pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Peer Support Intervention to Mitigate Social Isolation and Stigma of Adolescent Motherhood in Zimbabwe
Status: COMPLETED
Conditions: Mental Health Disorder|Social Isolation|Stigma, Social
Interventions: BEHAVIORAL: Young Women of Today
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of Danoprevir/r + PR 12week Triple Therapy in Treatment Naive Non-Cirrhotic G1 CHC China III
Status: COMPLETED
Conditions: Chronic Hepatitis C
Interventions: DRUG: Danoprevir|DRUG: Ritonavir|DRUG: peginterferon alfa-2a|DRUG: RBV
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long-term Use of Takepron Capsules on the Prevention of Recurrence of Gastric/Duodenal Ulcer in Patients Receiving Low-dose Aspirin
Status: COMPLETED
Conditions: Gastric or Duodenal Ulcers
Interventions: DRUG: Lansoprazole
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Cerebral Blood Flow Effects of Resveratrol and Piperine in Humans
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Trans- resveratrol|OTHER: Placebo (silica)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Dolutegravir-Lamivudine as Dual Therapy in Naive HIV-Infected Patients: A Pilot Study
Status: COMPLETED
Conditions: HIV-1 Infection
Interventions: DRUG: dolutegravir, lamivudine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Market to MyPlate: Investigating the Impact of a Nutrition and Hands-On Cooking Intervention
Status: COMPLETED
Conditions: Fruit and Vegetable Consumption|Cooking Frequency
Interventions: BEHAVIORAL: Nutrition and hands on cooking classes for parents and their children|BEHAVIORAL: Produce allocations
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Transcatheter Exclusion of Atrial-septal-aneurysm (TEA)
Status: UNKNOWN
Conditions: Atrial Septal Aneurysm
Interventions: DEVICE: Transcatheter exclusion of atrial septal aneurysm
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Study of Regional Hemodynamic Changes After Specific Brachial Plexus Block by Ultrasound Guidance
Status: COMPLETED
Conditions: Upper Limb Nerve Block
Interventions: PROCEDURE: specific nerve block|DRUG: ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety/Effectiveness Study of Cysteamine Bitartrate Delayed-release Capsules (RP103) in Cysteamine Treatment Naive Patients With Cystinosis
Status: COMPLETED
Conditions: Cystinosis
Interventions: DRUG: RP103
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Assessment of Chronic Synovial-Based Inflammation and Its Role With Serum Urate Levels.
Status: COMPLETED
Conditions: Gout
Interventions: OTHER: Magnetic Resonance Imaging|DRUG: Febuxostat|DRUG: Colchicine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Neuropeptides in Human Reproduction
Status: COMPLETED
Conditions: Hypogonadotropic Hypogonadism
Interventions: DRUG: Kisspeptin 112-121|DRUG: Naloxone|DRUG: GnRH
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: 9-ING-41 Plus Retifanlimab and Gemcitabine/Nab-Paclitaxel in Patients With Advanced Pancreatic Adenocarcinoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Pancreatic Adenocarcinoma
Interventions: DRUG: 9-ING-41|DRUG: Retifanlimab|DRUG: Gemcitabine|DRUG: Abraxane
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hyperbaric Oxygen Therapy for Renal Regeneration in Diabetic Nephropathy
Status: TERMINATED
Conditions: Chronic Renal Failure
Interventions: OTHER: Hyperbaric Oxygen oxygen therapy (HBOT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Aromatherapy in Women With Primiparous Cesarean Section
Status: ENROLLING_BY_INVITATION
Conditions: Aromatherapy|Cesarean Section Complications|Primiparity|Postpartum Period
Interventions: OTHER: inhaler|OTHER: Control Group|OTHER: massage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: EPIBONE Study: a Prospective Study on Feasibility, Safety and Accuracy
Status: NOT_YET_RECRUITING
Conditions: Bone Metastases|Fractures, Bone|Bone Tumor
Interventions: PROCEDURE: CT-guided bone percutaneous procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Positron Emission Tomography Assessment of the Central Nervous System Effects of Eszopiclone and Zolpidem
Status: WITHDRAWN
Conditions: Healthy
Interventions: DRUG: eszopiclone, zolpidem, placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Oral Ivermectin Versus Topical Permethrin to Treat Scabies in Children and Adults
Status: COMPLETED
Conditions: Scabies
Interventions: DRUG: Ivermectin|DRUG: Permethrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Dipeptide N (2)-L-Alanyl-L-Glutamine in Trauma ICU Patients: Pilot, Prospective, Randomized and Double Blind Study.
Status: UNKNOWN
Conditions: Trauma ICU Patients
Interventions: DRUG: Glutamine|DRUG: Physiological serum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Compare Polyethylene Glycol and Sodium Picosulfate Alone or Combined
Status: UNKNOWN
Conditions: Bowel Preparation
Interventions: DRUG: PEG|DRUG: PEG plus SPMC|DRUG: SPMC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Pilot Study of Pharmaceutical and Behavioral Interventions to Treat Anxiety Disorders
Status: COMPLETED
Conditions: Posttraumatic Stress Disorder|Anxiety Disorder
Interventions: DRUG: Propranolol|BEHAVIORAL: Reactivation|DRUG: Mifepristone|DRUG: Intranasal oxytocin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Intraoperative Small-dose Esketamine Infusion for Pain Control in Burn Patients
Status: UNKNOWN
Conditions: Burns
Interventions: DRUG: Esketamine|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: SOIBD Collagenous Colitis Maintenance Study
Status: COMPLETED
Conditions: Induction and Maintaining Remission of Collagenous Colitis
Interventions: DRUG: Budesonide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Same-day Versus Separate-day Preoperative Consultation for Mohs Surgery
Status: WITHDRAWN
Conditions: Non-melanoma Skin Cancer|Squamous Cell Carcinoma of Skin|Basal Cell Carcinoma
Interventions: OTHER: Same-day preoperative consultation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Comparative Study Between the Efficacy of The Serratus Anterior Plane Block and Lumbar Intrathecal Fentanyl Injection for Postoperative Analgesia After Modified Radical Mastectomy
Status: COMPLETED
Conditions: Patients Undergoing Modified Radical Mastectomy
Interventions: PROCEDURE: Serratus Anterior Plane Block|PROCEDURE: Lumbar Intrathecal Fentanyl Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: "Comparative Clinical Evaluation of Pit and Fissure Sealants on Permanent First Molar Teeth in Children."
Status: COMPLETED
Conditions: PITS AND FISSURE SEALANT
Interventions: DRUG: Sealant, Fissure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Methylprednisolone With or Without Doxorubicin in Treating Patients With Metastatic Prostate Cancer
Status: TERMINATED
Conditions: Prostate Cancer
Interventions: DRUG: doxorubicin hydrochloride|DRUG: methylprednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Yoga Fatigue Study
Status: TERMINATED
Conditions: Acute Myeloid Leukemia (AML)|Acute Lymphocytic Leukemia in Relapse|Burkitt's Lymphoma Stage III|Burkitt's Lymphoma Stage IV|Type 3 Diffuse Large B-Cell Lymphoma
Interventions: BEHAVIORAL: Individualized Yoga Intervention Group|OTHER: iPad Activity Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Multiple Ascending Dose Study to Evaluate the Safety, Tolerability and Pharmacokinetics of BMS-986120 in Healthy Subjects and the Effects of Co-Administration of Midazolam and BMS-986120
Status: COMPLETED
Conditions: Healthy Adult Volunteers
Interventions: DRUG: BMS-986120|DRUG: Placebo|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Safety of Prophylactic Use of an Antibiotic for Medical Thoracoscopy
Status: COMPLETED
Conditions: Pleural Effusion|Pleurisy|Empyema
Interventions: DRUG: Cefazolin|OTHER: saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of Carboplatin, Pemetrexed Plus Placebo vs Carboplatin, Pemetrexed Plus 1 or 2 Truncated Courses of Demcizumab in Subjects With Non-Squamous Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Nonsquamous Nonsmall Cell Neoplasm of Lung
Interventions: DRUG: Pemetrexed|DRUG: Carboplatin|DRUG: demcizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I/IIa Study of AZD8205 Given Alone or in Combination With Anticancer Drugs, in Participants With Advanced or Metastatic Solid Malignancies
Status: RECRUITING
Conditions: Breast Cancer|Biliary Tract Carcinoma|Ovarian Cancer|Endometrial Cancer
Interventions: DRUG: AZD8205|DRUG: AZD8205 and AZD2936 (Rilvegostomig)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SSRIs and TDCS Enhance Post-stroke Motor Recovery
Status: NOT_YET_RECRUITING
Conditions: Stroke|Motor
Interventions: DEVICE: tDCS|DRUG: Citalopram|BEHAVIORAL: Rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Peritoneal Bacterial Contamination Following Resection With Closed or Open Rectal Stump for Left-sided Cancer
Status: COMPLETED
Conditions: Bacterium-Related Malignant Neoplasm
Interventions: PROCEDURE: Closed stump
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose:
Clinical trial: Locoregional Therapy Combined With Bevacizumab and PD1/L1 Inhibitor in Advanced Hepatocellular Carcinoma
Status: RECRUITING
Conditions: Advanced Hepatocellular Carcinoma|Anti-PD1/PDL1 Antibody|Bevacizumab
Interventions: PROCEDURE: Locoregional therapy|DRUG: Bevacizumab|DRUG: Atezolizumab|DRUG: Tislelizumab|DRUG: Toripalimab|DRUG: Sintilimab|DRUG: Camrelizumab
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Impact of SomaSignal Tests on the Choice of Glucose-lowering Medications
Status: ACTIVE_NOT_RECRUITING
Conditions: Type 2 Diabetes|Cardiovascular Diseases
Interventions: BEHAVIORAL: Informed of results from SomaSignal Cardiovascular Risk Test in Type 2 Diabetes (CVD-T2D)|BEHAVIORAL: Not informed of results from SomaSignal Cardiovascular Risk Test in Type 2 Diabetes (CVD-T2D)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Adipose-derived Mesenchymal Stem Cells in Acute Respiratory Distress Syndrome
Status: UNKNOWN
Conditions: ARDS
Interventions: DRUG: Mesenchymal stem cells|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Test the Safety and Tolerability and Pharmacokinetics of Single Doses of UCB0107 in Healthy Japanese Subjects
Status: COMPLETED
Conditions: Healthy Japanese Volunteers
Interventions: DRUG: UCB0107|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study Evaluating the Safety and Efficacy of VX-440 Combination Therapy in Subjects With Cystic Fibrosis
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: TEZ|DRUG: IVA|DRUG: VX-440|DRUG: Matched Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Peri-Implant Healing Around Two Different Machined-Collar Designs After 25 Years of Function
Status: COMPLETED
Conditions: Jaw, Edentulous
Interventions: DEVICE: Brånemark® 2, Swede-Vent® 2, Screw-Vent® 1 (Configuration 1)|DEVICE: Brånemark® 1, Swede-Vent® 2, Screw-Vent® 2 (Configuration 2)|DEVICE: Brånemark® 2, Swede-Vent® 1, Screw-Vent® 2 (Configuration 3)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Oral Health-Related Quality of Life Between Two Different Types of Orthodontic Appliances
Status: COMPLETED
Conditions: Crowding of Anterior Mandibular Teeth
Interventions: DEVICE: A modified aligner appliance with NiTi springs|DEVICE: Conventional fixed appliances
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigation of the Acute Calming Effects of Drinks Containing Herbal Extracts in Healthy Adults
Status: COMPLETED
Conditions: Cognitive Function and Mood
Interventions: OTHER: Herbal Beverage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effectiveness and Cost-effectiveness of Sacral Neuromodulation in Patients With Idiopathic Slow-transit Constipation
Status: COMPLETED
Conditions: Constipation|Surgery
Interventions: DEVICE: Sacral Neuromodulation|OTHER: Personalized Conservative Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Curative Effect Evaluation of Danlou Tablet on Coronary Artery Disease Not Amenable to Revascularization
Status: UNKNOWN
Conditions: Coronary Artery Disease(CAD)
Interventions: DRUG: Danlou Tablet|DRUG: DanLou Tablet placebo|DRUG: Aspirin Enteric-coated Tablets|DRUG: Clopidogrel Hydrogen Sulfate 75 MG Oral Tablet|DRUG: Atorvastatin calcium|DRUG: Isosorbide Mononitrate Tab 20 MG|DRUG: Metoprolol Tartrate Tab 25 MG|DRUG: Trimetazidine Dihydrochloride Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Fludarabine, Cytoxan and FCCAM <Alemtuzumab> in Untreated B-Cell Chronic Lymphocytic Leukemia
Status: COMPLETED
Conditions: Leukemia|B-cell Leukemia|Chronic Leukemia|Chronic Lymphocytic Leukemia (CLL)
Interventions: DRUG: Alemtuzumab|DRUG: Fludarabine|DRUG: Cytoxan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of Information and Relaxation on Pre-procedural Block Anxiety and Procedural Discomfort During Medial Branch Block
Status: COMPLETED
Conditions: Chronic Pain
Interventions: BEHAVIORAL: Relaxation and information session
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Preservation of Fertility by Ovarian Stimulation Associated With Tamoxifen, Prior Chemotherapy for Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Tamoxifen stim in early follicular phase|DRUG: Tamoxifen stim in late follicular phase|DRUG: Tamoxifen stim in luteal phase
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Internet-delivered CBT for Functional Gastrointestinal Disorders (FGID) in Youth: a Single Case Experimental Design
Status: COMPLETED
Conditions: Functional Gastrointestinal Disorders
Interventions: OTHER: Internet delivered cognitive behavioural therapy for functional gastrointestinal disorders
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Contribution of [18F]DPA-714 PET for Grading and Exploration of the Inflammatory Microenvironment of Glioma.
Status: WITHDRAWN
Conditions: Glioma
Interventions: DRUG: [18F]DPA-714
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Ultrasound Guided Peribulbar Anaesthesia - A Novel Dual Quadrant Injection Technique
Status: COMPLETED
Conditions: Eye Diseases
Interventions: PROCEDURE: Ultrasound guided Dual Quadrant Peribulbar Anaesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Decitabine in Treating Patients With Myelodysplastic Syndromes or Acute Myeloid Leukemia
Status: TERMINATED
Conditions: Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities|Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)|Adult Acute Myeloid Leukemia With t(15;17)(q22;q12)|Adult Acute Myeloid Leukemia With t(16;16)(p13;q22)|Adult Acute Myeloid Leukemia With t(8;21)(q22;q22)|Atypical Chronic Myeloid Leukemia, BCR-ABL1 Negative|de Novo Myelodysplastic Syndromes|Myelodysplastic/Myeloproliferative Neoplasm, Unclassifiable|Previously Treated Myelodysplastic Syndromes|Recurrent Adult Acute Myeloid Leukemia|Secondary Acute Myeloid Leukemia|Secondary Myelodysplastic Syndromes|Untreated Adult Acute Myeloid Leukemia
Interventions: DRUG: decitabine|OTHER: laboratory biomarker analysis|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lofexidine for Management of Opioid Withdrawal With XR-NTX Treatment
Status: COMPLETED
Conditions: Opioid-use Disorder
Interventions: DRUG: Lofexidine 0.18 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adding Ruxolitinib to a Combination of Dasatinib Plus Dexamethasone in Remission Induction Therapy in Newly Diagnosed Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia Patients Aged 40 Years or Older
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Lymphoblastic Leukemia
Interventions: DRUG: Ruxolitinib|DRUG: Dasatinib|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral Prednisolone to Prevent Esophageal Stricture After RFA for Long-segment Esophageal Neoplasia
Status: RECRUITING
Conditions: Esophageal Neoplasms|Esophagus Stenosis
Interventions: DRUG: Oral prednisolone (30mg/day) for 28 days
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Circadian Rhythm and Metabolic Effects of Exercise
Status: UNKNOWN
Conditions: Diabetes Mellitus, Type 2|Circadian Rhythm|Glycemic Control
Interventions: BEHAVIORAL: High-intensity Intermittent Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Non-Myeloablative Conditioning for Unrelated Donor Umbilical Cord Blood Transplant
Status: COMPLETED
Conditions: Myeloproliferative Disorders|Leukemia|Lymphoma|Myelodysplastic Syndromes
Interventions: BIOLOGICAL: anti-thymocyte globulin|DRUG: cyclophosphamide|DRUG: Fludarabine|DRUG: mycophenolate mofetil|PROCEDURE: umbilical cord blood transplantation|RADIATION: total body irradiation|DRUG: Sirolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Postprandial Fatty Acid Metabolism in the Natural History of Type 2 Diabetes (T2D)
Status: COMPLETED
Conditions: Impaired Glucose Tolerance
Interventions: DRUG: Nicotinic acid|OTHER: [7,7,8,8-2H]-palmitate|OTHER: [U-13C]-palmitate|PROCEDURE: Biopsy|OTHER: liquid meal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Feasibility of the SmartPrompt for Improving Everyday Function in Dementia
Status: COMPLETED
Conditions: Dementia|Dementia, Vascular|Dementia Alzheimers|Dementia, Mixed|Dementia, Mild|Dementia of Alzheimer Type|Mild Cognitive Impairment|Mild Dementia
Interventions: BEHAVIORAL: SmartPrompt smartphone application
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Preoperative Anxiety and Preemptive Analgesia on Postoperative Delirium in Adenotonsillectomy Surgery
Status: COMPLETED
Conditions: Preoperative Anxiety|Postoperative Delirium
Interventions: OTHER: The Modified Yale Preoperative Anxiety Scale (m-YPAS) of children
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Quantitative Mapping of Substantia Nigra Iron in Parkinson's Disease (Stages I-IV, REM Sleep Behavior Disorder) and Controls
Status: COMPLETED
Conditions: Parkinson Disease|REM Sleep Behavior Disorder|Healthy
Interventions: DRUG: (11C)PE2I|DRUG: Ioflupane
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Robotic Total Hip Arthroplasty Anesthesia Management
Status: NOT_YET_RECRUITING
Conditions: Hip Osteoarthritis|Joint Diseases|Anesthesia
Interventions: PROCEDURE: the robot assisted total hip arthroplasty|PROCEDURE: the conventional total hip arthroplasty
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Nursing Interventions for Clean Intermittent Catheterization Caregivers and Child
Status: UNKNOWN
Conditions: Intermittent Urethral Catheterization|Spinal Dysraphism|Urinary Tract Infections
Interventions: OTHER: experimental group: Training of caregivers|OTHER: Control gruop
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Dupilumab in Japanese Patients With Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: Placebo|DRUG: Dupilumab SAR231893
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of DentalVibe in Reducing Injection Pain and Anxiety During Local Anaesthesia in Children
Status: COMPLETED
Conditions: Pain Management|Local Anaesthesia
Interventions: PROCEDURE: Local anaesthesia with conventional syringe|DEVICE: Local anaesthesia with conventional syringe + Dentalvibe
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lumbopelvic Stabilization Versus Pilates Exercises On Gait Phases And Peak Pressure On Foot In Low Back Pain
Status: UNKNOWN
Conditions: Low Back Pain
Interventions: OTHER: lumbopelvic stabilization exercises|OTHER: pilates exercise|OTHER: conventional therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Treatment With Rituximab on the Progression of Humoral Acute Rejection After Renal Transplantation
Status: COMPLETED
Conditions: Humoral Rejection in Kidney Transplantation
Interventions: DRUG: MabThera|DRUG: Physiological serum : sodium chloride, sodium citrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Dose-Escalation Study of MDX-1100 in Patients With Active Ulcerative Colitis
Status: COMPLETED
Conditions: Ulcerative Colitis
Interventions: DRUG: MDX-1100 (anti-CXCL10 human monoclonal antibody)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Zanubrutinib (BGB-3111) in Combination With Tislelizumab (BGB-A317) in Participants With B-cell Malignancies
Status: COMPLETED
Conditions: Lymphoma|Leukemia
Interventions: DRUG: Zanubrutinib|DRUG: Tislelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EuroPainClinicsStudy X
Status: UNKNOWN
Conditions: Back Pain
Interventions: OTHER: Retrospective observation after 24 months after the spinal procedure|OTHER: Retrospective observation after 12 months after the spinal procedure|OTHER: Prospective evaluation of patients after 12 and 24 months after the spinal procedure
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety of CHF 1535 200/6µg in Not Adequately Controlled Asthmatic Patients
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: CHF1535 200/6 µg|DRUG: BDP 100 µg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Intravenous Cefazolin Plus Oral Probenecid With Oral Cephalexin for the Treatment of Cellulitis
Status: COMPLETED
Conditions: Cellulitis
Interventions: DRUG: IV cefazolin plus oral probenecid and placebo cephalexin|DRUG: Oral cephalexin and saline IV plus probenecid placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Metamucil on Blood Glucose and HbA1c in Type II NIDDM Subjects
Status: TERMINATED
Conditions: Non-Insulin-dependent Diabetes Mellitus
Interventions: DIETARY_SUPPLEMENT: placebo|DIETARY_SUPPLEMENT: 3.4 g psyllium BID|DIETARY_SUPPLEMENT: 6.8g psyllium BID
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of Different Oral Rehydration Solutions
Status: COMPLETED
Conditions: Short Bowel Syndrome
Interventions: DIETARY_SUPPLEMENT: WHO ORS|DIETARY_SUPPLEMENT: Commercial ORS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of the Efficacy of Tidal Volume Breathing and Vital Capacity Breathing During High-flow Nasal Oxygen
Status: NOT_YET_RECRUITING
Conditions: Adult Patients 20 Years of Age or Older Who Are Planning to Undergo Surgery Under General Anesthesia
Interventions: PROCEDURE: Tidal volume breathing technique|PROCEDURE: Vital capacity breathing technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Taking Action: a Care for Type 2 Diabetes Intervention for Couples
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: BEHAVIORAL: Communal Coping Intervention|BEHAVIORAL: Diabetes Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Brief Web-Based Alcohol Reduction Intervention for Undergraduates
Status: COMPLETED
Conditions: Alcohol Use|Heavy Drinking|Negative Consequences of Alcohol Use
Interventions: BEHAVIORAL: THRIVE|BEHAVIORAL: Brief brochure and assessment control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Closed Loop TES for Enhancing Slow Wave Sleep
Status: UNKNOWN
Conditions: Sleep Disturbance|Insomnia
Interventions: DEVICE: Transcranial Electrical Neuromodulation (TES)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Dichoptic Treatment for Amblyopia in Children 8 to 12 Years of Age
Status: NOT_YET_RECRUITING
Conditions: Amblyopia
Interventions: DEVICE: Vivid Vision|DEVICE: Luminopia|DEVICE: Optical Correction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Efficacy and Safety of AZD1981 in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Moderate to Severe COPD
Interventions: DRUG: AZD1981|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Subjects With Metastatic or Locally Advanced Solid Tumors, and Expansion Into Select Solid Tumors (Cervical)
Status: COMPLETED
Conditions: Cervical Cancer
Interventions: DRUG: AGEN1884 + AGEN2034
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of a Compassion Focused Therapy-based Intervention in Detained Youth
Status: COMPLETED
Conditions: Psychopathic Personality Trait|Conduct Disorder|Delinquency
Interventions: BEHAVIORAL: PSYCHOPATHY.COMP program.|OTHER: Treatment As Usual - TAU
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: START: Safety and Anti-Tumor Activity of PeptiCRAd-1 in Treatment of Cancer
Status: RECRUITING
Conditions: Melanoma (Skin)|Triple-Negative Breast Cancer|Non-Small Cell Lung Cancer|Synovial Sarcoma|Myxoid Liposarcoma|Colorectal Cancer
Interventions: DRUG: PeptiCRAd-1|DRUG: Cyclophosphamide|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sanfu Herbal Patch and Sanfu Moxibustion for Persistent Allergic Rhinitis: a Controlled Clinical Trial
Status: UNKNOWN
Conditions: Patch,Chinese Herb|Moxibustion|Allergic Rhinitis
Interventions: DRUG: Sanfu herbal patch|DRUG: Sanfu moxibustion|DRUG: Sanfu herbal patch and moxibustion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Er:YAG Laser Effects on Microbial Population in Conservative Dentistry
Status: COMPLETED
Conditions: Dental Caries|Microbial Colonization
Interventions: DEVICE: Er:YAG Laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ConTempoRary Cardiac Stimulation in Clinical practicE: lEft, BivEntriculAr, Right, and conDuction System Pacing
Status: RECRUITING
Conditions: Arrhythmias, Cardiac|Atrioventricular Block|Reduced Systolic Function|Atrial Fibrillation|Bradyarrhythmia|Ventricular Tachycardia|Ventricular Dysfunction|Ventricular Fibrillation|Ventricular Arrythmia|Atrioventricular Nodal Disease|Atrioventricular Conduction Defects|Atrioventricular Block Complete|Atrioventricular Block Incomplete|Atrioventricular Junctional Rhythm|Bundle-Branch Block|Left Bundle-Branch Block|Heart Failure, Systolic|Block;Atrioventricular|Block; Arrhythmic|Block; Mobitz|Block, Heart|Block, Fascicular|Block Branch Bundle Left|Heart Failure，Congestive|Heart Arrhythmia
Interventions: DEVICE: Cardiac pacing - Conventional RV pacing|DEVICE: Cardiac pacing - Conduction System Pacing|DEVICE: Cardiac pacing - Cardiac resynchronization therapy (pacing - CRTP - or defibrillation - CRTD)|DEVICE: Cardiac pacing - Epicardial pacing|DEVICE: Cardiac pacing - Leadless pacing
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phase I Study of ZD4054 (Zibotentan) and Docetaxel in Patients With Metastatic HRPC
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: ZD4054 (Zibotentan)|DRUG: Docetaxel|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Slump Stretching vs Lumbar Mobilization With Exercises in Relieving Non-radiculating Low Back Pain
Status: UNKNOWN
Conditions: Low Back Pain
Interventions: OTHER: Slump stretching|OTHER: Lumbar mobilization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Hypnosis and Mindfulness on Reducing Pain in Chronic Pain Patients
Status: NOT_YET_RECRUITING
Conditions: Hypnosis, Mindfulness Meditation
Interventions: OTHER: Hypnosis audio|OTHER: Mindfulness meditation audio|OTHER: Natural text audio (control audio)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of LY2062430 in Subjects With Mild-to-Moderate Alzheimer's Disease and in Healthy Volunteers
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: LY2062430|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Combination of Gonadotropin-releasing Hormone Agonist and Human Chorionic Gonadotropin Triggered by Normal Responder in GnRH-antagonist Cycles
Status: UNKNOWN
Conditions: In-vitro Fertilization
Interventions: DRUG: hCG (Ovitrelle 250 mcg mcg - Merck Serono)|DRUG: hCG (Ovitrelle 250 mcg mcg - Merck Serono) + GnRH agonist (Decapeptyl 0.2mg - Ferring Gmgh)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Safety, Tolerability and Efficacy of IONIS-AGT-LRx in Participants With Chronic Heart Failure With Reduced Ejection Fraction
Status: COMPLETED
Conditions: Chronic Heart Failure With Reduced Ejection Fraction
Interventions: DRUG: IONIS-AGT-LRx|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Two Part Trial Investigating the Safety of NN9924 in Healthy Male Subjects
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2|Healthy
Interventions: DRUG: NN9924 (oral)|DRUG: placebo|DRUG: NN9924 (oral)|DRUG: placebo|DRUG: NN9924 (s.c.)|DRUG: NN9924 (i.v.)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Moderate Exercise Training on Vitals and Peak VO2 in Different Age Categories of Adult in COVID-19.
Status: COMPLETED
Conditions: Covid19
Interventions: OTHER: Moderate Exercise Training (Age Group 1; Young adult 17 -30 years)|OTHER: Moderate Exercise Training (Age Group 2; 31 to 45 years)|OTHER: Moderate Exercise Training (Age Group 3; Above 45 years)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Anaesthesia With Propofol Versus Midazolam : Effect on Oxidative Stress in the Brain of Head Trauma Patients
Status: TERMINATED
Conditions: Traumatic Brain Injury
Interventions: DRUG: Propofol|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Use of SOMVC001 (GALA) Vascular Conduit Preservation Solution in Patients Undergoing CABG (STEPS)
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DEVICE: SOMVC001 Vascular Conduit Solution|OTHER: Standard of care Heparin-dosed saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Distance Between Dental Implants as a Risk Indicator for Peri-implant Disease.
Status: RECRUITING
Conditions: Peri-implant Mucositis|Peri-Implantitis
Interventions: DIAGNOSTIC_TEST: Two contiguous dental implants placed with less ≤ 3mm from each other.|DIAGNOSTIC_TEST: Two contiguous dental implants placed with > 3mm from each other.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of HX008 for the Treatment of Patients With Metastatic Triple Negative Breast Cancer
Status: UNKNOWN
Conditions: Triple-negative Breast Cancer
Interventions: DRUG: HX008+Cisplatin+Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Parent Mediated Intervention Program on Children With ASD Exposed to Earthquake in Turkey in February 2023
Status: NOT_YET_RECRUITING
Conditions: Autism Spectrum Disorder|Earthquake|Behavior Problem of Childhood and Adolescence
Interventions: BEHAVIORAL: Online group-based parent-mediated intervention program
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Capecitabine and Streptozocin With or Without Cisplatin in Treating Patients With Unresectable or Metastatic Neuroendocrine Tumors
Status: COMPLETED
Conditions: Gastrointestinal Carcinoid Tumor|Islet Cell Tumor
Interventions: DRUG: capecitabine|DRUG: cisplatin|DRUG: streptozocin|GENETIC: DNA analysis|GENETIC: RNA analysis|GENETIC: protein analysis|GENETIC: proteomic profiling|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Empirical Antibiotic Use in Mild to Moderate Acute Inflammatory Gallbladder Disease
Status: UNKNOWN
Conditions: Cholecystitis, Acute
Interventions: PROCEDURE: Laparoscopic cholecystectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of a Dynamic Upper Limb Orthosis in Patients With Parkinson's Disease
Status: UNKNOWN
Conditions: Parkinson Disease|Tremor, Limb|Rigidity, Muscle
Interventions: OTHER: Dynamic Upper Limb Orthosis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effect of Metformin on Metastatic Breast Cancer as Adjuvant Treatment
Status: COMPLETED
Conditions: Metastatic Breast Cancer
Interventions: DRUG: Metformin plus chemotherapy|DRUG: Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical effecT of Heart Failure Management Via Home Monitoring With a Focus on Atrial Fibrillation (effecT)
Status: TERMINATED
Conditions: Heart Failure (HF)|Atrial Fibrillation
Interventions: DEVICE: Home Monitoring (Cardiac resynchronization therapy and atrial fibrillation therapy, with Home Monitoring feature)|DEVICE: Home Monitoring (Cardiac resynchronization therapy and atrial fibrillation therapy, without Home Monitoring)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Letrozole Pretreatment With Misoprostol Induction of Abortion in First Trimester Missed Abortion
Status: UNKNOWN
Conditions: Missed Abortion
Interventions: DRUG: letrozole|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Does the First Interview Matter: A Comparing Life Stress Interview Versus a Standard Psychiatric Intake Interview for Patients With Functional Somatic Disorder
Status: ACTIVE_NOT_RECRUITING
Conditions: Functional Somatic Disorder|Somatic Symptom Disorder
Interventions: BEHAVIORAL: Life stress interview according to EAET|BEHAVIORAL: Psychiatric interview according to "region stockholm - basutredning"
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Drug-drug Interaction Effect of Itraconazole on the Pharmacokinetics (PK) of AMG 510 in Healthy Participants
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DRUG: AMG 510|DRUG: Itraconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Accelerated Deep TMS in the Elderly Depressed: A Brain Imaging Approach
Status: WITHDRAWN
Conditions: Old Age|Depression
Interventions: DEVICE: accelerated deep rTMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: IN Ketamine Vs IN Midazolam and Fentanyl for Abscess I&D
Status: COMPLETED
Conditions: Abscess|Pain
Interventions: DRUG: intranasal ketamine|DRUG: intranasal fentanyl|DRUG: intranasal midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nicotinamide Riboside (NR) to Treat Moyamoya-like Cerebrovascular Disease in Smooth Muscle Dysfunction Syndrome (SMDS)
Status: RECRUITING
Conditions: Smooth Muscle Dysfunction Syndrome (SMDS)
Interventions: DRUG: Nicotinamide riboside (NR)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gan & Lee Insulin Glargine Target Type (1) Evaluating Research
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: BIOLOGICAL: Gan & Lee Insulin Glargine Injection|BIOLOGICAL: Lantus®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cycloplegic Refraction in Pediatric Patients With Esotropia
Status: RECRUITING
Conditions: Cycloplegia|Refractive Errors|Esotropia|Vision Disorders
Interventions: DRUG: Cyclopentolate|DRUG: Tropicamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Transplantation of Cultured Gut Microflora to Repeat Antibiotic-induced Diarrhea Due to Clostridium Difficile
Status: COMPLETED
Conditions: Clostridium Difficile
Interventions: BIOLOGICAL: Cultured human intestinal microbiota|DRUG: Vancomycin|DRUG: Metronidazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Testing the Addition of an Anti-Cancer Drug, ZEN003694, to the Usual Chemotherapy Treatment (Capecitabine) for Metastatic or Unresectable Cancers
Status: RECRUITING
Conditions: Metastatic Colorectal Carcinoma|Metastatic Malignant Solid Neoplasm|Stage IV Colorectal Cancer AJCC v8|Unresectable Colorectal Carcinoma|Unresectable Malignant Solid Neoplasm
Interventions: DRUG: BET Bromodomain Inhibitor ZEN-3694|PROCEDURE: Biopsy|PROCEDURE: Biospecimen Collection|DRUG: Capecitabine|PROCEDURE: Computed Tomography|PROCEDURE: Magnetic Resonance Imaging|PROCEDURE: Positron Emission Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nitroglycerin Plus Radiotherapy Versus Conventional Radiotherapy in Patients With Lung Cancer.
Status: RECRUITING
Conditions: Non-small Cell Lung Cancer|Brain Metastases|EGFR Gene Mutation
Interventions: COMBINATION_PRODUCT: Nitroglycerin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT