pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: REPotrectinib in ROS1-positive Non-small Cell Lung Cancer Patients With Active Brain mEtastasis
Status: NOT_YET_RECRUITING
Conditions: NSCLC|Brain Metastases|ROS1 Gene Rearrangement
Interventions: DRUG: Repotrectinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Pathogenesis of Terson Syndrome and the Role of CSF Tau / Amyloid-ß 40 and 42 in Patients With Aneurysmatic Subarachnoid Hemorrhage
Status: COMPLETED
Conditions: Subarachnoid Hemorrhage|Terson Syndrome|CSF-proteines
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Immunocal® With Exercise Versus Casein With Exercise on Aging Processes in Elderly Persons
Status: COMPLETED
Conditions: Aging|Sarcopenia
Interventions: DIETARY_SUPPLEMENT: Immunocal|DIETARY_SUPPLEMENT: Casein
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Perioperative Oral Decontamination and ImmunoNuTrition (POINT) in Elderly
Status: RECRUITING
Conditions: Postoperative Complications|Pulmonary Complication
Interventions: DIETARY_SUPPLEMENT: immunonutrition supplement of ORAL IMPACT™|OTHER: oral chlorhexidine decontamination
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: To Study Efficacy of Albumin in Cirrhosis With Spontaneous Bacterial Peritonitis at Low Risk for AKI Development
Status: UNKNOWN
Conditions: Liver Cirrhosis|Acute Kidney Injury
Interventions: BIOLOGICAL: Albumin|OTHER: Standard Medical Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy Safety of Granulocyte Colony-stimulating Factor Treatment Children and Adolescents With Muscular Dystrophy
Status: UNKNOWN
Conditions: Increase Muscle Strength in Patients With Muscular Dystrophy
Interventions: DRUG: Granulocyte colony-stimulating factor (Filgrastim)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Search for the Measles Vaccine Virus Excretion in Breast Milk of Breastfeeding Women After Postpartum Vaccination With MMR
Status: COMPLETED
Conditions: Measles|Rubella|Mumps
Interventions: BIOLOGICAL: Combined measles-mumps-rubella (MMR) vaccine - PRIORIX®
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Second Line Induction Therapy and Healthy Diet for Patients With Ulcerative Colitis
Status: COMPLETED
Conditions: Ulcerative Colitis
Interventions: DRUG: Tofacitinib|OTHER: Fast Mimicking Diet|DRUG: Ustekinumab induction|DRUG: Infliximab induction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study of Safety and Tolerability of BPS804 in Patients With Late-stage Chronic Kidney Disease
Status: WITHDRAWN
Conditions: Chronic-kidney Disease Stage 5D on Stable Hemodialysis
Interventions: DRUG: BPS804|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability Trial of Lumateperone in Pediatric Patients With Schizophrenia or Bipolar Disorder
Status: RECRUITING
Conditions: Schizophrenia|Bipolar Disorder
Interventions: DRUG: Lumateperone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Inhibitors of the Proton Pump on Intestinal Transporters
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Dabigatran|DRUG: Rabeprazole and Dabigatran|DRUG: Omeprazole and Dabigatran
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Impact of Cardiac Blood Flow on Cerebral Blood Flow in Patients With Severe Traumatic Brain Injury
Status: UNKNOWN
Conditions: Severe Traumatic Brain Injury With High Cerebral Pressure
Interventions: DRUG: Norepinephrine|DRUG: Dobutamine and norepinephrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Phase 3 Multi-center Study to Assess PET Imaging of Flurpiridaz F 18 Injection in Patients With CAD.
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DRUG: Flurpiridaz F18|DRUG: 99mTechnicium (sestamibi or tetrofosmin)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study Comparing SPP100 (Aliskiren) 150mg to Placebo and to Losartan 50mg in Patients With Mild to Moderate Essential Hypertension
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Aliskiren
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: HRME: Screening for Cervical Cancer and Its Precursors in Low-Resource Settings
Status: COMPLETED
Conditions: Neoplasia of the Uterine Cervix|Cancer Prevention|Cervical Intraepithelial Neoplasia
Interventions: DEVICE: High-Resolution Microendoscopy Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Randomized Study Comparing the Immune Modulation Effect of Ribociclib, Palbociclib, and Abemaciclib in ER+/HER2- EBC
Status: RECRUITING
Conditions: Breast Cancer|Hormone Receptor-positive Breast Cancer|Hormone Therapy
Interventions: DRUG: Palbociclib|DRUG: Ribociclib|DRUG: Abemaciclib|DRUG: Letrozole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Family, Responsibility, Education, Support, and Health for Food Responsiveness
Status: RECRUITING
Conditions: Obesity, Childhood
Interventions: BEHAVIORAL: Regulation of Cues|BEHAVIORAL: Family Based Behavioral Treatment|BEHAVIORAL: Regulation of Cues +|BEHAVIORAL: Health Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pulsatile Perfusion Preservation in Kidney Transplantation From Expanded Criteria Donors
Status: COMPLETED
Conditions: Chronic Renal Failure
Interventions: PROCEDURE: Static incubation|PROCEDURE: Pulsatile perfusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Pragmatic Trial To Determine the Benefit of Exercise Incentives and Corticosteroid Injections in Osteoarthritis of the Knee
Status: COMPLETED
Conditions: Osteoarthritis of the Knee
Interventions: BEHAVIORAL: Social Incentives and Gamification to Promote Exercise|PROCEDURE: Corticosteroid Injection given in A-B order|BEHAVIORAL: No Social Incentive applied|PROCEDURE: Corticosteroid Injection given in B-A order
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Sequentially Combined Vitrectomy, IVTA and Macular Focal Laser Photocoagulation for Diabetic Macular Edema
Status: COMPLETED
Conditions: Diabetic Macular Edema
Interventions: PROCEDURE: vitrectomy|DRUG: intravitreal triamcinolone acetonide|PROCEDURE: macular focal laser photocoagulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Role of Arnica on Muscle Pain Following Eccentric Exercise
Status: COMPLETED
Conditions: Muscles|Exercise|Arnica
Interventions: DRUG: Arnica Montana|DRUG: placebo cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Therapy Associating CPAP and Mandibular Advancement Device in OSA
Status: TERMINATED
Conditions: Obstructive Sleep Apnea Syndrome|Hypertension
Interventions: DEVICE: Continuous Positive Airway Pressure (CPAP) and patient education|DEVICE: Mandibular Advancement Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: InSpace™ System Over Rotator Cuff Repair in Comparison to Repair Alone.
Status: COMPLETED
Conditions: Rotator Cuff Tear
Interventions: DEVICE: InSpace™ system over repair|PROCEDURE: Best Repair of torn Rotator Cuff
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Two Years Follow up of Polyetheretherketone (PEEK) Sub-periosteal Implant Retaining Maxillary Fixed Prosthesis
Status: COMPLETED
Conditions: Mastication Disorder
Interventions: OTHER: Polyetheretherketone (PEEK) Sub-periosteal Implant Retaining Maxillary Fixed Prosthesis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Study of VRC07-523LS, CAP256V2LS, and Vesatolimod, in Early Antiretroviral-treated HIV-1 Clade C-infected Women
Status: ACTIVE_NOT_RECRUITING
Conditions: HIV-1-infection
Interventions: DRUG: Vesatolimod|BIOLOGICAL: VRC07523LS|BIOLOGICAL: CAP256V2LS
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Afatinib and Pembrolizumab for Head and Neck Squamous Cell Carcinoma (ALPHA Study)
Status: COMPLETED
Conditions: Head and Neck Neoplasms
Interventions: DRUG: Afatinib Oral Tablet|DRUG: Pembrolizumab Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Olaparib Dose Escalating Trial + Concurrent RT With or Without Cisplatin in Locally Advanced NSCLC
Status: COMPLETED
Conditions: NSCLC
Interventions: DRUG: Olaparib|DRUG: Cisplatin|RADIATION: Radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endoscopic Placement of Metal Stents in Treating Patients With Cancer- Related Duodenal Obstruction
Status: COMPLETED
Conditions: Colorectal Cancer|Constipation, Impaction, and Bowel Obstruction|Extrahepatic Bile Duct Cancer|Gastric Cancer|Gastrointestinal Carcinoid Tumor|Gastrointestinal Stromal Tumor|Pancreatic Cancer|Quality of Life|Small Intestine Cancer
Interventions: PROCEDURE: bowel obstruction management|PROCEDURE: quality-of-life assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: SUPPORTIVE_CARE
Clinical trial: PERINE : Effect of Prenatal Exposure to Neurotoxicants on the Developing Brain : an MRI Study
Status: COMPLETED
Conditions: Effects of Neurotoxicants on the Brain
Interventions: DEVICE: MRI|OTHER: neuropsychological assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Posterior Capsule Opacification and Frequency of Nd:YAG Treatment and of Two Microincision IOLs: Tecnis ZCB00 and Acrysof SA60AT
Status: COMPLETED
Conditions: Capsule Opacification|Pseudophakia|Cataract
Interventions: PROCEDURE: intraocular lens implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: An Efficacy and Safety Study of Ezetimibe (MK-0653, SCH 58235) in Addition to Atorvastatin Compared to Placebo in Participants With Primary Hypercholesterolemia (MK-0653-013)
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DRUG: Placebo|DRUG: Ezetimibe 10 mg|DRUG: Atorvastatin 10 mg|DRUG: Atorvastatin 20 mg|DRUG: Atorvastatin 40 mg|DRUG: Atorvastatin 80 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Indocyanine Green for Perfusion Assessment of DIEP Flaps
Status: RECRUITING
Conditions: Fat Necrosis
Interventions: DIAGNOSTIC_TEST: Near-infrared fluorescence imaging of perfusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of MabThera Added to Bendamustine or Chlorambucil in Patients With Chronic Lymphocytic Leukemia (MaBLe)
Status: COMPLETED
Conditions: Lymphocytic Leukemia, Chronic
Interventions: DRUG: bendamustine|DRUG: chlorambucil|DRUG: rituximab [MabThera/Rituxan]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I/II Study of Lenalidomide Plus Pembrolizumab in Patients With Solid Tumors With Expansion in Non-small Cell Lung Cancer
Status: TERMINATED
Conditions: Relapsed or Refractory Solid Tumors|Nonsmall Cell Lung Cancer
Interventions: DRUG: Lenalidomide|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Intracanal Cryotherapy on Postoperative Pain Using Two Different Irrigation Systems
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: PROCEDURE: intracanal cryotherapy using needle irrigation and EndoVac system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PhI to Solid Tumors and PhII to Locally Advanced or mTNBC
Status: COMPLETED
Conditions: Solid Tumor|TNBC - Triple-Negative Breast Cancer
Interventions: COMBINATION_PRODUCT: LAE005 + Afuresertib + Nab-Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Subject´s Preference Regarding Hearing Performance and Functionality Using a New Sound Processor
Status: COMPLETED
Conditions: Deafness; Sensoneural Single Sided|Conductive Hearing Loss|Mixed Hearing Loss
Interventions: DEVICE: Investigational device - Sound Processor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Extension Study of Infigratinib in Children With Achondroplasia (ACH)
Status: ENROLLING_BY_INVITATION
Conditions: Achondroplasia
Interventions: DRUG: Infigratinib|DRUG: Infigratinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: OPT-302 With Ranibizumab in Neovascular Age-related Macular Degeneration (nAMD)
Status: ACTIVE_NOT_RECRUITING
Conditions: Neovascular Age-related Macular Degeneration
Interventions: BIOLOGICAL: 2.0 mg OPT-302|BIOLOGICAL: 0.5 mg ranibizumab|PROCEDURE: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PE-1 in the Diagnosis of Pancreatic Exocrine Insufficiency
Status: COMPLETED
Conditions: Pancreatic Exocrine Insufficiency
Interventions: DIAGNOSTIC_TEST: Fecal pancreatic elastase 1 test
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of the Long-term Safety of ABT-089 for Subjects With Mild-to-moderate Alzheimer's Disease Who Participated in the M06-876 Study
Status: TERMINATED
Conditions: Alzheimer's Disease
Interventions: DRUG: ABT-089
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating The Response to Pre-Operative Chemotherapy and/or Radiation Therapy For Rectal Cancer Using Three-Dimension Transrectal Ultrasound
Status: COMPLETED
Conditions: Rectal Cancer
Interventions: OTHER: Transrectal ultrasound 3-D (TRUS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety and Efficacy of Silk Vista and Silk Vista Baby Flow Diverter for Intracranial Aneurysm Treatment
Status: ACTIVE_NOT_RECRUITING
Conditions: Intracranial Aneurysm
Interventions: DEVICE: Intracranial aneurysm treated with Silk vista and silk vista baby
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Cystic Fibrosis Transmembrane Regulator (CFTR) Biomarker Study to Evaluate the Rescue of Mutant CFTR in Patients With Cystic Fibrosis Treated With CFTR-modulators
Status: RECRUITING
Conditions: Cystic Fibrosis
Interventions: DRUG: Treatment with cystic fibrosis transmembrane regulator (CFTR) modualtors Ivacaftor, Lumacaftor-Ivacaftor, Tezacaftor-Ivacaftor, Elexacaftor-Tezacaftor-Ivacaftor
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Cord Blood Transplantation in Patients With Advanced Lymphoid Malignancies
Status: COMPLETED
Conditions: Patients With Advanced Lymphoid Malignancies in the Absence of an HLA Identical or Mismatch Donor
Interventions: OTHER: Cord Blood Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Hyper-CVAD Plus Imatinib Mesylate for Philadelphia-Positive Acute Lymphocytic Leukemia
Status: COMPLETED
Conditions: Leukemia
Interventions: DRUG: Imatinib Mesylate|DRUG: Cyclophosphamide|DRUG: Doxorubicin|DRUG: Vincristine|DRUG: Dexamethasone|DRUG: Methotrexate|DRUG: Cytarabine|DRUG: Mesna|DRUG: G-CSF
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pre-transplant Assessment of Tacrolimus Blood Level Concentration, as a Predictor of Tacrolimus Dose Requirements After Kidney Transplantation
Status: COMPLETED
Conditions: Kidney Transplantation|Transplantation
Interventions: DRUG: tacrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Erector Spinae Plane Block and Transversus Abdominis Plane Block on Postoperative Analgesia After Total Abdominal Hysterectomy
Status: UNKNOWN
Conditions: Uterine Diseases
Interventions: PROCEDURE: erector spinae plane block|PROCEDURE: transversus abdominis plane block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Peropirone Hydrochloride Tablets in the Treatment of Adolescent Bipolar Disorder Depression
Status: UNKNOWN
Conditions: Depressive Disorder
Interventions: DRUG: Perospirone hydrochloride tablets|DRUG: Lithium carbonate + perospirone hydrochloride|DRUG: Lithium Carbonate Pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity nOPV2 With and Without bOPV
Status: COMPLETED
Conditions: Poliomyelitis
Interventions: BIOLOGICAL: Novel monovalent oral poliovirus vaccine type 2 (nOPV2)|BIOLOGICAL: Bivalent oral poliovirus vaccine (bOPV)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Efficacy of Attachment-based Compassion Therapy in Population With Chronic Medical Illness (CUIDA-TEC)
Status: UNKNOWN
Conditions: Chronic Medical Illness
Interventions: BEHAVIORAL: Internet attachment-based compassion therapy (iABCT).
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Dose-escalation Study of RO7567132 as Single Agent and in Combination With Atezolizumab in Participants With Advanced Solid Tumors.
Status: NOT_YET_RECRUITING
Conditions: Cancer-Neoplasms
Interventions: DRUG: RO7567132 and Atezolizumab|DRUG: RO7567132 and Atezolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radicle Calm 2: A Study of Health and Wellness Products on Feelings of Anxiety, Stress, and Health Outcomes
Status: COMPLETED
Conditions: Anxiety|Stress
Interventions: DIETARY_SUPPLEMENT: Calm Active Study Product 1.1 Usage|DIETARY_SUPPLEMENT: Calm Active Study Product 1.2 Usage|DIETARY_SUPPLEMENT: Calm Active Study Product 1.3 Usage|DIETARY_SUPPLEMENT: Placebo Control Form 1|DIETARY_SUPPLEMENT: Placebo Control Form 2|DIETARY_SUPPLEMENT: Calm Active Study Product 2.1 Usage|DIETARY_SUPPLEMENT: Placebo Control Form 3|DIETARY_SUPPLEMENT: Calm Active Study Product 3.1 Usage|DIETARY_SUPPLEMENT: Placebo Control Form 4|DIETARY_SUPPLEMENT: Calm Active Study Product 4.1 Usage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Safety and Effectiveness Study of SQ-Kyrin TMVr System for Degenerated Mitral Regurgitation
Status: ENROLLING_BY_INVITATION
Conditions: Degenerated Mitral Regurgitation
Interventions: DEVICE: transcatheter mitral valve clip delivery system and steerable guide catheter (Shenqi Medical)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cognitive Effects of Theta-burst Stimulation (TBS) in Suspected Non-Alzheimer Disease Pathophysiology (SNAP)
Status: ENROLLING_BY_INVITATION
Conditions: Suspected Non-Alzheimer Disease Pathophysiology (SNAP)
Interventions: DEVICE: active and active TBS|DEVICE: sham and active TBS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Research Study of JNJ-26854165 to Determine the Safety and Dose in Patients With Advanced Stage or Refractory Solid Tumors.
Status: COMPLETED
Conditions: Neoplasms
Interventions: DRUG: JNJ-26854165
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intranasal Versus Intravenous Drug in Painful Procedure for Outpatient Oncologic Participants
Status: UNKNOWN
Conditions: Pediatric Cancer|Analgesia|Procedural Pain
Interventions: DRUG: intranasal dexmedetomidine|DRUG: intranasal fentanyl|DRUG: intravenous ketamine (ketalar®)|DRUG: intravenous midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevalence of Cardiac Amyloidosis Among Patients With a History of Lumbar Spinal Stenosis.
Status: RECRUITING
Conditions: Cardiac Amyloidosis|Spinal Stenosis
Interventions: DIAGNOSTIC_TEST: DPD scintigraphy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: A Randomised, Double-blind, Placebo-controlled, Crossover Study to Evaluate the Effects of a Food Ingredient on Self-reported Stress in Healthy Adults
Status: NOT_YET_RECRUITING
Conditions: Stress
Interventions: OTHER: Calmarell|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bipolar Radiofrequency Ablation Plus Argon Beam Coagulator Ablation for Atrial Fibrillation
Status: UNKNOWN
Conditions: Atrial Fibrillation
Interventions: PROCEDURE: argon beam coagulator ablation|PROCEDURE: bipolar radiofrequency ablation|DEVICE: argon beam coagulator （American，Valleylab）|DEVICE: bipolar radiofrequency (AtricuteTM)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Application of Forced Breath Technique While CPAP Therapy for Apnea Classification
Status: UNKNOWN
Conditions: Sleep Apnea, Obstructive|Sleep Apnea, Central
Interventions: OTHER: CPAP Titration using a Bilevel S/T mode with minimal pressure support and background rate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Whey Protein Supplementation on Postoperative Outcomes After Gynecological Cancer Surgery
Status: RECRUITING
Conditions: Whey Protein|Postoperative Outcomes|Gynecological Cancer Surgery
Interventions: DIETARY_SUPPLEMENT: whey protein supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of AZD1390 and Stereotactic Body Radiotherapy (SBRT) for People With Metastatic Solid Tumor Cancer
Status: RECRUITING
Conditions: Solid Tumor|Metastatic Solid Tumor|Solid Carcinoma|Solid Tumor, Adult|Metastatic Tumor|Metastatic Cancer
Interventions: DRUG: AZD1390|RADIATION: Stereotactic Body Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effect of a Potent Cytochrome P450 (CYP) 3A Inhibitor on Ipatasertib
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Ipatasertib|DRUG: Itraconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Primary Connections for Youth and Families
Status: RECRUITING
Conditions: Substance Use
Interventions: BEHAVIORAL: Standard Screening|BEHAVIORAL: Standard Psychoeducation|BEHAVIORAL: Standard Brief Negotiated Interview (BNI)|BEHAVIORAL: Standard Referral to Treatment (RT)|BEHAVIORAL: Family Screening|BEHAVIORAL: Family Psychoeducation|BEHAVIORAL: Family Brief Negotiated Interview (BNI)|BEHAVIORAL: Family Facilitated Conversation (FC) & Referral to Treatment (RT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Value of Additional Corpus Biopsy for Diagnosis of H Pylori in Atrophic Gastritis. Prospective Non-randomized Study
Status: UNKNOWN
Conditions: Helicobacter Pylori|Gastric Antrum|CORPUS BIOPSIES
Interventions: OTHER: ENDOSCOPIC GASTRIC BIOPSIES FROM ANTRUM AND BODY
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Contrast Enhanced Ultrasound for Evaluation of Reflux Nephropathy
Status: COMPLETED
Conditions: Urinary Tract Infection|Vesicoureteral Reflux
Interventions: DRUG: Sulfur hexafluoride type-a lipid microspheres
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy and Safety of Combination Therapy of Moderate-intensity Statin and Ezetimibe Compared to High-intensity Statin
Status: COMPLETED
Conditions: Cardiovascular Diseases
Interventions: DRUG: Efficacy and safety of combination therapy of moderate-intensity statin and ezetimibe compared to high-intensity statin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Impact of Tranexamic Acid on Red Blood Cell Transfusion in Spinal Surgery
Status: COMPLETED
Conditions: Neurosurgery|Orthopedic Surgery|Red Blood Cell Transfusion
Interventions: DRUG: Tranexamic Acid|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Do Heat and Moisture Exchange Mask Reduce EIB and Cough Severity in Asthma
Status: COMPLETED
Conditions: Asthma, Exercise-Induced|Asthma
Interventions: DEVICE: Heat and Moisture Exchange mask (ColdAvenger® expedition balaclava, USA,|DEVICE: Sham treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Impact of 18F-FDG PET-CT Versus Conventional Staging in the Management of Patients Presenting With Clinical Stage III Breast Cancer
Status: COMPLETED
Conditions: Stage III Breast Cancer (T0N2, T1N2, T2N2, T3N1, 2 or T4)|Stage IIb Breast Cancer (T3N0)
Interventions: OTHER: Whole-body FDG PET-CT alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: MRI-Guided Cryoablation to Alleviate Pain in Head, Neck and Spine
Status: RECRUITING
Conditions: Facet Joints; Degeneration|Neuropathy|Neuralgia
Interventions: PROCEDURE: Cryoablation under image guidance|DEVICE: MRI Seednet Cryotherapy System (Galil Medical)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Trial of Valproic Acid in Patients With Progressive Supranuclear Palsy (Depakine)
Status: COMPLETED
Conditions: Progressive Supranuclear Palsy
Interventions: DRUG: valproic acid|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Effects of Talazoparib on Cardiac Repolarization in Patients With Advanced Solid Tumors
Status: COMPLETED
Conditions: Solid Tumor
Interventions: DRUG: Talazoparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Investigate the Efficacy and Mechanism of ZBP Powder Product in the Treatment of Osteopenia in Patients With Pain.
Status: UNKNOWN
Conditions: Osteopenia
Interventions: OTHER: Placebos|DIETARY_SUPPLEMENT: Zhibai Dihuang powder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Does Oral Propranolol Accelerate Labor Induction/Augmentation With Oxytocin in Nulliparous Women in Abakaliki?
Status: COMPLETED
Conditions: Duration of Labor
Interventions: DRUG: 20mg oral propranolol and oxytocin|DRUG: Oxytocin only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to Investigate the Effect of Inhaling Single Doses of Different Formulations of GW642444M in Asthmatic Patients
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Placebo|DRUG: GW642444|DRUG: Magnesium Stearate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Convalescent Plasma of Covid-19 to Treat SARS-COV-2 a Randomized Doble Blind 2 Center Trial
Status: COMPLETED
Conditions: SARS Pneumonia
Interventions: BIOLOGICAL: Convalescent Plasma of patients with COVID-19|OTHER: placebo (hartmann plus albumine)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Tumor Necrosis Factor in Patients Undergoing Surgery for Primary Cancer or Metastatic Cancer
Status: COMPLETED
Conditions: Adrenocortical Carcinoma|Breast Cancer|Colorectal Cancer|Gastrointestinal Cancer|Kidney Cancer|Liver Cancer|Melanoma (Skin)|Ovarian Cancer|Pancreatic Cancer|Sarcoma
Interventions: BIOLOGICAL: colloidal gold-bound tumor necrosis factor|OTHER: electron microscopy|OTHER: pharmacological study|PROCEDURE: conventional surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Peripheral Nerve Stimulation to Reduce Hypoxic Events
Status: COMPLETED
Conditions: Apnea|Hypoventilation|Hypoxemia
Interventions: DEVICE: Stimulator active device|DEVICE: Stimulator sham Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Sleeper Stretch and Mobilizations With Movement in Patients With Adhesive Capsulitis
Status: COMPLETED
Conditions: Adhesive Capsulitis
Interventions: OTHER: mobilization with movement and conventional therapy|OTHER: sleeper stretch along with conventional therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neurofeedback Enhanced Cognitive Reappraisal Training - Phase 4
Status: NOT_YET_RECRUITING
Conditions: Anxiety|Social Anxiety Disorder|Panic Disorder|Generalized Anxiety Disorder
Interventions: OTHER: Functional magnetic resonance imaging (fMRI) with Veritable-NF|OTHER: fMRI with Sham-NF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Investigate the Effect of Protein in Infant Formula on Insulin Response in Adults
Status: COMPLETED
Conditions: To Compare the Metabolic Effects of Different Infant Milks
Interventions: OTHER: Intact formula|OTHER: Partially hydrolyzed formula|OTHER: High protein formula|OTHER: Human breast milk
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Trial to Assess Haploidentical T-depleted Stem Cell Transplantation in Patients With SCD
Status: RECRUITING
Conditions: HbS Disease|Hemoglobin S Disease|Sickle Cell Anemia|Sickle Cell Disorders|Sickling Disorder Due to Hemoglobin S|Sickle Cell Disease
Interventions: OTHER: TCRα/β+ and CD19+ depleted haploidentical stem cell transplantation|OTHER: Matched sibling donor transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Autologous Bone Marrow Aspirate Concentrate for No-Option Critical Limb Ischemia
Status: COMPLETED
Conditions: Critical Lower Limb Ischemia|Type-2 Diabetes Mellitus
Interventions: BIOLOGICAL: Group A: Intramuscular|BIOLOGICAL: Group B: Intraarterial|BIOLOGICAL: Group C: Intravenous|PROCEDURE: Group D: Surgical endovascular treatment with maximum medicamentous treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: IBI112 in Moderate to Severe Plaque Psoriasis With Randomized Withdrawal and Re-treatment
Status: ACTIVE_NOT_RECRUITING
Conditions: Psoriasis
Interventions: DRUG: IBI112|DRUG: IBI112/placebo|DRUG: IBI112/placebo|DRUG: IBI112|DRUG: IBI112|DRUG: IBI112
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cerebello-Spinal tDCS as Rehabilitative Intervention in Neurodegenerative Ataxia
Status: COMPLETED
Conditions: Ataxia|Spinocerebellar Ataxias|Spinocerebellar Ataxia Type 1|Spinocerebellar Ataxia Type 2|Spinocerebellar Ataxia 3|Multiple System Atrophy|Ataxia With Oculomotor Apraxia|CANVAS
Interventions: DEVICE: Anodal cerebellar and cathodal spinal tDCS|DEVICE: Sham cerebellar and sham spinal tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigating Atezolizumab in Newly Diagnosed ER Positive Breast Cancer Patients According to Their AdipOsity
Status: WITHDRAWN
Conditions: Breast Cancer
Interventions: DRUG: Letrozole|DRUG: Atezolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Bevacizumab in Treating Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia
Status: COMPLETED
Conditions: B-cell Chronic Lymphocytic Leukemia|Refractory Chronic Lymphocytic Leukemia
Interventions: BIOLOGICAL: bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Hibiscus Sabdariffa L. Tea on Blood Pressure
Status: COMPLETED
Conditions: Hypertension
Interventions: BEHAVIORAL: herbal therapy/botanical therapy (Hibiscus sabdariffa)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Osimertinib and Abemaciclib in EGFR Mutant Non-Small Cell Lung Cancer After Osimertinib Resistance
Status: ACTIVE_NOT_RECRUITING
Conditions: Lung Cancer
Interventions: DRUG: Abemaciclib|DRUG: Osimertinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fibromyalgia Syndrome on Patients With Chronic Migraine
Status: COMPLETED
Conditions: Chronic Migraine, Headache|Fibromyalgia Syndrome|Chronic Pain Syndrome|Central Sensitisation|Headache Disorders
Interventions: OTHER: Allodynia, quality of life, sleep, anxiety and depression, disability, and central sensitization|OTHER: Fibromyalgia syndrome
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Influence of Pancreatic Transection With CUSA on Postoperative Pancreatic Fistula Incidence (PANCUT)
Status: RECRUITING
Conditions: Pancreatic Fistula
Interventions: DEVICE: Cavitron ultrasonic surgical aspirator (CUSA)|OTHER: Scalpel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety Study for Cethrin (BA-210) in the Treatment of Acute Thoracic and Cervical Spinal Cord Injuries
Status: COMPLETED
Conditions: Spinal Cord Injury
Interventions: DRUG: Cethrin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exercise Booster Sessions in People With Multiple Sclerosis
Status: RECRUITING
Conditions: Multiple Sclerosis
Interventions: COMBINATION_PRODUCT: Systematic aerobic training|COMBINATION_PRODUCT: Systematic resistance training|COMBINATION_PRODUCT: Aerobic training booster sessions|COMBINATION_PRODUCT: Resistance training booster sessions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Intravenous Immunoglobulin IVIG-F10 in Patients With Primary Immunodeficiencies (PID)
Status: COMPLETED
Conditions: Agammaglobulinemia|IgG Deficiency|Common Variable Immunodeficiency
Interventions: DRUG: Immunoglobulins Intravenous (Human)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prothrombin Complex Concentrate vs Fresh Frozen Plasma in Goal-directed Bleeding Management in Liver Transplantation Surgery
Status: NOT_YET_RECRUITING
Conditions: Liver Diseases
Interventions: BIOLOGICAL: fresh frozen plasma|BIOLOGICAL: prothrombin complex concentrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bone, Immunologic, and Virologic Effects of a Antiretroviral Regimen
Status: COMPLETED
Conditions: HIV-1 Infection
Interventions: DRUG: Darunavir|DRUG: Ritonavir|DRUG: Tenofovir disoproxil fumarate|DRUG: Emtricitabine|DRUG: Placebo for Tenofovir disoproxil fumarate|DRUG: Placebo for Maraviroc|DRUG: Maraviroc
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study Comparing CT Scan and Stress Test in Patients With Known Coronary Artery Disease Hospitalized for Chest Pain
Status: TERMINATED
Conditions: Coronary Artery Disease|Angina Pectoris|Unstable Angina|Acute Coronary Syndrome
Interventions: PROCEDURE: Coronary CT angiography|PROCEDURE: Myocardial perfusion imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Prospective Data Collection on Clinical, Radiological and Patient Reported Outcomes After Pleural Intervention
Status: RECRUITING
Conditions: Pleural Diseases|Pleural Mesothelioma|Pneumothorax|Pleural Effusion|Pleural Infection|Pleural Neoplasms|Pleural Metastases|Pleural Effusion, Malignant|Procedural Complication|Complications, Pulmonary
Interventions: PROCEDURE: Pleural interventions
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: BEACH Trial: Bovine Early Access, Compatibility and Hemostasis Trial
Status: TERMINATED
Conditions: Renal Insufficiency,Chronic
Interventions: DEVICE: Artegraft® Collagen Vascular Graft™ (Artegraft)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Dexmedetomidine and Propofol on Regional Cerebral Tissue Oxygen Saturation
Status: COMPLETED
Conditions: Regional Cerebral Tissue Oxygen Saturation
Interventions: DRUG: Dexmedetomidine Hydrochloride 0.1 MG/ML|DRUG: Propofol 10 MG/ML
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Periodontal Regeneration With Hyaluronic Acid or Enamel Matrix Derivatives
Status: RECRUITING
Conditions: Periodontitis
Interventions: DEVICE: Hyaluronic acid|DEVICE: Enamel matrix derivatives
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Affective Effects of Pre-surgery Opioids: a Randomized, Doubleblind Placebo-controlled Trial
Status: RECRUITING
Conditions: Opioid Use|Affective Symptoms
Interventions: DRUG: Placebo|DRUG: Morphine 2.5 mg i.v.|DRUG: Morphine 5 mg i.v.|DRUG: Morphine 10 mg i.v.|DRUG: Oxycodone 2.5 mg i.v.|DRUG: Oxycodone 5 mg i.v.|DRUG: Oxycodone 10 mg i.v.|DRUG: Fentanyl 0.025 mg i.v.|DRUG: Fentanyl 0.05 mg i.v.|DRUG: Fentanyl 0.1 mg i.v.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Treating Comorbid Depression of Patients With Narcolepsy by Intermittent Theta Burst Stimulation
Status: RECRUITING
Conditions: Narcolepsy
Interventions: DEVICE: "MAGSTIM" reprtitive Transcranial Magnetic Stimulator (rTMS) System|DEVICE: sham control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility of Introducing Midwifery-embodied Community Clinic Model
Status: NOT_YET_RECRUITING
Conditions: Maternal Death|Newborn Morbidity
Interventions: BEHAVIORAL: Midwifery-embodied care
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effect of Activated Charcoal on Rivaroxaban Pharmacokinetics in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: rivaroxaban|DRUG: rivaroxaban and activated charcoal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: FMT in Patients With Recurrent CDI and Ulcerative Colitis: Single Infusion Versus Sequential Approach
Status: RECRUITING
Conditions: Clostridium Difficile|Ulcerative Colitis
Interventions: BIOLOGICAL: single FMT|BIOLOGICAL: sequential FMT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Bioavailability Study of Nicotine Delivered by an Electronic Vapour Product
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: OTHER: EVP unflavoured|OTHER: EVP flavoured|OTHER: Nicotine inhalator|OTHER: Conventional cigarette
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Treatment of Epidemic Keratoconjunctivitis With 2% Povidone-iodine
Status: COMPLETED
Conditions: Viral Conjunctivitis
Interventions: DRUG: 2% povidone-iodine|DRUG: 2% povidone-iodine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of FluBHPVE6E7 in HPV-16 Infected Women
Status: COMPLETED
Conditions: HPV Infection
Interventions: BIOLOGICAL: FluBHPVE6E7
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Resin Salve Versus Honey Treatment in Wound Care
Status: COMPLETED
Conditions: Wound Healing|Wound Infection
Interventions: DEVICE: Abilar 10% resin salve|DEVICE: Activon Tube 25 g
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety and Efficacy of Oral CR845 (Difelikefalin) in Patients With Primary Biliary Cholangitis (PBC) and Moderate-to-Severe Pruritus
Status: TERMINATED
Conditions: Cholestatic Pruritus
Interventions: DRUG: CR845 1.0 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness Verification of Using Hydrogen Inhalation to Improve Fatigue, Pain and Quality of Life in Cancer Patients
Status: RECRUITING
Conditions: Head and Neck Cancer|Quality of Life|Pain|Sleep|Inhalation; Gas
Interventions: OTHER: Hydrogen Inhalation|OTHER: Ordinary Air Inhalation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Investigation of Nicotine Seeking Behavior in Current Smokers
Status: COMPLETED
Conditions: Cigarette Smoking
Interventions: DRUG: Yohimbine Hydrochloride|DRUG: Hydrocortisone|DRUG: Lactose Monohydrate Powder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE