pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Study of SOR007 Ointment for Actinic Keratosis
Status: COMPLETED
Conditions: Actinic Keratosis
Interventions: DRUG: SOR007 (Uncoated Nanoparticulate Paclitaxel) Ointment|OTHER: SOR007 Ointment Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Platelet-Rich Plasma Intra-Articular Injection in Treating Hemophilic Arthropathy
Status: COMPLETED
Conditions: Hemophilia|Hemophilic Arthropathy
Interventions: BIOLOGICAL: Platelet-Rich Plasma Intra-Articular Injection|DRUG: Hyaluronic Acid Viscosupplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Saphenous Nerve Block After Tibial Plateau ORIF
Status: NOT_YET_RECRUITING
Conditions: Tibial Plateau Fracture|Pain, Postoperative
Interventions: PROCEDURE: Saphenous Nerve Block with Ropivacaine Treatment|PROCEDURE: Saphenous Nerve Block with Saline Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acupuncture for Patients With Diarrhea-predominant IBS or Functional Diarrhea: a Randomized Controlled Trial
Status: COMPLETED
Conditions: Diarrhea-predominant Irritable Bowel Syndrome|Functional Diarrhea
Interventions: OTHER: acupuncture|OTHER: acupuncture group2|OTHER: acupuncture group3|DRUG: Loperamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating the State of Microvessels by Minimum Rise Time (MRT01)
Status: COMPLETED
Conditions: Healthy
Interventions: DEVICE: RESPeRATE (Paced Breathing)|DEVICE: Quantum Warp10 (Red LED)|DEVICE: Omnilux new-U (Near Infrared LED)|OTHER: Heat/cold provocation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy Combined Fecal Immunochemical Test-Sigmoidoscopy for the Detection of Advanced Colorectal Neoplasia
Status: UNKNOWN
Conditions: Colorectal Adenoma
Interventions: PROCEDURE: FIT-sigmoidoscopy|PROCEDURE: Colonoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Validation/Evaluation of Multimodal Imaging Combining 3D Ultrasound and Stress Myocardial Scintigraphy in the Diagnosis of Coronary Artery Disease
Status: WITHDRAWN
Conditions: Coronary Artery Disease|Coronary Disease
Interventions: PROCEDURE: Stress ultrasound|PROCEDURE: Scintigraphy|PROCEDURE: Coronary angiography
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Pilot Study of the Efficacy of Recombinant Alpha Interferon (IFN-A2b) and Zidovudine (AZT) in the Treatment of Progressive Multifocal Leukoencephalopathy (PML) Complicating HIV-1 Infection
Status: COMPLETED
Conditions: HIV Infections|Leukoencephalopathy, Progressive Multifocal
Interventions: DRUG: Interferon alfa-2b|DRUG: Zidovudine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Project FIRST - Financial Incentives to Reduce Substance Use and Improve Treatment
Status: COMPLETED
Conditions: HIV|Opiate Dependence
Interventions: BEHAVIORAL: Abstinence-reinforcing contingency management intervention|BEHAVIORAL: Performance Feedback intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness and Suitability of the Online Mobile Application for the Mental and Physical Health of Cancer Patients
Status: RECRUITING
Conditions: Cancer
Interventions: BEHAVIORAL: Mindfulness-Based Cognitive Therapy (MBCT-Ca) - online|BEHAVIORAL: Positive Psychology - online|BEHAVIORAL: Autogenic Training - online
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: This is a Study to Evaluate if Music Therapy Can Reduce Stress and Increase Satisfaction of Patients Undergoing Ambulatory Surgery
Status: COMPLETED
Conditions: Stress|Personal Satisfaction
Interventions: OTHER: Music Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Pharmacokinetics, Pharmacodynamics and Anti-tumor Activity of Sorafenib and Eribulin in Combination
Status: COMPLETED
Conditions: Neoplasms
Interventions: DRUG: Sorafenib (Nexavar, BAY43-9006)|DRUG: Eribulin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of REACT in Subjects With Type 2 Diabetes Mellitus and Chronic Kidney Disease
Status: RECRUITING
Conditions: Type 2 Diabetes Mellitus|Chronic Kidney Diseases
Interventions: BIOLOGICAL: Renal Autologous Cell Therapy (REACT)|PROCEDURE: Sham Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Effect of Ursodeoxycholic Acid in Patients With Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Placebo|DRUG: Ursodeoxycholic acid (UDCA) 500 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety and Efficacy of Selgantolimod (SLGN)-Containing Combination Therapies for the Treatment of Chronic Hepatitis B (CHB)
Status: COMPLETED
Conditions: Chronic Hepatitis B
Interventions: DRUG: Tenofovir Alafenamide|DRUG: VIR-2218|DRUG: Nivolumab|DRUG: Selgantolimod
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Incidence of the Intravascular Injection During S1 Transforaminal Epidural Steroid Injection in Two Approaches: Anteroposterior Versus Oblique
Status: COMPLETED
Conditions: Lumbosacral Radicular Pain
Interventions: PROCEDURE: anteroposterior approach group|PROCEDURE: oblique approach group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose:
Clinical trial: Alcoholic Liver Disease and the Gut Microbiome
Status: RECRUITING
Conditions: Alcohol Use Disorder|Alcoholic Liver Disease|Microbiome
Interventions: DRUG: VSL #3 112.5 Capsule|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Investigation Into the Efficacy of a Botanical Supplement to Provide Period Relief
Status: COMPLETED
Conditions: Menstrual Pain|Premenstrual Syndrome
Interventions: OTHER: Pamprin Botanicals|COMBINATION_PRODUCT: Pamprin Botanicals + Pamprin Menstrual Pain Relief
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Interpectoral-pectoserratus Plane Block for Minimally Invasive Aortic Valve Replacement Via Right Anterior Minithoracotomy
Status: NOT_YET_RECRUITING
Conditions: Analgesic Effect
Interventions: DRUG: Levobupivacaine Hydrochloride 0.25 % Injectable Solution|DRUG: Sodium chloride 0.9%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Analgesic Efficacy and Management of Opioid-induced Constipation (OIC) for Uncontrolled Moderate - Severe Low Back Pain
Status: COMPLETED
Conditions: Low Back Pain
Interventions: DRUG: Oxycodone/Naloxone controlled-release|DRUG: Oxycodone HCl controlled-release|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Raw Versus Roasted Fenugreek Seed Powder in Reducing Blood Glucose Levels in Type 2 Diabetic Patients
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DIETARY_SUPPLEMENT: Raw fenugreek seed powder|DIETARY_SUPPLEMENT: Roasted fenugreek seed powder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess S-309309 in Healthy and Obese Participants
Status: COMPLETED
Conditions: Obesity
Interventions: DRUG: S-309309|DRUG: Midazolam|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: CO2 Laser Therapy for the Treatment of GSM in Patients With Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer|Genitourinary Syndrome of Menopause
Interventions: DEVICE: Fractional/Pixel CO2 laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Drug-drug Interaction Study of Eltrombopag and Cyclosporine in Healthy Subjects
Status: COMPLETED
Conditions: Purpura, Thrombocytopenic, Idiopathic
Interventions: DRUG: Eltrombopag|DRUG: Cyclosporine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study of Foscarnet Plus Ganciclovir in the Treatment of Cytomegalovirus of the Eye in Patients With AIDS Who Have Already Been Treated With Ganciclovir
Status: COMPLETED
Conditions: Cytomegalovirus Retinitis|HIV Infections
Interventions: DRUG: Foscarnet sodium|DRUG: Ganciclovir
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Reactogenicity, Safety, and Immunogenicity of the Third Generation Hepatitis B Vaccine
Status: COMPLETED
Conditions: Healthy
Interventions: BIOLOGICAL: CVI-HBV-001|BIOLOGICAL: Conventional Hepatitis B vaccine (20 μg)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Study Of Nintedanib Compared To Chemotherapy in Patients With Recurrent Clear Cell Carcinoma Of The Ovary Or Endometrium
Status: UNKNOWN
Conditions: Ovarian Clear Cell Carcinoma|Endometrial Clear Cell Carcinoma
Interventions: DRUG: Nintedanib|DRUG: Paclitaxel|DRUG: Pegylated Liposomal Doxorubicin (PLD)|DRUG: Topotecan|DRUG: Carboplatin|DRUG: Doxorubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study to Evaluate the Effect of New Antiviral Drugs on HCV Infection.
Status: UNKNOWN
Conditions: Chronic Hepatitis, C Virus
Interventions: DRUG: Ombitasvir-Paritaprevir-Ritonavir|DRUG: Dasabuvir|DRUG: Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Variation in Natremia Using Two Different Maintenance Intravenous Fluids in Postsurgical Hospitalized Children
Status: COMPLETED
Conditions: Hyponatremia
Interventions: DRUG: 0.45% NaCl/dextrose 5%|DRUG: 0.3% NaCl/dextrose 5%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Determine the Safety and Tolerability of TG-C in Subjects With Back Pain Due to Degenerative Disc Disease
Status: NOT_YET_RECRUITING
Conditions: Degenerative Disc Disease
Interventions: BIOLOGICAL: TG-C High Dose|BIOLOGICAL: TG-C Mid Dose|BIOLOGICAL: TG-C Low Dose|BIOLOGICAL: Sham Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Belimumab Treatment in a Subpopulation of Systemic Lupus Erythematosus (SLE) Patients: a Pooled Analysis of BLISS-52 and BLISS-76
Status: COMPLETED
Conditions: Systemic Lupus Erythematosus
Interventions: DRUG: Belimumab 1 mg/kg|DRUG: Belimumab 10 mg/kg|DRUG: Placebo
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of Effectiveness of Cell Phone Technology as Community Based Intervention to Improve Exclusive Breast Feeding
Status: UNKNOWN
Conditions: Malnutrition in Pregnancy|Other Disorders of Breast and Lactation Associated With Childbirth
Interventions: BEHAVIORAL: Lactational Counseling by Cell phone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Shiatsu Adjuvant Therapy And Placebo For Schizophrenia
Status: UNKNOWN
Conditions: Schizophrenia
Interventions: BEHAVIORAL: Acupressure adjuvant therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Inotuzumab Ozogamicin Combined to Chemotherapy in Older Patients With Philadelphia Chromosome-negative CD22+ B-cell Precursor ALL
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Lymphoblastic Leukemia (ALL) - Philadelphia Chromosome (Ph)-Negative CD22+ B-cell Precursor (BCP)
Interventions: DRUG: Inotuzumab ozogamicin (INO)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cycle-ergometer in the Postoperative of Thoracic Surgery
Status: UNKNOWN
Conditions: Functional Capacity|Fatigue|Dyspnea|Muscle Strength
Interventions: OTHER: Interval effort group|OTHER: Continuous effort group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PARP Inhibition for Triple Negative Breast Cancer (ER-/PR-/HER2-)With BRCA1/2 Mutations
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Cisplatin|DRUG: Rucaparib|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adaptation and Feasibility of the Community-Based Anxiety Program Tailored for Autism (CAPTA)
Status: RECRUITING
Conditions: Anxiety|Autism Spectrum Disorder|Separation Anxiety|Generalized Anxiety Disorder|Social Anxiety Disorder of Childhood
Interventions: BEHAVIORAL: Cognitive Behavioral Therapy|OTHER: Treatment as Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Scaling Up an Integrated Approach to Improve Delivery Care in North Guatemala With Stepped Wedge Design
Status: COMPLETED
Conditions: Maternal Sepsis During Labor|Hemorrhage, Postpartum|Eclampsia; Complicating Pregnancy|Pre-Eclampsia|Perinatal Morbidity
Interventions: OTHER: QVLM Intervention package
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Traumastem® Versus Surgicel® for the Secondary Treatment of Local Bleeding in Patients Undergoing Hepatic Resection
Status: COMPLETED
Conditions: Liver Hemorrhage
Interventions: COMBINATION_PRODUCT: Traumastem®|COMBINATION_PRODUCT: Surgicel®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Comparison of ATI-5923, a Novel Vitamin K Antagonist, With Warfarin in Patients Requiring Chronic Anticoagulation
Status: UNKNOWN
Conditions: Atrial Fibrillation|Atrial Flutter|Venous Thromboembolic Disease|Myocardial Infarction|Cardiomyopathy
Interventions: DRUG: ATI-5923|DRUG: Coumadin (warfarin)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Iron Deficiency as an Ignored Cause of Infertility
Status: UNKNOWN
Conditions: Iron Deficiency|Infertility
Interventions: DRUG: Ferric Carboxymaltose Injection|DRUG: NaCl infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study in Healthy Men to Find Out How BI 425809 is Taken up and Handled by the Body
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BI 425809 mixed with [C-14] BI425809
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Technical Development of Cardiovascular Magnetic Resonance Imaging
Status: COMPLETED
Conditions: Cardiomyopathy|Congenital Heart Disease|Cardiovascular Disease|Cardiac Magnetic Resonance Imaging|Acute Myocardial Infarction
Interventions: DEVICE: Siemens MRI scanner
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Multidisciplinary Approach to Improve Adherence to Medical Recommendations in Older Adults
Status: UNKNOWN
Conditions: Medication Adherence|Aging|Multidisciplinary Communication|Fall|Hospital Discharge
Interventions: BEHAVIORAL: Educational training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Cadonilimab as Neoadjuvant Therapy in Resectable Stage II-III MSI-H/dMMR Colorectal Cancer
Status: NOT_YET_RECRUITING
Conditions: Colorectal Cancer|Mismatch Repair-deficient (dMMR)|Microsatellite Instability-high (MSI-H)|Neoadjuvant Therapy
Interventions: DRUG: Cadonilimab (®), a PD-1/CTLA-4 bi-specific antibody
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Evaluating the Safety and Efficacy of ATG-010 Combined With Chemotherapy Sequential With ATG-010 Monotherapy Maintenance in Peripheral T- and NK/T-cell Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Peripheral T-cell Lymphoma|NK/T-cell Lymphoma
Interventions: COMBINATION_PRODUCT: ICE [ifosfamide+carboplatin+etoposide]|COMBINATION_PRODUCT: GEMOX [gemcitabine+oxaliplatin]|COMBINATION_PRODUCT: Tislelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adjuvant Tislelizumab Plus Lenvatinib for Patients at High-risk of HCC Recurrence After Curative Resection or Ablation
Status: NOT_YET_RECRUITING
Conditions: Hepatocellular Carcinoma|Recurrence|Immune Checkpoint Inhibitor
Interventions: DRUG: Adjuvant tislelizumab plus lenvatinib|DRUG: Adjuvant tislelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Relative Patient Benefits of a Hospital-PCMH Collaboration Within an ACO to Improve Care Transitions
Status: COMPLETED
Conditions: Adverse Events|Readmissions|Patient Engagement
Interventions: OTHER: Multi-Model Intensive Discharge Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Study of EC0225 for the Treatment of Refractory or Metastatic Tumors
Status: COMPLETED
Conditions: Cancer
Interventions: DRUG: EC0225, for Injection (Folic acid desacetylvinblastine hydrazide conjugate)|DRUG: 99mTC-EC20 (Folic acid-technetium 99m conjugate)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Two-drug Antibiotic Prophylaxis in Scheduled Cesarean Deliveries
Status: UNKNOWN
Conditions: Endometritis|Cesarean Section; Infection|Wound Infection
Interventions: DRUG: Azithromycin 500 mg|DRUG: Mefoxin 2g
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Single-center Study Evaluating the Safety and Efficacy of Viscogel® as Adjuvant in Act-HIB® Vaccine
Status: COMPLETED
Conditions: Healthy
Interventions: BIOLOGICAL: 0.2μg Act-HIB®|BIOLOGICAL: ViscoGel® and 0.2μg Act-HIB®|BIOLOGICAL: ViscoGel® and 2μg Act-HIB®|BIOLOGICAL: 2μg Act-HIB®|BIOLOGICAL: 10μg Act-HIB®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Minimum Effective Volume of Lidocaine Costoclavicular Brachial Plexus Block
Status: COMPLETED
Conditions: Upper Extremity Surgery
Interventions: OTHER: costoclavicular nerve block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Autonomic Control of the Circulation and VDR
Status: RECRUITING
Conditions: Venous Distension Reflex|Blood Pressure
Interventions: OTHER: Wrist-to-elbow (W-E) occlusion|DRUG: ketorolac tromethamine|DRUG: saline control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Movement Control and Motor Unit Behavior Responses to Different Types of Stimulation
Status: ENROLLING_BY_INVITATION
Conditions: Low Back Pain
Interventions: DEVICE: Transcranial direct current stimulation|DEVICE: Neuromuscular electrical stimulation|OTHER: Motor control exercise|OTHER: Isometric exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Pharmacokinetics/Pharmacodynamics of HSK3486 in Patients With Impairment Renal Functions
Status: COMPLETED
Conditions: Chronic Renal Impairment
Interventions: DRUG: HSK3486
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study of the Effects of Sarcosine on Symptoms and Brain Glycine Levels in People With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DIETARY_SUPPLEMENT: Sarcosine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of a Geriatric Assessment to Plan a Treatment Approach for Older People With Various Blood Disorders
Status: ACTIVE_NOT_RECRUITING
Conditions: Myelodysplastic Syndrome|Myeloproliferative Neoplasms|Chronic Myelomonocytic Leukemia|Atypical Chronic Myeloid Leukemia|Myelodysplastic/Myeloproliferative Overlapping Syndrome
Interventions: OTHER: Geriatric assessment (GA) pre-transplant|DRUG: conditioning regimen|PROCEDURE: Allogeneic CD34+ selected stem cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PRP Effectiveness in Knee Osteoarthritis
Status: UNKNOWN
Conditions: Knee Osteoarthritis
Interventions: OTHER: Intra-articular T-LAB / PRP KIT injection|OTHER: Intra-articular T-LAB / PRP INJECTION SYRINGE injection|OTHER: Intra-articular SALINE injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intravesical Liposomes for Interstitial Cystitis/Painful Bladder Syndrome (IC/PBS)
Status: COMPLETED
Conditions: Interstitial Cystitis|Pelvic Pain
Interventions: BIOLOGICAL: Liposomes
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Trial of Delamanid for 6 Months in Participants With Multidrug-resistant Tuberculosis
Status: COMPLETED
Conditions: Multidrug-resistant Tuberculosis
Interventions: DRUG: Delamanid + OBR|DRUG: Placebo + OBR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of BFH772 in Psoriasis Patients
Status: COMPLETED
Conditions: Psoriasis|Arthritis
Interventions: DRUG: BFH772|DRUG: Placebo|DRUG: BFH772|DRUG: Placebo|DRUG: calcipotriol/betamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of Rituximab Versus Oral Cyclophosphamide to Eradicate or Suppress Autoimmune Anti-Factor VIII Antibodies in Acquired Hemophilia A
Status: TERMINATED
Conditions: Hemophilia A
Interventions: DRUG: Rituxan|DRUG: prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Increasing HAART-Induced Immune Restoration With Cyclosporine
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Abacavir sulfate, Lamivudine and Zidovudine|DRUG: Cyclosporine|BIOLOGICAL: Hepatitis A Vaccine (Inactivated)|DRUG: Efavirenz|BIOLOGICAL: Pneumococcal Conjugate Vaccine, Heptavalent|BIOLOGICAL: Rabies Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of Short-course Radiotherapy Followed by Fruquintinib Plus Sintilimab vs Bevacizumab Plus Capecitabine as First Line Treatment in Advanced mCRC
Status: NOT_YET_RECRUITING
Conditions: CRC|Metastatic Colorectal Cancer|Metastatic Colorectal Adenocarcinoma
Interventions: DRUG: Experimental|DRUG: Active Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preferences & Treatment Satisfaction Drivers in Rosacea Patients
Status: COMPLETED
Conditions: Rosacea
Interventions: DRUG: Azelaic Acid Gel including: Finacea (Azelaic Acid Gel 15%, BAY39-6251)|DRUG: Azelaic Acid Cream|DRUG: Metronidazole gel|DRUG: Metronidazole cream|DRUG: Metronidazole Emulsion|DRUG: Metronidazole Lotion|DRUG: Brimonidine Tartrate Gel
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Vitamin D Treatment and Hypogonadism in Men
Status: COMPLETED
Conditions: Hypogonadism
Interventions: DRUG: Vitamin D supplementation in hypogonadal men|DRUG: Vitamin D supplementation in eugonadal men|DRUG: Placebo hypogonadal|DRUG: Placebo eugonadal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Curcumin on the Clinical Outcome of Pediatric Patients With Active Lupus Nephritis
Status: RECRUITING
Conditions: Lupus Nephritis|SLE Nephritis
Interventions: DRUG: Curcumin Oral Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SafeMedWaste At-Home, Environmentally-Friendly Opioid Disposal Kit for Orthopedic Post-Operative Surgical Patients to Reduce Opioids Available for Diversion
Status: NOT_YET_RECRUITING
Conditions: Opioid Use Disorder
Interventions: DEVICE: SafeMedWaste
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Four-way Crossover, Single and Repeat Dose Study to Determine the Dose Proportionality and Absolute Bioavailability of Fluticasone Furoate Inhalation Powder Administered by Novel Dry Powder Inhaler (NDPI)
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: FF, 50 mcg|DRUG: FF, 100 mcg|DRUG: FF, 200 mcg|DRUG: FF, 250 mcg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Insulin Aspart vs. Human Insulin During Pregnancy by Women With Type 1 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 1
Interventions: DRUG: human insulin|DRUG: insulin aspart
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of 2 Doses of MAP0010 in Adult Asthmatics
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: MAP0010 low dose|DRUG: MAP0010 high dose|DRUG: Budesonide inhalation suspension 0.25mg|DRUG: Budesonide inhalation suspension 0.5mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bronchiolitis Recovery and the Use of High Efficiency Particulate Air (HEPA) Filters
Status: COMPLETED
Conditions: Bronchiolitis
Interventions: OTHER: Winix 5500-2 HEPA filtration units
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Enterobacteriaceae Producing Extended-spectrum β-lactamases (ESBL) Decolonization Study
Status: COMPLETED
Conditions: Enterobacteriaceae Infections
Interventions: DRUG: Decolonization|DRUG: Placebo (Decolonization)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study in Healthy Volunteers to Investigate the Effects of Rifampin on the Pharmacokinetics of NKTR-118
Status: COMPLETED
Conditions: Drug Induced Constipation
Interventions: DRUG: NKTR-118|DRUG: Rifampin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Safety Morus Alba L. Extract on Improvement of Blood Flow
Status: UNKNOWN
Conditions: Blood Flow
Interventions: DIETARY_SUPPLEMENT: Morus Alba L. Extract|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Repeated Controlled Human Schistosoma Mansoni Infection
Status: COMPLETED
Conditions: Schistosomiasis|Schistosoma Mansoni
Interventions: BIOLOGICAL: Schistosoma mansoni infection|BIOLOGICAL: Placebo mock infection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Self-modulated Functional Electrical Stimulation in Chronic Stroke Patients With Severe and Moderate Upper Limb Paresis
Status: TERMINATED
Conditions: Stroke Rehabilitation
Interventions: DEVICE: Self-modulated functional electrical stimulation (SM-FES)|OTHER: Standard Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Monoclonal CGRP Antibodies for Migraine Prevention - a Nationwide Real Life Study
Status: RECRUITING
Conditions: Migraine|Migraine With Aura|Migraine Without Aura|Chronic Migraine|Episodic Migraine
Interventions: DRUG: Erenumab|DRUG: Fremanezumab|DRUG: Galcanezumab
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase Ib Dose Escalation Study of the Combination of LEE011 With Letrozole and Dose Expansion of LEE011 With Hormonal Therapy for the Treatment of Pre-(With Goserelin) and Postmenopausal Women With Hormone Receptor Positive, HER2-negative, Advanced Breast Cancer
Status: COMPLETED
Conditions: Hormone Receptor Positive, HER2-negative, Advanced Breast Cancer
Interventions: DRUG: LEE011|DRUG: Letrozole|DRUG: Tamoxifen|DRUG: Fulvestrant|DRUG: goserelin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Broccoli Sprout on Blood Levels of Sulforaphane to Reduce Responsiveness of Immune System
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DIETARY_SUPPLEMENT: Brocco-sprout homogenate|DIETARY_SUPPLEMENT: Alfalfa sprout homogenate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Short-term and Long-term Outcomes of Colorectal Cancer Treated With Natural Orifice Specimen Extraction Surgery : a National Registry-based Study
Status: RECRUITING
Conditions: Colorectal Cancer
Interventions: PROCEDURE: Natural orifice specimen extraction
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of QAX576 in Patients With Eosinophilic Esophagitis
Status: COMPLETED
Conditions: Eosinophilic Esophagitis
Interventions: DRUG: QAX576 placebo|DRUG: QAX576
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Safety and Efficacy Study of a Range of Linaclotide Doses Administered Orally to Children Ages 6-17 Years Who Fulfill Modified Rome III Criteria for Child/Adolescent Functional Constipation (FC)
Status: COMPLETED
Conditions: Functional Constipation in Children Ages 6-17 Years
Interventions: DRUG: Placebo|DRUG: LIN Dose A|DRUG: LIN Dose B|DRUG: LIN Dose C|DRUG: LIN 145 µg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Preventing Pulmonary Complications in Surgical Patients at Risk of COVID-19
Status: NOT_YET_RECRUITING
Conditions: Pulmonary Complications in Surgical Patients|COVID|Severe Acute Respiratory Syndrome
Interventions: DRUG: RESP301
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Hematoma Block for Reduction of Distal Radius Fractures
Status: COMPLETED
Conditions: Fractures of the Distal Radius
Interventions: DRUG: Lidocaine HCl 2% .|DRUG: Lidocaine HCl 1%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Trial for Pharmacogenomics-based Tuberculosis Therapy (RT-PGTT)
Status: COMPLETED
Conditions: Pulmonary Tuberculosis
Interventions: DRUG: Isoniazid|DRUG: isoniazed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasonic Markers for Myocardial Fibrosis and Prognosis in Aortic Stenosis
Status: COMPLETED
Conditions: Aortic Valve Stenosis|Myocardial Fibrosis
Interventions: DIAGNOSTIC_TEST: Echocardiography|DIAGNOSTIC_TEST: MRI|DIAGNOSTIC_TEST: Blood test|DIAGNOSTIC_TEST: ECG and Holter-ECG|DIAGNOSTIC_TEST: 6 min walking test
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Liposomal Bupivacaine for Post Operative Pain After Knee Replacement Surgery
Status: COMPLETED
Conditions: Post-operative Pain
Interventions: DRUG: Liposome Bupivacaine|DRUG: Bupivacaine HCl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Meclofenamate in Subjects With Recurrent or Progressive Brain Metastasis From Solid Tumor Primary
Status: ACTIVE_NOT_RECRUITING
Conditions: Recurrent Brain Metastases|Progressive Brain Metastases
Interventions: DRUG: Meclofenamate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Influence of Statins and Proton Pump Inhibitors on Clopidogrel Antiplatelet Effects
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DRUG: Rosuvastatin-omeprazole|DRUG: Rosuvastatin-pantoprazole|DRUG: Rosuvastatin-esomeprazole|DRUG: Rosuvastatin-ranitidine|DRUG: Atorvastatin-omeprazole|DRUG: Atorvastatin-pantoprazole|DRUG: Atorvastatin-esomeprazole|DRUG: Atorvastatin-ranitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Equetro for the Treatment of Mania in Children Ages 6-12 With Bipolar Disorder
Status: COMPLETED
Conditions: Bipolar Disorder|Mania
Interventions: DRUG: carbamazepine ER (Equetro)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Blood Components as Probable Prognostic and Predictive Markers of Response to Treatment in Advanced Colon and Rectal Cancers
Status: UNKNOWN
Conditions: Colon Cancer Stage IIb|Rectum Cancer, Adenocarcinoma|Colon Cancer Stage IIIa|Colon Cancer Stage IIIc|Colon Cancer Stage IIIb
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Ketamine Versus Dexmedetomidine With Local Anesthetic in TAP Block
Status: COMPLETED
Conditions: Postoperative Analgesia|Lower Abdominal Cancer
Interventions: DRUG: Ketamine|DRUG: dexmedetomidine|DRUG: control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Deferasirox-AmBisome Therapy for Mucormycosis (DEFEAT Mucor) Study
Status: COMPLETED
Conditions: Mucormycosis
Interventions: DRUG: deferasirox|DRUG: Placebo|DRUG: Liposomal amphotericin B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Biphasic Remogliflozin Etabonate in the Treatment of Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus|Diabetes Mellitus, Type 2
Interventions: DRUG: Biphasic Remogliflozin Etabonate|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant HS-10296 (Almonertinib) Therapy for Potential Resectable Stage III EGFR Mutation-Positive Non-small Cell Lung Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-small Cell Lung Cancer Stage III
Interventions: DRUG: HS-10296 (Almonertinib)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SALT - Success of Active Versus Passive Lead Fixation of Atrial Pacing/Sensing Electrodes
Status: SUSPENDED
Conditions: Bradycardia
Interventions: DEVICE: FineLine II Sterox, FineLine II Sterox, FineLine II Sterox EZ
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Role of Ambulatory Oxygen in Improving the Effectiveness of Pulmonary Rehabilitation for COPD Patients
Status: TERMINATED
Conditions: Chronic Obstructive Pulmonary Diseases
Interventions: OTHER: Pulmonary Rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dose Escalation/Expansion Study of PT199 (an Anti-CD73 mAb) Administered Alone and in Combination With a PD-1 Inhibitor (the MORNINGSTAR Study)
Status: RECRUITING
Conditions: Non Small Cell Lung Cancer|Pancreatic Ductal Adenocarcinoma
Interventions: DRUG: PT199|DRUG: Tislelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Soft Tissue Profile Following Socket Preservation With Platelet Rich Fibrin Versus Free Gingival Graft
Status: UNKNOWN
Conditions: Soft Tissue Mass
Interventions: OTHER: platelet rich fibrin|OTHER: Free gingival graft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Paclitaxel With / Without GW572016 (Lapatinib) As First Line Therapy For Women With Advanced Or Metastatic Breast Cancer
Status: COMPLETED
Conditions: Neoplasms, Breast
Interventions: DRUG: Paclitaxel|DRUG: GW572016 (Lapatinib)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing Two Treatments for Infants With Hydrocephalus
Status: COMPLETED
Conditions: Hydrocephalus
Interventions: PROCEDURE: Endoscopic Third Ventriculostomy|PROCEDURE: CSF Shunt Insertion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Unstable Shoes for Instability and Lumbopelvic Pain
Status: COMPLETED
Conditions: Lumbopelvic Postpartum Pain
Interventions: OTHER: Use unstable shoes Masai Barefoot Technology (MBT)|OTHER: Use conventional sport shoes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of High Dose Fish Oil Supplementation on Delayed Onset Muscle Soreness and Inflammatory Markers
Status: COMPLETED
Conditions: Muscle Damage|Muscle Inflammation
Interventions: DRUG: Lovaza (omega-3-acid ethyl esters)|DRUG: Wheat Germ Oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Bioequivalence Study of Docetaxel for Injectable Emulsion (ANX-514) in Patients With Advanced Cancer
Status: COMPLETED
Conditions: Advanced Cancer
Interventions: DRUG: ANX-514|DRUG: docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single-arm, Single-center, Exploratory Phase II Clinical Study of Envafolimab Combined With Chemoradiotherapy in the Treatment of Locally Advanced pMMR/MSS Rectal Cancer
Status: RECRUITING
Conditions: Envafolimab Combined With Chemoradiotherapy in the Treatment of Locally Advanced pMMR/MSS Rectal Cancer
Interventions: DRUG: Envafolimab combined with chemoradiotherapy in the whole course of neoadjuvant therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigation of the Acute Effects of Percussive Massage Treatment and Stretching Exercise on Balance and Performance
Status: COMPLETED
Conditions: Sports Physical Therapy
Interventions: OTHER: Percussive Massage Group|OTHER: Dynamic stretching group|OTHER: Static stretching group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: 20- Versus 23- Gauge System for Pars Plana Vitrectomy
Status: COMPLETED
Conditions: Diabetic Retinopathy|Macular Edema|Postoperative Complications|Vitreous Hemorrhage
Interventions: DEVICE: 20- and 23 gauge vitreoretinal surgery systems
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Metformin and Prevention of Cardiovascular Events in Patients With Acute Myocardial Infarction and Prediabetes (MIMET)
Status: RECRUITING
Conditions: PreDiabetes|Acute Myocardial Infarction|Non ST Elevation Myocardial Infarction|ST Elevation Myocardial Infarction
Interventions: DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Provex CV Supplement to Reduce Inflammation Cytokines and Blood Pressure
Status: COMPLETED
Conditions: Blood Pressure
Interventions: DRUG: Provex CV|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Theophylline Treatment for Pseudohypoparathyroidism - Children 2-12 Years Old
Status: RECRUITING
Conditions: Pseudohypoparathyroidism|Albright Hereditary Osteodystrophy|Pseudohypoparathyroidism Type 1a
Interventions: DRUG: Theophylline|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Curettage Versus Excision in Nodular and Superficial Basal Cell Carcinomas
Status: SUSPENDED
Conditions: Carcinoma, Basal Cell
Interventions: PROCEDURE: Curettage|PROCEDURE: Deep excision|PROCEDURE: Shave excision|PROCEDURE: Curettage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Decitabine and Vorinostat Conditioning Followed by CD3-/CD19- NK Cells Infusion for High Risk Myelodysplastic Syndromes
Status: COMPLETED
Conditions: Myelodysplastic Syndrome
Interventions: DRUG: Decitabine|DRUG: Vorinostat|BIOLOGICAL: Interleukin-2|OTHER: Natural killer (NK) cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Studies of Kidney Transplant Outcome
Status: COMPLETED
Conditions: Transplant Recipient (Kidney)|Steroid-Free Maintenance Immunosuppression|Post-Transplant Infections|Thymoglobulin
Interventions: DRUG: Steroid-Free Maintenance Immunosuppression|OTHER: Infection After Kidney Transplantation|DRUG: Evaluation of the DGF nomogram in Thymoglobulin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase 2, Safety and Efficacy of Bemnifosbuvir (BEM) and Ruzasvir (RZR) in Subjects With Chronic HCV
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Hepatitis C Virus|Hepatitis C, Chronic|Hepatitis C|Hepatic Cirrhosis|HCV
Interventions: DRUG: Bemnifosbuvir|DRUG: Ruzasvir
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Impact of Germanium-Embedded Knee Brace on Patient Recovery After Knee Arthroscopy
Status: UNKNOWN
Conditions: Knee Arthroscopy|Knee Arthropathy Associated With Other Conditions
Interventions: OTHER: Incrediwear Germanium-Embedded Knee Brace following Knee Arthroscopy|OTHER: Replica Knee Brace
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT