pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Low Dose Trimethoprim-Sulfamethoxazole for the Treatment of Pneumocystis Jirovecii Pneumonia
Status: NOT_YET_RECRUITING
Conditions: Pneumocystis|Pneumocystis Pneumonia|Pneumocystis Jirovecii Infection|Pneumocystis Infections|Pneumocystis Carinii Infection|Pneumocystosis; Pneumonia (Etiology)|Pneumocystis Carinii; Infection, Resulting From HIV Disease|Pneumocystosis Associated With AIDS
Interventions: DRUG: trimethoprim-sulfamethoxazole|DRUG: trimethoprim-sulfamethoxazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of Recombinant Anti-HER2 Humanized Monoclonal Antibody (GB221) for Injection
Status: UNKNOWN
Conditions: HER-2-positive Advanced Breast Cancer
Interventions: DRUG: GB221|DRUG: Placebo control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Efficacy and Safety of AVE5530 Co-administered With Atorvastatin in Primary Hypercholesterolemia
Status: TERMINATED
Conditions: Hypercholesterolemia
Interventions: DRUG: AVE5530|DRUG: atorvastatin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dexmedetomidine Versus Propofol for Sedation During Awake Endotracheal Intubation
Status: COMPLETED
Conditions: Sedation|Intubation
Interventions: DRUG: dexmedetomidine combined with midazolam and remifentanil.|DRUG: propofol combined with midazolam and remifentanil.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Difference Between Acupuncture and Far-infrared Ray Illumination at CV12 Acupoint
Status: COMPLETED
Conditions: Reaction of Autonomic Nervous System|Reaction of Acupuncture|Reaction of Far Infrared Ray
Interventions: PROCEDURE: acupuncture and far-infrared ray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety and Efficacy of Human Myeloid Progenitor Cells (CLT-008) During Chemotherapy for Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Acute Myeloid Leukemia|Neutropenia|Infection
Interventions: BIOLOGICAL: CLT-008|BIOLOGICAL: G-CSF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Gamma Entrainment Stimulation for Cognitive Dysfunction After aSAH
Status: NOT_YET_RECRUITING
Conditions: Subarachnoid Hemorrhage, Aneurysmal|Cognitive Dysfunction
Interventions: PROCEDURE: Gamma Entrainment Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of a Hybrid Model of Cardiac Rehabilitation on Patient Outcomes
Status: COMPLETED
Conditions: Cardiac Surgery|Coronary Artery Bypass Graft CABG|Stent|Valve Replacement
Interventions: OTHER: Exercise Component Of Cardiac Rehabilitation (Hybrid Model) Intensity Recovery Progression Protocol (IRPP)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of D-amphetamine on Reward Functioning
Status: COMPLETED
Conditions: Anhedonia
Interventions: DRUG: 10 mg d-amphetamine|DRUG: 20mg d-amphetamine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of Bevacizumab in Combination With Standard of Care Treatment in Participants With Advanced Non-squamous Non-small Cell Lung Cancer (NSCLC)
Status: COMPLETED
Conditions: Non-Squamous Non-Small Cell Lung Cancer
Interventions: DRUG: Bevacizumab|DRUG: Docetaxel|DRUG: Erlotinib|DRUG: Pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial On 4 Cycles Of Neoadjuvant Chemotherapy Plus Concurrent Chemoradiation In N2-3 Nasopharyngeal Carcinoma
Status: RECRUITING
Conditions: Nasopharyngeal Carcinoma
Interventions: DRUG: Docetaxel (DOC)|DRUG: Cisplatin (DDP)|RADIATION: Concurrent chemoradiation (CCRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Role of Prophylactic Metoclopramide With Tramadol in Trauma Patients
Status: COMPLETED
Conditions: Trauma|Opioid Analgesic Adverse Reaction
Interventions: DRUG: Tramadol|DRUG: Metoclopramide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy Study of Nifedipine Controlled-Release Tablets (Xin Ran) to Treat Early Morning Blood Pressure and Central Arterial Pressure
Status: UNKNOWN
Conditions: Essential Hypertension
Interventions: DRUG: nifedipine CR tablets (Xin Ran)|DRUG: Adalat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fascia Iliaca Compartment Block for Proximal-end Femur Fractures
Status: COMPLETED
Conditions: Proximal Femur Fractures
Interventions: DRUG: Placebo|DRUG: Bupivacaine|DEVICE: Ultrasound guided fascia iliaca compartment block|DRUG: Intrathecal medications (bupivacaine (15 mg) in conjunction with fentanyl 20 micrograms)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Inhaled Dose Analysis Using a Breath Actuated Nebulizer in Healthy Subjects
Status: RECRUITING
Conditions: Healthy Volunteers|Aerosol Therapy|Inhaled Drug Dose|Pharmacogenomic Drug Interaction
Interventions: DEVICE: Breath-actuated vibrating mesh nebulizer|DEVICE: Continuous vibrating mesh nebulizer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Efficacy and Safety of Probiotics Combined With Enteric-coated Budesonide Capsules in Patients With Primary IgA Nephropathy
Status: NOT_YET_RECRUITING
Conditions: Glomerulonephritis, IGA|Probiotics|Budesonide
Interventions: DRUG: probiotics combined with enteric-coated budesonide capsule|DRUG: probiotics placebo combined with enteric-coated budesonide capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: SBRT vs. Conventional Fractionation With HDR Boost for Prostate Cancer
Status: RECRUITING
Conditions: Prostate Cancer
Interventions: RADIATION: Sterotactic Body Radiotherapy|RADIATION: Conventionally Fractionated Radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hyperthermic Intraperitoneal Chemotherapy (HIPEC) : Predictive Marker and Mechanism
Status: TERMINATED
Conditions: Peritoneal Carcinomatosis
Interventions: BIOLOGICAL: peripheral venous blood samples
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Barley Bread and Metabolic Disease
Status: COMPLETED
Conditions: Metabolic Syndrome
Interventions: OTHER: Barley bread|OTHER: Wheat bread
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Cannabinoid Receptor Function & Alcoholism
Status: COMPLETED
Conditions: Alcoholism
Interventions: DRUG: THC|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Phase 1b/2 Study of Alvocidib Plus Decitabine or Azacitidine in Patients With MDS
Status: TERMINATED
Conditions: Myelodysplastic Syndromes (MDS)
Interventions: COMBINATION_PRODUCT: Alvocidib Plus Decitabine (during dose escalation only) or Azacitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stress and Medication Effects on Cocaine Cue Reactivity
Status: COMPLETED
Conditions: Cocaine Related Disorders
Interventions: DRUG: Guanfacine|DRUG: Modafinil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Lidocaine Infusion With ANI Monitoring in Spine Surgery.
Status: RECRUITING
Conditions: Spine Surgery
Interventions: DRUG: Lidocaine HCl 2%|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Olmutinib 600 mg QD in Patients With T790M-positive NSCLC After Treatment With an EGFR-TKI
Status: TERMINATED
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: Olmutinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gemcitabine, Cisplatin, and Sunitinib (GC-S) as Neoadjuvant Chemotherapy in Patients With Muscle-Invasive Bladder Cancer
Status: COMPLETED
Conditions: Bladder Cancer|Urinary Bladder
Interventions: DRUG: Sunitinib|DRUG: Gemcitabine|DRUG: cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BiPAP in Pediatric Moderate to Severe Asthma Randomized Control Trial
Status: RECRUITING
Conditions: Asthma in Children
Interventions: DEVICE: Bi-level Positive Airway Pressure|DEVICE: Sham Bi-level Positive Airway Pressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Comparison Between Co-phenylcaine Nasal Spray and Nasal Nebulization Prior to Rigid Nasoendoscopic Examination
Status: COMPLETED
Conditions: Anaesthesia|Rhinitis
Interventions: DEVICE: Nasal nebulisation into the right nostril|DEVICE: Nasal Spray into the right nostril
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study of ABT-652 in Adults With Osteoarthritis Pain of the Knee
Status: COMPLETED
Conditions: Osteoarthritis of the Knee
Interventions: DRUG: ABT-652|DRUG: Placebo|DRUG: Naproxen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Experiences and Health-related Quality of Life of Informal Caregivers of Dialysis Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Peritoneal Dialysis|Hemodialysis, Home|Hemodialysis|Quality of Life|Informal Caregivers|Family Caregivers|Renal Replacement Therapy|Kidney Failure, Chronic|Patient Reported Outcome Measures
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: When Should Low-dose Aspirin be Resumed After Peptic Ulcer Bleeding?
Status: UNKNOWN
Conditions: Aspirin|GastroIntestinal Bleeding
Interventions: OTHER: Resume Aspirin within 12 hours|OTHER: Resume Aspirin 72 - 84 hours
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: POL and Access Intervention to Reduce HIV Stigma Among Service Providers in China
Status: COMPLETED
Conditions: HIV-related Stigma|Patient Satisfaction|Provider-patient Interaction
Interventions: BEHAVIORAL: Cognitive behavioral sessions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Anabolic Effects of Intraoperative Feeding in Reconstruction Surgery
Status: COMPLETED
Conditions: Fasting|Feeding, Time Restricted|Stress-related Problem|Head and Neck Neoplasms|Catabolic State|Hyperglycemia Stress|Muscle Wasting|Complication,Postoperative
Interventions: DIETARY_SUPPLEMENT: Enteral nutrition formula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: The Use of Electrical Bioimpedance to Evaluate Dry Weight in Patients With Chronic Renal Failure in Hemodialysis
Status: COMPLETED
Conditions: Chronic Renal Failure|Dialysis|Dry Weight|Blood Pressure
Interventions: COMBINATION_PRODUCT: To estimate the dry weight of patients with chronic renal failure under hemodialysis treatment using BIVA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Clinical Study to Explore the Efficacy of ACT-129968 in Patients With Partly Controlled Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Placebo|DRUG: Setipiprant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CSII Versus MDI in Pregnant Women With Type 2 Diabetes
Status: UNKNOWN
Conditions: Type 2 Diabetes|Pregnancy in Diabetic
Interventions: DEVICE: Continuous subcutaneous insulin infusion (CSII)|DEVICE: Multiple daily insulin injection (MDI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ridge Preservation Comparing a Polylactic Acid Membrane vs. an Acellular Dermal Matrix Membrane
Status: COMPLETED
Conditions: Ridge Preservation
Interventions: PROCEDURE: Acellular dermal matrix membrane|PROCEDURE: Polylactic acid membrane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Sleep Apnea on Blood Pressure Control and Outcome Early After Subarachnoid Hemorrhage
Status: UNKNOWN
Conditions: Subarachnoid Hemorrhage|Sleep Apnea
Interventions: DEVICE: Sleep Apnea Screening (Out of Center Polysomnography Device)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Different Methods to Calculate Pendelluft by Electrical Impedance Tomography in Mechanically Ventilated Patients
Status: RECRUITING
Conditions: Asynchrony, Patient-Ventilator|ARDS|Respiratory Insufficiency|Respiratory Effort-Related Arousal &#X7C; Patient &#X7C; Respiratory Measures and Ventilator Management
Interventions: OTHER: Pressure Support Variation and Calculation of Respiratory Mechanics
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Bevacizumab Plus EGFR-TKIs in Chinese Patients With EGFR-mutant NSCLC: a Real-world Study
Status: UNKNOWN
Conditions: NSCLC
Interventions: DRUG: Bevacizumab|DRUG: Erlotinib|DRUG: Gefitinib|DRUG: Icotinib|DRUG: Afatinib|DRUG: Dacomitinib|DRUG: Osimertinib
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Multimodal Intervention in Allogeneic Stem Cell Transplantation
Status: COMPLETED
Conditions: Allogeneic Stem Cell Transplantation|Leukemia
Interventions: BEHAVIORAL: Multimodal exercise and psychosocial program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Curosurf/Budesonide for Infants With Respiratory Distress Syndrome
Status: COMPLETED
Conditions: Respiratory Distress Syndrome
Interventions: DRUG: Budesonide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mood Alterations in the Patients With Non-Muscle Invasive Bladder Cancer Treated With BCG
Status: RECRUITING
Conditions: Non-Muscle Invasive Bladder Cancer
Interventions: OTHER: Questionnaires|OTHER: Daily Mood Diaries|OTHER: Urine Specimen Collection|OTHER: Research Blood Draw|OTHER: Utilize excess tissue from a standard of care procedure
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: NAC Prevents Toxicity of Teeth Bleaching
Status: COMPLETED
Conditions: Removal of Toxicity From Dental Bleaching
Interventions: DIETARY_SUPPLEMENT: NAC|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Cognitive Behavior Therapy on Quality of Life in Paroxysmal Atrial Fibrillation Patients
Status: COMPLETED
Conditions: CBT
Interventions: BEHAVIORAL: Cognitive Behaviour Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Hyperlactatemia During and After Tumorcraniotomy
Status: COMPLETED
Conditions: Hyperlactatemia|Brain Tumor|Surgery|Anesthesia
Interventions: OTHER: Serum-lactate < 2,2 mmol/L|OTHER: Serum-lactate >/= 2,2 mmol/L
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Cabozantinib and Nivolumab in Metastatic Castration Resistant Prostate Cancer
Status: RECRUITING
Conditions: Castration-resistant Prostate Cancer|Metastatic Cancer
Interventions: DRUG: Cabozantinib|DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial to Reduce Cardiovascular Events With Aranesp® Therapy (TREAT)
Status: COMPLETED
Conditions: Kidney Disease|Diabetes Mellitus|Anemia
Interventions: DRUG: Placebo|DRUG: darbepoetin alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: BLI-800-302: BLI-800 vs an Active Control Bowel Preparation in Adult Subjects Undergoing Colonoscopy
Status: COMPLETED
Conditions: Colonoscopy
Interventions: DRUG: BLI-800|DRUG: Polyethylene glycol 3350 based bowel preparation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose:
Clinical trial: Interferon Alpha 2b Intensification in HIV-Positive Individuals on Antiretroviral Therapy
Status: COMPLETED
Conditions: HIV Infection
Interventions: DRUG: Pegylated Interferon Alpha 2b (PEGINTRON)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Co-Administration of AS03 Adjuvanted A/H7N9 IIV With IIV4
Status: COMPLETED
Conditions: Avian Influenza|Influenza|Influenza Immunisation
Interventions: DRUG: AS03|BIOLOGICAL: Inactivated influenza H7N9 vaccine|BIOLOGICAL: Influenza Virus Quadrivalent Inactivated Vaccine|OTHER: Phosphate Buffered Saline (PBS) diluent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Ropeginterferon Alfa 2b for Early Myelofibrosis
Status: RECRUITING
Conditions: Primary Myelofibrosis, Prefibrotic Stage|Myelofibrosis
Interventions: DRUG: Ropeginterferon alfa-2b
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Intensive Chiropractic Care to Usual Care for Adults With Spinal Cord Injuries.
Status: COMPLETED
Conditions: Spinal Cord Injuries
Interventions: OTHER: Sham intervention|OTHER: Chiropractic Care|OTHER: Physical therapy intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Testing a Personalized Normative Feedback Intervention for Vaccine Hesitancy
Status: RECRUITING
Conditions: COVID-19|Vaccine Hesitancy
Interventions: BEHAVIORAL: Vaccine Norms Feedback|BEHAVIORAL: Alcohol Norms Feedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Randomized Trial to Evaluate the Effectiveness of X-22 as a Smoking Cessation Aid
Status: COMPLETED
Conditions: Smoking Cessation
Interventions: DRUG: X-22 Smoking Cessation Product|DRUG: Active Control Cigarettes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of New Alcohol Free Mouthrinses
Status: COMPLETED
Conditions: Gum Disease
Interventions: OTHER: alcohol-free experimental mouth rinse|OTHER: alcohol-containing mouth rinsing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Trial to Evaluate Beta-Lactam Antimicrobial Therapy of Community Acquired Pneumonia in Children
Status: COMPLETED
Conditions: Pneumonia
Interventions: DRUG: Amoxicillin|DRUG: Amoxicillin-clavulanate|DRUG: Cefdinir|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: CD4-ZETA Gene Modified T Cells With and Without Exogenous Interleukin-2 (IL-2) In HIV Patients
Status: COMPLETED
Conditions: HIV-1 Infections
Interventions: DRUG: HAART|BIOLOGICAL: T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Etoposide in the First-line Treatment of Adult EBV-HLH
Status: UNKNOWN
Conditions: Hemophagocytic Lymphohistiocytosis
Interventions: DRUG: Etoposide|DRUG: Dexamethasone|DRUG: Etoposide|DRUG: IVIG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Roflumilast on Exacerbation Rate in Patients With Chronic Obstructive Pulmonary Disease (COPD): The HERMES Study (BY217/M2-125)
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: DRUG: Roflumilast|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of EVAR and ESAR for Infrarenal Aortic Aneurysms With a Wide Proximal Neck
Status: RECRUITING
Conditions: Aortic Aneurysm, Abdominal
Interventions: DEVICE: endovascular aneurysm repair (EVAR) using the Endurant II/IIs stent graft system|DEVICE: endosuture aneurysm repair (ESAR) using Heli-FX EndoAnchor system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability of Oral LCL161 in Japanese Adult Patients With Advanced Solid Tumors
Status: COMPLETED
Conditions: Neoplasms
Interventions: DRUG: LCL161|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Whole-body Stretching Exercise for Reducing Musculoskeletal Pain and Physical Exertion Among Healthcare Professionals
Status: COMPLETED
Conditions: Healthcare Professionals
Interventions: OTHER: whole body stretching excercise|OTHER: educational program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Injury Prevention Program on Cricketers
Status: COMPLETED
Conditions: Sports Physical Therapy
Interventions: OTHER: Experimental: warm up|OTHER: Experimental: cool down|OTHER: No intervention: control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Can Vitamin D Treatment Help Treat Moderate to Severe Atopic Dermatitis in Young Children? The D-Vex Pilot Study
Status: SUSPENDED
Conditions: Atopic Dermatitis
Interventions: DRUG: Stoss vitamin D|DRUG: Daily vitamin D|DRUG: Stoss placebo|DRUG: Daily placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acalabrutinib, Umbralisib, and Ublituximab for the Treatment of Previously Untreated Mantle Cell Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Mantle Cell Lymphoma
Interventions: DRUG: Acalabrutinib|BIOLOGICAL: Ublituximab|DRUG: Umbralisib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Combination of Sirolimus and Sutent in Patients With Advanced Solid Tumors Non-Curable With Standard Therapy
Status: TERMINATED
Conditions: Tumors
Interventions: DRUG: Sunitinib malate|DRUG: Rapamycin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Examining Brain Changes Using Functional Magnetic Resonance Imaging (fMRI) in Amputees With Phantom Limb Pain Following Mirror Therapy
Status: UNKNOWN
Conditions: Phantom Limb Pain
Interventions: DEVICE: mirror-box treatment|BEHAVIORAL: observation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Comparative Clinical Study of Gamisoyosan on Anxiety of Generalized Anxiety Disorder According to Dosage Form
Status: COMPLETED
Conditions: Generalized Anxiety Disorder
Interventions: DRUG: Placebo|DRUG: KyungBangn-Gamisoyosan-x-gwarip|DRUG: KyungBangn Gamisoyosan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of TY027, a Treatment for COVID-19, in Humans
Status: TERMINATED
Conditions: Coronavirus Disease-2019 (COVID-19)
Interventions: BIOLOGICAL: TY027|BIOLOGICAL: TY027|OTHER: 0.9% saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: ATP/AMP Challenge in Healthy Non-smokers, Smokers, Patients With Asthma, and Patients With Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Asthma|COPD|Smoking
Interventions: PROCEDURE: Inhalation Challenge with ATP|PROCEDURE: Inhalation Challenge with AMP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Radiofrequency Ablation in Treating Patients With Early Invasive Breast Cancer or Ductal Carcinoma in Situ
Status: COMPLETED
Conditions: Breast Cancer
Interventions: PROCEDURE: conventional surgery|PROCEDURE: neoadjuvant therapy|PROCEDURE: radiofrequency ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Feasibility and Efficacy of Vitamin D Supplementation in Women With Metastatic Breast Cancer (SAFE-D)
Status: COMPLETED
Conditions: Adult Women|Metastatic Breast Cancer|Estrogen Receptor Positive
Interventions: DRUG: Cholecalciferol
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Long-term Persistence of GlaxoSmithKline (GSK) Biologicals' Candidate Cytomegalovirus (CMV) Vaccine
Status: COMPLETED
Conditions: Infections, Cytomegalovirus
Interventions: PROCEDURE: Blood sampling|BIOLOGICAL: GSK149203A
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Impact of Forearm Free Flap in Orbital Exenteration Reconstruction
Status: UNKNOWN
Conditions: Cancer
Interventions: BEHAVIORAL: Comparative analysis comparing the morbidity of the antebrachial free flap to that of the temporal flap flap during exenteration as well as the rate of fitting patients with epithesis.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Immuno & Safety Study of GSK Biologicals' Thio or Preservative Free Hepatitis B Vaccine in Subjects Aged 11-15 Yrs
Status: COMPLETED
Conditions: Hepatitis B
Interventions: BIOLOGICAL: Engerix™-B (thiomersal-free) 20µg|BIOLOGICAL: 10 μg Engerix™-B (preservative-free)|BIOLOGICAL: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Collagen Peptides, in Combination With Resistance Training, on Body Composition and Muscle Strength in Untrained Men
Status: RECRUITING
Conditions: Body Composition|Lean Body Mass|Muscle Strength|Muscle Power
Interventions: DIETARY_SUPPLEMENT: Effect of collagen peptides, in combination with resistance training, on body composition and muscle strength compared to placebo in untrained men|DIETARY_SUPPLEMENT: Placebo Control intervention: Effect of resistance training in combination with placebo (silicon dioxide), on body composition and muscle strength in untrained men
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Ixekizumab in Adult Patients With Lichen Planus and Lichen Planopilaris
Status: COMPLETED
Conditions: Lichen Planus Scalp|Lichen Planus|Lichen Planopilaris
Interventions: DRUG: Ixekizumab Auto-Injector
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: FIRST-line Support for Assistance in Breathing in Children (FIRST-ABC) Feasibility Study
Status: COMPLETED
Conditions: Hypoxia|Respiratory Acidosis|Moderate/Severe Respiratory Distress
Interventions: DEVICE: Treatment strategy: Non-invasive respiratory support delivered via high flow nasal cannula|DEVICE: Treatment strategy: Non-invasive respiratory support delivered via continuous positive airway pressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Study to Assess Safety, Pharmacokinetics and Efficacy of SL-1002 for Limb Spasticity
Status: ACTIVE_NOT_RECRUITING
Conditions: Spasticity
Interventions: DRUG: SL-1002|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Complete Infarct Related Artery Revascularization
Status: TERMINATED
Conditions: Myocardial Infarction|Coronary Artery Disease
Interventions: PROCEDURE: IRA stenting in culprit lesion only|PROCEDURE: IRA stenting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Tolerability，Safety，PK/PD Study of rhTPO in the Patients With Liver Function Impairment
Status: UNKNOWN
Conditions: Liver Cirrhosis
Interventions: DRUG: Recombinant human thrombopoietin|DRUG: Recombinant human thrombopoietin|DRUG: Placebo|DRUG: Recombinant human thrombopoietin|DRUG: Placebo|DRUG: recombinant human thrombopoietin|DRUG: placebo|DRUG: Recombinant human thrombopoietin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective Study Investigating Aspirin and Intraoperative Blood Loss and Complications Following Inguinal Hernia Repair
Status: UNKNOWN
Conditions: Hernia, Inguinal|Postoperative Complications|Postoperative Hemorrhage
Interventions: DRUG: Aspirin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pembrolizumab and Binimetinib in Treating Patients With Locally Advanced or Metastatic Triple Negative Breast Cancer
Status: COMPLETED
Conditions: Breast Adenocarcinoma|Metastatic Triple-Negative Breast Carcinoma|Stage III Breast Cancer AJCC v7|Stage IIIA Breast Cancer AJCC v7|Stage IIIB Breast Cancer AJCC v7|Stage IIIC Breast Cancer AJCC v7|Stage IV Breast Cancer AJCC v6 and v7
Interventions: DRUG: Binimetinib|OTHER: Laboratory Biomarker Analysis|BIOLOGICAL: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of a Mechanical Gait Repetitive Training Technique in Hemiparetic Stroke Patients (AVC)
Status: TERMINATED
Conditions: Hemiplegia|Stroke
Interventions: DEVICE: Gait trainer|DEVICE: Conventional rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RCT - Assessing the Benefits of the Use of a Tension Night Splint in Patients With Plantar Fasciitis
Status: COMPLETED
Conditions: Plantar Fasciitis
Interventions: DEVICE: tension night splint|OTHER: standard practice - a structured rehabilitation programme
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Echocardiographic Screening of Pregnant Women During Antenatal Care
Status: RECRUITING
Conditions: Valvular Heart Disease|Rheumatic Heart Disease|Pregnancy Complications
Interventions: DIAGNOSTIC_TEST: Transthoracic echocardiography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of the Pharmacokinetics and Safety of Tasimelteon in Children and Adolescents
Status: COMPLETED
Conditions: Circadian Rhythm Sleep Disorders|Non-24 Hour Sleep-Wake Disorder|Autism Spectrum Disorder|Smith-Magenis Syndrome
Interventions: DRUG: tasimelteon
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bispectral Index-guided Sedation for Flexible Bronchoscopy
Status: COMPLETED
Conditions: Flexible Bronchoscopy
Interventions: DEVICE: Bispectral index guide propofol infusion|DRUG: Clinical-judged midazolam administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Electromyographic (EMG) Biofeedback Training in Zone I-III Flexor Tendon Injuries
Status: COMPLETED
Conditions: Flexor Tendon Rupture|Hand Therapy
Interventions: PROCEDURE: EMG biofeedback training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testing Immunotherapy Versus Observation in Patients With HPV Throat Cancer
Status: SUSPENDED
Conditions: Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8|Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8|Pathologic Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8|Pathologic Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8
Interventions: PROCEDURE: Biospecimen Collection|DRUG: Cisplatin|PROCEDURE: Computed Tomography|PROCEDURE: Echocardiography|OTHER: Fludeoxyglucose F-18|RADIATION: Intensity-Modulated Radiation Therapy|BIOLOGICAL: Nivolumab|OTHER: Patient Observation|PROCEDURE: Positron Emission Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reducing the Abuse Liability of Prescription Opioids
Status: COMPLETED
Conditions: Addiction
Interventions: DRUG: Risperidone|DRUG: Ziprasidone|DRUG: Oxycodone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety Study of FluarixTM Vaccine in Children Who Have Previously Been Vaccinated With PandemrixTM
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: FluarixTM|BIOLOGICAL: HavrixTM Junior (in subjects of 15 years old or below) or HavrixTM (in subjects above 15 years old)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of Suvorexant in Patients With Multiple Sclerosis Fatigue and Insomnia
Status: COMPLETED
Conditions: Multiple Sclerosis|Fatigue|Insomnia
Interventions: DRUG: Suvorexant|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Geriatric Recovery Using Inpatient and Post-hospitalization Supplementation
Status: RECRUITING
Conditions: Aging
Interventions: DIETARY_SUPPLEMENT: Whey Protein|DIETARY_SUPPLEMENT: Collagen Protein|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Intravenous Iron Metabolism in Restless Legs Syndrome
Status: COMPLETED
Conditions: Restless Legs
Interventions: DRUG: Ferric Carboxymaltose (FCM)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Eletriptan Pharmacokinetics In Korean Males
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Eletriptan commercial tablet|DRUG: Eletriptan commercial tablet|DRUG: Eletriptan commercial tablet|DRUG: Eletriptan commercial tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Intracoronary Thrombus Assessed by OFDI After Successful Fibrinolysis And Its Impact On Myocardial Reperfusion
Status: COMPLETED
Conditions: Myocardial Infarction|Intracoronary Thrombus
Interventions: DEVICE: optimal coherence tomography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phase II Docetaxel / Carboplatin / XRT + Surgical Resection in Stage III NSCLC
Status: TERMINATED
Conditions: Lung Cancer|Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: Docetaxel|DRUG: Carboplatin|PROCEDURE: Radiation therapy|PROCEDURE: Surgical resection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of DWC20155/DWC20156 Combination Therapy in Patients With Gastritis
Status: TERMINATED
Conditions: Gastritis
Interventions: DRUG: DWC20155|DRUG: DWC20156|DRUG: placebo of DWC20155|DRUG: placebo of DWC20156
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Electrical Impulse Parameters and Neuronal Population in the Cochlear Implanted Patient-PULSE
Status: NOT_YET_RECRUITING
Conditions: Sensorineural Hearing Loss
Interventions: OTHER: Cochlear implant (Oticon) stimulation parameter optimization
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Resorbable Polymer Plates in Repair of Blowout Orbital Floor Fractures
Status: UNKNOWN
Conditions: Post-Traumatic Orbital Deformity
Interventions: PROCEDURE: repair of orbital floor fractures using resorbable plates
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Increasing Adherence to Oral Appliance Therapy for Obstructive Sleep Apnea
Status: COMPLETED
Conditions: Obstructive Sleep Apnea|Adherence, Patient
Interventions: BEHAVIORAL: adherence promotion techniques|PROCEDURE: Routine Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Evaluate the Efficacy and Safety of MBA-P01 in Treatment of Glabellar Lines
Status: COMPLETED
Conditions: Glabellar Frown Lines
Interventions: DRUG: MBA-P01 (Botulinum toxin A)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Diabetic Foot Ulcer. Effectiveness of Chlorhexidine Gluconate 0.125 % Compared With Sterile Deionized Water
Status: COMPLETED
Conditions: Soft Tissue Infections
Interventions: PROCEDURE: chlorhexidine gluconate|OTHER: deionized water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of Vitamin D Supplementation in Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DIETARY_SUPPLEMENT: Cholecalciferol|DIETARY_SUPPLEMENT: Miglyol oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Multicentre Study on Diabetic Foot Treatment
Status: RECRUITING
Conditions: Diabetic Foot
Interventions: PROCEDURE: Tibial Transportation Combined With Autologous mesenchymal stem cells Local Infusion|PROCEDURE: Tibial Transportation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Robotic Brace Incorporating Electromyography for Moderate Affected Arm Impairment After Stroke
Status: COMPLETED
Conditions: Hemiparesis
Interventions: DEVICE: Myomo Robotic Arm|BEHAVIORAL: RTP Standard Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Meal Frequency and Timing on Insulin Dose and Clock Gene in Type 2 Diabetic Patients
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: OTHER: Breakfast Diet (Bdiet)|OTHER: 6Meal Diet (6Mdiet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Subcutaneous Amifostine (Ethyol®) in the Prevention of Radiochemotherapy-Induced Esophagitis and Pneumonitis in Patients With Unresectable Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Esophagitis|Pneumonitis|Non-Small Cell Lung Carcinoma
Interventions: DRUG: Amifostine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Post-op Rehabilitation's Influence on Tendon Healing & Clinical Outcomes Following Arthroscopic Rotator Cuff Repair
Status: COMPLETED
Conditions: Rotator Cuff Tear
Interventions: OTHER: Early Motion Protocol|OTHER: Immobilization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Back in the Game: a Smartphone Application to Support Athletes Returning to Sport After Serious Injury
Status: ACTIVE_NOT_RECRUITING
Conditions: Anterior Cruciate Ligament Injury
Interventions: BEHAVIORAL: Back in the Game|OTHER: Usual rehabilitation care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Water Intake on the State of Hydration and Renal Function in Elderly Patients
Status: UNKNOWN
Conditions: Renal Function Disorder
Interventions: OTHER: Guided water intake|OTHER: Placebo - free demand water intake
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Impact of Macronutrient Composition of Energy-restricted Diet and Exercise on Body Composition and Appetite Hormones.
Status: RECRUITING
Conditions: Gastrointestinal Hormones
Interventions: COMBINATION_PRODUCT: caloric restrction high carbohydrate low fat diet with exercise training program|COMBINATION_PRODUCT: caloric restrction high fat low carbohydrate diet with exercise training program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Lazertinib/Pemetrexed/Carboplatin After Osimertinib Failure in NSCLC With Brain Metastases
Status: NOT_YET_RECRUITING
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: Lazertinib|DRUG: Pemetrexed|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Efficacy of Tocilizumab in Patients With Severe COVID-19 Pneumonia
Status: COMPLETED
Conditions: COVID-19 Pneumonia
Interventions: DRUG: Tocilizumab (TCZ)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Pivotal Trial to Assess the Safety and Clinical Efficacy of the M-001 as a Standalone Universal Flu Vaccine
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: M-001|BIOLOGICAL: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Laser Therapy for Patients With Systemic Lupus Erythematosus
Status: COMPLETED
Conditions: Systemic Lupus Erythematosus|Muscle Pain|Chewing Function
Interventions: DEVICE: GaAlAs semiconductor diode laser device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT