pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Recurrent Urinary Tract Infections and Heparin (RUTIH Trial)
Status: RECRUITING
Conditions: Recurrent Urinary Tract Infections
Interventions: DRUG: Intravesical Heparin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Allium Sativum Oil and Turmeric Gel as Alternative Non-vital Pulpotomy Medicaments in Primary Teeth.
Status: COMPLETED
Conditions: Non Vital Teeth
Interventions: DRUG: Allium Sativum Oil|DRUG: Turmeric Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Standard Therapy and TIPS for Moderate to High-risk Esophageal and Gastric Variceal Bleeding
Status: RECRUITING
Conditions: Portal Hypertension
Interventions: PROCEDURE: Endoscopy+NSBBs|PROCEDURE: Transjugular intrahepatic portosystemic shunt
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Fimasartan Plus Amlodipine on Hemodynamic Parameters and Arterial Stiffness in Patients With Hypertension
Status: UNKNOWN
Conditions: Arterial Hypertension
Interventions: COMBINATION_PRODUCT: Fimasartan plus amlodipine besylate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessing Immune Function in Young Patients With Cytopenia That Did Not Respond to Treatment
Status: COMPLETED
Conditions: Dyskeratosis Congenita|Fanconi Anemia|Myelodysplastic Syndromes|Pearson Marrow-pancreas Syndrome|Shwachman-diamond Syndrome
Interventions: GENETIC: polymerase chain reaction|OTHER: flow cytometry|OTHER: immunologic technique|PROCEDURE: biopsy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phase 1 TheraSphere + Everolimus With Neuroendocrine Tumors (NETs) + Liver Only or Liver Dominant Disease
Status: WITHDRAWN
Conditions: Liver Cancer
Interventions: OTHER: TheraSphere|DRUG: Everolimus|OTHER: Phone Call
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intramedullary Calcium Sulfate Antibiotic Depot
Status: RECRUITING
Conditions: Open tíbia Fracture|Osteomyelitis Tibia|Tibial Fractures
Interventions: DRUG: Vancomycin Hydrochloride|DRUG: Gentamicin|OTHER: Standard Intramedullary Nail
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effects of Slider Versus Tensioners Nerve Gliding in Cervical Radiculopathy.
Status: COMPLETED
Conditions: Cervical Radiculopathy
Interventions: OTHER: Slider Nerve Gliding Technique along with Mulligan Spinal Mobilization Technique|OTHER: Tensioners Nerve Gliding Technique along with Mulligan Spinal Mobilization Technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Acute Normovolemic Hemodilution on Serum-creatinine Concentration in Cardiac Surgery
Status: COMPLETED
Conditions: Mitral Regurgitation|Mitral Stenosis|Tricuspid Regurgitation
Interventions: PROCEDURE: Acute normovolemic hemodilution (ANH)|DRUG: hydroxyethyl starch (HES 130/0.6)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Premarin Versus Toviaz for Treatment of Overactive Bladder
Status: UNKNOWN
Conditions: Overactive Bladder
Interventions: DRUG: Toviaz|DRUG: Premarin|DRUG: Placebo cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Bevacizumab (Avastin) in Combination With Chemotherapy in Participants With Metastatic Cancer of the Colon or Rectum
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: 5-Fluorouracil|DRUG: Bevacizumab|DRUG: Irinotecan|DRUG: Oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Decreasing Environmental Impact and Costs of Using Inhalational Anesthetic With a Carbon Dioxide Membrane Filter System
Status: UNKNOWN
Conditions: Anesthesia|Inhalation; Vapor
Interventions: DEVICE: Memsorb|DRUG: Chemical granulate absorber
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Randomized Trial of NSAID vs Placebo Prior to Ureteral Stent Removal
Status: COMPLETED
Conditions: Disorder of Urinary Stent|Ureteral Spasm|Ureteropelvic Junction Obstruction|Urolithiasis
Interventions: DRUG: Ibuprofen|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Treatment With Fixture Microthread™ in Patients With Poor Bone Quality and no Teeth in the Upper Jaw, When Using Two-Stage Surgery
Status: TERMINATED
Conditions: Jaw, Edentulous|Poor Bone Quality
Interventions: DEVICE: Fixture MicroThread (Micro-Macro)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Surgical Approaches for Crohn's Disease Recurrence
Status: RECRUITING
Conditions: Endoscopic Recurrence Rate|After Ileocolic Crohn 's Disease Surgery
Interventions: PROCEDURE: mesentery-guided resection margin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Application of BOPPPS（Bridge-in,Objective,Pre-assessment,Participatory Learning,Post-assessment,Summary） Model in the Ward Rounds of Nurses' Standardized Training
Status: ACTIVE_NOT_RECRUITING
Conditions: Standardized Training
Interventions: OTHER: Training by BOPPPS Teaching Model|OTHER: Training Regularly
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Emdogain Minimally Invasive Surgical Technique
Status: COMPLETED
Conditions: Periodontitis
Interventions: PROCEDURE: Scaling and root planing|PROCEDURE: Scaling and root planing without Emdogain|DEVICE: Emdogain application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Penicillin and Metronidazole in Treatment of Peritonsillar Abscess
Status: COMPLETED
Conditions: Peritonsillar Abscess
Interventions: DRUG: penicillin and metronidazole in peritonsillar abscess
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Olanzapine Against Delayed Nausea and Vomiting in Women Receiving Carboplatin Plus Paclitaxel
Status: UNKNOWN
Conditions: Nausea|Vomiting
Interventions: DRUG: Olanzapine|DRUG: Palonosetron, Dexamethasone, Carboplatin, Paclitaxel, Olanzapine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Remote Ischemic Preconditioning in Cardiac Surgery
Status: UNKNOWN
Conditions: Ischemia Reperfusion Injury
Interventions: PROCEDURE: remote ischemic preconditioning|PROCEDURE: Sham remote ischemic preconditioning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Topical Steroids Alone or Associated With Methotrexate in Bullous Pemphigoid
Status: COMPLETED
Conditions: Bullous Pemphigoid
Interventions: DRUG: clobetasol propionate + Methotrexate|DRUG: clobetasol propionate alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of FDOPA-PET/MRI in Pediatric Patients With CNS Tumors
Status: COMPLETED
Conditions: Astrocytoma, Oligoastrocytoma, Mixed|Ganglioneuroma|Glioma|Ganglioglioma|Glioblastoma Multiforme Glioma
Interventions: DRUG: Irinotecan|DRUG: Bevacizumab|DEVICE: FDOPA-PET/MRI imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability of Intravitreal VEGF Trap Formulations in Subjects With Neovacular AMD
Status: COMPLETED
Conditions: Neovascular Age Related Macular Degeneration
Interventions: DRUG: VEGF Trap|BIOLOGICAL: VEGF Trap
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 1b Study of VERVE-201 in Patients With Refractory Hyperlipidemia
Status: NOT_YET_RECRUITING
Conditions: Hypercholesterolemia
Interventions: DRUG: VERVE-201
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aripiprazole for Bipolar Disorder and Alcohol Use Disorder
Status: COMPLETED
Conditions: Bipolar Disorder|Alcoholism|Alcohol Abuse
Interventions: DRUG: Aripiprazole|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Post Approval Study2: Hintermann Series H3 Total Ankle Replacement System
Status: RECRUITING
Conditions: Osteoarthritis Ankle|Post-Traumatic Osteoarthritis of Ankle|Osteoarthritis of Ankle Secondary to Inflammatory Arthritis (Disorder)
Interventions: DEVICE: Hintermann Series H3 Total Ankle Replacement System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Polyclonal Regulatory T Cells (PolyTregs) for Pemphigus
Status: TERMINATED
Conditions: Pemphigus Foliaceus|Pemphigus Vulgaris
Interventions: BIOLOGICAL: Cohort 1: 1.0 x 10^8 PolyTregs|BIOLOGICAL: Cohort 2: 2.5x10^8 PolyTregs
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preoperative CRT With or Without Induction Chemotherapy for Rectal Cancer With Liver Metastases
Status: UNKNOWN
Conditions: Rectal Cancer|Liver Metastases
Interventions: DRUG: Capecitabine, Oxaliplatin|RADIATION: Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cisplatin-Based Chemotherapy and/or Surgery in Treating Young Patients With Adrenocortical Tumor
Status: COMPLETED
Conditions: Stage I Adrenal Cortical Carcinoma AJCC v7|Stage II Adrenal Cortical Carcinoma AJCC v7|Stage III Adrenal Cortical Carcinoma AJCC v7|Stage IV Adrenal Cortical Carcinoma AJCC v7
Interventions: DRUG: Cisplatin|PROCEDURE: Conventional Surgery|DRUG: Doxorubicin Hydrochloride|DRUG: Etoposide|BIOLOGICAL: Filgrastim|DRUG: Mitotane|BIOLOGICAL: Pegfilgrastim
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Modulation of Circulating Levels of the Ketone Body 3-hydroxybutyrate in Patients With Type 2 Diabetes and Heart Failure With Preserved Ejection Fraction: Metabolic Effects. (KETO-HFpEF-Metabolic)
Status: COMPLETED
Conditions: Heart Failure With Preserved Ejection Fraction|Diabetes Mellitus, Type 2|Ketonemia
Interventions: DIETARY_SUPPLEMENT: Ketone ester|DIETARY_SUPPLEMENT: Placebo drink
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PIK3CA/PTEN-altered Advanced Breast Cancer Treated With MEN1611 Monotherapy or in Combination With Eribulin
Status: RECRUITING
Conditions: Breast Cancer|Advanced Breast Cancer|Metastatic Breast Cancer
Interventions: DRUG: MEN1611|DRUG: Eribulin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety and Pharmacokinetics of Efmarodocokin Alfa in Combination With Standard of Care in Participants Undergoing Allogeneic Hematopoietic Stem Cell Transplantation
Status: COMPLETED
Conditions: Acute Graft-versus-host Disease
Interventions: DRUG: Efmarodocokin Alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study Investigating Pain Following Single-port or Multi-port Video Assisted Thoracoscopic Surgery
Status: WITHDRAWN
Conditions: Pain, Postoperative
Interventions: PROCEDURE: Single port VATS|DRUG: Paracetamol|DRUG: Diclofenac|DEVICE: Camera (5mm diameter 30 degree videothoracoscope)|DEVICE: Forceps grasper|DRUG: 0.25% Levobupivicaine intercostal nerve block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Autologous Adipose Derived Stromal Vascular Fraction for Musculoskeletal Conditions
Status: NOT_YET_RECRUITING
Conditions: Knee Osteoarthritis
Interventions: PROCEDURE: stromal vascular fraction injection in the osteoarthritic knee
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effect of Supplementary Vitamin D in Patients With Diabetes Mellitus and Pulmonary Tuberculosis
Status: UNKNOWN
Conditions: Type 2 Diabetes Mellitus|Pulmonary Tuberculosis
Interventions: DIETARY_SUPPLEMENT: Vitamin D|DIETARY_SUPPLEMENT: Calcium|DIETARY_SUPPLEMENT: Placebo Vit D|DIETARY_SUPPLEMENT: Placebo Calcium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: RAM-Based Virtual Reality Glasses and Adaptation, Satisfaction, Well-Being in the Elderly
Status: COMPLETED
Conditions: Nursing|Evidence-Based Nursing
Interventions: BEHAVIORAL: Experimental RAM-based virtual reality glasses|OTHER: pre-post test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: An Investigational Immuno-Therapy Study to Determine the Safety and Effectiveness of Nivolumab and Daratumumab in Patients With Multiple Myeloma
Status: COMPLETED
Conditions: Non-Hodgkin's Lymphoma|Hodgkin Lymphoma|Multiple Myeloma
Interventions: BIOLOGICAL: Nivolumab|BIOLOGICAL: Ipilimumab|BIOLOGICAL: Lirilumab|BIOLOGICAL: Daratumumab|DRUG: Pomalidomide|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Of Efficacy And Safety Of Fesoterodine In Vulnerable Elderly Subjects With Overactive Bladder
Status: COMPLETED
Conditions: Overactive Bladder
Interventions: DRUG: Fesoterodine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Partnered Evaluation to Improve the Identification and Management of Functional Impairment and Frailty Among Older Veterans in Primary Care Settings
Status: RECRUITING
Conditions: Functional Impairment|Frailty
Interventions: OTHER: Screening intervention|OTHER: Standard bundle of implementation strategies|OTHER: Enhanced bundle of implementation strategies
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Comparison of Vehicle Delivery Depth Using the NovoFine® 5 mm Needle With or Without a Skin Fold and Inserted at Either 45 or 90 Degrees
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: PROCEDURE: Sterile air injection|PROCEDURE: Placebo injection|DEVICE: Novofine needle
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Cranial Stimulation and Acupuncture on Pain, Functional Capability and Cerebral Function in Osteoarthritis
Status: COMPLETED
Conditions: Osteoarthritis, Knee|Chronic Pain
Interventions: OTHER: tDCS and EAC sham|OTHER: tDCS sham and EAC sham|OTHER: tDCS sham and EAC|OTHER: tDCS and EAC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Gefitinib in Treating Patients With Newly Diagnosed Glioblastoma Multiforme
Status: COMPLETED
Conditions: Adult Giant Cell Glioblastoma|Adult Glioblastoma|Adult Gliosarcoma
Interventions: DRUG: gefitinib|OTHER: pharmacological study|OTHER: laboratory biomarker analysis|OTHER: questionnaire administration|PROCEDURE: quality-of-life assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prolonging the Duration of Peripheral Venous Catheters in Cystic Fibrosis People
Status: TERMINATED
Conditions: Cystic Fibrosis|Phlebitis
Interventions: PROCEDURE: regular dilution of antibiotic in NS|PROCEDURE: higher dilution of antibiotic in NS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Acceptability Study of Nutritional Supplements in Hospitalized Elderly Patients
Status: COMPLETED
Conditions: Malnutrition
Interventions: DIETARY_SUPPLEMENT: Fortimel Compact Protein|DIETARY_SUPPLEMENT: Fortimel Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Comparing Perclose to Statseal With Perclose in Transcatheter Aortic Valve Replacement Arteriotomy Closure
Status: COMPLETED
Conditions: Arterial Occlusion|Cardiovascular Diseases|Hematoma
Interventions: DEVICE: Perclose|DEVICE: Statseal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SOLSTICE: Combination Therapy for the Treatment of Chronic Hepatitis D Infection.
Status: RECRUITING
Conditions: Hepatitis D, Chronic
Interventions: DRUG: VIR-2218|DRUG: VIR-3434|DRUG: NRTI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Thiazolidinedione Intervention With Vitamin D Evaluation
Status: TERMINATED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: pioglitazone|DRUG: rosiglitazone|DRUG: placebo|DIETARY_SUPPLEMENT: Vitamin D|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Zanubrutinib Combined With R-CHOP in the Treatment of Newly Diagnosed DLBCL With p53 Protein Expression
Status: RECRUITING
Conditions: Diffuse Large B Cell Lymphoma
Interventions: DRUG: Zanubrutinib plus RCHOP
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Primary Pain Palliation in Bone Metastases Treated With Magnetic Resonance-guided Focused Ultrasound
Status: UNKNOWN
Conditions: Secondary Malignant Neoplasm of Bone
Interventions: PROCEDURE: MRgFUS
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Combination of Preoperative MRI and SLN in the Surgical Management of CC and EC
Status: ENROLLING_BY_INVITATION
Conditions: Sentinel Lymph Node Biopsy|MRI
Interventions: DRUG: ICG/ blue dye
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Paclitaxel i.v. Plus Cisplatin i.p for NACT in Patients With Advanced Ovarian Cancer
Status: UNKNOWN
Conditions: Epithelial Carcinoma, Ovarian|Neoadjuvant Chemotherapy
Interventions: DRUG: cisplatin i.p.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study in Healthy Volunteers to Evaluate the Application of Stable Isotope Approach to Reduce Number of Subjects Needed for PK Studies
Status: COMPLETED
Conditions: Metabolic, Cardiovascular
Interventions: DRUG: Tab carvedilol 25 mg|DRUG: Tab carvedilol 6.25 mg|DRUG: Powder carvedilol up to 2.5 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Amino Acid Infusion in Mothers Before and During Cesarean Delivery
Status: COMPLETED
Conditions: Hypothermia
Interventions: DRUG: Amino acid solution|DRUG: Ringer's lactate solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of the Effect of Everolimus Immunosuppressive Combination Therapies on Renal Function When Used as a Maintenance Treatment for Liver Transplant Patients.
Status: WITHDRAWN
Conditions: Liver Transplantation
Interventions: DRUG: TAC withdrawal|DRUG: Everolimus with reduced TAC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Prospective, Randomized Clinical Trial of PRP Concepts Fibrin Bio-Matrix in Chronic Non-Healing Pressure Ulcers
Status: UNKNOWN
Conditions: Pressure Ulcer
Interventions: DEVICE: PRP Concepts Fibrin Bio-Matrix|OTHER: Usual and Customary Practice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Improved Oral Health and Dental Care in Children With Congenital Heart Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Oral Health|Dental Caries
Interventions: BEHAVIORAL: educational intervention using motivational interviewing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: CampETEC Hyperimmune Bovine Colostrum (HBC)
Status: ACTIVE_NOT_RECRUITING
Conditions: Healthy Volunteer
Interventions: BIOLOGICAL: CampETEC HBC product|BIOLOGICAL: ProMilk 85|BIOLOGICAL: C. jejuni CG8421 Challenge strain
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Effectiveness of Correcting Refractive Error With Ready-made Spectacles
Status: COMPLETED
Conditions: Myopia|Hyperopia|Astigmatism
Interventions: DEVICE: Ready-made spectacles|DEVICE: Spectacles
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Open-label Trial to Compare Efficacy and Tolerance of Corticosteroids and IVIg
Status: COMPLETED
Conditions: Demyelinating Polyneuropathy
Interventions: DRUG: Immunoglobulin perfusion|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Glucose Homeostasis and Apple Polyphenols
Status: TERMINATED
Conditions: PreDiabetes|Impaired Glucose Tolerance|Glucose Metabolism Disorders
Interventions: DIETARY_SUPPLEMENT: Apple Polyphenols|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of the Pharmacokinetics, Pharmacodynamics, and Safety of Opicapone in Subjects With Parkinson's Disease Taking Levodopa.
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: DRUG: Opicapone|DRUG: Carbidopa Levodopa
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The OPTIMAL Randomized Controlled Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Left Main Coronary Artery Stenosis
Interventions: DEVICE: IVUS guided Percutaneous Coronary Intervention|DEVICE: QCA guided Percutaneous Coronary Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Safety, and Tolerability of AVP-786 for the Treatment of Residual Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: AVP-786|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Therapy for Rejuvenation of the Lower Face and Neck
Status: UNKNOWN
Conditions: Laxity; Skin
Interventions: DEVICE: Ultherapy|DEVICE: Xeomin|DEVICE: Belotero Balance|DEVICE: Dilute Radiesse|OTHER: Neocutis Micro Firm Face and Neck Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Lidocaine/Dexamethasone on the Success of IANB
Status: COMPLETED
Conditions: Local Anesthesia
Interventions: DRUG: 2% lidocaine with 1:80,000 epinephrine|DRUG: Dexamethasone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Study Comparing Coristina® D to Resfenol® in the Symptomatic Treatment of Common Cold
Status: UNKNOWN
Conditions: Cold
Interventions: DRUG: Resfenol|DRUG: Coristina d
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: First-line Maintenance Treatment With Fluzoparib Plus Bevacizumab in Advanced BRCA Wild Type Ovarian Cancer
Status: NOT_YET_RECRUITING
Conditions: Ovarian Cancer|High Grade Serous Adenocarcinoma of Ovary|High Grade Endometrioid Ovarian Cancer|Primary Peritoneal Cancer|Fallopian-tube Cancer
Interventions: DRUG: Fluzoparib Capsules|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of PF-299804 (Dacomitinib), a Pan-HER Irreversible Inhibitor, in Patients With Recurrent Glioblastoma With EGFR Amplification or Presence of EGFRvIII Mutation. A Phase II CT.
Status: COMPLETED
Conditions: Glioblastoma|Brain Tumor, Recurrent
Interventions: DRUG: PF-299804 (Dacomitinib)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Compare the Efficacy of Aloe Vera Mouthwash With Non- Alcoholic Chlorhexidine Mouthwash on Periodontal Diseases
Status: COMPLETED
Conditions: Periodontal Diseases
Interventions: DRUG: Active Comparator:Aloe Vera mouthwash|DRUG: Active Comparator:Chlorhexidine mouthwash
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial for Valuation of the Effectiveness of Lactoferrine in the Prevention of Sepsis in New Premature Born. Bimonitorization of the Antinflammatory Mechanisms, Antioxidants and the Intestinal Microbiote.
Status: UNKNOWN
Conditions: SEPSIS SYNDROME
Interventions: DIETARY_SUPPLEMENT: Enteral administration of bovine lactoferrin (bLf)|OTHER: Enteral administration of placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Oral Valganciclovir Versus Valacyclovir
Status: COMPLETED
Conditions: Chronic Lymphocytic Leukemia|Leukemia
Interventions: DRUG: Valganciclovir|DRUG: Valacyclovir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Double-Blind Study on Adjunctive Use of PEMF in the Treatment of 5th Metatarsal Non-Union Fractures
Status: TERMINATED
Conditions: Nonunion of Fracture of Fifth Metatarsal
Interventions: DEVICE: EBI Bone Healing System|DEVICE: Placebo Device|PROCEDURE: Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Effect of Spinal Cord Stimulation Frequency on Fast-Acting Sub-perception Therapy (FAST) for Chronic Pain
Status: UNKNOWN
Conditions: Neuropathic Low Back Pain
Interventions: PROCEDURE: Spinal cord stimulator implant|DIAGNOSTIC_TEST: Healing period|DEVICE: WaveWriter™ Alpha Spinal Cord Stimulator (SCS) system
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: TMC278-TiDP6-C121: Drug-drug Interaction Trial to Investigate the Potential Interaction Between TMC278 25 mg Daily and Methadone, at Steady State.
Status: COMPLETED
Conditions: HIV
Interventions: DRUG: TMC278
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Inhibition of α-synuclein Cell-cell Transmission by NMDAR Blocker, Memantine
Status: UNKNOWN
Conditions: Parkinson Disease
Interventions: DRUG: Memantine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mitoxantrone Hydrochloride Liposome Injection, Bortezomib and Dexamethasone in the Treatment of R/R MM
Status: UNKNOWN
Conditions: Relapsed or Refractory Multiple Myeloma
Interventions: DRUG: Mitoxantrone Hydrochloride Liposome injection|DRUG: Bortezomib for Injection|DRUG: Dexamethasone Acetate Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Association of Functional Changes in the Brain and the Perception of Pain in Patients With Chronic Inflammatory Bowel Diseases (IBD)
Status: COMPLETED
Conditions: Inflammatory Bowel Disease
Interventions: DEVICE: Transcranial direct current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect on the Nutritional and Inflammatory Status of Docosahexaenoic Acid (DHA) and Eicosapentaenoic Acid (EPA)- Containing Supplement in Patients With Advanced Lung Cancer
Status: UNKNOWN
Conditions: Lung Cancer
Interventions: OTHER: Nutritional Assessment|DIETARY_SUPPLEMENT: EPA-DHA arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: To Demonstrate the Relative Bioequivalence of Cefdinir and Omnicel 250mg/5 ml Oral Suspension Fasting Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Cefdinir 250 mg/5 ml Oral Suspension (Sandoz, Austria)|DRUG: Omnicef 250 mg/5 ml Oral Suspension of Cefdinir (Abbot Laboratories, USA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of PBI-200 With Ritonavir or Cobicistat in Healthy Volunteers
Status: COMPLETED
Conditions: Drug-drug Interaction
Interventions: DRUG: PBI-200 Tablet|DRUG: Ritonavir Oral Tablet|DRUG: Cobicistat Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Telerehabilitation Protocols With Digital and Robotic Tools for People With Chronic Neurological Disorders
Status: NOT_YET_RECRUITING
Conditions: Post-stroke|Parkinson Disease|Multiple Sclerosis
Interventions: DEVICE: medical device "Homing" (TecnoBody); medical device "Icone" (Heaxel)|BEHAVIORAL: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Influence of SARS-CoV-2 Lifestyle Changes on Non-alcoholic Fatty Liver Disease Evolution
Status: COMPLETED
Conditions: Non-Alcoholic Fatty Liver Disease
Interventions: BEHAVIORAL: SUPERIMPOSED SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS-2 (SARS-CoV-2) LIFESTYLE CHANGES
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of HFOT on Exercise Performance in Patients With COPD. A Randomized, Controlled Trial.
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: COMBINATION_PRODUCT: High-flow oxygen therapy (HFOT)|COMBINATION_PRODUCT: Low-flow oxygen therapy (LFOT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ephedrine vs Phenylephrine - ECG Changes
Status: TERMINATED
Conditions: Spinal Anesthesia|Pregnancy
Interventions: DRUG: Phenylephrine|DRUG: Ephedrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Myopic Monovision: EDOF vs. Monofocal IOL
Status: UNKNOWN
Conditions: Cataract
Interventions: DEVICE: enhanced depth of focus IOL|DEVICE: monofocal IOL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Auricular Press Needle on Improvement of Patient Health Questionnaire-9 (PHQ-9) and Heart Rate Variability (HRV) Patient With Depression Symptoms in Chronic Pain
Status: NOT_YET_RECRUITING
Conditions: Depression Symptoms|Chronic Pain
Interventions: DEVICE: Plesterin|DEVICE: Press needle acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Xtract™ Aspiration Catheter Registry Study
Status: COMPLETED
Conditions: Fresh Soft Emboli or Thrombi in the Arteries.
Interventions: DEVICE: Xtract Aspiration Catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Renoprotective Effects of Dapagliflozin Versus Pentoxiphylline in Chronic Kidney Disease Patients
Status: RECRUITING
Conditions: Chronic Kidney Diseases
Interventions: DRUG: Dapagliflozin 10mg Tab|DRUG: Pentoxifylline 400 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dementia Caregiver Chronic Grief Management: A Live Online Video Intervention
Status: COMPLETED
Conditions: Chronic Grief|Dementia Family Caregivers
Interventions: BEHAVIORAL: Chronic Grief Management Intervention-Video
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Liver Transplantation for Unresectable GIST Liver Metastases
Status: NOT_YET_RECRUITING
Conditions: Liver Diseases|Liver Cancer|Liver Metastases|Liver Neoplasms|Liver Mass|Liver Carcinoma|Liver Transplant; Complications|Liver Transplant Disorder|GIST|GIST, Malignant|Gastrointestinal Stromal Tumors|Gastrointestinal Stromal Tumor of Duodenum|Gastrointestinal Stromal Tumor of Rectum|Gastrointestinal Stromal Tumor of Other Sites|Gastrointestinal Stromal Tumor, Unspecified Site|Gastrointestinal Stromal Tumor of Stomach|Gastrointestinal Stromal Tumor of Esophagus (Disorder)|Gastrointestinal Stromal Tumor by AJCC V8 Stage|Gastrointestinal Stromal Tumor, Malignant|Gastrointestinal Stromal Tumor (GIST) of the Gastrointestinal Tract|Gastrointestinal Stromal Tumor of Small Intestine (Disorder)|Gastrointestinal Stromal Tumor of Large Intestine (Disorder)|Metastases to Liver|Metastatic Liver Cancer|Metastasis|Metastases|Liver Transplantation|Transplant Oncology
Interventions: PROCEDURE: Liver Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intestinal Microflora in Lung Cancer After Chemotherapy
Status: COMPLETED
Conditions: Lung Cancer|Effects of Chemotherapy|Tumor Immunity|Malnutrition
Interventions: DRUG: Probiotics|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Impact of Palmitoylethanolamide (PEA) in the Management of Oro-facial Pain
Status: RECRUITING
Conditions: Oral-facial Pain
Interventions: DIETARY_SUPPLEMENT: Palmitoyletinolamide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study Of Costs Realized After Percutaneous Coronary intervenTion Employing Same Day Discharge
Status: TERMINATED
Conditions: Coronary Artery Disease
Interventions: BEHAVIORAL: Same day discharge|BEHAVIORAL: Overnight Stay
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effect of Bilateral Quadratus Lumborum Block for Pain Relief in Patients With Cesarean Section
Status: COMPLETED
Conditions: Caesarean Section|Spinal Anesthesia|Quadratus Lumborum Block|Analgesia
Interventions: DRUG: Intrathecal morphine|DRUG: Bilateral Quadratus Lumborum Block|DRUG: Intrathecal morphine with bilateral Quadratus Lumborum Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Replacing Buried Sutures With Tissue Adhesive on Aesthetic Outcome of Surgical Wounds.
Status: TERMINATED
Conditions: Surgical Wound
Interventions: PROCEDURE: Closure of surgical wounds using buried sutures or tissue adhesive on aesthetic outcome.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Pomalidomide for Myelofibrosis Patients
Status: COMPLETED
Conditions: Polycythemia Vera|Thrombocythemia
Interventions: DRUG: CC-4047|DRUG: Prednisone|DRUG: CC-4047
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Prontosan Solution on Chronic Ulcers
Status: COMPLETED
Conditions: Pressure Ulcer|Chronic Wound Care|Wound Cleansing
Interventions: DEVICE: Prontosan wound irrigation solution|DRUG: Isotonic solution (saline or lactated ringer)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Left Ventricular Dyssynchrony in Multipole Pacing
Status: COMPLETED
Conditions: Heart Failure，Congestive
Interventions: DEVICE: Different programming of a CRT defibrillator
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Evaluate a Single Intravenous (IV) Dose Using a New Manufactured Clone and Single Ascending Doses of Subcutaneous (SC) Injections
Status: COMPLETED
Conditions: Pharmacokinetics of ASP2408|Healthy Subjects
Interventions: DRUG: ASP2408|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Immunity to Yellow Fever in HIV-infected Patients 10 Years After a Primary Anti-yellow Fever Vaccination
Status: NOT_YET_RECRUITING
Conditions: HIV Infections|Yellow Fever
Interventions: BIOLOGICAL: Yellow fever vaccination (STAMARIL)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Phase II MULTICENTRE Trial of Needle Based Laser Confocal Endomicroscopy of Cystic and Solid Tumours of the Pancreas
Status: COMPLETED
Conditions: Pancreatic Cyst|Serous Cystadenoma|Intraductal Papillary Mucinous Neoplasm|Cystadenoma, Mucinous
Interventions: DEVICE: AQ-Flex 19 probe (Mauna Kea Technologies, Paris)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study Investigating the Efficacy and Safety of LBL-007 Plus Tislelizumab in Combination With Bevacizumab Plus Fluoropyrimidine Versus Bevacizumab Plus Fluoropyrimidine in Participants With Unresectable or Metastatic Colorectal Cancer
Status: RECRUITING
Conditions: Unresectable or Metastatic Microsatellite Stable/Mismatch Repair Proficient Colorectal Cancer
Interventions: DRUG: LBL-007|DRUG: LBL-007|DRUG: LBL-007|DRUG: Tislelizumab|DRUG: Tislelizumab|DRUG: Bevacizumab biosimilar|DRUG: Bevacizumab biosimilar|DRUG: Capecitabine|DRUG: 5-Fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: AI-powered Chatbot vs. Human Counselors in Smoking Cessation
Status: NOT_YET_RECRUITING
Conditions: Smoking Cessation|Mobile Health
Interventions: BEHAVIORAL: 5A's/5R's advice|OTHER: Brief leaflet on health warning and smoking cessation|OTHER: Self-help smoking cessation booklet|BEHAVIORAL: AI-powered chatbot support|BEHAVIORAL: Counselor individual support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Single-arm Phase II Clinical Study of the Efficacy and Safety of Camrelizumab Combined With GEMOX for Unresectable GBCs
Status: RECRUITING
Conditions: Unresectable Gallbladder Cancer
Interventions: DRUG: Camrelizumab plus GEMOX
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Efficiency of Propioceptive Study According to Radiological Stages in Patients With Knee Osteoarthritis
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: OTHER: Proprioceptive training
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Omeprazole 20 mg in Patients With Laryngopharyngeal reﬂux and Comorbid Chronic Rhinosinusitis
Status: COMPLETED
Conditions: Laryngopharyngeal Reflux|Chronic Rhinosinusitis (Diagnosis)
Interventions: DRUG: Omeprazole 20mg|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Evaluate Clinical Impact of PGx-Guided Treatment for Patients Undergoing Elective Spinal Surgical Procedures
Status: TERMINATED
Conditions: Acute Pain|Surgery
Interventions: GENETIC: NeuroIDgenetix Test Panel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: HEART Camp: Promoting Adherence to Exercise in Patients With Heart Failure
Status: COMPLETED
Conditions: Heart Failure
Interventions: BEHAVIORAL: Enhanced Usual Care Group|BEHAVIORAL: HEART Camp (HC) Intervention Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Neoadjuvant Sunitinib Treatment for Metastatic Clear Cell Renal Cell Carcinoma (RCC)
Status: UNKNOWN
Conditions: Clear Cell Renal Cell Carcinoma|Metastasis
Interventions: DRUG: Sunitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aripiprazole Associated With Methylphenidate in Children and Adolescents With Bipolar Disorder and ADHD
Status: COMPLETED
Conditions: Bipolar Disorder|Attention Deficit Hyperactivity Disorder
Interventions: DRUG: Aripiprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Effects of Cervical Manipulation and Mobilization on Salivary Cortisol Concentrations
Status: COMPLETED
Conditions: Neck Pain
Interventions: PROCEDURE: cervical manipulation|PROCEDURE: cervical control exercises|PROCEDURE: Oscillatory mobilization technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Morphine With Nalbuphine in a Multimodal Approach for Pain Relief in Patients Undergoing Gynecological Procedures: Randomized Controlled Double Blind Clinical Trial
Status: COMPLETED
Conditions: Pain, Acute
Interventions: PROCEDURE: Morphine,
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cap Assisted Upper Endoscopy Versus High Definition White Light Endoscopy and Narrow Band Imaging Alone In The Detection Of Visible Lesions Barrett's Esophagus: A Randomized Tandem Study
Status: TERMINATED
Conditions: Barrett Esophagus
Interventions: PROCEDURE: Esophagogastroduodenoscopy with high definition-white light end endoscopy (HD-WLE) and narrow band imaging (NBI)|DEVICE: Olympus Disposable Distal Attachment Cap
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Posterior Tibial Nerve Stimulation for Children With Pelvic Floor Dyssynergia
Status: RECRUITING
Conditions: Constipation|Fecal Incontinence in Children|Pelvic Floor Dyssynergia
Interventions: DEVICE: Posterior Tibial Nerve Stimulation (PTNS)|DEVICE: Sham Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT