pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Study of Troxatyl™ Administered by Continuous Infusion to Subjects With Refractory Acute Myelogenous Leukemia (AML)
Status: TERMINATED
Conditions: Acute Myelogenous Leukemia
Interventions: DRUG: Troxatyl™ (Cytotoxic Chemotherapeutic)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Observance and the Tolerance of a Motor Training Program
Status: TERMINATED
Conditions: Hemiplegia|Stroke
Interventions: DEVICE: Active tDCS|DEVICE: Sham tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of New Specifications (2.25mm) of FirehawkTM in the Treatment of Coronary Heart Disease ( Firehawk_2.25 )
Status: COMPLETED
Conditions: Coronary Heart Disease
Interventions: DEVICE: FirehawkTM 2.25mm
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immune Modulatory DC Vaccine Against Brain Tumor
Status: UNKNOWN
Conditions: Diffuse Intrinsic Pontine Glioma or Glioblastoma
Interventions: BIOLOGICAL: Immunomodulatory DC vaccine to target DIPG and GBM
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non-invasive Tumor Immunoglobulin Gene Next Generation Sequencing (IgNGS) in Diffuse Large B Cell Lymphoma (DLBCL)
Status: UNKNOWN
Conditions: Lymphoma, Large B-Cell, Diffuse
Interventions: DIAGNOSTIC_TEST: IgNGS from circulating tumor DNA
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Budesonide for Mycophenolic Acid-induced Diarrhea in Renal Transplant Recipients
Status: TERMINATED
Conditions: Diarrhea
Interventions: DRUG: Entocort|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Obinutuzumab (RO5072759) Plus Chemotherapy in Comparison With Rituximab Plus Chemotherapy Followed by Obinutuzumab or Rituximab Maintenance in Patients With Untreated Advanced Indolent Non-Hodgkin's Lymphoma (GALLIUM)
Status: COMPLETED
Conditions: Non-Hodgkin's Lymphoma
Interventions: DRUG: Obinutuzumab|DRUG: Cyclophosphamide|DRUG: Doxorubicin|DRUG: Vincristine|DRUG: Prednisone|DRUG: Bendamustine|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High Flow Nasal Cannula Oxygen During Sedation for Video-assisted Thoracoscopic Surgery
Status: UNKNOWN
Conditions: Chronic Obstructive Pulmonary Disease|Respiratory Failure
Interventions: COMBINATION_PRODUCT: High flow nasal cannula|COMBINATION_PRODUCT: CONTROL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: An Efficacy and Safety Study of Fremanezumab in Adults With Migraine
Status: COMPLETED
Conditions: Migraine Prophylaxis
Interventions: DRUG: Fremanezumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cervical Traction, Passive Accessory Intervertebral Movements and Active Strength Training in Cervical Radiculopathy
Status: COMPLETED
Conditions: Cervical Radiculopathy
Interventions: OTHER: Manual Cervical Traction|OTHER: Passive Accessory Intervertebral Movements|OTHER: Active Strength Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: BEADI - The Bliss Cluster Randomised Control Trial on the Effects of Active Dissemination of Information (BEADI)
Status: UNKNOWN
Conditions: Premature Babies
Interventions: BEHAVIORAL: Effects of Active Dissemination
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Autologous Bone Marrow Transplanted Via Transendocardial Catheter to Chronic Myocardial Infarct Border Zone
Status: COMPLETED
Conditions: Ventricular Dysfunction|Myocardial Infarction
Interventions: PROCEDURE: Transendocaridal Transplantation of Autologous Bone Marrow
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Klotho in Chronic Kidney Disease-associated Pruritis (CKD-aP)
Status: UNKNOWN
Conditions: Chronic Kidney Disease-associated Pruritus
Interventions: OTHER: skin biopsy|RADIATION: narrowband ultraviolet B
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Phase 1 Study of Anti-OX40 in Patients With Advanced Cancer
Status: COMPLETED
Conditions: Advanced Cancer
Interventions: DRUG: Cohort 1 anti-OX40|DRUG: Cohort 2 anti-OX40|DRUG: Cohort 3 anti-OX40|BIOLOGICAL: Tetanus Day 29|BIOLOGICAL: Tetanus Day 1|BIOLOGICAL: KLH Day 1|BIOLOGICAL: KLH Day 29
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: IL-10, IL-12 and IL-18 Levels in the Gingival Crevicular Fluid of Patients With Periodontitis and Healthy Controls
Status: COMPLETED
Conditions: Periodontitis
Interventions: OTHER: No intervention was applied to the groups the samples will be collected in terms of the diagnosis ( periodontitis, healthy)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Antibiotic Treatment Duration (7 vs 14 Days) Comparison in Blood Stream Infection Causes by Enterobacteriaceae
Status: COMPLETED
Conditions: Enterobacteriaceae Infections|Bloodstream Infection
Interventions: OTHER: 7 days course of antibiotic treatment|OTHER: 14 days course of antibiotic treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy In Treating Patients With Metastatic or Unresectable Solid Tumors
Status: COMPLETED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: fluorouracil|DRUG: irinotecan hydrochloride|DRUG: leucovorin calcium|DRUG: oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Examination of The Effects of Telerehabilitation in Painful Healthcare Workers With and Without COVID-19 Infection
Status: COMPLETED
Conditions: COVID-19 Respiratory Infection
Interventions: OTHER: Progressive Myofascial Relaxation Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects Diflunisal on the Levels of BMS-986165 in Healthy Participants
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DRUG: BMS-986165|DRUG: diflunisal
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Dexmetomidine With Erector Spinae Plane Block in Cholecystectomy
Status: COMPLETED
Conditions: Dexmedtomidine in Erector Spinae Block for Laparscopic Cholecystectomy
Interventions: DRUG: dexmedetomidine as adjuvant with bupivacaine|DRUG: Bupivacain only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Combination Chemotherapy, Radiation Therapy, and an Autologous Peripheral Blood Stem Cell Transplant in Treating Young Patients With Atypical Teratoid/Rhabdoid Tumor of the Central Nervous System
Status: COMPLETED
Conditions: Childhood Atypical Teratoid/Rhabdoid Tumor
Interventions: RADIATION: 3-Dimensional Conformal Radiation Therapy|PROCEDURE: Autologous Hematopoietic Stem Cell Transplantation|DRUG: Carboplatin|DRUG: Cisplatin|DRUG: Cyclophosphamide|DRUG: Etoposide|BIOLOGICAL: Filgrastim|OTHER: Laboratory Biomarker Analysis|DRUG: Leucovorin Calcium|DRUG: Methotrexate|DRUG: Thiotepa|DRUG: Vincristine Sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Topiramate Treatment of Hazardous and Harmful Alcohol Use in Veterans With TBI
Status: COMPLETED
Conditions: Traumatic Brain Injury (TBI)|Hazardous and Harmful Alcohol Use
Interventions: BEHAVIORAL: Medical Management Counseling|DRUG: Topiramate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Improved Outcome in Allogeneic Hematopoietic Stem Cell Transplant (HSCT) Patients by Reducing Caregiver Distress
Status: COMPLETED
Conditions: Hematopoietic/Lymphoid Cancer
Interventions: BEHAVIORAL: fPER
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Tegoprazan Versus Esomeprazole-containing Bismuth Quadruple Therapy for Eradication of Helicobacter Pylori
Status: COMPLETED
Conditions: Helicobacter Pylori Infection
Interventions: DRUG: Tegoprazan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Venlafaxine for Postoperative Pain of Laparoscopic Cholecystectomy
Status: NOT_YET_RECRUITING
Conditions: Laparoscopic Cholecystectomy
Interventions: DRUG: Venlafaxine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, Pharmacokinetics (PK) and Pharmacodynamics (PD) of a Single Ascending Dose (SAD) of CAN106 Administered Intravenously (IV) in Healthy Subjects
Status: COMPLETED
Conditions: PNH
Interventions: DRUG: CAN106|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Brain Oxygen Tension Level and Cleaved-tau Protein to Detect Vasospasm After SAH
Status: TERMINATED
Conditions: Subarachnoid Hemorrhage|Cerebral Vasospasm
Interventions: DEVICE: Licox Brain Oxygen Monitor|OTHER: CSF|OTHER: Whole blood
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of Pevonedistat in Adult East Asian Participants
Status: COMPLETED
Conditions: Leukemia, Myeloid, Acute|Myelodysplastic Syndromes
Interventions: DRUG: Pevonedistat 25 mg/m^2|DRUG: Pevonedistat 44 mg/m^2|DRUG: Pevonedistat 10 mg/m^2|DRUG: Pevonedistat 20 mg/m^2|DRUG: Azacitidine 75 mg/m^2
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Vasopressors on Immune Response
Status: COMPLETED
Conditions: Endotoxemia
Interventions: DRUG: Norepinephrine|DRUG: Phenylephrine|DRUG: Vasopressins|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Mindfulness for Mothers of Children With Disabilities
Status: COMPLETED
Conditions: Parental Burnout|Caregiver Burnout
Interventions: BEHAVIORAL: Mindfulness and Compassionate Living Course (MCLC)|BEHAVIORAL: Usual care intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Medico-economics and QoL of Obese Patients Followed by Medical Analysis Laboratories (BIOSAOS )
Status: WITHDRAWN
Conditions: Obesity Hypoventilation Syndrome|Obstructive Sleep Apnea
Interventions: OTHER: Care pathway
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Dose Escalation/ Expansion Study of CA-4948 as Monotherapy in Patients With Acute Myelogenous Leukemia (AML) or Myelodysplastic Syndrome (MDS)
Status: RECRUITING
Conditions: Acute Myelogenous Leukemia|Myelodysplastic Syndrome
Interventions: DRUG: Emavusertib|DRUG: Venetoclax|DRUG: Emavusertib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acute Effect of Inferential Therapy (IFT) and Short Wave Diathermy (SWD) on Balance in Subjects With Knee Pain
Status: UNKNOWN
Conditions: Knee Acute and Chronic Pain
Interventions: DEVICE: Inferential therapy|DEVICE: short wave diathermy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Dose-dense Chemotherapy for HR+/HER2- Breast Cancer Patients With High Proliferation Index
Status: RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: dose-dense nab-paclitaxel followed by EC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Potential Risk Factors for Stroke
Status: COMPLETED
Conditions: Carotid Atherosclerosis|Cerebrovascular Accident|Diabetes Mellitus|Hypercholesterolemia|Hypertension
Interventions: PROCEDURE: cytokine and leukocyte activation profile
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Light Sedation or Intubated General Anesthesia in Patients With Brain Cancer Undergoing Craniotomy
Status: COMPLETED
Conditions: Adult Brain Tumor
Interventions: PROCEDURE: Arm I (light sedation)|PROCEDURE: Arm II (intubated general anesthesia)|PROCEDURE: Arm II (intubated general anesthesia)|OTHER: Arm II (intubated general anesthesia)|PROCEDURE: Arm I (light sedation)|OTHER: Arm I (light sedation)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Evaluate the Effect of LY2189265 on the Speed at Which Food and Drink Leaves the Stomach in Patients With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: BIOLOGICAL: LY2189265|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Biocollection of Rare Pediatric-onset of Autoimmune and Autoinflammatory Diseases
Status: NOT_YET_RECRUITING
Conditions: Systemic Lupus|Autoimmune Diseases|Autoinflammatory Disease|Genetic Disease
Interventions: GENETIC: Blood sample for genetic analysis|OTHER: Blood sample for immunological response assessments|OTHER: Blood sample to identify relevant biomarker of the disease
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study of Aflibercept in Combination With FOLFIRI in Patients With Second-Line Metastatic Colorectal Cancer in Japan
Status: COMPLETED
Conditions: Colorectal Cancer Metastatic
Interventions: DRUG: Aflibercept|DRUG: Levofolinate|DRUG: Irinotecan|DRUG: 5-FU
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Measurement of Cerebral and Peripheric Tissue Oxygenation in Anemic Preterm Infants Who Underwent Blood Transfusion
Status: UNKNOWN
Conditions: Anemic Preterms, Cerebral Oxygenation,Somatic Oxygenation,Blood Transfusion
Interventions: DEVICE: near infrared spectroscopy: invos 5100|DEVICE: INVOS 5100|DEVICE: near infrared spectroscopy device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Treatment of Sleep Apnea With Oral Appliances
Status: UNKNOWN
Conditions: Obstructive Sleep Apnea
Interventions: DEVICE: monobloc oral appliance|DEVICE: twinblock oral appliance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Slow Release Hydrocortisone on Fed & Fasting Volunteers; Immediate Release on Fasting Only
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Dexamethasone|DRUG: Chronocort: fasted|DRUG: Immediate release hydrocortisone: fasted|DRUG: Chronocort: fed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety/Efficacy Study of Levodopa-Carbidopa Intestinal Gel in Parkinson's Subjects
Status: COMPLETED
Conditions: Dyskinesias|Parkinson's Disease|Severe Motor Fluctuations
Interventions: DRUG: Levodopa-carbidopa intestinal gel|DEVICE: CADD-Legacy® 1400 ambulatory infusion pump|DEVICE: PEG tube|DEVICE: J-tube
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Determining Lipid Content in Stool After Alpha-cyclodextrin
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DIETARY_SUPPLEMENT: Alpha-cyclodextrin|DIETARY_SUPPLEMENT: Placebo|RADIATION: Triolein radiolabeled with 100 microcuries of 3^Hydrogen|RADIATION: Tripalmitin radiolabeled with 20 microcuries of 14^Carbon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Conventional Versus Hypofractionated Radiation in High Risk Prostate Patients
Status: UNKNOWN
Conditions: High-risk Prostate Cancer
Interventions: RADIATION: Standard Radiation Treatment|RADIATION: Hypofractionated radiation treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The PartoMa Project: Enabling Best Post Possible Childbirth Care in Tanzania.
Status: UNKNOWN
Conditions: Stillbirth|Delivery Complication|Delivery Delayed|Apgar; 4-7 at 1 Minute|Apgar; 0-3 at 1 Minute|Cesarean Section Complications
Interventions: BEHAVIORAL: The PartoMa guidelines and training
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Comparison of Biphasic Insulin Aspart Produced by the NN2000 Process to Current Process to in Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: biphasic insulin aspart
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Total Energy Expenditure, Protein Kinetics, and Body Composition in Recovering Burn Children.
Status: COMPLETED
Conditions: Energy Expenditure in Burn Children|Protein Turnover in Burn Children
Interventions: OTHER: Use of Stable Isotope to Measure Energy Expenditure and Protein Turnover
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Healthy heaAring for Healthy Ageing: Data-driven Hearing Rehabilitation Intervention to Promote Healthy Hearing
Status: NOT_YET_RECRUITING
Conditions: Sensorineural Hearing Loss|Cognitive Decline
Interventions: OTHER: Individualised data-driven hearing rehabilitation|OTHER: Standard care hearing rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Pre-emptive Transcutaneous Neuro-muscular Electrical Stimulation for Dysphagia in Long Term Intubated Patients
Status: WITHDRAWN
Conditions: Deglutition Disorder
Interventions: PROCEDURE: Transcutaneous neuro-muscular electrical stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluate Safety, Tolerability and Pharmacokinetics of Fadanafil （XZP-5849）in Chinese Healthy Adult Male Subjects
Status: COMPLETED
Conditions: Healthy Subject
Interventions: DRUG: Fadanafil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Role of Barrier Resection in Local Control for Extremity Recurrent Soft Tissue Sarcomas
Status: UNKNOWN
Conditions: Local Recurrence of Malignant Tumor of Soft Tissue
Interventions: PROCEDURE: barrier resection/1cm resection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Morphine-Sparing Efficacy Of Parecoxib In Pain Treatment After Radical Prostatectomy
Status: TERMINATED
Conditions: Pain, Postoperative
Interventions: DRUG: Morphine, Parecoxib|DRUG: Morphine, Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Raltegravir Activity In Lymphoid Tissues
Status: WITHDRAWN
Conditions: HIV Infection|HIV Infections
Interventions: DRUG: Efavirenz + Tenofovir DF/Emtricitabine|DRUG: Raltegravir + Tenofovir DF/Emtricitabine|PROCEDURE: Colonoscopy with biopsies|PROCEDURE: Inguinal Lymph Node Excision
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety and Efficacy of SEBORRHEAMEDIS Face Cream in Patients With Seborrheic Dermatitis
Status: COMPLETED
Conditions: Seborrheic Dermatitis
Interventions: DEVICE: SEBORRHEAMEDIS Face Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Peer Support Model for Depression Care in Patients With Diabetes Mellitus
Status: UNKNOWN
Conditions: Diabetes Mellitus|Depression
Interventions: BEHAVIORAL: Peer support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Metabolic Heterogeneity Underlying Hypertriglyceridemia: Hepatic Triglyceride Biosynthesis in Humans With Different Insulin Resistance Phenotypes
Status: RECRUITING
Conditions: Insulin Resistance|Hypertriglyceridemia
Interventions: BEHAVIORAL: Standardized Dinner|BEHAVIORAL: Premeal exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Cytomegalovirus (CMV) Specific Cytotoxic T Lymphocytes (CTL) When Used for Prophylaxis Against CMV in Recipients of Allogeneic, T Cell Depleted Stem Cell Transplants
Status: COMPLETED
Conditions: Cytomegalovirus Infections
Interventions: BIOLOGICAL: CMV Specific Cytotoxic T Lymphocytes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Modified Placement of Two Additional Pedicle Screws at the Fracture Level for the Treatment of Thoracolumbar Burst Fractures--a Study Protocol of a Randomised Controlled Trial
Status: UNKNOWN
Conditions: Posterior Short-segment Pedicle Instrumentation
Interventions: DEVICE: fractured level screws-distraction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Upifitamab Rilsodotin in Combination With Carboplatin in Participants With High-grade Serous Ovarian Cancer
Status: TERMINATED
Conditions: Platinum-sensitive Ovarian Cancer (UPGRADE-A)
Interventions: DRUG: XMT-1536 (Upifitamab Rilsodotin)|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A First-in-Human, Double Blind, Single Dose Study in Healthy Subjects and Subjects With Mild Atopic Asthma.
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: AMG 282|DRUG: AMG 282 Matching Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Postnatal Smoking Relapse, Its Associated Risk Factors, and a Proactive Sustainable Preventive Intervention
Status: COMPLETED
Conditions: Cigarette Smoking
Interventions: BEHAVIORAL: Smoking abstinence counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Cross-Over, Multi-Center Trial to Evaluate the Diagnostic Efficacy and Safety of [123I]NAV5001 as an Imaging Agent to Aid in the Diagnosis of Parkinsonian Syndromes
Status: WITHDRAWN
Conditions: Parkinson's Syndrome
Interventions: DRUG: NAV5001|DRUG: DaTscan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: RegoNivo vs Standard of Care Chemotherapy in AGOC
Status: ACTIVE_NOT_RECRUITING
Conditions: Gastro-Oesophageal Cancer
Interventions: DRUG: Regorafenib|BIOLOGICAL: Nivolumab|DRUG: Docetaxel|DRUG: Paclitaxel|DRUG: Irinotecan|DRUG: Trifluridine/Tipracil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of Radial ESWT on Upper Trapezius Mtrps
Status: COMPLETED
Conditions: Myofascial Pain Syndrome|Myofascial Trigger Point Pain|Upper Trapezius Trigger Points
Interventions: DEVICE: Extracorporeal Shockwave Therapy|DEVICE: Extracorporeal Shockwave Therapy|DEVICE: Ultrasound therapy, Massage, Heat pack
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Radium-223 in Combination With Tasquinimod in Bone-only Metastatic Castration-Resistant Prostate Cancer
Status: WITHDRAWN
Conditions: Prostate Cancer|Bone-only Metastatic Castration-Resistant Prostate Cancer (CRPC)
Interventions: DRUG: Tasquinimod|RADIATION: Radium 223
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of the DANUBIO Paclitaxel Eluting Balloon in In-Stent Restenosis Lesions (DEBREST)
Status: COMPLETED
Conditions: In-stent Coronary Artery Restenosis
Interventions: DEVICE: Danubio paclitaxel-eluting balloon
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mind-body Interventions in Cardiac Patients
Status: COMPLETED
Conditions: Acute Coronary Syndrome|Congestive Heart Failure
Interventions: OTHER: Positive Psychology|BEHAVIORAL: Relaxation Response|BEHAVIORAL: Recollection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Safety and Tolerability of Aducanumab in Participants With Alzheimer's Disease Who Had Previously Participated in the Aducanumab Studies 221AD103, 221AD301, 221AD302 and 221AD205
Status: TERMINATED
Conditions: Alzheimer's Disease
Interventions: DRUG: Aducanumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Anlotinib Hydrochloride Capsule Combined With Chemotherapy as First-line Treatment in Subjects With RAS/BRAF Wild Metastatic Colorectal Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: Anlotinib hydrochloride capsule|DRUG: Bevacizumab|DRUG: Oxaliplatin|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Experimental Medication BMS-986263 in Adults With Advanced Hepatic Fibrosis After Cure of Hepatitis C
Status: COMPLETED
Conditions: Hepatic Cirrhosis|Liver Fibrosis
Interventions: DRUG: BMS-986263|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Innovative Tool to Analyse Synovial Fluid of Patients With Knee Ostearthritis After IA Injection of Synvisc-one®
Status: COMPLETED
Conditions: Knee Osteoarthritis|Intra-Articular Injection
Interventions: DEVICE: Synvisc-One
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Sperm Selection Techniques on Human Neonatal Gender Ratio in Patients Undergoing ICSI
Status: COMPLETED
Conditions: Gender Ratio of ICSI Outcome
Interventions: OTHER: Density Gradient Centrifugation|DEVICE: Physiological ICSI|DEVICE: Magnetic Activated Cell Sorting
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Determining Optimal Post-Stroke Exercise (DOSE)
Status: COMPLETED
Conditions: Cerebrovascular Accident|Stroke|Cerebral Infarction|Brain Infarction|Brain Ischemia|Cerebrovascular Disorders|Brain Diseases|Central Nervous System Diseases|Nervous System Diseases|Vascular Diseases
Interventions: BEHAVIORAL: Stroke Management Program (SMP)|BEHAVIORAL: Stroke Monitoring Program (SMonP)|BEHAVIORAL: Stroke Supplementary Program (SSP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating the Efficacy and Safety of Lapatinib + Vinorelbine in ErbB2 Positive Metastatic Breast Cancer Patients
Status: TERMINATED
Conditions: Metastatic Breast Cancer
Interventions: DRUG: Lapatinib, Vinorelbine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of ERAS in LSG
Status: UNKNOWN
Conditions: Laparoscopic Sleeve Gastrectomy|Enhanced Recovery After Surgery|Pain, Postoperative|Nausea, Postoperative|Vomiting, Postoperative
Interventions: OTHER: ERAS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study of PEGASYS (Peginterferon Alfa-2a (40KD)) in Combination With Ribavirin in Patients With Chronic Hepatitis C (CHC) Previously Treated With PEG-Intron + Ribavirin
Status: COMPLETED
Conditions: Hepatitis C, Chronic
Interventions: DRUG: Ribavirin|DRUG: peginterferon alfa-2a [Pegasys]
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transdiagnostic Brain-Behavior Profiling to Enhance Cognitive Behavioral Therapy Response
Status: UNKNOWN
Conditions: Major Depressive Disorder|Social Anxiety Disorder
Interventions: BEHAVIORAL: CBT|BEHAVIORAL: ST
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of LY3972406 in Adult Participants With Moderate-to-Severe Plaque Psoriasis
Status: RECRUITING
Conditions: Plaque Psoriasis
Interventions: DRUG: LY3972406|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Reliability, Validity, and Responsiveness of the Timed 360° Turn Test in Patients With Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: OTHER: the timed 360° turn test|OTHER: Berg Balance Scale|OTHER: Four Square Step Test|OTHER: Functional Reach Test|OTHER: Trunk Impairment Scale|OTHER: Timed Up and Go Test|OTHER: Hoehn and Yahr Scale|OTHER: Unified Parkinson's Disease Rating Scale
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Systemic and Ocular Safety and Pharmacokinetics of BI 409306 in Patients With Schizophrenia, Alzheimer's Disease, and Healthy Volunteers
Status: COMPLETED
Conditions: Schizophrenia|Alzheimer Disease
Interventions: DRUG: Placebo matching BI 409306 25 mg|DRUG: Placebo matching BI 409306 50 mg|DRUG: BI 409306 25 mg|DRUG: BI 409306 50 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Post Stroke Hand Functions: Bilateral Movements and Electrical Stimulation Treatments
Status: COMPLETED
Conditions: Cerebrovascular Accident|Hemiplegia
Interventions: BEHAVIORAL: Bilateral movements and neuromuscular electrical stimulation|BEHAVIORAL: Bilateral movements and neuromuscular electrical stimulation|BEHAVIORAL: Bilateral movements and sham electrical stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Desflurane and Propofol on Quality of Recovery in Patients Undergoing Robotic or Laparoscopic Gastrectomy
Status: WITHDRAWN
Conditions: General Anesthesia
Interventions: DRUG: Desflurane|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Alogliptin Combined With Sulfonylurea in Subjects With Type 2 Diabetes Mellitus.
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: DRUG: Alogliptin and glyburide|DRUG: Alogliptin and glyburide|DRUG: Glyburide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Efficacy and Safety of P-3058 Nail Solution in the Treatment of Onychomycosis
Status: WITHDRAWN
Conditions: Onychomycosis of Toenail
Interventions: DRUG: P-3058 (terbinafine hydrochloride 10%)|DRUG: Vehicle of P-3058
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of TAK-783 in Subjects With Rheumatoid Arthritis
Status: COMPLETED
Conditions: Arthritis, Rheumatoid
Interventions: DRUG: TAK-783 and methotrexate|DRUG: Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: High-Dose Influenza Vaccine in Nursing Homes
Status: UNKNOWN
Conditions: Influenza
Interventions: BIOLOGICAL: HD Vaccine|BIOLOGICAL: SD Vaccine|BIOLOGICAL: Free Vaccine|BIOLOGICAL: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Genetic Test To Identify Previously Undetectable Minimal Residual Disease in Cell Samples From Younger Patients With Acute Lymphoblastic Leukemia
Status: COMPLETED
Conditions: Leukemia
Interventions: GENETIC: cytogenetic analysis|GENETIC: nucleic acid sequencing|OTHER: diagnostic laboratory biomarker analysis|OTHER: laboratory biomarker analysis|OTHER: medical chart review
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Chronic Leucine Supplemetion on Glucose Homeostasis, Body Compositin, Muscle Mass and Strength of Healthy and Young Subjects
Status: SUSPENDED
Conditions: Effect of Chronic Leucine Supplementation on Glucose Homeostasis, Lipid Profile, Body Composition, and Muscle Mass and Strenght
Interventions: DIETARY_SUPPLEMENT: Leucine|DIETARY_SUPPLEMENT: Alanine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Cannabinoids on Spasticity and Neuropathic Pain in Spinal Cord Injured Persons
Status: COMPLETED
Conditions: Muscle Spasticity as a Result of Spinal Cord Injury
Interventions: DRUG: nabilone 0.5 mg|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Developing a Decision Instrument to Guide Abdominal-pelvic CT Imaging of Blunt Trauma Patients
Status: RECRUITING
Conditions: Abdominal Injury|Pelvic Fracture|Genital Hemorrhage|Lumbar Spine Injury|Hip Injuries|Liver Injury|Spleen Injury|Renal Injury|Diaphragm Injury|Aortic Rupture|Aortic Dissection|Bowel Disease|Vascular System Injuries|Sacral Fracture
Interventions: OTHER: There are no interventions associated with this study
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Acute Effect of Sildenafil on Exercise Tolerance and Functional Capacity in COPD, IPF and Post Pneumonectomy Patients
Status: UNKNOWN
Conditions: Chronic Obstructive Pulmonary Disease|Idiopathic Pulmonary Fibrosis
Interventions: DRUG: Sildenafil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of OCA in Combination With BZF Evaluating Efficacy, Safety and Tolerability in Participants With PBC
Status: ACTIVE_NOT_RECRUITING
Conditions: Primary Biliary Cholangitis
Interventions: DRUG: Bezafibrate 100 mg|DRUG: Bezafibrate 200 mg|DRUG: Obeticholic Acid 5 mg|DRUG: Obeticholic Acid placebo|DRUG: Bezafibrate Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Vitamin d Deficiency in Chronic Rhinosinusitis With Nasal Polyposis
Status: UNKNOWN
Conditions: Vitamin D Deficiency, Nasal Polyposis
Interventions: DRUG: vitamin D supplementation|DRUG: usual therapy for nasal polyposis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Impact of Age-dependent Haptoglobin Deficiency on Plasma Free Hemoglobin Levels During Extracorporeal Membrane Oxygenation Support
Status: ACTIVE_NOT_RECRUITING
Conditions: Respiratory Failure
Interventions: DIAGNOSTIC_TEST: Plasma Haptoglobin Concentration
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: CC-5013 (Lenalidomide) and Rituximab in Waldenstrom's Macroglobulinemia
Status: TERMINATED
Conditions: Waldenstrom's Macroglobulinemia
Interventions: DRUG: CC-5103 (lenalidomide)|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acceptance and Commitment Therapy in Improving Well-Being in Patients With Stage III-IV Cancer and Their Partners
Status: COMPLETED
Conditions: Malignant Female Reproductive System Neoplasm|Malignant Hepatobiliary Neoplasm|Partner|Stage III Breast Cancer|Stage III Cervical Cancer|Stage III Colorectal Cancer|Stage III Lung Cancer|Stage III Prostate Cancer|Stage III Skin Melanoma|Stage III Uterine Corpus Cancer|Stage IIIA Breast Cancer|Stage IIIA Cervical Cancer|Stage IIIA Colorectal Cancer|Stage IIIA Lung Carcinoma|Stage IIIA Skin Melanoma|Stage IIIA Uterine Corpus Cancer|Stage IIIB Breast Cancer|Stage IIIB Cervical Cancer|Stage IIIB Colorectal Cancer|Stage IIIB Lung Carcinoma|Stage IIIB Skin Melanoma|Stage IIIB Uterine Corpus Cancer|Stage IIIC Breast Cancer|Stage IIIC Colorectal Cancer|Stage IIIC Skin Melanoma|Stage IIIC Uterine Corpus Cancer|Stage IV Breast Cancer|Stage IV Cervical Cancer|Stage IV Colorectal Cancer|Stage IV Lung Cancer|Stage IV Prostate Cancer|Stage IV Skin Melanoma|Stage IV Uterine Corpus Cancer|Stage IVA Cervical Cancer|Stage IVA Colorectal Cancer|Stage IVA Uterine Corpus Cancer|Stage IVB Cervical Cancer|Stage IVB Colorectal Cancer|Stage IVB Uterine Corpus Cancer
Interventions: BEHAVIORAL: Cognitive Behavior Therapy|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration|OTHER: Survey Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Dezocine Combined With Sufentanil on the Quality of Postoperative Recovery and Analgesic Effect in Patients Undergoing Thoracic Surgery
Status: RECRUITING
Conditions: Rehabilitation|Postoperative Pain
Interventions: DRUG: Dezocine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Motivational Refinements for Facilitating Reinforcement Schedule Thinning
Status: RECRUITING
Conditions: Decreasing Destructive Behavior|Increasing Functional Communicative Behavior
Interventions: BEHAVIORAL: Traditional Schedule Thinning|BEHAVIORAL: PIA-Informed Schedule Thinning|BEHAVIORAL: PIA-Informed Schedule Thinning with Competing Stimuli
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: APIC-CF Therapy for Mild to Moderate Osteoarthritis of the Knee
Status: UNKNOWN
Conditions: Pain|Osteoarthritis
Interventions: DEVICE: APIC-CF, 4 cc|DEVICE: APIC-CF, 2 cc|OTHER: Placebo Comparator: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Study to Characterize the Safety and Pharmacokinetics of Single Intravenous Dose of Lorazepam in Healthy Japanese Adult Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Lorazepam|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Role of Negr1 In Modulating Neuroplasticity in Major Depression (RONIN)
Status: RECRUITING
Conditions: Major Depressive Disorder|Bipolar Affective Disorder, Currently Depressed, Moderate
Interventions: DRUG: Venlafaxine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy With Trastuzumab in Treating Women With Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: BIOLOGICAL: trastuzumab|DRUG: CMF regimen|DRUG: cyclophosphamide|DRUG: fluorouracil|DRUG: methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: More Time Better Outcome - a Randomised Trial to Investigate the Effect of More Dietetic Time in Dialysis Patients
Status: COMPLETED
Conditions: Renal Failure
Interventions: BEHAVIORAL: additional review by dietician
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Using MRI to Visualize Regional Therapy Response in Idiopathic Pulmonary Fibrosis
Status: COMPLETED
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: DRUG: Hyperpolarized 129-Xenon gas|DEVICE: MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Sorafenib and Isolated Limb Infusion of Melphalan in Treating Patients With Stage III Melanoma of the Arm or Leg
Status: COMPLETED
Conditions: Melanoma (Skin)
Interventions: DRUG: melphalan|DRUG: sorafenib tosylate|GENETIC: gene expression analysis|GENETIC: protein expression analysis|GENETIC: western blotting|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized Controlled Trial of Nicotinamide Riboside Supplementation in Early Parkinson's Disease
Status: RECRUITING
Conditions: Parkinson Disease
Interventions: DIETARY_SUPPLEMENT: Nicotinamide Riboside|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Two Way Cross Over BE Fasting Pilot Study of Ropinirole Hydrochloride CR 2mg Tablets
Status: COMPLETED
Conditions: Pharmacokinetic Study
Interventions: DRUG: Test Product (Ropinirole)|DRUG: Reference Product (REQUIP )
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Effect of Virtual Glasses on Pain and Comfort During ESWL
Status: NOT_YET_RECRUITING
Conditions: Extracorporeal Shock Wave Lithotripsy|Lithotripsy
Interventions: BEHAVIORAL: ESWL Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: iTBS Study for Depression (Randomized)
Status: COMPLETED
Conditions: Executive Dysfunction|Depression
Interventions: DEVICE: Intermittent Theta Burst Stimulation|DEVICE: sham stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tenofovir Disoproxil Fumarate (Tenofovir DF) Versus Emtricitabine/Tenofovir DF in Subjects Resistant to Lamivudine
Status: COMPLETED
Conditions: Hepatitis B
Interventions: DRUG: TDF|DRUG: FTC/TDF|DRUG: TDF Placebo|DRUG: FTC/TDF Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: MDMA-Assisted Psychotherapy for Anxiety Associated With a Life-Threatening Illness
Status: COMPLETED
Conditions: Anxiety
Interventions: DRUG: MDMA (125 mg)|DRUG: Placebo|BEHAVIORAL: Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT