pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Wound Dressings for Pemphigus and Pemphigoid
Status: UNKNOWN
Conditions: Pemphigus|Pemphigoid
Interventions: DEVICE: Cotton gauze with petrolatum|DEVICE: Cellulose acetate with petrolatum|DEVICE: Nanocrystalline silver (Acticoat)|DEVICE: Carboxymethylcellulose with ionic silver (Aquacel Ag)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Combination of ATRA and Eltrombopag as the Treatment of Steroid-resistant/Relapse ITP Based on MSC-C5b-9
Status: RECRUITING
Conditions: Purpura, Thrombocytopenic, Idiopathic
Interventions: DRUG: all-trans retinoic acid|DRUG: Eltrombopag
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Intrathecal Dexmedetomidine as an Adjuvant to Low Dose Hyperbaric 0.5% Bupivacaine
Status: COMPLETED
Conditions: Post Operative Pain
Interventions: DRUG: Bupivacain 0.5%|DRUG: Dexmedetomidine Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy and Safety of SYN-010 in IBS-C
Status: TERMINATED
Conditions: Irritable Bowel Syndrome With Constipation
Interventions: DRUG: SYN-010 21 mg|DRUG: SYN-010 42 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Prospective Randomized Double Blinded Controlled Trial of Non-Operative Management of TFCC Injuries
Status: UNKNOWN
Conditions: Wrist Injuries|PRP
Interventions: PROCEDURE: Platelet-rich plasma (PRP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Validation Through Analytical Study With Urine Samples to Compare the Effectiveness and Security of an Intelligent Device
Status: UNKNOWN
Conditions: Renal Insufficiency, Chronic|Heart Failure|Diabete Mellitus|Diabetes; Nephropathy (Manifestation)|Hematuria|Urinary Tract Infections
Interventions: DEVICE: Lab Gold Standard|DEVICE: S-There
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Donor Virus-Specific CMV or AdV CTL to Treat CMV or AdV Reactivation or Disease After Solid Organ or HCT
Status: RECRUITING
Conditions: Allogeneic Hematopoietic Stem Cell Transplantation Recipient|Cytomegalovirus|Donor|Solid Organ Transplantation Recipient|Adenovirus
Interventions: BIOLOGICAL: Allogeneic Cytomegalovirus-Specific Cytotoxic T lymphocytes|BIOLOGICAL: Allogeneic Adenovirus-specific Cytotoxic T Lymphocytes
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Battlefield Acupuncture and Physical Therapy Versus Physical Therapy Alone After Shoulder Surgery
Status: COMPLETED
Conditions: Opioid Use|Pain, Postoperative|SLAP Lesion|Bankart Lesion|Subacromial Impingement Syndrome|Rotator Cuff Tear|Glenohumeral Dislocation|Glenohumeral Subluxation|Hill Sach Lesion|Bony Bankart Lesion|Acromioclavicular Separation
Interventions: DEVICE: Battlefield Acupuncture|PROCEDURE: Post-surgical shoulder protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 0.9% NaCl/Dextrose 5% vs 0.45% NaCl/Dextrose 5% as Maintenance Intravenous Fluids in Hospitalized Children
Status: COMPLETED
Conditions: Hyponatremia
Interventions: DRUG: Hypotonic (0.45% NaCl/5% dextrose) IV maintenance fluids|DRUG: Isotonic (0.9% NaCl/5% dextrose) IV maintenance fluids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Outcomes for Chronic Obstructive Pulmonary Disease Moderate Exacerbators Initiating Treatment
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Fluticasone Propionate / Salmeterol Xinafoate Combination (FSC)|DRUG: Anticholinergics (AC)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Guanfacine for the Treatment of Hyperactivity in Pervasive Developmental Disorder
Status: COMPLETED
Conditions: Pervasive Development Disorders
Interventions: OTHER: placebo|DRUG: extended-release guanfacine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Factors Associated to the Instability of the INR (International Normalized Ratio ) in the Prevention of Thromboembolism AVK (Anti Vitamin K) in Atrial Fibrillation in the Elderly: Instead of Comorbidities
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: OTHER: Charlson comorbidity index
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Evaluate the Safety and Tolerability of BMS-986408 Alone and in Combination With Nivolumab or Nivolumab and Ipilimumab in Participants With Advanced Solid Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Solid Tumors
Interventions: DRUG: BMS-986408|BIOLOGICAL: Nivolumab|BIOLOGICAL: Ipilimumab|BIOLOGICAL: Platinum-doublet chemotherapy|DRUG: Rabeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Postoperative Adjuvant Chemotherapy in Early-stage Cervical Cancer That Not Meet Criteria of Adjuvant Therapeutic According to NCCN Guideline
Status: RECRUITING
Conditions: Uterine Cervical Neoplasms|Cervical Cancer
Interventions: DRUG: Paclitaxel or docetaxel + Cisplatin or carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Doxycycline Verses Placebo for the Treatment of Severe Nonproliferative or Mild or Moderate Proliferative Diabetic Retinopathy
Status: COMPLETED
Conditions: Diabetic Retinopathy
Interventions: DRUG: doxycycline monohydrate|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Treat Stroke to Target
Status: COMPLETED
Conditions: Ischemic Stroke|Transient Ischemic Attack|Atherosclerotic Stenosis
Interventions: PROCEDURE: Target : 100 mg/dL (+/-10 mg/dL)|PROCEDURE: 70 mg/dL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of Carboplatin + Paclitaxel and MK0683 in Patients With Chemotherapy-naive Non-Small Cell Lung Cancer (NSCLC)(0683-066)
Status: TERMINATED
Conditions: Neoplasms
Interventions: DRUG: MK0683, vorinostat
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Progestin-Induced Withdrawal Bleed on Ovulation Induction Cycles With Clomiphene Citrate
Status: WITHDRAWN
Conditions: Polycystic Ovary Syndrome|Infertility
Interventions: DRUG: Progestin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Arteriovenous Fistula Maturation Evaluation Study. FAME Study
Status: COMPLETED
Conditions: End-stage Renal Disease|Hemodialysis Access Failure|Vascular Access Maturation|Native Arteriovenous Fistula
Interventions: DIAGNOSTIC_TEST: Doppler ultrasound study
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of CO2 Laser on Enamel White Spot Lesion Formation Around Orthodontic Brackets
Status: COMPLETED
Conditions: White Spot Lesion
Interventions: RADIATION: CO2 laser irradiation|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: the Effect of Different Oxaliplatin Dose in Transarterial Infusion (TAI) in Unresectable Hepatocellular Carcinoma
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma
Interventions: PROCEDURE: transarterial infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimize Astronaut Sleep Medication Efficacy and Individual Effects
Status: COMPLETED
Conditions: Sleep|Cognition|Pharmacologic Actions
Interventions: DRUG: Zolpidem
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Clinical Trial of Elemene Injection/Elemene Oral Emulusion in Combination With the Best Supportive Treatment in the Treatment of Advanced Primary Liver Cancer
Status: UNKNOWN
Conditions: Advanced Primary Liver Cancer
Interventions: DRUG: Elemene Injection/Elemene Oral Emulusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effects of Azilsartan on Coronary Artery Plaque in Essential Hypertensive Patients With Stable Angina and Dyslipidemia.
Status: WITHDRAWN
Conditions: Essential Hypertension With Stable Angina and Dyslipidemia
Interventions: DRUG: Azilsartan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of Respiratory Gases Conditioning on Aerosol Delivery During Invasive Ventilation
Status: COMPLETED
Conditions: Brain Injuries, Traumatic
Interventions: DEVICE: Aerogen Solo®|DEVICE: Heated-humidified circuit|DEVICE: Heated-humidified circuit|DEVICE: Dry ventilator circuit specific for aerosol therapy|DEVICE: Conventional dry ventilator circuit with HME filter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pilot Study Comparing Diagnostic Imaging Versus Tomosynthesis in Detection of Hip, Wrist or Tibia Injury
Status: TERMINATED
Conditions: Wrist Injury|Tibial Fracture|Hip Injury
Interventions: DEVICE: Standard X-Ray + CT|DEVICE: Standard X-Ray + MRI|DEVICE: TOMO
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Enhancing Neonatal Sucking Reflex: A Study on the Efficacy of Magnesium Sulphate in Severe Birth Asphyxia
Status: COMPLETED
Conditions: Birth Asphyxia
Interventions: DRUG: Magnesium Sulphate infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Remote Alcohol Monitoring to Facilitate Abstinence Reinforcement: Feasibility
Status: COMPLETED
Conditions: Alcohol Use Disorder
Interventions: BEHAVIORAL: Contingency management: Contingent incentives|BEHAVIORAL: Contingency management: Noncontingent incentives
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Acupuncture at Acupoints Group Around the Base of Skull for Post-Stroke Depression
Status: RECRUITING
Conditions: Post-stroke Depression
Interventions: DEVICE: Electroacupuncture|DEVICE: Sham acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Concomitant Administration of a New Hexavalent Vaccine With a Meningococcal Serogroup C Conjugate Vaccine in Healthy Infants During Primary Series Immunisation Followed by Booster Vaccination
Status: COMPLETED
Conditions: Neisseria Meningitidis|Bacterial Infections|Virus Diseases
Interventions: BIOLOGICAL: Hexavalent vaccine|BIOLOGICAL: NeisVac-C|BIOLOGICAL: Prevenar 13|BIOLOGICAL: RotaTeq|BIOLOGICAL: Nimenrix|BIOLOGICAL: M-M-RVAXPRO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Acai Berry Consumption on Blood Glucose Levels in Healthy Adults
Status: COMPLETED
Conditions: Post-prandial Glycaemia
Interventions: DIETARY_SUPPLEMENT: Acai smoothie|DIETARY_SUPPLEMENT: Placebo smoothie
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Preventive Physiotherapy Practices on Posture and Work-Related Functions in Office Workers
Status: COMPLETED
Conditions: Work-related Musculoskeletal Disorders|Office Workers
Interventions: BEHAVIORAL: Supervised EMG Biofeedback Exercise Training Group|BEHAVIORAL: Home-Based Exercise Training Group|BEHAVIORAL: Posture Training/Ergonomic Regulations Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Heart of the Family: A Cardiovascular Disease and Type 2 Diabetes Risk Reduction Intervention in High-Risk Rural Families
Status: RECRUITING
Conditions: Diabetes Mellitus, Type 2|Cardiovascular Diseases
Interventions: BEHAVIORAL: Active Control Intervention educational sessions|BEHAVIORAL: Family Dyad Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Randomized Control Trial Comparing CMPAT and MAT for Lumbar Puncture
Status: RECRUITING
Conditions: a Randomized Controlled Trial
Interventions: PROCEDURE: Computerized Modified Paramedian Approach Technique|PROCEDURE: Conventional Midline Approach Technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: High Dose Vitamin D Plus Multivitamin in the Prevention of Cluster Headache
Status: TERMINATED
Conditions: Cluster Headache
Interventions: DRUG: Vitamin D|DRUG: multivitamin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: GBS-NN/NN2 (50 µg of Each Fusion Protein [GBS-NN and GBS-NN2] in Combination With 500 µg Aluminum as Alhydrogel®) Given With and Without the Tdap Vaccine in Healthy Non-pregnant Women 18 to 49 Years of Age
Status: NOT_YET_RECRUITING
Conditions: Streptococcus Agalactiae Infection
Interventions: DRUG: GBS-NN/NN2 vaccine|DRUG: Tdap vaccine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of Duloxetine in Participants With Chronic Pain Due to Osteoarthritis in China
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DRUG: Duloxetine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of an Inherited Ventricular Arrhythmia
Status: RECRUITING
Conditions: Catecholaminergic Polymorphic Ventricular Tachycardia Type 1
Interventions: DRUG: S48168 (ARM210)|DRUG: Matching Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Photodynamic Therapy Using HPPH in Treating Patients With Advanced Non-Small Cell Lung Cancer That Blocks the Air Passages
Status: TERMINATED
Conditions: Lung Cancer
Interventions: DRUG: HPPH|PROCEDURE: endoscopic procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ReCLAIM-2 Study to Evaluate Safety,Efficacy & Pharmacokinetics of Elamipretide in Subjects With AMD With Non-central GA
Status: COMPLETED
Conditions: Age-related Macular Degeneration
Interventions: COMBINATION_PRODUCT: Subcutaneous elamipretide through the elamipretide delivery system|COMBINATION_PRODUCT: Subcutaneos placebo through the elamipretide delivery system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Pulsed Electromagnetic Field Therapy on Patients With Low Back Pain
Status: UNKNOWN
Conditions: Low Back Pain
Interventions: DEVICE: MDCure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Postoperative Abdominal Binder to Improve Outcomes After Incisional Hernia Repair
Status: WITHDRAWN
Conditions: Incisional Hernia
Interventions: DEVICE: Abdominal binder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of Two Doses of Oral Cholera Vaccine (Shanchol™) in Subjects Aged 1 Year and Older in the Philippines
Status: COMPLETED
Conditions: Cholera
Interventions: BIOLOGICAL: Shanchol™: Oral Cholera Vaccine Killed Bivalent (O1 and O139) Whole Cell|BIOLOGICAL: Shanchol™: Oral Cholera Vaccine Killed Bivalent (O1 and O139) Whole Cell|BIOLOGICAL: Shanchol™: Oral Cholera Vaccine Killed Bivalent (O1 and O139) Whole Cell
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Outcomes After Secondary Cytoreductive Surgery With or Without Carboplatin Hyperthermic Intraperitoneal Chemotherapy (HIPEC) Followed by Systemic Combination Chemotherapy for Recurrent Platinum-Sensitive Ovarian, Fallopian Tube, or Primary Peritoneal Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Ovarian Cancer|Fallopian Tubes Cancer|Peritoneal Cancer
Interventions: PROCEDURE: Secondary Cytoreductive Surgery|DRUG: Carboplatin Hyperthermic Intraperitoneal Chemotherapy (HIPEC)|DRUG: platinum-based systemic chemotherapy postoperatively|DRUG: platinum-based systemic chemotherapy postoperatively
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study of Robot-assisted Therapy for Post-stroke Forearm and Wrist Rehabilitation Training
Status: COMPLETED
Conditions: Stroke
Interventions: DEVICE: Robot-assisted therapy for wrist and forearm|OTHER: Standard rehabilitation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intra-operative Uterosacral Ligament Bupivacaine Injection During Minimally Invasive Hysterectomy
Status: COMPLETED
Conditions: Pain, Postoperative|Opioid Use
Interventions: DRUG: Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Augment® Bone Graft (Formerly GEM OS™1 Bone Graft) Compared to Autologous Bone Graft in Foot and Ankle Fusions
Status: COMPLETED
Conditions: Foot Fusion
Interventions: DEVICE: Augment® Bone Graft|PROCEDURE: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lesinurad Tablet Bioequivalence
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Lesinurad 400 mg (manufactured at Site 1)|DRUG: Lesinurad 400 mg (manufactured at Site 2)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of VXCO-100, a SARS-CoV Candidate Vaccine, in Adults in the Republic of South Africa
Status: ACTIVE_NOT_RECRUITING
Conditions: SARS-CoV|SARS-CoV-2
Interventions: BIOLOGICAL: VXCO-100|BIOLOGICAL: COVID-19 mRNA vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: First-in-man Trial Examining the Safety and Efficacy of BuMA Supreme and Resolute Integrity in Patients With de Novo Coronary Artery Stenosis
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DEVICE: BuMA Supreme Biodegradable drug coating coronary stent system|DEVICE: Resolute Integrity durable polymer stent system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Women's MoonShot: Neoadjuvant Treatment With PaCT for Patients With Locally Advanced TNBC
Status: ACTIVE_NOT_RECRUITING
Conditions: Stage I Breast Cancer AJCC v7|Stage IA Breast Cancer AJCC v7|Stage IB Breast Cancer AJCC v7|Stage II Breast Cancer AJCC v6 and v7|Stage IIA Breast Cancer AJCC v6 and v7|Stage IIB Breast Cancer AJCC v6 and v7|Stage III Breast Cancer AJCC v7|Stage IIIA Breast Cancer AJCC v7|Stage IIIB Breast Cancer AJCC v7|Stage IIIC Breast Cancer AJCC v7|Triple-Negative Breast Carcinoma
Interventions: DRUG: Carboplatin|DRUG: Paclitaxel|BIOLOGICAL: Panitumumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Incontinence Program Applied to Obese Elderly on Quality of Life, Coping and Loneliness
Status: NOT_YET_RECRUITING
Conditions: Obesity, Primary|Incontinence, Urge|Incontinence Stress|Aging
Interventions: BEHAVIORAL: improving quality of life, coping with urinary incontinence and kegel exercise training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Cefepime Continuous Infusion Versus an Intermittent Dosing Regimen
Status: COMPLETED
Conditions: Sepsis|Bacteremia
Interventions: DRUG: cefepime|DRUG: cefepime
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of MEDI5395 in Combination With Durvalumab in Participants With Select Advanced Solid Tumors
Status: COMPLETED
Conditions: Advanced Solid Tumors
Interventions: BIOLOGICAL: MEDI5395|BIOLOGICAL: Durvalumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Oral Versus Enteral Nutrition After Pancreatoduodenectomy
Status: UNKNOWN
Conditions: Pancreatic Cancer|Cancer of the Duodenum|Cholangiocarcinoma|Chronic Pancreatitis
Interventions: OTHER: Enteral nutrition|OTHER: Oral nutrition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Microbiome in Immunotherapy naïve NSCLC Patients Receiving PD-1/L1 Blockade (MIP_NSCLC)
Status: RECRUITING
Conditions: NSCLC Stage IV|NSCLC, Recurrent
Interventions: DIAGNOSTIC_TEST: Microbiome
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Dental Implant Placement in Adjunction With Autologous Alveolar Bone-Marrow Derived Mesenchymal Stem Cells (aBM-MSCs)
Status: COMPLETED
Conditions: Implant Therapy
Interventions: BIOLOGICAL: Biocomplex: aBM-MSCs/fibrin glue/collagen fleece|PROCEDURE: Two-stage surgical implant placement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Changes in Metabolic Activity, and Gait Function by Dual-task Cognitive Game-based Treadmill Intervention in Parkinson's Disease.
Status: UNKNOWN
Conditions: Parkinson Disease
Interventions: OTHER: Game based treadmill Program|OTHER: Conventional Gait Rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Great Beginnings for Healthy Native Smiles: An Early Childhood Caries Prevention Project
Status: TERMINATED
Conditions: Early Childhood Caries|Dental Caries
Interventions: BEHAVIORAL: Oral Health|BEHAVIORAL: Healthy Lifestyle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Israel Multicenter D-Serine Study (IMSER) for the Treatment of Schizophrenia
Status: UNKNOWN
Conditions: Schizophrenia|Schizoaffective Disorder
Interventions: DRUG: D-serine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Cardiometabolic Disease and Pulmonary Hypertension
Status: TERMINATED
Conditions: Obesity
Interventions: DRUG: Metformin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Evaluation of Approved Weight-Based Dose Compared to Fixed Dose of Plerixafor in Patients With Non-Hodgkin's Lymphoma (NHL) Weighing Less Than 70 Kilograms
Status: COMPLETED
Conditions: Non-Hodgkin's Lymphoma
Interventions: DRUG: Granulocyte-colony stimulating factor (G-CSF)|DRUG: Fixed Dose Plerixafor|DRUG: Weight-Based Plerixafor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Breakfast Rise, Education and Knowledge Study
Status: COMPLETED
Conditions: type1diabetes
Interventions: OTHER: High glycaemic load breakfast meal|OTHER: High glycaemic load breakfast meal with additional 10g protein|OTHER: Medium glycaemic load breakfast meal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Cocoa Supplementation, Inflammaging, and Epigenetic Aging
Status: UNKNOWN
Conditions: Aging|Inflammation|Cardiovascular Diseases
Interventions: DIETARY_SUPPLEMENT: Cocoa extract|DIETARY_SUPPLEMENT: Multivitamin|DIETARY_SUPPLEMENT: Cocoa extract placebo|DIETARY_SUPPLEMENT: Multivitamin placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Bacillus Subtilis in Parkinson's Disease
Status: RECRUITING
Conditions: Parkinson Disease
Interventions: DIETARY_SUPPLEMENT: Bacillus Subtilis|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Open-label, Phase II Study of MLN9708 in Patients With Relapsed/Refractory Cutaneous and Peripheral T-cell Lymphomas
Status: COMPLETED
Conditions: Lymphoma, T-Cell
Interventions: DRUG: MLN9708
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Mycophenolate Mofetil and Cyclophosphamide for Active Takayasu's Arteritis
Status: COMPLETED
Conditions: Takayasu Arteritis
Interventions: DRUG: MMF|DRUG: CYC|DRUG: Glucocorticoids|DRUG: MTX|DRUG: AZA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hypertension Patients on Drug Medication Adherence and Rational Medication Use
Status: COMPLETED
Conditions: Hypertension Patients
Interventions: OTHER: Education and Telephone Counceling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Dose Escalation Study of PF-07209326 in Healthy Participants and Participants With Sickle Cell Disease
Status: COMPLETED
Conditions: Healthy|Sickle Cell Anemia
Interventions: BIOLOGICAL: Placebo|BIOLOGICAL: PF-07209326|BIOLOGICAL: PF-07209326
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of Diosmin for the Treatment of Digital Ulcers in Systemic Sclerosis
Status: NOT_YET_RECRUITING
Conditions: Scleroderma, Systemic|Digital Ulcer
Interventions: COMBINATION_PRODUCT: Diosmin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Radiation Dose Intensification With Accelerated Hypofractionated Intensity Modulated Radiation Therapy and Concurrent Carboplatin and Paclitaxel for Inoperable Esophageal Cancer
Status: RECRUITING
Conditions: Esophagus Cancer|Esophageal Cancer|Cancer of the Esophagus
Interventions: RADIATION: Intensity Modulated Radiation Therapy|DRUG: Carboplatin|OTHER: MD Anderson Symptom Inventory (MDASI)-Plus module|OTHER: EuroQol (EQ-5D)|OTHER: SF-12|OTHER: MOS Social Support Measure|OTHER: CES-D|PROCEDURE: Blood for ctDNA (optional)|PROCEDURE: Blood for SCCA|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Confocal Raman Spectroscopy: in Vivo Measurement of Physiological Skin Parameters
Status: COMPLETED
Conditions: Dermatologic Disorders|Disorder of Cholesterol Metabolism
Interventions: PROCEDURE: Venous blood collection|PROCEDURE: Raman spectroscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Effects of Nutritional Supplementation on Protein and Energy Homeostasis in Malnourished Chronic Hemodialysis Patients
Status: COMPLETED
Conditions: End Stage Renal Disease
Interventions: DIETARY_SUPPLEMENT: nutritional supplement|DRUG: recombinant human growth hormone (rcGH)|BEHAVIORAL: exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Manganese-Enhanced Magnetic Resonance Imaging of MyOcardial injuRY in COVID 19 (COVID-19)
Status: COMPLETED
Conditions: Covid19
Interventions: DIAGNOSTIC_TEST: Cardiac MRI|DIAGNOSTIC_TEST: Cardiac CT|DIAGNOSTIC_TEST: Electrocardiogram (ECG)|DIAGNOSTIC_TEST: Blood samples
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: DORADO-AC-EX - A Long-Term Safety Extension Study to the Phase 3 DORADOC-AC Study (Protocol DAR-312) of Darusentan in Resistant Hypertension
Status: TERMINATED
Conditions: Hypertension
Interventions: DRUG: Darusentan|DRUG: Guanfacine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety/Efficacy of Sitagliptin in Patient w/ Type 2 Diabetes (0431-801)
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Sitagliptin|DRUG: Comparator: Rosiglitazone|DRUG: Comparator: Placebo|DRUG: Comparator: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Inspiratory Muscle Training on Duration of Mechanical Ventilation Support
Status: COMPLETED
Conditions: Respiratory Failure
Interventions: OTHER: IMST|OTHER: Sham IMST
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Antineoplaston Therapy in Treating Patients With Primary Malignant Brain Tumors
Status: COMPLETED
Conditions: Malignant Brain Tumors
Interventions: DRUG: Antineoplaston therapy (Atengenal + Astugenal)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Rituximab in the First Episode of Pediatric Idiopathic Nephrotic Syndrome
Status: COMPLETED
Conditions: Steroid-Sensitive Nephrotic Syndrome
Interventions: DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Instillation and Packing in Mydriasis for Premature Infants
Status: COMPLETED
Conditions: Preterm Infants
Interventions: DRUG: 1% tropicamide and 2.5% phenylephrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Radiation Therapy With or Without Goserelin in Treating Patients Who Have Undergone Surgery for Recurrent or Refractory Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: goserelin acetate|PROCEDURE: adjuvant therapy|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Vitamin D Supplementation on Disease Activity Markers in Systemic Lupus Erythematosus (SLE)
Status: COMPLETED
Conditions: Systemic Lupus Erythematosus
Interventions: DRUG: vitamin D 25(OH)D|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effectiveness and Safety of RXI 109 on the Outcome of Scar Revision Surgery in Healthy Adults
Status: COMPLETED
Conditions: Hypertrophic Scar
Interventions: DRUG: RXI-109|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: NK Cells Infusions With Irinotecan, Temozolomide, and Dinutuximab
Status: RECRUITING
Conditions: Relapsed Neuroblastoma|Refractory Neuroblastoma
Interventions: BIOLOGICAL: Natural Killer Cells|DRUG: Temozolomide|DRUG: Irinotecan|DRUG: Dinutuximab|DRUG: Sargramostim
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anoplasty for Post Hemorroidectomy Anal Stenosis : Diamond Versus V-Y Flap Techniques
Status: UNKNOWN
Conditions: Anoplasty in Treatment of Post Hemorroidectomy Anal Stenosis
Interventions: PROCEDURE: anoplasty in treatment of post hemorroidectomy anal stenosis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Fitbit One and Text Messaging Prompts to Promote Physical Activity in Overweight/Obese Adults
Status: COMPLETED
Conditions: Health Behavior|Obesity
Interventions: BEHAVIORAL: SMS Text Messages & Fitbit One|BEHAVIORAL: Fitbit One Only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of NCX4016 on Walking Distance in Patients With Peripheral Arterial Occlusive Disease (PAOD)
Status: COMPLETED
Conditions: Intermittent Claudication
Interventions: DRUG: NCX-4016|DRUG: NCX4016 placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Palliative Radiofrequency Ablation in Metastatic Renal Cell Carcinoma Patients
Status: COMPLETED
Conditions: Carcinoma, Renal Cell
Interventions: PROCEDURE: Radiofrequency ablation; Interferon-alpha|PROCEDURE: Radiofrequency ablation; Sunitinib maleate|DRUG: Sunitinib maleate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non-Myeloablative Allogeneic Stem Cell Transplantation With Matched Unrelated Donors for Treatment of Hematologic Malignancies, Renal Cell Carcinoma, and Aplastic Anemia
Status: COMPLETED
Conditions: Acute Myeloid Leukemia|Myelodysplasia|Acute Lymphoblastic Leukemia|Chronic Lymphocytic Leukemia|Follicular Lymphoma|Multiple Myeloma|NHL|Myeloproliferative Diseases|Chronic Myeloid Leukemia|Renal Cell Carcinoma|Aplastic Anemia
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Accelerated Development of Additive Pharmacotherapy Treatment (ADAPT-2) for Methamphetamine Use Disorder
Status: COMPLETED
Conditions: Methamphetamine Use Disorder
Interventions: DRUG: Naltrexone: Vivitrol®|DRUG: Placebo (PLB) Injectable|DRUG: Bupropion: Wellbutrin XL®|DRUG: Placebo (PLB) Oral
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The PENG Block in Elective Hip Surgery and Its Effect on Postoperative Pain and Length of Stay.
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: PROCEDURE: PENG block|PROCEDURE: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: CAR-37 T Cells In Hematologic Malignancies
Status: COMPLETED
Conditions: Hematologic Malignancy|Leukemia|Lymphoma|Lymphoma, B-Cell|Lymphoma, T-Cell|Lymphoma, Non-Hodgkin
Interventions: BIOLOGICAL: CAR-37 T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MC5-A Scrambler Therapy for the Treatment of Chronic Neuropathic Extremity Pain
Status: UNKNOWN
Conditions: Peripheral Neuropathy|Low Back Pain
Interventions: DEVICE: MC5-A Scrambler Therapy|DEVICE: MC5-A Scrambler Therapy Sham Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Angiotensin II Receptor Blockers (ARB) on Left Ventricular Reverse Remodelling After Aortic Valve Replacement in Severe Valvular Aortic Stenosis
Status: UNKNOWN
Conditions: Aortic Valve Stenosis|Left Ventricular Hypertrophy|Atrial Fibrillation
Interventions: DRUG: Candesartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Vibrant Capsule vs. Vibrant Placebo for the Treatment of Chronic Idiopathic Constipation (CIC)
Status: COMPLETED
Conditions: Chronic Idiopathic Constipation
Interventions: DEVICE: Vibrant capsule|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Polyphenols, Prebiotics, the Gut Microbiome and Stress
Status: COMPLETED
Conditions: Stress, Psychological|Gut Bacteria
Interventions: DIETARY_SUPPLEMENT: Blueberry, cranberry, green tea extract, cocoa|DIETARY_SUPPLEMENT: GOS, Inulin, RS2|DIETARY_SUPPLEMENT: prebiotics and polyphenols|DIETARY_SUPPLEMENT: Maltodextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Pilot Study of Melatonin and Epilepsy
Status: COMPLETED
Conditions: Epilepsy
Interventions: DRUG: Melatonin|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Investigation of Neural Stem Cells in Ischemic Stroke
Status: TERMINATED
Conditions: Ischemic Stroke|Chronic Stroke|Hemiparesis|Arm Paralysis
Interventions: COMBINATION_PRODUCT: CTX0E03 Drug Product and delivery device|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hemodynamic and Ventilatory Responses to Head-down Postural Drainage Position
Status: COMPLETED
Conditions: Traumatic Blunt Chest and/or Blunt Abdominal Injury
Interventions: OTHER: Head down 30 degree postural drainage position|OTHER: Horizontal supine lying
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Gemcitabine Plus Ascorbate for Sarcoma in Adults
Status: TERMINATED
Conditions: Sarcoma|Soft Tissue Sarcoma|Unresectable Soft Tissue Sarcoma|Metastatic Bone Tumor|Bone Sarcoma
Interventions: DRUG: Ascorbate|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Triple Antibiotic Paste With Combination of Chitosan and Calcium Hydroxide as a Root Canal Disinfectant
Status: UNKNOWN
Conditions: Periapical Abscess
Interventions: DRUG: root canal treatment and intracanal medicament
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clitoral Therapy Device in Alleviating Sexual Dysfunction After Genital Mutilation.
Status: UNKNOWN
Conditions: Sexual Dysfunction|Sexual Arousal Disorder
Interventions: DEVICE: EROS device|BEHAVIORAL: Psychosexual support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Fimasartan on Insulin Secretion in Type 2 Diabetic Patients
Status: COMPLETED
Conditions: Diabetes Mellitus|Hypertension
Interventions: DRUG: Fimasartan|DRUG: Amlodipine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of a Nutritional Blend to Prevent Cognitive Decline in Older Adults
Status: COMPLETED
Conditions: Cognitive Decline
Interventions: DIETARY_SUPPLEMENT: Nutrional blend of ingredients including vitamins and fish oil|DIETARY_SUPPLEMENT: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Examine the Effect of Daridorexant on the Way the Body Absorbs, Distributes, and Gets Rid of Dabigatran and Rosuvastatin in Healthy Male Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Dabigatran etexilate|DRUG: Rosuvastatin|DRUG: Daridorexant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effect of Pre-surgery Neuromuscular Physiotherapy (PT)
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: OTHER: preoperative neuromuscular training|BEHAVIORAL: knee OA School
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prescription of Physical Exercise Through Mobile Application in Elderly
Status: COMPLETED
Conditions: Motor Activity|Aerobic Exercise|Mobile Applications|Aged|Prescriptions|Cell Phones|Resistance Training|Muscle Strenght
Interventions: OTHER: Training group|OTHER: Mobile group|OTHER: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Niche In CEsarean Scar Trial (NICEST)
Status: RECRUITING
Conditions: Niche
Interventions: PROCEDURE: Double-layer uterine closure|PROCEDURE: Single-layer uterine closure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study Testing if Medicine Can Make Pigment Epithelium Detachments Regress and Stabilize the Vision in Eyes
Status: TERMINATED
Conditions: Macular Degeneration|Retinal Detachment
Interventions: DRUG: Aflibercept|DRUG: Verteporfin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Impact of Perioperative Geriatric Care on Outcomes After Elective Noncardiac Surgery
Status: COMPLETED
Conditions: SURGICAL PROCEDURES, OPERATIVE|Aged|Epidemiology|Mortality
Interventions: PROCEDURE: Preoperative geriatric consult or assessment|PROCEDURE: No Preoperative geriatric consult or assessment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Impact of Mobile Phone Application Use on Adult BLS
Status: RECRUITING
Conditions: Out-Of-Hospital Cardiac Arrest|Mobile Phone Use|Stress|Knowledge, Attitudes, Practice
Interventions: DEVICE: MOBI-CPR game
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of the Impact of Trans Fatty Acids From Dairy Products on Cardiovascular Risk Factors
Status: COMPLETED
Conditions: Cardiovascular Disease
Interventions: OTHER: Ruminant trans fats
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Treatment of Peritoneal Carcinomatosis With Pressurized IntraPeritoneal Aerosol Chemotherapy -
Status: COMPLETED
Conditions: Peritoneum; Carcinomatosis|Peritoneal Neoplasms|Peritoneal Metastases|Chemotherapy Effect|Chemotherapeutic Toxicity|Quality of Life|Histologic Progression
Interventions: DRUG: PIPAC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fostamatinib for the Treatment of Lower-risk Myelodysplastic Syndromes or Chronic Myelomonocytic Leukemia Who Have Failed Therapy With Hypomethylating Agents
Status: COMPLETED
Conditions: Refractory Chronic Myelomonocytic Leukemia|Refractory Myelodysplastic Syndrome
Interventions: DRUG: Fostamatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Teaching: Individual to Increase Adherence to Therapeutic Regimen in Hypertension Arterial and/or Diabetes Type 2
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Hypertension
Interventions: BEHAVIORAL: Teaching: Individual (5606)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE