pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Effectiveness and Safety of Topical Ranibizumab for Treatment of Corneal Neovascularization (NV)
Status: COMPLETED
Conditions: Corneal Neovascularization
Interventions: DRUG: Ranibizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase III Trial of Topical Formulation of Sirolimus to Skin Lesions in Patients With Tuberous Sclerosis Complex (TSC)
Status: COMPLETED
Conditions: Tuberous Sclerosis|Angiofibroma|Hypomelanotic Macule|Plaque
Interventions: DRUG: NPC-12G gel|DRUG: Placebo gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Community Partners in Care is a Research Project Funded by the National Institutes of Health
Status: COMPLETED
Conditions: Depression|Information Dissemination|Social Determinants of Health
Interventions: OTHER: Quality Improvement Program|BEHAVIORAL: Resources for Services Expert Team|BEHAVIORAL: Community Engagement and Planning Council
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Vestibular Stimulation, Exercise and Light Optimization for Circadian Clock Enhancement (Velocce)
Status: UNKNOWN
Conditions: Healthy Aging
Interventions: BEHAVIORAL: Adapted Physical Activity (APA)|BEHAVIORAL: Bright Light Exposure (BLE)|BEHAVIORAL: Galvanic Vestibular Stimulation (GVS)|BEHAVIORAL: Health Education program (HE)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Problem Solving Therapy and Antidepressant Therapy on Cerebral Perfusion and Brain Derived Neurotropic Factor (BDNF) in Depressed Elders
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: BEHAVIORAL: problem solving therapy|DRUG: Sertraline
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety, Pharmacokinetics and Pharmacodynamics Study of GNR-086 and Ilaris® in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: BIOLOGICAL: GNR-086|BIOLOGICAL: Ilaris®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Registry for Invasive and Non-invasive Anatomical Assessment and Outcome of Coronary Artery Anomalies
Status: RECRUITING
Conditions: Anomalous Coronary Artery Origin|Anomalous Coronary Artery Course|Anomalous Coronary Artery With Aortic Origin and Course Between the Great Arteries
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Improving Negative Symptoms & Community Engagement in Veterans With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia|Serious Mental Illness
Interventions: BEHAVIORAL: Engaging in Community Roles and Experiences (ENCoRE)|BEHAVIORAL: Health & Wellness (H&W)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Short-term Outcomes of Full Bowel Preparation (MBP+OA) for Rectal Resections for Cancer Versus MBP Alone
Status: RECRUITING
Conditions: Rectal Cancer
Interventions: PROCEDURE: Full bowel preparation|PROCEDURE: Mechanical bowel preparation only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Intradiscal Injection of Viable Placental Tissue Extract in Subjects With One or Two Level, Symptomatic Lumbar Intervertebral Disc Degeneration
Status: UNKNOWN
Conditions: Degenerative Disc Disease|Pain
Interventions: DRUG: Injectable placental tissue extract called BioDGenesis (Active Product)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility of Endovascular Repair Of Ascending Aortic Pathologies
Status: RECRUITING
Conditions: Aortic Dissection|Intramural Hematoma|Penetrating Ulcer|Pseudoaneurysm
Interventions: DEVICE: Endovascular repair with Valiant PS-IDE Stent Graft
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cough According to Stimulus Type in PD
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DRUG: Capsaicin vapor|OTHER: fog|RADIATION: Videofluoroscopic swallow evaluation|DEVICE: Nebulizer
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: To Evaluate Effects of GSK2256294 on Pulmonary Artery Pressure in Healthy Volunteers Under Normoxic and Hypoxic Conditions
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: GSK2256294|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety, Pharmacokinetics and Pharmacodynamics of MK-8325 in Hepatitis C-Infected Males (MK-8325-002)
Status: TERMINATED
Conditions: Hepatitis C, Chronic
Interventions: DRUG: MK-8325|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Ranibizumab (Intravitreal Injections) in Patients With Visual Impairment Due to Diabetic Macular Edema
Status: COMPLETED
Conditions: Diabetic Macular Edema
Interventions: DRUG: Ranibizumab|PROCEDURE: Laser photocoagulation|DRUG: Sham ranibizumab|PROCEDURE: Sham laser photocoagulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: RT001 in Amyotrophic Lateral Sclerosis
Status: UNKNOWN
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DRUG: RT001|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Early Progressive Strength Exercise for Treatment of Acute Achilles Tendon Rupture.
Status: COMPLETED
Conditions: Achilles Tendon Rupture
Interventions: OTHER: Standard exercises|OTHER: Standard exercises plus Early progressive exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Activity of Eculizumab for Prevention of Delayed Graft Function In Deceased Donor Kidney Transplant
Status: TERMINATED
Conditions: Delayed Function of Renal Transplant
Interventions: DRUG: Eculizumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Sweetheart Study: Oral Glucose for Reducing Stress During Echocardiographic Assessment in Infants in the NICU
Status: COMPLETED
Conditions: Cardiac Echocardiography Assessment
Interventions: DRUG: Glucose 25% oral solution|OTHER: Oral water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sonograms Enable Looking Forward - Home Examinations Led by Providers Validation Study
Status: COMPLETED
Conditions: Fertility Risk
Interventions: DEVICE: Transvaginal ultrasound performed by a woman herself (with HCP supervision via telemedicine)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Study of the Efficacy and Safety of MEDI-546 in Systemic Lupus Erythematosus
Status: COMPLETED
Conditions: Systemic Lupus Erythematosus
Interventions: BIOLOGICAL: Anifrolumab 300 mg|BIOLOGICAL: Anifrolumab 1000 mg|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial to Determine the Effects of Bardoxolone Methyl on eGFR in Patients With Type 2 Diabetes and Chronic Kidney Disease
Status: COMPLETED
Conditions: Chronic Kidney Disease|Type 2 Diabetes|Diabetic Nephropathy
Interventions: OTHER: Placebo|DRUG: Bardoxolone Methyl (RTA 402)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Repurposing Colchicine to Improve Vascular Function in Hypertension
Status: COMPLETED
Conditions: Essential Hypertension
Interventions: DRUG: Colchicine Tablets|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Dexpanthenol Mouthwash to Treat Oral Mucositis
Status: UNKNOWN
Conditions: Oral Mucositis (Ulcerative) Due to Radiation
Interventions: DRUG: Dexpanthenol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: ANGIOCOMB Antiangiogenic Therapy for Pediatric Patients With Diffuse Brain Stem and Thalamic Tumors
Status: COMPLETED
Conditions: Brainstem Glioma
Interventions: DRUG: Thalidomide, etoposide, celecoxib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radial-Probe Endobronchial Ultrasound in Detecting Atelectasis in Patients Undergoing Peripheral Bronchoscopy
Status: COMPLETED
Conditions: Malignant Neoplasms of Respiratory and Intrathoracic Organs|Lung Neoplasm
Interventions: PROCEDURE: Bronchoscopy|PROCEDURE: Radial Probe Endobronchial Ultrasound
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Adjunctive Mood Management for Telephone-based Smoking Cessation
Status: COMPLETED
Conditions: Nicotine Dependence
Interventions: BEHAVIORAL: Behavioral mood management|OTHER: Health education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Music Therapy and Hematopoietic Stem Cell Transplant
Status: COMPLETED
Conditions: Hematopoietic Stem Cell Transplant
Interventions: BEHAVIORAL: Music Therapy|BEHAVIORAL: No Music Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: BAY 56-3722 in Treating Patients With Recurrent, Unresectable, or Metastatic Kidney Cancer
Status: WITHDRAWN
Conditions: Stage IV Renal Cell Cancer|Recurrent Renal Cell Cancer
Interventions: DRUG: BAY 56-3722|PROCEDURE: enzyme inhibitor therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Temelimab as a Disease Modifying Therapy in Patients With Neuropsychiatric Symptoms in Post-COVID 19 or PASC Syndrome
Status: COMPLETED
Conditions: Post-COVID-19 Syndrome
Interventions: DRUG: Temelimab 54mg/kg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Homocysteine-Lowering Therapy With Folic Acid, Vitamin B12, and Vitamin B6 on Endothelium-Dependent Vasodilatation of Forearm Resistance Vessels in Patients With Coronary Heart Disease
Status: COMPLETED
Conditions: Cardiovascular Disease|Endothelial Dysfunction
Interventions: DRUG: folic acid, vitamin B12 and B6 and rosuvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Mantle Cell Lymphoma at Diagnosis for Patients Under 65 Years
Status: COMPLETED
Conditions: Mantle Cell Lymphoma
Interventions: DRUG: Adriblastin|DRUG: dexamethasone|DRUG: Chlorambucil|DRUG: rituximab|DRUG: cyclophosphamide|DRUG: alkeran|PROCEDURE: Total body irradiation (8Gy/4fr)|DRUG: vincristine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of Safety and Efficacy for the NEUROMARK System in Subjects With Chronic Rhinitis (PARAGON)
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Rhinitis
Interventions: DEVICE: NEUROMARK System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Once Daily In-situ Forming Versus Twice-daily Conventional Metronidazole Vaginal Gels for Treatment of Bacterial Vaginosis
Status: COMPLETED
Conditions: Vaginitis
Interventions: DRUG: MTZ vaginal gel|DRUG: Conventional MTZ vaginal gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Juvederm Ultra With Lidocaine Compared With Restylane for the Correction of Nasolabial Folds
Status: COMPLETED
Conditions: Nasolabial Folds
Interventions: DEVICE: Hyaluronic acid gel (24 mg/mL) with 0.3% lidocaine|DEVICE: A gel of hyaluronic acid (concentration of 20 mg/mL)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Influenza A H3N2 Human Challenge Study in Healthy Adult Volunteers
Status: COMPLETED
Conditions: Determine Minimally to Moderately Infective Dose (MMID) of Influenza A H3N2
Interventions: OTHER: Live recombinantly derived A/Bethesda/MM1/H3N2 virus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Cohorts of Docetaxel or Cabazitaxel in Combination With the Potent CYP3A4 Inhibitor, Clarithromycin
Status: TERMINATED
Conditions: Prostate Cancer
Interventions: DRUG: Docetaxel|DRUG: Cabazitaxel|DRUG: Clarithromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tobacco Treatment in the Context of Lung Cancer Screening
Status: COMPLETED
Conditions: Smoking Cessation
Interventions: BEHAVIORAL: Text messaging plus nicotine replacement therapy|OTHER: Standard Care at Lung Cancer Screening
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Quadratus Lumborum Block by Paraspinous Sagittal Shift Approach With Different Concentrations Of Bupivacaine in Hip Surgeries
Status: UNKNOWN
Conditions: Hip Surgeries
Interventions: OTHER: quadratus lumborum block by paraspinous sagittal shift approach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Biomarkers in Patients With Previously Untreated Invasive Ovarian Epithelial, Fallopian Tube, or Primary Peritoneal Cancer
Status: COMPLETED
Conditions: Fallopian Tube Carcinoma|Ovarian Carcinoma|Primary Peritoneal Carcinoma
Interventions: OTHER: Laboratory Biomarker Analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: SHR2554 Clinical Study of Chidamide in the Treatment of T-cell Lymphoma
Status: RECRUITING
Conditions: Relapsed/Refractory PTCLT With at Least One Line of Prior Systemic Therapy
Interventions: DRUG: SHR2554; Chidamide analog tablets|DRUG: SHR2554 analog tablets; Chidamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Injectable Association of Dexamethasone, Dipyrone and Hydrocobalamin in Lumbar Sciatic Pain
Status: COMPLETED
Conditions: Lumbar Sciatic Pain
Interventions: DRUG: Dextralgen|DRUG: Meloxicam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Beneficial Effects of Antenatal Magnesium Sulfate (BEAM Trial)
Status: COMPLETED
Conditions: Cerebral Palsy|Intraventricular Hemorrhage|Periventricular Leukomalacia|Pulmonary Edema|Abruptio Placentae
Interventions: DRUG: magnesium sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Trial Investigating NN1218 in Subjects With Type 1 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 1
Interventions: DRUG: NN1218|DRUG: insulin aspart|DRUG: NN1218|DRUG: NN1218|DRUG: NN1218|DRUG: NN1218
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Early Effects of Abaloparatide on Tissue-Based Indices of Bone Formation and Resorption
Status: COMPLETED
Conditions: Osteoporosis, Postmenopausal|Osteoporosis|Osteoporosis Vertebral|Osteoporosis Risk|Osteoporosis Fracture|Osteoporosis Localized to Spine|Osteoporosis, Age-Related|Osteoporosis Senile|Osteoporosis of Vertebrae
Interventions: DRUG: Abaloparatide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Muscle Energy Technique Versus Myofacial Release in Adolescents With Spinal Deformity
Status: COMPLETED
Conditions: Idiopathic Spinal Deformities
Interventions: OTHER: muscle energy technique and myofacial release (physiotherapy techniques)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial for Assessment of Anti-SARS-CoV-2 Serum for Early Treatment of COVID-19 Cases
Status: UNKNOWN
Conditions: Immunosuppression|Cancer|COVID-19|Other Complication of Kidney Transplant|Chemotherapy|Renal Disease|Diabetes Mellitus|Cardiovascular Diseases|Chronic Obstructive Pulmonary Disease
Interventions: BIOLOGICAL: AntiSARS-CoV-2 Serum|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Combination of Platelet-Rich Fibrin and Calcium Sulfate in Socket Augmentation
Status: COMPLETED
Conditions: Tooth Extraction
Interventions: COMBINATION_PRODUCT: platelet-rich fibrin and calcium sulfate|COMBINATION_PRODUCT: platelet-rich fibrin and xenograft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Ultrasound Evaluation and Vestibular Perception Thresholds Changes in Women Affected by Vestibulodynia (VBD) After One Cycle of Pixel CO2-Alma Fractionated Laser
Status: UNKNOWN
Conditions: Vestibulodynia (VBD) From at Least 6 Months
Interventions: DEVICE: Fractionated Laser (Pixel CO2-Alma)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PulseHaler Drug Deposition Study in Chronic Obstructive Pulmonary Disease Patients
Status: COMPLETED
Conditions: COPD
Interventions: DEVICE: Pulsehaler|DRUG: Nebulizer & Albuterol 0.5ml
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Symptoms and Consequences of Coloanal Continuity Reconstruction
Status: ACTIVE_NOT_RECRUITING
Conditions: Rectal Cancer
Interventions: PROCEDURE: Pre- and post-operative consultation|PROCEDURE: Stomatherapy consultation|PROCEDURE: Questionnaires
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Exploring the Effects of Coenzyme Q10 on Bioenergetics Metabolism in Geriatric Bipolar Depression
Status: COMPLETED
Conditions: Bipolar Depression
Interventions: DRUG: Coenzyme Q10
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Electroacupuncture on Obesity
Status: RECRUITING
Conditions: Obesity
Interventions: OTHER: Electroacupuncture|OTHER: Sham acupuncture|OTHER: Health education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dual mTorc Inhibition in advanCed/Recurrent Epithelial Ovarian, Fallopian Tube or Primary Peritoneal Cancer (of Clear Cell, Endometrioid and High Grade Serous Type, and Carcinosarcoma)
Status: UNKNOWN
Conditions: Ovarian Cancer|Ovarian Neoplasms|Ovarian Carcinosarcoma|Ovarian Serous Adenocarcinoma|Ovarian Endometrioid Adenocarcinoma|Ovarian Clear Cell Adenocarcinoma|Fallopian Tube Cancer|Fallopian Tube Neoplasms|Primary Peritoneal Carcinoma|Primary Peritoneal Serous Adenocarcinoma
Interventions: DRUG: Paclitaxel|DRUG: TAK228
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: "Outcomes of Tracheostomy Done for Patients Admitted in Anesthesia Intensive Care Units of Assiut University Hospital"
Status: COMPLETED
Conditions: Tracheostomy Complication
Interventions: DEVICE: Tracheostomy tube
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Safety and Effectiveness of Oral Levofloxacin Compared With Oral Ciprofloxacin in the Treatment of Complicated Urinary Tract Infections
Status: COMPLETED
Conditions: Urinary Tract Infections|Bacteriuria|Urologic Diseases|Pyelonephritis|Neurogenic Bladder
Interventions: DRUG: Levofloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Comparative Study for the Optimal Treatment Method of Lateral Epicondylosis
Status: COMPLETED
Conditions: Tennis Elbow
Interventions: PROCEDURE: physiotherapy|PROCEDURE: extracorporeal shockwave therapy|PROCEDURE: prolotherapy|PROCEDURE: platelet-rich plasma
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Dexmedetomidine in Preventing Cough and Postoperative Pain After Laryngeal Surgery for Cancer
Status: UNKNOWN
Conditions: Laryngectomy; Status
Interventions: DRUG: Dexmedetomidine Injectable Product|DRUG: Midazolam injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pharmacokinetics and Efficacy of Multiple Dosing of LP-98 for Injection in HIV-infected Patients
Status: NOT_YET_RECRUITING
Conditions: Hiv
Interventions: DRUG: Subjects will be randomly assigned to receive 1.25 mg, 2.5 mg, 5 mg, or 10 mg of LP-98.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Early Vitamin D3 Supplementation for Critically Ill Patients
Status: RECRUITING
Conditions: Vitamin D Deficiency|Critical Illness
Interventions: DIETARY_SUPPLEMENT: Vitamin D3|DIETARY_SUPPLEMENT: Medium Chain Triglycerides (MCT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of GSK Biological's Candidate Tuberculosis Vaccine Mtb72F/AS02 in Healthy PPD-negative Adults.
Status: COMPLETED
Conditions: Tuberculosis (TB)
Interventions: BIOLOGICAL: Mtb72F/AS02.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Antioxidants and Pulmonary Rehabilitation in COPD Patients
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease|COPD
Interventions: DIETARY_SUPPLEMENT: Antioxidant Supplementation associated to Comprehensive respiratory Rehabilitation Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study Evaluating Pyrotinib/Pyrotinib in Combination With Docetaxel in Patients With HER2+ Advanced Gastric Cancer
Status: UNKNOWN
Conditions: HER2 Positive Gastric Cancer
Interventions: DRUG: Pyrotinib/Pyrotinib with Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: COVID-19 MP Biomedicals Rapid SARS-CoV-2 Antigen Test Usability
Status: COMPLETED
Conditions: Sars-CoV-2 Infection|COVID-19
Interventions: DEVICE: Rapid SARS-CoV-2 Antigen Test
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Phase III Study Comparing Zegerid® With Losec® for the Relief of Heartburn Associated With Gastroesophageal Reflux Disease
Status: COMPLETED
Conditions: Gastroesophageal Reflux
Interventions: DRUG: Zegerid|DRUG: Losec
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: EndoCuff-assisted Versus Standard Colonoscopy for Adenoma Detection
Status: COMPLETED
Conditions: Polyp|Adenoma|Cancer
Interventions: DEVICE: EndoCuff-assisted colonoscopy|DEVICE: Standard colonoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of Durvalumab With or Without Tremelimumab in Endometrial Cancer
Status: COMPLETED
Conditions: Endometrial Cancer|Endometrial Carcinosarcoma|Endometrial Carcinoma|Endometrial Cancer Recurrent|Endometrial Carcinoma, Recurrent
Interventions: DRUG: Durvalumab|DRUG: Tremelimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Fish Oils on Blood Pressure, Heart Rate Variability and Liver Fat in the Polycystic Ovary Syndrome
Status: COMPLETED
Conditions: Polycystic Ovary Syndrome
Interventions: DIETARY_SUPPLEMENT: Ocean Nutrition 2050|DIETARY_SUPPLEMENT: Olive oil capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SatCare: Remote Support for Ambulance Clinicians in Medical Emergencies
Status: COMPLETED
Conditions: Emergency Medical Services|Emergency Service, Hospital
Interventions: DIAGNOSTIC_TEST: Enhanced communications & ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Changes in Patient Reported Constipation Among Advanced Cancer Patients After Receiving an Educational Intervention
Status: COMPLETED
Conditions: Advanced Cancers
Interventions: BEHAVIORAL: Questionnaires|BEHAVIORAL: Video|BEHAVIORAL: Fact Sheet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Ipilimumab and Decitabine in Treating Patients With Relapsed or Refractory Myelodysplastic Syndrome or Acute Myeloid Leukemia
Status: ACTIVE_NOT_RECRUITING
Conditions: Previously Treated Myelodysplastic Syndrome|Recurrent Acute Myeloid Leukemia|Recurrent Acute Myeloid Leukemia, Myelodysplasia-Related|Recurrent Myelodysplastic Syndrome|Refractory Acute Myeloid Leukemia|Refractory Myelodysplastic Syndrome|Secondary Acute Myeloid Leukemia|Secondary Myelodysplastic Syndrome
Interventions: DRUG: Decitabine|BIOLOGICAL: Ipilimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination of Ultrasound Treatment and Neck Liposuction for Skin Tightening
Status: WITHDRAWN
Conditions: Skin Laxity
Interventions: PROCEDURE: Neck Liposuction and Ultrasound Treatment|PROCEDURE: Sham Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dose Response of Pursed Lip Breathing With Diaphragmatic Breathing On Pulmonary Functions in Patients With COPD
Status: COMPLETED
Conditions: COPD
Interventions: OTHER: Pursed Lip Breathing|OTHER: Pursed Lip Breathing +DB|OTHER: Conservative care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of miRNA Expression Pattern as Diagnostic and Prognostic Biomarker in Amyotrophic Lateral Sclerosis
Status: TERMINATED
Conditions: Amyotrophic Lateral Sclerosis|ALS
Interventions: OTHER: Clinical evaluation|PROCEDURE: Muscular biopsy|PROCEDURE: Lumbar puncture|PROCEDURE: Blood sampling|OTHER: Neurological assessments|PROCEDURE: Neuro-muscular biopsy and lumbar puncture|PROCEDURE: Muscular biopsy|PROCEDURE: Blood sample|DEVICE: Cervical spinal cord and brain MRI
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Understanding the Effects of Water-related Appetite Expectancies on Caloric Intake in College Students
Status: WITHDRAWN
Conditions: Appetitive Behavior|Weight Loss|Water|Energy Intake
Interventions: BEHAVIORAL: Expectancy and Water|BEHAVIORAL: No Expectancy and Water|BEHAVIORAL: No Water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RCT to Evaluate Social Skills in Children With Autism Using VR Technology (SoCaVR)
Status: RECRUITING
Conditions: Autism Spectrum Disorder|Social Communication
Interventions: DEVICE: Floreo VR|DEVICE: VR Control|DEVICE: VR Control Crossover
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect Of Preoperative Parameters On Success After DMEK Surgery
Status: COMPLETED
Conditions: Fuchs' Endothelial Dystrophy|Pseudophakic Bullous Keratopathy|Descemet's Membrane; Defect|Herpetic Keratitis|Angle's Classification|Endothelial Dysfunction
Interventions: PROCEDURE: Descemet membrane endothelial keratoplasty (DMEK)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Accuracy& Orbital Volume Using Patient Specific Titanium Implant Vs Zirconia for Orbital Floor Reconstruction
Status: RECRUITING
Conditions: Blow-Out Fractures|Orbital Fractures|Orbital Floor Fracture|Orbital Trauma
Interventions: PROCEDURE: Orbital floor reconstruction with Patient Specific Zirconia Implant|PROCEDURE: Orbital floor reconstruction with Patient Specific Titanium Implant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Deep TMS of Neural Circuits Associated With Stimulant Use Disorder
Status: NOT_YET_RECRUITING
Conditions: Methamphetamine Use Disorder|Transcranial Magnetic Stimulation
Interventions: DEVICE: Deep Transcranial Magnetic Stimulation (dTMS) H4 coil - Active|DEVICE: Deep Transcranial Magnetic Stimulation (dTMS) H4 coil - Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Preemie Hypothermia for Neonatal Encephalopathy
Status: COMPLETED
Conditions: Infant, Newborn|Hypoxia, Brain|Hypoxia-Ischemia, Brain|Encephalopathy, Hypoxic-Ischemic|Hypoxic-Ischemic Encephalopathy|Ischemic-Hypoxic Encephalopathy
Interventions: DEVICE: Hypothermia|PROCEDURE: Normothermic Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bortezomib (Velcade) in Waldenstrom's Macroglobulinemia
Status: COMPLETED
Conditions: Waldenstrom's Macroglobulinemia|Lymphoplasmacytic Lymphoma
Interventions: DRUG: Bortezomib (Velcade)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Efficacy and Safety of Ziprasidone in Patients With Acute Exacerbation of Schizophrenia or Schizoaffective Disorder
Status: TERMINATED
Conditions: Schizophrenia|Schizoaffective Disorder
Interventions: DRUG: Ziprasidone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of AV-1959, an Amyloid Beta Vaccine
Status: RECRUITING
Conditions: Alzheimer Disease
Interventions: BIOLOGICAL: AV-1959D|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Instillation of Blue Water (Indigo Carmin®) for Colonoscopy
Status: UNKNOWN
Conditions: Adenoma Detection to Prevent Colorectal Cancer
Interventions: DEVICE: Colonoscopy with blue Indigo Carmin®|DEVICE: Standard colonoscopy with insufflation of air
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparison Between Internal and External Distractors in Osteogenesis
Status: UNKNOWN
Conditions: Micrognathia of Lower Jaw|Retrognathism|Facial Asymmetry
Interventions: DEVICE: Internal Osteogenesis distractor|DEVICE: External Osteogenesis distractor
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low Fluence 1064nm Laser Hair Reduction for Pseudofolliculitis Barbae in Skin Types IV, V, VI
Status: COMPLETED
Conditions: Pseudofolliculitis Barbae
Interventions: PROCEDURE: 1064nm Nd:YAG laser at 12 J/cm2, 20 ms and 10mm spot size.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Risk Assessment for Progression to DMEK Following Cataract Surgery in Fuchs Endothelial Corneal Dystrophy
Status: COMPLETED
Conditions: Fuchs' Endothelial Dystrophy|Cataract
Interventions: PROCEDURE: Phacoemulsification with intraocular lens implantation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Zero Ischemia Laparoscopic Radio Frequency/Microwave Ablation Assisted Enucleation of Renal Cell Carcinoma With T1 Stage
Status: UNKNOWN
Conditions: Kidney Neoplasms
Interventions: PROCEDURE: conventional laparoscopic partial nephrectomy|PROCEDURE: zero ischemia laparoscopic RFA/MVA assisted tumor enucleation (TE)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Educational Needs of Patients With Systemic Vasculitis
Status: COMPLETED
Conditions: Behcet's Disease|Churg-Strauss Syndrome|Vasculitis, Central Nervous System|Giant Cell Arteritis|Wegener Granulomatosis|Henoch-Schoenlein Purpura|Microscopic Polyangiitis|Polyarteritis Nodosa|Takayasu's Arteritis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Treatment of Chemotherapy-induced Nausea and Vomiting
Status: COMPLETED
Conditions: Nausea|Vomiting
Interventions: DRUG: Aprepitant (Emend)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Auricular Acupuncture in Postoperative Pain
Status: COMPLETED
Conditions: Acupuncture
Interventions: DEVICE: electrical auricular acupuncture|DEVICE: P-Stim™ devices were applied without electrical stimulation and acupuncture.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Association Between EEG Changes and Hormonal Response to Tracheal Intubation and Surgical Stimulation
Status: NOT_YET_RECRUITING
Conditions: Abdominal Surgery|Endotracheal Intubation|Surgical Incision|Electroencephalogram
Interventions: PROCEDURE: Endotracheal intubation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Branched-chain Amino Acids in Cancer Cachexia
Status: WITHDRAWN
Conditions: Cancer Cachexia
Interventions: DIETARY_SUPPLEMENT: Pure Encapsulations Branched Chain Amino Acid powder|DIETARY_SUPPLEMENT: control group (no BCAAs provided)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess Adverse Events and Change in Disease State of Intravenously (IV) Infused ABBV-383 of Adult Participants With Relapsed or Refractory Multiple Myeloma in Japan
Status: ACTIVE_NOT_RECRUITING
Conditions: Relapsed/Refractory Multiple Myeloma
Interventions: DRUG: ABBV-383
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Implementation of Illness Management and Recovery in Mental Health Services
Status: COMPLETED
Conditions: Bipolar Disorder|Schizophrenia|Affective Disorders, Psychotic|Mood Disorders|Mental Disorders
Interventions: BEHAVIORAL: Illness Management and Recovery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Assessment of the Safety and Efficacy Study of RGN-259 Ophthalmic Solutions for Neurotrophic Keratopathy : SEER-1
Status: TERMINATED
Conditions: Neurotrophic Keratopathy
Interventions: DRUG: RGN-259|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Docetaxel for Injection (Albumin-bound) in Combination With Bevacizumab in Patients With Ovarian Cancer
Status: RECRUITING
Conditions: Platinum-resistant Recurrent Ovarian Cancer
Interventions: DRUG: Docetaxel for injection (Albumin-bound)|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase III Randomized Study of the Inhalation of Tobramycin in Patients With Cystic Fibrosis
Status: COMPLETED
Conditions: Cystic Fibrosis|Bacterial Infection
Interventions: DRUG: tobramycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Simplified Antibiotic Therapy for Sepsis in Young Infants
Status: COMPLETED
Conditions: Neonatal Sepsis|Sepsis|Infection
Interventions: DRUG: procaine penicillin and gentamicin|DRUG: amoxicillin and gentamicin|DRUG: procaine penicillin, gentamicin, amoxicillin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study in Postmenopausal Women to Investigate the Drug-drug Interaction (DDI) Between Itraconazole(ITZ) and Orally Administered Vilaprisan; Absolute Bioavailability Using Intravenous Microtracer Dose of [14C]Vilaprisan
Status: COMPLETED
Conditions: Clinical Trial, Phase I
Interventions: DRUG: Vilaprisan (BAY1002670)|DRUG: [14C] Vilaprisan|OTHER: Itraconazole(ITZ)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Cordotomy for Refractory Cancer Pain
Status: COMPLETED
Conditions: Advanced Cancers|Pain
Interventions: PROCEDURE: Cordotomy|BEHAVIORAL: Pain/Symptom Questionnaire|PROCEDURE: Sharpness Sensory Testing|PROCEDURE: Heat Pain Sensory Testing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bipolar Versus Mono-polar Needlescopic En Bloc TUR-BT
Status: UNKNOWN
Conditions: Bladder Cancer|Bladder Neoplasm
Interventions: PROCEDURE: Bipolar En bloc TURBT|PROCEDURE: Monopolar En bloc TURBT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ablation of the Pulmonary Artery With High Pulmonary Hypertension During Mitral Valve Surgery
Status: UNKNOWN
Conditions: Pulmonary Hypertension
Interventions: PROCEDURE: Surgical ablation of ganglion plexus pulmonary artery.|PROCEDURE: mitral valve surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Intervention for Virologic Suppression in Youth
Status: RECRUITING
Conditions: HIV/AIDS|Young Adult|Mobile Health|Mental Health Issue|Substance Use
Interventions: OTHER: Standard of Care|BEHAVIORAL: Video-counseling+app
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Treatment of Purulent Flexor Tenosynovitis
Status: RECRUITING
Conditions: Tenosynovitis
Interventions: PROCEDURE: Intraoperative flexor tendon sheath irrigation|PROCEDURE: Postoperative flexor tendon sheath irrigation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Safety, Tolerability and Pharmacokientics of RO5545965 in Patients With Schizophrenia on Risperidone
Status: COMPLETED
Conditions: Schizophrenia
Interventions: OTHER: Placebo|DRUG: RO5545965|DRUG: risperidone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Safety, Tolerability and Pharmacokinetics of AZD9977 After Single Ascending Doses to Healthy Males
Status: COMPLETED
Conditions: Safety|Tolerability|Pharmacokinetics|Healthy Subjects
Interventions: DRUG: AZD9977, oral suspension|DRUG: Placebo, oral suspension|DRUG: AZD9977, oral solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Immunogenicity of Two Dosages of Inactivated, Split-Virion Influenza Vaccine Given by an Alternate Route in the Elderly
Status: COMPLETED
Conditions: Orthomyxoviridae Infection|Influenza|Myxovirus Infection
Interventions: BIOLOGICAL: Inactivated, split-virion influenza vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Dentin Hypersensitivity Using Glass Ionomer Cements
Status: COMPLETED
Conditions: Dentin Hypersensitivity
Interventions: DRUG: Resin-modified glass ionomer cement Clinpro XT|DRUG: Glass Ionomer cement Vidrion R
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of ALN-AAT02 in Healthy Participants and Participants With ZZ Type Alpha-1 Antitrypsin Deficiency Liver Disease
Status: TERMINATED
Conditions: ZZ Type Alpha-1 Antitrypsin Deficiency Liver Disease
Interventions: DRUG: ALN-AAT02|DRUG: Placebo|DRUG: ALN-AAT02
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy or Letrozole Before Surgery in Treating Postmenopausal Women With Breast Cancer That Can Be Removed By Surgery
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: cyclophosphamide|DRUG: docetaxel|DRUG: epirubicin hydrochloride|DRUG: fluorouracil|DRUG: letrozole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adjunctive CB1 Agonist Nabilone in Inpatients With Active Suicidal Ideation
Status: WITHDRAWN
Conditions: Suicidal Ideation
Interventions: DRUG: Nabilone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ultrasound Ablation for Essential Hypertension（FIM）
Status: RECRUITING
Conditions: Uncontrolled Essential Hypertension
Interventions: DEVICE: disposable intravascular ultrasound ablation catheter and ultrasound ablation instrument
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility Study of Balloon Kyphoplasty in Traumatic Vertebral Fractures Needing Surgical Fixation
Status: TERMINATED
Conditions: One or Two Traumatic Vertebral Fractures|Located Between T11 and L5|Balloon Kyphoplasty
Interventions: DEVICE: balloon kyphoplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Impact of MINST With and Without Splinting in Periodontitis Patients With Mobile Anterior Teeth
Status: NOT_YET_RECRUITING
Conditions: Tooth Mobility|Periodontitis
Interventions: PROCEDURE: Splinting|PROCEDURE: MINST alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Oral Bisphosphonates in the Treatment of Osteoporosis of Non-walking Children With Cerebral Palsy
Status: TERMINATED
Conditions: Osteoporosis|Cerebral Palsy
Interventions: DRUG: FOSAMAX|OTHER: PLACEBO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT