pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Cardiovascular Risk Reduction Study (Reduction in Recurrent Major CV Disease Events)
Status: COMPLETED
Conditions: Atherosclerosis
Interventions: DRUG: Canakinumab|DRUG: Placebo|DRUG: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Antiarrhythmic Drugs Assessment in Preventing Atrial Fibrillation
Status: UNKNOWN
Conditions: Atrial Fibrillation
Interventions: DRUG: Amiodarone|DRUG: Propafenone|DRUG: Sotalol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exercise Following Bariatric Surgery for Severe/Morbid Obesity (EFIBAR)
Status: COMPLETED
Conditions: Obesity, Morbid|Bariatric Surgery Candidate
Interventions: OTHER: Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Internet-delivered CBT for Paediatric OCD
Status: ACTIVE_NOT_RECRUITING
Conditions: Obsessive-Compulsive Disorder
Interventions: BEHAVIORAL: Internet-delivered cognitive behavioral therapy (ICBT)|BEHAVIORAL: Cognitive behavioral therapy (CBT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Muscle Protection Effect of Sevoflurane Sedation in Vascular Surgery
Status: COMPLETED
Conditions: Vascular Surgery
Interventions: DRUG: maintenance of anaesthesia with propofol|DRUG: maintenance of anaesthesia with sevoflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of SPARC1310 in Seasonal Allergic Rhinitis
Status: COMPLETED
Conditions: Seasonal Allergic Rhinitis
Interventions: DRUG: SPARC Placebo|DRUG: SPARC1310 I|DRUG: SPARC1310 II|DRUG: SPARC1310 III
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating Intra-articular Injection of Axolotl Ambient Compared to Saline in Subjects With Ankle Osteoarthritis
Status: TERMINATED
Conditions: Ankle Osteoarthritis
Interventions: BIOLOGICAL: Axolotl Ambient|DRUG: "Drug/Placebo: 0.9% Normal Saline"
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Assessment of Next Science Wound Gels in Healing Below the Knee Amputation Surgical Wound Compared to SOC
Status: WITHDRAWN
Conditions: Surgical Wound|Surgical Site Infection|Surgical Wound Infection|Amputation Stump; Infection|Surgical Incision
Interventions: DEVICE: Next Science Wounds Gels
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Talazoparib and Thoracic RT for ES-SCLC
Status: RECRUITING
Conditions: Lung Cancer|Small-Cell Lung Cancer
Interventions: OTHER: Talazoparib in Combination with Low Dose Radiotherapy (RT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Hyperbaric Oxygenation Therapy on Adaptive, Aberrant and Stereotyped Behaviors in Children With Autism
Status: UNKNOWN
Conditions: Autism
Interventions: PROCEDURE: Hyperbaric Oxygenation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Effect of Intravenous Magnesium on Postoperative Sore Throat After Thyroidectomy
Status: COMPLETED
Conditions: Thyroid Neoplasms
Interventions: DRUG: Magnesium Sulfate|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Essential Connections: Hospital to Community Impacting Malnutrition Outcomes in Older Adults
Status: NOT_YET_RECRUITING
Conditions: Malnutrition; Protein
Interventions: DIETARY_SUPPLEMENT: Nutrition care by RDN, medical nutrition therapy -stepped wedge cluster-randomized trial design. Everyone gets the intervention so no arms.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Augmented Versus Routine Approach to Giving Energy Trial
Status: COMPLETED
Conditions: Critical Illness
Interventions: DIETARY_SUPPLEMENT: TARGET protocol EN 1.5 kcal/mL|DIETARY_SUPPLEMENT: TARGET protocol EN 1.0 kcal/mL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Thalidomide in Mucosa Associated Lymphoid Tissue (MALT) Lymphoma Patients
Status: COMPLETED
Conditions: MALT Lymphoma
Interventions: DRUG: Thalidomide, Pharmion
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study of Filtrum-STI in Children With Viral Gastroenteritis
Status: UNKNOWN
Conditions: Viral Gastroenteritis
Interventions: DRUG: Filtrum-STI (lignin hydrolytic)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: External Control, Observational, Retrospective Study Comparing Pralsetinib to Best Available Therapy in Patients With RET-Fusion Positive NSCLC
Status: UNKNOWN
Conditions: RET-fusion Non Small Cell Lung Cancer|Lung Neoplasm|Carcinoma, Non-Small-Cell Lung|Respiratory Tract Neoplasms|Thoracic Neoplasms|Neoplasms by Site|Neoplasms|Lung Diseases|Respiratory Tract Diseases|Carcinoma, Bronchogenic|Bronchial Diseases|Head and Neck Neoplasms|Carcinoma|Neoplasms by Histologic Type|Neoplasms, Germ Cell and Embryonal|Neoplasms, Nerve Tissue|Metastatic Non Small Cell Lung Cancer
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Comparison of the VBM Intubating Laryngeal Tube and the I-Gel
Status: COMPLETED
Conditions: Airway Management
Interventions: DEVICE: VBM Intubating Laryngeal Tube|DEVICE: I-Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pregabalin (Lyrica) for the Treatment of Restless Legs Syndrome
Status: WITHDRAWN
Conditions: Restless Legs Syndrome
Interventions: DRUG: Pregabalin (Lyrica)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing Intrathecal Morphine and Intraoperative Lidocaine Infusion to Epidural Anesthesia With Postoperative PCA for Patients Undergoing Exploratory Laparotomy
Status: TERMINATED
Conditions: Cancer Debulking|Enlarged Uterus|Fibroid Uterus|Adnexal Mass
Interventions: DRUG: Bupivacaine|DRUG: Morphine|DRUG: Lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Efficacy of Antiadhesive Barrier GUARDIX-FL for Women After Laparoscopic Cystectomy
Status: UNKNOWN
Conditions: Genital Diseases, Female
Interventions: DEVICE: Guardix-FL|DEVICE: Interceed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: First-in-Human (FIH) Clinical Study of NM8074 in Healthy Adult Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: NM8074|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase III Double-blind, Placebo-controlled Study of AZD1222 for the Prevention of COVID-19 in Adults
Status: COMPLETED
Conditions: COVID-19|SARS-CoV-2
Interventions: BIOLOGICAL: AZD1222|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Sublingual and Transdermal Administration of Nitroglycerin for Coronary CT Angiography on Image Quality
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DRUG: Nitroglycerin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Lactobacillus Reuteri DSM 17938 Versus Placebo in the Treatment of Infantile Colic
Status: COMPLETED
Conditions: Colic
Interventions: BIOLOGICAL: Biogaia L. reuteri DSM 17938|BIOLOGICAL: Probiotic Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Inspiratory Muscle Training in Allogeneic Hematopoietic Stem Cell Transplantation Recipients
Status: COMPLETED
Conditions: Allogeneic Hematopoietic Stem Cell Transplantation
Interventions: DEVICE: Inspiratory muscle training|DEVICE: Sham inspiratory muscle training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Multiple Family Narrative Therapy for Chinese Families of Children With Dyslexia
Status: COMPLETED
Conditions: Dyslexia|Special Education|Special Needs Children
Interventions: BEHAVIORAL: Multiple Family Narrative Therapy (MFNT)|BEHAVIORAL: School services for families of children with Dyslexia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of Mirikizumab (LY3074828) in Pediatric Participants With Moderately to Severely or Active Ulcerative Colitis
Status: RECRUITING
Conditions: Ulcerative Colitis
Interventions: DRUG: Mirikizumab IV|DRUG: Mirikizumab SC
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cognitive Enhancement and Relapse Prevention in Cocaine Addiction
Status: COMPLETED
Conditions: Cocaine Addiction
Interventions: DRUG: Seromycin (D-cycloserine, DCS)|DRUG: Placebo|BEHAVIORAL: Computerized Cognitive Behavioral Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Metabolic Effects of Consuming Carbohydrate With Different Protein Types
Status: COMPLETED
Conditions: Metabolic Diseases
Interventions: OTHER: White rice|OTHER: Rice with chicken breast|OTHER: Rice with fish|OTHER: Rice with egg white|OTHER: Rice with beancurd
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study to Evaluate the Bioequivalence of a Test Tablet Formulation of Metformin HCl (1000 mg), Compared to an Equivalent Dose of a Commercially Available Reference Drug Product (Glucophage®, Bristol-Myers Squibb Company) in Fed, Healthy, Adult Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Metformin HCl
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose:
Clinical trial: A Study of Acalabrutinib and Vistusertib in Subjects With Relapsed/Refractory B-cell Malignancies
Status: TERMINATED
Conditions: DLBCL|Richter Syndrome
Interventions: DRUG: acalabrutinib|DRUG: vistusertib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cross-Sectional Study of Oral Health in Patients After Parotid-Sparing Radiation Therapy for Head and Neck Cancer
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: PROCEDURE: Saliva Sample
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Montmorillonite Power or Loperamide on the Pharmacokinetics of Pyrotinib in Healthy Subjects
Status: COMPLETED
Conditions: HER2-positive Recurrent / Metastatic Breast Cancer
Interventions: DRUG: pyrotinib tablet|DRUG: Montmorillonite Power|DRUG: Loperamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Spinal Pain and Autonomic Responses to Chiropractic Care
Status: COMPLETED
Conditions: Neck Pain
Interventions: OTHER: Stretching and Spinal manipulative therapy|OTHER: Stretching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Immature Permanent Teeth With Three Different Pulp Capping Materials With Partial Pulpotomy
Status: COMPLETED
Conditions: Caries, Dental
Interventions: PROCEDURE: Partial Pulpotomy|DRUG: Pulp Capping Agents
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of Chemotherapy Followed by Radiation Therapy to Treat Endometrial Cancer
Status: UNKNOWN
Conditions: Endometrial Cancer
Interventions: DRUG: Docetaxel|DRUG: Cisplatin|RADIATION: Radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pharmacokinetics Study of the Effects of GSK2118436 on Warfarin, the Effects of Ketoconazole and Gemfibrozil on GSK2118436, and the Effects of Repeat Doses of GSK2118436 in Subjects With BRAF Mutant Solid Tumors
Status: COMPLETED
Conditions: Cancer
Interventions: DRUG: Warfarin|DRUG: Ketoconazole|DRUG: Gemfibrozil|DRUG: GSK2118436 150mg|DRUG: GSK2118436 75mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Great Saphenous Vein Sparing Segmental Radiofrequency Ablation in Varicose Veins Patients
Status: COMPLETED
Conditions: Varicose Veins|Varicose Veins of Lower Limb
Interventions: PROCEDURE: GSV radiofrequency ablation with concomitant phlebectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Cognitive Strategies for Weight Loss
Status: RECRUITING
Conditions: Obesity
Interventions: BEHAVIORAL: Standard Behavioral Weight Loss Intervention|BEHAVIORAL: PREVENT Behavioral Weight Loss Intervention|BEHAVIORAL: PROMOTE Behavioral Weight Loss Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Radiation Therapy Plus Fludarabine in Treating Patients With Locally Advanced Cancer of the Mouth, Pharynx, or Larynx
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: DRUG: Fludarabine Phosphate|RADIATION: Radiation Therapy (RT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pharmacokinetic Study of Actinomycin-D and Vincristine in Children With Cancer
Status: UNKNOWN
Conditions: Cancer
Interventions: DRUG: Actinomycin-D|DRUG: Vincristine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: New Maneuver to Facilitate Fiberoptic Intubation for Difficult Airway
Status: COMPLETED
Conditions: Anticipated Difficult Airway
Interventions: OTHER: Lingual Traction|OTHER: Sham|DEVICE: Fiberoptic Intubation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Levobupivacaine and Postoperative Pain Relief
Status: COMPLETED
Conditions: Postoperative Pain|Inguinal Hernia Unilateral
Interventions: DRUG: Instillation of levobupivacaine in surgical wound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Performance Evaluation of the Enlite Glucose Sensor to Support a Full 144 Hours(6Days) of Use
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus|Type 2 Diabetes Mellitus
Interventions: DEVICE: Enlite Sensor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Prevention and Intervention of Neck Pain in Swiss Office-Workers
Status: COMPLETED
Conditions: Neck Pain|Headache|Musculoskeletal Diseases|Adherence, Patient|Absenteeism|Workplace|Health Promotion|Ergonomics|Efficiency|Presenteeism|Occupational Health|Surveys and Questionnaires|Adult|Exercise Therapy|Work Performance
Interventions: OTHER: Multi-component intervention|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of the BARD® True™ Flow Valvuloplasty Perfusion Catheter for Aortic Valve Dilatation
Status: COMPLETED
Conditions: Aortic Valve Stenosis
Interventions: DEVICE: True™ Flow Valvuloplasty Perfusion Catheter
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Blinded Study of Topical Investigational Lotion Vs. Approved Cream in Treatment of Plaque Psoriasis
Status: COMPLETED
Conditions: Plaque Psoriasis
Interventions: DRUG: Halobetasol Proprionate Lotion 0.05%|DRUG: Halobetasol Proprionate Cream 0.05%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Walnuts on Endothelial Function in Overweight Adults With at Least One Factor of Metabolic Syndrome
Status: COMPLETED
Conditions: Metabolic Syndrome
Interventions: DIETARY_SUPPLEMENT: Walnut Supplementation|DIETARY_SUPPLEMENT: No walnut supplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Intra-Individual Comparison of Sirolimus and Paclitaxel Coated Stent (FRE-RACE Study)
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DEVICE: Paclitaxel-eluting TAXUS(TM)|DEVICE: Sirolimus eluting Cypher Select(TM)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of Hemp-CBD on Patients With CIPN
Status: UNKNOWN
Conditions: Chemotherapy-induced Peripheral Neuropathy|Colorectal Cancer Stage II|Colorectal Cancer Stage III|Breast Cancer|Ovarian Cancer|Uterine Cancer|Pancreatic Cancer
Interventions: DRUG: Hemp-based CBD|OTHER: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Investigation of the Visual Outcomes and Safety of a Trifocal Intraocular Lens (IOL) in a Korean Population
Status: COMPLETED
Conditions: Cataract|Presbyopia
Interventions: DEVICE: AcrySof IQ PanOptix Multifocal IOL
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of LY3473329 in Adult Participants With Elevated Lipoprotein(a) at High Risk for Cardiovascular Events
Status: COMPLETED
Conditions: Lipoprotein Disorder
Interventions: DRUG: LY3473329|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Peginterferon Alfa-2b Treatment in HBeAg(+) Chronic Hepatitis b Patients Based on Interferon Gene Mutation and Receptor Detection
Status: UNKNOWN
Conditions: Chronic Hepatitis b
Interventions: DRUG: Entecavir or Tenofovir|DRUG: Peginterferon Alfa-2B
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Liraglutide (Saxenda(R)) in Adolescents With Obesity After Sleeve Gastrectomy
Status: COMPLETED
Conditions: Obesity|Status Post Sleeve Gastrectomy
Interventions: DRUG: Liraglutide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Role of Dopaminergic and Noradrenergic Neurotransmission in Value- and Salience-based Decision-Making
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Methylphenidate|DRUG: Reboxetine|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: TAP Block for Open Radical Prostatectomy.
Status: TERMINATED
Conditions: Opioid Consumption|Incidence of Nausea and Vomiting|Postoperative Pain|Assessment of Recovery
Interventions: PROCEDURE: Normal saline via TAP catheters|PROCEDURE: Lidocaine via TAP catheters
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Soleus Pushup Exercise in Type 2 Diabetes Patients
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: OTHER: Soleus Pushup Exercise|OTHER: treadmill walk group 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Panobinostat in Combination With Idarubicin and Cytarabine in Patients Aged 65 Years or Older With Newly Diagnosed Acute Myeloblastic Leukaemia (AML)
Status: COMPLETED
Conditions: Acute Myeloblastic Leukaemia
Interventions: DRUG: panobinostat
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High-intensity Versus Low-intensity Laser Acupuncture in Chronic, Non-specific Low Back Pain
Status: RECRUITING
Conditions: Chronic Nonspecific Low-back Pain
Interventions: DEVICE: high-intensity laser acupuncture and Exercise therapy program|DEVICE: low-intensity laser acupuncture and Exercise therapy program|DEVICE: Sham laser acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Muscle Spasticity Reduction in Children With Cerebral Palsy by Means of Hippotherapy
Status: COMPLETED
Conditions: Neuromuscular Diseases in Children|Cerebral Palsy, Spastic|Spasticity, Muscle
Interventions: OTHER: Hippotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: One-Day Life Skills Workshop for Veterans With TBI, Pain and Psychopathology
Status: COMPLETED
Conditions: Mild Traumatic Brain Injury|Distress-based Psychopathology|Chronic Pain
Interventions: BEHAVIORAL: Acceptance and Commitment Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Early Detection of Cancer Onset Based on Sensing Field Cancerization at the Organ Level in the Alimentary Tract Using an Integrated Stimulated Raman/Scattering Modality for Endoscopic Real-time in Vivo Measurements
Status: RECRUITING
Conditions: Esophageal Adenocarcinoma|Barrett Esophagus|Colorectal Adenoma|Colorectal Polyp|Colorectal Neoplasms|Colorectal Adenocarcinoma|Carcinogenesis
Interventions: DEVICE: SENSITIVE system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Antenatal Corticoid Therapy for Late Preterm Babies
Status: COMPLETED
Conditions: Hyaline Membrane Disease|Transient Tachypnea
Interventions: DRUG: Betamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Donor Stem Cell Transplant in Treating Patients With High Risk Acute Myeloid Leukemia
Status: TERMINATED
Conditions: Adult Acute Megakaryoblastic Leukemia (M7)|Adult Acute Monoblastic Leukemia (M5a)|Adult Acute Monocytic Leukemia (M5b)|Adult Acute Myeloblastic Leukemia With Maturation (M2)|Adult Acute Myeloblastic Leukemia Without Maturation (M1)|Adult Acute Myeloid Leukemia in Remission|Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities|Adult Acute Myeloid Leukemia With Del(5q)|Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)|Adult Acute Myeloid Leukemia With t(16;16)(p13;q22)|Adult Acute Myeloid Leukemia With t(8;21)(q22;q22)|Adult Acute Myelomonocytic Leukemia (M4)|Adult Erythroleukemia (M6a)|Adult Pure Erythroid Leukemia (M6b)|Childhood Acute Erythroleukemia (M6)|Childhood Acute Megakaryocytic Leukemia (M7)|Childhood Acute Monoblastic Leukemia (M5a)|Childhood Acute Monocytic Leukemia (M5b)|Childhood Acute Myeloblastic Leukemia With Maturation (M2)|Childhood Acute Myeloblastic Leukemia Without Maturation (M1)|Childhood Acute Myeloid Leukemia in Remission|Childhood Acute Myelomonocytic Leukemia (M4)|Recurrent Adult Acute Myeloid Leukemia|Recurrent Childhood Acute Myeloid Leukemia|Secondary Acute Myeloid Leukemia|Untreated Adult Acute Myeloid Leukemia|Untreated Childhood Acute Myeloid Leukemia and Other Myeloid Malignancies
Interventions: DRUG: mitoxantrone hydrochloride|DRUG: cytarabine|PROCEDURE: peripheral blood stem cell transplantation|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of a Postoperative Education Programme Based on Swanson's Theory of Caring on the Self-management Behavioural Competence of Elderly Enterostomal Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Enterostomy|Elderly|Self-management|Education
Interventions: BEHAVIORAL: self-management education program
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Does Inclusion of Diaphragmatic Breathing Exercises in Complete Decongestive Therapy Provide Further Benefits in Patients With Breast Cancer Related Lymphedema
Status: COMPLETED
Conditions: Lymphedema, Breast Cancer|Lymphedema of Upper Limb
Interventions: OTHER: Complete Decongestive Therapy|OTHER: Upper extremity exercises combined with diaphragmatic breathing exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Evaluation of a Multi-Component, Rights-Based Sexuality Education Initiative for High School Students
Status: COMPLETED
Conditions: Pregnancy|Sexually Transmitted Diseases
Interventions: BEHAVIORAL: SEI Classroom Curriculum|BEHAVIORAL: Control Classroom Curriculum|BEHAVIORAL: SEI Curriculum + 3 School Components|BEHAVIORAL: Control Curriculum + 1 School Component
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Effect of Liraglutide in Combination With Sulfonylurea (SU) on Blood Glucose Control in Subjects With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: sulfonylurea|DRUG: liraglutide|DRUG: liraglutide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Laser Treatment for Benign Pigmented Lesions by Non-invasive, Cellular Resolution Optical Coherence Tomography
Status: TERMINATED
Conditions: Benign Pigmented Lesions
Interventions: DEVICE: Laser|DEVICE: ApolloVue® S100 Image System|DEVICE: VISIA®
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Phase I/II/III Gene Transfer Clinical Trial of scAAV9.U1a.hSGSH
Status: ACTIVE_NOT_RECRUITING
Conditions: MPS IIIA|Sanfilippo Syndrome|Sanfilippo A|Mucopolysaccharidosis III
Interventions: BIOLOGICAL: ABO-102|DRUG: Adjuvant Immunosuppression (IS) Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Strategy to Prevent the Onset of Clinically-Apparent Rheumatoid Arthritis
Status: TERMINATED
Conditions: Healthy Participants|Rheumatoid Arthritis (RA) Prevention
Interventions: DRUG: Hydroxychloroquine|DRUG: HCQ Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Pembrolizumab Plus Bevacizumab and Chemotherapy for ALK-rearranged NSCLC With Persistent 5'ALK
Status: RECRUITING
Conditions: ALK Gene Mutation|Lung Adenocarcinoma|Immunotherapy
Interventions: DRUG: Pembrolizumab injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Pharmacokinetics of L608 in Healthy Adults
Status: RECRUITING
Conditions: Pulmonary Arterial Hypertension
Interventions: DRUG: L608 Inhalation Solution|DRUG: Placebo solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Psychosexual Impact of Cancer-Related Infertility in Women: Third Party Reproductive Assistance
Status: COMPLETED
Conditions: Cervical Cancer|Endometrial Cancer|Leukemia|Non-Hodgkin's Lymphoma|Uterine Cancer|Vaginal Cancer|Infertility
Interventions: BEHAVIORAL: survey instrument
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of Naloxegol in the Prevention of POI After Cystectomy
Status: UNKNOWN
Conditions: Bladder Cancer|Cystostomy; Complications
Interventions: DRUG: Naloxégol oxalate|DRUG: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Hepatitis B Virus (HBV) Prevention for Homeless at Risk for HBV/Hepatitis C Virus (HCV)/HIV
Status: COMPLETED
Conditions: Hepatitis B|Hepatitis C|HIV|HIV Infections
Interventions: BEHAVIORAL: NCMIT|BEHAVIORAL: SCMIT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effect of Sedation on Eye Movements
Status: COMPLETED
Conditions: Saccadic Eye Movements
Interventions: DRUG: propofol|DRUG: dexmedetomidine|DRUG: Midazolam|DRUG: saline placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Prehabilitation in Prostate Cancer Patients, TelePrehabTrial
Status: RECRUITING
Conditions: Prostate Cancer
Interventions: OTHER: Physical Exercise|OTHER: Pelvic Floor exercise|OTHER: Sexual counseling|DIETARY_SUPPLEMENT: Nutritional supplement|OTHER: Stress management|OTHER: Standard pre-surgical preparation and pt. information.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Effect of Retro Walking Versus Isometric Multi-angular Exercises on Pain and Functional Performance in Knee Osteoarthritis in Geriatric Population
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: OTHER: Multiangular Isometric exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of AVB-S6-500 in Patients With Platinum-Resistant Recurrent Ovarian Cancer
Status: COMPLETED
Conditions: Ovarian Cancer
Interventions: DRUG: AVB-S6-500|DRUG: Paclitaxel (Pac)|DRUG: Pegylated liposomal doxorubicin (PLD)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical and Urgent Colonoscopy Outcomes Using the Pure-Vu® Cleansing System
Status: TERMINATED
Conditions: Lower Gastrointestinal Bleeding|Hemostatic Disorder
Interventions: DEVICE: Pure-Vu Cleansing Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Efficacy and Safety of DEB-BACE Combined With Serplulimab in First-line Treatment of SCLC
Status: NOT_YET_RECRUITING
Conditions: Carcinoma|Small Cell Lung Cancer
Interventions: PROCEDURE: Drug-eluting beads bronchial arterial chemoembolization|DRUG: Serplulimab|PROCEDURE: Intravenous chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GPC3-CAR-T Cells for Immunotherapy of Cancer With GPC3 Expression
Status: RECRUITING
Conditions: Hepatocellular Carcinoma|Immunotherapy|CAR|GPC3 Gene Inactivation|T Cell|Squamous Cell Lung Cancer
Interventions: BIOLOGICAL: GPC3 and/or TGFβ targeting CAR-T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Xpert MTB/RIF Assay for Diagnosis of Tuberculous Meningitis (TBM) in Maharaj Nakorn Chiang Mai Hospital
Status: COMPLETED
Conditions: Tuberculous Meningitis
Interventions: DIAGNOSTIC_TEST: Xpert MTB/RIF
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Harnessing Generativity Among Young Adult Cancer Survivors
Status: COMPLETED
Conditions: Cancer|Young Adults
Interventions: BEHAVIORAL: Writing for others|BEHAVIORAL: Processing + writing for others|BEHAVIORAL: Facts-only writing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Single-case Design to Investigate a Compensatory Brain Game Supporting Goal Management Training Intervention in a Psychiatric Brain Injury Population
Status: NOT_YET_RECRUITING
Conditions: Acquired Brain Injury|Depressive Symptoms|Anxiety|Executive Dysfunction
Interventions: BEHAVIORAL: Compensatory brain game supporting Goal Management Training intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Is Isokinetic Testing an Indicator of Total Knee Arthroplasty
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: DEVICE: isokinetic testing CSMI HUMAC NORM instrument
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SCREENING
Clinical trial: Study of Cisatracurium and Sufentanil Consumption Using a Closed Loop Computer Control Infusion System
Status: UNKNOWN
Conditions: The Intraoperative Effect of Dexmedetomidine on Cisatracurium Infusion Consumption and Its Recovery Index.|Effect of Dexmedetomidine on Sufentanil Consumption.|Quantitative Analysis of Cisatracurium Infusion Requirements, Sufentanil Consumption and Recovery Index in Different Age Groups.
Interventions: DRUG: Effect of dexmedetomidine on cisatracurium and sufentanil consumption|DRUG: Consumption of cisatracurium and sufentanil in different age groups.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Bioequivalence Study of Abiraterone Acetate Coated and Uncoated Tablet Formulations in Healthy Male Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Abiraterone acetate (Treatment A)|DRUG: Abiraterone acetate (Treatment B)|DRUG: Abiraterone acetate (Treatment B)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Relationship Between Evolution of Resting Energy Expenditure and Tumoral Response to Chemotherapy in Patients Suffering From Pancreas Cancer
Status: TERMINATED
Conditions: Metastatic Pancreatic Cancer
Interventions: OTHER: Measure of resting energetic expenditure
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: PARP Inhibitor With CDK4/6 Inhibitor and Endocrine Therapy in HR+/ HER2-Advanced Breast Cancer
Status: RECRUITING
Conditions: Breast Cancer Metastatic
Interventions: DRUG: Fluzoparib|DRUG: Dalpiciclib|DRUG: Fulvestrant/AI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Interaction of Apelin and Angiotensin in the Systemic Circulation
Status: COMPLETED
Conditions: Renin Angiotensin System
Interventions: DRUG: Angiotensin II|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Trial of Docetaxel, Oxaliplatin and Capecitabine (TEX) in Advanced or Metastatic Gastric Cancer
Status: COMPLETED
Conditions: Stomach Neoplasms
Interventions: DRUG: docetaxel, oxaliplatin, capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Extended Release and Immediate Release Febuxostat in Participants With Gout
Status: COMPLETED
Conditions: Gout
Interventions: DRUG: Febuxostat IR|DRUG: Febuxostat XR|DRUG: Febuxostat placebo|DRUG: Colchicine|DRUG: Naproxen|DRUG: Lansoprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of ENV515 Travoprost Extended Release (XR) in Patients With Bilateral Ocular Hypertension or Primary Open Angle Glaucoma
Status: COMPLETED
Conditions: Glaucoma and Ocular Hypertension
Interventions: DRUG: ENV515-3 Travoprost XR|DRUG: ENV515-1 Travoprost XR|DRUG: ENV515-3-2 Travoprost XR
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multicenter Study of Antiarrhythmic Medications for Treatment of Infants With Supraventricular Tachycardia
Status: COMPLETED
Conditions: Supraventricular Tachycardia
Interventions: DRUG: Digoxin|DRUG: Propranolol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Opioid-induced Bowel Dysfunction: Pivotal Assessment of Lubiprostone
Status: COMPLETED
Conditions: Opioid-Induced Bowel Dysfunction
Interventions: DRUG: Lubiprostone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study To Investigate If MRI Scanning Is Effective At Seeing What Hayfever Drugs Do In Nasal Passage.
Status: COMPLETED
Conditions: Seasonal Allergic Rhinitis|Sinusitis
Interventions: DRUG: pseudoephedrine hydrochloride|DRUG: cetirizine hydrochloride
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Nivolumab in Treating Patients With HTLV-Associated T-Cell Leukemia/Lymphoma
Status: COMPLETED
Conditions: Acute Adult T-Cell Leukemia/Lymphoma|Adult T-Cell Leukemia/Lymphoma|Chronic Adult T-Cell Leukemia/Lymphoma|HTLV-1 Infection|Lymphomatous Adult T-Cell Leukemia/Lymphoma|Smoldering Adult T-Cell Leukemia/Lymphoma
Interventions: OTHER: Laboratory Biomarker Analysis|BIOLOGICAL: Nivolumab|OTHER: Pharmacogenomic Study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Intravenous Nutrition in Patients Undergoing Abdominal Surgery
Status: COMPLETED
Conditions: Postoperative Protein Catabolism
Interventions: OTHER: Intravenous nutrition with glucose and amino acids|OTHER: Intravenous nutrition with amino acids
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Haploidentical and Mismatched Unrelated Donors Hematopoietic Stem Cell Transplant
Status: UNKNOWN
Conditions: Hematopoietic Stem Cell Transplant
Interventions: PROCEDURE: transplant from a haplo-identical donor|PROCEDURE: transplant from a non related donor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: JS001 Combined With TP as First-line Treatment for Unresectable or Advanced Small Cell Esophageal Carcinoma
Status: RECRUITING
Conditions: Esophageal Small Cell Carcinoma
Interventions: DRUG: JS001|DRUG: nab-paclitaxel|DRUG: Cisplatin|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Innovative Toilet Seat Test for Patients With Symptoms of Constipation and/or Emptying Disorders
Status: UNKNOWN
Conditions: Constipation
Interventions: DEVICE: Experimental toilet seat|DEVICE: Standard toilet seat
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RotaTeq® and Meningococcus C Vaccine in Healthy Infants (V260-016)
Status: COMPLETED
Conditions: Meningitis, Meningococcal|Rotavirus Infections
Interventions: BIOLOGICAL: RotaTeq®|BIOLOGICAL: NeisVac-C®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Phase I Trial of CC-8490 for the Treatment of Subjects With Recurrent/Refractory High-Grade Gliomas
Status: COMPLETED
Conditions: Glioblastoma|Malignant Gliomas
Interventions: DRUG: CC-8490
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Short and Long-Term Effects of Prebiotic, Probiotic and Synbiotic on Appetite and Dietary Intake
Status: COMPLETED
Conditions: Appetite|Dietary Intake|Body Weight
Interventions: OTHER: Synbiotic test drink|OTHER: Control drink
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Comparison of HF10 Therapy Combined With CMM to CMM Alone in the Treatment of Non-Surgical Refractory Back Pain
Status: UNKNOWN
Conditions: Back Pain
Interventions: DEVICE: HF10 Therapy|OTHER: CMM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Brentuximab Vedotin in Refractory/Relapsed Hodgkin Lymphoma Treated by ICE
Status: COMPLETED
Conditions: Hodgkin Disease
Interventions: DRUG: Brentuximab Vedotin|DRUG: Etoposide|DRUG: Carboplatine|DRUG: Ifosfamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Central Mechanisms That Regulate Glucose Metabolism in Humans
Status: ACTIVE_NOT_RECRUITING
Conditions: Type 2 Diabetes|Glucose Metabolism Disorders|Glucose, High Blood
Interventions: DRUG: Diazoxide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Adjuvant Chemotherapy Combined With Huaier Granule for Treating High-risk Stage II, Stage III Colorectal Cancer
Status: UNKNOWN
Conditions: Colorectal Cancer
Interventions: DRUG: Huaier Granule|DRUG: Oxaliplatin|DRUG: Calcium folinate|DRUG: 5-fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety of EVG+RTV Administered With Other Antiretroviral Agents for the Treatment of HIV-1 Infection
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: EVG|DRUG: RTV|DRUG: ARV regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improving Treatment Personalization of Pulmonary Hypertension Associated With Diastolic Heart Failure
Status: TERMINATED
Conditions: Pulmonary Hypertension|Diastolic Heart Failure|Heart Failure With Preserved Ejection Fraction
Interventions: DRUG: Nebivolol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Measuring Blood Pressure in the Lung Circulation With Sonar Technology (Echo-Doppler)
Status: TERMINATED
Conditions: Pulmonary Arterial Hypertension
Interventions: PROCEDURE: Transthoracic pulmonary doppler recording
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Efficacy of Lansoprazole and Domperidone Combination on Intragastric and Intraesophageal Acidity
Status: COMPLETED
Conditions: Gastroesophageal Reflux Disease
Interventions: DRUG: Lansoprazole/Domperidone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Assess the Effect of 336 Days Exposure of Paractin® on Pain & Disease Progression in Patients Suffering From Osteoarthritis of Knee Joint.
Status: RECRUITING
Conditions: Knee Osteoarthritis (Knee OA)
Interventions: OTHER: Andrographis paniculata [150 mg]|OTHER: Microcrystalline Cellulose (MCC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER