pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Paracervical Block During Office Hysteroscopy
Status: COMPLETED
Conditions: Paracervical Block
Interventions: DRUG: Lidocaine paracervical block|DRUG: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Semaglutide and Cognition in Healthy Volunteers
Status: RECRUITING
Conditions: Cognitive Change
Interventions: DRUG: Semaglutide, 0.5 mg/mL|OTHER: Placebo, 0.9% NaCl 1.5mL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Nalox-Comm: Naloxone Communication Training for Pharmacists
Status: COMPLETED
Conditions: Naloxone
Interventions: BEHAVIORAL: Nalox-comm Training Module|BEHAVIORAL: Prescribe to Prevent: Overdose Prevention and Naloxone Rescue Kits for Prescribers and Pharmacists
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Cranial Cup Use for the Prevention of Positional Head Shape Deformity in the NICU
Status: TERMINATED
Conditions: Plagiocephaly|Scaphocephaly|Brachycephaly
Interventions: DEVICE: Cranial cup device and Moldable positioner|DEVICE: Moldable positioner device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison Between Bupivacaine With and Without Fentanyl in Reducing Pain During Cesarean Delivery Under Spinal Anaesthesia
Status: COMPLETED
Conditions: Visceral Pain
Interventions: DRUG: 0.5% bupivacaine heavy|DRUG: 0.5% bupivacaine heavy with fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Investigation of the Association Between Nasal Polyposis and Extraesophageal Reflux Disease
Status: COMPLETED
Conditions: Nasal Polyps|Gastroesophageal Reflux
Interventions: DRUG: lansoprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Subacute Low Back Pain in Active Duty
Status: COMPLETED
Conditions: Subacute Low Back Pain
Interventions: BEHAVIORAL: Progressive Exercise Plan|DEVICE: NeuromuscularElectricalStimulation(NMES)|BEHAVIORAL: Primary Care Management (PCM)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combinations of Pharmacologic Smoking Cessation Treatments
Status: COMPLETED
Conditions: Smoking
Interventions: DRUG: Bupropion|DRUG: Mecamylamine|DRUG: Nicotine Patch
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of 0.75% Ropivacaine Topicalization on Emergence Agitation in Children
Status: UNKNOWN
Conditions: Tonsillitis
Interventions: DRUG: normal saline|DRUG: ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Bioequivalence Study of Trandolapril 4 mg Tablets of Dr. Reddy's Under Fasting Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Trandolapril|DRUG: Mavik
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of ECP Therapy in Stable Angina Pectoris Patients
Status: RECRUITING
Conditions: Counterpulsation|Angina Pectoris
Interventions: DEVICE: External Counter Pulsation (ECP) therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Fludarabine/Carboplatin/Topotecan w/Thalidomide for Relapsed/Refractory AML, CML and MDS
Status: COMPLETED
Conditions: Leukemia|Myelodysplastic Syndromes|Myelodysplastic/Myeloproliferative Diseases
Interventions: DRUG: carboplatin|DRUG: fludarabine phosphate|DRUG: thalidomide|DRUG: topotecan hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vosaroxin and Infusional Cytarabine in Treating Patients With Untreated Acute Myeloid Leukemia
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Myeloid Leukemia|Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome|Acute Myeloid Leukemia With Multilineage Dysplasia|Myeloid Sarcoma|Secondary Acute Myeloid Leukemia|Therapy-Related Acute Myeloid Leukemia|Therapy-Related Myelodysplastic Syndrome
Interventions: DRUG: Cytarabine|DRUG: Vosaroxin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sitagliptin for the Treatment of Grade 3-4 and Refractory Acute Graft-versus-host Disease
Status: UNKNOWN
Conditions: Graft Vs Host Disease
Interventions: DRUG: Sitagliptin 100mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Trial to Examine a Differential Therapeutic Response in Symptomatic Patients With Non-obstructive Coronary Artery Disease
Status: UNKNOWN
Conditions: Coronary Microvascular Dysfunction|Microvascular Angina|Vasospasm, Coronary|Vasospastic Angina|Prinzmetal Angina|Coronary Artery Disease
Interventions: DRUG: Bisoprolol|DRUG: Diltiazem|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Blood TMB for the Efficacy of Atezolizumab [BUDDY]
Status: COMPLETED
Conditions: Lung Neoplasm Malignant
Interventions: DRUG: Atezolizumab Injection [Tecentriq]
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Alternative Healthcare Delivery Strategies to Prevent Weight Regain After Bariatric Surgery
Status: ACTIVE_NOT_RECRUITING
Conditions: Obesity Adult Onset|Eating Behavior
Interventions: BEHAVIORAL: Apolo_Bari Stepped-care intervention|OTHER: Treatment as Usual for Bariatric Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Immunogenicity of Two Adjuvanted and One Non-adjuvanted H5N1 Influenza Vaccine in Adults
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: MF59 adjuvanted H5N1 influenza vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Blended Treatment för PTSD: A New Format of Computer-Assisted Trauma-Focused Cognitive Behavioral Therapy
Status: RECRUITING
Conditions: PTSD|CBT
Interventions: BEHAVIORAL: Blended Trauma focused Cognitive Behavioral Therapy (B-Tf-CBT)|BEHAVIORAL: Prolonged exposure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility Study of HIPEC for Patients With Stage III or Only Pleural Stage IV Ovarian Carcinoma in First Line Therapy
Status: COMPLETED
Conditions: Ovarian Carcinoma|Fallopian Tube Carcinoma|Primary Peritoneal Carcinoma
Interventions: PROCEDURE: HIPEC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Research Study Looking at the Safety of Multiple Doses of ZP8396 and How it Works in the Body of Healthy Participants
Status: COMPLETED
Conditions: Overweight|Healthy Volunteers|Obese
Interventions: DRUG: ZP8396|DRUG: Drug: Placebo (ZP8396)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Saccharomyces Cerevisiae CNCM I-3856 Treatment in Irritable Bowel Syndrome With Diarrhea (IBS-D) and Post Infective Bowel Dysfunction
Status: WITHDRAWN
Conditions: Irritable Bowel Syndrome|Post Infective Bowel Dysfunction
Interventions: DRUG: Saccharomyces Cerevisiae CNCM I-3856|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Aerobic Combined With Diaphragmatic Breathing Exercise in Smokers
Status: COMPLETED
Conditions: Smoker Lung|Smoking Cessation
Interventions: OTHER: aerobic combined with diaphragmatic breathing exercise (EXDB)|OTHER: aerobic exercise (EX)|OTHER: sedentary control (CON)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized Controlled Trial of Lung Ultrasound Compared to Chest X-ray for Diagnosing Pneumonia in the Emergency Department
Status: COMPLETED
Conditions: Pneumonia
Interventions: OTHER: Lung Ultrasound|RADIATION: Chest X-Ray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Prophylactic Treatment of Episodic Cluster Headache
Status: COMPLETED
Conditions: Cluster Headache
Interventions: DRUG: candesartan cilexetil|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pedi-Cap CO2 Detector for Face-mask Ventilation in the Delivery Room
Status: RECRUITING
Conditions: Neonatal Resuscitation|Neonatal Disease
Interventions: DEVICE: Pedi-Cap
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation of Second Esmarch Application on Intravenous Regional Anesthesia Effectiveness
Status: UNKNOWN
Conditions: Hand Injuries and Disorders|Anesthesia, Local|Upper Extremity Injury
Interventions: PROCEDURE: standard intravenous regional anesthesia (IVRA) with reapplication of esmach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Robotic Cholecystectomy Using the Chinese Micro Hand S Robot: A Controlled, Randomized, Prospective Clinical Study
Status: COMPLETED
Conditions: Cholecystitis; Gallstone
Interventions: OTHER: robot-assisted cholecystectomy|OTHER: robot-assisted cholecystectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Acute Clinical Evaluation of Multi-purpose Solutions (MPS) in Soft Contact Lens Wearers
Status: COMPLETED
Conditions: Myopia
Interventions: DEVICE: Contact lens multi-purpose solution|OTHER: Saline/blister pack solution|DEVICE: Contact lenses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: African Americans (AA) Communities Speak
Status: NOT_YET_RECRUITING
Conditions: Healthy Aging|Health Knowledge, Attitudes, Practice|Social Responsibility|Care Eliciting Behavior|Racism, Systemic
Interventions: BEHAVIORAL: AA Communities Speak to Healthcare Professionals
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Autologous Serum Efficacy Study in Patients With Severe Dry Eye
Status: COMPLETED
Conditions: Dry Eye
Interventions: DRUG: Autologous serum - Systane|DRUG: Systane - Autologous serum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Renal Effects of Meditarranean Diet and Low-protein Diet With Ketoacids on Physiological Intestinal Mibrobiota in CKD
Status: UNKNOWN
Conditions: Chronic Renal Insufficiency
Interventions: DIETARY_SUPPLEMENT: Ketoacids diet|OTHER: Mediterranean diet|OTHER: Free diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Defining a Vascular Phenotype of Pancreatic Ductal Adenocarcinoma With CT Perfusion Using Quantitative Radiomics
Status: RECRUITING
Conditions: PDAC - Pancreatic Ductal Adenocarcinoma
Interventions: DIAGNOSTIC_TEST: CT Perfusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy and Safety of Fluticasone Furoate/Umeclidinium/Vilanterol (FF/UMEC/VI) in Chinese Participants With Inadequately Controlled Asthma
Status: RECRUITING
Conditions: Asthma
Interventions: DRUG: FF/VI|DRUG: FF/UMEC/VI|DEVICE: ELLIPTA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study To Investigate The Effects Of GW856553 On Patients With COPD (Chronic Obstructive Pulmonary Disease)
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive|Chronic Obstructive Pulmonary Disease (COPD)
Interventions: DRUG: GW856553
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Molecular Breast Imaging in Women With Atypia and LCIS
Status: COMPLETED
Conditions: Atypical Lobular Hyperplasia|Atypical Ductal Hyperplasia|Lobular Carcinoma in Situ
Interventions: PROCEDURE: Molecular Breast Imaging|PROCEDURE: Screening Mammography
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: SABR-ATAC: A Trial of TGF-beta Inhibition and Stereotactic Ablative Radiotherapy for Early Stage Non-small Cell Lung Cancer
Status: COMPLETED
Conditions: Stage IA Non-Small Cell Lung Carcinoma|Stage IB Non-Small Cell Lung Carcinoma
Interventions: BIOLOGICAL: Fresolimumab|RADIATION: Stereotactic Body Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non-invasive Ventilation vs Oxygen Therapy After Extubation Failure
Status: COMPLETED
Conditions: Respiratory Failure
Interventions: DEVICE: Non-invasive mechanical ventilation|DEVICE: Continuous positive airway pressure|DEVICE: Venturi mask|DEVICE: Reservoir mask
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety of PENTAXIM® Given as a Three-Dose Primary Vaccination at 2, 3, and 4 Months of Age in Infants in China
Status: COMPLETED
Conditions: Diphtheria|Tetanus|Pertussis|Polio
Interventions: BIOLOGICAL: DTacP IPV//PRP~T combined vaccine: PENTAXIM®
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of ASA404 or Placebo in Combination With Docetaxel in Second-line Treatment for (Stage IIIb/IV) Non-small Cell Lung Cancer
Status: TERMINATED
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: ASA404|DRUG: Placebo|DRUG: docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Perspective, Self-control Study on the Progression of Carotid Plaques in Anti-PD-1 mAb Treated Tumor Patients by Artery Ultrasound Follow-up
Status: UNKNOWN
Conditions: Plaque, Atherosclerotic|Immune Checkpoint Inhibitors|Programmed Cell Death Protein 1 Inhibitor|Carotid Artery Plaque|Intimal Medial Thickness of Internal Carotid Artery
Interventions: DRUG: PD-1 immune checkpoint blockades
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Omega Loop Gastric Bypass With And Without Anti-Reflux Sutures
Status: UNKNOWN
Conditions: Bile Reflux
Interventions: PROCEDURE: Omega Loop Gastric Bypass|DEVICE: Bilitec 2000™|DEVICE: V-Loc
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: DIAGNOSTIC
Clinical trial: Package of Interventions After Recovering From Moderate Acute Malnutrition
Status: COMPLETED
Conditions: Malnutrition
Interventions: DIETARY_SUPPLEMENT: Lipid Nutrient Supplement|DRUG: Sulfadoxine-pyrimethamine|DRUG: Albendazole|DRUG: Zinc|OTHER: Insecticide-treated bednet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Single and Multiple-Ascending Dose Study of CRN04894 in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: CRN04894 Oral Solution|DRUG: Placebo Oral Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective Randomized Double Blind Clinical Trial of Polyhexamethylene Biguanide Impregnated Foam Dressing
Status: COMPLETED
Conditions: Wounds
Interventions: DEVICE: COPA AMD (note: name is not an acronym)|DEVICE: COPA (note: name is not an acronym)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cooling Anesthesia for Intravitreal Injection
Status: COMPLETED
Conditions: Anesthesia, Local|Intravitreal Injection|Macular Degeneration|Diabetic Macular Edema
Interventions: DEVICE: Cooling Anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Of The Efficacy Of Gabapentin In Neuropathic Pain Patients As Measured By Quantitative Sensory Testing
Status: COMPLETED
Conditions: Neuralgia|Neuralgia, Postherpetic
Interventions: DRUG: 2-weeks placebo then gabapentin|DRUG: 1-week placebo then gabapentin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Social Support Intervention to Improve Treatment Among Hispanic Kidney and Liver Cancer Patients in Arizona
Status: WITHDRAWN
Conditions: Renal Cell Carcinoma|Hepatocellular Carcinoma
Interventions: BEHAVIORAL: Social Support Network Intervention|BEHAVIORAL: Control (Patient Navigation Service)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Evaluate the Safety, Tolerability, and Pharmacokinetics of ICP-723 in Patients With Advanced Solid Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Solid Tumors
Interventions: DRUG: ICP-723
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Lonsurf in Combination With Gemcitabine and Nab-Paclitaxel in Patients With Advanced (PDAC)
Status: TERMINATED
Conditions: Pancreatic Cancer|Pancreatic Ductal Adenocarcinoma
Interventions: DRUG: Lonsurf|DRUG: Gemcitabine|DRUG: Nab-Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RCT Novasure Versus Novasure + Mirena IUS in the Treatment of Menorrhagia
Status: UNKNOWN
Conditions: Menorrhagia
Interventions: PROCEDURE: novasure mirena IUS combined
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Six Months Efficacy and Safety of Aliskiren Therapy on Top of Standard Therapy, on Morbidity and Mortality in Patients With Acute Decompensated Heart Failure
Status: COMPLETED
Conditions: Acute Decompensated Heart Failure|Congestive Heart Failure
Interventions: DRUG: Aliskiren|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of an Adult EDUcation Program on CArdiovascular ouTcomEs in Post-myocardial-infarction Patients
Status: UNKNOWN
Conditions: Myocardial Infarction
Interventions: OTHER: Adult education program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: An Evaluation Trial About Anti-claudin18.2 the Specificity of Chimeric Antigen Receptor T Cells in the Advanced Gastric / Esophagogastric Junction Adenocarcinoma and Pancreatic Cancer Subjects
Status: RECRUITING
Conditions: CAR T-Cell Therapy
Interventions: DRUG: HEC-016(0.5×10^6 CAR-T Cells)|DRUG: HEC-016(0.5×10^6.5 CAR-T Cells)|DRUG: HEC-016(0.5×10^7 CAR-T Cells)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Acute Effects of Interesterification of Commercially Used Fats on Postprandial Lipaemia and Satiety
Status: COMPLETED
Conditions: Healthy Men
Interventions: DIETARY_SUPPLEMENT: Interesterified blend of palm kernal and plam stearin|DIETARY_SUPPLEMENT: Un-interesterified blend of palm kernal and plam stearin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Genetic Susceptibility to Tumor Recurrence and Progression in Patients With Non-Muscle Invasive Bladder Cancer
Status: COMPLETED
Conditions: Bladder Cancer|Urinary Cancer|Nonmuscle Invasive Bladder Cancer
Interventions: GENETIC: specimen samples|BEHAVIORAL: questionnaires
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Maraviroc (Celsentri) With Raltegravir and Darunavir/Ritonavir for the Treatment of Triple Class Failure in Adult HIV-1 Infected Patients
Status: UNKNOWN
Conditions: HIV-1 Adults Patients|AIDS|Triple Class Failure
Interventions: DRUG: maraviroc|DRUG: Raltegravir|DRUG: Darunavir/ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Binge Eating Self-help for Teens ONLINE Pilot and Feasibility Study
Status: RECRUITING
Conditions: Binge Eating|Binge-Eating Disorder|Overweight or Obesity
Interventions: BEHAVIORAL: Binge Eating Self-help for Teens
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Effect of Improving Systolic BP and LDL-C Compared to Conventional Treatments and the Convenience of Taking Medication of Olostar Tab
Status: ACTIVE_NOT_RECRUITING
Conditions: Hyperlipidemias|Hypertension
Interventions: DRUG: Rosuvastatin, Olmesartan Medoxomil
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Incidence of Paroxysmal Atrial Fibrillation (AF) in Patients With Acute Ischemic Stroke or Transient Ischemic Attacks (TIAs) by 48 Hours Holter Monitoring
Status: COMPLETED
Conditions: Transient Ischemic Attack
Interventions: DIAGNOSTIC_TEST: Holter ECG
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Cyriax Inferior Capsule Stretching in Idiopathic Adhesive Capsulitis
Status: COMPLETED
Conditions: Adhesive Capsulitis
Interventions: OTHER: Cyriax inferior capsular stretching + Manual Therapy|OTHER: Manual therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effects of LRYGB on Pharmacokinetics of Nine CYP Probe Drugs
Status: COMPLETED
Conditions: Obesity, Morbid|Bariatric Surgery Candidate
Interventions: DRUG: cocktail of nine CYP probe drugs
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study on the Immune Response and Safety of Vaccine Against Respiratory Syncytial Virus (RSV) Given to Adults 18 to 49 Years of Age at Increased Risk for Respiratory Syncytial Virus Disease, Compared to Older Adults 60 Years of Age and Above
Status: RECRUITING
Conditions: Respiratory Syncytial Virus Infections
Interventions: BIOLOGICAL: RSVPreF3 OA investigational vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of EYP001a in Healthy Volunteers and Nonalcoholic Steatohepatitis Patients
Status: COMPLETED
Conditions: NASH - Nonalcoholic Steatohepatitis|Healthy
Interventions: DRUG: EYP001a
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cetuximab in Combination With Dabrafenib and Tislelizumab in BRAF Mutated Treatment of Advanced Colorectal Cancer
Status: NOT_YET_RECRUITING
Conditions: Advanced Colorectal Cancer
Interventions: DRUG: Cetuximab Dabrafenib Tislelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fish Oil Supplementation and Vascular Function in Hypertensive Patients With Hypertriglyceridemia
Status: UNKNOWN
Conditions: Hypertension|Hypertriglyceridemia
Interventions: DIETARY_SUPPLEMENT: DHA-EPA|DRUG: Ciprofibrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Multiple Escalating Oral Doses Study of PF-07081532 in Adult Participants With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus Type 2
Interventions: DRUG: PF-07081532|OTHER: Placebo|DRUG: Clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of Absorption, Metabolism, Excretion, and Absolute Bioavailability of Carbon-14-Labelled [14C] Selpercatinib (LY3527723) in Healthy Male Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: [14C] Selpercatinib|DRUG: Selpercatinib|DRUG: [14C] Selpercatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Telecoached Exercise Intervention for Connectivity Enhancement in Small Vessel Disease (TELECONNECT-SVD)
Status: NOT_YET_RECRUITING
Conditions: Lacunar Stroke|Small Vessel Cerebrovascular Disease
Interventions: BEHAVIORAL: Physical activity
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Placebo-Controlled Study of the Safety of INCB054707 in Participants With Hidradenitis Suppurativa
Status: COMPLETED
Conditions: Hidradenitis Suppurativa
Interventions: DRUG: INCB054707|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessing the Efficacy of Maxidex® and Patanol® for the Treatment of Allergic Conjunctivitis
Status: COMPLETED
Conditions: Allergic Conjunctivitis
Interventions: DRUG: Dexamethasone 0.1% ophthalmic suspension|DRUG: Olopatadine hydrochloride 0.1% ophthalmic solution|OTHER: Inactive ingredients, used as placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: GSK961081 Alone and With Fluticasone Furoate (FF), Phase 1 (Ph1), Single Dose Regimen (SD), Repeat Dose Regimen (RD), Pharmacokinetic (PK) Study in Healthy Volunteer (HV)
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: BAT/FF|DRUG: BAT|DRUG: FF|DRUG: FF (MgSt)|DRUG: FF/Vilanterol
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Single Centre Randomized Study Evaluating The Safety And Tolerability Of GSK233705 In Healthy Volunteers.
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: GSK233705
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Functional Electrical Stimulation Cycling for Managing Mobility Disability in People With Multiple Sclerosis
Status: RECRUITING
Conditions: Multiple Sclerosis
Interventions: OTHER: FES Cycling Exercise|OTHER: Passive Leg Cycling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Flavored Intravenous Ondansetron Administered Orally for the Treatment of Persistent Vomiting
Status: COMPLETED
Conditions: Gastroenteritis
Interventions: DRUG: Ondansetron with1:1 ORA - sweet.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of Plant-Derived Pfs25 VLP-FhCMB Malaria Transmission Blocking Vaccine in Healthy Adults
Status: COMPLETED
Conditions: Malaria
Interventions: BIOLOGICAL: Pfs25 VLP- FhCMB
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Azithromycin for Child Survival in Niger: Mortality and Resistance Trial
Status: RECRUITING
Conditions: Mortality|Resistance Bacterial|Child, Only
Interventions: DRUG: Azithromycin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of RS1 Ocular Gene Transfer for X-linked Retinoschisis
Status: ACTIVE_NOT_RECRUITING
Conditions: Retinoschisis|X-Linked
Interventions: BIOLOGICAL: RS1 AAV Vector
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Role of C-HAM in the Surgical Repair of Peroneal Tendons: An Infrared Thermography Model
Status: TERMINATED
Conditions: Tendon Tears
Interventions: BIOLOGICAL: Clarix™1k graft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Natural Carbonated Mineral Water Consumption on Gastrointestinal Transit and on Gut Microbiota in Subjects With Functional Constipation: A Randomized, Placebo-Controlled Pilot Trial
Status: UNKNOWN
Conditions: Functional Constipation
Interventions: OTHER: Carbonated Natural Mineral Water|OTHER: Low Mineral Water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Repetitive Transcranial Magnetic Stimulation and Intermittent Theta Burst (iTBS) in Schizophrenia
Status: UNKNOWN
Conditions: Schizophrenia
Interventions: DEVICE: repetitive Transcranial Magnetic Stimulation (Magstim rapid2 )|DEVICE: repetitive Transcranial Magnetic Stimulation (Magstim rapid2)|DEVICE: repetitive Transcranial Magnetic Stimulation(Magstim rapid2)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Paclitaxel (Taxol, NSC #673089), Carboplatin (Paraplatin, NSC #241240), and BSI-201 (NSC #746045, IND #71,677) in the Treatment of Advanced, Persistent, or Recurrent Uterine Carcinosarcoma
Status: COMPLETED
Conditions: Uterine Carcinosarcoma
Interventions: DRUG: paclitaxel|DRUG: carboplatin|DRUG: BSI-201 (Iniparib)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral Zinc for the Treatment of Acute Diarrhea in US Children
Status: COMPLETED
Conditions: Diarrhea|Gastroenteritis
Interventions: DRUG: Zinc Sulfate|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Mirror Therapy on Unilateral Neglect for Patients After Stroke
Status: COMPLETED
Conditions: The Effects of Mirror Therapy on Patients With Unilateral Neglect After Stroke
Interventions: BEHAVIORAL: Mirror therapy|BEHAVIORAL: Sham mirror|BEHAVIORAL: Covered mirror
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Levotofisopam 50 mg Three Times a Day (TID) Administered for 7 Days on Hyperuricemia and Gout
Status: UNKNOWN
Conditions: Hyperuricemia|Gout
Interventions: DRUG: levotofisopam
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Epidural Analgesia: Continuous Infusion Versus Programmed Intermittent Boluses
Status: COMPLETED
Conditions: Labor Pain
Interventions: DRUG: Bupivacaine and Fentanyl Initial Dose|DRUG: Bupivacaine and Fentanyl: Continuous Epidural Infusion|DRUG: Bupivacaine and Fentanyl: Programmed Intermittent Epidural Bolus|DRUG: Rescue Bolus|DRUG: Lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Tramadol Versus Celecoxib in Reducing Pain Associated With IUD Insertion
Status: UNKNOWN
Conditions: Pain
Interventions: DRUG: Tramadol|DRUG: Celecoxib|DRUG: Placebo 1|DRUG: Placebo 2|PROCEDURE: IUD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: An Investigational Immuno-therapy Study of Temozolomide Plus Radiation Therapy With Nivolumab or Placebo, for Newly Diagnosed Patients With Glioblastoma (GBM, a Malignant Brain Cancer)
Status: COMPLETED
Conditions: Brain Neoplasms
Interventions: DRUG: Nivolumab|DRUG: Temozolomide|RADIATION: Radiotherapy|OTHER: Nivolumab Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Investigation of the TECNIS 1-Piece Intraocular Lens
Status: WITHDRAWN
Conditions: Cataract
Interventions: DEVICE: Investigational mDCB00|DEVICE: Control DCB00
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Study of ENMD-2076 in Patients With Relapsed or Refractory Hematological Malignancies
Status: COMPLETED
Conditions: Relapsed or Refractory Hematological Malignancies
Interventions: DRUG: ENMD-2076
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Disturbed Sleep in Progressive Supranuclear Palsy (PSP)
Status: RECRUITING
Conditions: Treatment
Interventions: DRUG: Suvorexant|DRUG: Zolpidem|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hepatectomy With or Without Transcatheter Arterial Chemoembolization for Stage IIIA Hepatocellular Carcinoma
Status: COMPLETED
Conditions: Hepatocellular Carcinoma|Hepatectomy|Chemoembolization
Interventions: PROCEDURE: hepatectomy and transcatheter arterial chemoembolization|PROCEDURE: hepatectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Pill of Losartan Potassium and Hydrochlorothiazide for Improvement of Medication Compliance Trial
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Combination pill of losartan and hydrochlorothiazide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nitroglycerin Versus Terbutaline for Intrapartum Fetal Resuscitation
Status: COMPLETED
Conditions: Fetal Distress
Interventions: DRUG: Terbutaline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating Subcutaneous MOA-728 for the Treatment of Opioid-Induced Constipation (OIC) in Subjects With Chronic Non-Malignant Pain
Status: COMPLETED
Conditions: Constipation
Interventions: DRUG: N-methylnaltrexone bromide (MOA-728)|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficiency of an Algorithm Derived From Corneal Tomography Parameters to Distinguish Highly Susceptible Corneas to Ectasia From Healthy
Status: COMPLETED
Conditions: Keratoconus, Artificial Intelligence, Support Vector Machine
Interventions: DIAGNOSTIC_TEST: Corneal tomography multivariate index derived from a support vector machine (CTMVI).
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Fimepinostat in Treating Brain Tumors in Children and Young Adults
Status: ACTIVE_NOT_RECRUITING
Conditions: Diffuse Intrinsic Pontine Glioma|Recurrent Anaplastic Astrocytoma|Recurrent Glioblastoma|Recurrent Malignant Glioma|Recurrent Medulloblastoma
Interventions: DRUG: Fimepinostat|PROCEDURE: Therapeutic Conventional Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intraocular Pressure Data Collection With Tonometers
Status: RECRUITING
Conditions: Intraocular Pressure
Interventions: DEVICE: iCare IC1000|DEVICE: iCare ST500|DEVICE: iCare IC200|DEVICE: GAT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Double-Blind, Randomized, Placebo-Controlled Safety Study Evaluating the Effects of Residual Renal Function (RFF) in Patients With End-Stage Renal Disease and Type 2 Diabetes Mellitus on Peritoneal Dialysis
Status: WITHDRAWN
Conditions: End-Stage Renal Disease|Type 2 Diabetes Mellitus
Interventions: DRUG: Bardoxolone Methyl 20 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Performances of a Brief Assessment Tool for the Early Diagnosis of Geriatric Syndromes by Primary Care Physicians
Status: COMPLETED
Conditions: Cognitive Impairment|Mood Disorders|Urinary Incontinence|Malnutrition|Osteoporosis|Hearing Impairment|Visual Impairment
Interventions: OTHER: brief geriatric assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Cytoflavin in the Complex Rehabilitation of Stroke Patients
Status: RECRUITING
Conditions: Stroke
Interventions: DRUG: Cytoflavin (Inosine + Nicotinamide + Riboflavin + Succinic Acid)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Stereotactic Body Radiation Therapy (SBRT) Versus Trans-Arterial Chemoembolization (TACE) as Bridge to Liver Transplant
Status: COMPLETED
Conditions: Hepatocellular Carcinoma|HCC
Interventions: RADIATION: Stereotactic Body Radiation Therapy (SBRT)|PROCEDURE: Trans-Arterial Chemoembolization (TACE)|DRUG: Doxorubin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Protracted Temozolomide in Patients With Progressive High Grade Glioma
Status: COMPLETED
Conditions: Glioblastoma|Astrocytoma|Oligodendroglioma|Brain Tumor, Recurrent
Interventions: DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TBTC Study 25PK: Intensive Pharmacokinetic Study of Three Doses of Rifapentine and 25-Desacetyl Rifapentine
Status: COMPLETED
Conditions: Tuberculosis
Interventions: DRUG: Rifapentine|DRUG: 25-desacetyl Rifapentine|DRUG: Isoniazid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Study of Alpelisib and Fulvestrant to Treat Endometrial Cancer
Status: RECRUITING
Conditions: Endometroid Endometrial Cancer
Interventions: DRUG: Alpelisib Pill|DRUG: Fulvestrant injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Duration of hSBA Response After a Primary Series of Bivalent rLP2086 Followed by a Booster Dose
Status: COMPLETED
Conditions: Meningococcal Infection
Interventions: PROCEDURE: blood sampling|DRUG: bivalent rLP2086
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: OTHER
Clinical trial: Cardiovascular Risk Comparison Between Expanded Hemodialysis Using Theranova and On-line Hemodiafiltration
Status: COMPLETED
Conditions: Kidney Failure, Chronic|Renal Dialysis
Interventions: DEVICE: Theranova|DEVICE: Online hemodiafiltration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of Clopidogrel on the Pharmacodynamics and Safety of Terbogrel in Healthy Male Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Terbogrel|DRUG: Clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Closed Incisional Negative Pressure Wound Therapy in Post-surgical Wound Care of Patients With Periprosthetic Joint Infection
Status: RECRUITING
Conditions: Wound Heal|Periprosthetic Joint Infection
Interventions: DEVICE: PREVENA incision management system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Sofpironium Bromide in Subjects With Axillary Hyperhidrosis (BBI-4000-CL-301)
Status: COMPLETED
Conditions: Axillary Hyperhidrosis
Interventions: DRUG: Sofpironium Bromide Gel, 15%|DRUG: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized Clinical Trial To Study Losartan On Endothelial Dysfunction and Insulin Resistance In Obese Patients
Status: COMPLETED
Conditions: Obesity|Hypertension|Hyperglycemia
Interventions: DRUG: losartan|DRUG: Placebo control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Clinical Trial of YYC301 for Treatment of Osteoarthritis of the Knee
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: DRUG: Celecoxib 200mg|DRUG: Tramadol 37.5Mg+ Celecoxib 200mg|DRUG: Tramadol 75mg+ Celecoxib 200mg|DRUG: Tramadol 150mg+ Celecoxib 200mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Rituximab, Gemcitabine, and Vinorelbine in Treating Patients With Hodgkin Lymphoma That Has Relapsed or Not Responded to Treatment
Status: WITHDRAWN
Conditions: Lymphoma
Interventions: BIOLOGICAL: rituximab|DRUG: gemcitabine hydrochloride|DRUG: vinorelbine ditartrate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment for Chronic Pain in Patients With Advanced Cancer
Status: COMPLETED
Conditions: Chronic Myeloproliferative Disorders|Leukemia|Lymphoma|Multiple Myeloma and Plasma Cell Neoplasm|Myelodysplastic Syndromes|Pain|Precancerous/Nonmalignant Condition|Small Intestine Cancer|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: dextromethorphan hydrobromide|DRUG: morphine sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Itraconazole Oral Absorption
Status: COMPLETED
Conditions: Fungal Infection
Interventions: DRUG: fast itraconazole tablet|DRUG: medium itraconazole tablet|DRUG: slow itraconazole tablet|DRUG: oral itraconazole solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: JKB-121 for the Treatment of Nonalcoholic Steatohepatitis
Status: COMPLETED
Conditions: Nonalcoholic Steatohepatitis
Interventions: DRUG: JKB-121: 5 mg twice daily|DRUG: JKB-121: 10 mg twice daily|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of JNJ-75276617 in Combination With Conventional Chemotherapy for Pediatric and Young Adult Participants With Relapsed/Refractory Acute Leukemias
Status: WITHDRAWN
Conditions: Acute Leukemias|Acute Myeloid Leukemia|Acute Lymphoblastic Leukemia|Acute Leukemia of Ambiguous Lineage
Interventions: DRUG: JNJ-75276617|DRUG: Fludarabine|DRUG: Cytarabine|DRUG: Intrathecal Chemotherapy|DRUG: Dexamethasone|DRUG: Vincristine|DRUG: Pegaspargase
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT