pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Effect of Transcranial Near InfraRed Light On Cerebral Function in Young and Healthy Older Subjects: a fMRI Study (TIROC)
Status: RECRUITING
Conditions: Healthy Volunteers
Interventions: DEVICE: ACTIVE Transcranial photobiomodulation (tPBM)|DEVICE: SHAM Transcranial photobiomodulation (tPBM)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Effect on the Electrocardiographic QT Interval Corrected for Heart Rate (QTc) in Healthy Subjects
Status: COMPLETED
Conditions: Alzheimer Disease
Interventions: DRUG: BMS-708163|DRUG: BMS-708163|DRUG: Placebo|DRUG: Moxifloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Tear Osmolarity Clinical Utility in Dry Eye Disease
Status: COMPLETED
Conditions: Dry Eye
Interventions: OTHER: Tear supplement|OTHER: Tear supplement 2|DIETARY_SUPPLEMENT: Omega 3 nutrition supplement|DEVICE: Eye bag|OTHER: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Carotenoid Bioavailability From Fresh Papaya, Tomato and Carrot
Status: COMPLETED
Conditions: Focus of Study: Carotenoid Absorption
Interventions: OTHER: Papaya|OTHER: Carrot|OTHER: Tomato
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of Early Relapsed, Lenalidomide-refractory Subjects Eligible for Carfilzomib Triplet
Status: ACTIVE_NOT_RECRUITING
Conditions: Relapsed or Refractory Multiple Myeloma
Interventions: DRUG: Carfilzomib|DRUG: Dexamethasone|DRUG: Pomalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Piloting Virtual Reality Environments to Treat PTSD in Healthcare Workers and Patients Consequent to the COVID-19 Pandemic
Status: RECRUITING
Conditions: Posttraumatic Stress Disorder
Interventions: BEHAVIORAL: Virtual Reality Exposure Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: External Compression Therapy for Secondary Prevention of Lower-Limb Loss and Cardiovascular Mortality
Status: UNKNOWN
Conditions: Critical Limb Ischemia
Interventions: DEVICE: ArtAssist© Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial to Evaluate the Safety and Efficacy of oNKord® in Subjects With Acute Myeloid Leukemia
Status: UNKNOWN
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Cyclophosphamide-Fludarabine (Cy/Flu)|DRUG: oNKord®
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Understanding Your Baby: A Parallel Group Study of a Universal Parenting Support Program
Status: ACTIVE_NOT_RECRUITING
Conditions: First-time Mothers and Their Partners
Interventions: BEHAVIORAL: Understanding Your Baby|BEHAVIORAL: Postnatal care as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: "Consultation Liaison and Integrated Care for COPD Patients With Psychiatric Co-Morbidity"
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease|Anxiety|Depression
Interventions: PROCEDURE: Integrated care|PROCEDURE: Usual control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Safety and Efficacy Study of NovoRapid™ in Patients With Coexisting Diabetes and Kidney Disease
Status: WITHDRAWN
Conditions: Diabetes|Diabetes Mellitus, Type 1|Diabetes Mellitus, Type 2|Chronic Kidney Disease
Interventions: DRUG: insulin aspart
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of a GnRH Injection on Ghrelin Concentrations in Girls With Suspected Premature Puberty
Status: COMPLETED
Conditions: Puberty, Precocious
Interventions: DRUG: Gonadotropin releasing hormone (GnRH)|DRUG: Sodium Chloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Enhancing Community Capacity to Improve Cancer Care Delivery
Status: COMPLETED
Conditions: End of Life|Cancer
Interventions: BEHAVIORAL: Program participants|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study of T-DXd Monotherapy in Patients With HER2-expressing Locally Advanced or Metastatic Gastric or GEJ Adenocarcinoma Who Have Received 2 or More Prior Regimens
Status: COMPLETED
Conditions: Gastric or Gastroesophageal Junction (GEJ) Adenocarcinoma
Interventions: DRUG: Trastuzumab Deruxtecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Use of Low-Dose Botulinum Toxin Injection Into the Masseter Muscle to Treat Sleep Bruxism
Status: COMPLETED
Conditions: Nocturnal Bruxism
Interventions: DRUG: BOTOX® Injection|OTHER: Prick skin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Effect of Aminophylline, Magnesium Sulphate and Placebo in Prevention of Post Dural Puncture Headache in Parturient Undergoing Caesarean Section.
Status: NOT_YET_RECRUITING
Conditions: Post-Dural Puncture Headache
Interventions: DRUG: Aminophylline , magnesium sulphate and placebo
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Intravenous Erythromycin on Gastric Emptying in Non-fasted Patients Before Emergency Total Anesthesia
Status: COMPLETED
Conditions: Aspiration of Gastric Contents|Gastric Emptying
Interventions: DRUG: Placebo|DRUG: Erythromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Determine the Effects of PF-04965842 on the Pharmacokinetics of Oral Contraceptive Steroids in Healthy Female Subjects
Status: COMPLETED
Conditions: Healthy Females
Interventions: DRUG: PF-04965842|DRUG: Ethinyl estradiol (EE) and levonorgestrel (LN)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Low Back Pain: Unveiling the Contribution of Motor Control Adaption Using Biomechanical Modeling and Neuroimaging
Status: COMPLETED
Conditions: Low Back Pain
Interventions: OTHER: mechanical stimulation|OTHER: vibrotactile stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Erector Spinae Catheter Versus Paravertebral Catheter for Postoperative Analgesia in Cancer Patients Post Mastectomies
Status: RECRUITING
Conditions: Post Operative Pain
Interventions: PROCEDURE: ERECTOR SPINAE PLANE BLOCK and PARAVERTEBRAL BLOCK:|PROCEDURE: PARAVERTEBRAL BLOCK:
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Consistency Study of Three Lots of Henogen's Adjuvanted Hepatitis B Vaccine When Given in 0, 1 Month Schedule
Status: COMPLETED
Conditions: Hepatitis B
Interventions: BIOLOGICAL: Adjuvanted Hepatitis B vaccine Lot 1|BIOLOGICAL: Adjuvanted Hepatitis B vaccine Lot 2|BIOLOGICAL: Adjuvanted Hep B vaccine Lot 3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Exercise Therapy Adjuvant Device on Head and Neck Cancer Patients in the Treatment of Cancer Therapy Induced Trismus
Status: UNKNOWN
Conditions: Maximum Interincisal Opening
Interventions: BEHAVIORAL: exercise therapy plus jaw device|BEHAVIORAL: exercise therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Immunogenicity and Safety of the 2011-2012 Vaccine Against Seasonal Influenza on Pregnant Women
Status: UNKNOWN
Conditions: Pregnancy|Investigation or Care in A Nonpregnant Woman
Interventions: BIOLOGICAL: Seasonal influenza vaccination
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Chlorhexidine Dressings for Hemodialysis Catheter Exit Site Care: Comparative Study
Status: COMPLETED
Conditions: Hemodialysis Catheter Infection
Interventions: DEVICE: Group "chlorhexidine dressing"|OTHER: Group "solution"
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study To Investigate If Embody's Retinol Gummies Improve The Early Signs Of Skin Aging And Overall Skin Health
Status: COMPLETED
Conditions: Acne, Adult
Interventions: DIETARY_SUPPLEMENT: Retinol gummy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Identification and Characterization of the Biomarker in Synovial Fluid for Hyaluronic Acid Therapy in Osteoarthritis
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: OTHER: proteomic analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: An Efficacy and Safety Study of PROCRIT (Epoetin Alfa) in Cancer Patients Receiving Chemotherapy Every Three Weeks
Status: COMPLETED
Conditions: Cancer|Anemia
Interventions: DRUG: Epoetin alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Biodistribution, Pharmacokinetics, and Safety of F-18 THK-5351 PET in Alzheimer's Disease Patients and Healthy Subjects.(Positron Emission Tomograph )
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: F-18 THK-5351
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Switch-Maintenance Gemcitabine After First-Line Chemotherapy In Patients With Malignant Pleural Mesothelioma
Status: COMPLETED
Conditions: Malignant Pleural Mesothelioma
Interventions: DRUG: Gemcitabine|OTHER: supportive care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EFFECT OF TREADMILL TRAINING ON BALANCE AFTER CHEMOTHERAPY IN CHILDREN WITH ACUTE LYMPHOBLASTIC LEUKEMIA
Status: COMPLETED
Conditions: Acute Lymphoblastic Leukemia, Pediatric
Interventions: OTHER: Balance exrcises|OTHER: Balance exrcises and Treadmill training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: An Online Compassionate Imagery Intervention for Veterinarian Mental Health
Status: COMPLETED
Conditions: Compassion|Perfectionism|Rumination|Self-Criticism|Resilience
Interventions: OTHER: Online Compassionate Imagery Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Pimecrolimus Cream 1% in Mild to Moderate Head and Neck Atopic Dermatitis (AD) Patients
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: Pimecrolimus|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Factors Influencing the Fecal Relative Abundance of ESBL-producing Enterobacteriaceae in Intensive Care (BLSE-REA).
Status: UNKNOWN
Conditions: ESBL-producing Enterobacteriaceae Infections
Interventions: OTHER: Evaluation of fecal RA and environmental contamination of ESBL-PE carrier in ICU
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Trial of Two Daclizumab Dosing Strategies vs. No Induction Treatment With Tacrolimus, Mycophenolate Mofetil , & Steroids for the Prevention of Acute Allograft Rejection in Simultaneous Kidney/Pancreas Transplant Recipients
Status: COMPLETED
Conditions: Acute Allograft Rejection in Simultaneous Kidney/Pancreas Transplant Recipients
Interventions: DRUG: Daclizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluation of the API-VIGIE Monitoring System: Program to Reduce Emergency Visits for Severe Paroxysmal Alcoholism
Status: WITHDRAWN
Conditions: Intoxication;Alcohol;Acute|Emergencies
Interventions: OTHER: Medical Outcomes Study Short Form 36 (SF 36)|OTHER: observationnal study
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Tolerability and Efficacy of L-Serine in Patients With Amyotrophic Lateral Sclerosis (ALS)
Status: TERMINATED
Conditions: Amyotrophic Lateral Sclerosis (ALS)
Interventions: DRUG: L-Serine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Half Swaddling and Kangaroo Care Practices on Maternal Sleep Quality and Postpartum Depression in Term Babies
Status: RECRUITING
Conditions: Mothers|Postpartum Depression
Interventions: OTHER: Half swaddle|OTHER: Kangaroo care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Haploidentical Transplant With NK Cell Infusion for Pediatric Acute Leukemia and Solid Tumors
Status: TERMINATED
Conditions: Leukemia|Solid Tumors
Interventions: DEVICE: Clinimacs Cell Separation System|DRUG: conditioning chemotherapy|OTHER: DLI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bortezomib in Treating Children With Advanced Solid Tumors
Status: COMPLETED
Conditions: Unspecified Childhood Solid Tumor, Protocol Specific
Interventions: DRUG: bortezomib|OTHER: laboratory biomarker analysis|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Carboplatin and Gemcitabine on Stage IIIB Pleural Effusion and Stage IV Lung Cancer
Status: COMPLETED
Conditions: Stage IV Non-small Cell Lung Cancer|Stage IIIB Non-small Cell Lung Cancer
Interventions: DRUG: Gemcitabine|DRUG: Dexamethasone|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of phoSPHocreatine on mEdical Emergency Team (Met) tREated Patients
Status: NOT_YET_RECRUITING
Conditions: Hypotension|Consciousness, Level Altered|Airway Disease|Respiratory Failure|Tachypnea|Bradypnea|Tachycardia|Bradycardia|Cardiac Failure|Cardiac Arrest
Interventions: DRUG: Phosphocreatine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Exploratory Safety and Effectiveness Evaluation of Pulsed Field Ablation (PFA) by Balloon Catheter With TRUPULSE Generator for Treatment of Paroxysmal Atrial Fibrillation (PAF)
Status: WITHDRAWN
Conditions: Atrial Fibrillation
Interventions: DEVICE: Pulsed Field Ablation by a Balloon Catheter with the TRUPULSE Generator
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Pharmacokinetics, Safety and Tolerability of IN-C009 in Healthy Subjects
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: DRUG: FCDP, dapagliflozin 10mg/linagliptin 5 mg or co-administration of a single dose of dapagliflozin and linagliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reduced Radiotherapy With Pac/Cis vs Standard Radiotherapy With 5-FU/Cis in Locally Advanced Head and Neck Cancer
Status: TERMINATED
Conditions: Head and Neck Cancer
Interventions: DRUG: Paclitaxel/Cisplatin|RADIATION: Reduced RT|DRUG: 5-FU/Cisplatin|RADIATION: Standard RT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of LY3009120 in Participants With Advanced Cancer or Cancer That Has Spread to Other Parts of Their Body
Status: TERMINATED
Conditions: Neoplasms|Neoplasm Metastasis|Melanoma|Carcinoma, Non-Small-Cell Lung|Colorectal Neoplasms
Interventions: DRUG: LY3009120 capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Study of Intravenous Iron Sucrose in Adolescents on Hemodialysis or Peritoneal Dialysis Receiving Epoetin
Status: COMPLETED
Conditions: Anemia
Interventions: DRUG: iron sucrose injection USP
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of a Timolol Nasal Spray as a Treatment for Epistaxis in Hereditary Hemorrhagic Telangiectasia (HHT) - (TEMPO)
Status: COMPLETED
Conditions: Telangiectasia, Hereditary Hemorrhagic|Osler Rendu Disease
Interventions: DRUG: Timolol nasal spray|DRUG: Placebo nasal spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Impact of Milk Protein Glycation on Protein Digestion and Absorption
Status: COMPLETED
Conditions: Protein Digestion & Absorption
Interventions: DIETARY_SUPPLEMENT: Low glycated milk protein|DIETARY_SUPPLEMENT: High glycated milk protein
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Influence of Probiotics on the Vaginal Microbiota
Status: COMPLETED
Conditions: Vaginal Microbiome
Interventions: DIETARY_SUPPLEMENT: OMNi-BiOTiC® FLORA plus+
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Can Patients With Atrial Fibrillation Safely Discontinue Anticoagulant Therapy After Cardiac Surgery? (ATLAAC)
Status: RECRUITING
Conditions: Atrial Fibrillation|Left Atrial Appendage Absent|Anticoagulant Adverse Reaction
Interventions: DRUG: OAC will be discontinued for the duration of the trial
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigating Orthobiologics After PRP and Photobiomodulation for Knee Osteoarthritis
Status: ACTIVE_NOT_RECRUITING
Conditions: Knee Osteoarthritis
Interventions: OTHER: Physical Therapy|BIOLOGICAL: Platelet-Rich Plasma Injection|DEVICE: Photobiomodulation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment for Patients With Osteoarthritis (OA) of the Knee
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DRUG: Intra-articular metHuIL-1ra (anakinra)|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial to Evaluate the Safety and Efficacy of ZYH7 Compared to Fenofibrate in Patients With Dyslipidemia
Status: COMPLETED
Conditions: Hypertriglyceridemia|Dyslipidemia
Interventions: DRUG: ZYH7|DRUG: ZYH7|DRUG: ZYH7|DRUG: Fenofibrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: FOLFIRI + Panitumumab First-line Treatment in Elderly Patients With Unresectable Metastatic Colorectal Cancer, RAS/BRAF Wild-type and Good Performance Status
Status: COMPLETED
Conditions: Colorectal Neoplasms|Colorectal Carcinoma|Colorectal Cancer Metastatic|Neoplasm Metastasis
Interventions: DRUG: Panitumumab|DRUG: Irinotecan|DRUG: Folinic acid|DRUG: 5-FU
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Simplified EEG Monitoring Tool With Standard EEG Monitoring in Patients With Acute Neurological Insult
Status: UNKNOWN
Conditions: Acute Neurological Insult
Interventions: DEVICE: Bispectral index (BIS) EEG monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: PTA vs. Primary Stenting of SFA Using Self-Expandable Nitinol Stents
Status: COMPLETED
Conditions: Peripheral Vascular Diseases|Intermittent Claudication|Angioplasty
Interventions: DEVICE: Nitinol stent|PROCEDURE: Nitinol Stent Placement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Enhanced Control of Hypertension and Thrombolysis Stroke Study (ENCHANTED)
Status: COMPLETED
Conditions: Ischemic Stroke|High Blood Pressure
Interventions: DRUG: Low-dose rtPA|DRUG: Standard-dose rtPA|OTHER: Intensive blood pressure (BP) lowering|OTHER: BP management policies
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Acute Ischemic Stroke (ReMEDy2 Trial)
Status: RECRUITING
Conditions: Acute Stroke|Ischemic Stroke|Stroke
Interventions: DRUG: Recombinant human tissue kallikrein
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: MT10109L in the Treatment of Glabellar Lines (GL) With or Without Concurrent Treatment of Lateral Canthal Lines (LCL)
Status: COMPLETED
Conditions: Glabellar Lines|Lateral Canthal Lines
Interventions: DRUG: MT10109L|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PET Scans in Patients With Head And Neck Cancer Who Are Undergoing 3-Dimensional Conformal Radiation Therapy And Intensity-Modulated Radiation Therapy
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: RADIATION: 3-dimensional conformal radiation therapy|RADIATION: fludeoxyglucose F 18|RADIATION: intensity-modulated radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Biological Skin Graft With Keratinocyte-stem Cell Co-cultre for Burn Patients
Status: RECRUITING
Conditions: Burn Degree Second|Burn Degree Third
Interventions: PROCEDURE: Split-thickness skin graft|BIOLOGICAL: Artificial skin graft|BIOLOGICAL: Artificial skin graft co-culture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Ziprasidone to Treat Depressive Symptoms in Patients With Schizophrenia
Status: UNKNOWN
Conditions: The Primary Evaluation is the Change From Baseline at End of Study for CDSS Total Scores.|The Secondary Efficacy Evaluations Include: MADRS, PANSS Total Scores and Subscales and Responder Rate; CGI-S and CGI-I Scales.|Safety Evaluations Include: Laboratory Test Abnormalities; BARS and SAS; Physical Examinations; Vital Signs; Electrocardiogram,Etc.|Subjective Well-being Under Neuroleptics Short Form Will be Used in Our Study to Assess the Subjective Side-effects.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Mobile Health Intervention in Pulmonary Arterial Hypertension
Status: COMPLETED
Conditions: Pulmonary Arterial Hypertension|Idiopathic Pulmonary Arterial Hypertension|Heritable Pulmonary Arterial Hypertension|Associated Pulmonary Arterial Hypertension
Interventions: DEVICE: Smartphone Text Messaging|DEVICE: Fitbit Charge HR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Pharmacological Antilipolysis on the Metabolic Effects of Ghrelin
Status: COMPLETED
Conditions: Metabolism|Insulin Resistance|Hypopituitarism
Interventions: DRUG: Acipimox|DRUG: Ghrelin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Excretion Balance, PK and Metabolism of a Single Oral Dose of [14C]PCO371
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: PCO371|DRUG: [14C]PCO371|DRUG: [14C]PCO371
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies
Status: TERMINATED
Conditions: Acute Biphenotypic Leukemia|Acute Erythroid Leukemia in Remission|Acute Leukemia in Remission|Acute Lymphoblastic Leukemia in Remission|Acute Myeloid Leukaemia With Prior Myelodysplastic Syndrome|Acute Myeloid Leukemia in Remission|Acute Myeloid Leukemia With FLT3/ITD Mutation|Acute Myeloid Leukemia With Inv(3)(Q21Q26.2); RPN1-EVI1|Acute Myeloid Leukemia With Multilineage Dysplasia|Acute Myeloid Leukemia With t(6;9)|Acute Undifferentiated Leukemia|Adult Acute Lymphoblastic Leukemia in Complete Remission|B Acute Lymphoblastic Leukemia With T(1;19)(Q23;P13.3); E2A-PBX1 (TCF3-PBX1)|Ph+ ALL|Burkitt Lymphoma|Childhood Acute Lymphoblastic Leukemia in Complete Remission|DS Stage II Plasma Cell Myeloma|DS Stage III Plasma Cell Myeloma|Myelodysplastic Syndrome|Recurrent Anaplastic Large Cell Lymphoma|Blasts Under 5 Percent of Bone Marrow Nucleated Cells|Recurrent Follicular Lymphoma|Recurrent Hodgkin Lymphoma|Recurrent Mantle Cell Lymphoma|Recurrent Marginal Zone Lymphoma|Recurrent Plasma Cell Myeloma|Refractory Plasma Cell Myeloma|Secondary Acute Myeloid Leukemia|T Lymphoblastic Lymphoma|Hematopoietic Cell Transplant Recipient
Interventions: DRUG: Cyclophosphamide|BIOLOGICAL: Filgrastim|DRUG: Fludarabine Phosphate|DRUG: Mycophenolate Mofetil|PROCEDURE: Nonmyeloablative Allogeneic Hematopoietic Stem Cell Transplantation|PROCEDURE: Peripheral Blood Stem Cell Transplantation|DRUG: Tacrolimus|RADIATION: Total-Body Irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity, Safety and Tolerability of a Plant-Derived Seasonal Virus-Like-Particle Quadrivalent Influenza Vaccine in Adults
Status: COMPLETED
Conditions: Virus Diseases|RNA Virus Infections|Respiratory Tract Diseases|Respiratory Tract Infections
Interventions: BIOLOGICAL: Low dose of quadrivalent VLP vaccine|BIOLOGICAL: Medium dose of quadrivalent VLP vaccine|BIOLOGICAL: High dose of quadrivalent VLP vaccine|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Bavituximab With Radiation and Temozolomide for Patients With Newly Diagnosed Glioblastoma
Status: COMPLETED
Conditions: Glioblastoma
Interventions: DRUG: Temozolomide|DRUG: Bavituximab|RADIATION: Radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Quality of Life Study About the Role of Turbinectomy in Rhinoseptoplasty
Status: COMPLETED
Conditions: Deviated Nasal Septum|Nasal Septal Defect|Nasal Septum, Irregular
Interventions: PROCEDURE: Rhinoseptoplasty|PROCEDURE: Partial turbinectomy|PROCEDURE: Endoscopic partial turbinectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: DART II - A Phase IV Study of 3 Antiretroviral Medicines in Combination, in HIV Patients Who Have Not Been Previously Treated With Antiretroviral Therapy
Status: COMPLETED
Conditions: HIV Infections|AIDS
Interventions: DRUG: efavirenz, stavudine extended release, lamivudine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Effect of Hepatic Impairment on the Pharmacokinetics, Safety and Tolerability of ASP2215
Status: COMPLETED
Conditions: Hepatic Impairment|Healthy
Interventions: DRUG: ASP2215
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effectiveness of PEA Compared to Placebo on Acute Menstrual Pain
Status: RECRUITING
Conditions: Menstrual Pain
Interventions: DRUG: Levagen+|DRUG: Microcrystalline cellulose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Caries Arrested & Prevented Among SDF, NaF Varnish and Combination in Children
Status: COMPLETED
Conditions: Dental Caries in Children|Satisfaction|Cost Effectiveness|Oral Health|Quality of Life
Interventions: DEVICE: SDF|DEVICE: Fluoride varnish
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An Investigation of the Effect of Types of Catheters on Bloodstream Infection in Patients With Major Burns: Prediction With Procalcitonin and Prognosis
Status: COMPLETED
Conditions: Burns
Interventions: DIAGNOSTIC_TEST: Patients' procalcitonin, thrombocyte, and leukocyte levels were assessed every other day for 4 weeks, beginning on the first day they were admitted to the burn center.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Olopatadine Hydrochloride Ophthalmic Solution Study in Chinese Subjects
Status: COMPLETED
Conditions: Allergic Conjunctivitis
Interventions: DRUG: Olopatadine Hydrochloride Ophthalmic Solution 0.2%|DRUG: Olopatadine Hydrochloride Ophthalmic Solution 0.1%|DRUG: Olopatadine 0.2% Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cx611-0101, eASCs Intravenous Administration to Refractory Rheumatoid Arthritis Patients
Status: COMPLETED
Conditions: Rheumatoid Arthritis Aggravated
Interventions: GENETIC: Stem cells|GENETIC: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Combination of Durvalumab and Tremelimumab as Maintenance Treatment in Patients With Non Squamous and Squamous (NSCLC)
Status: WITHDRAWN
Conditions: Squamous Non-small Cell Lung Cancer|Non-Squamous Non-small Cell Lung Cancer
Interventions: DRUG: Durvalumab|DRUG: Tremelimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Rebif® in Subjects With Relapsing Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis, Relapsing-Remitting
Interventions: DRUG: Rebif®|DRUG: Rebif®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Psychoeducation for Hepatitis and Alcohol Behaviors
Status: COMPLETED
Conditions: Hepatitis C|Substance Abuse
Interventions: BEHAVIORAL: Family-Responsive Psychoeducation Program (PERF)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Efficacy of the WaisFix100i for Intracapsular Femoral Fracture Fixation
Status: SUSPENDED
Conditions: Hip Fracture
Interventions: DEVICE: Intracapsular Femoral Fracture Fixation|DEVICE: WaisFix100i for Intracapsular Femoral Fracture Fixation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Moderate Intensity Soleus Pushups Versus Sustained Soleus Pushups on Blood Glucose Level Among Young Population
Status: RECRUITING
Conditions: Health Behavior
Interventions: BEHAVIORAL: Short Duration Moderate Intensity Soleus Push-ups|BEHAVIORAL: Sustained Soleus Push-ups
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Functional Instability in Patients Suffering From Collagen Disease and Joint Hypermobility
Status: RECRUITING
Conditions: Hypermobility Syndrome|Danlos Disease, Ehlers|Collagen Diseases|Joint Hypermobility|Laxity of Ligament
Interventions: DIAGNOSTIC_TEST: Clinical tests and balance evaluation using the Delos Proprioceptive System
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study to Assess Rifaximin Soluble Solid Dispersion (SSD) for the Delay of Encephalopathy Decompensation in Cirrhosis
Status: ACTIVE_NOT_RECRUITING
Conditions: Hepatic Encephalopathy
Interventions: DRUG: Rifaximin SSD|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Recombinant Human B Lymphocyte(RC18) Administered Subcutaneously to Subjects With Systemic Lupus Erythematosus(SLE)
Status: COMPLETED
Conditions: Systemic Lupus Erythematosus
Interventions: BIOLOGICAL: Placebo plus standard therapy|BIOLOGICAL: RC18 160 mg plus standard therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vascular Effect of Estrogens Versus Placebo Evaluated by Flow-mediated Dilatation of Brachial Artery
Status: COMPLETED
Conditions: Unspecified Injury of Brachial Artery, Left Side, Initial Encounter
Interventions: DRUG: Estrogens, Conjugated (USP)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Safety and Efficacy Study of Farletuzumab in Participants With Adenocarcinoma of the Lung
Status: COMPLETED
Conditions: Adenocarcinoma of the Lung
Interventions: BIOLOGICAL: Farletuzumab|OTHER: Placebo|DRUG: Carboplatin|DRUG: Paclitaxel|DRUG: Pemetrexed|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ruptured Aorta-iliac Aneurysms: Endo vs. Surgery
Status: COMPLETED
Conditions: Ruptured Aorta-iliac Aneurysms
Interventions: PROCEDURE: Endovascular repair
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Families With an Hemopathies Predisposition Related to the DDX41 Gene.
Status: RECRUITING
Conditions: DDX41 Gene Mutation
Interventions: GENETIC: For each person (index case or related) included in this study:
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Effects of Social Media on Food Intake and Behaviour
Status: COMPLETED
Conditions: Sedentary Lifestyle|Hunger|Eating
Interventions: BEHAVIORAL: Facebook|BEHAVIORAL: Facebook + Food|BEHAVIORAL: Colouring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: FilmArray Pneumonia Panel for Antimicrobial Treatment of HAP/VAP in Intensive Care Units
Status: TERMINATED
Conditions: Pneumonia, Ventilator-Associated|Pneumonia, Hospital Acquired|Critically Ill
Interventions: DIAGNOSTIC_TEST: FilmArray Pneumonia panel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Cognitive Behavioral Therapy Plus Motivational Interviewing for Treatment of Obsessive-Compulsive Disorder
Status: COMPLETED
Conditions: Obsessive-Compulsive Disorder
Interventions: BEHAVIORAL: Motivational interviewing plus exposure and response prevention (MI plus EX/RP)|BEHAVIORAL: Exposure and response prevention (EX/RP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Inulin and the Gut Microbiota in Healthy Adults
Status: UNKNOWN
Conditions: Gut Microbiota Dysbiosis and Nutrition
Interventions: DIETARY_SUPPLEMENT: Inulin|DIETARY_SUPPLEMENT: Maltodextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Integrative Migraine Pain Alleviation Through Chiropractic Therapy
Status: COMPLETED
Conditions: Migraine|Migraine Disorders|Migraine With Aura|Migraine Without Aura|Migraine, Classic
Interventions: OTHER: Chiropractic Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Pharmacodynamics, Safety, Tolerability and Pharmacokinetics of MT-3995 in Type II Diabetic Nephropathy Subjects With Albuminuria and Moderately Decreased GFR
Status: COMPLETED
Conditions: Diabetic Nephropathy
Interventions: DRUG: MT-3995 Low|DRUG: MT-3995 High|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Hyperbaric Oxygen Therapy on Cerebral Palsy
Status: COMPLETED
Conditions: Cerebral Palsy|Hyperbaric Oxygen Therapy
Interventions: OTHER: Traditional Physical Therapy|DEVICE: Hyperbaric oxygen therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Tolerance and Satisfaction With CLOBEX® Spray When Used as Monotherapy or Add-on Therapy in Plaque Psoriasis
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: Clobetasol Propionate, 0.05%|DRUG: Clobetasol propionate, 0.05% Spray
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety of Grazax in Children
Status: COMPLETED
Conditions: Allergy
Interventions: BIOLOGICAL: Grazax-R|BIOLOGICAL: Grazax Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: GOIZ ZAINDU Feasibility Multi Domain Trial to Prevent Dementia.
Status: COMPLETED
Conditions: Cognitive Decline|Dementia Risk Factors|Prevention|Multidomain Intervention
Interventions: BEHAVIORAL: Multidomain intervention (MD-Int) group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Managing Diabetes in Pregnancy Using Cell Phone/Internet Technology
Status: COMPLETED
Conditions: Diabetes During Pregnancy|Gestational Diabetes
Interventions: DEVICE: Cell phone-internet home glucose reporting system|BEHAVIORAL: Voicemail home blood glucose reporting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: FREEDOM DR: Oral Treprostinil in Combination With an Endothelin Receptor Antagonist (ERA) and/or a Phosphodiesterase-5 (PDE-5) Inhibitor or as Monotherapy for the Treatment of Pulmonary Arterial Hypertension (PAH)
Status: WITHDRAWN
Conditions: Pulmonary Hypertension
Interventions: DRUG: UT-15C 1 mg|DRUG: UT-15C 0.25 mg|DRUG: UT-15C 5 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Memantine for the Treatment of Cognitive Dysfunction and Negative Symptoms in Patients With Chronic Schizophrenia
Status: TERMINATED
Conditions: Chronic Schizophrenia
Interventions: DRUG: Memantine|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Perioperative Intravenous Dexamethasone on Pain in Out Patient Knee Surgery
Status: TERMINATED
Conditions: Post Operative Pain|Nausea
Interventions: DRUG: Dexamethasone 8mg iv x1|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CAR-T Followed by Bispecific Antibodies
Status: RECRUITING
Conditions: Large B-cell Lymphoma|DLBCL - Diffuse Large B Cell Lymphoma
Interventions: DRUG: mosunetuzumab|DRUG: glofitamab|DRUG: obinutuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Platinum Plus Etoposide With or Without BGB-A317 in Participants With Untreated Extensive-Stage Small Cell Lung Cancer
Status: COMPLETED
Conditions: Small Cell Lung Cancer
Interventions: DRUG: Tislelizumab, Carboplatin /Cisplatin, Etoposide|DRUG: Carboplatin / Cisplatin, Etoposide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ruxolitinib in Estrogen Receptor Positive Breast Cancer
Status: COMPLETED
Conditions: Estrogen-receptor Positive Invasive Metastatic Breast Cancer
Interventions: DRUG: Ruxolitinib|DRUG: Exemestane
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Follow-up Study of Safety of Enteric-coated Mycophenolate Sodium in Patients Who Successfully Completed Study CERL080A0107
Status: COMPLETED
Conditions: Renal Transplant
Interventions: DRUG: Mycophenolate sodium (enteric coated)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prebiotic in Preterm Infants
Status: COMPLETED
Conditions: Preterm Infant|Development, Infant|Nutrition
Interventions: DIETARY_SUPPLEMENT: Prebiotic|DIETARY_SUPPLEMENT: Dextrose Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: CT Scan Compared to CXR and LUS in Pneumonia in the Elderly
Status: RECRUITING
Conditions: Pneumonia|Elderly Infection
Interventions: DIAGNOSTIC_TEST: Chest X-Ray (CXR)|DIAGNOSTIC_TEST: Low-dose CT scan (LDCT)|DIAGNOSTIC_TEST: Lung ultrasonography (LUS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficiency Study About the Effect of Acupuncture on Postoperative Pain After Total Knee Arthroplasty
Status: UNKNOWN
Conditions: Pain, Postoperative
Interventions: DEVICE: acupuncture/PCA/NSAID|DEVICE: sham acupuncture/PCA/NSAID|OTHER: PCA/NSAID
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Fat Analysis Trial (FAT) - Assessing the Impact of Lipo-aspirate Processing
Status: NOT_YET_RECRUITING
Conditions: Breast Asymmetry|Fat Atrophy
Interventions: DEVICE: Fat grafting - Revolve device|DEVICE: Fat grafting - Decantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Modifiable Variables in Parkinsonism (MVP)
Status: RECRUITING
Conditions: Parkinson's Disease|Parkinsonism|MSA - Multiple System Atrophy|Progressive Supranuclear Palsy|Shy-Drager Syndrome|Corticobasal Degeneration|Dementia With Lewy Bodies|Pick Disease|Olivopontocerebellar Atrophies
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Duloxetine on Postoperative Wound Complication of Total Knee Arthroplasty (TKA) in Central Sensitization Patients
Status: UNKNOWN
Conditions: Osteoarthritis, Knee
Interventions: DRUG: Duloxetine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ALS Diagnosis From a Saliva Sample: a Non-coding RNA Analysis Approach
Status: RECRUITING
Conditions: Amyotrophic Lateral Sclerosis, Sporadic|Amyotrophic Lateral Sclerosis
Interventions: DIAGNOSTIC_TEST: Saliva sample|DIAGNOSTIC_TEST: Saliva sample
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p