pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Early Immunotherapy With Intravenous Immunoglobulin, Cyclophosphamide and Methylprednisolone in Patients With Anti-Hu-associated Paraneoplastic Sensory Neuronopathy
Status: NOT_YET_RECRUITING
Conditions: Paraneoplastic Sensory Neuronopathy
Interventions: DRUG: Immunoglobulins IV (CLAYRIG)|DRUG: Cyclophosphamide IV|DRUG: Methylprednisolone IV
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: AK112 Plus AP Regimen for Operable Locally Advanced Head and Neck Squamous Cell Carcinoma
Status: NOT_YET_RECRUITING
Conditions: Neoadjuvant Therapy of Operable Locally Advanced Head and Neck Squamous Cell Carcinoma
Interventions: DRUG: AK112
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Exploration of Simulated Presence Therapy as a Formulation Based Intervention for Dementia Related Distress.
Status: UNKNOWN
Conditions: Behavioural and Psychiatric Symptoms of Dementia|Stress, Psychological
Interventions: BEHAVIORAL: Simulated Presence Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Anti-angiogenesis Agent AG-013736 in Patients With Metastatic Renal Cell Carcinoma
Status: COMPLETED
Conditions: Kidney Neoplasms
Interventions: DRUG: Vascular Endothelial Growth Factor Receptor [VEGFR] and Platelet-Derived Growth Factor Receptor [PDGFR] inhibitor
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Backside Massage and Lamaze Breathing on Labour Outcome Among Primigravida
Status: COMPLETED
Conditions: Labor Pain
Interventions: PROCEDURE: Routine Obstetrics care & Lamaze breathing techniques and backside massage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Trial for the Safety and Effectiveness of a Novel Antimicrobial-Coated Foley Catheter for Reduction of CAUTI.
Status: TERMINATED
Conditions: Urinary Tract Infection
Interventions: DEVICE: ICET™ TIC Foley Catheter|DEVICE: BARD® LUBRI-SIL® IC Foley Catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Parent-implemented Social Communication Treatment in Preschool Children With Autism Spectrum Disorder
Status: ACTIVE_NOT_RECRUITING
Conditions: Autism Spectrum Disorder|Autism|Social Communication|Speech Therapy|Parenting
Interventions: BEHAVIORAL: Group-based Parent-implemented Training|BEHAVIORAL: Individual-based Parent-implemented Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Manual Lymphatic Drainage Following Total Knee Arthroplasty Surgery
Status: COMPLETED
Conditions: Knee Arthroplasty, Total
Interventions: OTHER: Manual lymphatic drainage|OTHER: relaxation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: LAMELLEYE for the Treatment of Dry Eye Symptoms in pSS Patients
Status: UNKNOWN
Conditions: Dry Eye Syndromes|Primary Sjögren Syndrome
Interventions: DEVICE: LAMELLEYE|DEVICE: OPTIVE FUSION
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: First-line Treatment of Patients With Stage IV Nonsquamous Non-Small Cell Lung Cancer With Necitumumab (IMC-11F8) and Pemetrexed-Cisplatin
Status: COMPLETED
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: Pemetrexed|DRUG: Cisplatin|BIOLOGICAL: Necitumumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Selpercatinib Before Surgery for the Treatment of RET-Altered Thyroid Cancer
Status: RECRUITING
Conditions: Malignant Thyroid Gland Neoplasm|Poorly Differentiated Thyroid Gland Carcinoma|Recurrent Thyroid Gland Carcinoma|Thyroid Gland Anaplastic Carcinoma|Thyroid Gland Medullary Carcinoma|Thyroid Gland Papillary Carcinoma|Thyroid Gland Squamous Cell Carcinoma
Interventions: OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration|DRUG: Selpercatinib|PROCEDURE: Therapeutic Conventional Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Erlotinib in Combination With Pralatrexate in Advanced Malignancies
Status: COMPLETED
Conditions: Advanced Cancers|Solid Tumors
Interventions: DRUG: Erlotinib|DRUG: Pralatrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chinese Medicine Treat for Hypertensive Renal Injury
Status: UNKNOWN
Conditions: Hypertension|Renal Injury
Interventions: DRUG: Losartan 100Mg Tab|DRUG: Qianyangyuyin 20g Granule|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of S-033188 (Baloxavir Marboxil) Compared With Placebo or Oseltamivir in Patients With Influenza at High Risk of Influenza Complications
Status: COMPLETED
Conditions: Influenza
Interventions: DRUG: Baloxavir Marboxil|DRUG: Placebo to Baloxavir Marboxil|DRUG: Oseltamivir|DRUG: Placebo to Oseltamivir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Premedication on Success of Inferior Alveolar Nerve Block Injection
Status: COMPLETED
Conditions: Irreversible Pulpitis
Interventions: DRUG: Ketorolac Tromethamine|DRUG: Acetaminophen|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vitamin D Deficiency in Elderly African American Women in Central Texas
Status: COMPLETED
Conditions: Vitamin D Deficiency|Osteoporosis|Osteopenia
Interventions: DRUG: Calcium 500mg with 200 IU Vitamin D - 2 tablets daily|PROCEDURE: Blood levels of Vitamin D, Serum CTX, Mg, Ca++ and iPTH|BEHAVIORAL: Usual sun exposure documentation|BEHAVIORAL: Dietary intake of calcium, vitamin D, magnesium
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Translating Metabolic Responses to Mechanical Insult Into Early Interventions to Prevent PTOA
Status: COMPLETED
Conditions: Osteoarthritis|Post-traumatic Osteoarthritis
Interventions: DRUG: amobarbital/Gel-One (one dose)|DRUG: Placebo (single dose)|DRUG: amobarbital/Gel-One (two doses)|DRUG: Placebo (two doses)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rituximab, Rasburicase, and Combination Chemotherapy in Treating Young Patients With Newly Diagnosed Advanced B-Cell Leukemia or Lymphoma
Status: COMPLETED
Conditions: Childhood Burkitt Lymphoma|Childhood Diffuse Large Cell Lymphoma|Childhood Immunoblastic Large Cell Lymphoma|Stage I Childhood Large Cell Lymphoma|Stage I Childhood Small Noncleaved Cell Lymphoma|Stage II Childhood Large Cell Lymphoma|Stage II Childhood Small Noncleaved Cell Lymphoma|Stage III Childhood Large Cell Lymphoma|Stage III Childhood Small Noncleaved Cell Lymphoma|Stage IV Childhood Large Cell Lymphoma|Stage IV Childhood Small Noncleaved Cell Lymphoma|Untreated Childhood Acute Lymphoblastic Leukemia
Interventions: DRUG: doxorubicin hydrochloride|DRUG: cyclophosphamide|DRUG: methotrexate|DRUG: rasburicase|DRUG: leucovorin calcium|DRUG: prednisone|DRUG: methylprednisolone|BIOLOGICAL: filgrastim|BIOLOGICAL: rituximab|DRUG: cytarabine|DRUG: etoposide|DRUG: vincristine sulfate|DRUG: hydrocortisone sodium succinate|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral Pooled Fecal Microbiotherapy to Prevent Allogeneic Hematopoietic Cell Transplantation Complications (PHOEBUS Trial)
Status: RECRUITING
Conditions: Transplant Complication
Interventions: DRUG: Pooled allogeneic fecal microbiotherapy|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Combination Chemotherapy in Treating Patients With Metastatic Solid Tumors
Status: COMPLETED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: irinotecan hydrochloride|DRUG: pemetrexed disodium
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: A Study of INO-3112 DNA Vaccine With Electroporation in Participants With Cervical Cancer
Status: COMPLETED
Conditions: Cervical Cancer
Interventions: BIOLOGICAL: INO-3112|DEVICE: CELLECTRA™-5P
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety and Efficacy of Filgotinib and Lanraplenib in Adults With Lupus Membranous Nephropathy (LMN)
Status: COMPLETED
Conditions: Lupus Membranous Nephropathy
Interventions: DRUG: Filgotinib|DRUG: Lanraplenib|DRUG: Filgotinib placebo|DRUG: Lanraplenib placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Anti-malaria MAb in Malian Children
Status: COMPLETED
Conditions: Plasmodium Falciparum Infection|Malaria
Interventions: BIOLOGICAL: L9LS (VRC-MALMAB0114-00-AB) Subcutaneous injection|BIOLOGICAL: L9LS (VRC-MALMAB0114-00-AB) intravenous injection|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Dental Isolation Systems Among Pediatric Patients With Different Airway Patency
Status: NOT_YET_RECRUITING
Conditions: Airway Obstruction|Pain|Behavior
Interventions: DEVICE: Rubber Dam Isolation|DEVICE: DryShieled isolation|OTHER: fissure sealant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Subcostal Transversus Abdominis Block Versus Erector Spinae Block in Open Cholecystectomy
Status: NOT_YET_RECRUITING
Conditions: Post Operative Pain, Acute
Interventions: PROCEDURE: Subcostal Transversus Abdominis Plane block in patients undergoing open cholecystectomy surgery.|PROCEDURE: Erector Spinae Block in patients undergoing open cholecystectomy|DRUG: Sbcostal transversus Abdominis block and erector spinae block for both groups
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phase I/II Study of Hydroxychloroquine With Itraconazole With Biochemically Recurrent Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: SUBA-itraconazole|DRUG: Hydroxychloroquine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CHRONVAC-C Study Followed by Standard of Care in Chronic Hepatitis C Virus (HCV) Subjects
Status: UNKNOWN
Conditions: Chronic Hepatitis C
Interventions: DRUG: ChronVac-C + SOC|DRUG: SOC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Analysis of Next Generation PET and Liquid Biopsy to Monitor mCRPC Treated With Abiraterone: ANGELA Trial
Status: UNKNOWN
Conditions: Prostate Cancer|Castration-resistant Prostate Cancer|Metastatic Disease
Interventions: DRUG: Abiraterone|DRUG: Prednisone|DRUG: Androgen deprivation therapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of the Effect of the ROX AC1 on Exercise Capacity and Quality of Life in Chronic Obstructive Pulmonary Disease (COPD) Patients
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DEVICE: Arteriovenous Fistula (ROX AC1)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clarithromycin 500 mg Extended Release Tablets Under Fasting Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Clarithromycin ER 500 mg tablets|DRUG: BIAXIN® XL 500 mg tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Comparison of Oxidative Stress and Insulin Resistance Before and After Using Physioneal in Peritoneal Dialysis Patients
Status: COMPLETED
Conditions: Kidney Failure,Chronic
Interventions: DRUG: Physioneal
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimizing Access to Care Through New Technologies: a Randomized Study Evaluating the Impact of Telephone Contact and the Sending by the General Practitioner of Suspicious Lesions Melanoma Photographs Taken With a Smartphone, on the Time Limit to the Consultation With a Dermatologist
Status: COMPLETED
Conditions: Patients at Risk for Melanoma
Interventions: OTHER: Taking photographs of suspicious lesions with his smartphone and sending them to the dermatologist
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Brain Stimulation for Patients With Parkinson Disease
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: DEVICE: TPS (NEUROLITH)|DEVICE: Sham-TPS (NEUROLITH)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tension Type Headache, Myofascial Release Therapy , Post Isometric Relaxation Technique
Status: COMPLETED
Conditions: Neck Pain
Interventions: OTHER: Myofascial release therapy therapy|OTHER: Post isometric relaxation technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of SDX-101 (R-Etodolac) in Patients With Relapsed or Refractory Multiple Myeloma (MM)
Status: TERMINATED
Conditions: Multiple Myeloma
Interventions: DRUG: SDX-101 (R-Etodolac)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cell Therapy for High Risk T-Cell Malignancies Using CD7-Specific CAR Expressed On Autologous T Cells
Status: RECRUITING
Conditions: T-cell Acute Lymphoblastic Lymphoma|T-non-Hodgkin Lymphoma|T-cell Acute Lymphoblastic Leukemia
Interventions: GENETIC: CD7.CAR/28zeta CAR T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fascia Iliaca Compartment Block Versus Anterior Quadratus Lumborum Block
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: PROCEDURE: Facia Iliaca block|PROCEDURE: Anterior Quadratus Lumbroum block|DRUG: bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Continuing Care Following Drug Abuse Treatment: Linkage With Primary Care
Status: ACTIVE_NOT_RECRUITING
Conditions: Substance Abuse|Substance Dependence|Substance, Addiction|Alcohol Abuse
Interventions: BEHAVIORAL: Linkage patient activation intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Comparison of Intravenous Injection of Calcium Antagonist and Beta-blockade on Endothelial Shear Stress of Coronary Artery
Status: UNKNOWN
Conditions: Acute Coronary Syndrome|Coronary Artery Disease
Interventions: DRUG: Nicardipine , Esmolol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Working Memory Training in Young ADHD Children
Status: COMPLETED
Conditions: Attention Deficit Disorder With Hyperactivity
Interventions: BEHAVIORAL: Cogmed Working memory training|BEHAVIORAL: Control version of Cogmed working memory training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Effectiveness of MRgFUS Versus CTgRFA for Osteoid Osteomas
Status: RECRUITING
Conditions: Osteoid Osteoma
Interventions: DEVICE: MRgFUS|DEVICE: CTgRFA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy Plus Amifostine in Treating Children With Malignant Germ Cell Tumors
Status: COMPLETED
Conditions: Childhood Germ Cell Tumor|Drug/Agent Toxicity by Tissue/Organ|Extragonadal Germ Cell Tumor|Ovarian Cancer
Interventions: BIOLOGICAL: bleomycin sulfate|DRUG: amifostine trihydrate|DRUG: cisplatin|DRUG: etoposide|PROCEDURE: conventional surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Fursultiamine in Esophageal Squamous Cell Carcinoma Patients Who Receive Concurrent Chemoradiotherapy
Status: COMPLETED
Conditions: Cancer Stem Cell
Interventions: DIETARY_SUPPLEMENT: Fursultiamine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Telephone Intervention to Improve Participation in a Screening Program.
Status: COMPLETED
Conditions: Colorectal Cancer|Colorectal Neoplasms
Interventions: OTHER: Phone call|OTHER: Invitation letter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Functional Yogurt Consumption and Its Effects on the Lipid Profile of Healthy Subjects
Status: COMPLETED
Conditions: Cardiovascular Diseases|Apolipoproteins|Food Preferences|Low-density-lipoprotein-type|HDL|Triglycerides|Functional Food
Interventions: OTHER: Sacha inchi oil yogurt|OTHER: Hybrid palm oil yogurt|OTHER: Control yogurt
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: First rTMS for Treatment of Drug Induced Tardive Syndromes. Double Randomized Clinical Trial
Status: COMPLETED
Conditions: Drug Induced Tardive Syndrome (DITS)
Interventions: PROCEDURE: Repetitive transcranial magnetic stimulation (rTMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Percutaneous Revascularization in Infarction With Late Presentation and Absence of Viability: Effects on Left Ventricular Remodeling and Contractility
Status: UNKNOWN
Conditions: STEMI - ST Elevation Myocardial Infarction|Myocardial Dysfunction|Percutaneous Coronary Intervention
Interventions: DRUG: Optimized Medical Treatment (OMT)|DEVICE: Drug Eluting Stent (DES) Coronary Angioplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neuromodulation for Schizophrenia
Status: NOT_YET_RECRUITING
Conditions: Schizophrenia
Interventions: DEVICE: Non-invasive brainstem modulation device (stimulation Randomized)|DEVICE: Non-invasive brainstem modulation device (stimulation-Open Label)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Skin Safety Profile of Different Exposure to the Light Emitting Diode (LED) in Healthy Subjects
Status: COMPLETED
Conditions: Radiation Tolerance|Skin Aging|Rhytids
Interventions: DEVICE: LED GentleWaves®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Cervical Capsaicin for Labor Induction and Pain Relief
Status: WITHDRAWN
Conditions: Labor Pain|Pregnancy Loss|Labor Induction
Interventions: DRUG: capsaicin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Constipation Bundle/Protocol and the Effect of Adherence in the Incidence of Constipation in Critically Ill Patients
Status: COMPLETED
Conditions: Constipation|Critical Illness|Constipation Drug Induced
Interventions: PROCEDURE: Implementation of management pharmacological protocol of constipation|PROCEDURE: Implementation of bundle of prevention and non-pharmacological management
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pegfilgrastim vs. Filgrastim - Comparison of Mobilized Blood Stem Cells in Patients With Non Hodgkin-lymphoma
Status: COMPLETED
Conditions: Non-Hodgkin Lymphoma
Interventions: DRUG: pegfilgrastim
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Stem Cell Therapy in Patients With Autism
Status: COMPLETED
Conditions: Autism
Interventions: BIOLOGICAL: human cord blood mononuclear cells|BIOLOGICAL: human cord blood mononuclear cells and human umbilical cord mesenchymal stem cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Prediction Study of Multiple Indexes of the Effect of Different Mechanisms of Antidepressants Treatment on Depression
Status: UNKNOWN
Conditions: Major Depressive Disorder|Depression, Unipolar
Interventions: DRUG: Escitalopram|DRUG: Duloxetine|DRUG: Bupropion|OTHER: Healthy control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevention of Venous Thromboembolism in Subjects Undergoing Hip Fracture Surgery or Surgery in the Lower Extremities
Status: COMPLETED
Conditions: Venous Thromboembolism
Interventions: DRUG: YM150
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Observation of the Effect of Chemotherapy Combined With Tyrosinase Inhibitor on the Reactivation of CMV and EBV in Patients With Acute Lymphoblastic Leukemia
Status: UNKNOWN
Conditions: Leukemia, Lymphoblastic, Acute
Interventions: DRUG: TKIs
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Enhancing Weight Loss Maintenance With GLP-1RA (BYDUREON™) in Adolescents With Severe Obesity
Status: COMPLETED
Conditions: Severe Obesity
Interventions: DRUG: Weight loss with pharmacotherapy|DRUG: Weight loss without pharmacotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Omalizumab as Add on Therapy for Minority Patients With Moderate to Severe Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Omalizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Vitamin D Supplementation and Muscle Function in Older Adults
Status: COMPLETED
Conditions: Neuromuscular Function
Interventions: DIETARY_SUPPLEMENT: Vitamin D|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Natural History Study of Cutaneous Neurofibromas in People With NF1
Status: RECRUITING
Conditions: Neurofibromatosis Type 1|Neurofibromatosis 1|Neurofibromatosis (Nonmalignant)|Cutaneous Neurofibroma
Interventions: OTHER: Evaluation of the natural history of cutaneous neurofibromas
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Cryaoablation Assisted Partial Nephrectomy a Non Ischemic Approach
Status: RECRUITING
Conditions: Kidney Neoplasms
Interventions: DEVICE: Cryoablation Assisted Partial Nephrectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pharmacokinetic Study of Avanfil in Healthy Young Male Subjects
Status: COMPLETED
Conditions: Avanfil ADME|Semen Exposure|Sperm Function
Interventions: DRUG: avanafil 200mg|DRUG: avanafil 200mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Long Term Effects of DPP-IV Inhibitor Treatment in Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: Januvia|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: IFNα Expressing Mesenchymal Stromal Cells for Locally Advanced/Metastatic Solid Tumors
Status: RECRUITING
Conditions: Locally Advanced or Metastatic Solid Tumors
Interventions: BIOLOGICAL: MSC-IFNα|DRUG: Nab paclitaxel|DRUG: Cyclophosphamide|DRUG: Anti-PD-1 monoclonal antibody
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of AK002 in Patients With Atopic Keratoconjunctivitis, Vernal Keratoconjunctivitis, and Perennial Allergic Conjunctivitis
Status: COMPLETED
Conditions: Atopic Keratoconjunctivitis|Vernal Keratoconjunctivitis|Perennial Allergic Conjunctivitis
Interventions: DRUG: AK002
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Effect of Curcumin Supplementation on Recovery From Exercise-induced Muscle Damage
Status: UNKNOWN
Conditions: Exercise Induced Muscle Damage
Interventions: DIETARY_SUPPLEMENT: Curcumin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Treatment of Hepatorenal Syndrome With Terlipressin Infusion Adjusted to Hemodynamic Response
Status: UNKNOWN
Conditions: Cirrhosis|Hepatorenal Syndrome Type I
Interventions: DRUG: Terlipressin and albumin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Extubation Techniques in Critically Ill Adult Patients
Status: TERMINATED
Conditions: Weaning Failure|Mechanical Ventilation Complication
Interventions: PROCEDURE: Positive Pressure Extubation Technique|PROCEDURE: Traditional Extubation Technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: GLucose Monitoring Programme SingaporE, Phase 2 (GLiMPSE2)
Status: ACTIVE_NOT_RECRUITING
Conditions: Diabetes Mellitus, Type 2|Flash Glucose Monitoring
Interventions: COMBINATION_PRODUCT: Flash Glucose Monitoring and Education|COMBINATION_PRODUCT: Capillary glucose monitoring and Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Buparid/PARI SINUS Versus Budes® Nasal Spray in the Therapy of Chronic Rhinosinusitis With Polyposis Nasi
Status: COMPLETED
Conditions: Rhinosinusitis|Chronic Polyposis
Interventions: DRUG: Budesonide|DRUG: Budesonide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics (PK) and Safety of Subgam-VF in Primary Immunodeficiency Diseases
Status: COMPLETED
Conditions: Primary Immune Deficiency Disorders|Common Variable Immunodeficiency|X-linked Agammaglobulinaemia|Hyperimmunoglobulin M Syndrome
Interventions: BIOLOGICAL: Subgam
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effects of Exercise Intervention and Confounding Factors on Type II Diabetic Muscles
Status: COMPLETED
Conditions: Diabetes and Healthy Control|FTO Gene Expression|Aerobic Exercise Intervention or Home Exercise|Pre-training and Post-training
Interventions: BEHAVIORAL: supervised aerobic exercise or home-based aerobic exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Inhaled GM-CSF Therapy of Autoimmune PAP
Status: COMPLETED
Conditions: Autoimmune Pulmonary Alveolar Proteinosis
Interventions: PROCEDURE: Baseline WLL|DRUG: Sargramostim|PROCEDURE: Rescue WLL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparison of the Post-C/S Analgesic Effects of Neuraxial Duramorph vs Bilateral TAP Block With Liposomal Bupivacaine
Status: TERMINATED
Conditions: Caesarean Section
Interventions: DRUG: Exparel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Acupuncture Stimulation on Systemic Inflammation
Status: UNKNOWN
Conditions: Nonsmall Cell Lung Cancer
Interventions: PROCEDURE: Acupuncture stimulation|PROCEDURE: Sham stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Preliminary Efficacy of Different Exercise Training During Immunotherapy in Patients With Lung Cancer: The ENHANCE Trial
Status: RECRUITING
Conditions: Lung Cancer
Interventions: BEHAVIORAL: High-Intensity Interval Training (HIIT)|BEHAVIORAL: Moderate-Intensity Continuous Training (MICT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of HD Mesh Ablation System for Treatment of Paroxysmal Atrial Fibrillation
Status: TERMINATED
Conditions: Paroxysmal Atrial Fibrillation
Interventions: DEVICE: HD Mesh Ablation System|DRUG: Anti-arrhythmic drugs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: FMT+Immunotherapy+Chemotherapy as First-line Treatment for Driver-gene Negative Advanced NSCLC
Status: NOT_YET_RECRUITING
Conditions: Non-small Cell Lung Cancer
Interventions: COMBINATION_PRODUCT: Fecal Microbiota Transplantation (FMT)+chemotherapy+immunotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Perioperative Lidocaine Infusion on Neutrophil Extracellular Trapping
Status: ACTIVE_NOT_RECRUITING
Conditions: Urologic Cancer
Interventions: DRUG: lidocaine group|DRUG: control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Feasibility Study of Chemoradiation, TRAstuzumab and Pertuzumab in Resectable HER2+ Esophageal Carcinoma
Status: COMPLETED
Conditions: Esophageal Carcinoma
Interventions: DRUG: Pertuzumab, trastuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preoperative Levator Ani Muscle Injection and Pudendal Nerve Block for Pain Control After Vaginal Reconstructive Surgery
Status: COMPLETED
Conditions: Pelvic Organ Prolapse|Surgery|Postoperative Pain
Interventions: DRUG: Dexamethasone|DRUG: Bupivacaine|PROCEDURE: Bilateral Pudendal Nerve Block|PROCEDURE: Bilateral Levator Ani Muscle Injection|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hetrombopag for the Treatment of Chemotherapy-Induced Thrombocytopenia(CIT) in Patients With Acute Myeloid Leukemia
Status: NOT_YET_RECRUITING
Conditions: Chemotherapy-Induced Thrombocytopenia
Interventions: DRUG: Hetrombopag Olamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TXA127 in Enhancement of Engraftment in Adult Double Cord Blood Transplantation
Status: TERMINATED
Conditions: Double Cord Blood Transplant|Acute Myelogenous Leukemia|Myelodysplastic Syndrome|Myelofibrosis|Acute Lymphoblastic Leukemia|Chronic Myelocytic Leukemia|Non Hodgkins Lymphoma|Hodgkins Lymphoma|Chronic Lymphocytic Leukemia
Interventions: DRUG: TXA127 300 mcg/kg/day|DRUG: TXA127 1000 mcg/kg/day
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Improving Glucose and Lipid Metabolism Through Caloric Restriction Using Diet or Surgery (CRUDOS)
Status: UNKNOWN
Conditions: Type2 Diabetes|Weight Loss|Insulin Sensitivity|Metabolism and Nutrition Disorder|Metabolism Disorder, Glucose|Bariatric Surgery Candidate
Interventions: PROCEDURE: Gastric by-pass surgery|DIETARY_SUPPLEMENT: Low-caloric diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Racecadotril Suspension Linearity Study & Comparative Bioavailability Versus Granules
Status: COMPLETED
Conditions: Healthy Male Volunteers
Interventions: DRUG: Racecadotril suspension|DRUG: Racecadotril granules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Manual Therapy, Thera-band Exercise and Walking
Status: COMPLETED
Conditions: Aging
Interventions: OTHER: Group1, walking group|OTHER: Group 2, Walking plus manual therapy|OTHER: Group 3; Walking plus exercises with Theraband
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Laser Induced Bioengineered Remodeling of Thermally Injured Skin Trial
Status: WITHDRAWN
Conditions: Hypertrophic Scars
Interventions: PROCEDURE: CO2 laser treatment|PROCEDURE: PDL laser treatment|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Home-Based Peer Support on Maternal-Infant Interaction and Postpartum Depression
Status: COMPLETED
Conditions: Postpartum Depression
Interventions: BEHAVIORAL: mci guidance peer support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Efficacy & Safety Evaluation of Enobosarm in Combo With Abemaciclib in Treatment of ER+HER2- Metastatic Breast Cancer
Status: TERMINATED
Conditions: Metastatic Breast Cancer
Interventions: DRUG: Enobosarm & Abemaciclib Combo|DRUG: non-steroidal AI, or steroidal AI (exemestane with or without everolimus) or Fulvestrant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Switching or Adding Pegylated Interferon in Chronic Hepatitis B Patients on Long Term Oral Antiviral Therapy
Status: COMPLETED
Conditions: Chronic Hepatitis B
Interventions: DRUG: peg-interferon alpha 2b, 1.5mcg/kg s/c given weekly|DRUG: Nucleos(t)ide analogue therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Impact of Palm Date Intake on Colon Health Biomarkers
Status: COMPLETED
Conditions: Colon Cancer
Interventions: DIETARY_SUPPLEMENT: Date fruit - Ajwa variety|DIETARY_SUPPLEMENT: Maltodextrin/Dextrose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Observational Registry of NovoSeven® Used as On-demand Treatment of Bleeds in Patients With Haemophilia A and B With Inhibitors
Status: COMPLETED
Conditions: Congenital Bleeding Disorder|Haemophilia A With Inhibitors|Haemophilia B With Inhibitors
Interventions: DRUG: eptacog alfa (activated)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: An International Phase 2 Study Of SU011248 In Patients With Advanced / Metastatic Gastric Cancer Failing Chemotherapy
Status: COMPLETED
Conditions: Stomach Neoplasms
Interventions: DRUG: Sunitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial Comparing Decompression With and Without Coflex™ Interlaminar Technology Treating Lumbar Spinal Stenosis
Status: COMPLETED
Conditions: Spinal Stenosis
Interventions: DEVICE: Implantation of coflex™ after surgical decompression|PROCEDURE: Surgical decompression
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Genetic and Epigenetic Determinants of Response to Fluorouracil-based Adjuvant Chemotherapy in Patients With Stage III Colorectal Cancer
Status: NOT_YET_RECRUITING
Conditions: Stage III Colorectal Cancer
Interventions: GENETIC: Gene mutations analysis|GENETIC: Gene methylation analysis|GENETIC: Gene expression analysis|GENETIC: SNP analysis|GENETIC: Protein expression analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Metformin Combined With Chemotherapy for Pancreatic Cancer
Status: COMPLETED
Conditions: Locally Advanced Pancreatic Cancer|Metastatic Pancreatic Cancer
Interventions: DRUG: gemcitabine|DRUG: erlotinib|DRUG: metformin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: C1 Esterase Inhibitor (C1INH-nf) for the Treatment of Acute Hereditary Angioedema (HAE) Attacks
Status: COMPLETED
Conditions: Hereditary Angioedema
Interventions: BIOLOGICAL: C1 esterase inhibitor [human] (C1INH-nf)|DRUG: Placebo (saline)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Benefit and Tolerability of IQP-LU-104 in Weight Loss
Status: COMPLETED
Conditions: Overweight|Obesity
Interventions: DIETARY_SUPPLEMENT: High dose IQP-LU-104 (5120mg)|DIETARY_SUPPLEMENT: Low dose IQP-LU-104 (2560mg)|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 1b of Lurbinectedin in Combination With Weekly Paclitaxel and Bevacizumab in Platinum-resistant Ovarian Cancer
Status: RECRUITING
Conditions: Ovarian Cancer
Interventions: DRUG: Paclitaxel|DRUG: Bevacizumab|DRUG: Lurbinectedin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Telemonitoring System for Improving Continuity of Care in Patients With Chronic Coronary Syndrome (TELSINCORC)
Status: RECRUITING
Conditions: Chronic Coronary Syndrome
Interventions: DEVICE: telemonitoring|OTHER: control follow-up
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Incisional Negative Pressure Dressing on Clean Closed Groin Incisions
Status: WITHDRAWN
Conditions: Complication of Surgical Procedure
Interventions: DEVICE: Incisional Neg Pressure Wound Therapy (Prevena™)|OTHER: Standard of Care wound therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of Susu Zhike Granules for Treating Acute Cough Due to Common Cold With Cold-cough Syndrome in Children
Status: COMPLETED
Conditions: Cough
Interventions: DRUG: High dose Susu Xiao'er Zhike Granules 1 bag|DRUG: Middle dose Susu Xiao'er Zhike Granules 1 bag|DRUG: Extremely-low dose Susu Xiao'er Zhike Granules 1 bag
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Robotic Assisted Upper-Limb Neurorehabilitation in Stroke Patients
Status: COMPLETED
Conditions: Stroke
Interventions: DEVICE: Robot-Assisted Therapy - MIT-MANUS System|OTHER: Intensive Comparison Therapy|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective Study of an Investigational Toric Soft Contact Lens
Status: COMPLETED
Conditions: Myopia|Astigmatism|Refractive Error
Interventions: DEVICE: Nelfilcon A toric contact lenses (with comfort additives)|DEVICE: Nelfilcon A toric contact lenses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Analgesic Efficacy of Intravenous Lidocaine for Postoperative Pain Following Adult Spine Surgery
Status: WITHDRAWN
Conditions: Back Pain
Interventions: DRUG: Lidocaine Hydrochoride Injection, without epinephrine|DRUG: Normal Saline|DRUG: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Pyrotinib Versus Pertuzumab in Combination With Neoadjuvant Trastuzumab and Nab-Paclitaxel in HER2+ Early or Locally Advanced Breast Cancer
Status: NOT_YET_RECRUITING
Conditions: HER2+ Early or Locally Advanced Breast Cancer
Interventions: DRUG: pyrotinib + trastuzumab + nab-paclitaxel|DRUG: pertuzumab + trastuzumab + nab-paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Effect of Diltiazem Extended Release on the Pharmacokinetics of E2027 in Healthy Subjects
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: E2027|DRUG: Diltiazem ER
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess Safety & Effectiveness of Tovinontrine in Chronic Heart Failure With Reduced Ejection Fraction (Cycle-1-REF)
Status: RECRUITING
Conditions: Heart Failure|Heart Failure With Reduced Ejection Fraction|Cardiovascular Diseases|Heart Diseases
Interventions: DRUG: Tovinontrine (CRD-750)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Total Knee Arthroplasty Utilizing Adductor Canal Block: Effect on Quadriceps Sparing
Status: TERMINATED
Conditions: Osteoarthritis (Knee)
Interventions: PROCEDURE: High Volume Adductor Canal Block|PROCEDURE: Low Volume Adductor Canal Block|PROCEDURE: Femoral Nerve Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Weight-bearing of Surgically Treated Acetabular Fractures.
Status: NOT_YET_RECRUITING
Conditions: Acetabular Fracture
Interventions: PROCEDURE: Open reduction and internal fixation (ORIF)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating an Amino Acid Based Medical Food w/ Diarrhea in Carcinoid Syndrome & Other NETs
Status: COMPLETED
Conditions: Neuroendocrine Tumors|Carcinoid Tumor of GI System|Diarrhea|Carcinoid Syndrome
Interventions: DIETARY_SUPPLEMENT: Amino Acid Based Medical Food/Drink
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of Ametumumab in Combination With Anti-PD-1 Monoclonal Antibody and FOLFIRI in Patients With RAS Wild-type Advanced Colorectal Cancer
Status: NOT_YET_RECRUITING
Conditions: Colorectal Cancer
Interventions: DRUG: Ametumumab|DRUG: Anti-PD-1 monoclonal antibody|DRUG: Cetuximab|DRUG: FOLFIRI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Noninvasive Markers of Functional Nausea in Children
Status: ENROLLING_BY_INVITATION
Conditions: Nausea
Interventions: DIAGNOSTIC_TEST: Questionnaires|DIAGNOSTIC_TEST: 4 channel electrogastrogram (EGG)|DIAGNOSTIC_TEST: 36 channel high resolution electrogastrogram (HR-EGG)|DIAGNOSTIC_TEST: Magnetogastrogram (MGG)|DIAGNOSTIC_TEST: Electrocardiogram (EKG)|DRUG: Ondansetron|DRUG: Cyproheptadine Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Feasibility Study of Octreotide Infusion During Liver Transplant.
Status: ACTIVE_NOT_RECRUITING
Conditions: Liver Transplantation|Renal Failure
Interventions: DRUG: Octreotide Acetate|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER