pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Can Dapagliflozin Preserve Structure and Function in Transplanted Kidneys?
Status: RECRUITING
Conditions: Kidney Transplant; Complications|Kidney Transplant Failure|Renal Failure
Interventions: DRUG: Dapagliflozin 10mg Tab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Participatory Design of Patient-centered Depression and Diabetes Care
Status: COMPLETED
Conditions: Depression|Type 2 Diabetes Mellitus
Interventions: BEHAVIORAL: Education, encouragement, card sort|BEHAVIORAL: Education, encouragement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Does Acupuncture Activate Endogenous Pain Inhibition in Chronic Whiplash?
Status: COMPLETED
Conditions: Whiplash
Interventions: OTHER: acupuncture|BEHAVIORAL: relaxation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Predictive Value of microRNA in Thyroid Cytologies of Undetermined Type
Status: RECRUITING
Conditions: Thyroid Cancer
Interventions: DIAGNOSTIC_TEST: Signature of microRNA for patients with bethesda classification 3, 4 or 5
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Long-Term Immune Persistence of GlaxoSmithKline Biologicals' Inactivated Hepatitis A Vaccine Injected According to a 0, 12-month Schedule
Status: COMPLETED
Conditions: Hepatitis A
Interventions: BIOLOGICAL: Havrix™
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Low-Dose Short-Term Ketorolac to Reduce Chronic Opioid Use in Orthopaedic Polytrauma Patients
Status: NOT_YET_RECRUITING
Conditions: Orthopaedic Polytrauma|Chronic Opioid Use
Interventions: DRUG: Ketorolac Injection|OTHER: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of a Virtually Implemented Cardiac Rehabilitation Program
Status: ACTIVE_NOT_RECRUITING
Conditions: Heart Failure
Interventions: OTHER: Virtually administered Cardiac Rehab program|OTHER: Standard of Care in person Cardiac Rehab Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Staccato Loxapine in Migraine (in Clinic)
Status: COMPLETED
Conditions: Migraine
Interventions: DRUG: Staccato Loxapine|DRUG: Staccato Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vitamin A Absorption From Cassava in Women
Status: COMPLETED
Conditions: Vitamin A Deficiency
Interventions: OTHER: Beta-Carotene bio-fortified cassava porridge without oil|OTHER: Beta-Carotene bio-fortified cassava porridge with oil|OTHER: White cassava porridge with retinyl palmitate reference dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Sarcosine (N-Methylglycine) Monotherapy for Schizophrenia
Status: COMPLETED
Conditions: Schizophrenias|Psychoses|Psychotic Disorders|Schizophrenic Disorders
Interventions: DRUG: Sarcosine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Drug-eluting Bead Transarterial Chemoembolisation (DEB-TACE) Versus (VS) Conventional Transarterial Chemoembolisation (cTACE) for Unresectable Hepatocellualr Carcinoma (HCC)
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma
Interventions: PROCEDURE: DEB-TACE|PROCEDURE: cTACE
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination of Vorinostat and Bortezomib in Relapsed or Refractory T-Cell Non-Hodgkin's Lymphoma
Status: TERMINATED
Conditions: Lymphoma
Interventions: DRUG: Vorinostat|DRUG: Bortezomib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the ENDOCUFF VISION® Endoscopy Cap Coupled With GI GENIUS™ Artificial Intelligence Compared to Each Device Alone in Improving Colonic Adenoma Detection Rate During Colonoscopy
Status: RECRUITING
Conditions: Colorectal Cancer|Adenoma|Intestinal Polyps
Interventions: PROCEDURE: GI GENIUS™ artificial intelligence system|PROCEDURE: ENDOCUFF VISION® endoscopic cap
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy and Safety of Octreotide in Laparoscopic Hepatectomy Surgery: Effect on Blood Loss, Need for Vasoactive Drugs, Transfusion Requirements.
Status: RECRUITING
Conditions: Hepatic Carcinoma|Hepatic Metastasis
Interventions: DRUG: Octreotide|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: An Open Internet-based Survey and Natural Language Processing Project Analysing Written Monologues by Headache Patients
Status: COMPLETED
Conditions: Headache Disorders|Tension-Type Headache|Migraine Disorders|Cluster Headache|TACS|Secondary Headache Disorder
Interventions: OTHER: Questionnaires
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Combination of Bortezomib, Fludarabine and Cyclophosphamide Treat Recurrent Mantle Cell Lymphoma
Status: UNKNOWN
Conditions: Mantle Cell Lymphoma Recurrent
Interventions: DRUG: Combination of Bortezomib, Fludarabine and Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessing the Technique of Ovarian Tissue Cryopreservation by Vitrification in Vietnam
Status: UNKNOWN
Conditions: Ovarian Tissue Cryopreservation|Vitrification
Interventions: OTHER: evaluation of the effectiveness of vitrification technique on ovarian tissue quality
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Long Term Postoperative Cognitive Dysfunction in the Elderly Patients
Status: UNKNOWN
Conditions: Cognitive Impairment
Interventions: BEHAVIORAL: Korean version of telephone interview for cognitive status|DRUG: Sevoflurane|DRUG: propofol|DEVICE: dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Integrative Medicine for Chemotherapy-Induced Peripheral Neuropathy
Status: COMPLETED
Conditions: Chemotherapy-induced Peripheral Neuropathy
Interventions: OTHER: Acupuncture|OTHER: Multi-modality (Acupuncture "plus")
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Outcomes and Events of Interest in Pregnant Women, Neonates and Infants and of RSV Surveillance
Status: COMPLETED
Conditions: Respiratory Syncytial Virus Infections
Interventions: PROCEDURE: Blood sample collection|PROCEDURE: Cord blood sample collection|OTHER: Maternal Diary Card|PROCEDURE: Nasal Swab collection|OTHER: Infant Diary Card
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Accuracy of a Newly Developed Mobile Application Versus the Conventional Method of Cephalometric Analysis in the Diagnosis of Dental and Skeletal Deformities Among Pre-adolescent Patients
Status: UNKNOWN
Conditions: Mobile Application|Cephalometric Analysis
Interventions: DIAGNOSTIC_TEST: newly developed mobile application
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety & Efficacy of Daptomycin Versus Standard of Care (SOC) in 1 - 17 Year Olds With Staphylococcus Aureus Bacteremia (MK-3009-005)
Status: COMPLETED
Conditions: Bacteremia
Interventions: DRUG: Daptomycin|DRUG: Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Plant-based Approaches to Stop Obesity Diet for the Treatment of Overweight and Obesity
Status: UNKNOWN
Conditions: Overweight and Obesity
Interventions: OTHER: PASO diet group|OTHER: Low-fat diet group|OTHER: Waiting list group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Internal Fit Evaluation of Indirect Restorations Using Cone Beam CT (CBCT)
Status: TERMINATED
Conditions: Indirect Restoration of Badly Broken Vital Teeth
Interventions: OTHER: restoration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: IVIG in the Treatment of Metastatic Cancers of the Prostate, Colon and Melanoma
Status: UNKNOWN
Conditions: Cancer of Colon|Malignant Melanoma|Urologic Cancer
Interventions: DRUG: IVIG|PROCEDURE: Biological Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sublingual Glycine vs. Placebo on Attentional Difficulties and Hyperactivity in Prepuberal Children
Status: COMPLETED
Conditions: Motor Activity|Attention Deficit|Stress, Psychological
Interventions: OTHER: microencapsulated Glycine|OTHER: Placebo tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: IMPACT-AML: Randomized Pragmatic Clinical Trial for Relapsed or Refractory AML
Status: RECRUITING
Conditions: Refractory Acute Myeloid Leukemia|Early Relapses of Acute Myeloid Leukemia
Interventions: OTHER: Intensive therapy|OTHER: Low intensity therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Smoking-cessation: A Spanish-Language Clinical Trial
Status: COMPLETED
Conditions: Smoking Cessation|Tobacco Dependence
Interventions: BEHAVIORAL: Stop Smoking for Good Intervention in Spanish (SS-SP)|BEHAVIORAL: Usual care (UC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Comparative Single-Dose Pharmacokinetic (PK) and Safety Study of Azilsartan Medoxomil in Children With Hypertension and in Healthy Adults
Status: TERMINATED
Conditions: Hypertension
Interventions: DRUG: Azilsartan medoxomil (TAK-491)|DRUG: Azilsartan medoxomil (TAK-491)|DRUG: Azilsartan medoxomil (TAK-491)|DRUG: Azilsartan medoxomil (TAK-491)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Effect of Teletherapy-supported Training on Nursing Students
Status: RECRUITING
Conditions: Low Back Pain|Neck Pain
Interventions: OTHER: teletherapy-guided exercise programme|OTHER: Waiting list/control intervention/delayed teletherapy intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Tension-type Headache With Articulatory and Suboccipital Soft Tissue Therapy
Status: COMPLETED
Conditions: Tension-type Headache
Interventions: OTHER: Manual Therapy|OTHER: Manual Therapy|OTHER: Manual Therapy|OTHER: Placebo control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Respicardia, Inc. Pivotal Trial of the remedē System
Status: COMPLETED
Conditions: Sleep Apnea, Central|Sleep Disordered Breathing|Heart Failure
Interventions: DEVICE: Treatment Group (transvenous stimulation of the phrenic nerve)|DEVICE: Control Group (Optimal Medical Therapy)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial of Folate With B12 in Patients With Schizophrenia With Residual Symptoms in Ethiopia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: folate with B12|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Passive Immunity Trial for Our Nation to Treat COVID-19 in Hospitalized Adults
Status: COMPLETED
Conditions: COVID-19|Coronavirus|SARS-CoV-2
Interventions: BIOLOGICAL: pathogen reduced SARS-CoV-2 convalescent plasma|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Universal Preventive Resilience Intervention to Improve and Promote Mental Health for Teenagers
Status: UNKNOWN
Conditions: Anxiety Symptoms|Depressive Symptoms|Behavioral Problem of Child|Mental Disorder in Adolescence|School Absenteeism|Bullying of Child|Cyberbullying|Violence in Adolescence
Interventions: BEHAVIORAL: UPRIGHT intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Randomized Multicenter Phase II/III Study With Adjuvant Gemcitabine Versus Neoadjuvant / Adjuvant FOLFIRINOX for Resectable Pancreas Carcinoma
Status: COMPLETED
Conditions: Resectable Prancreas Carcinoma
Interventions: DRUG: Gemcitabine|DRUG: Oxaliplatin|DRUG: 5-Fluorouracil|DRUG: Irinotecan|DRUG: Natriumfolinate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preoperative Coadministration of Low-concentration Carbohydrate and Nitrates Loading vs Low- Concentration Carbohydrate Loading Alone in Patients Undergoing Open Gynecological Surgeries
Status: RECRUITING
Conditions: Length of Hospital Stay
Interventions: DRUG: Low-concentration carbohydrate and nitrates|DRUG: Low-concentration carbohydrate|OTHER: Water with placebo capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: MSC for Treatment of cGVHD After Allo-HSCT
Status: UNKNOWN
Conditions: Chronic Graft-versus-host Disease
Interventions: BIOLOGICAL: Mesenchymal stem cells|DRUG: Glucocorticoids|DRUG: cyclosporine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intermittent Theta Burst Stimulation and Repetitive Transcranial Magnetic Stimulation Combined With Robotic Rehabilitation on Ambulation in Spinal Cord Injury Patients
Status: RECRUITING
Conditions: Spinal Cord Injuries
Interventions: DEVICE: Transcranial Magnetic Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Toripalimab in Combination With Nab-Paclitaxel For Patients With Metastatic or Recurrent Triple-Negative Breast Cancer (TNBC) With or Without Systemic Treatment
Status: ACTIVE_NOT_RECRUITING
Conditions: Triple-Negative Breast Cancer
Interventions: DRUG: JS001|DRUG: Nab-Paclitaxel|DRUG: Placebo|DRUG: Nab-Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multicenter Study of Safety and Efficacy Nivolumab at the Fixed Dose 40 mg (Nivo40) in Combination With Chemo-Immunotherapy for the Treatment of Newly Diagnosed PMBL
Status: RECRUITING
Conditions: Primary Mediastinal Lymphoma
Interventions: DRUG: Cyclophosphamide|DRUG: Doxorubicin Hydrochloride|DRUG: Etoposide Phosphate|DRUG: Prednisolone|DRUG: Rituximab|DRUG: Vincristine Sulfate|DRUG: Filgrastim|DRUG: Pegfilgrastim|DRUG: Nivolumab 40 mg in 4 ml Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Comparison of Bulk-fill Restorative and Nano-fill Resin Composite
Status: ACTIVE_NOT_RECRUITING
Conditions: Dental Caries
Interventions: DEVICE: Bulk-fill|DEVICE: Nano-fill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bi-trimalleolar Fracture and APOS System Treatment
Status: UNKNOWN
Conditions: Bi-trimalleolar Fracture of Ankle
Interventions: DEVICE: APOS SYSTEM|OTHER: APOS SYSTEM without biomechanics units.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Pilates on Functional Capacity and Blood Glucose Levels in Adults With Diabetes Type 2
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: OTHER: pilates exercise|OTHER: brisk walk
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial Evaluating the Efficacy and Safety of HSK21542 in PONV
Status: COMPLETED
Conditions: Postoperative Nausea and Vomiting
Interventions: DRUG: HSK21542-60μg|DRUG: HSK21542-120μg|DRUG: HSK21542-180μg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of the Impact of a Social Robot on Unwanted Loneliness in Elderly People Living in Nursing Homes
Status: NOT_YET_RECRUITING
Conditions: Elderly People|Nursing Home Residents|Loneliness|Quality of Life|Wellbeing|Social Interaction
Interventions: OTHER: Cognitive|OTHER: Mobility|OTHER: Social|OTHER: Relational|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Clinical Study of Orelabrutinib Combined With BG Regimen First-line Treatment of CLL/SLL
Status: NOT_YET_RECRUITING
Conditions: CLL/SLL
Interventions: DRUG: Orelabrutinib and BG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Pennsaid on Clinical Neuropathic Pain
Status: COMPLETED
Conditions: Neuralgia|Postherpetic Neuralgia|Reflex Sympathetic Dystrophy|Complex Regional Pain Syndrome (CRPS)
Interventions: DRUG: Pennsaid|DRUG: Placebo (2.3% DMSO solution)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Rituximab, Bendamustine and Cytarabine Followed by Venetoclax in High Risk Elderly Patients With MCL
Status: ACTIVE_NOT_RECRUITING
Conditions: Lymphoma, Mantle-Cell
Interventions: DRUG: Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Repurposing Clinically Approved Drugs for Yaws With an Insight Into the Cutaneous Ulcer Disease Syndrome (Trep-AByaws)
Status: ACTIVE_NOT_RECRUITING
Conditions: Yaws|Cutaneous Ulcer
Interventions: DRUG: Linezolid Oral Tablet|DRUG: Azithromycin Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: HD-tDCS: Effects on the Somatosensory System
Status: COMPLETED
Conditions: Acute Pain|Neuroplasticity|Brain Modulation|Somatosensory Function
Interventions: DEVICE: Primary Motor Cortex Stimulation|DEVICE: Dorsolateral Prefrontal Cortex Stimulation|DEVICE: Multimodal Stimulation (DLPFC+M1)|DEVICE: Sham stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Phase 2 Study of 9-ING-41Combined With Chemotherapy in Adolescents and Adults With Advanced Sarcomas
Status: WITHDRAWN
Conditions: Sarcoma|Soft Tissue Sarcoma|Metastatic Sarcoma|Undifferentiated Pleomorphic Sarcoma|Myxofibrosarcoma|Leiomyosarcoma|Liposarcoma|Angiosarcoma|Synovial Sarcoma|Rhabdomyosarcoma|Spindle Cell Sarcoma|High Grade Sarcoma|Bone Sarcoma
Interventions: DRUG: Gemcitabine|DRUG: Docetaxel|DRUG: 9-ING-41
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Prospective, Open Label, Dose-escalation, SAD/MAD, Multicenter, 24weeks, Phase I/IIa Clinical Trial to Evaluate the Safety, Tolerability and Pharmacodynamics of Investigational Product (VM-001) in Patients With Graft-versus-host Disease(GvHD)
Status: NOT_YET_RECRUITING
Conditions: Graft Versus Host Disease
Interventions: BIOLOGICAL: VM-001 1X10^6 cells/kg|BIOLOGICAL: VM-001 3X10^6 cells/kg|BIOLOGICAL: VM-001 5X10^6 cells/kg|BIOLOGICAL: VM-001 1X10^6 cells/kg two dose|BIOLOGICAL: VM-001 1X10^6 cells/kg four dose
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Auditory Training and Hearing Aid Satisfaction
Status: COMPLETED
Conditions: Hearing Impairment, Sensorineural
Interventions: BEHAVIORAL: Auditory Brian Training Games/Activities
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Comparing Effects of Diet, With or Without Exercise, on Sexual, Urinary and Endothelial Function, Inflammatory Profile and Quality of Life in Obese Men
Status: COMPLETED
Conditions: Sexual Dysfunction|Endothelial Dysfunction|Quality of Life|Inflammation
Interventions: BEHAVIORAL: weight loss counselling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics and Pharmacodynamics of BI 1356 in Subjects With Different Degrees of Liver Impairment as Compared to Healthy Subjects
Status: COMPLETED
Conditions: Hepatic Insufficiency
Interventions: DRUG: BI 1356
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The HIV Functional Cure Potential of UB-421 in ART Stabilized HIV-1 Patients
Status: COMPLETED
Conditions: HIV-1 Infection
Interventions: BIOLOGICAL: UB-421(25 mg/kg) Q2W|BIOLOGICAL: UB-421(25 mg/kg) Q4W
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Spinal Cord Stimulation (SCS) on Insulin Secretion in Humans
Status: WITHDRAWN
Conditions: Spinal Cord Stimulation|Insulin Secretion
Interventions: DEVICE: BurstDR stimulation|DEVICE: Tonic stimulation|DEVICE: No stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Initiating Mealtime Ultra-Rapid Acting Insulin (Afrezza) in Uncontrolled Type 2 Diabetes Patients
Status: COMPLETED
Conditions: Type2 Diabetes
Interventions: DRUG: Afrezza Inhalant Product
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Treatment of Ocular Adnexal Extranodal Marginal Zone B-cell Lymphoma by Orelabrutinib and Radiotherapy
Status: RECRUITING
Conditions: Extranodal Marginal Zone B-cell Lymphoma
Interventions: DRUG: Orelabrutinib|RADIATION: Ultra-low dose radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I / II Vorinostat, Erlotinib and Temozolomide for Recurrent Glioblastoma Multiforme (GBM)
Status: TERMINATED
Conditions: Brain Cancer|Glioblastoma Multiforme
Interventions: DRUG: Vorinostat|DRUG: Erlotinib|DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Double-task Exercise in Older Adults at Risk of Cognitive Decline (MeMo-Health-Cog-3 Program)
Status: ACTIVE_NOT_RECRUITING
Conditions: Cognitive Decline|Vascular Health
Interventions: OTHER: Control excercise|OTHER: "Mind and Movement for Cognitive Health in the Older Adult"|OTHER: Double-task exercise by older adults and their caregivers
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Thorough QT Study of ABBV-CLS-7262 in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: ABBV-CLS-7262|DRUG: ABBV-CLS-7262|DRUG: Placebo|DRUG: Moxifloxacin 400mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Maximal Dose of Angiotensin Converting Enzyme (ACE) Inhibitor for Treatment of Diabetic Kidney Disease
Status: COMPLETED
Conditions: Diabetes Mellitus, Type I|Diabetic Nephropathy
Interventions: DRUG: Lisinopril
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Indocyanine Green Versus Blue Dye for Detection of Sentinel Lymph Node In Endometrial Cancer
Status: COMPLETED
Conditions: Endometrial Neoplasms
Interventions: PROCEDURE: Sentinel lymph node biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: KULEA-NET: A Mobile Application for African American/Black Mothers to Promote Exclusive and Continuous Breastfeeding
Status: ENROLLING_BY_INVITATION
Conditions: Breastfeeding|Exclusive Breastfeeding
Interventions: BEHAVIORAL: KULEA-NET application|BEHAVIORAL: Control Group: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: HD-tDCS for Hallucinations
Status: NOT_YET_RECRUITING
Conditions: Schizophrenia|Hallucinations
Interventions: PROCEDURE: High-definition transcranial direct current (HD-tDCS), active condition|PROCEDURE: High-definition transcranial direct current (HD-tDCS), sham condition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Tapering Immunosuppressants on Maintaining Minimal Disease Activity in Adult Subjects With Psoriatic Arthritis
Status: RECRUITING
Conditions: Psoriatic Arthritis|Withdrawal|Reduction
Interventions: DRUG: Prednisolone|DRUG: Sulfasalazine|DRUG: Leflunomide|DRUG: Methotrexate|DRUG: Tofacitinib|DRUG: Apremilast|DRUG: Etanercept|DRUG: Adalimumab|DRUG: Infliximab|DRUG: Certolizumab pegol|DRUG: Golimumab|DRUG: Abatacept|DRUG: Secukinumab|DRUG: Ixekizumab|DRUG: Ustekinumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of the Second Generation Dutasteride and Tamsulosin HCl Combination Capsule in Fed State
Status: COMPLETED
Conditions: Urologic Diseases
Interventions: DRUG: Commercially available combination of dutasteride 0.5 mg and tamsulosin HCL 0.4 mg|DRUG: Second generation dutasteride 0.5 mg and tamsulosin HCL 0.4 mg combination capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Effect of Body Awareness Therapy on Postural Stability, Balance and Fear of Falling in Patients With COPD
Status: UNKNOWN
Conditions: Asthma
Interventions: OTHER: Body Awareness Therapy|OTHER: Pulmonary Rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of C134 in Patients With Recurrent GBM
Status: ACTIVE_NOT_RECRUITING
Conditions: Glioblastoma Multiforme of Brain|Anaplastic Astrocytoma of Brain|Gliosarcoma of Brain
Interventions: BIOLOGICAL: C134
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Outcomes and Major Adverse Events in Patients Treated With Physician-Modified Fenestrated and Branched Stent Grafts
Status: NOT_YET_RECRUITING
Conditions: Juxtarenal Aortic Aneurysm|Pararenal Aneurysm|Thoracoabdominal Aortic Aneurysm
Interventions: DEVICE: Cook Alpha TX2 Stent Graft, Cook Zenith TX2, and Cook Zenith Fenestrated Stent Graft
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chemo/XRT +/- Amifostine to Assess Outcomes Related to Xerostomia, Mucositis, & Dysphagia
Status: TERMINATED
Conditions: Dysphagia|Head and Neck Cancer|Mucositis|Xerostomia
Interventions: BEHAVIORAL: exercise intervention|DRUG: amifostine trihydrate|PROCEDURE: therapeutic dietary intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effects of Regular Home Use Vs Diabetic Team- Supported Use of the Medtronic CareLink Therapy Management System.
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: OTHER: Medtronic CareLink therapy management system|OTHER: regular home use and Medtronic CareLink Therapy Management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Cholecalciferol in Treating Patients With Myelodysplastic Syndrome
Status: COMPLETED
Conditions: Leukemia|Myelodysplastic Syndromes|Myelodysplastic/Myeloproliferative Neoplasms
Interventions: DIETARY_SUPPLEMENT: cholecalciferol
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Conservative Treatment of Gastrointestinal Fistulas by Endoscopic Injection of tSVFem
Status: UNKNOWN
Conditions: Gastrointestinal Fistula
Interventions: PROCEDURE: injection of emulsified adipose tissue stromal vascular fraction
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Biomechanics and Intrinsic Foot Muscle Roles in Subjects With Chronic Ankle Instability
Status: RECRUITING
Conditions: Chronic Ankle Instability|Lateral Ankle Sprain
Interventions: BEHAVIORAL: Intrinsic foot muscle fatigue
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Freeze-Dried Black Raspberries in Treating Patients With Oral Squamous Cell Cancer Undergoing Surgery
Status: COMPLETED
Conditions: Squamous Cell Carcinoma of Mouth
Interventions: OTHER: laboratory biomarker analysis|OTHER: preventative dietary intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Wall Shear Stress and Neointimal Healing Following PCI in Angulated Coronary Vessels
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DEVICE: Resolute Integrity Zotarolimus eluting stent|DEVICE: Xience Xpedition everolimus eluting stent|DEVICE: Optical Coherence Tomography (OCT)|DEVICE: Intravascular Ultrasound (IVUS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Brain-behavior Associations of Sensorimotor Therapy Post Stroke
Status: COMPLETED
Conditions: Stroke
Interventions: OTHER: additional sensorimotor therapy for the upper limb|OTHER: additional motor therapy for the upper limb after stroke
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Postoperative Enteral Immunonutrition in Gastric Cancer
Status: COMPLETED
Conditions: Gastric Cancer
Interventions: DIETARY_SUPPLEMENT: Immunomodulating nutrition (Reconvan)|DIETARY_SUPPLEMENT: Standard nutrition (Peptisorb)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Brain Response to Serotonergic Medications in ASD
Status: UNKNOWN
Conditions: Autism Spectrum Disorder
Interventions: DRUG: Placebo|DRUG: Citalopram|DRUG: Tianeptine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Amnion-Chorion Allograft Barrier Used for Root Surface and Guided Tissue Regeneration
Status: COMPLETED
Conditions: Periodontal Diseases
Interventions: PROCEDURE: Amnion-Chorion allograft membrane on the root surface of periodontally diseased site.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Recording "Fast Ripples" Using Microelectrodes During Stereo-encephalography in Patients With Drug-resistant Partial Epilepsy
Status: COMPLETED
Conditions: Epilepsy
Interventions: DEVICE: intracerebral micro-macroelectrodes
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of CPI-0209 in Patients With Advanced Solid Tumors and Lymphomas
Status: RECRUITING
Conditions: Advanced Solid Tumor|Diffuse Large B Cell Lymphoma|Lymphoma, T-Cell|Mesothelioma, Malignant|Prostatic Neoplasms, Castration-Resistant|Endometrial Cancer|Ovarian Clear Cell Carcinoma
Interventions: DRUG: CPI-0209
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Manual Therapy and Strengthening Exercises in Hemophilic Arthropathy of the Elbow Joint
Status: COMPLETED
Conditions: Hemophilia|Arthritis
Interventions: OTHER: Manual therapy|OTHER: Strengthening exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nivolumab With or Without Ipilimumab in Treating Patients With Resectable Liver Cancer
Status: COMPLETED
Conditions: Hepatocellular Carcinoma|Resectable Hepatocellular Carcinoma
Interventions: BIOLOGICAL: Ipilimumab|BIOLOGICAL: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Integrative Neuromuscular Training in Adolescents and Children Treated for Cancer
Status: RECRUITING
Conditions: Pediatric Cancer|Leukemia|Neoplasms|Lymphoma|Solid Tumor|CNS Tumor
Interventions: BEHAVIORAL: Integrative neuromuscular training (INT)|BEHAVIORAL: Active control group: home-based training program|BEHAVIORAL: motivational counseling session
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Adjuvant Befotertinib in Stage IB-IIIB Non-small Cell Lung Cancer With Positive EGFR Sensitive Mutations
Status: RECRUITING
Conditions: Non-Small Cell Lung Cancer|EGFR Sensitive Mutation|Adjuvant Therapy
Interventions: DRUG: Befotertinib + Icotinib placebo|DRUG: Icotinib + Befotertinib placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Seated Exercises and Psychoeducational Rehabilitation on Fatigue and Coping of Women Postmastectomy
Status: COMPLETED
Conditions: Fatigue|Coping Behavior
Interventions: BEHAVIORAL: Seated Exercises|BEHAVIORAL: Psychoeducational Rehabilitation|BEHAVIORAL: Routine Care
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Enstilar in Combination With Enbrel or Humira for Plaque Psoriasis
Status: RECRUITING
Conditions: Psoriasis
Interventions: DRUG: Enstilar 0.005%-0.064% Topical Foam
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety, Tolerability, and Fecal Pharmacokinetics of BX002-A in Healthy Adults
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: BIOLOGICAL: BX002-A|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: A Study to Investigate the Effect of CYP3A Inhibition on the Pharmacokinetics of RO7017773 in Healthy Participants
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: RO7017773|DRUG: Itraconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acute Episodes in Chronic Stable Angina: Assessment of the Use of the Coronary Vasodilator Propatyl Nitrate.
Status: COMPLETED
Conditions: Chronic Stable Angina Pectoris
Interventions: DRUG: Propatyl Nitrate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety,Tolerability,Pharmacokinetics and Efficacy of CFZ533 in Moderate to Severe Myasthenia Gravis
Status: COMPLETED
Conditions: Myasthenia Gravis, Generalized
Interventions: DRUG: Placebo|DRUG: CFZ533
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Out-of-home Consumer Food Purchase Behaviour in the Presence and Absence of Value Pricing and Price Promotions
Status: NOT_YET_RECRUITING
Conditions: Food Selection|Healthy Eating|Eating Behavior
Interventions: BEHAVIORAL: Control|BEHAVIORAL: Product price promotions removed|BEHAVIORAL: Bulk buy reductions removed|BEHAVIORAL: Volume value pricing removed|BEHAVIORAL: No price-based incentives
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Maintenance Bee-Venom Immunotherapy Administered at 6-Month Intervals Does Not Protect Against re-Stings
Status: COMPLETED
Conditions: Venom Allergy
Interventions: DRUG: venom immunotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radiation, Cetuximab and Pemetrexed With or Without Bevacizumab in Locally Advanced Head and Neck Cancer
Status: COMPLETED
Conditions: Cancer
Interventions: DRUG: Bevacizumab|DRUG: Cetuximab|DRUG: Pemetrexed|RADIATION: Radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Influence of Thoracic Paravertebral Block on Cardiac Repolarization
Status: COMPLETED
Conditions: Paravertebral Block|QT Interval
Interventions: PROCEDURE: Paravertebral block (ropivacaine) left|PROCEDURE: Paravertebral block (ropivacaine) right
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Intrauterine Insemination In HIV-Discordant Couples
Status: TERMINATED
Conditions: HIV-1|Fertility|Infertility
Interventions: OTHER: Sperm Washing with Intrauterine Insemination (IUI)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exploring the Complex Links Between Menstrual Irregularity and Cellular Markers
Status: COMPLETED
Conditions: Menstrual Irregularity|Menstrual Cycle Abnormal
Interventions: DIAGNOSTIC_TEST: Serum ADMA, MDA and M30 levels mesurment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study to Evaluate Mezigdomide in Combination With Carfilzomib and Dexamethasone (MeziKD) Versus Carfilzomib and Dexamethasone (Kd) in Participants With Relapsed or Refractory Multiple Myeloma (SUCCESSOR-2)
Status: RECRUITING
Conditions: Relapsed or Refractory Multiple Myeloma
Interventions: DRUG: Mezigdomide|DRUG: Carfilzomib|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of an Intensive Education Program on the Treatment of Tobacco Use Disorder for Pharmacists: a Randomized Controlled Trial
Status: COMPLETED
Conditions: Smoking Cessation
Interventions: BEHAVIORAL: intensive multi-disciplinary education program on tobacco treatment for pharmacists|OTHER: Control arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Do Patients With Skin Psoriasis Have Sub-clinical Features of Active Psoriatic Arthritis on Musculoskeletal UltraSound?
Status: ACTIVE_NOT_RECRUITING
Conditions: Psoriatic Arthritis
Interventions: DIAGNOSTIC_TEST: Ultrasound scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: 18F-Sodium Fluoride (18F-NaF) PET-CT Imaging to Identify Vulnerable Plaques in Patients With Diabetes
Status: COMPLETED
Conditions: Atherosclerosis|Complications of Diabetes Mellitus
Interventions: RADIATION: 18Fluoride-Sodium Fluoride radio-isotope
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Trial of SHR-1210 (an Anti-PD-1 Inhibitor) in Combination With Apatinib in Patients With Advanced HCC(RESCUE)
Status: COMPLETED
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: SHR 1210+apatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Autologous Cord Blood Cells for Prevention of BPD in Preterm
Status: COMPLETED
Conditions: Safety Issues|BPD - Bronchopulmonary Dysplasia|Neonatal Death
Interventions: OTHER: Autologous Umbilical Cord Blood Mononuclear Cells infusion Therapy|DRUG: 0.9% Sodiun Chloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Bioequivalence Study of Levocetirizine DiHCl Tablets 5mg of Dr. Reddy's Under Fasting Conditions
Status: COMPLETED
Conditions: Fasting
Interventions: DRUG: Levocetirizine DiHCl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: DNX-2401 (Formerly Known as Delta-24-RGD-4C) for Recurrent Malignant Gliomas
Status: COMPLETED
Conditions: Brain Cancer|Central Nervous System Diseases
Interventions: DRUG: DNX-2401|PROCEDURE: Tumor Removal
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Experimental Peri-implant Mucositis on Implant Sites That Were Previously Treated With or Without Implantoplasty
Status: ENROLLING_BY_INVITATION
Conditions: Peri-implant Mucositis|Peri-Implantitis
Interventions: PROCEDURE: Induction of experimental peri-implant mucositis|PROCEDURE: Resolution of experimental peri-implant mucositis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study on the Mode and Mechanism of Ultra-low Frequency rTMS for Sleep Disorders in Patients With Parkinson's Disease
Status: UNKNOWN
Conditions: Repetitive Transcranial Magnetic Stimulation|Parkinson Disease|Sleep Disorder
Interventions: DEVICE: Ultra-low frequency repetitive transcranial magnetic stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: HSV-2 Suppression to Reduce HIV-1 Levels in HIV-1, HSV-2 Co-infected Men.
Status: COMPLETED
Conditions: HIV Infection|Herpes Simplex|Sexually Transmitted Diseases
Interventions: DRUG: valacyclovir|DRUG: matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Randomized Placebo Controlled Trial of the Effectiveness of Metformin in Addition to Usual Care in the Reduction of Gestational Diabetes Mellitus Effects
Status: COMPLETED
Conditions: Gestational Diabetes
Interventions: DRUG: Metformin Hydrochloride|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Postpartum Massage Therapy for Women and Infants: The Effect on Maternal Depression, Stress, Fatigue and Infant Temperament
Status: COMPLETED
Conditions: Postpartum Depression
Interventions: OTHER: Massage therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I/II, Study of Selective Inhibitor of Nuclear Export (SINE) Selinexor (KPT-330) + Sorafenib in Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Leukemia|Acute Myeloid Leukemia
Interventions: DRUG: Selinexor|DRUG: Sorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radiofrequency Ablation for Biliopancreatic Malignancy
Status: COMPLETED
Conditions: Pancreas Cancer|Cholangiocarcinoma|Obstructive Jaundice
Interventions: DEVICE: Radiofrequency ablation (StarMed)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT