pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Effect of Pentoxifylline on Preventing Chemotherapy-induced Mucositis in Patients With Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer Female
Interventions: DRUG: Pentoxifylline|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Altitudes: A Digital Intervention to Support Caregivers
Status: NOT_YET_RECRUITING
Conditions: Care Burden|Care Giving Burden|Caregiver Burnout|Caregiver Stress|Caregiver Wellbeing|Support, Family
Interventions: DEVICE: Device: Altitudes USA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Understanding Mechanisms of Exercise Behavior Change
Status: COMPLETED
Conditions: Overweight and Obesity|Physical Activity|Incentives
Interventions: BEHAVIORAL: self-monitoring|BEHAVIORAL: daily incentives|BEHAVIORAL: delayed lump sum incentives
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Absorption, Metabolism, and Excretion Following a Single Oral Dose of [14C]-Rucaparib
Status: COMPLETED
Conditions: Solid Tumor
Interventions: DRUG: C-14 labeled Rucaparib|DRUG: Rucaparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Financial Incentives and Motivational Intervention to Improve Gastric Cancer Screening in China
Status: NOT_YET_RECRUITING
Conditions: Gastric Cancer
Interventions: OTHER: Financial Incentives|OTHER: Motivational Intervention|OTHER: Mixed Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Onabotulinum Toxin A (Botox) in the Treatment of Transfer Dysphagia
Status: RECRUITING
Conditions: Transfer Dysphagia|Oropharyngeal Dysphagia|Cricopharyngeus Muscle Dysfunction|Dysphagia, Late Effect of Stroke
Interventions: DRUG: Botulinum Toxin Type A Injection [Botox]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cryoballon Versus Radiofrequency Ablation for Persistent Atrial Fibrillation
Status: UNKNOWN
Conditions: Persistent Atrial Fibrillation
Interventions: PROCEDURE: Radiofrequency Ablation|PROCEDURE: Cryoballoon ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Beetroot Juice on Blood Pressure Regulation in Post Menopausal Women
Status: COMPLETED
Conditions: Postmenopausal Women
Interventions: DRUG: Beetroot juice|DRUG: Beetroot juice placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Treatment of Atrial Fibrillation in Patients by Pulmonary Vein Isolation in Combination With Renal Denervation or Pulmonary Vein Isolation Only
Status: COMPLETED
Conditions: Paroxysmal Atrial Fibrillation|Persistent Atrial Fibrillation|Out of Range Hypertension|Signs of Sympathetic Overdrive
Interventions: PROCEDURE: procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Synergistic Gut-brain Axis Modulation Via Vagal Stimulation and Cognitive Behavioral Therapy in Functional Dyspepsia
Status: NOT_YET_RECRUITING
Conditions: Functional Dyspepsia
Interventions: DEVICE: taVNS|BEHAVIORAL: CBT|BEHAVIORAL: Education Control|DEVICE: Sham taVNS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sub Lingual Versus Traditional Oral Administration of Ticagrelor in Acute Coronary Syndrome/Non ST-elevation Myocardial Infarction - A Platelet Reactivity Study
Status: COMPLETED
Conditions: Acute Coronary Syndromes|Non ST Elevation Myocardial Infarction
Interventions: DRUG: Sub Lingual Ticagrelor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Two-dose Schedule of Quadrivalent HPV Recombinant Vaccine in 11-year-old Boys in Mexico City
Status: UNKNOWN
Conditions: Human Papilloma Virus
Interventions: BIOLOGICAL: quadrivalent human papillomavirus (types 6, 11, 16,18) recombinant vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of MEDI1191 in Sequential and Concurrent Combination With Durvalumab in Subjects With Advanced Solid Tumors
Status: COMPLETED
Conditions: Solid Tumors|Cancer
Interventions: BIOLOGICAL: MEDI1191|BIOLOGICAL: Durvalumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Self Collected Sampling in Non-attendees Cervical Cancer Screening: DNA Test and Molecular Triage for HPV Positive Women
Status: UNKNOWN
Conditions: Cervical Cancer
Interventions: DEVICE: Self sampling device|OTHER: Cervical ThinPrep sampling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: |Primary Purpose: SCREENING
Clinical trial: Myocardial Hybrid Revascularization Versus Coronary artERy Bypass GraftING for Complex Triple-vessel Disease
Status: UNKNOWN
Conditions: Multivessel Coronary Artery Disease
Interventions: PROCEDURE: Hybrid Revascularization|PROCEDURE: Conventional Coronary Artery Bypass Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Treatment With Sertraline for Noncardiac Chest Pain
Status: COMPLETED
Conditions: Panic Attacks|Chest Pain|Depression
Interventions: DRUG: sertraline|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Subcutaneous Daptomycin in Healthy Volunteers (DAPTOSC)
Status: COMPLETED
Conditions: Antibiotics|Subcutaneous Injection|Daptomycin
Interventions: DRUG: Daptomycin|DRUG: Daptomycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Reduction of Plantar Pressure in Neuropathic Diabetic Foot Patients Using Insoles With Removable Pegs Design
Status: COMPLETED
Conditions: Foot Ulcer, Diabetic
Interventions: OTHER: device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Test How Well Different Doses of BI 3804379 Are Tolerated by Healthy People
Status: NOT_YET_RECRUITING
Conditions: Healthy
Interventions: DRUG: BI 3804379|DRUG: Placebo matching BI 3804379
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study of Hypotensive Hematopoietic Malignancy Patients' USCOM Readings
Status: COMPLETED
Conditions: Leukemia|Lymphoma|Paraproteinemias|Multiple Myeloma|Myelodysplastic Syndromes
Interventions: PROCEDURE: USCOM scan|PROCEDURE: Fluid Bolus
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Efficacy and Safety of Eltrombopag in Lower-risk MDS Patients With Platelet Transfusion Dependence
Status: RECRUITING
Conditions: Myelodysplastic Syndromes
Interventions: DRUG: Eltrombopag|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Gastric Peritoneal Carcinomatosis by Association of Complete Surgical Resection of the Lesions and Intraperitoneal Immunotherapy Using Catumaxomab
Status: TERMINATED
Conditions: Patients With Gastric Peritoneal Carcinomatosis
Interventions: DRUG: Catumaxomab 100µg|DRUG: Catumaxomab 140µg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Perioperative Pain Blocks In Urological Surgery
Status: COMPLETED
Conditions: Pain, Postoperative|Nerve Block|Robotic Surgical Procedures
Interventions: DRUG: Bupivacain|DRUG: Ultrasound-guided transversus abdominus plane block|DRUG: Laparoscopic-guided transversus abdominus plane block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Beneficial Effects of a Protein-rich Breakfast on Appetite Control & Cognition in Overweight and Obese Adolescents
Status: COMPLETED
Conditions: Overweight|Obesity
Interventions: BEHAVIORAL: Breakfast Skipping|BEHAVIORAL: Normal Protein Breakfast Meals|BEHAVIORAL: Protein-rich Breakfast Meals
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Influence of Prior Walking on Postprandial Metabolism in Centrally Obese Men
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Cardiovascular Diseases|Endothelial Dysfunction|Insulin Resistance|Oxidative Stress
Interventions: BEHAVIORAL: Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Ultra Low Dose Orbital Radiation Therapy in Treating Patients With Stage I-IV Indolent B-cell Lymphoma or Mantle Cell Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Ann Arbor Stage I B-Cell Non-Hodgkin Lymphoma|Ann Arbor Stage I Grade 1 Follicular Lymphoma|Ann Arbor Stage I Grade 2 Follicular Lymphoma|Ann Arbor Stage I Indolent Adult Non-Hodgkin Lymphoma|Ann Arbor Stage I Mantle Cell Lymphoma|Ann Arbor Stage II B-Cell Non-Hodgkin Lymphoma|Ann Arbor Stage II Grade 1 Follicular Lymphoma|Ann Arbor Stage II Grade 2 Follicular Lymphoma|Ann Arbor Stage II Indolent Adult Non-Hodgkin Lymphoma|Ann Arbor Stage II Mantle Cell Lymphoma|Ann Arbor Stage III B-Cell Non-Hodgkin Lymphoma|Ann Arbor Stage III Grade 1 Follicular Lymphoma|Ann Arbor Stage III Grade 2 Follicular Lymphoma|Ann Arbor Stage III Indolent Adult Non-Hodgkin Lymphoma|Ann Arbor Stage III Mantle Cell Lymphoma|Ann Arbor Stage IV B-Cell Non-Hodgkin Lymphoma|Ann Arbor Stage IV Grade 1 Follicular Lymphoma|Ann Arbor Stage IV Grade 2 Follicular Lymphoma|Ann Arbor Stage IV Indolent Adult Non-Hodgkin Lymphoma|Ann Arbor Stage IV Mantle Cell Lymphoma|Ocular Adnexal Lymphoma|Ocular Adnexal Mucosa-Associated Lymphoid Tissue Lymphoma|Orbit Lymphoma
Interventions: RADIATION: External Beam Radiation Therapy|DRUG: Orbital Radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adductor Canal Catheter vs Local Infiltration of Analgesia for Total Knee Arthroplasty
Status: WITHDRAWN
Conditions: Acute Pain|Regional Anesthesia Morbidity
Interventions: DRUG: ropivacaine|DRUG: bupivacaine|DEVICE: Sham Adductor Canal Catheter|DEVICE: Adductor Canal Catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Intranasal Oxytocin in Antiosocial Personality Disorder and Psychopathy
Status: COMPLETED
Conditions: Antisocial Personality Disorder
Interventions: DRUG: Oxytocin nasal spray|OTHER: Placebo spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: PKC412, Daunorubicin, and Cytarabine in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Acute Myeloid Leukemia (AML)
Interventions: DRUG: cytarabine|DRUG: daunorubicin hydrochloride|DRUG: midostaurin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Carbidopa-Levodopa in Dry AMD With Geographic Atrophy
Status: TERMINATED
Conditions: Age Related Macular Degeneration
Interventions: DRUG: carbidopa-levodopa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy With or Without Bone Marrow Transplantation in Treating Patients With Acute Lymphoblastic Leukemia
Status: COMPLETED
Conditions: Leukemia|Lymphoma
Interventions: DRUG: asparaginase|DRUG: cyclophosphamide|DRUG: cytarabine|DRUG: daunorubicin hydrochloride|DRUG: dexamethasone|DRUG: doxorubicin hydrochloride|DRUG: leucovorin calcium|DRUG: mercaptopurine|DRUG: methotrexate|DRUG: mitoxantrone hydrochloride|DRUG: prednisolone|DRUG: prednisone|DRUG: therapeutic hydrocortisone|DRUG: vincristine sulfate|PROCEDURE: allogeneic bone marrow transplantation|PROCEDURE: autologous bone marrow transplantation|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Impression & Prosthesis Quality Made From Different Polyvinylsiloxane Impression Techniques
Status: COMPLETED
Conditions: Endodontically Treated Teeth|Missing Teeth|Discoloration, Tooth|Prosthesis Failure, Dental|Open Margin on Tooth Restoration
Interventions: DEVICE: Polyvinylsiloxane impression with different techniques
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Biologic Augment of the Medial Patellofemoral Ligament Following Primary Lateral Patellofemoral Dislocation (BioPPD)
Status: NOT_YET_RECRUITING
Conditions: Patellofemoral Dislocation
Interventions: DEVICE: MPFL repair with Biobrace augmentation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Five-repetition Sit-to-stand Test for Lower Back Pain or Radiculopathy
Status: COMPLETED
Conditions: Degenerative Disc Disease|Degenerative Spondylolisthesis|Herniated Disc|Stenosis, Spinal|Nerve Root Compress;Lumbosac
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: PEN-866 in Patients With Advanced Solid Malignancies
Status: UNKNOWN
Conditions: Carcinoma|Endometrial Adenocarcinoma|Neoplasms|Squamous Cell Carcinoma of the Anus|Adenocarcinoma of the Pancreas|Advanced Cancer|Solid Tumor|Solid Carcinoma|Squamous Cell Carcinoma of the Cervix|Squamous Cell Carcinoma|Squamous Cell Carcinoma of the Vulva|Squamous Cell Carcinoma of the Penis|Gastric Cancer|Gastric Adenocarcinoma|Gastroesophageal Junction Adenocarcinoma|Small-cell Lung Cancer|Small Cell Lung Carcinoma|Pancreatic Ductal Adenocarcinoma|Pancreatic Adenocarcinoma
Interventions: DRUG: PEN-866 Sodium|DRUG: fluorouracil|DRUG: Folinic acid|DRUG: Niraparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Genomic Predictors of Decitabine Response in Patients With Acute Myeloid Leukemia or Myelodysplastic Syndromes
Status: COMPLETED
Conditions: Leukemia, Myeloid, Acute|Myelodysplastic Syndromes
Interventions: DRUG: decitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multicenter, Prospective, RCT：Investigation of Combined Modality Therapy for Locally Advanced Mid/Low Rectal Cancer.
Status: UNKNOWN
Conditions: Rectal Cancer, Adenocarcinoma|Neoadjuvant Chemoradiation
Interventions: OTHER: non-NCRT|OTHER: NCRT|DRUG: capecitabine with oxaliplatin|DRUG: capecitabine|PROCEDURE: TEM|PROCEDURE: radical resection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of a Polymeric Surfactant Technology Cleanser in Sensitive Skin Participants
Status: COMPLETED
Conditions: Dermatitis, Atopic|Rosacea|Acne Vulgaris|Sensitive Skin
Interventions: OTHER: Non-marketed Cosmetic Facial Cleanser
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Comparative Study on Tolerance and Pharmacokinetics of Voriconazole for Injection in Healthy Subjects
Status: COMPLETED
Conditions: Healthy Adults
Interventions: DRUG: 4 mg/kg Voriconazole|DRUG: 6 mg/kg Voriconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Pilot Validation of a Hemodilution Technique to Estimate Blood Volume in Vivo
Status: UNKNOWN
Conditions: Hypovolemia|Hypervolemia
Interventions: DIAGNOSTIC_TEST: Radiodilution via Daxor BVA-100|DIAGNOSTIC_TEST: Hemodilution via hematocrit measurement
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Fractional Concentration of Exhaled NO(FENO) to Direct Montelukast Treatment of Sub-acute Cough
Status: UNKNOWN
Conditions: Coughing
Interventions: DRUG: Montelukast|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Tolerability and Efficacy of Intravitreal LMG324 in the Treatment of Neovascular Age-Related Macular Degeneration
Status: TERMINATED
Conditions: Age-related Macular Degeneration (AMD)
Interventions: BIOLOGICAL: LMG324|BIOLOGICAL: Ranibizumab 0.5 mg|BIOLOGICAL: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Evaluation Of 1.2% Atorvastatin and 1.2% Simvastatin Gel Local Drug Delivery And Redelivery In Chronic Periodontitis Subjects With Diabetes Mellitus: A Randomized Controlled Clinical Trial.
Status: COMPLETED
Conditions: Chronic Periodontitis Wth Diabetes Mellitus
Interventions: DRUG: ATORVASTATIN|DRUG: SIMVASTATIN|DRUG: PLACEBO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: "Liposomal Encapsulated Vitamin C in Complex Regional Pain Syndrome"
Status: COMPLETED
Conditions: Complex Regional Pain Syndrome I of Lower Limb
Interventions: DIETARY_SUPPLEMENT: liposomal vitamin C|DIETARY_SUPPLEMENT: standard vitamin C|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Turkish Version of the Affordance in the Home Environment for Motor Development-Toddler (AHEMD-T)
Status: COMPLETED
Conditions: Musculoskeletal Diseases|Genetic Disease|Metabolic Disease|Delays Developmental
Interventions: OTHER: investigating the psychometric properties of Turkish Affordance in the Home Environment for Motor Development-Toddler (AHEMD-T)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Instrument-assisted Soft Tissue Mobilization Versus Integrated on Mechanical Neck Pain
Status: COMPLETED
Conditions: Non-specific Chronic Mechanical Neck Pain
Interventions: OTHER: instrument assisted soft tissue mobilization|OTHER: integrated neuromuscular inhibition technique|OTHER: conventional therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Analgesia-first Minimal Sedation for Spontaneous Intracerebral Hemorrhage Early Antihypertensive Treatment
Status: COMPLETED
Conditions: Early Systolic Blood Pressure Control Rate|Hematoma Growth|Blood Pressure Variability|Healthcare Worker Satisfaction|Duration of ICU Treatment and Mechanical Ventilation
Interventions: COMBINATION_PRODUCT: Analgesia-first minimal sedation|COMBINATION_PRODUCT: Antihypertensive treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Negative Pressure Wound Therapy as a Drug Delivery System (ADANPWT)
Status: WITHDRAWN
Conditions: Foot Ulcer, Diabetic
Interventions: DEVICE: Quantum™ Therapy - NPWT with Prontosan|DEVICE: Quantum™ Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics and Safety Study of CTAP101 Capsules in Japanese and Non-Japanese Healthy Subjects and Non-Japanese Healthy Subjects
Status: COMPLETED
Conditions: Vitamin D Insufficiency|Secondary Hyperparathyroidism
Interventions: DRUG: CTAP101 Capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluating Mechanisms of Blood Pressure Reduction Using Meditation in Hypertensive African Americans
Status: COMPLETED
Conditions: Hypertension
Interventions: BEHAVIORAL: Enhanced health education|BEHAVIORAL: Transcendental Meditation program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Photobiomodulation With REd vs BluE Light (REBEL)
Status: RECRUITING
Conditions: Dry Eye Syndromes|Meibomian Gland Dysfunction|Blepharitis
Interventions: DEVICE: Red LLLT|DEVICE: Blue LLLT|DEVICE: Sham Red LLLT|DEVICE: Sham Blue LLLT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prevent/Delay Development of Type 2 Diabetes in Subjects With Impaired Glucose Homeostasis Treated With Acarbose in Primary Care
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: DRUG: Acarbose (Glucobay, BAYG5421)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Heat Shock Protein-Peptide Complex (HSPPC-96) Versus IL-2/DTIC for Stage IV Melanoma
Status: COMPLETED
Conditions: Malignant Melanoma
Interventions: DRUG: HSPPC-96 or Oncophage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Same-Day Combination of VI Peel and Botox for Correction of Sun Damage, Fine Lines and Wrinkles
Status: COMPLETED
Conditions: Photoaging|Wrinkle|Sun Damaged Skin
Interventions: COMBINATION_PRODUCT: Same Day Intervention of VI Peel (Procedure) and Botulinum Toxin (Drug)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Internet Enhanced, Patient-Centered Orthopedic Care: A Prospective, Randomized, Controlled Pilot Trial
Status: COMPLETED
Conditions: Knee Injuries|Shoulder Injuries|Rotator Cuff Disease|Meniscus Tear|Patellofemoral Pain
Interventions: OTHER: eRehab|OTHER: Formal Physical Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assess Efficacy and Safety of Epeleuton in Patients With Hypertriglyceridemia and Type 2 Diabetes
Status: TERMINATED
Conditions: Hypertriglyceridemia|Type 2 Diabetes
Interventions: DRUG: DS102|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Trans Sodium Crocetinate (TSC) in Newly Diagnosed Glioblastoma (GBM) Biopsy-Only Subjects
Status: TERMINATED
Conditions: Glioblastoma
Interventions: DRUG: Trans Sodium Crocetinate plus SOC|OTHER: Standard of Care (SOC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HIT on Hypoglycemic Risk in Type 1 Diabetes (T1D)
Status: COMPLETED
Conditions: Type1diabetes
Interventions: BEHAVIORAL: high intensity interval training|BEHAVIORAL: moderate intensity continous training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: BE Study of the Combinations of Gemigliptin 50mg and Metformin HCl Extended Release 1000mg in Comparison to Each Component Administered Alone.
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: gemigliptin and metformin HCl extended release|DRUG: gemigliptin/metformin HCl sustained release
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Safety and Efficacy of MP-214 in Patients With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: MP-214 3mg|DRUG: MP-214 6mg|DRUG: MP-214 9mg|DRUG: Risperidone 4mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Palatal Wound Healing Evaluation After Application of Platelet Rich Fibrin Versus 0.2% Hyaluronic Acid Dressings
Status: COMPLETED
Conditions: Free Gingival Graft
Interventions: DRUG: hyaluronic acid (Gengiegel 0.2% oral gel )|OTHER: Platelet rich fibrin|OTHER: Gel foam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Preoperative TPF Chemotherapy in Molecularly Selected Locally Advanced Resectable Oral Cavity Squamous Cell Cancer
Status: COMPLETED
Conditions: Locally Advanced Resectable Oral Cavity Squamous Cell Cancer
Interventions: DRUG: docetaxel, cisplatin, 5 fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nutritional Counseling Associated With the Ingestion of Oat Bran in Hypercholesterolemic Subjects
Status: COMPLETED
Conditions: Dietary Modification
Interventions: DIETARY_SUPPLEMENT: oat bran - 40g|DIETARY_SUPPLEMENT: refined rice flour- 40g
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Temozolomide and Radiation Therapy With or Without Vatalanib in Treating Patients With Newly Diagnosed Glioblastoma Multiforme
Status: COMPLETED
Conditions: Brain and Central Nervous System Tumors
Interventions: DRUG: temozolomide|DRUG: vatalanib|PROCEDURE: adjuvant therapy|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rowing Biomechanics - Effects of (In)Stability and Fatigue
Status: COMPLETED
Conditions: Healthy
Interventions: DEVICE: Stable rowing simulator|DEVICE: Slides based rowing simulator|DEVICE: Tilt board based rowing simulator
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Testing of a New Therapeutic Vibration Device to Reduce Neuromuscular Weakness in Hospitalized Patients (Hospital Testing)
Status: WITHDRAWN
Conditions: Critically Ill
Interventions: DIAGNOSTIC_TEST: Therapeutic Vibration Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study to Investigate the Pharmacokinetics & Safety Following One Application of 3 Different Doses 0.5,0.75,& 1.25 gm,a Transdermal Estradiol Cream (VML-0203), in Comparison to a Single Dose of EstroGel 1.25 gm to Healthy Post-menopausal Women.
Status: UNKNOWN
Conditions: Menopause
Interventions: DRUG: Estrogel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy Study Image Guided, Auto-Targeted Neurostimulation for the Treatment of Non-Specific Low Back Pain
Status: COMPLETED
Conditions: Low Back Pain
Interventions: DEVICE: Image Guided TENS (Auto-Targeted Neurostimulation, NeMa-st)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Pulmonary Complications in Pediatric Patients With Storage Disorders Undergoing Allogeneic Hematopoietic Stem Cell Transplantation
Status: UNKNOWN
Conditions: I Cell Disease|Fucosidosis|Globoid Cell Leukodystrophy|Adrenoleukodystrophy|Mannosidosis|Niemann-Pick Disease|Pulmonary Complications|Mucopolysaccharidosis I|Mucopolysaccharidosis VI|Metachromatic Leukodystrophy|Gaucher's Disease|Wolman Disease
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pharmacokinetics of Adrenaline After Administration of ARS -1 in Subjects With Upper Respiratory Tract Infection
Status: COMPLETED
Conditions: Upper Respiratory Tract Infection
Interventions: DRUG: ARS-1 with URTI|DRUG: ARS-1 without URTI
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Web-based Approach in Nutrition and Diabetes
Status: UNKNOWN
Conditions: Type 2 Diabetes Mellitus|Overweight and Obesity|Nutritional and Metabolic Diseases
Interventions: OTHER: web-based thecnologies|BEHAVIORAL: traditional approach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to Assess the Safety and Pharmacokinetics of a Single Intravenous Administration of CNTO 328 Derived From 2 Different Cell Lines in Healthy Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: CNTO 328 (Sp2/0-derived)|DRUG: CNTO 328 (CHO-derived)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial to Test How Well Two Drugs, QAW039 and Montelukast Work Both Individually and Together, to Target Allergic Rhinitis Using an Environmental Exposure Chamber
Status: COMPLETED
Conditions: Allergic Rhinitis
Interventions: DRUG: QAW039|DRUG: Montelukast|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Impact of Grass SLIT Treatment on Birch Pollen Induced Allergic Rhinitis - a Pilot Evaluation
Status: COMPLETED
Conditions: Allergic Rhinoconjunctivitis
Interventions: DRUG: Grastek®|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: 5-Azacytidine and/or Nivolumab in Resectable HPV-Associated HNSCC
Status: RECRUITING
Conditions: Squamous Cell Carcinoma of Head and Neck
Interventions: DRUG: Combination 5-azacytidine and nivolumab|DRUG: 5-azacytidine|DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Prasugrel in Pediatric Participants With Sickle Cell Disease (SCD)
Status: TERMINATED
Conditions: Sickle Cell Disease
Interventions: DRUG: Prasugrel|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study on Screening, Verification and Intervention of High-risk Patients With Liver Cancer
Status: RECRUITING
Conditions: Hepatocellular Carcinoma|Chronic Hepatitis B
Interventions: DRUG: NAs（"Entecavir"or"Tenofovir"or"Tenofovir alafenamide"） combined with interferon treatments|DRUG: NAs （"Entecavir"or"Tenofovir"or"Tenofovir alafenamide"） treatments
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Interaction Between Ritonavir and Prasugrel in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Prasugrel|DRUG: Ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Vaccine Responsiveness After CAR-T Cell Therapy
Status: RECRUITING
Conditions: B-Cell Neoplasm
Interventions: BIOLOGICAL: Wistar Rabies Virus Strain PM-1503-3M Vaccine|PROCEDURE: Biospecimen Collection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Maximizing Treatment Outcome in Post-Traumatic Stress Disorder (PTSD)
Status: COMPLETED
Conditions: Post-Traumatic Stress Disorder
Interventions: BEHAVIORAL: Prolonged Exposure|BEHAVIORAL: Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vitamin D as a Factor Modifying Adaptation to Exercise
Status: COMPLETED
Conditions: Vitamin D3 Deficiency
Interventions: DIETARY_SUPPLEMENT: NW training|DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: HICT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Ticagrelor and Intracoronary Morphine in Patients Undergoing Primary Percutaneous Coronary Intervention
Status: UNKNOWN
Conditions: ST-Segment Elevation Myocardial Infarction
Interventions: DRUG: Ticagrelor|DRUG: Clopidogrel|DRUG: Morphine Sulfate|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Environmental Exposure to Lead and Progressive Renal Insufficiency in Type II Diabetic Nephropathy
Status: COMPLETED
Conditions: Diabetic Nephropathies|Diabetes Mellitus, Type II
Interventions: DRUG: EDTA chelating agents
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of 611 in Chinese Adults With Moderate to Severe Chronic Obstructive Pulmonary Disease
Status: RECRUITING
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: 611 300 mg Q2W|DRUG: 611 450 mg Q2W|DRUG: Matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 2a Study to Assess Safety & Pharmacokinetics of Sustained Release Sodium Nitrite in Patients With Diabetic Pain
Status: COMPLETED
Conditions: Diabetes
Interventions: DRUG: Sodium nitrite|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Erythrocyte Apheresis Versus Phlebotomy in Hemochromatosis
Status: UNKNOWN
Conditions: Hemochromatosis
Interventions: PROCEDURE: Arm 1: Erythrocyte apheresis|PROCEDURE: Arm 2: Whole blood phlebotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Peri-articular Injection and (IPACK) With Adductor Canal Block in Total Knee Arthroplasty.
Status: COMPLETED
Conditions: Postoperative Pain|Regional Anesthesia
Interventions: PROCEDURE: Adductor canal block (ACB) group|PROCEDURE: Peri-articular injection group|PROCEDURE: Adductor canal block and IPACK block group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Ganaxolone Treatment in Children With Fragile X Syndrome
Status: COMPLETED
Conditions: Fragile x Syndrome
Interventions: DRUG: Ganaxolone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Microfragmented Lipoaspirate Tissue in Arthroscopic Rotator Cuff Repair
Status: COMPLETED
Conditions: Rotator Cuff Tears
Interventions: PROCEDURE: arthroscopic rotator cuff repair|PROCEDURE: autologous micro-fragmented adipose tissue
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized, Multicenter Open Label Study Comparing Early Administration of Azathioprine Plus IFX to Steroids Plus Azathioprine for Acute Severe Colitis
Status: COMPLETED
Conditions: Ulcerative Colitis
Interventions: DRUG: Azathioprine|DRUG: Infliximab|DRUG: Prednisolone|DRUG: Hydrocortisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vitamin D to Improve Nutrition Prior to Bariatric Surgery and Investigate the Relationship With Negative Outcomes
Status: TERMINATED
Conditions: Vitamin D Deficiency|Vitamin D Insufficiency
Interventions: DIETARY_SUPPLEMENT: Vitamin D|OTHER: Placebo|OTHER: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacological Activation of HMN for OSA
Status: COMPLETED
Conditions: Obstructive Sleep Apnea
Interventions: DRUG: Placebo oral capsule|DRUG: LTM1201L|DRUG: LTM1201LN|DRUG: LTM1201LB|DRUG: LTM1201LD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Implementing PROMs and PREMs in Routine Clinical Care: Assessment of Requirements and Impact
Status: RECRUITING
Conditions: PROMs|PREMs|Implementation Research|Impact Evaluation
Interventions: OTHER: PROMs and PREMs|OTHER: PREMs|OTHER: Control|OTHER: Healthcare professionals
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study to Evaluate 608 in Patients With Ankylosing Spondylitis (AS)
Status: NOT_YET_RECRUITING
Conditions: Ankylosing Spondylitis
Interventions: DRUG: 608 Dose A|DRUG: 608 Dose B|DRUG: 608 Dose C|DRUG: Adalimumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: High Flow Nasal Oxygen at Extubation for Adults Requiring a Breathing Tube for Treating Severe Breathing Difficulties
Status: RECRUITING
Conditions: Respiratory Insufficiency
Interventions: DEVICE: Fisher and Paykel "HealthCare Airvo™ 3" high flow system|DEVICE: Conventional Oxygen Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Randomized Controlled Trial of Sertraline in Paroxysmal Arterial Hypertension
Status: UNKNOWN
Conditions: Hypertension
Interventions: DRUG: Sertraline|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Extended Follow-up of Treatment of Prednisone Plus Cyclophosphamide in Patients With Advanced-stage IgA Nephropathy
Status: UNKNOWN
Conditions: IgA Nephropathy
Interventions: DRUG: prednisone and cyclophosphamide|DRUG: prednisone alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Concurrent FOLFIRINOX Plus High Intensity Focused Ultrasound for Pancreatic Cancer
Status: RECRUITING
Conditions: Pancreatic Cancer Non-resectable|Chemotherapy Effect|Ultrasound Therapy
Interventions: DEVICE: ALPIUS 900, an ultrasound-guided high intensity focused ultrasound system|DRUG: FOLFIRINOX regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: VerifyNow to Optimise Platelet Inhibition in Coronary Acute Syndrome
Status: RECRUITING
Conditions: Acute Coronary Syndrome|Acute Myocardial Infarction|Coronary Artery Disease|Percutaneous Coronary Intervention
Interventions: DRUG: Clopidogrel|DRUG: Previous treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Observation of Ketamine Treatment Safety and Tolerability in Adult Psychiatry Clinic Medical University of Gdańsk Inpatients
Status: ENROLLING_BY_INVITATION
Conditions: Major Depressive Disorder|Post Traumatic Stress Disorder|Obsessive-Compulsive Disorder|Somatoform Disorders|Anxiety Disorders|Dissociative Disorder
Interventions: DRUG: Ketamine Hydrochloride
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of a Combined Drainage Strategy in Uniportal Upper Lung Lobectomy
Status: UNKNOWN
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: PROCEDURE: prophylactic air-extraction catheter drainage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Dendritic Cell Vaccine for High Risk Ovarian Cancer Patients
Status: COMPLETED
Conditions: Ovarian Cancer|Fallopian Tube Cancer|Primary Peritoneal Carcinoma
Interventions: BIOLOGICAL: DC-Ova|BIOLOGICAL: DC Ova with Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Walnut Oral Immunotherapy for Tree Nut Allergy
Status: WITHDRAWN
Conditions: Nut Hypersensitivities
Interventions: DRUG: Walnut Protein Flour|DRUG: Oat flour
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Single Versus Double Drains After Mastectomy
Status: COMPLETED
Conditions: Breast Cancer|Mastectomy
Interventions: PROCEDURE: Insertion of a single drain|PROCEDURE: Insertion of double drains|PROCEDURE: Ultrasonography after removal of the drains
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Device Assisted Full Thickness Resection Versus Endoscopic Submucosal Dissection for Duodenal Neuroendocrine Tumors
Status: RECRUITING
Conditions: Neuroendocrine Tumors
Interventions: PROCEDURE: Endoscopic submucosal dissection|DEVICE: EFTR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized Controlled Trial of Patient-Centered Self-Management Intervention in Adults With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: BEHAVIORAL: PAtient CEntered Self-Management Intervention (PACE-SMI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Coaching Patients on Pain Control With and Without Financial Incentivization
Status: WITHDRAWN
Conditions: Opioid Use
Interventions: OTHER: Possible Incentive for Tablet Return|OTHER: Incentive for Completed Diary|BEHAVIORAL: Coaching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: DNA Analysis of Bone Marrow and Blood Samples From Young Patients With Acute Myeloid Leukemia or Acute Lymphoblastic Leukemia
Status: COMPLETED
Conditions: Leukemia
Interventions: GENETIC: Southern blotting|GENETIC: chromosomal translocation analysis|GENETIC: cytogenetic analysis|GENETIC: gene rearrangement analysis|GENETIC: mutation analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Cabozantinib With Topotecan-Cyclophosphamide
Status: COMPLETED
Conditions: Relapsed Ewing Sarcoma|Refractory Ewing Sarcoma|Relapsed Osteosarcoma|Refractory Osteosarcoma
Interventions: DRUG: Cabozantinib|DRUG: Topotecan|DRUG: Cyclophosphamide|DRUG: Myeloid growth factor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ulipristal Acetate for Use in Early Pregnancy Loss
Status: COMPLETED
Conditions: Missed Abortion|Anembryonic Pregnancy|Non-Viable Pregnancy
Interventions: DRUG: Ulipristal Acetate Tablets|DRUG: Misoprostol Pill
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Comparing Weekly Taxol and Carboplatin vs Standard Taxol and Carboplatin Regimen for Stage IIIB or IV Non-Small-Cell Lung Cancer
Status: COMPLETED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: Paclitaxel and carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Extension Study of Protocol ENB-002-08 - Study of Asfotase Alfa in Infants and Young Children With Hypophosphatasia (HPP)
Status: COMPLETED
Conditions: Hypophosphatasia
Interventions: BIOLOGICAL: asfotase alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Nivolumab Combination Treatment in Resectable Non-small Cell Lung Cancer Patients
Status: RECRUITING
Conditions: NSCLC Stage II|NSCLC, Stage IIIA|NSCLC, Stage I
Interventions: DRUG: Nivolumab 10 MG/ML Intravenous Solution|DRUG: Relatlimab 10 MG/ML Intravenous Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT