pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Aztreonam Lysine for Inhalation in Patients With Cystic Fibrosis and Pseudomonas Aeruginosa Airway Infection
Status: APPROVED_FOR_MARKETING
Conditions: Cystic Fibrosis|Pseudomonas Aeruginosa Airway Infection
Interventions: DRUG: Aztreonam Lysine for Inhalation
Study Type: EXPANDED_ACCESS
Clinical trial: A Study to Explore the Utility of Fractional Exhaled Nitric Oxide (FeNO) Compared With Methacholine Challenge (MCC) Testing in the Assessment of Patients With Suspected But Undiagnosed Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DEVICE: NIOX MINO® Instrument (09-1100)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety Evaluation of EASYEF® in Acute Wound (Split-thickness Skin Graft Donor Site)
Status: COMPLETED
Conditions: Skin Graft Scar|Split-Thickness Skin Graft (STSG)
Interventions: DRUG: rhEGF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study to Characterize Bile Acid Metabolism and Dysbiosis in Primary Sclerosing Cholangitis
Status: COMPLETED
Conditions: Primary Sclerosing Cholangitis|Inflammatory Bowel Disease
Interventions: DRUG: Vancomycin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety and Efficacy of ABI-009 (Nab-rapamycin) in Combination With Pomalidomide and Dexamethasone for Relapsed and Refractory Multiple Myeloma
Status: WITHDRAWN
Conditions: Multiple Myeloma
Interventions: DRUG: ABI-009|DRUG: Pomalidomide|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety and Efficacy Study for Tapentadol (CG5503) Extended Release for Patients With Painful Diabetic Peripheral Neuropathy
Status: COMPLETED
Conditions: Diabetic Neuropathy
Interventions: DRUG: CG5503|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II Trial of Sacituzumab Govitecan in Recurrent and/or Metastatic Secretory Gland Cancers
Status: RECRUITING
Conditions: Gland|Salivary Gland Cancers
Interventions: DRUG: Sacituzumab Govitecan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PCT of Pharmacopuncture Therapy for Chronic Low Back Pain : A Pilot Study
Status: COMPLETED
Conditions: Chronic Low-back Pain
Interventions: PROCEDURE: pharmacopuncture therapy|PROCEDURE: physical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety/Efficacy Study of Seqirus A/H7N9 IIV With or Without MF59(R) Adjuvant to Prevent Avian Influenza
Status: COMPLETED
Conditions: Avian Influenza|Influenza Immunisation
Interventions: BIOLOGICAL: A/H7N9|DRUG: MF59|OTHER: Phosphate Buffered Saline (PBS) diluent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Dose, Safety, and Pathogenicity of a New Influenza B Strain
Status: RECRUITING
Conditions: Influenza B
Interventions: BIOLOGICAL: influenza B/Connecticut/1/21 virus part a dose arm 1|BIOLOGICAL: influenza B/Connecticut/1/21 virus part a dose arm 2|BIOLOGICAL: influenza B/Connecticut/1/21 virus part b dose 1|BIOLOGICAL: influenza B/Connecticut/1/21 virus part b dose 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Vitamin D Supplementation in Chronic Stable Heart Failure
Status: COMPLETED
Conditions: Heart Failure|Vitamin D Deficiency
Interventions: DRUG: Cholecalciferol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety of Butantan Quadrivalent Influenza Vaccine (Split Virion, Inactivated) in Infants and Children .
Status: RECRUITING
Conditions: Influenza, Human
Interventions: BIOLOGICAL: Quadrivalent Influenza Vaccine (split virion, inactivated)|BIOLOGICAL: Trivalent Influenza Vaccine (split virion, inactivated) containing Influenza B virus - Victoria lineage|BIOLOGICAL: Trivalent Influenza Vaccine (split virion, inactivated) containing Influenza B virus - Yamagata lineage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: SGN-35 in CD30-positive Lymphoproliferative Disorders (ALCL), Mycosis Fungoides (MF), and Extensive Lymphomatoid Papulosis (LyP)
Status: ACTIVE_NOT_RECRUITING
Conditions: CD-30 Positive Anaplastic Large T-cell Cutaneous Lymphoma|Lymphoma, Primary Cutaneous Anaplastic Large Cell|Lymphomatoid Papulosis|Mycosis Fungoides|Skin Lymphoma|Cutaneous Lymphomas|Lymphoma|Hematologic Disorder
Interventions: DRUG: SGN-35
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BOTOX® at the Time of Prolapse Surgery for OAB
Status: UNKNOWN
Conditions: Urinary Bladder, Overactive|Pelvic Organ Prolapse
Interventions: DRUG: OnabotulinumtoxinA 100 UNT|OTHER: Injectable saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Vaginal and Intramuscular Progesterone in Vitrified-warmed Blastocyst Transfer Cycles
Status: WITHDRAWN
Conditions: Infertility
Interventions: DRUG: Vaginal progesterone gel (Crinone® 8%)|DRUG: Intramuscular Progesterone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Platelet Rich Plasma Injections In Young And Old Human Subjects
Status: NOT_YET_RECRUITING
Conditions: Osteoarthritis|Articular Cartilage|Musculoskeletal Disorders
Interventions: DRUG: Platelet-Rich Plasma (PRP) Injections|DEVICE: Centrifuge
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Disulfiram for Treatment of Retinal Degeneration
Status: RECRUITING
Conditions: Inherited Retinal Dystrophy Primarily Involving Sensory Retina
Interventions: DRUG: Disulfiram 250 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Management of Cancer Therapy Related Vulvovaginal Atrophy
Status: COMPLETED
Conditions: Genitourinary Syndrome of Menopause
Interventions: DEVICE: Platelet rich plasma|DEVICE: non cross-linked hyaluronic acid|DEVICE: topical HA gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment Of Alcohol Withdrawal Syndrome: Dexmedetomidine Vs Diazepam In A Hospital O'horán
Status: COMPLETED
Conditions: Alcohol Withdrawal Delirium
Interventions: DRUG: Dexmedetomidine 0.004 MG/ML|DRUG: Diazepam Injectable Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the OtoBand in Subjects With Self-reported Vertigo to Reduce Severity of Vertigo in a Real-world Setting
Status: UNKNOWN
Conditions: Vertigo
Interventions: DEVICE: Otoband|DEVICE: Sham A|DEVICE: Sham B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Probiotics on Nasopharyngeal Microbiome of Children With Otitis Media With Effusion
Status: COMPLETED
Conditions: Otitis Media With Effusion|Probiotics|Adenoid Vegetations
Interventions: DIETARY_SUPPLEMENT: Probactiol Mini
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Preoperative Ondansetron Lozenge for Prevention of Postoperative Nausea and Vomiting in Pediatrics Undergoing Squint Surgeries
Status: RECRUITING
Conditions: Ondansetron Lozenge|Postoperative Nausea and Vomiting|Pediatrics|Squint
Interventions: DRUG: Ondansetron lozenge
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparison of Blood Levels of HTL0016878 From an Oral Capsule and an Oral Solution
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: HTL0016878.HCl Solution 10 mg|DRUG: HTL0016878.Citrate Capsule 10 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Chemotherapy With or Without Second-Look Surgery Followed by Radiation Therapy With or Without Peripheral Stem Cell Transplantation in Treating Patients With Intracranial Germ Cell Tumors
Status: COMPLETED
Conditions: Brain Tumor|Central Nervous System Tumors|Childhood Germ Cell Tumor
Interventions: DRUG: carboplatin|DRUG: etoposide|DRUG: ifosfamide|DRUG: thiotepa|PROCEDURE: adjuvant therapy|PROCEDURE: conventional surgery|PROCEDURE: neoadjuvant therapy|PROCEDURE: peripheral blood stem cell transplantation|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Research on Body Voice AI Recognition System for Children's Health Management
Status: NOT_YET_RECRUITING
Conditions: Congenital Heart Disease|Bronchopneumonia|Abdominal Disease
Interventions: DIAGNOSTIC_TEST: Heart Auscultation and Echocardiography|DIAGNOSTIC_TEST: Chest Auscultation and Chest imaging examinations|DIAGNOSTIC_TEST: Abdominal Auscultation and Abdominal imaging examinations
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The PartoMa Project: For Improving Monitoring, Action and Triage During Labour
Status: COMPLETED
Conditions: Obstetric Labor Complications|Stillbirth|Maternal Death
Interventions: OTHER: The PartoMa intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Basket Trial in Solid Tumors Harboring a Fusion of FGFR1, FGFR2 or FGFR3- (FUZE Clinical Trial)
Status: TERMINATED
Conditions: Solid Tumor
Interventions: DRUG: Debio 1347
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Complex And Simple Appendicitis: REstrictive or Liberal Post-operative Antibiotic eXposure (CASA RELAX) - Atrium Health
Status: RECRUITING
Conditions: Appendicitis Surgery
Interventions: OTHER: Antibiotic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exploring the Effectiveness and Safety of Amino Acid Peritoneal Dialysis Solution
Status: RECRUITING
Conditions: Exploring the Effectiveness and Safety of Amino Acid Peritoneal Dialysis Solution in Improving Nutritional Status of Maintenance Peritoneal Dialysis Patients
Interventions: DRUG: Amino acid peritoneal dialysis solution
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Measuring the Effects of Patient Data for Total Hip and Total Knee Arthroplasty Patients Using an APP Based Sensor for Home Exercise Performance Before and After Operation
Status: WITHDRAWN
Conditions: Arthroplasty, Replacement, Hip|Arthroplasty, Replacement, Knee|Clinical Outcome|Patient Satisfaction|Treatment Cost
Interventions: DEVICE: OrthoPath|DEVICE: Control
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect tDCS of Motor Cortex on Chemotherapy Induced Peripheral Neuropathy
Status: UNKNOWN
Conditions: Chemotherapy-induced Peripheral Neuropathy
Interventions: DEVICE: transcranial dirrect current brain stimuation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Therapeutic Effects of Transplantation of MNV-BM-BLD in Pediatric Patients With Pearson Syndrome
Status: COMPLETED
Conditions: Mitochondrial Diseases|Pearson Syndrome
Interventions: BIOLOGICAL: CD34+ cells enriched with MNV-BLD
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Glutamine on Systemic Inflammation During Human Experimental Endotoxemia
Status: COMPLETED
Conditions: Sepsis|Systemic Inflammation
Interventions: DIETARY_SUPPLEMENT: alanine-glutamine infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Improvement and Mechanism of Wheel-chair Music Aerobic Exercise on Depression and Insomnia Among the Elderly in Long-term Care Facilities
Status: UNKNOWN
Conditions: Wheel-chair Dependent Elders
Interventions: OTHER: Original lifestyle|OTHER: Wheel-chair music aerobic exercise (WC-MAE)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Retrospective Study to Capture Dosing and Treatment Outcome Data in Participants With Severe Congenital Protein C Deficiency Who Were Treated With Protein C Concentrate Under an Emergency Use IND
Status: COMPLETED
Conditions: Protein C Deficiency
Interventions: DRUG: Protein C Concentrate (Human) Vapor Heated
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Dental and Periodontal Changes Following the Acceleration of Alignment of Crowded Lower Anterior Teeth Using a Surgical Technique
Status: COMPLETED
Conditions: Crowding, Tooth
Interventions: PROCEDURE: PAOO|OTHER: Fixed appliance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Amphotericin B Suspension in Refractory Chronic Sinusitis
Status: COMPLETED
Conditions: Chronic Sinusitis
Interventions: DRUG: SinuNase
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Occlusal-proximal ART Restorations in Primary Molars Using 2 Different Kinds of GIC
Status: UNKNOWN
Conditions: Dental Caries
Interventions: PROCEDURE: Occlusal-proximal ART restorations - Ketac Molar|PROCEDURE: Occlusal-proximal ART restorations - Vitro Molar
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Swim up and Gradient Methods Used in Assisted Reproduction Techniques on DNA Fragmentation of Spermatozoa
Status: COMPLETED
Conditions: Male Infertility|Unexplained Infertility
Interventions: PROCEDURE: swim-up, density gradient sperm preparation techniques
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Evaluate the Efficacy of Xlear vs. Placebo for Acute COVID-19 Infection
Status: WITHDRAWN
Conditions: Covid19
Interventions: DRUG: Xlear Nasal Spray|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Adalimumab to Methotrexate and Placebo in Subjects With Moderate to Severe Chronic Plaque Psoriasis
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: adalimumab|DRUG: MTX|DRUG: placebo adalimumab, placebo MTX
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: COGNIFOOD-Changing the Carbohydrate/Fat-ratio to Prevent Cognitive Decline and Alzheimer Pathology: A Pilot Study
Status: RECRUITING
Conditions: Prodromal Alzheimer's Disease|Alzheimer Disease|Mild Cognitive Impairment|Neurocognitive Disorders
Interventions: OTHER: LCHF|OTHER: HCLF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Docetaxel, Androgen Ablation, and External-Beam Radiation Therapy in Patients With High-Risk Localized Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: docetaxel|DRUG: leuprolide acetate|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Safety and Immunogenicity of a TB Vaccine; MVA85A, in Healthy Volunteers Who Are Infected With HIV
Status: COMPLETED
Conditions: Tuberculosis|HIV Infections
Interventions: BIOLOGICAL: MVA85A (TB vaccine)|BIOLOGICAL: MVA 85A
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Randomized Trial for Pain Management in Low-grade Subarachnoid Hemorrhage
Status: TERMINATED
Conditions: Headaches Associated With Subarachnoid Hemorrhage (SAH)
Interventions: DRUG: Low dose fentanyl PCA|DRUG: Standard IV fentanyl bolus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Single-arm Trial of the Flow Diverter (Tonbridge) For Endovascular Treatment of Intracranial Aneurysms
Status: RECRUITING
Conditions: Intracranial Aneurysm
Interventions: DEVICE: Flow Diverter (Tonbridge)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mindful-life: Mindfulness Based Intervention vs Cognitive Behavioral Therapy in Patients With Breast Cancer
Status: UNKNOWN
Conditions: Breast Cancer|Depressive Symptoms
Interventions: BEHAVIORAL: Mindfulness Based Intervention|BEHAVIORAL: Cognitive Behavioral Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Image Assisted Optimization of Proton Radiation Therapy in Chordomas and Chondrosarcomas
Status: RECRUITING
Conditions: Bone Neoplasm of Vertebral Column|Chordoma|Chondrosarcoma|Magnetic Resonance Imaging|PET-CT|Proton Therapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Preoperative Gabapentin for Post-tonsillectomy Pain in Children
Status: COMPLETED
Conditions: Post Operative Pain Management in Children With Tonsillectomy/Adenoidectomy
Interventions: DRUG: Gabapentin|DRUG: liquid placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Exercise-based Program for Rehabilitation of Veterans With Severe Mental Illness
Status: RECRUITING
Conditions: Schizophrenia|Schizoaffective|Bipolar Disorder 1
Interventions: OTHER: Yoga-based Exercise (YE)|OTHER: Wellness Lifestyle Program (WLP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Kinesiotape on Postural Control in Non-operated Anterior Cruciate Ligament Subjects
Status: UNKNOWN
Conditions: Knee Injuries|Cruciate Ligament Rupture|Anterior Cruciate Ligament Injuries|Motor Control|Balance
Interventions: DEVICE: Kinesiotape|DEVICE: Sham Bandage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Anti-CD19/CD22 Bispecific CAR-T Cell Therapy for CD19-positive ALL
Status: UNKNOWN
Conditions: CD19-positive ALL
Interventions: BIOLOGICAL: anti-CD19/CD22 CAR-T cells|DRUG: Fludarabine|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ABX-EGF as Second Line Treatment of Advanced Non-Small-Cell Lung Cancer (NSCLC)
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer|Neoplasm Metastasis|Lung Cancer
Interventions: DRUG: ABX-EGF
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 1, Dose Escalation Study of the Safety, Tolerability, and Pharmacokinetics of Intravenous Dimethane Sulfonate (DMS612) in Advanced Malignancies
Status: COMPLETED
Conditions: Renal Cell Carcinoma|Breast Cancer|Colon Cancer|Lung Cancer|Non-Hodgkin Lymphoma
Interventions: DRUG: DMS 612
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Clinical Study of Unilateral or Bilateral Implantation of Intraocular Lens in Cataract Patients
Status: UNKNOWN
Conditions: Cataract
Interventions: DEVICE: unilateral implantation of IOL|DEVICE: bilateral implantation of IOL
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ivermectin in the Treatment of Head Lice
Status: COMPLETED
Conditions: Lice Infestations
Interventions: DRUG: ivermectin|DRUG: malathion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial for Relapsed or Refractory AML Patients Combining Cytarabine and Mitoxantrone With Venetoclax (RELAX)
Status: ACTIVE_NOT_RECRUITING
Conditions: Relapsed Adult AML|Refractory AML
Interventions: DRUG: Venetoclax Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Study to Evaluate the Impact of MTP-131 (Bendavia™) on Skeletal Muscle Function in Elderly
Status: COMPLETED
Conditions: Skeletal Muscle Mitochondrial Dysfunction in the Elderly
Interventions: DRUG: Elamipretide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Gut Microbiota-dependent Health Impacts of Haskap Berries
Status: NOT_YET_RECRUITING
Conditions: Metabolic Disease|Inflammation|Microbial Colonization
Interventions: DIETARY_SUPPLEMENT: Haskap berry smoothie|DIETARY_SUPPLEMENT: Placebo comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Flexibly adding-on Second Antimuscarinic Agent to the First Antimuscarinics for Refractory Overactive Bladder Syndrome
Status: COMPLETED
Conditions: Overactive Bladder
Interventions: DRUG: Detrusitol 4mg QD and Oxybutynin ER 5mg QD|DRUG: Detrusitol 4mg QD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Coronary Artery Disease Management Using Multislice Computed Tomography and Magnetic Resonance Imaging
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: PROCEDURE: CT/MR|PROCEDURE: Catheterization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Stepped Care Model for the Wider Dissemination of Cognitive-Behavioural Therapy for Insomnia Among Cancer Patients
Status: COMPLETED
Conditions: Insomnia
Interventions: BEHAVIORAL: Professionally-administered cognitive-behavioral therapy for insomnia (CBT-I)|BEHAVIORAL: Web-based cognitive-behavioral therapy for insomnia (CBT-I)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Aripiprazole Lauroxil (Also Known as ARISTADA TM) in Subjects With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Aripiprazole Lauroxil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pembrolizumab Plus Docetaxel for the Treatment of Recurrent or Metastatic Head and Neck Cancer
Status: COMPLETED
Conditions: Head and Neck Carcinoma
Interventions: DRUG: Docetaxel|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Electrical Activity Tibial Muscle and Postural Control of Individuals With Hemiparesia Post TDCS Associated With FES
Status: UNKNOWN
Conditions: Hemiparesis|Transcranial Direct Current Stimulation|Electromyography
Interventions: DEVICE: Transcranial direct current stimulation (tDCS)|DEVICE: Functional electrical stimulation (FES)|DEVICE: Sham stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of Raloxifene to Induce Ovulation in Polycystic Ovarian Syndrome
Status: TERMINATED
Conditions: Polycystic Ovarian Syndrome
Interventions: DRUG: Raloxifene|DRUG: Clomiphene
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy Selection Based on Therapeutic Targets for Advanced Pancreatic Cancer
Status: UNKNOWN
Conditions: Carcinoma, Pancreatic Ductal
Interventions: DRUG: Targeted Therapy Tailored Treatment|DRUG: Standard Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pain Management in Pediatric Adenotonsillectomy
Status: NOT_YET_RECRUITING
Conditions: Pain Management
Interventions: DRUG: Tramadol 5%|DRUG: Lidocaine 2%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ultrasound (US)-Guided Versus Sham Ultrasound Corticosteroid (CS) Knee Injections
Status: TERMINATED
Conditions: Osteoarthritis
Interventions: PROCEDURE: Ultrasound|PROCEDURE: Sham ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Oral Semaglutide Versus Dulaglutide Both in Combination With One OAD (Oral Antidiabetic Drug) in Japanese Subjects With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: Semaglutide|DRUG: Dulaglutide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of TQ-B3525 Tablets Combined With Fulvestrant Injection in Subjects With HR-positive, HER2-negative and PIK3CA Mutation Advanced Breast Cancer
Status: UNKNOWN
Conditions: HR-positive, HER2-negative and PIK3CA Mutation Advanced Breast Cancer
Interventions: DRUG: TQ-B3525|DRUG: Fulvestrant injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Ischemic Preconditioning on Atrial Fibrillation After Electrocardioversion
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: PROCEDURE: Remote ischemic preconditioning|PROCEDURE: Sham preconditioning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Concurrent Chemoradiotherapy for Stage IVB Esophageal Squamous Cell Carcinoma（EC-CRT-003）
Status: RECRUITING
Conditions: Metastatic Esophageal Squamous Cell Carcinoma
Interventions: COMBINATION_PRODUCT: Intensity-modulated radiotherapy concurrent with capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Of Pregabalin In Subjects With Post-Stroke Central Neuropathic Pain
Status: COMPLETED
Conditions: Central Neuropathic Pain
Interventions: DRUG: Pregabalin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Study to Evaluate BMS-830216 in Healthy Subjects
Status: COMPLETED
Conditions: Obesity
Interventions: DRUG: BMS-830216|DRUG: Placebo|DRUG: BMS-830216|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dose Escalation TTHX1114 Ophthalmic Solution
Status: COMPLETED
Conditions: Corneal Epithelial Degeneration
Interventions: DRUG: TTHX1114(NM141) Ophthalmic Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Efficacy and Safety of SHR-2010 Injection in the Treatment of Primary IgA Nephropathy
Status: RECRUITING
Conditions: Primary IgA Nephropathy
Interventions: DRUG: SHR-2010 Injection|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study on Optimizing Follow-up for Postmenopausal Women With Breast Cancer Treated With Adjuvant Endocrine Therapy
Status: COMPLETED
Conditions: Breast Cancer
Interventions: BEHAVIORAL: Individualized, tailored follow-up program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Naldebain for Control of Post-Cesarean Section Pain
Status: UNKNOWN
Conditions: Post Operative Pain, Acute|Post Operative Pain, Chronic|Cesarean Section
Interventions: DEVICE: Patient-controlled epidural analgesia (PCEA)|DRUG: Naldebain®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Safety and Effectiveness of Didanosine Plus Stavudine Plus Delavirdine Mesylate Plus MKC-442 in HIV-Infected Patients Who Have Not Had Success With Protease Inhibitors
Status: TERMINATED
Conditions: HIV Infections
Interventions: DRUG: Emivirine|DRUG: Hydroxyurea|DRUG: Delavirdine mesylate|DRUG: Stavudine|DRUG: Didanosine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of MR-107A-02 for the Treatment of Acute Postoperative Pain Following Bunionectomy
Status: RECRUITING
Conditions: Acute Pain|Post Operative Pain|Pain
Interventions: DRUG: MR-107A-02|DRUG: Tramadol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Polatuzumab Vedotin (Pola) Plus Rituximab (R) in Patients With Post-transplant Lymphoproliferative Disorder (PTLD)
Status: RECRUITING
Conditions: Post-transplant Lymphoproliferative Disorder
Interventions: DRUG: Polatuzumab vedotin|DRUG: Rituximab|DRUG: CHP
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Safety and Efficiency of Sirolimus in Primary Antiphospholipid Syndrome: A Randomized Control Study
Status: NOT_YET_RECRUITING
Conditions: Primary Antiphospholipid Syndrome
Interventions: DRUG: Sirolimus|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intraluminal Therapy for Helicobacter Pylori Infection
Status: COMPLETED
Conditions: Helicobacter Pylori Infection
Interventions: DRUG: Lansoprazole|DRUG: Amoxicillin|DRUG: Clarithromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Improving Postamputation Functioning by Decreasing Phantom Pain With Perioperative Continuous Peripheral Nerve Blocks: A Department of Defense Funded Multicenter Study
Status: ENROLLING_BY_INVITATION
Conditions: Lower Extremity Surgical Amputation|Post-amputation Phantom Limb Pain
Interventions: DRUG: Experimental continuous peripheral nerve blocks|DRUG: Control continuous peripheral nerve blocks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Tanzberger Versus Pelvic Floor Muscle Exercises on Urinary Incontinence
Status: COMPLETED
Conditions: Urinary Incontinence|Menopause
Interventions: OTHER: Tanzberger Exercises|OTHER: Pelvic floor muscle training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Tolerability of Propiverine Hydrochloride in Patients With Neurogenic Detrusor Overactivity
Status: COMPLETED
Conditions: Neurogenic Urinary Bladder Disorder|Urinary Bladder, Neurogenic|Bladder Disorder, Neurogenic|Urinary Bladder Disorder, Neurogenic|Neurogenic Bladder Disorder|Urinary Bladder Neurogenic Dysfunction|Urologic Diseases|Overactive Detrusor Function|Urinary Incontinence
Interventions: DRUG: Propiverine hydrochloride ER (extended release)|DRUG: Propiverine hydrochloride IR (immediate release)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Low Speed Drilling Versus Conventional Drilling Technique on Crestal Bone Level in Maxilla.(Group B ) A Randomized Controlled Clinical Trial
Status: UNKNOWN
Conditions: Bone Resorption
Interventions: PROCEDURE: Drilling at low speed|PROCEDURE: Drilling at conventional or high speed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of Ketoconazole on Breathlessness
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: ketoconazole|DRUG: inert powder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Short-term Survival of Subjects With Acute-on-chronic Liver Failure After Plasma Exchange With Human Serum Albumin 5%
Status: RECRUITING
Conditions: Acute-On-Chronic Liver Failure
Interventions: BIOLOGICAL: SMT + PE-A 5%|OTHER: Standard Medical Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Onyx™ Trial For The Embolization Of The Middle Meningeal Artery For Chronic Subdural Hematoma (OTEMACS)
Status: RECRUITING
Conditions: Hematoma, Subdural, Chronic|Brain Diseases|Central Nervous System Diseases|Wounds and Injuries
Interventions: DEVICE: Middle Meningeal Artery Embolization|PROCEDURE: Standard Management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Scapular Stabilization and Thoracic Extension Exercises in Patients With Scapular Dyskinesis
Status: COMPLETED
Conditions: Scapular Dyskinesis
Interventions: OTHER: Scapular stabilization exercises with conventional therapy|OTHER: Thoracic extension exercises with conventional therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Safety and Effectiveness of Bone Marrow Transplants in Children With Sickle Cell Disease (BMT CTN 0601)
Status: COMPLETED
Conditions: Sickle Cell Disease
Interventions: BIOLOGICAL: Hematopoietic Stem Cell Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single-arm, Open-label Clinical Study of SZ011 in the Treatment of Advanced Triple Negative Breast Cancer
Status: NOT_YET_RECRUITING
Conditions: Advanced Triple Negative Breast Cancer
Interventions: DRUG: SZ011 CAR-NK
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of DisCoVisc and Hydroxypropylmethylcellulose 2%
Status: COMPLETED
Conditions: Corneal Edema|Intraocular Pressure
Interventions: DRUG: Hyaluronic Acid and hydroxypropylmethylcellulose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Hypertrophic Cardiomyopathy Under Stress Conditions. Concordance Between Two Complementary Tests: Stress MRI and Exercice Stress Echocardiography
Status: UNKNOWN
Conditions: Hypertrophic Cardiomyopathy
Interventions: OTHER: Diagnosis examens
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effectiveness of High-intensity Interval Training (HIIT) Versus Moderate-intensity Continuous Training (MICT) in Reducing Visceral Fat in Adults With Central Obesity
Status: WITHDRAWN
Conditions: Central Obesity
Interventions: BEHAVIORAL: Usual care control group|BEHAVIORAL: HIIT group|BEHAVIORAL: MICT group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Non-Comparative Study of Open Abdomen That Require the Use of Negative Pressure Wound Therapy (NPWT) for Temporary Abdominal Closure
Status: WITHDRAWN
Conditions: Abdomenal Wound Trauma
Interventions: DEVICE: RENASYS® TOUCH Negative Pressure Wound Therapy (NPWT) Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ApoA-I Synthesis Stimulation and Intravascular Ultrasound for Coronary Atheroma Regression Evaluation
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DRUG: RVX000222|DRUG: Placebo RVX000222
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Integrated Care Involving Peripheral Functional Magnetic Stimulation for Sarcopenia
Status: NOT_YET_RECRUITING
Conditions: Sarcopenia
Interventions: DEVICE: Peripheral functional magnetic stimulation (ISKRA MEDICAL TESLA Former prestige Magneto therapy)|DIETARY_SUPPLEMENT: Nutritional supplementation (ENSURE HIGH CALCIUM)|BEHAVIORAL: Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Project RESIST: Evaluating the Effects of Anti-smoking Inoculation Messages Among Young Adult Sexual Minority Women
Status: COMPLETED
Conditions: Cigarette Smoking Behavior
Interventions: OTHER: Culturally Tailored Anti-Smoking Messages
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Transversus Abdominis Plane Block Versus Paravertebral Block for Post Operative Pain Relief in Open Renal Surgeries
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: PROCEDURE: Thoracic paravertebral block|PROCEDURE: Transversus abdominis plane block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Effect of Lung Protective One-lung Ventilation With Fix and Variable PEEP on Oxygenation and Outcome
Status: COMPLETED
Conditions: Hypoxemia|Pulmonary Sepsis|ARDS, Human|Pneumonia
Interventions: OTHER: Change of ventilatory settings
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Clinical Study of Pegylated Somatropin (PEG Somatropin) to Treat SGA Children With Short Stature
Status: UNKNOWN
Conditions: Small for Gestational Age Infant
Interventions: BIOLOGICAL: PEG-somatropin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Safety and Long-term Prognosis of Imatinib in Patients Newly Diagnosed With Chronic Myelogenous Leukemia (Chronic Phase)
Status: COMPLETED
Conditions: Chronic Myelogenous Leukemia in Chronic Phase
Interventions: DRUG: Imatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: FOLFOXIRI Compared With FOLFIRI for Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: FOLFIRI|DRUG: FOLFOXIRI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: LYT-100 in Patients With Idiopathic Pulmonary Fibrosis (IPF)
Status: ACTIVE_NOT_RECRUITING
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: DRUG: Placebo|DRUG: Pirfenidone|DRUG: Deupirfenidone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Different Methods of Enamel Preparation Before Pit and Fissure Sealants
Status: COMPLETED
Conditions: Enamel Lesions|Dental Caries
Interventions: PROCEDURE: air abrasion|PROCEDURE: sono abrasion|PROCEDURE: dental bur
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effects of Air Pollution Exposure Reduction by Filter Mask on Heart Failure
Status: COMPLETED
Conditions: Exposure to Pollution|Heart Failure
Interventions: OTHER: Filtered diesel exhaust|OTHER: Unfiltered diesel exhaust|OTHER: Clean air
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Atezolizumab After Concurrent Chemo-radiotherapy Versus Chemo-radiotherapy Alone in Limited Disease Small-cell Lung Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Small-cell Lung Cancer
Interventions: DRUG: Atezolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Experimental Headache Induced by Vasoactive Intestinal Polypeptide
Status: COMPLETED
Conditions: Healthy Volunteers, Headache, Migraine, Hemodynamics, VIP, SPECT, Ultrasound
Interventions: DRUG: VIP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: DIAGNOSTIC
Clinical trial: Saliva Irisin Level is Higher and Related With Interleukin 6 in Generalized Periodontitis
Status: COMPLETED
Conditions: Inflammatory Response|Periodontitis
Interventions: OTHER: Samples collection and ELISA analyses|DIAGNOSTIC_TEST: Evaluating periodontal paramètres
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Three Alternative Drug Regimens for Malaria Seasonal Preventive Treatment in Senegal
Status: COMPLETED
Conditions: Malaria
Interventions: DRUG: sulfalene-pyrimethamine plus amodiaquine|DRUG: dihydroartemisinin plus piperaquine|DRUG: sulfadoxine pyrimethamine plus piperaquine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Indinavir Plus Efavirenz Plus Adefovir Dipivoxil in HIV-Infected Patients Who Have Not Had Success With Nelfinavir
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Indinavir sulfate|DRUG: Efavirenz|DRUG: Levocarnitine|DRUG: Adefovir dipivoxil
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Venous to Arterial Carbon Dioxide Difference (P₍ᵥ-ₐ₎CO₂): Predictor of Septic Patient Prognosis Depending on the ScvO₂
Status: COMPLETED
Conditions: Septic Shock
Interventions: OTHER: measure of the SOFA score
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Maxillary Third Molar Extraction vs. Non-extraction on Distalization of First Molars in a Group of Adolescent Patients
Status: COMPLETED
Conditions: Class II Malocclusion
Interventions: PROCEDURE: Distalization combined with upper third molars extraction|PROCEDURE: Distalization without upper third molars extraction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Outcomes With Umbilical Cord Allograft for Musculoskeletal Conditions Musculoskeletal Conditions
Status: NOT_YET_RECRUITING
Conditions: Osteoarthritis|Tendinitis|Sports Injury|Degenerative Disc Disease|Degenerative Arthritis|Ligament Injury|Neuropathy|Pelvic Pain
Interventions: OTHER: Umbilical Allograft
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT