pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Single and Multiple Dose Study of Miricorilant (CORT118335) Tablet Formulations in Healthy Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Miricorilant 300 mg tablets|DRUG: Miricorilant 150 mg tablets|DRUG: Placebo 150 mg tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Hemodynamic Effects of Methylene Blue vs Hydroxocobalamin in Patients at Risk of Vasoplegia During Cardiac Surgery
Status: WITHDRAWN
Conditions: Vasoplegia|Hypotension|Coronary Artery Disease|Cardiac Valve Disease
Interventions: DRUG: Hydroxocobalamin|DRUG: Methylene Blue|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ABT-510 in Treating Patients With Metastatic Melanoma
Status: COMPLETED
Conditions: Melanoma (Skin)
Interventions: DRUG: ABT-510|OTHER: immunoenzyme technique|OTHER: immunohistochemistry staining method|OTHER: laboratory biomarker analysis|OTHER: pharmacological study|PROCEDURE: biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Legume Intake on Cardiovascular Risk Factors Among Adults at Risk for Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: OTHER: nutritional intervention|OTHER: life style modification
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study of Activated Cytokine-induced Killer Armed With Bispecific Antibody for Advanced Kidney Cancer
Status: WITHDRAWN
Conditions: Advanced Kidney Cancer
Interventions: BIOLOGICAL: Activated CIK and CD3-MUC1 Bispecific Antibody in Treating Kidney Cancer|PROCEDURE: cryotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Repetitive Transcranial Magnetic Stimulation in Spatial Attention After Stroke
Status: UNKNOWN
Conditions: Stroke
Interventions: DEVICE: r-TMS|DEVICE: SHAM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Healthy Lifestyle Promotion as Adjunctive Teletherapy for Treatment-resistant Major Depression
Status: UNKNOWN
Conditions: Depressive Disorder, Treatment-Resistant
Interventions: BEHAVIORAL: Lifestyle change promotion program|BEHAVIORAL: Mindfullness based cognitive program|BEHAVIORAL: Written Information
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CHUSPAN SCS BP Treatment of Churg-Strauss Syndrome Without Poor-Prognosis Factors
Status: UNKNOWN
Conditions: Churg-Strauss Syndrome
Interventions: DRUG: azathioprine|DRUG: cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neuroblastoma Protocol 2008: Therapy for Children With Advanced Stage High Risk Neuroblastoma
Status: TERMINATED
Conditions: Neuroblastoma
Interventions: DRUG: Temsirolimus|DRUG: Irinotecan|PROCEDURE: Surgical Resection of Primary Tumor|DRUG: Cyclophosphamide|DRUG: Doxorubicin|DRUG: Etoposide|DRUG: Cisplatin|DRUG: Topotecan|PROCEDURE: PBSC|RADIATION: Radiation Therapy|DRUG: 13-cis-retinoic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Metronidazole Gel and Mobile SMS Reminders on Gingivitis in Orthodontic Patients
Status: COMPLETED
Conditions: Gingivitis
Interventions: DRUG: Metronidazole gel|OTHER: SMS text reminder|OTHER: Placebo gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Guanidinoacetic Acid (GAA) Administration in Physically Active Men and Women
Status: COMPLETED
Conditions: Athletic Performance
Interventions: DIETARY_SUPPLEMENT: guanidinoacetic acid|DIETARY_SUPPLEMENT: GAA-4|DIETARY_SUPPLEMENT: GAA-1|DIETARY_SUPPLEMENT: PLACEBO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Evaluate the Safety and Efficacy of Hetrombopag Olamine in Severe Aplastic Anemia （SAA） Patient
Status: COMPLETED
Conditions: Severe Aplastic Anemia
Interventions: DRUG: Hetrombopag Olamine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Solithromycin in the Treatment of Nonalcoholic Steatohepatitis Without Cirrhosis
Status: COMPLETED
Conditions: Nonalcoholic Steatohepatitis
Interventions: DRUG: solithromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Prospective Observational Study of Effect of Somatropin on Growth Hormone Deficient Adults
Status: COMPLETED
Conditions: Hypopituitarism|Pituitary Insufficiency|Growth Hormone Deficiency, Adult
Interventions: DRUG: Somatropin (rDNA origin)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Combination Bortezomib and Rituximab in Patients With Waldenstrom's Macroglobulinemia (WM)
Status: COMPLETED
Conditions: Waldenstrom's Macroglobulinemia
Interventions: DRUG: Bortezomib|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antibiotic Strategy and Asymptomatic Bacteriuria in the Context of Intra-vesical Botulinum Toxin A Injections.
Status: UNKNOWN
Conditions: Urinary Tract Disease
Interventions: PROCEDURE: Intra-vesical BoNTA injections
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testing the Effect of Taking Ruxolitinib and CPX-351 in Combination for the Treatment of Advanced Phase Myeloproliferative Neoplasms
Status: RECRUITING
Conditions: Essential Thrombocythemia|Myelofibrosis|Myeloproliferative Neoplasm|Polycythemia Vera|Secondary Acute Myeloid Leukemia
Interventions: PROCEDURE: Allogeneic Hematopoietic Stem Cell Transplantation|DRUG: Liposome-encapsulated Daunorubicin-Cytarabine|DRUG: Ruxolitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Iberdomide (CC-220) in Combination With Elotuzumab and Dexamethasone for Relapsed/Refractory Multiple Myeloma
Status: ENROLLING_BY_INVITATION
Conditions: Multiple Myeloma
Interventions: DRUG: Iberdomide|DRUG: Elotuzumab|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Physical Activity With Online Support for Individuals With Chronic Widespread Pain (CWP)
Status: COMPLETED
Conditions: Chronic Widespread Pain
Interventions: BEHAVIORAL: Physical exercise and online support|BEHAVIORAL: Physical exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Antimicrobial Efficacy of ALT005 Ophthalmic Prep Solution in Healthy Volunteers
Status: COMPLETED
Conditions: Infection Secondary to Surgical Procedure
Interventions: DRUG: ALT005 Ophthalmic Prep Solution|OTHER: saline control|DRUG: Betadine ophthalmic prep solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: DHA Supplementation and Pregnancy Outcome
Status: COMPLETED
Conditions: Pregnancy
Interventions: DIETARY_SUPPLEMENT: 600 mg DHA|DIETARY_SUPPLEMENT: 300 mg DHA|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Sensitivity and Specificity of SARS-CoV-2 Rapid Antigen Test Compared to RT-PCR Test
Status: COMPLETED
Conditions: Covid19|Rapid Antigen Test|SARS-CoV-2
Interventions: DIAGNOSTIC_TEST: Standard Q COVID-19 Ag - test, produced by SD Biosensor INC.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Low Level Laser (LED) Use to Increase Dental Implant Stability and Post Operative Analgesia
Status: UNKNOWN
Conditions: Implant|Analgesia
Interventions: DEVICE: OsseoPulse device (Light emitting diode technology)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase III Study of SM-13496 (Lurasidone HCl) in Patients With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: SM-13496 40mg|DRUG: SM-13496 80mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Protection by Remote Ischemic Preconditioning During Transcatheter Aortic Valve Implantation
Status: UNKNOWN
Conditions: Aortic Valve Stenosis
Interventions: PROCEDURE: Remote ischemic preconditioning (RIPC)|PROCEDURE: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study on Once Daily FTC, ddI, Efavirenz Combination in Antiretroviral Naive HIV Infected Adults
Status: COMPLETED
Conditions: HIV Infections|Antiretroviral Naive
Interventions: DRUG: emtricitabine, FTC (drug)|DRUG: didanosine, ddI (drug)|DRUG: efavirenz (drug)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Study of FS-1502 in Patients With HER2 Expressed Advanced Solid Tumors and Breast Cancer.
Status: ACTIVE_NOT_RECRUITING
Conditions: Solid Tumor|Breast Cancer
Interventions: DRUG: FS-1502
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Local Anaesthetic Infusion Rates on Nerve Block Duration
Status: TERMINATED
Conditions: Other Acute Postoperative Pain|Pain, Postoperative|Anaesthesia
Interventions: DRUG: Varying infusion rates of Ropivacaine 0.2%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Fermented Protaetia Brevitarsis Seulensis Powder on Alcohol-induced Liver Disease
Status: RECRUITING
Conditions: Alcoholic Liver Disease
Interventions: DIETARY_SUPPLEMENT: Fermented Protaetia brevitarsis seulensis powder group|DIETARY_SUPPLEMENT: Placebo group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: AZD7325 Single Ascending Dose Study in Healthy Male Japanese Subjects
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: AZD7325|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Denosumab in Subjects With Giant Cell Rich Tumors of Bone
Status: UNKNOWN
Conditions: Aneurysmal Bone Cysts|Giant Cell Granuloma|Osteoblastoma|Chondroblastoma|Chondromyxoid Fibroma
Interventions: DRUG: Denosumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Penthrox® Combined With a Standard Analgesia (SoC) in Adult Patients Admitted to the Emergency Department With Moderate to Severe Pain Associated With Trauma
Status: COMPLETED
Conditions: Pain, Acute
Interventions: DRUG: Methoxyflurane|DRUG: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nevirapine (NVP) Use to Prevent Mother-to-Child Transmission of HIV
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Nevirapine|DRUG: Nevirapine placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: A Trial of High Intensity Versus Low Intensity Neoadjuvant Chemoradiotherapy in Locally Advanced Rectal Cancer
Status: UNKNOWN
Conditions: Rectal Cancer
Interventions: DRUG: Oxaliplatin|DRUG: Capecitabine|RADIATION: Radiotherapy|PROCEDURE: Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy, Safety and Tolerability of Oral AK0901 in Children With ADHD
Status: NOT_YET_RECRUITING
Conditions: ADHD
Interventions: DRUG: AK0901 capsule|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Androgen Blockade and Progesterone Augmentation of Gonadotropin Secretion
Status: RECRUITING
Conditions: PCOS|Polycystic Ovary Syndrome
Interventions: DRUG: Micronized progesterone|DRUG: Placebo|DRUG: Flutamide|DRUG: Estradiol patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Phase III Clinical Trial of Fruquintinib in Patients With Advanced Non-small Cell Lung Cancer
Status: COMPLETED
Conditions: NSCLC
Interventions: DRUG: Fruquintinib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Participants With Squamous Cell Oesophageal Carcinoma Receiving Nivolumab as Part of an Early Access to Medicines Scheme (EAMS) Program in the United Kingdom
Status: COMPLETED
Conditions: Esophageal Squamous Cell Carcinoma
Interventions: BIOLOGICAL: Nivolumab
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Online Treatment Recovery Assistance for Concussion in Kids
Status: UNKNOWN
Conditions: Concussion|MTBI - Mild Traumatic Brain Injury
Interventions: DEVICE: Online Treatment Recovery Assistance for Concussion in Kids (OnTRACK)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: High-Frequency Repetitive Transcranial Magnetic Stimulation of the Right Dorsolateral Prefrontal Cortex in PTSD
Status: COMPLETED
Conditions: PTSD, Post Traumatic Stress Disorder
Interventions: OTHER: 10 Hz rTMS of the right dorsolateral prefrontal cortex|OTHER: 20 Hz rTMS of the right dorsolateral prefrontal cortex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Low-dose Hormone Therapy for Relief of Vasomotor Symptoms
Status: COMPLETED
Conditions: Vasomotor Symptoms|Hot Flashes
Interventions: DRUG: 0.5mg DRSP / 0.5mg E2 (BAY86-4891)|DRUG: 0.25mg DRSP / 0.5mg E2 (BAY86-4891)|DRUG: Estradiol (E2 0.3mg)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Biomarker Analysis of Castration-resistant Prostate Cancer Undergoing Treatment With Docetaxel Followed by Enzalutamide
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Cancer|Castration-resistant Prostate Cancer
Interventions: DRUG: Docetaxel|DRUG: Enzalutamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial to Compare Xifaxan to Vancomycin for the Treatment of Clostridium Difficile-Associated Diarrhea (CDAD)
Status: COMPLETED
Conditions: Clostridium Infections|Diarrhea
Interventions: DRUG: Rifaximin (Xifaxan)|DRUG: Vancomycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Antineoplaston Therapy in Treating Patients With Low-Grade Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Low-Grade Lymphoma
Interventions: DRUG: Antineoplaston therapy (Atengenal + Astugenal)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rehabilitation Research and Training Center for Traumatic Brain Injury Interventions--Teen Online Problem Solving Study
Status: COMPLETED
Conditions: Traumatic Brain Injury
Interventions: BEHAVIORAL: Teen Online Problem Solving (TOPS)|BEHAVIORAL: Teen Online Problem Solving--Teen Only (TOPS-TO)|BEHAVIORAL: Internet Resources Comparison (IRC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neuroimaging of Pavlovian Fear Conditioning Processes in Patients With Pathological Anxiety
Status: UNKNOWN
Conditions: Post Traumatic Stress Disorder|Anxiety Disorders|Panic Disorder|Social Phobia|Phobia
Interventions: BEHAVIORAL: Novelty facilitated extinction|BEHAVIORAL: Standard Extinction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Acute and Chronic Effects of Inhaled Steroids on Pulmonary Function in Persons With Spinal Cord Injury
Status: UNKNOWN
Conditions: Spinal Cord Injury
Interventions: DRUG: Mometasone furoate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating Piperacillin-Tazobactam on Certain Bacteria in Hematology and Oncology Units
Status: COMPLETED
Conditions: Gram-Positive Bacterial Infections|Escherichia Coli Infections|Klebsiella Infections
Interventions: DRUG: piperacillin-tazobactam
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Multicenter Evaluation of Memory Remediation After TBI With Donepezil
Status: ACTIVE_NOT_RECRUITING
Conditions: Traumatic Brain Injury|Memory Deficits
Interventions: DRUG: Donepezil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Frequency Effect of STN-DBS Through the Dual System on FOG in PD
Status: UNKNOWN
Conditions: Parkinson Disease
Interventions: DEVICE: Application of dual system in frequency A|DEVICE: Application of dual system in frequency B
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Magnesium and Metabolic Syndrome
Status: COMPLETED
Conditions: Diabetes Mellitus|High Blood Pressure|Hypomagnesemia
Interventions: DIETARY_SUPPLEMENT: Magnesium chloride|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Safety and Efficacy of CP-690,550 in Patients With Moderate to Severe Crohn's Disease
Status: COMPLETED
Conditions: Crohn's Disease
Interventions: DRUG: CP-690,550|DRUG: CP-690,550|DRUG: CP-690,550|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Minimum Effective Volume of Lidocaine-Bupivacaine for Subgluteal Block
Status: UNKNOWN
Conditions: Injuries to the Ankle and Foot
Interventions: OTHER: Subgluteal Nerve Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Donor Umbilical Cord Blood Transplant in Treating Patients With Hematologic Cancer
Status: COMPLETED
Conditions: Acute Lymphoblastic Leukemia|Acute Myeloid Leukemia|Aggressive Non-Hodgkin Lymphoma|Chronic Myelogenous Leukemia|Chronic Phase Chronic Myelogenous Leukemia|Indolent Non-Hodgkin Lymphoma|Lymphoma|Mixed Phenotype Acute Leukemia|Myelodysplastic Syndrome|Myeloproliferative Neoplasm|Recurrent Chronic Lymphocytic Leukemia|Recurrent Follicular Lymphoma|Recurrent Lymphoplasmacytic Lymphoma|Recurrent Mantle Cell Lymphoma|Recurrent Marginal Zone Lymphoma|Recurrent Plasma Cell Myeloma|Recurrent Small Lymphocytic Lymphoma|Recurrent T-Cell Non-Hodgkin Lymphoma|Refractory Chronic Lymphocytic Leukemia|Refractory Chronic Myelogenous Leukemia|Refractory Follicular Lymphoma|Refractory Hodgkin Lymphoma|Refractory Lymphoplasmacytic Lymphoma|Refractory Mantle Cell Lymphoma|Refractory Small Lymphocytic Lymphoma|T-Cell Non-Hodgkin Lymphoma
Interventions: PROCEDURE: Allogeneic Hematopoietic Stem Cell Transplantation|DRUG: Cyclophosphamide|DRUG: Cyclosporine|DRUG: Fludarabine Phosphate|OTHER: Laboratory Biomarker Analysis|DRUG: Mycophenolate Mofetil|RADIATION: Total-Body Irradiation|PROCEDURE: Umbilical Cord Blood Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Patient Specific Ablation Strategy for Atrial Fibrillation (AWARE-2): A Randomized Clinical Trial
Status: NOT_YET_RECRUITING
Conditions: Atrial Fibrillation|Catheter Ablation|Radiofrequency Catheter Ablation
Interventions: PROCEDURE: Cryoballoon ablation|PROCEDURE: Radiofrequency catheter ablation +EPS guided trigger and substrate ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Ablative Radiotherapy to Consolidate Maximal Systemic Response in Metastatic Prostate Cancer (ANCHOR-Prostate)
Status: RECRUITING
Conditions: Prostate Cancer Metastatic
Interventions: RADIATION: SABR|OTHER: no RT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Modified 45-degree Head-up Tilt Position in Cesarean Operation to the Success of Spinal Anesthesia
Status: UNKNOWN
Conditions: Regional Anesthesia Morbidity
Interventions: PROCEDURE: spinal anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial Comparing JDP-205 to Diphenhydramine Injection for the Treatment of Acute Urticaria
Status: COMPLETED
Conditions: Acute Urticaria
Interventions: DRUG: Test Drug (JDP-205)|DRUG: Active Control (Diphenhydramine)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II Study of Chlorambucil and Subcutaneous Rituximab in Patients With Extranodal MALT Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: MALT Lymphoma
Interventions: DRUG: Chlorambucil|DRUG: Rituximab i.v.|DRUG: Rituximab s.c.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improving Uptake of Pediatric Vaccines Through Religious Conferences and Vaccines-in-a-van in Aceh, Indonesia
Status: RECRUITING
Conditions: Vaccination
Interventions: BEHAVIORAL: Religious conferences|BEHAVIORAL: Vaccine-in-a-van
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Microtransplantation Versus Auto-SCT in ≥PR Multiple Myeloma Patients
Status: UNKNOWN
Conditions: Microtransplantation|Autologous Stem Cell Transplantation|Multiple Myeloma in Relapse
Interventions: PROCEDURE: stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sedation Management in Pediatric Patients With Acute Respiratory Failure (The RESTORE Study)
Status: COMPLETED
Conditions: Respiratory Insufficiency|Respiratory Distress Syndrome, Newborn|Lung Diseases
Interventions: BEHAVIORAL: Team approach to sedation management|BEHAVIORAL: Usual approach to sedation management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of PRO Onc Assay to Assess HER2 in Patients With Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: PROCEDURE: PRO Onc Assay and Treatment|DRUG: Trastuzumab|DRUG: Pertuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess Effectiveness and Safety of Fixed Dose Combination of Lopinavir/Ritonavir (LPV/r) in Human Immunodeficiency Virus Type 1 (HIV-1) Infected Patients After Switching From Kaletra in the Routine Clinical Settings of Russian Federation
Status: TERMINATED
Conditions: HIV-1 Infection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: An Open Label Study of a Peptide Vaccine in Patients With Stage IIb or IIIa Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Carcinoma, Non-Small-Cell Lung|Lung Neoplasm
Interventions: BIOLOGICAL: EP2101
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radiofrequency in the Treatment of Urinary Incontinence After Radical Prostatectomy
Status: RECRUITING
Conditions: Urinary Incontinence|Post Prostatectomy
Interventions: DEVICE: Radiofrequency
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Computer Assisted Cognitive Rehabilitation for Persons With Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: BEHAVIORAL: MAPSS-MS|OTHER: Usual Care plus computer games
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Reducing Pain in Four- to Six-month Old Infants Undergoing Immunization Using a Multi-modal Approach
Status: COMPLETED
Conditions: Pain From Immunization
Interventions: BEHAVIORAL: Tactile stimulation added to Standard care|BEHAVIORAL: Standard care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Efficacy of TOOKAD® (VTP) Versus Active Surveillance for Intermediate Risk Localized Prostate Cancer
Status: WITHDRAWN
Conditions: Localized Prostate Cancer
Interventions: DRUG: TOOKAD®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Olaratumab (LY3012207) in Participants With Soft Tissue Sarcoma
Status: COMPLETED
Conditions: Soft Tissue Sarcoma
Interventions: DRUG: Olaratumab|DRUG: Doxorubicin|RADIATION: External Beam Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combined Chelation Therapy in Patients With Transfusion Dependent Thalassemia and Iron Overload
Status: COMPLETED
Conditions: Thalassemia|Iron Overload
Interventions: DRUG: Combo Chelation with Deferasirox (Exjade) and Deferoxamine (DFO)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficiency of a Tight Monitoring by a Nurse Practitioner of Rheumatoid Arthritis (RA) Patients in Remission
Status: UNKNOWN
Conditions: Rheumatoid Arthritis
Interventions: OTHER: tight nursing follow-up
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Impact of DMSO Concentrations on Hematopoietic Recovery After Autologous HSC Transplantation.
Status: COMPLETED
Conditions: Multiple Myeloma|Lymphomas|Leukemias
Interventions: PROCEDURE: Cryopreservation of HSCs using 5% DMSO concentration|PROCEDURE: Cryopreservation of HSCs using 7,5% DMSO concentration|PROCEDURE: Cryopreservation of HSCs using 10% DMSO concentration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Strengthening Tourette Treatment OPtions Using TMS to Improve CBIT, a Double-blind, Randomized, Controlled Study
Status: RECRUITING
Conditions: Tourette Syndrome
Interventions: DEVICE: transcranial magnetic stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Tolerability and Safety of LAS41004 Formulations in a Psoriasis Plaque Test
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: LAS41004-IMP1|DRUG: LAS41004 IMP2|DRUG: LAS41004 IMP3|DRUG: LAS41004 IMP4|DRUG: LAS41004 IMP6|DRUG: LAS41004 IMP5
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Using mHealth Technology to Identify and Refer Surgical Site Infections in Rwanda
Status: COMPLETED
Conditions: Surgical Site Infection
Interventions: OTHER: SSI Screening Tool used in home visits by CHWs|OTHER: SSI Screening Tool used via phone call follow-up
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Hypopressive Effectiveness in Postural Control and Pelvic Floor.
Status: COMPLETED
Conditions: Pelvic Floor Disorders|Postural; Defect|Muscle Weakness
Interventions: OTHER: Hypopressive exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess Adverse Events and How Single and Multiple Ascending Doses of ABBV-903 Move Through the Body in Healthy Adults
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: ABBV-903|DRUG: Placebo for ABBV-903|DRUG: Itraconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Study of OBP-301 (Telomelysin™) in Combination With Pembrolizumab and SBRT in Patients With HNSCC With Inoperable, Recurrent or Progressive Disease
Status: TERMINATED
Conditions: Head and Neck Squamous Cell Carcinoma With Inoperable Recurrent or Progressive Disease
Interventions: DRUG: OBP-301|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Whey Protein' Supplementation and Exercise in Patients With Heart Failure
Status: UNKNOWN
Conditions: Heart Failure|Sarcopenia|Muscle Loss|Quality of Life
Interventions: DIETARY_SUPPLEMENT: whey protein
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Effect of Acupuncture for QoL in Gastric Cancer Patients Undergoing Adjuvant Chemotherapy: a Pilot Study
Status: COMPLETED
Conditions: Stomach Neoplasms
Interventions: PROCEDURE: acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Estrogen on Memory in Post-Menopausal Women and Patients With Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer Disease
Interventions: DRUG: Donepezil|DRUG: Estrogen|DRUG: Progesterone
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Study of Pharmacokinetics of a Single IV Dose of CB-238,618 in Subjects With Varying Degrees of Renal Impairment Compared to Healthy Subjects (MK-6183-001)
Status: COMPLETED
Conditions: Healthy Volunteers|Renal Impairment
Interventions: DRUG: MK-6183
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Peer Interventions for Preschoolers With Autism
Status: RECRUITING
Conditions: Autism Spectrum Disorder
Interventions: BEHAVIORAL: Stay-Play-Talk Basic|BEHAVIORAL: Stay-Play-Talk Plus|BEHAVIORAL: Stay-Play-Talk Advanced
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Prospective, Multicenter, and Exploratory Study of CMGV in the Treatment of Recurrent Adult AML and MDS-EB-2/Elder AML
Status: RECRUITING
Conditions: Recurrent Adult Acute Myeloid Leukemia|Myelodysplastic Syndrome|Adult Acute Myeloid Leukemia
Interventions: DRUG: CMGV
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Skin-to-Skin Contact Start Time in Newborns Sucking and Mother's Breastfeeding Willingness and Parent-Infant Attachment Associated
Status: UNKNOWN
Conditions: Mother-Child Relationship
Interventions: BEHAVIORAL: skin to skin contact 60 min group|BEHAVIORAL: skin to skin contact 20min group
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Evaluate the Survival Benefits of Zemplar Versus Calcijex in Subjects w/ Stage V Chronic Kidney Disease on Hemodialysis
Status: TERMINATED
Conditions: End-Stage Kidney Disease
Interventions: DRUG: Zemplar (paricalcitol injection)|DRUG: Calcijex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Paired Associative Stimulation in the Dorsolateral Prefrontal Cortex in Patients With Schizophrenia
Status: ACTIVE_NOT_RECRUITING
Conditions: Schizophrenia
Interventions: OTHER: Brain Stimulation via Transcranial Magnetic Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of FiAsp and Aspart During Postprandial Exercise in Adults With Type 1 Diabetes
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus
Interventions: DRUG: Insulin FiAsp|DRUG: Insulin Aspart|OTHER: 60-minutes postprandial exercise|OTHER: 120-minutes postprandial exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study Comparing Tiotropium (Spiriva) to Salmeterol (Serevent) Plus Fluticasone (Flixotide) in Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Tiotropium|DRUG: Salmeterol plus Fluticasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Physiotherapy in Hematopoietic Stem Cell Transplantation
Status: UNKNOWN
Conditions: Hematologic Malignancy|Stem Cell Transplantation
Interventions: OTHER: Physiotherapy in patients with stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Pharmacokinetic, Safety, Tolerability and Relative Bioavailability of Gepotidacin in Healthy Adult Male and Female Participants
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Gepotidacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy With or Without Radiation Therapy in Treating Patients With Recurrent Head and Neck Cancer That Cannot Be Removed By Surgery
Status: TERMINATED
Conditions: Head and Neck Cancer
Interventions: BIOLOGICAL: filgrastim|DRUG: cisplatin|DRUG: docetaxel|DRUG: fluorouracil|DRUG: paclitaxel|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rapid Antidepressant Effects of Ketamine in Major Depression
Status: COMPLETED
Conditions: Depression|Mood Disorders|Major Depresssion
Interventions: DRUG: Ketamine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Study to Assess the Efficacy and Safety of Viltolarsen in Ambulant Boys With DMD (RACER53)
Status: COMPLETED
Conditions: Duchenne Muscular Dystrophy
Interventions: DRUG: Viltolarsen|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Anti-CD33 Chimeric Antigen Receptor-Expressing T Cells (CD33CART) in Children and Young Adults With Relapsed/Refractory Acute Myeloid Leukemia
Status: RECRUITING
Conditions: Acute Myelogenous Leukemia
Interventions: BIOLOGICAL: CD33CART autologous|BIOLOGICAL: CD33CART allogeneic
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of the MovinCog Intervention in Children
Status: UNKNOWN
Conditions: Learning Disorders|Learning Disabilities|Cognitive Change
Interventions: BEHAVIORAL: Exercise|BEHAVIORAL: Cognitive|BEHAVIORAL: Active control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Kinesio Tape on Back Pain, Breastfeeding Success and Breastfeeding Self-Efficacy
Status: NOT_YET_RECRUITING
Conditions: Mothers Who Have Babies Between 0-6 Months and Are Actively Breastfeeding|Mothers Who Complain of Back Pain Due to Breastfeeding (Getting 6 Points or More on VAS in the Mothers' Own Evaluation)
Interventions: OTHER: Kinesio taping with angle and tension
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Phase III Study of BAY43-9006 in Patients With Advanced Hepatocellular Carcinoma (HCC) Treated After Transcatheter Arterial Chemoembolization (TACE)
Status: COMPLETED
Conditions: Carcinoma, Hepatocellular
Interventions: DRUG: Sorafenib (Nexavar, BAY43-9006)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety and Tolerability of CC-92328 in Participants With Relapsed and/or Refractory Multiple Myeloma
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: CC-92328
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Investigational Immuno-therapy Study of Nivolumab Given After Surgery in Non-Small Cell Lung Cancer (NSCLC) Participants With Minimal Residual Disease
Status: WITHDRAWN
Conditions: Non-Small Cell Lung Cancer|Non-Small-Cell Lung Carcinoma|Circulating Tumor DNA
Interventions: BIOLOGICAL: Nivolumab|DRUG: Vinorelbine|DRUG: Gemcitabine|DRUG: Docetaxel|DRUG: Pemetrexed|DRUG: Cisplatin|DRUG: Carboplatin|DRUG: Paclitaxel|OTHER: Observation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess Efficay and Safety of LC350189 Different Doses in Gout Patients With Hyperuricemia
Status: COMPLETED
Conditions: Gout|Hyperuricemia
Interventions: DRUG: LC350189 formulated capsule|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Efficacy of Regorafenib in Combination With FOLFIRINOX in Patients With Colorectal Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Colorectal Cancer
Interventions: COMBINATION_PRODUCT: Folfirinox + regorrafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study of the Effects of XOMA 052 on Insulin Production in Subjects With Well Controlled Type 1 Diabetes
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: DRUG: Xoma 052|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Improving Outcomes In Diabetic Patients During CABG Surgery By Optimizing Glycemic Control
Status: COMPLETED
Conditions: Glycemic Control
Interventions: DRUG: A IV Insulin drip|DRUG: B Low Dose GIK|DRUG: C High Dose GIK
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hemodynamic Efficiency of an Hemodialysis Treatment With High Permeability in Post-resuscitation Shock
Status: COMPLETED
Conditions: Cardiac Arrest|Sudden Cardiac Death|Shock
Interventions: DEVICE: hemodialysis with high permeability (HDHP)|PROCEDURE: CVVH
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Alternative Nicotine Delivery Systems as Potential Harm Reduction Tools for Persistent Cigarette Smokers
Status: NOT_YET_RECRUITING
Conditions: E-cigarette Use|Cigarette Smoking|Harm Reduction|Tobacco Use
Interventions: OTHER: E-cigarettes|OTHER: Oral nicotine pouches
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Randomized Trial Comparing Oxytocin and Oxytocin + Ergometrine for Prevention of Postpartum Haemorrhage at Caesarean Section
Status: COMPLETED
Conditions: Prevention of Post Partum Haemorrhage
Interventions: DRUG: Oxytocin|DRUG: Oxytocin ergometrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Phase I Study of CUDC-101 With Cisplatin and Radiation in Subjects With Head & Neck Cancer
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: DRUG: CUDC-101|DRUG: Cisplatin|RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Systemic and Local Levels of Lidocaine During Surgery for the Removal of Glioblastoma
Status: COMPLETED
Conditions: Glioblastoma
Interventions: PROCEDURE: Biospecimen Collection|DRUG: Lidocaine|PROCEDURE: Resection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Nitric Oxide in Cardiac Surgery Patients With Endothelial Dysfunction.
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Kidney Injury
Interventions: DRUG: Nitric Oxide|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Improving Parental Psychosocial Functioning and Early Developmental Outcomes in Children With Sickle Cell Disease
Status: COMPLETED
Conditions: Sickle Cell Disease|Cognitive Ability, General|Psychological Stress|Parenting
Interventions: BEHAVIORAL: Play therapy|OTHER: Problem solving skills
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Carotid Artery Intima Media Thickness Can Predict the Response to Phosphodiesterase 5 Inhibitors in the Patients With Moderate Erectile Dysfunction
Status: COMPLETED
Conditions: Erectile Dysfunction Due to Arterial Disease
Interventions: DIAGNOSTIC_TEST: CIMT (Carotid artery intima media thickness measurement)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase 2a Study of TAS5315 in Patients With Chronic Spontaneous Urticaria
Status: COMPLETED
Conditions: Chronic Spontaneous Urticaria
Interventions: DRUG: TAS5315 Dose 1|DRUG: TAS5315 Dose 2|DRUG: TAS5315 Dose 3|DRUG: TAS5315 Dose 4|DRUG: TAS5315 Dose 5|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Effect of Cromolyn Sodium in Uremic Pruritus
Status: COMPLETED
Conditions: End Stage Renal Disease|Pruritus
Interventions: DRUG: cromolyn sodium|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Negative Pressure Wound Therapy vs. Conventional Dressings for Prevention of Wound Complications After Revision THA
Status: ACTIVE_NOT_RECRUITING
Conditions: Infection, Drainage
Interventions: DEVICE: Negative Pressure Wound Therapy (NPWT)|DEVICE: Sterile Antimicrobial Dressings
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION