pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Emollient Therapy for Severe Acute Malnutrition
Status: COMPLETED
Conditions: Child Malnutrition|Malnutrition in Children|Malnutrition
Interventions: OTHER: Topical emollient (Sun Flower seed oil)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase III Randomized Study of 5-FU, CoFactor, and Avastin vs. 5-FU, LV and Avastin for First-Line Colorectal Cancer.
Status: UNKNOWN
Conditions: Metastatic Colorectal Cancer|Colon Cancer|Rectal Cancer
Interventions: DRUG: 5- Fluorouracil (5-FU)|DRUG: bevacizumab (Avastin)|DRUG: Leucovorin|DRUG: CoFactor (ANX-510)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase-I Study of Radiolabeled DFH-12 (PulmoBind) for Molecular Imaging of the Pulmonary Circulation
Status: COMPLETED
Conditions: Pulmonary Disease|Pulmonary Hypertension
Interventions: RADIATION: 99mTC-PulmoBind
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Labial Alveolar Bone Thickness and Apical Root Resorption Changes Associated With Self-ligating Versus Conventional Brackets
Status: UNKNOWN
Conditions: Labial Alveolar Bone Thickness|Apical Root Resorption
Interventions: DEVICE: Clarity SL MBT brackets; 3M Unitek, Monrovia, CA, USA|DEVICE: Gemini MBT brackets; 3M Unitek, Monrovia, CA, USA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Analysis of the Relationship Between the Quantitative Index of Cytokines in the Oral Fluid and Inflammation
Status: RECRUITING
Conditions: Chronic Inflammation
Interventions: DIAGNOSTIC_TEST: test for quantitative index of interleukins in the oral fluid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Feasibility Study of N-acetylcysteine for Self-injurious Behavior in Children With Autism Spectrum Disorder
Status: COMPLETED
Conditions: Autism Spectrum Disorder
Interventions: DRUG: N-acetylcysteine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of Diet, Physical Activity and Breast Cancer Recurrences: the DIANA-5 Study
Status: COMPLETED
Conditions: Breast Cancer Invasive
Interventions: BEHAVIORAL: Intervention group on diet and physical activity|BEHAVIORAL: Control group: only public recommendation an lifestyle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Care Package on Duration of Stay and Physiological Parameters in Non-invasive Mechanical Ventilation
Status: COMPLETED
Conditions: Care
Interventions: BEHAVIORAL: The group to which a care package was applied in addition to the clinical routine care protocol)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Gemcitabine & Nab-Paclitaxel in Pancreatic Adenocarcinoma With Positive Peritoneal Cytology
Status: UNKNOWN
Conditions: Pancreatic Adenocarcinoma
Interventions: DRUG: Gemcitabine|DRUG: nab-paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Pharmacokinetics, Pharmacodynamics and Safety Assessment of GNR-044 (JSC GENERIUM, Russia) and Xolair®
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: BIOLOGICAL: Omalizumab (JSC "GENERIUM", the Russian Federation)|BIOLOGICAL: Xolair® (Novartis Pharma AG, Switzerland)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Midodrine for the Early Liberation of Vasopressor Support in the ICU
Status: COMPLETED
Conditions: Critical Illness|Shock
Interventions: DRUG: Midodrine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Whether Functional Strength Training Can Enhance Motor Recovery of the Upper Limb After Stroke
Status: COMPLETED
Conditions: Stroke
Interventions: BEHAVIORAL: Conventional UK physical therapy|BEHAVIORAL: Increased intensity of UK conventional physical therapy (PT)|BEHAVIORAL: UK conventional PT plus functional strength training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Arachidonic Acid Treatment Against Schistosomiasis Infection in Children
Status: COMPLETED
Conditions: Schistosomiasis|Bilharzia
Interventions: DRUG: Praziquantel (PZQ)|DIETARY_SUPPLEMENT: Arachidonic acid (ARA)|DIETARY_SUPPLEMENT: PZQ+ARA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Optimized Complementary Feeding With or Without Home Fortification Prevents Decrease of Micronutrient and Growth
Status: COMPLETED
Conditions: Complementary Feeding|Linear Programming|Nutritional Status|Micronutrient Deficiency|Growth Failure
Interventions: BEHAVIORAL: Nutritional education program|DIETARY_SUPPLEMENT: Home fortification (Taburia)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Pranayama Practice on the Autonomic Nervous System
Status: COMPLETED
Conditions: Pranayama Effect on Autonomic Nervous System|Respiration Variability Effect on Nervous System
Interventions: OTHER: Sheetali/Sheekari Pranayama|OTHER: Sitting Quietly|OTHER: Deep breathing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluating Alternative Aftercare Models for Ex-offenders
Status: COMPLETED
Conditions: Drug/Substance Abuse/Addiction|Alcohol Abuse/Addiction
Interventions: BEHAVIORAL: Oxford House|BEHAVIORAL: Safe Haven|BEHAVIORAL: Usual aftercare
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Degenerative Spondylolisthesis on the Clinical Outcome of Unilateral Biportal Endoscopy for Lumbar Spinal Stenosis: Study Protocol
Status: RECRUITING
Conditions: Degenerative Spondylolisthesis|Lumbar Spinal Stenosis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: DECODING Study (Dermal Electrochemical Conductance in Diabetic Neuropathy)
Status: COMPLETED
Conditions: Neuropathy, Diabetic|Diabetes Mellitus, Type 2
Interventions: DIAGNOSTIC_TEST: dermal electrochemical conductance (DEC)|DIAGNOSTIC_TEST: Monofilament testing
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SCREENING
Clinical trial: Ultrasonic Bone Scalpel in BSSO
Status: COMPLETED
Conditions: Maxillofacial Abnormalities
Interventions: DEVICE: Conventional|DEVICE: Bone Scalpel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Wide Area Transepithelial Sample Esophageal Biopsy Combined With Computer Assisted 3-Dimensional Tissue Analysis (WATS3D) For the Detection of High Grade Esophageal Dysplasia and Adenocarcinoma
Status: COMPLETED
Conditions: Barrett Esophagus|Esophageal Dysplasia|Esophageal Adenocarcinoma
Interventions: PROCEDURE: Diagnostic Test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Intensive Neoadjuvant Chemotherapy in Treating Young Patients Undergoing Surgical Resection for High-Risk Hepatoblastoma
Status: UNKNOWN
Conditions: Liver Cancer
Interventions: DRUG: carboplatin|DRUG: cisplatin|DRUG: doxorubicin hydrochloride|PROCEDURE: adjuvant therapy|PROCEDURE: conventional surgery|PROCEDURE: neoadjuvant therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Febuxostat on Joint Damage in Hyperuricemic Subjects With Early Gout
Status: COMPLETED
Conditions: Joint Damage
Interventions: DRUG: Febuxostat|DRUG: Placebo for Febuxostat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Treatment With a Single Dose of 90Y-ibritumomab Tiuxetan in Patients With Low Tumor Burden Untreated or Indolent NHL
Status: WITHDRAWN
Conditions: Lymphoma
Interventions: DRUG: 90Y-ibritumomab tiuxetan (Zevalin)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ketodex Versus Opioid Based Anaesthesia in Cleft Palate Repair Ketodex Versus Opioid Based Anaesthesia in Cleft Palate Repair Ketodex Versus Opioid Based Anaesthesia in Cleft Palate Repair Ketodex Versus Opioids in Cleft Palate Repaire
Status: UNKNOWN
Conditions: Ketodex Versus Opioids Based Anaesthesia in Cleft Palate Repair
Interventions: DRUG: Ketodex, Fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An Efficacy and Safety Study of Itraconazole Sequential Therapy (Intravenous Injection Followed by Oral Solution) in Invasive Pulmonary Fungal Infections
Status: COMPLETED
Conditions: Pulmonary Fungal Infection
Interventions: DRUG: Itraconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Cured Pork Peptides on Blood Pressure & Cardiovascular Risk Factors
Status: UNKNOWN
Conditions: Hypertension|Cardiovascular Diseases
Interventions: OTHER: Spanish cured-pork ham|OTHER: Cooked pork ham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Functional Medicine in Asthma (FAst) Study
Status: COMPLETED
Conditions: Asthma
Interventions: BEHAVIORAL: Lifestyle Factors|OTHER: Customized use of Dietary Supplements|OTHER: Currently Accepted Asthma Care Guidelines
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Study on a Novel Port-site Closure Device (EZ Close): Effectiveness and Comparison With Carter-Thomason
Status: COMPLETED
Conditions: Surgical Port Site Hernia
Interventions: DEVICE: EZ close|DEVICE: Carter Thomason
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Partial Breast Radiation Therapy in Treating Women Undergoing Breast Conservation Therapy for Early-Stage Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer|Long-term Effects Secondary to Cancer Therapy in Adults|Skin Reactions Secondary to Radiation Therapy
Interventions: PROCEDURE: adjuvant therapy|PROCEDURE: conventional surgery|RADIATION: 3-dimensional conformal radiation therapy|RADIATION: brachytherapy|RADIATION: intracavitary balloon brachytherapy|RADIATION: proton beam radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioavailability of Warfarin After Coadministration With Multiple Doses of BI 1356 Compared to the Bioavailability of Warfarin Alone in Healthy Male Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Warfarin|DRUG: BI 1356
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: LIraglutide and Beta-cell RepAir (LIBRA) Study
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: Liraglutide|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Influence of Diabetes Control on Treatment of Diabetic Macular Edema With Ranibizumab
Status: TERMINATED
Conditions: Visual Acuity Reduced Transiently|Macular Edema, Cystoid
Interventions: DRUG: ranibizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Safety of PregSense™ and Compare Its Performance to CTG in Prenatal Monitoring of Pregnant Subjects
Status: COMPLETED
Conditions: Pregnancy
Interventions: DEVICE: PregSense™|DEVICE: Cardiotocopraphy (CTG)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Continuous Lidocaine Infusion Via Closed Chest Drainage Tube for Pain Control After Thoracoscopic Partial Lung Resection
Status: NOT_YET_RECRUITING
Conditions: Lidocaine|Analgesia|Pain, Postoperative|Thoracic Surgery
Interventions: DRUG: Lidocaine|DRUG: normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Sacituzumab Govitecan Before Radical Cystectomy for the Treatment of Non-Urothelial Muscle Invasive Bladder Cancer
Status: RECRUITING
Conditions: Muscle Invasive Bladder Carcinoma|Stage II Bladder Cancer AJCC v8|Stage IIIA Bladder Cancer AJCC v8
Interventions: PROCEDURE: Lymphadenectomy|PROCEDURE: Radical Cystectomy|BIOLOGICAL: Sacituzumab Govitecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low-dose Radiotherapy Plus Tislelizumab in Combination With Afatinib for Neoadjuvant Treatment of Surgically Resectable Head and Neck Squamous Carcinoma
Status: RECRUITING
Conditions: Head and Neck Cancer
Interventions: BIOLOGICAL: Tislelizumab|DRUG: Afatinib|RADIATION: Low dose radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of pDNA Vaccines Expressing HIV M Group p24^Gag Conserved Elements and/or p55^Gag, Administered With IL-12 pDNA
Status: COMPLETED
Conditions: HIV Infections
Interventions: BIOLOGICAL: p24CE1/2 pDNA Vaccine|BIOLOGICAL: p55^gag pDNA Vaccine|BIOLOGICAL: IL-12 pDNA Adjuvant|BIOLOGICAL: Placebo|DEVICE: Ichor Medical Systems Intramuscular TriGrid Delivery System (TDS-IM) electroporation (EP) device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pearlium®/Effecti-Cal®, a Novel Formulation of Calcium, Vitamin D and Minerals for Prevention of Postmenopausal Bone Loss
Status: COMPLETED
Conditions: Osteoporosis, Postmenopausal
Interventions: DRUG: Pearlium/EffectiCal|DRUG: Calcium carbonate/vitamin D3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Milk Secretory Supplement in Breast-feeding Volunteers
Status: RECRUITING
Conditions: Lactation
Interventions: DIETARY_SUPPLEMENT: Milk secretory supplement group|DIETARY_SUPPLEMENT: Placebo group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Immunogenicity of a Human Hookworm Candidate Vaccine With Different Doses of a Novel Adjuvant
Status: COMPLETED
Conditions: Hookworm Infection|Hookworm Disease
Interventions: BIOLOGICAL: 10 μg Na-GST-1/Alhydrogel|BIOLOGICAL: 30 μg Na-GST-1/Alhydrogel|BIOLOGICAL: 100 μg Na-GST-1/Alhydrogel|BIOLOGICAL: 10 μg Na-GST-1/Alhydrogel/GLA-AF (1 μg)|BIOLOGICAL: 30 μg Na-GST-1/Alhydrogel/GLA-AF (1 μg)|BIOLOGICAL: 30 μg Na-GST-1/Alhydrogel/GLA-AF (5 μg)|BIOLOGICAL: 100 μg Na-GST-1/Alhydrogel/GLA-AF (5 μg)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study Investigating the Safety, Tolerability, Drug Levels and Drug Effect of BMS-986278 in Healthy Adult Participants (Part 1) and Japanese Participants (Part 2)
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DRUG: BMS-986278|DRUG: Sildenafil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Glutathione Levels and Compulsivity
Status: COMPLETED
Conditions: Anorexia Nervosa|Compulsive Behavior
Interventions: DRUG: N-acetyl cysteine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Personalised Risk scOre For Implantation of Defibrillators in Patients With Preserved LVEF>35% and a High Risk for Sudden Cardiac Death
Status: WITHDRAWN
Conditions: Myocardial Infarction|Sudden Cardiac Death
Interventions: DRUG: Optimal Medical Therapy (OMT)|DEVICE: Implantable cardioverter-defibrillator (ICD)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Caudal Block for Inguinal Hernioplasty in Children
Status: RECRUITING
Conditions: Postoperative Pain
Interventions: DRUG: Caudal block with levobupivacaine|DRUG: General anesthesia|PROCEDURE: Inguinal hernioplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety, Tolerability, and Blood Pressure Effect of an Oral Dose of Sumatriptan Alone and in Combination With MK-0974 (Telcagepant) in Migraine Patients (0974-026)
Status: COMPLETED
Conditions: Migraine Disorders
Interventions: DRUG: telcagepant potassium|DRUG: sumatriptan|DRUG: sumatriptan placebo|DRUG: telcagepant potassium placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: CARE Initiative: Real-world Emulation of the KEYNOTE-189 Trial [DS4]
Status: COMPLETED
Conditions: Metastatic Non Small Cell Lung Cancer
Interventions: DRUG: Pembrolizumab|DRUG: Pemetrexed|DRUG: Cisplatin|DRUG: Carboplatin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Understanding Cognition, Oxytocin & Pain in Elders
Status: RECRUITING
Conditions: Knee Osteoarthritis|Osteoarthritis
Interventions: DRUG: Oxytocin (OT)|DRUG: Placebo (P)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Partial Irradiation and Sequential vs. Concurrent Chemo Early Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer|Adenocarcinoma of the Breast
Interventions: OTHER: PBI with sequential chemotherapy|OTHER: PBI with concurrent chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Dosing of AMG 827 for Subjects With Inadequately Controlled Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: AMG 827|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Vitamin D3 Supplementation on Antioxidant Enzymes Status in Vitamin D3 Deficient Asthma COPD Overlap (ACO) Patients
Status: UNKNOWN
Conditions: Vitamin D Deficiency
Interventions: DIETARY_SUPPLEMENT: Vitamin D3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to Assess Safety and Efficacy in Participants Age 40 to 55 With Presbyopia (Old Eye) Who Receive AGN-190584 in Both Eyes Twice Daily
Status: COMPLETED
Conditions: Presbyopia
Interventions: DRUG: Pilocarpine HCl|DRUG: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Upper Limb Rehabilitation in First Year After Stroke Using Modern Treatment Strategies - a Single Case Study
Status: UNKNOWN
Conditions: Stroke
Interventions: DEVICE: Repetitive Transcranial Magnetic stimulation|DEVICE: Robot Assisted Therapy|OTHER: Enhanced upper limb therapy programme
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of ME-401 in Subjects With Relapsed or Refractory Indolent B-cell Non-Hodgkin's Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Relapsed or Refractory Indolent B-cell Non-Hodgkin's Lymphoma
Interventions: DRUG: ME-401
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Postprandial Blood Glucose and Insulin Levels Following Consumption of Lentil-containing Food Products
Status: COMPLETED
Conditions: Postprandial Glycemia in Healthy Adults
Interventions: OTHER: Muffin: 25g available carbohydrate from small green lentil|OTHER: Muffin: 25g available carbohydrate from split red lentil|OTHER: Wheat muffin|OTHER: Soup: 25g available carbohydrate from small green lentil|OTHER: Soup: 25g available carbohydrate from split red lentil|OTHER: Potato soup|OTHER: Chili: 25g available carbohydrate from small green lentil|OTHER: Chili: 25g available carbohydrate from split red lentil|OTHER: Rice chili
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study Evaluating Heated Lidocaine/Tetracaine Patch in Patients With Pain Associated With Myofascial Trigger Points
Status: COMPLETED
Conditions: Myofascial Pain Syndromes
Interventions: DRUG: Heated lidocaine/tetracaine patch
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cognitive Training for Cancer Related Cognitive Impairment in Breast Cancer Survivors
Status: RECRUITING
Conditions: Breast Cancer|Cognitive Impairments
Interventions: BEHAVIORAL: Arm 1: Computerized Cognitive Training-Global Stimulation Games|BEHAVIORAL: Arm 2: Computerized Cognitive Training-Neuroplasticity Games
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Bioavailability of Vitamin D in Cod Liver Oil and Multivitamin Tablets in Healthy Subjects in Norway
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Fish oil capsule (specially manufactured for the study)|DIETARY_SUPPLEMENT: Multivitamin tablet of type: Vitaplex ABCD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Evaluation of the Performance of Different Daily Disposable Lens Designs in Habitual Soft Contact Lens Wearers
Status: COMPLETED
Conditions: Myopia
Interventions: DEVICE: stenfilcon A - (Test lens)|DEVICE: kalifilcon A - (Control Lens)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Photobiomodulation Therapy in the Prevention and Management of Chemotherapy-Induced Peripheral Neuropathy
Status: ACTIVE_NOT_RECRUITING
Conditions: Chemotherapy-induced Peripheral Neuropathy
Interventions: DEVICE: Multiwave Locked System® (M6 laser, ASA srl, Arcugnano (VI), Italy)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Anti-platelet + Pembro for H&N Tumors
Status: RECRUITING
Conditions: Head and Neck Cancer
Interventions: DRUG: Pembrolizumab|DRUG: Clopidogrel|DRUG: acetylsalicylic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cyclophosphamide and Celecoxib in Treating Patients With Advanced Cancer
Status: COMPLETED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: celecoxib|DRUG: cyclophosphamide|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Effect of Isocaloric Ketogenic Diet on Physical Performance at High Altitude
Status: COMPLETED
Conditions: Ketogenic Dieting|Altitude Hypoxia|Physical Activity
Interventions: DIETARY_SUPPLEMENT: Isocaloric ketogenic diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Working Inside for Smoking Elimination
Status: UNKNOWN
Conditions: Cigarette Smoking|Tobacco Smoking
Interventions: BEHAVIORAL: Motivational Interviewing/CBT|OTHER: CONcise Tapes Reviewing Obstacles to healthy Living (CONTROL)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exercise Induced Bronchospasm in Children
Status: COMPLETED
Conditions: Exercise Induced Bronchospasm
Interventions: DRUG: montelukast vs pretreatment with albuterol|DRUG: montelukast
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: STENTYS Xposition S in the Treatment of Chronic Total Artery Occlusion
Status: UNKNOWN
Conditions: Chronic Total Occlusion|Coronary Artery Disease
Interventions: DEVICE: Implantation of Stent (PCI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Safety and Efficacy of a New Treatment for Diabetic Macular Edema
Status: COMPLETED
Conditions: Diabetic Macular Edema
Interventions: DRUG: Dexamethasone|OTHER: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Testing Afatinib in Combination With Pembrolizumab in Patients With Squamous Cell Carcinoma of the Lung
Status: COMPLETED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: Afatinib|DRUG: pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of TQ-B3101 in Patients With ROS1-positive Non-Small Cell Lung Cancer (NSCLC)
Status: UNKNOWN
Conditions: ROS1-positive Non-Small Cell Lung Cancer (NSCLC)
Interventions: DRUG: TQ-B3101
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Evaluate the Effect of Raltegravir Intensification (1.200 mg QD) on the Gut Microbiota of Chronically HIV-1 Infected Subject Over Time: THE RAGTIME STUDY
Status: COMPLETED
Conditions: HIV
Interventions: DRUG: Raltegravir|DRUG: Placebo|DRUG: Current ART
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Impact of Preoperative Treatment of Anemia and Iron Deficiency in Cardiac Surgery on Outcome.
Status: COMPLETED
Conditions: Anemia|Iron Deficiency
Interventions: DRUG: Erythropoietin/Ferric carboxymaltose/Vitamin B12/Folic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PTA and Drug Eluting Stents for Infrapopliteal Lesions in Critical Limb Ischemia
Status: UNKNOWN
Conditions: Peripheral Vascular Disease
Interventions: DEVICE: PTA with placement of paclitaxel-eluting stent|DEVICE: PTA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Surgery With HIPEC in Treating Patients With a High Risk of Developing Colorectal Peritoneal Carcinomatosis
Status: COMPLETED
Conditions: Malignant Neoplasm of Large Intestine TNM Staging Primary Tumor (T) T4|Peritoneal Carcinomatosis
Interventions: PROCEDURE: Surgery and Hyperthermic Intraperitoneal Chemotherapy with MMC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 3 Study of Dexpramipexole in ALS
Status: COMPLETED
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DRUG: Dexpramipexole|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Oxybutynin in Paediatric Cystitis
Status: COMPLETED
Conditions: Cystitis
Interventions: DRUG: Oxybutynin|OTHER: "Orasweet" Liquid Placebo|DRUG: Antibiotics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation Direct and Indirect Composite Restoration in Hypomineralization Molars.
Status: COMPLETED
Conditions: Dental Enamel Hypoplasia|Dental Caries
Interventions: OTHER: Direct restoration|OTHER: Indirect restoration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Enzalutamide With Ribociclib in Treating Patients With Metastatic Castrate-Resistant, Chemotherapy Naive Prostate Cancer That Retains Retinoblastoma Expression
Status: COMPLETED
Conditions: Castration-Resistant Prostate Carcinoma|Metastatic Prostate Carcinoma|Prostate Carcinoma Metastatic in the Bone|Stage IV Prostate Cancer AJCC v7
Interventions: DRUG: Enzalutamide|DRUG: Ribociclib|OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacological Study|PROCEDURE: Biospecimen Collection|PROCEDURE: Biopsy|PROCEDURE: Echocardiography|PROCEDURE: Multigated Acquisition Scan|PROCEDURE: Bone Scan|PROCEDURE: Computed Tomography|PROCEDURE: Magnetic Resonance Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neo-adjuvant Pembrolizumab in dMMR/ POLE-EDM Uterine Cancer Patients: a Feasibility Study
Status: COMPLETED
Conditions: Uterine Cancer
Interventions: DRUG: Pembrolizumab (Keytruda)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Effects of CY6463 in Participants With Alzheimer's Disease With Vascular Pathology
Status: TERMINATED
Conditions: Alzheimer's Disease With Vascular Pathology
Interventions: DRUG: CY6463|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Double-blind Study to Investigate Efficacy and Safety of Buntanetap Compared With Placebo in Participants With Early PD
Status: COMPLETED
Conditions: Parkinson's Disease, Idiopathic
Interventions: DRUG: buntanetap/posiphen|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Study of Bramitob® Administered for Inhalation by PARI eFlow® vs PARI LC® PLUS Nebulizer
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: Bramitob® administered by PARI LC® PLUS nebulizer|DRUG: Bramitob® administered by PARI eFlow® rapid electronic nebulizer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of the Dietary Food Supplement ALCOFILTRUM in Alleviating Alcohol Hangover Symptoms
Status: RECRUITING
Conditions: Alcohol Drinking|Alcohol Intoxication
Interventions: DIETARY_SUPPLEMENT: ALCOFILTRUM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Trial to Reduce Alloimmunization to Platelets (TRAP)
Status: COMPLETED
Conditions: Blood Platelets|Hematologic Diseases|Immunization|Leukemia, Myelocytic, Acute|Blood Transfusion
Interventions: PROCEDURE: platelet transfusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Bempegaldesleukin and Pembrolizumab With or Without Chemotherapy in Locally Advanced or Metastatic Solid Tumors
Status: TERMINATED
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: NKTR-214|DRUG: Pembrolizumab|DRUG: NKTR-214|DRUG: NKTR-214|DRUG: Cisplatin|DRUG: Carboplatin|DRUG: Nab paclitaxel|DRUG: Paclitaxel|DRUG: Pemetrexed|DRUG: Atezolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mobile Health Technology to Promote Physical Activity in Persons With Parkinson Disease
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: BEHAVIORAL: Mobile Health Technology|BEHAVIORAL: Stretching & Strengthening Exercises|BEHAVIORAL: Walking with Pedometer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Psychiatry and Individual Liberties: a Study of Institutions Characterized by a Reduced Use of Coercion
Status: RECRUITING
Conditions: Psychiatric Hospitalization
Interventions: BEHAVIORAL: Individual and collective semi-structured interviews|BEHAVIORAL: Individual semi-structured interviews with ex-patients|BEHAVIORAL: Observations out in the services
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Deferiprone Extended Release Tablets and Ferriprox Immediate Release Tablets in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Deferiprone extended release|DRUG: Deferiprone immediate release
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Efficacy and Safety of Minodronate in Patients With Low Back Pain
Status: NOT_YET_RECRUITING
Conditions: Postmenopausal Osteoporosis
Interventions: DRUG: Minodronate|DRUG: Alendronate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Altruistically Framed Messages and Impact on Parents' Reported Willingness to Immunize Their Children
Status: COMPLETED
Conditions: Parental Vaccine Intentions for Their Children
Interventions: BEHAVIORAL: Benefits to Child|BEHAVIORAL: Benefits to Society|BEHAVIORAL: Benefits to Child and Society|BEHAVIORAL: CDC VIS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Managing Our Relationship With Food and Eating
Status: COMPLETED
Conditions: Mental Health Wellness 1|Eating Behavior|Stress, Psychological|Eating Habit
Interventions: BEHAVIORAL: Trauma Informed Yoga|BEHAVIORAL: Trauma Informed Psychotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bipolar Radiofrequency Ablation -Role in Prevention of Postoperative Atrial Fibrillation
Status: COMPLETED
Conditions: Postoperative Atrial Fibrillation
Interventions: PROCEDURE: Isolation of pulmonary veins with Bipolar radiofrequency ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Corticosteroids+5-aminosalicylic Acid Compared to Corticosteroids in the Treatment of Moderate-severe Ulcerative Colitis
Status: COMPLETED
Conditions: Ulcerative Colitis
Interventions: DRUG: oral 5-ASA+/-topical 5-ASA+IV corticosteroids / PO Methylprednisolone|DRUG: corticosteroids only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy w/wo WeiLeShu in Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Microbial Colonization|Colorectal Cancer
Interventions: DRUG: Weileshu|DRUG: Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Targeted Therapy vs. Chemotherapy in Patients With Thyroid Cancer
Status: NOT_YET_RECRUITING
Conditions: Refractory Differentiated Thyroid Gland Carcinoma
Interventions: PROCEDURE: Biospecimen Collection|DRUG: Cabozantinib|PROCEDURE: Computed Tomography|DRUG: Dabrafenib|PROCEDURE: Magnetic Resonance Imaging|OTHER: Questionnaire Administration|DRUG: Trametinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial of Doxorubicin/Cyclophosphamide (AC), Docetaxel (D), and Alternating AC and D for Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer|Neoplasm Metastasis
Interventions: DRUG: AC (ADM 40mg/m2+CPA 500mg/m2) q21 days x 6 cycles|DRUG: Docetaxel 60mg/m2 every 21 days for 6 cycles|DRUG: AC and Docetaxel 60mg/m2 alternately q21 days for 6 cycles
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of Early Intervention to Correct the Position of PDC:s
Status: RECRUITING
Conditions: Ectopic Tooth Eruption|Palatal Expansion Technique|Randomized Clinical Trial
Interventions: PROCEDURE: Extraction of the primary canine teeth|PROCEDURE: Expansion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of rhDNase on Ventilation Inhomogeneity in Patients With Cystic Fibrosis
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: rhDNAse|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Loestrin 24(24 Days of "Real" Pills) Fe Versus Loestrin 1/20 (21 "Real" Pills)
Status: COMPLETED
Conditions: Pelvic Pain|Headaches|Emotional
Interventions: DRUG: loestrin 24/4 vs loestrin 1/20|DRUG: loestrin 1/20
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Physiotherapy Treatment With Capacitive Resistive Monopolar Radiofrecuency in Young Women With Dyspareunia
Status: COMPLETED
Conditions: Dyspareunia; Female
Interventions: PROCEDURE: Physical therapy modalities on pelvic floor (manual therapy)|DEVICE: CRMRF|DEVICE: Sham CRMRF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Hed-O-Shift: Hedonic and Neurocognitive Processes in Relation to Dietary Habits and Weight Status
Status: COMPLETED
Conditions: Neurocognitive Correlates of Eating Habits
Interventions: OTHER: First Visit|OTHER: on-line questionnaires|DEVICE: fMRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Investigating the Effect of Pulsatile Administration of Oxytocin on the Desensitization of Human Myometrium In-vitro
Status: COMPLETED
Conditions: Postpartum Hemorrhage
Interventions: DRUG: Oxytocin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SmartCare Driven Pressure Support-Non Invasive Ventilation Feasibility Study
Status: TERMINATED
Conditions: Acute Respiratory Failure
Interventions: DEVICE: SmartCare/PS-NIV Drägerwerk Lübeck Germany
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Tocilizumab (RoActemra/Actemra) in Patients With Ankylosing Spondylitis Who Have Had an Inadequate Response to Previous Tumor Necrosis Factor (TNF) Antagonist Therapy
Status: TERMINATED
Conditions: Spondylitis, Ankylosing
Interventions: DRUG: Tocilizumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Administration of RoActemra/Actemra (Tocilizumab) by Auto-injector Vs. Pre-filled Syringe in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: tocilizumab [RoActemra/Actemra] Syringe|DRUG: tocilizumab [RoActemra/Actemra] auto-injector
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Idelalisib+Obinutuzumab in Patients With Relapsed/Refractory Follicular Lymphoma
Status: TERMINATED
Conditions: Follicular Lymphoma
Interventions: DRUG: Idelalisib|DRUG: Obinutuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nitazoxanide Plus Ribavirin and Peginterferon for Therapy of Treatment Naive HCV Genotype 1 and HIV Coinfected Subjects
Status: COMPLETED
Conditions: HIV Infection|Hepatitis C Infection
Interventions: DRUG: Nitazoxanide (NTZ)|DRUG: Pegylated interferon alfa-2a (PEG)|DRUG: Ribavirin (RBV)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of RO4602522 in Patients With Alzheimer Disease and in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteer, Alzheimer's Disease
Interventions: DRUG: 11C-L-deprenyl-D2|DRUG: RO4602522|DRUG: RO4602522
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Computerized Screening and Brief Physician Advice to Reduce Teen Drinking
Status: WITHDRAWN
Conditions: Alcohol Abuse|Risk Behavior
Interventions: BEHAVIORAL: Computerized screening and brief physician advice|BEHAVIORAL: Computerized SBA with technological extenders
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: The Value of Laparoscopic Ultrasound in Patients Undergoing Laparoscopic Resection for Cancer of the Colon or Rectum
Status: COMPLETED
Conditions: Colon Cancer|Rectum Cancer|Liver Metastases
Interventions: DEVICE: Lap+Lus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Impact of Whey Protein Supplementation on Body Weight and Metabolic Parameters of Bariatric Patients
Status: COMPLETED
Conditions: Bariatric Surgery|Sarcopenia
Interventions: DIETARY_SUPPLEMENT: Maltodextrin|DIETARY_SUPPLEMENT: Whey
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Femoral Nerve Block Versus Adductor Canal Nerve Block for Peri-Operative Analgesia Following Anterior Cruciate Ligament (ACL) Reconstruction: Evaluation of Post-operative Pain and Strength
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Marcaine 0.25 % Injectable Solution|DRUG: Marcaine 0.25 % Injectable Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Exercise Therapy in Patients With Peripheral Artery Disease: Evaluating the Clinical Effectiveness of Exercise Therapy and Exploring Determinants of Improvement
Status: COMPLETED
Conditions: Peripheral Arterial Disease
Interventions: OTHER: Walking|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multiple Dose Study Of PF-05231023 In Obese Adult Subjects
Status: TERMINATED
Conditions: Type 2 Diabetes Mellitus (T2DM)
Interventions: OTHER: Placebo|DRUG: 100 mg PF-05231023
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: INBONE Total Ankle Arthroplasty(TAA)Using Calcaneal Stem Fixation
Status: TERMINATED
Conditions: Arthrodesis|Degenerative Arthritis|Rheumatoid Arthritis|Complications; Arthroplasty, Mechanical
Interventions: DEVICE: Radiographic evaluation of previously implanted patients
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study to Evaluate the Pharmacokinetics, Pharmacodynamics and Safety, of EXPAREL Administered as Sciatic Nerve Block (In Popliteal Fossa), for Postsurgical Analgesia in Subjects Undergoing Bunionectomy
Status: COMPLETED
Conditions: Bunion
Interventions: DRUG: Exparel Injectable Product|DRUG: Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EXCEL Clinical Trial (Universal Registry)
Status: COMPLETED
Conditions: Chronic Coronary Occlusion|Left Main Coronary Artery Disease|Stent Thrombosis|Vascular Disease|Myocardial Ischemia|Coronary Artery Stenosis|Coronary Disease|Coronary Artery Disease|Coronary Restenosis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p