pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Safety and Immunogenicity Study of Concomitant Versus Non Concomitant Administration of a Diphtheria, Tetanus, Pertussis and Poliomyelitis Vaccine (REPEVAX) and Influenza Vaccine (VAXIGRIP) in Subjects Aged From 60 Years Old
Status: COMPLETED
Conditions: Diphtheria|Tetanus|Pertussis|Poliomyelitis
Interventions: BIOLOGICAL: Concomitant administration|BIOLOGICAL: Separate administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: To Evaluate Effects of AZD1446, Placebo and Donepezil in Patients With Alzheimer's Disease
Status: TERMINATED
Conditions: Alzheimer´s Disease
Interventions: DRUG: AZD1446|DRUG: Donepezil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Safety of Jinshuibao for Patients With Chronic Kidney Disease Due to Glomerulonephritis
Status: UNKNOWN
Conditions: Chronic Kidney Disease Stage 3B|Chronic Kidney Disease stage4|Glomerulonephritis
Interventions: DRUG: Jinshuibao|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Split Scar Study to Assess Cosmetic Outcome From Differing Suture Spacing
Status: UNKNOWN
Conditions: Suture, Complication|Wound|Wound Complication|Wound Dehiscence|Wound of Skin|Surgery|Suture; Complications, Infection or Inflammation
Interventions: OTHER: Suture spacing for wound closure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Identification of Human Biomarkers Predictive of Diabetes Remission in Type 2 Diabetes Patient (BARIAKINES)
Status: RECRUITING
Conditions: Type 2 Diabetes
Interventions: PROCEDURE: blood samples|PROCEDURE: collection of body tissues|PROCEDURE: routine care procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of MK-8527 in Human Immunodeficiency Type 1 Virus (HIV-1) Infected Participants (MK-8527-002)
Status: COMPLETED
Conditions: Human Immunodeficiency Virus|AIDS Virus
Interventions: DRUG: MK-8527
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neurobehavioral Mechanisms of Psilocybin-assisted Treatment for AUD
Status: NOT_YET_RECRUITING
Conditions: Alcohol Use Disorder
Interventions: DRUG: Psilocybin|OTHER: Inactive Placebo|BEHAVIORAL: Supportive therapy sessions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Ultrasound Guided Axillary Nerve Block Compared to Hematoma Block in Patients With Closed Reposition of Distal Forearm Fractures
Status: COMPLETED
Conditions: Distal Radius Fracture|Forearm Fracture
Interventions: PROCEDURE: Axillary plexus nerve block|PROCEDURE: Fracture hematoma block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radiofrequency for the Treatment of Peripheral Vascular Occlusive Disease of the Lower Extremities
Status: WITHDRAWN
Conditions: Peripheral Vascular Disease
Interventions: DEVICE: GRST Peripheral Catheter System
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Efficacy of Epoetin Alfa Versus Placebo for the Treatment of Anemia in Patients With Acquired Immunodeficiency Syndrome (AIDS) Who Are Receiving Zidovudine (AZT) Therapy
Status: COMPLETED
Conditions: Acquired Immunodeficiency Syndrome|Anemia
Interventions: DRUG: epoetin alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Influence of Injection Rate of Intrathecal Mixture of Local Anesthesia on Hypotension in Cesarean Section
Status: COMPLETED
Conditions: Hypotension
Interventions: OTHER: Low speed|OTHER: High speed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Intraarterial Carboplatin + Caelyx vs Intraarterial Carboplatin + Etoposide Phosphate for Progressing Glioblastoma
Status: RECRUITING
Conditions: Glioblastoma Multiforme|Relapse
Interventions: DRUG: IA Carboplatin + IA Caelyx|DRUG: IA Carboplatin + IA Etoposide Phosphate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PSD502 in Subjects With Premature Ejaculation
Status: COMPLETED
Conditions: Premature Ejaculation
Interventions: DRUG: Placebo|DRUG: PSD502
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: JSKN003 Versus Treatment Of Physician'S Choice For HER2-low, Unresectable and/or Metastatic Breast Cancer Subjects
Status: NOT_YET_RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: JSKN003|DRUG: Capecitabine tablets|DRUG: Gemcitabine hydrochloride for injection|DRUG: Vinorelbine tartrate injection|DRUG: Paclitaxel for injection (albumin-bound type)|DRUG: Docetaxel injection|DRUG: Eribulin mesylate injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Impact of Anesthesia on the Absorption of Glycine in Operative Hysteroscopy: a Randomized Controlled Trial
Status: COMPLETED
Conditions: The Absorption of Glycine in Operative Hysteroscopy
Interventions: PROCEDURE: General anesthesia|PROCEDURE: Local anesthesia with sedation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Shock Wave Therapy on Upper Trapezius Trigger Points in Patients With Cervicogenic Headache.
Status: COMPLETED
Conditions: Cervicogenic Headache
Interventions: OTHER: Shock Wave Therapy|OTHER: US, TENS, IR and exercises.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Daily Polyvagal Exercises on Stress in Students of Physical Therapy
Status: RECRUITING
Conditions: Stress|Anxiety
Interventions: BEHAVIORAL: Polyvagal Breathing Exercises|OTHER: No Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Vitamin C Infusion for TReatment in Sepsis and Alcoholic Hepatitis
Status: COMPLETED
Conditions: Alcoholic Hepatitis|Sepsis
Interventions: DRUG: Vitamin C|DRUG: Dextrose 5% in water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Comparing the Safety and Effectiveness of Magnetic Resonance Guided Focused Ultrasound (MRgFUS) and External Beam Radiation (EBRT) for Treatment of Metastatic Bone Tumors and Multiple Myeloma
Status: COMPLETED
Conditions: Bone Cancer|Bone Metastases|Pain
Interventions: DEVICE: Exablate treatment|RADIATION: Radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Mindfulness for Alzheimer Caregivers
Status: TERMINATED
Conditions: Alzheimer Disease|Neurodegenerative Diseases|Dementia
Interventions: BEHAVIORAL: Mindfulness Based Health Care (MBHC) Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Virtual Reality in Reducing Injection Pain and Anxiety During Local Anesthesia in Children
Status: COMPLETED
Conditions: Injection Pain|Local Anesthesia
Interventions: PROCEDURE: Local anesthesia with conventional syringe|DEVICE: Local anesthesia with conventional syringe + VR device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Do Iron Supplements Impact the Gut Microbiome of Women of Reproductive Age?
Status: COMPLETED
Conditions: Iron-deficiency|Microbial Colonization|Anemia
Interventions: DIETARY_SUPPLEMENT: Ferrous Fumarate|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Study of MK-1084 in KRAS Mutant Advanced Solid Tumors (MK-1084-001)
Status: RECRUITING
Conditions: Advanced Solid Tumors
Interventions: DRUG: MK-1084|BIOLOGICAL: Pembrolizumab|DRUG: carboplatin|DRUG: pemetrexed|BIOLOGICAL: cetuximab|DRUG: oxaliplatin|DRUG: leucovorin|DRUG: 5-fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I, Open-Label, Study of Tumor Infiltrating Lymphocytes Engineered With Membrane Bound IL15 Plus Acetazolamide in Adult Patients With Metastatic Melanoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Tumor|Metastatic Melanoma|Melanoma
Interventions: DRUG: OBX-115|DRUG: Acetazolamide|DRUG: Cyclophosphamide|DRUG: Furosemide|DRUG: Mesna|DRUG: Fludarabine Phosphate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Effect of Linaclotide on Abdominal Girth in Participants With Irritable Bowel Syndrome With Constipation (IBS-C)
Status: TERMINATED
Conditions: Irritable Bowel Syndrome Characterized by Constipation
Interventions: DRUG: Linaclotide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Correction of Hypernatremia by Intravenous Hypotonic Solution Compared to Enteral Water
Status: NOT_YET_RECRUITING
Conditions: Hypernatremia
Interventions: DRUG: Hypotonic Solution|DRUG: Water Purified
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TreatMent Of Knee osTeoarthritis wIth chONdroitin Sulfate - the OA MOTION Study
Status: WITHDRAWN
Conditions: Knee Osteoarthritis
Interventions: DRUG: Chondroitin Sulfate Sodium|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Durability of Response and Safety of Nemolizumab for 24 Weeks in Participants With Prurigo Nodularis
Status: COMPLETED
Conditions: Prurigo Nodularis
Interventions: DRUG: Nemolizumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Does Intravenous Tranexamic Acid Reduce Blood Loss During Vaginectomy?
Status: UNKNOWN
Conditions: Pelvic Organ Prolapse
Interventions: DRUG: Tranexamic Acid Injectable Solution|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Nitrite Effects on Cardiac Muscle in CABG
Status: UNKNOWN
Conditions: Coronary Artery Disease|Atherosclerosis|Vascular Diseases|Cardiac Disease|Diabetes Mellitus
Interventions: DRUG: Sodium Nitrite|DRUG: 0.9% Sodium-chloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study to Investigate the Potential of Probiotics in Yogurt
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Bifidobacterium lactis (BB-12)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Low Tie Versus High Tie of the Inferior Mesenteric Vein During Colorectal Cancer Surgery: A Randomized Clinical Trial
Status: UNKNOWN
Conditions: Anastomotic Leak|Anastomotic Leak Large Intestine|Anastomotic Leak Rectum|Colon Cancer|Colon Neoplasm|Rectum Cancer|Rectum Neoplasm|Colorectal Cancer
Interventions: PROCEDURE: Low tie of IMV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Phase 1b Study of Weekly Carfilzomib in Combination With Lenalidomide and Dexamethasone in Subjects With Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Carfilzomib|DRUG: Lenalidomide|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Growth and Adiposity in Newborns: The Influence of Prenatal Docosahexaenoic Acid (DHA) Supplementation
Status: ACTIVE_NOT_RECRUITING
Conditions: Pregnancy; Nutritional Diseases
Interventions: DIETARY_SUPPLEMENT: Docosahexaenoic acid
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Uterine Artery Ligation at Origin in Total Laparscopic Hystrectomy
Status: COMPLETED
Conditions: Uterine Diseases
Interventions: PROCEDURE: TLH with uterine artery ligation at its origin at the beginning of the operation|PROCEDURE: conventional TLH with uterine artery ligation after the cornual pedicles
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Eluxadoline in the Treatment of Irritable Bowel Syndrome With Diarrhea in Patients With Inadequate Control of Symptoms With Prior Loperamide Use
Status: COMPLETED
Conditions: Irritable Bowel Syndrome With Diarrhea
Interventions: DRUG: Eluxadoline|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: IV Keppra in the Emergency Department for Prevention of Early Recurrent Seizures
Status: COMPLETED
Conditions: Tonic-clonic Seizure
Interventions: DRUG: Keppra|DRUG: Fosphenytoin|DRUG: Dilantin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Investigate the Pharmacokinetics Drug Interaction Between Metformin and Rosuvastatin
Status: COMPLETED
Conditions: Hyperlipidemia|Diabetes
Interventions: DRUG: Metformin|DRUG: Rosuvastatin|DRUG: Metformin and Rosuvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose Ranging Study of Magnesium Iron Hydroxycarbonate in Haemodialysis Subjects With Hyperphosphataemia
Status: COMPLETED
Conditions: Chronic Kidney Failure
Interventions: DRUG: Fermagate|DRUG: Sevelamer HCl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RCT of Addition of 3D Posture Corrective Orthosis to A Multimodal Program of Treatment Of Chronic Postural Neck Pain.
Status: UNKNOWN
Conditions: Neck Pain
Interventions: DEVICE: Study or Experimental Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: POST Facilitation for Community Dwelling Older Adults (POST-RCT)
Status: RECRUITING
Conditions: Anxiety|Depression|Post Traumatic Stress Disorder|Satisfaction
Interventions: BEHAVIORAL: POST Facilitation|BEHAVIORAL: Home Safety Evaluation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Combined Program of Supervised Physical Exercise and Nutritional Counseling in Ovarian Cancer Patients on Frontline Maintenance Treatment With PARP Inhibitors
Status: NOT_YET_RECRUITING
Conditions: Ovarian Cancer
Interventions: PROCEDURE: Exercise and dietary recommendations
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to Learn How Different Amounts of the Study Medicine Called PF-07940369 Are Tolerated and Act in the Body in Healthy Adults.
Status: NOT_YET_RECRUITING
Conditions: Healthy
Interventions: DRUG: PF-07940369|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Multicenter, Open-label Extension Study Evaluating the Efficacy and Safety of IBI311 in Subjects With Thyroid Eye Disease
Status: RECRUITING
Conditions: Thyroid Eye Disease, TED
Interventions: DRUG: IBI311
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessing Uniqueness of Inflammatory Bowel Disease Related Microbiome-derived Biomarkers
Status: COMPLETED
Conditions: Irritable Bowel Disease
Interventions: DEVICE: Hygieacare System
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study of ASN003 in Subjects With Advanced Solid Tumors
Status: TERMINATED
Conditions: Neoplasms|Melanoma|Colorectal Neoplasm|Carcinoma, Non-small Cell Lung
Interventions: DRUG: ASN003 ascending doses|DRUG: ASN003 MTD
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Role of Acetylcholine in Blood Flow Regulation in Healthy Adults: Effects of Age and Exercise Training
Status: WITHDRAWN
Conditions: Vasoconstriction|Vasodilation
Interventions: OTHER: Handgrip Exercise Training|DRUG: Acetylcholine|DRUG: Adenosine Triphosphate|DRUG: Atropine|DRUG: Phenylephrine|DRUG: Sodium Nitroprusside
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Exclusive Enteral Nutrition on Disease Process, Nutritional Status and Gastrointestinal Microbiota for Chinese Children With Crohn's Disease
Status: COMPLETED
Conditions: Crohn Disease|Enteral Nutrition|Gastrointestinal Microbiome
Interventions: DIETARY_SUPPLEMENT: Exclusive Enteral Nutrition
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: In-Home Technology for Caregivers of People With Dementia and Mild Cognitive Impairment: Rural Homes
Status: COMPLETED
Conditions: Dementia|Mild Cognitive Impairment|Alzheimer Disease
Interventions: DEVICE: In-Home Technology System|DEVICE: Limited In-Home Technology
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of Hemodynamic Parameters Following Transjugular Intrahepatic Portosystemic Shunt (TIPS)
Status: ACTIVE_NOT_RECRUITING
Conditions: Refractory Ascites
Interventions: PROCEDURE: Study - Transjugular Intrahepatic Portosystemic Shunt (TIPS)|PROCEDURE: Control - Transjugular Intrahepatic Portosystemic Shunt (TIPS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Benefits and Risks of Artificial Light Exposure: Characterisation of Effects on Alertness, Sleep, Cognitive Performance, Mood and Biological Rhythms
Status: RECRUITING
Conditions: Human Sleep and Chronobiology
Interventions: DEVICE: polychromatic light|DEVICE: polychromatic light|DEVICE: red light|DEVICE: red light|DEVICE: green light|DEVICE: green light
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Real-time Comparison of Left Ventricular Strokevolume Measurement by Four Different Methods
Status: COMPLETED
Conditions: Difference in Measured Results Using Four Different Strokevolume Measurements Simultaneously.
Interventions: PROCEDURE: Arterial waveform analysis, esofageal doppler, transthoracal cardiac ultrasound, Cardiac magnetic resonance imaging.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Relative Bioavailability of CE-Iohexol (Captisol-enabled™ Iohexol) Injection and Omnipaque™ Injection
Status: COMPLETED
Conditions: Contrast-induced Nephropathy|Coronary Angiography
Interventions: OTHER: Omnipaque™ (iohexol) Injection|OTHER: CE-Iohexol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of Human Allogeneic Bone-marrow Derived Mesenchymal Stromal Cell Product (StromaForte) in Patients With Musculoskeletal Injuries and/or Degeneration
Status: RECRUITING
Conditions: Musculoskeletal Injury
Interventions: BIOLOGICAL: Human Allogeneic Bone-Marrow (BM) -Derived Mesenchymal Stromal Cells (MSCs) Product (StromaForte)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Post Market TRUST Study
Status: COMPLETED
Conditions: Uterine Fibroids
Interventions: PROCEDURE: Global Fibroid Ablation (GFA)|PROCEDURE: Abdominal or Laparoscopic Myomectomy|PROCEDURE: Uterine Artery Embolization (UAE)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Amifostine in Treating Young Patients With Newly Diagnosed De Novo Myelodysplastic Syndromes
Status: COMPLETED
Conditions: Myelodysplastic Syndromes|Myelodysplastic/Myeloproliferative Neoplasms
Interventions: DRUG: amifostine trihydrate
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Trephination With Platelet Rich Plasma or Placebo in a Primary Meniscal Tear Treatment
Status: COMPLETED
Conditions: Meniscus Lesion
Interventions: BIOLOGICAL: trephination with placebo|BIOLOGICAL: trephination with platelet rich plasma
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of a Psilocybin Analog (CYB003) in Healthy Participants With and Without Major Depressive Disorder
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: CYB003|BEHAVIORAL: Psychotherapy|DRUG: Placebo|BEHAVIORAL: Psychological Support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, Pharmacodynamic and Pharmacokinetics of a Single Rectal Application of 10 mg NRL001 in Elderly Subjects
Status: COMPLETED
Conditions: Fecal Incontinence
Interventions: DRUG: NRL001|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: INO-5401 and INO-9012 Delivered by Electroporation (EP) in Combination With Cemiplimab (REGN2810) in Newly-Diagnosed Glioblastoma (GBM)
Status: ACTIVE_NOT_RECRUITING
Conditions: Glioblastoma
Interventions: BIOLOGICAL: INO-5401|BIOLOGICAL: INO-9012|BIOLOGICAL: Cemiplimab|RADIATION: Radiation Therapy|DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Evaluation of Positive End-expiratory Pressure in Children Undergoing Mechanical Ventilation Using Supraglottic Airway Device
Status: UNKNOWN
Conditions: Positive End Expiratory Pressure
Interventions: OTHER: PEEP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Effect of PPARγ2 Polymorphism and NSAIDs on Acute Alcohol-induced Changes in Serum Estrogens Among Post-menopausal Women
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Ibuprofen Tab 400 MG|DRUG: Placebo tab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Digital Sedation: Virtual Reality Hypnosis During Colonoscopy
Status: TERMINATED
Conditions: Colonoscopy
Interventions: DEVICE: Aqua© 30 on Oncomfort SedakitTM|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Defibrotide as Prevention and Treatment of Respiratory Distress and Cytokine Release Syndrome of Covid 19.
Status: COMPLETED
Conditions: COVID19
Interventions: DRUG: Defibrotide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intra-articular Injections for Knee Osteoarthritis: A Single Blinded Prospective Randomized Trial
Status: WITHDRAWN
Conditions: Symptomatic Osteoarthritis of the Knee
Interventions: DRUG: 40 mg Depo-Medrol in 1 ml, 9 ml of 1% lidocaine|DRUG: Normal Saline 10 ml|DRUG: Air 10 ml
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Take the Fight in Supporting and Empowering Patients With Cancer
Status: TERMINATED
Conditions: Healthy Subject|Malignant Neoplasm
Interventions: OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration|PROCEDURE: Supportive Care
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Combined CXL//UV and PRK or LASIK in Forme Fruste Keratoconus or Eyes With Potential Risk of Ectasia
Status: COMPLETED
Conditions: Fruste Keratoconus|Risk of Ectasia
Interventions: DEVICE: Corneal Cross-Linking|DRUG: Riboflavin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Natural Cycle or Stimulated Cycle Versus Hormone Replaced Cycle for Pre-eclampsia Rate
Status: UNKNOWN
Conditions: Pre-Eclampsia
Interventions: OTHER: natural cycle for endometrium preparation|OTHER: hormone replaced cycle for endometrium preparation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability of Krill Powder Supplement in Slightly Overweight People With Moderately Elevated Blood Pressure
Status: COMPLETED
Conditions: Adverse Drug Event|Side Effects of Drugs
Interventions: DIETARY_SUPPLEMENT: Nutritional counseling A|DIETARY_SUPPLEMENT: Nutritional counselling B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Usage and Health Effects of Embodied Conversational Agents Among Older Adults
Status: COMPLETED
Conditions: Eating Behavior|Loneliness|Technology Use
Interventions: BEHAVIORAL: PACO|BEHAVIORAL: Waiting list + PACO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Fall Risk Identification and Management for Older Veterans
Status: NOT_YET_RECRUITING
Conditions: Fall Risk
Interventions: OTHER: Strengthening (Physical Therapy, Gerofit)|OTHER: Cognitive Behavioral Therapy (Clinical Psychology, Occupational Therapy)|OTHER: Medication Reconciliation (Clinical Pharmacology)|OTHER: Home Safety Modification (Occupational Therapy)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of GWP42003-P Oral Solution in Children With Epilepsy With Myoclonic-atonic Seizures
Status: TERMINATED
Conditions: Seizures Associated With EMAS
Interventions: DRUG: GWP42003-P|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase IIa Study to Investigate the Efficacy and Safety of AZD7624 in Chronic Obstructive Pulmonary Disease (COPD) Patients While on Maintenance Therapy
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease COPD
Interventions: DRUG: AZD7624 1.0 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Exenatide on 24h-UAER in Patients With Diabetic Nephropathy
Status: COMPLETED
Conditions: Diabetic Nephropathies
Interventions: DRUG: Exenatide|DRUG: Lispro
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Radiation Therapy With or Without Chemotherapy in Treating Patients With High-Risk Endometrial Cancer
Status: COMPLETED
Conditions: Endometrial Cancer
Interventions: DRUG: cisplatin|DRUG: doxorubicin hydrochloride|DRUG: epirubicin hydrochloride|PROCEDURE: adjuvant therapy|PROCEDURE: conventional surgery|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of Autogene Cevumeran With Nivolumab Versus Nivolumab Alone in Participants With High-Risk Muscle-Invasive Urothelial Carcinoma (MIUC)
Status: RECRUITING
Conditions: Muscle Invasive Urothelial Carcinoma
Interventions: DRUG: Autogene Cevumeran|DRUG: Nivolumab|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Liquid Biopsy for High-risk Pre-cancer Screening of Esophageal Adenocarcinoma
Status: COMPLETED
Conditions: Esophagus Cancer|Esophageal Cancer Stage|Esophageal Cancer|Esophageal Neoplasms|Esophagus Adenocarcinoma|Esophagus, Barrett|Barrett Esophagus|Barrett Adenocarcinoma|Barrett Epithelium|Barretts Esophagus With Dysplasia|Barrett's Esophagus Without Dysplasia|Barretts Esophagus With High Grade Dysplasia|Barretts Esophagus With Low Grade Dysplasia|Barrett Esophagus, Long-Segment|Barrett's Esophagus With Dysplasia, Unspecified|Barrett's Esophagus With Esophagitis|Gastroesophageal Reflux|Reflux Disease|Esophageal Adenocarcinoma|Esophageal Dysplasia|Esophageal Neoplasms Malignant
Interventions: DIAGNOSTIC_TEST: EMERALD (Esophageal MicroRNAs for BaRRett's esophagus, Adenocarcinoma, and Dysplasia)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Paracetamol for Catheter Related Bladder Discomfort
Status: COMPLETED
Conditions: Catheter Related Bladder Discomfort
Interventions: DRUG: intravenous paracetamol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Ultrasound-guided Left Stellate Ganglion Block on Rapid Recovery in Patients With Liver Lobectomy and Its Mechanism
Status: RECRUITING
Conditions: Left Stellate Ganglion Block on Rapid Recovery|Possible Molecular Mechanism of Left Stellate Ganglion Block
Interventions: PROCEDURE: Stellate ganglion block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Improvement of Care for Outpatients With Type 2 Diabetes Through Self-Care Multidisciplinary Workshop for Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: BEHAVIORAL: Workshop|BEHAVIORAL: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Levonorgestrel-Releasing Intrauterine System With or Without Everolimus in Treating Patients With Atypical Hyperplasia or Stage IA Grade 1 Endometrial Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Atypical Endometrial Hyperplasia|FIGO Grade 1 Endometrial Endometrioid Adenocarcinoma|FIGO Grade 2 Endometrial Endometrioid Adenocarcinoma
Interventions: DRUG: Everolimus|OTHER: Laboratory Biomarker Analysis|DEVICE: Levonorgestrel-Releasing Intrauterine System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Esophageal capsaïcin Infusion and Mucosal Integrity
Status: COMPLETED
Conditions: TRPV1 Protein, Human|Capsaicin|Electric Impedance|Esophagus|Intracellular Space|Pain Measurement|Microscopy, Electron
Interventions: OTHER: Capsaicin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: ACHRU Community Partnership Program for Diabetes Self-Management for Older Adults - Canada
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Chronic Conditions|Diabetes Mellitus
Interventions: BEHAVIORAL: ACHRU-Community Partnership Program (CPP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study to Compare the Pharmacokinetics Profiles of Four Racecadotril Products
Status: COMPLETED
Conditions: Diarrhea
Interventions: DRUG: Racecadotril|DRUG: Racecadotril|DRUG: Racecadotril|DRUG: Racecadotril
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Depot-medroxy Progesterone Acetate Injectable Contraceptives in Lactating Women 1st Week Versus 6 Week Postpartum Initiation
Status: COMPLETED
Conditions: Complications of DMPA Injectable Contraceptives
Interventions: DEVICE: Depot-medroxy Progesterone Acetate Injectable Contraceptives
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Treating Depression in Coronary Artery Disease With Omega-3 Fatty Acids
Status: COMPLETED
Conditions: Coronary Artery Disease|Depression
Interventions: DIETARY_SUPPLEMENT: Omega-3 Fatty Acid Supplement|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Gemcitabine and Leflunomide in Patients With Advanced Unresectable Pancreatic Cancer
Status: RECRUITING
Conditions: Advanced Pancreatic Adenocarcinoma|Stage III Pancreatic Cancer AJCC v8|Stage IV Pancreatic Cancer AJCC v8|Unresectable Pancreatic Ductal Adenocarcinoma
Interventions: PROCEDURE: Biospecimen Collection|DRUG: Cholestyramine|PROCEDURE: Computed Tomography|PROCEDURE: Diagnostic Imaging|DRUG: Gemcitabine|DRUG: Leflunomide|PROCEDURE: Magnetic Resonance Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Coronary Bifurcation Lesions Treated With Biguard Stent System
Status: WITHDRAWN
Conditions: Coronary Artery Disease
Interventions: DEVICE: Biguard sirolimus-eluting bifurcation stent system|DEVICE: Sirolimus-eluting stent system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Impact of Carbon Monoxide and Altitude on Vascular Function
Status: COMPLETED
Conditions: Vasodilation|Vasoconstriction
Interventions: OTHER: Carbon monoxide rebreathe|DRUG: Sodium Nitroprusside|DRUG: Phenylephrine Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Impact of the Coordinated Intervention of the Healthcare Facilities Pharmacist and the Dispensary Pharmacist on the Care Pathway for Cancer Patients Treated With Oral Therapy
Status: RECRUITING
Conditions: Advanced or Metastatic Solid Tumor|Relapsed Hematologic Malignancy
Interventions: BEHAVIORAL: IPPACTTO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effectiveness of the Geriatric Activation Program Pellenberg (GAPP) on the Geriatric Rehabilitation Ward
Status: COMPLETED
Conditions: Stroke|Hip Fractures|Abdominal Injury|Chronic Obstructive Pulmonary Disease
Interventions: OTHER: Geriatric Activation Program Pellenberg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Ingavirin®, 90 mg Capsules in Patients With COVID-19
Status: COMPLETED
Conditions: COVID-19
Interventions: DRUG: Ingavirin®, 90 mg capsules|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Nicorandil for the Patients of Acute ST Segment Elevation Myocardial Infarction
Status: UNKNOWN
Conditions: Coronary Heart Disease
Interventions: DRUG: Nicorandil|DRUG: normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Randomized Controlled Trial of the Safety and Efficacy of Robotic Telesurgery Versus Laparoscopic Surgery
Status: NOT_YET_RECRUITING
Conditions: Liver Cancer|Renal Cancer|Rectal Cancer
Interventions: PROCEDURE: Robotic telesurgery|PROCEDURE: Laparoscopic surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Contezolid Acefosamil Versus Linezolid for the Treatment of Acute Bacterial Skin and Skin Structure Infection
Status: COMPLETED
Conditions: Skin Diseases, Bacterial|Gram-Positive Bacterial Infections
Interventions: DRUG: contezolid acefosamil|DRUG: linezolid 600 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Real-time Angiographic Co-registered OCT on PCI Results - the OPTICO-integration II Study
Status: COMPLETED
Conditions: Ischaemic Heart Disease
Interventions: PROCEDURE: Angio-PCI|PROCEDURE: OCT-PCI|PROCEDURE: ACR-PCI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Paricalcitol and Chemotherapy in Treating Women With Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: docetaxel|DRUG: ixabepilone|DRUG: paclitaxel|DRUG: paclitaxel albumin-stabilized nanoparticle formulation|DRUG: paricalcitol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Intensive Physical Exercise on Fatigue and Quality of Life in Patients With Quiescent Inflammatory Bowel Disease
Status: RECRUITING
Conditions: Inflammatory Bowel Diseases
Interventions: BEHAVIORAL: Exercise intervention|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RESISTance Exercise for Depression Trial
Status: RECRUITING
Conditions: Major Depressive Disorder
Interventions: BEHAVIORAL: High Dose Resistance Exercise Training|BEHAVIORAL: Low Dose Resistance Exercise Training Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Glucocorticoids and Skin Healing in Diabetes (GC-SHealD)
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: AZD4017|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sedation to Electroencephalography With Dexmedetomidine or Chloral Hydrate
Status: COMPLETED
Conditions: Other Conditions of Brain
Interventions: DRUG: Dexmedetomidine|DRUG: Chloral Hydrate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Thermal Energy in the Treatment of Cervicogenic Dizziness
Status: COMPLETED
Conditions: Dizziness|Cervical Pain
Interventions: DEVICE: Helical® patches
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intranasal SB-705498 in Allergic Rhinitis (AR) Patients
Status: COMPLETED
Conditions: Rhinitis
Interventions: DRUG: SB-705498|DRUG: FP|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intratympanic Steroids for Sudden Hearing Loss
Status: UNKNOWN
Conditions: Dexamethasone or Methylprednisolone; Sudden Hearing Loss; Intratympanic Steroid
Interventions: DRUG: Dexamethasone or Methylprednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Long Biliopancreatic Limb RYGB on Weight Loss and Comorbidities
Status: COMPLETED
Conditions: Morbid Obesity
Interventions: PROCEDURE: Roux-en-Y Gastric Bypass
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Asthma Academy: Use of Simulation and Telehealth to Empower Family Caregivers
Status: COMPLETED
Conditions: Caregiver Burnout
Interventions: BEHAVIORAL: Asthma Academy|BEHAVIORAL: Telehealth Visit
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Aortic or Mitral Valve Replacement With the Braile Biomédica® Bovine Pericardium Valvular Bioprosthesis
Status: RECRUITING
Conditions: Aortic Valve Insufficiency|Aortic Valve Regurgitation|Aortic Valve Stenosis|Aortic Valve Incompetence|Mitral Valve Insufficiency|Mitral Valve Regurgitation|Mitral Valve Stenosis|Mitral Valve Incompetence
Interventions: DEVICE: Braile Biomédica® Bovine Pericardium Valvular Bioprosthesis.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Efficacy of Solifenacin With or Without Tamsulosin in Adult Women With Overactive Bladder (OAB)
Status: COMPLETED
Conditions: Overactive Bladder
Interventions: DRUG: Solifenacin|DRUG: Solifenacin plus Tamsulosin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dapagliflozin and Effect on Cardiovascular Events in Acute Heart Failure -Thrombolysis in Myocardial Infarction 68 (DAPA ACT HF-TIMI 68)
Status: RECRUITING
Conditions: Acute Heart Failure|Heart Failure
Interventions: DRUG: Dapagliflozin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Deep Sensory Assisted Rehabilitation on Gait and Balance in Patients With Multiple Sclerosis
Status: ACTIVE_NOT_RECRUITING
Conditions: MS (Multiple Sclerosis)
Interventions: OTHER: Deep sensory assisted rehabilitation|OTHER: classical rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: BN201 SAD MAD Study in Healthy Subjects
Status: COMPLETED
Conditions: Optic Neuritis|Optic; Neuritis, With Demyelination
Interventions: DRUG: Comparison of BN201 treatment with Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: To Evaluate the Safety and Efficacy of IM and IV Administration of Autologous ADMSCs for Treatment of CLI
Status: UNKNOWN
Conditions: Critical Limb Ischemia
Interventions: BIOLOGICAL: Autologous Stromal Vascular Fraction (SVF)|BIOLOGICAL: Autologous Adipose Derieved MSCs|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Laminar Airflow in Severe Asthma for Exacerbation Reduction
Status: COMPLETED
Conditions: Asthma
Interventions: DEVICE: Temperature-Controlled Laminar Airflow Device (Airsonett®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase II Exploratory, Multicentre, Open-label, Non-comparative Study of ZD1839 (Iressa) and Radiotherapy in the Treatment of Patients With Glioblastoma Multiforme
Status: COMPLETED
Conditions: Glioblastoma
Interventions: DRUG: Gefitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT