pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Flow Sensor and Colourimetric Capnometer in Verifying Tracheal Tube Positioning in Term and Preterm Infants
Status: UNKNOWN
Conditions: Tracheal Intubation
Interventions: DEVICE: confirmation of endotracheal tube positioning
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Video Laryngoscopy Versus Direct Laryngoscopy for Nasotracheal Intubation
Status: RECRUITING
Conditions: Congenital Heart Disease|Airway Complication of Anesthesia
Interventions: DEVICE: laryngoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial of Pyridoxamine to Lower Urine Oxalate in Subjects With Stone Disease or Hyperoxaluria
Status: WITHDRAWN
Conditions: Kidney Stones
Interventions: DRUG: Pyridoxamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Effects of Two Concentrations of Adrenaline (0.33 mg/l vs 1 mg/l) in the Irrigation Serum of Arthroscopic Shoulder Surgery
Status: COMPLETED
Conditions: Shoulder Rotator Cuff Tendinitis
Interventions: DRUG: Adrenaline 0,33 Mg/mL Solution for Injection|DRUG: Adrenaline 1 Mg/mL Solution for Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Computerized Information-Processing Bias Retraining in Depressed Adolescents
Status: COMPLETED
Conditions: Major Depression
Interventions: BEHAVIORAL: Computerized Information-Processing Bias Retraining|BEHAVIORAL: Attention Control Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Genetic Risk Assessment for Cancer Education and Empowerment (GRACE) Project
Status: COMPLETED
Conditions: Breast Cancer|Ovarian Cancer
Interventions: BEHAVIORAL: Telephone Counseling & Navigation (TCN)|BEHAVIORAL: Mailed Targeted Print (TP)|OTHER: Usual Care (UC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Phase I Safety and Immunogenicity Trial of Live Recombinant Canarypox-gp160 MN (ALVAC vCP125, HIV-1 gp160 MN) in HIV-1 Uninfected Adult Volunteers
Status: COMPLETED
Conditions: HIV Infections
Interventions: BIOLOGICAL: ALVAC-HIV gp160MN (vCP125)|BIOLOGICAL: ALVAC-RG Rabies Glycoprotein (vCP65)|BIOLOGICAL: rgp120/HIV-1 SF-2
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of Polylevolactic Acid Injection Combined With 1565nm Non-ablative Fractional Laser in the Treatment of Striae Distensae
Status: RECRUITING
Conditions: Striae Distensae
Interventions: DEVICE: Polylevolactic Acid Injection|DEVICE: 1565nm Non-ablative Fractional Laser|DEVICE: Polylevolactic Acid Injection combined with 1565nm Non-ablative Fractional Laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: EMR Referrals for Teratogen and Contraceptive Counseling for Category D or X Medication Users: RCT
Status: COMPLETED
Conditions: Chemical Teratogen Exposure|Contraception Behavior|Contraception
Interventions: BEHAVIORAL: EMR Referral|BEHAVIORAL: CTIS Counseling|BEHAVIORAL: Baseline Questionnaire|BEHAVIORAL: Contraception Provision Appointment|BEHAVIORAL: 3 Month Follow Up Questionnaire|BEHAVIORAL: 6 Month Follow Up Questionnaire
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Recombinant Human Growth Hormone (RH-GH) For Accelerating Immune Reconstitution Post Unrelated Cord Blood Transplant
Status: TERMINATED
Conditions: Allogeneic Stem Cell Transplantation
Interventions: DRUG: Genotropin (Recombinant Human Growth Hormone)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Pembrolizumab in Combination With Doxorubicin in Advanced, Recurrent or Metastatic Endometrial Cancer
Status: COMPLETED
Conditions: Endometrial Neoplasms
Interventions: DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Skin Tolerance and Efficacy of a Cosmetic Product After 5 Days of Use on Subjects With Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Diathesis|Eczema-prone Skin
Interventions: OTHER: Atopi intensive care BNO 3731|OTHER: Benchmark product
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Effect of Curcumin on Gut Microbiota in IBS
Status: COMPLETED
Conditions: Irritable Bowel Syndrome
Interventions: DIETARY_SUPPLEMENT: Curcumin|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ozone Autohemotherapy for Ischemic Stroke Sleep Disorder
Status: UNKNOWN
Conditions: Post-ischemic Stroke Insomnia
Interventions: OTHER: ozone autohemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Bioavailability and Food Effect Study of TKI258 (CSF Capsule vs. FMI Tablet) in Adult Patients With Advanced Solid Tumors
Status: COMPLETED
Conditions: Neoplasm|Cancer|Tumors
Interventions: DRUG: TKI258
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Bioequivalence Study Comparing Two Different Tafamidis Formulations
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Tafamidis|DRUG: Tafamidis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Utidelone Capsule Plus Capecitabine (CAP) for Metastatic Breast Cancer
Status: RECRUITING
Conditions: Breast Cancer Recurrent
Interventions: DRUG: Utidelone Capsule Plus Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Changes in Streptococcus Mutans Colonization With Different Oral Hygiene Protocols in Adult Patients With Fixed Orthodontic Appliance
Status: RECRUITING
Conditions: S.Mutans Colonization in Adults With Fixed Orthodontic Appliance
Interventions: COMBINATION_PRODUCT: Chlorhexidine mouthwash|DEVICE: Interdental brush|OTHER: Fluoride-based toothpaste
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Behavioral Stress Reduction Programs on Blood Pressure in African American Youth
Status: COMPLETED
Conditions: Cardiovascular Diseases|Heart Diseases|Hypertension
Interventions: BEHAVIORAL: Mindfulness Meditation (MM) Program|BEHAVIORAL: Health Education Control Program (CTL)|BEHAVIORAL: Lifeskills Program (LP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effects of Empagliflozin + Linagliptin vs Metformin + Insulin Glargine on Renal and Vascular Changes in Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus Type 2
Interventions: DRUG: Empagliflozin and Linagliptin|DRUG: Metformin and Insulin sc
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Open-label, Single-arm, Multicenter, Phase II Study of RC48-ADC to Evaluate the Efficacy and Safety of Subjects With HER2 Overexpressing Locally Advanced or Metastatic Urothelial Cancer
Status: COMPLETED
Conditions: Urothelial Carcinoma
Interventions: DRUG: RC48-ADC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of ONSD and rSO2 Measurements Between General and Spinal Anesthesia in C-Section
Status: COMPLETED
Conditions: Intracranial Pressure Increase
Interventions: OTHER: Optic Nerve Sheath Diameter Measurement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pulmonary Hypertension on Prognosis of Acute Myocardial Infarction Patients With Reduced Left Ventricular Function
Status: COMPLETED
Conditions: Acute Myocardial Infarction|Pulmonary Hypertension
Interventions: OTHER: This was an observational study, and no Intervention was given to the patients.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Treatment Of Chronic Anal Fissure
Status: TERMINATED
Conditions: Chronic Anal Fissure
Interventions: OTHER: Levorag Emulgel|DRUG: Diltiazem
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Acceptability and Efficacy of 10 Micrograms of Estradiol Vaginal Tablets vs Promestriene Vaginal Cream
Status: COMPLETED
Conditions: Vulvovaginal Atrophy
Interventions: DRUG: Estradiol 10 MCG Vaginal Tablet [VAGIFEM]|DRUG: Promestriene Vaginal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Positron Emission Tomography Imaging of Brain Reorganisation of the Central Auditory Cortex in Asymetrical Profound Deaf Patient With a Cochlear Implantation.
Status: COMPLETED
Conditions: Profound Hearing Impairment
Interventions: OTHER: Positron emission tomography scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Multi-Center, Evaluation of the Onset and Duration of Action of AC-170 0.24% Compared to Vehicle
Status: COMPLETED
Conditions: Allergic Conjunctivitis
Interventions: DRUG: AC-170 0.24%|DRUG: AC-170 0%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Topical Bimatoprost Solution 0.03%in Stable Vitiligo
Status: WITHDRAWN
Conditions: Vitiligo|Repigmentation
Interventions: DRUG: Bimatoprost 0.03% topical ophthalmic solution
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: De Novo Lipogenesis of Sebaceous Glands in Acne
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: Tretinoin|DRUG: Isotretinoin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Evaluate the Long-Term Effect of TEV-48574 in Moderate to Severe Ulcerative Colitis or Crohn's Disease
Status: RECRUITING
Conditions: Crohn Disease|Colitis, Ulcerative
Interventions: DRUG: TEV-48574 Dose Regimen A|DRUG: TEV-48574 Dose Regiment B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Transcutaneous Electrical Nerve Stimulation for Postoperative Quality of Recovery After Shoulder Surgery
Status: RECRUITING
Conditions: Quality of Recovery
Interventions: DEVICE: Placebo-Transcutaneous Electrical Nerve Stimulation (TENS)|DEVICE: Transcutaneous Electrical Nerve Stimulation (TENS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Safety and Tolerability of a Single-dose Administration of BMI2004 Inj.
Status: COMPLETED
Conditions: Health, Subjective
Interventions: BIOLOGICAL: BMI2004|OTHER: 0.9% NaCl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: HEALEY ALS Platform Trial - Regimen F ABBV-CLS-7262
Status: ENROLLING_BY_INVITATION
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DRUG: ABBV-CLS-7262 Dose 1|DRUG: ABBV-CLS-7262 Dose 2|DRUG: Matching Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Examining Sex-based Differences in Metabolic and Mechanistic Responses to Disuse Induced Muscle Atrophy
Status: RECRUITING
Conditions: Muscle Atrophy|Muscle Disuse Atrophy
Interventions: PROCEDURE: Single Leg Immobilization
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of Bonviva (Ibandronate) and Alendronate on Renal Function in Postmenopausal Women With Osteoporosis at High Risk for Renal Disease.
Status: COMPLETED
Conditions: Post-Menopausal Osteoporosis
Interventions: DRUG: ibandronate [Bonviva/Boniva]|DRUG: ibandronate [Bonviva/Boniva]|DRUG: Alendronate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Stellate Ganglion Block on Meniere's Disease
Status: COMPLETED
Conditions: Vertigo|Meniere Disease
Interventions: PROCEDURE: stellate ganglion block|DRUG: 0.25mg, fludiazine|DRUG: 25mg cephadol@ (diphenidol)|DRUG: 200mg kentons@ (tocopherol nicotinate).
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Power of Curiosity: Leveraging Curiosity to Motivate People to Complete Health Risk Assessments
Status: COMPLETED
Conditions: Intention|Exploratory Behavior
Interventions: BEHAVIORAL: Curiosity Message|BEHAVIORAL: Standard Message
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Postmarketing Vedolizumab Milk-Only Lactation Study in Lactating Women With Active Ulcerative Colitis or Crohn's Disease
Status: COMPLETED
Conditions: Colitis, Ulcerative|Crohn's Disease
Interventions: DRUG: Vedolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Decentralized Clinical Trial to Promote Evidence-Based Care for Underserved Patients With Neurofibromatosis 1
Status: NOT_YET_RECRUITING
Conditions: Neurofibromatosis 1
Interventions: OTHER: Letters about NF1 Care (Content Type 1)|OTHER: Letters about NF1 Care (Content Type 2)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: HIgh Flow Versus NIV for Acute Cardiogenic PuLmonary Oedema With Acute Respiratory Failure in an ED
Status: COMPLETED
Conditions: Cardiogenic Pulmonary Edema
Interventions: DEVICE: Non invasive ventilation|DEVICE: High-flow nasal cannula heated and humidified oxygen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized, Double Blind Study To Compare The Effects Of Olmesartan Medoxomil Versus Placebo In Patients With Established Atherosclerosis
Status: COMPLETED
Conditions: Atherosclerosis
Interventions: DRUG: Olmesartan medoxomil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Cross-control Study on the Effect of Peritoneal Rest on Peritoneal Transport Function in Peritoneal Dialysis Patients
Status: RECRUITING
Conditions: Chronic Kidney Disease 5D
Interventions: COMBINATION_PRODUCT: peritoneal rest
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase Ib Study of the Recombinant Mycobacterium Tuberculosis Vaccine Freeze-dried (AEC/BC02)
Status: COMPLETED
Conditions: Tuberculosis
Interventions: BIOLOGICAL: Low-dose freeze-dried recombinant tuberculosis vaccine (AEC / BC02)|BIOLOGICAL: Low-dose adjuvant for freeze-dried recombinant tuberculosis vaccine (AEC / BC02)|BIOLOGICAL: Lyophilized recombinant tuberculosis vaccine (AEC / BC02) placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Interlaboratory Reliability of 3D Gait Analysis
Status: RECRUITING
Conditions: Gait Analysis|Reproducibility
Interventions: DEVICE: 3D gait analysis on the GRAIL|OTHER: Weight and height
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Acute Metabolic and Endocrine Responses of Glucose and Fructose in Healthy Young Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: fructose|DIETARY_SUPPLEMENT: glucose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: deLIVER: Direct Acting Antiviral Effects on the Liver
Status: COMPLETED
Conditions: HCV Coinfection|Liver Disease|HIV
Interventions: DRUG: Sofosbuvir/Velpatasvir/Voxilaprevir [SOF/VEL/VOX]|DRUG: Sofosbuvir/Velpatasvir (SOF/VEL)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: One Year Clinical Evaluation of New Gradient Technology Monolithic Zirconia (5Y-TZP/3Y-TZP) Crowns in Dental Esthetic Zone With Vertical Versus Conventional Preparation Techniques
Status: UNKNOWN
Conditions: Single Anterior Crowns|Badly Decayed Teeth|Endodontically Treated Teeth|Spacing Between Anterior Teeth|Malposed Teeth(Tilted,Overerupted,Totated,Etc.)
Interventions: PROCEDURE: Vertical preparation technique|PROCEDURE: Conventional Preparation technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability of PQ912 in Subjects With Early Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: PQ912 oral|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 3 Alogliptin Pediatric Study
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Alogliptin Benzoate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: HIV Viremia and Persistence in Acutely HIV-Infected Patients Treated With Darunavir/Ritonavir and Etravirine
Status: TERMINATED
Conditions: Acute HIV Infection|HIV Infections
Interventions: DRUG: Darunavir|DRUG: Ritonavir|DRUG: Etravirine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Disrupting Fear-based Memory Consolidation
Status: RECRUITING
Conditions: Post-Traumatic Stress Disorder
Interventions: OTHER: Continuous theta burst stimulation (cTBS)|OTHER: Sham continuous theta burst stimulation (cTBS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Alirocumab (REGN727/SAR236553) in Patients With Primary Hypercholesterolemia and Moderate, High, or Very High Cardiovascular (CV) Risk, Who Are Intolerant to Statins (ODYSSEY ALTERNATIVE)
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DRUG: Atorvastatin|DRUG: Ezetimibe|DRUG: Alirocumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Inflammation in Heart Failure
Status: WITHDRAWN
Conditions: Myocardial Dysfunction|Heart Failure|Inflammation
Interventions: DRUG: Dapagliflozin|DEVICE: MRI scan|DEVICE: CMR imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Recurrent Extrahepatic Bile Duct Stones as a Late Complication of ERCP in Patients With Coexisting Intra- and Extrahepatic Bile Duct Stones
Status: RECRUITING
Conditions: Intrahepatic Bile Duct Stone|Choledocholithiasis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Hydrocortisone for BPD
Status: ACTIVE_NOT_RECRUITING
Conditions: Infant, Newborn|Infant, Small for Gestational Age|Infant, Very Low Birth Weight|Infant, Premature|Bronchopulmonary Dysplasia
Interventions: DRUG: Hydrocortisone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Concomitant Curcumin Palliative Radiotherapy in Advanced Cervical Cancer Trial
Status: NOT_YET_RECRUITING
Conditions: Cervical Cancer
Interventions: DRUG: Curcumin|RADIATION: Palliative radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of MOD-4023 to Treat Children With Growth Hormone Deficiency
Status: COMPLETED
Conditions: Growth Hormone Deficiency
Interventions: DRUG: MOD-4023|DRUG: Genotropin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Cost-effectiveness of RFA vs. PEI for Early-stage HCC
Status: COMPLETED
Conditions: Cost Effectiveness|Exposure to Radiofrequency
Interventions: DEVICE: radiofrequency ablation|OTHER: percutaneous ethanol injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Stereotactic Radiosurgery in Treating Patients With Large Brain Metastases
Status: SUSPENDED
Conditions: Tumors Metastatic to Brain|Unspecified Adult Solid Tumor
Interventions: RADIATION: stereotactic radiosurgery|PROCEDURE: quality-of-life assessment|PROCEDURE: cognitive assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Natural History of Duchenne Muscular Dystrophy Cardiomyopathy (DMD-CMP)
Status: NOT_YET_RECRUITING
Conditions: Duchenne Muscular Dystrophy
Interventions: DIAGNOSTIC_TEST: Cardiac MRI|BIOLOGICAL: Blood assays
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Transcranial Alternating Current Stimulation for Treatment-Resistant Depression
Status: NOT_YET_RECRUITING
Conditions: Treatment-Resistant Depression
Interventions: DEVICE: transcranial alternating current stimulation (tACS)|DEVICE: Sham tACS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sedation Protocols and Skeletal Muscle Metabolism in Mechanical Ventilated Patients
Status: UNKNOWN
Conditions: Hypercatabolism|Sedative, Hypnotic, or Anxiolytic Use Disorders
Interventions: DRUG: Dexmedetomidine|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Impact of Lingual Frenotomy on Bottle Feeding Mechanics
Status: COMPLETED
Conditions: Ankyloglossia|Feeding, Bottle|Feeding Disorder of Infancy and Childhood
Interventions: PROCEDURE: Lingual frenotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endoesophageal Brachytherapy for Patients With Esophageal Cancer
Status: COMPLETED
Conditions: Esophageal Cancer
Interventions: DEVICE: Endoesophageal Brachytherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Cannabis Administration Routes on Human Performance and Pharmacokinetics
Status: COMPLETED
Conditions: Cannabis Use
Interventions: DRUG: Placebo + Placebo|DRUG: Oral Cannabis + Placebo|DRUG: Placebo + Inhaled Cannabis|DRUG: Placebo + Smoked Cannabis|DRUG: 6.9% cannabis oral
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Magnetotherapy in Rheumatoid Arthritis Treatment
Status: COMPLETED
Conditions: Rheumatoid Arthritis|Hand Rheumatism
Interventions: OTHER: Kinesiotherapy with magnetotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Intramuscular Administration of Scopolamine
Status: TERMINATED
Conditions: Scopolamine Causing Adverse Effects in Therapeutic Use
Interventions: DRUG: Scopolamine Hydrobromide Trihydrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Lung Nodule Detection Using Ultra-long FOV PET/CT
Status: UNKNOWN
Conditions: Lung Cancer
Interventions: DRUG: 18F-FDG|RADIATION: PET/CT imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Prediction and Prevention of Postoperative Mortality and Morbidity
Status: NOT_YET_RECRUITING
Conditions: Alzheimer Disease|Alzheimer Disease Related Dementias
Interventions: OTHER: Personalized CPC Prehabilitation|BEHAVIORAL: Cognitive Training|BEHAVIORAL: Meditation|BEHAVIORAL: Daily Exercise|BEHAVIORAL: Enhanced Social Support|OTHER: Proactive Bundle Interventions|PROCEDURE: Pre-operative Standard of Care|PROCEDURE: Intra-operative Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Neuroimmune Dysfunction in Alcohol Use Disorder
Status: COMPLETED
Conditions: Alcohol Drinking|Alcohol-Related Disorders|Disease|Inflammation|Alcoholism|Cognitive Dysfunction|Pathologic Processes|Drinking Behavior|Substance-Related Disorders|Chemically-Induced Disorders|Mental Disorder|Cognition Disorder|Neurocognitive Disorders|Minocycline|Anti-Bacterial Agents|Anti-Infective Agents
Interventions: DRUG: Minocycline|DRUG: Sugar pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial to Show Non-inferiority / Superiority of an Endoscopic Transforaminal Discectomy to Standard Microdiscectomy
Status: WITHDRAWN
Conditions: Lumbar Disc Herniation
Interventions: PROCEDURE: joimax TESSYS|PROCEDURE: Microdiscectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: NHLBI Transmural Electrosurgery LeafLet Traversal And Laceration Evaluation (TELLTALE) BASILICA-TAVR Trial
Status: RECRUITING
Conditions: Valvular Heart Disease|Aortic Valve Failure
Interventions: DEVICE: TELLTALE BASILICA procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of n-3 Polyunsaturated Fatty Acids Supplementation on Human Milk Composition of Lactating Women
Status: COMPLETED
Conditions: Nursing Women
Interventions: DIETARY_SUPPLEMENT: nutritional intervention|DIETARY_SUPPLEMENT: nutritional intervention|DIETARY_SUPPLEMENT: nutritional intervention|DIETARY_SUPPLEMENT: nutritional intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Avastin and Taxotere for Esophagogastric Cancer
Status: COMPLETED
Conditions: Esophageal Cancer|Gastric Cancer
Interventions: DRUG: Docetaxel|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: DEFLAGYN® Vaginal Gel and Spontaneous Remission and Regression of Unclear Cervical Smears and HPV High-risk Infections
Status: RECRUITING
Conditions: Cervix Dysplasia|HPV Infection
Interventions: DEVICE: DEFLAGYN vaginal gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: OLP-1002 is Being Studied in the Treatment of Pain.
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: OLP-1002 (Test): Part A, Single Ascending Dose|DRUG: OLP-1002 (Test): Part B, Multiple Ascending Dose|OTHER: Placebo: Placebo Part A, Single Ascending Dose|OTHER: Placebo: Placebo Part B, Multiple Ascending Dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Lithium on Suicide Prevention in Adolescents and Young Adults With Bipolar Disorder in China
Status: RECRUITING
Conditions: Bipolar Disorder|Suicidal Ideation|Suicide, Attempted|Nonsuicidal Self Injury
Interventions: DRUG: Lithium Carbonate|DRUG: Non-lithium medication
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Tazemetostat and Pembrolizumab in Patients With Pembrolizumab- or Nivolumab-Resistant, Recurrent or Metastatic Head and Neck Squamous-Cell Carcinoma
Status: TERMINATED
Conditions: Head and Neck Squamous Cell Carcinoma
Interventions: DRUG: Tazemetostat|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Fenofibrate as a Treatment for Huntington's Disease
Status: COMPLETED
Conditions: Huntington Disease
Interventions: DRUG: Fenofibrate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase III Study of 5tx vs 15tx of RT (X-rays or Protons) Including RNI in Breast Cancer Patients
Status: RECRUITING
Conditions: Anatomic Stage I Breast Cancer AJCC v8|Anatomic Stage II Breast Cancer AJCC v8|Anatomic Stage III Breast Cancer AJCC v8
Interventions: RADIATION: Proton Beam Radiation Therapy|OTHER: Questionnaire Administration|RADIATION: X-ray Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cognizin Citicoline Dosing in a Healthy Adolescent Male Population
Status: COMPLETED
Conditions: Neurocognitive Improvement
Interventions: DRUG: Citicoline|OTHER: Microcrystalline Cellulose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dual Implant Versus Single Implant Distal End of Femur
Status: ENROLLING_BY_INVITATION
Conditions: Distal Femur Fracture
Interventions: PROCEDURE: Single distal femur implant|PROCEDURE: Dual distal femur implants
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Study of Montelukast for the Treatment of Sickle Cell Anemia
Status: COMPLETED
Conditions: Sickle Cell Anemia (HbSS, or HbSβ-thalassemia0)
Interventions: DRUG: Montelukast added to Hydroxyurea|DRUG: Placebo added to Hydroxyurea
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Two Approved Drugs in the Treatment of Postoperative Dental Pain (0966-182)
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: MK0966, rofecoxib|DRUG: Comparator: oxycodone and acetaminophen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Expanded Allogeneic AD-MSCs in Patients With Moderate to Severe Psoriasis
Status: COMPLETED
Conditions: Mesenchymal Stromal Cells|Psoriasis|Drug Toxicity|Drug Effect
Interventions: BIOLOGICAL: adipose-derived multipotent mesenchymal stem cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Robot-Assisted Rehabilitation on Upper Extremity Functions in Chronic Stroke
Status: RECRUITING
Conditions: Stroke|Upper Extremity Paresis
Interventions: DEVICE: ReoGo|OTHER: Conventional Physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Systematic Study of Assessment of Attention-Deficit/Hyperactivity Disorder (ADHD)
Status: RECRUITING
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: PROCEDURE: Brief assessment protocol|PROCEDURE: Comprehensive assessment protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Role of Cytosorb in Left Ventricular Assist Device Implantation
Status: RECRUITING
Conditions: Heart Failure
Interventions: DEVICE: CytoSorb 300 mL device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ATRA and Carfilzomib in Plasma Cell Myeloma Patients
Status: RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: All-Trans Retinoic Acid (ATRA) Dose 0|DRUG: All-Trans Retinoic Acid (ATRA) Dose -1|DRUG: All-Trans Retinoic Acid (ATRA) Dose 1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Colistimethate Sodium for Injection in The Treatment of Carbapenem-Resistant Enterobacteriaceae Infection
Status: RECRUITING
Conditions: Carbapenem-Resistant Enterobacteriaceae Infection
Interventions: DRUG: treatment with or without colistin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Continuous Hemodialysis With an Enhanced Middle Molecule Clearance Membrane
Status: COMPLETED
Conditions: Septic Shock
Interventions: DEVICE: Dialyzer Ultraflux EMiC2|DEVICE: Dialyzer Ultraflux AV1000S
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Oral Motor Intervention to Preterms by Their Mothers
Status: NOT_YET_RECRUITING
Conditions: Premature
Interventions: OTHER: Intervention 1: Twice a day for 1 week PIOMI|OTHER: Intervention 2: Once a day for 2 weeks PIOMI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Investigate Skin Conditions and Patient Assessment of LAS 41002 in the Treatment of Atopic Eczema
Status: COMPLETED
Conditions: Atopic Eczema
Interventions: DRUG: LAS 41002|DRUG: Active
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Non-inferiority of PRO-122 Ophthalmic Solution vs KRYTANTEK Ofteno® in Glaucoma or Ocular Hypertension (CONFORTK)
Status: COMPLETED
Conditions: Primary Open Angle Glaucoma|Ocular Hypertension
Interventions: DRUG: PRO-122|DRUG: Krytantek Ofteno®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Post-market Clinical Follow-up Study of Reusable Clip Applier Cartridge Devices for LAParoscopic Surgery
Status: ACTIVE_NOT_RECRUITING
Conditions: Minimally Invasive Surgical Procedures|Laparoscopy|Leakage of Cardiac Device
Interventions: DEVICE: M/L-10 Multi-Fire Clip Applier and M/L-10 Clip Cartridge (Multi-Fire Clip System)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hyperbaric Oxygen Therapy and Insulin Resistance (HOTAIR2) - Effect of One HBO Session.
Status: COMPLETED
Conditions: Obesity|Type 2 Diabetes
Interventions: PROCEDURE: Hyperbaric Oxygen Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy of Intrathecal Clonidine Versus Neostigmine as Adjuvants to Bupivacaine on Postoperative Maternal and Fetal Outcomes After Elective Cesarean Section
Status: NOT_YET_RECRUITING
Conditions: Postoperative Pain
Interventions: DRUG: Clonidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: ADHD PreSMA Response Inhibition Therapy
Status: RECRUITING
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: DEVICE: Active repetitive TMS|DEVICE: Sham repetitive TMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect of Oral PhenazopyrIdine on Perioperative Voiding After Mid-urethral sliNg (EPIPhANy Study)
Status: COMPLETED
Conditions: Dysfunctional Voiding|Postoperative Pain
Interventions: DRUG: Phenazopyridine|OTHER: no Phenazopyridine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Maintaining Steady Albumin Levels (TAT 4) on Survival and Liver Related Complications in Cirrhosis With Ascites
Status: UNKNOWN
Conditions: Liver Cirrhosis
Interventions: DRUG: ALB Protein, Human|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Serum-Derived Bovine Immunoglobulin /Protein Isolate (SBI) 5.0 g Bid on Nutritional Status in Subjects With IBS-D
Status: COMPLETED
Conditions: Diarrhea-predominant Irritable Bowel Syndrome
Interventions: OTHER: Serum-derived bovine immunoglobulin protein isolate (SBI)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pharmacokinetics of Elinogrel in Healthy Volunteers and Patients With Mild, Moderate, and Severe Renal Impairment
Status: TERMINATED
Conditions: Renal Impairment
Interventions: DRUG: Elinogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Inflammatory Cell Trafficking After Myocardial Infarction
Status: WITHDRAWN
Conditions: Myocardial Infarction|Inflammation
Interventions: OTHER: Infusion of investigational product|OTHER: Cardiac magnetic resonance imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: RAGE-Control: Teaching Emotional Self-regulation Through Videogame Play
Status: UNKNOWN
Conditions: Anger|Aggression
Interventions: BEHAVIORAL: Relaxation training plus RAGE-Control|BEHAVIORAL: Relaxation training plus Sham Videogame
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility, Safety, and Outcomes of Intensive Enteral Nutrition in Patients With Mechanical Ventilation
Status: SUSPENDED
Conditions: Critical Illness
Interventions: OTHER: intensive enteral nutrition|OTHER: routine enteral nutrition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Urotherapy vs. Urotherapy With Constipation Treatment for Nocturnal Enuresis
Status: WITHDRAWN
Conditions: Nocturnal Enuresis
Interventions: DRUG: Polyethylene glycol 3350|BEHAVIORAL: Constipation behavioral therapy|BEHAVIORAL: Urotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Randomized OPTIMAL-ACT Trial
Status: COMPLETED
Conditions: Coronary Artery Disease|Ischemic Heart Disease|Anticoagulant-induced Bleeding|Coronary Syndrome
Interventions: DRUG: Unfractionated heparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Self-regulation of Prefrontal Cortex During Emotional Cognitive Control in PTSD
Status: WITHDRAWN
Conditions: PTSD|Cognitive Function
Interventions: OTHER: Real-time functional magnetic resonance neurofeedback (rtfMRI-nf)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Comparing the Use of a Mobile App for Surveillance of Adverse Events Following Influenza Immunization to a Web-Based Platform
Status: COMPLETED
Conditions: Mobile Apps|Immunization|Adverse Event Following Immunisation
Interventions: DEVICE: Mobile app - CanImmunize|DEVICE: Web based notification
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SCREENING
Clinical trial: BAC in Patient With Alzheimer's Disease or Vascular Dementia
Status: WITHDRAWN
Conditions: Alzheimer's Disease|Vascular Dementia
Interventions: DRUG: BAC|OTHER: BAC Matched Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neural Stem Cell Preserving Brain Radiation Therapy & Stereotactic Radiosurgery in Patients With 1-6 Brain Metastases
Status: TERMINATED
Conditions: Lung Cancer|Breast Cancer|Prostate Cancer
Interventions: RADIATION: Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Autonomic Neuropathy on the Efficacy of a DPP-IV Inhibitor (Galvus) Therapy
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: DRUG: Vildagliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of the Safety, Pharmacokinetics, and Therapeutic Activity of RO6958688 in Combination With Atezolizumab in Participants With Locally Advanced and/or Metastatic Carcinoembryonic Antigen (CEA)-Positive Solid Tumors
Status: COMPLETED
Conditions: Solid Tumors
Interventions: DRUG: Atezolizumab|DRUG: RO6958688
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ABC294640 in Treating Patients With Advanced Solid Tumors
Status: COMPLETED
Conditions: Pancreatic Cancer|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: sphingosine kinase-2 inhibitor ABC294640
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: YH4808 Postprandial PK/PD Study in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: YH4808|DRUG: YH4808|DRUG: YH4808|DRUG: YH4808
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pre-emptive Trans-cutaneous Versus Trans-oral Ultrasound Guided Peritonsillar Infiltration With Bupivacaine During Tonsillectomy
Status: UNKNOWN
Conditions: Postoperative Pain Management
Interventions: OTHER: trans-cutaneous ultrasound guided peritonsillar infiltration|OTHER: trans-oral ultrasound guided peritonsillar infiltration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Maxillary Arch Depth and Width in a Group of Surgically Repaired Unilateral Cleft Lip and Palate Children Versus Normal Children .
Status: UNKNOWN
Conditions: Cleft Lip and Palate
Interventions: OTHER: Alginate impressions , Photographic data and panoramic radiographs .
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of the Stinging Potential of Sunscreen Products in Human Eyes
Status: COMPLETED
Conditions: Sunscreen Agents
Interventions: DRUG: BAY98751 (Y65-110)|DRUG: BAY 98751 (Y65-102)|DRUG: BAY 98751 (Y65-106)|DRUG: Standard shampoo mixture (Control)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER