pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Effectiveness of C-MAC Video-stylet Versus C-MAC D- Blade Video-laryngoscope for Tracheal Intubation
Status: UNKNOWN
Conditions: Difficult Mask Ventilation|Difficult Intubation
Interventions: DEVICE: C-MAC VS|DEVICE: C-MAC VL D -blade
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Effects of a Very Low Carbohydrate Diet on Symptoms of Irritable Bowel Syndrome (IBS)
Status: COMPLETED
Conditions: Diarrhea Predominant Irritable Bowel Syndrome
Interventions: OTHER: Very low carbohydrate diet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Supplementation With Aged Garlic Extract to Improve Endothelial Function in Patients With Metabolic Syndrome
Status: UNKNOWN
Conditions: Metabolic Syndrome
Interventions: DRUG: aged garlic extract|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of ZG19018 in Patients With KRAS G12C Mutant Advanced Solid Tumors.
Status: RECRUITING
Conditions: KRAS G12C Mutant Advanced Solid Tumors
Interventions: DRUG: ZG19018
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: General Anesthesia vs Paravertebral Block With General Anesthesia For Laparoscopic Sleeve Gastrectomy
Status: UNKNOWN
Conditions: Pain, Postoperative
Interventions: OTHER: general anesthesia|OTHER: Paravertebral block|OTHER: Placebo PVB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: MRI in Assessing Hypoxia in Patients With Localized Prostate Cancer Undergoing Stereotactic Body Radiation Therapy
Status: WITHDRAWN
Conditions: Prostate Cancer
Interventions: PROCEDURE: blood-oxygen-level-dependent functional magnetic resonance imaging|PROCEDURE: dynamic contrast-enhanced magnetic resonance imaging|PROCEDURE: magnetic resonance spectroscopic imaging|PROCEDURE: tissue-oxygen-level-dependent functional magnetic resonance imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effect of Orally Administrated Nitrate on Renal Parameters and Systemic Haemodynamics
Status: COMPLETED
Conditions: Hypertension
Interventions: OTHER: isotonic saline 9%|DIETARY_SUPPLEMENT: Potassium nitrate|DIETARY_SUPPLEMENT: Potassium chloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Retrieval Practice for Word Learning for Deaf and Hard of Hearing Children
Status: RECRUITING
Conditions: Hearing Loss|Language Impairment
Interventions: BEHAVIORAL: Feedback with massed trials|BEHAVIORAL: Feedback with spaced trials|BEHAVIORAL: No feedback with massed trials|BEHAVIORAL: No feedback with spaced trials|BEHAVIORAL: No teaching control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Pain Education on Chiropractic Students' Understanding of Chronic Pain
Status: RECRUITING
Conditions: Pain, Chronic|Education
Interventions: OTHER: Pain neuroscience education|OTHER: Red Flag Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A One-Year, Randomized, Double-Blind, Placebo-Controlled Trial of Rosiglitazone in Non-Alcoholic Steatohepatitis
Status: COMPLETED
Conditions: Non Alcoholic Steatohepatitis
Interventions: DRUG: rosiglitazone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Ziprasidone in the Psychosis Prodrome
Status: COMPLETED
Conditions: Psychosis Prodrome
Interventions: DRUG: ziprasidone|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fascial Defect Closure for Minimally Invasive Parastomal Hernia Repair
Status: TERMINATED
Conditions: Parastomal Hernia
Interventions: PROCEDURE: closure of parastomal hernia fascial defect
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Suprathel Versus Xeroform for the Management of Skin Graft Donor Sites
Status: TERMINATED
Conditions: Burns|Skin Graft Complications|Skin; Deformity
Interventions: OTHER: Suprathel or Xeroform donor site application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Evaluate the Safety and Efficacy of CAR-T in the Treatment of Multiple Myeloma
Status: RECRUITING
Conditions: Multiple Myeloma in Relapse
Interventions: BIOLOGICAL: BCMA/GPRC5D double CAR-T
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HeartLight Ablation in Patients With Paroxysmal Atrial Fibrillation (PAF)
Status: COMPLETED
Conditions: Paroxysmal Atrial Fibrillation
Interventions: DEVICE: EAS-AC (HeartLight)|PROCEDURE: Control Arm Ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Proximal and Distal Therapeutic Approach in Pain and Lower Limb Kinematic in People With Patellofemoral Osteoarthritis
Status: UNKNOWN
Conditions: Patellofemoral Osteoarthritis
Interventions: DEVICE: Elastic hip strap|DEVICE: Insole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Ventilation Modes Effect on Intracranial Pressure During Laparoscopic Colectomy by Optic Nerve Sheath Diameter
Status: UNKNOWN
Conditions: Laparoscopic Colectomy
Interventions: DEVICE: Volume control ventilation group|DEVICE: Pressure control ventilation-volume guaranteed group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Phase II Safety and Efficacy Study of Oral ORMD-0801 in Patients With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Type 2
Interventions: DRUG: ORMD-0801|DRUG: Placebo Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Safety, Efficacy and Systemic Exposure Study of CD5789 Cream in Adults and Adolescents With Lamellar Ichthyosis
Status: TERMINATED
Conditions: Lamellar Ichthyosis
Interventions: DRUG: CD5789 Cream 200 µg/g|DRUG: CD5789 Cream 100 µg/g|DRUG: CD5789 Cream Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: High-definition Transcranial Direct Current Stimulation and Chlorella Pyrenoidosa to Reduce Cardiovascular Risk
Status: RECRUITING
Conditions: Cardiovascular Diseases|Long Covid19
Interventions: OTHER: High Definition-transcranial Direct Current Stimulation|DIETARY_SUPPLEMENT: Chlorella Pyrenoidosa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Reducing Depressive Symptomatology With a Smartphone App
Status: COMPLETED
Conditions: Moderate Depression
Interventions: OTHER: Self-administered online CBT plus therapist check in|OTHER: Sham self-administered online CBT plus therapist check in
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant FOLFOX Plus Bevacizumab Chemotherapy in Patients With Locally Advanced Colon Cancer
Status: TERMINATED
Conditions: Colon Cancer
Interventions: DRUG: FOLFOX and bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dexmedetomidine, Ketamine and Magnesium Sulphate in Caudal Block for Hypospadias Repair
Status: RECRUITING
Conditions: Preemptive Analgesia|Dexmedetomidine|Ketamine|Magnesium Sulphate|Hypospadias|Pediatrics
Interventions: DRUG: Dexmedetomidine|DRUG: Ketamine|DRUG: Magnesium sulphate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Persona TM Tibia Clinical Outcomes Study
Status: COMPLETED
Conditions: Osteoarthritis|Rheumatoid Arthritis|Traumatic Arthritis|Polyarthritis|Collagen Disorders and/or Avascular Necrosis of the Femoral Condyle|Post-traumatic Loss of Joint Configuration|Moderate Valgus, Varus, or Flexion Deformities
Interventions: DEVICE: Persona TM Tibia
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transcranial Doppler Ultrasound Monitoring During Flow-Diverter Embolization
Status: COMPLETED
Conditions: Intracranial Aneurysm|Aneurysm, Intracranial|Giant Intracranial Aneurysm
Interventions: DEVICE: TCD Ultrasound
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Prospective Study of Fractional Flow Reserve Assessment of Intermediate Coronary Stenoses in Severe Aortic Stenosis
Status: TERMINATED
Conditions: Coronary Artery Stenoses|Aortic Stenosis
Interventions: DEVICE: Volcano iFR/FFR Verrata Plus coronary pressure/flow wire
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Formulas for Diabetes With Sucromalt & Isomaltulose on Glycemic Index, Hormones & Subjective Appetite in Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DIETARY_SUPPLEMENT: Ensure® Abbott Nutrition|DIETARY_SUPPLEMENT: Glucerna® Abbott Nutrition|DIETARY_SUPPLEMENT: Diasip® Nutricia Advanced|DIETARY_SUPPLEMENT: Glicolab®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Hyperbaric-oxygen Therapy (HBOT) Versus Placebo for Treating Vaso-Occlusive Crisis (VOC) in Sickle Cell Disease (SCD)
Status: RECRUITING
Conditions: Sickle Cell Disease|Hyperbaric Oxygen Therapy|Vaso-occlusive Crisis
Interventions: DEVICE: HBOT in Hyperbaric chamber|DEVICE: Hyperbaric chamber for placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: One Session Virtual Reality During Ongoing Treatment for Anxiety: Feasibility in Children and Adolescents
Status: NOT_YET_RECRUITING
Conditions: Anxiety Disorders|Exposure|Social Anxiety Disorder
Interventions: BEHAVIORAL: One session exposure with Virtual Reality
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Observational Study of Safety and Tolerability of Levemir™ FlexPen™ (Insulin Detemir) in the Treatment of Type 1 and Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 1|Diabetes Mellitus, Type 2
Interventions: DRUG: insulin detemir
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Optimal rhCG(Ovidrel®) Dose in Poor Responder During IVF and ICSI Cycles
Status: UNKNOWN
Conditions: in Vitro Fertilization|Poor Responder
Interventions: DRUG: recombinant hCG (Ovidrel®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Psychosocial Intervention for Bereaved Spousal Caregivers of Persons With Dementia
Status: COMPLETED
Conditions: Dementia|Bereavement
Interventions: BEHAVIORAL: the Reclaiming Yourself tool
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Role of Training and Reminder Wristwatche in Hypertension
Status: COMPLETED
Conditions: Hypertension|Adherence, Medication
Interventions: BEHAVIORAL: The Role of Training and Reminder Wristwatche in Hypertension (RoT-ReWiH)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Effect of Aerobic Exercises and Nutrition In Adolescent Girls With Anorexia
Status: UNKNOWN
Conditions: Anorexia in Adolescence
Interventions: OTHER: aerobic exercises + Diet|OTHER: diet proram
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Diet, Physical Activity and Body Composition Changes During R-CHOP
Status: WITHDRAWN
Conditions: Non-Hodgkin Lymphoma|DLBCL|Diffuse Large B Cell Lymphoma
Interventions: OTHER: 24-hour dietary recall|OTHER: Hand grip strength|OTHER: International Physical Activity Questionnaire|OTHER: Patient-reported outcomes survey|OTHER: Pittsburgh Sleep Quality Index|OTHER: Functional Assessment of Cancer Treatment - Lymphoma|OTHER: urine sample (optional)|OTHER: fecal sample (optional)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Different Dosage of Decompression Therapy on Symptoms of Lumbar Radiculopathy
Status: COMPLETED
Conditions: Lumbar Radiculopathy
Interventions: OTHER: Decompression with 30%|OTHER: Decompression with 40%|OTHER: Decompression with 50%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Role of Tofacitinib in Steroid Withdrawal in Rheumatoid Arthritis
Status: UNKNOWN
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Tofacitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Atezolizumab With Chemotherapy in Treating Patients With Anaplastic or Poorly Differentiated Thyroid Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Thyroid Gland Carcinoma|Poorly Differentiated Thyroid Gland Carcinoma|Stage IVA Thyroid Gland Anaplastic Carcinoma AJCC v8|Stage IVB Thyroid Gland Anaplastic Carcinoma AJCC v8|Stage IVC Thyroid Gland Anaplastic Carcinoma AJCC v8|Thyroid Gland Anaplastic Carcinoma|Unresectable Thyroid Gland Carcinoma
Interventions: DRUG: Atezolizumab|BIOLOGICAL: Bevacizumab|DRUG: Cobimetinib|DRUG: Nab-paclitaxel|DRUG: Paclitaxel|DRUG: Vemurafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Extracorporeal Shock Wave Combined With Autologous Platelet-rich Plasma Injection on Rotator Cuff Calcific Tendinitis
Status: NOT_YET_RECRUITING
Conditions: Rotator Cuff Tendinitis|Rotator Cuff Tendinosis
Interventions: DEVICE: Extracorporeal shock wave therapy device|BIOLOGICAL: Platelet-rich plasma
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Improving the Immune System With Human IL-7 Vaccine in Older Subjects Who Have Had Chemotherapy
Status: TERMINATED
Conditions: Breast Cancer|Colon Cancer|Bladder Cancer
Interventions: DRUG: Glycosylated Recombinant Human Interleukin-7|BIOLOGICAL: Diphtheria/Tetanus Vaccine|BIOLOGICAL: Polio Vaccine|BIOLOGICAL: Pneumococcal Vaccine|BIOLOGICAL: Hepatitis A Vaccine|BIOLOGICAL: Hepatitis B Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Thiamin Supplementation on Thiamin Status in Children With Heart Disease Receiving Diuretic Drugs
Status: UNKNOWN
Conditions: Heart Diseases
Interventions: DRUG: Thiamine Mononitrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness and Safety of the Simultaneous Radiotherapy and Hyperthermia After Transarterial Chemoembolization in Hepatocellular Carcinoma Patients Combined With Portal Vein Tumor Thrombosis
Status: COMPLETED
Conditions: Carcinoma. Hepatocellular
Interventions: RADIATION: RT and hyperthermia after TACE
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Virtual Reality Based Cue-exposure Treatment for Bulimia Nervosa
Status: COMPLETED
Conditions: Bulimia Nervosa|Binge-Eating Disorder|Binge Eating
Interventions: BEHAVIORAL: VR based cue-exposure therapy|BEHAVIORAL: Additional Cognitive-behavioral treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Use of Ulipristal Acetate in Induction of Second Trimester Missed Abortion
Status: COMPLETED
Conditions: Induction of Second Trimester Abortion
Interventions: DRUG: Ulipristal Acetate|DRUG: Misoprostol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: HER2 Imaging Study to Identify HER2 Positive Metastatic Breast Cancer Patient Unlikely to Benefit From T-DM1
Status: ACTIVE_NOT_RECRUITING
Conditions: HER-2 Positive Breast Cancer
Interventions: DRUG: T-DM1|PROCEDURE: 89Zr-trastuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Use of Steri3X for Prevention of Post-operative Wound Infections in Cesarean Sections
Status: UNKNOWN
Conditions: Surgical Site Infection|Cesarean Section; Complications, Wound, Infection (Following Delivery)|Postpartum Complication
Interventions: DEVICE: Steri3X|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: CCRT With Itraconazole in Locally Advanced Squamous Esophageal Cancer
Status: UNKNOWN
Conditions: Esophageal Neoplasm|Esophageal Diseases|Esophageal Squamous Cell Carcinoma
Interventions: DRUG: itraconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of a New Device (Buzzy®) for Procedural Pain Relief During Needle-Related Procedures in Paediatric Patients
Status: COMPLETED
Conditions: Autoimmune Rheumatologic Disease|Immune Deficiency|Pain Due to Certain Specified Procedures|Child/Adolescent Problems
Interventions: DEVICE: Buzzy|DRUG: Topical anaesthetic cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pulsed ElectroMagnetic Field (PEMF) Therapy in Treating Post-Traumatic Stress Disorder (PTSD) & Trauma
Status: COMPLETED
Conditions: Unspecified Trauma- and Stressor-Related Disorder
Interventions: DEVICE: S.C.I.O.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Long-Term Safety Study to Evaluate Methylphenidate HCL Tablets at Multiple Dose Levels in Adults With Attention Deficit Hyperactivity Disorder
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: DRUG: methylphenidate hydrochloride extended-release tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Photo-induction as a Means to Improve Cisplatin Delivery to Pleural Malignancies
Status: TERMINATED
Conditions: Pleural Effusion, Malignant
Interventions: DRUG: Cisplatin, liposomal|DRUG: Verteporfin|DEVICE: Device for Intrapleural Visudyne-mediated Low-Dose Photodynamic Therapy with integrated in situ light dosimetry
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Feasibility Study to Evaluate the Efficacy of the RenewalNail™ Plasma Treatment System in Patients With Onychomycosis (Fungal Nail)
Status: COMPLETED
Conditions: Onychomycosis of Toenail|Onychomycosis
Interventions: DEVICE: plasma treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intraoperative Subanesthetic Ketamine Versus Dexmedetomidine Infusion for Prevention of Post-traumatic Stress Disorder After Traumatic Brain Surgeries
Status: ENROLLING_BY_INVITATION
Conditions: Subanesthetic Ketamine Dexmedetomidin
Interventions: DRUG: ketamine|DRUG: dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Metastatic Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: BIOLOGICAL: filgrastim|DRUG: carmustine|DRUG: cisplatin|DRUG: melphalan|DRUG: vinorelbine tartrate|PROCEDURE: peripheral blood stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Randomized Open Label Study Evaluating the Coverage by Teleconsultation Versus Standard Follow-up of Renal Transplant Patients According to a Risk Score of Early Graft Failure (KTFS)
Status: COMPLETED
Conditions: Renal Transplant Patient
Interventions: OTHER: Teleconsultation / Standard consultation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study To Assess The Safety Of Administering CP-675,206 As A One Hour Infusion In Patients With Surgically Incurable Advanced Melanoma
Status: TERMINATED
Conditions: Melanoma
Interventions: DRUG: CP-675,206
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 1% vs. 2 % Lignocaine for Endobronchial Ultrasound Guided Transbronchial Needle Aspiration
Status: COMPLETED
Conditions: Bronchopulmonary Diseases
Interventions: DRUG: Lignocaine 1% concentration solution|DRUG: Lignocaine 2% concentration solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Epoetin Alfa in Treating Anemia in Patients Who Are Receiving Chemotherapy
Status: COMPLETED
Conditions: Anemia|Breast Cancer|Chronic Myeloproliferative Disorders|Drug/Agent Toxicity by Tissue/Organ|Leukemia|Lung Cancer|Lymphoma|Multiple Myeloma and Plasma Cell Neoplasm|Precancerous Condition|Small Intestine Cancer|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: BIOLOGICAL: epoetin alfa|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Raltegravir And Darunavir Antiretroviral in Antiretroviral Naive Patients
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Raltegravir|DRUG: Darunavir|DRUG: Ritonavir|DRUG: Tenofovir/Emtricitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Antimalarial Drugs Regimens in Patient With Plasmodium Vivax Malaria in Thailand
Status: UNKNOWN
Conditions: Acute Uncomplicated Malaria With P.Vivax Infection
Interventions: DRUG: Artesunate|DRUG: Chloroquine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cost-Effectiveness Study in the Reduction of Coronary Restenosis With Sirolimus-Eluting Stents
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DEVICE: bare metal stent|DEVICE: Cypher-Stent (Implantation of a sirolimus-eluting stent)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: |Masking: |Primary Purpose:
Clinical trial: Simvastatin and Emotional Processing (OxSTEP)
Status: COMPLETED
Conditions: Depression|Inflammation
Interventions: DRUG: Simvastatin 20mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of DNL151 in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: DNL151|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pivot-Flex Foot: Optimal Coupling Ratio Between Transverse and Sagittal-plane Motions Using a Torsionally Adaptive Prosthesis for Individuals With Lower Limb Amputation
Status: RECRUITING
Conditions: Lower Extremity Amputation
Interventions: DEVICE: Torsionally adaptive prosthesis with 0:1 coupling ratio|DEVICE: Torsionally adaptive prosthesis with 1:6 coupling ratio|DEVICE: Torsionally adaptive prosthesis with 1:4 coupling ratio|DEVICE: Torsionally adaptive prosthesis with 1:3 coupling ratio|DEVICE: Torsionally adaptive prosthesis with 1:2 coupling ratio
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Probiotic Supplements on Osteoarthritis Outcomes
Status: RECRUITING
Conditions: Knee Osteoarthritis
Interventions: DIETARY_SUPPLEMENT: Probiotic supplements|DIETARY_SUPPLEMENT: Placebo supplements
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A RCT of TNF and ENT in the Treatment of Long-term Prognosis With Hepatitis B-related HCC After Curative Resection
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma Recurrent
Interventions: DRUG: Tenofovir disoproxil fumarate 300mg|DRUG: Entecavir 0.5 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prevention of Post Traumatic Stress Disorder by Early Treatment
Status: COMPLETED
Conditions: Post-traumatic Stress Disorder
Interventions: PROCEDURE: Cognitive Behavioral Therapy|PROCEDURE: Cognitive Therapy|DRUG: Escitalopram|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Implementation of a Respiratory Physiotherapy Program in Post COVID-19 Patients Through Tele-assistance
Status: UNKNOWN
Conditions: Covid19- Coronavirus- Sars-cov-2
Interventions: OTHER: Chest physiotherapy post-covid19
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of PDE4 Inhibition With Roflumilast for the Management of Atopic Dermatitis (INTEGUMENT-II)
Status: COMPLETED
Conditions: Atopic Dermatitis Eczema
Interventions: DRUG: Roflumilast (ARQ-151) cream|DRUG: Vehicle cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Learn About the Study Medicine (Called PF-07220060 in Combination With PF-07104091) In Participants With Breast Cancer and Solid Tumors
Status: RECRUITING
Conditions: Breast Cancer|Solid Tumors
Interventions: DRUG: PF-07220060 + PF-07104091 combination dose escalation|DRUG: PF-07220060 + PF-07104091 combination dose escalation|DRUG: PF-07220060 + PF-07104091 combination dose escalation|DRUG: PF-07220060 + PF-07104091 combination dose escalation|DRUG: PF-07220060 + PF-07104091 combination dose escalation|DRUG: PF-07104091 + PF-07220060 + fulvestrant dose expansion|DRUG: PF-07104091 + PF-07220060 + fulvestrant dose expansion|DRUG: PF-07104091 + PF-07220060 + letrozole dose expansion|DRUG: PF-07220060 + PF-07104091 combination dose escalation|DRUG: PF-07220060 + PF-07104091 combination dose escalation|DRUG: PF-07220060 + PF-07104091 combination dose escalation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vitamin K to Attenuate Coronary Artery Calcification in Hemodialysis Patients
Status: COMPLETED
Conditions: End-stage Kidney Disease
Interventions: DRUG: Vitamin K1|DRUG: Microcrystalline Methylcellulose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Trial of E-Health Platform Supported Care vs Usual Care After Exacerbation of COPD
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Diseases
Interventions: BEHAVIORAL: myCOPD|BEHAVIORAL: Written Self management plan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Single-arm, Multi-center Clinical Study of Pyrotinib Maleate Tablets Combined With Albumin-bound Paclitaxel and Trastuzumab in Neoadjuvant Treatment of Her2-positive Early or Locally Advanced Breast Cancer
Status: RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Pyrotinib combined with albumin-bound paclitaxel and trastuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess Stroke Risk Among Users of Typical Versus Atypical Antipsychotics Stratified by Broad Age Group
Status: COMPLETED
Conditions: Stroke
Interventions: DRUG: Haloperidol|DRUG: Typical Antipsychotics|DRUG: Atypical Antipsychotics
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Judo Training Compared to Ball Games on Motor Skills, Physical Fitness, Quality of Life and Cardiovascular Parameters in Children and Adolescents
Status: RECRUITING
Conditions: Child Behavior|Adolescent Behavior
Interventions: BEHAVIORAL: Judo Training|BEHAVIORAL: Ball Games
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Brain Connectivity as a Biomarker of Response to Transcranial Stimulation by Continuous Current in Patients With Stroke
Status: UNKNOWN
Conditions: Stroke
Interventions: DEVICE: Direct Current Transcranial Stimulation - tDCS|DEVICE: Sham Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Safety and Efficacy of Synvisc in Patients With Symptomatic Shoulder Osteoarthritis
Status: COMPLETED
Conditions: Osteoarthritis|Musculoskeletal Diseases
Interventions: DEVICE: Synvisc (hylan G-F 20)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of PG2 to Treat Idiopathic Thrombocytopenic Purpura (ITP) Patients
Status: COMPLETED
Conditions: Idiopathic Thrombocytopenic Purpura (ITP)
Interventions: DRUG: PG2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intervention for Caregivers of Patients Who Have Recently Undergone HSCT
Status: WITHDRAWN
Conditions: Caregiver Anxiety|Caregiver Distress|Caregiver Health Related QOL
Interventions: BEHAVIORAL: Psycho-educational intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Youth FORWARD Phase 2 YRI and EPP Study
Status: COMPLETED
Conditions: Mental Health Impairment|Mental Health Disorder|Psychosocial Problem
Interventions: BEHAVIORAL: Youth Readiness Intervention (YRI)|BEHAVIORAL: Entrepreneurship Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Interventional Study to Assess the Efficacy and Safety of Buprenorphine in Korean Patients With Spinal Disorders
Status: COMPLETED
Conditions: Spinal Disorder
Interventions: DRUG: Buprenorphine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Norepinephrine or Phenylephrine in Bolus for Hypotension in Cesarean Delivery
Status: COMPLETED
Conditions: Hypotension|Spinal Anesthesia
Interventions: DRUG: Phenylephrine 100 mcg|DRUG: Norepinephrine 5 mcg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clopidogrel Pharmacogenetics (PGX) Bench to Bedside
Status: COMPLETED
Conditions: Metabolism of Clopidogrel
Interventions: DRUG: Clopidogrel|DRUG: Omeprazole/Clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: OrACELL™ vs. Connective Tissue in Miller Class 3 Defects
Status: COMPLETED
Conditions: Gingival Recession
Interventions: DEVICE: OrACELL|DEVICE: Connective Tissue Graft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: WALANT Technique (Wide Awake Local Anesthesia No Tourniquet) for Carpal Tunnel Release.
Status: COMPLETED
Conditions: Carpal Tunnel Release
Interventions: PROCEDURE: TRONC|PROCEDURE: WALANT|PROCEDURE: Tourniquet|DRUG: Ropivacaine|DRUG: Lidocaine + Epinephrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Volumetric Analysis of Bone Following Jaw Cysts Enucleation With and Without Alb-PRF
Status: RECRUITING
Conditions: Jaw Cysts
Interventions: OTHER: Enucleation with albumin PRF|OTHER: Enucleation without albumin PRF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TQB2450 Plus Anlotinib Combined With Chemotherapy in the Treatment of Gastric or Gastroesophageal Junction Adenocarcinoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Gastric Cancer|Adenocarcinoma of Esophagogastric Junction
Interventions: DRUG: TQB2450/Anlotinib hydrochloride/Oxaliplatin/Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Intervention to Improve Motor Skills in Young Children
Status: COMPLETED
Conditions: Physical Activity|Fundamental Motor Skills|Development, Child|Self-regulation
Interventions: BEHAVIORAL: Fundamental Motor Skills App|BEHAVIORAL: Unstructured Physical Activity App
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effects of One-Time Pregnenolone, Dehydroepiandrosterone (DHEA), or Placebo Administration On Withdrawal Symptoms, Mood, Craving And Cigarette Evaluation Ratings In Male Smokers
Status: COMPLETED
Conditions: Substance Withdrawal Syndrome
Interventions: DIETARY_SUPPLEMENT: dehydroepiandrosterone (DHEA)|DIETARY_SUPPLEMENT: pregnenolone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 1a/b Study on Safety of IMX101 in H. Pylori-negative and H. Pylori-infected Healthy Volunteers
Status: COMPLETED
Conditions: Helicobacter Pylori Infected Subjects|Helicobacter Pylori Naive Subjects
Interventions: BIOLOGICAL: CTA control|BIOLOGICAL: IMX101 vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Pharmacokinetics, Pharmacodynamics, and Clinical Activity Study in VLBW Neonates of BSYX-A110
Status: COMPLETED
Conditions: Staphylococcal Sepsis
Interventions: DRUG: Pagibaximab (formerly BSYX-A110)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: ATG-GCSF in New Onset Type 1 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: DRUG: Anti-Thymocyte Globulin (ATG)|DRUG: Granulocyte colony stimulating factor (GCSF)|DRUG: Placebo (for ATG)|DRUG: Placebo (for GCSF)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of the Treatment of Acute Sinusitis With Standard-dose Versus High-dose Amoxicillin/Clavulanate
Status: COMPLETED
Conditions: Sinusitis
Interventions: DRUG: standard dose amoxicillin/clavulanate|DRUG: high dose amoxicillin/clavulanate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of BMS-824393 in Combination With Peginterferon Alfa-2a (Pegasys) and Ribavirin (Copegus) in Treatment Naive Subjects With Chronic Hepatitis C Virus Genotype I
Status: WITHDRAWN
Conditions: Chronic Hepatitis C Virus Genotype 1
Interventions: DRUG: BMS-824393|DRUG: BMS-824393|DRUG: BMS-824393|DRUG: Placebo|DRUG: Peginterferon Alpha-2a|DRUG: Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: UNIPDES- An Internet-Based Transdiagnostic Intervention for College Students' Psychological Symptoms
Status: NOT_YET_RECRUITING
Conditions: Mental Health Issue
Interventions: OTHER: UNIPDES - Internet Based Intervention - GUIDED|OTHER: UNIPDES - Internet Based Intervention - UNGUIDED
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety of Ibuprofen After Major Orthopaedic Surgeries
Status: RECRUITING
Conditions: Pain, Acute|Hip Arthropathy|Knee Arthropathy|Safety Issues|Analgesia|Analgesic Adverse Reaction|Postoperative Pain|Postoperative Complications
Interventions: DRUG: Ibuprofen|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Pharmacology of a Dual Pharmacophore in Healthy Volunteers
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: GSK961081|DRUG: GSK961081 matching placebo|DRUG: Propranolol|DRUG: Propranolol matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: |Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Modified Functional Appliance With Expander
Status: ACTIVE_NOT_RECRUITING
Conditions: Class II Malocclusion
Interventions: DEVICE: Modified twin block appliance with expander|DEVICE: Conventional twin block appliance with expander
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Comparing Bupivacaine, Lidocaine, and a Combination of Bupivacaine and Lidocaine for Labor Epidural Activation
Status: COMPLETED
Conditions: Labor Pain
Interventions: DRUG: 1% Lidocaine|DRUG: 0.25% Bupivacaine|DRUG: Bupivacaine plus Lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Antialbuminuric Effects of Valsartan and Lisinopril
Status: TERMINATED
Conditions: Hypertension|Early Diabetic Nephropathy
Interventions: DRUG: VALSARTAN, VALSARTAN PLUS HCTZ, LISINOPRIL, LISINOPRIL PLUS HCTZ
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A First-in-Human SAD/MAD Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of ENC1018 in Healthy Adult Subjects
Status: NOT_YET_RECRUITING
Conditions: Healthy
Interventions: DRUG: ENC1018 for SAD|DRUG: Placebo for SAD|DRUG: ENC1018 for MAD|DRUG: Placebo for MAD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Impact of a Digital Home-based Falls Prevention Program on Elderly People
Status: NOT_YET_RECRUITING
Conditions: Fall
Interventions: DEVICE: Biofeedback device|BEHAVIORAL: Education on falls risk|OTHER: Medication review|DIAGNOSTIC_TEST: Visual and auditory screening
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Caffeine, Postoperative Delirium, and Change in Outcomes After Surgery (CAPACHINOS-2) Study
Status: RECRUITING
Conditions: Postoperative Delirium|Postoperative Cognitive Dysfunction|Mild Cognitive Impairment
Interventions: DRUG: Dextrose Water|DRUG: Caffeine citrate|DRUG: Caffeine citrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Safety, Tolerability and PK of NPT520-34 in Healthy Subjects
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: NPT520-34 (125 mg)|DRUG: Placebos (125 mg)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Two Different Dosages of Nebulized Steroid Versus Parenteral Steroid in the Management of COPD Exacerbations
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Budesonide 4 mg|DRUG: Budesonide 8 mg|DRUG: Metil prednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Tetracaine Versus Lidocaine Gel for Anesthetic Effect and Comfort in Patients Undergoing LASIK
Status: TERMINATED
Conditions: Pain
Interventions: DRUG: Tetracaine drop|DRUG: Lidocaine gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Cervical Changes by 4h of Hyper-buoyancy Flotation and Followed by 15 Mins 1g Re-loading
Status: COMPLETED
Conditions: Intervertebral Disc Herniation|Stiffness; Spine
Interventions: DEVICE: Hyperbuoyancy Floatation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Intensive Ambulance-delivered Blood Pressure Reduction in Hyper-Acute Stroke Trial
Status: COMPLETED
Conditions: Stroke, Acute|Cerebrovascular Disorders
Interventions: DRUG: urapidil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Pain on Propofol Injection.
Status: COMPLETED
Conditions: Injection Site Irritation
Interventions: DRUG: Propofol lidocaine through large vein|DRUG: Propofol lidocaine through small vein
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Multiple Ascending Dose Study of CAT-1004 in Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: CAT 1004|DRUG: Placebo|DRUG: CAT 1004|DRUG: CAT 1004|DRUG: CAT 1004|DRUG: CAT 1004
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: mHealth for Breast Cancer Survivors With Insomnia
Status: RECRUITING
Conditions: Breast Cancer Survivor|Insomnia
Interventions: BEHAVIORAL: Faster Asleep Smart Speaker Program|BEHAVIORAL: Faster Asleep Website
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Does Caffeine Enhance Bowel Recovery After Colorectal Surgery?
Status: COMPLETED
Conditions: Postoperative Ileus
Interventions: DRUG: Caffeine Citrate|OTHER: Water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MRI Derived Organ & Tissue Mass Changes With Weight Loss - Ancillary to Look AHEAD
Status: COMPLETED
Conditions: Cardiovascular Diseases|Atherosclerosis|Obesity|Diabetes Mellitus, Non-insulin Dependent|Heart Diseases|Myocardial Infarction|Diabetes Mellitus
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p