pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Expanding and Promoting Alternative Care and kNowledge in Decision-making Trial
Status: NOT_YET_RECRUITING
Conditions: Chronic Kidney Disease
Interventions: BEHAVIORAL: Educate and Engage|BEHAVIORAL: Educate and Engage Plus Kidney Supportive Care Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Information Support Using an Online Learning Platform for Malaysian Pediatric Leukemia and Lymphoma Parents
Status: COMPLETED
Conditions: Pediatric Acute Myeloid Leukemia|Pediatric Acute Lymphoid Leukemia|Pediatric Non-Hodgkin Lymphoma|Pediatric Hodgkin Lymphoma
Interventions: OTHER: eHOPE|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Combined Effect of CFTR Protein Modulator Drugs and Exercise in Cystic Fibrosis
Status: WITHDRAWN
Conditions: Cystic Fibrosis in Children
Interventions: BEHAVIORAL: Exercise|BEHAVIORAL: Unsupervised exercise|DRUG: CFTR Modulators
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of REMO Training for Hand Motor Recovery After Stroke
Status: RECRUITING
Conditions: Stroke|Stroke, Ischemic|Stroke Hemorrhagic|Stroke Sequelae
Interventions: DEVICE: REMO|OTHER: Task-Oriented Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multicenter, Nonrandomized, Prospective Study of Pulmonary Embolism Removal With the AngioJet 6F Ultra System
Status: TERMINATED
Conditions: Pulmonary Embolism
Interventions: DEVICE: AngioJet Ultra PE Thrombectomy System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fractional Radiofrequency for the Treatment and Reduction of Acne Scars and Wrinkles
Status: COMPLETED
Conditions: Acne Scars - Mixed Atrophic and Hypertrophic|Wrinkle
Interventions: DEVICE: Venus Viva
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Attention Retraining for Anxiety Disorder Patients Resistent to Antidepressants
Status: UNKNOWN
Conditions: Generalized Anxiety Disorder|Social Anxiety Disorder|Panic Disorder
Interventions: OTHER: Attentional Bias Modification Treatment (ABMT) - Active|OTHER: Attentional Bias Modification Treatment - Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: tDCS to Treat Subacute Aphasia
Status: WITHDRAWN
Conditions: Aphasia|Stroke, Acute
Interventions: DEVICE: Transcranial Direct Current Stimulation (tDCS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Medtronic Deep Brain Stimulation (DBS) Therapy for Epilepsy Post-Approval Study (EPAS)
Status: RECRUITING
Conditions: Epilepsy
Interventions: DEVICE: Activa™ PC and Percept™ PC Neurostimulation Systems
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I Study of Olaparib and Temozolomide for Ewings Sarcoma or Rhabdoomyosarcoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Ewing Sarcoma|Rhabdomyosarcoma
Interventions: DRUG: Olaparib|DRUG: Temozolomide|DRUG: Irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Peanut Allergy Vaccine Study in Healthy and Peanut-allergic Adults
Status: COMPLETED
Conditions: Food Hypersensitivity|Hypersensitivity|Immediate Hypersensitivity|Peanut Hypersensitivity
Interventions: BIOLOGICAL: E. Coli-Encapsulated, Recombinant Modified Peanut Proteins Ara h 1, Ara h 2, and Ara h 3
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Direct Lysis of Staph Aureus Resistant Pathogen Trial of Exebacase
Status: TERMINATED
Conditions: Staphylococcus Aureus Bacteremia|Staphylococcus Aureus Endocarditis
Interventions: DRUG: Exebacase|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sialic Acid Supplementation in N-Acetylneuraminic Acid Synthase (NANS) Deficiency
Status: COMPLETED
Conditions: N-Acetylneuraminic Acid Storage Disease
Interventions: OTHER: Neu5Ac supplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aromatherapy Versus Gum Chewing on Preoperative Anxiety
Status: COMPLETED
Conditions: Anxiety
Interventions: OTHER: Aromatherapy|OTHER: Gum Chewing|OTHER: Controlled
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: S.K.A.T.E.: Safety of Keppra as Adjunctive Therapy in Epilepsy
Status: COMPLETED
Conditions: Epilepsy
Interventions: DRUG: Levetiracetam (Keppra)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Diagnosis of Color Power Doppler Combined Minimally Invasive Sampling for Endometrial Diseases
Status: UNKNOWN
Conditions: Endometrial Diseases
Interventions: DIAGNOSTIC_TEST: Voluson E8 (GE Medical Systems, USA), Minimally Invasive Endometrium Sampler
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Imetelstat as Maintenance Therapy After Initial Induction Chemotherapy in Non-small Cell Lung Cancer (NSCLC)
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: imetelstat|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: tPA by Endovascular Administration for the Treatment of Submassive PE Using CDT for the Reduction of Thrombus Burden
Status: COMPLETED
Conditions: Pulmonary Embolism
Interventions: DEVICE: The Bashir™ Endovascular Catheter|DRUG: r-tPA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Lifestyle Intervention Among Patients With Hypertension or High-normal Blood Pressure
Status: UNKNOWN
Conditions: Hypertension|High-normal Blood Pressure
Interventions: BEHAVIORAL: supervised lifestyle intervention|BEHAVIORAL: healthy lifestyle education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: VNS Prospective Neuromodulation of Autonomic, Immune and Gastrointestinal Systems
Status: RECRUITING
Conditions: Autoimmune Diseases|Epilepsy|Autonomic Dysfunction|Inflammatory Bowel Diseases
Interventions: DEVICE: Vagal nerve stimulation (VNS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Randomized, Double-Blind, Placebo-Controlled Study of Gastroesophageal Reflux Disease Therapy.
Status: UNKNOWN
Conditions: Asthma
Interventions: DRUG: Lansoprazole; Solutab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Value of Myomectomy in Women With Intramural Myoma Before IVF.
Status: UNKNOWN
Conditions: Fibroid Uterus|IVF
Interventions: PROCEDURE: Open myomectomy|DRUG: Gonadotropins|DRUG: Human chorionic gonadotropin|PROCEDURE: Ovum pick up|PROCEDURE: Embryo transfer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating GS-9620 in Treatment Naive Subjects With Chronic Hepatitis C
Status: COMPLETED
Conditions: Hepatitis C
Interventions: DRUG: Single Ascending Dose Cohorts GS-9620|DRUG: Multiple Ascending Dose Cohorts GS-9620
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of 18F-DCFPyL PET/CT Imaging in Patients With Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: 18F-DCFPyL Injection|DIAGNOSTIC_TEST: PET/CT imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: RCT on Effectiveness of Oral Health Preventive Programmes in School Children in Uganda
Status: NOT_YET_RECRUITING
Conditions: Dental Caries|Dental Plaque|Dental Diseases|Dental Caries in Children|Oral Disease|Oral Manifestations
Interventions: BEHAVIORAL: Use of toothbrush/toothpaste/fluoride varnish|BEHAVIORAL: Education on nutrition/oral hygiene
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Introperative Ketamine and Lidocaine Infusion on Postoperative Opioid Consumption in Posterior Spinal Fusion Surgery
Status: COMPLETED
Conditions: Spine Fusion|Postoperative Pain
Interventions: DRUG: Ketamine|DRUG: Lidocain|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Sealing Molars: Split-mouth Randomized Clinical Trial
Status: UNKNOWN
Conditions: Dental Caries
Interventions: PROCEDURE: High cost|PROCEDURE: Low Cost
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Olanzapine for the Prevention of Chemotherapy Induced Nausea and Vomiting in Gynecologic Oncology Patients
Status: TERMINATED
Conditions: Gynecologic Cancer
Interventions: DRUG: Ondansetron|DRUG: Dexamethasone|DRUG: Neurokinin-1 Receptor Antagonist (NK1-RA)|DRUG: Olanzapine|DRUG: Compazine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Neoadjuvant Radiohormonal Therapy for Oligometastatic Prostate Cancer
Status: NOT_YET_RECRUITING
Conditions: Oligometastatic Prostate Carcinoma
Interventions: DRUG: ADT combined with abiraterone|RADIATION: neoadjuvant hormone and RT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neuramis® Volume Lidocaine Treatment in Patients With Loss of Mid-face Volume
Status: COMPLETED
Conditions: Aging
Interventions: DEVICE: Neuramis® Volume Lidocaine|DEVICE: Juvederm® Voluma® with Lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Indacaterol in Symptomatic COPD Patients With Low Risk of Exacerbations
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Indacaterol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Combination of Pegylated Interferon Alfa Plus Valopicitabine in Patients With Hepatitis C
Status: COMPLETED
Conditions: Chronic Hepatitis C
Interventions: DRUG: valopicitabine|DRUG: Pegylated Interferon Alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single Session Intervention to Prevent Common Mental Disorders and Among College Students
Status: COMPLETED
Conditions: Depression, Anxiety
Interventions: BEHAVIORAL: Growth Mindset and Modifiable Risk Factor Information|BEHAVIORAL: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Antithymocyte Globulin in Treating Patients Undergoing Stem Cell Transplant for Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma and Plasma Cell Neoplasm
Interventions: BIOLOGICAL: anti-thymocyte globulin
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Conformal High Dose Intensity Modulated Radiation Therapy for Disease to Thoracic and Lumbar Spine
Status: TERMINATED
Conditions: Vertebral Metastasis
Interventions: RADIATION: Conformal High Dose Intensity Modulated Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chidamide Combined With Cisplatin in Head and Neck Adenoid Cystic Carcinoma (HNACC)
Status: COMPLETED
Conditions: Adenoid Cystic Carcinomas|Cisplatin
Interventions: DRUG: Chidamide combined with cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Low LEVel TrAgus STimulation on the Electrophysiological Substrate of Patients With Ischemic CardioMyopathy Substrate of Subjects With Ischemic CardioMyopathy
Status: COMPLETED
Conditions: Ischemic Cardiomyopathy
Interventions: DEVICE: Low level tragus stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Whole-Brain Radiation Therapy or Stereotactic Radiosurgery With or Without Lapatinib Ditosylate in Treating Patients With Brain Metastasis From HER2-Positive Breast Cancer
Status: COMPLETED
Conditions: HER2-Positive Breast Carcinoma|Invasive Breast Carcinoma|Metastatic Malignant Neoplasm in the Brain|Recurrent Breast Carcinoma|Stage IV Breast Cancer AJCC v6 and v7
Interventions: OTHER: Laboratory Biomarker Analysis|DRUG: Lapatinib Ditosylate|RADIATION: Stereotactic Radiosurgery|RADIATION: Whole-Brain Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I/II Study of Different Doses and Dose Schedules of Milatuzumab (hLL1) in CLL
Status: COMPLETED
Conditions: Chronic Lymphocytic Lymphoma
Interventions: BIOLOGICAL: milatuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Autologous CAR-T Cells Targeting B7-H3 in TNBC iC9-CAR.B7-H3 T Cells
Status: RECRUITING
Conditions: Breast Cancer|Relapse|Resistant Cancer|Triple Negative Breast Cancer
Interventions: BIOLOGICAL: iC9-CAR.B7-H3 T Cell Therapy|DRUG: cyclophosphamide|DRUG: fludarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Anlotinib Combined With Docetaxel in Non-Driver Mutation Non-squamous NSCLC: the Save Study
Status: RECRUITING
Conditions: Non-Squamous Non Small Cell Lung Cancer
Interventions: DRUG: Anlotinib and Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cysteamine Bitartrate Delayed-Release for the Treatment of NAFLD in Children
Status: COMPLETED
Conditions: Nonalcoholic Fatty Liver Disease (NAFLD)
Interventions: DRUG: DR cysteamine bitartrate capsule|OTHER: DR cysteamine bitartrate placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Wayne State Warriors Marijuana Clinical Research Program: Cannabinoid Adjunct to Prolonged Exposure & Recovery
Status: NOT_YET_RECRUITING
Conditions: PTSD|Post Traumatic Stress Disorder
Interventions: DRUG: Cannabidiol (CBD) only|DRUG: Placebo only|DRUG: Delta-9-tetrahydrocannabinol (THC) only|DRUG: THC:CBD 1:1|DRUG: THC:CBD 1:10
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Bacteriostatic Normal Saline Versus Lidocaine for Intradermal Anesthesia
Status: COMPLETED
Conditions: Chronic Pain
Interventions: DRUG: Bacteriostatic Normal Saline|DRUG: 1% Lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Fidaxomicin to Prevent Clostridium Difficile Colonization
Status: WITHDRAWN
Conditions: Clostridium Difficile Infection
Interventions: DRUG: Fidaxomicin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Chemoembolization Using LifePearl Polyethylene Glycol Drug Eluting Microspheres With Doxorubicin in HCC
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma
Interventions: DEVICE: Chemoembolization Using LifePearl|DRUG: Doxorubicin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Suprazygomatic Nerve Block vs Surgical Site Infiltration in Cleft Palate Repair
Status: UNKNOWN
Conditions: Cleft Palate Children|Block
Interventions: OTHER: suprazygomatic maxillary nerve block|OTHER: surgical site infiltration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Central Serous Chorioretinopathy Treated by Modified Photodynamic Therapy
Status: COMPLETED
Conditions: Central Serous Chorioretinopathy
Interventions: DRUG: Verteporfin PDT, half-dose|DRUG: verteporfin PDT, half-fluence
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neurological Effects of Acupuncture to Prevent Radiation-induced Xerostomia
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: BEHAVIORAL: Questionnaires|PROCEDURE: Acupuncture|PROCEDURE: Electroencephalogram (EEG)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Early Dyadic Psychotherapy for Mothers Suffering From PPD on Oxytocin Level and on Childrens' Emotional Development
Status: UNKNOWN
Conditions: Postpartum Depression
Interventions: BEHAVIORAL: dyadic psychotherapeutic intervention|BEHAVIORAL: supportive intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CARNet : Self-Monitoring and Co-driving in Rheumatology With Internet : Rheumatoid Arthritis Cohort (Usual Care Study)
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: OTHER: SANOIA Website
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: Multifunctional Nutrition Tube in Dysphagia for Nasopharyngeal Carcinoma
Status: NOT_YET_RECRUITING
Conditions: Dysphagia
Interventions: DEVICE: Intermittent Oral-esophageal Tube Feeding|DEVICE: Nasogastric Tube Feeding|BEHAVIORAL: comprehensive rehabilitation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Evaluation Pilot Study of the Efficacy of Blink® Tears Lubricant Eye Drops for the Relief of Dry Eye Symptoms Following Implantation of Tecnis® Multifocal Introcular Lens
Status: COMPLETED
Conditions: Dry Eye
Interventions: DRUG: No topical artificial tear|DRUG: Blink® Tears Lubricant Eye Drops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combined TMS and Brief Cognitive Behavioral Therapy to Reduce Suicide
Status: COMPLETED
Conditions: Suicide
Interventions: DEVICE: Transcranial Magnetic Stimulation|OTHER: Brief Cognitive Behavioral Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Molecular Imaging of HER2 Expression in Breast Cancer Using [99mTc]Tc-G3-(G3S)3C Before Chemo/Targeted Therapy
Status: ENROLLING_BY_INVITATION
Conditions: Breast Cancer Female
Interventions: DRUG: [99mTc]Tc-G3-(G3S)3C
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Injectable Platelet Rich Fibrin on Healing and Patient Satisfaction Following Laser Gingival Depigmentation
Status: COMPLETED
Conditions: Gingival Pigmentation
Interventions: BIOLOGICAL: i-PRF|PROCEDURE: Diode Laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The CUSA Clarity Soft Tissue Removal Study
Status: COMPLETED
Conditions: Benign, Malignant Tumors or Other Soft Tissue Removal|Nephrectomy or Partial Nephrectomy With Parenchyma Removal
Interventions: DEVICE: CUSA Clarity Ultrasonic Surgical Aspirator System use
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Evening Dose of Immediate Release Methylphenidate on Sleep in Children With ADHD
Status: TERMINATED
Conditions: Attention Deficit Disorder With Hyperactivity|Behavioral Insomnia of Childhood
Interventions: DRUG: Immediate Release Methylphenidate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Intermittent Epidural Bolus on Fever During Labor Analgesia
Status: UNKNOWN
Conditions: Labor Pain|Pain|Neurologic Manifestations|Signs and Symptoms|Pathological Conditions, Signs and Symptoms
Interventions: PROCEDURE: Epidural analgesia|PROCEDURE: Combined spinal-epidural analgesia|PROCEDURE: Continuous epidural infusion|PROCEDURE: Intermittent epidural bolus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of URG101 in Painful Bladder Syndrome and Interstitial Cystitis
Status: TERMINATED
Conditions: Painful Bladder Syndrome|Interstitial Cystitis|Bladder Pain Syndrome
Interventions: DRUG: URG101|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ganciclovir Pharmacokinetics in Patients Undergoing Continuous Renal Replacement Therapy
Status: TERMINATED
Conditions: Acute Renal Failure|Cytomegalovirus Infections|Multi Organ Failure
Interventions: DRUG: intravenous (IV) ganciclovir
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Incidence and Severity of Drug Interactions Before and After Switching Antiretroviral Therapy to Bictegravir/Emtricitabine/Tenofovir Alafenamide in Treatment Experienced Patients
Status: COMPLETED
Conditions: HIV/AIDS
Interventions: DRUG: bictegravir/emtricitabine/tenofovir alafenamide
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study on Analgesia of GIC-1001 & GIC-1002 on Visceral Pain, Rectal Sensory Threshold Using the Barostat Method
Status: COMPLETED
Conditions: Pain|Cancer|Colonic Disease
Interventions: DRUG: GIC-1001 375 mg TID|DRUG: GIC-1001 500 mg TID|DRUG: GIC-1002 345 mg TID (equimolar to GIC-1001 375 mg TID)|DRUG: GIC-1002 460 mg (equimolar to GIC-1001 500 mg)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prophylactic Fenestration of the Peritoneum in Kidney Transplantation
Status: COMPLETED
Conditions: Incidence of Symptomatic Lymphocele After Kidney Transplantation|Prevalence of Perirenal Fluid Collections at One, Five and Ten Weeks
Interventions: PROCEDURE: Fenestration|PROCEDURE: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Human Recombinant Interferon Gamma-1b for the Prevention of Hospital-acquired Pneumonia in Critically Ill Patients: a Double-blind, International, Phase 2, Randomized, Placebo-controlled Trial - the PREV-HAP Study
Status: UNKNOWN
Conditions: Critically Ill Patients
Interventions: DRUG: Recombinant Interferon gamma 1b (IMUKIN®)|DRUG: Recombinant Interferon gamma 1b placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: VR Intervention to Improve Police Safety
Status: COMPLETED
Conditions: Autism Spectrum Disorder|Autism
Interventions: BEHAVIORAL: Virtual Reality Intervention|BEHAVIORAL: Video Modeling Intervention|BEHAVIORAL: No intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Individualized Positive End-Expiratory Pressure (PEEP) on Oxygenation, Hemodynamics, and Early Postoperative Atelectasis in Laparoscopic Bariatric Surgery
Status: RECRUITING
Conditions: Positive End-expiratory Pressure|Hemodynamic Variable|Postoperative Atelectasis|Laparoscopic Bariatric Surgery
Interventions: OTHER: Positive end-expiratory pressure 5 (PEEP 5)|OTHER: Individualized positive end-expiratory pressure (PEEPIND)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of CRT, Durvalumab and Surgery for SST
Status: NOT_YET_RECRUITING
Conditions: Superior Sulcus Tumor|Non-small Cell Lung Cancer Stage IIB|Non Small Cell Lung Cancer Stage III
Interventions: DRUG: Cisplatin|DRUG: S1|RADIATION: concurrent radiotherapy|DRUG: Durvalumab|PROCEDURE: Surgery|DRUG: Durvalumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare Effectiveness and Safety of Darunavir/Ritonavir (DRV/Rtv) 800mg/100mg Once Daily Versus DRV/Rtv 600mg/100mg Twice Daily in Early Treatment-Experienced HIV-1 Infected Patients (ODIN)
Status: COMPLETED
Conditions: Human Immunodeficiency Virus - Type 1
Interventions: DRUG: Darunavir (DRV)|DRUG: Ritonavir (rtv)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase IV Long-term Maintenance Study of Aripiprazole in the Treatment of Irritability Associated With Autistic Disorder
Status: COMPLETED
Conditions: Irritability Associated With Autistic Disorder
Interventions: DRUG: Aripiprazole|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Thoracal Paravertebral Block on Seroma Reduction in Breast Surgery
Status: COMPLETED
Conditions: Seroma|Breast Cancer
Interventions: PROCEDURE: Thoracal paravertebral block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Preterm Infants REtinalMicrovascular Alterations by Means of OCT Angiography
Status: NOT_YET_RECRUITING
Conditions: Premature With Dysplasia Bronchopulmonary|Premature Without Dysplasia Bronchopulmonary|Controls Born at Term
Interventions: DEVICE: OCT Angiography
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Vaccine Therapy and GM-CSF in Treating Patients With Acute Myeloid Leukemia in Remission
Status: UNKNOWN
Conditions: Leukemia
Interventions: BIOLOGICAL: PR1 leukemia peptide vaccine|BIOLOGICAL: sargramostim|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: A Phase Ib/II Study of GT90001 Combined With KN046 in Solid Tumors
Status: RECRUITING
Conditions: Solid Tumor
Interventions: DRUG: GT90001+KN046|DRUG: GT90001+KN046|DRUG: GT90001/KN046|DRUG: GT90001+KN046|DRUG: GT90001+KN046
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reducing Port Access Pain and Clinic Wait Time: An Evaluation of EMLA Cream Versus nüm™ Vapocoolant Spray
Status: ENROLLING_BY_INVITATION
Conditions: Pediatric Cancer
Interventions: DRUG: Num Vapocoolant Spray|DRUG: EMLA Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Ex Vivo Intraarterial Methylene Blue Injection Improve Nodal Staging Accuracy in Colorectal Cancer
Status: UNKNOWN
Conditions: Lymph Node Metastases|Colorectal Cancer
Interventions: OTHER: Methylene blue injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Vildagliptin on Left Ventricular Function in Patients With Type 2 Diabetes and Congestive Heart Failure
Status: COMPLETED
Conditions: Congestive Heart Failure|Type II Diabetes Mellitus
Interventions: DRUG: vildagliptin|DRUG: placebo of vildagliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Fibrinogen in the Initial Resuscitation of Severe Trauma (FiiRST)
Status: COMPLETED
Conditions: Trauma|Injury|Bleeding|Haemorrhage|Coagulopathy
Interventions: DRUG: Fibrinogen concentrate|DRUG: Placebo Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ROtational Atherectomy, Lithotripsy or LasER for the Treatment of CAlcified STEnosis
Status: UNKNOWN
Conditions: Coronary Artery Disease
Interventions: DEVICE: Percutaneous coronary Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Melatonin for Prevention of Postoperative Delirium After Lower Limb Fracture Surgery in Elderly Patients
Status: RECRUITING
Conditions: Orthopedic Surgery
Interventions: DRUG: Melatonin 4 mg|DRUG: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Immunogenicity and Safety of Heterologous and Homologous Boosting With ChAdOx1-S and CoronaVac or a Formulation of SCB-2019 (COVID-19)
Status: UNKNOWN
Conditions: Covid19
Interventions: BIOLOGICAL: ChAdOx1-S COVID-19 Vaccine(Fiocruz/Oxford-AstraZeneca)|BIOLOGICAL: CoronaVac (Sinovac Biotech)|BIOLOGICAL: Adjuvanted Recombinant SARS-CoV-2 TrimericS-protein Subunit Vaccine (SCB-2019 - Clover)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Continuous Spinal Anesthesia in Renal Transplantation
Status: ACTIVE_NOT_RECRUITING
Conditions: Renal Failure Chronic|Transplant;Failure,Kidney|Anesthesia
Interventions: PROCEDURE: Continuous spinal anesthesia|PROCEDURE: General anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of High-dose Dual Therapy and Bismuth Quadruple Therapy for Helicobacter Pylori Eradication on Intestinal Microecology
Status: RECRUITING
Conditions: Gastritis|Dyspepsia|Helicobacter Pylori Infection|Gastric Cancer|Peptic Ulcer
Interventions: DRUG: Esomeprazole|DRUG: Amoxicillin|DRUG: Bismuth|DRUG: Esomeprazole|DRUG: Amoxicillin|DRUG: Clarithromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Essential Amino Acid Supplementation for Femoral Fragility Fractures
Status: RECRUITING
Conditions: Femoral Fracture|Fragility Fracture|Muscle Atrophy
Interventions: COMBINATION_PRODUCT: Essential Amino Acid Supplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study in Healthy Young Men to Look at What Drives the Cardiovascular Effects After Dosing With Mirabegron.
Status: COMPLETED
Conditions: Healthy Volunteers|Pharmacodynamics of Mirabegron
Interventions: DRUG: mirabegron|DRUG: Bisoprolol|DRUG: propranolol|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Scapular PNF Versus Shoulder Strengthening Exercises in Patients With Lateral Epicondylitis.
Status: RECRUITING
Conditions: Lateral Epicondylitis
Interventions: OTHER: Scapular PNF|OTHER: Shoulder strengthening exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Biodegradable and Titanium Fixation Systems in Mandibular Symphysis or Parasymphysis Solitary Fractures
Status: APPROVED_FOR_MARKETING
Conditions: Mandible Fracture|Rigid Internal Fixation|Three-dimensional Finite Element
Interventions: OTHER: Biodegradable and titanium fixation used in mandibular fractures.
Study Type: EXPANDED_ACCESS
Clinical trial: 3K3A-APC for Treatment of Amyotrophic Lateral Sclerosis (ALS)
Status: COMPLETED
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DRUG: 3K3A-APC Protein
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Porcelain-fused-to-metal Versus Zirconia Implant- Supported in Mandibular Kennedy Class II
Status: RECRUITING
Conditions: Partial Edentulism Class II|Dental Implants|Implant
Interventions: DEVICE: Cobalt Chromium Removable Partial Denture|DEVICE: Implant-Supported Porcelain-Fused-to-Metal-Fixed Partial Denture|DEVICE: Implant-Supported Zirconia Fixed Partial Denture.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Live Birth Rate After Sperm Selection Using ZyMōt Multi (850µL) Device for Intra Uterine Insemination
Status: RECRUITING
Conditions: Infertility|Fertility Disorders
Interventions: DEVICE: ZyMōt Multi (850µL)|OTHER: Density Gradient Centrifugation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of a Program for Physical Activity and Healthy Eating Promotion in Hypertensives
Status: COMPLETED
Conditions: Hypertension
Interventions: BEHAVIORAL: VAMOS program - Active life improving health
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Controlled Clinical Study of Dupilumab in Patients With Bilateral Nasal Polyps
Status: COMPLETED
Conditions: Chronic Rhinosinusitis Phenotype With Nasal Polyps (CRSwNP)
Interventions: DRUG: Dupilumab SAR231893 (REGN668)|DRUG: Placebo|DRUG: Mometasone furoate 50 micrograms
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Clinical Study in Subjects With Primary Progressive Multiple Sclerosis to Assess the Efficacy, Safety and Tolerability of Two Oral Doses of Laquinimod Either of 0.6 mg/Day or 1.5mg/Day (Experimental Drug) as Compared to Placebo
Status: COMPLETED
Conditions: Primary Progressive Multiple Sclerosis
Interventions: DRUG: Placebo|DRUG: Laquinimod|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Observation or Radiation Therapy in Treating Patients With Newly Diagnosed Grade II Meningioma That Has Been Completely Removed by Surgery
Status: RECRUITING
Conditions: Grade II Meningioma|Intracranial Meningioma
Interventions: OTHER: Clinical Observation|RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Group Intervention for Improving Stigma Coping and Empowerment of People With Mental Illness (STEM)
Status: COMPLETED
Conditions: Schizophrenia|Depression
Interventions: BEHAVIORAL: psychotherapeutic STEM modules|BEHAVIORAL: Interventional control of normal psychoeducational treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tislelizumab Plus TP as Neoadjuvant Therapy for Local Advanced Cervical Carcinoma
Status: UNKNOWN
Conditions: Cervical Squamous Cell Carcinoma
Interventions: DRUG: Tislelizumab, paclitaxel/docetaxel, cisplatin/carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PREdisposition Genetical in Cardiac Insufficiency = Genetic Predisposition to Heart Failure
Status: TERMINATED
Conditions: ST Elevation (STEMI) Myocardial Infarction of Other Sites
Interventions: OTHER: Cohort
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Leucine Enriched Essential Amino Acid Mixture to Reverse Muscle Loss in Cirrhosis
Status: RECRUITING
Conditions: Cirrhosis, Liver
Interventions: DIETARY_SUPPLEMENT: Leucine enriched essential amino acid (EEA/LEU)|DIETARY_SUPPLEMENT: Balanced amino acid supplement (BAA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Sintilimab Combined With Chemotherapy and SBRT in Limited Metastatic Head and Neck Squamous Cell Carcinoma (LM-HNSCC)
Status: NOT_YET_RECRUITING
Conditions: Head and Neck Squamous Cell Carcinoma|Metastases|Immunotherapy|Stereotactic Body Radiotherapy
Interventions: DRUG: Sintilimab|RADIATION: SBRT|DRUG: Platinum based chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Simulated Walking With Multiplexing Prism for Field Expansion in Monocular Vision
Status: RECRUITING
Conditions: One Eye Blindness|Blind Left Eye|Blind Right Eye
Interventions: DEVICE: Multiplexing Prism
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy of Closed-Loop Strategy With and Without a Learning Component in Children and Adolescents With Type 1 Diabetes at a Diabetes Camp
Status: COMPLETED
Conditions: Diabetes|Type 1 Diabetes Mellitus
Interventions: DEVICE: Artificial Pancreas
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Lumbar Plexus Block Application in Ultrasound-guided Shamrock Method
Status: NOT_YET_RECRUITING
Conditions: Femoral Neck Fractures|Lumbosacral Plexus|Nerve Block
Interventions: PROCEDURE: in-plane needle guidance|PROCEDURE: out-of-plane needle guidance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Effect of Adding Ketamine Versus Dexmedetomidine to Bupivacaine in Pec 11 Modified Block on Postoperative Pain Control in Patients Undergoing Breast Surgery
Status: COMPLETED
Conditions: More Effective Postoperative Analgesia After Modified Radical Mastectomy With Better Drug Combination|More Prolonged Duration of Postoperative Analgesia After Modified Radical Mastectomy With Better Drug Combination
Interventions: PROCEDURE: Modified pec11 trunk block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Comparative Analysis of Outcome Between Extravesical and Transvesical Repair for Vesico-vaginal Fistula
Status: COMPLETED
Conditions: Vesico Vaginal Fistula
Interventions: PROCEDURE: Extravesical VVF repair
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Letrozole With or Without BYL719 or Buparlisib, for the Neoadjuvant Treatment of Postmenopausal Women
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: alpelisib|DRUG: buparlisib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of empagliFlozin on myocardIal metabOlic Rate of glucosE Estimated Through 18FDG PET (FIORE Study)
Status: COMPLETED
Conditions: Type 2 Diabetes|Cardiovascular Risk Factor
Interventions: DRUG: Empagliflozin 10 MG|DRUG: Glimepiride 2 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Effectiveness and Safety of Breeded Leech for Symptomatic Primary Arthrosis of the First Carpometacarpal Joint
Status: TERMINATED
Conditions: Rhizarthrosis
Interventions: BIOLOGICAL: Leeches|DRUG: Diclofenac
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Efficacy and Safety of a Prospective, Multicenter Drug Coated Balloon for Left Main Artery Disease in China
Status: UNKNOWN
Conditions: Coronary Diseases|Left Main Coronary Artery Disease|Bifurcation Lesions
Interventions: PROCEDURE: DCB
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Tolerability of Adjuvant Cisplatin/Docetaxel in Completely Resected Stage IB/II Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: cisplatin/docetaxel|DRUG: cisplatin/vinorelbine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Cell Response in the Tear Film After Overnight Contact Lens Wear
Status: COMPLETED
Conditions: White Blood Cells
Interventions: DEVICE: Lotrafilcon A contact lens|DEVICE: Lotrafilcon B contact lens|DEVICE: Clear Care Cleaning and Disinfection Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Ofatumumab and Bendamustine for Previously Treated Chronic Lymphocytic Leukemia (CLL)
Status: TERMINATED
Conditions: Chronic Lymphocytic Leukemia|Small Lymphocytic Lymphoma
Interventions: DRUG: Ofatumumab and Bendamustine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Open-label, Two-center, Randomized, Cross-over Study to Evaluate the Safety and Efficacy of Glycemic Control Using Hybrid-closed Loop vs. Advanced Hybrid Closed-loop in Young Subjects With Type 1 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: DEVICE: Medtronic Minimed 670G 3.0 HCL|DEVICE: Medtronic Minimed 670G 4.0 AHCL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gemcitabine and Split-Dose Cisplatin Plus Everolimus (RAD001) in Patients With Advanced Solid Tumor Malignancies
Status: COMPLETED
Conditions: Bladder Cancer|Renal Pelvis Cancer|Ureter Cancer
Interventions: DRUG: gemcitabine and split-dose cisplatin plus escalating doses of continuous Everolimus (RAD001)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PA3-17 Injection Treatment of Adult Patients With CD7-positive Relapsed/Refractory Lymphoid Hematologic Malignancies
Status: RECRUITING
Conditions: CD7-positive Relapsed/Refractory Lymphoid Hematologic Malignancies
Interventions: BIOLOGICAL: T cell injection targeting CD7 chimeric antigen receptor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Intermittent Bladder Catheterization (IBC) in Reducing Recurrence of Urethral Stricture
Status: NOT_YET_RECRUITING
Conditions: Urethral Stricture
Interventions: OTHER: Intermittent bladder catheterization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Phase 3, Bridging, Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel-group Trial to Evaluate the Efficacy and Safety of Subcutaneously Administered Bremelanotide in Premenopausal Women With Hypoactive Sexual Desire Disorder (With or Without Decreased Arousal)
Status: UNKNOWN
Conditions: Hypoactive Sexual Desire Disorder
Interventions: DRUG: Bremelanotide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of L-Ornithine-L-Aspartate in Cirrhotics With Hepatic Encephalopathy
Status: COMPLETED
Conditions: Hepatic Encephalopathy
Interventions: DRUG: L-Ornithine L-Aspartate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT