pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Campath-1H + FK506 and Methylprednisolone for GVHD
Status: COMPLETED
Conditions: Breast Cancer|Chronic Myeloproliferative Disorders|Gestational Trophoblastic Tumor|Graft Versus Host Disease|Leukemia|Lymphoma|Multiple Myeloma and Plasma Cell Neoplasm|Myelodysplastic Syndromes|Myelodysplastic/Myeloproliferative Diseases|Neuroblastoma|Ovarian Cancer|Testicular Germ Cell Tumor
Interventions: BIOLOGICAL: alemtuzumab|DRUG: methylprednisolone|DRUG: tacrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Single Oral Dose Dapagliflozin QT Study
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Dapagliflozin|DRUG: Dapagliflozin|DRUG: Moxifloxacin|DRUG: Placebo to match moxifloxacin and dapagliflozin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study on Ceftazidime and Sulbactam Sodium for Injection (2:1) for Treatment of Respiratory and Urinary Tract Infection
Status: SUSPENDED
Conditions: Respiratory Tract Infections|Urinary Tract Infections
Interventions: DRUG: High dose|DRUG: Low dose|DRUG: Cefoperazone and Sulbactam Sodium (CFP/SUB)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Balloon Prophylaxis of Aneurysmal Vasospasm
Status: COMPLETED
Conditions: Aneurysm|Vasospasm
Interventions: PROCEDURE: transluminal ballooning|OTHER: currently existing therapies for the treatment of vasospasm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: An Exploratory Clinical Trial Evaluating the Tolerability and Efficacy of KH906 in Patients With Corneal Neovascularization
Status: UNKNOWN
Conditions: Corneal Neovascularization
Interventions: DRUG: Conbercept eye drop|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A 52-week, Open-label Extension Study Following a 6-week, Double-blind, Placebo- and Active- Controlled Study (R076477-SCH-303) to Evaluate the Safety and Tolerability of Paliperidone ER in Subjects With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Extended Release OROS® Paliperidone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I Safety and Immunogenicity Preventive Vaccine Trial Based on the HIV-1 Tat and V2-deleted Env Proteins (ISS P-002)
Status: TERMINATED
Conditions: HIV Infection
Interventions: BIOLOGICAL: HIV-1 Tat/delta-V2 Env combined vaccine|BIOLOGICAL: HIV-1 delta-V2 Env vaccine|BIOLOGICAL: HIV-1 Tat vaccine 7.5 microg|BIOLOGICAL: HIV-1 Tat vaccine 30 microg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Experimental Autologous Mesenchymal Stem Cell Therapy in Treatment of Chronic Autoimmune Urticaria
Status: COMPLETED
Conditions: Urticaria|Autoimmune Diseases|Immune System Diseases|Skin Diseases
Interventions: BIOLOGICAL: Autologous mesenchymal stem cell
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Acarbose in Longevity
Status: COMPLETED
Conditions: Aging
Interventions: DRUG: Acarbose|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Basic Body Awareness Therapy on Patients With Chronic Neck Pain
Status: COMPLETED
Conditions: Neck Pain|Proprioceptive Disorders|Balance; Distorted
Interventions: OTHER: BBAT|OTHER: CT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study of Gemcitabine and Concurrent Radiation Followed by Adjuvant Hysterectomy in Bulky Stage Ib and IIa Cervical Carcinoma
Status: COMPLETED
Conditions: Uterine Cervical Cancer
Interventions: DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Modulatory Role of Internet MBCT on Extracellular Vesicles and Distress in Cancer Patients - Study Protocol
Status: RECRUITING
Conditions: Cancer
Interventions: BEHAVIORAL: Mindfulness Based Cognitive Therapy (MBCT)|OTHER: Treatment as Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Continuous Infusion of First-Generation 5-HT3 Receptor Antagonists in Combination With Dexamethasone
Status: RECRUITING
Conditions: Pediatric Cancer
Interventions: DRUG: Ondansetron|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Trial of Two Electrosurgical Conizations: Histopathological Analysis of Excision Margins
Status: COMPLETED
Conditions: Cervical Intraepithelial Neoplasia
Interventions: PROCEDURE: SWETZ|PROCEDURE: LLETZ cone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Psychological Predictors in Colorectal Cancer Surgery Recovery
Status: UNKNOWN
Conditions: Colorectal Cancer
Interventions: OTHER: Questionnaires administration|OTHER: Five Facet Mindfulness Questionnaire (FFMQ)|OTHER: Langer Mindfulness Scale (LMS)|OTHER: Cognitive Flexibility Scale (CFS)|OTHER: Life Orientation Test (LOT)|OTHER: Mini Locus of Control test (MLS)|OTHER: Hospital Anxiety and Depression Scale (HADS)|OTHER: Perceived Stress Scale (PSS)|OTHER: Toronto Alexithymia Scale (TAS)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Determine if BHV-7000 is Effective and Safe in Adults With Refractory Focal Onset Epilepsy
Status: RECRUITING
Conditions: Focal Epilepsy
Interventions: DRUG: BHV-7000|DRUG: BHV-7000|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Quality of Recovery in Parturients Consumed Preoperative Carbohydrate Fluid for Elective Cesarean Delivery
Status: COMPLETED
Conditions: Quality of Life|Breastfeeding|Postoperative Pain|Postoperative Nausea
Interventions: DRUG: Carbohydrate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Kinematic Movements Between ACL Deficiency With ACL Reconstruction and Healthy People
Status: NOT_YET_RECRUITING
Conditions: Anterior Cruciate Ligament Injuries|Anterior Cruciate Ligament Reconstruction|Healthy People
Interventions: DEVICE: Mobilie Bi-planar X-ray Imaging system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study Investigating the Effects of Niagen™ in Healthy Adults.
Status: COMPLETED
Conditions: Bioavailability
Interventions: DIETARY_SUPPLEMENT: Niagen™ 100|DIETARY_SUPPLEMENT: Niagen™ 300|DIETARY_SUPPLEMENT: Niagen™ 1000|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Clinical and Functional Outcome of the MobileLink Acetabular Cup System in the Short-, Mid-, and Longterm Follow-up
Status: RECRUITING
Conditions: Osteoarthritis, Hip|Hip Osteoarthritis|Prosthesis Survival|Prosthesis Failure
Interventions: DEVICE: MobileLink
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Fecal Microbiota Transplantation (FMT) in Patients With Advanced Gastric Cancer
Status: RECRUITING
Conditions: Advanced Gastric Cancer
Interventions: PROCEDURE: Fecal Microbiota Transplantation Capsules|PROCEDURE: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of Neoadjuvant PD-1 Antibody (Toripalimab) Plus Chemotherapy for Locally Advanced Thymic Epithelial Tumor
Status: RECRUITING
Conditions: Thymic Epithelial Tumor
Interventions: DRUG: Toripalimab + Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Kieser Resistance Training Plus Kieser Pelvic Floor Training vs. Kieser Resistance Training Plus Traditional Pelvic Floor Exercise on Urinary Incontinence in Prostate Cancer Patients After Radical Prostatectomy
Status: COMPLETED
Conditions: Prostate Cancer|Prostate Ectomy|Pelvic Floor Disorders|Incontinence, Urinary
Interventions: BEHAVIORAL: Resistance training including the Kieser A5 pelvic floor trainer|BEHAVIORAL: Resistance training without pelvic floor biofeedback Kieser A5 pelvic floor trainer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Exploring the Effect of Rumination-Focused Cognitive Behaviour Therapy in Patients With Schizophrenia
Status: COMPLETED
Conditions: Randomized Controlled Trial
Interventions: BEHAVIORAL: Rumination-Focused Cognitive Behaviour Therapy|OTHER: Health Education programme
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Improving Activity and Quality of Life Following Orthopaedic Trauma: The Trauma Collaborative Care Study (TCCS)
Status: COMPLETED
Conditions: Severe Orthopedic Trauma
Interventions: BEHAVIORAL: Trauma Collaborative Care Plus Treatment as Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Pulmonary Vein Isolation Alone in Patients With Persistent Atrial Fibrillation
Status: UNKNOWN
Conditions: Atrial Fibrillation|Catheter Ablation|Recurrence
Interventions: PROCEDURE: PVI|PROCEDURE: PVI plus additional ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Efficacy of CNTX-4975 in Subjects With Painful Intermetatarsal Neuroma (Morton's Neuroma)
Status: COMPLETED
Conditions: Morton's Neuroma
Interventions: DRUG: CNTX-4975
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of LY3316531 in Healthy Participants and in Participants With Psoriasis
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: LY3316531 - IV|DRUG: LY3316531 - SC|DRUG: Placebo - IV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: VAC 072-An Efficacy Study of R21/MM in Different Dose Schedules
Status: COMPLETED
Conditions: Malaria
Interventions: BIOLOGICAL: R21 Matrix-M vaccination|BIOLOGICAL: R21 Matrix-M vaccination and CHMI|BIOLOGICAL: R21 Matrix-M vaccination booster
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Focused Power Ultrasound Mediated Inferior Perirenal Adipose Tissue Modification Therapy for Essential Hypertension (PARADISE-HTN-II)
Status: RECRUITING
Conditions: Hypertension|Blood Pressure|Cardiovascular Diseases
Interventions: DEVICE: focused power ultrasound mediate inferior perirenal adipose tissue modification|DEVICE: sham-control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Durvalumab and Lenvatinib in Participants With Advanced and Recurrent Endometrial Carcinoma
Status: UNKNOWN
Conditions: Endometrial Cancer
Interventions: DRUG: Durvalumab|DRUG: Lenvatinib Oral Product
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of 3HP-2827 in Treatment of Unresectable or Metastatic Solid Tumors With FGFR2 Alterations
Status: RECRUITING
Conditions: Solid Tumors With FGFR2 Alterations, Adult
Interventions: DRUG: 3HP-2827
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vagus Nerve Stimulation: Treatment for Gulf Veterans With Gulf War Illness
Status: COMPLETED
Conditions: Pain|Migraine
Interventions: DEVICE: VNS device|DEVICE: Inactive device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Clinical Trial of NTQ5082 in Healthy Volunteers
Status: NOT_YET_RECRUITING
Conditions: Complement-mediated Hemolytic Diseases
Interventions: DRUG: NTQ5082|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: PARAT PLUS (The Tubridge Plus For The Treatment Of Wide-Necked Intracranial Aneurysms)
Status: RECRUITING
Conditions: Intracranial Aneurysm
Interventions: DEVICE: Microport NeuroTech Tubridge Plus flow-diverter Stent
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anti-mesothelin CAR T Cells for Patients With Recurrent or Metastatic Malignant Tumors
Status: UNKNOWN
Conditions: Mesothelin Positive Tumors
Interventions: BIOLOGICAL: anti-mesothelin CAR T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of JAK Inhibitors in Patients With AA: RWE Study
Status: RECRUITING
Conditions: Alopecia Areata|Janus Kinase Inhibitors
Interventions: DRUG: Tofacitinib|DRUG: Baricitinib|DRUG: Ruxolitinib|DRUG: Upadacitinib|DRUG: Abrocitinib|DRUG: Ritlecitinib
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Osseotite Certain Prevail for the Preservation of Crestal Bone
Status: UNKNOWN
Conditions: Jaw, Edentulous, Partially
Interventions: DEVICE: Osseotite Prevail Implant|DEVICE: Osseotite Non Prevail Implant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cognitive Behavioral Therapy (CBT) for Latinos With Generalized Anxiety Disorder in the General Medical Sector
Status: COMPLETED
Conditions: Generalized Anxiety Disorder
Interventions: BEHAVIORAL: Cognitive behavior based therapy|BEHAVIORAL: Treatment as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Quetiapine Versus Quetiapine Plus Lithium in Bipolar Depression
Status: COMPLETED
Conditions: Acute Bipolar Depression
Interventions: DRUG: Quetiapine fumarate XR|DRUG: Lithium carbonate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: e-Pharmacovigilance II - Surveillance for Safety and Effectiveness - Calling for Earlier Detection of Adverse Reactions
Status: UNKNOWN
Conditions: Diabetes|Depression|Insomnia|Hypertension
Interventions: BEHAVIORAL: Intervention arm - automated call and phone-based pharmacist counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study of LY2605541 and Insulin Lispro Mixture in Healthy Participants
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: LY2605541|DRUG: Insulin Lispro
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation and Development of Falls Prevention and Management in the Community for Older Adults
Status: UNKNOWN
Conditions: Falls Risk|Falls Prevention
Interventions: BEHAVIORAL: No Message Given|BEHAVIORAL: Positive Message Given - Older Adults|BEHAVIORAL: Negative Message Given - Older Adults|BEHAVIORAL: Positive Message Given - Younger Adults|BEHAVIORAL: Negative Message Given - Younger Adults
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Sequential Treatment of Cabozantinib or Cabozantinib With Nivolumab for Advanced Renal Cell Carcinoma (RCC)
Status: RECRUITING
Conditions: RCC|Renal Cell Carcinoma
Interventions: DRUG: Cabozantinib 80 MG|DRUG: Cabozantinib 40Mg Tab|DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Effectiveness In-ear and Behind-ear Vagus Nerve Stimulation
Status: COMPLETED
Conditions: Vagus Nerve Stimulation
Interventions: DEVICE: Transcutaneous Vagus Nerve Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Effects of Sitagliptin on Endothelial Function in Type 2 Diabetes on Background Metformin Therapy
Status: COMPLETED
Conditions: Diabetes|Atherosclerosis
Interventions: DRUG: sitagliptin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Nordic Luveris Study
Status: COMPLETED
Conditions: Infertility|In Vitro Fertilization
Interventions: DRUG: recombinant luteinizing hormone (Luveris)|DRUG: recombinant follicle stimulating hormone (Gonal-f)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long Term Evaluation and Management of Atrial Fibrillation in Pacemaker Patients
Status: NOT_YET_RECRUITING
Conditions: Permanent Pacemaker Implantation
Interventions: DRUG: midazolam with fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Evaluate the Efficacy and Safety of 'NDTx-01' in Patients With ASD or SCD
Status: RECRUITING
Conditions: Autism Spectrum Disorder|Social Communication Disorder
Interventions: DEVICE: NDTx-01|BEHAVIORAL: TAU
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Determine the Safety and Efficacy of Ribociclib in Combination With Hormone Therapy and Hypofractionated Radiotherapy in Breast Cancer, With Positive Hormone Receptors and Negative HER2 Status, in Newly Diagnosed, Not Immediately Operable Elderly Patient (CALHYS)
Status: RECRUITING
Conditions: HER2 Negative Breast Cancer Not Immediately Operated
Interventions: DRUG: Ribociclib Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of 2 Pancreatic Enzymes for Treatment of Exocrine Pancreatic Insufficiency in Cystic Fibrosis.
Status: COMPLETED
Conditions: Exocrine Pancreatic Insufficiency: Cystic Fibrosis
Interventions: DRUG: EUR-1008 25,000 Units|DRUG: Kreon 25,000 Units
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Haemate HS in Patients With Severe Bleeding Undergoing Valve Replacement Due to Aortic Stenosis
Status: WITHDRAWN
Conditions: Blood Loss, Surgical
Interventions: DRUG: Haemate HS|OTHER: NaCl-solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Coenzyme Q10 in Pediatric Hemodialysis Patients
Status: COMPLETED
Conditions: Hemodialysis
Interventions: DIETARY_SUPPLEMENT: Coenzyme Q10|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of PJS-539 for Adult Patients With COVID-19.
Status: COMPLETED
Conditions: Covid19|COVID-19 Pneumonia
Interventions: DRUG: PJS-539 Dose 1|DRUG: PJS-539 Dose 2|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Virtual Reality (VR) -Directed Brain Gut Behavioral Treatment (BGBT) for Inflammatory Bowel Disease (IBD) Inpatients
Status: RECRUITING
Conditions: Inflammatory Bowel Diseases
Interventions: DEVICE: Virtual reality-directed BGBT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: New Non-Hormonal Treatment by Radiofrequency for Vulvo-Vaginal Atrophy
Status: TERMINATED
Conditions: Vulvo-vaginal Atrophy|Genitourinary Syndrome of Menopause
Interventions: DEVICE: Dynamic Quadripolar Radio-Frequency treatment|DRUG: pH-Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Depth of Anesthesia on Postoperative Clinical Outcome in Patients With Supratentorial Tumor
Status: COMPLETED
Conditions: Anesthesia, Brain Tumor, Supratentorial,Outcome
Interventions: OTHER: Bispectral index will be targeted at 50|OTHER: Bispectral index will be targeted at 35
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Safety and Efficacy of Lean Body Weight-based IV Heparin Dosing in Obese/Morbidly Obese Patients
Status: UNKNOWN
Conditions: Obesity|Morbid Obesity|Venous Thromboembolism|Atrial Fibrillation|Angina|Chest Pain
Interventions: DRUG: Lean Body Weight-based heparin dose
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exercise and Prevention of Syncope: EXPOSE
Status: SUSPENDED
Conditions: Syncope
Interventions: BEHAVIORAL: Exercise|DEVICE: Blood volume|PROCEDURE: VO2max test|PROCEDURE: Lower body negative pressure|BEHAVIORAL: Heart Rate|PROCEDURE: Blood Pressure|BEHAVIORAL: Total Peripheral Resistance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Vitamin D for Treatment of Glioblastoma Multiforme
Status: UNKNOWN
Conditions: Glioblastoma Multiforme
Interventions: OTHER: Surgery|RADIATION: Radiotherapy to tumour bed and/or residual tumour|DRUG: Temozolomide|DRUG: Vitamin D3
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: "Air Assisted"Water Injection Colonoscopy in Experienced Endoscopists
Status: UNKNOWN
Conditions: Colon Disease;|Rectal Disease
Interventions: OTHER: Air insufflation|OTHER: Water injection|OTHER: " Air assisted" water injection.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Panitumumab in Combination With Irinotecan Chemotherapy as 2nd-line Therapy in Subjects With mCRC
Status: COMPLETED
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: Panitumumab and CPT-11
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Individualized Transcranial Direct Current Stimulation for Gait Function in Healthy Subjects
Status: TERMINATED
Conditions: Healthy Adults|Healthy Aging
Interventions: DEVICE: Individualized transcranial direct current stimulation|DEVICE: Conventional transcranial direct current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Camrelizumab Combined With Famitinib Malate for Treatment of Recurrent/Metastatic Cervical Cancer
Status: UNKNOWN
Conditions: Cervical Cancer
Interventions: DRUG: camrelizumab； famitinib malate|DRUG: platinum-based chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Growth Hormone Therapy and Bone Quality in Pediatric Osteoporosis
Status: COMPLETED
Conditions: Osteoporosis
Interventions: DIETARY_SUPPLEMENT: Vitamin D + Calcium + Exercise program|DRUG: Vitamin D + Calcium + Exercise program + Humatrope
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Combined Effects Of Diaphragm Strengthening And Accessory Muscles Stretchings In Asthma Patients
Status: RECRUITING
Conditions: Asthma
Interventions: OTHER: Diaphragm strengthening and accessory muscles stretchings|OTHER: Diaphragm strengthening
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Description of Joint Population and Assessment of Impact on Health Status of Orencia in Patients With Rheumatoid Arthritis in France. A Database Analysis Based on SFR's ORA Long-term Cohort Study
Status: WITHDRAWN
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Orencia
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Rectal Indomethacin Versus Rectal Indomethacin and Sublingual Nitrate for PEP Prevention
Status: UNKNOWN
Conditions: Post-ERCP Acute Pancreatitis
Interventions: DRUG: Isosorbide Dinitrate 5 MG|DRUG: Indomethacin 100 MG|DRUG: Sublingual Placebo|DRUG: Rectal placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: QL Block in Laparoscopic Myomectomy
Status: NOT_YET_RECRUITING
Conditions: Postoperative Pain|Fibroid Uterus
Interventions: DRUG: Bupivacain|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Association Between Calretinin and the Function of Ganglion Cells in Hirschsprung Disease
Status: UNKNOWN
Conditions: Hirschsprung Disease|Ganglion|Hirschsprung Disease, Long-Segment|Hypoganglionosis
Interventions: DIAGNOSTIC_TEST: Calretinin staining
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Systematic Care for Informal Caregivers of Dementia Patients: An Efficient Approach?
Status: COMPLETED
Conditions: Dementia, Vascular|Dementia|Alzheimer Disease|Lewy Body Disease
Interventions: BEHAVIORAL: Diagnosis of caregivers' problems|BEHAVIORAL: Professional service: treatment of problems by counseling or practical support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Prolonged Anticoagulation After a First Episod of Idiopathic Proximal Deep Vein Thrombosis (PADIS TVP)
Status: COMPLETED
Conditions: Recurrent Venous Thromboembolism|Idiopathic Deep Vein Thrombosis
Interventions: DRUG: warfarin|DRUG: placebo of warfarin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nonopioid Analgesia After Arthroscopic Meniscus Surgery
Status: COMPLETED
Conditions: Meniscus Disorder|Narcotic Use
Interventions: DRUG: Celecoxib|DRUG: Hydrocodon/Acetaminophen|DRUG: Ketorolac|DRUG: Gabapentin|DRUG: Acetaminophen|DRUG: Diazepam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Complex Decongestive Physiotherapy Applied After Lymphovenous Anastomosis Surgery
Status: RECRUITING
Conditions: Lymphedema|Cancer
Interventions: BEHAVIORAL: Complex Decongestive Physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Where is the Initial Site of Biotransformation of Folates in Humans?
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: 13C5-folic acid or 13C5-6S-5-FormylTHF
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Clinical Study To Investigate The Effectiveness And Safety Of Tanezumab In Treating Pain Associated With Endometriosis
Status: TERMINATED
Conditions: Endometriosis
Interventions: BIOLOGICAL: Tanezumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Study of KHK4083 in Healthy Volunteers and Subjects With Ulcerative Colitis
Status: COMPLETED
Conditions: Healthy Men and Subjects With Ulcerative Colitis
Interventions: DRUG: KHK4083|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Safety, Tolerability and Pharmacokinetics of ASP2205 in Healthy Young Males and Females and Elderly Females and to Evaluate the Effect of Food on the Pharmacokinetics of a Single Dose of of ASP2205
Status: TERMINATED
Conditions: Healthy Subjects|Pharmacokinetics of ASP2205
Interventions: DRUG: ASP2205|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety and Tolerability Study With Multiple Ascending Doses of ORM-12741
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: ORM-12741
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing Mircera and Epoetin Beta for the Treatment of Anemia in Dialysis Patients With Chronic Kidney Disease.
Status: COMPLETED
Conditions: Anemia
Interventions: DRUG: Epoetin beta|DRUG: methoxy polyethylene glycol-epoetin beta [Mircera]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Levodopa/Benserazide Dispersible Tablet on Response Fluctuations in PD Patients With Delayed ON
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: DRUG: Levodopa dispersible|DRUG: Levodopa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low-dose Challenge Model With Enterotoxigenic E Coli
Status: COMPLETED
Conditions: Diarrhea
Interventions: BIOLOGICAL: E coli strain H10407 and buffer|BIOLOGICAL: E coli strain H10407 and buffer|BIOLOGICAL: E coli strain H10407 and buffer|BIOLOGICAL: E coli H10407 and buffer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: HLA-DRB1 and HLA-DQB1 Genotyping for Autoantibody-positive and -Negative Patients With Atrophic Glossitis or Burning Mouth Syndrome
Status: UNKNOWN
Conditions: Atrophic Glossitis, Burning Mouth Syndrome
Interventions: DIETARY_SUPPLEMENT: Supplementation of vitamin B complex, C, B12, folic acid, Iron and Zinic
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Clinical Feasibility & Validation of the Augmented Reality GlenxRose Acquired Brain Injury Rehabilitation Programs
Status: NOT_YET_RECRUITING
Conditions: Acquired Brain Injury|Stroke|Traumatic Brain Injury
Interventions: DEVICE: GlenXRose Augmented Reality Acquired Brian Injury Therapies
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acupuncture of Different Treatment Frequency in Chronic Plantar Fasciitis
Status: RECRUITING
Conditions: Plantar Fasciitis, Chronic
Interventions: PROCEDURE: electroacupuncture(more frequent)|PROCEDURE: electroacupuncture(less frequent)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Benefits Management for People With Psychiatric Disabilities
Status: COMPLETED
Conditions: Dual Diagnosis|Schizophrenia|Bipolar Disorder
Interventions: BEHAVIORAL: Benefits Management|BEHAVIORAL: Illness Management and Recovery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Catheter Plus Marshall Vein Ablation vs. Catheter Ablation Alone in Persistent AF With Heart Failure
Status: RECRUITING
Conditions: Atrial Fibrillation, Persistent|Heart Failure
Interventions: PROCEDURE: Catheter Ablation Combined with Marshall Vein Ethanol Ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Camu-Camu Prebiotic and Immune Checkpoint Inhibition in Patients With Non-small Cell Lung Cancer and Melanoma
Status: RECRUITING
Conditions: NSCLC Stage IV|Melanoma Stage IV|Unresectable Melanoma|Advanced Non-Small Cell Lung Cancer
Interventions: BIOLOGICAL: Camu Camu Capsules (Camu Camu powder encapsulated (500mg each) + ICI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of an Acupuncture Protocol and Use of Taping in the Treatment of Spastic Upper Limb After Stroke
Status: COMPLETED
Conditions: Stroke|Cerebrovascular Stroke
Interventions: PROCEDURE: Acupuncture|OTHER: Functional Taping|OTHER: Acupuncture and Functional Taping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study Assessing the Effect of 3-week Treatment With One of Three Oral Doses of Quinagolide
Status: COMPLETED
Conditions: Ovarian Hyperstimulation Syndrome
Interventions: DRUG: Norprolac|DRUG: Norprolac|DRUG: Norprolac|DRUG: Norprolac
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy of Combining nbUVB to Etanercept in Patients
Status: COMPLETED
Conditions: Psoriasis Vulgaris
Interventions: DRUG: Etanercept|DEVICE: nbUVB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Medication Maintenance Therapy in Community Pharmacy Settings
Status: COMPLETED
Conditions: Opioid-use Disorder
Interventions: DRUG: Buprenorphine / Naloxone Oral Product|DRUG: injectable naltrexone|OTHER: Pharmacy maintenance addiction care
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Cervical Traction and Neural Mobilization in Patients With Cervical Radiculopathy
Status: UNKNOWN
Conditions: Cervical Radiculopathy
Interventions: OTHER: Neural mobilization combined with traction|OTHER: Traction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of PCSK9 Inhibitor AK102 in Patients With Heterozygous Familial Hypercholesterolemia (HeFH)
Status: COMPLETED
Conditions: Heterozygous Familial Hypercholesterolemia
Interventions: DRUG: AK102|DRUG: Placebo|DRUG: Statins and/or Ezetimibe
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of 2% Chlorhexidine Gluconate in 70% Alcohol Compare 10% Povidone Iodine in Blood Culture in Children
Status: COMPLETED
Conditions: Bacteremia
Interventions: DRUG: 2% chlorhexidine gluconate in 70% alcohol|DRUG: 10%povidone iodine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Digoxin for Patients With Non-alcoholic Steatohepatitis (NASH)
Status: WITHDRAWN
Conditions: Nonalcoholic Steatohepatitis
Interventions: DRUG: Digoxin tablet|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Kinetics, Dosimetry & Safety of [18F]F-AraG, a Positron Emission Tomography Imaging Tracer in Healthy Humans
Status: COMPLETED
Conditions: Cancer
Interventions: DRUG: [18F]F-AraG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effect of Intranasal Oxytocin on Pain Sensitivity and Threshold
Status: COMPLETED
Conditions: Healthy
Interventions: PROCEDURE: Intervention 1|BEHAVIORAL: Washout Period|PROCEDURE: Intervention 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: NB-001 in Children and Adolescents With 22q11 Deletion Syndrome
Status: COMPLETED
Conditions: 22q11 Deletion Syndrome
Interventions: DRUG: NB-001|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Micropulse Trans-Scleral Cyclophotocoagulation Laser (MP-TSCPC) for Glaucoma Patients
Status: RECRUITING
Conditions: Glaucoma
Interventions: DEVICE: MicroPulse Transscleral Laser Therapy using revised P3 Delivery Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Skittles(TM) Effective for Treating Hypoglycemia in Children With Type 1 Diabetes
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus|Hypoglycemia
Interventions: DIETARY_SUPPLEMENT: Ingestion of BD glucose tablets (TM)|DIETARY_SUPPLEMENT: Ingestion of Skittles (TM)|DIETARY_SUPPLEMENT: Ingestion of Fruit to Go (TM)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A 12-week Pilates Programme for Low Back Pain: Perceived and Actual Outcomes
Status: NOT_YET_RECRUITING
Conditions: Low Back Pain
Interventions: PROCEDURE: Pilates Group|PROCEDURE: Exercise Group|PROCEDURE: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Methotrexate Versus Prednisolone as First-line Therapy for Pulmonary Sarcoidosis
Status: ACTIVE_NOT_RECRUITING
Conditions: Sarcoidosis, Pulmonary
Interventions: DRUG: Methotrexate|DRUG: Prednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of CAR-GPRC5D in Patients With Relapsed/Refractory Multiple Myeloma or Plasma Cell Leukemia
Status: RECRUITING
Conditions: Relapsed/Refractory Multiple Myeloma|Plasma Cell Leukemia
Interventions: DRUG: CAR-T (CAR-GPRC5D)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Marrow Cellution™ vs. Traditional BMA Harvest Project
Status: RECRUITING
Conditions: Hip Arthropathy|Avascular Necrosis of Bone|Subchondral Cysts
Interventions: DEVICE: Bone Marrow Collection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study to Evaluate the Safety, Tolerability and Pharmacokinetic Characteristics of HLX26 Monoclonal Antibody Injection in Patients With Solid Tumor or Lymphoma
Status: COMPLETED
Conditions: Solid Tumor, Adult|Lymphoma
Interventions: DRUG: HLX26
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 3D Visualization System for Vitreoretinal Diseases in Highly Myopic Eyes
Status: COMPLETED
Conditions: Patients With Highly Myopic Eyes
Interventions: PROCEDURE: pars plana vitrectomy|DEVICE: NGENUITY® 3D Visualization System (Alcon, TX, USA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Proportional Assist Ventilation And Neurally Adjusted Ventilator Assist
Status: UNKNOWN
Conditions: Acute Respiratory Failure
Interventions: DEVICE: PSV mode|DEVICE: PAV mode|DEVICE: NAVA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gene Expression and Biomarker Profiling of Keloid Skin
Status: COMPLETED
Conditions: Keloid|Keloid of Ear Lobe|Healthy Adults
Interventions: PROCEDURE: Biopsy and/or triamcinolone injection|PROCEDURE: Excisional Biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effect of Affective Content on Drug Induced Amnesia of Episodic Memory
Status: COMPLETED
Conditions: Memory Losses|Amnesia-Memory Loss
Interventions: DRUG: Propofol|DRUG: Thiopental Sodium|DRUG: Dexmedetomidine Hydrochloride|DRUG: Midazolam Hydrochloride|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Novel Oncology Therapies in Combination With Adjuvant Chemo in High-risk MSS-CRC
Status: WITHDRAWN
Conditions: Microsatellite-stable Colorectal Cancer
Interventions: DRUG: Standard of Care - mFOLFOX6|DRUG: E1 - mFOLFOX and durvalumab|DRUG: E2 - mFOLFOX6, durvalumab and oleclumab|DRUG: E3 - mFOLFOX6, durvalumab and monalizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transapical Transcatheter Treatment Versus Conventional Surgery in Patients With Native Aortic Valve Stenosis
Status: TERMINATED
Conditions: Aortic Valve Stenosis
Interventions: PROCEDURE: Transapical Aortic Valve Implantation|PROCEDURE: Conventional Aortic Valve Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevention of Osteoporosis in Bone Marrow Transplantation (BMT) Patients
Status: COMPLETED
Conditions: Hematological Malignancies
Interventions: DRUG: Ibandronate|DRUG: Vitamin Supplements
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sensitivity of an Upper Limb Motion Analysis Protocol to Changes in Kinematics and Muscle Activity After Constraint Induced Therapy in Children With Hemiplegia
Status: COMPLETED
Conditions: Unilateral Cerebral Palsy
Interventions: OTHER: Measurement of maximal forces of elbow pronosupination and flexion-extension
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Phase Ib/II Clinical Trial to Evaluate the Safety and Efficacy of HLX208+HLX10 in NSCLC With BRAF V600E Mutation
Status: RECRUITING
Conditions: Non Small Cell Lung Cancer
Interventions: COMBINATION_PRODUCT: HLX208+HLX10
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anatomy-based Fitting in Unexperienced Cochlear Implant Users
Status: RECRUITING
Conditions: Influence of Anatomy Based Frequency Mapping on Speech Outcomes and Hearing Related Measures
Interventions: OTHER: frequency distribution type
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of IBI110 in Combination With Sintilimab and Chemotherapy in Patients With Untreated Extensive-Stage Small Cell Lung Cancer
Status: COMPLETED
Conditions: SCLC
Interventions: DRUG: Carboplatin|DRUG: Cisplatin|DRUG: Etoposide|DRUG: Sintilimab|DRUG: IBI110
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasound-Guided Thyroid Cartilage Plane Block vs Ultrasound-Guided Traditional Superior Laryngeal Nerve Block for Awake Fiberoptic Intubation in Patients With Limited Neck Mobility Undergoing Cervical Spine Fixation
Status: RECRUITING
Conditions: Patient Satisfaction
Interventions: PROCEDURE: US-guided thyroid cartilage plane block (group TCPB)|PROCEDURE: US-guided traditional superior laryngeal nerve block (group traditional SLNB)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT