pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: High-intensity Interval Training on the Self-esteem, Basal Metabolic Rate and Muscle Mass in Overweight Women.
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: BEHAVIORAL: High-intensity interval training|BEHAVIORAL: Moderate-intensity continuous training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Nemolizumab in Subjects With Moderate-to-Severe Atopic Dermatitis
Status: COMPLETED
Conditions: Moderate-to-Severe Atopic Dermatitis
Interventions: DRUG: Placebo|DRUG: Nemolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety of 3 New 6:2 Influenza Virus Reassortants in Adults
Status: COMPLETED
Conditions: Influenza|Healthy
Interventions: BIOLOGICAL: Trivalent Influenza Vaccine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Closed-Loop Brain Stimulation as a Potential Intervention for Cognitive Decline
Status: RECRUITING
Conditions: Mild Cognitive Impairment
Interventions: DEVICE: Sham TBS|DEVICE: Closed-loop TBS|DEVICE: Open-loop TBS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Vildagliptin Plus Metformin (SPC) Treatment in Type 2 Diabetes Mellitus Patients
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Vildagliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Is Levocetirizine Less Sedating Than Cetirizine?
Status: COMPLETED
Conditions: Allergic Rhinitis
Interventions: DRUG: Cetirizine|DRUG: Levocetirizine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: High-Intensity Laser Therapy: Effectiveness on Knee Osteoarthritis Patients
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: OTHER: High Intensity Laser Therapy|OTHER: Transcutaneous Electrical Nerve Stimulation|OTHER: Hotpacks|OTHER: SHAM - High Intensity Laser Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy in Treating Men With Germ Cell Cancer
Status: UNKNOWN
Conditions: Extragonadal Germ Cell Tumor|Teratoma|Testicular Germ Cell Tumor
Interventions: BIOLOGICAL: bleomycin sulfate|BIOLOGICAL: filgrastim|DRUG: cisplatin|DRUG: etoposide|DRUG: paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of QiShen YiQi Dripping Pills in Chronic Heart Failure
Status: RECRUITING
Conditions: Chronic Heart Failure With Reduced Ejection Fraction
Interventions: DRUG: Low dose QiShen YiQi Dripping Pills 3 bags|DRUG: High dose QiShen YiQi Dripping Pills 3 bags|DRUG: QiShen YiQi Dripping Pills placebo 3 bags
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Relapsed or Refractory Acute Myeloblastic Leukemia
Status: COMPLETED
Conditions: Acute Myeloblastic Leukemia
Interventions: DRUG: fludarabine|DRUG: Idarubicin|DRUG: cytarabine|DRUG: G-CSF|DRUG: plerixafor
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TaKeTiNa in the Treatment of Depression: a Pilot Study.
Status: RECRUITING
Conditions: Major Depressive Disorder
Interventions: BEHAVIORAL: TaKeTiNa music therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Affection of Renal and Urinary System in IBD Patients
Status: NOT_YET_RECRUITING
Conditions: Nephrolithiasis, Glomerulonephritis, Amyloidosis,AKI, CKD, Tubuli Interstitial|Urinary System Disorders in IBD Patients
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Slow-release Melatonin (Circadin®) Therapy on Idiopathic RBD: a Pilot Study
Status: UNKNOWN
Conditions: REM Sleep Behavior Disorder
Interventions: DRUG: Circadin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Magnetic Resonance Whole Body Diffusion-Weighted Imaging in Finding Bone or Lymph Node Metastasis in Participants With High-Risk Prostate Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Carcinoma
Interventions: PROCEDURE: Bone Scan|PROCEDURE: Computed Tomography|PROCEDURE: Magnetic Resonance Imaging|PROCEDURE: Magnetic Resonance Whole Body Diffusion-Weighted Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Laryngeal Mask Airway for Adenoidectomies (LMAA)
Status: COMPLETED
Conditions: Adenoidectomy Surgery|Flexible-Laryngeal Mask Airway
Interventions: OTHER: Flexible-Laryngeal Mask Airway
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study of Cabozantinib (XL184) Versus Mitoxantrone Plus Prednisone in Men With Previously Treated Symptomatic Castration-resistant Prostate Cancer
Status: TERMINATED
Conditions: Prostate Cancer|Castration Resistant Prostate Cancer|Pain|Prostatic Neoplasms
Interventions: DRUG: cabozantinib|DRUG: mitoxantrone|DRUG: prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of SHR8028 Eye Drops for the Treatment of Dry Eye Disease
Status: COMPLETED
Conditions: Dry Eye Disease
Interventions: DRUG: SHR8028 eye drops|DRUG: Vehicle eye drops.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacies of The New Paclitaxel-Eluting CoroflexTM Please Stent in Percutaneous Coronary Intervention
Status: UNKNOWN
Conditions: Coronary Artery Disease
Interventions: DEVICE: Coroflex Please stent implantation|DEVICE: Taxus stent implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mometasone Furoate 0.1% Versus Eucerin on Moderate to Severe Skin Toxicities in Breast Cancer Patients Receiving Postmastectomy Radiation
Status: COMPLETED
Conditions: Invasive Breast Cancer
Interventions: OTHER: Eucerin|OTHER: Mometasone Furoate 0.1%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Phase IIA Clinical Trial to Evaluate the Efficacy of Ivermectin to Obtain Negative PCR Results in Patients With Early Phase COVID-19
Status: COMPLETED
Conditions: Covid19|Coronavirus Infection|SARS-CoV Infection
Interventions: DRUG: Ivermectin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the GORE® Ascending Stent Graft
Status: ENROLLING_BY_INVITATION
Conditions: Aortic Aneurysm, Thoracic|Pseudoaneurysm|Aortic Dissection|Aorta; Lesion
Interventions: DEVICE: GORE® Ascending Stent Graft (ASG device)|DEVICE: GORE® Thoracic Aortic Graft Thoracic Branch Endoprosthesis (TBE Device)|PROCEDURE: Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effects of Combining Cabazitaxel With Cisplatin Given Every 3 Weeks in Patients With Advanced Solid Cancer
Status: COMPLETED
Conditions: Solid Cancer
Interventions: DRUG: cabazitaxel (XRP6258)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acamprosate Added to Escitalopram and Behavioral Treatment for Comorbid Depression and Alcoholism
Status: COMPLETED
Conditions: Major Depressive Disorder|Alcohol Abuse|Alcohol Dependence
Interventions: DRUG: acamprosate|DRUG: escitalopram|BEHAVIORAL: Medical management|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Low-dose Lenalidomide for Non-severe COVID-19 Treatment Trial
Status: UNKNOWN
Conditions: COVID-19
Interventions: DRUG: Lenalidomide as a 5 mg capsule PO daily, days 1, 3, and 5.|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: AP23573 in Female Adult Patients With Recurrent or Persistent Endometrial Cancer (8669-019)(COMPLETED)
Status: COMPLETED
Conditions: Endometrial Cancer
Interventions: DRUG: ridaforolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Chemotherapy Combined With Immunocheckpoint Inhibitors in Advanced Biliary Malignancies
Status: UNKNOWN
Conditions: Gemcitabine|Biliary Tract Cancer|Immune Checkpoint Inhibitors
Interventions: DRUG: Gemcitabine-based chemotherapy regimen combined with immunocheckpoint inhibitors
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sublingual Immunotherapy in Children With Allergic Rhinitis
Status: COMPLETED
Conditions: Allergic Rhinitis
Interventions: BIOLOGICAL: Mite, Mite and Bacterial or Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 1b Study Evaluating ACY-1215 (Ricolinostat) in Combination With Pomalidomide and Dexamethasone in Relapsed or Relapsed-and-Refractory Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: ACY-1215 in combination with pomalidomide and dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Treatment Efficacy of OMT for Carpal Tunnel Syndrome
Status: COMPLETED
Conditions: Carpal Tunnel Syndrome
Interventions: PROCEDURE: Osteopathic Manipulative Treatment|PROCEDURE: Placebo Sub-Therapeutic Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial of Non-operative Versus Operative Management of Olecranon Fractures in the Elderly
Status: TERMINATED
Conditions: Olecranon Fractures in the Elderly
Interventions: OTHER: Non-operative|OTHER: Operative
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparative Study To Determine If Motivating Asthma Education (Compliance Enhancement) Has An Effect On Asthma Control
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: salmeterol/fluticasone propionate 50/250 µg + 3 training sessions of compliance enhancement training|DRUG: salmeterol/fluticasone propionate 50/250 µg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: LR769 in Congenital Hemophilia Patients With Inhibitors Undergoing Elective Surgery or Invasive Procedures
Status: COMPLETED
Conditions: Hemophilia
Interventions: BIOLOGICAL: Coagulation Factor VIIa (Recombinant)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics, Pharmacodynamics, And Safety Of Maraviroc (UK-427,857) In Patients With Human Immunodeficiency Virus
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Maraviroc (UK-427,857)|DRUG: Maraviroc (UK-427,857)|DRUG: Maraviroc (UK-427,857)|DRUG: Maraviroc (UK-427,857)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cognitive Behaviour Therapy (CBT) for Body Dysmorphic Disorder (BDD)
Status: COMPLETED
Conditions: Body Dysmorphic Disorder
Interventions: BEHAVIORAL: CBT specific for BDD|BEHAVIORAL: Non specific CBT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Safety and Tolerability of AEB071 Versus Cyclosporine in the Novo Renal Transplant Recipients
Status: COMPLETED
Conditions: Kidney Transplantation
Interventions: DRUG: AEB071|DRUG: Certican|DRUG: Neoral
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cook Balloon vs Dilapan-S for Outpatient Cervical Ripening
Status: COMPLETED
Conditions: Induced; Birth
Interventions: DEVICE: Dilapan-S|DEVICE: Cook Cervical Ripening Balloon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Phase III Randomized Trial of Thalidomide/Dexamethasone Versus Vincristine+Adriamycin+Dexamethasone (VAD)
Status: TERMINATED
Conditions: Multiple Myeloma
Interventions: DRUG: zoledronic acid|DRUG: dexamethasone|DRUG: thalidomide|DRUG: vincristine|DRUG: adriamycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Off-Label Medications for Alcohol Use Disorder Among Patients With HIV: Pilot Study 2
Status: NOT_YET_RECRUITING
Conditions: Alcohol Use Disorder|Hiv|Tobacco Use Disorder
Interventions: DRUG: Varenicline
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomised Clinical Trial Comparing Drug-coated Balloon to Plain Balloon for All Peripheral AVF Stenosis
Status: RECRUITING
Conditions: Arteriovenous Fistula|Arteriovenous Fistula Stenosis|Dialysis Access Malfunction
Interventions: DEVICE: Angioplasty of all peripheral AVF stenosis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Western Diet Patterns on Plasma Inflammatory and Cardio Metabolic Health Signatures in Middle-aged Adults
Status: COMPLETED
Conditions: Healthy Diet
Interventions: DIETARY_SUPPLEMENT: Traditional Diet|DIETARY_SUPPLEMENT: Modern Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Restriction of Dietary AGEs to Prevent Diabetes in Overweight Individuals
Status: COMPLETED
Conditions: Advanced Glycation Endproducts|AGEs|Diet|Insulin Sensitivity/Resistance|Beta-cell Function|Vascular Function
Interventions: OTHER: Diet low or high in advanced glycation endproducts
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Phase II Study of HY209 Gel for Atopic Dermatitis Patients (Shaperon)
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: HY209 0.3%|DRUG: HY209 0.5%|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Awareness Model in Prevention of Osteoporosis
Status: COMPLETED
Conditions: Osteoporosis|University Students|Healthy Lifestyle
Interventions: OTHER: The Healthy Living Awareness Program for the Prevention of Osteoporosis (HLAPPO-IMB)- Information stage|OTHER: The Healthy Living Awareness Program for the Prevention of Osteoporosis (HLAPPO-IMB)- Motivation stage|BEHAVIORAL: The Healthy Living Awareness Program for the Prevention of Osteoporosis (HLAPPO-IMB)- Behavior skills stage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effect of the Release of the Tongue Muscles in the Treatment of Chronic Non-specific Neck Pain
Status: UNKNOWN
Conditions: Neck Pain
Interventions: OTHER: Treatment protocol for neck pain|OTHER: Protocol for release of tongue muscles
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Real-time Ultrasound-guided Paramedian Epidural Access: Evaluation of a Novel In-plane Transverse View Technique
Status: COMPLETED
Conditions: Epidural Placement
Interventions: OTHER: epidural needle placement with echogenic 17G Tuohy needles (Pajunk TuohySono)|OTHER: standard epidural placement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Ontario-wide Cancer TArgeted Nucleic Acid Evaluation
Status: RECRUITING
Conditions: Breast Cancer|Lung Cancer|Colorectal Cancer|Melanoma|Gynecological Cancer|Genitourinary Cancer|Pancreatobiliary Cancer|Gastrointestinal Cancer|Head and Neck Cancer|Rare Cancer|Unknown Primary Cancer
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Treatment of Overweight and Obese Children -Using the "Holbaek-Method" in a Municipality Based Treatment Program.
Status: COMPLETED
Conditions: Pediatric Obesity|Dyslipidemia|Hypertension|Diabetes|Quality of Life
Interventions: BEHAVIORAL: Community-based treatment of overweight and obesity
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Caspofungin for the Treatment of Non-blood Candida Infections (0991-045)
Status: COMPLETED
Conditions: Candidiasis
Interventions: DRUG: MK0991, caspofungin acetate/Duration of Treatment: variable
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oxidative Stress in Standard Laparoscopic vs Single Port Cholecystectomy
Status: COMPLETED
Conditions: Uncomplicated Cholelithiasis|Cholecystectomy|Laparoscopy|Standard Technique|Single Port Laparoscopy
Interventions: OTHER: Laparoscopic cholecystectomy|OTHER: Single incision laparoscopic cholecystectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Postoperative Muscular Pain, ETOIMS (Electrical Twitch Obstructive Intramuscular Stimulation)
Status: UNKNOWN
Conditions: Disease Status of Pancreatobiliary Tract , ( Especially Who Need to Undergo Pancreaticoduodenectomy)
Interventions: PROCEDURE: ETOIMS(Electrical Twitch Obtaining Intramuscular Stimulation)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Determining Gastric-Retentive and Modified Release Properties of Prototype Capsules in Healthy Subjects
Status: TERMINATED
Conditions: Gastric Retention|Healthy
Interventions: DRUG: Memantine Hydrochloride MR Prototype Capsule Formulation A|DRUG: Memantine Hydrochloride MR Prototype Capsule Formulation B|DRUG: Memantine Hydrochloride MR Prototype Capsule Formulation C|DRUG: Memantine Hydrochloride MR Prototype Capsule Formulation D|DRUG: Memantine Hydrochloride MR Prototype Capsule Formulation E|PROCEDURE: Magnetic Resonance Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Radioisotope and Fluorescence Guidance in Rectal Cancer
Status: NOT_YET_RECRUITING
Conditions: Rectal Cancer|Lymph Node Metastasis
Interventions: DEVICE: Radiofluorescence
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Effect of Propofol on Renal Injury in Patients Undergoing Valvular Heart Surgery
Status: COMPLETED
Conditions: Heart Valve Disease
Interventions: DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effects of Vitamin E and Vitamin C and Exercise
Status: TERMINATED
Conditions: Exercise and Non-exercise Effect Upon Vitamins E and C
Interventions: DIETARY_SUPPLEMENT: Vitamin E and Vitamin C
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Physical Therapy Trial for Pelvic Pain
Status: COMPLETED
Conditions: Interstitial Cystitis|Painful Bladder Syndrome|Chronic Prostatitis|Chronic Pelvic Pain Syndrome
Interventions: OTHER: Global Therapeutic Massage (GTM)|OTHER: Myofascial physical therapy (MPT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare CAELYX With Topotecan HCL in Patients With Recurrent Epithelial Ovarian Carcinoma Following Failure of First-Line, Platinum-Based Chemotherapy
Status: TERMINATED
Conditions: Epithelial Ovarian Cancer
Interventions: DRUG: CAELYX|DRUG: Topotecan HCl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasound-Guided Transversalis Fascia Plane Block Versus Transmuscular Quadratus Lumborum Block for Post-operative Analgesia in Inguinal Hernia Repair
Status: COMPLETED
Conditions: Pain Management of Inguinal Herniorrhaphy
Interventions: PROCEDURE: QL block|PROCEDURE: TF block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: High (100IU/Kg) Versus Standard (50IU/Kg) Heparin Dose for Prevention of Forearm Artery Occlusion
Status: COMPLETED
Conditions: Coronary Angiography
Interventions: DRUG: High dose of Unfractionated Heparin|DRUG: Standard dose of Unfractionated heparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Plenum® Osshp in Maxillary Sinus Elevation Surgery
Status: RECRUITING
Conditions: Oral Surgical Procedures
Interventions: PROCEDURE: Group 1: Autogenous bone graft|PROCEDURE: Group 2: Plenum® Osshp|PROCEDURE: Group 3: Plenum® Osshp; + i-PRF|PROCEDURE: Group 4: Plenum® Osshp + autogenous bone graft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Exploring Two Strategies of Rivaroxaban (JNJ39039039; BAY-59-7939) and One of Oral Vitamin K Antagonist in Patients With Atrial Fibrillation Who Undergo Percutaneous Coronary Intervention
Status: COMPLETED
Conditions: Atrial Fibrillation|Percutaneous Coronary Intervention
Interventions: DRUG: rivaroxaban 2.5 mg|DRUG: rivaroxaban 15 mg|DRUG: rivaroxaban 10 mg|DRUG: aspirin (ASA)|DRUG: vitamin K antagonist (VKA)|DRUG: clopidogrel|DRUG: prasugrel|DRUG: ticagrelor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Functional Electrical Stimulation for Footdrop in Hemiparesis
Status: COMPLETED
Conditions: Stroke|Hemiplegia
Interventions: DEVICE: Odstock Dropped-Foot Stimulator (ODFS)|OTHER: Conventional Standard of Care|PROCEDURE: Traditional Physical Therapy Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Open-label Study to Assess the Long-term Safety of Difamilast Ointment 1% in Mild to Moderate Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: Difamilast
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose-finding Study of MT-1303 in Subjects With Moderate to Severe Chronic Plaque Psoriasis
Status: COMPLETED
Conditions: Plaque Psoriasis
Interventions: DRUG: MT-1303-Low|DRUG: MT-1303-Middle|DRUG: MT-1303-High|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: VTE Prevention With Rivaroxaban in Genitourinary Cancer Patients Receiving Systemic Therapy
Status: NOT_YET_RECRUITING
Conditions: Venous Thromboembolism|Urologic Cancer
Interventions: DRUG: Rivaroxaban 10 MG|OTHER: Placebo control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison Between Resin Based and Glass Ionomer Based Hydrophilic Fissure Sealants
Status: UNKNOWN
Conditions: Caries
Interventions: PROCEDURE: Sealing deep pits and fissures
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Real-World Practice Patterns and Outcomes of Lower-Risk Myelodysplastic Syndrome Patients in Japan
Status: ACTIVE_NOT_RECRUITING
Conditions: Lower-risk Myelodysplastic Syndromes
Interventions: PROCEDURE: Red blood cell transfusion|PROCEDURE: Red blood cell transfusion
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Prevention of Pain Associated With Rocuronium Injection
Status: COMPLETED
Conditions: Injection Site Irritation
Interventions: DRUG: acetaminophen|DRUG: Lidocaine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized Controlled Trial on Antibiotic Prophylaxis in Children With Vesico-Ureteral Reflux
Status: COMPLETED
Conditions: Pyelonephritis|Renal Scars
Interventions: DRUG: Sulfamethoxazole/trimethoprim
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effects of Cyproterone Compound-spironolactone, Metformin and Pioglitazone on Inflammatory Markers in PCOS
Status: COMPLETED
Conditions: Polycystic Ovary Syndrome
Interventions: DRUG: Cyproterone compound + Spironolactone|DRUG: Metformin|DRUG: Pioglitazone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Use of Antibiotics After Hospital Discharge in Septic Abortion
Status: TERMINATED
Conditions: Abortion, Septic
Interventions: DRUG: placebo|DRUG: doxycycline plus metronidazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nurse Parental Support Using a Mobile App in Symptom Management for CMC
Status: RECRUITING
Conditions: Child With Cancer|Muscular Atrophy|Child With Cerebral Palsy|Child With Medical Complexity
Interventions: OTHER: Nurse parental support in symptom management using a mobile health App
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparing Dual Mini-fragment Plating to Single Precontoured Plating of Acute Midshaft Clavicle Fractures Trial
Status: RECRUITING
Conditions: Clavicle Fracture
Interventions: PROCEDURE: Dual Mini-fragment Plating|PROCEDURE: Single Precontoured Plating
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effective Treatment of Hepatitis C in Substance Users
Status: COMPLETED
Conditions: Hepatitis C|Opiate Dependence
Interventions: PROCEDURE: Modified Directly Observed Therapy (mDOT)|PROCEDURE: Self-Administered Therapy (SAT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Phase I Study to Investigate the Effect on the Blood Pressure After Oral Administration of SK3530 and Amlodipine
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: SK3530 100mg, Placebo, Amlodipine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tolerance of PICC Line Versus Implanted Port for Adjuvant Chemotherapy in Early Breast Cancer
Status: UNKNOWN
Conditions: Early Stage Breast Carcinoma
Interventions: DEVICE: implanted port for chemo administration (X-port isp)|DEVICE: Use of a PICC line for chemo administration (PowerPICC SOLO²)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pain Related Variables
Status: COMPLETED
Conditions: Chronic Neck Pain|Musculoskeletal Pain|Pain Modulation|Cortical Plasticity|Conditioned Pain Modulation|Temporal Summation
Interventions: OTHER: pain related variables assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Patient Satisfaction With Postoperative Follow up After Minimally Invasive Hysterectomy
Status: COMPLETED
Conditions: Minimally Invasive Surgery|Hysterectomy|Postoperative|Satisfaction
Interventions: OTHER: postoperative follow up appointment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Timing of Intradialytic Exercise and Its Impact on Intradialytic Hypotension
Status: COMPLETED
Conditions: Intradialytic Hypotension|Hemodialysis-Induced Symptoms
Interventions: OTHER: Early Intradialytic Exercise|OTHER: Late Intradialytic Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate MILR1444A in the Prevention of Allergen-Induced Airway Obstruction in Adults With Mild Allergic Asthma
Status: COMPLETED
Conditions: Allergic Asthma
Interventions: DRUG: lebrikizumab (MILR1444A)|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Study of an Oral Vitamin D Compound (DP001) in Secondary Hyperparathyroidism in Patients on Hemodialysis
Status: COMPLETED
Conditions: Hyperparathyroidism, Secondary|Kidney Failure, Chronic
Interventions: DRUG: DP001 softgel capsules|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study Evaluating the Elasticity and Shear Wave Modulus (Stiffness) of the Median Nerve in Patients With Mild to Moderate Idiopathic Carpal Tunnel Syndrome Receiving OMT and Conservative Therapy
Status: RECRUITING
Conditions: Carpal Tunnel Syndrome
Interventions: OTHER: Osteopathic manipulative treatment (OMT)|OTHER: Conservative treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multiple Dose Study of MK-3614 (MK-3614-002)
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: MK-3614|DRUG: Placebo for MK-3614
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity of GSK Biologicals' Pandemic Influenza Vaccine (GSK1562902A) at Different Boosting Vaccination Schedules
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Pandemic influenza vaccine GSK1562902A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy of BACMUNE (MV130) in the Prevention of Disease Due to COVID-19 Infection in Healthcare Personnel
Status: WITHDRAWN
Conditions: Covid19
Interventions: BIOLOGICAL: BACMUNE (MV130)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Defined Green Tea Catechin Extract in Treating Women With Hormone Receptor Negative Stage I-III Breast Cancer
Status: COMPLETED
Conditions: Estrogen Receptor-negative Breast Cancer|Progesterone Receptor-negative Breast Cancer|Stage I Breast Cancer|Stage II Breast Cancer|Stage IIIA Breast Cancer|Stage IIIB Breast Cancer
Interventions: OTHER: placebo|OTHER: quality-of-life assessment|PROCEDURE: questionnaire administration|PROCEDURE: laboratory biomarker analysis|DRUG: defined green tea catechin extract
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: BOLT: Study of the Indigo® Aspiration System When Used in Patients With Deep Vein Thrombosis
Status: RECRUITING
Conditions: Deep Vein Thrombosis|DVT
Interventions: DEVICE: Indigo Aspiration System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Shockwave Treatment of Diabetic Foot Ulcer: Step I
Status: WITHDRAWN
Conditions: Chronic Diabetic Foot Ulcers
Interventions: PROCEDURE: Extracorporeal Shock Wave|PROCEDURE: Extracorporeal Shock Wave|PROCEDURE: Extracorporeal Shock Wave|PROCEDURE: Extracorporeal Shock Wave
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Erdafitinib in Participants With Metastatic or Locally Advanced Urothelial Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Urothelial Carcinoma
Interventions: DRUG: Erdafitinib|DRUG: Cetrelimab|DRUG: Cisplatin|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Anti-HIV Drugs in Patients Who Have Not Received Previous Anti-HIV Drugs During Different Stages of HIV Infection
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Indinavir sulfate|DRUG: Nelfinavir mesylate|DRUG: Lamivudine|DRUG: Stavudine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: The Safety and Immunogenicity of SARS-CoV-2 mRNA Vaccine (SYS6006) as Heterologous Booster in Participants Aged 18 Years and Older Vaccinated With Inactivated SARS-CoV-2 Vaccine
Status: UNKNOWN
Conditions: SARS-CoV-2|Safety|Immunotoxicity
Interventions: BIOLOGICAL: one dose of the study SARS-CoV-2 mRNA Vaccine (SYS6006)|OTHER: Cellular Immunity|OTHER: Humoral Immunity|OTHER: Safety
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Docetaxel, Oxaliplatin, and Fluorouracil in Treating Patients With Metastatic or Unresectable Stomach Cancer, Gastroesophageal Junction Cancer, or Other Solid Tumor
Status: COMPLETED
Conditions: Gastric Cancer|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: docetaxel|DRUG: fluorouracil|DRUG: oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of LY3361237 in Participants With Systemic Lupus Erythematosus
Status: COMPLETED
Conditions: Lupus Erythematosus, Systemic
Interventions: DRUG: LY3361237|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Trial to Assess the Clinical Efficacy and Safety of MSJ-0011 in Inducing Ovulation in Anovulatory or Oligo-ovulatory Japanese Women
Status: COMPLETED
Conditions: Anovulation|Oligo-ovulation|Hypothalamic-pituitary Dysfunction|Polycystic Ovarian Syndrome
Interventions: DRUG: MSJ-0011|DRUG: urinary hCG (u-hCG)|DRUG: Follitropin alpha
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Seattle Biopsy Protocol Versus Wide-Area Transepithelial Sampling in Patients With Barrett's Esophagus Undergoing Surveillance
Status: RECRUITING
Conditions: Barrett Esophagus|Barretts Esophagus With Dysplasia|Esophageal Adenocarcinoma
Interventions: DIAGNOSTIC_TEST: Seattle protocol|DIAGNOSTIC_TEST: WATS3D brushings
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Monotherapy of an NMDA Enhancer for Schizophrenia
Status: RECRUITING
Conditions: Schizophrenia
Interventions: DRUG: NMDAE|DRUG: Placebo Cap
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SGLT-2 Inhibitor and Myocardial Perfusion, Function and Metabolism in T2 DM Patients at High Cardiovascular Risk
Status: COMPLETED
Conditions: Type2 Diabetes Mellitus
Interventions: DRUG: Empagliflozin|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy Evaluation of Enobosarm Monotherapy in Treatment of AR+/ER+/HER2- Metastatic Breast Cancer
Status: TERMINATED
Conditions: Metastatic Breast Cancer
Interventions: DRUG: Enobosarm|DRUG: Exemestane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SmART-TBI: Supplementation With Amino Acid Rehabilitative Therapy in TBI
Status: RECRUITING
Conditions: Traumatic Brain Injury
Interventions: DIETARY_SUPPLEMENT: Branched Chain Amino Acids|DIETARY_SUPPLEMENT: Branched Chain Amino Acids|DIETARY_SUPPLEMENT: Branched Chain Amino Acids|DIETARY_SUPPLEMENT: Protein Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study Comparing the Efficacy of Transbuccal Paracetamol 125 mg Versus Paracetamol Injection 1g in Slow Infusion IV in Patients With Acute Pain
Status: COMPLETED
Conditions: Acute Pain
Interventions: DRUG: paracetamol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Intravascular Ultrasound Versus Angiography Guided Drug-coated Balloon
Status: RECRUITING
Conditions: Coronary Artery Disease
Interventions: DEVICE: IVUS guidance|DEVICE: Angiography guidance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sympathetic Mapping/ Ablation of Renal Nerves Trial (SMART) HTN-OFF MED Study
Status: UNKNOWN
Conditions: Essential Hypertension|Vascular Diseases|Cardiovascular Diseases
Interventions: PROCEDURE: Renal nerve stimulation, mapping and denervation|PROCEDURE: Sham Procedure: Renal angiography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Dietary Fiber as Prebiotics on Chemotherapy-related Diarrhea in Patients With Gastrointestinal Tumors
Status: WITHDRAWN
Conditions: Chemotherapy-related Diarrhea
Interventions: DIETARY_SUPPLEMENT: Prebiotic Fiber Supplement + loperamide hydrochloride capsule|DIETARY_SUPPLEMENT: Maltodextrin + loperamide hydrochloride capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Studying Genes in Samples From Younger Patients With Relapsed Acute Lymphoblastic Leukemia
Status: COMPLETED
Conditions: B-cell Childhood Acute Lymphoblastic Leukemia|Recurrent Childhood Acute Lymphoblastic Leukemia|Untreated Childhood Acute Lymphoblastic Leukemia
Interventions: OTHER: laboratory biomarker analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Pharmacokinetics of Alpha-1 Proteinase Inhibitor in Subjects With Alpha1-Antitrypsin Deficiency
Status: COMPLETED
Conditions: Emphysema|Alpha 1-antitrypsin Deficiency (AATD)
Interventions: BIOLOGICAL: Prolastin-C, 60 mg/kg|BIOLOGICAL: Prolastin-C, 120 mg/kg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Early Communication Intervention for Toddlers With Hearing Loss
Status: RECRUITING
Conditions: Hearing Loss, Bilateral
Interventions: BEHAVIORAL: Parent-Implemented Communication Intervention (PICT)|OTHER: No Intervention - Business-as-usual control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Group Cognitive Behavioural Therapy for Youth Anxiety and Insomnia
Status: RECRUITING
Conditions: Insomnia|Anxiety
Interventions: BEHAVIORAL: CBT-I|BEHAVIORAL: CBT-A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety of Brimonidine Tartrate Ophthalmic Solution in a Population of Pediatric, Adult, and Geriatric Participants
Status: COMPLETED
Conditions: Hyperemia
Interventions: DRUG: Brimonidine Tartrate|DRUG: Vehicle|DRUG: Sodium Fluorescein|DRUG: Fluorescein Sodium and Benoximate Hydrocholoride Ophthalmic Solution USP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: The BROADEN Study: A Study of Volanesorsen (Formerly IONIS-APOCIIIRx) in Participants With Familial Partial Lipodystrophy
Status: TERMINATED
Conditions: Familial Partial Lipodystrophy
Interventions: DRUG: volanesorsen|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Recurrence Between Mini-SLET and Limbal-Conjunctival Autograft Techniques in Primary Pterygium
Status: RECRUITING
Conditions: Pterygium of Right Eye|Pterygium of Left Eye|Pterygium of Both Eyes|Pterygium
Interventions: PROCEDURE: Pterygium Excision
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Peer Supported Web-based CBT for OEF/OIF Veterans With PTSD and Substance Misuse
Status: COMPLETED
Conditions: Stress Disorders, Post-traumatic|Substance Use Disorders
Interventions: BEHAVIORAL: Peer-Supported Web CBT|BEHAVIORAL: Self-Managed Web CBT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Solriamfetol in Improving Sleep in Patients With Grade II-IV Glioma
Status: SUSPENDED
Conditions: Glioma|Glioblastoma
Interventions: DRUG: Soliramfetol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy of Equine Assisted Therapy on Negative Symptoms in Patients With Schizophrenia
Status: UNKNOWN
Conditions: Animal Assisted Therapy
Interventions: BEHAVIORAL: equine assisted therapy|BEHAVIORAL: activating control phase
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Brown Fat as Therapeutic Strategy for Obesity and Associated Metabolic Diseases Via Functional Food/Nutraceutical Approach - Molecular Mechanisms of Pentacyclic Triterpenes (BRACE)
Status: NOT_YET_RECRUITING
Conditions: Diabetes|Brown Adipose Tissue
Interventions: OTHER: Maslinic Acid|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: An Open-Label, Phase Ib/II Clinical Trial Of Cdk 4/6 Inhibitor, Ribociclib (Lee011), In Combination With Trastuzumab Or T-Dm1 For Advanced/Metastatic Her2-Positive Breast Cancer.
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Ribociclib|DRUG: T-DM1|DRUG: Trastuzumab|DRUG: Fulvestrant
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT