pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Feasibility Study Assessing The Ability Of An Insulin Pump-Controlling Algorithm To Minimize Hypoglycemia And Hyperglycemia In Patients With Type 1 Diabetes In A Clinical Research Setting
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus
Interventions: DEVICE: Hypoglycemia-Hyperglycemia Minimizer System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Study to Evaluate the Safety and the Pharmacokinetics of IY-NT-T
Status: NOT_YET_RECRUITING
Conditions: Pharmacokinetics
Interventions: DRUG: IY-NT-T|DRUG: IY-NT-R
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nonalcoholic Fatty Liver Disease (NAFLD) Pharmacological Treatment: Metformin Versus Atorvastatin
Status: UNKNOWN
Conditions: Nonalcoholic Fatty Liver Disease (NAFLD)
Interventions: DRUG: Low dose metformin|DRUG: Metformin|DRUG: Atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reduction of Low-Density Lipoprotein Cholesterol (LDL-C) With PCSK9 Inhibition in Heterozygous Familial Hypercholesterolemia Disorder Study
Status: COMPLETED
Conditions: Hypercholesterolemia, Familial
Interventions: BIOLOGICAL: Evolocumab|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Glycopyrronium in Combination With Tropisetron in Anti-postoperative Nausea and Vomiting
Status: COMPLETED
Conditions: Postoperative Nausea and Vomiting
Interventions: DRUG: Glycopyrronium in Combination With Tropisetron|DRUG: Normal Saline in Combination With Tropisetron
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Controlled Trial Examining the Efficacy of Botulinum Toxin in Biopsy Scar Minimization
Status: ACTIVE_NOT_RECRUITING
Conditions: Scar|Hypertrophic Scar
Interventions: DRUG: Botulinum Toxin|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Chemotherapy and Peripheral Stem Cell Transplant With or Without Monoclonal Antibody Therapy in Treating Patients With Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: BIOLOGICAL: filgrastim|BIOLOGICAL: rituximab|DRUG: carmustine|DRUG: cisplatin|DRUG: cytarabine|DRUG: dexamethasone|DRUG: etoposide|DRUG: ifosfamide|DRUG: melphalan|DRUG: methotrexate|PROCEDURE: bone marrow ablation with stem cell support|PROCEDURE: peripheral blood stem cell transplantation|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Internet and Telephone Support Intervention for Stroke Caregivers
Status: COMPLETED
Conditions: Depression|Quality of Life|Recovery of Function|Self Efficacy|Stress
Interventions: BEHAVIORAL: Caregiver problem-solving|BEHAVIORAL: Attention Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Olaparib+Trastuzumab in HER2[+],Breast Cancer Susceptibility Gene (BRCA) Mutated Advanced Breast Cancer
Status: TERMINATED
Conditions: Advanced Breast Cancer
Interventions: DRUG: Olaparib [Lynparza®] plus Trastuzumab [Herceptin®]
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GENERATION HD2. A Study to Evaluate the Safety, Biomarkers, and Efficacy of Tominersen Compared With Placebo in Participants With Prodromal and Early Manifest Huntington's Disease.
Status: RECRUITING
Conditions: Huntington Disease
Interventions: DRUG: Tominersen 60 mg|DRUG: Placebo|DRUG: Tominersen 100 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ELDOA Technique Versus Lumbar SNAGS With Motor Control Exercises
Status: COMPLETED
Conditions: Low Back Pain
Interventions: OTHER: ELDOA exercises|OTHER: Lumbar SNAGS and motor control exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Technology-Based Psychosocial Empowerment Program for Home Care of Children With Cancer and Their Parents
Status: NOT_YET_RECRUITING
Conditions: Cancer|Child, Only|Empowerment
Interventions: OTHER: Psychosocial program|OTHER: Standart care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Early Treatment of ARNI on Myocardial Remodeling and Progress
Status: UNKNOWN
Conditions: Myocardial Infarction
Interventions: DRUG: sacubitril/valsartan|DRUG: perindopril|OTHER: Cardiopulmonary Exercise Test|OTHER: Echocardiogram
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Gemcitabine, Carboplatin, and Bortezomib in Advanced or Recurrent Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Recurrent Non-small Cell Lung Cancer|Stage IIIB Non-small Cell Lung Cancer|Stage IV Non-small Cell Lung Cancer
Interventions: DRUG: gemcitabine hydrochloride|DRUG: carboplatin|DRUG: bortezomib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Short Term Efficacy of 5% Dextrose Injection With Ultrasound Guided Nerve Hydrodissection Method in CTS
Status: COMPLETED
Conditions: Carpal Tunnel Syndrome
Interventions: DEVICE: wrist splint|PROCEDURE: 5% dextrose injection using USG-guided nerve hydrodissection method
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Time Interval Between Ovulation Trigger With Triptorelin Acetate and Oocyte Retrieval
Status: COMPLETED
Conditions: Female Urogenital Diseases
Interventions: DRUG: Decapeptyl® diario|DRUG: Decapeptyl® daily
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Injectable Vitamin D Supplementation in Females With Polycystic Ovary Syndrome
Status: RECRUITING
Conditions: Anovulatory Infertility
Interventions: DRUG: Vitamin D|OTHER: Active Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: STRATOB: a Randomized Controlled Clinical Trial of Cognitive Behavioural Therapy and Brief Strategic Therapy With Telecare for Binge-eating Disorder
Status: COMPLETED
Conditions: Obesity|Binge Eating Disorder
Interventions: BEHAVIORAL: CBT vs BST
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Lignocaine Nebulization Versus Airway Block for Awake Nasal Fiberoptic Intubation in Patients With Head and Neck Burns.
Status: COMPLETED
Conditions: Practicality, Efficacy, and Ease of Lignocaine Nebulization Compared to Traditional Upper Airway Block for Awake Nasal Fiberoptic Intubation
Interventions: PROCEDURE: Awake nasal fiberoptic intubation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics of Suvorexant in Participants With Impaired Renal Function (MK-4305-023)(COMPLETED)
Status: COMPLETED
Conditions: Insomnia
Interventions: DRUG: Suvorexant
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vascular and Metabolic Effects of Vitamin D Supplementation Associated With Lifestyle Management in Obese Adolescents
Status: COMPLETED
Conditions: Obesity
Interventions: DRUG: Vitamin D supplementation|DRUG: Placebo|OTHER: 3 months lifestyle and dietary management|OTHER: Normal control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: ACT DiamondTemp TempeRAture-Controlled and Contact Sensing RF Ablation Clinical Trial for Atrial Fibrillation
Status: COMPLETED
Conditions: Paroxysmal Atrial Fibrillation
Interventions: DEVICE: Radio frequency (RF) Cardiac ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Can Adequacy of Anesthesia Depth and Quality of Recovery be Influenced by the Level of Neuromuscular Blockade?
Status: COMPLETED
Conditions: Neuromuscular Block
Interventions: DRUG: Sugammadex|DRUG: Rocuronium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Achillestendinopathy Treated With Proximal Medial Gastrocnemius Recession
Status: RECRUITING
Conditions: Achilles Tendinopathy|Chronic Pain
Interventions: PROCEDURE: Proximal Medial Gastrocnemius Recession
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Thalidomide Enhances Clinical Efficacy of Cetuximab Combined With Standard Chemotherapy for Left Colorectal Cancer
Status: NOT_YET_RECRUITING
Conditions: Thalidomide Enhances Clinical Efficacy of Cetuximab Combined With Standard Chemotherapy for Left Colorectal Cancer
Interventions: DRUG: Thalidomide+cetuximab+FOLFOX/FOLFIRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Motivating Campus Change Project Pilot Study
Status: COMPLETED
Conditions: Drinking Behavior
Interventions: BEHAVIORAL: Simultaneous Post Feedback Intervention Delivery|BEHAVIORAL: Sequential Post Feedback Intervention Delivery|BEHAVIORAL: Text Message Boosters
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of AK104, a PD-1/CTLA-4 Bispecific Antibody, for Advanced Solid Tumors or With mXELOX/XELOX as First-line Therapy for Advanced Gastric or GEJ Adenocarcinoma
Status: COMPLETED
Conditions: Gastric Adenocarcinoma|Advanced Solid Tumors|Gastroesophageal Junction Adenocarcinoma
Interventions: BIOLOGICAL: AK104|DRUG: Oxaliplatin|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Infigratinib in Children With Achondroplasia
Status: ACTIVE_NOT_RECRUITING
Conditions: Achondroplasia
Interventions: DRUG: Infigratinib 0.016 mg/kg|DRUG: Infigratinib 0.032 mg/kg|DRUG: Infigratinib 0.064 mg/kg|DRUG: Infigratinib 0.128 mg/kg|DRUG: Infigratinib 0.25 mg/kg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, and Immunogenicity of a Booster Dose of Zoster Vaccine, Live (V211-029)
Status: COMPLETED
Conditions: Herpes Zoster|Varicella-zoster Vaccine
Interventions: BIOLOGICAL: Zoster Vaccine, Live
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effectiveness of a Hospital Addiction Service in Treating Opioid and Alcohol Addiction
Status: UNKNOWN
Conditions: Alcohol Addiction|Opiate Addiction
Interventions: OTHER: Delayed Intervention (DI)|OTHER: Rapid Intervention (RI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cataract Surgery in Patients With Pseudoexfoliation and Pseudoexfoliation Glaucoma
Status: UNKNOWN
Conditions: Pseudoexfoliation|Pseudoexfoliation Syndrome|Pseudoexfoliation Glaucoma|Cataract
Interventions: PROCEDURE: Cataract surgery|PROCEDURE: Cataract surgery with extra anterior chamber angle aspiration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: New Method Using Deuterium Labelled Creatine to Measure Total Body Skeletal Muscle Mass
Status: COMPLETED
Conditions: Sports Nutritional Sciences
Interventions: DIETARY_SUPPLEMENT: D3 Creatine|DIETARY_SUPPLEMENT: Creatine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study to Evaluate the Immunogenicity and Safety of GlaxoSmithKline (GSK) Biologicals' Herpes Zoster Vaccine GSK1437173A When Co-administered With GSK Biologicals' Seasonal Influenza Vaccine GSK2321138A in Adults Aged 50 Years and Older
Status: COMPLETED
Conditions: Herpes Zoster
Interventions: BIOLOGICAL: Herpes Zoster vaccine GSK 1437173A|BIOLOGICAL: GSK Biologicals' quadrivalent seasonal influenza vaccine FLU-D-QIV GSK2321138A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Validity and Reliability of the Modified Delirium Diagnostic Tool - Provisional (DDT-Pro) (Thai Version) in Peri-operative Fragility Hip Fracture Patient
Status: COMPLETED
Conditions: Old Age|Hip Fractures|Delirium
Interventions: DIAGNOSTIC_TEST: Delirium Diagnostic Tool-Provisional ( DDT-Pro )
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Comparative Study of LY900014 to Insulin Lispro (Humalog) in Healthy Participants
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: LY900014|DRUG: Insulin Lispro
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: ARGONAUT: Stool and Blood Sample Bank for Cancer Patients
Status: RECRUITING
Conditions: Non-small Cell Lung Cancer|Colorectal Cancer|Triple Negative Breast Cancer|Pancreas Cancer
Interventions: DRUG: Immunotherapy|DRUG: Chemotherapy|PROCEDURE: CRC surgical resection|PROCEDURE: Colonoscopy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Efficacy of CELEXT07 in the Treatment of Toenail Onychomycosis
Status: UNKNOWN
Conditions: Onychomycosis
Interventions: DRUG: CELEXT07|DRUG: Penlac|OTHER: vehicle solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Combining Acupuncture and Acupressure for Dementia Elderly
Status: RECRUITING
Conditions: Dementia
Interventions: PROCEDURE: Comprehensive acupuncture therapy (CAT) (Hwato®/ Dongbang®)|PROCEDURE: Comfy Acupressure for the Elderly (CAE)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Imetelstat Sodium in Treating Participants With Primary or Secondary Myelofibrosis
Status: COMPLETED
Conditions: Primary Myelofibrosis|Secondary Myelofibrosis|Myeloid Malignancies
Interventions: DRUG: Imetelstat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pembrolizumab in Treating Patients With Advanced Uveal Melanoma
Status: TERMINATED
Conditions: Stage IIIA Uveal Melanoma|Stage IIIB Uveal Melanoma|Stage IIIC Uveal Melanoma|Stage IV Uveal Melanoma
Interventions: BIOLOGICAL: Pembrolizumab|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Treatment of Actinic Keratoses With Photodynamic Therapy Between MAL Cream and ALA Gel
Status: UNKNOWN
Conditions: Actinic Keratosis
Interventions: DRUG: METHYLAMINOLEVULINATE HYDROCHLORIDE|DRUG: AMINOLEVULINIC ACID HYDROCHLORIDE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Proof of Concept Study to Evaluate the Efficacy and Tolerability of Skinpen on Male and Female Subjects' Dorsal Hands as a Treatment of Hand Aging
Status: COMPLETED
Conditions: Skin Aging
Interventions: DEVICE: SkinPen Precision System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Developing Better Computerised Vision Tests (CVTV)
Status: RECRUITING
Conditions: Visual Impairment|Amblyopia|Macular Degeneration|Ophthalmic Disease
Interventions: DIAGNOSTIC_TEST: Near logMAR letter acuity|DIAGNOSTIC_TEST: Near LogMAR word acuity|DIAGNOSTIC_TEST: Red Green Stereoacuity|DIAGNOSTIC_TEST: Auckland Optotype/Auckland Vanishing Optotypes|DIAGNOSTIC_TEST: Vanishing Optotype Sloan Letters|DIAGNOSTIC_TEST: Letter Contrast Sensitivity|DIAGNOSTIC_TEST: Low Contrast Letter Acuity
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Randomized Comparison of Abciximab Plus Heparin With Bivalirudin in Acute Coronary Syndrome
Status: COMPLETED
Conditions: Myocardial Infarction|Coronary Disease
Interventions: DRUG: Abciximab + UFH|DRUG: Bivalirudin|DRUG: Heparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Gamified Electronic Medication Administration Record (eMAR) System
Status: COMPLETED
Conditions: Nurse's Role|Medication Administered in Error|Simulation of Physical Illness
Interventions: DEVICE: eMAR game|OTHER: Normal pre-work
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Assessment of Fatty Liver With Thermo-acoustic Device
Status: RECRUITING
Conditions: NASH|NAFLD|Non-alcoholic Fatty Liver|Non-Alcoholic Fatty Liver Disease|Non-alcoholic Steatohepatitis|Fatty Liver|Fatty Liver Disease
Interventions: DIAGNOSTIC_TEST: Thermo-acuostic image acquisition of liver|DIAGNOSTIC_TEST: MRI-PDFF estimation of hepatic fat
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Targeted Therapy With or Without Nephrectomy in Metastatic Renal Cell Carcinoma: Liquid Biopsy for Biomarkers Discovery
Status: TERMINATED
Conditions: Clear-cell Metastatic Renal Cell Carcinoma
Interventions: DRUG: sunitinib or pazopanib|PROCEDURE: Cytoreductive nephrectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Open-Label Study of the Safety, Tolerability, and Pharmacokinetics of Oral NNZ-2591 in Angelman Syndrome
Status: COMPLETED
Conditions: Angelman Syndrome
Interventions: DRUG: NNZ-2591
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating a One-Year Version of the Parent-Child Assistance Program
Status: NOT_YET_RECRUITING
Conditions: Alcohol Use Disorder|Substance Use Disorders|Pregnancy Related|Alcohol Use Complicating Pregnancy, Unspecified Trimester|Fetal Alcohol Syndrome|Fetal Alcohol Spectrum Disorders|Drug Use Disorders|Drug Use Complicating Pregnancy, Unspecified Trimester|Maternal Drugs Affecting Fetus|Maternal; Alcohol Use, Affecting Fetus
Interventions: BEHAVIORAL: Parent-Child Assistance Program - One-Year Version
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of Methods to Facilitate Rapid Sequence Intubation
Status: COMPLETED
Conditions: Intubating Condition
Interventions: DRUG: Magnesium Sulfate|DRUG: Ketamine|DRUG: rocuronium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: A Randomized Clinical Trail of The Effect of Postoperative Uric Acid Control on Stone Recurrence and Renal Function in Patients With Hyperuricemia of Urolithiasis.
Status: UNKNOWN
Conditions: Hypouricemia, Renal|Urolithiasis
Interventions: DRUG: Febuxostat 40mg Tab|BEHAVIORAL: Non-drug control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparison of Cilostazol-based Triple Antiplatelet Therapy Versus Dual Antiplatelet Therapy for Outcomes of below-the Knee Endovascular Intervention in Patients With Critical Limb Ischemia (TAP CLI Study)
Status: UNKNOWN
Conditions: Critical Limb Ischemia
Interventions: DRUG: Triple antiplatelet therapy (aspirin (100 mg), clopidogrel (75 mg), and cilostazol (200 mg) )|DRUG: Dual antiplatelet therapy (aspirin (100 mg) and clopidogrel (75 mg)) using aspirin and clopidogrel|DRUG: Dual antiplatelet therapy (aspirin (100 mg) and cilostazol (200 mg)) using aspirin and cilostazol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Recombinant Vaccinia Virus Prior to Sorafenib to Treat Unresectable Primary Hepatocellular Carcinoma
Status: COMPLETED
Conditions: Carcinoma, Hepatocellular
Interventions: DRUG: JX-594 followed by sorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low-Dose Fludarabine, Busulfan, and Anti-Thymocyte Globulin Followed By Donor Umbilical Cord Blood Transplant in Treating Patients With Advanced Hematologic Cancer
Status: COMPLETED
Conditions: Leukemia|Lymphoma|Multiple Myeloma and Plasma Cell Neoplasm|Myelodysplastic Syndromes
Interventions: BIOLOGICAL: anti-thymocyte globulin|BIOLOGICAL: sargramostim|DRUG: busulfan|DRUG: fludarabine phosphate|DRUG: mycophenolate mofetil|DRUG: tacrolimus|PROCEDURE: umbilical cord blood transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ferrous Acetyl-Aspartate Casein Formulation Evaluation Over Ferrous Sulfate in Iron Deficiency Anemia
Status: COMPLETED
Conditions: Iron Deficiency Anemia
Interventions: DRUG: Ferrous Sulfate|DRUG: Fe-ASP|DRUG: Ferrous Sulfate|DRUG: Fe-ASP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Surgery With or Without Radiation Therapy in Treating Patients With Primary Soft Tissue Sarcoma of the Retroperitoneum or Pelvis
Status: COMPLETED
Conditions: Sarcoma
Interventions: PROCEDURE: conventional surgery|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Atomoxetine for ATS and Opioid Dependence During Buprenorphine Maintenance Treatment in Malaysia
Status: COMPLETED
Conditions: Opiate Dependence|Stimulant Dependence
Interventions: DRUG: Atomoxetine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Role of GLP-1 Receptor Signalling in the Glucose-lowering Effect of Metformin in Patients With T2D
Status: COMPLETED
Conditions: Glucose Metabolism Disorders
Interventions: DRUG: Placebo Oral Tablet|DRUG: Metformin|DRUG: Saline|DRUG: Exendin (9-39)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Alerting Providers at Patient Hospital Discharge to Consider Prescribing Rivaroxaban to Reduce Venous Thromboembolism
Status: RECRUITING
Conditions: Venous Thromboembolic Disease|Pulmonary Embolism and Thrombosis|Deep Vein Thrombosis|Hospitalism
Interventions: OTHER: EHR (electronic health record) alert|OTHER: No EHR (electronic health record) alert
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Predicting the Clinical Response to Omalizumab With Anti-Immunoglobulin E (IgE) Ab Response or Syk Expression in Basophils
Status: COMPLETED
Conditions: Allergic Asthma
Interventions: DRUG: Omalizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single Photon Emission Computed Tomography (SPECT) Imaging Study to Develop a Biomarker for Alzheimer's Disease
Status: TERMINATED
Conditions: Alzheimer's Disease
Interventions: DRUG: I123MNI388/I123MNI390
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Exercise Intervention in Preventing Breast Cancer Recurrence in Postmenopausal Breast Cancer Survivors
Status: COMPLETED
Conditions: Cancer Survivor|Estrogen Receptor-positive Breast Cancer|Stage IA Breast Cancer|Stage IB Breast Cancer|Stage IIA Breast Cancer|Stage IIB Breast Cancer|Stage IIIA Breast Cancer|Postmenopausal
Interventions: BEHAVIORAL: exercise intervention|OTHER: laboratory biomarker analysis|OTHER: questionnaire administration|OTHER: quality-of-life assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Influence of Periodontal Disease Treatment on Serum Levels of Sirtuin 1 and Mannose-binding Lectin
Status: COMPLETED
Conditions: Periodontal Diseases
Interventions: PROCEDURE: treatment of periodontal disease
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of Topotecan/Vincristine With Subconjunctival Carboplatin for Patients With Bilateral Retinoblastoma
Status: WITHDRAWN
Conditions: Retinoblastoma
Interventions: DRUG: subtenon Carboplatin|DRUG: Topotecan Hydrochloride|DRUG: Vincristine|DRUG: Filgrastim
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Efficacy of Ticagrelor Combined With ASA to ASA Alone in Patients With Stroke
Status: COMPLETED
Conditions: Cerebrovascular Accident|Cerebrovascular Accident, Acute
Interventions: DRUG: ticagrelor + ASA|DRUG: Placebo+ASA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Assess the Possibility of Diagnosing Diabetes and Rediabetes Following Oral Induced Hyperglycemia in Patients With Dunnigan's Partial Familial Lipodystrophy by Replacing 75 g of Glucose With a Standardized Carbohydrate Breakfast and Continuous Interstitial Monitoring Glucose)
Status: RECRUITING
Conditions: Lipodystrophy
Interventions: DIAGNOSTIC_TEST: Standardized breakfast
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Chemotherapy Plus Bevacizumab and Anti-PD-1 Followed by Induction Therapy of Chemotherapy Plus Bevacizumab
Status: NOT_YET_RECRUITING
Conditions: Metastatic Colorectal Cancer|MSS
Interventions: DRUG: mFOLFOX6 regimen + bevacizumab + PD-1 monoclonal antibody
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of SPM 962 in Patients With Restless Legs Syndrome (RLS)
Status: COMPLETED
Conditions: Idiopathic Restless Legs Syndrome
Interventions: DRUG: SPM 962|DRUG: SPM 962|DRUG: Placebo of SPM 962
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Daily Magnesium-supplement for Severe Asthmatics
Status: COMPLETED
Conditions: Asthma
Interventions: DIETARY_SUPPLEMENT: Mablet (Magnesium-supplement)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective S&E Study of Wavefront-guided PRK for Myopia With iDesign Advanced Wavescan Studio™ System and Star S4 IR™
Status: COMPLETED
Conditions: Stable Myopic Refractive Error, With or Without Astigmatism
Interventions: DEVICE: STAR S4 IR laser with iDesign
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vascular Inflammation and Anti-inflammatory Supplements After Adverse Pregnancy Outcomes
Status: COMPLETED
Conditions: Pre-Eclampsia|Pre-Term|Intrauterine Growth Restriction|Hypertension in Pregnancy
Interventions: DIETARY_SUPPLEMENT: Anti-inflammatory supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Radium-223 Dichloride in Combination With Exemestane and Everolimus Versus Placebo in Combination With Exemestane and Everolimus in Subjects With Bone Predominant HER2 Negative Hormone Receptor Positive Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Neoplasms
Interventions: DRUG: Radium-223 dichloride (Xofigo, BAY88-8223)|DRUG: Placebo (saline)|DRUG: Exemestane|DRUG: Everolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: This Study Will Evaluate Efficacy and Safety of Deferasirox in Patients With Myelodysplastic Syndromes (MDS), Thalassemia and Rare Anemia Types Having Transfusion-induced Iron Overload.
Status: COMPLETED
Conditions: Myelodysplastic Syndrome|Thalassemia
Interventions: DRUG: Deferasirox
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Potential of Tazarotene Foam to Cause an Allergic Reaction When Applied to the Skin and Exposed to Light on Healthy Volunteers.
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: Tazarotene (Patch application in Challenge Phase)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Extended Retroperitoneal Lymphadenectomy and Nerve Plexus Clearance Versus Standard Lymphadenectomy in Pancreaticoduodenectomy
Status: UNKNOWN
Conditions: Pancreaticoduodenectomy
Interventions: PROCEDURE: extended lymphadenectomy and nerve clearance|PROCEDURE: standard lymphadenectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: SWITCH Clinical Trial for Patients With Rheumatoid Arthritis Who Have Failed an Initial TNF-blocking Drug.
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Etanercept|DRUG: Abatacept|BIOLOGICAL: Rituximab|DRUG: Adalimumab|DRUG: Certolizumab Pegol|DRUG: Infliximab|DRUG: Golimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Minayo Iron-rich Yeast Drink With SOD on Female Nutritional Anemia, Skin Condition and Qi-blood Deficiency Syndrome
Status: RECRUITING
Conditions: Anemia|Skin Condition
Interventions: DIETARY_SUPPLEMENT: Minayo Yeast Drink Product
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Tipranavir and Ritonavir on the Pharmacokinetic Characteristics of Methadone Administered in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Tipranavir|DRUG: Ritonavir|DRUG: Methadone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cyproheptadine in Severe COVID-19 : A Unblinded Randomized Trial
Status: UNKNOWN
Conditions: Viral Pneumonia|Serotonin Syndrome|Platelet Dysfunction
Interventions: DRUG: Cyproheptadine Hydrochloride 4 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Drug-drug Interaction Study of Ganaplacide and Lumefantrine With Itraconazole
Status: COMPLETED
Conditions: Malaria
Interventions: DRUG: Ganaplacide|COMBINATION_PRODUCT: Lumefantrine|DRUG: Itraconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ezetimibe/Simvastatin (MK-0653A) Versus Rosuvastatin Versus Doubling Statin Dose in Participants With Cardiovascular Disease and Diabetes Mellitus (MK-0653A-133)(COMPLETED)
Status: COMPLETED
Conditions: Cardiovascular Disorder|Diabetes Mellitus
Interventions: DRUG: ezetimibe (+) simvastatin|DRUG: simvastatin 40 mg or atorvastatin 20 mg|DRUG: Rosuvastatin|DRUG: atorvastatin 10 mg or simvastatin 20 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Vitamin K AntagonISt, Factor Xa Inhibitor Or Nothing In Atrial Fibrillation And DIalytic End-stage Renal DiseasE (VISIONAIRE)
Status: NOT_YET_RECRUITING
Conditions: Atrium; Fibrillation|Chronic Kidney Diseases
Interventions: DRUG: Anticoagulant Oral
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Psychological Well-being and Burnout in Healthcare Workers During the COVID-19 (Coronavirus Disease 2019) Pandemic
Status: ACTIVE_NOT_RECRUITING
Conditions: COVID-19|Burnout|Burnout, Professional|Work-related Illness|Work-Related Stress|SARS-CoV-2 Infection
Interventions: BEHAVIORAL: Positive Affect Regulation sKills (PARK)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Combined Treatment With CoQ10 and Methylphenidate in Children With Attention Deficit Hyperactivity Disorder
Status: UNKNOWN
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: DIETARY_SUPPLEMENT: Coenzyme Q10|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: High-Dose Gemcitabine, Busulfan and Melphalan With Hematopoietic-Cell Support for Patients With Poor-Risk Myeloma
Status: COMPLETED
Conditions: Myeloma
Interventions: DRUG: Palifermin|DRUG: Dexamethasone|DRUG: Gemcitabine|DRUG: Busulfan|DRUG: Melphalan|PROCEDURE: Stem Cell Transplant|DRUG: G-CSF
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Topical Proparacaine Eye Drops to Improve the Experience of Patients Undergoing Intravitreal Injections
Status: COMPLETED
Conditions: Age-related Macular Degeneration|Diabetic Macular Edema|Injection Site|Injection Site Infection|Pain, Postoperative
Interventions: DRUG: Proparacaine|PROCEDURE: Conjunctival culture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Anatomical sNuffbox for Coronary anGiography and IntervEntions
Status: COMPLETED
Conditions: Coronary Artery Disease|Vascular Access Complication
Interventions: PROCEDURE: Coronary angiography +/- percutaneous coronary intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Designing and Evaluating a School-based Hand Washing Program in Malawi
Status: UNKNOWN
Conditions: School-based, Hand-washing, Program, Malawi
Interventions: BEHAVIORAL: Hand Washing Program (HWP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study Evaluating A 13-Valent Pneumococcal Conjugate Vaccine Administered To Infants In Korea
Status: COMPLETED
Conditions: Pneumococcal Vaccine
Interventions: BIOLOGICAL: 13-valent pneumococcal conjugate vaccine|BIOLOGICAL: 7-valent pneumococcal conjugate vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Comparative Effects of Lower Body Quadrant Neural Mobilization and Stretching in Collegiate Football Players
Status: NOT_YET_RECRUITING
Conditions: Sports Physical Therapy|Stretch|Stretch Injury
Interventions: OTHER: Neural Mobilization Group (NMG)|OTHER: Dynamic Stretching Group (DSG)|OTHER: Static Stretching Group (SSG)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Ph I Ipilimumab Vemurafenib Combo in Patients With v-Raf Murine Sarcoma Viral Oncogene Homolog B1 (BRAF)
Status: TERMINATED
Conditions: Melanoma
Interventions: DRUG: Ipilimumab (BMS-734016)|DRUG: Vemurafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Retroclavicular Versus Costoclavicular Approach for Infraclavicular Brachial Plexus Block
Status: COMPLETED
Conditions: Disorder of Upper Extremity
Interventions: OTHER: retroclavicular approach|OTHER: costoclavicular approach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of Isometric and Isotonic Strengthening Exercises in Chronic Neck Pain Patients.
Status: COMPLETED
Conditions: Neck Pain
Interventions: OTHER: Isometric Exercises|OTHER: Isotonic Exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Is Theophylline More Effective Than Sumatriptan in the Treatment of Post-dural Puncture Headache
Status: COMPLETED
Conditions: Post-Dural Puncture Headache
Interventions: DRUG: Theophylline Anhydrous Oral Tablet|DRUG: Sumatriptan Succinate Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Controlled Study to Evaluate the Efficacy and the Tolerability of a Cosmetic Active Ingredient Intended for Subjects With Atopic Dermatitis
Status: COMPLETED
Conditions: Mild to Moderate Atopic Dermatitis
Interventions: OTHER: Isopentenyltheophylline 0.44% + Glycerin 4.56%|OTHER: Glycerin 4.56%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Does Dosage Matter: Ride-on Cars to Enhance Social-mobility Function and Motivation in Toddlers With Motor Disabilities
Status: COMPLETED
Conditions: Mobility Limitation
Interventions: BEHAVIORAL: A 48-hour ROC training program with a standing posture|BEHAVIORAL: A 24-hour ROC training program with a standing posture|BEHAVIORAL: A regular therapy program without receiving any ROC training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Double Randomized and Placebo Controlled Trail of Sanchitongshu Combined Antiplatelet Drug to Prevent Ischemic Stroke
Status: UNKNOWN
Conditions: Ischemic Stroke|Antiplatelet Effect
Interventions: DRUG: Sanchitongshu|DRUG: Aspirin|DRUG: Clopidogrel|DRUG: placebo of Sanchitongshu
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: the Effects of Different Exercise on Vascular Health
Status: NOT_YET_RECRUITING
Conditions: Mind-body Exercise|Vascular Health|M-health|Cardiac Rehabilitation
Interventions: BEHAVIORAL: Regular exercise|BEHAVIORAL: Baduanjin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Rate of Gastric Emptying in Term Parturients Undergoing Elective Cesarean Section
Status: UNKNOWN
Conditions: Gastric Emptying|Pregnancy
Interventions: DIETARY_SUPPLEMENT: Nutricia PreOp - a clear, non-carbonated, lemon flavoured, carbohydrate drink that provides 0.5kcal/ml
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimising Renal Outcome in Myeloma Renal Failure
Status: COMPLETED
Conditions: Multiple Myeloma|Chronic Kidney Disease
Interventions: DRUG: Bortezomib|DRUG: Thalidomide|DRUG: Bendamustine|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ONO-6950 in Healthy Adult Subjects
Status: COMPLETED
Conditions: Healthy Adult Subjects
Interventions: DRUG: ONO-6950|DRUG: ONO-6950
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Three Dimensional Navigation IntraCardiac Guidance Kit for Atrial Septal Puncture
Status: RECRUITING
Conditions: Atrial Fibrillation
Interventions: DEVICE: Three-Dimensional Navigation Atrial Septal Puncture|DEVICE: Conventional Atrial Septal Puncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Trabeculectomy Versus Peripheral Iridectomy Plus Goniotomy in Advanced PACG
Status: RECRUITING
Conditions: Primary Angle Closure Glaucoma
Interventions: PROCEDURE: Trabeculectomy|PROCEDURE: SPI+GSL+GT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Physiological Consequence of Silicone-hydrogel Care-solution Bio-incompatibility
Status: COMPLETED
Conditions: Contact Lens Solution Toxicity
Interventions: DEVICE: PureVision lenses soaked in ReNu Multiplus|DEVICE: PureVision lenses soaked in OptiFree RePlenish
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Neurofeedback and Working Memory Training for Children and Adolescents With ADHD
Status: COMPLETED
Conditions: Attention Deficit Disorder
Interventions: BEHAVIORAL: SCP training|BEHAVIORAL: Live Z-score training|BEHAVIORAL: WM training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Midazolam in Supraclavicular Brachial Plexus Block
Status: COMPLETED
Conditions: Forearm Surgeries
Interventions: DRUG: Bupivacaine|DRUG: Midazolam|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Low Dose Aspirin Inhibition of COX-2 Derived PGE2 in Male Smokers
Status: COMPLETED
Conditions: Tobacco Use Disorder|Smoking
Interventions: DRUG: Aspirin 325 mg daily|DRUG: Celecoxib 200 mg BID
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Low-Dose Naltrexone (LDN) for Depression Relapse and Recurrence
Status: COMPLETED
Conditions: Major Depressive Disorder|Depression, Unipolar|Recurrence|Relapse
Interventions: DRUG: Naltrexone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Investigational Study to Evaluate Experimental Medication BMS-986165 Compared to Placebo and a Currently Available Treatment in Participants With Moderate-to-Severe Plaque Psoriasis
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: BMS-986165|OTHER: Placebo|DRUG: Apremilast
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety of SBRT With Anti-PD1 and Anti-IL-8 for the Treatment of Multiple Metastases in Advanced Solid Tumors and Melanoma
Status: RECRUITING
Conditions: Melanoma|Unresectable Solid Tumors|Neoplasms|Neoplasms by Histologic Type|Neoplasms by Site|Antineoplastic Agents, Immunological|Antineoplastic Agents|Immune Checkpoint Inhibitors|Molecular Mechanisms of Pharmacological Action|Nivolumab
Interventions: DRUG: nivolumab|DRUG: BMS-986253|RADIATION: Stereotactic Body Radiotherapy (SBRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT