pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Feasibility, Acceptability and Effect of a Transdiagnostic Psychological Treatment for Anxiety and Depression in Youth.
Status: RECRUITING
Conditions: Anxiety Depression|CBT
Interventions: BEHAVIORAL: Unified Protocol (UP-C/A) for children and youth with anxiety disorders and /or depression
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Effectiveness of Progestin-Primed Versus GnRH Antagonist Protocols in Vietnamese Women Undergoing In-vitro Fertilization
Status: RECRUITING
Conditions: IVF
Interventions: PROCEDURE: Controlled Ovarian Stimulation Protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Liver Regional Oxygen Saturation in Preterm Patent Ductus Arteriosus
Status: RECRUITING
Conditions: Patent Ductus Arteriosus|Circulation|Newborn Morbidity|Premature Birth
Interventions: DEVICE: near-infrared spectroscopy based cerebral/somatic oximeter system (INVOS™ system manufactured by Medtronics)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Disulfiram/Copper With Concurrent Radiation Therapy and Temozolomide in Patients With Newly Diagnosed Glioblastoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Glioblastoma Multiforme
Interventions: DRUG: Disulfiram|DRUG: Copper Gluconate|PROCEDURE: Surgery|RADIATION: Radiation|DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Capsinoids on Brown Adipose Tissue Activation in Obesity
Status: COMPLETED
Conditions: Weight Loss
Interventions: DIETARY_SUPPLEMENT: Capsinoid|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Opioid Based Anaesthesia vs Opioid Free Anesthesia in Cleft Lip, Palate ,Alveolus Surgery.
Status: UNKNOWN
Conditions: Intravenous Anesthesia
Interventions: DRUG: Fentanyl，Remifentanil|DRUG: Ketamine,Dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: An Investigational Immuno-therapy Study of Nivolumab, Compared to Placebo, in Patients With Bladder or Upper Urinary Tract Cancer, Following Surgery to Remove the Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Various Advanced Cancer
Interventions: BIOLOGICAL: Nivolumab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Bosentan on Endothelial Function in Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Bosentan|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Two Doses of Intranasal Dexmedetomidine for Premedication in Children
Status: UNKNOWN
Conditions: Anxiety, Separation
Interventions: DRUG: Dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Learn How Different Amounts of the Study Medicine Called PF-07976016 Are Tolerated and Act in The Body in Healthy Adults
Status: ACTIVE_NOT_RECRUITING
Conditions: Healthy
Interventions: DRUG: PF-07976016|DRUG: Placebo|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Persistent Inflammation, Immunosuppression and Catabolism Syndrome (PICS): A New Horizon for Surgical Critical Care and Induced Frailty
Status: ACTIVE_NOT_RECRUITING
Conditions: Sepsis
Interventions: OTHER: Frailty Measurements|OTHER: Modified Minnesota Leisure Time Activities|OTHER: Computed tomography morphometrics|OTHER: Mobility Monitors
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase II Study of Neo-Adjuvant Gemcitabine, Cisplatin and Bevacizumab in Stage IIIA (N2) Non-Squamous Cell Non-Small Cell Lung Cancer
Status: TERMINATED
Conditions: NSCLC|Stage IIIA (N2)
Interventions: DRUG: Gemcitabine|DRUG: Cisplatin|DRUG: Bevacizumab|PROCEDURE: Surgery|DRUG: Etoposide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cadonilimab With Chemotherapy in Treating Advanced Biliary Cancer
Status: RECRUITING
Conditions: Cholangiocarcinoma Non-resectable
Interventions: DRUG: Candonilimab|DRUG: Cisplatin|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Vestibular Rehabilitation in Patients With Bilateral Vestibular Hypofunction
Status: COMPLETED
Conditions: Individuals With Vestibular Hypofunction|Individuals Between the Ages of 18-65
Interventions: OTHER: vestibular rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gastrointestinal Ulceration in Patients on Dual Antiplatelet Therapy After Percutaneous Coronary Intervention
Status: COMPLETED
Conditions: Acute Coronary Syndrome
Interventions: PROCEDURE: Video Capsule Endoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mistletoe Therapy in Primary and Recurrent Inoperable Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DRUG: Mistletoe extract (Iscador Qu)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Study Assessing Secured Access to Vemurafenib for Patients With Tumors Harboring BRAF Genomic Alterations
Status: ACTIVE_NOT_RECRUITING
Conditions: Solid Tumors|Hematologic Cancers|Metastatic Cancers
Interventions: DRUG: Vemurafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Computed Tomography Coronary Angiography in Patients With a Previous Coronary Artery Bypass Graft Surgery Trial
Status: COMPLETED
Conditions: Coronary Artery Bypass Surgery
Interventions: PROCEDURE: Coronary angiography +/- percutaneous coronary intervention|PROCEDURE: CT-Coronary Angiography + Coronary angiography +/- percutaneous coronary intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Role of Corticosteroids and Vestibular Exercises in Recovery of Vestibular Neuritis
Status: UNKNOWN
Conditions: Vestibular Neuritis
Interventions: DRUG: Corticosteroids|OTHER: Vestibular exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prevention of Low Back Pain in the Military
Status: COMPLETED
Conditions: Low Back Pain
Interventions: BEHAVIORAL: Traditional Army training|BEHAVIORAL: Core stabilization exercise only|BEHAVIORAL: Psychosocial education class only|BEHAVIORAL: Core stabilization and psychosocial education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Open-label Extension Study of AbobotulinumtoxinA (Dysport®) for the Treatment of Cervical Dystonia
Status: COMPLETED
Conditions: Cervical Dystonia
Interventions: BIOLOGICAL: Botulinum toxin type A
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Aspirin on Patency of Metal Stent in Malignant Distal Bile Duct Obstruction
Status: TERMINATED
Conditions: Biliary Stasis, Extrahepatic
Interventions: DRUG: Aspirin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Managing Medication-induced Constipation in Cancer: A Clinical Trial
Status: COMPLETED
Conditions: Constipation
Interventions: OTHER: Laxative Treatment|OTHER: Standard of Care|OTHER: Assessment Questionnaires
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Low-Fat Compared to Low-Carbohydrate Diet in Subjects With Multifactorial Chylomicronemia
Status: COMPLETED
Conditions: Multifactorial Chylomicronemia (MCM)
Interventions: OTHER: Dietary intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Clinical Trial of Gemcitabine and Doxil® for Metastatic Renal Cell Carcinoma
Status: COMPLETED
Conditions: Metastatic Renal Cell Carcinoma
Interventions: DRUG: Gemcitabine|DRUG: Doxil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Perioperative Palliative Care Surrounding Cancer Surgery for Patients & Their Family Members
Status: COMPLETED
Conditions: Gastrointestinal Cancer
Interventions: OTHER: Surgeon-palliative care team co management|OTHER: Surgeon team alone management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Topical (Intra-Articular) Tranexamic Acid and Transfusion Rates Following Hip Hemiarthroplasty
Status: COMPLETED
Conditions: Femoral Neck Fractures
Interventions: DRUG: Tranexamic Acid|DRUG: Placebo (saline)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ipilimumab With or Without Dabrafenib, Trametinib, and/or Nivolumab in Treating Patients With Melanoma That Is Metastatic or Cannot Be Removed by Surgery
Status: TERMINATED
Conditions: BRAF V600E Mutation Present|BRAF V600K Mutation Present|Metastatic Melanoma|Stage III Cutaneous Melanoma AJCC v7|Stage IIIA Cutaneous Melanoma AJCC v7|Stage IIIB Cutaneous Melanoma AJCC v7|Stage IIIC Cutaneous Melanoma AJCC v7|Stage IV Cutaneous Melanoma AJCC v6 and v7
Interventions: DRUG: Dabrafenib|BIOLOGICAL: Ipilimumab|OTHER: Laboratory Biomarker Analysis|BIOLOGICAL: Nivolumab|DRUG: Trametinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Pharmacokinetics and Pharmacodynamics of BIBR 1048 MS Capsule in Healthy Male Subjects of Japanese and Caucasian Origin
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BIBR 1048 MS low dose|DRUG: BIBR 1048 MS medium dose|DRUG: BIBR 1048 MS high dose
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of App-driven Deep Breathing (NEURODIGITX) on Anxiety Levels and Quality of Life in Caregivers
Status: NOT_YET_RECRUITING
Conditions: Anxiety Disorders|Hospital Workers|Deep Breath
Interventions: OTHER: NeurodigitX|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Directly Observed Therapy for HCV in Chennai, India
Status: COMPLETED
Conditions: Hepatitis C, Chronic
Interventions: DRUG: Sofosbuvir|DRUG: Pegylated Interferon alfa-2a|DRUG: Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Safety and Efficacy of HK-660S in Patients With Primary Sclerosing Cholangitis
Status: COMPLETED
Conditions: Primary Sclerosing Cholangitis
Interventions: DRUG: HK-660S|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nivolumab for Relapsed, Refractory, or Detectable Disease Post Chimeric Antigen Receptor T-cell Treatment in Patients With Hematologic Malignancies
Status: ACTIVE_NOT_RECRUITING
Conditions: Recurrent Chronic Lymphocytic Leukemia|Recurrent Diffuse Large B-Cell Lymphoma|Recurrent Follicular Lymphoma|Recurrent Grade 1 Follicular Lymphoma|Recurrent Grade 2 Follicular Lymphoma|Recurrent Grade 3 Follicular Lymphoma|Recurrent Grade 3a Follicular Lymphoma|Recurrent Marginal Zone Lymphoma|Recurrent Non-Hodgkin Lymphoma|Recurrent Plasma Cell Myeloma|Refractory Chronic Lymphocytic Leukemia|Refractory Diffuse Large B-Cell Lymphoma|Refractory Follicular Lymphoma|Refractory Marginal Zone Lymphoma|Refractory Non-Hodgkin Lymphoma|Refractory Plasma Cell Myeloma|Recurrent Mantle Cell Lymphoma|Refractory Mantle Cell Lymphoma
Interventions: BIOLOGICAL: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intranasal vs Buccal vs Intramuscular Midazolam for the Home and Emergency Treatment of Acute Seizures
Status: COMPLETED
Conditions: Convulsions
Interventions: DRUG: administration of Nasal midazolam in home group as a rescue medication for seizure control.|DRUG: administration of Buccal midazolam in home group as a rescue medication for seizure control.|DRUG: administration of intramuscular midazolam in homegroup as a rescue medication for seizure control.|DRUG: administration of Nasal midazolam in ER group as a rescue medication for seizure control.|DRUG: administration of Buccal midazolam in ER group as a rescue medication for seizure control.|DRUG: administration of intramuscular midazolam in ER group as a rescue medication for seizure control.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Safety of UF-KURE19 Cells in Non-Hodgkin Lymphomas
Status: ACTIVE_NOT_RECRUITING
Conditions: Non Hodgkin Lymphoma
Interventions: BIOLOGICAL: UF-KURE19 CAR-T cells|DRUG: Fludarabine|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Green Tea and Salvadora Persica L. in Patients With Gingivitis
Status: RECRUITING
Conditions: Gingivitis
Interventions: DRUG: co.mouthwas|OTHER: Kin|OTHER: Distilled water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Feasibility of an Online Modeled Exposure in Spider Fearful Individuals
Status: RECRUITING
Conditions: Spider Fear|Arachnophobia
Interventions: BEHAVIORAL: online psychoeducation video + modeled exposure|BEHAVIORAL: live psychoeducation video + modeled exposure|BEHAVIORAL: group exposure|BEHAVIORAL: mental retrieval cue
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination of Steroid and Humanized CD25 Monoclonal Antibody as First-line Therapy for aGVHD
Status: NOT_YET_RECRUITING
Conditions: Acute Graft Versus Host Disease
Interventions: DRUG: CD25 antibody combined glucocorticoid as first-line treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tocilizumab for the Treatment of Familial Mediterranean Fever
Status: COMPLETED
Conditions: Familial Mediterranean Fever
Interventions: DRUG: Tocilizumab Infusion RoAcemtra (EU)|DRUG: 0.9% physiological saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: 2D Versus SonoAVC Scanning in High Responders
Status: UNKNOWN
Conditions: Infertility
Interventions: DEVICE: 2D ultrasound|DEVICE: SonoAVC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Study To Assess The Pharmacokinetics Of Different Modified Release Formulations Of GSK221149 In Healthy Adult Subjects
Status: TERMINATED
Conditions: Obstetric Labour, Premature|Premature Ejaculation
Interventions: DRUG: GSK221149
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study To Observe Safety And Blood Concentrations Of PF-06649751 During And Following The Oral Administration Of Multiple Doses Of PF-06649751 In Healthy Adult Western and Japanese Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: 0.15 mg PF-06649751|DRUG: 0.5 mg PF-06649751|DRUG: 0.5 mg PF-06649751|DRUG: 1.5 mg PF-06649751|DRUG: 1.5 mg PF-06649751 21 Days|DRUG: 3.0 mg PF-06649751|DRUG: 5.0 mg PF-06649751|DRUG: 8.0 mg PF-06649751|DRUG: 1.5 mg PF-06649751 in healthy Japanese subjects
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Single and Multiple Ascending Dose Study in Healthy Participants and Participants With an Autoimmune Disease
Status: RECRUITING
Conditions: Healthy Volunteers|Autoimmune Disease
Interventions: DRUG: LAD191|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Inhaled Nitric Oxide and Inhaled Prostacyclin After Cardiac Surgery for Heart Transplant or LVAD Placement
Status: COMPLETED
Conditions: Heart Failure
Interventions: DRUG: Nitric Oxide|DRUG: Prostacyclin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EGCG for the Prevention and Treatment of TIPN
Status: RECRUITING
Conditions: Chemotherapy-induced Peripheral Neuropathy
Interventions: DRUG: Epigallocatechin-3-Gallate|DRUG: Alcohol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ruxolitinib Phosphate to Treat Diffuse Large B-Cell or Peripheral T-Cell Non-Hodgkin Lymphoma After Stem Cell Transplant
Status: COMPLETED
Conditions: Recurrent Diffuse Large B-Cell Lymphoma|Recurrent Mature T- and NK-Cell Non-Hodgkin Lymphoma|Refractory Diffuse Large B-Cell Lymphoma|Refractory Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma
Interventions: OTHER: Laboratory Biomarker Analysis|DRUG: Ruxolitinib Phosphate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Pharmacodynamic Effect of Single Doses of MT-8554 in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: MT-8554 low dose|DRUG: MT-8554 high dose|DRUG: Oxycodone hydrochloride|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose:
Clinical trial: Trial to Evaluate the Efficacy of Simvastatin for Smoking Cessation
Status: COMPLETED
Conditions: Smoking Cessation
Interventions: DRUG: simvastatin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Can Neural Network Instability in Schizophrenia be Improved With a Very Low Carbohydrate Ketogenic Diet?
Status: RECRUITING
Conditions: Schizophrenia|Bipolar Disorder
Interventions: OTHER: Ketogenic diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Erector Spinae Plane Block for Postoperative Pain Control in Hip Replacement Surgeries
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: PROCEDURE: ultrasound-guided Erector spinae plane block|PROCEDURE: subarachonoid block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Protective Cooling Measures to Safeguard Elderly People From Dangerous Summer Heat
Status: NOT_YET_RECRUITING
Conditions: Hyperthermia|Heat; Weather|Aging|Type2 Diabetes|Hypertension|Heat Stress
Interventions: OTHER: No cooling (control)|OTHER: Recommended cooling|OTHER: Hybrid cooling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of Ixekizumab (LY2439821) in Chinese Participants With Moderate-to-Severe Plaque Psoriasis
Status: COMPLETED
Conditions: Plaque Psoriasis
Interventions: DRUG: Ixekizumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Cognitive-Behavioral Intervention Package on Procedural Pain and Anxiety in Children
Status: COMPLETED
Conditions: Procedural Anxiety|Procedural Pain
Interventions: BEHAVIORAL: Cognitive-Behavioral Interventions Package
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Improving the Mental Health of Resident Physicians and Fellows Through Transcendental Meditation
Status: WITHDRAWN
Conditions: Burnout, Professional|Stress, Psychological|Depression|Job Stress
Interventions: BEHAVIORAL: Transcendental meditation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Immunoscore in Rectal Cancer
Status: COMPLETED
Conditions: Cancer of the Rectum|Neoplasms, Rectal|Rectal Cancer|Rectal Tumors|Rectal Adenocarcinoma
Interventions: PROCEDURE: Diagnostic Biopsy and Surgical Procedure|PROCEDURE: Intravoxel incoherent motion MRI (IVIM)|PROCEDURE: Dynamic Contrast Enhanced MRI (DCE-MRI)|GENETIC: RNA gene expression analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of a Nutritional Support System for Improving Gross Motor Function in Cerebral Palsy
Status: COMPLETED
Conditions: Nutrition Disorder, Child|Gross Motor Development Delay|Neuro: Cerebral Palsy|Diet Modification|Probiotics
Interventions: DIETARY_SUPPLEMENT: Nutritional Support System (NSS)|OTHER: deworming|OTHER: recommended diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Exploratory Investigation of Dietary Supplementation and the Effect on Common Symptoms of Hormonal Imbalance
Status: COMPLETED
Conditions: Hormone Disturbance
Interventions: DIETARY_SUPPLEMENT: Semaine Hormonal Imbalance & The Daily
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: RiLuzole to Reduce Atrial FIb Study Using Holter Monitoring
Status: RECRUITING
Conditions: Atrial Fibrillation Paroxysmal
Interventions: DRUG: Riluzole 50 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Hemodynamic and Inflammatory Effects of Abrupt Versus Tapered Corticosteroid Discontinuation in Septic Shock
Status: TERMINATED
Conditions: Septic Shock
Interventions: DRUG: hydrocortisone|DRUG: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Symptom Management App for Children at the Early Stage of Cancer Survivorship and Their Caregivers
Status: ACTIVE_NOT_RECRUITING
Conditions: Oncology|Survivorship
Interventions: OTHER: Symptom management mobile health application with personalised support
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Beetroot Juice on Reducing Hypertension in Autosomal Dominant Polycystic Kidney Disease
Status: COMPLETED
Conditions: Autosomal Dominant Polycystic Kidney|Hypertension|Endothelial Dysfunction
Interventions: DIETARY_SUPPLEMENT: Beetroot juice|DIETARY_SUPPLEMENT: Nitrate-depleted beetroot juice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Liver SBRT in Combination With Immune Checkpoint Inhibition in Patients With Metastatic Non-small Cell Lung Cancer
Status: RECRUITING
Conditions: Liver Metastases|Non-small Cell Lung Cancer
Interventions: RADIATION: Liver SBRT|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adductor Canal Block Versus Femoral Nerve Block With Repeated Bolus Doses Arthroplasty
Status: COMPLETED
Conditions: Postoperative Pain|Functional Outcomes
Interventions: PROCEDURE: Adductor Canal Block|PROCEDURE: femoral nerve block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of Oncaspar® and Three Doses of Pegylated Recombinant Asparaginase in Adult Patients With Newly Diagnosed Acute Lymphoblastic Leukaemia
Status: TERMINATED
Conditions: Acute Lymphoblastic Leukaemia
Interventions: DRUG: Oncaspar|DRUG: PEG-rASNase
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bicillin L-A vs Placebo for the Treatment of Chronic, Plaque-Type Psoriasis Unresponsive to Topical Medications
Status: TERMINATED
Conditions: Psoriasis
Interventions: DRUG: Bicillin L-A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intraoperative Methylprednisolone and Sugammadex
Status: COMPLETED
Conditions: Neuromuscular Monitoring|Sugammadex Effect
Interventions: DEVICE: Neuromuscular monitorisation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SCREENING
Clinical trial: A Study of the Efficacy and Safety of the LEISH-F2 + MPL-SE Vaccine for Treatment of Cutaneous Leishmaniasis
Status: COMPLETED
Conditions: Cutaneous Leishmaniasis
Interventions: BIOLOGICAL: LEISH-F2 + MPL-SE|DRUG: Sodium stibogluconate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Epcoritamab and Rituximab for First-line Follicular Lymphoma
Status: RECRUITING
Conditions: Follicular Lymphoma|Low Grade Non-Hodgkin's Lymphoma, Adult
Interventions: DRUG: Epcoritamab|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of A Morning Dosing Of A New Medicine And Its Effects On Sleep At Bedtime In Subjects With Primary Insomnia
Status: COMPLETED
Conditions: Sleep Initiation and Maintenance Disorders|Insomnia
Interventions: DRUG: GW679769
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Dose Finding Posterolateral Thoracotomy Study
Status: TERMINATED
Conditions: Postoperative Pain
Interventions: DRUG: Low Dose SKY0402|DRUG: High Dose SKY0402|DRUG: Placebo|DRUG: Fentanyl via PCA|DRUG: Bupivacaine via epidural
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CTA101 UCAR-T Cell Injection for Treatment of Relapsed or Refractory CD19+ B-cell Acute Lymphoblastic Leukemia
Status: UNKNOWN
Conditions: Acute Lymphoblastic Leukemia
Interventions: BIOLOGICAL: CTA101
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Supporting the Health and Well-being of Children With Intellectual and Developmental Disability During COVID-19 Pandemic
Status: COMPLETED
Conditions: Covid19|Intellectual Disability|Developmental Disability|Child Development Disorder
Interventions: BEHAVIORAL: General Communication Message|BEHAVIORAL: Focused/Targeted Message|BEHAVIORAL: Best Message Alone|BEHAVIORAL: Best Message + Augmented Message or Implementation Strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Determination of the Minimal Clinically Important Difference After Treatment With Pantoprazole in Patients With Symptoms of Acid Reflux (Gastroesophageal Reflux Disease) (BY1023/M3-340)
Status: COMPLETED
Conditions: Gastroesophageal Reflux
Interventions: DRUG: Pantoprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Trial of 2 Step ATG for Acute GVHD Prevention Post Myeloablative Allogeneic Stem Cell Transplant
Status: NOT_YET_RECRUITING
Conditions: GVHD,Acute|Acute Leukemia|Myelodysplastic Syndromes|Myeloproliferative Disorders
Interventions: DRUG: ATG Combined with Tacrolimus and Mini Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of a Non-pharmacological Intervention to Prevent Delirium Among Elderly In-patients
Status: UNKNOWN
Conditions: Delirium
Interventions: DEVICE: Eyemask and earplugs|OTHER: Orientation about space and time
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: the Effect of Mixture of Natural Products As Salivary Substitutes in Treatment Of Xerostomia
Status: COMPLETED
Conditions: Sjogren's Syndrome|Xerostomia
Interventions: OTHER: natural herbs of coconut, aloe vera, and pepperint|OTHER: carboxy methyl cellulose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cisplatin and Gemcitabine Hydrochloride With or Without Berzosertib in Treating Patients With Metastatic Urothelial Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Bladder Urothelial Carcinoma|Metastatic Renal Pelvis and Ureter Urothelial Carcinoma|Metastatic Ureter Urothelial Carcinoma|Stage IV Bladder Urothelial Carcinoma AJCC v7
Interventions: DRUG: Berzosertib|DRUG: Cisplatin|DRUG: Gemcitabine Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Two on the Effectiveness of Mindfulness Training for Smokers
Status: COMPLETED
Conditions: Nicotine Dependence
Interventions: BEHAVIORAL: Integrated Training for Smokers|BEHAVIORAL: Mindfulness Training for Smokers|BEHAVIORAL: Quitline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: H. Pylori Eradication on Healing of Iatrogenic Gastric Ulcer by Endoscopic Mucosal Resection
Status: UNKNOWN
Conditions: Ulcer
Interventions: DRUG: Lansoprazole (proton pump inhibitor), amoxicillin, clarythromycin|DRUG: Lansoprazole (proton pump inhibitor), placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of 3DCRT Versus IGRT and Analysis of Early Response in Head and Neck Cancer.
Status: UNKNOWN
Conditions: HEAD AND NECK CANCER|CARCINOMA OROPHARYNX|CARCINOMA PYRIFORM SINUS|CARCINOMA LARYNX
Interventions: RADIATION: EPID Verification|RADIATION: CBCT verification
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study for Solid Tumor Patients Treated With Eltrombopag
Status: COMPLETED
Conditions: Thrombocytopaenia
Interventions: DRUG: Eltrombopag olamine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Outcomes After Perforator Flap Reconstruction for Breast Reconstruction and/or Lymphedema Treatment
Status: UNKNOWN
Conditions: Breast Cancer|Hereditary Breast/Ovarian Cancer (brca1, brca2)|Acquired Lymphedema|Congenital Lymphedema
Interventions: PROCEDURE: Perforator Flap Breast Reconstruction|PROCEDURE: Vascularized Lymph Node Transfer
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Photodynamic Therapy in Patients With Gingivitis
Status: COMPLETED
Conditions: Gingivitis|Orthodontic Appliance Complication|Photodynamic Therapy
Interventions: PROCEDURE: scaling and root planing (SRP) + PDT placebo|PROCEDURE: scaling and root planing (SRP) + PDT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: RP-6306 in Patients With Advanced Cancer
Status: RECRUITING
Conditions: Advanced Cancer
Interventions: DRUG: RP-6306|DRUG: Gemcitabine|DRUG: FOLFIRI Protocol|DRUG: Trastuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of TRS01 in Subjects With Active Non-infectious Anterior Uveitis Including Subjects With Uveitic Glaucoma
Status: COMPLETED
Conditions: Non-infectious Anterior Uveitis|Uveitic Glaucoma
Interventions: DRUG: TRS01|DRUG: FDA approved steroid eye drop (masked)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of a Low Residue Diet in Comparison to the Dietetic Recommendations From the INCan in Cervical Cancer Patients
Status: TERMINATED
Conditions: Uterine Cervical Neoplasm|Dietary Modification|Radiation Toxicity|Gastrointestinal Complication
Interventions: OTHER: Dietary modification
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Higher Volume and Lower Dose on Analgesic Quality During Labor Analgesia With Dural Puncture Epidural
Status: RECRUITING
Conditions: Analgesia
Interventions: PROCEDURE: Group I: Lower Volume with Higher Anaesthetic Concentration|PROCEDURE: Group II: Higher Volume with LowerAnaesthetic Concentration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase III of RRM1 & ERCC1 Directed Customized Chemotherapy for the Treatment of Patients With NSCLC
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: Docetaxel|DRUG: Vinorelbine|DRUG: Carboplatin|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial Comparing Mini-posterior Approach and Direct Anterior Approach
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: PROCEDURE: Mini-Posterior surgical approach for total hip arthroplasty|PROCEDURE: Direct Anterior surgical approach for total hip arthroplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimizing Vitamin D Status During Initial Military Training
Status: COMPLETED
Conditions: Bone Health|Nutrition Status
Interventions: DIETARY_SUPPLEMENT: Ca/Vit D|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Tranexamic Acid for Preventing Progressive Intracranial Haemorrhage in Traumatic Brain Injury
Status: COMPLETED
Conditions: Brain Injuries
Interventions: DRUG: tranexamic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vaccine Therapy in Patients With Stages IIIB/IV Non-Small Cell Lung Cancer Who Have Finished First-Line Chemotherapy
Status: TERMINATED
Conditions: Lung Cancer
Interventions: BIOLOGICAL: Allogeneic B7.1/HLA-A1|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: To Evaluate the Safety and Tolerability of SYHX2001 in Patients With Advanced or Metastatic Solid Tumors
Status: RECRUITING
Conditions: Advanced or Metastatic Solid Tumors
Interventions: DRUG: SYHX2001
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High Dose Versus Standard Dose of Ribavirin in Patients With Chronic Hepatitis C, Genotype 3
Status: COMPLETED
Conditions: Chronic Hepatitis C
Interventions: DRUG: Peginterferon alfa 2 A|DRUG: Peginterferon alfa 2 A, ribavirin + Epo Beta|DRUG: ribavirin|DRUG: ribavirin|DRUG: Peginterferon alfa 2|DRUG: ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Skin Responses and T Cell Immunology After House Dust Mite Exposure in Sensitized Atopic Dermatitis Patients
Status: COMPLETED
Conditions: Atopic Dermatitis|House Dust Mite Allergy
Interventions: DRUG: House Dust Mite Allergen|OTHER: Allergen-free air
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy of Oral Versus Intravenous Acetaminophen for Primary Pediatric Cleft Palate Repair
Status: COMPLETED
Conditions: Cleft Palate
Interventions: DRUG: Oral acetaminophen|DRUG: Ofirmev®|DRUG: Opioid only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dose-dependent Anti-inflammatory Effects of Vitamin D in a Human Gingivitis Model
Status: COMPLETED
Conditions: Gingivitis
Interventions: DRUG: vitamin D3|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Proof of Concept Study of Intravesical DTA-H19 in Patients With Superficial Bladder Cancer
Status: COMPLETED
Conditions: Bladder Neoplasms
Interventions: DRUG: DTA-H19
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Safety of 3% Povidone-Iodine in Acne Therapy
Status: UNKNOWN
Conditions: Acne
Interventions: DRUG: Repigel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Contingency Management and Nicotine Replacement Therapy on Youth Smoking
Status: COMPLETED
Conditions: Cigarette Smoking Behavior
Interventions: DRUG: Nicotine polacrilex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Primary Prevention of Gastric Varices Bleed
Status: WITHDRAWN
Conditions: Gastric Varices Bleeding|Endoscopic Ultrasound
Interventions: PROCEDURE: EUS-Guided Therapy of Glue and Coil|DRUG: Non-Selective Beta Blockers (Propanolol)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: No Stoma VS Ghost Stoma in Patients Undergoing Total Mesorectal Excision for Rectal Cancer
Status: NOT_YET_RECRUITING
Conditions: Rectal Neoplasms
Interventions: PROCEDURE: Ghost ileostomy|PROCEDURE: No ileostomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: External Beam Radiation Therapy and Cetuximab Followed by Irinotecan and Cetuximab for Children and Young Adults With Newly Diagnosed Diffuse Pontine Tumors and High-Grade Astrocytomas
Status: COMPLETED
Conditions: Brain Cancer
Interventions: OTHER: cetuximab in conjunction with external beam radiation therapy, followed by cetuximab and irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Oral Erdafitinib in People With Recurrent Non-Invasive Bladder Cancer
Status: RECRUITING
Conditions: Bladder Cancer|Recurrent Bladder Cancer|FGFR3 Gene Mutation
Interventions: DRUG: Erdafitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Histological Skin Changes of Different Peeling Agents in Surgically Subcutaneous Undermined Skin
Status: COMPLETED
Conditions: Burn of Face, Head and/or Neck|Peeling
Interventions: PROCEDURE: TCA 20% Peeling|PROCEDURE: Phenol/croton oil Peeling|PROCEDURE: TCA 40% Peeling
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of Azithromycin in the Prevention of Mycobacterium Avium Complex Disease (MAC) in HIV-Infected Patients
Status: COMPLETED
Conditions: Mycobacterium Avium-Intracellulare Infection|HIV Infections
Interventions: DRUG: Azithromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Comparative Study on Usability of Inhaler Devices in Adults With Asthma or COPD
Status: COMPLETED
Conditions: Asthma|COPD
Interventions: DEVICE: Spiromax (budesonide/formoterol)|DEVICE: Turbohaler (budesonide/formoterol)|DEVICE: Diskus(50mcg salmeterol &250/500 mcg fluticasone propionate)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of Different Concentrations of Carbamide as Moisturizers in Ichthyosis Vulgaris
Status: UNKNOWN
Conditions: Ichthyosis Vulgaris
Interventions: DEVICE: 7.5 %
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess Safety, Tolerability, Pharmacokinetic & Pharmacodynamic Effect of UCB5857 in Healthy & Psoriatic Subject
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: UCB5857 Part 1|DRUG: UCB5857 Part 2|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Multi-Country Observational Study to Collect the Frequency of Sexual Dysfunction With Antidepressant Treatment, Either With SSRIs or Duals at 8 Weeks and 6 Months
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: SSRIs|DRUG: Dual antidepressants
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Arthroscopic Bankart Repair Using Double Loaded Grand Knot Technique Versus Double Loaded Knotted Suture Anchor
Status: COMPLETED
Conditions: Arthroscopic Bankart Repair
Interventions: OTHER: double loaded knotted suture anchor|OTHER: double grand knot
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Digital Health Physical Activity Program for Older Family Care Partners of Patents With Heart Failure
Status: NOT_YET_RECRUITING
Conditions: Heart Failure|Caregiver Burden
Interventions: BEHAVIORAL: TPA4You|BEHAVIORAL: Attention control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Combination of Regorafenib and Nivolumab in Unresectable Hepatocellular Carcinoma
Status: COMPLETED
Conditions: Carcinoma, Hepatocellular|Hepatoma
Interventions: DRUG: Regorafenib/Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radiation Therapy to the Head or Intrathecal Chemotherapy Plus High Dose Cytarabine in Preventing CNS Disease in Children With Acute Lymphoblastic Leukemia
Status: WITHDRAWN
Conditions: Leukemia
Interventions: DRUG: asparaginase|DRUG: cyclophosphamide|DRUG: cytarabine|DRUG: daunorubicin hydrochloride|DRUG: mercaptopurine|DRUG: methotrexate|DRUG: prednisone|DRUG: therapeutic hydrocortisone|DRUG: vincristine sulfate|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Maintaining a Prone Position After Use of an Epidural Blood Patch for the Treatment of Post-dural Puncture Headache
Status: TERMINATED
Conditions: Post-Dural Puncture Headache
Interventions: OTHER: Prone position for 1 hour after blood patch|PROCEDURE: Blood patch
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION