pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Feasibility and Acceptability of HOLOBalance Compared to Standard Care in Older Adults at Risk for Falls
Status: UNKNOWN
Conditions: Accidental Falls|Aging|Vestibular Disorder
Interventions: DEVICE: HOLOBalance|OTHER: OTAGO Home Exercise Programme
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: To Assess the Safety, Tolerability and Pharmacokinetics of AZD5634 Following Inhaled and Intravenous (IV)Dose Administration
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: AZD5634 for inhalation|DRUG: AZD5634 for infusion|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Erlotinib Before and After Surgery in Treating Patients With Muscle-Invasive Bladder Cancer
Status: COMPLETED
Conditions: Bladder Cancer
Interventions: DRUG: Erlotinib|PROCEDURE: Radical Cystectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Intravenous Versus Intrathecal Dexamethazone on Postdural Puncture Headache
Status: UNKNOWN
Conditions: Postdural Puncture Headache
Interventions: DRUG: Dexamethasone intravenous|DRUG: Dexamethasone intrathecal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Auricular Vagal Nerve Stimulation for Hypermobile Ehlers-Danlos Syndrome
Status: RECRUITING
Conditions: Functional Gastrointestinal Disorders|Hypermobile Ehlers-Danlos Syndrome|Postural Orthostatic Tachycardia Syndrome|Autonomic Nervous System Disease|Autonomic Nervous System Imbalance
Interventions: DEVICE: Percutaneous vagal nerve stimulation (pVNS) device|OTHER: Acoustic vagal nerve stimulation (aVNS) treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Booster Dose of COVID-19 Vaccine for Kidney Transplant Recipients Without Adequate Humoral Response
Status: UNKNOWN
Conditions: COVID-19 Acute Respiratory Distress Syndrome|Immunosuppression
Interventions: BIOLOGICAL: The Pfizer mRNA-based BNT162b2 vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Vyvanse on Driving in Young Adults With ADHD
Status: COMPLETED
Conditions: Attention Deficit/Hyperactivity Disorder(ADHD)
Interventions: DRUG: Vyvanse|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Isolated Systolic Hypertension in the Elderly and Very Elderly
Status: COMPLETED
Conditions: Isolated Systolic Hypertension
Interventions: DRUG: olmesartan medoxomil + hydrochlorothiazide, if necessary|DRUG: nitrendipine + hydrochlorothiazide, if necessary
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Imatinib Mesylate After a Donor Stem Cell Transplant in Treating Patients With Philadelphia Chromosome-Positive Leukemia
Status: COMPLETED
Conditions: Leukemia
Interventions: DRUG: imatinib mesylate|PROCEDURE: adjuvant therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of RiMO-301 and Radiotherapy With PD-1 Inhibitor for the Treatment of Head-Neck Cancer
Status: RECRUITING
Conditions: Head Neck Cancer|Intratumoral Injection
Interventions: DRUG: RiMO-301
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exposure, Relaxation, & Rescripting Therapy-Child
Status: COMPLETED
Conditions: Nightmares Associated With Trauma and Stress
Interventions: BEHAVIORAL: Exposure, Relaxation, & Rescripting Therapy-Child
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Preoperative Counseling on Patient Fear From Visual Experience During Vitrectomy Surgery Under Regional Anesthesia
Status: COMPLETED
Conditions: Any Patients Undergoing Vitrectomy Under Local Anaesthesia
Interventions: BEHAVIORAL: Counselling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Immunotherapy Versus Chemotherapy as Adjuvant Therapy for Colon Cancer With MSI-H or POLE/ POLD1 Mutations
Status: RECRUITING
Conditions: Immunotherapy|Adjuvant Therapy|Colon Cancer|MSI-H
Interventions: DRUG: Tirelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: G.R.I.T. - Goal-directed Resilience Intervention Training
Status: COMPLETED
Conditions: Chronic Post-Traumatic Stress Disorder
Interventions: BEHAVIORAL: Intervention Training|BEHAVIORAL: Control Condition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: The Effect of Vitamin c on Preventing Complex Regional Pain Syndrome (CRPS Type I) Following Ankle Fracture
Status: UNKNOWN
Conditions: Ankle Fracture
Interventions: DIETARY_SUPPLEMENT: vitamin c|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Cognitive Remediation and Supported Education in Psychotic Disorders
Status: SUSPENDED
Conditions: Psychotic Disorders
Interventions: BEHAVIORAL: Cognitive remediation therapy (CR)|BEHAVIORAL: Supported education (SE)|OTHER: Treatment as usual (TAU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: To Determine The Efficacy and Safety of GDC-0449 in Patients With Basal Cell Nevus Syndrome (BCNS)
Status: COMPLETED
Conditions: Basal Cell Nevus Syndrome|Gorlin Syndrome
Interventions: DRUG: GDC-0449
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Endoscopic Ultrasound-guided Celiac Plexus Neurolysis in the Management of Pain in Abdominal Non-pancreatic Malignancies
Status: WITHDRAWN
Conditions: Pain|Cancer
Interventions: PROCEDURE: EUS-guided Celiac Plexus Neurolysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Dual Injection ESPB Versus Single Injection ESPB for Laparotomies
Status: COMPLETED
Conditions: Post Operative Pain|Regional Block
Interventions: PROCEDURE: single level|PROCEDURE: dual level
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Factors Predicting Efficacy of Allergen Injection Immunotherapy for Grass Pollen Hayfever
Status: COMPLETED
Conditions: Rhinitis, Allergic, Seasonal
Interventions: BIOLOGICAL: Active injections of alum-adsorbed grass pollen vaccine (Alutard SQ).|OTHER: Placebo Injection|PROCEDURE: Venepuncture: 100ml blood sample taken on 12 separate visits
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: ARTEMIS-006: HS-20093 in Patients With Head and Neck Squamous Cell Carcinoma and Other Solid Tumors
Status: RECRUITING
Conditions: Head and Neck Squamous Cell Carcinoma
Interventions: DRUG: HS-20093
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preoperative Aspirin and Benzydamine Hydrochloride Gargles on Severity and Duration of Post-Operative Sore Throat
Status: UNKNOWN
Conditions: Sore Throat
Interventions: DRUG: Benzydamine hydrochloride|DRUG: Aspirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Zirconia Versus Lithium Di-silicate Overlays for Restoring Hypomineralized Molars Affected With MIH
Status: COMPLETED
Conditions: Molar Incisor Hypomineralization
Interventions: PROCEDURE: overlay
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial on Subacute Low Back Pain
Status: COMPLETED
Conditions: Subacute Low Back Pain
Interventions: PROCEDURE: Stay-active care|PROCEDURE: Stay-active care+stretching|PROCEDURE: Stay-active+stretching+manual therapy|PROCEDURE: Stay-active+stretching+manual therapy+steroid injections
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of ∆-9-THC and Naloxone in Humans
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Naloxone|DRUG: Delta-9-THC|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Postoperative Peripheral Nerve Stimulation for Management of Post-amputation Pain
Status: COMPLETED
Conditions: Phantom Limb Pain|Postoperative Pain|Neuroma|Acute Pain|Chronic Pain|Residual Limbs|Amputation
Interventions: DEVICE: Peripheral nerve stimulation|OTHER: Standard Medical Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Feasibility Study of IM OXT on Fear of Pain and Trust in Physical Therapist During OP Rehabilitation After TKA
Status: WITHDRAWN
Conditions: Osteoarthritis, Knee
Interventions: DRUG: Oxytocin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of the Efficacy and Safety of Locally Administered HTX-011 for Postoperative Analgesia Following Bunionectomy
Status: COMPLETED
Conditions: Postoperative Pain|Bunions
Interventions: DRUG: HTX-011A|BIOLOGICAL: Saline Placebo|DRUG: HTX-011B|DRUG: HTX-002|DRUG: Bupivacaine HCl|DRUG: HTX-009
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of MBG453 in Combination With Azacitidine and Venetoclax in AML Patients Unfit for Chemotherapy
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: MBG453|DRUG: Venetoclax|DRUG: Azacitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevention of Umbilical Port-site Hernia After Laparoscopic Cholecystectomy Using a Prosthetic Mesh Versus Simple Suture
Status: COMPLETED
Conditions: Port-site Hernia
Interventions: PROCEDURE: Prophylactic mesh placement|PROCEDURE: Fascial suture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Effects of Plyometrics Versus Conventional Exercises on Speed, Strength, and Injury Prevention in Bowlers.
Status: COMPLETED
Conditions: Sports Injury|Sports Physical Therapy
Interventions: OTHER: PLYOMETRIC EXERCISE PROGRAM|OTHER: CONVENTIONAL EXERCISE PROGRAM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Face Masks to Reduce the Adverse Effects of Diesel Exhaust Inhalation
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: Diesel exhaust exposure with filtered facemask|OTHER: Diesel exhaust exposure with sham mask
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: The Efficacy of TGF for Treating Osteoarthritis of the Knee
Status: UNKNOWN
Conditions: Osteoarthritis, Knee
Interventions: DRUG: TGF|DRUG: TGFP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cabozantinib in Combination With Enfortumab Vedotin for Locally Advanced or Metastatic Urothelial Cancer
Status: RECRUITING
Conditions: Infiltrating Bladder Urothelial Carcinoma With Squamous Differentiation|Locally Advanced Urothelial Carcinoma|Metastatic Urothelial Carcinoma|Unresectable Urothelial Carcinoma
Interventions: DRUG: Cabozantinib S-malate|DRUG: Enfortumab Vedotin|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Pharmacodynamic Effects of VAY736 in Patients With Primary Sjögren's Syndrome
Status: WITHDRAWN
Conditions: Primary Sjögren's Syndrome
Interventions: DRUG: VAY736 lower dose|DRUG: VAY736 higher dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Anti-EGFR Therapy With IMRT Concurrent Chemoradiotherapy in Locally Advanced OPC Resistant to Induction Chemotherapy
Status: UNKNOWN
Conditions: Oropharyngeal Carcinoma
Interventions: DRUG: Anti-EGFR monoclonal antibody
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: rTMS as a Treatment for PPA
Status: COMPLETED
Conditions: Logopenic Variant Primary Progressive Aphasia|Non-Fluent Primary Progressive Aphasia
Interventions: DEVICE: Active rTMS|DEVICE: SHAM rTMS
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Divalproex Sodium in the Treatment of the Cutaneous Manifestations of Scleroderma
Status: WITHDRAWN
Conditions: Scleroderma|Systemic Sclerosis
Interventions: DRUG: Divalproex sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of Safety, Tolerability, Pharmacokinetics/Pharmacodynamics of RP103 Compared to Cystagon® in Patients With Cystinosis
Status: COMPLETED
Conditions: Cystinosis
Interventions: DRUG: Cystagon®|DRUG: RP103
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Light Filters in Intraocular Lenses (IOLs) and Its Influence on Colour and Contrast Vision.
Status: COMPLETED
Conditions: Cataract
Interventions: PROCEDURE: Polylens Y30 intraocular lens|PROCEDURE: Orange Series Model PC 440 Y intraocular lens
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Self-Management of Chronic Low Back Pain: Targeting Patient Activation
Status: COMPLETED
Conditions: Chronic Low-back Pain|Patient Activation
Interventions: BEHAVIORAL: Health Behavior Change Counseling|BEHAVIORAL: Self-management program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Efficacy and Safety of TEL/AML/CTD in Elderly Patients With Essential Hypertension
Status: NOT_YET_RECRUITING
Conditions: Essential Hypertension
Interventions: DRUG: Telmisartan/Amlodipine/Chlorthalidone 40/5/12.5 mg|DRUG: Telmisartan/Amlodipine/Hydrochlorothiazide 40/5/25 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimized Treatment of Peginterferon Alfa 2a in Treatment Experienced Patients With HBV Related Liver Fibrosis
Status: UNKNOWN
Conditions: Hepatitis B|Liver Fibrosis
Interventions: DRUG: Tenofovir Disoproxil Fumarate|DRUG: PEG-Interferon alfa 2a
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Zenith® Fenestrated+ Clinical Study
Status: RECRUITING
Conditions: Aortic Aneurysm, Abdominal|Juxtarenal Aortic Aneurysm|Extent IV Thoracoabdominal|Pararenal Aneurysm
Interventions: DEVICE: Zenith Fenestrated+ Endovascular Graft in combination with the BeGraft Balloon-Expandable FEVAR Bridging Stent Graft System and Unibody2
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ruxolitinib W/ Preop Chemo For Triple Negative Inflammatory Brca
Status: COMPLETED
Conditions: Recurrent Breast Cancer|Metastatic Breast Cancer
Interventions: DRUG: Ruxolitinib|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A First-in-human Trial of GEN3017 in Hodgkin Lymphoma and Non-Hodgkin Lymphoma
Status: RECRUITING
Conditions: Classical Hodgkin Lymphoma|Non-Hodgkin Lymphoma
Interventions: BIOLOGICAL: GEN3017
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Rectal Endoscopic Submucosal Dissection to Endoscopic Mucosal Resection
Status: COMPLETED
Conditions: Colonic Polyps
Interventions: PROCEDURE: Endoscopic Submucosal Dissection|PROCEDURE: Endoscopic Mucosal Resection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 24 Month Open Label Study of the Tolerability and Efficacy of Inotersen in TTR Amyloid Cardiomyopathy Patients
Status: UNKNOWN
Conditions: Amyloidosis
Interventions: DRUG: Inotersen
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Structured Closed Kinetic Chain and Video Based Game Exercise Program in Rotator Cuff Lesion
Status: COMPLETED
Conditions: Rotator Cuff Injuries
Interventions: OTHER: Conventional exercise therapy|OTHER: Closed Chain Exercise Group|OTHER: Video Based Exercise Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RSYR for Fatigue Reduction in Cancer Fatigue Caused by Chemotherapy
Status: ACTIVE_NOT_RECRUITING
Conditions: Cancer-related Problem/Condition
Interventions: DRUG: TCM Formula|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Open Clinical Study, Comparing Non-inferiority of Chronic Plaque Psoriasis
Status: SUSPENDED
Conditions: Plaque Psoriasis
Interventions: DRUG: Each patient will receive a sample of the drug test (tazarotene 0.1%) and a control sample of the drug (calcipotriene 0.005%).
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Bioresorbable Vascular Scaffold in Patients With Myocardial Infarction
Status: COMPLETED
Conditions: ST Elevation Acute Myocardial Infarction
Interventions: DEVICE: Bioresorbable vascular scaffold|DEVICE: Everolimus eluting stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: nCCR for Chemotherapy Related Cognitive Impairment Randomized Study
Status: RECRUITING
Conditions: Chemo-brain|Chemotherapy-Related Cognitive Impairment
Interventions: BEHAVIORAL: Neuroplasticity-based Computerized Cognitive Remediation|BEHAVIORAL: Education Control Condition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Guselkumab for the Treatment of Participants With Crohn's Disease After Surgical Resection
Status: TERMINATED
Conditions: Crohn's Disease
Interventions: DRUG: Guselkumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hepatic Arterial Infusion With Floxuridine and Dexamethasone in Combination With Gemcitabine as Adjuvant Treatment After Resection of Intrahepatic Cholangiocarcinoma
Status: COMPLETED
Conditions: Intrahepatic Cholangiocarcinoma|Peripheral Cholangiocarcinoma|Cholangiolar Carcinoma|Cholangiocellular Carcinoma) (ICC)
Interventions: PROCEDURE: Liver resection and placement of hepatic artery infusion pump|DRUG: FLOXURIDINE|DRUG: DEXAMETHASONE|DRUG: GEMCITABINE
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of tACS for Treatment of Auditory Hallucinations in Refractory Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DEVICE: Transcranial alternating Current Stimulation (tACS)-active|DEVICE: Transcranial Alternating Current Stimulation (tACS)-sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Seltorexant as Adjunctive Therapy to Antidepressants in Adult and Elderly Participants With Major Depressive Disorder With Insomnia Symptoms Who Have Responded Inadequately to Antidepressant and Long-term Safety Extension Treatment With Seltorexant
Status: COMPLETED
Conditions: Depressive Disorder, Major
Interventions: DRUG: Seltorexant|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dose-Ranging Study of Sofosbuvir in Combination With Pegylated Interferon and Ribavirin in Treatment Naïve GT 1 HCV Patients
Status: COMPLETED
Conditions: Hepatitis C
Interventions: DRUG: Sofosbuvir|DRUG: Placebo|DRUG: PEG|DRUG: RBV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Canagliflozin on Liver Inflammation Damage in Type 2 Diabetes Patients With Nonalcoholic Fatty Liver Disease
Status: UNKNOWN
Conditions: Type 2 Diabetes Mellitus With Complication
Interventions: DRUG: Canagliflozin|DRUG: Pioglitazone
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Crisaborole Ointment 2% Skin Biomarker Biopsy Study in Atopic Dermatitis
Status: COMPLETED
Conditions: Dermatitis, Atopic
Interventions: DRUG: Crisaborole ointment 2% BID|DRUG: Placebo ointment (vehicle)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Early High-Titre Convalescent Plasma in Clinically Vulnerable Individuals With Mild COVID-19
Status: RECRUITING
Conditions: COVID-19
Interventions: BIOLOGICAL: Current standard of care and COVID-19 convalescent and vaccinated plasma|OTHER: Current standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Relationship Between Scar Formation and ESD Depth in Therapy for Gastric Carcinoma
Status: RECRUITING
Conditions: Early Gastric Cancer|Endoscopic Submucosal Dissection
Interventions: PROCEDURE: ESD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Study Evaluating Efficacy and Safety of Multiple Treatment Combinations in Patients With Locally Advanced Squamous Cell Carcinoma of the Head and Neck (Morpheus-Head and Neck Cancer)
Status: COMPLETED
Conditions: Squamous Cell Carcinoma of the Head and Neck
Interventions: DRUG: Atezolizumab|DRUG: Tiragolumab|DRUG: Carboplatin|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Case Series Evaluating Skin Wellness System
Status: COMPLETED
Conditions: Moisture-associated Dermatitis|Fungal Infection in Perineal Area
Interventions: DRUG: Kendall Body Wash & Shampoo; Moisture Barrier Cream; 2-in-1 Cleanser; Antifungal Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CANVAS - CANagliflozin cardioVascular Assessment Study
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Cardiovascular Diseases|Risk Factors
Interventions: DRUG: Placebo|DRUG: Canagliflozin (JNJ-28431754) 100 mg|DRUG: Canagliflozin (JNJ-28431754) 300 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety of Indacaterol in Patients (≥ 12 Years) With Moderate to Severe Persistent Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Indacaterol 300 μg|DRUG: Salmeterol 50 μg|DRUG: Placebo to indacaterol|DRUG: Placebo to salmeterol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cost Analysis for Endoscopic Retrograde Cholangiopancreatography (ERCP)
Status: WITHDRAWN
Conditions: Biliary Obstruction
Interventions: PROCEDURE: Endoscopist informed of cost per procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: OTHER
Clinical trial: Vitamin E in Aging Persons With Down Syndrome
Status: UNKNOWN
Conditions: Down Syndrome|Alzheimer Disease
Interventions: DRUG: Vitamin E|DRUG: multivitamin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of a Combination of Nootropic Ingredients on Cognition in Healthy Young Volunteers
Status: COMPLETED
Conditions: Biomedical Enhancement
Interventions: DIETARY_SUPPLEMENT: CAF+|DIETARY_SUPPLEMENT: Caffeine-alone|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of Intraoperative and Postoperative Outcomes of Bartholin Gland Marsupialisation Versus Cystectomy
Status: COMPLETED
Conditions: Bartholin Abscess
Interventions: OTHER: Excision|OTHER: Marsupialization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: RCT Evaluating Standardized Counseling on Early Discontinuation for Irregular Bleeding in Nexplanon Users
Status: RECRUITING
Conditions: Birth Control|Contraception|Contraceptive Usage|Family Planning
Interventions: OTHER: Additional Standardized Counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Topical Administration of 0.15% Ganciclovir Gel for CMV Anterior Uveitis / Endotheliitis
Status: COMPLETED
Conditions: Cytomegalovirus Anterior Segment Infection|Anterior Uveitis|Endotheliitis
Interventions: DRUG: Ganciclovir
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Viral Load Determination and Biomarkers of High Risk Human Papillomavirus (HPV) - Types in HIV-positive Men
Status: UNKNOWN
Conditions: HIV Infections|Papillomavirus Infections|Anal Intraepithelial Neoplasia
Interventions: BEHAVIORAL: Smear and biopsy testing for HPV-types and viral load
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Dietary Interventions on the Aging Brain
Status: UNKNOWN
Conditions: Healthy
Interventions: BEHAVIORAL: Caloric restriction|DIETARY_SUPPLEMENT: Omega-3 (fish oil capsules)|DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: Resveratrol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Phase 2 Study to Evaluate the Safety and Efficacy of Pitolisant in Patients With Prader-Willi Syndrome, Followed by an Open Label Extension
Status: ACTIVE_NOT_RECRUITING
Conditions: Prader-Willi Syndrome
Interventions: DRUG: Pitolisant oral tablets|DRUG: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Injectable Platelets Rich Fibrin Versus Hyaluronic Acid for Alveolar Ridge Preservation
Status: COMPLETED
Conditions: Alveolar Ridge Enlargement
Interventions: PROCEDURE: Alveolar ridge augmentation with injectable platelets rich fibrin|PROCEDURE: Alveolar ridge augmentation with hyaluronic acid|PROCEDURE: Alveolar ridge augmentation with xenograft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: PK/PD Study of Gan & Lee Insulin Aspart Injection vs. US & EU NovoLog®/NovoRapid® in Healthy Males
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: DRUG: Gan & Lee Insulin Aspart
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Research Study to See How Well the New Weekly Medicine IcoSema, Which is a Combination of Insulin Icodec and Semaglutide, Controls Blood Sugar Level in People With Type 2 Diabetes Compared to Insulin Glargine Taken Daily With Insulin Aspart (COMBINE 3)
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: IcoSema|DRUG: Insulin glargine|DRUG: insulin aspart
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Standardized Natural Psilocybin-assisted Psychotherapy for Tapering of Opioid Medication
Status: NOT_YET_RECRUITING
Conditions: Opioid Dependence|Chronic Pain
Interventions: DRUG: Psilocybin-assisted Psychotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Safety, and Tolerability of Higher Doses Estrogen Therapy in Women With Premature Ovarian Insufficiency
Status: ACTIVE_NOT_RECRUITING
Conditions: Primary Ovarian Insufficiency
Interventions: DRUG: Transdermal estradiol gel 0.1% 1.5mg/ day|DRUG: Transdermal estradiol gel 0.1% 2.0mg/ day
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Impact of Renal Denervation in Patients With Coronary Microvascular Dysfunction: Study Design and Rationale
Status: NOT_YET_RECRUITING
Conditions: Coronary Microvascular Dysfunction|Resistant Hypertension|Hypertensive Heart Disease
Interventions: DIAGNOSTIC_TEST: Invasive Physiological Assessment of Coronary Circulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Drug-drug Interaction of Empagliflozin (BI 10773) and Simvastatin
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BI 10773|DRUG: simvastatin|DRUG: simvastatin|DRUG: BI 10773
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Visilizumab for the Prevention of Graft-versus-Host Disease After Allogeneic Hematopoietic Cell Transplantation
Status: TERMINATED
Conditions: Graft Versus Host Disease
Interventions: DRUG: Visilizumab|DRUG: Tacrolimus|DRUG: Methotrexate|DRUG: Antithymocyte globulin (ATG)|DRUG: Tacrolimus|DRUG: Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: THALES - Acute STroke or Transient IscHaemic Attack Treated With TicAgreLor and ASA for PrEvention of Stroke and Death
Status: COMPLETED
Conditions: Acute Ischaemic Stroke|Transient Ischaemic Attack
Interventions: DRUG: Ticagrelor|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigation of the Clinical Safety and Efficacy of Long-term Treatment With Fycompa Tablets in Adult Epilepsy Patients With Partial-onset Seizures (With or Without Secondary Generalized Seizures) or Primary Generalized Tonic-clonic Seizures
Status: COMPLETED
Conditions: Partial Seizures (With or Without Secondary Generalized Seizures)|Primary Generalized Tonic-clonic Seizures
Interventions: DRUG: Fycompa
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Efficacy of Local Anesthetics to Reduce Shoulder Pain Post-Steroid Injections
Status: TERMINATED
Conditions: Shoulder Pain
Interventions: DRUG: lidocaine|DRUG: ethyl chloride|DRUG: Kenalog
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Digoxin Evaluation in Chronic Heart Failure: Investigational Study In Outpatients in the Netherlands
Status: ACTIVE_NOT_RECRUITING
Conditions: Heart Failure
Interventions: DRUG: Digoxin|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: E7389 in Treating Patients With Recurrent or Progressive Stage IIIB or Stage IV Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Recurrent Non-small Cell Lung Cancer|Stage IIIB Non-small Cell Lung Cancer|Stage IV Non-small Cell Lung Cancer
Interventions: DRUG: eribulin mesylate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improving Follow-Up Adherence in a Primary Eye Care Setting
Status: COMPLETED
Conditions: Eye Diseases
Interventions: BEHAVIORAL: Automated Telephone System|BEHAVIORAL: Personalized Telephone Call|BEHAVIORAL: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: NEOadjuvant Abemaciclib and GIredestrant triaL in Patients With ER-positive, HER2-negative Early Breast Cancer
Status: NOT_YET_RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Abemaciclib 150 MG + Giredestrant 30 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Digital Assessment Routing Tool (DART): Pilot Study
Status: COMPLETED
Conditions: Musculoskeletal Diseases or Conditions
Interventions: OTHER: Digital Assessment Routing Tool [DART]|OTHER: Physiotherapy-led remote triage (usual care)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Study to Evaluate the Safety and Efficacy of 2ccPA in Patients With Symptomatic Knee Osteoarthritis
Status: ACTIVE_NOT_RECRUITING
Conditions: Osteoarthritis, Knee
Interventions: DRUG: 2ccPA|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Sorafenib Plus Pravastatin to Treat Advanced Hepatocarcinoma
Status: COMPLETED
Conditions: Advanced Hepatocarcinoma
Interventions: DRUG: Pravastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) for Food Craving in Obese Individuals.
Status: UNKNOWN
Conditions: Obesity|Craving
Interventions: DEVICE: Active-taVNS|DEVICE: Sham-taVNS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Gemigliptin Versus Sitagliptin or Glimepiride With Metformin on Glucose Variability(MAGE, Glucose SD) Patients With Type 2 DM(STABLE Study)
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Gemigliptin + Metformin / Sitagliptin + Metformin / Glimepiride + Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of 4 Diets in the Management of Overweight Patients With Vascular Disease
Status: TERMINATED
Conditions: Obesity|Cardiovascular Disease|Metabolic Syndrome
Interventions: OTHER: Low glycemic load diet|OTHER: Canada Food Guide Diet|OTHER: Low glycemic index diet|OTHER: Low carbohydrate diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Kegal Exercises With and Without Postural Correction on Postpartum Pelvic Organ Prolapse in Primiparous Women
Status: RECRUITING
Conditions: Pelvic Organ Prolapse
Interventions: OTHER: Kegal exercises with postural correction|OTHER: Kegal exercises without postural correction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Nivolumab in Combination w Radium-223 in Men w Metastatic Castration Resistant Prostate Cancer
Status: RECRUITING
Conditions: Metastatic Castration-resistant Prostate Cancer
Interventions: DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of nrTMS Therapy on the Progress of Neurorehabilitation
Status: UNKNOWN
Conditions: Transcranial Magnetic Stimulation, Repetitive
Interventions: DEVICE: navigated repetitive transcranial magnetic stimulation|PROCEDURE: physical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I Clinical Trial of BAT1306 and BAT8001 Injection in Patients With Solid Tumor
Status: UNKNOWN
Conditions: Solid Tumor
Interventions: BIOLOGICAL: BAT1306 and BAT8001 2.4mg/kg|BIOLOGICAL: BAT1306 and BAT8001 3.6mg/kg
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Investigational Drug Study in the Treatment of Primary Dysmenorrhea (0663-064)
Status: COMPLETED
Conditions: Dysmenorrhea
Interventions: DRUG: etoricoxib (MK0663)|DRUG: Comparator: placebo (unspecified)|DRUG: Comparator: naproxen sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Imatinib Mesylate With or Without Radiation Therapy in Treating Young Patients With Newly Diagnosed or Recurrent Glioma
Status: TERMINATED
Conditions: Brain and Central Nervous System Tumors
Interventions: DRUG: imatinib mesylate|RADIATION: local irradiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Atacicept in IgA Nephropathy
Status: TERMINATED
Conditions: IgA Nephropathy
Interventions: DRUG: Placebo|DRUG: Atacicept 25 mg|DRUG: Atacicept 75 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Atazanavir or Boosted Atazanavir Substitution for Ritonavir Boosted PI in Patients With Hyperlipidemia
Status: COMPLETED
Conditions: Hyperlipidemia|HIV Infections
Interventions: DRUG: Atazanavir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, and Efficacy of Encaleret in Participants With Autosomal Dominant Hypocalcemia (ADH) Type 1
Status: COMPLETED
Conditions: Autosomal Dominant Hypocalcemia (ADH)
Interventions: DRUG: Encaleret
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Studying Amphetamine Withdrawal in Humans
Status: COMPLETED
Conditions: Methamphetamine Dependence
Interventions: DRUG: Dextroamphetamine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Key Techniques of Prevention and Treatment of Osteoporotic Refracture
Status: NOT_YET_RECRUITING
Conditions: Osteoporotic Fractures
Interventions: DRUG: Denosumab|DRUG: Teriparatide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Gas Supply, Demand and Middle Ear Gas Balance -- Fly/Dive Simulation
Status: COMPLETED
Conditions: Middle-ear Barotrauma
Interventions: OTHER: flight/diving simulation|OTHER: ET function testing at ambient pressure|OTHER: nasal video-endoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Innovative Cognitive and Behavioral Psychotherapy for Cocaine Use Disorder
Status: RECRUITING
Conditions: Cocaine Use Disorder
Interventions: BEHAVIORAL: Virtual Reality Cue Exposure (VRCE) Therapy for Cocaine Craving - 2 weeks|OTHER: Memory Focused Cognitive Therapy (MFCT) - 1 week|BEHAVIORAL: Pictures-based Cue Exposure (PCE) Therapy for Cocaine Craving - 3 weeks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Laser Acupuncture in Egyptian Systemic Lupus Females With Insulin Resistance
Status: RECRUITING
Conditions: Systemic Lupus Erythematosus|PreDiabetes
Interventions: DEVICE: active laser|DEVICE: sham laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ziprasidone for Severe Conduct and Other Disruptive Behavior Disorders
Status: COMPLETED
Conditions: Conduct Disorder|Oppositional Defiant Disorder
Interventions: DRUG: Ziprasidone Hydrochloride|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Diet Intervention for Crohn's Disease Patient
Status: COMPLETED
Conditions: Crohn Disease
Interventions: BEHAVIORAL: Diet Counseling|OTHER: CD LFD|BEHAVIORAL: Dyadic Psychological Support (DPS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Efficacy Study of the Evoke™ SCS System With Feedback vs. Conventional Stimulation
Status: COMPLETED
Conditions: Chronic Pain|Back Pain|Pain
Interventions: DEVICE: Evoke Spinal Cord Stimulator (SCS) System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dialectical Behavioral Therapy As A Therapeutic Tool In Patients With Binge Eating Disorder
Status: ACTIVE_NOT_RECRUITING
Conditions: Binge Eating Disorder
Interventions: BEHAVIORAL: DBT|DRUG: TAU|DIAGNOSTIC_TEST: Plasma Ghrelin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chest Mobility Exercises Versus Proprioceptive Neuromuscular Facilitation in Patients With COPD
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease Moderate
Interventions: OTHER: Chest mobility exercises|OTHER: proprioceptive neuromuscular facilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Bandage Contact Lenses Versus Eye Patching of Müller's Muscle-conjunctival Resection
Status: COMPLETED
Conditions: Eyelid Diseases
Interventions: PROCEDURE: bandage contact lens
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Bendamustine, Gemcitabine, Rituximab, Nivolumab (BeGeRN) in Patients With r/r DLBCL
Status: COMPLETED
Conditions: Diffuse Large B Cell Lymphoma
Interventions: DRUG: Bendamustine hydrochloride|DRUG: Gemcitabine 500 mg|DRUG: Gemcitabine 700 mg|DRUG: Gemcitabine 1000 mg|DRUG: Nivolumab|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial to Investigate the Efficacy and Safety of Tongkat Ali Maca Plus
Status: COMPLETED
Conditions: Erectile Dysfunction
Interventions: DIETARY_SUPPLEMENT: Tongkat Ali Maca Plus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT