pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: CardioBreathApp vs IMT in Heart Failure
Status: RECRUITING
Conditions: Congestive Heart Failure
Interventions: DEVICE: Moment 1: IMT. Moment 2 CardioBreath.|DEVICE: Moment 1: CardioBreath and moment 2: IMT.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Look AHEAD: Action for Health in Diabetes
Status: COMPLETED
Conditions: Diabetes|Myocardial Infarction|Stroke|Kidney Diseases|Bone Diseases|Dyslipidemia
Interventions: BEHAVIORAL: Lifestyle Intervention|BEHAVIORAL: Diabetes Support and Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Treatment of Bronchopulmonary Dysplasia by Intratracheal Instillation of Mesenchymal Stem Cells
Status: UNKNOWN
Conditions: Safety Issues|Effect of Drugs
Interventions: OTHER: mesenchymal stem cells therapy|DRUG: 0.9% sodium chloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Epithesis Versus Prosthesis in Post-phalloplasty Transgender Patients.
Status: RECRUITING
Conditions: Transgenderism|Erectile Dysfunction|Prosthesis Durability|Gender Dysphoria|Sexual Dysfunction
Interventions: DEVICE: Usability and added value of device within sexual activity
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Non Invasive Brain Stimulation During Prolonged Experimental Pain
Status: COMPLETED
Conditions: Pain|Prolonged Experimental Pain
Interventions: DEVICE: Transcranial direct current stimulation (tDCS) of the resting state motor network
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Radiation Therapy With Sorafenib for TACE-Resistant Hepatocellular Carcinoma
Status: WITHDRAWN
Conditions: Hepatocellular Carcinoma|Hepatocellular Cancer|Hepatoma|Liver Cancer
Interventions: DRUG: Sorafenib|RADIATION: Conventional fractionation (2 Gy per day) external beam radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Follow up of Adults With Congenitally Malformed Hearts With Focus on Computer-Based Education and Psychosocial Support
Status: COMPLETED
Conditions: Adults With Congenitally Malformed Hearts
Interventions: OTHER: Physician and nurse consultation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Vascular Augmentation of Late-life Unremitted Depression (VALUeD)
Status: UNKNOWN
Conditions: Depression
Interventions: DRUG: Amlodipine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Motor Slowing and Its Lesion-related Correlates in Alzheimer's Disease
Status: RECRUITING
Conditions: Alzheimer Disease
Interventions: DEVICE: Brain MRI|OTHER: neuropsychological evaluation|BIOLOGICAL: Blood
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Randomized Study on the Evaluation of the Regular Practice of Standardized Postures Stretching Postural® in Secondary Prevention of Low Back Pains During Pregnancy.
Status: COMPLETED
Conditions: Lower Back Pain
Interventions: OTHER: Physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Role of Immature Myeloid Cells, Monocytes, Dentritic Cells and Neutrophils in Human Pregnancies as Markers for Mature Pregnancy and Spontaneous Labor
Status: UNKNOWN
Conditions: Parturition
Interventions: OTHER: Exposure: abundance of Immature Myeloid Cells counts in blood samples|OTHER: Exposure: abundance of Immature Dentritic Cells counts in blood samples|OTHER: Exposure: abundance of Immature monocytes counts in blood samples|OTHER: Exposure: abundance of Immature neutrophils counts in blood samples
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Combination Chemotherapy and Radiation Therapy in Treating Patients With Stage II or Stage III Non-small Cell Lung Cancer That Cannot Be Removed By Surgery
Status: UNKNOWN
Conditions: Lung Cancer
Interventions: DRUG: carboplatin|DRUG: paclitaxel|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Active Isolated Stretch and Post Facilitation Stretch on Hamstring Flexibility in Trans-tibial Amputees.
Status: COMPLETED
Conditions: Amputation
Interventions: OTHER: active isolated stretch|OTHER: Post Facilitation Stretch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Secukinumab in Patients With New Onset of Giant Cell Arteritis Who Are in Clinical Remission
Status: RECRUITING
Conditions: Giant Cell Arteritis
Interventions: BIOLOGICAL: Secukinumab 300 mg, s.c.|DRUG: Placebo to match Secukinumab, s.c.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical, Functional, Immunological and Genetic Factors on the Severity of the Course of Coronavirus Infection
Status: UNKNOWN
Conditions: Covid19|Corona Virus Infection
Interventions: DIAGNOSTIC_TEST: Clinical and functional analysis|DIAGNOSTIC_TEST: Neurological analysis|DIAGNOSTIC_TEST: Immunological analysis:|DIAGNOSTIC_TEST: Genetic analysis:
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Computational Design, Fabrication, and Evaluation of Optimized Patient-Specific Transtibial Prosthetic Sockets
Status: COMPLETED
Conditions: Amputation Stump
Interventions: DEVICE: Prosthetic socket for transtibial amputee
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Confirmatory Study of Fentanyl in Participants With Post-herpetic Neuralgia, Complex Regional Pain Syndrome or Postoperative Pain Syndrome
Status: COMPLETED
Conditions: Postherpetic Neuralgia|Complex Regional Pain Syndromes (CRPS)|Postoperative Pain
Interventions: DRUG: Fentanyl|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 2, Multicenter, Open-label Study of MEDI-551 in Adults With Relapsed or Refractory Chronic Lymphocytic Leukemia (CLL)
Status: COMPLETED
Conditions: Chronic Lymphocytic Leukemia (CLL)
Interventions: DRUG: Rituximab|DRUG: Bendamustine|DRUG: MEDI-551
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sequential Treatment With BELKYRA® Then Juvéderm® VOLUMA™ With Lidocaine for Overall Improvement in Jawline Contour
Status: COMPLETED
Conditions: Contour
Interventions: DRUG: BELKYRA®|DEVICE: Juvéderm® VOLUMA™ with Lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, and Immunogenicity of 3 Frozen ProQuad Consistency Lots in Healthy Children (V221-012)(COMPLETED)
Status: COMPLETED
Conditions: Measles|Mumps|Rubella|Varicella
Interventions: BIOLOGICAL: Measles, Mumps, Rubella and Varicella (Oka-Merck) Virus Vaccine Live|BIOLOGICAL: Comparator: Varivax|BIOLOGICAL: Comparator: M-M-R II
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Subepithelial Connective Tissue Graft Versus Amniotic Chorion Membrane for Peri-implant Mucosal Thickness Enhancement
Status: NOT_YET_RECRUITING
Conditions: Dental Implant
Interventions: PROCEDURE: implant placement and soft tissue augmentation with Autogenous Subepithelial Connective Tissue Graft or Amniotic Chorion Membrane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Determining the Benefits of Improving Communication in BPAP/CPAP Users
Status: COMPLETED
Conditions: Positive-Pressure Respiration|Communication
Interventions: DEVICE: F2S Communicator|OTHER: Non-functioning Communicator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Growing Right Onto Wellness (GROW): Changing Early Childhood Body Mass Index (BMI) Trajectories
Status: COMPLETED
Conditions: Overweight and Obesity|Childhood Obesity
Interventions: BEHAVIORAL: GROW Healthier|BEHAVIORAL: GROW Smarter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Nasacort AQ Hypothalamic-Pituitary-Adrenal (HPA) Axis Study in Children With Allergic Rhinitis
Status: COMPLETED
Conditions: Rhinitis, Allergic, Perennial and/or Seasonal
Interventions: DRUG: Placebo nasal spray|DRUG: Triamcinolone acetonide aqueous (TAA-AQ) nasal spray (NASACORT AQ)|DRUG: Placebo nasal spray|DRUG: Claritin® Syrup
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Kinetic Brain Exercises on Balance and Dual Task Activities in the Elderly
Status: COMPLETED
Conditions: Elderly|Exercise
Interventions: OTHER: Kinetic Brain Exercises and Core Stabilization Exercises|OTHER: Core Stabilization Exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Compare Captisol-Enabled (CE) Budesonide + Azelastine Nasal Solution and Rhinocort Aqua + Astelin in an Environmental Exposure Chamber (EEC) Study of Allergic Rhinitis
Status: COMPLETED
Conditions: Seasonal Allergic Rhinitis
Interventions: DRUG: Budesonide + Azelastine|DRUG: Budesonide + Azelastine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ergonomic Benefits From Robotically Assisted Laparoscopy for Hysterectomies and Other Indications
Status: RECRUITING
Conditions: Musculoskeletal Diseases or Conditions
Interventions: PROCEDURE: Robotically Assisted Laparoscopic Surgery|PROCEDURE: Conventional Laparoscopic Surgery
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Cheese on Cardiovascular Risk
Status: COMPLETED
Conditions: Hyperlipidemia
Interventions: OTHER: Dietary intervention: CHEESE (High cheese intake)|OTHER: Dietary intervention: MEAT (High Meat intake)|OTHER: Dietary intervention: CARB (High Carbohydrate intake)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Lavage With Super-Oxidized Solution for Secondary Peritonitis
Status: RECRUITING
Conditions: Peritonitis
Interventions: DEVICE: Super-oxidized solution (SOS)|DEVICE: Ringer's solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Parastomal Hernia Repair Utilizing the Retromuscular Sugarbaker Versus Keyhole Mesh Techniques
Status: COMPLETED
Conditions: Parastomal Hernia
Interventions: PROCEDURE: Sugarbaker technique for repairing parastomal hernia|PROCEDURE: Keyhole technique for repairing parastomal hernia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety, Tolerability and Immunogenicity of a Potential Enteric Fever Vaccine
Status: COMPLETED
Conditions: Enteric Fever
Interventions: BIOLOGICAL: ZH9PA and ZH9|BIOLOGICAL: Placebo|BIOLOGICAL: ZH9PA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Cord Blood Transplantation in Severe Aplastic Anemia
Status: COMPLETED
Conditions: Hereditary Diseases|Acquired Aplastic Anemia|Relapse|Absence of an HLA Identical Donor
Interventions: PROCEDURE: Cord Blood Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase II Trial of Proton Pump Inhibitors With Chemotherapy in Patients With Metastatic Head and Neck Cancer
Status: WITHDRAWN
Conditions: Cancer of Head and Neck
Interventions: DRUG: Omeprazole|DRUG: Carboplatin|DRUG: 5FU|DRUG: Paclitaxel|DRUG: Pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ipratropium Bromide/Salbutamol Delivered by the Respimat® Inhaler Compared to Ipratropium Bromide Respimat®, COMBIVENT® Inhalation Aerosol and Placebo in Adults With Chronic Obstructive Pulmonary Disease
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Ipratropium bromide / Salbutamol|DRUG: Placebo Inhalation solution|DRUG: Ipratropium bromide|DRUG: COMBIVENT Inhalation Aerosol|DRUG: Placebo Inhalation Aerosol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Circadian Phase Adjustment and Improvement of Metabolic Control in Night Shift Workers
Status: COMPLETED
Conditions: Sleep Disorders, Circadian Rhythm
Interventions: DRUG: Melatonin 2mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: To Evaluate Safety and Effectiveness of Transcatheter Aortic Valve System in Patients With Severe Aortic Insufficiency
Status: UNKNOWN
Conditions: Aortic Insufficiency
Interventions: DEVICE: Transcatheter Aortic Valve System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assess the Prognostic Usefulness of Flutemetamol (18F) Injection for Identifying Subjects With Amnestic Mild Cognitive Impairment Who Will Convert to Clinically Probable Alzheimer's Disease
Status: COMPLETED
Conditions: Mild Cognitive Impairment|Alzheimer's Disease
Interventions: DRUG: Flutemetamol (18F) Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Living Donor Liver Transplantation With Two Stage Hepatectomy for Patients With Isolated, Irresectable Colorectal Liver Metastases
Status: RECRUITING
Conditions: Colorectal Cancer Metastatic|Liver Metastases
Interventions: PROCEDURE: Living donor liver transplantation with two-staged hepatectomy.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Human Mucosal Immune Responses to Influenza Virus (SLVP026)
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Fluzone®|BIOLOGICAL: FluMist®
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Real-World Assessment of the Demographic, Clinical Characteristics and Outcomes of a Brazilian Cohort of Previously Untreated Extensive Stage-Small Cell Lung Cancer Receiving Durvalumab Combined With Platinum-Etoposide in (ES-SCLC) in Brazil
Status: RECRUITING
Conditions: Extensive-stage Small-cell Lung Cancer
Interventions: OTHER: Observational study
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The EPigenetic Consequences in Children of Intravenous vs Volatile Anaesthesia for Surgery (EPIVA)
Status: ACTIVE_NOT_RECRUITING
Conditions: Hypospadias|Anesthesia; Adverse Effect|Perioperative Complication|Pediatric ALL
Interventions: OTHER: Intravenous approach to anaesthetic maintenance|OTHER: Inhalational approach to anaesthetic maintenance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Aphakia Versus Pseudophakia in Children Under 2 Years Undergoing Bilateral Congenital Cataract Surgery
Status: COMPLETED
Conditions: Congenital Cataract
Interventions: DEVICE: Intraocular Lens (Acrysof IOL)|DEVICE: No IOL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 3 Study of Tanezumab for Chronic Low Back Pain
Status: COMPLETED
Conditions: Low Back Pain
Interventions: BIOLOGICAL: Placebo to Week 16; tanezumab 5mg SC|BIOLOGICAL: Placebo to Week 16, tanezumab 10 mg SC|BIOLOGICAL: Tanezumab 5 mg SC|BIOLOGICAL: Tanezumab 10 mg SC|BIOLOGICAL: Tramadol PR oral
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Characterization of Exposure From Topical Administration of [14C] Umeclidinium to Axilla or Palm of Healthy Male Subjects
Status: COMPLETED
Conditions: Hyperhidrosis
Interventions: DRUG: [14C]Umeclidinium 18.5 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Clinical Utility of Thrombelastography in Guiding Prophylaxis of Venous Thromboembolism Following Trauma
Status: COMPLETED
Conditions: Venous Thromboembolism
Interventions: DRUG: Dalteparin sodium|DRUG: Dalteparin sodium/aspirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of EDP1815 in Healthy Participants and Participants With Mild to Moderate Psoriasis and Atopic Dermatitis
Status: COMPLETED
Conditions: Psoriasis|Atopic Dermatitis
Interventions: DRUG: EDP1815|DRUG: Placebo oral capsule|DRUG: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Telerehabilitation With Trak in Knee and Shoulder Pathology: A Randomized Clinical Trial
Status: COMPLETED
Conditions: Shoulder Injury|Knee Injury
Interventions: DEVICE: Trak-Physio knee condition|DEVICE: Trak-Physio in shoulder condition|OTHER: Knee conventional rehabilitation program|OTHER: Shoulder conventional rehabilitation program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prophylaxis With Single Versus Five Dose of Antibiotic Therapy as Treatment of Patients With Gangrenous Acute Appendicitis
Status: COMPLETED
Conditions: Gangrenous Appendicitis
Interventions: OTHER: prophylaxis|OTHER: therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Research Study to See How Semaglutide Works Compared to Placebo in People With Type 2 Diabetes and Chronic Kidney Disease
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Semaglutide|DRUG: Placebo (semaglutide)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Tipranavir (With Ritonavir) Capsule and Liquid Formulation on Cytochrome P450 and P-glycoprotein Activity in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Tipranavir capsule|DRUG: Tipranavir solution|DRUG: Ritonavir capsule|DRUG: Caffeine|DRUG: Warfarin sodium|DRUG: Vitamin K|DRUG: Omeprazole|DRUG: Dextromethorphan hydrobromide|DRUG: Midazolam injection|DRUG: Midazolam oral solution|DRUG: Digoxin tablet|DRUG: Digoxin injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of His Bundle Pacing in Treatment of Slow Arrhythmia on Function of Left Atrial and Ventricle
Status: COMPLETED
Conditions: Slow Arrhythmia|His Bundle Pacing|Function of Left Atrial and Ventricle
Interventions: DEVICE: Dual Chamber Pacemaker|DEVICE: His Bundle Pacemaker
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Exoskeleton Robotic Training Device on Upper Extremity in Brain Injury Patients
Status: COMPLETED
Conditions: Chronic Stroke
Interventions: BEHAVIORAL: Robotic-assisted intervention|BEHAVIORAL: Conventional rehabilitation intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of GlaxoSmithKline Biologicals' GSK2202083A Vaccine in Healthy Infants
Status: COMPLETED
Conditions: Tetanus|Hepatitis B|Haemophilus Influenzae Type b|Poliomyelitis|Acellular Pertussis|Diphtheria|Neisseria Meningitidis
Interventions: BIOLOGICAL: GSK2202083A vaccine|BIOLOGICAL: Prevenar 13®|BIOLOGICAL: Infanrix hexa™|BIOLOGICAL: Menjugate®|BIOLOGICAL: Rotarix™
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Computer Delivered Community Reinforcement Approach (CRA) (Bup II)
Status: COMPLETED
Conditions: Opiate Addiction
Interventions: DRUG: Suboxone|BEHAVIORAL: CRA|BEHAVIORAL: Therapy|BEHAVIORAL: CM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Walnut Oral Immunotherapy for Tree Nut Allergy
Status: COMPLETED
Conditions: Tree Nut Allergy
Interventions: DRUG: Walnut Protein Powder|DRUG: Oat Powder (placebo)|DRUG: Open-label Walnut Protein Powder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study in Healthy Men and Women to Test Whether BI 1569912 Influences the Amount of Repaglinide, Midazolam and Bupropion in the Blood
Status: ACTIVE_NOT_RECRUITING
Conditions: Healthy
Interventions: DRUG: BI 1569912|DRUG: repaglinide|DRUG: midazolam|DRUG: bupropion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pregabalin Versus Dexmedetomidine for Delirium Treatment After Coronary Artery Bypass Grafting
Status: RECRUITING
Conditions: Pregabalin|Delirium Treatment|Coronary Artery Bypass Grafting|Dexmedetomidine
Interventions: DRUG: Pregabalin|DRUG: Dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Double-blind, Placebo-controlled Comparative Study and Open-label Extension Study to Confirm the Efficacy and Safety of E2020 in Subjects With Down Syndrome Having Regression Symptoms and Disabled Activities of Daily Living.
Status: COMPLETED
Conditions: Down Syndrome
Interventions: DRUG: E2020-Donepezil hydrochloride|DRUG: E2020-Donepezil hydrochloride|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of TG103 Injection in Overweight/Obese Subjects With Type 2 Diabetes
Status: UNKNOWN
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: TG103|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Upper Airway's Pressure Drop Analyses After Mandibular Advancement and Maxillary Expansion
Status: RECRUITING
Conditions: Apnea|Airway Obstruction, Nasal|Mandible Small|Maxillary Hypoplasia
Interventions: OTHER: Twin block then Hyrax|OTHER: Hyrax then Twin block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Visual Outcomes of Subjects Bilaterally Implanted With ReSTOR Aspheric +4 vs. Tecnis or Acri.LISA
Status: COMPLETED
Conditions: Cataract
Interventions: DEVICE: ReSTOR|DEVICE: Tecnis|DEVICE: Acri.LISA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Assessing the Effectiveness of BFA as a Non-pharmacologic Pain Management Intervention: A Randomised Sham Controlled Study
Status: RECRUITING
Conditions: Assessing the Effectiveness of BFA as a Non-pharmacologic Pain Management Intervention: A Randomised Sham Controlled Study
Interventions: OTHER: accupunture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of RIC on Cerebral Autoregulation in Patients Undergoing Cerebrovascular Stent Implantation
Status: RECRUITING
Conditions: Remote Ischemic Conditioning
Interventions: PROCEDURE: Remote ischemic conditioning|PROCEDURE: Sham remote ischemic conditioning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Effect of High Fat Meal and Increased Gastric pH on the Bioavailability of an Extended Release Formulation of BMS-663068 in Healthy Subjects
Status: COMPLETED
Conditions: Infection, Human Immunodeficiency Virus
Interventions: DRUG: BMS-663068
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: |Primary Purpose: OTHER
Clinical trial: Celecoxib, Leucovorin, Fluorouracil, and Oxaliplatin in Treating Patients With Metastatic Colorectal Cancer
Status: UNKNOWN
Conditions: Colorectal Cancer
Interventions: DRUG: celecoxib|DRUG: fluorouracil|DRUG: leucovorin calcium|DRUG: oxaliplatin|PROCEDURE: adjuvant therapy|PROCEDURE: conventional surgery|PROCEDURE: neoadjuvant therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Frailty in Elderly Patients Receiving Surgical or Percutaneous Procedures for Valvular Disorders
Status: ACTIVE_NOT_RECRUITING
Conditions: Age Problem|Aortic Valve Disease|Mitral Valve Disease
Interventions: OTHER: frailty evaluation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Graston Technique on Planter Thickness in Patients With Planter Fasciitis
Status: NOT_YET_RECRUITING
Conditions: Plantar Fascitis
Interventions: OTHER: Garston technique|OTHER: exercise program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility Study on Parents Skill Training Program for Reducing Parental Distress and Disruptive Behavior of Their Children With Autism Spectrum Disorder (ASD)
Status: UNKNOWN
Conditions: Autism Spectrum Disorder|Disruptive Behaviours
Interventions: BEHAVIORAL: Parent Training for Disruptive Behaviours
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Differential Effect of Four Mindfulness Exercises
Status: COMPLETED
Conditions: Well-being|Depression|Anxiety
Interventions: BEHAVIORAL: Control group relaxation techniques|BEHAVIORAL: Loving-kindness meditation|BEHAVIORAL: Body scan|BEHAVIORAL: Sitting practice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acute Exposure to High Altitude on Exercise Capacity
Status: COMPLETED
Conditions: Pulmonary Hypertension
Interventions: OTHER: Assessment at Low Altitude (470m above sea level)|OTHER: Exposure to High Altitude (2500m above sea level)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Sino-nasal Inhalation of Colistin in Patients With Cystic Fibrosis and Pseudomonas Aeruginosa Colonization
Status: COMPLETED
Conditions: Cystic Fibrosis|Pseudomonas Aeruginosa
Interventions: DRUG: Colistin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nucleipark:High Field MR Imaging (7T and 3T) of the Brainstem, the Deep Nuclei and Their Connections in the Parkinsonian Syndromes. Applications to Prognosis, Pathophysiology and Improvement of Therapeutic Strategies
Status: UNKNOWN
Conditions: Parkinson's Disease|MRI
Interventions: OTHER: 3T and 7T MR imaging
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: An Exploratory Study of Esketamine in Patients After Thoracoscopic Surgery
Status: COMPLETED
Conditions: Esketamine|Thoracoscopic Surgery
Interventions: DRUG: Esketamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Spinal Cord sTimulation thEraPy for Parkinson's Disease Patients With Gait Problems
Status: UNKNOWN
Conditions: Parkinson Disease|Gait Disorders, Neurologic|Fall Injury
Interventions: DEVICE: Spinal Cord Stimulator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I Study of LBH589 (Panobinostat) in Combination With External Beam Radiotherapy for the Treatment of Prostate Cancer, Esophageal Cancer and Head and Neck Cancer
Status: COMPLETED
Conditions: Prostate Cancer|Head & Neck Cancer|Esophageal Cancer
Interventions: DRUG: panobinostat
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Application of Intrahepatic Arterial Infusion Chemotherapy for Patients With High Risk of Liver Metastases After Pancreatic Cancer Surgery
Status: UNKNOWN
Conditions: Pancreatic Ductal Adenocarcinoma|Who Have High CTCs Count in Portal Venous Blood|Liver Metastases
Interventions: DEVICE: Intrahepatic Arterial Infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: KL₄Surfactant Treatment in Patients With ARDS
Status: TERMINATED
Conditions: Acute Respiratory Distress Syndrome
Interventions: DRUG: A.1 Lucinactant|OTHER: B.3 SoC|DRUG: A.2 Lucinactant|DRUG: A.3 Lucinactant|DRUG: A.4 Lucinactant|DRUG: B.1 Lucinactant|DRUG: B.2 Lucinactant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: At Home Study of a Zone-Model Predictive Control (MPC) Controller and a Health Monitoring System (HMS) With the Diabetes Assistant (DiAs) System and Run-to-Run Adaptation
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus
Interventions: DEVICE: CGM and Insulin Pump|DEVICE: Closed-Loop Control System
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evolocumab Plus Ezetimibe in High Risk Haemodialized Statin Intolerant Patients
Status: UNKNOWN
Conditions: Hypercholesterolemia|Chronic Kidney Disease Requiring Chronic Dialysis
Interventions: DRUG: Evolocumab|DRUG: Placebo|DRUG: Ezetimibe
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cholecalciferol and Calcium Carbonate in Treating Patients With Colon Cancer That Has Been Removed by Surgery
Status: TERMINATED
Conditions: Colorectal Cancer
Interventions: DIETARY_SUPPLEMENT: calcium carbonate|DIETARY_SUPPLEMENT: cholecalciferol|OTHER: immunohistochemistry staining method|OTHER: laboratory biomarker analysis|OTHER: pharmacological study|PROCEDURE: biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Feasibility of Hyivy Device Post-Radiation for Pelvic Malignancies
Status: NOT_YET_RECRUITING
Conditions: Vaginal Stenosis|Radiation Therapy|Cancer|Pelvic Pain|Pelvic Cancer
Interventions: DEVICE: Hyivy Intravaginal Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: E-cigarettes and Cardiovascular Function
Status: COMPLETED
Conditions: Smoking Cessation|Cardiovascular Diseases|Microcirculation|Macrocirculation
Interventions: OTHER: Electronic Cigarette and behavioural change support.|OTHER: Nicotine-Free Electronic Cigarette and behavioural change support.|OTHER: Nicotine Replacement Therapy and behavioural change support.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Piezosurgery and Conventional Rotary Instruments on Third Molar Surgery
Status: COMPLETED
Conditions: Impacted Third Molar Tooth
Interventions: DEVICE: Piezosurgery|DEVICE: Conventional burs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Insulin Glargine in Patients With Type 2 Diabetes With Inadequate Control on DPP-4 Inhibitor Therapy
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: INSULIN GLARGINE|DRUG: Metformin|DRUG: DPP-4 inhibitor|DRUG: Sulphonylurea
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tisagenlecleucel vs Blinatumomab or Inotuzumab for Patients With Relapsed/Refractory B-cell Precursor Acute Lymphoblastic Leukemia
Status: WITHDRAWN
Conditions: Acute Lymphoblastic Leukemia
Interventions: BIOLOGICAL: Tisagenlecleucel|DRUG: Blinatumomab|DRUG: Inotuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Comparing Nitrofurantoin to Fosfomycin for Acute Urinary Tract Infection in Women
Status: UNKNOWN
Conditions: Urinary Tract Infections|Cystitis
Interventions: DRUG: nitrofurantoin|DRUG: fosfomycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Oral or Intravenous Thiazides vs Tolvaptan in Diuretic Resistant Decompensated Heart Failure
Status: COMPLETED
Conditions: Heart Failure
Interventions: DRUG: tolvaptan|DRUG: Chlorothiazide|DRUG: Metolazone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: VA111913 Dysmenorrhoea Efficacy and Safety Proof of Concept
Status: COMPLETED
Conditions: Primary Dysmenorrhea
Interventions: DRUG: VA111913 TS and placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of Hemospray Plus Epinephrine Injection Versus Endoscopic Hemoclip
Status: UNKNOWN
Conditions: Upper Gastrointestinal Bleeding
Interventions: DEVICE: Metal clips|DRUG: Hemospray|PROCEDURE: Endoscopy Exam|DRUG: Adrenaline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: An Experimental Medicine Decipher of a Minimum Correlate of Cellular Immunity
Status: RECRUITING
Conditions: Infectious Disease|Yellow Fever|Japanese Encephalitis|Viral Infection
Interventions: BIOLOGICAL: Stamaril|BIOLOGICAL: Imojev|BIOLOGICAL: Ixiaro
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Prospective, Randomized Controlled Trial on Perioperative Pregabalin to Reduce Late-onset CRPS After TKA
Status: COMPLETED
Conditions: CRPS
Interventions: DRUG: pregabalin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Low-dose rhIL-2 in Patients With Recently-diagnosed Type 1 Diabetes
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: DRUG: rhIL-2|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Intraperitoneal Triferic in Patients on Chronic Peritoneal Dialysis
Status: COMPLETED
Conditions: Peritoneal Dialysis (PD)|Anemia|Chronic Kidney Disease
Interventions: DRUG: Triferic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy in Treating Infants With Newly Diagnosed Neuroblastoma Who Are Undergoing Surgery With or Without Autologous Bone Marrow or Peripheral Stem Cell Transplant
Status: UNKNOWN
Conditions: Neuroblastoma
Interventions: BIOLOGICAL: filgrastim|DRUG: busulfan|DRUG: carboplatin|DRUG: cyclophosphamide|DRUG: doxorubicin hydrochloride|DRUG: etoposide phosphate|DRUG: melphalan|DRUG: vincristine sulfate|PROCEDURE: autologous bone marrow transplantation|PROCEDURE: bone marrow ablation with stem cell support|PROCEDURE: conventional surgery|PROCEDURE: peripheral blood stem cell transplantation|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low Doses of Ketamine and Postoperative Quality of Recovery
Status: COMPLETED
Conditions: Postoperative Pain|Postoperative Nausea and Vomiting
Interventions: DRUG: Ketamine 0.4 mg/kg|DRUG: Normal saline|DRUG: Ketamine 0.2 mg/kg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Gelatin Sponge VS PTFE Membrane for Socket Sealing After Immediate Implant Placement
Status: COMPLETED
Conditions: Dental Implant Failed|Teeth Absent|Soft Tissue Injuries
Interventions: DEVICE: PTFE application|DEVICE: Gelatin sponge
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Magnólia Nasal Gel in the Treatment of Allergic Rhinitis
Status: WITHDRAWN
Conditions: Allergic Rhinitis
Interventions: DRUG: MAGNÓLIA NASAL GEL|DRUG: MOMETASONE FUROATE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Controlling Post-extraction Complications of Impacted Mandibular Third Molar
Status: COMPLETED
Conditions: Preventing Postextraction Complication
Interventions: DRUG: Normal saline|DRUG: Hyaluronic acid|DRUG: Methylprednisolone|DRUG: Methylprednisolone and Hyaluronic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial to Evaluate the Safety and Immunogenicity of a Placental Malaria Vaccine Candidate (PRIMVAC ) in Healthy Adults
Status: COMPLETED
Conditions: Malaria
Interventions: BIOLOGICAL: PRIMVAC|BIOLOGICAL: GLA-SE|BIOLOGICAL: Alhydrogel|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Patient Reported Outcomes (PRO) After Total Knee Arthroplasty (TKA) Under Spinal Anesthesia
Status: TERMINATED
Conditions: Knee Injuries
Interventions: PROCEDURE: Spinal Surgery|DEVICE: Verasense Knee System device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RCT of Iodine-containing MNPs vs Oral Iodized Oil to Prevent Iodine Deficiency in Weaning Infants
Status: WITHDRAWN
Conditions: Iodine Deficiency Disorders
Interventions: DIETARY_SUPPLEMENT: MNP90|DIETARY_SUPPLEMENT: MNP45|DIETARY_SUPPLEMENT: IODISED OIL|DIETARY_SUPPLEMENT: INERT OIL|DIETARY_SUPPLEMENT: INERT MNP|DIETARY_SUPPLEMENT: NON-IODISED MNP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Analgesic Efficacy of Hypnosis and Virtual Reality in Repetitive Pain Care
Status: RECRUITING
Conditions: Pain
Interventions: OTHER: Management pain with distraction methods ABC|OTHER: Management pain with distraction methods BCA|OTHER: Management pain with distraction methods CAB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study in the Treatment of HCC With a Radiopaque (RO) Bead (LC Bead LUMI™) Loaded With Doxorubicin
Status: WITHDRAWN
Conditions: Hepatocellular Carcinoma (HCC)
Interventions: DEVICE: LC Bead LUMI™ (Radiopaque (RO) Bead) loaded with doxorubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Skin Cancer and Hyperthermia and Radiotherapy
Status: NOT_YET_RECRUITING
Conditions: Basal Cell Carcinoma|Squamous Cell Carcinoma Skin|Non-melanoma Skin Cancer
Interventions: COMBINATION_PRODUCT: Water-filtered infrared-A-hyperthermia (wIRA) hyperthermia combined|RADIATION: Radiotherapy (RT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Opioid Free Anesthesia and Bariatric Surgery
Status: RECRUITING
Conditions: Postoperative Quality of Recovery
Interventions: COMBINATION_PRODUCT: Opioid Free Total Intravenous Anesthesia|COMBINATION_PRODUCT: Total Intravenous anesthesia with opioid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Safety of Lactobacillus Rhamnosus GG ATCC 53103 (LGG) in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: BIOLOGICAL: Lactobacillus rhamnosus GG ATCC 53103|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose:
Clinical trial: Inhibitory Mechanisms of Negative Urgency in Adolescent Suicidal Behavior
Status: RECRUITING
Conditions: Suicidal Behavior|Suicidal Ideation|Negative Urgency|Cortical Inhibition|Depression
Interventions: OTHER: Single-/paired-pulse transcranial magnetic stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Ledipasvir/Sofosbuvir Fixed-Dose Combination ± Ribavirin in Participants With Chronic Genotype 1 HCV Who Participated in a Prior Gilead-Sponsored HCV Treatment Study
Status: COMPLETED
Conditions: HCV Infection
Interventions: DRUG: LDV/SOF|DRUG: RBV
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability of Etanercept in Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: BIOLOGICAL: Etanercept|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Retrieval Study and Histological Examination Of A Hip Femoral Components With Hydroxyapatite Coatings
Status: TERMINATED
Conditions: Femoral Neck Fractures
Interventions: DEVICE: Hip stem with plasma sprayed porous Ti 6Al4V alloy + plasma sprayed HA|DEVICE: Hip stem with plasma spayed porous Titanium 6Al4V alloy + Bonemaster HA|DEVICE: Hip stem with Interloc Titanium surface + Bonemaster H.A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endoscopic Guided PCNL Versus Standard PCNL
Status: UNKNOWN
Conditions: Stones, Kidney
Interventions: PROCEDURE: Endoscopic compbined guided PCNL|PROCEDURE: Standard PCNL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dose-Finding Study Of CP-675,206 And SU011248 In Patients With Metastatic Renal Cell Carcinoma
Status: COMPLETED
Conditions: Carcinoma, Renal Cell
Interventions: DRUG: CP-675,206|DRUG: SU011248|DRUG: CP-675,206|DRUG: SU011248
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Safety and Effectiveness of Apixaban in Preventing Blood Clots in Children With Leukemia Who Have a Central Venous Catheter and Are Treated With Asparaginase
Status: COMPLETED
Conditions: Lymphoma|Acute Lymphoblastic Leukemia
Interventions: DRUG: Apixaban|OTHER: No systemic anticoagulant prophylaxis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION