pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Phase III Study to Evaluated Morning Testosterone Normalization in Men With Secondary Hypogonadism
Status: COMPLETED
Conditions: Secondary Hypogonadism
Interventions: DRUG: Androxal|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Tolerability of Tested Formula After 3 Months in Treatment of Facial Hyperpigmentation of 3 Origins
Status: RECRUITING
Conditions: Hyperpigmentation
Interventions: OTHER: tested product (2039125 03)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Evaluation Of Cloumella Strut Effect In Tip Rotation
Status: COMPLETED
Conditions: Nose Deformities, Acquired
Interventions: PROCEDURE: rhinoplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Topotecan in Treating Patients With Advanced Ovarian Epithelial, Fallopian Tube, or Primary Peritoneal Cancer
Status: COMPLETED
Conditions: Fallopian Tube Cancer|Ovarian Cancer|Primary Peritoneal Cavity Cancer
Interventions: DRUG: topotecan hydrochloride|PROCEDURE: adjuvant therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Study of Pharmacodynamics, Pharmacokinetics, Safety and Tolerability of VAY736 in Patients With Idiopathic Pulmonary Fibrosis
Status: TERMINATED
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: DRUG: VAY736|DRUG: Placebo|DRUG: Standard of Care (SoC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Chemotherapy With Nab-paclitaxel in Women With HER2-negative High-risk Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Abraxane|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Monocentric Study of Taste in Patients With Minor or Major Cognitive Disorders Such as Alzheimer's, Through the Analysis of Gustatory Evoked Potentials.
Status: COMPLETED
Conditions: Cognitive Disorders
Interventions: BIOLOGICAL: Blood sampling|OTHER: Cognitive Assessment|OTHER: Subjective taste tests|OTHER: Objective taste tests
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: First-in-Human Study of FLX925 in Subjects With Relapsed or Refractory Acute Myeloid Leukemia
Status: TERMINATED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: FLX925
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Prognostic Modification in COVID-19 Patients in Early Intervention Treatment
Status: COMPLETED
Conditions: Covid19
Interventions: DRUG: Azithromycin / Ivermectin / Ribaroxaban / Paracetamol|DRUG: Azithromycin / Ribaroxaban / Paracetamol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Safety of Tooth Bleaching Procedure Using Y10 Whitening Toothpaste and RF Current
Status: WITHDRAWN
Conditions: Tooth Bleaching
Interventions: DEVICE: The Y10 Tooth Whitening system including the Y10 toothpaste and the Y10 device|OTHER: OTC toothpaste and an unoperated Y10 device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the CHK1 Inhibitor BBI-355, an ecDNA-directed Therapy (ecDTx), in Subjects With Tumors With Oncogene Amplifications
Status: RECRUITING
Conditions: Non-small Cell Lung Cancer|Non-Small Cell Lung Adenocarcinoma|Non-Small Cell Squamous Lung Cancer|Head and Neck Squamous Cell Carcinoma|Esophageal Cancer|Gastric Cancer|Breast Cancer|Bladder Cancer|Ovarian Cancer|Endometrial Cancer|Liposarcoma
Interventions: DRUG: BBI-355|DRUG: Erlotinib|DRUG: Futibatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase Ib/II Trial of Interleukin-2 and PD-1 Checkpoint Inhibitor, Nivolumab In Metastatic Clear Cell Renal Cell Cancer
Status: COMPLETED
Conditions: Renal Cell Carcinoma
Interventions: DRUG: Interleukin-2|DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of CT-P27 in an Influenza Challenge Model
Status: COMPLETED
Conditions: Influenza A
Interventions: DRUG: CT-P27|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Framework For Linking Sequential Pattern Rules in DLD: Perception in Toddlers
Status: RECRUITING
Conditions: Developmental Language Disorder|Speech Sound Disorder|Specific Language Impairment
Interventions: OTHER: Sensitivity to phonological rules & referents OR: Toddlers|OTHER: Sensitivity to phonological rules & referents FR: Toddlers
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Transcutaneous Electrical Acupoint Stimulation on Obstetric Quality of Recovery-10 After Cesarean Section
Status: COMPLETED
Conditions: Recovery
Interventions: DEVICE: Transcutaneous Electrical Acupoint Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Dose Response to the Norepinephrine Precursor Droxidopa in Hypotensive Individuals With Spinal Cord Injury
Status: COMPLETED
Conditions: Hypotension, Orthostatic|Hypotension|Spinal Cord Injuries
Interventions: DRUG: Northera|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of a Specific Enteral Diet for Diabetics
Status: UNKNOWN
Conditions: Hyperglycemia|Diabetics|Metabolic Syndrome
Interventions: DIETARY_SUPPLEMENT: T-Diet plus Standard|DIETARY_SUPPLEMENT: T-Diet plus Diabet NP|DIETARY_SUPPLEMENT: Glucerna|DIETARY_SUPPLEMENT: Novasource
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Topical Steroids & Bacterial Decolonization for Radiation Dermatitis
Status: WITHDRAWN
Conditions: Radiation Dermatitis
Interventions: DRUG: Bacterial decolonization|DRUG: Mometasone furoate 0.1% cream|DRUG: Bacterial decolonization and Mometasone furoate 0.1% cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Impact of PIVC Length and Gauge on Catheter Indwell Time
Status: COMPLETED
Conditions: Indication for Peripheral Intravenous Catheterisation
Interventions: DEVICE: Peripheral Intravenous Catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Clinical Effects in Cervical Spinal Mobilization and Oscillation Mobilization in Neck Pain
Status: COMPLETED
Conditions: Manual Therapy|Neck Pain
Interventions: OTHER: Spine Mobilizations|OTHER: Vertebral Resonant Oscillation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Open, Prospective, Multicenter Study of Trimetrexate With Leucovorin Rescue for AIDS Patients With Pneumocystis Carinii Pneumonia (PCP) and Serious Intolerance to Approved Therapies
Status: COMPLETED
Conditions: Pneumonia, Pneumocystis Carinii|HIV Infections
Interventions: DRUG: Trimetrexate glucuronate|DRUG: Leucovorin calcium
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GM-CSF and Rituximab After Autologous Stem Cell Transplant in Treating Patients With Relapsed or Refractory Follicular Non-Hodgkin Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: BIOLOGICAL: filgrastim|BIOLOGICAL: rituximab|BIOLOGICAL: sargramostim|DRUG: carmustine|DRUG: cytarabine|DRUG: etoposide|DRUG: melphalan|PROCEDURE: autologous hematopoietic stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Human Albumin Versus Hydroxyethylstarch in Renal Transplant Recipients
Status: COMPLETED
Conditions: Anesthesia Morbidity
Interventions: OTHER: Albumin resuscitation|OTHER: Hydroxyethylstarch resuscitation|DRUG: Albumin 5%|DRUG: Hydroxyethylstarch 6%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: PTFE Stents for Treatment of Malignant Biliary Strictures
Status: UNKNOWN
Conditions: Bile Duct Stricture|Bile Duct Cancer|Pancreas Cancer
Interventions: DEVICE: Stenting with PTFE-coated stent (HILZO)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nivolumab and Pomalidomide in Treating Patients With Relapsed or Refractory Central Nervous System Diffuse Large B Cell Lymphoma or Primary Vitreoretinal Diffuse Large B Cell Lymphoma
Status: COMPLETED
Conditions: Recurrent Nervous System Lymphoma|Recurrent Primary Vitreoretinal DLBCL|Refractory Nervous System Lymphoma|Refractory Primary Vitreoretinal DLBCL
Interventions: BIOLOGICAL: Nivolumab|DRUG: Pomalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination of Cryosurgey and NK Immunotherapy for Recurrent Laryngeal Cancer
Status: COMPLETED
Conditions: Recurrent Laryngeal Cancer
Interventions: DEVICE: Cryosurgery|BIOLOGICAL: NK immunotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Structured Treatment Interruptions With or Without Pegylated Interferon Alpha for HIV-Infected Patients After Prolonged Viral Suppression
Status: TERMINATED
Conditions: HIV Infections
Interventions: DRUG: Interferon alfa-2b|PROCEDURE: Structured treatment interruptions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Standard Opioid Prescription Versus Prescription Guided by Pharmacogenetic Analysis in Patients With Non-cancerous Chronic Pain.
Status: WITHDRAWN
Conditions: Non-cancerous Chronic Pain
Interventions: OTHER: Pharmacogenetic analysis allowing personalized opioid prescription|OTHER: Standard opioid prescription
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: FEIBA and Use of Blood Products in Cardiac Surgery
Status: COMPLETED
Conditions: Cardiovascular Disease
Interventions: DRUG: FEIBA|DRUG: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Exercise and Music on Sleep, Quality of Life and Emotional State in Children With Epilepsy
Status: RECRUITING
Conditions: Epilepsy in Children
Interventions: OTHER: Progressive relaxation exercise group|OTHER: Music recital group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: CAsein GLycomacropeptide in Ulcerative Colitis - Anti-Inflammatory and Microbiome Modulating Effects (CAGLUCIM)
Status: COMPLETED
Conditions: Colitis, Ulcerative|Inflammatory Bowel Diseases
Interventions: DIETARY_SUPPLEMENT: Casein glycomacropeptide (CGMP)|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Validation of the French Version of the Inflammatory Bowel Disease Questionnaire (IBDQ) for Ulcerative Colitis and Crohn's Disease
Status: COMPLETED
Conditions: Ulcerative Colitis|Crohn's Disease
Interventions: OTHER: Validation of the French Version of the Inflammatory Bowel Disease Questionnaire (IBDQ)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety of Evinacumab in Adult Patients With Severe Hypertriglyceridemia for the Prevention of Recurrent Acute Pancreatitis
Status: TERMINATED
Conditions: Hypertriglyceridemia
Interventions: DRUG: evinacumab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Efficacy, Tolerability and Pharmacokinetics of AGN-223575 Ophthalmic Suspension in Patients With Dry Eye Disease
Status: COMPLETED
Conditions: Dry Eye Syndromes
Interventions: DRUG: AGN-223575 ophthalmic solution|DRUG: AGN-223575 vehicle ophthalmic solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An Efficacy And Safety Study Of Tanezumab For The Treatment Of Pain Associated With Chronic Abacterial Prostatitis
Status: COMPLETED
Conditions: Chronic Prostatitis With Chronic Pelvic Pain Syndrome
Interventions: DRUG: Tanezumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Discontinuation of Antidepressant Medication in Primary Care.
Status: COMPLETED
Conditions: Antidepressants
Interventions: BEHAVIORAL: Supported Protocolized Discontinuation (SPD)|BEHAVIORAL: Mindfulness Based Cognitive Therapy (MBCT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Effectiveness of Ondansetron Versus Dexamethasone Versus Placebo for the Control of Intraoperative Nausea and Vomiting in Patients Undergoing Lower-segment Caesarean Section Under Spinal Anesthesia
Status: NOT_YET_RECRUITING
Conditions: Caesarean Section|Spinal Anesthesia
Interventions: DRUG: Ondansetron 8mg|DRUG: Dexamethasone 8mg|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of an Intervention Based on Back School in an Aquatic Environment on Non-specific Low Back Pain
Status: NOT_YET_RECRUITING
Conditions: Low Back Pain|Exercise|Healthy
Interventions: BEHAVIORAL: Aquatic program based on the back school
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing Intravenous and Oral Paracetamol for Cholecystectomy
Status: COMPLETED
Conditions: Laparoscopic Cholecystectomy
Interventions: DRUG: Paracetamol (acetaminophen)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: The Effects of a Wrist Extensors Exercise With Blood Flow Restriction (BFR) in Lateral Elbow Tendinopathy.
Status: ENROLLING_BY_INVITATION
Conditions: Lateral Epicondylitis
Interventions: OTHER: Exercise with Blood Flow Restriction (BFR)|OTHER: Exercise without Blood Flow Restriction (BFR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Sinusitis Hevert SL Tablets Compared to Placebo in Adult Patients With Acute, Uncomplicated Rhinosinusitis
Status: COMPLETED
Conditions: Acute Rhinosinusitis
Interventions: DRUG: Sinusitis Hevert SL Tablet|DRUG: Placebo for Sinusitis Hevert SL Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Contralateral Acupuncture in the Treatment of Chronic Shoulder Pain
Status: COMPLETED
Conditions: Shoulder Pain
Interventions: PROCEDURE: Acupuncture|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: EnDovascular Therapy Plus Best Medical Treatment (BMT) Versus BMT Alone for MedIum VeSsel Occlusion sTroke
Status: RECRUITING
Conditions: Acute Ischemic Stroke
Interventions: PROCEDURE: Endovascular Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase III Study to Evaluate the Efficacy, Immunogenicity and Safety of the 9-valent HPV Vaccine in Chinese Males
Status: RECRUITING
Conditions: Genital Wart|Penile Cancer|Anal Cancer|PIN-1|PIN2|PIN3|AIN1|AIN2|AIN3|HPV-Related Carcinoma
Interventions: BIOLOGICAL: 9-valent Human Papillomavirus (Types 6, 11, 16, 18, 31, 33, 45, 52 and 58) Recombinant Vaccine (Hansenula Polymorpha)|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: PD-1 Inhibitor Tislelizumab Maintenance Therapy in R/R DLBCL Patients After ASCT
Status: UNKNOWN
Conditions: Lymphoma, Large B-Cell, Diffuse|Transplantation|Chemotherapy
Interventions: DRUG: PD-1 Inhibitor Tislelizumab maintenance therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Acupuncture and Laser Acupuncture in the Treatment of People With Chronic Nonspecific Low Back Pain.
Status: UNKNOWN
Conditions: Low Back Pain
Interventions: OTHER: Acupuncture|OTHER: Laser acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Maudsley Model of Anorexia Nervosa Treatment for Adolescents and Young Adults (MANTR-a)
Status: UNKNOWN
Conditions: Anorexia Nervosa|Anorexia
Interventions: BEHAVIORAL: MANTR-a treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prostate Cancer Active Surveillance Trigger Trial (PCASTT-UK): Comparing Current Practice for Men With Prostate Cancer on Active Surveillance (AS) to an AS Protocol With Standardised Triggers for Transitioning to Curative Treatment
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Cancer
Interventions: PROCEDURE: Active Surveillance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Drug Drug Interaction (DDI) Study of Pirtobrutinib (LOXO-305) and Digoxin (P-Glycoprotein Substrate) in Healthy Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Pirtobrutinib|DRUG: Digoxin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pharmacotoxicology of Trichloroethylene Metabolites
Status: TERMINATED
Conditions: Healthy
Interventions: DRUG: Dichloroacetate|GENETIC: Genotyping|OTHER: Leucine|OTHER: tyrosine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect of Listening to Surah Al-Inshirah on Pain and Anxiety After Laparoscopic Cholecystectomy Surgery
Status: COMPLETED
Conditions: Patients of Laparoscopic Cholecystectomy
Interventions: BEHAVIORAL: Surah Inshirah
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Study to YD312 Tablet in Patients With Diabetic Macular Edema
Status: UNKNOWN
Conditions: Diabetic Macular Edema(DME)
Interventions: DRUG: YD312 50mg|DRUG: YD312 150mg|DRUG: YD312 350mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Safety and Tolerability of KH001 in Dentin Hypersensitivity Patients
Status: COMPLETED
Conditions: Dentin Sensitivity
Interventions: DRUG: KH001|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Problem-Solving Intervention for Women With Suicidal Ideation During Postnatal Period in Pakistan
Status: RECRUITING
Conditions: Postnatal Depression
Interventions: BEHAVIORAL: Culturally Adapted Manual Assisted Therapy (CMAP-SI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: MPDL3280A and Stereotactic Ablative Radiotherapy in Patients With Non-small Cell Lung Cancer
Status: TERMINATED
Conditions: Recurrent Non-Small Cell Lung Carcinoma|Stage IV Non-Small Cell Lung Cancer
Interventions: DRUG: Anti-PD-L1 Monoclonal Antibody MPDL3280A|RADIATION: Stereotactic Body Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 99mTc-rhAnnexin V-128 Imaging and Cardiotoxicity in Patients With Early Breast Cancer
Status: TERMINATED
Conditions: Breast Cancer|Doxorubicin Induced Cardiomyopathy
Interventions: RADIATION: 99mTc-rhAnnexin V-128
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Caracterization of the Combined Alterations in Respiration and aROUSal in Patients With Drug-resistant EpiLepsy
Status: NOT_YET_RECRUITING
Conditions: Epilepsy
Interventions: PROCEDURE: Video-EEG monitoring|PROCEDURE: Respiratory monitoring and polysomnography|PROCEDURE: 1 Hypercapnic challenge while participant is awake|PROCEDURE: 2 Hypercapnic challenges while participant is sleeping|PROCEDURE: Auditory stimulus|OTHER: Questionnaires
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A New Way of Cardiac Denervation to Reduce the Incidence of AF After CABG.
Status: COMPLETED
Conditions: Cardiac Denervation|Postoperative Atrial Fibrillation
Interventions: PROCEDURE: cardiac denervation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Investigator Initiated Phase 1 Study of TBI-1201
Status: COMPLETED
Conditions: Solid Tumors
Interventions: DRUG: TBI-1201|DRUG: Cyclophosphamide|DRUG: Fludarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Ganglion Sphenopalatine Block (GSP-block) Versus Placebo on Postdural Puncture Headache
Status: COMPLETED
Conditions: Postdural Puncture Headache|Sphenopalatine Ganglion Block
Interventions: PROCEDURE: Ganglion sphenopalatine block with local anesthetic|PROCEDURE: Ganglion sphenopalatine block with placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Does Vascular Endothelial Growth Factor (VEGF) or Complement Factor H Gene Polymorphism Play a Role in the Treatment Success With VEGF Inhibitors in Patients With Choroidal NeoVascularization (CNV)?
Status: WITHDRAWN
Conditions: Choroidal NeoVascularization|Age-Related Macular Degeneration
Interventions: GENETIC: VEGF genotyping
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: ABI-007 in Taxol Resistant Patients With Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Neoplasms|Metastases, Neoplasm
Interventions: DRUG: ABI-007
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Seroepidemiological Study of SARS-CoV-2 (COVID-19) Infection in Population Subgroups in the State of São Paulo
Status: COMPLETED
Conditions: COVID|SARS-CoV 2
Interventions: DIAGNOSTIC_TEST: Serological test|DIAGNOSTIC_TEST: Nasopharyngeal Swab|DIAGNOSTIC_TEST: Oropharyngeal Swab
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Acoustic Radiation Force Impulse-Imaging in Comparison to Transient Elastography for Liver Fibrosis Staging in HCV
Status: COMPLETED
Conditions: Chronic Hepatitis C
Interventions: DEVICE: FibroScan|DEVICE: Acoustic Radiation Force Impulse (ARFI)- Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: DIAGNOSTIC
Clinical trial: Randomized Trial of EUS-guided Gastrojejunostomy and Surgical Gastrojejunostomy in Gastric Outlet Obstruction
Status: RECRUITING
Conditions: Gastric Outlet Obstruction
Interventions: PROCEDURE: EUS-guided gastrojejunostomy|PROCEDURE: Surgical gastrojejunostomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Comfort Level Following an Intravitreal Injection by 30 or 32 Gauge Needles
Status: UNKNOWN
Conditions: Pain
Interventions: DEVICE: Eye injection by 30 or 32 gauge needle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: AAV9 U7snRNA Gene Therapy to Treat Boys With DMD Exon 2 Duplications.
Status: ACTIVE_NOT_RECRUITING
Conditions: Duchenne Muscular Dystrophy
Interventions: BIOLOGICAL: scAAV9.U7.ACCA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ruxolitinib as GVHD Prophylaxis in AA Patients
Status: NOT_YET_RECRUITING
Conditions: The Prophylactic Value of Ruxolitinib for aGVHD in HSCT Recipients of AA
Interventions: DRUG: Ruxolitinib 5 MG BID Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of AZD2014 and Palbociclib in Patients With Estrogen Receptor Positive (ER+) Metastatic Breast Cancer
Status: COMPLETED
Conditions: Advanced and Metastatic Breast Cancer
Interventions: DRUG: AZD2014|DRUG: Palbociclib|DRUG: Fulvestrant
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single and Multiple Ascending Dose Pharmacokinetic Study of TR701 in Healthy Adults
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: TR-701|DRUG: linezolid|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Immunonutrition in Total Hip Arthroplasty
Status: COMPLETED
Conditions: Arthroplasty, Hip Replacement|Perioperative Care|Nutritional Support
Interventions: DIETARY_SUPPLEMENT: Impact
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Hemodynamic and Cardiac Effects of Individualized PEEP Titration Using Esophageal Pressure Measurements in ARDS Patients
Status: WITHDRAWN
Conditions: Severe Acute Respiratory Distress Syndrome / Severe ARDS|Invasive Mechanical Ventilation|Individualized PEEP Treatment Strategy
Interventions: PROCEDURE: individualized PEEP treatment, Invasive mechanical ventilation, ECMO,
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: BMT-08: A Comparative Effectiveness Study of Transdermal Granisetron to Ondansetron
Status: RECRUITING
Conditions: Chemotherapy-induced Nausea and Vomiting
Interventions: DRUG: Granisetron Transdermal Patch|DRUG: Intravenous Dexamethasone|DRUG: Ondansetron
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effectiveness of the Massage and the Hypopressive Abdominal Gymnastics on Low Back Pain (MAS-GAH)
Status: COMPLETED
Conditions: Low-back Pain
Interventions: PROCEDURE: GROUP RECEIVING MASSOTHERAPY- HYPOPRESSIVE ABDOMINAL GYMNASTIC|PROCEDURE: GROUP RECEIVING MASSOTHERAPY|PROCEDURE: GROUP RECEIVING HYPOPRESSIVE ABDOMINAL GYMNASTIC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Optimizing Anesthesia for Post Partum Tubal Ligations
Status: TERMINATED
Conditions: Pregnancy Related
Interventions: DRUG: Chloroprocaine|DRUG: Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Review of Surgical Management of Congenital Pulmonary Airway Malformations (CPAM): A Decade of Experience
Status: COMPLETED
Conditions: Pulmonary Arteriovenous Malformation|Congenital Disorders
Interventions: PROCEDURE: Thoracoscopic CPAM resection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Germline Alterations of Tumor Susceptibility Genes in New York Cancer Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer|Bladder Cancer|Kidney Cancer|Colon Cancer|Prostate Cancer|Lung Cancer|Ovarian Cancer
Interventions: GENETIC: PCR/PCR/LDR Strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Assessment of the Impact of Type of Probiotic, Delivery Type and Feeding Type on Baby's Microbiota After Dysbiotic Delivery
Status: RECRUITING
Conditions: Dysbiosis
Interventions: DIETARY_SUPPLEMENT: L. reuteri|DIETARY_SUPPLEMENT: B. longum and P. Pentosaceus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Dry Needling for Patients With Neck Pain
Status: COMPLETED
Conditions: Neck Pain
Interventions: OTHER: Dry Needling|OTHER: Sham Dry Needling|OTHER: Manual Therapy|OTHER: Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigating the Effectiveness of PelvicSense(R) on Pain and Sexual Outcomes in Provoked Vestibulodynia
Status: RECRUITING
Conditions: Provoked Vestibulodynia
Interventions: BEHAVIORAL: PelvicSense(R)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: FIRE AND ICE: Comparative Study of Two Ablation Procedures in Patients With Atrial Fibrillation
Status: COMPLETED
Conditions: Symptomatic Paroxysmal Atrial Fibrillation (PAF)
Interventions: PROCEDURE: Electrical isolation of the pulmonary veins|PROCEDURE: Electrical isolation of pulmonary veins
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of Different Analgesic Options in Kidney Stone Pain Management
Status: COMPLETED
Conditions: Renal Colic|Urinary Calculi
Interventions: DRUG: Diclofenac|DRUG: Morphine|DRUG: Paracetamol|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective Comparison of 18F-choline PET/CT and 18F-FDG PET/CT in the Initial Work-up of Multiple Myeloma
Status: UNKNOWN
Conditions: Myeloma Multiple
Interventions: DRUG: Positron Emission Tomography using 18F-FCH|DRUG: Positron Emission Tomography using 18F-FDG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Risk Adapted De-Intensification of Radio-Chemotherapy for Oropharyngeal Squamous Cell Carcinoma
Status: RECRUITING
Conditions: Oropharyngeal Squamous Cell Carcinoma
Interventions: RADIATION: Radiation therapy|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Metastatic Soft Tissue Sarcoma (STS) Patients (FIBROSARC USA)
Status: RECRUITING
Conditions: Leiomyosarcoma
Interventions: DRUG: Doxorubicin|COMBINATION_PRODUCT: L19TNF plus doxorubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of LY3209590 in Healthy Participants and Participants With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: LY3209590|DRUG: Placebo|DRUG: Insulin Glargine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Six-Week Safety Study of an Investigational Ophthalmic Solution
Status: COMPLETED
Conditions: Allergic Conjunctivitis
Interventions: DRUG: AL-4943A Ophthalmic Solution|DRUG: AL-4943A Ophthalmic Solution Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Effects of Treatment Changes on Fat Wasting in the Arms and Legs of HIV Patients
Status: COMPLETED
Conditions: HIV Infections|Lipodystrophy|Wasting Disease
Interventions: DRUG: Abacavir sulfate|DRUG: Atazanavir/Ritonavir|DRUG: Lopinavir/Ritonavir|DRUG: Nevirapine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study Comparing Single Long BioMimeTM Morph Coronary Stent System vs. Two Overlapping Xience Family Coronary Stent Systems in the Treatment of Patients With Long de Novo Lesions.
Status: UNKNOWN
Conditions: Coronary Artery Disease
Interventions: DEVICE: BioMime™ Morph - Sirolimus Eluting Coronary Stent System|DEVICE: Xience family Everolimus Coronary Stent Systems
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PIPAC in Multimodal Therapy for Patients With Oligometastatic Peritoneal Gastric Cancer
Status: RECRUITING
Conditions: Oligometastatic Gastric Adenocarcinoma
Interventions: COMBINATION_PRODUCT: FOLFOX and PIPAC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Local Wound Infiltration With 0.5% Levobupivacaine for Postoperative Pain After Laparoscopic Colorectal Surgery.
Status: COMPLETED
Conditions: Laparoscopic Colorectal Surgery|Colorectal Cancer
Interventions: PROCEDURE: 0.5% Levobupivacaine|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: INC424 for Patients With Primary Myelofibrosis, Post Polycythemia Myelofibrosis or Post-essential Thrombocythemia Myelofibrosis.
Status: COMPLETED
Conditions: Myelofibrosis
Interventions: DRUG: INC424
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Diazoxide Choline in Patients With Prader-Willi Syndrome
Status: COMPLETED
Conditions: Prader-Willi Syndrome
Interventions: DRUG: DCCR|DRUG: Placebo for DCCR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Placebo Controlled Trial of Depakote ER in Alcohol Dependent Patients With Mood and/or Anxiety Symptoms
Status: COMPLETED
Conditions: Alcoholism|Alcohol Related Disorders|Mood Disorders
Interventions: DRUG: divalproex sodium extended release
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Ozonized In-office and Domiciliary Gels vs Chlorhexidine Gel 1% for the Management of Peri-implant Mucositis Sites
Status: COMPLETED
Conditions: Peri-implant Mucositis
Interventions: OTHER: Ozoral Pro and Ozoral gel administration|OTHER: Curasept chlorhexidine gel 1%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mobile Ostomates Resources for Patients and Caregivers
Status: ACTIVE_NOT_RECRUITING
Conditions: Bladder Cancer|Colorectal Cancer
Interventions: OTHER: STOMA Care web-based application|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: An Evaluation of an SCCD on the Symptomatology of Painful DPN
Status: UNKNOWN
Conditions: Painful Diabetic Neuropathy
Interventions: DEVICE: Flowaid FA-100 SCCD
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pipeline™ Vantage Embolization Device With Shield Technology™ for Wide-Necked Intracranial Aneurysms (ADVANCE)
Status: TERMINATED
Conditions: Intracranial Aneurysm
Interventions: DEVICE: Pipeline™ Vantage Embolization Device with Shield Technology™
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radiofrequency Versus Laser Ablation for Hepatocellular Carcinoma
Status: COMPLETED
Conditions: Carcinoma, Hepatocellular|Neoplasms, Liver
Interventions: PROCEDURE: percutaneous radiofrequency ablation|PROCEDURE: percutaneous laser ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preventative Skin Care for Children Undergoing Targeted CNS Tumor Therapy
Status: ACTIVE_NOT_RECRUITING
Conditions: Pediatric Cancer|CNS Tumor, Childhood|Skin Inflammation
Interventions: OTHER: Warm Baths or Showers|OTHER: Moisturizer|DRUG: SPF 30 or Higher Suncreen|OTHER: Sun Protective Clothing|BEHAVIORAL: Limited Sun Exposure|OTHER: Dilute bleach baths
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Open-label, Multi-center Protocol to Provide QTI571 to PAH Patients Who Participated in the Extension Study (A2301E1) in Japan
Status: COMPLETED
Conditions: Severe Pulmonary Arterial Hypertension
Interventions: DRUG: QTI571
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Conbercept Ophthalmic Injection for Patients of Central Retinal Vein Occlusion
Status: COMPLETED
Conditions: Macular Edema|Central Retinal Vein Occlusion
Interventions: DRUG: Conbercept Ophthalmic Injection|DRUG: sham injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Demineralized Dentin Graft With Hydrochloric Acid Versus Nitric Acid in Alveolar Ridge Preservation
Status: UNKNOWN
Conditions: Alveolar Bone Loss
Interventions: PROCEDURE: Alveolar ridge preservation after extraction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trastuzumab and Erlotinib as First-Line Therapy in Treating Women With Metastatic Breast Cancer Associated With HER2/Neu Overexpression
Status: COMPLETED
Conditions: Breast Cancer
Interventions: BIOLOGICAL: trastuzumab|DRUG: erlotinib hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Postoperative Morphine Consumption After Caesarean Section- TAP Block vs Intracutaneous Infiltration
Status: COMPLETED
Conditions: Pregnancy
Interventions: PROCEDURE: TAP block|PROCEDURE: control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Exploratory Study to Investigate Cognition Function and Mobility in Individuals With Pain
Status: TERMINATED
Conditions: Pain
Interventions: DRUG: Paracetamol and caffeine|DRUG: Paracetamol|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Study of Two Dose Levels of RTA 402 in Patients With Advanced Malignant Melanoma
Status: WITHDRAWN
Conditions: Malignant Melanoma
Interventions: DRUG: RTA 402 Dose1|DRUG: RTA 402 Dose2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acute Effects of Open and Closed Suction Systems in Mechanically Ventilated Patients
Status: COMPLETED
Conditions: Mechanical Ventilation
Interventions: PROCEDURE: Closed suction system|PROCEDURE: Open suction system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Reducing Preoperative Anxiety in Parents of Surgical Patients
Status: COMPLETED
Conditions: Anxiety
Interventions: PROCEDURE: Story book with information about surgery techniques|PROCEDURE: Video with information about surgery techniques|PROCEDURE: Story book and Video with information about surgery techniques
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Foley's Catheter Balloon Plus Tranexamic Acid During Cesarean Delivery for Placenta Previa
Status: UNKNOWN
Conditions: Placenta Previa
Interventions: PROCEDURE: Foley's Catheter|DRUG: TA|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Ability of Songha Night ® to Improve Sleep in Patients With Mild to Moderate Sleep Disturbances
Status: COMPLETED
Conditions: Sleep Initiation and Maintenance Disorders
Interventions: DRUG: Songha Night ®|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Effects of Nicotine Replacement and Repeated Cue Exposure on Cigarette Craving
Status: COMPLETED
Conditions: Tobacco Use Disorder
Interventions: BEHAVIORAL: Cue Extinction Training|DRUG: Nicotine Replacement Therapy|BEHAVIORAL: Cue Extinction Therapy|BEHAVIORAL: Progressive Muscle Relaxation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Metastasis-directed Therapy for Oligometastases of Breast Cancer
Status: RECRUITING
Conditions: Breast Cancer|Oligometastasis|Metastatic Breast Cancer
Interventions: DRUG: Systemic therapy for 12 weeks after primary registration|PROCEDURE: Radiation therapy (SBRT/conventional RT)|PROCEDURE: Surgery|DRUG: Same systemic therapy after secondary registration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study on the Effect of Exercise Intervention Combined With Physical Therapy on Chronic Ankle Instability Symptoms
Status: COMPLETED
Conditions: Chronic Ankle Instability,CA
Interventions: BEHAVIORAL: Exercise Intervention|BEHAVIORAL: Instrument-Assisted Soft Tissue Mobilization|BEHAVIORAL: Tuinal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anti-inflammatory and Antioxidant Effects of Resveratrol on Healthy Adults.
Status: COMPLETED
Conditions: Chronic Subclinic Inflammation|Redox Status
Interventions: DIETARY_SUPPLEMENT: Resveratrol|DIETARY_SUPPLEMENT: resveratrol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Plerixafor as a Salvage Regimen to Mobilize Allogeneic Stem Cells in Healthy Volunteers
Status: COMPLETED
Conditions: Blood Stem Cell Harvest Failure
Interventions: DRUG: Plerixafor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Alemtuzumab in Treatment Refractory MS Subjects/Alemtuzumab Naive & Alemtuzumab Experienced Subjects
Status: UNKNOWN
Conditions: Multiple Sclerosis
Interventions: DRUG: Alemtuzumab|DRUG: Alemtuzumab immunotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT