pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Research Trial of Aralast NP in New Onset Diabetes (RETAIN) - Part II
Status: WITHDRAWN
Conditions: Diabetes Mellitus, Type 1
Interventions: DRUG: Aralast NP|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PET in Breast Cancer Receiving Neoadjuvant Chemotherapy
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: docetaxel (75 mg/m2) and doxorubicin (50 mg/m2)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Study to Assess Efficacy & Safety of WP1302 Prevent Relapse of MMI w/Draw in Subj. w/ Graves' dz
Status: SUSPENDED
Conditions: Graves Disease
Interventions: DRUG: WP1302|DRUG: WP1302 placebo|COMBINATION_PRODUCT: methimazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Family History Study of Alcohol Consumption Using Memantine
Status: COMPLETED
Conditions: Alcohol Drinking
Interventions: DRUG: memantine|DRUG: Memantine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Extracorporeal Photopheresis for Acute Graft Versus Host Disease
Status: UNKNOWN
Conditions: Graft Versus Host Disease|Cancer|Stem Cell Transplantation
Interventions: PROCEDURE: Extracorporeal Photopheresis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Open-Labeled, Extended-Use of XERECEPT (hCRF) for Patients in Studies NTI 0302, 0303, or Other Designated Studies
Status: COMPLETED
Conditions: Brain Edema|Brain Tumor
Interventions: DRUG: hCRF [XERECEPT (corticorelin acetate injection)]
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Erlotinib Hydrochloride With or Without Celecoxib in Treating Patients With Stage IIIB-IV Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Recurrent Non-small Cell Lung Cancer|Stage IIIB Non-small Cell Lung Cancer|Stage IV Non-small Cell Lung Cancer
Interventions: DRUG: erlotinib hydrochloride|DRUG: celecoxib|OTHER: placebo|OTHER: laboratory biomarker analysis|OTHER: immunohistochemistry staining method|GENETIC: fluorescence in situ hybridization|GENETIC: mutation analysis|GENETIC: protein expression analysis|GENETIC: gene expression analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pucotenlimab Combined With Lenvatinib as a Neodjuvant Therapy for Non Clear Cell Renal Cell Carcinoma
Status: NOT_YET_RECRUITING
Conditions: Renal Cell Carcinoma
Interventions: DRUG: Pucotenlimab Combined With Lenvatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Does the Hyoscine N-Butylbromide Administered During Colonoscopy Increase the Adenoma Detection Rate?
Status: UNKNOWN
Conditions: Colonic Adenomas
Interventions: DRUG: Hyoscine Butyl Bromide 20mg/2 ml i.v.|DRUG: Saline 2 ml i.v.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: DIAGNOSTIC
Clinical trial: Patient Outcomes Collection: How Can we do Better?
Status: RECRUITING
Conditions: Shoulder Pain
Interventions: BEHAVIORAL: Email reminders|BEHAVIORAL: Pre- and Post-operative discussion|BEHAVIORAL: Incentive
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Staccato Loxapine in Agitated Patients With Bipolar Disorder
Status: COMPLETED
Conditions: Bipolar I Disorder
Interventions: DRUG: Inhaled Placebo|DRUG: Inhaled loxapine 5 mg|DRUG: Inhaled loxapine 10 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Herbmed Plus in Ureteral Stent Discomfort
Status: COMPLETED
Conditions: Ureteral Stent Discomfort
Interventions: DRUG: Herbmed plus|DRUG: Placebo|DRUG: Tolterodine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Motor Imagery Technique on Lower Limb Function Among Stroke Patients.
Status: COMPLETED
Conditions: Spasticity as Sequela of Stroke|Gait, Hemiplegic|Quality of Life
Interventions: OTHER: Motor imagery technique|OTHER: Conventional Physical Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cerebellar Transcranial Direct Current Stimulation in Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson Disease|Brain Stimulation|Cerebellum
Interventions: DEVICE: Transcranial direct current stimulation at 2 mA|DEVICE: Transcranial direct current stimulation at 4 mA|DEVICE: Sham transcranial direct current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Plasma Exchange for Severe Crescentic IgA Nephropathy
Status: TERMINATED
Conditions: Glomerulonephritis, IGA|Kidney Diseases|Acute Renal Insufficiency|Rapidly Progressive Glomerulonephritis
Interventions: PROCEDURE: Plasma Exchange (PE)|DRUG: Methylprednisolone pulse
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dermacyd PH_DETINLYN (Lactic Acid) Sweet Flower - Compatibility
Status: COMPLETED
Conditions: Hygiene
Interventions: DRUG: Dermacyd PH_DETINLYN (Lactic Acid)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: |Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Evaluate the Effects of Milnacipran on Pain Processing and Functional MRI in Patients With Fibromyalgia
Status: COMPLETED
Conditions: Fibromyalgia
Interventions: DRUG: milnacipran|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of Camrelizumab (SHR-1210) in Combination With Concurrent Chemoradiotherapy in Locally Advanced Esophageal Cancer
Status: UNKNOWN
Conditions: Esophageal Cancer
Interventions: DRUG: Camrelizumab|DRUG: Paclitaxel|DRUG: Cisplatin|DRUG: Placebo|RADIATION: Radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Two Anesthetic Drugs on Some Enzyme Levels in Patients Undergoing Lower Extremity Surgery
Status: COMPLETED
Conditions: Malondialdehyde|Heme Oxygenase|C-Reactive Protein
Interventions: OTHER: Saline|OTHER: Dexmedetomidine|OTHER: Ketamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Confirmatory Safety and Efficacy Study of BBI-4000 in Subjects With Axillary Hyperhidrosis
Status: COMPLETED
Conditions: Hyperhidrosis
Interventions: DRUG: BBI-4000 gel, 5%|DRUG: BBI-4000 gel, 10%|DRUG: BBI-4000 gel, 15%|DRUG: Vehicle (Placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: To Assess the Efficacy of GP681 Tablet Versus Placebo in Patients With Acute Uncomplicated Influenza Virus Infection
Status: COMPLETED
Conditions: Influenza
Interventions: DRUG: GP681 40mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Study of the IDO Inhibitor Epacadostat Versus Tamoxifen for Subjects With Biochemical-recurrent-only EOC, PPC or FTC Following Complete Remission With First-line Chemotherapy
Status: TERMINATED
Conditions: Ovarian Cancer|Genitourinary (GU) Tumors
Interventions: DRUG: Epacadostat|DRUG: tamoxifen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Analgesic Effect of Quadratus Lumborum Block Application After Laparoscopic Cholecystectomy Surgery
Status: COMPLETED
Conditions: Cholecystectomy|Postoperative Pain|Nerve Block
Interventions: DRUG: Tramadol|PROCEDURE: Ultrasound guided Quadratus Lumborum block|PROCEDURE: Ultrasound guided placebo Quadratus Lumborum block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Cabazitaxel/Prednisone Alone or in Combination With Custirsen for 2nd Line Chemotherapy in Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: cabazitaxel|DRUG: prednisone|DRUG: custirsen sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TicAgrelor Versus CLOpidogrel in Stabilized Patients With Acute Myocardial Infarction: TALOS-AMI
Status: COMPLETED
Conditions: Acute Myocardial Infarction
Interventions: DRUG: Aspirin+Ticagrelor|DRUG: Aspirin+Clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Telomerase Activator and Retinal Amyloid
Status: COMPLETED
Conditions: Alzheimer Disease
Interventions: DIETARY_SUPPLEMENT: cycloastragenol|DIETARY_SUPPLEMENT: placebo (for cycloastragenol)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Regulation of Brain Glucose Metabolism in Type 1 Diabetes
Status: NOT_YET_RECRUITING
Conditions: Diabetes Mellitus, Type 1|Hypoglycemia Unawareness
Interventions: DRUG: Dichloroacetate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: New Health Devices to Improve Adherence to Physical Activity in Overweight Inactive Adults
Status: COMPLETED
Conditions: Cardiovascular Diseases|Obesity
Interventions: DEVICE: Pai APP|DEVICE: FitBit APP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Herbal Treatment for Perennial Allergic Rhinitis
Status: COMPLETED
Conditions: Perennial Allergic Rhinitis
Interventions: DRUG: Shi-Bi-Lin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cediranib Maleate With or Without Gefitinib in Treating Patients With Recurrent or Progressive Glioblastoma
Status: TERMINATED
Conditions: Glioblastoma
Interventions: DRUG: cediranib maleate|DRUG: gefitinib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: BDD With UDCA Therapy After Laparoscopic Cholecystectomy
Status: UNKNOWN
Conditions: Cholecystitis, Acute|Cholecystitis, Chronic
Interventions: DRUG: BDD with UDCA|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Preload Dependency Via Measurement of Peripheral Venous Pressure During an Alveolar Recruitment Manoeuvre
Status: TERMINATED
Conditions: Intensive Care Patients
Interventions: PROCEDURE: alveolar recruitment manoeuvre by pressure step
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Project H-COVID: Evaluating Hyper-Brief, Online Materials During the COVID-19 Pandemic
Status: COMPLETED
Conditions: Anxiety
Interventions: BEHAVIORAL: Contain COVID Anxiety SSI|BEHAVIORAL: Remain COVID Free SSI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Evaluate the Pharmacokinetic Profiles and Safety of CKD-387 in Healthy Volunteers Under Fasting Conditions
Status: COMPLETED
Conditions: Endocrine, Nutritional and Metabolic Diseases
Interventions: DRUG: CKD-387|DRUG: D484
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Measuring Acute Drug Demand in Humans
Status: RECRUITING
Conditions: Opioid Use Disorder|Opioid Dependence
Interventions: DRUG: Drug A (Blinded Drug)|DRUG: Drug B (Blinded Drug)|DRUG: Drug C (Blinded Drug)|DRUG: Drug D (Blinded Drug)|DRUG: Suvorexant (20mg/day)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Docetaxel and Trastuzumab With or Without Carboplatin in Treating Women With HER2-Positive Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: BIOLOGICAL: trastuzumab|DRUG: carboplatin|DRUG: docetaxel|BIOLOGICAL: trastuxumab|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Erlotinib,Radiation and Cisplatin in Patients With Complete Resected Squamous Cell Carcinoma of the Head and Neck
Status: COMPLETED
Conditions: Squamous Cell Carcinoma of the Head and Neck
Interventions: DRUG: Erlotinib chlorhydrate|DRUG: Cisplatin|PROCEDURE: Radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Drug Eluting Balloon for Early Fistula Failure Trial
Status: UNKNOWN
Conditions: Stenosis of Arteriovenous Dialysis Fistula
Interventions: DRUG: Drug Eluting Balloon|PROCEDURE: Regular angioplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: High Flow Nasal Cannula Therapy for Early Management of Acute Hypercapnic Cardiogenic Pulmonary Edema in the Emergency Department
Status: COMPLETED
Conditions: Acute Cardiogenic Pulmonary Edema|Hypercapnic Respiratory Failure
Interventions: DEVICE: High flow nasal therapy (HFNT) : Optiflow™|DEVICE: Non invasive ventilation (niv)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Mirror Therapy vs Cross Education Non Paretic Limb Training on Strength and Hand Dexterity in Stroke Survivors.
Status: RECRUITING
Conditions: Hemiplegia and Hemiparesis
Interventions: OTHER: Cross education|OTHER: Mirror Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Multiple-ascending Doses of GSBR-1290 in Healthy Overweight/Obese Participants
Status: ACTIVE_NOT_RECRUITING
Conditions: Healthy Volunteers
Interventions: DRUG: GSBR-1290 (Capsule/Tablet)|DRUG: GSBR-1290|DRUG: Placebo|DRUG: Placebo (Capsule/Tablet)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: EXL01 in the Maintenance of Steroid-induced Clinical Response/Remission in Participants With Mild to Moderate Crohn's Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Crohn Disease
Interventions: DRUG: EXL01|DRUG: Placebo|OTHER: SoC corticosteroid - Induction Period|OTHER: SoC corticosteroid - Tapering
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Home-based Mirror Therapy Combined With Task-oriented Training for Patients With Stroke
Status: COMPLETED
Conditions: Stroke
Interventions: BEHAVIORAL: home-based MTOT|BEHAVIORAL: hospital-based therapy|BEHAVIORAL: hospital-based MTOT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Partner-Assisted Interpersonal Psychotherapy or Antidepressant Medication for Antenatal Depression
Status: TERMINATED
Conditions: Partner Assisted Interpersonal Psychotherapy|Treatment as Usual
Interventions: BEHAVIORAL: Partner-Assisted Interpersonal Psychotherapy|OTHER: Treatment as Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dried Leaf Artemisia (DLA) Compared to Artemisinin Combination Therapy (ACT) vs Malaria
Status: WITHDRAWN
Conditions: Malaria
Interventions: DRUG: ACT|DRUG: DLA1|DRUG: DLA2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Ramelteon in Elderly Subjects With Chronic Insomnia
Status: COMPLETED
Conditions: Chronic Insomnia
Interventions: DRUG: Ramelteon|DRUG: Ramelteon|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SIM0718 Treatment of Asthma Clinical Study
Status: NOT_YET_RECRUITING
Conditions: Asthma; Eosinophilic
Interventions: DRUG: SIM0718 injection|DRUG: SIM0718 injection of placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Benefits of Immediate Treatment Initiation Without Immunovirological Data Compared to Conventional BIC / FTC / TAF Treatment in Naive Patients With Type 1 HIV (Human Immunodeficiency Virus) Infection
Status: COMPLETED
Conditions: HIV-1-infection
Interventions: DRUG: BIC/FTC/TAF: Bictegravir/emtricitabina/tenofovir alafenamida fumarato
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Relationship Between Nitric Oxide (NO) in Follicular Fluid and Sperm Fertilization Ability
Status: UNKNOWN
Conditions: Male Infertility
Interventions: OTHER: Control (fertile semen donors)|OTHER: Patients (subfertile men)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Double-blind, Escalating Dose, Randomized, Placebo-controlled Study Assessing PK, Safety, Tolerability in Non-ambulant DMD Subjects
Status: COMPLETED
Conditions: Muscular Dystrophies
Interventions: DRUG: 3 mg/kg GSK2402968|DRUG: 6 mg/kg GSK2402968|DRUG: 9 mg/kg GSK2402968|DRUG: 12 mg/kg GSK2402968|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Double-Blind, Four Week Trial Of [S,S]-Reboxetine And Atomoxetine In Adults With Attention Deficit Hyperactivity Disorder.
Status: WITHDRAWN
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: DRUG: Atomoxetine|DRUG: PNU-165442G; [S,S]-reboxetine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Study of NGM621 in Participants With Geographic Atrophy
Status: COMPLETED
Conditions: Geographic Atrophy
Interventions: BIOLOGICAL: NGM621|BIOLOGICAL: NGM621|OTHER: Sham Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Follow up Trial for Keppra (Levetiracetam) as Monotherapy in Patients With Newly Diagnosed Epilepsy Coming From N01175 (NCT00175903).
Status: COMPLETED
Conditions: Epilepsy
Interventions: DRUG: Levetiracetam
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Tamibarotene(AM80H) for HTLV-1 Associated Myelopathy/ Tropical Spastic Paraparesis (HAM/TSP)
Status: UNKNOWN
Conditions: HTLV-I-Associated Myelopathy
Interventions: DRUG: Tamibarotene
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immune-Pineal Axis Function in Fibromyalgia
Status: UNKNOWN
Conditions: Fibromyalgia
Interventions: DRUG: Melatonin and Placebo|DRUG: Amitriptyline and Placebo|DRUG: Melatonin and Amitriptylin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Docetaxel and PROSTVAC for Metastatic Castration-Sensitive Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer|Prostate Neoplasms|Neoplasms, Prostatic
Interventions: BIOLOGICAL: PROSTVAC-V|BIOLOGICAL: PROSTVAC-F|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial to Investigate Long Term Efficacy and Safety of Lonapegsomatropin in Adults With Growth Hormone Deficiency
Status: ACTIVE_NOT_RECRUITING
Conditions: Adult Growth Hormone Deficiency|Endocrine System Diseases|Hormone Deficiency
Interventions: DRUG: Lonapegsomatropin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety to Extend Treatment 24 Weeks in co-Infected HIV-HCV Genotype 1 and/or 4
Status: COMPLETED
Conditions: HIV Infections|Hepatitis C
Interventions: DRUG: Peginterferon alfa-2a + ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Rotigotine in the Treatment of Patients With Early Stage of Primary Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DRUG: LY03003( the name of rotigotine)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Study of BMS-823778 in Subjects With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: BMS-823778|DRUG: BMS-823778|DRUG: BMS-823778|DRUG: Placebo|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Chidamide Plus Sintilimab for Chemotherapy-refractory Advanced High-grade Neuroendocrine Neoplasm
Status: RECRUITING
Conditions: Neuroendocrine Tumors|Neuroendocrine Tumor Grade 3|Neuroendocrine Carcinoma|Neuroendocrine Neoplasm
Interventions: DRUG: Chidamide|DRUG: Sintilimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Longitudinal MR Imaging of Pulmonary Function in Patients Receiving Thoracic Radiation Treatment
Status: COMPLETED
Conditions: Radiation Injury
Interventions: DRUG: Hyperpolarized 129-Xenon gas|DEVICE: MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of Daclizumab (Zenapax) in Combination With Mycophenolate Mofetil (CellCept) and Sirolimus in Prevention of Acute Rejection in Heart Transplant Participants
Status: COMPLETED
Conditions: Heart Transplantation
Interventions: DRUG: Daclizumab|DRUG: Mycophenolate mofetil|DRUG: Silrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Insulin Lispro in Participants With Inadequately Controlled Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Insulin lispro|DRUG: Glargine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Olmsted NAFLD Epidemiology Study (TONES)
Status: RECRUITING
Conditions: Non-Alcoholic Fatty Liver Disease|Non-Alcoholic Steatohepatitis
Interventions: DIAGNOSTIC_TEST: Magnetic Resonance Elastography|OTHER: Blood draw|PROCEDURE: Liver biopsy|PROCEDURE: Fibro Scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Insulin Sensitizer Therapy on Atherothrombotic and Inflammatory Profiles Associated With Insulin Resistance
Status: COMPLETED
Conditions: Type 2 Diabetes|Insulin Resistance|Metabolic Syndrome
Interventions: DRUG: metformin|DRUG: pioglitazone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Alirocumab (SAR236553/REGN727) Versus Placebo on Top of Lipid-Modifying Therapy in Patients With Heterozygous Familial Hypercholesterolemia (ODYSSEY HIGH FH)
Status: COMPLETED
Conditions: Hypercholesterolaemia
Interventions: DRUG: Alirocumab|DRUG: Placebo (for alirocumab)|DRUG: Lipid Modifying Therapy (LMT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Frenotomy of the Labial Frenulum in Infants With Breastfeeding Difficulties
Status: SUSPENDED
Conditions: Breastfeeding
Interventions: PROCEDURE: Lingual Frenulum frenotomy|PROCEDURE: Sham frenotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ticagrelor Versus Cilostazol in Large-vessel Ischemic Stroke
Status: RECRUITING
Conditions: Ischemic Stroke
Interventions: DRUG: Ticagrelor 90 MG|DRUG: Cilostazol 100 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Testing Diet Intervention Versus Non-Diet Intervention for Management of Bowel Symptoms in Rectal Cancer Survivors
Status: COMPLETED
Conditions: Rectal Carcinoma|Rectosigmoid Carcinoma
Interventions: OTHER: Best Practice|DIETARY_SUPPLEMENT: Dietary Intervention|OTHER: Message|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Utility of Digital Dermoscopy in the Skin Cancer Clinic
Status: TERMINATED
Conditions: Skin Cancer|Dermatology/Skin - Other
Interventions: DEVICE: Barco NV Digital Dermatoscope device images|DEVICE: Standard medical photographs including dermoscopy images|OTHER: Clinic proforma completion
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: What is the Nature of Pelvic Floor Muscle Involvement in Dyspareunia?
Status: COMPLETED
Conditions: Dyspareunia
Interventions: DIAGNOSTIC_TEST: Corticomotor excitability to the pelvic floor muscles|DIAGNOSTIC_TEST: Pelvic floor muscle response to pressure applied at the vulvar vestibule|DIAGNOSTIC_TEST: Pressure pain threshold (PPS)|DIAGNOSTIC_TEST: Temporal summation of pain|DIAGNOSTIC_TEST: Tonic, phasic and reflex activation of the pelvic floor muscles (PFMs)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Human Umbilical-Cord-Derived Mesenchymal Stem Cell Therapy in Acute Lung Injury
Status: UNKNOWN
Conditions: Acute Lung Injury|Acute Respiratory Distress Syndrome
Interventions: BIOLOGICAL: UCMSC group
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Use of Low Intensity Shock Wave Therapy for the Treatment of Provoked Vestibulodynia Disorder (PVD)
Status: COMPLETED
Conditions: Provoked Vestibulodynia
Interventions: DEVICE: Shockwave treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability of IBI355 in Patients With Primary Sjogren's Syndrome
Status: RECRUITING
Conditions: Primary Sjögren's Syndrome
Interventions: DRUG: IBI355|DRUG: IBI355 placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of UX003 Recombinant Human Beta-Glucuronidase (rhGUS) Enzyme Replacement Treatment in Mucopolysaccharidosis Type 7, Sly Syndrome (MPS 7) Patients Less Than 5 Years of Age
Status: COMPLETED
Conditions: Sly Syndrome|MPS VII|Mucopolysaccharidosis|Mucopolysaccharidosis VII
Interventions: DRUG: UX003
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing 2 Types of Pain Relief After Cesarean Delivery: Spinal Morphine and TAP Block
Status: COMPLETED
Conditions: Cesarean Delivery
Interventions: PROCEDURE: Placebo block|PROCEDURE: Ultrasound-guided TAP block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase II/III Study of Adebrelimab in Combination With SHR-8068 and Chemotherapy in Advanced or Metastatic NSCLC Patients
Status: NOT_YET_RECRUITING
Conditions: Non-squamous Non-small Cell Lung Cancer
Interventions: DRUG: Adebrelimab + SHR-8068 + Pemetrexed + Carboplatin|DRUG: Camrelizumab + Pemetrexed + Carboplatin|DRUG: Adebrelimab + Pemetrexed + Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Efficacy and Safety Between Pioglitazone and Placebo Added to Combination Therapy in Type 2 Diabetes
Status: UNKNOWN
Conditions: Type 2 Diabetes
Interventions: DRUG: Pioglitazone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Central Nervous System Changes Following BotulinumtoxinA Injection in the Bladder
Status: COMPLETED
Conditions: Multiple Sclerosis|Lower Urinary Tract Symptoms|Neurogenic Bladder|Detrusor, Overactive|Urge Incontinence
Interventions: DRUG: Intradetrusor injection of Botulinum Toxin-A
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Transcranial Direct Current Stimulation for Post-Stroke Aphasia
Status: TERMINATED
Conditions: Stroke
Interventions: BEHAVIORAL: Aphasia therapy|DEVICE: Anodal tDCS|DEVICE: Sham tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Improving Multivitamin Supplementation to Pregnant Women
Status: COMPLETED
Conditions: Pregnancy|Morning Sickness|Nausea|Vomiting|Hyperemesis Gravidarum
Interventions: DRUG: Pregvit®|DRUG: Orifer F®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Acetazolamide on Maximal Exercise Performance in Lowlanders Older Than 40 Years at Altitude
Status: COMPLETED
Conditions: Altitude Hypoxia
Interventions: DRUG: ACETAZOLAMIDE oral capsule|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Immunogenicity of the Dengue Virus Vaccine TV005 (TetraVax-DV TV005) in Healthy Adults, Adolescents, and Children in Dhaka, Bangladesh
Status: COMPLETED
Conditions: Dengue
Interventions: BIOLOGICAL: TV005 vaccine|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Single-center, Prospective Cohort Study on the Differentiation of Benign and Malignant Bile Duct Stenosis Based on Bile and Peripheral Blood cfDNA Methylation Profiles
Status: RECRUITING
Conditions: Bile Duct Neoplasms|Jaundice, Obstructive|Bile Duct Diseases
Interventions: DIAGNOSTIC_TEST: cfDNA methylation detection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Gemcitabine and Topotecan in Treating Patients With Recurrent or Persistent Ovarian, Fallopian Tube, or Primary Peritoneal Cavity Cancer
Status: COMPLETED
Conditions: Fallopian Tube Cancer|Ovarian Cancer|Peritoneal Cavity Cancer
Interventions: DRUG: gemcitabine hydrochloride|DRUG: topotecan hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Iontophoresis-assisted AFL-PDT in Actinic Keratosis
Status: COMPLETED
Conditions: Actinic Keratosis
Interventions: DRUG: lidocaine/prilocaine (5%) application|DEVICE: 2940-nm Er:YAG AFL pretreatment|DRUG: MAL application|DEVICE: Iontophoresis application|DEVICE: irradiation with red light-emitting diode lamp
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity of DTaP-IPV-Hep B-PRP~T Combined Vaccine Compared With PENTAXIM™ and ENGERIX B® at 2-3-4 Months Schedule
Status: COMPLETED
Conditions: Hepatitis B|Polio|Diphtheria|Pertussis
Interventions: BIOLOGICAL: DTaP-IPV-HB-PRP~T vaccine|BIOLOGICAL: DTaP-IPV//PRP~T combined|BIOLOGICAL: Hepatitis B vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Ultrasound Imaging of the Larynx and Diaphragm During NIV and Cough Assist
Status: COMPLETED
Conditions: Healthy Persons
Interventions: DIAGNOSTIC_TEST: Diagnostic Ultrasound|DIAGNOSTIC_TEST: Transnasal Fiberoptic Laryngoscopy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: MEtronomic TrEatment Option in Advanced bReast cAncer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Paclitaxel|DRUG: Cyclophosphamide|DRUG: Capecitabine|DRUG: Vinorelbine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: European Bifurcation Club Trial - Two-stent Versus One-stent Technique for Large Bifurcation Lesions
Status: COMPLETED
Conditions: Coronary Disease
Interventions: DEVICE: single stent|DEVICE: two stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of AdCh63 AMA1 Alone and With MVA AMA1
Status: COMPLETED
Conditions: Malaria
Interventions: BIOLOGICAL: AdCh63 AMA1|BIOLOGICAL: AdCh63 AMa1 and MVA AMA1
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Quantitative Superior Vena Cava Isolation in Addition to Pulmonary Vein Isolation for Paroxysmal Atrial Fibrillation
Status: RECRUITING
Conditions: Atrial Fibrillation
Interventions: PROCEDURE: PVI|PROCEDURE: PVI+ quantitative SVCI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cetuximab as Salvage Therapy in Patients With Neo Wild-type RAS/RAF Metastatic Colorectal Cancer With Liver Metastases.
Status: RECRUITING
Conditions: Cancer Colorectal
Interventions: DRUG: Cetuximab|DRUG: Irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial to Assess Brexpiprazole Versus Placebo for the Treatment of Acute Manic Episodes Associated With Bipolar I Disorder
Status: COMPLETED
Conditions: Bipolar I Disorder|Manic Episode
Interventions: DRUG: Brexpiprazole|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sequential Genicular Nerve Ablation Prior to Geniculate Artery Embolization in Knee Pain
Status: NOT_YET_RECRUITING
Conditions: Chronic Knee Pain|Osteoarthritis
Interventions: PROCEDURE: GNA followed by GAE|PROCEDURE: GAE alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of MK-7145 Compared to Placebo and Hydrochlorothiazide for Lowering Blood Pressure in Male Participants With Hypertension (MK-7145-009)
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: MK-7145|DRUG: Hydrochlorothiazide (HCTZ)|DRUG: Placebo to MK-7145|DRUG: Placebo to HCTZ
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Safety and Activity of F14 for Management of Pain Following Total Knee Replacement
Status: COMPLETED
Conditions: Total Knee Replacement|Postoperative Pain
Interventions: DRUG: Bupivacaine HCl|DRUG: F14 (celecoxib)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Everolimus and Vatalanib in Treating Patients With Advanced Solid Tumors
Status: COMPLETED
Conditions: Gastrinoma|Glucagonoma|Insulinoma|Metastatic Gastrointestinal Carcinoid Tumor|Metastatic Pheochromocytoma|Pancreatic Polypeptide Tumor|Recurrent Gastrointestinal Carcinoid Tumor|Recurrent Islet Cell Carcinoma|Recurrent Melanoma|Recurrent Neuroendocrine Carcinoma of the Skin|Recurrent Non-small Cell Lung Cancer|Recurrent Pheochromocytoma|Recurrent Renal Cell Cancer|Somatostatinoma|Stage III Neuroendocrine Carcinoma of the Skin|Stage IV Melanoma|Stage IV Non-small Cell Lung Cancer|Stage IV Renal Cell Cancer|Thyroid Gland Medullary Carcinoma|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: everolimus|DRUG: vatalanib|OTHER: pharmacological study|OTHER: laboratory biomarker analysis|PROCEDURE: dynamic contrast-enhanced magnetic resonance imaging|PROCEDURE: ultrasound imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Mucolytic Solution Before Upper Endoscopy
Status: UNKNOWN
Conditions: Gastric Cancer|Gastroscopy
Interventions: DRUG: Espumisan, N acetylcystein|DRUG: Espumisan, N acetylcystein|DRUG: Water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Results Following Fresh-frozen Humeral Head Osteochondral Allograft Reconstruction for Reverse Hill-Sachs Lesion
Status: ACTIVE_NOT_RECRUITING
Conditions: Shoulder Dislocation Closed Traumatic
Interventions: PROCEDURE: fresh-frozen humeral head osteochondral allograft reconstruction for reverse Hill-Sachs lesion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Kazakh Version of Reflux Symptom Index
Status: COMPLETED
Conditions: Laryngopharyngeal Reflux Symptoms|Laryngopharyngitis Chronic|Gastro Esophageal Reflux Disease
Interventions: OTHER: Reflux Symptom Index Inventory (diagnostic survey)|OTHER: Reflux finding score
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Combined Behavioral and Pharmacological Intervention for Cardiovascular Risk Reduction in Diabetic Patients
Status: COMPLETED
Conditions: Diabetes|Hypertension|Dyslipidemia|Coronary Arteriosclerosis
Interventions: BEHAVIORAL: Behavioral counseling and peer support|BEHAVIORAL: Interactive Education|BEHAVIORAL: Role modeling|PROCEDURE: Pharmacologic case management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Safety, Tolerability and Pharmacokinetics of HZ-A-018 in Patients With B Cell Lymphoma
Status: UNKNOWN
Conditions: Lymphoma, B-Cell
Interventions: DRUG: HZ-A-018
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 2 Doses of an Approved Drug Being Studied for a New Indication for the Prevention of Postoperative Nausea and Vomiting (0869-090)(COMPLETED)
Status: COMPLETED
Conditions: Postoperative Nausea and Vomiting
Interventions: DRUG: MK0869, aprepitant|DRUG: Comparator: ondansetron IV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Probiotic Added to Maternal Diet on Infantile Colic and Intestinal Microbiota Content
Status: COMPLETED
Conditions: Infantile Colic|Microbial Colonization|Crying
Interventions: DIETARY_SUPPLEMENT: Activia Probiotics Shot|OTHER: Routine care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Sorafenib and Letrozole, Anastrozole, or Exemestane in Treating Postmenopausal Women With Estrogen Receptor-Positive and/or Progesterone Receptor-Positive Metastatic Breast Cancer
Status: TERMINATED
Conditions: Breast Cancer
Interventions: DRUG: anastrozole|DRUG: exemestane|DRUG: letrozole|DRUG: sorafenib tosylate|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Early Administration of Heparin at FMC for PPCI of STEMI Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: STEMI|Primary PCI
Interventions: DRUG: Heparin Sodium Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prevention Trial to Achieve Cardiovascular Targets
Status: COMPLETED
Conditions: Coronary Artery Disease|Peripheral Arterial Disease|Hyperlipidemia|Hypertension|Diabetes|Prediabetes|Obesity
Interventions: BEHAVIORAL: Prevention Consult|BEHAVIORAL: Consult & Behavioral Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pirfenidone Treat Myocardial Fibrosis After Acute Myocardial Infarction
Status: ACTIVE_NOT_RECRUITING
Conditions: Myocardial Fibrosis
Interventions: DRUG: Pirfenidone Oral Capsule|OTHER: Placebo Oral Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Safety and Efficacy of Renagel® Compared With Calcium Acetate in Patients With Peritoneal Dialysis
Status: COMPLETED
Conditions: Peritoneal Dialysis|Chronic Kidney Disease
Interventions: DRUG: Sevelamer Hydrochloride (Renagel®)|DRUG: Calcium acetate (PhosLo® )
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Management of Anticoagulant Therapy Monitored by an Implantable Device With Telecardiology in Patients With Acute Coronary Syndrome Associated With de Novo Atrial Fibrillation Arrhythmia
Status: RECRUITING
Conditions: Atrial Fibrillation, Myocardial Infarction
Interventions: DRUG: non-systematic prescription of anticoagulant therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics (PK) of Dalfampridine-ER 7.5 mg BID in Healthy Volunteers and Subjects With Mild or Moderate Renal Impairment
Status: COMPLETED
Conditions: Renal Insufficiency
Interventions: DRUG: Dalfampridine-ER
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Harlem Strong Mental Health Coalition
Status: RECRUITING
Conditions: Stress-related Problem|Depression, Anxiety|Mental Health Wellness
Interventions: BEHAVIORAL: MH task-sharing training|BEHAVIORAL: Supervision|BEHAVIORAL: Learning Collaborative|OTHER: Technology Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Drug-drug Interaction Study of SPH3127
Status: COMPLETED
Conditions: Drug Drug Interaction
Interventions: DRUG: SPH3127 tablet|DRUG: Itraconazole|DRUG: SPH3127 tablet|DRUG: Rifampin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Telomere-telomerase System and the Expression of Candidate Genes in the Leukocytes of Patients With Depressive Disorder: Search for Peripheral Markers of Somatic Stress
Status: UNKNOWN
Conditions: Depressive Disorder
Interventions: OTHER: telomere length
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Effectiveness of Acupuncture as an Adjunct to Rehabilitation After Knee Arthroplasty
Status: UNKNOWN
Conditions: Total Knee Replacement
Interventions: PROCEDURE: Acupuncture|PROCEDURE: exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT