tab|DIAGNOSTIC_TEST: CMR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Varenicline (Chantix) and Bupropion (Zyban) on Smoking Lapse Behavior
Status: COMPLETED
Conditions: Smoking Lapse Behavior
Interventions: DRUG: varenicline|DRUG: bupropion|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Atrial Functional Mitral Regurgitation Response In Mitral Loop Cerclage Annuloplasty (AFRICA Study)
Status: COMPLETED
Conditions: Atrial Functional Mitral Regurgitation|Heart Failure
Interventions: DEVICE: Mitral Loop Cerclage Annuloplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pancreatic Carcinoma: Chemoradiation Compared With Chemotherapy Alone After Induction Chemotherapy
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DRUG: Induction chemotherapy with gemcitabine or FOLFIRINOX|RADIATION: Radiotherapy, 28 x 1.8 Gy|DRUG: Chemotherapy, gemcitabine|DRUG: Chemotherapy with gemcitabine or FOLFIRINOX according to induction chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Brolucizumab 6mg in a Treat and Extend Regimen in Patients With Neovascular Age-Related Macular Degeneration (nAMD) With Prior Anti-VEGF Exposure (PEREGRINE)
Status: WITHDRAWN
Conditions: Age-related Macular Degeneration (AMD)
Interventions: DRUG: brolucizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Non-invasive Vagus Nerve Stimulation on Cognitive Functions in Diabetic Polyneuropathy Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Diabetic Peripheral Neuropathy
Interventions: OTHER: A computer based cognitive rehabilitation program (Rehacom system)|DEVICE: Vagus nerve stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effects of Ultrasound-guide Hypertonic Dextrose Injection for Chronic Subacromial Bursitis
Status: UNKNOWN
Conditions: Chronic Shoulder Pain
Interventions: DRUG: hypertonic dextrose water|DRUG: Triamcinolone Acetonide.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Reduced Infant Response to a Routine Care Procedure After Glucose 25% Analgesia in Comparison to Materna RTF Stage 1
Status: UNKNOWN
Conditions: Infant, Newborn, Diseases
Interventions: DRUG: Glucose 25%|DIETARY_SUPPLEMENT: Materna RTF Stage 1|OTHER: Water for Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose:
Clinical trial: The Effect of Erector Spinae Plane Block on Quality of Recovery and Postoperative Analgesia After Inguinal Hernia Repair
Status: COMPLETED
Conditions: Postoperative Pain|Inguinal Hernia|Acute Pain
Interventions: PROCEDURE: ESP Block|OTHER: Global Quality of Recovery-15 score|OTHER: Standard Pain Followup and Monitorization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: T3 Versus T4 Sympathicotomy for Treatment of Primary Palmar Hyperhidrosis
Status: COMPLETED
Conditions: Compensatory Hyperhidrosis|Recurrence
Interventions: PROCEDURE: t3 sympathicotomy|PROCEDURE: t4 symapthicotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: PET/MR for Prostate Cancer Restaging: a Phase II Prospective Monocentric Study
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: 68Ga-PSMA|DRUG: 68Ga-RM2
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effects of Qigong, Tai Chi and Yoga Practice in Older Adults
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: YiRen Qi gong|OTHER: Tai Chi|OTHER: Hatha yoga
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Monteris AutoLITT™ FIM Safety Trial for Recurrent/Progressive Brain Tumors
Status: COMPLETED
Conditions: Brain Tumor|Brain Tumor, Recurrent|Brain Neoplasm|Brain Cancer|Glioblastoma Multiforme|Recurrent Glioblastoma Multiforme
Interventions: DEVICE: AutoLITT system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low Level Laser Therapy Applied in Orthodontic Tooth Movement
Status: RECRUITING
Conditions: Orthodontic Appliance Complication
Interventions: DEVICE: Low Level Laser Therapy|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Effect of Lidocaine Transdermal Patch as Add-On Therapy in Treatment of Oxaliplatin Induced Peripheral Neuropathy in Colorectal Cancer Patients
Status: RECRUITING
Conditions: Oxaliplatin Induced Peripheral Neuropathy in Cancer Patients
Interventions: DRUG: lidocaine transdermal patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Thoracic Epidural Analgesia With Bilateral Erector Spinae Plane Block in Radical Cystectomy Surgery
Status: COMPLETED
Conditions: Post Operative Pain
Interventions: PROCEDURE: bilateral Erector spine block,A dose of 30 ml 0.125% Bupivacaine will be injected.|PROCEDURE: Thoracic epidural analgesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Conquer Fear SUPPORT Intervention in Supporting Patients With Stage III-IV Lung or Gynecologic Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Lung Carcinoma|Malignant Female Reproductive System Neoplasm|Stage III Lung Cancer AJCC v8|Stage IIIA Lung Cancer AJCC v8|Stage IIIB Lung Cancer AJCC v8|Stage IIIC Lung Cancer AJCC v8|Stage IV Lung Cancer AJCC v8
Interventions: BEHAVIORAL: Psychosocial Care Conquer Fear Support intervention (psychoeducation, attention training, worry management, and detached mindfulness components)|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: To Evaluate the Effect of Different Doses of SAR156597 Given to Patients With Idiopathic Pulmonary Fibrosis (IPF)
Status: COMPLETED
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: DRUG: SAR156597|DRUG: Placebo (for SAR156597)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: NGS-MRD Assessment of Combination Immunotherapies Targeting T-ALL
Status: RECRUITING
Conditions: T-Cell Acute Lymphoblastic Leukemia
Interventions: BIOLOGICAL: Antigen-specific T cells CAR-T/CTL and DCvac
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose-ranging Study to Assess the Efficacy and Safety of Ciclesonide HFA Nasal Aerosol in Adult and Adolescent Patients 12 Years and Older With Seasonal Allergic Rhinitis (SAR) (BY9010/M1-602)
Status: COMPLETED
Conditions: Rhinitis, Allergic, Seasonal
Interventions: DRUG: Ciclesonide HFA|DRUG: Ciclesonide HFA|DRUG: Ciclesonide HFA|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Therapeutic Effect of Co-administration of Pentoxifylline and Zinc in Men With Idiopathic Asthenozoospermia
Status: UNKNOWN
Conditions: Men Infertility
Interventions: DRUG: Zinc Sulfate 220 mg Capsules|DRUG: Pentoxifylline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Hypofractionated Irradiation At Regional Nodal Area for Breast Cancer Vs Existed Standard Treatment
Status: RECRUITING
Conditions: Breast Cancer
Interventions: RADIATION: Hypofractionated radiotherapy|RADIATION: Conventional radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Treadmill Training Program Augmented by Virtual Reality to Decrease Fall Risk in Older Adults
Status: COMPLETED
Conditions: Elderly Adults|Parkinson|Mild Cognitive Disorder
Interventions: OTHER: TT+VR|OTHER: TT alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tagraxofusp (SL-401) in Patients With CMML or MF
Status: COMPLETED
Conditions: Myelofibrosis|Chronic Myelomonocytic Leukemia
Interventions: DRUG: SL-401
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Levofloxacin In The Treatment Of Children With Recurrent And/or Persistent Acute Otitis Media
Status: COMPLETED
Conditions: Otitis Media
Interventions: DRUG: levofloxacin; amoxicillin/clavulanate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety and Efficacy of Treatment With NLM-001 and Standard Chemotherapy Plus Zalifrelimab in Patients With Advanced Pancreatic Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Pancreatic Ductal Adenocarcinoma
Interventions: DRUG: Gemcitabine|DRUG: Nab paclitaxel|DRUG: NLM-001|DRUG: Zalifrelimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Azithromycin Treatment of Hospitalized Children With Asthmatic Symptoms
Status: RECRUITING
Conditions: Childhood Asthma With Acute Exacerbation
Interventions: DRUG: Azithromycin Oral Liquid Product|OTHER: Placebo mixture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: 9 mg Budesonide Once Daily (OD) Versus 3 mg Budesonide Three Times Daily (TID) in Active Crohn's Disease
Status: COMPLETED
Conditions: Crohn´s Disease
Interventions: DRUG: budesonide|DRUG: budesonide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Efficacy of Ovule vs Tablet
Status: COMPLETED
Conditions: Clotrimazole|Ovulen|Vulvovaginal Candidiasis
Interventions: DRUG: Clotrimazole, vaginal ovule|DRUG: Clotrimazole, vaginal tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Improving Adherence to Web-Based Cessation Programs: A Social Network Approach
Status: COMPLETED
Conditions: Smoking Cessation
Interventions: BEHAVIORAL: WEB|BEHAVIORAL: Social Network|BEHAVIORAL: Nicotine Replacement Therapy (NRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Behavioral Intervention to Decrease Vomiting and Improve Weight Loss in Post-Operative Laparoscopic Adjustable Gastric Banding (LAGB) Patients
Status: SUSPENDED
Conditions: Bariatric Surgery Complications
Interventions: BEHAVIORAL: behavioral intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Two Herbal Dietary Supplements on Lipid Metabolism in Moderate Hypercholesterolemia and Hypertriglyceridemia
Status: COMPLETED
Conditions: Hypercholesterolemia|Hypertriglyceridemia
Interventions: DIETARY_SUPPLEMENT: VAL070-A|DIETARY_SUPPLEMENT: VAL070-B|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Tolerability Study of GSK2586184 in Patients With Moderate to Severely Active Ulcerative Colitis.
Status: TERMINATED
Conditions: Colitis, Ulcerative
Interventions: DRUG: GSK2586184 400mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Enhancing Triadic Communication About Cognition for Older Adults With Alzheimer's Disease or Related Dementias Facing a Cancer Management Decision
Status: RECRUITING
Conditions: Cancer|Dementia
Interventions: BEHAVIORAL: COACH-Cog
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of a Nasal Bolus Allergen Challenge on Inflammatory Markers
Status: COMPLETED
Conditions: Seasonal Allergic Rhinitis
Interventions: PROCEDURE: Intra-nasal allergen challenge with Phleum pratense.|PROCEDURE: Collection of nasal effluent using filter paper.|PROCEDURE: Measurement of nasal congestion using acoustic rhinometry.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy and Bevacizumab With or Without PRI-724 in Treating Patients With Newly Diagnosed Metastatic Colorectal Cancer
Status: WITHDRAWN
Conditions: Colorectal Adenocarcinoma|Stage IVA Colorectal Cancer|Stage IVB Colorectal Cancer
Interventions: DRUG: CBP/beta-catenin Antagonist PRI-724|BIOLOGICAL: Bevacizumab|DRUG: Leucovorin Calcium|DRUG: Oxaliplatin|DRUG: Fluorouracil|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of an Abstinence-Only HIV Risk-Reduction Intervention for Young African-American Adolescents
Status: COMPLETED
Conditions: HIV Infections|Sexually Transmitted Diseases
Interventions: BEHAVIORAL: Abstinence-only HIV/STD risk-reduction intervention|BEHAVIORAL: Safer-sex-only HIV/STD risk-reduction intervention|BEHAVIORAL: Long comprehensive HIV/STD risk-reduction intervention|BEHAVIORAL: Short comprehensive HIV/STD risk-reduction intervention|BEHAVIORAL: Health promotion control intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Targeting Lower Arterial Oxygen Saturations on the Development of Control of Breathing in Very Preterm Infants
Status: COMPLETED
Conditions: Development of Control of Breathing
Interventions: OTHER: Oxygen saturation range|OTHER: Oxygen saturation range
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study Evaluating the Efficacy and Safety of Adding Symlin® to Lantus® (Insulin Glargine) in Subjects With Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: pramlintide acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Cardio-protective Effect of Metformin in Patients Undergoing PCI
Status: ACTIVE_NOT_RECRUITING
Conditions: Elective Percutaneous Coronary Intervention|Ischemic Reperfusion Injury
Interventions: DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Non Culprit Functional Evaluation With 3D Angio QFR in STEMI PCI Procedure
Status: UNKNOWN
Conditions: STEMI - ST Elevation Myocardial Infarction|Percutaneous Coronary Intervention|Coronary Artery Disease
Interventions: OTHER: QFR measurement by dedicated workstation on xrays angio selected runs
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Oral Administration of Polyethylene Glycol (PEG) for 6 Months in Chronically Constipated Autistic Children
Status: COMPLETED
Conditions: Autistic Spectrum Disorder|Constipation
Interventions: DIETARY_SUPPLEMENT: Gut mobilization
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Subcutaneous Adipose Tissue in the Thighs Using High Intensity Focused Ultrasound
Status: COMPLETED
Conditions: Treatment of Adipose Tissue in the Thighs
Interventions: DEVICE: Liposonix System (Model 2)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Absorption and Muscle-stimulating Effect of Hydrolyzed and Minced Beef
Status: UNKNOWN
Conditions: Meat Protein Supplements|Protein Absorption and Amino Acid Availability|Muscle Protein Synthesis
Interventions: DIETARY_SUPPLEMENT: Minced beef|DIETARY_SUPPLEMENT: Hydrolyzed beef
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Comparison Between Different Anaesthesia Techniques Protecting Renal Function in Children Undergoing Radicle Nephrectomy
Status: COMPLETED
Conditions: Renal Injury|Child, Only
Interventions: DRUG: Dexmedetomidine|DRUG: bupivacaine|DRUG: normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Effect of Neem and NaOCl on Postoperative Pain and Amount of Endotoxins
Status: UNKNOWN
Conditions: Pain|Postoperative Pain|Postoperative Complications|Necrosis|Pathologic Processes
Interventions: DRUG: Neem|DRUG: 2.5% sodium hypochlorite
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of L. Reuteri in Infantile Colic 2017
Status: UNKNOWN
Conditions: Infantile Colic
Interventions: DIETARY_SUPPLEMENT: L. reuteri DSM 17938 in drops|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Short Stitch Versus Traditional Suture for the Prevention of Incisional Hernia After Open Hepatectomy
Status: RECRUITING
Conditions: Liver and Intrahepatic Bile Duct Neoplasm|Metastatic Malignant Neoplasm in the Liver|Primary Malignant Liver Neoplasm
Interventions: OTHER: Quality-of-Life Assessment|PROCEDURE: Surgical Procedure|PROCEDURE: Surgical Procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effects of a Polyphenol-enriched Fruit Drink on Metabolic Health
Status: COMPLETED
Conditions: Healthy Men and Women
Interventions: DIETARY_SUPPLEMENT: Polyphenol-enriched fruit-based drink - low|DIETARY_SUPPLEMENT: Polyphenol-enriched fruit-based drink - medium|DIETARY_SUPPLEMENT: Polyphenol-enriched fruit-based drink - high|DIETARY_SUPPLEMENT: Very low polyphenol fruit based drink (control)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study to Evaluate Safety, PK and PD of Single and Multiple Ascending Doses of EP-7041 in Healthy Subjects
Status: COMPLETED
Conditions: Arthroplasty, Replacement, Knee
Interventions: DRUG: EP=7041|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study With High Dose PURETHAL Mites in Allergic Rhinitis/Rhinoconjunctivitis Patients
Status: COMPLETED
Conditions: Allergic Rhinitis|Allergic Rhinoconjunctivitis
Interventions: DRUG: PURETHAL Mites 20,000 AUeq/ml|DRUG: PURETHAL Mites 20,000 AUeq/ml|DRUG: PURETHAL Mites 20,000 AUeq/ml
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Effects of Oxytocin on the Functional Architecture of the Brain Before and After Prolonged Naturalistic Fear Induction
Status: RECRUITING
Conditions: Healthy
Interventions: DRUG: intranasal Oxytocin(24IU)|DRUG: intranasal Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Hyperbaric Oxygen Therapy in Chronic Stable Brain Injury
Status: COMPLETED
Conditions: Brain Injury|Sequelae|Stroke|Anoxia|Trauma
Interventions: PROCEDURE: Hyperbaric oxygen therapy (HBO2)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Different Luteal Phase Support Methods in Patients With Poor Ovarian Response
Status: UNKNOWN
Conditions: Infertility
Interventions: DRUG: Choriomon® injection|DRUG: Choriomon® injection+Endometrin ®|DRUG: Endometrin ® vaginal tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Double-Blind, Placebo Controlled, Single, Escalating Dose Study to Evaluate the Preliminary Pharmacokinetics, Safety and Tolerability of LNK-754 in Healthy Elderly Volunteers
Status: COMPLETED
Conditions: Healthy Elderly Volunteers
Interventions: DRUG: LNK-754
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE|Primary Purpose:
Clinical trial: Accelerated Aging in Middle-Aged Men With Sleep-disordered Breathing.
Status: COMPLETED
Conditions: Obstructive Sleep Apnea
Interventions: OTHER: Polysomnography , blood collection, bone densitometry and Functional respiratory explorations
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Trial Investigating the Pharmacokinetic and Pharmacodynamic Properties of Faster-acting Insulin Aspart in Subjects With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: Faster-acting insulin aspart|DRUG: Insulin Aspart
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: 16-week Efficacy and 2-year Safety, Tolerability and Efficacy of Secukinumab in Participants With Active Ankylosing Spondylitis
Status: COMPLETED
Conditions: Spondylitis, Ankylosing
Interventions: BIOLOGICAL: Secukinumab|BIOLOGICAL: Secukinumab|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Remote Support for Cochlear Implant Recipients: Evaluation of the HearCare MED-EL App
Status: NOT_YET_RECRUITING
Conditions: Hearing Loss, Sensorineural|Cochlear Implant
Interventions: DEVICE: HearCare MED-EL App
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Evaluation of The Efficacy and Safety of Tixel Treatment for the Treatment of Facial and/or Scalp Actinic Keratoses
Status: COMPLETED
Conditions: Actinic Keratoses
Interventions: DEVICE: Tixel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Research Study to Compare Semaglutide Tablets With Empagliflozin Tablets Taken Once Daily in People With Type 2 Diabetes and Obesity
Status: WITHDRAWN
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Semaglutide|DRUG: Empagliflozin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Relative Bioavailability, Pharmacokinetics, Safety and Tolerability of BIIL 284 BS in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BIIL 284 BS tablet C|DRUG: BIIL 284 BS tablet D|DRUG: BIIL 284 BS WIF tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Placebo Controlled Study of Triamcinolone Acetonide Extended Release Injection for Thumb (CMC) Osteoarthritis
Status: RECRUITING
Conditions: Carpometacarpal (CMC) Osteoarthritis
Interventions: DRUG: Triamcinolone Acetonide extended release suspension
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Non-inferiority Between Manzanilla Sophia® and Meticel Ofteno® 0.5% for Providing a Soothing Sensation to the Eyes.
Status: NOT_YET_RECRUITING
Conditions: Eye Strain|Eye Strain of Both Eyes
Interventions: DRUG: Manzanilla Sophia®|DRUG: Meticel Ofteno®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Krypton-Argon Regression of Neovascularization Study (KARNS)
Status: COMPLETED
Conditions: Diabetic Retinopathy|Retinal Neovascularization|Diabetes Mellitus
Interventions: PROCEDURE: Blue-Green Argon Laser Treatment|PROCEDURE: Red Krypton Laser Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Prasugrel 5 mg vs. Ticagrelor 60 mg in CHIP (E5TION)
Status: UNKNOWN
Conditions: Coronary Artery Disease
Interventions: DRUG: Prasugrel 5mg|DRUG: Ticagrelor 60mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Questionnaire to Assess Gastrointestinal Symptoms of Oral Iron.
Status: COMPLETED
Conditions: Anemia|Constipation|Diarrhea|Abdominal Pain|Heartburn|Side Effect
Interventions: DIETARY_SUPPLEMENT: ferrous sulfate|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Time Restricted Feeding on Impaired Glucose Regulation(TRIG Trial)
Status: RECRUITING
Conditions: Time-Restricted Feeding|Impaired Glucose Regulation|Overweight/Obese
Interventions: BEHAVIORAL: Time Restricted Feeding(TRF)|BEHAVIORAL: Reduced Calorie Diet (RCD)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Erivedge (Vismodegib) in the Treatment of Pediatric Patients With Refractory Pontine Glioma
Status: TERMINATED
Conditions: Pontine Glioma
Interventions: DRUG: Vismodegib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate if AC-084 is Safe, Its Fate in the Body as Well as Its Potential Effects on the Body in Healthy Subjects
Status: TERMINATED
Conditions: Healthy Subjects
Interventions: DRUG: AC-084|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Comparative Microbial Analysis of Cystitis in Non-muscle-invasive Bladder Cancer Patients Using Vikor Scientific Urine-ID Testing Menu (IDTM) and Standard Laboratory Culture
Status: UNKNOWN
Conditions: Urinary Tract Infections|Bladder Cancer
Interventions: DIAGNOSTIC_TEST: Vikor Scientific Urine-IDTM
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Systemic Oxaliplatin or Intra-arterial Chemotherapy Combined With LV5FU2 +/- Irinotecan and an Target Therapy in First Line Treatment of Metastatic Colorectal Cancer Restricted to the Liver
Status: RECRUITING
Conditions: Colorectal Neoplasms
Interventions: DRUG: Oxaliplatin intravenous|DRUG: 5 FU bolus|DRUG: Folinic acid|DRUG: Oxaliplatin intra-arteriel|DRUG: Panitumumab|DRUG: Bevacizumab|DRUG: 5 FU continuous|DRUG: Irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combined O-(2-[18F]Fluoroethyl)-L-tyrosine (FET) Positron Emission Tomography (PET) and Simultaneous Magnetic Resonance Imaging (MRI) Follow-up in Re-irradiated Recurrent Glioblastoma Patients
Status: UNKNOWN
Conditions: Glioblastoma|Nervous System Neoplasms|Central Nervous System Neoplasms|Astrocytoma|Glioma|Neoplasms, Neuroepithelial|Neuroectodermal Tumors|Neoplasms by Histologic Type|Neoplasms, Nerve Tissue
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Electrical Stimulation of the Peripheral Vestibular System in Order to Develop a Vestibular Implant
Status: UNKNOWN
Conditions: Vestibular Disorder|Bilateral Vestibulopathy|Bilateral Vestibular Loss
Interventions: PROCEDURE: Electrical stimulation of the vestibular system|PROCEDURE: Electrical stimulation of the auditory system|DIAGNOSTIC_TEST: Bilateral vestibulopathy Patients (BV)|DIAGNOSTIC_TEST: Unilateral vestibulopathy Patients (UV)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Use of Specific Genetic Alteration s of Tumoral Cells Identified by the Next Generation Sequencing Techniques (NGS) to Follow Peripheral Samples of Children With Metastatic and/or High Risk Solid Tumor - NGSKids
Status: COMPLETED
Conditions: Metastatic and/or High Risk Solid Tumor of Children
Interventions: BIOLOGICAL: Tumoral specific genetic alterations|BIOLOGICAL: Tumoral specific genetic alterations
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Importance of Ghrelin for Glucose Metabolism After Sleeve Gastrectomy
Status: COMPLETED
Conditions: Bariatric Surgery Candidate|Glucose Metabolism Disorders
Interventions: OTHER: Ghrelin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of a PPAR-Alpha Agonist on the Age Related Changes in Myocardial Metabolism and Mechanical Function
Status: UNKNOWN
Conditions: Cardiovascular Diseases
Interventions: DRUG: fenofibrate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Interest of a Dose Decrease for Radiotherapy Associated With Chemotherapy for Treatment of Standard Risk Adult Medulloblastomas
Status: UNKNOWN
Conditions: Medulloblastoma
Interventions: DRUG: carboplatine|DRUG: Etoposide|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Self-Monitoring of Blood Glucose Study#1: The Ability of People With Diabetes to Use OneTouch(R) Ultrasmart(tm)
Status: COMPLETED
Conditions: Diabetes
Interventions: DEVICE: OneTouch(r) UltraSmart(r)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Investigating Brain Insulin Resistance In Alzheimer Disease With IntraNasal Insulin : A Multimodal Neuroimaging Study
Status: NOT_YET_RECRUITING
Conditions: Alzheimer Disease|Mild Cognitive Impairment
Interventions: DRUG: Insulin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Impact of Telemonitoring to Improve Adherence in Continuous Positive Airway Pressure (CPAP)-Treated Patients
Status: COMPLETED
Conditions: Obstructive Sleep Apnea
Interventions: DEVICE: T4PTelemonitoring|DEVICE: CPAP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating the Effect of Desvenlafaxine on the Pharmacokinetics of Midazolam
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: Desvenlafaxine Succinate Sustained Release|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Severe Psoriatic Arthritis - Early intervEntion to Control Disease: the SPEED Trial
Status: RECRUITING
Conditions: Psoriatic Arthritis
Interventions: DRUG: Methotrexate|DRUG: Sulfasalazine|DRUG: Leflunomide|DRUG: Adalimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Direct Anterior Approach (DAA) for Total Hip Arthroplasty (THA): Capsular Resection Versus Capsular Flap Retention
Status: COMPLETED
Conditions: Coxarthritis
Interventions: PROCEDURE: Capsular resection|PROCEDURE: Capsular retention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Pulmonary Mechanics During Minimally Invasive Repair of Pectus Excavatum
Status: UNKNOWN
Conditions: Pectus Excavatum
Interventions: DRUG: Desflurane|DRUG: Sevoflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The ESTxENDS Trial- Substudy on the Effects of Using Electronic Nicotine Delivery Systems (ENDS) on Sleep Quality.
Status: COMPLETED
Conditions: Smoking Cessation|Sleep
Interventions: OTHER: ENDS (vaporizer/e-cig) and smoking cessation counseling|OTHER: Smoking cessation counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: the Peri-implant Tissue Changes Around Implants in the Esthetic Zone Using Demineralized Dentin Graft vs Xenograft
Status: RECRUITING
Conditions: Implant Site Reaction
Interventions: BIOLOGICAL: Partially demineralized dentin graft covered with a collagen membrane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Non-Pedicled Buccal Fat Pad Graft in the Treatment of Gingival Recessions
Status: COMPLETED
Conditions: Gingival Recession
Interventions: PROCEDURE: Treatment with subepithelial connective tissue graft (SCTG)|PROCEDURE: Treatment with non-pedicled buccal fat pad graft (BFPG)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Ribociclib and Everolimus in HGG and DIPG
Status: NOT_YET_RECRUITING
Conditions: High Grade Glioma|Diffuse Intrinsic Pontine Glioma|Anaplastic Astrocytoma|Glioblastoma|Glioblastoma Multiforme|Diffuse Midline Glioma, H3 K27M-Mutant|Metastatic Brain Tumor|WHO Grade III Glioma|WHO Grade IV Glioma
Interventions: DRUG: Ribociclib|DRUG: Everolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Nurse-led Motivational Interviewing Based on the Trans-theoretical Model
Status: COMPLETED
Conditions: Older Adult|Motivational Interviewing|Physical Activity|Nursing Caries
Interventions: BEHAVIORAL: Intervention motivational interview group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Octreotide in Severe Polycystic Liver Disease
Status: COMPLETED
Conditions: Polycystic Kidney, Autosomal Dominant|Polycystic Liver Disease|Hepatomegaly|Liver Diseases|Kidney, Polycystic|Abdominal Pain
Interventions: DRUG: Octreotide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of External Genital Warts With Cryotherapy and Sinecatechins 15% Ointment
Status: COMPLETED
Conditions: External Genital Warts
Interventions: DRUG: Sinecatechins 15% Ointment|DRUG: Cryotherapy alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Extracorporeal Shock Wave Therapy, Ultrasound and Phonophoresis Treatments in Lateral Epicondylitis
Status: COMPLETED
Conditions: Lateral Epicondylitis
Interventions: DEVICE: ESWT|DEVICE: Phonophoresis|DEVICE: Ultrasound|OTHER: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Types of Family Therapy in the Treatment of Adolescent Anorexia Nervosa
Status: COMPLETED
Conditions: Anorexia Nervosa
Interventions: BEHAVIORAL: Family Behavior Therapy|BEHAVIORAL: Systems Family Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Preoperative Transarterial Chemoembolization for Resectable HCC With Portal Venous Invasion
Status: COMPLETED
Conditions: Resectable Hepatocellular Carcinoma With Portal Vein Tumor Thrombus
Interventions: PROCEDURE: Preoprative TACE|PROCEDURE: Liver resection plus Thrombectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multicenter, Open-label Phase 3 Study: Ambulatory Blood Pressure Monitoring in Adult Patients With Chronic Spontaneous Urticaria Inadequately Controlled by H1-antihistamines Treated With Remibrutinib up to 12 Weeks.
Status: COMPLETED
Conditions: Chronic Spontaneous Urticaria
Interventions: DRUG: LOU064
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Periodontitis Using Er:YAG Laser vs. Conventional Treatment Modalities
Status: COMPLETED
Conditions: Chronic Periodontitis
Interventions: PROCEDURE: Er: YAG Laser|PROCEDURE: Conventional treatment 1(ultrasonic and manual means)|PROCEDURE: Conventional treatment 2 (ultrasonic and manual means)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare the Effect of Transipeg 2.95 g or Forlax Junior 4 g in Children With Constipation
Status: COMPLETED
Conditions: Constipation
Interventions: DRUG: Macrogol (Transipeg, BAY81-8430)|DRUG: Macrogol (Forlax)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: HVIP Outcomes and Stakeholder Insights
Status: NOT_YET_RECRUITING
Conditions: Firearm Injury|Violence, Physical
Interventions: BEHAVIORAL: Turning the Tide Violence Intervention Program (hospital violence intervention program)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Transcutaneous Electrical Acupoint Stimulation for the Treatment of ADHD
Status: COMPLETED
Conditions: ADHD
Interventions: DEVICE: Transcutaneous Electrical Acupoint Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Therapeutic Interventions For Pain Induced By Vincristine Treatment For Childhood Acute Lymphoblastic Leukemia (ALL)
Status: COMPLETED
Conditions: Acute Lymphoblastic Leukemia|Neuropathy|Neuropathic Pain
Interventions: DRUG: gabapentin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: BCMA-CD19 cCAR in Multiple Myeloma and Plasmacytoid Lymphoma
Status: UNKNOWN
Conditions: Multiple Myeloma in Relapse|Refractory Multiple Myeloma|Plasmacytoid; Lymphoma
Interventions: BIOLOGICAL: BCMA-CD19 cCAR T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Tool Placement in Pulmonary Nodule(s) Using a Robotic Navigational Bronchoscopy System
Status: ACTIVE_NOT_RECRUITING
Conditions: Lung Cancer
Interventions: DEVICE: Biopsy with the Robotic- Ion Endoluminal System with Adjunct Real-time Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Determine the Safety and Efficacy of Oligopin® on Metabolic Risk Factors in Subjects With Metabolic Syndrome
Status: UNKNOWN
Conditions: Metabolic Syndrome
Interventions: DIETARY_SUPPLEMENT: Oligopin®|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Tirzepatide Plus Intensive Lifestyle Therapy on Body Weight and Metabolic Health in Latinos With Obesity
Status: TERMINATED
Conditions: Obesity|Metabolic Disease
Interventions: BEHAVIORAL: Standard Care|BEHAVIORAL: Culturally-tailored dietary and behavioral intensive lifestyle intervention|DRUG: Placebo|DRUG: Tirzepatide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Small Interfering Ribonucleic Acid (RNA) Molecule (Cand5) to Treat Wet Age-Related Macular Degeneration
Status: COMPLETED
Conditions: Macular Degeneration
Interventions: DRUG: Bevasiranib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Recovery From Rocuronium 1.2 mg/kg Followed by Sugammadex (Org 25969) 16 mg/kg at 3 Minutes With Recovery From Succinylcholine 1.0 mg/kg (19.4.303)(P05946)(MK-8616-026)
Status: COMPLETED
Conditions: Anesthesia, General
Interventions: DRUG: Sugammadex|DRUG: Succinylcholine|DRUG: Rocuronium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PRophylactic Cerebral Irradiation or Active MAgnetic Resonance Imaging Surveillance in Small-cell Lung Cancer Patients (PRIMALung Study)
Status: RECRUITING
Conditions: Limited Stage Small Cell Lung Cancer|Extensive-stage Small-cell Lung Cancer
Interventions: RADIATION: Prophylactic cranial irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Experimental Medication BMS-986235 in Healthy Subjects
Status: COMPLETED
Conditions: Mediators of Inflammation
Interventions: DRUG: BMS-986235|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mind-Body Skills Groups for the Treatment of War Zone Stress in Military and Veteran Populations
Status: COMPLETED
Conditions: Stress Disorders, Post Traumatic|Brain Injuries|Depressive Disorder|Anxiety Disorders|Anger
Interventions: BEHAVIORAL: Mind-Body Skills Groups|OTHER: Standard Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Normalizing Blood Pressure on Cerebral Blood Flow in Hypotensive Individuals With Spinal Cord Injury
Status: COMPLETED
Conditions: Spinal Cord Injury|Autonomic Dysreflexia|Baroreceptor Integrity|Sympathetic Integrity|Vagal Integrity|Autonomic Integrity|Hypotensive|Cognitive Function|Cerebral Blood Flow|Blood Pressure
Interventions: DRUG: Midodrine Hydrochloride|DRUG: Pyridostigmine Bromide|DRUG: Mirabegron|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT