pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Imetelstat in Combination With Paclitaxel (With or Without Bevacizumab) in Patients With Locally Recurrent or Metastatic Breast Cancer
Status: COMPLETED
Conditions: Locally Recurrent or Metastatic Breast Cancer
Interventions: DRUG: Imetelstat sodium|DRUG: Bevacizumab|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BMS-813160 With Nivolumab and Gemcitabine and Nab-paclitaxel in Borderline Resectable and Locally Advanced Pancreatic Ductal Adenocarcinoma (PDAC)
Status: COMPLETED
Conditions: Pancreatic Ductal Adenocarcinoma
Interventions: DRUG: BMS-813160|DRUG: Nivolumab|DRUG: Gemcitabine|DRUG: Nab-paclitaxel|PROCEDURE: Biopsy|PROCEDURE: Peripheral blood
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preoperative Analgesia in Non-gynecological Cancerous Women Who Underwent Elective Total Abdominal Hysterectomy
Status: COMPLETED
Conditions: Total Abdominal Hysterectomy ,Pain , Acute Postoperative,Gabapentin , Celecoxib
Interventions: PROCEDURE: Total abdominal hysterectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Home Biofeedback or Pelvic Floor Physical Therapy for Postpartum Urinary Incontinence.
Status: RECRUITING
Conditions: Urinary Incontinence|Pelvic Floor Disorders
Interventions: DEVICE: Pericoach® by Analytica|OTHER: Pelvic Floor Physical Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Zenith® Fenestrated Abdominal Aortic Aneurysm (AAA) Endovascular Graft Continued Access Study
Status: APPROVED_FOR_MARKETING
Conditions: Abdominal Aortic Aneurysms|Aorto-iliac Aneurysms|Juxtarenal Aneurysms
Interventions: DEVICE: Zenith® Fenestrated AAA Endovascular Graft
Study Type: EXPANDED_ACCESS
Clinical trial: A Multicentric Validation Study on the Accuracy of Artificial Intelligence Assisted System in Clinical Application of Digestive Endoscopy
Status: ACTIVE_NOT_RECRUITING
Conditions: Gastrointestinal Disease|Endoscopy|Artificial Intelligence
Interventions: DIAGNOSTIC_TEST: Endoscopists refer to AI for diagnosis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Hospital Airway Resuscitation Trial
Status: RECRUITING
Conditions: Cardiac Arrest|Respiratory Failure
Interventions: PROCEDURE: A strategy of first choice supraglottic airway|PROCEDURE: A strategy of first choice endotracheal intubation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Omega-3 vs Very Low Calorie Diet for Liver Size Reduction
Status: UNKNOWN
Conditions: Obesity, Morbid|Obesity|NAFLD|NASH - Nonalcoholic Steatohepatitis
Interventions: DIETARY_SUPPLEMENT: Omega-3|DIETARY_SUPPLEMENT: Very Low Calorie Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety of SNK01 in Subjects With Pathologically Confirmed Metastatic and/or Unresectable Cancer Refractory to Conventional Therapy
Status: COMPLETED
Conditions: Refractory Cancer|Metastatic Cancer|Recurrent Cancer|Unresectable Carcinoma|Solid Tumor, Adult|Advanced Cancer|Advanced Solid Tumor
Interventions: BIOLOGICAL: SNK01|DRUG: Avelumab|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Effectiveness and Safety Study of Inhaled JNJ 49095397 (RV568) in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: JNJ 49095397|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Reduced-intensity Immunoablation and Autologous Hematopoietic Stem Cell Transplantation (AHSCT) for Multiple Sclerosis
Status: UNKNOWN
Conditions: Multiple Sclerosis
Interventions: BIOLOGICAL: Autologous Hematopoietic Stem Cell|DRUG: BEAM Regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: G-CSF Administration in IVF in a Preferable Preceptive Endometrium Score
Status: UNKNOWN
Conditions: Women Infertility
Interventions: PROCEDURE: Endometrial scratch|DRUG: G-CSF administration|DRUG: Saline Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study to Verify Proper Detection of Supraventricular Tachyarrhythmia With Single-Lead Dual-Chamber Implantable Cardioverter-Defibrillators (ADRIA)
Status: COMPLETED
Conditions: Tachyarrhythmia
Interventions: DEVICE: Implantable cardioverter-defibrillator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Metabolism and Absorption of Anthocyanins From Extract and Whole Blueberry Powder Confections in Healthy Adults
Status: ACTIVE_NOT_RECRUITING
Conditions: Healthy Diet|Nutrition Aspect of Cancer
Interventions: OTHER: Blueberry Powder Food Product|OTHER: Dietary Intervention|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Evaluate JAK Inhibitor Cream in EGFR-inhibitor-induced Skin Rash
Status: ACTIVE_NOT_RECRUITING
Conditions: Acneiform Eruptions
Interventions: DRUG: Cream containing JAK Inhibitor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: REMOTE Ischemic Perconditioning Among Acute Ischemic Stroke Patients ( REMOTE-CAT)
Status: ACTIVE_NOT_RECRUITING
Conditions: Ischemic Stroke
Interventions: OTHER: Remote ischemic perconditioning|OTHER: Sham remote perconditioning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Posterior vs. Anterior Tympanostomy Tube Placement
Status: RECRUITING
Conditions: Otitis Media in Children|Chronic Otitis Media With Effusion|Recurrent Acute Otitis Media
Interventions: DEVICE: Tympanostomy tube
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Single Dose Study to Evaluate Dose-proportionality of Vortioxetine Hemihydrobromide Orally Disintegrating Tablets
Status: COMPLETED
Conditions: Major Depressive Disorder (MDD
Interventions: DRUG: Vortioxetine Hemihydrobromide Orally Disintegrating Tablets 5mg|DRUG: Vortioxetine Hemihydrobromide Orally Disintegrating Tablets 10mg|DRUG: Vortioxetine Hemihydrobromide Orally Disintegrating Tablets 20mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Apixaban Versus Warfarin for the Management of Post-operative Atrial Fibrillation
Status: COMPLETED
Conditions: Coronary Artery Bypass Grafting|Postoperative Atrial Fibrilation|Stroke|Systemic Embolism|Deep Venous Thrombosis
Interventions: DRUG: Apixaban|DRUG: Warfarin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Perımenopausal Women's Attıtudes Towards Menopause and Spırıtual Well-Beıng
Status: ENROLLING_BY_INVITATION
Conditions: Menopause|Activity, Motor|Attitude
Interventions: BEHAVIORAL: TRAINING AND EXERCISE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: TOP 2301: Neoadjuvant Chemo for NSCLC
Status: NOT_YET_RECRUITING
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: Alirocumab|DRUG: Cemiplimab|DRUG: Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Outpatient Study of the Effectiveness and Safety of Depakote ER in the Treatment of Mania/Bipolar Disorder in Children and Adolescents
Status: COMPLETED
Conditions: Bipolar Disorder
Interventions: DRUG: Divalproex Sodium Extended-Release Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Gemcitabine With Pazopanib as Second Line Treatment in Patient With Metastatic or Relapsed Uterine
Status: COMPLETED
Conditions: Leiomyosarcoma
Interventions: DRUG: pazopanib + gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Does the Pain Experienced During Orthodontic Treatment and Bracket Removal Depend on the Architecture of the Bracket?
Status: COMPLETED
Conditions: Debonding|Orthodontic Brackets
Interventions: DEVICE: bracket removal pliers, LODI
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tadalafil for Severe Pulmonary Hypertension Due to Chronic Obstructive Pulmonary Disease
Status: RECRUITING
Conditions: Pulmonary Hypertension|Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Tadalafil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Immediate Effects of Whole Body Vibration on Neuromuscular Performance of Quadriceps Femoris and Balance
Status: COMPLETED
Conditions: Neuromuscular Performance and Balance
Interventions: OTHER: Vibration at 30 Hz|OTHER: Vibration at 50 Hz
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Radium-223 Dichloride (BAY88-8223) in Castration-Resistant (Hormone-Refractory) Prostate Cancer Patients With Bone Metastases
Status: NO_LONGER_AVAILABLE
Conditions: Prostatic Neoplasms
Interventions: DRUG: Radium-223 dichloride (BAY88-8223)
Study Type: EXPANDED_ACCESS
Clinical trial: Venetoclax and Ibrutinib in Treating in Participants With Chronic Lymphocytic Leukemia and Ibrutinib Resistance Mutations
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Lymphocytic Leukemia|Ibrutinib Resistance
Interventions: DRUG: Ibrutinib|OTHER: Laboratory Biomarker Analysis|DRUG: Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect on Pain and Satisfaction of Two Different Non-Pharmacological Methods Used During Coronavirus (Covid-19) Vaccination
Status: UNKNOWN
Conditions: Individual Satisfaction|Pain Management
Interventions: OTHER: The stress ball|DEVICE: The Buzzy® device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Evaluate Safety and Pharmacokinetics/Pharmacodynamics of Sustained Release(SR) Exenatide
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: SR Exenatide (PT302)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: RT or No RT Following Chemotherapy in Treating Patients With Stage III/IV Hodgkin's Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Lymphoma
Interventions: BIOLOGICAL: bleomycin sulfate|DRUG: doxorubicin hydrochloride|DRUG: mechlorethamine hydrochloride|DRUG: prednisone|DRUG: procarbazine hydrochloride|DRUG: vinblastine sulfate|DRUG: vincristine sulfate|RADIATION: low-LET cobalt-60 gamma ray therapy|RADIATION: low-LET photon therapy|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: A Trial of Dextromethorphan for Treatment of Major Depressive Disorder
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: Dextromethorphan Hydrobromide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized, Double-Blind, Placebo-Controlled Study of Omalizumab for Idiopathic Anaphylaxis
Status: COMPLETED
Conditions: Anaphylaxis|Hypotension|Bronchospasm|Angioedema
Interventions: DRUG: Epinephrine|DRUG: Omalizumab (Xolair)|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Anti-proteinuric Effect of Calcitriol in Non-diabetic Kidney Disease Patients
Status: UNKNOWN
Conditions: Proteinuria
Interventions: DRUG: Calcitriol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Pentostatin and Low Dose TBI With Allogenic Peripheral Blood Stem Cell Transplant
Status: COMPLETED
Conditions: Acute Myelogenous Leukemia|Acute Lymphocytic Leukemia|Chronic Myelogenous Leukemia|Chronic Lymphocytic Leukemia|Myelodysplastic Syndromes|Multiple Myeloma|Non-Hodgkins Lymphoma|Hodgkins Disease|Peripheral T-cell Lymphoma
Interventions: DRUG: Pentostatin|RADIATION: Total-body irradiation (TBI)|DRUG: Cyclosporine A (CsA)|DRUG: Mycophenolate Mofetil (MMF)|DRUG: G-CSF
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacological Treatment Targeting Endotypic Traits of Obstructive Sleep Apnea
Status: NOT_YET_RECRUITING
Conditions: Obstructive Sleep Apnea of Adult
Interventions: DRUG: Atomoxetine 80mg combined with oxybutynin 5mg|DRUG: Venlafaxine 37.5mg|DRUG: Atomoxetine 80mg combined with trazodone 100mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Model for the Integral Assessment of Chronic Disease Management Supported in Information Technology and Communication.
Status: COMPLETED
Conditions: Chronic Disease
Interventions: DEVICE: Platform NOMHADchronic|OTHER: Phone-based care group|OTHER: Usual care group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose:
Clinical trial: The Combination Effect of Citicoline and Omega-3
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Placebo supplement|DIETARY_SUPPLEMENT: Citicoline and Omega-3 supplement|DIETARY_SUPPLEMENT: Omega-3 supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Mild Resistive Expiratory Breathing Technique On Spinal Cord Injury
Status: COMPLETED
Conditions: Spinal Cord Injuries
Interventions: OTHER: Mild Resistive Expiratory Technique|OTHER: Conventional Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Incidence of Postoperative Pain After Root Canal Preparation Using Three Different Instruments
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: PROCEDURE: WaveOne Gold|PROCEDURE: Reciproc Blue|PROCEDURE: ProTaper Next
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: To Assess Safety and Efficacy of Bolus Versus Continuous Infusion of Terlipressin in Acute Variceal Bleeding
Status: COMPLETED
Conditions: Acute Variceal Bleeding
Interventions: DRUG: Terlipressin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunomodulatory Drugs (Lenalidomide With or Without Pomalidomide) in Combination With a Corticosteroid Drug (Dexamethasone) for the Treatment of Multiple Myeloma
Status: ACTIVE_NOT_RECRUITING
Conditions: Plasma Cell Myeloma|Recurrent Plasma Cell Myeloma|Refractory Plasma Cell Myeloma|Smoldering Plasma Cell Myeloma
Interventions: PROCEDURE: Bone Marrow Biopsy|DRUG: Dexamethasone|DRUG: Lenalidomide|DRUG: Pomalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Torcetrapib/Atorvastatin vs Atorvastatin Alone or Placebo in Patients With High Cholesterol
Status: COMPLETED
Conditions: Hyperlipidemia
Interventions: DRUG: torcetrapib/atorvastatin|DRUG: atorvastatin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Study of Amantadine for Cognitive Dysfunction in Patients With Long-Covid
Status: RECRUITING
Conditions: Long COVID|Post-Acute COVID-19 Syndrome
Interventions: DRUG: Amantadine|OTHER: Physical, Occupational, Speech Therapy|OTHER: Provider Counseling|OTHER: Medications for symptoms management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Safety, Efficacy and Tolerability of Secukinumab Versus Placebo, in Combination With SoC Therapy, in Patients With Active Lupus Nephritis
Status: TERMINATED
Conditions: Lupus Nephritis
Interventions: DRUG: secukinumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety & Tolerability of the IRay System in Subjects With Exudative Choroidal Neovascularization (CNV) Secondary to Age-Related Macular Degeneration (AMD)
Status: UNKNOWN
Conditions: Age-Related Macular Degeneration|Wet Age-Related Macular Degeneration|Macular Degeneration|Eye Diseases|Retinal Diseases
Interventions: DEVICE: IRay
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Responses to Colloid Infusions
Status: COMPLETED
Conditions: Laparoscopic Cholecystectomy
Interventions: OTHER: Succinylated gelatine, 40g/L, (Gelofusine - B Braun)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Desvenlafaxine Succinate (DVS) for Major Depressive Disorder (MDD) in Midlife Men and Women
Status: UNKNOWN
Conditions: Major Depressive Disorder|Menopausal Staging and Vasomotor Symptoms (for Females)
Interventions: DRUG: Desvenlafaxine Succinate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Comparing Onyx and TRUFILL in Brain Arteriovenous Malformations (AVMs)
Status: COMPLETED
Conditions: Brain Arteriovenous Malformations
Interventions: DEVICE: Onyx|DEVICE: TRUFILL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of the Individual and Family Self-Management of Fall Prevention Program on Balance Ability and Fall Efficacy Among Chinese With Post-Stroke
Status: NOT_YET_RECRUITING
Conditions: Post-stroke People
Interventions: BEHAVIORAL: individual and family self-management (IFSM) fall prevention program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Channa Striatus Extract on Albumin and Hs-CRP ESRD
Status: COMPLETED
Conditions: End-Stage Renal Disease|Inflammation
Interventions: DIETARY_SUPPLEMENT: Channa Striatus extract|DIETARY_SUPPLEMENT: Maltodextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Multiparametic Metabolic and Hypoxic PET/MRI for Disease Assessment in High Grade Glioma
Status: RECRUITING
Conditions: High Grade Glioma
Interventions: DRUG: O-(2-[18F]Fluoroethyl)-L-tyrosine, [18F]-FET with PET/MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation of an Electronic CKD Clinical Decision Support System (CDSS) in Clinical Care
Status: COMPLETED
Conditions: Hypertension|Renal Insufficiency, Chronic
Interventions: OTHER: Clinical Decision Support System (CDSS)|OTHER: Clinic Decision Sup System + Pharmacist
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Clinical Trial to Evaluate the Safety and Efficacy of IM92 CAR-T Cells Therapy in Patients With Advanced Gastric or Pancreatic Adenocarcinoma
Status: UNKNOWN
Conditions: Advanced Solid Tumors|Gastric Cancer|Esophagogastric Junction Cancer|Pancreatic Cancer
Interventions: DRUG: IM92 CAR-T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mandibular Response After Maxillary Orthopedic Expansion in Class II Growing Subjects
Status: COMPLETED
Conditions: Malocclusion, Angle Class II|Malocclusion
Interventions: DEVICE: Bonded RME (Rapid Maxillary Expander) appliance|DEVICE: Banded RME (Rapid Maxillary Expander) appliance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study for Evaluation of Safety and Efficacy of PADN to Treat Combined Post- and Pre- Capillary Pulmonary Hypertension Associated With Chronic Heart Failure
Status: NOT_YET_RECRUITING
Conditions: Pulmonary Hypertension|Heart Failure
Interventions: PROCEDURE: Pulmonary Artery Denervation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Open Study to Assess the Safety and Pharmacokinetics of Fluorothyazinone as a Single-Dose Administration or a Treatment Course in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: Fluorothyazinone 300 mg|DRUG: Fluorothyazinone 600 mg|DRUG: Fluorothyazinone 3900 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Letrozole as a Prophylaxis From GTN for Complete Mole Patients
Status: UNKNOWN
Conditions: Gestational Trophoblastic Disease
Interventions: PROCEDURE: Suction evacuation|DRUG: Letrozole tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pemetrexed Disodium, Carboplatin, and Radiation Therapy With or Without Cetuximab in Treating Patients With Stage III Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer
Interventions: BIOLOGICAL: cetuximab|DRUG: carboplatin|DRUG: pemetrexed disodium|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Success in Health: Impacting Families Together
Status: COMPLETED
Conditions: Childhood Obesity
Interventions: BEHAVIORAL: FBT for Pediatric Weight Management by Professionals|BEHAVIORAL: FBT for Pediatric Weight Management by Peers|BEHAVIORAL: Peer Interventionists
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Surfactant for Neonate With Acute Respiratory Distress Syndrome (ARDS)
Status: RECRUITING
Conditions: ARDS|RDS|Surfactant
Interventions: DRUG: surfactant combined with mechanical ventilation (MV)|DRUG: mechanical ventilation (MV)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Amlodipine Versus Bisoprolol on Hypertensive Patients With End-stage Renal Disease on Maintenance Hemodialysis.
Status: COMPLETED
Conditions: Hypertension, Renal
Interventions: DRUG: Bisoprolol Fumarate 5-10 mg|DRUG: Amlodipine 5-10 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Induction of Immune-mediated aBscOpal Effect thrOugh STEreotactic Radiation Therapy in Metastatic Melanoma Patients Treated by PD-1 + CTLA-4 Inhibitors (BOOSTER MELANOMA)
Status: TERMINATED
Conditions: Melanoma
Interventions: COMBINATION_PRODUCT: Nivolumab + Ipilimumab|COMBINATION_PRODUCT: Combined treatment schema
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Safety and Efficacy of Fabagal® (Agalsidase Beta) in Patients With Fabry Disease
Status: RECRUITING
Conditions: Fabry Disease
Interventions: BIOLOGICAL: Fabagal® (Agalsidase beta)|DRUG: Active comparator (Agalsidase beta)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Positive Expiratory Pressure on Right Ventricular Function in Patients With Respiratory Distress Syndrome
Status: COMPLETED
Conditions: Respiratory Distress Syndrome, Adult
Interventions: DEVICE: ventilatory strategies with pressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Al18F-NOTA-LM3 With 68Ga-DOTATATE and 68Ga-NODAGA-LM3 PET/CT in Patients With Well-differentiated Neuroendocrine Tumors
Status: RECRUITING
Conditions: Neuroendocrine Tumors
Interventions: DIAGNOSTIC_TEST: Al18F-NOTA-LM3|DIAGNOSTIC_TEST: 68Ga-DOTATATE|DIAGNOSTIC_TEST: Al18F-NOTA-LM3|DIAGNOSTIC_TEST: 68Ga-NODAGA-LM3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Warming Sensation Intensity and Acceptability of the Flavour, Local Tolerability of Paracetamol 500 mg + Pseudoephedrine 30 mg Syrup in Patients Suffering a URTI
Status: COMPLETED
Conditions: Upper Respiratory Infections
Interventions: DRUG: IFF flavor 316 282, Paracetamol, Pseudoephedrine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Study to Evaluate Safety, Pharmacokinetics and Therapeutic Activity of RO6874281 as a Combination Therapy in Participants With Unresectable Advanced and/or Metastatic Renal Cell Carcinoma (RCC)
Status: COMPLETED
Conditions: Renal Cell Carcinoma
Interventions: DRUG: Atezolizumab|DRUG: Bevacizumab|DRUG: RO6874281
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phamacokinetics and Safety Profiles of DA-5210 10/500mg in Healthy Subjects at Fasting State
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: DA-5210 10/500mg|DRUG: DA-5210-R 10/500mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of the CHESS eHealth Cancer Support Intervention in Population-based Care
Status: COMPLETED
Conditions: Primary Breast Cancer
Interventions: BEHAVIORAL: Enhanced ICCS with KPNW web resources and the Comprehensive Health Enhancement Support System (CHESS.)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Investigation of Naltrexone for Pathological Gambling
Status: COMPLETED
Conditions: Pathological Gambling
Interventions: DRUG: Naltrexone|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PARK-FIT. Treadmill vs Cycling in Parkinson´s Disease. Definition of the Most Effective Model in Gait Reeducation
Status: UNKNOWN
Conditions: Parkinson Disease
Interventions: OTHER: Non pharmacological therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Individualized Perioperative Open-Lung Ventilatory Strategy During One-Lung Ventilation
Status: UNKNOWN
Conditions: Thoraric Surgery|Surgery Time Expected More Than Two Hours
Interventions: PROCEDURE: Alveolar recruitment maneuver|PROCEDURE: PEEP Titration Trial|PROCEDURE: Lung protective ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Study of Tirzepatide (LY3298176) Once a Week Versus Insulin Glargine Once a Day in Participants With Type 2 Diabetes and Increased Cardiovascular Risk
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Tirzepatide|DRUG: Insulin Glargine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Immunotherapy Drugs Nivolumab and Ipilimumab in Patients w/Resectable Malignant Peritoneal Mesothelioma
Status: COMPLETED
Conditions: Mesothelioma|Peritoneal Mesothelioma
Interventions: DRUG: Nivolumab|DRUG: Ipilimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preoperative Fractionated Radiation Therapy Versus Stereotactic Body Radiation Therapy for Resectable or Borderline Resectable, or Locally Advanced Type A Pancreatic Adenocarcinoma
Status: RECRUITING
Conditions: Pancreatic Cancer
Interventions: RADIATION: Stereotactic Body Radiation Therapy|RADIATION: Preoperative Fractionated Radiation Therapy and Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Study of Sonrotoclax Combined With Chemotherapy in the Treatment of Newly Diagnosed Acute Myeloid Leukemia
Status: NOT_YET_RECRUITING
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: sonrotoclax|DRUG: idarubicin/daunorubicin|DRUG: Cytarabine|DRUG: Azacitidine|PROCEDURE: allo-HSCT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Study of Pyrotinib in Previously Treated Patients With NSCLC Having EGFR or ERBB2 Exon 20 Insertion Mutation
Status: UNKNOWN
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: Pyrotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: C3G/Primary IC-MPGN EAP
Status: AVAILABLE
Conditions: C3G|IC-MPGN|C3 Glomerulopathy|C3 Glomerulonephritis|Complement 3 Glomerulopathy|Complement 3 Glomerulopathy (C3G)|Complement 3 Glomerulonephritis|Dense Deposit Disease|DDD|Membranoproliferative Glomerulonephritis|Membranoproliferative Glomerulonephritis (MPGN)|Immune Complex Membranoproliferative Glomerulonephritis (IC-MPGN)
Interventions: DRUG: Pegcetacoplan
Study Type: EXPANDED_ACCESS
Clinical trial: Seizure Rescue Medication (RM) as Part of a Comprehensive Epilepsy Self-management Package of Care
Status: RECRUITING
Conditions: Epilepsy
Interventions: BEHAVIORAL: SMART RM|DRUG: Valtoco Nasal Product
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Clinical Impact of 2 Types of Mandibular Retention Devices - Narval O.R.M CadCam Design vs Narval O.R.M Traditional Design - on Obstructive Sleep Apnea (OSA) Therapy: ESTAMPS Study
Status: COMPLETED
Conditions: Obstructive Sleep Apnea Syndrome
Interventions: DEVICE: Mandibular Retention Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Individualized PEEP on Postoperative Pulmonary Complication in Bariatrics
Status: RECRUITING
Conditions: Mechanical Ventilation Pressure High|Bariatric Surgery Candidate
Interventions: OTHER: titated PEEP to best static compliance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Impact of Metformin on Peripheral Arterial Calcification in Type 1 Diabetes
Status: RECRUITING
Conditions: Type 1 Diabetes|Peripheral Arterial Calcification
Interventions: DRUG: Metformin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Epidemiologic Multicenter Prospective Study in Advanced NSCLC (Non Small Cell Lung Cancer) Patients With PDL1 (Protein Death Ligand 1) Expression.
Status: COMPLETED
Conditions: Lung Cancer
Interventions: OTHER: Assessment of PDL1 expression
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Observational Study on Safety and Efficacy of Biphasic Insulin Aspart in Type 2 Diabetes Patients
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: biphasic insulin aspart 30|DRUG: biphasic insulin aspart 50|DRUG: biphasic insulin aspart 70
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effectiveness of Zinc Supplementation in Management of Patients With Symptomatic Benign Migratory Glossitis
Status: COMPLETED
Conditions: Benign Migratory Glossitis
Interventions: DRUG: Zinc Sulfate 110 MG (Zinc 25 MG) Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Melatonin as a Novel Antioxidant and Free Radicals Scavenger in Neonatal Sepsis
Status: COMPLETED
Conditions: Neonatal Sepsis
Interventions: DRUG: Melatonin 10 mg|COMBINATION_PRODUCT: Conventional treatment of neonatal sepsis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Avelumab (Bavencio) With IL-15 in Subjects With Clear-Cell Renal Carcinoma
Status: TERMINATED
Conditions: Clear-Cell Renal Carcinoma
Interventions: DRUG: rhIL-15|BIOLOGICAL: Avelumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Maternal Oxygen Use During Delivery and Cord Blood Superoxide Dismutase
Status: COMPLETED
Conditions: Oxidative Stress|Fetal Distress
Interventions: OTHER: Oxygen|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: DIAGNOSTIC
Clinical trial: Periodic Presumptive Treatment vs. doxyPEP for STI Control in Kenyan MSM
Status: NOT_YET_RECRUITING
Conditions: Gonorrhea Male|Chlamydia (Male)|Syphilis Male
Interventions: DRUG: WHO-recommended periodic presumptive treatment|DRUG: Doxycycline post-exposure prophylaxis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Translational Neuropsychopharmacology Research of Nicotine Addiction
Status: COMPLETED
Conditions: Nicotine Dependence, Cigarettes
Interventions: DRUG: Varenicline (VRN)|DRUG: N-Acetylcysteine (NAC)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Efficacy of Thrombosuction in Primary Percutaneous Coronary Intervention of Acute Myocardial Infarction
Status: UNKNOWN
Conditions: Acute Myocardial Infarction
Interventions: DEVICE: Endeavor resolute or Resolute integrity (Medtronic)|DEVICE: Export Aspiration Catheter, Endeavor resolute or Resolute integrity (Medtronic)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Recombinant Birch Pollen Allergen in the Treatment of Allergic Rhinoconjunctivitis
Status: COMPLETED
Conditions: Birch Pollen Allergy
Interventions: BIOLOGICAL: Recombinant birch pollen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: "En Bloc" Resection of NMIBC: a Prospective， Single Centre，Randomized Study
Status: UNKNOWN
Conditions: Non-muscle Invasive Bladder Cancer
Interventions: DEVICE: Laser en Bloc Resection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Metal Allergy In-Stent Restenosis Study
Status: UNKNOWN
Conditions: Metal Allergy|Contact Allergy|Restenoses, Coronary|In-stent Restenosis|Coronary Artery Disease
Interventions: BIOLOGICAL: In-stent restenosis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Low Dose Growth Hormone (GH) on Insulin Sensitivity and Cortisol Production Rates
Status: COMPLETED
Conditions: Growth Hormone Deficiency
Interventions: DRUG: Growth hormone (Genotropin)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Impact of Diet on the Gut-Microbiota-Brain Axis
Status: RECRUITING
Conditions: Healthy
Interventions: OTHER: Fermented Foods|OTHER: High Fibre|OTHER: Combined Diet|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of Non-Surgical and Arthroscopic Treatment for Hip Microinstability
Status: RECRUITING
Conditions: Musculoskeletal Abnormalities|Hip Injuries
Interventions: PROCEDURE: physiotherapy|PROCEDURE: arthroscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Study Comparing Different Modalities of Oxygen Delivery During Assessment of Functional Exercise Capacity
Status: COMPLETED
Conditions: COPD
Interventions: DEVICE: Standard oxygen delivery system|DEVICE: Homefill oxygen delivery system|DEVICE: Helios oxygen delivery system|DEVICE: FreeStyle oxygen system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long-term Effect of Electromagnetic Field in Treatment of Patients With Osteopenia or Osteoporosis
Status: COMPLETED
Conditions: Osteopenia or Osteoprosis
Interventions: OTHER: Pulsed Electromagnetic Field (PEMF)|OTHER: Exercise Program|OTHER: Placebo PEMF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Compare Intraperitoneal Insulin to Subcutaneous Insulin Administration in Type 1 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: DEVICE: MIP 2007C implantable insulin pump|DEVICE: continuous subcutaneous insulin infusion (CSII) or MDI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Pomegranate Seed Oil and Mediterranean Diet on MCI
Status: RECRUITING
Conditions: Mild Cognitive Impairment
Interventions: DIETARY_SUPPLEMENT: Pomegranate oil, Mediterranean Diet|DIETARY_SUPPLEMENT: Mediterranean Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Formulated PSTA Injection Versus PATA Alone in the Management of Macular Edema Secondary to Non-ischemic Retinal Vein Occlusions
Status: COMPLETED
Conditions: Macula Edema
Interventions: DRUG: Triamcinolone Acetonide and sodium hyaluronate and chondroitin sulfate|DRUG: Triamcinolone Acetonide alone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of CDX-1307, in Patients With Incurable Breast, Colorectal, Pancreatic, Ovarian or Bladder Cancer (CDX 1307-01)
Status: COMPLETED
Conditions: Breast Cancer|Colorectal Cancer|Pancreatic Cancer|Bladder Cancer|Ovarian Cancer
Interventions: BIOLOGICAL: CDX1307
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Melatonin Supplementation in Postmenopausal Women With H. Pylori-associated Dyspepsia
Status: COMPLETED
Conditions: Melatonin Deficiency
Interventions: DRUG: Melatonin|OTHER: placebo|DRUG: Pantoprazole 40mg|DRUG: Amoxicillin|DRUG: Levofloxacin 500mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Chewy Satiety - the Interplay Between Food Structure, Oral Processing and Satiety
Status: COMPLETED
Conditions: Subjective Appetite and Satiety
Interventions: OTHER: Rye products with varying structures
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety and Efficacy of Targeting PP2A in Ovarian Clear Cell Carcinoma Using Dostarlimab and LB-100
Status: RECRUITING
Conditions: Ovarian Clear Cell Carcinoma
Interventions: DRUG: Dostarlimab|DRUG: LB-100
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intravitreal Bevacizumab for Diabetic Retinopathy
Status: TERMINATED
Conditions: Severe Nonproliferative|Proliferative Diabetic Retinopathy|Active Photocoagulated Diabetic Retinopathy
Interventions: DRUG: intravitreal bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Transcervical Foley Catheter and Prostaglandins for Induction of Labor at Term
Status: COMPLETED
Conditions: Failed Induction of Labor
Interventions: DEVICE: Transcervical foley catheter, Prostaglandins
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vinorelbine in Unresectable or Metastatic Esophageal and Gastric Adenocarcinoma
Status: COMPLETED
Conditions: Esophageal Cancer|Gastric Cancer|Stomach Cancer
Interventions: DRUG: Vinorelbine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Itraconazole Administered as Inhaled Dry Powder in Adults With Asthma and ABPA
Status: TERMINATED
Conditions: ABPA
Interventions: DRUG: Itraconazole Powder|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Safety, and Pharmacokinetics of ES-481 in Adult Patients With Essential Tremors
Status: RECRUITING
Conditions: Tremor, Essential
Interventions: DRUG: ES-481|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Effect of SCH 900538 on Congestion in Subjects With Seasonal Allergic Rhinitis (Study P05031)(COMPLETED)
Status: COMPLETED
Conditions: Seasonal Allergic Rhinitis
Interventions: DRUG: SCH 900538|DRUG: Pseudoephedrine|DRUG: Placebo Capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of The Efficacy of Triazavirin Versus Oseltamivir in Egyptian Patients Infected With COVID-19
Status: UNKNOWN
Conditions: Covid19
Interventions: DRUG: standard treatment COVID-19 + Triazavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Study of GLPG1837 in Subjects With Cystic Fibrosis (G551D Mutation)
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: GLPG1837 dose 1|DRUG: GLPG1837 dose 2|DRUG: GLPG1837 dose 3
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Outcomes For Patients With Metastatic Renal Cell Carcinoma (mRCC) Who Received Sunitinib After 1st Line Immune-oncology (IO) Treatments
Status: COMPLETED
Conditions: Metastatic Renal Cell Carcinoma (mRCC)
Interventions: DRUG: sunitinib
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Musculoskeletal Nociceptive Pain in Participants With Neuromuscular Disorders
Status: COMPLETED
Conditions: Pompe Disease (Late-onset)|Myotonic Dystrophy Type 1 (DM1)|Myotonic Dystrophy Type 2|Spinal Muscular Atrophy Type 3|Inclusion Body Myositis, Sporadic|Facioscapulohumeral Muscular Dystrophy 1|Healthy
Interventions: DIAGNOSTIC_TEST: Beck depression inventory fast screen|DIAGNOSTIC_TEST: German Pain Inventory|DIAGNOSTIC_TEST: Brief Pain Inventory|DIAGNOSTIC_TEST: Fatigue Severity and Disability Scale (FSS)|DIAGNOSTIC_TEST: Quick Motor Function Test|DIAGNOSTIC_TEST: Handheld Dynamometry (HHD)|DIAGNOSTIC_TEST: Six-minute walk test (6MWT)|DIAGNOSTIC_TEST: Pressure pain threshold|DIAGNOSTIC_TEST: Myotonometer Assessment|DIAGNOSTIC_TEST: Vital signs|DIAGNOSTIC_TEST: Borg Scale
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p