pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Comparison of Neutral Protamine Hagedorn (NPH) and Lantus Based Insulin Regimen in the Management of Hypoglycemia in the Hospitalized Patients in Noncritical Care Setting
Status: TERMINATED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: NPH and regular insulin|DRUG: glargine and humalog
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Efficacy, Safety, and Pharmacokinetics Study of Beloranib in Obese Subjects With Hypothalamic Injury
Status: COMPLETED
Conditions: Obesity|Over-weight|Hypothalamic Injury|Craniopharyngioma
Interventions: DRUG: ZGN-440 sterile diluent|DRUG: ZGN-440 for injectable suspension
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Does Placebo Information Affect the Trial Outcomes and Participant Blinding?
Status: COMPLETED
Conditions: Muscle Soreness
Interventions: DEVICE: acupuncture|DEVICE: Park Sham Needle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The GORE Viabahn Endoprosthesis for the Treatment of Venous Occlusions and Stenoses
Status: TERMINATED
Conditions: Venous Thrombosis
Interventions: DEVICE: Gore Viabahn Heparin Coated Stent
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Flax in Yogurt on Blood Cyanide Levels
Status: NOT_YET_RECRUITING
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: 0 g Flax|DIETARY_SUPPLEMENT: 40 g whole ground flaxseed|DIETARY_SUPPLEMENT: 40 g roasted then ground whole flaxseed|DIETARY_SUPPLEMENT: 40 g of whole intact flaxseeds|DIETARY_SUPPLEMENT: 28 g flax hulls
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Randomized, Double-blind, Placebo-controlled Phase II Clinical Study to Evaluate the Safety, Tolerability, Efficacy, and Pharmacokinetic Profile of Genakumab Injection in Patients With Connective Tissue Disease-associated Interstitial Lung Disease
Status: NOT_YET_RECRUITING
Conditions: Systemic Sclerosis Associated Interstitial Lung Disease|Rheumatoid Arthritis Associated Interstitial Lung Disease (RA-ILD)|Systemic Sclerosis Associated Interstitial Lung Disease (SSc-ILD)
Interventions: DRUG: GenSci048|DRUG: GenSci048 placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Effects of Endothelin Receptor Antagonist on Ischemic Kidney Injury During Nephron Sparing Surgery
Status: UNKNOWN
Conditions: Kidney Failure, Acute
Interventions: DRUG: Ambrisentan 10 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Intra-articular Administration of Med Device Made of Biological Vegetal Matrix for the Treatment of Knee Osteoarthritis
Status: RECRUITING
Conditions: the Treatment of Knee Osteoarthritis
Interventions: DEVICE: Medical Device Iniettabile Ginocchio
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety of Meningococcal (A, C, Y and W135) Conjugate Vaccine
Status: COMPLETED
Conditions: Meningitis
Interventions: BIOLOGICAL: MCV-ACYW135 Vaccine Group|BIOLOGICAL: MPV-ACYW135 Vaccine Group|BIOLOGICAL: MPV-A Vaccine Group|BIOLOGICAL: MCV-AC Vaccine Group|BIOLOGICAL: Hib Vaccine Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Long-acting Beta Agonist Step Down Study
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Fluticasone/Salmeterol Diskus|DRUG: Fluticasone/Salmeterol Diskus|DRUG: Fluticasone Diskus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dose-escalating Safety and Preliminary Efficacy of DaxibotulinumtoxinA for Injection in Cervical Dystonia
Status: COMPLETED
Conditions: Torticollis (Spasmodic)
Interventions: BIOLOGICAL: DaxibotulinumtoxinA
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Study of Vandetanib in Individuals With Kidney Cancer
Status: COMPLETED
Conditions: Renal Cancer|Von Hippel Lindau
Interventions: DRUG: ZACTIMA (Vandetanib) (ZD6474)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Measurable Residual Disease Assessment of Cells With Leukemic Stem Cells Associated Phenotype in Patients With Myelodysplastic Syndrome: a Multi-center, Prospective Clinical Study
Status: NOT_YET_RECRUITING
Conditions: Myelodysplastic Syndromes
Interventions: OTHER: Multiparametric Flow Cytometry for the detection of Myelodysplastic syndromes with Measurable residual disease
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: NGS-Based Assay of Blood Samples of Sepsis Patients for Rapid Bacterial Identification
Status: COMPLETED
Conditions: Pneumonia|Acute Pyelonephritis|Bacteremia|Biliary Tract Infection
Interventions: DIAGNOSTIC_TEST: NGS-based assay for bacterial identification
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Use of Navigated Transcranial Magnetic Stimulation (nTMS) in Generated Motor and Language Mapping to Evaluate Brain Recovery Following Surgery
Status: WITHDRAWN
Conditions: Brain Tumor
Interventions: PROCEDURE: Motor Mapping|PROCEDURE: Speech Mapping
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Single Coil Defibrillation Leads for Internal Cardioversion of Atrial Fibrillation
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: PROCEDURE: Internal Cardioversion|PROCEDURE: External Cardioversion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Core Stabilization Exercise Plus Kinesio Taping in Woman With Fibromyalgia
Status: UNKNOWN
Conditions: Fibromyalgia|Exercise|Rheumatic Diseases
Interventions: OTHER: Core stabilization exercise group|OTHER: Core stabilization exercise plus kinesio taping group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Mackenzie's Mission: The Australian Reproductive Carrier Screening Project
Status: ACTIVE_NOT_RECRUITING
Conditions: X-Linked Genetic Diseases|Autosomal Recessive Disorder
Interventions: OTHER: Reproductive Genetic Carrier Screening
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Pilot Evaluation of Two Multipurpose Solutions in Regards to Corneal Staining
Status: COMPLETED
Conditions: Corneal Staining
Interventions: DRUG: sodium citrate, sodium chloride, sodium borate, propylene glycol. citrate, tetronic 1304, AMP 95
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose:
Clinical trial: Safety and Efficacy of Adding Intravenous N-acetyl Cysteine in Colon Surgeries
Status: COMPLETED
Conditions: Systemic Inflammatory Response Syndrome
Interventions: DRUG: N Acetyl L Cysteine|OTHER: dextrose 5%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of Penpulimab and Anlotinib Plus Nab-paclitaxel and Gemcitabine for Metastatic Pancreatic Cancer.
Status: COMPLETED
Conditions: Pancreatic Neoplasms
Interventions: DRUG: Penpulimab|DRUG: Anlotinib|DRUG: Nab paclitaxel|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CONVERT: Neoadjuvant Chemotherapy Alone Versus Preoperative Chemoradiation for Locally Advanced Rectal Cancer Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Rectal Neoplasms
Interventions: DRUG: Oxaliplatin|DRUG: capecitabine|RADIATION: Radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Distress Tolerance and HIV Prevention With XR-NTX Initiation in Opioid Dependence
Status: COMPLETED
Conditions: Opiate Dependence|Sexually Transmitted Diseases|HIV
Interventions: BEHAVIORAL: Acceptance and Commitment Therapy|BEHAVIORAL: Information Motivation Behavioral Model
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Extension From Weekly to Once Every Other Week Darbepoetin Alfa Administration in Subjects With Chronic Kidney Disease Receiving Dialysis
Status: COMPLETED
Conditions: Chronic Kidney Disease
Interventions: DRUG: Darbepoetin Alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Exercise on Fructose-induced Postprandial Lipemia
Status: COMPLETED
Conditions: Sedentary Lifestyle|Dyslipidemias|Lipid Metabolism Disorders|Carbohydrate Inducible Hyperlipemia
Interventions: DIETARY_SUPPLEMENT: FRUCTOSE|DIETARY_SUPPLEMENT: DEXTROSE|DIETARY_SUPPLEMENT: EXERCISE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Sahastara Remedy Extract Capsule in Primary Osteoarthritis of Clinical Trial Phase II
Status: UNKNOWN
Conditions: Osteoarthritis
Interventions: DRUG: Sahastara remedy extract|DRUG: Diclofenac
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of Recombinant Anti-HER2 Humanized Monoclonal Antibody for Injection
Status: UNKNOWN
Conditions: HER2-positive Breast Cancer
Interventions: BIOLOGICAL: GB221,2 mg/kg|BIOLOGICAL: GB221,6 mg/kg|BIOLOGICAL: Herceptin,6 mg/kg|BIOLOGICAL: GB221,8mg/kg|BIOLOGICAL: GB221:2mg/kg and Capecitabi:1000mg/kg|BIOLOGICAL: Herceptin:2mg/kg and Capecitabin:1000mg/kg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Kinesio® Taping in Total Knee Replacement Surgery
Status: COMPLETED
Conditions: Knee Osteoarthritis|Post-Surgical Complication
Interventions: OTHER: Sterile Kinesio Taping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Panitumumab and RAS, Diagnostically-useful Gene Mutation for mCRC
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: oxaliplatin (OXA), levofolinate calcium (l-LV), 5-FU, panitumumab|DRUG: oxaliplatin (OXA), levofolinate calcium (l-LV), 5-FU, bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose-escalating Safety Study of ISIS 301012 in Homozygous Familial Hypercholesterolemia Subjects on Lipid Lowering Therapy
Status: COMPLETED
Conditions: Hypercholesterolemia, Familial
Interventions: DRUG: ISIS 301012|DRUG: ISIS 301012|DRUG: ISIS 301012|DRUG: ISIS 301012
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Validation of a New Automatic Bi-level Algorithm in the Treatment of Sleep-disordered Breathing
Status: COMPLETED
Conditions: Obstructive Sleep Apnea
Interventions: DEVICE: CPAP treatment with subsequent Bi-Level-APAP treatment|DEVICE: Bi-Level-APAP treatment with subsequent CPAP treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pain in America: A Randomized Controlled Trial
Status: TERMINATED
Conditions: Orthopaedic Related Pain (Musculoskeletal Pain)
Interventions: BEHAVIORAL: Control|BEHAVIORAL: Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cranberry Proanthocyanidins for Modification of Intestinal E. Coli Flora and Prevention of Urinary Tract Infections in UTI-Susceptible Women
Status: COMPLETED
Conditions: Urinary Tract Infection
Interventions: OTHER: Sweetened, dried cranberries|OTHER: Strawberry Fruit Pieces|OTHER: Sweetened, dried cranberries|OTHER: Sweetened, dried cranberries|OTHER: Strawberry Fruit Pieces|OTHER: Observation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Assessment of the Impact of Clinical Pharmacogenomics on Real and Potential Medication Use in Veterans
Status: WITHDRAWN
Conditions: Pharmacogenetics|Depressive Disorder, Major|Medication Therapy Management
Interventions: OTHER: Pharmacogenomic Screening
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Dexmedetomidine or Dexmedetomidine Combined With Dexamethasone on Postoperative Nausea and Vomiting in Breast Cancer
Status: COMPLETED
Conditions: Postoperative Nausea and Vomiting
Interventions: DRUG: Dexmedetomidine|DRUG: Dexmedetomidine and dexamethasone|DRUG: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: MRI Targeted Focal Laser Thermal Therapy of Biopsy Confirmed Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: PROCEDURE: MRI Targeted Focal Thermal Therapy of Prostate Cancer
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Tasigna (Nilotinib) 400 mg Twice Daily Alone or With Gleevec (Imatinib Mesylate) 400 mg Daily for Patients With Advanced Gastrointestinal Stromal Tumor (GIST)
Status: TERMINATED
Conditions: GIST|Metastatic Disease
Interventions: DRUG: Nilotinib|DRUG: Nilotinib with Imatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Techniques for Lung Deflation With Arndt® Blocker
Status: COMPLETED
Conditions: Spontaneous Pneumothorax
Interventions: OTHER: Disconnection group|OTHER: Bronchial Suction group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Turmeric on Pruritus in Hemodialysis Patients
Status: COMPLETED
Conditions: End Stage Renal Failure
Interventions: DRUG: turmeric|DRUG: placebo|DRUG: turmeric
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Properties of Idalopirdine (Lu AE58054) in Subjects With and Without Impaired Kidney Function
Status: COMPLETED
Conditions: Alzheimer Disease
Interventions: DRUG: Idalopirdine (Lu AE58054) 60 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Videolaryngoscopes (C-MAC vs Airtraq) for Awake Intubation
Status: COMPLETED
Conditions: Intubation
Interventions: DEVICE: C-MAC videolaryngoscope|DEVICE: Airtraq videolaryngoscope.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Energy Expenditure From ECAL Indirect Calorimeter in a Multicomponent Weight Management Service
Status: COMPLETED
Conditions: Obesity|Severe Obesity|Sleep Apnoea
Interventions: DEVICE: ECAL Indirect Calorimeter|BEHAVIORAL: Diet, exercise & behaviour modification therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Study of Subcutaneous Tocilizumab as Monotherapy and/or in Combination With Non-Biologic Disease Modifying Anti-Rheumatic Drugs (DMARDs) in Participants With Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Azathioprine|DRUG: Chloroquine|DRUG: Hydroxychloroquine|DRUG: Leflunomide|DRUG: Methotrexate|DRUG: Sulfasalazine|DRUG: Tocilizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Prevalence Of Small Airways Dysfunction In Asthma Patients And The Impact On The Asthma Control
Status: UNKNOWN
Conditions: Asthma|Small Airway Disease
Interventions: DIAGNOSTIC_TEST: Impulse oscillometry|DIAGNOSTIC_TEST: Spirometric pulmonary function test|DIAGNOSTIC_TEST: Fractional exhaled nitric oxide (FENO) test|DIAGNOSTIC_TEST: Thorax Computed Tomography|DIAGNOSTIC_TEST: Blood eosinophil level|OTHER: Asthma control test|OTHER: Asthma quality of life scale|DIAGNOSTIC_TEST: Chest X Ray
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of SHR-1210 in Combination With Apatinib or Chemotherapy in Subjects With Advanced PLC or BTC
Status: COMPLETED
Conditions: Advanced Primary Liver Cancer|Advanced Biliary Tract Carcinoma
Interventions: BIOLOGICAL: SHR-1210|DRUG: Apatinib|DRUG: FOLFOX4|DRUG: GEMOX
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Impact of Vaginal Intercourse on Pregnancy Rates After Frozen Embryo Transfer
Status: UNKNOWN
Conditions: Infertility|Pregnancy Related|IVF
Interventions: BEHAVIORAL: Vaginal unprotected intercourse
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Does the Preoperative Midazolam Dose Affect Postoperative Pain?
Status: UNKNOWN
Conditions: Pain, Postoperative
Interventions: DRUG: Midazolam Injectable Solution|OTHER: Normal saline|PROCEDURE: Spinal anesthesia|PROCEDURE: Surgery|DRUG: Postoperative analgesia|DRUG: Rescue analgesia|DRUG: Wound infiltration|DRUG: Analgesia at home
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Blood Volume Assessment in COVID-19 and Bacterial Sepsis
Status: COMPLETED
Conditions: Covid19|Acute Respiratory Distress Syndrome|Bacterial Sepsis|Bacterial Infections
Interventions: DEVICE: BVA-100|DEVICE: Transpulmonary Thermodilution (TPTD)|DEVICE: Sublingual Microcirculation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Single-arm Trial to Evaluate the Role of the Immune Response to Talimogene Laherparepvec in Unresected Melanoma
Status: COMPLETED
Conditions: Unresected Stage IIIb to IVM1c Melanoma
Interventions: DRUG: Talimogene Laherparepvec
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Boosting The Intervention Effect of Negative Memory Through tACS Stimulation
Status: NOT_YET_RECRUITING
Conditions: Seizures
Interventions: DEVICE: Active tACS Device|DEVICE: Sham tACS Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: RE-ELECT. Dabigatran vs Warfarin in AF Patients With T2DM and CKD
Status: UNKNOWN
Conditions: Atrial Fibrillation|T2DM (Type 2 Diabetes Mellitus)|Chronic Kidney Diseases
Interventions: DRUG: Dabigatran Etexilate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Randomized Phase III-Study in Stage IIIb and IV Non-Small-Cell Lung Cancer. Sequential Single-Agent vs. Double-Agent vs. Triple-Agent Therapy.
Status: COMPLETED
Conditions: Non-Small-Cell Lung Carcinoma
Interventions: DRUG: Gemcitabine|DRUG: Navelbine|DRUG: Carboplatin|DRUG: Cisplatin|DRUG: Mitomycin|DRUG: Ifosfamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Amivantamab and Lazertinib in Combination With Platinum-Based Chemotherapy Compared With Platinum-Based Chemotherapy in Patients With Epidermal Growth Factor Receptor (EGFR)-Mutated Locally Advanced or Metastatic Non- Small Cell Lung Cancer After Osimertinib Failure
Status: ACTIVE_NOT_RECRUITING
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: Lazertinib|DRUG: Amivantamab|DRUG: Pemetrexed|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Laser Therapy for Perioral Dermatitis
Status: WITHDRAWN
Conditions: Perioral Dermatitis
Interventions: DEVICE: Pulse laser dye therapy (Device name: Candela Family of Pulsed Dye Laser Systems. 501k Number: K050673.)|DRUG: Clindamycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Efficacy of Topical Ophthalmic Steroids in a Modified Conjunctival Allergen Challenge (CAC) Model
Status: COMPLETED
Conditions: Allergic Conjunctivitis
Interventions: DRUG: Prednisolone Sodium Phosphate Ophthalmic Solution 1%|DRUG: Tears Naturale II Ophthalmic Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of 17 Alpha-hydroxyprogesterones Caproate for the Prevention of Preterm Delivery
Status: COMPLETED
Conditions: Preterm Delivery
Interventions: DRUG: 17 alpha-hydroxyprogesterones caproate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Laser Therapy for Onychomycosis in Patients Wih Diabetes at Risk for Diabetic Foot Complications
Status: COMPLETED
Conditions: Onychomycosis
Interventions: DEVICE: Nd:YAG laser pulse therapy|DEVICE: Sham procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vaginal Versus Intramuscular Progesterone for the Prevention of Recurrent Preterm Birth
Status: COMPLETED
Conditions: Premature Birth
Interventions: DRUG: Vaginal Progesterone|DRUG: Intramuscular Progesterone (17 alpha hydroxprogesterone caproate)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Efficacy and Safety of Oral Azacitidine Plus Best Supportive Care Versus Placebo and Best Supportive Care in Subjects With Red Blood Cell (RBC) Transfusion-Dependent Anemia and Thrombocytopenia Due to International Prognostic Scoring System (IPSS) Low Risk Myelodysplastic Syndrome (MDS)
Status: COMPLETED
Conditions: Myelodysplastic Syndrome
Interventions: DRUG: Oral Azacitidine|DRUG: Placebo|OTHER: Best Supportiv Care (BSC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigation of Safety, Tolerability and Pharmacokinetics of Multiple Doses of NNC0113-6856 in Healthy Participants, Including a Subset of Healthy Japanese Participants
Status: RECRUITING
Conditions: Healthy Participants
Interventions: DRUG: NNC0113-6856|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Hybrid Simulation-Based Lactation Consultancy Training on the Skills of Midwifery Students
Status: NOT_YET_RECRUITING
Conditions: Breastfeeding Consultancy Training
Interventions: OTHER: Scenario-based high-reality hybrid simulation method
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Long-term Follow-up Study for Cardiac Safety in the Patients With HER2 (+) Breast Cancer Who Have Completed the SB3-G31-BC
Status: TERMINATED
Conditions: Breast Neoplasms
Interventions: DRUG: Herceptin (trastuzumab)|DRUG: SB3 (proposed trastuzumab biosimilar)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Virulence of Staphylococcus Lugdunensis in Severe Infections
Status: COMPLETED
Conditions: Staphylococcus Lugdunensis|Bacteremia|Endocarditis|Virulence Factors
Interventions: GENETIC: Genetic blood sample
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Bioequivalence Study of Co-codamol 15mg/500mg Capsules vs Co-codamol 30mg/500mg Tablets in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: co-codamol 15mg/500mg capsule|DRUG: co-codamol 30mg/500mg tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Antidepressant Effect of Intermittent Theta Burst Stimulation (iTBS)
Status: RECRUITING
Conditions: Depression|Executive Dysfunction
Interventions: DEVICE: Transcranial magnet stimulation|DEVICE: Sham Transcranial magnet stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: β-galactosidase Producing Probiotic Strains to Improve Lactose Digestion
Status: COMPLETED
Conditions: Lactose Intolerance
Interventions: OTHER: Positive control|OTHER: Probiotic S. thermophilus|OTHER: Probiotic B. longum|OTHER: Negative control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of Differences in Video Laryngeal Mask Airway and Fastrack Laryngeal Mask
Status: RECRUITING
Conditions: The Device Placement Times|Intubation Times|Postoperative Complications
Interventions: OTHER: Video Laryngeal Mask|OTHER: Fastrack Laryngeal Mask
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Ultrasound Guided Erector Spinae Block for Postoperative Analgesia in Thoracotomy Patients
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: PROCEDURE: Erector Spinae Plane Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison Between a Telerehabilitation Program for Urinary Incontinence Versus a Conventional Face-to-face Program
Status: COMPLETED
Conditions: Stress Urinary Incontinence|Incontinence, Urinary|Covid19|Pelvic Floor Muscle Weakness
Interventions: OTHER: Pelvic Floor Telerehabilitation Program|OTHER: Pelvic Floor Face-to-Face Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study To Investigate The Pharmacokinetics, Pharmacodynamics, Safety And Tolerability Of Single Dose Vupanorsen In Healthy Chinese Adults
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Vupanorsen|DRUG: Vupanorsen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: SD-101 and BMS-986178 in Treating Patients With Advanced or Metastatic Solid Malignancies
Status: COMPLETED
Conditions: Advanced Malignant Solid Neoplasm|Extracranial Solid Neoplasm|Metastatic Malignant Solid Neoplasm
Interventions: BIOLOGICAL: Anti-OX40 Antibody BMS 986178|DRUG: TLR9 Agonist SD-101
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Volume Versus Pressure Ventilation on Lung Atelectasis
Status: ACTIVE_NOT_RECRUITING
Conditions: Cardiac Congenital Defects
Interventions: DEVICE: LMA (Laryngeal Mask Airway)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Knee vs. Ankle Training on Knee Mechanics After ACLR
Status: UNKNOWN
Conditions: ACL Tear|ACL Sprain|Anterior Cruciate Ligament Rupture|Anterior Cruciate Ligament Injuries
Interventions: OTHER: Knee then Ankle rehabilitation protocol|OTHER: Ankle then Knee rehabilitation protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: " Fume Events in Air Flights: Consequences on Cabin Air Quality and on Aircrews Health of a French Fleet of Aircraft"
Status: NOT_YET_RECRUITING
Conditions: Neurologic Symptoms|Neurologic Disorder
Interventions: DIAGNOSTIC_TEST: Neurocognitive, neuromuscular and neurosensitive tests.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: PREPARE-CALC-COMBO: Severely Calcified Coronary Lesions Prepared With Rotational Atherectomy and Modified Balloons
Status: ACTIVE_NOT_RECRUITING
Conditions: Coronary Artery Disease
Interventions: PROCEDURE: Rotational atherectomy in combination with cutting balloon
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Sorafenib Tosylate and Gemcitabine Hydrochloride in Treating Patients With Recurrent Epithelial Ovarian Cancer
Status: COMPLETED
Conditions: Recurrent Ovarian Epithelial Cancer|Recurrent Primary Peritoneal Cavity Cancer
Interventions: DRUG: gemcitabine hydrochloride|DRUG: sorafenib tosylate|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The MILESTONE Study: Improving Transition From Child to Adult Mental Health Care
Status: UNKNOWN
Conditions: Mental Health Impairment|Mental Health Disorder
Interventions: BEHAVIORAL: TRAM feedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Effect of Trendelenburg Position on the Ultrasonographic Airway Measurements
Status: UNKNOWN
Conditions: Airway Edema|Ultrasonography|Robotic Surgical Procedures|Postoperative Respiratory Complication
Interventions: PROCEDURE: General Anesthesia in Trendelenburg position for robotic prostatectomy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Establishment and Evaluation of Prenatal Prevention and Treatment Strategy for NARDS
Status: NOT_YET_RECRUITING
Conditions: Acute Respiratory Distress Syndrome|Respiratory Distress Syndrome, Acute
Interventions: DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Analgesic Efficacy of Arnica Montana in Comparison With Diclofenac Sodium Following a Periodontal Surgical Procedure
Status: COMPLETED
Conditions: Crown Lengthening Procedure With Ostectomy
Interventions: DRUG: Arnica 200 drug 3 pills,3 times daily for 3 days|DRUG: Diclofenac Sodium 50mg twice daily|DRUG: Placebo pills and distilled water 3 pills,3 times daily
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Silymarin in NAFLD
Status: WITHDRAWN
Conditions: Non-Alcoholic Fatty Liver Disease
Interventions: DRUG: Silymarin|OTHER: Placebo Oral Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Studying Biomarkers in Samples From Younger Patients With Kidney Cancer
Status: WITHDRAWN
Conditions: Childhood Kidney Neoplasm|Clear Cell Renal Cell Carcinoma|Congenital Mesoblastic Nephroma|Rhabdoid Tumor of the Kidney
Interventions: OTHER: Laboratory Biomarker Analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase III, Multi-Centre, Randomised, Placebo-Controlled Study in Combination With Ca-based P Binders in Patients With Hyperphosphatemia
Status: TERMINATED
Conditions: Chronic Kidney Disease|Dialysis|Hyperphosphatemia
Interventions: DRUG: MCI-196(colestilan(INN), Colestimide(JAN), CHOLEBINE®)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Ginger Supplement on Non-alcoholic Fatty Liver
Status: COMPLETED
Conditions: Non-alcoholic Fatty Liver Disease
Interventions: DIETARY_SUPPLEMENT: Ginger supplement|DIETARY_SUPPLEMENT: Placebo (starch)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Acute Exercise Effects in Obese Pregnancy
Status: COMPLETED
Conditions: Pregnancy Complications|Obesity|Pre-Eclampsia|Gestational Diabetes
Interventions: BEHAVIORAL: Resistance exercise|BEHAVIORAL: Aerobic Exercise|BEHAVIORAL: Rest
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Ganglionar Electrical Stimulation on Central Arterial Pressure
Status: COMPLETED
Conditions: Heart Failure|Chagas Disease
Interventions: DEVICE: TENS|DEVICE: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Investigation of Brain Network Dynamics in Depression
Status: COMPLETED
Conditions: Major Depressive Disorder, Recurrent
Interventions: DEVICE: TMS positively correlated DLPFC|PROCEDURE: TMS to negatively correlated DLPFC
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study to Investigate the Long-term Safety, Tolerability, and Efficacy of Rozanolixizumab in Study Participants With Persistent or Chronic Primary Immune Thrombocytopenia (ITP)
Status: TERMINATED
Conditions: Primary Immune Thrombocytopenia
Interventions: DRUG: Rozanolixizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Orange Aroma on Nausea, Vomiting and Anxiety During Autologous Stem Cell Transplantation
Status: COMPLETED
Conditions: Nausea|Vomiting|Anxiety State
Interventions: OTHER: Inhalation aromatherapy with orange essential oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Treatment of Fecal Incontinence After Obstetric Anal Sphincter Injuries
Status: COMPLETED
Conditions: Fecal Incontinence
Interventions: DEVICE: Medtronic Interstim II-3058|PROCEDURE: Anal bulking injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Deep Needling at Zhongliao Point to Stimulate the Sacral Nerve for the Treatment of Slow Transit Constipation
Status: RECRUITING
Conditions: Constipation
Interventions: DEVICE: Deep Acupuncture at Zhongliao Point to Stimulate Sacral Nerve|DRUG: Oral Mosapride Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: How to Develop a Training Program for Nurses in Ultrasound Guided Femoral Nerve Block
Status: COMPLETED
Conditions: Hip Fractures|Ultrasound Therapy; Complications|Pain, Acute
Interventions: OTHER: Emergency nurses
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Matched Unrelated Donor Stem Cell Transplantation (MUD-SCT) After Dose-reduced Conditioning for Patients With Multiple Myeloma and Relapse After Autologous SCT
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: PROCEDURE: allogeneic HSCT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Role of Mesocorticolimbic Pathway in Apathy of Patients With Parkinson's Disease. - Study Using Diffusion Tensor Imaging and Fibres Tracking
Status: COMPLETED
Conditions: Parkinson's Disease|Apathy
Interventions: BEHAVIORAL: Diffusion tensor imaging and fibres tracking
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Testing Pump Chemotherapy in Addition to Standard of Care Chemotherapy Versus Standard of Care Chemotherapy Alone for Patients With Unresectable Colorectal Liver Metastases: The PUMP Trial
Status: RECRUITING
Conditions: Metastatic Colorectal Carcinoma|Metastatic Malignant Neoplasm in the Liver|Stage IV Colorectal Cancer AJCC v8|Unresectable Colorectal Carcinoma
Interventions: BIOLOGICAL: Bevacizumab|BIOLOGICAL: Cetuximab|PROCEDURE: Computed Tomography|DRUG: Floxuridine|DRUG: Fluorouracil|PROCEDURE: Implantation|PROCEDURE: Intrahepatic Infusion Procedure|DRUG: Irinotecan|DRUG: Leucovorin|DRUG: Oxaliplatin|BIOLOGICAL: Panitumumab|PROCEDURE: Single Photon Emission Computed Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence of a Fixed Dose Combination Tablet of Empagliflozin/Metformin Extended Release Compared With Mono Compound Tablets in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: metformin|DRUG: empagliflozin/metformin|DRUG: empagliflozin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Parasternal Blocks in Cardiovascular Surgery Patients Undergoing Median Sternotomy
Status: RECRUITING
Conditions: Postoperative Pain
Interventions: PROCEDURE: 1. no block|PROCEDURE: 2. superficial parasternal block|PROCEDURE: 3. deep parasternal block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Fenobam on Heat/Capsaicin Induced Hyperalgesia in Healthy Volunteers
Status: COMPLETED
Conditions: Hyperalgesia|Allodynia
Interventions: DRUG: Fenobam|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: BLOCK-SAH - PPF-Block for Post-SAH Headache
Status: RECRUITING
Conditions: Subarachnoid Hemorrhage, Aneurysmal|Headache
Interventions: DRUG: Pterygopalatine Fossa Nerve Block with Ropivacaine and Dexamethasone|PROCEDURE: Placebo Pteryogpalatine Fossa Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of a Case Management Model for Patients With Hypertension and Type II Diabetes in Chile
Status: UNKNOWN
Conditions: Hypertension|Diabetes Mellitus, Type 2
Interventions: OTHER: Case Management|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tandem Stem Cell Transplantation for Non-Hodgkin's Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Lymphoma, Non-Hodgkin
Interventions: PROCEDURE: Stem cell infusion|PROCEDURE: TLI|DRUG: Anti-thymocyte globulin|DRUG: Solumedrol|DRUG: Tacrolimus|DRUG: Mycophenolate mofetil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Short Course of Miltefosine and Liposomal Amphotericin B for Kala-azar
Status: COMPLETED
Conditions: Visceral Leishmaniasis
Interventions: DRUG: Liposomal amphotericin B and Miltefosine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Intra-Drug Eluting Stent (DES) Restenosis Study
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DEVICE: drug-eluting stent and balloon angioplasty|DEVICE: drug-eluting stent and balloon angioplasty|DEVICE: drug-eluting stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Coronary Atherosclerosis Evaluation by Arterial Wall Magnetic Resonance Imaging (MRI)
Status: COMPLETED
Conditions: Coronary Arteriosclerosis|Arteriosclerosis, Coronary|Atherosclerosis, Coronary|Coronary Artery Disease|Coronary Atherosclerosis
Interventions: PROCEDURE: MR Imaging of the Coronary Arteries
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Trials of Clinical Curative Effect, Follow-up Study and Hemodynamics of Treatment of IA Using Stents
Status: UNKNOWN
Conditions: Treatment Outcome by Stent-assisted Embolization
Interventions: DEVICE: LVIS stent|DEVICE: Solitire stent|DEVICE: Enterprise stent|DEVICE: Neuroform stent|DEVICE: Pipeline stent
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study Comparing 3 Dosage Levels Of SAM-531 In Outpatients With Mild To Moderate Alzheimer Disease
Status: TERMINATED
Conditions: Alzheimer Disease
Interventions: DRUG: Placebo|DRUG: SAM-531 1.5 mg|DRUG: SAM-531 3.0 mg|DRUG: SAM-531 5.0 mg|DRUG: Donepezil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalency Study of Buprenorphine Hydrochloride 8 mg Tablet Under Fasted Conditions
Status: COMPLETED
Conditions: Opioid-Related Disorders
Interventions: DRUG: buprenorphine hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Topical Azelaic Acid 15% Gel Plus Anti-inflammatory Dose Doxycycline or Metronidazole Gel 1% Plus Anti-inflammatory Dose Doxycycline in Moderate Papulopustular Rosacea
Status: COMPLETED
Conditions: Papulopustular Rosacea
Interventions: DRUG: Azelaic acid (Finacea, BAY39-6251)|DRUG: Metronidazole (Metrogel)|DRUG: Doxycycline (Oracea)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: SERRATHOR TRIAL : Interest of the Novel Serratus Plane Block in Post Operative Analgesia After Video-Assisted Thoracoscopic Lobectomy
Status: UNKNOWN
Conditions: Video Assisted Thoracoscopic Surgery|Lobectomy|Pain Post Operative|Regional Anesthesia
Interventions: DRUG: Ropivacaine|DRUG: sterile saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study Comparing Cardiovascular Effects of Ticagrelor Versus Placebo in Patients With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Ticagrelor 60 mg|DRUG: Ticagrelor placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Clinical Evaluation of the Eclipse™ System, a Vaginal Bowel Control (VBC) Therapy for Fecal Incontinence in Women
Status: COMPLETED
Conditions: Fecal Incontinence
Interventions: DEVICE: Eclipse™ System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Detection of Herpesvirus DNA (CMV, EBV, HHV-6 and HSV) in Colonic Tissue: Impact on Ulcerative Colitis Flare-up
Status: ACTIVE_NOT_RECRUITING
Conditions: Colitis, Ulcerative
Interventions: PROCEDURE: rectosigmoidoscopy|BIOLOGICAL: biopsies|BIOLOGICAL: blood sample
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Testing How Well Magnesium Citrate Capsules Work as Preparation for a Colonoscopy
Status: COMPLETED
Conditions: Colonoscopy
Interventions: DIETARY_SUPPLEMENT: Magnesium Citrate Capsules|OTHER: Polyethylene Glycol 3350|OTHER: Dulcolax Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SCREENING
Clinical trial: Clinical Investigation of the Medtronic EnTrust™ Implantable Cardioverter Defibrillator (ICD), Model D153ATG
Status: COMPLETED
Conditions: Ventricular Arrhythmias
Interventions: DEVICE: Implantable Cardioverter Defibrillator
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of Safety and Efficacy of Sodium Phenylbutyrate in Spinocerebellar Ataxia Type 3
Status: WITHDRAWN
Conditions: Spinocerebellar Ataxia Type 3
Interventions: DRUG: Placebo|DRUG: Sodium Phenylbutyrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT