pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Comparing the Safety and Efficacy of Paclitaxel Controlled Release Balloon Catheter in the Treatment of In-stent Restenosis of Coronary Artery Lesion With Paclitaxel Release Coronary Balloon Catheter
Status: UNKNOWN
Conditions: In-stent Restenosis
Interventions: DEVICE: paclitaxel controlled release balloon catheter Vasoguard TM|DEVICE: paclitaxel release coronary balloon catheter SeQuent Please
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Safety and Pharmacokinetics of Isavuconazole in Healthy Chinese Volunteers
Status: COMPLETED
Conditions: Pharmacokinetics of BAL4815|Pharmacokinetics of BAL8728|Healthy Volunteers
Interventions: DRUG: Isavuconazole|DRUG: Isavuconazole (IV)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Ankle Brachial Index Combined With Serum Uric Acid Levels Improve Prediction All Cause Mortality and Cardiovascular Mortality in the Elderly Chinese Population
Status: COMPLETED
Conditions: Ankle Brachial Index
Interventions: DRUG: antiplatelet drugs;statins;antihypertensive drugs
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Quantitative EEG Neurofeedback as an Add-on Therapy For Attention-deficit Hyperactivity Disorder (ADHD)
Status: NOT_YET_RECRUITING
Conditions: ADHD
Interventions: DEVICE: FDA approved medications for ADHD plus Quantitative EEG Neurofeedback|DRUG: FDA approved medications for ADHD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: TMS Related Biomarker Assessments
Status: RECRUITING
Conditions: Schizophrenia Schizoaffective|Schizophrenia
Interventions: DEVICE: active rTMS first, then sham rTMS|DEVICE: sham rTMS first, then active rTMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Milk on Gut Microbiome and Bone Remodeling CTX in Postmenopausal Women
Status: NOT_YET_RECRUITING
Conditions: Menopause
Interventions: OTHER: YesMilkdiet|OTHER: NoMilkdiet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Toxicity Comparison Between Hypofractionated Radiotherapy With HDR Brachytherapy Boost Versus Standard Treatment
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Cancer
Interventions: RADIATION: Hypofraction|RADIATION: Standard
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bipolar RFA Using Twin ICW Electrodes vs. Switching Monopolar RFA for Recurrent HCC
Status: COMPLETED
Conditions: Hepatocellular Carcinoma
Interventions: DEVICE: Bipolar RFA|DEVICE: SM-RFA|DEVICE: Twin internally cooled-wet electrodes|DEVICE: Separable clustered electrodes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessing the Effect of Contact Isolation on Nosocomial Colonization With ESBL-EC in German Hematology/Oncology Wards
Status: UNKNOWN
Conditions: Oncology [See Also, Affected System]|Hematological Disease|Infection Due to ESBL Escherichia Coli
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Prophylactic Pregabalin Treatment Following Spinal Cord Injury
Status: RECRUITING
Conditions: Spinal Cord Injuries|Spinal Cord Diseases
Interventions: DRUG: Pregabalin 75mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Home Versus Hospital Care in Glucose Monitoring of Gestational Diabetes and Mild Gestational Hyperglycemia
Status: COMPLETED
Conditions: Gestational Diabetes Mellitus|Pregestational Diabetes Mellitus|Mild Gestational Hyperglycemia
Interventions: OTHER: Home care|OTHER: Hospital care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Osteoarthritis of the Knee, Inflammation, and the Effect of Adalimumab (OKINADA)
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: DRUG: Adalimumab 40 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Corneal Endothelial Cell Density Changes In Healthy Subjects, When Administered ISV-403 for 5 Days
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Besifloxacin Ophthalmic Suspension 0.6%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: A Study of INS365 Ophthalmic Solution in Patients With Moderate to Severe Dry Eye Disease
Status: COMPLETED
Conditions: Dry Eye Disease
Interventions: DRUG: diquafosol tetrasodium (INS365) ophthalmic solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Dendreon Lymph Node Biopsy in Metastatic Castrate-Resistant Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: Sipuleucel-T|PROCEDURE: Lymph Node Biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: FIM-NL - First-in-Man Study (Netherlands Part) With Sirolimus Coated Modified BX Velocity Stent
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DEVICE: Sirolimus-coated Bx VELOCITY Stent
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose Escalation Study Using Ultra-Hypofractionated, Image-Guided, Intensity-Modulated Radiotherapy in Prostate Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Cancer|Adenocarcinoma
Interventions: RADIATION: Hypofractionated, image-guided, intensity-modulated external beam radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PHIRST-1: Tadalafil in the Treatment of Pulmonary Arterial Hypertension
Status: COMPLETED
Conditions: Pulmonary Hypertension
Interventions: DRUG: tadalafil|DRUG: tadalafil|DRUG: tadalafil|DRUG: tadalafil|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ultra Phonophoresis With a Hyaluronic Acid-Containing Gel on Carpal Tunnel Syndrome Post Mastectomy.
Status: NOT_YET_RECRUITING
Conditions: 30 Patients Will Receive Ultra Phonophoresis With a Hyaluronic Acid-containing Gel 5 Sessions Per Week for 3 w
Interventions: DEVICE: Ultra Phonophoresis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of SLC-0111 and Gemcitabine for Metastatic Pancreatic Ductal Cancer in Subjects Positive for CAIX
Status: TERMINATED
Conditions: Metastatic Pancreatic Ductal Adenocarcinoma
Interventions: DRUG: SLC-0111|DRUG: Gemcitabine Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cardioprotective Effect of Dexmedetomidine in Patients With ST-segment Elevation Myocardial Infarction
Status: UNKNOWN
Conditions: ST-segment Elevation Myocardial Infarction (STEMI)|Percutaneous Coronary Intervention|Cardioprotection
Interventions: DRUG: Dexmedetomidine (DEX)|DRUG: Placebo (Saline)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Branched-chain Amino Acids Supplementation and Resistance Exercise-induced Muscle Damage and Inflammation
Status: SUSPENDED
Conditions: Muscle Damage|Inflammation
Interventions: DIETARY_SUPPLEMENT: BCAA|DIETARY_SUPPLEMENT: Leucine|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Parenting Skills for Mothers With Borderline Personality Disorder: A Newly Developed Group Training Program
Status: COMPLETED
Conditions: Borderline Personality Disorder
Interventions: BEHAVIORAL: Parenting Skills for Mothers with BPD
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Development of a Treatment Prognosis Calculator for the Prevention of Suicide
Status: RECRUITING
Conditions: Suicidal Ideation
Interventions: BEHAVIORAL: Brief Cognitive Behavioral Therapy (BCBT)|BEHAVIORAL: Treatment as usual (TAU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Buccal Film vs IV Palonosetron for Prevention of CINV in Cancer Patients Receiving MEC
Status: UNKNOWN
Conditions: Chemotherapy-induced Nausea and Vomiting
Interventions: DRUG: Palonosetron HCl Buccal Film 0.5 mg|DRUG: IV Palonosetron 0.25 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Compare the Efficacy of Fluticasone Furoate/Vilanterol Inhalation Powder With Usual Inhaled Corticosteroids (ICS)/Long Acting Beta Agonists (LABA) in Persistent Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Fluticasone Furoate|DRUG: Vilanterol|DRUG: Fluticasone propionate|DRUG: Salmeterol|DRUG: Budesonide|DRUG: Formoterol Fumarate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Durvalumab and Tremelimumab With Platinum-based Chemotherapy in Intrahepatic Cholangiocarcinoma (ICC)
Status: TERMINATED
Conditions: Cholangiocarcinoma
Interventions: DRUG: Novel combination of chemotherapy and immunotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability of Repeated Subcutaneous Injections of CAD 106 in Mild Alzheimer's Patients
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: BIOLOGICAL: Placebo|BIOLOGICAL: CAD106
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rituximab for Schizophrenia Spectrum Disorder (RITS-PS-2019)
Status: COMPLETED
Conditions: Schizophrenia Spectrum and Other Psychotic Disorders|Treatment-resistant Schizophrenia
Interventions: DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Establishment of a Decision Aid Tool for Asymptomatic Small Leiomyoma and Analysis of Influencing Factors for Clinical Decision-making Using HIFU
Status: RECRUITING
Conditions: Leiomyoma, Uterine|High-Intensity Focused Ultrasound Ablation|Patients Decision Aids
Interventions: OTHER: Patients Decision Aids
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Closed Loop Mechanical Ventilation and ECMO
Status: COMPLETED
Conditions: Acute Respiratory Distress Syndrome|Cardiogenic Shock
Interventions: DEVICE: Closed Loop Mechanical Ventilation|DEVICE: Conventional Mechanical Ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mood and Influenza Vaccine Response: A Feasibility Trial
Status: COMPLETED
Conditions: Vaccination; Infection
Interventions: OTHER: Positive Affect Intervention|OTHER: Neutral Control Intervention|BIOLOGICAL: Northern Hemisphere Influenza Vaccine 2017/18 (Delivered as part of Standard Care)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Diagnostic Value of the Biofire®in Community Acquired Pneumonia
Status: COMPLETED
Conditions: Pneumonia
Interventions: DIAGNOSTIC_TEST: Conventional Sputum culture|DIAGNOSTIC_TEST: BioFire Pneumonia Panel (BFPP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: DIAGNOSTIC
Clinical trial: Tandem Occlusion After Emergent Stenting in Acute Ischemic Stroke
Status: RECRUITING
Conditions: Acute Stroke|Ischemic Stroke, Acute
Interventions: PROCEDURE: Emergent Stenting
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Suvorexant in the Treatment of Hot Flash-associated Insomnia
Status: COMPLETED
Conditions: Insomnia
Interventions: DRUG: suvorexant|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Evaluation of Chenopodium Formosanum and Fagopyrum Esculentum Extract on Anti-aging Effect
Status: COMPLETED
Conditions: Skin Condition
Interventions: DIETARY_SUPPLEMENT: Placebo drink|DIETARY_SUPPLEMENT: Chenopodium Formosanum and Fagopyrum Esculentum Extract drink
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Virtual Reality Assisted Patient Empowerment: Diagnose ATTR-Amyloidosis And Start Treatment
Status: NOT_YET_RECRUITING
Conditions: Amyloidosis Cardiac|Virtual Reality
Interventions: DEVICE: Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Care of the Ageing Veteran Population: Developing an Evidence Base for the Royal Hospital Chelsea Model of Care
Status: COMPLETED
Conditions: Quality of Life|Aging Well
Interventions: OTHER: Coffee Morning|OTHER: Recruitment Leaflets|OTHER: Consent Form completion|OTHER: Participant Information Sheet|OTHER: New In-Pensioner Resident Information Pack|OTHER: Key Staff Interviews|OTHER: In-Pensioner Resident Interviews|OTHER: ICECAP-A Quality of Life Questionnaire|OTHER: WHOQOL-BREF Quality of Life Questionnaire
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Slow Yogic-Derived Breathing and Respiration and Cardiovascular Variability in Spinal Cord Injury Patients
Status: ENROLLING_BY_INVITATION
Conditions: Spinal Cord Injuries|Slow Breathing
Interventions: BEHAVIORAL: Slow Breathing
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Treatment for Aggression and Agitation in Patients With Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: LY451395|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Open-label Study of Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Auriхim
Status: COMPLETED
Conditions: Lymphoma, Non-Hodgkin|Lymphoma, Follicular
Interventions: DRUG: Aurixim
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Open-Label Study to Evaluate the Long-Term Safety, Tolerability, and Efficacy of OV101 in Individuals With Angelman Syndrome
Status: TERMINATED
Conditions: Angelman Syndrome
Interventions: DRUG: OV101
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study o Evaluate the Safety, Tolerability, and Immunogenicity of MVC-COV1901, CT-COV-21 Sub-study
Status: COMPLETED
Conditions: Covid19 Vaccine
Interventions: BIOLOGICAL: MVC-COV1901(S protein with adjuvant)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Tumor Treating Fields for Locally Advanced NSCLC
Status: RECRUITING
Conditions: Non Small Cell Lung Cancer
Interventions: RADIATION: carboplatin chemotherapy|DEVICE: NovoTTF-200T (TTFields) System|DRUG: Durvalumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Evaluation on Traditional Chinese Medicine Diagnosis and Treatment Program Blocking and Reversing Hepatitis B-related Liver Fibrosis - a Randomized, Controlled, Double-blind, Multi-center Clinical Trial
Status: UNKNOWN
Conditions: Liver Fibrosis|Chronic Hepatitis B
Interventions: DRUG: Fufang Biejia Ruangan Tablet|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of the Buddy-Up Dyadic Physical Activity Program on Health Outcomes of Care Dyads of Dementia: A Pilot Study
Status: COMPLETED
Conditions: Mild Dementia|Moderate Dementia
Interventions: BEHAVIORAL: BUDPA Program|OTHER: Control arm (Usual care)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Lipid Lowering Effect of a Cereal Based Snack Bar With Added Plant Stanol Ester
Status: COMPLETED
Conditions: Hypercholesterolemia|Hyperlipidemias|Dyslipidemias
Interventions: DIETARY_SUPPLEMENT: Plant stanol ester|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Desflurane on Pediatric Acute Respiratory Distress Syndrome After Living Donor Liver Transplant Recipients
Status: NOT_YET_RECRUITING
Conditions: Pediatric Acute Respiratory Distress Syndrome|Desflurane|Biliary Atresia
Interventions: DRUG: desflurane|DRUG: propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: OBDIPHY (OBesity DIgital-PHYsical Care Study)
Status: ACTIVE_NOT_RECRUITING
Conditions: Pediatric Obesity|Obesity|Adolescent Obesity|Lifestyle Risk Reduction|Metabolic Syndrome|Weight Loss
Interventions: BEHAVIORAL: Digital-physical care|BEHAVIORAL: Treatment as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Personalization of Breast Radiotherapy According to Loco-regional Recurrence Risk and Toxicity Probability
Status: NOT_YET_RECRUITING
Conditions: Breast Cancer
Interventions: RADIATION: COHORT A|RADIATION: COHORT B|RADIATION: COHORT C|RADIATION: COHORT D
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Learn About the Effects of the Combination of Elranatamab (PF-06863135) and Iberdomide in Patients With Relapsed or Refractory Multiple Myeloma (MagnetisMM-30)
Status: RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: Elranatamab|DRUG: Iberdomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Percutaneous Electrolysis, Ultrasound-guided Percutaneous Neuromodulation Therapy and Eccentric Exercise in Supraspinatus Tendinopathy.
Status: COMPLETED
Conditions: Supraspinatus Tendinitis
Interventions: OTHER: Therapeutic Percutaneous Electrolysis an neuromodulation|OTHER: Conventional group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Come As You Are - Assessing the Efficacy of a Nurse Case Management HIV Prevention and Care Intervention Among Homeless Youth
Status: ACTIVE_NOT_RECRUITING
Conditions: Behavior, Risk
Interventions: BEHAVIORAL: NCM4HIV|BEHAVIORAL: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: To Compare Safety and Efficacy of Perrigo's Drug Product Compared to an FDA Approved Drug Product in the Treatment of Actinic Keratosis
Status: COMPLETED
Conditions: Actinic Keratosis
Interventions: DRUG: Ingenol Mebutate (Perrigo)|DRUG: Ingenol Mebutate (Reference)|DRUG: Placebo gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study to Substantiate the Use of the Jay Sensitivity Sensor Probe
Status: COMPLETED
Conditions: Dentine Sensitivity
Interventions: OTHER: A01|OTHER: B99|OTHER: M89
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Vitamin D Replacement After Kidney Transplant
Status: ACTIVE_NOT_RECRUITING
Conditions: Kidney Transplantation|Vitamin D Deficiency
Interventions: DIETARY_SUPPLEMENT: vitamin D3|DIETARY_SUPPLEMENT: vitamin D3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Circadian Rhythm Deregulation in Patients With CAPS
Status: NOT_YET_RECRUITING
Conditions: Cryopyrin Associated Periodic Syndrome|Familial Cold Urticaria|Muckle-Wells Syndrome|CINCA Syndrome
Interventions: GENETIC: Genetic analysis of NLRP3|DEVICE: Circadian rhythm measurement|BIOLOGICAL: Saliva sampling|OTHER: Questionnaire|OTHER: AIDAI score|BIOLOGICAL: Blood sampling
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Biopsychosocial Effectiveness of Exercise Trainings in Earthquake Survivors With Post-Traumatic Stress Disorder
Status: NOT_YET_RECRUITING
Conditions: Post-Traumatic Stress Disorder
Interventions: OTHER: Aerobic Exercise (AE) Group|OTHER: Combined Exercise (CE) Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase III, Long-Term, Open-Label, Extension Study of 0.1% Tacrolimus(FK506) Ophthalmic Suspension in Patients With Vernal Keratoconjunctivitis
Status: COMPLETED
Conditions: Keratoconjunctivitis|Conjunctivitis
Interventions: DRUG: FK506
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CTAG Dissection/Trauma Post Marketing Surveillance Japan
Status: COMPLETED
Conditions: Thoracic Aortic Aneurysm|Thoracic Aorta Injury|Thoracic Aortic Dissection
Interventions: DEVICE: Conformable GORE® TAG® Thoracic Endoprosthesis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Electroretinogram: a New Human Biomarker for Smoking Cessation Treatment
Status: TERMINATED
Conditions: Smoking Cessation|Tobacco Use|Tobacco Dependence|Tobacco Use Disorder|Tobacco Smoking|Cigarette Smoking|Nicotine Dependence|Nicotine Use Disorder|Smoking|Smoking, Cigarette
Interventions: BEHAVIORAL: Contingency management
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Randomized Trial Comparing Single vs. Maintenance Fecal Microbiota Transplant for Refractory Crohn's Disease in Children
Status: WITHDRAWN
Conditions: Crohn Disease
Interventions: BIOLOGICAL: Fecal Microbiota Transplantation|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Artificial Tears, Tear Lipids and Tear Film Dynamics
Status: COMPLETED
Conditions: Dry Eye
Interventions: DRUG: Systane Complete PF|DRUG: Refresh Relieva PF|DRUG: Refresh Optive Mega-3 PF|DRUG: CVS Health Lubricant Eye Drop (PG 0.6%)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Short-Course Chemoradiotherapy Followed by Chemotherapy for the Treatment of Resectable Gastric Adenocarcinoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Clinical Stage I Gastric Cancer AJCC v8|Clinical Stage IIA Gastric Cancer AJCC v8|Clinical Stage III Gastric Cancer AJCC v8|Clinical Stage IVA Gastric Cancer AJCC v8|Gastric Adenocarcinoma|Pathologic Stage IB Gastric Cancer AJCC v8|Pathologic Stage II Gastric Cancer AJCC v8|Pathologic Stage IIA Gastric Cancer AJCC v8|Pathologic Stage IIB Gastric Cancer AJCC v8|Pathologic Stage III Gastric Cancer AJCC v8|Pathologic Stage IIIA Gastric Cancer AJCC v8|Pathologic Stage IIIB Gastric Cancer AJCC v8|Pathologic Stage IIIC Gastric Cancer AJCC v8|Postneoadjuvant Therapy Stage I Gastric Cancer AJCC v8|Postneoadjuvant Therapy Stage II Gastric Cancer AJCC v8|Postneoadjuvant Therapy Stage III Gastric Cancer AJCC v8
Interventions: DRUG: Capecitabine|DRUG: Fluorouracil|RADIATION: Radiation Therapy|PROCEDURE: Therapeutic Surgical Procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Safety and PK of Multiple Doses of LT3001 Drug Product and Drug-drug Interaction in Healthy Subjects
Status: UNKNOWN
Conditions: Acute Ischemic Stroke
Interventions: DRUG: LT3001 drug product|DRUG: Placebo|DRUG: Aspirin|DRUG: Clopidogrel|DRUG: Apixaban|DRUG: Dabigatran
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Diaphragm Electrical Activity of Preterm Infants on nCPAP Versus NIHFV
Status: COMPLETED
Conditions: Respiratory Distress Syndrome, Newborn
Interventions: DEVICE: Drager VN500 Ventilator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial on Radical Upfront Surgery in Advanced Ovarian Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Ovarian Cancer
Interventions: PROCEDURE: PDS (Primary Debulkdung Surgery)|PROCEDURE: 6 cycles of standard chemotherapy|PROCEDURE: Timing of surgery after 3 cycles of standard NACT, IDS|PROCEDURE: IDS|DRUG: 3 cycles of standard chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prednisone in Chronic Rhinosinusitis Without Nasal Polyps
Status: UNKNOWN
Conditions: Sinusitis|Chronic Rhinosinusitis
Interventions: DRUG: Prednisone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Toward a Computationally-Informed, Personalized Treatment for Hallucinations
Status: RECRUITING
Conditions: Hallucinations, Auditory|Psychosis
Interventions: DRUG: Rivastigmine Transdermal System|DRUG: Scopolamine|DRUG: Placebo Patch|DRUG: Placebo Patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: AZD0486 as Monotherapy in B-cell Acute Lymphoblastic Leukaemia
Status: RECRUITING
Conditions: B-cell Acute Lymphoblastic Leukemia (B-ALL)
Interventions: DRUG: AZD0486
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating Neostigmine Effect on Reducing Gastric Residual Volume as Compared With Metoclopramide and Ondansetron
Status: COMPLETED
Conditions: Delayed Gastric Emptying
Interventions: DRUG: Neostigmine|DRUG: Ondansetron 8mg|DRUG: Metoclopramide Injection|OTHER: Enteral feeding nutrition|OTHER: Sequential Organ Failure Assessment (SOFA) score
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Rituximab Maintenance Treatment of Newly Diagnosed Follicular Lymphoma After BR or RCHOP or R2: a Multicenter Clinical Study
Status: UNKNOWN
Conditions: Follicular Lymphoma
Interventions: DRUG: BR for 6 cycles +R for 8 cycles|DRUG: RCHOP for 6 cycles +R for 8 cycles|DRUG: R2 for 6 cycles + R2 maintenance
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Effectiveness of the Simple Puncture Compared to the Incision of an Abscess on the piLOnidal Sinus
Status: NOT_YET_RECRUITING
Conditions: Pilonidal Cyst
Interventions: PROCEDURE: puncture|PROCEDURE: incision of the abscess
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Peritumoral Injection of Immature Dendritic Cells to Irradiated Skin Metastases of Solid Tumors
Status: TERMINATED
Conditions: Cancer of Skin|Solid Tumors
Interventions: PROCEDURE: Immunotherapy treatment for solid tumors
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Biomarkers of Alcohol After an Experimental Administration of Alcohol Simulating a "Binge Drinking" Episode
Status: UNKNOWN
Conditions: Binge Drinking|Alcohol-Related Disorders
Interventions: OTHER: Alcohol
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study in Toddlers to Demonstrate Non-inferiority of GSK Biologicals' Hib-MenC & to Evaluate Persistence up to 5 Years.
Status: COMPLETED
Conditions: Haemophilus Influenzae Type b|Neisseria Meningitidis
Interventions: BIOLOGICAL: Haemophilus influenzae type b and meningococcal serogroup C (vaccine)|BIOLOGICAL: Priorix™|BIOLOGICAL: Hiberix™|BIOLOGICAL: Meningitec™
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study to Evaluate TV-46000 as Maintenance Treatment in Adult and Adolescent Participants With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: TV-46000|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Amnion Wound Covering for Enhanced Wound Healing
Status: COMPLETED
Conditions: Burns|Wound of Skin|Skin Wound
Interventions: DRUG: Amnion Membrane Powder|PROCEDURE: SOC Wound Covering
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized Trial to Study the Safety and Efficacy of EGF Cancer Vaccination in Late-stage (IIIB/IV) Non-small Cell Lung Cancer Patients
Status: TERMINATED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: BIOLOGICAL: Therapeutic EGF Vaccine (Cyclophosphamide and the recombinant human rEGF-P64K/Montanide ISA 51 vaccine)
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose:
Clinical trial: Electronic Cigarettes as a Harm Reduction Strategy Among Patients With COPD
Status: COMPLETED
Conditions: COPD
Interventions: OTHER: E-cigarette (EC)|OTHER: Nicotine Replacement Therapy (NRT)|BEHAVIORAL: Smoking Harm Reduction Counseling Sessions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Escitalopram for the Prevention of PEGASYS-associated Depression in Hepatitis C Virus-infected Patients
Status: COMPLETED
Conditions: Depression
Interventions: DRUG: Escitalopram|DRUG: Placebo|DRUG: Peginterferon alfa-2a|DRUG: Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study Evaluating Inhaled AeroLEF (Liposome-Encapsulated Fentanyl)in Normal Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: i.v. fentanyl and AeroLEF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Examining the Effectiveness of Wysa for Worry Program
Status: NOT_YET_RECRUITING
Conditions: Anxiety
Interventions: BEHAVIORAL: Wysa for Worry|BEHAVIORAL: App-based Psychoeducation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Dexmedetomidine Versus Midazolam for Intensive Care Sedation of Children
Status: UNKNOWN
Conditions: Sedation
Interventions: DRUG: dexmedetomidine|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Nutritional Transitions to More Plant Proteins and Less Animal Proteins: Understanding the Induced Metabolic Reorientations and Searching for Their Biomarkers (ProVegOmics)
Status: COMPLETED
Conditions: Metabolic Syndrome|Hypertriglyceridemia|Fasting Blood Sugar Above Normal|Lower Than Standard HDL-cholesterol Level|Slightly Elevated Blood Pressure
Interventions: BEHAVIORAL: Diets with either predominantly animal protein sources.|BEHAVIORAL: Diets with predominantly plant protein sources
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Randomized, Double-Blind, Safety and Efficacy Study of RE-021 (Sparsentan) in Focal Segmental Glomerulosclerosis
Status: COMPLETED
Conditions: Focal Segmental Glomerulosclerosis
Interventions: DRUG: RE-021 (Sparsentan)|DRUG: Irbesartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ntraperitoneal Thermal Perfusion Combined With Chemotherapy Versus Chemotherapy
Status: UNKNOWN
Conditions: Advanced Pancreatic Cancer
Interventions: DRUG: cisplatin+Nab-paclitaxel+GEM|DRUG: Nab-paclitaxel+GEM
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vitamin D and Resistance Exercise in Elderly (NUTRIAGINGVitD)
Status: UNKNOWN
Conditions: Aging
Interventions: OTHER: Strength Training and Vitamin D monthly|OTHER: Strength Training and Vitamin D daily|OTHER: Strength Training and no Vitamin D
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Everolimus in Treating Patients With Lymphoma That Has Relapsed or Not Responded to Previous Treatment
Status: COMPLETED
Conditions: Leukemia|Lymphoma|Lymphoproliferative Disorder
Interventions: DRUG: Everolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Maternal Genes and Epimutations: Beckwith-Wiedemann Syndrome & Reproductive Risks
Status: RECRUITING
Conditions: Beckwith-Wiedemann Syndrome
Interventions: GENETIC: WES analysis|GENETIC: whole-genome methylation analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Comparative Double-Blind, Double- Dummy Study of Desloratadine (DL) 5 MG Once Daily, Cetirizine 10 MG Once Daily, and Placebo Once Daily in Patients With Chronic Idiopathic Urticaria (Study P03735)
Status: COMPLETED
Conditions: Urticaria
Interventions: DRUG: desloratadine|DRUG: placebo|DRUG: cetirizine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Topical Cysteamine for Postinflammatory Hyperpigmentation
Status: UNKNOWN
Conditions: Hyperpigmentation; Postinflammatory
Interventions: DRUG: Topical Cysteamine|DRUG: Topical Vehicle Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Efficacy and Safety of Ranibizumab Injection in Patients With Macular Edema Secondary to Branch Retinal Vein Occlusion (BRAVO)
Status: COMPLETED
Conditions: Macular Edema|Retinal Vein Occlusion
Interventions: DRUG: Ranibizumab injection 0.3 mg|DRUG: Ranibizumab injection 0.5 mg|DRUG: Sham injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of PF-06940434 in Patients With Advanced or Metastatic Solid Tumors.
Status: ACTIVE_NOT_RECRUITING
Conditions: Squamous Cell Carcinoma of the Head and Neck|Renal Cell Carcinoma|Ovarian Cancer|Gastric Cancer|Esophageal Cancer|Lung Squamous Cell Carcinoma|Pancreatic Cancer|Bile Duct Cancer|Endometrial Cancer|Melanoma Cancer|Urothelial Cancer
Interventions: DRUG: PF-06940434|DRUG: PF-06801591
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endogenous GLP-1 Secretion on Islet Function in People With and Without Type 2 Diabetes
Status: COMPLETED
Conditions: Healthy|Type 2 Diabetes
Interventions: BIOLOGICAL: Saline|BIOLOGICAL: Exendin-9,39|BIOLOGICAL: Saline + Intralipid/Heparin|BIOLOGICAL: Exendin-9,39 + Intralipid/Heparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: This Study is Being Performed to Evaluate the Effect of Genasense on the Efficacy and the Safety of Rituximab/Fludarabine Combination Treatment in Previously Untreated Subjects With Chronic Lymphocyctic Leukemia(CLL)
Status: WITHDRAWN
Conditions: Lymphocytic Leukemia
Interventions: DRUG: Genasense® (, oblimersen sodium G3139)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Laser Vaporization of the Prostate: Comparing Between Ejaculatory Preserving and Non-ejaculatory Preserving Technique
Status: RECRUITING
Conditions: Prostatic Hyperplasia
Interventions: PROCEDURE: new technique of ejaculatory preserving laser prostatectomy|PROCEDURE: conventional technique of laser vaporization of the prostate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TAK-114 Single- and Multiple-Dose Phase 1 Study
Status: COMPLETED
Conditions: Clinical Pharmacology
Interventions: DRUG: TAK-114 10 mg capsule|DRUG: TAK-114 matched placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Strengthening Exercise and Activities of Daily Living Instructions for Patients With Lumbar Disc Herniation
Status: COMPLETED
Conditions: Lumbar Disc Herniation
Interventions: OTHER: Strengthening exercises|DRUG: Pharmacological therapy|OTHER: Hot compression|BEHAVIORAL: Activities to daily living instructions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivaelnce Study of Doxycycline Monohydrate 100mg Tablets Under Fed Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Doxycycline monohydrate 100mg tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Study of Multiple Oral Doses of Odanacatib (MK0822) in Healthy Adults (0822-002)
Status: COMPLETED
Conditions: Osteoporosis
Interventions: DRUG: odanacatib|DRUG: Comparator: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Interferon-α1b Combined With Toripalimab and Anlotinib Hydrochloride in Advanced Unresectable Melanoma
Status: NOT_YET_RECRUITING
Conditions: Melanoma
Interventions: DRUG: Recombinant human interferon α1b|DRUG: Toripalimab|DRUG: Anlotinib hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Use of a Probiotic Lozenge in the Treatment of Residual Pockets After Classical Non-surgical Therapy
Status: COMPLETED
Conditions: Periodontitis
Interventions: OTHER: Probiotic tablet- Biogaia|OTHER: Placebo tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of VR and Glass WF Colonoscopy
Status: NOT_YET_RECRUITING
Conditions: Misadventure During Endoscopic Examination
Interventions: DEVICE: Virtual Reality Glasses Group|DEVICE: Glass waterfall
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Two Dose Levels of DFN-15 vs. Placebo in Patients With Migraine Headaches
Status: COMPLETED
Conditions: Migraine
Interventions: DRUG: DFN-15 Dose A (treatment A)|DRUG: DFN-15 Dose B (treatment B)|OTHER: Placebo (treatment C)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intervention With Selution SLR™ Agent Balloon for Endovascular Latent Limus Therapy for Failing AV Fistulas (ISABELLA) Trial
Status: UNKNOWN
Conditions: Arteriovenous Fistula|Dialysis Access Malfunction
Interventions: DEVICE: Selution SLR™ 018 Drug Eluting Balloon
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Alisertib and Combination Chemotherapy in Treating Patients With Gastrointestinal Tumors
Status: COMPLETED
Conditions: Malignant Digestive System Neoplasm
Interventions: DRUG: Alisertib|DRUG: Fluorouracil|OTHER: Laboratory Biomarker Analysis|DRUG: Leucovorin Calcium|DRUG: Oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Panzem NCD to Treat Glioblastoma
Status: COMPLETED
Conditions: Recurrent Glioblastoma Multiforme
Interventions: DRUG: Panzem Nanocrystal Colloidal Dispersion
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ketanserin Effects on Peripheral Temperature and Lactate
Status: UNKNOWN
Conditions: Critical Illness
Interventions: DRUG: Ketanserin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clotting Parameters After Medical Abortion
Status: COMPLETED
Conditions: Abortion Early|Abortion, Complete|Abortion, Second Trimester|Termination of Pregnancy Complicated by Embolism|Venous Thromboses|Venous Thromboembolism|Venous Thromboembolic Disease|Clotting Disorder
Interventions: DIAGNOSTIC_TEST: Thromboelastometry|DIAGNOSTIC_TEST: Clotting Studies|DIAGNOSTIC_TEST: Full Blood Count|DIAGNOSTIC_TEST: Quantitative hCG|DIAGNOSTIC_TEST: Pregnancy Test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Tolerability of BION-1301 in Healthy Volunteers and Adults With IgA Nephropathy (IgAN)
Status: ACTIVE_NOT_RECRUITING
Conditions: IgA Nephropathy
Interventions: DRUG: BION-1301 Single Dose|DRUG: Placebo Single Dose|DRUG: BION-1301 Multiple Doses|DRUG: Placebo Multiple Doses|DRUG: BION-1301 Single Dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Early Detection and Intervention for the Prevention of Psychosis
Status: COMPLETED
Conditions: Schizophrenia|Bipolar Disorder|Depression|Psychotic Disorders
Interventions: DRUG: aripiprazole; fluoxetine; bupropion; sertraline; lamotrigine|BEHAVIORAL: Psychoeducational multifamily group treatment|BEHAVIORAL: Supported employment and education
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Randomized Study in Non-Hodgkin's Lymphoma Patients Carrying Hepatitis B Surface Antigen
Status: COMPLETED
Conditions: Non-Hodgkin's Lymphoma
Interventions: DRUG: Cyclophosphamide Doxorubicin Vincristine Lamivudine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of the Tiger Catheter on Transradial Coronariography: Randomized Compared to JudKins cathETers
Status: COMPLETED
Conditions: Acute Coronary Syndrome
Interventions: DEVICE: Tiger catheter|DEVICE: Judkins catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Combination Chemotherapy and Radiation Therapy in Treating Patients With Locally Advanced Head and Neck Cancer
Status: TERMINATED
Conditions: Head and Neck Cancer
Interventions: BIOLOGICAL: filgrastim|BIOLOGICAL: pegfilgrastim|DRUG: cisplatin|DRUG: docetaxel|DRUG: fluorouracil|PROCEDURE: conventional surgery|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT