pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Intracorporeal Versus Extracorporeal Morcellation: Clinical Efficacy and Safety Outcomes
Status: COMPLETED
Conditions: Uterine Myoma
Interventions: PROCEDURE: Extracorporeal morcellation|PROCEDURE: Intracorporeal morcellation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to Assess Molecular Changes in Adult Participants With Moderate to Severe Hidradenitis Suppurativa or With Moderate to Severe Atopic Dermatitis Receiving Subcutaneous Injections of Lutikizumab
Status: RECRUITING
Conditions: Hidradenitis Suppurativa|Atopic Dermatitis
Interventions: DRUG: Lutikizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of iTBS Combined With NMES on Dysphagia After Stroke
Status: NOT_YET_RECRUITING
Conditions: Stroke|Dysphagia|Intermittent Theta Burst Stimulation|Neuromuscular Electrical Stimulation|Functional Near-infrared Spectroscopy
Interventions: DEVICE: Transcranial magnetic stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility Study on Implementing Consultation-based High-quality Palliative Care Services in Intensive Care Units
Status: RECRUITING
Conditions: Critical Illness
Interventions: BEHAVIORAL: High-quality palliative care through consultation-based palliative care services in the ICU
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Remote Ischaemic Conditioning and Coronary Endothelial Function (RIC-COR)
Status: COMPLETED
Conditions: Ischemic Preconditioning|Coronary Disease
Interventions: PROCEDURE: Remote ischaemic conditioning|PROCEDURE: Arm cuff placement, no inflation;
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Corticotropin Stimulation in Adrenal Venous Sampling for Patients With Primary Aldosteronism(ADOPA)
Status: COMPLETED
Conditions: Primary Aldosteronism
Interventions: DRUG: Adrenocorticotropic hormone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparison of Cefdinir and Cefdinir/Clavulanic Acid Combination in Adults
Status: UNKNOWN
Conditions: Acute Exacerbation of Chronic Bronchitis|Community-Acquired Pneumoniae
Interventions: COMBINATION_PRODUCT: Cefdinir/clavulanic acide 300/125 mg film-coated tablets|DRUG: Cefdinir 300Mg Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Electrically Evoked Compound Action Potentials Human Observation Medtronic Algorithm Comparison Study
Status: COMPLETED
Conditions: Chronic Pain
Interventions: DEVICE: Open-loop testing, Closed-loop testing - External Spinal Cord Stimulator (SCS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Influence of Dietary Omega-3 Fatty Acids in Various triOMEG Sausages on the HS-Omega-3 Index in Healthy Individuals
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: OTHER: Sausage: Triomeg|OTHER: Sausage: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Pulpotomy in Mature Permanent Molars Using Biodentine Versus MTA
Status: UNKNOWN
Conditions: Symptomatic Irreversible Pulpitis
Interventions: PROCEDURE: MTA Pulpotomy.|PROCEDURE: Biodentine Pulpotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Impact of Fish Oil Monoglycerides on the Modulation of Mitochondrial Functions and Lactate Threshold
Status: TERMINATED
Conditions: Healthy Athletes
Interventions: DIETARY_SUPPLEMENT: Eicosapentaenoic acid + Docosahexaenoic acid|DIETARY_SUPPLEMENT: Eicosapentaenoic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: An Exploratory Study to Characterise Changes in Airway Inflammation, Symptoms, Lung Function and Reliever Use in Adult Asthma Patients
Status: COMPLETED
Conditions: Airway Inflammation|Asthma
Interventions: COMBINATION_PRODUCT: SYMBICORT and salbutamol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dovitinib in Combination With Imatinib in Patients With Gastrointestinal Stromal Tumors
Status: WITHDRAWN
Conditions: Gastrointestinal Stromal Tumors
Interventions: DRUG: dovitinib plus imatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Magnetic Resonance Imaging Study and Arthroscopic Biopsy Substudy in Subjects With Active Rheumatoid Arthritis Receiving VX-509, an Oral JAK3 Inhibitor
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: VX-509|DRUG: VX-509 matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Low-dose Interleukin-2 for Treatment of Systemic Lupus Erythematosus
Status: COMPLETED
Conditions: Lupus Erythematosus, Systemic
Interventions: DRUG: Low-dose Aldesleukin (Proleukin®)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Clinical Study of HLX10 Combined With Chemotherapy Versus Placebo Combined With Chemotherapy for Neoadjuvant/Adjuvant Treatment of Gastric Cancer
Status: RECRUITING
Conditions: Gastric Cancer
Interventions: DRUG: HLX10|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Effects of Brensocatib on QT Interval in Healthy Participants
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: Brensocatib|DRUG: Moxifloxacin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Real World Study of Equecabtagene Autoleucel in Subjects With Relapsed and Refractory Multiple Myeloma.
Status: NOT_YET_RECRUITING
Conditions: Relapsed/Refractory Multiple Myeloma
Interventions: DRUG: Equecabtagene Autoleucel
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Research Study to Look Into How Semaglutide, Together With a Lower Dose of Insulin Glargine, Compares to a Higher Dose of Insulin Glargine Alone in People With Type 2 Diabetes (SUSTAIN OPTIMIZE)
Status: ACTIVE_NOT_RECRUITING
Conditions: Diabetes Mellitus, Type 2|Obesity
Interventions: DRUG: Semaglutide|DRUG: Insuline glargine U100 (reduced)|DRUG: Insuline glargine U100 (titrated)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare LY2963016 and US-approved Lantus® After Single Dose Administration to Healthy Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: LY2963016|DRUG: US Approved Lantus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Oral ARV-1801 Given in Combination With Intravenous Ceftazidime or Meropenem for Treatment of Melioidosis in Hospitalized Patients
Status: COMPLETED
Conditions: Melioidosis
Interventions: DRUG: Ceftazidime or meropenem|DRUG: ARV-1801|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dose-Reduced Consolidation Radiation Therapy in Patients With Diffuse Large B-cell Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Diffuse Large B Cell Lymphoma
Interventions: RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dupilumab in Chronic Spontaneous Urticaria
Status: COMPLETED
Conditions: Chronic Spontaneous Urticaria|Recurrent Angioedema
Interventions: DRUG: Dupilumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety & Immunogenicity of 13vPnC in HIV-Infected Subjects Aged 18 or Older Who Were Previously Immunized With 23vPS
Status: COMPLETED
Conditions: HIV Infections|Pneumococcal Infections
Interventions: BIOLOGICAL: 13-valent pneumococcal conjugate vaccine|PROCEDURE: Blood draw
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Prospective Study of the Effect of Treatment of First Time Traumatic Shoulder Anterior Dislocation by Immobilization in External Rotation on the Incidence of Recurrent Dislocation
Status: UNKNOWN
Conditions: Dislocation of the Shoulder
Interventions: DEVICE: Immobilization of the shoulder in external rotation in a soft dressing called universal shoulder immobilizer (USI)|DEVICE: Immobilization of the shoulder in internal rotation in a soft dressing called universal shoulder immobilizer (USI)
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: Assessment of the Safety and Performance of an Elbow Brace in the Prevention of Injuries During Sports Practice
Status: RECRUITING
Conditions: Epicondylitis|Tendonitis Elbow|Elbow Injury
Interventions: DEVICE: Elbow SOFT 300|OTHER: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Adverse Events and Effectiveness of Rapid Acoustic Pulse (RAP) Device in Adult Participants for the Appearance of Cellulite
Status: COMPLETED
Conditions: Cellulite
Interventions: DEVICE: Rapid Acoustic Pulse
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Patient-centered, Optimal Integration of Survivorship and Palliative Care
Status: RECRUITING
Conditions: Stage IV Non-small Cell Lung Cancer|Targeted Therapy|Nonsmall Cell Lung Cancer|Carcinoma, Non-Small-Cell Lung|ALK-positive Non-small Cell Lung Cancer|EGFR Positive Non-small Cell Lung Cancer|Palliative Care|Survivorship
Interventions: BEHAVIORAL: POISE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Multicenter Trial to Evaluate the Insertion Characteristics of the Radiopaque Etonogestrel Implant Using a Next Generation Applicator (34530)(P05702)
Status: COMPLETED
Conditions: Contraception
Interventions: DRUG: Radiopaque Etonogestrel Implant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Determination of Vaginal Colonization and the Effect of an Oral Probiotic (PROSALVAG)
Status: UNKNOWN
Conditions: Microbial Colonization|Dysbiosis|Fertility Issues
Interventions: DIETARY_SUPPLEMENT: FertyBiotic Balance
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Laparoscopic Versus Open Distal Pancreatectomy for Pancreatic Cancer: a Multicenter Randomized Controlled Trial
Status: RECRUITING
Conditions: Pancreas Neoplasm Malignant Resectable
Interventions: PROCEDURE: Laparoscopic distal pancreatectomy|PROCEDURE: open distal pancreatectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimising Ventilatory Strategies by Using Positive Respiratory Integer Measurements
Status: NOT_YET_RECRUITING
Conditions: Hypoxemia|Hypercapnia|Ventilator Associated Pneumonia|Complication of Anesthesia|Postoperative Complications
Interventions: PROCEDURE: Intermittent Positive pressure ventilation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Multiple Dose Study to Evaluate the Safety and Efficacy of MK-2748 in Hepatitis C-Infected Participants (MK-2748-002 AM1)
Status: COMPLETED
Conditions: Hepatitis C
Interventions: DRUG: MK-2748|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Systematic Infants Vaccination Against Rotavirus on Gastroenteritis Hospitalization: a Prospective Study in Brest District, France.
Status: COMPLETED
Conditions: Rotavirus Gastroenteritis
Interventions: BIOLOGICAL: Rotateq vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Recombinant Endostatin Combined With Vinorelbine and Cisplatin in Patients With Advanced Non-small Cell Lung Cancer
Status: COMPLETED
Conditions: Advanced Non-small Cell Lung Cancer
Interventions: DRUG: Placebos|DRUG: Sulijia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Quetiapine on Sleep and Next Day Alertness in People With Obstructive Sleep Apnea
Status: COMPLETED
Conditions: Sleep Apnea, Obstructive
Interventions: DRUG: Quetiapine 50 MG|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Study to Compare the Blood Levels and Safety of Tazemetostat in Participants With Advanced Cancer and Moderate/Severe Liver Impairment to Participants With Advanced Cancer and Normal Liver Function
Status: RECRUITING
Conditions: Hepatic Impairment|Advanced Malignant Solid Tumor
Interventions: DRUG: Tazemetostat
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Visual Quality Change of Eyes Implanted With Diffractive Multifocal Intraocular Lens After Cataract Surgery
Status: UNKNOWN
Conditions: Dry Eye|Vision Disorders|Quality of Life
Interventions: OTHER: Diffractive multifocal IOLs group
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Measurement of Urinary Catabolites of PACs as Biomarkers of Consumption of Cranberry Extracts
Status: COMPLETED
Conditions: Urinary Tract Infections
Interventions: DIETARY_SUPPLEMENT: Cranberry extract
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: First-line Treatment for Femoroacetabular Impingement Syndrome
Status: RECRUITING
Conditions: Femoroacetabular Impingement Syndrome
Interventions: OTHER: Supervised strength exercise intervention|OTHER: Minimal educational intervention (usual care)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Provider Notification for High B-type Natriuretic Peptide Values
Status: COMPLETED
Conditions: Heart Failure
Interventions: OTHER: Clinical Reminder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The CRESCENDO Program (inCRease Physical Exercise and Sport to Combat ENDOmetriosis)
Status: RECRUITING
Conditions: Endometriosis|Quality of Life
Interventions: BEHAVIORAL: Physical activity|BEHAVIORAL: Physical activity and education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Evaluation of Enalapril Versus Placebo in Patients With Diastolic Heart Failure
Status: COMPLETED
Conditions: Heart Failure With Preserved Ejection Fraction|Heart Failure, Congestive
Interventions: DRUG: Enalapril|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Testing a Mindfulness/Acceptance-Based Smartphone App for Nurses Impacted by the COVID-19 Pandemic
Status: UNKNOWN
Conditions: Posttraumatic Stress Disorder
Interventions: BEHAVIORAL: Mindfulness/Acceptance-Based Smartphone App (MABSA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multicenter, Randomized, Double-Blind Parallel-Group, Placebo-Controlled Efficacy Study Comparing 4 Weeks of Treatment With Esomeprazole 20 mg Once Daily to Placebo qd for the Resolution of Upper Abdominal Pain in Patients With Symptomatic Gastroesophageal Reflux Disease (sGERD)
Status: COMPLETED
Conditions: Symptomatic Gastroesophageal Reflux Disease (sGERD)
Interventions: DRUG: Esomeprazole|DRUG: Matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Study of Duodenal Mucosal RF Vapor Ablation in Subjects With Type-2 Diabetes Mellitus
Status: ACTIVE_NOT_RECRUITING
Conditions: Diabetes Mellitus Type 2
Interventions: DEVICE: RF Vapor Ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fluorouracil, Hydroxyurea, Cetuximab and Twice-daily Intensity Radiation Therapy for Advanced Head and Neck Cancer
Status: COMPLETED
Conditions: Head and Neck Cancer|Cancer of the Pharynx|Cancer of the Larynx|Nose Neoplasms|Paranasal Sinus Neoplasms|Cancer of the Oral Cavity
Interventions: DRUG: Cetuximab|DRUG: Hydroxyurea|DRUG: Fluorouracil|PROCEDURE: radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Feasibility for Safety & Device Functionality of SFM Anastomosis Device Used in 3 Procedures (SNAP-S) or (SNAP-PS) or (J-J)
Status: RECRUITING
Conditions: Morbid Obesity
Interventions: DEVICE: Self-Forming Magnetic Anastomosis Device and Delivery System
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: DEcision-making Capacity: Intervention Development & Evaluation in Schizophrenia-spectrum Disorder
Status: UNKNOWN
Conditions: Schizophrenia and Related Disorders|Mental Competency
Interventions: BEHAVIORAL: Self-esteem intervention|BEHAVIORAL: Self-stigma intervention|BEHAVIORAL: Jumping to conclusions intervention|BEHAVIORAL: Control procedure (assessment only)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Single Group Study of the Safety of and Immune Response to a Bird Flu Vaccine (H7N3) in Healthy Adults
Status: COMPLETED
Conditions: Influenza|Virus Diseases
Interventions: BIOLOGICAL: Live Influenza A Vaccine H7N3 (6-2) AA ca Recombinant (A/chicken/British Columbia/CN-6/2004 x A/Ann Arbor/6/60 ca)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Anticoagulation in Patients Suffering From COVID-19 Disease The ANTI-CO Trial
Status: UNKNOWN
Conditions: Anticoagulation in COVID-19 ARDS
Interventions: DRUG: Bivalirudin Injection|DRUG: Standard treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Use of Prophylactic Lubricating Drops After Cataract Surgery
Status: UNKNOWN
Conditions: Dry Eye|Cataract Surgery|Patient Related Outcome Measures|Patient Satisfaction
Interventions: DRUG: AEONTM Repair|OTHER: Routine post-operative eye drops used.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Prognostic Impact of Using High-dose Hydralazine in Severe Systolic Heart Failure With Hemodynamically Significant Mitral Regurgitation
Status: UNKNOWN
Conditions: Systolic Heart Failure Stage D (Disorder)|Mitral Regurgitation
Interventions: DRUG: evidence-based medications vs. high-dose hydralazine + evidence-based medications
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Multiple Chronic Conditions for Older Adults
Status: COMPLETED
Conditions: Chronic Disease
Interventions: OTHER: Treatment as usual (TAU) + Internet|BEHAVIORAL: TAU + ElderTree
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Induction of Mixed Hemopoietic Chimerism in Patients Using Fludarabine, Low Dose TBI, PBSC Infusion and Post Transplant in Immunosuppression w/CSA & Mycophenolate Mofetil
Status: UNKNOWN
Conditions: Post Transplant in Immunosuppression w/CSA & Mycophenolate Mofetil
Interventions: DRUG: Mycophenolate Mofetil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: On Demand Versus Protocol-guided Renal Replacement Therapy for Management of Stage 3 Acute Kidney Injury in Patients With Cirrhosis
Status: UNKNOWN
Conditions: Acute Kidney Injury With Cirrhosis
Interventions: BIOLOGICAL: Protocol Guided Renal Replacement Therapy|BIOLOGICAL: On Demand Renal Replacement Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of a Hydrocolloid Bandage on Pimples
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: Study Cleanser (Neutrogena Ultra Gentle Daily Cleanser with Pro Vitamin B5)|DEVICE: Prototype Ultrathin Hydrocolloid Bandage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Mesh Removal Versus No Mesh Removal for Chronic Groin Pain After Inguinal Hernia Repair
Status: RECRUITING
Conditions: Chronic Groin Pain|Hernia, Inguinal
Interventions: PROCEDURE: Diagnostic laparoscopy and inguinal mesh removal|PROCEDURE: Diagnostic laparoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Umbilical Cord Blood Transplantation in Treating Patients With High-Risk Hematologic Cancer
Status: COMPLETED
Conditions: Graft Versus Host Disease|Leukemia|Lymphoma|Myelodysplastic Syndromes|Myelodysplastic/Myeloproliferative Diseases
Interventions: BIOLOGICAL: anti-thymocyte globulin|DRUG: busulfan|DRUG: cyclosporine|DRUG: melphalan|DRUG: methylprednisolone|PROCEDURE: umbilical cord blood transplantation|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of CAEL-101 in Patients With Mayo Stage IIIa AL Amyloidosis
Status: ACTIVE_NOT_RECRUITING
Conditions: AL Amyloidosis
Interventions: DRUG: CAEL-101|OTHER: Placebo|DRUG: cyclophosphamide, bortezomib, and dexamethasone (CyBorD) regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Filgotinib in Long-Term Extension Study of Adults With Ulcerative Colitis
Status: ACTIVE_NOT_RECRUITING
Conditions: Ulcerative Colitis
Interventions: DRUG: Filgotinib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Luteal Phase Support With Progesterone Versus Estrogen and Progesterone on Pregnancy Rates
Status: UNKNOWN
Conditions: Unexplained Infertility|Mild Male Factor
Interventions: DRUG: Luteal support with progesterone only|DRUG: Luteal support with estrogen + progesterone|PROCEDURE: Insemination without luteal support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Term Delivery Versus Expectant Management of the Large for Gestational Age Fetus
Status: WITHDRAWN
Conditions: Macrosomia, Fetal|Labor Induction
Interventions: PROCEDURE: Labor induction at 37.0 weeks to 37.6 weeks of gestation|PROCEDURE: Expectant monitoring and delivery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Albright Hereditary Osteodystrophy: Natural History, Growth, and Cognitive/Behavioral Assessments
Status: RECRUITING
Conditions: Pseudohypoparathyroidism Type 1A|Albright Hereditary Osteodystrophy|Pseudopseudohypoparathyroidism
Interventions: BEHAVIORAL: Neurocognitive and psychosocial testing
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Postoperative Analgesic Effect of Esketamine
Status: COMPLETED
Conditions: Gynecological; Surgery (Previous), Affecting Fetus or Newborn, Due to Obstructed Labor|Analgesia
Interventions: DRUG: 2 mg morphine sulfate|DRUG: 0.25mg/kg esketamine|DRUG: 0.25mg/kg of esketamine in combination with 2 mg morphine sulfate|DRUG: 0.25mg/kg of esketamine in combination with 1 mg morphine sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Population and Sex-specific Troponin Cutoffs for Ruling Out Acute Myocardial Infarction
Status: RECRUITING
Conditions: Coronary Syndrome, Acute|Coronary Artery Disease|Myocardial Infarction
Interventions: DIAGNOSTIC_TEST: Implementation of the new population and sex-specific 99th percentile URL for cardiac troponin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effect of Supplementation of Flaxseed, Hesperidin, Flaxseed and Hesperidin Together in Metabolic Syndrome
Status: UNKNOWN
Conditions: Metabolic Syndrome
Interventions: DIETARY_SUPPLEMENT: hesperidin|DIETARY_SUPPLEMENT: hesperidin and flaxseed|DIETARY_SUPPLEMENT: flaxseed|OTHER: control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ibudilast for the Treatment of Alcohol Use Disorder
Status: COMPLETED
Conditions: Alcohol Use Disorder
Interventions: DRUG: Ibudilast|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Trial Comparing Ferric(III)Carboxymaltose Infusion With Oral Iron Suppletion as Treatment of Anaemia
Status: UNKNOWN
Conditions: Anemia|Colorectal Carcinoma|Surgery
Interventions: DRUG: Ferrous fumarate|DRUG: ferric(III)carboxymaltose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mifepristone Effects on Glucose Intolerance in Obese/Overweight Adults
Status: COMPLETED
Conditions: Endocrine Disease|Diabetes
Interventions: DRUG: Mifepristone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Minimally Invasive Surgery After Neoadjuvant Chemotherapy for the Treatment of Stage IIIC-IV Ovarian, Primary Peritoneal, or Fallopian Tube Cancer, LANCE Trial
Status: RECRUITING
Conditions: Advanced Ovarian Carcinoma|Fallopian Tube Clear Cell Adenocarcinoma|Fallopian Tube Endometrioid Tumor|Fallopian Tube Serous Neoplasm|Fallopian Tube Transitional Cell Carcinoma|Ovarian Clear Cell Adenocarcinoma|Ovarian Endometrioid Adenocarcinoma|Ovarian Serous Adenocarcinoma|Ovarian Transitional Cell Carcinoma|Primary Peritoneal Clear Cell Adenocarcinoma|Primary Peritoneal Endometrioid Adenocarcinoma|Primary Peritoneal Serous Adenocarcinoma|Primary Peritoneal Transitional Cell Carcinoma|Stage IIIC Fallopian Tube Cancer AJCC v8|Stage IIIC Ovarian Cancer AJCC v8|Stage IIIC Primary Peritoneal Cancer AJCC v8|Stage IV Fallopian Tube Cancer AJCC v8|Stage IV Ovarian Cancer AJCC v8|Stage IV Primary Peritoneal Cancer AJCC v8|Stage IVA Fallopian Tube Cancer AJCC v8|Stage IVA Ovarian Cancer AJCC v8|Stage IVA Primary Peritoneal Cancer AJCC v8|Stage IVB Fallopian Tube Cancer AJCC v8|Stage IVB Ovarian Cancer AJCC v8|Stage IVB Primary Peritoneal Cancer AJCC v8
Interventions: DRUG: Chemotherapy|PROCEDURE: Laparotomy|PROCEDURE: Minimally Invasive Surgery|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy With or Without Bevacizumab in Treating Patients With Nonmetastatic Breast Cancer
Status: UNKNOWN
Conditions: Breast Cancer|Cardiac Toxicity|Perioperative/Postoperative Complications
Interventions: BIOLOGICAL: bevacizumab|DRUG: cyclophosphamide|DRUG: docetaxel|DRUG: epirubicin hydrochloride|DRUG: fluorouracil|PROCEDURE: assessment of therapy complications|PROCEDURE: neoadjuvant therapy|PROCEDURE: quality-of-life assessment|PROCEDURE: therapeutic conventional surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Function-metabolism Coupling in Decision-making Confidence Neural Network of Obsessive-compulsive Disorder
Status: NOT_YET_RECRUITING
Conditions: Obsessive-Compulsive Disorder
Interventions: DEVICE: Repetitive transcranial magnetic stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Cardiovascular Structure and Function in the Mucopolysaccharidoses
Status: RECRUITING
Conditions: Mucopolysaccharidoses|Carotid Disease|Cardiac Disease|Inflammation
Interventions: DIAGNOSTIC_TEST: Carotid ultrasonography|DIAGNOSTIC_TEST: Echocardiography, transthoracic|PROCEDURE: Venipuncture
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Longitudinal Endotyping Of Atopic Dermatitis Through Transcriptomic Skin Analysis
Status: RECRUITING
Conditions: Atopic Dermatitis
Interventions: BIOLOGICAL: Dupilumab|DRUG: Vanicream- Dupilumab-naïve|DRUG: Triamcinolone Acetonide|DRUG: Hydrocortisone|DRUG: Vanicream- Active|DRUG: Vanicream- Experienced Dupilumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Local Anaesthetic Dilution on the Characteristics of Ultrasound Guided Axillary Brachial Plexus Block
Status: COMPLETED
Conditions: Brachial Plexus Blockade
Interventions: PROCEDURE: Axillary brachial plexus block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Study of Diclofenac Capsules to Treat Pain Following Bunionectomy
Status: COMPLETED
Conditions: Other Acute Postoperative Pain
Interventions: DRUG: Diclofenac Test (lower dose)|DRUG: Diclofenac Test (upper dose)|DRUG: Celecoxib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study for Ginkgolides Meglumine Injection Skin Testing.
Status: COMPLETED
Conditions: Allergy
Interventions: DRUG: 0.1mg/ml Ginkgolides Meglumine Injection|DRUG: 1mg/ml Ginkgolides Meglumine Injection|DRUG: 5mg/ml Ginkgolides Meglumine Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Moisturising Creams on Skin Moisture in Atopic Dermatitis
Status: COMPLETED
Conditions: Dermatitis, Atopic
Interventions: OTHER: Aqualan L, Aqualan Plus, Aqualan L + glycerol ad 20%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Open Label Study of IV Brincidofovir in Adult Transplant Recipients With Adenovirus Viremia
Status: WITHDRAWN
Conditions: Adenovirus
Interventions: DRUG: Brincidofovir|DRUG: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CLIC-2201 for the Treatment of Relapsed/Refractory B Cell Malignancies
Status: NOT_YET_RECRUITING
Conditions: B-Cell Leukemia|Non-Hodgkin's Lymphoma|B-cell Acute Lymphoblastic Leukemia|Diffuse Large B Cell Lymphoma|High-grade B-cell Lymphoma|Primary Mediastinal Large B-cell Lymphoma (PMBCL)|Mantle Cell Lymphoma|B-cell Lymphoma
Interventions: BIOLOGICAL: CLIC-2201
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long-term Efficacy of Metacognitive Training for Depression (D-MCT)
Status: COMPLETED
Conditions: Unipolar Depression
Interventions: BEHAVIORAL: D-MCT|BEHAVIORAL: Health Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Safety/Tolerability and PK Study With Azstarys® in Children With ADHD
Status: ACTIVE_NOT_RECRUITING
Conditions: Attention Deficit/Hyperactivity Disorder
Interventions: DRUG: Serdexmethylphenidate (SDX) and dexmethylphenidate (d-MPH)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Navtemadlin add-on to Ruxolitinib in JAK Inhibitor-Naïve Patients With Myelofibrosis Who Have a Suboptimal Response to Ruxolitinib
Status: RECRUITING
Conditions: Myelofibrosis|Post-PV MF|Post-ET Myelofibrosis|Primary Myelofibrosis|MF
Interventions: DRUG: Navtemadlin|DRUG: Navtemadlin placebo|DRUG: Ruxolitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Polyp Detection With The Peerscope System™
Status: COMPLETED
Conditions: Colon Polyps and Adenomas|Colon Cancer
Interventions: DEVICE: Colonoscopy done with:PeerMedical System and Olympus/Pentax/Fuji colonoscopy system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SCREENING
Clinical trial: Individual Approach for Bowel Preparation Before Colonoscopy
Status: COMPLETED
Conditions: Split-dose Bowel Preparation|Polyethylene Glycol Solution|Risk Factors Inadequate Preparation
Interventions: OTHER: individual preparation for colonoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Gentamicin Therapy for Recessive Dystrophic Epidermolysis Bullosa (RDEB) Nonsense Mutation Patients
Status: COMPLETED
Conditions: Recessive Dystrophic Epidermolysis Bullosa
Interventions: DRUG: Gentamicin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SCI-Lynx: A Mobile Platform for Physical Activity Social Support for People With SCI Pilot Study
Status: RECRUITING
Conditions: Spinal Cord Injuries
Interventions: BEHAVIORAL: SCI-Lynx Mobile Application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: PREVAIL-TA: Placement of Aortic Balloon Expandable Transcatheter Valves Trial (Europe)
Status: COMPLETED
Conditions: Aortic Valve Stenosis
Interventions: DEVICE: SAPIEN XT™ Transapical aortic valve replacement
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RESET-BRAIN: REhabilitation of SleEp and cogniTive Impairment in BReast Cancer Survivors Using an App-based Intervention
Status: NOT_YET_RECRUITING
Conditions: Insomnia|Cognitive Impairment|Breast Cancer
Interventions: BEHAVIORAL: Cognitive Behavioral Therapy for Insomnia (CBT-I)|BEHAVIORAL: Sleep hygiene education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Simulating Laparoscopy With an Eye Patch
Status: COMPLETED
Conditions: Laparoscopic Training
Interventions: DEVICE: Computerized Laparoscopic Trainer|DEVICE: Box trainer with eye patch
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Preventing Cholestasis Using SMOFLipid®
Status: COMPLETED
Conditions: Cholestasis|Psychomotor Disorders, Developmental
Interventions: DRUG: SMOFLIPID|DRUG: INTRALIPID
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Crossover Study to Determine the 24 Hour Lung Function Profile of Indacaterol in Patients With Moderate-to-severe Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Indacaterol 300 μg|DRUG: Placebo to indacaterol|DRUG: Salmeterol 50 μg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Surgical Pain After Inguinal Hernia Repair (SPAIHR)
Status: COMPLETED
Conditions: Pain, Postoperative|Hernia, Inguinal
Interventions: DRUG: Pregabalin|DRUG: placebo|DRUG: Pregabalin|DRUG: Pregabalin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Aspirin Resistance in Coronary Artery Disease
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DRUG: enteric-coated aspirin|DRUG: Chewable aspirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Botox Injection for Lower Extremity Lengthening and Deformity Correction Surgery
Status: COMPLETED
Conditions: Unequal Length of Limbs; Congenital|Lower Extremity Deformities, Congenital
Interventions: DRUG: Botulinum toxin A injection|DRUG: saline injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multitarget Stool FIT-DNA Study for Colorectal Cancer Early Screening in China
Status: COMPLETED
Conditions: Colorectal Cancer|Adenomatous Polyps|Adenoma|Advanced Adenoma
Interventions: DIAGNOSTIC_TEST: Multitarget stool FIT-DNA test - ColoClear|DIAGNOSTIC_TEST: FIT|PROCEDURE: Colonoscopy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Prospective Aneurysm Trial: High Angle Aorfix™ Bifurcated Stent Graft
Status: COMPLETED
Conditions: Abdominal Aortic Aneurysms
Interventions: PROCEDURE: Open surgical repair|DEVICE: Stent Graft
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ischemic Heart Disease in Male With Prostate Adenocarcinoma
Status: UNKNOWN
Conditions: Ischemic Heart Disease|Prostate Adenocarcinoma
Interventions: DIAGNOSTIC_TEST: ISCHEMIC HEART DISEASE diagnostic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Decision Making About Participating in Pharmacokinetic Studies in Patients Enrolled in a Phase I Treatment Clinical Trial
Status: COMPLETED
Conditions: Brain and Central Nervous System Tumors|Leukemia|Unspecified Adult Solid Tumor, Protocol Specific|Unspecified Childhood Solid Tumor, Protocol Specific
Interventions: OTHER: questionnaire administration|PROCEDURE: psychosocial assessment and care
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Temsirolimus Adventitial Delivery to Improve Angiographic Outcomes Below the Knee (TANGO)
Status: UNKNOWN
Conditions: Chronic Limb Ischemia
Interventions: DRUG: Temsirolimus|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Vaccine Therapy of Prostate Cancer Patients With Recombinant Soluble Prostate-Specific Membrane Antigen (Rs-PSMA) Plus the Immunological Adjuvant Alhydrogel
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: BIOLOGICAL: rsPSMA protein plus Alhydrogel® vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Effectiveness of Cognitive Adaptation Training in Early Intervention for Psychosis
Status: COMPLETED
Conditions: Psychosis
Interventions: BEHAVIORAL: Cognitive Adaptation Training|BEHAVIORAL: Action Based Cognitive Remediation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cervical Spine; Movement Before and After Anterior Cervical Discectomy, With or Without a Cervical Disc Prosthesis
Status: COMPLETED
Conditions: Diskectomy|Intervertebral Disk Displacement
Interventions: DEVICE: Activ C disc prosthesis|PROCEDURE: Anterior cervical discectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GLOBAL LEADERS: A Clinical Study Comparing Two Forms of Anti-platelet Therapy After Stent Implantation
Status: COMPLETED
Conditions: Coronary Artery Disease (CAD)
Interventions: DRUG: Ticagrelor|DRUG: Acetylsalicylic Acid|DRUG: Clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adjunctive Treatment for Decreasing Symptoms of Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder
Interventions: DRUG: d-cycloserine|DRUG: glycine|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Phase III Trial of Gemcitabine, Curcumin and Celebrex in Patients With Metastatic Colon Cancer
Status: UNKNOWN
Conditions: Colon Neoplasm
Interventions: DRUG: CELECOXIB|DRUG: CURCUMIN
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Study to Test Different Doses of BI 1569912 in People With Depression Who Take Anti-depressive Medicine
Status: RECRUITING
Conditions: Depressive Disorder, Major
Interventions: DRUG: BI 1569912|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: r-hGH Liquid Multidose Versus Freeze-dried Multidose Bioequivalence Trial
Status: COMPLETED
Conditions: Growth Failure|Growth Hormone Deficiency
Interventions: BIOLOGICAL: r-hGH liquid (Saizen)|BIOLOGICAL: r-hGH liquid (Saizen)|BIOLOGICAL: r-hGH freeze-dried
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Phase 1/2 Study of E6005 in Pediatric Subjects With Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: E6005 0.05%|DRUG: Placebo|DRUG: E6005 0.2%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Dexmedetomidine During Opioid Free Anesthesia on Postoperative Recovery After Gastrectomy
Status: COMPLETED
Conditions: Gastric Cancer
Interventions: DRUG: Dexmedetomidine|DRUG: Remifentanil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: This Trial Evaluates Safety, Pharmacokinetic Profile and Anti-viral Response of BI 207127 and BI 201335 for Patients With Chronic Hepatitis C
Status: COMPLETED
Conditions: Hepatitis C, Chronic
Interventions: DRUG: BI 207127 NA|DRUG: peginterferon|DRUG: Ribavirin|DRUG: Ribavirin|DRUG: BI 207127 NA|DRUG: BI 201335 NA|DRUG: BI 201335 NA|DRUG: peginterferon
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT