pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Galactagogue Use in Lactating Women With Low Milk Supply
Status: RECRUITING
Conditions: Breast Milk Expression
Interventions: DIETARY_SUPPLEMENT: Galactagogue Supplement for Treatment of Low Milk Supply
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of a Restorative Glass Ionomer and a Bulk-fill Composite Resin
Status: ACTIVE_NOT_RECRUITING
Conditions: Tooth Disease
Interventions: DEVICE: Glass ionomer|DEVICE: Bulk-fill composite
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Difference Between Non-invasive High-frequency Oscillatory Ventilation and Non-invasive Continuous Airway Pressure Ventilation in COVID-19 With Acute Hypoxemia
Status: NOT_YET_RECRUITING
Conditions: COVID-19 Pneumonia|Non-invasive Ventilation
Interventions: DEVICE: Non-invasive high-frequency oscillatory ventilation|DEVICE: Non-invasive continuous positive airway pressure ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Subcutaneous Mircera for the Maintenance Treatment of Anemia in Participants With Chronic Kidney Disease Not on Dialysis
Status: COMPLETED
Conditions: Anemia
Interventions: DRUG: Methoxy Polyethylene Glycol-epoetin Beta
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness and Safety of Topical Hyaluronic Acid of Different Molecular Weights in Xerotic Skin Treatment
Status: COMPLETED
Conditions: Xerosis Cutis
Interventions: DRUG: Low molecular weight hyaluronic acid|DRUG: High molecular weight hyaluronic acid|DRUG: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility Intervention Trial of Two Types of Improved Cookstoves in Three Developing Countries
Status: COMPLETED
Conditions: Poisoning by Carbon Monoxide From Domestic Fuels|Respiratory Conditions Due to Other External Agents
Interventions: DEVICE: Improved, ventilated cookstove
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Randomised Placebo Controlled Trial of ART Plus Dual Long-acting HIV-specific Broadly Neutralising Antibodies (bNAbs).
Status: RECRUITING
Conditions: HIV/AIDS and Infections
Interventions: DRUG: Investigational Medicinal Product
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Placebo-Controlled Trial of CLBS16 in Subjects With Coronary Microvascular Dysfunction
Status: TERMINATED
Conditions: Coronary Microvascular Dysfunction|Coronary Microvascular Disease|Microvascular Coronary Artery Disease
Interventions: BIOLOGICAL: CLBS16|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Test if a Fixed-Dose Combination of Fluticasone Propionate/Albuterol Sulfate is Effective in Preventing Asthma Exacerbations
Status: RECRUITING
Conditions: Asthma
Interventions: DRUG: TEV-56248|DRUG: Albuterol sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, and Efficacy Study in Subjects With Advanced or Metastatic Breast Cancer
Status: TERMINATED
Conditions: Breast Cancer
Interventions: DRUG: KW-2450 in combination with lapatinib and letrozole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Novel Person-Centered Treatment Component for Substance Use Treatment
Status: COMPLETED
Conditions: Substance Use Disorders|Depression|Bipolar Disorder|Psychosis|Personality Disorders
Interventions: BEHAVIORAL: Natural Recovery-Horticulture|BEHAVIORAL: Natural Recovery-Art/Music
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intra-arterial Versus Systemic Thrombolysis for Acute Ischemic Stroke
Status: COMPLETED
Conditions: Stroke|Cerebrovascular Accident
Interventions: OTHER: Alteplase IA and/or mechanical thrombolysis|DRUG: Alteplase IV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral Bioavailability of Two Solid Formulations of GLPG0634
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: 200 mg GLPG0634 as capsules, fasted|DRUG: 200 mg GLPG0634 as tablets, fasted|DRUG: 200 mg GLPG0634 as tablets, fed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Symptom-inhibited Fentanyl Induction
Status: RECRUITING
Conditions: Opioid Use Disorder
Interventions: DRUG: Fentanyl|DRUG: Methadone|DRUG: Slow-release oral morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Maekmoondong-tang on Post-operative Cough in Patients With Lung Cancer
Status: UNKNOWN
Conditions: Postoperative Cough|Lung Cancer
Interventions: DRUG: Maekmoondong-tang|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Health Coaching: A Pilot Trial Among Reintegrating Veterans
Status: ACTIVE_NOT_RECRUITING
Conditions: Veteran Reintegration
Interventions: BEHAVIORAL: Health Coaching|BEHAVIORAL: VA Benefits Information
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Community RCT of the Effectiveness of Two Compression Bandaging Technologies
Status: COMPLETED
Conditions: Venous Ulcer
Interventions: DEVICE: Four-layer Bandage (Elastomeric)|DEVICE: Short-stretch Bandage (Non-elastomeric)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: In-person vs. Remote Wellness Support
Status: COMPLETED
Conditions: Depressive Disorder, Major|Bipolar Disorder|Schizo Affective Disorder|Schizophrenia
Interventions: BEHAVIORAL: CAT|BEHAVIORAL: R-CAT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of APG-2575 in Patients With Relapsed/Refractory CLL/SLL
Status: RECRUITING
Conditions: Chronic Lymphocytic Leukemia|Small Lymphocytic Lymphoma
Interventions: DRUG: APG2575
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability of Sacubitril/Valsartan in Heart Failure Patient With Reduced Ejection Fraction
Status: COMPLETED
Conditions: Heart Failure, Systolic
Interventions: DRUG: Sacubitril/valsartan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Glaucoma Treatment by Circular Cyclocoagulation Using High Intensity Focused Ultrasound With the EYEOP Medical Device
Status: COMPLETED
Conditions: Glaucoma
Interventions: DEVICE: EYEOP device
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Enhancing Brain Health by tDCS in Persons With Overweight and Obesity
Status: ACTIVE_NOT_RECRUITING
Conditions: Insulin Resistance|Obesity|Diabetes Type 2
Interventions: DEVICE: anodal transcranial direct current stimulation|DEVICE: cathodal transcranial direct current stimulation|DEVICE: sham transcranial direct current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Feasibility and Therapeutic Potential of Free Fat Grafts in the Treatment of Esophageal Strictures (ESOGRAFT)
Status: UNKNOWN
Conditions: Esophageal Stricture|Fat Graft
Interventions: PROCEDURE: Stricture dilation with CRE balloon|PROCEDURE: Autologous fat grafting
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of ARRY-371797 in Subjects Undergoing Third Molar Extraction
Status: COMPLETED
Conditions: Dental Pain
Interventions: DRUG: Placebo; oral|DRUG: Placebo; oral|DRUG: ARRY-371797, p38 inhibitor; oral|DRUG: ARRY-371797, p38 inhibitor; oral|DRUG: Celecoxib, COX-2 inhibitor; oral|DRUG: Placebo; oral|DRUG: ARRY-371797, p38 inhibitor; oral
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Preliminary Administration of EPO and Markers of Cardiac Ischemia Induced by CPB
Status: COMPLETED
Conditions: Myocardial Ischemia
Interventions: DRUG: epoetin beta|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparative Effects of ACBT and Slow Expiration in Patients With Chronic Obstructive Pulmonary Disease
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: OTHER: ACTIVE CYCLE OF BREATHING TECHNIQUES|OTHER: SLOW EXPIRATION WITH OPEN GLOTTIS IN LATERAL POSITION
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Feasibility Study to Evaluate the Safety of the TheraSphere Glioblastoma (GBM) Device in Patients With Recurrent GBM
Status: RECRUITING
Conditions: Glioblastoma Multiforme|Recurrent Glioblastoma
Interventions: DEVICE: TheraSphere GBM
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Subcuticular Suture Versus Staples for Closure of the Skin After Caesarean Section.
Status: COMPLETED
Conditions: Cesarean Section|Cicatrix
Interventions: PROCEDURE: Staples left, subcuticular suture right|PROCEDURE: Subcuticular suture left side and staples right
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: UCN-01 and Topotecan in Treating Patients With Recurrent, Persistent, or Progressive Advanced Ovarian Epithelial, Primary Peritoneal, or Fallopian Tube Cancer
Status: COMPLETED
Conditions: Fallopian Tube Cancer|Ovarian Cancer|Primary Peritoneal Cavity Cancer
Interventions: DRUG: 7-hydroxystaurosporine|DRUG: topotecan hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cisplatinum/Pemetrexed Versus Split-dose Cisplatinum/Pemetrexed In NSCLC
Status: UNKNOWN
Conditions: NSCLC
Interventions: DRUG: Cisplatinum|DRUG: Pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: Open Label Study to Evaluate the Effect of Kaempferia Parviflora in Support of Erectile Function and Male Sexual Health
Status: COMPLETED
Conditions: Erectile Function
Interventions: DIETARY_SUPPLEMENT: Kaempferia parviflora extract
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Safety and Efficacy of an Antibiotic Sponge in Diabetic Patients With a Mild Infection of a Foot Ulcer
Status: COMPLETED
Conditions: Diabetic Foot Ulcer
Interventions: DRUG: gentamicin-collagen sponge|DRUG: Levofloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of Chocolate With Plant Additives on Episodic Memory in Healthy Subjects Experiencing Test Anxiety
Status: COMPLETED
Conditions: Test Anxiety
Interventions: DIETARY_SUPPLEMENT: High Epicatechin/ Melissa|OTHER: Low Epicatechin/ Oat bran
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety and Efficacy of Long-term Treatment With SCT800 in Previously Treated Hemophilia A Patients.
Status: RECRUITING
Conditions: Hemophilia A
Interventions: DRUG: Recombinant Human Coagulation FVIII
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: FP-101 Versus Placebo in the Treatment of Menopausal Vasomotor Symptoms
Status: COMPLETED
Conditions: Vasomotor Symptoms|Menopause
Interventions: DRUG: FP-101
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Improvement of Fertilization Rate and Embryo Quality by Treating Calcium Ionophore in IVF Patients: a Sibling Oocyte Control Study
Status: RECRUITING
Conditions: IVF|Infertility|Artificial Oocyte Activation
Interventions: OTHER: calcium ionophore
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Utilizing A Genomic Sig for "BRCAness" to Eval the Efficacy of Satraplatin in Men With Met. Castration Resistant Prostate Ca
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: Satraplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rate Control Versus Rhythm Control For Postoperative Atrial Fibrillation
Status: COMPLETED
Conditions: Postoperative Atrial Fibrillation
Interventions: DRUG: Amiodarone|PROCEDURE: DC-cardioversion|DRUG: Rate Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Performance of the Indirect Resin Composite Restorations in Endodontically Treated Teeth
Status: COMPLETED
Conditions: Endodontically Treated Teeth
Interventions: OTHER: Cuspal reduction in MOD cavity in endodontically treated teeth|OTHER: No cuspal reduction in MOD cavity in endodontically treated teeth
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Internal Radiation Therapy With Y-90 Microspheres, External Radiation Therapy With Tomotherapy, and Fluorouracil in Treating Patients With Newly Diagnosed or Recurrent Pancreatic Cancer and Liver Metastases That Cannot Be Removed By Surgery
Status: UNKNOWN
Conditions: Metastatic Cancer|Pancreatic Cancer
Interventions: DRUG: fluorouracil|RADIATION: selective external radiation therapy|RADIATION: tomotherapy|RADIATION: yttrium Y 90 glass microspheres|RADIATION: yttrium Y 90 resin microspheres
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Over-the-Counter Antihistamines & Heat Stress
Status: RECRUITING
Conditions: Heat Illness|Allergic Rhinitis|Heat Injury|Sudomotor Sympathetic Dysfunction
Interventions: DRUG: 50 mg Diphenhydramine|DRUG: 10 mg Loratadine|DRUG: 5 mg Desloratadine|OTHER: Placebo (Sugar Pill)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Comparison of Remimazolam and Propofol Combination vs. Propofol in IOM
Status: NOT_YET_RECRUITING
Conditions: Neurologic Disorder
Interventions: DRUG: Remimazolam besylate + propofol MCT|DRUG: Propofol MCT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: EUS-Gallbladder vs CDS as First Line in MBDO- Palliative (CARPEGIEM Trial)
Status: NOT_YET_RECRUITING
Conditions: Malignant Biliary Obstruction|Biliary Tract Neoplasms|Pancreatic Cancer Non-resectable
Interventions: PROCEDURE: Endoscopic biliary drainage|DEVICE: Lumen-apposing metal stent (LAMS) and double-pigtail plastic stent (DPPS)|DEVICE: Lumen-apposing metal stent (LAMS) and double-pigtail plastic stent (DPPS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testing the Addition of MEDI4736 (Durvalumab) to Chemotherapy Before Surgery for Patients With High-Grade Upper Urinary Tract Cancer
Status: RECRUITING
Conditions: Renal Pelvis and Ureter Urothelial Carcinoma
Interventions: PROCEDURE: Biopsy|PROCEDURE: Biospecimen Collection|DRUG: Cisplatin|PROCEDURE: Computed Tomography|DRUG: Doxorubicin Hydrochloride|BIOLOGICAL: Durvalumab|DRUG: Gemcitabine Hydrochloride|PROCEDURE: Magnetic Resonance Imaging|DRUG: Methotrexate|BIOLOGICAL: Pegfilgrastim|PROCEDURE: Therapeutic Conventional Surgery|DRUG: Vinblastine Sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized Trial of Rosuvastatin Loading Combined With Early hydrAtion Versus Standard-of-care Medications for the Prevention of CIAKI in Patient With AMI Undergoing Emergency PCI
Status: WITHDRAWN
Conditions: Contrast-induced Acute Kidney Injury|ST Elevation Myocardial Infarction|Primary PCI|Rosuvastatin|Hydration
Interventions: DRUG: hydration plus rosuvastatin therapy|DRUG: Standard therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Palm Tocotrienols in Chronic Hemodialysis (USA)
Status: COMPLETED
Conditions: End Stage Renal Disease|Chronic Kidney Disease
Interventions: DIETARY_SUPPLEMENT: TRF (Tocotrienol-rich-fraction)|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Comparing OHRQoL: One or Two Sessions for Wisdom Teeth Removal
Status: COMPLETED
Conditions: Impacted Third Molar Tooth|Impacted Tooth
Interventions: PROCEDURE: Single-Session Bilateral Mandibular Third Molar Extraction|PROCEDURE: Two-Session Bilateral Mandibular Third Molar Extraction
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rituximab Vasculitis Maintenance Study
Status: COMPLETED
Conditions: Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis|Microscopic Polyangiitis|Wegener Granulomatosis
Interventions: BIOLOGICAL: Rituximab|DRUG: Azathioprine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate Ompenaclid Combined With FOLFIRI Plus Bevacizumab in Advanced/Metastatic Colorectal Cancer
Status: RECRUITING
Conditions: Colorectal Cancer|Metastatic Colon Cancer
Interventions: DRUG: Ompenaclid (RGX-202)|DRUG: Placebo|DRUG: Bevacizumab|DRUG: FOLFIRI regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 1, Randomised Double Blinded Placebo Controlled Study of ASLAN003
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: ASLAN003 ACTIVE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Fine and Gross Motor Function and Relationship With Muscle Tone in Older Adults With and Without Dementia
Status: COMPLETED
Conditions: Dementia|Gait|Balance|Muscle Tone|Fine Motor Function|Paratonia
Interventions: OTHER: Gait accelerometry|OTHER: balance accelerometry|OTHER: Fine motor skill test|DIAGNOSTIC_TEST: Paratonia Assessment Instrument (PAI)|OTHER: myotonometric measurement of muscle tone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study of Brentuximab Vedotin Combined With Nivolumab for Relapsed or Refractory Hodgkin Lymphoma
Status: COMPLETED
Conditions: Hodgkin Lymphoma
Interventions: DRUG: brentuximab vedotin|DRUG: nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Psychosocial Tele-health Stigma Intervention for Youth Living With HIV in Vietnam
Status: COMPLETED
Conditions: Hiv|Stigma, Social
Interventions: BEHAVIORAL: CBT-based supportive skills delivered by phone by lay coaches
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Abemaciclib (LY2835219) Plus Fulvestrant Compared to Placebo Plus Fulvestrant in Previously Treated Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Neoplasm|Neoplasm Metastasis
Interventions: DRUG: Abemaciclib|DRUG: Fulvestrant|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Two Strategies for Methicillin-resistant Staphylococcus Aureus (MRSA) Infection Prevention in Surgical Patients
Status: COMPLETED
Conditions: MRSA Infection
Interventions: OTHER: Rapid molecular MRSA test|BEHAVIORAL: Hand hygiene promotion
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Infracyanine Green vs Brilliant Blue G in Macular Hole Inverted Flap Surgery: A Swept Source OCT Analysis.
Status: COMPLETED
Conditions: Macular Holes
Interventions: DEVICE: Inverted inner limiting membrane flap technique for large full thickness macular holes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Exploration of Arrhythmia Burden in Cardiac Amyloidosis Using Implantable Loop Recorders
Status: UNKNOWN
Conditions: Arrythmia|Cardiac Amyloidosis|Systemic AL Amyloidosis|Sudden Cardiac Death
Interventions: DEVICE: LINQ device - implantable cardiac monitor - referred to in the application as "implantable loop recorder" or "ILR")
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Guided Bone Regeneration Around Immediate Implants
Status: COMPLETED
Conditions: Missing Tooth
Interventions: PROCEDURE: Minimally Traumatic Tooth Extraction|DEVICE: Immediate Implant Placement|BIOLOGICAL: Bone Graft Placement|BIOLOGICAL: Membrane placement|BIOLOGICAL: Collagen plug placement|DRUG: Medications
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Phase 2, Double-blind, Placebo-controlled Study of the Efficacy and Safety of Belumosudil in Subjects With Moderate/Severe Chronic Plaque Psoriasis
Status: COMPLETED
Conditions: Chronic Plaque Psoriasis
Interventions: DRUG: Belumosudil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Glucose Variability in Type 1 Diabetes and Its Effect on Factors That Influence New Vessel Formation
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: DEVICE: Continuous Glucose Monitor (CGM) and Telemedicine (Enlite Guardian real-time system Medtronic®)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Ambispective Study to Assess the Effect of Pretreatment With a Levonorgestrel-Releasing Intrauterine System Versus Oral Progestin
Status: UNKNOWN
Conditions: Adenomyosis|IVF
Interventions: DEVICE: levonorgestrel-releasing intrauterine device (LNG-IUS)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Intratumoral Poly-ICLC Plus Low Dose Local Radiation in Low Grade Recurrent B and T Cell Lymphoma
Status: TERMINATED
Conditions: B Cell Lymphoma|T Cell Lymphoma
Interventions: DRUG: Poly-ICLC
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Perianal Abscess Packing Randomized ControlledTrial Pilot Study
Status: COMPLETED
Conditions: Perianal Abscess
Interventions: PROCEDURE: Intervention Group (Non-Packing)|PROCEDURE: Control group (Packing)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Investigation of the Safety, Dosing Frequency and Anti-Scarring Potential of Two Concentrations of Intradermal Avotermin (Juvista)
Status: COMPLETED
Conditions: Cicatrix|Wound Healing|Re-epithelialization
Interventions: DRUG: Avotermin|DRUG: Avotermin|DRUG: Avotermin|DRUG: Placebo|DRUG: Placebo|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of US-guided TAP Block in Breast Reconstruction Surgery With Abdominal Myocutaneous Flap
Status: COMPLETED
Conditions: Breast Reconstruction Surgery|TAP Block|Ultrasound|Analgesia|Efficacy
Interventions: OTHER: US-guided Bilateral TAP block
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Videolaryngoscopes for Double Lumen Tube Intubations
Status: COMPLETED
Conditions: Thoracic Surgery|Need for Double Lumen Tubes
Interventions: DEVICE: Macintosh|DEVICE: Glidescope®|DEVICE: Airtraq®|DEVICE: King Vision™
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Immunotherapy as Second-line in Patient With Small Cell Lung Cancer
Status: COMPLETED
Conditions: Small Cell Lung Cancer|Small Cell Lung Cancer Limited Stage|Small Cell Lung Cancer Extensive Stage
Interventions: DRUG: Atezolizumab|DRUG: Topotecan|DRUG: Carboplatin|DRUG: Etoposide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intermittent Theta Burst Stimulation (iTBS) for Emotion Regulation in Bipolar Disorder
Status: NOT_YET_RECRUITING
Conditions: Bipolar Disorder
Interventions: DEVICE: Transcranial Magnetic Stimulation (TMS)|DEVICE: Sham (placebo) TMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: CombinADO: Evaluation of an Intervention Aimed at Improving HIV Outcomes Among Adolescents and Young Adults Living With HIV in Mozambique
Status: RECRUITING
Conditions: HIV
Interventions: BEHAVIORAL: Radio Ads|BEHAVIORAL: Community Sensitization Campaign|BEHAVIORAL: Informational Posters|BEHAVIORAL: Motivation Walls|OTHER: Pill Container|OTHER: CombinADO-specific training for healthcare workers|OTHER: One Stop Shop Model of Care|OTHER: Treatment Toolkit|OTHER: Self-reflection Kit|BEHAVIORAL: Peer Support|BEHAVIORAL: Informational and motivational Video|BEHAVIORAL: Support groups- caregivers of adolescents and young adults living with HIV|BEHAVIORAL: Support groups- adolescents and young adults living with HIV|BEHAVIORAL: Mental health screening and linkage to adolescent-focused mental health support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study of Cetuximab Combined With Cisplatin or Carboplatin/Pemetrexed as First Line Treatment in Patients With Malignant Pleural Mesothelioma.
Status: COMPLETED
Conditions: Cancer
Interventions: DRUG: Cetuximab (Erbitux)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fed Bioavailability Study of Zonisamide Capsules
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Zonisamide 100 mg Capsule|DRUG: Zonisamide (Zonegran®) 100 mg Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Oral Versus Intravenous Acetaminophen for Postoperative Pain Control
Status: TERMINATED
Conditions: Postoperative Pain|IVF
Interventions: DRUG: acetaminophen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Investigation of Lipedema, Lymphedema and Vascular Malformations by Multispectral Optoacoustic Tomography (MSOT)
Status: ENROLLING_BY_INVITATION
Conditions: Lipedema|Lymphedema|Vascular Malformations
Interventions: DIAGNOSTIC_TEST: MSOT
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy of Acute Lymphoblastic Leukemia-Based Therapy in Treating Patients With Acute Leukemia of Ambiguous Lineage
Status: NOT_YET_RECRUITING
Conditions: Acute Leukemia of Ambiguous Lineage
Interventions: DRUG: vincristine|DRUG: daunorubicin|DRUG: cyclophosphamide|DRUG: L-Asparaginase|DRUG: prednisone|DRUG: mercaptopurine|DRUG: methotrexate|DRUG: dexamethasone|DRUG: Tyrosine kinase inhibitor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HFNO or Conventional Oxygen Therapy for Patients With Acute Hypoxemic Respiratory Distress
Status: RECRUITING
Conditions: Acute Hypoxemic Respiratory Distress
Interventions: DEVICE: High Flow Nasal Oxygen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Graft-Augmented Rectocele Repair-A Randomized Surgical Trial
Status: COMPLETED
Conditions: Rectocele
Interventions: PROCEDURE: Graft augmented posterior repair|PROCEDURE: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MT-8554 for Reduction of Vasomotor Symptoms in Postmenopausal Women
Status: COMPLETED
Conditions: Menopause Hot Flashes
Interventions: DRUG: MT-8554 1mg|DRUG: MT-8554 5mg|DRUG: MT-8554 10mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate CIN-107 for the Treatment of Patients With Uncontrolled Hypertension and Chronic Kidney Disease
Status: COMPLETED
Conditions: Uncontrolled Hypertension|Chronic Kidney Diseases
Interventions: DRUG: CIN-107|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Chronic Posterior Laryngitis With Suspected Laryngopharyngeal Reflux
Status: COMPLETED
Conditions: Chronic Posterior Laryngitis (CPL)
Interventions: DRUG: Esomeprazole|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Post Marketing Surveillance to Evaluate the Safety of Desidustat for the Treatment of Anemia in Subjects With Chronic Kidney Disease (CKD).(Real World Evidence Study)
Status: RECRUITING
Conditions: Chronic Kidney Diseases|Anemia of Chronic Kidney Disease
Interventions: DRUG: Desidustat
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Resin Salve and Octenidine in Patients With Neuropathic Diabetic Foot Ulcers
Status: COMPLETED
Conditions: Diabetes Mellitus|Diabetes Complications|Diabetic Neuropathies|Wound Infection
Interventions: DEVICE: Resin salve treatment|DEVICE: Octenidine treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dapagliflozin DPPIV Inhibitor add-on Study
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: Dapagliflozin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Short Term Effectiveness of EEA Versus PPH Stapler for III Degree Hemorrhoids
Status: COMPLETED
Conditions: III Degree Hemorrhoids
Interventions: PROCEDURE: stapled hemorrhoidopexy|PROCEDURE: stapled hemorrhoidopexy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose-finding, Safety Study of Plasmid DNA Therapeutic Vaccine to Treat Cervical Intraepithelial Neoplasia
Status: COMPLETED
Conditions: Cervical Intraepithelial Neoplasia
Interventions: BIOLOGICAL: GX-188E
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Sodium Heparin for Prophylaxis of Venous Thromboembolism in Surgical Patients
Status: UNKNOWN
Conditions: Venous Thromboembolism
Interventions: BIOLOGICAL: heparin sodium - Hipolabor|BIOLOGICAL: Heparin sodium - APP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of the Mammalian Target of Rapamycin (mTor Rapamycin) Inhibitor in Vascular Malformations
Status: COMPLETED
Conditions: Cardiovascular Abnormalities
Interventions: DRUG: Sirolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Evinacumab (REGN1500) in Participants With Persistent Hypercholesterolemia
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DRUG: Evinacumab|DRUG: Matching placebo|OTHER: Background Lipid Modifying Therapy (LMT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Therapy Using Lenalidomide (Revlimid)- Low Dose Dexamethasone and Rituximab for Treatment of Rituximab-Resistant, Non-Aggressive B-Cell Lymphomas
Status: COMPLETED
Conditions: Follicular Lymphoma|Marginal Zone B-Cell Lymphoma|MALT Lymphoma|Lymphoma of Mucosa-Associated Lymphoid Tissue|Lymphoma, Small Lymphocytic|Waldenstrom Macroglobulinemia|Mantle-Cell Lymphoma
Interventions: DRUG: Lenalidomide|DRUG: Dexamethasone|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Video Gaming for Home Rehabilitation for Children With Hemiplegic Cerebral Palsy in Costa Rica
Status: ACTIVE_NOT_RECRUITING
Conditions: Hemiplegic Cerebral Palsy
Interventions: OTHER: Bootle Blast Home Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tranexamic Acid in Off-pump Coronary Surgery
Status: COMPLETED
Conditions: Off Pump Coronary Artery Bypass Surgery
Interventions: DRUG: Tranexamic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fixed Versus Flexible Dosing of Pregabalin in Patients With Fibromyalgia
Status: COMPLETED
Conditions: Fibromyalgia
Interventions: DRUG: Pregabalin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: PNF and Frenkel's Exercises for Postmenopausal Women
Status: COMPLETED
Conditions: Postmenopausal Symptoms
Interventions: OTHER: PNF exercise|OTHER: Frenkel exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Perfusion Imaging With Myocardial Contrast Echocardiography in HCM
Status: UNKNOWN
Conditions: Hypertrophic Cardiomyopathy
Interventions: DRUG: Echo and myocardial contrast echocardiography perfusion imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Multimodal Analgesia Versus Traditional Opiate Based Analgesia
Status: UNKNOWN
Conditions: Cardiac Surgery
Interventions: DRUG: Ketamine|DRUG: Lidocaine|DRUG: Dexmedetomidine|DRUG: Gabapentin|DRUG: Tylenol|DRUG: Gabapentin Pill|DRUG: Tylenol Pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Investigation to Evaluate the Safety and Efficacy of Zirconia Ceramic Blocks for Use in Dental Prostheses.
Status: NOT_YET_RECRUITING
Conditions: Dental Prosthesis
Interventions: DEVICE: Zirconia Dental Ceramics
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevention and Early Detection and Intervention of Post-Coronary Artery Bypass Grafting Surgery (CABG) Acute Kidney Injury (AKI)
Status: COMPLETED
Conditions: Acute Renal Injury|Preventive Measures
Interventions: PROCEDURE: Standard of Care plus Nephrology Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Randomized Trial Comparing Partial Resection of Inferior Turbinate(PRIT) and Radiofrequency Ablation(RFA) for Inferior Turbinate Reduction
Status: WITHDRAWN
Conditions: Nasal Obstruction|Septal Deformity|Turbinate Hypertrophy
Interventions: PROCEDURE: Partial Resection of Inferior Turbinates (PRIT)|PROCEDURE: Radiofrequency Ablation (RFA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Modified Measles Virus (MV-NIS) for Children and Young Adults With Recurrent Medulloblastoma or Recurrent ATRT
Status: COMPLETED
Conditions: Medulloblastoma, Childhood, Recurrent|Atypical Teratoid/Rhabdoid Tumor|Medulloblastoma Recurrent
Interventions: BIOLOGICAL: Modified Measles Virus|BIOLOGICAL: Modified Measles Virus Lumbar Puncture
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Aerobic Exercises Versus Incentive Spirometer Device on Post-covid Pulmonary Fibrosis Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Lung Fibrosis Interstitial|Post-COVID-19 Syndrome
Interventions: OTHER: Aerobic Exercises|DEVICE: Incentive Spirometer Device|OTHER: Traditional Chest Physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pitolisant Effects on Alcohol Self-Administration in Heavy Drinkers
Status: TERMINATED
Conditions: Alcohol Use Disorder|Alcohol Drinking
Interventions: DRUG: Pitolisant|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Evaluation of Giomer Varnish vs Fluoride Varnish as Desensitizing Agents in Teeth With MIH
Status: NOT_YET_RECRUITING
Conditions: Molar Incisor Hypomineralization
Interventions: COMBINATION_PRODUCT: Giomer varnish|COMBINATION_PRODUCT: Fluoride varnish
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Effectiveness, Security And Radiological Changes In Epiduroscopy For Lumbar Stenosis
Status: COMPLETED
Conditions: Spinal Stenosis, Lumbar Region, With Neurogenic Claudication
Interventions: PROCEDURE: Epiduroscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Infant Pulmonary Mechanics: High Flow Nasal Cannula Versus Nasal CPAP
Status: WITHDRAWN
Conditions: Respiratory Distress|Lung Injury
Interventions: DEVICE: Heated Humidified High Flow Nasal Cannula|DEVICE: Nasal Continuous Positive Airway Pressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: CO as a Stimulant for Mitochondrial Biogenesis in Human Cardiac Muscle
Status: TERMINATED
Conditions: Cardiac Disease|Mitochondrial Biogenesis|Carbon Monoxide
Interventions: DRUG: 200ppm CO for one hour|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Resistance Exercise Training and Amino Acid Leucine Supplementation in Frail Elderly Women
Status: COMPLETED
Conditions: Frail Elderly
Interventions: DIETARY_SUPPLEMENT: Leucine|DIETARY_SUPPLEMENT: Alanine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Relative Bioavailability Study of Fluticasone Furoate and Levocabastine
Status: COMPLETED
Conditions: Rhinitis, Allergic, Perennial and Seasonal
Interventions: DRUG: FF/LEV FDC|DRUG: FF|DRUG: LEV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of BI 1356 as Single Dose on the QT Interval in Healthy Female and Male Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BI 1356, low dose|DRUG: BI 1356, high dose|DRUG: Placebo|DRUG: Moxifloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Dietary Incorporation of Lentils to Improve Metabolic Health
Status: COMPLETED
Conditions: Waist, Hypertriglyceridemic
Interventions: BEHAVIORAL: Dietary Lentil Intake|BEHAVIORAL: No Dietary Lentil CONTROL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Using MC1R Genotype to Impact Melanoma Risk Behavior
Status: COMPLETED
Conditions: Melanoma (Skin)|Squamous Cell Carcinoma|Squamous Cell Cancer|Skin Cancer|Basal Cell Carcinoma|Basal Cell Cancer
Interventions: BEHAVIORAL: Personalized Information|BEHAVIORAL: Standard Information|OTHER: DNA Extraction Determination of MC1R Genotypes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: MRI Study of Antidepressants in the Treatment of Refractory Functional Dyspepsia
Status: UNKNOWN
Conditions: Therapeutic Mechanism of Antidepressants for Refractory FD
Interventions: DRUG: selective serotonin reuptake inhibitor (SSRI) or serotonin noradrenaline reuptake inhibitor (SNRI) antidepressants|OTHER: conventional therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Persistence of Two GBS Antibodies in Women Previously Immunized With a GBS Vaccine
Status: COMPLETED
Conditions: Group B Streptococcus (GBS) Disease
Interventions: BIOLOGICAL: Group B streptococcus (GBS) vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of T3 on the Incidence of Atrial Fibrillation in Patients Undergoing Cardiac Surgery
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DRUG: Triiodothyronine|DRUG: triiodothyronine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Prenatal Tobacco Smoke Exposure on Lung Function and Respiratory Epithelium Functionality in Newborns
Status: COMPLETED
Conditions: Pregnancy Related|Tobacco Smoking|Lung Smokers|Newborn
Interventions: DIAGNOSTIC_TEST: lung function tests|DIAGNOSTIC_TEST: Nasal brushing
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Contribution of Parent-infant Interaction While Singing During Kangaroo Care, on Preterm-infants' Autonomic Stability and Parental Anxiety Reduction
Status: COMPLETED
Conditions: PreTerm Birth|Stress Reaction
Interventions: BEHAVIORAL: Music therapy and Kangaroo care|BEHAVIORAL: Kangaroo Care alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Co-administration Lidocaine and Dexmedetomidine on Quality of Recovery
Status: COMPLETED
Conditions: Lidocaine|Dexmedetomidine|Quality of Recovery(QoR-40), Preoperative and Postoperative
Interventions: DRUG: Co-administration Lidocaine and Dexmedetomidine|DRUG: Dexmedetomidine infusion|DRUG: Lidocaine infusion|DRUG: Saline infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT