pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: The Effect of Desloratadine and Levocetirizine on Nasal Obstruction (Study P03609)
Status: COMPLETED
Conditions: Allergic Rhinitis
Interventions: DRUG: desloratadine|DRUG: levocetirizine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Effect of Ivacaftor on Lung Clearance Index in Subjects With Cystic Fibrosis and the G551D Mutation
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: Ivacaftor|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Daratumumab With the Addition of Recombinant Human Hyaluronidase (rHuPH20) for the Treatment of Participants With Relapsed or Refractory Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Daratumumab Subcutaneous (SC) Administration|DRUG: Recombinant Human Hyaluronidase [rHuPH20]) SC Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pembrolizumab in Combination With Salvage Chemotherapy for First-relapsed or Refractory Classical Hodgkin Lymphoma
Status: RECRUITING
Conditions: Classical Hodgkin Lymphoma
Interventions: DRUG: Pembrolizumab plus Chemotherapy (ICE or DHAP)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical and Radiological Outcomes: Two-level Cervical ProDisc-C Vivo Versus Hybrid Construct.
Status: NOT_YET_RECRUITING
Conditions: Cervical Disc Disease
Interventions: PROCEDURE: Two level Prodisc-C vivo|PROCEDURE: Hybrid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Forteo (Teriparatide) in Posterolateral Lumbar Spine Fusion
Status: COMPLETED
Conditions: Lumbar Spondylosis|Lumbar Spondylolisthesis|Adult Degenerative Lumbar Scoliosis
Interventions: BIOLOGICAL: teriparatide|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Find Out Whether Participants With a History of Stuffy Nose Due to Allergic Reactions in the Nose Would Intend to Buy Drug Phenylephrine Hydrochloride Extended Release Tablets After Receiving it Once in This Study
Status: COMPLETED
Conditions: Nasal Congestion Due to Allergic Rhinitis
Interventions: DRUG: Phenylephrine HCl (Sinus Comfort, BAY112476)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Prospective Evaluation of High Intensity Focused Ultrasound (HIFU) in the Treatment of Benign Thyroid Nodules
Status: COMPLETED
Conditions: Benign Thyroid Nodules
Interventions: DEVICE: Echopulse
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Losmapimod in Chronic Obstructive Pulmonary Disease Patients Stratified by Fibrinogen.
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Losmapimod|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Toronto Bedside Swallowing Screening Test (TOR-BSST) - A Bedside Swallowing Screening for Stroke Patients
Status: COMPLETED
Conditions: Cerebrovascular Accident|Deglutition Disorders
Interventions: DEVICE: Toronto Bedside Swallowing Screening Test (TOR-BSST)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of Onapristone ER Alone Or In Combination With Anastrozole in Gynecologic Cancers That Respond to Progesterone
Status: ACTIVE_NOT_RECRUITING
Conditions: Granulosa Cell Ovarian Cancer|Low Grade Serous Ovarian/ Primary Peritoneal Cancer|Endometrioid Endometrial Cancer
Interventions: DRUG: Onapristone ER|DRUG: Onapristone ER + Anastrozole
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Healthy Mothers: an Intervention to Support Perinatal Women Living With HIV in Kenya
Status: COMPLETED
Conditions: Mental Health Issue|Hiv|Breastfeeding, Exclusive
Interventions: BEHAVIORAL: personalized lactation support
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Clinical Study to Evaluate the Maximum Tolerated Dose of BAY1000394 Given in a 3 Days on / 4 Days Off Schedule in Subjects With Advanced Malignancies
Status: COMPLETED
Conditions: Neoplasms
Interventions: DRUG: Roniciclib (BAY1000394)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multi-hospital Electronic Decision Support for Drug-associated Acute Kidney Injury
Status: ENROLLING_BY_INVITATION
Conditions: Acute Kidney Injury
Interventions: OTHER: Level A|OTHER: Level B|OTHER: Passive Alert
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Tagraxofusp and Low-Intensity Chemotherapy for CD123-Positive Relapsed or Refractory AML
Status: NOT_YET_RECRUITING
Conditions: Refractory Acute Myeloid Leukemia|Relapsed Acute Myeloid Leukemia
Interventions: DRUG: Tagraxofusp|DRUG: Cladribine (CLAD)|DRUG: Cytarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rehabilitation for Total Knee Replacement: a Novel Biofeedback System Versus Conventional Home-based Rehabilitation
Status: COMPLETED
Conditions: Knee Osteoarthritis|Arthropathy of Knee
Interventions: DEVICE: Home-based rehabilitation with a digital biofeedback system|OTHER: Conventional Home-based rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Iron/Folic Acid vs Folic Acid Supplements During Pregnancy on Maternal and Child Health
Status: COMPLETED
Conditions: Iron Deficiency|Iron Deficiency Anemia
Interventions: DIETARY_SUPPLEMENT: Ferrous Sulfate + folic acid|DIETARY_SUPPLEMENT: Folic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: RESET-Myositis: An Open-Label Study to Evaluate the Safety and Efficacy of CABA-201 in Subjects With Active Idiopathic Inflammatory Myopathy
Status: RECRUITING
Conditions: Idiopathic Inflammatory Myopathy|Dermatomyositis|Anti-Synthetase Syndrome|Immune-Mediated Necrotizing Myopathy
Interventions: BIOLOGICAL: CABA-201 following preconditioning with fludarabine and cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity, Safety and Tolerability of a Plant-Derived Seasonal VLP Quadrivalent Influenza Vaccine in the Elderly Population
Status: COMPLETED
Conditions: Virus Diseases|RNA Virus Infections|Respiratory Tract Diseases|Respiratory Tract Infections
Interventions: BIOLOGICAL: Non-adjuvanted low dose of quadrivalent VLP vaccine|BIOLOGICAL: Non-adjuvanted medium dose of quadrivalent VLP vaccine|BIOLOGICAL: Non-adjuvanted high dose of quadrivalent VLP vaccine|BIOLOGICAL: Adjuvanted low dose of quadrivalent VLP vaccine|BIOLOGICAL: Adjuvanted high dose of quadrivalent VLP vaccine|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Inferior Mesenteric Artery Preservation in Laparoscopic Colorectal Resection for Diverticular Disease.
Status: COMPLETED
Conditions: Colonic Diverticuar Disease|Defecatory Functions|Fecal Incontinence|Constipation
Interventions: PROCEDURE: IMA preserving|PROCEDURE: IMA sectioning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety, Pharmacokinetics and Efficacy of PP405 in Adults With AGA
Status: RECRUITING
Conditions: Androgenetic Alopecia
Interventions: DRUG: PP405 0.05% Topical Gel|DRUG: PP405 Topical Vehicle Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Lidocaine Pertubation as a Treatment for Unexplained Infertility
Status: UNKNOWN
Conditions: Unexplained Infertility
Interventions: DRUG: Isifera+|DRUG: Buffer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Pivotal Trial to Establish the Efficacy and Long-term Safety of the Parachute Implant System
Status: TERMINATED
Conditions: Congestive Heart Failure|Left Ventricular (LV) Systolic Dysfunction
Interventions: DEVICE: CardioKinetix Parachute Implant and All Appropriate Medical Therapy (AAMT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Incidence and Severity of Diarrhea in Patients With HER2 Positive Breast Cancer Treated With Trastuzumab and Neratinib
Status: COMPLETED
Conditions: HER2-positive Breast Cancer|Breast Adenocarcinoma|Stage II Breast Cancer AJCC v6 and v7|Stage IIA Breast Cancer AJCC v6 and v7|Stage IIB Breast Cancer AJCC v6 and v7|Stage III Breast Cancer AJCC v7|Stage IIIA Breast Cancer AJCC v7|Stage IIIB Breast Cancer AJCC v7|Stage IIIC Breast Cancer AJCC v7
Interventions: DRUG: Neratinib|BIOLOGICAL: Trastuzumab|DRUG: Loperamide|DRUG: Diphenoxylate Hydrochloride/Atropine Sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: QH103 Cell Injection for the Treatment of Relapsed/Refractory B-cell Acute Lymphoblastic Leukemia
Status: RECRUITING
Conditions: B-cell Acute Lymphoblastic Leukemia
Interventions: BIOLOGICAL: QH103 Cell Injection|DRUG: Fludarabine|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Antibiotic Based Irrigation for Ureteroscopic Treatment of Urolithiasis
Status: NOT_YET_RECRUITING
Conditions: Urinary Tract Infections|Sepsis
Interventions: DRUG: Gentamicin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Bioequivalence Study of the Fixed Dose Combination of 5 mg Saxagliptin/1000 mg Metformin XR (Manufactured in Mt Vernon, IN) Relative to 5 mg of Onglyza and 2 × 500 mg Glucophage XR
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: DRUG: saxagliptin|DRUG: Glucophage XR|DRUG: saxagliptin + metformin XR (FDC tablet)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: The Real Life Topical Field Treatment of Actinic Keratosis Study
Status: COMPLETED
Conditions: Actinic Keratosis
Interventions: DRUG: Ingenol mebutate|DRUG: 5-fluorouracil|DRUG: Imiquimod|DRUG: Diclofenac
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Clinical Trial to Compare Efficacy and Tolerability of Atorvastatin in Addition to Endocrine Treatment With Focus on Mechanisms of Resistance to Endocrine Treatment (Fulvestrant/Aromatase Inhibitors) in Patients With Advanced Breast Cancer
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: DRUG: Letrozole|DRUG: Letrozole and atorvastatin|DRUG: Fulvestrant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dermal Tolerability of Dapsone Gel in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: dapsone gel|DRUG: dapsone gel vehicle|DRUG: sodium lauryl sulfate|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Efficacy of Early Implantation of a Percutaneous Left Ventricular Assist Devices in Acute Coronary Syndrome Complicated by Cardiogenic Shock Compared to Conventional Therapy: a Prospective, Multicenter, Randomized, Controlled and Open-label Clinical Trial
Status: RECRUITING
Conditions: Cardiogenic Shock
Interventions: DEVICE: IMPELLA CP|OTHER: Conventional therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Respiratory Muscle Function in Untreated X-Linked Myotubular Myopathy (XLMTM)
Status: COMPLETED
Conditions: X-linked Myotubular Myopathy
Interventions: OTHER: History and physical|OTHER: Tidal breathing|OTHER: Maximal respiratory pressures|OTHER: Peak cough flow|OTHER: Pediatric Evaluation of Disability Inventory|OTHER: PedsQL Multidimensional Fatigue Scale|OTHER: Review of ventilation requirements
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effectiveness of BenZalkonium Chloride Gel as Vaginal Contraceptive: a Multicentric Randomized Controlled Trial
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: a novel Benzalkonium Chloride (BZK) contraceptive gel|DRUG: LELEMI® contraceptive gel containing 50mg nonoxynol-9
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Role of the Microparticles and of Tissue Factor in the Pro-thrombotic Phenotype and the Thromboembolic Complications During the Acute Lymphoblastic Leukemia in Children.
Status: COMPLETED
Conditions: Acute Lymphoblastic Leukemia
Interventions: OTHER: Blood sample
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Azelastine Allergen Chamber - Onset of Action Study
Status: COMPLETED
Conditions: Seasonal Allergic Rhinitis
Interventions: DRUG: Treatment A: Azelastine hydrochloride 0.15% nasal spray (Azelair)|DRUG: Treatment B: Placebo (Azelastine 0.15% vehicle) nasal spray|DRUG: Treatment C: Ryaltris (Active Control) - mometasone furoate monohydrate and olopatadine hydrochloride nasal spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Three Therapy-Based Interventions for Preventing Depression in Adolescents
Status: COMPLETED
Conditions: Depression
Interventions: BEHAVIORAL: IPT-AST|OTHER: Enhanced IPT-AST|OTHER: School counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: AL-54478 Proof of Concept Study
Status: COMPLETED
Conditions: Open-angle Glaucoma (OAG)|Ocular Hypertension (OHT)
Interventions: DRUG: AL-54478 0.005%|DRUG: Latanoprost 0.005%|DRUG: AL-54478 Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sub-Dissociative Ketamine and Fentanyl to Treat Moderate to Severe Pain
Status: TERMINATED
Conditions: Pain, Acute
Interventions: DRUG: Fentanyl|COMBINATION_PRODUCT: Fentanyl and Ketamine|DRUG: Ketamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: CAELYX Versus Paclitaxel HCl in Patients With Epithelial Ovarian Carcinoma Following Failure of First-Line, Platinum-Based Chemotherapy
Status: TERMINATED
Conditions: Ovarian Neoplasms
Interventions: DRUG: CAELYX|DRUG: Paclitaxel HCl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Liver Transplant Does it Affect the Brain
Status: COMPLETED
Conditions: Brain Damage|Postoperative Cognitive Dysfunction|Neuron Specific Enolase|Glial Fibrillary Acidic Protein
Interventions: DIAGNOSTIC_TEST: Mini Mental Test (MMT), S-100 beta, Neuron specific enolase and Glial fibrillary acidic protein
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: BI 655066 / ABBV-066 (Risankizumab) in Moderate to Severe Plaque Psoriasis With Randomized Withdrawal and Re-treatment
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: Risankizumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: First-line Apatinib Combined With Tislelizumab and Chemotherapy for Advanced GC
Status: COMPLETED
Conditions: Advanced Gastric Adenocarcinoma
Interventions: DRUG: Apatinib Combined With Tislelizumab and Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Direct Versus Indirect Pick up of the Locator Retentive Caps:(Within-patient Study)
Status: COMPLETED
Conditions: Prosthesis Durability
Interventions: PROCEDURE: dental implants in the mandible|DEVICE: locator attachment and overdenture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence & Food Effect Study in Patients With Solid Tumor or Hematologic Malignancies
Status: COMPLETED
Conditions: Hematological Neoplasms|Non-Hodgkin's Lymphoma|Hodgkin's Lymphoma|Lymphoma|Multiple Myeloma|Acute Myeloid Leukemia|Leukemia|Myelodysplastic Syndromes|Neoplasms|Melanoma|Breast Cancer|Metastatic Breast Cancer|Non-Small Cell Lung Cancer|Small Cell Lung Cancer|Renal Cell Carcinoma|Glioblastoma Multiforme|Osteosarcoma|Sarcoma|Thyroid Cancer|Genitourinary
Interventions: DRUG: CC-486|DRUG: Vidaza
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Vitamin A Supplementation on Cytokine Profile in Obesity
Status: UNKNOWN
Conditions: Obesity
Interventions: DIETARY_SUPPLEMENT: Vitamin A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acceptability of Mobile Applications (Apps) to Enhance Smoking Cessation in a Clinical Tobacco Treatment Program - A Pilot Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Smoking Cessation|Tobacco
Interventions: DEVICE: smartphone applications|DEVICE: smartphone applications
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: NEwborn Infant of a Mother With Obesity - Fecal Microbiome Transplantation, RCT
Status: NOT_YET_RECRUITING
Conditions: Fecal Microbiota Transplantation|Cesarean Section|Overweight and Obesity
Interventions: DIETARY_SUPPLEMENT: Fecal transplant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Paclitaxel Albumin-Stabilized Nanoparticle Formulation in Treating Patients With Recurrent or Persistent Ovarian Epithelial Cancer, Fallopian Tube Cancer, or Primary Peritoneal Cancer
Status: COMPLETED
Conditions: Fallopian Tube Carcinoma|Primary Peritoneal Carcinoma|Recurrent Ovarian Carcinoma
Interventions: DRUG: Paclitaxel Albumin-Stabilized Nanoparticle Formulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Inflammatory and Cerebrospinal Biochemical Markers in Blood After Trimix Diving
Status: COMPLETED
Conditions: Diving Medicine|Inflammation|Central Nervous System Injury
Interventions: OTHER: Exposure to oxygen partial pressure of 130 kPa|OTHER: Exposure to ambient pressure of maximum 11 ATA
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Metoclopramide for Post-Traumatic Headache. A Pilot Study
Status: COMPLETED
Conditions: Post-Traumatic Headache
Interventions: DRUG: Metoclopramide|DRUG: Diphenhydramine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stem Cell Educator Therapy Treat the Viral Inflammation in COVID-19
Status: UNKNOWN
Conditions: Severe Acute Respiratory Syndrome (SARS) Pneumonia
Interventions: COMBINATION_PRODUCT: Stem Cell Educator-Treated Mononuclear Cells Apheresis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Vacuum Erection Device in Improving Recovery of Erectile Function in Patients With Prostate Cancer Undergoing Surgery
Status: COMPLETED
Conditions: Male Erectile Disorder|Prostate Cancer|Sexual Dysfunction
Interventions: OTHER: Sexual Health Inventory for Men (SHIM) questionnaire administration|PROCEDURE: management of therapy complications|PROCEDURE: Daily vacuum therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Hypo-Combi Trial: Hypofractionated EBRT Plus HDR-BT Boost for Prostate Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Adenocarcinoma|Radiation Toxicity
Interventions: RADIATION: External beam radiation therapy, High-dose-rate brachytherapy|DRUG: Goserelin 10.8 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Fast-rotation Coronary CT in Patients Undergoing Aortic Stenosis Workup
Status: RECRUITING
Conditions: Coronary Stenosis|Aortic Valve Stenosis|Cardiovascular Diseases
Interventions: DIAGNOSTIC_TEST: Aortic CTA, .23s|DIAGNOSTIC_TEST: Aortic CTA, .28s
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Bone Marrow Transplantation in Treating Patients With Severe Aplastic Anemia or Rejection of Previous Bone Marrow Transplant
Status: TERMINATED
Conditions: Chronic Myeloproliferative Disorders|Graft Versus Host Disease|Leukemia|Lymphoma|Multiple Myeloma and Plasma Cell Neoplasm|Myelodysplastic Syndromes
Interventions: BIOLOGICAL: anti-thymocyte globulin|BIOLOGICAL: filgrastim|BIOLOGICAL: muromonab-CD3|DRUG: cyclophosphamide|DRUG: cyclosporine|DRUG: methylprednisolone|PROCEDURE: allogeneic bone marrow transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of SHR3824 as Monotherapy in Subjects With Type 2 Diabetes
Status: UNKNOWN
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: SHR3824|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of SC-0191 in Subjects With Metastatic Colorectal Cancer
Status: NOT_YET_RECRUITING
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: SC0191|DRUG: SC0191 + Bevacizumab|DRUG: SC0191 + 5-FU/LV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: MegaNatural BP® GSE on Blood Pressure and Cardiometabolic Risk Factors
Status: RECRUITING
Conditions: Hypertension|Pre Diabetes
Interventions: DRUG: MegaNatural-BP SR 150Mg Tablet|OTHER: Placebo Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Tocilizumab for the Treatment of Cytokine Release Syndrome in Patients With COVID-19 (SARS-CoV-2 Infection)
Status: WITHDRAWN
Conditions: Cerebrovascular Accident|Chronic Obstructive Pulmonary Disease|Chronic Renal Failure|Coronary Artery Disease|Diabetes Mellitus|Malignant Neoplasm|SARS Coronavirus 2 Infection
Interventions: OTHER: Best Practice|BIOLOGICAL: Tocilizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Oral Care in the Neuroscience ICU
Status: COMPLETED
Conditions: Ventilator Associated Pneumonia|Oral Hygiene
Interventions: PROCEDURE: Standard Oral Care|PROCEDURE: Comprehensive Oral Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Closed Intravenous Catheter System on Catheter Success, Length of Stay and Complications
Status: COMPLETED
Conditions: Catheter Complications|Catheter Leakage
Interventions: DEVICE: closed IV catheter system (BD Nexiva™)|DEVICE: open IV catheter (BD Insyte™ Autoguard™)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Steroids vs Placebo in Treatment of Tuberculous Lymphadenitis
Status: COMPLETED
Conditions: Tuberculous Lymphadenitis, Cervical
Interventions: DRUG: Ferrous sulfate|DRUG: Deltacortril
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Postoperative Pain Management in Rhinoplasty
Status: ACTIVE_NOT_RECRUITING
Conditions: Pain, Postoperative
Interventions: DRUG: Norco 5Mg-325Mg Tablet|DRUG: Tylenol 325Mg Caplet|DRUG: Ibuprofen 200 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The HOPE Study: Characterizing Patients With Hepatitis B and C
Status: RECRUITING
Conditions: Hepatitis B， Chronic|Hepatitis C
Interventions: OTHER: Blood draws|DRUG: Tenofovir Alafenamide|OTHER: Knowledge Index Questionnaire|OTHER: Liver transient elastography (FibroScan)|PROCEDURE: Liver Biopsy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: To Determine the Maximum Tolerated Dose of Oral CEP-37440 in Patients With Advanced or Metastatic Solid Tumors
Status: COMPLETED
Conditions: Solid Tumors
Interventions: DRUG: CEP-37440
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Safety and Efficacy of Nivolumab and Bendamustine (NB) in Patients With Relapsed/Refractory Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Hodgkin's Lymphoma
Interventions: DRUG: Nivolumab|DRUG: Bendamustine Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trientine Tetrahydrochloride (TETA 4HCL) for the Treatment of Wilson's Disease
Status: COMPLETED
Conditions: Wilson Disease
Interventions: DRUG: Penicillamine (D1-W12)|DRUG: TETA 4HCL (W12-60)|DRUG: Penicillamine (W12-W60)|DRUG: TETA 4HCL (60-<W108)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SMARThealth Pregnancy: Feasibility & Acceptability of a Complex Intervention for High-risk Pregnant Women in Rural India.
Status: COMPLETED
Conditions: Pre-Eclampsia|Gestational Diabetes|Anemia
Interventions: OTHER: SMARThealth Pregnancy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Head-dOwn Position for ischEmic Stroke With Middle Cerebral Artery (HOPES)
Status: TERMINATED
Conditions: Ischemic Stroke
Interventions: OTHER: head-down position treatment|OTHER: Conventional Rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Fampridine-SR Tablets in Multiple Sclerosis Patients
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DRUG: Fampridine-SR|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PET Scan and CT Scan in Evaluating Response in Patients Undergoing Radiofrequency Ablation for Lung Metastases
Status: COMPLETED
Conditions: Metastatic Cancer|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: PROCEDURE: computed tomography|PROCEDURE: positron emission tomography|PROCEDURE: radiofrequency ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Progression of Striatal and Extrastriatal Degeneration in PD and PSP Patients
Status: COMPLETED
Conditions: Parkinson Disease (PD)|Paralysis; Supranuclear
Interventions: DIAGNOSTIC_TEST: 3D gait analysis|DIAGNOSTIC_TEST: rsfMRI|DIAGNOSTIC_TEST: Montreal Cognitive assesment (MoCA)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy of Corticosteroids to Treat Outpatients With Acute Exacerbations of COPD
Status: COMPLETED
Conditions: Pulmonary Disease|Chronic Obstructive (MeSH)
Interventions: DRUG: Prednisone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of an Immunotherapeutic, DPX-Survivac, in Combination With Low Dose Cyclophosphamide & Pembrolizumab, in Subjects With Selected Advanced & Recurrent Solid Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Ovarian Cancer|Hepatocellular Carcinoma|Non-small Cell Lung Cancer|Bladder Cancer|Microsatellite Instability-High
Interventions: OTHER: DPX-Survivac|DRUG: Cyclophosphamide|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Budesonide for Immunosuppression After Liver Transplantation to Reduce Side Effects
Status: WITHDRAWN
Conditions: Acute Cellular Graft Rejection|Liver Transplant Rejection
Interventions: DRUG: Budesonide|DRUG: Tacrolimus（FK506）|DRUG: Mycophenolate Mofetil|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pembrolizumab + Poly-ICLC in MRP Colon Cancer
Status: COMPLETED
Conditions: Metastatic Colon Cancer|Solid Tumor
Interventions: DRUG: pembrolizumab|DRUG: Poly-ICLC
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Continuous Infusion of Ropivacaine Hydrochloride in Reducing Pain After Surgery in Patients With Bladder Cancer
Status: WITHDRAWN
Conditions: Bladder Carcinoma|Post-operative Pain
Interventions: OTHER: Placebo|OTHER: Questionnaire Administration|DRUG: Ropivacaine Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluate the TetraLens, a Tetracaine Releasing Therapeutic Bandage Contact Lens in Patients Undergoing PRK Procedure
Status: COMPLETED
Conditions: Ocular Pain
Interventions: DRUG: TetraLens bandage contact lens|DEVICE: Control Acuvue Oasys Bandage contact Lens
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Benefits of Dry Needling in Trigger Points on Autonomic Nervous System and Corporal Composition in Patients With Fibromyalgia Syndrome
Status: COMPLETED
Conditions: Fibromyalgia|Trigger Points
Interventions: OTHER: Dry Needling Therapy|OTHER: Electrical Stimulation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dendritic Cell Vaccine for Children and Adults With Sarcoma
Status: COMPLETED
Conditions: Sarcoma|Soft Tissue Sarcoma|Bone Sarcoma
Interventions: BIOLOGICAL: Dendritic Cells Vaccine|BIOLOGICAL: Lysate of Tumor|DRUG: Gemcitabine|DRUG: Imiquimod|PROCEDURE: Leukapheresis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hyperbaric Oxygen Therapy for Ulcerative Colitis
Status: RECRUITING
Conditions: Ulcerative Colitis
Interventions: DEVICE: Hyperbaric Oxygen Therapy|OTHER: Sham Hyperbaric Air
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Proof of Mechanism Study for the Treatment of Social Anhedonia in ASD
Status: ACTIVE_NOT_RECRUITING
Conditions: ASD
Interventions: DRUG: L-DOPA versus Placebo|BEHAVIORAL: Social Skills Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Salmonella Conjugates CVD 1000: Study of Responses to Vaccination With Trivalent Invasive Salmonella Disease Vaccine
Status: COMPLETED
Conditions: Risk Reduction
Interventions: BIOLOGICAL: Trivalent Invasive Salmonella Disease Vaccine (6.25 µg)|BIOLOGICAL: Trivalent Invasive Salmonella Disease Vaccine (12 µg)|BIOLOGICAL: Trivalent Invasive Salmonella Disease Vaccine (25 µg)|BIOLOGICAL: Trivalent Invasive Salmonella Disease Vaccine (highest, well-tolerated dose among Cohorts A-C)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Audiological Benefit and Improved Quality of Life With Two Bone Conduction Systems: ADHEAR vs. Bonebridge in Experienced Users
Status: COMPLETED
Conditions: Bone Conduction Deafness|Hearing Loss, Conductive
Interventions: DEVICE: Adhesive bone conduction hearing aid (ADHEAR - Med El)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Versus Late Bronchoscopy in Bone Marrow Transplantation (BMT) Patients
Status: COMPLETED
Conditions: Bone Marrow Transplantation
Interventions: PROCEDURE: Variation in the time for performing bronchoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy Of Scalp Block And Ultrasound Guided TAP Block With Clonidine As Adjuvant To Ropivacaine Versus Intravenous Fentanyl On Intraoperative Hemodynamics And Perioperative Analgesia In Abdominal Bone Flap Cranioplasties
Status: COMPLETED
Conditions: Condition: Abdominal Bone Flap Cranioplasty; Focus of Study: Perioperative Analgesia
Interventions: PROCEDURE: Unilateral Scalp Block|PROCEDURE: Transversus abdominis plane block|DRUG: Intravenous Fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Change in Social Media Use and Well-being Among College Students Receiving a One-week Exercise or Mindfulness Intervention
Status: RECRUITING
Conditions: Social Media Addiction|Depression, Anxiety|Well-Being, Psychological
Interventions: BEHAVIORAL: Mindfulness|BEHAVIORAL: Social Media Reduction + Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Modular Trial of sEphB4-HSA in EphrinB2-High Solid Tumors
Status: NOT_YET_RECRUITING
Conditions: Muscle-Invasive Bladder Carcinoma|Metastatic Urothelial Carcinoma
Interventions: DRUG: SEphB4-HSA|DRUG: Pembrolizumab|DRUG: Gemcitabine|DRUG: Cisplatin|DRUG: Enfortumab vedotin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Inhaled Nitric Oxide on Deadspace in COPD
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Nitric Oxide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Analyzing the Pharmacodynamic Substances and the Effects of Yiqihuayu Decotion for Acute Ischemic Stroke (PHYSIS)
Status: UNKNOWN
Conditions: Ischemic Stroke, Acute
Interventions: DRUG: Yiqihuayu Decotion
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: B002 in Patients With HER2-positive Breast Cancer
Status: COMPLETED
Conditions: Recurrent Breast Cancer|Metastatic Breast Cancer
Interventions: BIOLOGICAL: Humanized Anti-HER2 Monoclonal Antibody Compound for Injection .R&D code: B002.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigation of the Effect of Exercise Training on Psychosocial Outcomes in Rotator Cuff Tears
Status: COMPLETED
Conditions: Rotator Cuff Tears|Pain, Shoulder|Psychological
Interventions: OTHER: Supervised exercise program|DIAGNOSTIC_TEST: Home exercise program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Quality of Life of Caregivers of Addicts
Status: NOT_YET_RECRUITING
Conditions: Addiction
Interventions: OTHER: 1-WHOQOL-BREF(WHO-Quality of life-BREFF) Arabic version Scale|OTHER: SCL-90-R(Symptoms Checklist-90-Revised) Arabic version scale|OTHER: addiction severity index
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparative Study Between Nifedipine and Ritodrine as Maintenance Tocolytic Therapy in Preterm Labor
Status: COMPLETED
Conditions: Preterm Birth
Interventions: DRUG: Nifedipine 20 Mg|DRUG: Ritodrine Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: IPL and MGX Versus MGX Alone in the Treatment of Dry Eye Disease Secondary to MGD
Status: COMPLETED
Conditions: Dry Eye|Meibomian Gland Dysfunction
Interventions: DEVICE: Intense Pulsed Light (IPL) therapy|DEVICE: Sham therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Vibration and Post-traumatic Osteoarthritis Risk Following ACL Injury
Status: RECRUITING
Conditions: Osteoarthritis, Knee|Anterior Cruciate Ligament Injuries|Post-traumatic Osteoarthritis|Quadriceps Muscle Atrophy
Interventions: DEVICE: Experimental: Whole Body Vibration|DEVICE: Experimental: Local Muscle Vibration|OTHER: Standard ACL Rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Radiographic and Patient Outcomes Following Lumbar Spine Fusion Using Demineralized Bone Matrix (DBM) Mixed With Autograft
Status: TERMINATED
Conditions: Stenosis|Spondylolisthesis|Degenerative Disc Disease
Interventions: PROCEDURE: Posterior Lateral Fusion (PLF)|PROCEDURE: Anterior Lumbar Interbody Fusion (ALIF)|PROCEDURE: Transforaminal lumbar interbody fusion (TLIF)|PROCEDURE: Posterior lumbar interbody fusion (PLIF)|PROCEDURE: Extreme lateral interbody fusion (XLIF)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Optimal Method of Fascial Closure in High Risk Patients Undergoing Laparotomy
Status: UNKNOWN
Conditions: Fascial Closure
Interventions: OTHER: Continuous suture|OTHER: Interrupted suture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Amblyopia and Stereoptic Games for Vision
Status: ACTIVE_NOT_RECRUITING
Conditions: Amblyopia|Healthy
Interventions: DEVICE: Vivid Vision Home|BEHAVIORAL: Refractive error correction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: AposTherapy for Singaporean Patients With Knee Osteoarthritis (OA)
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: DEVICE: AposTherapy (All Phases of Step-cycle {APOS} system, APOS-Medical and Sports Technologies Ltd. Herzliya, Israel)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Personnalized Transcranial Direct Current Electrical Stimulation (tDCS) in Drug-resistant Epileptic
Status: NOT_YET_RECRUITING
Conditions: Epilepsy|Drug Resistant Epilepsy
Interventions: DEVICE: transcranial direct current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Investigating the Effects of Iron on the Gastrointestinal Tract
Status: NOT_YET_RECRUITING
Conditions: Iron Deficiency Anemia|Constipation
Interventions: OTHER: Fasted breath samples|OTHER: IBS-SSS|OTHER: Daily diary|OTHER: Exploratory research: stool samples
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study in Healthy Men Tests How Different Doses of BI 764198 Are Taken up in the Body and How Well They Are Tolerated.
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BI 764198|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: XIENCE PRIME Everolimus Eluting Coronary Stent System (EECSS) China Single-Arm Study
Status: COMPLETED
Conditions: Angioplasty|Cardiovascular Disease|Coronary Artery Disease|Coronary Heart Disease|Coronary Restenosis|Myocardial Infarction|Stent Thrombosis|Vascular Disease
Interventions: DEVICE: XIENCE PRIME Everolimus Eluting Coronary Stent System (EECSS)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Preoperative Microbial Reduction of the Nasal Cavity With Antimicrobial Photodynamic Therapy (aPDT).
Status: NOT_YET_RECRUITING
Conditions: Efficacy of Preoperative Microbial Reduction in the Nasal Cavity Using Antimicrobial Photodynamic Therapy (aPDT)
Interventions: DEVICE: activated Light Source (aPDT)|DEVICE: non activated Light Source (Control)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Dexamethasone & Ketamine as Adjuvants to Bupivacaine for Incisional Infiltration in Pediatric Abdominal Operations
Status: COMPLETED
Conditions: Pediatric ALL
Interventions: DRUG: Bupivacaine|DRUG: Ketamine|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity of a JE-CV as a Booster Dose After a Primary Vaccination With SA14-14-2 Vaccine
Status: COMPLETED
Conditions: Japanese Encephalitis
Interventions: BIOLOGICAL: a live attenuated chimeric JE vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effects of Training Rhythmic and Discrete Aiming Movements on Arm Control and Functionality After Stroke
Status: UNKNOWN
Conditions: Stroke
Interventions: OTHER: Conventional Physical Therapy|OTHER: Discrete movement training group|OTHER: Rhythmic movement training group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Single-drug Chemotherapy Plus Immunotherapy in Metastatic Non-small Cell Lung Cancer Elderly Patients
Status: RECRUITING
Conditions: Elderly Patients|Metastatic Lung Cancer
Interventions: DRUG: Single drug chemotherapy plus immunotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase II Trial to Evaluate the Efficiency and Safety of Serplulimab Plus Chemotherapy as Conversion Therapy in NSCLC
Status: RECRUITING
Conditions: Unresectable Lung Non-Small Cell Carcinoma
Interventions: PROCEDURE: serplulimab plus chemotherapy as conversion treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Nitric Oxide for Inhalation in Right Ventricular Infarction Patients
Status: TERMINATED
Conditions: Right Ventricular Infarction
Interventions: DRUG: inhaled nitric oxide|DRUG: nitrogen gas
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Psychological Interventions in Haemophilia
Status: COMPLETED
Conditions: Haemophilia
Interventions: BEHAVIORAL: Hypnosis|BEHAVIORAL: Cognitive-Behavioral Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE