pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Randomized Controlled Trial of Bilateral Movement-based Computer Games Training to Improve Motor Function of Upper Limb and Quality of Life in Sub-acute Stroke Patient
Status: COMPLETED
Conditions: Stroke
Interventions: OTHER: Bilateral movement-based computer training|OTHER: Video-directed conventional training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intrathecal Diamorphine Versus Femoral Nerve Block in Primary Total Knee Arthroplasty
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: PROCEDURE: Femoral Nerve Block with levobupivicaine|PROCEDURE: Intrathecal injection of diamorphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Using Multiparametric Flow Cytometry to Detect Peripheral Blood and Bone Marrow Leukaemia Stem Cells for Relapse Prediction in P-AML
Status: NOT_YET_RECRUITING
Conditions: Acute Myeloid Leukemia|Acute Lymphoblastic Leukemia
Interventions: OTHER: MFC for the determination of leukemia stem cell
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Home-based Exercise Therapy for Patients With PAD
Status: RECRUITING
Conditions: Peripheral Arterial Disease (PAD)|Intermittent Claudication
Interventions: BEHAVIORAL: WalkingPad plus Psychological Intervention - PsyWPad Group|BEHAVIORAL: WalkingPad plus Virtual Assistant - CyberWPad Group|BEHAVIORAL: WalkingPad group - Paper WPad Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Perioperative Leucovorin, Oxaliplatin, Docetaxel and S-1 (LOTS) For Locally Advanced Gastric or Gastroesophageal Junction Cancer
Status: RECRUITING
Conditions: Gastric Cancer|Gastric Adenocarcinoma|Effects of Chemotherapy|Toxicity Due to Chemotherapy
Interventions: DRUG: leucovorin, oxaliplatin, docetaxel, S-1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Prospective Pilot Study for the Evaluation of 18F- Fluciclovine PET/MRI in Radio-recurrent Prostate Cancer (RRPC-PET/MRI Study)
Status: WITHDRAWN
Conditions: Prostate Cancer|Prostate Nodule
Interventions: RADIATION: 18F-fluciclovine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of Tenecteplase for Restoration of Function in Dysfunctional Hemodialysis Catheters
Status: COMPLETED
Conditions: Dysfunctional Hemodialysis Catheters
Interventions: DRUG: placebo|DRUG: tenecteplase
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Yangxinshi Pills on the Exercise Tolerance of the Patients With Coronary Heart Disease
Status: UNKNOWN
Conditions: Coronary Heart Disease
Interventions: DRUG: Yangxinshi pill|DRUG: conventional coronary heart disease medicine|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Catatonia: Effectiveness of Transcranial Direct Current Electrostimulation (CATATOES)
Status: NOT_YET_RECRUITING
Conditions: Catatonia
Interventions: DEVICE: Active tDCS|DEVICE: Sham tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Music Therapy in Acute Leukemia Patients With Fatigue
Status: NOT_YET_RECRUITING
Conditions: Acute Myeloid Leukemia|Fatigue
Interventions: OTHER: Music Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Barbed Suture in Single-port Laparoscopic Myomectomy
Status: COMPLETED
Conditions: Uterine Myoma
Interventions: PROCEDURE: Single-port laparoscopic myomectomy|PROCEDURE: Multi-port laparoscopic myomectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Leflunomide in Treating Patients With High-Risk Smoldering Multiple Myeloma
Status: WITHDRAWN
Conditions: Smoldering Plasma Cell Myeloma
Interventions: DRUG: Leflunomide|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rest/Stress Quantification Of Left Ventricular Dyssynchrony By 3D Gated Blood Pool D-SPECT
Status: UNKNOWN
Conditions: Left Ventricular Dyssynchrony
Interventions: DEVICE: 3D Blood-Pool Gated SPECT (BPGS) with a new designed cardiac imaging camera (DSPECT, Spectrum Dynamics®, Ceasaria, Israel)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Triggered Escalating Real-time Adherence (TERA) Intervention
Status: COMPLETED
Conditions: HIV Infections
Interventions: BEHAVIORAL: TERA Intervention (TERA)|BEHAVIORAL: Standard of Care (SOC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study to Evaluate the Efficacy and Safety of Topical MOB015B in the Treatment of Mild to Moderate Distal Subungual Onychomycosis (DSO)
Status: COMPLETED
Conditions: Distal Subungual Onychomycosis
Interventions: DRUG: MOB015B|DRUG: Ciclopirox 80 mg/g
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose:
Clinical trial: Bcl-2 Antisense Oligodeoxynucleotide G3139 and Paclitaxel in Treating Patients With Recurrent Small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer
Interventions: BIOLOGICAL: oblimersen sodium|DRUG: paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oncolytic Adenovirus TILT-123 and Avelumab for Treatment of Solid Tumors Refractory to or Progressing After Anti-PD(L)1
Status: RECRUITING
Conditions: Melanoma|Head and Neck Squamous Cell Carcinoma
Interventions: BIOLOGICAL: TILT-123|DRUG: Avelumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Induction Chemotherapy,Radiochemotherapy, Consolidation Chemotherapy in Preoperative Treatment of Rectal Cancer
Status: UNKNOWN
Conditions: Rectal Cancer
Interventions: DRUG: intensified preoperative chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of the Artifical Intelligence Assisted Registration Versus Conventional Point Based Registration on Cone Beam-computed Tomography (CBCT) With Heavy Metal Artifacts
Status: ACTIVE_NOT_RECRUITING
Conditions: Registration Accuracy
Interventions: OTHER: AI-assisted registration|OTHER: Point-based registration
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Vitamin D and Genetics in Nutritional Rickets
Status: COMPLETED
Conditions: Nutritional Rickets
Interventions: DIETARY_SUPPLEMENT: Vitamin D + Calcium|DIETARY_SUPPLEMENT: Calcium|DIETARY_SUPPLEMENT: Vitamin D2|DIETARY_SUPPLEMENT: Vitamin D3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: L-citrulline and Metformin in Duchenne's Muscular Dystrophy
Status: COMPLETED
Conditions: Duchenne's Muscular Dystrophy (DMD)
Interventions: DRUG: 750 mg metformin and 7.5 g L-citrulline daily p.o.|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Psilocybin-Assisted Therapy for Severe Alcohol Use Disorder
Status: RECRUITING
Conditions: Severe Alcohol Use Disorder
Interventions: DRUG: Psilocybin (high dose)|DRUG: Active placebo (low dose of psilocybin)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Amisulpride Augmentation in Clozapine-unresponsive Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Amisulpride|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Florbetapir F 18 PET Imaging of Beta-amyloid in Parkinson's Disease Patients
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DRUG: florbetapir F 18
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Adjuvants With Intrathecal Bupivacaine for Postoperative Analgesia
Status: NOT_YET_RECRUITING
Conditions: Postoperative Pain
Interventions: DRUG: Dexmedetomidine|DRUG: Midazolam|DRUG: Bupivacain
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Cryoballoon Ablation Versus Medical Therapy in Patients With Heart Failure and Atrial Fibrillation
Status: UNKNOWN
Conditions: Atrial Fibrillation|Heart Failure|Heart Failure With Reduced Ejection Fraction|Heart Failure, Systolic
Interventions: PROCEDURE: Cryoballoon ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Balance Board and Perceptual Motor Therapy in Children With Cerebral Palsy.
Status: RECRUITING
Conditions: Cerebral Palsy
Interventions: OTHER: Balance Board therapy|OTHER: Perceptual Motor therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Protein-energy Oral Supplementation Enriched With Omega-3 Fatty Acids in Cardiac Cachexia
Status: TERMINATED
Conditions: Cardiac Cachexia
Interventions: DIETARY_SUPPLEMENT: Fortimel Extra®|DIETARY_SUPPLEMENT: Fortimel Care®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Non-pharmacological Interventions for Preschoolers With Attention Deficit Hyperactivity Disorder (ADHD)
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: BEHAVIORAL: Training Executive, Attention and Motor Skills (TEAMS)|BEHAVIORAL: Parent support and education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Romidepsin, Ifosfamide, Carboplatin, and Etoposide in Treating Participants With Relapsed or Refractory Peripheral T-Cell Lymphoma
Status: COMPLETED
Conditions: Mycosis Fungoides|Recurrent Anaplastic Large Cell Lymphoma|Recurrent Angioimmunoblastic T-Cell Lymphoma|Recurrent Enteropathy-Associated T-Cell Lymphoma|Recurrent Hepatosplenic T-Cell Lymphoma|Recurrent Peripheral T-Cell Lymphoma, Not Otherwise Specified|Refractory Anaplastic Large Cell Lymphoma|Refractory Angioimmunoblastic T-Cell Lymphoma|Refractory Enteropathy-Associated T-Cell Lymphoma|Refractory Hepatosplenic T-Cell Lymphoma|Refractory Peripheral T-Cell Lymphoma, Not Otherwise Specified
Interventions: DRUG: Carboplatin|DRUG: Etoposide|DRUG: Ifosfamide|DRUG: Romidepsin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 3 Trial in Squamous Non Small Cell Lung Cancer Subjects Comparing Ipilimumab Plus Paclitaxel and Carboplatin Versus Placebo Plus Paclitaxel and Carboplatin
Status: COMPLETED
Conditions: Lung Cancer (NSCLC)
Interventions: BIOLOGICAL: Paclitaxel|BIOLOGICAL: Carboplatin|BIOLOGICAL: Ipilimumab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Safety and Immunogenicity Trial in Adults 65 Years of Age or Over to Prevent Influenza
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: AVX502|BIOLOGICAL: AVX502|BIOLOGICAL: Placebo|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Efficacy of Analgesic Buffering With Sodium Bicarbonate for the Pediatric Dental Patient
Status: WITHDRAWN
Conditions: Pediatric Dentistry
Interventions: DEVICE: Onset Mixing Pen by Onpharma|DEVICE: 2% lidocaine with 1:100,000 epinephrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Mocravimod as Adjunctive and Maintenance Treatment in AML Patients Undergoing Allo-HCT
Status: RECRUITING
Conditions: Adult Acute Myeloid Leukemia
Interventions: DRUG: mocravimod
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Optimal Duration of Voice Rest After Surgery for Benign Vocal Lesions
Status: UNKNOWN
Conditions: Vocal Fold Polyp|Vocal Cord Cyst|Vocal Nodules in Adults
Interventions: BEHAVIORAL: Voice rest
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effect Of Laparoscopic Sleeve Gastrectomy on Vitamin D, Parathormone and Calcium Levels
Status: COMPLETED
Conditions: Bariatric Surgery Candidate|Obesity, Morbid|Vitamin D Deficiency|Calcium Deficiency
Interventions: PROCEDURE: Laparoscopic sleeve gastrectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multifocal Electroretinogram in Normal Egyptian Population
Status: UNKNOWN
Conditions: Retinal Disease|Healthy Population
Interventions: DEVICE: Multifocal electroretinogram (mf-ERG) by electroretinogram device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Pilot Study to Assess Safety and Efficacy of SIR1-365 in Patients With Severe COVID-19
Status: COMPLETED
Conditions: Corona Virus Infection
Interventions: DRUG: SIR1-365|DRUG: Matching Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impacts of Wild Blueberries on Appetite and Weight Regulation
Status: ACTIVE_NOT_RECRUITING
Conditions: Obesity|Weight Loss
Interventions: DIETARY_SUPPLEMENT: Blueberries|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effects of Extended Release (ER) Niacin/Laropiprant, Laropiprant, ER Niacin, and Placebo on Urinary Prostanoid Metabolites in Subjects With High Cholesterol (0524A-075)(COMPLETED)
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DRUG: Comparator: niacin + laropiprant|DRUG: Comparator: niacin|DRUG: Comparator: laropiprant|DRUG: Comparator: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dexmedetomidine in Different Dose Levels as Adjuvant to Bupivacaine-induced Ultrasound-guided Femoral Nerve Block.
Status: COMPLETED
Conditions: Dexmedetomidine|Femoral Nerve Block|Arthroscopic Knee Surgery
Interventions: DRUG: peri-neural dexmedetomidine as adjuvant to bupivacaine in femoral nerve block|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Prasterone (DHEA) for the Treatment of Hypoactive Sexual Desire Disorder (HSDD)
Status: COMPLETED
Conditions: Hypoactive Sexual Desire Disorder
Interventions: DRUG: Placebo Vaginal Insert|DRUG: Prasterone 6.5 mg (0.50%) Vaginal Insert
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Chemothetapy FORFIRINOX in Advanced or Recurrent Extrahepatic Cholangiocarcinoma and Gallbladder Carcinoma
Status: UNKNOWN
Conditions: Cholangiocarcinoma of the Extrahepatic Bile Duct|Gallbladder Cancer
Interventions: BIOLOGICAL: mutation and signal pathway activation status analysis Drug: FORFIRINOX
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pulse Wave Analysis and Velocity in Patients With Chronic Renal Failure: a Cross-sectional Observational Study to Assess Association With Left Ventricular Hypertrophy, Uremic Toxins and Inflammation.
Status: COMPLETED
Conditions: Arterial Stiffness|CHRONIC RENAL FAILURE|Left Ventricular Hypertrophy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Herbal Periodontal Patch (THPP) for Gingival Inflammation in Diabetics
Status: SUSPENDED
Conditions: Gingival Inflammation in Diabetic Patients
Interventions: DRUG: Transmucosal Herbal Periodontal Patch (THPP)|DRUG: Placebo Patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Novel Way to Estimate Epidural Depth in Morbidly Obese Parturient
Status: COMPLETED
Conditions: Obesity
Interventions: DEVICE: Sonosite S-Nerve® US system (SonoSite, Bothell,WA)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Pilot Study of Acupuncture Treatment for Dysphagia
Status: COMPLETED
Conditions: Carcinomas, Squamous Cell|Dysphagia
Interventions: DEVICE: Acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: OGX-011 and Docetaxel in Treating Patients With Metastatic or Locally Recurrent Solid Tumors
Status: COMPLETED
Conditions: Bladder Cancer|Breast Cancer|Kidney Cancer|Lung Cancer|Ovarian Cancer|Prostate Cancer|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: custirsen sodium|DRUG: docetaxel|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effective Concentration of Lidocaine With Fentanyl in Lumbar Epidural Anesthesia for Transurethral Resection of Prostate(TURP) in Elderly Patients
Status: COMPLETED
Conditions: BPH( Benign Prostate Hyperplasia)|TURP(Transurethral Resection of Prostate)
Interventions: DRUG: epidural block with lidocaine and fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Enhancing Operational Performance in Healthy Rested Soldiers With Pharmacological Stimulants
Status: UNKNOWN
Conditions: Cognition
Interventions: DRUG: Modafinil 200mg|DRUG: mixed amphetamine salts|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: A Study of RBT-3 in Healthy Volunteers and Volunteers With Stage 3-4 Chronic Kidney Disease
Status: COMPLETED
Conditions: Kidney Failure, Acute
Interventions: DRUG: RBT-3
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Preliminary Efficacy of Occupational Therapy Integrating Horses on Self-regulation in Youth With Autism
Status: RECRUITING
Conditions: Autism Spectrum Disorder
Interventions: BEHAVIORAL: OTEE HORS|BEHAVIORAL: OT Clinic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Quadratus Lumborum Block for Congenital Hip Dislocation Surgery
Status: COMPLETED
Conditions: Congenital Hip Dislocation
Interventions: DRUG: Bupivacaine|OTHER: Standard pain
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing Patient Satisfaction & Stress Distribution on Mandibular Ridge by Three Posterior Occlusal Scheme in Complete Denture
Status: UNKNOWN
Conditions: Edentulous
Interventions: OTHER: buccalized occlusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nab-Paclitaxel With Gemcitabine for Relapsed Small Cell Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Small Cell Lung Cancer (SCLC)
Interventions: DRUG: Nab-paclitaxel|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Prospective Virtual Study of Patient Reported Behaviors and Health Outcomes in Individuals With COVID-19
Status: COMPLETED
Conditions: SARS-CoV-2 Acute Respiratory Disease
Interventions: OTHER: SARS-CoV-2 Positive|OTHER: SARS-CoV-2 Negative
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase III Study of BMS-188667 in Subjects With Active Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Double-blind Abatacept|DRUG: Double-blind Placebo|DRUG: Open-label Abatacept
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pentoxifylline Plus Carvedilol vs Carvedilol Monotherapy in Preventing New Decompensation in Stable Cirrhotic Patients With Prior Decompensation
Status: NOT_YET_RECRUITING
Conditions: Liver Cirrhosis
Interventions: DRUG: Carvedilol|DRUG: Pentoxifylline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Programmed Intermittent Epidural Bolus Versus Continuous Epidural Infusion on Postoperative Analgesia in Pediatric Patients
Status: UNKNOWN
Conditions: Correctional Osteotomy
Interventions: DEVICE: Programmed intermittent epidural bolus|DEVICE: Continuous epidural infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Spray vs EMLA Cream on Pain During Intra-articular Injection
Status: UNKNOWN
Conditions: Adhesive Capsulitis of the Shoulder
Interventions: DEVICE: Walter Ritter Ethyl Chloride Spray|OTHER: Placebo Spray|OTHER: Placebo Cream|DRUG: EMLA Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety and Tolerability of a Nasal Spray in Patients With Chronic Allergic or Nonallergic Rhinitis
Status: COMPLETED
Conditions: Chronic Allergic Rhinitis|Nonallergic Rhinitis
Interventions: DRUG: Astepro Nasal Spray (0.1% azelastine hydrochloride)|DRUG: Astelin Nasal Spray (0.1% azelastine hydrochloride)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Gait Training Using Virtual Reality and Real-Time Feedback on Physiological and Functional Gait Performance in Persons With a Traumatic Lower Extremity Amputation
Status: UNKNOWN
Conditions: Elevated Metabolic Cost
Interventions: OTHER: Gait Training
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigation and Modulation of the Mu-opioid Mechanisms in TMD (in Vivo)
Status: TERMINATED
Conditions: Temporomandibular Disorder
Interventions: DEVICE: HD-tDCS*|DEVICE: Sham HD-tDCS*
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: VEGF Concentrations After Intravitreal Bevacizumab vs Ranibizumab as a Treatment for Type 1 ROP
Status: COMPLETED
Conditions: Retinopathy of Prematurity Both Eyes|Retinal Disease|Premature Birth|Eye Diseases
Interventions: DRUG: Bevacizumab Injection|DRUG: Ranibizumab Ophthalmic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Bone Marrow Derived Mesenchymal Stem Cells in Improving Heart Function in Patients With Heart Failure Caused by Anthracyclines
Status: COMPLETED
Conditions: Cardiomyopathy|Heart Failure
Interventions: OTHER: Laboratory Biomarker Analysis|OTHER: Standard of Care|DRUG: Mesenchymal Stem Cell Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pregabalin for Post-craniotomy Pain Control
Status: UNKNOWN
Conditions: To Assess the Beneficial Preemptive and Preventive Effects of PGL on the Immediate and Late (1- and 3 Months) Postoperative Analgesia Requirements
Interventions: DRUG: Pregabalin|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Drug-Drug Interaction (DDI) Study of LY3437943 in Obese Participants
Status: COMPLETED
Conditions: Obesity
Interventions: DRUG: LY3437943|DRUG: Midazolam|DRUG: Warfarin|DRUG: Caffeine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of INCB099280 in Combination With Axitinib in Adults With Advanced Solid Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Solid Tumors
Interventions: DRUG: INCB099280|DRUG: axitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BG00012 and Delay of Disability Progression in Secondary Progressive Multiple Sclerosis
Status: TERMINATED
Conditions: Multiple Sclerosis, Secondary Progressive
Interventions: DRUG: dimethyl fumarate|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Efficacy and Safety of Yi-Gan San in Children and Adolescents With Tourette's Disorder
Status: COMPLETED
Conditions: Tourette Disorder|Tic Disorders
Interventions: DRUG: Yigansan|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II ABT-888 With Cyclophosphamide
Status: COMPLETED
Conditions: Ovarian Cancer|Primary Peritoneal Cancer|Serous Carcinoma Cancer|Triple-Negative Breast Cancer|Fallopian Tube Cancer
Interventions: DRUG: ABT-888|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reversal of Opioid-induced Respiratory Depression With Opioid Antagonists
Status: RECRUITING
Conditions: Opioid Induced Respiratory Depression|Chronic Opioid Use
Interventions: DRUG: Narcan 40 MG/ML Nasal Spray|DRUG: Naloxone Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transversus Thoracis Muscle Plane Block Plus Rectus Sheath Block in the Perioperative Pain Management of Cardiac Surgery
Status: UNKNOWN
Conditions: Coronary Artery Bypass Grafting or Heart Valve Surgery Via Median Sternotomy
Interventions: PROCEDURE: Bilateral transversus thoracis muscle plane and rectus sheath block with ropivacaine|PROCEDURE: Bilateral transversus thoracis muscle plane and rectus sheath puncture with saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SIELLO Pilot Study for Comparison of Steroid Versus Non-Steroid Pacing Leads
Status: COMPLETED
Conditions: Arrhythmias, Cardiac
Interventions: DEVICE: SIELLO JT/T|DEVICE: Pacemaker therapy|DEVICE: BPPU JT/T
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effectiveness of a Lifestyle Intervention for Increasing Physical Activity in Adults With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: BEHAVIORAL: Physically Ready for Invigorating Movement Every Day (PRIME)|BEHAVIORAL: Program for Activity, Leisure Skills, and Socialization (PALSS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of Neoadjuvant Conformal Radiotherapy Plus Sorafenib for Patients With Soft Tissue Sarcoma of the Extremity and Body Wall
Status: COMPLETED
Conditions: Soft Tissue Sarcoma
Interventions: DRUG: Sorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study on Obesity Intervention With Physical Exercise Among Students in Changping District, Beijing
Status: COMPLETED
Conditions: Pediatric Obesity
Interventions: BEHAVIORAL: Physical activity guidance|BEHAVIORAL: Health education
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Letermovir (Prevymis) for CMV in Kidney and Pancreas Transplant Recipients
Status: RECRUITING
Conditions: Cytomegalovirus Infections|Kidney Transplant Infection|Pancreas Transplant
Interventions: DRUG: Letermovir
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lenalidomide and High Dose Melphalan Followed by Autologous Stem Cell Transplant in Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Lenalidomide plus Melphalan during autologous stem cell transplantation|DRUG: Lenalidomide maintenance
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low-Level Laser in Treatment of Head and Neck Lymphedema: A Pilot Study
Status: COMPLETED
Conditions: Head and Neck Cancer|Lymphedema|Fibrosis
Interventions: DEVICE: Low-Level Laser
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: COmparison of Clarus and Optos Ultrawide Field Imaging Systems for Geographic Atrophy
Status: RECRUITING
Conditions: Macular Degeneration, Age Related|Geographic Atrophy
Interventions: DEVICE: Spectralis FAF imaging|DEVICE: Optos imaging|DEVICE: Zeiss Clarus 700 imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: AZD2281 and Cisplatin Plus Gemcitabine to Treat Solid Tumor Cancers
Status: COMPLETED
Conditions: Neoplasms
Interventions: DRUG: AZD 2281|DRUG: Cisplatin|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of TP-03 for the Treatment of Demodex Blepharitis
Status: COMPLETED
Conditions: Blepharitis
Interventions: DRUG: TP-03, 0.25%|DRUG: TP-03 Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluate Optimal Dosing and Long-term Safety of D-galactose in PGM1-CDG
Status: NOT_YET_RECRUITING
Conditions: PGM1-CDG - Phosphoglucomutase 1-Related Congenital Disorder of Glycosylation
Interventions: DRUG: AVTX-801
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fasting Study of Ondansetron Tablets 24 mg and Zofran® Tablets 24 mg
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Ondansetron Tablets 24 mg|DRUG: Zofran® Tablets 24 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study on Safety and Efficacy of an Oral Contraceptive in Long Cycles
Status: COMPLETED
Conditions: Contraception
Interventions: DRUG: Flexible (extended) treatment of EE20/DRSP (YAZ, BAY86-5300)|DRUG: Fixed extended treatment of EE20/DRSP (YAZ, BAY86-5300)|DRUG: Standard 24+4 treatment of EE20/DRSP (YAZ, BAY86-5300)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Single Tooth Implant-supported Fixed Prosthetic Rehabilitation Using PEEK.
Status: ENROLLING_BY_INVITATION
Conditions: Prosthesis Survival
Interventions: DEVICE: Prosthetic single-tooth prosthesis using PEEK
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Pain and Exercise Training With Telerehabilitation on Lumbar Facet Joint Arthrosis
Status: COMPLETED
Conditions: Facet Joint Arthrosis|Low Back Pain
Interventions: BEHAVIORAL: Pain Neuroscience education + Progressive therapeutic exercise training|BEHAVIORAL: Progressive therapeutic exercise training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Herombopag in Patients With Thrombocytopenia Before Hepatectomy
Status: RECRUITING
Conditions: Hepatopathy
Interventions: DRUG: Hetrombopag|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prosthetic Outcomes and Clinical Performance of Implant Supported Zirconia Crowns
Status: NOT_YET_RECRUITING
Conditions: Dental Restoration|Dental Implant
Interventions: OTHER: Graded Zirconia Crown|OTHER: Conventional Zirconia Crown
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Galcanezumab (LY2951742) in Participants With Episodic Migraine
Status: COMPLETED
Conditions: Episodic Migraine
Interventions: DRUG: Galcanezumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Consecutive Fecal Microbiota Transplantation on Non-Alcoholic Fatty Liver Disease (NAFLD)
Status: UNKNOWN
Conditions: NAFLD
Interventions: OTHER: Gut microbiome transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Acute Exercise and Ibuprofen on Symptoms, Immunity, and Neural Circuits in Bipolar Depression
Status: RECRUITING
Conditions: Bipolar Depression
Interventions: OTHER: Exercise Session|DRUG: Ibuprofen 800 mg|OTHER: Rest|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Optimization of Atopic Dermatitis Treatment That Requires Second-line Systemic Therapy Through Predictive Models
Status: RECRUITING
Conditions: Atopic Dermatitis
Interventions: DRUG: Second-line systemic treatment|OTHER: Folllow-up of second-line systemic treatment already started
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intramedullary Femoral Reaming, Human Study
Status: COMPLETED
Conditions: Pulmonary Complications|Organ Failure|Systemic Inflammatory Response Syndrome
Interventions: PROCEDURE: the effect of delayed intramedullary reaming|PROCEDURE: the reaming of the femoral canal is performed with two different reaming devices
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cumulative and Booster Effects of Multisession Prefrontal tDCS in Adolescents With ASD
Status: RECRUITING
Conditions: Transcranial Direct Current Stimulation|Autistic Spectrum Disorder|Electroencephalography|Booster Effects
Interventions: DEVICE: Active-tDCS|DEVICE: Sham-tDCS|BEHAVIORAL: Cognitive training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Autologous Followed by Non-myeloablative Allogeneic Transplantation for Non-Hodgkin's Lymphoma
Status: TERMINATED
Conditions: Lymphoma, Non-Hodgkin
Interventions: DRUG: Cyclophosphamide|DRUG: BCNU|DRUG: Etoposide|DRUG: Filgrastim|DRUG: Antithymocyte globulin|DRUG: Cyclosporine|DRUG: Mycophenolate mofetil|DRUG: Rituximab|PROCEDURE: Autologous hematopoietic stem cell transplantation (auto-HSCT)|PROCEDURE: Allogeneic hematopoietic stem cell transplantation (allo-HSCT)|PROCEDURE: Total lymphoid irradiation|DRUG: CD34+ Cells|DRUG: Solu-Medrol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Azacitidine，Venetoclax，and Flumatinib in Newly Diagnosed Ph-positive Acute Leukemia and CML-AP/BP Patients
Status: COMPLETED
Conditions: Philadelphia Chromosome|Acute Myeloid Leukemia|Acute Lymphoblastic Leukemia|Chronic Myeloid Leukemia|Mixed Phenotype Acute Leukemia
Interventions: DRUG: Azacitidine|DRUG: Venetoclax|DRUG: Flumatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multidimensional Approach for COPD and High Complexity
Status: RECRUITING
Conditions: Chronic Obstructive Pulmonary Disease|Heart Failure|Chronic Disease
Interventions: BEHAVIORAL: Physical activity program|OTHER: Global therapeutic remodeling
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose-optimization in Adolescents Aged 13-17 Diagnosed With Attention-deficit/Hyperactivity Disorder (ADHD) Using Extended-release Guanfacine HCl
Status: COMPLETED
Conditions: Attention-Deficit/Hyperactivity Disorder
Interventions: DRUG: Extended-release Guanfacine Hydrochloride|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Efficacy of Different Natural Ingredients in Improving Gut Health in Adults With Leaky Gut.
Status: COMPLETED
Conditions: Gut Health
Interventions: DIETARY_SUPPLEMENT: PA-GH-01|DIETARY_SUPPLEMENT: MK-GH-04|DIETARY_SUPPLEMENT: TSH-GH-03|DIETARY_SUPPLEMENT: PA-GH-02
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Belumosudil to Block Chronic Lung Allograft Dysfunction (CLAD) in High Risk Lung Transplant Recipients
Status: NOT_YET_RECRUITING
Conditions: Lung Transplant
Interventions: DRUG: Belumosudil|DRUG: Placebo for Belumosudil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Pharmacokinetic (PK) Study of Extended-Release Epidural Morphine in Upper Abdominal Surgery
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: DepoDur (extended-release epidural morphine)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Goals for Reaching Optimal Wellness: GROWell
Status: ACTIVE_NOT_RECRUITING
Conditions: Pregnancy Related|Gestational Weight Gain|Postpartum Weight Retention|Overweight and Obesity
Interventions: BEHAVIORAL: GROWell (Interactive Obesity Treatment Approach)|BEHAVIORAL: Attention Support Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Intra Peritoneal Chemo Hyperthermia (IPCH) : Cellular and Metabolic Consequences
Status: TERMINATED
Conditions: Peritoneal Carcinomatosis From Colorectal or Ovarian Origin
Interventions: PROCEDURE: Surgery with IPCH|PROCEDURE: Without surgery and without IPCH
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Cholinergic Mechanisms of Attention in Aging
Status: RECRUITING
Conditions: Subjective Cognitive Decline
Interventions: DRUG: Mecamylamine Challenge|OTHER: Placebo Comparator Challenge
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Two Syringe Spinal Anesthesia Technique for Cesarean Section: A Simple Way to Achieve More Satisfactory Block and Less Hypotension
Status: COMPLETED
Conditions: Cesarean Section
Interventions: DRUG: fentanyl|DRUG: fentanyl|DRUG: Hyperbaric bupivacaine|DRUG: hyperbaric bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: DBS and Levodopa for Treating Freezing of Gait in Parkinson's Disease
Status: RECRUITING
Conditions: Freezing of Gait|Parkinson Disease
Interventions: DEVICE: STIM ON plus|DRUG: MED ON plus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transradial Versus Transulnar Artery Approach for Coronary Interventions
Status: UNKNOWN
Conditions: Arterial Access in Percutaneous Coronary Angiography or Intervention
Interventions: PROCEDURE: Transulnar arterial access|PROCEDURE: Transradial arterial access
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Heated Breathing Circuit on Intraoperative Core Temperature and Systemic Inflammation After Brain Surgery: a Prospective Randomized Study
Status: UNKNOWN
Conditions: Patients Scheduled for Brain Surgery
Interventions: DEVICE: conventional circuit|DEVICE: conventional humidification circuit|DEVICE: new humidifaction heat circuit
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Dose Finding Study With CYT003-QbG10 in Patients With House Dust Mite Allergy
Status: COMPLETED
Conditions: Rhinoconjunctivitis|Allergies
Interventions: DRUG: CYT003-QbG10|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vaccine Therapy in Treating Patients Undergoing Surgery for Recurrent Glioblastoma Multiforme
Status: COMPLETED
Conditions: Recurrent Central Nervous System Neoplasm
Interventions: BIOLOGICAL: BTSC mRNA-loaded DCs
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ClearPetra™ Vacuum-assisted Ureteral Access Sheath vs Traditional Approach
Status: NOT_YET_RECRUITING
Conditions: Nephrolithiasis|Kidney Stone
Interventions: DEVICE: ClearPetra Ureteral access sheath
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Pembrolizumab (MK-3475) in Combination With Bacillus Calmette-Guerin (BCG) in High-Risk Non-Muscle Invasive Bladder Cancer (HR NMIBC) (MK-3475-676/KEYNOTE-676)
Status: RECRUITING
Conditions: High-risk Non-muscle Invasive Bladder Cancer
Interventions: BIOLOGICAL: Pembrolizumab|BIOLOGICAL: BCG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Single-center, Open Trials to Evaluate the Safety of Freeze-dried Group ACYW135 Meningococcal Conjugate Vaccine
Status: UNKNOWN
Conditions: Meningococcal Meningitis
Interventions: BIOLOGICAL: freeze-dried group ACYW135 MCV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Fulvestrant Versus Fulvestrant Plus Palbociclib in Operable Breast Cancer Responding to Fulvestrant
Status: COMPLETED
Conditions: Breast Neoplasm Female
Interventions: DRUG: Fulvestrant 500mg|DRUG: Palbociclib 125mg|DRUG: Goserelin 3.6 MG|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT