pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Nasal Intermittent Positive-Pressure Ventilation for Twin Infants With Respiratory Distress Syndrome
Status: COMPLETED
Conditions: Neonatal Respiratory Distress Syndrome
Interventions: DEVICE: nIPPV|DEVICE: nCPAP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Low-Dose Pioglitazone in Patients With NASH (AIM 2)
Status: RECRUITING
Conditions: Type 2 Diabetes Mellitus (T2DM)|Nonalcoholic Steatohepatitis
Interventions: DRUG: Pioglitazone|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Should Chronic Stimulant Medications be Continued Preoperatively in Patients With Attention Deficit Hyperactivity Disorder(ADHD)
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: DRUG: Amphetamine and/or methylphenidate|OTHER: Hold stimulant medication
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Clopidogrel and Clarithromycin on the Oral Disposition of Sibutramine in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Sibutramine-clopidogrel|DRUG: sibutramine-Clarithromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: GSK1349572 Exposure in Blood, Cervicovaginal Fluid, and Cervical and Vaginal Tissue in Healthy Female Subjects
Status: COMPLETED
Conditions: Healthy Adult Females
Interventions: DRUG: GSK1349572 (dolutegravir)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: First in Human Dose Escalation Study of Vactosertib (TEW-7197) in Subjects With Advanced Stage Solid Tumors
Status: COMPLETED
Conditions: Advanced Stage Solid Tumors
Interventions: DRUG: TEW-7197
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Mechanisms of Oral Probiotics in Preventing Necrotizing Enterocolitis
Status: UNKNOWN
Conditions: Necrotizing Enterocolitis|Death
Interventions: DIETARY_SUPPLEMENT: probiotics|DIETARY_SUPPLEMENT: glucose solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Phase I/II Study of SRP-4053 in DMD Patients
Status: COMPLETED
Conditions: Duchenne Muscular Dystrophy
Interventions: DRUG: Placebo|DRUG: SRP-4053
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Controlled Study of Steroids Plus Cyclosporin Therapy for Patients of Idiopathic Membranous Nephropathy
Status: UNKNOWN
Conditions: Idiopathic Membranous Nephropathy|Proteinuria|Spontaneous Remission|Steroid Nephropathy|Cyclosporin Overdose
Interventions: DRUG: steroid & Cyclosporin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Virtual Reality in Hazmat Training
Status: COMPLETED
Conditions: No Disease or Condition is Being Studied|Evaluating a Brief Intervention|Does Virtual Reality Aid in Hazmat Training
Interventions: BEHAVIORAL: Classroom Training|BEHAVIORAL: Virtual Reality Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Phase 1a Study in Healthy Participants
Status: NOT_YET_RECRUITING
Conditions: Healthy
Interventions: DRUG: HS-10506|DRUG: HS-10506 Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Study to Assess the Safety, PK, and PD in SBS-IF Subjects
Status: RECRUITING
Conditions: Short Bowel Syndrome
Interventions: DRUG: HM15912 Active|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: New Ischemic Cerebral Lesions After Endarterectomy vs. Stenting for the Treatment of Symptomatic Carotid Stenosis
Status: TERMINATED
Conditions: Carotid Artery Stenosis|Carotid Atherosclerosis|Stroke, Ischemic
Interventions: PROCEDURE: Carotid Artery Stenting|PROCEDURE: Endarterectomy carotid artery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Point-of-care Ultrasound Guidance for Distal Radius Fracture Reduction
Status: COMPLETED
Conditions: Point-of-care Ultrasound, Distal Radius Fracture
Interventions: DEVICE: Point-of-care ultrasound|PROCEDURE: Closed fracture reduction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Respiratory Exercise to Copd With Virtual Reality Glasses on Dyspnea, Anxiety and Qualıty of Life
Status: COMPLETED
Conditions: Copd|Breathing Exercises
Interventions: OTHER: Breathing exercise application with virtual reality glasses|OTHER: routine treatment and care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Efficacy of NTX-001 Compared to SOC in Acute Single Peripheral Nerve Injuries
Status: ACTIVE_NOT_RECRUITING
Conditions: Peripheral Nerve Injuries
Interventions: COMBINATION_PRODUCT: NTX-001
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Availability of Berry Phytonutrients Post-consumption of Fresh and Processed Blueberry by Healthy Adults
Status: UNKNOWN
Conditions: Healthy
Interventions: OTHER: a non-traditional (i.e., not typically available in the supermarket) blueberry cultivar bred using natural plant breeding techniques and established as having enhanced nutritive value|OTHER: a standard commercially available blueberry variety (i.e., cultivar)|OTHER: a "minimally processed" blueberry-rich protein bar|OTHER: a control beverage of matched-nutritive content
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Vitamin D Supplementation for Acute Bronchiolitis
Status: COMPLETED
Conditions: Bronchiolitis
Interventions: DRUG: Cholecalciferol|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Laparoscopic Cholecystectomy And Capacitive Coupling - Coag Versus Blend Mode Causing Thermal Injury at Port Site Skin
Status: COMPLETED
Conditions: Intraoperative Complications|Thermal Injury|Electrocoagulation
Interventions: DEVICE: Covidien Triad monopolar generator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Compare the Bioequivalence of 50-mg Tapentadol (CG5503) Dose Administered as Two 25-mg Tablets Relative to One 50-mg Tablet
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: tapentadol (CG5503) ER 25-mg TRF|DRUG: tapentadol (CG5503) ER 50-mg TRF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: A Study to Investigate the Safety, Tolerability, PK, PD, and Efficacy of ONO-7018 in Patients With R/R NHL or CLL
Status: RECRUITING
Conditions: Lymphoma, Non-Hodgkin|Leukemia, Lymphocytic, Chronic, B-Cell
Interventions: DRUG: ONO-7018|DRUG: ONO-7018
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acute Effect of a Standardized Botanical Blend Rich in Polyphenols on Cognitive Functions in Healthy Students
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: SBRP|DIETARY_SUPPLEMENT: PLACEBO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Study to Learn How Safe the Study Treatment Actinium-225-macropa-pelgifatamab (BAY3546828) is, How it Affects the Body, How it Moves Into, Through and Out of the Body, and About Its Anticancer Activity in Men With Advanced Metastatic Castration-resistant Prostate Cancer (mCRPC)
Status: RECRUITING
Conditions: Metastatic Castration-resistant Prostate Cancer
Interventions: DRUG: BAY3546828|DRUG: BAY2616505|DRUG: BAY2315493
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Ultrasound-guided Hydrodilatation With Hyaluronic Acid for Patients With Adhesive Capsulitis
Status: COMPLETED
Conditions: Adhesive Capsulitis
Interventions: DRUG: hyaluronic acid (hyruan)|OTHER: physical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Automatic Self Transcending Meditation (ASTM) in Patients With Dry Eye Disease
Status: UNKNOWN
Conditions: Eye Diseases|Quality of Life|Depression|Anxiety
Interventions: OTHER: Automatic Self Transcending Meditation (ASTM)|OTHER: Treatment as Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pharmacokinetics of Two Eletriptan Oral Formulations Given With and Without Water and the Commercial Tablet Formulation Given With Water
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Commercial tablet with water|DRUG: ODT #1 without water|DRUG: ODT #2 without water|DRUG: ODT #1 with water|DRUG: ODT #2 with water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Real Life Effectiveness in Asthma of Symbicort Single Inhaler Therapy
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Budesonide/formoterol|DEVICE: Symbicort® Turbohaler®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of rTMS in Bipolar Depression
Status: TERMINATED
Conditions: Bipolar Depression
Interventions: DEVICE: iTBS repetitive Transcranial Magnetic Stimulation (rTMS)|DEVICE: Sham rTMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Red Blood Cell Transfusion Thresholds for Improved Quality of Life for Patients Undergoing a Pancreatectomy for Pancreatic Cancer
Status: RECRUITING
Conditions: Resectable Pancreatic Carcinoma
Interventions: BIOLOGICAL: Arm I Packed Red Blood Cell Transfusion (Hgb < 7 g/dL)|BIOLOGICAL: Arm II Packed Red Blood Cell Transfusion (Hgb < 9 g/dL)|PROCEDURE: Computed Tomography|PROCEDURE: X-Ray Imaging|PROCEDURE: Biospecimen Collection|OTHER: Survey Administration|PROCEDURE: Pancreatectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: HyperHAES Versus Placebo - Effect on Intracranial Pressure in SAH Patients
Status: COMPLETED
Conditions: Subarachnoid Hemorrhage
Interventions: DRUG: 7.2% NaCl in 6% hydroxyethyl starch solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Autogenous Dentin Graft in Treatment of Infra-bony Defect
Status: COMPLETED
Conditions: Periodontitis (Stage 3)
Interventions: PROCEDURE: Autogenous demineralized dentin nanoparticles
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Intra-bone Cord Blood Transplantation
Status: UNKNOWN
Conditions: Hematologic Neoplasms
Interventions: PROCEDURE: Intrabone injection|BIOLOGICAL: Intra-bone cord blood hematopoietic stem cell transplantation|BIOLOGICAL: Intra-bone cord blood hematopoietic stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Dose-ranging Pharmacokinetics and Safety Study of GWP42003-P in Children With Dravet Syndrome (GWPCARE1)
Status: COMPLETED
Conditions: Epilepsy|Dravet Syndrome
Interventions: DRUG: GWP42003-P 5 mg/kg/day Dose|DRUG: Placebo control|DRUG: GWP42003-P 10 mg/kg/day Dose|DRUG: GWP42003-P 20 mg/kg/day Dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bladder Perforation Post-TURBT: Definition, Incidence and Natural HistoryStudy
Status: UNKNOWN
Conditions: Bladder Cancer|Bladder Urothelial Carcinoma|Trauma|Injuries|Perforation of Bladder|Recurrence Tumor|Resection Margin|Seeding, Neoplasm
Interventions: DIAGNOSTIC_TEST: Computed tomographic cystography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluating the Impact of an Equity Focused Dashboard and Clinical Support
Status: COMPLETED
Conditions: Hypertension|Diabetes|Breast Cancer
Interventions: OTHER: Equity Dashboard, Population Health Coordinator and Community Health Worker Support|OTHER: Equity Dashboard and Population Health Coordinator Support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Feasibility Controlled Trial of an 8-session Group Intervention for Siblings of Children Who Have ASD
Status: COMPLETED
Conditions: Autism Spectrum Disorder
Interventions: OTHER: Sibling support group|OTHER: None - control condition
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low Intensity Resistance Training With Partial Blood Flow Restriction for Quadriceps Strengthening
Status: COMPLETED
Conditions: Knee Osteoarthritis|Symptomatic Knee Osteoarthritis
Interventions: OTHER: partial blood flow restriction|OTHER: Low intensity exercise without partial blood flow restriction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: House Dust Mite Allergen Reduction in Bedding: Purotex Impregnated Covers of Bekaert Textiles
Status: COMPLETED
Conditions: Allergic Rhinitis
Interventions: OTHER: use of Purotex treated bedding covers|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Identification of the Lumbar Interspinous Spaces; Palpation Versus Ultrasound Versus Fluoroscopy
Status: UNKNOWN
Conditions: Accuracy of Identifying the Intralaminar Space
Interventions: PROCEDURE: identification of the lumbar interspinous space using fluoroscopy versus ultrasound versuspalpation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Human Papilloma Virus (HPV) Vaccine Trial in Young Adolescent Women With GlaxoSmithKline Biologicals' (GSK Bio) HPV-16/18 Vaccine
Status: COMPLETED
Conditions: Cervical Intraepithelial Neoplasia|Papillomavirus Infection
Interventions: BIOLOGICAL: GSK Biologicals' HPV-16/18 Vaccine (Cervarix™)|BIOLOGICAL: Havrix™
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Work Rate Adjustments During a High-intensity Interval Training on a Stationary Bike in a Hot and Temperate Environment
Status: COMPLETED
Conditions: High-Intensity Interval Training|Heat
Interventions: BEHAVIORAL: 15 minutes of high-intensity interval training|BEHAVIORAL: 43 minutes of high-intensity interval training|OTHER: Hot environment|OTHER: Temperate environment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Determinants of Balance in Patients With Chronic Obstructive Pulmonary Disease
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: OTHER: Balance Assessment|OTHER: Pulmonary function test|OTHER: Respiratory muscle strength test|OTHER: Peripheral muscle strength test|OTHER: 6-minute walk test|OTHER: Cognitive assessment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phono- and Electrocardiogram Assisted Detection of Valvular Disease
Status: COMPLETED
Conditions: Aortic Valve Stenosis|Mitral Regurgitation|Heart Murmurs|Valvular Heart Disease
Interventions: DIAGNOSTIC_TEST: AS Algorithm 1|DIAGNOSTIC_TEST: AS Algorithm 2|DIAGNOSTIC_TEST: MR Algorithm 1|DIAGNOSTIC_TEST: MR Algorithm 2
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Treatment of Port Wine Stains Using Pulsed Dye Laser, Erbium Yag Laser and Topical Sirolimus
Status: TERMINATED
Conditions: Port-Wine Stain
Interventions: DRUG: Sirolimus|OTHER: Erbium yag laser|DEVICE: Pulsed Dye Laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Rizatriptan for the Treatment of Acute Migraine in Patients on Topiramate for Migraine Prophylaxis
Status: COMPLETED
Conditions: Migraine
Interventions: DRUG: rizatriptan benzoate|DRUG: Comparator: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Value of Lymph Node Dissection of Indocyanine Green-guided Near-infrared Fluorescent Imaging in Esophagectomy
Status: UNKNOWN
Conditions: Esophageal Cancer|Indocyanine Green
Interventions: DRUG: Indocyanine green solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Efficacy of Microsomal Triglyceride Protein (MTP) Inhibitor
Status: COMPLETED
Conditions: Homozygous Familial Hypercholesterolemia
Interventions: DRUG: Lomitapide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I Trial of Intratumoral pIL-12 Electroporation in Malignant Melanoma
Status: COMPLETED
Conditions: Malignant Melanoma
Interventions: BIOLOGICAL: IL-12p DNA|PROCEDURE: Intratumoral Electroporation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Open-Label, Dose-Escalation Study of IMC-20D7S In Participants With Malignant Melanoma
Status: COMPLETED
Conditions: Malignant Melanoma
Interventions: BIOLOGICAL: IMC-20D7S (Cohort 1A)|BIOLOGICAL: IMC-20D7S (Cohort 2A)|BIOLOGICAL: IMC-20D7S (Cohort 3A)|BIOLOGICAL: IMC-20D7S (Cohort 4A)|BIOLOGICAL: IMC-20D7S (Cohort 1B)|BIOLOGICAL: IMC-20D7S (Cohort 2B)|BIOLOGICAL: IMC-20D7S (Cohort 3B)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CAR20.19.22 T-cells in Relapsed, Refractory B-cell Malignancies
Status: ACTIVE_NOT_RECRUITING
Conditions: B-cell Non Hodgkin Lymphoma|B-cell Chronic Lymphocytic Leukemia
Interventions: BIOLOGICAL: 0.75x10^6 cells/kg CAR20.19.22 cells|BIOLOGICAL: 1x10^6 cells/kg CAR20.19.22 cells|BIOLOGICAL: 2.5x10^6 cells/kg CAR20.19.22 cells|BIOLOGICAL: 5x10^6 cells/kg CAR20.19.22 cells|BIOLOGICAL: Dose expansion: The maximum tolerated dose of CAR20.19.22 cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multicultural Healthy Diet to Reduce Cognitive Decline
Status: COMPLETED
Conditions: Diet Modification|Cognitive Decline|Cognitive Change
Interventions: OTHER: Multicultural Healthy Diet|OTHER: Usual Diet plus Self-Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Preoperative Transhepatic Arterial Chemotherapy (TAC) in the Treatment of Liver Metastasis of Resectable Colorectal Cancer
Status: UNKNOWN
Conditions: Colorectal Cancer
Interventions: DRUG: tac + folfox4|DRUG: folfox4
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a 4mmx32G Pen Needle for Injection of Basal Insulin Doses Above 40 Units
Status: TERMINATED
Conditions: Diabetes Mellitus, Type 2
Interventions: DEVICE: 4 mm x 32G pen needle (Nano)|DEVICE: 8mm x 31G pen needle (Short)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Anti-TF Antibody (ALT-836) to Treat Septic Patients With Acute Lung Injury or Acute Respiratory Distress Syndrome
Status: COMPLETED
Conditions: Sepsis|Acute Lung Injury|Acute Respiratory Distress Syndrome
Interventions: DRUG: ALT-836|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ranibizumab for Branch Retinal Vein Occlusion Associated Macular Edema Study (RABAMES)
Status: COMPLETED
Conditions: Macular Edema
Interventions: DRUG: Ranibizumab|PROCEDURE: Laser photocoagulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tissue Expander/Implant Reconstruction: A Single-Blinded, Randomized, Controlled Trial
Status: COMPLETED
Conditions: Breast Cancer
Interventions: PROCEDURE: Alloderm, Questionnaires|PROCEDURE: Without ALLODERM, Questionnaires
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Lovastatin in Severe Persistent Asthma
Status: WITHDRAWN
Conditions: Severe Persistent Asthma
Interventions: DRUG: Lovastatin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of B013 and Nab-Paclitaxel for Locally Advanced or Metastatic Triple Negative Breast Cancer
Status: RECRUITING
Conditions: Triple Negative Breast Cancer (TNBC)
Interventions: DRUG: B013+Nab-Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Metformin 750 mg Tablets XR Versus Glucophage® Long 750 mg Tablets XR In Normal Healthy Subjects Under Fasting and Fed Conditions
Status: COMPLETED
Conditions: Bioequivalence
Interventions: DRUG: Metformine|DRUG: Glucophage® Long|DRUG: Metformin|DRUG: Glucophage® Long
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Guided Bone Regeneration Using Polydioxanone (PDO) Membrane in Sockets After Tooth Extraction
Status: NOT_YET_RECRUITING
Conditions: Surgery, Oral
Interventions: DEVICE: Plenum® Guide|DEVICE: Plenum® Oss|PROCEDURE: Tooth extraction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Formerly Abducted Children (FAC) in Uganda
Status: COMPLETED
Conditions: Stress Disorders, Post-Traumatic
Interventions: BEHAVIORAL: Narrative Exposure Therapy|BEHAVIORAL: Academic Counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Statins in Patients With Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Simvastatin|DRUG: Lactose tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety of One Dose of Meningococcal ACWY Conjugate Vaccine in Subjects From 2 Months to 55 Years of Age in the Republic of South Korea
Status: COMPLETED
Conditions: Meningococcal Disease
Interventions: BIOLOGICAL: MenACWY-CRM (Menveo)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: High Fresh Gas Flow After Intubation
Status: COMPLETED
Conditions: Atelectasis
Interventions: PROCEDURE: Control group, conventional ventilatory settings|PROCEDURE: High fresh gas flow, high minute ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Reliability of Paired Associative Stimulation-induced Neuroplasticity After Stroke
Status: TERMINATED
Conditions: Stroke
Interventions: BEHAVIORAL: PAS true|BEHAVIORAL: PAS sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Using Intravenous Heparin Versus Standard of Care Subcutaneous Heparin to Prevent Clots After Surgery
Status: COMPLETED
Conditions: Venous Thrombosis
Interventions: DRUG: low dose intravenous heparin (LDIVH)|DRUG: Heparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Topical Application of Low-concentration (0.01%) Atropine on the Human Eye With Fast and Slow Myopia Progression Rate
Status: COMPLETED
Conditions: Myopia
Interventions: DRUG: Atropine (0.01%)|DRUG: Artificial tear
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Prucalopride Prior to Small Bowel Capsule Endoscopy
Status: UNKNOWN
Conditions: Gastrointestinal Hemorrhage|Crohn Disease|Celiac Disease|Intestinal Diseases|Inflammatory Bowel Diseases
Interventions: DRUG: Prucalopride|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Analysis of Biological Characteristics of Advanced ALK-rearranged NSCLC
Status: RECRUITING
Conditions: Non-small Cell Lung Cancer|ALK Gene Rearrangement Positive
Interventions: GENETIC: RNAseq
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Safety of Faster-acting Insulin Aspart Compared to NovoRapid® Both in Combination With Insulin Degludec in Adults With Type 1 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 1
Interventions: DRUG: Faster-acting insulin aspart|DRUG: insulin aspart|DRUG: insulin degludec
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Postoperative Pain With Eddy Tips (EPPET)
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: DRUG: 5,25% NaOCl with syringe needle irrigation alone|DEVICE: EDDY
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Peer Intervention to Improve Access Among Rural Women Veterans With Psychological Distress and Unmet Social Needs
Status: ACTIVE_NOT_RECRUITING
Conditions: Psychological Distress|Depression|PTSD|Anxiety
Interventions: OTHER: Personalized Support for Progress (PSP)|OTHER: Tailored Referral (TR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: CeraVe Cream Compared to Desitin Paste for Treating Diaper Dermatitis in Infants
Status: TERMINATED
Conditions: Diaper Rash
Interventions: DRUG: CeraVe Baby Diaper Rash Cream|DRUG: Desitin Maximum Strength Original Paste
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Pembrolizumab (MK-3475) in Combination With Belzutifan (MK-6482) and Lenvatinib (MK-7902), or Pembrolizumab/Quavonlimab (MK-1308A) in Combination With Lenvatinib, Versus Pembrolizumab and Lenvatinib, for Treatment of Advanced Clear Cell Renal Cell Carcinoma (MK-6482-012)
Status: ACTIVE_NOT_RECRUITING
Conditions: Carcinoma, Renal Cell
Interventions: BIOLOGICAL: Pembrolizumab|DRUG: Belzutifan|BIOLOGICAL: Pembrolizumab/Quavonlimab|DRUG: Lenvatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects Of Oral Prednisolone On Bone Metabolism In Patients With Chronic Obstructive Pulmonary Disease
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: prednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Genetic Polymorphisms of Interleukin-10 and TNF-α on Outcome of HCV-Related Chronic Liver Disease
Status: UNKNOWN
Conditions: Hepatitis C Virus Infection|Chronic Liver Disease
Interventions: GENETIC: TNF-alpha and IL-10
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose:
Clinical trial: Investigating the Therapeutic Effectiveness of Aloe Barbadensis in Reducing Cutaneous Side-Effects of Radiation Treatment for Breast Cancer.
Status: COMPLETED
Conditions: Breast Cancer
Interventions: PROCEDURE: Aloe barbadensis topical application in a moisturizing cream vehicle.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Safety and Tolerability of Trivalent Influenza Virus Vaccine in Children Aged 5 Years to < 9 Years
Status: COMPLETED
Conditions: Influenza, Human
Interventions: BIOLOGICAL: bioCSL Trivalent Influenza Virus Vaccine (CSL TIV)|BIOLOGICAL: Comparator Quadrivalent Influenza Virus Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Ixabepilone in Treating Patients With Relapsed and/or Refractory Stage III or Stage IV Ovarian Epithelial or Primary Peritoneal Cancer
Status: COMPLETED
Conditions: Ovarian Cancer|Peritoneal Cavity Cancer
Interventions: DRUG: ixabepilone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Piezosurgery in the Treatment of Class II Furcation Involvement
Status: UNKNOWN
Conditions: Furcation Defects
Interventions: PROCEDURE: Piezosurgery with biomaterial mp3 + bracket|PROCEDURE: Piezosurgery with biomaterial mp3|PROCEDURE: Piezosurgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Best Medical Treatment Versus Best Medical Treatment Plus Renal Artery Stenting
Status: COMPLETED
Conditions: Renal Artery Stenosis
Interventions: DEVICE: Dynamic Renal Stent plus Best Medical Treatment|DRUG: Best Medical Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics and Safety of ALKS 5461 in Subjects With Renal Impairment and Normal Renal Function
Status: COMPLETED
Conditions: Renal Impairment
Interventions: DRUG: ALKS 5461
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Furmonertinib in EGFR-Mutant, PD-L1+ Patients With Locally Advanced or Metastatic NSCLC (FUTURE)
Status: RECRUITING
Conditions: Non-Small-Cell Lung Cancer
Interventions: DRUG: Furmonertinib (160mg)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Knee Osteoarthritis (OA) Project Treatment Versus Conventional Physical Therapy in the Treatment of Knee OA Patients
Status: UNKNOWN
Conditions: Osteoarthritis, Knee
Interventions: OTHER: knee OA project|OTHER: conventional PT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Hypertonic Saline on Mucus Clearance in Children Ages 5-12 With Cystic Fibrosis
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: Hypertonic Saline|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: AZD6140 Oral Contraceptive Interaction Study
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: AZD6140|DRUG: Levonorgestrel and Ethinyl Estradiol (Nordette®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Artemisinin to Reduce The Symptoms of Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder
Interventions: DIETARY_SUPPLEMENT: Artemisinin|DIETARY_SUPPLEMENT: Identical looking placebo capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Diet and Systemic Inflammation
Status: COMPLETED
Conditions: Low-grade Chronic Inflammation|Intestinal Permeability|Type 2 Diabetes Mellitus|Cardiovascular Disease|Obesity
Interventions: OTHER: Fructose-sweetened beverages|OTHER: Glucose-sweetened beverages|OTHER: High-fructose corn syrup-sweetened beverages
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Dipeptidyl Peptidase- 4 Inhibitors on Non-Alcoholic Steatohepatitis and Type 1 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1|NASH
Interventions: DRUG: Dipeptidyl peptidase 4 (DPP-4) inhibitor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The VITAL Amyloidosis Study, a Global Phase 3, Efficacy and Safety Study of NEOD001 in Patients With AL Amyloidosis
Status: TERMINATED
Conditions: Primary Systemic (AL) Amyloidosis
Interventions: DRUG: NEOD001|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Preoperative Ferric Carboxymaltose After Simultaneous Bilateral Total Knee Arthroplasty
Status: UNKNOWN
Conditions: Postoperative Anemia|Knee Osteoarthritis|Total Knee Arthroplasty
Interventions: DRUG: Ferric carboxymaltose|DRUG: 0.9% Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Using Neurofeedback to Understand the Relationship Between Stress and Alcohol Consumption
Status: NOT_YET_RECRUITING
Conditions: Alcohol Abuse|Craving|Psychosocial Stressor|Neural Stress Response
Interventions: BEHAVIORAL: ScanSTRESS fMRI-paradigm (Streit et al., 2014)|BEHAVIORAL: real-time fMRI neurofeedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Infusion of Allogeneic, 3rd Party CD19-specific T Cells
Status: WITHDRAWN
Conditions: Blood And Marrow Transplantation|Leukemia|Lymphoma
Interventions: DRUG: Cyclophosphamide|DRUG: Fludarabine|PROCEDURE: T-Cell Infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Carbohydrates Part 2
Status: COMPLETED
Conditions: Gastro-Intestinal Tolerance
Interventions: OTHER: CHO Control 1 and 2 Glucose|OTHER: CHO Experimental 1 Slowly Digested|OTHER: CHO Experimental 2 Digestion Resistant|OTHER: CHO Experimental 3 Low Sugar|OTHER: CHO Experimental 4 Maltodextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Comparison of the Effects of QLB 2 and QLB 3 on Post-operative Analgesia in Cesarean Section Surgery
Status: COMPLETED
Conditions: Analgesia|Acute Pain|Chronic Pain
Interventions: OTHER: Regional anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Head Mounted Eye Tracking Aide for Loss of Central Vision (HETALCEV)
Status: COMPLETED
Conditions: Age-related Macular Degeneration
Interventions: OTHER: small scotoma using Head Mounted Display No re-mapping|OTHER: Large scotoma using Head Mounted Display PLUS re-mapping
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Different Sperm Processing Methods in ICSI Outcome.
Status: TERMINATED
Conditions: Sperm DNA Fragmentation
Interventions: PROCEDURE: sperm processing method
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Personalized Autologous Transplant for Multiple Myeloma
Status: RECRUITING
Conditions: Multiple Myeloma
Interventions: PROCEDURE: Autologous Hematopoietic Stem Cell Transplantation|DRUG: Melphalan|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Age Comparisons of Exercising Muscle O2 Supply in Healthy Adults: Effects of Esmolol Infusion
Status: COMPLETED
Conditions: Aging
Interventions: DRUG: Esmolol infusion|DRUG: Saline infusion|OTHER: Pre exercise baseline|OTHER: Isometric handgrip exercise|OTHER: Semi-recumbent cycling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Venticute in Patients With Pneumonia or Aspiration of Gastric Contents and Intubation/Ventilation/Oxygenation Impairment (BY2001/M1-007)
Status: COMPLETED
Conditions: Pneumonia
Interventions: DRUG: Venticute
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy in Treating Patients With Extensive Stage Small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DRUG: cisplatin|DRUG: cyclophosphamide|DRUG: epirubicin hydrochloride|DRUG: etoposide|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Intralesional Steroids in the Treatment of Alopecia Areata
Status: TERMINATED
Conditions: Alopecia Areata
Interventions: DRUG: Intralesional Triamcinolone 2.5 mg/ml|DRUG: Intralesional Triamcinolone 5 mg/ml|DRUG: Intralesional Triamcinolone 10 mg/ml|DRUG: Intralesional Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Feasibility of Transcranial Direct Current Stimulation [tDCS] With Standard Aphasia Therapy
Status: COMPLETED
Conditions: Aphasia|Stroke
Interventions: DEVICE: Anodal transcranial direct current stimulation|DEVICE: Sham transcranial direct current stimulation|BEHAVIORAL: Speech-language therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ketone Ester Supplementation and Nocturnal Blood Pressure
Status: COMPLETED
Conditions: Cardiovascular Diseases in Old Age|Aging|Cardiovascular Diseases|Sleep
Interventions: DIETARY_SUPPLEMENT: Ketone Ester|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase III Study of 2nd-line XELIRI ± Bevacizumab vs. FOLFIRI ± Bevacizumab in mCRC
Status: COMPLETED
Conditions: Colorectal Neoplasms|Neoplasm Metastasis|Intestinal Neoplasms|Gastrointestinal Neoplasms|Digestive System Neoplasms
Interventions: BIOLOGICAL: Bevacizumab|DRUG: CPT-11 (Irinotecan)|DRUG: 5-FU Bolus|DRUG: 5-FU Infusion|DRUG: l-LV (dl-LV)|BIOLOGICAL: bevacizumab|DRUG: CPT-11 (Irinotecan)|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I Study of a Dendritic Cell Vaccine for Patients With Either Newly Diagnosed or Recurrent Glioblastoma
Status: COMPLETED
Conditions: Glioblastoma|Glioblastoma Multiforme|Glioma|Astrocytoma|Brain Tumor
Interventions: BIOLOGICAL: Dendritic cell vaccination, in addition to standard temozolomide chemotherapy and involved field radiation therapy|BIOLOGICAL: Dendritic cell vaccination, with optional bevacizumab treatment for patients previously treated with bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 5-Fluoro-2'-Deoxcyctidine and Tetrahydrouridine to Treat Patients With Advanced Cancer
Status: COMPLETED
Conditions: Neoplasms
Interventions: DRUG: 5-Fluoro-2-Deoxycytidine (FdCyd)|OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacological Study|DRUG: Tetrahydrouridine (THU)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase Ib/II Study of Primary Chemotherapy With Paclitaxel, Gemcitabine, and Sunitinib
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Paclitaxel,Gemcitabine,Sunitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hip Posterolateral Complex Strengthening in Patients With Chronic Nonspecific Low Back Pain: a Randomized Clinical Trial
Status: UNKNOWN
Conditions: Low Back Pain
Interventions: OTHER: Conventional physical therapy plus HPCS|OTHER: Conventional physical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of a Transition Intervention for ALWH
Status: COMPLETED
Conditions: Treatment Adherence
Interventions: OTHER: Community-based accompaniment and home visits|BEHAVIORAL: Directly Observed Therapy|BEHAVIORAL: Monthly Peer Support Groups
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Living Well With Serious Illness "Wicokuje Sica Tuha Akisniya Wiconi": Wawokiya Health Advocate Intervention
Status: RECRUITING
Conditions: Cancer
Interventions: BEHAVIORAL: Wawokiya Health Advocate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Role of the Orexin Receptor System in Stress, Sleep and Cocaine Use
Status: COMPLETED
Conditions: Cocaine Use Disorder|Anxiety
Interventions: DRUG: suvorexant|DRUG: Placebo (for suvorexant)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II Clinical Trial of the Inactivated Rotavirus Vaccine
Status: RECRUITING
Conditions: Rotavirus Infections|Diarrhea
Interventions: BIOLOGICAL: IRV on a 0- and 28-day schedule|BIOLOGICAL: IRV on a 0-, 28- and 56-day schedule|BIOLOGICAL: Placebo on Day 0, 28|BIOLOGICAL: Placebo on Day 0, 28, 56
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: HFCWO on Pneumonic Respiratory Failure
Status: COMPLETED
Conditions: Acute Respiratory Failure|Pneumonia
Interventions: DEVICE: Vest Airway Clearance System Model 105|DEVICE: placebo intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Pharmacokinetic Study of Hepalatide(L47) in Healthy Volunteers
Status: COMPLETED
Conditions: Hepatitis B， Chronic
Interventions: DRUG: Hepalatide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT