pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: ProLOVE - Prospective Randomized Study of Midline Incisional Hernia Treatment
Status: COMPLETED
Conditions: HERNIA, VENTRAL
Interventions: PROCEDURE: Retromuscular Mesh repair of midline incisional hernia|PROCEDURE: Laparoscopic repair of midline incisional hernia
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A "Real World" Trial to Determine Efficacy and Health Outcomes of Toujeo (ACHIEVE CONTROL REAL LIFE STUDY PROGRAM)
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Insulin glargine, 300 U/ml|DRUG: Insulin glargine, 100 U/ml|DRUG: Insulin detemir|DRUG: Background Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility and Safety of Extraperitoneal Laparoscopic Extended Retroperitoneal Lymph Node Dissection at Time of Nephroureterectomy for Upper Tract Urothelial Carcinoma
Status: UNKNOWN
Conditions: Upper Tract Urothelial Carcinoma
Interventions: PROCEDURE: extraperitoneal laparoscopic extended retroperitoneal lymph node dissection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Drug Interaction Between Paracetamol and Warfarin
Status: COMPLETED
Conditions: Deep Venous Thrombosis|Pulmonary Embolism|Atrial Fibrillation|Stroke|Antiphospholipid Syndrome
Interventions: DRUG: paracetamol|DRUG: paracetamol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SCREENING
Clinical trial: Salivary Gland Surgery Before Radiation Therapy in Preventing Radiation-Caused Xerostomia in Patients With Head and Neck Cancer
Status: COMPLETED
Conditions: Head and Neck Cancer|Radiation Toxicity|Xerostomia
Interventions: PROCEDURE: salivary gland transfer|RADIATION: Post-operative radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Tirzepatide for Weight Loss Intervention in Early-Stage Hormone Receptor Positive/HER2 Negative Breast Cancer
Status: NOT_YET_RECRUITING
Conditions: Hormone Receptor-Positive Breast Cancer|HER2-Negative Breast Cancer
Interventions: DRUG: Tirzepatide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics, and Immunogenicity of JNJ-63723283, an Anti-Programmed Cell Death (PD)-1 Monoclonal Antibody, as Monotherapy or in Combination With Erdafitinib in Japanese Participants With Advanced Solid Cancers
Status: COMPLETED
Conditions: Neoplasm
Interventions: DRUG: JNJ-63723283|DRUG: Erdafitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Using a Wireless Controller to Deliver a Lighting Intervention to Persons With Dementia
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DEVICE: Active lighting intervention|DEVICE: Control lighting intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Enteral Nutrition on Stress Ulcer Hemorrage. Multicenter Randomized Controlled Trial
Status: UNKNOWN
Conditions: Enteral Nutrition|Gastro Intestinal Bleeding|Stress Ulcer Prophylaxis|Proton Pump Inhibitor
Interventions: DRUG: enteral nutrition + proton pump inhibitor|OTHER: enteral nutrition only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Protein Consumption and Resistance Training on Body Composition, Muscular Strength and Functional Capacity in the Elderly
Status: COMPLETED
Conditions: Elderly|Sarcopenia
Interventions: DIETARY_SUPPLEMENT: Exercise training + whey protein|OTHER: Exercise training + placebo (maltodextrin)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Use of Cannabinoid Patch for Knee Osteoarthritis
Status: WITHDRAWN
Conditions: Knee Osteoarthritis|CBD|Osteoarthritis
Interventions: DRUG: Topical CBD Patch|OTHER: Placebo Patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of beta2-Microglobulin Removal by Standard Versus New High Cut-Off Haemodialysis Membrane
Status: COMPLETED
Conditions: Renal Dialysis
Interventions: OTHER: Larger pore haemodialysis membrane|OTHER: Standard haemodialysis membrane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects on Experimental Dyspnea of High Flow Nasal Cannula
Status: COMPLETED
Conditions: Dyspnea|Healthy Volunteers
Interventions: DEVICE: Optiflow with an inspired fraction of oxygen of 100%|DEVICE: Optiflow with an inspired fraction of oxygen of 21%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Inolitazone Dihydrochloride and Paclitaxel in Treating Patients With Advanced Anaplastic Thyroid Cancer
Status: COMPLETED
Conditions: Anaplastic Thyroid Cancer|Recurrent Thyroid Cancer
Interventions: DRUG: efatutazone|DRUG: paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial Investigating the Pharmacokinetics and Pharmacodynamics of NNC0123-0000-0338 in a Tablet Formulation With Three Different Coatings in Healthy Subjects
Status: COMPLETED
Conditions: Diabetes|Healthy
Interventions: DRUG: insulin 338 (GIPET I)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Simulated Amniotic Fluid In Preventing Feeding Intolerance and Necrotizing Enterocolitis VLBW Neonates
Status: UNKNOWN
Conditions: Necrotizing Enterocolitis
Interventions: DRUG: simulated amniotic fluid 20cc/kg/day enterally|DRUG: distilled water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study Evaluating 10 mg and 25 mg Doses of Etanercept in Patients With Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: etanercept
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Feasibility of a Campaign Intervention Compared to a Standard Behavioral Weight Loss Intervention in Overweight and Obese Adults
Status: COMPLETED
Conditions: Weight Loss
Interventions: BEHAVIORAL: Standard Behavioral Weight Loss Intervention (SBWL)|BEHAVIORAL: Campaign Intervention (CI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Evaluation of Non-invasive Acoustic Approach to Detect and Monitor Cerebral Vasospasm
Status: UNKNOWN
Conditions: Vasospasm, Intracranial|Subarachnoid Hemorrhage
Interventions: DEVICE: HS-1000
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Programmed Intermittent Bolus During Continuous Interscalene Nerve Block for Shoulder Arthroplasty
Status: RECRUITING
Conditions: Shoulder Arthroplasty|Shoulder Osteoarthritis|Pain Management
Interventions: DEVICE: Programmed Intermittent Bolus|DEVICE: Continuous Infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intravitreal Ozurdex After Pars Plana Vitrectomy for Proliferative Diabetic Retinopathy
Status: COMPLETED
Conditions: Proliferative Diabetic Retinopathy
Interventions: DRUG: Intravitreal dexamethasone implant|PROCEDURE: Vitrectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Meibomian Gland Dysfunction Management
Status: ACTIVE_NOT_RECRUITING
Conditions: Contact Lens Discomfort|Meibomian Gland Dysfunction
Interventions: DEVICE: BlephEx|DEVICE: Manual debridement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tislelizumab in Combination With Anlotinib With ES-SCLC as Maintenance Therapy After First Line Chemotherapy
Status: UNKNOWN
Conditions: Small Cell Lung Carcinoma
Interventions: DRUG: Tislelizumab|DRUG: Anlotinib hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Glaucoma Adherence Study
Status: COMPLETED
Conditions: Ocular Hypertension|Primary Open Angle Glaucoma
Interventions: DRUG: Travoprost 0.004%/timolol 0.05% fixed combination eye drops (DuoTrav)|DEVICE: Travalert Dosing Aid
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of BIBW 2948 BS in COPD
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive|Bronchitis, Chronic
Interventions: DRUG: BIBW 2948 BS|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Prebiotics on Cognition and Health
Status: COMPLETED
Conditions: Physiological Stress|Cognitive Change|Gastrointestinal Health
Interventions: OTHER: Lactose Free 1% Milk|OTHER: Lactose Free 1% Milk + 10 g prebiotic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Pilot Trial of Interpersonal Psychotherapy for the Treatment of Depression in Patients With Prostate, Colorectal, Lung and Pancreatic Cancer
Status: TERMINATED
Conditions: Depression|Pancreatic Cancer|Lung Cancer|Colon Cancer|Prostate Cancer
Interventions: BEHAVIORAL: Psychotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Laparoscopic Pyelolithotomy Versus Percutaneous Nephrolothotomy for Management of >3cm Renal Pelvis Stone
Status: COMPLETED
Conditions: Renal Pelvis Stone >3cm
Interventions: PROCEDURE: laparoscopic pyelolithotomy|PROCEDURE: percutaneous nephrolithotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Online Treatment of Trichotillomania
Status: COMPLETED
Conditions: Trichotillomania|Alexithymia|Quality of Life
Interventions: BEHAVIORAL: Decoupling|BEHAVIORAL: Progressive relaxation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Real Life of Aflibercept In FraNce: oBservatiOnnal Study in Wet AMD
Status: COMPLETED
Conditions: Wet Macular Degeneration
Interventions: DRUG: Aflibercept (Eylea, VEGF Trap-Eye, BAY86-5321)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Measure Energy Expenditure and Food Intake in Participants With Obesity Using Tirzepatide
Status: COMPLETED
Conditions: Obesity
Interventions: DRUG: Tirzepatide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Efficacy of P6 Acupressure in Reducing Postoperative Nausea and Vomiting in Patients Undergoing Craniotomy
Status: COMPLETED
Conditions: Postoperative Nausea and Vomiting|Acupressure|Craniotomy
Interventions: DEVICE: P6 acupressure band|OTHER: Placebo band
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Clinical Trial to Investigate Safety and Efficacy of Edoxaban in Patients With CTEPH (KABUKI)
Status: COMPLETED
Conditions: CTEPH
Interventions: DRUG: Edoxaban|DRUG: Warfarin Potassium|DRUG: Warfarin Potassium placebo|DRUG: Edoxaban placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Impact of Ultraviolet Radiation on Bone Density and Muscle Strength in Postmenopausal Women
Status: COMPLETED
Conditions: Postmenopausal Osteoporosis
Interventions: DEVICE: Ultraviolet Radiation|BEHAVIORAL: Aerobic exercise|DIETARY_SUPPLEMENT: Vitamin D supplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: STELLAR-Rosuvastatin vs. Atorvastatin, Pravastatin, Simvastatin Across Dose Ranges
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DRUG: Rosuvastatin|DRUG: Atorvastatin|DRUG: Pravastatin|DRUG: Simvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MK0991 Versus Amphotericin B for Empirical Therapy in Febrile, Neutropenic Pediatric Patients (0991-044)
Status: COMPLETED
Conditions: Neutropenia|Fever
Interventions: DRUG: caspofungin acetate|DRUG: Comparator: AmBisome
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Tolerance of the Switch From Enfuvirtine to Raltegravir in Antiretroviral Therapy Regimen in HIV Patients With Undetectable Viral Load
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: FTC/TDF + EFV or LPV/R +T20|DRUG: FTC/TDF + EFV or LPV/R
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Daratumumab-bortezomib-dexamethasone (Dara-VCd) vs Bortezomib-Thalidomide-Dexamethasone (VTd), Then Maintenance With Ixazomib (IXA) or IXA-Dara
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: Daratumumab plus Velcade Cyclophosphamide Dexamethasone|DRUG: Velcade Thalidomide Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigating the Effect of Intravenous and Oral Tranexamic Acid on Blood Loss After Primary Hip and Knee Arthroplasty
Status: COMPLETED
Conditions: Primary Total Knee Arthroplasty|Primary Total Hip Arthroplasty
Interventions: DRUG: Tranexamic Acid 100 MG/ML|DRUG: Tranexamic Acid 500 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Magnetic Resonance Imaging and Computed Tomography in Patients With Stage I Seminoma of the Testicle
Status: UNKNOWN
Conditions: Testicular Germ Cell Tumor
Interventions: OTHER: questionnaire administration|PROCEDURE: computed tomography|PROCEDURE: magnetic resonance imaging|PROCEDURE: quality-of-life assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: DIAGNOSTIC
Clinical trial: A Comparative Study of Three Modes of Ventilation During CPB in Pediatrics With Pulmonary Hypertension Undergoing Congenital Heart Surgeries
Status: UNKNOWN
Conditions: Congenital Heart Disease|Pulmonary Hypertension
Interventions: DIAGNOSTIC_TEST: lung ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Magnesium-Based Trigger Point Injections for Relief of Chronic Myofascial Pelvic Pain
Status: TERMINATED
Conditions: Pelvic Pain
Interventions: PROCEDURE: Magnesium-Based Injection Formulation|PROCEDURE: Lidocaine-Only Injection Formulation|DRUG: lidocaine|DRUG: magnesium sulfate, bicarbonate, dextrose.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Theranostics of Radiolabeled Somatostatin Antagonists 68Ga-DOTA-JR11 and 177Lu-DOTA-JR11 in Patients With Neuroendocrine Tumors
Status: COMPLETED
Conditions: Neuroendocrine Tumors
Interventions: DEVICE: PET/CT Imaging|RADIATION: 68Ga-DOTA-JR11|RADIATION: 177Lu-DOTA-JR11
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Longitudinal Impact of Respiratory Viruses on Bronchiolitis Obliterans Syndrome After Allogeneic Hematopoietic Cell Transplantation (The RV-BOS Study)
Status: RECRUITING
Conditions: Bronchiolitis Obliterans Syndrome|Hematopoietic and Lymphoid Cell Neoplasm
Interventions: PROCEDURE: Home spirometry|PROCEDURE: Biospecimen Collection|OTHER: Questionnaire Administration
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Two Different Isoflavone Supplement Preparations on Gene-expression in Postmenopausal Women
Status: COMPLETED
Conditions: Postmenopause
Interventions: DIETARY_SUPPLEMENT: High daidzein supplement|DIETARY_SUPPLEMENT: High genistein supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Sitaxsentan in Proteinuric Chronic Kidney Disease
Status: UNKNOWN
Conditions: Chronic Kidney Disease|Proteinuria|Blood Pressure
Interventions: DRUG: Sitaxsentan|DRUG: Nifedipine|DRUG: Placebo tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An Immuno-Therapy Study of Experimental Medication BMS-986205 Given With Nivolumab With or Without Chemotherapy Compared to Chemotherapy in Participants With Previously Untreated Stage IV or Recurrent Non-Small Cell Lung Cancer
Status: WITHDRAWN
Conditions: Lung Cancer|Non-Small Cell Lung Cancer
Interventions: DRUG: BMS-986205|BIOLOGICAL: Nivolumab|DRUG: Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multiple Risk Factor Intervention Trial (Ms. FIT)
Status: RECRUITING
Conditions: Metabolic Disturbance|Sedentary Behavior
Interventions: BEHAVIORAL: Behavioural Experimental: guidelines-based physical activity|BEHAVIORAL: Behavioural Experimental: guidelines-based physical activity and healthy eating|BEHAVIORAL: Behavioural: Stretching exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Microencapsulated Propolis and Turmeric in Patients With Chronic Kidney Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Kidney Diseases|Inflammation
Interventions: DIETARY_SUPPLEMENT: Microcapsules with turmeric and propolis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Placebo-Controlled Clinical Nutrition Study of the Metabolic Effects of Food Product WBF-0011 in Type 2 Diabetes
Status: TERMINATED
Conditions: Type 2 Diabetes Mellitus
Interventions: OTHER: Medical Food Formulation 1|OTHER: Medical Food Formulation 2|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Acalabrutinib and Obinutuzumab for the Treatment of Previously Untreated Follicular Lymphoma or Other Indolent Non-Hodgkin Lymphomas
Status: RECRUITING
Conditions: Grade 1 Follicular Lymphoma|Grade 2 Follicular Lymphoma|Grade 3a Follicular Lymphoma|Indolent Non-Hodgkin Lymphoma|Lymphoplasmacytic Lymphoma|Lymphoproliferative Disorder|Mantle Cell Lymphoma|Marginal Zone Lymphoma
Interventions: DRUG: Acalabrutinib|BIOLOGICAL: Obinutuzumab|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Different Bowel Preparations for Colonoscopy In Children
Status: UNKNOWN
Conditions: Colonoscopy
Interventions: DEVICE: PEG-4000 with citrates and simethicone|DEVICE: polyethylene glycol 4000 solution with simethicon|DEVICE: polyethylene glycol 3350 hyper-osmotic solution with ascorbic acid|DEVICE: sodium picosulphate plus magnesium oxide and citric acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose:
Clinical trial: Cleaner Air for Lower Cardiometabolic Risk
Status: RECRUITING
Conditions: PreDiabetes
Interventions: DEVICE: PAC with HEPA filter intact|DEVICE: PAC with HEPA filter removed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Implantation of CEST and CESL MRI Methods for Detection of Breast Tumors
Status: NOT_YET_RECRUITING
Conditions: Malignant Tumor of Breast|Benign Breast Lumps|High-Risk Breast Cancer
Interventions: DEVICE: MRI scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Phase 2 Trial of the Safety and Efficacy of Bardoxolone Methyl in Patients With Rare Chronic Kidney Diseases - PHOENIX
Status: COMPLETED
Conditions: IgA Nephropathy|CKD Associated With Type 1 Diabetes|Focal Segmental Glomerulosclerosis|Autosomal Dominant Polycystic Kidney
Interventions: DRUG: Bardoxolone methyl capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multicenter Trial of a Topical Medication for Papulopustular Rosacea Applied Twice Daily Versus Once Daily
Status: COMPLETED
Conditions: Papulopustular Rosacea
Interventions: DRUG: azelaic acid 15% gel|DRUG: azelaic acid 15% gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Impact of Targeted Physical Activity on Clinically Debilitated Dialysis Patients.
Status: RECRUITING
Conditions: Frailty|Pain, Chronic|Dialysis; Complications|Kidney Diseases
Interventions: OTHER: Muscle Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Curcumin Formulation in Alzheimer's Disease
Status: TERMINATED
Conditions: Alzheimer Disease
Interventions: DIETARY_SUPPLEMENT: Curcumin Formulation|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Low-Dose Colchicine on Surrogate Markers of Cardiovascular Events in People Living With HIV Receiving Antiretroviral Therapy
Status: UNKNOWN
Conditions: HIV Infections|Inflammatory Markers|Colchicine Adverse Reaction
Interventions: DRUG: Low-dose colchicine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Initial Treatment With Elotuzumab, Carfilzomib, Lenalidomide and Dexamethasone in Multiple Myeloma
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: Elotuzumab|DRUG: Carfilzomib|DRUG: Lenalidomide|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Short-Term Fasting Before Chemotherapy in Treating Patients With Cancer
Status: COMPLETED
Conditions: Malignant Neoplasm
Interventions: OTHER: questionnaire administration|OTHER: preventative dietary intervention|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Revaluation of Wells' Clinical Prediction Score of Deep Vein Thrombosis (DVT) in Inpatients With Thromboprophylaxis Treatment
Status: COMPLETED
Conditions: Deep Vein Thrombosis|Thromboses, Venous
Interventions: DIAGNOSTIC_TEST: Doppler ultrasound
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Improving Neuroprotective Strategy for Ischemic Stroke With Sufficient Recanalization After Thrombectomy by Edaravone Dexborneol
Status: COMPLETED
Conditions: Stroke|Endovascular Thrombectomy
Interventions: DRUG: edaravone dexborneol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Propionic Acid on Regulatory T Cell Function in Children With CKD
Status: RECRUITING
Conditions: CKD (Chronic Kidney Disease) Stage 5D
Interventions: DIETARY_SUPPLEMENT: Sodium propionate|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of Postoperative Pain and Neuropathy at Cesarean Sectio With Blunt or Sharp Fascia Incision
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: PROCEDURE: sharp incision|PROCEDURE: blunt incision
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Adoptive Cell Therapy Across Cancer Diagnoses
Status: UNKNOWN
Conditions: Cancer
Interventions: BIOLOGICAL: Autologous tumor-infiltrating lymphocytes|DRUG: Ipilimumab|DRUG: Nivolumab|DRUG: proleukin|DRUG: Cyclophosphamide|DRUG: Fludara
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Hyaluronic Acid, PRP and Steroid Injections in Partial Rotator Cuff Tears: A Prospective Randomized Study
Status: UNKNOWN
Conditions: Partial Tear of Rotator Cuff|Rotator Cuff Tears
Interventions: COMBINATION_PRODUCT: Subacromial Injection (hyaluronic acid) + Physical Therapy.|COMBINATION_PRODUCT: Subacromial Injection (Platelet-Rich-Plasma) + Physical Therapy.|COMBINATION_PRODUCT: Subacromial Injection (methylprednisolone acetate) + Physical Therapy.|COMBINATION_PRODUCT: Subacromial Injection (Serum Saline) + Physical Therapy.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective Evaluation of the Quality of Life of Elderly Patients Undergoing Transfemoral Percutanous Aortic Valve Replacement (TAVI) for the Treatment of Severe Aortic Stenosis.
Status: RECRUITING
Conditions: Quality of Life|Aortic Valve Replacement|Transfemoral Approach
Interventions: OTHER: Quality of life questionnaire
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Impact of ExtraCorporeal Phototherapy (ECP) on Auxiliary Follicular T-lymphocytes and Circulating B-lymphocytes During Chronic AntiBody-Mediated Rejection in Kidney Transplantation.
Status: UNKNOWN
Conditions: Kidney Transplantation
Interventions: OTHER: Extracorporeal phototherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Ischemic Post-conditioning in the Treatment of Acute Ischemic Stroke
Status: RECRUITING
Conditions: Acute Ischemic Stroke|Large Vessel Occlusion|Intracranial Artery Occlusion With Cerebral Infarction|Endovascular Treatments
Interventions: DEVICE: Post-conditioning Balloon dilation and contraction
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Fibrinogen for Treatment of Pediatric Dilutional Coagulopathy. FibPaed Study.
Status: COMPLETED
Conditions: Blood Coagulation Disorders|Hemorrhage
Interventions: DRUG: Human fibrinogen concentrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Lifestyle Intervention of Obese Teenagers (LITE) Program
Status: COMPLETED
Conditions: Adolescent Obesity|Lifestyle Intervention
Interventions: BEHAVIORAL: LITE Program and Usual Care|BEHAVIORAL: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Influence of Oxytocin on Pair-bonding and Emotion Regulation
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Syntocinon-Spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of NX-2127 in Adults With Relapsed/Refractory B-cell Malignancies
Status: RECRUITING
Conditions: Chronic Lymphocytic Leukemia (CLL)|Small Lymphocytic Lymphoma (SLL)|Waldenstrom Macroglobulinemia (WM)|Mantle Cell Lymphoma (MCL)|Marginal Zone Lymphoma (MZL)|Follicular Lymphoma (FL)|Diffuse Large B-cell Lymphoma (DLBCL)|Primary Central Nervous System Lymphoma (PCNSL)
Interventions: DRUG: NX-2127
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Using of Biomarkers and Blood Culture in Early Detection of Systemic Infections
Status: NOT_YET_RECRUITING
Conditions: Invasive Fungal Infections
Interventions: DIAGNOSTIC_TEST: procalcitonin ,CRP and 1, 3- β -D- glucan in early diagnosis of invasive infections
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Evaluate the Effects of SAGE-718 in Participants With Parkinson's Disease Cognitive Impairment
Status: COMPLETED
Conditions: Parkinson Disease|Cognitive Dysfunction
Interventions: DRUG: SAGE-718|DRUG: SAGE-718-matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Pharmacodynamics of SHR-1707 in Alzheimer's Disease Patients
Status: RECRUITING
Conditions: Alzheimer's Disease
Interventions: DRUG: SHR-1707|DRUG: SHR-1707 placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Bed Rest Versus Moderate Activity in Preterm Premature Rupture of Membranes (PPROM)
Status: TERMINATED
Conditions: Preterm Premature Rupture of the Membranes|Physical Activity
Interventions: BEHAVIORAL: Moderate Activity
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Gemcitabine, Oxaliplatin, Tarceva &/or Cisplatin in HCC & Biliary Tree Cancers
Status: TERMINATED
Conditions: Hepatocellular Carcinoma|Cholangiocellular Carcinoma|Cholangiocarcinoma of the Extrahepatic Bile Duct|Bile Duct Cancer|Periampullary Adenocarcinoma|Gallbladder Cancer|Extrahepatic Bile Duct Cancer
Interventions: DRUG: Cisplatin|DRUG: Erlotinib|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Mindfulness Meditation on Physiological Response to Unpredictable Stimuli
Status: COMPLETED
Conditions: Anxiety Disorders|Generalized Anxiety Disorder|Social Anxiety Disorder|Panic Disorder|Post Traumatic Stress Disorder|Agoraphobia|Simple Phobia
Interventions: BEHAVIORAL: Mindfulness-Based Stress Reduction|BEHAVIORAL: Waitlist
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Improving Executive Functioning After Traumatic Brain Injury (TBI): A Trial of the "Short Term Executive Plus" Program
Status: COMPLETED
Conditions: Traumatic Brain Injury
Interventions: BEHAVIORAL: Immediate Start|BEHAVIORAL: Waitlist
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Study of Pembrolizumab (Keytruda®) and Trifluridine/Tipiracil (Lonsurf®) With Previously Treated Advanced Gastric Cancer
Status: NOT_YET_RECRUITING
Conditions: Gastric and Gastroesophageal Junction Adenocarcinoma
Interventions: DRUG: Pembrolizumab (Keytruda®), Trifluridine/Tipiracil (Lonsurf®)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Demineralised Bone Matrix (DBX) in Osteochondritis Dissecans (OCD)
Status: WITHDRAWN
Conditions: Osteochondritis Dissecans
Interventions: DEVICE: DBX Putty|PROCEDURE: Mosaicplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: In Vitro Maturation of Immature Oocytes
Status: COMPLETED
Conditions: Polycystic Ovary Syndrome|Ovarian Hyperstimulation Syndrome
Interventions: PROCEDURE: In Vitro Maturation of immature oocytes
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oxytocin Add-on Study for Stable Anxiety Patients
Status: TERMINATED
Conditions: Anxiety Disorders
Interventions: DRUG: Oxytocin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: MLN2704 in Subjects With Metastatic Androgen-Independent Prostate Cancer
Status: COMPLETED
Conditions: Prostatic Neoplasms
Interventions: DRUG: MLN2704 (DM1 conjugated monoclonal antibody MLN591)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Health Benefits of Indoor Air Filtration Among Children
Status: COMPLETED
Conditions: Protective Effect of Air Purifier on Children's Health
Interventions: BEHAVIORAL: Air Purifiers|BEHAVIORAL: Sham Air Purifiers
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Survival and Success of Two Different Filling Techniques
Status: RECRUITING
Conditions: Periapical Diseases|Bioceramic Sealers|Survival Rate|Healing Rate
Interventions: OTHER: bioceramic sealer group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Impact of Breath Exercises by Telemedicine in Patients Aged 8-18 Years With a Diagnosis of Asthma
Status: RECRUITING
Conditions: Allergic Asthma
Interventions: OTHER: respiratory exercises|OTHER: relaxation exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Prophylactic Cranial Irradiation (PCI) vs Observation in Stage III NSCLC
Status: COMPLETED
Conditions: Non Small Cell Lung Cancer (NSCLC)|Radical Treatment|Stage III Non-Small Cell Lung Cancer
Interventions: RADIATION: Prophylactic Cranial Irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigating the Effectiveness of Stereotactic Body Radiotherapy (SBRT) in Addition to Standard of Care Treatment for Cancer That Has Spread Beyond the Original Site of Disease
Status: RECRUITING
Conditions: Triple Negative Breast Cancer|Non Small Cell Lung Cancer|Metastatic Breast Cancer|Metastatic Non-Small Cell Lung Carcinoma
Interventions: RADIATION: Stereotactic Body Radiotherapy/SBRT|DRUG: Systemic Therapy/Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of GLB-001 in Patients With Myeloid Malignancies
Status: RECRUITING
Conditions: Polycythemia Vera|Essential Thrombocythemia|Myelofibrosis|Myelodysplastic Syndromes|Acute Myeloid Leukemia|Myeloid Malignancy
Interventions: DRUG: GLB-001
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 1, Dose-escalation Study of [225Ac]-FPI-2068 in Adult Patients With Advanced Solid Tumours
Status: RECRUITING
Conditions: Advanced Solid Tumor|Metastatic Colorectal Carcinoma|Head and Neck Squamous Cell Carcinoma|Non-small Cell Lung Cancer|Pancreatic Ductal Adenocarcinoma
Interventions: DRUG: FPI-2053|DRUG: [111In]-FPI-2107|DRUG: [225Ac]-FPI-2068
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Capsaicin on Salty Gustatory Cortices
Status: COMPLETED
Conditions: Volunteers
Interventions: DIETARY_SUPPLEMENT: Capsaicin|DIETARY_SUPPLEMENT: NaCl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study Evaluating The Pharmacokinetics (PK) And Safety Of Bosutinib In Subjects With Liver Disease And In Healthy Subjects
Status: COMPLETED
Conditions: Breast Cancer|Leukemia, Myeloid, Chronic
Interventions: DRUG: Bosutinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Therapy of Essential Hypertension With Kinzal®/ Kinzalplus®
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Telmisartan (Kinzal/Pritor, BAY68-9291)|DRUG: Telmisartan (Kinzal/Pritor, BAY68-9291) + Hydrochlorothiazide
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of a Live rNDV Based Vaccine Against COVID-19
Status: COMPLETED
Conditions: SARS-CoV-2 Infection
Interventions: BIOLOGICAL: Recombinant NDV Vectored Vaccine for SARS-CoV-2
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: HIV Prevention Among Vulnerable Male Youth
Status: COMPLETED
Conditions: Homosexuality, Male|HIV|Substance-related Disorders|Sexual Dysfunctions, Psychological
Interventions: BEHAVIORAL: MyPeeps Manualized Group Intervention|BEHAVIORAL: Standard Sexual Health Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Unrelated Umbilical Cord Blood Transplantation for Severe Aplastic Anemia and Hypo-plastic MDS Using CordIn(TM), Umbilical Cord Blood-Derived Ex Vivo Expanded Stem and Progenitor Cells to Expedite Engraftment and Improve Transplant Outcome
Status: RECRUITING
Conditions: Severe Aplastic Anemia|Hypo-Plastic MDS|Myelodysplastic Syndrome (MDS)
Interventions: BIOLOGICAL: Omidubicel (former CordIn)|DEVICE: Miltenyi CliniMACS(R) CD34 Reagent System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Single Ascending Doses Phase I Study to Evaluate the Safety and Pharmacokinetics of RBD4059 in Healthy Subjects
Status: RECRUITING
Conditions: Healthy Volunteers
Interventions: DRUG: RBD4059|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: LARGE Aneurysm Randomized Trial: Flow Diversion Versus Traditional Endovascular Coiling Therapy
Status: TERMINATED
Conditions: Intracranial Aneurysm
Interventions: PROCEDURE: Flow Diversion|PROCEDURE: Coiling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Additive Effects of Pravastatin and Valsartan
Status: COMPLETED
Conditions: Hypertension|High Cholesterol
Interventions: DRUG: pravastatin, valsartan, pravastatin+valsartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety and Efficacy of Androxal™ Treatment in Men With Secondary Hypogonadism
Status: COMPLETED
Conditions: Secondary Hypogonadism
Interventions: DRUG: Androxal|DRUG: Androxal|DRUG: AndroGel|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating for a Correlation Between Osteopathic Examination and Ultrasonography on Thoracic Spine Asymmetry
Status: COMPLETED
Conditions: Osteopathic Manipulative Treatment|Ultrasonography
Interventions: DIAGNOSTIC_TEST: Ultrasonography vs Osteopathic manipulative medicine structural exam
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Radiation Therapy, Pemetrexed Disodium, and Carboplatin in Treating Patients With Locally Advanced Esophageal Cancer That Can Be Removed By Surgery
Status: TERMINATED
Conditions: Esophageal Cancer
Interventions: DRUG: carboplatin|DRUG: Pemetrexed|PROCEDURE: conventional surgery|PROCEDURE: neoadjuvant therapy|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Visceral Adipokines Visfatin, Vaspin and Omentin Levels in Gestational Diabetes Mellitus Pregnant Women
Status: COMPLETED
Conditions: Gestational Diabetes|Obesity|Visceral Obesity
Interventions: DIAGNOSTIC_TEST: oral glucose tolerance test|DIAGNOSTIC_TEST: Blood sample
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Surgical Pleth Index (SPI) Guided Analgesia During Sevoflurane Anesthesia
Status: COMPLETED
Conditions: Balanced Anesthesia
Interventions: DRUG: administration of sufentanil|DRUG: sufentanil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial to Evaluate the Safety, Tolerability and Preliminary Effectiveness of Single Administration Intradiscal rhGDF-5 for the Treatment of Early Stage Lumbar Disc Degeneration
Status: COMPLETED
Conditions: Early Lumbar Disc Degeneration
Interventions: DRUG: Intradiscal rhGDF-5|DRUG: Vehicle control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Application of Carbon Dioxide for Identifying the Intersegmental Plane in Thoracoscopic Segmentectomy
Status: COMPLETED
Conditions: Lung Cancer|Pulmonary Nodule, Solitary|Segmentectomy|Pulmonary Nodule, Multiple
Interventions: PROCEDURE: 100% oxygen|PROCEDURE: Carbon dioxide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: OSI-7904L and Oxaliplatin in Treating Patients With Refractory or Recurrent Advanced Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: OSI-7904L|DRUG: oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Concordance Between Buccal Cavity Swab and Nasopharyngeal Swab for SARS-CoV-2 (COVID-19) Detection by RT-PCR and ELISA
Status: UNKNOWN
Conditions: Covid19
Interventions: DIAGNOSTIC_TEST: Test At Home's Proprietary "Lollipop" Buccal Cavity Swab
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Morphea in Adults and Children (MAC) Cohort Study: A Morphea Registry and DNA Repository
Status: RECRUITING
Conditions: Scleroderma, Localized|Morphea|Frontal Linear Scleroderma en Coup de Sabre|Scleroderma, Circumscribed|Scleroderma, Linear
Interventions: OTHER: Morphea
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Neuromuscular Characteristics of Strict Vegetarians and Non-Vegetarians Women
Status: RECRUITING
Conditions: Hypertrophy
Interventions: OTHER: 16 weeks of strength training protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Combination Study Of CP-751,871 With Paclitaxel And Carboplatin In Advanced Lung Cancer
Status: COMPLETED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: CP-751,871|DRUG: paclitaxel|DRUG: carboplatin|DRUG: CP-751,871|DRUG: paclitaxel|DRUG: carboplatin|DRUG: erlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Total Neoadjuvant Chemotherapy in Locally Advanced Gastric and Gastroesophageal Junction Cancer
Status: RECRUITING
Conditions: Gastric Cancer|Stomach Cancer|GastroEsophageal Cancer|Gastric Adenocarcinoma|Gastroesophageal Junction Adenocarcinoma|Advanced Gastric Adenocarcinoma|Gastric Neoplasm|Stomach Neoplasm|Gastrointestinal Cancer|Advanced Gastroesophageal Junction Adenocarcinoma|Advanced Gastric Carcinoma
Interventions: DRUG: Docetaxel|DRUG: Oxaliplatin|DRUG: Leucovorin|DRUG: Fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non-Invasive Monitoring Of Metabolite Levels Using Novel And Adapted MR Spectroscopy Techniques
Status: RECRUITING
Conditions: Magnetic Resonance Spectroscopy
Interventions: DEVICE: NIMM_MRS
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE