pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Steroids, Azithromycin, Montelukast, and Symbicort (SAMS) for Viral Respiratory Tract Infection Post Allotransplant
Status: TERMINATED
Conditions: Respiratory Tract Infections|Bronchiolitis Obliterans|Cryptogenic Organizing Pneumonia|Lung Diseases, Interstitial
Interventions: DRUG: Prednisone|DRUG: Azithromycin|DRUG: Montelukast|DRUG: Symbicort
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Fecal Microbiota Transplantation for Ulcerative Colitis
Status: UNKNOWN
Conditions: Ulcerative Colitis|Intestinal Bacteria Flora Disturbance|Fecal Microbiota Transplantation
Interventions: OTHER: Fecal Microbiota Transplantation|OTHER: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Cerebellar rTMS on Brain Activity
Status: SUSPENDED
Conditions: The Effects of Cerebellar rTMS on the Brain
Interventions: DEVICE: Cerebellar rTMS|DEVICE: Sham cerebellar rTMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Role of Zamzam Water in Idiopathic Oligohydramnios
Status: UNKNOWN
Conditions: Oligohydramnios
Interventions: DIETARY_SUPPLEMENT: zamzam water|DIETARY_SUPPLEMENT: tap water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Letrozole, Herceptin in Her2neu +, Estrogen Receptor [ER] and/or Progesterone Receptor [PR] Positive, MBC
Status: COMPLETED
Conditions: Metastatic Breast Cancer
Interventions: DRUG: Letrozole|DRUG: Trastuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Open-Label Extension Study of GSK3511294 (Depemokimab) in Participants Who Were Previously Enrolled in 206713 (NCT04719832) or 213744 (NCT04718103)
Status: ACTIVE_NOT_RECRUITING
Conditions: Asthma
Interventions: BIOLOGICAL: GSK3511294 (Depemokimab)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chemoradiation With or Without Nimotuzumab in Treating Esophageal Cancer Patients Who Suffer With Recurrence in Regional Lymph Nodes After Esophagectomy
Status: UNKNOWN
Conditions: Esophageal Squamous Cell Carcinoma
Interventions: BIOLOGICAL: Nimotuzumab|RADIATION: Radiation therapy|RADIATION: radiation therapy|DRUG: chemotherapy|DRUG: chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: JNJ-41443532 Sex, Race, and Age Pharmacokinetic (PK) Study
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Placebo|DRUG: JNJ-41443532
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety and Efficacy of Midline and PICC
Status: COMPLETED
Conditions: Vascular Access Devices|Central Venous Catheter
Interventions: DEVICE: Bard PowerPICC|DEVICE: Bard PowerMidline catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Alcohol Counseling for Telephone Quitline Callers
Status: COMPLETED
Conditions: Smoking|Nicotine Dependence|Alcohol Dependence
Interventions: BEHAVIORAL: Practical Counseling|BEHAVIORAL: Alcohol Intervention Counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Influence of Vitamin C on Post-operative Atrial Fibrillation
Status: UNKNOWN
Conditions: Atrial Fibrillation
Interventions: DIETARY_SUPPLEMENT: Vitamin C|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Effects of Ripasudil in Patients With FED Undergoing Femtosecond Laser Assisted Cataract Surgery
Status: RECRUITING
Conditions: Fuchs' Endothelial Dystrophy|Cataract
Interventions: DRUG: Ripasudil|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy Study on Cenegermin (Oxervate®) vs Vehicle in Severe Sjogren's Dry Eye Disease (PROTEGO-1 Study)
Status: COMPLETED
Conditions: Dry Eye
Interventions: DRUG: Oxervate|OTHER: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pimavanserin for Insomnia in Veterans With PTSD
Status: RECRUITING
Conditions: Post-traumatic Stress Disorder|Insomnia
Interventions: DRUG: pimavanserin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Quadratus Lumborum in Cesarean Section Trial
Status: UNKNOWN
Conditions: Postoperative Analgesia
Interventions: PROCEDURE: Quadratus Lumborum Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Bioequivalence (BE) Study Comparing Azithromycin 250 mg Tablet Manufactured in China and in the United States
Status: COMPLETED
Conditions: Bioequivalence
Interventions: DRUG: Azithromycin Tablet manufactured in China|DRUG: Azithromycin Tablet manufactured in US
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: T4N5 Liposomal Lotion in Preventing The Recurrence of Nonmelanoma Skin Cancer in Patients Who Have Undergone a Kidney Transplant
Status: COMPLETED
Conditions: Actinic Keratosis|Basal Cell Carcinoma of the Skin|Recurrent Skin Cancer|Squamous Cell Carcinoma of the Skin
Interventions: DRUG: liposomal T4N5 lotion|OTHER: placebo|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Infra-orbital Nerve Block for Post Operative Analgesia in Children Undergoing Cleft Lip Surgery.
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: Bupivacaine|DRUG: Ketamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Predictive Nature of the Postoperative CRP on Postoperative Recovery in Patients Undergoing Colorectal Resection (CRP-Track)
Status: COMPLETED
Conditions: Colorectal Postoperative Complication
Interventions: OTHER: C-reactive protein dosage
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: An Evaluation of the Effectiveness of Local Anesthetics Used During Intravenous Catheter Insertion
Status: COMPLETED
Conditions: IV Insertion Pain
Interventions: DRUG: 1% lidocaine|DRUG: bacteriostatic normal saline (BNS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vaccine Biotherapy of Cancer: Autologous Tumor Cells and Dendritic Cells
Status: COMPLETED
Conditions: Metastatic Melanoma
Interventions: BIOLOGICAL: Autologous tumor cells plus dendritic cells|DRUG: GM-CSF
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot-Study With Low-dose hrIL-2 for the Treatment of Systemic Lupus Erythematosus
Status: UNKNOWN
Conditions: Systemic Lupus Erythematosus
Interventions: DRUG: hrIL-2 active|DRUG: hrIL-2 placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Benefits of Peri-surgical Physical Therapy in the Management of III and IV Grades of Pelvic Organ Prolapse
Status: COMPLETED
Conditions: Pelvic Organ Prolapse
Interventions: OTHER: physical therapy|OTHER: surgical treatment|OTHER: behavior therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Phase IIa Study of Multiple Doses of AbGn-168H by iv Infusion in Moderate to Severe Chronic Plaque Psoriasis Patients
Status: COMPLETED
Conditions: Moderate to Severe Chronic Plaque Psoriasis
Interventions: BIOLOGICAL: AbGn-168H|BIOLOGICAL: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pro-miniCHOP-like Regimen for Treatment-naive Elderly Patients
Status: RECRUITING
Conditions: Diffuse Large B Cell Lymphoma
Interventions: DRUG: Rituximab|DRUG: Orelabrutinib|DRUG: Pomalidomide|DRUG: Pro-miniCHOP-like regimen|DRUG: R-miniCHOP-like regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Exercise Intervention Trial to Reduce Symptoms & Improve Clinical Outcomes of Platinum-Based Treatment in Ovarian Cancer Patients
Status: WITHDRAWN
Conditions: Ovarian Carcinoma
Interventions: BEHAVIORAL: Exercise Intervention|OTHER: Laboratory Biomarker Analysis|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Misoprostol Versus Oxytocin for Induction of Labour in Parturients With Spontaneous Rupture of Fetal Membranes at Term
Status: COMPLETED
Conditions: Labor Onset and Length Abnormalities
Interventions: DRUG: Labour Induction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Technique for Assessment of Vocal Cord Movement by C-Mac Videolaryngoscope vs Airway Ultrasound.
Status: COMPLETED
Conditions: Objective Vocal Cord Movement Assessment by C-Mac Videolaryngoscope Vs Airway Ultrasound in Ca Thyroid
Interventions: DEVICE: Active Comparator :C-Mac Videolaryngoscope|DEVICE: Experimental: Airway ultrasound,
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: DIAGNOSTIC
Clinical trial: Pharmacokinetic Study Of Ibuprofen Injection (IVIb) In Healthy Adult Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: IVIb
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Enhancing Behavioral Treatment for Women With Pelvic Floor Disorders
Status: COMPLETED
Conditions: Pelvic Floor Disorders|Anxiety|Urinary Urgency|Urinary Incontinence|Nocturia|Urinary Frequency/Urgency|Lower Urinary Tract Symptoms|Urinary Hesitancy|Urinary Straining
Interventions: BEHAVIORAL: Unified Protocol|BEHAVIORAL: Supportive Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Capecitabine, Oxaliplatin, Bevacizumab and Radiation Therapy in Patients With Biliary Tract and Gallbladder Cancer
Status: COMPLETED
Conditions: Biliary Tract Cancer|Gallbladder Adenocarcinoma
Interventions: DRUG: Capecitabine|DRUG: Oxaliplatin|DRUG: Bevacizumab|PROCEDURE: Radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Ceftaroline Versus a Comparator in Pediatric Subjects With Complicated Community Acquired Pneumonia (CABP)
Status: COMPLETED
Conditions: Infections|Pneumonia
Interventions: DRUG: Ceftaroline fosamil|DRUG: IV Ceftriaxone and Vancomycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Erector Spinae Plane Block Reduces Postoperative Pain Following Laparoscopic Colorectal Operation
Status: RECRUITING
Conditions: Postoperative Pain
Interventions: PROCEDURE: Erector Spinae Plane Block|PROCEDURE: Intravenous fentanyl patient control device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Predictors for Bronchoalveolar Lavage (BAL) Recovery Rate Derived From Quantified Computed Tomography (qCT)
Status: COMPLETED
Conditions: Interstitial Lung Disease|Pneumonia|Malignant Neoplasm
Interventions: PROCEDURE: bronchoalveolar lavage (BAL)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phase III Efficacy and Safety Study of Oleogel-S10 in Epidermolysis Bullosa
Status: COMPLETED
Conditions: Epidermolysis Bullosa
Interventions: DRUG: Oleogel-S10|DRUG: Control gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Single Lumen Needle Without Flushing or Double Lumen Needle With Follicle Flushing in Oocyte Retrieval
Status: COMPLETED
Conditions: Oocyte Retrieval
Interventions: DEVICE: single lumen needle oocyte retrieval|DEVICE: double lumen needle oocyte retrieval
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: A Study to Compare the Immune Response and Safety Elicited by Henogen's Adjuvanted Hepatitis B Vaccine Compared to Aventis Pasteur MSD's Hepatitis B Vaccine in Pre-Dialysis and Dialysis Patients Who Responded to Previous Hepatitis B Vaccination But Lost Antibody.
Status: COMPLETED
Conditions: Hepatitis B
Interventions: BIOLOGICAL: HB-AS02V vaccine|BIOLOGICAL: HBVAXPRO vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety Study of Nebulized Sodium Nitroprusside in Adult Acute Lung Injury
Status: UNKNOWN
Conditions: Acute Lung Injury|Acute Respiratory Distress Syndrome|Sodium Nitroprusside|Hypoxia|Respiratory Failure
Interventions: DRUG: Sodium Nitroprusside
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Efficacy of Ceramic vs Resin Block Endocrown
Status: UNKNOWN
Conditions: Tooth Diseases
Interventions: DEVICE: Resin blocs (Grandio Blocs, VOCO)|DEVICE: Ceramic (Suprinity, VITA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Compassionate Use Protocol for the Treatment of Autoinflammatory Syndromes
Status: NO_LONGER_AVAILABLE
Conditions: Chronic Atypical Neutrophilic Dermatosis With Lipodystrophy and Elevated Temperature (CANDLE)|Juvenile Dermatomyositis (JDM)|Stimulator of Interferon Genes (STING)-Associated Vasculopathy With Onset During Infancy (SAVI)|Aicardi-Goutières Syndrome (AGS)
Interventions: DRUG: Baricitinib
Study Type: EXPANDED_ACCESS
Clinical trial: The Effect of Desensitizing Agents in In-home or In-office Dental Bleaching
Status: COMPLETED
Conditions: Dentin Hypersensitivity
Interventions: OTHER: Dental bleaching|OTHER: Desensitizing therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigating the Neural Correlates of Cognitive Function in Psychosis Patients and Non-Psychiatric Controls With Cannabis Use
Status: RECRUITING
Conditions: Psychotic Disorders|Cannabis Use Disorder|Cannabis Dependence|Cannabis Use|Schizophrenia; Psychosis|Cognitive Dysfunction|Memory Impairment|Neuroimaging
Interventions: BEHAVIORAL: Contingency management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Concentration and Attentional Deficits in POTS and Other Autonomic Neuropathies
Status: COMPLETED
Conditions: Autonomic Failure|Dysautonomia|Cognitive Impairment|Ehlers-Danlos Syndrome|Postural Tachycardia Syndrome|Pure Autonomic Failure
Interventions: PROCEDURE: leg crossing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Pregabalin or Adductor Canal Block on Postoperative Analgesia
Status: COMPLETED
Conditions: Postoperative Pain After Knee Arthroscopy
Interventions: DRUG: pregabalin (lyrica)|DRUG: Placebo oral tablet|DRUG: adductor canal block including bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Study to Evaluate the Efficacy, Safety and Tolerability of Vibegron in Men With Overactive Bladder (OAB) Symptoms on Pharmacological Therapy for Benign Prostatic Hyperplasia (BPH)
Status: COMPLETED
Conditions: Overactive Bladder
Interventions: DRUG: Vibegron|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Brexpiprazole in Patients With Acute Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Placebo|DRUG: Brexpiprazole|DRUG: Quetiapine extended release
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Scapular Mobilization And Strengthening Exercises on Shoulder Function Post Mastectomy
Status: COMPLETED
Conditions: Oncologic Complications|Exercise Therapy|Shoulder Pain|Shoulder Syndrome
Interventions: OTHER: Scapular mobilization and Scapular strengthening exercises|OTHER: Conventional physical therapy program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study of DKN-01 and Gemcitabine/Cisplatin in Patients With Carcinoma to Primary to the Intra- or Extra-Hepatic Biliary System or Gallbladder
Status: COMPLETED
Conditions: Carcinoma of Intrahepatic and Extra-hepatic Biliary System|Carcinoma of Gallbladder|Bile Duct Cancer|Cholangiocarcinoma
Interventions: DRUG: DKN-01|DRUG: gemcitabine|DRUG: cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Safety and Efficacy of NRP104 in Adults With Attention-Deficit Hyperactivity Disorder (ADHD)
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder|Attention Deficit Disorders With Hyperactivity|Attention Deficit Hyperactivity Disorders
Interventions: DRUG: NRP104
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Eccentric Resistance Training Among Individuals With Chronic Heart Failure
Status: RECRUITING
Conditions: Heart Failure
Interventions: OTHER: Eccentric Resistive Training + Aerobic training Group|OTHER: Resistance Training + Aerobic training Group|OTHER: Aerobic training Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Entolimod in Treating Patients With Stage III-IV Squamous Cell Head and Neck Cancer Receiving Cisplatin and Radiation Therapy
Status: WITHDRAWN
Conditions: Mucositis|Recurrent Squamous Cell Carcinoma of the Hypopharynx|Recurrent Squamous Cell Carcinoma of the Larynx|Recurrent Squamous Cell Carcinoma of the Lip and Oral Cavity|Recurrent Squamous Cell Carcinoma of the Nasopharynx|Recurrent Squamous Cell Carcinoma of the Oropharynx|Recurrent Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity|Recurrent Verrucous Carcinoma of the Larynx|Recurrent Verrucous Carcinoma of the Oral Cavity|Stage III Squamous Cell Carcinoma of the Hypopharynx|Stage III Squamous Cell Carcinoma of the Larynx|Stage III Squamous Cell Carcinoma of the Lip and Oral Cavity|Stage III Squamous Cell Carcinoma of the Nasopharynx|Stage III Squamous Cell Carcinoma of the Oropharynx|Stage III Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity|Stage III Verrucous Carcinoma of the Larynx|Stage III Verrucous Carcinoma of the Oral Cavity|Stage IV Squamous Cell Carcinoma of the Hypopharynx|Stage IV Squamous Cell Carcinoma of the Nasopharynx|Stage IVA Squamous Cell Carcinoma of the Larynx|Stage IVA Squamous Cell Carcinoma of the Lip and Oral Cavity|Stage IVA Squamous Cell Carcinoma of the Oropharynx|Stage IVA Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity|Stage IVA Verrucous Carcinoma of the Larynx|Stage IVA Verrucous Carcinoma of the Oral Cavity|Stage IVB Squamous Cell Carcinoma of the Larynx|Stage IVB Squamous Cell Carcinoma of the Lip and Oral Cavity|Stage IVB Squamous Cell Carcinoma of the Oropharynx|Stage IVB Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity|Stage IVB Verrucous Carcinoma of the Larynx|Stage IVB Verrucous Carcinoma of the Oral Cavity|Stage IVC Squamous Cell Carcinoma of the Larynx|Stage IVC Squamous Cell Carcinoma of the Lip and Oral Cavity|Stage IVC Squamous Cell Carcinoma of the Oropharynx|Stage IVC Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity|Stage IVC Verrucous Carcinoma of the Larynx|Stage IVC Verrucous Carcinoma of the Oral Cavity|Tongue Cancer
Interventions: DRUG: entolimod|RADIATION: intensity-modulated radiation therapy|DRUG: cisplatin|OTHER: pharmacological study|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hydroxychloroquine in Colchicine-Resistant Glucocorticoid-Dependent Idiopathic Recurrent Pericarditis
Status: NOT_YET_RECRUITING
Conditions: Pericarditis Idiopathic Recurrent
Interventions: DRUG: Hydroxychloroquine|DRUG: Colchicine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Clinical and Cyto-histological Evaluation of Fractional CO2 Laser Treatment on Genito-Urinary Syndromes of Menopause Related to Vaginal Atrophy
Status: ACTIVE_NOT_RECRUITING
Conditions: Genitourinary Syndrome of Menopause
Interventions: DEVICE: CO2 laser MonaLisa Touch ®
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of 1 Liter PEG With Ascorbate and Sodium Picosulfate / Magnesium Citrate for High Quality Colon Cleansing
Status: UNKNOWN
Conditions: Colonic Diseases
Interventions: DRUG: Polyethylene glycol + ascorbate|DRUG: Sodium picosulfate + magnesium citrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Minimally Invasive Tongue Suture For Obstructive Sleep Apnea
Status: TERMINATED
Conditions: Obstructive Sleep Apnea|Upper Airway Resistance Syndrome
Interventions: PROCEDURE: Tongue Sutures for Obstructive Sleep Apnea
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Carmustine, Etoposide, Cytarabine, Melphalan, and Alemtuzumab Followed by Donor Stem Cell Transplant in Treating Patients With Relapsed or Refractory Hodgkin Lymphoma
Status: UNKNOWN
Conditions: Lymphoma
Interventions: BIOLOGICAL: alemtuzumab|BIOLOGICAL: donor lymphocytes|DRUG: carmustine|DRUG: cyclosporine|DRUG: cytarabine|DRUG: etoposide|DRUG: melphalan|PROCEDURE: allogeneic hematopoietic stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cerebral Responses to Insulin Induced Hypoglycemia
Status: COMPLETED
Conditions: Type 1 Diabetes|Healthy|Hypoglycemia Unawareness
Interventions: OTHER: hypoglycemia (low blood sugar) in MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation of Tolerance, Efficacy and Safety of an Hydrolyzed Formula in Infants With IgE/Non-IgE Mediated CMA.
Status: NOT_YET_RECRUITING
Conditions: Cow's Milk Allergy
Interventions: DIETARY_SUPPLEMENT: Test Formula|DIETARY_SUPPLEMENT: Placebo Formula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Kinesiological Taping and Aerobic Exercise in Women With Primary Dysmenorrhea:
Status: COMPLETED
Conditions: Primary Dysmenorrhea|Kinesics|Aerobic Exercise
Interventions: BEHAVIORAL: Kinesiological taping|BEHAVIORAL: Aerobic exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Blood Sugar Lowering Effect of Biphasic Insulin Aspart 30 and Insulin Glargine Both Combined With Metformin and Glimepiride in Chinese and Japanese Subjects With Type 2 Diabetes New to Insulin Treatment
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: biphasic insulin aspart 30|DRUG: metformin|DRUG: glimepiride|DRUG: insulin glargine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reducing Perioperative Oxidative Stress to Prevent Postoperative Chronic Pain Following Total Knee Arthroplasty
Status: NOT_YET_RECRUITING
Conditions: Osteoarthritis, Knee|Total Knee Arthroplasty|Chronic Postsurgical Pain
Interventions: DRUG: GlyNAC (combination of glycine and n-acetylcysteine)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Parathyroid Allotransplantation in Medically Refractory Hypoparathyroidism
Status: RECRUITING
Conditions: Hypoparathyroidism
Interventions: PROCEDURE: Parathyroid Allotransplant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: QUILT-3.025: A Phase 2 Study of AMG 479 in Relapsed or Refractory Ewing's Family Tumor and Desmoplastic Small Round Cell Tumors
Status: COMPLETED
Conditions: Askin's Tumors|Desmoplastic Small Round Cell Tumors|Estraosseous Ewing's Tumor|Ewing's Family Tumor|Ewing's Sarcoma|Primitive Neuroectodermal Tumors (PNETs)|Sarcoma
Interventions: DRUG: AMG 479
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intra- Versus Extraarticular Injection of Ropivacaine in Total Knee Arthroplasty
Status: UNKNOWN
Conditions: Pain, Postoperative
Interventions: DRUG: intraarticular injection with ropivacaine|DRUG: extraarticular injection with ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Aliskiren, Irbesartan, and the Combination in Hypertensive Patients With Type 2 Diabetes and Diabetic Nephropathy
Status: COMPLETED
Conditions: Diabetes Type 2
Interventions: DRUG: Aliskiren
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Effectiveness of Rivaroxaban (Xarelto) for Prevention of Stroke and Systemic Embolism in Indian Patients With Non-valvular Atrial Fibrillation (NVAF)
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-valvular Atrial Fibrillation (NVAF)
Interventions: DRUG: Rivaroxaban (Xarelto,Bay 59-7939)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Tucidinostat Combined With Metronomic Capecitabine and Endocrine Therapy for Advanced HR-positive, HER2-negative Breast Cancer After CDK4/6 Inhibitor.
Status: RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Tucidinostat|DRUG: Capecitabine|DRUG: Endocrine Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Berberine Chloride in Preventing Colorectal Cancer in Patients With Ulcerative Colitis in Remission
Status: COMPLETED
Conditions: Ulcerative Colitis
Interventions: DRUG: Berberine Chloride|OTHER: Laboratory Biomarker Analysis|OTHER: Placebo Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Randomised Trial of Eutectic Mixture of Local Anaesthetics Cream and Oral Sucrose Solution for Venepuncture
Status: COMPLETED
Conditions: Pain
Interventions: PROCEDURE: venepuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Vitamin A Supplementation for Modulation of Mycobacterium Tuberculosis Immune Responses in Latent Tuberculosis
Status: WITHDRAWN
Conditions: Latent Tuberculosis Infection
Interventions: DRUG: Vitamin A|DRUG: Vitamin A placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Telehealth in Improving Quality of Life in Patients During Post Radiation Therapy Visits
Status: COMPLETED
Conditions: Malignant Neoplasm
Interventions: OTHER: Telemedicine|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Efficacy and Safety of Luo-Fu-Shan Plaster in Patients With Rheumatoid Arthritis
Status: UNKNOWN
Conditions: Arthritis, Rheumatoid
Interventions: DRUG: Luo-Fu-Shan Plaster|DRUG: The placebo 10g
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Sedation During Spinal Anesthesia
Status: COMPLETED
Conditions: Sedation During Spinal Anesthesia
Interventions: DRUG: Ketamine|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Acute Coronary Syndrome Sri Lanka Audit Project
Status: WITHDRAWN
Conditions: Acute Coronary Syndrome|Unstable Angina|Non ST Elevation Myocardial Infarction|ST Elevation Myocardial Infarction
Interventions: DRUG: aspirin, clopidogrel, statin, enoxaparin, streptokinase
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effectiveness of Calcium Silicate and Sodium Fluoride Nanoparticles in The Management of Dentin Hypersensitivity
Status: NOT_YET_RECRUITING
Conditions: Dentin Hypersensitivity
Interventions: OTHER: toothpaste
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Implementing Effective, Collaborative Care for Schizophrenia (EQUIP-2)
Status: COMPLETED
Conditions: Schizophrenia|Chronic Illness|Weight Gain|Psychotic Disorder
Interventions: BEHAVIORAL: Collaborative Chronic Illness Care Model
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Sleeve Gastrectomy With Reestablishment of the Acute Angle of His (SG-REACH) in Obese Patients
Status: RECRUITING
Conditions: Gastroesophageal Reflux Disease|Excessive Weight Loss|Total Weight Loss|Sleeve Gastrectomy|Angle of His
Interventions: PROCEDURE: reestablishment of the acute angle of His|PROCEDURE: sleeve gastrectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Continuous Bloodsugar Monitoring System With a Sensor Compared to Fingerstick Bloodsugar Monitoring
Status: NOT_YET_RECRUITING
Conditions: Diabetes Mellitus
Interventions: DEVICE: Abott FreeStyle Libre System 2|DEVICE: Abott Freestyle Libre Pro
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Fixed-doses of Antihypertensive and Statin Drugs
Status: WITHDRAWN
Conditions: Hypertension|Dyslipidemia
Interventions: DRUG: Viena II 160/10|DRUG: Viena II 190/10|DRUG: Viena II 160/12|DRUG: Viena II 190/12
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: PROTeIn-rich Meals to Control Glucose
Status: RECRUITING
Conditions: Overweight|Obesity|Prediabetes|Type 2 Diabetes
Interventions: OTHER: Diet with specific macronutrient composition.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of a Pre-operative Internet-based Educational Video on Post Operative Opioid Consumption
Status: RECRUITING
Conditions: Patient Empowerment
Interventions: OTHER: Opioid Counseling and Pain Coping Skills Video
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of Bifidobacterium Quadruple Live Tablets in Patients With T2DM and Constipation
Status: UNKNOWN
Conditions: Type 2 Diabetes Mellitus With Complication
Interventions: DRUG: Bifidobacterium, Lactobacillus, Enterococcus and Bacillus Cereus Tablets, Live|DRUG: Siliankang simulating tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fixed Low-dose Heparin Versus Standard Adjusted-dose Heparin Infusion in Adults Receiving Venovenous ECMO With a Heparin Bonded Circuit.
Status: WITHDRAWN
Conditions: Acute Respiratory Failure|Extracorporeal Membrane Oxygenation Complication|Bleeding
Interventions: DRUG: HEP-IV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Long-Term Analysis of DImethyl Fumarate, to Slow the Growth of Areas of Geographic Atrophy
Status: RECRUITING
Conditions: Age-related Macular Degeneration (AMD)
Interventions: DRUG: Dimethyl Fumarate (TECFIDERA™)|OTHER: No active : no treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Investigational Anti-Influenza Immune Plasma in Treating Influenza
Status: COMPLETED
Conditions: Influenza A|Influenza B
Interventions: BIOLOGICAL: Anti-Influenza Immune Plasma|DRUG: Standard Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial Readiness and Endpoint Assessment in LGMD R1
Status: RECRUITING
Conditions: Calpain-3 Deficiency Limb Girdle Muscular Dystrophy Type 2A|Limb Girdle Muscular Dystrophy|Limb Girdle Muscular Dystrophy Type R1|LGMD2A
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of Indocyanine Green-guided Systematic Pelvic Lymphadenectomy in Endometrial and Cervical Cancer
Status: COMPLETED
Conditions: Endometrial Cancer|Cervical Cancer
Interventions: PROCEDURE: Indocyanine green-guided systematic pelvic lymphadenectomy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Smartphone-based Intervention for Diabetes Prevention in Overweight Chinese Adults With Pre-diabetes
Status: UNKNOWN
Conditions: Pre-diabetes
Interventions: BEHAVIORAL: Digital diabetes prevention app intervention|BEHAVIORAL: Digital weight loss tracking app intervention|BEHAVIORAL: Wait-list control (usual care)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study on the Long-term Efficacy, Safety and Persistence of Immune Response of a Vaccine Against Herpes Zoster in Older Adults
Status: ACTIVE_NOT_RECRUITING
Conditions: Herpes Zoster
Interventions: BIOLOGICAL: HZ/su vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Feasibility of a Novel Resistance Exercise in Individuals With Osteoporosis
Status: NOT_YET_RECRUITING
Conditions: Osteopenia|Osteoporosis|Postmenopausal Osteoporosis|Sarcopenia
Interventions: OTHER: Exercise training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Modulation of Upper Limb Spasticity Post-Stroke
Status: COMPLETED
Conditions: Spasticity as Sequela of Stroke|Spastic Hemiplegia|Upper Extremity Dysfunction
Interventions: DEVICE: Virtual reality-based training equipment.|OTHER: Traditional physical therapy program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Dryness in a Silicone Hydrogel Daily Disposable Contact Lens
Status: COMPLETED
Conditions: Visual Acuity
Interventions: DEVICE: ACUVUE Oasys 1-Day|DEVICE: Habitual Lens
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Multilevel System Intervention Based on Information Platform to Reduce Ischemic Stroke Recurrence Rate
Status: NOT_YET_RECRUITING
Conditions: Acute Ischemic Stroke|Stroke Recrudescence|Quality Improvement
Interventions: BEHAVIORAL: multilevel system intervention based on information platform
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Various Methods Used to Identify the Proximal Humerus Intraosseous Vascular Access Site
Status: UNKNOWN
Conditions: Proximal Humerus Intraosseous Vascular Access
Interventions: PROCEDURE: Proximal Humerus Intraosseous Vascular Access
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: The Influence of Whole-body Vibration Training on Postural Stability in People With Generalized Joint Hypermobility
Status: COMPLETED
Conditions: Hypermobility, Joint
Interventions: DEVICE: Galileo Med35
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Intestinal & Multivisceral Transplantation for Unresectable Mucinous Carcinoma Peritonei (TRANSCAPE)
Status: NOT_YET_RECRUITING
Conditions: Secondary Malignant Neoplasm of Retroperitoneum|Secondary Malignant Neoplasm of Peritoneum|Pseudomyxoma Peritonei
Interventions: PROCEDURE: Intestinal, Multivisceral or Modified Multivisceral Transplantation|DRUG: Alemtuzumab|DRUG: Tacrolimus|DRUG: Sirolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: My-HyperCVAD in the Treatment of Relapsed Refractory Adult Acute Lymphoid Leukemia
Status: UNKNOWN
Conditions: Lymphoid Leukemia
Interventions: DRUG: doxorubicin liposomal
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects and Safety of 5% Lifitegrast Ophthalmic Solution in Subjects With Dry Eye Disease in Ocular Graft-versus-Host Disease
Status: COMPLETED
Conditions: Graft-versus-host-disease|Ocular Graft-versus-host Disease
Interventions: DRUG: Lifitegrast 5% Ophthalmic Solution|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Rehabilitation Protocol in Patients With Shortened Posterior Leg Muscles
Status: RECRUITING
Conditions: Equinus Deformity of Foot|Gastrocnemius Equinus|Contracture
Interventions: PROCEDURE: Specific protocol of rehabilitation exercise|PROCEDURE: Short gastrocnemius surgery.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Self-expandable Esophageal Stent Versus Balloon Tamponade in Refractory Esophageal Variceal Bleeding.
Status: COMPLETED
Conditions: Esophageal Varices|Bleeding|Cirrhosis
Interventions: DEVICE: Stent|DEVICE: Tamponade
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Liposomal Irinotecan and Capecitabine Plus Bevacizumab as Second-line Therapy in Metastatic Colorectal Cancer
Status: NOT_YET_RECRUITING
Conditions: Colorectal Cancer
Interventions: DRUG: Liposomal irinotecan|DRUG: Capecitabine|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Changes in Cardiac Functions in Patients Treated With Parathyroidectomy for Secondary Hyperparathyroidism
Status: COMPLETED
Conditions: Secondary Hyperparathyroidism|Myocardial Dysfunction
Interventions: PROCEDURE: total parathyroidectomy (group 1) and those who underwent subtotal parathyroidectomy (group 2)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study To Determine The Pharmacokinetics Of Sulfasalazine In Children With Juvenile Idiopathic Arthritis
Status: TERMINATED
Conditions: Arthritis, Juvenile Rheumatoid
Interventions: DRUG: Sulfasalazine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate IBI112 in the Treatment of Moderate to Severe Active Ulcerative Colitis
Status: ACTIVE_NOT_RECRUITING
Conditions: Ulcerative Colitis (UC)
Interventions: DRUG: Period 1 IBI112 Placebo|DRUG: Period 2 IBI112 dose 3|DRUG: Period 1 IBI112 dose 1|DRUG: Period 1 IBI112 dose 2|DRUG: Period 2 IBI112 dose 4|DRUG: Period 2 IBI112 Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Indigotindisulfonate Sodium Injection, USP as an Aid in the Determination of Ureteral Patency
Status: RECRUITING
Conditions: Ureter Injury
Interventions: DRUG: Indigotindisulfonate sodium 0.8%|OTHER: Saline injection 0.9%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy and Safety of G-CSF in Patients With Severe Alcoholic Hepatitis With Null or Partial Response to Steroid
Status: TERMINATED
Conditions: Alcoholic Hepatitis
Interventions: DRUG: G-CSF (Filgrastim injection)|DRUG: steroid|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Improving Medication Adherence Through Graphically Enhanced Interventions in Acute Coronary Syndromes
Status: COMPLETED
Conditions: Acute Coronary Syndrome (ACS)
Interventions: BEHAVIORAL: Health literacy intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy Plus Radiation Therapy With or Without Fluorouracil in Treating Patients With Cancer of the Esophagus or Stomach
Status: COMPLETED
Conditions: Esophageal Cancer|Gastric Cancer
Interventions: BIOLOGICAL: filgrastim|DRUG: cisplatin|DRUG: fluorouracil|DRUG: paclitaxel|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: The Effect of a Plant-based Diet on the Active Rheumatoid Arthritis Activity.
Status: RECRUITING
Conditions: Rheumatoid Arthritis|Diet, Healthy|Inflammatory Response
Interventions: BEHAVIORAL: Plant-based diet for 14 days in patients with rheumatoid arthritis.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Long-term Elobixibat for Chronic Constipation
Status: RECRUITING
Conditions: Chronic Constipation
Interventions: DRUG: Elobixibat 10mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Safety and Efficacy of Tizanidine Hydrochloride Capsules Versus Zanaflex® (Tizanidine Hydrochloride Tablets) Taken While in the Fed State (Just After a Meal) and in the Fasted State (Before a Meal) in Patients With Moderate to Severe Spasticity.
Status: COMPLETED
Conditions: Multiple Sclerosis|Muscle Spasticity|Spinal Cord Injury|Stroke
Interventions: DRUG: tizanidine hydrochloride capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Effectiveness Study of Chemotherapy and Ziv-aflibercept to Treat Metastatic Colorectal Cancer
Status: WITHDRAWN
Conditions: Colorectal Cancer|Metastatic Colorectal Cancer
Interventions: DRUG: 5-FU|DRUG: LV|DRUG: ziv-aflibercept|DRUG: mFOLFOX6
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT