pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Bromocriptine and Pentoxifylline in Ophthalmopathy Autoimmune Treatment
Status: TERMINATED
Conditions: Graves Ophthalmopathy
Interventions: DRUG: Methimazole|DRUG: Bromocriptine|DRUG: Pentoxifylline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Abbott Atrial Fibrillation Post Approval Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Atrial Arrhythmia|Atrium; Fibrillation|Atrial Tachycardia
Interventions: DEVICE: electrophysiology study and ablation with an Abbott Ablation Catheter
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pharmacokinetic and Safety Study of Niraparib With Normal or Moderate Hepatic Impairment Patients
Status: COMPLETED
Conditions: Ovarian Neoplasms|Neoplasms|Solid Tumor|Hepatic Impairment
Interventions: DRUG: Niraparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Oleogel-S10 in Wound Healing of Split-Thickness Skin Graft Donor Sites (BSG-12)
Status: COMPLETED
Conditions: Wounds
Interventions: DRUG: Oleogel-S10, non-adhesive wound dressing|DEVICE: Non-adhesive wound dressing only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Double-Blinded, Placebo-Controlled Phase 1b Study for Safety, PK, Efficacy, PD of RO7049665 in Participants With Ulcerative Colitis (UC)
Status: TERMINATED
Conditions: Ulcerative Colitis
Interventions: DRUG: RO7049665|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare Two Techniques for Articular Cartilage Repair:ACIC Vs. MCIC
Status: UNKNOWN
Conditions: Articular Cartilage Defect
Interventions: PROCEDURE: ACIC|PROCEDURE: MCIC|DEVICE: implant with a collagen + fibrin gel mixture
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Massive Transfusion in Children-2: A Trial Examining Life Threatening Hemorrhage in Children
Status: NOT_YET_RECRUITING
Conditions: Hemorrhagic Shock|Trauma Injury
Interventions: BIOLOGICAL: Low Titer Group O Whole Blood (LTOWB)|DRUG: Placebo|DRUG: Tranexamic Acid (TXA)|BIOLOGICAL: Component Therapy (CT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Biomarkers for Predicting the Response to Inhaled Corticosteroid in Patients With Chronic Cough.
Status: NOT_YET_RECRUITING
Conditions: Cough
Interventions: DRUG: Beclometasone Dipropionate and Formoterol Inhalation Aerosol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Phase 2 Study of Temozolomide in Pre-Selected Advanced Aerodigestive Tract Cancers (Study P04273AM2)(TERMINATED)
Status: TERMINATED
Conditions: Colorectal Neoplasm|Head and Neck Neoplasm|Carcinoma, Non-Small-Cell Lung|Esophageal Neoplasm
Interventions: DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Potassium Nitrate in Reducing Dentinal Hypersensitivity
Status: COMPLETED
Conditions: Dentinal Hypersensitivity|Dental Pain
Interventions: DRUG: Potassium Nitrate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of a Tailored Program of Physical Activity and Nutritional Counseling on Fatigue Reduction in Breast Cancer Patients Receiving an Adjuvant Treatment
Status: COMPLETED
Conditions: Breast Cancer
Interventions: BEHAVIORAL: Tailored program of PA and nutritional counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of Different Approaches for Supraclavicular Block and Their Effects on Diaphragm Muscle Function
Status: COMPLETED
Conditions: Phrenic Nerve Paralysis|Diaphragm Sellae Meningioma|Complications|Respiratory Complication|Nerve Block|Brachial Plexus Block
Interventions: DRUG: Bupivacaine HCl 0.5% Injectable Solution|DRUG: Prilocaine HCl % 2 injectable solution|DRUG: adrenaline amp 0.5mg|PROCEDURE: Ultrasound Guided Supraclavicular Block Corner pocket approach|PROCEDURE: Ultrasound Guided Supraclavicular Block Corner pocket + intracluster approach|PROCEDURE: Ultrasound Guided Supraclavicular Block multi approach|PROCEDURE: diagraphma muscle evaluation with ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Effect of Food and a Proton Pump Inhibitor (PPI; Omeprazole) on LOXO-305 in Healthy Participants
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: LOXO-305|DRUG: Omeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Clinical Comparison of Two Soft Contact Lenses
Status: COMPLETED
Conditions: Myopia|Hyperopia
Interventions: DEVICE: Lens 1 (monthly replacement)|DEVICE: Lens 2 (daily disposable)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Lenalidomide and Dexamethasone With or Without Anakinra in Treating Patients With Early Stage Multiple Myeloma
Status: COMPLETED
Conditions: Indolent Plasma Cell Myeloma|Plasma Cell Myeloma|Smoldering Plasma Cell Myeloma
Interventions: BIOLOGICAL: Anakinra|DRUG: Dexamethasone|OTHER: Laboratory Biomarker Analysis|DRUG: Lenalidomide|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Thalidomide in Treating Anemia in Patients With Myelodysplastic Syndrome
Status: COMPLETED
Conditions: Leukemia|Myelodysplastic Syndromes|Myelodysplastic/Myeloproliferative Neoplasms
Interventions: DRUG: thalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Effect of Topical Tranexamic Acid on Postoperative Drainage in Minimally Invasive Transforaminal Lumbar Interbody Fusion (MI-TLIF)
Status: NOT_YET_RECRUITING
Conditions: Degenerative Spine Diseases|Surgical Wound
Interventions: DRUG: Tranexamic acid|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lessening Organ Dysfunction With VITamin C - COVID-19
Status: COMPLETED
Conditions: Vitamin C|COVID-19|Hospitalized Patients
Interventions: DRUG: Vitamin C|DRUG: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Preimplantation Genetic Diagnosis Using Blastocyst Biopsy and Array CGH
Status: SUSPENDED
Conditions: Infertility|Recurrent Pregnancy Loss
Interventions: GENETIC: PGD|PROCEDURE: PGD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Enteral Nutrition Support in Children and Adolescents With Cancer
Status: COMPLETED
Conditions: Malnutrition|Cancer
Interventions: DIETARY_SUPPLEMENT: industrialized oral supplementation (IOS) and tube feeding regimen (TFR) with Nutren
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Irreversible Electroporation Ablation for Colorectal Metastases to the Lung
Status: COMPLETED
Conditions: Colorectal Metastases to the Lung
Interventions: DEVICE: Irreversible Electroporation Ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral Propanolol for Surgically Inaccessible Cavernous Malformations
Status: UNKNOWN
Conditions: Cavernous Malformations,Cerebral and/or Spinal
Interventions: DRUG: Propranolol Oral Tablet|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability of Dalfampridine in Subjects With Cerebral Palsy
Status: COMPLETED
Conditions: Cerebral Palsy (CP)
Interventions: DRUG: dalfampridine-ER 10mg|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Non-invasive Neurostimulation as a Tool for Diagnostics and Management for Neurodegenerative Diseases
Status: RECRUITING
Conditions: Alzheimer Disease|Frontotemporal Dementia|Dementia With Lewy Bodies
Interventions: DEVICE: Gamma tACS (40 Hz) over the superior parietal cortex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Improving Psychological Wellbeing by Stress Reduction Among Parents Having Children With Neurodevelopmental Disorders
Status: NOT_YET_RECRUITING
Conditions: Mental Health Issue
Interventions: BEHAVIORAL: Parent's Emotional Intelligence Network|DEVICE: Diary|DEVICE: Mobile App
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Binge Eating Anxiety and Mood
Status: COMPLETED
Conditions: Binge-Eating Disorder|Binge Eating|Anxiety Disorders|Mood Disorders
Interventions: BEHAVIORAL: Executive Function- Enhanced CBT for BED (EF-BED+CBT)|BEHAVIORAL: Cognitive Behavioral Therapy (CBT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Compare Furmonertinib to Platinum-Based Chemotherapy for Patients With Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC) With Epidermal Growth Factor Receptor (EGFR) Exon 20 Insertion Mutations (FURVENT)
Status: RECRUITING
Conditions: Metastatic Non-Small Cell Lung Cancer|Advanced Non-Small Cell Lung Cancer|EGFR Exon 20 Mutations
Interventions: DRUG: furmonertinib 240 mg oral, daily|DRUG: furmonertinib 160 mg oral, daily|DRUG: platinum-based chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Short-Foot Exercises for Pes Planovalgus
Status: NOT_YET_RECRUITING
Conditions: Pes Planus
Interventions: OTHER: Intrinsic and Ectrinsic Exercise|OTHER: Intrinsic Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Impact of Oral Contrast in Multidetector CT of the Abdomen and Pelvis on Radiologist Confidence
Status: UNKNOWN
Conditions: Routine Outpatients Undergoing Contrast Enhanced CT Scan of the Abdomen and Pelvis
Interventions: OTHER: Withhold oral contrast
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Open-Labeled Study of PSI-7977 and RBV With and Without PEG-IFN in Treatment-Naïve Patients With HCV GT2 or GT3
Status: COMPLETED
Conditions: Chronic Hepatitis C Infection
Interventions: DRUG: SOF|DRUG: RBV|DRUG: PEG|DRUG: LDV|DRUG: GS-9669|DRUG: LDV/SOF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neural Respiratory Drive of Patients With Chronic Obstructive Pulmonary Disease
Status: RECRUITING
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: compound ipratropium bromide solution (3mg salbutamol and 500μg ipratropium, Boehringer Ingelheim Limited, Germany)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Interferon Alpha Therapy for Cervical CINI and HPV Infection
Status: RECRUITING
Conditions: Cervical Dysplasia|HPV Infection
Interventions: DRUG: gel Interferon arm|DRUG: gel Interferon and interferon suppository arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Effect of Lyophilized Cornus Mas L. on Anthropometric and Biochemical Parameters in Metabolic Associated Fatty Liver Disease Patients
Status: COMPLETED
Conditions: Fatty Liver Disease|Obesity|Liver Fat
Interventions: BEHAVIORAL: Diet|DIETARY_SUPPLEMENT: Cornus mas L.(Cornelian Cherry)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Efficacy and Safety of Vismed Gel Multi 0.3% Versus Vismed Multi 0.18% on Treatment of Ocular Dryness
Status: UNKNOWN
Conditions: Dry Eye
Interventions: DEVICE: Vismed gel Multi 0.3% eye drops|DEVICE: Vismed Multi 0.18% eye drops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Preoperative iLux on Cataract Surgery Derived Dry Eye Disease Due to Meibomian Gland Dysfunction
Status: RECRUITING
Conditions: Dry Eye Disease|Meibomian Gland Dysfunction|Cataract Senile|Dry Eye Syndromes
Interventions: DEVICE: Systane iLux Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity of a Live Attenuated Chimeric JE Vaccine (IMOJEV) as a Booster Dose in Thai Children Primed With CD.JEVAX
Status: COMPLETED
Conditions: Encephalitis
Interventions: BIOLOGICAL: Live attenuated chimeric Japanese Encephalitis vaccine|BIOLOGICAL: Inactivated Hepatitis A vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy Study of Polydioxanone (PDS) Plates in Rhinoplasty
Status: COMPLETED
Conditions: Rhinoplasty
Interventions: DEVICE: Polydioxanone (PDS) plates|PROCEDURE: Caudal septal extension graft performed through endonasal rhinoplasty|PROCEDURE: Caudal septal extension graft performed through endonasal rhinoplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Intragastric Administration of Fatty Acids on Generalized Reward Sensitivity
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DIETARY_SUPPLEMENT: dodecanoic acid|DIETARY_SUPPLEMENT: saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study to Assess Adverse Events and How ABBV-932 Oral Capsules Moves Through the Body of Healthy Adult Participants
Status: COMPLETED
Conditions: Generalized Anxiety Disorder (GAD)|Healthy Participants
Interventions: DRUG: ABBV-932|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Complicated Infections in Otorhinolaryngology
Status: NOT_YET_RECRUITING
Conditions: Sinusitis|Otitis|Laryngitis|Lymphadenitis|Quinsy|Peritonsillar Abscess|Parapharyngeal Abscess|Preseptal Cellulitis|Subperiosteal Abscess|Orbital Abscess|Epiglottitis
Interventions: OTHER: Treatment with surgery and/or conservative measures
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Bioavailability of 5 mg of Levamlodipine Maleate Tablets Versus 10 mg of Amlodipine Besylate Tablet in Healthy Subjects
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Levamlodipine, Amlodipine|DRUG: Amlodipine, Levamlodipine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and PK of Imeglimin in Japanese Volunteers
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Imeglimin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I Clinical Trial of ManNAc in Patients With GNE Myopathy or Hereditary Inclusion Body Myopathy (HIBM)
Status: COMPLETED
Conditions: Hereditary Inclusion Body Myopathy (HIBM)|GNE Myopathy
Interventions: DRUG: ManNAc
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Association of Transcutaneous Electrical Nerve Stimulation and Hypnosis
Status: COMPLETED
Conditions: Limbs Arthrosis|Non Arthrosic Limbs Arthralgia|Chronic Lomboradiculalgia|Chronic Back Pain|Cervical Radiculopathy|Post-herpetic Neuralgia|Post-surgical Peripheral Neuropathic Pain|Post Trauma Neuropathic Pain|Complex Regional Pain Syndrome Type I or II|Tendinopathy
Interventions: BEHAVIORAL: Transcutaneous electrical nerve stimulation|BEHAVIORAL: Transcutaneous electrical nerve stimulation and hypnosis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Enhancing Adolescent Substance Abuse Treatment
Status: ACTIVE_NOT_RECRUITING
Conditions: Substance Use Disorders
Interventions: BEHAVIORAL: Standard Contingency Management (CM)|BEHAVIORAL: Enhanced Contingency Management (CM+)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial of a New Type of Photodynamic Therapy (VTP) in the Treatment of Patients With Cancer of the Esophagus Who Have Trouble Swallowing
Status: ACTIVE_NOT_RECRUITING
Conditions: Esophagogastric Cancer|Moderate to Severe Dysphagia
Interventions: DRUG: WST 11-mediated VTP therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Liver Regeneration Therapy by Intrahepatic Arterial Administration of Autologous Adipose Tissue Derived Stromal Cells
Status: COMPLETED
Conditions: Liver Cirrhosis
Interventions: BIOLOGICAL: adipose tissue derived stromal cells dosage
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: U0289-401: Eight Week, Split-face, Study to Determine and Compare the Efficacy and Tolerability of MAXCLARITY™ II to PROACTIV™
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: OTHER: MAXCLARITY II (2.5% BPO) Foam Cleanser|OTHER: MAXCLARITY II (2.5% BPO) Foam Treatment|OTHER: MAXCLARITY II (0.5% Salicylic Acid) Toner Foam|OTHER: PROACTIV (2.5% BPO) Renewing Cleanser|OTHER: PROACTIV (2.5% BPO) Repairing Lotion|OTHER: PROACTIV (2.5% BPO) Revitalizing Toner
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bleeding Time Study With AZD6482, Clopidogrel and ASA
Status: COMPLETED
Conditions: Antiplatelet Effect
Interventions: DRUG: AZD6482|DRUG: Clopidogrel|DRUG: ASA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Research Study to Compare Two Types of Insulin, a New Weekly Insulin, Insulin Icodec and an Available Daily Insulin, Insulin Glargine, Both in Combination With Mealtime Insulin, in People With Type 2 Diabetes Who Use Daily Insulin and Mealtime Insulin (ONWARDS 4)
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Insulin icodec|DRUG: Insulin glargine|DRUG: Insulin aspart
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Screening for HPV and Cervical Cancer in Young Women With Perinatally Acquired HIV
Status: UNKNOWN
Conditions: HIV Infections|Human Papillomavirus Infection|Cervical Cancer
Interventions: DIAGNOSTIC_TEST: Human papillomavirus testing|DIAGNOSTIC_TEST: Cervical cytology|DIAGNOSTIC_TEST: HPV serology
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Antithymocyte Globulin Compared With Supportive Care in Treating Patients With Myelodysplastic Syndrome
Status: COMPLETED
Conditions: Myelodysplastic Syndromes
Interventions: BIOLOGICAL: anti-thymocyte globulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Self-Management and Activation to Reduce Treatment-Related Toxicities (SMARTCare)
Status: TERMINATED
Conditions: Lymphoma|Lung Cancer|Colo-rectal Cancer
Interventions: OTHER: SMARTCare|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Valemetostat Tosylate (DS-3201b) Phase 2 Study in Relapsed or Refractory Adult T-cell Leukemia/Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Adult T-cell Leukemia/Lymphoma
Interventions: DRUG: Valemetostat Tosylate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose, Safety, and Pathogenicity of a New Influenza H1N1 Challenge Strain
Status: COMPLETED
Conditions: Influenza A H1N1
Interventions: OTHER: Infectious Titre 1|OTHER: Infectious Titre 2|OTHER: Infectious Titre 3|OTHER: Infectious Titre 4
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Placenta, Fetal Liver, Sectional Ductus Venosus Volumes Examined by Three-dimensional Ultrasound in the Second Trimester
Status: COMPLETED
Conditions: Gestational Diabetes|DUCTUS VENOSUS VOLUME|PLACENTA VOLUME|3D SONOGRAPHY|FETAL LİVER VOLUME
Interventions: OTHER: 3D sonography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Efficacy and Safety of Efpeglenatide Versus Placebo in Patients With Type 2 Diabetes Mellitus Inadequately Controlled With Diet and Exercise
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: efpeglenatide (SAR439977)|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ultrasound Guided Botulinum Toxin Type A Injection of Subacromial-Subdeltoid Bursa in Hemiplegic Shoulder Pain
Status: UNKNOWN
Conditions: Subacromial Bursitis|Subdeltoid Bursitis
Interventions: DRUG: botulinum toxin type A|DRUG: Methyl Prednisolonate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Trial Comparing Early "Trigger" Versus Delayed "Trigger" Timing in Cycles of Controlled Ovarian Stimulation.
Status: RECRUITING
Conditions: Infertility, Female
Interventions: PROCEDURE: Ovulatory trigger timing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: S1316, Surgery or Non-Surgical Management in Treating Patients With Intra-Abdominal Cancer and Bowel Obstruction
Status: COMPLETED
Conditions: Constipation, Impaction, and Bowel Obstruction|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: PROCEDURE: therapeutic conventional surgery|PROCEDURE: gastrointestinal complications management/prevention|OTHER: quality-of-life assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study to Evaluate the Efficacy and Safety of Deferasirox Film-coated Tablet Versus Phlebotomy in Patients With Hereditary Hemochromatosis (HH)
Status: TERMINATED
Conditions: Hereditary Hemochromatosis
Interventions: DRUG: Deferasirox FCT|PROCEDURE: Phlebotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nitrous Oxide for Identifying the Intersegmental Plane in Segmentectomy: A Randomized Controlled Trial
Status: COMPLETED
Conditions: Pulmonary Nodule, Solitary|Pulmonary Nodule, Multiple|Lung Cancer
Interventions: PROCEDURE: nitrous oxide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Management Strategies for Patients With Low Back Pain and Sciatica
Status: COMPLETED
Conditions: Low Back Pain|Sciatica|Physical Therapy
Interventions: BEHAVIORAL: Education and re-assurance|PROCEDURE: Physical Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Determination of Salivary Soluble Urokinase Plasminogen Activator Receptor (SuPAR), Hypoxia-inducible Factor-1 Alpha (HIF-1α), E-cadherin, Galectin 3, IL-4, IL-10 and TNF-α Levels in Individuals With Different Degrees of Periodontal Disease
Status: NOT_YET_RECRUITING
Conditions: Periodontitis|Periodontal Diseases
Interventions: DIAGNOSTIC_TEST: Clinical measurements and saliva samples collection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Protocol for Primary Fractionated Stereotactic Body Radiation Therapy for Stage T1 - T3N0 Non Small Cell Lung Carcinoma.
Status: UNKNOWN
Conditions: Non Small Cell Lung Carcinoma
Interventions: RADIATION: Fractionated stereotactic body radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multicentric Study Comparison Between Erythropoietin and Erythropoietin Associated to Differentiating Therapy With Acid 13-cis-retinoic and Dihydroxyvitamin D3 in Myelodysplastic Syndromes Without Excess of Blasts
Status: TERMINATED
Conditions: Myelodysplastic Syndromes
Interventions: DRUG: infusion A: rEPO|DRUG: B Infusion rEPO combined with vitamins pills
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Eye MOvement DesensItisation and Reprocessing Therapy (EMDR) for FunctIonal Neurological Disorder (FND)
Status: ACTIVE_NOT_RECRUITING
Conditions: Functional Neurological Symptom Disorder
Interventions: OTHER: Eye movement desensitisation and reprocessing therapy|OTHER: Neuropsychiatric care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Safety and Efficacy of IV Nerofe™ Followed by Doxorubicin, In Metastatic Ovarian Cancer and Triple Negative Breast Cancer
Status: WITHDRAWN
Conditions: Metastatic Ovarian Cancer|Triple Negative Breast Cancer
Interventions: BIOLOGICAL: Nerofe is a first in class derivative of a human hormon-peptide(TCApF), with Cancer suppressive properties.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Remote Dynamic Cycling for the Customized Off-site Rehab in Parkinson's Disease
Status: RECRUITING
Conditions: Parkinson's Disease
Interventions: OTHER: Dynamic cycling|OTHER: Forced cycling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II Study of Age-Adjusted Rituximab, Bendamustine, Cytarabine as Induction Therapy in Older Patients With MCL
Status: COMPLETED
Conditions: Mantle Cell Lymphoma
Interventions: DRUG: Rituximab, Bendamustine, Cytarabine.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Combining Ibrutinib With Rituximab, Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone in Patients With CD20-Positive B-Cell Non Hodgkin Lymphoma
Status: COMPLETED
Conditions: CD20-positive B-cell Non-Hodgkin Lymphoma
Interventions: DRUG: Part 1, Cohort 1|DRUG: Part 1, Cohort 2|DRUG: Part 1, Cohort 3|DRUG: Part 2, Cohort 1|DRUG: Part 2, Cohort 2
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Celecoxib in Treating Patients With Stage I, Stage II, or Stage IIIA Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DRUG: celecoxib|PROCEDURE: biopsy|PROCEDURE: therapeutic conventional surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Calorie-restricted, Ketogenic Diet and Transient Fasting During Reirradiation for Patients With Recurrent Glioblastoma
Status: COMPLETED
Conditions: Recurrent Glioblastoma
Interventions: DIETARY_SUPPLEMENT: calorie-restricted ketogenic diet and transient fasting|DIETARY_SUPPLEMENT: standard nutrition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PEG-Interferon Alfa-2b and Sorafenib in Treating Patients With Unresectable or Metastatic Kidney Cancer
Status: TERMINATED
Conditions: Kidney Cancer
Interventions: BIOLOGICAL: PEG-interferon alfa-2b|DRUG: Sorafenib|GENETIC: gene expression analysis|GENETIC: polymerase chain reaction|GENETIC: reverse transcriptase-polymerase chain reaction|OTHER: flow cytometry|OTHER: immunoenzyme technique|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Avoiding Cardiovascular Events Through Combination Therapy in Patients Living With Systolic Hypertension
Status: TERMINATED
Conditions: Hypertension
Interventions: DRUG: Benazepril/amlodipine 20/5 mg - Dose Level 1 from Day 1 to Month 1|DRUG: Benazepril/amlodipine 40/5 mg - Dose Level 2 from Month 1 to Month 2|DRUG: Benazepril/amlodipine 40/10 mg - Dose Level 3 from Month 2 to Month 3 and thereafter|DRUG: Benazepril/hydrochlorothiazide 20/12.5 mg - Dose Level 1 from Day 1 to Month 1|DRUG: Benazepril/hydrochlorothiazide 40/12.5 mg - Dose Level 2 from Month 1 to Month 2|DRUG: Benazepril/hydrochlorothiazide 40/25 mg - Dose Level 3 from Month 2 to Month 3 and thereafter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of PM8002 (Anti-PD-L1/VEGF) in Combination With Chemotherapy in Patients With ES-SCLC
Status: RECRUITING
Conditions: SCLC
Interventions: DRUG: PM8002|DRUG: Platinum|DRUG: Atezolizumab|DRUG: Etoposide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Central Line-associated Bloodstream Infection Prevention Using TauroLock-Hep100 in Pediatric Oncology Patients.
Status: RECRUITING
Conditions: Central Line-associated Bloodstream Infection (CLABSI)
Interventions: DEVICE: TauroLock-Hep100 (taurolidine 1.35%, citrate 4%, heparin 100 IU/mL)|DEVICE: Heparin lock (heparin 100 IU/mL)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of 4 Doses of QGE031 in Patients 18-50 Years of Age With Peanut Allergy
Status: WITHDRAWN
Conditions: Peanut Allergy
Interventions: DRUG: QGE031|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Start or STop Anticoagulants Randomised Trial (SoSTART)
Status: COMPLETED
Conditions: Intracranial Hemorrhages|Intracranial Hemorrhage, Hypertensive|Subarachnoid Hemorrhage|Subdural Hematoma|Intraventricular Hemorrhage|Atrial Fibrillation|Atrial Flutter|Small Vessel Cerebrovascular Disease|Microhaemorrhage
Interventions: DRUG: Apixaban|DRUG: Rivaroxaban|DRUG: Edoxaban|DRUG: Dabigatran|DRUG: Acenocoumarol|DRUG: Phenindione|DRUG: Warfarin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Radiosurgery and Avastin for Recurrent Malignant Gliomas
Status: COMPLETED
Conditions: Malignant Glioma
Interventions: RADIATION: Stereotactic Radiosurgery (SRS)|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Safety of Levetiracetam Versus Fosphenytoin in Convulsive Status Epilepticus
Status: ENROLLING_BY_INVITATION
Conditions: Status Epilepticus
Interventions: DRUG: Levetiracetam Injection|DRUG: Fosphenytoin Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hepatic Insulin Sensitivity and Very Low Density Lipoprotein Triglyceride (VLDL-TG) Kinetics
Status: COMPLETED
Conditions: Obesity|Dyslipidemia
Interventions: OTHER: Glucose clamp
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Hetrombopag for Pediatric Patients With Chronic Immune Thrombocytopenia
Status: UNKNOWN
Conditions: Immune Thrombocytopenia
Interventions: DRUG: Hetrombopag|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Yoga for Mental Health in Parkinson's Patients
Status: RECRUITING
Conditions: Stress|Anxiety|Depression|Parkinson Disease
Interventions: BEHAVIORAL: Isha Kriya|BEHAVIORAL: Nadi Shuddhi|BEHAVIORAL: Nada Yoga|OTHER: Routine Daily Activity
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of a Serious Game for Individuals With SCI/D
Status: COMPLETED
Conditions: Spinal Cord Injury|Spinal Cord Involvement|Spina Bifida|Transverse Myelitis|Polio and Post-polio Syndrome|Syringomyelia|Spinal Stenosis|Spinal Neoplasms|Spinal Cord Diseases
Interventions: BEHAVIORAL: SCI Hard
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Skin Irritation Potential With PF-06700841 Cream Formulation Using Negative Control in Adult Japanese Healthy Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: PF-06700841 cream|DRUG: White petrolatum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intermittent Oro-esophageal Tube Feeding on Cerebral Small Vessel Disease Patients With Dysphagia
Status: TERMINATED
Conditions: Cerebral Small Vessel Diseases
Interventions: DEVICE: Nasogastric tube|DEVICE: Intermittent Oro-esophageal Tube
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Baduanjin Exercise Combined With Rational Emotive Behavior Therapy on Sleep and Mood in Patients With Post-stroke Depression
Status: COMPLETED
Conditions: Stroke
Interventions: BEHAVIORAL: Baduanjin|BEHAVIORAL: Rational emotive behavior therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Development and Validation of a Screening Score for the Biliary Atresia in Infantile Cholestasis: A Prospective Study
Status: RECRUITING
Conditions: Biliary Atresia|Neonatal Cholestasis|Infantile Hepatitis Syndrome
Interventions: DIAGNOSTIC_TEST: biliary atresia screen score
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of a Western-type Diet on Colorectal Inflammation
Status: COMPLETED
Conditions: Colorectal Inflammation
Interventions: DIETARY_SUPPLEMENT: Western style diet (high fat and low in calcium)|DIETARY_SUPPLEMENT: Prudent-style diet (low fat and high in calcium)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Double-blind Study to Evaluate the PK, Efficacy, Safety and Immunogenicity of MB12 Versus Keytruda® in Stage IV NSCLC
Status: RECRUITING
Conditions: Non Small Cell Lung Cancer Metastatic
Interventions: DRUG: Pembrolizumab|DRUG: Pembrolizumab biosimilar
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, Pharmacokinetics and Anti-tumour Activity of ASK120067 in Locally Advanced and Metastatic Non Small Cell Lung Cancer
Status: UNKNOWN
Conditions: Locally Advanced or Metastatic NSCLC
Interventions: DRUG: ASK120067
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of scFOS on Stool Frequency in People With Functionnal Constipation
Status: COMPLETED
Conditions: Functional Constipation
Interventions: DIETARY_SUPPLEMENT: Short-chain fructo-oligosaccharides|DIETARY_SUPPLEMENT: Maltodextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Evaluation of a New Design of Crowns in the Posterior Teeth
Status: COMPLETED
Conditions: Broken Down Molars|IPS-emmax Crowns
Interventions: OTHER: IPS.emmax endocrown
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neuromodulation for Children With Cystic Fibrosis Experiencing Chronic Abdominal Pain
Status: TERMINATED
Conditions: Cystic Fibrosis|Irritable Bowel Syndrome|Chronic Pain
Interventions: DEVICE: Use of neurostimulation device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Quality of Postoperative Pain Management Following Thoracic Surgery
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: OTHER: Assessment of pain using the Brief Pain Questionnaire|OTHER: Assessment of pain relief using a Verbal Numeric Scale (VNS)|OTHER: Assessment of patient' satisfaction with pain relief|OTHER: Nurse's satisfaction with patient's pain relief and recovery
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety of Intravenous YOLT-201 for Transthyretin Amyloidosis Cardiomyopathy
Status: RECRUITING
Conditions: Transthyroxin Amyloidosis Cardiomyopathy
Interventions: DRUG: YOLT-201
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prophylactic Antibiotics Useful With Antibiotic Impregnated External Ventricular Drains (EVDs)?
Status: RECRUITING
Conditions: Subarachnoid Hemorrhage|Intracerebral Hemorrhage|Ventriculitis, Cerebral|Hydrocephalus
Interventions: DRUG: long term prophylactic antibiotics (Nafcillin or Doxycycline)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effects of Genistein in Postmenopausal Women With Metabolic Syndrome
Status: COMPLETED
Conditions: Metabolic Syndrome
Interventions: DIETARY_SUPPLEMENT: Genistein|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Daily Remote Ischemic Conditioning on the Life Quality of Refractory Angina Pectoris Patients
Status: UNKNOWN
Conditions: Refractory Angina Pectoris
Interventions: DEVICE: remote ischemic conditioning (TDFT-12-A2)|DRUG: Optimal medical treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Assessing a Polydextrose Containing Soup on Food Intake, Appetite and Biomarkers of Satiation and Satiety
Status: TERMINATED
Conditions: Satiation, Satiety
Interventions: DIETARY_SUPPLEMENT: Polydextrose|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of Paclitaxel Plus Cisplatin as the First-line Chemotherapy in High Risk Gestational Trophoblastic Tumor
Status: RECRUITING
Conditions: Gestational Trophoblastic Neoplasms
Interventions: DRUG: Etoposide|DRUG: actinomycin D|DRUG: methotrexate|DRUG: vincristine|DRUG: cyclophosphamide|DRUG: Paclitaxel|DRUG: Cisplatin|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Maternal Probiotic Intervention to Improve Gut Health
Status: RECRUITING
Conditions: Environmental Enteric Dysfunction|Gut Microbiota Dysbiosis
Interventions: DIETARY_SUPPLEMENT: Vivomixx|DIETARY_SUPPLEMENT: Microcrystalline maltose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Study of Relationship of Plasma Concentrations of Folic Acid, Vitamin B and Homocysteine With Carotid Atherosclerosis and Endothelium-Dependent Vasodilatation of Geriatric and Young Patients in the Ambulatory Care Department of NTUH
Status: COMPLETED
Conditions: Homocysteine|Coronary Artery Disease
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Use of Ultrasonic Coagulating Shears Compared to Monopolar Electrocautery in Open Gastric Cancer Surgery
Status: UNKNOWN
Conditions: Stomach Cancer|Gastrectomy|Ultrasonic Coagulating Shears
Interventions: DEVICE: Ultrasonic Coagulating Shears
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Safety Study of Carfilzomib, Cyclophosphamide & Dexamethasone Prior to ASCT in Patients With Newly Diagnosed Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Carfilzomib|DRUG: Cyclophosphamide|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Bipolar Depression With H1-Coil Deep Brain rTMS: Clinical-Cognitive and Safety Evaluation
Status: COMPLETED
Conditions: Bipolar Depression
Interventions: DEVICE: Deep Brain Transcranial Magnetic Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Establishing Cardiovascular Biomarkers to Define Preferred Lantus® Use
Status: UNKNOWN
Conditions: Insulin-requiring Type 2 Diabetes Mellitus
Interventions: DRUG: nph insulin|DRUG: human insulin|DRUG: Insulin Glargine|DRUG: Insulin glulisine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hydroxyethyl Starch and Renal Function After Laparoscopic Nephrectomy
Status: TERMINATED
Conditions: Kidney Cancer
Interventions: DRUG: Voluven (Hydroxyethyl starch 130/0,4)|DRUG: Sodium Chloride 9mg/ml
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Antithrombotic Treatment in Patients With Effectively Maintained Sinus Rhythm After Atrial Fibrillation Ablation
Status: TERMINATED
Conditions: Atrial Fibrillation
Interventions: DRUG: Antiplatelet|DRUG: Low dose oral anticoagulant|DRUG: Standard dose oral anticoagulant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Safety and Effectiveness of ALKS 2680 in Subjects With Narcolepsy Type 1 (ALKS 2680-201)
Status: RECRUITING
Conditions: Narcolepsy Type 1
Interventions: DRUG: ALKS 2680|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Insulin Degludec and Symptomatic Nocturnal Hypoglycaemia
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus|Nocturnal Hypoglycemia|Recurrent Severe Hypoglycaemia
Interventions: DRUG: Insulin aspart/glargine|DRUG: Insulin aspart/degludec
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Aspalathus Linearis on Muscle Soreness and Post-exercise Recovery in Young, Physically Inactive Women
Status: COMPLETED
Conditions: Inflammation|Muscle Recovery|Muscle Soreness
Interventions: OTHER: Rooibos tea|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT