pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Randomized Trial of COVID-19 Booster Vaccinations (Cobovax Study)
Status: ACTIVE_NOT_RECRUITING
Conditions: COVID-19 Vaccination
Interventions: BIOLOGICAL: BNT162b2|BIOLOGICAL: CoronaVac
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Role of Alprazolam in the Management of Acute Coronary Syndrome
Status: UNKNOWN
Conditions: Acute Coronary Syndrome|Myocardial Infarction|ST Elevation Myocardial Infarction|Heart Diseases|Anxiety
Interventions: DRUG: Alprazolam|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Residual Pockets in Periodontal Patients Using an Oscillating Chitosan Device
Status: COMPLETED
Conditions: Periodontitis
Interventions: DEVICE: chitosan brush|DEVICE: ultrasonic scaler
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Single- and Multiple-Dose Study of the Pharmacokinetics of TAK-491 in Healthy Chinese Participants
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: TAK-491|DRUG: TAK-491 placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Skip Prep of Vaginal Delivery to Prevent Puerperal / Perinatal Infection in Vaginal Delivery
Status: NOT_YET_RECRUITING
Conditions: Vaginal Delivery|Surgical Site Infection
Interventions: DRUG: Povidone-Iodine|DRUG: Chlorhexidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Dementia Antipsychotics And Antidepressants Discontinuation Study
Status: COMPLETED
Conditions: Dementia
Interventions: DRUG: Risperidone|DRUG: Escitalopram|DRUG: Citalopram|DRUG: Sertraline|DRUG: Paroxetine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Addition of Cisatracurium to Lidocaine VS Plain Lidocaine
Status: COMPLETED
Conditions: Anesthesia
Interventions: DRUG: Cisatracurium Besylate|DRUG: Lignocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Quality of Life Impact After Enhanced Follow-up of Ostomy Patients
Status: UNKNOWN
Conditions: Stoma Ileostomy|Stoma Colostomy|Quality of Life
Interventions: OTHER: stoma follow-up|OTHER: standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Removal of Nasogastric Feeding Tube Post Extubation in ICU : a Prospective Randomized Trial
Status: RECRUITING
Conditions: Deglutition Disorders|Intensive Care Unit Syndrome|Swallowing Disorder|Feeding or Eating Disorder
Interventions: PROCEDURE: Nasogastric Tube removal during extubation|DIAGNOSTIC_TEST: Yale Swallow Protocol|PROCEDURE: Classif Nasogastric Tube Management|DIAGNOSTIC_TEST: Classic swallowing test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SPD503 in Subjects Aged 6-17 Years With Generalized Anxiety Disorder (GAD), Separation Anxiety Disorder (SAD), or Social Phobia (SoP)
Status: COMPLETED
Conditions: Generalized Anxiety Disorder (GAD)|Anxiety, Separation|Phobia, Social
Interventions: DRUG: SPD503 (extended-release Guanfacine hydrochloride)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Caring for the Whole Person
Status: UNKNOWN
Conditions: Behavioral Health
Interventions: OTHER: Access to Care|OTHER: Depression Screening|OTHER: Patient-Provider Relationship|OTHER: Patient-Clinic Interactions|OTHER: Stigma|OTHER: Provider Continuity|OTHER: Symptom Severity|OTHER: Diagnoses|OTHER: Social support|OTHER: Preventive Screening|OTHER: Inpatient Hospitalization Utilization|OTHER: Inpatient Readmissions|OTHER: Post-Admission follow-up
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: : Protescal: Prevention of Hypertrophic Scar and Keloid Formation Post Caesarean Section
Status: COMPLETED
Conditions: Caesarean Wound|Hypertrophic Surgical Scar|Keloid Scar Following Surgery
Interventions: DRUG: Protescal gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of RC28-E Injection in Wet Age-related Macular Degeneration
Status: COMPLETED
Conditions: Wet Age-Related Macular Degeneration
Interventions: BIOLOGICAL: intravitreal injection of RC28-E 0.5mg|BIOLOGICAL: intravitreal injection of RC28-E 1.0mg|BIOLOGICAL: intravitreal injection of RC28-E2.0mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination of PCI-32765 With Obinutuzumab in Untreated Follicular Lymphoma
Status: UNKNOWN
Conditions: Indolent Non-Hodgkin Lymphoma
Interventions: DRUG: Ibrutinib|DRUG: GA 101
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Lasmiditan in Healthy Participants When Co-administered With Topiramate
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Lasmiditan|DRUG: Placebo|DRUG: Topiramate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Assessment of the Safety, Tolerability, and Pharmacokinetic of HM201
Status: COMPLETED
Conditions: Ulcerative Colitis|Crohn's Disease
Interventions: DRUG: HM201|DRUG: Placebo|DRUG: HM201|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A 4-week, Randomized, Rater-blinded, Parallel Study to Evaluate Quetiapine in Improving Sleep Quality of Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: quetiapine fumarate|DRUG: haloperidol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MAXimizing Flow Diversion Effect On the Treatment of Large Intracranial Aneurysms With Embolization Devices
Status: UNKNOWN
Conditions: Intracranial Aneurysm
Interventions: PROCEDURE: Neurovascular treatment of intracranial aneurysms|DEVICE: AneurysmFlow image processing software
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Saxagliptin's Effects on Microalbuminuria Improvement in Type 2 Diabetic Patients
Status: UNKNOWN
Conditions: Microalbuminuria|Microalbuminuria /Creatinine Ratios ACR
Interventions: DRUG: Saxagliptin|DRUG: glimepiride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Home Monitoring of Diabetic Macular Edema
Status: RECRUITING
Conditions: Macular Edema Due to Diabetes Mellitus
Interventions: DEVICE: Home OCT monitoring model|DEVICE: Hospital-based monitoring with a staff-administrated OCT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Single Dose of Tranexamic Acid and Blood Loss, in Elderly Patients With Hip Fracture
Status: UNKNOWN
Conditions: Blood Loss, Surgical|Hip Fractures|Complication, Postoperative
Interventions: DRUG: Tranexamic Acid 15mg/kg , iv, Single Dose|DRUG: Normal Saline, 100mg, iv, Singe dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of Ciprofol Compared to Propofol for Nonintubated General Anesthesia in Patients Undergoing TAVR
Status: UNKNOWN
Conditions: Anesthesia, General
Interventions: DRUG: Ciprofol|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Afferent Neurocardiac Signals, Cue Reactivity, and Cognitive Control
Status: UNKNOWN
Conditions: Binge Drinking
Interventions: BEHAVIORAL: Resonance breathing|BEHAVIORAL: Low demand cognitive task
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety, Tolerability and Efficacy of Evolocumab (AMG 145) in Children With Inherited Elevated Low-density Lipoprotein Cholesterol (Familial Hypercholesterolemia)
Status: COMPLETED
Conditions: Familial Hypercholesterolemia
Interventions: BIOLOGICAL: Evolocumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Using Informatics to Enhance Care of Older Emergency Department Patients
Status: COMPLETED
Conditions: Elderly; Renal Insufficiency
Interventions: PROCEDURE: Computer-Assisted Decision Support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A New Pathway With BronchOscopic or Oesophageal Ultrasound for Lung Cancer Diagnosis and STaging (BOOST)
Status: COMPLETED
Conditions: Bronchogenic Carcinoma
Interventions: PROCEDURE: Endobronchial or Endoscopic Ultrasound|PROCEDURE: Bronchoscopy, CT-guided biopsy, PET scan, Mediastinoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Remote Ischemic Preconditioning on Incidence of Atrial Fibrillation in Patients Undergoing Coronary Artery Bypass Graft Surgery
Status: UNKNOWN
Conditions: Atrial Fibrillation
Interventions: OTHER: sphygmomanometer cuff inflations|OTHER: standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Combined Cumulative Irritation Potential and Repeat Insult Patch Test of LEO 90100
Status: COMPLETED
Conditions: Psoriasis Vulgaris
Interventions: DRUG: LEO 90100|DRUG: Vehicle|DRUG: Petrolatum ointment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: ZOSTAVAX® in Renal Transplant Patients
Status: COMPLETED
Conditions: Herpes Zoster
Interventions: BIOLOGICAL: Live attenuated herpes zoster vaccine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: PGL4001 Efficacy Assessment in Reduction of Symptoms Due to Uterine Leiomyomata (PEARLIII-extension Study)
Status: COMPLETED
Conditions: Uterine Fibroids
Interventions: DRUG: PGL4001, placebo, drug free period|DRUG: PGL4001, progestin, drug free period
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Complete microscopicE Resection Margin (R0) and Lymph Node Involvement After Standard Pancreatosplenectomy (SPS) Versus Radical Anterograde Modular Pancreatosplenectomy
Status: RECRUITING
Conditions: Pancreatic Cancer
Interventions: PROCEDURE: pancreatosplenectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Closed-Loop Deep Brain Stimulation for Major Depression
Status: RECRUITING
Conditions: Major Depressive Disorder
Interventions: DEVICE: Stimulation-ON|DEVICE: Stimulation-OFF|DEVICE: Stimulation-ON Active Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SWITCH Diets Study: Self-monitoring With Internet Technology to Choose Healthy Diets
Status: RECRUITING
Conditions: Overweight and Obesity|Pre-diabetes
Interventions: BEHAVIORAL: learning modules (within app)|BEHAVIORAL: SWITCH app (self-regulation features) - Experimental|BEHAVIORAL: SWITCH app (self-regulation features) - Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Diagnostic Performance Evaluation of a Novel SARS-CoV-2 (COVID-19) Antigen Detection Test
Status: COMPLETED
Conditions: Covid19|SARS-CoV-2 Infection
Interventions: DIAGNOSTIC_TEST: RT-qPCR test|DIAGNOSTIC_TEST: COVID-VIRO® test
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Pilot Study of the Utility of Empiric Antibiotic Therapy for Suspected ICU-Acquired Infection
Status: COMPLETED
Conditions: Nosocomial Infection|Pneumonia|Systemic Inflammatory Response Syndrome|Critical Illness|Pyrexia
Interventions: DRUG: Site-specific empiric regimens included: Meropenem|DRUG: Piperacillin/tazobactam|DRUG: Ciprofloxacin and cefazolin +/- metronidazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study to Determine the Safety and Efficacy of Second-line Treatment With Metformin and Chemotherapy (FOLFOX6 or FOFIRI) in the Second Line Threatment of Advanced Colorectal Cancer
Status: TERMINATED
Conditions: Previously Treated Advanced Colorectal Cancer
Interventions: DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Scapular Proprioceptive Neuromuscular Facilitation (PNF) Exercises
Status: COMPLETED
Conditions: Postural Kyphosis
Interventions: OTHER: PNF EXERCISES|OTHER: strength exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fentanyl and Crushed Ticagrelor in Percutaneous Coronary Intervention
Status: RECRUITING
Conditions: Percutaneous Coronary Intervention
Interventions: DRUG: Fentanyl|DRUG: Ticagrelor 90Mg Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Controlled-Release Morphine for Chronic Neuropathic Pain After Spinal Cord Injury
Status: COMPLETED
Conditions: Neuropathic Pain|Spinal Cord Injury
Interventions: DRUG: Modified-release morphine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Anterior Cruciate Ligament Reconstruction Made With Hamstring Tendon And Quadriceps Tendon Autografts
Status: COMPLETED
Conditions: Anterior Cruciate Ligament Injuries
Interventions: PROCEDURE: anterior cruciate ligament recontruction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: DORADO - Fixed Doses of Darusentan as Compared to Placebo in Resistant Hypertension
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Darusentan|DRUG: Darusentan Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study the Effect of Upper Expansion Appliances on Lower Jaw Forward Projection/Growth
Status: UNKNOWN
Conditions: Overbite (Excessive) Horizontal
Interventions: DEVICE: Upper arch Wilson quadhelex appliance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Amnion Bilayer and Stem Cell Combination Therapy on Thin Endometrium Infertile Patients
Status: UNKNOWN
Conditions: Cell- and Tissue-Based Therapy
Interventions: BIOLOGICAL: Amnion only|BIOLOGICAL: Amnion - endometrium cells|BIOLOGICAL: Amnion - amnion epithelial cells|BIOLOGICAL: Amnion-EnSC-AESC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Safety Study of Gene Modified Donor T-cells Following TCRαβ+ Depleted Stem Cell Transplant
Status: TERMINATED
Conditions: Acute Lymphoblastic Leukemia|Leukemia, Acute Myeloid (AML), Child|Lymphoma, Non-Hodgkin|Myelodysplastic Syndrome|Primary Immunodeficiency|Anemia, Aplastic|Osteopetrosis|Hemoglobinopathies|Cytopenia|Fanconi Anemia|Diamond Blackfan Anemia|Thalassemia|Anemia, Sickle Cell
Interventions: BIOLOGICAL: BPX-501 T cells|DRUG: Rimiducid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of EXC 001 to Improve the Appearance of Scars From Prior Breast Surgery
Status: COMPLETED
Conditions: Reduction in Hypertrophic Skin Scarring
Interventions: DRUG: EXC 001|DRUG: EXC 001|DRUG: EXC 001|DRUG: EXC 001
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess Efficacy and Safety of CDR132L in Patients With Reduced Left Ventricular Ejection Fraction After Myocardial Infarction
Status: ACTIVE_NOT_RECRUITING
Conditions: Myocardial Infarction, Acute|Heart Failure, Left Sided
Interventions: DRUG: CDR132L|DRUG: Placebo to CDR132L
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of AOC 1001 in Adult Myotonic Dystrophy Type 1 (DM1) Patients
Status: COMPLETED
Conditions: DM1|Myotonic Dystrophy 1|Myotonic Dystrophy|Myotonic Dystrophy Type 1 (DM1)|Dystrophy Myotonic|Myotonic Disorders|Steinert Disease|Myotonic Muscular Dystrophy
Interventions: DRUG: AOC 1001|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Survival of Hybrid Laminate Veneers Using Two Different Tooth Preparation Techniques:Randomized Clinical Trial
Status: COMPLETED
Conditions: Discoloration, Tooth|Malformed Tooth|Diastema
Interventions: PROCEDURE: traditional technique of tooth preparation|PROCEDURE: aesthetic preevaluative temporary technique for tooth preparation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bariatric Atrial Restoration of Sinus Rhythm
Status: TERMINATED
Conditions: Atrial Fibrillation|Morbid Obesity
Interventions: PROCEDURE: Bariatric surgery|PROCEDURE: Atrial Fibrillation (AF) Catheter Ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Evaluation of Serum Testosterone Concentrations After Administration of Clomiphene Citrate
Status: RECRUITING
Conditions: Testosterone Deficiency
Interventions: DRUG: Clomiphene Citrate 25mg|DRUG: Clomiphene Citrate 50mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Interest of Adapted Physical Activity by Tele-rehabilitation in Chronic Pathology - Idiopathic Scoliosis in Adolescents
Status: RECRUITING
Conditions: Adolescent Idiopathic Scoliosis
Interventions: OTHER: Home-based adapted physical activity program supervised by an APA teacher via individual video conference.|OTHER: First period of the home-based adapted physical activity program with an exercise booklet.|OTHER: Second period of the home-based adapted physical activity program with an exercise booklet.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessing E-Cigarettes for Tobacco Harm Reduction in the Context of Lung Cancer Screening
Status: NOT_YET_RECRUITING
Conditions: Electronic Cigarette Use|Smoking, Cigarette|Nicotine Dependence
Interventions: OTHER: NJOY ACE e-cigarette
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Self or Clinic Administration of DepoProvera
Status: COMPLETED
Conditions: Contraception
Interventions: DRUG: Medroxyprogesterone 17-Acetate|DRUG: Medroxyprogesterone 17-Acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Treating Chronic Pain in Buprenorphine Patients in Primary Care Settings
Status: ACTIVE_NOT_RECRUITING
Conditions: Opioid-Related Disorders
Interventions: BEHAVIORAL: Treating Opioid Patients' Pain and Sadness (TOPPS)|BEHAVIORAL: Health Education (HE)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Early Cancer Biomarkers in Breath Condensate in Population of Individuals With High-Risk of Lung Cancer Undergoing LDCT Screening.
Status: RECRUITING
Conditions: Lung Cancer
Interventions: DIAGNOSTIC_TEST: Exhaled breath condensate sampling|DIAGNOSTIC_TEST: Blood sampling|PROCEDURE: LDCT|DIAGNOSTIC_TEST: Vital signs|DIAGNOSTIC_TEST: Spirometry
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Study to Compare Maternal, Fetal, and Infant Outcomes of Women With Mild to Moderate Atopic Dermatitis Exposed to Ruxolitinib Cream During Pregnancy With an Unexposed Control Population
Status: RECRUITING
Conditions: Pregnancy Related|Atopic Dermatitis
Interventions: DRUG: Ruxolitinib Cream
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Role of the Toxic Metal Cadmium in the Mechanism Producing Infertility With a Varicocele
Status: COMPLETED
Conditions: Varicocele|Male Infertility|Hypospermatogenesis|Non-Obstructive Azoospermia
Interventions: PROCEDURE: Varicocele repair
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Passive Leg Raising Attenuates and Delays Tourniquet Deflation-induced Hypotension and Tachycardia
Status: COMPLETED
Conditions: Hypotension|Tachycardia
Interventions: PROCEDURE: passive leg raising
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Middle Lobe Only Laser Vaporization or Total Prostate Vaporization of the Prostate, Prospective Cohort Study
Status: NOT_YET_RECRUITING
Conditions: Benign Prostatic Hyperplasia
Interventions: PROCEDURE: Middle lobe only Photoselective vaporization of the prostate (PVP)|PROCEDURE: Complete PVP
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: XIAP Antisense AEG35156 in Combination With Sorafenib in Patients With Advanced Hepatocellular Carcinoma (HCC)
Status: COMPLETED
Conditions: Advanced Hepatocellular Carcinoma
Interventions: DRUG: AEG35156 antisense IV infusion|DRUG: Sorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Outcomes Following Combined Adductoplasty™ and Lapiplasty® (MTA3D)
Status: RECRUITING
Conditions: Metatarsus Adductus|Hallux Valgus
Interventions: DEVICE: Treatment of metatarsus adductus and hallux valgus with the Adductoplasty™ Procedure in combination with the Lapiplasty® Procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study To Evaluate The Safety, Tolerability, And Pharmacokinetics Of Oral Pf-06650833 In Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: PF-06650833|DRUG: Placebo|DRUG: PF-06650833|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Lung Ultrasound to Diagnose the Etiology of Respiratory Failure in a PICU.
Status: COMPLETED
Conditions: Pediatric Respiratory Diseases|Respiratory Failure
Interventions: DIAGNOSTIC_TEST: Lung ultrasound|DIAGNOSTIC_TEST: Clinical exam|DIAGNOSTIC_TEST: Chest x-ray
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Randomized Study Comparing Pre- and Postoperative vs. Conventional Adjuvant Treatment in Receptor-negative Patients
Status: COMPLETED
Conditions: Early Stage Breast Cancer
Interventions: DRUG: Cyclophosphamide|DRUG: Methotrexate|DRUG: Fluorouracil|DRUG: Epirubicin|OTHER: Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: O6-Benzylguanine-Mediated Tumor Sensitization With Chemoprotected Autologous Stem Cell in Treating Patients With Malignant Gliomas
Status: TERMINATED
Conditions: Glioblastoma|Gliosarcoma
Interventions: RADIATION: 3-Dimensional Conformal Radiation Therapy|PROCEDURE: Autologous Hematopoietic Stem Cell Transplantation|DRUG: Carmustine|BIOLOGICAL: Filgrastim|PROCEDURE: In Vitro-Treated Peripheral Blood Stem Cell Transplantation|RADIATION: Intensity-Modulated Radiation Therapy|OTHER: Laboratory Biomarker Analysis|DRUG: O6-Benzylguanine|DRUG: Plerixafor|RADIATION: Proton Beam Radiation Therapy|DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of a Novel Investigational Drug in Rheumatoid Arthritis Patients (MK-0873-012)(COMPLETED)
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: MK-0873|DRUG: Comparator: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prolonged Pulsatile Kisspeptin Administration in Hypogonadotropic Hypogonadism
Status: RECRUITING
Conditions: Hypogonadotropic Hypogonadism
Interventions: DRUG: kisspeptin 112-121|DRUG: GnRH
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigation on Safety, Tolerability, and Pharmacokinetics of Single Doses of NNC0113-0987 in Healthy Male Subjects
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2|Healthy
Interventions: DRUG: NNC0113-0987|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial of an Integrated E-diagnosis Assessment to Improve the Management of Childhood Illnesses in Burkina Faso
Status: COMPLETED
Conditions: IMCI Guidelines|Childhood Illnesses
Interventions: OTHER: integrated ediagnostic approach (IeDA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Bupropion and Counseling With or Without Contingency Management to Enhance Smoking Cessation in Treating Cancer Survivors Who Continue to Smoke
Status: COMPLETED
Conditions: Cancer Survivor|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: BEHAVIORAL: smoking cessation intervention|DRUG: bupropion hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: PREVENTION
Clinical trial: Improvement of Local Control in Skull Base, Spine and Sacral Chordomas Treated by Surgery and Protontherapy Targeting Hypoxic Cells Revealed by [18F]FAZA) PET/CT Tracers
Status: ACTIVE_NOT_RECRUITING
Conditions: Skull Base Chordoma|Vertebral Chordoma
Interventions: PROCEDURE: Surgery|RADIATION: Protontherapy|DRUG: 18F FAZA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Maintenance Chemotherapy After Neoadjuvant Chemoradiation Therapy for Distal Rectal Cancer
Status: TERMINATED
Conditions: Rectal Neoplasms
Interventions: DRUG: 5FU/Leucovorin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Clinical and Microbial Efficacy and Safety of AzaSite Compared to Tobramycin for Bacterial Conjunctivitis (C-01-401-004)
Status: COMPLETED
Conditions: Bacterial Conjunctivitis
Interventions: DRUG: AzaSite|DRUG: Tobramycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Insulin-Only Bionic Pancreas Bridging Study- Pediatric Transitional Study
Status: COMPLETED
Conditions: Type1 Diabetes Mellitus
Interventions: DEVICE: iLet Bionic Pancreas insulin-only configuration with Humalog or Novolog|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Newly Developed PreCore Needle With Conventional Fine Needle in Suspected Unresectable Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DEVICE: 22 gauge ProCore needle aspiration|DEVICE: 22 gauge Fine needle aspiration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Objective Characterizatoion of Repetitive Behaviors
Status: RECRUITING
Conditions: OCD|Tic Disorders|Gilles de la Tourette Syndrome
Interventions: DEVICE: EEG|DEVICE: MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of Automated Oxygen Control With and Without Automated Pressure Control in Preterm Ventilated Infants.
Status: COMPLETED
Conditions: Oxygen Saturation Targetting in Preterm Ventilated Infants
Interventions: OTHER: Mode of ventilation (Volume Guarantee)®|OTHER: Mode of ventilation (Volume control Ventilation)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Single-dose and Multiple-dose Study to Evaluate the Pharmacokinetics and Pharmacodynamics of DBPR108 Tablets in Type 2 Diabetes Mellitus Patients
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: DBPR108 tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A First-In-Human Study to Evaluate Safety, Tolerability, Reactogenicity, and Immunogenicity of JNJ-64300535, a DNA Vaccine, Administered by Electroporation-Mediated Intramuscular Injection, in Participants With Chronic Hepatitis B Who Are on Stable Nucleos(t)Ide Therapy and Virologically Suppressed
Status: COMPLETED
Conditions: Hepatitis B, Chronic
Interventions: BIOLOGICAL: JNJ-64300535|BIOLOGICAL: Placebo|DRUG: Nucleos(t)ide Analogs (NA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Standard Dose Bevacizumab Versus Low Dose Bevacizumab Plus Lomustine (CCNU) for Recurrent Glioblastoma Multiforme (GBM)
Status: COMPLETED
Conditions: Brain Cancer|Glioblastoma
Interventions: DRUG: Standard Dose Bevacizumab|DRUG: Low Dose Bevacizumab|DRUG: Lomustine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Laparoscopic Single-Anastomosis Duodenal-Jejunal Bypass With Sleeve Gastrectomy vs Laparoscopic Duodenal Switch
Status: NOT_YET_RECRUITING
Conditions: Obesity
Interventions: PROCEDURE: Duodenal Switch|PROCEDURE: Duodenal-ileal Bypass with Sleeve Gastrectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Pulmonary Embolism International THrOmbolysis Study-3
Status: RECRUITING
Conditions: Pulmonary Embolism
Interventions: DRUG: Alteplase|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: ACY-1215 in Combination With BCR Pathway Inhibitors in Relapsed CLL
Status: ACTIVE_NOT_RECRUITING
Conditions: Recurrent Chronic Lymphoid Leukemia
Interventions: DRUG: ACY-1215|DRUG: Ibrutinib|DRUG: Idelalisib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study For Patients With Untreated Gastric Cancer Who Will Receive Capecitabine And Lapatinib
Status: COMPLETED
Conditions: Neoplasms, Gastrointestinal Tract
Interventions: DRUG: Lapatinib and Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Belatacept as a Replacement for CNIs 3 to 12 Months Post-transplantation in Patients With Early Graft Dysfunction
Status: RECRUITING
Conditions: Chronic Kidney Failure
Interventions: DRUG: Belatacept 250 Milligram Intravenous Powder for Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Geriatric Communication Skills Training Program for Oncology Clinicians
Status: COMPLETED
Conditions: GI Cancer|Lymphoma|GU Cancer|Bone Marrow Transplant
Interventions: BEHAVIORAL: Self-Efficacy Assessment|BEHAVIORAL: UCLA Geriatrics Attitudes Scale|BEHAVIORAL: Course Evaluations|BEHAVIORAL: The Consultation and Relational Empathy (CARE) questionnaire|BEHAVIORAL: Consumer Assessment of Health Care Providers and Systems Program (CAHPS)|BEHAVIORAL: Patient activation measure (PAM) scale
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study Evaluating TSE-424/Placebo/Raloxifene in Preventing Osteoporosis in Postmenopausal Women
Status: COMPLETED
Conditions: Osteoporosis
Interventions: DRUG: Bazedoxifene Acetate (TSE-424)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Ultrasonographic Evaluation of Osteopathic Manipulation for Thoracic Outlet Syndrome
Status: COMPLETED
Conditions: Thoracic Outlet Syndrome
Interventions: OTHER: Osteopathic Manipulative Treatment (OMT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of tDCS in the Treatment of Resistant Auditory Hallucinations in Schizophrenia
Status: RECRUITING
Conditions: Schizophrenia|Hallucinations|Refractory Schizophrenia
Interventions: DEVICE: transcranial direct current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial to Compare Efficacy and Tolerability of Faslodex With Arimidex in Patients With Advanced Breast Cancer
Status: COMPLETED
Conditions: Metastatic Breast Cancer
Interventions: DRUG: fulvestrant|DRUG: anastrozole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Tolerance and Equivalence of hCG-IBSA vs Recombinant Human Chorionic Gonadotrophin in Women Undergoing In Vitro Fertilisation
Status: COMPLETED
Conditions: Infertility
Interventions: DRUG: hCG-IBSA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Adding Alisporivir (DEB025) to Peginterferon (IFN) Alfa-2a (Peg-IFN Alfa-2a) and Ribavirin in Chronic HCV Genotype 1 Patients Who Relapsed or Did Not Respond to Previous Treatment
Status: COMPLETED
Conditions: Hepatitis C
Interventions: DRUG: Alisporivir|DRUG: Peginterferon alfa-2a|DRUG: Ribavirin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Explore the Effect of Vitex Negundo and Zingiber Officinale on Non-specific Chronic Low Back Pain Due to Sedentary Lifestyle
Status: COMPLETED
Conditions: Low Back Pain
Interventions: OTHER: Vitex negundo + Zingiber officinale|OTHER: Placebo (MCC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Comparison of MgSO4 Versus Meperidine for Prevention of Shivering During Spinal Anesthesia
Status: COMPLETED
Conditions: Shivering
Interventions: DRUG: Magnesium sulfate|DRUG: Meperidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Safety and Efficacy Study of the Hepatitis E Vaccine in Nepal.
Status: COMPLETED
Conditions: Hepatitis
Interventions: BIOLOGICAL: Hepatitis E vaccine, recombinant (Sar 56 kDa)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A 8-month Study on the Use of Intra-oral Camera and Text Messages on Gingivitis Control
Status: COMPLETED
Conditions: Behavior and Behavior Mechanisms|Gingivitis
Interventions: DEVICE: Mobile Text Messages|DEVICE: Intra Oral Camera
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Phase II Study of Neoadjuvant XELOX + Lapatinib in HER2(+) Gastric Cancer Patients With Liver Metastasis
Status: COMPLETED
Conditions: HER2-positive Gastric Cancer Patients With Liver Metastasis
Interventions: DRUG: Lapatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Melatonin Supplementation to Improve Sleep in Patients With Heart Failure
Status: WITHDRAWN
Conditions: Heart Failure|Sleep Disorders
Interventions: DRUG: melatonin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Therapy Dogs on Child Biology and Behavior
Status: COMPLETED
Conditions: Stress Reaction|Behavior, Social
Interventions: BEHAVIORAL: Therapy Dog|BEHAVIORAL: Stuffed Toy Dog|BEHAVIORAL: 5 Minute Puppy Video
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Exceptional Experiences (EE), Salience & Dopaminergic Neurotransmission
Status: COMPLETED
Conditions: Healthy|Schizotypal Personality
Interventions: DRUG: 200 mg levodopa/50 mg benserazide|DRUG: Dextrose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Lung Health Study II
Status: COMPLETED
Conditions: Lung Diseases|Lung Diseases, Obstructive|Chronic Obstructive Pulmonary Disease
Interventions: DRUG: triamcinolone|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized, Double-Blind, Placebo-Controlled Study of Oral Milk Immunotherapy for Cow's Milk Allergy
Status: COMPLETED
Conditions: Milk Hypersensitivity
Interventions: DRUG: cow's milk powder|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Safety and Therapeutic Effects of Transplantation of MNV-201 in Pediatric Patients With Pearson Syndrome
Status: RECRUITING
Conditions: Mitochondrial Diseases|Pearson Syndrome
Interventions: BIOLOGICAL: MNV-201
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Healthy Lunch and Snack Meal on Reaction Time and Well-being of Physicians and Nursing Staff (Go-No-Go)
Status: COMPLETED
Conditions: Nutrition Intervention
Interventions: OTHER: Dietary treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Safety and Immunogenicity of Fluzone® Quadrivalent and Fluzone® High-Dose, Influenza Vaccines, 2016-2017 Formulations
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Fluzone Quadrivalent vaccine, 2016-2017 formulation, No Preservative|BIOLOGICAL: Fluzone Quadrivalent vaccine, 2016-2017 formulation, No Preservative|BIOLOGICAL: Fluzone High-Dose, vaccine, 2016-2017 formulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Impact of a Multidimensional Intervention in Elderly Patients With Pneumonia
Status: COMPLETED
Conditions: Community-acquired Pneumonia|Healthcare-associated Pneumonia
Interventions: OTHER: Multidimensional intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of ZEN003694 in Patients With Metastatic Castration-Resistant Prostate Cancer
Status: COMPLETED
Conditions: Metastatic Castration-Resistant Prostate Cancer
Interventions: DRUG: ZEN003694
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tinzaparin Lead-In to Prevent the Post-Thrombotic Syndrome
Status: TERMINATED
Conditions: Deep Vein Thrombosis|Post Thrombotic Syndrome
Interventions: DRUG: tinzaparin|DRUG: Rivaroxaban
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: tDCS and Robotic Training in Adults With Cerebral Palsy
Status: ACTIVE_NOT_RECRUITING
Conditions: Cerebral Palsy|Hemiplegia
Interventions: BEHAVIORAL: Upper Extremity Robotics, tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Impact of Rhinoplasty Approach and Used Autologous Cartilage Grafts on the Nasal Skin-soft Tissue Envelope Metabolism
Status: NOT_YET_RECRUITING
Conditions: Rhinoplasty|Nasal Skin-soft Tissue Envelope Metabolism|Lactic Acid|Autologous Cartilage Grafting
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase I Study to Investigate Tolerability and Efficacy of ALECSAT Administered to Glioblastoma Multiforme Patients
Status: COMPLETED
Conditions: Glioblastoma Multiforme
Interventions: BIOLOGICAL: ALECSAT cell based immunotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non-invasive Imaging of GI Inflammation Using Microbubble Contrast Enhanced Ultrasonography
Status: TERMINATED
Conditions: Inflammatory Bowel Disease
Interventions: OTHER: Definity|OTHER: Definity
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Multi-Detector Spiral Computed Tomography Alone Versus Combined Strategy With Lower Limb Compression Ultrasonography in Outpatients Suspected of Pulmonary Embolism
Status: COMPLETED
Conditions: Pulmonary Embolism
Interventions: PROCEDURE: multi-detector helical computed tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose:
Clinical trial: Intravenous Esketamine on Prevention of Postoperative Depression in Patients Undergoing Cardiac Surgery
Status: UNKNOWN
Conditions: Postoperative Depression
Interventions: DRUG: Esketamine|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: RCT of Implantable Defibrillators in Patients With Non Ischemic Cardiomyopathy, Scar and Severe Systolic Heart Failure
Status: RECRUITING
Conditions: Heart Failure
Interventions: DEVICE: Implantable Cardioverter-Defibrillator (ICD) or Cardiac Resynchronisation Therapy Defibrillator (CRTD)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety of CB-280 in Patients With Cystic Fibrosis
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: CB-280|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT