pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: The Learning Effects of Task-priority Strategy on Dual-task Weight Shifting and Brain Plasticity in Patients With Parkinson's Disease
Status: COMPLETED
Conditions: Postural and Suprapostural Performance During Dual Tasking in Patients With Parkinson's Disease
Interventions: BEHAVIORAL: Weight-shifting training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Blood Lipid-lowering Effect of Brown Alga Ecklonia Cava
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DIETARY_SUPPLEMENT: ECE (Ecklonia cava extract)|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Stem Cell Therapy in Patients With Severe Heart Failure & Undergoing Left Ventricular Assist Device Placement
Status: COMPLETED
Conditions: Heart Failure
Interventions: BIOLOGICAL: Intramyocardial Delivery of Bone Marrow Derived Mononuclear Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Sativex® for Pain Relief Due to Diabetic Neuropathy
Status: COMPLETED
Conditions: Pain|Diabetic Neuropathy
Interventions: DRUG: Sativex|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Treatment of Angiotensin Peptide (1-7) for COVID-19
Status: COMPLETED
Conditions: COVID-19
Interventions: BIOLOGICAL: Biological/Vaccine: Angiotensin peptide (1-7) derived plasma
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PENNVAX-B With or Without IL-12 or IL-15 as a DNA Vaccine for HIV Infection
Status: COMPLETED
Conditions: HIV Infection
Interventions: BIOLOGICAL: PENNVAX-B|BIOLOGICAL: GENEVAX IL-12-4532|BIOLOGICAL: PLACEBO|BIOLOGICAL: IL-15 adjuvant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Compare the Outcomes of Zone II Flexor Tendon Repair of the Hand Under General Anesthesia Versus WALANT
Status: COMPLETED
Conditions: Cut Flexor Hand|Walant|General Anesthesia
Interventions: PROCEDURE: surgery of zone II cut flexor repair
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Optical Defocus to Stimulate Eye Elongation in Hyperopia
Status: UNKNOWN
Conditions: Hyperopia|Refractive Error
Interventions: DEVICE: Simultaneous Vision Bifocal Soft Contact Lenses|DEVICE: Single Vision Soft Contact Lenses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Clinical and Biological Effect of ESWT With Combined PRP Therapy on Rotator Cuff Lesions
Status: UNKNOWN
Conditions: Rotator Cuff Lesions
Interventions: COMBINATION_PRODUCT: PPR group with ESWT|COMBINATION_PRODUCT: PPR group without ESWT|COMBINATION_PRODUCT: HA group with ESWT|COMBINATION_PRODUCT: HA group without ESWT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Neuroprotection and Natural History in Parkinson's Plus Syndromes (NNIPPS)
Status: TERMINATED
Conditions: Multiple System Atrophy|Progressive Supranuclear Palsy
Interventions: DRUG: Riluzole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: GnRH Antagonist Pre-treatment in the Early Follicular Phase for Resolution of a Baseline Functional Ovarian Cyst
Status: UNKNOWN
Conditions: IVF|Ovarian Cysts
Interventions: DRUG: Cetrorelix Acetate, Ganerelix Acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MicroRNAs as Bile-based Biomarkers in Pancreaticobiliary Cancers
Status: COMPLETED
Conditions: Pancreatic Cancer|Cholangiocarcinoma|Ampullary Cancer|Biliary Stricture|Gallstone Disease
Interventions: DIAGNOSTIC_TEST: Small RNA Sequencing and Validation of candidate miRNAs
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Placebo-Controlled Study Assessing Lateral Branch Radiofrequency Denervation for Sacroiliac (SI) Joint Pain
Status: COMPLETED
Conditions: Low Back Pain
Interventions: PROCEDURE: radiofrequency denervation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: The Effects of a Novel Nutritional Product on Nutrient Gaps and Gut Health in Active Adults
Status: RECRUITING
Conditions: Gastrointestinal Microbiome|Nutrition, Healthy|Exercise
Interventions: DIETARY_SUPPLEMENT: AG1 - Nutritional Supplement|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Text-based Reminders to Promote COVID-19 Vaccinations
Status: COMPLETED
Conditions: Covid19, Vaccines
Interventions: BEHAVIORAL: Self-benefit|BEHAVIORAL: Prosocial-benefit|BEHAVIORAL: Early access|BEHAVIORAL: Fresh start
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Revlite Laser System Compared to the Candela Alex TriVantage System Refractory Mixed Type Melasma
Status: TERMINATED
Conditions: Melasma
Interventions: DEVICE: Revlite Q switched Nd:YAG|DEVICE: Trivantage Q switched Nd: YAG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Effect of White Potatoes on Glycemic Response and Satiety in Older Adults
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: White bread|OTHER: Baked potato with skin|OTHER: Mashed potatoes|OTHER: Fried French fries|OTHER: Meal skipping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Different Application Strategies When Using Futurabond Universal in Class V Cavities
Status: ACTIVE_NOT_RECRUITING
Conditions: Dental Restoration Failure of Marginal Integrity
Interventions: OTHER: Self-Etching Application Strategy|OTHER: Enamel Etching Application Strategy|OTHER: Etch&Rinse Dry Application Strategy|OTHER: Etch&Rinse Wet Application Strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Air Optix Daily Wear Contact Lenses
Status: COMPLETED
Conditions: Refractive Errors
Interventions: DEVICE: Lotrafilcon B spherical soft contact lenses|DEVICE: Lotrafilcon B spherical soft contact lenses with comfort additive|DEVICE: Lotrafilcon B toric soft contact lenses with comfort additive|DEVICE: Comfilcon A spherical soft contact lenses|DEVICE: Comfilcon A toric soft contact lenses
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Trial of Image-Guided Cochlear Implant Programming Versus Standard of Care
Status: WITHDRAWN
Conditions: Cochlear Implant
Interventions: OTHER: Standard of Care|OTHER: Image-Guided Cochlear Implant Programming
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An Exploratory Clinical Study of SCAR02 Targeting BCMA and CD19 for the Treatment of Refractory Autoimmune Diseases
Status: RECRUITING
Conditions: Autoimmune Diseases
Interventions: DRUG: Anti-BCMA and CD19 CART cells will be injected intravenously on a one-time basis.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: S-Adenosyl-L-Methionine (SAMe) for Smoking Abstinence
Status: COMPLETED
Conditions: Tobacco Dependence
Interventions: DRUG: S-Adenosyl-L-Methionine|DRUG: S-Adenosyl-L-Methionine|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Roflumilast Plus Alogliptin Proof-of-Mechanism Study in Type2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: Roflumilast|DRUG: Alogliptin|DRUG: Exenatide|DRUG: Placebo to roflumilast|DRUG: Placebo to alogliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Efficacy of Escitalopram Monotherapy and Escitalopram in Adjuvant With Pizotifen in Depressive Disorder
Status: RECRUITING
Conditions: Depression
Interventions: DRUG: Pizotifen
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transversus Abdominis Plane Block Versus Quoadratus Lumborum Block on Infants
Status: UNKNOWN
Conditions: Transversus Abdominis Plane Block|Quoadratus Lumborum Block
Interventions: PROCEDURE: transversus abdominis plane block|PROCEDURE: quoadratus lumborum block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Opioid-limiting Pain Management Protocol in Men Undergoing Urethroplasty
Status: COMPLETED
Conditions: Pain, Postoperative|Urethral Stricture
Interventions: DRUG: Oxycodone|DRUG: Acetaminophen|DRUG: Gabapentin|DRUG: celebrex|DRUG: Bupivacaine|DRUG: Ibuprofen 800 mg|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hydroxychloroquine in Treating Patients With Newly Diagnosed Chronic Graft-Versus-Host Disease
Status: COMPLETED
Conditions: Graft Versus Host Disease
Interventions: DRUG: cyclosporine|DRUG: hydroxychloroquine|DRUG: prednisone|DRUG: tacrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of Ocrelizumab in Comparison With Interferon Beta-1a (Rebif) in Participants With Relapsing Multiple Sclerosis
Status: COMPLETED
Conditions: Relapsing Multiple Sclerosis
Interventions: DRUG: Interferon beta-1a|DRUG: Ocrelizumab-matching placebo|DRUG: Ocrelizumab|DRUG: Interferon beta-1a-matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A New Medicine to Treat Nonarteritic Anterior Ischemic Optic Neuropathy (NAION)
Status: COMPLETED
Conditions: Non Arteritic Ischemic Optic Neuropathy
Interventions: DRUG: dalfampridine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Trial Between a Computer-Guided Insulin Infusion Protocol Versus a Standard Insulin Infusion Algorithm in Medical ICU
Status: COMPLETED
Conditions: Diabetes or With New Hyperglycemia
Interventions: DEVICE: Glucommander|OTHER: Standard insulin infusion algorithm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing the New Anti-cancer Drug Eribulin With Chemotherapy Against the Usual Chemotherapy Alone in Metastatic Urothelial Cancer
Status: RECRUITING
Conditions: Metastatic Bladder Urothelial Carcinoma|Metastatic Renal Pelvis Urothelial Carcinoma|Metastatic Ureter Urothelial Carcinoma|Metastatic Urethral Urothelial Carcinoma|Metastatic Urothelial Carcinoma|Refractory Bladder Urothelial Carcinoma|Refractory Renal Pelvis Urothelial Carcinoma|Refractory Ureter Urothelial Carcinoma|Refractory Urethral Urothelial Carcinoma|Refractory Urothelial Carcinoma|Stage IV Bladder Cancer AJCC v8|Stage IV Renal Pelvis and Ureter Cancer AJCC v8|Stage IV Renal Pelvis Cancer AJCC v8|Stage IV Ureter Cancer AJCC v8|Stage IV Urethral Cancer AJCC v8|Stage IVA Bladder Cancer AJCC v8|Stage IVB Bladder Cancer AJCC v8
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Bone Scan|PROCEDURE: Computed Tomography|DRUG: Docetaxel|DRUG: Eribulin Mesylate|DRUG: Gemcitabine Hydrochloride|PROCEDURE: Magnetic Resonance Imaging|DRUG: Paclitaxel|BIOLOGICAL: Sacituzumab Govitecan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GLP-1 Agonism Stimulates Browning of Subcutaneous White Adipose Tissue in Obesity Men
Status: COMPLETED
Conditions: Obesity
Interventions: DRUG: Exenatide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized, Double-blind, Placebo-controlled Study on Immunogenicity and Safety of MVA-BN (IMVAMUNE™) Smallpox Vaccine in Healthy Subjects
Status: COMPLETED
Conditions: Smallpox
Interventions: BIOLOGICAL: MVA-BN® (IMVAMUNE)|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Characterization of Anti-HLA Alloimmunization After Pulmonary Valve Homograft Insertion
Status: NOT_YET_RECRUITING
Conditions: Lung Graft Dysfunction
Interventions: PROCEDURE: Blood collection T0|PROCEDURE: Blood collection 6 months
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Sequential Therapy (FK506 + Monoclonal Anti-IL2R Antibodies + MMF) Versus FK506 With Steroids in Liver TX
Status: COMPLETED
Conditions: Liver Transplantation
Interventions: DRUG: tacrolimus|DRUG: Anti-IL2R AB|DRUG: Mycophenolate mofetil|DRUG: prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pelvic Embolisation to Reduce Recurrent Varicose Veins - Recurrent
Status: UNKNOWN
Conditions: Varicose Veins|Venous Reflux|Pelvic Congestion Syndrome
Interventions: PROCEDURE: Coil embolisation|PROCEDURE: endovenous treatment of leg recurrent varicose veins
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Pharmacokinetics Of Sativex® in Subjects With Severe Renal Impairment or End Stage Renal Disease, Compared to Matched Subjects With Normal Renal Function.
Status: WITHDRAWN
Conditions: Renal Insufficiency|Kidney Disease
Interventions: DRUG: Sativex
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effectiveness of a Home Rehabilitation Program vs an e-Health Program in Patients With Chronic Low Back Pain
Status: COMPLETED
Conditions: Low Back Pain
Interventions: OTHER: Home Rehabilitation Program|OTHER: e-Health program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of a Single Nights' Wake Followed by Bright Light Therapy for Severe Depression
Status: TERMINATED
Conditions: Depression
Interventions: BEHAVIORAL: Single night's wake therapy|DEVICE: Bright light|OTHER: Treatment as usual - inpatient care|OTHER: Informative meeting|DRUG: Treatment as usual - medicine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cabazitaxel and BKM120 in Patients With Metastatic Castrate-Resistant Prostate Cancer (mCRPC) Previously Treated With Docetaxel
Status: WITHDRAWN
Conditions: Advanced Prostate Cancer
Interventions: DRUG: BKM 120|DRUG: Cabazitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Determining the Muscle Anabolic Properties of Phosphatidic Acid.
Status: COMPLETED
Conditions: Sarcopenia
Interventions: DIETARY_SUPPLEMENT: Phosphatidic Acid|DIETARY_SUPPLEMENT: Rice flour
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pilot Study Investigating Safety and Efficacy of Tadalafil as Treatment for Benign Prostatic Hyperplasia (BPH) in Asian Men
Status: COMPLETED
Conditions: Benign Prostatic Hyperplasia
Interventions: DRUG: Tadalafil|DRUG: Placebo|DRUG: Tamsulosin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An Exploratory Investigation of Dietary Supplementation and the Effect on Common PMS and Menstrual Symptoms
Status: COMPLETED
Conditions: Menstrual Pain|Menstrual Discomfort
Interventions: DIETARY_SUPPLEMENT: Semaine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of TPI 287 in Patients With Advanced Malignancies
Status: COMPLETED
Conditions: Neoplasms|Non-Hodgkin Lymphoma|Hodgkin Disease
Interventions: DRUG: TPI 287 Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Validation of the Percentage of Alveolar Fibrocyte as Biomarker During ARDS
Status: COMPLETED
Conditions: Acute Respiratory Distress Syndrome (ARDS)|Mechanical Ventilation
Interventions: OTHER: Bronchoalveolar lavage (BAL) before day 2 , between days 5-7 and days 10-14 of evolution.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Training of Inhalation Technique in Hospitalized Chronic Obstructive Pulmonary Disease (COPD) Patients - a Pilot Study
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: OTHER: Inhalation technique training and discharge service
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Effectiveness and Safety of Butylphthalide Soft Capsules in Secondary Prevention of Ischemic Stroke Trial
Status: UNKNOWN
Conditions: Stroke|Transient Ischemic Attack
Interventions: DRUG: Butylphthalide Soft Capsules|DRUG: Aspirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: MT2021-27 FT538 Recurrent Ovarian, Fallopian Tube, and Primary Peritoneal Cancer
Status: SUSPENDED
Conditions: Cancer|Solid Tumor|Ovarian Cancer|Peritoneal Cancer|Fallopian Tube Cancer
Interventions: DRUG: FT538|BIOLOGICAL: Enoblituzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dehydroepiandrosterone Administration in Women With Systemic Lupus Erythematosus or Primary Sjögren's Syndrome
Status: COMPLETED
Conditions: Lupus Erythematosus, Systemic|Sjogren's Syndrome
Interventions: DRUG: Dehydroepiandrosterone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Plerixafor Harvesting And No Chemotherapy for Transplantation of Autologous STem Cells In Cancer (PHANTASTIC)
Status: UNKNOWN
Conditions: Multiple Myeloma|Plasma Cell Dyscrasia|Lymphoma|Lymphoproliferative Disorders
Interventions: DRUG: Plerixafor and G-CSF
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Clorhexidine Dressings to Reduce Surgical Site Infections in Breast Cancer Surgery. A Controlled Clinical Trial
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DEVICE: Antiseptic occlusive dressing group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Nasal Intermittent Positive Pressure Ventilation In Newborn Infants With Respiratory Distress Syndrome
Status: COMPLETED
Conditions: Respiratory Distress Syndrome
Interventions: DEVICE: NIPPV|DEVICE: NIPPV|DEVICE: NIPPV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Gelesis200 on Appetite Parameters, Food Intake, and Glycemic Control in Overweight or Obese Prediabetic Subjects: A Sub-Study of LIGHT-UP
Status: COMPLETED
Conditions: Overweight and Obesity|PreDiabetes|Type2 Diabetes
Interventions: DEVICE: Gelesis200|DEVICE: Placebo|DEVICE: Gelesis200 and Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Multidisciplinary Weight Loss Program at AUB-MC
Status: UNKNOWN
Conditions: Obesity|Weight Loss
Interventions: OTHER: Multidisciplinary weight loss program|OTHER: Standard Care|DRUG: Metformin Hcl 850Mg Tab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Short-course Radiotherapy Combined With CapeOx and PD-1 Inhibitor After Local Excision for High-risk Early Rectal Cancer (TORCH-LE)
Status: RECRUITING
Conditions: Rectal Cancer
Interventions: RADIATION: Radiation|DRUG: PD-1 antibody|DRUG: Capecitabine|DRUG: Oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Simultaneous pHototherapeutic Keratectomy and corneAl Collagen cRosslinking in Eyes With Keratoconus: a Randomized Trial (SHARK)
Status: RECRUITING
Conditions: Keratoconus
Interventions: PROCEDURE: Corneal collagen cross linking (CXL)|PROCEDURE: Transepithelial phototherapeutic keratectomy (t-PTK)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of "Go On" in Magnetic Resonance Imaging (MRI) Improvement in Osteoarthritis (OA) Knee
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DRUG: 25 mg sodium hyaluronate "GO ON"|DRUG: normal saline,2 ml., intraarticular weekly for 5 weeks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Insulin Resistance, Polycystic Ovary Syndrome, and Bone Research Study
Status: COMPLETED
Conditions: Polycystic Ovary Syndrome
Interventions: DRUG: rosiglitazone|DRUG: drospirenone/ethinyl estradiol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Changing the Innate Consensus About Mesh Fixation in Trans-abdominal Preperitoneal Laparoscopic Inguinal Hernioplasty in Adults: Short and Long Term Outcome. Randomized Controlled Clinical Trial
Status: COMPLETED
Conditions: Hernia, Inguinal
Interventions: PROCEDURE: laparoscopic mesh fixation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Volume Controlled Ventilation and Autoflow-volume Controlled Ventilation in Robot-assisted Laparoscopic Radical Prostatectomy With Steep Trendelenburg Position and Pneumoperitoneum
Status: COMPLETED
Conditions: Robot-assisted Laparoscopic Radical Prostatectomy Undergoing General Anesthesia
Interventions: OTHER: Volume controlled ventilation|OTHER: Autoflow-volume controlled ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: An RCT of a Patient-initiated Treatment Service for BEB and HFS
Status: COMPLETED
Conditions: Blepharospasm|Hemi Facial Spasm
Interventions: OTHER: Patient-initiated treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Acute Effect of Static Stretching and Muscle Warming on the Functional Performance of College Volleyball Athletes
Status: COMPLETED
Conditions: Neuromuscular Manifestations
Interventions: OTHER: Static Stretching|OTHER: warm up|OTHER: static stretching + warm up|OTHER: warm up+static stretching|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Clinical Trial to Evaluate the Efficacy and Safety of Two Aramchol Doses Versus Placebo in Patients With NASH
Status: COMPLETED
Conditions: Fatty Liver|Non-Alcoholic Steatohepatitis|Liver Diseases|Liver Fibroses
Interventions: DRUG: Aramchol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Accuracy of Host-derived Biomarkers in Diagnosing Symptomatic and Asymptomatic Apical Periodontitis
Status: NOT_YET_RECRUITING
Conditions: Biomarkers
Interventions: DIAGNOSTIC_TEST: biomarkers
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Clinical Study Testing The Safety And Efficacy Of Crizotinib In East Asian Patients With Anaplastic Lymphoma Kinase (ALK) Positive Advanced Non-Small Cell Lung Cancer
Status: WITHDRAWN
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: Crizotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare Two Different Anti-HIV Drug Regimens
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Ritonavir|DRUG: Nelfinavir mesylate|DRUG: Nevirapine|DRUG: Stavudine|DRUG: Didanosine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: 68Ga-RM26-RGD PET/CT Imaging in the GRPR and αvβ3 Positive Tumor Patients
Status: RECRUITING
Conditions: Breast Cancer|Prostate Cancer|Brain Tumor|PET/CT Imaging
Interventions: DRUG: 68Ga-RM26-RGD|DRUG: 18F-FDG|DRUG: 68Ga-RM26|DRUG: 68Ga-RGD
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Trial of the Clinical and Cost Effectiveness of a Specialist Expert Mood Disorder Team for Refractory Unipolar Depressive Disorder
Status: UNKNOWN
Conditions: Chronic Unipolar Depressive Disorder
Interventions: OTHER: Specialist Mood Disorders Team
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Capecitabine and Oxaliplatin in Treating Patients With Locally Advanced, Unresectable, or Metastatic Stomach Cancer
Status: TERMINATED
Conditions: Gastric Cancer
Interventions: DRUG: capecitabine|DRUG: oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare Two Medications With an Inactive Medication and Look at the Effect on a Person's Mental Ability
Status: COMPLETED
Conditions: Cognition
Interventions: DRUG: Solifenacin|DRUG: Oxybutynin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Effectiveness of an APN-led Self-management Program in Patients in the First Year After Renal Transplantation
Status: COMPLETED
Conditions: Kidney Transplantation|Rental Transplantation
Interventions: BEHAVIORAL: Self-management program with monthly sessions|BEHAVIORAL: Usual Care, containing one session
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Repetitive Transcranial Magnetic Stimulation for Dementia
Status: ACTIVE_NOT_RECRUITING
Conditions: Dementia|Mild Cognitive Impairment
Interventions: DEVICE: RTMS|DEVICE: sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cognitive Behavioural Therapy for Youths With Depressive and Anxiety Symptoms in Hong Kong
Status: UNKNOWN
Conditions: Depressive Symptoms|Anxiety Symptoms
Interventions: BEHAVIORAL: Cognitive Behavioural Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Level of Continuous Positive Airway Pressure (CPAP) in Preterm Infants After Extubation (L-CPAP Study)
Status: TERMINATED
Conditions: Respiratory Insufficiency of Prematurity
Interventions: DEVICE: Nasal CPAP, level 7 to 9 cmH2O|DEVICE: Nasal CPAP, level 4 to 6 cmH2O
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Integrative Palliative Care/Psycho-Oncology Telehealth Intervention in Patients With Advanced Cancer
Status: COMPLETED
Conditions: Advanced Malignant Solid Neoplasm|Locally Advanced Malignant Solid Neoplasm|Metastatic Malignant Solid Neoplasm
Interventions: BEHAVIORAL: Support Group Therapy|BEHAVIORAL: Symptom Management Service (SMS) Consultation|OTHER: Quality of Life (QOL) Questionnaires|OTHER: Interview
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Clinical Study of Manpixiao in the Treatment of Chronic Atrophic Gastritis
Status: UNKNOWN
Conditions: Chronic Atrophic Gastritis
Interventions: DRUG: Manpixiao|DRUG: Active comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: QT Distance and P Dispersion in ECG in Patients Having Bronchoscopy in the ICU
Status: ENROLLING_BY_INVITATION
Conditions: Ventilator-Induced Lung Injury|Pulmonary Atelectasis
Interventions: DRUG: Midazolam|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: AR and ER Imaging in Metastatic Breast Cancer
Status: COMPLETED
Conditions: Metastatic Breast Cancer
Interventions: OTHER: FDHT-PET scan|OTHER: FES-PET scan|OTHER: CT-scan|OTHER: Bone scintigraphy|OTHER: Tumor biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of a Topical Patch (AB001) in Patients With Chronic Low Back Pain
Status: COMPLETED
Conditions: Chronic Low Back Pain
Interventions: DRUG: AB001 patch|OTHER: Placebo patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: IVIg Plus Low Dose rhTPO for ITP in Pregnancy
Status: NOT_YET_RECRUITING
Conditions: Immune Thrombocytopenia|Pregnancy Related
Interventions: DRUG: intravenous immunoglobulin plus low dose recombinant human thrombopoietin (rhTPO)|DRUG: intravenous immunoglobulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rapid Effects Linagliptin on Monocyte Polarization and Endothelial Progenitor Cells in Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes|Chronic Renal Failure
Interventions: DRUG: Linagliptin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate ELX/TEZ/IVA on Cough and Physical Activity in Participants With Cystic Fibrosis (CF)
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: ELX/TEZ/IVA|DRUG: IVA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial In Healthy HIV-Negative Women To Assess The Effect Of Menses And Tampon Use On The Pharmacokinetics Of Dapivirine, Delivered By Dapivirine Vaginal Ring-004, Containing 25 Mg Of Dapivirine
Status: COMPLETED
Conditions: HIV
Interventions: DRUG: Dapivirine Vaginal Ring-004 and no tampons|DRUG: Dapivirine Vaginal Ring-004 with tampons|DRUG: Dapivirine Vaginal Ring-004 with no menses|DRUG: Dapivirine Vaginal Ring-004 and same ring inserted after menses|DRUG: Dapivirine Vaginal Ring-004 and new ring inserted after menses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluating the Effect of the Automatic Surveillance System on Surveillance Rate of Colorectal Postpolypectomy Patients
Status: NOT_YET_RECRUITING
Conditions: Artificial Intelligence|Surveillance
Interventions: OTHER: AI based automatic surveillance (AS) system (ENDOANGEL-AS)|OTHER: Manually remind the patients to review.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SCREENING
Clinical trial: Fractional FLow Reserve And IVUS for Clinical OUtcomes in Patients With InteRmediate Stenosis
Status: UNKNOWN
Conditions: Stable Angina
Interventions: PROCEDURE: FFR-guided stenting|PROCEDURE: IVUS-guided stenting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BEFORE Study, Efficacy of Refigura
Status: COMPLETED
Conditions: Overweight and Obesity|Weight Loss|Efficacy, Self
Interventions: DRUG: Polyglucosamine Glucomannan normal dose (Verum)|DRUG: Polyglucosamine Glucomannan high dose (Verum)|DRUG: Placebo Comparator: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Choroidal Change on OCTA in Eyes With High Myopia
Status: NOT_YET_RECRUITING
Conditions: Myopia, Progressive|Choroid Disease
Interventions: DEVICE: Optic coherence tomography angiography (OCTA)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Drug Drug Interaction Study With Gabapentin Enacarbil and Morphine
Status: COMPLETED
Conditions: Restless Legs Syndrome
Interventions: DRUG: morphine Placebo|DRUG: GEn 600 mg|DRUG: Morphine|DRUG: GEn Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Gamma-linolenic Acid Supplementation Study
Status: COMPLETED
Conditions: Weight Trajectory
Interventions: DIETARY_SUPPLEMENT: gamma-linolenic acid|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Vitamin D to ENhance TraUma REcovery
Status: COMPLETED
Conditions: Musculoskeletal Pain
Interventions: DRUG: Vitamin D 2|DRUG: Vitamin D2 Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of a Melatonin Receptor Agonist to Prevent Migraine
Status: TERMINATED
Conditions: Migraine|Migraine With Aura|Migraine Without Aura
Interventions: DRUG: Ramelteon|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of the Combination of Ibuprofen and Paracetamol in Acute Non-specific Low Back Pain
Status: COMPLETED
Conditions: Low Back Pain
Interventions: DRUG: Tachifene|DRUG: Brufen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Single and Multiple Ascending Doses of PF-07059013 in Healthy Adult Participants
Status: TERMINATED
Conditions: Healthy
Interventions: DRUG: PF-07059013|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Cocamide DEA vs Permethrin for Head Lice
Status: TERMINATED
Conditions: Pediculosis Capitis|Head Louse Infestation
Interventions: DRUG: Cocamide diethanolamine|DRUG: Permethrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Isthmocele After Endometrial and Non-endometrial Suturing in Cesarean Section
Status: COMPLETED
Conditions: Cesarean Section; Dehiscence|Cesarean Wound; Dehiscence
Interventions: PROCEDURE: Closure of the uterus with endometrium at the time of cesarean|PROCEDURE: Closure of the uterus without endometrium at the time of cesarean
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Promoting Physical Activity in Older Hispanic/Latino(a) Adults
Status: NOT_YET_RECRUITING
Conditions: Sedentary Behavior|Physical Inactivity|Alzheimer Disease, Protection Against
Interventions: BEHAVIORAL: De Pie Intervention|OTHER: Active Comparison Group: Healthy Actions And Lifestyles To Avoid Dementia (HALT-AD)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: NY-ESO-1-Specific T-cells in Treating Patients With Advanced NY-ESO-1-Expressing Sarcomas Receiving Palliative Radiation Therapy
Status: COMPLETED
Conditions: Sarcoma
Interventions: BIOLOGICAL: Autologous NY-ESO-1-specific CD8-positive T Lymphocytes|OTHER: Laboratory Biomarker Analysis|RADIATION: Palliative Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chronic Headache and Chronic Backache Following Unintentional Dural Puncture at Delivery Room.
Status: COMPLETED
Conditions: Parturient Who Underwent Epidural Anesthesia During Which an Unintentional Dural Punctur Occurred|Parturient Who Develop a Postdural Puncture Headache|Parturient Who Gave Informed Consent to Participation in the Study
Interventions: OTHER: Epidural Blood patch.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy of Mechanical Ventilation With Facial Mask to Reduce Gastric Insufflation
Status: UNKNOWN
Conditions: Gastric Insufflation
Interventions: DEVICE: Mechanical ventilation with facial mask|DEVICE: Manual ventilation with facial mask
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of the Anti-inflammatory Effects of Norflo Oro in Acute Relapses of HLA-B27 Associated Autoimmune Uveitis
Status: COMPLETED
Conditions: Uveitis
Interventions: DRUG: Norflo Oro|DRUG: Placebo for Norflo Oro
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Validation of Questionnaire and Assessment of Patient Satisfaction for Budesonide/Formoterol Fix Combination Dry Powder Inhalers (DPI) in Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: An Open Label, Multi-Center, Randomized, Parallel Group Study Comparing the Efficacy and Safety of Insulin VIAject™ and Regular Human Insulin in Patients With Type 1 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus
Interventions: DRUG: VIAject™|DRUG: Regular Human Insulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Effect of Glutamine Supplementation on Chemotherapy Induced Toxicities in Breast Cancer Patients
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DIETARY_SUPPLEMENT: Glutamine|DIETARY_SUPPLEMENT: IV Glutamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Repurposed Approved and Under Development Therapies for Patients With Early-Onset COVID-19 and Mild Symptoms
Status: RECRUITING
Conditions: Covid19|SARS-Associated Coronavirus
Interventions: DIETARY_SUPPLEMENT: Spirulin Platensis|DRUG: Budesonide Powder|DRUG: Fluoxetine 20 MG|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Chronotherapy Randomized Controlled Trial
Status: TERMINATED
Conditions: Major Depressive Disorder|Bipolar Depression|Suicidal Ideation
Interventions: BEHAVIORAL: Total Sleep deprivation, Sleep Phase Advance, and Bright Light Therapy|BEHAVIORAL: Partial Sleep deprivation, Sleep Phase Delay, and Low amber light.|OTHER: Treatment as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: To Compare the Efficacy of Combined Tenofovir Plus Telbivudine vs Tenofovir Alone in Patients With Spontaneous Reactivation of Hepatitis B
Status: COMPLETED
Conditions: Spontaneous Reactivation of Hepatitis B
Interventions: DRUG: Tenofovir + Telbivudine|DRUG: Tenofovir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Auditory Deficits in Congenital Amusia (AMUSIE CONGENITALE)
Status: COMPLETED
Conditions: Healthy|Amusia, Congenital
Interventions: OTHER: Neuropsychological and neurophysiological tests|OTHER: Experiment 1|OTHER: Experiment 2|OTHER: Experiment 3|OTHER: Experiment 4
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of Encorafenib + Cetuximab Plus or Minus Binimetinib vs. Irinotecan/Cetuximab or Infusional 5-Fluorouracil (5-FU)/Folinic Acid (FA)/Irinotecan (FOLFIRI)/Cetuximab With a Safety Lead-in of Encorafenib + Binimetinib + Cetuximab in Patients With BRAF V600E-mutant Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: BRAF V600E-mutant Metastatic Colorectal Cancer
Interventions: DRUG: Encorafenib|DRUG: Binimetinib|DRUG: Cetuximab|DRUG: Irinotecan|DRUG: Folinic Acid|DRUG: 5-Fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Prophylactic Photobiomodulation Therapy in Patients With Osteosarcoma
Status: RECRUITING
Conditions: Mucositis Oral
Interventions: OTHER: Preventive photobiomodulation Therapy (PBMT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Early Vascular Healing in Acute Coronary Syndrome Patients With Different Doses of Rosuvastatin
Status: UNKNOWN
Conditions: Acute Coronary Syndrome
Interventions: DRUG: High dose Rosuvastatin|DRUG: Low dose Rosuvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Multicenter Randomized Controlled Study on the Treatment of Refractory CTIT With Romiplostim N01 Compared to Recombinant Human Thrombopoietin
Status: NOT_YET_RECRUITING
Conditions: CTIT-Chemotherapy Induced Thrombocytopenia
Interventions: DRUG: Romiplostim N01|DRUG: Recombinant Human Thrombopoietin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Lorundrostat in Addition to Sodium-Glucose Cotransporter-2 Inhibitors (SGLT2i) in Subjects With Hypertension and Chronic Kidney Disease (CKD) With Albuminuria
Status: RECRUITING
Conditions: Chronic Kidney Disease
Interventions: DRUG: Lorundrostat 25mg+SGLT2i QD, Washout, Placebo+SGLT2i QD|DRUG: Placebo QD + SGLT2i QD, Washout, Lorundrostat 25mg+SGLT2i QD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: The Natural History of Reproductive and Overall Health in Girls and Women With a Pre-Mutation in the FMR1 Gene; Creation of a Patient Registry
Status: TERMINATED
Conditions: Fragile X Syndrome|FMR1 Premutation|Primary Ovairan Insufficiency|Premature Ovarian Failure|Premature Menopause
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study to Evaluate the Clinical Performance of the Valiant Thoracic Stent Graft With the Captivia Delivery System (Valiant Captivia) for the Treatment of Acute, Complicated Type B Aortic Dissections
Status: COMPLETED
Conditions: Aortic Dissection
Interventions: DEVICE: Valiant Thoracic Stent Graft with the Captivia Delivery System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT