pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Study to Assess the Effect of Multistrain Probiotic on the Immune Response to the Influenza Vaccination
Status: COMPLETED
Conditions: Influenza
Interventions: DIETARY_SUPPLEMENT: Multistrain probiotic|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acalabrutinib for the Treatment of Relapsed or Refractory Autoimmune Hemolytic Anemia in Patients With Chronic Lymphocytic Leukemia
Status: ACTIVE_NOT_RECRUITING
Conditions: Autoimmune Hemolytic Anemia|Chronic Lymphocytic Leukemia|Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma|Warm Antibody Autoimmune Hemolytic Anemia
Interventions: DRUG: Acalabrutinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Peripheral Magnetic Stimulation to Treat Patient With Post-stroke Shoulder-hand Syndrome
Status: UNKNOWN
Conditions: Reflex Sympathetic Dystrophy of Upper Limb|Stroke
Interventions: DEVICE: peripheral magnetic stimulation|OTHER: physical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use of a Rapid Test for Gonorrhea & Chlamydia for Women Presenting With Possible Sexually Transmitted Infections
Status: TERMINATED
Conditions: Sexually Transmitted Infection|Gonorrhea Female|Chlamydia Females
Interventions: DEVICE: Cepheid Xpert CT/NG Rapid Turnaround Test|DEVICE: Polymerase chain reaction (PCR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Improving Transplant Options of Highly Sensitized Recipients Using IGIV-C, 10%
Status: TERMINATED
Conditions: Kidney Failure, Chronic
Interventions: BIOLOGICAL: Immune Globulin Intravenous (Human), 10%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose Escalation and Dose Expansion Study of MDX2001 in Patients With Advanced Solid Tumors
Status: RECRUITING
Conditions: Biliary Tract Cancer|Breast Cancer|Cervical Cancer|Colon Cancer|Endometrial Cancer|Esophageal Cancer|Gastric Cancer|GastroEsophageal Cancer|Head and Neck Cancer|Hepatocellular Cancer|Non-small Cell Lung Cancer|Pancreatic Cancer|Prostate Cancer|Rectal Cancer|Renal Cancer|Thyroid Cancer
Interventions: DRUG: MDX2001
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Whole Body Vibration Therapy in Children With Juvenile Idiopathic Arthritis
Status: WITHDRAWN
Conditions: Juvenile Idiopathic Arthritis
Interventions: DEVICE: Galileo (whole body vibration (WBV) therapy)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Look at the Safety of NNC0363-0845 in Healthy People and People With Type 1 Diabetes
Status: COMPLETED
Conditions: Healthy Volunteers|Diabetes Mellitus, Type 1
Interventions: DRUG: NNC0363-0845|DRUG: Placebo (NNC0363-0845)|DRUG: Insulin degludec
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Fixed Bearing vs Mobile Bearing Cruciate Retaining TKA
Status: COMPLETED
Conditions: Osteoarthritis|Rheumatoid Arthritis|Post-traumatic Arthritis|Juvenile Rheumatoid Arthritis|Avascular Necrosis of Bone
Interventions: DEVICE: Total Knee Replacement|DEVICE: Total knee replacement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Laser Acupuncture for Idiopathic Bell's Palsy
Status: COMPLETED
Conditions: Bell's Palsy
Interventions: DEVICE: Laser acupuncture|DRUG: Steroids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Rituximab Monotherapy on Children With New-onset Nephrotic Syndrome: A Randomized Controlled Trial
Status: RECRUITING
Conditions: Nephrotic Syndrome in Children|Rituximab
Interventions: DRUG: Rituximab|DRUG: Steroid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Nelfinavir Plus Saquinavir Plus Delavirdine or 3TC/ZDV Versus Nelfinavir Plus 3TC/ZDV in HIV-Infected Patients
Status: WITHDRAWN
Conditions: HIV Infections
Interventions: DRUG: Lamivudine/Zidovudine|DRUG: Nelfinavir mesylate|DRUG: Saquinavir|DRUG: Delavirdine mesylate
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: [S,S]-Reboxetine Long Term Safety Study In Chronic Painful Diabetic Peripheral Neuropathy.
Status: TERMINATED
Conditions: Pain
Interventions: DRUG: [S,S]-Reboxetine|DRUG: Any
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Controlled Trial of Chinese Herbal Medicine to Treat Allergic Rhinitis
Status: COMPLETED
Conditions: Allergic Rhinitis
Interventions: DRUG: Cure-Allergic Rhinitis Syrup|DRUG: Yu-ping-fung San|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 42-Day Repeat Oral Dose Study of AKB-6548 in Participants With Chronic Kidney Disease and Anemia
Status: COMPLETED
Conditions: Anemia|Kidney Disease
Interventions: DRUG: AKB-6548|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: DualStim Therapy With or Without Umbilical Cord Derived Wharton's Jelly for Erectile Dysfunction
Status: NOT_YET_RECRUITING
Conditions: Erectile Dysfunction
Interventions: DEVICE: DualStim Therapy|BIOLOGICAL: Umbilical cord-derived Wharton's Jelly|OTHER: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Phase I Trial of TGFB2-Antisense-GMCSF Gene Modified Autologous Tumor Cell (TAG) Vaccine for Advanced Cancer
Status: TERMINATED
Conditions: Carcinoma, Advanced Metastatic
Interventions: BIOLOGICAL: TGFβ2 Antisense-GMCSF Gene Modified Autologous Tumor Cell (TAG) Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Continuing vs Intermittent Trabectedin in Patients With Advanced Soft Tissue Sarcoma
Status: COMPLETED
Conditions: Soft Tissue Sarcoma|Uterine Sarcoma
Interventions: DRUG: Trabectedin|OTHER: Drug: holiday
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of a Personalized Weaning Strategy on Weaning Success
Status: RECRUITING
Conditions: Weaning|Mechanical Ventilation|Intubation
Interventions: OTHER: Standard SBT|OTHER: SBT with T-piece or PSV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Planned Semi-Elective Lung Transplantation Using 10C Cold Static Preservation
Status: COMPLETED
Conditions: Pulmonary Disease
Interventions: PROCEDURE: Delayed Lung Transplantation|PROCEDURE: Conventional Lung Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exclusion of Venous Thrombo-Embolism With a New Clinical Decision Support
Status: RECRUITING
Conditions: Venous Thromboembolism|Pulmonary Embolism|Deep Vein Thrombosis
Interventions: DIAGNOSTIC_TEST: Routine Assays on fresh plasma|DIAGNOSTIC_TEST: New Clinical Decision Support on fresh plasma|DIAGNOSTIC_TEST: New Clinical Decision Support on frozen plasma
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Arming Health: Can Breaking up Restful Sitting Time With Upper Body Contractile Activity Regulate Metabolic Health.
Status: COMPLETED
Conditions: Diabetes
Interventions: OTHER: Prolonged Sitting|OTHER: Light arm ergometry breaks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparing Sports Bra Design in Full Busted Women
Status: COMPLETED
Conditions: Breast Pain|Mastalgia|Back Pain|Back Strain|Back Pain, Low|Neck Pain|Chest Pain|Activity, Motor|Aging Well|Weight, Body|Body Image
Interventions: OTHER: Conventional bra|OTHER: Bounceless bra|OTHER: Shefit bra
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Diode Laser and Green Indocyanine in the Non-surgical Treatment of Periodontitis
Status: COMPLETED
Conditions: Periodontitis
Interventions: PROCEDURE: FMUD + DLIG|PROCEDURE: FMUD + ST
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Safety, Tolerability, and Pharmacokinetics of E2730
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DRUG: E2730|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study on the Immune Response and Safety of a Vaccine Against Respiratory Syncytial Virus (RSV) When Given Alone and Together With a COVID-19 mRNA Vaccine in Adults Aged 50 Years and Above
Status: ACTIVE_NOT_RECRUITING
Conditions: Respiratory Syncytial Virus Infections
Interventions: BIOLOGICAL: RSVPreF3 OA investigational vaccine|BIOLOGICAL: COVID-19 mRNA vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of BNC210 in Elderly Patients With Agitation
Status: COMPLETED
Conditions: Agitation in the Elderly
Interventions: DRUG: BNC210|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Resveratrol Supplementation on Cognition, Cerebral Blood Flow, Microbiota and Systemic Inflammation.
Status: COMPLETED
Conditions: Cognitive Function and Mood|Cerebral Blood Flow|Systemic Inflammation|Gut Microbiota|Overweight and Obesity
Interventions: DIETARY_SUPPLEMENT: Resveratrol|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Effect of Soft Tissue Augmentation With an Acellular Dermal Matrix in Marginal Bone Levels Around Implants
Status: ACTIVE_NOT_RECRUITING
Conditions: Dental Implant Failure Nos
Interventions: DEVICE: NovoMatrix|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: LUME-Lung 1: BIBF 1120 Plus Docetaxel as Compared to Placebo Plus Docetaxel in 2nd Line Non Small Cell Lung Cancer
Status: COMPLETED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: placebo plus docetaxel|DRUG: BIBF 1120 plus docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Cancer: Thriving and Surviving Online Workshop and Study for Cancer Survivors
Status: COMPLETED
Conditions: Blood Cancer|Breast Cancer|Prostatic Neoplasms|Colorectal Neoplasms|Neoplasms
Interventions: BEHAVIORAL: Cancer: Thriving and Surviving Online Workshop
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A New Scoring System Improves Diagnostic Accuracy of Intestinal Dysganglionosis --a Prospective Study
Status: UNKNOWN
Conditions: Hirschsprung Disease
Interventions: DRUG: high dose lactulose|BEHAVIORAL: conservative treatment|DRUG: paraffin oil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Deep Brain Stimulation of the nbM to Treat Mild Cognitive Impairment in Parkinson's Disease
Status: TERMINATED
Conditions: Parkinson's Disease|Mild Cognitive Impairment
Interventions: DEVICE: stimulation ON|DEVICE: stimulation OFF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase II Randomized Controlled Trial to Determine the Efficacy of an auGmented reAlity gaMe in pediatrIc caNcer Patients Who Are Opioid Naïve Undergoing Surgery to Reduce Postoperative Opioid Use (GAMING-ON Study)
Status: RECRUITING
Conditions: Pediatric ALL|Cancer
Interventions: OTHER: IPAD|OTHER: Augmented Reality
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Efficacy Study of Sebelipase Alfa in Participants With Lysosomal Acid Lipase Deficiency
Status: COMPLETED
Conditions: Lysosomal Acid Lipase Deficiency
Interventions: DRUG: Sebelipase Alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effect of Mirabegron + Solifenacin in Overactive Bladder Patients
Status: COMPLETED
Conditions: Overactive Bladder
Interventions: DRUG: mirabegron|DRUG: solifenacin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Wetsuit and Life Jacket Induced Effects on Spirometry and VO2 in Windsurfers
Status: COMPLETED
Conditions: Ventilation|Exercise
Interventions: DIAGNOSTIC_TEST: resting standard spirometry|DIAGNOSTIC_TEST: maximum exercise testing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Clinical Study of Raloxifene and Strontium Ranelate in Postmenopausal Osteoporosis
Status: COMPLETED
Conditions: Postmenopausal Osteoporosis|Compliance
Interventions: DRUG: Raloxifene|DRUG: Strontium ranelate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Nepafenac on Post-operative Macular Swelling Following Uncomplicated Cataract Surgery
Status: COMPLETED
Conditions: Cystoid Macular Edema
Interventions: DRUG: Standard Care|DRUG: nepafenac
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparison of Video Laryngoscopy and Direct Laryngoscopy for Nasotracheal Intubation During Pediatric Dental Surgery
Status: COMPLETED
Conditions: Airway Complication of Anesthesia|Peroperative Complication|Intraoperative Hypertension|Tachycardia, Sinus|Desaturation of Blood
Interventions: DEVICE: Laryngoscopy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Impact of Egg Consumption on Carotenoid and Vitamin D Bioavailability in Pre- and Post-menopausal Women
Status: COMPLETED
Conditions: Menopause
Interventions: BEHAVIORAL: Egg consumption|BEHAVIORAL: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Ga-68 PSMA-11 PET/CT in Patients With Biochemical Recurrence of Prostate Cancer: Digital PET/CT Versus Analog PET/CT
Status: UNKNOWN
Conditions: Prostate Cancer
Interventions: DIAGNOSTIC_TEST: Ga-68 PSMA-11 PET/CT imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Anesthetic Blockades and Migraine
Status: COMPLETED
Conditions: Chronic Migraine|Pain
Interventions: DRUG: Anesthetic blockades with bupivacaine|DRUG: Isotonic saline injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An Open-label, Phase 2 Study to Assess the Efficacy and Safety of Nemolizumab in Subjects With Systemic Sclerosis
Status: ACTIVE_NOT_RECRUITING
Conditions: Systemic Sclerosis
Interventions: DRUG: nemolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dexamethasone and Ketamine on Change of Postoperative Mood
Status: COMPLETED
Conditions: Depressive Symptoms
Interventions: DRUG: Ketamine Hydrochloride, dexamethasone, and combination of two drugs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Antiviral Activity, Clinical Outcomes, Safety, Tolerability, and Pharmacokinetics of Oral Lumicitabine Regimens in Hospitalized Adult Participants Infected With Human Metapneumovirus
Status: WITHDRAWN
Conditions: Metapneumovirus
Interventions: DRUG: Lumicitabine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Intravenous Mircera for the Treatment of Anemia in Dialysis Patients.
Status: COMPLETED
Conditions: Anemia
Interventions: DRUG: methoxy polyethylene glycol-epoetin beta [Mircera]
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Open-label, Three-period, Partial-replicate Design Study to Evaluate the Inter- and Intrasubject Variability of the Avatrombopag To-be-marketed Formulation Administered as Single Doses of 40 mg to Healthy Subjects Receiving a Low-fat Meal
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Avatrombopag maleate 40 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating The Effects Of Single Oral Doses Of NSA-789 On Auditory P50 Suppression In Schizophrenic Patients
Status: WITHDRAWN
Conditions: Schizophrenia
Interventions: DRUG: NSA-789 at 2 different doses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Azithromycin Based Therapy for Induction of Remission in Active Pediatric Crohn's Disease
Status: COMPLETED
Conditions: Crohn's Disease
Interventions: DRUG: Azithromycin + Metronidazole|DRUG: Metronidazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Novel Wrist Sensor System to Promote Hemiparetic Arm Use in Home Daily Life of Chronic Stroke Survivors
Status: NOT_YET_RECRUITING
Conditions: Stroke|Stroke Sequelae|Hemiparesis;Poststroke/CVA
Interventions: COMBINATION_PRODUCT: StrokeWear Motor and Behavioral Intervention|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Remote Hypertension Management for Black Patients
Status: NOT_YET_RECRUITING
Conditions: Uncontrolled Hypertension
Interventions: BEHAVIORAL: RHYTHM (Remote Hypertension Tracking Help Management)|BEHAVIORAL: Enhanced usual care (UC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Use of FlexHD as Post Trapeziectomy Spacer
Status: COMPLETED
Conditions: Osteoarthrosis of the Carpometacarpal Joint of the Thumb
Interventions: PROCEDURE: Arthroplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Can Epidermal Growth Factor Receptor Improve the Postoperative Survivorship for Inoperable Non-small Cell Lung Cancer With Spinal Metastasis ?
Status: COMPLETED
Conditions: Is Targeted Therapy Increasing Survival Inoperable Nonsmall Cell Lung Cancer With Spinal Metastasis ?
Interventions: DRUG: Gefitinib
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Intraurethral/Intravaginal 2940 nm Erbium Laser Treatment For Stress Urinary Incontinence
Status: UNKNOWN
Conditions: Stress Urinary Incontinence
Interventions: DEVICE: Sham Fotona SP Dynamis|DEVICE: Intravaginal Fotona SP Dynamis|DEVICE: Intraurethral Fotona SP Dynamis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Asses the Impact of Early Starting Erythropoetin in the Reduction of Transfusions Blood in Childrens
Status: NOT_YET_RECRUITING
Conditions: Anemia|Neoplasms|Chemotherapeutic-Induced Anemia
Interventions: BIOLOGICAL: Erythropoietin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Implantable MyoElectric Sensors (IMES) for Prosthetic Control in Transhumeral Amputees
Status: COMPLETED
Conditions: Amputation
Interventions: DEVICE: Implantation of IMES sensors
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: A Study to Determine Safety and Tolerability of Enzalutamide (MDV3100) in Combination With Abiraterone Acetate in Bone Metastatic Castration-Resistant Prostate Cancer Patients
Status: COMPLETED
Conditions: Metastatic Castration-Resistant Prostate Cancer
Interventions: DRUG: enzalutamide|DRUG: abiraterone acetate|DRUG: prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasound Guided Microwave Ablation of Splenomegaly in Children
Status: RECRUITING
Conditions: Splenomegaly; Congestive, Chronic|Panhematopenia; Splenic|Portal Hypertension
Interventions: PROCEDURE: Microwave ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PhIb BKM120 or BEZ235+Endocrine Treatment in Post-Menopausal Patients With Hormone Receptor + Metastatic Breast Cancer
Status: COMPLETED
Conditions: Metastatic Breast Cancer
Interventions: DRUG: BEZ235|DRUG: BKM 120|DRUG: Letrozole|DRUG: BKM120
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Extracorporeal Shock Wave Therapy (ESWT) for the Treatment of Spasticity in Persons With Spinal Cord Injury
Status: COMPLETED
Conditions: Spinal Cord Injury|Spasticity
Interventions: DEVICE: Duolith® SD 1 "T-Top" (Storz Medical AG, Switzerland)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of E7820 in People With Bone Marrow (Myeloid) Cancers
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Myeloid Leukemia|Myelodysplastic Syndromes|Chronic Myelomonocytic Leukemia
Interventions: DRUG: E7820
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Addition of Whole Grains to the Diets of Adults: A Study of Digestive Health and Natural Defenses
Status: COMPLETED
Conditions: Digestive Health and Immune Function
Interventions: OTHER: Whole grains|OTHER: Refined grains
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Randomized Controlled Study of the Effectiveness of IV Fluid Infusion in Patients With Acute Ischemic Stroke (IVIS)
Status: TERMINATED
Conditions: Ischemic Stroke
Interventions: DRUG: 0.9% NaCl solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Gum Chewing on Recovery of Bowel Function Following Benign Gynecologic Surgery
Status: UNKNOWN
Conditions: Recovery of Bowel Function, Due to Gum Chewing
Interventions: BEHAVIORAL: Gum chewing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Gemcitabine With or Without Bevacizumab in Treating Patients With Locally Advanced or Metastatic Pancreatic Cancer
Status: COMPLETED
Conditions: Adenocarcinoma of the Pancreas|Recurrent Pancreatic Cancer|Stage II Pancreatic Cancer|Stage III Pancreatic Cancer|Stage IV Pancreatic Cancer
Interventions: DRUG: gemcitabine hydrochloride|BIOLOGICAL: bevacizumab|OTHER: placebo|OTHER: laboratory biomarker analysis|OTHER: pharmacogenomic studies|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Physiotherapy-led Outpatient Clinic for Patients With Spondyloarthritis
Status: COMPLETED
Conditions: Spondylarthritis|Spondylitis, Ankylosing|Spondylarthropathies|Sacroiliitis|Arthritis, Psoriatic
Interventions: OTHER: Physiotherapy follow-up
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Azithromycin + Artesunate v Artemether-lumefantrine in Uncomplicated Malaria.
Status: COMPLETED
Conditions: Malaria
Interventions: DRUG: azithromycin + artesunate|DRUG: artemether-lumefantrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hs-cTn - Optimizing the Diagnosis of Acute Myocardial Infarction/Injury in Women
Status: UNKNOWN
Conditions: Myocardial Infarction|Sex Differences|High Sensitivity Troponin
Interventions: DIAGNOSTIC_TEST: Introduction of a lower female hs-cTn threshold
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Ketamine Versus Dexmedetomidine in Supraclavicular Brachial Plexus Block
Status: COMPLETED
Conditions: Supraclavicular Brachial Plexus Block
Interventions: DRUG: Supraclavicular Brachial Plexus Block with bupivacaine|DRUG: Supraclavicular Brachial Plexus Block with Ketamine|DRUG: Supraclavicular Brachial Plexus Block with Dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Decision Biological Biomarker and Prognosis Prediction of Hepatocellular Carcinoma by Deep Learning
Status: RECRUITING
Conditions: Hepatocellular Carcinoma|Contrast-enhanced Ultrasound|Prognosis|Surgery|Ablation
Interventions: PROCEDURE: Surgery|PROCEDURE: Ablation (Microwave ablation or Radiofrequency ablation)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Modulation of Microbial Composition in Ileostomy Patients
Status: COMPLETED
Conditions: Ileostomy - Stoma
Interventions: DIETARY_SUPPLEMENT: Probiotic 1|DIETARY_SUPPLEMENT: Probiotic 2|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Intracardiac Versus Transesophageal Echocardiographic Guidance for Left Atrial Appendage Occlusion
Status: ACTIVE_NOT_RECRUITING
Conditions: Left Atrial Appendage Closure
Interventions: OTHER: Intracardiac Echocardiography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effects of Glutamine on GLP-1 and Insulin Secretion in Man
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: Sitagliptin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: (Cost) Effectiveness Study of Exercise Therapy in Patients With Peripheral Arterial Disease
Status: UNKNOWN
Conditions: Intermittent Claudication
Interventions: PROCEDURE: Exercise therapy|DEVICE: Accelerometer (PAM; Personal Activity Monitor)|PROCEDURE: Oral Exercise Therapy advise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Second Line Treatment With Nal-IRI and S1 in Pancreatic Cancer
Status: UNKNOWN
Conditions: Metastatic Pancreatic Cancer
Interventions: DRUG: S1 + Nal-IRI|DRUG: Nal-IRI+Leucovorin+5-FU
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Interpersonal Psychotherapy (IPT) for Men and Women Prisoners With Major Depression
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: BEHAVIORAL: Group IPT for Depression + TAU
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Hand Ball Used During Venous Blood Collection on Pain and Fear Level in Children
Status: UNKNOWN
Conditions: Nurse's Role
Interventions: OTHER: The group holding the serrated ball in the hand on the extremity from which venous blood will be taken|OTHER: The group holding the serrated ball in the hand on the opposite side of the extremity from which venous blood will be taken.|OTHER: The group holding a smooth ball in the hand on the extremity from which venous blood will be taken|OTHER: The group holding a smooth ball in the hand opposite the extremity from which venous blood will be taken.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Sildenafil Citrate in Early Unexplained Recurrent Pregnancy Loss
Status: COMPLETED
Conditions: Miscarriage, Recurrent
Interventions: DRUG: Sildenafil Citrate|DRUG: Folic Acid|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Oral Analgesic Utilization for CHildhood Musculoskeletal Injuries
Status: COMPLETED
Conditions: Musculoskeletal Injury
Interventions: DRUG: oral morphine and oral ibuprofen|DRUG: Oral morphine|DRUG: Oral ibuprofen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Taxane/Carboplatin +/- Cetuximab as First-Line Treatment for Patients With Advanced/Metastatic Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Non-Small-Cell Lung Carcinoma
Interventions: DRUG: Paclitaxel (Taxane)|DRUG: Docetaxel (Taxane)|DRUG: Carboplatin|DRUG: Cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Glucosamine and Chondroitin Effects
Status: COMPLETED
Conditions: Inflammation
Interventions: DIETARY_SUPPLEMENT: Glucosamine and Chondroitin|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Study of the Cardiometabolic Effects of Obesity Pharmacotherapy
Status: UNKNOWN
Conditions: Obesity|Blood Pressure
Interventions: DRUG: Liraglutide 6 MG/ML [Saxenda]|DRUG: Naltrexone-Bupropion Combination
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Retrospective Analysis on Large Incisional Hernia in High Risk Patients
Status: COMPLETED
Conditions: Incisional Hernia|Large Incisional Hernia
Interventions: PROCEDURE: hernioplastic and insertion of FLaPp® composite mesh
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aesthetic Outcomes of Single Tooth Implant Using Metal Ceramic Restorations With Either Zirconia or Titanium Abutments
Status: COMPLETED
Conditions: Thick Gingival Margin to Tooth Restoration
Interventions: DEVICE: SPI®ART|DEVICE: SPI®EASY
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Daily Interruption of Continuous Sedation on Delirium, Sleep Perception in Intensive Care Unit (ICU) Patients
Status: COMPLETED
Conditions: Delirium|Sleep Perception
Interventions: PROCEDURE: Normal continuous sedation|OTHER: Daily interruption of continuous sedation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Patient Outcomes in Unattended and In- Lab Polysomnography
Status: SUSPENDED
Conditions: Sleep Apnea|Hypersomnia
Interventions: DIAGNOSTIC_TEST: Attended Polysomnography in the Lab|DIAGNOSTIC_TEST: Unattended Polysomnography in the Home
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effectiveness of Laser Therapy on Proximal Hamstring Tendinopathy
Status: COMPLETED
Conditions: Tendinopathy|Lasers
Interventions: RADIATION: Laser Therapy|OTHER: Ultrasound + Moist Heat pack + Exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Efficacy and the Tolerance of the Medical Device V063B-DP3003 on Dentin Hypersensitivity During Teeth Whitening
Status: COMPLETED
Conditions: Tooth Whitening
Interventions: DEVICE: Elgydium Clinic Sensileave Gel (V063B - DP3003)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of Instructed Dental Flossing on Interdental Gingival Bleeding: A Randomized Controlled Clinical Trial
Status: COMPLETED
Conditions: Gingival Inflammation
Interventions: OTHER: Flossing technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Assessment of the Impact of Probiotics on Biofilm Formation on Removable Acrylic Dentures
Status: COMPLETED
Conditions: Mandibular Prosthesis User
Interventions: DRUG: PIP toothbrush cleaner® (Chrisal, Lommel, Belgium).|DRUG: Corega Tabs Anti-bacteria®|OTHER: Water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Using a Computer-assisted Prescription to Decrease Inappropriate Use of Plain Abdominal Radiography in Emergency Department
Status: UNKNOWN
Conditions: Plain Abdominal Radiography
Interventions: OTHER: Computer-assisted prescription
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Evaluate Safety/Tolerability Intra-Arterial Temozolomide in Patients w/Extremity Melanoma by Isolated Limb Infusion
Status: COMPLETED
Conditions: Melanoma
Interventions: DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nelfinavir Mesylate, Radiation Therapy, and Temozolomide in Treating Patients With Glioblastoma Multiforme
Status: TERMINATED
Conditions: Brain and Central Nervous System Tumors
Interventions: DRUG: nelfinavir mesylate|DRUG: temozolomide|PROCEDURE: adjuvant therapy|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Different Obturation Techniques on Postobturation Pain in Single-Visit Root Canal Treatment
Status: RECRUITING
Conditions: Postoperative Pain
Interventions: PROCEDURE: Single obturation technique (Bioceramic Sealer)|PROCEDURE: lateral condensation technique (Bioceramic Sealer)|PROCEDURE: Warm Vertical condensation technique (Bioceramic Sealer)|PROCEDURE: lateral condensation technique (AH Plus Sealer)|PROCEDURE: Warm Vertical condensation technique (AH plus Sealer)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: HemaTrate™ in the Treatment of Critical Limb Ischemia
Status: TERMINATED
Conditions: Critical Limb Ischemia|Ischemia
Interventions: DEVICE: HemaTrate™ Blood Filtration system|OTHER: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Functional and Nutritional Plant-based Mixed Protein Study (FuN Protein Study)
Status: RECRUITING
Conditions: Nutrition, Healthy
Interventions: OTHER: Investigational meal 1 - Commercial animal-based protein foods [Siew mai (6 pieces) and Ngoh hiang (2 pieces)]|OTHER: Investigational meal 2- Commercial animal-based protein foods [Gyoza (11 pieces) and Luncheon meat (5 pieces)]|OTHER: Investigational meal 3- Formulated plant-based protein foods [Siew mai (6 pieces) and Ngoh hiang (1 piece cut into 2)]|OTHER: Investigational meal 4- Formulated plant-based protein foods [Gyoza (11 pieces) and Luncheon meat (5 pieces)]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Thrombus Aspiration in STEMI Patients With High Thrombus Burden
Status: RECRUITING
Conditions: ST-segment Elevation Myocardial Infarction (STEMI)
Interventions: PROCEDURE: Thrombus aspiration|PROCEDURE: PCI Alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic and Safety Study of Naltrexone Release From Subcutaneous BICX104 Pellets Compared to Vivitrol Injections
Status: COMPLETED
Conditions: Opioid-use Disorder
Interventions: DRUG: BICX104|DRUG: Vivitrol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Indian POLYCAP Study (TIPS)
Status: COMPLETED
Conditions: Cardiovascular Diseases
Interventions: DRUG: Thiazides|DRUG: Ramipril with Thiazide|DRUG: Thiazide plus atenolol|DRUG: Ramipril plus atenolol|DRUG: Ramipril plus atenolol plus thiazide|DRUG: POLYCAP|DRUG: Thiazide + Ramipril+Atenolol+Aspirin|DRUG: Simvastatin|DRUG: aspirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: AdvanTIG-203: Anti-PD-1 Monoclonal Antibody Tislelizumab (BGB-A317) Combined With or Without Anti-TIGIT Monoclonal Antibody Ociperlimab (BGB-A1217) in Participants With Recurrent or Metastatic Esophageal Squamous Cell Carcinoma
Status: COMPLETED
Conditions: Esophageal Squamous Cell Carcinoma
Interventions: DRUG: Tislelizumab|DRUG: Ociperlimab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Vitamin D Enriched Meat Project (Acute Study)
Status: COMPLETED
Conditions: Vitamin D Deficiency
Interventions: OTHER: Pork arm|OTHER: Chicken arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Ambu® Auragain™ as a Conduit for Intubation in Paediatrics
Status: COMPLETED
Conditions: Pediatric Endotracheal Intubation
Interventions: DEVICE: Intubation via AMBU® AURAGAIN™
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: rTMS for Motor and Mood Symptoms of Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson's Disease|Depression
Interventions: DEVICE: Repetitive transcranial magnetic stimulation (rTMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of Remote Evaluation and Treatment of Gestational Diabetes Mellitus
Status: COMPLETED
Conditions: Gestational Diabetes Mellitus|Pregnancy
Interventions: DEVICE: Blue tooth enabled glucose meter with smart phone application|BEHAVIORAL: Self home blood glucose monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Quantification of Myocardial Blood Flow Using Dynamic PET/CTA Fused Imagery
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: PROCEDURE: Invasive Cardiac Catheterization (ICA)|PROCEDURE: Coronary Computed Tomographic Angiogram (CCTA)|PROCEDURE: Dynamic Cardiac Positron Emission Tomography (dPET)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Intranasal Lidocaine for Prevention of Postoperative Nausea and Vomiting.
Status: WITHDRAWN
Conditions: Postoperative Nausea and Vomiting
Interventions: DRUG: 2% Lidocaine HCl topical solution|DRUG: 0.9% Sodium chloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Compare Two Different Sclerosing Agents in the Treatment of Venous Malformations
Status: ACTIVE_NOT_RECRUITING
Conditions: Venous Malformation
Interventions: DRUG: Bleomycin|DRUG: Fibrovein|DRUG: Bleomycin + Fibrovein
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Juvenile Primary Fibromyalgia Syndrome (JPFS) in an Adolescent Psychiatric Population
Status: COMPLETED
Conditions: Juvenile Primary Fibromyalgia Syndrome
Interventions: BEHAVIORAL: Psychoeducational Seminar and Relaxation Technique
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Linköping University Relational and Interpersonal Psychotherapy Project
Status: TERMINATED
Conditions: Major Depressive Disorder
Interventions: BEHAVIORAL: Brief Relational Therapy|BEHAVIORAL: Interpersonal Psychotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Remineralization of White Spot Lesions Using Self-Assembling Peptide P11-4 in Primary Anterior Teeth A Randomized Clinical Trial
Status: COMPLETED
Conditions: White Spot Lesions [Initial Caries] on Smooth Surface of Tooth
Interventions: OTHER: Self-Assembling Peptide P11-4
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: THeragnostic Utilities for Neoplastic DisEases of the Rectum by MRI Guided Radiotherapy
Status: UNKNOWN
Conditions: Neoadjuvant Chemoradiotherapy|Locally Advanced Rectal Cancer|Pathological Complete Response
Interventions: RADIATION: RT Dose escalation in LARC patients with an Early Regression Index > 13.1 at second week on nCRT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intraocular Cytokine in Recurrence of Polypoidal Choroidal Vasculopathy
Status: UNKNOWN
Conditions: Exudative Age-related Macular Degeneration|Polypoidal Choroidal Vasculopathy
Interventions: DRUG: ranibizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Trial of Anti-CD4 Antibody UB-421 in Combination With Optimized Background Antiretroviral Therapy in Patients With Multi-Drug Resistant HIV-1 Infection
Status: RECRUITING
Conditions: Multi-Drug Resistant Hiv-1 Infection|HIV-1 Infection
Interventions: BIOLOGICAL: UB-421
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy in Treating Patients With Advanced Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: carboplatin|DRUG: endocrine-modulating drug therapy|DRUG: estramustine phosphate sodium|DRUG: goserelin acetate|DRUG: leuprolide acetate|DRUG: paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Swedish Microinvasive Glaucoma Surgery Study (SMIGS)
Status: ACTIVE_NOT_RECRUITING
Conditions: Open Angle Glaucoma|Cataract|Kahook Dual Blade Glide|Istent Inject W|MIGS|Goniotomy
Interventions: PROCEDURE: Cataract surgery|PROCEDURE: KDB|PROCEDURE: Istent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Propofol on Postoperative Nausea and Vomiting.
Status: COMPLETED
Conditions: Postoperative Nausea and Vomiting
Interventions: DRUG: Propofol|DRUG: saline 0.9%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER