pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Rivaroxaban Pharmacokinetics/Pharmacodynamics (PK/PD) Study in Pediatric Subjects
Status: COMPLETED
Conditions: Venous Thrombosis|Pediatrics
Interventions: DRUG: Rivaroxaban (Xarelto, BAY59-7939)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: CHEmotherapy and Cognitive Deterioration in Patients With Operable Breast Cancer: Impact of Cognitive Rehabilitation (CHEMOFOG)
Status: NOT_YET_RECRUITING
Conditions: Breast Cancer
Interventions: OTHER: Neurotablet® and Neuropsychological evaluations|OTHER: Neuropsychological evaluations
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effects and Safety of Budesonide Inhalation Suspension Via Transnasal Nebulization in Nasal Polyps
Status: COMPLETED
Conditions: Nasal Polyps
Interventions: DRUG: budesonide|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Recombinant Vaccinia Virus to Evaluate the Safety and Efficacy of a Transdermal Injection Within the Tumor of Patients With Primary or Metastatic Hepatic Carcinoma
Status: COMPLETED
Conditions: Neoplasms, Liver
Interventions: GENETIC: JX-594: Recombinant vaccinia virus (TK-deletion plus GM-CSF)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trimethoprim/Sulfamethoxazole Combined With Caspofungin as First-line Therapy in PCP
Status: UNKNOWN
Conditions: Pneumocystis Pneumonia
Interventions: DRUG: caspofungin|DRUG: TMP/SMZ(trimethoprim/sulfisoxazole)|DRUG: Methylprednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cognitive Protective Effect of Newer Antidiabetic Drugs
Status: UNKNOWN
Conditions: Type 2 Diabetes
Interventions: DRUG: Dapagliflozin|DRUG: Empagliflozin|DRUG: Canagliflozin|DRUG: Sitagliptin|DRUG: Saxagliptin|DRUG: Linagliptin|DRUG: Vildagliptin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Language and Motor Skills of Preterm Infants in Pre-school Age: Diagnosis and Early Intervention
Status: COMPLETED
Conditions: Disorder of Speech and Language Development
Interventions: BEHAVIORAL: parental stimulation according to protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Comparison of Three Nebulizers for Standard Clinical and Research Use in Methacholine Challenge Testing
Status: COMPLETED
Conditions: Asthma
Interventions: DEVICE: Wright nebulizer|DEVICE: Bennett-Twin nebulizer|DEVICE: Aeroneb Solo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mid-line Excision Versus Karydakis Operation for Pilonidal Sinus
Status: COMPLETED
Conditions: Pilonidal Sinus
Interventions: PROCEDURE: Surgery for pilonidal disease, midline excision|PROCEDURE: Surgery for pilonidal disease, Karydakis operation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fluorouracil Plus UCN-01 in Treating Patients With Advanced or Refractory Solid Tumors
Status: COMPLETED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: 7-hydroxystaurosporine|DRUG: fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: The Effect of Gluten in Patients With Irritable Bowel Syndrome and Healthy Volunteers
Status: COMPLETED
Conditions: Irritable Bowel Syndrome
Interventions: OTHER: Gluten-free diet with gluten powder|OTHER: Gluten-free diet with placebo powder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Maintenance Therapy of 308-nm Excimer Laser Therapy in Patients With Vitiligo
Status: UNKNOWN
Conditions: Vitiligo|Maintenance Therapy|the 308-nm Excimer Laser|Recurrence
Interventions: DEVICE: the 308-nm excimer laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of S-707106 in Subjects With Type 2 Diabetes Mellitus and Inadequate Glycemic Control With Metformin Therapy
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: S-707106 Dose A|DRUG: S-707106 Dose B|DRUG: S-707106 Dose C|DRUG: Placebo A tablet|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of KYV-101, a CD19 CAR T Cell Therapy, in Participants With Treatment Refractory Progressive Multiple Sclerosis
Status: RECRUITING
Conditions: Progressive Multiple Sclerosis
Interventions: BIOLOGICAL: KYV-101 (Biological) - 0.33 ×10^8 cells|BIOLOGICAL: KYV-101 (Biological) - 1 ×10^8 cells|DRUG: Chemotherapy: cyclophosphamide (CYC)|DRUG: Chemotherapy: fludarabine (FLU)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of L-threo DOPS on Orthostatic Hypotension Symptoms and Other Non-motor Symptoms in Patients With MSA
Status: COMPLETED
Conditions: Multiple System Atrophy
Interventions: DRUG: L-Threo DOPS|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Peer to Peer Mentoring For Individuals With Early Inflammatory Arthritis: An Effectiveness Study (Pilot RCT)- Peer Mentoring Program
Status: COMPLETED
Conditions: Early Inflammatory Arthritis
Interventions: BEHAVIORAL: One-on-one peer support|BEHAVIORAL: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Investigating Speech Sequencing in Neurotypical Speakers and Persons With Disordered Speech
Status: RECRUITING
Conditions: Stuttering, Developmental|Aphasia, Primary Progressive
Interventions: BEHAVIORAL: Learning of non-native phoneme combinations: 6 training sessions|BEHAVIORAL: Learning of non-native phoneme combinations: 1 training session|BEHAVIORAL: Learning of novel multisyllabic nonwords|DEVICE: Anodal tDCS|DEVICE: Sham tDCS|BEHAVIORAL: Learning of non-native phoneme combinations: 8 training sessions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: DAA in the Risk of Recurrence After Curative Treatment of HCC
Status: WITHDRAWN
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Ledipasvir 90mg/Sofosbuvir 400 mg|DRUG: Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effects of Mycophenolate Mofetil (MMF) On Anti-HLA (Human Leukocyte Antigen)Antibody Levels In Patients Awaiting Cadaveric Renal Transplant.
Status: COMPLETED
Conditions: Kidney Failure, Chronic|Diabetic Nephropathies|Glomerulonephritis, IGA|Hypertension, Renal
Interventions: DRUG: mycophenolate mofetil (CellCept)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Misfolded Proteins in the Skin of People With Parkinson's Disease and Other Parkinsonism
Status: RECRUITING
Conditions: Parkinson Disease|Parkinsonism|Dementia With Lewy Bodies|Multiple System Atrophy|Progressive Supranuclear Palsy|Corticobasal Degeneration
Interventions: PROCEDURE: punch skin biopsy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Role of COX-2 Inhibition in Salt Sensitivity of Blood Pressure
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: celecoxib (Celebrex)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Global Registry for COL6-related Dystrophies
Status: RECRUITING
Conditions: Bethlem Myopathy|Ullrich Congenital Muscular Dystrophy 1, Digenic, Col6A1/Col6A2|Ullrich Congenital Muscular Dystrophy 1, Autosomal Recessive|Ullrich Congenital Muscular Dystrophy 1, Autosomal Dominant|Bethlem Myopathy 1, Autosomal Recessive|UCMD|BTHLM1
Interventions: OTHER: Patient Registry
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Artificial Intelligence 3D Augmented Reality Robot-Assisted-Radical- Prostatectomy v.s. no3D Intervention
Status: RECRUITING
Conditions: Cancer of Prostate
Interventions: PROCEDURE: 3D Robot-assisted laparoscopic radical prostatectomy and pelvic lymphadenectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Famciclovir Pediatric Formulation in Children 1 to 12 Years of Age With Herpes Simplex Infection
Status: COMPLETED
Conditions: Herpes Simplex
Interventions: DRUG: Famciclovir
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lenalidomide and Pidilizumab in Treating Patients With Relapsed or Refractory Multiple Myeloma
Status: TERMINATED
Conditions: Multiple Myeloma
Interventions: DRUG: lenalidomide|BIOLOGICAL: pidilizumab|OTHER: pharmacological study|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Cis-9-cetylmyristoleate in Sub-healthy Subjects Presenting With Knee Joint Pain
Status: COMPLETED
Conditions: Knee Pain Intermittent
Interventions: DIETARY_SUPPLEMENT: JOINTRUS®|DIETARY_SUPPLEMENT: 80% dose of JOINTRUS®|DIETARY_SUPPLEMENT: 62.4% dose of JOINTRUS®|DIETARY_SUPPLEMENT: Starch 100%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Standardized Osteotomy Guides for Free Flap Reconstruction of Continuous Defects of the Jaws - a Simplified Method
Status: ENROLLING_BY_INVITATION
Conditions: Oral Surgical Procedures|Surgery, Oral|Mandibular Reconstruction
Interventions: PROCEDURE: Reconstruction
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Compare CNTO 328 (Anti-IL-6 Monoclonal Antibody) and VELCADE-Melphalan-Prednisone (VMP) With VMP Alone in Previously Untreated Multiple Myeloma Patients
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Siltuximab11 mg/kg|DRUG: Siltuximab 8.3 mg/kg or 11 mg/kg|DRUG: Velcade (bortezomib)|DRUG: Velcade (bortezomib)|DRUG: Melphalan|DRUG: Melphalan|DRUG: Prednisone|DRUG: Prednisone|DRUG: Velcade (bortezomib)|DRUG: Melphalan|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intermittent Oro-esophageal Tube on Rehabilitation Therapy Compliance in Stroke Patients
Status: NOT_YET_RECRUITING
Conditions: Stroke
Interventions: DEVICE: Intermittent Oro-esophageal Tube Feeding|DEVICE: Nasogastric Tube Feeding
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Oxaliplatin and Capecitabine in Treating Patients With Advanced Esophageal Cancer or Stomach Cancer
Status: COMPLETED
Conditions: Esophageal Cancer|Gastric Cancer
Interventions: DRUG: capecitabine|DRUG: oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Metabolic Surgery on Live Birth Rate of Offspring in Obesity Polycystic Ovarian Syndrome Patients
Status: UNKNOWN
Conditions: Polycystic Ovary Syndrome|Severe Obesity|Laparoscopic Sleeve Gastrectomy
Interventions: DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of CEND-1 With Chemotherapy as First-Line Therapy in Patients With Pancreatic Ductal Adenocarcinoma
Status: RECRUITING
Conditions: Pancreatic Ductal Adenocarcinoma (PDAC)
Interventions: DRUG: CEND-1|DRUG: Gemcitabine|DRUG: Nab paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparative Study of an Integrated Pharmaceutical Care Plan and a Routine Care in Bronchial Asthma
Status: COMPLETED
Conditions: Bronchial Asthma
Interventions: OTHER: Pharmacist- Intervention|OTHER: Routine Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Mucoadhesive Oral Wound Rinse in Preventing and Treating Stomatitis in Patients With ER- or PR-Positive Metastatic or Locally Recurrent Breast Cancer That Cannot be Removed by Surgery Receiving Everolimus
Status: COMPLETED
Conditions: Estrogen Receptor-positive Breast Cancer|HER2-negative Breast Cancer|Oral Complications|Progesterone Receptor-positive Breast Cancer|Recurrent Breast Cancer|Stage IIIB Breast Cancer|Stage IIIC Breast Cancer|Stage IV Breast Cancer
Interventions: DRUG: mucoadhesive oral wound rinse|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Exergaming in Advanced HF With Multiple Chronic Conditions Prior to LVAD Implantation or Heart Transplant
Status: COMPLETED
Conditions: Heart-Assist Devices|Heart Failure NYHA Class IV|Exercise Training
Interventions: BEHAVIORAL: PREHAB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Phase 3, Randomized, Double-blind, Placebo-controlled Study For Subjects With Locally-advanced Unresectable or Metastatic Synovial Sarcoma (V943-003, IMDZ-04-1702)
Status: TERMINATED
Conditions: Synovial Sarcoma|Cancer|Soft Tissue Sarcoma|Sarcoma|Metastatic Sarcoma
Interventions: BIOLOGICAL: LV305|BIOLOGICAL: G305|OTHER: LV305-matching placebo|OTHER: G305-matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: REmote CArdiac MOnitoring by the Corsano CardioWatch 287-2 Evaluation Study
Status: COMPLETED
Conditions: Atrial Fibrillation|Rhythm; Disorder|Palpitations|Hypertension|Hypotension
Interventions: DEVICE: Corsano CardioWatch 287-2
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: PAtient NOtifier Feature for Reduction of Anxiety
Status: COMPLETED
Conditions: Tachycardia, Ventricular
Interventions: DEVICE: ICD implant + Patient Notifier turned OFF|PROCEDURE: ICD Implant + Patient Notifier turned ON
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of Patients With Lower Extremity Acute Limb Ischemia to Remove Thrombus With the Indigo Aspiration System
Status: COMPLETED
Conditions: Lower Extremity Acute Limb Ischemia|LE ALI
Interventions: DEVICE: Indigo Aspiration System
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: suPAR is a Potential Biomarker of in Chronic Periodontitis Through the Impact of Post-radiotherapy on HNCs Patients
Status: COMPLETED
Conditions: Head and Neck Cancer|Chronic Periodontitis|Radiotherapy; Complications
Interventions: RADIATION: Head and Neck cancer post-radiotherapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: An Efficacy and Safety Study of Enzalutamide Plus Androgen Deprivation Therapy (ADT) Versus Placebo Plus ADT in Chinese Patients With Metastatic Hormone Sensitive Prostate Cancer (mHSPC)
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Hormone Sensitive Prostate Cancer
Interventions: DRUG: Enzalutamide|DRUG: Placebo|DRUG: Androgen deprivation therapy (ADT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: TMJ Adaptations by Orthodontic Treatment in Adolescent Males With Angle's Class II Division 2 Malocclusion: MRI Study
Status: COMPLETED
Conditions: Class II Division 2 Malocclusion
Interventions: OTHER: orthodontic treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cetuximab Plus Irinotecan in Colorectal Cancer Patients Who Progressed After Failure With Cetuximab Plus Irinotecan
Status: TERMINATED
Conditions: Colorectal Cancer
Interventions: DRUG: cetuximab with irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Preoperative and Postoperative Ankle Kinematics
Status: COMPLETED
Conditions: Ankle Osteoarthritis
Interventions: RADIATION: Roentgen Stereophotogrammetric Analysis (RSA)|DEVICE: Delos Postural Proprioceptive System (computerized oscillating platform)|DIAGNOSTIC_TEST: Modified Star Excursional Balance Tests|DEVICE: Inertial sensors Xsens MVN|OTHER: American Orthopaedic Foot and Ankle Score (AOFAs)|OTHER: Visual Analogue Scale (VAS)|OTHER: 12-Item Short Form Survey (SF-12)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Carboplatin, Abraxane, and Bevacizumab in Previously Untreated Patients With Advanced Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: carboplatin|DRUG: Nab-paclitaxel|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Issues of Moxifloxacin Plus Rifapentine
Status: TERMINATED
Conditions: Mycobacterium Tuberculosis
Interventions: DRUG: Moxifloxacin|DRUG: Rifapentine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Deplin® and Antidepressant Therapy for a Major Depressive Episode (MDE)- a Retrospective Analysis
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: L-methylfolate|DRUG: Selective serotonin reuptake inhibitor (SSRI)|DRUG: Serotonin and norepinephrine reuptake inhibitor (SNRI)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical Trial on the Articular Pain With a Cucumber Supplement in Patients Diagnosed With Arthrosis
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DIETARY_SUPPLEMENT: nutraceutical
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Conservative Methods for the Treatment of Lateral Epicondylitis: A Randomized, Prospective Study
Status: UNKNOWN
Conditions: Tennis Elbow|Lateral Epicondylitis
Interventions: DRUG: Placebo Injection|BEHAVIORAL: Physical Therapy|DRUG: Corticosteroid Injections|DRUG: Prolotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial for Measles - Rubella Combined Vaccine (MRVAC) Produced by POLYVAC (Phase III)
Status: COMPLETED
Conditions: Signs and Symptoms
Interventions: BIOLOGICAL: Trial arm (MRVAC)|BIOLOGICAL: Control arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: D-Cycloserine Augmentation of Cognitive Behavioral Therapy for Delusions
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder|Delusional Disorder
Interventions: DRUG: D-Cycloserine|OTHER: Placebo|BEHAVIORAL: Cognitive Behavioral Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Carfilzomib in Treating Patients With Chronic Graft-Versus-Host Disease
Status: COMPLETED
Conditions: Chronic Graft Versus Host Disease
Interventions: DRUG: Carfilzomib|OTHER: Laboratory Biomarker Analysis|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Study Between Protopic (Tacrolimus Ointment) and Elidel (Pimecrolimus Cream) in Treating Pediatric Patients With Atopic Dermatitis
Status: COMPLETED
Conditions: Dermatitis, Atopic
Interventions: DRUG: tacrolimus ointment|DRUG: pimecrolimus cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study the Effect of Acupuncture on Migraine Patient Without Aura Via Functional Magnetic Resonance Imaging.
Status: COMPLETED
Conditions: Migraine Without Aura
Interventions: BEHAVIORAL: Acupuncture stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Single Oral Dose Study to Evaluate Four Different Formulations of AZD9977 and the Effect of Food in Healthy Male Subjects
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: AZD9977 Oral suspension (reference)|DRUG: AZD9977 capsule|DRUG: AZD9977 ER capsule (fastvrate)|DRUG: AZD9977 ER capsule (Int. rate)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Long-term Safety and Efficacy of Tirabrutinib in Adults With Relapsed/Refractory B-cell Malignancies
Status: COMPLETED
Conditions: Relapsed/Refractory B-cell Malignancies
Interventions: DRUG: Tirabrutinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Personalized Behavioral Nutrition Intervention in Older AAs With T2D
Status: RECRUITING
Conditions: Type 2 Diabetes
Interventions: BEHAVIORAL: ADA-based nutrition education with digital self-monitoring|BEHAVIORAL: Personalized Behavioral Nutrition (PBN) intervention group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Association of CPP-ACPF Associated With LASER in the Treatment of Tooth Sensitivity After at Home Bleaching
Status: UNKNOWN
Conditions: Sensitivity, Tooth
Interventions: RADIATION: Laser of low frequncy|DRUG: CPP-ACPF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Efficacy and Safety of Tulisokibart (MK-7240) in Participants With Moderately to Severely Active Ulcerative Colitis (MK-7240-001)
Status: RECRUITING
Conditions: Ulcerative Colitis
Interventions: DRUG: IV Tulisokibart|DRUG: IV Placebo|DRUG: SC Tulisokibart|DRUG: SC Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Immunologic Basis for an Attenuated Immune Response to the Influenza Vaccine After Repeated Annual Vaccination
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: 2016-2017 Influenza Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Outcome of Omega 3 FA and Punctal Plugs on Ocular Surface Disease
Status: COMPLETED
Conditions: Ocular Surface Disease
Interventions: DRUG: Omega 3|DEVICE: punctal plug
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hormone Therapy Compared With Combination Chemotherapy in Treating Patients With Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: docetaxel|DRUG: estramustine phosphate sodium|DRUG: ketoconazole|DRUG: therapeutic hydrocortisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Study of Autologous Tumor Infiltrating Lymphocytes (LN-145) In Combo With Durvalumab in Non-Small Cell Lung Cancer
Status: WITHDRAWN
Conditions: Non Small Cell Lung Cancer
Interventions: BIOLOGICAL: LN-145|DRUG: Durvalumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of LoDoCo in Improving Exercise Capacity Among Patients With HFpEF and Inflammation
Status: RECRUITING
Conditions: Heart Failure|Inflammation
Interventions: DRUG: Low Dose Colchicine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Validation of New Devices Against Ambient Electromagnetic Radiation
Status: UNKNOWN
Conditions: Male Infertility
Interventions: DEVICE: new device against ambient electromagnetic radiation|DEVICE: sham device against ambient electromagnetic radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Hormone Ablation Therapy, Doxorubicin, and Zoledronate With or Without Strontium 89 in Treating Patients With Androgen-Dependent Prostate Cancer and Bone Metastases
Status: COMPLETED
Conditions: Metastatic Cancer|Prostate Cancer
Interventions: DRUG: Doxorubicin hydrochloride|DRUG: Goserelin acetate|DRUG: Leuprolide acetate|DRUG: Zoledronic acid|PROCEDURE: orchiectomy|RADIATION: strontium chloride Sr
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bicalutamide With or Without Metformin for Biochemical Recurrence in Overweight or Obese Prostate Cancer Patients
Status: COMPLETED
Conditions: Cancer of Prostate
Interventions: DRUG: Observation and Bicalutamide|DRUG: Metformin and Bicalutamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aflibercept +/- LV5FU2 in First Line of Non-resectalbe Metastatic Colorectal Cancers
Status: COMPLETED
Conditions: Colorectal Neoplasms
Interventions: DRUG: aflibercept|DRUG: LV5FU2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Impact of Exercise / Stress Stimuli on HMB Supplementation Efficacy
Status: RECRUITING
Conditions: Supplementation|Sport|Sports Nutrition|Sports Dietetics|Protein Kinases|Aerobic Capacity|Fat Free Mass
Interventions: DIETARY_SUPPLEMENT: HMB supplementation|DIETARY_SUPPLEMENT: Placebo treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Knee Flexion Angle for Graft Fixation During Single-Bundle Anterior Cruciate Ligament Reconstruction
Status: UNKNOWN
Conditions: Anterior Cruciate Ligament Injury
Interventions: PROCEDURE: knee flexion angle 1|PROCEDURE: knee flexion angle 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Study of the Safety, Tolerability and Pilot Efficacy of Oral Factor Xa Inhibitor Betrixaban Compared to Warfarin
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DRUG: betrixaban|DRUG: Warfarin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I Crossover Study of the Hemodynamic Interactions of Avanafil & Alcohol in Healthy Male Subjects.
Status: COMPLETED
Conditions: Erectile Dysfunction
Interventions: DRUG: avanafil|OTHER: alcohol|DRUG: avanafil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Single Dose Study to Investigate the Pharmacokinetics (PK) of Telitacicept Pre-filled Injection and Freeze-dried Powder Injection in Chinese Healthy Subjects
Status: RECRUITING
Conditions: Healthy
Interventions: DRUG: Telitacicept Pre-filled Injection 80mg|DRUG: Telitacicept Freeze-dried powder Injection 80mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pre-Implantation Genetic Screening in Women Under the Age of 36 Years With Single Embryo Transfer
Status: TERMINATED
Conditions: Live Birth Delivery Rate
Interventions: GENETIC: single embryo transfer without aneuploidy screening|GENETIC: single embryo transfer with aneuploidy screening
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Methylation Analysis of Circulating Tumor DNA in Gastric Cancer
Status: NOT_YET_RECRUITING
Conditions: Stomach Neoplasms|Circulating Tumor DNA
Interventions: DIAGNOSTIC_TEST: Circulating Tumor DNA Methylation Sequencing|DIAGNOSTIC_TEST: tissue DNA Methylation Sequencing
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Assess the Anti-fatigability Effect of CK-2127107 in Elderly Male and Female Subjects With Limitations in Mobility
Status: TERMINATED
Conditions: Mobility Limitation
Interventions: DRUG: reldesemtiv|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Feasabilty and Physiological Effects of a Ventilation Strategy Combining PEEP and Tidal Volume Titration According to Inspiratory and Expiratory Transpulmonary Pressures in ARDS Patients.
Status: UNKNOWN
Conditions: ARDS, Human
Interventions: OTHER: PEEP and Tidal Volume Titration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess Efficacy With Respect to Clinical Improvement in Disease Activity and Safety of Tocilizumab in Patients Wtih Active Rheumatoid Arthritis.
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Tocilizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Individualized and Combined Effects of Diabetes and Smoking on the Antiplatelet Activity of Ticagrelor in Acute Myocardial Infarction Patients Undergoing Primary PCI
Status: RECRUITING
Conditions: Individualized and Combined Effects of Smoking and Diabetes on the Antiplatelet Activity in Patients Undergoing Primary Percutaneous Coronary Intervention
Interventions: DRUG: Ticagrelor
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Bawei Shenqi Pill in the Treatment of Ankylosing Spondylitis
Status: UNKNOWN
Conditions: Ankylosing Spondylitis
Interventions: DRUG: Bawei Shenqi Pill|DRUG: Bawei Shenqi Pill placebo|DRUG: Meloxicam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy With or Without Atezolizumab in Treating Patients With Stage III Colon Cancer and Deficient DNA Mismatch Repair
Status: ACTIVE_NOT_RECRUITING
Conditions: Colon Adenocarcinoma|DNA Repair Disorder|Lynch Syndrome|Stage III Colon Cancer AJCC v8
Interventions: DRUG: Atezolizumab|PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|DRUG: Fluorouracil|DRUG: Leucovorin Calcium|PROCEDURE: Magnetic Resonance Imaging|DRUG: Oxaliplatin|OTHER: Quality-of-Life Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of a Sublingual Specific Immunotherapy With an Extract of a Six Grass Pollen Mixture
Status: COMPLETED
Conditions: Grass Pollen Allergy
Interventions: BIOLOGICAL: Grass pollen formulation|OTHER: Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Ankle Taping and Balance Exercises on Postural Stability
Status: COMPLETED
Conditions: Disturbance; Balance, Labyrinth|Proprioceptive Disorders
Interventions: OTHER: Balance exercise and ankle taping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Tocilizumab (RoActemra/Actemra) Versus Adalimumab in Patients With Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Tocilizumab|DRUG: Adalimumab|DRUG: Placebo to tocilizumab|DRUG: Placebo to adalimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Acute D2 Receptor Blockade Induced Neuronal Network Changes in Human Volunteers
Status: COMPLETED
Conditions: Imaging of the Brain and Antipsychotics|Neuronal Network Changes
Interventions: DRUG: Risperidone|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Phase II Study of Bevacizumab, Pemetrexed and Carboplatin as First-Line Therapy in Malignant Pleural Mesothelioma
Status: COMPLETED
Conditions: Mesothelioma
Interventions: DRUG: Bevacizumab, Pemetrexed, Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety, Tolerability and Pharmacokinetic Study of ABT-102 in Healthy Subjects
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: ABT-102|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Research of Spiral Exhalation Device Oxygen Therapy to Improve the Treatment Effect of Patients With Severe Pneumonia
Status: NOT_YET_RECRUITING
Conditions: Pneumonia
Interventions: DEVICE: high-flow oxygen therapy device for Severe pneumonia patients with artificial airway|DEVICE: AIRVOTM2 device for Severe pneumonia patients with artificial airway
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy and Safety of Olokizumab With Rheumatoid Arthritis With Previously Failed to Anti-tumor Necrosis Factor (Anti-TNF) Therapy
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: BIOLOGICAL: Placebo|BIOLOGICAL: Olokizumab 60 mg|BIOLOGICAL: Olokizumab 120 mg|BIOLOGICAL: Olokizumab 240 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Mindfulness-Based Compassionate Living Training Given to Caregivers of Inpatients in Palliative Clinic
Status: COMPLETED
Conditions: Informal Caregiver
Interventions: OTHER: Session 1: How We Evolved - Threat, Impulse, and Soothing Systems|OTHER: Session 2: Threat and Self-Compassion|OTHER: Session 3: Unraveling the Knots of Desire and Patterns|OTHER: Session 4: Internalizing compassion|OTHER: Session 5: Me and others - Expanding the circle|OTHER: Session 6: Growing happiness|OTHER: Session 7: Weaving Wisdom and Compassion into Daily Life|OTHER: Session 8: Living with the Heart
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Long Term Clinical Efficacy of Sodium-glucose Cotransporter-2 (SGLT-2) Inhibitor in Cystinurics
Status: NOT_YET_RECRUITING
Conditions: Cystinuria
Interventions: DRUG: Dapagliflozin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral Sucrose Versus Glucose for Procedural Pain in Premature Neonates
Status: COMPLETED
Conditions: Neonatal Procedural Pain
Interventions: OTHER: 24% oral sucrose|OTHER: 30% oral glucose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Trendelenburg Maneuver Predicts Fluid Responsiveness in Patients With Extracorporeal Membrane Oxygenation (TEMPLE)
Status: UNKNOWN
Conditions: Extracorporeal Membrane Oxygenation
Interventions: DIAGNOSTIC_TEST: Trendelenburg Maneuver
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adjuvant HIPEC to Prevent Colorectal Peritoneal Metastases in High-risk Patients
Status: COMPLETED
Conditions: Colorectal Neoplasm|Metastasis
Interventions: DRUG: adjuvant HIPEC|PROCEDURE: surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Tradipitant on Satiation, Gastric Volume, Gastric Accommodation, and Gastric Emptying in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: Tradipitant|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Orthognathic Surgeries and Pharyngeal Airway Space
Status: COMPLETED
Conditions: Mandibular Prognathism
Interventions: PROCEDURE: mandibular setback and maxillary advancement|PROCEDURE: mandibular setback
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating Mitoxantrone in Multiple Sclerosis
Status: TERMINATED
Conditions: Secondary Progressive Multiple Sclerosis
Interventions: DRUG: Mitoxantrone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Incorporating Positive Affect Promoting Activities Into Cognitive Behavioral Therapies
Status: RECRUITING
Conditions: Depression|Borderline Personality Disorder|Emotion Regulation
Interventions: BEHAVIORAL: Psychotherapy, Positive Affect Promoting Activities|BEHAVIORAL: Psychotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Music Use for Sedation In Critically Ill Children
Status: COMPLETED
Conditions: Music Therapy|Critical Care|Analgesia|Ventilators, Mechanical
Interventions: OTHER: Music
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Extension Study of Idursulfase-IT Along With Elaprase in Children and Adults With Hunter Syndrome and Cognitive Impairment
Status: RECRUITING
Conditions: Hunter Syndrome
Interventions: DRUG: Idursulfase-IT|DRUG: Elaprase
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Guselkumab in the Treatment of Participants With Active Psoriatic Arthritis (PsA)
Status: COMPLETED
Conditions: Psoriatic Arthritis
Interventions: DRUG: Guselkumab|DRUG: Ustekinumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: iFR Guided Multi-vessel Revascularization During Percutaneous Coronary Intervention for Acute Myocardial Infarction
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Myocardial Infarction|Multi Vessel Coronary Artery Disease
Interventions: DIAGNOSTIC_TEST: iFR|DIAGNOSTIC_TEST: CMR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Phase II Study of Lenalidomide for the Treatment of Relapsed or Refractory Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Hodgkin Disease
Interventions: DRUG: Lenalidomide (Revlimid®)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fluoxetine Opens Window to Improve Motor Recovery After Stroke
Status: COMPLETED
Conditions: Stroke|Cerebrovascular Accident|Cerebral Infarction|Brain Infarction|Brain Ischemia|Cerebrovascular Disorders|Brain Diseases|Central Nervous System Diseases|Nervous System Diseases|Vascular Diseases
Interventions: DRUG: Fluoxetine Hydrochloride|OTHER: Placebo|BEHAVIORAL: Exercise Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Amyloid Prediction in Early Stage Alzheimer's Disease Through Speech Phenotyping - PAST Extension
Status: UNKNOWN
Conditions: Alzheimer Disease|Alzheimer's Disease (Incl Subtypes)|Preclinical Alzheimer's Disease|Prodromal Alzheimer's Disease|Mild Cognitive Impairment|Normal Cognition
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Accuracy of Variables for Impacted Mandibular Third Molar Surgery
Status: UNKNOWN
Conditions: Impacted Third Molar Tooth
Interventions: DIAGNOSTIC_TEST: Wharfe and Pederson difficulty index|DIAGNOSTIC_TEST: Winters difficulty index
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Cisplatinum and Everolimus in Patients With Metastatic or Unresectable NEC of Extrapulmonary Origin
Status: UNKNOWN
Conditions: Neuroendocrine Carcinomas
Interventions: DRUG: cisplatinum and everolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Synapse Transcutaneous Electronic Nerve Stimulation (TENS) During Dental Procedures Among Children
Status: WITHDRAWN
Conditions: Dental Fear|Anesthesia, Local|Pediatric Dentistry
Interventions: DEVICE: Synapse TENS device|DRUG: Topical anesthetic gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Weight Reduction With the Low-Insulin-Method
Status: COMPLETED
Conditions: Overweight and Obesity
Interventions: BEHAVIORAL: Telemedical coaching|BEHAVIORAL: Low-Insulin-Method
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: CAR20(NAP)-T Therapy for B Cell Lymphoma (CARMA-01 Study)
Status: RECRUITING
Conditions: B-cell Lymphoma
Interventions: BIOLOGICAL: CAR20(NAP)-T|DRUG: Cyclophosphamide|DRUG: Fludarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: IMMULAB - Immunotherapy With Pembrolizumab in Combination With Local Ablation in Hepatocellular Carcinoma (HCC)
Status: COMPLETED
Conditions: Hepatocellular Carcinoma (HCC)
Interventions: DRUG: Pembrolizumab|PROCEDURE: Radio Frequency Ablation (RFA)|PROCEDURE: Microwave Ablation (MWA)|RADIATION: Brachytherapy|DRUG: Transarterial Chemoembolisation (TACE)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Efficacy and Safety of Abatacept in Adults With Active Primary Sjögrens Syndrome
Status: COMPLETED
Conditions: Sjogrens Disease
Interventions: BIOLOGICAL: Abatacept|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial to Assess the Long Term Safety and Tolerability of MK-0653C in Japanese Participants With Hypercholesterolemia (MK-0653C-384)
Status: COMPLETED
Conditions: Hypercholesterolemia|Heterozygous Familial Hypercholesterolemia
Interventions: DRUG: EZ 10 mg/Atorva 20 mg FDC|DRUG: EZ 10 mg/Atorva 10 mg FDC
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long-term Adverse Effects After Bariatric Surgery on Bone Density
Status: COMPLETED
Conditions: Morbid Obesity
Interventions: DIAGNOSTIC_TEST: DEXA (= Dual-energy x-ray absorptiometry)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC