pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Effectiveness of Cat-PAD to Treat Cat Allergy in Cat Allergic Subjects
Status: COMPLETED
Conditions: Cat Allergy
Interventions: BIOLOGICAL: Cat-PAD|BIOLOGICAL: Cat-PAD|BIOLOGICAL: Cat-PAD|BIOLOGICAL: Cat-PAD|BIOLOGICAL: Cat-PAD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Role of Music Listening in Gastrointestinal Endoscopy
Status: UNKNOWN
Conditions: Gastrointestinal Endoscopic Procedures
Interventions: BEHAVIORAL: Music listening
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Phase 1a, Double-Blind, Placebo-Controlled, Single Ascending Dose Study to Evaluate Lpathomab in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: BIOLOGICAL: 0.5 mg/kg Lpathomab|BIOLOGICAL: 1.0 mg/kg Lpathomab|BIOLOGICAL: 3.0 mg/kg Lpathomab|BIOLOGICAL: 10 mg/kg Lpathomab|BIOLOGICAL: 20 mg/kg Lpathomab|OTHER: Saline solution for intravenous infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PK Study of Anti-TB Drugs
Status: COMPLETED
Conditions: Tuberculosis
Interventions: DRUG: Isoniazid (H)|DRUG: Rifampicin (R)|DRUG: Pyrazinamide (Z)|DRUG: Ethambutol (E)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Exercise on Dialysis Patients' Survival
Status: COMPLETED
Conditions: Kidney Disease, Chronic|End Stage Renal Disease|Hemodialysis
Interventions: OTHER: Intradialytic Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: TRIGEN SURESHOT™ Distal Targeting System Study
Status: TERMINATED
Conditions: Femoral Shaft Fracture
Interventions: DEVICE: TRIGEN SURESHOT Distal Targeting Instrumentation.|OTHER: Free-hand technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of Inhaled Mannitol and rhDNase in Children With Cystic Fibrosis
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: mannitol|DRUG: mannitol + pulmozyme|DRUG: Dornase alpha
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Therapy of Scars and Cutis Laxa With Autologous Adipose Derived Mesenchymal Stem Cells
Status: COMPLETED
Conditions: Skin|Scar|Cutis Laxa|Keloid|Cicatrix
Interventions: PROCEDURE: Laser therapy|BIOLOGICAL: Autologous ADSC injection|PROCEDURE: Normal saline injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Enhanced Recovery After Surgery for Anterior Cervcial Spine Surgeries in Elderly Patients
Status: UNKNOWN
Conditions: Other Fusion of Spine, Cervical Region
Interventions: DRUG: Sugammadex Injection|DRUG: Neostigmine Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: ForgIng New Paths to Prevent DIabeTes (FINDIT)
Status: COMPLETED
Conditions: Prediabetes
Interventions: BEHAVIORAL: Blood Test Group Intervention|BEHAVIORAL: Brochure Group Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Study Assessing Effects of JZP-110 on Driving Performance in the Treatment of Excessive Sleepiness in Narcolepsy
Status: COMPLETED
Conditions: Narcolepsy|Excessive Sleepiness
Interventions: DRUG: JZP-110|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Dexamethasone to Improve Clinical Outcomes in Coronary Artery Bypass Patients
Status: COMPLETED
Conditions: Coronary Artery Disease|Inflammatory Response
Interventions: DRUG: Dexamethasone|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Mediterranean Approach to Low FODMAP Diet (MED-LFD) for Managing IBS Symptoms
Status: COMPLETED
Conditions: Irritable Bowel Syndrome With Diarrhea
Interventions: OTHER: Med-LFD|OTHER: Nutritional Guidelines of the British National Institute for Health and Care Excellence (NICE) Managing IBS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy, Immunogenicity and Safety of BBIBP-CorV Vaccine Against Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection.
Status: NOT_YET_RECRUITING
Conditions: COVID-19 Disease
Interventions: BIOLOGICAL: BBIBP-CorV - Inactivated SARS-CoV-2 vaccine (Vero cell)|BIOLOGICAL: influenza season quadrivalent Influenza Vaccine (Flu Quadrivalent)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Study of Olaparib in Newly Diagnosed mCRPC Patients With HRR Gene Mutation
Status: UNKNOWN
Conditions: Prostate Cancer|Prostate Carcinoma|Metastatic Castration-resistant Prostate Cancer
Interventions: DRUG: Olaparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of Group Interpersonal Synchrony in Young Autistic Adults' Work Environment
Status: COMPLETED
Conditions: Autism Spectrum Disorder
Interventions: BEHAVIORAL: Structured synchronous physical training|BEHAVIORAL: Structured non-synchronous physical training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Abemaciclib and Elacestrant in Patients With Brain Metastasis Due to ER+/HER-2- Breast Cancer
Status: RECRUITING
Conditions: Breast Neoplasms|Brain Neoplasms|Neoplasms by Site|Neoplasms|Breast Diseases|Central Nervous System Neoplasms|Brain Diseases|Central Nervous System Diseases
Interventions: DRUG: Elacestrant|DRUG: Abemaciclib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study of DWP-450 (Botulinum Toxin, Type a) to Treat Glabellar Lines - EV-006
Status: COMPLETED
Conditions: Glabellar Frown Lines
Interventions: BIOLOGICAL: DWP-450 (Botulinum purified neurotoxin, Type A)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Targeted Hypothermia Versus Targeted Normothermia After Out-of-hospital Cardiac Arrest
Status: COMPLETED
Conditions: Out-of-hospital Cardiac Arrest
Interventions: PROCEDURE: Targeted temperature management to 33°C|PROCEDURE: Standard care with early treatment of fever
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of MTBF Conditioning Regimen for Salvageable Allo-HSCT in the Treatment of R/R AML
Status: NOT_YET_RECRUITING
Conditions: Relapse Leukemia|Refractory Acute Myeloid Leukemia|Conditioning|Hematopoietic Stem Cell Transplantation
Interventions: DRUG: MTBF regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: H-Type Hypertension Precision Medicine Trial
Status: UNKNOWN
Conditions: Hypertension
Interventions: DRUG: Folic Acid|DRUG: Enalapril Maleate and Folic Acid Tablets (Yiye)|DRUG: Enalapril
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Assessing Choice in the Employer Setting (ACES) Study
Status: COMPLETED
Conditions: Healthy
Interventions: BIOLOGICAL: Choice of TIV or FluMist with baseline advertisement|OTHER: Choice of TIV or FluMist with enhanced advertisement and incentives|BIOLOGICAL: Control - Usual care offering TIV only with baseline advertisement
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Assess the Food Effect and the Relative Bioavailability of the Cabotegravir (CAB) Pediatric Dispersible Tablet (DT) Formulation
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Cabotegravir IR Formulation (reference)|DRUG: Cabotegravir DT Formulation (test 1)|DRUG: Cabotegravir DT Formulation (test 2)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Evaluate the Pharmacokinetics and Safety of AD-208
Status: COMPLETED
Conditions: Androgenetic Alopecia
Interventions: DRUG: AD-208|DRUG: Avodart Soft Capsule 0.5mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Angiotech Vascular Wrap Paclitaxel-Eluting Mesh for Hemodialysis Vascular Access
Status: TERMINATED
Conditions: Kidney Diseases|ESRD
Interventions: DEVICE: Vascular Wrap Paclitaxel-Eluting Mesh|DEVICE: Lifespan® ePTFE Vascular Graft|DEVICE: Lifespan® ePTFE Vascular Graft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Treatment for Symptomatic Peripheral Neuropathy in Patients With Diabetes
Status: COMPLETED
Conditions: Diabetic Neuropathies|Diabetes Mellitus, Insulin-Dependent|Diabetes Mellitus, Non-Insulin-Dependent
Interventions: DRUG: Ruboxistaurin mesylate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Acupressure in Managing Opioid-induced Constipation
Status: UNKNOWN
Conditions: Opioid-induced Bowel Dysfunction|Constipation Drug Induced
Interventions: OTHER: Accupressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Phase II Study of Epigenetic Therapy to Overcome Chemotherapy Resistance in Refractory Solid Tumors
Status: COMPLETED
Conditions: Refractory Solid Tumors
Interventions: DRUG: Hydralazine and magnesium valproate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Growth of Infants Fed New Starter Formula
Status: COMPLETED
Conditions: Dietary Intervention
Interventions: OTHER: test starter infant formula|OTHER: test starter infant formula with synbiotics|OTHER: control standard formula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: RCT: Trazodone vs Quetiapine vs Placebo for Treating ICU Delirium (TraQ)
Status: NOT_YET_RECRUITING
Conditions: Delirium|Morality|Quality of Life|Psych|Treatment Side Effects
Interventions: DRUG: Trazodone|DRUG: Quetiapine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Research Study Investigating Mim8 in People With Haemophilia A
Status: COMPLETED
Conditions: Healthy Volunteers|Haemophilia A With or Without Inhibitors
Interventions: DRUG: NNC0365-3769 (Mim8)|DRUG: Placebo (Mim8)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: RIB PAIN (Rib Fractures Treated With Parental Analgesia With Infused LidocaiNe)
Status: UNKNOWN
Conditions: Rib Fracture Multiple|Pain, Chest|Pain, Acute|Respiratory Failure|Thoracic Injuries|Trauma Chest
Interventions: DRUG: Intervention: Lidocaine|DRUG: Control: Standard Care + Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Faecal Microbiota Transplantation to Ameliorate Nintedanib-induced Diarrhea in Patients With Idiopathic Pulmonary Fibrosis
Status: NOT_YET_RECRUITING
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: PROCEDURE: Autologous FMT|PROCEDURE: Placebo FMT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cardiac Safety of Indacaterol
Status: COMPLETED
Conditions: Healthy Volunteers|Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Indacaterol 150 µg|DRUG: Indacaterol 300 µg|DRUG: Indacaterol 600 µg|DRUG: Placebo|DRUG: Placebo/moxifloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparison of the Control of Asthma Provided by Symbicort® Turbuhaler® Versus Symbicort® Turbuhaler® Plus Pulmicort® Turbuhaler® Plus Terbutaline Turbuhaler®
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Budesonide/Formoterol Turbuhaler|DRUG: Budesonide Turbuhaler (Pulmicort)|DRUG: Terbutaline Turbuhaler
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Impact of Management Strategies on Gastrointestinal-Related Adverse Events in Participants With Non-Small Cell Lung Cancer Harboring Epidermal Growth Factor Receptor (EGFR) Exon 20 Insertion Mutations Receiving TAK-788
Status: WITHDRAWN
Conditions: Non-Small Cell Lung Cancer (NSCLC)
Interventions: DRUG: TAK-788|DRUG: Antidiarrheal prophylaxis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety Study of MT10107 in the Treatment of Glabella Line
Status: COMPLETED
Conditions: Glabellar Frown Lines
Interventions: DRUG: Botox (Botulinum toxin type A)|DRUG: MT10107 (Botulinum toxin type A)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Retrospective Study of the Results of Cooled Radiofrequency for Genicular Nerves Neurotomy in 40 Consecutive Patients With Osteoarthritis of the Knee and Painful Knee Arthroplasty
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: PROCEDURE: cooled radiofrequency ablation of genicular nerves
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Novel Application of 2% Lidocaine Injection for Male Rigid cycstoscopy-a Patient-blinded Randomised Trial
Status: WITHDRAWN
Conditions: Bladder Cancer
Interventions: DRUG: Intraurethral lidocaine gel alone|DRUG: Intraurethral lidocaine gel + lidocaine 2% injection|DRUG: intraurethral lidocaine gel + liquid paraffinl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Controlled Study of Olanzapine in Children With Autism
Status: COMPLETED
Conditions: Autistic Disorder
Interventions: DRUG: olanzapine (Zyprexa)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study With Berberine-based Food Supplement, Artichoke Extract, Phytosterols, Fenugreek and SelectSIEVE® OptiChol
Status: RECRUITING
Conditions: Dyslipidemias
Interventions: DIETARY_SUPPLEMENT: Berberine-based Food Supplement, Artichoke Extract, Phytosterols, Fenugreek and SelectSIEVE® OptiChol|DIETARY_SUPPLEMENT: Berberine-based Food Supplement, Artichoke Extract, Phytosterols, Fenugreek and SelectSIEVE® OptiChol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Dr.Reddy's Ibuprofen and Diphenhydramine Citrate 200 mg/38 mg Caplets Under Fasting Condition
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Ibuprofen and Diphenhydramine Citrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clozapine and Olanzapine Treatment of Aggression
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Clozapine|DRUG: Olanzapine|DRUG: Haloperidol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Physiotherapy in the Treatment of Lymphedema After Breast Cancer
Status: COMPLETED
Conditions: Lymphedema of Upper Limb
Interventions: PROCEDURE: Manual lymphatic drainage|PROCEDURE: Manual lymphatic drainage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Phase 1/2 Study of the Safety and Efficacy of Rociletinib in Combination With Trametinib in Patients With mEGFR-positive Advanced or Metastatic Non-small Cell Lung Cancer
Status: TERMINATED
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: Rociletinib|DRUG: Trametinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Performance of Different Adhesive Strategies With a Universal System in Sclerosed Dentin in NCCL: A Double-blind Randomized Clinical Trial.
Status: UNKNOWN
Conditions: Sclerotic Dentine|Non Carious Cervical Lesion
Interventions: PROCEDURE: Composite resin restoration with Self Etch adhesive protocol and absence of sclerotic dentin|PROCEDURE: Composite resin restoration with Seletive enamel etch adhesive protocol and absence of sclerotic dentin|PROCEDURE: Composite resin restoration with Self Etch adhesive protocol and presence of sclerotic dentin|PROCEDURE: Composite resin restoration with Seletive enamel etch adhesive protocol and presence of sclerotic dentin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Pharmacokinetics of Mucinex 600 mg Extended-release Bi-layer Tablet in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: Mucinex® ER 600 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of Experimental Medication BMS-986036 Given to Healthy Participants
Status: COMPLETED
Conditions: Hepatic Cirrhosis|Liver Fibrosis|Nonalcoholic Fatty Liver Disease|Nonalcoholic Steatohepatitis
Interventions: DRUG: BMS-986036
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: AZD2171 and Standard Combination Chemotherapy in Advanced Non-Small Cell Lung Cancer or Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer|Lung Cancer
Interventions: DRUG: cediranib maleate|DRUG: cisplatin|DRUG: fluorouracil|DRUG: gemcitabine hydrochloride|DRUG: leucovorin calcium|DRUG: oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Kyphoplasty and Vertebroplasty in the Treatment of Spine Metastases
Status: TERMINATED
Conditions: Solid Tumors|Spine Metastasis
Interventions: DEVICE: Kyphoplasty|DEVICE: Conventional vertebroplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Trial of Financial Incentives to Reduce Sugar-sweetened Beverage Purchases by Low-income, Latino Families
Status: COMPLETED
Conditions: Obesity Prevention
Interventions: BEHAVIORAL: Targeted beverage education and financial incentives|BEHAVIORAL: Traffic-light labeling of all beverages in store
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Analgesic Effect of Pulmonary Recruitment and Intraperitoneal Hydrocortisone in Laparoscopic Gynecological Surgery
Status: UNKNOWN
Conditions: Laparoscopic Gynecological Surgery
Interventions: COMBINATION_PRODUCT: Pulmonary Recruitment Maneuver
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Reiki/Energy Healing in Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: BEHAVIORAL: Reiki|BEHAVIORAL: Pretend Reiki|BEHAVIORAL: Rest / Guided Imagery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Basiliximab, Delayed Dose Tacrolimus Plus ECMPA (Enteric Coated Mycophenolic Acid) Following Liver Transplantation
Status: COMPLETED
Conditions: Liver Transplantation
Interventions: DRUG: Basiliximab|DRUG: Tacrolimus|DRUG: Tacrolimus|DRUG: Mycophenolic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pleurodesis Using Hypertonic Glucose to Treat Post-operative Air Leaks
Status: COMPLETED
Conditions: Postoperative Air Leak
Interventions: DRUG: 50 mL of 50% Glucose|DRUG: 100 mL of 50% Glucose|DRUG: 150 mL of 50% Glucose|DRUG: 200 mL of 50% Glucose
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rapamycin Therapy for Patients With Tuberous Sclerosis Complex and Sporadic LAM
Status: COMPLETED
Conditions: Tuberous Sclerosis|Lymphangioleiomyomatosis
Interventions: DRUG: Rapamycin, sirolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating Safety and Efficacy of Umbulizer in Patients Requiring Intermittent Positive Pressure Ventilation
Status: COMPLETED
Conditions: Respiratory Failure|Respiratory Insufficiency|Respiratory Arrest
Interventions: DEVICE: Umbulizer|DEVICE: Traditional Mechanical Ventilator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Photobiomodulation Therapy Plus M-health in Head and Neck Cancer Patients: LAXER Study
Status: RECRUITING
Conditions: Head and Neck Cancer|Head and Neck Neoplasms|Xerostomia
Interventions: DEVICE: Energy density photobiomodulation (7.5)|DEVICE: Energy density photobiomodulation (3)|DEVICE: Sham placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: To Evaluate the Pharmacokinetics and Safety of Yimitasvir Phosphate Capsules in Subjects With Moderate and Severe Liver Function Impairment and in Healthy Subjects
Status: COMPLETED
Conditions: Hepatic Impairment
Interventions: DRUG: Yimitasvir Phosphate|DRUG: Yimitasvir Phosphate|DRUG: Yimitasvir Phosphate|DRUG: Yimitasvir Phosphate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Manual Physical Therapy During Pregnancy on Post Partum Perineal Trauma and Pain
Status: ACTIVE_NOT_RECRUITING
Conditions: Pregnancy Related|Delivery; Injury, Maternal|Pelvic Floor Disorders
Interventions: BEHAVIORAL: manual physical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dexamethasone With Super-hydration for Prevention of Postoperative Nausea and Vomiting
Status: COMPLETED
Conditions: Nausea and Vomiting, Postoperative
Interventions: DRUG: Dexamethasone|DRUG: 10 ml/kg Ringer's lactate|DRUG: 30 ml/kg Ringer's lactate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study to Evaluate the Safety and Preliminary Efficacy of IDCT, a Treatment for Symptomatic Lumbar Intervertebral Disc Degeneration
Status: COMPLETED
Conditions: Degenerative Disc Disease
Interventions: BIOLOGICAL: IDCT|DRUG: Saline Solution|DRUG: Sodium Hyaluronate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial to Evaluate Efficacy of Once or Twice ZOledronic Acid After Different Duration of denOsumMab Administration in Postmenopausal Women With Osteoporosis (ZOOM Study)
Status: UNKNOWN
Conditions: Osteoporosis
Interventions: DRUG: Zoledronic acid, once|DRUG: Zoledronic acid, twice
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Social Media as an Information, Education and Communication Tool for Rabies Prevention: An Interventional Study
Status: COMPLETED
Conditions: Rabies|Health Education|Public Health|Preventive Health Services
Interventions: OTHER: Rabies Information Education and Communication Material
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Art Therapy and Emotional Well Being in Military Populations With Posttraumatic Stress Symptoms
Status: RECRUITING
Conditions: PTSD|Military Activity|Post-Traumatic Headache|Posttraumatic Stress Disorder|Posttraumatic Stress Disorder, Delayed Onset|Sleep Disturbance|Nightmare|Irritable Mood|Anger|Combat and Operational Stress Reaction|Combat Stress Disorders|Military Family|Military Operations
Interventions: BEHAVIORAL: Art Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Narrative Communication Intervention to Increase Human Papillomavirus Vaccination Intentions and Uptake
Status: UNKNOWN
Conditions: Human Papilloma Virus|Intention|Behavior
Interventions: BEHAVIORAL: Common Sense Model Guided Narrative Video
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Risk and Clinical Benefit of Chemotherapy and Intensive Endocrine Therapy for Luminal B1 Early-stage Breast Cancer
Status: UNKNOWN
Conditions: Breast Cancer|Chemotherapy|Endocrine Breast Diseases
Interventions: DRUG: Epirubicin|DRUG: Cyclophosphamide|DRUG: Docetaxel|DRUG: Goserelin acetate|DRUG: Tamoxifen|DRUG: Letrozole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Dose Response Study of Dabigatran Etexilate(BIBR 1048) in Pharmacodynamics and Safety in Patients With Non-valvular Atrial Fibrillation in Comparison to Warfarin
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DRUG: Dabigatran etexilate|DRUG: Dabigatran etexilate|DRUG: Warfarin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy of Fremanezumab for Migraine in Adult CADASIL
Status: WITHDRAWN
Conditions: Cadasil|Migraine
Interventions: DRUG: Fremanezumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Efficacy and Safety, Tolerability and Pharmacokinetics of Telbivudine in Children and Adolescents With Compensated Chronic Hepatitis B Virus Infection
Status: TERMINATED
Conditions: Chronic Hepatitis B
Interventions: DRUG: Telbivudine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vascularized Versus Non-Vascularized Bone Grafts in Treating Proximal Pole Scaphoid Non Unions
Status: UNKNOWN
Conditions: Scaphoid Non-Unions
Interventions: PROCEDURE: Vascularized Bone Graft|PROCEDURE: Non-Vascularized Bone Graft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HEPLISAV-B Hepatitis B Vaccine in Chronic Lymphocytic Leukemia (CLL) and CLL Treated With Bruton's-Tyrosine Kinase Inhibitor (BTK-I)
Status: COMPLETED
Conditions: Hepatitis|Safety and Tolerability
Interventions: BIOLOGICAL: HEPLISAV-B
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Recombinant FSH/GnRH Antagonist Protocol With and Without LH Adjunct for Egg Bank Donation
Status: COMPLETED
Conditions: Egg Donation
Interventions: DRUG: Follistim|DRUG: Ganirelix|DRUG: Menotropins|DRUG: Leuprolide|PROCEDURE: Transvaginal ultrasound guided needle aspiration of oocytes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study To Determine The Efficacy And Safety Of Tigecycline Compared With Imipenem/Cliastatin to Treat Complicated Intra-Abdominal Infection
Status: COMPLETED
Conditions: Intra-abdominal Infection
Interventions: DRUG: Tigecycline|DRUG: Imipenem/cilastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ethosomal Gel Bearing Losartan 5% for Keloid Treatment
Status: NOT_YET_RECRUITING
Conditions: Keloid
Interventions: DRUG: Ethosomal gel bearing losartan 5%|DRUG: triamcinolone acetonide 10 mg/ml
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hypofractionated Radiotherapy in Prostate Cancer Patients Aged 75 Years or Older.
Status: TERMINATED
Conditions: Prostate Cancer|Radiotherapy Side Effect
Interventions: RADIATION: Hypofractionated radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Balance, Autonomic Response, and Sensory Modulation to Dosage of Mechanical Vagal Stimulation in Healthy Adults
Status: NOT_YET_RECRUITING
Conditions: Vagus Nerve Autonomic Disorder|Heart Rate|Pain|Equilibrium; Disorder, Labyrinth|Microbial Colonization
Interventions: OTHER: mechanical Vagus Nerve Stimulation (Low Intensity)|OTHER: mechanical Vagus Nerve Stimulation (Intermediate Intensity)|OTHER: mechanical Vagus Nerve Stimulation (High Intensity)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Carfilzomib and Melphalan Before Stem Cell Transplant in Treating Patients With Multiple Myeloma
Status: COMPLETED
Conditions: DS Stage I Plasma Cell Myeloma|DS Stage II Plasma Cell Myeloma|DS Stage III Plasma Cell Myeloma|Refractory Plasma Cell Myeloma
Interventions: PROCEDURE: Autologous Bone Marrow Transplantation|PROCEDURE: Autologous Hematopoietic Stem Cell Transplantation|DRUG: Carfilzomib|OTHER: Laboratory Biomarker Analysis|DRUG: Melphalan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of a New Behavioral Treatment for Premature Ejaculation Using a Masturbation Aid Device: Star-Stop 3.0
Status: COMPLETED
Conditions: Premature Ejaculation|Cognitive-Behavior Treatment|Masturbation Aid Device
Interventions: DEVICE: Exercise Programme +device+ lubricant|BEHAVIORAL: Exercise Programme + lubricant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Post-Operative Interventions on Surgical Site Occurrences in AWR
Status: RECRUITING
Conditions: Abdomen Hernia
Interventions: DEVICE: Prevena|DEVICE: Prineo|DRUG: Traditional
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy, Safety and Pharmacokinetics of Teriflunomide in Pediatric Patients With Relapsing Forms of Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DRUG: Teriflunomide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Quit and Win Contests to Improve Smoking Cessation Among College Students
Status: COMPLETED
Conditions: Tobacco Use Cessation
Interventions: BEHAVIORAL: Standard contest (1 month)|BEHAVIORAL: Motivational and Problem-Solving|BEHAVIORAL: Extended Contests
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Fasting Study of Lamotrigine Tablets 25 mg to Lamictal® Tablets 25 mg
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Lamotrigine Tablets 25 mg|DRUG: Lamictal® Tablets 25 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Impact of Intraoperative Stretching Microbreaks on Otolaryngologists
Status: UNKNOWN
Conditions: Postural; Strain
Interventions: BEHAVIORAL: Otolaryngology stretching micro-breaks (OSMB)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: RAD001 With Weekly Cisplatin and Radiation Therapy in Patients With Locally Advanced Head and Neck Cancer
Status: TERMINATED
Conditions: Head and Neck Cancer
Interventions: RADIATION: Intensity modulated radiotherapy|DRUG: RAD001|DRUG: cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Effects of a Novel Ovarian Stimulation Regimen on Embryo Aneuploidy Rates in In Vitro Fertilization (IVF)
Status: TERMINATED
Conditions: In Vitro Fertilization
Interventions: DRUG: Ovarian stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sublingual Misoprostol Versus Standard Surgical Care for the Treatment of Incomplete Abortion in Nigeria
Status: COMPLETED
Conditions: Incomplete Abortion
Interventions: DRUG: Misoprostol|PROCEDURE: surgery Manual vacuum aspiration (MVA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Absorption and Metabolism of Dietary Cocoa Procyanidins in Humans
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: Flavanol- and procyanidins-containing drink|OTHER: Procyanidins-containing drink|OTHER: Flavanol-containing drink
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Clincal Study of Reduced Target Radiotherapy in Nasopharyngeal Carcinoma
Status: RECRUITING
Conditions: Toxicity Due to Radiotherapy|Nasopharyngeal Carcinoma
Interventions: RADIATION: Target range
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Tideglusib in Adolescent and Adult Patients With Myotonic Dystrophy
Status: COMPLETED
Conditions: Myotonic Dystrophy 1
Interventions: DRUG: Tideglusib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Impact of NIRS-guided Cardiopulmonary Resuscitation After Cardiac Arrest on Resuscitation Rate
Status: ACTIVE_NOT_RECRUITING
Conditions: Cardiac Arrest|Cardiopulmonary Arrest With Successful Resuscitation|Cerebral Oxygenation
Interventions: COMBINATION_PRODUCT: Cerebral oximetry (near infrared) based CPR-Algorithm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Ultrasound-guided Transversus Abdominis Plane Block After Laparoscopic Bariatric Surgery
Status: UNKNOWN
Conditions: Postoperative Nausea and Vomiting|Postoperative Pain
Interventions: DRUG: Normal saline|DRUG: Ropivacaine at high concentration|DRUG: Ropivacaine and dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Calcitriol and Gefitinib With or Without Dexamethasone in Treating Patients With Advanced Solid Tumors
Status: COMPLETED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DIETARY_SUPPLEMENT: calcitriol|DRUG: dexamethasone|DRUG: gefitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: |Primary Purpose: TREATMENT
Clinical trial: A Study of MDX-010 (BMS-734016) Administered With or Without Prophylactic Oral Budesonide
Status: COMPLETED
Conditions: Malignant Melanoma
Interventions: DRUG: Ipilimumab+ Placebo|DRUG: Ipilimumab+ Budesonide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: MRG-001 in Patients With Amyotrophic Lateral Sclerosis
Status: NOT_YET_RECRUITING
Conditions: Amyotrophic Lateral Sclerosis|Lou Gehrig Disease|Motor Neuron Disease|Motor Neuron Atrophy
Interventions: DRUG: MRG-001
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Trial of Curcumin Effects on Cognition in Schizophrenia
Status: TERMINATED
Conditions: Schizophrenia|Schizoaffective Disorder
Interventions: DIETARY_SUPPLEMENT: curcumin 1800mg|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Determine if Aquamin (as AquaCal and AquaPT) Improves Digestive Discomfort
Status: COMPLETED
Conditions: Digestive System Disorders
Interventions: DIETARY_SUPPLEMENT: AquaCal|DIETARY_SUPPLEMENT: AquaPT|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intrauterine Injection of Human Chorionic Gonadotropin Injection (hCG) Before Embryo Transfer on Pregnancy Outcomes in Frozen Embryo Transfer Cycles.
Status: COMPLETED
Conditions: Infertility
Interventions: DRUG: Intra uterine injection of tissue culture medium containing HCG+ET|DRUG: Intra uterine injection of tissue culture medium +ET|PROCEDURE: ET
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Immersive Virtual Environments and Wearable Haptic Devices in Rehabilitation of Children With Neuromotor Impairments
Status: COMPLETED
Conditions: Cerebral Palsy|Dyspraxia
Interventions: DEVICE: Serious Game|OTHER: Conventional Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Abraxane and Avastin as Therapy for Patients With Malignant Melanoma, a Phase II Study
Status: COMPLETED
Conditions: Metastatic Malignant Melanoma
Interventions: DRUG: Avastin|DRUG: Abraxane
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study of Conversion Surgery After IP Paclitaxel With XELOX Chemotherapy in AGC With Peritoneal Dissemination
Status: UNKNOWN
Conditions: Advanced Gastric Cancer|Peritoneal Carcinomatosis
Interventions: DRUG: 1. Treatment: IP chemotherapy + Systemic chemotherapy|PROCEDURE: 2. Response evaluation after 4 cycles of IP + systemic chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Implementation of a Pictographic Constipation Action Plan for Children With Functional Constipation
Status: COMPLETED
Conditions: Functional Constipation
Interventions: OTHER: Constipation Action Plan|OTHER: Standard of care without constipation action plan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Determine the Efficacy and Safety of a Benzocaine Lozenge for Treatment of Sore Throat.
Status: COMPLETED
Conditions: Sore Throat
Interventions: DRUG: Benzocaine 8 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess S303 RBCs and Evaluate Safety and Efficacy in Patients Requiring Transfusion Support of Acute Anemia
Status: COMPLETED
Conditions: Focus:Use of S303 RBCs in Patients With Acute Anemia
Interventions: BIOLOGICAL: S-303 Red Blood Cells (RBCs) - Test|BIOLOGICAL: Conventional, untreated red blood cells (RBCs) - Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose:
Clinical trial: Comparison of Remimazolam and Propofol on Emergence in Elderly Orthopedic Patients Under General Anesthesia
Status: COMPLETED
Conditions: Hip Fracture
Interventions: DRUG: Remimazolam|DRUG: Flumazenil|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Human CD19 Targeted T Cells Injection(CD19 CAR-T) Therapy for Relapsed and Refractory B-cell Non-Hodgkin's Lymphoma
Status: RECRUITING
Conditions: B-cell Non-Hodgkin's Lymphoma
Interventions: DRUG: Human CD19Targeted T Cells Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Packed Red Blood Cell Transfusion on Eicosanoid Profiles in Plasma of Intensive Care Patients
Status: TERMINATED
Conditions: Anemia|Critical Illness|Lung Transplantation|Open Aortic Surgery
Interventions: DIAGNOSTIC_TEST: Analysis of eicosanoid profile prior to and after PRBC transfusion
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Succinylcholine on Nonintubated Thoracoscopic Surgery
Status: UNKNOWN
Conditions: Tumor of Lung Parenchyma|Complication of Ventilation Therapy|Atelectasis
Interventions: DRUG: Succinylcholine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Quantitative Identification of Implantation Receptivity by Single Cell Transcriptome Analysis
Status: UNKNOWN
Conditions: Endometrial Receptivity Diagnosis
Interventions: PROCEDURE: Endometrial Biopsy and endometrial fluid collection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Non-invasive Auricular Fiber Vagus Nerve Stimulation (afVNS) for Treatment of Autism Spectrum Disorder
Status: NOT_YET_RECRUITING
Conditions: Autism Spectrum Disorder
Interventions: DEVICE: vagus nerve stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: ST250 as a Therapeutic Option for Head & Neck Reconstruction
Status: NOT_YET_RECRUITING
Conditions: Tonsillitis
Interventions: DEVICE: SupraTHEL 250|OTHER: Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Boceprevir Drug Combination for Hepatitis C Treatment in People With and Without HIV
Status: TERMINATED
Conditions: Hepatitis|HIV/AIDS
Interventions: DRUG: Boceprevir|DRUG: Peg-Interferon-alfa 2B|DRUG: Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Xenical in Children and Adolescents With Obesity-Related Diseases
Status: COMPLETED
Conditions: Diabetes Mellitus|Hypertension|Metabolic Disease|Obesity|Sleep Apnea Syndrome
Interventions: DRUG: Orlistat|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: "The Effect of Comprehensive Non-pharmacological Treatment on Metabolic Disorders in Type 2 Diabetic Patients"
Status: UNKNOWN
Conditions: Type 2 Diabetes
Interventions: COMBINATION_PRODUCT: Comprehensive Non-pharmacological Treatment Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT