pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Study to Evaluate the Safety of an Investigational Drug (Etoricoxib) in Patients With Osteoarthritis (OA) or Rheumatoid Arthritis (RA)(0663-066)
Status: COMPLETED
Conditions: Rheumatoid Arthritis,Osteoarthritis
Interventions: DRUG: MK0663, etoricoxib|DRUG: Comparator: Diclofenac sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Eltrombopag for Enhancing Platelet Engraftment in Adult Patients Undergoing Cord Blood Transplantation
Status: UNKNOWN
Conditions: Hematological Malignancy|Bone Marrow Failure Syndrome
Interventions: DRUG: Eltrombopag
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nexalin Therapy as a Viable Adjunctive Treatment for Substance Use Disorders
Status: ACTIVE_NOT_RECRUITING
Conditions: Depression|Anxiety|Insomnia|Substance Abuse
Interventions: DEVICE: TES Treatment|DEVICE: TES-SHAM Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Efficacy of Corticosteroid Injection and ESWT in Patients With CTS
Status: COMPLETED
Conditions: Carpal Tunnel Syndrome|Tenosynovitis
Interventions: DRUG: local injection|DEVICE: extracorporeal shock wave therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Remimazolam Versus Midaszolam for Sedation in Diagnostic Upper Gastrointestinal Endoscopy
Status: NOT_YET_RECRUITING
Conditions: Healthy
Interventions: DRUG: Remimazolam|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Prospective, Randomized, Multicenter Study of Comparison of TACE Combination With and Without EBRT for Hepatocellular Carcinoma With Portal Vein Tumor Thrombi
Status: UNKNOWN
Conditions: Carcinoma, Hepatocellular
Interventions: RADIATION: RT|PROCEDURE: TACE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Controlled Study Evaluating Cryocontact Therapy of Infantile Hemangiomas of Preterm Infants
Status: TERMINATED
Conditions: Hemangioma of Preterm Infants
Interventions: PROCEDURE: cryocontact therapy|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Iron and Vitamin D Supplementation to Iron Status in Iron Deficiency Anemia
Status: COMPLETED
Conditions: Iron Deficiency, Anaemia in Children
Interventions: DRUG: Elemental iron|DRUG: Elemental iron and Vit D
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Brexpiprazole Once-weekly (QW) Formulation in Patients With Acute Schizophrenia
Status: RECRUITING
Conditions: Acute Schizophrenia
Interventions: DRUG: OPC-34712FUM/ Brexpiprazole fumarate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Do Simple Running Technique Changes Reduce Pain and Change Injury Causing Mechanics
Status: COMPLETED
Conditions: Patellofemoral Pain Syndrome|Medial Tibial Stress Syndrome|Iliotibial Band Syndrome|Achilles Tendinopathy
Interventions: OTHER: Step rate increase
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tipifarnib in Treating Patients With Myelodysplastic Syndromes
Status: COMPLETED
Conditions: Chronic Myelomonocytic Leukemia|de Novo Myelodysplastic Syndromes|Previously Treated Myelodysplastic Syndromes|Refractory Anemia|Refractory Anemia With Excess Blasts|Refractory Anemia With Excess Blasts in Transformation|Refractory Anemia With Ringed Sideroblasts|Refractory Cytopenia With Multilineage Dysplasia
Interventions: DRUG: tipifarnib|OTHER: laboratory biomarker analysis|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aerosol Liposomal Cyclosporine for Chronic Rejection in Lung Transplant Recipients
Status: COMPLETED
Conditions: Disorder Related to Lung Transplantation|Bronchiolitis Obliterans|Decreased Immunologic Activity|Chronic Rejection of Lung Transplant
Interventions: DRUG: Liposomal aerosol cyclosporine|OTHER: standard immune suppression, oral
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Effectiveness Study of Intranasal Insulin Glulisine on Cognitive and Memory in Mild-Mod AD Patients.
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: Insulin glulisine|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Challenge Infection of Healthy Adult Volunteers With RSV A2
Status: COMPLETED
Conditions: Upper Respiratory Tract Infections
Interventions: BIOLOGICAL: 10^6.3 PFU of RSV A2|BIOLOGICAL: 10^7 PFU of RSV A2
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effect of Flixweed and Fig on Irritable Bowel Syndrome With Predominant Constipation: a Single Blind Randomized Clinical Trial.
Status: COMPLETED
Conditions: Irritable Bowel Syndrome Predominant Constipation
Interventions: OTHER: Descurainia Sophia|OTHER: Ficus carica
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: European, Multi-center, Exploratory Trial to Assess WEB Versus Other Endovascular Treatment in Ruptured Aneurysms.
Status: NOT_YET_RECRUITING
Conditions: Ruptured Aneurysm
Interventions: OTHER: Randomisation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lower Limb Blood Flow Geko vs Foot Pump
Status: COMPLETED
Conditions: Venous Thrombosis|Arthroplasty, Replacement, Hip
Interventions: DEVICE: Neuromuscular electrostimulation (NMES) device|DEVICE: Intermittent pneumatic compression (IPC) device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effects of Fructan Prebiotics on the Intestinal Microbiota
Status: COMPLETED
Conditions: Study Focus is to Define the Usual Gut Microbiota Following Prebiotic Feeding
Interventions: DIETARY_SUPPLEMENT: Prebiotic|DIETARY_SUPPLEMENT: Prebiotic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: TLIP Block and ESP Block For Perioperative Analgesia In Patients With Lumbar Spine Fusion Surgery
Status: COMPLETED
Conditions: Analgesia|Spine Fusion
Interventions: PROCEDURE: TLIP Block For Perioperative Analgesia In Patients With Lumbar Spine Fusion Surgery|PROCEDURE: ESP Block For Perioperative Analgesia In Patients With Lumbar Spine Fusion Surgery|PROCEDURE: Lidocaine injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Optimal Reperfusion Strategy for STEMI Patients With Anticipated PPCI Delay
Status: UNKNOWN
Conditions: ST Elevation Myocardial Infarction
Interventions: OTHER: Pharmacoinvasive strategy|OTHER: Reduced-dose facilitated PCI strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Different Rehabilitation Treatments After a Partial Removal of the Meniscus
Status: UNKNOWN
Conditions: Rehabilitation Post-meniscectomy
Interventions: PROCEDURE: Isotonic exercises|PROCEDURE: Isokinetic exercises|PROCEDURE: Isotonic and isokinetic exercises|PROCEDURE: ST
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Salvage Ovarian FANG™ Vaccine + Bevacizumab
Status: COMPLETED
Conditions: Stage III Ovarian Cancer|Stage IV Ovarian Cancer
Interventions: BIOLOGICAL: Vigil™ Vaccine|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Internet-based Coaching for Young Adults With Neuropsychiatric Disorders
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder|Autism Spectrum Disorder|Tourette's Disorder
Interventions: BEHAVIORAL: Habilitation (Internet-based support and coaching)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Tolerability of an Isobutylamido-thiazolyl-resorcinol Cream 0.2% for Facial Hyperpigmentation
Status: COMPLETED
Conditions: Facial Hyperpigmentation
Interventions: OTHER: Isobutylamido-thiazolyl-resorcinol Cream 0.2%|OTHER: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Clinical Impact of Pharmaceutical Consultations in Patients Treated for Chronic Obstructive Pulmonary Disease at Home
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: OTHER: Pharmaceutical consultation at the hospital|OTHER: Pharmaceutical consultation at the pharmacy|OTHER: Follow-up pharmaceutical consultation at the pharmacy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Atrial Fibrillation: Canadian Atrial Fibrillation Evaluation (CAFE) Study -
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DEVICE: Guidant Pulsar Max II or Insignia Plus DR|DEVICE: Atrial pacing preference turned on or off
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: PPROM Registry (Preterm Premature Rupture of Membranes)
Status: RECRUITING
Conditions: Fetal Membranes, Premature Rupture|Preterm Premature Rupture of the Membranes|Oligohydramnios|Premature Birth
Interventions: OTHER: There is no intervention associated with this study.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: DDI (Effect of Metformin and Furosemide on Rosuvastatin PK)
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Rosuvastatin|DRUG: Metformin HCl|DRUG: Furosemide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: AMD3100 Plus Pembrolizumab in Immune Checkpoint Blockade Refractory Head and Neck Squamous Cell Carcinoma
Status: WITHDRAWN
Conditions: Head and Neck Cancer
Interventions: DRUG: AMD3100|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Drug Drug Interaction Study Evaluating the Effect of Fluvoxamine or Fluconazole on PK and Safety of PF-04965842.
Status: COMPLETED
Conditions: Dermatitis, Atopic
Interventions: DRUG: Period 1 - Day 1: PF-04965842 administered|DRUG: Period 2: Cohort 1: Fluvoxamine & PF-04965842|DRUG: Period 2: Cohort 2: Fluconazole & PF-04965842
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Assessing Parenteral Antibiotics Versus Single-time Intra-operative Intra-dermal Antibiotic Administration for Prevention of SSI
Status: UNKNOWN
Conditions: Surgical Wound Infection|Surgical Site Infection
Interventions: DRUG: Ceftriaxone Sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination of Immunization and Radiotherapy for Malignant Gliomas (InSituVac1)
Status: UNKNOWN
Conditions: High Grade Glioma|Glioblastoma|Glioma of Brainstem|Glioma, Malignant
Interventions: COMBINATION_PRODUCT: Combined immune adjuvants and radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I Study of PH100 (Ecklonia Cava Phlorotannins)
Status: COMPLETED
Conditions: Safety Issues
Interventions: DRUG: Placebo|DRUG: PH100 100mg|DRUG: PH100 200mg|DRUG: PH100 400mg|DRUG: PH100 800mg|DRUG: PH100 1200mg|DRUG: PH100 1600mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: High-frequency nrTMS on the Contralateral Broca Mirror Area for Glioma Patients With Early Postoperative Aphasia
Status: NOT_YET_RECRUITING
Conditions: Non-fluent Aphasia|Glioma
Interventions: DEVICE: nrTMS treatment|DEVICE: nrTMS sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Measuring Rate of Anteriors Retraction With Two Different Techniques
Status: COMPLETED
Conditions: Class II Division 1 Malocclusion
Interventions: DEVICE: palatal and buccal retraction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility of Egg-Based Diet Interventions and Assessing Perinatal Mental Health
Status: RECRUITING
Conditions: Depression|Anxiety|Stress
Interventions: OTHER: Whole Liquid Egg|OTHER: Plant-based Egg Substitute
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Treatment Efficacy of Budesonide/Formoterol in Cough Variant Asthma and Typical Asthma Patients
Status: UNKNOWN
Conditions: Bronchial Asthma
Interventions: DRUG: budesonide 160μg/formoterol 4.5μg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dihydroartemisinin- Piperaquine Versus Artemether- Lumefantrine in the Treatment Uncomplicated Plasmodium Falciparum Malaria in Sudan
Status: UNKNOWN
Conditions: Malaria
Interventions: DRUG: Dihydroartemisinin- piperaquine|DRUG: artemether- lumefantrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial to Investigate Safety and Efficacy of SPM927 in Painful Diabetic Neuropathy
Status: COMPLETED
Conditions: Painful Diabetic Neuropathy
Interventions: DRUG: SPM927/Lacosamide|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Istalol™ 0.5% QD (Timolol Maleate/Sorbitol Complex, ISTA Pharmaceutical) to Brimonidine Tartrate 0.1% BID as Adjunctive Therapy to Latanoprost 0.005% in Adults With Ocular Hypertension (OHT) or Open-Angle Glaucoma (OAG)
Status: COMPLETED
Conditions: Ocular Hypertension|Open-Angle Glaucoma
Interventions: DRUG: Istalol and Optive|DRUG: Alphagan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Helicobacter Pylori, Atrophic Gastritis and Intestinal Metaplasia Registry and Prospective Study
Status: RECRUITING
Conditions: Helicobacter Pylori|Atrophic Gastritis|Intestinal Metaplasia
Interventions: DIAGNOSTIC_TEST: Esophagogastroduodenoscopy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Myelodysplastic Syndrome (MDS) Gastrointestinal (GI) Tolerability Study
Status: TERMINATED
Conditions: Myelodysplastic Syndrome|Transfusional Iron Overload
Interventions: DRUG: Deferasirox
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Smoking-cessation Interventions for Urban Hospital Patients
Status: COMPLETED
Conditions: Smoking Cessation
Interventions: BEHAVIORAL: Telephone Counseling|BEHAVIORAL: Fax-to-quit
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: CPX-351 or CLAG-M Regimen for the Treatment of Acute Myeloid Leukemia or Other High-Grade Myeloid Neoplasms in Medically Less-Fit Patients
Status: RECRUITING
Conditions: Acute Myeloid Leukemia|Myeloid Neoplasm
Interventions: DRUG: Liposome-encapsulated Daunorubicin-Cytarabine|DRUG: Cladribine|DRUG: Cytarabine|BIOLOGICAL: Recombinant Granulocyte Colony-Stimulating Factor|DRUG: Mitoxantrone|OTHER: Questionnaire Administration|OTHER: Quality-of-Life Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Maximum Tolerated Dose of Oral CB-03-10 With Dose Expansion Phase, in Advanced Solid Tumors
Status: RECRUITING
Conditions: Advanced Refractory Solid Tumors|Subjects Considered Likely to Respond to CB-03-10
Interventions: DRUG: CB-03-10
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Class I Medical Device on Post-surgical Scars
Status: COMPLETED
Conditions: Cicatrix|Post-Surgical Complication|Scar Itching|Keloid|Hypertrophic Scar
Interventions: DEVICE: Kaloidon Plus|DEVICE: silicone gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparison of Two Volar Plating Systems for Distal Radius Fractures
Status: COMPLETED
Conditions: Distal Radius Fracture
Interventions: PROCEDURE: Volar Plate Osteosynthesis Aptus 2.5|PROCEDURE: Volar Plate Osteosynthesis Inteos 2.5
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effects of Letrozole During the Luteal Phase After Controlled Ovarian Stimulation in Oocyte Donors.
Status: ACTIVE_NOT_RECRUITING
Conditions: Luteinised Follicular Cyst
Interventions: DRUG: Administration of letrozole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Filgrastim-Treated Donor Peripheral Stem Cell Transplantation in Treating Patients With Acute Leukemia</p>
Status: COMPLETED
Conditions: Leukemia
Interventions: DRUG: cyclophosphamide|DRUG: methotrexate|PROCEDURE: peripheral blood stem cell transplantation|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Iron Absorption From Iron Enriched Aspergillus Oryzae in Females Using Stable Isotope Methodology
Status: COMPLETED
Conditions: Iron Absorption
Interventions: DIETARY_SUPPLEMENT: Ferric pyrophosphate|DIETARY_SUPPLEMENT: Aspiron|DIETARY_SUPPLEMENT: Ferrous sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Fitness-adapted, Pembrolizumab-based Therapy for Untreated Classical Hodgkin Lymphoma Patients 60 Years of Age and Above
Status: RECRUITING
Conditions: Classical Hodgkin Lymphoma
Interventions: DRUG: Pembrolizumab|DRUG: Doxorubicin|DRUG: Vinblastine|DRUG: Dacarbazine|DRUG: Brentuximab vedotin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Exploratory Study of AVI-4020 in Patients With Possible Acute Neuroinvasive West Nile Virus (WNV) Disease
Status: TERMINATED
Conditions: West Nile Fever
Interventions: DRUG: AVI-4020 Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Physical Exercise and Jaques-Dalcroze Eurhythmics: Effects on Physical and Cognitive Functions, and Falls in Seniors
Status: COMPLETED
Conditions: Physical Function|Cognitive Function|Falls
Interventions: BEHAVIORAL: Jaques-Dalcroze eurhythmics training|BEHAVIORAL: Multicomponent exercise training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Tipranavir (TPV) and Ritonavir (RTV) on the Pharmacokinetic Characteristics of Tenofovir Disoproxil Fumarate in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Tipranavir low dose|DRUG: Tipranavir high dose|DRUG: Ritonavir low dose|DRUG: Ritonavir high dose|DRUG: Tenofovir disoproxil fumarate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Lu AA34893 in Patients With Bipolar Depression
Status: TERMINATED
Conditions: Depression in Patients With Bipolar Disorder
Interventions: DRUG: Lu AA34893|DRUG: Quetiapine fumarate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficiency of Neuromuscular Bite vs Physiotherapy in TMD Patients
Status: COMPLETED
Conditions: TMD
Interventions: DEVICE: Neuromuscular Bite (orthotic/sub-lingual)|PROCEDURE: Mandibular Physiotherapy|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study of Allogeneic Hematopoietic Stem Cell Transplant for Subjects With VEXAS (Vacuoles, E1 Enzyme, X-linked, Autoinflammatory, Somatic) Syndrome
Status: RECRUITING
Conditions: Immunodeficiency|Hematopoietic Stem Cell Transplantation
Interventions: PROCEDURE: Allogeneic HSCT|DRUG: Busulfan test dose|DRUG: Mycophenolate mofetil (MMF)|DRUG: Tacrolimus|DRUG: Busulfan|RADIATION: Total Body Irradiation (TBI)|DRUG: Fludarabine|DRUG: Cyclophosphamide (CY)|DRUG: Post-Transplant Cyclophosphamide (PTCY)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination of ATG-based Conditioning Regimen and PTCy for GVHD Prevention in Allo-HSCT After PD-1 Blockade
Status: NOT_YET_RECRUITING
Conditions: Graft-versus-host Disease|Hematological Malignancies
Interventions: DRUG: Cyclophosphamid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Dose Escalation Study of OMP-54F28 in Combination With Sorafenib in Patients With Hepatocellular Cancer
Status: COMPLETED
Conditions: Hepatocellular Cancer|Liver Cancer
Interventions: DRUG: OMP-54F28 with Sorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy Before Surgery in Treating Patients With Mesothelioma of the Lung
Status: COMPLETED
Conditions: Malignant Mesothelioma
Interventions: DRUG: cisplatin|DRUG: gemcitabine hydrochloride|PROCEDURE: conventional surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intervening With Opioid-Dependent MothersMothers and Infants
Status: RECRUITING
Conditions: Opioid Dependence|Parenting|Infant Development
Interventions: BEHAVIORAL: mABC|BEHAVIORAL: mDEF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Quantitative Assessment of Orofacial Muscle Function in FSHD
Status: RECRUITING
Conditions: Facioscapulohumeral Muscular Dystrophy
Interventions: PROCEDURE: Measurement of maximal expiratory pressures during forced static expiratory maneuvers sustained over 5 seconds
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effect of Qigong on the Symptom Clusters of Dyspnea, Fatigue, and Anxiety.
Status: COMPLETED
Conditions: Lung Cancer, Nonsmall Cell|Lung Cancer Non-Small Cell Stage 0|Lung Cancer, Nonsmall Cell, Stage I|Lung Cancer Non-Small Cell Stage II|Lung Cancer, Limited Stage Small Cell
Interventions: BEHAVIORAL: Qigong
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Neoadjuvant AXITINIB and AVELUMAB for Patients With Localized Clear-cell RCC
Status: RECRUITING
Conditions: Renal Cell Carcinoma
Interventions: DRUG: Axitinib|DRUG: Avelumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Interbody Fusion Devices in the Treatment of Cervicobrachial Syndrome
Status: COMPLETED
Conditions: Radiating Pain|Myelopathy|Cervicobrachial Syndrome
Interventions: DEVICE: Anterior cervical discectomy and fusion (ACDF) with PEEK Cage|DEVICE: Anterior cervical discectomy and fusion (ACDF) with a Valeo CSC Cage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Iadademstat With Hypomethylating Agent in Patients With Myelodysplastic Syndrome
Status: NOT_YET_RECRUITING
Conditions: Myelodysplastic Syndromes
Interventions: DRUG: Azacitidine Level -1|DRUG: Azacitidine Level 0|DRUG: Azacitidine Level 1|DRUG: Iadademstat Level -1|DRUG: Iadademstat Level 0|DRUG: Iadademstat Level 1
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Buprenorphine/Naloxone Continuation on Pain Control and Opioid Use
Status: UNKNOWN
Conditions: Opioid-use Disorder|Pain, Acute|Surgery
Interventions: DRUG: buprenorphine/naloxone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of a Vaginal Ring With Meloxicam in the Treatment of Dysmenorrhea
Status: COMPLETED
Conditions: Dysmenorrhea
Interventions: DRUG: Meloxicam|DRUG: Diclofenac Potassium|DRUG: Placebo Oral|DRUG: Placebo Vaginal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Drug-Drug Interaction Study of Voriconazole With Clarithromycin.
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Voriconazole 200 mg x 2 Tablets|DRUG: Clarithromycin 500 mg x 1Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study Evaluating the Safety of Elexacaftor/Tezacaftor/Ivacaftor in Participants With Cystic Fibrosis (CF)
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: ELX/TEZ/IVA|DRUG: IVA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: AllogeneiC Human Mesenchymal Stem Cells (hMSC) in Patients With Aging FRAilTy Via IntravenoUS Delivery
Status: COMPLETED
Conditions: Frailty
Interventions: BIOLOGICAL: Allogeneic Human Mesenchymal Stem Cells (allo-hMSCs)|BIOLOGICAL: Placebo|BIOLOGICAL: Penicillin/Streptomycin-Free Allogeneic Human Mesenchymal Stem Cells (allo-hMSCs)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Inpatient Cognitive-Behavioral Therapy to Reduce Suicide Risk Post-Discharge
Status: ACTIVE_NOT_RECRUITING
Conditions: Suicide, Attempted
Interventions: BEHAVIORAL: Cognitive Behavioral Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Intranasal Insulin Administration on Tissue Specific Insulin Sensitivity
Status: COMPLETED
Conditions: Insulin Resistance
Interventions: DRUG: Actrapid|DRUG: Placebo|RADIATION: [18F]-FDG PET-CT|DRUG: Hyperinsulinemic euglycemic clamp
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Utility of EUS-guided Microbiopsies in Pancreatic Cystic Lesions
Status: COMPLETED
Conditions: Pancreatic Cyst|IPMN|Mucinous Cyst|Pancreatic Adenocarcinoma
Interventions: DEVICE: EUS-guided microbiopsy|DIAGNOSTIC_TEST: Next Generation Sequencing
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Phase 3 Study of Surgery Combined With Neoadjuvant Chemotherapy(XELOX) in Colorectal Cancer With Resectable Liver Metastasis
Status: UNKNOWN
Conditions: Colorectal Cancer|Resectable Liver Metastasis
Interventions: DRUG: neoadjuvant chemotherapy with oxaliplatin and capecitabine|PROCEDURE: resection of liver metastasis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the RD-X19 Treatment Device in Individuals With Mild COVID-19
Status: COMPLETED
Conditions: COVID-19
Interventions: DEVICE: RD-X19|DEVICE: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MiDAS III (Mild® Decompression Alternative to Open Surgery): Vertos Mild Patient Evaluation Study
Status: COMPLETED
Conditions: Lumbar Spinal Stenosis
Interventions: PROCEDURE: Percutaneous Lumbar Decompression|DRUG: Epidural Steroid Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Buccal Screening Evaluation Using an RT-PCR Assay and a Rapid ELISA Test Among Symptomatic and Asymptomatic Patients
Status: UNKNOWN
Conditions: SARS-CoV-2|COVID-19
Interventions: DIAGNOSTIC_TEST: ELISA POCT vs RT-PCR
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effect Effect of Empagliflozin on Oxidative Stress in Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Empagliflozin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sulfasalazine in Preventing Acute Diarrhea in Patients With Cancer Who Are Undergoing Pelvic Radiation Therapy
Status: COMPLETED
Conditions: Diarrhea|Gastrointestinal Complications|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: sulfasalazine|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Role of Prophylactic Tranexamic Acid in Reducing Blood Loss During Elective Caesarean Section for Placenta Praevia Major
Status: UNKNOWN
Conditions: Hemorrhage From Placenta Previa, With Delivery
Interventions: DRUG: Tranexamic acid injection|DRUG: Normal Saline 0.9%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of Effectiveness of Home Based Sensory Interventions Along With Standard Therapy Versus Standard Therapy Alone in Autistic Children With Sensory Processing Abnormalities
Status: COMPLETED
Conditions: Autistic Children With Sensory Processing Abnormalities
Interventions: OTHER: Sensory interventions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Inflammation and Oxidative Stress of Adipose Tissue in Sleep Apnea Syndrome
Status: TERMINATED
Conditions: Decrease of Inflammation of Adipose Tissue|Sleep Apnea Syndrome
Interventions: DEVICE: cPAP|DEVICE: cPAP|DEVICE: cPAP|DEVICE: cPAP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Short-term Annatto Carotenoids Supplementation on Oxidative Stress Status in Healthy Individuals
Status: COMPLETED
Conditions: Oxidative Stress|Atherosclerosis
Interventions: DIETARY_SUPPLEMENT: Bixin|DIETARY_SUPPLEMENT: Norbixin|DIETARY_SUPPLEMENT: Lycopene|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of n-3 Fatty Acid Supplementation on Serum Levels, and Gene Expression of type2 Diabetes Patient
Status: UNKNOWN
Conditions: Diabetes Mellitus Type II
Interventions: DIETARY_SUPPLEMENT: n-3 Fatty Acid|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Amifostine in Treating Peripheral Neuropathy Caused by Paclitaxel in Patients With Solid Tumors
Status: COMPLETED
Conditions: Breast Cancer|Lung Cancer|Neurotoxicity|Ovarian Cancer|Prostate Cancer|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: Amifostine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of Volatile Anesthetics on Cerebral Oxygenation During Controlled Hypotension
Status: COMPLETED
Conditions: Oxygen Saturation
Interventions: DRUG: Sevoflurane|DRUG: Desflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of LM-108 as a Single Agent or in Combination With Toripalimab in Subjects With Advanced Solid Tumours
Status: RECRUITING
Conditions: Advanced Solid Tumor
Interventions: DRUG: LM-108|DRUG: Toripalimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Micro- and Macro-Circulation in Cardiac Surgery Patients
Status: NOT_YET_RECRUITING
Conditions: Cardiac Surgery|Coronary Artery Bypass Graft|Surgical Aortic Valve Replacement
Interventions: DIAGNOSTIC_TEST: Acquisition of cardiovascular signals and microcirculation sidestream darkfield images
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Transcutaneous Vagus Nerve Stimulation as a Complementary Therapy to Exercise in Chronic Fatigue
Status: NOT_YET_RECRUITING
Conditions: Chronic Fatigue Syndrome
Interventions: OTHER: APA program|OTHER: Active transcutaneous VNS|OTHER: Sham transcutaneous VNS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: A Clinical Study to Evaluate the Efficacy of a Stannous Fluoride Toothpaste for the Relief of Dentine Hypersensitivity in a Chinese Population
Status: COMPLETED
Conditions: Dentin Sensitivity
Interventions: DRUG: Sensodyne Sensitivity & Gum|DRUG: Crest Cavity Protection Fresh Lime|DRUG: Sensodyne Repair and Protect
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of a Food Preservative on Glucose Homeostasis
Status: COMPLETED
Conditions: Overweight
Interventions: OTHER: benzoate containing test drinks|OTHER: non sodium benzoate containing test drinks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Selenium Supplementation of Patients With Cirrhosis
Status: TERMINATED
Conditions: Liver Disease
Interventions: DIETARY_SUPPLEMENT: 200 µg selenium as selenate|DIETARY_SUPPLEMENT: 400 µg selenium as selenate|DIETARY_SUPPLEMENT: 200 µg selenium as selenomethionine|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Second Extension Study to Evaluate Safety and Tolerability of Influenza Vaccines in Adults and Elderly, and to Evaluate Immunogenicity and Concomitant Vaccination With Pneumococcal Vaccine in a Subgroup
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Cell culture derived seasonal trivalent influenza vaccine (cTIV)|BIOLOGICAL: Influenza virus vaccine (egg-derived seasonal trivalent, thiomersal free; eTIV_a).|BIOLOGICAL: cTIV or eTIV_a|BIOLOGICAL: cTIV+PV OR eTIV_a+PV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Comparing Buccal Infiltration and Inferior Alveolar Nerve Block for Extraction of Mandibular Teeth
Status: COMPLETED
Conditions: Buccal Infiltration Inferior Alveolar Nerve Block Articaine
Interventions: PROCEDURE: Buccal infiltration|PROCEDURE: Inferior alveolar nerve block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: An Open-Label, Phase I/II Study of Two Different Schedules of Dasatinib (Sprycel) and Decitabine (Dacogen) Used in Combination for Patients With Accelerated or Blastic Phase Chronic Myelogenous Leukemia (Protocol CA180357)
Status: TERMINATED
Conditions: Leukemia
Interventions: DRUG: Dasatinib|DRUG: Decitabine|DRUG: Decitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Short Term Pancreatic Stenting Registry
Status: COMPLETED
Conditions: Post-ERCP Acute Pancreatitis|Pancreatic Duct Stricture|Pancreatic Duct Stones|Pancreatic Duct Leakage
Interventions: DEVICE: The Advanix™ Pancreatic Stent and NaviFlex RX Pancreatic Delivery System and Pushers
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase II Dose-escalation Study to Assess the Feasibility and Safety of Transendocardial Delivery of Three Different Doses of Allogeneic Mesenchymal Precursor Cells (MPCs)in Subjects With Heart Failure
Status: COMPLETED
Conditions: Heart Failure
Interventions: BIOLOGICAL: Mesenchymal Precursor Cells (MPCs)|BIOLOGICAL: Mesenchymal Precursor Cells (MPCs)|BIOLOGICAL: Mesenchymal Precursor Cells (MPCs)|PROCEDURE: standard-of-care treatment with mock mapping and injection procedures.|PROCEDURE: standard-of-care treatment with mock mapping and injection procedures.|PROCEDURE: standard-of-care treatment with mock mapping and injection procedures.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Randomized Trial of PSMA PET Scan Before Definitive Radiation Therapy for Prostate Cancer
Status: TERMINATED
Conditions: Stage I Prostate Cancer American Joint Committee on Cancer (AJCC) v8|Stage II Prostate Cancer AJCC v8|Stage IIA Prostate Cancer AJCC v8|Stage IIB Prostate Cancer AJCC v8|Stage IIC Prostate Cancer AJCC v8|Stage III Prostate Cancer AJCC v8|Stage IIIA Prostate Cancer AJCC v8|Stage IIIB Prostate Cancer AJCC v8|Stage IIIC Prostate Cancer AJCC v8
Interventions: PROCEDURE: Computed Tomography|OTHER: Fluorine F 18 DCFPyL|PROCEDURE: Positron Emission Tomography|RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: ReSET Aim 1b: Restarting Safe Education and Testing for Children With Medical Complexity - COVID-19 Testing in School With Children and Staff
Status: COMPLETED
Conditions: Children With Medical Complexity (CMC)|COVID-19
Interventions: DIAGNOSTIC_TEST: BinaxNOW Rapid Antigen System
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Effect of Slanted Recession of Horizontal Muscle on Horizontal Strabismus With Abnormal Accommodative Convergence /Accommodation Ratio (AC/A)
Status: UNKNOWN
Conditions: Horizontal Strabismus With High AC/A Ratio
Interventions: PROCEDURE: conducting the slanted recession technique on the superior and inferior poles|PROCEDURE: conducting the augmented recession technique on the muscle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of a Novel Dietary Ingredient on Hair Growth and Skin's Appearance
Status: RECRUITING
Conditions: Hair Thinning|Facial Skin Texture|Skin Ageing
Interventions: DIETARY_SUPPLEMENT: Biotin and silicon|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Lymphodepletion With ALLO-647 in Adults With R/R Large B Cell Lymphoma Receiving ALLO-501A Allogeneic CAR T Cell Therapy
Status: ACTIVE_NOT_RECRUITING
Conditions: Relapsed/Refractory Large B Cell Lymphoma
Interventions: BIOLOGICAL: ALLO-647|DRUG: Fludarabine|DRUG: Cyclophosphamide|GENETIC: ALLO-501A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of IPH4102 in Patients With Relapsed/Refractory Cutaneous T-cell Lymphomas (CTCL)
Status: COMPLETED
Conditions: Cutaneous T-Cell Lymphoma
Interventions: BIOLOGICAL: IPH4102
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of WBV on Muscle Stiffness and Reflex Activity in Stroke.
Status: COMPLETED
Conditions: Stroke
Interventions: DEVICE: paretic leg-control|DEVICE: paretic leg-WBV|DEVICE: non-paretic leg-control|DEVICE: non-paretic leg-WBV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Enfortumab Vedotin Alone or With Other Therapies for Treatment of Urothelial Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Carcinoma, Transitional Cell|Urinary Bladder Neoplasms|Urologic Neoplasms|Renal Pelvis Neoplasms|Urothelial Cancer|Ureteral Neoplasms|Urethral Neoplasms
Interventions: DRUG: enfortumab vedotin (EV)|DRUG: pembrolizumab|DRUG: cisplatin|DRUG: carboplatin|DRUG: gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Breast Lesions Characterization on Contrast Enhanced Ultrasound With Histopathological Correlation
Status: UNKNOWN
Conditions: Malignant Neoplasm, Overlapping Lesion of Breast
Interventions: DRUG: Sonovue, Bracco
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Miss Rate of Gastric Neoplasms Under Computer-aided Endoscopy
Status: NOT_YET_RECRUITING
Conditions: Gastric Neoplasm|Artificial Intelligence
Interventions: DEVICE: AI-assisted upper gastrointestinal endoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Cranioplasty On Cerebral Perfusion
Status: COMPLETED
Conditions: Head Injuries|Subarachnoid Haemorrhage|Intra-cerebral Haemorrhage|Cerebral Thrombosis|Infarction, Middle Cerebral Artery
Interventions: PROCEDURE: Cerebral perfusion evaluation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Rituximab for the Otolaryngologic Manifestations of Granulomatosis With Polyangiitis
Status: TERMINATED
Conditions: Granulomatosis With Polyangiitis (Wegener's Granulomatosis)
Interventions: DRUG: Rituximab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: RCT of Adjunctive Curcumin and the Meru Health Program
Status: COMPLETED
Conditions: Depression
Interventions: BEHAVIORAL: Meru Health Program|DIETARY_SUPPLEMENT: Curcumin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Do Laryngeal Tissue Changes in Patients Suspected of Having Laryngopharyngeal Reflux Predict Response to Treatment?
Status: COMPLETED
Conditions: Larynx Disease|Gastroesophageal Reflux
Interventions: DRUG: Prevacid|PROCEDURE: Esophageal and Laryngeal Biopsies
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Contrast Enhanced Ultrasound Evaluation of Brain Perfusion in Neonatal Post-Hemorrhagic Hydrocephalus
Status: WITHDRAWN
Conditions: Neonatal Post-Hemorrhagic Hydrocephalus
Interventions: DRUG: Sulfur Hexafluoride Lipid Type A Microspheres 25 MG Intravenous Powder for Suspension [LUMASON]
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC