pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Parcopa Versus Carbidopa-levodopa in a Single Dose Cross-over Comparison Study
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DRUG: Parcopa|DRUG: carbidopa-levodopa (Sinemet)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Determining the Potential of Wholegrain Wheat and Rye to Improve Gut HealTh
Status: UNKNOWN
Conditions: Gastrointestinal Diseases|Cardiovascular Diseases|Obesity
Interventions: OTHER: Wholegrain rye|OTHER: Wholegrain wheat|OTHER: Refined wheat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Carboplatin, Paclitaxel, and Surgery in Treating Patients With Advanced Ovarian Epithelial, Fallopian Tube, or Primary Peritoneal Cavity Cancer
Status: TERMINATED
Conditions: Fallopian Tube Cancer|Ovarian Cancer|Peritoneal Cavity Cancer
Interventions: DRUG: carboplatin|DRUG: paclitaxel|PROCEDURE: cytoreductive surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: "Core" Muscle Endurance, Upper Extremity Muscle Strength, Grip Strength, and Hand-eye Coordination in Generalized Joint Hypermobility
Status: COMPLETED
Conditions: Hypermobility, Joint|Muscle Weakness|Coordination Lack
Interventions: OTHER: Core muscle endurance|OTHER: Upper extremity muscle strength|OTHER: Grip strength|OTHER: Pinch strength|OTHER: Alternate hand-wall toss test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Multi-Disciplinary Technology-Based Care for Diabetic Ketoacidosis in Patients With Type 1 Diabetes
Status: NOT_YET_RECRUITING
Conditions: Diabetic Ketoacidosis
Interventions: DEVICE: Continuous Glucose Monitoring (CGM)|OTHER: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Influence of ABCB1、CYP3A4、CYP3A5、POR Genetic Polymorphism and Other Factors on Tacrolimus Blood Concentration
Status: UNKNOWN
Conditions: Kidney Transplantation|Liver Transplantation
Interventions: OTHER: Clinical and genetic factors
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pazopanib Versus Sunitinib in the Treatment of Asian Subjects With Locally Advanced and/or Metastatic Renal Cell Carcinoma
Status: COMPLETED
Conditions: Carcinoma, Renal Cell
Interventions: DRUG: Pazopanib|DRUG: Sunitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 1-2 XIAP Antisense AEG35156 With Carboplatin and Paclitaxel in Patients With Advanced Non-Small Cell Lung Cancer
Status: TERMINATED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: AEG35156
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Echocardiographic Changes After 3-hydroxy Butyrate+Whey Intake
Status: COMPLETED
Conditions: Cardiac Output|Endotoxemia|Catabolic State|Echocardiography
Interventions: DIETARY_SUPPLEMENT: Whey|DIETARY_SUPPLEMENT: 3-OHB + Whey
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Sildenafil to Reduce Vascular Remodeling During Left Ventricular Assist Device Support
Status: NOT_YET_RECRUITING
Conditions: Vascular Diseases
Interventions: DRUG: Sildenafil|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ABT-888 Plus Metronomic Cyclophosphamide to Treat Cancer
Status: COMPLETED
Conditions: Neoplasms|Lymphoma
Interventions: DRUG: ABT-888|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Acupuncture on the Microbiota-gut-brain Axis in Crohn's Disease
Status: COMPLETED
Conditions: Crohn Disease
Interventions: OTHER: Acupuncture treatment|OTHER: Sham acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect on Exercise Endurance and Lung Hyperinflation of Tiotropium + Olodaterol in COPD Patients
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Placebo|DRUG: Tiotropium|DRUG: Olodaterol|DRUG: tiotropium + olodaterol|DRUG: Tiotropium + Olodaterol|DEVICE: Respimat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: 'ADVANCE' (A Pilot Trial)
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Paclitaxel|DRUG: Cyclophosphamide|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single Dose Pharmacokinetics of Intranasal Fluticasone Delivered by a Fixed Combination With Azelastine (MP29 02) in Comparison to Two Different Fluticasone Nasal Sprays
Status: COMPLETED
Conditions: Allergic Rhinitis
Interventions: DRUG: Azelastine, Fluticasone|DRUG: Fluticasone mono|DRUG: Fluticasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Supplementation of Thyroid Hormone for TSH Control in Patients With Chronic Kidney Disease Without TRR.
Status: COMPLETED
Conditions: Chronic Kidney Diseases|Subclinical Hypothyroidism
Interventions: DRUG: Levothyroxine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Benefit of Virtual Reality Headset Use on Apathy in Older Adults With Major Neurocognitive Disorders
Status: RECRUITING
Conditions: Apathy in Dementia|Aged|Virtual Reality|Neurocognitive Disorders
Interventions: DEVICE: Casque Lumeen
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phase 1-2 Study of Deoxycholic Acid Injection (ATX-101) for the Reduction of Submental Fat
Status: COMPLETED
Conditions: Moderate or Severe Submental Fullness
Interventions: DRUG: Deoxycholic Acid Injection|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Occult Paroxysmal Atrial Fibrillation in Non-Cryptogenic Ischemic Stroke
Status: COMPLETED
Conditions: Ischemic Stroke
Interventions: DEVICE: Reveal LINQ Insertable Cardiac Monitor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study Comparing the Pharmacodynamic Properties of Insulin VIAJECT™, Regular Human Insulin, and Insulin Lispro
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: DRUG: Regular Human Insulin|DRUG: Lispro|DRUG: VIAject|DRUG: VIAject 50%|DRUG: VIAject/Insulin Glargine|DRUG: Insulin Glargine/VIAject
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Aminophylline on Renal Function and Urine Volume of AKI Patient
Status: UNKNOWN
Conditions: Acute Kidney Injury
Interventions: DRUG: aminophylline|DRUG: frusemide|DRUG: normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of MF59C.1 Adjuvanted Trivalent Subunit Influenza Vaccine in Elderly Subjects
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: MF59 adjuvanted trivalent subunit influenza vaccine (aTIV)|BIOLOGICAL: Non-adjuvanted trivalent subunit influenza vaccine (TIV)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: NOV-002, Doxorubicin, Cyclophosphamide, and Docetaxel in Women With Newly Diagnosed Stage II or IIIC Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Cyclophosphamide|DRUG: Docetaxel|DRUG: Doxorubicin|DRUG: NOV 002
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Rituximab in the Treatment of Good Prognosis Microscopic Polyangiitis
Status: UNKNOWN
Conditions: Microscopic Polyangiitis (MPA)
Interventions: DRUG: Rituximab|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Oral EPI-7386 in Patients With Castration-Resistant Prostate Cancer
Status: RECRUITING
Conditions: Prostate Cancer
Interventions: DRUG: EPI-7386 (QD)|DRUG: EPI-7386 (BID)|DRUG: Abiraterone acetate|DRUG: Apalutamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Galactose Supplementation for the Treatment of MOGHE
Status: UNKNOWN
Conditions: Refractory Epilepsy|SLC35A2-CDG - Solute Carrier Family 35 Member A2 Congenital Disorder of Glycosylation
Interventions: DIETARY_SUPPLEMENT: D-Galactose
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomised Controlled Trial for Assessing the Effectiveness of an Inclusive Heart Failure Monitoring and TRACKing Solution in the UK.
Status: NOT_YET_RECRUITING
Conditions: Heart Failure
Interventions: DEVICE: Heartfelt Device installed|OTHER: Standard care|OTHER: Questionnaires|DEVICE: Heartfelt Device in pharmacy|DEVICE: Heartfelt device alerting system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Crossover Study of Neuropsychological Effects of Lacosamide and Carbamazepine Immediate Release in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Lacosamide (LCM)|DRUG: Carbamazepine Immediate Release (CBZ-IR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Perioperative vs Postoperative Chemotherapy + Bevacizumab in Colorectal Cancer, Liver Mets
Status: COMPLETED
Conditions: Colorectal Cancer|Liver Metastasis
Interventions: DRUG: Bevacizumab, mFOLFOX, FOLFIRI|DRUG: Bevacizumab, mFOLFOX, FOLFIRI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Role of Dopamine, Serotonin and 5-HT2A Receptors in Emotion Processing
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: LSD|DRUG: MDMA|DRUG: Amphetamine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Multimodal Pain Management After Robotic-Assisted Total Laparoscopic Hysterectomy
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: DRUG: Gabapentin|DRUG: Acetaminophen|DRUG: Celecoxib|DRUG: Ketorolac|PROCEDURE: Paracervical block with ropivacaine|PROCEDURE: Local anesthetic injection with ropivacaine at abdominal laparoscopic port sites|DRUG: Hydromorphone|DRUG: Oxycodone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Modafinil for the Treatment of Fatigue in Lung Cancer V9.0
Status: COMPLETED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: Modafinil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of BRL29060A (Paroxetine Hydrochloride Hydrate) in Posttraumatic Stress Disorder (PTSD)
Status: TERMINATED
Conditions: Post-Traumatic Stress Disorder|Stress Disorders, Post-Traumatic
Interventions: DRUG: paroxetine|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Lometrexol Plus Folic Acid in Treating Patients With Stage IIIB or Stage IV Non-Small Cell Lung Cancer
Status: UNKNOWN
Conditions: Lung Cancer
Interventions: DIETARY_SUPPLEMENT: folic acid|DRUG: lometrexol
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: A Study of Pamiparib Combined With Abiraterone Acetate in Neoadjuvant Treatment of Prostate Cancer
Status: RECRUITING
Conditions: Neoadjuvant Therapy
Interventions: DRUG: pamiparib|DRUG: abiraterone|DRUG: prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Supportive Care Intervention In Patients Hospitalized For Hematopoietic Stem Cell Transplantation (Shield)
Status: COMPLETED
Conditions: Complication of Transplant
Interventions: OTHER: transplant with early palliative care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Vyvanse on Sleep in Children Aged 6-12 Years With Attention Deficit Hyperactivity Disorder (ADHD)
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder|Sleep
Interventions: DRUG: lisdexamfetamine dimesylate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of Relaxation to 12 Weeks Against Placebo in the Overall Care Chronic Pain in Patients With Fibromyalgia
Status: COMPLETED
Conditions: Fibromyalgia
Interventions: BEHAVIORAL: Active relaxation|BEHAVIORAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effects of WBV Associated With IMT on Inflammatory Markers, Body Composition, Muscle Strength and Thickness
Status: COMPLETED
Conditions: Frail Elderly Syndrome
Interventions: OTHER: WBV + IMT|OTHER: WBV + IMTsham|OTHER: WBVsham + IMTsham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Valsartan and Aliskiren on Hemostatic Indices in Hypertensive Diabetics
Status: UNKNOWN
Conditions: Diabetes Mellitus
Interventions: DRUG: Aliskiren + Valsartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Subomohyoid vs Costoclavicular Block in Shoulder Surgery
Status: COMPLETED
Conditions: Shoulder Pain
Interventions: OTHER: Sub-omohyoidal Plane Block|OTHER: Cervical Plexus Block|OTHER: Costoclavicular Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Pharmacokinetics of Dolutegravir in Pregnant HIV Mothers and Their Neonates: A Pilot Study
Status: COMPLETED
Conditions: HIV|Pregnancy
Interventions: DRUG: Dolutegravir 50mg od|DRUG: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Open-Label Extension Study of the Effectiveness and Safety of the Investigational Compound RWJ-333369 in Patients With Epilepsy
Status: COMPLETED
Conditions: Epilepsy|Epilepsies, Partial
Interventions: DRUG: RWJ 333369
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combined Effects Of Autogenic Drainage and Segmental Breathing Techniques in Chronic Obstructive Pulmonary Disease
Status: RECRUITING
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: OTHER: Segmental breathing technique|OTHER: autogenic drainage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Fractional Flow Reserve-Guided Percutaneous Coronary Intervention and Coronary Artery Bypass Graft Surgery in Patients With Multivessel Coronary Artery Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Coronary Disease|Coronary Stenosis
Interventions: PROCEDURE: FFR guided PCI|PROCEDURE: CABG|DEVICE: Resolute Integrity Stent|DEVICE: Resolute Onyx Stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neurotrophic Indicators of Cognition, Executive Skills, Plasticity, and Adverse Childhood Experiences Study
Status: COMPLETED
Conditions: Weight Loss|Wait-List Control
Interventions: BEHAVIORAL: Stress reactivity stimuli
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Surgical Treatment of DDH With and Without Capsulorrhaphy
Status: NOT_YET_RECRUITING
Conditions: Developmental Dysplasia of the Hip
Interventions: PROCEDURE: DDH with capsulorrhaphy|PROCEDURE: DDH without capsulorrhaphy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Efficacy of VUM02 Injection in Treatment of Idiopathic Pulmonary Fibrosis (IPF)
Status: RECRUITING
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: DRUG: VUM02 Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testing a Mobile App to Improve Toothbrushing Skills and Habits in Teens With Autism
Status: RECRUITING
Conditions: Autism
Interventions: BEHAVIORAL: Testing a Mobile App to Improve Toothbrushing Skills and Habits in Teens With Autism
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy of Doravirine, Tenofovir, Lamivudine (MK-1439A) in Participants Infected With Treatment-Naïve Human Immunodeficiency Virus (HIV) -1 With Transmitted Resistance (MK-1439A-030)
Status: COMPLETED
Conditions: HIV-1 Infection
Interventions: DRUG: Doravirine/lamivudine/tenofovir disoproxil fumarate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of [18F]PSMA-1007 Injection in Suspected Persistent or Recurrent Prostate Cancer.
Status: COMPLETED
Conditions: Prostate Cancer Recurrent|Recurrent Prostate Cancer
Interventions: DIAGNOSTIC_TEST: [18F] PSMA-1007 Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: (VOYAGER) Study of Avapritinib vs Regorafenib in Patients With Locally Advanced Unresectable or Metastatic GIST
Status: COMPLETED
Conditions: GIST
Interventions: DRUG: avapritinib|DRUG: regorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of Exercise in Patients With Spinal Muscular Atrophy (SMA)
Status: COMPLETED
Conditions: Spinal Muscular Atrophy|Neuromuscular Disease
Interventions: OTHER: Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transcranial Photobiomodulation for Adult ADHD
Status: NOT_YET_RECRUITING
Conditions: ADHD
Interventions: DEVICE: Niraxx G1 Headband Device including sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fractionated Stereotactic Radiotherapy (FSRT) in Treatment of Brain Metastases
Status: TERMINATED
Conditions: Brain Metastases|Generalized Malignancy, Primary|Brain Lesions
Interventions: DRUG: TPI 287|PROCEDURE: Fractionated Stereotactic Radiotherapy (FSRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of the NaviAid™ G-Eye System During Colonoscopy
Status: COMPLETED
Conditions: Colorectal Cancer|Polyp|Adenoma
Interventions: DEVICE: NaviAid™ G-Eye procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Trial of Local Cystoscopic Injection of Tremelimumab Plus Systemic Durvalumab for High Risk Non-Muscle Invasive Bladder Cancer
Status: WITHDRAWN
Conditions: Bladder Cancer|High-Risk Cancer|Tremelimumab|Durvalumab|Non-muscle Invasive
Interventions: DRUG: Tremelimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tranexamic Acid for Anaemia Trial
Status: NOT_YET_RECRUITING
Conditions: Anemia
Interventions: DRUG: Tranexamic Acid 500 MG|OTHER: Matched placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Gossypol in Treating Patients With Progressive or Recurrent Glioblastoma Multiforme
Status: COMPLETED
Conditions: Adult Giant Cell Glioblastoma|Adult Glioblastoma|Adult Gliosarcoma|Recurrent Adult Brain Tumor
Interventions: DRUG: R-(-)-gossypol acetic acid|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Additive Effects of Intra-arterial Tenecteplase for Successful Thrombectomy Due to Acute Basilar Artery Occlusion
Status: NOT_YET_RECRUITING
Conditions: Basilar Artery Occlusion|Thrombectomy|Tenecteplase
Interventions: DRUG: Tenecteplase for Injection|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Obinutuzumab(GA101) in Combination With High-Dose Methylprednisolone(HDMP) in Chronic Lymphocytic Leukemia(CLL) Patients (GA101 & HDMP)
Status: ACTIVE_NOT_RECRUITING
Conditions: CLL
Interventions: DRUG: GA101/HDMP
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Salivary and Faecal Microbiome of Recurrent Aphthous Stomatitis Patients Before and After Treatment With Probiotics
Status: COMPLETED
Conditions: Recurrent Aphthous Ulcers
Interventions: DIETARY_SUPPLEMENT: Probiotic lozenge
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Maintenance With Selinexor/Placebo After Combination Chemotherapy in Participants With Endometrial Cancer [SIENDO]
Status: ACTIVE_NOT_RECRUITING
Conditions: Endometrial Cancer
Interventions: DRUG: Selinexor|DRUG: Matching placebo for selinexor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparator Study of PEG 3350 Versus Prucalopride in Females With Chronic Constipation
Status: COMPLETED
Conditions: Constipation
Interventions: DRUG: PEG 3350 plus electrolytes|DRUG: Prucalopride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nitrofurantoin Prophylaxis During Catheter-managed Acute Urinary Retention After Pelvic Reconstructive Surgery
Status: COMPLETED
Conditions: Pelvic Organ Prolapse
Interventions: DRUG: Nitrofurantoin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Bowel Management Program (Retrograde Rectal Enema) for the Treatment of Low Anterior Resection Syndrome in Rectal Cancer Patients
Status: NOT_YET_RECRUITING
Conditions: Low Anterior Resection Syndrome|Rectal Carcinoma
Interventions: DIETARY_SUPPLEMENT: Dietary Fiber|PROCEDURE: Enema Administration|DRUG: Loperamide Hydrochloride|PROCEDURE: Physical Therapy|OTHER: Questionnaire Administration|PROCEDURE: X-Ray Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Virtual Reality Based Sensorimotor Speech Therapy
Status: COMPLETED
Conditions: Broca's Aphasia
Interventions: BEHAVIORAL: VR-based sensorimotor aphasia therapy|BEHAVIORAL: Control Group (conventional aphasia rehabilitation)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Standard Treatment +/- SBRT in Solid Tumors Patients With Between 1 and 5 Bone-only Metastases
Status: RECRUITING
Conditions: Metastatic Breast Cancer|Metastatic Lung Cancer|Metastatic Prostate Cancer|Bone Metastases
Interventions: RADIATION: SBRT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Liposomal Bupivacaine in Total Shoulder Arthroplasty
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Liposomal bupivacaine|PROCEDURE: Inter-scalene nerve block|DRUG: Ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of IV-Administered Ca-DTPA and Zn-DTPA To Treat Patients With Gadolinium Deposition Disease
Status: TERMINATED
Conditions: Headache|Cognitive Disturbance|Skin Hyperpigmentation|Arthralgia
Interventions: DRUG: Calcium DTPA|DRUG: Zinc DTPA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect Of Single-Dose PF-05175157 On Metabolic And Cardiopulmonary Parameters
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: PF-05175157|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Performance Evaluation of mIntense L+AS 25 mg/ml Hyaluronic Acid for the Correction of Moderate to Deep Wrinkles and Folds
Status: COMPLETED
Conditions: Skin Aging|Skin Wrinkling
Interventions: DEVICE: mIntense L+AS
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: School-Based Tele-Physiatry Assistance for Rehabilitative and Therapeutic Services
Status: COMPLETED
Conditions: Pediatrics|Physical and Rehabilitation Medicine|Physical Therapy Modalities
Interventions: OTHER: Telemedicine|OTHER: In-Person Pediatric Physiatrist|OTHER: In-Person Non-Pediatric Physiatrist
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Drug-Drug Interaction Study Between AZD9668 and Warfarin to Study the Effect of AZD9668 on the Metabolism and Effect of Warfarin
Status: WITHDRAWN
Conditions: Pharmacokinetics|Pharmacodynamics
Interventions: DRUG: AZD9668|DRUG: Warfarin
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Blockbuster LMA Versus Baska Mask in Laparoscopic Cholecystectomy
Status: RECRUITING
Conditions: Blockbuster LMA|Baska Mask|Laparoscopic Cholecystectomy
Interventions: DEVICE: Blockbuster LMA|DEVICE: Baska Mask
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Pilot Bioequivalence Study Between Fluticasone Propionate 250 mcg and Salmeterol Xinafoate 50 mcg Inhalation Powder/Respirent Pharmaceuticals vs. ADVAIR DISKUS® 250/50 Inhalation Powder/GSK in Healthy Volunteers
Status: COMPLETED
Conditions: Bioequivalence
Interventions: DRUG: Fluticasone propionate 250 mcg and salmeterol xinafoate 50 mcg/Respirent|DRUG: ADVAIR DISKUS® 250/50
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Comparative Bioequivalence Study in Adult Patients Suffering From Chronic Myeloid Leukemia & Gastrointestinal Stromal Tumor Under Fed Conditions
Status: COMPLETED
Conditions: Chronic Myeloid Leukemia|Gastrointestinal Stromal Tumor
Interventions: DRUG: Imatinib Mesylate Tablets, 400 mg|DRUG: Imatinib Mesylate Tablets, 400 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Early Skin-to-Skin Contact in Normal Births on Suction Sufficiency, Stress and Bilirubin Levels of Newborns
Status: COMPLETED
Conditions: Nurse's Role|Breastfeeding
Interventions: BEHAVIORAL: Skin-to-Skin contact.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study Evaluating Efficiency and Tolerance of High-dose Fluconazole Associated With Flucytosine as Induction Therapy for Cryptococcal Meningitis Associated With HIV in Sub-saharan Africa
Status: UNKNOWN
Conditions: Cryptococcal Meningitis|HIV
Interventions: DRUG: Fluconazole|DRUG: Flucytosine|PROCEDURE: lumbar punctures
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Session Frequency of rESWT on Gastrocnemius Muscle Spasticity in Children With Spastic Type Cerebral Palsy
Status: COMPLETED
Conditions: Spasticity, Muscle|Cerebral Palsy|Child; Spastic
Interventions: DEVICE: radial Extracorporeal Shockwave Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Safety and Efficacy of Recombinant Human Luteinizing Hormone (r-hLH) Compared With Urinary Human Chorionic Gonadotrophin (u-hCG) to Trigger Ovulation in Infertile Women
Status: COMPLETED
Conditions: Infertility
Interventions: DRUG: r-hFSH|DRUG: r-hLH|DRUG: u-hCG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral Anticoagulation in Hemodialysis
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DRUG: Rivaroxaban 10 MG Oral Tablet|DIETARY_SUPPLEMENT: MK-7 2000µg thrice weekly|DRUG: Vitamin K Antagonist - Drug
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: 50% Nitrous Oxide and 50% Oxygen (MEOPA) Conscious Sedation Versus Placebo in Fiberoptic Bronchoscopy
Status: UNKNOWN
Conditions: Fiberoptic Bronchoscopy
Interventions: DRUG: 50% Nitrous Oxide and 50% Oxygen (MEOPA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: The PALP™-COPD Trial (Low-Flow CO2-Removal (ECCO2-R) in Exacerbated COPD)
Status: WITHDRAWN
Conditions: COPD|Chronic Obstructive Pulmonary Disease
Interventions: DEVICE: CO2-Removal (PALP-Device/MaquetCP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cisplatin and Flavopiridol in Treating Patients With Advanced Ovarian Epithelial Cancer or Primary Peritoneal Cancer
Status: COMPLETED
Conditions: Recurrent Ovarian Epithelial Cancer|Recurrent Primary Peritoneal Cavity Cancer|Stage IIIA Ovarian Epithelial Cancer|Stage IIIA Primary Peritoneal Cavity Cancer|Stage IIIB Ovarian Epithelial Cancer|Stage IIIB Primary Peritoneal Cavity Cancer|Stage IIIC Ovarian Epithelial Cancer|Stage IIIC Primary Peritoneal Cavity Cancer|Stage IV Ovarian Epithelial Cancer|Stage IV Primary Peritoneal Cavity Cancer
Interventions: DRUG: cisplatin|DRUG: alvocidib|DRUG: cisplatin/flavopiridol
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Efficiency Impact of Conducting Active Temperature Management During Cardiac Cryoablation Procedures
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DEVICE: Esophageal warming device (Attune Medical, Chicago, IL
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Xenetix® 350: Comparative Assessment of Image Quality for Coronary CT Angiography
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DRUG: iobitridol|DRUG: iopromide|DRUG: iomeprol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of GNS561 in Patients With Liver Cancer
Status: TERMINATED
Conditions: Hepatocellular Carcinoma|Cholangiocarcinoma, Intrahepatic
Interventions: DRUG: GNS561
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improving Voice Production for Adults With Age-related Dysphonia
Status: ENROLLING_BY_INVITATION
Conditions: Presbylarynx|Age-Related Dysphonia
Interventions: BEHAVIORAL: Voice therapy: respiratory|BEHAVIORAL: Voice therapy: glottal closure|BEHAVIORAL: Voice therapy: loud|BEHAVIORAL: Voice therapy: Semiocclusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Levamisole and Isoprinosine in Immune-prophylaxis of Egyptian Healthcare Workers Facing COVID-19
Status: UNKNOWN
Conditions: Coronavirus Disease (COVID-19)
Interventions: DRUG: Levamisole|DRUG: Isoprinosine|DRUG: Levamisole and Isoprinosine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effectiveness of Temporomandibular Joint Mobilization and Exercise in Individuals With Chronic Neck Pain
Status: COMPLETED
Conditions: Temporomandibular Joint Disorders|Temporomandibular Joint Dysfunction Syndrome|Neck Pain|Chronic Pain
Interventions: OTHER: physiotherapy|OTHER: TMJ exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Long-Term Tetrahydrobiopterin Treatment in PKU Patients of 0-18 Years - Study on Phenylalanine Tolerance and Safety
Status: TERMINATED
Conditions: Phenylalanine Hydroxylase Deficiencies
Interventions: DRUG: tetrahydrobiopterin (BH4)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Safety and Pharmacokinetics Study of DU-176b Administered to Non-valvular Atrial Fibrillation With Severe Renal Impairment
Status: COMPLETED
Conditions: Non-valvular Atrial Fibrillation
Interventions: DRUG: DU-176b 15mg|DRUG: DU-176b 30mg|DRUG: DU-176b 60mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Culinary Medicine for Cancer Caregivers
Status: NOT_YET_RECRUITING
Conditions: Pediatric Cancer|Caregiver Burden|Cancer, Treatment-Related|Nutrition Aspect of Cancer
Interventions: BEHAVIORAL: Let's Cook Together
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pathway to Detection & Differentiation of Delirium & Dementia in the Emergency Department
Status: COMPLETED
Conditions: Cognitive Impairment|Emergency Care|Dementia|Delirium
Interventions: DIAGNOSTIC_TEST: PD4ED 3-step intervention (ED assessment, outpatient assessment, Brain health plan)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Monoclonal Antibody Therapy in Treating Patients With Leptomeningeal Cancer
Status: COMPLETED
Conditions: Brain and Central Nervous System Tumors|Intraocular Melanoma|Lung Cancer|Melanoma (Skin)|Neuroblastoma|Retinoblastoma|Sarcoma
Interventions: RADIATION: iodine I 131 monoclonal antibody 3F8
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Evaluation of Efficacy and Safety of Oral Minoxidil 1 mg in Female Androgenetic Alopecia
Status: NOT_YET_RECRUITING
Conditions: Androgenetic Alopecia|Female Pattern Baldness
Interventions: DRUG: Minoxidil Tablets|DRUG: Minoxidil Topical|DRUG: Placebo oral tablet|DRUG: Vehicle solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ziprasidone for the Treatment of Mania in Children and Adolescents With Bipolar Disorder
Status: COMPLETED
Conditions: Bipolar Disorder|Mania
Interventions: DRUG: ziprasidone (Geodon)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Pressure Distribution of Kyboot Shoes in Comparison to Other Foot Wear
Status: COMPLETED
Conditions: Diabetes Mellitus Type 2|Sensory Neuropathy|Foot Ulcer, Diabetic
Interventions: DEVICE: Kyboot shoes
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Combination Therapy of L19IL2 and Gemcitabine in Advanced Pancreatic Cancer Patients
Status: TERMINATED
Conditions: Pancreatic Cancer Patients Diagnosed With Locally Advanced or Metastatic Pancreatic Cancer Not Amenable to Curative Surgical Resection
Interventions: DRUG: L19IL2 monoclonal antibody-cytokine fusion protein in combination with gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Study of High Frequency Percussive Ventilation With Conventional Ventilation
Status: WITHDRAWN
Conditions: Respiratory Distress Syndrome, Adult|Pneumonia|Mechanical Ventilation
Interventions: DEVICE: High Frequency Percussive Ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Noninvasive Positive Pressure Ventilation in Moderate Acute Respiratory Distress Syndrome
Status: COMPLETED
Conditions: Acute Respiratory Distress Syndrome
Interventions: PROCEDURE: noninvasive positive pressure ventilation (NPPV)|PROCEDURE: invasive mechanical ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of a WeChat-based Alcohol Consumption Intervention Mini-program ("Sober Time ACT") in China
Status: RECRUITING
Conditions: Alcohol Use Disorder|Alcohol Abuse
Interventions: DEVICE: Sober Time ACT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Total Intravenous Anesthesia With Propofol vs. General Anesthesia in Outpatient Shoulder Arthroscopic Surgeries
Status: ENROLLING_BY_INVITATION
Conditions: Rotator Cuff Tears|Rotator Cuff Injuries|Orthopedic Disorder|Sports Injury|Anesthesia
Interventions: DRUG: TIVA with Propofol|DRUG: Inhaled Anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Perioperative Continuation of Metformin Therapy in Patients With Typ 2 Diabetes Mellitus Undergoing Non-cardiac Surgery
Status: UNKNOWN
Conditions: Hyperglycemia|Metformin|Type 2 Diabetes|Hyperlactatemia
Interventions: DRUG: Metformin Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Can Oxytocin Enhance the Placebo Effect?
Status: COMPLETED
Conditions: Oxytocin Effect on Memory Performance During Phase 1|Oxytocin Effect on Memory Performance During Phase 2|Oxytocin Effect on Memory Performance During Phase 3|Oxytocin Effect on Memory Performance During Phase 4
Interventions: DRUG: Oxytocin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Prospective Cohort Study of Accelerated Resolution Therapy (ART) for Treatment of Military Psychological Trauma
Status: COMPLETED
Conditions: Post-traumatic Stress Disorder (PTSD)
Interventions: BEHAVIORAL: Accelerated Resolution Therapy (ART)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low Intensity Focused Ultrasound for Learning and Memory and Emotion Regulation
Status: COMPLETED
Conditions: Brain Diseases|Memory Disorders|Learning Disabilities|Cognitive Impairment
Interventions: DEVICE: Low Intensity Focused Ultrasound Pulsation to Amygdala|DEVICE: Low Intensity Focused Ultrasound Pulsation to Entorhinal Cortex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Trial to Assess the Effects of Different Trans-fatty Acids on Endothelial Function in Humans
Status: TERMINATED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: diet enriched with industrial trans fatty acids|DIETARY_SUPPLEMENT: diet enriched with ruminant trans fatty acids|DIETARY_SUPPLEMENT: diet without any trans fatty acids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Danshen-Jiang-Fu Granule Prepared by Danshen From Different Producing Areas for Primary Dysmenorrhea
Status: COMPLETED
Conditions: Primary Dysmenorrhea|Traditional Chinese Medicine
Interventions: DRUG: Shandong Danshen-Jiang-Fu Granule|DRUG: Sichuan Danshen-Jiang-Fu Granule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: French Linguistic and Metric Validations of Parent-proxy QOL Chronic Cough Specific Questionnaire (PC-QOL)
Status: COMPLETED
Conditions: Chronic Cough
Interventions: OTHER: parent-proxy QoL chronic cough specific questionnaire (PC-QOL)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Compare the Efficacy of Levocetirizine and Montelukast to Placebo in Reducing Seasonal Allergic Rhinitis (SAR) Symptoms in Ragweed Sensitive Subjects
Status: COMPLETED
Conditions: Rhinitis, Allergic, Seasonal
Interventions: DRUG: Placebo|DRUG: Montelukast|DRUG: Levocetirizine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Collection of Serum Samples From Children and Older Adults Receiving the 2019-2020 Formulations of Fluzone® Quadrivalent and Fluzone® High-Dose Influenza Vaccines, Respectively
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Fluzone Quadrivalent vaccine, no preservative (0.5-mL), 2019-2020 formulation|BIOLOGICAL: Fluzone High-Dose vaccine, 2019-2020 formulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Efficacy and Safety Profiles of Combination Sedation Propofol With Midazolam and Meperidine.
Status: COMPLETED
Conditions: Disorders of Gallbladder, Biliary Tract and Pancrease
Interventions: DRUG: Propofol|DRUG: Midazolam|DRUG: Meperidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Study In Subjects With COPD (Chronic Obstructive Pulmonary Disease)
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: cilomilast
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Acute Effect of Photobiomodulation Therapy on Muscle Performance in Female Futsal Players
Status: COMPLETED
Conditions: Muscle Performance|Photobiomodulation Therapy
Interventions: DEVICE: Placebo|DEVICE: 300 J|DEVICE: 600 J|DEVICE: 1260 J
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Ibuprofen 5% Topical Gel CIPT
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Ibuprofen 5% topical gel|DRUG: Topical gel vehicle|DRUG: Sodium lauryl sulfate 0.2%|DRUG: Sodium chloride solution 0.9% (saline)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Non-interventional, Post Marketing Surveillance (PMS) Study of Tresiba® (Insulin Degludec) to Evaluate Long Term Safety and Efficacy in Patients With Diabetes Mellitus in Routine Clinical Practice in India
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 1|Diabetes Mellitus, Type 2
Interventions: DRUG: insulin degludec
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p