pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Efficacy of Docosahexaenoic Acid on Tardive Dyskinesia
Status: UNKNOWN
Conditions: Tardive Dyskinesia
Interventions: DIETARY_SUPPLEMENT: Omega-3 fish oil capsules (including DHA)|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility Study to Treat Lung Cancer With the Permanently Implantable LDR CivaSheet®
Status: RECRUITING
Conditions: Lung Cancer|Lung Cancer Stage I|Lung Cancer Stage II
Interventions: DEVICE: CivaSheet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Coginitve and Physical Functions in Geriatric İndividuals
Status: COMPLETED
Conditions: Cognitive Change|Physical Performance|Frailty|Mobility
Interventions: OTHER: Cognitive Function|OTHER: Physical Performance|OTHER: Grip Strength|OTHER: Walking speed|OTHER: Mobility|OTHER: Fraility
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: RESPOND: Improving the Preparedness of Health Systems to Reduce Mental Health and Psychosocial Concerns Resulting From the COVID-19 Pandemic
Status: UNKNOWN
Conditions: Psychological Distress
Interventions: BEHAVIORAL: Stepped-care DWM/PM+|OTHER: Psychological First Aid + usual care (CAU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of the Diode Laser on Bacteremia Associated With Periodontal Flap Surgery: A Clinico-Microbiological Study
Status: UNKNOWN
Conditions: Chronic Periodontitis
Interventions: PROCEDURE: flap surgery with diode laser|PROCEDURE: flap surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Improvement of Mental Health in Adolescents Using E-health Interventions
Status: NOT_YET_RECRUITING
Conditions: Mental Disorder in Adolescence|Depression in Adolescence|Anxiety Disorders
Interventions: OTHER: A smartphone application|OTHER: Pictorial educational leaflets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Different Crystalloid Coload Volumes on the 90% ED of Norepinephrine
Status: COMPLETED
Conditions: Adverse Effect
Interventions: DRUG: Crystalloid - 0 ml/kg|DRUG: Crystalloid - 5 ml/kg|DRUG: Crystalloid - 10 ml/kg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment With Autologous Skeletal Myoblasts
Status: TERMINATED
Conditions: Old Myocardial Infarction
Interventions: PROCEDURE: Intra-lesion injection of autologous skeletal myoblasts|PROCEDURE: Revascularisation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Ozanimod in Relapsing Multiple Sclerosis
Status: COMPLETED
Conditions: Relapsing Multiple Sclerosis
Interventions: DRUG: Ozanimod|DRUG: Ozanimod placebo|DRUG: Interferon beta-1a|DRUG: Interferon beta-1a placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Bioavailability Between 2 BMS-986141 Formulations in Healthy Participants
Status: WITHDRAWN
Conditions: Healthy
Interventions: DRUG: BMS-986141 Form A Tablet|DRUG: BMS-986141 Form B tablet (low dose)|DRUG: BMS-986141 Form B tablet (high dose)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Protocol for the Infusion of Buffy Coat-derived Cryopreserved Platelets in Patients With Severe Thrombocytopenia
Status: TERMINATED
Conditions: Thrombocytopenia|Primary Thrombocytopenia,Unspecified|Thrombocytopenia Chemotherapy Induced
Interventions: BIOLOGICAL: Transfusion of Pooled Platelets Cryopreserved In DMSO
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Open Label-study to Compare the Efficacy of Aflibercept Monotherapy for Polypoidal Choroidal Vasculopathy
Status: COMPLETED
Conditions: Age Related Macular Degeneration|Polypoidal Choroidal Vasculopathy
Interventions: DRUG: Treat and Extend with Aflibercept 2mg|DRUG: Fixed Dosing with Aflibercept 2mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Intradialytic Exercise on Left Ventricular Diastolic Function in Hemodialysis Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Renal Dialysis|Hemodiafiltration|Diastolic Dysfunction|Kidney Failure|Resistance Training|Quality of Life
Interventions: OTHER: Not exercise|OTHER: Exercise during hemodiafiltration session
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Sorafenib and Palliative Radiotherapy in Kidney Cancer That Spreads to the Bone
Status: COMPLETED
Conditions: Renal Cell Carcinoma
Interventions: DRUG: Sorafenib|RADIATION: external beam radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Celecoxib, Recombinant Interferon Alfa-2b, and Rintatolimod in Treating Patients With Colorectal Cancer Metastatic to the Liver
Status: COMPLETED
Conditions: Metastatic Carcinoma in the Liver|Recurrent Colorectal Carcinoma|Stage IV Colorectal Cancer AJCC v7|Stage IVA Colorectal Cancer AJCC v7|Stage IVB Colorectal Cancer AJCC v7
Interventions: DRUG: Celecoxib|OTHER: Laboratory Biomarker Analysis|BIOLOGICAL: Recombinant Interferon Alfa-2b|DRUG: Rintatolimod
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mesenchymal Stem Cells for Treatment of Refractory Acute Graft-versus-host Disease
Status: UNKNOWN
Conditions: Acute Graft-versus-host Disease
Interventions: BIOLOGICAL: Mesenchymal stem cells|BIOLOGICAL: Non-mesenchymal stem cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Healing Effects of Autologous Platelet Rich Plasma on Gastric Ulcer Caused by Endoscopic Submucosal Dissection
Status: COMPLETED
Conditions: Platelet-rich Plasma|Endoscopic Submucosal Dissection
Interventions: DRUG: Platelet rich plasma|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Full Occlusal Rehabilitation for Patients With Severe Tooth Wear Using Indirect Composite Restorations
Status: UNKNOWN
Conditions: Tooth Wear|Dental Restoration Failure|Dental Restoration Wear
Interventions: PROCEDURE: Rehabilitation of severely worn dentitions
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Monoclonal Antibody Therapy in Treating Patients With Residual Disease From Stage III or Stage IV Ovarian Epithelial, Fallopian Tube, or Peritoneal Cancer Following Surgery and Chemotherapy
Status: UNKNOWN
Conditions: Fallopian Tube Cancer|Ovarian Cancer|Primary Peritoneal Cavity Cancer
Interventions: BIOLOGICAL: oregovomab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Peptide Vaccination With PD-L1 and PD-L2 Peptides in Untreated Chronic Lymphatic Leukemia.
Status: COMPLETED
Conditions: Chronic Lymphocytic Leukemia
Interventions: COMBINATION_PRODUCT: PD-L1, PD-L2 peptides with Montanide ISA51
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Enzyme Suppletion in Exocrine Pancreatic Dysfunction
Status: COMPLETED
Conditions: Chronic Pancreatitis|Exocrine Pancreatic Insufficiency
Interventions: DRUG: Panzytrat 25.000 FIP-E units of Lipase
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endostatin in Combination With Chemotherapy for Metastatic Nasopharyngeal Carcinoma
Status: UNKNOWN
Conditions: Effects of Chemotherapy|Stage IVC Nasopharyngeal Carcinoma
Interventions: DRUG: Recombinant Human Endostatin plus gemcitabine and cisplatin|DRUG: Gemcitabine and cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Predictors of Left Ventricular Hypertrophy in Hypertensive Patients in Assiut Governorate
Status: COMPLETED
Conditions: HTN|Hypertrophy, Left Ventricular
Interventions: DEVICE: sphygmomanometer|DEVICE: mobilogragh|DIAGNOSTIC_TEST: ECG|DIAGNOSTIC_TEST: Echocardiography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: High-Intensity Exercise and High-Fiber Diet for Immunotherapy Outcomes in Melanoma Patients: The DUO Trial
Status: RECRUITING
Conditions: Melanoma (Skin)|Skin Cancer|Advanced Melanoma
Interventions: BEHAVIORAL: Exercise Program|BEHAVIORAL: Diet Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pembrolizumab in Combination With BCG After Ablation in Patients With UUTTCC Without Nephroureterectomy
Status: NOT_YET_RECRUITING
Conditions: High Risk Superficial Upper Urinary Tract Transitional Cell Carcinoma|Endoscopic Surgical Procedure|Transitional Epithelial Cells
Interventions: DRUG: MK-3475 and BCG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Functional Outcome in Midshaft Clavicle Fracture, Treated With Superior Versus Anteroinferior Reconstruction Plate
Status: COMPLETED
Conditions: Closed Fracture of Shaft of Clavicle
Interventions: PROCEDURE: Open Reduction Internal Fixation superior plate|PROCEDURE: Open Reduction Internal Fixation anteroinferior plate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Proprioceptive Exercises on Joint Pain and QoL Among Geriatric Patients With Knee Osteoarthritis
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: PROCEDURE: Proprioceptive exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Two-part Pharmacokinetic and Pharmacodynamic Study of LAS190792 in Patients With Asthma and COPD
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)|Asthma
Interventions: DRUG: LAS190792 Dose 1|DRUG: LAS190792 Dose 2|DRUG: LAS190792 Dose 3|DRUG: LAS190792 Dose 4|DRUG: LAS190792 Dose 5|DRUG: LAS190792 Dose 6|DRUG: LAS190792 Dose 1 (Part 2)|DRUG: LAS190792 Dose 2 (Part 2)|DRUG: Tiotropium 18 μg|DRUG: Indacaterol 150 μg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: MidregiOnal Proatrial Natriuretic Peptide to Guide SEcondary Stroke Prevention
Status: RECRUITING
Conditions: Stroke, Ischemic
Interventions: DRUG: Dabigatran|DRUG: Apixaban|DRUG: Edoxaban|DRUG: Aspirin|DRUG: Clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Oxaliplatin and Cetuximab in First-line Treatment of Metastatic Colorectal Cancer (mCRC)
Status: COMPLETED
Conditions: Neoplasm Metastasis|Colorectal Cancer
Interventions: BIOLOGICAL: Cetuximab|DRUG: Oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Rosuvastatin and Atorvastatin in Patients With Acute Coronary Syndrome
Status: COMPLETED
Conditions: Dyslipidemia|Acute Coronary Syndromes
Interventions: DRUG: rosuvastatin|DRUG: placebo|DRUG: rosuvastatin|DRUG: atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Tolerability of Entospletinib in Combination With Systemic Corticosteroids as First-Line Therapy in Adults With Chronic Graft Versus Host Disease (cGVHD)
Status: TERMINATED
Conditions: Chronic Graft Versus Host Disease
Interventions: DRUG: ENTO|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An Efficacy and Safety Study of Epoetin Alfa (PROCRIT) Initiated at 40,000 Units Every Week Versus 80,000 Units Every Two Weeks in Anemic Patients With Cancer Receiving Chemotherapy.
Status: COMPLETED
Conditions: Anemia
Interventions: DRUG: epoetin alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Advantages of 3D Printing in the Management of Acetabular Fractures
Status: COMPLETED
Conditions: Acetabular Fracture
Interventions: PROCEDURE: Fractures of the posterior structures of the acetabulum treated by fixation using the Kocher-Langenbeck approach.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 68Ga-PSMA-11 PET for the Diagnosis of Biochemically Recurrent Prostate Cancer
Status: COMPLETED
Conditions: Biochemically Recurrent Prostate Carcinoma
Interventions: DRUG: Gallium Ga 68-labeled PSMA-11|PROCEDURE: Positron Emission Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparison of Two Types of Shunts in Infants With Single Ventricle Defect Undergoing Staged Reconstruction--Pediatric Heart Network
Status: COMPLETED
Conditions: Heart Defects, Congenital
Interventions: PROCEDURE: Blalock-Taussig pulmonary artery shunt|PROCEDURE: Right ventricular to pulmonary artery shunt
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevalence and Impact of COVID-19 Infection in Pregnant Women, Fetuses and Newborns
Status: COMPLETED
Conditions: Pregnancy
Interventions: DIAGNOSTIC_TEST: identify SARS-CoV-2 infection by serology|BIOLOGICAL: collection of biological samples
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: SYREN Study: A Study of PEGASYS (Peginterferon Alfa-2a (40KD)) Plus Copegus (Ribavirin) in Non-Responder Patients With Chronic Hepatitis C (CHC) Genotype 1.
Status: COMPLETED
Conditions: Hepatitis C, Chronic
Interventions: DRUG: Copegus|DRUG: Copegus|DRUG: peginterferon alfa-2a [Pegasys]|DRUG: peginterferon alfa-2a [Pegasys]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Change of Renal Function and Bone Mineral Density in CHB Patients Switch From TDF to TAF vs. Maintaining TDF
Status: RECRUITING
Conditions: Chronic Hepatitis B
Interventions: DRUG: Tenofovir alafenamide(TAF)|DRUG: Tenofovir disoproxil fumarate(TDF)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Circadian Adjusted LED Light's Effect in People Living in Elderly Housing
Status: COMPLETED
Conditions: Elderly Housing Residents With Frailty or Dementia
Interventions: OTHER: 8 weeks of circadian adjusted LED-based lighting (CALED)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Involvement of the Inositol-trisphosphate Receptor in Invasive or Migratory-type Breast Cancers
Status: UNKNOWN
Conditions: Breast Cancer|Inosine Triphosphatase
Interventions: OTHER: Assess the level of expression of IP3R3 in cancerous tissues and healthy tissues
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Anti-platelet Effect of Berberine in Patients After Percutaneous Coronary Intervention
Status: RECRUITING
Conditions: Coronary Artery Disease|Percutaneous Coronary Intervention
Interventions: DRUG: Berberine|DRUG: Standard treatment|DRUG: Aspirin|DRUG: Clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lidocaine Patch Versus Intravenous Lidocaine in Pain Relief After Laparoscopy
Status: UNKNOWN
Conditions: Infertility
Interventions: DRUG: lidocaine patches|DRUG: IV lidocaine|DRUG: IV saline infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: REDUCE LAP-HF RANDOMIZED TRIAL I
Status: ACTIVE_NOT_RECRUITING
Conditions: Heart Failure
Interventions: DEVICE: Inter-Atrial Shunt Device|OTHER: Intracardiac Echo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of Amantadine to Treat Gait Dysfunction and Freezing in Parkinson's Disease
Status: TERMINATED
Conditions: Parkinson's Disease
Interventions: DRUG: Amantadine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Optimal Timing of Endoscopic Intervention in the Treatment of Chronic Pancreatitis.
Status: UNKNOWN
Conditions: Pancreatitis, Chronic
Interventions: PROCEDURE: time interval between ESWL and ERCP is 12h|PROCEDURE: time interval between ESWL and ERCP is 12-36h|PROCEDURE: time interval between ESWL and ERCP is greater than 36h|DRUG: morphine, buprenorphine, pethidine, tramaldol, metamizole and acetylsalicylacid (Analgesics)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Research on Traditional Chinese Medicine (TCM) Clinical Treatment of the Acute Episode of Bronchial Asthma.
Status: COMPLETED
Conditions: Bronchial Asthma
Interventions: OTHER: warming lung and relieving asthmatic granule and Securing origin and warming lung emplastrum|OTHER: clearing lung and relieving asthmatic granule and securing origin and clearing lung emplastrum|OTHER: securing origin and relieving asthmatic granule and securing origin and nourishing lung emplastrum|DRUG: Theophylline Sustained-release Tablets and budesonide suspension
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Proof of Concept Study to Investigate Etokimab (ANB020) Activity in Adult Participants With Severe Eosinophilic Asthma
Status: COMPLETED
Conditions: Eosinophilic Asthma
Interventions: BIOLOGICAL: Etokimab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Performance of AQUACEL® Extra™ in Venous Leg Ulcers
Status: COMPLETED
Conditions: Leg Ulcer
Interventions: DEVICE: AQUACEL®|DEVICE: AQUACEL® Extra™
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Opioid Effects on Swallowing Comparing Younger and Elderly Volunteers
Status: COMPLETED
Conditions: Pharyngeal Dysfunction|Pharyngeal Swallowing
Interventions: DRUG: Morphine|DRUG: Remifentanil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Root Coverage With Tunneling Technique With Connective Tissue Versus Coronal Advancement Flap Technique.
Status: NOT_YET_RECRUITING
Conditions: Gingival Recession, Localized|Gingival Recession
Interventions: PROCEDURE: Root coverage with tunneling technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Intranasal Vasoconstrictor Medications on Hemodynamic Parameters: A Randomized Double-blind, Placebo-controlled Trial.
Status: COMPLETED
Conditions: Epistaxis|Blood Pressure
Interventions: DRUG: Oxymetazoline 0.05%|DRUG: Phenylephrine 0.25%|DRUG: Lidocaine 1% plus epinephrine 1:100,000|DRUG: Bacteriostatic 0.9% NaCL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of KALOMIN™ Tab. in Patients With Acute Bronchitis
Status: COMPLETED
Conditions: Acute Bronchitis
Interventions: DRUG: KALOMIN™ Tab.|DRUG: Umckamin syrup
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Clinical Benefit of the Hearing Aids Tinnitus Feature.
Status: COMPLETED
Conditions: Hearing Loss, Sensorineural|Tinnitus
Interventions: DEVICE: hearing aid amplification|DEVICE: hearing aid amplification with an added sound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CAR-GPC3 T Cells in Patients With Refractory Hepatocellular Carcinoma
Status: COMPLETED
Conditions: Hepatocellular Carcinoma
Interventions: GENETIC: CAR-GPC3 T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Multicentre Study of the Use of Ketamine in the Treatment of Refractory Chronic Pain in the French CLCC
Status: COMPLETED
Conditions: Cancer|Chronic Pain|Neuropathic Pain|Opioid Use
Interventions: DRUG: Ketamine use in CLCC sites (indication and administration protocol)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety, Tolerability and Pharmacokinetics of Tiotropium in Cystic Fibrosis Patients
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: Tiotropium bromide low|DRUG: Tiotropium bromide medium|DRUG: Tiotropium bromide high|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Evaluation the Effectiveness of Ru-Yi-Jin-Huang Powder for the Radiation-induced Dermatitis.
Status: UNKNOWN
Conditions: Radiation Dermatitis
Interventions: DRUG: Ru-Yi-Jin-Huang Powder
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assess Safety, Tolerability, Pharmacokinetic and Pharmacodynamic Profile of Ruxolitinib With Artemether-lumefantrine
Status: COMPLETED
Conditions: Malaria
Interventions: DRUG: 20 mg/120 mg artemether-lumefantrine (AL) + 20 mg ruxolitinib phosphate (Rux)|OTHER: 20 mg/120 mg artemether-lumefantrine (AL) + Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Safety and Feasibility of MONOFIX on Fascial Closure of Mid-line Wound After Minimally Invasive Colorectal Cancer Surgery
Status: COMPLETED
Conditions: Colon Cancer|Rectal Cancer|Colon Adenocarcinoma|Rectal Adenocarcinoma
Interventions: DEVICE: Monofix
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Comparison of Electrical Pudendal Nerve Stimulation and Transvaginal Electrical Stimulation for Urge Incontinence
Status: COMPLETED
Conditions: Urge Urinary Incontinence
Interventions: DEVICE: Electrical pudendal nerve stimulation|DEVICE: Transvaginal ES
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Functional and Metabolic Effects of Ketone Bodies on Human Atrial Tissue in Patients With and Without Heart Failure
Status: UNKNOWN
Conditions: Heart Failure|Ischemia Reperfusion Injury|Mitochondrial Pathology
Interventions: DIETARY_SUPPLEMENT: 3-hydroxybuturate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Measuring Uniformed Servicemembers' Fitness Scores on Creatine Loading and Exercise
Status: TERMINATED
Conditions: Physical Fitness
Interventions: DIETARY_SUPPLEMENT: Creatine Monohydrate|DIETARY_SUPPLEMENT: Rice Flour
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Radiotherapy by Sonic Hedgehog Pathway Inhibitors in Basal Cell Carcinoma
Status: NOT_YET_RECRUITING
Conditions: Basal Cell Carcinoma|Radiotherapy; Complications
Interventions: RADIATION: Radiotherapy|OTHER: Observation|DRUG: Vismodegib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of JNJ-78278343, a T-Cell-Redirecting Agent Targeting Human Kallikrein 2 (KLK2), for Advanced Prostate Cancer
Status: RECRUITING
Conditions: Prostatic Neoplasms
Interventions: DRUG: JNJ-78278343
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Genetic Predictors of Variability in the Drug-drug Interaction Between Darunavir/Ritonavir and Pravastatin
Status: COMPLETED
Conditions: HIV Infections|Hyperlipidemia
Interventions: DRUG: Pravastatin|DRUG: Darunavir|DRUG: Ritonavir|DRUG: Pravastatin|OTHER: Washout
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Supplementation With Polyphenol-Rich Foods and Atrial Fibrillation After a Cardiac Surgery
Status: TERMINATED
Conditions: Coronary Heart Disease
Interventions: DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: High-anthocyanin rich corn flour
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Oxygen Insuflation and ArterialDesaturation During Tracheal Intubation in Children
Status: COMPLETED
Conditions: Infants|Difficult Airway
Interventions: OTHER: laryngoscopy with oxygen|OTHER: laryngoscopy without oxygen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Oral Citrulline on Protein Metabolism in Patients With Intestinal Failure (Citrugrêle 2)
Status: COMPLETED
Conditions: Intestinal Failure
Interventions: DRUG: Citrulline and placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Multimodal Magnetic Resonance Imaging-based Study of Electroconvulsive Efficacy Prediction in Adolescents With Depression: a Multicenter Prospective Cohort Study
Status: RECRUITING
Conditions: Major Depressive Disorder|Magnetic Resonance Imaging|Electroconvulsive Therapy
Interventions: DEVICE: Modified Electroconvulsive Therapy|DRUG: Conventional pharmacotherapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Combined Therapy for Acne Scars
Status: UNKNOWN
Conditions: Atrophic Acne Scar
Interventions: DEVICE: Nonablative fractional laser (Fraxel re:store, Solta Medical, Bothell, WA) alone|DEVICE: Nonablative fractional laser (Fraxel re:store, Solta Medical, Bothell, WA) alternating with microneedling with radiofrequency (Intracel, Perigee Medical, Redwood City, CA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Crossover Study to Compare the Pharmacokinetics and Bioavailability of a Novel Furosemide Regimen Administered Subcutaneously vs. the Same Dose Administered Intravenously in Subjects With Chronic Heart Failure
Status: COMPLETED
Conditions: Heart Failure
Interventions: DRUG: Fursemide Injection Solution for subcutaneous administration (80 mg)|DRUG: Furosemide Injection, USP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Separately Evaluate the Activity of Talacotuzumab (JNJ-56022473) or Daratumumab in Transfusion-Dependent Participants With Low or Intermediate-1 Risk Myelodysplastic Syndromes (MDS) Who Are Relapsed or Refractory to Erythropoiesis-Stimulating Agent (ESA) Treatment
Status: COMPLETED
Conditions: Myelodysplastic Syndromes
Interventions: DRUG: Talacotuzumab|DRUG: Daratumumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Modified Lumbar Sustained Natural Apophyseal Glide on Postnatal Low Back Pain
Status: NOT_YET_RECRUITING
Conditions: Low Back Pain
Interventions: OTHER: Strengthening and stretching exercises to the back and abdominal muscles|OTHER: Modified Lumbar Sustained Natural Apophyseal Glide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dexamethasone With Ropivacaine for PENG Block in Total Hip Arthroplasty
Status: NOT_YET_RECRUITING
Conditions: Hip Osteoarthritis|Hip Pain Chronic|Hip Arthritis
Interventions: DRUG: Ropivacaine|DRUG: Ropivacaine+Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Salivary Free Cortisol Response to Cosyntropin Stimulation Test in Mitotane Treated Patients
Status: UNKNOWN
Conditions: Adrenal Insufficiency|Adrenal Cancer
Interventions: DIAGNOSTIC_TEST: Cosyntropin stimulation test
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Impact of Vitamin D Therapies on Chronic Kidney Disease
Status: COMPLETED
Conditions: Chronic Kidney Disease (CKD)|End-stage Renal Disease (ESRD)
Interventions: DRUG: Cholecalciferol - CKD|DEVICE: Calcitriol - CKD|DRUG: Cholecalciferol - non-CKD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of a Multicomponent Intervention on Functional Capacity After Hip Fracture
Status: UNKNOWN
Conditions: Hip Fractures|Osteoporosis|Fall|Frailty Syndrome|Rehabilitation
Interventions: OTHER: ActiveFLS intervention|OTHER: Usual care group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Fib Clinic of the Future Using KardiaPro Platform for Chronic Care of Patients With AF After Ablation Procedure
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DEVICE: Kardia Monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Tuvusertib (M1774) in Combination With Cemiplimab in Participants With Non-Squamous NSCLC (DDRiver NSCLC 322)
Status: RECRUITING
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: M1774|DRUG: Cemiplimab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of PREVENTIVE Substrate Ablation of Coronary Chronic Total Occlusion on Implantable cardioVerTer-Defibrillator Interventions
Status: COMPLETED
Conditions: Ventricular Tachycardia|Ischemic Cardiomyopathy
Interventions: PROCEDURE: Catheter ablation of ventricular tachycardia|DRUG: Optimal medical treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neural Mobilization With Intermittent Cervical Traction on Grip Strength, Sleep Quality, and Quality of Life in Cervical Radiculopathy
Status: RECRUITING
Conditions: Cervical Radiculopathy
Interventions: OTHER: Neural Mobilization with Intermittent Cervical Traction|OTHER: Neural Mobilization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Deep Brain Stimulation of the Dentate Nucleus for Motor Rehabilitation After Stroke
Status: NOT_YET_RECRUITING
Conditions: Stroke|Upper Extremity Paresis
Interventions: DEVICE: deep brain stimulation|OTHER: Rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare the Effectiveness and Safety of Fesoterodine and Placebo in an Elderly Population of Patients Who go to the Toilet Very Frequently Due to Overactive Bladder.
Status: COMPLETED
Conditions: Urinary Bladder, Overactive
Interventions: DRUG: Placebo|DRUG: Fesoterodine fumarate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study on the Safety and Efficacy of CAR-T Therapy for the TM4SF1-positive Tumors of Digestive System
Status: NOT_YET_RECRUITING
Conditions: Digestive Tumor
Interventions: BIOLOGICAL: TM4SF1-positive chimeric antigen receptor T-cell therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Disitamab Vedotin, Fruquintinib and Tislelizumab in Second-line Treatment for HER2-positive MGC
Status: RECRUITING
Conditions: HER2-positive Gastric Cancer|Immunotherapy
Interventions: DRUG: Disitamab Vedotin combined with fruquintinib and Tislelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study Between a 4-mg Dose of Fine Granules of Perampanel and a 4-mg Tablet of Perampanel in Healthy Japanese Subjects
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DRUG: Perampanel|DRUG: Perampanel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Respiratory Muscle Training in Patients With Acute Ischemic Stroke
Status: UNKNOWN
Conditions: Stroke, Ischemic
Interventions: DEVICE: Dofin Breathing Strength Builder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 4FM Acceptance Training as the New Form of cPTSD-focused Treatment Based on Existential Analysis
Status: NOT_YET_RECRUITING
Conditions: Trauma
Interventions: BEHAVIORAL: 4FM Acceptance Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Gather Information About the Proper Dosing and Safety of the Oral FXIa Inhibitor BAY 2433334 in Patients Following an Acute Heart Attack
Status: COMPLETED
Conditions: Acute Myocardial Infarction
Interventions: DRUG: BAY2433334|OTHER: BAY2433334 matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Management of Erectile Dysfunction With Placebo Only
Status: COMPLETED
Conditions: Impotence|Erectile Dysfunction
Interventions: OTHER: Induction to efficient treatment|OTHER: Doubt to the efficacy of treatment|OTHER: Induction to ineffective treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pemetrexed-Carboplatin and Gemcitabine-Vinorelbine in Advanced Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Pemetrexed|DRUG: Carboplatin|DRUG: Gemcitabine|DRUG: Vinorelbine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Home-based Respiratory Muscle Training for Minimizing Side Effects in Patients Undergoing Treatment for Breast Cancer
Status: RECRUITING
Conditions: Breast Carcinoma
Interventions: OTHER: Best Practice|OTHER: Medical Device Usage and Evaluation|PROCEDURE: Respiratory Muscle Training|OTHER: Survey Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Diagnosis of Gastric Intestinal Metaplasia With High Definition Endoscopy and Optic Enhancement
Status: UNKNOWN
Conditions: Gastric Intestinal Metaplasia
Interventions: DEVICE: Standard endoscopy|DEVICE: High definition endoscopy with Optic Enhancement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Testing the Addition of an Anti-cancer Drug, Elimusertib (BAY 1895344) ATR Inhibitor, to the Chemotherapy Treatment (Gemcitabine) for Advanced Pancreatic and Ovarian Cancer, and Advanced Solid Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Fallopian Tube Carcinoma|Advanced Malignant Solid Neoplasm|Advanced Ovarian Carcinoma|Advanced Pancreatic Adenocarcinoma|Advanced Primary Peritoneal Carcinoma|Fallopian Tube High Grade Serous Adenocarcinoma|Metastatic Pancreatic Adenocarcinoma|Ovarian High Grade Serous Adenocarcinoma|Platinum-Resistant Fallopian Tube Carcinoma|Platinum-Resistant Ovarian Carcinoma|Platinum-Resistant Primary Peritoneal Carcinoma|Primary Peritoneal High Grade Serous Adenocarcinoma|Stage II Pancreatic Cancer AJCC v8|Stage III Fallopian Tube Cancer AJCC v8|Stage III Ovarian Cancer AJCC v8|Stage III Pancreatic Cancer AJCC v8|Stage III Primary Peritoneal Cancer AJCC v8|Stage IV Fallopian Tube Cancer AJCC v8|Stage IV Ovarian Cancer AJCC v8|Stage IV Pancreatic Cancer AJCC v8|Stage IV Primary Peritoneal Cancer AJCC v8|Unresectable Pancreatic Adenocarcinoma
Interventions: PROCEDURE: Biopsy|PROCEDURE: Biospecimen Collection|PROCEDURE: Diagnostic Imaging|DRUG: Elimusertib|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Role of High-resolution Anorectal Manometry in the Diagnosis of Functional Anorectal Disorders in Patients With Inactive Inflammatory Bowel Disease
Status: UNKNOWN
Conditions: Inflammatory Bowel Diseases
Interventions: DEVICE: Anorectal manometry
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Dose-Response of Salmeterol in Children
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Advair Diskus100/50 µg|DRUG: Flovent Diskus 100 µg|DRUG: Methacholine Chloride|DRUG: Albuterol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Blood Pressure Measurement Methods and Prediction of Intracranial Hemorrhage After Thrombectomy in Stroke
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Stroke|Blood Pressure|Cerebral Hemorrhage
Interventions: DEVICE: Clearsight device (Edwards) around the finger|DEVICE: Intermittent blood pressure measurements with cuff.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Optimizing and Individualizing the Pharmacological Treatment of First-episode Schizophrenic Patients
Status: COMPLETED
Conditions: Schizophrenia|Metabolic Syndrome
Interventions: DRUG: antipsychotic medications|DRUG: adjunctive group|DRUG: metformin and lifestyle intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Supplemental Perioperative Oxygen to Reduce the Incidence of Post-cesarean Wound Infection
Status: COMPLETED
Conditions: Surgical Wound Infection
Interventions: DEVICE: Supplemental oxygen 80% FIO2|PROCEDURE: Use of air (no oxygen during surgery)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparison of Thermometry in Canada for Pediatrics
Status: WITHDRAWN
Conditions: Healthy|Febrile Illness
Interventions: DEVICE: InstaTemp MD|DEVICE: "Welch Allyn", rectal|DEVICE: "Welch Allyn", oral|DEVICE: Covidien, tympanic
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Visualization Versus Neuromonitoring of the External Branch of the Superior Laryngeal Nerve During Thyroidectomy.
Status: COMPLETED
Conditions: Thyroid,|Goiter,
Interventions: DEVICE: Neuromonitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Oral Salmon Calcitonin in Patients With Knee Osteoarthritis
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DRUG: SMC021 Oral Calcitonin|DRUG: SMC021 Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Orthodontic Varnish Microbiology Study
Status: RECRUITING
Conditions: Dental Caries|Dental Plaque|Dental White Spot
Interventions: DEVICE: Extended Contact RMGI (Resin-modified Glass Ionomer) Varnish|DEVICE: 5% Sodium Fluoride Varnish
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Visual Performance of Four Types of Multifocal Intraocular Lenses
Status: TERMINATED
Conditions: Cataract
Interventions: DEVICE: multifocal intraocular lens IOLs
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness Ankle-7 Orthosis VS HAFO Orthosis on Gait in Diplegic CPChildren
Status: TERMINATED
Conditions: Cerebral Palsy
Interventions: DEVICE: Carbon Ankle Seven spring (A7 - Otto Bock, Germany)|DEVICE: Hinged AFO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Benralizumab in Moderate to Very Severe Chronic Obstructive Pulmonary Disease (COPD) With a History of Frequent Exacerbations
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: BIOLOGICAL: Benralizumab|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Store-and-Forward Teledermatology Versus a Face-to-Face Assessment During a Skin Cancer Screening Event
Status: COMPLETED
Conditions: Skin Cancer|Screening|Telemedicine
Interventions: OTHER: In-person dermatology evaluation|OTHER: Store-and-forward teledermatology evaluation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Correlation Tests for Patients With Benign Paroxysmal Positional Vertigo
Status: COMPLETED
Conditions: Positional Vertigo|Reflexes, Vestibo-Ocular|Nystagmus Vestibular
Interventions: DIAGNOSTIC_TEST: The relationship between the vestibulo-ocular reflex (VOR) gains and the slow phase velocity (SPV)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Combination of Fruquintinib, Tislelizumab and Stereotactic Ablative Radiotherapy in Metastatic Colorectal Cancer(RIFLE)
Status: UNKNOWN
Conditions: Metastatic Colorectal Cancer
Interventions: RADIATION: Stereotactic Ablative Radiotherapy (SABR)|DRUG: Fruquintinib|DRUG: Tislelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Changes in NT-proBNP, Safety, and Tolerability in HFpEF Patients With a WHF Event (HFpEF Decompensation) Who Have Been Stabilized and Initiated at the Time of or Within 30 Days Post-decompensation (PARAGLIDE-HF)
Status: COMPLETED
Conditions: Heart Failure With Preserved Ejection Fraction (HFpEF)
Interventions: DRUG: sacubitril/valsartan|DRUG: valsartan|DRUG: sacubitril/valsartan matching placebo|DRUG: valsartan matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Adductor Canal Block in Outpatient Clinic for Pain Control After Knee Arthroplasty
Status: UNKNOWN
Conditions: Acute Pain|Total Knee Arthroplasty
Interventions: PROCEDURE: adductor canal block in outpatient clinic|DRUG: Analgesics, etoricoxibe
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Beetroot Juice as a Potential Ergogenic Aid During Exercise in Hypoxia
Status: COMPLETED
Conditions: Hypoxia
Interventions: DIETARY_SUPPLEMENT: Beetroot shot then placebo shot|DIETARY_SUPPLEMENT: Placebo shot then beetroot shot
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER