pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Botanical Therapy in Treating Mucositis in Patients With Head and Neck Cancer Who Have Undergone Chemoradiation Therapy
Status: WITHDRAWN
Conditions: Mucositis|Recurrent Squamous Cell Carcinoma of the Hypopharynx|Recurrent Squamous Cell Carcinoma of the Larynx|Recurrent Squamous Cell Carcinoma of the Lip and Oral Cavity|Recurrent Squamous Cell Carcinoma of the Nasopharynx|Recurrent Squamous Cell Carcinoma of the Oropharynx|Recurrent Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity|Recurrent Verrucous Carcinoma of the Larynx|Recurrent Verrucous Carcinoma of the Oral Cavity|Stage III Squamous Cell Carcinoma of the Hypopharynx|Stage III Squamous Cell Carcinoma of the Larynx|Stage III Squamous Cell Carcinoma of the Lip and Oral Cavity|Stage III Squamous Cell Carcinoma of the Nasopharynx|Stage III Squamous Cell Carcinoma of the Oropharynx|Stage III Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity|Stage III Verrucous Carcinoma of the Larynx|Stage III Verrucous Carcinoma of the Oral Cavity|Stage IV Squamous Cell Carcinoma of the Hypopharynx|Stage IV Squamous Cell Carcinoma of the Nasopharynx|Stage IVA Squamous Cell Carcinoma of the Larynx|Stage IVA Squamous Cell Carcinoma of the Lip and Oral Cavity|Stage IVA Squamous Cell Carcinoma of the Oropharynx|Stage IVA Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity|Stage IVA Verrucous Carcinoma of the Larynx|Stage IVA Verrucous Carcinoma of the Oral Cavity|Stage IVB Squamous Cell Carcinoma of the Larynx|Stage IVB Squamous Cell Carcinoma of the Lip and Oral Cavity|Stage IVB Squamous Cell Carcinoma of the Oropharynx|Stage IVB Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity|Stage IVB Verrucous Carcinoma of the Larynx|Stage IVB Verrucous Carcinoma of the Oral Cavity|Tongue Cancer
Interventions: OTHER: placebo|PROCEDURE: quality-of-life assessment|OTHER: questionnaire administration|DRUG: Vaccinium myrtillus/Macleaya cordata/Echinacea angustifolia extract granules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy of a Spirulina Supplement for Amelioration of Benign ThYroid Nodules
Status: COMPLETED
Conditions: Benign Thyroid Nodule
Interventions: DIETARY_SUPPLEMENT: Preparation with Spirulina|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Inspiratory Muscle Training on Respiratory Muscle Function，Quality of Life and Exercise Capacity in Stable COPD
Status: COMPLETED
Conditions: COPD
Interventions: DEVICE: Threshold inspiratory muscle training|DEVICE: Resistive inspiratory muscle training|OTHER: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Motor Learning on a Sequence of Manual Motor Gestures of Increasing Complexity Through the Mental Practise
Status: UNKNOWN
Conditions: Motor Activity
Interventions: BEHAVIORAL: Motor imagery|BEHAVIORAL: Action observation|BEHAVIORAL: Placebo intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy of INM004 in Children With STEC-HUS
Status: RECRUITING
Conditions: Hemolytic-Uremic Syndrome
Interventions: BIOLOGICAL: INM004|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lumbar Spine Muscle Degeneration Inhibits Rehabilitation-Induced Muscle Recovery
Status: COMPLETED
Conditions: Disc Degeneration|Low Back Pain
Interventions: OTHER: Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect of Simulation-based Breastfeeding Education on Breastfeeding Self-efficacy and Breastfeeding Problems
Status: ENROLLING_BY_INVITATION
Conditions: Postpartum Complication|Caesarean Section;Stillbirth
Interventions: DEVICE: simulation implication
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pembrolizumab And Tamoxifen Among Women With Advanced Hormone Receptor Positive Breast Cancer And Esr1 Mutation
Status: UNKNOWN
Conditions: Breast Cancer Female
Interventions: DRUG: Pembrolizumab + Tamoxifen
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TOward the Lowest Effective DOse of Abatacept or Tocilizumab
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Tocilizumab, Abatacept|DRUG: Decrease Tocilizumab, Abatacept
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Yoga and Relaxation on Stress and Quality of Life
Status: COMPLETED
Conditions: Stress, Psychological
Interventions: BEHAVIORAL: Integrative Yoga|BEHAVIORAL: Iyengar Yoga|BEHAVIORAL: Mindfulness
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of CPAP on Cardiovascular Risk in Obstructive Sleep Apnea (OSA) and Metabolic Syndrome
Status: COMPLETED
Conditions: Obstructive Sleep Apnea|Metabolic Syndrome
Interventions: DEVICE: CPAP device - REMstar Plus, Respironics, Murrysville, USA
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Opioid Use Disorder Treatment Linkage at Sexual Health Clinics Using Buprenorphine
Status: ENROLLING_BY_INVITATION
Conditions: Opioid-use Disorder
Interventions: BEHAVIORAL: Patient Navigation|DRUG: Buprenorphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Comparison of Combination Chemotherapy Regimens With or Without Cetuximab in Treating Patients Who Have Undergone Surgery For Stage III Colon Cancer
Status: COMPLETED
Conditions: Adenocarcinoma of the Colon|Stage III Colon Cancer
Interventions: DRUG: irinotecan hydrochloride|DRUG: oxaliplatin|DRUG: leucovorin calcium|DRUG: fluorouracil|BIOLOGICAL: cetuximab|DRUG: Locally Directed Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Safety and Efficacy of IPN10200 in Adult Participants With Upper Limb Spasticity.
Status: ACTIVE_NOT_RECRUITING
Conditions: Spasticity
Interventions: BIOLOGICAL: IPN10200|DRUG: Placebo|BIOLOGICAL: Dysport
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effect of Lorcaserin Hydrochloride on Smoking Cessation
Status: COMPLETED
Conditions: Smoking Cessation
Interventions: DRUG: APD356-lorcaserin hydrochloride|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: TicagRelor Or Clopidogrel in Severe and Terminal Chronic Kidney Disease Patients Undergoing PERcutaneous Coronary Intervention for an Acute Coronary Syndrome.
Status: UNKNOWN
Conditions: Acute Coronary Syndrome
Interventions: DRUG: Clopidogrel|DRUG: Ticagrelor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Thermic & Lipemic Properties of Dietary Carbohydrates
Status: COMPLETED
Conditions: Exogenous Obesity|Dietary Modification
Interventions: OTHER: High Glycemic Index meals|OTHER: Low Glycemic Index meals
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Morphological and Functional Evaluation of Irvine-Gass Syndrome
Status: COMPLETED
Conditions: Irvine Gass Syndrome
Interventions: BEHAVIORAL: if needed (decided individually) either Acular eye drops, Ultracortenol eye drop or intravitreal triamcinolone injection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: MAGENTUM 1 HeartMate 3 LVAS: A Single Center Prospective Controlled Study (MAGENTUM 1)
Status: UNKNOWN
Conditions: Heart Failure|Cardiovascular Diseases
Interventions: DRUG: Warfarin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radical Fimbriectomy for Young BRCA Mutation Carriers
Status: ACTIVE_NOT_RECRUITING
Conditions: BRCA1 Mutation|BRCA2 Mutation|Hereditary Breast and Ovarian Cancer
Interventions: PROCEDURE: Radical fimbriectomy|OTHER: Histopathology SEE-FIM
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparative Efficacy, Safety and Immunogenicity Study of Etanercept and Enbrel
Status: UNKNOWN
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Etanercept|DRUG: Enbrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combined Fractional CO2 Laser With Topical Tioconazole Versus Q-switched Nd:YAG Laser in the Treatment of Onychomycosis; a Randomized Controlled Trial
Status: RECRUITING
Conditions: Onychomycosis of Fingernail
Interventions: DRUG: Topical tioconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of BMS-512148 (Dapagliflozin) in Patients With Type 2 Diabetes and Inadequately Controlled Hypertension on an Angiotensin-Converting Enzyme Inhibitor or Angiotensin Receptor Blocker
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: Dapagliflozin|DRUG: Placebo-matching dapagliflozin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: CP101 for the Treatment of Ulcerative Colitis
Status: RECRUITING
Conditions: Ulcerative Colitis
Interventions: DRUG: CP-101|DRUG: CP-101 + Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Self-management Program for Patients in the Sub-acute Phase After Traumatic Injury - a Feasibility Study
Status: COMPLETED
Conditions: Self-management|Feasibility Studies|Spinal Cord Injuries|Brain Injuries
Interventions: BEHAVIORAL: self-management program after traumatic injuries
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Efficacy Study of a TXA127 to Reduce Acute Graft-vs-Host Disease in Subjects Undergoing Double Umbilical Cord Blood Transplantation
Status: WITHDRAWN
Conditions: Hematologic Malignancies
Interventions: DRUG: TXA127
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phase III Study of S-1 + Cisplatin vs Cisplatin in Cervical Cancer
Status: COMPLETED
Conditions: Cervical Cancer
Interventions: DRUG: S-1 + Cisplatin (arm A)|DRUG: Cisplatin (arm B)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating Changes in Spermatogram Following Bilateral Laparoscopic Inguinal Hernia Repair in Fertile Males
Status: TERMINATED
Conditions: Hernia
Interventions: PROCEDURE: laparoscopic bilateral hernia repair
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Acute Alcohol Response In Bipolar Disorder: a Longitudinal Alcohol Administration/fMRI Study
Status: RECRUITING
Conditions: Bipolar Disorder|Alcohol Drinking|Alcohol Use Disorder
Interventions: OTHER: Alcohol vs. Placebo beverage conditions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Impact of ERAS Program in Cardiac Surgery on Patient Prognosis
Status: RECRUITING
Conditions: ERAS
Interventions: OTHER: Nutrition|OTHER: Control Blood Glucose|DRUG: Fasting|BEHAVIORAL: Smoking and Alcohol|OTHER: Control Anemia|OTHER: Blood Transfusion|OTHER: GDFT|OTHER: Remove the tracheal tube|BEHAVIORAL: Eating and Drinking|OTHER: Prevent Thrombosis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Food-Based Recommendations for Minangkabau Women of Reproductive Age With Dyslipidemia
Status: COMPLETED
Conditions: Dietary Habits|Nutrient Deficiency|Obesity|Dyslipidemias
Interventions: BEHAVIORAL: Promotion of Food-based recommendations|BEHAVIORAL: Nutrition counseling from standard health services care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Telemonitoring to Treat Group 2 Pulmonary Hypertension
Status: WITHDRAWN
Conditions: Pulmonary Hypertension Due to Left Heart Disease
Interventions: DRUG: Treprostinil Diolamine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Natural Progesterone and Vaginal Pessary for the Prevention of Spontaneous Preterm Birth
Status: UNKNOWN
Conditions: Preterm Labor|Premature Birth
Interventions: DRUG: natural progesterone|DEVICE: cervical pessary
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigate Effect of Secukinumab on the PK of Midazolam in Patients With Mod to Sev Plaque Psoriasis
Status: COMPLETED
Conditions: Moderate to Severe Plaque Psoriasis
Interventions: DRUG: Midazolam|DRUG: AIN457
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of 1 Month vs. 12 Months DAPT in Patients Undergoing PCI With Genoss® DES
Status: RECRUITING
Conditions: Coronary Artery Disease
Interventions: DRUG: 1 Month vs. 12 Months DAPT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Role of the Nasal Allergen Provocation Test in Starting and Monitoring Allergen Immunotherapy
Status: RECRUITING
Conditions: Perennial Allergic Rhinitis|Seasonal Allergic Rhinitis|Local Allergic Rhinitis
Interventions: DRUG: AIT|DIAGNOSTIC_TEST: NAPT
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Deep Brain Stimulation to Treat Symptoms of Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson Disease|Movement Disorders
Interventions: DEVICE: Libra Deep Brain Stimulation System|DEVICE: Libra Deep Brain Stimulation System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Rocking Bed on Preterm Newborns
Status: COMPLETED
Conditions: Preterm|Preterm Birth|Nurse's Role
Interventions: BEHAVIORAL: rocking bed group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effectiveness of Multiple Micro-nutrient Fortified Fudge on Nutritional Status of 3-5 Years of Age Children
Status: UNKNOWN
Conditions: Micronutrient Deficiencies|Anemia|Fortification|Undernutrition|Early Childhood Development
Interventions: DIETARY_SUPPLEMENT: Placebo|BEHAVIORAL: Formative messgaes|DIETARY_SUPPLEMENT: Fortified product|COMBINATION_PRODUCT: Fortified product plus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: APART: Prevention and Automatic Therapy of Atrial Arrhythmias in Patients With Paroxysmal Supraventricular Tachycardias
Status: COMPLETED
Conditions: Tachyarrhythmia
Interventions: DEVICE: Activation of preventive and therapeutic algorithms for treatment of AF|DEVICE: AF Prevention and Therapy Algorithms On
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Discussing Death and Dying: An End of Life Curriculum to Empower Residents
Status: COMPLETED
Conditions: Education, Medical|Education, Medical, Graduate|Care, Palliative|Medicine, Palliative
Interventions: BEHAVIORAL: Facilitated Group Session|BEHAVIORAL: CELA Session
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Effect of Different Physiotherapeutic Stimuli on Stomatognathic System Structures.
Status: UNKNOWN
Conditions: Pain|Stomatognathic Diseases|Muscle Hypertonia|Myofacial Pain Syndromes|Analgesia|Musculoskeletal Pain|Craniomandibular Osteopathy|Temporomandibular Disorder
Interventions: OTHER: Four different physiotherapy treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Randomized Control Trial to Study the Efficacy of the Surgical Mask Versus the N95 Respirator to Prevent Influenza
Status: COMPLETED
Conditions: Influenza
Interventions: DEVICE: Surgical mask|DEVICE: N95 mask
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Novel Multi-factorial Criteria-based Rehabilitation Program for Chronic Mid-portion Achilles Tendinopathy
Status: COMPLETED
Conditions: Achilles Tendinopathy
Interventions: OTHER: Exercise therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: REperfusion Facilitated by LOcal Adjunctive Therapy in ST-elevation Myocardial Infarction
Status: COMPLETED
Conditions: ST-elevation Myocardial Infarction (STEMI)
Interventions: DRUG: IC Adenosine|DRUG: IC Sodium nitroprusside (SNP)|PROCEDURE: Standard PCI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: An Interaction Study to Assess Drug Levels in Fasting Healthy Adult Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Raltegravir|DRUG: Fosamprenavir|DRUG: Ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose:
Clinical trial: A Phase 2 Dose Escalating Study to Evaluate the Safety and Efficacy of CB-03-01 Cream in Subjects With Facial Acne Vulgaris
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: CB-03-01|DRUG: Vehicle|DRUG: CB-03-01
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing the Effects of Ondansetron Versus Dexamethasone on the Incidence of Post-dural Puncture Headache (PDPH) , Nausea and Vomiting After Spinal Anaesthesia of Parturients Undergoing Caesarean Section
Status: UNKNOWN
Conditions: Post-Dural Puncture Headache
Interventions: DRUG: Intravenous drug
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Immediate Stiffness Changes in Myofascial Trigger Points After Dry Needling
Status: COMPLETED
Conditions: Myofascial Pain Syndrome|Neck Pain|Trigger Point Pain, Myofascial
Interventions: OTHER: Dry Needling|OTHER: Sham Dry Needling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Improvement of the Operative Outcome in Patients With Primary VEGF + Unifocal Breast Cancer or DCIS Through the Intraoperative Visualization of the Tumor Using Molecular Imaging and Bevacizumab-IRDye-800CW
Status: WITHDRAWN
Conditions: Breast Cancer
Interventions: DRUG: Bevacizumab-IRDye800CW
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intravenous Lidocaine Randomized Comparative Effectiveness Trial
Status: COMPLETED
Conditions: Abdominal Pain
Interventions: DRUG: Hydromorphone|DRUG: Lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Antimicrobial Treatment of Acute Otitis Media on the Intestinal Microbiome in Children
Status: COMPLETED
Conditions: Acute Otitis Media
Interventions: DRUG: Amoxicillin|DRUG: Amoxicillin-Potassium Clavulanate|DRUG: Macrolide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Efficacy and Safety Study of CC-5013 Monotherapy in Subjects With Myelodysplastic Syndromes
Status: COMPLETED
Conditions: Myelodysplastic Syndromes
Interventions: DRUG: CC-5013
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Registry of IgA Nephropathy in Chinese Children
Status: RECRUITING
Conditions: IgA Nephropathy|Proteinuria in Nephrotic Range|Immunosuppressive Treatment
Interventions: DRUG: Corticosteroid|DRUG: Cyclophosphamide|DRUG: Mycophenolate mofetil|DRUG: Dipyridamole|DRUG: ACE Inhibitor or Angiotensin receptor antagonist
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of High Ventilation Breathwork With Retention (HVBR) on Health
Status: COMPLETED
Conditions: Stress|Anxiety|Depressive Symptoms|Mental Wellbeing|Positive Affect|Negative Affect|Sleep-Related Impairment
Interventions: BEHAVIORAL: High ventilation breathwork with retention (HVBR)|BEHAVIORAL: Placebo HVBR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Single and Multiple Ascending Dose Study of LTG-305 Administered Orally in Healthy Participants
Status: NOT_YET_RECRUITING
Conditions: Healthy
Interventions: DRUG: LTG-305
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Safety and Efficacy of Oral Encapsulated Fecal Microbiota Transplant in Peanut Allergic Patients
Status: COMPLETED
Conditions: Peanut Allergy
Interventions: BIOLOGICAL: Fecal Microbiota Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non Invasive Evaluation of Bronchial Inflammation in Infants : a Study of the Sputum Cellularity After Hypertonic Saline Induction
Status: TERMINATED
Conditions: Infantile Asthma
Interventions: OTHER: Sputum induction
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: A Phase II Study of Oral LDE225 in Patients With Hedge-Hog (Hh)-Pathway Activated Relapsed Medulloblastoma (MB)
Status: COMPLETED
Conditions: Medulloblastoma
Interventions: DRUG: LDE225|DRUG: TMZ
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of 20vPnC Coadministered With SIIV in Adults ≥65 Years of Age
Status: COMPLETED
Conditions: Pneumococcal Disease
Interventions: BIOLOGICAL: Experimental 20-valent pneumococcal conjugate vaccine (20vPnC)|OTHER: Saline|BIOLOGICAL: Influenza vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Open-label, Single-arm, Proof of Concept Study in Subjects With Mild-to-moderate Facial Hyperpigmentation
Status: NOT_YET_RECRUITING
Conditions: Facial Hyperpigmentation
Interventions: DRUG: Test cosmetic product
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Inhaled CMS in Bronchiectasis Subjects With Chronic P. Aeruginosa Infection. (PROMIS-I)
Status: COMPLETED
Conditions: Non Cystic Fibrosis Bronchiectasis
Interventions: DRUG: CMS|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Homoharringtonine and Interferon Alfa in Treating Patients With Chronic Myelogenous Leukemia
Status: COMPLETED
Conditions: Leukemia
Interventions: BIOLOGICAL: recombinant interferon alfa|DRUG: omacetaxine mepesuccinate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Will Perceptual Learning Via Video Game Playing Improve Visual Acuity Stereopsis & Fixation Stability in Mild Amblyopes?
Status: COMPLETED
Conditions: Amblyopia
Interventions: DEVICE: Dichoptic video game in an i-Pod touch device|DEVICE: Video game in an i-Pod touch device
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aripiprazole to Reduce Cocaine Relapse
Status: COMPLETED
Conditions: Cocaine-Related Disorders
Interventions: DRUG: Aripiprazole|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment Of Stromal Response To Nab-Paclitaxel In Combination With Gemcitabine In Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DRUG: Gemcitabine plus nab-paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Fecal Microbiota Transplantation (FMT) in Pediatric Functional Gastrointestinal Disorders
Status: RECRUITING
Conditions: Functional Gastrointestinal Disorders
Interventions: BIOLOGICAL: FMT|DRUG: Conventional drugs
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Sleep Interventions for Posttraumatic Stress Disorder (PTSD)
Status: COMPLETED
Conditions: Anxiety Disorders|Mood Disorders|Insomnia|Nightmares
Interventions: BEHAVIORAL: Behavioral Sleep Intervention|DRUG: Prazosin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Is Neutrophil to Lymphocyte Ratio a Prognostic Factor of Sepsis in Newborns With Operated Neural Tube Defects?
Status: COMPLETED
Conditions: Neural Tube Defects|Newborn Sepsis
Interventions: DIAGNOSTIC_TEST: Neutrophil to lymphocyte ratio
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of the Relationship Between Sleep Quality and Daytime-Nighttime Variations of Blood Pressure and Plasma Glucose Type I
Status: TERMINATED
Conditions: Type 1 Diabetes
Interventions: BIOLOGICAL: Biological examinations (blood and urinary).
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Skin Blood Flow Changes Using Laser Doppler Imager for Assessment of Pain and Analgesia in Newborn Infants
Status: COMPLETED
Conditions: Procedural Pain
Interventions: DRUG: sucrose 24% oral solution|DRUG: sterile water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: High Energy Density Pulse Electromagnetic Field for Patients With Frozen Shoulder
Status: RECRUITING
Conditions: Frozen Shoulder
Interventions: DEVICE: High energy density pulse electromagnetic field|OTHER: physiotherapy|DEVICE: sham High energy density pulse electromagnetic field
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase Three Clinical Trials of Trivalent Rotavirus Genetic Reassortment Vaccine
Status: UNKNOWN
Conditions: Randomized|Double-blind|Placebo Control Design
Interventions: BIOLOGICAL: trivalent rotavirus genetic reassortment vaccine|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Combination Chemotherapy in Treating Patients With Locally Advanced or Metastatic Solid Tumors
Status: COMPLETED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: alvocidib|DRUG: irinotecan hydrochloride|DRUG: fluorouracil|DRUG: leucovorin calcium|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose-finding Study of GLPG0634 as add-on to Methotrexate in Active Rheumatoid Arthritis Participants (DARWIN1)
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: GLPG0634|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Development & Testing of a Decision Aid for LVAD Placement
Status: COMPLETED
Conditions: End-Stage Heart Failure|Bridge-to-Transplant LVAD Placement (BTT)|Destination Therapy LVAD Placement (DT)|Refusal of LVAD Placement (Decliners)|LVAD Caregivers
Interventions: OTHER: LVAD Decision Aid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Outpatient Use of Ivermectin in COVID-19
Status: WITHDRAWN
Conditions: Covid19
Interventions: DRUG: Ivermectin Pill|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare SB17 (Proposed Ustekinumab Biosimilar) to European Union (EU) Sourced Stelara and United States of America (US) Sourced Stelara in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Ustekinumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Randomized Trial of Vaccine Adherence in Young Injection Drug Users
Status: COMPLETED
Conditions: Medication Adherence|Substance Abuse, Intravenous|Risk Behavior|Hepatitis A|Hepatitis B|Hepatitis C
Interventions: BIOLOGICAL: Hepatitis A & B vaccine|BEHAVIORAL: Outreach|BEHAVIORAL: AIC|BEHAVIORAL: SEP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety Study of of Intravenous CCL2-LPM in Patients With IgA Nephropathy
Status: TERMINATED
Conditions: IGA Nephropathy|Proteinuria
Interventions: BIOLOGICAL: OPL-CCL2-LPM
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: KN026 in Patients With HER2 Expressing Gastric/Gastroesophageal Junction Cancer
Status: COMPLETED
Conditions: Gastric/Gastroesophageal Junction Cancer
Interventions: DRUG: KN026 10 mg/kg QW|DRUG: KN026 20 mg/kg Q2W|DRUG: KN026 30 mg/kg Q3W
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Outpatient Digital Follow-up of Patients Over 70 Years of Age Undergoing Chemotherapy Treatment
Status: UNKNOWN
Conditions: Breast Cancer|Colorectal Cancer|Lung Cancer
Interventions: DEVICE: IPC NET
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Home-based Interventions for FrAilty preveNTion in AdultS With DIabeTes and Chronic Kidney Disease
Status: RECRUITING
Conditions: Diabetes Type 2|Frailty|Kidney Diseases
Interventions: OTHER: Resistance Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Full Spectrum vs. Standard Forward-viewing Colonoscopy
Status: COMPLETED
Conditions: Colon Neoplasms
Interventions: PROCEDURE: standard forward-viewing colonoscopy|PROCEDURE: full-spectrum colonoscopy|PROCEDURE: right colon retroflexion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Choline Supplementation as a Neurodevelopmental Intervention in Fetal Alcohol Spectrum Disorders Study
Status: RECRUITING
Conditions: Fetal Alcohol Spectrum Disorders
Interventions: DRUG: Choline Bitartrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: DEB-TACE Combined With Apatinib and PD-1 for the Treatment of Intrahepatic Cholangiocarcinoma
Status: RECRUITING
Conditions: Intrahepatic Cholangiocarcinoma|Transarterial Chemoembolization|Apatinib|PD-1 Antibody
Interventions: COMBINATION_PRODUCT: DEB-TACE combined with apatinib and PD-1 antibody
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Corticosteroid Prophylaxis on the Cardiopulmonary Bypass-Induced Systemic Inflammatory Response
Status: COMPLETED
Conditions: Heart Valve Diseases|Systemic Inflammatory Response Syndrome
Interventions: DRUG: Corticosteroid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of Specific Allergen Immunotherapy in Grass Pollen Allergic Subjects With Epicutanoeus Allergen Administration
Status: COMPLETED
Conditions: Allergic Rhinoconjunctivitis
Interventions: DRUG: Patch|DRUG: Placebo patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Immunogenicity, Safety and Reactogenicity of FluBlok, To a Licensed Vaccine In Elderly Adults
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Influenza Vaccination
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: An mHealth Intervention for Sedentary Behavior in Pregnant Women
Status: COMPLETED
Conditions: Pregnancy Related|Sedentary Behavior
Interventions: BEHAVIORAL: NEAT!2 sedentary behavior app|OTHER: Pregnancy smartphone app
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Safety & Biological Activity of IP IMNN-001 (Also Known as GEN-1) With Neoadjuvant Chemo in Ovarian Cancer
Status: COMPLETED
Conditions: Epithelial Ovarian Cancer|Fallopian Tube Cancer|Primary Peritoneal Cancer
Interventions: BIOLOGICAL: IMNN-001
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Irinotecan and Cisplatin in Treating Patients Who Are Undergoing Surgery For Locally Advanced Cancer of the Stomach or Gastroesophageal Junction
Status: COMPLETED
Conditions: Gastric Adenocarcinoma|Stage II Gastric Cancer|Stage III Gastric Cancer|Stage IV Gastric Cancer
Interventions: DRUG: Cisplatin|PROCEDURE: Computed Tomography|RADIATION: Fludeoxyglucose F-18|OTHER: Fluorothymidine F-18|DRUG: Irinotecan Hydrochloride|PROCEDURE: Positron Emission Tomography|PROCEDURE: Therapeutic Conventional Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics Study of CJ-30060 After Single Dose Administration in Health Male Volunteers
Status: COMPLETED
Conditions: Hypertension|Hyperlipidemias
Interventions: DRUG: CJ-30060|DRUG: Exforge tab 5/160mg, Crestor tab 10mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optic Nerve Sheath Diameter in Pre-Eclamptic Parturient Receiving Magnesium Sulfate Combined With Dexmedetomidine
Status: RECRUITING
Conditions: Preeclampsia Severe|Optic Nerve Sheath Diameter
Interventions: DRUG: Dexmedetomidine|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: T21,18 and 13 Screening by Cell Free Fetal DNA in Low Risk Patients
Status: COMPLETED
Conditions: Trisomy 21, 18 and 13 Screening
Interventions: DEVICE: Genetic NIPT|BIOLOGICAL: Regular serum screening
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Resuscitative Endocrinology:Single-dose Clinical Uses for Estrogen-Traumatic Brain Injury
Status: COMPLETED
Conditions: Traumatic Brain Injury
Interventions: DRUG: Premarin IV|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Colchicine to Decrease Atrial Fibrillation Recurrence After Ablation
Status: RECRUITING
Conditions: Atrial Fibrillation
Interventions: DRUG: Colchicine 0.6 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Parmigiano Reggiano on Skeletal Muscle Damage in Older Adults
Status: UNKNOWN
Conditions: Old Age; Atrophy|Inflammatory Response|Muscle Soreness
Interventions: DIETARY_SUPPLEMENT: Parmigiano Reggiano|DIETARY_SUPPLEMENT: Whey Protein
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Two Regimens of Anti-VEGF Therapy in Chinese Patients With Polypoidal Choroidal Vasculopathy
Status: UNKNOWN
Conditions: Polypoidal Choroidal Vasculopathy
Interventions: PROCEDURE: OCTA plus OCT guided 3+PRN regimen|PROCEDURE: OCT guided 3+PRN regimen|DRUG: Anti-VEGF drug
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Epidural Analgesia in Different Cervix Diameter and the Rate of Cesarean Delivery
Status: COMPLETED
Conditions: Labor Pain
Interventions: PROCEDURE: Epidural labor analgesia|PROCEDURE: Epidural labor analgesia|PROCEDURE: Epidural labor analgesia|PROCEDURE: Epidural labor analgesia|PROCEDURE: Epidural labor analgesia|PROCEDURE: Epidural labor analgesia|PROCEDURE: Epidural labor analgesia|PROCEDURE: Epidural labor analgesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of PBM on Fixed-appliance Orthodontic Patients
Status: RECRUITING
Conditions: Orthodontics|Root Resorption
Interventions: DEVICE: photobiomodulation therapy|OTHER: orthodontic fixed-appliance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Longitudinal Cohort Study Comparing 2 Surgical Techniques in Patients With Class 3 Obesity and Type 2 Diabetes
Status: COMPLETED
Conditions: Obesity|Type 2 Diabetes
Interventions: PROCEDURE: Roux-en-Y gastric bypass|PROCEDURE: Adjustable gastric band
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: 'In Situ Simulation' Versus 'Off Site Simulation' in Obstetric Emergencies
Status: COMPLETED
Conditions: Education|Obstetrics|Simulation|'In Situ Simulation'
Interventions: OTHER: In situ simulation|OTHER: Off site simulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Sirolimus, Tacrolimus and Short Course Methotrexate for Prevention of Acute GVHD in Recipients of Mismatched Unrelated Donor Allogeneic Stem Cell Transplantation
Status: COMPLETED
Conditions: Stem Cell Transplantation
Interventions: DRUG: tacrolimus|DRUG: Sirolimus|DRUG: Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose Escalating Study of a Prototype CS6 Subunit Vaccine With a Modified Heat-labile Enterotoxin From Enterotoxigenic Escherichia Coli (ETEC)
Status: COMPLETED
Conditions: Diarrhea
Interventions: BIOLOGICAL: CssBA|BIOLOGICAL: dmLT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Intervention in Minimizing Aflatoxins and Fumonisins Exposure to Children Through Food and Breastfeeding in Tanzania
Status: COMPLETED
Conditions: Growth Retardation
Interventions: BEHAVIORAL: post-harvest intervention package|BEHAVIORAL: Routine agriculture extension services
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Return to Work Rehabilitation
Status: UNKNOWN
Conditions: Sick Leave|Occupational Health
Interventions: BEHAVIORAL: long rehabilitation program|BEHAVIORAL: short rehabilitation program|BEHAVIORAL: Acceptance and commitment therapy (ACT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Central Venous Catheter Colonisation Among Critically Ill Patients in Intensive Care Units
Status: COMPLETED
Conditions: Sepsis|Septic Shock|Post-cardiac Surgery|Post-Cardiorespiratory Arrest Coma|Head Injury|Hypoxic Brain Damage|Acute Liver Failure|Diabetic Ketoacidotic Hyperglycaemic Coma
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study to Explore the Effect of Lowering Blood Viscosity in Patients With Treatment-resistant Critical Limb Ischemia
Status: COMPLETED
Conditions: Critical Limb Ischemia
Interventions: PROCEDURE: phlebotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Allogenic AD-MSC Transplantation in Idiopathic Nephrotic Syndrome (Focal Segmental Glomerulosclerosis)
Status: UNKNOWN
Conditions: Focal Segmental Glomerulosclerosis
Interventions: BIOLOGICAL: Intravenous injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Teriparatide (Forteo) in the Treatment of Patients With Postoperative Hypocalcemia
Status: TERMINATED
Conditions: Hypocalcemia
Interventions: DRUG: Teriparatide (Forteo)|DRUG: Calcium|DRUG: Calcitriol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HepNet Pilot Trial: Multicenter Trial for the Treatment of Chronic Hepatitis E With Sofosbuvir (SofE)
Status: COMPLETED
Conditions: Hepatitis E|Hepatitis Chronic Viral
Interventions: DRUG: Sofosbuvir
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preventing Weight Gain and Controlling Blood Pressure During Smoking Cessation in Hypertensive Smokers
Status: COMPLETED
Conditions: Cardiovascular Diseases|Heart Diseases|Hypertension
Interventions: DRUG: Nicotine Replacement Therapy|BEHAVIORAL: Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Guiding Significance of Pupil Monitoring in the Perioperative Period
Status: COMPLETED
Conditions: Pupil Diameter|Pupil Contraction Rate|Pupil Light Reflection
Interventions: PROCEDURE: pupil's light and pupil diameter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Studying the Effect of Capsinoids on Brown Fat Using Infrared Thermal Imaging.
Status: COMPLETED
Conditions: Obesity|Diabetes|Impaired Glucose Tolerance
Interventions: DIETARY_SUPPLEMENT: Capsinoid/placebo and rice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: A Placebo-Controlled Adaptive Treatment Assignment Study of Intravenous COL-144 in the Acute Treatment of Migraine
Status: COMPLETED
Conditions: Migraine
Interventions: DRUG: Lasmiditan|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT