pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Air Stacking vs Glossopharyngeal Breathing in Neuromuscular Diseases
Status: COMPLETED
Conditions: Neuromuscular Diseases
Interventions: PROCEDURE: Glossopharyngeal Breathing|PROCEDURE: Air Stacking
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: r-hLIF for Improving Embryo Implantation in IVF
Status: COMPLETED
Conditions: Infertility Implantation Failure
Interventions: DRUG: Emfilermin, recombinant human leukemia inhibitory factor (r-hLIF)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: IV Acetaminophen in Children Undergoing Palatoplasty
Status: WITHDRAWN
Conditions: Cleft Palate
Interventions: DRUG: IV acetaminophen|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Adenocarcinoma of the Pancreas Treated With Panitumumab and Gemcitabine Regimen to Investigate Overall Survival as Primary Endpoint
Status: TERMINATED
Conditions: Cancer of Pancreas|Cancer of the Pancreas|Pancreas Cancer|Pancreatic Cancer
Interventions: DRUG: Gemcitabine|DRUG: panitumumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neurofeedback for Tinnitus - Does Frequency Specificity Matter?
Status: COMPLETED
Conditions: Tinnitus|Subjective Tinnitus|Chronic Tinnitus
Interventions: BEHAVIORAL: alpha/delta neurofeedback|BEHAVIORAL: beta/theta neurofeedback|OTHER: Diary completion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Efficacy of a Video Based Intervention to Educate Teen Moms About Fetal Alcohol Syndrome (FAS)
Status: TERMINATED
Conditions: Fetal Alcohol Syndrome|Teen Pregnancy
Interventions: OTHER: An educational video about Fetal Alcohol Syndrome
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Assessing Efficacy and Safety of Lacosamide Compared to Placebo in Reducing Signs and Symptoms of Fibromyalgia Syndrome.
Status: COMPLETED
Conditions: Fibromyalgia Syndrome
Interventions: DRUG: Lacosamide|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: BIOCLEAN MPS (Multi-Purpose Solution) VII in Combination With Biofinity Lens: A Two Week Crossover Study
Status: COMPLETED
Conditions: Myopia
Interventions: DEVICE: Bioclean MPS VII|DEVICE: Aosept Clearcare|DEVICE: comfilcon A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Evaluation of Fecal Microbiota Transplantation in Severe Alcoholic Hepatitis
Status: RECRUITING
Conditions: Alcoholic Hepatitis
Interventions: BIOLOGICAL: Fecal Microbiota Transplantation|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: An Eighteen Month Efficacy and Safety Study in Obese Patients (0364-020)(COMPLETED)
Status: COMPLETED
Conditions: Obesity and Obesity-related Medical Conditions
Interventions: DRUG: taranabant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Two Olaparib Tablets in Patients With Cancers
Status: COMPLETED
Conditions: Neoplasms
Interventions: DRUG: The test olaparib tablet (T)|DRUG: The reference olaparib tablet (R)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Application of Thoracic Epidural Analgesia in Patients With Acute Pancreatitis
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Pancreatitis
Interventions: PROCEDURE: Thoracic Epidural Analgesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rigorous Assessment of P. Vivax Relapses and Primaquine Efficacy for Radical Cure
Status: RECRUITING
Conditions: Vivax Malaria
Interventions: DRUG: Primaquine|DRUG: Artesunate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Peripheral Nerve Blocks in Pediatric Orthopedic Patients
Status: TERMINATED
Conditions: Pediatric Extremity Fracture|Pediatric Extremity Soft Tissue Injury
Interventions: PROCEDURE: Regional block|PROCEDURE: General Anesthesia|DRUG: Local Anesthetic Ropivacaine|DRUG: Opioids Morphine|DRUG: Oral pain medication Acetaminophen with Hydrocodone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Cortical Excitability and Inhibition in MDD
Status: COMPLETED
Conditions: Major Depressive Disorder, Recurrent, Mild|Depressive Disorder, Major
Interventions: DEVICE: Transcranial Magnetic Stimulation (TMS)|DEVICE: Magnetic Resonance Spectroscopy and Imaging
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of the Effect of Etoricoxib and Diclofenac on Early Morning Activity in Rheumatoid Arthritis (RA)
Status: WITHDRAWN
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Etoricoxib|DRUG: Diclofenac
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Analysis of the Genotype/Phenotype Relationship in the Fuchs' Corneal Endothelial Dystrophy in France.
Status: COMPLETED
Conditions: Fuchs Endothelial Corneal Dystrophy
Interventions: OTHER: Collection of datas|BIOLOGICAL: blood sample|OTHER: slit lamp examination
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety Study of JNJ-32729463 for Treating Complicated Skin and Skin Structure Infections Compared to Linezolid (Zyvox)
Status: COMPLETED
Conditions: Complicated Skin and Skin Structure Infections
Interventions: DRUG: JNJ-32729463|DRUG: linezolid|DRUG: JNJ-32729463 placebo|DRUG: linezolid placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CR6086/AGEN2034 Combination in Stage IV pMMR - MSS CRC, and Other Metastatic GI Cancers
Status: RECRUITING
Conditions: Refractory Metastatic Colorectal Cancer|Solid Tumor|Metastatic Microsatellite-stable Colorectal Cancer|Mismatch Repair Protein Proficient|Metastatic GI Cancers|Gastric Cancer
Interventions: DRUG: CR6086|BIOLOGICAL: AGEN2034
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Absorption, Metabolism, and Excretion and Estimation of the Absolute Bioavailability of K-312
Status: COMPLETED
Conditions: Dyslipidemia
Interventions: DRUG: K-312 100 mg|DRUG: K-312 100 ug C14 IV
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: L-DOPA vs. Placebo for Depression and Psychomotor Slowing in Older Adults
Status: TERMINATED
Conditions: Major Depressive Disorder|Dysthymia|Depression
Interventions: DRUG: L-DOPA|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Topical Cyclosporine Suspension for the Treatment of Brittle Nails
Status: COMPLETED
Conditions: Brittle Nail Syndrome
Interventions: DRUG: topical cyclosporine ophthalmic suspension 0.05%|DRUG: vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Dexmedetomidine on Respiratory Mechanics and Oxygenation During One Lung Ventilation With Chronic Obstructive Lung Disease
Status: COMPLETED
Conditions: COPD, One Lung Ventilation
Interventions: DRUG: saline infusion|DRUG: dexmedetomidine infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose:
Clinical trial: ZOSTAVAX™ Administered Concomitantly With PNEUMOVAX™ 23 (V211-012)(COMPLETED)
Status: COMPLETED
Conditions: Herpes Zoster|Pneumococcal Infection
Interventions: BIOLOGICAL: Zoster Vaccine, Live, (Oka-Merck), ZOSTAVAX™|BIOLOGICAL: Comparator: placebo (concomitant-vaccine matched)|BIOLOGICAL: Pneumococcal Vaccine, Polyvalent (23-valent), PNEUMOVAX™ 23
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of LY3303560 in Healthy Participants and Participants With Alzheimer's Disease (AD)
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: LY3303560 - IV|DRUG: Saline Solution - IV|DRUG: LY3303560 - SC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Postprandial VLDL-triglyceride Metabolism in Type 2 Diabetes Patients With and Without NAFLD
Status: COMPLETED
Conditions: NAFLD|Type 2 Diabetes
Interventions: DIETARY_SUPPLEMENT: High-fat mixed-meal tolerance test (HF-MMTT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Correlation Between Changes in Lung Function and Changes in Cough and Dyspnoea in Nintedanib-treated Connective Tissue Disease Interstitial Lung Disease (CTD-ILD) Patients
Status: RECRUITING
Conditions: Lung Diseases, Interstitial
Interventions: DRUG: Nintedanib
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Probucol Combined With Valsartan in Reducing Proteinuria in Diabetes Nephropathy
Status: UNKNOWN
Conditions: Type 2 Diabetes Mellitus|Nephropathy
Interventions: DRUG: Valsartan|DRUG: Placebo|DRUG: Probucol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bovine Pericardial Patch and TiLOOP® Bra Mesh in Immediate Implant Breast Reconstruction.
Status: UNKNOWN
Conditions: Implant Breast Reconstruction|TiLOOP® Bra Mesh|Bovine Pericardial Patch
Interventions: PROCEDURE: Bovine Pericardial Patch in Immediate Implant Breast Reconstruction|PROCEDURE: TiLOOP® Bra Mesh in Immediate Implant Breast Reconstruction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Online Transdiagnostic Intervention for Emotional Disorders and Stress-related Disorders
Status: UNKNOWN
Conditions: Emotional Disorder|Stress Related Disorder|Anxiety Disorders|Depression
Interventions: BEHAVIORAL: Transdiagnostic online intervention|BEHAVIORAL: TCC online intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Use of Glutamic Acid Decarboxylase (GAD) and Gamma-Amino Butyric Acid (GABA) in the Treatment of Type I Diabetes
Status: COMPLETED
Conditions: Type I Diabetes
Interventions: DRUG: Placebo GABA and Placebo GAD-alum|DRUG: GABA and Placebo GAD-alum|DRUG: Active Oral GABA and Active GAD-alum injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The TRANQUILITY 2 Trial: A Phase 3 Clinical Trial to Assess the Efficacy and Safety in Subjects With Dry Eye Disease
Status: COMPLETED
Conditions: Dry Eye
Interventions: DRUG: Reproxalap Ophthalmic Solution (0.25%)|DRUG: Vehicle Ophthalmic Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Photobiomodulation In the Masseter and Temporal In Patients With Temporomandibular Joint Dysfunction
Status: COMPLETED
Conditions: Temporomandibular Disorder
Interventions: OTHER: phototherapy|OTHER: phototherapy placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: PfSPZ Vaccine Trial in Malian Children
Status: COMPLETED
Conditions: Malaria|Malaria,Falciparum
Interventions: BIOLOGICAL: Sanaria® PfSPZ Vaccine|OTHER: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: R21 India Pal-Care Evaluation
Status: UNKNOWN
Conditions: Cancer Palliative Care
Interventions: BEHAVIORAL: Pal-Care|BEHAVIORAL: Control-Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: London Asthma Diagnostics Study
Status: NOT_YET_RECRUITING
Conditions: Asthma
Interventions: DIAGNOSTIC_TEST: Oscillometry with reversibility testing|DIAGNOSTIC_TEST: Breath volatile testing|DIAGNOSTIC_TEST: Nasal eosinophil peroxidase|DIAGNOSTIC_TEST: Handheld capnometry
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Sleep, Hypertension, and Nocturia: a Multicomponent Approach for Comorbid Illnesses
Status: COMPLETED
Conditions: Nocturia|Hypertension|Sleep Disturbance
Interventions: BEHAVIORAL: BBTI|OTHER: PM antihypertensive dosing or Chronotherapy|OTHER: AM antihypertensive dosing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Immunisation, Treatment and Controlled Human Hookworm Infection
Status: COMPLETED
Conditions: Necator Americanus Infection
Interventions: BIOLOGICAL: 3x 50 L3 larvae immunisation with albendazole treatment|OTHER: 3x placebo immunisation with albendazole treatment|BIOLOGICAL: 2x 50 L3 larvae infection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Clinical and Kinematic Assessment for Determination of Botox® Injection Parameters in Cervical Dystonia
Status: UNKNOWN
Conditions: Cervical Dystonia
Interventions: DRUG: Botulinum Toxin Type A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Platelet Rich Plasma (PRP) on Healing Time in Patients Following Pilonidal Sinus Surgery
Status: COMPLETED
Conditions: Pilonidal Disease|Pilonidal Sinus
Interventions: OTHER: Platelet rich plasma
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Effect of Shock Wave In Reducing Chemotherapy- Induced Peripheral Neuropathy In Adult and Pediatric Tumors Patients
Status: UNKNOWN
Conditions: Peripheral Neuropathy
Interventions: DEVICE: The Shock wave Therapy.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Autologous Stem Cell Transplant for Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: OTHER: immuno-ablation and autologous CD34 selected hematopoietic stem cell transplantation (HSCT),|OTHER: Standard Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of a Combined mHealth-CBT Psychological Intervention to Improve Psychological Well-Being in Young Patients With T1D
Status: ACTIVE_NOT_RECRUITING
Conditions: Diabetes Mellitus, Type 1
Interventions: BEHAVIORAL: Cognitive-Behavioral Therapy: face-to-face + app
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Conventional Endoscopic Mucosal Resection Versus Cold Snare Endoscopic Mucosal Resection of Colonic Lateral Spreading Lesions - A Randomised Controlled Trial
Status: COMPLETED
Conditions: Adenoma Colon|Colon Adenoma|Colon Cancer
Interventions: PROCEDURE: Conventional Endoscopic Mucosal Resection|PROCEDURE: Cold Snare Endoscopic Mucosal Resection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase IIa Withdrawal Study of CNV1014802 in Patients With Trigeminal Neuralgia
Status: COMPLETED
Conditions: Trigeminal Neuralgia
Interventions: DRUG: CNV1014802|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Study of HRS8807 Monotherapy and in Combination With SHR6390 in Subjects With ER-Positive, HER2-Negative Metastatic or Locally Advanced Breast Cancer
Status: RECRUITING
Conditions: ER-Positive, HER2-Negative Breast Cancer
Interventions: DRUG: HRS8807|DRUG: HRS8807|DEVICE: HRS8807、SHR6390|DRUG: HRS8807、SHR6390
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Therapeutic Usability of RESPIRA ADVANCED Device in Patients Under Invasive Mechanical Ventilation
Status: UNKNOWN
Conditions: Respiratory Insufficiency
Interventions: DEVICE: RESPIRA device.com® Advanced
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment Period and Long-term Effect of Functional Electric Stimulation (FES) for Bruxism
Status: TERMINATED
Conditions: Bruxism
Interventions: DEVICE: Grindcare (Active)|DEVICE: Grindcare (Placebo - the device is not activated)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Optimizing Outcomes With Physical Therapy Treatment for IndividuALs Surviving an ICU Admission for Covid-19
Status: COMPLETED
Conditions: Covid-19|Critical Illness|Post Intensive Care Unit Syndrome|Muscle Weakness
Interventions: OTHER: ICU Recovery + Physical Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Permethrin-treated Baby-wraps for the Prevention of Malaria in Children
Status: ACTIVE_NOT_RECRUITING
Conditions: Malaria|P. Falciparum
Interventions: OTHER: Permethrin-treated lesu|OTHER: Untreated lesu
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Different Anesthesia Methods on Development of Postnatal Depression After Cesarean Delivery
Status: COMPLETED
Conditions: Pregnancy Related
Interventions: OTHER: Grup I= General anesthesia group|OTHER: Grup II= Spinal anesthesia group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Real World Research: Comparison of Precision and Experience Therapy for Hypertension, Diabetes or Hyperlipidemias
Status: ACTIVE_NOT_RECRUITING
Conditions: Hypertension,Essential|Diabetes type2|Hyperlipidemias
Interventions: DIAGNOSTIC_TEST: Gene detection of therapeutic drugs for chronic cardiovascular and cerebrovascular diseases|BEHAVIORAL: Regular follow-up and patient education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Learn How Safe Starting Vericiguat at a Dose of 5 Milligrams is in Participants With Chronic Heart Failure With Reduced Ejection Fraction
Status: COMPLETED
Conditions: Chronic Heart Failure With Reduced Ejection Fraction
Interventions: DRUG: Vericiguat (BAY1021189) 5 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Interactions Between Buprenorphine and Tipranavir/Ritonavir
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Buprenorphine, Tipranavir and ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of Diagnostic Biomarkers of Acute Acoustic Trauma
Status: RECRUITING
Conditions: Acoustic Trauma
Interventions: OTHER: Hearing test|OTHER: Questionnaire about previous noise exposure|OTHER: Otoacoustic emission measurement|OTHER: Electrocochleography|OTHER: Speech audiometry in noise|OTHER: Multi-frequency impedance measurement|OTHER: Assessment of tinnitus severity|BIOLOGICAL: Blood sample collection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Four Way Crossover Closed Loop With Exercise Detection
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: DEVICE: Artificial Pancreas Controller in Dual Hormone Mode|DEVICE: Subject's insulin pump|DEVICE: Artificial Pancreas Controller in Single Hormone Mode|DEVICE: Artificial Pancreas Controller in Predictive Low Glucose Suspend Mode
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Social Reward and Its Effect on Brain Functions in Psychotherapies for Mid- and Late-Life Depression
Status: RECRUITING
Conditions: Major Depressive Disorder
Interventions: BEHAVIORAL: "Engage & Connect" Psychotherapy|BEHAVIORAL: Symptom Review and Psychoeducation (SRP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Surgical Appendiceal Stump Closure - a Comparison Between Surgical Appendiceal Base Closure Methods, and Appendiceal Stump Complications.
Status: COMPLETED
Conditions: All Appendectomies Performed During the Designated Period in Single Medical Center
Interventions: PROCEDURE: laparoscopic appendectomy using a single endoloop for appendiceal stump closure|PROCEDURE: laparoscopic appendectomy using two endoloops for appendiceal stump closure|PROCEDURE: laparoscopic appendectomy using a clip for appendiceal stump closure
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: MAPS & ITEC Cohorts: 6-8 Years Follow-up
Status: COMPLETED
Conditions: Immunotherapy|Allergy and Immunology|Asthma
Interventions: DRUG: House dust-mite SLIT|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Aspirin Resistance and Sleep Apnea in Type-2 Diabetic Patients
Status: TERMINATED
Conditions: Atherothrombosis|Type 2 Diabetes|Obstructive Sleep Apnea Syndrome
Interventions: DEVICE: CPAP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Music Therapy for Rehabilitation in Post-stroke Non-fluent Aphasia: the Indian Adaptation
Status: NOT_YET_RECRUITING
Conditions: Stroke Rehabilitation|Aphasia, Broca
Interventions: OTHER: Speech rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Integrated Primary Care for Chronic Lung Disease: PACK Brazil
Status: UNKNOWN
Conditions: Asthma|Chronic Obstructive Pulmonary Disease
Interventions: BEHAVIORAL: Outreach education training|BEHAVIORAL: No outreach education training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Evaluation of the Effectiveness of Dry Needling Versus Foam Roller
Status: COMPLETED
Conditions: Myofascial Pain Syndromes|Dry Needling
Interventions: PROCEDURE: Dry needling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Longitudinal Assessment of Gut Hormone Secretion Following Upper Gastrointestinal Surgery for Cancer
Status: COMPLETED
Conditions: Esophageal Neoplasms|Stomach Neoplasms|Weight Loss|Malnutrition
Interventions: OTHER: Standardized 400kcal semi-liquid meal
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Non-inferiority Randomized Controlled Trial to Evaluate Promoting Condom Use Among MSM and Transgender Individuals in China
Status: COMPLETED
Conditions: Human Immunodeficiency Virus|Sexually Transmitted Diseases
Interventions: BEHAVIORAL: crowdsourced video|BEHAVIORAL: social marketing video
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Safety and Efficacy of PRX-102 in Patients With Fabry Disease Currently Treated With REPLAGAL® (Agalsidase Alfa)
Status: COMPLETED
Conditions: Fabry Disease
Interventions: BIOLOGICAL: PRX-102 (pegunigalsidase alfa)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Study of MEDI4736 Monotherapy in Treatment of Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck
Status: COMPLETED
Conditions: Recurrent or Metastatic PD-L1-positive Squamous Cell Carcinoma of the Head and Neck
Interventions: DRUG: MEDI4736
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A 6 Month Safety Study Comparing Symbicort With Inhaled Corticosteroid Only in Asthmatic Adults and Adolescents
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Symbicort pMDI|DRUG: budesonide pMDI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Zevalin/BEAM/Rituximab vs BEAM/Rituximab With or Without Rituximab in Autologous Stem Cell Transplantation
Status: COMPLETED
Conditions: Diffuse Large Cell Lymphoma|Lymphoma
Interventions: DRUG: Zevalin|DRUG: Carmustine|DRUG: Etoposide|DRUG: Cytarabine|DRUG: Melphalan|DRUG: Rituximab|PROCEDURE: Stem Cell Transplant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of TOA Versus PNF Techniques on Trunk Control in Children With Hemiplegic Cerebral Palsy
Status: COMPLETED
Conditions: Hemiplegic Cerebral Palsy
Interventions: DEVICE: Group A|DEVICE: Group B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare Efficacy and Safety of Trifarotene Cream When Used With an Oral Antibiotic for the Treatment of Severe Acne Vulgaris (AV)
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: Trifarotene cream|DRUG: Doxycycline hyclate|DRUG: Trifarotene Vehicle|DRUG: Doxycycline Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: NTLA-2002 in Adults With Hereditary Angioedema (HAE)
Status: ACTIVE_NOT_RECRUITING
Conditions: Hereditary Angioedema
Interventions: BIOLOGICAL: Biological NTLA-2002|OTHER: Normal Saline IV Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Use of ıntegrated Pulmonary Index Monitorisation in Children Undergoing Botulinum Toxin Injection
Status: RECRUITING
Conditions: Cerebral Palsy|Pediatric ALL
Interventions: DEVICE: integrated pulmonary index|DEVICE: saturation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: The Clinical Applicability of the 'TIB' Olfactory Test Device
Status: COMPLETED
Conditions: Anosmia|Hyposmia
Interventions: DIAGNOSTIC_TEST: 'TIB' Olfactory Test|DIAGNOSTIC_TEST: Traditional Chinese version of the University of Pennsylvania of Smell Identification Test (UPSIT-TC)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Adding Urea to the Final Dialysis Fluid
Status: NOT_YET_RECRUITING
Conditions: Dysequilibrium Syndrome|ESRD|Hyperkalemia|Metabolic Acidosis
Interventions: DRUG: Urea in the dialysate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Of Patients With Allergic Rhinitis And Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: fluticasone propionate/salmeterol|DRUG: fluticasone propionate|DRUG: montelukast
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Rapid On-site Cytopathologic Evaluation in the Diagnosis of Hilar/Mediastinal Adenopathy
Status: COMPLETED
Conditions: Lung Cancer|Sarcoidosis|Tuberculosis
Interventions: PROCEDURE: Rapid on-site cytopathologic evaluation (ROSE)|PROCEDURE: TBNA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Dentoskeletal Changes Expansion Using Invisalign Versus Conventional Expander
Status: NOT_YET_RECRUITING
Conditions: Expansion of Maxillary Arch|Maxillary Hypoplasia
Interventions: DEVICE: Invisalign|DEVICE: Conventional expander
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acupuncture for Oxaliplatin-induced Peripheral Neuropathy in Gastro-intestinal Cancer Patients
Status: RECRUITING
Conditions: Colorectal Cancer|Liver Cancer|Gastric Cancer|Pancreas Cancer|Esophagus Cancer
Interventions: OTHER: Acupuncture intervention|OTHER: No acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Peripheral Electrical Stimulation (PES) on Brain Response to Glucose Stimuli
Status: UNKNOWN
Conditions: Brain Activity|Glucose Control
Interventions: DEVICE: Stimulator|DIETARY_SUPPLEMENT: Glucose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Brief Cognitive Behavioral Therapy for People With Physical Disabilities
Status: RECRUITING
Conditions: Suicide|Suicide, Attempted|Suicidal Ideation|Disability Physical|Disability Hearing|Disability, Vision
Interventions: BEHAVIORAL: Brief Cognitive Behavioral Therapy for People with Physical Disabilities
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Researching the Effectiveness of Attexis, a Digital Health Application for Adults With Attention Deficit Hyperactivity Disorder
Status: ACTIVE_NOT_RECRUITING
Conditions: Adult Attention Deficit Hyperactivity Disorder
Interventions: BEHAVIORAL: attexis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Using Eculizumab in Transfusion Dependent Paroxysmal Nocturnal Hemoglobinuria (PNH) Patients
Status: COMPLETED
Conditions: Hemoglobinuria, Paroxysmal
Interventions: DRUG: eculizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: ECT
Clinical trial: tDCS Associated With Locomotor Training on Functional Mobility of Cerebellar Ataxia
Status: ACTIVE_NOT_RECRUITING
Conditions: Ataxia, Cerebellar
Interventions: DEVICE: Cerebellar transcranial direct current stimulation|OTHER: Treadmill locomotor training|DEVICE: Sham Cerebellar transcranial direct current stimulation|DEVICE: Cerebello-spinal direct current stimulation|DEVICE: Sham cerebello-spinal direct current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Efficacy of MEDI8897 for the Prevention of Medically Attended RSV LRTI in Healthy Preterm Infants.
Status: COMPLETED
Conditions: Respiratory Syncytial Virus Infections
Interventions: DRUG: MEDI8897|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Treatment of Osteoarthrosis of the Knee With Platelet Rich Plasma, Comparative Study With Hyaluronic Acid
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: BIOLOGICAL: Platelet Rich Plasma|DRUG: Hyaluronic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prazosin for Treating Noncombat Trauma Post-Traumatic Stress Disorder
Status: TERMINATED
Conditions: Post-Traumatic Stress Disorder|Sleep Initiation and Maintenance Disorders
Interventions: DRUG: Prazosin|DRUG: Placebo|BEHAVIORAL: Psychotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CoQun Study - (COQUN): a Study to Evaluate the Effects of CoQun in Patients Affected by Open-angle Glaucoma
Status: TERMINATED
Conditions: Open Angle Glaucoma
Interventions: DEVICE: Coqun® ophthalmic solution|OTHER: Placebo ophthalmic solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: The Effect of End-of-Life Care Awareness Education on Knowledge, Attitudes, and Behaviors of Intensive Care Nurses: A Randomized Controlled Study
Status: ACTIVE_NOT_RECRUITING
Conditions: End-of-life Care
Interventions: OTHER: End-of-life care awareness training in intensive care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: CAR-T for R/R B-NHL
Status: UNKNOWN
Conditions: Relapsed Non Hodgkin Lymphoma|Refractory Non-Hodgkin Lymphoma|CAR - T CD19/CD20/CD22/CD30
Interventions: BIOLOGICAL: CAR-T
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Effectiveness of Pulmonary Vein isOLation And posterioR Wall Ablation wIth pulSed Field Energy in Patients With Paroxysmal and Persistent AF
Status: RECRUITING
Conditions: Atrial Fibrillation
Interventions: DEVICE: Pulsed Field Ablation (PFA)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Tislelizumab With Afatinib for Resectable Head and Neck Squamous Cell Carcinoma
Status: RECRUITING
Conditions: Head and Neck Cancer
Interventions: BIOLOGICAL: Tislelizumab|DRUG: Afatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of AD-203
Status: COMPLETED
Conditions: Acute Gastritis|Chronic Gastritis
Interventions: DRUG: AD-203|DRUG: Mucosta tab.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: SGN-00101 Vaccine in Treating Human Papillomavirus in Patients Who Have Abnormal Cervical Cells
Status: COMPLETED
Conditions: Atypical Squamous Cells of Undetermined Significance|Cervical Cancer|High-grade Squamous Intraepithelial Lesion|Low-grade Squamous Intraepithelial Lesion
Interventions: BIOLOGICAL: HspE7|OTHER: placebo|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effectiveness of TheRApeutic ExercIse aNd EDucation on Patients With Massive Rotator Cuff Tears
Status: RECRUITING
Conditions: Rotator Cuff Injuries
Interventions: OTHER: Therapeutic resistance exercise|OTHER: Education
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Serratus Plane Block in Preventing Postoperative Pain of Mastectomy
Status: COMPLETED
Conditions: Serratus Plane Block|Chronic Pain|Breast Cancer
Interventions: PROCEDURE: serratus plane block with local anesthetic|PROCEDURE: serratus plane block with saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Day-case or Inpatient Care Following Inguinal Hernia Repair in Elderly Patients
Status: COMPLETED
Conditions: Hernia, Inguinal
Interventions: OTHER: day surgery group|OTHER: inpatient group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study of the Treatment of Eosinophilic Esophagitis With Omalizumab
Status: COMPLETED
Conditions: Esophagitis
Interventions: DRUG: omalizumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Transdermal Fentanyl Patch for Postoperative Analgesia After Abdominal Surgery: a Randomized Placebo-controlled Trial
Status: COMPLETED
Conditions: Postoperative Pain Relief
Interventions: DRUG: transdermal fentanyl patch (50 mcg/hour)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immunoadsorption Versus High-dose Intravenous Corticosteroids in Relapsing Multiple Sclerosis
Status: UNKNOWN
Conditions: Multiple Sclerosis, Relapsing-Remitting
Interventions: DRUG: Methyl Prednisolonate|PROCEDURE: Immunoadsorption
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Systemic Lidocaine Infusion to Postoperative Pain and Quality of Recovery After Laparoscopic Hernia Repair in Children
Status: COMPLETED
Conditions: Inguinal Hernia
Interventions: DRUG: Systemic intravenous lidocaine infusion|DRUG: Normal saline infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Investigate the Efficacy and Safety of Bendamustine Compared With Bendamustine+Obinutuzumab (GA101) in Participants With Rituximab-Refractory, Indolent Non-Hodgkin's Lymphoma (GADOLIN)
Status: COMPLETED
Conditions: Non-Hodgkin's Lymphoma
Interventions: DRUG: Obinutuzumab|DRUG: Bendamustine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of a Glargine-based Hospital Discharge Algorithm in Coronary Artery Bypass Graft (CABG) Patients
Status: COMPLETED
Conditions: Poor Glycemic Control
Interventions: DRUG: Metformin|DRUG: Glargine insulin|DRUG: Glulisine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Use of Magnetic Endoscopic Imaging for Improving Quality Indicators in Outpatient Colonoscopy
Status: COMPLETED
Conditions: Colonoscopy
Interventions: DEVICE: Magnetic Endoscopic Imaging (MEI) colonoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: [11C]-PBR28 Positron Emission Tomography Study to Evaluate the Effect of ABT 555 in Subjects With Relapsing Forms of Multiple Sclerosis
Status: TERMINATED
Conditions: Multiple Sclerosis
Interventions: DRUG: ABT-555
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Culturally Tailored ACT for Black Trauma
Status: WITHDRAWN
Conditions: Stress Disorders, Traumatic|Anxiety|Anxiety Disorders
Interventions: BEHAVIORAL: POOF ACT program|BEHAVIORAL: Classic ACT program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Study on the Influence of Dyadic Psychoeducational Intervention on Patients With Maintenance Hemodialysis
Status: RECRUITING
Conditions: End Stage Renal Disease on Dialysis
Interventions: BEHAVIORAL: dyadic psychological intervention strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Compare Effectiveness of Diuretics in Hemodialysis Patients With Residual Renal Function
Status: UNKNOWN
Conditions: Chronic Kidney Insufficiency|Hemodialysis Treatment|Diuresis Preserved
Interventions: DRUG: Hydrochlorothiazide and furosemide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Avastin (Bevacizumab) and Xeloda (Capecitabine) in Patients With Advanced or Metastatic Liver Cancer
Status: COMPLETED
Conditions: Liver Cancer
Interventions: DRUG: bevacizumab [Avastin]|DRUG: capecitabine [Xeloda]
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of LY2886721 in Mild Cognitive Impairment Due to Alzheimer's Disease or Mild Alzheimer's Disease
Status: TERMINATED
Conditions: Alzheimer's Disease
Interventions: DRUG: LY2886721|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Remote Ischemic Conditioning With Novel Optical Sensor Feedback Device in Acute Ischemic Stroke
Status: COMPLETED
Conditions: Stroke, Acute Ischemic|Small Vessel Cerebrovascular Disease
Interventions: DEVICE: Remote Ischemic Conditioning with Novel Optical Sensor Feedback Device|DEVICE: Sham Remote Ischemic Conditioning with Novel Optical Sensor Feedback Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Confirmation Study of Eribulin in Combination With Capecitabine
Status: COMPLETED
Conditions: Metastatic Breast Cancer
Interventions: DRUG: Eribulin mesylate|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exploratory Study of Respiratory Bacterial Infections or Superinfections and Colonizations in Patients With Spinal Muscular Atrophy Under NIV
Status: RECRUITING
Conditions: Non Invasive Ventilation|Spinal Muscular Atrophy|Respiratory Bacterial Infection
Interventions: OTHER: non invasive ventilation samples|OTHER: patient samples|OTHER: parent questionnaire
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: EMA/EMI for Psychiatrically Hospitalized Emerging Adults Who Drink to Cope
Status: RECRUITING
Conditions: Alcohol Use Disorder
Interventions: BEHAVIORAL: Personalized Normative Feedback|BEHAVIORAL: Coping-Motive Specific Personalized Feedback Intervention plus an Ecological Momentary Intervention (PFIcope+EMI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pyruvic Acid Versus Salicylic Acid Preparation in Treatment of Plantar Warts
Status: UNKNOWN
Conditions: Plantar Wart
Interventions: DRUG: Pyruvic acid|DRUG: Salicylic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Thalidomide in Combination With Temodar in Patients With Neuroendocrine Tumors
Status: COMPLETED
Conditions: Neuroendocrine Tumor
Interventions: DRUG: Thalidomide|DRUG: Temodar
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Metabolic Effects of Different Weight Loss Diets
Status: COMPLETED
Conditions: Metabolic Syndrome X|Obesity|Insulin Resistance|Hypertension|Diabetes
Interventions: BEHAVIORAL: The DASH diet|BEHAVIORAL: The low glycemic Index Diet|BEHAVIORAL: Reduced calorie American Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Trial of the FreeAspire Versus PEP-bottle After Acute Exacerbation in COPD Patients
Status: COMPLETED
Conditions: COPD
Interventions: DEVICE: standard treatment|DEVICE: Free Aspire
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT