pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Behavioural Therapy Program for Female Overactive Bladder
Status: COMPLETED
Conditions: Urinary Bladder, Overactive
Interventions: BEHAVIORAL: Structured training and leaflet|BEHAVIORAL: Structured training|BEHAVIORAL: Leaflet|BEHAVIORAL: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: JAB-21822 Combined With JAB-3312 Compared SOC in the First Line for Treatment of Advanced Non-small Cell Lung Cancer With KRAS p.G12C Mutation
Status: RECRUITING
Conditions: Advanced Non-squamous Non-small-cell Lung Cancer|Metastatic Non-squamous Non Small Cell Lung Cancer
Interventions: DRUG: JAB-21822|DRUG: Tislelizumab|DRUG: JAB-3312|DRUG: Pemetrexed|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Remote Ischemic Conditioning for Spontaneous Intracerebral Hemorrhage
Status: RECRUITING
Conditions: Intracranial Hemorrhages
Interventions: DEVICE: Remote ischemic conditioning|DEVICE: Sham remote ischemic conditioning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Early Directed Physical Therapy in the Management of Mechanically Ventilated Patients in a Medical Intensive Care Unit
Status: COMPLETED
Conditions: Mechanically Ventilated Patients
Interventions: PROCEDURE: early PT OT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of the Medtronic CoreValve® System in the Treatment of Severe, Symptomatic Aortic Stenosis in Intermediate Risk Subjects Who Need Aortic Valve Replacement (SURTAVI).
Status: ACTIVE_NOT_RECRUITING
Conditions: Severe Aortic Stenosis
Interventions: DEVICE: Medtronic CoreValve® System Transcatheter Aortic Valve Implantation (TAVI)|PROCEDURE: Surgical Aortic Valve Replacement (SAVR)|DEVICE: Medtronic CoreValve® Evolut R System Transcatheter Aortic Valve Implantation (TAVI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessing the Necessity of Prescribing Antibiotics (Clavulin or Clindamycin Versus Placebo) Post-peritonsillar Abscess Drainage
Status: WITHDRAWN
Conditions: Peritonsillar Abscess
Interventions: DRUG: Clavulin|DRUG: Randomization to Placebo|DRUG: Clindamycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Methotrexate With or Without Cyclophosphamide in Treating Patients With Lymphocytic Leukemia
Status: TERMINATED
Conditions: Leukemia
Interventions: DRUG: Cyclophosphamide|DRUG: Methotrexate|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Allogeneic Engineered Hematopoietic Stem Cell Transplant (HCT) Lacking the CD33 Protein, and Post-HCT Treatment With Mylotarg, for Patients With CD33+ AML or MDS
Status: RECRUITING
Conditions: Leukemia, Myeloid, Acute|Myelodysplastic Syndromes
Interventions: BIOLOGICAL: VOR33|DRUG: Mylotarg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Weight Loss on Intermuscular Adipose Tissue (IMAT) Signaling
Status: RECRUITING
Conditions: Obesity|Insulin Sensitivity|Muscle Weakness|Adiposity|Insulin Resistance
Interventions: BEHAVIORAL: Diet Weight Loss
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Role of Angiojet Rheolytic Thrombectomy in The Management of Iliofemoral Deep Venous Thrombosis
Status: RECRUITING
Conditions: Iliofemoral Deep Vein Thrombosis
Interventions: PROCEDURE: Angiojet Rheolytic Thrombectomy in The Management of Iliofemoral Deep Venous Thrombosis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Adagrasib in Combination With Nab-Sirolimus in Patients With Advanced Solid Tumors and Non-Small Cell Lung Cancer With a KRAS G12C Mutation (KRYSTAL -19)
Status: ACTIVE_NOT_RECRUITING
Conditions: Solid Tumor, Adult|NSCLC|Advanced Cancer|Metastatic Cancer|Malignant Neoplastic Disease
Interventions: DRUG: Adagrasib|DRUG: nab-Sirolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Supporting Secondary School Student Wellbeing Through a Mobile App and Wearable Biofeedback
Status: NOT_YET_RECRUITING
Conditions: No Disease or Condition is Being Studied|Stress Psychological|Overall Wellness
Interventions: DEVICE: Mobile app and wrist-worn monitor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Test Combination Treatments in People With Advanced Renal Cell Carcinoma
Status: COMPLETED
Conditions: Advanced Cancer
Interventions: BIOLOGICAL: Nivolumab|BIOLOGICAL: Ipilimumab|BIOLOGICAL: Relatlimab|DRUG: BMS-986205|DRUG: BMS-813160
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Open Label, Non-Comparative, Multicenter, Phase III Trial of the Efficacy, Safety and Toleration of Voriconazole in the Primary or Secondary Treatment of Invasive Fungal Infections
Status: COMPLETED
Conditions: Aspergillosis|Candidiasis|Fungemia|Mycoses
Interventions: DRUG: Voriconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Better Lithotripsy and Ureteroscopy Evaluation of Stenting (BLUES)
Status: ACTIVE_NOT_RECRUITING
Conditions: Renal Stone|Ureteral Stone
Interventions: DEVICE: Silicone (Coloplast Imajin Hydro) ureteral stent|DEVICE: Non-silicone (Polyurethane/Percuflex) ureteral stent (any manufacturer)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 3 Trial of Litx™ Plus Chemotherapy vs. Chemotherapy Only Treating Colorectal Cancer Patients With Recurrent Liver Metastases
Status: COMPLETED
Conditions: Liver Metastases|Colorectal Neoplasms|Neoplasm Metastasis|Neoplasm Recurrence, Local
Interventions: DRUG: Talaporfin sodium|PROCEDURE: Percutaneous placement of device in liver metastases|DEVICE: Interstitial light emitting diodes|DRUG: FOLFOX4 regimen|DRUG: FOLFIRI regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Discontinuation of Antithrombotic Treatment Following Patent Foramen Ovale Closure in Young Patients With Cryptogenic Stroke
Status: RECRUITING
Conditions: Patent Foramen Ovale|Ischemic Stroke|Bleeding Ulcer
Interventions: OTHER: Antiplatelet treatment discontinuation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Rosiglitazone And Fenofibrate Additive Effects on Lipids (RAFAEL)
Status: TERMINATED
Conditions: Hypertriglyceridemia in Type 4 Hyperlipidemia|Non Diabetic Subjects With Normoglycemia
Interventions: DRUG: Rosiglitazone|DRUG: Placebo (Rosiglitazone)|DRUG: Placebo (Fenofibrate)|DRUG: Fenofibrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Lumbar Erector Spinae Plane Block and Fascia Iliaca Compartment Block After Total Hip Arthroplasty
Status: RECRUITING
Conditions: Analgesia
Interventions: DRUG: Lumbar Erector spinae plane block (L-ESPB)|DRUG: Fascia iliaca compartment block (FICB)|DRUG: spinal anesthesia plane block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pembrolizumab With Androgen Deprivation Therapy and Radiotherapy for the Treatment of Patients With High Risk Localized Prostate Cancer
Status: NOT_YET_RECRUITING
Conditions: High Risk Prostate Carcinoma|Localized Prostate Adenocarcinoma|Stage I Prostate Cancer AJCC v8|Stage II Prostate Cancer AJCC v8|Stage III Prostate Cancer AJCC v8
Interventions: DRUG: Gonadotropin Releasing Hormone Agonists and Antagonists|DRUG: Bicalutamide|PROCEDURE: Biopsy|PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|PROCEDURE: Magnetic Resonance Imaging|BIOLOGICAL: Pembrolizumab|OTHER: Questionnaire Administration|RADIATION: Radiation Therapy|PROCEDURE: Bone Scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A 24-week Prospective, Open-label, Multicenter, Single-arm rPMS Study in Real-world Setting for Atectura®
Status: RECRUITING
Conditions: Asthma
Interventions: OTHER: Atectura inhalation capsule (150/80ug)|OTHER: Atectura inhalation capsule (150/160ug)|OTHER: Atectura inhalation capsule (150/320ug)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Bendamustine, Obinutuzumab, and Dexamethasone in Older Patients With Diffuse Large B-cell Lymphoma
Status: TERMINATED
Conditions: Diffuse Large B-Cell Lymphoma
Interventions: DRUG: Bendamustine Hydrochloride|BIOLOGICAL: Obinutuzumab|DRUG: Dexamethasone|OTHER: Quality-of-Life Assessment|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Repotrectinib in Pediatric and Young Adult Subjects Harboring ALK, ROS1, OR NTRK1-3 Alterations
Status: RECRUITING
Conditions: Locally Advanced Solid Tumors|Metastatic Solid Tumors|Lymphoma|Primary CNS Tumors
Interventions: DRUG: Oral repotrectinib (TPX-0005)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Erlotinib in Treating Patients With Recurrent Malignant Glioma or Recurrent or Progressive Meningioma
Status: COMPLETED
Conditions: Adult Anaplastic Astrocytoma|Adult Anaplastic Oligodendroglioma|Adult Giant Cell Glioblastoma|Adult Glioblastoma|Adult Gliosarcoma|Adult Grade I Meningioma|Adult Grade II Meningioma|Adult Grade III Meningioma|Recurrent Adult Brain Tumor
Interventions: DRUG: erlotinib hydrochloride|OTHER: laboratory biomarker analysis|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination of Predictive Biomarkers to Increase Diagnostics Efficiency of Autism Spectrum Disorder
Status: RECRUITING
Conditions: Autism Spectrum Disorder
Interventions: DIAGNOSTIC_TEST: Salivary collection|DIAGNOSTIC_TEST: eye-tracking recorder|DIAGNOSTIC_TEST: neuropsychological assessment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Sleep Disruption in New Mothers: An Intervention Trial
Status: COMPLETED
Conditions: Pregnancy|Postpartum Period|Sleep Disturbance
Interventions: BEHAVIORAL: Sleep hygiene|BEHAVIORAL: Dietary information|DRUG: Acetaminophen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effects of Acupuncture in Overcoming Inflammatory Response to COVID-19 Mild-moderate Symptoms
Status: COMPLETED
Conditions: Acupuncture|Covid19
Interventions: COMBINATION_PRODUCT: acupuncture and standard care|DRUG: standard care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Long-term Study of The Press Fit Condylar (P.F.C.) Sigma Total Knee Replacement System
Status: TERMINATED
Conditions: Knee Osteoarthritis
Interventions: DEVICE: P.F.C. Sigma Total Knee System
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Casting Versus Percutaneus Pinning Treatment of Pediatric Overriding Distal Forearm Fractures
Status: RECRUITING
Conditions: Pediatric Overriding Distal Metaphyseal Radius Fractures
Interventions: PROCEDURE: Cast immobilization|PROCEDURE: Percutaneus pinning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Relative Bioavailability Study of Bupropion Extended-Released 150 mg Tablets Under Fasting Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Abrika Bupropion 150 mg Extended-Released Tablet|DRUG: Wellbutrin SR® 150 mg Extended-Release Tablet, single dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Acute Cognitive Changes During Atrial Fibrillation Episodes (AFCOG)
Status: RECRUITING
Conditions: Atrial Fibrillation|Cognitive Symptom|Executive Dysfunction|Cognitive Change|Cognitive Impairment|Cognitive Impairment, Mild
Interventions: OTHER: Standard of Care Interventions to convert patient from atrial fibrillation to normal rhythm
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety of MP-424, Peginterferon Alfa-2b, and Ribavirin in Patients With Chronic Hepatitis C Who Relapsed After Previous Interferon Based Therapy
Status: COMPLETED
Conditions: Chronic Hepatitis C
Interventions: DRUG: MP-424|DRUG: Ribavirin|DRUG: Peginterferon Alfa-2b
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dapsone Gel 5% and Tazarotene Cream 0.1% Versus Tazarotene Cream 0.1% Monotherapy for Facial Acne Vulgaris
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: Dapsone|DRUG: Tazarotene
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Single-Blind Study Assessing the Use of a Topical Antioxidant With A Series of Laser Procedures to Reduce Sebum Production
Status: RECRUITING
Conditions: Acne
Interventions: DRUG: Topical Antioxidant Serum|DEVICE: AviClear Laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare Oxycodone/Naloxone Prolonged Release Against Codeine/Paracetamol in the Treatment of Moderate to Severe Chronic Low Back Pain or Pain Due to Osteoarthritis
Status: COMPLETED
Conditions: Osteoarthritis|Back Pain
Interventions: DRUG: Oxycodone/Naloxone|DRUG: Codeine/Paracetamol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics of Melatonin Administered in Oral, Lotion, and Bubble Bath Formulations
Status: NOT_YET_RECRUITING
Conditions: Sleep
Interventions: DIETARY_SUPPLEMENT: Melatonin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: EFFECTS OF INSPIRATORY MUSCLE TRAINING IN POST-COVID-19 PATIENTS
Status: COMPLETED
Conditions: Covid19
Interventions: OTHER: TREATMENT GROUP (TG)|OTHER: CONTROL GROUP (CG)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: EMD 525797 in Colorectal and Ovarian Cancer Patients With Liver Metastases
Status: COMPLETED
Conditions: Colorectal and Ovarian Cancer Patients With Liver Metastases
Interventions: BIOLOGICAL: EMD 525797
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mepolizumab Effectiveness in Patients With Chronic Rhinosinusitis, Nasal Polyps and Comorbid Severe Eosinophilic Asthma
Status: RECRUITING
Conditions: Chronic Rhinosinusitis With Nasal Polyps|Severe Eosinophilic Asthma|Chronic Rhinosinusitis Without Nasal Polyps
Interventions: DRUG: Mepolizumab 100 MG
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Dexmedetomidine Sedation on Delirium and Haemodynamic in Mechanical Ventilated Elderly Patients
Status: UNKNOWN
Conditions: Safety of Dexmedetomidine Sedation
Interventions: DRUG: Dexmedetomidine|DRUG: Midazolam|DRUG: Fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Growth Factors Release of PRF and PRGF
Status: COMPLETED
Conditions: Periodontitis
Interventions: PROCEDURE: group 1 bio-oss bone xenograft|PROCEDURE: group 2 platelet rich in growth factor (autogenous platelet rich in growth factor)|PROCEDURE: group 3 platelet rich fibrin (autogenous platelet rich fibrin)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Determine the Bioequivalence of Two Products Containing Rosuvastatin (20 mg/Tablet)
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Rosuvastatin 20 mg film-coated tablets|DRUG: Crestor 20 mg film-coated tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Inetetamab Combined With Anti-PD-1 Monoclonal Antibody and Albumin-Bound Paclitaxel for HER2+ Metastatic Breast Cancer
Status: NOT_YET_RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Inetetamab|DRUG: Toripalimab|DRUG: Albumin-Bound Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of MMF in Treatment of IIM-ILD and Its Effect on Peripheral Blood Treg Cells
Status: UNKNOWN
Conditions: Idiopathic Inflammatory Myopathy|Interstitial Lung Disease
Interventions: DRUG: Mycophenolate Mofetil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Safety and Antiviral Activity of Doses of JNJ-53718678 in Children (>=28 Days to <=3 Years) With Respiratory Syncytial Virus Infection
Status: TERMINATED
Conditions: Respiratory Syncytial Virus Infections
Interventions: DRUG: JNJ-53718678|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of Nebulized TD-4208 for Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: DRUG: TD-4208|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A First-in-human Study of Multiple Doses of BB-1701 in Subjects With Locally Advanced/Metastatic HER2 Expressing Solid Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Locally Advanced/Metastatic HER2 Positive Solid Tumors
Interventions: DRUG: BB-1701
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assess the Efficacy/Safety of Intravitreal Ranibizumab in Patients With Vision Loss Due to Choroidal Neovascularization.
Status: COMPLETED
Conditions: Choroidal Neovascularization (CNV)
Interventions: DRUG: Ranibizumab|OTHER: Sham control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Simultaneous Traction and Neural Mobilization
Status: COMPLETED
Conditions: Cervical Radiculopathy
Interventions: OTHER: Simultaneous Cervical Traction & Neural Mobilization|OTHER: consecutive Cervical Traction & Neural Mobilization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of N-acetylcysteine on Low T3 Syndrome
Status: COMPLETED
Conditions: Acute Myocardial Infarction|Euthyroid Sick Syndrome|Ischemic Heart Disease
Interventions: DRUG: N-acetylcysteine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Inpatient Versus Outpatient Cervical Ripening
Status: TERMINATED
Conditions: Pregnancy Related|Labor|Induction|Cervical Ripening
Interventions: OTHER: Inpatient Foley catheter|OTHER: Outpatient Foley catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Study Evaluating Safety/Efficacy of OTX-DP for Treatment of Ocular Inflammation and Pain After Cataract Surgery
Status: COMPLETED
Conditions: Ocular Inflammation and Pain
Interventions: DRUG: OTX-DP (Dexamethasone punctum plug)|DRUG: Placebo Vehicle Punctum Plug
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Radiation Oncology-Biology Integration Network (ROBIN) Molecular Characterization Trial (MCT) of Standard Short Course Radiotherapy for Rectal Cancer
Status: RECRUITING
Conditions: Rectal Cancer
Interventions: RADIATION: Short Course Radiation Therapy (scRT)|PROCEDURE: Total Mesenteric Excision (TME)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study Evaluating the Safety, Tolerability and Activity of One Dose of PAZ-417 Given to Healthy Japanese Subjects
Status: COMPLETED
Conditions: Alzheimer Disease|Healthy
Interventions: DRUG: PAZ-417|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess Adverse Events and Change in Disease Activity of Intravenous (IV) Lemzoparlimab With or Without Oral/IV Dexamethasone and in Combination With Oral/IV/Subcutaneous Anti-Myeloma Regimens in Adult Participants With Multiple Myeloma
Status: TERMINATED
Conditions: Multiple Myeloma
Interventions: BIOLOGICAL: Lemzoparlimab|DRUG: Dexamethasone|DRUG: Carfilzomib|DRUG: Pomalidomide|BIOLOGICAL: Daratumumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of NPO-11 in Patients Undergoing Gastrointestinal Endoscopy
Status: COMPLETED
Conditions: Patients Undergoing Gastrointestinal Endoscopy
Interventions: DRUG: NPO-11|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Omega 3 Supplementation in Cystic Fibrosis Patients
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DIETARY_SUPPLEMENT: omega-3 triglycerides|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: High Volume Plasma Exchange in Children With Acute Liver Failure and Acute on Chronic Liver Failure
Status: COMPLETED
Conditions: Acute Liver Failure
Interventions: BIOLOGICAL: High Volume Plasma Exchange|DRUG: Hypertonic 3% saline|DRUG: Mannitol|DEVICE: Elective positive pressure ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Coronary Artery Plaque Burden and Morphology in Type 2 Diabetes Mellitus.
Status: UNKNOWN
Conditions: Type2 Diabetes|Atherosclerosis|Plaque, Atherosclerotic|Plaque Vulnerability|Diabetes Complications|Microalbuminuria|Coronary Computed Tomography Angiography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical Trial of Adjuvant Chemotherapy Followed by Concurrent Chemoradiotherapy Compared With Adjuvant Chemotherapy Alone in Patients With Gallbladder Carcinoma and Extrahepatic Cholangiocarcinoma
Status: UNKNOWN
Conditions: Malignant Neoplasm Other Gallbladder/Extrahepatic Bile Duct
Interventions: RADIATION: Concurrent Chemoradiotherapy|DRUG: capecitabine|DRUG: gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Synthetic Bone Graft for Treatment of Peri-implantitis
Status: TERMINATED
Conditions: Peri-Implantitis
Interventions: DEVICE: easy-graft CLASSIC (beta-Tricalcium Phosphate)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Preemptive Epidural Ropivacaine for Postoperative Pain Relief in Degenerative Lumbar Spine Surgery
Status: UNKNOWN
Conditions: Postoperative Pain
Interventions: DRUG: Placebo (one of medication)|DRUG: Ropivacaine (epidural injection)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Anti Helicobacter Pylori Efficacy Assessment of Unani Formulation and Quintuple Regimen
Status: COMPLETED
Conditions: H.Pylori Infection
Interventions: DRUG: Pylorin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Glycemic Changes During Exercise in Children With Type 1 Diabetes
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: OTHER: Algorithmic changes in insulin therapy.|OTHER: Treadmill exercises|DRUG: Insulin aspart, glargine and detemir
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: New Markers of Glycation to Predict Gestational Diabetes Mellitus and Macrosomia.
Status: RECRUITING
Conditions: Macrosomia, Fetal|Gestational Diabetes Mellitus in Pregnancy
Interventions: DIAGNOSTIC_TEST: Pregnant women
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Weight Loss With Intensive Lifestyle Modifications Plus Bariatric Surgery Versus Liraglutide 3 mg
Status: COMPLETED
Conditions: Obesity
Interventions: DRUG: LIRAGLUTIDE 3 Mg/0.5 mL (18 Mg/3 mL) SUB-Q PEN INJECTOR (ML)|OTHER: lifestyle modification|OTHER: sleeve gastrectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Trial of Two Analgesics in Elderly ED Patients
Status: WITHDRAWN
Conditions: Pain
Interventions: DRUG: Oxycodone/acetaminophen|DRUG: Ibuprofen/acetaminophen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Thoracic Epidural Analgesia or Four-Quadrant Transversus Abdominus Plane Block in Reducing Pain in Patients Undergoing Liver Surgery
Status: RECRUITING
Conditions: Liver and Intrahepatic Bile Duct Disorder
Interventions: DRUG: Bupivacaine|DRUG: Fentanyl|DRUG: Hydromorphone Hydrochloride|DEVICE: Implanted Medical Device|DEVICE: Implanted Medical Device|DRUG: Liposomal Bupivacaine|BEHAVIORAL: Questionnaire
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Biological Prospective Study in Patients With Metastatic Pancreatic NETs Treated With Everolimus
Status: COMPLETED
Conditions: Pancreatic Neuroendocrine Tumour Metastatic
Interventions: DRUG: Everolimus 10 mg daily
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: An Evaluation of Virtual Student Health Center Among Incarcerated Juvenile Offenders
Status: COMPLETED
Conditions: Lack of Knowledge About Condoms and Birth Control|Adolescent Sexual Intercourse|Sexual Intercourse Without a Condom or Birth Control|Unplanned Pregnancies
Interventions: OTHER: "Healthy U" tablet application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy Evaluation and Influencing Factors of Argon Laser Peripheral Iridoplasty in Acute Angle Closure Glaucoma
Status: UNKNOWN
Conditions: Acute Angle-Closure Glaucoma
Interventions: DEVICE: Argon laser peripheral iridoplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Application of Left Colic Artery Preservation, Anastomotic Reinforcing Sutures and Transanal Tube in Robotic Low Anterior Resection
Status: UNKNOWN
Conditions: Rectal Cancer
Interventions: DEVICE: Transanal tube placement|PROCEDURE: Left colic artery preservation|PROCEDURE: Anastomotic reinforcing sutures|DEVICE: Robotic surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radiolabeled Monoclonal Antibody in Treating Patients With Advanced Ovarian Epithelial Cancer
Status: COMPLETED
Conditions: Ovarian Cancer
Interventions: BIOLOGICAL: 90Y-hu3S193|BIOLOGICAL: 111In-hu3S193
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Performance of An Alkasite Based Restorative Material With And Without Adhesive
Status: COMPLETED
Conditions: Dental Restoration Failure
Interventions: OTHER: Cention N|OTHER: Cention N + Adhesive|OTHER: Bulk Fill Composite
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Crural Repair During Laparoscopic Sleeve Gastrectomy in Patients With a Lax Gastroesophageal Junction
Status: RECRUITING
Conditions: Obesity|Bariatric Surgery Candidate|Esophagus Injury|Gastroesophageal Reflux
Interventions: PROCEDURE: Laparoscopic sleeve gastrectomy with concomitant hiatal hernia repair arm|PROCEDURE: Laparoscopic sleeve gastrectomy arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy Evaluation of SYSTANE® ULTRA in Patients Scheduled for Cataract Surgery
Status: COMPLETED
Conditions: Dry Eye|Cataract Surgery
Interventions: OTHER: FID 112903 (SYSTANE® ULTRA Lubricant Eye Drops) plus standard of care|OTHER: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Alemtuzumab or Tocilizumab in Combination With Etoposide and Dexamethasone for the Treatment of Adult Patients With Hemophagocytic Lymphohistiocytosis
Status: COMPLETED
Conditions: Leukemia
Interventions: DRUG: Alemtuzumab|DRUG: Etoposide|DRUG: Dexamethasone|DRUG: Methotrexate|BEHAVIORAL: Phone Call|DRUG: Tocilizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HRS9531 Injection in Obese Subjects With Heart Failure With Preserved Ejection Fraction
Status: RECRUITING
Conditions: Heart Failure With Preserved Ejection Fraction
Interventions: DRUG: HRS9531|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Oral Upadacitinib (RINVOQ) Tablets to Assess Adverse Events and Change in Disease Symptoms in Korean Participants With Moderate to Severe Active Rheumatoid Arthritis, Atopic Dermatitis, Ankylosing Spondylitis or Psoriatic Arthritis
Status: RECRUITING
Conditions: Rheumatoid Arthritis (RA)|Atopic Dermatitis (AD)|Ankylosing Spondylitis (AS)|Psoriatic Arthritis (PsA)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study on the Effectiveness of Multidomain Intervention Program for Reducing Risks of Dementia
Status: COMPLETED
Conditions: Alzheimer Disease
Interventions: BEHAVIORAL: Active control|BEHAVIORAL: Intensive + Maintenance program|BEHAVIORAL: Intensive program only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: COVID-19 Disease and Coagulopathy: Assessment of Clotting Factor Levels in Patients With SARS-CoV-2 Infection
Status: COMPLETED
Conditions: SARS-COV2 Infection|COVID-19 Disease|Hospitalized Patients
Interventions: DRUG: low molecular weight Heparin as standard of care treatment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: An Extension Study of V203-AD Study to Evaluate the Safety, Tolerability, Immunogenicity, and Efficacy of UB-311
Status: TERMINATED
Conditions: Alzheimer's Disease
Interventions: BIOLOGICAL: UB-311|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I, Open-Labeled, Single-Arm, Dose Escalation, Clinical and Pharmacology Study of Dichloroacetate (DCA) in Patients With Recurrent and/or Metastatic Solid Tumours
Status: COMPLETED
Conditions: Neoplasms
Interventions: DRUG: Dichloroacetate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Anti-rejection Drug, Tacrolimus, in African-Americans With Kidney Transplant
Status: WITHDRAWN
Conditions: Kidney Disease, End-Stage|Donor Specific Antibodies|Acute Rejection of Renal Transplant
Interventions: DRUG: Envarsus XR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Dietary Protein Restriction on Prognosis in Patients With Diabetic Nephropathy
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus With Diabetic Nephropathy
Interventions: DIETARY_SUPPLEMENT: low protein diet|DIETARY_SUPPLEMENT: normal protein diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Topical GW842470X In Adults Patients With Moderate Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis|Dermatitis, Atopic
Interventions: DRUG: GW842470X cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Study of a Mean Pulmonary Artery Pressure-Targeted Approach With Early and Rapid Treprostinil Therapy to Reverse Right Ventricular Remodeling in Participants With Pulmonary Arterial Hypertension
Status: RECRUITING
Conditions: Pulmonary Arterial Hypertension
Interventions: DRUG: Parenteral Treprostinil|DRUG: Oral Treprostinil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Pharmacodynamic Study of Panzem® NCD in Patients With Hormone-Refractory Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: Panzem® NCD
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of MiSight ® Contact Lenses in Reducing the Progression of Childhood Myopia.
Status: COMPLETED
Conditions: Myopia
Interventions: DEVICE: omafilcon A|DEVICE: Spectacle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 27-gauge Vitrectomy Wound Integrity: a Prospective, Randomized Trial Comparing Angled Versus Straight Entry
Status: COMPLETED
Conditions: Epiretinal Membrane
Interventions: DEVICE: 27-gauge vitrectomy wound construction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Neurotoxicity Characterization Study of Nab-paclitaxel Versus Conventional Paclitaxel in Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Paclitaxel 80 mg/m2|DRUG: Nab-paclitaxel 100 mg/m2 days 1, 8 and 15|DRUG: Nab-paclitaxel 150 mg/m2 days 1, 8 and 15|DRUG: Nab-paclitaxel 150 mg/m2 days 1 and 15
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Value of Amniopatch in Preterm Premature Rupture of Membranes
Status: COMPLETED
Conditions: Preterm Premature Rupture of Membrane
Interventions: DRUG: Antibiotics|DRUG: Corticosteroid|PROCEDURE: Amniopatch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Observation of Pulsed Dye Laser and Intense Pulsed Light in Treating Facial Telangiectasia
Status: COMPLETED
Conditions: Telangiectasia
Interventions: DEVICE: Pulsed dye laser
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: EffectiVenEss of a Rehabilitation Treatment With Nordic Walking in obEse or oveRweight Patients
Status: RECRUITING
Conditions: Cardiovascular Diseases|Diabete Type 2|Overweight and Obesity
Interventions: OTHER: Nordic Walking (NW)|OTHER: Standard Rehabilitation (SR)|OTHER: Cardiological Counselling (CC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Effect of Coenzyme Q10 on Endothelial, Vascular and Myocardial Function
Status: RECRUITING
Conditions: Non-Alcoholic Fatty Liver Disease
Interventions: DRUG: Q10
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Short-term Endothelin A Receptor Blockade in Patients With On-pump CABG
Status: UNKNOWN
Conditions: Coronary Artery Disease|Aorto-coronary Bypass Grafting
Interventions: DRUG: BQ-123|DRUG: NaCl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Switching Study of Kidney Transplant Patients With Tremor to LCP-Tacro (STRATO)
Status: COMPLETED
Conditions: Renal Failure|Tremors
Interventions: DRUG: Prograf|DRUG: LCP-Tacro
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Herbal Preparation Used as Adjuvant Therapy on Diabetic Ulcers
Status: COMPLETED
Conditions: Diabetic Foot Ulcer|Amputation
Interventions: DRUG: TCM|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Vulnerability to Carotid Stenosis by MultiModal Imaging and Cellular and Molecular Biology Analysis
Status: TERMINATED
Conditions: Internal Carotid Artery|Atheromatous Stenosis
Interventions: OTHER: Data collection|PROCEDURE: collection of the carotid plaque (surgical specimen)|OTHER: anatomopathological, histological, cellular and molecular biology examinations (metabolomics and transcriptomics) on surgical specimens
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Treatment and Control of Atopic Dermatitis With 0.1% Tacrolimus Ointment
Status: COMPLETED
Conditions: Dermatitis, Atopic
Interventions: DRUG: tacrolimus ointment|DRUG: Placebo ointment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nasal High Flow at Acute Hart Failure
Status: TERMINATED
Conditions: Decompensated Heartfailure|Cardio-renal Syndrom
Interventions: DEVICE: Nasal high flow|DEVICE: Conventional nasal oxygen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics, Safety and Tolerability Study of Single Dose of Abatacept 125mg Administered Subcutaneously
Status: UNKNOWN
Conditions: Rheumatoid Arthritis (RA)
Interventions: DRUG: Abatacept|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Blueberries in Older Adults
Status: COMPLETED
Conditions: Blood Pressure|Orthostatic Hypotension|Vascular Diseases
Interventions: BEHAVIORAL: Blueberry Consumption|BEHAVIORAL: Dried Date Consumption
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effectiveness of Transcranial Magnetic Stimulation (TMS) in Smoking Cessation, Combining Withdrawal Stimulation Followed by Maintenance Stimulation to Prevent Relapse
Status: RECRUITING
Conditions: Smoking Cessation
Interventions: OTHER: Transcranial Magnetic Stimulation sessions|OTHER: Evaluations
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Tramadol as a Treatment for Opioid Addiction
Status: COMPLETED
Conditions: Opioid-Related Disorders
Interventions: DRUG: Tramadol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Preemptive Pudendal Nerve Block Using Bupivacaine Versus Ropivacaine on Post-operative Pain After Posterior Vaginal Repair.
Status: UNKNOWN
Conditions: Post-operative Pain After Posterior Vaginal Repair
Interventions: DEVICE: Pudendal Nerve Block needle in pre-packaged kits that include both the trumpet and the needle. The needle will limits its depth of penetration to 5 mm beyond the trumpet.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Tradipitant for Functional Dyspepsia
Status: ENROLLING_BY_INVITATION
Conditions: Functional Dyspepsia
Interventions: DRUG: Tradipitant|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Zometa Adjuvant Treatment of Malignant Pleural Effusion Due To Non-Small Cell Lung Cancer
Status: TERMINATED
Conditions: Malignant Pleural Effusion|Non Small Cell Lung Cancer
Interventions: DRUG: zoledronic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Mindfulness and Yoga in Basic Combat Training
Status: COMPLETED
Conditions: Depressive Symptoms|Anxiety|Sleep|Emotion Regulation|Pain|Military Operations|Cohesion, Social|Mindfulness|Yoga|Leadership|Health, Subjective|Stress|Mood|Musculoskeletal Injury
Interventions: BEHAVIORAL: Mindfulness Based Attention Training (MBAT) and Yoga
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Long-term Antibody Persistence of GSK Biologicals' Meningococcal Vaccine GSK134612 in Healthy Adolescents/Adults
Status: COMPLETED
Conditions: Infections, Meningococcal
Interventions: BIOLOGICAL: Nimenrix|PROCEDURE: Blood sampling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Multiple Ascending Dose Study of TRN-157 in Stable Mild and Moderate Asthmatics
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: TRN-157|OTHER: Placebo|DRUG: Tiotropium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bacterial Decolonization to Prevent Radiation-induced Oral Mucositis
Status: RECRUITING
Conditions: Nasopharyngeal Carcinoma|Radiation-induced Oral Mucositis|Bacterial Colonization|Quality of Life
Interventions: DRUG: Mupirocin Ointment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Sorafenib Tosylate in Treating Younger Patients With Relapsed or Refractory Rhabdomyosarcoma, Wilms Tumor, Liver Cancer, or Thyroid Cancer
Status: COMPLETED
Conditions: Childhood Hepatocellular Carcinoma|Papillary Thyroid Cancer|Previously Treated Childhood Rhabdomyosarcoma|Recurrent Childhood Liver Cancer|Recurrent Childhood Rhabdomyosarcoma|Recurrent Thyroid Cancer|Recurrent Wilms Tumor and Other Childhood Kidney Tumors
Interventions: DRUG: sorafenib tosylate|OTHER: pharmacological study|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Antihyperalgesic Effect of Tapentadol in Two Human Experimental Models
Status: TERMINATED
Conditions: Pain|Hyperalgesia|Allodynia
Interventions: DRUG: Tapentadol immediate release|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II Trial of First-line Doxycycline for Ocular Adnexal Marginal Zone Lymphoma Treatment
Status: ACTIVE_NOT_RECRUITING
Conditions: Marginal Zone Lymphoma of Ocular Adnexal
Interventions: DRUG: Doxycycline
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT