pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Cycling of Topical Steroids for Treatment of EoE (Eosinopilic Esophagitis)
Status: COMPLETED
Conditions: Eosinophilic Esophagitis
Interventions: DRUG: Fluticasone Propionate|DRUG: Budesonide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Modulation of Visual-Spatial Learning in Patients With Mild Cognitive Impairment (MCI) by tDCS
Status: COMPLETED
Conditions: Mild Cognitive Impairment (MCI)
Interventions: DEVICE: tDCS|BEHAVIORAL: training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Investigation on the Effects of ClearSkin Non-ablative ER:Glass 1540nm Laser Module in the Treatment of Acne Scars.
Status: NOT_YET_RECRUITING
Conditions: Acne Scars - Mixed Atrophic and Hypertrophic
Interventions: DEVICE: Alma Harmony
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: H (Trastuzumab or Biosimilar) Combined With CDK4/6 Inhibitor + AI±OFS in the Treatment of HR+HER2+ Advanced Breast Cancer Efficacy and Safety: a Chinese Multi-center Real World Study
Status: UNKNOWN
Conditions: Advanced HR+ HER2 Negative Breast Carcinoma
Interventions: DRUG: Enituzumab injection+Abesili tablets+Anastrozole tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mutual Interactions Between Absence Epilepsy Seizures and the Integration of Sensory Stimuli
Status: TERMINATED
Conditions: Childhood or Juvenile Absence Epilepsy
Interventions: PROCEDURE: Timed repetitive sensory stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SL-401 in Combination With Azacitidine or Azacitidine/Venetoclax in Acute Myeloid Leukemia (AML), High-Risk Myelodysplastic Syndrome (MDS) or Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN)
Status: RECRUITING
Conditions: Acute Myeloid Leukemia|Myelodysplastic Syndrome|Blastic Plasmacytoid Dendritic Cell Neoplasm
Interventions: DRUG: Azacitidine|DRUG: SL-401|DRUG: Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mini-treatment Experiments to Clarify How to Assist People to Habit Formation
Status: COMPLETED
Conditions: Sleep Disorder|Circadian Dysregulation|Habit, Good Sleep
Interventions: BEHAVIORAL: RISE-UP Routine|BEHAVIORAL: Awareness Training|BEHAVIORAL: Vigilant Monitoring|BEHAVIORAL: Implementation Intentions|BEHAVIORAL: Values-based Approach|BEHAVIORAL: Brief Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Effects of Peer Co-led Educational Group Intervention for Adults With Attention-Deficit Hyperactivity Disorder
Status: COMPLETED
Conditions: Attention Deficit Disorder With Hyperactivity
Interventions: BEHAVIORAL: Group-based education|BEHAVIORAL: Waiting list|OTHER: Standard treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effects of Orofacial Myofunctional Therapy on Mental Functioning and Overall Self-Sufficiency in Stroke Patients
Status: UNKNOWN
Conditions: Stroke
Interventions: OTHER: Routine physical therapy treatment|OTHER: Routine physical therapy along with orofacial therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Safety and the Efficacy of Carfilzomib Combined With Cyclophosphamide and Dexamethasone (CCyd) or Lenalidomide and Dex (CRd) Followed by ASCT or 12 Cycles of Carf Combined With Dex and Len for Patients Eligible for ASCT With Newly Diagnosed Multiple Myeloma.
Status: ACTIVE_NOT_RECRUITING
Conditions: MULTIPLE MYELOMA (MM)
Interventions: DRUG: Carfilzomib|DRUG: Cyclophosphamide|DRUG: Lenalidomide|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigation of the Naída CI M90 Sound Processor in Various Acoustic Scenarios
Status: COMPLETED
Conditions: Cochlear Hearing Loss
Interventions: DEVICE: Naída CI M90 Sound Processor (hearing aid and cochlea implant sound processor)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Usefulness and Safeness Of Intra-Gastric Balloon Before Bariatric Surgery In Morbid Obesity
Status: COMPLETED
Conditions: Morbid Obesity
Interventions: DEVICE: Intragastric Balloon (IGB), group A|OTHER: diet, control group B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Impact of a Multidimensional ICT Intervention on the Quality of Life of Breast Cancer Survivors
Status: COMPLETED
Conditions: Breast Cancer|Breast Neoplasms|Quality of Life|Survivorship
Interventions: OTHER: Xemio mobile application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Cognitive Protection - Dexmedetomidine and Cognitive Reserve
Status: TERMINATED
Conditions: Postoperative Delirium|PD|Postoperative Cognitive Dysfunction|POCD
Interventions: DRUG: Precedex (Dexmedetomidine)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Muscle Strength, Functional Capacity, Respiratory Function and Quality Of Life In Cystic Fibrosis Patients
Status: COMPLETED
Conditions: Cystic Fibrosis|Muscle Strength|Pulmonary Function|Functional Capacity|Exercise Tolerance|Muscular Endurance
Interventions: OTHER: cystic fibrosis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: MR Colonography With Fecal Tagging. Barium vs. BariumFerumoxsil
Status: COMPLETED
Conditions: Colorectal Cancer|Polyps
Interventions: PROCEDURE: MR colonography with fecal tagging
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Yellow Fever Vaccine Immunity in HIV Infected Patients : Development of New Assays for Virological and Immunological Monitoring in HIV Infected Patient.
Status: COMPLETED
Conditions: HIV Infection|Yellow Fever
Interventions: BIOLOGICAL: Yellow fever vaccination (STAMARIL)|BIOLOGICAL: Yellow fever vaccination (STAMARIL)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of Gamma Interfereon in Metastatic Colorectal Carcinoma
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: 5-Fluorouracil|DRUG: Leucovorin (LV)|DRUG: Gamma-Interferon-1b (IFN-γ)|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Studies of Ocular Complications of AIDS (SOCA)--Ganciclovir-Cidofovir CMV Retinitis Trial (GCCRT)
Status: COMPLETED
Conditions: Cytomegalovirus Retinitis|HIV Infections
Interventions: DEVICE: Ganciclovir implant and oral ganciclovir|DRUG: Cidofovir intravenous
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Trial Comparing Sirolimus and Tacrolimus Versus Cyclosporine and Methotrexate as Graft-versus-host Disease (GVHD) Prophylaxis After Allogeneic Stem Cell Transplantation
Status: COMPLETED
Conditions: Graft-versus-host Disease|Survival
Interventions: DRUG: Sirolimus/tacrolimus|DRUG: cyclosporine/methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Myocardial Protection With Phosphocreatine in High-RIsk Cardiac SurgEry Patients
Status: COMPLETED
Conditions: Cardiac Surgical Procedures|Heart Valve Prosthesis Implantation
Interventions: DRUG: Phosphocreatine sodium tetrahydrate after anaesthesia induction|DRUG: 5% Glucose after anaesthesia induction|DRUG: Phosphocreatine sodium tetrahydrate added to cardioplegia|DRUG: 5% Glucose|DRUG: Phosphocreatine sodium tetrahydrate after heart recovery|DRUG: 5% Glucose after heart recovery|DRUG: Phosphocreatine sodium tetrahydrate after ICU admission|DRUG: 5% Glucose after ICU admission
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pomalidomide and Nivolumab in People With Virus-Associated Malignancies With or Without HIV
Status: RECRUITING
Conditions: Viral Associated Malignancies|Kaposi Sarcoma|EBV/KSHV-associated Lymphomas
Interventions: DRUG: Pomalidomide|DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Ceftaroline in Elderly Subjects With Community-Acquired Bacterial Pneumonia
Status: WITHDRAWN
Conditions: Community-Acquired Bacterial Pneumonia (CABP)
Interventions: DRUG: Ceftaroline fosamil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Dose-Defining Study of CXL-1020 in Patients With Systolic Heart Failure
Status: COMPLETED
Conditions: Heart Failure
Interventions: DRUG: Placebo|DRUG: Strata 1 CXL-1020|DRUG: Strata 2 CXL-1020|DRUG: Strata 3 CXL-1020
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PI Vs. NNRTI Based Therapy for HIV Advanced Disease
Status: UNKNOWN
Conditions: Acquired Immunodeficiency Syndrome
Interventions: DRUG: zidovudine+lamivudine+lopinavir/ritonavir|DRUG: zidovudine + lamivudine + efavirenz
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I, Multicenter, Randomized Trial to Evaluate the Safety and Immunogenicity of Vaccinia-Derived MN HIV-1 Recombinant Envelope Glycoprotein (rgp160) of Human Immunodeficiency Virus at Two Different Vaccination Schedules
Status: COMPLETED
Conditions: HIV Infections|HIV Seronegativity
Interventions: BIOLOGICAL: gp160 Vaccine (Immuno-AG)
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: PREVENTION
Clinical trial: Reinforcement of Surgical Staple Lines Using Peri-Strips Dry (PSD) With Veritas Collagen Matrix
Status: COMPLETED
Conditions: Obesity
Interventions: DEVICE: PSD Veritas Collagen Matrix|PROCEDURE: Roux-en-Y gastric by-pass surgery with no buttress
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Quantitative Assessment of Sucking for Early Diagnosis of Brain Injury in Infants at High Risk
Status: TERMINATED
Conditions: Hypoxic-Ischemic Encephalopathy|Hypoglycemia|Neonatal Abstinence Syndrome
Interventions: DEVICE: nfant feeding solution
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Gentamicin in Cardiac Surgery
Status: COMPLETED
Conditions: Cardiac Infection
Interventions: DRUG: Flucloxacillin and gentamicin|DRUG: Flucloxacillin and ceftriaxone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Nevirapine Drug Levels in HIV Positive Patients Also Receiving Rifampicin for Tuberculosis
Status: COMPLETED
Conditions: HIV Infections|Tuberculosis
Interventions: DRUG: Nevirapine without dose escalation|DRUG: Nevirapine initiation with dose escalation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Behavioral Activation/Armodafinil to Treat Fatigue in HIV/AIDS
Status: COMPLETED
Conditions: Hiv|Fatigue|Goals
Interventions: BEHAVIORAL: Behavioral Activation Therapy|BEHAVIORAL: Supportive Counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: GP-induced Chemotherapy Combined With IMRT and TPF-induced Chemotherapy Combined With IMRT in the Treatment of Distant Metastatic Nasopharyngeal Carcinoma
Status: UNKNOWN
Conditions: Advanced Nasopharyngeal Carcinoma
Interventions: DRUG: GP+IMRT|DRUG: TPF+IMRT
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: WEDGES: Coronary Lesion Preparation With Enhanced Dilatation for Good Expansion of Stent: Assessment of a New Scoring Balloon by Quantitative Stent Enhanced Visualization
Status: UNKNOWN
Conditions: Coronary Artery Disease
Interventions: DEVICE: Wedge Scoring Balloon|DEVICE: Conventional Balloon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ultrasound Guided Central Vein Catheterization and Complications
Status: COMPLETED
Conditions: Brain Tumor
Interventions: PROCEDURE: Catheterization of subclavian vein|PROCEDURE: Catheterization of internal jugular vein
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Adipose-derived MSC to Treat Rejection in Kidney Transplant Recipients
Status: RECRUITING
Conditions: Kidney Transplant
Interventions: BIOLOGICAL: Low dose adipose tissue derived mesenchymal stromal cells (A-MSC)|BIOLOGICAL: High dose adipose tissue derived mesenchymal stromal cells (A-MSC)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Examine the Effect of Particle Size on Bioequivalence and Bioavailability
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)|Rheumatoid Arthritis|Atherosclerosis
Interventions: DRUG: GW856553
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PRagmatic EVAluation of a Quality Improvement Program for People Living With Modifiable High-risk COPD.
Status: RECRUITING
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: OTHER: CONQUEST Quality Improvement Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Continuous Supraglottic pH Monitoring in Prolonged Intubated Intensive Care Patients and High Risk Aspiration Intraoperative Patients
Status: TERMINATED
Conditions: Aspiration, Respiratory
Interventions: OTHER: pH monitoring|OTHER: accelerometer monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Safety, Tolerability, and Efficacy of JBT-101 in Subjects With Dermatomyositis
Status: TERMINATED
Conditions: Dermatomyositis
Interventions: DRUG: JBT-101|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of Personalized Genomic Vaccine to Treat Malignancies
Status: COMPLETED
Conditions: Solid Tumors
Interventions: BIOLOGICAL: Peptides|DRUG: Poly-ICLC|DRUG: Lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Campral (Acamprosate) for Alcohol Dependence in a Family Medicine Clinic
Status: COMPLETED
Conditions: Alcohol Dependence
Interventions: DRUG: Acamprosate (Campral)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acupuncture for Postoperative Nausea and Vomiting in Patients Undergoing Colorectal Surgery
Status: COMPLETED
Conditions: Postoperative Nausea and Vomiting|Colorectal Neoplasms
Interventions: PROCEDURE: High-dose acupuncture with intravenous infusion of ramosetron|DEVICE: P6 stimulation with intravenous infusion of ramosetron|DRUG: Intravenous infusion of ramosetron
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Electronic Patient-reported Outcome Monitoring in Aplastic Anemia and Paroxysmal Nocturnal Hemoglobinuria
Status: COMPLETED
Conditions: Aplastic Anemia|Paroxysmal Nocturnal Hemoglobinuria
Interventions: OTHER: symptom questionnaire|OTHER: recording of vital signs|OTHER: European Organisation for Research and Treatment of Cancer (EORTC) quality of life questionnaire (QLQ)-C30 questionnaire|OTHER: interview
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Computer-based Drug and Alcohol Training Assessment in Kenya
Status: COMPLETED
Conditions: Alcohol-Related Disorders|Social Stigma|Substance-Related Disorders
Interventions: BEHAVIORAL: Brief Intervention in Public Clinic|BEHAVIORAL: Screening Results in Public Clinic|BEHAVIORAL: Brief Intervention in Private Clinic|BEHAVIORAL: Screening Results in Private Clinic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing Platelet-Rich Fibrin + Hyaluronic Acid vs. Hyaluronic Acid for TMJ Internal Derangement
Status: NOT_YET_RECRUITING
Conditions: Tmj Internal Derangment
Interventions: COMBINATION_PRODUCT: (Arthrocentesis following i-PRF +HA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Evaluation of Redo Ablation Procedures of Atrial Fibrillation With FIRM Guided Procedures
Status: COMPLETED
Conditions: Persistent Atrial Fibrillation|Paroxysmal Atrial Fibrillation
Interventions: PROCEDURE: Standard PVI|PROCEDURE: FIRM-Guided Procedure and PVI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Multicenter, 4-week Crossover (Total Duration 12 Weeks) to Determine the Impact of QVA149 on Nocturnal Oxygen Levels in Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: QVA149|DRUG: QVA149 Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Two and Six- Minute Walk Tests in Evaluating Oxygen Desaturation in Patients With Severe COPD
Status: COMPLETED
Conditions: Chronic Obstructive Lung Disease
Interventions: OTHER: walk tests
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Magnesium on Dose of Rocuronium for Deep Neuromuscular Blockade
Status: COMPLETED
Conditions: Magnesium Sulfate Causing Adverse Effects in Therapeutic Use|Neuromuscular Blockade
Interventions: DRUG: Magnesium Sulfate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Trial of S-1 Maintenance Therapy in Metastatic Esophagogastric Cancer
Status: COMPLETED
Conditions: Unresectable, Locally Advanced or Metastatic, Adenocarcinoma of the Stomach, or of the Gastro Esophageal Junction|Gastric Neoplasm|Gastroesophageal Junction Adenocarcinoma|Esophageal Adenocarcinoma|Gastric Adenocarcinoma|Esophageal Neoplasms
Interventions: DRUG: S-1 de-escalation|DRUG: Chemotherapy by Investigator's choice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I/II Study of KB103, a Topical HSV1-COL7, on DEB Patients
Status: COMPLETED
Conditions: Dystrophic Epidermolysis Bullosa
Interventions: BIOLOGICAL: Topical beremagene geperpavec|BIOLOGICAL: Placebo gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Prevalence and Predictors of Gastrointestinal Symptoms in Children With Attention Deficit / Hyperactivity Disorder
Status: UNKNOWN
Conditions: Attention Deficit Disorder With Hyperactivity|Gastrointestinal Diseases
Interventions: OTHER: Known diagnosis of attention deficit / hyperactivity disorder
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: UC-GENOME: Urothelial Cancer-GENOmic Analysis to iMprove Patient Outcomes and rEsearch
Status: COMPLETED
Conditions: Urothelial Carcinoma|Bladder Cancer|Urethral Cancer|Cancer of the Ureter
Interventions: OTHER: Biospecimen Collection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Discovering Novel Cancer Treatment Options Using a Comprehensive NGS-based Liquid Molecular Testing Panel in the Community Setting ("DINOSAur II")
Status: RECRUITING
Conditions: Stage III Solid Tumors|Stage IV Solid Tumors
Interventions: DIAGNOSTIC_TEST: Comprehensive liquid molecular panel test|OTHER: EORTC QLQ-30
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Collection of Serum Samples in Studying Emotional Stress in Patients With Prostate Cancer
Status: COMPLETED
Conditions: Hormone-Resistant Prostate Cancer|Recurrent Prostate Carcinoma|Stage I Prostate Cancer|Stage II Prostate Cancer|Stage IIA Prostate Cancer|Stage IIB Prostate Cancer
Interventions: PROCEDURE: Biospecimen Collection|OTHER: Laboratory Biomarker Analysis|OTHER: Questionnaire Administration
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study to Compare the Pharmacokinetics of Fixed-Dose Combination of Mometasone + Azelastine Nasal Spray to Mometasone and Azelastine Nasal Sprays in Adolescents and Young Adults With Seasonal Allergic Rhinitis
Status: TERMINATED
Conditions: Seasonal Allergic Rhinitis
Interventions: DRUG: Mometasone + Azelastine|DRUG: Mometasone Furoate|DRUG: Azelastine Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Muromonab-CD3 and Cyclosporine in Patients With Giant Cell Myocarditis
Status: COMPLETED
Conditions: Myocarditis
Interventions: DRUG: Muromonab-CD3|DRUG: Cyclosporine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized Double Blind Placebo Control Study of Huang-Chi-Wu-Wu- Tang in Patients With Intracranial Arterial Stenosis
Status: UNKNOWN
Conditions: Intracranial Arterial Stenosis
Interventions: DRUG: Chinese Herb Huang-Chi-Wu-Wu-Tang|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Family Networks Project Study One: An Efficacy Study of Stepping Stones Triple P for Children Under Age Two
Status: COMPLETED
Conditions: Prevent Child Maltreatment
Interventions: BEHAVIORAL: Stepping Stones Triple P|OTHER: BabyNet Services As usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Phase 2, Parallel Group, Rollover Study of AKR-501 in Patients With ChronicITP Who Completed 28 Days of Study Treatment in Protocol 501-CL-003
Status: COMPLETED
Conditions: Idiopathic Thrombocytopenic Purpura
Interventions: DRUG: Blinded (placebo)|DRUG: Open Label (Avatrombopag tablets)|DRUG: Blinded (Avatrombopoag tablets)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: (Anti-Ribosomal P Protein,Anti-U1 RNP, Anti-Nucleosome and Anti-ds DNA Antibodies) and Relation to Depression and Anxiety in SLE
Status: RECRUITING
Conditions: Systemic Lupus Erythematosus
Interventions: DIAGNOSTIC_TEST: Anti-Ribosomal P Protein,Anti-U1 RNP, Anti-Nucleosome and Anti-Double Strad DNA Antibodies
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Clinical Transformation of Organoid Model to Predict the Efficacy of GC in the Treatment of Intrahepatic Cholangiocarcinoma
Status: NOT_YET_RECRUITING
Conditions: Organoids|Intrahepatic Cholangiocarcinoma
Interventions: DEVICE: gemcitabine + cisplatin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Cone Beam Computed Tomography Versus Intraoral Digital Radiography in Detection and Measurements of Simulated Periodontal Bone Defects
Status: UNKNOWN
Conditions: Periodontal Bone Defects Will be Detected and Measured by 2 Techniques CBCT and Intraoral Digital Radiography to Compare the Accuracy of These Techniques
Interventions: RADIATION: CBCT and intraoral digital radiography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Alisertib for Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Acute Myelogenous Leukemia
Interventions: DRUG: Cytarabine|DRUG: Idarubicin|DRUG: Alisertib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Various Electrotherapy Methods in Treating People With Cervical Spine Pain Syndrome.
Status: UNKNOWN
Conditions: Cervical Spine Syndrome
Interventions: OTHER: Kinesiotherapy combined with electrotherapy (Convenctional TENS method).|OTHER: Kinesiotherapy combined with electrotherapy (Pseudo-acupuncture TENS method).|OTHER: Kinesiotherapy combined with electrotherapy (Trabert ultrastimulation method)|OTHER: Kinesiotherapy combined with placebo electrotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Entacapone on Bodyweight Loss in Obese Population
Status: UNKNOWN
Conditions: Obesity
Interventions: DRUG: Entacapone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized, Controlled Trial Comparing the Effectiveness of Sedation-Epidural Anesthesia to Spinal Anesthesia in Outpatient Hip or Knee Arthroplasty.
Status: RECRUITING
Conditions: Knee Injuries and Disorders|Hip Injuries|Anesthesia
Interventions: PROCEDURE: Spinal anesthesia|PROCEDURE: Sedation epidural anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Remifentanil and Propofol Versus Fentanyl and Midazolam for Sedation During Therapeutic Hypothermia. A Randomised, Controlled Trial
Status: COMPLETED
Conditions: Hypothermia
Interventions: DRUG: remifentanil and propofol|DRUG: fentanyl and midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Assess Safety and Efficacy of Vilaprisan in Subjects With Uterine Fibroids (ASTEROID 3)
Status: TERMINATED
Conditions: Uterine Fibroids
Interventions: DRUG: Vilaprisan (BAY1002670)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Extraarticular Distal Radius Fractures, X-fix or Volar Fixation
Status: COMPLETED
Conditions: Dorsally Displaced Intraarticular Distal Radius Fractures|Age 50 - 74 for Females or 60-74 for Males|Low Energy Trauma
Interventions: PROCEDURE: External fixation|PROCEDURE: Volar plate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Effects of Sutures on Results of Palate Surgery for Obstructive Sleep Apnea
Status: COMPLETED
Conditions: Obstructive Sleep Apnea
Interventions: PROCEDURE: uvulopalatopharyngoplasty with or without sutures
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fractionated Stereotactic Radiotherapy vs. Single Session Radiosurgery in Patients With Larger Brain Metastases
Status: RECRUITING
Conditions: Cerebral Metastases of Solid Cancers
Interventions: RADIATION: Radiosurgery|RADIATION: Fractionated stereotactic radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect on Teeth and Gum Cleaning in Patients With Gum and Kidney Disease
Status: COMPLETED
Conditions: Renal Insufficiency Chronic|Chronic Periodontitis
Interventions: OTHER: Scaling and Root planing
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study in Healthy Volunteers to Assess the Relative Bioavailability and Tolerability of Two Crenezumab Formulations Following Administration of a Single Subcutaneous Dose
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: Crenezumab|DRUG: Crenezumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Safety & Tolerability of NOV140101(IDX-1197) in Patients With Advanced Solid Tumors
Status: COMPLETED
Conditions: Advanced Solid Tumors
Interventions: DRUG: NOV140101 (IDX-1197)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cytisine for Smoking Cessation
Status: RECRUITING
Conditions: Tobacco Use Disorder|Alcohol Use Disorder|Smoking Cessation
Interventions: DRUG: Cytisine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 2: VVN461 Ophthalmic Solution for Post -Operative Ocular Inflammation After Cataract Surgery
Status: COMPLETED
Conditions: Inflammation
Interventions: DRUG: VVN461 Ophthalmic Solution 1.0%|DRUG: VVN461 Ophthalmic Solution 0.5%|DRUG: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Laparoscopic Proximal Gastrectomy and Laparoscopic Total Gastrectomy
Status: COMPLETED
Conditions: Gastric Cancer
Interventions: PROCEDURE: Laparoscopic proximal gastrectomy|PROCEDURE: Laparoscopic total gastrectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of Etoposide-based Therapy and Hematopoietic Cell Transplantation for Hemophagocytic Lymphohistiocytosis
Status: TERMINATED
Conditions: Hemophagocytic Lymphohistiocytosis
Interventions: DRUG: IST and/or alloHCT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bilateral Versus Monolateral Repetitive Transcranial Stimulation in Depression
Status: COMPLETED
Conditions: Major Depression
Interventions: DEVICE: repetitive transcranial stimulation (rTMS)|DEVICE: unilateral stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of an Eczema Spot Treatment in Providing Eczema Symptoms Relief and Lasting Itch Relief to Affected Skin Area
Status: COMPLETED
Conditions: Dermatitis, Atopic
Interventions: OTHER: Gel Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neuro RX Gamma - Pivotal Phase
Status: SUSPENDED
Conditions: Alzheimer Disease
Interventions: DEVICE: Active Neuro RX Gamma device|DEVICE: Sham Neuro RX Gamma device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Immersive Entertainement Glasses in Magnetic Resonance Imaging (MRI)
Status: COMPLETED
Conditions: Claustrophobia|Magnetic Resonance Imaging (MRI)
Interventions: OTHER: Virtual Immersive Reality Glasses|OTHER: Conventional nurse support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: LDD in Treatment of Femoropopliteal ISR
Status: UNKNOWN
Conditions: Peripheral Artery Disease|In-stent Restenosis
Interventions: DEVICE: balloon dilation only|DEVICE: balloon dilation+local drug delivery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Type of Needle Bevel on Pain Perception in Children During Inferior Alveolar Nerve Block Anesthesia
Status: RECRUITING
Conditions: Anesthesia, Local
Interventions: OTHER: Scalpel blade needles|OTHER: standard blade needles
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Granulocyte-colony Stimulating Factor (G-CSF) and Plerixafor Plus Sorafenib for Acute Myelogenous Leukemia (AML) With FLT3 Mutations
Status: COMPLETED
Conditions: Acute Myelogenous Leukemia|Leukemia
Interventions: DRUG: G-CSF|DRUG: Plerixafor|DRUG: Sorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study of Probiotic Saccharomyces Boulardii Use in Chronic Heart Failure Patients. Estudo PROICA
Status: COMPLETED
Conditions: Heart Failure
Interventions: DRUG: Saccharomyces boulardii
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study About How Well TAK-279 Works and Its Safety in Participants With Moderate-to-severe Plaque Psoriasis During 52 Weeks of Treatment
Status: RECRUITING
Conditions: Plaque Psoriasis
Interventions: DRUG: TAK-279|DRUG: Placebo|DRUG: Apremilast
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Physiological Dead Space Measured by Volumetric Capnography in BiPAP and APRV .
Status: UNKNOWN
Conditions: Ventilation Therapy; Complications
Interventions: DEVICE: APRV ventilation mode|DEVICE: BIPAP ventilation moood
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy of Free Versus Low Residue Diet as Preparation for Screening Colonoscopy
Status: TERMINATED
Conditions: Colorectal Cancer|Colon Polyp|Colon Adenoma
Interventions: OTHER: Free diet|OTHER: Three days low residue diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparison of Microtrauma in Urethra After Usage of Different Catheters
Status: TERMINATED
Conditions: Hematuria
Interventions: DEVICE: LoFric|DEVICE: SpeediCath|DEVICE: SpeediCath Compact Male
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness and Feasibility of a Home-based Exercise Program for Adolescents With Juvenile Idiopathic Arthritis
Status: UNKNOWN
Conditions: Juvenile Idiopathic Arthritis|Juvenile Arthritis|Juvenile Rheumatoid Arthritis
Interventions: BEHAVIORAL: Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Different Preloads for Prevention of Hypotension in Patients Undergoing Elective CS Under Intrathecal Anesthesia
Status: UNKNOWN
Conditions: Hypotension Drug-Induced
Interventions: DRUG: Ringer|DRUG: Voluven
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Physiological Study to Determine the Enteral Threonine Requirements in Infants Aged 1 to 6 Months
Status: TERMINATED
Conditions: Surgical Infants on NG/NJ/J/G-tube Feeds|Tracheoesophageal Fistula|Pierre-Robin Syndrome|Diaphragmatic Hernia
Interventions: DIETARY_SUPPLEMENT: Amino Acid: Threonine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Using OCZ103-OS in Patients With Unresectable and Locally Recurrent or Metastatic Colorectal Cancer Undergoing Standard Chemotherapy
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: OCZ103-OS [pentamidine bis(2-hydroxyethanesulfonate)], mFOLFOX6 or FOLFIRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Enteric-coated Mycophenolate Sodium (EC-MPS) in Comparison to Mycophenolate Mofetil (MMF) in de Nove Heart Patients
Status: COMPLETED
Conditions: Heart Transplantation
Interventions: DRUG: Enteric-coated Mycophenolate Sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Selecting Insulin Analogs for Closed-Loop Control Using Multiplex Pharmacokinetic Profiling
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: OTHER: Multiplex pharmacokinetic profiling|OTHER: Continuous insulin monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Performance of CAD/CAM Milled and 3D-printed Full-arch Implant-supported Provisionals Restorations
Status: RECRUITING
Conditions: Edentulous Jaw|Dental Prosthesis Complication|Dental Prosthesis Failure
Interventions: DEVICE: 3D- printed Full-arch Implant-supported Provisionals Restorations|DEVICE: CAD/CAM-milled Full-arch Implant-supported Provisionals Restorations
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Medtronic SCORE Study - Study of Curette Use for Obtaining Restoration of Vertebral Body Anatomy in Balloon Kyphoplasty
Status: COMPLETED
Conditions: Vertebral Body Compression Fractures (VCFs)
Interventions: DEVICE: Kyphon® Curette
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Signals Electrophysiological Measured by Intelligent Textiles
Status: TERMINATED
Conditions: Healthy
Interventions: DEVICE: test of sensors for somnonaute device|DEVICE: test of sensors for uronaute device|DEVICE: test of sensors for toconaute device|DEVICE: test of sensors for neuronaute device|DEVICE: test of sensors for cardioskin device
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Evaluation of a Model for the Early Diagnosis of Colorectal Cancer by the Detection of 5-hydroxymethylcytosine (5-hmC) in Plasma Cell-free DNA to the Community Colorectal Cancer Screening Program
Status: RECRUITING
Conditions: Colorectal Cancer|Colorectal Neoplasms
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: An Implant for Hearing Loss Due to Removal of Neurofibromatosis 2 Tumors
Status: COMPLETED
Conditions: Neurofibromatosis 2
Interventions: DEVICE: Penetrating auditory brainstem implant
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Continuous Bupivacaine Infusion Following Colonic Surgery
Status: WITHDRAWN
Conditions: Abdominal Surgery
Interventions: DRUG: Bupivacaine|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Identification of Complete Lymph Node Removal by Application of Near Infrared Fluorescence Imaging in Laparoscopic and Robotic Gastrectomy
Status: COMPLETED
Conditions: Gastric Cancer
Interventions: PROCEDURE: Near infrared fluorescence imaging during laparoscopic or robotic gastrectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Topical Cyclosporine A for Treatment and Prevention of Graft Rejection in Corneal Grafts With Previous Rejection Episodes
Status: COMPLETED
Conditions: Endothelial Graft Rejection
Interventions: DRUG: Sandimmune|DRUG: Artelose
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose:
Clinical trial: Regadenoson and Adenosine
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DRUG: Regadenoson central -central|DRUG: Regadenoson peripheral - peripheral|DRUG: Regadenoson central - peripheral|DRUG: Regadenoson peripheral - central|DRUG: Adenosine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Modified BFM-95 Regimen as First-Line Chemotherapy in Adults With T- Lymphoblastic Lymphoma
Status: RECRUITING
Conditions: Lymphoma, Lymphoblastic
Interventions: DRUG: induction phase1|DRUG: induction phase2|DRUG: protocol M|DRUG: maintenance therapy|DRUG: reinduction phase1|DRUG: reinduction phase2|DRUG: Intrathecal (IT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Image Based Brachytherapy in Locally Advanced Cervical Cancers - a Randomized Controlled Trial
Status: UNKNOWN
Conditions: Cervical Cancer
Interventions: RADIATION: Magnetic Resonance Image based Brachytherapy|RADIATION: Conventional Radiograph based Brachytherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rotator Cuff Tear Severity and Scapular and Rotator Cuff Muscle Activation Patterns
Status: RECRUITING
Conditions: Rotator Cuff Tears|Rotator Cuff Injuries|Shoulder Pain
Interventions: DIAGNOSTIC_TEST: Surface Electromyography (sEMG) Assessment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Patient Controlled Epidural Analgesia Versus Intravenous Patient Controlled Analgesia for Post-Operative Pain Control in Patients Undergoing Elective Liver Resection
Status: ACTIVE_NOT_RECRUITING
Conditions: Liver Cancer|Pain Management
Interventions: OTHER: IV PCA|OTHER: PCEA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigating the Effects of Aerobic and Resistance Training in Vivo on Skeletal Muscle Metabolism in Vitro in Primary Human Muscle Cells (MoTrMyo)
Status: RECRUITING
Conditions: Physical Activity
Interventions: OTHER: Additional Muscle Biopsy Collection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Pain Informed Movement Program in Patients With Post COVID-19 Condition
Status: COMPLETED
Conditions: Post COVID-19 Condition
Interventions: OTHER: Pain Informed Movement program|OTHER: Standard medical care and leaflet education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Xarelto Regulatory Post-Marketing Surveillance
Status: COMPLETED
Conditions: Venous Thromboembolism
Interventions: DRUG: Rivaroxaban (Xarelto, BAY59-7939)|DRUG: Pharmacologic agents (e.g. LMWH/VKA/Fondaparinux/Aspirin and etc.)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Gefitinib Compared With Pemetrexed/Cisplatin in Advanced Non-Small Cell Lung Cancer Patients
Status: UNKNOWN
Conditions: Toxicity|Non-small Cell Lung Cancer
Interventions: DRUG: Gefitinib|DRUG: Pemetrexed|DRUG: Cisplatin or carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Conservative Pulp Therapy of Primary Molars Using TheraCAL
Status: COMPLETED
Conditions: Reversible Pulpitis
Interventions: DRUG: Dual cured resin modified tricalcium silicate cement
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Multi-phosphopeptide Vaccine Plus PolyICLC in Participants With High Risk and Advanced Malignancies
Status: COMPLETED
Conditions: Melanoma
Interventions: BIOLOGICAL: pBCAR3-phosphopeptide|BIOLOGICAL: pIRS2-phosphopeptide|BIOLOGICAL: 2-MpP (pBCAR3-phosphopeptide + pIRS2-phosphopeptide)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT