pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Resiliency Programming for Caregivers of Children With Learning and Attentional Difficulties
Status: NOT_YET_RECRUITING
Conditions: Parenting|Stress|Learning Disabilities, Child|Attention Difficulties
Interventions: BEHAVIORAL: SMART-3RP|BEHAVIORAL: Health Education Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Pharmacokinetics of LY2624803 in Subjects With Hepatic Impairment
Status: TERMINATED
Conditions: Insomnia
Interventions: DRUG: LY2624803
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Computerized Intervention for Distress Intolerance
Status: COMPLETED
Conditions: Cannabis Use Disorder
Interventions: BEHAVIORAL: Computerized Distress Intolerance Intervention|BEHAVIORAL: Computerized Healthy Behaviors Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Sweet Orange and Pomegranate Extract Supplementation on Exercise Capacity in Middle-aged Adults
Status: UNKNOWN
Conditions: Exercise Capacity
Interventions: DIETARY_SUPPLEMENT: Sweet orange and pomegranate extract|OTHER: Maltodextrin control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Identifying Electrophysiological Targets for Transcranial Magnetic Stimulation in Cocaine Use Disorder
Status: NOT_YET_RECRUITING
Conditions: Cocaine Use Disorder
Interventions: DEVICE: TMS to dmPFC|DEVICE: TMS to dlPFC|DEVICE: Sham iTBS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effects of Strawberries on Blood Pressure in Postmenopausal Women
Status: COMPLETED
Conditions: Hypertension|Cardiovascular Diseases|Vascular Diseases
Interventions: DIETARY_SUPPLEMENT: 25 g of Freeze-dried Strawberry Powder|DIETARY_SUPPLEMENT: 50 g of Freeze-dried Strawberry Powder|DIETARY_SUPPLEMENT: Placebo Powder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of Skin Quality Improvement After Adipose-drived Stem Cell Transfer in Irradiated Breasts
Status: WITHDRAWN
Conditions: Breast Neoplasms|Skin Abnormalities
Interventions: BIOLOGICAL: Adipose SVF cell|BIOLOGICAL: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Foodprint 1.0: Physiological Acute Responses After Consumption of Confectionary Products
Status: COMPLETED
Conditions: Glucose, High Blood|Inflammatory Response|Oxidative Stress|Endotoxemia
Interventions: OTHER: control snack|OTHER: control cream|OTHER: cream version 1|OTHER: cream version 2|OTHER: cream version 3|OTHER: control chocolate bar|OTHER: chocolate bar version 1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Cetuximab Plus P-HDFL for the First-Line Treatment of Advanced Gastric Cancer
Status: UNKNOWN
Conditions: Stomach Neoplasms
Interventions: DRUG: Cetuximab, Cisplatin,5-Fluorouracil,Leucovorin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Epirubicin, Cyclophosphamide, and Paclitaxel With or Without Gemcitabine in Treating Women Who Are Undergoing Surgery for Early Breast Cancer
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: DRUG: cyclophosphamide|DRUG: epirubicin hydrochloride|DRUG: gemcitabine hydrochloride|DRUG: paclitaxel|GENETIC: comparative genomic hybridization|GENETIC: microarray analysis|GENETIC: mutation analysis|PROCEDURE: conventional surgery|PROCEDURE: neoadjuvant therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: MelPRO-0322 (CRISTINA Trial) [miCrobiome pRedIctS aPD1 effecTivnes In melaNoma pAtietns]
Status: RECRUITING
Conditions: Melanoma, Skin|Melanoma Stage Iii
Interventions: DIAGNOSTIC_TEST: Gut microbiota analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Improving Pain Management and Opioid Safety for Patients With Cirrhosis
Status: COMPLETED
Conditions: Cirrhosis, Liver
Interventions: BEHAVIORAL: Liver Education About Pain (LEAP)|BEHAVIORAL: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study to Evaluate the Effect of Single-Dose Intravenous Rifampin as a Prototypic Inhibitor of Organic Anion Transporting Polypeptide (OATP) 1B1 and OATP1B3 on the Single-Dose Pharmacokinetics (PK) of Oral TAK-906 in Healthy Adult Participants
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: TAK-906|DRUG: Rifampin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Association Between CBT-I Dose, Sleep Duration, and Fatigue in Breast Cancer Patients
Status: RECRUITING
Conditions: Chronic Insomnia|Cancer-related Problem/Condition|Cancer-Related Syndrome
Interventions: BEHAVIORAL: Cognitive Behavioral Therapy for Insomnia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ESP in Breast Surgery Due to Cancer
Status: COMPLETED
Conditions: Breast Cancer|Pain, Acute|Anesthesia, Local
Interventions: PROCEDURE: Erector spinae plane block|PROCEDURE: Sham block|PROCEDURE: General anesthesia|PROCEDURE: Patient-controlled analgesia|DRUG: Oxycodone|DRUG: paracetamol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Memantine Augmentation of Lamotrigine Incomplete-Response in Bipolar Depression
Status: COMPLETED
Conditions: Bipolar Depression
Interventions: DRUG: Memantine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized Clinical Trial Comparing Hall vs. Conventional Technique in Primary Molars.
Status: RECRUITING
Conditions: Dental Caries
Interventions: PROCEDURE: Hall Crown Technique|PROCEDURE: Conventional SSC Technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Intraperitoneal Oxaliplatin and Fluorouracil for the Treatment of Patients With Peritoneal Metastases From Colorectal Cancer
Status: RECRUITING
Conditions: Metastatic Colorectal Carcinoma|Metastatic Malignant Neoplasm in the Peritoneum|Stage IV Colorectal Cancer AJCC v8
Interventions: PROCEDURE: Biopsy|PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|PROCEDURE: Diagnostic Laparoscopy|DRUG: Fluorouracil|PROCEDURE: Magnetic Resonance Imaging|DRUG: Oxaliplatin|PROCEDURE: Surgical Procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Intermittent Oro-esophageal Tube Feeding on Severe Traumatic Brain Injury Patients With Tracheostomy
Status: TERMINATED
Conditions: Traumatic Brain Injury
Interventions: BEHAVIORAL: Rehabilitation therapy|DEVICE: Intermittent Oro-esophageal Tube Feeding|DEVICE: Nasogastric tube feeding|DRUG: Reserpine|DRUG: Levofloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Liprotamase Efficacy Trial in Patients With Cystic Fibrosis-Related Exocrine Pancreatic Insufficiency
Status: COMPLETED
Conditions: Cystic Fibrosis|Exocrine Pancreatic Insufficiency
Interventions: DRUG: Liprotamase|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Cohort Study for the Following up of Conization
Status: UNKNOWN
Conditions: Precancerous Lesions|Conization|High Grade Intraepithelial Neoplasia|Uterine Cervical Cancer|Fertility|Pregnancy|Human Papillomavirus Infection
Interventions: DIAGNOSTIC_TEST: High-risk HPV|DIAGNOSTIC_TEST: TCT
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Dexamethasone in Supraclavicular Brachial Plexus Block for Anesthesia After Pediatric Hand/Wrist Surgery
Status: RECRUITING
Conditions: Wrist Disease|Hand Injuries and Disorders
Interventions: DRUG: Sodium Chloride 0.9% Inj|DRUG: 0,1mg/kg Dexamethasone|DRUG: 0,2mg/kg Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Virtual Physical Rehabilitation for Patients Living With Long COVID
Status: ACTIVE_NOT_RECRUITING
Conditions: COVID-19|Post COVID-19|Long COVID
Interventions: OTHER: Intervention Group: Virtual home-based rehabilitation plus usual outpatient care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Calcium Silicate Based Root Canal Medicament on Inflammatory Mediators
Status: COMPLETED
Conditions: Periapical; Infection
Interventions: DRUG: Calcium Hydroxide|DRUG: Calcium Silicate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial for the Evaluation of the Efficacy and Safety of EDL on Dyspepsia
Status: RECRUITING
Conditions: Functional Dyspepsia
Interventions: DIETARY_SUPPLEMENT: Extract of Dolichos lablab Linne (EDL)|OTHER: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Second Line Therapy to Treat Age-related Macular Degeneration (AMD) for Patients Not Responding Well to Lucentis Therapy by Itself
Status: WITHDRAWN
Conditions: Age Related Macular Degeneration
Interventions: DRUG: Visudyne|DRUG: Lucentis|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Exercise Training to Atrial Fibrillation
Status: ENROLLING_BY_INVITATION
Conditions: Atrial Fibrillation
Interventions: BEHAVIORAL: Aerobic training|BEHAVIORAL: Resistance training|BEHAVIORAL: Control physical exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Stopping Hydroxychloroquine in Elderly Lupus Disease
Status: RECRUITING
Conditions: Systemic Lupus Erythematosus
Interventions: DRUG: Hydroxychloroquine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ibrutinib and Nivolumab in Treating Patients With Previously-Treated Metastatic Kidney Cancer
Status: COMPLETED
Conditions: Metastatic Renal Cell Cancer|Stage IV Renal Cell Cancer
Interventions: DRUG: Ibrutinib|DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of D-chiro-inositol Treatments
Status: COMPLETED
Conditions: Inositol|Testosterone|Insulin|Ovulation|Asprosin
Interventions: DIETARY_SUPPLEMENT: D-chiro-inositol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Adjunctive Use of Vitamin B3 and B9 on Myeloperoxidase Level in the GCF of Patients With Stage I and II Periodontitis
Status: UNKNOWN
Conditions: Periodontitis Stage I|Periodontal Diseases|Periodontal Inflammation|Periodontal Attachment Loss|Periodontitis|Periodontitis Stage II
Interventions: DRUG: Vitamin B3 100 MG Oral Tablet|DRUG: vitamin B9|DRUG: Placebo|PROCEDURE: full mouth non surgical periodontal treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: V501 Safety and Efficacy Study in Japanese Women Aged 16 to 26 Years (V501-110)
Status: COMPLETED
Conditions: Cervical Cancer|Cervical Intraepithelial Neoplasia|Adenocarcinoma in Situ
Interventions: BIOLOGICAL: V501
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Prevention of Dental Caries Lesions With Fluoride Varnish in Erupting First Permanent Molars
Status: COMPLETED
Conditions: Dental Caries
Interventions: DRUG: Fluoride Varnish|DRUG: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Oslo Footballplayers Iron Supplementation and Training (FIT) Study
Status: UNKNOWN
Conditions: Athletes|Iron|Endurance Performance|Hemoglobin|Intestinal Health|Microbiota
Interventions: DIETARY_SUPPLEMENT: Iron supplement (27mg)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Dapagliflozin at Discharge on Hospital Heart Failure Readmission
Status: COMPLETED
Conditions: Heart Failure|Diabetes
Interventions: DRUG: Dapagliflozin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: miRNAs in Periodontal Disease
Status: COMPLETED
Conditions: Periodontal Diseases|Periodontitis|Gingivitis
Interventions: DIAGNOSTIC_TEST: Control|DIAGNOSTIC_TEST: Smokers with periodontally healthy|DIAGNOSTIC_TEST: Non-smokers with gingivitis|DIAGNOSTIC_TEST: Smokers with gingivitis|DIAGNOSTIC_TEST: Non-smokers with periodontitis|DIAGNOSTIC_TEST: Smokers with periodontitis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Chemotherapy in Treating Children With Recurrent Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Leukemia
Interventions: BIOLOGICAL: filgrastim|DRUG: cladribine|DRUG: idarubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Relative Bioavailability and Effect of Food on the Coated Granule Formulation of Mitapivat in Healthy Participants
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Mitapivat tablets|DRUG: Mitapivat coated granules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Circulating Tumor DNA Methylation Guided Postoperative Adjuvant Chemotherapy for High-risk Stage II/III Colorectal Cancer
Status: RECRUITING
Conditions: High-risk Stage II Colorectal Cancer|Stage III Colorectal Cancer|Circulating Tumor DNA Methylation
Interventions: DRUG: mFOLFIRINOX adjuvant chemotherapy|DRUG: mFOLFOX6/XELOX adjuvant chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: UVA-1 for Treatment of Skin Tightening and Improvement of Hand Function in Scleroderma
Status: ENROLLING_BY_INVITATION
Conditions: Scleroderma
Interventions: DEVICE: UVA-1 Phototherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Single Dose Study of E6130 in Japanese Healthy Adult Male Subjects
Status: COMPLETED
Conditions: Japanese Healthy Adult Male Participants
Interventions: DRUG: E6130|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Phase I, 2-part (Part 1 Being a Single Dose Escalation and Part 2, a Parallel Group) Study of Toll-like Receptor (TLR4) Agonist (GSK1795091) in Healthy Subjects
Status: COMPLETED
Conditions: Cancer|Neoplasms
Interventions: DRUG: GSK1795091|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prevention of Acute Graft Versus Host Disease in Patients Undergoing Allogeneic ApoGraft Stem Cell Transplantation
Status: UNKNOWN
Conditions: Hematological Malignancies
Interventions: BIOLOGICAL: Allogeneic MPBC transplantation from matched related donor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalency Study of Losartan Potassium/Hydrochlorothiazide 100 mg/25 mg Tablet Under Fasted Conditions
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: losartan potassium / hydrochlorothiazide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Explore Papilocare Gel Efficacy to Repair of the Cervico-vaginal Mucosa With HPV High Risk Lesions.
Status: ACTIVE_NOT_RECRUITING
Conditions: Human Papilloma Virus|Human Papilloma Virus Infection|Cervix Lesion
Interventions: DEVICE: Papilocare vaginal gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sodium Bicarbonate and N-Acetylcysteine for Nephroprotection in Acute Myocardial Infarction
Status: COMPLETED
Conditions: Acute Myocardial Infarction|Acute Kidney Injury
Interventions: DRUG: Sodium bicarbonate plus NAC|DRUG: Saline hydration plus NAC
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Creation and Evaluation of a Mobile Intervention Team in Perinatal Psychiatry (0-3 Years) in Meurthe-et-Moselle Sud
Status: RECRUITING
Conditions: Abnormality
Interventions: OTHER: Mobile Intervention Team in Perinatal Psychiatry (EMPPer)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Passive Leg Raise During Cardiopulmonary Resuscitation
Status: UNKNOWN
Conditions: Leg Elevation|Hemodynamic Instability|Cardiopulmonary Resuscitation
Interventions: PROCEDURE: Hemodynamics parameters
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Vitamin D3 Supplementation in Critically Ill Patients Undergoing CRRT
Status: RECRUITING
Conditions: Vitamin D3 Deficiency
Interventions: DRUG: Vitamin D3 - 750 000 IU|DRUG: Vitamin D3 - 500 000 IU
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Benefit of Cone-beam CT and Robotic-Assisted Bronchoscopy During Bronchoscopy
Status: RECRUITING
Conditions: Lung Neoplasms|Diagnosis|Lung Cancer
Interventions: DIAGNOSTIC_TEST: Cone-Beam CT|DIAGNOSTIC_TEST: Robotic Assisted Bronchoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety and Efficacy of Triple and Quadruple Regimens as First Line Therapy for Management of Helicobacter Pylori Infection in Egyptians
Status: COMPLETED
Conditions: H.Pylori Infection
Interventions: DRUG: Omeprazole 20 MG Oral Tablet|DRUG: Amoxicillin 500Mg Tab|DRUG: Clarithromycin 500Mg Tab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Saxagliptin + Metformin Immediate Release (IR) Versus Metformin IR Alone in Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Saxagliptin plus metformin IR|DRUG: Placebo plus metformin IR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Value of Doppler Study of Central Retinal Artery in Diagnosis of Increased ICP
Status: ENROLLING_BY_INVITATION
Conditions: Increased Intracranial Pressure
Interventions: RADIATION: doppler study of central retinal artery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Personalized Attention-Deficit/Hyperactivity Disorder (ADHD) Medication Experiment Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: OTHER: Personalized ADHD Medication Experiment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Cardiac Rehabilitation: Optimisation of the Functional Capacity of Patients Hospitalized With Cardiac Disease
Status: COMPLETED
Conditions: Myocardial Ischemia|Heart Diseases
Interventions: PROCEDURE: Cardiac Rehabilitation (Phase I) - nurse intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Grape Seeds Versus Standard Measures for Prevention of Caries Incidence
Status: UNKNOWN
Conditions: Dental Caries
Interventions: DRUG: Grape Seed Extract mouth wash|DRUG: standard preventive measures|DRUG: antimicrobial and fluoride mouth wash
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: TRICIN: Prospective Study on the Efficacy of Single Topical Trichloroacetic Acid (TCA) 85% in the Treatment of Cervical Intraepithelial Neoplasia (CIN 1/2)
Status: COMPLETED
Conditions: Cervical Intraepithelial Neoplasia Grade 1|Cervical Intraepithelial Neoplasia Grade 2
Interventions: DEVICE: Trichloroacetic acid 85% (TCA)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Exenatide After Gastric Restriction
Status: UNKNOWN
Conditions: Morbid Obesity
Interventions: DRUG: Exenatide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A First-In-Human Study to Evaluate the Safety, Tolerability, and Efficacy of Si-544 in Adults With Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: si-544|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Ventavis in Patients With Pulmonary Hypertension (PH) Secondary to Chronic Obstructive Pulmonary Disease (COPD)
Status: TERMINATED
Conditions: Chronic Obstructive Pulmonary Disease|Pulmonary Hypertension
Interventions: DRUG: Iloprost|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Feasibility and Effect of Digital Cognitive Training in Mild Cognitive Impairment
Status: NOT_YET_RECRUITING
Conditions: Mild Cognitive Impairment
Interventions: BEHAVIORAL: Brain Blossom - Gamified Differential Outcome Training|BEHAVIORAL: Gamified Non-Differential Outcome Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Effects of VitamIN K2 and D3 supplementaTion on PET/MRI in Carotid Artery Disease
Status: NOT_YET_RECRUITING
Conditions: Coronary Artery Disease|Carotid Artery Disease
Interventions: DIETARY_SUPPLEMENT: MK-7 and vitamin D3|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Web-based Pain Coping Skills Training for Breast Cancer Survivors With AI-Associated Arthralgia
Status: RECRUITING
Conditions: Breast Cancer|Arthralgia|Pain, Chronic
Interventions: BEHAVIORAL: Online Pain Coping Skills Training|OTHER: Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: European Larynx Organ Preservation Study (ELOS) [MK-3475-C44]
Status: NOT_YET_RECRUITING
Conditions: Squamous Cell Carcinoma of Head and Neck|Hypopharyngeal Squamous Cell Carcinoma|Laryngeal Squamous Cell Carcinoma Stage III|Laryngeal Squamous Cell Carcinoma Stage IV|Squamous Cell Carcinoma of Larynx|Squamous Cell Carcinoma of the Larynx|Squamous Cell Carcinoma of the Larynx Stage III|Squamous Cell Carcinoma of the Larynx Stage IV|Laryngeal Squamous Cell Carcinoma|Laryngectomy; Status|Laryngeal Cancer|Laryngeal Neoplasms
Interventions: BIOLOGICAL: KEYTRUDA®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics of Metformin Intolerance
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Metformin Adverse Reaction
Interventions: DRUG: Metformin Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Placebo-Controlled Comparison of Two Different Brands of Modified-Release Oral Dosage Forms Regarding Safety and Efficacy in Children With Attention Deficit Hyperactivity Disorder (ADHD) Aged 6 - 14
Status: COMPLETED
Conditions: ADHD
Interventions: DRUG: Methylphenidate hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Metabolic Control Adolescents Type 1 Diabetes
Status: NOT_YET_RECRUITING
Conditions: 13-18 Year|Diagnosed at Least 6 Months Ago|HbA1C> 7.5|Being Able to Read and Write
Interventions: BEHAVIORAL: training sessions with peer interactive group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Exercise Therapy on Type II Diabetic Neuropathic Patients
Status: RECRUITING
Conditions: Diabetic Neuropathies
Interventions: OTHER: Experimental group 1 :Ball training|OTHER: Experimental group 2 :Frenkel Exercises|OTHER: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dutch EASYcare Study
Status: COMPLETED
Conditions: Cognition Disorders|Mood Disorder|Gait Disorder, Neurologic|Malnutrition
Interventions: BEHAVIORAL: Dutch EASYcare Study Geriatric Intermediate Care Programme
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Comparative Safety and Efficacy of Vaginal Dinoprostone Versus Lidocaine-prilocaine Cream in Copper IUD Insertion
Status: UNKNOWN
Conditions: Contraception
Interventions: DRUG: vaginal dinoprostone|DRUG: Lidocaine-prilocaine Cream|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transfemoral Implant of Inovare® Transcatheter Valve
Status: ACTIVE_NOT_RECRUITING
Conditions: Aortic Valve Stenosis
Interventions: DEVICE: INOVARE® Transcatheter Valve, NexusCath Delivery System, Aureus Expandable Introducer, Balloon Catheter for Pre-Dilation and Compression Device (Crimper)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Psycho-educational Training in Undergraduate Students at the University of Granada (Spain). Second Edition
Status: COMPLETED
Conditions: Empathy|Compassion|Attention|Psychological Distress|Life Stress|Anxiety|Creativity|Emotional Intelligence
Interventions: BEHAVIORAL: Más Presente, the UGRComp program|BEHAVIORAL: The MBSR program|BEHAVIORAL: Neuro-muscular stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Diabetes Technology Study of Real-Time Glucose Alerts in the Team Management of Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: BEHAVIORAL: Automated informatics driven education and social networking|BEHAVIORAL: Blood Glucose Notifications to Remote Caregivers|BEHAVIORAL: Frequency of Pattern Management
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Microbiota Transplant Therapy for Children With Both Autism Spectrum Disorder and Gastrointestinal Disorders
Status: NOT_YET_RECRUITING
Conditions: Autism Spectrum Disorder|Gastro-Intestinal Disorder|Constipation|Diarrhea
Interventions: COMBINATION_PRODUCT: MTP-101P|COMBINATION_PRODUCT: Vancomycin|COMBINATION_PRODUCT: Miralax|COMBINATION_PRODUCT: Antacid|COMBINATION_PRODUCT: Placebo MTP-101P|COMBINATION_PRODUCT: Placebo Vancomycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Do Intravaginal Devices Reduce Urinary Incontinence in Female Runners?
Status: RECRUITING
Conditions: Urinary Incontinence
Interventions: DEVICE: Pessary Intervention|DEVICE: Tampon Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Incidence of Short-term Urinary Retention After Fascial Retropubic Sling: Prospective and Randomized Analysis.
Status: UNKNOWN
Conditions: Stress Urinary Incontinence|Urinary Retention Postoperative|Urinary Retention After Procedure
Interventions: PROCEDURE: Sling tension adjustment by classic technique|PROCEDURE: Sling tension adjustment by height of 4 cm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: An Efficacy Study of Chlorhexidine Mouthwashes
Status: COMPLETED
Conditions: Gingivitis
Interventions: DRUG: Chlorhexidine Digluconate Mouthwash with Alcohol|DRUG: Chlorhexidine Digluconate Mouthwash without Alcohol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Spirulina Oral Supplement for Enhancing Host Resilience to Virus Infection
Status: RECRUITING
Conditions: Healthy Volunteers
Interventions: DIETARY_SUPPLEMENT: Immulina TM|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study Evaluating Telemonitoring and Experimentation in Telemedicine for the Improvement of Healthcare Pathways (ETAPES Program) Compared to Standard of Care in Patients With Chronic Respiratory Failure Receiving Non-invasive Home Ventilation
Status: COMPLETED
Conditions: Chronic Respiratory Failure With Hypercapnia|Chronic Obstructive Pulmonary Disease (COPD)|Obesity Hypoventilation Syndrome (OHS)
Interventions: DEVICE: ETAPES Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Analgetic Effect of Two Solutions of Intracameral Anesthesia During Cataract Surgery in Patients
Status: COMPLETED
Conditions: Cataract|Analgesia|Ophthalmological Disorder
Interventions: DRUG: lignocaine|PROCEDURE: Phacoemulsyfication|PROCEDURE: Intraocular lens implantation|BEHAVIORAL: Visual Analog Scale for Pain|BEHAVIORAL: Brief Pain Inventory-short form|DIAGNOSTIC_TEST: Best corrected visual acuity measurment|DIAGNOSTIC_TEST: Slit-lamp biomicroscopy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: CORAL - Cebranopadol Versus Morphine Prolonged-release in Patients With Chronic Moderate to Severe Pain Related to Cancer
Status: TERMINATED
Conditions: Pain|Neoplasms|Chronic Pain
Interventions: DRUG: Cebranopadol|DRUG: Morphine Prolonged Release
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multi-Gyn FloraFem Study for Treatment of Vulvo Vaginal Candidiasis Symptoms
Status: COMPLETED
Conditions: Vulvovaginal Candidiasis
Interventions: DEVICE: Multi-Gyn FloraFem
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Personalized Feedback Intervention for Alcohol and Opioid Use Among Adults With Chronic Pain
Status: RECRUITING
Conditions: Alcohol Drinking|Pain|Opioid Use|Feedback, Psychological
Interventions: BEHAVIORAL: Pain-Alcohol Personalized Feeback Intervention|BEHAVIORAL: Control Personalized Feedback Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Obesity Cohort : Medical Follow-up of Severe or Morbid Obese Patients Undergoing Bariatric Surgery
Status: RECRUITING
Conditions: Obesity, Morbid|Bariatric Surgery Candidate
Interventions: PROCEDURE: Bariatric surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Effectiveness of a Self-applied Online Program to Promote Resilience and Coping Skills in College Students
Status: UNKNOWN
Conditions: CORE Condition|Healthy Lifestyle Psychoeducational Program|Waiting List Control
Interventions: BEHAVIORAL: Cognitive Behavioral Therapy|BEHAVIORAL: Healthy lifestyle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dexpramipexole SAD/MAD Study
Status: COMPLETED
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DRUG: Dexpramipexole|DRUG: Dexpramipexole Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Investigation of Efficacy and Safety of Tree MATAMPL,Tree MATA, and Placebo in Patients With Birch-Induced Seasonal Allergic Rhinitis
Status: TERMINATED
Conditions: Type I Hypersensitivity
Interventions: BIOLOGICAL: Tree MATA MPL or Tree MATA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Telecoaching to Improve Physical Activity in Patients With Obstructive Sleep Apnea
Status: UNKNOWN
Conditions: Physical Activity|Obstructive Sleep Apnea
Interventions: OTHER: Telecoaching|DEVICE: CPAP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of BIND-014 in Patients With Urothelial Carcinoma, Cholangiocarcinoma, Cervical Cancer and Squamous Cell Carcinoma of the Head and Neck
Status: TERMINATED
Conditions: Urothelial Carcinoma|Cholangiocarcinoma|Cervical Cancer|Squamous Cell Carcinoma of Head and Neck
Interventions: DRUG: BIND-014 (docetaxel nanoparticles for injectable suspension)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ExerG: Video Game-based Physical Cognitive Training for Patients: a Usability Study
Status: RECRUITING
Conditions: Gait Disorders, Neurologic|Gait Disorders in Old Age|Gait Disorder, Sensorimotor|Balance; Distorted|Functional Movement Disorder|Visual Disorder|Cognitive Impairment
Interventions: DEVICE: ExerG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Phase I Study to Evaluate LSALT Peptide
Status: COMPLETED
Conditions: None - Study is to Determine Safety in Healthy Participants
Interventions: DRUG: LSALT peptide|OTHER: 0.9% Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study Of Healthy Subjects To Assess The Effect Of Ketoconazole And The Way The Body Will React To Casopitant [GW679769]
Status: COMPLETED
Conditions: Nausea and Vomiting, Chemotherapy-Induced
Interventions: DRUG: ketoconazole|DRUG: casopitant 100 mg|DRUG: Casopitant 50 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SGB in Management of Patients With PDPH Using TCD
Status: COMPLETED
Conditions: Post-Dural Puncture Headache
Interventions: DRUG: Sphenopalatine Ganglion Block using 2% lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Arthroscopic Anterior Cruciate Ligament Reconstruction: A Comparison of Three Catheter Placement Positions
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: DEVICE: Breg Pain Care 3000 Catheter|DRUG: Bupivicaine 0.5%|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Pharmaco-economic Study of a Second Line Treatment in Advanced Non Small Cell Lung Cancer
Status: COMPLETED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: Alimta®|DRUG: Taxotere®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Snow Properties and Its Modeling for Studying Gas Exchange Under the Simulated Avalanche Snow
Status: UNKNOWN
Conditions: Accident Caused by Snow Avalanche
Interventions: OTHER: Breathing in the simulated avalanche snow
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Acupuncture for Prevention of Radiation-Induced Xerostomia
Status: COMPLETED
Conditions: Xerostomia|Mouth Dryness|Nasopharyngeal Cancer
Interventions: PROCEDURE: Acupuncture|OTHER: Standard Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: EPIC(Effect of PhosLo on Phosphorus Levels in Chronic Kidney Disease)
Status: COMPLETED
Conditions: Hyperphosphatemia|Kidney Failure
Interventions: DRUG: calcium acetate|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Impact of Repeated Colonoscopic Insert Method on the Detection Rate of Adenomas in the Sigmoid Colon
Status: COMPLETED
Conditions: Colorectal Polyp
Interventions: PROCEDURE: secondary colonoscopy|PROCEDURE: conventional colonoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Packing of Perianal Abscess Cavities Trial: A Randomised Multicentre Trial Comparing Packing With Non-packing of the Abscess Cavity
Status: UNKNOWN
Conditions: Perianal Abscess
Interventions: OTHER: Packing of abscess cavity|OTHER: External dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: The Efficacy of Influenza Vaccine in Reducing Cardiovascular Events in Patients With Coronary Artery Diseases
Status: COMPLETED
Conditions: Coronary Artery Diseases|Myocardial Infarction|Stable Angina
Interventions: BIOLOGICAL: influenza vaccine|BIOLOGICAL: placebo for influenza vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Phase II Study of Allo-HCT for B-Cell NHL Using Zevalin, Fludarabine and Melphalan
Status: COMPLETED
Conditions: Graft Versus Host Disease|Leukemia|Lymphoma
Interventions: BIOLOGICAL: rituximab|DRUG: fludarabine phosphate|DRUG: melphalan|DRUG: sirolimus|DRUG: tacrolimus|PROCEDURE: allogeneic hematopoietic stem cell transplantation|RADIATION: indium In 111 ibritumomab tiuxetan|RADIATION: yttrium Y 90 ibritumomab tiuxetan|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Caudal Versus Intravenous Dexmedetomidine for Supplementation of Caudal Analgesia in Children
Status: COMPLETED
Conditions: Inguinal Hernia|Cryptorchidism
Interventions: DRUG: Caudal Dexmedetomidine|DRUG: Intravenous Dexmedetomidine|DRUG: Placebo|DRUG: sevoflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Clearance Of Mucus In Stents (COMIS)
Status: COMPLETED
Conditions: Lung Neoplasms|Respiratory Failure|Pneumonia|Acute Coronary Syndromes|Unstable Angina|Myocardial Infarction|Cardiac Arrhythmia|Thromboembolic Disease
Interventions: OTHER: Normal Saline|OTHER: Sodium Bicarbonate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Ketogenic Diet Adjunctive to Salvage Chemotherapy for Recurrent Glioblastoma:a Pilot Study
Status: UNKNOWN
Conditions: Glioblastoma Multiforme
Interventions: DIETARY_SUPPLEMENT: Ketogenic diet|DIETARY_SUPPLEMENT: Standard diet
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Minimizing Reperfusion Injury in Patients With Acute Myocardial Infarction
Status: SUSPENDED
Conditions: Acute Myocardial Infarction
Interventions: PROCEDURE: Post conditioning|PROCEDURE: Usual Care for STEMI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Irinotecan in Treating Children With Refractory Solid Tumors
Status: COMPLETED
Conditions: Childhood Central Nervous System Germ Cell Tumor|Childhood Choroid Plexus Tumor|Childhood Craniopharyngioma|Childhood Grade I Meningioma|Childhood Grade II Meningioma|Childhood Grade III Meningioma|Childhood Infratentorial Ependymoma|Childhood Oligodendroglioma|Childhood Supratentorial Ependymoma|Previously Treated Childhood Rhabdomyosarcoma|Recurrent Childhood Cerebellar Astrocytoma|Recurrent Childhood Cerebral Astrocytoma|Recurrent Childhood Ependymoma|Recurrent Childhood Medulloblastoma|Recurrent Childhood Rhabdomyosarcoma|Recurrent Childhood Visual Pathway and Hypothalamic Glioma|Recurrent Childhood Visual Pathway Glioma|Recurrent Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor|Recurrent Neuroblastoma|Recurrent Osteosarcoma|Unspecified Childhood Solid Tumor, Protocol Specific
Interventions: DRUG: irinotecan hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endocardial Mapping With the CoreMap EP Mapping System
Status: RECRUITING
Conditions: Persistent Atrial Fibrillation
Interventions: DEVICE: CoreMap EP Mapping System Mapping|DEVICE: CoreMap EP Mapping System Map-Guided Ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ozone Therapy in the Treatment of Digital Ulcers in Patients With Systemic Sclerosis
Status: COMPLETED
Conditions: Ulcer|Scleroderma
Interventions: DEVICE: the ozone generator device (Human Pro medic, German)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Methodology Development Environmental Clinical Trial of Reproxalap in Subjects With Seasonal Allergic Conjunctivitis
Status: COMPLETED
Conditions: Allergic Conjunctivitis
Interventions: DRUG: Reproxalap Ophthalmic Solution (0.25%)|DRUG: Reproxalap Ophthalmic Solution (0.5%)|DRUG: Vehicle Ophthalmic Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Anatomic and Visual Function Assessments on Asymptomatic HIV-positive Patients
Status: COMPLETED
Conditions: HIV Infections|Acquired Immunodeficiency Syndrome
Interventions: DEVICE: Optical Coherence Tomography (OCT)|DEVICE: Frequency Doubling Technology (FDT) perimeter
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study Assessing the Potential for Reduced Rates of Implant Failure Using Multi-Beam Intensity-Modulated Radiation Therapy for Locally Advanced Breast Cancer Patients With Implant Reconstructions
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer
Interventions: DEVICE: Breast MRI|BEHAVIORAL: Breast-Q© questionnaire|RADIATION: Multi-Beam IMRT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT