pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Telerehabilitation for the Hand and Arm After Stroke and Traumatic Brain Injury
Status: UNKNOWN
Conditions: Cerebrovascular Accident|Traumatic Brain Injury
Interventions: DEVICE: The Jerusalem Telerehabilitation System
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intercostal Cryoanalgesia for Chronic Pain After VATS Lung Resection
Status: RECRUITING
Conditions: Cryotherapy Effect|Chronic Pain|Lung Cancer|Surgery
Interventions: PROCEDURE: Cryoanalgesia AND single-injection paravertebral block|PROCEDURE: Single-injection paravertebral block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of JTX-8064, as Monotherapy and in Combination With a PD-1 Inhibitor, in Adult Subjects With Advanced Refractory Solid Tumors
Status: COMPLETED
Conditions: Cancer
Interventions: DRUG: JTX-8064|DRUG: pimivalimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stellate Ganglion Block in Children With Autistic Disorder
Status: NOT_YET_RECRUITING
Conditions: Autistic Disorder
Interventions: BEHAVIORAL: Routine therapy|PROCEDURE: Stellate ganglion block|DRUG: Lidocaine hydrochloride|BEHAVIORAL: placebo injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Efficacy of XEN-D0501 in Reducing the Cough Frequency in Patients With Chronic Idiopathic Cough
Status: COMPLETED
Conditions: Chronic Idiopathic Cough
Interventions: DRUG: XEN-D0501|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 4 Safety and Efficacy Study to Evaluate Lesinurad 200 mg in Participants With Gout and Renal Impairment
Status: TERMINATED
Conditions: Gout|Chronic Kidney Disease (CKD)
Interventions: DRUG: Lesinurad|DRUG: XOI|DRUG: Placebo|DRUG: colchicine|DRUG: corticosteroids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Mitomycin-C in Patients With Advanced or Recurrent Pancreatic Cancer With Mutated BRCA2 Gene
Status: WITHDRAWN
Conditions: Pancreatic Cancer
Interventions: DRUG: Mitomycin-C
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of MEK162 and AMG 479 in Patients With Selected Solid Tumors
Status: TERMINATED
Conditions: Metastatic Pancreatic Adenocarcinoma|BRAF Mutated Melanoma
Interventions: DRUG: MEK162|DRUG: AMG 479
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic and Safety Study of Cenicriviroc and Acid Reducing Agents When Dosed Alone or in Combination
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Cenicriviroc|DRUG: Omeprazole|DRUG: Famotidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of AIN457 in Noninfectious Uveitis
Status: COMPLETED
Conditions: Non-infectious Uveitis
Interventions: DRUG: AIN457|DRUG: AIN 457|DRUG: AIN457
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Intracanalicular Dexamethasone Compared to Loteprednol Etabonate in Patients With Keratoconus
Status: COMPLETED
Conditions: Keratoconus|Dry Eye|Allergy
Interventions: DRUG: dexamethasone ophthalmic insert 0.4 mg, for intracanalicular use|DRUG: Loteprednol Etabonate 0.38% Ophthalmic Gel/Jelly
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bedtime ACEIs/ARBs Versus Morning ACEIs/ARBs for Reverting Non-dipping Hypertension
Status: TERMINATED
Conditions: Hypertension|Non-Dipping
Interventions: DRUG: ACEi, ARB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Pain-treatment Techniques After Tympanomastoid Surgery Pain
Status: COMPLETED
Conditions: Pain Management|Nerve Block|Ultrasound
Interventions: DRUG: IV patient-controlled analgesia (PCA) tramadol|DRUG: ultrasound guided superficial cervical plexus block|DRUG: ultrasound guided Great Auricular nerve block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Evaluate the 80-Minute Water Resistant Sun Protection Factor (SPF) of Sunscreen Products
Status: COMPLETED
Conditions: Sunscreening Agents
Interventions: DRUG: CAP UnScented|DRUG: CAP Herbal Mint|DRUG: CAP Mountain Berry|DRUG: SPF Standard Sunscreen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Examine the Effect of Repeat Inhaled Doses of GW870086X on Lung Function in Mild Asthmatic Male Subjects
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: GW870086X|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Radial Artery Versus Saphenous Vein Patency (RSVP) Study
Status: COMPLETED
Conditions: Coronary Arteriosclerosis
Interventions: PROCEDURE: Coronary artery bypass graft (CABG) surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Digital Intervention to Prevent Initiation of Opioid Misuse in Adolescents in School-based Health Centers
Status: COMPLETED
Conditions: Opioid Misuse
Interventions: BEHAVIORAL: PlaySmart|BEHAVIORAL: PlaySmart Storyline|BEHAVIORAL: Play Smart Mini-Game
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Non-interventional Study (NIS) Registry for the Epidemiological and Scientific Evaluation of Epidermal Growth Factor Receptor (EGFR) Mutation Status in Patients With Newly Diagnosed Locally Advanced or Metastatic Non Small Cell Lung Cancer (NSCLC) (Stage IIIB/IV Non-small Cell Lung Cancer).
Status: COMPLETED
Conditions: Non Small Cell Lung Cancer
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Trial to Determine Effective Aspirin Dose in COPD
Status: RECRUITING
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Aspirin 81mg|DRUG: Aspirin 162 mg|DRUG: Aspirin 325mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Reciproc and Protaper Next
Status: COMPLETED
Conditions: Dental Pulp Necrosis
Interventions: PROCEDURE: Reciproc files in reciprocating motion|PROCEDURE: ProTaper Next files in continuous rotary motion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Standard Oxytocin Versus High Dose Oxytocin to Control Postpartum Hemorrhage in High Risk Pregnancy During Elective Cesarean Section
Status: NOT_YET_RECRUITING
Conditions: Post Partum Hemorrhage
Interventions: DRUG: Oxytocin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Differences Between Suicide Attempters and Suicide Ideators. Influence of the Brief Therapy Attempted Suicide Short Intervention Program (ASSIP) on Neuropsychological Correlates and Psychological Process Factors - Project 3
Status: RECRUITING
Conditions: Suicide, Attempted|Suicidal Ideation|Feasibility|Cost-effectiveness|Process Factors
Interventions: BEHAVIORAL: ASSIP (Attempted Suicide Short Intervention Program) flex
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Intravenous ZMA001 in Healthy Subjects
Status: RECRUITING
Conditions: Pulmonary Arterial Hypertension PAH
Interventions: DRUG: ZMA001 (BC-NKA-20008)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Technical Accuracy and Userfriendliness of a Point-Of-Care C Reactive Protein Device in a Nursing Home Setting
Status: COMPLETED
Conditions: Healthy Older Adults|Ill Older Adults
Interventions: DEVICE: Point-of-care test for CRP
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Breathome and Single Lead Electrocardiogram Optimizes Ischemic Heart Disease Diagnosis
Status: COMPLETED
Conditions: Coronary Artery Disease|Ischemic Heart Disease
Interventions: DIAGNOSTIC_TEST: Mass spectrometry using the PTR TOF-1000 (IONICON PTR-TOF-MS - Trace VOC Analyzer, Eduard-Bodem-Gasse 3, 6020 Innsbruck, Austria (Europe).
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Impact of Deep Neuromuscular Blockade During Total Hip Replacement Surgery on Postoperative Recovery and Immune Function
Status: RECRUITING
Conditions: Neuromuscular Blockade|Innate Inflammatory Response|Quality of Life|Postoperative Complications
Interventions: DRUG: Rocuronium Bromide|DRUG: Rocuronium Bromide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Intervention for Teens With ADHD and Substance Use
Status: TERMINATED
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: BEHAVIORAL: Brief Early Intervention|BEHAVIORAL: Parent Training with Adolescent Cognitive Behavioral Therapy|DRUG: Methylphenidate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Resistance to Methotrexate in Patients With Acute Lymphoblastic Leukemia in Relapse or Remission
Status: COMPLETED
Conditions: Leukemia
Interventions: GENETIC: microarray analysis|GENETIC: reverse transcriptase-polymerase chain reaction|OTHER: laboratory biomarker analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy of ORM-12741 for Prevention of Raynaud's Phenomenon
Status: TERMINATED
Conditions: Raynaud's Phenomenon
Interventions: DRUG: ORM-12471 30mg|DRUG: ORM-12471|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Assess the Efficacy and Safety of OBE2109 in Subjects With Endometriosis
Status: COMPLETED
Conditions: Endometriosis
Interventions: DRUG: Placebo|DRUG: OBE2109
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study on the Effect of Chemotherapy Combined With Anti-HIV Drugs in HIV-Positive Patients
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Nelfinavir mesylate|DRUG: Lamivudine|DRUG: Filgrastim|DRUG: Stavudine|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Esophagectomy With or Without Prior Ischemic Gastric Preconditioning
Status: TERMINATED
Conditions: Esophageal Cancer
Interventions: PROCEDURE: Two Stage Esophagectomy|PROCEDURE: One Stage Esophagectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Static Lung Hyperinflation and Sympathetic Nerve Activity-Associated Large Artery Stiffness in COPD Patients
Status: COMPLETED
Conditions: COPD
Interventions: DRUG: Umeclidinium / Vilanterol Dry Powder Inhaler|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Oxygenation and Pulmonary Function in Morbidly Obese Patients Undergoing Bariatric Surgery
Status: UNKNOWN
Conditions: Morbid Obesity
Interventions: DEVICE: Boussignac TM CPAP|DEVICE: Venturi Face Mask
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Laparoscopic Reinforcement Suture (LARS) of Duodenal Stump A Prospective Single Arm Phase II Study
Status: UNKNOWN
Conditions: Duodenal Stump Leak
Interventions: PROCEDURE: Laparoscopic reinforcement suture
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Action Observation Therapy and Motor Imagery Administered During Immobilization Period After Surgical Fixation of Distal Radius
Status: RECRUITING
Conditions: Distal Radius Fracture
Interventions: BEHAVIORAL: Motor Imagery and Action Observation Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Raltegravir Insulin Sensitivity Study
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Raltegravir then lopinavir/ritonavir|DRUG: Lopinavir/ritonavir then raltegravir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Randomized Study of Nimodipine Versus Magnesium Sulfate in the Prevention of Eclamptic Seizures in Patients With Severe Preeclampsia
Status: COMPLETED
Conditions: Pre-eclampsia
Interventions: DRUG: magnesium sulfate|DRUG: nimodipine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: PREVENTION
Clinical trial: Clinical Trial of Gut Microbiota in the Management of Immune Thrombocytopenia
Status: UNKNOWN
Conditions: Immune Thrombocytopenia
Interventions: DRUG: Probiotic Agent|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Extracorporeal Shockwave Myocardial Revascularization
Status: UNKNOWN
Conditions: Refractory Angina Pectoris
Interventions: DEVICE: device for Extracorporeal Shockwave Myocardial Revascularization (ESMR) therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Enhancing Lung Health in Kids With Structural Lung Damage and Malformations: Azithromycin (AZI) for Airway Infection Prevention
Status: NOT_YET_RECRUITING
Conditions: Tracheomalacia|Bronchopulmonary Dysplasia (BPD)|Vascular Ring|Cystic Lung Disease|Bronchiectasis|Chronic Atelectasis
Interventions: DRUG: Azithromycin 40 MG/ML|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Canola-Mediterranean Diet Study in T2DM
Status: COMPLETED
Conditions: Type 2 Diabetes|Obesity|Overweight|Cardiovascular Diseases
Interventions: BEHAVIORAL: A canola oil enriched mediterranean diet|BEHAVIORAL: A high wheat fiber diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Correcting Anemia and Native Vitamin D Supplementation in Kidney Transplant Recipients
Status: TERMINATED
Conditions: Kidney Transplantation|Anemia|Vitamin D Deficiency|Renal Insufficiency, Chronic
Interventions: OTHER: High Hb target|DIETARY_SUPPLEMENT: cholecalciferol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics and Safety Study of Tipranavir in Combination With Low Dose Ritonavir in Human Immunodeficiency Virus (HIV)-Infected Children
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: TPV oral solution|DRUG: TPV oral solution|DRUG: RTV oral solution|DRUG: RTV oral solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low Intensity Shock-wave Therapy (Li-ESWT) in Penile Rehabilitation After Radical Prostatectomy
Status: RECRUITING
Conditions: Erectile Dysfunction Following Radical Prostatectomy
Interventions: DEVICE: Extra-corporeal shockwave therapy (ESWT)|OTHER: Standard care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Integrated Boost to the Dominant Intraprostatic Nodule Based on Ga-68 PSMA PET/MR Study of SBRT With Prostate Cancer
Status: UNKNOWN
Conditions: Treatment
Interventions: RADIATION: Stereotactic Body Radiation Therapy (SBRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Examine the Pharmacodynamic Effects of GSK1034702 on Neurophysiological Biomarkers of Cognition in Nicotine Abstained Otherwise Healthy Smokers
Status: COMPLETED
Conditions: Mental Disorders
Interventions: DRUG: Drug|DRUG: Drug
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Trans-anal Eco-doppler Evaluation of Haemorrhoidal Vascularization After Percutaneous Hemorrhoidal Artery Embolization. A Pilot Study.
Status: RECRUITING
Conditions: Haemorrhoidal Bleeding
Interventions: PROCEDURE: doppler endoanal ultrasound
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Vestibular Extraction Technique (VET): a Novel Atraumatic Extraction Technique
Status: COMPLETED
Conditions: Tooth Extraction
Interventions: PROCEDURE: Vestibular Root Extraction|PROCEDURE: Atraumatic extractions using periotomes followed by conventional forceps
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Impact of Reactivation During Sleep on the Consolidation of Abstract Information in Humans
Status: COMPLETED
Conditions: Memory Consolidation
Interventions: BEHAVIORAL: Congruent vs. Incongruent|BEHAVIORAL: Immediate vs. Awake vs. Asleep|BEHAVIORAL: Targeted memory reactivation (TMR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study to Examine Effect of Recombinant Luteinizing Hormone (r-Lh) and Recombinant Human Chorionic Gonadotropin (r-hCG) for Ovarian Stimulation in Assisted Reproduction Techniques (ART)
Status: COMPLETED
Conditions: Controlled Ovarian Stimulation|Infertility
Interventions: DRUG: recombinant luteinizing hormone (r-LH)|DRUG: recombinant human chorionic gonadotropin (r-hCG)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of Avastin (Bevacizumab) and Transarterial Chemoembolisation (TACE) Treatment in Patients With Liver Cancer
Status: COMPLETED
Conditions: Liver Cancer
Interventions: DRUG: Bevacizumab|PROCEDURE: Transarterial chemoembolisation (TACE)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Determine Safety and Tolerability of GMI-1359 in Subjects With HR+ Metastatic Breast Cancer
Status: TERMINATED
Conditions: HR+ Metastatic Breast Cancer|Breast Cancer|Breast Cancer Metastatic
Interventions: DRUG: GMI-1359
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of SH T00658ID as Compared to a Monophasic Contraceptive Containing Ethinylestradiol and Levonorgestrel (SH D01155E) on Hemostatic Parameters
Status: COMPLETED
Conditions: Pregnancy, Unplanned
Interventions: DRUG: EV/DNG (Qlaira, BAY86-5027, SH T00658ID)|DRUG: SH D01155E
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effects of Whole Body Vibration in Pre-frail Individuals Over 65 Years of Age: Randomized Clinical Trial
Status: ENROLLING_BY_INVITATION
Conditions: Pre-frail
Interventions: OTHER: Whole body vibration|OTHER: The exercise program on flat ground without a vibration platform
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Experimental Medicine in ADHD - Cannabinoids
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder (ADHD)
Interventions: DRUG: Sativex Oromucosal Spray|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Trial of a Gastrin Receptor Antagonist in Barrett's Esophagus
Status: COMPLETED
Conditions: Barrett's Esophagus
Interventions: DRUG: YF476|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Nanoparticle Albumin-Bound (Nab) Paclitaxel/Cyclophosphamide in Early-Stage Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: nab paclitaxel|DRUG: Cyclophosphamide|DRUG: Trastuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transcatheter Arterial Chemoembolization Combined With Sorafenib for Unresectable Hepatocellular Carcinoma
Status: COMPLETED
Conditions: Hepatocellular Carcinoma|Face Cancer
Interventions: PROCEDURE: TACE-Sorafenib group|PROCEDURE: TACE
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics of Oral Morphine and Pharmacogenomics of CYP2D6 and UGT2B7, in an Urban Pediatric Population Presenting for Elective Surgery
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Morphine|DRUG: Morphine|DRUG: Morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effects of Paired Associative Nerve Stimulation on Spinal Cord Injury Subjects
Status: RECRUITING
Conditions: Spinal Cord Injuries
Interventions: DEVICE: 20 Hz rTMS (Brain)|DEVICE: iTBS rTMS (Brain)|DEVICE: Anode tsDCS (Spinal)|DEVICE: 20 Hz current square-wave pulses (Spinal)|DEVICE: iTBS (Spinal)|DEVICE: sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Carbetocin Versus Syntometrine in Obese Women Undergoing Elective Cesarean
Status: COMPLETED
Conditions: Post Partum Hemorrhage
Interventions: DRUG: carbetocin|DRUG: Syntometrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Therapeutic Education Consultations With Diabetic Patients Treated With Intensified Insulin Therapy
Status: RECRUITING
Conditions: Diabete Mellitus|Insulin Dependent Diabetes
Interventions: OTHER: Diabetes Therapeutic Education conducted by nurses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of Revumenib in R/R Leukemias Including Those With an MLL/KMT2A Gene Rearrangement or NPM1 Mutation
Status: RECRUITING
Conditions: Acute Myeloid Leukemia|Acute Lymphoblastic Leukemia|Mixed Lineage Acute Leukemia|Mixed Phenotype Acute Leukemia|Acute Leukemia of Ambiguous Lineage
Interventions: DRUG: revumenib|DRUG: cobicistat
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of ONTAK (Denileukin Diftitox) in Cutaneous T-Cell Lymphoma (CTCL) Patients
Status: COMPLETED
Conditions: Lymphoma, T-Cell, Cutaneous|Mycosis Fungoides|Sezary Syndrome
Interventions: DRUG: ONTAK
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Home Infusors for Analgesia After Foot Surgery
Status: UNKNOWN
Conditions: Hallux Valgus
Interventions: PROCEDURE: elastomeric pump with reservoir of 500 ml, infusion rate of 8 ml/h|PROCEDURE: elastomeric pump with reservoir of 275 ml, infusion rate of 5 ml/h
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Flow-flow ECCO2-R and 4 ml/kg Tidal Volume vs. 6 ml/kg Tidal Volume to Enhance Protection From VILI in Acute Lung Injury
Status: TERMINATED
Conditions: Acute Respiratory Distress Syndrome
Interventions: OTHER: ARDS-Net Strategy|OTHER: ECCO2-R
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Immunotherapy Plus Standard-of-Care Chemotherapy Versus Standard-of-Care Chemotherapy for the Treatment of Locally Advanced or Metastatic Pancreatic Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Pancreatic Cancer
Interventions: BIOLOGICAL: N-803|DRUG: Aldoxorubicin HCl|BIOLOGICAL: PD-L1 t-haNK|DRUG: Nab-paclitaxel|DRUG: Gemcitabine|DRUG: Cyclophosphamide|DRUG: 5-Fluorouracil|DRUG: Leucovorin|PROCEDURE: SBRT|DRUG: Irinotecan liposome
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: APIOC for Presbyopia and APIOC for Presbyopia With Astigmatism
Status: COMPLETED
Conditions: Presbyopia|Myopia|Hyperopia|Astigmatism
Interventions: DEVICE: APIOC for Presbyopia and APIOC for Presbyopia for Astigmatism
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intraoperative Dual-modality Imaging in Renal Cell Carcinoma
Status: UNKNOWN
Conditions: Carcinoma, Renal Cell
Interventions: DRUG: Indium-111-DOTA-Girentuximab-IRDye800CW|RADIATION: SPECT/CT|PROCEDURE: Intraoperative dual-modality imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: An Observational Study of The Safety of MabThera/Rituxan (Rituximab) in Participants With Granulomatosis With Polyangiitis (Wegener's) or Microscopic Polyangiitis
Status: COMPLETED
Conditions: Granulomatosis With Polyangiitis|Microscopic Polyangiitis
Interventions: DRUG: Rituximab
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study Evaluating the Treatment of OTX-TKI for Subjects With Neovascular Age-related Macular Degeneration
Status: COMPLETED
Conditions: Neovascular Age-Related Macular Degeneration
Interventions: DRUG: OTX-TKI/Sham|DRUG: Aflibercept/Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Stay Well at Home: a Text-messaging Study Social Distancing
Status: COMPLETED
Conditions: Depressive Symptoms|Anxiety|COVID-19
Interventions: BEHAVIORAL: Uniform random message delivery|BEHAVIORAL: Reinforcement learning message delivery|BEHAVIORAL: Mood ratings only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Panitumumab and Irinotecan as Third-Line Therapy in Treating Patients With Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: Panitumumab|DRUG: Irinotecan hydrochloride|GENETIC: Chromogenic in situ hybridization|GENETIC: Fluorescence in situ hybridization|GENETIC: Gene expression analysis|OTHER: Laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Safety of Intravesical Hyaluronic Acid and Chondroitin Sulfate After Transurethral Resection of Hunner Lesion in Interstitial Cystitis/Bladder Pain Syndrome Patients
Status: COMPLETED
Conditions: Interstitial Cystitis
Interventions: DRUG: Hyaluronic Acid and Chondroitin Sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Deep Biopsy Via Endoscopic Submucosal Dissection in Upper GI Subepithelial Tumors
Status: UNKNOWN
Conditions: Benign Neoplasm|Pathology
Interventions: PROCEDURE: deep biopsy via ESD technique
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparision Efficacy of Carbamazepine & Oxcarbazepine in the Treatment of Trigeminal Neuralgia- a Randomised Clinical Trial
Status: UNKNOWN
Conditions: Trigeminal Neuralgia
Interventions: DRUG: Oxcarbazepine|DRUG: Carbamazepine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of Protein Supplementation in Attenuating the Decline in Performance After Strenuous Concurrent Exercise
Status: COMPLETED
Conditions: Sports Nutritional Sciences
Interventions: DIETARY_SUPPLEMENT: Test product|DIETARY_SUPPLEMENT: Reference product 1|DIETARY_SUPPLEMENT: Reference product 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Durvalumab + Tremelimumab in NSCLC Patients After Adjuvant Treatment
Status: WITHDRAWN
Conditions: Nonsmall Cell Lung Cancer
Interventions: DRUG: Durvalumab|DRUG: Tremelimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effects of Different Analgesics on Pericoronitis Pain and Quality of Life
Status: COMPLETED
Conditions: Pain|Quality of Life
Interventions: DRUG: Diclofenac|DRUG: Flurbiprofen|DRUG: Benzydamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Testosterone Treatment for Hypogonadal Men
Status: COMPLETED
Conditions: Hypogonadism
Interventions: DRUG: Testosterone (T) Gel 1.62%|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of SH T00660AA in Treatment of Endometriosis
Status: COMPLETED
Conditions: Endometriosis
Interventions: DRUG: Visanne (BAY86-5258, SH T00660AA)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of a Food Supplement on Quality of Life in Patients With Chronic Obstructive Pulmonary Disease.
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DIETARY_SUPPLEMENT: Food supplement|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Deferred Cord Clamping Compared to Umbilical Cord Milking in Preterm Infants
Status: UNKNOWN
Conditions: PreTerm Birth|Intraventricular Hemorrhage
Interventions: OTHER: Umbilical cord milking
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of Intra-operative Radiotherapy With Post-operative Radiotherapy for Women With Ductal Carcinoma in Situ
Status: UNKNOWN
Conditions: Breast Neoplasms
Interventions: RADIATION: Intraoperative Radiotherapy|RADIATION: Whole breast radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility and Acceptability of Group Pain Reprocessing Therapy for Veterans With Chronic Neck/Back Pain
Status: RECRUITING
Conditions: Chronic Back Pain|Chronic Pain|Neck Pain|Back Pain
Interventions: BEHAVIORAL: Pain Reprocessing Therapy (PRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nabilone Versus Amitriptyline in Improving Quality of Sleep in Patients With Fibromyalgia
Status: COMPLETED
Conditions: Fibromyalgia|Sleep Initiation and Maintenance Disorders
Interventions: DRUG: Amitriptyline Hydrochloride|DRUG: Nabilone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Local Anesthesia and Analgesics in Endodontic Pain
Status: WITHDRAWN
Conditions: Odontalgia
Interventions: DRUG: Oral placebo|DRUG: Oral ibuprofen|DRUG: oral naproxen|DRUG: oral acetaminophen/hydrocodone + ibuprofen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Tolerability Assessment Study of Three Wash Products in Infants
Status: COMPLETED
Conditions: Skin Care
Interventions: OTHER: Test shampoo|OTHER: Test bath foam|OTHER: Test head to toe wash
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Zortress® + Tacrolimus vs. Standard Immunosuppression on Progression of Coronary Artery Calcifications and Bone Disease in de Novo Renal Transplant Recipients
Status: WITHDRAWN
Conditions: Renal Transplant
Interventions: DRUG: Zortress® /Everolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Promoting Caregiver-child Attachment and Recovery Through Early Intervention (pCARE): A Pilot Randomized Control Trial
Status: COMPLETED
Conditions: Opioid-use Disorder|Substance Use Disorders|Parenting
Interventions: BEHAVIORAL: pCARE|OTHER: Standard Early Intervention services
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Clinical and Radiographical Analysis of the Distal Radioulnar Joint Following Implantation of a Scheker Total Distal Radioulnar Joint Prosthesis
Status: COMPLETED
Conditions: Scheker Total Distal Radioulnar Joint Prosthesis
Interventions: PROCEDURE: Implantation of a Scheker total distal radioulnar joint prosthesis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Help People Quit Smoking.
Status: COMPLETED
Conditions: Nicotine Dependence
Interventions: DRUG: placebo|DRUG: Galantamine 8mg|DRUG: Galantamine 16mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of KNO3 Compared to KCl on Oxygen UpTake in Heart Failure With Preserved Ejection Fraction (KNO3CK OUT HFPEF)
Status: COMPLETED
Conditions: Heart Failure
Interventions: DRUG: Potassium Nitrate (KNO3)|DRUG: Potassium Chloride (KCl)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Back 2 School Program in a Norwegian Setting: A Multicenter Pilot Study
Status: COMPLETED
Conditions: Absence|School Phobia|Truancy; Socialized|Depression, Anxiety
Interventions: BEHAVIORAL: The Back 2 School program for problematic school absenteeism
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chitosan-Hyaluronate Gel Mixture Vs Hyaluronic for Internal Derangement
Status: RECRUITING
Conditions: TMJ Disc Disorder
Interventions: DRUG: Chitosan-Hyaluronate Gel Mixture|DRUG: Hyaluronic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Body Temperature Changes and Early Postoperatıve Pressure Sore
Status: COMPLETED
Conditions: Pressure Sore|Orthopedic Disorder|Hypothermia|Nursing Caries
Interventions: PROCEDURE: woolen blanket
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Peripheral Stem Cell Transplantation Plus Combination Chemotherapy in Treating Patients With Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma and Plasma Cell Neoplasm
Interventions: DRUG: carmustine|DRUG: cisplatin|DRUG: cyclophosphamide|DRUG: dexamethasone|DRUG: etoposide|DRUG: melphalan|DRUG: paclitaxel|PROCEDURE: in vitro-treated peripheral blood stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: A Cardiosleep Research Program on Obstructive Sleep Apnea, Blood Pressure Control and Maladaptive Myocardial Remodeling
Status: COMPLETED
Conditions: Hypertension,Essential|Obstructive Sleep Apnea
Interventions: DEVICE: Mandibular Advancement Device|DEVICE: Continuous Positive Airway Pressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of SIMBRINZA® Suspension as an Added Therapy to TRAVATAN Z®
Status: COMPLETED
Conditions: Ocular Hypertension|Open Angle Glaucoma
Interventions: DRUG: Brinzolamide 1%/brimonidine 0.2% ophthalmic suspension|DRUG: Vehicle|DRUG: Travoprost 0.004% ophthalmic solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Adjuvant Low Dose Aspirin in Colorectal Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Colorectal Cancer
Interventions: DRUG: Acetylsalicylic acid|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dysport® Adult Upper Limb Spasticity
Status: COMPLETED
Conditions: Nervous System Disorders
Interventions: BIOLOGICAL: Botulinum toxin type A|BIOLOGICAL: Botulinum toxin type A|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study of 6MW3211 Monotherapy or Combination Therapy for AML or MDS
Status: RECRUITING
Conditions: Acute Myeloid Leukemia|Myelodysplastic Syndrome
Interventions: DRUG: 6MW3211 injection with Intravenous Infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of AZD8233 in Participants With Dyslipidemia
Status: COMPLETED
Conditions: Dyslipidaemia
Interventions: DRUG: AZD8233|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combined Effect of Foam Roller and Gastrocnemius Release on Plantar Fasciitis
Status: NOT_YET_RECRUITING
Conditions: Plantar Fascitis
Interventions: OTHER: gastrocnemius release|OTHER: conventional treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate, Safety, Tolerability, Pharmacodynamic (PD) Markers and Pharmacokinetics (PK) of AP-101 in Participants With Amyotrophic Lateral Sclerosis (ALS)
Status: ACTIVE_NOT_RECRUITING
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DRUG: AP-101|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Efficacy and Safety of T1225 Versus Tobramycin 0.3 % Eye Drops in the Treatment of Purulent Bacterial Conjunctivitis of Children.
Status: COMPLETED
Conditions: Purulent Bacterial Conjunctivitis
Interventions: DRUG: T1225|DRUG: Tobramycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Oncolytic Virus Ad-TD-nsIL12 for Progressive Pediatric Diffuse Intrinsic Pontine Glioma
Status: RECRUITING
Conditions: Oncolytic Virus|Diffuse Intrinsic Pontine Glioma|Adverse Drug Event
Interventions: BIOLOGICAL: Ad-TD-nsIL12
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chronic Transcutaneous Stimulation to Promote Motor Function and Recovery in Individuals With Paralysis or Paresis
Status: RECRUITING
Conditions: Healthy Volunteers|Spinal Cord Injury|Stroke|Paralysis|Paresis|Neurological Injury
Interventions: DEVICE: Transcutaneous Electrical Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Efficacy and Safety of a Fungal Chitosan on the Body Weight Reduction in Overweight and Obesity Volunteers
Status: COMPLETED
Conditions: Overweight and Obese Volunteers.
Interventions: DEVICE: KiOnutrime®-Cs|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Oral Prednisolone for Acute Rhinovirus Induced Wheezing in Children Less Than 2 Years of Age
Status: RECRUITING
Conditions: Bronchiolitis Acute Viral
Interventions: DRUG: Prednisolone Sodium Phosphate|DRUG: Sugar syrup
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of OROS Oybutynin and TTS Oxybutynin in Middle-Aged and Elderly Women With Urinary Incontinence
Status: COMPLETED
Conditions: Urinary Incontinence
Interventions: DRUG: Oxybutynin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Observational Study of Type 2 Diabetes Patients Failing on Oral Anti-diabetic Agents Initiated on Levemir® or Insulatard®
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: insulin detemir|DRUG: insulin NPH
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects on Septic Patient's Microcirculation of the Transfusion of Different Types of Concentrated RBCs.
Status: COMPLETED
Conditions: Septic Patients
Interventions: BIOLOGICAL: Blood transfusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Alternate Day Versus Daily Oral Iron Therapy in Adolescents
Status: COMPLETED
Conditions: Iron Deficiency Anemia|Heavy Menstrual Bleeding|Abnormal Uterine Bleeding
Interventions: DRUG: Ferrous sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Impact of Early Enteral vs. Parenteral Nutrition on Mortality in Patients Requiring Mechanical Ventilation and Catecholamines
Status: TERMINATED
Conditions: Acute Respiratory Failure|Shock
Interventions: OTHER: Enteral nutrition|OTHER: Parenteral nutrition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Healing Chronic Venous Stasis Wounds With Autologous Cell Therapy
Status: UNKNOWN
Conditions: Wound, Nonpenetrating
Interventions: DEVICE: Transpose ® RT System|OTHER: debridement/dressing of wound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Extension Study to Evaluate the Long-Term Efficacy and Safety of BMN 190 in Patients With CLN2 Disease
Status: COMPLETED
Conditions: Jansky-Bielschowsky Disease|Batten Disease|Late-Infantile Neuronal Ceroid Lipofuscinosis Type 2|CLN2 Disease|CLN2 Disorder
Interventions: BIOLOGICAL: BMN 190|DEVICE: Intracerebroventricular (ICV) access device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cranial Osteopathic Manipulative Medicine as an Adjunct Treatment for Concussion
Status: COMPLETED
Conditions: Concussion Injury of Cerebrum|Cranial Osteopathic Medicine
Interventions: OTHER: Cranial Osteopathic Manipulative Medicine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT