pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Efficacy of TOCT and (tDCS) for Gait Improvement in Patients With Chronic Stroke
Status: COMPLETED
Conditions: Stroke
Interventions: DEVICE: sham tDCS + TOCT|DEVICE: real tDCS + TOCT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Rosmarinus Officinalis Versus 2.5%Sodium Hypochlorite as Root Canal Irrigants
Status: UNKNOWN
Conditions: Necrotic Pulp
Interventions: OTHER: Rosmarinus Officinallis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial to Evaluate the Effect of Esomeprazole on the Pharmacokinetics of Emraclidine in Healthy Adult Participants
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DRUG: Emraclidine|DRUG: Esomeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Yoga on the Quality of Life of Breast Cancer Patients
Status: RECRUITING
Conditions: Breast Neoplasms|Cancer
Interventions: BEHAVIORAL: Iyengar Yoga|BEHAVIORAL: Meditative Yoga
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study Evaluating the Efficacy of Fluocinonide Cream 0.1% (Vanos) in Subjects With Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: Fluocinonide Cream 0.1%
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of High Flow Nasal Cannula (HFNC), Face-mask Non-Invasive Ventilation (NIV) & Helmet NIV in COVID-19 ARDS Patients
Status: TERMINATED
Conditions: Acute Respiratory Distress Syndrome Caused by COVID-19
Interventions: DEVICE: High flow nasal cannula (HFNC)|DEVICE: Helmet NIV|DEVICE: Face-mask NIV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Indigotindisulfonate Sodium Injection, USP as an Aid in the Determination of Ureteral Patency in Pediatric Patients
Status: NOT_YET_RECRUITING
Conditions: Ureter Injury
Interventions: DRUG: Indigotindisulfonate sodium 0.8% injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Mindfulness Exercises to Reduce Anxiety and Pain During Urodynamic Testing
Status: COMPLETED
Conditions: Stress Incontinence, Female|Overactive Bladder|Lower Urinary Tract Symptoms
Interventions: BEHAVIORAL: Mindfulness exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of the Use of an mHealth Intervention on Quality of Care
Status: COMPLETED
Conditions: Malaria|Diarrhea|Acute Respiratory Infection
Interventions: OTHER: mHealth Intervention for Quality of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Patient Safety Learning Laboratory: Making Acute Care More Patient-Centered
Status: COMPLETED
Conditions: Central Line-Associated Bloodstream Infection (CLABSI)|Venous Thromboembolism|Patient Fall|Catheter-Associated Infection|Severe Hypoglycemia|Opioid-Related Severe Adverse Drug Event|Hospital Acquired Pressure Ulcer|Adverse Drug Event|Severe Hospital Acquired Delerium|Rapid Response Related to Arrhythmia
Interventions: BEHAVIORAL: Patient Safety health information technology
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Buprenorphine vs Buprenorphine/Naloxone on the Effects of Maternal Symptomatology
Status: WITHDRAWN
Conditions: Opioid-use Disorder
Interventions: DRUG: Buprenorphine/naloxone|DRUG: Buprenorphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Bridging Trial to Compare the PK Profile When Glepaglutide is Administered Via Vial/Syringe Versus Autoinjector.
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Glepaglutide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Randomized Phase III Study of Folfiri+Avastin Versus Xeliri+Avastin as 1st Line Treatment of CRC
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: Irinotecan|DRUG: 5-Fluorouracil|DRUG: Leucovorin|DRUG: Capecitabine|DRUG: Bevacizumab|DRUG: Bevacizumab|DRUG: Irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Modified Nab-Paclitaxel Plus Gemcitabine Chemotherapy for Metastatic Pancreatic Cancer
Status: UNKNOWN
Conditions: Metastatic Pancreatic Cancer
Interventions: DRUG: Modified Gemcitabine plus nab-Paclitaxel Combination Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GDC-0449 in Treating Patients With Recurrent Glioblastoma Multiforme That Can Be Removed by Surgery
Status: COMPLETED
Conditions: Adult Giant Cell Glioblastoma|Adult Glioblastoma|Adult Gliosarcoma|Recurrent Adult Brain Tumor
Interventions: DRUG: vismodegib|PROCEDURE: therapeutic conventional surgery|OTHER: laboratory biomarker analysis|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exploratory Study of IFX-1 in Patients With Pyoderma Gangrenosum
Status: COMPLETED
Conditions: Pyoderma Gangrenosum
Interventions: DRUG: vilobelimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Potential Effect of Benralizumab on the Humoral Immune Response to the Seasonal Influenza Vaccination in Adolescent and Young Adult Patients With Severe Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Benralizumab|DRUG: Benralizumab Placebo|DRUG: Seasonal influenza virus vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Combination of Irreversible Electroporation and NK Immunotherapy for Recurrent Liver Cancer
Status: COMPLETED
Conditions: Recurrent Liver Carcinoma
Interventions: DEVICE: Irreversible Electroporation|BIOLOGICAL: Natural killer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: PEITHO Pulmonary Embolism Thrombolysis Study
Status: COMPLETED
Conditions: Pulmonary Embolism
Interventions: DRUG: placebo ( group B)|DRUG: tenecteplase (group A)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Safety, Tolerance and Efficacy of ASC22 Combined With ART in Subjects With HIV
Status: RECRUITING
Conditions: HIV-1-infection|HIV Infections|PD-L1 Gene Mutation
Interventions: DRUG: ASC22 1mg/kg|DRUG: ASC22 2.5mg/kg|DRUG: Antiretroviral Therapy|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Atomoxetine for Treating Cocaine Abuse in Adults With Attention Deficit Hyperactivity Disorder (ADHD)
Status: COMPLETED
Conditions: Attention Deficit Disorder With Hyperactivity|Cocaine-Related Disorders
Interventions: DRUG: Atomoxetine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Personalized Vaccine in Treating Patients With Smoldering Multiple Myeloma
Status: ACTIVE_NOT_RECRUITING
Conditions: Smoldering Plasma Cell Myeloma
Interventions: PROCEDURE: Biopsy Specimen Radiography|DRUG: Lenalidomide|BIOLOGICAL: Vaccine Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dinutuximab in Combination With Sargramostim in Treating Patients With Recurrent Osteosarcoma
Status: COMPLETED
Conditions: Metastatic Malignant Neoplasm in the Lung|Metastatic Osteosarcoma|Recurrent Osteosarcoma
Interventions: BIOLOGICAL: Dinutuximab|OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacological Study|BIOLOGICAL: Sargramostim
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Claudication: Exercise Versus Endoluminal Revascularization (CLEVER)
Status: UNKNOWN
Conditions: Cardiovascular Diseases|Peripheral Vascular Diseases|Atherosclerosis
Interventions: DEVICE: Stent|BEHAVIORAL: Supervised Exercise Therapy|DRUG: Cilostazol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Predictive Score of PneumOThorax Secondary to CT-guided Transthoracic Lung Biopsy Made From a Large Retrospective Cohort and Validated on a Prospective Cohort
Status: UNKNOWN
Conditions: Pneumothorax
Interventions: PROCEDURE: Needle lung biopsy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Assess the Potential for Pre-systemic Inhibition of CYP3A by Idebenone Using Midazolam as a Substrate
Status: COMPLETED
Conditions: Drug-Drug Interaction
Interventions: DRUG: Raxone (idebenone 150 mg)|DRUG: Midazolam 2,5 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: STI571 Compared With Interferon Alfa Plus Cytarabine in Treating Patients With Newly Diagnosed Chronic Myelogenous Leukemia
Status: COMPLETED
Conditions: Leukemia
Interventions: BIOLOGICAL: recombinant interferon alfa|DRUG: cytarabine|DRUG: imatinib mesylate
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Radiographic and the Esthetic Outcome of Two Different Bone Grafting Techniques in Early Implant Placement
Status: COMPLETED
Conditions: Missing Tooth|Fractured Tooth
Interventions: PROCEDURE: Guided bone regeneration with Bovine Bone Mineral|PROCEDURE: Guided bone regeneration with freeze dried bone allograft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Pyrotinib in HER2 Positive Gastrointestinal Tumors
Status: UNKNOWN
Conditions: Gastrointestinal Tumor|Effect of Drug
Interventions: DRUG: Pyrotinib with or without trastuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Viburnum Opulus 3X in the Treatment of Primary Dysmenorrhea
Status: COMPLETED
Conditions: Dysmenorrhea
Interventions: OTHER: 20% Ethanol|OTHER: Viburnum opulus 3X
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Home-based tDCS for Apathy in Alzheimer's Disease
Status: TERMINATED
Conditions: Alzheimer Disease and Related Dementias
Interventions: DEVICE: home-based active tDCS|DEVICE: home-based sham tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Olaparib in Pretreated Patients With Measurable Colorectal Cancer, Stratified by Microsatellite Instability (MSI) Status
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: olaparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of VR Distraction During Local Anesthesia in Children
Status: COMPLETED
Conditions: Virtual Reality|Anesthesia, Local|Pain
Interventions: DEVICE: active distraction|DEVICE: passive distraction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Analgesic Efficacy of Intrathecal Fentanyl-Morphine Combination Versus Morphine Alone for Intraoperative Pain During Elective Cesarean Delivery
Status: NOT_YET_RECRUITING
Conditions: Intraoperative Pain
Interventions: DRUG: Fentanyl-Morphine|DRUG: Morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Myoinositol, L-arginine and Chromium With Letrozole for Ovulation Induction in Polycystic Ovarian Syndrome Patients
Status: NOT_YET_RECRUITING
Conditions: Polycystic Ovary Syndrome
Interventions: DRUG: Myoinositol|DRUG: Chromium|DRUG: l-arginine|DRUG: Letrozole 2.5mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Direct Superior Approach Versus PosteroLateral Approach in Total Hip Arthroplasty (SPLAsH)
Status: RECRUITING
Conditions: Osteoarthritis, Hip
Interventions: PROCEDURE: Total Hip Arthroplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Approved Pacing Lead (Model 5076) for Use in MRI Environment
Status: COMPLETED
Conditions: Magnetic Resonance Imaging (MRI)|Cardiac Pacing
Interventions: OTHER: Magnetic Resonance Imaging scan sequences of the head, neck, and chest|DEVICE: Pacemaker System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Effect of Pulmonary Recruitment Maneuver (PRM) on Pain and Nausea After Laparoscopic Cholecystectomy
Status: COMPLETED
Conditions: Pain, Postoperative|Postoperative Nausea and Vomiting
Interventions: PROCEDURE: Pulmonary Recruitment Maneuver|PROCEDURE: Laparoscopic cholecystectomy|DEVICE: Ventilator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Whole-Abdominal Radiation Therapy and Cisplatin in Treating Patients With Stage III or Stage IV Endometrial Cancer That Has Been Removed by Surgery
Status: COMPLETED
Conditions: Endometrial Cancer
Interventions: RADIATION: Vaginal Brachytherapy|DRUG: Cisplatin|RADIATION: Whole Abdominal Radiation [WAR] Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: p53 Suppressor Activation in Recurrent High Grade Serous Ovarian Cancer, a Phase Ib/II Study of Systemic Carboplatin Combination Chemotherapy With or Without APR-246
Status: COMPLETED
Conditions: Platinum Sensitive Recurrent High-grade Serous Ovarian Cancer With Mutated p53
Interventions: DRUG: APR-246|DRUG: Carboplatin and Pegylated Liposomal Doxorubicin Hydrochloride (PLD)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tenofovir Versus Lamivudine for Patients of Chronic Hepatitis B With Severe Acute Exacerbation
Status: UNKNOWN
Conditions: Chronic HBV With Severe Exacerbation
Interventions: DRUG: Tenofovir|DRUG: lamivudine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Protein Intake on Muscle Protein Synthesis Overnight
Status: COMPLETED
Conditions: Protein Synthesis Overnight
Interventions: DIETARY_SUPPLEMENT: Milk protein|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: P.E.M.F. Therapy of Chronic Wounds
Status: NOT_YET_RECRUITING
Conditions: Chronic Wounds
Interventions: DEVICE: Pulsed ElectroMagnetic Field (PEMF) therapy|OTHER: Pulsed ElectroMagnetic (PEMF) therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Lenalidomide and Combination Chemotherapy in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia
Status: TERMINATED
Conditions: Adult Acute Megakaryoblastic Leukemia (M7)|Adult Acute Minimally Differentiated Myeloid Leukemia (M0)|Adult Acute Monoblastic Leukemia (M5a)|Adult Acute Monocytic Leukemia (M5b)|Adult Acute Myeloblastic Leukemia With Maturation (M2)|Adult Acute Myeloblastic Leukemia Without Maturation (M1)|Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities|Adult Acute Myeloid Leukemia With Del(5q)|Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)|Adult Acute Myeloid Leukemia With t(16;16)(p13;q22)|Adult Acute Myeloid Leukemia With t(8;21)(q22;q22)|Adult Acute Myelomonocytic Leukemia (M4)|Adult Erythroleukemia (M6a)|Adult Pure Erythroid Leukemia (M6b)|Recurrent Adult Acute Myeloid Leukemia
Interventions: DRUG: lenalidomide|DRUG: mitoxantrone hydrochloride|DRUG: etoposide|DRUG: cytarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ocytocine and Cerebral Activation in Relation With Attachement
Status: COMPLETED
Conditions: Attachement Style
Interventions: DRUG: nasal oxytocin or placebo|DEVICE: fMRI|BEHAVIORAL: Attachement scale interview (ASI)|BEHAVIORAL: psychometric scales
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Preservation of Swallowing in Respected Oral Cavity Squamous Cell Carcinoma: Examining Radiation Volume Effects (PRESERVE): A Randomized Trial
Status: RECRUITING
Conditions: Head and Neck Cancer
Interventions: RADIATION: Radiotherapy to all dissected areas|RADIATION: Omit radiation to pN0 neck
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Safety, Pharmacokinetics, and Antitumor Activity of BGB-3245 in Participants With Advanced or Refractory Tumors
Status: RECRUITING
Conditions: Solid Tumor|B-Raf Mutation-Related Tumors
Interventions: DRUG: BGB-3245
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating Safety and Tolerability of Ascending Multiple Dose of SLV-313 in Schizophrenia Patients
Status: TERMINATED
Conditions: Healthy
Interventions: DRUG: SLV-313 SR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy vs Placebo as Initial Combination Therapy With Pioglitazone
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: placebo + pioglitazone (30 mg)|DRUG: Linagliptin + pioglitazone (30 mg)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: proMoting Effective Renoprotection in Cardiac sURgery Patients by Inhibition of SGLT-2
Status: RECRUITING
Conditions: Acute Kidney Injury|Cardiac Surgery|Sodium-Glucose Transporter 2 Inhibitor
Interventions: DRUG: Dapagliflozin 10 MG Oral Tablet [Farxiga]|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Prevention of Progression of Duodenal Adenomas in Patients With Familial Adenomatous Polyposis
Status: COMPLETED
Conditions: Familial Adenomatous Polyposis|Duodenal Neoplasms|Duodenal Polyps
Interventions: DRUG: Celecoxib|DRUG: Ursodeoxycholic acid|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Black Health Block Quit and Screen Project
Status: NOT_YET_RECRUITING
Conditions: Knowledge|Attitudes|Behavioral Intention
Interventions: OTHER: Black Health Block Culturally Tailored training|OTHER: Health Disparities and Lung Cancer Screening training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Adapting and Adopting Highly Specialized Pediatric Eating Disorder Treatment to Virtual Care: Implementation Research for the COVID-19 Context and Beyond
Status: COMPLETED
Conditions: Anorexia Nervosa
Interventions: BEHAVIORAL: Virtual Family-Based Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of 10 cm Catheter Mount on Malfunction of Capnometers Under the Conditions of Water
Status: COMPLETED
Conditions: Cardiopulmonary Resuscitation|Pulmonary Edema|Hemorrhage
Interventions: DEVICE: No-DCCM|DEVICE: DCCM|OTHER: Water 5ml in tracheal tube|OTHER: Water 10ml in tracheal tube
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of a Compound With Pilocarpine and Brimonidine to Improve Near Vision in Healthy Presbyopic Patients
Status: UNKNOWN
Conditions: Presbyopia
Interventions: DRUG: Compound Pilocarpine, Brimonidine, Oxymetazoline, Hyaluronic acid, Bromfenac|DRUG: Pilocarpine Hydrochloride|DRUG: Brimonidine Tartrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Treatment With Regorafenib and Capecitabine Combined With Radiotherapy in Locally Advanced Rectal Cancer
Status: TERMINATED
Conditions: Rectal Cancer
Interventions: DRUG: Regorafenib|DRUG: Capecitabine|RADIATION: Radiotherapy|PROCEDURE: Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Saliva Insulin as Biomarker of Risk Factors for Metabolic Dysregulation and Caries
Status: RECRUITING
Conditions: Caries|Metabolomic Profile
Interventions: OTHER: Drinking water|OTHER: Apple juice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pivotal Study of MRI-guided Transurethral Ultrasound Ablation in Patients With Localized Prostate Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Cancer
Interventions: DEVICE: MRI-guided Transurethral Ultrasound Ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Colony Stimulating Factor on Poor Endometrial Development During IVF
Status: TERMINATED
Conditions: Infertility, Female
Interventions: DRUG: G-CSF|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: IV Gallium Study for Patients With Cystic Fibrosis Who Have NTM (ABATE Study)
Status: RECRUITING
Conditions: Nontuberculous Mycobacterium Infection
Interventions: DRUG: Gallium nitrate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ameliorative Potential of Relaxing Back Massage on Puerperial Women's Hormones and Infant Weight
Status: COMPLETED
Conditions: Does Postpartum Massage Affect Leptin, Prolactin and Growth Hormone
Interventions: OTHER: Postpartum back massage in study group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study to Assess the Efficacy and Safety of Enzalutamide in Subjects With Advanced Hepatocellular Carcinoma
Status: COMPLETED
Conditions: Advanced Hepatocellular Carcinoma
Interventions: DRUG: Enzalutamide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Preventing Adolescents From Entering the Juvenile Justice System
Status: COMPLETED
Conditions: Substance Use|Delinquency
Interventions: BEHAVIORAL: CCP+MDFT|BEHAVIORAL: CCP+SAU
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Iron Fortified Wheat Flour on Cognition and Iron Status in Indian School Children
Status: COMPLETED
Conditions: Iron Deficiency|Iron Deficiency Anemia|Cognition
Interventions: OTHER: Fortification of wheat flour with NaFeEdta
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose:
Clinical trial: Myelodysplastic Syndrome--CDA-2 Hematological Improvement National Affirmation Study
Status: UNKNOWN
Conditions: Myelodysplastic Syndrome (MDS)
Interventions: DRUG: CDA-2 (Cell Differentiation Agent 2)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Program to Assess Adverse Events and Change in Disease Activity of Oral Upadacitinib in Adult Participants With Moderate to Severe Systemic Lupus Erythematosus
Status: RECRUITING
Conditions: Systemic Lupus Erythematosus
Interventions: DRUG: Upadacitinib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Triclosan Toothpaste and Third Molar Surgery
Status: COMPLETED
Conditions: Dry Socket|Wound Infection
Interventions: OTHER: Colgate Total Toothpaste|OTHER: Colgate Regular Toothpaste
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Ketogenic Diet vs Mixed Diet in Patients With Heart Failure
Status: RECRUITING
Conditions: Heart Failure With Preserved Ejection Fraction
Interventions: DIETARY_SUPPLEMENT: Ketogenic diet|DIETARY_SUPPLEMENT: Low-fat Mixed diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Paclitaxel Micelles for Injection / Paclitaxel Injection in Combination With Cisplatin for First-line Therapy of Advanced NSCLC
Status: UNKNOWN
Conditions: Non-Small Cell Lung Cancer(NSCLC)
Interventions: DRUG: Paclitaxel Micelles for Injection|DRUG: Paclitaxel Injection|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects on Neuromuscular Function After Dry Needling in Myofascial Trigger Points in the Gastrocnemius Muscles
Status: COMPLETED
Conditions: Myofascial Trigger Point Pain
Interventions: OTHER: Dry needling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Efficacy and Safety of Gimsilumab in Subjects With Lung Injury or Acute Respiratory Distress Syndrome Secondary to COVID-19 (BREATHE)
Status: COMPLETED
Conditions: COVID-19
Interventions: DRUG: Gimsilumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Detection of Urinary Stones on ULDCT With Deep-learning Image Reconstruction Algorithm
Status: ACTIVE_NOT_RECRUITING
Conditions: Urolithiasis|Urinary Tract Stones|Renal Colic|Deep Learning Reconstruction
Interventions: DIAGNOSTIC_TEST: Abdominopelvic low dose CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Role of Immune Semaphorins in Steatotic Liver Disease and Sepsis
Status: RECRUITING
Conditions: Steatosis of Liver|Sepsis|Immune Response
Interventions: DIAGNOSTIC_TEST: Evaluation of the degree of steatosis|DIAGNOSTIC_TEST: Screening for the components of metabolic syndrome|DIAGNOSTIC_TEST: Measurement of serum semaphorin concentrations|DIAGNOSTIC_TEST: Measurement of inflammatory cytokines
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: F-18 16 Alpha-Fluoroestradiol-Labeled Positron Emission Tomography in Predicting Response to First-Line Hormone Therapy in Patients With Stage IV Breast Cancer
Status: COMPLETED
Conditions: Estrogen Receptor-positive Breast Cancer|Progesterone Receptor-negative Breast Cancer|Progesterone Receptor-positive Breast Cancer|Recurrent Breast Cancer|Stage IV Breast Cancer
Interventions: RADIATION: F-18 16 alpha-fluoroestradiol|RADIATION: fludeoxyglucose F 18|PROCEDURE: positron emission tomography|PROCEDURE: positron emission tomography|PROCEDURE: computed tomography|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Food Effect on Pharmacokinetics and Safety of Fixed-dose Combination of CJ-30056 in Healthy Male Subjects
Status: COMPLETED
Conditions: Food Effect Study of CJ-30056 20mg/500mg
Interventions: DIETARY_SUPPLEMENT: CJ-30056 20/500mg (atorvastatin/metformin XR 20/500mg)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Monoclonal Antibody Therapy Before Stem Cell Transplant in Treating Patients With Relapsed or Refractory Lymphoid Malignancies
Status: TERMINATED
Conditions: Adult Nasal Type Extranodal NK/T-cell Lymphoma|Anaplastic Large Cell Lymphoma|Angioimmunoblastic T-cell Lymphoma|Cutaneous B-cell Non-Hodgkin Lymphoma|Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue|Hepatosplenic T-cell Lymphoma|Intraocular Lymphoma|Nodal Marginal Zone B-cell Lymphoma|Noncutaneous Extranodal Lymphoma|Peripheral T-cell Lymphoma|Recurrent Adult Burkitt Lymphoma|Recurrent Adult Diffuse Large Cell Lymphoma|Recurrent Adult Diffuse Mixed Cell Lymphoma|Recurrent Adult Diffuse Small Cleaved Cell Lymphoma|Recurrent Adult Grade III Lymphomatoid Granulomatosis|Recurrent Adult Hodgkin Lymphoma|Recurrent Adult Immunoblastic Large Cell Lymphoma|Recurrent Adult Lymphoblastic Lymphoma|Recurrent Adult T-cell Leukemia/Lymphoma|Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma|Recurrent Grade 1 Follicular Lymphoma|Recurrent Grade 2 Follicular Lymphoma|Recurrent Grade 3 Follicular Lymphoma|Recurrent Mantle Cell Lymphoma|Recurrent Marginal Zone Lymphoma|Recurrent Mycosis Fungoides/Sezary Syndrome|Recurrent Small Lymphocytic Lymphoma|Refractory Hairy Cell Leukemia|Small Intestine Lymphoma|Splenic Marginal Zone Lymphoma|T-cell Large Granular Lymphocyte Leukemia|Testicular Lymphoma|Waldenström Macroglobulinemia
Interventions: BIOLOGICAL: indium In 111 anti-CD45 monoclonal antibody BC8|RADIATION: yttrium Y 90 anti-CD45 monoclonal antibody BC8|PROCEDURE: peripheral blood stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ketone Esters for Appetite, Cognition, and Cardiovascular Function in Individuals With Obesity and Insulin Resistance
Status: COMPLETED
Conditions: Metabolic Syndrome
Interventions: DIETARY_SUPPLEMENT: Ketone Ester Supplement|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of GSK3772847 in Subjects With Moderately Severe Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: GSK3772847|DRUG: Placebo|DRUG: Fluticasone propionate/salmeterol|DRUG: Fluticasone propionate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Probiotics on Weight Control and Body Composition in Overweight and Obese Individuals
Status: COMPLETED
Conditions: Obesity
Interventions: DIETARY_SUPPLEMENT: Probiotics|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: LASIK Using the Alcon Allegretto Wavefront-Guided Excimer Laser vs AMO Visx Wavefront-Guided Excimer Laser
Status: COMPLETED
Conditions: Myopia|Astigmatism
Interventions: PROCEDURE: Wavefront-guided LASIK - Allegretto|PROCEDURE: Wavefront-guided LASIK - AMO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Aggressive Versus Conservative Phototherapy in Infants <1,000 Grams Birth Weight
Status: COMPLETED
Conditions: Hyperbilirubinemia, Neonatal|Jaundice, Neonatal|Infant, Newborn|Infant, Low Birth Weight|Infant, Small for Gestational Age|Infant, Premature
Interventions: PROCEDURE: Aggressive Phototherapy 501-750g|PROCEDURE: Aggressive Phototherapy 751-1000g|PROCEDURE: Conservative Phototherapy 501-750g|PROCEDURE: Conservative Phototherapy 751-1000g
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Varenicline Effects on Cue Reactivity and Smoking Reward/Reinforcement
Status: COMPLETED
Conditions: Tobacco Dependence
Interventions: DRUG: varenicline|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose:
Clinical trial: Promoting Safety Plan and Coping Strategy Use Among Adults With Suicidal Thoughts
Status: RECRUITING
Conditions: Suicide
Interventions: BEHAVIORAL: Personalized internal and external coping strategies|BEHAVIORAL: Personalized internal coping strategies|BEHAVIORAL: Personalized external coping strategies|BEHAVIORAL: General internal and external coping strategies|BEHAVIORAL: General internal coping strategies|BEHAVIORAL: General external coping strategies|BEHAVIORAL: General internal coping strategies, relaxation|BEHAVIORAL: General internal coping strategies, distraction|BEHAVIORAL: General internal coping strategies, physical activity
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Creating Opportunities Through Mentoring, Parental Involvement and Safe Spaces - Ethiopia
Status: COMPLETED
Conditions: Sexual Assault|Interpersonal Relations|Marital Status|Domestic Violence
Interventions: BEHAVIORAL: COMPASS|BEHAVIORAL: No intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Zileuton CR vs Placebo in Poorly Controlled Asthma Patients on Moderate Dose ICS
Status: TERMINATED
Conditions: Asthma
Interventions: DRUG: Zileuton CR|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Zolpidem on Outcomes Following Lumbar Spine Fusion
Status: RECRUITING
Conditions: Spine Fusion|Lumbar Spine Degeneration|Pain, Postoperative|Lumbar Spine Spondylosis
Interventions: DRUG: Zolpidem Tartrate 10 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pyridoxine, P2 Receptor Antagonism, and ATP-mediated Vasodilation in Young Adults
Status: COMPLETED
Conditions: Receptor Blockade
Interventions: DRUG: Adenosine Triphosphate|DRUG: Acetylcholine|DRUG: Sodium Nitroprusside|DRUG: Adenosine Diphosphate|DRUG: Adenosine Monophosphate|DRUG: Uridine Triphosphate|DRUG: Adenosine|DRUG: Vitamin B 6|DRUG: Pyridoxal 5'-Phosphate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety and Efficacy of Zevalin in the Treatment of Non-Hodgkin's Lymphoma
Status: TERMINATED
Conditions: Non-Hodgkin's Lymphoma
Interventions: DRUG: Zevalin (ibritumomab tiuxetan)|DRUG: Rituxan (rituximab)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Characterization of the Cardiac Reinnervation of Patients With Transposition of the Great Arteries Long After Repair With the Arterial Switch Operation. Correlation With Electrocardiographic and Exercise Test Parameters
Status: COMPLETED
Conditions: Congenital Heart Disease|Congenital Heart Defect|Transposition of the Great Arteries
Interventions: OTHER: Non intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Trial to Evaluate the Safety and Activity of Fruquintinib in Minority Populations With Advanced, Previously Treated Colorectal Cancer
Status: NOT_YET_RECRUITING
Conditions: Colorectal Cancer
Interventions: DRUG: Fruquintinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Safety and Effectiveness of The SherpaPak in Donation After Circulatory Death Heart Transplantation
Status: COMPLETED
Conditions: Heart Transplant Failure|Determination of Death|Outcomes Research|Extracorporeal Membrane Oxygenation
Interventions: DEVICE: Paragonix SherpaPak Cardiac Transport System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: The Effect of the Nurses Support Program on Fatigue in MS Patient
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Sclerosis|Fatigue|Sleep Hygiene|Quality of Life
Interventions: BEHAVIORAL: NURSE FOLLOW-UP PROGRAM SUPPORTED WITH WEB-BASED EDUCATION
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Trial of Neoadjuvant Ipilimumab Followed by Melphalan Via Isolated Limb Infusion for Patients With Unresectable In-transit Extremity Melanoma
Status: COMPLETED
Conditions: Unresectable Melanoma
Interventions: DRUG: Ipilimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Effectiveness of a New Non-Nucleoside Reverse Transcriptase Inhibitor (NNRTI), (+)-Calanolide A, in HIV-Positive Patients Who Have Never Received Anti-HIV Treatment
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Calanolide A
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Calcium Phosphate Cement With Patient-specific Implants for Cranial Reconstruction
Status: COMPLETED
Conditions: Cranial Defect
Interventions: DEVICE: patient-specific implant|DEVICE: cement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Neurophysiological Assessment in Patients With Multiple Sclerosis
Status: UNKNOWN
Conditions: Multiple Sclerosis|Demyelinating Disease|Inflammatory Disease
Interventions: OTHER: Neurophysiological assessment|OTHER: clinical assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Phase I Study of AZD1480 in Patients With Advanced Solid Malignancies and Advanced Hepatocellular Carcinoma in the Escalation Phase,Non-Small Cell Lung Cancer(NSCLC) and Non-smokers With Lung Metastasis and Gastric Cancer and Solid Tumour in the Expansion Phase.
Status: TERMINATED
Conditions: Solid Tumour|Advanced Solid Malignancies|Child-Pugh A to B7 Advanced Hepatocellular Carcinoma|EGFR and/or ROS Mutant NSCLC|Lung Metastasis Carcinoma|Gastric Cancer
Interventions: DRUG: AZD1480 Daily|DRUG: AZD1480 BID
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics and Pharmacodynamics of the Gametocytocidal and Post-treatment Chemoprotective Effects of Antimalarials
Status: ACTIVE_NOT_RECRUITING
Conditions: Uncomplicated Falciparum Malaria
Interventions: DRUG: Artemether-lumefantrine|DRUG: Dihydroartemisinin-piperaquine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Secondary Prevention of Osteoporotic Fractures in Residents of Long-Term Care Facilities
Status: COMPLETED
Conditions: Hip Fractures|Osteoporosis
Interventions: BEHAVIORAL: Long-term care facilities in the intervention arm will receive education and feedback audit on performance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE|Primary Purpose: PREVENTION
Clinical trial: Conventional vs Bipolar SIJ RFA for Treatment of Sacroiliac Joint Pain
Status: RECRUITING
Conditions: Sacroiliac Joint Complex|Low Back Pain
Interventions: PROCEDURE: Nimbus Sacroiliac Joint Radiofrequency Ablation (N-SIJRFA)|PROCEDURE: Conventional Sacroiliac Joint Radiofrequency Ablation (C-SIJRFA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ponatinib for FLT3-ITD Acute Myelogenous Leukemia
Status: UNKNOWN
Conditions: Acute Myeloid Lukemia
Interventions: DRUG: Ponatinib and Cytarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Impact of Sugammadex on Ileus After Abdominal Wall Reconstruction
Status: RECRUITING
Conditions: Hernia, Ventral|Ileus
Interventions: DRUG: Neostigmine / Glycopyrrolate|DRUG: Sugammadex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: ACP-196 (Acalabrutinib), a Novel Bruton Tyrosine Kinase (BTK) Inhibitor, for Treatment of Chronic Lymphocytic Leukemia, Richter's Syndrome or Prolymphocytic Leukemia
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Lymphocytic Leukemia|Small Lymphocytic Lymphoma|Richter's Syndrome|Prolymphocytic Leukemia
Interventions: DRUG: Acalabrutinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MS-553 in Diabetic Retinopathy Patients With Central Involved Macular Edema
Status: SUSPENDED
Conditions: Diabetic Macular Edema|Macular Edema|Type 2 Diabetes With Diabetic Macular Edema|Type 1 Diabetes With Diabetic Macular Edema|Diabetic Retinopathy
Interventions: DRUG: MS-553
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Nanoparticle Paclitaxel (ABI-007) for the Prevention of In-Stent Restenosis
Status: COMPLETED
Conditions: Coronary Restenosis
Interventions: DRUG: Nanoparticle Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Polyglycolic Acid Mesh (Neoveil) in Thyroid Cancer Surgery
Status: UNKNOWN
Conditions: Thyroid Gland Carcinoma|Thyroid Cancer|Thoracic Duct Leak
Interventions: DEVICE: Neoveil (Polyglycolic Acid Mesh)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: CH1701 for Prevention and Treatment of Radiation Burns
Status: UNKNOWN
Conditions: Cancer
Interventions: DRUG: CH1701 for prevention and treatment of radiation burns.|DRUG: Safety assessment of CH1701|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Efficacy of Nasal High Flow Oxygen Therapy With Rehabilitation in the Patients With Chronic Respiratory Failure
Status: COMPLETED
Conditions: Chronic Respiratory Failure|Nasal High Flow Therapy|Rehabilitation|Exercise Endurance
Interventions: DEVICE: nasal high flow therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Active Video Game on Metabolic, Cardiovascular, and Psychological Metrics in Older Adults
Status: COMPLETED
Conditions: Aging
Interventions: BEHAVIORAL: Active Video Game Exercise|BEHAVIORAL: Treadmill walking exercise|BEHAVIORAL: Sedentary Behavior
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assisted Animal Therapy: ReAnimal
Status: TERMINATED
Conditions: Anxiety|Mood Disorders|Post Traumatic Stress Disorder
Interventions: OTHER: Animal assisted therapy|BIOLOGICAL: Nasal swab sampling|BEHAVIORAL: STAI-Y and POMS Questionnaires|PROCEDURE: physiological parameters measure|OTHER: Visual Analog Scale (VAS)|BEHAVIORAL: Impact of Event Scale - Revised (IES-R)|BEHAVIORAL: satisfaction questionnaire|BIOLOGICAL: Rectal swab sampling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Efficacy and Safety of 1565-nm Non-ablative Fractional Laser Versus Long-pulsed 1064-nm Nd:YAG Laser in the Treatment of Enlarged Facial Pores
Status: UNKNOWN
Conditions: Enlarged Facial Pores
Interventions: DEVICE: laser treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT