pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: To Develop Methods for the Rehabilitation of Chronic Gastroduodenal Pathology in Children.
Status: ACTIVE_NOT_RECRUITING
Conditions: Gastritis Chronic|Gastroduodenitis|Peptic Ulcer|Duodenal Ulcer
Interventions: DRUG: Enteral oxygen therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Lenacapavir and Emtricitabine/Tenofovir Disoproxil Fumarate (F/TDF) for Prevention of HIV in People Who Inject Drugs (HPTN 103)
Status: RECRUITING
Conditions: Pre-Exposure Prophylaxis of HIV Infection
Interventions: DRUG: Lenacapavir Injection|DRUG: Lenacapavir Tablet|DRUG: Emtricitabine/tenofovir disoproxil fumarate (F/TDF)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Randomized Study in Children and Adolescents With Migraine: Acute Treatment
Status: RECRUITING
Conditions: Pediatric Migraine
Interventions: DRUG: Rimegepant/BHV3000|DRUG: Matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Nicotine Delivery Systems: Research & Treatment
Status: TERMINATED
Conditions: Smoking
Interventions: DRUG: Nicotine gum - 2 mg and 4 mg|DRUG: Nicotine lozenges - 2 mg and 4 mg|DRUG: Nicotine inhaler (4 mg yield) - low and high "dosage" by frequency of puffing|OTHER: Computer learning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Effects of Single Agent Niraparib and Niraparib Plus Programmed Cell Death-1 (PD-1) Inhibitors in Non-Small Cell Lung Cancer Participants
Status: COMPLETED
Conditions: Neoplasms
Interventions: DRUG: Niraparib|BIOLOGICAL: Pembrolizumab|BIOLOGICAL: TSR-042 (Dostarlimab)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Accuracy of the Drager Dual-sensor Temperature Measurement System
Status: COMPLETED
Conditions: Hypothermia; Anesthesia
Interventions: DEVICE: Draeger double-sensor|DEVICE: Esophageal stethoscope temperature sensor|DEVICE: Foley catheter temperature sensor
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Intravenous Insulin in Patients With Diabetes After Percutaneous Coronary Intervention (PCI)
Status: TERMINATED
Conditions: Diabetes Mellitus|Percutaneous Coronary Intervention
Interventions: DRUG: Intravenous Insulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Blended Care Versus Face-to-Face Therapy for Depression
Status: ACTIVE_NOT_RECRUITING
Conditions: Major Depressive Disorder
Interventions: BEHAVIORAL: B-DIT|BEHAVIORAL: B-CBT|BEHAVIORAL: DIT|BEHAVIORAL: Cognitive Behavioral Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II Study of Single-Dose Image-Guided Radiotherapy (SDRT) for Prostate Cancer
Status: RECRUITING
Conditions: Prostate Cancer
Interventions: RADIATION: IGRT 24 Gy Single dose|PROCEDURE: Image-guided, volumetric intensity-modulated arc radiotherapy (IGRT-VMAT)|DEVICE: Rectal balloon with air filling|DEVICE: Urethral catheter loaded with beacon transponders
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Metabolically Optimized, Non-cytotoxic Low Dose Weekly Decitabine/Venetoclax in MDS and AML
Status: RECRUITING
Conditions: MDS|AML|CMML
Interventions: DRUG: Venetoclax|DRUG: Decitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Roy Adaptation-Based Nursing Intervention
Status: COMPLETED
Conditions: Hemodialysis Complication|Stress Disorders, Post-Traumatic|Psychosocial Impairment|Self Neglect
Interventions: BEHAVIORAL: The Effect of Roy Adaptation-Based Nursing Intervention on Stress, Psychosocial Adjustment and Self-Care Power in Hemodialysis Patients: A Randomized Controlled Experimental Study
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Targeted Antimalarial Drug Administration for Seasonal Migrant Populations in Amhara Region, Ethiopia
Status: NOT_YET_RECRUITING
Conditions: Plasmodium Falciparum|Malaria
Interventions: DRUG: Dihydroartemisinin-piperaquine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Stabilometry and Plantar Pressures Changes After Progressive Pressure Release in Flexor Digitoum Brevis in Latent Trigger Points
Status: COMPLETED
Conditions: Bilateral Latent Myofascial Trigger Points of Flexor Digitorum Brevis
Interventions: PROCEDURE: progressive pressure release
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial To Assess Efficacy Of A Chimeric Skin In Patients With Epidermolysys Bullosa
Status: COMPLETED
Conditions: EPIDERMOLYSIS BULLOSA
Interventions: DRUG: CX501|DEVICE: Occlusive non adherent dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: IRB-HSR# 13957: IV Lidocaine for Patients Undergoing Primary Breast Cancer Surgery:
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Placebo|DRUG: Lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Treatment Effectiveness of Combined tDCs and Neurofeedback (NF) for Patients With Cognitive Deficits After Stroke
Status: COMPLETED
Conditions: Stroke|Cognitive Impairment
Interventions: DEVICE: tDCS & neurofeedback|DEVICE: neurofeedback|DEVICE: sham neurofeedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vitamin D Supplementation in CAD and Postchallenge Hyperglycemia
Status: TERMINATED
Conditions: Coronary Artery Disease|Postprandial Hyperglycemia|Vitamin D Deficiency
Interventions: DRUG: vitamin D
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: "Electro Acupuncture in the Treatment and Management of Chemotherapy Induced Peripheral Neuropathy"
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: DEVICE: Acupuncture|DEVICE: Sham Acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Levels of Diagnostic and Therapeutic Intervention in Hospitalized Patients
Status: NOT_YET_RECRUITING
Conditions: Acute Disease
Interventions: OTHER: Levels of Diagnostic and Therapeutic Intervention tool by Fontecha and col.|OTHER: Usual clinical practice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Distribution, Pharmacokinetics and Extent of Sensory Blockade in ESP Blocks
Status: COMPLETED
Conditions: Distribution of Ropivacaine in Erector Spinae Plane Block
Interventions: DRUG: Ropivacaine|DRUG: Epinephrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Circulating Tumor Cells to Guide Chemotherapy for Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer Ductal Infiltrating Metastatic
Interventions: BIOLOGICAL: Blood sampling|OTHER: Usual clinical and radiological criteria
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Impact of Active Heating on Maternal and Neonatal Well-being
Status: COMPLETED
Conditions: Hypothermia
Interventions: OTHER: İntervention 1 group (underbody heater group only)|OTHER: İntervention 2 group (group using both underbody heater and heated iv liquid)|OTHER: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of Combination of Ultrasound and Flouroscopy Guidance in Caudal Epidural Injections
Status: UNKNOWN
Conditions: Radiculopathy|Lumbar Disc Herniation|Spinal Stenosis
Interventions: PROCEDURE: floroscopy|PROCEDURE: ultrasound+fluoroscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effects of Lactoferrin-enriched Whey on Iron Status in Females
Status: RECRUITING
Conditions: Serum Ferritin
Interventions: DIETARY_SUPPLEMENT: Lactoferrin, iron and B12 in Whey Protein|DIETARY_SUPPLEMENT: Lactoferrin, Iron and B12 in Rice Protein|DIETARY_SUPPLEMENT: Lactoferrin, Iron and B12 in Maltrodextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Safety of BF2.649 in Excessive Daytime Sleepiness (EDS) in Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DRUG: BF2.649 (Pitolisant)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cochlear Implant With Dexamethasone Eluting Electrode Array
Status: ACTIVE_NOT_RECRUITING
Conditions: Sensorineural Hearing Loss|Bilateral Hearing Loss
Interventions: DEVICE: CI632D|DEVICE: CI632
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Dose Escalation, Expansion Study of Vofatamab (B-701) in Treatment of Locally Advanced or Metastatic Urothelial Cell Carcinoma
Status: TERMINATED
Conditions: Locally Advanced or Metastatic Urothelial Cell Carcinoma|Urinary Bladder Disease|Urological Diseases
Interventions: DRUG: Vofatamab|DRUG: Docetaxel|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Agaricus Blazei Murill (ABM) in Patients With Inflammatory Bowel Disease (IBD)
Status: COMPLETED
Conditions: Inflammatory Bowel Disease
Interventions: DIETARY_SUPPLEMENT: AndoSan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hot Water Immersion Therapy for Mental Health
Status: UNKNOWN
Conditions: Anxiety Disorders|Depression|Post-traumatic Stress Disorder|Heat|Water Immersion
Interventions: PROCEDURE: lower-limb hot water immersion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Preventing Brain Injury in Infants With Congenital Heart Disease
Status: COMPLETED
Conditions: Cyanotic Congenital Heart Disease
Interventions: DRUG: Topiramate|OTHER: No medication, but routine heart surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparison of Two Different Catheter Withdrawal Technique
Status: COMPLETED
Conditions: Embryo|Catheter Site Discharge
Interventions: PROCEDURE: Embryo transfer any further manipulation|PROCEDURE: Embryo transfer with catheter Manipulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Dose-Finding Study to Evaluate the Efficacy and Safety of GSK3858279 in Adults With Knee Osteoarthritis Pain
Status: RECRUITING
Conditions: Pain
Interventions: DRUG: GSK3858279|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prevalence of Atrial Fibrillation in Cryptogenic Stroke With Patent Foramen Ovale Closure (PFO-AF) Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Patent Foramen Ovale|Atrial Fibrillation|Stroke
Interventions: DEVICE: Implantation of Holter device|PROCEDURE: Percutaneous PFO closure
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Immune Therapy and Analytical Treatment Interruption in HIV+ Participants Who Received an Allogeneic Stem Cell Transplantation
Status: WITHDRAWN
Conditions: HIV Infection
Interventions: DRUG: Analytical Treatment Interruption + bNAbs infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Lurasidone Pediatric Autism Study
Status: COMPLETED
Conditions: Autism
Interventions: DRUG: Lurasidone 20 mg daily|DRUG: Lurasidone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Metacognitive Therapy Versus Cognitive Behavioral Therapy for Mixed Anxiety Disorders: A Randomized Controlled Trial.
Status: COMPLETED
Conditions: Mixed Anxiety Disorders
Interventions: BEHAVIORAL: Metacognitive therapy|BEHAVIORAL: Cognitive behavioral therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A RCT to Establish the Effectiveness of Intermittent Pneumatic Compression to Prevent Post Stroke DVT
Status: COMPLETED
Conditions: Stroke
Interventions: DEVICE: Intermittent Pneumatic compression|OTHER: Routine care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Genotype, Metabotype and Diet in a Cohort of Children and Adolescents From the Southeast of Spain.
Status: COMPLETED
Conditions: Genotype, Metabotype and Dietary Habits
Interventions: OTHER: Walnuts|OTHER: Pomegranate juice
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Trametinib and Docetaxel in Treating Patients With Recurrent or Stage IV KRAS Mutation Positive Non-small Cell Lung Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: KRAS Gene Mutation|Recurrent Lung Non-Small Cell Carcinoma|Stage IV Lung Non-Small Cell Cancer AJCC v7
Interventions: DRUG: Docetaxel|OTHER: Laboratory Biomarker Analysis|DRUG: Trametinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Strengthening Instrumental Extinction to Prevent Smoking Relapse (VLNCCue)
Status: COMPLETED
Conditions: Cigarette Smoking
Interventions: DRUG: Nicotine Patch|DRUG: SPECTRUM Nicotine Research Cigarettes (0.07 mg)|BEHAVIORAL: MCE+|BEHAVIORAL: MCE-
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study on the Safety and Effectiveness of Varian ProBeam Proton Therapy Equipment in the Treatment of Solid Tumors
Status: COMPLETED
Conditions: Solid Tumor|Radiation Therapy|Proton Therapy
Interventions: DEVICE: Proton radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mesh Fixation With Intraperitoneal Tisseel
Status: COMPLETED
Conditions: Postoperative Pain|Ventral Hernia
Interventions: PROCEDURE: tack fixation of mesh|PROCEDURE: glue fixation of mesh
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Sorafenib and Ifosfamide in Treating Patients With High-Grade Soft Tissue Sarcoma or Bone Sarcoma That Can Be Removed by Surgery
Status: TERMINATED
Conditions: Sarcoma
Interventions: DRUG: sorafenib|DRUG: Ifosfamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Study the Safety and Efficacy of Midodrine With Albumin Versus Albumin Alone in Hepatic Hydrothorax
Status: COMPLETED
Conditions: Hepatic Hydrothorax
Interventions: DRUG: Midodrine|BIOLOGICAL: Albumin|DRUG: Diuretics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Assess the Efficacy and Safety of Furmonertinib Versus Placebo, in Patients With Epidermal Growth Factor Receptor Mutation Positive Stage II-IIIA Non-small Cell Lung Carcinoma, Following Complete Tumour Resection With or Without Adjuvant Chemotherapy
Status: NOT_YET_RECRUITING
Conditions: Non-small Cell Lung Carcinoma
Interventions: DRUG: Drug: Furmonertinib 80 mg|DRUG: Furmonertinib 80 mg placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Opioid Reduction Program for Total Knee Replacement Patients
Status: COMPLETED
Conditions: Knee Injuries|Knee Injuries and Disorders|Opioid Use
Interventions: BEHAVIORAL: Opioid Reduction Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Psilocybin and Depression
Status: UNKNOWN
Conditions: Severe Depression
Interventions: DRUG: Psilocybin|DRUG: Ketamine (Ketalar)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Targeted AntiBiotics for Chronic Pulmonary Diseases
Status: TERMINATED
Conditions: COPD|Respiratory Tract Infections|Pseudomonas Aeruginosa|Bronchiectasis|Asthma
Interventions: DRUG: Piperacillin/tazobactam|DRUG: Ciprofloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study of Neuroinflammation in Multiple Sclerosis by PET-MRI Imaging Using the Radiotracer ([18F]-DPA-714) : a Multicentre Cohort Study (INFLANET)
Status: NOT_YET_RECRUITING
Conditions: Multiple Sclerosis
Interventions: RADIATION: PET-MRI with [18F]-DPA-714
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effects of Bran Size on Glycemic Responses
Status: COMPLETED
Conditions: Potential Abnormality of Glucose Tolerance|Appetitive Behavior
Interventions: OTHER: Glucose as reference food|OTHER: White bread as reference food|OTHER: Bread enriched with coarse wheat bran|OTHER: Bread enriched with fine wheat bran|OTHER: Bread enriched with fine wheat bran and carob seed flour
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Placental Transfusion in the 'Natural' Delivery: Effect of Early and Late Umbilical Cord Clamping
Status: UNKNOWN
Conditions: Hematocrit Anemia|Acidosis
Interventions: PROCEDURE: Umbilical cord clamping at birth.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Erlotinib Pharmacokinetics During Doxycycline Treatment for Erlotinib-induced Rash
Status: WITHDRAWN
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: doxycycline
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Oxidative Stress on Muscle Dysfunction in Hemodialysis Patient
Status: TERMINATED
Conditions: Chronic Renal Failure Requiring Hemodialysis
Interventions: PROCEDURE: renal transplantation|OTHER: No intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Post-market, Prospective Evaluation of PHOTO-oxidized Bovine Pericardium in Vascular Surgery
Status: COMPLETED
Conditions: Vascular Diseases|Peripheral Arterial Disease|Hemodialysis Access Failure (Disorder)|Carotid Artery Diseases|Abdominal Aortic Aneurism
Interventions: DEVICE: PhotoFix
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Find the Best Dose of ASP5354 to Show Lymph Nodes in People With Breast Cancer or Melanoma During Surgery
Status: TERMINATED
Conditions: Sentinel Lymph Node Biopsy|Breast Cancer|Melanoma
Interventions: DRUG: pudexacianinium chloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Pulmonary Vein Isolation With Versus Without Continued Antiarrhythmic Drug Treatment in Subjects With Recurrent Atrial Fibrillation
Status: UNKNOWN
Conditions: Atrial Fibrillation
Interventions: OTHER: PVI-ADT|OTHER: PVI+ADT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PK Study of YH22189 FDC Compared to Combination of Telmisartan/Amlodipine and Rosuvastatin
Status: TERMINATED
Conditions: Hypertension|Hyperlipidemia
Interventions: DRUG: YH22189|DRUG: Twynsta 80/10mg|DRUG: Crestor 20mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: This is a Retrospective Observational Study Looking at the Characteristics and Outcomes of Participants Taking Inflectra Using the CorEvitas Rheumatoid Arthritis Registry
Status: COMPLETED
Conditions: Arthritis, Rheumatoid
Interventions: DRUG: Inflectra|DRUG: Inflectra
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Peanut Consumption on Postprandial Inflammation, Glucose and Triglycerides
Status: COMPLETED
Conditions: Cardiovascular Disease
Interventions: DIETARY_SUPPLEMENT: Peanuts|DIETARY_SUPPLEMENT: Glucose and whipping cream|DIETARY_SUPPLEMENT: Oil Blend
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Sympathetic and Vascular Function in Takotsubo Syndrome
Status: COMPLETED
Conditions: Takotsubo Cardiomyopathy
Interventions: DRUG: Metoprolol Injection|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Medical Management of Late Intrauterine Death.
Status: COMPLETED
Conditions: Cervical Pregnancy|Maternal Care for Late Fetal Death
Interventions: DRUG: Isosorbide Dinitrate|DRUG: Misoprostol|DRUG: Oxytocin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing BL-B01D1 With Chemotherapy of Physician's Choice in Patients With Unresectable Locally Advanced or Metastatic Triple-Negative Breast Cancer
Status: RECRUITING
Conditions: Triple-Negative Breast Cancer
Interventions: DRUG: BL-B01D1|DRUG: Eribulin|DRUG: Vinorelbine|DRUG: Gemcitabine|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Quality of Life and Function of Patients With Pelvic Tumors After Undergoing Hemipelvectomy
Status: RECRUITING
Conditions: Malignant Primary Pelvic Neoplasm
Interventions: OTHER: Electronic Health Record Review|OTHER: Physical Performance Testing|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Efficacy of Oral GKT137831 in Patient With Type 2 Diabetes and Albuminuria
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus With Diabetic Nephropathy
Interventions: DRUG: GKT137831|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Post COVID-19 Pulmonary Rehabilitation Program
Status: UNKNOWN
Conditions: Covid19|COVID-19 Respiratory Infection|Lung Diseases|Respiratory Insufficiency|Muscle Weakness|Anxiety Disorder; Mixed With Depression (Mild)
Interventions: OTHER: Pulmonary Rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Pembrolizumab With Chemotherapy in Patients With Advanced Lymphoma (PembroHeme)
Status: WITHDRAWN
Conditions: Lymphoma|Hodgkin's Lymphoma|Non-hodgkin's Lymphoma
Interventions: DRUG: Pembrolizumab|DRUG: Etoposide|DRUG: Ifosfamide|DRUG: Mesna|DRUG: Carboplatin|DRUG: Brentuximab vedotin|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparison of the Metabolic Effects of Fructose, Glucose, High Fructose Corn Syrup and Sucrose at Normal Population Consumed Levels in Adults Aged 20-60 Years Old
Status: COMPLETED
Conditions: Obesity
Interventions: BEHAVIORAL: Dietary Compliance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Bioavailability and Safety of Two Oral Fixed Dose Preparations Containing 18 mg Ivermectin (IVM 18 MG TABLETS, LICONSA S.A., Spain) Versus Reference Dosing (Weight Based) Containing 6 mg Ivermectin (REVECTINA®, Abbott Laboratórios do Brasil Ltda, Brazil)
Status: COMPLETED
Conditions: Helminthiasis
Interventions: DRUG: T1, T2, T3|DRUG: T1,T3,T2|DRUG: T2,T1,T3|DRUG: T2,T3,T1|DRUG: T3,T1,T2|DRUG: T3,T2,T1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Beneficial Effect of Intravenous Magnesium Sulphate in Term Neonates With Hypoxic Ischemic Encephalopathy(HIE)
Status: COMPLETED
Conditions: HIE
Interventions: DRUG: MgSo4
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study in Healthy Women to Test Whether BI 1358894 Influences the Amount of a Contraceptive in the Blood
Status: TERMINATED
Conditions: Healthy
Interventions: DRUG: Yasmin®|DRUG: BI 1358894
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase II, Double-Blind Trial of Recombinant Human Nerve Growth Factor for Treatment of HIV-Associated Sensory Neuropathy
Status: COMPLETED
Conditions: HIV Infections|Peripheral Nervous System Disease
Interventions: DRUG: Nerve Growth Factor, Recombinant Human
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Salvage Chemoradiation Therapy for Recurrence After Radical Surgery or Palliative Surgery in Esophageal Cancer Patients
Status: RECRUITING
Conditions: Esophageal Cancer
Interventions: RADIATION: Involved field irradiation|RADIATION: Elective field irradiation|DRUG: Paclitaxel|DRUG: Platinum|DRUG: PEG-rhG-CSF
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety, Tolerability, and Pharmacodynamics of SDI-118 in Elderly Male and Female Study Participants With Cognitive Decline
Status: TERMINATED
Conditions: Cognitive Decline
Interventions: DRUG: SDI-118|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mifepristone Drug-Drug Interaction Study With CYP3A Inhibitor
Status: COMPLETED
Conditions: Drug Interaction Potentiation|Healthy
Interventions: DRUG: Mifepristone 300 MG|DRUG: Itraconazole 100 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Patient Satisfaction With Novel Double Pants Compared to Conventional Single Pants for Outpatient Colonoscopy
Status: UNKNOWN
Conditions: Colonoscopy
Interventions: PROCEDURE: Pants for colonoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Phase 2 Trial of BMF-219 in Participants With Type 1 Diabetes Mellitus
Status: SUSPENDED
Conditions: Type 1 Diabetes Mellitus
Interventions: DRUG: BMF-219
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intervention to Improve Coping With Negative Emotions in Patients With Psychosis (Feel-Good-Study)
Status: COMPLETED
Conditions: Early Psychosis|Delusions|Emotional Distress|Self Esteem
Interventions: BEHAVIORAL: Feel-Good- Group
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Effect of MCFA and LCFA on Postprandial Appetite and Lipemia
Status: COMPLETED
Conditions: Lipemia
Interventions: DIETARY_SUPPLEMENT: Coconut oil|DIETARY_SUPPLEMENT: Palm oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Absorption, Stable Isotope Appearance and Non-transferrin-bound Iron (NTBI) Profile From NaFeEDTA and Ferrous Sulphate
Status: COMPLETED
Conditions: Iron Deficiency
Interventions: DIETARY_SUPPLEMENT: Porridge fortified with either NaFeEDTA|DIETARY_SUPPLEMENT: FeSO4
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Nonalcoholic Fatty Liver Disease - Intermittent Calorie Restriction (FLICR) Study
Status: COMPLETED
Conditions: Nonalcoholic Fatty Liver|Nonalcoholic Steatohepatitis
Interventions: BEHAVIORAL: Intermittent calorie restriction|BEHAVIORAL: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: World Maternal Antifibrinolytic Trial_2
Status: COMPLETED
Conditions: Intrapartum - Moderate and Severe Anaemia
Interventions: DRUG: Tranexamic Acid|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Adductor Canal Vs Adductor Canal Plus SPANK Block for Postoperative Pain in Knee Arthroplasty Surgery
Status: WITHDRAWN
Conditions: Arthroplasty, Replacement, Knee|Anesthesia, Conduction|Acute Pain
Interventions: PROCEDURE: adductor canal block|PROCEDURE: SPANK|DRUG: Ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Potassium Intake-response Trial to Control Hypertension
Status: TERMINATED
Conditions: Blood Pressure
Interventions: DIETARY_SUPPLEMENT: Potassium Chloride|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Bioequivalence of Eye Drops and Spray Administration of Vigamox
Status: COMPLETED
Conditions: Cataract
Interventions: DRUG: Vigamox - administration in spray form|DRUG: Vigamox eye drops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Allopurinol in Chronic Heart Failure
Status: COMPLETED
Conditions: Chronic Heart Failure|Hyperuricemia
Interventions: DRUG: Allopurinol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Desloratadine Associated With Prednisolone Oral Solution Versus Dexchlorpheniramine Associated With Betamethasone for Cutaneous Rash Treatment
Status: TERMINATED
Conditions: Cutaneous Hypersensitivity
Interventions: DRUG: Desloratadine + Prednisolone|DRUG: Dexchlorpheniramine + Betamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Xuebijing Injection on Sepsis
Status: COMPLETED
Conditions: Sepsis
Interventions: DRUG: Xuebijing Injection|DRUG: normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rituximab in Recurrent IgA Nephropathy
Status: UNKNOWN
Conditions: Recurrent IgA Nephropathy
Interventions: DRUG: Intravenous Rituximab|DRUG: ACEI/ARB and corticosteroids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of PCO2 Gap Algorithm Application on Outcome of High Risk Surgical Patients Undergoing Major Abdominal Surgeries
Status: COMPLETED
Conditions: Major Abdominal Surgeries
Interventions: DEVICE: cv line insertion|DEVICE: Urinary catheter insertion|DEVICE: Arterial line
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Carboplatin-Paclitaxel Adjuvant Chemotherapy in the Treatment of Locally Advanced Cervical Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Locally Advanced Cancer|Cervical Cancer
Interventions: DRUG: Carboplatin-Paclitaxel adjuvant chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Carbetocin Versus Oxytocin in the Prevention of Post Partum Haemorrhage (PPH) in Women Delivered Vaginally With at Least 2 Risk Factors for Atonic PPH: A Randomised Controlled Trial
Status: COMPLETED
Conditions: Delivery
Interventions: DRUG: Carbetocin|DRUG: Oxytocin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Early Warning System for Clinical Deterioration on General Hospital Wards
Status: COMPLETED
Conditions: Escalation of Care|Cardiopulmonary Arrest|Respiratory Arrest|Severe Sepsis|Septic Shock
Interventions: BEHAVIORAL: EWS Nursing Alerts|DEVICE: Wireless Remote Sensor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: PRebiotic to IMprovE Calcium Absorption
Status: COMPLETED
Conditions: Obesity
Interventions: DIETARY_SUPPLEMENT: Prebiotic: soluble corn fiber|DIETARY_SUPPLEMENT: Placebo: maltodextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Effect of Exenatide LAR or Dulaglutide on the Variability of 24-hour Heart Rate and Blood Pressure in Type 2 Diabetes
Status: UNKNOWN
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Exenatide LAR|DRUG: Dulaglutide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Modulation of Insulin Sensitivity by Betaine Upregulation of FGF21
Status: COMPLETED
Conditions: Insulin Sensitivity
Interventions: DIETARY_SUPPLEMENT: Betaine|DIETARY_SUPPLEMENT: Dextrose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Addressing Traumatic Stress Symptoms in Children
Status: ACTIVE_NOT_RECRUITING
Conditions: Violence, Non-accidental|Posttraumatic Stress Disorder|Parent-Child Relations|Assault|Youth
Interventions: BEHAVIORAL: Child and Family Traumatic Stress Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Early Rectal Cancer: Endoscopic Submucosal Dissection or Transanal Endoscopic Microsurgery?
Status: TERMINATED
Conditions: Anal Cancer
Interventions: PROCEDURE: Local excision for early rectal cancer
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Trial of Adjuvant XELOX Chemotherapy and Concurrent Capecitabine and Radiotherapy for Resected Gastric Carcinoma
Status: COMPLETED
Conditions: Gastric Cancer
Interventions: DRUG: Capecitabine|DRUG: Oxaliplatin|RADIATION: Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Umbilical Cord Blood Cell (MC001) Transplant Into Injured Spinal Cord Followed by the Locomotor Training
Status: RECRUITING
Conditions: Spinal Cord Injuries
Interventions: BIOLOGICAL: Umbilical Cord Blood Mononuclear Cell|OTHER: Locomotor Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Interscalene Block and Combined Suprascapular and Axillary Blocks for Proximal Humerus Fracture Surgeries.
Status: RECRUITING
Conditions: Proximal Humerus Fractures
Interventions: PROCEDURE: Patients will receive Supra scapular nerve block and Axillary nerve block.|PROCEDURE: Patients will receive Interscalene block.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Analgesic Effect of Erector Spinae Plane Block After Caesarean Section
Status: COMPLETED
Conditions: Ceserean Section and Postoperative Pain
Interventions: PROCEDURE: Erector Spinae Plane Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Characterization of the Postural Habits of Wheelchair Users Analysis of the Acceptability of International Recommendations in the Prevention of Pressure Sores Risk by Using a Connected Textile Sensor
Status: COMPLETED
Conditions: Duchenne Muscular Dystrophy|Spinal Muscular Atrophy
Interventions: OTHER: Alert "AFNOR 3.6".|OTHER: Alertes " AFNOR 3.6 " et alertes " Guidelines ".
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluation of the Effect of Zinc Citrate Trihydrate Toothpaste on the Oral Plaque Microbiome
Status: COMPLETED
Conditions: Dental Plaque
Interventions: OTHER: ZCT toothpaste|OTHER: Control toothpaste
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Use of Animations Movies to Increase Response in a National Health Survey
Status: COMPLETED
Conditions: Response|Non-response
Interventions: OTHER: Use of small animation movies to increase response in a national health survey
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Desensitization of Nociceptive Afferents by Application of Topical Capsaicin, Trans-cinnamaldehyde and L-menthol
Status: UNKNOWN
Conditions: Pain|Pruritus|Neuropathic Pain|Dermatology/Skin - Other
Interventions: DRUG: Capsaicin|DRUG: Trans-cinnamaldehyde|DRUG: L-Menthol|DRUG: Vehicle patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Abatacept, Ixazomib Citrate, and Dexamethasone in Treating Patients With Multiple Myeloma Resistant to Chemotherapy
Status: ACTIVE_NOT_RECRUITING
Conditions: Recurrent Plasma Cell Myeloma|Refractory Plasma Cell Myeloma
Interventions: BIOLOGICAL: Abatacept|DRUG: Dexamethasone|DRUG: Ixazomib Citrate|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating The Effect Of Ramipril On Urinary Protein Excretion In Renal Transplant Patients Converted To Sirolimus
Status: COMPLETED
Conditions: Kidney Transplant
Interventions: DRUG: ramipril|DRUG: ramipril
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transperineal MRI-TRUS Fusion Guided Prostate Biopsy With vs Without Antibiotic Prophylaxis
Status: COMPLETED
Conditions: Prostate Biopsy|Antibiotic
Interventions: PROCEDURE: Transperineal prostate biopsy with or without antibiotic prophylaxis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Dose-finding Trial of ETC-1002(Bempedoic Acid) in Patients With Hypercholesterolemia
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DRUG: 180mg of ETC-1002(bempedoic acid)|DRUG: 120mg of ETC-1002(bempedoic acid)|DRUG: 60mg of ETC-1002(bempedoic acid)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Usability of the Embrace Seizure Detection Watch in Children and Young Adults With Dravet Syndrome
Status: TERMINATED
Conditions: Dravet Syndrome
Interventions: DRUG: ZX008 (Fenfluramine Hydrochloride)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rives Technique Versus Lichtenstein Repair for Primary Inguinal Hernia
Status: UNKNOWN
Conditions: Primary Inguinal Hernia
Interventions: PROCEDURE: Repair for primary inguinal hernia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I Study to Determine the Optimal Human Challenge Dose for a Norovirus GII.4 Challenge Stock (CIN-1)
Status: WITHDRAWN
Conditions: Gastroenteritis Norovirus
Interventions: BIOLOGICAL: Norovirus GII.4 Challenge Pool CIN-1|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Nicotinamide Riboside in Systolic Heart Failure
Status: COMPLETED
Conditions: Heart Failure, Systolic
Interventions: DIETARY_SUPPLEMENT: nicotinamide riboside|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Isatuximab, Carfilzomib, Pomalidomide, and Dexamethasone for the Treatment of Relapsed or Refractory Multiple Myeloma
Status: RECRUITING
Conditions: Recurrent Multiple Myeloma|Refractory Multiple Myeloma
Interventions: DRUG: Carfilzomib|DRUG: Dexamethasone|BIOLOGICAL: Isatuximab|DRUG: Pomalidomide|PROCEDURE: Bone Marrow Biopsy|PROCEDURE: Bone Marrow Aspiration|PROCEDURE: Skeletal Survey X-Ray|PROCEDURE: Computed Tomography|PROCEDURE: Positron Emission Tomography|PROCEDURE: Magnetic Resonance Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Photodynamic Therapy for Cutibacterium Acnes (C. Acnes) Decolonization of the Shoulder Dermis
Status: UNKNOWN
Conditions: C. Acnes|Phototherapy|Postoperative Infection|Arthroscopic Rotator Cuff Repair|Shoulder Surgery
Interventions: PROCEDURE: Skin Biopsy|DRUG: 5 Aminolevulinic Acid + Phototherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Early Ablation Therapy for the Treatment of Ischemic Ventricular Tachycardia in Patients With Implantable Cardioverter Defibrillators
Status: TERMINATED
Conditions: Ventricular Tachycardia|Ischemic
Interventions: DRUG: Drug Treatment|DEVICE: Catheter Ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Safety and Efficacy of STI-6129 in Patients With Relapsed or Refractory Systemic AL Amyloidosis
Status: RECRUITING
Conditions: Light Chain (AL) Amyloidosis
Interventions: BIOLOGICAL: STI-6129
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dasatinib in Treating Patients With Stage IIIB, Stage IV, or Recurrent Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer|Recurrent Non-small Cell Lung Cancer|Stage IIIB Non-small Cell Lung Cancer|Stage IV Non-small Cell Lung Cancer
Interventions: DRUG: dasatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT