pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Cholesterol and Fatty Acid Synthesis in Islet and Liver Transplant Patients and Effect of Dietary Intervention
Status: COMPLETED
Conditions: Immunosuppression|Hyperlipidemias|Diabetes Mellitus, Type 1
Interventions: DIETARY_SUPPLEMENT: Dietary intervention - supplements
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Health Dashboard Intervention to Improve Engagement With CPAP Therapy in PAP-Naïve Patients: Project Neo
Status: COMPLETED
Conditions: Sleep Apnea, Obstructive
Interventions: OTHER: Neo App
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Effect of Leukocyte and Platelet-rich Fibrin With Antimicrobial Photodynamic Therapy in Aggressive Periodontitis
Status: RECRUITING
Conditions: L-PRF|Photodynamic Therapy|Aggressive Periodontitis
Interventions: PROCEDURE: L-PRF with antimicrobial photodynamic therapy|PROCEDURE: antimicrobial photodynamic therapy without L-PRF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Outcome Analysis of POEM and Endoluminal Therapies
Status: ENROLLING_BY_INVITATION
Conditions: Achalasia|Gastric Fistula|Weight Gain After Primary Weight Loss Surgery|Marginal Ulcer|Stenoses|Gastric Nec
Interventions: PROCEDURE: Endoscopic Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Active Reminders on Oral Hygiene in Orthodontics
Status: UNKNOWN
Conditions: Oral Hygiene
Interventions: BEHAVIORAL: Reminders once a week|BEHAVIORAL: Verbal oral hygiene instructions|BEHAVIORAL: Reminders three times a week|BEHAVIORAL: Daily reminders
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect Of Coffee And Tea Drink On Gis Functions Healing Quality After Surgery in Patients Surgery
Status: RECRUITING
Conditions: Gastrointestinal Functions
Interventions: OTHER: TURKISH COFFEE DRINK|OTHER: FENNEL TEA DRINK
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ezetimibe Plus Simvastatin Versus Simvastatin in Untreated Subjects With High Cholesterol (P03435)
Status: COMPLETED
Conditions: Hypercholesterolaemia|Atherosclerosis
Interventions: DRUG: Ezetimibe + Simvastatin|DRUG: Simvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase II Clinical Trial to Evaluate Safety and Efficacy of XmAb20717 in Advanced Rare Cancers
Status: SUSPENDED
Conditions: Microsatellite High Cancers|Peritoneal Mesothelioma|Extrapulmonary High Grade|Neuroendocrine Carcinomas|Cervical Carcinoma|Hodgkin's Lymphoma|Pleural Mesothelioma|Small Cell Lung Cancer
Interventions: DRUG: XmAb20717
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preventing Lack of Iodine During Pregnancy
Status: TERMINATED
Conditions: Pregnancy
Interventions: DRUG: potassium iodide|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Targeted Evaluation, Action, & Monitoring of Traumatic Brain Injury
Status: COMPLETED
Conditions: Traumatic Brain Injury (TBI)
Interventions: BEHAVIORAL: Cognitive/Neuropsychological Testing|OTHER: Vestibular/Ocular-Motor Testing|OTHER: Cervical (Neck) Evaluation|OTHER: Sleep Evaluation|OTHER: HDFT MRI|OTHER: MR Spectroscopy (MRS)|OTHER: MEG (Magnetoencephalography)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: FT538 in Combination With Monoclonal Antibodies in Advanced Solid Tumors
Status: TERMINATED
Conditions: Solid Tumor, Adult
Interventions: DRUG: FT538|DRUG: Cyclophosphamide|DRUG: Fludarabine|COMBINATION_PRODUCT: Monoclonal antibody - Dose Escalation|COMBINATION_PRODUCT: Monoclonal antibody - Dose Expansion
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy in Treating Children With Relapsed Acute Leukemia, Acute Myeloid Leukemia, or Blastic Phase Chronic Myelogenous Leukemia
Status: COMPLETED
Conditions: Leukemia
Interventions: DRUG: topotecan hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nitazoxanide Pharmacokinetic Parameters in Renal Impaired Subjects
Status: COMPLETED
Conditions: Renal Impairment|Renal Disease|Kidney Disease
Interventions: DRUG: Nitazoxanide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Paediatric Rapid Sepsis Trigger (PRST) Tool
Status: COMPLETED
Conditions: Sepsis|Infection
Interventions: DEVICE: Pediatric Rapid Sepsis Trigger (PRST) tool|OTHER: Emergency Triage and Treatment (ETAT) guidelines
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: To Assess the Pharmacokinetics and Safety and Tolerability of Efanesoctocog Alfa (BIVV001)in Adults With Type 2N and 3 Von Willebrand Disease (VWD)
Status: COMPLETED
Conditions: Von Willebrand's Disease (VWD)
Interventions: DRUG: efanesoctocog alfa (BIVV001)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Assessing Lung Dynamics and Respiratory Functions in Minimal Flow Anesthesia: A Prospective Study
Status: COMPLETED
Conditions: Medium Flow Anesthesia|Minimal Flow Anesthesia|Pulmonary Function Test|Compliance, Patient|Peak Inspiratuar Pressure
Interventions: OTHER: Medium flow anesthesia|OTHER: Minimal flow anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SCREENING
Clinical trial: Rivastigmine Bioequivalence Trial With Multiple Application of Transdermal Patches (9.5mg/24h)
Status: COMPLETED
Conditions: Bioequivalence
Interventions: DRUG: RID-TDS 9.5 mg/24 h|DRUG: Exelon® 9.5 mg/24 h
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study of Total Neoadjuvant Chemotherapy With FLOT VS Standard Perioperative FLOT in Patients With Gastric or GEJ Cancer
Status: RECRUITING
Conditions: Gastric Adenocarcinoma|Gastroesophageal Junction Adenocarcinoma
Interventions: DRUG: Fluorouracil|DRUG: Leucovorin|DRUG: Oxaliplatin|DRUG: Docetaxel|BIOLOGICAL: GSCF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lenalidomide in Relapsed or Refractory Primary-cutaneous Large B-cell Lymphoma Leg-type : Multicentre Prospective Phase II Single Arm Trial of the French Study Group of Cutaneous Lymphoma
Status: COMPLETED
Conditions: Refractory Primary-cutaneous Large B-cell Lymphoma (Leg-type)
Interventions: DRUG: Lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Amino Acid Composition Reduces Frequency of Common Cold. Results of a Controlled Completely Masked Trial
Status: COMPLETED
Conditions: to Improve the Effectiveness of a Amino Acid Dietary Supplement in Chronic Pharyngeal Infections vs Placebo
Interventions: DIETARY_SUPPLEMENT: amino acid composition|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Antipyretic Efficacy of Oral and Intravenous Paracetamol and Intramuscular Diclofenac in Patients Presenting With Fever.
Status: COMPLETED
Conditions: Fever|Reduction in Temperature
Interventions: DRUG: Oral paracetamol|DRUG: Intravenous paracetamol|DRUG: Intramuscular diclofenac
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Alleviating Effects Against Dry Eye by Oral Intake of Cordyceps Cicadae Mycelia
Status: COMPLETED
Conditions: Dry Eye|Supplement
Interventions: DIETARY_SUPPLEMENT: Cordyceps Cicadae Mycelia|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Memory Improvement With Docosahexaenoic Acid Study (MIDAS)
Status: COMPLETED
Conditions: Age-Related Cognitive Decline|Age-Related Memory Disorders
Interventions: DIETARY_SUPPLEMENT: DHA (nutritional supplement) or placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Bioequivalence of the 20% and 30% Etoricoxib Tablet Formulations (0663-070)
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: etoricoxib|DRUG: Comparator: etoricoxib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Perioperative Pregabalin in Reducing the Incidence of Chronic Neuropathic Pain and Postthoracotomy Syndrome.
Status: COMPLETED
Conditions: Neuropathic Pain
Interventions: DRUG: Pregabalin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Hemiarthroplasty Compared to Total Hip Arthroplasty for Displaced Femoral Neck Fractures in the Elderly-elderly
Status: UNKNOWN
Conditions: Femoral Neck Fractures
Interventions: DEVICE: Cemented total hip arthroplasty|DEVICE: Cemented hemiarthroplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the CleanSweep™ Closed Suction System on Length of Mechanical Ventilation and Ventilator-Associated Events
Status: COMPLETED
Conditions: Mechanical Ventilation Complication
Interventions: DEVICE: CleanSweep Closed Suction System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: DEB-TACE+RALOX-HAIC vs DEB-TACE for Large HCC
Status: RECRUITING
Conditions: Hepatocellular Carcinoma Non-resectable
Interventions: DRUG: DEB-TACE+HAIC|DRUG: DEB-TACE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Steroid and Different Sites of Botulinum Toxin Injection in the Treatment of Lateral Epicondylalgia
Status: UNKNOWN
Conditions: Tennis Elbow
Interventions: DRUG: Botox-Epic|DRUG: Botox-Tend|DRUG: triamcinolone acetonide (Steroid)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Valproic Acid With Chemoradiotherapy for Non-Small-Cell Lung Cancer
Status: UNKNOWN
Conditions: Locally Advanced Inoperable Non-small-lung Cancer
Interventions: DRUG: Valproic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Two Treatment Regimens of 0.5 mg Ranibizumab Intravitreal Injections Guided by Functional and/or Anatomical Criteria, in Patients With Neovascular Age-related Macular Degeneration
Status: COMPLETED
Conditions: Neovascular Age-related Macular Degeneration
Interventions: DRUG: Ranibizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial To Test Safety And Efficacy Of Vaccination For Incurable HPV 16-Related Oropharyngeal, Cervical And Anal Cancer
Status: COMPLETED
Conditions: Cancer of Head and Neck|Cancer of Cervix|Cancer of Anus
Interventions: DRUG: DPX-E7 vaccine|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Use of PROCRIT (Epoetin Alfa) for the Treatment of Anemia in People With Chronic Kidney Disease Who Live in Long-term Care Facilities.
Status: COMPLETED
Conditions: Renal Failure , Chronic|Anemia
Interventions: DRUG: Epoetin Alfa|OTHER: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: "A Prospective Study of the Efficacy of Intracameral Dexamethasone (Dexycu™) Compared to Standard of Care Treatment for Post-Cataract Surgical Pain and Anterior Chamber Inflammation"
Status: UNKNOWN
Conditions: Cataract
Interventions: DRUG: Dexycu|DRUG: Standard of Care post operative eye drops (steroid, antibiotic, NSAID)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Maintenance of Remission With Budesonide Orodispersible Tablets vs. Placebo in Eosinophilic Esophagitis
Status: COMPLETED
Conditions: Eosinophilic Esophagitis
Interventions: DRUG: Budesonide 0.5mg orodispersible tablet twice daily|DRUG: Budesonide 1mg orodispersible tablet twice daily|DRUG: Placebo orodispersible tablet twice daily
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Prospective Study Comparing the Success Rate of Injection of (DefluxR) Versus (VantrisR) for VUR in Children
Status: UNKNOWN
Conditions: Vesico-Ureteral Reflux
Interventions: DRUG: Deflux|DRUG: Vantris
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Repurposing Atovaquone for the Treatment of Platinum-Resistant Ovarian Cancer
Status: RECRUITING
Conditions: Ovarian High Grade Serous Adenocarcinoma|Platinum-Resistant Ovarian Carcinoma
Interventions: DRUG: Atovaquone|PROCEDURE: Biopsy|PROCEDURE: Computed Tomography|PROCEDURE: Paracentesis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neoantigen Vaccine in Esophagus Cancer Patients Following Neoadjuvant Therapy and Surgical Resection
Status: RECRUITING
Conditions: Resectable Esophageal Cancer
Interventions: BIOLOGICAL: iNeo-Vac-P01|BIOLOGICAL: GM-CSF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Predicting Response to Standardized Pediatric Colitis Therapy
Status: COMPLETED
Conditions: Ulcerative Colitis
Interventions: DRUG: Mesalazine|DRUG: IV Corticosteroid|DRUG: Oral Corticosteroids|OTHER: Additional Therapies|PROCEDURE: Colectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SGLT2 Inhibition in Addition to Lifestyle Intervention and Risk for Complications in Subtypes of Patients With Prediabetes
Status: RECRUITING
Conditions: Type2diabetes|PreDiabetes|Renal Failure
Interventions: DRUG: Dapagliflozin (Forxiga®)|DRUG: Placebo matching Dapaglifolzin|BEHAVIORAL: Lifestyle Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: First in Human Study of 68Ga/64Cu-FAPI-XT117 PET/CT in Patients With Malignant Solid Tumors
Status: COMPLETED
Conditions: Malignant Solid Tumors
Interventions: DRUG: 2-4 mCi 68Ga/64Cu-FAPI-XT117|DRUG: 4-6 mCi 68Ga/64Cu-FAPI-XT117|DRUG: 6-8 mCi 68Ga/64Cu-FAPI-XT117
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of Glucagon, Ghrelin and Growth Hormone as Counterregulatory Hormones
Status: UNKNOWN
Conditions: Healthy
Interventions: DRUG: Saline|DRUG: Glucagon|DRUG: Placebo|DRUG: Atenolol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Assessment of Tolerance of Mobilizing Peripheral Hematopoietic Stem Cells by Plerixafor in Sickle Cell Patients
Status: COMPLETED
Conditions: Major Sickle Cell Syndrome of Type SS or Sβ Thalassemia
Interventions: DRUG: Plerixafor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Topical Pimecrolimus in the Treatment of Pityriasis Alba
Status: UNKNOWN
Conditions: Pityriasis Alba
Interventions: DRUG: Elidel (pimecrolimus 1%)|DRUG: Cold Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Aminolevulinic Acid-photodynamic Therapy for Facial Actinic Keratosis Treatment and Prevention
Status: RECRUITING
Conditions: Actinic Keratoses
Interventions: DRUG: ALA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Analysis of naïve Patients With Age-related Macular Degeneration of the Neovascular Type and Treated With Aflibercept (Eylea®) in "Treat-and-extend" at CHU Brugmann
Status: COMPLETED
Conditions: Age-related Macular Degeneration
Interventions: OTHER: Data extraction from medical files
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Correlative Study for Predicting Response and Toxicity in Patients Receiving Chemotherapy for Breast Cancer
Status: TERMINATED
Conditions: Breast Cancer
Interventions: PROCEDURE: Biopsy|PROCEDURE: Serum Collection|PROCEDURE: Urine Collection|DRUG: Doxorubicin|DRUG: Cyclophosphamide|DRUG: Capecitabine|DRUG: Vinorelbine|DRUG: Gemcitabine
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety & Efficacy of Dual Therapy With Raltegravir/Lamivudine
Status: UNKNOWN
Conditions: AIDS
Interventions: DRUG: Raltegravir/3TC|DRUG: EFV/TDF/FTC|DRUG: ATV/r + TDF/FTC or DRV/r + TDF/FTC|DRUG: DTG+ABC/3TC DTG+TDF/FTC EVG/cobi/TDF/FTC RAL+TDF/FTC|DRUG: EFV plus ABC/3TC or RPV/TDF/FTC|DRUG: ATV/r plus ABC/3TC|DRUG: DRV/r + ABC/3TC or LPV/r + ABC/3TC or LPV/r + TDF/FTC|DRUG: RAL plus ABC/3TC|DRUG: Other ART regimens
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Interest of Pulse Wave Velocity Measurement as a Predictor of Severity of Aortic Stenosis
Status: WITHDRAWN
Conditions: Pulse Wave|Aortic Stenosis
Interventions: OTHER: Study the relationship between the arterial rigidity of large vessels and the presence and severity of degenerative aortic constriction|OTHER: Control group without heart disease
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Effects of Continuous Positive Airway Pressure (CPAP) on Sympathetic Activity in Different Sites of Activation
Status: UNKNOWN
Conditions: Radionuclide Imaging (MIBG Scintigraphy)|Exercise Test|Blood Pressure Monitoring, Ambulatory|Sympathetic Nerve Activity|Catecholamines
Interventions: DEVICE: CPAP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Study to Assess the Effects of EVP-6124 on the QT/QTc Interval in Healthy Subjects
Status: COMPLETED
Conditions: Healthy Subjects|Cardiac Repolarization
Interventions: DRUG: EVP-6124|DRUG: Placebo|DRUG: Moxifloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Neuroaxial Prophylaxis for CABG
Status: UNKNOWN
Conditions: Coronary Artery Occlusion
Interventions: PROCEDURE: CABG|DRUG: thoracic epidural analgesia|DRUG: analgesia of opioids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Topical Anesthesia With Pressure Nebulized 2% Lidocaine During Awake Intubation
Status: UNKNOWN
Conditions: Difficult Airway
Interventions: PROCEDURE: times of topical anesthesia for glottis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluate the PK, PD, and Safety of Arhalofenate in Combination With Febuxostat for Hyperuricemia in Patients With Gout
Status: COMPLETED
Conditions: Gout|Hyperuricemia
Interventions: DRUG: Arhalofenate|DRUG: Febuxostat|DRUG: Arhalofenate|DRUG: Febuxostat|DRUG: Colchicine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Egg Intervention During Pregnancy in Indonesia
Status: ACTIVE_NOT_RECRUITING
Conditions: Weight Gain|Anemia, Iron Deficiency|Birth Weight|Birth Length|Child Development|Zinc Deficiency|Folate Deficiency|B12 Deficiency Vitamin|Amino Acid Deficiency|Mineral Deficiency|Vitamin A Deficiency|Fatty Acid Deficiency|Parasite Infestation|E. Coli Infection|Salmonella Infections|Shigella Infection|Protozoan Infections
Interventions: DIETARY_SUPPLEMENT: Egg intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Water Exchange Plus Acetic Acid Staining on the Detection of Flat Polyps During Colonoscopy
Status: UNKNOWN
Conditions: Adenoma Colon
Interventions: OTHER: acetic acid staining|OTHER: Water exchange colonoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Patient-controlled Sedation Versus Target-controlled Infusion in Orthopaedic Surgery Under Central Neuraxial Block
Status: COMPLETED
Conditions: Patient-controlled Sedation
Interventions: OTHER: patient-controlled sedation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Efficacy of Inspiratory Muscle Training on Elite Swimmers
Status: UNKNOWN
Conditions: Reactive Airways Dysfunction Syndrome (Disorder)|Muscle Weakness|Dyspnea
Interventions: OTHER: Inspiratory Muscle Training|OTHER: Sham Inspiratory Muscle Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Defocus (DIMS) Spectacles Versus Ortho-K Lenses (OKL) for Slowing Myopia Progression in Danish Children Aged 6-12 Years.
Status: ACTIVE_NOT_RECRUITING
Conditions: Myopia
Interventions: DEVICE: Defocus Incorporated Multiple Segment (DIMS) Spectacles|DEVICE: Orthokerathology lenses (OKL)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rate of Complete Symptom Relief, Prevention of Symptom Relapse: Grades A and B Esophagitis of Esomeprazole Therapy
Status: COMPLETED
Conditions: Erosive Esophagitis
Interventions: DRUG: Esomeprazole 40 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Echinacea in Children
Status: WITHDRAWN
Conditions: Upper Respiratory Infections
Interventions: BIOLOGICAL: Echinacea purpurea 100 mg/ml in liquid formulation|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Olanzapine Given in Combination With Zonisamide SR to Prevent Weight Gain in Schizophrenic Subjects
Status: TERMINATED
Conditions: Schizophrenia|Schizoaffective Disorder|Schizophreniform Disorder
Interventions: DRUG: zonisamide SR plus olanzapine|DRUG: Placebo plus olanzapine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Pain, Discomfort and Acceptance During the Orthodontic Treatment of Class III Malocclusion
Status: COMPLETED
Conditions: Class III Malocclusion|Cross Bite|Orthodontic Appliance Complication
Interventions: DEVICE: Removable Mandibular Retractor|DEVICE: Bone-anchored intermaxillary traction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Biological Response to Brief Psychological Challenge
Status: COMPLETED
Conditions: Acute Inflammatory Response to Psychological Stress
Interventions: BEHAVIORAL: Socio-evaluative speech task|BEHAVIORAL: Control, Quiet Rest
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: AUGMENTIN 1gm In Skin And Soft Tissue Infection
Status: COMPLETED
Conditions: Skin Diseases, Infectious|Infection, Soft Tissue
Interventions: DRUG: amoxicillin/clavulanate potassium 1gm
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Ningmitai Capsule in Patients With Chronic Prostatitis/Chronic Pelvic Pain Syndrome
Status: COMPLETED
Conditions: Chronic Prostatitis
Interventions: DRUG: Ningmitai Capsule|DRUG: Tamsulosin Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacologic Treatment of Congenital Nephrogenic Diabetes Insipidus
Status: COMPLETED
Conditions: Nephrogenic Diabetes Insipidus
Interventions: DRUG: sildenafil|DRUG: calcitonin|DRUG: hydrochlorothiazide/amiloride|DRUG: indomethacin|DRUG: Placebo for sildenafil|DRUG: placebo for calcitonin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Therapy for Children With Neuroblastoma
Status: COMPLETED
Conditions: Neuroblastoma
Interventions: DRUG: Gefitinib, Irinotecan, Cycophosphamide, Doxorubicin, Etoposide, Cisplatin, Topotecan, Carboplatin, Melphalan, 13-cis retinoic acid|PROCEDURE: Radiation therapy, Surgery, Peripheral Stem cell transplant
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Minocycline on Delirium Incidence in Critically Ill Patients
Status: COMPLETED
Conditions: Delirium|Coma
Interventions: DRUG: Minocycline|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Safety and Efficacy of Afamelanotide in Patients With Xeroderma Pigmentosum C and V
Status: RECRUITING
Conditions: Xeroderma Pigmentosum
Interventions: DRUG: Afamelanotide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oxidative Stress Markers Evaluation Before and After Periodontal Treatment of Diabetics Type 2 Patients
Status: UNKNOWN
Conditions: Diabetes Mellitus Type 2
Interventions: PROCEDURE: non- surgical periodontal treatment|PROCEDURE: Prophylaxis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Pain Neuroscience Education and Physical Exercise Program in Chronic Back Pain
Status: UNKNOWN
Conditions: Chronic Pain|Musculoskeletal Pain|Back Pain
Interventions: OTHER: Health Education|OTHER: Physical exercise|OTHER: Usual care in Primary Care Physiotherapy Units
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Concentric or Eccentric Virtual Reality Training Program in Subacute-stroke Patients With Hemispatial Neglect
Status: UNKNOWN
Conditions: Stroke|Neglect
Interventions: DEVICE: afferent virtual reality program|DEVICE: efferent virtual reality program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Triphala Tooth Wipes in Reduction of Streptococcus Mutans Colonies
Status: NOT_YET_RECRUITING
Conditions: Plaque Control
Interventions: OTHER: Triphala Tooth Wipe|OTHER: Chlorhexidine Tooth Wipe
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Cryoablation of Venous Vascular Malformations
Status: COMPLETED
Conditions: Venous Vascular Malformation
Interventions: DEVICE: Percutaneous Image-guided Cryoablation (FPRPR3508 IceRod® PLUS Needles)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Signia Stapler Versus Vessel Sealer Extend Energy Device With SureForm Stapling in Robotic-Assisted Segmentectomy
Status: COMPLETED
Conditions: Lung Cancer|Thoracic Cancer|Lung Neoplasm
Interventions: DEVICE: Medtronic Signia Stapler|DRUG: Da Vinci Vessel Sealer Extend Energy Device with SureForm Stapling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Implanted Loop Recorders for Detection and Management of Arrhythmia With Bruton Tyrosine Kinase Inhibitors
Status: RECRUITING
Conditions: Atrial Fibrillation|Supraventricular Arrhythmia|Ventricular Arrhythmias and Cardiac Arrest|Chronic Lymphocytic Leukemia|Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma
Interventions: DEVICE: Medtronic LINQ-2 Insertable Cardiac Monitor (ILR)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Docetaxel and Irinotecan in Treating Patients With Advanced Cancer of the Esophagus or Stomach
Status: COMPLETED
Conditions: Esophageal Cancer|Gastric Cancer
Interventions: DRUG: docetaxel|DRUG: irinotecan hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Selinexor in Treating Patients With Intermediate- and High-Risk Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome After Transplant
Status: COMPLETED
Conditions: Acute Myeloid Leukemia|de Novo Myelodysplastic Syndrome|Myelodysplastic Syndrome|Secondary Acute Myeloid Leukemia|Secondary Myelodysplastic Syndrome
Interventions: OTHER: Laboratory Biomarker Analysis|DRUG: Selinexor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acute Neural and Immune Effects of Alcohol in People Living With HIV Infection
Status: RECRUITING
Conditions: HIV-1-infection|Alcohol Drinking
Interventions: OTHER: Alcohol, ethyl, moderate dose|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Intravenous and Perineural Dexamethasone for Ultrasound-Guided Axillary Blocks
Status: COMPLETED
Conditions: Brachial Plexus Block Duration
Interventions: OTHER: intravenous 8 mg dexamethasone and perineural 0.8 ml of saline solution|OTHER: intravenous 0,8 ml of saline solution and perineural 8 mg of dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Intravesical Photodynamic Therapy (PDT) in BCG Refractory High-Risk Non-muscle Invasive Bladder Cancer (NMIBC) Patients
Status: COMPLETED
Conditions: Non-Muscle Invasive Bladder Cancer (NMIBC) Refractory to BCG
Interventions: DRUG: TLD1433 infusion and photodynamic therapy (PDT) treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Omega-3 Fatty Acid Supplementation and Fractional Iron Absorption in Obese South African Women
Status: COMPLETED
Conditions: Obesity
Interventions: DIETARY_SUPPLEMENT: Omega-3 long chain polyunsaturated fatty acids (n-3 LCPUFA)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety and Tolerability of Intravitreal Administration of VG901 in Patients With Retinitis Pigmentosa Due to Mutations in the CNGA1 Gene
Status: RECRUITING
Conditions: Retinitis Pigmentosa
Interventions: DRUG: VG901
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Geriatric and Quality of Life Assessments in Older Patients With Non-metastatic or Metastatic Head and Neck or Lung Cancer Undergoing Surgery or Chemoradiation and Their Caregivers
Status: COMPLETED
Conditions: Caregiver|Head and Neck Carcinoma|Lung Carcinoma|Metastatic Head and Neck Carcinoma|Metastatic Lung Carcinoma|Stage 0 Lung Cancer AJCC v8|Stage I Lung Cancer AJCC v8|Stage IA1 Lung Cancer AJCC v8|Stage IA2 Lung Cancer AJCC v8|Stage IA3 Lung Cancer AJCC v8|Stage IB Lung Cancer AJCC v8|Stage II Lung Cancer AJCC v8|Stage IIA Lung Cancer AJCC v8|Stage IIB Lung Cancer AJCC v8|Stage III Lung Cancer AJCC v8|Stage IIIA Lung Cancer AJCC v8|Stage IIIB Lung Cancer AJCC v8|Stage IIIC Lung Cancer AJCC v8|Stage IV Lung Cancer AJCC v8|Stage IVA Lung Cancer AJCC v8|Stage IVB Lung Cancer AJCC v8
Interventions: OTHER: Comprehensive Geriatric Assessment|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical Study With Ibrutinib and Venetoclax for Patients With Relapsed/Refractory Chronic Lymphocytic Leukemia
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Lymphocytic Leukemia
Interventions: DRUG: Venetoclax|DRUG: Imbruvica Oral Product
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GI-4000 With Adoptive Transfer in Pancreatic Cancer
Status: WITHDRAWN
Conditions: Pancreatic Cancer
Interventions: OTHER: Screening|BIOLOGICAL: GI-4000 Vaccine|BIOLOGICAL: GI-4000 Vaccine + Activated T Cells|BIOLOGICAL: Surgical Evaluation after Vaccine #4
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Efficacy and Safety of Norgestimate-ethinyl Estradiol and Cyproterone Acetate-ethinyl Estradiol in the Treatment of Acne Vulgaris
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: Norgestimate-ethinyl estradiol; Cyproterone acetate-ethinyl estradiol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: The Coping With and Caring for Infants With Special Needs Intervention in Down Syndrome Infants
Status: RECRUITING
Conditions: Down Syndrome|Family|Physical Disability
Interventions: PROCEDURE: Coping With and Caring for Infants With Special Needs|PROCEDURE: Standard Physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing Efficacy of Different Drugs Combinations for Serratus Anterior Block for Thoracotomy
Status: RECRUITING
Conditions: Post Operative Pain, Acute
Interventions: DRUG: patients will receive intraoperative serratus block with bupivacaine|DRUG: serratus block with bupivacaine /magnesium|DRUG: serratus block with bupivacaine with nalbuphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of Duloxetine (LY248686) in Participants With Diabetic Peripheral Neuropathic Pain (DPNP)
Status: COMPLETED
Conditions: Diabetic Peripheral Neuropathic Pain
Interventions: DRUG: Duloxetine|DRUG: Pregabalin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Mixed Reality and Virtual Reality Technology With Mirror Therapy for Stroke Rehabilitation
Status: RECRUITING
Conditions: Stroke|Cerebrovascular Disorders|Central Nervous System Diseases
Interventions: BEHAVIORAL: Virtual Reality-based Mirror Therapy (VR+MT)|BEHAVIORAL: Mixed Reality-based Mirror Therapy (MR+MT)|BEHAVIORAL: Traditional Mirror Therapy (MT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Maternal Self-efficacy and Motor Development in Premature Infants: Clinical Trial Protocol
Status: NOT_YET_RECRUITING
Conditions: Premature Birth|Mothers of Newborn Infants
Interventions: BEHAVIORAL: Interdisciplinary intervention program on maternal self-efficacy and the motor development of premature children|BEHAVIORAL: Traditional kangaroo program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Post-Approval Study for the FLAIR Endovascular Stent Graft
Status: COMPLETED
Conditions: Stenosis of Vascular Prosthetic Devices, Implants and Grafts
Interventions: DEVICE: FLAIR Endovascular Stent Graft|PROCEDURE: PTA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Topical Tranexamic Acid in Reducing Blood Loss During CS in Patients With Placenta Previa
Status: NOT_YET_RECRUITING
Conditions: Placenta Previa
Interventions: DRUG: Topical tranexamic acid|DRUG: Intravenous tranexamic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Assessment of Thoughts and Feelings Occurring During and After a Meal
Status: WITHDRAWN
Conditions: Behavior and Behavior Mechanisms|Food Habits|Feeding Behavior|Behavior
Interventions: BEHAVIORAL: Food Feelings|BEHAVIORAL: Other Feelings
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Intellivent ASV in Chronic Obstructive Pulmonary Disease Patients in the ICU
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DEVICE: Intellivent ASV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Comprehensive Dietary Counseling on Dietary Quality, Mental Health, and Quality of Life in Older Adults
Status: UNKNOWN
Conditions: Aging|Age Problem|Age-related Cognitive Decline|Age-Related Atrophy
Interventions: BEHAVIORAL: Dietary Counselling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Clinical Trial to Compare and Evaluate the Safety and Pharmacokinetic After Oral Administration of CKD-341 and D958 in Healthy Adults
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: CKD-341, D958
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Supervised Versus Home Based Exercises Neck and Low Back Pain Among Students Due to Quarantine During COVID-19
Status: COMPLETED
Conditions: Musculoskeletal Pain
Interventions: OTHER: Supervised stretching and strengthening exercise|OTHER: Home-based stretching and strengthening exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of Subcutaneous Amlitelimab Monotherapy Compared With Placebo in Participants Aged 12 Years and Older With Moderate-to-severe Atopic Dermatitis (COAST 2)
Status: RECRUITING
Conditions: Dermatitis Atopic
Interventions: DRUG: Amlitelimab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Trans Fatty Acids From Natural and Industrial Origin in the Induction of Insulin Resistance Development
Status: COMPLETED
Conditions: Insulin Resistance|Obesity
Interventions: DIETARY_SUPPLEMENT: vaccenic acid enriched diet|DIETARY_SUPPLEMENT: Elaidic acid enriched diet|DIETARY_SUPPLEMENT: control diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Phase II Study for Previously Untreated Subjects With Non Small Cell Lung Cancer (NSCLC) or Small Cell Lung Cancer (SCLC)
Status: COMPLETED
Conditions: Lung Cancer|Small Cell Lung Cancer|Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: Ipilimumab|DRUG: Placebo|DRUG: Paclitaxel|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Using Effective Provider-Patient Communication to Improve Cancer Screening Among Low Literacy Patients
Status: COMPLETED
Conditions: Cervical Cancer|Breast Cancer|Colorectal Cancer
Interventions: OTHER: Cancer risk communication skills training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Sodium Bicarbonate to Prevent Acute Kidney Injury in Children Undergoing Cardiac Surgery
Status: TERMINATED
Conditions: Acute Kidney Injury|Congenital Heart Disease
Interventions: DRUG: Sodium Bicarbonate|DRUG: Sodium Chloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Optimal Adjuvant Intravesical Therapy for Intermediate Risk Non Muscle Invasive Bladder Cancer: A Randomized Controlled Trial
Status: UNKNOWN
Conditions: Bladder Cancer
Interventions: DRUG: Intravesical Bcg|DRUG: Intravesical chemotherapy (epirubicin)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A National Multicenter, Real-world Study of Linperlisib in the Treatment of Lymphoma
Status: NOT_YET_RECRUITING
Conditions: Indolent B-cell Lymphoma
Interventions: DRUG: Linperlisib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Conversion Therapy of Sintilimab in Combination With Fruquintinib and Chemotherapy Versus Sintilimab and Chemotherpay in Stage IV Gastric Cancer
Status: NOT_YET_RECRUITING
Conditions: Gastric Cancer|Gastric Adenocarcinoma|Gastroesophageal Junction Adenocarcinoma
Interventions: DRUG: Sintilimab + Fruquinitinib + S-1 plus nab-paclitaxel|DRUG: Sintilimab + S-1 plus nab-paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Deep Vein Thrombosis (DVT) Prevention in Total Hip Arthroplasty: Continuous Enhanced Circulation Therapy (CECT) Versus Low Molecular Weight Heparin (LMWH)
Status: COMPLETED
Conditions: Deep Vein Thrombosis of Lower Limb|Pulmonary Embolism (PE)|Bleeding
Interventions: DEVICE: ActiveCare CECT device|DRUG: Enoxaparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Research Study in Children With a Low Level of Hormone to Grow. Treatment is Somapacitan Once a Week Compared to Norditropin® Once a Day (REAL4)
Status: ACTIVE_NOT_RECRUITING
Conditions: Growth Hormone Deficiency in Children
Interventions: DRUG: Somapacitan|DRUG: Norditropin®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Efficacy and Safety of ACP-044 in Subjects With Pain Associated With Osteoarthritis of the Knee
Status: TERMINATED
Conditions: Osteoarthritis Pain
Interventions: DRUG: ACP-044 Dose A|DRUG: ACP-044 Dose B|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT