pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Randomized Phase III Trial Comparing Sequential Administration of FE75C Followed by Docetaxel Versus Paclitaxel as Adjuvant Chemotherapy in Axillary Lymph Node (+) Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Docetaxel|DRUG: Paclitaxel|DRUG: Epirubicin|DRUG: Cyclophosphamide|DRUG: 5-fluoruracil|DRUG: Granulocyte-colony stimulating growth factor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Proximal Tibial Open Wedge Osteotomy. A Clinical Prospective, Randomized RSA-trial.
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: PROCEDURE: bonesubstitution (Calcibon, Iliac Crest Bonegraft, control)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasound Guided Serratus Anterior Versus Erector Spinae Block in Pain Alleviation in Acute Herpes Zoster
Status: NOT_YET_RECRUITING
Conditions: Acute Herpes Zoster Neuropathy
Interventions: PROCEDURE: ultrasound guided erector spine block|PROCEDURE: Serratus anterior block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective Evaluation of the Effectiveness of the Femtosecond Laser-assisted Refractive Astigmatic Keratotomy.
Status: COMPLETED
Conditions: Astigmatism
Interventions: DEVICE: Laser-assisted Astigmatic keratotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effects of ASA404 Alone or in Combination With Taxane-based Chemotherapies on the Pharmacokinetics of Drugs in Patients With Advanced Solid Tumor Malignancies
Status: TERMINATED
Conditions: Solid Tumor Malignancies
Interventions: DRUG: ASA404, DMXAA, DXAA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Auricular Acupressure on Improving Pain and Heart Variability in Patients After Cervical Spine Surgery
Status: COMPLETED
Conditions: Auricular Acupressure|Cervical Spine Surgery
Interventions: PROCEDURE: auricular acupressure|OTHER: standard ward care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Phase III RCT of Radiotherapy Plus Toripalimab Versus Sorafenib in Advanced Hepatocellular Carcinoma With PVTT
Status: RECRUITING
Conditions: Radiotherapy|Toripalimab|Sorafenib|Advanced Hepatocellular Carcinoma
Interventions: OTHER: Radiotherapy plus Toripalimab|DRUG: Sorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improvement of Support to Caregivers of Patients in Specialized Palliative Care at Home
Status: COMPLETED
Conditions: Palliative Care
Interventions: BEHAVIORAL: The Carer Support Needs Assessment Tool (CSNAT) intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: VIDAZA-DLI Pre-emptive Azacitidine and Donor Lymphocyte Infusions Following Allogeneic Hematopoietic Stem Cell Transplantation for High Risk Acute Myeloid Leukemia and Myelodysplastic Syndrome
Status: COMPLETED
Conditions: Acute Myeloid Leukemia|Myelodysplastic Syndrome
Interventions: DRUG: Azacitidine|OTHER: DLI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness Assessment of Riluzole in the Prevention of Oxaliplatin-induced Peripheral Neuropathy.
Status: ACTIVE_NOT_RECRUITING
Conditions: Oxaliplatin-induced Peripheral Neuropathy
Interventions: DRUG: Riluzole|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pharmacokinetics of Two Different High-dose Regimens of Intravenous Vitamin C in Critically Ill Patients
Status: COMPLETED
Conditions: Multiple Organ Failure|Sepsis|Systemic Inflammatory Response Syndrome|Trauma
Interventions: DRUG: Ascorbic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Mirtazapine and Folic Acid for Schizophrenia:
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: mirtazapine|DRUG: folic acid placebo|DRUG: mirtazapine placebo|DRUG: folic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Different Dosages of Paraxanthine, the Major Caffeine Metabolite, on Energy and Focus
Status: COMPLETED
Conditions: Energy|Focus|Caffeine Withdrawal
Interventions: OTHER: Paraxanthine 200 mg|OTHER: Paraxanthine 300 mg|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: The Hong Kong Diabetes Biobank
Status: RECRUITING
Conditions: Diabetes Mellitus|Type 2 Diabetes|Type 1 Diabetes|Diabetic Nephropathies|Diabetic Kidney Disease|Diabetic Angiopathies|Cardiovascular Diseases|Coronary Heart Disease|Diabetic Retinopathy|Stroke|Diabetes
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of SubQ Dara With Dose-Attenuated Bortezomib, Lenalidomide, Dexamethasone in Elderly NDMM
Status: RECRUITING
Conditions: Newly Diagnosed Multiple Myeloma
Interventions: DRUG: Daratumumab|DRUG: Bortezomib|DRUG: Lenalidomide|DRUG: Dexamethasone|DRUG: Ixazomib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A 1-year Multi-center, Prospective, Cohort Study in Patients With Chronic Obstructive Pulmonary Disease Treated With Long-acting Bronchodilator
Status: COMPLETED
Conditions: COPD
Interventions: DRUG: LABA based treatment: indacaterol|DRUG: LAMA based treatment: tiotropium|DRUG: LABA/ICS based treatment: salmeterol/fluticasone|DRUG: LABA/ICS based treatment: budesonide/formoterol|DRUG: theophylline based treatment|DRUG: Other treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intrabucally Administered Electromagnetic Fields Versus Placebo as Third-line Therapy For Patients With Advanced Hepatocellular Carcinoma
Status: WITHDRAWN
Conditions: Hepatocellular Carcinoma
Interventions: DEVICE: TheraBionic Device|DEVICE: Placebo Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The ECLA PHRI COLCOVID Trial. Effects of Colchicine on Moderate/High-risk Hospitalized COVID-19 Patients.
Status: COMPLETED
Conditions: COVID-19
Interventions: DRUG: Colchicine|OTHER: Local standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability Study in Patients With Mild to Moderate Alzheimer's Disease (AD)
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: BIOLOGICAL: CAD106|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Liposomal Doxorubicin, Trastuzumab, and Docetaxel in HER2 Positive Metastatic Breast Cancer
Status: TERMINATED
Conditions: Breast Cancer|Neoplasm Metastasis
Interventions: DRUG: Non pegylated liposomal doxorubicin, trastuzumab, docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testopel ® vs. Generic Testosterone Pellets.
Status: COMPLETED
Conditions: Hypogonadism
Interventions: DRUG: Testopel 75mg Drug Implant|DRUG: Testopel 100mg Drug Implant|DRUG: Testopel 200mg Drug Implant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Anticoagulation Prolongation vs. no Anticoagulation in STEMI Patients After Primary PCI
Status: COMPLETED
Conditions: STEMI - ST Elevation Myocardial Infarction
Interventions: DRUG: Bivalirudin|DRUG: Enoxaparin|DRUG: Unfractionated heparin|DRUG: Bivalirudin placebo|DRUG: Enoxaparin placebo syringe|DRUG: Unfractionated heparin placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SIOPEN BIOPORTAL, An International Registry Linked to a Virtual Biobank for Patients With Peripheral Neuroblastic Tumours
Status: RECRUITING
Conditions: Neuroblastoma|Ganglioneuroblastoma|Ganglioneuroma
Interventions: OTHER: No Intervention NA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Using "Store and Forward" Tele-health as an Adjunct to Traditional Outpatient or Home Health Physical Therapy
Status: COMPLETED
Conditions: Chronic Disease
Interventions: OTHER: Adjunct Therapy|OTHER: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Robot-assisted Thoracic Approach Versus Open Transthoracic Esophagectomy .
Status: RECRUITING
Conditions: Esophageal Cancer|Esophageal Carcinoma|Postoperative Complications
Interventions: PROCEDURE: Esophagectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 1A/1B Study of PSA/IL-2/GM-CSF Vaccine for Recurrent Prostate Cancer in Hormone Naive and Hormone Independent Patients
Status: UNKNOWN
Conditions: Prostate Cancer
Interventions: BIOLOGICAL: PSA/IL-2/GM-CSF
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use Ear Acupuncture as Treatment for Low Back Pain During Pregnancy
Status: COMPLETED
Conditions: Pregnancy Related Low Back Pain
Interventions: OTHER: acupuncture|OTHER: Sham acupuncture|OTHER: standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Effect of Food on the Pharmacokinetics of Single Dose RO5185426 And the Safety And Efficacy of Continuous Administration in Patients With BRAF V600E Mutation-Positive Metastatic Melanoma
Status: COMPLETED
Conditions: Malignant Melanoma
Interventions: DRUG: RO5185426|DRUG: RO5185426|DRUG: RO5185426
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Biofeedback Training in Schoolchildren With an Attention-Deficit/Hyperactivity Disorder (ADHD)
Status: UNKNOWN
Conditions: Attention-deficit Hyperactivity Disorder of Childhood or Adolescence Nos
Interventions: BEHAVIORAL: EMG-based biofeedback training|BEHAVIORAL: NIRS-based neurofeedback training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Chemo (Gemcitabine and Cisplatin) With Radical Cystectomy or Radiotherapy in Patients With Bladder Cancer
Status: COMPLETED
Conditions: Bladder Cancer
Interventions: DRUG: gemcitabine|DRUG: cisplatin|PROCEDURE: radical cystectomy|PROCEDURE: radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Palonosetron Versus Ramosetron for the Prevention of Postoperative Nausea and Vomiting
Status: COMPLETED
Conditions: Postoperative Nausea and Vomiting
Interventions: DRUG: palonosetron|DRUG: Ramosetron
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Co-administration of ABT-493 and ABT-530 With and Without Ribavirin in Subjects With HCV Genotype 1, 4, 5, and 6 Infection
Status: COMPLETED
Conditions: Chronic Hepatitis C|Hepatitis C Virus|HCV
Interventions: DRUG: ABT-493|DRUG: ABT-530
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Piperacillin-tazobactam as Empirical Antimicrobial Therapy for VAP Among ESBL-E Carriers.
Status: COMPLETED
Conditions: Enterobacteriaceae Infections
Interventions: DRUG: Piperacillin-tazobactam
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect and Safety of Low-level Laser Therapy in Acute Decompensated Heart Failure Patients.
Status: COMPLETED
Conditions: Heart Failure|Acupuncture
Interventions: PROCEDURE: Acupuncture|DEVICE: Low-level laser therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cardioprotective Effects of Omega-3 Fatty Acids Supplementation in Healthy Older Subjects Exposed to Air Pollution Particles
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Fish oil|DIETARY_SUPPLEMENT: Olive oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of Dual-energy (DE) Contrast-enhanced (CE) Digital Mammography
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DEVICE: Dual-Energy Contrast-Enhanced (DECE) mammography|DEVICE: digital mammography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Efficacy of Hand Narrow-Band Ultraviolet B (NBUVB) Versus Excilite Treatment in Vitiligo After Minigrafting on the Dorsal Hands
Status: COMPLETED
Conditions: Vitiligo
Interventions: DEVICE: NBUVB|DEVICE: Monochromacitc Excimer light
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating The Effects Of Cimetidine On The Elimination Of PD 0332334 From The Body
Status: TERMINATED
Conditions: Generalized Anxiety Disorder
Interventions: DRUG: PD 0332334|DRUG: PD 0332334|DRUG: cimetidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Low Dose Dexamethasone to Local Anesthetic in Caudal Analgesia on Healing Process After Orthopaedic Surgery
Status: NOT_YET_RECRUITING
Conditions: Anesthesia
Interventions: PROCEDURE: Intrathecal dexamethason
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ertugliflozin Type 2 Diabetes Mellitus (T2DM) Pediatric Study (MK-8835/PF-04971729) (MK-8835-059)
Status: ACTIVE_NOT_RECRUITING
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Ertugliflozin 5 mg|DRUG: Ertugliflozin 15 mg|DRUG: Placebo to ertugliflozin 15 mg|DRUG: Placebo to ertugliflozin 5 mg|BIOLOGICAL: Insulin|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Perioperative or Adjuvant mFOLFIRINOX for Resectable Pancreatic Cancer
Status: RECRUITING
Conditions: Pancreatic Cancer|Pancreatic Ductal Adenocarcinoma|Resectable Pancreatic Adenocarcinoma
Interventions: DRUG: Leucovorin Calcium|DRUG: Fluorouracil|DRUG: Irinotecan Hydrochloride|DRUG: Oxaliplatin|PROCEDURE: Resection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase III Trial of Dantonic® (T89) Capsule to Prevent and Treat Stable Angina
Status: COMPLETED
Conditions: Angina Pectoris
Interventions: DRUG: T89 high dose|DRUG: T89 Low dose|DRUG: Sanqi+Bingpian|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 2b, Randomized, Double-blind Study of Redasemtide (S-005151) in Adult Participants With Acute Ischemic Stroke
Status: RECRUITING
Conditions: Acute Ischemic Stroke
Interventions: BIOLOGICAL: Redasemtide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Efficacy and Safety of DWP14012 in Patients With Non Erosive Reflux Disease
Status: UNKNOWN
Conditions: Non-Erosive Gastroesophageal Reflux Disease
Interventions: DRUG: DWP14012 A mg|DRUG: DWP14012 B mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of TJ271 Injection Combined With Pembrolizumab in the Treatment of Advanced Solid Tumors
Status: WITHDRAWN
Conditions: First-line Non-small-cell Lung Cancer|First-line Urothelial Carcinoma|Second-line Urothelial Carcinoma|Second-line Melanoma
Interventions: DRUG: TJ271 Injection in Combination with Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hormone Therapy With or Without Combination Chemotherapy in Treating Women Who Have Undergone Surgery for Node-Negative Breast Cancer (The TAILORx Trial)
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Adenocarcinoma|Hormone Receptor Positive|Stage IA Breast Cancer AJCC v7|Stage IB Breast Cancer AJCC v7|Stage IIA Breast Cancer AJCC v6 and v7|Stage IIB Breast Cancer AJCC v6 and v7|Stage IIIB Breast Cancer AJCC v7
Interventions: DRUG: Anastrozole|DRUG: Exemestane|OTHER: Laboratory Biomarker Analysis|DRUG: Letrozole|OTHER: Quality-of-Life Assessment|RADIATION: Radiation Therapy|DRUG: Tamoxifen Citrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Long Term Post-Marketing Study on the EffIcacy and Safety of Osmotic Release Oral System (OROS) Methylphenidate on the Cognitive Functions of Attention Deficit Hyperactivity Disorder (ADHD) Participants
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder (ADHD)
Interventions: DRUG: Osmotic Release Oral System Methylphenidate Hydrochloride (OROS-MPH)|OTHER: No intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the PK of NRL972 Following Pre- and co-Administration of Ursodeoxycholic Acid and Cloxacillin
Status: COMPLETED
Conditions: Hepatic Cirrhosis
Interventions: DRUG: NRL972|DRUG: NRL972|DRUG: NRL972
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Single Ascending Dose Study of Safety and Tolerability of Sarilumab and Methotrexate in Japanese Patients With Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: sarilumab SAR153191 (REGN88)|DRUG: placebo|DRUG: methotrexate|DRUG: folic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Buparlisib in Patients With Relapsed and Refractory Chronic Lymphocytic Leukemia
Status: COMPLETED
Conditions: Chronic Lymphocytic Leukemia
Interventions: DRUG: Buparlisib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of HTD1801 in Adolescents With Primary Sclerosing Cholangitis (PSC)
Status: WITHDRAWN
Conditions: Primary Sclerosing Cholangitis|Cholangitis|Cholangitis, Sclerosing|Bile Duct Diseases|Biliary Tract Diseases|Digestive System Diseases|Adolescent
Interventions: DRUG: HTD1801|DRUG: Ursodeoxycholic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Effects of GSK573719/VI Combination and GSK573719 Monotherapy in Subjects With Moderate Hepatic Impairment and Matched Healthy Volunteers
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Inhaled GSK573719/vilanterol|DRUG: Inhaled GSK573719
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Safety of L-asparaginase Encapsulated in RBC Combined With Gemcitabine or FOLFOX in 2nd Line for Progressive Metastatic Pancreatic Carcinoma
Status: COMPLETED
Conditions: Pancreatic Adenocarcinoma Metastatic
Interventions: DRUG: ERY001|DRUG: Gemcitabine|DRUG: 5-fluoro-uracil/oxaliplatin/leucovorin (folfox)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of MEnstruation on Glycemic Response and Exercise In Females With Type 1 Diabetes
Status: RECRUITING
Conditions: Type 1 Diabetes|Hypoglycemia|Hyperglycaemia Due to Type 1 Diabetes Mellitus|Menstruation Disturbances
Interventions: OTHER: Personalized modifications to treatment to address menstrual cycle effects on glycemia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Prospective Controlled Study on Treatment of Giant Cavernous Hemangiomas of the Liver
Status: COMPLETED
Conditions: Laparoscopic Hepatectomy|Radio-frequency Ablation|Giant Cavernous Hemangiomas|Liver
Interventions: PROCEDURE: RFA|PROCEDURE: hepatectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Frequency of Central Sensitization in Patients With Chronic Musculoskeletal Pain
Status: ACTIVE_NOT_RECRUITING
Conditions: Central Sensitisation|Chronic Musculoskeletal Disease|Chronic Pain
Interventions: DIAGNOSTIC_TEST: Central sensitization inventory|OTHER: Short form-36|OTHER: Istanbul Low Back Pain Disability Index|OTHER: Disabilities of the Arm, Shoulder and Hand (DASH)|OTHER: Neck Pain and Disability scale|OTHER: Knee Injury and Osteoarthritis Outcome Score|OTHER: Western Ontario and McMaster Universities Arthritis Index|OTHER: Visual analogue scale
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Hyperbaric Oxygen Therapy in Distal Radius Fractures: Can it Shorten Recovery Time and Increase Fracture Healing?
Status: SUSPENDED
Conditions: Hyperbaric Oxygen Therapy|Recovery Time|Contrast Media|Sonography
Interventions: PROCEDURE: Hyperbaric Oxygen Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospectively Collected Pleural Biopsies for Validation of Malignant Pleural Mesothelioma Prognostic Biomarkers
Status: RECRUITING
Conditions: Mesothelioma
Interventions: OTHER: MPT Test|OTHER: CLDN15/VIM Test
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Intraoperative Infusion of Dexmedetomidine for Prevention of Postoperative Delirium in Elderly Patients
Status: UNKNOWN
Conditions: Dexmedetomidine|Postoperative Delirium
Interventions: DRUG: Dexmedetomidine|DRUG: 0.9% saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Effect of Tacrolimus and Corticosteroid Combination Therapy in Patients With Minimal Change Nephrotic Syndrome
Status: COMPLETED
Conditions: MCNS|Minimal Change Nephrotic Syndrome (MCNS)
Interventions: DRUG: Tacrolimus|DRUG: Prednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dexamethasone With TAP Block Increasing the Duration of the Peripheral Nerve Block in Caesarian Section
Status: UNKNOWN
Conditions: Pain
Interventions: DRUG: Dexamethasone in addition to TAP block in dose of 4 mg|DRUG: Dexamethasone in combination with TAP block in dose of 8 mg|DRUG: Dexamethasone intravenous 4mg+ TAP block|DRUG: Dexamethasone intravenous in addition to TAP block in dose of 8 mg|OTHER: control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SMaRT Blood: Single-unit Versus Multiple-unit Packed Red Blood Cell Transfusion in Non-acute Postpartum Anemia
Status: COMPLETED
Conditions: Postpartum Anemia Nos
Interventions: BIOLOGICAL: Blood Transfusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anesthesia Induction With Intravenous Bolus or Continuous Infusion of Remimazolam
Status: COMPLETED
Conditions: Adult|Anesthesia, General
Interventions: DRUG: Bolus injection of remimazolam|DRUG: Infusion of remimazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Safety of Abraxane Combined With Epirubicin as Neoadjuvant Chemotherapy in Breast Cancer
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: DRUG: Abraxane|DRUG: Epirubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of an Amino Acid and Chromium-picolinate Containing Drink on Glucose Metabolism on Healthy Subjects
Status: COMPLETED
Conditions: Diabetes
Interventions: DIETARY_SUPPLEMENT: Amino Acids and chromium-picolinate containing drink|DIETARY_SUPPLEMENT: Placebo drink
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study on the Pharmacokinetics and Safety of Valcyte (Valganciclovir) in Pediatric Heart Transplant Recipients Less Than 4 Months of Age
Status: COMPLETED
Conditions: Cytomegalovirus Infections, Heart Transplantation
Interventions: DRUG: valganciclovir [Valcyte]
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Interventions for Safe Patient Handling and Movement in the Healthcare Sector
Status: ACTIVE_NOT_RECRUITING
Conditions: Occupational Health
Interventions: OTHER: Arm A) Multifactorial intervention strategy|OTHER: Arm B) Single intervention strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Long-Term Study To Evaluate Safety And Efficacy Of Pregabalin For Pain Associated With Diabetic Peripheral Neuropathy
Status: COMPLETED
Conditions: Diabetic Neuropathy, Painful
Interventions: DRUG: pregabalin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of BIIB022 in Combination With Paclitaxel and Carboplatin in Subjects With Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: BIIB022 With Paclitaxel and Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Extension Study to Evaluate the Long-term Outcomes of Subjects in Study 20090
Status: ACTIVE_NOT_RECRUITING
Conditions: Retinopathy of Prematurity (ROP)
Interventions: DRUG: Eylea (Aflibercept, BAY86-5321)|PROCEDURE: Laser photocoagulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Efficacy and Safety of Aspirin Therapy With CABG
Status: UNKNOWN
Conditions: Coronary Heart Disease
Interventions: DRUG: acetylsalicylic acid started for 24 hours before surgery|DRUG: acetylsalicylic acid stayed for 5 days before surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: IORT Followed by CCRT or SBRT for Locally Advanced Pancreatic Cancer
Status: UNKNOWN
Conditions: Pancreatic Cancer
Interventions: RADIATION: Concurrent chemoradiotherapy(CCRT)|RADIATION: Stereotactic Radiotherapy(SBRT)|DRUG: S-1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Split Thickness Donor Site Healing With MIST Study
Status: COMPLETED
Conditions: Burns|Trauma|Venous Ulcers
Interventions: DEVICE: MIST Therapy|OTHER: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Shear Wave Elastography in Gestational Diabetes Mellitus
Status: COMPLETED
Conditions: Gestational Diabetes Mellitus in Pregnancy
Interventions: OTHER: SWE is a novel noninvasive dynamic ultrasound technique which refers to measurement for quantitative analysis of tissue elasticity
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Evaluation of Retina in Patients With Glaucoma Using Topical Prostaglandins Undergoing Trabeculectomy Surgery
Status: COMPLETED
Conditions: Glaucoma
Interventions: PROCEDURE: Trabeculectomy surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study Investigating the Effect of EDP1815 in the Treatment of Mild, Moderate and Severe Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: EDP1815|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Associative Memory in Adults With an Autism Spectrum Disorder
Status: UNKNOWN
Conditions: Autistic Disorder
Interventions: DEVICE: Electroencephalography|BEHAVIORAL: Neuropsychological assesments
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Phase I Study to Investigate the Safety, Tolerability and PK of HLX60 (Anti-GARP Monoclonal Antibody) in Subjects With Solid Tumors or Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Solid Tumor and Lymphoma
Interventions: DRUG: HLX60
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Short Life Agents in Balanced Anesthesia on Obstructive Sleep Apnea Syndrome
Status: COMPLETED
Conditions: Sleep Apnea Syndromes|Sleep Apnea, Obstructive
Interventions: DRUG: Fentanyl and sevoflurane|DRUG: Remifentanil and desflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of HB-202/HB-201 in People With Human Papilloma Virus 16-Positive Head and Neck Squamous Cell Cancer (HPV 16+ HNSCC)
Status: RECRUITING
Conditions: HPV16+ Squamous Cell Carcinoma
Interventions: DRUG: HB-200|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of a Stainless Steel Suture MGH Flexor Tendon Repair Coupled With Early Aggressive Range of Motion Rehabilitation: a Randomized Controlled Trial
Status: UNKNOWN
Conditions: Zone 2 Flexor Tendon Lacerations of the Hand
Interventions: PROCEDURE: Stainless steel suture|PROCEDURE: Polypropylene suture|BEHAVIORAL: Aggressive early active range of motion rehabilitation|BEHAVIORAL: Early active range of motion rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lenalidomide in Treating Young Patients With Recurrent, Progressive, or Refractory CNS Tumors
Status: COMPLETED
Conditions: Childhood Atypical Teratoid/Rhabdoid Tumor|Childhood Central Nervous System Germ Cell Tumor|Childhood Choroid Plexus Tumor|Childhood Craniopharyngioma|Childhood Ependymoblastoma|Childhood Grade I Meningioma|Childhood Grade II Meningioma|Childhood Grade III Meningioma|Childhood High-grade Cerebellar Astrocytoma|Childhood High-grade Cerebral Astrocytoma|Childhood Infratentorial Ependymoma|Childhood Low-grade Cerebellar Astrocytoma|Childhood Low-grade Cerebral Astrocytoma|Childhood Medulloepithelioma|Childhood Mixed Glioma|Childhood Oligodendroglioma|Childhood Supratentorial Ependymoma|Recurrent Childhood Brain Tumor|Recurrent Childhood Cerebellar Astrocytoma|Recurrent Childhood Cerebral Astrocytoma|Recurrent Childhood Ependymoma|Recurrent Childhood Medulloblastoma|Recurrent Childhood Pineoblastoma|Recurrent Childhood Subependymal Giant Cell Astrocytoma|Recurrent Childhood Supratentorial Primitive Neuroectodermal Tumor|Recurrent Childhood Visual Pathway and Hypothalamic Glioma
Interventions: DRUG: lenalidomide|PROCEDURE: perfusion-weighted magnetic resonance imaging|PROCEDURE: diffusion-weighted magnetic resonance imaging|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence of Losartan and Hydrochlorothiazide (HCTZ) Combination Tablet and Coadministration of Its Components (0954A-306)
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: losartan potassium (+) hydrochlorothiazide (HCTZ)|DRUG: losartan potassium|DRUG: hydrochlorothiazide (HCTZ)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Group GDS and Individual GDS for Treatment of Low Back Pain in Primary Care
Status: COMPLETED
Conditions: Subacute Nonspecific Low Back Pain|Chronic Nonspecific Low Back Pain
Interventions: BEHAVIORAL: Education on active management|OTHER: Group GDS physiotherapy|OTHER: Individual GDS physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Dupilumab and Immune Responses in Adults With Atopic Dermatitis (AD)
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: Dupilumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Drug - Drug Interaction Study of Quinine Sulfate and Ciprofloxacin
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Quinine Sulfate Capsules 324 mg|DRUG: Ciprofloxacin 500 mg|DRUG: Quinine Sulfate Capsules 324 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Cardiac and Vascular Responses to Creatine Supplementation in Elderly Men
Status: RECRUITING
Conditions: Cardiac Function and Hemodynamics
Interventions: DIETARY_SUPPLEMENT: Creatine Monohydrate|DIETARY_SUPPLEMENT: Maltodextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized Controlled Trial Evaluating Sildenafil Citrate in Relieving Ureteral Stent Related Symptoms
Status: COMPLETED
Conditions: Quality of Life
Interventions: DRUG: Sildenafil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pulsed Abraxane and Radiotherapy for Improving and Maintaining Ambulation After Cancer-Related Cord Compression
Status: TERMINATED
Conditions: Cord Compression
Interventions: RADIATION: Radiation therapy|DRUG: nab-Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Carotenoids for Collision Athletes
Status: NOT_YET_RECRUITING
Conditions: Head Injury|Carotenoids
Interventions: DRUG: Vision Edge Pro|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Circulating Tumour DNA Guided Adaptive BRAF and MEK Inhibitor Therapy
Status: NOT_YET_RECRUITING
Conditions: Melanoma
Interventions: DRUG: Adaptive Therapy|DRUG: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Intracranially Implanted Carmustine to Treat Newly Diagnosed Malignant Glioma
Status: UNKNOWN
Conditions: Anaplastic Astrocytoma|Anaplastic Oligodendroglioma|Anaplastic Oligoastrocytoma|Glioblastoma
Interventions: DRUG: Carmustine|PROCEDURE: tumor resection surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Postprandial Effects of a Hallucinatory Meal on Appetite Regulation
Status: COMPLETED
Conditions: Change in Subjective Appetite Score (VAS)
Interventions: OTHER: hallucinated meal|OTHER: Real meal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Safety of FE 999049 in Controlled Ovarian Stimulation in Japanese Women
Status: COMPLETED
Conditions: Infertility
Interventions: DRUG: Follitropin delta|DRUG: Follitropin beta
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Pediatric Medical Emergencies' in Situ Simulations
Status: NOT_YET_RECRUITING
Conditions: Pedagogical and Psycho-social Impact of in Situ Simulation
Interventions: OTHER: Hicks self-confidence scale, Karasek survey, Maslach Burnout Inventory
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: An Integrative-"Omics" Study of Cardiomyopathy Patients for Diagnosis and Prognosis in China
Status: UNKNOWN
Conditions: Dilated Cardiomyopathy|Hypertrophic Cardiomyopathy|Arrhythmogenic Right Ventricular Cardiomyopathy|Left Ventricular Non-compaction|Restrictive Cardiomyopathy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Upper Extremity Function Before and After Hippotherapy in Children With Autism Spectrum Disorder and/or Cerebral Palsy
Status: COMPLETED
Conditions: Autism Spectrum Disorder|Cerebral Palsy
Interventions: BEHAVIORAL: Hippotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of a Digital Application for Adolescents With Mild to Moderate Anxiety
Status: NOT_YET_RECRUITING
Conditions: Anxiety|Anxiety and Fear|Adolescent - Emotional Problem
Interventions: OTHER: Modi|OTHER: Treatment as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Bilirubin Estimates in Newborns From Smartphone Digital Images in a Nepali Population
Status: COMPLETED
Conditions: Jaundice, Neonatal
Interventions: DEVICE: Picterus Jaundice Pro
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: SALT Study (Switching to the Administration of Lithium Slow -Release Treatment)
Status: TERMINATED
Conditions: Bipolar Disorder
Interventions: DRUG: Lithium sulphate prolonged-release 660 mg|DRUG: Lithium carbonate immediate-release 150 mg and 300 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Accelerating Motor Learning in Pediatrics
Status: COMPLETED
Conditions: Healthy|Pediatrics
Interventions: DEVICE: Anodal Conventional tDCS|DEVICE: Anodal High Definition tDCS|DEVICE: Sham tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Study to Assess Treat-to-Target and Dosing Flexibility of Oral Upadacitinib Tablets in Adult Participants With Moderate to Severe Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: Upadacitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PräVaNet - Structured, Intersectoral, Multiprofessional, Digitized Program to Optimize Cardiovascular Prevention
Status: ACTIVE_NOT_RECRUITING
Conditions: Type 2 Diabetes|Arteriosclerosis|Arterial Hypertension|Lipid Metabolism Disorders
Interventions: OTHER: PräVaNet-Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Behavioral Drug and HIV Risk Reduction Counseling With MMT in China
Status: COMPLETED
Conditions: Opiate Dependence
Interventions: BEHAVIORAL: Behavioral Drug and HIV Risk Reduction Counseling|BEHAVIORAL: Educational Counseling|BEHAVIORAL: Treatment as Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Duloxetine (LY248686) in Participants With Chronic Osteoarthritis and Knee Pain in Japan
Status: COMPLETED
Conditions: Osteoarthritis of the Knee
Interventions: DRUG: Duloxetine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Developing Effective Response Inhibition Training for Symptom Relief in OCD and Trichotillomania
Status: COMPLETED
Conditions: Obsessive Compulsive Disorder|Trichotillomania
Interventions: BEHAVIORAL: Response inhibition training|BEHAVIORAL: Placebo Control Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility Trial of an Online Course (eMB) to Reduce Anxiety and Depression for Pregnant Women and Their Partners
Status: COMPLETED
Conditions: Anxiety Disorders Generalized|Depression
Interventions: BEHAVIORAL: Online Mothers and Babies Course (eMB)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: An Evaluation of Weekly Tafenoquine
Status: COMPLETED
Conditions: Falciparum Parasitaemia
Interventions: DRUG: Tafenoquine|DRUG: Mefloquine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Zinc Supplementation of Imipramine Therapy
Status: COMPLETED
Conditions: Major Depression
Interventions: DIETARY_SUPPLEMENT: Zincas Forte|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pragmatic Implementation Trial of a CF Primary Palliative Care Intervention
Status: ACTIVE_NOT_RECRUITING
Conditions: Cystic Fibrosis|Quality of Life
Interventions: OTHER: Implementation of Primary Palliative Care Intervention in CF Centers
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: MNK6106 for Liver Disease (Hepatic Cirrhosis) That in the Past Has Affected the Brain (Hepatic Encephalopathy)
Status: COMPLETED
Conditions: Hepatic Cirrhosis|Hepatic Encephalopathy (HE)
Interventions: DRUG: MNK6106|DRUG: Rifaximin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Serum Levels of Janus Kinase 1 and 2 in Patients With Cholinergic Urticaria
Status: RECRUITING
Conditions: Cholinergic Urticaria
Interventions: DIAGNOSTIC_TEST: serum levels of Janus Kinase 1and 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of the Side of Interscalene Block on Bradycardia and Hypotension in Beach Chair Position
Status: UNKNOWN
Conditions: Shoulder Surgery|Beach Chair Position|Interscalene Block|Hypotension|Bradycardia|Autonomic Nervous System
Interventions: OTHER: Left interscalene block|OTHER: Right interscalene block
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparative Study of Antimicrobial Effectiveness
Status: COMPLETED
Conditions: Bacterial Microflora Reduction
Interventions: DRUG: Project X 26ml|DRUG: Project X 5.1ml|DRUG: Prevantics Maxi Swabstick
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION