pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: SQ53 Disinfectant Wipes for Prevention of CRBSI
Status: COMPLETED
Conditions: Catheter-related Bloodstream Infection
Interventions: DEVICE: SQ53 Wipe|DEVICE: Ethanol Wipe
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: EGFR806-specific CAR T Cell Locoregional Immunotherapy for EGFR-positive Recurrent or Refractory Pediatric CNS Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Central Nervous System Tumor, Pediatric|Glioma|Ependymoma|Medulloblastoma|Germ Cell Tumor|Atypical Teratoid/Rhabdoid Tumor|Primitive Neuroectodermal Tumor|Choroid Plexus Carcinoma|Pineoblastoma
Interventions: BIOLOGICAL: EGFR806-specific chimeric antigen receptor (CAR) T cell
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Warfarin After Anterior ST-Elevation Myocardial Infarction
Status: COMPLETED
Conditions: Myocardial Infarction
Interventions: DRUG: aspirin + clopidogrel|DRUG: aspirin + clopidogrel + warfarin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of MCMV5322A/MCMV3068A for the Prevention of Cytomegalovirus Disease in High-Risk Kidney Allograft Recipients
Status: COMPLETED
Conditions: Cytomegalovirus Infections
Interventions: DRUG: MCMV3068A|DRUG: MCMV5322A|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Vasoactive Drugs in Intensive Care Unit
Status: RECRUITING
Conditions: Shock
Interventions: DRUG: Norepinephrine|DRUG: Epinephrine|DRUG: Phenylephrine|DRUG: Vasopressin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An Coach-based Intervention Study of an Extended Discharge Planning Program on Patients With COPD
Status: UNKNOWN
Conditions: Loss of Interest
Interventions: BEHAVIORAL: Tablet Computer Motivated Instruction|BEHAVIORAL: Systematic Instruction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Complete Revascularization Via Inferior Part-sternotomy
Status: NOT_YET_RECRUITING
Conditions: Complete Revascularization|Coronary Artery Bypass Grafting|Multivessel Coronary Artery Disease
Interventions: PROCEDURE: Inferior part-sternotomy|PROCEDURE: Full median sternotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Preeclampsia And Nonsteroidal Drugs for Analgesia: a Randomized Non Inferiority Trial
Status: RECRUITING
Conditions: Preeclampsia Severe|Preeclampsia Postpartum
Interventions: DRUG: Ibuprofen 600 mg|DRUG: Ketorolac|DRUG: Acetaminophen|DRUG: Oxycodone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Infliximab Plus Methotrexate for the Treatment of Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Placebo|DRUG: Infliximab 3 mg/kg|DRUG: Infliximab 10 mg/kg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Continuation of Patient Follow-up to 2 Years for the Pinnacle RSA and Pinnacle DM RSA Clinical Trials
Status: ACTIVE_NOT_RECRUITING
Conditions: Hip Osteoarthritis
Interventions: DEVICE: Pinnacle Gription Acetabular Cup|DEVICE: Pinnacle Dual Mobility
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigational Use of Erenumab for the Treatment of Fibromyalgia Pain
Status: TERMINATED
Conditions: Fibromyalgia
Interventions: DRUG: Erenumab|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Epidural Neostigmine for Labor Pain
Status: COMPLETED
Conditions: Labor Pain
Interventions: DRUG: Neostigmine|DRUG: Bupivacaine|DRUG: fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy/Safety of Sodium Stibogluconate (SSG) Versus Paromomycin (PM) and SSG/PM Combination to Treat V Leishmaniasis
Status: COMPLETED
Conditions: Visceral Leishmaniasis
Interventions: DRUG: Sodium Stibogluconate|DRUG: Paromomycin sulphate|DRUG: SSG and Paromomycin sulphate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fertility Restoration Using Autologous Mesenchymal Stem Cells
Status: COMPLETED
Conditions: Chronic Endometritis|Uterus; Scar|Uterine Synechiae|Fallopian Tube Obstruction
Interventions: BIOLOGICAL: Autologous mesenchymal stem cells|OTHER: standard treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Coaxial Smart Drain (Redax TM) in Uniportal-VATS
Status: COMPLETED
Conditions: Pleural Effusion|Video Assisted Thoracic Surgery|Chest Tubes
Interventions: PROCEDURE: 28Fr "coaxial smart drain" chest tube
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Dual Inhibition of EGFR Signalling Using the Combination of Cetuximab and Erlotinib
Status: UNKNOWN
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: Cetuximab|DRUG: Erlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Zenith® LP Abdominal Aortic Aneurysm (AAA) Post-Market Registry
Status: TERMINATED
Conditions: Abdominal Aortic Aneurysm|Aorto-iliac Aneurysm
Interventions: DEVICE: Zenith® Low Profile AAA Endovascular Graft
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy of Ticagrelor vs Clopidogrel in High-risk NSTE-ACS Patients Undergoing Early PCI
Status: UNKNOWN
Conditions: Acute Coronary Syndrome
Interventions: DRUG: Ticagrelor|DRUG: clopidogrel|DRUG: Aspirin|PROCEDURE: PCI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Venetoclax and Rituximab/Hyaluronidase Human in Relapsed/Refractory CLL
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Lymphocytic Leukemia
Interventions: DRUG: Venetoclax|DRUG: Rituximab|DRUG: Rituximab/Hyaluronidase Human
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open-label, Uncontrolled Postmarketing Study of Cell-derived A/H1N1 Influenza HA Vaccine in Japanese Elderly Subjects
Status: COMPLETED
Conditions: Swine-Origin Influenza A H1N1 Virus
Interventions: BIOLOGICAL: Emulsion, Cell Culture-based, influenza HA vaccine H1N1
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: QUILT-3.055: A Study of Combination Immunotherapies in Patients Who Have Previously Received Treatment With Immune Checkpoint Inhibitors
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-Small Cell Lung Cancer|Small Cell Lung Cancer|Urothelial Carcinoma|Head and Neck Squamous Cell Carcinoma|Merkel Cell Carcinoma|Melanoma|Renal Cell Carcinoma|Gastric Cancer|Cervical Cancer|Hepatocellular Carcinoma|Microsatellite Instability|Mismatch Repair Deficiency|Colorectal Cancer
Interventions: DRUG: N-803 + Pembrolizumab|DRUG: N-803 + Nivolumab|DRUG: N-803 + Atezolizumab|DRUG: N-803 + Avelumab|DRUG: N-803 + Durvalumab|DRUG: N-803 + Pembrolizumab + PD-L1 t-haNK|DRUG: N-803 + Nivolumab + PD-L1 t-haNK|DRUG: N-803 + Atezolizumab + PD-L1 t-haNK|DRUG: N-803 + Avelumab + PD-L1 t-haNK|DRUG: N-803 + Durvalumab + PD-L1 t-haNK
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transmuscular Quadratus Lumborum Block on Post-Operative Analgesia After Total Hip Arthroplasty
Status: UNKNOWN
Conditions: Quadratus Lumborum Block
Interventions: PROCEDURE: Quadratus lumborum Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Palliative Care on Quality of Life and Symptom Control in Patients With Stage I, Stage II, or Stage IIIA Non-Small Cell Lung Cancer That Can Be Removed by Surgery
Status: COMPLETED
Conditions: Lung Cancer
Interventions: OTHER: educational intervention|OTHER: medical chart review|OTHER: questionnaire administration|PROCEDURE: end-of-life treatment/management|PROCEDURE: psychosocial assessment and care|PROCEDURE: quality-of-life assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Olive Oil and Nampt on Postprandial Inflammation and Atherosclerosis in the Setting of Metabolic Syndrome
Status: COMPLETED
Conditions: Metabolic Syndrome
Interventions: DIETARY_SUPPLEMENT: Niacin|DIETARY_SUPPLEMENT: Saturated meal|DIETARY_SUPPLEMENT: Monounsaturated meal|DIETARY_SUPPLEMENT: Polyunsaturated meal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Clinical Trial to Evaluate the Immunogenicity and Safety of sIPV in a "2+1"Sequential Schedule With bOPV in Infants
Status: COMPLETED
Conditions: Poliomyelitis
Interventions: BIOLOGICAL: sIPV-sIPV-bOPV vaccination schedule|BIOLOGICAL: wIPV-wIPV-bOPV vaccination schedule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Active Bathing to Eliminate Infection (ABATE Infection) Trial
Status: COMPLETED
Conditions: Healthcare Associated Infections|Methicillin Resistant Staphylococcus Aureus|Multi Drug Resistant Organisms
Interventions: DRUG: Arm 2: Decolonization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Desensitization Protocol for Highly Sensitized Patients on the Waiting List for Kidney Transplant
Status: UNKNOWN
Conditions: End Stage Renal Disease
Interventions: DRUG: High dose IVIG and B cell depleting agents
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety, Tolerability and Preliminary Efficacy Evaluation of CC-90011 Given in Combination With Cisplatin and Etoposide in Subjects With First Line, Extensive Stage Small Cell Lung Cancer
Status: COMPLETED
Conditions: Small Cell Lung Carcinoma
Interventions: DRUG: CC-90011|DRUG: Cisplatin|DRUG: Carboplatin|DRUG: Etoposide|DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Digital Subtraction Radiography Evaluation of SMART Restoration With Partial Caries Removal in Primary Teeth
Status: COMPLETED
Conditions: Dental Caries Extending Into Dentine
Interventions: PROCEDURE: partial caries removal only at enamel dentin junction.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Efficacy and Safety Study of Rivaroxaban With Warfarin for the Prevention of Stroke and Non-Central Nervous System Systemic Embolism in Patients With Non-Valvular Atrial Fibrillation
Status: COMPLETED
Conditions: Atrial Fibrillation|Stroke|Embolism
Interventions: DRUG: Rivaroxaban|DRUG: Warfarin|DRUG: Matching placebo for Rivaroxaban arm (Warfarin placebo)|DRUG: Matching placebo for Warfarin arm (Rivaroxaban placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Weaving Healthy Families Program
Status: ACTIVE_NOT_RECRUITING
Conditions: Alcohol Abuse|Drug Use|Violence, Domestic|Child Abuse|Diet Modification|Health Behavior|Health Knowledge, Attitudes, Practice|Relationship, Family|Relation, Parent-Child|Emotional Stress
Interventions: BEHAVIORAL: Weaving Healthy Families Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: The Application of Real-Time Near-infrared Imaging in Gynecological Surgery
Status: RECRUITING
Conditions: Cervical Cancer|Ovarian Tumor|Endometrial Carcinoma|Uterine Myomatosis|Adenomyosis|Ovarian Cyst Benign|Ovarian Cyst Malignant|Endometriosis|Uterine Sarcoma
Interventions: OTHER: Intravenous ICG and Real-Time Near-infrared Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Caregiver-Guided Pain Management Training in Palliative Care
Status: COMPLETED
Conditions: Advanced Cancer
Interventions: BEHAVIORAL: Caregiver-guided pain management training (CG-PMT)|BEHAVIORAL: Enhanced treatment-as-usual (TAU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Percutaneous Hemodynamic Support With Impella 2.5 During Scar-related Ventricular Tachycardia Ablation
Status: COMPLETED
Conditions: Ventricular Tachycardia
Interventions: DEVICE: Circulatory Support System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: DAILIES TOTAL1® - Comparative Assessment of Tear Film Evaporation
Status: COMPLETED
Conditions: Refractive Error
Interventions: DEVICE: Delefilcon A contact lenses|DEVICE: Narafilcon A contact lenses|DEVICE: Somofilcon A contact lenses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Impact of Exercise Intervention on Physical Function Falls, and Physical Restraint for Long-term Care Residents
Status: COMPLETED
Conditions: Exercise Intervention|Protein Supplementation
Interventions: BEHAVIORAL: Comprehension Exercise Training|DIETARY_SUPPLEMENT: Placebo milk|DIETARY_SUPPLEMENT: Protein Supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Cemiplimab in Adults With Cervical Cancer
Status: COMPLETED
Conditions: Squamous Cell Carcinoma (SCC)|Recurrent or Metastatic, Platinum-refractory Cervical Cancer
Interventions: DRUG: Cemiplimab|DRUG: Investigator Choice (IC) Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adjunctive Role of PRF After Free Gingival Graft Harvesting - Case Series
Status: COMPLETED
Conditions: Platelets Rich Fibrin, Palatal Donor Tissue
Interventions: BIOLOGICAL: Platelets Rich Fibrin in healing of palatal donor tissue|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Telehealth Exercise Training in Peripheral Arterial Disease - TEXT-PAD
Status: COMPLETED
Conditions: Peripheral Arterial Disease|Intermittent Claudication|Behavior, Health|Exercise Intervention
Interventions: BEHAVIORAL: Exercise and Lifestyle Change
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Drug Interaction Study of Cilnidipine and Valsartan
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: C - V - C+V|DRUG: C - C+V - V|DRUG: V - C - C+V|DRUG: V - C+V - C|DRUG: C+V - C - V|DRUG: C+V - V - C
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Emodepside in Adolescents and Adults Infected With Hookworm
Status: COMPLETED
Conditions: Hookworm Infections
Interventions: DRUG: Emodepside|DRUG: Albendazole 400mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Extension to a Study on the Efficacy and Safety of Vildagliptin Compared to Metformin in Drug Naive Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: vildagliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: PANDORA: Paravertebral AdjuNctive DexamethasOne Palmitate Reducing Chronic Pain After Caridiac Surgery
Status: RECRUITING
Conditions: Chronic Postoperative Pain
Interventions: DRUG: Dexamethasone Palmitate|DRUG: Dexamethasone Sodium Phosphate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Videofluoroscopic Swallowing Study (VFSS)
Status: TERMINATED
Conditions: Stroke|Parkinson Disease|Multiple Sclerosis|Oropharyngeal Dysphagia|Alzheimer Disease|Dementia
Interventions: DEVICE: Dysphagia Detection System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: GORE Flow Reversal System and GORE Embolic Filter Extension Study
Status: COMPLETED
Conditions: Carotid Stenosis|Constriction, Pathologic|Carotid Artery Diseases|Cerebrovascular Disorders|Brain Diseases|Central Nervous System Diseases|Nervous System Diseases|Arterial Occlusive Diseases|Vascular Diseases|Cardiovascular Diseases|Pathological Conditions, Anatomical
Interventions: DEVICE: Gore Flow Reversal System|DEVICE: Gore Embolic Filter
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CW2IP2: Imaging and Diagnostic Assessments
Status: RECRUITING
Conditions: Tauopathies
Interventions: DIAGNOSTIC_TEST: Amyloid PET scan|DIAGNOSTIC_TEST: Brain MRI Scan|BEHAVIORAL: Neurologic exam
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of the Vascular Response to Percutaneous Coronary Intervention in Patients With Non-ST-elevation Acute Coronary Syndromes Using Intravascular Blood Sampling
Status: WITHDRAWN
Conditions: Non ST Segment Elevation Acute Coronary Syndrome
Interventions: DEVICE: The Liquid Biopsy System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: A Study to Evaluate the Safety, Tolerability and Efficacy of MT101-5 in Subjects With Early Parkinson's Disease
Status: NOT_YET_RECRUITING
Conditions: Parkinson's Disease
Interventions: DRUG: MT101-5
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Saline Hypertonic in Preschoolers
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: 7% Hypertonic Saline (HS)|DRUG: 0.9% Isotonic Saline (IS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Safety and Pharmacodynamic Study of Healthy Chinese Subjects Administered Sodium Zirconium Cyclosilicate (ZS)
Status: COMPLETED
Conditions: Hyperkalemia
Interventions: DRUG: Sodium Zirconium Cyclosilicate (ZS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Camrelizumab Plus Stereotactic Body Radiotherapy in R/M NPC
Status: RECRUITING
Conditions: Nasopharyngeal Carcinoma
Interventions: DRUG: Camrelizumab|RADIATION: Stereotactic body radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intravenous Immunoglobulin (IVIG, Bioven) Efficacy Assess for COVID-19 / SARS-CoV-2 Severe Pneumonia Complex Treatment
Status: COMPLETED
Conditions: Covid19|Pneumonia
Interventions: DRUG: IVIG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Muscular Endurance And Its Association With Neck Pain, Disability, Neck Awareness, And Kinesiophobia
Status: COMPLETED
Conditions: Cervical Disc Herniation
Interventions: OTHER: Pain Assessment|OTHER: Assessment of Muscular Endurance|OTHER: Assessment of Neck Awareness|OTHER: Assessment of Fear of Movement
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study to Assess the Efficacy and Safety of PT010 Relative to PT003 and PT009 in Subjects With Moderate to Very Severe COPD (Ethos)
Status: COMPLETED
Conditions: COPD
Interventions: DRUG: BGF MDI 320/14.4/9.6 μg|DRUG: GFF MDI 14.4/9.6 μg|DRUG: BGF MDI 160/14.4/9.6 μg|DRUG: BFF MDI 320/9.6 μg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vestibular Prognosis Assessment of ISSNHL With Vestibular Dysfunction Treated With Oral or Intratympanic Glucocorticoids
Status: UNKNOWN
Conditions: Vestibular Vertigo|Sudden Hearing Loss
Interventions: DRUG: Prednisone 5Mg Tab|DRUG: Methylprednisolone 40 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: To Evaluate the Optimum Dose of Platelet Rich Plasma in Knee Osteoarthritis and Compare Efficacy With Hyaluronic Acid
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: BIOLOGICAL: Platelet rich plasma|DRUG: Hyaluronic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Post-Exposure Prophylaxis for Asymptomatic SARS-CoV-2 COVID-19 Patients With choloroquinE Compounds
Status: TERMINATED
Conditions: SARS-CoV-2|Coronavirus Infection|Asymptomatic Condition|COVID-19
Interventions: DRUG: Hydroxychloroquine Sulfate Regular dose|DRUG: Hydroxychloroquine Sulfate Loading Dose|DRUG: Chloroquine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Methicillin-resistant Staphylococcus Aureus (MRSA) Skin and Soft Tissue Infection (SSTI) Prevention in Military Trainees
Status: COMPLETED
Conditions: Staphylococcus Aureus|MRSA Skin Infections|Staphylococcal Skin Infections
Interventions: DRUG: Chlorhexidine gluconate|OTHER: Supplemental training, education and hygiene
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: AM-125 in the Treatment of Acute Peripheral Vertigo Following Neurosurgery
Status: COMPLETED
Conditions: Vestibular Vertigo
Interventions: DRUG: Intranasal Drug|DRUG: Oral Tablet|OTHER: Intranasal Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Improving Mental Health Among the LGBTQ+ Community
Status: RECRUITING
Conditions: Anxiety|Depression
Interventions: BEHAVIORAL: Acceptance-Based Behavior Therapy (ABBT)|OTHER: Treatment-as-Usual (TAU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Factors Affecting Split Thickness Skin Graft Success Rates in Patients Who Underwent a Radial Forearm or Fibula Free Flap
Status: RECRUITING
Conditions: Skin Graft Complications
Interventions: OTHER: Cast and bolster placement duration|OTHER: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intubation With Different Angles of the Intubation Tube Using C-macr d Blade Videolaringoscope;
Status: COMPLETED
Conditions: Intubation; Difficult or Failed|Sore-throat|Hoarseness
Interventions: OTHER: Intubation using C-MAC D blade videolariyngoscope
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Prospective, One-arm and Open Clinical Study of CM313 in the Treatment of Immune Thrombocytopenia
Status: RECRUITING
Conditions: Immune Thrombocytopenia|Treatment
Interventions: DRUG: CM313 Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nivolumab in Epstein-Barr Virus (EBV)-Positive Lymphoproliferative Disorders and EBV-Positive Non-HodgkinLymphomas
Status: RECRUITING
Conditions: Epstein-Barr Virus Infections|Lymphoma|Lymphoproliferative Disorder|Disorders, Lymphoproliferative
Interventions: BIOLOGICAL: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comfort Study of Brinzolamide 1% / Brimonidine 0.2% Fixed Combination, Brinzolamide 1% and Brimonidine 0.2%
Status: COMPLETED
Conditions: Open-Angle Glaucoma|Ocular Hypertension
Interventions: DRUG: Brinzolamide 1%/brimonidine tartrate 0.2% ophthalmic suspension|DRUG: Brinzolamide ophthalmic suspension, 1%|DRUG: Brimonidine tartrate ophthalmic solution, 0.2%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Functional Outcomes and Quality of Life in Hip, Knee and Shoulder Arthroplasty
Status: COMPLETED
Conditions: Arthroplasty, Replacement, Hip|Arthroplasty, Replacement, Knee|Arthroplasty, Replacement, Shoulder
Interventions: OTHER: Questionnaire administration
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Acupuncture for Post-Operative Pain Control for Patients Undergoing Gynecological Surgery
Status: COMPLETED
Conditions: Post-operative Pain|Gynecological Surgery|Acupuncture
Interventions: DEVICE: Acupuncture needles
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Efficacy of a Global Dental Health Promotion Program on Dental Hygiene in Patients With Schizophrenia.
Status: TERMINATED
Conditions: Schizophrenia
Interventions: OTHER: Dental care education program|OTHER: Surveillance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: SARS-COV-2-Spike-Ferritin-Nanoparticle (SpFN) Vaccine With ALFQ Adjuvant for Prevention of COVID-19 in Healthy Adults
Status: UNKNOWN
Conditions: SARS-CoV-2 Infection
Interventions: BIOLOGICAL: 25 µg SpFN_1B-06-PL + ALFQ (QS21 Adjuvant)|DRUG: Sodium chloride, USP, for injection (0.9% NaCl)|BIOLOGICAL: 50 µg SpFN_1B-06-PL + ALFQ (QS21 Adjuvant)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Amitriptyline vs GON and SON Blocks in Migraine
Status: COMPLETED
Conditions: Migraine|Headache
Interventions: DRUG: Lidocaine 1% Injectable Solution|DRUG: Amitriptyline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Letrozole + Palbociclib Combination as Neoadjuvant Treatment of Stage II-IIIA PAM 50 ROR-defined Low or Intermediate Risk Luminal Breast Cancer, in Postmenopausal Women
Status: COMPLETED
Conditions: Neoadjuvant Operable Breast Cancer
Interventions: DRUG: Fluorouracile|DRUG: Epirubicin|DRUG: Cyclophosphamide|DRUG: Letrozole|DRUG: Palbociclib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ANRS 12372 MODERATO Study
Status: ACTIVE_NOT_RECRUITING
Conditions: HIV-1-infection
Interventions: DRUG: dolutegravir|DRUG: atazanavir boosted with ritonavir|DRUG: tenofovir + lamivudine +efavirenz or dolutegravir + lamivudine + tenofovir|DRUG: Lamivudine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Culturally Targeted & Individually Tailored Smoking Cessation Study: LGBT Smokers
Status: COMPLETED
Conditions: Cigarette Smoking
Interventions: BEHAVIORAL: Culturally Targeted Cessation Program|BEHAVIORAL: Non-Targeted Cessation Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Aprepitant on Satiation, Gastric Volume, Gastric Accommodation and Gastric Emptying
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Aprepitant|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Lipoprotein Effects of Substituting Beef Protein for Carbohydrate
Status: COMPLETED
Conditions: Healthy|Cardiovascular Disease|Atherogenic Dyslipidemia
Interventions: OTHER: High Carbohydrate, High Saturated Fat Diet|OTHER: Low Carbohydrate, High Saturated Fat Diet|OTHER: Low Carbohydrate, Low Saturated Fat Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of Two Different Techniques for Sinus Elevation, Open Versus Closed .
Status: COMPLETED
Conditions: Alveolar Ridge Augmentation|Sinus Floor Augmentation|Maxillary Sinus
Interventions: PROCEDURE: Closed Sinus Elevation|PROCEDURE: Open Sinus Elevation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Endoscopic Balloon Dilation Versus Endoscopic Stricturotomy for Short Crohn's Strictures
Status: RECRUITING
Conditions: Crohn Disease
Interventions: DEVICE: Endoscopic balloon dilation|DEVICE: Endoscopic stricturotomy with or without stricturoplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TheEffect of a Solution-FocusedApproach on Breastfeeding
Status: RECRUITING
Conditions: Postpartum|Breastfeeding|Self Efficacy
Interventions: BEHAVIORAL: solution oriented approach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pharmacokinetics and Safety of Subcutaneous CSL324 in Healthy Japanese and White Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: BIOLOGICAL: CSL324|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Healthy People Initiative: Building the Socio-Economic Capital of Low Income Population At-Risk for HIV and Hepatitis-C
Status: RECRUITING
Conditions: Nicotine Dependence|Substance Use Disorders
Interventions: BEHAVIORAL: Life skills, training, education and work/volunteer opportunities|BEHAVIORAL: Standard Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: An Open-Label, Extension Study Evaluating the Safety, Toleration, and Efficacy of Sildenafil in Women With Sexual Arousal Disorder
Status: COMPLETED
Conditions: Sexual Dysfunctions, Psychological|Sexual Arousal Disorder
Interventions: DRUG: sildenafil
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Conventional Dose Protocol vs Low Dose Protocol Albumin Use in Patients With Cirrhosis and High Risk Spontaneous Bacterial Peritonitis
Status: RECRUITING
Conditions: Liver Cirrhosis|Spontaneous Bacterial Peritonitis
Interventions: BIOLOGICAL: 20% High Dose Albumin|OTHER: Standard Medical Treatment|BIOLOGICAL: 20% Reduced Dose Albumin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Dietary Supplements Based on Trace Elements on Voice Parameters and Some Psychological and Physiological Parameters Related to Stress - Single-center, Comparative, Cross-over, Randomized, Double-blind Study Versus Placebo, in Healthy Subjects
Status: COMPLETED
Conditions: Stress
Interventions: DIETARY_SUPPLEMENT: Nutri VX 1|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Continuation Booster Trial After a Vaccine Combining Tyrosinase/GP100/MART-1 Peptides Emulsified With Montanide ISA 51 With or Without GM-CSF for Patients With Melanoma
Status: TERMINATED
Conditions: Melanoma
Interventions: BIOLOGICAL: Montanide ISA 51
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Anti-histamine in Prevention Systolic Hypotension After Protamine
Status: COMPLETED
Conditions: Protamine Adverse Reaction
Interventions: DRUG: Chlorpheniramine and ranitidine|DRUG: 0.9% Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The LAMA Trial: Laparoscopic Correction of Perforated Peptic Ulcer Versus Open Correction
Status: COMPLETED
Conditions: Perforated Peptic Ulcer
Interventions: PROCEDURE: laparoscopic surgery|PROCEDURE: Upper laparotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: ALLPS VERSUS PVO Randomized Controlled Trial
Status: TERMINATED
Conditions: Liver Tumors Not Resectable in One Surgical Procedure
Interventions: PROCEDURE: Associating liver partition and portal vein ligation for staged hepatectomy|PROCEDURE: Portal vein embolization or ligation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Open Label Phase I/II Study of Dopamine Transporter Receptor Occupancy With OROS and Immediate Release Methylphenidate as Measured With C-11 Altropane in Human Subjects
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: OROS methylphenidate hydrochloride|DRUG: immediate release methylphenidate hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose:
Clinical trial: Root Coverage Comparing an Allograft to a Bovine Xenograft
Status: WITHDRAWN
Conditions: Gingival Recession
Interventions: PROCEDURE: Tunnel + AlloDerm|PROCEDURE: Tunnel + Novomatrix
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Oral D-Ribose in "Baby Boomers" With Fatigue. A Randomized, Double-Blind Study
Status: COMPLETED
Conditions: Fatigue
Interventions: DIETARY_SUPPLEMENT: D-ribose|DIETARY_SUPPLEMENT: Dextrose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Development and Evaluation of "Period Kits" for Adolescents With Intellectual and Developmental Disabilities
Status: COMPLETED
Conditions: Autistic Spectrum Disorder|Patient Empowerment|Menstrual Discomfort
Interventions: OTHER: Period Kit
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Method of Clopidogrel Pre-treatment Undergoing Conventional Coronary Angiogram in Angina Patients
Status: COMPLETED
Conditions: Angina, Stable
Interventions: DRUG: clopidogrel 75mg|DRUG: Clopidogrel 300 mg|DRUG: clopidogrel 600mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Tadalafil, Sildenafil and Pentoxyfylline on Frozen Embryo Transfer Outcomes
Status: NOT_YET_RECRUITING
Conditions: IVF
Interventions: DRUG: tadalafil|DRUG: Sildenafil|DRUG: pentoxifylline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study of PH3 for the Prevention of Osteoporosis in Postmenopausal Women
Status: COMPLETED
Conditions: Osteoporosis
Interventions: DRUG: PH3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Dysport Dose-Ranging Treatment of Platysmal Bands
Status: ACTIVE_NOT_RECRUITING
Conditions: Platysma Bands
Interventions: DRUG: AbobotulinumtoxinA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Health Education by Buddhist Monks to Promote Malaria Knowledge and Preventive Practices in Rural Myanmar
Status: COMPLETED
Conditions: Buddhist Monks|Health Education|Malaria|Monastery-based|Myanmar|Preventive Practice
Interventions: BEHAVIORAL: Monastery-based health education by Buddhist monks
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Sunphenon Epigallocatechin-Gallate (EGCg) in Duchenne Muscular Dystrophy
Status: COMPLETED
Conditions: Duchenne Muscular Dystrophy
Interventions: DRUG: Epigallocatechin-Gallate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mental Practice (MP) Combined With Transcranial Direct Current Stimulation (tDCS) on Motor Learning in the Elderly
Status: UNKNOWN
Conditions: Neuron Degeneration
Interventions: DEVICE: Transcranial stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of Oxygen Adminstration by Nasal Cannula and High Flow Cannula During Bronchoscopy
Status: COMPLETED
Conditions: Respiratory Disease
Interventions: DEVICE: Oxygen administration with Common nasal cannula|DEVICE: Oxygen administration with high flow nasal cannula, device Airvo2 Fisher and Pykel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Prophylaxis Against Postoperative Nausea and Vomiting After Laparoscopic Cholecystectomy
Status: RECRUITING
Conditions: Postoperative Nausea and Vomiting|Laparoscopic Cholecystectomy
Interventions: DRUG: Ondansetron 4mg + dexmedetomidine 0.5 ug/kg + normal saline .|DRUG: Ondansetron 4mg + dexamethasone 8mg + normal saline.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Three-way Crossover Study Comparing Ondansetron ODFS Administered With and Without Water to Zofran ODT Without Water
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DRUG: Ondansetron 8 mg ODFS without water|DRUG: Ondansetron 8 mg ODFS with water|DRUG: Zofran ODT (ondansetron 8 mg) without water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Human Factors Study of Methotrexate Prefilled Pen (50 mg/mL) in Patients With Juvenile Idiopathic Arthritis
Status: COMPLETED
Conditions: Juvenile Idiopathic Arthritis
Interventions: DEVICE: methotrexate prefilled pen
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Clinical Trial For The Treatment Of Chronic Chagas Disease With Posaconazole And Benznidazole
Status: COMPLETED
Conditions: Chagas Disease
Interventions: DRUG: Benznidazole|DRUG: Posaconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating the Onset-of-Action, Safety, and Efficacy of RDX227675 for the Treatment of Hyperkalemia
Status: TERMINATED
Conditions: Hyperkalemia
Interventions: DRUG: RDX227675|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: PsA Secukinumab XCT Structural Progression Study
Status: COMPLETED
Conditions: Psoriatic Arthritis
Interventions: DRUG: Secukinumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess Adverse Events and Change in Disease Activity of Intramuscular AGN-151586 Injection in Adult Participants With Glabellar Lines
Status: COMPLETED
Conditions: Glabellar Lines
Interventions: DRUG: Placebo|DRUG: AGN-151586
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Web-based Training and Telephone Follow-up of Patients With Heart Failure: Randomized Controlled Trial
Status: COMPLETED
Conditions: Heart Failure|Patient|Quality of Life|Symptoms
Interventions: BEHAVIORAL: web-based training and telephone monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Immersive Virtual Reality to Reduce Procedural Pain During IV Insertion in Children in the Emergency Department
Status: COMPLETED
Conditions: IV Insertion in the Emergency Department
Interventions: DEVICE: Virtual Reality Program|DEVICE: iPad Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: LTS of Siliq vs. Other Therapies Treating of Adults With Moderate-to-Severe Psoriasis
Status: ENROLLING_BY_INVITATION
Conditions: Psoriasis
Interventions: BIOLOGICAL: Brodalumab|DRUG: Comparator Drug (non-biologic IL-17 inhibitors)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Prevalence of Dissociative Identity Disorder in At-risk Outpatient Groups Reporting Childhood Trauma.
Status: RECRUITING
Conditions: Dissociative Disorder
Interventions: DIAGNOSTIC_TEST: psychometric assessment|DIAGNOSTIC_TEST: semi-structured clinical interview
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Postoperative Radiotherapy of Non-small Cell Lung Cancer: Accelerated vs. Conventional Fractionation
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer
Interventions: RADIATION: conventional fractionation|RADIATION: accelerated fraction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High-Dose Chemotherapy and Radiation Therapy Followed by Peripheral Stem Cell Transplantation in Treating Patients With Acute Leukemia in Remission
Status: COMPLETED
Conditions: Bone Marrow Ablation|Leukemia
Interventions: BIOLOGICAL: filgrastim|DRUG: etoposide|PROCEDURE: peripheral blood stem cell transplantation|RADIATION: low-LET electron therapy|RADIATION: low-LET photon therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic and Tolerability Study of NFC-1 in Subjects Aged 6-17 Years With ADHD
Status: COMPLETED
Conditions: Attention Deficit Disorder With Hyperactivity
Interventions: DRUG: NFC-1 100 mg|DRUG: NFC-1 200 mg|DRUG: NFC-1 400 mg|DRUG: NFC-1 800 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Follow-up of Symptomless Inguinal and Ventral Hernias
Status: COMPLETED
Conditions: Hernia, Inguinal|Hernia, Ventral|Laparoscopy
Interventions: PROCEDURE: laparoscopic surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Phase 2A Evaluation of the Safety, Tolerability, Pharmacokinetics, Efficacy of Clofazimine (CFZ) in Cryptosporidiosis
Status: TERMINATED
Conditions: Cryptosporidiosis
Interventions: DRUG: Clofazimine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Intravenous Treatment of Tuberculosis
Status: TERMINATED
Conditions: Tuberculosis, Pulmonary
Interventions: DRUG: Isoniazid|DRUG: Rifampicin|DRUG: Ethambutol|DRUG: Rifampicin|DRUG: Isoniazid|DRUG: Ethambutol
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p