pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Effects of Left Nostril Breathing in Young Females Having Cardiovascular Hyper Reactivity to Cold Pressor Test.
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: Left Nostril Breathing|OTHER: Conventional
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: An Evaluation Of PF-03715455 In Moderate To Severe Chronic Obstructive Pulmonary Disease
Status: TERMINATED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Placebo|DRUG: PF-03715455
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Vitamin D for Chemoprevention
Status: COMPLETED
Conditions: Gastrointestinal Cancers|Prostate Cancer|Hypertension
Interventions: DRUG: Vitamin D|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: PK and Safety of Midostaurin in Subjects With Impaired Hepatic Function and Subjects With Normal Hepatic Function
Status: COMPLETED
Conditions: Hepatic Impairment
Interventions: DRUG: Midostaurin|DRUG: Midostaurin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Immunoregulatory Therapy for 2019-nCoV
Status: UNKNOWN
Conditions: 2019 nCoV, PD-1
Interventions: DRUG: PD-1 blocking antibody+standard treatment|DRUG: Thymosin+standard treatment|OTHER: standard treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Colonization and Persistence Capacity of a Multi-strain Probiotics in Pediatric Food Allergy to Milk or Egg.
Status: COMPLETED
Conditions: Food Hypersensitivity|Probiotic
Interventions: DIETARY_SUPPLEMENT: Multi-strain probiotic
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Aza-Ven Followed by Reduced Toxicity Conditioning Regimen (MBF) as Salvage Therapy for Refractory AML.
Status: UNKNOWN
Conditions: Refractory Acute Myeloid Leukemia
Interventions: DRUG: Aza-Ven-allo-HSCT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single Dose Clamp Study to Evaluate Concentration-time Profile and Metabolic Activity of 3 Dose Levels of Afrezza and 3 Dose Levels of Insulin Lispro in Patients With Type 1 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus
Interventions: DRUG: SAR439065|DRUG: Insulin lispro
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Oral Progesterone and Low Dose Aspirin in the Prevention of Preeclampsia
Status: TERMINATED
Conditions: Preeclampsia
Interventions: DRUG: Aspirin|DRUG: Placebo Oral Tablet|DRUG: Progesterone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: VELCADE as Maintenance Treatment in Patients With Multiple Myeloma Following Autologous Peripheral Blood Stem Cell Transplantation (PBSCT)
Status: UNKNOWN
Conditions: Multiple Myeloma
Interventions: DRUG: bortezomib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multicenter Trial of Stem Cell Therapy for Osteoarthritis (MILES)
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: BIOLOGICAL: Bone Marrow Derived MSCs|BIOLOGICAL: Adipose-derived MSCs|BIOLOGICAL: Umbilical Cord Tissue (UCT) MSCs|DRUG: Corticosteroid injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The MEV of 0.5% Ropivacaine in Ultrasound-guided SASIS-FICB
Status: UNKNOWN
Conditions: Nerve Block
Interventions: PROCEDURE: Ultrasound-guided Supra-anterior Superior Iliac Spine Fascia Iliaca Compartment Block (SASIS-FICB) with 0.5% ropivacaine|DRUG: different volume of 0.5% ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study With Mosunetuzumab and Zanubrutinib in R/R Follicular Lymphoma Patients
Status: NOT_YET_RECRUITING
Conditions: Follicular Lymphoma
Interventions: DRUG: Mosunetuzumab in combination with Zanubrutinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Negotiation Training for Caregiver Communication in AD
Status: ACTIVE_NOT_RECRUITING
Conditions: Alzheimer Disease|Cognitive Impairment
Interventions: BEHAVIORAL: Caregiver vs. Patient [Beginner]|BEHAVIORAL: Caregiver vs. Caregiver|BEHAVIORAL: Caregiver vs. Physician|BEHAVIORAL: Caregiver vs. Patient [Advanced]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: LymphoVenous Anastomosis to Prevent Breast Cancer Related Lymphedema
Status: RECRUITING
Conditions: Lymphedema, Breast Cancer
Interventions: PROCEDURE: Axilla dissection + Lymphovenous anastomosis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Using the Musical Track From GC-MRT as a Treatment Booster in Stressful Situations
Status: COMPLETED
Conditions: Social Anxiety
Interventions: BEHAVIORAL: Gaze Contingent Music Reward Therapy|BEHAVIORAL: Music Booster
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Vaginal Baclofen Suppositories in Chronic Pelvic Pain
Status: RECRUITING
Conditions: Chronic Pelvic Pain Syndrome
Interventions: DRUG: 20 mg baclofen vaginal suppository daily per vagina|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Radiotherapy for HCC Involving Type I PVTT
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma
Interventions: PROCEDURE: Hepatectomy alone|RADIATION: Neoadjuvant radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Assess the Bioequivalence of the 4mg Prototype Mini Nicotine Lozenge to the Reference Product (Nicorette) in Healthy Smokers
Status: COMPLETED
Conditions: Tobacco Use Disorder
Interventions: DRUG: Nicotine Prototype Mini lozenge|DRUG: Nicorette Mini Lozenge
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Exercise on Physical Fitness Among Hemodialysis Patients With Chronic Kidney Disease
Status: COMPLETED
Conditions: Hemolysis
Interventions: OTHER: Intradyalisis without exercise programe|OTHER: Intradyalisis with exercise programe
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Clinical Trial of Omalizumab in Participants With Chronic Rhinosinusitus With Nasal Polyps
Status: COMPLETED
Conditions: Nasal Polyps|Chronic Rhinosinusitis
Interventions: DRUG: Omalizumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: EPIC Nitinol Stent System in the Treatment of Atherosclerotic Lesions in Iliac Arteries
Status: COMPLETED
Conditions: Iliac Artery Stenosis
Interventions: DEVICE: Epic™ Nitinol Stent System|DRUG: Anti-platelet therapy|DRUG: Anti-coagulation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Accuracy of Imaging Techniques in Diagnosing Steatohepatitis and Fibrosis in NAFLD Patients
Status: UNKNOWN
Conditions: Non-Alcoholic Fatty Liver Disease|Steatohepatitis, Nonalcoholic|Liver Fibroses
Interventions: DIAGNOSTIC_TEST: Ultrasound and Magnetic Resonance
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Pilot Protocol for the Treatment of Patients With Small Non-Cleaved and Diffuse Large Cell Lymphomas
Status: COMPLETED
Conditions: Burkitt Lymphoma|Lymphoma, Large-Cell, Diffuse|Lymphoma, Small Noncleaved-Cell
Interventions: DRUG: granulocyte-macrophage colony stimulating factor (GM-CSF)
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Migration of Intraureteral Stents Compared to Conventional Double-J Stents.
Status: WITHDRAWN
Conditions: Urologic Diseases|Urological System Complication of Procedure
Interventions: DEVICE: Intraureteral stent|DEVICE: Conventional Double-J stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study of Trifluridine/Tipiracil (TAS-102) in Patients With Metastatic Colorectal Cancer in Asia
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: TAS-102|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Removal of Endotracheal Tube Secretions Comprehensively Until Extubation
Status: UNKNOWN
Conditions: Mechanical Ventilation|Pneumonia
Interventions: DEVICE: CAM (Complete Airway Management) Catheters
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single Versus Multifraction Salvage Spine Stereotactic Radiosurgery for Previously Irradiated Spinal Metastases
Status: RECRUITING
Conditions: Malignant Neoplasms of Eye Brain and Other Parts of Central Nervous System
Interventions: RADIATION: Spine Radiosurgery|BEHAVIORAL: Questionnaires
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: iMeditate at Home for Older Adults With Mild Cognitive Impairment and Caregivers
Status: TERMINATED
Conditions: Mild Cognitive Impairment|Caregivers
Interventions: BEHAVIORAL: Mindfulness meditation delivered via a mobile app
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A 2-stage, Phase III Study to Investigate the Efficacy and Safety of Anifrolumab in Adults With Chronic and/or Subacute Cutaneous Lupus Erythematosus
Status: RECRUITING
Conditions: Cutaneous Lupus Erythematosus
Interventions: COMBINATION_PRODUCT: Anifrolumab|OTHER: Placebo|COMBINATION_PRODUCT: Anifrolumab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Aerobic Exercise for Patients With Bipolar Disorder
Status: UNKNOWN
Conditions: Bipolar Disorder|Cognitive Symptom
Interventions: BEHAVIORAL: aerobic exercise|BEHAVIORAL: Placebo controlled group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Driving Ability Evaluation System to Improve the Conditional Driving License System: Feasibility Study of High-risk Drivers.
Status: RECRUITING
Conditions: Automobile Driving
Interventions: DEVICE: VR Driving Simulator|OTHER: Computerized Neurocognitive Function Test|OTHER: Driver Test Station|OTHER: Short Physical Performance Battery|OTHER: On-road field driving Test
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Ultrafiltration Versus Medical Therapies in the Management of the Cardio Renal Syndrome
Status: UNKNOWN
Conditions: Cardio-renal Syndrome
Interventions: PROCEDURE: ULTRAFILTRATION|PROCEDURE: ENHANCED MEDICAL TREATMENT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Intermittent Fasting on the Incidence of Gestational Diabetes Mellitus Obese Pregnant Women in 3rd Trimester
Status: UNKNOWN
Conditions: Intermittent Fasting|Gestational Diabetes|Obesity
Interventions: DIETARY_SUPPLEMENT: intermittent fasting diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Study of Drotrecogin Alfa (Activated) in Adult Patients With Severe Sepsis at a Low Risk of Death
Status: COMPLETED
Conditions: Sepsis
Interventions: DRUG: Drotrecogin alfa (activated)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of ALG-000184 Drug to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics After Single and Multiple Doses in Healthy Volunteers and CHB Subjects
Status: RECRUITING
Conditions: Chronic Hepatitis B
Interventions: DRUG: ALG-000184|DRUG: Placebo|DRUG: Entecavir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial Evaluating the Effectiveness of a Tattoo Compared to a Clip Applied to Axillary Lymph Nodes in Breast Cancer Patients Who Undergo SLNBx
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DEVICE: Tattoo- Black Eye|DEVICE: clip- HydroMARK
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Automated Mobile Contingency Management for Smoking Cessation: A Pilot RCT (SCC PREVAILgo)
Status: TERMINATED
Conditions: Smoking Cessation
Interventions: BEHAVIORAL: Mobile Contingency Management|BEHAVIORAL: Standard Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Axillary Lymphadenectomy. A Randomized Trial Comparing Bipolar Vessel Sealing To Conventional Technique
Status: COMPLETED
Conditions: Axilla Node Dissection
Interventions: PROCEDURE: bipolar vessel sealing|PROCEDURE: control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Post-market Study of the Endo GIA™ Reinforced Reload With Tri-Staple™ Technology
Status: COMPLETED
Conditions: Non-emergent, Abdominal or Thoracic Procedures
Interventions: DEVICE: Endo GIA™ Reinforced Reload with Tri-Staple™ Technology
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 24-Hour Intraocular Pressure Control With Bimatoprost/Timolol Versus Latanoprost as First Choice
Status: COMPLETED
Conditions: Glaucoma
Interventions: DRUG: Bimatoprost/Timolol, 24-hour intraocular pressure monitoring|DRUG: Latanoprost, 24-hour intraocular pressure monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Permissive Hypercapnia on Concentration of Postoperative Plasma Neurofilament Light
Status: COMPLETED
Conditions: Hypercapnia
Interventions: BEHAVIORAL: permissive hypercapnia|BEHAVIORAL: normocapnia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trendelenburg as a First-line Intervention in Critically Ill, Sedated, Invasively Mechanically Ventilated, Hypotensive Patients
Status: RECRUITING
Conditions: Hypotension|Shock
Interventions: PROCEDURE: Trendelenburg position|PROCEDURE: Semirecumbent position
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Pemetrexed + Platinum Chemotherapy With or Without Pembrolizumab (MK-3475) in Adults With Tyrosine Kinase Inhibitor- (TKI)-Resistant Epidermal Growth Factor Receptor- (EGFR)-Mutated Metastatic Non-squamous Non-small Cell Lung Cancer (NSCLC) (MK-3475-789/KEYNOTE-789)
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer
Interventions: BIOLOGICAL: pembrolizumab|DRUG: pemetrexed|DRUG: carboplatin|DRUG: cisplatin|DRUG: saline solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of MK-8242 Alone and in Combination With Cytarabine in Participants With Acute Myelogenous Leukemia (P07649)
Status: TERMINATED
Conditions: Acute Myelogenous Leukemia (AML)
Interventions: DRUG: MK-8242
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adjuvant Chemotherapy for Elderly Non Frail Patients With an Increased Risk for Relapse of a Primary Carcinoma of the Breast
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Epirubicin, Cyclophosphamide|DRUG: Cyclophosphamide, Methotrexate, 5 FU|DRUG: Capecitabine, Nab-Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effect of ASP8597 in Adult Kidney Transplant Patients
Status: TERMINATED
Conditions: Kidney Transplantation
Interventions: DRUG: ASP8597|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Long Term Safety and Tolerability of NVA237 Versus Tiotropium in Japanese Patients
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: NVA237|DRUG: Tiotropium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Using the Multiphase Optimization Strategy to Adapt Cognitive Processing Therapy
Status: RECRUITING
Conditions: Stress Disorders, Post-Traumatic
Interventions: BEHAVIORAL: Modified A-B-C: Working with Events, Thoughts, and Feelings|BEHAVIORAL: Challenging Questions|BEHAVIORAL: Patterns of Problematic Thinking|BEHAVIORAL: Challenging Beliefs|BEHAVIORAL: Veteran's choice of Module (Safety/Trust/Power and Control/Esteem/Intimacy)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Cerebral Mechanism of Intradermal Acupuncture for Major Depressive Disorder
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: SSRI|DEVICE: SIA|DEVICE: AIA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Interceptive Maxillary Expansion to Relief Anterior Crowding in the Mixed Dentition
Status: RECRUITING
Conditions: Crowding of Anterior Maxillary Teeth|Orthodontics, Interceptive|Orthodontics, Corrective, Palatal Expansion Technique
Interventions: DEVICE: Maxillary expansion device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Single Session Combined Locoregional Therapies for Hepatocellular Carcinoma
Status: UNKNOWN
Conditions: Liver Cancer
Interventions: DRUG: Transarterial chemoembolization (TACE)|PROCEDURE: Radiofrequency ablation combined with TACE|PROCEDURE: Microwave ablation combined with TACE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Doxycycline in Treating Patients With Chronic Rhinosinusitis With Nasal Polyps
Status: TERMINATED
Conditions: Polyp of Nasal Sinus
Interventions: DRUG: Doxycycline|DRUG: methylprednisolone|DRUG: nasal saline spray|DRUG: Flonase|DRUG: sugar pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Pharmacokinetics and Tolerability of Multiple Doses of Eslicarbazepine Acetate and Oxcarbazepine
Status: COMPLETED
Conditions: Partial Epilepsy
Interventions: DRUG: Eslicarbazepine acetate|DRUG: Oxcarbazepine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testosterone Replacement in Diabetes With Vascular Disease (Version 2)
Status: COMPLETED
Conditions: Diabetes Mellitus|Peripheral Vascular Disease
Interventions: DRUG: Testosterone|DRUG: 0.9% saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Paracetamol And Ibuprofen/Indomethacin in Closing Patent Ductus Arteriosus
Status: RECRUITING
Conditions: Patent Ductus Arteriosus
Interventions: DRUG: Paracetamol 10Mg/mL|DRUG: 0.45% Sodium Chloride|DRUG: Ibuprofen|DRUG: Indomethacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Anesthesia on Expression of Programmed Death-1 and Programmed Death-1 Ligand in Breast Cancer
Status: UNKNOWN
Conditions: Programmed Cell Death 1
Interventions: PROCEDURE: Thoracic Paravertebral block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Development of Novel Imaging and Molecular Biomarkers of Fibrosis in Patient With Ulcerative Colitis
Status: NOT_YET_RECRUITING
Conditions: Ulcerative Colitis
Interventions: PROCEDURE: to determine molecular and epigenetic biomarkers
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Carlizumab Plus Sovantinib in Second-line Treatment of Advanced or Metastatic Cholangiocarcinoma
Status: NOT_YET_RECRUITING
Conditions: Cholangiocarcinoma
Interventions: DRUG: Carrelizumab|DRUG: Solfantinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Remicade Study in Psoriatic Arthritis Patients Of Methotrexate-Naïve Disease (RESPOND) (Study P04422)
Status: COMPLETED
Conditions: Arthritis, Psoriatic
Interventions: DRUG: Infliximab + methotrexate (IFX + MTX)|DRUG: Methotrexate (MTX)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improvisational Movement for People With Memory Loss and Their Caregivers
Status: COMPLETED
Conditions: Alzheimer's Disease (Incl Subtypes)|Dementia|Mild Cognitive Impairment
Interventions: BEHAVIORAL: Dance Group|BEHAVIORAL: Non-Group Dance|BEHAVIORAL: Social Group|BEHAVIORAL: No Contact
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: An Open-Label Study of Atomoxetine in Adolescents With Attention-Deficit/Hyperactivity Disorder
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: DRUG: Atomoxetine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Dexmedetomidine on Perioperative Internal Environment and Rehabilitation of Patients Undergoing Gastrointestinal Malignant Tumor Resection
Status: COMPLETED
Conditions: Dexmedetomidine|Perioperative|Electrolyte
Interventions: DRUG: Dexmedetomidine|DRUG: Dexmedetomidine|DRUG: Dexmedetomidine|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Examining the Effectiveness of a Connective Tissue Matrix Implant in Reducing Post-operative Pain and Narcotic After Outpatient Arthroscopic Shoulder Surgery
Status: TERMINATED
Conditions: Arthroscopic Shoulder Surgery|Pain, Postoperative
Interventions: DEVICE: Extracellular Matrix Graft Injectable Implant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Protein Quality of Fava Bean and Honey Chlorella in Humans
Status: NOT_YET_RECRUITING
Conditions: Protein Quality of Chlorella and Fababean Meat Analogue
Interventions: DIETARY_SUPPLEMENT: Single meal containing 20 g of 15N intrinsically labelled protein from honey chlorella|DIETARY_SUPPLEMENT: Single meal containing 20 g of 15N intrinsically labelled protein from faba bean meat analogue
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Use of 31P MRS to Assess Brain NAD+ in Healthy Current and Former Collegiate Athletes
Status: COMPLETED
Conditions: Concussion, Mild
Interventions: DIETARY_SUPPLEMENT: Nicotinamide Riboside|OTHER: Matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SCREENING
Clinical trial: A Study of Duvelisib Versus Gemcitabine or Bendamustine in Participants With Relapsed/Refractory Nodal T Cell Lymphoma With T Follicular Helper (TFH) Phenotype
Status: NOT_YET_RECRUITING
Conditions: Lymphoma
Interventions: DRUG: Duvelisib|DRUG: Gemcitabine|DRUG: Bendamustine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, and Pharmacokinetics of Multiple Doses of Oral EC5026 in Healthy Subjects
Status: RECRUITING
Conditions: Healthy Subjects
Interventions: DRUG: EC5026 oral tablet|DRUG: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety of Expanded Haploidentical Natural Killer Cells for Leukemia
Status: COMPLETED
Conditions: Leukemia, Acute Myeloid|Leukemia, Acute Lymphoblastic
Interventions: BIOLOGICAL: Expanded Haploidentical Natural Killer cells|DRUG: IL-2
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Squalamine Lactate for the Treatment of Macular Edema Related to Retinal Vein Occlusion
Status: COMPLETED
Conditions: Retinal Vein Occlusion|Macular Edema
Interventions: DRUG: ranibizumab|DRUG: Squalamine Lactate Ophthalmic Solution, 0.2%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Lower Limb Exproprioception Training in Virtual Environment on Locomotion Performance in Stroke Patients
Status: UNKNOWN
Conditions: Spatial Perception|Stroke|Virtual Reality|Exercise Training|Exproprioception
Interventions: OTHER: Virtual reality foot placement training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy Plus Gefitinib for Advanced Lung Adenocarcinoma and Sensitive EGFR Mutations: a Randomized Controlled Trial
Status: UNKNOWN
Conditions: Lung Adenocarcinoma
Interventions: DRUG: Pemetrexed plus carboplatin combined with gefitinib|DRUG: Gefitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Validation of a Novel Dabigatran Based Peri-Operative Bridging Anticoagulation Protocol for Patients on Chronic Warfarin Therapy
Status: WITHDRAWN
Conditions: Venous Thromboses
Interventions: DRUG: Dabigatran.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Efficacy of Using Pentoxifylline in Patients Undergoing Breast Cancer Surgery
Status: RECRUITING
Conditions: Post-Surgical Complication|Breast Cancer Surgery
Interventions: DRUG: Pentoxifylline|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: App-based Psychosocial Intervention to Enhance Quality of Life in Arabic-speaking Refugees Residing in Switzerland
Status: COMPLETED
Conditions: Quality of Life|Stigma, Social|Depression|PTSD|Anxiety
Interventions: BEHAVIORAL: Sui App (SRK)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Home-Based Exercise and Weight Control Program for Pain Control in Overweight Elderly With Osteoarthritis of the Knee
Status: COMPLETED
Conditions: Chronic Diseases|Obesity|Osteoarthritis|Pain
Interventions: OTHER: Weight Control Nutritional Program|OTHER: Home-based exercise program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Coronary Computed Tomographic Angiography in Intermediate-risk Chest Pain Patients
Status: RECRUITING
Conditions: Chest Pain|Acute Coronary Syndrome|Coronary Artery Disease
Interventions: DIAGNOSTIC_TEST: Coronary computed tomopraphic angiography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Mechanism of Response to IMFINZI Neoadjuvant Therapy in Non-small Cell Lung Cancer Patients Based on Multiple-omics Models
Status: RECRUITING
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: Durvalumab|DRUG: Albumin Paclitaxel|DRUG: Carboplatin/Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chimeric Antigen Receptor T Cells (CART) Therapy in Refractory/Relapsed B Cell Hematologic Malignancies
Status: UNKNOWN
Conditions: Leukemia, B-Cell|Lymphoma, B-Cell
Interventions: BIOLOGICAL: CD19CART
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Telaglenastat + Talazoparib In Prostate Cancer
Status: UNKNOWN
Conditions: Prostate Cancer Metastatic
Interventions: DRUG: Telaglenastat|DRUG: Talazoparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of Sintilimab Plus Apatinib and Chemotherapy in Patients With HER-2 Negative Microsatellite Stability (MSS) Advanced or Metastatic Gastric (GC) or Gastroesophageal Junction (GEJ) Cancer
Status: RECRUITING
Conditions: Gastric Cancer|Chemotherapy|Immunotherapy
Interventions: DRUG: Sintilimab 200 mg, intravenously (IV) every 3 weeks(Q3W)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Remimazolam and Postoperative Nausea and Vomiting in High-risk Patients
Status: COMPLETED
Conditions: Postoperative Nausea and Vomiting|Benzodiazepine|High-risk Patients
Interventions: DRUG: Remimazolam|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Cognitive Behavioral Therapy Via a Smartphone Application on Bulimia Nervosa and Binge Eating Disorder Symptoms
Status: WITHDRAWN
Conditions: B.E.D AND BULIMIA PATIENT|SMARTPHONE OWNER|BASIC ENGLISH SPEAKER
Interventions: BEHAVIORAL: application|OTHER: psychotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Study of Biting Force of Injection Molded PEEK and Bre.Flex for Removable Partial Dentures.
Status: UNKNOWN
Conditions: Biting
Interventions: OTHER: bre.flex|OTHER: PEEK
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: CORonary Diet Intervention With Olive Oil and Cardiovascular PREVention
Status: COMPLETED
Conditions: Myocardial Infarction|Unstable Angina|Malignancy|Cognitive Decline|Diabetes Mellitus|Metabolic Syndrome
Interventions: BEHAVIORAL: Mediterranean Diet|BEHAVIORAL: Low Fat Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Prevention of De Novo HCV With Antiviral HCV Therapy Post-Liver and Post-Kidney Transplant
Status: COMPLETED
Conditions: Hepatitis C|Transplantation Disease Transmission
Interventions: DRUG: Sofosbuvir/Velpatasvir|DRUG: Sofosbuvir/Velpatasvir/Voxilaprevir
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Efficacy of Gemcitabine and Nab-palitaxe Combined With Cadonilimab Sequential Short-course Radiotherapy in the Treatment of Patients With Locally Advanced Pancreatic Ductal Adenocarcinoma
Status: NOT_YET_RECRUITING
Conditions: Locally Advanced Pancreatic Ductal Adenocarcinoma
Interventions: DRUG: Cadonilimab|DRUG: Gemcitabine|DRUG: Nab paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Promoting Shared Decision Making for Severe Aortic Stenosis
Status: NOT_YET_RECRUITING
Conditions: Aortic Stenosis
Interventions: BEHAVIORAL: Decision Aid|BEHAVIORAL: Shared Decision Making Skills Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Clinical Outcomes of Percutaneous Nephrolithotomy Following Retrograde Percutaneous Nephrostomy Access Using Novel Device in Comparison to Antegrade Access
Status: NOT_YET_RECRUITING
Conditions: Kidney Stone
Interventions: DEVICE: retrograde nephrostomy|DEVICE: antegrade nephrostomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: S0115, High-Dose Melphalan and Autologous Peripheral Stem Cell Transplantation in Treating Patients With Multiple Myeloma or Primary Systemic Amyloidosis
Status: COMPLETED
Conditions: Multiple Myeloma|Plasma Cell Myeloma
Interventions: BIOLOGICAL: filgrastim|DRUG: cyclophosphamide|DRUG: dexamethasone|DRUG: melphalan|DRUG: thalidomide|PROCEDURE: peripheral blood stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: S.T.A.N.D. Alacrity Center Signature Project
Status: RECRUITING
Conditions: Depression|Anxiety
Interventions: BEHAVIORAL: Self-Guided Online Prevention|BEHAVIORAL: Coach-Guided Online Cognitive Behavioral Therapy|BEHAVIORAL: Clinician-Delivered Psychological and Psychiatric Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Demonstrate the Safety and Preformance of the SRS Device for the Treatment of Pelvic Organ Prolapse
Status: COMPLETED
Conditions: Anterior Vaginal Wall Prolapse|Vaginal Apex/Uterine Prolapse
Interventions: DEVICE: SRS
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open-label Prospective Clinical Trial Evaluating the Safety and Efficacy of Biosynthetic CLP-PEG-MPC Corneal Implants in Patients Undergoing High-risk Deep Anterior Lamellar Keratoplasty.
Status: WITHDRAWN
Conditions: High-risk Corneal Transplantation|Corneal Blindess|Corneal Inflammation|Deep Anterior Lamellar Keratoplasty
Interventions: DEVICE: CLP-PEG-MPC|PROCEDURE: Human donor cornea penetrating keratoplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Resistance and Aerobic Training, Relationship With Birth Weight in Colombian Children
Status: COMPLETED
Conditions: Resistance Training|Cardiovascular Risk|Low Birth Weight
Interventions: BEHAVIORAL: Muscular Resistance training|BEHAVIORAL: Cardiorespiratory training|BEHAVIORAL: Habitual training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Investigation of Vascular Relaxing Effects of Candesartan and Pioglitazone.
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: Pioglitazone (drug) and/or candesartan (drug)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Psychologic Impact of COVID-19 Pandemic on the Hospital Staff of the Nouvelle Aquitaine Area
Status: NOT_YET_RECRUITING
Conditions: Covid19|Personnel, Hospital|Work-Related Condition|Work-Related Stress Disorder
Interventions: OTHER: self administered questionnaire
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Post-operative Haloperidol Versus Placebo for Prevention of Post-operative Delirium After Acute Hip Surgery
Status: COMPLETED
Conditions: Post-Operative Delirium|Hip Fracture
Interventions: DRUG: Haloperidol|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Impact of a Nocturnal Pressure Controlled Ventilation on Mechanical Ventilation Weaning Duration in Patients With Chronic Obstructive Respiratory Diseases
Status: WITHDRAWN
Conditions: Noctural Ventilatory Mode and Weaning Duration
Interventions: PROCEDURE: Nocturnal controlled pressure control ventilation|PROCEDURE: Pressure support ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Partnering for Change in Sweden - Intervention to Increase Pupils' Engagement and Participation
Status: UNKNOWN
Conditions: Child Health
Interventions: BEHAVIORAL: Partnering for change (P4C-Swe)|BEHAVIORAL: Treatment as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Socket Augmentation Using Platelet Concentrates, Atorvastatin Gel or Combination
Status: COMPLETED
Conditions: Alveolar Socket Preservations
Interventions: COMBINATION_PRODUCT: PRGF/ATV|DRUG: ATV gel|BIOLOGICAL: PRF|BIOLOGICAL: PRGF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dexmedetomidine and Long-term Outcome in Elderly Patients After Surgery
Status: COMPLETED
Conditions: Aged|Surgical Procedures, Operative|Delirium|Dexmedetomidine|Mortality|Long-term Survivors
Interventions: DRUG: dexmedetomidine|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Oral Water in Healthy Volunteers on Cardiac Output, Regional Flow and Microcirculation in Healthy Volunteers
Status: RECRUITING
Conditions: Intravenous Fluids|Pharmacodynamics|Fluid Therapy|Fluid Responsiveness|Fluid Challenge
Interventions: OTHER: saline intravenous administration|OTHER: oral water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study on the Influence of Climatic and Environmental Factors on Respiratory Diseases in Sanya, Hainan Province, China.
Status: RECRUITING
Conditions: Asthma|Allergic Rhinitis|Chronic Obstructive Pulmonary Disease(COPD)|Atopic Dermatitis|Eczema|Urticaria|Bronchitis|Bronchiectasis Adult|Emphysema
Interventions: OTHER: Climate and environment in Sanya
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effects of Neuromuscular Electrical Stimulation on Swallowing Functions in Stroke Patients With Dysphagia
Status: COMPLETED
Conditions: Stroke|Swallowing Disorder|Dysphagia|Stroke, Complication|Cerebrovascular Accident
Interventions: BEHAVIORAL: Procedure: Traditional Dysphagia Therapy (TDT)|DEVICE: Procedure: Neuromuscular Electrical Stimulation with TDT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intravenous and Intraperitoneal Paclitaxel, Intraperitoneal Cisplatin, and Intravenous Bevacizumab for the Initial Treatment of Optimal Stage II or III Ovarian, Primary Peritoneal, and Fallopian Tube Cancer
Status: COMPLETED
Conditions: Ovarian Cancer|Primary PERITONEUM|Fallopian Tube Cancer
Interventions: DRUG: Paclitaxel,Cisplatin, Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Evaluation of Prismocitrate 18 in Patients Receiving CRRT
Status: RECRUITING
Conditions: Regional Citrate Anticoagulation (RCA)|Continuous Renal Replacement Therapy (CRRT)|Acute Kidney Injury (AKI)
Interventions: DRUG: Prismocitrate 18
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Evaluation of a Human Papillomavirus (HPV) Vaccine in Healthy Female Control Subjects From the GSK HPV 023 Study
Status: COMPLETED
Conditions: Infections, Papillomavirus
Interventions: BIOLOGICAL: CervarixTM (GSK580299)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Azacitidine Combined With Pembrolizumab and Epacadostat in Subjects With Advanced Solid Tumors (ECHO-206)
Status: TERMINATED
Conditions: Solid Tumors|Advanced Malignancies|Metastatic Cancer
Interventions: DRUG: Azacitidine|DRUG: Pembrolizumab|DRUG: Epacadostat|DRUG: INCB057643|DRUG: Pembrolizumab|DRUG: Epacadostat|DRUG: INCB059872
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Atorvastatin Effects On Arterial Stiffness In Hemodialysis
Status: COMPLETED
Conditions: Arterial Stiffness
Interventions: DRUG: Atorvastatin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Analgesic Effects of LED Light on Temporomandibular Disorders.
Status: COMPLETED
Conditions: Temporomandibular Disorder
Interventions: RADIATION: Red LED|RADIATION: INFRARED LED|RADIATION: LASER
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Canine Occlusal Relationship Changes After Stainless-Steel Crown Placement Under General Anesthesia
Status: COMPLETED
Conditions: Full Mouth Rehabilitation|Canine Overlap Relation|General Anesthesia
Interventions: DEVICE: Digital Caliper (Shenzhen Jiabaili Electronic Commerce Co., Ltd)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Multiple Interventions to Accelerate the Return to the Pre-event Level of Functioning After a TIA and Minor Stroke
Status: UNKNOWN
Conditions: Transient Ischemic Attack|Minor Stroke
Interventions: BEHAVIORAL: Cognitive training|BEHAVIORAL: Physical exercise|BEHAVIORAL: Behavioral: Nutrition education|BEHAVIORAL: Psychoeducation|OTHER: Diagnosis and correction of hearing impairment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Detecting the Changes of Swallowing Function in Tongue Cancer Patients Receiving Mandibular-lip Split or Pull-through Resection Surgeries
Status: NOT_YET_RECRUITING
Conditions: Swallowing Function
Interventions: PROCEDURE: pull through group|PROCEDURE: mandibular-lip split group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: High Dose PPI Triple Therapy Versus Sequential Therapy for Helicobacter Pylori Eradication
Status: COMPLETED
Conditions: Dyspepsia|Helicobacter-associated Gastritis|Stomach Disorders
Interventions: DRUG: Double dose of PPI|DRUG: sequence of drug use
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testing the Effects of Singapore's Front-of-Pack Healthier Choice Symbol Label With or Without a Physical Activity Equivalent Label
Status: COMPLETED
Conditions: Obesity|Diabetes|Diet, Healthy
Interventions: BEHAVIORAL: Healthier Choice Symbol|BEHAVIORAL: Physical Activity Equivalent label
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH