pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Randomized Controlled Trial of Gemcitabine Combined With 125I Brachytherapy
Status: COMPLETED
Conditions: Locally Advanced Pancreatic Cancer
Interventions: DRUG: gemcitabine|OTHER: 125I brachytherapy PLUS gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study for Patients With Prostate Cancer to See Whether Delivering an Extra Dose of Radiation to Parts of the Body With More Cancer is Better Than Standard Treatment in Which the Same Dose of Radiation is Given Throughout the Prostate Gland
Status: COMPLETED
Conditions: Prostatic Neoplasms
Interventions: RADIATION: 11C-Choline
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Thrombolysis With Recombinant Non-immunogenic Staphylokinase vs Surgery in Patients With Acute Limb Ischemia FORAT Trial
Status: RECRUITING
Conditions: Acute Limb Ischemia
Interventions: DRUG: Recombinant non-immunogenic staphylokinase (Fortelyzin®)|PROCEDURE: surgical methods of treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Jump Start Plus COVID-19 Support
Status: ACTIVE_NOT_RECRUITING
Conditions: Mental Health Wellness 1
Interventions: BEHAVIORAL: Jump Start Plus COVID Support|BEHAVIORAL: Healthy Caregivers-Healthy Children (HC2)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Assessment of the SurroundScope in Urologic Surgical Procedures
Status: UNKNOWN
Conditions: Partial Nephrectomy|Nephrectomy|Laparoscopy
Interventions: DEVICE: SurroundScope|DEVICE: Standard Laparoscope
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of a 6% Hydroxyethyl Starch (HES) Solution Versus an Electrolyte Solution in Trauma Patients
Status: COMPLETED
Conditions: Hypovolemia Due to Acute Blood Loss
Interventions: DRUG: Volulyte 6%|DRUG: Ionolyte
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Robot-Assisted US-Based Vertebral Segmentation for Pedicle Screw Trajectory Identification
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: Robot-assisted US Scan of the vertebra L1 to S1|OTHER: Handheld US scan of the vertebra L1 to S1|RADIATION: ULD CT scan of the vertebra L1 to S1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: INSPIRE: A Multi-Cancer Early Detection Study
Status: NOT_YET_RECRUITING
Conditions: Lung Cancer|Gastric Cancer|Liver Cancer|Colorectal Cancer|Pancreatic Cancer|Esophageal Cancer|Breast Cancer|Cervical Cancer|Ovarian Cancer|Endometrial Cancer|Bladder Cancer|Prostate Cancer|Cholangiocarcinoma
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Bacterial Lysates on Respiratory Tract Microecology and Evaluation of the Efficacy of Prevention and Treatment of VAP
Status: UNKNOWN
Conditions: Ventilators, Mechanical
Interventions: DRUG: Bacterial Lysates|OTHER: normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bone Loss and Immune Reconstitution in HIV/AIDS (BLIR-HIV)
Status: COMPLETED
Conditions: HIV Infection|Bone Loss|Osteopenia|Osteoporosis
Interventions: DRUG: Zoledronic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Meditation and Controls and Subjects With Parkinson's Disease on Brain Activity Measured by fMRI With FDOPA
Status: NOT_YET_RECRUITING
Conditions: Parkinson Disease|Idiopathic Parkinson Disease
Interventions: DRUG: [F-18] Fluorodopa Positron Emission Tomography|BEHAVIORAL: OM Meditation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Research on the Clinical Effect of Xuefu Zhuyu Decoction in Treating Unstable Angina.
Status: UNKNOWN
Conditions: Unstable Angina
Interventions: DRUG: Anti-Platelet Drugs|DRUG: Lipid Regulating Drugs|DRUG: Coronary Vasodilator|DRUG: Xuefu Zhuyu Decoction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Metabolic and Hemodynamic Reserve in Pediatric SCA
Status: RECRUITING
Conditions: Child, Only|Brain Diseases|Sickle Cell Disease|Anemia, Sickle Cell
Interventions: DRUG: Carbon Dioxide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Galvanic Vestibular Stimulation as a Novel Treatment for Seasickness
Status: COMPLETED
Conditions: Motion Sickness|Seasickness|Habituation|Vestibular Time Constant
Interventions: PROCEDURE: GVS stimulation coupled with inverse phase rotatory chair stimulation at sinusoidal harmonic acceleration protocol|PROCEDURE: Sham procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Niraparib, Temozolomide and Atezolizumab in Treating Patients With Advanced Solid Tumors and Extensive-Stage Small Cell Lung Cancer With a Complete or Partial Response to Platinum-Based First-Line Chemotherapy
Status: RECRUITING
Conditions: Advanced Malignant Solid Neoplasm|Extensive Stage Lung Small Cell Carcinoma|Stage III Lung Cancer AJCC v8|Stage IIIA Lung Cancer AJCC v8|Stage IIIB Lung Cancer AJCC v8|Stage IIIC Lung Cancer AJCC v8|Stage IV Lung Cancer AJCC v8|Stage IVA Lung Cancer AJCC v8|Stage IVB Lung Cancer AJCC v8
Interventions: BIOLOGICAL: Atezolizumab|DRUG: Niraparib|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration|DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial Examining Effects of Monosodium Glutamate (MSG) on Irritable Bowel Syndrome (IBS) and Fibromyalgia (FM)
Status: COMPLETED
Conditions: Irritable Bowel Syndrome|Fibromyalgia
Interventions: OTHER: Glutamate additive-free diet|OTHER: Placebo diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Topography Versus Non-Topography-Guided PRK With CXL in Keratoconus
Status: UNKNOWN
Conditions: Keratoconus
Interventions: PROCEDURE: Photorefractive keratectomy in mile keratoconus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Balancing Everyday Life - A Lifestyle Intervention for People With Psychiatric Disorders
Status: COMPLETED
Conditions: Major Psychiatric Disorder
Interventions: BEHAVIORAL: Balancing Everyday Life (BEL)|BEHAVIORAL: Care as usual (generally standard occupational therapy)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Usability and Acceptability Study of the P-STEP Mobile Application
Status: RECRUITING
Conditions: Asthma|Chronic Obstructive Pulmonary Disease|Interstitial Lung Disease|Coronary Heart Disease|Heart Failure|Type 2 Diabetes
Interventions: OTHER: P-STEP Mobile Application
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical Trial of Lurbinectedin (PM01183) in Patients With Advanced Solid Tumors
Status: UNKNOWN
Conditions: Advanced Solid Tumors
Interventions: DRUG: Lurbinectedin alone|DRUG: Lurbinectedin+Itraconazole co-administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: LYT-100 in Post-acute COVID-19 Respiratory Disease
Status: TERMINATED
Conditions: Covid19|Post-acute COVID-19 Respiratory Disease
Interventions: DRUG: LYT-100|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dose Response to Topical Glyceryl Trinitrate in Patients With Raynaud's Phenomenon
Status: COMPLETED
Conditions: Raynaud's Phenomenon
Interventions: DRUG: placebo cream|DRUG: Glyceryl Trinitrate|DRUG: Glyceryl Trinitrate|DRUG: Glyceryl Trinitrate|DRUG: Glyceryl Trinitrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Empagliflozin (BI 10773) Dose Finder Study in Japanese Patients With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Placebo (low dose)|DRUG: Placebo (low dose)|DRUG: Placebo (mid dose)|DRUG: Placebo (high dose)|DRUG: BI 10773|DRUG: Placebo (mid dose)|DRUG: Placebo (high dose)|DRUG: Placebo (high dose)|DRUG: BI 10773|DRUG: BI 10773|DRUG: Placebo (mid dose)|DRUG: Placebo (high dose)|DRUG: Placebo (low dose)|DRUG: Placebo (low dose)|DRUG: BI 10773|DRUG: Placebo (mid dose)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Protein C Concentrate in Subjects With Severe Congenital Protein C Deficiency
Status: COMPLETED
Conditions: Protein C Deficiency
Interventions: DRUG: Protein C Concentrate (Human) Vapor Heated
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety of DTaP or DT Vaccine in 6 Year Old Children
Status: NOT_YET_RECRUITING
Conditions: Vaccine Reaction
Interventions: BIOLOGICAL: vaccinate with DTap|BIOLOGICAL: vaccinate with DT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Study to Evaluate Efficacy and Safety of MY-REPT Capsule in Primary, Liver Transplantation Recipients (MYLT1)
Status: UNKNOWN
Conditions: Evidence of Liver Transplantation
Interventions: DRUG: Mycophenolate mofetil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tacrolimus/Sirolimus/Methotrexate vs Tacrolimus/Methotrexate or Cyclosporine/Mycophenolate Mofetil for GVHD Prophylaxis After Reduced Intensity Allogeneic Stem Cell Transplantation for Patients With Lymphoma
Status: COMPLETED
Conditions: Non-hodgkin Lymphoma|Hodgkin Lymphoma
Interventions: DRUG: Sirolimus|DRUG: Methotrexate|DRUG: Tacrolimus|DRUG: Cyclosporine|DRUG: MMF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Computed Tomography and Biomarker Analysis in Diagnosing Coronary Artery Disease in Asymptomatic Patients Who Have Undergone Stem Cell Transplant
Status: COMPLETED
Conditions: Cancer Survivor|Diabetes Mellitus|Hypertension
Interventions: PROCEDURE: computed tomography|OTHER: cytology specimen collection procedure|OTHER: laboratory biomarker analysis|OTHER: questionnaire administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Could Peri-anal Block be Effective as Caudal Block in Trans-anal Pull-through Surgery ??.
Status: UNKNOWN
Conditions: Analgesia
Interventions: PROCEDURE: Peri-anal local anaesthetic infiltration|PROCEDURE: Caudal anaesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of Lumbopelvic Non-Thrust Spinal Manipulation on Individuals With Low Back Pain
Status: COMPLETED
Conditions: Low Back Pain
Interventions: OTHER: Lumbar Spine Manipulation|OTHER: Sham Manipulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effect of Famotidine and Omeprazole on MK0518 (Raltegravir) Pharmacokinetics in Human Immunodeficiency Virus (HIV)-Infected Patients (0518-054)
Status: COMPLETED
Conditions: HIV-1 Infection|HIV Infections
Interventions: DRUG: MK0518 (Raltegravir)|DRUG: famotidine|DRUG: omeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Warning Study of Serum Thioredoixn Reductase Activity in Excised Non-small Cell Lung Cancers (EWSOTRILC)
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer Stage I|Non-small Cell Lung Cancer Stage II|Non-small Cell Lung Cancer Stage IIIA
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Taxotere and Adriamycin/Cytoxan (AC) Validation in Breast Cancer Patients
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Taxotere/Docetaxel|DRUG: Adriamycin/Cytoxan|DRUG: doxorubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Necessity of Antibiotics for Prevention of Delivery-associated Infections After Spontaneous Vaginal Delivery at Term
Status: TERMINATED
Conditions: Perineal Wound Infection
Interventions: DRUG: Amoxicillin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Comparison of the Pharmacokinetics of Albumin-bound Docetaxel and Taxotere
Status: UNKNOWN
Conditions: Advanced Solid Tumors
Interventions: DRUG: Docetaxel for Injection (Albumin-bound)|DRUG: Taxotere
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Self - Adjustable Clavicular Brace Versus Standard Clavicular Brace for Treatment of Mid Shaft Clavicle Fracture: A Randomized Controlled Study
Status: RECRUITING
Conditions: Clavicle Fracture
Interventions: DEVICE: Clavicular brace
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Brace Versus Casting in Pediatric Radial Head Fractures
Status: UNKNOWN
Conditions: Radial Fracture
Interventions: DEVICE: elbow cast|DEVICE: Removable elbow brace
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Trial of Directly Observed Anti HCV Therapy & Contingency Management in a Population on Opiate Substitute Therapy
Status: COMPLETED
Conditions: Hepatitis C
Interventions: PROCEDURE: Assessment & Treatment of HCV infection with oral antivirals
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of the Soluble Mediators of Mastocytes on the Intestinal Epithelial Barrier and of the Enteric Nervous System During the Syndrome of the Irritable Bowel
Status: UNKNOWN
Conditions: Irritable Bowel Syndrome
Interventions: PROCEDURE: Colic biopsies
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Impact of a Focal Muscle Vibration Protocol in Front of the the Anterior Tibial Muscle in the Subacute Post-stroke Period on Motor Recovery in Hemiplegic Patients.
Status: COMPLETED
Conditions: Stroke
Interventions: OTHER: Fugl-Meyer Assessment (FMA)|OTHER: Medical Research Concil (MRC)|OTHER: 2 Minute Walk Test (2MWT)|OTHER: Timed Up & Go Test|OTHER: Modified Ashworth Scale|OTHER: Postural Assessment Scale for Stroke|DEVICE: posturographic recording|OTHER: vibration program|OTHER: sham program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Cognitive Remediation on Patients With Bipolar Disorder and Memory Complaints
Status: UNKNOWN
Conditions: Patient With Bipolar Disorder|Euthymic Status|Wirh Memory Complaints
Interventions: BEHAVIORAL: COGMED program
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: To Better Understand the Most Important Factors for Patients When They Decide on the Type of Treatment They Receive for Muscle Invasive Bladder Cancer (MIBC).
Status: RECRUITING
Conditions: Muscle Invasive Bladder Cancer|Surgery|Sexual Wellbeing|Patient Satisfaction|Patient Preference
Interventions: OTHER: Discrete Choice Experiment (DCE) Patients DCE Questionnaire|OTHER: Semi-Structured Interview Patients Interview
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of the Effectiveness and Safety of High Dose, Short-course Levofloxacin in the Treatment of Acute Bacterial Exacerbation (Worsening) of Chronic Bronchitis.
Status: COMPLETED
Conditions: Bronchitis|Chronic Bronchitis
Interventions: DRUG: levofloxacin, azithromycin, amoxicillin/clavulanate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Hypoxic Preconditioning on Patients
Status: COMPLETED
Conditions: Hypoxic Preconditioning|Carotid Artery Stenosis|Ischemic Cerebrovascular Disease
Interventions: PROCEDURE: Mild Hypoxia Preconditioning|PROCEDURE: Sham preconditioning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Tailored Therapeutic Model According to the Expression of Genes in Inflammatory Bowel Disease Patients
Status: COMPLETED
Conditions: Inflammatory Bowel Diseases
Interventions: GENETIC: genotyping for three genes (TPMT, NUDT15 and FTO)|OTHER: non-genotyping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Improvement of RARP Outcomes Via 3D Printed/Virtual Prostate Models
Status: NOT_YET_RECRUITING
Conditions: Prostate Cancer
Interventions: DEVICE: 3D Printed Models (3D printing facilities at GSTT)|DEVICE: 3D Virtual Models (Innersight Labs)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Preoperative Oral Midazolam to Postoperative Pain Relief in Sleep Disturbance or Anxiety Patients With Colorectal Cancer
Status: NOT_YET_RECRUITING
Conditions: Preoperative|Sleep Disturbance|Anxiety|Midazolam|Pain, Postoperative
Interventions: DRUG: Midazolam oral solution|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Prevention of Sacral Pressure Ulcers With Preventive Dressings
Status: COMPLETED
Conditions: Grade I to Grade IV Pressure Ulcers in Higher Risk Patients
Interventions: DEVICE: Mepilex® Border Sacrum dressings
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Fermented Soybean Supplementation Among Active Pulmonary Tuberculosis Patients With Standard Therapy in Indonesia
Status: COMPLETED
Conditions: Pulmonary Tuberculosis|Body Weight Changes|Motor Activity
Interventions: DRUG: Rifampicin|DRUG: Isoniazid|DRUG: Pyrazinamide|DRUG: Ethambutol|DIETARY_SUPPLEMENT: Fermented soybean
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Acceptance and Commitment Therapy for Patients Undergoing Coronary Artery Bypass Graft Surgery
Status: RECRUITING
Conditions: Coronary Artery Disease|Vascularization
Interventions: BEHAVIORAL: Acceptance and commitment therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: CD8 DLI for Patients With Relapse or Residual Disease Following Allogeneic Stem Cell Transplantation
Status: TERMINATED
Conditions: Chronic Myelogenous Leukemia|Multiple Myeloma|Non Hodgkin's Lymphoma|Hodgkin's Disease|Chronic Lymphocytic Leukemia
Interventions: BIOLOGICAL: CD8 Depleted Donor Lymphocyte
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and PK/PD Study in Young Adult Patients With Childhood Onset Growth Hormone Deficiency (GHD).
Status: COMPLETED
Conditions: Growth Hormone Deficiency
Interventions: DRUG: ARX201|DRUG: ARX201|DRUG: ARX201
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Dose-Finding Study to Evaluate Ovarian Function and Vaginal Bleeding in Next Generation Rings (P06109/MK-8175A/MK-8342B-012)
Status: COMPLETED
Conditions: Contraception
Interventions: DRUG: Nomegestrol acetate (NOMAC)|DRUG: Etonogestrel (ENG)|DRUG: Ethinyl estradiol (EE)|DRUG: Estradiol (E2)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study Comparing ProDisc-C to ACDF Surgery to Treat SCDD
Status: COMPLETED
Conditions: Symptomatic Cervical Disc Disease
Interventions: DEVICE: Total Disc Replacement|DEVICE: ACDF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: BE Study of the Combinations of Gemigliptin 50mg and Metformin HCl Extended Release 2000mg in Comparison to Each Component Administered Alone
Status: UNKNOWN
Conditions: Healthy
Interventions: DRUG: gemigliptin and metformin HCl extended release|DRUG: gemigliptin/metformin HCl extended release
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oxytocin and Fetal Heart Rate Changes
Status: RECRUITING
Conditions: Fetal Bradycardia Complicating Labor and Delivery|Fetal Bradycardia During Labor|Fetal Heart Rate or Rhythm Abnormality Affecting Fetus
Interventions: DRUG: Half dose Oxytocin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Safety, Tolerability and Efficacy Study With QBW251 in COPD Patients With QBW251
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease, COPD
Interventions: DRUG: QBW251|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acute Medically Ill VTE Prevention With Extended Duration Betrixaban Study (The APEX Study)
Status: COMPLETED
Conditions: Venous Thromboembolism (VTE)
Interventions: DRUG: Betrixaban|DRUG: Enoxaparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Double-blind, Placebo-controlled, Randomized Study of the Tolerability, Safety and Immunogenicity of an Inactivated Whole Virion Concentrated Purified Vaccine (CoviVac) Against Covid-19 of Children at the Age of 12-17 Years Inclusive"
Status: ACTIVE_NOT_RECRUITING
Conditions: Vaccine
Interventions: BIOLOGICAL: Vaccine for intramuscular injection|OTHER: Placebo comparator (without active ingredient) for intramuscular injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Safety, Pharmacodynamics, Pharmacokinetics, and Efficacy of Tomivosertib Combined With Paclitaxel in Advanced Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: tomivosertib|DRUG: paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Targeting Adolescent Insomnia to Lessen Overall Risk of Suicidal Behavior
Status: RECRUITING
Conditions: Insomnia|Suicidal Ideation|Suicide, Attempted
Interventions: BEHAVIORAL: TAILOR|OTHER: Enhanced Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Compliance With Once-Daily Divalproex Extended-Release Tablets (Depakote-ER) Versus Multiple-Daily Dose Valproic Acid Capsules (Depakene) in Epilepsy:
Status: COMPLETED
Conditions: Epilepsy
Interventions: BEHAVIORAL: Compliance
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: CSL312 (Garadacimab) in the Prevention of Hereditary Angioedema Attacks
Status: COMPLETED
Conditions: Hereditary Angioedema
Interventions: BIOLOGICAL: CSL312|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation Of Bilateral Tecnis Multifocal Versus ReSTOR 3D Intraocular Lenses
Status: COMPLETED
Conditions: Cataract
Interventions: DEVICE: Tecnis MF|DEVICE: ReSTOR
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Breast Cancer Chemoprevention by SOM230, an IGF-I Action Inhibitor
Status: TERMINATED
Conditions: Ductal Carcinoma in Situ
Interventions: DRUG: SOM 230 / Pasireotide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Robotic Exoskeleton Gait Training in Adolescents With Cerebral Palsy
Status: RECRUITING
Conditions: Cerebral Palsy
Interventions: BEHAVIORAL: Robotic Exoskeleton Gait Therapy|BEHAVIORAL: Physical Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of The Effect of RoActemra/Actemra (Tocilizumab) in Combination With Methotrexate on Articular Damage in The Hand in Patients With Moderate to Severe Rheumatoid Arthritis Who Have an Inadequate Response to Non-Biological DMARDs
Status: WITHDRAWN
Conditions: Rheumatoid Arthritis
Interventions: DRUG: methotrexate|DRUG: tocilizumab [RoActemra/Actemra]
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Estradiol as add-on to Antipsychotics
Status: UNKNOWN
Conditions: Schizophrenia|Schizoaffective Disorder|Schizophreniform Disorders
Interventions: DRUG: Estradiol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of ALKS 3831 in Subjects With Schizophrenia and Alcohol Use Disorder
Status: COMPLETED
Conditions: Schizophrenia|Alcohol Use Disorder
Interventions: DRUG: Samidorphan + olanzapine (ALKS 3831)|DRUG: Placebo + olanzapine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized, Open-label Phase 2 Study of Oral AZD0914 in the Treatment of Gonorrhea
Status: COMPLETED
Conditions: Gonorrhoea
Interventions: DRUG: AZD0914|DRUG: Ceftriaxone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: Clinical- and Immunological Activity, Safety and Tolerability of Different Doses / Formulations of AFFITOPE AD02 in Early Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: BIOLOGICAL: active: AFFITOPE AD02|BIOLOGICAL: control: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Healing Effects Of Honey and Hydrogel Products On The Diabetic Foot
Status: COMPLETED
Conditions: Diabetic Foot
Interventions: DRUG: Medihoney Gel in A Tube|DRUG: Hydrogel|DRUG: Fucidin Ointment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study of Mattress Type in Fibromyalgia
Status: COMPLETED
Conditions: Fibromyalgia
Interventions: OTHER: Tempur-Pedic Mattress (2 months)|OTHER: Control Mattress (2 months)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Scaling and Root Planing (SRP) With PerioWave vs. SRP Alone in Chronic Periodontitis
Status: COMPLETED
Conditions: Periodontitis
Interventions: DEVICE: PerioWave|PROCEDURE: Scaling and Root Planing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Valganciclovir in Prevention of Cytomegalovirus (CMV) Reactivation Following Allogeneic-Stem Cell Transplantation (SCT)
Status: COMPLETED
Conditions: Bone Marrow Transplantation|Cytomegalovirus
Interventions: DRUG: Valganciclovir|DRUG: Acyclovir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: L-ArGinine to pRevent advErse prEgnancy Outcomes (AGREE)
Status: NOT_YET_RECRUITING
Conditions: Pregnancy|Malaria|Nutrition|Placental Development|Preterm Birth|Fetal Growth Restriction
Interventions: DIETARY_SUPPLEMENT: L-citrulline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Clinical, Radiographic and Patient Acceptance Evaluation of LASER Compared to Formocresol Pulpotomies inPrimary Molars
Status: COMPLETED
Conditions: Pulpitis Reversible
Interventions: PROCEDURE: Diode laser|PROCEDURE: Er:CrYSGG|PROCEDURE: Formocresol
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Glenoid Position Using SmartBones
Status: COMPLETED
Conditions: Anatomic Total Shoulder Arthroplasty
Interventions: DEVICE: DePuy Global® Anchor Peg Glenoid Instrumentation|DEVICE: DePuy Global® Anchor Peg Instrumentation with SmartBone™|DEVICE: IRI with SmartBone™|DEVICE: RTI with SmartBone™|DEVICE: IRI with SmartBase
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Flow Diverter Technology Device for Intracranial Aneurysm
Status: RECRUITING
Conditions: Intracranial Aneurysms
Interventions: DEVICE: Pipeline™ Flex Embolization Device with Shield Technology™
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: PTH Comparison in Post Menopausal Women
Status: COMPLETED
Conditions: Osteoporosis, Post-Menopausal
Interventions: DRUG: teriparatide 20 micrograms/day subcutaneous|DRUG: calcitonin 100 IU/day subcutaneous
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral Appliances With and Without Elastic Bands to Treat Obstructive Sleep Apnea: A Randomized Crossover Trial
Status: COMPLETED
Conditions: Sleep Apnea, Obstructive
Interventions: DEVICE: Oral appliance with elastic bands|DEVICE: Oral appliance without elastic bands
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transplantation of Autologous Oral Mucosal Epithelial Sheets for Limbal Stem-cell Deficiency
Status: COMPLETED
Conditions: Limbal Stem-cell Deficiency
Interventions: BIOLOGICAL: Mucosal cell sheet transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ketosis-Prone Diabetes Mellitus (KPDM): Metformin Versus Sitagliptin Treatment
Status: COMPLETED
Conditions: Ketosis Prone Diabetes|Diabetes Ketoacidosis|Hyperglycemia
Interventions: DRUG: metformin|DRUG: placebo|DRUG: Sitagliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Different Duration of Bolloon Dilation During ESBD
Status: UNKNOWN
Conditions: Common Bile Duct Stones
Interventions: PROCEDURE: 30" group|PROCEDURE: 60" group|PROCEDURE: 180" group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: IAH0968 in Combination With GC for the Treatment of HER2-Positive Unresectable Advanced/Metastatic Malignant Tumors
Status: RECRUITING
Conditions: HER2 Gene Mutation
Interventions: COMBINATION_PRODUCT: Injection of IAH0968+Gemcitabine+Cisplatin|COMBINATION_PRODUCT: Gemcitabine+Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Can Applying the Science of Habit Formation to Contemplative Practice Improve Outcomes
Status: ACTIVE_NOT_RECRUITING
Conditions: Psychopathology
Interventions: BEHAVIORAL: Self-Compassionate Touch Intervention|BEHAVIORAL: Habit Formation Tools
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Assess Influence of MyCyFAPP Use on GI Related QOL in Children With Cystic Fibrosis
Status: UNKNOWN
Conditions: Cystic Fibrosis in Children
Interventions: DEVICE: MyCyFAPP
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Calcium and Vitamin D, With and Without Collagen Peptide, in Enhancing Bone Mineral Density on Postmenopausal Women With Osteopenia
Status: COMPLETED
Conditions: Osteopenia
Interventions: DRUG: Fortibone|DRUG: Chewable Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Relative Bioavailability of Linaprazan for the Test Formulation vs. Reference Formulation
Status: COMPLETED
Conditions: Safety|Bioavailability|Pharmacokinetics
Interventions: DRUG: Linaprazan glurate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study to Evaluate the Efficacy of Acarbose,Metformin,Sitagliptin Combination Treatment in DM Patients
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Acarbose|DRUG: Placebo acarbose|DRUG: placebo metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cemented vs. Non-Cemented TSA for OA of the Shoulder
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: PROCEDURE: Cemented Humeral Stem|PROCEDURE: Uncemented Humeral Stem
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: The Effect of EDP on Diaphragmatic Function and Neural Respiratory Drive in Patient With AECOPD
Status: COMPLETED
Conditions: Acute Exacerbation of Chronic Obstructive Pulmonary Disease
Interventions: DEVICE: control group|DEVICE: EDP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Higher Doses of Botulinum Toxin in the Treatment of Gummy Smile
Status: COMPLETED
Conditions: Smiling|Botulinum Toxins, Type A
Interventions: DRUG: injection of Botulinum type A
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study of VG2025 Delivered Intraperitoneally in Patients With Advanced Solid Tumors With Carcinomatosis
Status: NOT_YET_RECRUITING
Conditions: Advanced Solid Tumor|Carcinomatosis
Interventions: DRUG: VG2025
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: DAHANCA 25A: Resistance Training and Dietary Supplements as Intervention for Regaining Muscle Mass Following Radiotherapy in Head and Neck Cancer Patients
Status: COMPLETED
Conditions: Head and Neck Neoplasms
Interventions: OTHER: Resistance training|DIETARY_SUPPLEMENT: Protein and creatine|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Prevention of POV After Paediatric Tonsillectomy
Status: COMPLETED
Conditions: Vomiting
Interventions: DRUG: Dexamethasone|DEVICE: Acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Red Light Photobiomodulation and Topical Disinfectants
Status: COMPLETED
Conditions: Healthcare Associated Infection|Nosocomial Infection|Surgical Site Infection
Interventions: DEVICE: Methylene Blue Only|DEVICE: Chlorhexidine Gluconate Only|DEVICE: Methylene Blue + Chlorhexidine Gluconate|DEVICE: Light Only
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effectiveness of the Ivivi Torino II, Pulsed Radio Frequency Device, on Narcotic Use, Pain and Quality of Life Following Shoulder Arthroscopic Rotator Cuff Repair.
Status: TERMINATED
Conditions: Rotator Cuff Tear
Interventions: DEVICE: Ivivi Torino II|DEVICE: Inactive Sham device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Improving Post COVID-19 Syndrome With Hyperbaric Oxygen Treatments
Status: RECRUITING
Conditions: Post COVID-19 Condition|Post-COVID-19 Syndrome|Post-COVID Syndrome|COVID-19|Fatigue|Fatigue Syndrome, Chronic
Interventions: DEVICE: Monoplace Hyperbaric Chamber (Class III medical device).
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: BRAF/MEK/EGFR Inhibitor Combination Study in Colorectal Cancer (CRC)
Status: COMPLETED
Conditions: Cancer
Interventions: DRUG: Dabrafenib|DRUG: Trametinib|DRUG: Panitumumab|DEVICE: 5-fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical and Metagenomic Investigation of Antimicrobial Peptide Gel in Periodontal Treatment.
Status: COMPLETED
Conditions: Periodontitis
Interventions: DRUG: 0.85% synthetic antimicrobial peptide TAPS-18|DRUG: 0.9% normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Supplementing Intracytoplasmic Sperm Injection Handling Medium With Latrunculin A (ICSI-LA)
Status: COMPLETED
Conditions: Infertility
Interventions: OTHER: Medium Supplemented with Latrunculin A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Phase 1b/2 Study of Futibatinib in Combination With Binimetinib in Patients With Advanced KRAS Mutant Cancer
Status: TERMINATED
Conditions: Advanced or Metastatic Solid Tumors Irrespective of Gene Alterations|Non-Small Cell Lung Cancer|KRAS Gene Mutation
Interventions: DRUG: Futibatinib and Binimetinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison in New Cochlear Implanted Subjects of a Tonotopy-based Fitting With or Without Fine Structure Coding
Status: RECRUITING
Conditions: Sensorineural Hearing Loss, Bilateral
Interventions: DEVICE: TnoFs then TFS (Cochlear implant)|DEVICE: TFS then TnoFS (Cochlear implant)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Cognitive and Cerebral Blood Flow Effects of Vitamin C
Status: COMPLETED
Conditions: Endothelial Function|Cognition
Interventions: DIETARY_SUPPLEMENT: Vitamin C
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Low Dose Bismuth Versus Lactobacillus Reuteri for H. Pylori Eradication
Status: TERMINATED
Conditions: Helicobacter Pylori Infection
Interventions: DRUG: Bismuth Subcitrate Potassium|DIETARY_SUPPLEMENT: Gastrus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Irinotecan, Levofolinate, and 5-Fluorouracil (FOLFIRI) Plus Ramucirumab (IMC-1121B)
Status: COMPLETED
Conditions: Colorectal Carcinoma
Interventions: BIOLOGICAL: Ramucirumab (IMC-1121B)|DRUG: Irinotecan|DRUG: levofolinate|DRUG: 5-Fluorouracil (5-FU)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Aronia Berry Consumption on Inflammation, Metabolites, and the Gut Microbiome
Status: COMPLETED
Conditions: Inflammation|Metabolic Disorder|Hypertriglyceridemia
Interventions: DIETARY_SUPPLEMENT: Aronia juice|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Low-pressure Pulmonary Recruitment Maneuver to Decrease Post-laparoscopic Shoulder Pain in Gynecologic Surgery
Status: COMPLETED
Conditions: Gynecologic Disease|Laparoscopic Surgery
Interventions: PROCEDURE: Pulmonary recruitment maneuver
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Study of NNZ-2566 in Patients With Traumatic Brain Injury
Status: COMPLETED
Conditions: Brain Injuries
Interventions: DRUG: NNZ-2566|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Transdermal Optical Imaging (TOI) as a Non-invasive Measure to Detect Changes in Hydration Status in Healthy Adults and Athletes
Status: RECRUITING
Conditions: Dehydration
Interventions: OTHER: GENPOP ad libitum fluid intake|OTHER: GENPOP fluid restriction|OTHER: ATHLETE ad libitum fluid intake|OTHER: ATHLETE restricted fluid intake
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effects of Aplindore on the Treatment of Signs and Symptoms of Restless Legs Syndrome
Status: COMPLETED
Conditions: Restless Legs Syndrome
Interventions: DRUG: Aplindore|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Biomarkers as Predictors of Suicidal Risk in Adolescents
Status: COMPLETED
Conditions: Suicide, Attempted|Suicidal Ideation|Suicidal Intention|Suicide
Interventions: OTHER: Clinical assessments and blood samples; follow-up for 12 mos|OTHER: Clinical assessments and blood samples; no 12mo follow-up
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Assessment of an Integrated Continuous Glucose Monitor and Insulin Injection Port in Type 2 Diabetes
Status: NOT_YET_RECRUITING
Conditions: Type 2 Diabetes Treated With Insulin
Interventions: DEVICE: Use of novel insulin injection port
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Conservative Treatment by Nocturnal Wrist Orthosis in the Non-surgical Management of Carpal Tunnel Syndrome (AMYLYONCARP)
Status: RECRUITING
Conditions: Carpal Tunnel Syndrome
Interventions: DEVICE: Nocturnal wrist orthosis wearing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Crenolanib With Ramucirumab and Paclitaxel for Advanced Esophagogastric Adenocarcinoma
Status: COMPLETED
Conditions: Esophagogastric Adenocarcinoma
Interventions: DRUG: Crenolanib|DRUG: Ramucirumab|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial Comparing the Efficacy and Safety of Open Dressing With Petrolatum Jelly vs. Standard Gauze Dressing With Silver Sulfadiazine
Status: COMPLETED
Conditions: Superficial Partial Thickness Burns
Interventions: DRUG: Open Dressings with Petrolatum Jelly|DRUG: Silver Sulfadiazine Gauze Dressing Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT