pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Intravenous Tedisamil in the Rapid Conversion of Atrial Fibrillation or Flutter to Normal Sinus Rhythm in Female Subjects
Status: COMPLETED
Conditions: Atrial Fibrillation|Atrial Flutter
Interventions: DRUG: Tedisamil sesquifumarate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Study of Valganciclovir in the Treatment of Cytomegalovirus (CMV) Retinitis in Patients With AIDS
Status: COMPLETED
Conditions: Cytomegalovirus Retinitis|HIV Infections
Interventions: DRUG: Valganciclovir
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multiple Escalating Dose Study of BAY1093884 in Adults With Hemophilia A or B With or Without Inhibitors
Status: TERMINATED
Conditions: Hemophilia A and B
Interventions: DRUG: Befovacimab (BAY1093884)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I/II, a Single Arm, Open-label Study of Ofatumumab (GSK1841157) in Patients With Previously Treated Chronic Lymphocytic Leukemia
Status: COMPLETED
Conditions: Leukaemia, Lymphocytic, Chronic
Interventions: DRUG: ofatumumab 100 mg, 1000 mg / vial
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Post-operative Pain Control After Photorefractive Keratectomy Comparing Acetaminophen/Codeine vs Acetaminophen/Oxycodone
Status: COMPLETED
Conditions: Post-operative Pain Control
Interventions: DRUG: acetaminophen/codeine vs acetaminophen/oxycodone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Combination Chemotherapy and Oblimersen in Treating Patients With Advanced Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: BIOLOGICAL: oblimersen sodium|DRUG: fluorouracil|DRUG: leucovorin calcium|DRUG: oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, and Pharmacokinetic and Pharmacodynamic Characteristics of JP-2266 in Healthy Subjects
Status: UNKNOWN
Conditions: Diabetes Mellitus
Interventions: DRUG: JP-2266|DRUG: JP-2266 Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Oral Capsule Faecal Microbiota Transplantation for CPE Decolonization
Status: UNKNOWN
Conditions: Carbapenem-Resistant Enterobacteriaceae Infection
Interventions: BIOLOGICAL: Oral capsule faecal microbiota transplantation|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Naltrexone and Varenicline on Alcohol-Mediated Smoking Lapse
Status: COMPLETED
Conditions: Smoking
Interventions: DRUG: naltrexone|DRUG: varenicline|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Mepitel Film® in Preventing Epidermitis in Patients Receiving Radiation Therapy for Breast Cancer
Status: TERMINATED
Conditions: Breast Cancer|Radiotherapy; Adverse Effect, Dermatitis or Eczema|Radiotherapy Side Effect|Radiation Burn|Radiation Dermatitis|Radiotherapy; Complications
Interventions: DEVICE: Mepitel Film®
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: SF1126 in Recurrent or Progressive SCCHN and Mutations in PIK3CA Gene and/or PI-3 Kinase Pathway Genes
Status: TERMINATED
Conditions: Metastatic Squamous Neck Cancer With Occult Primary Squamous Cell Carcinoma
Interventions: DRUG: SF1126
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adaptive Cognitive Training on Cognitive Function in Elderly Hypertension Patients in the Community
Status: NOT_YET_RECRUITING
Conditions: Hypertension|Condition|Aging
Interventions: DEVICE: adaptive cognitive training|DEVICE: placebo cognitive training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Nebulized and Intravenous Colistin in Ventilator Associated-pneumonia
Status: TERMINATED
Conditions: Ventilator-associated Pneumonia
Interventions: DRUG: Intravenous colimycin|DRUG: Intravenous placebo|DRUG: Nebulized colimycin|DRUG: Nebulized placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: RPVI for Fluid Responsiveness in Children
Status: NOT_YET_RECRUITING
Conditions: Anesthesia|Fluid Responsiveness
Interventions: PROCEDURE: Fluid loading|DIAGNOSTIC_TEST: Transthoracic echocardiography|DIAGNOSTIC_TEST: PVI, RPVI|PROCEDURE: Tidal volume change
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Using Behavioural and Cultural Insights to Increase Colorectal Cancer Home-testing in Croatia
Status: RECRUITING
Conditions: Colorectal Cancer|Behavior Change
Interventions: BEHAVIORAL: Standard letter|BEHAVIORAL: Behaviorally informed letter|BEHAVIORAL: Home testing colorectal cancer kit
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SCREENING
Clinical trial: A Study Evaluating the Bioavailability of Oral Insulin (N11005)
Status: COMPLETED
Conditions: PK, PD, and Safety
Interventions: DRUG: N11005|DRUG: Novolin R
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study Evaluating the Efficacy and Safety of Miconazole Nitrate + Domiphen Bromide Vaginal Cream in the Treatment of Subjects With Acute Vulvovaginal Candidiasis
Status: UNKNOWN
Conditions: Acute Vulvovaginal Candidiasis
Interventions: DRUG: Miconazole Nitrate 2% + Domiphen Bromide Low Dose|DRUG: Miconazole Nitrate 2% + Domiphen Bromide High Dose|DRUG: Miconazole Nitrate 2%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Mostafa Maged Technique to Control and Prevent the Post-Partum Bleeding From the Lower Uterine Segment in Placenta Previa Cases
Status: COMPLETED
Conditions: Placenta Previa
Interventions: PROCEDURE: Mostafa Maged Technique
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effects of Platelet-rich Fibrin and Vitamin Dꝫ Injections on Root Resorption
Status: RECRUITING
Conditions: Root Resorption
Interventions: OTHER: Platelet-rich Fibrin|OTHER: Vitamin D3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Maternal Choline Intake on Choline Status and Health Biomarkers During Pregnancy and Lactation
Status: COMPLETED
Conditions: Pregnancy|Lactation
Interventions: DIETARY_SUPPLEMENT: choline chloride|DIETARY_SUPPLEMENT: Choline Chloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Comparative Study of Two Daily Disposable Contact Lenses in Higher Myopia Subjects
Status: COMPLETED
Conditions: Refractive Error|Myopia
Interventions: DEVICE: Delefilcon A contact lens|DEVICE: Narafilcon A contact lens|DEVICE: Spectacles
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of Anakinra (Plus Zinc) or Prednisone in Patients With Severe Alcoholic Hepatitis
Status: COMPLETED
Conditions: Alcoholic Hepatitis
Interventions: DRUG: Anakinra and Zinc|DRUG: Prednisone|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Renal Protective Effects of Remote Ischemic Preconditioning in Patients With Chronic Kidney Disease
Status: RECRUITING
Conditions: Chronic Kidney Diseases
Interventions: DEVICE: Remote ischemic conditioning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Surgery and Chemotherapy With or Without Chemotherapy After Surgery in Treating Patients With Ovarian, Fallopian Tube, Uterine, or Peritoneal Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: FIGO Stage IVA Ovarian Cancer|FIGO Stage IVB Ovarian Cancer|Platinum-Resistant Ovarian Carcinoma|Recurrent Fallopian Tube Carcinoma|Recurrent Ovarian Carcinoma|Recurrent Primary Peritoneal Carcinoma|Recurrent Uterine Corpus Carcinoma|Stage III Fallopian Tube Cancer AJCC v7|Stage III Ovarian Cancer AJCC v6 and v7|Stage III Primary Peritoneal Cancer AJCC v7|Stage III Uterine Corpus Cancer AJCC v7|Stage IIIA Fallopian Tube Cancer AJCC v7|Stage IIIA Ovarian Cancer AJCC v6 and v7|Stage IIIA Primary Peritoneal Cancer AJCC v7|Stage IIIA Uterine Corpus Cancer AJCC v7|Stage IIIB Fallopian Tube Cancer AJCC v7|Stage IIIB Ovarian Cancer AJCC v6 and v7|Stage IIIB Primary Peritoneal Cancer AJCC v7|Stage IIIB Uterine Corpus Cancer AJCC v7|Stage IIIC Fallopian Tube Cancer AJCC v7|Stage IIIC Ovarian Cancer AJCC v6 and v7|Stage IIIC Primary Peritoneal Cancer AJCC v7|Stage IIIC Uterine Corpus Cancer AJCC v7|Stage IV Fallopian Tube Cancer AJCC v6 and v7|Stage IV Ovarian Cancer AJCC v6 and v7|Stage IV Primary Peritoneal Cancer AJCC v7|Stage IV Uterine Corpus Cancer AJCC v7|Stage IVA Uterine Corpus Cancer AJCC v7|Stage IVB Uterine Corpus Cancer AJCC v7
Interventions: DRUG: Carboplatin|DRUG: Cisplatin|DRUG: Gemcitabine Hydrochloride|OTHER: Laboratory Biomarker Analysis|DRUG: Paclitaxel|DRUG: Pegylated Liposomal Doxorubicin Hydrochloride|OTHER: Quality-of-Life Assessment|PROCEDURE: Therapeutic Conventional Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open-label Comparison of Chronocort® Versus Standard Glucocorticoid Replacement Therapy
Status: WITHDRAWN
Conditions: Congenital Adrenal Hyperplasia
Interventions: DRUG: Chronocort®|DRUG: Standard Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Minimal Residual Disease-based Strategy With T-Cell Redirector After Treatment With Daratumumab, Bortezomib, Lenalidomide, and Dexamethasone (D-VRd) in Newly Diagnosed Multiple Myeloma
Status: NOT_YET_RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: Teclistamab|DRUG: Talquetamab|DRUG: Lenalidomide|DRUG: Bortezomib|DRUG: Daratumumab|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Long-Term Effectiveness of Three Anti-HIV Drug Regimens in HIV Infected Patients Who Have Never Been Exposed to Highly Active Antiretroviral Therapy (HAART)
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Indinavir sulfate|DRUG: Abacavir sulfate|DRUG: Nelfinavir mesylate|DRUG: Efavirenz|DRUG: Nevirapine|DRUG: Lamivudine|DRUG: Stavudine|DRUG: Didanosine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Determine the Absorption, Metabolism, and Routes of Excretion of (14C) Radiolabeled Ibrutinib in Healthy Male Participants
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DRUG: Ibrutinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Study a Non-invasive Neurostimulation Device on Urgency (Urinary) Incontinence Overactive Bladder (OAB)
Status: COMPLETED
Conditions: Overactive Bladder
Interventions: DEVICE: Non-invasive neurostimulation device|DEVICE: Non-invasive neurostimulation device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Does Aldosterone Cause Hypertension by a Non-Renal Mechanism?
Status: UNKNOWN
Conditions: Hypertension|Dialysis|Hyperaldosteronism
Interventions: DRUG: Eplerenone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Auditory and Tactile-kinesthetic Stimulation on Preterm Neonates
Status: COMPLETED
Conditions: Prematurity
Interventions: BEHAVIORAL: Tactile-kinesthetic stimulation|BEHAVIORAL: Recorded maternal voice
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Postoperative Progression of the Disease Following Extensive Versus Limited Mesenteric Excision for Crohn's Disease
Status: RECRUITING
Conditions: Postoperative Surgical Recurrence
Interventions: PROCEDURE: Extensive mesenteric resection|PROCEDURE: Limited mesenteric excision
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Ibrutinib, Rituximab, Etoposide, Prednisone, Vincristine Sulfate, Cyclophosphamide, and Doxorubicin Hydrochloride in Treating Patients With HIV-Positive Stage II-IV Diffuse Large B-Cell Lymphomas
Status: RECRUITING
Conditions: AIDS-Related Lymphoma|Ann Arbor Stage II Diffuse Large B-Cell Lymphoma|Ann Arbor Stage III Diffuse Large B-Cell Lymphoma|Ann Arbor Stage IV Diffuse Large B-Cell Lymphoma
Interventions: DRUG: Cyclophosphamide|DRUG: Doxorubicin Hydrochloride|DRUG: Etoposide|BIOLOGICAL: Filgrastim|DRUG: Ibrutinib|OTHER: Laboratory Biomarker Analysis|BIOLOGICAL: Pegfilgrastim|OTHER: Pharmacological Study|DRUG: Prednisone|BIOLOGICAL: Rituximab|DRUG: Vincristine Sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Protein-bound Toxin Removal Between Limited Blood Flow Super High-flux Online HDF and High-Efficiency Online HDF
Status: COMPLETED
Conditions: End-stage Renal Disease|Hemodialysis
Interventions: PROCEDURE: Limited BF OL-HDF with SHF|PROCEDURE: High-efficiency OL-HDF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect and Safety of Liraglutide 3.0 mg in Subjects With Overweight or Obesity and Type 2 Diabetes Mellitus Treated With Basal Insulin
Status: COMPLETED
Conditions: Metabolism and Nutrition Disorder|Obesity
Interventions: DRUG: Liraglutide 3.0 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Immediate-Release Oxycodone Capsules Study in Cancer Pain
Status: COMPLETED
Conditions: Cancer
Interventions: DRUG: Oxycodone|DRUG: Morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Prospective Study on the Treatment of cLM Based on ICG Imaging
Status: RECRUITING
Conditions: Lymphatic Malformation
Interventions: PROCEDURE: Inflow occlusion with perforation of septation and sclerotherapy|PROCEDURE: Perforation of septation and sclerotherapy|PROCEDURE: Indocyanine green-guided partial resection and sclerotherapy|PROCEDURE: Partial resection and sclerotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Outcomes of Laparoscopic Sleeve Gastrectomy
Status: COMPLETED
Conditions: Bariatric Surgery Candidate|Laparoscopic Sleeve Gastrectomy|Obesity, Morbid
Interventions: PROCEDURE: Laparoscopic sleeve gastrectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Care Expansion Across Remote Environments - Sub-Study of the SELF-GYN1 Trial
Status: WITHDRAWN
Conditions: Fertility Risk
Interventions: OTHER: Subsidy for fertility consult|OTHER: Invitation to purchase fertility consult
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Clinical Study Phase II of L19IL2 in Combination With Dacarbazine in Patients With Metastatic Melanoma
Status: TERMINATED
Conditions: Metastatic Melanoma
Interventions: DRUG: Arm 1: L19IL2 + Dacarbazine|DRUG: Arm 3: Dacarbazine|DRUG: ARM 2: L19IL2 + Dacarbazine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of (Licochalcone A) and Paclitaxel on Human Oral Squamous Cell Carcinoma Cell Line
Status: COMPLETED
Conditions: Squamous Cell Carcinoma
Interventions: DIETARY_SUPPLEMENT: Licochalcone A|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Pregnane X Receptor (PXR) Activation on Human Glucose, Lipid and Hormone Homeostasis
Status: COMPLETED
Conditions: Glucose Metabolism
Interventions: DRUG: Rifampicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Guided Biofilm Therapy for Periodontal Patients.
Status: COMPLETED
Conditions: Periodontal Diseases
Interventions: OTHER: Split-mouth administration for group B|OTHER: Split-mouth administration for group A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Theta-Burst Transcranial Magnetic Stimulation (TBS) for Early Alzheimer's Disease
Status: COMPLETED
Conditions: Transcranial Magnetic Stimulation|Magnetic Resonance Imaging|Alzheimer Disease
Interventions: OTHER: transcranial magnetic stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Remote Ischemic Pre-conditioning in Subarachnoid Hemorrhage
Status: COMPLETED
Conditions: Brain Aneurysms
Interventions: OTHER: Remote Ischemic Pre-conditioning|OTHER: Sham RIPC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Integrated Care for Patients With High Risk Substance Use and Psychiatric Disorder With Chronic Direct Acting Antiviral Treatment
Status: COMPLETED
Conditions: Hepatitis C|Depression|PTSD|Substance Use Disorder|Fibrosis
Interventions: BEHAVIORAL: Brief mental health interventions and case management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Tivantinib in Treating Patients With Recurrent or Metastatic Breast Cancer
Status: COMPLETED
Conditions: Estrogen Receptor Negative|HER2/Neu Negative|Progesterone Receptor Negative|Recurrent Breast Carcinoma|Stage IV Breast Cancer|Triple-Negative Breast Carcinoma
Interventions: OTHER: Laboratory Biomarker Analysis|DRUG: Tivantinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Buventol Easyhaler and Bufomix Easyhaler in Methacoline Challenge Testing
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Buventol® Easyhaler® 200 µg/inhalation dmDPI|DRUG: Bufomix® Easyhaler® 160/4.5 µg/inhalation dmDPI|DRUG: Ventoline® Evohaler® 100 µg/inhalation pMDI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Exercise Program for Facedown Posture-related Pain After Retinal Surgery
Status: COMPLETED
Conditions: Macular Holes|Retinal Detachment
Interventions: BEHAVIORAL: A structured exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Nutrition and Obesity in Under-Represented Populations: Food Insecurity Research to Advance Science and Improve Health
Status: RECRUITING
Conditions: Pediatric Obesity|Food Insecurity|Nutrition, Healthy|Nutrition Poor
Interventions: BEHAVIORAL: Grocery intervention - unrestricted|BEHAVIORAL: Grocery intervention - restricted
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Granisetron 1 mg Tablets, Non-fasting
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Granisetron hydrochloride 1 mg tablets|DRUG: Kytril® 1 mg tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Adebrelimab Combined With Chemotherapy for Neoadjuvant Therapy in Resectable Pancreatic Cancer
Status: RECRUITING
Conditions: Pancreatic Cancer|Neoadjuvant Therapy
Interventions: DRUG: Adebrelimab|DRUG: albumin-bound paclitaxel|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sunitinib Malate in Treating Patients With Previously Untreated Metastatic Kidney Cancer
Status: COMPLETED
Conditions: Clear Cell Renal Cell Carcinoma|Stage IV Renal Cell Cancer
Interventions: DRUG: sunitinib malate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety of Lactobacillus Reuteri in Healthy Children Ages 2 to 5 Years in Peru
Status: COMPLETED
Conditions: Healthy
Interventions: BIOLOGICAL: Lactobacillus reuteri|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: JVRS-100 for the Treatment of Patients With Relapsed or Refractory Leukemia
Status: COMPLETED
Conditions: Leukemia
Interventions: DRUG: JVRS-100|DRUG: JVRS-100
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Effectiveness and Safety Study of AQUAVAN® Injection (Fospropofol Disodium) for Sedation During Flexible Bronchoscopy
Status: COMPLETED
Conditions: Bronchoscopy|Anesthesia
Interventions: DRUG: AQUAVAN® (fospropofol disodium) Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Investigating the Effects of Dietary Phospholipids on Stress Reactivity and Recovery
Status: RECRUITING
Conditions: Mood|Stress|Physiological Stress
Interventions: DIETARY_SUPPLEMENT: Active|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Randomized Cross Over Trial of Two Treatments for Sleep Apnea in Veterans With Post-Traumatic Stress Disorder
Status: COMPLETED
Conditions: Obstructive Sleep Apnea
Interventions: DEVICE: CPAP|DEVICE: MAD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Deep Brain Stimulation (DBS) for Treatment Resistant Bipolar Disorder
Status: WITHDRAWN
Conditions: Bipolar Disorder
Interventions: DEVICE: DBS Activa PC systems Medtronic|DEVICE: DBS, Activa PC systems Medtronic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Congenital Cytomegalovirus: Efficacy of Antiviral Treatment
Status: COMPLETED
Conditions: Congenital Cytomegalovirus Infection|Sensorineural Hearing Loss
Interventions: DRUG: Valganciclovir
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Yerba Mate (Ilex Paraguariensis A.St.-Hil.): Assessment of Cardiovascular Health
Status: COMPLETED
Conditions: Cardiovascular Disease|Diabetes
Interventions: OTHER: Yerba Mate Extract|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: CCRC: Understanding the Effects of Omega-3 Fatty Acids Versus Lignans in Flaxseed on Metabolic and Inflammatory Markers Leading to Diabetes and Cardiovascular Disease
Status: COMPLETED
Conditions: Body Weight|Lipids|Blood Glucose|Insulin
Interventions: DIETARY_SUPPLEMENT: Flaxseed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Study Of Gemcitabine, Nab-paclitaxel, PEGPH20 and Rivaroxaban for Advanced Pancreatic Adenocarcinoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Pancreatic Cancer|Advanced Pancreatic Ductal Adenocarcinoma
Interventions: DRUG: Gemcitabine|DRUG: Nab-paclitaxel|DRUG: PEGPH20
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Drug Levels of CC-92480 After Coadministration With Rifampin and Itraconazole, and the Drug Levels of Digoxin and Rosuvastatin After Coadministration With CC-92480 in Healthy Participants
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: CC-92480|DRUG: Rifampin|DRUG: Itraconazole|DRUG: Digoxin|DRUG: Rosuvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of a Dyadic Cancer-related Communication Reinforcement Intervention
Status: COMPLETED
Conditions: Cancer|Communication Programs
Interventions: BEHAVIORAL: Dyadic Communication Reinforcement Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Nuts vs. a Wheat Bran Muffin in Type 2 Diabetes
Status: UNKNOWN
Conditions: Type 2 Diabetes|Cardiovascular Disease|Diet Therapy
Interventions: DIETARY_SUPPLEMENT: Whole wheat and bran muffin|DIETARY_SUPPLEMENT: Mixed tree nuts
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of External Oblique Intercostal Block in Laparoscopic Bariatric Surgery
Status: COMPLETED
Conditions: Bariatric Surgery Candidate|Pain, Postoperative|Narcotic Use|Analgesia
Interventions: OTHER: External oblique intercostal block|OTHER: Oblique subcostal TAP block|OTHER: Posterior Rectus sheath block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Dose-ranging Study of SPL7013 Gel for the Prevention of Bacterial Vaginosis (BV)
Status: COMPLETED
Conditions: Recurrent Bacterial Vaginosis (BV)
Interventions: DRUG: 1% SPL7013 Gel|DRUG: 3% SPL7013 Gel|DRUG: placebo gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of AMNN107 in the Treatment of Metastatic and/or Inoperable Melanoma Harboring a c-Kit Mutation
Status: COMPLETED
Conditions: Melanoma
Interventions: DRUG: Nilotinib|DRUG: DTIC
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparison of LY686017 With a Marketed Drug in the Treatment of Social Anxiety Disorder
Status: COMPLETED
Conditions: Social Phobia
Interventions: DRUG: LY686017|DRUG: paroxetine|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: To Demonstrate the Relative Bioavailability of Desipramine Hydrochloride Tablets
Status: COMPLETED
Conditions: Depression
Interventions: DRUG: Desipramine Hydrochloride 100 mg Tablets (Cord Laboratories)|DRUG: Norpramin 100 mg Tablets (Merrell Dow Pharmaceuticals, Inc.)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tolerability and Immunogenicity of Gardasil in Females Between 16 and 23 Years of Age in India (V501-034)
Status: SUSPENDED
Conditions: HPV Infections
Interventions: BIOLOGICAL: Quadrivalent Human Papillomavirus (Types 6, 11, 16, 18) Recombinant Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Immunotherapy for Advanced Liver Cancer
Status: RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: BIOLOGICAL: AlloStim® immunotherapy|DRUG: FOLFOX regimen|DRUG: Sorafenib|DRUG: Lenvatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Microwave Diathermy for Treating Nonspecific Chronic Neck Pain
Status: COMPLETED
Conditions: Neck Pain
Interventions: RADIATION: Continuous microwave|RADIATION: Pulsed microwaves|PROCEDURE: Sham microwaves
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics of Sublingual Versus Oral Tacrolimus in Patients Awaiting Kidney Transplantation
Status: COMPLETED
Conditions: Kidney Failure, Chronic
Interventions: DRUG: Tacrolimus (Arm B)|DRUG: Clotrimazole Troche|DRUG: Tacrolimus (Arm A)|DRUG: Nystatin Suspension
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Efficacy and Safety of 26-Week Treatment of AR1001 in Patients With Mild to Moderate Alzheimer's Disease
Status: COMPLETED
Conditions: Mild to Moderate Alzheimer's Disease
Interventions: DRUG: AR1001|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Effectiveness of BioTraceIO 360 for Planning, Monitoring and Assessment of Liver Tissue Ablation Procedures (PANORAMA2)
Status: WITHDRAWN
Conditions: Hepatocellular Carcinoma|Metastatic Liver Cancer
Interventions: DEVICE: BioTraceIO 360
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Efficacy and Safety of the Use of Venocur Triplex® in Patients With Chronic Venous Insufficiency
Status: COMPLETED
Conditions: Venous Insufficiency
Interventions: DRUG: Venocur Triplex®|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of CC-4047 (Pomalidomide) to Treat Advanced Soft Tissue Sarcoma
Status: TERMINATED
Conditions: Soft Tissue Sarcoma
Interventions: DRUG: Pomalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dual Transversus Abdominis Plane Block in Pediatric Renal Transplant: Effect on Pain Control
Status: COMPLETED
Conditions: Renal Failure
Interventions: DRUG: bupivacaine|DRUG: Pethidine|DRUG: perfalgan|DRUG: fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Propranolol Reactivation Mismatch (PRM) Treatment for PTSD
Status: UNKNOWN
Conditions: Stress Disorders, Post-Traumatic
Interventions: DRUG: Reactivation Mismatch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SAD and MAD Study to Evaluate Safety, Tolerability, and Pharmacokinetics (PK) of TD-1473 in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: TD-1473 for SAD|DRUG: Placebo for SAD|DRUG: TD-1473 for MAD|DRUG: Placebo for MAD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Anesthetic Techniques in EP Patients
Status: TERMINATED
Conditions: Cardiac Disease
Interventions: DRUG: Propofol|DRUG: Ketamine|DRUG: Remifentanil|DRUG: Sevoflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: OTHER
Clinical trial: Multicenter, Open-Label, Randomised, Haloperidol-controlled Study to Evaluate Seroquel as Mono-Therapy in the Treatment of Agitated Symptoms in the Patients With Acute Episode of Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Quatiapine Fumarate|DRUG: Haloperidol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Yttrium-90 Radioactive Resin Microspheres to Treat Colorectal Adenocarcinoma Metastatic to the Liver
Status: TERMINATED
Conditions: Colorectal Neoplasms|Liver Neoplasms
Interventions: DEVICE: Yttrium-90 Radioactive Resin Microspheres
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of a Home Test for Gluten Detection in Urine and Its Effect on Gluten-free Diet Adherence
Status: SUSPENDED
Conditions: Celiac Disease|Treatment Adherence|Adolescent
Interventions: DIAGNOSTIC_TEST: GlutenDetect home urine test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: In Vivo Assessment of the Tooth-Resin Composite Interface Using Optical Coherence Tomography
Status: ACTIVE_NOT_RECRUITING
Conditions: Cavity|Cavities of Teeth
Interventions: DEVICE: Composite with 90 degree cavosurface angle|DEVICE: Composite with wide bevel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of the Effectiveness of Different Types of Exercise for People With Knee Osteoarthritis
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: OTHER: Kinesthesia, Balance, and Agility (KBA) Exercise|OTHER: Standard LE Strength Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy of Losartan + Amlodipine Compared to Amlodipine Alone in the Treatment of Uncontrolled High Blood Pressure (MK-0954F-399)
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Losartan (+) amlodipine|DRUG: Placebo to match losartan/amlodipine tablets|DRUG: Amlodipine camsylate|DRUG: Placebo to match amlodipine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Wired Mothers - Use of Mobile Phones to Improve Maternal and Neonatal Health in Zanzibar
Status: COMPLETED
Conditions: Pregnancy|Maternal Health|Newborn Death|Health Behavior|mHealth
Interventions: DEVICE: Wired mothers
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Double-blind, Intra-individual Comparison, POC Trial of AC-203 in EB Patients
Status: COMPLETED
Conditions: Inherited Epidermolysis Bullosa
Interventions: DRUG: AC-203|DRUG: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: T-cell And General Immune Response to Seasonal Influenza Vaccine (SLVP018) Year 3, 2011
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: TIV|BIOLOGICAL: High-Dose TIV
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Usefulness of Biatrial 3D Printing to Plan Transseptal Puncture for the Left Atrial Appendage Closure
Status: RECRUITING
Conditions: Atrial Fibrillation|Left Atrial Appendage Closure
Interventions: DEVICE: Left atrial appendage closure
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Evaluation of a Nasal Mask for the Treatment of Obstructive Sleep Apnea (OSA): Comfort & Performance Trial
Status: COMPLETED
Conditions: Sleep Disordered Breathing|Obstructive Sleep Apnea
Interventions: DEVICE: Saturn nasal mask
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Comparing Lutonix AV Drug Coated Balloon vs Standard Balloon for Treatment of Dysfunctional AV Fistulae
Status: COMPLETED
Conditions: Arteriovenous Fistula
Interventions: COMBINATION_PRODUCT: Lutonix DCB|DEVICE: Standard Balloon Angioplasty Catheter|PROCEDURE: Percutaneous Transluminal Angiography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: EZ Blocker Versus Left Sided Double-lumen Tube
Status: COMPLETED
Conditions: One-lung Ventilation
Interventions: DEVICE: Placement of double lumen tube for one-lung ventilation|DEVICE: Placement of EZ- Blocker for one-lung ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Impact of the COVID-19 Pandemic and HRQOL in Cancer Patients and Survivors
Status: ACTIVE_NOT_RECRUITING
Conditions: COVID-19 Infection|Malignant Solid Neoplasm
Interventions: OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration|OTHER: Survey Administration
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Gemcitabine/Oxaliplatin (GEMOX) With or Without Erlotinib (Tarceva) in Advanced Biliary Tract Carcinoma
Status: COMPLETED
Conditions: Unresectable, Metastatic Biliary Tract Carcinoma
Interventions: DRUG: Gemcitabine/Oxaliplatin|DRUG: Gemcitabine/Oxaliplatin with Erlotinib (Tarceva)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nutrition to Relieve IBS Symptoms by Targeting the Microbiota
Status: COMPLETED
Conditions: Irritable Bowel Syndrome
Interventions: DIETARY_SUPPLEMENT: Dietary fiber supplement|DIETARY_SUPPLEMENT: Caseine protein hydrolisate|DIETARY_SUPPLEMENT: Maltrodextrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Βeta-adrenoceptor Inverse Agonist and Biased Ligand, Nadolol, In Smoking Cessation of Patients With Chronic Cough With or Without Airflow Obstruction
Status: COMPLETED
Conditions: Smoking Cessation
Interventions: DRUG: Nadolol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Open-Label Extension Study of MCS-2 in the Treatment of Lower Urinary Tract Symptoms (MCS-2-US-c)
Status: COMPLETED
Conditions: Lower Urinary Tract Symptoms|Benign Prostatic Hyperplasia
Interventions: DRUG: MCS-2
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Vitamin D and Uric Acid Lowering on Kidney and Blood Vessel Function
Status: COMPLETED
Conditions: Renal Function|Endothelial Function|Blood Pressure|Overweight|Obesity
Interventions: DRUG: Vitamin D ergocalciferol|DRUG: Probenecid|DRUG: Allopurinol|DRUG: Placebo|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study Investigating the Effects of Acetyl-L-Carnitine and Vincristine-Induced Neuropathy in Pediatric Patients With ALL
Status: TERMINATED
Conditions: Vincristine Induced Neuropathy
Interventions: DRUG: Acetylcarnitine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Human Models of Selective Insulin Resistance: Pancreatic Clamp
Status: NOT_YET_RECRUITING
Conditions: Insulin Resistance|Hyperinsulinemia|Metabolic Dysfunction Associated Steatotic Liver Disease|Non-Alcoholic Fatty Liver Disease|Prediabetic State|Obesity
Interventions: DRUG: Insulin human|DRUG: Octreotide Acetate|DRUG: Glucagon|DRUG: Growth Hormone, Human|DRUG: 20% D-glucose (aq)|DIAGNOSTIC_TEST: [6,6-2H2] D-glucose|DIAGNOSTIC_TEST: [1-13C1] sodium acetate|DIETARY_SUPPLEMENT: Nestle BOOST Plus|DIETARY_SUPPLEMENT: KIND Bar|DEVICE: Harvard Apparatus PHD ULTRA CP syringe pump|DEVICE: Yellow Springs Instruments (YSI) 2500 Biochemistry Glucose/Lactate Analyzer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of the Long-term Safety, Tolerability, and Efficacy of Perampanel (E2007) as an Adjunctive Therapy in Levodopa Treated Parkinson's Disease Subjects With Motor Fluctuations
Status: TERMINATED
Conditions: Parkinson's Disease
Interventions: DRUG: Perampanel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Effects of Single Versus Triple Injections of Platelet-Rich Plasma in Patients With Knee Osteoarthritis
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: OTHER: prp injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Fecal Incontinence by Injection of Autologous Muscle Fibers Into the Anal Sphincter
Status: UNKNOWN
Conditions: Fecal Incontinence|Anal Incontinence
Interventions: PROCEDURE: Injection of autologous muscle fibers into the anal sphincter.|PROCEDURE: Pelvic floor muscle training|BEHAVIORAL: Dietary intervention|DRUG: Analgesia
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Dry Eye Disease's Signs in Patients Who Were Administered Intravitreal Anti-VEGF Injections
Status: RECRUITING
Conditions: Dry Eye Syndromes
Interventions: DEVICE: Thealoz Duo;|DEVICE: sham (Hydrabak)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy in Treating Patients With Primary Peritoneal or Stage III Epithelial Ovarian Cancer
Status: COMPLETED
Conditions: Ovarian Cancer|Primary Peritoneal Cavity Cancer
Interventions: DRUG: cisplatin|DRUG: paclitaxel|PROCEDURE: quality-of-life assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Smart Start: A Phase II Study of Rituximab, Lenalidomide, and Ibrutinib
Status: COMPLETED
Conditions: Diffuse Large B-Cell Lymphoma Unclassifiable
Interventions: DRUG: Cyclophosphamide|DRUG: Doxorubicin Hydrochloride|DRUG: Etoposide|DRUG: Ibrutinib|DRUG: Lenalidomide|DRUG: Prednisone|BIOLOGICAL: Rituximab|DRUG: Vincristine Sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Problem-Solving Therapy for Cancer Caregivers in Outpatient Palliative Care
Status: ENROLLING_BY_INVITATION
Conditions: Depression, Anxiety|Palliative Care|Caregivers|Cancer
Interventions: BEHAVIORAL: Problem-Solving Therapy|OTHER: Attention-matched Control|OTHER: In-depth interviews
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Light and the Effect on Metabolic Syndrome and Alzheimer's Disease
Status: RECRUITING
Conditions: Alzheimer Disease|Diabetes Mellitus, Type 2
Interventions: DEVICE: Tailored Lighting Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Weight Loss Aid in an Exposed Population
Status: COMPLETED
Conditions: Polybrominated Biphenyl Poisoning
Interventions: DRUG: Orlistat|DRUG: Placebo capsule|DIETARY_SUPPLEMENT: Multivitamin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT