pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Study Comparing the Health Effects of Two Diets Following UK Dietary Guidance in People Living With Overweight or Obesity
Status: ACTIVE_NOT_RECRUITING
Conditions: Obesity|Cardiometabolic Syndrome|Overweight
Interventions: DIETARY_SUPPLEMENT: Healthy, balanced Diet A|DIETARY_SUPPLEMENT: Healthy, balanced Diet B|BEHAVIORAL: Behavioural support intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Autologous Bone Marrow Transplantation (BMT) Compared With Allogeneic BMT in Multiple Myeloma
Status: UNKNOWN
Conditions: Multiple Myeloma
Interventions: PROCEDURE: Autologous bone marrow transplantation|PROCEDURE: Allogeneic bone marrow transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Targeted Therapy Using Transcription Activator-like Effector Nucleases in Cervical Precancerous Lesions
Status: UNKNOWN
Conditions: Human Papillomavirus-Related Malignant Neoplasm
Interventions: BIOLOGICAL: T512
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Performance and Stress During Full Scale Simulator Training
Status: COMPLETED
Conditions: Performance in Simulated Emergencies|Stress During Simulator Scenario|Behaviour of Physicians in Simulated Emergencies
Interventions: OTHER: Medical simulator training|OTHER: Simulator based crew resource management course
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: A Prospective Randomized Trial Using Roentgen Stereophotogrammetric Analysis of the Advance Medial Pivot Knee
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: DEVICE: Advance Medial Pivot Knee Arthroplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Assess Efficacy and Safety of the Human Anti-CD38 Antibody Felzartamab (MOR202) in IgA Nephropathy
Status: COMPLETED
Conditions: Immunoglobulin A (IgA) Nephropathy
Interventions: DRUG: Felzartamab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Multi-Dose Study With a Treatment for Open-Angle Glaucoma
Status: WITHDRAWN
Conditions: Open-Angle Glaucoma
Interventions: DRUG: Anecortave Acetate|DRUG: Anecortave Acetate|DRUG: Anecortave Acetate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Extension Study on the Safety and Efficacy of Enteric-coated Mycophenolate Sodium in Kidney Transplant Recipients
Status: COMPLETED
Conditions: Renal Transplantation
Interventions: DRUG: Enteric-Coated Mycophenolate Sodium (EC-MPS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Hydroxyzine Dihydrochloride Premedication is a Necessity for Strabismus Surgery
Status: COMPLETED
Conditions: Strabismus|Reflex, Oculocardiac|Hydroxyzine|Bradycardia Sinus
Interventions: DRUG: Midazolam|DRUG: Hydroxyzine Dihydrochloride
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Efficacy of Anti-CD47, ALX148 in Combination With Liposomal Doxorubicin and Pembrolizumab in Recurrent Platinum-resistant Ovarian Cancer
Status: RECRUITING
Conditions: Ovarian Cancer
Interventions: DRUG: Pembrolizumab|DRUG: ALX148|DRUG: Doxorubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: IVIG Versus Placebo for the Treatment of Patients With Severe C-Diff
Status: TERMINATED
Conditions: Clostridium Difficile-associated Diarrhea (CDAD)
Interventions: DRUG: intravenous immunoglobulin G (IVIG)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Pharmacokinetics and Metabolism of [14C] CR845 (Difelikefalin) in Patients With End Stage Renal Disease on Hemodialysis and in Healthy Subjects
Status: COMPLETED
Conditions: Hemodialysis|Healthy
Interventions: DRUG: [14C] CR845
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Evaluation of Effects of Multiple Dose Regimens of CHF 5074 on Potential Biomarkers of Neurodegeneration in Subjects With Mild Cognitive Impairment
Status: WITHDRAWN
Conditions: Alzheimer's Disease
Interventions: DRUG: CHF 5074 1x|DRUG: CHF 5074 2x|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: BE Study of the Combinations of Gemigliptin 50mg and Rosuvastatin 20mg in Comparison to Each Component Administered Alone
Status: UNKNOWN
Conditions: Healthy
Interventions: DRUG: gemigliptin 50mg, rosuvastatin 20mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Spanish Registry of RYR1 and CACNA1S Polymorphisms
Status: UNKNOWN
Conditions: Malignant Hyperthermia|Polymorphisms in Genes RYR1 and CACNAS1S
Interventions: DIAGNOSTIC_TEST: Diagnostic of polymorphisms in malignant hyperthermia
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase I/II Trial of VB-111 and Paclitaxel for Recurrent Platinum-Resistant Müllerian Cancer
Status: COMPLETED
Conditions: Platinum Resistant Ovarian Cancer
Interventions: DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Opioid Free Anesthesia in Obese Patients.
Status: COMPLETED
Conditions: Opioid Free Anesthesia
Interventions: DRUG: dexmedetomidine,ketamine,lidocaine,propofol|DRUG: fentanyl,propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: An Individualized Internet-Based Health Behavior Program or a Standard Internet-Based Health Behavior Program in Preventing Cancer and Improving Physical Activity and Nutrition in Participants Who Are Physically Inactive With a Higher Body Mass Index
Status: COMPLETED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: BEHAVIORAL: behavioral dietary intervention|OTHER: educational intervention|OTHER: internet-based intervention|OTHER: preventative dietary intervention|PROCEDURE: evaluation of cancer risk factors
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: PREVENTION
Clinical trial: Effect Of A Locally Delivered Probiotic Sacchraomyces Boulardii In The Management Of Chronic Periodontitis
Status: COMPLETED
Conditions: Chronic Periodontitis
Interventions: DRUG: Saccharomyces Boulardii 250 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Stress Testing Compared to Coronary Computed Tomographic Angiography in Patients With Suspected Coronary Artery Disease
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: OTHER: Coronary CTA|OTHER: Stress MPI SPECT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of LY3127760 in Healthy Participants
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: LY3127760|DRUG: Celecoxib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: FFNP-PET/MR Imaging of Progesterone Receptor Expression in Invasive Breast Cancer
Status: SUSPENDED
Conditions: Invasive Breast Cancer
Interventions: DRUG: [18F]Fluorofuranylnorprogesterone (FFNP) PET/MR Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: CBT for Comorbid Anxiety Disorders in Children With Autism, Asperger Syndrome, or PDD-NOS
Status: COMPLETED
Conditions: Autistic Disorder|Asperger Syndrome|Anxiety Disorders
Interventions: BEHAVIORAL: Cognitive-behavioral therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acute Effects of a Botanical Extract and Its Main Volatile Compound on Stress Response in Healthy Adults
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Botanical extract|DIETARY_SUPPLEMENT: Main compound of the botanical extract|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Low Dose Sirolimus or CsA-Based Maintenance Immunosuppression After Induction With Campath-1 in Kidney Transplantation
Status: COMPLETED
Conditions: Kidney Transplant
Interventions: DRUG: Campath-1H
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Advanced Bulky Malignancies With Spatially Fractioned Radiation Therapy
Status: TERMINATED
Conditions: Advanced Bulky Malignancies
Interventions: RADIATION: Spatially Fractioned Radiation Therapy|RADIATION: Treatment Group 1|RADIATION: Standard radiation|RADIATION: Standard radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study to Compare Ibuprofen/ Paracetamol Tablets (200mg Ibuprofen/ 500mg Paracetamol) Versus Nuromol® Tablets (200mg Ibuprofen/ 500mg Paracetamol)
Status: COMPLETED
Conditions: Migraine|Headache|Backache
Interventions: DRUG: Ibuprofen/ Paracetamol tablets|DRUG: Nuromol® tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Comparison of the Quality of Vision Provided by AMO Tecnis Z9000 and Alcon Laboratories MA60 Acrysof Posterior Chamber Intraocular Lenses
Status: COMPLETED
Conditions: Cataract
Interventions: DEVICE: Tecnis Z9000 intraocular lens|DEVICE: MA60 intraocular lens
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Diffusion MRI (Magnetic Resonance Imaging) Using ADC (Apparent Diffusion Coefficient) Histograms in the Evaluation of Adnexal Tumor Aggressiveness
Status: COMPLETED
Conditions: Adnexal Tumor
Interventions: OTHER: Correlation of MRI results with clinical characteristics of the adnexal mass
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: 4D-150 in Patients With Neovascular (Wet) Age-Related Macular Degeneration
Status: RECRUITING
Conditions: Neovascular (Wet) Age-Related Macular Degeneration
Interventions: BIOLOGICAL: 4D-150 IVT|BIOLOGICAL: Aflibercept IVT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ciclosporin Followed by Low-dose IL-2 in Patients With Recently Diagnosed Type 1 Diabetes
Status: RECRUITING
Conditions: Type 1 Diabetes
Interventions: DRUG: Cyclosporin|DRUG: ILT101|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Procalcitonin Level in Normal Population and in Chronic Kidney Disease Patients Who Don't Have Infection
Status: NOT_YET_RECRUITING
Conditions: Chronic Kidney Disease Patients Who Don't Have Infection
Interventions: DIAGNOSTIC_TEST: procalcitonin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Dupilumab-PEdiatric Skin Barrier Function and LIpidomics STudy in Patients With Atopic Dermatitis
Status: COMPLETED
Conditions: Dermatitis Atopic
Interventions: DRUG: Dupilumab SAR231893
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bone Mineral Changes Around Stemless and Stemmed Cementless Femoral Components
Status: COMPLETED
Conditions: Osteoarthritis of Hip
Interventions: DEVICE: Stemless femoral component|DEVICE: IPS, Depuy cementless femoral stem
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lenalidomide Intensification in Patients With Serologic/Asymptomatic Progression of Multiple Myeloma While on Lenalidomide Maintenance
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pulmonary Artery DenerVation Clinical Study Using the Gradient Denervation System in Heart Failure Patients With Pulmonary Hypertension Group 2 (PreVail-PH2 OUS Study)
Status: RECRUITING
Conditions: Pulmonary Hypertension
Interventions: DEVICE: Gradient Denervation System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Umbrella Review of the DASH Dietary Pattern and Cardiometabolic Risk
Status: UNKNOWN
Conditions: Cardiovascular Risk Factor|Cardiovascular Diseases|Coronary Heart Disease|Stroke|Diabetes|Blood Pressure|Cholesterol; Lipidosis|Inflammation|Adiposity
Interventions: OTHER: DASH dietary pattern
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Compare Pharmacokinetic(PK) Profiles of XZK vs Lovastatin in Healthy Male Volunteers
Status: COMPLETED
Conditions: Lipid Metabolism Disorder
Interventions: DRUG: XueZhiKang|DRUG: Lovastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Novel Flash Glucose Monitoring System on Glycemic Control in Adult Patients With Type 1 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: DEVICE: Flash glucose monitoring system|DEVICE: SMBG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Vildagliptin Versus Dapagliflozin on Glucagon
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: Vildagliptin|DRUG: Dapagliflozin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Prescription Patterns, Resource Utilization & Costs - Add-on Therapy With Anti Dipeptidyl Peptidase-IVs vs Rosiglitazone
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Rosiglitazone + Metformin|DRUG: Sitagliptin + Metformin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pioglitazone Hydrochloride in Preventing Radiation-Induced Cognitive Dysfunction in Treating Patients With Brain Tumors
Status: COMPLETED
Conditions: Brain Neoplasms, Malignant|Brain Neoplasms, Benign|Malignant Meningioma|Glioblastoma Multiforme|Anaplastic Astrocytoma
Interventions: DRUG: pioglitazone|DRUG: Pioglitazone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: An Adaptive Algorithm-Based Approach to Treatment for Adolescent Depression
Status: COMPLETED
Conditions: Depressive Disorder
Interventions: BEHAVIORAL: Interpersonal Psychotherapy for Depressed Adolescents|DRUG: Selective Serotonin Reuptake Inhibitor|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fludarabine, Rituximab, and Alemtuzumab in Treating Patients With Chronic Lymphocytic Leukemia
Status: COMPLETED
Conditions: B-cell Chronic Lymphocytic Leukemia|Stage I Chronic Lymphocytic Leukemia|Stage II Chronic Lymphocytic Leukemia|Stage III Chronic Lymphocytic Leukemia|Stage IV Chronic Lymphocytic Leukemia
Interventions: BIOLOGICAL: alemtuzumab|BIOLOGICAL: rituximab|DRUG: fludarabine phosphate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Alveolar Cleft Reconstruction Using Bone Marrow Aspirate Concentrate and Allograft vs Iliac Cancellous Bone.
Status: NOT_YET_RECRUITING
Conditions: Alveolar Cleft Grafting
Interventions: PROCEDURE: BMAC MIXED WITH ALLOGRAFT|PROCEDURE: Cancellous bone from anterior iliac crest
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect Study of on Intervention on Pain, Function, Health and Behaviour for Older Adults Living With Chronic Pain
Status: UNKNOWN
Conditions: Chronic Pain
Interventions: BEHAVIORAL: Individual tailored functional exercise|BEHAVIORAL: Standard care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study of Sitravatinib With or Without Other Anticancer Therapies Receiving Clinical Benefit From Parent Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced or Metastatic Solid Malignancies
Interventions: DRUG: Sitravatinib|DRUG: Nivolumab|DRUG: Pembrolizumab|DRUG: Enfortumab Vedotin-Ejfv|DRUG: Ipilimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Pembrolizumab (MK-3475) in Participants With Advanced Non-small Cell Lung Cancer (MK-3475-025/KEYNOTE-025)
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer
Interventions: BIOLOGICAL: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of MGC026 in Participants With Advanced Solid Tumors
Status: RECRUITING
Conditions: Advanced Solid Tumor|Advanced Cancer|Metastatic Cancer|Squamous Cell Carcinoma of Head and Neck|Non Small Cell Lung Cancer|Small-cell Lung Cancer|Bladder Cancer|Sarcoma|Endometrial Cancer|Melanoma|Castration Resistant Prostatic Cancer|Cervical Cancer|Colorectal Cancer|Gastric Cancer|Gastro-esophageal Cancer|Pancreas Cancer|Clear Cell Renal Cell Carcinoma|Hepatocellular Carcinoma|Platinum-resistant Ovarian Cancer
Interventions: BIOLOGICAL: MGC026 Dose Escalation|BIOLOGICAL: MGC026 Dose for Expansion
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Immunogenicity and Reactogenicity of Various Formulations of Recombinant Hepatitis B Vaccine
Status: COMPLETED
Conditions: Hepatitis B
Interventions: BIOLOGICAL: HBsAg formulated with different concentrations of MPL and Aluminium Salts|BIOLOGICAL: Engerix™-B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Impact of SARS-CoV-2 (COVID-19) Infection, Treated in Ambulatory Care, on Long-term Quality of Life in a Parisian Military Population
Status: COMPLETED
Conditions: SARS-CoV2 Infection|Covid19
Interventions: OTHER: Questionnaires COVID+|OTHER: Questionnaires COVID-
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: "Mindfulness vs Psychoeducation in Bipolar Disorder"
Status: UNKNOWN
Conditions: Bipolar|Depressive Symptoms
Interventions: BEHAVIORAL: Mindfulness Based Cognitive Therapy (MBCT)|BEHAVIORAL: Psychoeducation|BEHAVIORAL: Standard treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An International Clinical Program for the Diagnosis and Treatment of Children With Ependymoma
Status: RECRUITING
Conditions: Childhood Ependymoma
Interventions: DRUG: 16 weeks of VEC + CDDP|DRUG: VEC + HD-MTX|DRUG: Chemotherapy + Valproate|RADIATION: Conformal radiotherapy|DRUG: VEC|DRUG: Chemotherapy|RADIATION: conformal radiotherapy +/- boost
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nano-Pulse Stimulation (NPS) in Sebaceous Hyperplasia
Status: COMPLETED
Conditions: Skin Lesion|Skin Abnormalities|Sebaceous Hyperplasia
Interventions: DEVICE: Nano-Pulse Stimulation Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: DWI Offenders and Their Families App for Smartphones
Status: COMPLETED
Conditions: Coping Skills|Family Relations
Interventions: BEHAVIORAL: B-SMART Intervention Group|BEHAVIORAL: Usual and Customary Information Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety Demonstration of Increasing Intensities of Electrical Stimulation Delivered to The Bulbospongiosus Muscle
Status: COMPLETED
Conditions: Premature Ejaculation
Interventions: DEVICE: TENS Stimulator
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: An Open-label Study to Assess the Long-term Safety, Tolerability, Effectiveness, and Durability of Effect of KarXT in Patients With DSM-5 Diagnosis of Schizophrenia
Status: TERMINATED
Conditions: Schizophrenia
Interventions: DRUG: Xanomeline and Trospium Chloride Capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Taxi ROADmAP (Realizing Optimization Around Diet And Physical Activity)
Status: RECRUITING
Conditions: Overweight|Overweight and Obesity|Overweight or Obesity|Obesity|Obese
Interventions: BEHAVIORAL: Counseling|BEHAVIORAL: Text Messages|BEHAVIORAL: Phone calls|BEHAVIORAL: Self-monitoring tools
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Long-Term Effects of Infliximab in the Treatment of Moderate to Severe Psoriasis [Extension of Study P04271, NCT00251641] (P04563)
Status: TERMINATED
Conditions: Psoriasis
Interventions: BIOLOGICAL: infliximab|BIOLOGICAL: infliximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: China Diabetes Registry by Metabolic Management Center
Status: RECRUITING
Conditions: Type 2 Diabetes Mellitus|Type1 Diabetes Mellitus|Monogenetic Diabetes|Pancreatogenic Diabetes|Drug-Induced Diabetes Mellitus|Other Forms of Diabetes Mellitus
Interventions: OTHER: Standard diabetes management model in each MMC center
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Random Nicotine Delivery on Smoking Cessation
Status: COMPLETED
Conditions: Smoking Cessation|Cigarette Smoking|Smoking (Tobacco) Addiction
Interventions: DRUG: Nicotine Film
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tissue Procurement and Natural History Study of People With Non-Small Cell Lung Cancer, Small Cell Lung Cancer, Extrapulmonary Small Cell Cancer, Pulmonary Neuroendocrine Tumors, and Thymic Epithelial Tumors
Status: RECRUITING
Conditions: Non-Small Cell Lung Cancer|Small Cell Lung Cancer|Extrapulmonary Small Cell Cancer|Pulmonary Neuroendocrine Tumors|Thymic Epithelial Tumors
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Losartan Therapy in Pulmonary Hypertension
Status: COMPLETED
Conditions: Pulmonary Hypertension
Interventions: DRUG: nifedipine, losartan|DRUG: losartan|DRUG: Nifedipine, losartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Zonisamide for Heavy Drinkers With Bipolar Disorder
Status: TERMINATED
Conditions: Alcohol Use Disorders|Bipolar Disorder
Interventions: DRUG: Zonisamide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Safety and Efficacy Trial of Dapivirine Vaginal Ring in Africa
Status: WITHDRAWN
Conditions: HIV Infections
Interventions: OTHER: Dapivirine|OTHER: Placebo|DRUG: Dapivirine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of the Safety of Risperidone in the Treatment of Children and Adolescents With Conduct and Other Disruptive Behavior Disorders
Status: COMPLETED
Conditions: Disruptive Behavior Disorder
Interventions: DRUG: risperidone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sysmex-XN 20 Analyser to Assess Lymphocyte Subsets and Other Haematological Parameters in Chronic/Acute Viral Infections
Status: UNKNOWN
Conditions: Diagnostic|Chronic Viral Hepatitis B|Chronic Hepatitis C|Chronic HIV Infection
Interventions: DIAGNOSTIC_TEST: blood draw
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study Evaluating SKI-606 (Bosutinib) In Japanese Subjects With Philadelphia Chromosome Positive Leukemias
Status: COMPLETED
Conditions: Chronic Myelogenous Leukemia
Interventions: DRUG: SKI-606 (Bosutinib)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Drug-drug Interaction Between LCZ696 and Sildenafil in Subjects With Mild to Moderate Hypertension
Status: COMPLETED
Conditions: Mild to Moderate Hypertension
Interventions: DRUG: LCZ696|DRUG: Sildenafil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: A Clinical Study to Evaluate Efficacy and Safety of a Cosmetic Product in the Treatment of Facial Lines
Status: COMPLETED
Conditions: Fine Lines|Wrinkles|Photoaging
Interventions: COMBINATION_PRODUCT: Facial cleanser|COMBINATION_PRODUCT: Facial moisturizer|COMBINATION_PRODUCT: Sunscreen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Extended-Release Naltrexone and Monthly Extended-Release Buprenorphine for Cocaine Use Disorder (CURB-2)
Status: RECRUITING
Conditions: Cocaine Use Disorder
Interventions: DRUG: Extended-Release Naltrexone|DRUG: Extended Release Buprenorphine|DRUG: Placebo (PLB) Injectable matched to XR-NTX|DRUG: Placebo (PLB) Injectable matched to XR-BUP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Controlled Trial of Milk Products and Physical Activity on Body Composition and Health in Overweight Young Males
Status: UNKNOWN
Conditions: Overweight
Interventions: OTHER: Increased Dairy Intake|OTHER: Supplemental carbohydrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Real-world Study of Lamivudine and Dotiravir Sodium Tablets in the Treatment-naïve HIV-1 Infected Patients
Status: NOT_YET_RECRUITING
Conditions: HIV-1-infection
Interventions: DRUG: Lamivudine and Dotiravir Sodium Tablets
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: WorkWell: Work-based Activity and Metabolic Health
Status: COMPLETED
Conditions: PreDiabetes|Obesity
Interventions: BEHAVIORAL: Standing condition|BEHAVIORAL: Light physical activity (LPA) condition|BEHAVIORAL: Usual behavior condition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Efficiency of Virtual Reality Exposure Therapy in the Management of Body Dysmorphic Disorders in Female Adolescents With Anorexia Nervosa
Status: RECRUITING
Conditions: Anorexia Nervosa
Interventions: BEHAVIORAL: Virtual Reality Exposure Therapy sessions|BEHAVIORAL: Psychomotor therapy sessions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 First-In-Human Study of the Anti-CD73 IPH5301 Alone or in Combination With Chemotherapy and Trastuzumab in Patients With Advanced Solid Tumors
Status: RECRUITING
Conditions: Metastatic Cancer|Metastatic Breast Cancer|Metastatic Pancreatic Cancer|Metastatic Gastric Cancer|Metastatic Lung Cancer|Metastatic Ovary Cancer|Oesophageal Cancer|Endometrial Cancer|Advanced Solid Tumor
Interventions: DRUG: IPH5301 ALONE OR IN COMBINATION WITH CHEMOTHERAPY AND TRASTUZUMAB
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of 2 Initial Standard Antiretroviral Combinations Therapies on Lipid Metabolism
Status: UNKNOWN
Conditions: HIV Infections
Interventions: DRUG: Tenofovir + emtricitabine + efavirenz|DRUG: Tenofovir + emtricitabine + lopinavir/ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BCG Vaccination Delivered Intradermally, Orally and by Combined Routes
Status: COMPLETED
Conditions: Tuberculosis
Interventions: BIOLOGICAL: BCG strain Connaught|BIOLOGICAL: BCG strain Danish|BIOLOGICAL: BCG strain Danish|OTHER: Placebo|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study to Evaluate Efficacy and Safety of BGB-3111 in Participants With Relapsed or Refractory Mantle Cell Lymphoma (MCL)
Status: COMPLETED
Conditions: Refractory Mantle Cell Lymphoma|Relapsed Mantle Cell Lymphoma
Interventions: DRUG: Zanubrutinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impedance Cardiography to Decrease the Risk of Preeclampsia
Status: WITHDRAWN
Conditions: Chronic Hypertension Complicating Pregnancy (Diagnosis)|Preeclampsia
Interventions: DRUG: Labetalol Hydrocholoride 200 mg orally every 12 hours|DRUG: Nifedipine 60 mg orally daily|DRUG: Atenolol 25 mg daily
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Email Nudges to Improve GDMT (MRA) Adherence in Heart Failure
Status: WITHDRAWN
Conditions: Heart Failure With Reduced Ejection Fraction
Interventions: OTHER: Email Nudge
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Safety and Efficacy of SCH 503034 in Previously Untreated Subjects With Chronic Hepatitis C Infected With Genotype 1 (Study P03523)
Status: COMPLETED
Conditions: Chronic Hepatitis C
Interventions: DRUG: boceprevir (SCH 503034)|DRUG: peginterferon-alfa 2b (PegIntron)|DRUG: ribavirin|DRUG: ribavirin (low-dose)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Individualizing Treatment for Asthma in Primary Care
Status: RECRUITING
Conditions: Asthma|Bronchial Diseases|Respiratory Tract Infections|Lung Diseases, Obstructive|Lung Diseases|Respiratory Hypersensitivity|Immune System Diseases
Interventions: OTHER: Asthma Symptom Monitoring online tools|DRUG: Inhaled Steroids|DRUG: Azithromycin Pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Safe Access for Bladder Entry in Transgender Men Following Penile Reconstruction
Status: COMPLETED
Conditions: Transgenderism|Catheter Related Complication
Interventions: DEVICE: Urethrotech Urethral catheterisation device (UCD)|DEVICE: Bardia Aquafil long term catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Vonoprazan-based Versus Lansoprazole-based Triple Therapy, High Dose Dual Therapy, Bismuth and Non-bismuth Quadruple Therapy in the First-line Treatment of Helicobacter Pylori Infection
Status: RECRUITING
Conditions: H. Pylori Infection
Interventions: DRUG: (A) T-V14|DRUG: (B) T-V7|DRUG: (C) D-V14|DRUG: (D) HD-V14|DRUG: (E) BQ-V14|DRUG: (F) RH-V14|DRUG: (G) BQ-L14|DRUG: (H) T-L14
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of a Mechanical Chair for Treatment of Benign Paroxysmal Positional Vertigo (BPPV)
Status: TERMINATED
Conditions: Vertigo|Benign Paroxysmal Positional Vertigo
Interventions: OTHER: Standard Repositioning|OTHER: Mechanical Chair Repositioning|OTHER: Sham Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Molecularly Tailored Therapy to Standard of Care as Second-Line Therapy in Metastatic Pancreatic Cancer
Status: WITHDRAWN
Conditions: Metastatic Pancreatic Cancer
Interventions: OTHER: Molecularly Tailored Second Line Therapy|DRUG: Standard of Care Second Line Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of a Combination of Polyphenol-rich Extracts on the Protection of Retinal Cells Against Blue Light in the Prevention of Ocular Diseases
Status: COMPLETED
Conditions: Eye Abnormalities
Interventions: DIETARY_SUPPLEMENT: Complex product|DIETARY_SUPPLEMENT: Polyphenol-rich extracts|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Transatrial Pericardial Separation to Enhance Safety of Subxiphoid Pericardial Access for Left Atrial Appendage Ligation
Status: COMPLETED
Conditions: Atrial Fibrillation|Left Atrial Appendage Ligation|Pericardium|Epicardial Mapping|Heart Atria|Cardiac Surgical Procedures|Cardiac Catheterization|Pneumopericardium|Left Atrial Appendage Occlusion
Interventions: PROCEDURE: Pericardial insufflation with carbon dioxide through a transatrial microcatheter
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Information, Networks and Rewards to Optimise Adherence to Diabetic Services
Status: COMPLETED
Conditions: Diabetes
Interventions: BEHAVIORAL: cash rewards for the fellow up|BEHAVIORAL: Showing retinal photos to participants|BEHAVIORAL: SMS reminders for participants and their family|BEHAVIORAL: Watching brief video and basic explanation for disease|BEHAVIORAL: Having the Diabetic Club
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Camrelizumab Plus Apatinib and Temozolomide as First Line Therapy in Advanced Acral Melanoma
Status: UNKNOWN
Conditions: Melanoma
Interventions: DRUG: SHR1210|DRUG: apatinib mesylate|DRUG: Temozolomide Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Oral Methylnaltrexone (MNTX) for the Treatment of Opioid-Induced Constipation (OIC) in Participants With Chronic, Non-Malignant Pain
Status: COMPLETED
Conditions: Opioid-Induced Constipation
Interventions: DRUG: Methylnaltrexone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Surgery Versus Radiosurgery for the Treatment of Single Brain Metastases
Status: WITHDRAWN
Conditions: Patients With a Single Brain Metastasis
Interventions: PROCEDURE: Surgery|PROCEDURE: Stereotactic Radiosurgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Pilot Study Assessing Efficacy of a Cisplatin - Metronomic Cyclophosphamide Treatment in Patients With Metastatic Triple Negative Breast Cancer Resistant to Anthracyclines and Taxanes
Status: TERMINATED
Conditions: Metastatic Breast Cancer
Interventions: DRUG: Cisplatin|DRUG: Metronomic Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Aerosolized Drugs Deposition During Mechanical Ventilation
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Salbutamol|DRUG: Acetylcysteine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Long-Term Effectiveness of Walking Training in Patients With Knee Osteoarthritis
Status: TERMINATED
Conditions: Osteoarthritis
Interventions: OTHER: Gait Training; Altered Foot Progression Angle|OTHER: Gait Training; Consistent Foot Progression Angle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Evaluate the Efficacy and Safety of EsoDuo Tab. 20/800mg
Status: COMPLETED
Conditions: Non-erosive Reflux Disease(NERD)
Interventions: DRUG: EsoDuo Tab. 20/800mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Medium Chain Triglyceride Intake on Colonization of Preterm Infants With Candida
Status: COMPLETED
Conditions: Candida Infection|Premature Infant
Interventions: DRUG: Medium-Chain Triglyceride (MCT) Oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Description of Pneumococcal Pneumonia
Status: COMPLETED
Conditions: Community-acquired Pneumonia
Interventions: OTHER: Signs of CAP and a positive chest X-Ray|OTHER: Patients directly hospitalized|DIAGNOSTIC_TEST: Control patients|OTHER: Patients with partial participation|OTHER: Signs of CAP and a negative chest X-Ray
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Natural History Study for DNA Repair Disorders
Status: RECRUITING
Conditions: DNA Repair Disorder|Cockayne Syndrome|Xeroderma Pigmentosum|Trichothiodystrophy
Interventions: OTHER: Interval History|OTHER: Physical Examination|OTHER: ECAB Assessment|OTHER: Gait Assessment|OTHER: Specimen Sample Collection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Global Phase 3 Study to Evaluate the Safety and Efficacy of Elagolix in Subjects With Moderate to Severe Endometriosis-Associated Pain
Status: COMPLETED
Conditions: Endometriosis
Interventions: OTHER: placebo|DRUG: Elagolix
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Concurrent Proton and Chemotherapy in Locally Advanced Stage IIIA/B Non-Small Cell Lung Cancer (NSCLC)
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DRUG: Carboplatin|RADIATION: Proton Radiotherapy|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: the Effect of Diane-35 Pretreatment on In-vitro Fertilization Outcome for Patients With Polycystic Ovary Syndrome
Status: UNKNOWN
Conditions: Polycystic Ovary Syndrome
Interventions: DRUG: Diane-35 pretreatment|DRUG: Diane-35 pretreatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose-Dense Epirubicin and Cyclophosphamide (EC) Followed by Paclitaxel in Breast Cancer: Feasibility
Status: COMPLETED
Conditions: Breast Cancer|Adenocarcinoma of the Breast
Interventions: DRUG: epirubicin, cyclophosphamide, Paclitaxel,
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trials of Quick-Acting Heart Reliever for Moderate Coronary Stenosis
Status: COMPLETED
Conditions: Coronary Artery Stenosis|Coronary Heart Disease
Interventions: DRUG: Quick-Acting Heart Reliever|DRUG: Isosorbide Dinitrate|DRUG: Placebo of Isosorbide Dinitrate|DRUG: Aspirin Enteric-coated Tablets|DRUG: Placebo of Quick-Acting Heart Reliever|DRUG: Aspirin Enteric-coated Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of NRX 195183 Therapy for Patients With Relapsed or Refractory Acute Promyelocytic Leukemia
Status: UNKNOWN
Conditions: Acute Promyelocytic Leukemia
Interventions: DRUG: NRX 195183 Soft Gelatin Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Effectiveness of(VistaProof)in Comparison With ICDAS-II & Histological Validation for Detecting Occlusal Caries
Status: COMPLETED
Conditions: Light Fluorescence Device
Interventions: DEVICE: vistacam proof|OTHER: ICDASII|PROCEDURE: fissurotomy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Experimentation of an Ankle Mobilization Device for the Rehabilitation of Patients With Acquired Brain Injuries.
Status: COMPLETED
Conditions: Acquired Brain Injury
Interventions: DEVICE: Ankle active and passive mobilization using an Ankle mobilization device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Development of a Telehealth-delivered Peer Navigation and Coping Skills Intervention to Increase PrEP Use in Young Black MSM
Status: TERMINATED
Conditions: Hiv|Sexual Behavior
Interventions: BEHAVIORAL: Peer Navigation and Coping Skills|BEHAVIORAL: Treatment as Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Mechanistic Assessment of the Properties of Saxagliptin in Subjects Undergoing Coronary Artery Bypass Graft Surgery
Status: TERMINATED
Conditions: Type 2 Diabetes Mellitus|Cardiovascular Disease
Interventions: DRUG: Saxagliptin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose:
Clinical trial: Evaluation of Efficacy of Levamisole and Formoterol+Budesonide in Treatment of COVID-19
Status: UNKNOWN
Conditions: COVID-19
Interventions: DRUG: Levamisole Pill + Budesonide+Formoterol inhaler|DRUG: Lopinavir/Ritonavir + hydoxychloroquine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Beta-Hydroxy-Beta-Methylbutyrate Supplementation and Physical Activity in Liver Cirrhosis: a Controlled Trial
Status: UNKNOWN
Conditions: Sarcopenia|Cirrhosis, Liver
Interventions: DIETARY_SUPPLEMENT: BETA-HYDROXY-BETA-METHYLBUTYRATE (HMB)|DIETARY_SUPPLEMENT: Mannitol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ponatinib in Participants With Resistant Chronic Phase Chronic Myeloid Leukemia (CP-CML) to Characterize the Efficacy and Safety of a Range of Doses
Status: ACTIVE_NOT_RECRUITING
Conditions: Myeloid Leukemia, Chronic, Chronic Phase
Interventions: DRUG: Ponatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Dose-Ranging Study of ATI 7505 in Patients With Postprandial Distress Syndrome
Status: TERMINATED
Conditions: Post Prandial Distress Syndrome
Interventions: DRUG: Placebo|DRUG: 20 mg ATI 7505|DRUG: 40 mg ATI 7505|DRUG: 80 mg ATI 7505
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Fusion Rates of 3D Printed Porous Titanium Cages in Three and Four Level ACDFs
Status: ACTIVE_NOT_RECRUITING
Conditions: Radiculopathy|Myelopathy Cervical|Foraminal Stenosis|Central Canal Stenosis
Interventions: DEVICE: DePuy Synthes Conduit 3D printed titanium cages
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: An Exploratory Clinical Trial to Evaluate the Efficacy and Safety of a Novel Antibacterial Bone Traction Needle
Status: RECRUITING
Conditions: Wound Infection
Interventions: DEVICE: antibacterial bone traction needles
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Curcumin Associated With Thiopurin in the Prevention of Post-op Recurrence in Crohn Disease
Status: COMPLETED
Conditions: Crohn's Disease
Interventions: DRUG: Curcumin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT