pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Study of Effects of Sacubitril/Valsartan vs. Enalapril on Aortic Stiffness in Patients With Mild to Moderate HF With Reduced Ejection Fraction
Status: COMPLETED
Conditions: Heart Failure and Reduced Ejection Fraction
Interventions: DRUG: LCZ696 (sacubitril/valsartan)|DRUG: Enalapril|DRUG: Placebo of Enalapril|DRUG: Placebo of LCZ696
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Low-dose Intra-articular Tranexamic Acid in Total Knee Replacement
Status: COMPLETED
Conditions: Primary Osteoarthritis of Knee Nos
Interventions: DRUG: Tranexamic Acid|DRUG: Physiologic saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Evaluate Safety and Effectiveness of Noble Lift® Lifting Threads
Status: NOT_YET_RECRUITING
Conditions: Aesthetic
Interventions: DEVICE: Eyebrow lift|DEVICE: Jaw lift
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: NBTXR3 Nanoparticles and EBRT or EBRT With Brachytherapy in the Treatment of Prostate Adenocarcinoma
Status: TERMINATED
Conditions: Prostate Cancer
Interventions: DRUG: NBTXR3 activated by IMRT only|DRUG: NBTXR3 activated by Brachytherapy & IMRT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neural Mechanisms of Enhancing Emotion Regulation in Bereaved Spouses
Status: RECRUITING
Conditions: Affect|Bereavement|Emotions|Depressive Symptoms|Grief
Interventions: BEHAVIORAL: Cognitive Emotion Regulation Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Cannabis Use Disorder Treatment Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Cannabis Use Disorder, Mild|Cannabis Use Disorder, Moderate|Cannabis Use Disorder, Severe
Interventions: BEHAVIORAL: Peer Network Counseling-txt
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Indirect Calorimeter Based Study in Patients With Liver Cirrhosis
Status: COMPLETED
Conditions: Liver Cirrhoses
Interventions: OTHER: Indirect calorimetry based nutritional intervention till patient in ICU(Intensive care unit)|OTHER: Standard and fixed nutritional intervention till patient in ICU
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Effects of Itraconazole and Rifampin on Lazertinib in Healthy Adult Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Lazertinib|DRUG: Itraconazole|DRUG: Rifampin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Swallowing Training in Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson's Disease|Deglutition Disorders|Voice Disorders
Interventions: OTHER: Motor exercises for swallowing, breathing and phonation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: NHLBI Type II Coronary Intervention Study
Status: COMPLETED
Conditions: Cardiovascular Diseases|Coronary Disease|Heart Diseases|Hypercholesterolemia, Familial|Myocardial Infarction|Myocardial Ischemia
Interventions: DRUG: cholestyramine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Effect of Non-pharmacological Anti-anxiety Exercises on Perceived Stress and Cortisol Level Before Elective Per Cutaneous Transluminal Coronary Angioplasty
Status: COMPLETED
Conditions: Percutaneous Transluminal Coronary Angioplasty
Interventions: OTHER: reflexology|OTHER: breathing exercise|OTHER: standard care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial on the Safety and Efficacy of TQB3909 Tablets in Patients With Recurrent or Refractory Chronic Lymphocytic Leukemia (CLL) /Small Lymphocytic Lymphoma (SLL) .
Status: RECRUITING
Conditions: Chronic Lymphocytic Leukemia|Small Lymphocytic Lymphoma
Interventions: DRUG: TQB3909 tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Enthesitis With Ultra Sonography Doppler in Spondyloarthropathies Treated With Infliximab (Study P04440)
Status: TERMINATED
Conditions: Spondylitis, Ankylosing|SpA
Interventions: PROCEDURE: PDUS|DRUG: Infliximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Prevention of Recurrent UTI Using Vaginal Testosterone Versus Placebo Placebo
Status: RECRUITING
Conditions: Recurrent Urinary Tract Infection|Vaginal Atrophy|Postmenopausal Disorder
Interventions: DRUG: Vaginal Cream with Applicator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ultrasound Measurements of Circular Cartilage Transverse Diameter
Status: UNKNOWN
Conditions: Ultrasound Therapy; Complications|Transverse Diameter of Cricoid Cartilage|Endotracheal Intubation|Children
Interventions: DEVICE: Portable color Doppler ultrasound system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rheumatoid Arthritis Shared Decision Making
Status: RECRUITING
Conditions: Rheumatoid Arthritis
Interventions: BEHAVIORAL: Clinician communication training|BEHAVIORAL: Patient activation|BEHAVIORAL: RA Medication summary guide and RA Choice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Flavanol Absorption, Metabolism and Excretion From Fruit-based Drinks and Other Food Matrixes
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: Flavanols-capsules|OTHER: Flavanol-banana blend|OTHER: Flavanol-high protein drink|OTHER: Flavanol-berry blend|OTHER: Flavanol-sports drink|OTHER: Flavanol-peanut butter toast|OTHER: Flavanol-oats|OTHER: Flavanol-yogurt|OTHER: II- Flavanol drink|OTHER: II- Flavanol drink + banana blend
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Testosterone Replacement in Non-alcoholic Steatohepatitis (TEREPINS)
Status: COMPLETED
Conditions: Nonalcoholic Steatohepatitis|Hypogonadism
Interventions: DRUG: testosterone undecanoate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mandibular Advancement Device for Treatment of Obstructive Sleep Apnea and Its Impact on Cardiac Remodeling
Status: UNKNOWN
Conditions: Obstructive Sleep Apnea|Heart Failure
Interventions: DEVICE: Mandibular advancement device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of an Irreversible Electroporation (IRE) System for Tonsil Reduction for The Treatment of Chronic Symptomatic Tonsillar Hypertrophy
Status: RECRUITING
Conditions: Tonsillar Hypertrophy
Interventions: DEVICE: IRE System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Heparin Intraoperative Instillation for Lower Urinary Tract Symptoms After Benign Hysterectomy
Status: UNKNOWN
Conditions: Lower Urinary Tract Symptoms|Postoperative Urinary Tract Infection
Interventions: DRUG: Heparin|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Stenting Versus Best Medical Treatment of Asymptomatic High Grade Carotid Artery Stenosis
Status: COMPLETED
Conditions: Asymptomatic|Artery
Interventions: DEVICE: carotid artery stenting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Autologous Mesenchymal Stem Cells Transplantation for Spinal Cord Injury- A Phase I Clinical Study
Status: COMPLETED
Conditions: Spinal Cord Injury
Interventions: BIOLOGICAL: mesenchymal stem cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The OsteoStrand Plus Deformity Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Spinal Fusion
Interventions: PROCEDURE: Posterolateral Lumbar Fusion with Demineralized Bone Fibers|PROCEDURE: Posterolateral Lumbar Fusion with Bone Morphogenic Protein
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adherence of a 1.600 mg Single Tablet 5-ASA Treatment of Ulcerative Colitis
Status: RECRUITING
Conditions: Ulcerative Colitis
Interventions: DRUG: Mesalazine|DRUG: Mesalazine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety of N-acetylcysteine in Maternal Chorioamnionitis (NAC in Chorio)
Status: COMPLETED
Conditions: Chorioamnionitis|Brain Injury
Interventions: DRUG: N-acetylcysteine|DRUG: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study for Patients With Head and Neck Cancer
Status: COMPLETED
Conditions: Head and Neck Neoplasms
Interventions: DRUG: pemetrexed|DRUG: cisplatin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Investigate the Absorption, Metabolism, and Excretion of [14C]-Pamiparib in Participants With Advanced Cancer
Status: COMPLETED
Conditions: Advanced Solid Tumors
Interventions: DRUG: [14C]-pamiparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Disruption of Memory Reconsolidating as a Treatment for Panic Disorder
Status: UNKNOWN
Conditions: Panic Disorder
Interventions: DRUG: Propranolol|DRUG: Placebo|OTHER: Carbon dioxide|OTHER: Compressed air
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Effects of Dissolution Profile on the Pharmacokinetics of Single Oral Doses of Tafenoquine Tablets and Tafenoquine Stable Isotope Labelled Solution
Status: COMPLETED
Conditions: Malaria, Vivax
Interventions: DRUG: Tafenoquine Control|DRUG: Tafenoquine dissolution profile X|DRUG: Tafenoquine SIL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TES RCT Fleet Enema vs Oral Mechanical Bowel Prep
Status: RECRUITING
Conditions: Colorectal Neoplasms|Surgery
Interventions: DRUG: Fleet Enema|DRUG: Pico-Salax
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Identification of Oral Lesions Through an Autofluorescence System
Status: RECRUITING
Conditions: Oral Leukoplakia|Autofluorescence|Secondary Prevention|Keratosis|Oral Lichen Planus|Oral Cancer|Oral Disease
Interventions: DEVICE: Screening examination
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Effects of Diet Versus Diet Plus Aerobic and Resistant Exercise Program in Overweight Women
Status: RECRUITING
Conditions: Overweight|Exercise
Interventions: OTHER: Aerobic and resistance exercises|DIETARY_SUPPLEMENT: Diet program|OTHER: Regular walking program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study to Evaluate a Telepharmacy Intervention to Improve Inhaler Adherence in Veterans With COPD
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: BEHAVIORAL: COPD Inhaler Counseling|BEHAVIORAL: Usual Pharmacy Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Add-on Aliskiren Treatment in Patients With Chronic Congestive Heart Failure
Status: UNKNOWN
Conditions: Congestive Heart Failure
Interventions: DRUG: Aliskiren|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Infigratinib in Subjects With GC or GEJ With FGFR2 Amplification or Other Solid Tumors With Other FGFR Alterations
Status: UNKNOWN
Conditions: Gastric Cancer|Gastroesophageal Junction Adenocarcinoma|Solid Tumor
Interventions: DRUG: Infigratinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Duac® Gel And Differin® Gel in Mild to Moderate Acne Vulgaris
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: Duac® Gel / Differin® Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: High Dose Chemotherapy and Allogeneic Hematopoietic Cell Transplant for Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Lymphoma, Non-Hodgkin|Blood and Marrow Transplant (BMT)|Lymphomas: Non-Hodgkin
Interventions: PROCEDURE: ablative allogeneic hematopoietic cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Stinging Potential of Products in Human Eyes
Status: COMPLETED
Conditions: Sunscreen Agents
Interventions: DRUG: BAY987516, Y55-170|DRUG: BAY987516, X72-151|DRUG: BAY987516, Y49-034|DRUG: Standard shampoo mixture (control)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: The External Diaphragm Pacemaker Assisted Extubation in Premature Infants With Invasive Mechanical Ventilation
Status: RECRUITING
Conditions: Invasive Mechanical Ventilation|Extubation
Interventions: DEVICE: External Diaphragm Pacemaker treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of IMM 124-E (Bovine Colostrum) for Patients With Nonalcoholic Steatohepatitis
Status: WITHDRAWN
Conditions: Nonalcoholic Steatohepatitis
Interventions: BIOLOGICAL: IMM 124-E|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Hyperpolarized Magnetic Resonance Imaging in Asthma Pre- and Post-Bronchial Thermoplasty
Status: COMPLETED
Conditions: Asthma
Interventions: PROCEDURE: Conventional Bronchial Thermoplasty|PROCEDURE: Image Guided Bronchial Thermoplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Naloxone to TReatment Entry in the Emergency Setting
Status: WITHDRAWN
Conditions: Opioid Dependence|Opioid Intoxication|Substance Use Disorders
Interventions: BEHAVIORAL: Active treatment referral of opioid overdose survivors to long-term treatment|BEHAVIORAL: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Black Cohosh Extract for the Management of Moderate to Severe Menopausal Symptoms in Thai Women
Status: UNKNOWN
Conditions: Hot Flashes
Interventions: DRUG: cimicifuga racemosa|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PK Study to Assess Drug-drug Interaction and QTc Between Sitravatinib and a Cocktail of Substrates
Status: COMPLETED
Conditions: Advanced Solid Tumor
Interventions: DRUG: Sitravatinib|DRUG: Warfarin|DRUG: Dextromethorphan|DRUG: Midazolam|DRUG: Digoxin|DRUG: Rosuvastatin|DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of MK-1075 in Participants With Hepatitis C Virus (HCV) Infection (MK-1075-002)
Status: COMPLETED
Conditions: Hepatitis C
Interventions: DRUG: MK-1075
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study in Participants With Epilepsy, to Evaluate the Pharmacokinetics, Safety and Tolerability of Oxcarbazepine on Padsevonil
Status: COMPLETED
Conditions: Epilepsy
Interventions: DRUG: Padsevonil|DRUG: Oxcarbazepine|DRUG: Levetiracetam|DRUG: Lamotrigine|DRUG: Brivaracetam
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect of Low-Level Laser Therapy as an Adjunct to Non-surgical Therapy in Different Age Groups
Status: COMPLETED
Conditions: Periodontal Inflammation
Interventions: OTHER: diode laser|OTHER: non surgical scaling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Platelet Rich Plasma (PRP) Bio Stimulant Gel Dressing in Treating Chronic Non Healing Leg and Foot Ulcers: Cost and Effectiveness
Status: COMPLETED
Conditions: Ulcer Foot|Chronic Skin Ulcer|Non-Healing Ulcer of Skin
Interventions: PROCEDURE: PRP dressing|PROCEDURE: conventional ordinary dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study in Healthy Men to Test How Itraconazole Influences the Amount of BI 474121 in the Blood
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BI 474121|DRUG: Itraconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multiple Dose Study of Repeat Intravitreal Injections of GEM103 in Neovascular Age-related Macular Degeneration
Status: TERMINATED
Conditions: Neovascular Age-related Macular Degeneration|Retinal Disease|Retinal Degeneration|Macular Degeneration
Interventions: BIOLOGICAL: GEM103|DRUG: Aflibercept|DRUG: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study of the Effects of HIRREM-SOP for Insomnia
Status: COMPLETED
Conditions: Insomnia|Sleep Deprivation
Interventions: DEVICE: HIRREM-SOP|DEVICE: NCC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Minocycline and Perfusion Pressure Augmentation in Acute Spinal Cord Injury
Status: COMPLETED
Conditions: Spinal Cord Injuries
Interventions: DRUG: Minocycline|DRUG: placebo|PROCEDURE: SCPP augmentation|PROCEDURE: SCPP control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: RElated Haplo-DonoR Haematopoietic stEm Cell Transplantation for Adults With Severe Sickle Cell Disease
Status: RECRUITING
Conditions: Sickle Cell Disease
Interventions: PROCEDURE: Haploidentical stem cell transplantation|OTHER: Standard medical care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 18F-FSPG PET/CT for Cancer Patients on Therapy
Status: COMPLETED
Conditions: B-Cell Neoplasm|Estrogen Receptor Negative|HER2/Neu Negative|Metastatic Renal Cell Cancer|Progesterone Receptor Negative|Stage III Mesothelioma|Stage III Renal Cell Cancer|Stage IIIA Breast Cancer|Stage IIIA Non-Small Cell Lung Cancer|Stage IIIB Non-Small Cell Lung Cancer|Stage IIIC Breast Cancer|Stage IV Breast Cancer|Stage IV Mesothelioma|Stage IV Non-Small Cell Lung Cancer|Stage IV Renal Cell Cancer|Triple-Negative Breast Carcinoma
Interventions: DRUG: 18F-FSPG|DRUG: 18F-FDG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Singulair® add-on Study Effectiveness of Adding Montelukast to Inhaled Corticosteroids in Adult Subjects With Uncontrolled Asthma (0476-384)
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: montelukast sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Carboplatin, Gemcitabine Hydrochloride, and Stereotactic Body Radiation Therapy in Gynecological Cancer
Status: COMPLETED
Conditions: Leydig Cell Tumor|Ovarian Sarcoma|Ovarian Stromal Cancer|Pseudomyxoma Peritonei|Recurrent Cervical Cancer|Recurrent Endometrial Carcinoma|Recurrent Fallopian Tube Cancer|Recurrent Ovarian Epithelial Cancer|Recurrent Ovarian Germ Cell Tumor|Recurrent Primary Peritoneal Cavity Cancer|Recurrent Uterine Sarcoma|Recurrent Vaginal Cancer|Recurrent Vulvar Cancer
Interventions: RADIATION: stereotactic body radiation therapy|DRUG: carboplatin|DRUG: gemcitabine hydrochloride|OTHER: laboratory biomarker analysis|OTHER: pharmacogenomic studies
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Inhaled Corticosteroids for Treatment of Bronchopulmonary Dysplasia
Status: COMPLETED
Conditions: Bronchopulmonary Dysplasia
Interventions: DRUG: Inhaled Beclomethasone Dipropionate Monohydrate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Simulation-based and Problem-based Learning for Difficult Airway Management
Status: UNKNOWN
Conditions: Education
Interventions: PROCEDURE: Simulation training|PROCEDURE: Problem-based learning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effects of Carnipure® Tartrate on Postprandial Endothelial Function and Recovery
Status: COMPLETED
Conditions: Healthy Volunteers|Recovery|Endothelial Function
Interventions: DIETARY_SUPPLEMENT: L-Carnitine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Vaginoscopy Compared to Traditional Hysteroscopy for Hysteroscopy Morcellation in Outpatient Clinic. A Randomized Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Leiomyoma of Uterus
Interventions: PROCEDURE: vaginoscopy|PROCEDURE: standard hysteroscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multimodalitic Imaging in the N-stage of Lung Cancer
Status: NOT_YET_RECRUITING
Conditions: Neoplasm of Lung
Interventions: DRUG: 18F-FDG|DEVICE: MR STIR|PROCEDURE: EBUS-TBNA
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Nab-paclitaxel and Gemcitabine in Metastatic Pancreatic Cancer
Status: UNKNOWN
Conditions: Metastatic Pancreatic Cancer
Interventions: DRUG: Paclitaxel for Injection（Albumin Bound）|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Intensive Insulin Therapy in the Surgical Critical Care Unit
Status: COMPLETED
Conditions: Sepsis|Respiratory Failure|Renal Failure|Surgical Site Infection
Interventions: DRUG: Novolin R (human recombinant Insulin)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Advanced Hybrid Closed Loop (AHCL) System in Type 1 Adults and Pediatrics Utilizing Lyumjev®
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: DEVICE: MiniMed 780G System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Efficacy and Safety of Once-Weekly Oral NBI-1065846 in the Treatment of Anhedonia in MDD
Status: COMPLETED
Conditions: Anhedonia|Major Depressive Disorder
Interventions: DRUG: Placebo|DRUG: NBI-1065846
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multisensory Stimulation on Postoperative Pain, Physiological Parameters and Fear in Children
Status: NOT_YET_RECRUITING
Conditions: Multisensory Stimulation|Child, Only|Postoperative Pain|Fear
Interventions: OTHER: Multisensory Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Non-Invasive Diagnosis of Pediatric Pulmonary Invasive Mold Infections
Status: RECRUITING
Conditions: Pulmonary Invasive Fungal Infections|Pulmonary Invasive Aspergillosis
Interventions: DIAGNOSTIC_TEST: Non-Invasive Testing for PIFI
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Inducible Laryngeal Obstruction in Severe Asthma in Severe Asthma
Status: ACTIVE_NOT_RECRUITING
Conditions: Asthma Chronic|Vocal Cord Dysfunction
Interventions: DIAGNOSTIC_TEST: Continous laryngoscopy exercise test|DIAGNOSTIC_TEST: Overnight respiratory polygraphy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Testing New Vertical Dimension Of Occlusion Prior To Restorative Treatment Of Tooth Wear
Status: COMPLETED
Conditions: Tooth Wear|Randomized Controlled Trial|Vertical Dimension of Occlusion|Composite Resins
Interventions: DEVICE: acrylic removable appliance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Ergonomic Training With Exercise Program for Work-related Musculoskeletal Disorders Among Hemodialysis Nurse
Status: COMPLETED
Conditions: Musculoskeletal Disorders
Interventions: OTHER: ergonomic training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Efficacy of KRT-232 in Combination With Acalabrutinib in Subjects With R/R DLBCL or R/R CLL
Status: UNKNOWN
Conditions: Diffuse Large B Cell Lymphoma|Chronic Lymphocytic Leukemia|Non Hodgkin Lymphoma
Interventions: DRUG: KRT-232|DRUG: acalabrutinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tegafur-Uracil and Leucovorin or S-1 in Treating Patients With Stage III Colon Cancer That Has Been Completely Removed by Surgery
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: folinate calcium|DRUG: tegafur-uracil|DRUG: tegafur-gimeracil-oteracil potassium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Post-Market Randomized Trial: Endoscopically- Guided Ablation vs. Radiofrequency Ablation
Status: TERMINATED
Conditions: Paroxysmal Atrial Fibrillation
Interventions: DEVICE: Endoscopically guided PVI Ablation|DEVICE: RF PVI Ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Measurement of Diaphragmatic Dysfunction After Thoracic Surgery
Status: COMPLETED
Conditions: Diaphragm Injury|Phrenic Nerve Paralysis|Thoracic Cancer|Postoperative Complications
Interventions: PROCEDURE: Lung lobectomy OR esophagus cancer resection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Mindfulness-based Intervention for Treatment of Anxiety in ICD (Implantable Cardioverter Defibrillator) Patients
Status: COMPLETED
Conditions: Anxiety Disorder in Conditions Classified Elsewhere
Interventions: BEHAVIORAL: mindfulness based intervention (MBI)|BEHAVIORAL: usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Three-dimensional Craniofacial Phenotyping of Patients With Difficult Airway
Status: TERMINATED
Conditions: Failed or Difficult Intubation
Interventions: PROCEDURE: 3D Laser Scanning of the Head|PROCEDURE: Measurements and Digital Photo's of the head, neck and Mouth|PROCEDURE: Ultrasound Exam of the Tongue|PROCEDURE: 3D Laser Scanning of the Head|PROCEDURE: Measurements and Digital Photo's of the head, neck and Mouth|PROCEDURE: Ultrasound Exam of the Tongue
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Food on a Fixed Dose Combination Tablet of Canagliflozin and Metformin Immediate Release in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: A (CANA/MET IR FDC tablet - fasting state) / B (CANA/MET IR FDC tablet - fed state)|DRUG: B (CANA/MET IR FDC tablet - fed state) / A (CANA/MET IR FDC tablet - fasting state)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Psilocybin-facilitated Smoking Cessation Treatment: A Pilot Study
Status: COMPLETED
Conditions: Nicotine Dependence
Interventions: DRUG: Psilocybin-assisted treatment|DRUG: Nicotine Replacement Therapy (NRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study of Alemtuzumab (Campath[R]) in Patients With Myelodysplastic Syndrome
Status: COMPLETED
Conditions: Myelodysplastic Syndromes
Interventions: DRUG: Alemtuzumab (Campath)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Contribution of L-Tyrosine to Recovery From Operational Strain on Return From External Operation
Status: COMPLETED
Conditions: Stress, Psychological
Interventions: BIOLOGICAL: Blood collection|DRUG: L-Tyrosine 500 Mg|BEHAVIORAL: Psychological questionnaires|DEVICE: Photoplethysmography|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Effect of Activated Charcoal With Sorbitol on the Single-dose of Mavacamten in Healthy Participants
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DRUG: Mavacamten|DRUG: Activated Charcoal with Sorbitol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of Dupilumab in Adult and Adolescent Patients With Moderate-to-Severe Atopic Hand and Foot Dermatitis (Liberty-AD-HAFT)
Status: COMPLETED
Conditions: Moderate to Severe Atopic Hand and Foot Dermatitis
Interventions: DRUG: dupilumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Activation of Cervical and Upper Thoracic Brown Adipose Tissue in Humans Via Beta-adrenergic Stimulation
Status: COMPLETED
Conditions: Obesity
Interventions: DRUG: ephedrine hydrochloride|DRUG: ephedrine hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of Nivolumab by Itself or Nivolumab Combined With Ipilimumab in Patients With Advanced or Metastatic Solid Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced or Metastatic Solid Tumors
Interventions: BIOLOGICAL: Nivolumab|BIOLOGICAL: Ipilimumab|DRUG: Cobimetinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Randomized Trial of Polypectomy Techniques for 4-6 mm Colonic Polyps
Status: COMPLETED
Conditions: Colon Polyps
Interventions: PROCEDURE: Cold forceps|PROCEDURE: Cold snare|PROCEDURE: Hot snare
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Differentiation of Asthma/COPD Exacerbation and Stable State Using Automated Lung Sound Analysis With LungPass Device
Status: UNKNOWN
Conditions: Asthma|COPD
Interventions: DEVICE: Lung auscultation with LungPass device (electronic auscultation)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Hormonal Status on Blood Flow and Tissue in Pelvic Organ Prolapse
Status: TERMINATED
Conditions: Pelvic Floor Disorders
Interventions: DRUG: Postmenopausal, topical vaginal estrogen cream|DRUG: Placebo Comparator: Postmenopausal, topical placebo cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Immediate Release Versus Extended Release Torsemide After Salty Meal
Status: RECRUITING
Conditions: Heart Failure
Interventions: DRUG: Immediate release torsemide 20mg tablet|DRUG: Extended release torsemide 24mg tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intravitreal Aflibercept as Indicated by Real-Time Objective Imaging to Achieve Diabetic Retinopathy Improvement
Status: COMPLETED
Conditions: Diabetic Retinopathy
Interventions: DRUG: Aflibercept Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immediate Loading and Fully Guided Surgery: Single Implants
Status: COMPLETED
Conditions: Osseointegration Failure of Dental Implant
Interventions: PROCEDURE: Immediate loading, fully guided surgery and 3D printed restoration|PROCEDURE: Immediate loading
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Efficacy and Safety of Switching to VM-1500A-LAI + 2NRTIs From the 1st Line Standard of Care Therapy
Status: UNKNOWN
Conditions: HIV-1-infection
Interventions: DRUG: VM-1500A-LAI|OTHER: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of a Plant-Based Diet and Dietary Supplements in People With Smoldering Multiple Myeloma (SMM)
Status: RECRUITING
Conditions: Multiple Myeloma, Smoldering
Interventions: DIETARY_SUPPLEMENT: Omega-3|DIETARY_SUPPLEMENT: Curcumin|DIETARY_SUPPLEMENT: Probiotic|OTHER: Whole food, plant-based diet (WFPBD)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Low-dose Esketamine on Maternal Depression at 2 Years After Childbirth
Status: ACTIVE_NOT_RECRUITING
Conditions: Prenatal Depression|Ketamine|Postpartum Depression
Interventions: DRUG: Esketamine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Atorvastatin in Bronchiectasis in Patients With Pseudomonas Aeruginosa
Status: COMPLETED
Conditions: BRONCHIECTASIS
Interventions: DRUG: ATORVASTATIN
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Ticilimumab in Patients With Metastatic Colorectal Cancer Whose Disease Had Progressed After Treatment
Status: COMPLETED
Conditions: Colorectal Neoplasms
Interventions: DRUG: CP-675,206
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Protein Turnover in the Osteoarthritic Knee
Status: COMPLETED
Conditions: Osteo Arthritis Knee|Protein Metabolism
Interventions: DIETARY_SUPPLEMENT: Preoperative protein supplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Absorption, Metabolism, and Excretion of (-)-[2-14C]Epicatechin in Humans
Status: COMPLETED
Conditions: ADME
Interventions: OTHER: Controlled dietary background|OTHER: (-)-[2-14C]epicatechin intake
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Comparison of Different De-epithelialization Techniques of Soft Tissue Grafts.
Status: COMPLETED
Conditions: Connective Tissue Graft Harvesting
Interventions: PROCEDURE: Intraorally de-epithelialization|PROCEDURE: Extraorally de-epithelialization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Whey Protein Supplementation on Vascular and Cognitive Function in Older Adults
Status: COMPLETED
Conditions: Blood Pressure
Interventions: DIETARY_SUPPLEMENT: Whey protein supplement|DIETARY_SUPPLEMENT: Carbohydrate supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Opioid Treatment Program (OTP)-Pharmacy Collaboration for Methadone Maintenance Treatment
Status: COMPLETED
Conditions: Opioid-use Disorder
Interventions: DRUG: Pharmacy-based methadone administration and dispensing
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: PPV: Pneumococcal Polysaccharide Vaccine in Older Adults
Status: COMPLETED
Conditions: Aging
Interventions: BIOLOGICAL: Pneumococcal Vaccine|BIOLOGICAL: Meningococcal Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility Study of New MRI Protocol in Assessing Early Blood Brain Barrier Disruption (BBBD)in Related to Delay Brain Edema
Status: UNKNOWN
Conditions: Intra Cerebral Hemorrhage
Interventions: DEVICE: MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Phase 1b Study of PPI-461 in Patients With HCV Genotype 1
Status: COMPLETED
Conditions: Chronic Genotype 1 Hepatitis C Virus Infection
Interventions: DRUG: PPI-461|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Pancreatic Tissue Penetration of Meronem® in the Prophylaxis of Septic Complications in Severe Pancreatitis
Status: COMPLETED
Conditions: Pancreatitis
Interventions: DRUG: Meropenem
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pemetrexed Disodium With or Without Sorafenib as Second-Line Therapy in Treating Patients With Stage IIIB or Stage IV Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DRUG: pemetrexed disodium|DRUG: sorafenib tosylate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Polyunsaturated Fatty Acids (PUFA) on Allergic/Atopic Dermatitis
Status: WITHDRAWN
Conditions: Atopic Dermatitis
Interventions: DIETARY_SUPPLEMENT: DHA+EPA|DIETARY_SUPPLEMENT: High Olive Oil|DIETARY_SUPPLEMENT: DHA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Cohort Study on Biomarkers and Clinical Treatment of Tinnitus
Status: RECRUITING
Conditions: Tinnitus, Subjective|Acoustic Stimulation|Transcranial Magnetic Stimulation, Repetitive|Magnetoencephalography
Interventions: DEVICE: Acoustic stimulation|DEVICE: Repetitive transcranial magnetic stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Fish-oil on Mood and Cognitive Functions of Healthy Individuals
Status: COMPLETED
Conditions: Depression
Interventions: DIETARY_SUPPLEMENT: omega-3 fatty acids supplements (fish oil)|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: NEOX® CORD 1K vs Standard of Care in Non-healing Diabetic Foot Ulcers
Status: TERMINATED
Conditions: Foot Ulcer, Diabetic
Interventions: OTHER: NEOX® CORD 1K|PROCEDURE: Standard of Care (Pressure Bandage)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intermittent-pneumatic Compression in Inhalation-injury Children: Effects on Diaphragm Mobility and Pulmonary Function
Status: RECRUITING
Conditions: Inhalation Injury
Interventions: OTHER: intermittent pneumatic compression, physiotherapy, and walking|OTHER: physiotherapy and walking
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Antibiotic Prophylaxis in Prelabor Rupture of Membranes at Term
Status: COMPLETED
Conditions: Chorioamnionitis|Puerperal Endometritis|Neonatal Early Onset Sepsis|Neonatal Meningitis|Neonatal Pneumonia
Interventions: DRUG: Ampicillin + gentamicin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Safety Clinical Trial of Different Doses of MEDI-507 in the Prevention of Acute Renal Allograft Rejection
Status: COMPLETED
Conditions: Kidney Diseases
Interventions: DRUG: MEDI-507|DRUG: MEDI-507|DRUG: MEDI-507|DRUG: MEDI-507|DRUG: MEDI-507
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SUBclavian Central Venous Catheters Guidance and Examination by UltraSound
Status: COMPLETED
Conditions: Requiring Subclavian Vein Cannulation|Adult Patients|Patient Covered by French Health Care System
Interventions: OTHER: Ultrasound-guided cannulation and examination
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Role of Inflammation and Vasodilatation in PACAP38-induced Headache Using MRI on Healthy Subjects
Status: COMPLETED
Conditions: Headache
Interventions: OTHER: Sumatriptan|OTHER: Ketorolac
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Study to Explore the Effect of Secukinumab, Compared to Placebo, on Fat Tissue and Skin in Plaque Psoriasis Patients
Status: COMPLETED
Conditions: Plaque Psoriasis
Interventions: BIOLOGICAL: Secukinumab|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Prospective, Randomized Controlled Trial of Stent Graft and Drug Coated Balloon Treatment for Recurrent Cephalic Arch Stenosis in Dysfunctional Arteriovenous-venous Fistula
Status: UNKNOWN
Conditions: Neointimal Hyperplasia|Dialysis Access Malfunction
Interventions: DEVICE: Paclitaxel Coated Balloon|DEVICE: Paclitaxel Coated Balloon and Stent Graft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single-dose Iloperidone Pharmacokinetics in Patients With Mild or Moderate Liver Disease, Compared to Healthy Volunteers
Status: COMPLETED
Conditions: Hepatic Impairment
Interventions: DRUG: Iloperidone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: A Study to Evaluate the Esophageal Stenosis Inhibition Effects of CLS2702C/CLS2702D After Endoscopic Submucosal Dissection (ESD) in Patients With Superficial Esophageal Cancer in the Steroid Administration Risk Group
Status: TERMINATED
Conditions: Superficial Esophageal Cancer
Interventions: COMBINATION_PRODUCT: CLS2702C/CLS2702D
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION