pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Study of Magnetic Resonance Image and Computed Tomography-Guided Stereotactic Body Radiation Therapy for Abdominopelvic Sarcomas (MARS Trial)
Status: RECRUITING
Conditions: Abdominopelvic Sarcomas
Interventions: RADIATION: Magnetic Resonance Image and Computed Tomography-Guided Stereotactic Body Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: QUILT-2.017: Phase 1b/2 Study of AMG 479 in Combination With Paclitaxel and Carboplatin for 1st Line Treatment of Advanced Squamous Non-Small Cell Lung Cancer
Status: TERMINATED
Conditions: Advanced Squamous Non-Small Cell Lung Cancer
Interventions: BIOLOGICAL: AMG 479|BIOLOGICAL: AMG 479|DRUG: Carboplatin|BIOLOGICAL: AMG 479|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Trial of a New Infant Formula in Healthy Term Chinese Infants
Status: RECRUITING
Conditions: Healthy Infants
Interventions: OTHER: New infant formula with 6 HMOs blend|OTHER: Standard infant formula without 6 HMOs blend
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Randomized Trial of Telemetry Compared With Unmonitored Floor Admissions in ED Patients With Low-Risk Chest Pain
Status: WITHDRAWN
Conditions: Telemetry Usage|Chest Pain|Unstable Angina|Resource Utilization
Interventions: OTHER: Telemetry|OTHER: Unmonitored
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Comparison of Screening Tests in Detecting Cervical Neoplasia
Status: COMPLETED
Conditions: Cervical Cancer
Interventions: OTHER: Papanicolaou test|OTHER: cytology specimen collection procedure|PROCEDURE: annual screening|PROCEDURE: colposcopic biopsy|PROCEDURE: comparison of screening methods
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: SCREENING
Clinical trial: A Study of GPC3-targeted T Cells by Intratumor Injection for Advanced HCC (GPC3-CART)
Status: UNKNOWN
Conditions: Carcinoma, Hepatocellular
Interventions: DRUG: GPC3-CART cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Modified Collaborative Assessment VS Standard Assessment on Readiness For Psychotherapy Among Patients With Anxiety
Status: ACTIVE_NOT_RECRUITING
Conditions: Psychotherapy|Social Anxiety Disorder|Personality Disorders
Interventions: BEHAVIORAL: Modified Collaborative Assessment (MCA)|BEHAVIORAL: Assessment as Usual (AAU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Pulsed Magnetic Field Versus Low Level Laser Therapy on Functional Performance in Children With Juvenile Idiopathic Arthritis
Status: COMPLETED
Conditions: Juvenile Idiopathic Arthritis
Interventions: DEVICE: pulsed magnetic field|DEVICE: Low level laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of Xevinapant With Cisplatin and Radiation Therapy After Surgery in People With Head and Neck Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Head and Neck Cancer
Interventions: DRUG: Xevinapan|DRUG: Cisplatin|RADIATION: External beam
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stratifying Risk for Intracerebral Haemorrhage
Status: UNKNOWN
Conditions: Preterm Birth|Coagulation Protein Disorders|Coagulation Disorder Neonatal
Interventions: DIAGNOSTIC_TEST: mass spectrometry (LC-MS/MS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of a Candidate Clostridium Difficile Toxoid Vaccine in Subjects at Risk for C. Difficile Infection
Status: TERMINATED
Conditions: Clostridium Difficile Infection
Interventions: BIOLOGICAL: C. difficile Toxoid Vaccine|BIOLOGICAL: Placebo: 0.9% normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pegylated Liposomal Doxorubicin, PD-1 in Treating Muscle Invasive Bladder Cancer
Status: UNKNOWN
Conditions: Muscle Invasive Bladder Cancer
Interventions: DRUG: pegylated liposomal doxorubicin (PLD)|DRUG: PD-1
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Arrhythmogenic Potential of Midwall Septal Fibrosis in Dilated Cardiomyopathy
Status: RECRUITING
Conditions: Dilated Cardiomyopathy
Interventions: DIAGNOSTIC_TEST: ECG-Imaging|DIAGNOSTIC_TEST: Cardiac MRI scan
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety of a Single, Intravitreal Injection of Human Retinal Progenitor Cells (jCell) in Retinitis Pigmentosa
Status: COMPLETED
Conditions: Retinitis Pigmentosa (RP)
Interventions: BIOLOGICAL: human retinal progenitor cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multi-surgery Assessment of ZYNRELEF (HTX-011), AMAZE. Master Protocol HTX-011-401.
Status: ACTIVE_NOT_RECRUITING
Conditions: Analgesia
Interventions: DRUG: Bupivacaine Hydrochloride|DRUG: Bupivacaine Hydrochloride|DRUG: HTX-011|DEVICE: Luer lock applicator|DRUG: Ibuprofen|DRUG: Acetaminophen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: TDCS Effects on Motor Learning and Motor Control in Healthy Subjetcs
Status: COMPLETED
Conditions: Healthy
Interventions: DEVICE: transcranial direct current stimularion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cluster RCT of Cognitive Behavioral Therapy to Support Caregivers of Older Adults in Hong Kong
Status: NOT_YET_RECRUITING
Conditions: Caregiver Burden|Depressive Symptoms|Quality of Life|Self Efficacy|Resilience
Interventions: BEHAVIORAL: Cognitive Behavioral Therapy for Caregivers of Older Adults|BEHAVIORAL: Control intervention for Caregivers of Older Adults
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of the Safety, Tolerability and Pharmacokinetics (PK) of GSK3732394 First-Time-in-Human (FTIH) Study
Status: TERMINATED
Conditions: HIV Infections
Interventions: DRUG: GSK3732394|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Magnetic Resonance Imaging Evaluation of Inner Ear Pathology Using Intra-Tympanic Contrast Agent
Status: COMPLETED
Conditions: Meniere's Disease
Interventions: DRUG: Magnevist (gadopentetate dimeglumine)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: TaxXel: Taxotere and Xeloda in Esophageal Cancer
Status: UNKNOWN
Conditions: Cancer of the Esophagus|Gastric Cardia Carcinoma
Interventions: DRUG: Docetaxel|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Determination of Adequate Tuberculosis Regimen in Patients Hospitalized With HIV-associated Severe Immune Suppression
Status: RECRUITING
Conditions: Tuberculosis|HIV-1-infection|Immuno-Deficiency
Interventions: DRUG: Intensified TB treatment (initial phase)|DRUG: WHO standard TB treatment (initial phase)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mesenchymal Stem Cells In Cisplatin-Induced Acute Renal Failure In Patients With Solid Organ Cancers
Status: WITHDRAWN
Conditions: Solid Tumors|Acute Kidney Injury
Interventions: BIOLOGICAL: Mesenchymal stromal cell infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Extended Carfilzomib Therapy for Patients Previously Enrolled in Carfilzomib Treatment Protocols
Status: COMPLETED
Conditions: Multiple Myeloma|Solid Tumors
Interventions: DRUG: Carfilzomib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chance to Avoid New Caries by Adding Chlorhexidine to the Preventive Protocol in Adolescent Special Needs
Status: COMPLETED
Conditions: Disabilities Multiple
Interventions: BEHAVIORAL: preventive protocol|BEHAVIORAL: chlorhexidine added to the preventive protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Learn How Safe BAY2395840 is and How Well it Works in Participants Who Have Diabetic Nerve Pain
Status: COMPLETED
Conditions: Neuropathic Pain Associated With Diabetic Peripheral Neuropathy|Peripheral Neuropathic Pain|Diabetes Mellitus
Interventions: DRUG: BAY2395840|DRUG: Placebo for BAY2395840
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Outcomes of Tiotropium Plus Fluticasone Propionate/Salmeterol Compared With Tiotropium for Chronic Obstructive Pulmonary Disease (COPD) in Korea
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: tiotropium with fluticasone propionate/salmeterol (FSC)|DRUG: tiotropium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Bioequivalence of the Metformin Component of the Fixed Dose Combination Tablet of Canagliflozin and Metformin Extended Release With Respect to Metformin Extended Release Tablet Coadministered With Canagliflozin in Healthy Fed and Fasted Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Canagliflozin and Metformin Extended Release (XR) Fixed Dose Combination [FDC]|DRUG: Canagliflozin|DRUG: Canagliflozin|DRUG: Metformin Extended Release (XR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Paclitaxel and Carboplatin With or Without Bevacizumab in Treating Patients With Stage II, Stage III, or Stage IV Ovarian Epithelial Cancer, Primary Peritoneal Cancer, or Fallopian Tube Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Fallopian Tube Endometrioid Adenocarcinoma|Fallopian Tube Mucinous Adenocarcinoma|Fallopian Tube Transitional Cell Carcinoma|Ovarian Brenner Tumor|Ovarian Clear Cell Adenocarcinofibroma|Ovarian Endometrioid Adenocarcinoma|Ovarian Mucinous Adenocarcinoma|Ovarian Seromucinous Carcinoma|Ovarian Serous Adenocarcinoma|Ovarian Transitional Cell Carcinoma|Ovarian Undifferentiated Carcinoma|Primary Peritoneal Serous Adenocarcinoma|Stage IIA Fallopian Tube Cancer AJCC v6 and v7|Stage IIA Ovarian Cancer AJCC V6 and v7|Stage IIB Fallopian Tube Cancer AJCC v6 and v7|Stage IIB Ovarian Cancer AJCC v6 and v7|Stage IIC Fallopian Tube Cancer AJCC v6 and v7|Stage IIC Ovarian Cancer AJCC v6 and v7|Stage IIIA Fallopian Tube Cancer AJCC v7|Stage IIIA Ovarian Cancer AJCC v6 and v7|Stage IIIA Primary Peritoneal Cancer AJCC v7|Stage IIIB Fallopian Tube Cancer AJCC v7|Stage IIIB Ovarian Cancer AJCC v6 and v7|Stage IIIB Primary Peritoneal Cancer AJCC v7|Stage IIIC Fallopian Tube Cancer AJCC v7|Stage IIIC Ovarian Cancer AJCC v6 and v7|Stage IIIC Primary Peritoneal Cancer AJCC v7|Stage IV Fallopian Tube Cancer AJCC v6 and v7|Stage IV Ovarian Cancer AJCC v6 and v7|Stage IV Primary Peritoneal Cancer AJCC v7
Interventions: BIOLOGICAL: Bevacizumab|DRUG: Carboplatin|PROCEDURE: Computed Tomography|DRUG: Paclitaxel|PROCEDURE: Therapeutic Conventional Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Specialized Cognitive-Behavioral Counseling Intervention to Reduce HIV Transmission Risk Behavior in HIV-Infected Men
Status: COMPLETED
Conditions: HIV Infections
Interventions: BEHAVIORAL: Cognitive behavioral intervention|BEHAVIORAL: Standard counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Predictive Biomarkers of Biological Activity and Efficacy of Nilotinib on ZAK Target in Non-metastatic Colon Cancer
Status: WITHDRAWN
Conditions: Colon Cancer
Interventions: DRUG: Nilotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study to Evaluate the Immunogenicity and Safety of A Recombinant Protein COVID-19 Vaccine as Booster Vaccines
Status: NOT_YET_RECRUITING
Conditions: COVID-19|SARS-CoV-2 Infection
Interventions: BIOLOGICAL: SCTV01E-2|BIOLOGICAL: SCTV01E
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Granulocyte Colony Stimulating Factor Versus Platelet Rich Plasma and Outcomes of Frozen Embryo Transfer
Status: COMPLETED
Conditions: Infertility
Interventions: DRUG: Granulocyte Colony Stimulating Factor|OTHER: Platelet Rich Plasma Arm|OTHER: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study to Assess the Safety and Effectiveness of Plant-based Biotin and Plant Based Biotin With Silica in Healthy Human Subjects With Complaints of Hair Fall, Thin, Dry, & Brittle Hair, and Dry Skin
Status: RECRUITING
Conditions: Hair Falling|Thin Hair|Dry Hair|Brittle Hair|Dry Skin
Interventions: OTHER: Placebo|DIETARY_SUPPLEMENT: Botanical extract of standardized biotin|DIETARY_SUPPLEMENT: Botanical extract of standardised biotin with silica
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy of Catheter Ablation of Idiopathic Ventricular Arrhythmias Arising From Cardiac Outflow Tracts
Status: WITHDRAWN
Conditions: Ventricular Arrythmia
Interventions: PROCEDURE: Radiofrequency cardiac catheter ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Different I:E Ratio on Intrapulmonary Shunt Fraction and Oxygenation During One Lung Ventilation in the Lateral Decubitus Position
Status: COMPLETED
Conditions: Lung Cancer|Lung Lobectomy
Interventions: PROCEDURE: I:E ratio
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of Single-stage Advanced Versus Rotated Flaps in the Treatment of Gingival Recessions
Status: COMPLETED
Conditions: Gingival Recession
Interventions: PROCEDURE: Test - Laterally positioned flap|PROCEDURE: Control-Coronally positioned flap|DRUG: 750 mg paracetamol|DRUG: chlorhexidine gluconate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Symptom Management Implementation of Patient Reported Outcomes in Oncology
Status: ACTIVE_NOT_RECRUITING
Conditions: Other Cancer|Gastrointestinal Cancer|Thoracic Cancer|Gynecologic Cancer
Interventions: OTHER: eSyM App Usage|OTHER: SASS Questionnaire
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Lenalidomide and Melphalan in Treating Patients With Previously Untreated Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma and Plasma Cell Neoplasm
Interventions: DRUG: dexamethasone|DRUG: lenalidomide|DRUG: melphalan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of a Transcranial Vibrating System for Mitigation of Migraine Associated Vertigo
Status: SUSPENDED
Conditions: Dizziness|Nausea|Headache|Confusion
Interventions: DEVICE: Otoband|DEVICE: Otoband sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Correlation Between Trachebroncho Malacia/Hyperdynamic Airway Collapse And Obstructive Sleep Apnea
Status: COMPLETED
Conditions: Trachebronchomalacia (TBM)|Hyper Dynamic Airway Collapse (HDAC)|Obstructive Sleep Apnea (OSA)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Explore the Effect of Acid-reducing Agents
Status: COMPLETED
Conditions: Healthy Adults
Interventions: DRUG: Sitravatinib|DRUG: Pantoprazole|DRUG: Famotidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Glycemic Rises After Waking Up In Response To An Alarm Clock In Type 1-Diabetic Patients Analysed With Continuous Glucose Monitoring (GlucoDay®)
Status: COMPLETED
Conditions: Stress|Type 1 Diabetes
Interventions: OTHER: Continuous glucose monitoring|OTHER: alarm- clock intervention, patient perform blood glucose self monitoring|OTHER: nurse intervention|OTHER: Taking the patients pulse|OTHER: Venous blood drawing|OTHER: Other capillary sample
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Epinephrine Sprayed on the Papilla Versus Sterile Water Sprayed on the Papilla for Preventing Pancreatitis After Endoscopic Retrograde Cholangiopancreatography
Status: TERMINATED
Conditions: Pancreatitis, Acute
Interventions: DRUG: Epinephrine|OTHER: Sterile water|DRUG: Indomethacin Rectal Suppository
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Prospective Multicenter Study Evaluating Feasibility and Efficacy of Tumor Organoid-based Precision Medicine in Patients With Advanced Refractory Cancers
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced, Pretreated Solid Tumors
Interventions: PROCEDURE: Biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effects of Breastfeeding Education Interventions During Pregnancy on Breastfeeding Practices in Rural South Ethiopia
Status: NOT_YET_RECRUITING
Conditions: Pre-lacteal Feeding|Colostrum Feeding|Early Initiation of Breastfeeding|Exclusive Breastfeeding
Interventions: BEHAVIORAL: Health education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy Study of Nuc-1031 and Carboplatin Combination to Treat Recurrent Ovarian Cancer
Status: COMPLETED
Conditions: Recurrent Ovarian Cancer
Interventions: DRUG: Nuc-1031 and Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Single-Group Study to Examine the Efficacy of a Melatonin Lotion With Magnesium to Improve Sleep Quality and Quantity
Status: COMPLETED
Conditions: Sleep
Interventions: OTHER: Asutra's 'Dream the night away' nighttime lotion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study to Assess the Safety, Tolerability, and Pharmacokinetics of BIIB078 in Adults With C9ORF72-Associated Amyotrophic Lateral Sclerosis
Status: COMPLETED
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DRUG: BIIB078|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Brassica Intake and Isothiocyanate Absorption
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: OTHER: Controlled diet without brassica vegetables|OTHER: Controlled diet with brassica vegetables
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Bortezomib in Treating Patients With Persistent or Recurrent Ovarian Epithelial Cancer or Primary Peritoneal Cancer
Status: COMPLETED
Conditions: Primary Peritoneal Cavity Cancer|Recurrent Ovarian Epithelial Cancer
Interventions: DRUG: bortezomib|OTHER: laboratory biomarker analysis|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Brentuximab Vedotin (SGN-35) in Transplant Eligible Patients With Relapsed or Refractory Hodgkin Lymphoma
Status: COMPLETED
Conditions: Hodgkin's Lymphoma
Interventions: DRUG: brentuximab vedotin (SGN-35)|DRUG: Brentuximab Vedotin (SGN-35)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SCP vs HUSLS for Pelvic Organ Prolapse Repair
Status: ACTIVE_NOT_RECRUITING
Conditions: Pelvic Organ Prolapse|Cystocele|Rectocele|Enterocele
Interventions: PROCEDURE: Robotic sacrocolpopexy|PROCEDURE: high uterosacral ligament suspension
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Telehealth Exercise Intervention to Improve Cardiovascular Health in Lymphoma Survivors, TECHS Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Hodgkin Lymphoma|Non-Hodgkin Lymphoma
Interventions: OTHER: Exercise Intervention|OTHER: Questionnaire Administration|OTHER: Telemedicine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phase 3 Clinical Study of AK112 for NSCLC Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-Squamous Non-small Cell Lung Cancer
Interventions: DRUG: Ivonescimab (SMT112 or AK112) Injection|DRUG: Placebo Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Paravertebral Block vs. General Anesthesia for Major Abdominal Surgery
Status: UNKNOWN
Conditions: Major Abdominal Surgery
Interventions: DRUG: Paravertebral block|DRUG: General anesthesia|PROCEDURE: Major abdominal surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Imaging the Neurobiology of Behavioral and Medication Treatment for Cocaine Dependence
Status: COMPLETED
Conditions: Cocaine Dependence
Interventions: DRUG: levodopa carbidopa and entacapone (LCE)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: H5N1 Vaccination With and Without AS03: Systems Biology Analysis
Status: COMPLETED
Conditions: Influenza
Interventions: DRUG: ASO3 Adjuvant|BIOLOGICAL: Influenza A/H5N1 Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Impact of Disney Movies During Chemotherapy on QOL of Gynecologic Oncology Patients
Status: COMPLETED
Conditions: Ovarian Cancer|Chemotherapy|Quality of Life
Interventions: OTHER: Disney movie|OTHER: EORTC QLQ-C30 and EORTC QLQ-FA12 surveys
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study to Evaluate the Influence of Hydrochlorothiazide on Dermal Photosensitivity and DNA Stability - a Pilot Study (HCTox Study)
Status: COMPLETED
Conditions: Photosensitivity
Interventions: DRUG: Hydrochlorothiazide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Segmental Epidural Anesthesia (SEA) V/S General Anesthesia for PCNL
Status: COMPLETED
Conditions: Success Rate Under Segmental Epidural|Post Operative Pain
Interventions: PROCEDURE: PCNL under General Anesthesia|PROCEDURE: Segmental Epidural Anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: A Study to Evaluate Safety and Immunogenicity of AERAS-402
Status: COMPLETED
Conditions: Tuberculosis
Interventions: BIOLOGICAL: AERAS 402|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Cinnamomum Cassia Effect on IGF1 and Metabolic Control in Patients With DM2 Without Glycemic Control Metformin Treated
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: OTHER: Cinnamomum Cassia|OTHER: Placebo (calcined magnesia)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Efficacy and Safety of Budesonide (PT008) in Adult Subjects With Mild to Moderate Persistent Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: BD MDI 320 µg|DRUG: BD MDI 160 µg|DRUG: BD MDI 80 µg|DRUG: BD MDI 40 µg|DRUG: Placebo MDI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Two Hand Hygiene Products in ICUs
Status: COMPLETED
Conditions: Hand Hygiene Effectiveness
Interventions: DRUG: hand antiseptic with CHG and alcohol|DRUG: Alcohol hand sanitizer foam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Front-line VenObi Combination Followed by Ven or VenZan Combination in Patients With Residual Disease: a MRD Tailored Treatment for Young Patients With High-risk CLL
Status: RECRUITING
Conditions: High Risk CLL|Chronic Lymphocytic Leukemia
Interventions: DRUG: VenObi+Ven or VenObi+VenZan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TIL Gean Therapy Combined With Immunotherapy for Advanced or Metastatic Refractory Breast Cancer
Status: RECRUITING
Conditions: Breast Cancer|Breast Carcinoma|Breast Cancer Metastatic|Breast Cancer Triple Negative
Interventions: BIOLOGICAL: Tumor Infiltrating Lymphocytes (TIL)|DRUG: Cyclophosphamid|DRUG: Fludarabine|DRUG: Interleukin-2|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Diagnostic Value of 3-T Magnetic Resonance Imaging (MRI) in Suspected Prostate Cancer
Status: COMPLETED
Conditions: Prostatic Neoplasms
Interventions: DEVICE: magnetic resonance imaging, Siemens
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of NOV-002 in Combination With Chemotherapy to Treat Lung Cancer
Status: COMPLETED
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: Paclitaxel|DRUG: NOV-002|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of Recombinant Adenovirus for Non Muscle Invasive Bladder Cancer
Status: TERMINATED
Conditions: Transitional Cell Carcinoma|Bladder Cancer|Carcinoma in Situ|Carcinoma in Situ Concurrent With Papillary Tumors
Interventions: BIOLOGICAL: CG0070 Adenovirus Vector|OTHER: Control Arm: Quadruple Choice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Talimogene Laherparepvec in Treating Patients With Recurrent Breast Cancer That Cannot Be Removed by Surgery
Status: TERMINATED
Conditions: Malignant Chest Wall Neoplasm|Recurrent Breast Carcinoma|Recurrent Inflammatory Breast Carcinoma|Stage IV Breast Cancer AJCC v6 and v7|Stage IV Inflammatory Breast Carcinoma
Interventions: OTHER: Laboratory Biomarker Analysis|BIOLOGICAL: Talimogene Laherparepvec
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Hydration to Prevent Contrast Induced Nephropathy in PCI for ST-elevation Myocardial Infarction.
Status: COMPLETED
Conditions: Contrast Induced Nephropathy
Interventions: DRUG: sodium chloride|DRUG: sodium chloride|DRUG: sodium bicarbonate|DRUG: sodium bicarbonate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Delta Neutrophil Index and Neutrophil Lymphocyte Ratio in Thyroid Malignancy
Status: COMPLETED
Conditions: Thyroid Cancer|Thyroid Nodule|Thyroid Diseases|Delta Neutrophyl Index|Immature Granulocyte Count|Neutrophyl to Lymphocyte Ratio
Interventions: DIAGNOSTIC_TEST: Complete Blood Count
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Yttrium-90 DOTA-TOC Intra-arterial (IA) Peptide Receptor Radionuclide Therapy (PRRT) for Neuroendocrine Tumor
Status: COMPLETED
Conditions: Neuroendocrine Tumor
Interventions: DRUG: 90Y-DOTA-TOC|DRUG: 68Ga-DOTA-TOC
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Engineered TILs/CAR-TILs to Treat Advanced Solid Tumors
Status: RECRUITING
Conditions: Liver Cancer|Lung Cancer|Breast Cancer|Colo-rectal Cancer|Brain Tumor|Solid Tumor, Adult|PD1|CTLA4
Interventions: BIOLOGICAL: TILs and CAR-TILs targeting HER2, Mesothelin, PSCA, MUC1, Lewis-Y, GPC3, AXL, EGFR, Claudin18.2/6, ROR1, GD1, or B7-H3
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Combined Fatty Acid Supplementation and Eccentric Exercise Training on Exercise Performance
Status: COMPLETED
Conditions: Exercise-induced Inflammation
Interventions: DIETARY_SUPPLEMENT: Fish Oil|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Open Label, Dose Escalating Study With Ertumaxomab In Patients With HER-2/Neu Expressing Advanced Solid Tumors
Status: TERMINATED
Conditions: Her2/Neu Positive Advanced Solid Tumors
Interventions: BIOLOGICAL: Ertumaxomab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Laparoscopic D2 Distal Gastrectomy Following Neoadjuvant Chemotherapy for Locally Advanced Gastric Cancers
Status: UNKNOWN
Conditions: Complications, Postoperative|Surgery--Complications|Cancer of Stomach|Chemotherapy Effect
Interventions: PROCEDURE: Laparoscopic D2 distal gastrectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Test - Retest Reproducibility of 18F Fluoroestradiol (FES) PET
Status: WITHDRAWN
Conditions: Breast Cancer
Interventions: DRUG: F-18 Fluoroestradiol|PROCEDURE: Computed Tomography|PROCEDURE: Positron Emission Tomography|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Safety, Tolerability, and Pharmacokinetics of SYHX1901 Tablets in Chinese Healthy Subjects
Status: UNKNOWN
Conditions: Healthy Subjects
Interventions: DRUG: SYHX 1901 tablets|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of a New Technology to Functional Recovery Upper Limb in Post Stroke Patients.
Status: UNKNOWN
Conditions: Stroke
Interventions: DEVICE: Armeo Spring|OTHER: Conventional Rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Postoperative Ascites After Somatostatin Infusion Following Hepatectomy for Hepatocellular Carcinoma
Status: COMPLETED
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: somatostatin infusion|DRUG: placebo infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Histocompatibility Leukocyte Antigen (HLA)-A*0201 Restricted Peptide Vaccine Therapy in Patients With Colorectal Cancer
Status: TERMINATED
Conditions: Colorectal Cancer|Colon Cancer|Rectal Cancer
Interventions: BIOLOGICAL: VEGFR1 and VEGFR2
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Beta-1 Adrenergic Inhibition to Reduce Cardiac Injury and Inflammation After Subarachnoid Hemorrhage (BADCATS)
Status: NOT_YET_RECRUITING
Conditions: Non-Traumatic Subarachnoid Hemorrhage
Interventions: DRUG: Metoprolol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Partnerships Between Schools and Public Mental Health Departments: Investigation of Multi-professional Interventions for Children Aged 3 to 8 With Mental Health Issues (Parpsych-Ed)
Status: UNKNOWN
Conditions: School Difficulties Associated With Mental Health Problems
Interventions: BEHAVIORAL: Questionnaires at the start and end of the school year
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Association of FcγRIIIA Polymorphism and THPO Expression With Response to Eltrombopag in Refractory ITP Patients
Status: UNKNOWN
Conditions: Immune Thrombocytopenic Purpura (ITP)
Interventions: DRUG: Eltrombopag
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intravesical Lactobacillus to Reduce Urinary Symptoms After Spinal Cord Injury
Status: RECRUITING
Conditions: Spinal Cord Injuries|Neurogenic Bladder
Interventions: DRUG: Culturelle 10 Billion CFU Capsule (2 doses)|DRUG: Culturelle 10 Billion CFU Capsule (4 doses)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Individualised Mapping in Persistent AF Ablation
Status: NOT_YET_RECRUITING
Conditions: Persistent Atrial Fibrillation
Interventions: PROCEDURE: Pulmonary veins isolation + Cartofinder-guided ablation|PROCEDURE: Pulmonary veins isolation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cohort Study of Patients With Hepatocellular Carcinoma and Circulating Tumor DNA Monitoring of Chemoembolization
Status: RECRUITING
Conditions: Circulating Tumor DNA|Hepatocellular Carcinoma Non-resectable|Transarterial Chemoembolization
Interventions: BIOLOGICAL: DNA
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Online Network Intervention to Increase HIV Pre-exposure Prophylaxis Intention
Status: COMPLETED
Conditions: Behavior, Health
Interventions: BEHAVIORAL: Mobile app information-only intervention|BEHAVIORAL: Mobile app social support network intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Safety and Effectiveness of Injections of Human Recombinant Interferon-gamma in Patients With AIDS Who Have Taken Zidovudine
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Zidovudine|DRUG: Interferon gamma-1b
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Amphinex Based Photochemical Internalisation (PCI) of Bleomycin in Patients With Cutaneous Cancer
Status: COMPLETED
Conditions: Head and Neck Neoplasms|Skin Neoplasms
Interventions: DRUG: Amphinex (TPCS2a)|DRUG: Bleomycin|OTHER: Illumination with CeramOptec laser
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nasal Packing as a Drug Delivery System Postoperatively in Chronic Sinusitis With Polyposis
Status: COMPLETED
Conditions: Chronic Sinusitis|Polyposis
Interventions: DRUG: pulmicort
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Antimicrobial Efficacy of Biogenic Gold Nano Particle From Pelargonium Graveolens Leaves Extract Mouthwash for Children
Status: RECRUITING
Conditions: Dental Caries|Gingivitis|Periodontitis
Interventions: DRUG: Gold Nano particle from Pelargonium Graveolens Mouthwash|DRUG: Chlorhexidine gluconate mouthwash .
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: MitraClip for the Treatment of Moderate Functional Mitral Regurgitation: EVOLVE-MR
Status: UNKNOWN
Conditions: Mitral Regurgitation|Heart Failure|Mitral Valve Regurgitation Due to Cardiomyopathy (Disorder)
Interventions: DEVICE: Transcatheter mitral valve repair|OTHER: Guideline-directed medical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of ADI-PEG 20 Versus Placebo in Subjects With NASH
Status: RECRUITING
Conditions: Nonalcoholic Steatohepatitis (NASH)
Interventions: DRUG: ADI-PEG20|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Neonatal Brain Ultrasound With CEUS and Elastography
Status: NOT_YET_RECRUITING
Conditions: Neonatal Hypoxic Ischemic Encephalopathy|Neonatal Stroke|Neonatal Encephalopathy, Unspecified
Interventions: DIAGNOSTIC_TEST: Brain contrast enhanced ultrasound, brain ultrasound elastography|DRUG: Sulfur Hexafluoride
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Incidence of Hypercapnea in Morbidly Obese Post-Surgical Bariatric Patients Using the Sen Tec Transcutaneous PCO2 Monitor
Status: COMPLETED
Conditions: Bariatric Patients
Interventions: DEVICE: Sentec monitoring device|DEVICE: sentec monitor
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: TransIent Perivascular Inflammation of the Carotid Artery (TIPIC) Syndrome: Clinical and Radiological Follow-up
Status: COMPLETED
Conditions: Cervical Pain|Vasculitis
Interventions: DIAGNOSTIC_TEST: Ultrasound exam with Doppler|BIOLOGICAL: Blood samples
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Staccato Prochlorperazine in Migraine (Out Patient)
Status: COMPLETED
Conditions: Migraine Headache|Aura
Interventions: DRUG: Inhaled Placebo|DRUG: Inhaled PCZ 5 mg|DRUG: Inhaled PCZ 7.5 mg|DRUG: Inhaled PCZ 10 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of PEMF for Patients With Knee OA
Status: RECRUITING
Conditions: Knee Osteoarthritis|Knee Pain Chronic
Interventions: DEVICE: Pulse Electromagnetic Field|DEVICE: Sham Pulse Electromagnetic Field
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Methotrexate in the Treatment of Axial Spondyloarthritis
Status: WITHDRAWN
Conditions: Spondylarthropathies|Spondylitis, Ankylosing
Interventions: DRUG: Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Study of LY3457263 in Healthy Participants and Participants With Type 2 Diabetes
Status: COMPLETED
Conditions: Healthy|Type 2 Diabetes
Interventions: DRUG: LY3457263|DRUG: Dulaglutide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Bortezomib With or Without Docetaxel in Treating Patients With Relapsed or Refractory Advanced Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DRUG: bortezomib|DRUG: docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Deep Brain Stimulation of Subthalamic Nucleus on the Hepatic Glucose Production in Parkinson's Disease
Status: TERMINATED
Conditions: Idiopathic Parkinson's Disease
Interventions: BEHAVIORAL: e.g., Protein and calorie controlled diet; Self-hypnotic relaxation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Carboplatin-Paclitaxel-Bevacizumab vs Carbo-Pacli-Beva-Rucaparib vs Carbo-Pacli-Ruca, Selected According to HRD Status, in Patients With Advanced Ovarian, Primary Peritoneal and Fallopian Tube Cancer, Preceded by a Phase I Dose Escalation Study on Ruca-Beva Combination
Status: RECRUITING
Conditions: Advanced (Stage IIIB-C-IV) Ovarian, Primary Peritoneal and Fallopian Tube Cancer
Interventions: DRUG: Carboplatin|DRUG: Paclitaxel|DRUG: Bevacizumab|DRUG: Rucaparib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HM242-Solution vs Comparator
Status: UNKNOWN
Conditions: Venous Leg Ulcer
Interventions: DEVICE: HM242-Solution|DEVICE: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Responsiveness to Acute Changes in Exercise and Relaxation (RACER) Trial
Status: COMPLETED
Conditions: Breast Cancer
Interventions: BEHAVIORAL: Aerobic Exercise and Relaxation|BEHAVIORAL: Aerobic Exercise Only|BEHAVIORAL: Relaxation Only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Positional Therapy Versus CPAP for Positional OSA
Status: COMPLETED
Conditions: Sleep Apnea Syndromes
Interventions: DEVICE: Night Shift positional device|DEVICE: continuous positive airway pressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Clopidogrel on Allergen Challenge in Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Clopidogrel|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Evaluate the Efficacy and Safety of Pioglitazone 15mg or 30mg Add-on in Patients With Type 2 Diabetes Mellitus Inadequately Controlled With Metformin and Dapagliflozin
Status: COMPLETED
Conditions: Type2 Diabetes
Interventions: DRUG: Metformin≥1000mg|DRUG: Pioglitazone 15mg|DRUG: Pioglitazone 30 mg|DRUG: Pioglitazone 15mg Placebo|DRUG: Pioglitazone 30mg Placebo|DRUG: Dapagliflozin 10mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Everolimus and Bortezomib in Treating Patients With Relapsed or Refractory Lymphoma
Status: TERMINATED
Conditions: 714leukemia|Lymphoma
Interventions: DRUG: Bortezomib|DRUG: Everolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Manage Diarrhea in Patients With Multiple Myeloma While Receiving Conditioning Chemotherapy for Autologous SCT
Status: TERMINATED
Conditions: Multiple Myeloma
Interventions: OTHER: Serum-derived bovine immunoglobulin/protein isolate (SBI)|DRUG: Colesevelam|OTHER: Double Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Magnesium Supplementation for Primary Prevention of Heart Failure in Obesity
Status: COMPLETED
Conditions: Obesity
Interventions: DIETARY_SUPPLEMENT: 400 mg of Magnesium Oxide twice daily for 24 weeks|OTHER: Open label (none)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION