pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Comparing Group Therapies for Veterans With Depression and PTSD
Status: COMPLETED
Conditions: Major Depressive Disorder|Posttraumatic Stress Disorder
Interventions: BEHAVIORAL: Group Transdiagnostic Behavior Therapy|BEHAVIORAL: Group Disorder-Specific Therapy (G-DSTs)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multiphasic Neuroplasticity Based Training Protocol With Shock Wave Therapy For Post Stroke Spasticity
Status: UNKNOWN
Conditions: Stroke|Spasticity, Muscle
Interventions: OTHER: Shock wave therapy with multiphasic neuroplasticity based training protocol|OTHER: Conventional physical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An RCT in Treatment of Adhesive Capsulitis Arthrographic Joint Distention With Local Anesthetic Alone
Status: COMPLETED
Conditions: Adhesive Capsulitis
Interventions: DRUG: Triamcinalone (steroid) and lidocaine|OTHER: Lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Commitment Device for Medication Adherence Among HIV Patients
Status: COMPLETED
Conditions: Acquired Immunodeficiency Syndrome|HIV
Interventions: BEHAVIORAL: Provider Visit Incentive (PVI)|BEHAVIORAL: Incentive Choice (IC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Phase 1b/2a, Open-Label, Multi-Center Study of Tivozanib (AV-951) in Combination With Paclitaxel in Subjects With Advanced or Metastatic Breast Cancer
Status: COMPLETED
Conditions: Metastatic Breast Cancer
Interventions: DRUG: tivozanib (AV-951) + paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I Study of Belinostat in Combination With Cisplatin and Etoposide in Adults With Small Cell Lung Carcinoma and Other Advanced Cancers
Status: COMPLETED
Conditions: Carcinoma Neuroendocrine|Small Cell Lung Carcinoma|Malignant Epithelial Neoplasms
Interventions: DRUG: Belinostat|DRUG: Cisplatin|DRUG: Etoposide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing Alectinib With Crizotinib in Treatment-Naive Anaplastic Lymphoma Kinase-Positive Advanced Non-Small Cell Lung Cancer Participants
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: Alectinib|DRUG: Crizotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Esomeprazole for the Prevention of Preeclampsia
Status: UNKNOWN
Conditions: Pre-Eclampsia
Interventions: DRUG: Esomeprazole|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Topotecan, Vincristine, and Doxorubicin in Treating Young Patients With Refractory Stage 4 Neuroblastoma
Status: UNKNOWN
Conditions: Neuroblastoma
Interventions: BIOLOGICAL: filgrastim|DRUG: doxorubicin hydrochloride|DRUG: topotecan hydrochloride|DRUG: vincristine sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assess GSK Biologicals' MMR Vaccine (Priorix) When Given to Healthy Children at the Age of 12 to 18 Months in Singapore.
Status: COMPLETED
Conditions: Rubella|Mumps|Measles
Interventions: BIOLOGICAL: MMR vaccine (Priorix)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: PET/MR in the Staging and Efficacy Evaluation of Newly Diagnosed NK/T-cell Lymphoma
Status: RECRUITING
Conditions: NK/T-cell Lymphoma
Interventions: DEVICE: Positron Emission Tomography/Magnetic Resonance (PET/MR)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Safety Study of Bimatoprost in Patients With Glaucoma or Ocular Hypertension
Status: COMPLETED
Conditions: Glaucoma|Ocular Hypertension
Interventions: DRUG: Bimatoprost 0.01%|DRUG: Bimatoprost 0.03%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of D-Methadone in Patients With Chronic Pain
Status: COMPLETED
Conditions: Pain|Bladder Cancer|Breast Cancer|CNS Cancer|Colon Cancer|Esophageal Cancer|Pancreatic Cancer|Prostate Cancer|Uterine Cancer|Head and Neck Cancer|Eye Cancer|Otorhinolaryngologic Neoplasms
Interventions: DRUG: d-Methadone|DRUG: D-methadone|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Titrated Quantitative Conjunctival Provocation Test (tqCPT)
Status: COMPLETED
Conditions: Allergic Rhinitis
Interventions: OTHER: (diagnostic) conjunctival provocation test with solution: ALK 100, 1.000, 10.000, 20.000, 50.000 and 100.000 SQ-U/ml
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Doses of Coffee and Blood Pressure Response Post-exercise
Status: COMPLETED
Conditions: Post-Exercise Hypotension|Hypertension
Interventions: OTHER: CAF-1|OTHER: CAF-2|OTHER: CAF-3|OTHER: DESC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Combination of Insulin Sensitizer and Leptin as Treatment for the HAART -Induced Metabolic Syndrome
Status: COMPLETED
Conditions: HIV Lipodystrophy
Interventions: DRUG: Leptin|DRUG: Pioglitazone or metformin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Zero-fluoroscopic Navigation Versus Conventional Fluoroscopic Navigation for Single-chamber Pacemaker Implantation
Status: UNKNOWN
Conditions: Sick Sinus Syndrome|Complete Atrioventricular Block|High Degree Second Degree Atrioventricular Block|Bradycardia
Interventions: PROCEDURE: zero-fluoroscopy 3D navigation|PROCEDURE: conventional x-ray navigation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Computed Tomography (CT) Guided Lung Biopsy With Plug
Status: UNKNOWN
Conditions: Computed Tomography, Biopsy, Pneumothorax, Chest Tube, Plug
Interventions: DEVICE: The BioSentry Tract Sealant System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Helicobacter - Lymphoma - Radiation Part I: Eradication, Part II: Radiation
Status: UNKNOWN
Conditions: Lymphoma|Lymphoma, Non-Hodgkin
Interventions: DRUG: proton pump inhibitor|DRUG: clarithromycin|DRUG: amoxicillin|DRUG: metronidazole|PROCEDURE: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Molecular Analyses to Identify Pathways of Endocrine Resistance Following Short Term Neoadjuvant Endocrine Treatment in Patients With Hormone Receptor-Positive HER2-negative Breast Cancer
Status: NOT_YET_RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Aromatase inhibitors or tamoxifen
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Relative Bioavailability Study of SSP-004184AQ (Magnesium Salt) and SSP-004184SS (Disodium Salt)
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: SSP-004184AQ|DRUG: SSP-004184SS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Integrated Infectious Disease Capacity-Building Evaluation
Status: COMPLETED
Conditions: Capacity Building|Support for Midlevel Health Professionals|Diagnostic Training
Interventions: BEHAVIORAL: Training and supervision|BEHAVIORAL: Training and Supervision|BEHAVIORAL: Integrated Management of Infectious Disease (IMID)|BEHAVIORAL: Integrated Management of Infectious Disease (IMID)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Phase 1, Open-label Study of the Absorption, Metabolism, Excretion of [14C]-Resminostat
Status: COMPLETED
Conditions: Cutaneous T Cell Lymphoma|Mycosis Fungoides|Sezary Syndrome
Interventions: DRUG: [14C]-resminostat
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Dietary Strawberry Supplementation on Older Adults
Status: COMPLETED
Conditions: Aging|Age-related Memory Disorders
Interventions: DIETARY_SUPPLEMENT: Freeze-dried Strawberry|DIETARY_SUPPLEMENT: Strawberry Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Dialectical Behavioral Therapy Digital Health Solution for Outpatients Seeking Support for Substance Use
Status: COMPLETED
Conditions: Alcohol Use Disorder|Substance Use Disorders
Interventions: BEHAVIORAL: Dialectical behavioral therapy skills training (DBT-ST)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Maternal Interpretation Biases on Child Anxiety and Related Responses
Status: COMPLETED
Conditions: Anxiety Disorders
Interventions: OTHER: Positive Interpretation Bias Training|OTHER: Neutral Interpretation Bias Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Role of Early Systematic Best Palliative Care Versus on Request Palliative Care Consultation During Standard Oncologic Treatment for Patients With Advanced Gastric or Pancreatic Cancers: a Randomized, Controlled, Multicenter Trial.
Status: COMPLETED
Conditions: Pancreatic Neoplasm|Gastric Neoplasm
Interventions: OTHER: Interventional arm: Early best palliative care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Bioequivalence Study of Simvastatin 40 mg Film-coated Tablets in Healthy Thai Volunteers
Status: NOT_YET_RECRUITING
Conditions: Healthy Volunteer
Interventions: DRUG: Simvastatin 40 mg film-coated tablet|DRUG: Zocor 40 mg film-coated tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effect of Mother DHA Supplementation on Premature Newborn.
Status: COMPLETED
Conditions: Oxidative Stress
Interventions: DIETARY_SUPPLEMENT: DHA|DIETARY_SUPPLEMENT: control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Small Monetary Incentives to Promote Exercise (Exercise4Good; EX4G)
Status: COMPLETED
Conditions: Obesity|Physical Activity
Interventions: BEHAVIORAL: Incentives (Rebate)|BEHAVIORAL: Incentives (Donation)|BEHAVIORAL: Feedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Plinabulin in Combination With Radiation/Immunotherapy in Patients With Select Advanced Cancers After Progression on PD-1 or PD-L1 Targeted Antibodies
Status: RECRUITING
Conditions: Advanced Bladder Carcinoma|Advanced Lung Non-Small Cell Carcinoma|Advanced Malignant Solid Neoplasm|Advanced Melanoma|Advanced Merkel Cell Carcinoma|Advanced Renal Cell Carcinoma|Clinical Stage III Cutaneous Melanoma AJCC v8|Clinical Stage III Merkel Cell Carcinoma AJCC v8|Clinical Stage IV Cutaneous Melanoma AJCC v8|Clinical Stage IV Merkel Cell Carcinoma AJCC v8|Pathologic Stage III Cutaneous Melanoma AJCC v8|Pathologic Stage III Merkel Cell Carcinoma AJCC v8|Pathologic Stage IIIA Cutaneous Melanoma AJCC v8|Pathologic Stage IIIA Merkel Cell Carcinoma AJCC v8|Pathologic Stage IIIB Cutaneous Melanoma AJCC v8|Pathologic Stage IIIB Merkel Cell Carcinoma AJCC v8|Pathologic Stage IIIC Cutaneous Melanoma AJCC v8|Pathologic Stage IIID Cutaneous Melanoma AJCC v8|Pathologic Stage IV Cutaneous Melanoma AJCC v8|Pathologic Stage IV Merkel Cell Carcinoma AJCC v8|Stage III Bladder Cancer AJCC v8|Stage III Lung Cancer AJCC v8|Stage III Renal Cell Cancer AJCC v8|Stage IIIA Bladder Cancer AJCC v8|Stage IIIA Lung Cancer AJCC v8|Stage IIIB Bladder Cancer AJCC v8|Stage IIIB Lung Cancer AJCC v8|Stage IIIC Lung Cancer AJCC v8|Stage IV Bladder Cancer AJCC v8|Stage IV Lung Cancer AJCC v8|Stage IV Renal Cell Cancer AJCC v8|Stage IVA Bladder Cancer AJCC v8|Stage IVA Lung Cancer AJCC v8|Stage IVB Bladder Cancer AJCC v8|Stage IVB Lung Cancer AJCC v8
Interventions: BIOLOGICAL: Atezolizumab|DRUG: Avelumab|BIOLOGICAL: Durvalumab|BIOLOGICAL: Nivolumab|BIOLOGICAL: Pembrolizumab|DRUG: Plinabulin|RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: mHealth to Improve the Experience, Adherence to Drug Treatment and Positive Mental Health
Status: RECRUITING
Conditions: Fracture of Femur
Interventions: OTHER: Pharmacological education|OTHER: Training in the use of MyPlan Aplication|OTHER: Patient Experience
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Concomitant Infection of Intestinal Parasites and Helicobacter Pylori
Status: UNKNOWN
Conditions: Dyspepsia Abdominal Burning Pain Diarrhea Dysentery
Interventions: DIAGNOSTIC_TEST: H.pylori stool antigen rapid test and stool parasitological examination
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of a Physiotherapy Protocol for Gait and Functional Recovery After Stroke
Status: COMPLETED
Conditions: Stroke
Interventions: OTHER: Conventional physiotherapy|OTHER: Techniques based on patients' functional level were added.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect IV Ibuprofen and Inflammatory Responses
Status: COMPLETED
Conditions: Gallbladder Disease
Interventions: DRUG: ibuprofen|OTHER: sugar water/placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Antibacterial-coated Sutures at Time of Cesarean
Status: RECRUITING
Conditions: Surgical Site Infection|Surgical Wound Infection|Cesarean Section; Infection|Cesarean Section Complications
Interventions: DRUG: Vicryl-plus, monocryl-plus, PDS-plus (Triclosan-coated Sutures)|OTHER: Vicryl, monocryl, PDS (not coated with triclosan)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Sinus Disease in Young Children With Cystic Fibrosis
Status: RECRUITING
Conditions: Cystic Fibrosis in Children|Cystic Fibrosis|Chronic Rhinosinusitis (Diagnosis)|Olfactory Disorder|Olfactory Impairment
Interventions: DRUG: Ivacaftor or elexacaftor/tezacaftor/ivacaftor
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Neurobiological and Cognitive Changes Following Exposure to Either Sevoflurane- or Propofol-based Anesthesia in Children
Status: COMPLETED
Conditions: Cognitive Change|Behavior
Interventions: DRUG: Propofol|DRUG: Sevoflurane|DRUG: Ametop|DRUG: Ondansetron
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Marijuana Effects on Simulated Driving Performance
Status: COMPLETED
Conditions: Cannabis|Cannabis Use|Marijuana|Marijuana Usage|Alcohol Drinking
Interventions: DRUG: Marijuana|DRUG: Alcohol|DRUG: placebo alcohol|DRUG: Inactive marijuana
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Bioequivalence Between Two New Oral Nicotine Replacement Therapy Products and Nicorette® Microtab
Status: COMPLETED
Conditions: Tobacco Dependence
Interventions: DRUG: Code STD|DRUG: Code STE|DRUG: Nicorette Microtab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Urinary Stress Incontinence and Urgency in Women With EMSELLA
Status: RECRUITING
Conditions: Stress Urinary Incontinence|Urge Incontinence
Interventions: DEVICE: BTL EMSELLA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: De-Intensification of Postoperative Radiotherapy in Patients With Squamous Cell Carcinoma of the Head and Neck
Status: RECRUITING
Conditions: Squamous Cell Carcinoma of the Oral Cavity|Squamous Cell Carcinoma of the Larynx|Squamous Cell Carcinoma of the Hypopharynx|Squamous Cell Carcinoma of the Oropharynx
Interventions: RADIATION: Eliminating RT to the elective neck|RADIATION: RT standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BSE on Blood Glucose
Status: COMPLETED
Conditions: Blood Glucose, High
Interventions: DIETARY_SUPPLEMENT: BSE|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing BGB-3111 and Ibrutinib in Participants With Waldenström's Macroglobulinemia (WM)
Status: COMPLETED
Conditions: Waldenström's Macroglobulinemia
Interventions: DRUG: BGB-3111|DRUG: Ibrutinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Intermediate Expanded Use Trial of DFMO
Status: AVAILABLE
Conditions: Neuroblastoma|Medulloblastoma|Typical Teratoid Rhabdoid Tumor|Embryonal Tumor With Abundant Neuropil and True Rosettes|Ependymoblastoma|Medulloepithelioma
Interventions: DRUG: eflornithine HCl
Study Type: EXPANDED_ACCESS
Clinical trial: Brain-oscillation Synchronised Stimulation of the Prefrontal Cortex
Status: COMPLETED
Conditions: Depression
Interventions: DEVICE: Intermittent theta-burst stimulation|DEVICE: Negative-peak-triggered-TMS|DEVICE: Open-loop replay TMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Brief Alcohol Intervention to Reduce At-Risk Drinking Among Type 2 Diabetics
Status: COMPLETED
Conditions: At-risk Drinking|Type 2 Diabetes
Interventions: BEHAVIORAL: Brief alcohol intervention|BEHAVIORAL: General health education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Use of Erythritol Powder and Metronidazole Gel for the Non-surgical Treatment of Periodontitis
Status: COMPLETED
Conditions: Periodontal Pocket
Interventions: DRUG: metronidazole gel|PROCEDURE: ultrasonics|PROCEDURE: erythritol|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Iberdomide-dexamethasone Alone or in Combination With Standard MM Treatment Regimens in Transplant Ineligible Newly Diagnosed Patients.
Status: NOT_YET_RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: Iberdomide|DRUG: Dexamethasone|DRUG: Daratumumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of REGN 2810 Compared to Platinum-Based Chemotherapies in Participants With Metastatic Non-Small Cell Lung Cancer (NSCLC)
Status: ACTIVE_NOT_RECRUITING
Conditions: Carcinoma，Non-Small-Cell Lung|Lung Carcinomas, Non-Small-Cell|Non-small-cell Lung Carcinoma|Nonsmall Cell Lung Cancer
Interventions: DRUG: Pemetrexed|DRUG: Paclitaxel|DRUG: Gemcitabine|DRUG: Cisplatin|DRUG: Carboplatin|DRUG: cemiplimab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Development of an mHealth Behavioral Sleep Medicine Intervention for Use During Medication Assisted Treatment for MOUD
Status: NOT_YET_RECRUITING
Conditions: Opioid Use Disorder|Poor Quality Sleep
Interventions: DEVICE: mHealth application and sleep health education|DEVICE: Simplified mHealth application and sleep health education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of GPO Seasonal Trivalent Inactivated Influenza Vaccine in Healthy Thai Adults
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: an inactivated influenza vaccine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Inorganic Nitrate: Sex Differences in Muscle Contractile Function and Efficiency
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: concentrated beet root juice|DRUG: Placebo beet root juice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Sildenafil Treatment for Mild TBI
Status: TERMINATED
Conditions: Vascular System Injuries|Concussion, Brain|Post-Concussion Syndrome
Interventions: DRUG: Sildenafil Citrate|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Tramadol Combined With Local Anesthesia on Pain After the Surgical Extraction of Third Molars
Status: COMPLETED
Conditions: Pain After the Surgical Extraction of Third Molars
Interventions: DRUG: Local anesthetic + tramadol hydrochloride|DRUG: Only local anesthetic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Radial and Ulnar Artery Intervention in Patients With ST Elevated Myocardial Infarction
Status: COMPLETED
Conditions: ST Elevated Myocardial Infarction
Interventions: PROCEDURE: primary percutaneous coronary intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of at Home Pain Management Products on Acute Low Back Pain, Disability, and Range of Motion
Status: TERMINATED
Conditions: Low Back Pain|Acute Pain
Interventions: DEVICE: TheraBand Kinesiology Tape|DEVICE: Biofreeze|BEHAVIORAL: Advice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Eculizumab to Cemdisiran Switch in aHUS
Status: WITHDRAWN
Conditions: Atypical Hemolytic Uremic Syndrome
Interventions: DRUG: cemdisiran|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tolerability, Safety, and Efficacy Study of INGAP Peptide to Treat Type 1 Diabetes Mellitus in Adults
Status: TERMINATED
Conditions: Type 1 Diabetes Mellitus
Interventions: DRUG: INGAP Peptide|DRUG: INGAP Peptide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Kinematics for Subjects Implanted With a PFC Sigma Rotating Platform or Fixed Bearing TC3 Prosthesis
Status: COMPLETED
Conditions: Knee Prosthesis|Knee Arthroplasty
Interventions: DEVICE: DePuy fixed-bearing Total Condylar III (TC3) TKA|DEVICE: DePuy PFC Rotating Platform TC3 TKA
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: (TAA)-Specific Cytotoxic T-Lymphocytes to Pediatric Patients With Lymphomas (pediTACTAL).
Status: RECRUITING
Conditions: Hodgkins Lymphoma|Non Hodgkins Lymphoma
Interventions: BIOLOGICAL: TAA-specific CTLs
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efprezimod Alfa (CD24Fc, MK-7110) as a Non-antiviral Immunomodulator in COVID-19 Treatment (MK-7110-007)
Status: COMPLETED
Conditions: Coronavirus Disease 2019 (COVID-19)
Interventions: DRUG: Efprezimod alfa|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficiency Study of Triple-Site Cardiac Resynchronization in Patients With Heart Failure
Status: COMPLETED
Conditions: Congestive Heart Failure|Heart Disease
Interventions: DEVICE: Cardiac resynchronization pacemaker (InSync Sentry or Concerto, Medtronic, Minneapolis, MN,USA) with two intracardiac leads|DEVICE: Triple-site cardiac resynchronization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Black Widow Spider Antivenin for Patients With Systemic Latrodectism
Status: COMPLETED
Conditions: Latrodectism
Interventions: DRUG: Analatro|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Opioid Free VS Opioid Anesthesia for Craniotomies
Status: COMPLETED
Conditions: Supratentorial Neoplasms
Interventions: DRUG: Opioid free anesthetics|DRUG: Opioid Anesthetics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Gut Microbiota Reconstruction in the Treatment of Irritable Bowel Syndrome With Predominant Diarrhea
Status: UNKNOWN
Conditions: Irritable Bowel Syndrome
Interventions: DRUG: Rifaximin|PROCEDURE: Fecal microbiota transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessing How the Viscosity of Submucosal Gel Injections Helps With Endoscopic Mucosal Resections
Status: WITHDRAWN
Conditions: Gastric Cancer|Colon Cancer
Interventions: DRUG: Cook Medical EMR Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Noise Isolation on the Incidence of Moderate to Severe Postoperative Pain
Status: RECRUITING
Conditions: Postoperative Pain
Interventions: DEVICE: Wear noise-cancelling earphones
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Periosteal Pedicle Flap Versus Subepithelial Connective Tissue Graft in Management of Gingival Recession
Status: NOT_YET_RECRUITING
Conditions: Gingival Recession
Interventions: PROCEDURE: SCTG followed by coronally postionting flap|PROCEDURE: periosteal flap followed by coronally postionting flap
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Improvement of Migraine Severity and Frequency With Migraineguard ™
Status: COMPLETED
Conditions: Migraine|Headache
Interventions: DIETARY_SUPPLEMENT: Migraineguard
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Fecal Microbiota Transplantation for Inflammatory Bowel Disease
Status: UNKNOWN
Conditions: Ulcerative Colitis|Crohn Disease|Constipation (Excl Faecal Impaction)
Interventions: BIOLOGICAL: Fecal microbiota transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Ciprofol for the Sedation in Patients Undergoing Hysteroscopy
Status: COMPLETED
Conditions: Ciprofol|Hysteroscopy
Interventions: DRUG: Ciprofol group|DRUG: Propofol group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Investigate Improvement in Physical Function in SF-36 With Vericiguat Compared With Placebo in Participants With Post-COVID-19 Syndrome
Status: NOT_YET_RECRUITING
Conditions: Post-COVID ME/CFS
Interventions: DRUG: Vericiguat Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Natural History of Minimally Symptomatic Nonobstructing Calyceal Stones
Status: UNKNOWN
Conditions: Renal Stone
Interventions: DEVICE: non-contrast MSCT|DEVICE: Abdominal ultrasonography|DIAGNOSTIC_TEST: Urine analysis|DIAGNOSTIC_TEST: Urine culture
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Efficacy of Hyperemesis Gravidarum on Macular Thickness, Corneal Thickness and Intraocular Pressure in Pregnancy
Status: COMPLETED
Conditions: Corneal Dystrophy|Macular Dystrophy|Hyperemesis Gravidarum - Severe
Interventions: DIAGNOSTIC_TEST: Optic coherence tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Single and Multiple Dose of Rodatristat Ethyl in Healthy Adult Subjects to Evaluate the Effect of Food and Safety
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Rodatristat Ethyl|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Paradigm II Trial: PFX Closure System in Subjects With Cryptogenic Stroke, Transient Ischemic Attack, Migraine or Decompression Illness
Status: COMPLETED
Conditions: Foramen Ovale, Patent
Interventions: DEVICE: PFX Closure System
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Evaluate the Efficacy of the Smart Insulin Pen Compared to a Closed Loop System in Patients With Type 1 Diabetes (EBIACE-1)
Status: COMPLETED
Conditions: Type1diabetes
Interventions: DEVICE: InPen Medtronic|DEVICE: Minimed 780G system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of SANGUINATE for the Treatment of Vaso-occlusive Crisis (VOC) in Adult Sickle Cell Disease Patients
Status: COMPLETED
Conditions: Anemia, Sickle Cell
Interventions: DRUG: SANGUINATE 320 mg/kg|DRUG: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Resistance Training and Testosterone After Spinal Cord Injury
Status: COMPLETED
Conditions: Spinal Cord Injury
Interventions: DEVICE: Resistance Training and Testosterone Patches|DRUG: Testosterone Patches
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Trametinib and Navitoclax in Treating Patients With Advanced or Metastatic Solid Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Malignant Solid Neoplasm|Refractory Malignant Solid Neoplasm|Unresectable Malignant Solid Neoplasm
Interventions: PROCEDURE: Biopsy|PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|PROCEDURE: Magnetic Resonance Imaging|BIOLOGICAL: Navitoclax|PROCEDURE: Positron Emission Tomography|DRUG: Trametinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Vildagliptin Compared to Acarbose in Drug Naive Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: vildagliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Omega-3/Omega-6 Fatty Acids in Pre-school Children at Risk for ADHD
Status: UNKNOWN
Conditions: Children With ADHD Symptoms >90th Percentile (FBB-ADHS-V); no Beginning or Completion of Psychotherapeutically or Psychopharmalogical Treatment During the Study
Interventions: DIETARY_SUPPLEMENT: omega-3/omega-6 fatty acids (PUFAs)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: F18 DCFPyL PET/CT in Imaging Participants With Recurrent Prostate Cancer
Status: NO_LONGER_AVAILABLE
Conditions: Prostate Adenocarcinoma|PSA Level Greater Than 0.2|PSA Level Greater Than or Equal to Two|PSA Progression|Recurrent Prostate Carcinoma
Interventions: PROCEDURE: Computed Tomography|RADIATION: Fluorine F 18 DCFPyL|OTHER: Laboratory Biomarker Analysis|PROCEDURE: Positron Emission Tomography
Study Type: EXPANDED_ACCESS
Clinical trial: Intraoperative Lidocaine Infusion and Surgery-induced Release of Pro-inflammatory Cytokines After Abdominal Surgery
Status: RECRUITING
Conditions: Enhanced Recovery After Surgery
Interventions: DRUG: normal saline group|DRUG: lidocaine group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Two Strategies of Discharge Planning for the Reduction of Short Term Hospital Readmissions
Status: COMPLETED
Conditions: Patient Discharge
Interventions: OTHER: On Demand Discharge Planning (DDP)|OTHER: Routine Discharge Planning (RDP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Evaluation of Dexmedetomidine on Post-operative Narcotic Requirements and Pain Scores in Bariatric Patients
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Dexmedetomidine|DRUG: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Phase 2 Study With Enzastaurin Plus Chemotherapy or Placebo Plus Chemotherapy for Prostate Cancer Patients
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: enzastaurin|DRUG: placebo|DRUG: docetaxel|DRUG: prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transcranial Alternating Current Stimulation (tACS) on Serotonin-1A Receptor in Depression
Status: RECRUITING
Conditions: Major Depressive Disorder
Interventions: DEVICE: tACS|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: THE PHYSIOLOGICAL EFFECTS OF ELECTROMAGNETIC EMISSIONS ON THE GENERAL CONDITION OF THE PATIENT
Status: COMPLETED
Conditions: Electromagnetic Emissions and Emotional Disorder|Electromagnetic Emissions and Medication Savings
Interventions: DEVICE: The emission of electromagnetic with the probes|DEVICE: The emission of electromagnetic without the probes
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Comparison of the Effects of Liquid Vaseline and Olive Oil on Itching and Scarring in Scald Burns
Status: RECRUITING
Conditions: Scald Burn|Itching|Hypertrophic Scarring
Interventions: OTHER: Experimental I liquid vaseline groups|OTHER: Experimental II extra virgin olive oil groups|OTHER: Control Croup
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Low-Intensity Extracorporeal Shockwave Therapy and Vacuum Erectile Device as a Treatment for Peyronies Disease.
Status: UNKNOWN
Conditions: Peyronie Disease
Interventions: DEVICE: low-intensity extracorporeal shockwave therapy|DEVICE: Placebo LI-ESWT|DEVICE: Penile pump
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Supervised (BRACE) Balance, Resistance, Aerobic &Cognitive Exercises
Status: COMPLETED
Conditions: Elderly Population
Interventions: OTHER: Supervised (BRACE) Group|OTHER: Conventional Balance Exercises Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Thiotepa and TEPA Drug Exposure in Pediatric Hematopoietic Stem Cell Transplant Patients
Status: COMPLETED
Conditions: Hematologic Malignancies|Nonmalignant Diseases|Immune Deficiency|Hemoglobinopathies|Genetic Inborn Errors of Metabolism|Fanconi Anemia|Thalassemia|Sickle Cell Disease
Interventions: DRUG: Thiotepa
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Detection of Pulmonary Embolism With Low-dose CT Pulmonary Angiography
Status: COMPLETED
Conditions: Embolism, Pulmonary
Interventions: RADIATION: Computed tomography pulmonary angiography|RADIATION: Computed tomography pulmonary angiography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Physical Performance and Analgesic Effects of tDCS in Primary Dysmenorrhea
Status: COMPLETED
Conditions: Transcranial Direct Current Stimulation|Dysmenorrhea Primary|Pain|Mental Disorders|Physical Fitness
Interventions: DEVICE: Active Transcranial Direct Current Stimulation|DEVICE: Sham Transcranial Direct Current Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Preemptive Analgetic Potency of Low Dose S-Ketamine
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: S-Ketamine|OTHER: Placebo Comparison
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dexmedetomidine and Propofol in the Treatment of Emergence Agitation
Status: UNKNOWN
Conditions: Emergence Agitation
Interventions: DRUG: Dexmedetomidine|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prone Positioning and High-flow Nasal Cannula in COVID-19 Induced ARDS
Status: UNKNOWN
Conditions: COVID|ARDS|Acute Respiratory Distress Syndrome|Acute Respiratory Failure|Corona Virus Infection
Interventions: OTHER: Prone position
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Azithromycin Plus Chloroquine Versus Sulfadoxine-Pyrimethamine Plus Chloroquine For The Treatment Of Uncomplicated, Symptomatic Falciparum Malaria In Southeast Asia
Status: TERMINATED
Conditions: Malaria, Falciparum
Interventions: DRUG: Azithromycin/Chloroquine|DRUG: Sulfadoxine-Pyrimethamine/Chloroquine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Study of Dato-DXd Plus Pembrolizumab vs Pembrolizumab Alone in the First-line Treatment of Subjects With Advanced or Metastatic NSCLC Without Actionable Genomic Alterations
Status: RECRUITING
Conditions: Metastatic Non Small Cell Lung Cancer
Interventions: DRUG: Datopotamab Deruxtecan|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Biomoleculars Markers of Sensitivity to Pre- and Post-operative Chemotherapy of Gastric and Cardia Adenocarcinomas: a Pilot Study
Status: RECRUITING
Conditions: Gastric and Cardia Adenocarcinomas
Interventions: PROCEDURE: Biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: SPI-2012 vs Pegfilgrastim in Management of Neutropenia in Breast Cancer Participants With Docetaxel and Cyclophosphamide
Status: COMPLETED
Conditions: Neutropenia|Breast Cancer
Interventions: DRUG: SPI-2012|DRUG: Pegfilgrastim|DRUG: Docetaxel|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Valacyclovir in Pain Management of Acute Apical Abscesses
Status: RECRUITING
Conditions: Acute Apical Abscess|Pain, Acute
Interventions: DRUG: Valacyclovir 500 MG|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Gentamicin Bladder Instillation on CAUTI
Status: RECRUITING
Conditions: Catheter Infection
Interventions: DRUG: Gentamicin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: An Adaptive Study to Match Patients With Solid Tumors to Various Immunotherapy Combinations Based Upon a Broad Biomarker Assessment
Status: COMPLETED
Conditions: Advanced Cancer
Interventions: BIOLOGICAL: Nivolumab|BIOLOGICAL: Relatlimab|BIOLOGICAL: Cabiralizumab|BIOLOGICAL: Ipilimumab|DRUG: IDO1 Inhibitor|RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GALLANT 7 Tesaglitazar Add-on to Sulphonylurea
Status: TERMINATED
Conditions: Type 2 Diabetes
Interventions: DRUG: Tesaglitazar 0.5 or 1 mg|DRUG: Glibenclamide 2.5, 5, 10 or 15 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Medial Unicondylar Knee Arthroplasty vs Total Knee Arthroplasty
Status: ACTIVE_NOT_RECRUITING
Conditions: Osteoarthritis, Knee
Interventions: PROCEDURE: Unicondylar Knee Arthroplasty|PROCEDURE: Total Knee Arthroplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study to Treat Advanced Malignant Glioma
Status: COMPLETED
Conditions: Advanced Malignant Glioma
Interventions: DRUG: AMG 102 at 20 mg/kg|DRUG: AMG 102 at 10 mg/kg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Demonstrate the Equivalent Pharmacokinetic Properties of a Single Intravenous Dose of HD201 and EU-Herceptin® and US-Herceptin® in Healthy Male Subjects
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: HD201|DRUG: EU-Herceptin|DRUG: US-Herceptin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SCREENING
Clinical trial: Effects of Aerobic Exercise and Core Muscle Strengthening on Pain, Menstrual Pattern and QOL in Endometriosis
Status: COMPLETED
Conditions: Endometriosis
Interventions: OTHER: Aerobic Exercises with core Muscle strengthening|OTHER: Aerobic Exercise without Core Muscle Strengthening
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Utility of [F-18] fluoroDOPA for Neonatal Hyperinsulinism
Status: COMPLETED
Conditions: Congenital Hyperinsulinism|Hyperinsulinism|Persistent Hyperinsulinemic Hypoglycemia of Infancy|CHI|PHHI
Interventions: DRUG: F-DOPA|RADIATION: PET scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Gemcitabine, Oxaliplatin and Panitumumab in Kras/B-raf Wild-Type Biliary Track and Gallbladder Cancer
Status: COMPLETED
Conditions: Biliary Tract Cancer|Gallbladder Cancer
Interventions: DRUG: Panitumumab|DRUG: oxaliplatin|DRUG: gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open-label Multicenter Phase 1 Study of TBI 302 as Second-Line Therapy in Patients With Hepatocellular Carcinoma
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma
Interventions: BIOLOGICAL: TBI 302
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Liposomal Lidocaine Gel for Oral Topical Anesthesia
Status: COMPLETED
Conditions: Anesthesia
Interventions: DRUG: Lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH