pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Effect of Acupuncture on Patients With Chronic Obstructive Pulmonary Disease
Status: UNKNOWN
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: OTHER: Acupuncture|DRUG: Conventional drug|OTHER: Acupuncture plus conventional drug
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Avutometinib, Defactinib, and Letrozole in People With Low-Grade Serous Ovarian Cancer
Status: RECRUITING
Conditions: Low-Grade Serous Ovarian Cancer
Interventions: DRUG: Avutometinib|DRUG: Defactinib|DRUG: Letrozole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Precision Diagnosis Directing HDACi Chidamide Target Therapy for Adult T-LBL/ALL
Status: UNKNOWN
Conditions: Leukemia|Leukemia, Acute|Adult Lymphoblastic Lymphoma|Leukemia, Lymphoblastic|Leukemia, T Cell|Adult Acute Lymphoblastic Leukemia|Lymphoblastic Lymphoma|Lymphoblastic Leukemia
Interventions: DRUG: Dexamethasone|DRUG: vincristine|DRUG: Cyclophosphamide|DRUG: Idarubicin|DRUG: Pegaspargase|DRUG: Adriamycin|DRUG: Methotrexate|DRUG: 6-mercaptopurine.|DRUG: Etoposide|DRUG: Cytarabine|PROCEDURE: Bone marrow aspiration|PROCEDURE: Intrathecal injection|RADIATION: Radiation therapy|GENETIC: NGS|PROCEDURE: allogeneic hematopoietic stem cell transplantation|DIAGNOSTIC_TEST: Flow-MRD|DIAGNOSTIC_TEST: FISH|DIAGNOSTIC_TEST: Flow immunophenotyping|DIAGNOSTIC_TEST: Karyotyping|DRUG: Chidamide|DIAGNOSTIC_TEST: PET-CT scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BE Study of Albuterol Sulfate Inhalation Aerosol 90 mcg Per Actuation in Patients With Stable Mild Asthma
Status: NOT_YET_RECRUITING
Conditions: Bronchial Asthma
Interventions: DRUG: Albuterol Sulfate Inhalation Aerosol (90 mcg per actuation)|DRUG: Ventolin HFA 90Mcg/Actuation Inhalation Aerosol_#1|DRUG: Ventolin HFA, 90 Mcg/Inh Inhalation Aerosol_#2|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Determine the Pharmacokinetics of GSK961081 and Fluticasone Furoate When Administered Alone or in Combination
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: GSK961081|DRUG: Fluticasone furoate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prognostic Impact of Delta-haemolysin Production Deficiency in Staphylococcus Aureus on the Prognosis of Infected Implant Treated by DAIR
Status: RECRUITING
Conditions: Bone and Joint Infection|Staphylococcus Aureus
Interventions: OTHER: Delta-haemolysin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Flexible urétéroscopy Versus Extracorporeal Shockwave Lithotripsy in Renal Calculi
Status: COMPLETED
Conditions: Extracorporeal Shockwave Lithotripsy, Flexible Ureteroscopy
Interventions: PROCEDURE: flexible ureteroscopy|PROCEDURE: extracorporeal shockwave lithotripsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: In-office Bleaching Using a Violet Light
Status: COMPLETED
Conditions: Tooth Bleaching|Dentin Sensitivity
Interventions: PROCEDURE: 35% Hydrogen peroxide bleaching|PROCEDURE: 30% Carbamide peroxide bleaching|PROCEDURE: Violet LED bleaching 1|PROCEDURE: Violet LED bleaching 2|PROCEDURE: Photochemical protocol 1|PROCEDURE: Photochemical protocol 2|PROCEDURE: Hybrid technique 1|PROCEDURE: Hybrid technique 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Infections and Autoimmunity: Autobodies Screening in Multiple Sclerosis
Status: UNKNOWN
Conditions: Multiple Sclerosis
Interventions: PROCEDURE: Serum antibodies to infectious agents using the BioPlex 2200 and complementary EIA kits
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effects of Berberine Hydrochloride and Bifidobacterium in Diabetes Mellitus Prevention and Treatment
Status: WITHDRAWN
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Bifidobacterium viable pharmaceutics|DRUG: Berberine Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of EGT0001442 in Subjects With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus Type 2
Interventions: DRUG: EGT0001442|DRUG: Placebo capsules to match EGT0001442
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Web-based Peer Navigation Program for Men With Prostate Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Cancer
Interventions: BEHAVIORAL: Peer navigation|OTHER: Active wait list control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluate the Safety and Efficacy of Toripalimab Combined With Bevacizumab Versus Sorafenib Therapy for HCC
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Hepatocellular Carcinoma (HCC)
Interventions: COMBINATION_PRODUCT: Toripalimab combined with Bevacizumab|DRUG: Sorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of a Multispecies Probiotic on Reducing the Incidence of Antibiotic-associated Diarrhoea in Children.
Status: COMPLETED
Conditions: Antibiotic-associated Diarrhea
Interventions: DIETARY_SUPPLEMENT: Multispecies probiotic|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: PROcalcitonin Impact on Antibiotic Reduction, adverSe Events and AVoidable healthcarE Costs (ProSAVE): A RCT
Status: COMPLETED
Conditions: Pneumonia, Bacterial
Interventions: DIAGNOSTIC_TEST: procalcitonin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Therapeutic Equivalence Study in Subjects With Primary Open Angle Glaucoma or Ocular Hypertension
Status: COMPLETED
Conditions: Primary Open Angle Glaucoma|Ocular Hypertension
Interventions: DRUG: Brinzolamide ophthalmic suspension|DRUG: Azopt®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of 4-regimen (SP, FL/Tax, FL/Doc, FOLFOX) in Patients With Recurrent or Metastatic Gastric Cancer
Status: COMPLETED
Conditions: Recurrent or Metastatic Gastric Cancer
Interventions: DRUG: SP|DRUG: FL/Tax|DRUG: FL/Doc|DRUG: FOLFOX
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Comparison of Two Crosslinked Hyaluronate for the Treatment of Osteoarthritis Pain
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: DEVICE: HYAJOINT Plus|DEVICE: Durolane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial to Compare the Efficacy, Safety and Tolerability of Combinations of 3 Anti-malarial Drugs Against Combinations of 2 Anti-malarial Drugs (Asia)
Status: COMPLETED
Conditions: Plasmodium Falciparum Malaria (Uncomplicated)
Interventions: DRUG: Artemether-lumefantrine+amodiaquine|DRUG: Artemether-lumefantrine+placebo|DRUG: Artesunate-mefloquine+piperaquine|DRUG: Artesunate-mefloquine+placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Phase I Clinical Trial to Investigate the Safety, Tolerability and Pharmacokinetic Characteristics of LC28-0126.
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: LC28-0126|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Rebif® in Clinically Isolated Syndrome and Relapsing Multiple Sclerosis Using RebiSmart™
Status: COMPLETED
Conditions: Relapsing Multiple Sclerosis|Clinically Isolated Syndrome
Interventions: DRUG: Rebif
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Therapy With 3BNC117 and 10-1074 in HIV-Infected Individuals
Status: TERMINATED
Conditions: HIV
Interventions: BIOLOGICAL: 3BNC117 and 10-1074|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Antidepressant Efficacy of Psychotherapy and Citalopram in Patients With Breast Cancer and Major Depression
Status: TERMINATED
Conditions: Breast Cancer|Major Depressive Episode
Interventions: DRUG: Citalopram|BEHAVIORAL: Psychotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Proof of Concept Study of BMS-823778 to Assess the Effects on Atherosclerosis
Status: WITHDRAWN
Conditions: Atherosclerotic Cardiovascular Disease
Interventions: DRUG: BMS-823778|DRUG: BMS-823778|DRUG: Placebo matching with BMS-823778
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Bovine Milk Immunoglobulin Against CS17 and CsbD
Status: COMPLETED
Conditions: Travelers' Diarrhea
Interventions: BIOLOGICAL: Anti-CsbD Bovine IgG|OTHER: Placebo|BIOLOGICAL: Anti-CS17 Bovin IgG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Reproductive Capacity and Iron Burden in Thalassemia
Status: COMPLETED
Conditions: THALASSEMIA MAJOR
Interventions: OTHER: Blood Draw/Semen Exam|OTHER: Retrospective data/Chart Review/Relevant Clinical Results|OTHER: Pituitary MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Therapeutic Intensification Plus Immunomodulation to Decrease the HIV-1 Viral Reservoir
Status: COMPLETED
Conditions: HIV Infection
Interventions: BIOLOGICAL: DNA + HIV-rAd5 vaccine|DRUG: ART intensification (raltegravir)|DRUG: ART intensification (maraviroc)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of PCSK9 Inhibitors on Coronary Atherosclerotic Plaques Derived From Optical Coherence Tomography
Status: RECRUITING
Conditions: Coronary Artery Disease|Optical Coherence Tomography
Interventions: DRUG: PCSK9 inhibitor|DRUG: Statin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study of Dose dE-eScalaTion IN prostATe radIOtherapy usiNg the MRL
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Cancer
Interventions: RADIATION: De-escalated radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Transversus Abdominis Plane Block on Anti-inflammatory Response
Status: UNKNOWN
Conditions: Liver Transplant; Complications|Inflammatory Response
Interventions: PROCEDURE: Transversus abdominous plane block (TAP Block)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Pilot Study of Sedation With Propofol in Refractory Pains Due to Care in Palliative Care Unit
Status: COMPLETED
Conditions: Refractory Pains|End of Life Patients
Interventions: DRUG: sedation with propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Peg-interferon for Inactive Chronic Hepatitis B Carriers
Status: UNKNOWN
Conditions: Chronic Hepatitis, B Virus|Carrier of Viral Hepatitis Type B
Interventions: DRUG: Peginterferon Alfa-2A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I Study of LTC004 Combin With FC in Patients With Advanced/Metastatic Malignancies Tumor
Status: NOT_YET_RECRUITING
Conditions: Adult Solid Tumor
Interventions: DRUG: LTC004 in Combination With Cyclophosphamide and Fludarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of NUV-422 in Combination With Fulvestrant in Patients With HR+HER2- aBC
Status: WITHDRAWN
Conditions: Advanced Breast Cancer|Metastatic Breast Cancer|Breast Cancer|Breast Carcinoma|Cancer of the Breast|Cancer of Breast|Malignant Tumor of Breast|Breast Tumor
Interventions: DRUG: NUV-422|DRUG: Fulvestrant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Identification of Microcirculation After Surgical Treatment of Rupture of the Achilles Tendon
Status: COMPLETED
Conditions: Microcirculation|Achilles Tendon Rupture
Interventions: PROCEDURE: Stitches|PROCEDURE: Fibrin-glue|PROCEDURE: Stitches and Fibrin-glue
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Trial Investigating the Safety, Tolerability, Pharmacokinetics (the Exposure of the Trial Drug in the Body) and Pharmacodynamics (the Effect of the Investigated Drug on the Body) of Insulin 287 in Subjects With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: Insulin icodec|DRUG: placebo|DRUG: insulin degludec|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Atropine (0.02%, 0.04%) Combined With Defocus DIMS for Moderate and High Myopia Control
Status: RECRUITING
Conditions: Myopia
Interventions: DEVICE: DIMS|DRUG: The 0.02% ATP Group|DRUG: The 0.04% ATP Group|COMBINATION_PRODUCT: 0.02%ATP+DIMS|COMBINATION_PRODUCT: 0.04%ATP+DIMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Imatinib Mesylate and Chemotherapy in Treating Patients With Extensive-Stage Small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DRUG: cisplatin|DRUG: imatinib mesylate|DRUG: irinotecan hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Can Ondansetron Prevent Neonatal Abstinence Syndrome (NAS) in Babies Born to Narcotic-dependent Women
Status: COMPLETED
Conditions: Narcotic Addiction|Neonatal Abstinence Syndrome
Interventions: DRUG: Ondansetron|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Induced Hyperammonaemia on Sleep and Melanopsin-mediated Pupillary Light Response in Patients With Liver Cirrhosis
Status: COMPLETED
Conditions: Hepatic Encephalopathy|Liver Cirrhosis|Sleep Disturbance
Interventions: DIETARY_SUPPLEMENT: Amino Acid Challenge (AAC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Single Doses of PF-06852231 in Healthy Subjects
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Placebo|DRUG: PF-06852231
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Study to the Optimal Duration of Therapy With Oral Angiogenesis Inhibitors
Status: UNKNOWN
Conditions: Renal Cell Carcinoma|Gastrointestinal Stromal Tumor
Interventions: DRUG: usage oral angiogenesis inhibitor|DRUG: stop oral angiogenesis inhibitor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness and Safety of Ezetimibe Added to Atorvastatin in Patients With High Cholesterol and Coronary Heart Disease (Study P03740)
Status: COMPLETED
Conditions: Hypercholesterolemia|Coronary Heart Disease
Interventions: DRUG: ezetimibe|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Safety and Performance PMCF Investigation of the Avance® Solo NPWT System in Surgically Closed Incisions
Status: UNKNOWN
Conditions: Incision, Surgical|Surgical Incision|Surgical Wound|Surgical Wound, Recent|Surgical Wound Dehiscence
Interventions: DEVICE: Avance® Solo NPWT System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study To Evaluate Paired Treatment With An Alexandrite Laser And Radiofrequency Microneedling For Facial Aging
Status: COMPLETED
Conditions: Wrinkle|Photoaging|Dyschromia
Interventions: DEVICE: RF device|DEVICE: Microneedling device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EMpagliflozin to PREvent worSening of Left Ventricular Volumes and Systolic Function After Myocardial Infarction
Status: ACTIVE_NOT_RECRUITING
Conditions: Myocardial Infarction
Interventions: DRUG: Empagliflozin 10 MG|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Adaptive Staged Stereotactic Body Radiation Therapy in Treating Patients With Spinal Metastases That Cannot Be Removed by Surgery
Status: COMPLETED
Conditions: Melanoma|Metastatic Malignant Neoplasm in the Spine|Renal Cell Carcinoma|Soft Tissue Sarcoma|Spinal Cord Compression
Interventions: RADIATION: Image-Guided Adaptive Radiation Therapy|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration|RADIATION: Stereotactic Body Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized Controlled Trial to Evaluate the Effect of White Noises and Parental Voices as Protectors Against Noise Damage in a Neonatal Intensive Care Unit
Status: RECRUITING
Conditions: Premature Infant Disease
Interventions: BEHAVIORAL: White Noises and Maternal and/or Paternal voices
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Preoperative Relaxation Training and Acupuncture to Minimize Perioperative Symptoms in Breast Cancer Patients
Status: COMPLETED
Conditions: Breast Neoplasms
Interventions: BEHAVIORAL: relaxation training|OTHER: acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Progressive Muscle Relaxation and Deep Breathing Exercises
Status: COMPLETED
Conditions: Progressive Muscle Relaxation|Deep Breath|COPD
Interventions: BEHAVIORAL: Progressive Muscle Relaxation|BEHAVIORAL: Deep Breathing Exercise Group-DBE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: FEM-PrEP (Truvada®): Study to Assess the Role of Truvada® in Preventing HIV Acquisition in Women
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Truvada|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluate the Efficacy and Safety of Saxagliptin Added to Insulin Monotherapy or to Insulin Combined With Metformin in Chinese Subjects With Type 2 Diabetes Who Have Inadequate Glycaemic Control
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Saxagliptin 5mg|DRUG: Placebo for Saxagliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Middle Cerebral Artery Velocity and Oxygen Saturation of the Brain During Carotid Endarterectomy
Status: UNKNOWN
Conditions: Cerebral Oxygen Saturation,MCA Velocity,Intraoperative Neurological Symptoms During Carotid Endarterectomy
Interventions: DEVICE: transcranial Doppler (TCD) and INVOS monitor
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: 3 Tesla Magnetic Resonance Guided High Intensity Focused Ultrasound in the Treatment of Pain From Bone Metastases of Solid Tumors
Status: TERMINATED
Conditions: Solid Tumors
Interventions: PROCEDURE: MR-HIFU Treatment|DRUG: MR contrast media and medications|PROCEDURE: MR images
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Abemaciclib (LY2835219) Plus Tamoxifen or Abemaciclib Alone in Women With Metastatic Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Breast Cancer
Interventions: DRUG: Abemaciclib|DRUG: Tamoxifen|DRUG: Prophylactic Loperamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Washing COVID-19 Away With a Hypertonic Seawater Nasal Irrigation Solution
Status: COMPLETED
Conditions: SARS-CoV2 Infection
Interventions: OTHER: Hypertonic seawater solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Avelumab With Bempegaldesleukin With or Without Talazoparib or Enzalutamide in Advanced or Metastatic Solid Tumors
Status: TERMINATED
Conditions: Squamous Cell Carcinoma of the Head and Neck (SCCHN)|Metastatic Castration Resistant Prostate Cancer (mCRPC)
Interventions: DRUG: avelumab|DRUG: Bempegaldesleukin|DRUG: talazoparib|DRUG: enzalutamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effect of ASP7991 in Secondary Hyperparathyroidism Patients Undergoing Hemodialysis
Status: COMPLETED
Conditions: Secondary Hyperparathyroidism
Interventions: DRUG: ASP7991|DRUG: Cinacalcet|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A First-in-human Study of Multiple Doses of Topically Administered PF-07295324 and PF-07259955
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: PF-07295324|DRUG: PF-07259955
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Proprioceptive Training Program Using an Uneven Terrain Treadmill for Patients With Ankle Instability
Status: UNKNOWN
Conditions: Instability; Ankle (Ligaments) (Old Injury)|Sprain of Ankle
Interventions: OTHER: Uneven Treadmill Intervention|OTHER: Standard of Care Physical Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Physical and Cognitive Industrial Workload
Status: UNKNOWN
Conditions: Work-Related Condition|Physical Stress|Mental Fatigue
Interventions: BEHAVIORAL: Industrial work|BEHAVIORAL: Physical load|BEHAVIORAL: Cognitive load
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Child Self-regulation: A Pilot Study on the Impact of Tuning in to Kids Parent Intervention
Status: ACTIVE_NOT_RECRUITING
Conditions: Parent and Child Emotional Intelligence and Child Self-regulation
Interventions: BEHAVIORAL: Tuning in to Kids
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Bovine Colostrum on Toxicity and Inflammatory Responses
Status: COMPLETED
Conditions: Acute Lymphoblastic Leukemia
Interventions: DIETARY_SUPPLEMENT: Bovine Colostrum|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Everolimus in Combination With DHAP in Patients With Relapsed or Refractory Hodgkin Lymphoma
Status: COMPLETED
Conditions: Hodgkin Lymphoma
Interventions: DRUG: DHAP|DRUG: Everolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Micronutrient Status in Children Aged 1-3 Years Consuming Their Habitual Diet With or Without Young Children's Milk
Status: TERMINATED
Conditions: Nutritional Status|Child Nutrition Sciences
Interventions: OTHER: Young children's milk (1-<3)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: 64Cu-SAR-bisPSMA and 67Cu-SAR-bisPSMA for Identification and Treatment of PSMA-expressing Metastatic Castrate Resistant Prostate Cancer (SECuRE)
Status: RECRUITING
Conditions: Prostatic Neoplasms, Castration-Resistant
Interventions: DRUG: 64Cu-SAR-bisPSMA|DRUG: 67Cu-SAR-bisPSMA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Effect of Fluvoxamine on the Pharmacokinetics of RO4917523 in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: Fluvoxamine|DRUG: RO4917523
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Database Study to Provide Information on Pregnancy and Infant Outcomes Among Women Exposed to QUVIVIQ (Daridorexant)
Status: ACTIVE_NOT_RECRUITING
Conditions: Insomnia Disorder
Interventions: DRUG: Daridorexant|DRUG: Non-orexin receptor antagonist insomnia medication|OTHER: No insomnia medication
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pharmacokinetic and Safety Studies of HRS-7535 in Subjects With Moderate Renal Insufficiency and Healthy Subjects
Status: NOT_YET_RECRUITING
Conditions: Type 2 Diabetes
Interventions: DRUG: HRS-7535 Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Panobinostat and Epirubicin in Treating Patients With Metastatic Malignant Solid Tumors
Status: COMPLETED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: epirubicin hydrochloride|DRUG: panobinostat|GENETIC: gene expression analysis|GENETIC: protein expression analysis|GENETIC: western blotting|OTHER: immunologic technique|OTHER: laboratory biomarker analysis|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Evaluate the Safety and Efficacy of "CITUS Dry Syrup" in Children With Perennial Allergic Rhinitis
Status: COMPLETED
Conditions: Perennial Allergic Rhinitis
Interventions: DRUG: CITUS Dry Syrup|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Treatment Therapy Approaches for the Treatment of High-Risk Multiple Myeloma, REACH Trial
Status: RECRUITING
Conditions: ISS Stage III Plasma Cell Myeloma|Multiple Myeloma
Interventions: PROCEDURE: Bone Marrow Aspiration and Biopsy|DRUG: Carfilzomib|PROCEDURE: Computed Tomography|BIOLOGICAL: Daratumumab|DRUG: Dexamethasone|DRUG: Lenalidomide|PROCEDURE: Magnetic Resonance Imaging|PROCEDURE: Positron Emission Tomography|PROCEDURE: Multigated Acquisition Scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Risk Model for Severe Rebound Pain After Lower Limb Orthopedic Surgery Involving Single-Shot Sciatic Nerve Blocks
Status: COMPLETED
Conditions: Orthopedic Procedures|Pain, Postoperative|Surgery|Nerve Block|Ambulatory Surgical Procedures|Pain
Interventions: OTHER: This is not an interventional study
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Microplegia on Transfusion Rates After Cardiac Surgery
Status: COMPLETED
Conditions: Aortic Valve Disease|Mitral Valve Disease
Interventions: DRUG: Cardioplegia Solution|DRUG: Microplegic Solution No. 1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Full-mouth Electronic Toothbrush vs. Conventional Electronic Toothbrush
Status: NOT_YET_RECRUITING
Conditions: Toothbrush|Gingivitis|Plaque
Interventions: DEVICE: FMET
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Montelukast Sodium Chewable Tablets 4mg and 5mg Under Fasting Condition
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Montelukast sodium chewable tablets 4 mg and 5 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Cranberry Juice on Endothelial Function
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DIETARY_SUPPLEMENT: Cranberry juice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Phase 1 Bioequivalence Study of Dapagliflozin/Sitagliptin FDC vs Loose Combination of Single Components
Status: COMPLETED
Conditions: Healthy Volunteers (Intended Indication: Type 2 Diabetes Mellitus)
Interventions: DRUG: Dapagliflozin/sitagliptin FDC|DRUG: Sitagliptin|DRUG: Dapagliflozin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of PRA-027 Administered to Healthy Japanese Females
Status: COMPLETED
Conditions: Uterine Leiomyomata (Fibroids)
Interventions: DRUG: PRA-027
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: COAST: Coiling of Aneurysms Smaller Than 5mm With Hypersoft® and Hydrogel Coils
Status: COMPLETED
Conditions: Small Intracranial Aneurysms
Interventions: OTHER: PHASE 1- HyperSoft® 3D and HyperSoft® Helical Coils|OTHER: PHASE 2 - HydroSoft® 3D and HydroSoft® Helical Coils
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Chronic Hepatitis C During Pregnancy With Sofosbuvir/Velpatasvir
Status: COMPLETED
Conditions: Hepatitis C, Chronic
Interventions: DRUG: Sofosbuvir-Velpatasvir Drug Combination
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tyrosine Kinase Inhibition to Treat Myeloid Hypereosinophilic Syndrome
Status: RECRUITING
Conditions: Eosinophilic Myeloid Neoplasm|Hypereosinophilic Syndrome
Interventions: DRUG: Imatinib|DRUG: Ruxolitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Proprietary Formulations of Oral Ketamine + Aspirin and Oral Ketamine Alone for Musculoskeletal Pain
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Aspirin and Ketamine|DRUG: Oral Ketamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Randomized Comparative Study of Outcome of Subscapularis Tear
Status: COMPLETED
Conditions: Rotator Cuff Syndrome
Interventions: PROCEDURE: arthroscopic repair|PROCEDURE: arthroscopic debridement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Low Antioxidant Diet in Controlling Cachexia in Patients With Oropharyngeal Cancer Receiving Chemotherapy and Radiation Therapy
Status: COMPLETED
Conditions: Cachexia|Head and Neck Cancer|Weight Changes
Interventions: OTHER: ADD|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Glial Tumors Electromagnetic Signature Study by MagnetoEncephaloGraphy (MEG) "CONDUCTOME"
Status: TERMINATED
Conditions: Cerebral Primitive Tumor With Chirurgical Indication
Interventions: OTHER: MEG and MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: 68Ga-NOTA-RM26 PET/CT for the Detection of Gastrointestinal Stromal Tumor
Status: UNKNOWN
Conditions: Gastrointestinal Stromal Tumors
Interventions: DRUG: 68Ga-NOTA-RM26
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Improved Speech Recognition Performance in Noise by Encoding Binaural Spatial Cues to the Cochlea Implant User
Status: WITHDRAWN
Conditions: Hearing Loss, Cochlear
Interventions: OTHER: S0N0|OTHER: S0N500|OTHER: S-500N500|OTHER: S0N1000|OTHER: S0Nuncorr
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of Subcutaneous Mircera for the Maintenance Treatment of Dialysis Patients With Chronic Renal Anemia.
Status: COMPLETED
Conditions: Anemia
Interventions: DRUG: methoxy polyethylene glycol-epoetin beta [Mircera]|DRUG: Epoetin alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Evaluate the Sun Protection Factor (SPF) of Three Sunscreen Products
Status: COMPLETED
Conditions: Sunscreening Agents
Interventions: DRUG: CAP UnScented|DRUG: CAP Herbal Mint|DRUG: CAP Mountain Berry|DRUG: SPF Standard Sunscreen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I Trial of Docetaxel and Low-Dose Fractionated Radiation in the Treatment of Metastatic or Recurrent NSCLC
Status: TERMINATED
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: Docetaxel|RADIATION: Radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial of HR18034 for Postoperative Analgesia in Subjects Undergoing Hemorrhoidectomy.
Status: COMPLETED
Conditions: Postsurgical Pain Management
Interventions: DRUG: HR18034|DRUG: HR18034|DRUG: HR18034|DRUG: ropivacaine HCl.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Rucaparib in Combination With Nivolumab in Patients With Selected Solid Tumors (ARIES)
Status: TERMINATED
Conditions: Epithelial Ovarian Cancer|Fallopian Tube Cancer|Primary Peritoneal Carcinoma|High Grade Serous Carcinoma|Endometrioid Adenocarcinoma
Interventions: DRUG: Rucaparib|DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Tibilone on Bone Density, Menopause Symptoms and Breast Density in Women After Prophylactic Oophorectomy
Status: COMPLETED
Conditions: Menopause|Postmenopausal Bone Loss|Breast Cancer
Interventions: DRUG: Tibolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Adjunctive Cannabidiol Oral Solution (GWP42003-P) in Children With Tuberous Sclerosis Complex (TSC), Dravet Syndrome (DS), or Lennox-Gastaut Syndrome (LGS) Who Experience Inadequately-controlled Seizures
Status: RECRUITING
Conditions: Seizure in Participants With Tuberous Sclerosis Complex|Seizure in Participants With Dravet Syndrome|Seizure in Participants With Lennox-Gastaut Syndrome
Interventions: DRUG: GWP42003-P
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Colposcopy and High Resolution Anoscopy in Screening For Anal Dysplasia in Patients With Cervical, Vaginal, or Vulvar Dysplasia or Cancer
Status: WITHDRAWN
Conditions: Cervical Intraepithelial Neoplasia Grade 1|Cervical Intraepithelial Neoplasia Grade 2|Cervical Intraepithelial Neoplasia Grade 3|Recurrent Cervical Cancer|Recurrent Vaginal Cancer|Recurrent Vulvar Cancer|Stage 0 Cervical Cancer|Stage 0 Vaginal Cancer|Stage 0 Vulvar Cancer|Stage I Vaginal Cancer|Stage I Vulvar Cancer|Stage IA Cervical Cancer|Stage IB Cervical Cancer|Stage II Vaginal Cancer|Stage II Vulvar Cancer|Stage IIA Cervical Cancer|Stage IIB Cervical Cancer|Stage III Cervical Cancer|Stage III Vaginal Cancer|Stage III Vulvar Cancer|Stage IV Vulvar Cancer|Stage IVA Cervical Cancer|Stage IVA Vaginal Cancer|Stage IVB Cervical Cancer|Stage IVB Vaginal Cancer
Interventions: PROCEDURE: colposcopy|OTHER: cervical Papanicolaou test|PROCEDURE: screening method|PROCEDURE: screening method
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Nutrient and Immunity Status in Children Aged 3-5 Years Consuming Their Habitual Diet With or Without Fortified Milk
Status: COMPLETED
Conditions: Nutritional Status|Child Nutrition Sciences|Toddlers
Interventions: OTHER: Fortified milk
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Effect of Different Low-Level Tragus Stimulation Parameters On Autonomic Nervous System Function
Status: RECRUITING
Conditions: Atrial Fibrillation|Heart Failure, Diastolic
Interventions: DEVICE: Parasym
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Innovation-TiFP4-C101: A Study to Evaluate the Pharmacokinetics of TMC114 and TMC41629 After a Single Oral Dose of 2 Controlled-release Coformulations as Compared to an Immediate-release Coformulation of TMC114/TMC41629
Status: COMPLETED
Conditions: HIV-I
Interventions: DRUG: TMC114; TMC41629
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Role of Transdermal CO2 in MDA Level in Patient Underwent Abdominal Aortic Temporary Cross Clamp
Status: UNKNOWN
Conditions: Placenta Accreta
Interventions: DRUG: D'Oxyva
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Blood Pressure Monitoring in Postpartum Women at Risk of Hypertension
Status: UNKNOWN
Conditions: Hypertension in Pregnancy|Preeclampsia|Gestational Hypertension|Chronic Hypertension With Pre-Eclampsia|Hypertension Complicating Pregnancy, Childbirth, and the Puerperium
Interventions: BEHAVIORAL: Remote blood pressure monitoring|BEHAVIORAL: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Real-World Evidence of Duration of Effect of Adhansia XR (Extended-Release) for Treatment of Attention-Deficit/Hyperactivity Disorder (ADHD)
Status: TERMINATED
Conditions: Attention-Deficit/Hyperactivity Disorder
Interventions: DRUG: Adhansia XR|DRUG: Concerta
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Intravitreal Implantation of NT-503-3 Encapsulated Cell Technology (ECT) for the Treatment of Recurrent Choroidal Neovascularization (CNV) Secondary to Age-related Macular Degeneration (AMD)
Status: TERMINATED
Conditions: Macular Degeneration
Interventions: DRUG: NT-503-3 ECT implantation|DRUG: Eylea® injected intravitreally administered every 8 weeks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II Dose-ranging Study of APD421 in PONV
Status: COMPLETED
Conditions: Postoperative Nausea and Vomiting
Interventions: DRUG: APD421|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Cognitive Strategy Training on Daily Function in People With Subjective Cognitive Decline
Status: UNKNOWN
Conditions: Subjective Cognitive Decline
Interventions: BEHAVIORAL: Cognitive strategy training|BEHAVIORAL: group interactive game
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pemetrexed Disodium, Gemcitabine, and Bevacizumab in Treating Patients With Stage IIIB or Stage IV Non-Small Cell Lung Cancer
Status: TERMINATED
Conditions: Lung Cancer
Interventions: BIOLOGICAL: bevacizumab|DRUG: gemcitabine hydrochloride|DRUG: pemetrexed disodium
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Small Versus Large Epidural Needles on Postdural Puncture Headache Study
Status: COMPLETED
Conditions: Post-Dural Puncture Headache
Interventions: DEVICE: 19g Tuohy-type epidural needle, 23g catheter|DEVICE: => 18g Tuohy-type needle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of Tirzepatide (LY3298176) in Participants With Overweight or Obesity and Chronic Kidney Disease With or Without Type 2 Diabetes
Status: RECRUITING
Conditions: Overweight|Obesity|Chronic Kidney Disease|Type 2 Diabetes|T2D
Interventions: DRUG: Tirzepatide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Chlorhexidine/Thymol Varnish on Partial Denture Patient
Status: WITHDRAWN
Conditions: Periodontal Disease|Caries
Interventions: DRUG: Chlorhexidine/Thymol varnish
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study Comparing Bifeprunox to Risperidone in Treatment of Outpatients With Schizophrenia With Weight as Primary Endpoint
Status: TERMINATED
Conditions: Schizophrenia
Interventions: DRUG: bifeprunox|DRUG: risperidone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Art Therapy qEEG Study for Service Members With a Traumatic Brain Injury and Posttraumatic Stress Symptoms
Status: COMPLETED
Conditions: Post-Traumatic Headache|PTSD|TBI|TBI (Traumatic Brain Injury)|MTBI - Mild Traumatic Brain Injury|Posttraumatic Stress Disorder|Posttraumatic Stress Disorder, Delayed Onset|Sleep Disturbance|Nightmare|Nightmares, REM-Sleep Type|Headache|Irritable Mood|Anger|Eating Disorders|Combat and Operational Stress Reaction|Combat Stress Disorders|Military Operations|Military Activity|Military Family
Interventions: BEHAVIORAL: Art Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stress-Induced Inflammation and Reward Processing
Status: COMPLETED
Conditions: Stress, Psychological
Interventions: BEHAVIORAL: Stress; Trier Social Stress Task|BEHAVIORAL: Placebo Trier Social Stress Task
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Open-Label Study Evaluating Dasatinib Therapy Discontinuation in Patients With Chronic Phase Chronic Myeloid Leukemia With Stable Complete Molecular Response
Status: COMPLETED
Conditions: Chronic Phase Chronic Myeloid Leukemia
Interventions: DRUG: Dasatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER