pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Enucleation of Pancreatic Tumor by Blocking Abdominal Trunk and Superior Mesenteric Artery
Status: RECRUITING
Conditions: Tumor of Pancreas|Surgical Blood Loss
Interventions: PROCEDURE: blocking both the abdominal trunk and superior mesenteric artery in the pancreatic enucleation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Short-term Intensive Chemoresection Versus Standard Adjuvant Intravesical Instillations in NMIBC
Status: ACTIVE_NOT_RECRUITING
Conditions: Bladder Cancer
Interventions: DRUG: Mitomycin c
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Precursor B Cell Acute Lymphoblastic Leukemia (B-ALL) Treated With Autologous T Cells Genetically Targeted to the B Cell Specific Antigen CD19
Status: ACTIVE_NOT_RECRUITING
Conditions: Leukemia|Acute Lymphoblastic Leukemia
Interventions: BIOLOGICAL: gene-modified T cells targeted
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of X-82 in Patients With Wet AMD
Status: COMPLETED
Conditions: Exudative Macular Degeneration
Interventions: DRUG: X-82 oral|DRUG: ranibizumab (Lucentis)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevelance of Uterine Vein and Uterine Vein System Variations
Status: RECRUITING
Conditions: Uterine Vein Injury Left|Uterine Vein Injury Right
Interventions: OTHER: Prevelance of Uterine Vein and Uterine Vein System Variations (anatomical study)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Dasatinib for the Prevention of Oxaliplatin-Induced Neuropathy in Patients With Metastatic Gastrointestinal Cancer Receiving FOLFOX Chemotherapy With or Without Bevacizumab
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Colorectal Carcinoma|Metastatic Colorectal Carcinoma|Stage IV Colorectal Cancer AJCC v8|Stage IVA Colorectal Cancer AJCC v8|Stage IVB Colorectal Cancer AJCC v8|Stage IVC Colorectal Cancer AJCC v8|Stage II Colon Cancer|Stage II Rectal Cancer|Stage III Colon Cancer|Stage III Rectal Cancer|Esophageal Cancer|Pancreatic Cancer|Bile Duct Cancer|Gastric Cancer|Gall Bladder Cancer|Small Bowel Adenocarcinoma
Interventions: BIOLOGICAL: Bevacizumab|DRUG: Dasatinib|DRUG: Fluorouracil|DRUG: Leucovorin|DRUG: Leucovorin Calcium|DRUG: Oxaliplatin|OTHER: Quality-of-Life Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Stress Urinary Incontinence Study to Assess Safety and Efficacy of Muvon's Muscle Precursor Cell Therapy
Status: RECRUITING
Conditions: Female Stress Urinary Incontinence
Interventions: BIOLOGICAL: autologous muscle precursor cells
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Association Between S-LAAO and Adverse Cardiovascular Events Among Patients Undergoing Coronary Artery Bypass Grafting.
Status: UNKNOWN
Conditions: Heart Surgery
Interventions: PROCEDURE: Left atrial appendage occlusion surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: IN Midazolam vs IN Dexmedetomidine vs IN Ketamine During Minimal Procedures in Pediatric ED
Status: RECRUITING
Conditions: Laceration of Skin|Anxiety|Discharge Time
Interventions: DRUG: Intranasal Midazolam|DRUG: Intranasal Dexmedetomidine|DRUG: Intranasal Ketamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: COVID-19 Pandemic Burden in Severe Mental Disease Patients
Status: COMPLETED
Conditions: Psychological Distress|COVID|Severe Mental Disorder
Interventions: OTHER: PSS (Perceived Stress Scale)|OTHER: GAD-7 (7-item Generalized Anxiety Disorder)|OTHER: PHQ-9 (9-item Patient Health Questionnaire)|OTHER: SPEQ (Specific Psychotic Experiences Questionnaire) - Paranoia and Grandiosity Subscales|OTHER: Zaritt Burden Interview
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of Creon (Pancrelipase) in Resected and Non-resected Pancreatic Cancer Participants With Exocrine Pancreatic Insufficiency (EPI)
Status: TERMINATED
Conditions: Exocrine Pancreatic Insufficiency (EPI)
Interventions: DRUG: Pancrelipase|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Melatonin on Sleep Patterns of Resident Trainees During Night Float Shift
Status: RECRUITING
Conditions: Sleep Disorders, Circadian Rhythm
Interventions: DIETARY_SUPPLEMENT: Melatonin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Hydroxychloroquine Sulfate in the Treatment of Recurrent Spontaneous Abortion With Antiphospholipid Syndrome
Status: UNKNOWN
Conditions: Antiphospholipid Syndrome|Recurrent Miscarriage
Interventions: DRUG: Hydroxychloroquine Sulfate Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Measuring the Plasma Clearance of Iohexol to Estimate Glomerular Filtration Rate in Intensive Care Unit Patients: Preliminary Feasibility Study
Status: COMPLETED
Conditions: Acute Circulatory Failure
Interventions: DRUG: Iohexol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Relationship Between Triceps Skinfold and Overall Survival of Pancreas, Bile Duct, Gallbladder Cancer
Status: RECRUITING
Conditions: Pancreas Cancer|Cholangiocarcinoma|Gallbladder Cancer
Interventions: OTHER: Measurement of triceps skinfold thickness
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: SHR-1701 in Combination With Chemotherapy and Radiotherapy in Locally Advanced Rectal Cancer
Status: RECRUITING
Conditions: Locally Advanced Rectal Cancer
Interventions: DRUG: SHR-1701；Capecitabine；Oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy/Safety Study to Explore a New Revised Topical Formulation in Atopic Dermatitis
Status: COMPLETED
Conditions: Dermatitis, Atopic
Interventions: DEVICE: Phoenix II (BAY81-2996)|DEVICE: Phoenix I (BAY81-2996)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Robotic-assisted and Laparoscopic Right Colectomy Study - Intracorporeal vs. Extracorporeal Anastomoses
Status: COMPLETED
Conditions: Benign Right Colon Disease|Malignant Right Colon Disease
Interventions: PROCEDURE: Right Colectomy with Intracorporeal Anastomosis|PROCEDURE: Right Colectomy with Extracorporeal Anastomosis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Which is Better Piezosurgery or Piezosurgery With Laser in Accelerating Orthodontic Tooth Movement
Status: COMPLETED
Conditions: Angle Class II
Interventions: PROCEDURE: Piezosurgery and GaALAs diode laser|PROCEDURE: Piezosurgery|OTHER: Fixed orthodontic appliance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability Study of PCI-32765 in B Cell Lymphoma and Chronic Lymphocytic Leukemia
Status: COMPLETED
Conditions: B-cell Chronic Lymphocytic Leukemia|Small Lymphocytic Lymphoma|Diffuse Well-differentiated Lymphocytic Lymphoma|B Cell Lymphoma|Follicular Lymphoma|Mantle Cell Lymphoma|Non-Hodgkin's Lymphoma|Waldenstrom Macroglobulinemia|Burkitt Lymphoma|B-Cell Diffuse Lymphoma
Interventions: DRUG: PCI-32765
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Calculating Blood Volume by Dilution of Hemoglobin - Pilot Study
Status: COMPLETED
Conditions: Determine Validity of Concept of Using Hemoglobin Dilution to Assess/Measure Blood Volume.
Interventions: DRUG: Blood Volume Dilution
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Simple Decompression Versus Anterior Transposition of the Ulnar Nerve
Status: COMPLETED
Conditions: Humeral Fractures|Ulnar Nerve Compression
Interventions: PROCEDURE: Simple decompression|PROCEDURE: anterior subcutaneous transposition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intra-operative Lidocaine Infusion in Preventing CPSP Post VATs
Status: UNKNOWN
Conditions: Chronic Pain|Acute Pain|Neuralgia
Interventions: DRUG: Lidocaine|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Lung Recruitment Manoeuvre in Morbidly Obese Patients Underdoing Laparoscopic Bariatric Surgery
Status: RECRUITING
Conditions: Bariatric Surgery|Obesity, Morbid
Interventions: DEVICE: Lung Recruitment Conventional|DEVICE: Lung Recruitment Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Efficacy Study for MG-7-DC Vaccine in Gastric Cancer Treatment
Status: UNKNOWN
Conditions: Gastric Cancer
Interventions: BIOLOGICAL: DC vaccine|BIOLOGICAL: CTL|DRUG: Sintilimab Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Automated Myocardial Performance Index Using Samsung HERA W10
Status: TERMINATED
Conditions: Twin to Twin Transfusion Syndrome|Congenital Diaphragmatic Hernia|Neural Tube Defects|Lower Urinary Tract Infection
Interventions: DEVICE: Automated Myocardial Performance Index (MPI)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study to Evaluate Clinical Efficacy and Safety of Bio Mineral Toothpaste in Patients With Mild Periodontitis
Status: COMPLETED
Conditions: Periodontitis
Interventions: OTHER: Bio Mineral toothpaste|OTHER: Perio Total Care toothpaste
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Determining the Effectiveness of Sexual Health and Development Education for Children With Intellectual Disability
Status: UNKNOWN
Conditions: Child Behavior Problem|Intellectual Disability|Sexuality
Interventions: BEHAVIORAL: Sexual Health and Development Education for Children With Intellectual Disability
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Pharmacokinetic Interaction Between SSP-004184 (SPD602) and Midazolam in Healthy Adult Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Midazolam|DRUG: SSP-004184SS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Efficacy of the Act of Urination to Relief the Pain During Flexible Cystoscopy Procedure.
Status: UNKNOWN
Conditions: Hematuria|Bladder Ca|Bladder Stone|Urologic Diseases
Interventions: PROCEDURE: Instruction to urinate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Colon Adjuvant Chemotherapy Based on Evaluation of Residual Disease
Status: RECRUITING
Conditions: Stage III Colon Cancer
Interventions: DEVICE: Signatera test|DRUG: mFOLFOX6 3-6 month|DRUG: CAPOX 3 month|DRUG: mFOLFIRINOX|DRUG: mFOLFOX6 6 month|DRUG: CAPOX 6 month
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multi Modal Brain Monitoring and Cardiac Surgery
Status: UNKNOWN
Conditions: Intraoperative Neurophysiological Monitoring
Interventions: DEVICE: Nearinfrared Spectroscopy (NIRS)|DEVICE: Transcranial Doppler (TCD)|DEVICE: Bispectral index (BIS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Evaluation Of The Efficacy Of Four Different Non-invasive Ventilation Modes Performed In The Delivery Room
Status: UNKNOWN
Conditions: Respiratory Disease|Respiratory Insufficiency
Interventions: DEVICE: HHHFNC|DEVICE: NCPAP|DEVICE: NIPPV|DEVICE: NHFO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: SJG-136 in Treating Patients With Relapsed or Refractory Acute Leukemia, Myelodysplastic Syndromes, Blastic Phase Chronic Myelogenous Leukemia, or Chronic Lymphocytic Leukemia
Status: TERMINATED
Conditions: Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities|Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)|Adult Acute Myeloid Leukemia With t(15;17)(q22;q12)|Adult Acute Myeloid Leukemia With t(16;16)(p13;q22)|Adult Acute Myeloid Leukemia With t(8;21)(q22;q22)|Blastic Phase Chronic Myelogenous Leukemia|de Novo Myelodysplastic Syndromes|Previously Treated Myelodysplastic Syndromes|Recurrent Adult Acute Lymphoblastic Leukemia|Recurrent Adult Acute Myeloid Leukemia|Refractory Chronic Lymphocytic Leukemia|Relapsing Chronic Myelogenous Leukemia|Secondary Acute Myeloid Leukemia|Secondary Myelodysplastic Syndromes
Interventions: DRUG: SJG-136
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adherence Assessment With Travalert Dosing Aid
Status: COMPLETED
Conditions: Open-angle Glaucoma|Ocular Hypertension
Interventions: DRUG: Travoprost 0.004%/timolol 0.5% fixed combination eye drops (DuoTrav)|DRUG: Travoprost 0.004% eye drops|DRUG: Timolol 0.05% eye drops|DEVICE: Travalert Dosing Aid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: LIver TrAnspLantation for Non-resectable Peri-HIlar cholangioCArcinoma (LITALHICA)
Status: RECRUITING
Conditions: Perihilar Cholangiocarcinoma
Interventions: PROCEDURE: Liver transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility Pilot Study to Evaluate the Safety and Performance of the MEX-CD1 Medical Device in ACLF
Status: RECRUITING
Conditions: Acute on Chronic Liver Failure|Multiple Organ Failure
Interventions: DEVICE: MEX-CD1 Dialysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Local Anaesthetic Day-care Haemorrhoidectomy Challenges Traditional Concepts - a Randomised Controlled Trial
Status: COMPLETED
Conditions: Hemorrhoids
Interventions: PROCEDURE: Hemorrhoidectomy|PROCEDURE: Hemorrhoidectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: fMRI Analysis of Aging and Awareness in Conditioning
Status: ACTIVE_NOT_RECRUITING
Conditions: Transcranial Direct Current Stimulation
Interventions: DEVICE: transcranial direct current stimulation|DEVICE: sham transcranial direct current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of the Effects of Lidocaine and Articaine Used for Buccal Infiltration and Supplemental Palatinal Infiltration Anesthesia in Teeth With Irreversible Pulpitis
Status: COMPLETED
Conditions: Fist and Second Molars With ırreversible Pulpitis
Interventions: PROCEDURE: Anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pressure-controlled Intermittent Coronary Sinus Occlusion (PiCSO) in Acute Myocardial Infarction
Status: COMPLETED
Conditions: STEMI|Anterior MI
Interventions: DEVICE: PiCSO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Building Strength Through Rehabilitation for Heart Failure Patients (BISTRO-STUDY)
Status: TERMINATED
Conditions: Heart Failure
Interventions: DEVICE: Transcutaneous electrical stimulation|DEVICE: Neuromuscular electrical stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Randomized Trial of Fibrinogen in Trauma Haemorrhage
Status: COMPLETED
Conditions: Trauma|Haemorrhage
Interventions: DRUG: Fibrinogen|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Association Between VEGF-C and miRNA and Clinical Non-small Cell Lung Cancer and Esophagus Squamous Cell Carcinoma
Status: UNKNOWN
Conditions: VEGFC Protein in Serum|VEGFC Protein in Non Small Cell Lung Cancer|VEGFC Protein in ESCC|CTTN Protein in ESCC|miR326 in ESCC and Non Small Cell Lung Cancer
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: PHMB-based Antiseptic Use in Full-thickness Surgical Wounds
Status: COMPLETED
Conditions: Surgical Site Infections
Interventions: DEVICE: Applying Prontosan antiseptic solution to tie-over dressings|DEVICE: Applying Placebo to tie-over dressings
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: French National Registry of Rare Peritoneal Surface Malignancies
Status: UNKNOWN
Conditions: Rare Peritoneal Surface Malignancies|Pseudomyxoma Peritonei|Peritoneal Mesothelioma|Desmoplastic Small Round Cell Tumor|Psammocarcinoma|Primary Peritoneal Serous Carcinoma|Diffuse Peritoneal Leiomyomatosis|Appendiceal Mucinous Neoplasms
Interventions: OTHER: Non interventional
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Prostate Cancer Detection Rate of Targeted Biopsies With PCaVision
Status: RECRUITING
Conditions: Prostate Cancer
Interventions: DIAGNOSTIC_TEST: 3D multi-parametric ultrasound targeted biopsy pathway using PcaVision|DIAGNOSTIC_TEST: MRI targeted biopsy pathway
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Magnesium Balance of Citrate-based Continuous Venovenous Hemofiltration, Effect of Citrate Dose.
Status: COMPLETED
Conditions: Critically Ill|Acute Kidney Injury
Interventions: DRUG: Citrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Loncastuximab Tesirine in Combination With Rituximab in Patients With Relapsed or Refractory Follicular Lymphoma
Status: RECRUITING
Conditions: Follicular Lymphoma
Interventions: DRUG: Loncastuximab tesirine|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: FF/UMEC/VI Inhaler: Qualitative Analysis and Subject Preference Survey
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: OTHER: Telephone interviews|OTHER: In-person focus groups|OTHER: DCE surveys- cognitive interviews|OTHER: Modified DCE|OTHER: Online DCE survey
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: HIRREM Developmental Study
Status: COMPLETED
Conditions: Sleep Initiation and Maintenance Disorders|Anxiety|Post-Traumatic Stress Disorder|Hot Flashes|Headache|Traumatic Brain Injury|Post Concussion Symptoms
Interventions: DEVICE: HIRREM
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Evaluation of Intranasal Nalmefene Using Three Dosing Regimens
Status: COMPLETED
Conditions: Opioid Overdose
Interventions: DRUG: Nalmefene Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Supportive Oncology Care at Home for Patients With Pancreatic Cancer Receiving Preoperative FOLFIRINOX
Status: COMPLETED
Conditions: Pancreas Cancer
Interventions: OTHER: Supportive Oncology Care at Home
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Multimodal Analgesia vs. Routine Care Pain Management for Lumbar Spine Fusion Surgery: A Prospective Randomized Study
Status: SUSPENDED
Conditions: Single Level Lumbar Decompression and Fusion Spine Surgery
Interventions: OTHER: Multimodal Analgesia Treatment|OTHER: Standard of Care Pain Management Protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combined Treatment for Cocaine-Alcohol Dependence - 1
Status: COMPLETED
Conditions: Alcohol Dependence|Cocaine Dependence
Interventions: DRUG: Naltrexone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PEEK Bar Versus Titanium Bar Fabricated by CAD-CAM in Mandibular Hybrid Prostheses: A Comparative Study
Status: COMPLETED
Conditions: Edentulous Jaw
Interventions: PROCEDURE: implant placement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Safety and Efficacy of Lurasidone With Different Initiation Dose in Chinese Acute Phase Patients With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Lurasidone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Milciclib in Combination With Gemcitabine in Advanced NSCLC
Status: NOT_YET_RECRUITING
Conditions: NSCLC
Interventions: DRUG: Milciclib Dose: 150 mg/day Mode of administration: oral
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Insuman Basal/Comb/Rapid in Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: insulin human (HR1799)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Genotype and Phenotype Correlation in Hereditary Thrombotic Thrombocytopenic Purpura (Upshaw-Schulman Syndrome)
Status: RECRUITING
Conditions: Thrombotic Thrombocytopenic Purpura|Congenital Thrombotic Thrombocytopenic Purpura|Familial Thrombotic Thrombocytopenic Purpura|Thrombotic Thrombocytopenic Purpura, Congenital|Upshaw-Schulman Syndrome
Interventions: OTHER: Observation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluate the Lightening Effect of the Whitening Cosmetic Product BEX-2011
Status: UNKNOWN
Conditions: Solar Lentigines
Interventions: OTHER: skin whitening cosmetic product
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Red Blood Cell Transfusion Thresholds and QOL in MDS
Status: UNKNOWN
Conditions: Myelodysplastic Syndromes (MDS)|Quality of Life|Red Blood Cell (RBC) Transfusions
Interventions: OTHER: Red Blood Cell Transfusions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Lactoferrin at Two Doses vs. Active Control on Markers of Immune Function
Status: COMPLETED
Conditions: Immune Health
Interventions: DIETARY_SUPPLEMENT: High dose Human Lactoferrin|DIETARY_SUPPLEMENT: Low dose Human Lactoferrin|DIETARY_SUPPLEMENT: Active Control Bovine Lactoferrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Free Middle Turbinate Flap for Repair of Low Flow Cerebrospinal Fluid Leak
Status: UNKNOWN
Conditions: CSF Leakage
Interventions: DEVICE: free middle turbinate flap|DEVICE: vascularized nasoseptal flap
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of the Game on Students' Intramuscular Injection Skills
Status: ACTIVE_NOT_RECRUITING
Conditions: Video Games|Students|Nursing|Infections|Intramuscular
Interventions: OTHER: Computer assisted intramuscular learning game
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Study of Rodatristat Ethyl in Patients With Pulmonary Arterial Hypertension (ELEVATE 2)
Status: COMPLETED
Conditions: Pulmonary Arterial Hypertension
Interventions: DRUG: rodatristat ethyl 300 mg tablet BID|DRUG: rodatristat ethyl 600 mg BID|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Intravitreal Bevacizumab on Clinically Significant Macular Edema
Status: UNKNOWN
Conditions: Diabetic Macular Edema
Interventions: DRUG: bevacizumab|DRUG: triamcinolone acetonide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Single-dose Study to Assess Efficacy of Canakinumab (ACZ885) in Patients With Active Juvenile Idiopathic Arthritis (SJIA)
Status: TERMINATED
Conditions: Systemic Juvenile Idiopathic Arthritis
Interventions: DRUG: Canakinumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Novel Vertical Y-shaped Tunnel Approach Versus Modified Coronally Advanced Tunnel Technique, for The Treatment of Miller Class I Gingival Recession
Status: COMPLETED
Conditions: Gingival Recession
Interventions: PROCEDURE: Y shaped Tunnel with Connective tissue graft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Soluble Fiber Dextrin on Subjective and Physiological Markers of Appetite
Status: COMPLETED
Conditions: Appetitive Behavior
Interventions: OTHER: Soluble Fiber Dextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: To Evaluate Efficacy and Long-term Safety of Ozanimod in Japanese Subjects With Moderately to Severely Active Ulcerative Colitis
Status: ACTIVE_NOT_RECRUITING
Conditions: Colitis, Ulcerative
Interventions: DRUG: Ozanimod|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Neural Signals for the Control of Assistive Devices
Status: NOT_YET_RECRUITING
Conditions: Spinal Cord Injury (SCI), Initial Encounter
Interventions: PROCEDURE: Epidural Spinal Cord Stimulation|DEVICE: Electrocorticographic|DEVICE: Electroencephalographic
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Osimertinib in Treating Participants With Stage I-IIIA EGFR-mutant Non-small Cell Lung Cancer Before Surgery
Status: ACTIVE_NOT_RECRUITING
Conditions: Stage I Non-Small Cell Lung Cancer|Stage IA Non-Small Cell Lung Cancer|Stage IB Non-Small Cell Lung Cancer|Stage II Non-Small Cell Lung Cancer|Stage IIA Non-Small Cell Lung Cancer|Stage IIB Non-Small Cell Lung Cancer|Stage IIIA Non-Small Cell Lung Cancer
Interventions: DRUG: Osimertinib|PROCEDURE: Therapeutic Conventional Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long-Acting Tacrolimus for the Treatment of Resistant Lupus Nephritis
Status: COMPLETED
Conditions: Lupus Nephritis
Interventions: DRUG: Long-acting tacrolimus (Advagraf, Astellas Pharma)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficiency of Physiotherapy Treatments for Low Back Pain in Women.
Status: COMPLETED
Conditions: Low Back Pain
Interventions: PROCEDURE: Electromagnetic Therapy|PROCEDURE: Transcutaneous Electrical Neurological Stimulation|PROCEDURE: Back School
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Fecal Microbial Transplantation in Relapsing Multiple Sclerosis Patients
Status: TERMINATED
Conditions: Autoimmune Diseases|Relapsing Multiple Sclerosis
Interventions: DRUG: Fecal microbiota
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intravitreal Sirolimus as Therapeutic Approach to Uveitis
Status: WITHDRAWN
Conditions: Uveitis|Intermediate Uveitis|Posterior Uveitis|Panuveitis
Interventions: DRUG: Intravitreal injection 440mcg|DRUG: Intravitreal injection of sirolimus 880mcg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Efficacy of Cervical Pillows in Subjects With Non-specific Chronic Neck Pain
Status: COMPLETED
Conditions: Neck Pain
Interventions: DEVICE: Viscospring PostuRite - "medium" model|OTHER: Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Effectiveness Study of Insulin Glargine (LANTUS) Initiation and Titration in Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: INSULIN GLARGINE
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: rTMS of Limbic Circuitry in Stress Modulation in Healthy Volunteers
Status: WITHDRAWN
Conditions: Stress|Healthy
Interventions: DRUG: yohimbine + hydrocortisone|DEVICE: medial prefrontal cortex rTMS|DRUG: Placebo oral tablet|DEVICE: sham rTMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study to Determine the Digestive and Physiological Effects of an Extract From Bran in Healthy Men and Women
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: wheat bran extract|OTHER: control wheat bran extract
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Early Biomarkers for ARthritic PAIN to Guide Improved Treatments for Arthritis
Status: UNKNOWN
Conditions: Osteoarthritis, Knee|Rheumatoid Arthritis|Spondyloarthritis|Psoriatic Arthritis
Interventions: PROCEDURE: Intra-articular corticosteroid injection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Randomised Phase II Open-label Study With a Phase Ib Safety lead-in Cohort of ONCOS-102, an Immune-priming GM-CSF Coding Oncolytic Adenovirus, and Pemetrexed/Cisplatin in Patients With Unresectable Malignant Pleural Mesothelioma
Status: UNKNOWN
Conditions: To Determine Safety, Tolerability and Efficacy of ONCOS-102 in Combination With Chemotherapy
Interventions: BIOLOGICAL: ONCOS-102|DRUG: Pemetrexed/cisplatin (carboplatin)|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Relapse, Efficacy and Safety of Long-term Treatment With Oracea® vs Placebo
Status: COMPLETED
Conditions: Rosacea
Interventions: DRUG: Doxycycline|DRUG: Metronidazole|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Oral Hygiene Care and Microflora in Elderly Residents
Status: COMPLETED
Conditions: Pneumonia|Aspiration
Interventions: BEHAVIORAL: Extended professional oral hygiene care|DEVICE: Electric toothbrush (Oral-B Professional Care 7000)|DEVICE: 1100 ppm sodium fluoride dentifrice (Zendium Classic)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Fecal Microbiota Transplantation for Diabetes Mellitus Type II in Obese Patients
Status: UNKNOWN
Conditions: Diabetes Mellitus, Type 2|Obesity
Interventions: PROCEDURE: gastroscopy|DRUG: Fecal Microbiota Transplantation|OTHER: high fat low fiber diet|OTHER: sham diet|OTHER: low fat high fiber diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of TAK-755 (rADAMTS13) With Little to No Plasma Exchange (PEX) Treatment in Adults With Immune-mediated Thrombotic Thrombocytopenic Purpura (iTTP)
Status: RECRUITING
Conditions: Thrombotic Thrombocytopenic Purpura (TTP)
Interventions: BIOLOGICAL: TAK-755
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing LBEC0101 to Enbrel® in Subjects With Active Rheumatoid Arthritis Despite Methotrexate Therapy
Status: UNKNOWN
Conditions: Arthritis, Rheumatoid
Interventions: DRUG: Enbrel|DRUG: LBEC0101
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dissemination of a Theory-Based Bone Health Program in Online
Status: COMPLETED
Conditions: Osteoporosis|Health Behaviors
Interventions: BEHAVIORAL: TO-BoneHealth Program (Bone Power Program)|BEHAVIORAL: TO-BoneHealth Plus Program (Bone Power Plus Program)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: ECT Pulse Amplitude and Medial Temporal Lobe Engagement
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DEVICE: MECTA Spectrum 5000Q Amplitude
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase Ib/II Study to Evaluate the Safety and Efficacy of Nivolumab in Combination With Paclitaxel in Epstein-Barr Virus(EBV)-Related, or Microsatellite Instability-High (MSI-H), or Programmed Cell Death Ligand 1 (PD-L1) Positive Advanced Gastric Cancer
Status: COMPLETED
Conditions: Recurrent/Metastatic Gastric Cancer
Interventions: DRUG: Nivolumab, Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Locally ablatiVe therApy in oLigO-pRogressive sOlid tUmorS (VALOROUS)
Status: RECRUITING
Conditions: Breast Cancer|Oligoprogressive|Head and Neck Cancer|Sarcoma|Other Cancer
Interventions: DEVICE: Ablative local therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Glimepiride on Recovery From Hypoglycemia in Participants With Type 2 Diabetes Mellitus (MK-0000-253)
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Placebo|DRUG: Glimepiride 2 mg|DRUG: Glimepiride 4 mg|PROCEDURE: Hypoglycemic Clamp
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dexamethasone-sparing Approach Including NEPA Against Emesis Caused by Cisplatin
Status: UNKNOWN
Conditions: Chemotherapy-induced Nausea and Vomiting
Interventions: DRUG: Netupitant/Palonosetron|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of Bisantrene Combined With Cytarabine or With Decitabine for Adult Subjects With Extramedullary AML and MDS
Status: WITHDRAWN
Conditions: Acute Myeloid Leukemia|Recurrent Acute Myeloid Leukemia|Refractory Acute Myeloid Leukemia|Higher Risk Myelodysplastic Syndrome|Chronic Myelomonocytic Leukemia
Interventions: DRUG: Bisantrene Dihydrochloride (high dose)|DRUG: Bisantrene Dihydrochloride (low dose)|DRUG: Cytarabine Hydrochloride|DRUG: Decitabine and cedazuridine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Curative Efficacy of Secondary Prevention for Patients With Ischemic Stroke Through Syndrome Differentiation of TCM
Status: COMPLETED
Conditions: Ischemic Stroke
Interventions: DRUG: Naoxintong Capsule|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Lenalidomide and AT-101 in Treating Patients With Relapsed B-Cell Chronic Lymphocytic Leukemia
Status: TERMINATED
Conditions: Recurrent Chronic Lymphocytic Leukemia
Interventions: DRUG: Lenalidomide|DRUG: R-(-)-Gossypol Acetic Acid|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bio-mechanical Reasoning and Lateral Specificity of Upper Cervical Joint Mobilization
Status: UNKNOWN
Conditions: Neck Pain
Interventions: OTHER: Bio-mechanically correct manual therapy at the cervical atlanto-axial joints|OTHER: Bio-mechanically in-correct manual therapy at the cervical atlanto-axial joints
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study With Aleglitazar in Patients With a Recent Acute Coronary Syndrome and Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus Type 2
Interventions: DRUG: Aleglitazar|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Double-blind, Randomized, Parallel Design Study to Compare the Effectiveness of Sugammadex Versus Neostigmine in Improving Surgical Condition in Subjects Undergoing Laryngeal Microsurgery
Status: COMPLETED
Conditions: General Anesthesia
Interventions: DRUG: Sugammadex|DRUG: Neostigmine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Psychoeducational and Behavioral Strategies in Reducing Distress and Anxiety in Patients With Multiple Myeloma and Their Family Caregivers
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: OTHER: Psychoeducational intervention|BEHAVIORAL: behavioral intervention|OTHER: counseling intervention|OTHER: educational intervention|OTHER: telephone-based intervention|OTHER: questionnaire administration|OTHER: quality-of-life assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pre-IVF Treatment With a GnRH Antagonist in Women With Endometriosis
Status: ACTIVE_NOT_RECRUITING
Conditions: Infertility|Endometriosis
Interventions: DRUG: Elagolix 200 MG|OTHER: Placebo or SOC IVF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Efficacy, Safety, and Tolerability of Brensocatib in Participants With Non-Cystic Fibrosis Bronchiectasis
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-Cystic Fibrosis Bronchiectasis
Interventions: DRUG: Brensocatib 10 mg|DRUG: Brensocatib 25 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prevention of Maternal-fetal Cytomegalovirus Transmission After Primary Maternal Infection, GW ≤ 14 (PreCyssion)
Status: ACTIVE_NOT_RECRUITING
Conditions: Congenital Cytomegalovirus Infection
Interventions: DRUG: BT097
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Tdcs And cogNitive traininG cOmbined for AUD (TANGO)
Status: RECRUITING
Conditions: Alcohol Use Disorder|Addiction
Interventions: DEVICE: TaskFlow Transcranial Electrical Stimulation device|BEHAVIORAL: Executive Function Focused Cognitive Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Epoetin Beta in Treating Anemia in Patients With Cervical Cancer
Status: COMPLETED
Conditions: Anemia|Cervical Cancer
Interventions: BIOLOGICAL: epoetin beta|DRUG: cisplatin|RADIATION: brachytherapy|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: An Exploratory Study on the Efficacy and Safety of Abatacept in the Treatment of Refractory Dermatomyositis
Status: UNKNOWN
Conditions: Dermatomyositis|Abatacept
Interventions: DRUG: Abatacept
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non-invasive VNS for PD Gait
Status: NOT_YET_RECRUITING
Conditions: Parkinson's Disease
Interventions: DEVICE: non-invasive cervical vagal nerve stimulation ncVNS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A-mode vs PalmScan Ultrasonography: Biometric Measurements.
Status: WITHDRAWN
Conditions: Axial Length (AL)|Anterior Chamber Deep (ACD)|Lens Thickness (LT)
Interventions: DEVICE: PalmScan A2000 ultrasonography system (Micro Medical Devices, Calabasas, CA)|DEVICE: Standard A-mode ultrasound (Eye Cubed™, Ellex, Adelaide, Australia).
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Preliminary Efficacy and Tolerability of NCX-1000 After Repeated Oral Doses in Patients With Elevated Portal Pressure
Status: TERMINATED
Conditions: Portal Hypertension
Interventions: DRUG: NCX-1000|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Safety and Efficacy Study of LYS-GM101 Gene Therapy in Patients With GM1 Gangliosidosis
Status: TERMINATED
Conditions: GM1 Gangliosidosis
Interventions: GENETIC: LYS-GM101
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Clinical Trial, Use of KL16-012 in Women With Fibromyalgia Refractary to Conventional Treatment.
Status: UNKNOWN
Conditions: Fibromyalgia|Cannabis
Interventions: DRUG: KL16-012|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Improving PCP Advance Care Planning for People With ADRD
Status: NOT_YET_RECRUITING
Conditions: Alzheimer Disease|Dementia|Alzheimer's Disease (Incl Subtypes)|Aging
Interventions: BEHAVIORAL: Primary Care Team Advance Care Planning With People with Alzheimer's Disease or a Related Dementia Training|BEHAVIORAL: Care as Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Exercise and Venous Compression on Upper Airway Resistance in Obese Teenagers With OSA
Status: COMPLETED
Conditions: Pediatric Obesity|Sleep Apnea, Obstructive
Interventions: OTHER: Interventional group|OTHER: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Trial of Durvalumab and Tremelimumab in Combination With SBRT in Patients With Metastatic Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Head and Neck Squamous Cell Carcinoma|Lung Cancer|Oesophageal Cancer
Interventions: DRUG: Durvalumab|DRUG: Tremelimumab|RADIATION: SBRT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT