pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Effect of COX-2 and EGFR Suppression on Molecular Markers of Angiogenesis and Proliferation in Squamous Cell Carcinoma of Oral Cavity - Prospective Randomized Study
Status: UNKNOWN
Conditions: Oral Squamous Cell Carcinoma|Carcinoma of Buccal Mucosa|Tongue Cancers|Head and Neck Cancers
Interventions: DRUG: Arm1|DRUG: Arm 2|DRUG: Arm 3|OTHER: Arm 4
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study To Compare Single Dose Of Three Modified Release Formulations Of PF-04937319 With Immediate Release Material-Sparing-Tablet (IR MST) Formulation Previously Studied In Adults With Type 2 Diabetes Mellitus.
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: PF-04937319 IR MST|DRUG: PF-04937319 MR 1|DRUG: PF-04937319 MR 2|DRUG: PF-04937319 MR 3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Phase I Study of Q702 With Azacitidine and Venetoclax for Relapsed or Refractory Acute Myeloid Leukemia
Status: NOT_YET_RECRUITING
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Azacitidine|DRUG: Venetoclax|DRUG: Q702
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Study To Estimate The Relative Bioavailability Of Fixed Combination Tablets Of Azithromycin And Chloroquine Compared To Co-Administered Individual Tablets Of Azithromycin And Chloroquine
Status: COMPLETED
Conditions: Malaria
Interventions: DRUG: Fixed combination of Azithromycin and Chloroquine|DRUG: Azithromycin and Chloroquine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Adjuvant Treatment in Extensive Unilateral Retinoblastoma Primary Enucleated (RB SFCE 2009)
Status: RECRUITING
Conditions: Retinoblastoma
Interventions: OTHER: Observation|DRUG: Etoposide|DRUG: Vincristine|RADIATION: Orbital irradiation|DRUG: Carboplatin|DRUG: Vincristine|DRUG: Cyclophosphamide|DRUG: Carboplatin|DRUG: Etoposide|DRUG: Carboplatin|DRUG: Thiotepa|DRUG: Vincristine|DRUG: Cyclophosphamide|PROCEDURE: Cytapheresis|DRUG: Carboplatin|DRUG: Etoposide|DRUG: Thiotepa|PROCEDURE: Peripheral bood stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mannitol - Potential Role in Hemodialysis Initiation for Reduction of Intra-dialytic Hypotension
Status: COMPLETED
Conditions: Intra-dialytic Hypotension
Interventions: DRUG: Mannitol (20%)|DRUG: 0.9% saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Blood Pressure Lowering in Dialysis (BOLD) Trial
Status: COMPLETED
Conditions: Blood Pressure|End Stage Renal Disease on Dialysis (Diagnosis)|Chronic Kidney Diseases|Chronic Kidney Disease Stage 5
Interventions: DRUG: Anti-Hypertensive medications|PROCEDURE: Dry Weight Adjustment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improving Informed Consent for Cleft Palate Repair
Status: UNKNOWN
Conditions: Cleft Palate|Jaw Abnormalities|Maxillofacial Abnormalities|Mouth Abnormalities|Congenital Abnormalities|Jaw Diseases|Musculoskeletal Diseases|Craniofacial Abnormalities|Musculoskeletal Abnormalities|Stomatognathic Diseases|Stomatognathic System Abnormalities
Interventions: BEHAVIORAL: Pamphlet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Mulligan Mobilization With Movement Versus Macquarie Injury Management Group in Function and Pain of Knee Osteoarthritis
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: OTHER: Macquarie Injury Management group|OTHER: Mulligan Mobilization with Movement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Long-term Safety and Performance of KiOmedine CM-Chitosan Supplementation in Advanced Symptomatic Knee Osteoarthritis
Status: ACTIVE_NOT_RECRUITING
Conditions: Osteoarthritis, Knee
Interventions: DEVICE: KiOmedine® CM-Chitosan|DEVICE: Synvisc-One®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: MK-0431 Early Phase II Double-blind Study - Type 2 Diabetes Mellitus (0431-043)
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: MK0431, sitagliptin phosphate / Duration of Treatment: 12 Weeks|DRUG: Comparator : placebo (unspecified) / Duration of Treatment: 12 Weeks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Informed Consent Formats by Information Preference and Priority
Status: COMPLETED
Conditions: Consent Forms|Asthma
Interventions: BEHAVIORAL: Original consent form|BEHAVIORAL: Shortened consent form|BEHAVIORAL: Reordered, shortened consent form|BEHAVIORAL: Shortened consent form with a highlights box|BEHAVIORAL: Interactive, shortened consent form
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Humalog® Mix50/50(tm) as a Treatment for Gestational Diabetes
Status: COMPLETED
Conditions: Gestational Diabetes Mellitus
Interventions: DRUG: Insulin LISPRO|DRUG: Insulin, Long-Acting and Insulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Tivozanib (AV-951), an Oral VEGF Receptor Tyrosine Kinase Inhibitor, in the Treatment of Renal Cell Carcinoma
Status: COMPLETED
Conditions: Carcinoma, Renal Cell
Interventions: DRUG: Tivozanib (AV-951)|DRUG: Placebo comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate ALN-AGT01 in Patients With Hypertension
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: ALN-AGT01|DRUG: ALN-AGT01-Matching Placebo|DRUG: Irbesartan|DRUG: Irbesartan-Matching Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial to Evaluate the Safety of Talimogene Laherparepvec Injected Into Tumors Alone and in Combination With Systemic Pembrolizumab MK-3475-611/Keynote-611
Status: COMPLETED
Conditions: Hepatocellular Carcinoma|Liver Metastases|Cutaneous or Subcutaneous Lymph Node|Liver Tumors
Interventions: DRUG: Talimogene Laherparepvec|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Erlotinib Plus Radiotherapy (RT) for Patients With Advanced or Inoperable Non-Small-Cell Lung Cancer
Status: COMPLETED
Conditions: Carcinoma, Non-small-cell Lung
Interventions: DRUG: Erlotinib|RADIATION: Hypofractionated Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nasonex Compared With Placebo in Participants With Seasonal Allergic Rhinitis (SAR) and Concomitant Asthma (P03280)
Status: COMPLETED
Conditions: Rhinitis, Allergic, Seasonal|Asthma
Interventions: DRUG: Mometasone|DRUG: Placebo|DRUG: Albuterol/Salbutamol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Human Upper Extremity Allotransplantation
Status: RECRUITING
Conditions: Amputation, Traumatic|Wounds and Injuries|Hand Injuries
Interventions: PROCEDURE: Deceased donor hand transplantation|DRUG: Bone marrow cell-based therapy & single-drug immunosuppression.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anti-HIV Drug Regimens With or Without Protease Inhibitors and Drug Level Monitoring in HIV Infected Adolescents
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Efavirenz + 2 NRTIs|DRUG: Lopinavir/Ritonavir + 2 NRTIs|PROCEDURE: Therapeutic Drug Monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Collection and Distribution of Biospecimens for Novel Research
Status: ENROLLING_BY_INVITATION
Conditions: Cancer|Healthy|Gastrointestinal Complication|Autoimmune Diseases|Infectious Disease|Women's Health: High-Risk Pregnancy|Dermatologic Disease|Blood Disease
Interventions: OTHER: Observational
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Semi-replicate Crossover Bioequivalence Study of Dirithromycin in Healthy Subjects Under Fed Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: DIRITHROMYCIN 500 MG ENTERIC COATED TABLET|DRUG: DYNABAC 250 MG ENTERIC COATED TABLET
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Blueberry Consumption on Metabolic Syndrome & DNA Damage
Status: COMPLETED
Conditions: Metabolic Syndrome|Insulin Resistance|DNA Damage
Interventions: DIETARY_SUPPLEMENT: Blueberry Powder|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: STRESS From in Charge Relative Facing the Announcement of Decisions Limiting or Stopping Treatments in Emergency Room During the COVID-19 Epidemic
Status: UNKNOWN
Conditions: Covid19|Post Traumatic Stress Disorder|Anxiety
Interventions: OTHER: Post traumatic, Anxiety and depression evaluation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Traumatic Brain Injury and the Gut Microbiome
Status: COMPLETED
Conditions: Brain Injury, Chronic|Brain Injuries, Traumatic
Interventions: DIETARY_SUPPLEMENT: Inulin fructooligosaccharide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Taxotere, Cisplatin, and CPT-11 in Advanced Solid Tumor Malignancies
Status: COMPLETED
Conditions: Solid Tumor
Interventions: DRUG: Taxotere|DRUG: Cisplatin|DRUG: CPT-11
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study of IgAN, LN, MN, & C3 Glomerulopathy Including Dense Deposit Disease Treated With OMS721
Status: UNKNOWN
Conditions: IgAN|Lupus Nephritis|MN|C3 Glomerulopathy
Interventions: BIOLOGICAL: OMS721 (narsoplimab)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Interaction Between ASP1707 and Itraconazole in Healthy Female Subjects
Status: COMPLETED
Conditions: Pharmacokinetics|DDI (Drug-Drug Interaction)|Healthy Subjects
Interventions: DRUG: ASP1707|DRUG: itraconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: 10-day Decitabine, Fludarabine and 2 Gray TBI as Conditioning Strategy for Poor and Very Poor Risk AML in CR1
Status: COMPLETED
Conditions: Acute Myeloid Leukemia (AML)
Interventions: DRUG: decitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Interleukin-7 and Chemokine (C-C Motif) Ligand 19-expressing CD19-CAR-T for Refractory/Relapsed B Cell Lymphoma.
Status: UNKNOWN
Conditions: B Cell Lymphoma
Interventions: BIOLOGICAL: Interleukin-7 and Chemokine (C-C Motif) Ligand 19-expressing CD19-CAR-T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Safety, Tolerability, and Hemodynamic Response of PB1046 in Subjects With PAH
Status: COMPLETED
Conditions: Pulmonary Arterial Hypertension
Interventions: DRUG: PB1046 Subcutaneous Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Durvalumab and Tremelimumab After Radiation for Microsatellite Stable Metastatic Colorectal Cancer Progressing on Chemotherapy
Status: COMPLETED
Conditions: Colorectal Cancer Metastatic
Interventions: DRUG: durvalumab|DRUG: Tremelimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preoperative vs Postoperative Hypofractionated Radiosurgery for Patients With Large Brain Metastases
Status: RECRUITING
Conditions: Brain Metastases, Adult
Interventions: RADIATION: Hypofractionated Radiosurgery (HSRS)|PROCEDURE: Brain metastases surgical resection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stem Cell Transplant to Treat Patients With Favorable or Intermediate Risk Minimal Residual Disease Negative Acute Myeloid Leukemia
Status: WITHDRAWN
Conditions: Acute Myeloid Leukemia|Minimal Residual Disease Negativity
Interventions: PROCEDURE: Autologous Hematopoietic Stem Cell Transplantation|DRUG: Busulfan|DRUG: Etoposide|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fetal Distribution of Feto-placental Blood Flow Related to Placental Nutrient Transport and Maternal Food Intake
Status: UNKNOWN
Conditions: Fetal Growth Restriction
Interventions: OTHER: Standard breakfast meal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Multicenter Prospective Randomized Controlled Study of RPD Versus LPD
Status: NOT_YET_RECRUITING
Conditions: Pancreatic Cancer|Common Bile Duct Diseases|Periampullary Carcinoma
Interventions: PROCEDURE: laparoscopic pancreaticoduodenectomy|PROCEDURE: Robot Pancreaticoduodenectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact Of Mindfulness Breathing Versus Storytelling On Non- Specific Insomnia In Elderly
Status: RECRUITING
Conditions: Insomnia|Sleep Disorder
Interventions: OTHER: storytelling|OTHER: Mindfulness breathing|OTHER: Sleep hygiene
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Bioequivalence Study of Fixed-dose Combination of Vildagliptin and Metformin HCI 50/1000 mg FCT Under Fed Conditions
Status: NOT_YET_RECRUITING
Conditions: Healthy Volunteer
Interventions: DRUG: Vildagliptin and Metformin Hydrochloride 50mg 1000 mg Film-coated Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: IReversible Electroporation of Kidney Tumors Before Partial Nephrectomy.
Status: UNKNOWN
Conditions: Kidney Tumor|Renal Cell Cancer
Interventions: PROCEDURE: Irreversible Electroporation (IRE)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lymphatic Phenotype in Noonan Syndrome Spectrum Disorders
Status: RECRUITING
Conditions: Lymphatic System Disorders Congenital|Lymphatic Diseases|Noonan Syndrome|Lymphatic Disease
Interventions: DIAGNOSTIC_TEST: Dynamic contrast-enhanced lymphangiography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy and Safety of Lacidipine in Chronic Stable Angina
Status: COMPLETED
Conditions: Angina Pectoris
Interventions: DRUG: Lacidipine, low dose|DRUG: Lacidipine, medium dose|DRUG: Lacidipine, high dose|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Acute Biliary Pancreatitis - Optimal Time for Cholecystectomy
Status: COMPLETED
Conditions: Acute Biliary Pancreatitis
Interventions: PROCEDURE: early cholecystectomy|PROCEDURE: delayed cholecystectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Lactoferrin Prophylaxis in VLBW and Regulator T-cells
Status: COMPLETED
Conditions: Late Onset Neonatal Sepsis|Necrotising Enterocolitis|Very Low Birth Weight Infants
Interventions: DIETARY_SUPPLEMENT: Lactoferrin (bovine origin)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Metabolomic Signature of Exogenous Ketosis
Status: COMPLETED
Conditions: Ketosis
Interventions: DIETARY_SUPPLEMENT: (R)-3-hydroxybutyl (R)-3-hydroxybutyrate ketone monoester
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Fluoroless-CSP Trial Using Electroanatomic Mapping
Status: ENROLLING_BY_INVITATION
Conditions: Sinus Node Dysfunction|Heart Block AV|LBBB|Heart Failure, Systolic
Interventions: PROCEDURE: Conventional fluoroscopy guided Conduction System Pacing(CSP)|PROCEDURE: Electroanatomic Mapping (Fluoroless) guided Conduction System Pacing(CSP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Hypoallergenicity Evaluation of a New Extensively Hydrolyzed Formula
Status: COMPLETED
Conditions: Cow Milk Allergy
Interventions: OTHER: Test extensively hydrolyzed formula|OTHER: Control extensively hydrolyzed formula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prevention of Vaso-occlusive Painful Crisis by Using Omega-3 Fatty Acid Supplements
Status: UNKNOWN
Conditions: Sickle Cell Disease
Interventions: DIETARY_SUPPLEMENT: Omega-3 capsules|DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: Omega-3 capsules|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Enzalutamide & Dutasteride/Finasteride as 1st Line Treatment for Patients =/> 65 Years Old With Prostate Cancer.
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: Enzalutamide and Dutasteride or finasteride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Characterization of Different Phenotypes of Microvascular Dysfunction and Their Impact on Angina Severity in Patients With Chronic Angina in the Absence of Obstructive Coronary Artery Disease.
Status: RECRUITING
Conditions: Angina CCS Classe II-IV - IMR, RFR, FFR,CFR
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pembrolizumab in Combination With CRT for LA-SCCHN
Status: ACTIVE_NOT_RECRUITING
Conditions: Head and Neck Cancer|Squamous Cell Carcinoma|Oral Cavity Cancer|Oropharynx Cancer|Hypopharynx Cancer|Larynx Cancer|Laryngeal Cancer
Interventions: DRUG: pembrolizumab (MK-3475)|DRUG: Cisplatin|RADIATION: Radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of OSE-127 vs Placebo in Patients With Moderate to Severe Active Ulcerative Colitis
Status: UNKNOWN
Conditions: Ulcerative Colitis
Interventions: DRUG: OSE-127|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Intrapulmonary Pharmacokinetics of SPR859 by Comparing the Plasma, Epithelial Lining Fluid (ELF), and Alveolar Macrophages (AM) Concentrations Following the Oral Administration of Five Doses of SPR994 in Healthy, Nonsmoking Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: TBPM-PI-HBr
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Young and Strong: An Education and Supportive Care Intervention Study for Young Women With Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: BEHAVIORAL: Young Women's Intervention (YWI)|BEHAVIORAL: Physical Activity Intervention (PAI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Livionex Oral Microbiome and Dental Plaque Control in HSCT Recipients
Status: RECRUITING
Conditions: Dental Plaque
Interventions: DRUG: Livionex® Dental Gel|DRUG: PreviDent 5000 plus/Tom's of Maine Children's toothpaste|DEVICE: Kolibree Toothbrush
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Adjunctive Low-dose Metformin in Patients With Schizophrenia and Metabolic Abnormalities
Status: COMPLETED
Conditions: Metabolic Syndrome
Interventions: DRUG: metformin 500 mg|DRUG: clozapine 100 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: BabyStrong Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) Paired Bottle Feeding to Improve Oral Feeding
Status: RECRUITING
Conditions: Infant Feeding Problems, taVNS
Interventions: DEVICE: transcutaneous auricular vagus nerve stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Hysteroscopic Method With Vaporization in the Hysteroscopic Treatment of Submucosal Uterine Fibroids
Status: RECRUITING
Conditions: Uterine Fibroids
Interventions: PROCEDURE: OHR VS OHV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anti-Angiogenesis Therapy Using Thalidomide in Patients With Waldenstrom's Macroglobulinemia
Status: COMPLETED
Conditions: Waldenstrom Macroglobulinemia
Interventions: DRUG: Thalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Impact of the MUSE Meditation Device on Student Registered Nurse Anesthetists
Status: COMPLETED
Conditions: Stress|Anxiety|Affect|Burnout, Professional
Interventions: DEVICE: MUSE Meditation Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy and Safety Study of Botulinum Toxin Type A Against Placebo to Treat Spasticity in the Leg After a Stroke
Status: COMPLETED
Conditions: Post-stroke Spasticity of the Lower Limb
Interventions: DRUG: IncobotulinumtoxinA (400 Units)|DRUG: Placebo Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Organic Pollutants in Pelvic Endometriosis
Status: COMPLETED
Conditions: Endometriosis|Infertility Unexplained
Interventions: DIAGNOSTIC_TEST: Detection of PAHs in visceral fat with gas chromatography-isotope dilution mass spectrometry
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Stretching Exercises on Hamstring Flexibility.
Status: COMPLETED
Conditions: Hamstring Muscle|Flexibility
Interventions: OTHER: sub-occipital muscle inhibition technique|OTHER: Neurodynamic mobilization|OTHER: control (passive stretch exercises)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pulmonary Physiologic Assessment of Patients on Veno-arterial Extracorporeal Membrane Oxygenation (VA ECMO)
Status: WITHDRAWN
Conditions: Cardiac Arrest|Pulmonary Injury
Interventions: PROCEDURE: Veno-arterial extracorporeal membrane oxygenation (VA-ECMO)|DEVICE: Electrical Impedance Tomography (EIT)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Etanercept in Treating Young Patients With Idiopathic Pneumonia Syndrome After Undergoing a Donor Stem Cell Transplant
Status: COMPLETED
Conditions: Accelerated Phase Chronic Myelogenous Leukemia|Blastic Phase Chronic Myelogenous Leukemia|Childhood Acute Lymphoblastic Leukemia in Remission|Childhood Acute Myeloid Leukemia in Remission|Childhood Chronic Myelogenous Leukemia|Childhood Myelodysplastic Syndromes|Chronic Phase Chronic Myelogenous Leukemia|de Novo Myelodysplastic Syndromes|Disseminated Neuroblastoma|Juvenile Myelomonocytic Leukemia|Previously Treated Childhood Rhabdomyosarcoma|Previously Treated Myelodysplastic Syndromes|Pulmonary Complications|Recurrent Childhood Acute Lymphoblastic Leukemia|Recurrent Childhood Acute Myeloid Leukemia|Recurrent Childhood Large Cell Lymphoma|Recurrent Childhood Lymphoblastic Lymphoma|Recurrent Childhood Rhabdomyosarcoma|Recurrent Childhood Small Noncleaved Cell Lymphoma|Recurrent Neuroblastoma|Recurrent Wilms Tumor and Other Childhood Kidney Tumors|Recurrent/Refractory Childhood Hodgkin Lymphoma|Relapsing Chronic Myelogenous Leukemia|Secondary Acute Myeloid Leukemia|Secondary Myelodysplastic Syndromes
Interventions: BIOLOGICAL: etanercept|DRUG: methylprednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low-Level Laser Therapy and Flapless Corticopuncture Effect on Accelerating Six Maxillary Anterior Teeth Retraction
Status: COMPLETED
Conditions: Malocclusion, Angle Class II, Division 1
Interventions: RADIATION: Low-Level Laser Therapy (LLLT)|PROCEDURE: Flapless Corticopunture|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: LIFEwithIBD: Living With Intention, Fullness and Engagement With Inflammatory Bowel Disease
Status: COMPLETED
Conditions: Inflammatory Bowel Diseases
Interventions: BEHAVIORAL: LIFEwithIBD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pulmonary Vein Diameter and Collapsibility Measured by TEE to Predict Elevated Left Atrial Pressure in Cardiac Surgery
Status: COMPLETED
Conditions: Elevated Left Atrial Pressure
Interventions: OTHER: Standard TEE exam including measurement of left upper pulmonary vein diameter and collapsibility, compared with PCWP measured continuously by a pulmonary arterial catheter
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: APPETITE: Plant Protein and Exercise Solutions for the Prevention of Undernutrition in Older Adults.
Status: RECRUITING
Conditions: Appetite Loss|Physical Inactivity|Undernutrition|Anorexia of Aging|Aging|Ageing Well
Interventions: BEHAVIORAL: Physical activity intervention|DIETARY_SUPPLEMENT: Personalised nutrition intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: IN.PACT™ Quality of Life Post-Reimbursement Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Obstructive Disease|Atherosclerosis of Femoral Artery|Atherosclerosis of Popliteal Artery
Interventions: COMBINATION_PRODUCT: IN.PACT™ Admiral™ Drug Coated Balloon (DCB)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Laparoscopic IPOM Plus vs. eTEP Trial
Status: RECRUITING
Conditions: Incisional Hernia of Midline of Abdomen
Interventions: PROCEDURE: Lap IPOM plus|PROCEDURE: eTEP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of a Frequency-tuned Electromagnetic Field Treatment in Facilitating the Recovery of Subacute Ischemic Stroke Patients - a Pivotal Study (THE "EMAGINE" STUDY)
Status: COMPLETED
Conditions: Ischemic Stroke
Interventions: DEVICE: BQ 2.0|DEVICE: BQ 2.0
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Ischemic Preconditioning and Thiol-disulfide Balance
Status: COMPLETED
Conditions: Tourniquets
Interventions: OTHER: Remote Ischemic Preconditioning|OTHER: sham group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Levetiracetam in Control of Neonatal Seizures Guided by an EEG
Status: UNKNOWN
Conditions: Neonatal Seizures
Interventions: DRUG: Levetiracetam|DRUG: Phenobarbital
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Norursodeoxycholic Acid in the Treatment of Primary Sclerosing Cholangitis
Status: COMPLETED
Conditions: Primary Sclerosing Cholangitis
Interventions: DRUG: norUDCA|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial of a Hemp-Derived, High Cannabidiol Product for Anxiety in Glioblastoma Patients
Status: RECRUITING
Conditions: Glioblastoma
Interventions: DRUG: Cannabidiol (CBD)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cryoablation of the Retrograde Fast Pathway as Treatment for AVNRT
Status: UNKNOWN
Conditions: Atrioventricular Node Arrhythmia
Interventions: PROCEDURE: Cardiac catheter ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intradermal Vaccination With Stabilized Tumor mRNA - a Clinical Phase I/II Trial in Melanoma Patients
Status: COMPLETED
Conditions: Malignant Melanoma
Interventions: BIOLOGICAL: mRNA|DRUG: GM-CSF s.c.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Novel Method of Lung Isolation Compared With Standard Methods in a Model of Massive Pulmonary Hemorrhage
Status: UNKNOWN
Conditions: Pulmonary Hemorrhage
Interventions: DEVICE: Bronchial Blocker
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Can Flaxseed Prevent Broken Hearts in Women With Breast Cancer Study?
Status: UNKNOWN
Conditions: Cardiotoxicity
Interventions: DIETARY_SUPPLEMENT: Flax "milk"|DIETARY_SUPPLEMENT: Oat fibre "milk"
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Treatment Study in Patients Treated With Both Insulin & Hydrocortisone
Status: NOT_YET_RECRUITING
Conditions: Diabetes Mellitus|Adrenal Insufficiency|Polyglandular Autoimmune Syndrome
Interventions: DRUG: OD dual-release Hydrocortisone|DRUG: TID Hydrocortisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multimedia Self-Management Intervention for Lung Cancer Surgery Family Caregivers and Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Caregiver|Stage I Lung Cancer AJCC v7|Stage IA Lung Cancer AJCC v7|Stage IB Lung Cancer AJCC v7|Stage II Lung Cancer AJCC v7|Stage IIA Lung Cancer AJCC v7|Stage IIB Lung Cancer AJCC v7|Stage III Lung Cancer AJCC v7|Stage IIIA Lung Cancer AJCC v7|Stage IIIB Lung Cancer AJCC v7
Interventions: OTHER: Informational Intervention|OTHER: Informational Intervention|OTHER: Informational Intervention|OTHER: Informational Intervention|OTHER: Media Intervention|OTHER: Media Intervention|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Nicotine Pharmacokinetic Profile and Safety of the Tobacco Heating System 2.2 (THS 2.2)
Status: COMPLETED
Conditions: Smoking
Interventions: OTHER: THS 2.2|OTHER: CC|OTHER: NRT Gum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Effect of High and Low Sodium Intake on Urinary Aquaporin-2 in Autosomal Dominant Polycystic Kidney Disease
Status: COMPLETED
Conditions: Polycystic Kidney, Autosomal Dominant
Interventions: BEHAVIORAL: High Sodium Diet|BEHAVIORAL: Low Sodium Diet|BEHAVIORAL: Hypertonic saline infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Precision Medicine for Patients With Identified Actionable Mutations
Status: TERMINATED
Conditions: Solid Tumor|Lymphoma|Multiple Myeloma|Malignant Neoplasm|Mutation Abnormality
Interventions: DRUG: Investigational Agent|OTHER: Supportive Care Regimens|DIAGNOSTIC_TEST: Next Gen Sequencing Report
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reconstruction Following Pancreaticoduodenectomy: A Randomized Clinical Trial of Pancreaticojejunostomy vs Pancreaticogastomy
Status: COMPLETED
Conditions: Pancreas Cancer|Periampullary Cancer
Interventions: PROCEDURE: pancreaticojejunostomy vs pancreaticogastrostomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cobra II Study: Use of the Cobra™ Cobalt Super Alloy Coronary Stent System in the Treatment of Coronary Artery Disease
Status: UNKNOWN
Conditions: Coronary Artery Disease
Interventions: DEVICE: PCI with the Cobra™ Cobalt Super Alloy Coronary Stent System
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Aquatic High Intensity Resistive Training on Patients With Chronic Heart Failure
Status: RECRUITING
Conditions: Heart Failure
Interventions: OTHER: aquatic high intensity resistive training|OTHER: usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of BIA 5-1058 400 mg on the Steady State Pharmacokinetics of Bosentan
Status: COMPLETED
Conditions: Pulmonary Arterial Hypertension
Interventions: DRUG: BIA 5-1058|DRUG: bosentan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bevacizumab With or Without Thalidomide in Treating Patients With Relapsed or Refractory Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma and Plasma Cell Neoplasm
Interventions: BIOLOGICAL: bevacizumab|DRUG: thalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Study of CNTO 3157 in Healthy Volunteers and Patients With Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: BIOLOGICAL: CNTO 3157 or placebo|BIOLOGICAL: CNTO 3157 or placebo|BIOLOGICAL: CNTO 3157 or placebo|BIOLOGICAL: CNTO 3157 or placebo|BIOLOGICAL: CNTO 3157 or placebo|BIOLOGICAL: CNTO 3157 or placebo|BIOLOGICAL: CNTO 3157 or placebo|BIOLOGICAL: CNTO 3157 or placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of an Active Lifestyle Promotion Program for Patients With Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: OTHER: Physical therapy aimed to move safely|OTHER: Physical Therapy aimed to improve Physical Activity
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Alpha-Ketoglutarate and Abdominal Aortic Aneurysm Progression and Rupture
Status: RECRUITING
Conditions: Patients With an Abdominal Aortic Aneurysm of 39-49 mm in Diameter
Interventions: DIETARY_SUPPLEMENT: alpha-ketoglutarate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Incorporation of Muscle Qualities in Biomechanical Models of the Upper Limbs
Status: WITHDRAWN
Conditions: Shoulder Prosthesis
Interventions: PROCEDURE: Simultaneous controlled power measurement|PROCEDURE: Surface EMG measurement
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Phase 1 Study of Alisertib Participants With Advanced Solid Tumors Including Castration-Resistant Prostate Cancer Receiving a Standard Docetaxel Regimen
Status: COMPLETED
Conditions: Advanced Solid Tumors|Adenocarcinoma of the Prostate
Interventions: DRUG: Alisertib|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Efficacy and Safety When Administered JP-2266 in Type 2 Diabetes Patients
Status: NOT_YET_RECRUITING
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: SGLT2 inhibitor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: : "Comparative Evaluation of 3 Dimensional Changes of Dentition in Post Orthodontic Patients With Immediate vs Delayed (Post 3 Days) Retainer Delivery
Status: RECRUITING
Conditions: Relapse
Interventions: OTHER: immediate orthodontic retainer delivery|OTHER: delayed orthodontic retainer delivery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Montelukast for Treatment of Uremic Pruritus
Status: COMPLETED
Conditions: Renal Insufficiency, Chronic
Interventions: DRUG: Montelukast|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Cost-effectiveness of Hysterosalpingography Versus Hysterosalpingo-foam Sonography During Fertility Work-up
Status: RECRUITING
Conditions: Infertility
Interventions: PROCEDURE: Oil-based contrast|PROCEDURE: ExEm Foam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Interactive Sections Of An Internet-Based Intervention Increase Patient Empowerment: A Study With Chronic Back Pain Patients
Status: COMPLETED
Conditions: Group 1 (Control): Access to a Static Version of the Website Containing Only Static Features (i.e. Library, First Aid, and FAQ)|Group2 (Intervention) Access to an Interactive Version of the Website Containing Both Static and Interactive Features
Interventions: OTHER: Internet-based
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study in Healthy Men to Test How Different Doses of BI 3000202 Are Tolerated and How Food Influences the Amount of BI 3000202 in the Blood
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BI 3000202|DRUG: Placebo matching BI 3000202
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Holmium Laser Uretherotomy in Combination With Intralesional Steroids in Bulbar Uretheral Stricture
Status: COMPLETED
Conditions: Urethral Stricture
Interventions: PROCEDURE: Laser uretherotomy|PROCEDURE: Laser uretherotomy with triamcinolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Safety, Tolerability, Pharmacokinetics and Pharmacodynamics Study of the Topical Formulation SB011 Applied to Lesional Skin in Patients With Atopic Eczema
Status: COMPLETED
Conditions: Mild to Moderate Atopic Dermatitis
Interventions: DRUG: SB011, 2 % (Water/Oil/Water) emulsion of hgd40|DRUG: Multiple W/O/W formulation, active ingredient-free vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ultrasound Guidance for Radial Arterial Blood Sampling
Status: COMPLETED
Conditions: Radial Artery|Ultrasonography
Interventions: PROCEDURE: Artery puncture with ultrasound guidance|PROCEDURE: Artery puncture without ultrasound guidance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Neurogenic Myocardial and Lung Injury in SAH Patients
Status: RECRUITING
Conditions: Myocardial Injury|Lung Injury|Subarachnoid Hemorrhage
Interventions: DIAGNOSTIC_TEST: hs-TnT (high-sensitive cardiac troponin T) plasma concentration|DIAGNOSTIC_TEST: CK-MB (creatine kinase myocardial band) plasma concentration|DIAGNOSTIC_TEST: CPK (creatine phosphokinase) plasma concentration|DIAGNOSTIC_TEST: NT-proBNP (N-terminal prohormone of brain natriuretic peptide) plasma concentration|DIAGNOSTIC_TEST: Metanephrine concentration in urine
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Imatinib Standard Dose (400 mg/Day) Versus Imatinib High Dose (800 mg/Day)
Status: COMPLETED
Conditions: Chronic Myeloid Leukemia
Interventions: DRUG: STI571 (400 mg/day; or 800 mg/day)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Phase Ib/II Study of Almonertinib Combined With SHR-1701 in the Treatment of Relapsed or Advanced Non-small Cell Lung Cancer
Status: NOT_YET_RECRUITING
Conditions: Relapsed or Advanced Non-small Cell Lung Cancer
Interventions: DRUG: Almonertinib combined with SHR-1701|DRUG: Almonertinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effect of Co-administration on the Pharmacokinetics of SPR720, Azithromycin, and Ethambutol in Healthy Participants
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: SPR720|DRUG: Azithromycin|DRUG: Ethambutol
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: FOR46 in Combination With Enzalutamide in Patients With Metastatic Castration Resistant Prostate Cancer
Status: RECRUITING
Conditions: Metastatic Castration-resistant Prostate Cancer|Prostate Cancer
Interventions: BIOLOGICAL: FOR46|BIOLOGICAL: Enzalutamide|DRUG: Pegfilgrastim
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Nexium on Transmucosal Esophageal Leak
Status: UNKNOWN
Conditions: Reflux|Esophagitis|Barrett's Esophagus
Interventions: DRUG: Esomeprazole (Nexium) 40 mg/day
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study of Rapamycin and Trastuzumab for Patients With HER-2 Receptor Positive Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Rapamycin|DRUG: Trastuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Thoracic Epidural Pressure in the Prone and Lateral Decubitus Position
Status: COMPLETED
Conditions: Thoracic Epidural Injection
Interventions: PROCEDURE: thoracic epidural catheterization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Jacobson Relaxation Technique and Pranayama Technique in Patients With COPD
Status: COMPLETED
Conditions: COPD|Shortness of Breath|Quality of Life|Cough
Interventions: PROCEDURE: Jacobsons Breathing Technique|PROCEDURE: Pranayama Technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of Dry Needling Treatment in Patients With Shoulder Myofascial Pain Syndrome
Status: NOT_YET_RECRUITING
Conditions: Shoulder Pain
Interventions: OTHER: Real dry needling|OTHER: Sham dry needling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT