pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Effect of Soy Intake on Cardiovascular Disease Biomarkers in Subclinical Hypothyroid Participants
Status: WITHDRAWN
Conditions: Cardiovascular Disease|Subclinical Hypothyroid
Interventions: DIETARY_SUPPLEMENT: soy protein isolate (SPI)|DIETARY_SUPPLEMENT: milk protein isolate (MPI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Consensus-based Algorithms to Address Opioid Misuse Behaviors Among Individuals Prescribed LTOT
Status: ACTIVE_NOT_RECRUITING
Conditions: Opioid Misuse|Chronic Pain
Interventions: BEHAVIORAL: Pilot study of algorithms implementation package
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Post Operative Pain and Level of Endotoxins With Calcium Hydroxide and Calcium Hydroxide Mixed With Chlorhexidine in Treating Necrotic Teeth
Status: UNKNOWN
Conditions: Necrotic Pulp
Interventions: DRUG: Chlorhexidine 2% gel - Calcium Hydroxide Paste - Non-Setting|DRUG: Calcium Hydroxide Paste - Non-Setting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Convalescent Plasma in ICU Patients With COVID-19-induced Respiratory Failure
Status: TERMINATED
Conditions: Covid-19|Sars-CoV2
Interventions: BIOLOGICAL: Multiple Doses of Anti-SARS-CoV-2 convalescent plasma
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Does 3D Laparoscopy Improve Vaginal Cuff Suture Time?
Status: COMPLETED
Conditions: Uterine Fibroids|Abnormal Uterine Bleeding|Pelvic Pain|Adenomyosis
Interventions: DEVICE: Storz 3D Laparoscopy System|DEVICE: 2D Laparoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Carboplatin/Nab-Paclitaxel and Pembrolizumab in NSCLC
Status: TERMINATED
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: Carboplatin|DRUG: Nab-paclitaxel|DRUG: MK-3475 (Phase I)|DRUG: MK-3475 (Phase II)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: QSPainRelief-STRAT
Status: NOT_YET_RECRUITING
Conditions: Chronic Pain|Analgesia|Adverse Drug Event|Drug Interaction
Interventions: COMBINATION_PRODUCT: Opioid drug + CNS-acting add-on drug
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Iodine-131 Anti-B1 Antibody for NHL Patients With Greater Than 25% Bone Marrow Involvement
Status: UNKNOWN
Conditions: Non-Hodgkin's Lymphoma
Interventions: DRUG: Iodine-131 Anti-B1 Antibody
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Does a Single Steroid Injection Reduce the Formation of Postmastectomy Seroma
Status: UNKNOWN
Conditions: Breast Neoplasms|Mastectomy
Interventions: DRUG: Solu-medrol 125 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Study of ASP1948, Targeting an Immune Modulatory Receptor, in Japanese Patients With Advanced Solid Tumors
Status: COMPLETED
Conditions: Locally Advanced (Unresectable) or Metastatic Solid Tumor Malignancies
Interventions: DRUG: ASP1948
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nitric Oxide Donor Isosorbide Mono Nitrate for Cervical Ripening in Induction of Labor
Status: COMPLETED
Conditions: Induction of Labor Affected Fetus / Newborn
Interventions: DRUG: isosorbide mononitrate|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Daily Co-trimoxazole Prophylaxis to Prevent Malaria in Pregnancy
Status: TERMINATED
Conditions: Malaria in Pregnancy
Interventions: DRUG: Cotrimoxazole|DRUG: Sulfadoxine-pyrimethamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Trial of Ultrahypofractionated Focal Salvage Radiotherapy for Isolated Prostate Bed Recurrence After Radical Prostatectomy
Status: RECRUITING
Conditions: Recurrent Prostate Cancer
Interventions: RADIATION: Ultrahypofractionated salvage radiotherapy to a local recurrence after radical prostatectomy|DRUG: Androgen deprivation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SUV PDL1/PD1 in Sun Damaged & Sun Protected Human Skin of Participants
Status: RECRUITING
Conditions: Other Skin Changes Due to Chronic Exposure to Nonionizing Radiation
Interventions: OTHER: Solar Simulated Light
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effects of a Prostaglandin Inhibitor on Ovulation and the Menstrual Cycle
Status: COMPLETED
Conditions: Ovulation (Follicular Rupture Yes/no)|Menstrual Cycles (Total Length, Bleeding Days)|Gonadotropin and Ovarian Hormone Levels (FSH, LH, E2, P)
Interventions: DRUG: Celebrex|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Postprandial Effects of High-fat Meals With Different Dairy Products on Lipid Metabolism and Inflammation
Status: COMPLETED
Conditions: Healthy|Overweight|Obesity
Interventions: OTHER: Butter|OTHER: Cheese|OTHER: Whipped cream|OTHER: Sour cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Ultrasound Guided Catheter Length Survivability
Status: COMPLETED
Conditions: Catheter Complications
Interventions: DEVICE: Standard Long IV 4.78 cm 20 g catheter|DEVICE: Ultra-Long IV 6.35 cm 20 g catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Pitavastatin on Insulin Sensitivity and Liver Fat
Status: COMPLETED
Conditions: Obesity|Fatty Liver, Nonalcoholic
Interventions: DRUG: pitavastatin|OTHER: PLACEBO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Sulawesi Propolis Extract on Lesion Growth, Apoptotic and Inflammatory Activity of the Rat Endometriosis Tissue
Status: COMPLETED
Conditions: Endometriosis; Peritoneum|Endometriosis
Interventions: DRUG: Dienogest|DRUG: Propolis|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phenobarbital Versus Valproate for Generalized Convulsive Status Epilepticus
Status: UNKNOWN
Conditions: Generalized Convulsive Status Epilepticus
Interventions: DRUG: Phenobarbital|DRUG: Valproate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Comparison of AVF Versus AVG in Elderly Patients Starting Dialysis
Status: COMPLETED
Conditions: Chronic Kidney Disease|Endstage Renal Disease
Interventions: PROCEDURE: Arteriovenous Fistula (AVF)|PROCEDURE: Arteriovenous Graft (AVG)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment for Stress and Mixed Urinary Incontinence and Vaginal Vault Prolapse
Status: COMPLETED
Conditions: Urinary Incontinence, Stress|Mixed Incontinence|Vaginal Vault Prolapse
Interventions: DEVICE: Vaginal Sling
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Triple Atria Extrastimuli vs Pulmonary Vein Isolation Alone in Persistent Atrial Fibrillation
Status: ACTIVE_NOT_RECRUITING
Conditions: Atrial Fibrillation, Persistent
Interventions: PROCEDURE: pulmonary vein isolation and targeted radiofrequency ablation|PROCEDURE: pulmonary vein isolation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Norepinephrine Bolus Doses for Management of Post-spinal Hypotension During Cesarean Delivery
Status: COMPLETED
Conditions: Cesarean Section Complications|Spinal Anesthetic Toxicity
Interventions: DRUG: Norepinephrine 6 mcg|DRUG: Norepinephrine 10 mcg|DRUG: Norepinephrine infusion|DRUG: Bupivacaine hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Bioavailability and Skin Absorption of CBD and THC From GT4 Technology in Healthy Adults
Status: COMPLETED
Conditions: Biological Availability|Skin Absorption|CBD|THC
Interventions: COMBINATION_PRODUCT: CBD and THC with GT4 technology
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: RCT to Evaluate the Efficacy and Safety of Ivy Leaves Cough Liquid vs. Placebo in the Treatment of Acute Cough
Status: COMPLETED
Conditions: Acute Cough
Interventions: DRUG: Ivy Leaves Cough Liquid|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Brain Research and Integrative Neuroscience Network for COVID-19
Status: RECRUITING
Conditions: Cognitive Training|Transcranial Direct Current Stimulation
Interventions: COMBINATION_PRODUCT: Combination of tDCS (device) with cognitive training (behavioral)|BEHAVIORAL: Categorization Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Phase Ia Safety and Tolerability Study of BL-001
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: BL-001|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Ultravision Visual Clearing System in Laparoscopic Hysterectomy and Myomectomy
Status: COMPLETED
Conditions: Pain|Hysterectomy|Myomectomy
Interventions: DEVICE: Ultravision System|PROCEDURE: Laparoscopic Hysterectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparison of Endothelial Dysfunction (BMS vs SES) in the Same Patient With Multiple Coronary Artery Lesions
Status: COMPLETED
Conditions: Endothelial Dysfunction
Interventions: DRUG: intracoronary infusion of acetylcholine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasonographic Assessment of Neck Vessels as Predictors of Spinal Anesthesia Induced Hypotension in Elderly
Status: COMPLETED
Conditions: Post-spinal Hypotension
Interventions: DEVICE: IJV Ultrasonography|DEVICE: Carotid Intima Media Thickness|PROCEDURE: Spinal anesthesia
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Albumin 4 gr/L vs 8 gr/L in the Prevention of Post-Paracentesis Circulatory Dysfunction
Status: UNKNOWN
Conditions: Tense Ascites in Cirrhosis
Interventions: DRUG: albumin 4 gr/L ascites removed|DRUG: albumin 8 gr/L ascites removed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Performance of Two Sclera Fixated Intraocular Lens Concepts
Status: COMPLETED
Conditions: Cataract Complicated|Cataract Complications Operations
Interventions: DEVICE: IOL Master 700|DEVICE: Casia-2|DEVICE: MS-39|DEVICE: OSIRIS|DEVICE: Autorefractor|DIAGNOSTIC_TEST: Subjective Refraction
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Vitamin A Bioavailability in Lactating Women With Marginal Vitamin A Status
Status: COMPLETED
Conditions: Vitamin A Deficiency
Interventions: OTHER: 0 mg retinol activity equivalents|OTHER: 12 mg of BC|OTHER: 6 mg of CX|OTHER: 1.0 mg RAE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Xenon in Off-pump Coronary Artery Bypass Graft Surgery
Status: COMPLETED
Conditions: Coronary Artery Disease|Anesthesia
Interventions: DRUG: Xenon|DRUG: sevoflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Acupuncture to Endothelial Dysfunction Induced by Ischemia-reperfusion Injury
Status: UNKNOWN
Conditions: Healthy
Interventions: DEVICE: Active acupuncture|DEVICE: Sham acupuncture|DRUG: Euglucon 5mg|DRUG: Celebrex 200mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Validation of a Physiological Based Pharmacokinetic Model by the Study of Paracetamol Distribution in the Brain Compartments in Brain Injured Patients
Status: COMPLETED
Conditions: Brain Injured Patients
Interventions: DRUG: Paracetamol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preventing Postpartum Depression in Prenatal Care
Status: WITHDRAWN
Conditions: Post-partum Depression
Interventions: BEHAVIORAL: Bellevue ROSE Intervention|BEHAVIORAL: Psycho-education session and usual, Standard of care Control|BEHAVIORAL: One Psycho-education session and usual, standard of care Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effectiveness of Pelvic Floor Exercise to Prevent LARS (Low Anterior Resection Syndrome)
Status: RECRUITING
Conditions: Prevention|LARS - Low Anterior Resection Syndrome|Pelvic Floor Disorders|Rectal Cancer|Low Anterior Resection
Interventions: PROCEDURE: Pelvic floor exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: CO2 Removal in Severe Acute exacerbatIons of Chronic Obstructive Lung Diseases
Status: ACTIVE_NOT_RECRUITING
Conditions: COPD Acute Exacerbation
Interventions: DEVICE: ECCO2R
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Gentamicin Versus Clindamycin Versus Normal Saline Lavage in Axilla
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Irrigation with gentamicin solution|DRUG: Irrigation with Clindamycin solution|DRUG: Irrigation with Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Comparison of Functional Recovery After Distal Intra-articular Radius Fracture With a Dorsal Tilt Treated With an Anterior Plate Versus a Posterior Plate
Status: TERMINATED
Conditions: Distal Intra-articular Radius Fracture With a Dorsal Tilt
Interventions: OTHER: DASH score|PROCEDURE: X-ray|PROCEDURE: posterior osteosynthesis|PROCEDURE: Anterior osteosynthesis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hand Rehabilitation Study for Stroke Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Upper Extremity Paresis|Disability Physical|Chronic Stroke|Motor Disorders
Interventions: DEVICE: Somatosensory Electrical Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Empagliflozin Versus Sitagliptin in Patients With Type 2 Diabetes
Status: WITHDRAWN
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Empagliflozin|DRUG: Placebo|DRUG: Sitagliptin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of CD22 CAR-T Cells for Relapsed or Refractory Acute Lymphoblastic Leukemia
Status: UNKNOWN
Conditions: B-ALL
Interventions: BIOLOGICAL: CD22 CAR-T
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Diagnostic Sensitivity and Specificity of iStatis Syphilis Ab Test at the Point- Of-Care Sites
Status: COMPLETED
Conditions: Syphilis Infection|Syphilis
Interventions: DEVICE: iStatis Syphilis Ab Test
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SCREENING
Clinical trial: Reading; Through the Eyes of a University Student
Status: ENROLLING_BY_INVITATION
Conditions: Visual Stress|Meares-Irlen Syndrome|Reading Difficulties
Interventions: DEVICE: Precision tinted spectacle lenses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Tamoxifen and Raloxifene (STAR) for the Prevention of Breast Cancer in Postmenopausal Women
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Raloxifene|DRUG: Tamoxifen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Communication Bridge: A Person-centered Internet-based Intervention for Individuals With Primary Progressive Aphasia
Status: COMPLETED
Conditions: Primary Progressive Aphasia
Interventions: BEHAVIORAL: Communication Bridge™|BEHAVIORAL: Evidence-Based Impairment Focused
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Implementation of the ProACTIVE Toolkit in the Hospital and Community Setting
Status: ACTIVE_NOT_RECRUITING
Conditions: Spinal Cord Injuries
Interventions: OTHER: SCI ProACTIVE Coaching (objective 1)|BEHAVIORAL: Implementation Intervention (objective 2)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Skew Flap vs Long Posterior Flap for Below Knee Amputation Early and Short- Term Outcomes
Status: NOT_YET_RECRUITING
Conditions: Diabetic Foot|Ischemic Leg
Interventions: PROCEDURE: Below knee amputation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Art Therapy on Self-Reported Pain and Anxiety Scores of Patients Waiting to Be Seen in the Emergency Department
Status: RECRUITING
Conditions: Anxiety|Pain
Interventions: BEHAVIORAL: Nature Coloring Packet|BEHAVIORAL: Geometric Shape Coloring Packet|BEHAVIORAL: Activity Book|BEHAVIORAL: Blank Paper and Pencil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study for Effectiveness Evaluation of Panax Ginseng, Vitamins and Minerals (Natugerin®) in Improvement of Stress and Fatigue
Status: UNKNOWN
Conditions: Stress|Fatigue
Interventions: DIETARY_SUPPLEMENT: NatusGerin|OTHER: Placebo capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Optimization Trial of Decision Partnering Intervention for Advanced Cancer Family Caregivers
Status: COMPLETED
Conditions: Family Caregivers|Cancer
Interventions: BEHAVIORAL: CASCADE (CAre Supporters Coached to be Adept DEcision partners)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Inulin for Infections in the Intensive Care Unit
Status: ACTIVE_NOT_RECRUITING
Conditions: Antibiotic Resistant Infection|Nosocomial Infection|Pathogen Transmission|Nutrition Disorders|Critical Illness|Sepsis
Interventions: DRUG: Inulin Oral Suspension|DRUG: Placebo Oral Suspension|DRUG: Broad-spectrum antibiotics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study to Evaluate Two Lenalidomide Dose Regimens With Low Dose Dexamethasone for the Treatment Relapsed Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Lenalidomide 15mg|DRUG: Lenalidomide 25mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose Escalation & Expansion Study of Oral VRx-3996 & Valganciclovir in Subjects With EBV-Associated Lymphoid Malignancies
Status: COMPLETED
Conditions: Epstein-Barr Virus Associated Lymphoma|Lymphoproliferative Disorders
Interventions: DRUG: VRx-3996|DRUG: Valganciclovir
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Transcutaneous Vs End-tidal CO2 Pressure Measurements in Hyperventilation Syndrome Diagnosis
Status: COMPLETED
Conditions: Hyperventilation Syndrome|Hypocapnia|Alkalosis, Respiratory|Hyperventilation
Interventions: DIAGNOSTIC_TEST: Simultaneous Transcutaneous and End-tidal CO2 measurements
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety Study of a Helper Peptide Vaccine Plus Adjuvant Combinations for the Treatment of Melanoma
Status: TERMINATED
Conditions: Melanoma
Interventions: BIOLOGICAL: 6MHP|DRUG: Montanide ISA-51|DRUG: polyICLC|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Safety of Desloratadine With Levocetirizine in Treatment of Chronic Idiopathic Urticaria
Status: UNKNOWN
Conditions: Chronic Idiopathic Urticaria|Urticaria
Interventions: DRUG: Denosin® and Xyzal®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Axillary Plexus Block in a High Resolution MRI
Status: COMPLETED
Conditions: Nerve Block|Magnetic Resonance Imaging
Interventions: PROCEDURE: Active Comparator: Arm 1: catheter injection|PROCEDURE: Active Comparator: Arm 2: transarterial injection|PROCEDURE: Active Comparator: Arm 3: catheter and transarterial injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: How Does Altering the Timing of Pre-exercise Low-dose Caffeine Ingestion Affect Endurance Exercise Performance
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: Caffeine powder -60|OTHER: Caffeine powder -30|OTHER: Caffeine powder 0|OTHER: Placebo powder -60|OTHER: Placebo powder -30|OTHER: Placebo powder 0
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Mechanical Vibration on Children With Cerebral Palsy
Status: COMPLETED
Conditions: Cerebral Palsy|Spastic Hemiplegic Cerebral Palsy
Interventions: DEVICE: Vibration Group|OTHER: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Does Dehydro Epiandrosterone (DHEA) Improve Pregnancy Rate in Women Undergoing IVF/ICSI With Expected Poor Ovarian Response?
Status: COMPLETED
Conditions: Subfertility
Interventions: DRUG: DHEA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study on The Value of Endobronchial Ultrasound Elastography in The Diagnosis of Thoracic Lesions
Status: UNKNOWN
Conditions: Thoracic Lesions
Interventions: DEVICE: endobronchial ultrasound elastography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Healing Effect of Ziziphus Honey on Extracted Tooth Socket in Humans by Evaluating the Levels of BMP-2 and OPN
Status: COMPLETED
Conditions: Healing Wound
Interventions: DRUG: ziziphus honey
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phase I Study LJM716 Combined With Trastuzumab in Patients With HER2 Overexpressing Metastatic Breast or Gastric Cancer
Status: COMPLETED
Conditions: Advanced HER2-positive Breast Cancer or Gastric Cancer
Interventions: DRUG: LJM716|DRUG: Trastuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment Evaluation of Neuromodulation for Tinnitus - Stage A2
Status: COMPLETED
Conditions: Tinnitus
Interventions: DEVICE: PS1-PS4|DEVICE: PS6-PS10|DEVICE: PS7-PS4|DEVICE: PS9-PS6
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Safety and Tolerability Study of Neural Stem Cells (NR1) in Subjects With Chronic Ischemic Subcortical Stroke (ISS)
Status: ACTIVE_NOT_RECRUITING
Conditions: Ischemic Stroke
Interventions: BIOLOGICAL: Neural Stem Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Goals of Care Discussion for Patients With Advanced Lung and Gastrointestinal Cancer in the Emergency Department of a Comprehensive Cancer Center
Status: RECRUITING
Conditions: Lung Cancer|Gastrointestinal Cancer
Interventions: OTHER: Standard of Care (Acute Cancer Care Center)|OTHER: Standard of Care (Goals of Care)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Erythrocyte-bound Apolipoprotein B After Withdrawal of Statin Therapy
Status: COMPLETED
Conditions: Hyperlipidemia|Atherosclerosis
Interventions: DRUG: Temporary discontinuation of statin therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Electroacupuncture in Symptom Management After Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy
Status: NOT_YET_RECRUITING
Conditions: Cancer
Interventions: OTHER: Electroacupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Phase 1 Study of PLN-101095 in Adults With Advanced or Metastatic Solid Tumors
Status: RECRUITING
Conditions: Metastatic Solid Tumor
Interventions: DRUG: PLN-101095|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: [11C]MK-6884 Positron Emission Tomography (PET) Tracer Validation Trial (MK-6884-001)
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: [11C]MK-6884
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Usefulness of Non-invasive Pulse Co-oximetry Haemaglobin Measurements in Critically Ill Black Patients
Status: COMPLETED
Conditions: Critically Ill Black Patients
Interventions: OTHER: non invasive co-oximetry haemaglobin measurement
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparison of the Use of Dexamethasone and Diclofenac Sodium in Immediate Post-Operative Care in Third Molar Surgery
Status: UNKNOWN
Conditions: Impacted Third Molar Tooth
Interventions: DRUG: Dexamethasone|DRUG: Diclofenac Sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Vaccine Schedule With Ad26.Mos.HIV and MVA-Mosaic in Human Immunodeficiency Virus (HIV)-Infected Adults
Status: COMPLETED
Conditions: Human Immunodeficiency Virus
Interventions: BIOLOGICAL: Ad26.Mos.HIV|BIOLOGICAL: MVA-Mosaic|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Breastfeeding Counseling on Social Support Perception, Breastfeeding Self-Efficacy and Outcomes
Status: NOT_YET_RECRUITING
Conditions: Breastfeeding, Exclusive|Nurse's Role|Self Efficacy
Interventions: BEHAVIORAL: Nurse Consultancy Program to Develop Breastfeeding Self-Efficacy Resources
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of the Efficacy and Safety of Quetiapine Fumarate Extended Release (Seroquel XR)
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Quetiapine Fumarate XR
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of AT-527 in Subjects With Moderate Coronavirus Disease (COVID-19) in a Hospital Setting
Status: TERMINATED
Conditions: COVID-19
Interventions: DRUG: AT-527|OTHER: Placebo|DRUG: AT-527|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Carotid Doppler Peak Velocity Variation in Liposuction Fluid Management
Status: RECRUITING
Conditions: Lipodystrophy
Interventions: OTHER: Intraoperative fluid ratio|DEVICE: Carotid Artery Doppler Peak Velocity Variation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of M2951 in Participants With Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Placebo|DRUG: M2951|DRUG: M2951
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Acitretin Versus Narrowband Ultraviolet B on Neopterin Level in Psoriatic Patients .
Status: UNKNOWN
Conditions: Psoriasis
Interventions: DRUG: Acitretin 25Mg Cap|RADIATION: Narrowband ultraviolet B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Two Dose Levels of AZD2115 in Subjects With Moderate to Severe COPD
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: DRUG: AZD2115 Dose 1|DRUG: AZD 2115, Dose 2|DRUG: Placebo MDI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Multicenter，Double-Blind and Randomized Controlled Trial of Fengshigutong Capsule in the Treatment of Ankylosing Spondylitis
Status: UNKNOWN
Conditions: Ankylosing Spondylitis
Interventions: DRUG: Fengshigutong Capsule plus Imrecoxib|DRUG: Fengshigutong Capsule|DRUG: Imrecoxib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Tislelizumab in Combination With Disitamab-vedotin as Neoadjuvant Therapy for HER2-positive High-risk Upper Tract Urothelial Carcinoma (UTUC)
Status: RECRUITING
Conditions: Neoadjuvant Immunotherapy
Interventions: DRUG: tislelizumab+disitamab-vedotin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Molecular Imaging Study of Harmine/DMT: a Basic Research Approach
Status: RECRUITING
Conditions: Neuropharmacological Investigation of Ayahuasca Constituents DMT and Harmine
Interventions: DRUG: N,N-dimethyltryptamine (DMT) + harmine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy of Centervention-ATOD: An Implementation Tool for Dissemination of Evidence-based Programs for Substance Abuse
Status: COMPLETED
Conditions: Substance Abuse
Interventions: OTHER: Centervention-ATOD (CV-ATOD)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Endometrial Biopsy Protocol for In Vitro Fertilization (IVF)
Status: UNKNOWN
Conditions: Infertility|Recurrent Implantation Failure
Interventions: PROCEDURE: endometrial biopsy/ies
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Adherence and Therapeutic Effectiveness of Bi-Flex Versus CPAP in Children With OSA
Status: COMPLETED
Conditions: Obstructive Sleep Apnea
Interventions: DEVICE: Bi-Flex|DEVICE: CPAP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Autologous Adipose Tissue-Derived Mesenchymal Stem Cells (AdMSCs) for Osteoarthritis
Status: NOT_YET_RECRUITING
Conditions: Osteoarthritis, Knee|Osteoarthritis, Hip|Osteoarthritis Shoulder
Interventions: BIOLOGICAL: Celltex- AdMSCs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ventilator Aspiration With PneuX (PneuX vs Standard Care Feasibility RCT)
Status: RECRUITING
Conditions: Ventilator Associated Pneumonia|Aspiration|Infections|Ventilator Lung
Interventions: DEVICE: PneuX Endotracheal Tube|DEVICE: Standard care (Taperguard, Covidien)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Timing of Coronary Angiography in NSTE-ACS With ADHF
Status: TERMINATED
Conditions: Heart Failure|Acute Coronary Syndrome
Interventions: PROCEDURE: Immediate coronary angiography within 2 hours after randomization|PROCEDURE: Delayed coronary angiography after stabilization of heart failure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Safety, Tolerability and Efficacy of iNexin™ for the Treatment of the Signs and Symptoms Associated With Dry Eye Disease
Status: COMPLETED
Conditions: Dry Eye Disease
Interventions: DRUG: iNexin™ (0.08% aCT1)|DRUG: iNexin™ (0.4% aCT1)|DRUG: iNexin™ (2.0% aCT1)|DRUG: Vehicle (eye drop formulation without aCT1)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing 3 Schedules of Alimta Plus Gemzar
Status: COMPLETED
Conditions: Carcinoma, Non-Small-Cell Lung|Lung Neoplasms|Neoplasms
Interventions: DRUG: Pemetrexed (Alimta) in combination with gemcitabine (Gemzar)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Maintenance Infusion of Oxytocin Following Elective Cesarean Deliveries
Status: COMPLETED
Conditions: Postpartum Hemorrhage
Interventions: DRUG: Oxytocin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PIPAC With Nab-paclitaxel and Cisplatin in Peritoneal Carcinomatosis
Status: ACTIVE_NOT_RECRUITING
Conditions: Peritoneal Carcinomatosis
Interventions: DRUG: Nab paclitaxel|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transcranial Direct Current Stimulation vs Pilates Core Training in Stroke
Status: RECRUITING
Conditions: Stroke|Cerebrovascular Accident
Interventions: DEVICE: transcranial direct current stimulation|OTHER: Pilates based core training|OTHER: conventional physiotherapy program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Prednisolone or Dexamethasone Combined With Chemotherapy in Treating Young Patients With Newly Diagnosed Lymphoblastic Lymphoma
Status: TERMINATED
Conditions: Lymphoma
Interventions: DRUG: asparaginase|DRUG: cyclophosphamide|DRUG: cytarabine|DRUG: daunorubicin hydrochloride|DRUG: dexamethasone|DRUG: doxorubicin hydrochloride|DRUG: leucovorin calcium|DRUG: mercaptopurine|DRUG: methotrexate|DRUG: prednisolone|DRUG: thioguanine|DRUG: vincristine sulfate|PROCEDURE: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: "Twelve-week Study of the Safety and Efficacy of JZP-110 in the Treatment of Excessive Sleepiness in OSA"
Status: COMPLETED
Conditions: Obstructive Sleep Apnea
Interventions: DRUG: JZP-110|DRUG: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Adrenal Insufficiency in Cirrhotics With Ascites. Effects of Hydrocortisone on Renal and Haemodynamic Function
Status: UNKNOWN
Conditions: Cirrhosis With Ascites
Interventions: DRUG: hydrocortisone|DRUG: dextrose solution 5%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Correlation Between the Analysis of the Rapid Cortical Oscillations, the General Movements of the Preterm's and the Cerebral Palsy
Status: COMPLETED
Conditions: Cerebral Palsy
Interventions: OTHER: Electroencephalogram, recording the movements
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Using ICT to Deliver Brief Motivational Interviewing to Promote Smoking Cessation Among Smokers With Chronic Diseases
Status: UNKNOWN
Conditions: Smoking Cessation
Interventions: BEHAVIORAL: Motivational Interviewing (i-BMI)|BEHAVIORAL: Individual face-to-face generic health advice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Group Parent Training for Adolescent Eating Disorders
Status: COMPLETED
Conditions: Adolescent Anorexia Nervosa|Subthreshold Anorexia Nervosa
Interventions: BEHAVIORAL: Group Parent Training|BEHAVIORAL: Maudsley Family Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing Ensatinib Versus Platinum-Based Chemotherapy as Adjuvant Treatment for Stage II-IIIA ALK -Positive Non-Small Cell Lung Cancer
Status: NOT_YET_RECRUITING
Conditions: ALK Fusion Protein Expression|Adjuvant Therapy|Non-Small Cell Lung Cancer
Interventions: DRUG: Ensatinib|DRUG: chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Disulfiram Interactions With HIV Medications: Clinical Implications
Status: COMPLETED
Conditions: HIV Infections|Drug Abuse
Interventions: DRUG: Disulfiram|DRUG: Disulfiram + Efavirenz|DRUG: Disulfiram + Atazanavir|DRUG: Disulfiram + Ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: VNRX-5024 Safety and PK in Healthy Adult Volunteers
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: VNRX-5024|DRUG: Placebo for VNRX-5024
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Peas in Muffins on Blood Glucose and Appetite Control
Status: ACTIVE_NOT_RECRUITING
Conditions: Post-prandial Glycaemic Response|Satiety
Interventions: DIETARY_SUPPLEMENT: Whole pea muffins|DIETARY_SUPPLEMENT: Split pea muffins|DIETARY_SUPPLEMENT: Wheat muffins
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Thymosin Alpha 1 in the Prevention of Pancreatic Infection Following Acute Necrotizing Pancreatitis
Status: COMPLETED
Conditions: Pancreatitis, Acute Necrotizing
Interventions: DRUG: Thymosin Alpha 1|DRUG: normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics, and Clinical Activity of JNJ-63723283, an Anti-PD-1 Monoclonal Antibody, in Participants With Advanced Cancers
Status: ACTIVE_NOT_RECRUITING
Conditions: Neoplasms
Interventions: DRUG: JNJ-63723283
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Two-Part Study to Evaluate the Efficacy, Safety, Tolerability and Pharmacokinetics of Repeat Doses of Inhaled ETD001 in People With Cystic Fibrosis
Status: RECRUITING
Conditions: Cystic Fibrosis
Interventions: DRUG: ETD001|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: AutoLogous Human CArdiac-Derived Stem Cell to Treat Ischemic cArdiomyopathy (ALCADIA)
Status: COMPLETED
Conditions: Congestive Heart Failure|Ischemic Cardiomyopathy|Ventricular Dysfunction
Interventions: PROCEDURE: human cardiac stem cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pegylated Interferon Plus Ribavirin in the Treatment of Active and Past Intravenous Drug Users Infected With Hepatitis C
Status: COMPLETED
Conditions: Hepatitis c
Interventions: DRUG: pegylated interferon alfa-2a ( Roche) and ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Ketogenic Potential of Different Diet Supplements
Status: COMPLETED
Conditions: Healthy Adults
Interventions: DIETARY_SUPPLEMENT: Control|DIETARY_SUPPLEMENT: Leucine|DIETARY_SUPPLEMENT: Butyrate -|DIETARY_SUPPLEMENT: Butyrate +|DIETARY_SUPPLEMENT: Octanoate -|DIETARY_SUPPLEMENT: Octanoate +|DIETARY_SUPPLEMENT: Carnitine|DIETARY_SUPPLEMENT: Butter fraction
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Monitoring OXYgen in Infants Hospitalized With Bronchiolitis: A Best Practices Trial (The MOXY Trial)
Status: COMPLETED
Conditions: Bronchiolitis
Interventions: PROCEDURE: Intermittent oxygen monitoring|PROCEDURE: Continuous oxygen monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy of Laparoscopic Sleeve Gastrectomy and Intensive Medical Management in Obese Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus|Obesity
Interventions: PROCEDURE: Sleeve gastrectomy|DRUG: Intensive medical management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single Oral Dose of Dexamethasone Versus Five Days of Prednisone in Adult Asthma
Status: COMPLETED
Conditions: Asthma|Reactive Airway Disease
Interventions: DRUG: Dexamethasone|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Intranasal Oxytocin on Functional Brain Network in Resting-state and Tasks
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Oxytocin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Influence of Probenecid and Quinine on the Pharmacokinetics of Azidothymidine
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Quinine sulfate|DRUG: Probenecid|DRUG: Zidovudine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Efficacy of Different Steroids in the Treatment of Abnormal Scars (Keloids, Hypertrophic Scars)
Status: UNKNOWN
Conditions: Keloid|Hypertrophic Scar|Scars|Scarring
Interventions: DRUG: Betamethasone acetate + Betamethasone sodium phosphate|DRUG: Dexamethasone sodium phosphate|DRUG: Methylprednisolone acetate|DRUG: Triamcinolone acetonide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT