pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: NASPI: N-Acetylcysteine vs. Ascorbic Acid for Prevention of Contrast Induced Nephropathy in Renal Insufficiency Undergoing Coronary Catheterization
Status: COMPLETED
Conditions: Kidney Failure
Interventions: DRUG: N-acetylcystein|DRUG: ascorbic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Correlation Between Serum Uric Acid and Pulmonary Hypertension in Obstructive Sleep Apnea Syndrome
Status: COMPLETED
Conditions: Obstructive Sleep Apnea
Interventions: DIAGNOSTIC_TEST: polysomnography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Mitigating Toxicity by Electronic Health Portal-mediated Interactive Monitoring of Patient-reported Side Effects
Status: NOT_YET_RECRUITING
Conditions: Breast Cancer|eHealth|Symptom Monitoring|Self Management
Interventions: OTHER: eChemoCoach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of Serum Folate Levels in Patients Treated With Olaparib
Status: ACTIVE_NOT_RECRUITING
Conditions: Ovarian Cancer|Breast Cancer|Folic Acid Deficiency
Interventions: DRUG: Folic Acid Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 0.15 mg Spinal Morphine vs. no Treatment for Morphine Requirement After VATs.
Status: UNKNOWN
Conditions: Postoperative Pain
Interventions: DRUG: Spinal morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Safety and Efficacy of Risperidone as Adjunctive Therapy to Mood Stabilizers in the Long-term Treatment of Bipolar Mania
Status: COMPLETED
Conditions: Bipolar Disorder
Interventions: DRUG: risperidone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of BI-1206 in Combination With Pembrolizumab in Subjects With Advanced Solid Tumors (KEYNOTE-A04)
Status: RECRUITING
Conditions: Solid Tumor, Adult
Interventions: DRUG: BI1206
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Femoral Triangle and Adductor Canal Blocks Versus Femoral Nerve Block for Total Knee Arthroplasty
Status: COMPLETED
Conditions: Total Knee Arthroplasty
Interventions: PROCEDURE: Femoral Nerve Block|PROCEDURE: Femoral Triangle & Adductor Canal Blocks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study in Healthy Men to Test How Different Doses of BI 474121 Are Taken up and How They Influence the Amount of a Molecular Messenger (cGMP) in the Spinal Fluid
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Placebo|DRUG: 2.5 milligram (mg) BI 474121|DRUG: 10 milligram (mg) BI 474121|DRUG: 20 milligram (mg) BI 474121|DRUG: 40 milligram (mg) BI 474121
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Combined Use of Etomidate and Propofol in Painless Gastroscopy.
Status: UNKNOWN
Conditions: Safety of Gastroscopy
Interventions: DRUG: Fentanyl Injection|DRUG: Etomidate Fat Emulsion Injection|DRUG: Propofol Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety and Efficacy of Pembrolizumab (MK-3475) Plus Binimetinib Alone or Pembrolizumab Plus Chemotherapy With or Without Binimetinib in Metastatic Colorectal Cancer (mCRC) Participants (MK-3475-651)
Status: COMPLETED
Conditions: Metastatic Colorectal Cancer
Interventions: BIOLOGICAL: Pembrolizumab|DRUG: Binimetinib|DRUG: Oxaliplatin|DRUG: Leucovorin|DRUG: 5-Fluorouracil [5-FU]|DRUG: Irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of VIP152, Venetoclax, and Prednisone (VVIP) in Relapsed/Refractory Lymphoid Malignancies
Status: RECRUITING
Conditions: Lymphoma|Non-Hodgkin Lymphoma|NHL|Hematologic Malignancies|Lymphoid Malignancies
Interventions: DEVICE: Vysis LSI MYC Break Apart Rearrangement Probe Kit|DRUG: venetoclax|DRUG: VIP152|DRUG: prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TB-CAPT CORE Truenat Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Tuberculosis|Diagnoses Disease
Interventions: DIAGNOSTIC_TEST: Truenat TB platform/TB assays
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Oral Tissue Tolerance of a Mouthrinse
Status: COMPLETED
Conditions: Dental Health
Interventions: DEVICE: Potassium Oxylate Mouthwash|DRUG: Sodium Fluoride Dentifrice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Injectable Poly-L-Lactic Acid for Volumization and Adipogenesis of the Hip Dell
Status: UNKNOWN
Conditions: Skin Laxity
Interventions: DEVICE: injectable poly-L-lactic acid|OTHER: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Assessment of Botulax® and BOTOX® for Improvement of Glabellar Lines.
Status: COMPLETED
Conditions: Glabellar Lines
Interventions: DRUG: Botulinum Toxin A type for injection (Botulax®)|DRUG: Botulinum Toxin A type for injection (BOTOX®, Bao Tuo Shi®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vorinostat in Combination With Bortezomib, Doxorubicin and Dexamethasone (VBDD) in Patients With Refractory or Relapsed Multiple Myeloma (MM)
Status: COMPLETED
Conditions: Multiple Myeloma in Relapse
Interventions: DRUG: Vorinostat|DRUG: Bortezomib|DRUG: Doxorubicin|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Balance PD Solution on the Peritoneal Membrane in Patients on Automated Peritoneal Dialysis
Status: COMPLETED
Conditions: Chronic Renal Failure
Interventions: DRUG: Solution B (balance PD solution)|DRUG: Solution A (conventional PD solution)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Normothermia Maintenance Between Resistive Blanket and Forced Air Warming Systems in Renal Transplant Surgery
Status: RECRUITING
Conditions: Surgery|Temperature Change, Body
Interventions: DEVICE: Forced Air Warming System|DEVICE: Resistive Blanket Warming System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Vestibular Socket Therapy in Immediate Implants With Grafting Materials
Status: UNKNOWN
Conditions: Tooth Extraction|Dental Implant|Extarction Socket
Interventions: OTHER: VST with collagen plug soaked in blood|OTHER: VST with Allograft Demineralized bone matrix Grafton|OTHER: VST with a particulate bone graft composed of two thirds autogenous cortical chips harvested from the surgical site and one third of bovine deprotinzed particles
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Romosozumab (AMG 785) Administered to Healthy Participants and Patients With Stage 4 Renal Impairment or Stage 5 Renal Impairment Requiring Hemodialysis
Status: COMPLETED
Conditions: Osteoporosis
Interventions: DRUG: Romosozumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Klotho and Mineral Bone Density in Systemic Sclerosis
Status: RECRUITING
Conditions: Systemic Sclerosis
Interventions: OTHER: Possible Klotho effects on SSc clinical conditions, namely skeletal, fibrotic and microangiopathic damage|OTHER: Evalution in healthy patients of bone mineral density, Klotho level and key bone-related cytokines
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pilot Study to Assess Efficacy and Safety of Treamid in the Rehabilitation of Patients After COVID-19 Pneumonia
Status: COMPLETED
Conditions: SARS-CoV-2 Infection|Fibrosis Lung
Interventions: DRUG: Treamid|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility of a Novel Exergame-Based Training Concept for Older Adults With Mild Neurocognitive Disorder
Status: COMPLETED
Conditions: Mild Neurocognitive Disorder
Interventions: BEHAVIORAL: Exergame|BEHAVIORAL: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Investigating Changes in Responses to Controlled Effective Doses of Ozone at Different Exercise Intensities
Status: NOT_YET_RECRUITING
Conditions: Ozone|Exercise Intensity
Interventions: OTHER: Ozone|BEHAVIORAL: Heavy Intensity|BEHAVIORAL: Moderate Intensity|OTHER: Filtered Air
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Short-Term Transcutaneous or Epidural Spinal Stimulation for Enabling Motor Function in Humans With SCI
Status: COMPLETED
Conditions: Paraplegia|Tetraplegia|Paralysis|Quadraplegia
Interventions: DEVICE: Percutaneous epidural electrical spinal stimulation|DEVICE: Transcutaneous electrical spinal stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Cord Blood Transplantation for Patients With Cancer
Status: TERMINATED
Conditions: Hematological Disease
Interventions: DRUG: Melphalan|DRUG: Fludarabine|DRUG: Antithymocyte Globulin (ATG)|DRUG: Busulfan|DRUG: Total Body Irradiation (TBI)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Verification of the Efficacy/Safety of the Mixed Drug Injectable Delivery Vehicle for Treating Intractable Hearing Loss
Status: NOT_YET_RECRUITING
Conditions: Hearing Loss, Sensorineural|Hearing Loss, Sudden|Intratympanic Injection
Interventions: DRUG: Dexamethasone|DRUG: Hyaluronic acid|OTHER: Indocyanine green(ICG)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Trial of Cisplatin Plus Radiation Followed by Carbo and Taxol Vs. Sandwich Therapy of Carbo and Taxol Followed Radiation Then Further Carbo and Taxol
Status: COMPLETED
Conditions: Endometrial Clear Cell Adenocarcinoma|Endometrial Serous Adenocarcinoma|Stage IIIA Uterine Corpus Cancer|Stage IIIB Uterine Corpus Cancer|Stage IIIC Uterine Corpus Cancer|Stage IVA Uterine Corpus Cancer
Interventions: DRUG: Cisplatin|DRUG: Carboplatin|DRUG: Paclitaxel|RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Lateralized Thermal Sleepwear on Sleep, Skin Temperature and Skin Moisture in Menopausal Women
Status: TERMINATED
Conditions: Menopause Related Conditions
Interventions: DEVICE: Sleepwear with Lateralized Thermal Characteristics|DEVICE: Sham-Lateralized Sleepwear
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Ischemia and Reperfusion Interval With Neuromonitorization in Tourniquet Application
Status: RECRUITING
Conditions: Quadriceps Muscle Atrophy|Tourniquet|EMG
Interventions: PROCEDURE: Surgical tourniquet pressure selection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy, Safety and Pharmacokinetics of Sugammadex (Org 25969; MK-8616) at 3 Different Time Points After 0.6 mg/kg Esmeron® in Male Participants (P05940; MK-8616-020).
Status: COMPLETED
Conditions: Neuromuscular Blockade
Interventions: DRUG: Placebo|DRUG: Sugammadex|DRUG: Esmeron®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of (Mirapex) Pramipexole for the Early Treatment of Parkinsons Disease (PD)
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: DRUG: pramipexole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Allogeneic HCT With HLA-matched Donors : a Phase II Randomized Study Comparing 2 Nonmyeloablative Conditionings
Status: COMPLETED
Conditions: Hematological Malignancies
Interventions: DRUG: Conditioning regimen: TBI + Fludarabine|DRUG: Conditioning regimen:TLI (8 Gy) + ATG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High Energy Density Pulse Electromagnetic Field for Patients With Adhensive Capsulitis
Status: RECRUITING
Conditions: Adhesive Capsulitis
Interventions: DEVICE: High energy density pulse electromagnetic field|OTHER: physiotherapy|DEVICE: sham High energy density pulse electromagnetic field
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: To Evaluate Pharmacokinetics of Tisotumab Vedotin in Chinese Subjects With Metastatic or Recurrent Solid Malignancies
Status: COMPLETED
Conditions: Solid Malignancies
Interventions: DRUG: Tisotumab Vedotin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Regenerative Surgical Treatment of Peri-implantitis
Status: COMPLETED
Conditions: Failure of Dental Implant Due to Infection|Infection|Inflammation|Peri-implantitis|Bacterial Infections|Bleeding of Subgingival Space|Molecular Sequence Variation|Periodontal Diseases|Mouth Diseases
Interventions: DEVICE: Emdogain®|DEVICE: Surgery alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of a L. Paracasei Strain on Grass Pollen Allergic Rhinitis Subjects
Status: COMPLETED
Conditions: Allergic Rhinitis
Interventions: DIETARY_SUPPLEMENT: probiotic|DIETARY_SUPPLEMENT: probiotic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Mechanisms of Underlying Accelerated Repetitive Transcranial Magnetic Stimulation for Treatment-resistant Depression
Status: RECRUITING
Conditions: Treatment-resistant Depression
Interventions: DEVICE: active iTBS|DEVICE: sham rTMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Fish Oil for the Treatment of Depression in Patients With Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis|Depression
Interventions: DRUG: Fish oil concentrate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: tVNS in Long COVID-19
Status: RECRUITING
Conditions: Long Covid Also Fulfilling Criteria for Chronic Fatigue Syndrome
Interventions: DEVICE: Transcutaneous vagus nerve stimulator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Telehealth Delivered Physical Rehabilitation for an Ankle Sprain
Status: RECRUITING
Conditions: Ankle Sprains|Telerehabilitation|Analgesic, Opioid|Analgesics, Non-narcotic|Anti-Inflammatory Agents, Non-Steroidal|Implementation Science|Acute Pain|Quality of Life
Interventions: OTHER: Telehealth Protocol|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: HIFU Hyperthermia With Liposomal Doxorubicin (DOXIL) for Relapsed or Refractory Pediatric and Young Adult Solid Tumors
Status: WITHDRAWN
Conditions: Rhabdomyosarcoma|Neuroblastoma|Sarcoma|Sarcoma, Ewing|Osteosarcoma|Desmoid
Interventions: DRUG: Doxorubicin HCl liposomal injection|DEVICE: Philips Sonalleve MR-HIFU Hyperthermia
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Inflammatory Effects of a Lung Recruitment Manoeuvre
Status: UNKNOWN
Conditions: Respiratory Insufficiency|Respiratory Distress Syndrome, Adult
Interventions: PROCEDURE: 40/30 recruitment manoeuvre|DEVICE: continuous positive airway pressure (CPAP)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Study of Orlistat and SLx-4090 for the Treatment of Type 1 Hyperlipoproteinemia
Status: TERMINATED
Conditions: Type 1 Hyperlipoproteinemia
Interventions: DRUG: SLx-4090 placebo|DRUG: Orlistat Placebo|DRUG: Orlistat|DRUG: Slx-4090
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Breast Cancer Rehabilitation Program in Improving Quality of Life in Breast Cancer Survivors
Status: COMPLETED
Conditions: Stage I Breast Cancer|Stage II Breast Cancer|Stage IIIA Breast Cancer|Stage IIIB Breast Cancer|Stage IIIC Breast Cancer|Stage IV Breast Cancer
Interventions: OTHER: questionnaire administration|BEHAVIORAL: exercise intervention|PROCEDURE: quality-of-life assessment|OTHER: survey administration|PROCEDURE: management of therapy complications|PROCEDURE: psychosocial assessment and care
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bortezomib, Isatuximab, Cyclophosphamide and Dexamethasone Induction in Transplant-Eligible Multiple Myeloma Patients
Status: RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: Bortezomib|DRUG: Isatuximab|DRUG: Cyclophosphamide|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Auriculotherapy for Prevention of Postoperative Urinary Retention
Status: COMPLETED
Conditions: Analgesia, Epidural
Interventions: PROCEDURE: Control|PROCEDURE: Treated|PROCEDURE: Intra-venous anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Intrafractional Vaginal Dilation in Anal Cancer Patients Undergoing Pelvic Radiotherapy
Status: RECRUITING
Conditions: Anal Cancer
Interventions: DEVICE: special tampon with a diameter of 28mm|DEVICE: standard tampon with a diameter of 12-13mm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study of HX008 Plus Transcatheter Arterial Chemoembolization (TACE) in the First-Line Treatment of Subjects With Stage IV (M1c) Melanoma That is Metastatic to the Liver
Status: NOT_YET_RECRUITING
Conditions: Melanoma Neuroendocrine Tumors Neuroectodermal Tumors Neoplasms Germ Cell and Embryonal Neoplasms by Histologic Type Neoplasms Neoplasms
Interventions: DRUG: HX008 + TACE|DRUG: Temozolomide + TACE|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of GW433908 and Nelfinavir in HIV Patients Who Have Not Had Antiretroviral Therapy
Status: UNKNOWN
Conditions: HIV Infections
Interventions: DRUG: Abacavir sulfate|DRUG: Nelfinavir mesylate|DRUG: Lamivudine|DRUG: GW433908
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: Alfimeprase for Thrombolysis in Acute Peripheral Arterial Occlusion
Status: COMPLETED
Conditions: Arterial Occlusive Diseases|Peripheral Vascular Diseases|Thrombosis
Interventions: DRUG: Alfimeprase
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Myocardial Protection and Clinical Outcome in Patients Undergoing Tetralogy of Fallot Repair : A Randomized Study of Two Different Cardioplegia Technique
Status: COMPLETED
Conditions: Myocardial Protection in TOF Repair
Interventions: OTHER: blood cardioplegia|OTHER: del nido cardioplegia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of a Cardiovascular Active Prevention in Chronic Myeloid Leukemia on the Cardiovascular Morbi-mortality
Status: UNKNOWN
Conditions: Chronic Myeloid Leukemia (CML)
Interventions: COMBINATION_PRODUCT: Optimal medical treatment|COMBINATION_PRODUCT: usual clinical practice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: To Determine Blood Concentrations of Ibuprofen and Caffeine in a Tablet Against Ibuprofen Alone From Another Tablet
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Ibuprofen|DRUG: Caffeine|DRUG: Ibuprofen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study: Randomized, Placebo-controlled Comparator Trial of IV vs Oral Iron Treatment of RLS With IDA. (IVOR-IDA)
Status: COMPLETED
Conditions: Restless Legs Syndrome|Iron Deficiency Anemia
Interventions: DRUG: Ferumoxytol intravenous|DRUG: Ferrous sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: YoBEKA Program (Yoga, Movement, Relaxation, Concentration and Mindfulness) in Elementary Schools
Status: COMPLETED
Conditions: Stress, Psychological
Interventions: BEHAVIORAL: YoBEKA
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Positron Emission Tomography (PET) Imaging of Brain Amyloid Compared to Post-Mortem Levels
Status: COMPLETED
Conditions: Brain Fibrillarab Levels
Interventions: DRUG: [18F] Flutemetamol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effectiveness of Nigella Sativa (Kalonji) Seed in Dyslipidemia
Status: COMPLETED
Conditions: Hypercholesterolemia|Hypertension|Diabetes Mellitus|Metabolic Syndrome X
Interventions: DRUG: Nigella sativa seed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Safety, Pharmacokinetics and Pharmacodynamics of TA-7284 in Type 2 Diabetic Patients
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: TA-7284|DRUG: Placebo of TA-7284
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: New Strategy for the Detection and Treatment of Helicobacter Pylori Infections in Primary Care Guided by a Non-invasive PCR in Stool
Status: RECRUITING
Conditions: Helicobacter Pylori Infection
Interventions: DIAGNOSTIC_TEST: PCR test in the stool
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Influence of Probiotic and Symbiotic in Body Weight, Blood Sugar and Lipemia of Obese Women
Status: COMPLETED
Conditions: Obesity
Interventions: DIETARY_SUPPLEMENT: Probiotic|DIETARY_SUPPLEMENT: Symbiotic|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Local Anaesthesia vs Regional Block for Arteriovenous Fistulae
Status: UNKNOWN
Conditions: End Stage Renal Disease
Interventions: PROCEDURE: Local Anaesthetic|PROCEDURE: Regional anaesthetic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use Of Intracameral Moxifloxacin For Prophylaxis Of Open Globe Endophthalmitis
Status: UNKNOWN
Conditions: Endophthalmitis|Trauma, Corneal
Interventions: DRUG: Intraocular Instillation Solution|DRUG: Moxifloxacin Ophthalmic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluation and Optimization of Hearing Devices in 3-D Complex Audio Environments Study 3 (HEAR3D_CE3)
Status: COMPLETED
Conditions: Ability, Spatial
Interventions: PROCEDURE: Effect of several processing on the auditory distance perception
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Screening for NAFLD-related Advanced Fibrosis in High Risk Population in Diabetology.
Status: UNKNOWN
Conditions: Non-Alcoholic Fatty Liver Disease
Interventions: DIAGNOSTIC_TEST: Non-invasive blood-based and imaging-based tests for the screening of NAFLD-related advanced fibrosis.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Pursuing the Triple Aim in Hotspotters: Identification and Integrated Care
Status: ENROLLING_BY_INVITATION
Conditions: Complex Patient|Multimorbidity|Psychosocial Problem|Chronic Disease
Interventions: OTHER: Proactive, integrated and personalised care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Pharmaco-imaging Approach to Predicting Social Functioning and Clinical Responses to Oxytocin Administration in Schizophrenia
Status: TERMINATED
Conditions: Schizophrenia
Interventions: DRUG: Oxytocin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Strengthening Exercise Program Compare With Foot Orthoses in Patients With Plantar Heel Pain
Status: RECRUITING
Conditions: Plantar Fascitis|Fasciitis, Plantar, Chronic
Interventions: OTHER: Strengthening exercise|OTHER: Insole (CFO) group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Novel mHealth Application Guided by an Optimization Algorithm for T1D Sensor-Augmented Insulin Injection Users
Status: COMPLETED
Conditions: Diabetes Mellitus|Diabetes Mellitus, Type 1
Interventions: DEVICE: Mobile App|DEVICE: Mobile App + Basal-Bolus Optimization Algorithm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Ultrasound Guided L1,L2 Paravertebral Block in Decrease the Requirements for Hypotensive Drugs During General Anesthesia in Patients Undergoing Hip Surgeries.
Status: COMPLETED
Conditions: Ultrasound Guided L1,L2 Paravertebral Block
Interventions: PROCEDURE: Ultrasound guided PVB with General Aneasthesia|DEVICE: Ultrasound|DRUG: Paravertebral block|DRUG: General Aneasthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Digital Detection of Dementia (D Cubed) Studies: D2
Status: ACTIVE_NOT_RECRUITING
Conditions: Alzheimer Disease and Related Dementias (ADRD)
Interventions: OTHER: Passive Digital Marker for screening for ADRD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Pulmonary Artery Sensor System Pressure Monitoring to Improve Heart Failure (HF) Outcomes
Status: RECRUITING
Conditions: Heart Failure
Interventions: DEVICE: CardioMEMSTM HF sensor - pulmonary artery pressure measurement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Total Knee Arthroplasty Biomechanics
Status: COMPLETED
Conditions: Total Knee Arthroplasty (TKA)
Interventions: BEHAVIORAL: Home Strengthening Exercises|OTHER: Standard Physical Therapy|OTHER: Preoperative Assessments
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Topiroxostat on Urinary Albumin Excretion Early Stage Diabetic Nephropathy and Hyperuricemia With or Without Gout
Status: COMPLETED
Conditions: Diabetic Nephropathy
Interventions: DRUG: Topiroxostat BID, (Oral daily dosing for 28 weeks)|DRUG: Placebo BID, (Oral daily dosing for 28 weeks)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Prospective CGM Quality Improvement (QI) Project in Pregnancy
Status: COMPLETED
Conditions: Diabetes Mellitus, Type I
Interventions: DEVICE: Dexcom G4 or G5 Platinum CGM system|DEVICE: Dexcom G4 or G5 Platinum CGM system with Share
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transcranial Direct Current Stimulation in Stroke Rehabilitation
Status: UNKNOWN
Conditions: Stroke
Interventions: DEVICE: Application of Transcranial direct current stimulation (TDCS)|DEVICE: Transcranial Direct current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Brief Mindfulness Intervention for Stress, Anxiety and Burnout in Mental Health Professionals
Status: COMPLETED
Conditions: Mental Health Wellness 1
Interventions: BEHAVIORAL: Sitting Mindfulness Exercises.|BEHAVIORAL: Body Mindfulness Exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study for Patients With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Human Insulin Inhalation Powder|DRUG: Neutral protamine hagedorn insulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Analgesic Efficacy of Ibuprofen Alone and Ibuprofen Plus Hyoscine-n- Butyl Bromide in Reducing Pain of Outpatient Hysteroscopy
Status: NOT_YET_RECRUITING
Conditions: Pain
Interventions: DRUG: Ibuprofen 400 mg|DRUG: Hyoscine N-Butil Bromide|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Taichi for Overweight/Obese Adolescent and Young Women With Polycystic Ovary Syndrome (PCOS)
Status: UNKNOWN
Conditions: Polycystic Ovary Syndrome
Interventions: BEHAVIORAL: Taichi|BEHAVIORAL: Self-monitored exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Single Dose of Pembrolizumab in HIV-Infected People
Status: RECRUITING
Conditions: Human Immunodeficiency Virus
Interventions: OTHER: Placebo|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Behavioral Depression Treatment for African American HIV-infected Substance Users
Status: COMPLETED
Conditions: Depression|Substance Use
Interventions: BEHAVIORAL: ACT HEALTHY|BEHAVIORAL: Nondirective Therapy (NDT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: To Assess the Safety and Tolerance of Infant Formula With Locust Bean Gum in Infants With Regurgitation
Status: COMPLETED
Conditions: Regurgitation, Gastric|Diarrhea
Interventions: OTHER: milk based anti-regurgitation infant formula|OTHER: Milk based infant formula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: [68Ga]Ga-FAPI PET/CT in Gastric and Gastroesophageal Junctional Cancer
Status: RECRUITING
Conditions: Gastric Cancer|Gastro Esophageal Junctional Cancer|Cancer
Interventions: DRUG: 68Ga-FAPi-46
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Single-center Study on Laparoscopic Distal Subtotal Gastrectomy for Advanced Gastric Cancer
Status: UNKNOWN
Conditions: Stomach Neoplasms
Interventions: PROCEDURE: Laparoscopic gastrectomy|PROCEDURE: Open gastrectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Montelukast From Asmakast 5mg Chewable Tab.(Sandoz, Egypt) & Singulair 5mg Chewable Tab.(Merck)
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Asmakast|DRUG: Singulair
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Safety and Immunogenicity of the Bris10 M2SR and Sing2016 M2SR H3N2 Monovalent Influenza Vaccines
Status: COMPLETED
Conditions: Influenza A
Interventions: BIOLOGICAL: LD Sing2016 M2SR H3N2 influenza vaccine|BIOLOGICAL: MD Sing2016 M2SR H3N2 influenza vaccine|BIOLOGICAL: HD Sing2016 M2SR H3N2 influenza vaccine|BIOLOGICAL: LD Bris10 M2SR H3N2 influenza vaccine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study To Measure The Level Of Drug In Nasal Tissue And Blood After Taking A Single 2g Dose Or 500mg Tablets For Up To
Status: COMPLETED
Conditions: Sinusitis
Interventions: DRUG: Zithromax&#153; (azithromycin) 500mg tablets|PROCEDURE: Endoscopic Sinus Surgery|PROCEDURE: Blood sampling for hematology|PROCEDURE: Blood sampling for plasma chemistry profile|PROCEDURE: Serum pregnancy test (for women of child-bearing potential)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Efficacy of Oral vs IV Antibiotics in the Treatment of Orofacial Osteomyelitis
Status: NOT_YET_RECRUITING
Conditions: Osteomyelitis of Jaw
Interventions: DRUG: Amoxicillin-clavulanate 875mg/125mg q12hrs|DRUG: oral clindamycin 300mg q6hrs|DRUG: Levofloxacin 750mg QID
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Brief Postoperative Hypnosis Intervention as Multimodal Analgesia After Major Abdominal Surgery
Status: COMPLETED
Conditions: Hypnosis|ERAS|Postoperative Pain
Interventions: BEHAVIORAL: Hypnosis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cartoons and Musical-moving Toys in Invasive Procedure Applications Reduce Pain and Fear Levels of Children
Status: COMPLETED
Conditions: Pediatric Disorder
Interventions: BEHAVIORAL: Cartoons|BEHAVIORAL: musical-moving toys
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Accuracy of Ultrasound in Detecting Rotator Cuff Tears in Proximal Humerus Fracture Patients
Status: TERMINATED
Conditions: Rotator Cuff Tear|Proximal Humeral Fracture
Interventions: DIAGNOSTIC_TEST: Ultrasound examination of the rotator cuff tendons
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Efficacy of Carbone Dioxide (CO2) Laser System in Treatment of Female Stress Urinary Incontinence.
Status: UNKNOWN
Conditions: Female Stress Urinary Incontinence
Interventions: DEVICE: Alma Lasers Pixel carbon dioxide laser system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study in Non-responder Hepatitis C Genotype 1 Patients With EMZ702, Pegylated Interferon and Ribavirin
Status: COMPLETED
Conditions: Chronic Hepatitis C|Hepatitis, Viral, Human
Interventions: DRUG: EMZ702
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Lasofoxifene Combined With Abemaciclib in Advanced or Metastatic ER+/HER2- Breast Cancer With an ESR1 Mutation
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Breast Cancer
Interventions: DRUG: Lasofoxifene and abemaciclib (VERZENIO (R)).
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reducing Fall Risk Post Hip Fracture in Mild Cognitive Impairment
Status: ACTIVE_NOT_RECRUITING
Conditions: Hip Fractures|Mild Cognitive Impairment
Interventions: BEHAVIORAL: Otago Exercise Program|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Physical Activity Intervention for Hematopoietic Cell Transplant Recipients and Caregivers
Status: ACTIVE_NOT_RECRUITING
Conditions: Hematopoietic Cell Transplant
Interventions: BEHAVIORAL: Integrated health counseling and step prescription
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety of 16.5 mg (3.3%) CGC-11047 Once Every 2 Weeks vs. Once Every 4 Weeks in Patients With CNV Due to AMD
Status: COMPLETED
Conditions: Age Related Macular Degeneration
Interventions: DRUG: CGC-11047
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Safety, Tolerability and Pharmacokinetics of BSG005.
Status: RECRUITING
Conditions: Invasive Fungal Infections
Interventions: DRUG: BSG005 or placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigate the Effect of Food on the Pharmacokinetic Characteristics of CKD-395 in Healthy Male Volunteers
Status: COMPLETED
Conditions: Diabetes Mellitus, Type II
Interventions: DRUG: CKD-395 0.5(Lobeglitazone)/1000(Metformin)mg 1T|DRUG: CKD-395 0.5(Lobeglitazone)/1000(Metformin)mg 1T
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sulfur Colloid SPECT/CT in Measuring Liver Function in Patients With Primary or Metastatic Liver Cancer Undergoing Radiation Therapy or Surgery
Status: RECRUITING
Conditions: Hepatocellular Carcinoma|Intrahepatic Cholangiocarcinoma|Stage IV Liver Cancer|Stage IVA Liver Cancer|Stage IVB Liver Cancer|Vascular Thrombosis
Interventions: PROCEDURE: Computed Tomography|PROCEDURE: Single Photon Emission Computed Tomography|DRUG: Technetium Tc-99m Sulfur Colloid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Sphenopalatine Ganglion Block Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Sphenopalatine Ganglion Nerve Block
Interventions: DRUG: Bupivacaine|DEVICE: angiocatheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intermittent Exogenous Ketosis (IEK) at High Altitude
Status: ACTIVE_NOT_RECRUITING
Conditions: Ketosis|Hypoxia
Interventions: DIETARY_SUPPLEMENT: Ketone ester|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Treatment With the Ablative Fractional Carbodioxide Laser in Vulvar Lichen Sclerosis
Status: UNKNOWN
Conditions: Lichen Sclerosus Et Atrophicus of the Vulva
Interventions: DEVICE: Active microablative fractional CO2 laser designed as SmartXide Touch C60, CO2 laser system for MonaLisa Touch, DEKA, Florence|DEVICE: Sham microablative fractional CO2 laser designed as SmartXide Touch C60, CO2 laser system for MonaLisa Touch, DEKA, Florence
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness and Safety of Enbrel® (Etanercept) in Rheumatoid Arthritis Subjects Who Have Failed Remicade® (Infliximab)
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Etanercept
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Remote Ischemic Preconditioning for Intracranial Aneurysm Treatment
Status: UNKNOWN
Conditions: Cerebral Aneurysm
Interventions: PROCEDURE: Remote ischemic preconditioning|PROCEDURE: Sham preconditioning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Is There a Genetic Predisposition for Acute Stress-induced (Takotsubo) Cardiomyopathy
Status: RECRUITING
Conditions: Takotsubo Cardiomyopathy
Interventions: GENETIC: Blood collection for genetic analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Phase II Safety and Efficacy Study of 18FDOPA PET-CT in Children With Hyperinsulinemic Hypoglycemia
Status: COMPLETED
Conditions: Congenital Hyperinsulinism (CHI)|Persistent Hyperinsulinemic Hypoglycemia of Infancy (PHHI)
Interventions: DRUG: 18 F-DOPA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Lenalidomide and Radiation Therapy in High Grade Gliomas or Diffuse Intrinsic Pontine Gliomas
Status: COMPLETED
Conditions: Diffuse Intrinsic Pontine Glioma|Anaplastic Astrocytoma|High Grade Glioma
Interventions: DRUG: Lenalidomide|RADIATION: XRT, 54-59.4 Gy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: THRIVE in Children at Different Flow Rates
Status: COMPLETED
Conditions: Apnea|Ventilation Therapy; Complications
Interventions: OTHER: THRIVE 4L/kg/min|OTHER: THRIVE 2L/kg/min
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Probiotics to Actively Counter Ventilator Associated Pneumonia (PROACT)
Status: RECRUITING
Conditions: Ventilator Associated Pneumonia
Interventions: DIETARY_SUPPLEMENT: LactoLevure|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Head-Neck Stretching Exercises After Thyroidectomy on Postoperative Pain Level and Wound Healing
Status: COMPLETED
Conditions: Postoperative Pain|Postoperative Wound Complication
Interventions: OTHER: head-neck stretching exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Assess the Long- Term Safety of TC-5214 as an Adjunct Therapy in Patients With Major Depressive Disorder
Status: COMPLETED
Conditions: Major Depressive Disorder|MDD|Depression
Interventions: DRUG: TC-5214|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Template Assisted Monochromatic Structural Colored Versus Universal Multi-Shade Direct Composite Veneers
Status: COMPLETED
Conditions: Tooth Discoloration
Interventions: OTHER: Omnichroma|OTHER: Ceram. X Spectra
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigation of Pharmacodynamic Effects of Dabigatran and Ticagrelor and Assessment of Ticagrelor Interaction Potential With Dabigatran
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: dabigatran etexilate|DRUG: Ticagrelor|DRUG: Ticagrelor|DRUG: dabigatran etexilate|DRUG: dabigatran etexilate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT