pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Staphylococcus Aureus in Atopic Dermatitis Immunopathology
Status: RECRUITING
Conditions: Atopic Dermatitis
Interventions: OTHER: Blood sample (Day -42 to Day -28, Day 3),Skin swab sampling (Day -42 to Day -28, Day 0, Day 13) , patch test application (Day 0) , skin biopsies (Day 13)|OTHER: Blood sample (Day 0 ,Day 3),Skin swab sampling (Day 0,Day 13), patch test application (Day 1), skin biopsies (Day 13)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Automated Hovering for Congestive Heart Failure Patients: A Pilot Study
Status: COMPLETED
Conditions: Heart Failure
Interventions: BEHAVIORAL: Support partner|BEHAVIORAL: Engagement incentives|BEHAVIORAL: Electronic pill bottle|BEHAVIORAL: Bluetooth scale
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Alpha-lipoic Acid in Diabetic Patients With Ischemic Cardiomyopathy
Status: COMPLETED
Conditions: Ischemic Cardiomyopathy|Diabetes Mellitus
Interventions: DRUG: Alpha Lipoic Acid 600 MG Oral Tablet|OTHER: Placebo Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Learn How Much Rosuvastatin Gets Into the Blood When Taken With or Without Elinzanetant and to Learn About the Safety of Elinzanetant in Healthy Participants
Status: COMPLETED
Conditions: Vasomotor Symptoms as a Sex Hormone-dependent Disorder in Women and Men
Interventions: DRUG: Elinzanetant (BAY3427080)|DRUG: Rosuvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Telotristat Ethyl to Promote Weight Stability in Patients With Advanced Stage Pancreatic Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Locally Advanced Unresectable Pancreatic Adenocarcinoma|Metastatic Pancreatic Adenocarcinoma|Recurrent Pancreatic Adenocarcinoma|Stage III Pancreatic Cancer AJCC v8|Stage IV Pancreatic Cancer AJCC v8
Interventions: DRUG: Gemcitabine|DRUG: Nab-paclitaxel|DRUG: Telotristat Ethyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of Two Identical NN1250 Formulations in Healthy Volunteers
Status: COMPLETED
Conditions: Diabetes|Healthy
Interventions: DRUG: insulin degludec|DRUG: insulin degludec
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Different Iloprost Doses on Symptoms in Systemic Sclerosis
Status: TERMINATED
Conditions: Systemic Sclerosis
Interventions: DRUG: iloprost|DRUG: iloprost low dose|DRUG: iloprost therapy up to 2 ng/kg x min
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bifocal Soft Contact Lenses and Their Effect on Myopia Progression in Children and Adolescents.
Status: COMPLETED
Conditions: Myopia|Esophoria|Fixation Disparity
Interventions: DEVICE: Bifocal Contact Lenses|DEVICE: Placebo Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Long-term Antibody Persistence After a Booster Dose of Menitorix Vaccine
Status: COMPLETED
Conditions: Haemophilus Influenzae Type b|Neisseria Meningitidis|Neisseria Meningitidis-Haemophilus Influenzae Type b Vaccine
Interventions: BIOLOGICAL: Menitorix|BIOLOGICAL: Infanrix IPV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Randomized, Blinded, Placebo-controlled, Phase II Trial of LEE011 in Patients With Relapsed, Refractory, Incurable Teratoma With Recent Progression
Status: COMPLETED
Conditions: Teratoma
Interventions: DRUG: LEE011|DRUG: LEE011 Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effect of Renal Impairment and Dialysis Treatment on the Pharmacokinetics (PK) of a Single Intravenous (IV) TAK-954
Status: COMPLETED
Conditions: Renal Impairment|Healthy Volunteers
Interventions: DRUG: TAK-954
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effect of Dietary Supplemental Fish Oil in Alleviating Health Hazards Associated With Air Pollution
Status: COMPLETED
Conditions: Oxidative Stress|Inflammation|Blood Pressure|Vasoconstriction|Coagulation|Pulmonary Function
Interventions: DIETARY_SUPPLEMENT: Fish oil supplementation|DIETARY_SUPPLEMENT: Sunflower seed oil supplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Autologous Transplantation of Mesenchymal Stem Cells (MSCs) and Scaffold in Full-thickness Articular Cartilage
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: BIOLOGICAL: Bone marrow derived mesenchymal stem cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Carboplatin, Paclitaxel, and Radiation Therapy in Treating Patients With Stage III Non-small Cell Lung Cancer That Cannot Be Removed During Surgery
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DRUG: carboplatin|DRUG: chemotherapy|DRUG: paclitaxel|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: LIBERTY 2: Efficacy & Safety Study of Relugolix in Women With Heavy Menstrual Bleeding Associated With Uterine Fibroids
Status: COMPLETED
Conditions: Heavy Menstrual Bleeding|Uterine Fibroid
Interventions: DRUG: Relugolix|DRUG: Estradiol/norethindrone acetate|DRUG: Relugolix placebo|DRUG: Estradiol/norethindrone acetate placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Percutaneous Immunostimulating Interstitial Laser Thermotherapy in Pancreatic Cancer
Status: TERMINATED
Conditions: Neoplasms Pancreatic
Interventions: DEVICE: imILT|DRUG: Standard chemotherapy treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose Response of Inhaled Tacrolimus in Patients With Moderate Persistent Asthma
Status: COMPLETED
Conditions: Asthma, Bronchial|Bronchial Asthma
Interventions: DRUG: tacrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of Therapeutic Hepatitis B Vaccine
Status: COMPLETED
Conditions: Hepatitis B, Chronic
Interventions: BIOLOGICAL: CVI-HBV-002|BIOLOGICAL: Normal Saline(placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PRP for Treatment of Peyronie's Disease
Status: RECRUITING
Conditions: Peyronie Disease|Sexual Dysfunction, Physiological|Sexual Dysfunction Male|Genital Diseases, Male
Interventions: DRUG: Autologous Platelet Rich Plasma|OTHER: Saline Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Phase II Study of ADT + Abiraterone vs ADT + Docetaxel + Abiraterone
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Cancer
Interventions: DRUG: Docetaxel|DRUG: ADT|DRUG: Abiraterone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exploring Durable Remission With Rituximab in Antineutrophil Cytoplasmic Antibody(ANCA)-Associated Vasculitis
Status: RECRUITING
Conditions: ANCA Associated Vasculitis
Interventions: DRUG: Rituximab|DRUG: endoxan|DRUG: Methylprednisolone|DRUG: Prednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment With Human Umbilical Cord-derived Mesenchymal Stromal Cells in Systemic Sclerosis
Status: RECRUITING
Conditions: Sclerosis, Systemic|Mesenchymal Stem Cells
Interventions: BIOLOGICAL: UCMSC|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Combination of Rosuvastatin and Ezetimibe in Patients With Primary Hypercholesterolemia
Status: COMPLETED
Conditions: Primary Hypercholesterolemia
Interventions: DRUG: HL140 5/10|DRUG: HL140 10/10|DRUG: HL140 20/10|DRUG: Rosuvastatin 5mg → HL140 5/10|DRUG: Rosuvastatin 10mg → HL140 10/10|DRUG: Rosuvastatin 20mg → HL140 20/10
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Effectiveness Trail to Reduce Child Maltreatment, Improve Client Outcomes and Examine Client Burden
Status: COMPLETED
Conditions: Child Maltreatment
Interventions: BEHAVIORAL: SafeCare|BEHAVIORAL: Supportive Case Management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Balloon Sinuplasty In-Office Versus Medical Management for Recurrent Acute Sinusitis Patients (CABERNET)
Status: COMPLETED
Conditions: Recurrent Acute Rhinosinusitis
Interventions: DEVICE: balloon sinus dilation|OTHER: medical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study to Test Different Doses of BI 764532 in Patients With Small Cell Lung Cancer and Other Neuroendocrine Tumours That Are Positive for DLL3
Status: RECRUITING
Conditions: Patients With Small Cell Lung Carcinoma and Other Neoplasms
Interventions: DRUG: BI 764532 - parenteral 1|DRUG: BI 764532 - parenteral 2
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Zanuburutinib in Relapsed and Refractory iMCD: a Prospective, Single-center, Single-arm Trial
Status: RECRUITING
Conditions: Idiopathic Multicentric Castleman's Disease
Interventions: DRUG: Zanubrutinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SLV213 Treatment in Ambulatory COVID-19 Patients
Status: NOT_YET_RECRUITING
Conditions: Covid19
Interventions: DRUG: SLV213|DRUG: SLV213|DRUG: SLV213|DRUG: Placebo|DRUG: Placebo|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Ixazomib With Pegylated IFN-alpha 2b (pIFN) in Metastatic Renal Cell Carcinoma (mRCC)
Status: TERMINATED
Conditions: Metastatic Renal Cell Carcinoma|RCC
Interventions: DRUG: Ixazomib|DRUG: Pegylated IFN-alpha 2b
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Wayfinding Intervention in High-Fidelity Long-Term Memory
Status: COMPLETED
Conditions: Long-Term Memory Decline|Mild Cognitive Impairment
Interventions: DEVICE: LabyrinthVR|DEVICE: Placebo Games|DEVICE: Coherence|DEVICE: Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Kosmos Anatomical Object Labeling and View Identification Pivotal Study
Status: COMPLETED
Conditions: Cardiac Disorder|Hepatic Disorder|Spleen Disorder|Kidney Disorder|Pulmonary Disorder|Renal Disorder|Hepatobiliary Disorders|GYN Disorders
Interventions: DEVICE: Kosmos Anatomical Object Labeling and View Identification Algorithms
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparing Intra Uterine Synechiae Occurence Using Bipolar Energy Compared With Monopolar Energy in Myoma Resection on Women Having Menorraghia and/or Infertility
Status: WITHDRAWN
Conditions: Symptomatic Submucosal Myoma
Interventions: PROCEDURE: Hysteroscopic resection with bipolar energy|PROCEDURE: Hysteroscopic resection with monopolar energy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Safety and Efficacy of 5% Lidocaine Patch and Flurbiprofen Patch for Relieving Acute Low Back Pain
Status: COMPLETED
Conditions: Acute Back Pain
Interventions: DRUG: Lidocaine patch local application|DRUG: Flurbiprofen patch local application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Improved Cognitive Outcomes Associated With Feihe HMO With DHA/ARA in Infant Formula
Status: RECRUITING
Conditions: Cognitive Change
Interventions: DIETARY_SUPPLEMENT: Investigational Formula|DIETARY_SUPPLEMENT: Control Formula|DIETARY_SUPPLEMENT: Breastfeeding
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: tDCS and Emotional Eating
Status: RECRUITING
Conditions: Eating Disorders
Interventions: DEVICE: Transcranial direct current stimulation (brain stimulation)|DEVICE: sham Transcranial direct current stimulation (brain stimulation)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Rehabilitation of Narrative Language in Children With Hearing Impairment and Developmental Language Disorder
Status: COMPLETED
Conditions: Hearing Impaired Children|Developmental Language Disorder
Interventions: BEHAVIORAL: Narrative language intervention program|BEHAVIORAL: Conventional language intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intraperitoneal Carbon Dioxide Concentration Measurement During Standard Laparoscopy With a New Airseal Access Port
Status: WITHDRAWN
Conditions: Laparoscopic Carbon Dioxide Measurement
Interventions: DEVICE: Airseal access port for laparoscopic surgery|DEVICE: Standard Laparoscopy ports
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Little Cigar Oxidants
Status: NOT_YET_RECRUITING
Conditions: Tobacco Use|Oxidative Stress
Interventions: OTHER: High Oxidant Unflavored Little Cigar - Group A|OTHER: Low Oxidant Unflavored Little Cigar - Group B|OTHER: High Oxidant Flavored Little Cigar - Group C|OTHER: Low Oxidant Flavored Little Cigar - Group D|OTHER: Usual Cigarette - Group E|OTHER: Unlit Little Cigar - Group F
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety and Immunogenicity of Three Formulations of Takeda's Tetravalent Dengue Vaccine Candidate (TDV)
Status: COMPLETED
Conditions: Dengue Fever
Interventions: DRUG: TDV Liquid Formulation 1|DRUG: TDV Liquid Formulation 2|DRUG: TDV IDT Lyophilized|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect of Therapeutic Climbing on Muscle Strength, Tone and Balance in Hemiplegic Children
Status: COMPLETED
Conditions: Hemiplegia and Hemiparesis
Interventions: OTHER: Therapeutic Climbing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Learn About the Study Medicine (Called Maplirpacept (PF-07901801)) in Japanese With Hematologic Malignancies
Status: ACTIVE_NOT_RECRUITING
Conditions: Lymphoma|Multiple Myeloma
Interventions: DRUG: maplirpacept (PF-07901801)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Frequency of Polycystic Ovary Syndrome Among Young Reproductive Females Presenting With Hyperandrogenism: a Mixed Cohort Study
Status: RECRUITING
Conditions: PCOS (Polycystic Ovary Syndrome) of Bilateral Ovaries
Interventions: DIAGNOSTIC_TEST: clinical, biophysical and biochemical assessment of young females with clinical hyperandrogenism
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Testing an Arts-based Program to Reduce Nurse Stigma Towards Perinatal Substance Use
Status: ENROLLING_BY_INVITATION
Conditions: Nurse's Role|Stigma, Social|Implicit Bias
Interventions: OTHER: ArtSpective
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Time-motion-mode Ultrasound Diaphragm Measures in Patients With Acute Respiratory Distress in Emergency Department
Status: COMPLETED
Conditions: Respiratory Distress Syndrome, Adult
Interventions: DEVICE: Vivid S6 GE Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Switching From Fondaparinux to Bivalirudin or Unfractionated Heparin in ACS Patients Undergoing PCI
Status: COMPLETED
Conditions: Acute Coronary Syndromes
Interventions: DRUG: Switching from Fondaparinux to Bivalirudin or Unfractionated Heparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Short-term, Intensive Psychodynamic Group Therapy Versus Cognitive-behavioral Group Therapy in the Day Treatment
Status: UNKNOWN
Conditions: Anxiety Disorders|Depressive Disorders|Personality Disorders
Interventions: BEHAVIORAL: Intensive Group Analytic Psychotherapy|BEHAVIORAL: Intensive transdiagnostic cognitive-behavioral group therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective Trial Comparing Two Different Polypropylene Meshes for Inguinal Hernias
Status: COMPLETED
Conditions: Hernia, Inguinal
Interventions: DEVICE: ULTRAPRO Mesh|DEVICE: 3DMAX|OTHER: Evaluation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Budesonide on Incidence of ≥ Gr2 Diarrhea in Multiple Myeloma (MM) Patients Undergoing Autologous Stem Cell Transplant
Status: RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: Budesonide EC|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Compare Marginal Bone Loss Around Implants From Two Dental Implant Systems.
Status: COMPLETED
Conditions: Jaw, Edentulous, Partially
Interventions: DEVICE: ASTRA TECH Implant System; Fixture ST: Ø 4.5 cm in lengths of 9, 11 and 13 mm.|DEVICE: 3i Osseotite® implant: Ø 4.0 in lengths of 8.5, 10, 11.5 and 13 mm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Using Radiation Therapy and Temozolomide to Treat Glioblastoma in Patients Over 70
Status: RECRUITING
Conditions: Glioblastoma
Interventions: RADIATION: Hypofractionated radiotherapy|DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Midazolam and Dexmedetomidine on Heart Function - A Randomized MRI-based Study.
Status: COMPLETED
Conditions: Cardiac Function|Sedation|Magnetic Resonance Imaging
Interventions: DRUG: Midazolam|DRUG: Dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Inpatient Consultation for High-Risk Chronically Ill Children Receiving Care in an Enhanced Medical Home
Status: COMPLETED
Conditions: Chronic Illnesses
Interventions: OTHER: Comprehensive Care with Inpatient consultation|OTHER: Usual Inpatient Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Serum Markers sFLt1 and PlGF for the Prediction of the Complications of the Placental Vascular Pathologies in the 3rd Quarter of the Pregnancy.
Status: COMPLETED
Conditions: Pre-Eclampsia|HELLP Syndrome|Fetal Death|Eclampsia|Placental Abruption|Fetal Growth Retardation, Antenatal
Interventions: DIAGNOSTIC_TEST: sampling of the serum marker sFlt1 and PlGF
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of the Efficacy, Safety and Tolerability of CNTO 1959, a Human Anti-IL 23 Monoclonal Antibody in Participants With Palmoplantar Pustulosis
Status: COMPLETED
Conditions: Palmoplantaris Pustulosis
Interventions: DRUG: Placebo|DRUG: CNTO 1959
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Two Methods of Jejunal Placement of Enteral Feeding Tubes in Critically Ill Patients
Status: COMPLETED
Conditions: Critically Ill
Interventions: PROCEDURE: Jejunal tube placement using the unguided frictional method|PROCEDURE: Jejunal tube placement using the endoscopic method
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Irrisept Versus Standard of Care in the Prevention of Surgical Site Infections
Status: TERMINATED
Conditions: Surgical Site Infection
Interventions: DEVICE: IrriSept System|OTHER: No Intervention - Standard of Care (SoC) only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Ipsilateral and Contralateral Index for the Interpretation of Adrenal Vein Sampling (AVS) in Primary Aldosteronism
Status: COMPLETED
Conditions: Primary Aldosteronism|Primary Aldosteronism Due to Aldosterone Producing Adenoma|Primary Aldosteronism Due to Adrenal Hyperplasia (Bilateral)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Dorsal Penile Nerve Block for Rigid Cystoscopy in Men
Status: COMPLETED
Conditions: Pain
Interventions: PROCEDURE: Dorsal Penile Nerve Block|DRUG: Ropivacaine|DRUG: Tetracaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Alpelisib Plus Olaparib in Platinum-resistant/Refractory, High-grade Serous Ovarian Cancer, With no Germline BRCA Mutation Detected
Status: ACTIVE_NOT_RECRUITING
Conditions: Ovarian Cancer
Interventions: DRUG: Alpelisib|DRUG: Olaparib|DRUG: Paclitaxel|DRUG: Pegylated liposomal doxorubicin (PLD)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Pre-Operative Transversus Abdominis Plane (TAP) Block in the Post Operative Opioid Consumption in Morbid Obese Patients Undergoing Laparoscopic Gastric Bypass Surgery: A Prospective,Randomized, Blinded Study
Status: COMPLETED
Conditions: Pain|Obesity|Surgery
Interventions: DRUG: Placebo|DRUG: (study group) will receive a bilateral TAP block using 20 cc of 0.5% ropivacaine on each side.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Nal-IRI With 5-fluorouracil (5-FU) and Leucovorin or Gemcitabine Plus Cisplatin in Advanced Biliary-tract Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Adenocarcinoma Metastatic|Biliary Tract Cancer|Adenocarcinoma of the Biliary Tract|Adenocarinoma Locally Advanced|Non-Resectable Hepatocellular Carcinoma|Intrahepatic Bile Duct Carcinoma|Extrahepatic Bile Duct Carcinoma
Interventions: DRUG: Arm NaI-IRI + 5-FU + Leucovorin (Arm A)|DRUG: Arm Cisplatin + Gemcitabine (Arm B)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pre- and Postoperative Use of ZD1839 (Iressa) in Recurrent Glioblastoma, Including Translational Research
Status: COMPLETED
Conditions: Recurrent Glioblastoma
Interventions: DRUG: Gefitnib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Evaluate the Pharmacokinetic of Diacerein and Rhein After Maximum Use in Patients With Epidermolysis Bullosa (EB)
Status: COMPLETED
Conditions: Epidermolysis Bullosa (EB)|Epidermolysis Bullosa Simplex|Dystrophic Epidermolysis Bullosa|Junctional Epidermolysis Bullosa
Interventions: DRUG: Diacerein 1% Ointment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Comparative Performance of PureVision Lens Designs
Status: COMPLETED
Conditions: Myopia
Interventions: DEVICE: Currently Marketed PureVision Contact Lens.|DEVICE: Alternate Design of the PureVision Contact Lens.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: PROACTIVE: Surgical Resection Outcomes in Locally Advanced and Unresectable Pancreatic Cancer After Neoadjuvant Chemotherapy
Status: RECRUITING
Conditions: Locally Advanced Pancreatic Adenocarcinoma|Stage III Pancreatic Cancer American Joint Committee on Cancer v8|Unresectable Pancreatic Adenocarcinoma
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|PROCEDURE: Distal Pancreatectomy|PROCEDURE: Laparoscopy|PROCEDURE: Magnetic Resonance Imaging|PROCEDURE: Pancreaticoduodenectomy|OTHER: Questionnaire Administration|PROCEDURE: Surgical Procedure|PROCEDURE: Total Pancreatectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Jing Si Herbal Tea on Inflammation in Patients With Cardiovascular Disease
Status: NOT_YET_RECRUITING
Conditions: Inflammatory Response|Gut Microbiome|Life Quality|Trimethylamine N-oxide|Cardiovascular Diseases|Herbal Medicine
Interventions: DIETARY_SUPPLEMENT: Jing Si herbal tea liquid packet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Longitudinal 2-year Bone Marrow Study of Eltrombopag in Previously Treated Adults, With Chronic Immune (Idiopathic) Thrombocytopenic Purpura (ITP)
Status: COMPLETED
Conditions: Purpura, Thrombocytopaenic, Idiopathic
Interventions: DRUG: Eltrombopag olamine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Knee Osteotomy Associated With Allograft Meniscus Transplantation
Status: RECRUITING
Conditions: Malalignment, Bone|Osteoarthritis, Knee
Interventions: PROCEDURE: Knee osteotomy associated with meniscal allograft transplantation|PROCEDURE: Knee osteotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Single Ascending Doses of GGF2 in Patients With Left Ventricular Dysfunction and Symptomatic Heart Failure
Status: COMPLETED
Conditions: Heart Failure
Interventions: DRUG: Glial growth factor 2/ Neuregulin 1β3|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Symbiotics and Systemic Inflammation in Chronic Kidney Disease
Status: UNKNOWN
Conditions: Chronic Renal Failure|Diabete Type 2|Systemic Inflammation
Interventions: BIOLOGICAL: probiotic Vivomixx®|BIOLOGICAL: prebiotic Orafti®Synergy1|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Photodynamic Therapy on Soft Tissue Healing After Tooth Extraction at Sites of Periodontal Infection
Status: RECRUITING
Conditions: Periodontitis
Interventions: DRUG: Dental diode laser device Paiwei™（Zhengzhou Gata biotechnology Co.,Ltd.,China） which was 650-670nm with a power of 160mw-220mw.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Basal Bolus Insulin Versus SSRI in Type 2 Diabetes Undergoing General Surgery
Status: COMPLETED
Conditions: Type 2 Diabetes|Inpatient Hyperglycemia
Interventions: DRUG: Insulin glargine|DRUG: Regular insulin|DRUG: Insulin glulisine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An RCT of Mycophenolate Mofetil (MMF) in Fibrotic Hypersensitivity Pneumonitis
Status: RECRUITING
Conditions: Hypersensitivity Pneumonitis
Interventions: DRUG: Mycophenolate Mofetil plus prednisolone|DRUG: Prednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Surgical Interventions for Lateral Epicondylitis: A Prospective Study
Status: UNKNOWN
Conditions: Lateral Epicondylitis|Tennis Elbow
Interventions: PROCEDURE: Arthroscopic tenotomy|PROCEDURE: Open tenotomy|PROCEDURE: Debridement and repair
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Intratumoral IVX037 in Patients With Advanced or Metastatic Solid Tumours
Status: RECRUITING
Conditions: Colorectal Cancer|Gastric Cancer|Ovarian Cancer
Interventions: BIOLOGICAL: IVX037|BIOLOGICAL: Sintilimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Alpha-1-Antitrypsin (AAT) To Treat Emphysema In AAT-Deficient Patients (EXACTLE)
Status: COMPLETED
Conditions: Alpha 1-Antitrypsin Deficiency
Interventions: DRUG: Alpha1-Proteinase Inhibitor (Human)|DRUG: Albumin (Human) 20%, United States Pharmacopeia (USP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Innovative Trial Assessing Donor Sex on Recipient Mortality
Status: UNKNOWN
Conditions: Red Blood Cell Transfusion
Interventions: OTHER: RBC Transfusion from male donor|OTHER: RBC Transfusion from female donor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Closed Loop Propofol Administration in Pediatric Cardiac Surgery
Status: COMPLETED
Conditions: Pediatric Cardiac Surgery|Intraoperative Awareness|Automated Drug Delivery
Interventions: OTHER: IAADS|OTHER: Manual propofol administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: Clinical Study of Lewis Antigen Assay Combined With CA19-9 Assay to Assess Prognosis in Patients With Pancreatic Cancer
Status: RECRUITING
Conditions: PDAC
Interventions: DIAGNOSTIC_TEST: Lewis genotype detection reagent
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Ask Advise Connect (AAC) Harris Heath CPRIT
Status: ACTIVE_NOT_RECRUITING
Conditions: Tobacco Use Cessation
Interventions: BEHAVIORAL: Quitline-Delivered Proactive Telephone Counseling|BEHAVIORAL: Follow-Up Phone Call|BEHAVIORAL: Smoking Cessation Training|BEHAVIORAL: Qualitative Interviews Concerning the Implementation of AAC
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Dihydrocapsiate on Adaptive and Diet-Induced Thermogenesis With a High Protein Very Low Calorie Diet
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: dihydrocapsiate capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of TAK-625 for the Treatment of Progressive Familial Intrahepatic Cholestasis (PFIC)
Status: ACTIVE_NOT_RECRUITING
Conditions: Progressive Familial Intrahepatic Cholestasis (PFIC)
Interventions: DRUG: TAK-625
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety of Spinal Anesthesia in Patients With Tibial Shaft Fracture
Status: UNKNOWN
Conditions: Tibial Fracture
Interventions: PROCEDURE: General anesthesia|PROCEDURE: Spinal anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Randomized, Placebo and Ciclosporin Controlled Study of ISA247 in Plaque Psoriasis Patients
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: voclosporin|DRUG: Ciclosporin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Aerobic and Resistance Training in Patients With Type 2 Diabetes on Vitamin D
Status: NOT_YET_RECRUITING
Conditions: Diabetes Mellitus, Type 2
Interventions: OTHER: Resistance training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: CLArithromycin Versus AZIthromycin in the Treatment of Mycobacterium Avium Complex (MAC) Lung Infections
Status: RECRUITING
Conditions: Lung Infection|Mycobacterium Avium Complex
Interventions: DRUG: Clarithromycin 1000 MG|DRUG: Azithromycin 250 mg|DRUG: Rifampicin|DRUG: Ethambutol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Supratotal Resection for Gliomas Within Noneloquent Areas
Status: UNKNOWN
Conditions: Glioma
Interventions: PROCEDURE: total resection|PROCEDURE: supratotal resection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Value of Addition of Human Menopausal Gonadotropin Drug Following Oocytes Retrieval in IVF Cycles
Status: RECRUITING
Conditions: Infertility
Interventions: DRUG: human menopausal gonadotropin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gemcitabine With or Without Pazopanib in Treating Patients With Refractory Soft Tissue Sarcoma
Status: COMPLETED
Conditions: Adult Alveolar Soft Part Sarcoma|Adult Angiosarcoma|Adult Desmoplastic Small Round Cell Tumor|Adult Epithelioid Hemangioendothelioma|Adult Epithelioid Sarcoma|Adult Extraskeletal Myxoid Chondrosarcoma|Adult Extraskeletal Osteosarcoma|Adult Fibrosarcoma|Adult Leiomyosarcoma|Adult Liposarcoma|Adult Malignant Peripheral Nerve Sheath Tumor|Adult Rhabdomyosarcoma|Adult Synovial Sarcoma|Adult Undifferentiated Pleomorphic Sarcoma|Malignant Adult Hemangiopericytoma|Recurrent Adult Soft Tissue Sarcoma|Sarcoma|Stage III Adult Soft Tissue Sarcoma AJCC v7|Stage IV Adult Soft Tissue Sarcoma AJCC v7
Interventions: DRUG: Gemcitabine|DRUG: Gemcitabine Hydrochloride|OTHER: Laboratory Biomarker Analysis|DRUG: Pazopanib|DRUG: Pazopanib Hydrochloride|OTHER: Placebo Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Systematized Quality Exercise Alternatives for Stress Incontinence
Status: COMPLETED
Conditions: Stress Urinary Incontinence|Pelvic Floor; Weak|Incontinence, Urinary|Quality of Life
Interventions: BEHAVIORAL: Pelvic Floor Physical Therapy|DEVICE: Home Biofeedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Procalcitonin Guided Antibiotic Therapy and Hospitalisation in Patients With Lower Respiratory Tract Infections: The "ProHOSP" Study
Status: COMPLETED
Conditions: Lower Respiratory Tract Infection|Pneumonia|Bronchitis
Interventions: BEHAVIORAL: a strategy based on PCT guided AB therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Cholesterol Absorption Inhibition Study
Status: COMPLETED
Conditions: Cholesterol Absorption Inhibition
Interventions: DIETARY_SUPPLEMENT: Reference spread|DIETARY_SUPPLEMENT: Placebo spread|DIETARY_SUPPLEMENT: Test spread
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Clinical Evaluation of the Antidepressant Effect of the Use of Probiotics in Bipolar Disorder
Status: RECRUITING
Conditions: Bipolar Disorder
Interventions: OTHER: Probiotic Group|OTHER: Placebo Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Autologous Platelets Concentrate and Autologous Thrombin for the Treatment of Deep Burn Trauma
Status: COMPLETED
Conditions: Burns
Interventions: PROCEDURE: DE graft and PRP concentrate|PROCEDURE: DE graft
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of PCI-32765 (Ibrutinib) Versus Rituximab in Relapsed or Refractory Chronic Leukemia/Lymphoma
Status: COMPLETED
Conditions: Chronic Lymphocytic Leukemia|Small Lymphocytic Lymphoma
Interventions: DRUG: Rituximab|DRUG: Ibrutinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of P276-00 in Combination With Gemcitabine in Patients With Advanced Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DRUG: P276-00|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transcranial Direct Current Stimulation Augmented Exposure and Response Prevention for Obsessive-Compulsive Disorder
Status: COMPLETED
Conditions: Obsessive-Compulsive Disorder
Interventions: OTHER: ERP plus tDCS|OTHER: ERP plus sham tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of CSL222 (Etranacogene Dezaparvovec) Gene Therapy in Adults With Hemophilia B With Pretreatment Adeno-associated Virus Serotype 5 (AAV5) Neutralizing Antibodies (Nabs)
Status: RECRUITING
Conditions: Hemophilia B
Interventions: GENETIC: CSL222 (AAV5-hFIXco-Padua)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Role of Induction Gemcitabine and Cisplatin in Locoregionally Advanced Nasopharyngeal Carcinoma in the Era of IMRT
Status: ACTIVE_NOT_RECRUITING
Conditions: Nasopharyngeal Carcinoma
Interventions: DRUG: Gemcitabine|DRUG: cisplatin|DRUG: cisplatin|RADIATION: Intensity-modulated Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pooled Mutant KRAS-Targeted Long Peptide Vaccine Combined With Nivolumab and Ipilimumab for Patients With Resected Mismatch Repair Protein (MMR-p) Colorectal and Pancreatic Cancer
Status: RECRUITING
Conditions: Colorectal Cancer|Pancreatic Cancer
Interventions: DRUG: KRAS peptide vaccine|DRUG: Nivolumab|DRUG: Ipilimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Carbohydrate Loading and Elderly Patients Undergoing Spine Surgery
Status: RECRUITING
Conditions: Diet, Carbohydrate Loading
Interventions: DIETARY_SUPPLEMENT: Gatorade Thirst Quencher
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Diode Laser Activated Irrigation Versus Ultrasonic on Post-Operative Pain in Single Visit of Necrotic Teeth
Status: UNKNOWN
Conditions: Necrosis
Interventions: OTHER: diode laser activated irrigation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Cognitive Training Tool Based on Life-logging in Mild Cognitive Impairment (ReMemory-MCI)
Status: UNKNOWN
Conditions: Mild Cognitive Impairment
Interventions: BEHAVIORAL: ReMemory-MCI training|BEHAVIORAL: Control intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Aducanumab in Participants With Mild Cognitive Impairment Due to Alzheimer's Disease or With Mild Alzheimer's Disease Dementia to Evaluate the Safety of Continued Dosing in Participants With Asymptomatic Amyloid-Related Imaging Abnormalities
Status: TERMINATED
Conditions: Cognitive Dysfunction|Alzheimer's Disease
Interventions: DRUG: Aducanumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Nab-Paclitaxel and S-1 in Resectable Pancreatic Cancer
Status: UNKNOWN
Conditions: Pancreatic Neoplasms
Interventions: DRUG: Nab paclitaxel and S-1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RC48 Plus Tislelizumab, Low-dose Capecitabine and Celecoxib for HER2-positive Metastatic Colorectal Cancer
Status: RECRUITING
Conditions: Colorectal Cancer
Interventions: DRUG: Anti-HER2 ADC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prophylactic Oral Antibiotics on Sinonasal Outcomes Following Endoscopic Transsphenoidal Surgery for Pituitary Lesions
Status: RECRUITING
Conditions: Antibiotics|Pituitary Adenoma
Interventions: DRUG: Placebo|DRUG: Oral Antibiotics cefdinir or trimethoprim/sulfamethoxazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ketamine Frequency Treatment for Major Depressive Disorder
Status: WITHDRAWN
Conditions: Treatment Resistant Depression
Interventions: DRUG: Ketamine|DRUG: Ketamine/Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A FIRST IN HUMAN TO EVALUATE THE SAFETY AND IMMUNOGENICITY OF SARS-CoV-2 UQSC2 VACCINE IN HEALTHY ADULTS.
Status: COMPLETED
Conditions: COVID-19
Interventions: BIOLOGICAL: UQSC2 Vaccine|BIOLOGICAL: NVX-CoV2373 vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of EDP-938 in Hematopoietic Cell Transplant Recipients Infected With Respiratory Syncytial Virus of the Upper Respiratory Tract
Status: TERMINATED
Conditions: Respiratory Syncytial Virus Infections
Interventions: DRUG: EDP-938|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: MindOb: A 12-month Computerized Mindfulness-based Intervention for Obese Individuals
Status: UNKNOWN
Conditions: Obesity|Binge-Eating Disorder
Interventions: BEHAVIORAL: Mindfulness-based intervention|BEHAVIORAL: Sham meditation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of BRACE Protocol on Fall Risk Among Elderly Population
Status: COMPLETED
Conditions: Fall Patients
Interventions: OTHER: Balance Resistance Aerobic Cognitive exercises (BRACE)|OTHER: Otago's Protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Efficacy, Safety and Tolerability of Low Molecular Weight Heparin vs. Unfractionated Heparin in Stroke
Status: UNKNOWN
Conditions: Embolic Stroke
Interventions: DRUG: Enoxaparin|DRUG: Heparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: GX-I7 With Cyclophosphamide in Patients With Metastatic or Recurrent Solid Tumors
Status: COMPLETED
Conditions: Solid Tumor
Interventions: DRUG: GX-I7|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT