pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Slow and Accelerated Rehabilitation Protocols
Status: UNKNOWN
Conditions: Rotator Cuff Injuries|Rotator Cuff Tears|Pain, Shoulder
Interventions: OTHER: Accelerated (ACCEL) protocol group|OTHER: Slow (SLOW) protocol group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Venetoclax, Ibrutinib, Prednisone, Obinutuzumab, and Revlimid (ViPOR) in Relapsed/Refractory B-cell Lymphoma
Status: RECRUITING
Conditions: Lymphoma|Non-Hodgkin Lymphoma|Diffuse Large B-Cell Lymphoma|Burkitt Lymphoma
Interventions: DRUG: Venetoclax|DRUG: Ibrutinib|DRUG: Prednisone|BIOLOGICAL: Obinutuzumab|DRUG: Revlimid (lenalidomide)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Recombinant Human Prolactin for Lactation Induction
Status: COMPLETED
Conditions: Lactation
Interventions: DRUG: Recombinant Human Prolactin|BIOLOGICAL: Recombinant human prolactin|BIOLOGICAL: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Lipoic Acid and Prevention of Heart Disease
Status: UNKNOWN
Conditions: Atherosclerosis
Interventions: DIETARY_SUPPLEMENT: R-alpha lipoic acid|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Immunogenicity of Clade C ALVAC and gp120 HIV Vaccine
Status: COMPLETED
Conditions: HIV Infections
Interventions: BIOLOGICAL: ALVAC-HIV (vCP2438)|BIOLOGICAL: Bivalent Subtype C gp120/MF59|BIOLOGICAL: Bivalent Subtype C gp120 admixed with Al(OH)3 Suspension|BIOLOGICAL: Bivalent Subtype C gp120
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Post-thrombectomy Intra-arterial Tenecteplase for Acute manaGement of Non-retrievable Thrombus and No-reflow in Emergent Stroke
Status: NOT_YET_RECRUITING
Conditions: Ischemic Stroke, Acute|Cerebrovascular Disorders|Brain Disorder|Central Nervous System Diseases
Interventions: DRUG: Intra-arterial tenecteplase injection at the completion of thrombectomy|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Monitoring SOF/VEL in Treatment Naïve, HCV Participants With Active Infection
Status: COMPLETED
Conditions: Hepatitis C|HIV-1-infection|Liver Diseases
Interventions: DRUG: Sofosbuvir/Velpatasvir (SOF/VEL)|OTHER: Minimal Monitoring (MINMON) Strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Abiraterone With Different Steroid Regimens for Side Effect Related to Mineralcorticoid Excess Prevention in Prostate Cancer Prior to Chemotherapy
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: Abiraterone Acetate|DRUG: Prednisone 5 mg twice daily|DRUG: Prednisone 5 mg once daily|DRUG: Prednisone 2.5 mg twice daily|DRUG: Dexamethasone 0.5 mg once daily
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: D-Ribose for Fatigue in Subjects With Fibromyalgia
Status: COMPLETED
Conditions: Fibromyalgia
Interventions: DRUG: D-Ribose Powder|DIETARY_SUPPLEMENT: Placebo Powder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Aprepitant in the Prevention of Cisplatin-induced Delayed Emesis
Status: TERMINATED
Conditions: Emesis
Interventions: DRUG: aprepitant + dexamethasone|DRUG: metoclopramide + dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Vaccine Therapy in Treating Patients With Advanced or Recurrent Cancer
Status: COMPLETED
Conditions: Anal Cancer|Cervical Cancer|Esophageal Cancer|Head and Neck Cancer|Penile Cancer|Vulvar Cancer
Interventions: BIOLOGICAL: human papillomavirus 16 E7 peptide|BIOLOGICAL: synthetic human papillomavirus 16 E6 peptide
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: DS-8201a in Human Epidermal Growth Factor Receptor 2 (HER2)-Expressing or -Mutated Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: Trastuzumab deruxtecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Accommodation Response in Hypermetropic Anisometropia (ARIHA Study)
Status: RECRUITING
Conditions: Anisometropic Amblyopia|Accommodation Disorder
Interventions: OTHER: Bespoke glasses prescription worn during amblyopia treatment.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preeclampsia Risk Assessment: Evaluation of Cut-offs to Improve Stratification
Status: COMPLETED
Conditions: Preeclampsia and Eclampsia|Preeclampsia Severe|Gestational Hypertension|Chronic Hypertension in Obstetric Context|Superimposed Pre-Eclampsia|Preeclampsia Mild
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of the Effect of Multiple Doses of Rifampin on the Single Dose Pharmacokinetics of RO5424802
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: RO5424802|DRUG: rifampin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Efficacy, Safety and Tolerability Study of Chloroprocaine 3% Gel Eye Drops in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Ocular gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study on Efficacy of iv PCA With Fentanyl or Sufentanil in Patients Undergoing Laparoscopic Nephrectomy
Status: COMPLETED
Conditions: Patients Undergoing Laparoscopic Nephrectomy
Interventions: DRUG: Sufentanil group|DRUG: Fentanyl group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Vonoprazan Hp Dual or Triple Eradication Regimes
Status: RECRUITING
Conditions: Helicobacter Pylori
Interventions: DRUG: Vonoprazan Fumarate+Amoxycillin+Clarithromycin 14days (VAC14)|DRUG: Vonoprazan Fumarate+Amoxycillin 14days (VA14)|DRUG: Vonoprazan Fumarate+Amoxycillin 7days (VA7)|DRUG: Vonoprazan Fumarate+Tetracycline+Furazolidone 14days (VTF14)|DRUG: Vonoprazan Fumarate+Tetracycline+Furazolidone 7days (VTF7)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Uptake and Utility of Clinical Pathways for Newly Diagnosed Patients With Multiple Myeloma
Status: RECRUITING
Conditions: Multiple Myeloma|Multiple Myeloma Without Mention of Remission
Interventions: OTHER: Multiple Myeloma Pathway|OTHER: All4Cure Platform|OTHER: Documentation Pathway
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A New Therapeutic Approach for Root Coverage
Status: COMPLETED
Conditions: Gingival Recession
Interventions: PROCEDURE: Newly forming bone technique for root coverage|OTHER: Subepithelial connective tissue graft for root coverage.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy & Safety of an Intra-Articular Ampion Injection for Pain of Osteoarthritis of the Knee
Status: COMPLETED
Conditions: Osteoarthritis of the Knee
Interventions: BIOLOGICAL: 4 mL injection of AMPION™|DRUG: 4 mL injection of Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: ACTolog in Patients With Solid Cancers
Status: COMPLETED
Conditions: Cancer|Solid Tumor
Interventions: DRUG: Fludarabine|DRUG: Cyclophosphamide|BIOLOGICAL: IMA101 product|BIOLOGICAL: Recombinant human interleukin-2|DIAGNOSTIC_TEST: IMADetect|DRUG: Atezolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pregnancy Complications in Women With BMI>25 kg/m2 Enrolled in a Healthy Lifestyle and Eating Habits Program
Status: UNKNOWN
Conditions: Maternal Obesity Complicating Pregnancy, Birth,or Puerperium|Gestational Diabetes Mellitus in Pregnancy, Diet- Controlled|Exercise Addiction|High-Risk Pregnancy|Dietary Modification
Interventions: BEHAVIORAL: Specific Therapeutic Lifestyle Changes program in pregnancy|BEHAVIORAL: Dietary and behavioral counselling in pregnancy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety & Tolerability of Berinert® (C1 Inhibitor) Therapy to Prevent Rejection
Status: COMPLETED
Conditions: Kidney Transplantation
Interventions: DRUG: C1 Esterase Inhibitor|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Resiliency Training in Adolescents With NF1 and NF2
Status: UNKNOWN
Conditions: Neurofibromatoses
Interventions: BEHAVIORAL: Stress and Symptom Management Program 1|BEHAVIORAL: Stress and Symptom Management Program 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Clinical Efficacy of Platelet Gel From Cord Blood for the Treatment of Diabetic Foot Ulcers
Status: COMPLETED
Conditions: Diabetic Foot Ulcers
Interventions: BIOLOGICAL: Allogeneic cord blood platelet gel-CBPG|OTHER: Standard Local Medications-SLM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Cawthorne Cooksey Exercises on Balance in Children With Hearing Deficits
Status: COMPLETED
Conditions: Hearing Disorders
Interventions: OTHER: Cawthorne Cooksey Exercises for Balance Training|OTHER: Swiss Ball Exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Open-label, Multicenter, Multiple Dose, Phase 1 Study to Establish the Maximum Tolerated Dose of E7389 Liposomal Formulation in Patients With Solid Tumors
Status: COMPLETED
Conditions: Solid Tumors
Interventions: DRUG: Eribulin-LF
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing the Acceptability of Pentasa® Sachets Versus Pentasa® Tablets in Children With Crohn´s Disease
Status: COMPLETED
Conditions: Crohn's Disease
Interventions: DRUG: Crohn's Disease
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE|Primary Purpose: PREVENTION
Clinical trial: Lowering-hyperuricemia Treatment on Cardiovascular Outcomes in Peritoneal Dialysis Patients
Status: UNKNOWN
Conditions: Hyperuricemia
Interventions: DRUG: Febuxostat|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Four-Week Study to Measure the Effectiveness of an Experimental Mouthwash Used After Teeth Cleaning
Status: COMPLETED
Conditions: Dental Plaque
Interventions: DEVICE: 19416-154-1|DEVICE: W002194-0221P
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Supraspinal Control of Lower Urinary Tract Function in Healthy Controls and Patients With Bladder Dysfunction
Status: COMPLETED
Conditions: Neurogenic Lower Urinary Tract Dysfunction|Multiple Sclerosis|Overactive Bladder|Spinal Cord Injury
Interventions: OTHER: fMRI|OTHER: bladder filling|OTHER: bladder cooling|OTHER: additional post-treatment fMRI scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Genotype-tailored Treatment of Symptomatic Acid-Reflux in Children With Uncontrolled Asthma
Status: COMPLETED
Conditions: Asthma|Gastroesophageal Reflux
Interventions: DRUG: commercially available lansoprazole|DRUG: matched placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Nicotinic Acid Composition of HDL and Arterial Endothelium Function in Premature Coronary Heart Disease and High HDL
Status: TERMINATED
Conditions: Dyslipidemias
Interventions: DRUG: Nicotinic acid|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Ablation Targets of Scar-related Ventricular Tachycardia Identified by Dynamic Functional Substrate Mapping
Status: COMPLETED
Conditions: Tachycardia, Ventricular
Interventions: PROCEDURE: Radiofrequency ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparison of 122-0551 Foam Versus Vehicle Foam in Subjects With Plaque Psoriasis (Study 306)
Status: COMPLETED
Conditions: Plaque Psoriasis
Interventions: DRUG: 122-0551 Foam|DRUG: Vehicle Foam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Prothromplex Total (Prothrombin Complex Concentrate) in Oral Anticoagulant Reversal
Status: COMPLETED
Conditions: Prothrombin Complex Factor Deficiency
Interventions: BIOLOGICAL: Prothrombin complex concentrate (coagulation factors IX, II, VII and X in combination)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectıveness of Foot Core Exercises on paın and functıonal Performance ın patıents wıth Patellofemoral paın Syndrome
Status: RECRUITING
Conditions: Patellofemoral Pain Syndrome
Interventions: OTHER: Foot core exercises|OTHER: Conventional Physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Transcranial Direct Current Stimulation in a Smoking Cessation Trial
Status: WITHDRAWN
Conditions: Nicotine Dependence
Interventions: DEVICE: active transcranial Direct Current Stimulation|DEVICE: sham transcranial Direct Current Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: TELESTAR (Telotristat Etiprate for Somatostatin Analogue Not Adequately Controlled Carcinoid Syndrome)
Status: COMPLETED
Conditions: Carcinoid Syndrome
Interventions: DRUG: Telotristat etiprate|DRUG: Placebo-matching telotristat etiprate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Precision Medicine for Liver Tumours With Quantitative Magnetic Resonance Imaging and Whole Genome Sequencing
Status: ACTIVE_NOT_RECRUITING
Conditions: Liver Cancer|Liver Metastasis Colon Cancer
Interventions: GENETIC: utility of whole genome sequencing (WGS) to aid clinical decision making in patients referred for liver resection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Applicability of a Cellular Resolution Full-field OCT Image System for Pigmented and Non-pigmented Skin Tumors
Status: RECRUITING
Conditions: Skin Lesion|Skin Cancer
Interventions: DEVICE: Cellular resolution full-field optical coherence tomography|DEVICE: Confocal microscopy|DEVICE: Optical coherence tomography imaging|DEVICE: Dermoscopy imaging
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Moxonidine on Blood Pressure and Regression of Early Target Organ Damage in Young Subjects With Abdominal Obesity and Hypertension
Status: UNKNOWN
Conditions: Abdominal Obesity|Hypertension
Interventions: DRUG: Moxonidine|DRUG: Irbesartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of COBI-boosted Atazanavir Versus Ritonavir-boosted Atazanavir Each Administered With Emtricitabine/Tenofovir Disoproxil Fumarate in HIV-1 Infected, Antiretroviral Treatment-Naive Adults
Status: COMPLETED
Conditions: HIV|HIV Infections
Interventions: DRUG: COBI|DRUG: RTV|DRUG: ATV|DRUG: FTC/TDF|DRUG: COBI placebo|DRUG: RTV placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Conbercept Injection in Treatment of Severe Proliferative Diabetic Retinopathy
Status: COMPLETED
Conditions: Proliferative Diabetic Retinopathy|Tractional Retinal Detachment
Interventions: DRUG: Conbercept
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of Drug-eluting and Bare Metal Stents in Bypass Graft Lesions
Status: COMPLETED
Conditions: Arteriosclerosis of Arterial Coronary Artery Bypass Graft
Interventions: DEVICE: sirolimus-eluting stent|DEVICE: paclitaxel-eluting stent|DEVICE: biodegradable-polymer-based sirolimus-eluting stent|DEVICE: bare metal stents
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Effects Of Gaze Stability Exercises And Optokinetic Exercises In Patients With Vestibular Hypofunction
Status: RECRUITING
Conditions: Vestibular Disorder
Interventions: OTHER: Gaze Stability Exercises|OTHER: Optokinetic Exercises|OTHER: Routine Physical Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Ocrelizumab in Combination With Methotrexate Compared With Infliximab Plus Methotrexate in Patients With Active Rheumatoid Arthritis Currently Responding Inadequately to Etanercept or Adalimumab
Status: TERMINATED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Infliximab|DRUG: Methotrexate|DRUG: Methylprednisolone|DRUG: Ocrelizumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dexamethasone Compared to Ondansetron and Dexamethasone for Prophylaxis of Postoperative Vomiting in Children
Status: COMPLETED
Conditions: Vomiting Postoperative
Interventions: DRUG: Dexamethasone and ondasetron|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of USL for Dry Eye Disease
Status: NOT_YET_RECRUITING
Conditions: Dry Eye Disease
Interventions: DRUG: USL|DRUG: USL Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Selenium Supplementation on Glycemic Control in Patients With Type 2 Diabetes or Prediabetes
Status: UNKNOWN
Conditions: Type 2 Diabetes|PreDiabetes
Interventions: DIETARY_SUPPLEMENT: Se-yeast|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of MabThera (Rituximab) in Patients With Rheumatoid Arthritis and an Inadequate Response to Methotrexate
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: rituximab [MabThera/Rituxan]|DRUG: methotrexate|DRUG: methylprednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Ranolazine and Exercise on Daily Physical Activity Trial
Status: COMPLETED
Conditions: Chronic Stable Angina
Interventions: DRUG: Ranolazine|BEHAVIORAL: Aerobic Exercise|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Community-Based Model for Delivery of Antiretroviral Therapy in Cambodia
Status: RECRUITING
Conditions: HIV Infections|AIDS
Interventions: OTHER: Community-based ART delivery (CAD)|OTHER: ART multi-month dispensing (MMD)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Safety Study of a Shorter (Hypofractionated) Radiotherapy for the Prostate Bed With or Without the Pelvic Lymph Nodes
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: RADIATION: hypofractionated helical IMRT|RADIATION: hypofractionated helical IMRT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, and Pharmacokinetics of Single Ascending Doses of Simotinib Hydrochloride in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Simotinib Hydrochloride|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testing the Combination of the Anti-cancer Drugs ZEN003694 (ZEN-3694) and Talazoparib in Patients With Advanced Solid Tumors, The ComBET Trial
Status: RECRUITING
Conditions: Advanced Malignant Solid Neoplasm|Metastatic Malignant Solid Neoplasm|Unresectable Malignant Solid Neoplasm
Interventions: DRUG: BET Bromodomain Inhibitor ZEN-3694|PROCEDURE: Biopsy|PROCEDURE: Biospecimen Collection|PROCEDURE: Diagnostic Imaging|DRUG: Talazoparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effect of Itraconazole on the Pharmacokinetics of Alisertib in Participants With Advanced Solid Tumors or Relapsed/Refractory Lymphoma
Status: COMPLETED
Conditions: Advanced Solid Tumors|Relapsed/Refractory Lymphoma
Interventions: DRUG: Alisertib|DRUG: Itraconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of a Levonorgestrel 52 mg Intrauterine System for the Treatment of Heavy Menstrual Bleeding
Status: COMPLETED
Conditions: Menorrhagia
Interventions: COMBINATION_PRODUCT: Levonorgestrel 52 mg intrauterine system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Phase IVd of Inactivated Enterovirus 71 Vaccine
Status: UNKNOWN
Conditions: Hand, Foot and Mouth Disease (HFMD)
Interventions: BIOLOGICAL: EV71 and two measles attenuated live vaccine|BIOLOGICAL: EV71 and attenuated Japanese encephalitis vaccine|BIOLOGICAL: two measles attenuated live vaccine|BIOLOGICAL: live attenuated Japanese encephalitis vaccine|BIOLOGICAL: EV71 vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Raltegravir Added to Stable HAART in HIV-1 Infected Subjects With Viral Suppression and Low CD4 Recovery
Status: TERMINATED
Conditions: HIV Infections
Interventions: DRUG: Raltegravir|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Trial of Seribantumab Plus Fulvestrant in Postmenopausal Women With Metastatic Breast Cancer
Status: TERMINATED
Conditions: Metastatic Breast Cancer
Interventions: DRUG: Seribantumab|DRUG: Fulvestrant|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Panitumumab-IRDye800 and 89Zr-Panitumumab in Identifying Metastatic Lymph Nodes in Patients With Squamous Cell Head and Neck Cancer
Status: COMPLETED
Conditions: Squamous Cell Carcinoma of the Head and Neck|Carcinoma of the Head and Neck
Interventions: DRUG: Panitumumab-IRDye800|DRUG: 89-Zirconium (Zr-89) Panitumumab|DEVICE: Pinpoint IR IR9000 fluorescence imaging system (FIS)|DEVICE: SPY-PHI IR9000 fluorescence imaging system (FIS)|DEVICE: Explorer Air camera|DEVICE: PDE-NEO II camera|DEVICE: FIS-00 fluorescence imaging system (FIS)|DEVICE: Da Vinci Firefly Imaging System|DEVICE: IGP-ELVIS-v4 Macroscopic Specimen Imager|DEVICE: Vevo 3100 LAZR-X|DEVICE: Pearl Triology Imaging System|DEVICE: Odyssey CLx Imaging System|DEVICE: Leica fluorescence microscope
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Evaluate Effect of IN-A001 on Pharmacokinetics of Tacrolimus in Healthy Volunteers
Status: UNKNOWN
Conditions: Healthy
Interventions: DRUG: Tacrolimus|DRUG: IN-A001(Tegoprazan)|DRUG: IN-A001(Tegoprazan) + Tacrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Regenerative Endodontics Therapy for Single-rooted Mature Permanent Tooth With Pulp Necrosis
Status: UNKNOWN
Conditions: Pulp Necrosis
Interventions: OTHER: PRF|OTHER: BC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Telerehabiliation Intervention Effect of the Tai Chi Exercise on Elderly With Sarcopenia
Status: RECRUITING
Conditions: Sarcopenia
Interventions: BEHAVIORAL: AI telerehabilitation - Tai Chi|BEHAVIORAL: general telerehabilitation - Tai Chi|BEHAVIORAL: traditional rehabilitation - Tai Chi|BEHAVIORAL: AI telerehabilitation - Yi Jin Jing|BEHAVIORAL: general telerehabilitation - Yi Jin Jing|BEHAVIORAL: traditional rehabilitation - Yi Jin Jing|BEHAVIORAL: AI telerehabilitation - Ba Duan Jin|BEHAVIORAL: general telerehabilitation - Ba Duan Jin|BEHAVIORAL: traditional rehabilitation - Ba Duan Jin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Value of Rapid on Site Evaluation During EBUS-guided TBNA in the Diagnosis of Mediastinal Lesions
Status: COMPLETED
Conditions: Mediastinum
Interventions: PROCEDURE: EBUS TBNA of mediastinal lesions or lymph nodes
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Novel Crown-cut Biopsy Needle (FNB) vs Standard Aspiration Needle (FNA) for EUS-guided Diagnosis of SPLs
Status: UNKNOWN
Conditions: Pancreas Neoplasm|Pancreas Cancer
Interventions: DEVICE: ProControl, MediGlobe|DEVICE: TopGain, Medi-Globe
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: CD19.CAR-multiVSTs for Patients With CD19+ B-ALL or NHL Undergoing Related Allogeneic HSCT (CARMA)
Status: WITHDRAWN
Conditions: Non-hodgkin Lymphoma|Acute Lymphoblastic Leukemia
Interventions: BIOLOGICAL: CD19.CAR-multiVST for Group A|BIOLOGICAL: CD19.CAR-multiVST for Group B
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Remote Ischemic Preconditioning as a New Method of Nephroprotection
Status: COMPLETED
Conditions: Acute Kidney Injury
Interventions: PROCEDURE: remote ischemic preconditioning|PROCEDURE: no - remote ischemic preconditioning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Assessment of the Effectiveness of Low-Level Laser Therapy on the Hands of Patients With Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: OTHER: phototherapy|OTHER: phototherapy placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The 'Outdoor Rehab-Fit' App-based Physical Activity Education Intervention for Frail Older Adults in Hong Kong
Status: RECRUITING
Conditions: Physical Inactivity|Frailty
Interventions: BEHAVIORAL: mHealth|BEHAVIORAL: Health Talk
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Combined Spinal Epidural Anesthesia and General Anesthesia for Laparoscopic Cholecystectomy
Status: COMPLETED
Conditions: Gall Stone Disease|Polyp
Interventions: PROCEDURE: combined anesthesia|PROCEDURE: general anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Assessing the Efficacy of Four Drug Combinations as the Next First-line Therapy for Uncomplicated Malaria in Malawi
Status: COMPLETED
Conditions: Malaria, Falciparum
Interventions: DRUG: sulfadoxine-pyrimethamine|DRUG: amodiaquine plus sulfadoxine-pyrimethamine|DRUG: amodiaquine plus artesunate|DRUG: chlorproguanil-dapsone plus artesunate|DRUG: lumefantrine-artemether
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study of Neoadjuvant Chemotherapy Plus Durvalumab (MEDI4736) and Tremelimumab in Advanced-stage Ovarian Cancer (TRU-D)
Status: UNKNOWN
Conditions: Ovarian Cancer Stage IIIC|Ovarian Cancer Stage IV
Interventions: DRUG: Neoadjuvant chemotherapy+Durvalumab+Tremelimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Omacor on Triglycerides in HIV Infected Subjects
Status: TERMINATED
Conditions: Hyper-Triglyceridemia
Interventions: DRUG: Omacor|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Olaratumab (IMC-3G3) in Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: BIOLOGICAL: Olaratumab|DRUG: Mitoxantrone|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: FT500 as Monotherapy and in Combination With Immune Checkpoint Inhibitors in Subjects With Advanced Solid Tumors
Status: COMPLETED
Conditions: Advanced Solid Tumors|Lymphoma|Gastric Cancer|Colorectal Cancer|Head and Neck Cancer|Squamous Cell Carcinoma|EGFR Positive Solid Tumor|HER2-positive Breast Cancer|Hepatocellular Carcinoma|Small Cell Lung Cancer|Renal Cell Carcinoma|Pancreas Cancer|Melanoma|NSCLC|Urothelial Carcinoma|Cervical Cancer|Microsatellite Instability|Merkel Cell Carcinoma
Interventions: DRUG: FT500|DRUG: Nivolumab|DRUG: Pembrolizumab|DRUG: Atezolizumab|DRUG: Cyclophosphamide|DRUG: Fludarabine|DRUG: IL-2
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Enzalutamide in Combination With Gemcitabine and Cisplatin in Bladder Cancer
Status: COMPLETED
Conditions: Bladder Cancer|Carcinoma, Transitional Cell|Renal Pelvis Cancer|Ureter Cancer|Urethra Cancer
Interventions: DRUG: Enzalutamide|DRUG: Cisplatin|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Prevalence of Vitamin D Deficiency and Effects of Vitamin D Supplementation in HIV-1 Infected Patients
Status: UNKNOWN
Conditions: Vitamin D Deficiency|HIV Infections
Interventions: DRUG: colecalciferol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Brentuximab Vedotin and BeEAM High-dose Chemotherapy in Lymphomas
Status: SUSPENDED
Conditions: Lymphoma
Interventions: DRUG: Brentuximab Vedotin|DRUG: BeEAM Regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acute Effects of Inspiratory Muscle Exercise on Glucose Level and Glucose Variability in Patients With Type 2 Diabetes.
Status: UNKNOWN
Conditions: Diabetes Mellitus, Type 2
Interventions: DEVICE: Inspiratory muscle exercise|DEVICE: Inspiratory muscle exercise placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: TMC114-TiDP29-C169: Bioavailability and Pharmacokinetics Trial Comparing Darunavir Pediatric Suspension Formulation to Current Darunavir Tablet
Status: COMPLETED
Conditions: Pharmacokinetics
Interventions: DRUG: Darunavir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Teclistamab-Daratumumab and Talquestamab-Daratumumab in Newly Diagnosed High-risk Multiple Myeloma
Status: RECRUITING
Conditions: High-Risk de Novo Multiple Myeloma
Interventions: DRUG: Daratumumab|DRUG: Bortezomib|DRUG: Lenalidomide|DRUG: Teclistamab|DRUG: Talquetamab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Lumigan® 0.01% in Patients With Primary Open Angle Glaucoma (POAG) or Ocular Hypertension (OHT)
Status: COMPLETED
Conditions: Glaucoma, Open-Angle|Ocular Hypertension
Interventions: DRUG: bimatoprost 0.01% ophthalmic solution
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study in Healthy Men to Test Whether BI 1015550 Influences the Amount of Nintedanib and Pirfenidone in the Blood
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BI 1015550|DRUG: Nintedanib|DRUG: Pirfenidone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Use of OTSC in LBGDU to Standard Endoscopic Hemostatic Methods
Status: WITHDRAWN
Conditions: Bleeding Peptic Ulcer
Interventions: DEVICE: Over-the-scope Clips|DEVICE: Hemo-clipping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Diagnostic Value of the TPD System in Determining ADHF Causing Acute Dyspnea
Status: TERMINATED
Conditions: ADHF
Interventions: DEVICE: Lung Doppler Signals
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Early Prediction of Spontaneous Patent Ductus Arteriosus (PDA) Closure and PDA-Associated Outcomes
Status: ACTIVE_NOT_RECRUITING
Conditions: Patent Ductus Arteriosus|Preterm Infant|Bronchopulmonary Dysplasia|Neurodevelopmental Abnormality
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Standard Injections Versus Reduced Injections for Intravesical onabotulinumtoxinA Treatment of Overactive Bladder
Status: RECRUITING
Conditions: Overactive Bladder
Interventions: DRUG: onaBoNT-A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study to Test the Effectiveness of an Investigational Drug to Treat People That Have Major Depressive Episodes When They Have Bipolar 1 Depression
Status: COMPLETED
Conditions: Depressive Episode|Bipolar 1 Depression
Interventions: DRUG: SEP-4199 200 mg|DRUG: SEP-4199 400 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Gene Modified Donor T Cell Infusion After Stem Cell Transplant for Non-Malignant Diseases
Status: TERMINATED
Conditions: Primary Immune Deficiency Disorders|Hemophagocytic Lymphohistiocytosis|Inherited Bone Marrow Failure Syndrome|Hemoglobinopathies|Metabolic Disorders
Interventions: BIOLOGICAL: BPX-501 and Rimiducid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Safety, Tolerability and Immunogenicity of Gardasil®9 in Immunocompromised Patients
Status: COMPLETED
Conditions: Human Papilloma Virus|Hiv|Organ Transplants
Interventions: BIOLOGICAL: 9-valent HPV vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Pilot Feasibility Trial of a Tailored Intervention to Improve Adherence in Adolescents and Young Adults With Cancer
Status: RECRUITING
Conditions: Cancer|Adherence, Medication
Interventions: BEHAVIORAL: Tailored Program|BEHAVIORAL: Feedback Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Management of Frailty in Older Adults With Turmeric and Tulsi Supplements
Status: UNKNOWN
Conditions: Frail Elderly Syndrome
Interventions: DRUG: C. longa, curcuminoids , Z. officianale, O. sanctum along with 200 ml of Milk|OTHER: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effectiveness of STELARA ™ (USTEKINUMAB) in the Treatment of Scalp Psoriasis
Status: UNKNOWN
Conditions: Scalp Psoriasis|Plaque Psoriasis
Interventions: DRUG: Ustekinumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Remote Breast Cancer Screening Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer|Mass Screening|Cancer Screening|Ultrasound Imaging|AI (Artificial Intelligence)
Interventions: DIAGNOSTIC_TEST: Conventional-reading|DIAGNOSTIC_TEST: Second-reading|DIAGNOSTIC_TEST: Concurrent-reading|DIAGNOSTIC_TEST: Tow views-reading|DIAGNOSTIC_TEST: Handheld US-screening
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: On-Eye Evaluation of Contact Lens Axis Location
Status: COMPLETED
Conditions: Myopia|Astigmatism|Refractive Error
Interventions: DEVICE: Delefilcon A toric contact lens T1|DEVICE: Delefilcon A toric contact lens T2|DEVICE: Delefilcon A toric contact lens T3|DEVICE: Delefilcon A toric contact lens T4|DEVICE: Delefilcon A toric contact lens T5|DEVICE: Delefilcon A toric contact lens T6
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: Insulin Resistance and Testosterone in Women
Status: COMPLETED
Conditions: Insulin Resistance|Postmenopause
Interventions: DRUG: metformin|DRUG: leuprolide injection|DRUG: placebo pill|DRUG: placebo injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing Different Regional Blocks for Analgesia After Off-pump Cardiac Surgery
Status: ACTIVE_NOT_RECRUITING
Conditions: Analgesia
Interventions: OTHER: Erector Spinae Plane Block|OTHER: Superficial Parasternal Intercostal Plane Block combined with Rectus Sheath Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Norepinephrine in Patients With Congenital Insensitivity to Pain and Anhidrosis
Status: WITHDRAWN
Conditions: HSAN Type IV
Interventions: DRUG: Droxidopa (L-DOPS)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy, Tirapazamine, and Radiation Therapy in Treating Patients With Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DRUG: carboplatin|DRUG: paclitaxel|DRUG: tirapazamine|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: The Impact of Zinc Supplementation on Left Ventricular Function in Nonischemic Cardiomyopathy
Status: COMPLETED
Conditions: Heart Failure|Cardiomyopathies
Interventions: DRUG: Zinc Acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness Fluoride Varnishes in Children With Early Childhood Caries
Status: COMPLETED
Conditions: Early Childhood Caries
Interventions: DRUG: Sodium Fluoride|DRUG: Sodium Fluoride with TCP|DRUG: Sodium Fluoride with CXP|DRUG: Sodium Fluoride with CPP-ACP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: The Metabolic Effects of Acute Hyperglycemia in Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Actrapid (human insulin)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Taselisib and Enzalutamide in Treating Patients With Androgen Receptor Positive Triple-Negative Metastatic Breast Cancer
Status: TERMINATED
Conditions: Estrogen Receptor Negative|Estrogen Receptor Positive|HER2/Neu Negative|Progesterone Receptor Negative|Progesterone Receptor Positive|Stage IV Breast Cancer|Triple-Negative Breast Carcinoma
Interventions: OTHER: Biomarker Analysis|DRUG: Enzalutamide|OTHER: Pharmacological Study|DRUG: Taselisib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transvaginal NOTES Nephrectomy Versus Conventional Laparoscopic Nephrectomy
Status: UNKNOWN
Conditions: Renal Disease
Interventions: PROCEDURE: transvaginal NOTES nephrectomy|PROCEDURE: conventional laparoscopic nephrectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Snoezelen-Based Occupational Therapy Intervention on Sleep and Behavior Problems in Infant at Risk of Autism
Status: COMPLETED
Conditions: Autism Spectrum Disorder|Sleep Disorder|Behavior Problem
Interventions: BEHAVIORAL: Snoezelen-Based Occupational Therapy Intervention Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Bone Marrow Cell Transplantation in Humans Myocardial Infarction
Status: UNKNOWN
Conditions: Acute Myocardial Infarction
Interventions: PROCEDURE: cell therapy, bone marrow derived stem cell
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The VIA Family 2.0 - a Family Based Intervention for Families With Parental Mental Illness
Status: NOT_YET_RECRUITING
Conditions: Child|Parents|Mental Disorder|Child of Impaired Parents|Preventive Health Services
Interventions: OTHER: VIA Family 2.0
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Specific Anti-HBV Vaccine Response After Vaccination in Patients Requiring Anti-CD20 Monoclonal Antibodies
Status: COMPLETED
Conditions: HBV
Interventions: BIOLOGICAL: o receive treatment with anti-CD20 (rituximab or ocrelizumab) and to be vaccinated against hepatitis B
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Blood Samples From Patients With Malignant Melanoma, Metastatic Breast Cancer, Advanced Lung Cancer, Pancreatic Cancer, or Colorectal Cancer.
Status: COMPLETED
Conditions: Breast Cancer|Colorectal Cancer|Lung Cancer|Melanoma (Skin)|Pancreatic Cancer
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Potassium Canrenoate in Brain-dead Organ Donors: Randomized Controlled Clinical Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Brain-dead Organ Donors
Interventions: DRUG: IV Potassium Canrenoate|DRUG: IV Sodium Chloride 0.9 %
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Lenalidomide and GM-CSF in Treating Patients With Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: BIOLOGICAL: sargramostim|DRUG: lenalidomide|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT