pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Increasing Uptake of EHR-enabled Population Health Outreach Strategies to Improve Diabetes Screening
Status: ENROLLING_BY_INVITATION
Conditions: Diabetes Mellitus, Type 2|Pre Diabetes
Interventions: BEHAVIORAL: Parkland Diabetes Detection Program (PDDP) Screening Invitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: EXercise Continuation Incorporating Technology Enhancements (EXCITE) Study
Status: COMPLETED
Conditions: Physical Inactivity
Interventions: BEHAVIORAL: ChiRunning training|BEHAVIORAL: unblinded accelerometer|BEHAVIORAL: participation in online social network|BEHAVIORAL: participation in study website|BEHAVIORAL: Technology support for behavior change
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of MYODM on Quality of Life, Fatigue and Hypersomnia in Patients With Myotonic Dystrophy Type 1
Status: COMPLETED
Conditions: Myotonic Dystrophy 1
Interventions: DIETARY_SUPPLEMENT: MYODM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ultrasonography Evaluation of Diaphragm Kinetics in Patients Undergoing Atrial Fibrillation Ablation With Cryoballoon
Status: RECRUITING
Conditions: Atrial Fibrillation|Phrenic Nerve Paralysis
Interventions: DIAGNOSTIC_TEST: Tissue Doppler Imaging|DIAGNOSTIC_TEST: M Mode Imaging
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effectiveness of an Online Exercise Program on Well-being of Postpartum Women
Status: COMPLETED
Conditions: Quality of Life|Physical Activity|Urinary Incontinence|Pelvic Organ Prolapse
Interventions: BEHAVIORAL: Rehabilitate your core
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparison Study of Sorafenib and 5-fluorouracil/Mitomycin for Metastatic Hepatocellular Carcinoma
Status: TERMINATED
Conditions: Carcinoma, Hepatocellular
Interventions: DRUG: 5-FU|DRUG: Mitomycin|DRUG: sorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Post-Market CorPath Registry on the CorPath 200 System in Percutaneous Coronary Interventions
Status: COMPLETED
Conditions: Coronary Artery Disease|Coronary Disease|Myocardial Ischemia|Heart Diseases|Cardiovascular Diseases|Arteriosclerosis|Arterial Occlusive Diseases|Vascular Diseases
Interventions: PROCEDURE: CorPath-assisted Percutaneous Coronary Intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Pilot Trial of Image-Guided Adaptive Radiotherapy for Head and Neck Cancer
Status: COMPLETED
Conditions: Head and Neck Cancer|Oropharyngeal Cancer
Interventions: RADIATION: Intensity Modulated Radiation Therapy|RADIATION: Adaptive Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: NIH Release/Relock Socket
Status: RECRUITING
Conditions: Lower Limb Amputation Below Knee (Injury)
Interventions: DEVICE: Release/Relock Socket - In Lab|DEVICE: Release/Relock Socket - Out of Lab|DEVICE: Release/Relock Socket & Control
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phase 2 a Study to Assess Safety and Pharmacokinetics of VAS203 in Patients With Traumatic Brain Injury
Status: COMPLETED
Conditions: Traumatic Brain Injury
Interventions: DRUG: VAS203|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Observational Study of MabThera/Rituxan (Rituximab) in Patients With Sero-Positive Rheumatoid Arthritis Who Are Non-Responders or Intolerant to a Single TNF-Inhibitor (PORTSMAB)
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Longitudinal TSPO PET Imaging With [18F]DPA-714 in PPMI (PPMI DPA-714 PET Imaging)
Status: NOT_YET_RECRUITING
Conditions: Parkinson Disease
Interventions: DRUG: [F-18]DPA714 administration IV
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: VAC077: Safety and Immunogenicity of the Pfs25-IMX313/Matrix-M Vaccine
Status: TERMINATED
Conditions: Malaria,Falciparum
Interventions: BIOLOGICAL: Pfs25-IMX313/Matrix-M1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study Of Safety And Tolerability Of GW786034 Given With Lapatinib In Cancer Patients
Status: COMPLETED
Conditions: Carcinoma, Renal Cell
Interventions: DRUG: GW786034|DRUG: lapatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PEGPH20 Plus Gemcitabine With Radiotherapy in Patients With Localized, Unresectable Pancreatic Cancer
Status: TERMINATED
Conditions: Pancreatic Adenocarcinoma Non-resectable
Interventions: DRUG: PEGylated Recombinant Human Hyaluronidase (PEGPH20)|DRUG: Gemcitabine|RADIATION: Radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial on a Strategy Combining Rapid Diagnostic Testing and Antimicrobial Stewardship to Improve Antibiotic Use in Patients With Hospital-acquired Pneumonia.
Status: RECRUITING
Conditions: Hospital-acquired Pneumonia
Interventions: DIAGNOSTIC_TEST: Rapid Diagnostic Testing|DIAGNOSTIC_TEST: Antimicrobial stewardship
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Phase 2 DoceRamPem for Patients With Metastatic or Recurrent NSCLC Who Progressed on Platinum-Doublet and PD-1/PD-L1 Blockade
Status: RECRUITING
Conditions: Metastatic Non-Small Lung Cell Cancer|Recurrent Non-Small Lung Cell Cancer|Stage IV Lung Cancer AJCC v8|Stage IVA Lung Cancer AJCC v8|Stage IVB Lung Cancer AJCC v8
Interventions: DRUG: Docetaxel|BIOLOGICAL: Pembrolizumab|BIOLOGICAL: Ramucirumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Umbilical Cord Blood Transplant With Added Sugar and Chemotherapy and Radiation Therapy in Treating Patients With Leukemia or Lymphoma
Status: COMPLETED
Conditions: Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive|Acute Biphenotypic Leukemia|Acute Leukemia|Acute Lymphoblastic Leukemia|Acute Lymphoblastic Leukemia in Remission|Acute Myeloid Leukemia|Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome|Chemotherapy-Related Leukemia|Chronic Lymphocytic Leukemia|Chronic Myelogenous Leukemia, BCR-ABL1 Positive|Chronic Myelomonocytic Leukemia|Hodgkin Lymphoma|Langerhans Cell Histiocytosis|Minimal Residual Disease|Myelodysplastic Syndrome|Myelodysplastic Syndrome With Excess Blasts|Non-Hodgkin Lymphoma|Recurrent Hodgkin Lymphoma|Refractory Acute Lymphoblastic Leukemia|Refractory Myelodysplastic Syndrome|Small Lymphocytic Lymphoma|Therapy-Related Myelodysplastic Syndrome
Interventions: BIOLOGICAL: Anti-Thymocyte Globulin|DRUG: Busulfan|DRUG: Clofarabine|DRUG: Cyclophosphamide|BIOLOGICAL: Filgrastim-sndz|DRUG: Fludarabine|DRUG: Melphalan|DRUG: Mycophenolate Mofetil|BIOLOGICAL: Rituximab|DRUG: Tacrolimus|RADIATION: Total-Body Irradiation|PROCEDURE: Umbilical Cord Blood Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The SOMNUS Study: Sedative Optimization Via Monitoring Neurological Status
Status: COMPLETED
Conditions: Delirium|Cognitive Impairment|Critically Ill
Interventions: OTHER: Sedation,RASS Targeted plus BIS Monitoring|OTHER: Sedation, RASS Targeted
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gastric Emptying During the Labour
Status: COMPLETED
Conditions: Pregnancy|Healthy Volunteers|Parturition
Interventions: OTHER: Ultrasound assessment of gastric emptying of a flavoured yoghourt.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Distalization by Miniscrew
Status: COMPLETED
Conditions: Distalization by Miniscrews
Interventions: DEVICE: miniscrew-supported Frog molar distalizing appliance|DEVICE: Standard Frog molar distalizing appliance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of Computer-based Cognitive Function Training on Cognitive Dysphagia After Stroke
Status: NOT_YET_RECRUITING
Conditions: Dysphagia
Interventions: BEHAVIORAL: routine rehabilitation treatment|BEHAVIORAL: Computer-assisted Cognitive Function Training|BEHAVIORAL: conventional cognitive training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Dapagliflozin in Early Diabetic Nephropathy in Type 1 Diabetes
Status: ACTIVE_NOT_RECRUITING
Conditions: Diabetic Kidney Disease|Type 1 Diabetes
Interventions: DRUG: dapagliflozin|DRUG: ACE inhibitor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stem Cell Study for Patients With Heart Disease
Status: TERMINATED
Conditions: Chest Pain|Chronic Myocardial Ischemia|Coronary Artery Disease|Angina|Myocardial Infarction
Interventions: GENETIC: Autologous peripheral blood CD34 positive cell therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Impact of Goode Health Beverage on Markers of Physiological and Neurocognitive Health
Status: RECRUITING
Conditions: Cardiovascular Diseases|Hypertension|Cognitive Decline|Diet, Healthy
Interventions: DIETARY_SUPPLEMENT: Goode Health Beverage|DIETARY_SUPPLEMENT: Vanilla Base Beverage Blend
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Effects of Soy Protein and Isoflavones on Glycemic Control, Insulin Sensitivity and Cardiovascular Risk Factors
Status: COMPLETED
Conditions: Diabetes|Cardiovascular Risk
Interventions: DIETARY_SUPPLEMENT: soy protein|DIETARY_SUPPLEMENT: isoflavones|DIETARY_SUPPLEMENT: milk protein
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose:
Clinical trial: Evaluate the Safety and Efficacy of AD-35 Tablet in Subjects With Mild to Moderate Alzheimer's Disease
Status: UNKNOWN
Conditions: Alzheimer's Disease
Interventions: DRUG: Placebo of AD-35 60mg /AD-35 30mg|DRUG: Placebo of AD-35 60mg /AD-35 60mg|DRUG: AD-35 30 mg + Placebo of AD-35 30 mg|DRUG: AD-35 60 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prophylactic Central Lymph Node Dissection in Papillary Thyroid Microcarcinoma
Status: COMPLETED
Conditions: Thyroid Cancer
Interventions: PROCEDURE: Prophylactic central lymph node dissection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Improving Patient Outcomes Through the Implementation of an IBD Biologic Care Pathway
Status: RECRUITING
Conditions: Inflammatory Bowel Diseases|Ulcerative Colitis|Crohn Disease
Interventions: OTHER: Biologic Care Pathway
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: BHV-7000 Acute Treatment of Bipolar Mania
Status: RECRUITING
Conditions: Bipolar Disorder
Interventions: DRUG: BHV-7000|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Anti-Inflammatory Treatment of Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Anti-inflammatory Combination Therapy|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: PTSD, AUD, and Interpersonal Conflict: Within-person Associations
Status: RECRUITING
Conditions: Stress Disorders, Post-Traumatic|Alcoholism
Interventions: BEHAVIORAL: Alcohol CBM|BEHAVIORAL: PTSD CBM|BEHAVIORAL: Alcohol Sham|BEHAVIORAL: PTSD Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Myofunctional Training for Obstructive Sleep Apnea Patients After Transoral Robotic Surgery
Status: UNKNOWN
Conditions: Sleep Apnea, Obstructive
Interventions: PROCEDURE: transoral robotic surgery|DEVICE: oral appliance|DEVICE: using continuous positive airway pressure|BEHAVIORAL: losing weights|COMBINATION_PRODUCT: oropharyngeal rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Decreased Dose Frequency in Participants With Systemic Juvenile Arthritis Who Experience Laboratory Abnormalities During Treatment With RoActemra/Actemra (Tocilizumab)
Status: COMPLETED
Conditions: Juvenile Idiopathic Arthritis
Interventions: DRUG: Tocilizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study of Hemin Therapy for Gastroparesis (Diabetes Mellitus)
Status: COMPLETED
Conditions: Gastroparesis|Diabetes Mellitus
Interventions: BIOLOGICAL: Hemin|BIOLOGICAL: Albumin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Work Physiological-Biomechanical Analysis of a Passive Exoskeleton to Support Occupational Lifting and Flexing Processes
Status: COMPLETED
Conditions: Passive Upper-limb Exoskeleton
Interventions: DEVICE: Laevo ®|DEVICE: No Laevo ®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Capecitabine, Temozolomide, and Bevacizumab for Metastatic or Unresectable Pancreatic Neuroendocrine Tumors
Status: COMPLETED
Conditions: Gastrinoma|Glucagonoma|Insulinoma|Pancreatic Polypeptide Tumor|Recurrent Islet Cell Carcinoma|Recurrent Pancreatic Cancer|Somatostatinoma|Stage III Pancreatic Cancer|Stage IV Pancreatic Cancer
Interventions: DRUG: Capecitabine|DRUG: Temozolomide|BIOLOGICAL: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Betamethasone (Betapred®) as Premedication for Reducing Postoperative Vomiting and Pain After Tonsillectomy
Status: RECRUITING
Conditions: Tonsillectomy|Pain|PONV|Bleeding
Interventions: DRUG: Betamethason Sodium Phosphate|DRUG: 10% glucose solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Casodex vs Placebo in Non-Metastatic Early Prostate Cancer
Status: COMPLETED
Conditions: Non-Metastatic Prostate Cancer
Interventions: DRUG: Bicalutamide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Yinxingmihuan Oral Solution in Treatment of Chest Pain After PCI
Status: COMPLETED
Conditions: Chronic Stable Angina
Interventions: DRUG: Yinxingmihuan oral solution|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: CArbohydrate Loading in Aortic Surgery
Status: NOT_YET_RECRUITING
Conditions: Abdominal Aortic Aneurysm|Leriche Syndrome
Interventions: DIETARY_SUPPLEMENT: carbohydrate-rich beverage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Tolerability and Immunogenicity Study of Fluval AB Influenza Vaccine in Adults and Elderly Persons
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Vaccination with Fluval AB influenza vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Time-Restricted Feeding(TRF) on Overweight/Obese Women With Polycystic Ovarian Syndrome (PCOS)
Status: COMPLETED
Conditions: Polycystic Ovary Syndrome (PCOS)|Overweight and Obesity
Interventions: BEHAVIORAL: Time Restricted Feeding|BEHAVIORAL: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study of ET140203 T Cells in Adults With Advanced Hepatocellular Carcinoma (ARYA-1)
Status: TERMINATED
Conditions: Hepatocellular Carcinoma|Liver Cancer|Liver Neoplasm|Metastatic Liver Cancer
Interventions: BIOLOGICAL: ET140203 autologous T cell product
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: FIT Study (Functional Outcomes In Trauma Study)
Status: ACTIVE_NOT_RECRUITING
Conditions: Patient Reported Outcome Measures|Recovery of Function|Rehabilitation|Disability Evaluation|Trauma Centers|Trauma Severity Indices|Advanced Trauma Life Support Care|Multiple Trauma/Injuries|Wounds and Injuries|Orthopedic Disorder|Surgery
Interventions: OTHER: Online Questionnaires|OTHER: Qualitative Interviews
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Dalantercept in Treating Patients With Recurrent or Persistent Endometrial Cancer
Status: COMPLETED
Conditions: Endometrial Adenocarcinoma|Endometrial Clear Cell Adenocarcinoma|Endometrial Mixed Adenocarcinoma|Endometrial Mucinous Adenocarcinoma|Endometrial Serous Adenocarcinoma|Endometrial Squamous Cell Carcinoma|Endometrial Transitional Cell Carcinoma|Endometrial Undifferentiated Carcinoma|Recurrent Uterine Corpus Carcinoma
Interventions: BIOLOGICAL: Dalantercept|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Safety of Liraglutide Compared to Sitagliptin, Both in Combination With Metformin in Chinese Subjects With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: liraglutide|DRUG: sitagliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fascial Versus Standard Neck Dissection in Patients With N1b Papillary Thyroid Carcinoma
Status: COMPLETED
Conditions: Patients With Papillary Thyroid Cancer and N1b Status
Interventions: PROCEDURE: Fascial Neck Dissection|PROCEDURE: Standard Neck Dissection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Bear Bile Pill as add-on the Treatment of MDD
Status: UNKNOWN
Conditions: Major Depressive Disorder
Interventions: DRUG: bear bile pill|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Rosuvastatin at Preventing the Progression of Atherosclerosis in HIV Positive Patients
Status: TERMINATED
Conditions: Atherosclerosis|HIV Infections
Interventions: DRUG: Rosuvastatin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Enhance Physical Activity and Intergenerational Relationship Via Connect Active Program (CAP): A Pilot Randomized Controlled Trial
Status: NOT_YET_RECRUITING
Conditions: Elderly|Physical Inactivity
Interventions: OTHER: Connect Active Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Mobile Internet-based Remote Home Rehabilitation Improves Prognostic Function and Life Quality in Pulmonary Hypertension
Status: NOT_YET_RECRUITING
Conditions: Pulmonary Hypertension
Interventions: BEHAVIORAL: tele-rehabilitation training|BEHAVIORAL: health propaganda and education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Traumatic Memory Modification Using Memory Reconsolidation and Propranolol Among Adolescents With PTSD
Status: NOT_YET_RECRUITING
Conditions: Post Traumatic Stress Disorder
Interventions: DRUG: Propranolol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tumor-Treating Fields Therapy in Preventing Brain Tumors in Participants With Extensive-Stage Small Cell Lung Cancer
Status: TERMINATED
Conditions: Extensive Stage Small Cell Lung Carcinoma
Interventions: PROCEDURE: Tumor Treating Fields (TTF) Therapy|DEVICE: NovoTTF-200A Device|OTHER: Quality-of-Life Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Temsirolimus and Bevacizumab in Treating Patients With Stage III or Stage IV Malignant Melanoma
Status: COMPLETED
Conditions: Recurrent Melanoma|Stage IIIB Skin Melanoma|Stage IIIC Skin Melanoma|Stage IV Skin Melanoma
Interventions: BIOLOGICAL: Bevacizumab|OTHER: Laboratory Biomarker Analysis|DRUG: Temsirolimus|PROCEDURE: Therapeutic Conventional Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non-invasive Assessment of the Current State of Hydration in Children by Ultrasound
Status: COMPLETED
Conditions: Gastroenteritis|Diabetes Mellitus (Ketoacidosis)
Interventions: PROCEDURE: Intravenous administration of fluids
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Perineal Flap Reconstruction Following Surgery for Advanced Pelvic Malignancy
Status: COMPLETED
Conditions: Pelvic Cancer|Rectal Cancer|Flap Disorder|Flap Ischemia|Flap Necrosis|Perioperative Complication
Interventions: PROCEDURE: Flap reconstruction
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pharmacokinetic, Safety and Immunogenicity Study of CMAB015 and Cosentyx in Healthy Volunteers
Status: COMPLETED
Conditions: Psoriasis
Interventions: BIOLOGICAL: Secukinumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Docetaxel and Flavopiridol in Treating Patients With Refractory Metastatic Pancreatic Cancer
Status: COMPLETED
Conditions: Adenocarcinoma of the Pancreas|Recurrent Pancreatic Cancer|Stage IV Pancreatic Cancer
Interventions: DRUG: alvocidib|DRUG: docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Effectiveness of Autologous Bone Marrow-Derived Mesenchymal Stem Cells in Fibrin to Treat Chronic Wounds
Status: TERMINATED
Conditions: Non Healing Wounds
Interventions: GENETIC: Stem Cell
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intrathecal Hydromorphone for Labor Analgesia
Status: TERMINATED
Conditions: Pregnancy
Interventions: DRUG: Hydromorphone|DRUG: Hyperbaric bupivacaine|DRUG: Fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Influence of Oxytocin on Intrapartum Fetal Well-being and Delivery Outcomes in Patients Receiving Epidural Analgesia
Status: ENROLLING_BY_INVITATION
Conditions: Uterine Contraction|Oxytocin|Labor Progress|Fetal Doppler|Labor Epidural Analgesia|Labor Pain
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Efficacy of Additional Osteotomies to Correct Hallux Valgus
Status: ACTIVE_NOT_RECRUITING
Conditions: Hallux Valgus
Interventions: PROCEDURE: additional osteotomies
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of CDK4/6 Inhibitor Combined With PD-L1 Monoclonal Antibody in the Treatment of PD-1/PD-L1 Resistance and Abnormal Cell Cycle Digestive System Tumors
Status: UNKNOWN
Conditions: Digestive System Tumors
Interventions: DRUG: TQB3616 capsules＋ TQB2450 injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Utilization of Educational Interventions in Completion of Genetic Testing in Black Patients With High-Risk Prostate Cancer
Status: NOT_YET_RECRUITING
Conditions: Prostate Cancer
Interventions: BEHAVIORAL: Educational video
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Comparison of the Long Term Effects of the Traditional and Modified Posterior Shoulder Stretching Exercise in Subacromial Impingement Syndrome
Status: RECRUITING
Conditions: Subacromial Impingement Syndrome
Interventions: OTHER: Modified static cross-body posterior shoulder stretching|OTHER: Traditional static cross-body posterior shoulder stretching|OTHER: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Weightlessness Associated Cephalad Fluid Shifts; The Potential to Evaluate Venous and Lymphatic Dysfunction
Status: COMPLETED
Conditions: Fluid Retention Tissue|Perfusion; Complications
Interventions: OTHER: Manual Lymphatic Drainage|DEVICE: Near infrared spectroscopy|DEVICE: Temperature|DEVICE: Tissue Dialectic Constant
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Assess the Effects of PT003 and Placebo MDI on Specific Image Based Airway Volumes and Resistance in Subjects With Moderate to Severe COPD
Status: COMPLETED
Conditions: COPD
Interventions: DRUG: GFF MDI (PT003) 14.4/9.6μg|DRUG: Placebo MDI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Testing an App-Based Approach to Reading and Screen Time Guidance for Parents of Infants
Status: COMPLETED
Conditions: Literacy|Parent-Child Relations|Language Development
Interventions: BEHAVIORAL: Reading Bees app and children's book to enhance parent-infant reading quality (0-2 month visit)|BEHAVIORAL: Reading Bees app and children's book to encourage alternatives to digital media (6-month visit)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Anti-anxiety Biotics for Breast Cancer Survivors
Status: TERMINATED
Conditions: Anxiety Generalized|Breast Cancer Female
Interventions: DIETARY_SUPPLEMENT: probiotic plus prebiotic supplement|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Quantitation of Left Ventricular Ejection Fraction as Part of F-18 FDG Whole Body PET/CT Scans For Tumor Staging
Status: TERMINATED
Conditions: Advanced Cancers
Interventions: PROCEDURE: Nuclear Medicine Cardiac Scan|PROCEDURE: PET/CT Cardiac Scan
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase 2b Study Evaluating the Safety and Efficacy of AR-15512 Ophthalmic Solution for the Treatment of Dry Eye Disease
Status: COMPLETED
Conditions: Dry Eye Disease
Interventions: DRUG: AR-15512 Ophthalmic Solution|DRUG: AR-15512 Ophthalmic Solution Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Interchangeable Guide in Ridge Splitting Flapless Technique for Implant Placement
Status: COMPLETED
Conditions: Anterior Maxillary Narrow Ridge
Interventions: PROCEDURE: ridge splitting flapless technique using interchangeable guide followed by implant placement
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adverse Cardiovascular Events During Painless Gastroscopy Diagnosis and Treatment in Elderly Frail Patients
Status: COMPLETED
Conditions: Anesthesia
Interventions: PROCEDURE: The conscious sedation group|PROCEDURE: Intravenous general anesthesia group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Demonstrate Equivalence of Formoterol 12 and 24 µg Delivered Via Two Types of Single Dose Dry Powder Inhalers (Concept1 and Aerolizer)
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: formoterol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Intramuscular Ketorolac Versus Oral Ibuprofen for Pain Relief in First Trimester Suction Curettage
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Ketorolac|DRUG: Ibuprofen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Trial of Interleukin 12 Gene Therapy for Metastatic Pancreatic Cancer
Status: COMPLETED
Conditions: Metastatic Pancreatic Cancer
Interventions: BIOLOGICAL: Ad5-yCD/mutTKSR39rep-hIL12
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intestinal Ultrasound Versus Double Balloon Enteroscopy (DBE) in Diagnosis of Malabsorption Syndrome
Status: UNKNOWN
Conditions: Malabsorption Syndrome
Interventions: PROCEDURE: ultrasound, double balloon enteroscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effects of MK7418 on Diuresis and Renal Function in Congestive Heart Failure Patients
Status: COMPLETED
Conditions: Congestive Heart Failure|Renal Impairment
Interventions: DRUG: rolofyline|DRUG: Comparator Placebo (unspecified)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An Intervention to Increase Engagement With Hypertension Care for American Indian Patients
Status: COMPLETED
Conditions: Hypertension
Interventions: BEHAVIORAL: Intervention Values Affirmation|BEHAVIORAL: Control Values Affirmation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Effect of Eyemasks on Neonatal Stress Following Dilated Retinal Examination
Status: COMPLETED
Conditions: Retinopathy of Prematurity|Pain|Premature Infant|Retinal Disease
Interventions: DEVICE: Phototherapy Mask
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Duration of Therapy for Thrombosis in Children
Status: COMPLETED
Conditions: Venous Thrombosis
Interventions: OTHER: Shortened duration (6 weeks) of anticoagulant therapy|OTHER: Conventional duration (3 months) of anticoagulant therapy|OTHER: No Intervention|OTHER: No Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cardiometabolic Consequences of the Loss of Ovarian Function
Status: RECRUITING
Conditions: Menopause|Estrogen Deficiency|Aging|Adiposity
Interventions: DRUG: Degarelix|DRUG: Transdermal Estradiol Patch|DRUG: Transdermal Placebo Patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Beyond Ageing Project: A Study for the Prevention of Depression
Status: COMPLETED
Conditions: Depression|Depressive Disorder
Interventions: DRUG: Folate (400mcg) and Vitamin B12 (100 mcg)|BEHAVIORAL: mediated physical activity promotion|BEHAVIORAL: Mental health literacy|DRUG: placebo|BEHAVIORAL: Nutrition information|BEHAVIORAL: pain and arthritis management information
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Comparison of the Safety and Effectiveness of Fluconazole or Clotrimazole in the Treatment of Fungal Infections of the Mouth and Throat in Patients With AIDS
Status: COMPLETED
Conditions: Candidiasis, Oral|HIV Infections
Interventions: DRUG: Clotrimazole|DRUG: Fluconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Early Mobilization After Total Knee Arthroplasty
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DRUG: General Anesthesia|DRUG: Neuraxial anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Timing to Minimally Invasive Surgery After Neoadjuvant Chemoradiotherapy for Rectal Cancer
Status: RECRUITING
Conditions: Rectal Cancer
Interventions: PROCEDURE: Surgery after 8 weeks from chemoradiation treatment|PROCEDURE: Surgery after 12 weeks from chemoradiation treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anemia in Heart Failure With a Preserved Ejection Fraction (HFPEF)
Status: COMPLETED
Conditions: Anemia
Interventions: DRUG: Erythropoietin alpha|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Chlorhexidine Bathing Effect on Clostridium Difficile Rates
Status: COMPLETED
Conditions: Clostridium Difficile
Interventions: DRUG: Sage 2% Chlorhexidine Gluconate Cloth Patient Preoperative Skin Preparation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Research Study to Look at How Well Semaglutide is at Lowering Weight When Taken Together With an Intensive Lifestyle Program
Status: COMPLETED
Conditions: Overweight|Obesity
Interventions: DRUG: Semaglutide|DRUG: Placebo (semaglutide)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pulse Ultrasound and Kneading Massage in Non- Specific Chronic Low Back Pain
Status: COMPLETED
Conditions: Non Specific Low Back Pain
Interventions: OTHER: PULSE ULTRASOUND|OTHER: KNEADING MASSAGE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility Trial of a Tailored Smoking Cessation App for People With Serious Mental Illness
Status: COMPLETED
Conditions: Nicotine Addiction|Serious Mental Illness
Interventions: DEVICE: Learn to Quit App|DRUG: Nicotine patch|DRUG: Nicotine lozenge|BEHAVIORAL: Technical Coaching|DEVICE: NCI QuitGuide App
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Midodrine vs Abdominal Compression on Cardiovascular Risk Markers in Autonomic Failure Patients
Status: RECRUITING
Conditions: Neurogenic Orthostatic Hypotension|Autonomic Failure|Pure Autonomic Failure|Multiple System Atrophy|Parkinson Disease
Interventions: DRUG: Midodrine|DRUG: Placebo pill|DEVICE: Abdominal compression|DEVICE: sham compression
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Home Based Computer Gaming Hand Exercise Regimen for People With Arthritis Affecting the Hands
Status: COMPLETED
Conditions: Rheumatoid Arthritis|Osteoarthritis of Hands
Interventions: OTHER: Conventional hand exercise program|OTHER: Computer gaming hand exercise regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: tDCS and Motor Training and Motor Deficit After Stroke
Status: COMPLETED
Conditions: Stroke
Interventions: DEVICE: tDCS (Endomed 482; Enraf-Nonius B.V.)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Development and Evaluation of an HIV, STD, and Pregnancy Prevention Program for Middle School Students
Status: COMPLETED
Conditions: HIV Infections|Sexually Transmitted Diseases|Pregnancy
Interventions: BEHAVIORAL: HIV, STD, and pregnancy prevention curriculum|BEHAVIORAL: Standard sexual education curriculum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Safety and Effectiveness of the Essure (Model ESS505) Device to Prevent Pregnancy in Women
Status: ACTIVE_NOT_RECRUITING
Conditions: Contraception
Interventions: DEVICE: ESS505 (BAY1454033)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of BMS-863233 in Patients With Advanced and/or Metastatic Solid Tumors
Status: TERMINATED
Conditions: Advanced Solid Cancers|Metastatic Cancer
Interventions: DRUG: Cdc7-inhibitor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Everolimus Stent in Myocardial Infarction
Status: COMPLETED
Conditions: Acute Myocardial Infarction
Interventions: DEVICE: everolimus eluting stent|DEVICE: sirolimus eluting stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anticoagulant/Antiaggregant Use and Postoperative Bleeding Risk in Patients With Bladder Tumor and Benign Prostatic Hyperplasia
Status: COMPLETED
Conditions: Hematuria|Retention, Urinary|Operative Bleeding|Blood Transfusion Complication
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Coronary and Structural Interventions Ulm - Coronary Chronic Total Occlusions
Status: COMPLETED
Conditions: Coronary Artery Disease|Ischemic Heart Disease|Stable Angina
Interventions: DEVICE: stent or scaffold
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gemcitabine Plus Busulfan, Melphalan and Hematopoietic Cell Transplant for Advanced Lymphoid Malignancies
Status: COMPLETED
Conditions: Leukemia|Lymphoma|Myeloma
Interventions: DRUG: Busulfan|DRUG: Gemcitabine|DRUG: Melphalan|OTHER: Hematopoietic Cell Transplantation|DRUG: Rituximab for Patients with B-Cell Malignancies|DRUG: Palifermin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Comparing On-Demand Treatment With Two Prophylaxis Regimens Of BeneFIX In Patients With Severe Hemophilia B
Status: COMPLETED
Conditions: Hemophilia B
Interventions: DRUG: Recombinant Coagulation Factor IX (BeneFIX)|DRUG: Recombinant Coagulation Factor IX (BeneFIX)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: EUS Guided Neurolysis Celiac Block w/wo Bupivacaine in Patient Being Treated Palliatively for Pancreatic Cancer
Status: TERMINATED
Conditions: Pancreatic Cancer
Interventions: PROCEDURE: Endoscopic ultrasound-guided celiax plexus neurolysis|DRUG: Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy and Safety of HS-25 or in Combination With Atorvastatin in Chinese Adults With Primary Hypercholesterolemia
Status: UNKNOWN
Conditions: Primary Hypercholesterolemia
Interventions: DRUG: HS-25 10mg|DRUG: HS-25 10mg combination with Atorvastatin|DRUG: HS-25 20mg combination with Atorvastatin|DRUG: Atorvastatin 10mg|DRUG: HS-25 20mg|DRUG: Placebe of HS-25 and Atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Oral VT-1161 in the Treatment of Patients With Recurrent Vaginal Candidiasis (Yeast Infection)
Status: COMPLETED
Conditions: Recurrent Vulvovaginal Candidiasis
Interventions: DRUG: VT-1161|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The "Metabolically-obese Normal-weight" Phenotype and Its Reversal by Calorie Restriction
Status: COMPLETED
Conditions: Glucose Metabolism Disorders|Obesity, Visceral|Obesity; Endocrine|Insulin Sensitivity/Resistance
Interventions: BEHAVIORAL: Calorie restriction
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Oxytocin for Weight Loss in Adolescents
Status: RECRUITING
Conditions: Obesity, Adolescent|Oxytocin
Interventions: DRUG: Oxytocin nasal spray|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Impact of the Repositioning Schedule Adapted to the Risk of Pressure Ulcer of Patients in Intensive Care Unit
Status: RECRUITING
Conditions: Pressure Ulcer|Ischemic|Ischemic Ulcer
Interventions: PROCEDURE: Positioning schedule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Hyaluronic Acid Delivery: CO2 Laser Versus Thulium Laser Treatment
Status: RECRUITING
Conditions: Aging Skin
Interventions: OTHER: CO2 laser + HA|OTHER: Thulium laser + HA
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Motivational Program on Physical Activity in Cardio-respiratory Patients: an RCT Study
Status: RECRUITING
Conditions: Cardiorespiratory Failure
Interventions: BEHAVIORAL: Motivational group|OTHER: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Effects of Probiotics Combined With Glutamine in the Prevention and Treatment of Radiation Proctitis
Status: RECRUITING
Conditions: Radiation Proctitis|Probiotics|Glutamine|Gut Microbiota|Bifidobacterium
Interventions: DRUG: Live Combined Bifidobacterium and Lactobacillus Tablets、Compound Glutamine Entersoluble capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effects of Manual IC With and Without SCS on SCM Tightness With FHP
Status: RECRUITING
Conditions: Neck Pain
Interventions: OTHER: Experimental: Manual Ischemic Compression with Strain Counter Strain technique|OTHER: Active Comparator: Manual Ischemic Compression
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Cabozantinib in Combination With Cetuximab in Patients With Recurrent or Metastatic Head and Neck Squamous Cell Cancer
Status: COMPLETED
Conditions: Head and Neck Squamous Cell Cancer|Recurrent Head and Neck Squamous Cell Cancer|Metastatic Head and Neck Squamous Cell Cancer
Interventions: DRUG: Cabozantinib|DRUG: Cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Narrative E-Writing Intervention (NeW-I) for Parents of Children With Chronic Life-Threatening Illness
Status: UNKNOWN
Conditions: Parent of Child With Chronic Life-threatening Illness
Interventions: OTHER: NeW-I group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Residual Curarization and Its Incidence at Tracheal Extubation (P08194)
Status: COMPLETED
Conditions: Observation of Neuromuscular Block
Interventions: DEVICE: TOF-Watch SX® Monitoring of NMB
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER