pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Malaysian COVID-19 Anosmia Study (Phase 2) - A Nationwide Multicentre Case-Control Study
Status: UNKNOWN
Conditions: SARS-CoV Infection|COVID-19|Anosmia|Dysgeusia
Interventions: OTHER: Patient-Reported Online Questionnaire on Olfactory & Taste Disturbances
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Zenker's Diverticulum Treatment Using Peroral Endoscopic Myotomy and Flexible Endoscopy Septotomy.
Status: UNKNOWN
Conditions: Zenker Diverticulum|Diverticulum, Esophago-Pharyngeal|Diverticulum, Esophageal|Dysphagia|Gastrointestinal Disease
Interventions: PROCEDURE: Peroral endoscopic myotomy|PROCEDURE: Flexible endoscopic septotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Absolute Bioavailability and Pharmacokinetics of Simeprevir (TMC435) Administered as Single Oral Doses of TMC435 and an Intravenous Microdose of [3H]-TMC435 in Healthy Male Patients
Status: COMPLETED
Conditions: Healthy Male Participants
Interventions: DRUG: Simeprevir (TMC435)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gonorrhoea Resistance Assessment by Nucleic Acid Detection (GRANDII)
Status: ACTIVE_NOT_RECRUITING
Conditions: Drug Resistance, Microbial|Antimicrobial Stewardship|Gonorrhea
Interventions: OTHER: Resistance guided treatment for gonorrhoea infection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mobile and Scalable Innovations for Measles Immunization: a Randomized Controlled Trial
Status: COMPLETED
Conditions: Measles
Interventions: BEHAVIORAL: SMS reminder|BEHAVIORAL: Unconditional Incentive
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Dose Finding Study of [177Lu]Lu-NeoB in Newly Diagnosed Glioblastoma and in Recurrent Glioblastoma
Status: RECRUITING
Conditions: Newly Diagnosed and Recurrent Glioblastoma
Interventions: DRUG: [177Lu]Lu-NeoB|DRUG: [68Ga]Ga-NeoB|OTHER: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of the Unified Protocol for the Transdiagnostic Treatment (UP-A; Ehrenreich-May et al., 2018) for Adolescents With Moderate Emotional Symptoms in Educational Settings
Status: UNKNOWN
Conditions: Anxiety Disorder|Depressive Disorder|Emotional Problem|Emotional Disorder
Interventions: BEHAVIORAL: UPA|BEHAVIORAL: Active control condition (Progressive Relaxation Training)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Study to Determine and Compare Plasma and Intrapulmonary Pharmacokinetics of WCK 2349 in Healthy Adult Human Subjects
Status: COMPLETED
Conditions: Intrapulmonary Pharmacokinetics of WCK 2349
Interventions: DRUG: WCK-2349
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparative Effectiveness of Metformin for Type 2 Diabetes With Chronic Kidney Disease
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Renal Insufficiency, Chronic
Interventions: DRUG: Metformin|DRUG: Sulfonylurea|DRUG: DPP-4 inhibitor|DRUG: SGLT2 inhibitor|DRUG: GLP1 receptor agonist
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Probiotic (VSL #3) for Gulf War Illness
Status: TERMINATED
Conditions: Gulf War Illness
Interventions: DRUG: VSL#3|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Epidural Opioid Administered in the First A Period on the Progress of Labour
Status: UNKNOWN
Conditions: Anesthesia, Epidural|Opioid|Labor Pain
Interventions: DRUG: Fentanyl|DRUG: Sufentanil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Does a Rescue Course of Betamethasone in Pregnant Women With PPROM Decrease Neonatal Morbidity?
Status: TERMINATED
Conditions: PPROM|Respiratory Distress Syndrome in Premature Infants
Interventions: DRUG: Betamethasone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SHARON: A Clinical Trial for Metastatic Cancer With a BRCA or PALB2 Mutation Using Chemotherapy and Patients' Own Stem Cells
Status: RECRUITING
Conditions: Pancreatic Adenocarcinoma Metastatic|BRCA1 Mutation|BRCA2 Mutation|Pancreatic Acinar Cell Carcinoma|Pancreatic Ductal Adenocarcinoma|Pancreatic Cancer|Metastatic Pancreatic Cancer|Metastatic Pancreatic Ductal Adenocarcinoma|Breast Cancer Metastatic|Breast Cancer Stage IV|Pancreatic Cancer Stage IV|HER2-negative Breast Cancer|HER2 Negative Breast Carcinoma|Adenocarcinoma of the Breast|PALB2 Gene Mutation
Interventions: DRUG: Melphalan|DRUG: BCNU|DRUG: Vitamin B12B|DRUG: Vitamin C|DRUG: Ethanol|DEVICE: Autologous Hematopoietic Stem Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Azento IIS 3 Year Outcomes Implant Study
Status: ENROLLING_BY_INVITATION
Conditions: Tooth Loss
Interventions: DEVICE: Atlantis Abutment|PROCEDURE: Intra-oral photographs|DEVICE: provisional crown (te + 12 weeks)|OTHER: medical history|OTHER: dental history|PROCEDURE: suture removal|PROCEDURE: intra-oral digital scan|DIAGNOSTIC_TEST: wound healing index|OTHER: pain|OTHER: level of satisfaction|PROCEDURE: debridement|OTHER: oral hygiene|OTHER: Shade selection|OTHER: photographs|PROCEDURE: plaque removal|OTHER: probing depth|OTHER: Bleeding on probing|OTHER: recession|OTHER: keratinized mucosa height|OTHER: plaque index|OTHER: gingival index|DEVICE: provisional crown (te + 24 weeks)|DEVICE: provisional crown (te + 36 weeks)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Venetoclax and Azacitidine for the Treatment of Relapsed or Refractory High-Risk Myelodysplastic Syndrome or Chronic Myelomonocytic Leukemia
Status: RECRUITING
Conditions: Recurrent Chronic Myelomonocytic Leukemia|Recurrent Myelodysplastic Syndrome|Refractory Chronic Myelomonocytic Leukemia|Refractory Myelodysplastic Syndrome|Therapy-Related Myelodysplastic Syndrome
Interventions: DRUG: Azacitidine|DRUG: Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of GSK5764227 in Participants With Advanced Solid Tumors
Status: NOT_YET_RECRUITING
Conditions: Neoplasms
Interventions: DRUG: GSK5764227|DRUG: Topotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Benign Prostatic Hyperplasia and Ischemic Heart DIsease
Status: COMPLETED
Conditions: Ischaemic Heart Disease (IHD)|Benign Prostatic Hyperplasia (BPH)|Lower Urinary Tract Symptoms (LUTS)
Interventions: DRUG: Tamsulosin Oral Capsule|PROCEDURE: TURP
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RESPeCT: Revlimid Early Stage Poor Prognosis Chronic Lymphocytic Leukaemia (CLL) Trial
Status: TERMINATED
Conditions: Chronic Lymphocytic Leukaemia
Interventions: DRUG: Lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of DEXamethasone in Patients With Acute Hypoxemic REspiratory Failure Caused by INfEctions
Status: RECRUITING
Conditions: Acute Hypoxemic Respiratory Failure
Interventions: DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: STOP HCC: Mailed HCV Treatment Outreach Program for HCC Prevention
Status: COMPLETED
Conditions: Hepatitis C|HepatoCellular Carcinoma
Interventions: BEHAVIORAL: Mailed outreach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Reperfusion of Pulmonary Arteriovenous Malformations After Embolotherapy
Status: COMPLETED
Conditions: Pulmonary Arteriovenous Malformations
Interventions: PROCEDURE: Angiography and embolotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: De-escalated Radiation for Human Papillomavirus-Positive Squamous Cell Carcinoma of the Oropharynx
Status: RECRUITING
Conditions: HPV Positive Oropharyngeal Squamous Cell Carcinoma
Interventions: RADIATION: Intensity-Modulated Radiation Therapy (IMRT)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Predictive Factors for Complete Myoma Resection During Hysteroscopic Myomectomy
Status: UNKNOWN
Conditions: Uterine Fibroids|Uterine Myomas
Interventions: DIAGNOSTIC_TEST: Transvaginal ultrasound|BEHAVIORAL: Anamnesis|PROCEDURE: Operative hysteroscopy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Diagnosis of Obstetric Anal Sphincter Injuries (OASIs) Using Transperineal Ultrasound Scan (TPUS)
Status: COMPLETED
Conditions: Obstetric Anal Sphincter Injury
Interventions: DIAGNOSTIC_TEST: three dimensional Transperineal Ultrasound Scan
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Cardiovascular Health and Text Messaging-Diabetes Mellitus (CHAT-DM) Study
Status: COMPLETED
Conditions: Coronary Artery Disease|Diabetes
Interventions: BEHAVIORAL: Text messaging
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: 5% Lidocaine Ointment in the Treatment of Vulvar Vestibulitis
Status: TERMINATED
Conditions: Vulvar Vestibulitis
Interventions: DRUG: 5% topical lidocaine ointment|DRUG: Placebo cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility of a Non-invasive, Trans-abdominal, Low Cost Fetal Oximetry Probe on Pregnant Human Subjects
Status: TERMINATED
Conditions: Pregnancy, Abdominal
Interventions: DEVICE: Raydiant Oximetry Sensor System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Post-Marketing Use Of CT-P13 (Infliximab) For Standard Of Care Treatment Of Rheumatoid Diseases Who Are Naïve To Biologics Or Switched From Remicade
Status: COMPLETED
Conditions: Rheumatoid Diseases|Rheumatoid Arthritis|Ankylosing Spondylitis|Psoriatic Arthritis
Interventions: DRUG: CT-P13
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: PEG-rhG-CSF in Lymphoma Patients After Autologous Hematopoietic Stem Cell Transplantation
Status: UNKNOWN
Conditions: Lymphoma
Interventions: DRUG: PEG-rhG-CSF|DRUG: rhG-CSF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Product Performance of the PureVision®2 High Definition (HD) Contact Lens
Status: COMPLETED
Conditions: Myopia
Interventions: DEVICE: PureVision2 HD contact lenses|DEVICE: Spectacles
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: - 4th Visit at 17 Years of Cohort STANISLAS - Stanislas Ancillary Study ESCIF
Status: COMPLETED
Conditions: Cardiovascular Diseases
Interventions: BIOLOGICAL: blood and urine samples|GENETIC: blood sample|OTHER: cardiovascular assessment|OTHER: Stanislas ancillary study : MRI examination with GRICS technique
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Relation Between Cachexia, Diabetes and periNeural Invasion in PANcreatic Cancer- Biomarkers Substudy
Status: COMPLETED
Conditions: Pancreatic Cancer, Adult|Cachexia|Pain|Diabetes Mellitus
Interventions: DIAGNOSTIC_TEST: Point-of care biomarkers|OTHER: Clinical, venous blood samples, pancreatic tissue|OTHER: Follow-up
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Biotene OralBalance Gel for Oral Care in Critically-Ill Mechanically Ventilated Neonates
Status: COMPLETED
Conditions: Ventilator-associated Pneumonia
Interventions: DRUG: Biotene OralBalance® gel|OTHER: Sterile Water moisten cotton tipped applicator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Impact of Disease Activity and Nutrition Treat on Postoperative Recurrence and Complications After Bowel Resection for Crohn's Disease
Status: COMPLETED
Conditions: Crohn's Disease
Interventions: DIETARY_SUPPLEMENT: nutrition treat|OTHER: surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Dienogest for Treatment of Adenomyotic Uteri
Status: COMPLETED
Conditions: Adenomyosis
Interventions: DRUG: Dienogest group|DRUG: Gestodene-Ethinyl Estradiol|RADIATION: Ultrasound|OTHER: visual analogue scale
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Probiotic in Infant Growth, Allergy and Immunity Study
Status: NOT_YET_RECRUITING
Conditions: Healthy|Infant ALL
Interventions: DIETARY_SUPPLEMENT: Probiotic BLa80|OTHER: Placebo Maltodextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Transcranial Direct Current Stimulation (tDCS) in Young Individuals With Major Depressive Disorder: a Literature Review and Feasibility Study
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DEVICE: Sooma tDCS portable device - active stimulation|DEVICE: Sooma tDCS portable device - sham stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fecal Microbiota Transplantation (FMT) in the Management of Active Ulcerative Colitis
Status: COMPLETED
Conditions: Ulcerative Colitis
Interventions: BIOLOGICAL: Fecal Microbiota Transplant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low-Dose Leptin and the Formerly-Obese
Status: UNKNOWN
Conditions: Obesity
Interventions: DRUG: Leptin|BEHAVIORAL: Dietary modification|DRUG: T3 repletion
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Phase II Study of the Safety and Efficacy of the Relay Thoracic Stent-Graft
Status: COMPLETED
Conditions: Thoracic Aortic Aneurysms|and Penetrating Atherosclerotic Ulcers
Interventions: DEVICE: Relay Thoracic Stent-Graft|PROCEDURE: Open Repair
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Effect of Atorvastatin for Reducing Aging-related Complication in HIV-infected Patients Older Than 45 Years Receiving a Protease Inhibitor-based Regimen Versus a Raltegravir-based Regimen
Status: COMPLETED
Conditions: Aging-related Inflammation in HIV-infected Patients
Interventions: DRUG: Raltegravir|DRUG: PI-based regimen|DRUG: Atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessing The Effectiveness of a Preoperative High Intensity Interval Training Programme In Older Colorectal Cancer Patients
Status: COMPLETED
Conditions: Preoperative Care|Colorectal Neoplasms|Aged|Exercise
Interventions: BEHAVIORAL: HIT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Single-Dose Pharmacokinetics Study of Tapimycin Injection
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Tapimycin (piperacillin 4 g + tazobactam 0.5g)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Up-front CART-BCMA With or Without huCART19 in High-risk Multiple Myeloma
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Myeloma
Interventions: COMBINATION_PRODUCT: BCMA CART + huCART19|COMBINATION_PRODUCT: CART BCMA or CART BCMA + huCART19|COMBINATION_PRODUCT: Single-dose infusion of CART BCMA or CART BCMA + huCART19|COMBINATION_PRODUCT: BCMA CART + huCART19
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Intermittent Hepatic Inflow Occlusion During Donor Hepatectomy In Living Donor Liver Transplantation
Status: UNKNOWN
Conditions: End Stage Liver Disease|Living Donor
Interventions: PROCEDURE: Intermittent hepatic inflow occlusion (IHIO)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TEP Versus Open Repair of Sportsman's Hernia
Status: UNKNOWN
Conditions: Chronic Pain|Bone Marrow Oedema
Interventions: PROCEDURE: open repair|PROCEDURE: endoscopic TEP repair
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Fenofibrate for Primary Biliary Cirrhosis
Status: COMPLETED
Conditions: Primary Biliary Cirrhosis
Interventions: DRUG: Fenofibrate IDD-P (Insoluble Drug Delivery-Micro Particle)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: WB-EMS and Individualized Nutritional Support in Gynecological Cancer Patients
Status: UNKNOWN
Conditions: Gynecologic Cancer|Cachexia
Interventions: OTHER: Whole-Body Electromyostimulation (WB-EMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Analgesic Effect of Music Listening During Pain Elicitation in Fibromyalgia
Status: TERMINATED
Conditions: Fibromyalgia
Interventions: BEHAVIORAL: Music Listening
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Safety Study of Fosaprepitant (MK-0517) Plus Ondansetron Versus Ondansetron Alone for the Prevention of Chemotherapy-Induced Nausea and Vomiting in Pediatric Participants (MK-0517-044)
Status: TERMINATED
Conditions: Chemotherapy-induced Nausea and Vomiting
Interventions: DRUG: Fosaprepitant|DRUG: Placebo for fosaprepitant|DRUG: Ondansetron|DRUG: Dexamethasone|DRUG: 5-HT3 antagonist
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Combined Single / Multiple Dose Escalation Study in Patients With Renal Anemia Due to CKD (Chronic Kidney Disease)
Status: COMPLETED
Conditions: Anemia
Interventions: DRUG: BAY85-3934|DRUG: BAY85-3934|DRUG: BAY85-3934|DRUG: BAY85-3934|DRUG: BAY85-3934|DRUG: BAY85-3934
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: GSK2190915 Moderate to Severe Asthma Study
Status: TERMINATED
Conditions: Asthma
Interventions: DRUG: GSK2190195 100mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Smartphone Application (ACT on Vaping) for Vaping Cessation in Young Adults
Status: COMPLETED
Conditions: Nicotine Dependence|Nicotine Addiction|Nicotine Use Disorder|Nicotine Vaping|Vaping
Interventions: BEHAVIORAL: Smartphone app|OTHER: Text Message|OTHER: Survey Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy Evaluation of UCB-MNCs in the Treatment of Refractory Neonatal Diseases
Status: RECRUITING
Conditions: Hypoxic-Ischemic Encephalopathy|Bronchopulmonary Dysplasia|Short Bowel Syndrome
Interventions: BIOLOGICAL: Mononuclear cells|DEVICE: Mild hypothermia therapy|DEVICE: Breathing support technique|PROCEDURE: Total parenteral nutrition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Curcumin for Pediatric Nonalcoholic Fatty Liver Disease
Status: WITHDRAWN
Conditions: NAFLD - Nonalcoholic Fatty Liver Disease|NASH - Nonalcoholic Steatohepatitis
Interventions: DRUG: phosphatidylcholine-curcumin complex supplement|DRUG: Placebo curcumin capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Post-Traumatic Knee Osteoarthritis Following Anterior Cruciate Ligament Reconstruction
Status: RECRUITING
Conditions: Anterior Cruciate Ligament Injuries|Post-Traumatic Osteoarthritis of Knee
Interventions: OTHER: Imaging - magnetic resonance imaging (MRI)|OTHER: Blood sampling|OTHER: Assessment of functionality and strength|OTHER: Activity monitoring|OTHER: Imaging - x-ray scan (RX)|BEHAVIORAL: Questionnaires
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study to Determine if Different Prosthetic Sockets Effect How Much Oxygen is in the Tissue of Lower Limb Amputees While They Are Walking
Status: COMPLETED
Conditions: Amputation|Diabetes Complications|Leg Injuries|Traumatic Amputation
Interventions: DEVICE: Pe-Lite and sleeve suspension socket|DEVICE: Total Surface bearing a socket with a sleeve suspension but without suction|DEVICE: Total surface bearing suction socket with a pin lock suspension|DEVICE: Total surface bearing suction socket with a sleeve suspension|DEVICE: Vacuum-assisted socket system (Harmony System, Otto Bock)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Virtual Reality Hypnosis Versus Inhaled Nitrous Oxide in Anterior Shoulder Dislocation Reduction: an Open Multicenter Randomized Controlled Trial
Status: RECRUITING
Conditions: Shoulder Dislocation
Interventions: PROCEDURE: Virtual reality hypnosis|DRUG: Nitrous oxide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Tezepelumab in Allergic Rhinitis and Asthma Study (TEZARS)
Status: RECRUITING
Conditions: Asthma With Allergic Rhinitis
Interventions: BIOLOGICAL: Tezepelumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Egg Cholesterol Consumption, Blood Cholesterol and Skeletal Muscle Hypertrophy
Status: UNKNOWN
Conditions: Sarcopenia|Cardiovascular Disease
Interventions: BEHAVIORAL: Resistance Training|BEHAVIORAL: Sedentary
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Early Lumbar Drainage Combined With Intrathecal Urokinase Injection for Treatment of Severe Aneurysmal SAH (LD-ITUK)
Status: RECRUITING
Conditions: Aneurysmal Subarachnoid Hemorrhage
Interventions: DRUG: Urokinase|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Repeat Dose Study of Fluticasone Propionate/Salmeterol Versus Fluticasone Propionate + Salmeterol In Asthmatics
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: fluticasone propionate/salmeterol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare Analyte Levels in Blood Collected Using an Investigational Collection Device With a Commercial Predicate
Status: WITHDRAWN
Conditions: Diabetes|Anemia
Interventions: DEVICE: TAP20-C|DEVICE: SAFE-T-FILL
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Relative Bioavailability of Single Dose Empagliflozin (BI 10773) When Co-administered With Multiple Doses of 600 mg Gemfibrozil Compared to Single Dose Treatment With Empagliflozin (BI 10773) When Given Alone in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BI 10773|DRUG: Gemfibrozil|DRUG: BI 10773
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate Lung Deposition of Inhaled Amikacin-loaded Liposomes in Healthy Male Participants
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Liposomal Amikacin for Inhalation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Perioperative Hemodynamic and Microcirculatory Physiological Study During TAVI
Status: COMPLETED
Conditions: Aortic Valve Stenosis
Interventions: DIAGNOSTIC_TEST: Determination of arterial compliance using blood pressure waveform analysis|DIAGNOSTIC_TEST: Measurement of plasma Vascular Endothelium Growth Factor|DIAGNOSTIC_TEST: Skin temperature gradient|DIAGNOSTIC_TEST: Vaso-occlusion test|DIAGNOSTIC_TEST: Transthoracic echocardiography|DIAGNOSTIC_TEST: Photoplethysmography|PROCEDURE: Transcatheter aortic valve insertion (TAVI)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical Performance of Two Frequent Replacement Silicone Hydrogel Multifocal Contact Lenses
Status: RECRUITING
Conditions: Presbyopia
Interventions: DEVICE: Serafilcon A multifocal contact lenses|DEVICE: Senofilcon A multifocal contact lenses|DEVICE: CLEAR CARE® Cleaning & Disinfecting Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Simple-Prep Controlled Embolic
Status: NOT_YET_RECRUITING
Conditions: Embolism|Vascular Tumor|Renal Angiomyolipoma|Renal Cell Carcinoma|Bone Tumor|Portal Vein Embolism
Interventions: DEVICE: GPX® Embolic Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of LY3848575 Versus Placebo in Participants With Painful Distal Sensory Polyneuropathy
Status: NOT_YET_RECRUITING
Conditions: Neuropathic Pain|Distal Sensory Polyneuropathy
Interventions: DRUG: LY3848575|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Utility of Intravitreal Methotrexate in Diabetic Macular Edema Resistant to Conventional Therapies
Status: TERMINATED
Conditions: Diabetic Macular Edema
Interventions: DRUG: Methotrexate intravenous 25mg/ml
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Renal Microvessel Imaging for Chronic Kidney Disease
Status: ENROLLING_BY_INVITATION
Conditions: Healthy|Chronic Kidney Diseases
Interventions: DRUG: Definity|DIAGNOSTIC_TEST: Super-resolution ultrasound imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation of Functional Outcomes at 2 Months According to Therapeutic Management, in Trauma With Low-grade Osteo-ligamentous Ankle Injury in Children
Status: TERMINATED
Conditions: Ankle Injuries|Ligament Injury
Interventions: DEVICE: below-knee soft resin cast|DEVICE: Below-knee rigid resin cast
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Preoperative Biliary Drainage Before Pancreatoduodenectomy
Status: UNKNOWN
Conditions: Pancreatic Cancer|Periampullary Carcinoma
Interventions: PROCEDURE: Pancreatoduodenectomy|PROCEDURE: ENBD and Pancreatoduodenectomy|PROCEDURE: EBD and Pancreatoduodenectomy|PROCEDURE: PTCD and Pancreatoduodenectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Anal Dilatation Plus Probiotics Before Ileostomy Reduction for Low Anterior Resection Syndrome
Status: UNKNOWN
Conditions: Low Anterior Resection Syndrome
Interventions: OTHER: Anal dilatation per anus|DRUG: administration of probiotics (Clostridium butyricum TO-A; Bacillus mesentericus TO-A; Streptococcus faecalisT-110) per anus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Muscle and Bone in Patients With Diabetes Mellitus and Neuropathy
Status: RECRUITING
Conditions: Diabetes Mellitus, Type 2|Diabetic Peripheral Neuropathy|Sarcopenia
Interventions: DIAGNOSTIC_TEST: Blood sampling|DIAGNOSTIC_TEST: Electromyoneurography (EMNG)|PROCEDURE: Muscle biopsy|RADIATION: Quantitative peripheral computed tomography (qPCT)|DEVICE: Mechanography|DIAGNOSTIC_TEST: Electrocardiography (ECG)|OTHER: Questionnaires|OTHER: Anthropometry
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Efficacy Study of Bimatoprost, Latanoprost, and Travoprost in Patients With Elevated Intraocular Pressure (IOP) and Open-angle Glaucoma (OAG)
Status: COMPLETED
Conditions: Open-Angle Glaucoma|Ocular Hypertension
Interventions: DRUG: bimatoprost 0.03%, latanoprost 0.005%, and travoprost 0.004%
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Patient-Reported Erectile Recovery and Quality of Life Outcomes With Lyopreserved Placental Tissue Applied Directly Over Neurovascular Bundle During Nerve Sparing Radical Prostatectomy Versus Standard of Care
Status: RECRUITING
Conditions: Prostate Cancer
Interventions: DRUG: Stravix lyopreserved placental tissue (LPT)|PROCEDURE: Radical prostatectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of JTT-705 in Combination With Atorvastatin 20 mg in Patients With Low High-Density Lipoprotein (HDL) Levels
Status: COMPLETED
Conditions: Dyslipidemia
Interventions: DRUG: JTT-705 600 mg and atorvastatin 20 mg|DRUG: Placebo and atorvastatin 20 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Drug-Drug Interaction Study Between Brigatinib and the CYP3A Substrate, Midazolam, in Participants With ALK-Positive or ROS1-Positive Solid Tumors
Status: COMPLETED
Conditions: Carcinoma, Advanced ALK+ or ROS1+Non-Small-Cell Lung, Neoplasm, Advanced ALK+ or ROS1+Solid Tumors
Interventions: DRUG: Midazolam|DRUG: Brigatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Palbociclib in Molecularly Characterized ER-positive/HER2-negative Metastatic Breast Cancer
Status: COMPLETED
Conditions: Metastatic Breast Cancer
Interventions: DRUG: Palbociclib|DRUG: Fulvestrant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Assessing Single and Multiple Doses of IDX21459 in Healthy and HCV-Infected Subjects
Status: TERMINATED
Conditions: Chronic Hepatitis C
Interventions: DRUG: IDX21459|DRUG: Matching Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Daily Caloric Restriction and Intermittent Fasting in Overweight and Obese Adults With Autosomal Dominant Polycystic Kidney Disease
Status: COMPLETED
Conditions: Polycystic Kidney, Autosomal Dominant
Interventions: BEHAVIORAL: Weight Loss
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Moderately Carbohydrate-restricted Diet to Treat NAFLD in Adolescents
Status: RECRUITING
Conditions: Non-Alcoholic Fatty Liver Disease|Obesity
Interventions: OTHER: Moderately carbohydrate-restricted diet|OTHER: Fat-restricted diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Marqibo in Metastatic Malignant Uveal Melanoma
Status: COMPLETED
Conditions: Metastatic Malignant Uveal Melanoma
Interventions: DRUG: Marqibo® (vincristine sulfate liposomes injection)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmaco-immunological Study of Interferon-alpha and Metronomic Cyclophosphamide Association in Neuroendocrine Tumors
Status: COMPLETED
Conditions: Neuroendocrine Tumors
Interventions: DRUG: Metronomic cyclophosphamide|DRUG: Interferon-alpha
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Neoadjuvant LDRT Combined With Durvalumab in Potentially Resectable Stage III NSCLC
Status: UNKNOWN
Conditions: Stage III Non-small Cell Lung Cancer
Interventions: DRUG: Durvalumab|DRUG: nanoparticle albumin bound paclitaxel|RADIATION: low dose radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Does the Mesh Have to be Fixed in Laparoscopic eTEP Repair of Inguinal Hernia?
Status: COMPLETED
Conditions: Migration of Implant|Pain|Postoperative Complications|Relapse
Interventions: PROCEDURE: TEP Group|PROCEDURE: eTEP Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Opportunities and Limits to Deprescribing in Nursing Homes:Quality Circle Deprescribing Module
Status: COMPLETED
Conditions: Polypharmacy|Inappropriate Prescribing
Interventions: OTHER: Quality Circle Deprescribing Module
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Modulation of Steroid Immunosuppression by Alveolar Efferocytosis
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive|Pneumonia, Bacterial
Interventions: PROCEDURE: Bronchoscopy with bilateral bronchoalveolar lavages
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Healthy Volunteer Study to Evaluate Reversibility of Induced Impairment of Cognition
Status: COMPLETED
Conditions: Cognition
Interventions: DRUG: AZD1446|DRUG: AZD1446|DRUG: donepezil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Functional Connectivity Alterations in Suicidal Patients Among Opioid Users
Status: RECRUITING
Conditions: Substance Abuse|Suicide|Depression
Interventions: DEVICE: Repetitive Transcranial Magnetic Stimulation (rTMS)|DEVICE: sham rTMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of High-flow Nasal Cannula Oxygen Therapy in Sepsis Patients
Status: UNKNOWN
Conditions: High Flow Nasal Cannula|Sepsis Syndrome
Interventions: DEVICE: A high flow oxygen device.|DEVICE: Conventional oxygen therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Bevacizumab in Combination With Verteporfin Reduced and Standard Fluence in the Treatment of Hemorrhaged Lesions in Neovascular AMD
Status: TERMINATED
Conditions: Macular Degeneration
Interventions: DEVICE: Verteporfin Therapy/ Drug: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Trial of SHR3680 With or Without SHR3162 in Prostate Cancer
Status: COMPLETED
Conditions: Neoplasm|Prostate Cancer
Interventions: DRUG: SHR3680; SHR3162
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Individualized Treatment in Treating Patients With Stage II-IVB Nasopharyngeal Cancer Based on EBV DNA
Status: ACTIVE_NOT_RECRUITING
Conditions: Epstein-Barr Virus Infection|Stage II Nasopharyngeal Carcinoma|Stage III Nasopharyngeal Carcinoma|Stage IVA Nasopharyngeal Carcinoma|Stage IVB Nasopharyngeal Carcinoma
Interventions: DRUG: Cisplatin|OTHER: Clinical Observation|DRUG: Fluorouracil|DRUG: Gemcitabine Hydrochloride|RADIATION: Intensity-Modulated Radiation Therapy|OTHER: Laboratory Biomarker Analysis|DRUG: Paclitaxel|OTHER: Quality-of-Life Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: VAccination in Early and ADvanced Prostate caNCEr
Status: UNKNOWN
Conditions: Intermediate Risk Prostate Cancer|Castration-resistant Prostate Cancer
Interventions: BIOLOGICAL: ChAdOx1-MVA 5T4 vaccine|DRUG: Nivolumab Infusion [Opdivo]
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Comparing Weekly Versus Every 3 Week Chemotherapy in Patients With Ovarian Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Ovarian Cancer
Interventions: PROCEDURE: carboplatin|DRUG: paclitaxel|DRUG: carboplatin|DRUG: paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Effectiveness of the Cryo-Touch II Device for the Treatment of Forehead and/or Glabellar Lines
Status: COMPLETED
Conditions: Facial Wrinkles|Skin Aging
Interventions: DEVICE: Cryo-Touch II
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Sedation Study of the MyoSure Hysteroscopic Tissue Removal System
Status: COMPLETED
Conditions: Uterine Fibroids|Polyps
Interventions: DEVICE: Hysteroscopic Morcellator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mechanisms for the Effect of Acetylcysteine on Renal Function After Exposure to Radiographic Contrast Material
Status: COMPLETED
Conditions: Radiocontrast-induced Nephropathy
Interventions: DRUG: Acetylcysteine|DRUG: Visipaque 320|DRUG: Visipaque 320
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Evaluation of a Nasal Pillows Mask for the Treatment of Obstructive Sleep Apnea (OSA)
Status: COMPLETED
Conditions: Sleep Disordered Breathing|Obstructive Sleep Apnea
Interventions: DEVICE: F&P Deimos Nasal Pillows Mask
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasound Impact in Rheumatoid Arthritis Patient Reported Outcomes
Status: COMPLETED
Conditions: Rheumatoid Arthritis|Patient Reported Outcomes|Musculoskeletal Ultrasound
Interventions: DIAGNOSTIC_TEST: MusculoSkeletal Ultrasound|DIAGNOSTIC_TEST: MusculoSkeletal Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: The SLeeping and Intake Methods Taught to Infants and Mothers Early in Life (SLIMTIME) Project
Status: COMPLETED
Conditions: Weight Gain|Obesity
Interventions: BEHAVIORAL: Infant Sleeping and Soothing|BEHAVIORAL: Repeated Food Exposure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Cost- Effectiveness Study of Brief Interventions for Mood and Anxiety Disorders
Status: COMPLETED
Conditions: Depressive Disorder|Anxiety Disorder
Interventions: OTHER: Cognitive behavioral treatment/farmacotherapy intervention|OTHER: Treatment As Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Second-Line Adjuvant Therapy With Nab-Paclitaxel Plus Gemcitabine Versus Oxaliplatin Plus Folinic Acid and Fluorouracil for Gemcitabine-Refractory Pancreatic Cancer After Curative Resection
Status: UNKNOWN
Conditions: Stage ⅠA Pancreatic Cancer|Stage ⅠB Pancreatic Cancer|Stage ⅡA Pancreatic Cancer|Stage ⅡB Pancreatic Cancer
Interventions: DRUG: nab-paclitaxel|DRUG: gemcitabine|DRUG: oxaliplatin|DRUG: folinic acid|DRUG: fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Phase III of PRRT Versus Interferon
Status: WITHDRAWN
Conditions: Gastro-intestinal Neuroendocrine Tumors
Interventions: DRUG: Interferon alpha-2b|DRUG: 177Lu-DOTATATE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Performance Study of the Electroencephalographic Recording Device and Sound Emissions
Status: WITHDRAWN
Conditions: Sleep Disorder
Interventions: DEVICE: Memowave emitting sounds|DEVICE: Memowave not emitting sounds
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Early Treatment of Acute Graft Versus Host Disease With Bone Marrow-Derived Mesenchymal Stem Cells and Corticosteroids
Status: TERMINATED
Conditions: Graft-Versus-Host Disease
Interventions: BIOLOGICAL: MSC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Microbiology, Safety and Tolerability of C16G2 Dental Strip Application
Status: COMPLETED
Conditions: Dental Caries
Interventions: DRUG: C16G2 Strip|OTHER: Placebo Strip
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Influence of Aerobic Exercise and HIIT on Glycemic Control in Adult Men With Type 1 Diabetes (TAILOR/1b)
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: PROCEDURE: Aerobic|PROCEDURE: High-intensity interval training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study to Assess Efficacy of Supporting Properties and Safety of ARTNEO in Patients With Knee Osteoarthritis
Status: COMPLETED
Conditions: Osteoarthritis|Osteo Arthritis Knee|Osteoarthritis, Knee
Interventions: DIETARY_SUPPLEMENT: ARTNEO|DRUG: Artra
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study to Treat Patients Who Have Signs and Symptoms of Benign Prostatic Hyperplasia (BPH) With Tadalafil Daily
Status: COMPLETED
Conditions: Benign Prostatic Hyperplasia
Interventions: DRUG: Placebo|DRUG: tadalafil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Double Blind, Placebo-Controlled, Randomised Investigation of Ondansetron in Schizophrenia
Status: COMPLETED
Conditions: Schizoaffective and Schizophreniform Disorders|Schizophrenia
Interventions: DRUG: Ondansetron|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intracervical Anesthesia and Pain Associated With Intrauterine Contraceptive Insertion
Status: COMPLETED
Conditions: Pain, Acute|Anesthesia, Local|IUD Insertion Complication
Interventions: DRUG: Anesthesia|PROCEDURE: Dry-needling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Gene Therapy for Wiskott-Aldrich Syndrome (WAS)
Status: COMPLETED
Conditions: Wiskott-Aldrich Syndrome
Interventions: GENETIC: Autologous CD34 positive cells transduced with a lentiviral vector containing human WAS gene
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Manual Therapy and Exercise Training of Diaphragm in Patients With Chronic Neck Pain
Status: COMPLETED
Conditions: Chronic Neck Pain
Interventions: OTHER: Diaphragmatic Stretch Technique|OTHER: Breathing Exercise Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT