pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: The Efficacy and Safety of Early MSAT on Radiating Pain in the Upper Extremity
Status: RECRUITING
Conditions: Radiating Pain in the Upper Extremity
Interventions: PROCEDURE: Cervical motion style acupuncture treatment(Trapezius, Rhomboid, Scalene)|PROCEDURE: Korean medical treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MBCT Via Group Videoconferencing for Acute Coronary Syndrome Patients With Depressive Symptoms: A Pilot RCT
Status: ACTIVE_NOT_RECRUITING
Conditions: Cardiovascular Diseases|Acute Coronary Syndrome|Depression
Interventions: BEHAVIORAL: Adapted MBCT|BEHAVIORAL: Cardiac Health Enhancement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics, Safety and Efficacy Study of GP30341 (GEROPHARM, Russia)
Status: COMPLETED
Conditions: Pharmacokinetics|Safety Issues|Efficacy
Interventions: DRUG: GP30341 capsules 200 mg|DRUG: Standard therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Guayusa Extract on Exercise Training
Status: COMPLETED
Conditions: Desire to Exercise|Exercise Training|Physical Exertion
Interventions: DIETARY_SUPPLEMENT: Organic Guayusa Extract|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Renal Transplants in Hepatitis C Negative Recipients With Nucleic Acid Positive Donors
Status: COMPLETED
Conditions: End Stage Renal Disease|Hepatitis C
Interventions: DRUG: 300mg glecaprevir/pibrentasivir 120mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Designing Impactful Warnings for Sugary Drinks
Status: COMPLETED
Conditions: Health Behavior
Interventions: BEHAVIORAL: Text warning with square background|BEHAVIORAL: Text warning with octagon background|BEHAVIORAL: Icon warning|BEHAVIORAL: Graphic warning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Clinical Efficacy, Safety and Tolerability of ARX-F03 Sublingual Sufentanil/Triazolam NanoTab™ in Patients Undergoing an Elective Abdominal Liposuction Procedure
Status: COMPLETED
Conditions: Sedation|Anxiety|Pain
Interventions: DRUG: Sublingual Sufentanil/Triazolam NanoTab™ (ARX-F03)|DRUG: Placebo NanoTab™
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pediatric Femur Fractures: Functional Bracing vs Spica Casting - Outcomes and Cost Analysis
Status: NOT_YET_RECRUITING
Conditions: Pediatric Femur Fracture
Interventions: DEVICE: Functional Bracing|DEVICE: Hip Spica Cast
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Internal Jugular Vein Versus Axillary Vein for Implantable Ports
Status: COMPLETED
Conditions: Catheter Complications|Cancer
Interventions: PROCEDURE: Right internal jugular access.|PROCEDURE: Left internal jugular access.|PROCEDURE: Right axillary vein access.|PROCEDURE: Left axillary vein access.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Side Effects in Hypogonadal Men Treated With Natesto Versus Testosterone Injections
Status: COMPLETED
Conditions: Hypogonadism, Male
Interventions: DRUG: Testosterone Cypionate 200 Mg/ML|DRUG: Intranasal Testosterone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Immunogenicity of GSK Biologicals' Seasonal Influenza Vaccine in Adults
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Fluarix™/Influsplit SSW®
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Role of Glucagon-Like Peptide-1 in Postprandial Hypoglycemia
Status: COMPLETED
Conditions: Postprandial Hypoglycemia
Interventions: DRUG: Exendin-(9-39)|OTHER: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Endomicroscopy and Gastric MALT-lymphoma
Status: COMPLETED
Conditions: MALT-lymphoma
Interventions: PROCEDURE: Confocal laser endomicroscopy|DEVICE: Confocal Laser Endomicroscope
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Digital Therapeutic for Adolescent Depressive Symptoms in Cardiology and Gastroenterology
Status: TERMINATED
Conditions: Depressive Symptoms|Major Depressive Disorder|Depression|Cardiology|Gastrointestinal Diseases|Depressive Disorder|Depressive Episode|Adolescent Behavior|Adolescent - Emotional Problem
Interventions: DEVICE: SparkRx Mobile App
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lidocaine Infusion for Postthoracotomy Pain Syndrome
Status: UNKNOWN
Conditions: Thoracic Surgery, Video-Assisted|Lidocaine|Pain, Postoperative|Chronic Pain
Interventions: DRUG: Lidocaine|DRUG: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Biomarkers in Predicting Response to Chemotherapy in Patients With Advanced or Metastatic Melanoma Previously Treated With Carboplatin and Paclitaxel With or Without Sorafenib Tosylate
Status: COMPLETED
Conditions: Melanoma (Skin)
Interventions: GENETIC: DNA methylation analysis|GENETIC: gene expression analysis|OTHER: laboratory biomarker analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Prevention of Peritonitis in Peritoneal Dialysis
Status: COMPLETED
Conditions: Kidney Failure, Chronic|Peritoneal Dialysis-associated Peritonitis|Dialysis Capd Infection
Interventions: BEHAVIORAL: Follow-up of PD patients´ theoretical and practical skills
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Dynamic Hormone Diagnostics in Endocrine Disease
Status: COMPLETED
Conditions: Adrenal Insufficiency|Congenital Adrenal Hyperplasia|Cushing Syndrome|Growth Hormone Deficiency|Acromegaly|Primary Hyperaldosteronism
Interventions: OTHER: 27 hour subcutaneous fluid sampling
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Clinical Trial to Evaluate the Sensitivity of a Number of Clinical and Psychological Outcome Measures for Cancer Patients Being Treated at the Hospital Day Care Unit or (Partially) at Home
Status: COMPLETED
Conditions: Cancer
Interventions: PROCEDURE: Oncological Home Hospitalization
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Xeltis Hemodialysis Access Graft: aXess Pivotal Study
Status: RECRUITING
Conditions: End-stage Renal Disease
Interventions: DEVICE: Xeltis Hemodialysis Access (aXess) graft
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Uroxatral in Men With Benign Prostate Hypertrophy (BPH) and Erectile Dysfunction (ED)
Status: COMPLETED
Conditions: BPH|Erectile Dysfunction
Interventions: DRUG: Alfuzosin 10 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevalence of ESBL-producing Enterobacteriaceae as Carbapenem-resistant Enterobacteriaceae in Nursing Homes.
Status: COMPLETED
Conditions: Drug Resistance, Bacterial
Interventions: DIAGNOSTIC_TEST: rectal swab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Transcutaneous Posterior Nerve Stimulation inTreatment of Fecal Incontience
Status: COMPLETED
Conditions: Fecal Incontinence
Interventions: DEVICE: Transcutanous Posterior Tibial Nerve Stimulation|DEVICE: Sham Transcutanous Posterior Tibial Nerve Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sirolimus in Conjunction With Eylea vs Eylea Alone for Exudative AMD
Status: COMPLETED
Conditions: Exudative Age Related Macular Degeneration
Interventions: DRUG: Sirolimus|DRUG: EYLEA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Primary Needle Knife Fistulotomy Versus Conventional Cannulation Method
Status: COMPLETED
Conditions: Common Bile Duct Stone|Malignant Hepatobiliary Neoplasm|Biliary Stricture|Pancreatic Diseases|Sphincter of Oddi Dysfunction
Interventions: DEVICE: cannulation of ampulla of Vater
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Combination of Gemcitabine and Imatinib Mesylate in Pemetrexed-pretreated Patients With Pleural Mesothelioma
Status: COMPLETED
Conditions: Mesothelioma, Malignant
Interventions: DRUG: Gemcitabine|DRUG: Imatinib mesylate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of Subcutaneous Sonelokimab Compared With Placebo in Adult Participants With Moderate to Severe Hidradenitis Suppurativa
Status: RECRUITING
Conditions: Hidradenitis Suppurativa
Interventions: DRUG: Sonelokimab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Phase 3 Study of Efficacy and Safety of the XaraColl® Bupivacaine Implant After Hernioplasty
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: DRUG: XaraColl|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Home Use of Transcutaneous Electrical Nerve Stimulation on People With Knee OA and or Chronic Knee Pain
Status: UNKNOWN
Conditions: Knee Pain Chronic|Knee Osteoarthritis
Interventions: DEVICE: Active TENS|DEVICE: Sham TENS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Intervention Based on Implicit Theories of Personality: Effects on Depression and Bullying
Status: COMPLETED
Conditions: Depression|Bullying
Interventions: BEHAVIORAL: Incremental theory of personality|OTHER: Educational Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Educational Intervention to Adherence of Patients Treated by Capecitabine +/- Lapatinib
Status: TERMINATED
Conditions: Metastatic Breast Cancer|Colorectal Cancer
Interventions: OTHER: Educational Intervention to enhance the adherence of Patient treated by capecitabine +/- Lapatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Pregabalin and Etoricoxib on Pain Alone Versus in Combination
Status: NOT_YET_RECRUITING
Conditions: Back Pain Lower Back Chronic
Interventions: DRUG: etoricoxib 60mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Three Methods of Hemoglobin Monitoring in Pediatric Patients Undergoing Major Surgery
Status: COMPLETED
Conditions: Child
Interventions: DEVICE: blood measurement|DEVICE: pulse co-oxymeter (SpHb)|DEVICE: hemoCue
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Intraoperative Lidocaine Infusion for Analgesia (ILIA)
Status: COMPLETED
Conditions: Elective Total or Subtotal Abdominal Hysterectomy
Interventions: DRUG: Lidocaine Intravenous Infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Autologous Hematopoietic Stem Cell Transplantation to Treat New Onset Type 1 Diabetes
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: PROCEDURE: immunosuppression and stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Alpha Lipoic Acid Supplementation on Metabolic Syndrome Markers in Young Overweight or Obese Males
Status: COMPLETED
Conditions: Metabolic Syndrome|Obesity
Interventions: DIETARY_SUPPLEMENT: Alpha Lipoic Acid Supplement|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Dual Growth Factor (rhTPO + G-CSF) and Chemotherapy Combination Regimen for Elderly Patients With Acute Myeloid Leukemia: A Phase II Single-Arm Multicenter Study
Status: RECRUITING
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: rhTPO
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of GTPase Inhibition by Post-operative Intravenous Ketorolac in Ovarian Cancer Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Ovarian Cancer|Fallopian Tube Cancer|Peritoneal Cancer
Interventions: DRUG: Ketorolac|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Dexamethasone Versus Dexmedetomidine as Adjuncts to Serratus Anterior Plane Block
Status: NOT_YET_RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Dexamethasone|DRUG: Dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Cycloserine rTMS Plasticity Augmentation in Depression
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: Cycloserine|DEVICE: Transcranial Magnetic Stimulation|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Development of Upper Extremity Rehabilitation Program Using Virtual Reality for the Stroke Patients
Status: COMPLETED
Conditions: Upper Extremity Dysfunction After the Stroke
Interventions: OTHER: Virtual reality program for upper extremity rehabilitation|OTHER: standard occupational therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: The Effect of the Care Given to Hemodialysis Patients on Comfort Level and Complaints
Status: NOT_YET_RECRUITING
Conditions: Hemodialysis Complication|Nurse's Role
Interventions: OTHER: nursing care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Trial of Cannabidiol to Treat Severe Behavior Problems in Children With Autism
Status: ACTIVE_NOT_RECRUITING
Conditions: Autism|Autism Spectrum Disorder
Interventions: DRUG: Epidiolex|DRUG: placebo oral solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sequential Preoperative Penpulimab Combined With Chemoradiotherapy(CRT) for Locally Advanced Esophageal Squamous Cell Cancer
Status: NOT_YET_RECRUITING
Conditions: Esophageal Squamous Cell Carcinoma
Interventions: DRUG: Penpulimab Combined With CRT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Donor T-lymphocytes Depleted ex Vivo of Host Alloreactive T-cells (ATIR) in Patients With a Hematologic Malignancy Who Received a Hematopoietic Stem Cell Transplantation From a Haploidentical Donor
Status: COMPLETED
Conditions: Acute Myeloid Leukemia|Acute Lymphoblastic Leukemia|Myelodysplastic Syndrome
Interventions: BIOLOGICAL: ATIR
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Anxiety and Depression Levels in Cancer Patients After Self-Application of EFT (Emotional Freedom Techniques)
Status: ACTIVE_NOT_RECRUITING
Conditions: Depression
Interventions: BEHAVIORAL: Lifestyle Counseling with Emotional Freedom Techniques (EFT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Nicotinamide Versus Sevelamer Hydrochloride on Phosphatemia Control on Chronic Hemodialysed Patients
Status: TERMINATED
Conditions: Chronic Renal Failure|Hemodialysis
Interventions: DRUG: nicotinamide|DRUG: sevelamer|DRUG: cinacalcet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single Dose Study of PF-06815345 in Healthy Subjects
Status: TERMINATED
Conditions: Hypercholesterolemia
Interventions: DRUG: PF-06815345|OTHER: Placebo|DRUG: PF-06815345
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Safety and Efficacy Study of SB1518 for the Treatment of Advanced Lymphoid Malignancies
Status: COMPLETED
Conditions: Hodgkin Lymphoma|Mantle Cell Lymphoma|Indolent Lymphoma
Interventions: DRUG: SB1518
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: APC8015 and Bevacizumab in Treating Patients With Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: BIOLOGICAL: bevacizumab|BIOLOGICAL: prostatic acid phosphatase-sargramostim fusion protein|BIOLOGICAL: sipuleucel-T|BIOLOGICAL: therapeutic autologous dendritic cells|PROCEDURE: in vitro-treated peripheral blood stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: NEUWAVE Flexible Probe Study #2
Status: WITHDRAWN
Conditions: Cancer of the Lung|Lung Cancer|Neoplasms, Lung|Carcinoma, Non-Small Cell Lung|Non-Small Cell Lung Cancer|Non-Small Cell Lung Carcinoma
Interventions: DEVICE: Microwave ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Six-minute Stepper Test as an Outcome Measure of Exercise Tolerance During Pulmonary Rehabilitation in With Chronic Obstructive Pulmonary Disease (COPD) Patients(STEPPER)?
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: PROCEDURE: Pulmonary rehabilitation assessed with six-minute walk test and six-minute stepper test
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Efficacy of Everolimus in Reducing Total Native Kidney Volume in Polycystic Kidney Disease Transplanted Recipients
Status: COMPLETED
Conditions: Autosomal Dominant Polycystic Kidney Disease
Interventions: DRUG: Everolimus|DRUG: Calcineurin inhibitors maintenance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Impact of RPh201 on CVS Patients: Clinical and fMRI Measurements
Status: WITHDRAWN
Conditions: Chronic Vegetative State
Interventions: DIETARY_SUPPLEMENT: RPh201|DIETARY_SUPPLEMENT: saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Stigma and Efficacy of Zhizhu Kuanzhong Capsules
Status: UNKNOWN
Conditions: Functional Gastrointestinal Disorders|Dyspepsia|Psychosomatic Disorder
Interventions: DRUG: Zhizhu Kuanzhong capsules (ZZKZ)|DRUG: Doxepin Hydrochloride (Doxepin)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Novel Approach for Horizontal Augmentation: A Split Box
Status: COMPLETED
Conditions: Alveolar Bone Loss|Alveolar Ridge Augmentation|Augmentation, Alveolar Ridge
Interventions: PROCEDURE: Splitting of bone and fixation of bone laminae differ between the 3 groups.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Long-term Extension Study to Assess Vamorolone in Boys With Duchenne Muscular Dystrophy (DMD)
Status: COMPLETED
Conditions: Duchenne Muscular Dystrophy
Interventions: DRUG: Vamorolone 0.25 mg/day/day|DRUG: Vamorolone 0.75 mg/day/day|DRUG: Vamorolone 2.0 mg/day/day|DRUG: Vamorolone 6.0 mg/day/day
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open Label Pharmacokinetic-Pharmacogenetic Study on Polymorphisms in the Organic Cation Transporter OCT1
Status: COMPLETED
Conditions: Drug Metabolism|Membrane Transport
Interventions: DRUG: Drug application Amitriptyline|DRUG: Drug application Desvenlafaxine|DRUG: Drug application Sumatriptan|DRUG: Drug application Proguanil|DRUG: Drug application Fenoterol|DRUG: Drug application Thiamine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effectiveness of Inhaled Corticosteroids in Preschool Children With Acute Dyspnea and Wheeze
Status: TERMINATED
Conditions: Wheezing|Dyspnea
Interventions: DRUG: Beclomethasone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Pharmacokinetics and Safety of Org 25969 in Subjects With Normal or Impaired Renal Function (19.4.304)(P05948)(COMPLETED)
Status: COMPLETED
Conditions: Anesthesia, General
Interventions: DRUG: Sugammadex
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety and Dose-finding Study of JNJ-26483327, a Drug in Development for Cancer, for Patients With Advanced and/or Refractory Solid Malignancies.
Status: COMPLETED
Conditions: Protein Kinase Inhibitors|Antineoplastic Protocols|Clinical Trial, Phase 1|Maximum Tolerated Dose|Pharmacokinetics|Advanced Malignancies|Solid Malignancies
Interventions: DRUG: JNJ-26483327
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Examination of the Impact of CalmiGo's Stress Management Device on Vascular Heath and Cardiovascular Disease Risk.
Status: RECRUITING
Conditions: Myocardial Infarction
Interventions: DEVICE: CalmioGO Stress management device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Palatal Crib Versus Bonded Spurs in Early Treatment of Anterior Open Bite Caused by Non-nutritive Sucking Habits: RCT
Status: UNKNOWN
Conditions: Anterior Open Bite
Interventions: DEVICE: Palatal Crib|DEVICE: bonded spur
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase II Clinical Study to Assess the Efficacy and Safety of IBI310 or Placebo Combined With Sintilimab for Advanced Cervical Cancer Subjects Who Have Failed or Cannot Tolerate First-line or Above Platinum-based Chemotherapy
Status: COMPLETED
Conditions: Advanced Cervical Cancer
Interventions: DRUG: IBI310|DRUG: Placebo|DRUG: Sintilimab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mobile Health (mHealth) Tools to Improve Delivery Quality of a Family Home Visiting Intervention
Status: COMPLETED
Conditions: Parent-Child Relations|Behavioral Intervention|Exposure to Violent Event|Child Development|Mental Health|Implementation Science|mHealth|Community Health Workers
Interventions: BEHAVIORAL: Family Strengthening Intervention for Early Childhood Development|OTHER: Community Health Worker Routine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study of the Safety and Efficacy of RGH-896 in Patients With Diabetic Peripheral Neuropathic Pain
Status: COMPLETED
Conditions: Diabetic Peripheral Neuropathic Pain
Interventions: DRUG: RGH-896|DRUG: RGH-896|DRUG: RGH-896|DRUG: pregabalin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Allogeneic ABCB5-positive Limbal Stem Cells for Treatment of LSCD
Status: ACTIVE_NOT_RECRUITING
Conditions: Limbal Stem Cell Deficiency
Interventions: BIOLOGICAL: LSC2
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Internet-based Cognitive Behavior Therapy (CBT) for Obsessive Compulsive Disorder (OCD)
Status: COMPLETED
Conditions: Obsessive Compulsive Disorder
Interventions: BEHAVIORAL: Internet-based cognitive behavior therapy|BEHAVIORAL: Support therapy on Internet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sensor-based Balance Training With Exergaming Biofeedback
Status: COMPLETED
Conditions: Stroke, Ischemic
Interventions: DEVICE: Sensor-based Balance Training|OTHER: Usual Balance Trainging
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Gabapentin With or Without Antidepressants in Treating Hot Flashes in Women Who Have Had Breast Cancer or Have Concerns About Taking Hormone Therapy
Status: COMPLETED
Conditions: Breast Cancer|Hot Flashes
Interventions: DRUG: gabapentin|DRUG: antidepressant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Multi-center RCT of IV Ketamine Efficacy and Safety in Chronic Daily Headaches
Status: RECRUITING
Conditions: Chronic Daily Headache
Interventions: DRUG: Ketamine|OTHER: 0.9% Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: G-CSF+DAC+BUCY vs G-CSF+DAC+BF Conditioning Regimen for Secondary Acute Myeloid Leukemia Undergoing Allo-HSCT
Status: RECRUITING
Conditions: Secondary Acute Myeloid Leukemia Evolving From MDS|Allogeneic Hematopoietic Stem Cell Transplantation|Conditioning
Interventions: DRUG: Granulocyte Colony-Stimulating Factor(G-CSF)|DRUG: Decitabine (DAC)|DRUG: Busulfan (BU)|DRUG: Fludarabine (FLU)|DRUG: Cyclophosphamide (CY)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pharmacokinetic Study of RO5185426 in Combination With a Drug Cocktail in Patients With Metastatic Melanoma
Status: COMPLETED
Conditions: Malignant Melanoma
Interventions: DRUG: Drug cocktail|DRUG: RO5185426
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy/Safety Study of Nebulized IVX-0142, a Novel Antiallergic Drug, in Mild Allergic Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Nebulized IVX-0142
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Safety and Tolerability of Metacavir Enteric-coated Capsules in Healthy Adult Volunteers
Status: COMPLETED
Conditions: Chronic Hepatitis B
Interventions: DRUG: PNA 40mg|DRUG: PNA 80mg|DRUG: PNA 160mg|DRUG: PNA 240mg|DRUG: PNA 360mg|DRUG: PNA 480mg|DRUG: PNA Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study to Obtain Preliminary Information Regarding the Efficacy and Safety of the Combination of Immune Globulin and Ganciclovir as Compared to Ganciclovir Alone in the Treatment of Sight-Threatening CMV Retinitis in Patients With AIDS
Status: COMPLETED
Conditions: Cytomegalovirus Retinitis|HIV Infections
Interventions: DRUG: Globulin, Immune|DRUG: Ganciclovir
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Study of the Safety, Tolerability, Pharmacokinetics and Pharmacodynamic Properties of Oral AT-406 in Combination With Daunorubicin and Cytarabine in Patients With Poor-risk Acute Myelogenous Leukemia (AML)
Status: TERMINATED
Conditions: Acute Myelogenous Leukemia (AML)
Interventions: DRUG: AT-406 in combination with daunorubicin and cytarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Nitroglycerin Infusion Rate on Cerebral Rewarming During Hypothermic Coronary Artery Bypass Grafting
Status: COMPLETED
Conditions: Coronary Artery Bypass|Cardiopulmonary Bypass
Interventions: DRUG: Glyceryl trinitrate 0.2|DRUG: Glyceryl trinitrate 0.5
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Efficacy Study of Sitagliptin to Prevent New-onset Diabetes After Kidney Transplant
Status: COMPLETED
Conditions: Posttransplant Diabetes Mellitus
Interventions: DRUG: Sitagliptin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Daily Erythritol Versus Sucrose Intake Over 5 Weeks on Glucose Tolerance in Adolescents
Status: RECRUITING
Conditions: Insulin Resistance|Glucose Tolerance|Body Composition|Gastrointestinal Tolerance|Thrombocyte Aggregation|Blood p-Selectin|Blood Erythritol|Blood Xylitol
Interventions: DIETARY_SUPPLEMENT: Eryhtritol|DIETARY_SUPPLEMENT: Sucrose|DIETARY_SUPPLEMENT: Glucose|DIETARY_SUPPLEMENT: Fructose|DIETARY_SUPPLEMENT: Xylitol|DIETARY_SUPPLEMENT: Water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Autologous CAR-T Cells Targeting B7H3 in Ovarian Cancer iC9-CAR.B7-H3 T Cells
Status: RECRUITING
Conditions: Ovary Neoplasm|Ovarian Cancer|Epithelial Ovarian Cancer|Recurrent
Interventions: BIOLOGICAL: iC9-CAR.B7-H3 T cells|DRUG: Cyclophosphamide|DRUG: Fludarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Vasomotor Symptoms in Korean Post Menopausal Women
Status: COMPLETED
Conditions: Vasomotor Symptoms
Interventions: DRUG: Angeliq (Drospirenone/17ß-estradiol, BAY86-4891)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transcutaneous Electrical Nerve Stimulation on Nervous System in Patients With Hypertension.
Status: UNKNOWN
Conditions: Cardiovascular Diseases
Interventions: DEVICE: TENS High Frequency|DEVICE: TENS Low Frequency|DEVICE: TENS Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Obstructive Sleep Apnea in World Trade Center Responders
Status: COMPLETED
Conditions: Obstructive Sleep Apnea
Interventions: DEVICE: Standard CPAP|DEVICE: CPAP - Flex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of LiveSpo Navax in Supportive Treatment of Pneumonia in Children With RSV and Bacterial Co-infections
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Respiratory Tract Infections|Pneumonia|Respiratory Syncytial Virus (RSV)
Interventions: DRUG: 0.9% NaCl physiological saline|COMBINATION_PRODUCT: LiveSpo Navax
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pulsed Electromagnetic Fields for Postoperative Pain: a Linical Trial in Humans
Status: COMPLETED
Conditions: Pain|Oral Surgery|Third Molar Extraction
Interventions: DEVICE: RecoveryRx™
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Sacituzumab Govitecan-hziy Versus Treatment of Physician's Choice in Patients With Previously Untreated Locally Advanced Inoperable or Metastatic Triple-Negative Breast Cancer
Status: RECRUITING
Conditions: Triple Negative Breast Cancer|PD-L1 Negative
Interventions: DRUG: Sacituzumab Govitecan-hziy|DRUG: Paclitaxel|DRUG: nab-Paclitaxel|DRUG: Gemcitabine|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Perioperative Closed-loop Glucose Control
Status: COMPLETED
Conditions: Perioperative Hyperglycaemia|Insulin Therapy|Elective Surgery|Closed-Loop Glucose Control|Artificial Pancreas
Interventions: DEVICE: CamAPS|DRUG: Standard insulin therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Prospective Open Label Comparative Dose Ranging Study Evaluating the Effect of Pre-TURBT Intravesical Instillation of Mitomycin C (MMC) Mixed With TC-3 Gel in Patients With Non Muscle Invasive Bladder Cancer (NMIBC)
Status: WITHDRAWN
Conditions: Non Muscle Invasive Bladder Cancer
Interventions: DEVICE: TC-3 hydrogel|DEVICE: TC-3 hydrogel|DEVICE: TC-3 hydrogel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rhomboid Flap Versus Primary Closure After Excision of Sacrococcygeal Pilonidal Sinus. (A Prospective Randomized Study)
Status: WITHDRAWN
Conditions: Evaluate and Compare Between Excision and Primary Closure Procedure and Rhomboid Flap Technique for the Treatment of Pilonidal Sinus|Duration of Operation,
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of the Success Rate of Two Approaches for Obturator Nerve Block in TURB (Conventional Pubic Approach [Labat Technique] and Inguinal Approach)
Status: COMPLETED
Conditions: Nerve Block
Interventions: PROCEDURE: obturator nerve block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: |Primary Purpose:
Clinical trial: Adoptive Immunotherapy of High Risk Acute Myeloblastic Leukemia Patients Using Haploidentical Kir Ligand-mismatched Natural Killer Cells
Status: UNKNOWN
Conditions: Myeloblastic Leukemia
Interventions: BIOLOGICAL: NK cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 1.2% Rosuvastatin Subgingivally Delivered In Chronic Periodontitis With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Chronic Periodontitis|Type2 Diabetes
Interventions: DRUG: SRP plus Rosuvastatin gel|DRUG: SRP plus placebo gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pre-Symptomatic Study of Intravenous Onasemnogene Abeparvovec-xioi in Spinal Muscular Atrophy (SMA) for Patients With Multiple Copies of SMN2
Status: COMPLETED
Conditions: Spinal Muscular Atrophy
Interventions: BIOLOGICAL: onasemnogene abeparvovec-xioi
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Maternal Opioid Treatment: Human Experimental Research - Data Yield Appropriate Decisions
Status: COMPLETED
Conditions: Opioid-use Disorder|Opioid Withdrawal|Neonatal Abstinence Syndrome|Neonatal Opioid Withdrawal Syndrome
Interventions: OTHER: Medically-supervised withdrawal|OTHER: Opioid agonist treatment|BEHAVIORAL: Comprehensive clinical care
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Vaccine Therapy in Treating Patients With Resected or Locally Advanced Unresectable Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: BIOLOGICAL: MUC1 antigen/SB AS-2
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility of a Home Exercise Program With the Addition of a Corticosteroid Injection in Patients With Lateral Hip Pain
Status: RECRUITING
Conditions: Greater Trochanteric Pain Syndrome
Interventions: DRUG: Ultrasound-guided corticosteroid injection|BEHAVIORAL: Home exercise program|BEHAVIORAL: Patient information leaflet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: S8516-S8736-S9125-S9240 Research Study of Genes in Tissue Samples From Patients With B-cell Non-Hodgkin Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: GENETIC: polymorphism analysis|OTHER: laboratory biomarker analysis|OTHER: pharmacogenomic studies
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: COMMIT (Combination Of Maintenance Methotrexate-Infliximab Trial)
Status: COMPLETED
Conditions: Crohn's Disease
Interventions: DRUG: Methotrexate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Cow Milk Consumption on Respiratory Symptoms and Pulmonary Functions in Asthmatic and Non Asthmatic Children
Status: UNKNOWN
Conditions: Asthma
Interventions: DIETARY_SUPPLEMENT: Cow milk|DIETARY_SUPPLEMENT: Soy milk
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SCREENING
Clinical trial: Restoration of Non-carious Cervical Lesions With Different Resin Composites and Universal Adhesive
Status: RECRUITING
Conditions: Retention of Restorations
Interventions: PROCEDURE: NCCL restoration using resin composite materials
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 600 mg Amoxicillin/42.9 mg Clavulanate Postassium /5 mL Suspension Under Fasting Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: 600 mg Amoxicillin/42.9 mg Clavulanate Postassium /5 mL|DRUG: Augmentin ES-600™ 600 mg/42.9 mg/5 mL Suspension
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Suprascapular Nerve Block for Treatment of Shoulder Pain in Individuals With Spinal Cord Injuries
Status: WITHDRAWN
Conditions: Chronic Shoulder Pain
Interventions: DRUG: Lidocaine 1% Injectable Solution|DRUG: Triamcinolone Injection|PROCEDURE: Suprascapular Nerve Block
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Megestrol to Limit Weight Loss and Improve Quality of Life in Treating Patients With Head and Neck Cancer
Status: COMPLETED
Conditions: Anorexia|Cachexia|Head and Neck Cancer|Quality of Life
Interventions: DRUG: megestrol acetate|PROCEDURE: quality-of-life assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Biological, Prospective Study Evaluating the Dosage of Plasma Cytokines Including the FLT3 Ligand and IL6 of Patients Treated With Non-intensive Chemotherapy
Status: NOT_YET_RECRUITING
Conditions: Acute Myeloid Leukemia|Myelodysplastic Syndromes|Chronic Myelomonocytic Leukemia
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Nevirapine and Prednisone to Determine the Safety and Effectiveness in Preventing Nevirapine Associated Rash in Human Immunodeficiency Virus (HIV) Infected Patients
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Nevirapine|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevention of Neovascular Glaucoma by Intravitreal Injections of Anti-VEGF in Patients Treated With Proton Therapy for a Large Choroidal Melanoma
Status: RECRUITING
Conditions: Ocular Melanoma
Interventions: DRUG: Aflibercept Injection|DRUG: False injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Internet-CBT for Insomnia
Status: COMPLETED
Conditions: Insomnia|Depression
Interventions: BEHAVIORAL: Therapist guided Internet-CBT for insomnia|BEHAVIORAL: Brief Internet-CBT for insomnia, without support|BEHAVIORAL: Therapist Guided Internet-CBT for depression
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The PK Characteristics of the Co-administration of Rosuvastatin and Telmisartan/Amlodipine and JLP-1401 in Healthy Adult Volunteers Volunteers
Status: COMPLETED
Conditions: Hypertension With Dyslipidemia
Interventions: DRUG: JLP-1401|DRUG: Telmisartan/Amlodipine, Rosuvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Cryotherapy Versus Post-operative Ibuprofen Medication on Post-operative Pain in Mandibular Molar Teeth With Symptomatic Irreversible Pulpitis
Status: UNKNOWN
Conditions: Symptomatic Irreversible Pulpitis
Interventions: OTHER: cold saline (cryotherapy)|DRUG: Ibuprofen 400 mg|OTHER: Final irrigation with normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Iron Administration Via Colonic TET Combined With WMT for ID
Status: NOT_YET_RECRUITING
Conditions: Iron Deficiency Anemia in Childbirth
Interventions: DRUG: Ferrous Lactate|DRUG: Iron sucrose|DRUG: 0.9% NaCl solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Food Form and Fitness on Appetite and Digestion.
Status: COMPLETED
Conditions: High and Increasing Contribution of Energy From Beverages in the Diet May Enhance Positive Energy Balance and Weight Gain
Interventions: BEHAVIORAL: liquid to liquid|BEHAVIORAL: liquid to solid|BEHAVIORAL: solid to liquid|BEHAVIORAL: solid to solid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Serum Estradiol Levels In Postmenopausal Women With Breast Cancer Receiving Adjuvant Aromatase Inhibitors and Vaginal Estrogen
Status: COMPLETED
Conditions: Atrophic Vaginitis|Breast Cancer
Interventions: DRUG: Vagifem® (vaginal 17β-estradiol) questionnaire & menopause symptom checklist
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Bimagrumab on Body Composition, Insulin Sensitivity, and Bone in Adults With Obesity
Status: NOT_YET_RECRUITING
Conditions: Obesity
Interventions: DRUG: IV bimagrumab|DRUG: IV placebo|DRUG: Semaglutide|DIETARY_SUPPLEMENT: Calcium/Vitamin D|BEHAVIORAL: Lifestyle and nutrition counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of MgSO4 Pretreatment on Muscle Relaxation
Status: RECRUITING
Conditions: Muscle Relaxation
Interventions: DRUG: Magnesium Sulphate|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Reducing Post Operative Bleeding Following Cabg
Status: COMPLETED
Conditions: Post CABG Bleeding
Interventions: DRUG: Tranexamic Acid|DRUG: saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT