pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Estradiol and Testosterone Levels in Seminal Plasma of Men With Non-obstructive Azoospermia
Status: COMPLETED
Conditions: Non-obstructive Azoospermia With Testicular Biopsy for Spermatozoa Extraction
Interventions: OTHER: ESTRADIOL
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy of Steroids on Functional Outcomes After Musculoskeletal Injuries of the Hand
Status: UNKNOWN
Conditions: Hand Injuries|Finger Injuries
Interventions: DRUG: Methylprednisolone Tablet|OTHER: Standard Mobilization Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Can Remote Ischaemic Preconditioning Reduce Contrast Induced Nephropathy in Patients Receiving Contrast for Computed Tomography?
Status: COMPLETED
Conditions: Contrast Induced Nephropathy|Remote Ischaemic Preconditioning
Interventions: PROCEDURE: Remote ischaemic preconditioning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Group Reminiscence Therapy for Elderly People With Cognitive Decline in Institutional Context
Status: UNKNOWN
Conditions: Cognitive Decline|Dementia|Cognitive Impairment
Interventions: OTHER: Reminiscence Therapy Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase II Clinical Trial of YH23537 in Patients With Chronic Periodontal Disease.
Status: COMPLETED
Conditions: Chronic Periodontitis
Interventions: DRUG: YH23537 1000mg/day|DRUG: YH23537 2000mg/day|DRUG: YH23537 3000mg/day|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Combination Therapies for Gonorrhea Treatment
Status: COMPLETED
Conditions: Gonorrhoea
Interventions: DRUG: Azithromycin|DRUG: Gentamicin|DRUG: Gemifloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Osteoarthritis of the Hip Joint With Intra-articular Injection of Microfractured Autologous Adipose Tissue Containing Mesenchymal Stromal Cells.
Status: RECRUITING
Conditions: Hip Osteoarthritis|Hip Disease
Interventions: PROCEDURE: Micro-fragmented adipose tissue injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Focused Power Ultrasound Mediated Inferior Perirenal Adipose Tissue Modification Therapy for Essential Hypertension
Status: TERMINATED
Conditions: Hypertension|Blood Pressure|Cardiovascular Diseases
Interventions: DEVICE: focused power ultrasound mediate inferior perirenal adipose tussue modification|DEVICE: sham-control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: VGH-DESJS-1 in Ocular and Oral Dryness Symptoms of Dry Eye Syndrome and Sjögren's Syndrome
Status: COMPLETED
Conditions: Dry Eye Syndrome|Sjogren's Syndrome|Xerophthalmia
Interventions: OTHER: Chinese herbal tea VGH-DESJS-1
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Preventing Weight Regain Post-Semaglutide Treatment With Active Fiber Supplement (Soloways)
Status: COMPLETED
Conditions: Overweight and Obesity
Interventions: DIETARY_SUPPLEMENT: Active Fiber Supplement Group|OTHER: Placebo Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I Clinical Study of Recombinant Humanized Anti-BTLA Monoclonal Antibody (JS004) Injection Combined With Toripalimab Injection in Patients With Advanced Solid Tumors
Status: RECRUITING
Conditions: Liver Cancer, Esophageal Squamous Cell Carcinoma, Gastric Adenocarcinoma, Cervical Cancer, MSI-H Colorectal Cancer
Interventions: DRUG: JS004|DRUG: Toripalimab Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess on a Molecular Level the Influence of a 5 % Dexpanthenol Ointment in Subjects With Superficial Injuries
Status: COMPLETED
Conditions: Wound Healing|Cell Proliferation|Gene Expression
Interventions: DRUG: Dexpanthenol (BAY81-2996)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study Evaluating the Efficacy and Safety of Adjuvant Giredestrant Compared With Physician's Choice of Adjuvant Endocrine Monotherapy in Participants With Estrogen Receptor-Positive, HER2-Negative Early Breast Cancer (lidERA Breast Cancer)
Status: RECRUITING
Conditions: Early Breast Cancer
Interventions: DRUG: Giredestrant|DRUG: Endocrine Therapy of Physician's Choice|DRUG: LHRH Agonist|DRUG: Abemaciclib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Incidence, Risk Factors and Outcomes of Diaphragm Dysfunction After Lung Transplantation
Status: COMPLETED
Conditions: Diaphragm Injury|Lung Transplant; Complications, Mechanical|Respiratory Failure|Mechanical Ventilation Complication
Interventions: DIAGNOSTIC_TEST: Ultrasound|DIAGNOSTIC_TEST: Respiratory function measurements
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: ASP1517 Phase 2 Clinical Trial - Double-Blind Study of ASP1517 for the Treatment of Anemia in Chronic Kidney Disease Patients Not on Dialysis-
Status: COMPLETED
Conditions: Anemia in Chronic Kidney Disease Patients Not on Dialysis
Interventions: DRUG: ASP1517|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 3 28-Week Study With 24-Week and 52-week Extension Phases to Evaluate Efficacy and Safety of Exenatide Once Weekly and Dapagliflozin Versus Exenatide and Dapagliflozin Matching Placebo
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: DRUG: Exantide with Dapagliflozin|DRUG: Exentide|DRUG: Dapagliflozin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study (Candesartan 8 mg and Amlodipine 5 mg)
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: CKD-330 8/5mg|DRUG: Candesartan 8mg and Amlodipine 5mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High-Dose Isoniazid Adjuvant Therapy for Multidrug Resistant Tuberculosis
Status: COMPLETED
Conditions: Tuberculosis, Multidrug-Resistant
Interventions: DRUG: Isoniazid|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Prospective Real-World Multi-Center Post-Market Observational Evaluation of Supersaturated O2 Therapy Using the TherOx® Downstream® System
Status: TERMINATED
Conditions: Anterior Acute Myocardial Infarction (AMI)
Interventions: DEVICE: Supersaturated O2 Therapy of the Therox Downstream System®|PROCEDURE: PCI alone
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of RC48-ADC Combination With Zimberelimab Injection Therapies at Least First-line Platinum-containing Standard Therapy Failed With Recurrent or Metastatic Cervical Cancer
Status: RECRUITING
Conditions: Cervical Cancer
Interventions: DRUG: Disitamab Vedotin|DRUG: Zimberelimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Prospective, Randomized Clinical Trial of PRP Concepts Fibrin Bio-Matrix in Non-Healing Diabetic Foot Ulcers
Status: UNKNOWN
Conditions: Diabetic Foot Ulcers
Interventions: DEVICE: PRP Concepts Fibrin Bio-Matrix|OTHER: Usual and Customary Practice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Deep Brain Stimulation (DBS) for the Treatment of Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DEVICE: Deep Brain Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Band-Aid on Nausea-Vomiting During Pregnancy
Status: RECRUITING
Conditions: Nausea Gravidarum|Vomiting of Pregnancy|Pregnancy Related|Acupressure
Interventions: BEHAVIORAL: Band-aid application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Transplant Renal Artery Stenosis: Observation Versus Stenting
Status: RECRUITING
Conditions: Transplant Renal Artery Stenosis
Interventions: DIAGNOSTIC_TEST: Intra-arterial digital subtraction angiography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Pharmacokinetics and Safety of Inaxaplin in Participants With Mild or Moderate Hepatic Impairment
Status: RECRUITING
Conditions: Hepatic Impairment
Interventions: DRUG: IXP
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Fixation Stability and Bony Healing Following Open Wedge High Tibial Osteotomy
Status: COMPLETED
Conditions: Opening Wedge High Tibial Osteotomy
Interventions: PROCEDURE: High tibial osteotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Omalizumab as Monotherapy and as Adjunct Therapy to Multi-Allergen OIT in Food Allergic Participants
Status: ACTIVE_NOT_RECRUITING
Conditions: Peanut Allergy|Multi-food Allergy
Interventions: DRUG: Omalizumab|DRUG: Placebo for Omalizumab|DRUG: Multi-Allergen Oral Immunotherapy|DRUG: Placebo for Multi-Allergen Oral Immunotherapy|OTHER: Double-Blind Placebo-Controlled Food Challenge Based Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: GCIV as an Adjuvant Therapy for Community-Acquired Severe Sepsis or Septic Shock
Status: TERMINATED
Conditions: Severe Sepsis|Septic Shock
Interventions: DRUG: Immunoglobulin G
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Pre-surgery Gemcitabine + Hydroxychloroquine (GcHc) in Stage IIb or III Adenocarcinoma of the Pancreas
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DRUG: Hydroxychloroquine|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect Of Pelvic Floor Muscle Training With Biofeedback And Extracorporeal Magnetic Innervation On The Urinary Symptoms, Sexual Function And Quality Of Life
Status: COMPLETED
Conditions: Urinary Incontinence
Interventions: DEVICE: Pelvic Floor Muscle Training With Biofeedback|DEVICE: Extracorporeal Magnetic Innervation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Bioequivalence Study of Cefadroxil Film Coated Tablets After A Single Oral Dose Administration to Healthy Subjects
Status: COMPLETED
Conditions: Infections, Urinary Tract
Interventions: DRUG: Cefadroxil tablets manufactured by GSK|DRUG: Cefadroxil tablets manufactured by NP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Single-center Pilot Study Evaluating the Immediate Effects of Low-dose Acetazolamide on Respiratory Control in Subjects With Treatment Emergent Sleep Disordered Breathing
Status: WITHDRAWN
Conditions: Sleep Apnea
Interventions: DRUG: Acetazolamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improvements in Thyroid Tumor Surgery and the Prognosis, Diagnosis, Recurrence and Metastasis of Patients
Status: RECRUITING
Conditions: Papillary Thyroid Cancer|Lymph Node Metastasis|Carcinogenesis
Interventions: PROCEDURE: Suturing the cervical linea alba during endoscopic thyroid surgery.|GENETIC: Performing transcriptome sequencing
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Develop a Screening Tool for Functional Capacity in Anemic Subjects With Nonmyeloid Malignancies Receiving Chemotherapy and Darbepoetin Alfa
Status: COMPLETED
Conditions: Anemia|Non-Myeloid Malignancies
Interventions: DRUG: darbepoetin alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acupuncture for Blunt Chest Trauma
Status: COMPLETED
Conditions: Chest Trauma|Rib Fractures
Interventions: OTHER: Press Tack Acupuncture|OTHER: Press Tack Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cyclophosphamide Added to Standard Immunosuppressive Therapy With Herombopag as Front-line Therapy in Patients With Severe Aplastic Anemia
Status: RECRUITING
Conditions: Severe Aplastic Anemia
Interventions: DRUG: Cyclophosphamide added to standard immunosuppressive therapy with herombopag
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prednisolone Priming Study in Patients With Chronic Hepatitis B
Status: UNKNOWN
Conditions: Chronic Hepatitis B
Interventions: DRUG: Prednisolone|DRUG: Placebo priming
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Dovitinib Versus Sorafenib in Adult Patients With Hepatocellular Carcinoma (HCC) as a First Line Treatment
Status: COMPLETED
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: dovitinib|DRUG: sorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A 3-arm Multi-center, Randomized Controlled Study Comparing Transforaminal Corticosteroid, Transforaminal Etanercept and Transforaminal Saline for Lumbosacral Radiculopathy
Status: COMPLETED
Conditions: Lumbosacral Radiculopathy
Interventions: DRUG: etanercept|DRUG: methylprednisolone|DRUG: normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Heavy-slow Resistance Training and Ultrasound-guided Corticosteroid Injection in Plantar Fasciopathy
Status: COMPLETED
Conditions: Plantar Heel Pain|Plantar Fasciopathy
Interventions: OTHER: HSR|DRUG: Corticosteroid injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Comparison of Biodentine and MTA Pulpotomies in the Primary Molar Teeth 3 Year Follow up
Status: COMPLETED
Conditions: Pulpotomy|Dental Caries
Interventions: DRUG: Biodentine|DRUG: ProRoot (Aggregate)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility and Safety Study of Parent-to-Child Nasal Microbiota Transplant
Status: ACTIVE_NOT_RECRUITING
Conditions: Staphylococcus Aureus|Microbial Colonization|Neonatal Infection
Interventions: BIOLOGICAL: nasal microbiota transplant (NMT)|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Virtually Augmented Self Hypnosis in Peripheral Vascular Interventions
Status: COMPLETED
Conditions: Anxiety Postoperative|Pain, Postoperative|Vascular Access Site Pain
Interventions: DEVICE: OnComfort autohypnosis|OTHER: Treatment as usual, without the OnComfort autohypnosis system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nutritional Supplements and Nitric Oxide Bioactivity
Status: COMPLETED
Conditions: Nitric Oxide|Vascular Function|L-Arginine|Nitrate / Nitrite|Postprandial Metabolism
Interventions: DIETARY_SUPPLEMENT: L-Arginine|DIETARY_SUPPLEMENT: Nitrate / Nitrite|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy & Safety of Prophylaxis With Bemiparin in Cancer Patients With a Central Venous Catheter (BECAT)
Status: TERMINATED
Conditions: Cancer|Thrombosis
Interventions: DRUG: Bemiparin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: The Efficacy of Automated Feedback After Internet-based Depression Screening
Status: COMPLETED
Conditions: Depression|Major Depressive Disorder
Interventions: BEHAVIORAL: tailored feedback of depression screening results|BEHAVIORAL: standardized feedback of depression screening results
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: m-VISTA Technique vs. CAF in the Treatment of Class III Multiple Recessions
Status: COMPLETED
Conditions: Gingival Recessions
Interventions: PROCEDURE: Modified vestibular incision subperiosteal tunnel access|PROCEDURE: Coronally advanced flap
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics Safety and Acceptability of DRV/r for Children Living With HIV
Status: NOT_YET_RECRUITING
Conditions: HIV Infections
Interventions: DRUG: DRV/r FDC (120/20mg)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Study of MDX-010 (CTLA-4) Alone and Combined With Docetaxel in the Treatment of Patients With Hormone Refractory Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: MDX-010 / MDX-010 + Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of a Supervised Physical Therapy Rehabilitation Program vs Nonsupervised in Non-specific Low Back Pain
Status: COMPLETED
Conditions: Low Back Pain|Physical Activity
Interventions: OTHER: Supervised exercise program|OTHER: Non supervised exercise program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Pain, Anxiety and Efficiency of NumBee Compared to Traditional Local Anesthetic Syringe
Status: COMPLETED
Conditions: Dental Phobia|Dental Anxiety|Anesthesia, Local|Needle Phobia
Interventions: DEVICE: dental syringe ( NumBee)|DEVICE: Traditional dental syringe
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Comparison of Efficacy and Safety of Azelaic Acid 15% Gel With Its Vehicle in Subjects With Mild to Moderate Acne
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: Azelaic Acid Gel 15% (Finacea, BAY39-6251)|DRUG: Vehicle gel (SH H 655 PBA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Lavender Oil on Fatigue and Sleep Quality
Status: RECRUITING
Conditions: Hematologic Malignancies|Patient Participation
Interventions: OTHER: Lavander oil Aromatherapy|OTHER: Saline Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparing Nifuroxazide Plus Lactulose With Lactulose Alone in the Treatment of Hepatic Encephalopathy
Status: RECRUITING
Conditions: Hepatic Encephalopathy
Interventions: DRUG: Nifuroxazide|DRUG: Lactulose|DRUG: Rifaximin 550Mg Tab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Peripheral Internal Jugular Vein ('Peripheral IJ') Access in Patients Identified as Difficult Intravenous Access
Status: COMPLETED
Conditions: Difficult IV Access
Interventions: PROCEDURE: peripheral IV access procedure|PROCEDURE: Peripheral IJ access procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of Staple Line Suturing in Laparoscopic Sleeve Gastrectomy
Status: UNKNOWN
Conditions: Laparoscopic Sleeve Gastrectomy
Interventions: PROCEDURE: Staple line suturing reinforcement methods - Plication and Over-sewing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Do Taping and Orthosis Affect Pain, Gait, or Functionality in Mild Knee Osteoarthritis?
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: BEHAVIORAL: Taping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Evaluate the Efficacy and Safety of Pimodivir in Combination With the Standard-of-Care Treatment in Adolescent, Adult, and Elderly Non-Hospitalized Participants With Influenza A Infection Who Are at Risk of Developing Complications
Status: TERMINATED
Conditions: Influenza A
Interventions: DRUG: Pimodivir 600 mg|DRUG: Placebo|OTHER: SOC Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Treatment Response on IgG4 Related Disease (IgG4RD)
Status: UNKNOWN
Conditions: Autoimmune Disease
Interventions: DRUG: Prednisone|DRUG: Prednisone and Mycophenolate mofetil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CETIS-I (CEra Traction Improves Spine-I)
Status: RECRUITING
Conditions: Lumbar Disc Herniation|Degenerative Spinal Stenosis|Spine Traction
Interventions: DEVICE: Ceragem Master V6 Traction|DEVICE: Physical therapy with standard traction device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I [18F]THK-5351 Positron Emission Tomography Study in Healthy Subjects and Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer Disease
Interventions: DRUG: [18F]THK-5351
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Ibrutinib or Idelalisib in Treating Patients With Persistent or Relapsed Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, or Non-Hodgkin Lymphoma After Donor Stem Cell Transplant
Status: WITHDRAWN
Conditions: Prolymphocytic Leukemia|Recurrent Chronic Lymphocytic Leukemia|Recurrent Non-Hodgkin Lymphoma|Recurrent Small Lymphocytic Lymphoma
Interventions: DRUG: Ibrutinib|DRUG: Idelalisib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of INFUSE® Bone Graft Compared to Autogenous Bone Graft for Vertical Ridge Augmentation
Status: WITHDRAWN
Conditions: Alveolar Bone Loss in Mandible|Edentulous Alveolar Ridge In Mandible
Interventions: DEVICE: INFUSE® Bone Graft|PROCEDURE: Autogenous bone graft from tibia or iliac crest
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Different Modalities of Aquatic Physiotherapy in Patients With Knee Osteoarthrosis
Status: NOT_YET_RECRUITING
Conditions: Osteoarthritis of the Knee
Interventions: OTHER: Low impact immersion|OTHER: Conventional aquatic physiotherapy|OTHER: High intensity aquatic physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Busulfan and Cyclophosphamide Followed by Bone Marrow Transplantation in Treating Patients With Acute Myelogenous Leukemia or Myelodysplastic Syndrome
Status: COMPLETED
Conditions: Leukemia|Myelodysplastic Syndromes|Myelodysplastic/Myeloproliferative Diseases
Interventions: DRUG: busulfan|DRUG: cyclophosphamide|PROCEDURE: allogeneic bone marrow transplantation|PROCEDURE: bone marrow ablation with stem cell support|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I/II Study to Evaluate the Safety and Tolerability of LiPlaCis in Patients With Advanced or Refractory Tumours
Status: COMPLETED
Conditions: Phase 1: Advanced or Refractory Solid Tumours|Phase 2 Part: Metastatic Breast Cancer, Prostate Cancer and Skin Cancer
Interventions: DRUG: LiPlaCis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Psilocybin-Enhanced Psychotherapy for Methamphetamine Use Disorder
Status: RECRUITING
Conditions: Amphetamine-Related Disorders
Interventions: DRUG: Psilocybin|BEHAVIORAL: Treatment-as-usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: RCT of tDCS Combined With Cognitive Training in Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DEVICE: tDCS|BEHAVIORAL: Cognitive Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: HOPE at Heart (HOPE) of Donor Hearts After Circulatory Death (DCD) Using the XVIVO Heart Assist Transport System.
Status: NOT_YET_RECRUITING
Conditions: Heart Failure
Interventions: DEVICE: XVIVO Heart Assist Transport System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Epidural Technique: Does it Really Matter to the Patient?
Status: TERMINATED
Conditions: Anesthesia
Interventions: PROCEDURE: Dural puncture epidurals (DPE)|PROCEDURE: Traditional epidurals (EPI)|PROCEDURE: Combined-spinal epidural technique (CSE)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Winter-Swimming and Brown Adipose Tissue Activity in Middel-aged Obese Subjects (WinterBAT).
Status: ACTIVE_NOT_RECRUITING
Conditions: Adipose Tissue, Brown|Brown Adipose Tissue|Uncoupling Protein 1|Cold Exposure|Obesity|Type 2 Diabetes Mellitus|Winter Swimming
Interventions: BEHAVIORAL: Winter Swimming|BEHAVIORAL: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Multicenter Study for Robotic Arm-assisted THA 4.0 System: Hip Spine Relationship
Status: ACTIVE_NOT_RECRUITING
Conditions: Osteoarthritis, Hip|Hip Disease
Interventions: DEVICE: MAKO THA 4.0 System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multicenter Glaucoma Study Investigating Standalone Canaloplasty
Status: RECRUITING
Conditions: Primary Open Angle Glaucoma
Interventions: DEVICE: Ab-interno canaloplasty utilizing the iTrack Advance device|DEVICE: Ab-interno canaloplasty utilizing the OMNI Surgical System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study of the Safety of USB005 in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: USB005 (aclerastide) Ophthalmic Solution|DRUG: USB005 Ophthalmic Solution Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Intravenous Ferrous Sucrose on Exercise Capacity in Chronic Heart Failure
Status: UNKNOWN
Conditions: Chronic Heart Failure|Heart Diseases|Anemia, Iron-Deficiency
Interventions: DRUG: Venofer (intravenous iron sucrose)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Blood Pressure Lowering of Aliskiren Hydrochlorothiazide (HCTZ) Versus Amlodipine in Stage 2 Hypertension in African Americans
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Aliskiren Hydrochlorothiazide (HCTZ): 8 weeks|DRUG: Amlodipine: 8 weeks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Investigating Meningococcal Vaccines in Adults
Status: COMPLETED
Conditions: Meningococcal Vaccines|Meningococcal Infections|Neisseria Meningitidis|Factor H-binding Protein, Neisseria Meningitidi
Interventions: BIOLOGICAL: 4CMenB (Bexsero®) - Novartis Vaccines and Diagnostics
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Natural History of Depression, Bipolar Disorder and Suicide Risk
Status: RECRUITING
Conditions: Behavioral Symptoms|Suicide|Self-Injurious Behavior|Sensory System Agents|Analgesics|Peripheral Nervous System Agents|Physiological Effects of Drugs|Anesthetics, Dissociative|Anesthetics, General|Anesthetics|Central Nervous System Depressants|Excitatory Amino Acid Antagonists|Excitatory Amino Acid Agents|Neurotransmitter Agents|Molecular Mechanisms of Pharmacological Action|Ketamine|Depression, Unipolar|Depressive Symptoms|Treatment Resistant Depression|Major Depressive Disorder|Depression, Bipolar
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Exercise Training Effects on Metabolic Syndrome: Interactions With Medication
Status: COMPLETED
Conditions: Exercise Therapy|Metabolic Syndrome X|Cardiorespiratory Fitness
Interventions: DRUG: MEDICATION AND EXERCISE TRAINING
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Immersive Experience of Virtual Reality During Chemotherapy in Patients With Early Breast and Gynecological Cancers: the Patient's Dream Study
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DEVICE: 3 Virtual Reality headset (VR Headset),
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Venlafaxine Hydrochloride 150 mg Extended-Release Capsules Under Fasting Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Venlafaxine Hydrochloride|DRUG: Effexor® XR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: A Study to Evaluate the Efficacy and Safety of Liso-cel Compared to Standard of Care in Adults With Relapsed or Refractory Follicular Lymphoma
Status: NOT_YET_RECRUITING
Conditions: Relapsed or Refractory Follicular Lymphoma
Interventions: DRUG: Cyclophosphamide|DRUG: Doxorubicin|DRUG: Vincristine|DRUG: Rituximab|DRUG: Prednisone|DRUG: Bendamustine|DRUG: Lenalidomide|DRUG: Fludarabine|DRUG: Liso-cel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Control of Helicobacter Pylori Infection by Probiotics
Status: UNKNOWN
Conditions: Helicobacter Pylori Infection
Interventions: DIETARY_SUPPLEMENT: L. reuteri DSM 17938 and ATCC PTA 6475|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Relative Bioavailability With PF-05089771 Capsule Versus Oral Dispersion
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: PF-05089771|DRUG: PF-05089771|DRUG: PF-05089771
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of Xaluritamig in High-Risk, Biochemically Recurrent, Non-metastatic Castrate-sensitive Prostate Cancer
Status: NOT_YET_RECRUITING
Conditions: Prostate Cancer|High-risk Biochemical Recurrence|High Risk Biochemical Recurrence of Non-metastatic Castration-sensitive Prostate Cancer|Non-metastatic Castration-sensitive Prostate Cancer
Interventions: DRUG: Xaluritamig
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of AMG 596 in Patients With EGFRvIII Positive Glioblastoma
Status: COMPLETED
Conditions: Glioblastoma or Malignant Glioma
Interventions: DRUG: AMG 596|DRUG: AMG 404
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: LMA Placement Techniques and Airway in Children and Oropharyngeal Leak Pressure
Status: ACTIVE_NOT_RECRUITING
Conditions: Anesthesia|Airway
Interventions: PROCEDURE: Group 1|PROCEDURE: Group 2|PROCEDURE: Group 3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety, Tolerability and Immunogenicity of Meningococcal B Recombinant Vaccine Administered With or Without Routine Infant Vaccinations to Healthy Infants According to Different Immunization Schedules
Status: COMPLETED
Conditions: Meningococcal Infections
Interventions: BIOLOGICAL: rMenB+OMV NZ|BIOLOGICAL: combined diphtheria,tetanus,pertussis+polio+Hepatitis B+Haemophilus influenzae B vaccine|BIOLOGICAL: Pneumococcal vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Gastrointestinal Tolerance of D-allulose in Children
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: D-allulose|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Opioid Prescription After Cesarean Trial
Status: COMPLETED
Conditions: Pregnancy Related|Opioid Use|Pain
Interventions: DRUG: 0 to 20 tablets of oxycodone 5mg|DRUG: Fixed opioid prescription
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Botulinum-A Toxin Injection for Detrusor Hyperreflexia in Spinal Cord Injury: A Non-Surgical Approach.
Status: WITHDRAWN
Conditions: Overactive Bladder|Urinary Incontinence
Interventions: DRUG: Botox
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Feasibility Study of Radiation Therapy With Wide Detector 4DCT Scanning for Primary or Metastatic Lung Cancer
Status: COMPLETED
Conditions: the Diffenence of Different Detector Row 4DCT，Especially in Artifects，Radiation Dose and Target Volume
Interventions: OTHER: Extra 4DCT scan
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Chemotherapy Plus Radiation Therapy in Treating Patients With Stage II or Stage III Anal Cancer
Status: COMPLETED
Conditions: Anal Cancer
Interventions: DRUG: cisplatin|DRUG: fluorouracil|DRUG: mitomycin C|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Radical Cystectomy Compared With Chemoradiation for Muscle Invasive Bladder Cancer
Status: TERMINATED
Conditions: Muscle Invasive Bladder Cancer
Interventions: RADIATION: Radiation and chemoradiation|PROCEDURE: Radical cystectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Utility of Handheld Hydrogen Breathalyzer in Identification of Food Sensitivities (AIRE Study)
Status: ACTIVE_NOT_RECRUITING
Conditions: SIBO|Small Bowel Bacterial Overgrowth Syndrome
Interventions: DEVICE: Hydrogen content recording
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Improving Prostate Cancer Detection Using MRI-Targeted TRUS-Guided Biopsy
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DEVICE: TRUS-Guided Biopsy|DEVICE: MRI + TRUS-Guided Biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study in Healthy Adults to Evaluate Gene Activation After Vaccination With GlaxoSmithKline (GSK) Biologicals' Candidate Tuberculosis (TB) Vaccine GSK 692342
Status: COMPLETED
Conditions: Tuberculosis
Interventions: BIOLOGICAL: GSK Biologicals' investigational TB vaccine GSK 692342
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Vitamin D Treatment in Ulcerative Colitis
Status: WITHDRAWN
Conditions: Ulcerative Colitis|Inflammatory Bowel Disease
Interventions: DRUG: Vitamin D3|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Clincal Trial on the Effect of a Restricted Gluten Contamination Elimination Diet Among Celiacs [GluCED]
Status: COMPLETED
Conditions: Celiac Disease
Interventions: BEHAVIORAL: GCED, Gluten Contamination Elimination Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Postmarketing Study to Evaluate add-on Therapy With Anticholinergics in Patients With Overactive Bladder (OAB) on Mirabegron.
Status: COMPLETED
Conditions: Overactive Bladder (OAB)
Interventions: DRUG: Mirabegron tablet|DRUG: Solifenacin tablet|DRUG: Propiverine tablet|DRUG: Imidafenacin tablet|DRUG: Tolterodine capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics and Bioavailability of Pomegranate Phenolics and Urolithins in Healthy Subjects.
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Pomegranate extract|DIETARY_SUPPLEMENT: Pomegranate extract
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Facilitated Vegan Diet on Cardiometabolic Endpoints and Trimethylamine N-oxide
Status: UNKNOWN
Conditions: Cardiometabolic Risk Factors
Interventions: OTHER: Facilitated Vegan Diet|OTHER: Omnivorous Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparison of Landiolol Versus Standard of Care for Prevention of Mortality in Patients Hospitalized for a Septic Shock With Hypercontractility
Status: RECRUITING
Conditions: Septic Shock|Tachycardia|Mortality During Septic Shock|Beta-blocker
Interventions: OTHER: echocardiography|DRUG: Landiolol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Confocal Laser Microlaryngoscopy (CLMx)
Status: WITHDRAWN
Conditions: Laryngeal Dysplasia|Laryngeal Neoplasm
Interventions: DRUG: Fluorescein injection, USP 10%|DEVICE: Confocal laser microlaryngoscopy|PROCEDURE: Biopsy (standard of care)|PROCEDURE: KTP laser photoablation (standard of care)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: EPID Multiple Sclerosis Pregnancy Study
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DRUG: Betaseron (Interferon beta-1b, BAY86-5046), Bayer HealthCare AG|DRUG: Extavia (interferon beta-1b), Novartis Pharma AG|DRUG: Rebif (interferon beta-1a), Merck Serono Europe Ltd|DRUG: Plegridy (peginterferon beta-1a), Biogen Idec Ltd|DRUG: Avonex (interferon beta-1a), Biogen Idec Ltd|DRUG: MSDMDs other than Betaseron (Interferon beta-1b, BAY86-5046)|OTHER: No MSDMDs therapy (control)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety of Low-dose Ibrutinib and Itraconazole in Chronic Graft Versus Host Disease
Status: UNKNOWN
Conditions: Chronic Graft-versus-host-disease
Interventions: DRUG: Low-dose ibrutinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Tolerability, Safety, Pharmacodynamics, and Pharmacokinetics of Ascending Single Doses (Including Food Interaction) and Ascending Multiple Doses of ACT-453859, and Multiple Doses of Setipiprant (ACT-129968)
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: ACT-453859 1 mg|DRUG: ACT-453859 3 mg|DRUG: ACT-453859 10 mg|DRUG: ACT-453859 30mg|DRUG: ACT-453859 100 mg|DRUG: ACT-453859 300 mg|DRUG: ACT-453859 800 mg|OTHER: Placebo|DRUG: Setipiprant 500 mg|DRUG: Setipiprant 1000 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Study to Compare Adhesiveness of Two Different Rotigotine Patch Formulations
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DRUG: Rotigotine transdermal patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Gambling Disorder With Fast Acting Opiate Antagonist, Naloxone Nasal Spray
Status: COMPLETED
Conditions: Gambling|Opioid|Naloxone|Spray
Interventions: DRUG: Naloxone hydrochloride 20mg/ml
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 3-5 FrAction Stereotactic Body Radiation Therapy for Palliation of Head and Neck Squamous Cell Carcinoma: the FAST Phase II Randomized Trial
Status: RECRUITING
Conditions: Head and Neck Squamous Cell Carcinoma
Interventions: RADIATION: Stereotactic body radiotherapy|RADIATION: Traditional Palliation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Closed-Loop Strategies for Glucose Control in Type 1 Diabetes The DREMED Trail- 2
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: DEVICE: Advanced Hybrid Closed Loop System|DEVICE: Hybrid Closed Loop System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Erlotinib, Gemcitabine and Cisplatin in Metastatic Pancreatic Cancer
Status: COMPLETED
Conditions: Metastatic Pancreatic Cancer
Interventions: DRUG: Gemcitabine, Cisplatin, Erlotinib (Tarceva)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Erlotinib for Treatment of Psoriasis
Status: WITHDRAWN
Conditions: Psoriasis
Interventions: DRUG: erlotinib|OTHER: placebo tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Quality of Preanesthesia Teleconsultation : a Randomized Controlled Trial.
Status: UNKNOWN
Conditions: Preanesthesia Consultation
Interventions: PROCEDURE: preanesthesia teleconsultation|PROCEDURE: preanesthesia traditional consultation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Nasal Obstruction Compared by Rhinomanometry and Nasal Inspiratory Peak Flow After Endoscopic Nasal Surgery
Status: RECRUITING
Conditions: Pituitary Adenoma Invasive|Nasal Obstruction
Interventions: PROCEDURE: Nasal patency - rhinomanometry|PROCEDURE: Nasal patency - nasal inspiratory peak flow
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Priming Intervention to Increase Patient Willingness to Use Injectables for the Management of Psoriasis
Status: ACTIVE_NOT_RECRUITING
Conditions: Psoriasis
Interventions: BEHAVIORAL: Group #2 (Intervention)|BEHAVIORAL: Group #3 (Intervention)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH