pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Oxaloacetate for the Improvement of Cognitive Complaints in Stage 0-IIIA Breast Cancer Survivors
Status: RECRUITING
Conditions: Anatomic Stage 0 Breast Cancer AJCC v8|Anatomic Stage I Breast Cancer AJCC v8|Anatomic Stage IA Breast Cancer AJCC v8|Anatomic Stage IB Breast Cancer AJCC v8|Anatomic Stage II Breast Cancer AJCC v8|Anatomic Stage IIA Breast Cancer AJCC v8|Anatomic Stage IIB Breast Cancer AJCC v8|Anatomic Stage IIIA Breast Cancer AJCC v8|Early-Stage Breast Carcinoma|Prognostic Stage 0 Breast Cancer AJCC v8|Prognostic Stage I Breast Cancer AJCC v8|Prognostic Stage IA Breast Cancer AJCC v8|Prognostic Stage IB Breast Cancer AJCC v8|Prognostic Stage II Breast Cancer AJCC v8|Prognostic Stage IIA Breast Cancer AJCC v8|Prognostic Stage IIB Breast Cancer AJCC v8|Prognostic Stage IIIA Breast Cancer AJCC v8
Interventions: DRUG: Anhydrous Enol-oxaloacetate|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: AK104 in Combination With AK112 Plus Chemotherapy(SOX/XELOX) as First-line Treatment for Advanced G/GEJ Cancer
Status: RECRUITING
Conditions: Gastric Adenocarcinoma|Gastroesophageal Junction Adenocarcinoma
Interventions: BIOLOGICAL: Cadonilimab|BIOLOGICAL: Ivonescimab|DRUG: XELOX|DRUG: SOX
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bone Marrow Transplant in Treating Patients With Hematologic Cancers
Status: COMPLETED
Conditions: Chronic Myeloproliferative Disorders|Leukemia|Multiple Myeloma and Malignant Plasma Cell Neoplasms|Myelodysplastic Syndromes|Myelodysplastic/Myeloproliferative Neoplasms
Interventions: DRUG: busulfan|DRUG: Cyclophosphamide|DRUG: VP-16|RADIATION: Fractionated Total Body Irradiation (FTBI)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: National Evaluation of Quality of Childcare (C0682)
Status: COMPLETED
Conditions: Child Rearing|Mental Health Wellness 1|Health Behavior
Interventions: BEHAVIORAL: Promotores Training|BEHAVIORAL: Delayed Promotores training|BEHAVIORAL: Caregiver training|BEHAVIORAL: Delayed caregiver training|BEHAVIORAL: Materials support|BEHAVIORAL: Delayed materials support|BEHAVIORAL: Technical assistance|BEHAVIORAL: Delayed technical assistance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Mitigation of Major Hip Injury Due to Fall With a Smart Belt
Status: COMPLETED
Conditions: Hip Injuries|Fractures, Hip|Fall Injury|Fall Risk|Osteoporosis|Osteoporosis Risk
Interventions: DEVICE: Tango Belt
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study in China Evaluating the Safety and Efficacy of Adding Sitagliptin to Stable Therapy With Insulin With or Without Metformin in Participants With Type 2 Diabetes Mellitus (T2DM) (MK-0431-254)
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Sitagliptin|DRUG: Placebo|BIOLOGICAL: Insulin|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: NOX-A12 in Combination With Bendamustine and Rituximab in Relapsed Chronic Lymphocytic Leukemia (CLL)
Status: COMPLETED
Conditions: Chronic Lymphocytic Leukemia
Interventions: DRUG: NOX-A12
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Motion Sensors in Correction Procedures of Long Bone Deformities in the Pediatric Age Group
Status: ACTIVE_NOT_RECRUITING
Conditions: Angulation Deformity of Long Bone (Disorder)|Acquired Deformity of Knee Joint (Disorder)
Interventions: OTHER: Group using traditional method in long bone deformity correction|DEVICE: Group using computer-aided sensors in long bone deformity correction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Absorption, Distribution, Metabolism and Excretion (ADME) Study of TKI258 in Patients With Advanced Solid Malignancies
Status: COMPLETED
Conditions: Advanced Solid Malignancies
Interventions: DRUG: TKI258
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Tremelimumab and Durvalumab With Gem/Cis in Intrahepatic Cholangiocarcinoma
Status: RECRUITING
Conditions: Borderline Resectable Carcinoma|Biliary Tract Cancer
Interventions: DRUG: Durvalumab|DRUG: Tremelimumab|DRUG: Gemcitabine|DRUG: Cisplatin|PROCEDURE: Surgical Resection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Intraoperative Arterial Oxygen Pressures on Early Post-Operative Patient and Graft Survival in Living Donor Kidney Transplantation
Status: COMPLETED
Conditions: Kidney Transplant; Complications|Hyperoxia|Graft Dysfunction
Interventions: PROCEDURE: Arterial blood gas samples
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Rebif New Formulation (RNF) Quality of Life (QOL) Study
Status: COMPLETED
Conditions: Relapsing Multiple Sclerosis
Interventions: DRUG: Rebif New Formulation Non Titrated|DRUG: Rebif New Formulation Titrated
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Opioid Sparing Anaesthesia for Prevention of Postoperative Nausea and Vomiting in Laparoscopic Gynecological Surgery
Status: COMPLETED
Conditions: PONV|Opioid Sparing Anaesthesia
Interventions: DRUG: Dexmedetomidine, ketamine and lidocaine|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Oxytocin as Adjunctive Therapy for Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Oxytocin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Evaluate the Efficacy of OC-02 Nasal Spray on Signs and Symptoms of Dry Eye Disease (The PEARL Study)
Status: COMPLETED
Conditions: Dry Eye Disease
Interventions: DRUG: 0.2 % hemigalactarate (0.11% free base) 0.2 % OC-02 Low Dose (1.1 mg/mL)|DRUG: 1.0 % hemigalactarate (0.11% free base) 1.0 % OC-02 Mid Dose (5.5 mg/mL)|DRUG: 2.0 % hemigalactarate (0.11% free base) 2.0 % OC-02 High Dose (11.1 mg/mL)|DRUG: Placebo (vehicle) nasal spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of PD-1 Plus Chemotherapy in Poorly Differentiated Locally Advanced (LA) HNSCC
Status: RECRUITING
Conditions: Head and Neck Squamous Cell Carcinoma
Interventions: DRUG: Pembrolizumab|DRUG: Cisplatin|DRUG: Paclitaxel-albumin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Pork vs. Chicken/Fish in a DASH Diet on Blood Pressure Regulation in Middle Aged and Older Adults
Status: COMPLETED
Conditions: Hypertension|Dyslipidemias
Interventions: BEHAVIORAL: DASH diet counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose Escalation/De-escalation Study of Pre-operative Stereotactic Radiosurgery for Brain Metastases(RAD 1002)
Status: COMPLETED
Conditions: Brain Metastases
Interventions: RADIATION: Stereotactic Radiosurgery (15 Gy)|RADIATION: Stereotactic Radiosurgery (12 Gy)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study to See Whether a Nutritional Supplement is Beneficial for Patients With Pancreatic Cancer
Status: WITHDRAWN
Conditions: Pancreatic Cancer
Interventions: DIETARY_SUPPLEMENT: Nutritional Supplement|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Safety of Molnupiravir (MK-4482) in Non-Hospitalized Adult Participants With COVID-19 (MK-4482-002)
Status: COMPLETED
Conditions: Coronavirus Disease (COVID-19)
Interventions: DRUG: Molnupiravir|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess 18-Methoxycoronaridine (18-MC HCl) in Healthy Volunteers
Status: COMPLETED
Conditions: Addiction
Interventions: DRUG: 18-MC Compound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Short Term Results of Pediatric Septic Hip Arthritis Management in Assiut University Hospitals
Status: NOT_YET_RECRUITING
Conditions: Septic Arthritis
Interventions: PROCEDURE: Surgery of Drainage of septic hip arthritis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intraoperative Ultrasound Guided Compared to Stereotactic Navigated Ventriculoperitoneal Shunt Placement
Status: RECRUITING
Conditions: Ventriculoperitoneal Shunt (VPS)|Hydrocephalus
Interventions: DEVICE: US -G VPS placement, done by BK Medical 5000 US with burr hole probe (type 9063 N11C5S, 11-5 MHz).|DEVICE: Stereotactic navigation for VPS placement (Brainlab Dual Curve System with cranial navigation software version 3.1).
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Nanoliposomal Irinotecan in Head & Neck and Esophagus After Prior Platinum-based Chemotherapy or Chemoradiotherapy
Status: COMPLETED
Conditions: Head & Neck Cancer
Interventions: DRUG: nanoliposomal irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Rigid Functional And Elastic Bandage For Stabilizing Ankle Support During The Member Of The Chute Football
Status: UNKNOWN
Conditions: Female Soccer Athletes
Interventions: OTHER: rigid bandage|OTHER: elastic bands|OTHER: without the use of banding
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: FLOVENT Hydrofluoroalkane (HFA) In 6-12 Month Old Subjects
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: FLOVENT (fluticasone propionate) HFA|DRUG: Placebo HFA
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long-limb or Distal Gastric Bypass for Superobesity - Randomized Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Obesity
Interventions: PROCEDURE: long-limb gastric bypass|PROCEDURE: distal gastric bypass
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Decitabine, Arsenic Trioxide and Ascorbic Acid for Myelodysplastic Syndromes and Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Myelodysplastic Syndromes and Leukemia, Myeloid, Acute
Interventions: DRUG: Arsenic Trioxide|DRUG: Decitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Pharmacokinetics of Dioxidin, Solution for Topical and External Use, 0.25 mg/ml and Dioxidin, Solution for Infusion and External Use, 5 mg/ml in Healthy Volunteers
Status: COMPLETED
Conditions: Infections
Interventions: DRUG: Hydroxymethylquinoxalindioxyde
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Drug-drug Interaction Study Using Rosuvastatin as a Breast Cancer Resistant Protein (Efflux Transporter), Organic Anion-transporting Polypeptide (OATP)1B1, and OATP1B3 (Uptake Transporters) Probe Substrate
Status: COMPLETED
Conditions: Healthy Volunteers|Pharmacokinetics|Drug Interaction
Interventions: DRUG: Rosuvastatin|DRUG: BAY1841788 (ODM-201)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Optimal Recheck Time for Helicobacter Pylori Eradication: A Prospective Randomized Trial
Status: RECRUITING
Conditions: Helicobacter Pylori Eradication
Interventions: DIAGNOSTIC_TEST: HY-IREXB plus carbon 13 breath detector do the breath urea test after eradication at different times
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of Vedolizumab in Adult Participants With Moderate to Severe Crohn's Disease
Status: RECRUITING
Conditions: Crohn's Disease
Interventions: DRUG: Vedolizumab IV|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Acupuncture Treatment as an Adjunctive Therapy After Knee Replacement
Status: COMPLETED
Conditions: Knee Replacement|Acupuncture
Interventions: OTHER: Acupuncture and Usual care|DRUG: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Deksmedetomidine and Remifentanil in Extubation Agitation
Status: UNKNOWN
Conditions: Agitation
Interventions: DRUG: deksmedetomidine|DRUG: Remifentanil|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: THE EFFECTS OF PREVENTION PROGRAM ON LOW BACK PAIN AND QUALITY OF LIFE DURING PREGNANCY
Status: COMPLETED
Conditions: Low Back Pain|Pregnancy Related|Nurse's Role
Interventions: BEHAVIORAL: Low Back Pain Prevention and Coping Support Program Training in Pregnancy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of the Safety of Subcutaneously Administered Trastuzumab (Herceptin) in Participants With Early and Locally Advanced Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Doxorubicin|DRUG: Docetaxel|DRUG: Paclitaxel|DRUG: Trastuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Effect of Dipyrone, Ibuprofen, Paracetamol and Parecoxib on the Platelet Aggregation in Analgetic Dosages
Status: COMPLETED
Conditions: Platelet Aggregation
Interventions: DRUG: dipyrone|DRUG: Ibuprofen|DRUG: Acetaminophen|DRUG: Acetaminophen|DRUG: Parecoxib/Valdecoxib|OTHER: Blood samples
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Immunogenicity and Safety of a Single 0.5 mL Dose of Inflexal V With a 0.25 mL 2-dose Regimen of Inflexal V
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Inflexal V|BIOLOGICAL: Inflexal V
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Subacromial Impingement Syndrome: Vojta Therapy vs Standard Treatment
Status: COMPLETED
Conditions: Subacromial Impingement Syndrome|Vojta Therapy
Interventions: PROCEDURE: Vojta therapy after standard therapy|PROCEDURE: Standard therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Family Matters Intervention
Status: ENROLLING_BY_INVITATION
Conditions: Childhood Obesity
Interventions: BEHAVIORAL: In-home Visits and Food Preparation Activities|BEHAVIORAL: Ecological Momentary Intervention|BEHAVIORAL: Feedback on Video-recorded Family Meals|BEHAVIORAL: Maintenance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Music Therapy Protocols for Burn Debridement
Status: COMPLETED
Conditions: Pain Management
Interventions: BEHAVIORAL: Music-Based Imagery (MBI)|BEHAVIORAL: Music Alternate Engagement (MAE)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: TRIal evalUating the Menstrual and Ovarian Function of Young Breast Cancer Patients Treated With a cycloPHosphamide-free Regimen
Status: WITHDRAWN
Conditions: Breast Cancer
Interventions: DRUG: Doxorubicin|DRUG: paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fitt's Law MI Experiment
Status: UNKNOWN
Conditions: Healthy
Interventions: BEHAVIORAL: Real execution of Fitts's law tasks|BEHAVIORAL: Motor imagery of Fitts's law tasks|BEHAVIORAL: Skip counting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Tebentafusp Regimen Versus Investigator's Choice in Previously Treated Advanced Melanoma (TEBE-AM)
Status: RECRUITING
Conditions: Advanced Melanoma
Interventions: DRUG: Tebentafusp|DRUG: Tebentafusp with Pembrolizumab|DRUG: Investigators Choice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Efficacy and Safety of Aspirin in Combination With Trametinib and Dabrafenib
Status: NOT_YET_RECRUITING
Conditions: NSCLC|BRAF V600E Mutation|Advanced Cancer|Stage IIIB NSCLC|Stage IV NSCLC
Interventions: DRUG: Combind asprin with Trametinib and Dabrafenib
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Environmental Treatment for Seasonal Affective Disorder (SAD)
Status: COMPLETED
Conditions: Seasonal Affective Disorder
Interventions: DEVICE: Litebook treatment devices|DEVICE: Inactivated negative ion generator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clonal Deletion on Living-Relative Donor Kidney Transplantation
Status: UNKNOWN
Conditions: Renal Transplantation|Uremia
Interventions: PROCEDURE: donor specific transfusion|DRUG: MMF, Bortezomib|PROCEDURE: drugs added according to the immuno condition of the recipients
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety, Tolerability and Efficacy of AK3280 Cream on Hypertrophic Scar
Status: UNKNOWN
Conditions: Hypertrophic Scar
Interventions: DRUG: AK3280 Cream|DRUG: Placebo cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: 'Low-salt' Bread as a Means of Reducing Dietary Salt and Lowering Blood Pressure
Status: COMPLETED
Conditions: Elevated Blood Pressure
Interventions: OTHER: Usual-salt diet|OTHER: Reduced-salt diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluate the Efficacy and Safety of DHA in the Adjuvant Treatment of Children With ASD.
Status: COMPLETED
Conditions: ASD
Interventions: DIETARY_SUPPLEMENT: EuPoly-3 DHA Infant|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: 6-Hydroxymethylacylfulvene in Treating Patients With Refractory Myelodysplastic Syndrome, Acute Myeloid Leukemia, Acute Lymphocytic Leukemia, or Blastic Phase Chronic Myelogenous Leukemia
Status: COMPLETED
Conditions: Leukemia|Myelodysplastic Syndromes
Interventions: DRUG: irofulven
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Ivabradine on Levcromakalim-Induced Symptoms in Individuals With Migraine Without Aura (ILIM)
Status: RECRUITING
Conditions: Headache|Migraine Without Aura
Interventions: DRUG: Levcromakalim|DRUG: Ivabradine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Assessment of the Effects of Different Implant Abutment Occluding Materials on Dental Implant Health Parameters and Microbiology
Status: COMPLETED
Conditions: Peri-Implantitis|Dental Implant Failed|Dental Implant Failure Nos
Interventions: DEVICE: Cotton Pellet|DEVICE: Polytetrafluoroethylene Tape|DEVICE: Synthetic Foam|DEVICE: Polyvinylsiloxane
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Hypothermia Risk Prediction Combined With Active Insulation Management in Geriatric Surgery
Status: UNKNOWN
Conditions: Hypothermia; Anesthesia|Body Temperature Changes
Interventions: DEVICE: IOB Warming Unit (WU505) + Inflatable Warming Blanket|DEVICE: cover with a quilt from the neck to both feet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Risk of Hepatocellular Carcinoma in Patients Treated With ETV vs TDF for Chronic Hepatitis B With Compensated Cirrhosis
Status: UNKNOWN
Conditions: Hepatitis B, Chronic|Hepatocellular Carcinoma|Compensated Cirrhosis
Interventions: DRUG: Entecavir|DRUG: Tenofovir Disoproxil
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Does Increasing Oxygen Nurture Your Symptomatic Ischemic Ulcer Sufficiently?
Status: RECRUITING
Conditions: Peripheral Vascular Disease|Diabetic Foot Ulcer|Amputation
Interventions: DRUG: Hyperbaric oxygen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Characterization of the Essure System Tubal Sterilization Using Ultrasound and X-Ray
Status: COMPLETED
Conditions: Tubal Sterilization
Interventions: PROCEDURE: Micro-insert hysteroscopic sterilization|RADIATION: Plain abdominal Xray|PROCEDURE: Pelvic Ultrasound|RADIATION: Hysterosalpingogram
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Adoptive Cell Therapy of Autologous TIL and PD1-TIL Cells for Patients With Glioblastoma Multiforme
Status: UNKNOWN
Conditions: Glioblastoma Multiforme
Interventions: DRUG: TIL|DRUG: PD1-TIL
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial of Homeopathic Medication TRAUMEEL S for the Treatment of Radiation-Induced Mucositis
Status: COMPLETED
Conditions: Mucositis|Head and Neck Cancer
Interventions: DRUG: Saline|DRUG: Traumeel S|DRUG: Traumeel S|DRUG: Traumeel S
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Nicorandil on Left Ventricular Myocardial Strain in Patients With Coronary Chronic Total Occlusion
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DRUG: nicorandil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: NPC Study : TAX + CIS Neoadjuvant in Patients With Loco Regionally Advanced Undifferentiated Carcinoma of Nasopharyngeal Type (UCNT)
Status: COMPLETED
Conditions: Head and Neck Neoplasms
Interventions: DRUG: DOCETAXEL(XRP6976)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Healthy Volunteer Study to Investigate the Relative Bioavailability of Two Forms of GSK598809 Capsules.
Status: COMPLETED
Conditions: Substance Dependence
Interventions: DRUG: GSK598809 new formulation|DRUG: GSK598809 old formulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neonatal Seizure Registry - Developmental Functional EValuation
Status: ACTIVE_NOT_RECRUITING
Conditions: Neonatal Seizure|Hypoxic-Ischemic Encephalopathy|Stroke|Intracranial Hemorrhages|Epilepsy|Cerebral Palsy|Intellectual Disability
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Nasaleze on Nasal Challenge With Allergen
Status: TERMINATED
Conditions: Allergic Rhinitis
Interventions: DRUG: Nasaleze Spray|OTHER: Placebo spray|BIOLOGICAL: Allergen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ipilimumab With or Without Talimogene Laherparepvec in Unresected Melanoma
Status: COMPLETED
Conditions: Melanoma
Interventions: DRUG: Talimogene laherparepvec|DRUG: Ipilimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pharmacokinetic Study to Compare Sustained Release and Standard Paracetamol Formulations.
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Paracetamol 500 mg|DRUG: Paracetamol 1000 mg|DRUG: Paracetamol 750 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Acute Effect of Aerobic Exercise on Sleep in Patients With Depression
Status: COMPLETED
Conditions: Depression|Sleep|Sleep Disorder|Sleep Disturbance|Sleep Fragmentation|Sleep Initiation and Maintenance Disorders|Insomnia|Insomnia, Psychophysiological|Insomnia Due to Other Mental Disorder|Insomnia Related to Another Mental Condition
Interventions: BEHAVIORAL: Aerobic exercise, bicycle ergometer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Cebranopadol for the Treatment of Acute Pain After Abdominoplasty
Status: NOT_YET_RECRUITING
Conditions: Acute Pain
Interventions: DRUG: Cebranopadol|DRUG: Cebranopadol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Optimizing Acquisition Parameters and Interpretive Methods of FDG-PET/CT With Rb-82
Status: COMPLETED
Conditions: Sarcoidosis
Interventions: DRUG: Fluorodeoxyglucose|DRUG: Rubidium|DIAGNOSTIC_TEST: FDG-PET/CT with Rb82 Myocardial Perfusion Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation of the Treatment of Adipose Tissue With Liposonix System (Model 2) Using a New Treatment Method
Status: COMPLETED
Conditions: Subcutaneous Adipose Tissue
Interventions: DEVICE: Liposonix System (Model 2)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: XK469R in Treating Patients With Refractory Hematologic Cancer
Status: COMPLETED
Conditions: Adult Acute Basophilic Leukemia|Adult Acute Eosinophilic Leukemia|Adult Acute Megakaryoblastic Leukemia (M7)|Adult Acute Minimally Differentiated Myeloid Leukemia (M0)|Adult Acute Monoblastic Leukemia (M5a)|Adult Acute Monocytic Leukemia (M5b)|Adult Acute Myeloblastic Leukemia With Maturation (M2)|Adult Acute Myeloblastic Leukemia Without Maturation (M1)|Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities|Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)|Adult Acute Myeloid Leukemia With t(16;16)(p13;q22)|Adult Acute Myeloid Leukemia With t(8;21)(q22;q22)|Adult Acute Myelomonocytic Leukemia (M4)|Adult Erythroleukemia (M6a)|Adult Pure Erythroid Leukemia (M6b)|Blastic Phase Chronic Myelogenous Leukemia|Chronic Myelomonocytic Leukemia|de Novo Myelodysplastic Syndromes|Previously Treated Myelodysplastic Syndromes|Recurrent Adult Acute Lymphoblastic Leukemia|Recurrent Adult Acute Myeloid Leukemia|Refractory Anemia With Excess Blasts|Refractory Anemia With Excess Blasts in Transformation|Refractory Chronic Lymphocytic Leukemia|Relapsing Chronic Myelogenous Leukemia|Secondary Myelodysplastic Syndromes|Stage III Chronic Lymphocytic Leukemia|Stage IV Chronic Lymphocytic Leukemia|Untreated Adult Acute Myeloid Leukemia
Interventions: DRUG: R(+)XK469|OTHER: pharmacological study|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dispensing Study to Assess Visual Performance of Prototype Contact Lenses
Status: COMPLETED
Conditions: Presbyopia|Refractive Error
Interventions: DEVICE: Etafilcon A, Lotrafilcon B , Senofilcon A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of Food on the Bioavailability of 30 mg Estetrol (E4) Tablet in Healthy Postmenopausal Female Volunteers
Status: COMPLETED
Conditions: Food-effect
Interventions: DRUG: 30 mg estetrol (E4)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Adebrelimab, Camrelizumab Plus Apatinib as First-line Therapy in Patients With Advanced Hepatocellular Carcinoma
Status: RECRUITING
Conditions: Advanced Hepatocellular Carcinoma
Interventions: DRUG: adebrelimab, camrelizumab plus apatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Conventional Vaccine and Intradermal Vaccine Among HIV-infected Young Subjects
Status: COMPLETED
Conditions: Human Influenza
Interventions: BIOLOGICAL: Agripal|BIOLOGICAL: IDflu9μg|BIOLOGICAL: IDflu15μg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Implementing a Home Blood Pressure Monitoring Program in Primary Care
Status: RECRUITING
Conditions: Hypertension
Interventions: BEHAVIORAL: Supported HBPM program plus multifaceted implementation strategy|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effects of Ping-Shuai-Gong and Arm-Swing-Exercise
Status: COMPLETED
Conditions: Effects of; Movement|Inactivity, Physical|Degeneration
Interventions: BEHAVIORAL: Low intensity exercise - Ping-Shuai Gong (PSG)|BEHAVIORAL: Low intensity exercise - Arm-Swing Exercise (ASE)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Acetazolamide or Metolazone in Acute Heart Failure
Status: NOT_YET_RECRUITING
Conditions: Heart Failure Acute|Decompensated Heart Failure
Interventions: DRUG: Acetazolamide 250 MG|DRUG: Metolazone 2.5 MG|DRUG: Furosemide Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Safety and Immunogenicity of mRNA-1273 Vaccine to Prevent COVID-19 in Adult Organ Transplant Recipients and in Healthy Adult Participants
Status: COMPLETED
Conditions: SARS-CoV-2
Interventions: BIOLOGICAL: mRNA-1273
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of IPMN Progression Prevention With Tocotrienol (SIPP-T3)
Status: RECRUITING
Conditions: Neoplasm of Pancreas|IPMN, Pancreatic
Interventions: DRUG: Vitamin E Delta Tocotrienol|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Radiotherapy Combined With ICIs as Treatment for LA-NSCLC After Failing Induction Immunochemotherapy
Status: NOT_YET_RECRUITING
Conditions: Non-small Cell Lung Cancer Stage III
Interventions: RADIATION: radiotherapy|DRUG: Platinum-Based Drug|DRUG: Immunotherapy|DRUG: Immunotherapeutic Agent
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Satiating Effects of Isolated Soy Proteins
Status: COMPLETED
Conditions: Weight Management
Interventions: DIETARY_SUPPLEMENT: Dry-Blended Beverage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Chinese Herb for the Treatment of Depression and Anxiety Disorders
Status: UNKNOWN
Conditions: Depression, Anxiety
Interventions: OTHER: SZ-05|DRUG: Escitalopram Pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Pharmacokinetics of HSK21542 in Subjects With Renal Impairment
Status: RECRUITING
Conditions: Renal Impairment
Interventions: DRUG: HSK21542 Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating Unilateral Deep Brain Stimulation in Patients With Obsessive Compulsive Disorder
Status: COMPLETED
Conditions: Obsessive-Compulsive Disorder
Interventions: DEVICE: Electrical stimulation of the BNST
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cranial Electrotherapy Stimulation in the Treatment of Migraine Headaches
Status: COMPLETED
Conditions: Migraine
Interventions: DEVICE: Cranial Electrostimulator|DEVICE: Sham Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Prospective Monitoring of Non-Vitamin K Oral Anticoagulants in Older Adults With Atrial Fibrillation and Frailty
Status: UNKNOWN
Conditions: Atrial Fibrillation|Frailty|Anticoagulant-induced Bleeding|Stroke
Interventions: DRUG: Warfarin|DRUG: Dabigatran|DRUG: Rivaroxaban|DRUG: Apixaban|DRUG: Edoxaban
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Varenicline for Smoking Cessation in Hospitalized Patients With Psychiatric Disorders
Status: WITHDRAWN
Conditions: Tobacco Use Cessation|Psychiatric Disorders
Interventions: DRUG: Varenicline|DRUG: Nicotine patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Medical Thoracoscopy in Treatment Outcomes of Empyema Management
Status: NOT_YET_RECRUITING
Conditions: Empyema
Interventions: PROCEDURE: Thoracoscopy procedure|PROCEDURE: Chest tube thoracostomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Outcome of Treatment of Traumatised Refugees With Psychotherapy and/or Antidepressants
Status: COMPLETED
Conditions: Post-Traumatic Stress Disorder
Interventions: DRUG: Sertraline|BEHAVIORAL: trauma-focused cognitive behavioural therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anti-CD3 & Anti-CD7 Ricin A Immunotoxin-Combination for Acute Graft Versus Host Disease
Status: WITHDRAWN
Conditions: Acute Graft Versus Host Disease
Interventions: BIOLOGICAL: IT-Combination
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sleep and Depression in Induction of Labour
Status: COMPLETED
Conditions: Prolonged Pregnancy|Sleep Disturbance|Depression
Interventions: OTHER: Intervention for outpatient group was to go home|OTHER: Intervention for inpatient group was to stay at ward
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study of ARV-471 (PF-07850327) Plus Palbociclib Versus Letrozole Plus Palbociclib in Participants With Estrogen Receptor Positive, Human Epidermal Growth Factor Negative Advanced Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: ARV-471 (PF-07850327)|COMBINATION_PRODUCT: Palbociclib|DRUG: Letrozole|COMBINATION_PRODUCT: Palbociclib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioavailability of BIBR 953 ZW Under Influence of Food in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BIBR 1048 MS HPMC capsule|DRUG: BIBR 1048 MS gelatine capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Auburn University Research on Olive Oil for Alzheimer's Disease (AU-ROOAD)
Status: COMPLETED
Conditions: Alzheimer Disease|Cerebral Amyloid Angiopathy
Interventions: OTHER: EVOO|OTHER: OO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Paclitaxel + Trastuzumab + Pertuzumab as Pre-Op for Inflammatory BrCa
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Trastuzumab|DRUG: Pertuzumab|DRUG: Paclitaxel|DRUG: Doxorubicin|DRUG: Cyclophosphamide|PROCEDURE: Mastectomy|RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Intravenous Corticosteroid Injections on Dysphagia After Cervical Spine Surgery
Status: TERMINATED
Conditions: Dysphagia After Anterior Cervical Decompression and Fusion of the Spine
Interventions: DRUG: Dexamethasone|OTHER: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Endoscopic Fundoplication Versus Proton Pump Inhibitors for GERD Treatment
Status: TERMINATED
Conditions: Gastroesophageal Reflux Disease (GERD)
Interventions: PROCEDURE: Transoral Incisionless Fundoplication|DRUG: Proton Pump Inhibitors; active control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evive Health Randomized Controlled Trials
Status: COMPLETED
Conditions: People Due for Mammogram|People Due for Colonoscopy|People Due for Blood Pressure Test|People Due for Cholesterol Test
Interventions: BEHAVIORAL: Control|BEHAVIORAL: Curiosity|BEHAVIORAL: Curiosity linked to Action
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Patient-centered Information on Permanent Contraception
Status: RECRUITING
Conditions: Contraception|Reproductive Behavior|Contraception Behavior
Interventions: BEHAVIORAL: Control arm: Existing educational website|BEHAVIORAL: Advancing Access Website
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Study to Assess YH002 in Combination With YH001 in Subjects With Advanced Solid Tumors
Status: RECRUITING
Conditions: Advanced Solid Tumor
Interventions: DRUG: A:YH002+YH001|DRUG: B:YH002+YH001|DRUG: YH002+YH001
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: S9926 Temozolomide in Patients With Unresectable/Metastatic Gastrointestinal Stromal Tumors
Status: COMPLETED
Conditions: Gastrointestinal Stromal Tumor
Interventions: DRUG: temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Safety&Efficacy of Repetitive Transcranial Magnetic Stimulation for Post-Stroke Upper Extremity Function Improvement
Status: RECRUITING
Conditions: Stroke
Interventions: DEVICE: rTMS|DEVICE: rTMS|DEVICE: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Rectal Misoprostol in Reducing Intra-operative Blood Loss During Myomectomy
Status: COMPLETED
Conditions: Blood Loss, Surgical|Uterine Myoma
Interventions: DRUG: Misoprostol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Study of Single and Multiple Ascending Doses of JNJ-61393215 in Healthy Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: JNJ-61393215|DRUG: Placebo|DRUG: JNJ-61393215
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Treatment of Diabetes After Gastric Bypass With Sitagliptin
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Sitagliptin phosphate|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Demonstrate the Analgesic Efficacy of Oxycodone/Naloxone Prolonged Release Tablets in Addition to Pregabalin Compared to Pregabalin Alone in Opioid-naïve Subjects Treated With Pregabalin Suffering From Moderate to Severe Pain Due to Diabetic Polyneuropathy
Status: COMPLETED
Conditions: Moderate to Severe Pain Due to Diabetic Polyneuropathy
Interventions: DRUG: Oxycodone Naloxone|DRUG: Placebo tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Evaluate Efficacy and Safety of Zanubrutinib With R-CHOP in Newly Diagnosed Non-GCB DLBCL Patients With Double Expression
Status: ACTIVE_NOT_RECRUITING
Conditions: Diffuse Large B-cell Lymphoma(DLBCL)
Interventions: DRUG: Zanubrutinib + R-CHOP
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prehabilitation in Pancreatic Surgery
Status: RECRUITING
Conditions: Pancreatic Cancer|Periampullary Cancer|Frailty Syndrome|Malnutrition|Perioperative/Postoperative Complications
Interventions: OTHER: Multimodal Prehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety, Tolerability and Blood Sampling of GSK3923868 Administered Via Dry Powder Inhaler to Healthy Participants of Chinese, Japanese and European Ancestry
Status: NOT_YET_RECRUITING
Conditions: Respiratory Tract Infections
Interventions: DRUG: GSK3923868|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Look at and Compare How Inhaled and Intravenous Fluticasone Furoate is Processed by the Body in Healthy Caucasian, Japanese, Korean and Chinese Subjects
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: fluticasone furoate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Evaluation of the Effect of Autologous Fat and SVF Transplantation in Promoting Mechanical-stretch Induced in Vivo Skin Regeneration
Status: UNKNOWN
Conditions: Scar
Interventions: PROCEDURE: FAT-GRAFT|PROCEDURE: SVF-TRANSPLANTATION|PROCEDURE: PLACEBO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Pharmacokinetic Study of MM-302 in Patients With Advanced Breast Cancer
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: DRUG: MM-302 Monotherapy|DRUG: MM-302 in combination with trastuzumab|DRUG: MM-302 in combination with trastuzumab q3w|DRUG: MM-302 in combination with trastuzumab and cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Blood Volume Analysis- Guided Management of Decompensated Heart Failure
Status: COMPLETED
Conditions: Acute Decompensated Heart Failure
Interventions: DIAGNOSTIC_TEST: BVA-100
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ACUTE-Acute Surgical Care- Risk Factors and Outcomes for Patients in Need of Acute Surgical Care
Status: RECRUITING
Conditions: Risk Factors|Complication of Surgical Procedure|Complication of Treatment|Complication of Anesthesia|Long Term Effects After Emergency Surgery|Long Term Effects After GI Bleeding
Interventions: OTHER: Observational study of different treatments and time to treatment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p