pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Study To Observe The Performance Of A Tablet Form Of PF-04531083 As Evidenced By The Concentration Of PF-04531083 In The Blood With Time Following Oral Administration To Healthy Volunteers.
Status: COMPLETED
Conditions: Chronic Pain
Interventions: DRUG: PF-04531083|DRUG: PF-04531083
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A 6-Week Study Of PF-05175157 In Type 2 Diabetes Mellitus
Status: TERMINATED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: PF-05175157|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Different Dosage of Domestic and Imported Clopidogrel on the Platelet Inhibition Ratio in Patients Undergoing PCI
Status: UNKNOWN
Conditions: Coronary Heart Disease
Interventions: DRUG: Clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Sutureless Devices for PICC and a New System KT FIX PLUS
Status: UNKNOWN
Conditions: Catheter Complications|Thrombosis|Displacement of Infusion Catheter|Quality of Life
Interventions: DEVICE: KTFIX PLUS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of Recombinant Von Willebrand Factor (rVWF) in Pediatric and Adult Participants With Severe Von Willebrand Disease (VWD)
Status: RECRUITING
Conditions: Von Willebrand Disease (VWD)
Interventions: BIOLOGICAL: rVWF|BIOLOGICAL: rFVIII
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Phase 1 Trial of AZD6422 in CLDN18.2+ GI Tumors
Status: RECRUITING
Conditions: Gastrointestinal Tumors
Interventions: BIOLOGICAL: AZD6422 CLDN18.2 CAR-T product
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Biomarkers in Tumor Tissue Samples From Patients With Stage III, Stage IV, or Recurrent Endometrial Cancer
Status: COMPLETED
Conditions: Recurrent Uterine Corpus Carcinoma|Stage III Uterine Corpus Cancer|Stage IV Uterine Corpus Cancer
Interventions: OTHER: Laboratory Biomarker Analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Enhancing Modulation Effects of Baduanjin Through Neuromodulation for Knee OA
Status: RECRUITING
Conditions: Knee Osteoarthritis
Interventions: BEHAVIORAL: BDJ|DEVICE: tDCS|DEVICE: sham tDCS|OTHER: exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Bioavailability Study Comparing 3 Different AZD1981 Tablets
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: AZD1981, current small-particle tablet|DRUG: AZD1981, new small-particle tablet|DRUG: AZD1981, new large-particle table
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Safety of Acoramidis (AG10) in Subjects With Transthyretin Amyloid Polyneurophathy (ATTRibute-PN)
Status: WITHDRAWN
Conditions: Transthyretin-Related (ATTR) Familial Amyloid Polyneuropathy
Interventions: DRUG: Acoramidis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Efficacy and Safety of 4 Doses of Imeglimin After 24 Weeks of Treatment in Subjects With Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Imeglimin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cold Induced Activation of Brown Adipose Tissue in Humans
Status: COMPLETED
Conditions: Adipose Tissue, Brown|Brown Adipose Tissue|Brown Fat|Uncoupling Protein 1|Adipokines|Proteomics|Infrared Thermography|BAT|Obesity|Type 2 Diabetes|Proteins
Interventions: PROCEDURE: Cooling|PROCEDURE: Thermoneutral
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety, Tolerability and Pharmacokinetics (PK) Investigation of GSK3494245 in Healthy Participants
Status: COMPLETED
Conditions: Leishmaniasis
Interventions: DRUG: GSK3494245|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Uterine Fibroids With Magnetic Resonance Guided High Intensity Focused Ultrasound
Status: WITHDRAWN
Conditions: Uterine Leiomyoma
Interventions: DEVICE: Magnetic Resonance Guided High Intensity Focused Ultrasound|DRUG: leuprolide acetate for depot suspension
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy Study of Sodium Hyaluronate to Treat Symptomatic Hip Osteoarthritis
Status: TERMINATED
Conditions: Symptomatic Hip Osteoarthritis
Interventions: DRUG: Sodium hyaluronate|DRUG: placebo injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The KinematX Midcarpal Total Wrist Arthroplasty Registry
Status: RECRUITING
Conditions: Scapholunate Advanced Collapse (SLAC)|Scapholunate Crystalline Advanced Collapse (SCAC)|Scaphoid, Trapezium, and Trapezoid Advanced Collapse (STTAC)|Carpal Tunnel Syndrome (CTS)|Kienbock's Disease of Adults|Radial Malunion|Ulnar Translocation|Post Traumatic Arthritis|Inflammatory Arthritis|Osteoarthritis|Scaphoid Non-union Advanced Collapse (SNAC)
Interventions: DEVICE: KinematX total wrist arthroplasty system
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Thalidomide for the Treatment of Hormone-Dependent Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: Thalidomide|DRUG: leuprolide acetate|DRUG: goserelin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Telmisartan Between T80/A5/H12.5 mg FDC Tablet and T80/A5 mg Tab and H12.5 mg Tab Concomitant Use
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: T80/A5 mg FDC tablet|DRUG: T80/A5 mg FDC tablet|DRUG: H12.5 mg tablet|DRUG: T80/A5/H12.5 ng FDC tablet|DRUG: H12.5 mf tablet|DRUG: T80/A5/H12.5 mg FDC tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Asynchronous Mindfulness Based Stress Reduction to Reduce Burnout in Licensed Clinical Social Workers
Status: COMPLETED
Conditions: Burnout, Professional|Work Related Stress|Quality of Life
Interventions: BEHAVIORAL: Mindfulness Based Stress Reduction (MBSR)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Eus-guided Cryothermal Ablation in Stage III Pancreatic Adenocarcinoma
Status: WITHDRAWN
Conditions: Pancreatic Adenocarcinoma|Pancreatic Cancer|Pancreas Neoplasm
Interventions: DEVICE: HTP treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility, Acceptability, and Safety of Neonatal Male Circumcision in Lusaka, Zambia
Status: COMPLETED
Conditions: Neonatal Male Circumcision
Interventions: PROCEDURE: Neonatal male circumcision
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: RISK ANALYSIS AND MANAGEMENT FOR MEDICATION OPTIMIZATION IN THE PREOPERATIVE AND POSTOPERATIVE PERIOD OF CARDIAC SURGICAL PATIENTS
Status: COMPLETED
Conditions: Drug Related Problems|Clinical Pharmacy|Cardiac Surgery|Risk Assesment
Interventions: OTHER: Clinical pharmacist's recommendation to physicians about drug related problems
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Alimta and Gemcitabine in Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer|Stage IIIB or IV
Interventions: DRUG: gemcitabine plus pemetrexed, paclitaxel plus gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Excimer Light Treatment for Idiopathic Guttate Hypomelanosis: A Pilot Study
Status: COMPLETED
Conditions: Idiopathic Guttate Hypomelanosis
Interventions: DEVICE: Excimer Light Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Diagnosis of Arrhythmias in Syncope by Pocket-ECG III® or Conventional Holter
Status: COMPLETED
Conditions: Syncope
Interventions: DEVICE: Pocket-ECG III system
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect and Safety of Liraglutide 3.0 mg as an Adjunct to Intensive Behaviour Therapy for Obesity in a Non-specialist Setting
Status: COMPLETED
Conditions: Metabolism and Nutrition Disorder|Obesity
Interventions: DRUG: liraglutide|DRUG: placebo|BEHAVIORAL: CMS Intensive Behavior Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of Essential Amino Acid Supplementation in Protein Deficient Patients Following Total Knee Arthroplasty
Status: TERMINATED
Conditions: Quad Atrophy
Interventions: DRUG: Amino Acid|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics and Tolerability of Vortioxetine (Lu AA21004) in Child and Adolescent Patients With Depressive or Anxiety Disorder
Status: COMPLETED
Conditions: Depressive Disorder|Anxiety Disorder
Interventions: DRUG: Vortioxetine|DRUG: Vortioxetine|DRUG: Vortioxetine|DRUG: Vortioxetine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Wet Heparinized Suction for Abdominal Cancer
Status: NOT_YET_RECRUITING
Conditions: Cancer of Pancreas|Cancer of Stomach|Cancer of Esophagus|Cancer of Liver|Cancer
Interventions: OTHER: wet heparinzed suction|OTHER: Microsieve|OTHER: No heparin flush|OTHER: No microsieve
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Multimedia Educational Program for Patients With Early-Stage Prostate Cancer or Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer|Depression|Long-term Effects of Cancer Treatment|Prostate Cancer|Psychosocial Effects of Cancer and Its Treatment
Interventions: OTHER: educational intervention|OTHER: informational intervention|OTHER: internet-based intervention|OTHER: questionnaire administration|OTHER: study of socioeconomic and demographic variables|OTHER: survey administration|PROCEDURE: psychosocial assessment and care|PROCEDURE: quality-of-life assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: TETRAGRIP II - Usability Trial of an FES Orthosis for People With Tetraplegia.
Status: COMPLETED
Conditions: Spinal Cord Injuries|Tetraplegia
Interventions: DEVICE: TetraGrip II system
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Safety and Efficacy Extension Study of Pertuzumab in Patients With Solid Tumors Previously Enrolled in a Hoffmann-La Roche-Sponsored Pertuzumab Clinical Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Solid Tumor
Interventions: DRUG: Pertuzumab|DRUG: Trastuzumab|DRUG: Other Combination Anti-Cancer Therapies
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Erlotinib Re-Challenge for Recurrent EGFR-mutant Lung Cancer in Patients Who Previously Received Adjuvant Erlotinib or Gefitinib
Status: TERMINATED
Conditions: Lung Cancer
Interventions: DRUG: erlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Open-label Extension Study With Flexible Dosing of Extended-release (ER) Tapentadol (CG5503) to Treat Patients With Moderate to Severe Chronic Pain
Status: COMPLETED
Conditions: Pain|Osteoarthritis|Low Back Pain
Interventions: DRUG: Tapentadol (CG5503) Extended Release (ER)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Different Doses of BI 1467335 Compared to Placebo in Patients With Clinical Evidence of NASH
Status: COMPLETED
Conditions: Non-alcoholic Fatty Liver Disease
Interventions: DRUG: BI 1467335|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: PD-1 Inhibitor Plus G-CSF in Recurrent/Metastatic NPC With First-line Treatment Failure
Status: UNKNOWN
Conditions: PD-1 Inhibitor|G-CSF
Interventions: DRUG: Camrelizumab|DRUG: G-CSF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Imaging of Solid Tumors Using FAP-2286
Status: RECRUITING
Conditions: Solid Tumors, Adult|Metastatic Cancer
Interventions: DRUG: Gallium-68 labelled (68Ga-) FAP-2286|PROCEDURE: Positron Emission Tomography (PET) imaging|DRUG: Copper-64 labeled (64Cu-) FAP-2286
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Preoperative Oral Heptaminol Hydrochloride in Preventing Hypotension After Spinal Anesthesia
Status: NOT_YET_RECRUITING
Conditions: Hypotension After Spinal Anesthesia
Interventions: DRUG: Heptaminol Hydrochloride|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Eculizumab for Prevention of Antibody-Mediated Rejection in ABO-Incompatible Living Donor Kidney Transplantation
Status: NOT_YET_RECRUITING
Conditions: Kidney Transplantation
Interventions: DRUG: Eculizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Gemcitabine_Capecitabine Versus Gemcitabine_Carboplatin in Breast Cancer
Status: UNKNOWN
Conditions: Metastatic Breast Cancer
Interventions: DRUG: Gemcitabine，Capecitabine|DRUG: Gemcitabine, Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study on Paclitaxel Plus Topotecan in Comparison With Topotecan Plus Cisplatin in Recurrent or Persistent Cervical Carcinoma
Status: UNKNOWN
Conditions: Recurrent, Persistent or Metastasized Cervical Cancer
Interventions: DRUG: Paclitaxel|DRUG: Cisplatin/Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Weaning Form Mechanical Ventilation Using Extracorporeal CO2 Removal
Status: UNKNOWN
Conditions: Patients With Acute Hypercapnic Respiratory Failure
Interventions: DEVICE: Extracorporeal CO2 removal device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Method Comparison Study for Measuring Potassium (K) and Ionized Calcium (iCa) in Blood
Status: NOT_YET_RECRUITING
Conditions: Potassium (K) and Ionized Calcium (iCa) in Capillary Whole Blood
Interventions: DIAGNOSTIC_TEST: Fingerstick blood draw
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Reducing Readmission for Frail Elderly Patients With Decompensated Heart Failure
Status: COMPLETED
Conditions: Heart Failure|Acute Decompensated Heart Failure|Fragility|Emergencies
Interventions: BEHAVIORAL: Intervention Group|OTHER: Control Group (Standard Care)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Supporting Family Caregivers of Palliative Patients at Home: the Carer Support Needs Assessment Intervention
Status: COMPLETED
Conditions: Family Caregiving for a Palliative Patient
Interventions: OTHER: Existing home care nursing practice|OTHER: Practice support tool intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of Modified Post-Anesthetic Discharge Scoring System (PADSS) Between 6 and 24 Hours in Patients Undergoing Total Knee Arthroplasty
Status: RECRUITING
Conditions: Total Knee Arthroplasty
Interventions: BEHAVIORAL: PADSS
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Relative Bioavailability and Food Effect for Darunavir/Cobicistat/Emtricitabine/Tenofovir Alafenamide Fixed Dose Combination
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Darunavir/Cobicistat/Emtricitabine/Tenofovir alafenamide FDC|DRUG: Elvitegravir /Cobicistat/Emtricitabine/Tenofovir alafenamide FDC|DRUG: Darunavir|DRUG: Emtricitabine/Tenofovir alafenamide (FTC/TAF)|DRUG: Cobicistat|OTHER: High-fat Breakfast|OTHER: Standardized Regular Breakfast
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Can a Self-guided Mobile Phone Application Program Improve Wellbeing in University Students
Status: UNKNOWN
Conditions: Perfectionism|Shame|Depression, Anxiety|Stress|Self-Compassion
Interventions: BEHAVIORAL: Cognitive Behavioural Therapy|BEHAVIORAL: Self-Compassion|BEHAVIORAL: Active Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study Comparing Citalopram Hydrobromide Tablets 40 mg (Torrent Pharmaceuticals Ltd) and RLD Tablets 40 mg (Manufactured By Forest Pharmaceuticals Inc, Missouri) in 24+2 Normal Healthy Male Subjects in Fed Condition
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Citalopram Hydrobromide
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose:
Clinical trial: Randomized Controlled Trial of Big Brothers Big Sisters Mentoring for Prevention of Crime and Delinquency
Status: ACTIVE_NOT_RECRUITING
Conditions: Crime|Juvenile Delinquency
Interventions: BEHAVIORAL: Big Brothers Big Sisters Community-Based Mentoring Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Ultrasound-guided Lavage of Calcific Deposits of the Rotator Cuff
Status: RECRUITING
Conditions: Rotator Cuff Tendinitis|Ultrasonography, Interventional|Ultrasonography, Doppler, Color
Interventions: PROCEDURE: Ultrasound-Guided Puncture and Lavage (UGPL)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Escitalopram in Asthma Patients With Frequent Exacerbation
Status: NOT_YET_RECRUITING
Conditions: Asthma
Interventions: DRUG: Escitalopram|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Chest Physiotherapy and Lungs Squeezing Technique in Patients With Chronic Obstructive Pulmonary Disease.
Status: RECRUITING
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: OTHER: Chest physical Therapy|OTHER: Lungs squeezing technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Anti-HIV Therapy on the Immune Systems of Children and Young Adults Infected With HIV
Status: COMPLETED
Conditions: HIV Infections
Interventions: BIOLOGICAL: Tetanus toxoid|BIOLOGICAL: Hepatitis A Vaccine (Inactivated)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: First-in-Human Study of TSHA-101 Gene Therapy for Treatment of Infantile Onset GM2 Gangliosidosis
Status: ACTIVE_NOT_RECRUITING
Conditions: Infantile GM2 Gangliosidosis (Disorder)
Interventions: BIOLOGICAL: TSHA-101
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Ultra-Processed Food Intake on Gingival Tissue Health
Status: RECRUITING
Conditions: Gingivitis|Ultra-processed Food|Prevention
Interventions: BEHAVIORAL: Full-mouth ultrasonic debridement plus Nutritional counseling|OTHER: Full-mouth ultrasonic debridement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Research Study Looking at How Well Semaglutide Works in People Suffering From Obesity and Knee Osteoarthritis
Status: COMPLETED
Conditions: Obesity
Interventions: DRUG: semaglutide 2.4 mg|DRUG: semaglutide 2.4 mg (placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dose De-escalation Study of the PI3k Alpha/Delta Inhibitor, Copanlisib Given in Combination With the Immunotherapeutic Agents, Nivolumab and Rituximab in Patients With Relapsed/Refractory Indolent Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Indolent Lymphoma
Interventions: DRUG: Copanlisib|DRUG: Nivolumab|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunointervention With Calcitriol in New-Onset Type 1 Diabetes
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: DRUG: 1,25-dihydroxy-vitamin D3 (calcitriol)|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: PREVENTION
Clinical trial: RELVAR Effects on Parasternal Muscle Activity, Diaphragm, and Ventilation in Severe COPD
Status: ACTIVE_NOT_RECRUITING
Conditions: Copd
Interventions: PROCEDURE: Ventilation|PROCEDURE: Parasternal EMG|PROCEDURE: Phrenic magnetic stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Trial of Nonpharmacologic Interventions in Elderly (TONE)
Status: COMPLETED
Conditions: Cardiovascular Diseases|Heart Diseases|Hypertension|Vascular Diseases
Interventions: BEHAVIORAL: diet, reducing|BEHAVIORAL: diet, sodium-restricted
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: |Primary Purpose: TREATMENT
Clinical trial: Multi-DOSE Oral Ondansetron for Pediatric Acute GastroEnteritis
Status: RECRUITING
Conditions: Acute Gastroenteritis|Viral Illness|Vomiting|Diarrhea
Interventions: DRUG: Ondansetron Oral Solution|DRUG: Oral Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cognitive Functions After TIVA With Dexmedetomidine
Status: COMPLETED
Conditions: Postoperative Confusion
Interventions: DRUG: Remifentanil|DRUG: Propofol|DRUG: Dexmedetomidine|DRUG: Rocuronium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Investigation Of Safety And Pharmacokinetics Following A Single Oral Dose Of 300 Mg Maraviroc In Healthy Male Japanese Volunteers
Status: COMPLETED
Conditions: Human Immunodeficiency Virus (HIV) Infection
Interventions: DRUG: maraviroc (Selzentry, Celsentri)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: De Novo Everolimus Versus Tacrolimus in Combination With Mofetil Mycophenolate and Low Dose Corticosteroids to Reduce Tacrolimus Induced Nephrotoxicity in Liver Transplantation: a Prospective, Multicentric, Randomised Study
Status: WITHDRAWN
Conditions: Liver Transplantation
Interventions: DRUG: Tacrolimus|DRUG: Everolimus|DRUG: Mycophenolate mofetil|DRUG: Prednisolone, Prednisone or Methylprednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Choice of Anesthesia for Endovascular Treatment of Acute Ischemic Stroke in Posterior Circulation
Status: COMPLETED
Conditions: Posterior Circulation Brain Infarction
Interventions: PROCEDURE: General anesthesia|PROCEDURE: Local anesthesia/concious sedation|PROCEDURE: Spontaneous breath|PROCEDURE: Controlled ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Safety and Efficacy Study in Patients With Local Advanced Larynx/Hypolarynx Carcinoma Treated With TPF Induction Chemotherapy Followed by Hyperfractionated Radiotherapy With Cetuximab
Status: TERMINATED
Conditions: Laryngeal Neoplasms
Interventions: OTHER: Docetaxel+Cisplatin+5-FU+ Radiotherapy+Cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Controlled Trial of the Impact of Mobile Phone Delivered Reminders and Travel Subsidies to Improve Childhood Immunization Coverage Rates and Timeliness in Western Kenya
Status: COMPLETED
Conditions: Diphtheria|Tetanus|Pertussis|Hepatitis B|Haemophilus Influenzae Type b|Measles
Interventions: OTHER: SMS reminder|OTHER: Travel subsidy|OTHER: Travel subsidy 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Safety Study of a Vaccine Against Meningitis in Infants ( 2,4 & 6 Months Age) After a Birth Dose of Hepatitis B.
Status: COMPLETED
Conditions: Diphtheria|Hepatitis B|Whole Cell Pertussis|Haemophilus Influenzae Type b|Tetanus
Interventions: BIOLOGICAL: Tritanrix-HepB/Meningitec conjugate vaccine|BIOLOGICAL: Tritanrix/Hiberix vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: |Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate FK778 in Kidney Transplant Patients
Status: COMPLETED
Conditions: Kidney Transplantation|Renal Transplantation|Transplantation, Renal|Transplantation, Kidney|Grafting, Kidney
Interventions: DRUG: FK778
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Steroids After Laser Trabeculoplasty for Glaucoma
Status: COMPLETED
Conditions: Glaucoma
Interventions: DRUG: Prednisolone 1%|DRUG: Ketorolac|DRUG: Artificial Tears
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Different Titration Schedules of ALKS 5461 in Adults With Major Depressive Disorder (MDD)
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: ALKS 5461
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Convalescent Plasma and Placebo for the Treatment of COVID-19 Severe Pneumonia
Status: COMPLETED
Conditions: SARS Virus|SARS-CoV-2|COVID-19
Interventions: OTHER: Convalescent SARS COVID-19 plasma|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial to Evaluate the Safety and Effectiveness of MatrixOssTM Bone Graft
Status: UNKNOWN
Conditions: Dental Diseases
Interventions: DEVICE: MatrixOssTM Bone Graft plus Bio-Gide membrane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Gut Microbiota and Behcet's Syndrome: a Dietary Intervention Trial (MAMBA Study)
Status: COMPLETED
Conditions: Behcet Syndrome
Interventions: BEHAVIORAL: Vegetarian diet|BEHAVIORAL: Mediterranean diet with butyrate|BEHAVIORAL: Mediterranean diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Ravulizumab in Pediatric Participants With HSCT-TMA
Status: ACTIVE_NOT_RECRUITING
Conditions: Thrombotic Microangiopathy
Interventions: DRUG: Ravulizumab|OTHER: Best Supportive Care
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Safety and Pharmacokinetics of XL147 (SAR245408) in Adults With Solid Tumors or Lymphoma
Status: COMPLETED
Conditions: Cancer|Lymphoma
Interventions: DRUG: XL147 (SAR245408)|DRUG: XL147 (SAR245408)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Erlotinib and Radiation Therapy Plus Combination Chemotherapy in Treating Patients With Inoperable Stage III Non-Small Cell Lung Cancer
Status: TERMINATED
Conditions: Adenocarcinoma of the Lung|Bronchoalveolar Cell Lung Cancer|Large Cell Lung Cancer|Squamous Cell Lung Cancer|Stage IIIA Non-small Cell Lung Cancer|Stage IIIB Non-small Cell Lung Cancer
Interventions: DRUG: cisplatin|DRUG: etoposide|DRUG: erlotinib hydrochloride|RADIATION: radiation therapy|DRUG: docetaxel|DRUG: paclitaxel|DRUG: carboplatin|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of First Oral Feeding by the Mother on Preterm Infants' Feeding Performance and Physiological Symptoms
Status: RECRUITING
Conditions: Premature|Breast Feeding|Bottle Feeding
Interventions: OTHER: oral feeding
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Forodesine in the Treatment of Cutaneous T-Cell Lymphoma
Status: COMPLETED
Conditions: Cutaneous T-cell Lymphoma (CTCL),
Interventions: DRUG: Forodesine 200 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Accuracy of New Tests for TB Infection Diagnosis
Status: NOT_YET_RECRUITING
Conditions: Latent Tuberculosis|TB Infection|Tuberculosis
Interventions: DIAGNOSTIC_TEST: Cy-TB test|DIAGNOSTIC_TEST: STANDARD F TB-Feron FIA test
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Leap Motion Based Gamefication Exercises in the Individuals With Systemic Sclerosis
Status: NOT_YET_RECRUITING
Conditions: Rheumatology|Scleroderma, Systemic|Video Games|Physiotherapy|Rehabilitation|Hand Rheumatism
Interventions: OTHER: Leap motion assisted rehabilitation|OTHER: Traditional program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: m-Health Supportive Care Transition Program in Improving Post-Discharged Outcomes
Status: COMPLETED
Conditions: Traumatic Brain Injury|Caregiver Burden|Stress
Interventions: OTHER: m-Health Transition Care Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Trial to Find Out How Safe REGN7075 is and How Well it Works in Combination With Cemiplimab for Adult Participants With Advanced Cancers
Status: RECRUITING
Conditions: Advanced Solid Tumors
Interventions: DRUG: REGN7075|DRUG: cemiplimab|DRUG: Platinum-based doublet chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Efficacy of the Melanocyte Keratinocyte Transplantation Procedure in the Treatment of Vitiligo
Status: TERMINATED
Conditions: Vitiligo
Interventions: PROCEDURE: MKTP with Surgical blade|DEVICE: MKTP with Negative Pressure Instrument|DEVICE: Suction blister grafting without cell dissociation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of a Music Therapist Designed Listening Program on Intraoperative Vitrectomy
Status: COMPLETED
Conditions: Pain, Postoperative|Music Therapy
Interventions: BEHAVIORAL: vitrectomy with music listening
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of MLN8237 in Combination With Irinotecan and Temozolomide
Status: COMPLETED
Conditions: Neuroblastoma
Interventions: DRUG: MLN8237|DRUG: Irinotecan|DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Entecavir Prophylaxis for Hepatitis B Reactivation for CD20 Positive B-cell Lymphoma Patients With Resolved Hepatitis B (Negative Hepatitis B Surface Antigen, Positive Hepatitis B Core Antibody)
Status: RECRUITING
Conditions: Resolved Hepatitis B|CD20 Positive B-cell Lymphoma
Interventions: DRUG: Entecavir
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ablation Plus Tislelizumab Versus Ablation Alone for Intrahepatic Recurrent Early Stage HCC
Status: RECRUITING
Conditions: Recurrent Hepatocellular Carcinoma
Interventions: DRUG: Tislelizumab|PROCEDURE: Ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PRP vs PRP+IVC for Severe nPDR
Status: UNKNOWN
Conditions: Severe Nonproliferative Diabetic Retinopathy|Diabetic Retinopathy|Diabete Mellitus
Interventions: DRUG: Conbercept|PROCEDURE: Panretinal coagulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Potential Food Effect And Repeated Dosing of AX-024.HCl In Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: AX-024.HCl|DRUG: AX-024.HCl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Caudal Bupivacaine vs Bupivacaine Plus Two Doses of Dexmedetomidine for Postoperative Analgesia in Children
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: DRUG: Bupivacaine|DRUG: dexmedetomidine 1μg.kg-1|DRUG: dexmedetomidine 2μg.kg-1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rituxan and Abraxane for the Treatment of Patients With Inoperable Stage III and IV Malignant Melanoma
Status: UNKNOWN
Conditions: Malignant Melanoma of Skin Stage III|Metastatic Melanoma
Interventions: DRUG: Rituxan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of TNFerade™ Biologic With Concomitant Radiotherapy, Fluorouracil, and Hydroxyurea (TNF-FHX) in Patients With Head and Neck Cancer
Status: COMPLETED
Conditions: Head and Neck Cancer|Head and Neck Neoplasms
Interventions: DRUG: TNFerade biologic
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ondansetron Administration to WELL Children With Gastroenteritis Associated Vomiting in EDs in Pakistan
Status: COMPLETED
Conditions: Dehydration|Gastroenteritis|Vomiting|Diarrhea
Interventions: DRUG: Ondansetron|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of ALT-L9 to Determine Safety, Efficacy and Pharmacokinetics in Neovascular AMD
Status: COMPLETED
Conditions: Neovascular Age-related Macular Degeneration
Interventions: BIOLOGICAL: Eylea|BIOLOGICAL: ALT-L9
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Therapeutic Use of Tadekinig Alfa in Adult-onset Still's Disease
Status: COMPLETED
Conditions: Still's Disease, Adult-Onset
Interventions: BIOLOGICAL: Tadekinig alfa (recombinant human IL-18 binding protein)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Target-controlled Infusion Versus Patient-controlled Sedation With Propofol in Endoscopic Retrograde Cholangiopancreatography (ERCP)
Status: COMPLETED
Conditions: Sedation
Interventions: DEVICE: Patient-controlled sedation|DEVICE: Target-controlled infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Albumin Dialysis to Treat Patients With Hepatic Encephalopathy Using The Molecular Adsorbent Recirculating System (MARS)
Status: COMPLETED
Conditions: Hepatic Encephalopathy|Liver Failure|Hepatitis, Chronic|Liver Cirrhosis
Interventions: DEVICE: MARS|DRUG: Standard Medical Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transcutaneous Vagus Nerve Stimulation As a Pain Modulator in Knee Osteoarthritis
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: DEVICE: Transcutaneous Vagus Nerve Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Serum Concentration of Endogenous Estrogens and Sirtuin-1 After Administration of Atorvastatin and Quercetin:
Status: RECRUITING
Conditions: Coronary Artery Disease|Menopause
Interventions: DIETARY_SUPPLEMENT: Quercetin|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Optimal Duration of DAPT Following Treatment With Endeavor (Zotarolimus-eluting Stent) in Real-world Japanese Patients
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DRUG: Clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Proof of Concept Study of ANXV (Annexin A5) in Patients With Retinal Vein Occlusion
Status: ACTIVE_NOT_RECRUITING
Conditions: Retinal Vein Occlusion
Interventions: BIOLOGICAL: ANXV
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Erector Spinae Plane (ESP) Block on Surgery-related Stress Response in Cardiac Surgery With ERAS
Status: COMPLETED
Conditions: Surgery Stress
Interventions: PROCEDURE: Erector spinae plane block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Extended Platelet Parameters as a Means to Differentiate Immune Thrombocytopenia From Hypo-proliferative Thrombocytopenias.
Status: COMPLETED
Conditions: Immune Thrombocytopenia|Chemotherapy Induced Thrombocytopenia|Myelodysplasia|Aplastic Anaemia
Interventions: OTHER: Immune Thrombocytopenics|OTHER: Hypo-proliferative thrombocytopenics|OTHER: Control Population
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Oral Immunotherapy (OIT) for Peanut Allergy
Status: COMPLETED
Conditions: Peanut Hypersensitivity
Interventions: DRUG: Peanut OIT|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Roasted Pulse Snacks, Post-prandial Food Intake, Appetite, and Glycemia
Status: COMPLETED
Conditions: Normal Weight|Overweight|Normoglycemic
Interventions: OTHER: Corn nuts|OTHER: Chickpeas|OTHER: Yellow peas|OTHER: Pinto beans|OTHER: Soybeans|OTHER: Almonds
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Feasibility of Ethanolization of Vein of Marshall With Specific Catheter in Atrial Fibrillation Ablation
Status: RECRUITING
Conditions: Atrial Fibrillation
Interventions: DEVICE: Marshall ethanolisation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effectiveness of Opiate Replacement Therapy Administered Prior to Release From a Correctional Facility - 1
Status: COMPLETED
Conditions: HIV Prevention|Opioid-Related Disorders
Interventions: BEHAVIORAL: Pre-release Initiation of MMT|BEHAVIORAL: Post Release Initiation of MMT.|BEHAVIORAL: Standard of Care Plus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of PEGASYS (Pegylated-interferon Alfa-2a) With or Without Ribavirin in Patients With Chronic Hepatitis C Who Have Participated in Previous Roche or Roche Partner Protocols
Status: COMPLETED
Conditions: Hepatitis C, Chronic
Interventions: DRUG: Pegylated-interferon alfa-2a|DRUG: Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SYD985 vs. Physician's Choice in Participants With HER2-positive Locally Advanced or Metastatic Breast Cancer
Status: COMPLETED
Conditions: Metastatic Breast Cancer
Interventions: DRUG: (vic-)trastuzumab duocarmazine|DRUG: Physician's choice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Perceived Experience of Patients Treated With Aligners With Two Different Timings
Status: NOT_YET_RECRUITING
Conditions: Malocclusion
Interventions: DEVICE: Biomax Nuvola aligners|DEVICE: Biomax Nuvola aligners
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Aminophylline on Recovery in Functional Endoscopic Sinus Surgery Under Dexmedetomidine Hypotensive Anesthesia
Status: COMPLETED
Conditions: Aminophylline|Dexmedetomidine|Functional Endoscopic Sinus Surgery
Interventions: DRUG: Aminophylline group|DRUG: normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ED90 of Remimazolam Loading Dose for Sedation in Patients Under Monitored Anesthetic Care
Status: COMPLETED
Conditions: Remimazolam|Orthopedic Procedures|Sedatives
Interventions: DRUG: Remimazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Increasing Physical Activity Through Personalised Motivational Messaging to Improve Cognitive Function in Lung Cancer Survivors
Status: NOT_YET_RECRUITING
Conditions: Neoplasms|Lung Cancer|Physical Inactivity|Cognitive Impairment
Interventions: BEHAVIORAL: Regular message delivery|BEHAVIORAL: Chat-type support message delivery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Myeloproliferative Neoplasms: an In-depth Case-control Study
Status: COMPLETED
Conditions: Polycythemia Vera|Essential Thrombocythemia|Primary Myelofibrosis
Interventions: OTHER: Methodological pens|OTHER: Methodological compensation|OTHER: Methodological trolley tokens
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Learn More About How Well the Study Treatment Finerenone Works, How Safe it is, How it Moves Into, Through, and Out of the Body, and the Effects it Has on the Body When Taken With an ACE Inhibitor or Angiotensin Receptor Blocker in Children With Chronic Kidney Disease and Proteinuria
Status: RECRUITING
Conditions: Chronic Kidney Disease|Proteinuria
Interventions: DRUG: Finerenone (Kerendia, BAY94-8862)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Epigenetic Regulation of Human Adipose Tissue Distribution
Status: ACTIVE_NOT_RECRUITING
Conditions: Obesity
Interventions: OTHER: Dual-energy X-ray absorptiometry (DEXA)/ Magnetic resonance imaging (MRI) and Magnetic resonance spectroscopy (MRS)|PROCEDURE: Adipose tissue biopsies|OTHER: FSIGTT/ RMR
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE