pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Efficacy and Safety of Heme-Iron Polypeptide on Improvement of Anemia
Status: COMPLETED
Conditions: Anemia
Interventions: DIETARY_SUPPLEMENT: Heme-Iron Polypeptide|DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: Heme-Iron|DIETARY_SUPPLEMENT: Organic Iron
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Synergistic Influence of Rivaroxaban on Inflammation and Coagulation Biomarkers in Patients With CAD and PAD on Aspirin Therapy
Status: UNKNOWN
Conditions: Coronary Artery Disease|Peripheral Artery Disease
Interventions: DRUG: Rivaroxaban 2.5 Mg Oral Tablet|DRUG: Aspirin 81 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study of Sequential Perfusion of Liver Grafts to Prevent Nonanastomotic Biliary Strictures After Liver Transplantation
Status: COMPLETED
Conditions: Liver Transplantation|Transplant Recipient
Interventions: PROCEDURE: sequential perfusion with ipv Ross solution and UW solution|PROCEDURE: sole perfusion with UW solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Optical Detection of Peripheral Nerve Bundles During Surgery
Status: COMPLETED
Conditions: Malignant Lymphoma of Lymph Nodes of Inguinal Region|Malignant Lymphoma of Lymph Nodes of Axillary|Malignant Lymphoma of Lymph Nodes of the Cervix|Carcinoma of Parotid Gland|Colon Rectal Cancer Tubulovillous Adenocarcinoma|Tumor of Soft Tissue of Head, Face and Neck
Interventions: PROCEDURE: Surgical resection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Local Infiltration With Ropivacaine Improves Postoperative Pain Control in Patients
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: Ropivacaine|DRUG: 0.9% saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Epicardial Mitral Touch System for Mitral Insufficiency
Status: NOT_YET_RECRUITING
Conditions: Ischemic Mitral Regurgitation|Functional Mitral Regurgitation
Interventions: DEVICE: Implant an epicardial device to reshape the mitral valve annulus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Treating Cognitive Deficits in Spinal Cord Injury
Status: COMPLETED
Conditions: Spinal Cord Injury|Blood Pressure|Cerebral Blood Flow|Cognitive Function
Interventions: OTHER: SPT|OTHER: SPT Control|OTHER: mSMT|OTHER: mSMT Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transcutaneous Afferent Patterned Stimulation (TAPS) for Reduction of Parkinson's Disease (PD) Related Action Tremor
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: DEVICE: Cala Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gene Transfer for Recessive Dystrophic Epidermolysis Bullosa
Status: COMPLETED
Conditions: Epidermolysis Bullosa Dystrophica|Epidermolysis Bullosa
Interventions: BIOLOGICAL: LZRSE-Col7A1 Engineered Autologous Epidermal Sheets
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Probiotics on Oral Wound Healing - Pilot Study
Status: COMPLETED
Conditions: Wound
Interventions: DIETARY_SUPPLEMENT: L. reuteri DSM 17938/ATCC PTA|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Seattle Spatial Transcriptomic Research in Inflammatory Bowel Disease Evaluation (STRIDE)
Status: NOT_YET_RECRUITING
Conditions: Inflammatory Bowel Diseases|Crohn Disease|Ulcerative Colitis|Indeterminate Colitis|Functional Abdominal Pain Syndrome|Functional Bowel Disorder|Esophageal Diseases|Gastroduodenal Disorder|Bowel Dysfunction|Gallbladder Diseases|Sphincter of Oddi Dysfunction|Anorectal Disorder
Interventions: DIAGNOSTIC_TEST: Esophagogastroduodenoscopy (EGD) with biopsy|DIAGNOSTIC_TEST: Colonoscopy w/ biopsy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study to Determine the Safety and the Efficacy of Fasinumab Compared to Placebo and Nonsteroidal Anti-inflammatory Drugs (NSAIDs) for Treatment of Adults With Pain From Osteoarthritis of the Knee or Hip
Status: COMPLETED
Conditions: Osteoarthritis, Knee|Osteoarthritis, Hip
Interventions: DRUG: Fasinumab|OTHER: Diclofenac|OTHER: Celecoxib|DRUG: Matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Osimertinib Combined With Bevacizumab in the Treatment Epidermal Growth Factor Receptor (EGFR) Exon 20 Insertions Metastatic Non-Small Cell Lung Cancer
Status: RECRUITING
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: Osimertinib Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Double Blind Control Trial on Effects of Ranolazine on New Onset Atrial Fibrillation
Status: TERMINATED
Conditions: Atrial Fibrillation New Onset|Hemorrhage|Prolonged QTc Interval|Ventricular Tachycardia|Medical Care; Complications, Late Effect of Complications
Interventions: DRUG: Ranolazine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Anesthetics on CD39 and CD73 After Open-heart Surgery
Status: COMPLETED
Conditions: Valvular Heart Disease|Aortic Disease
Interventions: DRUG: Propofol|DRUG: Sevoflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: HELIOS-A: A Study of Vutrisiran (ALN-TTRSC02) in Patients With Hereditary Transthyretin Amyloidosis (hATTR Amyloidosis)
Status: ACTIVE_NOT_RECRUITING
Conditions: Amyloidosis, Hereditary|Transthyretin Amyloidosis
Interventions: DRUG: Patisiran|DRUG: Vutrisiran
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mode Of Ventilation During Critical IllnEss Pilot Trial
Status: COMPLETED
Conditions: Respiratory Failure
Interventions: OTHER: Volume Control mode|OTHER: Pressure Control mode|OTHER: Adaptive Pressure Control mode
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Communities of Healing Mentorship/Support Group Program: Assessment of Preliminary Efficacy
Status: COMPLETED
Conditions: Eating Disorder|Anorexia Nervosa|Bulimia Nervosa|Binge-Eating Disorder
Interventions: BEHAVIORAL: Peer mentorship|BEHAVIORAL: Social support mentorship|BEHAVIORAL: Recovery Record use with mentor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: "Sandwich" Chemotherapy With Radiotherapy in Newly Diagnosed, Stage IE to IIE, ENKTL
Status: TERMINATED
Conditions: Treatment Refusal
Interventions: DRUG: P-CHOP|RADIATION: Radiotherapy|DRUG: P-CHOP
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of A-PRF After Removal of Wisdom Teeth
Status: COMPLETED
Conditions: Wound Heal
Interventions: OTHER: autologous blood clot made from the patient own clot without any additive
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of ZD1839 Combined With Irinotecan and Vincristine in Pediatric Patients With Refractory Solid Tumors
Status: COMPLETED
Conditions: Solid Tumors
Interventions: DRUG: Irinotecan, ZD1839, Vincristine, Cefixime, Cefpodoxime.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Q10 Preloading Before Cardiac Surgery for Kidney Failure Reduction
Status: UNKNOWN
Conditions: Acute Kidney Injury|Acute Kidney Failure
Interventions: DIETARY_SUPPLEMENT: Coenzyme Q10
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Developmental Screening and Nutritional Intervention of Severe Acute Malnourished Children in Southern Punjab, Pakistan
Status: COMPLETED
Conditions: Malnutrition in Children
Interventions: DIETARY_SUPPLEMENT: Vitamin D|DIETARY_SUPPLEMENT: Ready to Use Therapeutic Food (RUTF)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Assess the Efficacy of HH-120 Nasal Spray for Prevention of SARS-CoV-2 Infection in Adult Close Contacts of Individuals Infected With SARS-CoV-2
Status: COMPLETED
Conditions: SARS-CoV-2 Infection
Interventions: DRUG: HH-120 nasal spray 1|DRUG: HH-120 nasal spray 2|DRUG: Placebo Comparator 1|DRUG: Placebo Comparator 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Phase 1b Study of EZH1/2 Inhibitor Valemetostat in Combination With Trastuzumab Deruxtecan in Subjects With HER2 Low/Ultra-low/Null Metastatic Breast Cancer
Status: RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Trastuzumab deruxtecan|DRUG: Valemetostat
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of the Mometasone Nasal Gel in the Treatment of Persistent Allergic Rhinitis
Status: WITHDRAWN
Conditions: Allergic Rhinitis
Interventions: DRUG: EMS Mometasone gel|DRUG: Mometasone spray nasal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Outcome of Two Different Suture Methods for Achilles Tendon Rupture
Status: UNKNOWN
Conditions: Achilles Tendon Rupture
Interventions: PROCEDURE: sewed indirectly|PROCEDURE: sewed directly
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Injections of Glutamic Acid Decarboxylase (GAD) for LADA Type of Diabetes
Status: COMPLETED
Conditions: Latent Autoimmune Diabetes in Adults
Interventions: DRUG: recombinant human glutamic acid dehydrogenase (rhGAD65), formulated in aluminium hydrogel|DRUG: Vitamin D
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 18 Fluoro-deoxy-glucose Positrons Emission Tomography Combined With Computed Tomography (18-FDG TEP-CT ) in the Diagnosis of the Degeneration of Intraductal Papillary Mucinous Tumor of the Pancreas
Status: COMPLETED
Conditions: Tumor
Interventions: OTHER: 18 fluoro-deoxy-glucose positrons emission tomography combined with computed tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Metformin for Antipsychotic-induced Weight Gain in Adults With Intellectual Disability
Status: RECRUITING
Conditions: Intellectual Disability|Developmental Disability|Obesity
Interventions: DRUG: Metformin|DRUG: Placebo|BEHAVIORAL: Lifestyle Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Eltrombopag Plus Diacerein vs Eltrombopag in Adult ITP
Status: COMPLETED
Conditions: Thrombocytopenia
Interventions: DRUG: Eltrombopag plus diacerein|DRUG: Eltrombopag
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pharmacokinetic (PK) Study of Natalizumab (Tysabri) at Steady State
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DRUG: Natalizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: 18F-DCFBC PET/CT in Prostate Cancer
Status: COMPLETED
Conditions: Prostatic Neoplasms|Prostate Cancer
Interventions: DRUG: 18F DCFBC|DRUG: Sodium (Na)18F positron emission tomography (PET)/computed tomography (CT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Meta-analyses of the Effect of Sucrose Versus High Fructose Corn Syrup on Cardiometabolic Risk
Status: UNKNOWN
Conditions: Obesity|Dyslipidemia|Prediabetes|Dysglycemia|Gout|Hypertension|Non-Alcoholic Fatty Liver Disease|Cardiovascular Disease
Interventions: OTHER: High Fructose Corn Syrup|OTHER: Sucrose
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Ropidoxuridine as a Radiosensitizer in Newly Diagnosed IDH-Wildtype Glioblastoma With Unmethylated MGMT Promoter
Status: NOT_YET_RECRUITING
Conditions: Glioblastoma, IDH-wildtype
Interventions: DRUG: Ropidoxuridine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial of Pentoxifylline for the Treatment of Recurrent Aphthous Stomatitis
Status: COMPLETED
Conditions: Recurrent Aphthous Stomatitis
Interventions: DRUG: Pentoxifylline (also known as oxpentifylline)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Acquired Immunodeficiency in ANCA Associated Vasculitis
Status: UNKNOWN
Conditions: Systemic Vasculitis
Interventions: BIOLOGICAL: Pneumococcal Polysaccharide Conjugate vaccination and Pneumococcal Polysaccharide Vaccination
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Mycophenolate Mofetil Treatment With Neuromyelitis Optica Spectrum Disorders in Chinese Patients
Status: UNKNOWN
Conditions: Neuromyelitis Optica Spectrum Disorders|Mycophenolate Mofetil|Efficacy and Safety
Interventions: DRUG: Mycophenolate mofetil|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Feasibility and Accuracy of Exhaled CO2 to Measure Cardiac Output in Ventilated Patients Without Tracheal Intubation
Status: WITHDRAWN
Conditions: Cardiac Physiology|Cardiac Output
Interventions: DEVICE: NICO device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: An Observational Study On TheAccuracy Of Whole-Body Magnetic Resonance Imaging (Wb-Mri) ScreeningTo Predict Clinically Significant Diagnoses In General Population Subjects Interested In Proactive And Advanced General Preventive Healthcare.
Status: RECRUITING
Conditions: Cancer|Metabolic Disease|Aneurysm|Neurologic Disorder
Interventions: DIAGNOSTIC_TEST: MRI Scan
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: PASS OCT® Post-market Clinical Follow-up
Status: COMPLETED
Conditions: Intervertebral Disc Disease|Spondylolisthesis|Spinal Stenosis|Spinal Neoplasms|Spinal Fractures
Interventions: DEVICE: PASS OCT® Spinal System
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Guo's Aortic Arch Reconstruction: A Multicenter, Prospective Study of the Novel WeFlow-Tribranch System (GENIUS Study)
Status: RECRUITING
Conditions: Aortic Arch Aneurysm
Interventions: DEVICE: WeFlow-Tribranch embedded aortic Triple-branch arch Stent Graft system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Education on BDNF on Pain Levels
Status: RECRUITING
Conditions: Chronic Pain|Musculoskeletal Pain
Interventions: BEHAVIORAL: Pain Neuroscience Education|BEHAVIORAL: Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Tripterygium Wilfordii in Patients With Rheumatoid Arthritis
Status: COMPLETED
Conditions: Arthritis, Rheumatoid
Interventions: DRUG: Tripterygium wilfordii Hook F|DRUG: Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Ultrasound Guided Transversus Abdominis Plane Nerve Block Techniques
Status: COMPLETED
Conditions: Crohn's Disease|Inflammatory Bowel Disease|Postoperative Pain
Interventions: OTHER: Placebo|DRUG: US TAP Bupivacaine/Epinephrine|DRUG: Lap TAP Bupivacaine/Epinephrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing Exparel & Ropivacaine for Pain Relief in Total Knee Arthroplasty
Status: UNKNOWN
Conditions: Knee Osteoarthritis
Interventions: DRUG: Exparel|DRUG: Ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Velcade, Melphalan, Prednisone And Thalidomide Versus Velcade, Melphalan, Prednisone in Multiple Myeloma Patients
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Bortezomib, Melphalan, Prednisone, Thalidomide|DRUG: Bortezomib, Melphalan, Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: External Oblique Intercostal Plane Block for Liver Transplantation Donors
Status: COMPLETED
Conditions: Liver Transplantation|Donor|Postoperative Pain
Interventions: OTHER: Subcostal transversus abdominis plane block|OTHER: External oblique intercostal plane block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Antithrombin III Concentrate After Liver Transplantation
Status: COMPLETED
Conditions: Liver Transplant; Complications
Interventions: DRUG: Antithrombin III, continuous infusion|DRUG: Antithrombin III, Intermittent infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Efficacy of Ergonomic Intervention in Preventing Musculoskeletal Disorders Among Women After Giving Birth
Status: UNKNOWN
Conditions: Musculoskeletal Disorders|Musculoskeletal Pain|Post Partum
Interventions: OTHER: Ergonomic workshop|OTHER: Brochure|OTHER: Videos
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Cessation of Somatostatin Analogues After PRRT in Mid, Hind-Gut and Pancreatic Neuroendocrine Tumours
Status: NOT_YET_RECRUITING
Conditions: Neuroendocrine Tumors
Interventions: DRUG: Cessation of somatostatin analogues|DRUG: Continuation of somatostatin analogues
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Cobimetinib in Participants With Solid Tumors
Status: COMPLETED
Conditions: Solid Tumor
Interventions: DRUG: cobimetinib|DRUG: dextromethorphan|DRUG: midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Protective Effect of Electroacupuncture on Lung in Patients Undergoing General Anesthesia
Status: UNKNOWN
Conditions: Electroacupuncture|Lung Injury, Ventilator Induced
Interventions: OTHER: electroacupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of Subcutaneously (SC) Administered Tocilizumab (TCZ) in Participants With Polyarticular-Course Juvenile Idiopathic Arthritis (pJIA)
Status: COMPLETED
Conditions: Juvenile Idiopathic Arthritis
Interventions: DRUG: Tocilizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Impact of Omega-3 Fat Emulsion on Clinical Outcome of Post-Operative Cancer Patients
Status: COMPLETED
Conditions: Carcinoma Surgery|Parenteral Nutrition|Post-Operative Hospital Stay
Interventions: DRUG: Omega-3 fish oil emulsion (Omegaven )|DRUG: long-chain triglyceride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Open-label Study to Assess Reduction of Background Asthma Medication While Sustaining Asthma Control and Clinical Remission With Tezepelumab in Patients 12-80yrs With Severe Asthma.
Status: NOT_YET_RECRUITING
Conditions: Severe Asthma
Interventions: COMBINATION_PRODUCT: Tezepelumab|COMBINATION_PRODUCT: Budesonide/formoterol|COMBINATION_PRODUCT: Albuterol/budesonide (AIRSUPRA®)|COMBINATION_PRODUCT: Mannitol|COMBINATION_PRODUCT: Salbutamol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ENGOT-cx1/BGOG-cx1: 3 Weekly Carboplatin/Paclitaxel With or Without Nintedanib in Cervix Cancer
Status: COMPLETED
Conditions: Uterine Cervical Neoplasms
Interventions: DRUG: Nintedanib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intranasal Oxytocin Administration and the Neural Correlates of Social and Non-Social Visual Perception
Status: COMPLETED
Conditions: Social Perception
Interventions: DRUG: Oxytocin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of LY3502970 in Participants With Obesity or Overweight With Weight-related Comorbidities
Status: COMPLETED
Conditions: Obesity|Overweight and Obesity
Interventions: DRUG: LY3502970|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Department of Defense PTSD Adaptive Platform Trial - Intervention B - Vilazodone
Status: NOT_YET_RECRUITING
Conditions: Post Traumatic Stress Disorder
Interventions: DRUG: Intervention B Vilazodone Hydrochloride (HCl)|DRUG: Intervention B Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Protein Ingestion and Resistance Exercise in Elderly
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Whey protein|DIETARY_SUPPLEMENT: Milk protein|DIETARY_SUPPLEMENT: Carbohydrates
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Veliparib, Capecitabine, and Temozolomide in Patients With Advanced, Metastatic, and Recurrent Neuroendocrine Tumor
Status: WITHDRAWN
Conditions: Functional Pancreatic Neuroendocrine Tumor|Malignant Somatostatinoma|Merkel Cell Carcinoma|Metastatic Adrenal Gland Pheochromocytoma|Metastatic Carcinoid Tumor|Multiple Endocrine Neoplasia Type 1|Multiple Endocrine Neoplasia Type 2A|Multiple Endocrine Neoplasia Type 2B|Neuroendocrine Neoplasm|Non-Functional Pancreatic Neuroendocrine Tumor|Pancreatic Glucagonoma|Pancreatic Insulinoma|Recurrent Adrenal Cortex Carcinoma|Recurrent Adrenal Gland Pheochromocytoma|Recurrent Merkel Cell Carcinoma|Somatostatin-Producing Neuroendocrine Tumor|Stage III Adrenal Cortex Carcinoma|Stage III Thyroid Gland Medullary Carcinoma|Stage IIIA Merkel Cell Carcinoma|Stage IIIB Merkel Cell Carcinoma|Stage IV Adrenal Cortex Carcinoma|Stage IV Merkel Cell Carcinoma|Stage IVA Thyroid Gland Medullary Carcinoma|Stage IVB Thyroid Gland Medullary Carcinoma|Stage IVC Thyroid Gland Medullary Carcinoma|Thymic Carcinoid Tumor|VIP-Producing Neuroendocrine Tumor|Well Differentiated Adrenal Cortex Carcinoma|Zollinger Ellison Syndrome
Interventions: DRUG: Capecitabine|DRUG: Temozolomide|DRUG: Veliparib|OTHER: Pharmacological Study|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of OT-82 in Participants With Relapsed or Refractory Lymphoma
Status: UNKNOWN
Conditions: Lymphoma|Lymphoma, Non-Hodgkin|Lymphoma, B-Cell|Lymphoma, T-Cell|Lymphoma, Follicular|Lymphoma, Peripheral T-Cell|Lymphoma, Hodgkin
Interventions: DRUG: OT-82 Dose Escalation|DRUG: OT-82 Dose Expansion
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effectiveness of the Nebulization Bronchodilators Under High Nasal Flow Humidified
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DEVICE: Airvo2 with Aerogen Solo|DEVICE: Mask|DEVICE: arm control Airvo2 without nebulization of salbutamol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Oral NOMAC-E2 in Indian Women (P07057/MK-8175A-017)
Status: WITHDRAWN
Conditions: Contraception
Interventions: DRUG: Nomegestrol acetate (NOMAC)|DRUG: Estradiol (E2)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lactobacillus Reuteri for Prevention of Necrotizing Enterocolitis in Very Low-birth Weight Infants
Status: COMPLETED
Conditions: Necrotizing Enterocolitis|Very Low Birth Weight Infants
Interventions: DRUG: Lactobacillus reuteri|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Trial of Ferumoxytol for the Episodic Treatment of Iron Deficiency Anemia in Pediatric Participants With Chronic Kidney Disease
Status: TERMINATED
Conditions: Iron Deficiency Anemia
Interventions: DRUG: Ferumoxytol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Trauma-Related Anger in OEF/OIF/OND Veterans
Status: COMPLETED
Conditions: Anger Problems
Interventions: BEHAVIORAL: Cognitive Behavioral Intervention|BEHAVIORAL: Supportive Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigating the Effects of Intensity of Transcranial Direct Current Stimulation on Subjective Appetite
Status: UNKNOWN
Conditions: Healthy
Interventions: DEVICE: 1 mA tDCS|DEVICE: 1.5 mA tDCS|DEVICE: Sham tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Treatment of Dry Eye Using 0.03% Tacrolimus Eye Drops
Status: COMPLETED
Conditions: Sjogren Syndrome|Dry Eye Syndrome
Interventions: DRUG: Tacrolimus|DRUG: Olive Oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Geriatric Assessment and Outcome in Patients Undergoing Transcatheter Aortic Valve Replacement
Status: COMPLETED
Conditions: Influence of Geriatric Functional State on the Outcome After TAVI|Possible Change in Geriatric Assessment After TAVI
Interventions: OTHER: pre- and postinterventional geriatric assessment in patients undergoing TAVI
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pembrolizumab in Treating Patients With Relapsed or Refractory Stage IB-IVB Mycosis Fungoides or Sezary Syndrome
Status: COMPLETED
Conditions: Recurrent Mycosis Fungoides and Sezary Syndrome|Refractory Mycosis Fungoides and Sezary Syndrome|Stage IB Mycosis Fungoides and Sezary Syndrome AJCC v7|Stage IIA Mycosis Fungoides and Sezary Syndrome AJCC v7|Stage IIB Mycosis Fungoides and Sezary Syndrome AJCC v7|Stage IIIA Mycosis Fungoides and Sezary Syndrome AJCC v7|Stage IIIB Mycosis Fungoides and Sezary Syndrome AJCC v7|Stage IVA Mycosis Fungoides and Sezary Syndrome AJCC v7|Stage IVB Mycosis Fungoides and Sezary Syndrome AJCC v7
Interventions: OTHER: Laboratory Biomarker Analysis|BIOLOGICAL: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Proof of Concept Pilot Study of the Addition of Venetoclax to Standard Remission Induction Chemotherapy Fludarabine or Cladrabine, Cytarabine, and Granulocyte Colony Stimulating Factor (G-CSF) (FLAG or CLAG) for Frontline Therapy of Secondary Acute Myeloid Leukemia
Status: RECRUITING
Conditions: Secondary Acute Myeloid Leukemia
Interventions: DRUG: Venetoclax|DRUG: FLAG or CLAG Protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Maximizing Extubation Outcomes Through Educational and Organizational Research (METEOR) Trial
Status: ENROLLING_BY_INVITATION
Conditions: Acute Respiratory Failure|Airway Extubation
Interventions: BEHAVIORAL: Traditional online education|BEHAVIORAL: Interprofessional education|BEHAVIORAL: Clinical protocol|OTHER: Risk-stratified preventive post-extubation noninvasive ventilation (NIV) or high-flow nasal cannula oxygen (HFNC)|OTHER: Preventive post-extubation high-flow nasal cannula oxygen (HFNC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Infusion of Depleted T Cells Following Unrelated Donor Stem Cell Transplant (ICAT)
Status: COMPLETED
Conditions: Haematological Malignancies
Interventions: BIOLOGICAL: CD25/71 allodepleted donor T-cells
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Impact of Bryophyllum on Preterm Delivery
Status: COMPLETED
Conditions: Preterm Delivery|Preterm Contractions|Cervical Shortening
Interventions: DRUG: Bryophyllum|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Dry Needling and Patients Treatment Expectations
Status: RECRUITING
Conditions: Neck Pain; Dry Needling; Motivation
Interventions: OTHER: Positive expectation AND dry needling in the upper trapezius fibers, at the most painful point|OTHER: Neutral expectation AND dry needling in the upper trapezius fibers, at the most painful point|OTHER: Negative expectation AND dry needling in the upper trapezius fibers, at the most painful point
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The MHERO Study (Michigan's Hypertension, Diabetes, and Obesity Education Research Online)
Status: COMPLETED
Conditions: Type2 Diabetes Mellitus|Hypertension|PreDiabetes|Overweight and Obesity
Interventions: BEHAVIORAL: DASH diet|BEHAVIORAL: Very low carbohydrate, ketogenic diet|BEHAVIORAL: Extras
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SRT in Combination With Pembrolizumab in Patients With Recurrent Prostate Cancer After Radical Prostatectomy
Status: RECRUITING
Conditions: Urologic Cancer|Biochemical Recurrence of Malignant Neoplasm of Prostate
Interventions: DRUG: Pembrolizumab Injection [Keytruda]|RADIATION: Salvage Radiation Therapy (SRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment, Parallel Assignment, Double Blind (Subject, Outcomes Assessor), Efficacy Study
Status: UNKNOWN
Conditions: Overactive Bladder
Interventions: DEVICE: Electroacupuncture|DEVICE: Sham Electroacupuncture|DRUG: Solifenacin Succinate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sativex Versus Placebo When Added to Existing Treatment for Central Neuropathic Pain in MS
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DRUG: Sativex|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Low-Dose Selinexor and Choline Salicylate for Non-Hodgkin or Hodgkin Lymphoma, Histiocytic/Dendritic Cell Neoplasm, or Relapsed or Refractory Multiple Myeloma
Status: RECRUITING
Conditions: Recurrent Histiocytic and Dendritic Cell Neoplasm|Recurrent Hodgkin Lymphoma|Recurrent Non-Hodgkin Lymphoma|Recurrent Plasma Cell Myeloma|Refractory Histiocytic and Dendritic Cell Neoplasm|Refractory Hodgkin Lymphoma|Refractory Non-Hodgkin Lymphoma|Refractory Plasma Cell Myeloma
Interventions: DRUG: Choline Salicylate|DRUG: Selinexor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cervical Paraspinal Muscle Twitching and Cervical Facet Radiofrequency Ablation Outcomes
Status: RECRUITING
Conditions: Cervical Facet Joint Pain|Chronic Pain|Neck Pain
Interventions: PROCEDURE: Cervical Radiofrequency Ablation (RFA)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Spinal Stenosis Pedometer and Nutrition e-Health Lifestyle Intervention (SSPANLI) Trial
Status: UNKNOWN
Conditions: Lumbar Spinal Stenosis|Obesity
Interventions: BEHAVIORAL: Lifestyle intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety of Hib-MenCY-TT Vaccine Versus Licensed Hib Conjugate Vaccine, Given at 2, 4, 6 and 12 to 15 Months of Age
Status: COMPLETED
Conditions: Haemophilus Influenzae Type b|Neisseria Meningitidis
Interventions: BIOLOGICAL: GSK Biologicals' Haemophilus influenzae type b and Neisseria meningitidis serogroups C and Y-tetanus toxoid conjugate vaccine combined 792014|BIOLOGICAL: ActHIB|BIOLOGICAL: Pediarix/Infanrix Penta
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: At-Home Exercise Study for Veterans With Healed Diabetic Foot Ulcers
Status: NOT_YET_RECRUITING
Conditions: Diabetic Foot Ulcer
Interventions: BEHAVIORAL: 12-week home based exercise|BEHAVIORAL: 12-week standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Study to Investigate the Safety, Tolerability and Pharmacokinetics of AZD1386
Status: COMPLETED
Conditions: Chronic Pain
Interventions: DRUG: AZD1386|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Vitamin C Enriched Hydrolyzed Collagen, PrimaColl™, Whey Protein, or Placebo on Collagen Synthesis
Status: ACTIVE_NOT_RECRUITING
Conditions: Effect of Food Supplement
Interventions: DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: Hydrolized Collagen|DIETARY_SUPPLEMENT: PrimaColl|DIETARY_SUPPLEMENT: Whey protein
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Oral Thalidomide and Tegafur-uracil to Decrease Hepatocellular Carcinoma Recurrence
Status: COMPLETED
Conditions: Adult Hepatocellular Carcinoma|Recurrent Hepatocellular Carcinoma|Adverse Reaction to Drug|Vascular Endothelial Growth Factor Overexpression
Interventions: DRUG: thalidomine|DRUG: tegafur-uracil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE) and Short Laryngologic Surgery
Status: COMPLETED
Conditions: Laryngologic Surgical Procedures
Interventions: DEVICE: THRIVE|DEVICE: Endotracheal tube
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Meal-based Comparison of Protein Quality, Complementary Proteins and Muscle Anabolism
Status: COMPLETED
Conditions: Protein|Diet|Skeletal Muscle
Interventions: OTHER: PRO-A|OTHER: PRO-B|OTHER: PRO-C
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Safety Study of Sirolimus and Hydroxychloroquine in Women With Lymphangioleiomyomatosis
Status: COMPLETED
Conditions: Lymphangioleiomyomatosis
Interventions: DRUG: "Sirolimus" and "Hydroxychloroquine" 200 mg|DRUG: "Sirolimus" and "Hydroxychloroquine" 400 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic and Pharmacodynamic Assessment of Treatment With CPX-351 (Cytarabine: Daunorubicin) Liposome for Injection in Acute Leukemias and MDS Patients With Moderate Hepatic Impairment
Status: WITHDRAWN
Conditions: Acute Myeloid Leukemia (AML)|Acute Lymphoblastic Leukemia (ALL)|Myelodysplastic Syndrome (MDS)
Interventions: DRUG: CPX-351
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized, Placebo-controlled Multicenter Trial of Lithium Plus Treatment as Usual (TAU) for Acute Suicidal Ideation and Behavior in Patients With Suicidal Major Depressive Episode
Status: UNKNOWN
Conditions: Suicidal Ideation/Behavior|Depression
Interventions: DRUG: Lithium Carbonate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Left Atrial Isolation by Catheter Ablation in Persistent Atrial Fibrillation With Severe Atrial Fibrosis
Status: NOT_YET_RECRUITING
Conditions: Persistent Atrial Fibrillation
Interventions: PROCEDURE: Left atrial isolation by catheter ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Effects of An AI System on Colonoscopy Quality of Novice Endoscopists
Status: COMPLETED
Conditions: Colonoscopy|Artificial Intelligence|Gastrointestinal Disease|Deep Learning
Interventions: DEVICE: artificial intelligence assistance system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Proof of Concept Study of GSK3640254 in Human Immunodeficiency Virus-1 (HIV-1) Infected Treatment-naive Adults
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: GSK3640254|DRUG: Placebo matching GSK3640254 Mesylate salt
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Enhancement of Macular Pigment Density by Oral Lutein Supplementation
Status: COMPLETED
Conditions: Age-Related Maculopathies
Interventions: DIETARY_SUPPLEMENT: VitaluxPlus®|DIETARY_SUPPLEMENT: Omega 3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of an Investigational Study Drug for Benign Prostatic Hyperplasia (0906-140)
Status: COMPLETED
Conditions: Benign Prostatic Hyperplasia
Interventions: DRUG: MK0906, finasteride / Duration of Treatment: 48 weeks|DRUG: Comparator: placebo / Duration of Treatment: 48 weeks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ultrasound Versus Fluoroscopy-guided Selective Lumbar Nerve Root Injection
Status: COMPLETED
Conditions: Lumbar Radiculopathy
Interventions: PROCEDURE: selective lumbar nerve root injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Adjuvant High-Dose, Sequential Chemotherapy in Treating Patients With Resected Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: BIOLOGICAL: filgrastim|DRUG: cyclophosphamide|DRUG: doxorubicin hydrochloride|DRUG: paclitaxel|DRUG: tamoxifen citrate|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Galantamine Treatment for Nonfluent Aphasia in Stroke Patients
Status: COMPLETED
Conditions: Aphasia|Stroke
Interventions: DRUG: Galantamine|DRUG: Placebo pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: EARLY MOBILIZATION OF INTUBETED PATIENTS IN THE INTENSİVE CARE UNİT AND THE EFFECTS OF EARLY MOBILIZATION ON RESPIRATORY PATTERN AND PATIENT HEMODYNAMICS
Status: UNKNOWN
Conditions: Intensive Care Unit Acquired Weakness|Intensive Care, Intubated Patient, Early Mobilization, Mobilization, Respiratory Pattern
Interventions: OTHER: MOBILIZATION
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study To Evaluate Safety And Therapeutic Activity Of RO6874281 In Combination With Pembrolizumab, In Participants With Advanced Or Metastatic Melanoma
Status: COMPLETED
Conditions: Metastatic Melanoma
Interventions: DRUG: RO6874281|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Expandable and Fixed Size Cryoballoon for the Treatment of Paroxysmal Atrial Fibrillation
Status: RECRUITING
Conditions: Atrial Fibrillation
Interventions: DEVICE: cryoballoon pulmonary vein isolation (Medtronic 4th gen balloon)|DEVICE: cryoballoon pulmonary vein isolation (Boston 2nd gen balloon)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Prucalopride on Gastric Emptying in Intensive Care Unit Patients
Status: COMPLETED
Conditions: Enteral Feeding Intolerance
Interventions: DRUG: Prucalopride|DRUG: Metoclopramide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Immune Response to the ASP7373 and Its Safety in Healthy Adult Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: BIOLOGICAL: ASP7373|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study on the Effectiveness of Tuina in Managing Chronic Low Back Pain
Status: UNKNOWN
Conditions: Chronic Low-back Pain
Interventions: OTHER: Physiotherapy|OTHER: Tuina therapy|OTHER: Physio and Tuina therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Scalable Model for Promoting Functioning and Well-Being Among Older Adults With Mild Cognitive Impairment Via Meaningful Social Interactions: Project SPEAK!
Status: COMPLETED
Conditions: Mild Cognitive Impairment
Interventions: OTHER: Intervention (videoconferencing)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Trametinib Plus Anlotinib in Non-G12C KRAS-Mutant NSCLC Patients
Status: COMPLETED
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: Trametinib|DRUG: Anlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trabectedin in Combination With Olaparib in Advanced Unresectable or Metastatic Sarcoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Sarcoma|Sarcoma Metastatic
Interventions: DRUG: Olaparib|DRUG: Trabectedin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Doxorubicin-loaded Anti-EGFR-immunoliposomes (C225-ILs-dox) in High-grade Gliomas
Status: COMPLETED
Conditions: Glioblastoma
Interventions: DRUG: C225-ILs-dox
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Investigating the Novel Observation of Right-left Difference in Uterine Artery Vascular Resistance in Pre-eclampsia
Status: WITHDRAWN
Conditions: Pre-eclampsia
Interventions: DRUG: Epidural lidocaine|DRUG: Epidural lidocaine 2%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT