pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: The Opioid-sparing Effect and Reduced PONV Using Propacetamol in PCA Among Patients With High Risk of PONV
Status: COMPLETED
Conditions: PONV|Propacetamol
Interventions: DRUG: Propacetamol|DRUG: PCA regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of GSK134612 in Subjects Previously Vaccinated Against Meningococcal Disease Versus Non-vaccinated Subjects
Status: COMPLETED
Conditions: Infections, Meningococcal
Interventions: BIOLOGICAL: Meningococcal vaccine GSK134612 (Nimenrix)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Sirolimus or Vorinostat and Hydroxychloroquine in Advanced Cancer
Status: COMPLETED
Conditions: Advanced Cancers
Interventions: DRUG: Hydroxychloroquine|DRUG: Sirolimus|DRUG: Vorinostat
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SATELLITE Study (feaSibility sAfeTy Efficacy dostarLimab earLy-stage defIcient endomeTrial cancEr)
Status: NOT_YET_RECRUITING
Conditions: Endometrial Cancer Stage I|Mmr Deficiency|Endometrioid Endometrial Adenocarcinoma|Immune-related Adverse Event
Interventions: DRUG: Dostarlimab-Gxly 50 MG/1 ML Intravenous Solution [JEMPERLI]
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cohort Study of Prospective Validation of Predictive Factors and Biological Imaging of Response to Bevacizumab and Paclitaxel in Patients With Metastatic Breast Cancer
Status: COMPLETED
Conditions: Metastatic|Breast Cancer
Interventions: DRUG: Bevacizumab|DRUG: paclitaxel
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Home-based Intermittent Pneumatic Compression Therapy for Gynecologic Cancer
Status: COMPLETED
Conditions: Gynecologic Cancer|Lymphedema of Leg
Interventions: DEVICE: home-based intermittent pneumatic compression (IPC) device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess Epidural Resiniferatoxin for the Treatment of Intractable Pain Associated With Advanced Cancer
Status: SUSPENDED
Conditions: Pain, Intractable|Pain Cancer|Pain
Interventions: DRUG: Resiniferatoxin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Volar Plate Injury: A Comparison of Two Splinting Methods
Status: COMPLETED
Conditions: Volar Plate Injury of the Proximal Interphalangeal Joint
Interventions: DEVICE: Thermoplastic splinting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Different Local Anesthetic Volumes for TPVB in Post-thoracotomy Analgesia
Status: RECRUITING
Conditions: Thoracic Paravertebral Block|Thoracotomy|Postoperative Analgesia|Acute Pain|Local Anesthetic
Interventions: PROCEDURE: TPVB with 20 ml|PROCEDURE: TPVB with 25 ml|PROCEDURE: TPVB with 30 ml
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Repeated Endocardial Mapping for Efficacy Assessment After Catheter Ablation for Ischemic Ventricular Tachycardia
Status: ENROLLING_BY_INVITATION
Conditions: Ischemic Cardiomyopathy|Ventricular Tachycardia
Interventions: PROCEDURE: Catheter ablation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Different Exercise Training Modalities in Alpha-1 Antitrypsin Deficiency Patients
Status: UNKNOWN
Conditions: Chronic Obstructive Pulmonary Disease|Alpha 1-Antitrypsin Deficiency
Interventions: PROCEDURE: Exercise training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics of Daunorubicin in Young Patients With Cancer
Status: COMPLETED
Conditions: Unspecified Childhood Solid Tumor, Protocol Specific
Interventions: OTHER: pharmacological study|PROCEDURE: dual x-ray absorptimetry
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Transcranial Direct Current Stimulation Combined Sensory Modulation Intervention in Chronic Stroke Patients
Status: COMPLETED
Conditions: Stroke
Interventions: DEVICE: tDCS|DRUG: Epidermis anesthesia|DRUG: sham anesthesia|OTHER: Repeated passive movement|DEVICE: sham tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparative Study of Two Endoscopic Operations for Lacrimal Duct Obstruction
Status: COMPLETED
Conditions: Lacrimal Duct Obstruction
Interventions: PROCEDURE: Recessive Spherical Headed Silicone Intubation|PROCEDURE: Dacryocystorhinostomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Single Use Flexible Optical Scope Versus Multiple Use Flexible Optical Scopes for Intubation
Status: COMPLETED
Conditions: Tracheal Intubation|Difficult Airway
Interventions: PROCEDURE: tracheal intubation with a single use flexible videoscope
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Autologous Bone Marrow-Derived Stem Cell Therapy for Motor Neuron Disease
Status: UNKNOWN
Conditions: Motor Neuron Disease|Amyotrophic Lateral Sclerosis|Primary Lateral Sclerosis|Progressive Muscular Atrophy|Progressive Bulbar Palsies
Interventions: BIOLOGICAL: Stem Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Micronized dHACM vs. Saline in the Treatment of Osteoarthritis of the Knee
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: BIOLOGICAL: Micronized dHACM|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mind-Body Rehabilitative Program for Veterans With mTBI (Mild Traumatic Brain Injury)
Status: COMPLETED
Conditions: Sleep Disturbance|Traumatic Brain Injury
Interventions: BEHAVIORAL: Mind-Body Bridging Program|BEHAVIORAL: Supportive Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Camrelizumab Plus Chemotherapy in Triple Negative Breast Cancer
Status: RECRUITING
Conditions: Triple Negative Breast Cancer (TNBC)
Interventions: DRUG: Camrelizumab|DRUG: Doxorubicin|DRUG: Cyclophosphamide|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Histomorphometric and Tomographic Assessment on the Influence of the Placement of a Collagen Membrane Subjacent the Sinus Mucosa After Maxillary Sinus Floor Augmentation
Status: COMPLETED
Conditions: Alveolar Bone Loss
Interventions: PROCEDURE: Maxillary sinus augmentation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: RNA-Immunotherapy of IVAC_W_bre1_uID and IVAC_M_uID
Status: COMPLETED
Conditions: Breast Cancer (Triple Negative Breast Cancer (TNBC))
Interventions: BIOLOGICAL: IVAC_W_bre1_uID|BIOLOGICAL: IVAC_W_bre1_uID/IVAC_M_uID
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Observational Study on Renal Function in Kidney Transplant Participants on Immunosuppressive Therapy Containing Mycophenolate Mofetil
Status: COMPLETED
Conditions: Kidney Transplantation
Interventions: DRUG: Mycophenolate Mofetil|DRUG: Immunosuppressive Therapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Autonomic Activity During Nap Under Hypoxia
Status: COMPLETED
Conditions: Hypoxia|Sleep|Healthy
Interventions: OTHER: Normoxia|OTHER: Hypoxia 1|OTHER: Hypoxia 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effectiveness, Safety, Adherence, and Health-related Quality of Life in HIV-1 Infected Adults Receiving Bictegravir/ Emtricitabine/Tenofovir Alafenamide (B/F/TAF)
Status: COMPLETED
Conditions: HIV-1-infection
Interventions: OTHER: B/F/TAF
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Everolimus in Combination With Cyclosporine Microemulsion in de Novo Renal Transplant Recipients
Status: COMPLETED
Conditions: Transplantation Infection
Interventions: DRUG: Everolimus 0.25 and 0.75 mg tablets|DRUG: Cyclosporine very low dose (150-300 ng/mL) microemulsion|DRUG: Cyclosporine low dose (350-500 ng/mL) microemulsion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Hemodynamic Effects of PACAP38 After Glibenclamide Administration in Healthy Volunteers
Status: COMPLETED
Conditions: Migraine|Headache|Pain
Interventions: DRUG: glibenclamide|DRUG: PACAP38
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Efficacy of Alendronate Versus Placebo in the Treatment of HIV-associated Osteoporosis (ANRS120)
Status: COMPLETED
Conditions: Osteoporosis|HIV Infections
Interventions: DRUG: Alendronate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Feasibility Non-inferiority Clinical Trial for Dosing of Diuretics in CHF Patients
Status: UNKNOWN
Conditions: Congestive Heart Failure
Interventions: COMBINATION_PRODUCT: Random dosage and time of furosemide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Helmet Type, Home-use Low-level Light Therapy Device for Chemotherapy-induced Alopecia
Status: RECRUITING
Conditions: Breast Cancer|Chemotherapy-induced Alopecia
Interventions: DEVICE: low-level light therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Extension Study Investigating the Long-Term Safety and Tolerability of Repeat Doses of FE200486 in Prostate Cancer Patients
Status: TERMINATED
Conditions: Prostate Cancer
Interventions: DRUG: Degarelix|DRUG: Degarelix|DRUG: Degarelix|DRUG: Degarelix|DRUG: Degarelix|DRUG: Degarelix|DRUG: Degarelix|DRUG: Degarelix
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Perioperative Intravenous Lidocaine Infusion on Postoperative Recovery in Patients Undergoing Arthroscopic Rotator Cuff Repair Under General Anesthesia
Status: COMPLETED
Conditions: Rotator Cuff Tears
Interventions: DRUG: Lidocaine|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Ovarian Tissue Cryopreservation and Subsequent Auto-Transplantation for Female Cancer Patients (HKCH)
Status: RECRUITING
Conditions: Neoplasms
Interventions: OTHER: Ovarian Tissue Cryopreservation and Subsequent Auto-Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effectiveness of Bilateral PTNS Compared to Unilateral PTNS for the Treatment of Overactive Bladder/Urge Incontinence
Status: RECRUITING
Conditions: Overactive Bladder Syndrome|Urinary Incontinence, Urge
Interventions: DEVICE: PTNS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 1/2a Study to Assess the Safety and Efficacy of CKD-516 Tab. in Combination With Irinotecan Inj.
Status: UNKNOWN
Conditions: Colorectal Cancer
Interventions: DRUG: CKD-516 Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Safety and Biological Activity of AMX0035 for the Treatment of Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer Disease
Interventions: DRUG: AMX0035|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Exoskeleton-Assisted Gait Training on Functional Rehabilitation Outcomes in Patients With Stroke
Status: RECRUITING
Conditions: Stroke|Weakness of Extremities as Sequela of Stroke
Interventions: DEVICE: Indego Exoskeleton|OTHER: Standard Rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Therapy of Darolutamide Plus ADT for High Risk Prostate Cancer
Status: RECRUITING
Conditions: Prostate Cancer
Interventions: DRUG: Darolutamide|DRUG: Goserelin 3.6 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioavailability Study of Lozanoc™ 65 mg Itraconazole Capsules in Patients Requiring Prophylaxis
Status: COMPLETED
Conditions: Neutropenia
Interventions: DRUG: Lozanoc
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Exploring the Relationship Between the Gut Microbiome, Physical Fitness Levels and Metabolic Responses to Exercise
Status: COMPLETED
Conditions: Elite Cyclists|Elite Soccer Players|Sedentary Behavior
Interventions: DIAGNOSTIC_TEST: Maximal incremental exercise test|DIAGNOSTIC_TEST: Submaximal exercise test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Laparoscopic Partial Nephrectomy for cT1 Tumors
Status: COMPLETED
Conditions: Renal Cancer|Renal Neoplasm|Renal Cell Carcinoma|Surgery|Surgery--Complications|Renal Functional Abnormality|Oncology|Oncology Problem|Kidney Ischemia|Kidney Injury|Urologic Neoplasms|Urologic Cancer|Kidney Neoplasms
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study Comparing a Shorter Exposure of Oocyte to Spermatozoa Versus a Standard Incubation on the Live Birth Rate of In-vitro Fertilization Treatment
Status: UNKNOWN
Conditions: Fertility|In Vitro Fertilization
Interventions: PROCEDURE: a shorter exposure of oocyte to spermatozoa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Coadministration of Calcitonin and Hyperbaric Bupivacaine in Spinal Anesthesia in Tramadol-abuse Patients
Status: COMPLETED
Conditions: Analgesia
Interventions: DRUG: Calcitonin presented as Miacalcic® ampoules 100 IU/ml (1ml) intrathecally|DRUG: Calcitonin presented as Miacalcic® ampoules 100 IU/ml (1ml) intravenously|OTHER: Normal Saline (NS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Impact of Triclosan-coated Suture on Surgical Site Infection After Colorectal Surgery
Status: COMPLETED
Conditions: Colorectal Resection
Interventions: DEVICE: Triclosan coated suture|DEVICE: regular suture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Qualitative Techniques to Define Meaningful Within-Patient Change in Symptoms of Advanced Cancer Patients
Status: ENROLLING_BY_INVITATION
Conditions: Hematopoietic and Lymphoid System Neoplasm|Malignant Solid Neoplasm
Interventions: OTHER: Non-Interventional Study
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Predicting Fluid Responsiveness Using Transiently Increased Intrathoracic Pressure in Mechanically Ventilated Patients
Status: COMPLETED
Conditions: Fluid Reponsiveness
Interventions: PROCEDURE: Increase in intrathoracic pressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Health Education on Female Teachers' Knowledge and Practices Regarding Early Breast Cancer Detection and Screening in the Jazan Area: A Quasi-Experimental Study
Status: COMPLETED
Conditions: Effect of Health Education Regarding Screening Tools of Breast Cancer
Interventions: OTHER: Health education|OTHER: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Impact of Cotrimoxazole Prophylaxis for HIV-Infected Adults on Antifolate Resistance
Status: COMPLETED
Conditions: HIV|Malaria|Diarrhea|Pneumonia|Opportunistic Infections
Interventions: DRUG: Cotrimoxazole (trimethoprim sulfamethoxazole)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: ECT
Clinical trial: Optimal Dose of Acetylsalicylic Acid After Coronary Artery Bypass Grafting
Status: COMPLETED
Conditions: Coronary Artery Bypass Surgery|Stable Angina
Interventions: DRUG: Acetylsalicylic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BIP CVC in Access Center at Danderyd Hospital, Stockholm, Sweden
Status: TERMINATED
Conditions: Vascular Access Complication|Catheter-Related Infections|Catheter Thrombosis|Catheter Blockage|Catheter Complications|Catheter Site Discomfort|Catheter Bacteraemia
Interventions: DEVICE: BIP CVC|DEVICE: Standard CVC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety, Tolerability, Patient Satisfaction and Cost of 16.5% Subcutaneous Immunoglobulin (Cutaquig®) Treatment
Status: UNKNOWN
Conditions: Primary Immunodeficiency Disease|Secondary Immunodeficiency
Interventions: DRUG: 16,5% Cutaquig
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Change of Bone Markers After Low Dose Alendronate in Postmenopausal Women With Bone Loss
Status: COMPLETED
Conditions: Osteoporosis
Interventions: DRUG: Alendronate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of CEP-9722 in Combination With Gemcitabine and Cisplatin in Patients With Advanced Solid Tumors or Mantle Cell Lymphoma
Status: COMPLETED
Conditions: Solid Tumors or Mantle Cell Lymphoma
Interventions: DRUG: CEP-9722|DRUG: Gemcitabine|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Determination of Autonomic Responses to the Exposure of Low Energy Electromagnetic Fields With Frequency Modulation in Patients With Advanced Hepatocellular Carcinoma and Healthy Individuals.
Status: RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: OTHER: measuring hemodynamic parameters heart beat to heart beat during single-frequency exposure
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study in Three-arm of Lurbinectedin (PM01183) Alone or in Combination With Gemcitabine and a Control Arm With Docetaxel as Second Line Treatment in Non-Small Cell Lung Cancer (NSCLC) Patients
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer (NSCLC)
Interventions: DRUG: Docetaxel|DRUG: Gemcitabine|DRUG: Lurbinectedin (PM01183)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pembrolizumab Plus Pemetrexed for Elderly Patients With Non-Sq NSCLC With PD-L1 < 50%: CJLSG1901
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-squamous Non-small-cell Lung Cancer|Cancer, Lung
Interventions: DRUG: Pembrolizumab|DRUG: Pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Postoperative Hyponatremia - Are There Gender Differences?
Status: UNKNOWN
Conditions: Hyponatremia
Interventions: PROCEDURE: Fluid administration|PROCEDURE: Perioperative fluid management based on Lean Body Mass
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Development of a Database to Investigate Digital and Blood-Based Biomarkers and Their Relationship to Tau and Amyloid PET Imaging in Older Participants Who Are Cognitively Normal (CN), Have Mild Cognitive Impairment (MCI), or Have Mild-to-Moderate AD Dementia
Status: NOT_YET_RECRUITING
Conditions: Mild Cognitive Impairment|Alzheimer's Disease|Alzheimer's Disease, Early Onset|Memory Loss|Memory Disorders|Memory Impairment
Interventions: OTHER: Biomarker Data Collection|RADIATION: MK6240
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Local Effects of Acupuncture and Nerve Conduction Studies
Status: COMPLETED
Conditions: Carpal Tunnel Syndrome
Interventions: DEVICE: MAC acupuncture needles|DEVICE: Electrostimulator 6c.Pro, Pantheon Research, Venice, CA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Drug-drug Interaction Between Rifampicin and Progestins/Ethinylestradiol and Midazolam
Status: COMPLETED
Conditions: Biological Availability
Interventions: DRUG: levonorgestrel/ Microlut|DRUG: Norethindrone/ Noriday|DRUG: Desogestrel/ Cerazette|DRUG: Dienogest/ Visanne|DRUG: Drospirenone, Ethinylestradiol/ Yasmin|DRUG: Midazolam/ Midazolam-ratiopharm|DRUG: Rifampicin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Effect of New Zealand Blackcurrant (NZBC) Supplementation on Recovery Following Strenuous Exercise
Status: COMPLETED
Conditions: Muscle Damage
Interventions: DIETARY_SUPPLEMENT: New Zealand blackcurrants (NZBC)|DIETARY_SUPPLEMENT: Placebo (PLA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Phase I Study of Temozolomide, Valproic Acid and Radiation Therapy in Patients With Brain Metastases
Status: TERMINATED
Conditions: Brain Metastases
Interventions: DRUG: Temozolomide|DRUG: Valproic Acid|PROCEDURE: Whole Brain Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CSD170401: Study to Assess Elements of Abuse Liability for Three Electronic Tobacco Vapor Products During an 11-Day In-Clinic Confinement
Status: COMPLETED
Conditions: Smoking
Interventions: OTHER: Product A|OTHER: Product B|OTHER: Product C|OTHER: Product D|OTHER: Product E
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Desidustat in the Treatment of Anemia in CKD
Status: COMPLETED
Conditions: Chronic Kidney Disease Stage 3|Anemia|Chronic Kidney Disease Stage 4|Chronic Kidney Disease Stage 5
Interventions: DRUG: Desidustat Oral Tablet|DRUG: Darbepoetin Alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intensive TMS for Bipolar Depression
Status: COMPLETED
Conditions: Bipolar Depression|Treatment Resistant Depression
Interventions: DEVICE: Intensive intermittent theta-burst stimulation (iTBS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Study of the Adverse Events and Change in Disease State of Pediatric Participants (and Young Adults Between the Ages of 18-25) With Relapsed/Refractory Aggressive Mature B-cell Neoplasms Receiving Subcutaneous (SC) Injections of Epcoritamab
Status: RECRUITING
Conditions: Non-hodgkin Lymphoma
Interventions: DRUG: Epcoritamab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Surgical Treatment of Adrenal Diseases- Laparoscopic vs. Robotic-assisted Adrenalectomy
Status: RECRUITING
Conditions: Adrenal Tumor|Adrenal Disease|Adrenal Mass|Adrenalectomy; Status|Adrenal Hyperplasia|Adrenal Gland Metastasis|Adrenal Cortex Diseases|Pheochromocytoma|Cushing Syndrome|Conn Adenoma|Adrenocortical Carcinoma|Adrenocortical Adenoma|Adrenocortical Tumor
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Personalized Adaptive Radiation Therapy With Individualized Systemic Targeted Therapy (PARTIST) for Locally Advanced, Non-small Cell Lung Cancer With Genomic Driver Mutations
Status: WITHDRAWN
Conditions: Non-Small Cell Lung Cancer
Interventions: RADIATION: PET-Adaptive RT|DRUG: Erlotinib|DRUG: Crizotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neotech RAM Cannula Versus Conventional Binasal Prong Continuous Positive Airway Pressure (CPAP) to Treat Respiratory Distress in Low Birth Weight Neonates
Status: TERMINATED
Conditions: Respiratory Distress Syndrome, Newborn|Continuous Positive Airway Pressure|Low Birth Weight Infants
Interventions: DEVICE: RAM Cannula|DEVICE: Binasal Prong CPAP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Sorafenib in Children and Young Adults With Recurrent or Progressive Low-Grade Astrocytomas
Status: TERMINATED
Conditions: neurofibromatosis1 (NF1)|Recurrent or Progressive Optic Pathway Gliomas (OPG)|Recurrent or Progressive Low-grade Glioma
Interventions: DRUG: Sorafenib (Nexavar)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Using Intravitreal Injections of a Small Interfering RNA in Patients With Age-Related Macular Degeneration
Status: TERMINATED
Conditions: Choroid Neovascularization|Age-Related Macular Degeneration
Interventions: DRUG: AGN 211745|DRUG: AGN 211745|DRUG: AGN 211745|DRUG: Ranibizumab 500µg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: First Strike, Second Strike Therapies for High Risk Metastatic Castration Sensitive Prostate Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Cancer|Stage IV Prostate Cancer
Interventions: DRUG: Luteinizing Hormone Releasing Hormone|DRUG: New Hormonal Agent|DRUG: Docetaxel|DRUG: Tislelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Transcutaneous and Percutaneous PTNS on Idiopathic OAB
Status: COMPLETED
Conditions: Overactive Bladder|Urge Incontinence|Overactive Detrusor
Interventions: DEVICE: PTNS|DEVICE: TENS SNS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MAIN STUDY: Low Glycaemic Index (GI) Diet in the Management of GDM SUB-STUDY: The Breast Milk Sub-Study
Status: COMPLETED
Conditions: Gestational Diabetes Mellitus
Interventions: OTHER: Standard Care|OTHER: Low GI diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Physical Condition and Bariatric Surgery
Status: UNKNOWN
Conditions: Obese Patients With Bariatric Surgery
Interventions: BEHAVIORAL: Physical activity program : aquabike|BEHAVIORAL: Physical activity program : bicycle|BEHAVIORAL: Physical activity program : with protein supplementation|BEHAVIORAL: Physical activity program : without protein supplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Multicenter Study to Evaluate the ROX Anastomotic Coupler System (ACS) In Patients With Severe Hypertension
Status: COMPLETED
Conditions: Hypertension
Interventions: DEVICE: ROX ANASTOMOTIC COUPLER SYSTEM (ACS)|DEVICE: ROX Anastomotic Coupler System (ACS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Post-marketing Surveillance Study of Ex-intravenous Drug Abusers With Chronic Hepatitis C Treated With PegIntron Plus Rebetol (P04408/MK-4031-261)
Status: COMPLETED
Conditions: Hepatitis C, Chronic|Substance Abuse, Intravenous
Interventions: BIOLOGICAL: PegIntron (pegylated interferon alfa-2b; SCH 54031)|DRUG: Rebetol (ribavirin; SCH 18908)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Levofloxacin Triple and Bismuth Quadruple Therapies for Rescue Treatment of H Pylori Infection
Status: COMPLETED
Conditions: Helicobacter Pylori Infection
Interventions: DRUG: esomeprazole+amox+levo|DRUG: esomeprazole+bismuth+tetra+levo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Randomized Trial of CPAP for SDB in Patients Who Use Opioids
Status: RECRUITING
Conditions: Sleep Disorder; Breathing-Related|Pain|Sleep Apnea|Obstructive Sleep Apnea|Sleep|Sleep Disorder|Chronic Pain|Opioid Use
Interventions: DEVICE: Positive Airway Pressure (PAP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cytoreductive Surgery and Transarterial Chemoembolization (TACE) Versus TACE for Hepatocellular Carcinoma
Status: COMPLETED
Conditions: Hepatocellular Carcinoma
Interventions: PROCEDURE: Cytoreductive Surgery|PROCEDURE: TACE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improving Neurological Health in Aging Via Neuroplasticity-based Computerized Exercise
Status: COMPLETED
Conditions: Healthy Aging
Interventions: OTHER: Computerized Plasticity-Based Adaptive Cognitive Training|OTHER: Commercially available computerized training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 3 Clinical Effect Durability of TD-9855 for Treating Symptomatic nOH in Subjects With Primary Autonomic Failure
Status: TERMINATED
Conditions: Symptomatic Neurogenic Orthostatic Hypotension|MSA|Parkinson's Disease (PD)|Pure Autonomic Failure (PAF)
Interventions: DRUG: ampreloxetine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of the Efficacy of Bevacizumab in Combination With Folfiri as Second-line Treatment in Patients Suffering From an Advanced Inoperable Poorly Differentiated Neuroendocrine Carcinoma of an Unknown or Gastroentero-pancreatic Primary Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Neuroendocrine Carcinomas
Interventions: DRUG: Folfiri-bevacizumab|DRUG: Folfiri
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Minimal Access Versus Conventional Latissimus Dorsi Flap Harvest for Breast Reconstruction
Status: RECRUITING
Conditions: Breast Neoplasms
Interventions: DEVICE: minimal access breast reconstruction with a latissimus dorsi muscle flap|DEVICE: conventional breast reconstruction with a latissimus dorsi muscle flap
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral Sulopenem Versus Amoxicillin/Clavulanate for Uncomplicated Urinary Tract Infection in Adult Women
Status: COMPLETED
Conditions: Urinary Tract Infections|Cystitis
Interventions: DRUG: Sulopenem etzadroxil/probenecid|DRUG: Amoxicillin/clavulanate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Annexin A5 in Patients With Severe COVID-19 Disease
Status: COMPLETED
Conditions: Coronavirus Infection|Sepsis
Interventions: DRUG: recombinant human annexin A5|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: EMR Chemotoxicity Risk Calculator To Decrease Chemotherapy Toxicity
Status: COMPLETED
Conditions: Oncology|Chemotherapeutic Toxicity|Metastatic Solid Tumor
Interventions: OTHER: Chemotherapy toxicity tool|OTHER: Oncology Consultation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Effect of Extracorporeal Shock Wave Therapy of Gastrosoleus Trigger Points in Patients With Plantar Fasciitis
Status: UNKNOWN
Conditions: Plantar Fasciitis
Interventions: PROCEDURE: Extracorporeal shock wave therapy 1|PROCEDURE: Extracorporeal shock wave therapy 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: FFR and Inducible Myocardial Ischemia During Adenosine Stress Testing
Status: UNKNOWN
Conditions: Coronary Artery Stenosis
Interventions: DIAGNOSTIC_TEST: Fractional flow reserve with adenosine stress testing
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluating the Risk of Serious Ventricular Arrhythmia and Sudden Cardiac Death Among Users of Domperidone
Status: COMPLETED
Conditions: Arrhythmias, Cardiac
Interventions: OTHER: No Intervention|DRUG: Current Domperidone|DRUG: Current proton pump inhibitor (PPI)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phase 4 Efficacy and Safety Study of Cubicin® With and Without Combination Therapy in S. Aureus Infective Endocarditis (SAIE)
Status: TERMINATED
Conditions: Infective Endocarditis
Interventions: DRUG: daptomycin|DRUG: daptomycin and gentamicin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: MARY DUOL REPAIR BALM IN THE PREVENTION OR REDUCING ANTINEOPLASIC AGENTS' SKIN TOXICITY
Status: UNKNOWN
Conditions: Dermatitis, Adverse Drug Reaction
Interventions: PROCEDURE: BALM ARM|PROCEDURE: PLACEBO ARM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: CNI-free de Novo Protocol in Patients Undergoing Liver Transplantation With Renal Impairment
Status: COMPLETED
Conditions: End Stage Liver Disease|Impaired Renal Function
Interventions: DRUG: anti-CD 25 mAb, Sirolimus, MMF
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bilateral Priming Plus Task Specific Training for Severe Upper Limb Hemiparesis
Status: ACTIVE_NOT_RECRUITING
Conditions: Stroke
Interventions: BEHAVIORAL: Bilateral Motor Priming + Task Specific Training (BMP + TST)|BEHAVIORAL: Control Priming + TST (CP + TST)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of CNTX-4975 in Subjects With Painful Intermetatarsal Neuroma (Morton's Neuroma)
Status: COMPLETED
Conditions: Painful Intermetatarsal Neuroma (Morton's Neuroma)
Interventions: DRUG: CNTX-4975|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: FHD-286 as Monotherapy or Combination Therapy in Subjects With Advanced Hematologic Malignancies
Status: RECRUITING
Conditions: Advanced Hematologic Malignancy|Relapsed Acute Myeloid Leukemia|Refractory Acute Myeloid Leukemia|Relapsed Myelodysplastic Syndromes|Refractory Myelodysplastic Syndromes|Relapsed Chronic Myelomonocytic Leukemia|Refractory Chronic Myelomonocytic Leukemia
Interventions: DRUG: FHD-286|DRUG: Low Dose Cytarabine|DRUG: Decitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of an Operating Room Nurse Pre-operative Dialogue in Patients Undergoing Major Visceral Surgery
Status: COMPLETED
Conditions: Anxiety|Post Operative Pain|Postoperative Nausea|Postoperative Complications|Satisfaction, Patient
Interventions: BEHAVIORAL: Preoperative nurse dialogue
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effectiveness and Implementation of mPATH-CRC
Status: COMPLETED
Conditions: Colorectal Cancer|Cancer|Rectum Cancer|Colon Cancer
Interventions: OTHER: mPATH-CRC|OTHER: mPATH-Checkin|OTHER: "high touch" Implementation strategy|OTHER: "low touch" Implementation Strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Pilot Study to Assess the Feasibility and Initial Efficacy of Therapist-as-consultant, Game-based CI Therapy
Status: COMPLETED
Conditions: Stroke|Hemiparesis|Upper Extremity Dysfunction
Interventions: BEHAVIORAL: Hemiparesis Therapy with VR
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety of a Tetravalent Dengue Vaccine Administered Concomitantly or Sequentially With Gardasil®
Status: COMPLETED
Conditions: Dengue Fever|Dengue Hemorrhagic Fever|Human Papillomavirus Disease
Interventions: BIOLOGICAL: CYD Dengue Vaccine|BIOLOGICAL: CYD Dengue Vaccine|BIOLOGICAL: Human Papillomavirus Quadrivalent [Types 6, 11, 16, and 18] Vaccine, Recombinant.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effect of Ketamine on Interleukin-6 Synthesis in Hepatic Resections Requiring Temporary Porto-arterial Occlusion
Status: COMPLETED
Conditions: Hepatectomy
Interventions: DRUG: Ketamine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of a Muscle-mimicking, Fabric-type Shoulder Orthosis on Functional Movements of the Upper Limb in Patients With Duchenne Muscular Dystrophy
Status: RECRUITING
Conditions: Muscular Dystrophy, Duchenne|Orthotic Devices|Upper Extremity
Interventions: DEVICE: Shoulder orthosis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Accuracy and Reliability of Fetal Heart Rate and Uterine Contraction Monitoring Method
Status: COMPLETED
Conditions: Pregnancy; Habitual Aborter|Weeks of Gestation 37 or More
Interventions: DEVICE: Monica AN24 (K101081)|DEVICE: Philips 50XM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation of the Inter-center Variability of the Measurement of Thrombin Generation by the ST Genesia System
Status: COMPLETED
Conditions: Patients Without a Medical History of Thrombosis or Hemorrhage|Hemophilic Patient|Patient With FV Leiden Mutation|Patient With Cirrhosis|Patient on Anticoagulant
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of the Impact of a Therapeutic Education Program for Children With Type 1 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type I|Program Evaluation|Therapeutic Education|Children
Interventions: OTHER: DIAPASON Questionnaire|BEHAVIORAL: WHO-5
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Suture Contamination Rate in Adjustable Suture Strabismus Surgery
Status: COMPLETED
Conditions: Suture Strabismus Surgery
Interventions: DRUG: 5%povidone iodine ophthalmic solution|DRUG: routine post-operative ophthalmic ointment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Phase 3 Study to Evaluate the Efficacy & Safety of Tralokinumab in Adults & Adolescents With OCS Dependent Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: BIOLOGICAL: Tralokinumab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Plan and Pledge, HIV Self-testing in South Africa
Status: COMPLETED
Conditions: Human Immunodeficiency Virus
Interventions: BEHAVIORAL: Provision of HIV self-test with Commitment and planning prompts|BEHAVIORAL: Provision of HIV self-test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Naturalistic Teaching Strategies in Children With Autism
Status: COMPLETED
Conditions: Autism Spectrum Disorder
Interventions: OTHER: Effect of Naturalistic Teaching Strategies in Children with autism spectrum disorder|OTHER: PECS Therapy only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Aesthetic Outcome of Layered Closure vs. Layered Closure Followed by 2-Octyl Cyanoacrylate
Status: COMPLETED
Conditions: Scarring
Interventions: OTHER: 2-Octyl cyanoacrylate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Microbial Biomarkers of EArly Pseudomonas Aeruginosa Colonization in CHildren With Cystic Fibrosis
Status: ACTIVE_NOT_RECRUITING
Conditions: Cystic Fibrosis
Interventions: DIAGNOSTIC_TEST: collection of expectoration, stools and blood
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of Arginine Free IED in Critically Ill Patients.
Status: COMPLETED
Conditions: Critical Illness
Interventions: DIETARY_SUPPLEMENT: Immunoenhancing diet|DIETARY_SUPPLEMENT: Isocaloric, isonitrogenous diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Aflibercept in Treating Patients With Recurrent and/or Metastatic Thyroid Cancer That Did Not Respond to Radioactive Iodine Therapy
Status: COMPLETED
Conditions: Recurrent Thyroid Gland Carcinoma|Stage III Thyroid Gland Follicular Carcinoma|Stage III Thyroid Gland Papillary Carcinoma|Stage IV Thyroid Gland Follicular Carcinoma|Stage IV Thyroid Gland Papillary Carcinoma
Interventions: RADIATION: Fludeoxyglucose F-18|OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacological Study|PROCEDURE: Positron Emission Tomography|BIOLOGICAL: Ziv-Aflibercept
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ramucirumab (Cyramza), Nal-IRI (ONIVYDE) and Trifluridine/Tipiracil (Lonsurf) in Second Line Metastatic Gastric Cancer .
Status: NOT_YET_RECRUITING
Conditions: Metastatic Gastric Adenocarcinoma|Second Line|Chemotherapy
Interventions: DRUG: nal-IRI /Experimental|DRUG: Ramucirumab /Experimental|DRUG: Trifluridine/Tipiracil /Experimental
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Hemostatic Agents in Robotic-assisted Laparoscopic Partial Nephrectomy
Status: WITHDRAWN
Conditions: Robotic-Assisted Laparoscopic Partial Nephrectomy|Hemostatic Agents|Renal Malignant Tumor
Interventions: DEVICE: Hemostat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Different Formulations of a Clostridium Difficile Toxoid Vaccine Given at Three Different Schedules in Adults
Status: COMPLETED
Conditions: Clostridium Difficile Infection|Diarrhea
Interventions: BIOLOGICAL: Clostridium difficile toxoids A and B (Low-dose with adjuvant)|BIOLOGICAL: Clostridium difficile toxoids A and B (Low-dose without adjuvant)|BIOLOGICAL: Clostridium difficile toxoids A and B (high-dose with adjuvant)|BIOLOGICAL: Clostridium difficile toxoids A and B (high-dose without adjuvant)|BIOLOGICAL: Placebo: 0.9% normal saline|BIOLOGICAL: Clostridium difficile toxoids A and B (high-dose with adjuvant)|BIOLOGICAL: Clostridium difficile toxoids A and B (high-dose with adjuvant)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION