pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Study to Evaluate the Efficacy and Safety of Birtamimab in Mayo Stage IV Patients With AL Amyloidosis
Status: RECRUITING
Conditions: Light Chain (AL) Amyloidosis
Interventions: DRUG: Birtamimab|OTHER: Placebo|DRUG: Standard of Care Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Does DNA Sperm Fragmentation Affects Embryo Morphokinetic?
Status: TERMINATED
Conditions: Blastocyst Time|Pronuclear Appearance|Pronuclear Fading|Embryo Compaction|Cleavage Times
Interventions: OTHER: MACS
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Tenofovir Versus Tenofovir + Telbivudine for Chronic Hepatitis B
Status: UNKNOWN
Conditions: Chronic Hepatitis B
Interventions: DRUG: Tenofovir disoproxil|DRUG: Telbivudine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Safety and Effectiveness of Using Ultrasound Scalpel to Coagulate 5-7mm Blood Vessels : a Prospective, Multicenter Clinical Trial
Status: COMPLETED
Conditions: The Safety of Ultrasound Knife Coagulation for Blood Vessels With a Diameter Greater Than 5mm and Less Than or Equal to 7mm
Interventions: DEVICE: Occlusion of blood vessels with a diameter greater than 5mm and less than or equal to 7mm using harmonic scalpel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of NH004 Films for Relief of Sialorrhea Symptoms in Parkinson's Disease Patients
Status: COMPLETED
Conditions: Sialorrhea Secondary to Parkinson's Disease
Interventions: DRUG: 0.3 mg tropicamide|DRUG: 1 mg tropicamide|DRUG: 3 mg tropicamide|DRUG: 0 mg tropicamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Single Doses of Indacaterol Delivered Via a Single Dose Dry Powder Inhaler (SDDPI) Compared to Placebo in Patients With Persistent Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: indacaterol maleate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Dose Reduction Immunobridging and Safety Study of Two HPV Vaccines in Tanzanian Girls
Status: ACTIVE_NOT_RECRUITING
Conditions: Human Papilloma Virus
Interventions: DRUG: bivalent HPV vaccine|DRUG: nonavalent HPV vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of Dexlansoprazole MR Compared to Placebo on Maintaining Healing in Subjects With Healed Erosive Esophagitis
Status: COMPLETED
Conditions: Esophagitis, Reflux|Esophagitis, Peptic
Interventions: DRUG: Dexlansoprazole MR|DRUG: Dexlansoprazole MR|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Medical Student Firearm Safety Counseling Follow-Up Study
Status: RECRUITING
Conditions: Medical Student Knowledge of Firearm Violence Epidemiology|Medical Student Knowledge About Firearm Safety Procedures|Medical Student-initiated Clinical Firearm Safety Counseling
Interventions: BEHAVIORAL: Expanded Clinical Firearm Safety Counseling Training
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: PMMA vs Polysulfone in SARS-CoV-2 Infection Hemodialysis Patients
Status: UNKNOWN
Conditions: SARS-CoV-2 Infection
Interventions: DEVICE: PS membrane versus PMMA membrane,
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: RC88 in Platinum-Resistant Recurrent Epithelial Ovarian Cancer, Fallopian Tube Cancer, and Primary Peritoneal Cancer
Status: RECRUITING
Conditions: Primary Peritoneal Cancer|Fallopian Tube Cancer|Epithelial Ovarian Cancer
Interventions: DRUG: RC88
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Temozolomide and Irinotecan Hydrochloride With or Without Bevacizumab in Treating Young Patients With Recurrent or Refractory Medulloblastoma or CNS Primitive Neuroectodermal Tumors
Status: COMPLETED
Conditions: Central Nervous System Neoplasm|Pineoblastoma|Recurrent Medulloblastoma|Recurrent Primitive Neuroectodermal Tumor|Refractory Medulloblastoma|Refractory Peripheral Primitive Neuroectodermal Tumor
Interventions: BIOLOGICAL: Bevacizumab|DRUG: Irinotecan Hydrochloride|DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of FIFA 11+ With Dynamic Core Stability Training on Balance and Dynamic Knee Valgus in Amateur Soccer Players
Status: UNKNOWN
Conditions: Injury Prevention|Postural Balance
Interventions: OTHER: FIFA 11+ protocol with additional Core training exercises|OTHER: FIFA 11+ protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing the Effectiveness and Safety of Teriflunomide and Interferon Beta-1a in Patients With Relapsing Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DRUG: Interferon β-1a|DRUG: Teriflunomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Platelet Function After Administration of Aspirin Versus Lysine Acetylsalicylate
Status: COMPLETED
Conditions: Adverse Effect of Antithrombotic Drugs
Interventions: DRUG: acetylsalicylic acid|DRUG: prasugrel|DRUG: lysine acetylsalicylate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SpO2 Difference Between Fingers of the Hand During Sequential Desaturation and Step Resaturation
Status: ENROLLING_BY_INVITATION
Conditions: Hypoxia|Pulse Oximetry|SpO2
Interventions: OTHER: Breathing mixtures of O2 and N2 and monitoring SpO2 on each finger
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Cilengitide in Treating Patients With Metastatic Prostate Cancer
Status: COMPLETED
Conditions: Recurrent Prostate Cancer|Stage IV Prostate Cancer
Interventions: DRUG: cilengitide|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single Dose Versus Two Weeks Course of Fluconazole in the Treatment of Oropharyngeal Candidiasis in HIV Infected Individuals in Tanzania
Status: COMPLETED
Conditions: Oropharyngeal Candidiasis
Interventions: DRUG: fluconazole|DRUG: fluconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II Trial of Oral Vinorelbine in Children With Recurrent or Progressive Unresectable Low-Grade Glioma
Status: COMPLETED
Conditions: Low-Grade Glioma
Interventions: DRUG: ORAL VINORELBINE
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Changes in Estrogen Levels and Grip Strength in Postmenopausal Women Who Have Received 4 to 6 Years of Hormone Therapy for Breast Cancer and Are Currently Receiving Letrozole on Clinical Trial IBCSG-35-07
Status: COMPLETED
Conditions: Breast Cancer
Interventions: GENETIC: polymorphism analysis|OTHER: laboratory biomarker analysis|PROCEDURE: quality-of-life assessment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pexelizumab in Conjunction With Angioplasty in Acute Myocardial Infarction (APEX-AMI)
Status: COMPLETED
Conditions: Acute Myocardial Infarction
Interventions: DRUG: Pexelizumab|DRUG: Placebo infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of PP-01 on Cannabis Withdrawal Syndrome
Status: COMPLETED
Conditions: Cannabis Withdrawal
Interventions: COMBINATION_PRODUCT: PP-01 High Dose|COMBINATION_PRODUCT: PP-01 Low Dose|DRUG: Placebo|DRUG: Nabilone|DRUG: Gabapentin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Utility of Exercise-induced N-terminal (NT) Pro-brain Natriuretic Peptide Levels in Predicting Prognosis in Asymptomatic Aortic Stenosis
Status: TERMINATED
Conditions: Aortic Stenosis
Interventions: OTHER: NT-pro-BNP levels
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Pelvic Varicose Veins Treated With Vascular Plugs Type Amplatzer: REPiVAC
Status: UNKNOWN
Conditions: Pelvic Congestion Syndrome|Pelvic Varicose Veins|Follow-up Study|Embolization, Therapeutic|Observational Study
Interventions: DEVICE: pelvic varicose veins plug embolization
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Pilot Study of Virtual Reality and Antigravity Treadmill for Gait Improvement in Parkinson
Status: COMPLETED
Conditions: Parkinson Disease|Gait Disorders, Neurologic
Interventions: OTHER: Virtual reality combined with anti-gravity treadmill
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hypoxia-positron Emission Tomography (PET) and Intensity Modulated Proton Therapy (IMPT) Dose Painting in Patients With Chordomas
Status: COMPLETED
Conditions: Chordoma
Interventions: PROCEDURE: Fluoromisonidazole-PET/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Sparing Diaphragm; ISO Block Versus Low Volume Scalene Block
Status: UNKNOWN
Conditions: Shoulder Arthropathy Associated With Other Conditions
Interventions: PROCEDURE: scalene block|PROCEDURE: ISO block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Drug Use Investigation of Xofigo, Castration Resistant Prostate Cancer With Bone Metastases
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostatic Neoplasms, Castration-Resistant
Interventions: DRUG: Radium-223 dichloride (Xofigo, BAY 88-8223)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Multicenter Study on the Efficacy and Safety of OCS-01 in Subjects With Uveitis Related and Post Surgical Macular Edema
Status: RECRUITING
Conditions: Uveitis Related Cystoid Macular Edema|Cystoid Macular Edema, Postoperative
Interventions: DRUG: OCS-01
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Decitabine Plus CHOP vs CHOP in Patients With Untreated Peripheral T-Cell Lymphoma
Status: UNKNOWN
Conditions: Peripheral T-cell Lymphoma
Interventions: DRUG: Decitabine|DRUG: Cyclophosphamide|DRUG: Doxorubicin|DRUG: Vincristine|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects Of Rehabilitation Incorporating Gait Training On Clinical Measures Associated With Chronic Ankle Instability
Status: COMPLETED
Conditions: Chronic Ankle Instability
Interventions: OTHER: Traditional Instability Tools|OTHER: Ankle Destabilization Shoes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Superficial Lesions in the Peri-auricular Region
Status: COMPLETED
Conditions: Superficial Cyst or Mass and Sinus on and Around the Ear
Interventions: PROCEDURE: Complete excision to superficial lesions around the ear
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Allogeneic NKG2DL-targeting CAR γδ T Cells (CTM-N2D) in Advanced Cancers
Status: UNKNOWN
Conditions: Cancer|Malignancy|Refractory Cancer|Relapsed Cancer
Interventions: BIOLOGICAL: Allogeneic NKG2DL-targeting Chimeric Antigen Receptor-grafted γδ T Cells (CTM-N2D)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 1b/2a Trial to Evaluate LEP-F1 + GLA-SE in Healthy Adults and Leprosy Patients
Status: NOT_YET_RECRUITING
Conditions: Leprosy
Interventions: BIOLOGICAL: LEP-F1 + GLA-SE|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Association of Keratinised Mucosa Around Implants and Teeth With Peri-implant/Periodontal Disease and Soft Tissue Conditioning
Status: COMPLETED
Conditions: Peri-Implantitis|Soft Tissue|Bone Gain
Interventions: PROCEDURE: Free gingival graft obtained from the palate and debridement of the peri-implant lesion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Alleviation by Fisetin of Frailty, Inflammation, and Related Measures in Older Women
Status: ENROLLING_BY_INVITATION
Conditions: Frail Elderly Syndrome
Interventions: DIETARY_SUPPLEMENT: Fisetin|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness and Safety of Combination of Nebivolol and Amlodipine in Hypertensive Patients Versus Each Monotherapy
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Nebivolol|DRUG: Amlodipine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Superficial Cervical Plexus Block for Postoperative Chronic Pain
Status: COMPLETED
Conditions: Neurosurgery
Interventions: PROCEDURE: Superficial cervical plexus block|OTHER: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Symphysis Onlay Bone Graft, Injectable Platelet Rich Fibrin (I-PRF) and Xenograft on Horizontal Alveolar Ridge Augmentation in Esthetic Zone
Status: COMPLETED
Conditions: Symphysis Onlay Bone Graft|Platelet Rich Fibrin|Xenograft|Horizontal Alveolar Ridge Augmentation|Esthetic Zone
Interventions: OTHER: Injectable Platelet Rich Fibrin|OTHER: Xenograft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Exploratory Non Comparative Study to Evaluate the Efficacy of Highly Bioavailable Curcumin (Flexofytol) in Patients With Knee Osteoarthritis
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: DIETARY_SUPPLEMENT: Flexofytol (bio-optimized curcumin)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pivotal Study of an Antimicrobial Wound Dressing to Treat Chronic Wounds
Status: COMPLETED
Conditions: Pressure Injury|Venous Leg Ulcer|Pressure Injury Stage 2|Pressure Injury Stage III|Diabetic Foot Ulcer|Pressure Injury Stage IV|Leg Ulcer
Interventions: DEVICE: NanoSALV Catalytic
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study Evaluating SB-751689 in Post-Menopausal Women With Osteoporosis.
Status: TERMINATED
Conditions: Osteoporosis
Interventions: DRUG: Ronacaleret|DRUG: Teriparatide|DRUG: Alendronate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Use of Sodium Bicarbonate in the Prevention of Contrast Induced Nephropathy
Status: TERMINATED
Conditions: Contrast Induced Nephropathy
Interventions: DRUG: sodium bicarbonate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Tobacco Dependence in Alcoholism Treatment (Nicotine Patch/Naltrexone)
Status: COMPLETED
Conditions: Alcoholism|Smoking
Interventions: DRUG: Naltrexone Tablet and Nicotine Patch|DRUG: Naltrexone Tablet and Placebo Patch|DRUG: Placebo Tablet and Nicotine Patch|DRUG: Placebo Tablet and Placebo Patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Azacitidine and Pembrolizumab in Treating Patients With Myelodysplastic Syndrome
Status: ACTIVE_NOT_RECRUITING
Conditions: High Risk Myelodysplastic Syndrome|IPSS Risk Category Intermediate-1|Myelodysplastic Syndrome
Interventions: DRUG: Azacitidine|BIOLOGICAL: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Safety and Pharmacokinetics of QAV680 Versus Placebo in Patients With Asthma
Status: TERMINATED
Conditions: Asthma
Interventions: DRUG: QAV680|DRUG: QAV680 Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Canadian Pegvisomant Compassionate Study In Acromegalic Patients
Status: COMPLETED
Conditions: Acromegaly
Interventions: DRUG: Pegvisomant treatment|PROCEDURE: Medical History, demographics|PROCEDURE: Sign and symptoms: questionnaire|PROCEDURE: Blood tests: IGF-1, AST/ALT/ALP/TBIL, GTT|PROCEDURE: MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Shoe Cushioning and Body Mass on Injury Risk in Running
Status: COMPLETED
Conditions: Running-Related Injury (First-time)
Interventions: OTHER: Hard cushioned running shoes|OTHER: Soft cushioned running shoes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: DMT310-001 Topical in the Treatment of Acne Vulgaris
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: DMT310|DRUG: Hydrogen Peroxide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Maintenance Treatment Versus Observation After Induction in Advanced Colorectal Carcinoma
Status: UNKNOWN
Conditions: Colorectal Cancer Metastatic
Interventions: DRUG: capecitabine + bevacizumab|OTHER: observation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Polyp Detection Rate After Single Oral Dose of Methylene Blue MMX Modified Release Tablets Administered to Subjects Undergoing Outpatients Colonoscopy
Status: COMPLETED
Conditions: Polyp and Adenoma Detection During Colonoscopy
Interventions: DEVICE: oral tablet dye for detection of polyps during colonoscopy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The AXIS Study: the Efficacy of Acetazolamide for the Treatment of Cystoid Fluid Collections in Retinoschisis
Status: RECRUITING
Conditions: Retinoschisis
Interventions: DRUG: Acetazolamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Low-dose Levetiracetam on Clinical Symptoms, Cognition and Hippocampal Hyperactivity in Schizophrenia
Status: RECRUITING
Conditions: Schizophrenia
Interventions: DRUG: Levetiracetam|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Study of ZSP1273 in Patients With Acute Uncomplicated Influenza A
Status: COMPLETED
Conditions: Influenza A
Interventions: DRUG: ZSP1273 200 mg|DRUG: Placebo|DRUG: ZSP1273-400 mg|DRUG: Placebo|DRUG: ZSP1273-600 mg|DRUG: Placebo|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare the Efficacy and Safety of Fluticasone Furoate (FF) 100 mcg Once Daily With Fluticasone Propionate (FP) 250 mcg Twice Daily (BD) and FP 100 mcg BD in Well-controlled Asthmatic Japanese Subjects
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Fluticasone Furoate/Vilanterol|DRUG: Fluticasone Furoate 100 mcg|DRUG: Fluticasone Propionate 250 mcg|DRUG: Fluticasone Propionate 100 mcg|DRUG: Fluticasone Furoate Placebo|DRUG: Fluticasone Propionate Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Alisertib and Pembrolizumab for the Treatment of Patients With Rb-deficient Head and Neck Squamous Cell Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Head and Neck Squamous Cell Carcinoma|Malignant Solid Neoplasm
Interventions: DRUG: Alisertib|BIOLOGICAL: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose Escalation Study of JNJ-54767414 (Daratumumab) in Chinese Participants With Relapsed or Refractory Multiple Myeloma Who Failed at Least 2 Prior Lines of Systemic Therapy
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Daratumumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Incidence of Palatal Fistula in Furlow Double-opposing Z-plasty vs. Two-flap Palatoplasty for Cleft Palate Repair
Status: UNKNOWN
Conditions: Fistula of Soft Palate (Disorder)
Interventions: PROCEDURE: Furlow double opposing z-plasty|PROCEDURE: Two flap palatoplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Systemic Light Exposure in Preventing Frailty in Older Patients With Prostate Cancer on Hormonal Therapy
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Carcinoma
Interventions: DEVICE: Actigraph|OTHER: Questionnaire Administration|PROCEDURE: Systematic Light Exposure|PROCEDURE: Systematic Light Exposure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Early Phase Study Comparing the Effectiveness of a Dairy Product With the Reference Treatment Aequasyal® on Dry Mouth Symptoms in Patients Suffering From Xerostomia Caused by Psychotropic Medications.
Status: UNKNOWN
Conditions: Xerostomia
Interventions: OTHER: Dairy product|DEVICE: Aequasyal mouth spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sirolimus, Tacrolimus, and Methotrexate in Preventing Acute Graft-Versus-Host Disease in Patients With Hematologic Cancer Who Are Undergoing Donor Stem Cell Transplantation
Status: COMPLETED
Conditions: Chronic Myeloproliferative Disorders|Graft Versus Host Disease|Leukemia|Lymphoma|Multiple Myeloma and Plasma Cell Neoplasm|Myelodysplastic Syndromes|Myelodysplastic/Myeloproliferative Diseases
Interventions: DRUG: methotrexate|DRUG: sirolimus|DRUG: tacrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phase III Placebo-controlled Study of V260 (RotaTeq™) in Japanese Healthy Infants (V260-029)(COMPLETED)
Status: COMPLETED
Conditions: Rotavirus|Gastroenteritis
Interventions: BIOLOGICAL: Rotavirus Vaccine, Live, Oral, Pentavalent (V260, RotaTeq™)|BIOLOGICAL: Comparator: Comparator: Placebo (unspecified)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Examining the Effect of Role-playing Exercise by Utilizing an Obesity Suit in a Simulation Scenario on Weight Bias and Empathy Levels Among Nutrition Sciences Students
Status: COMPLETED
Conditions: Obesity|Bias, Weight
Interventions: BEHAVIORAL: A role-playing exercise by utilizing an obesity suit in a simulation scenario
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of Tocilizumab and Methotrexate in Combination or as Monotherapy in Treatment-Naïve Patients With Early Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: methotrexate|DRUG: placebo MTX|DRUG: placebo TCZ|DRUG: tocilizumab [RoActemra/Actemra]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: 2 Weekly Intra-articular Hyaluronan Knee Injections, Given 1 wk. Apart, of HYMOVIS Combined With Physical Exercise Program (PEP) Compared to PEP Alone, in Relatively Young, Active Population of Subjects With Patellofemoral Osteoarthritis (PFOA) and/or Tibiofemoral Osteoarthritis (TFOA)
Status: COMPLETED
Conditions: Osteoarthritis, Knee|Knee Osteoarthritis|Patellofemoral Osteoarthritis
Interventions: DEVICE: HYMOVIS plus Physical Exercise Program (PEP)|OTHER: Physical Exercise Program (PEP) alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prevalence of Vertebral Fractures in Patients With Type 1 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1|Bone Fracture|Bone Health
Interventions: DIAGNOSTIC_TEST: Clinical tests|DIAGNOSTIC_TEST: Clinical tests|DIAGNOSTIC_TEST: Biochemical tests|DIAGNOSTIC_TEST: DXA scan|DIAGNOSTIC_TEST: AGE Reader
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Atezolizumab Plus CArboplatin Plus Nab-paclitaxel
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Breast Cancer|Triple Negative Breast Cancer|PD-L1 Gene Mutation
Interventions: COMBINATION_PRODUCT: Atezolizumab,Paclitaxel, Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Bobath Technique Versus Task Oriented Training on Gross Motor Function in Cerebral Palsy Children
Status: COMPLETED
Conditions: Cerebral Palsy
Interventions: OTHER: BOBATH technique|OTHER: Task training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rectal Gas Removal Through Small Catheter Placement Prior to MRI of the Prostate
Status: UNKNOWN
Conditions: Prostatic Neoplasms|Prostate Cancer
Interventions: PROCEDURE: small urinary catheter placement in the rectum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety and Feasibility Study of Rejuvenair™ for Treating Chronic Bronchitis Patients
Status: COMPLETED
Conditions: Bronchitis, Chronic|Cryotherapy Effect
Interventions: DEVICE: RejuvenAir
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Prospective Multicenter Sample Collection Study Using Non-invasive Methods to Investigate Mutation Burden in Non-lesional Facial Skin of Patients With a Hx of Skin Cancer
Status: NOT_YET_RECRUITING
Conditions: Melanoma and Other Malignant Neoplasms of Skin
Interventions: OTHER: Observational Study Only
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effectiveness of a Hydrophobic Dressing for Microorganisms' Colonization and Infection Control of Vascular Ulcers
Status: UNKNOWN
Conditions: Venous Leg Ulcer|Bacterial Infections|Chronic Ulcer of Skin of Lower Limb Nos
Interventions: COMBINATION_PRODUCT: CUTIMED|OTHER: AQUACEL silver
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Alfentanil Versus Sufentanil for Pain in Children During for Tracheal Suction
Status: COMPLETED
Conditions: Child Comfort|Morphine|Intensive Care Units|Pediatric
Interventions: DRUG: Alfentanil|DRUG: Sufentanil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Local Endometrial Injury on Pregnancy Outcomes During Ovulation Induction Cycles
Status: UNKNOWN
Conditions: Asymptomatic Diseases
Interventions: DEVICE: endometrial sampling|DRUG: clomiphene citrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Response and Toxicity of Hypo-fractionated Chemoradiotherapy in Cervix Cancer
Status: RECRUITING
Conditions: Cervix Uteri Cancer
Interventions: RADIATION: Hypofractionated EBRT|RADIATION: Standard EBRT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hysterectomy by Transabdominal Laparoscopy or NOTES
Status: COMPLETED
Conditions: Uterine Diseases
Interventions: PROCEDURE: vNOTES hysterectomy|PROCEDURE: LSC hysterectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: "Youth Aware of Mental Health" in Galicia
Status: ENROLLING_BY_INVITATION
Conditions: Suicide Awareness|Suicidal Ideation|Suicide, Attempted|Depressive Symptoms|Help-Seeking Behavior|Bullying|Cyberbullying
Interventions: BEHAVIORAL: Youth Aware of Mental Health in Galicia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Magnetic Resonance Temperature Imaging & Imaging-Guided Laser Induced Thermal Therapy for Treatment of Metastatic Brain Tumors
Status: TERMINATED
Conditions: Brain Tumor
Interventions: PROCEDURE: Visualase® Thermal Therapy System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Biofeedback Versus Vaginal Palpation to Teach a Voluntary Pelvic Floor Muscle Contraction
Status: RECRUITING
Conditions: Urinary Incontinence
Interventions: OTHER: a proprioception protocol associated with vaginal palpation and feedback|OTHER: a proprioception protocol associated with biofeedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prebiotic GOS and Lactoferrin With Iron Supplements
Status: COMPLETED
Conditions: Iron-deficiency
Interventions: DIETARY_SUPPLEMENT: Galacto-oligosaccharides|DIETARY_SUPPLEMENT: Bovine lactoferrin|DIETARY_SUPPLEMENT: Multiple micronutrient powders with 5 mg iron
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: How do Sleeping Pills Affect Pain in the Brain?
Status: TERMINATED
Conditions: Primary Insomnia
Interventions: DRUG: Eszopiclone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Differential Effects of Vasopressin and Oxytocin on Attention Control
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Vasopressin|DRUG: Oxytocin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Safety of Brodalumab Compared With Guselkumab in the Treatment of Plaque Psoriasis After Inadequate Response to Ustekinumab
Status: TERMINATED
Conditions: Plaque Psoriasis|Psoriasis Vulgaris|Psoriasis
Interventions: BIOLOGICAL: Brodalumab|OTHER: Placebo|BIOLOGICAL: Guselkumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cholinergic Neurotransmission in Mobility and Cognition in Parkinson Disease
Status: COMPLETED
Conditions: Parkinson Disease|Parkinson Disease Dementia
Interventions: DRUG: Rivastigmine transdermal patch
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Predicting Response to Capecitabine in Women With Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: capecitabine|OTHER: laboratory biomarker analysis|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: AEF0217 First-in-Human Phase I Study in 3 Parts (Single and Multiple Ascending Doses, and Food Effect) in Healthy Subjects.
Status: COMPLETED
Conditions: Safety, Tolerability, Pharmacokinetics of AEF0217
Interventions: DRUG: AEF0217|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Class iv Versus Class Iiib Laser Therapy on Median Sternotomy Healing After Coronary Artery Bybass Graft
Status: COMPLETED
Conditions: Wound|Wound Heal|Wound Infection
Interventions: DEVICE: laser therapy for wound management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of Best Supportive Care and Either Cisplatin or Paclitaxel to Treat Patients With Primary Ovarian Cancer, Primary Peritoneal Cancer or Fallopian Tube Cancer and Inoperable Malignant Bowel Obstruction
Status: TERMINATED
Conditions: Ovarian Cancer|Peritoneal Cancer|Fallopian Tube Cancer|Bowel Obstruction
Interventions: DRUG: Cisplatin|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multicenter Trial of Sprifermin (AS902330 [Recombinant Human Fibroblast Growth Factor-18]) or Placebo After Microfracture Surgery for Cartilage Injury of the Knee
Status: TERMINATED
Conditions: Cartilage Injury of Knee
Interventions: DRUG: Sprifermin (AS902330)|DRUG: Sprifermin (AS902330)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Low Intensity Training Combined With KAATSU on Muscle Vasodilatation and Arterial Stiffness in the Elderly Population
Status: COMPLETED
Conditions: Frail Elderly Syndrome
Interventions: PROCEDURE: 1RM Test|PROCEDURE: Speed gait test|DEVICE: Venous occlusion plethysmography protocol|DEVICE: Measurement of Arterial Stiffness - Pulse Wave Analysis and Velocity|DEVICE: Isometric handgrip exercise protocol|DEVICE: Vasodilatory capacity|DEVICE: Basal blood flow and vasodilatory capacity - Flow mediated dilation (FMD)|DIAGNOSTIC_TEST: Quality of Life EuroQol-5 Domain|OTHER: Anthropometric Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Phase I, Multicenter, Clinical Trial to Evaluate the Safety and Immunogenicity of Vaccinia-Derived MN HIV-1 Recombinant Envelope Glycoprotein (rgp160) of Human Immunodeficiency Virus at Two Different Vaccination Schedules
Status: COMPLETED
Conditions: HIV Infections
Interventions: BIOLOGICAL: gp160 Vaccine (Immuno-AG)
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: PREVENTION
Clinical trial: Effects of Degludec/Liraglutide on Time in Range, Inflammation and Endothelial Function vs Insulin Basal Bolus in Diabetic Inpatients
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Insulin Degludec / Liraglutide Injectable Product|DRUG: Insulin Glargine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: PhI Pilot Study Pafolacianine Injec for Intraoperative Imag Gastrointestinal Can Peritoneal Carcinomatosis
Status: NOT_YET_RECRUITING
Conditions: Gastrointestinal Cancer|Peritoneal Carcinomatosis
Interventions: DRUG: Pafolacianine (CYTALUX) with intraoperative fluorescent near-infrared (NIR) imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Auricular Acupressure as a Non-Opioid Adjuvant in Opioid Tolerant Patients
Status: COMPLETED
Conditions: Opioid Use Disorder
Interventions: DEVICE: Auricular Acupressure with Vaccaria 600t ear seeds
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Assessment of Anterior Teeth Restored With Ultra-translucent Multilayer Zirconia vs Lithium Disilicate Laminate Veneers
Status: UNKNOWN
Conditions: Retention, Color Match, Marginal Adaptation and Restoration Integrity
Interventions: PROCEDURE: Ultra-translucent multilayer zirconia|PROCEDURE: Lithium disilicate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acupuncture in Treating Women With Stage I, Stage II, or Stage III Breast Cancer With Aromatase Inhibitor-Related Joint Pain
Status: COMPLETED
Conditions: Breast Cancer|Recurrent Breast Cancer|Stage I Breast Cancer|Stage II Breast Cancer|Stage IIIA Breast Cancer|Stage IIIB Breast Cancer|Stage IIIC Breast Cancer
Interventions: PROCEDURE: acupuncture therapy|PROCEDURE: sham intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Myrbetriq™ (Mirabegron) to Reduce Pain and Discomfort Following Ureteral Stent Placement
Status: TERMINATED
Conditions: Urinary Bladder, Overactive|Pain|Lower Urinary Tract Symptoms
Interventions: DRUG: Mirabegron|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of a New Device for Making Neochordae in Mitral Valve Repair
Status: UNKNOWN
Conditions: Mitral Valve Repair
Interventions: DEVICE: Artificial Chordae
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Apatinib Combined With SHR-1210 Injection in the Treatment of Patients With Removable IB-IIIA NSCLC
Status: UNKNOWN
Conditions: Lung Diseases|Neoplasms|Respiratory Tract Diseases|Thoracic Neoplasms|Non-small-cell Lung Cancer
Interventions: DRUG: Apatinib|DRUG: SHR-1210
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: One Month Dual Antiretroviral Prophylaxis to Prevent Resistance Mutations in Mothers Exposed to Single Dose Nevirapine
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Zidovudine (ZDV)|DRUG: Didanosine (ddI)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of Capecitabine [Xeloda] in Combination With Trastuzumab [Herceptin] and Oxaliplatine in Patients With Resectable Gastric Cancer
Status: COMPLETED
Conditions: Gastric Cancer
Interventions: DRUG: Capecitabine [Xeloda]|DRUG: Oxaliplatin|DRUG: Trastuzumab [Herceptin]
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pragmatic Investigation of optimaL Oxygen Targets Trial
Status: COMPLETED
Conditions: Respiratory Failure
Interventions: OTHER: Lower SpO2 Target|OTHER: Intermediate SpO2 Target|OTHER: Higher SpO2 Target
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clostridium Difficile Vaccine Safety, Tolerability, and Immunogenicity Study in Japanese Adults
Status: COMPLETED
Conditions: Clostridium Difficile Associated Disease
Interventions: BIOLOGICAL: Clostridium difficile Vaccine|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Efficacy and Safety of Sofosbuvir/Velpatasvir Fixed-Dose Combination in Participants With Chronic Hepatitis C Virus Infection
Status: COMPLETED
Conditions: Hepatitis C Virus Infection
Interventions: DRUG: SOF/VEL
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Daptomycin Versus Vancomycin or Teicoplanin for Treatment of Complicated Skin and Soft Tissue Infections
Status: TERMINATED
Conditions: Skin Diseases, Infectious|Soft Tissue Infections
Interventions: DRUG: Daptomycin|DRUG: Vancomycin|DRUG: Teicoplanin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Laryngeal Mask Airway With Video-stylet
Status: UNKNOWN
Conditions: Anesthesia; Functional
Interventions: DEVICE: Laryngeal mask insertion with videostylet guided technique|DEVICE: Laryngeal mask insertion with standard blind technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Gemcitabine Hydrochloride, Cisplatin, and Nab-Paclitaxel in Treating Patients With Advanced or Metastatic Biliary Cancers
Status: COMPLETED
Conditions: Stage III Intrahepatic Cholangiocarcinoma AJCC v7|Stage IIIA Gallbladder Cancer AJCC v7|Stage IIIB Gallbladder Cancer AJCC v7|Stage IVA Gallbladder Cancer AJCC v7|Stage IVA Intrahepatic Cholangiocarcinoma AJCC v7|Stage IVB Gallbladder Cancer AJCC v7|Stage IVB Intrahepatic Cholangiocarcinoma AJCC v7|Unresectable Extrahepatic Bile Duct Carcinoma|Unresectable Gallbladder Carcinoma
Interventions: DRUG: Cisplatin|DRUG: Gemcitabine Hydrochloride|OTHER: Laboratory Biomarker Analysis|DRUG: Nab-paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Onset of Action of Advair Hydrofluoroalkane (HFA) 115/21 in Comparison to Symbicort Pressurised Metered-Dose Inhalers (pMDI) 160/4.5 Measured by Impulse Oscillometry (IOS)
Status: UNKNOWN
Conditions: Asthma
Interventions: DRUG: Advair HFA MDI 115/21|DRUG: Symbicort 160/4.5 pMDI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Side Effects and Relative Activity of Two Chemotherapy Regimens in the Treatment Soft Tissue Sarcoma
Status: COMPLETED
Conditions: Sarcoma, Soft Tissue
Interventions: DRUG: ifosfamide and doxorubicin vs gemcitabine and docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Determine the Absolute Bioavailability and the Absorption, Metabolism, and Elimination Properties of Carbon-14 (14C)E7386 in Healthy Male Participants
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: E7386 Tablet|DRUG: (14C)E7386 Capsule|DRUG: (14C)E7386
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Phase 3 Study of Difelikefalin in Haemodialysis Chinese Adult Subjects With Moderate-to-Severe Pruritus
Status: ACTIVE_NOT_RECRUITING
Conditions: Uremic Pruritus
Interventions: DRUG: Difelikefalin Injection|DRUG: Placebo Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Patient Satisfaction With and Acceptance of Their Totally-implanted Central Venous Catheter
Status: TERMINATED
Conditions: Malignant Mast Cell Tumors|Solid Organ Sites
Interventions: OTHER: QUALITY OF LIFE QUESTIONNAIRE
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Effect of DPP4 Inhibition on Vasoconstriction
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Sitagliptin|DRUG: Placebo|DRUG: Neuropeptide Y|DRUG: Enalaprilat|DRUG: Valsartan 160mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE