pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Assessing the Effect of Cool Roofs on Health Using Smartwatches in Niue
Status: NOT_YET_RECRUITING
Conditions: Heart Rate|All-day Steps|Distance Walked|Active Minutes|Moderate-intensity Activity Minutes|Vigorous-intensity Activity Duration|Sleep Quantity|Time in Sleep Stages|Awake Duration|Sleep Score
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Outpatient Foley Catheter for Induction of Labor in Nulliparous for Prolonged Pregnancy
Status: TERMINATED
Conditions: Induction of Labour|Prolonged Pregnancy
Interventions: DEVICE: Foley catheter|OTHER: expectative
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effectivity and Safety Study of rExenatide-4 in Chinese Type 2 Diabetes Mellitus
Status: UNKNOWN
Conditions: Type2 Diabetes Mellitus
Interventions: BIOLOGICAL: rE-4 5 mcg|BIOLOGICAL: rE-4 10 mcg|BIOLOGICAL: Placebo 5 mcg|BIOLOGICAL: Placebo 10 mcg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: IL1-TRAP, Rilonacept, in Systemic Sclerosis
Status: COMPLETED
Conditions: Scleroderma|Systemic Sclerosis|Diffuse Scleroderma|Diffuse Systemic Sclerosis
Interventions: DRUG: Rilonacept|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Repetitive Transcranial Magnetic Stimulation in Women With Overactive Bladder With Urgency Incontinence
Status: UNKNOWN
Conditions: Overactive Bladder|Urge Incontinence
Interventions: DEVICE: Repetitive Transcranial Magnetic Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Can Cranberry Juice Enhance the Cognition Accuracy and Alleviate Negative Mental Consequences During Multitasking?
Status: RECRUITING
Conditions: Stress Response|Multitasking Behavior|Mental Stress|Physiological Stress|Cognitive Symptom|Motor Activity
Interventions: DIETARY_SUPPLEMENT: 100% Cranberry Juice|DIETARY_SUPPLEMENT: 100% Cranberry Juice + 200 mg L-theanine|DIETARY_SUPPLEMENT: Placebo Juice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Evaluate the Effect of a Probiotic in Acne
Status: COMPLETED
Conditions: Acne|Acne Vulgaris
Interventions: DIETARY_SUPPLEMENT: Probiotic Bths-08|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: iCBT With TMS in Patients With MDD
Status: ACTIVE_NOT_RECRUITING
Conditions: Major Depressive Disorder
Interventions: DEVICE: Transcranial Magnetic Stimulation|BEHAVIORAL: Internet-Based Cognitive Behavioral Therapy|BEHAVIORAL: Psychoeducation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Preoperative Oral Prednisone on the Operative Field During Nasal Polypectomy.
Status: COMPLETED
Conditions: Nasal Polyps
Interventions: DRUG: Oral Prednisone|DRUG: Placebo comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of MC2-25 Cream & Vehicle in Women With Vulvar Lichen Sclerosus (VLS)
Status: RECRUITING
Conditions: Vulvar Lichen Sclerosus
Interventions: DRUG: MC2-25 cream|DRUG: MC2-25 vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Does Sevoflurane Cause Genomic Damage
Status: UNKNOWN
Conditions: Anesthesia; Adverse Effect
Interventions: DRUG: Sevoflurane|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Boosting Reward-based Attention Through VEstibular STimulation
Status: SUSPENDED
Conditions: Brain Lesion of the Right Hemisphere|Unilateral Spatial Neglect for Half of Them
Interventions: PROCEDURE: Non-invasive brain stimulation of the vestibular system through caloric vestibular stimulation.|PROCEDURE: Non-invasive brain stimulation of the vestibular system through caloric vestibular stimulation.|PROCEDURE: Non-invasive brain stimulation of the vestibular system through caloric vestibular stimulation.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety and Effectiveness of Botulinum Toxin in Elderly Patients With Dementia and Muscle Stiffness
Status: COMPLETED
Conditions: Dementia|Paratonia
Interventions: DRUG: Botulinum Toxin|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ganetespib Window of Opportunity Study in Head and Neck Cancers
Status: TERMINATED
Conditions: Stage I Hypopharyngeal Squamous Cell Carcinoma|Stage I Laryngeal Squamous Cell Carcinoma|Stage I Oral Cavity Squamous Cell Carcinoma|Stage I Oropharyngeal Squamous Cell Carcinoma|Stage II Hypopharyngeal Squamous Cell Carcinoma|Stage II Laryngeal Squamous Cell Carcinoma|Stage II Oral Cavity Squamous Cell Carcinoma|Stage II Oropharyngeal Squamous Cell Carcinoma|Stage III Hypopharyngeal Squamous Cell Carcinoma|Stage III Laryngeal Squamous Cell Carcinoma|Stage III Oral Cavity Squamous Cell Carcinoma|Stage III Oropharyngeal Squamous Cell Carcinoma|Stage IVA Hypopharyngeal Squamous Cell Carcinoma|Stage IVA Laryngeal Squamous Cell Carcinoma|Stage IVA Oral Cavity Squamous Cell Carcinoma|Stage IVA Oropharyngeal Squamous Cell Carcinoma
Interventions: DRUG: Ganetespib|PROCEDURE: Therapeutic Conventional Surgery|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Early Total Thyroidectomy in the Course of Graves' Orbitopathy
Status: UNKNOWN
Conditions: Graves' Ophthalmopathy
Interventions: PROCEDURE: Total Thyroidectomy|DRUG: Propylthiouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Secondary Prevention Education After Acute Myocardial Infarction
Status: COMPLETED
Conditions: Myocardial Infarction, Acute|Anxiety|Education|Quality of Life
Interventions: OTHER: Secondary prevention training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of Erythromycin on Occurrence of Leaks From Cervical Esophageal-Gastric Anastomosis After Trans-Hiatal Esophagectomy
Status: UNKNOWN
Conditions: Esophagectomy|Postoperative Complications
Interventions: DRUG: intravenous (IV) administration of erythromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose:
Clinical trial: Fracture Recovery for Returning to Duty (Teriparatide STRONG)
Status: ENROLLING_BY_INVITATION
Conditions: Stress Fracture of Tibia or Fibula
Interventions: DRUG: Teriparatide|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Imaging Treat-to-target Strategy vs Conventional Treat-to-target Strategy in Psoriatic Arthritis
Status: RECRUITING
Conditions: Psoriatic Arthritis
Interventions: OTHER: Imaging informed treat-to-target|OTHER: Conventional treat-to-target
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BE of Torrent's Esomeprazole Mg DR Capsules
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Nexium 40 mg DR Capsules of AstraZeneca LP, USA.|DRUG: Torrent's Esomeprazole Magnesium DR Capsules 40 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pragmatic Approach to CKD Patient Education
Status: RECRUITING
Conditions: Chronic Kidney Disease stage3|Chronic Kidney Disease stage4|Chronic Kidney Disease Stage 5|Patient Engagement
Interventions: OTHER: CKD "What You Need To Know" Workbook System|OTHER: CKD Action Plan|OTHER: CKD Web-based Resource List|OTHER: Food Label reading exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Antibiotic Prophylaxis in Rectal Cancer Surgery: Oral With Intravenous Versus Intravenous Antibiotics.
Status: UNKNOWN
Conditions: Rectal Cancer
Interventions: DRUG: Oral antibiotic|DRUG: Intravenous antibiotic|DRUG: Mechanical Bowel Preparation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of Lazertinib as Consolidation Therapy in Patients With Locally Advanced, Unresectable, EGFR-Mutant Non-Small Cell Lung Cancer (Stage III) Following Chemoradiation Therapy
Status: RECRUITING
Conditions: Non-small Cell Lung Cancer Stage III|EGFR Positive Non-small Cell Lung Cancer|Non-squamous Non-small-cell Lung Cancer
Interventions: DRUG: Lazertinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ixmyelocel-T Treatment of Patients With Osteonecrosis of the Femoral Head
Status: COMPLETED
Conditions: Osteonecrosis
Interventions: BIOLOGICAL: Ixmyelocel-T|OTHER: Standard of Care Only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of FK199B to Compare Efficacy With Zolpidem by Polysomnography in Patients With Insomnia
Status: COMPLETED
Conditions: Sleep Initiation and Maintenance Disorders
Interventions: DRUG: FK199B|DRUG: Zolpidem
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transcutaneous Auricular Vagus Nerve Stimulation to Enhance Motor Learning
Status: TERMINATED
Conditions: Neurological Injury|Motor Disorders|Paresis
Interventions: OTHER: Transcutaneous Vagus Nerve Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Clinical Evaluation of Subcallosal Cingulate Gyrus Deep Brain Stimulation for Treatment-Resistant Depression
Status: UNKNOWN
Conditions: Treatment Resistant Depression|Depressive Disorder
Interventions: DEVICE: Libra Deep Brain Stimulation System
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PLX038 in Primary Central Nervous System Tumors Containing MYC or MYCN Amplifications
Status: RECRUITING
Conditions: Glioma|Medulloblastoma|Ependymoma
Interventions: DRUG: PLX038
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Efficacy of Ombitasvir/ABT-450/Ritonavir With Sofosbuvir With or Without Ribavirin in Adults With Chronic Hepatitis C Virus Infection
Status: COMPLETED
Conditions: Chronic Hepatitis C Virus Infection
Interventions: DRUG: OBV/PTV/r|DRUG: Sofosbuvir|DRUG: Ribavirin (RBV)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Copanlisib, Letrozole, and Palbociclib in Treating Patients With Hormone Receptor Positive HER2 Negative Stage I-IV Breast Cancer
Status: TERMINATED
Conditions: Estrogen Receptor Positive|HER2/Neu Negative|Invasive Breast Carcinoma|Multifocal Breast Carcinoma|Postmenopausal|Progesterone Receptor Positive|Stage I Breast Cancer|Stage IA Breast Cancer|Stage IB Breast Cancer|Stage II Breast Cancer|Stage IIA Breast Cancer|Stage IIB Breast Cancer|Stage III Breast Cancer|Stage IIIA Breast Cancer|Stage IIIB Breast Cancer|Stage IIIC Breast Cancer|Stage IV Breast Cancer
Interventions: PROCEDURE: Biopsy of Breast|DRUG: Copanlisib|OTHER: Laboratory Biomarker Analysis|DRUG: Letrozole|DRUG: Palbociclib|OTHER: Pharmacological Study
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bupropion and Cigarette-Related Cues in Smokers
Status: COMPLETED
Conditions: Smoking|Smoking, Tobacco
Interventions: DRUG: Bupropion|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Milled Versus Printed CAD/CAM Complete Dentures
Status: COMPLETED
Conditions: Denture, Complete|Jaw, Edentulous
Interventions: DEVICE: manufacturing a complete dental prosthesis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparison of the Effects of ORP-101 Versus Placebo in Adult Patients With Irritable Bowel Syndrome With Diarrhea (IBS-D)
Status: COMPLETED
Conditions: Irritable Bowel Syndrome With Diarrhea
Interventions: DRUG: ORP-101|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Biomarker 11-dh-TXB2 in Blood and Urine Samples From Patients With Prostate Cancer and Healthy Volunteers
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: OTHER: high performance liquid chromatography|OTHER: laboratory biomarker analysis|OTHER: mass spectrometry
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Intrauterine Human Chorionic Gonadotrophins (hCG) and Endometrial Treg Cells
Status: COMPLETED
Conditions: Infertility
Interventions: DRUG: human chorionic gonadotrophin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: PBMC as Biomarkers of Diabetic Cardiomyopathy
Status: RECRUITING
Conditions: Type 2 Diabetes|Metabolic Syndrome|Heart Failure With Preserved Ejection Fraction|Heart Failure With Mildly Reduced Ejection Fraction
Interventions: BIOLOGICAL: Blood test|BEHAVIORAL: quality of life Questionnaire|BEHAVIORAL: Diet habits questionnaire
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Sorafenib Tosylate, Combination Chemotherapy, Radiation Therapy, and Surgery in Treating Patients With High-Risk Stage IIB-IV Soft Tissue Sarcoma
Status: COMPLETED
Conditions: Pleomorphic Rhabdomyosarcoma|Stage IIB Adult Soft Tissue Sarcoma AJCC v7|Stage III Adult Soft Tissue Sarcoma AJCC v7|Stage IV Adult Soft Tissue Sarcoma AJCC v7
Interventions: DRUG: Epirubicin Hydrochloride|RADIATION: External Beam Radiation Therapy|DRUG: Ifosfamide|OTHER: Laboratory Biomarker Analysis|DRUG: Sorafenib Tosylate|PROCEDURE: Therapeutic Conventional Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Initial Stay Times and Heat Mitigation Controls for Uncompensable Occupational Heat Stress - Part II
Status: NOT_YET_RECRUITING
Conditions: Core Temperature|Heat Stress, Exertional|Heat Fatigue|Exercise
Interventions: OTHER: Simulated work in the heat
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Contribution of PET (Positron Emission Tomography) Scans for the Preoperative Assessment of Symptomatic Endometriosis Lesions: TEP-ENDORUN
Status: NOT_YET_RECRUITING
Conditions: Endometriosis
Interventions: DRUG: PET scanner with injection of 18 FDG (18F-2-fluoro-2-deoxy-D-glucose) (radiolabel)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Clinical Trial to Compare the PK of the Fixed-dose Combinations and Each Component of Gemigliptin/Dapagliflozin 50/10 mg
Status: UNKNOWN
Conditions: T2DM
Interventions: DRUG: Zemiglo 50mg and Forxiga 10mg|DRUG: Fixed-dose Combinations of Gemigliptin/Dapagliflozin 50/10 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Open Label Pharmacokinetic Study of OZ439 and Piperaquine on Administration of OZ439+TPGS Granules for Oral Suspension Alone or With Either Piperaquine Phosphate Tablets or Granules for Oral Solution in Healthy Volunteers
Status: COMPLETED
Conditions: Malaria
Interventions: DRUG: 1440mg PQP tablets|DRUG: 960mg PQP tablets|DRUG: 800mg OZ439 + TPGS|DRUG: 960mg PQP granules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Patient-Centered NeuroRehabilitation (PCN)
Status: RECRUITING
Conditions: Cognitive Deficit
Interventions: DEVICE: Active tDCS|DEVICE: Sham tDCS|BEHAVIORAL: Cognitively based intervention|DEVICE: Active tACS|DEVICE: Sham tACS|DEVICE: Active tRNS|DEVICE: Sham tRNS
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non-Invasive Positive Pressure Ventilation Management of High Altitude Pulmonary Edema
Status: UNKNOWN
Conditions: High Altitude Pulmonary Edema|Non-Invasive Positive Pressure Ventilation|Hypoxia
Interventions: DEVICE: Non-Invasive Positive Pressure Ventilation|DRUG: Nifedipine|OTHER: supplemental oxygen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phenylbutyrate Plus Azacitidine in Treating Patients With Acute Myeloid Leukemia, Myelodysplasia, Non-Hodgkin's Lymphoma, Multiple Myeloma, Non-small Cell Lung Cancer, or Prostate Cancer
Status: COMPLETED
Conditions: Leukemia|Lung Cancer|Lymphoma|Multiple Myeloma and Plasma Cell Neoplasm|Myelodysplastic Syndromes|Prostate Cancer
Interventions: DRUG: azacitidine|DRUG: sodium phenylbutyrate
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Dosing Study of Hyperbaric Oxygen Therapy (HBOT) on Epigenetic Aging
Status: ACTIVE_NOT_RECRUITING
Conditions: Aging
Interventions: PROCEDURE: Hyperbaric Oxygen Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Non-Interventional Study To Investigate Whether Information Provided To Patients Influences Their Satisfaction With Toviaz Therapy
Status: TERMINATED
Conditions: Urinary Bladder, Overactive
Interventions: OTHER: Toviaz(fesoterodine) plus educational materials|OTHER: Toviaz(fesoterodine) without educational materials
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Comparison of Supraglottic Airway Devices
Status: COMPLETED
Conditions: Airway Management
Interventions: DEVICE: LMA CLASSIC|DEVICE: LMA FASTRACH|DEVICE: LMA SUPREME
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Local Tolerability and Pharmacokinetic Evaluation of Cyclops Dry Powder Hydroxychloroquine Inhalation in Healthy Volunteers
Status: COMPLETED
Conditions: Covid19
Interventions: DRUG: inhaled hydroxychloroquine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ONC201 With a Methionine-Restricted Diet in Patients With Metastatic Triple Negative Breast Cancer
Status: TERMINATED
Conditions: Triple Negative Breast Cancer
Interventions: DRUG: Akt/ERK Inhibitor ONC201|DIETARY_SUPPLEMENT: Methionine-Restricted Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Use of Nomegestrol Acetate/Estradiol in Random Start Rapid Endometrial Preparation
Status: COMPLETED
Conditions: Endometrial Polyp|Endometrial Diseases
Interventions: DRUG: Nomegestrol Acetate/Estradiol 2.5mg/1.5mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Androgenic Alopecia in Males
Status: COMPLETED
Conditions: Androgenetic Alopecia|Hair Loss|Male Pattern Baldness
Interventions: DEVICE: HairMax LaserComb|DEVICE: Control device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid Tumors
Status: RECRUITING
Conditions: Colorectal Carcinoma|Endometrial Carcinoma|Melanoma|Neuroblastoma|Ovarian Carcinoma|Pancreatic Ductal Adenocarcinoma|Recurrent Desmoid Fibromatosis|Recurrent Ewing Sarcoma|Recurrent Hepatoblastoma|Recurrent Hepatocellular Carcinoma|Recurrent Malignant Solid Neoplasm|Recurrent Non-Hodgkin Lymphoma|Recurrent Osteosarcoma|Refractory Desmoid Fibromatosis|Refractory Ewing Sarcoma|Refractory Hepatoblastoma|Refractory Hepatocellular Carcinoma|Refractory Malignant Solid Neoplasm|Refractory Non-Hodgkin Lymphoma|Refractory Osteosarcoma|Solid Pseudopapillary Neoplasm of the Pancreas|Wilms Tumor
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Dual X-ray Absorptiometry|DRUG: Tegavivint|PROCEDURE: X-Ray Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stress-relief Management for Treatment of Late Complications in Type 2 Diabetes
Status: UNKNOWN
Conditions: Albuminuria|Diabetes Mellitus, Type 2|Diabetes Complications
Interventions: BEHAVIORAL: Mindfulness Based Stress Reduction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Patient Education on Healthy Lifestyle Behaviors and Diabetes Self-management in Diabetics
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Myocardial Infarction
Interventions: OTHER: Planned patient education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Reducing Residual Albuminuria in Subjects With Diabetes and Nephropathy With Atrasentan
Status: COMPLETED
Conditions: Chronic Kidney Disease|Diabetic Nephropathy
Interventions: DRUG: Atrasentan low dose group|DRUG: Atrasentan high dose group|DRUG: Atrasentan placebo group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Flapless Laser Corticotomy in Canine Retraction
Status: COMPLETED
Conditions: Dental Malocclusion|Bimaxillary Protrusion
Interventions: OTHER: Flapless laser corticotomy|OTHER: Canine retraction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Selinexor and Doxorubicin in Advanced Soft Tissue Sarcomas
Status: COMPLETED
Conditions: Soft Tissue Sarcoma
Interventions: DRUG: Selinexor|DRUG: Doxorubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Veın Imagıng Devıce And Vırtual Realıty
Status: COMPLETED
Conditions: Pain, Acute|Emotional Distress|Fear|Anxiety State
Interventions: DEVICE: vein viewer|DEVICE: virtual reality|DEVICE: vein viewer and virtual reality
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: GastroIntestinal Panel in Kidney Transplant Patients
Status: NOT_YET_RECRUITING
Conditions: Kidney Transplant; Complications|Diarrhoea;Acute|Diarrhea Infectious
Interventions: DIAGNOSTIC_TEST: FilmArray GI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Combined Scalp and Ear Acupuncture in Patients With Proton Pump Inhibitor- Dependent Gastroesophageal Reflux Disease
Status: COMPLETED
Conditions: Gastroesophageal Reflux Disease (GERD)|Neurology
Interventions: OTHER: Scalp and auricular acupuncture|OTHER: Seed acupressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Arthrocentesis Alone Versus Arthrocentesis With Hyaluronic Acid Injection
Status: NOT_YET_RECRUITING
Conditions: Temporomandibular Joint Dysfunction Syndrome|Arthrocenteses|Hyaluronic Acid
Interventions: PROCEDURE: arthrocentesis alone|PROCEDURE: arthrocentesis with hyaluronic acid injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Research Evaluating Sleep & Trends for Universal Prevention
Status: COMPLETED
Conditions: Insomnia|Alcohol Use, Unspecified|Marijuana Use
Interventions: BEHAVIORAL: Brief Behavioral Therapy for Insomnia (BBTI)|BEHAVIORAL: Brief Alcohol Screening and Intervention for College Students (BASICS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: First-line Esophageal Carcinoma Study With Pembrolizumab Plus Chemo vs. Chemo (MK-3475-590/KEYNOTE-590)
Status: COMPLETED
Conditions: Esophageal Neoplasms
Interventions: BIOLOGICAL: Pembrolizumab|DRUG: Placebo|DRUG: Cisplatin|DRUG: 5-FU
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Adaptive Treatment De-escalation in Favorable Risk HPV-Positive Oropharyngeal Carcinoma
Status: RECRUITING
Conditions: Oropharyngeal Carcinoma|HPV Positive Oropharyngeal Squamous Cell Carcinoma
Interventions: RADIATION: Standard Radiation Treatment|RADIATION: Dose-Deescalated Treatment|DRUG: Cisplatinum
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Evaluation of Brisdelle™ (Formerly Known as Mesafem) Following Single & Repeat Oral Administration in Healthy Postmenopausal Women
Status: COMPLETED
Conditions: Postmenopausal Symptoms
Interventions: DRUG: Brisdelle (paroxetine mesylate)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Pharmacokinetics of Azelaic Acid Foam, 15% in Papulopustular Rosacea
Status: COMPLETED
Conditions: Papulopustular Rosacea
Interventions: DRUG: Azelaic Acid Foam|DRUG: Azelaic Acid Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Vitamin Deficiency in Immigrants, a Treatment Study
Status: COMPLETED
Conditions: Vitamin D Deficiency
Interventions: DRUG: Cholecalciferol high dose at Vitamin D deficiency|DRUG: Cholecalciferol median dose at Vitamin D insufficiency|DRUG: Cholecalciferol low dose at Vitamin D deficiency|DRUG: Cholecalciferol median dose at sufficient Vitamin D level
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reduced Manipulation of the Aorta and Neurobehavioral Outcome Trial
Status: COMPLETED
Conditions: Coronary Disease
Interventions: PROCEDURE: single aorta clamp with retrograde cardioplegia|PROCEDURE: multiple aorta clamps with antegrade cardioplegia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Bevacizumab and Cetuximab in Combination With FOLFOX6 in Patients With Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Colon Cancer
Interventions: DRUG: Bevacizumab|DRUG: Cetuximab|DRUG: 5-fluorouracil|DRUG: Leucovorin|DRUG: Oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Second Line ERIbulin Followed by CApecitabine or the Reverse Sequence in HER2-negative Metastatic Breast Cancer Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Breast Cancer
Interventions: DRUG: Eribulin Mesylate|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anterior Capsulo-labral Reinsertion by Arthroscopic Approach Versus Immobilization
Status: COMPLETED
Conditions: Bankart Lesion
Interventions: PROCEDURE: Bankart repair|PROCEDURE: Immobilization interne rotation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I Study of XH-S002 in Healthy Volunteers
Status: RECRUITING
Conditions: Healthy Adults
Interventions: DRUG: XH-S002 （A）|OTHER: Placebo（B）
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess Safety, Tolerability and Immunogenicity of RSVpreF From Multidose Vials in Healthy Female Adults.
Status: ACTIVE_NOT_RECRUITING
Conditions: Respiratory Syncytial Virus (RSV)
Interventions: BIOLOGICAL: RSVpreF MDV|BIOLOGICAL: RSVpreF SDV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: SU5416 in Treating Patients With Metastatic Kidney Cancer That Has Not Responded to Previous Treatment
Status: TERMINATED
Conditions: Recurrent Renal Cell Cancer|Stage IV Renal Cell Cancer
Interventions: DRUG: semaxanib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of Cohera Sylys Surgical Sealant as an Adjunct to Standard Bowel Anastomosis Closure
Status: COMPLETED
Conditions: Stoma Reversal Procedure
Interventions: DEVICE: Sylys Surgical Sealant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Carbohydrate Loading and Diabetes in Colorectal Surgery
Status: ACTIVE_NOT_RECRUITING
Conditions: Diabetes Mellitus, Type 2|Surgery|Surgery--Complications
Interventions: DIETARY_SUPPLEMENT: Pre-operative carbohydrate drink
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial to Assess the Clinical Benefit of SSR411298 as Adjunctive Treatment for Persistent Cancer Pain
Status: TERMINATED
Conditions: Pain|Breakthrough Cancer Pain
Interventions: DRUG: SSR411298|DRUG: Placebo (for SSR411298)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study Investigating Transcranial Direct Current Stimulation (tDCS) to Enhance Mindfulness Meditation
Status: COMPLETED
Conditions: Healthy
Interventions: DEVICE: tDCS via Chattanooga Ionto Iontophoresis System-Phoresor|DEVICE: Sham tDCS Chattanooga Ionto Iontophoresis System-Phoresor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Nurse-Community Health Worker-Family Partnership Model: Addressing Uptake of COVID-19 Testing and Control Measures
Status: UNKNOWN
Conditions: COVID-19
Interventions: BEHAVIORAL: Nurse-Community-Family Partnership Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of the Pharmacodynamics and Pharmacokinetics of Insulin Aspart and Human Insulin in Elderly People With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: insulin aspart|DRUG: human insulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Bio-equivalency Study of Moxifloxacin Tablets, 400 mg Under Fasting Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Moxifloxacin Tablets 400 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open-Label Safety and PK Study of ER Hydromorphone Tablets in Opioid-Tolerant Pediatric Chronic Pain Patients
Status: TERMINATED
Conditions: Chronic Pain
Interventions: DRUG: Hydromorphone HCl ER Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pacritinib in Relapsed/Refractory Lymphoproliferative Disorders
Status: TERMINATED
Conditions: Lymphoma, T-Cell, Cutaneous|Lymphoma, T-Cell, Peripheral|Chronic Lymphocytic Leukemia|Lymphoproliferative Disorders|Waldenstrom Macroglobulinemia|Lymphoplasmacytic Lymphoma|Mantle Cell Lymphoma
Interventions: DRUG: Pacritinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Red Blood Cells From Umbilical Cord for Transfusion of Preterm Infants
Status: RECRUITING
Conditions: Infant, Extremely Premature|Erythrocyte Transfusion|Umbilical Cord Issue
Interventions: OTHER: Red blood cell from umbilical cord blood|OTHER: Red blood cell from adult donor
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dosing, Safety and Pharmacokinetic Profile of Rifabutin in Children Receiving Concomitant Treatment With Kaletra
Status: UNKNOWN
Conditions: Children With Confirmed HIV Infection|Receiving ART Regimen Containing 2 NRTIs + LPV/RTV at Standard Dose|Successfully Completed TB Treatment in the Past 2 to 6 Weeks of Enrollment
Interventions: DRUG: Mycobutin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Incidence of Melanoma and Non-melanoma Skin Cancer in People With Vitiligo
Status: COMPLETED
Conditions: Vitiligo|Melanoma (Skin)|Nonmelanoma Skin Cancer|Squamous Cell Carcinoma|Basal Cell Carcinoma|Actinic Keratoses
Interventions: OTHER: Exposure of skin cancer of interest
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of cogniVida™ on Learning and Memory and in Comparison to Placebo After Long-term Supplementation
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: cogniVida™ 100 mg/day|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Customized Medication Adherence Enhancement for Treating Adults With Bipolar Disorder
Status: COMPLETED
Conditions: Bipolar Disorder
Interventions: BEHAVIORAL: Psychoeducation module|BEHAVIORAL: Substance abuse module|BEHAVIORAL: Improved communication/rapport with provider module|BEHAVIORAL: Medication routines management module
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase Ⅱ Study of Pegylated Liposomal Doxorubicin（PLD）Plus Trastuzumab in HER-2 Positive Metastatic Breast Cancer
Status: UNKNOWN
Conditions: HER2-positive Breast Cancer
Interventions: DRUG: pegylated liposomal doxorubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Intensive Cognitive Behavioral Therapy in Treating Adolescent Panic Disorder and Agoraphobia
Status: COMPLETED
Conditions: Panic Disorder|Agoraphobia
Interventions: BEHAVIORAL: Intensive panic control treatment without parent involvement|BEHAVIORAL: Intensive panic control treatment with parent involvement|OTHER: Waitlist control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparison of FDG-PET Versus MRI Based Target Volume Delineation in Glioblastoma and the Role of FDG-PET/CT in the Alteration of MRI Based Target Volumes.
Status: UNKNOWN
Conditions: Glioblastoma
Interventions: PROCEDURE: FDG-PET
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Determine the PK and Safety and Tolerability of ATM-AVI for the Treatment of cIAIs in Hospitalized Adults (REJUVENATE)
Status: COMPLETED
Conditions: Complicated Intra-Abdominal Infections, cIAIs
Interventions: DRUG: ATM-AVI|DRUG: Metronidazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CANARY: Coronary Assessment by Near-infrared of Atherosclerotic Rupture-prone Yellow
Status: TERMINATED
Conditions: Coronary Atherosclerosis|Myocardial Infarction|Coronary Plaque Embolization
Interventions: DEVICE: Embolic Protection Device (EPD)|DEVICE: Intracoronary Spectroscopy and Ultrasonic Evaluation|DEVICE: Angioplasty and Stent Implant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fortified Rice for School Children in Cambodia
Status: COMPLETED
Conditions: Micronutrient Status
Interventions: DIETARY_SUPPLEMENT: Fortified rice cold extruded kernel|DIETARY_SUPPLEMENT: fortified rice warm extruded kernel|DIETARY_SUPPLEMENT: fortiified rice hot extruded kernel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Uremic Toxin Removal and Hemodynamics in Long-hour Hemodialysis and Hemodiafiltration
Status: COMPLETED
Conditions: Uremic Toxins|Haemodynamic Stability
Interventions: OTHER: 4-hour HD, 4-hour HDF, 8-hour HD and 8-hour HDF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An MRI Ancillary Study of a Malaria Fever Investigation
Status: COMPLETED
Conditions: Brain Injuries|Malaria|MRI Imaging|Neurocognitive Deficits|Chronic Kidney Diseases|Behavior Problem
Interventions: OTHER: Aggressive antipyretics therapy of fever vs usual care in the Malaria RCT study
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: CD79b-19 CAR T Cells in Non-Hodgkin Lymphoma
Status: RECRUITING
Conditions: Non-hodgkin Lymphoma|Relapsed Non-Hodgkin Lymphoma|Refractory Non-Hodgkin Lymphoma|Follicular Lymphoma|Marginal Zone Lymphoma|Diffuse Large B Cell Lymphoma|Primary Mediastinal Large B-cell Lymphoma (PMBCL)|High-grade B-cell Lymphoma|Grade 3b Follicular Lymphoma|Mantle Cell Lymphoma
Interventions: DRUG: CD79b-19 CAR T cells|DRUG: Cyclophosphamide|DRUG: Fludarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PD-L1 Imaging in Non Small Cell Lung Cancer' (PINNACLE)
Status: COMPLETED
Conditions: Non Small Cell Lung Cancer
Interventions: DIAGNOSTIC_TEST: 89Zr-avelumab PET|DRUG: Avelumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Universal Influenza A Vaccine in Healthy Adults
Status: COMPLETED
Conditions: Human Influenza
Interventions: BIOLOGICAL: UFluA 20 µg each antigen/dose|BIOLOGICAL: UFluA 60 µg each antigen/dose|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of JNJ-64264681 in Participants With Non-Hodgkin Lymphoma and Chronic Lymphocytic Leukemia
Status: ACTIVE_NOT_RECRUITING
Conditions: Lymphoma, Non-Hodgkin|Leukemia, Lymphocytic, Chronic, B-Cell
Interventions: DRUG: JNJ-64264681
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Management of Signs and Symptoms Associated With Dry Eye Disease
Status: TERMINATED
Conditions: Dry Eye Syndromes
Interventions: DEVICE: Self retained cryopreserved amniotic membrane|OTHER: lifitegrast ophthalmic solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: To Assess the Efficacy of High-Volume Plasma Exchange and GCSF Versus GCSF Alone in Patients of Acute on Chronic Liver Failure (ACLF).
Status: WITHDRAWN
Conditions: Acute-On-Chronic Liver Failure
Interventions: DRUG: Standard Medical Therapy|BIOLOGICAL: Plasma Exchange|BIOLOGICAL: GCSF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HOPE Consortium Trial to Reduce Pain and Opioid Use in Hemodialysis
Status: COMPLETED
Conditions: End Stage Renal Disease|Chronic Pain|Opioid Dependence
Interventions: BEHAVIORAL: Pain Coping Skills Training (PCST)|DRUG: Buprenorphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TeLIPro Health Program - Active With Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DEVICE: Scale|DEVICE: Step counter|DEVICE: Blood glucose meter with test stripes|OTHER: Access to the online portal|OTHER: Telemedical coaching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: To Evaluate the Impact of Oral Flecainide on Quality of Life in Patients With Paroxysmal Atrial Fibrillation
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DRUG: Flecainide controlled release
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigation of the Efficiency of Spinal Mobilization in Patients With Adolescent Idiopathic Scoliosis
Status: COMPLETED
Conditions: Adolescent Idiopathic Scoliosis
Interventions: OTHER: Spinal mobilization|OTHER: Core stabilization exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Sintilimab Combined With Reduction of Cycles of Chemotherapy in Resectable Oral Cavity or Oropharyngeal Squamous Cell Carcinoma (OOC-002)
Status: RECRUITING
Conditions: Oral Cavity Squamous Cell Carcinoma|Oral Squamous Cell Carcinoma|Oropharyngeal Squamous Cell Carcinoma
Interventions: DRUG: Sintilimab, Nab-paclitaxel, Carboplatin|PROCEDURE: Surgical resection|DRUG: Sintilimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Different Techniques on The Efficacy of Anaesthesia in Mandibular Molars With Acute Irreversible Pulpitis
Status: COMPLETED
Conditions: Pulpitis - Irreversible
Interventions: DRUG: Dexamethasone sodium phosphate injection|OTHER: 1,1,1,2 tetrafluoroethane|OTHER: intraoral soft tissue cryotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Testing the Use of Combination Therapy in Patients With Persistent Low Level Acute Myeloid Leukemia Following Initial Treatment, The ERASE Study (A MyeloMATCH Treatment Trial)
Status: NOT_YET_RECRUITING
Conditions: Acute Myeloid Leukemia|Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome|Acute Myeloid Leukemia Arising From Previous Myeloproliferative Neoplasm|Acute Myeloid Leukemia Post Cytotoxic Therapy|Secondary Acute Myeloid Leukemia
Interventions: DRUG: Azacitidine|PROCEDURE: Bone Marrow Aspiration and Biopsy|DRUG: Cytarabine|PROCEDURE: Echocardiography|DRUG: Liposome-encapsulated Daunorubicin-Cytarabine|PROCEDURE: Multigated Acquisition Scan|DRUG: Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Barrett&Apos;s Intervention for Dysplasia by Endoscopy
Status: COMPLETED
Conditions: Barretts Esophagus|Esophageal High-Grade Intraepithelial Neoplasia|Esophageal Cancer Stage I
Interventions: PROCEDURE: ER plus RFA|PROCEDURE: ER plus APC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Dose Escalation Study of ZG006 in Participants With Advanced Small Cell Lung Cancer or Neuroendocrine Carcinoma, Followed by Dose Expansion Study in Participants With Advanced Small Cell Lung Cancer
Status: NOT_YET_RECRUITING
Conditions: Small Cell Lung Cancer|Neuroendocrine Cancer
Interventions: BIOLOGICAL: ZG006
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT