pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Intravenous Erythromycin Before Endoscopy in Patients With Variceal Bleeding: A Randomized, Double-Blind Trial
Status: COMPLETED
Conditions: Variceal Bleeding
Interventions: DRUG: Erythromycin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Compare Immunological Efficacy of a Vaccine Regimen Combining Two Covid19 mRNA Vaccines (Pfizer-BioNTech and Moderna) With That of a Homologous Vaccination of Each Covid19 mRNA Vaccine
Status: UNKNOWN
Conditions: Adult Who Received a First Dose of an mRNA Vaccine (Pfizer-BioNTech or Moderna) and Need to Receive a Second Dose
Interventions: BIOLOGICAL: Pfizer|BIOLOGICAL: Moderna
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Intensity-Modulated or Proton Radiation Therapy for Sinonasal Malignancy
Status: ACTIVE_NOT_RECRUITING
Conditions: Adenoid Cystic Carcinoma|Squamous Cell Carcinoma|Sinonasal Carcinoma|Sinonasal Undifferentiated Carcinoma|Mucoepidermoid Carcinoma|Schneiderian Carcinoma|Myoepithelial Carcinoma|Esthesioneuroblastoma|Melanoma
Interventions: RADIATION: Proton radiation therapy|RADIATION: Intensity-modulated radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Primary Breast Cancer Occurring Concomitant With Pregnancy
Status: COMPLETED
Conditions: Breast Cancer|Pregnancy
Interventions: DRUG: 5-Fluorouracil|DRUG: Cyclophosphamide|DRUG: Doxorubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Priming With tDCS: Expanding the Window of Recovery in Chronic Stroke
Status: ACTIVE_NOT_RECRUITING
Conditions: Upper Extremity Paresis
Interventions: DEVICE: transcranial direct current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy of Bevacizumab Plus Irinotecan in Recurrent Gliomas
Status: COMPLETED
Conditions: Glioblastoma|Astrocytoma
Interventions: DRUG: Bevacizumab/Irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Dalcetrapib in Patients With Confirmed Mild to Moderate COVID-19
Status: COMPLETED
Conditions: Covid19
Interventions: DRUG: Dalcetrapib|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Reducing Edema After intraCerebral Hemorrhage
Status: NOT_YET_RECRUITING
Conditions: Edema Brain
Interventions: DRUG: Sodium Aescinate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Post-Market Evaluation of LipiFlow Treatment in Cataract Surgery Practice
Status: COMPLETED
Conditions: Cataracts|Meibomian Gland Dysfunction (MGD)
Interventions: DEVICE: LipiFlow Thermal Pulsation System|DEVICE: LipiFlow Thermal Pulsation System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Bismuth Containing Quadruple Therapy and Based Tailored Therapy for H. Pylori Infection
Status: UNKNOWN
Conditions: Helicobacter Pylori Infection|Compliance, Patient|Drug Resistance|Antibiotics
Interventions: DIAGNOSTIC_TEST: Helicobacter pylori PCR test|DIAGNOSTIC_TEST: CLO test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Remote Monitoring of Axial Spondyloarthritis
Status: COMPLETED
Conditions: Axial Spondyloarthritis
Interventions: OTHER: Usual care|OTHER: Remote monitoring|OTHER: Patient-initiated care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study of Retatrutide (LY3437943) Once Weekly in Participants Who Have Obesity or Overweight and Osteoarthritis of the Knee
Status: ACTIVE_NOT_RECRUITING
Conditions: Obesity|Overweight|Osteo Arthritis Knee
Interventions: DRUG: Retatrutide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: STORM: Temsirolimus, Rituximab and DHAP for Relapsed and Refractory Diffuse Large B-cell Lymphoma
Status: UNKNOWN
Conditions: Diffuse Large B-Cell Lymphoma
Interventions: DRUG: Rituximab, Temsirolimus, DHAP, intravenous
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Apposition Assessed Using Optical Coherence Tomography of Chromium Stents Eluting Everolimus From Cobalt Versus Platinum Alloy Platforms
Status: UNKNOWN
Conditions: Coronary Artery Disease
Interventions: DEVICE: Everolimus eluting stents
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Safety, Efficacy and Tolerability Study of up to 20 mL of DFA-02 in Patients Undergoing Abdominal Surgery
Status: COMPLETED
Conditions: Surgical Site Infections
Interventions: DRUG: DFA-02 Antibiotic Gel|DRUG: DFA-02 Placebo Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: An Evaluation of Pain Outcomes of Ketorolac Administration in Children Undergoing Circumcision
Status: COMPLETED
Conditions: Pain, Postoperative|Phimosis|Paraphimosis|Balanitis
Interventions: DRUG: Bupivacain|DRUG: Sevoflurane|DRUG: Acetaminophen|DRUG: Ibuprofen|DRUG: Ketorolac
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Combined N-of-1 Trials Mexiletine vs Placebo in Patients With Non-Dystrophic Myotonia (NDM)
Status: COMPLETED
Conditions: Non Dystrophic Myotonia
Interventions: DRUG: Mexiletine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cervicothoracic Junction Mobilization Versus Eccentric Muscle Energy Technique in Mechanical Cervical Pain
Status: COMPLETED
Conditions: Neck Pain
Interventions: OTHER: Cervicothoracic Junction Mobilization Technique|OTHER: Eccentric Muscle Energy Technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Pancreatic Cancer Detection Consortium
Status: RECRUITING
Conditions: Pancreatic Cancer|Pancreatic Carcinoma|Pancreatic Adenocarcinoma|Pancreatic Ductal Adenocarcinoma|Pancreatic Neoplasms|Pancreatic Cancer Stage I|Pancreatic Cancer Stage|Pancreatic Cancer Resectable|Pancreatic Cancer Stage 0|Pancreatic Cancer Stage II|Pancreatic Cancer Stage III|Pancreatic Cancer, Adult|Pancreatic Cancer Non-resectable
Interventions: DIAGNOSTIC_TEST: PANcreatic cancer Exosome Early detectiON (PANXEON)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Reconstructive Management of Peri-implantitis
Status: UNKNOWN
Conditions: Resolution of Pathologic Process
Interventions: PROCEDURE: Reconstructive therapy of peri-implantitis by means of bone graft (and barrier membrane in the test group)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I Study of Sequential Cord Blood Transplants
Status: COMPLETED
Conditions: Lymphoma|Leukemia|Multiple Myeloma|Myelodysplastic Syndrome
Interventions: PROCEDURE: sequential cord blood transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Open-Label Study to Evaluate the Metabolism and Excretion of CC-223 and the Effect of Food on the Pharmacokinetics of CC-223 in Healthy Male Adult Subjects
Status: COMPLETED
Conditions: Safety and Pharmacokinetics in Healthy Volunteer Subjects
Interventions: DRUG: CC-223|DRUG: CC-223
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Nursing Interventions on Stroke Patient Care: Quality of Life, Hopelessness, Anxiety and Depression
Status: NOT_YET_RECRUITING
Conditions: Stroke|Depression|Anxiety|Care Burden|Hopefulness
Interventions: BEHAVIORAL: Nursing Interventions for Stroke Patient Care
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Influence of Sugar on the Bioavailability of Cocoa Flavanols
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Low flavanol chocolate|DIETARY_SUPPLEMENT: High-flavanol with sugar|DIETARY_SUPPLEMENT: High flavanol Maltitol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Evaluate the Safety and Efficacy of Omarigliptin (MK-3102) Compared With Glimepiride in Participants With Type 2 Diabetes Mellitus for Whom Metformin is Inappropriate (MK-3102-027)
Status: TERMINATED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Omarigliptin|DRUG: Glimepiride|DRUG: Omarigliptin Placebo|DRUG: Glimepiride Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Safety and Efficacy of Multiple Dosing With VB10.NEO and Bempegaldesleukin (NKTR-214) Immunotherapy in Patients With Locally Advanced or Metastatic Cancer
Status: COMPLETED
Conditions: Locally Advanced or Metastatic Solid Tumours
Interventions: BIOLOGICAL: VB10.NEO|DRUG: Bempegaldesleukin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Safety and Immunogenicity of GlaxoSmithKline (GSK) Biologicals' Herpes Zoster Subunit (HZ/su) Vaccine in Adults Aged 18 Years and Older With Blood Cancers
Status: COMPLETED
Conditions: Herpes Zoster
Interventions: BIOLOGICAL: Herpes zoster vaccine (GSK 1437173A)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of De-Epithelialized Gingival Graft With or Without Platelet Rich Fibrin in Multiple Gingival Recessions
Status: COMPLETED
Conditions: Gingival Recession, Generalized
Interventions: PROCEDURE: DGG+PRF|PROCEDURE: DGG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Safety and Pharmacokinetics of GDC-0152, Administered Intravenously to Patients With Locally Advanced or Metastatic Malignancies
Status: TERMINATED
Conditions: Solid Cancers
Interventions: DRUG: GDC-0152
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Three Times Per Week (TIW) Oral Dosing of Vadadustat for Anemia in Subjects With Dialysis-Dependent Chronic Kidney Disease (DD-CKD)
Status: WITHDRAWN
Conditions: Anemia|Dialysis-Dependent Chronic Kidney Disease
Interventions: DRUG: Vadadustat|DRUG: Darbepoetin alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ramelteon in Adults With Chronic Insomnia
Status: COMPLETED
Conditions: Chronic Insomnia
Interventions: DRUG: Ramelteon|DRUG: Ramelteon|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Support Annual Strain Update, Safety and Immunogenicity of an Inactivated, Adjuvanted Influenza Vaccine, Formulation 2007-2008, When Administered to Subjects 18-64 Years Affected by Chronic Diseases.
Status: COMPLETED
Conditions: Influenza Disease
Interventions: BIOLOGICAL: Adjuvanted influenza vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: High-frequency vs. Low-frequency vs. Sham DMPFC-rTMS for Bulimia and Anorexia Nervosa
Status: TERMINATED
Conditions: Bulimia Nervosa|Anorexia Nervosa
Interventions: DEVICE: High-frequency rTMS|DEVICE: Low-frequency rTMS|DEVICE: Sham rTMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cervical Sensorimotor Control Training in Chronic Neck Pain
Status: COMPLETED
Conditions: Nonspecific Chronic Neck Pain
Interventions: OTHER: Cervical sensorimotor control training exercises|OTHER: Conventional Exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Impact of Lipoic Acid Use on Stroke Outcome After Reperfusion Therapy in Patients With Diabetes (IMPORTANT)
Status: UNKNOWN
Conditions: Stroke, Ischemic
Interventions: DRUG: alpha lipoic acid|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess Safety & Efficacy of GKT137831 in Patients With Primary Biliary Cholangitis Receiving Ursodiol.
Status: COMPLETED
Conditions: Primary Biliary Cirrhosis
Interventions: DRUG: GKT137831|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: NODE (groiN ultrasOunD cancEr)
Status: NOT_YET_RECRUITING
Conditions: Vulvar Cancer Stage Ib|Vulvar Cancer Stage II|Lymph Node Metastasis|Groin Node|Ultrasound Therapy; Complications
Interventions: DIAGNOSTIC_TEST: High-resolution bilateral groin ultrasound surveillance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Radiation Therapy With or Without Combination Chemotherapy or Pazopanib Before Surgery in Treating Patients With Newly Diagnosed Non-rhabdomyosarcoma Soft Tissue Sarcomas That Can Be Removed by Surgery
Status: ACTIVE_NOT_RECRUITING
Conditions: Alveolar Soft Part Sarcoma|Angiomatoid Fibrous Histiocytoma|Atypical Fibroxanthoma|Clear Cell Sarcoma of Soft Tissue|Epithelioid Malignant Peripheral Nerve Sheath Tumor|Epithelioid Sarcoma|Extraskeletal Myxoid Chondrosarcoma|Extraskeletal Osteosarcoma|Fibrohistiocytic Neoplasm|Fibrosarcoma|Inflammatory Myofibroblastic Tumor|Intimal Sarcoma|Leiomyosarcoma|Liposarcoma|Liver Embryonal Sarcoma|Low Grade Fibromyxoid Sarcoma|Low Grade Myofibroblastic Sarcoma|Malignant Peripheral Nerve Sheath Tumor|Malignant Skin Granular Cell Tumor|Malignant Triton Tumor|Mesenchymal Chondrosarcoma|Myxofibrosarcoma|Myxoid Chondrosarcoma|Myxoinflammatory Fibroblastic Sarcoma|Nerve Sheath Neoplasm|PEComa|Pericytic Neoplasm|Plexiform Fibrohistiocytic Tumor|Sclerosing Epithelioid Fibrosarcoma|Skin Glomus Tumor|Stage IB Soft Tissue Sarcoma AJCC v7|Stage IIB Soft Tissue Sarcoma AJCC v7|Stage III Soft Tissue Sarcoma AJCC v7|Stage IV Soft Tissue Sarcoma AJCC v7|Synovial Sarcoma|Undifferentiated High Grade Pleomorphic Sarcoma of Bone
Interventions: DRUG: Doxorubicin|DRUG: Doxorubicin Hydrochloride|DRUG: Ifosfamide|DRUG: Pazopanib|DRUG: Pazopanib Hydrochloride|RADIATION: Radiation Therapy|PROCEDURE: Therapeutic Conventional Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose-ranging Study of Vilanterol (VI) Inhalation Powder in Children
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Fluticasone propionate 100mcg|DRUG: Placebo|DRUG: Vilanterol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Cabazitaxel in Patients With Brain Metastasis Secondary to Breast Cancer and NSCLC
Status: WITHDRAWN
Conditions: Brain Metastasis|Breast Cancer|Non Small Cell Lung Cancer
Interventions: DRUG: Cabazitaxel|PROCEDURE: Contrast-enhanced whole brain MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tislelizumab Plus Chemotherapy as Postoperative Adjuvant Therapy in Elderly Patients With LA GC/GEJC
Status: NOT_YET_RECRUITING
Conditions: Gastric Cancer
Interventions: DRUG: Tislelizumab|DRUG: S-1 therapy|DRUG: low dose SOX therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Anti-PD-1/CTLA-4 Bispecific AK104 Plus Lenvatinib in First-line Advanced Hepatocellular Carcinoma
Status: COMPLETED
Conditions: Hepatocellular Carcinoma
Interventions: BIOLOGICAL: AK104|DRUG: Lenvatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Outpatient Ultrasound for the Diagnostic Work-up of Oropharynx Cancer
Status: COMPLETED
Conditions: Oropharynx Cancer|Oropharynx Neoplasm|Tonsil Cancer|Tonsil Neoplasm|Tonsil Hypertrophy|Tonsil Lymphoma|Base of Tongue Tumor|Base of Tongue Carcinoma
Interventions: DIAGNOSTIC_TEST: Transoral ultrasound|DIAGNOSTIC_TEST: Transcervical ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy of Split-dose of Oral MMS for Bowel Preparation in Elderly Patients
Status: COMPLETED
Conditions: Colonic Adenoma|Bowel Preparation
Interventions: OTHER: split-dose of Magnesium Sulfate solution|OTHER: split-dose of PEG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: CB-839 With Everolimus vs. Placebo With Everolimus in Participants With Renal Cell Carcinoma (RCC)
Status: COMPLETED
Conditions: Clear Cell Renal Cell Carcinoma
Interventions: DRUG: Placebo|DRUG: CB-839|DRUG: everolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparison Between GLA:D Canada and an Individualized JointEffort Exercise Program in Knee Osteoarthritis Patients
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: OTHER: GLA:D Canada Program|OTHER: JointEffort Program
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Patient-driven Internet Delivered Psychological Treatment
Status: COMPLETED
Conditions: Anxiety Disorders and Symptoms|Internet-Based Intervention
Interventions: BEHAVIORAL: Patient-driven iCBT|BEHAVIORAL: Standardized iCBT (TAU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison Between RCT in Single and Two Visits, With and Without Intracanal Dressing, in Apical Repair
Status: UNKNOWN
Conditions: Teeth, Endodontically-Treated|Tooth, Nonvital|Periapical Periodontitis, Chronic Nonsuppurative|Periapical Granuloma
Interventions: COMBINATION_PRODUCT: RCT-SV|OTHER: RCT-TVWD|OTHER: RCT-TVWOD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: PPSV23 Pneumococcal Vaccine in Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: BIOLOGICAL: PPSV23 pneumococcal vaccine (Pneumovax®)|DRUG: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: STEP-COVID: A Program for Pregnant Women During the SARS-CoV-2 Pandemic
Status: COMPLETED
Conditions: Psychological|Mental Health Issue|Prenatal Stress|Maternal Distress|COVID-19 Pandemic
Interventions: BEHAVIORAL: STEP-COVID
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: CYT107 After Vaccine Treatment (Provenge®) in Patients With Metastatic Castration-Resistant Prostate Cancer
Status: COMPLETED
Conditions: Castration Levels of Testosterone|Castration-Resistant Prostate Carcinoma|Metastatic Prostate Carcinoma|Stage IV Prostate Cancer
Interventions: BIOLOGICAL: Glycosylated Recombinant Human Interleukin-7|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Association Between Changes in the Gut Microbiome and Chemotherapy-Induced Nausea in Stage I-III Breast Cancer
Status: RECRUITING
Conditions: Chemotherapy-Related Nausea and/or Vomiting|Early Stage Breast Carcinoma
Interventions: PROCEDURE: Biospecimen Collection|OTHER: Questionnaire Administration
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Hypercapnic Spontaneous Hyperpnoea and Recovery From Sevoflurane Anesthesia
Status: COMPLETED
Conditions: Anesthesia|Surgery
Interventions: OTHER: Standard Anesthesia management for post surgical patients|DEVICE: Hypercarbic Spontaneous Hyperpnoea
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intervention Effect of TP and AOB-w on Acrylamide Exposure in Chinese Adolescents
Status: COMPLETED
Conditions: Intervention
Interventions: DIETARY_SUPPLEMENT: Tea polyphenols|DIETARY_SUPPLEMENT: AOB-w|OTHER: Placebo|OTHER: Acrylamide (Potato Chips)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Comparative Evaluation of Two AQUACEL Ag Protocols of Care for the Management of Donor Sites
Status: COMPLETED
Conditions: Split-Thickness Donor Sites.
Interventions: DEVICE: Aquacel Ag Gelled|DEVICE: Aquacel Ag Adherent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparison of an Ultra-thin and Standard Colonoscope in Achieving Caecal Intubation
Status: COMPLETED
Conditions: First Colonoscopy Examination
Interventions: PROCEDURE: Standard Colonoscopy|PROCEDURE: Ultra-thin colonoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Comparison of Oral Paracetamol and Zolmitriptan Efficacy in the Treatment of Acute Migraine in Emergency Department
Status: COMPLETED
Conditions: Acute Migraine Headache
Interventions: DRUG: Paracetamol|DRUG: Zolmitriptan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Safety and Tolerability of ACZ885 in Pediatric Patients With the Following Cryopyrin-associated Periodic Syndromes: Familial Cold Autoinflammatory Syndrome, Muckle-Wells Syndrome, or Neonatal Onset Multisystem Inflammatory Disease
Status: COMPLETED
Conditions: Cryopyrin-associated Periodic Syndromes|Familial Cold Autoinflammatory Syndrome|Muckle-Wells Syndrome|Neonatal Onset Multisystem Inflammatory Disease
Interventions: BIOLOGICAL: ACZ885
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: |Primary Purpose: TREATMENT
Clinical trial: A Study of Radiation Therapy to Treat Solid Tumor Cancer That Has Spread to Soft Tissue
Status: RECRUITING
Conditions: Invasive Ductal Breast Carcinoma|Invasive Ductal Breast Carcinoma Stage IV|Lobular Breast Carcinoma|Lobular Breast Carcinoma Stage IV|Non Small Cell Lung Cancer|NSCLC|Gastrointestinal Cancer|Gastrointestinal Squamous Cell Cancer|Gastrointestinal Adenocarcinoma|Pancreatic Cancer|Bladder Cancer|Renal Cell Carcinoma|Melanoma|Sarcoma|Metastatic Solid Tumor
Interventions: RADIATION: Stereotactic body radiotherapy|RADIATION: Lattice Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of a Structured Personalised Ergonomic Intervention for Hospital Nurses With Musculoskeletal Complains
Status: COMPLETED
Conditions: Musculoskeletal Diseases
Interventions: BEHAVIORAL: Ergonomic plan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Virtual Reality and Music on Pain, Anxiety, Itching, and Vital Signs
Status: COMPLETED
Conditions: Allergy|Anxiety|Pain|Itching|Vital Signs
Interventions: OTHER: The VR glasses group|OTHER: the music group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Study of INCMGA00012 in Participants With Selected Solid Tumors (POD1UM-203)
Status: COMPLETED
Conditions: Metastatic Non-small Cell Lung Cancer|Locally Advanced Urothelial Cancer|Metastatic Urothelial Cancer|Unresectable Melanoma|Metastatic Melanoma|Locally Advanced Renal Cell Carcinoma|Metastatic Clear-Cell Renal Cell Carcinoma
Interventions: DRUG: Retifanlimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Quaternary Ammonium and Immunization in Hairdressers
Status: TERMINATED
Conditions: Quaternary Ammonium|Hypersensitivity
Interventions: BIOLOGICAL: serum punction|BIOLOGICAL: skin swab in elbow folds
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study of Systemic and Spinal Chemotherapy Followed by Radiation for Infants With Brain Tumors
Status: COMPLETED
Conditions: Brain Tumors
Interventions: DRUG: Induction therapy (Regimen 1, Course 1, Cycle A1|DRUG: Regimen 1, Course 1, Cycle A2 (Days 22 - 42)|DRUG: Cycle B|DRUG: Regimen 1, Course 2|DRUG: Intrathecal Mafosfamide|DRUG: Regimen 1 Course 2, IT mafosfamide|DRUG: Regimen 2, Course 1|DRUG: Regimen 2, Course, 1, Cycle C1|DRUG: Regimen 2, Course 2|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vorinostat in Treating Patients With Recurrent or Persistent Ovarian Epithelial or Primary Peritoneal Cavity Cancer
Status: COMPLETED
Conditions: Primary Peritoneal Cavity Cancer|Recurrent Ovarian Epithelial Cancer
Interventions: DRUG: vorinostat
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Four Week Performance Comparison Between Two Commercially Available Silicone Hydrogel Lenses
Status: COMPLETED
Conditions: Myopia
Interventions: DEVICE: Lotrafilcon B contact lens (AIR OPTIX® AQUA)|DEVICE: Balafilcon A contact lens (PureVision® 2)|DEVICE: Contact lens solution (Clear Care®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Mechanisms of Metabolic Regulation of Resveratrol on Humans With Metabolic Syndrome
Status: WITHDRAWN
Conditions: Insulin Resistance
Interventions: DRUG: Placebo|DRUG: Resveratrol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Nintedanib Plus mFOLFOX6 for Previously Untreated Metastatic Esophagogastric Adenocarcinoma (MEGAN)
Status: WITHDRAWN
Conditions: Esophagogastric Adenocarcinoma|Metastatic Disease|No Previous Chemotherapy for Metastatic Esophagogastric Cancer
Interventions: DRUG: Nintedanib|DRUG: Fluorouracil|DRUG: Leucovorin|DRUG: Oxaliplatin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Meta-analyses of Dietary Pulses and Cardiometabolic Risk
Status: UNKNOWN
Conditions: Dyslipidemia|Diabetes|Prediabetes|Dysglycemia|Overweight|Obesity|Hypertension|Metabolic Syndrome|Cardiovascular Disease
Interventions: OTHER: Dietary pulses
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Clinical Study to Investigate the Mass Balance and Biotransformation of [14C]DWP14012 in Healthy Chinese Male Subjects
Status: ACTIVE_NOT_RECRUITING
Conditions: Phase 1 Study, Healthy Volunteers
Interventions: DRUG: [14C]DWP14012
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: HPI Algorithm for the Prevention of IOH During Spinal Surgery [HPIFPIOH]
Status: RECRUITING
Conditions: Intraoperative Hypotension
Interventions: DEVICE: HPI algorithm using Edwards device https://www.edwards.com/gb/devices/decision-software/hpi|DRUG: Vasoactive Agent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Manual Therapy Plus Capacitive and Resistive Electric Transfer Therapy in Individuals With Chronic Low Back Pain
Status: COMPLETED
Conditions: Chronic Low Back Pain
Interventions: OTHER: Manual Therapy|OTHER: Manual Therapy plus TECAR|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nigella 5 in the Treatment of SARS COV2 (COVID-19)
Status: COMPLETED
Conditions: SARS-CoV2 Infection
Interventions: DRUG: Nigella|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Do Generic Volar Locking Plates Provide Similar Outcomes at a Reduced Cost?
Status: COMPLETED
Conditions: Distal Radius Fractures
Interventions: DEVICE: Generic Volar Locking Plate|DEVICE: Conventional Volar Locking Plate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Heart Failure (HF) Outpatient Monitoring Evaluation (HOME) Study
Status: COMPLETED
Conditions: Heart Failure|Systolic Heart Failure|Acute Decompensated Heart Failure
Interventions: OTHER: Interventions with heart failure medications
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: The Effect of Oral Guaifenesin on Pediatric Chronic Rhinitis: A Pilot Study
Status: COMPLETED
Conditions: Chronic Rhinitis
Interventions: DRUG: Placebo|DRUG: Guaifenesin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Prospective, Comparative Study of Intravenous Iron Isomaltoside 1000 (Monofer®) Administered by Infusions to Non-Anaemic Patients Undergoing Elective or Sub-Acute Coronary Artery Bypass Graft, Valve Replacement or a Combination Thereof
Status: COMPLETED
Conditions: Non-anaemic Patients Undergoing Cardiac Surgery
Interventions: DRUG: Iron isomaltoside 1000 (Monofer®)|DRUG: Natriumklorid 9 mg/ml, Fresenius Kabi
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Designing Biofunctional Dairy Foods: Matrix Structure of Dairy Products in Relation to Lipaemia
Status: COMPLETED
Conditions: Lipaemia
Interventions: DIETARY_SUPPLEMENT: Cheddar cheese|DIETARY_SUPPLEMENT: Blended and homogenized cheddar cheese|DIETARY_SUPPLEMENT: An analog milk|DIETARY_SUPPLEMENT: An analog cheese
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: LNG-IUS at 2 Weeks Postpartum
Status: COMPLETED
Conditions: Contraception|Malposition of Intrauterine Contraceptive Device
Interventions: DRUG: Levonorgestrel Intrauterine System (LNG-IUS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Randomized Trial of 24-Week Versus 48-Week Courses of Peginterferon Plus Ribavirin for HCV Genotype-1 Patients
Status: COMPLETED
Conditions: Chronic Hepatitis C|Genotype
Interventions: DRUG: pegylated interferon alpha 2a and ribavirin|DRUG: Pegylated interferon alfa-2a and ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Tofacitinib vs Methotrexate on Rheumatoid Arthritis Interstitial Lung Disease
Status: TERMINATED
Conditions: Rheumatoid Arthritis|Interstitial Lung Disease Due to Systemic Disease (Disorder)|RA|ILD
Interventions: DRUG: Tofacitinib|DRUG: Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SOD1 Inhibition by Pyrimethamine in Familial Amyotrophic Lateral Sclerosis (ALS)
Status: COMPLETED
Conditions: Familial Amyotrophic Lateral Sclerosis
Interventions: DRUG: Pyrimethamine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Copenhagen Study of Obese Patients With Ischemic Heart Disease Undergoing Low Energy Diet or Interval Training
Status: COMPLETED
Conditions: Ischemic Heart Disease|Obesity
Interventions: OTHER: Interval Training|OTHER: Weight Loss
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effects of Omega-3 Fatty Acids in Renal Transplantation
Status: COMPLETED
Conditions: Disorder Related to Renal Transplantation
Interventions: DRUG: Omega-3 fatty acids|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Drug Persistence/Adherence in Patients Treated With Dabigatran or VKA for Stroke Prevention in Non Valvular Atrial Fibrillation (SPAF)
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DRUG: Dabigatran etexilate|DRUG: Vitamin K antagonists
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase IIIB/IV Study to Compare the Efficacy of Vancomycin Therapy to Extended Duration of Fidaxomicin Therapy in the Clinical Cure of Clostridium Difficile Infection (CDI) in an Older Population
Status: COMPLETED
Conditions: Clostridium Difficile
Interventions: DRUG: Fidaxomicin|DRUG: Vancomycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess Naporafenib (ERAS-254) Administered With Trametinib in Patients With NRAS-mutant Melanoma (SEACRAFT-2)
Status: RECRUITING
Conditions: Advanced or Metastatic NRAS-mutant Melanoma
Interventions: DRUG: Naporafenib|DRUG: Dacarbazine|DRUG: Temozolomide|DRUG: Trametinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stereotactic Radiosurgery vs Whole Brain Radiotherapy in Breast Cancer With Brain Oligometastasis
Status: RECRUITING
Conditions: Breast Cancer|Brain Metastases, Adult|Stereotactic Radiosurgery|Whole Brain Radiotherapy
Interventions: RADIATION: Stereotactic Radiosurgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Food-Specific and Component IgE Threshold Levels That Predict Food Allergy in People With Elevated Total Serum IgE Levels and Atopic Dermatitis
Status: RECRUITING
Conditions: Milk and/or Peanut Allergy
Interventions: OTHER: Peanut powder and Oat flour|OTHER: Peanut flour and Oat flour (placebo for peanut flour)|OTHER: Dry Milk Powder and Corn Starch (placebo for Milk powder)|OTHER: Baked milk and Rice milk (placebo for Baked milk)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Pilot Study: Safety of Chlorhexidine (CHG) Baths in Patients Less Than 2 Months of Age
Status: COMPLETED
Conditions: Chlorhexidine Allergy|Infection|Rash
Interventions: DRUG: Chlorhexidine gluconate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effect of Core Muscles Training On Patients With Chronic Mechanical Low Back Pain According To SALIBA'S Postural Classification System
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Low-back Pain
Interventions: OTHER: core muscles training exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of Two Probiotic Formulations on Mental Health and Mood Biomarkers in Adults With Depressive Symptoms
Status: COMPLETED
Conditions: Depression, Anxiety
Interventions: DIETARY_SUPPLEMENT: B. adolescentis Bif-038|DIETARY_SUPPLEMENT: Lacticaseibacillus rhamnosus, LGG® and Bifidobacterium, BB-12®|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Denosumab China Phase III Study
Status: COMPLETED
Conditions: Osteoporosis, Postmenopausal
Interventions: DRUG: Denosumab|DRUG: Placebo|DIETARY_SUPPLEMENT: Elemental Calcium|DIETARY_SUPPLEMENT: Vitamin D
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Mesenchymal Autologous Stem Cells as Regenerative Treatment for Multiple Sclerosis
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Sclerosis|Progressive Multiple Sclerosis
Interventions: OTHER: MSCs|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Efficacy, Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of a Single Dose of LEO 158968
Status: NOT_YET_RECRUITING
Conditions: Joint Pain|Gout Flares|Joint Inflammation
Interventions: DRUG: LEO 158968
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Clinical Efficacy of the Lingual Brackets and Labial Brackets in the Leveling Phase
Status: COMPLETED
Conditions: Irregular Teeth
Interventions: DEVICE: Lingual brackets|DEVICE: Labial brackets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Melatonin for Renal Protection in Patients Receiving Polymyxin B
Status: TERMINATED
Conditions: Acute Kidney Injury|Melatonin|Polymyxin B Adverse Reaction
Interventions: DRUG: Melatonin Pill|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: NuvaRing Versus Marvelon in the Coordination of In Vitro Fertilization Cycles
Status: TERMINATED
Conditions: Infertility
Interventions: DRUG: Contraceptives, Oral|DRUG: Contraceptive, Vaginal ring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: The COPACC Study: Utilization, Health and Economic Evaluation of a Community-Based Primary Care Geriatric Hub at Whampoa
Status: COMPLETED
Conditions: Delivery of Health Care|Health Services|Costs and Cost Analysis|Quality of Life
Interventions: OTHER: Patient-centred care home (PCMH)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Metabolic Characteristics of Brain Tumors Using Hyperpolarized Carbon-13 Magnetic Resonance Spectroscopic Imaging (MRSI)
Status: RECRUITING
Conditions: Brain Tumor Adult
Interventions: DRUG: Hyperpolarized 13C-Pyruvate|DRUG: Gadolinium
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Sodium Hypochlorite Pulpotomies in Primary Molars: Comparison With Conventional 20% Formocresol Pulpotomies
Status: UNKNOWN
Conditions: Dental Pulp Disease
Interventions: PROCEDURE: NaOCl pulpotomy|PROCEDURE: FC pulpotomy|DRUG: 2.5% NaOCl|DRUG: 20% Formocresol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Flutiform, Fluticasone and Seretide in Treatment of Moderate to Severe Asthma in Paediatric Patients
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Flutiform|DRUG: Seretide|DRUG: Flixotide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Ofatumomab in Combination With ICE-chemotherapy in Patients With Diffuse Large B-cell Lymphoma (DLBCL)
Status: COMPLETED
Conditions: Diffuse Large B-cell Lymphoma
Interventions: DRUG: O-ICE (ofatumumab, Ifosfamide, Carboplatin, Etoposide)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fludarabine, Busulfan, and Antilymphocyte Globulin Followed by Donor Stem Cell Transplant in Treating Older Patients With Hematological Cancer
Status: COMPLETED
Conditions: Chronic Myeloproliferative Disorders|Leukemia|Lymphoma|Multiple Myeloma and Plasma Cell Neoplasm|Myelodysplastic Syndromes|Myelodysplastic/Myeloproliferative Neoplasms
Interventions: BIOLOGICAL: therapeutic immune globulin|DRUG: busulfan|DRUG: fludarabine phosphate|PROCEDURE: allogeneic hematopoietic stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Developing and Implementing Asthma-Guidance and Prediction System (a-GPS) for Better Asthma Management
Status: COMPLETED
Conditions: Asthma
Interventions: OTHER: Usual care + a-GPS|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: School-located Influenza Vaccination Clinics for Adolescents
Status: COMPLETED
Conditions: Childhood Influenza Vaccination|School-located Influenza Vaccination
Interventions: OTHER: School-located Influenza Vaccination
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Evaluating the Efficacy of E-Cigarette Use for Smoking Cessation (E3) Trial
Status: COMPLETED
Conditions: Smoking Cessation
Interventions: OTHER: Nicotine E-Cigarette|OTHER: Non-Nicotine E-Cigarette|BEHAVIORAL: Counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I IGART Study Using Active Breathing Control and Simultaneous Boost for Patients With NSCLC
Status: WITHDRAWN
Conditions: Adenocarcinoma of the Lung|Large Cell Lung Cancer|Squamous Cell Lung Cancer|Stage IIA Non-small Cell Lung Cancer|Stage IIB Non-small Cell Lung Cancer|Stage IIIA Non-small Cell Lung Cancer|Stage IIIB Non-small Cell Lung Cancer
Interventions: DRUG: Paclitaxel|RADIATION: image-guided adaptive radiation therapy|DRUG: carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Paricalcitol Trial: Phase II, Open Label Clinical Trial of Paricalcitol in Combination With Gemcitabine/ Nab-Paclitaxel Therapy in Advanced Pancreatic Cancer
Status: COMPLETED
Conditions: Advanced Pancreatic Cancer
Interventions: DRUG: Paricalcitol|DRUG: Gemcitabine (GEM) and Nab-paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Ricovir® in Maintaining Durability of Viral Response in Chronic Hepatitis B Patients Who Have Been Treated With Viread® and Have Undetectable HBV DNA in Serum
Status: COMPLETED
Conditions: Chronic Hepatitis B Infection
Interventions: DRUG: Tenofovir disoproxil fumarate|OTHER: Historical Data
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study in Patients With Fabry Disease Who Are on Chronic Hemodialysis Therapy for Treatment of End-stage Renal Insufficiency.
Status: WITHDRAWN
Conditions: Fabry Disease
Interventions: DRUG: Fabrazyme (agalsidase beta)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT