pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Esthetics of Dental Composite and Adhesive System
Status: ACTIVE_NOT_RECRUITING
Conditions: Cavities of Teeth
Interventions: DIAGNOSTIC_TEST: Pulp vitality testing|OTHER: Photos|DRUG: local and/or topical anesthetic|DEVICE: rubber dam|OTHER: tooth surface cleaned|PROCEDURE: enamel margins|PROCEDURE: Adhesive Systems|PROCEDURE: cavity preparation|OTHER: Shade selection using Easy Shade 5|PROCEDURE: Light Curing|PROCEDURE: Contoured and polished|OTHER: Consent|OTHER: Health Questionnaire|RADIATION: xray|OTHER: Release of medical information signed|OTHER: Oral Exam|OTHER: Teeth Assessment|OTHER: Clinical Assessment|DEVICE: Tokuyama Universal Bond|DEVICE: ScotchBond
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: S0931, Everolimus in Treating Patients With Kidney Cancer Who Have Undergone Surgery
Status: ACTIVE_NOT_RECRUITING
Conditions: Kidney Cancer
Interventions: DRUG: everolimus|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Prospective Evaluation of Microwave Ablation (MWA) in the Treatment of Relapsed Graves' Disease
Status: RECRUITING
Conditions: Graves Disease|Minimally Invasive Treatment|Ablation Treatment
Interventions: DEVICE: Microwave ablation(MWA) device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intrapartum Epidural Fentanyl and Breast-feeding in the Immediate Postpartum Period: a Prospective Cohort Study
Status: WITHDRAWN
Conditions: Maternal Anaesthesia and Analgesia Affecting Fetus or Newborn|Breast Feeding|Fentanyl|Bupivacaine|Nalbuphine
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Relative Bioavailability, Safety, Tolerability, Pharmacokinetics (PK) and Food Effect Study of GSK2140944 in Healthy Subjects
Status: COMPLETED
Conditions: Infections, Bacterial
Interventions: DRUG: GSK2140944 capsule|DRUG: GSK2140944 tablet|DRUG: Itraconazole capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GSK2251052 in Complicated Urinary Tract Infection
Status: TERMINATED
Conditions: Infections, Urinary Tract
Interventions: DRUG: GSK2251052|DRUG: imipenem-cilastatin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Virtual Reality Hypno-sedation on Functional Recovery and Anxiety in Foot Surgery With Regional Anesthesia
Status: COMPLETED
Conditions: Foot Deformities|Regional Anesthesia Morbidity|Valgus; Hallux|Analgesia
Interventions: DEVICE: Hypnosedation|DRUG: Midazolam injection|DEVICE: Virtual reality
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Role of Lung Ultrasound and Pulsed-wave Doppler in Lung Consolidations in Mechanically Ventilated Patients
Status: RECRUITING
Conditions: Atelectasis|Pneumonia
Interventions: OTHER: Lung ultrasound and Doppler (Day 0)|OTHER: Lung ultrasound and Doppler (Day 0)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Regenerative Potential of a Collagen Membrane Associated or Not to Bovine Bone in Class II Furcation Defects.
Status: COMPLETED
Conditions: Periodontal Diseases|Bone Diseases
Interventions: PROCEDURE: guided tissue regeneration with using an absorbable collagen membrane associated with inorganic bovine bone associated.|PROCEDURE: guided tissue regeneration with using an absorbable collagen membrane associated or not with inorganic bovine bone associated with collagen matrix.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Virtual Parental Presence on Induction of Anesthesia vs Premedication With Midazolam
Status: NOT_YET_RECRUITING
Conditions: Anxiety|Surgery
Interventions: BEHAVIORAL: Virtual Parental Presence on Induction of Anesthesia|BEHAVIORAL: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Treatment of Chronic Fatigue Syndrome and Fibromyalgia With D-ribose- a Multicenter Study
Status: COMPLETED
Conditions: Fibromyalgia|Chronic Fatigue Syndrome
Interventions: DIETARY_SUPPLEMENT: Ribose
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vasopressin and Methylprednisolone for In-Hospital Cardiac Arrest
Status: COMPLETED
Conditions: Heart Arrest
Interventions: DRUG: Vasopressin, Arginine|DRUG: Methylprednisolone|DRUG: NaCl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Does a Multimodal no-Compression Suture Technique of the Intercostal Space Reduce Chronic Post-Thoracotomy Pain?
Status: COMPLETED
Conditions: Chronic Postoperative Pain
Interventions: PROCEDURE: intercostal muscle flap and pericostal no-compression suture|PROCEDURE: Standard suture technique of the intercostal space
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Systematic Evaluation of Antiviral Medication in Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder
Interventions: DRUG: Valacyclovir|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial of Ligation Plus Nadolol Versus Nadolol Alone in the Prophylaxis of First Variceal Bleeding in Cirrhosis
Status: COMPLETED
Conditions: Variceal Bleeding|Cirrhosis
Interventions: PROCEDURE: Ligation of varices|DRUG: Nadolol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Maintenance Regimen and Revised Regimen for Advanced Breast Cancer Survivors After First-line Salvage Therapy
Status: UNKNOWN
Conditions: Breast Cancer|Chemotherapy Effect|Disease-free Survival
Interventions: DRUG: Vinorelbine|DRUG: Gemcitabine|DRUG: Cisplatin|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Olanzapine and a Comparator in Patients With Schizophrenia and Schizoaffective Disorder
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder
Interventions: DRUG: olanzapine|DRUG: risperidone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Preferred Consent Models for Secondary Uses of Biospecimens Among Diverse Women
Status: COMPLETED
Conditions: Biospecimen Donation
Interventions: BEHAVIORAL: Study-specific consent model|BEHAVIORAL: Broad consent model|BEHAVIORAL: Notice consent model
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Nonpharmacologic Reduction of Periprocedural Pain and Anxiety in Dentistry
Status: WITHDRAWN
Conditions: Dental Anxiety|Dental Pain|Root Work
Interventions: OTHER: Comfort Talk® App|OTHER: Placebo App
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Safety Study of ARRY-371797 in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: ARRY-371797, p38 inhibitor; oral|DRUG: Placebo; oral
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Evaluation of 3D Rotational Angiography After EVAR
Status: WITHDRAWN
Conditions: Radiation Burn|Aortic Aneurysm, Abdominal
Interventions: RADIATION: 3D rotational angiography (3DRA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Acupuncture With Press Tack Needles for Perioperative Pain After Open Radical Prostatectomy
Status: COMPLETED
Conditions: Prostate Cancer|Perioperative Pain
Interventions: OTHER: Acupuncture|OTHER: Acupressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Modulation of SERCA2a of Intra-myocytic Calcium Trafficking in Heart Failure With Preserved Ejection Fraction
Status: RECRUITING
Conditions: Heart Failure, Diastolic|Heart Failure With Preserved Ejection Fraction
Interventions: BIOLOGICAL: AAV1/SERCA2a
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Active Elements of Digital Single-session Interventions
Status: ACTIVE_NOT_RECRUITING
Conditions: Depression
Interventions: BEHAVIORAL: Psychoeducation|BEHAVIORAL: Testimonials and Saying is believing exercises|BEHAVIORAL: Action planning|BEHAVIORAL: Breathing exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Healthy Prebiotic and Postbiotic Effects of Peanuts and Peanut Butter: College Intervention Trial
Status: COMPLETED
Conditions: Microbiota|Cognitive Change
Interventions: OTHER: Roasted peanuts (group A)|OTHER: Peanut butter (group B)|OTHER: Control (group C)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Anti-Cholinergic Receptors Antibodies, Autonomic Profile and Dysautonomia Symptoms in PAF, ALS and POTS (DISAUT-AB)
Status: COMPLETED
Conditions: Pure Autonomic Failure|Amyotrophic Lateral Sclerosis|Postural Orthostatic Tachycardia Syndrome|Anti-Cholinergic Receptors Antibodies
Interventions: PROCEDURE: Immunoabsorption/plasmapheresis procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Radiation Therapy With or Without Chemotherapy in Treating Patients With Stage II or Stage III Bladder Cancer
Status: COMPLETED
Conditions: Bladder Cancer
Interventions: DRUG: fluorouracil|DRUG: mitomycin C|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Early Progressive Feeding in Human-Milk Fed Extremely Preterm Infants: A Randomized Trial
Status: COMPLETED
Conditions: Premature; Infant, Light-for-dates
Interventions: OTHER: Progressive Feeding without MEF|OTHER: Progressive Feeding with MEF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: the Effect of Scapular Dyskinesia on the Scapular Balance Angle & Upper Extremity Sensorimotor Function in Spastic Stroke Patient. The Patients Were Diagnosed With the Lateral Scapular Slide Test, Fugl-Meyer Upper Extremity (FMUE) Scale Scores & Scapular Balance Angle Test (SBA).
Status: COMPLETED
Conditions: Post Stroke Scapular Dyskinesia
Interventions: OTHER: Assessment of scapular balance angle and upper extremity sensorimotor function
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Efficacy of Voxzogo for Growth Deficits in MPS IVA and VI
Status: RECRUITING
Conditions: MPS IVA|MPS VI
Interventions: DRUG: Vosoritide Injection [Voxzogo]
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: EptinezuMaB in ReAl-world evidenCE: Multicenter, Real Life, Cohort Study in Migraine.
Status: RECRUITING
Conditions: Migraine Disorders
Interventions: DRUG: Eptinezumab 100 mg or Eptinezumab 300 mg administered intravenously in 100 mL saline solution
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Soluble VE-cadherin and VE-cadherin Antibody in Sclerodermic Sclerosis
Status: COMPLETED
Conditions: Primary Raynaud Disease|Systemic Sclerosis
Interventions: BIOLOGICAL: soluble Ve cadherin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Successful Control and Clinical Effectiveness Of SERETIDE(Salmeterol/Fluticasone Propionate) Study In Asthma.(SUCCESS)
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Salmeterol/ fluticasone propionate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Follistatin Gene Transfer to Patients With Becker Muscular Dystrophy and Sporadic Inclusion Body Myositis
Status: COMPLETED
Conditions: Becker Muscular Dystrophy|Sporadic Inclusion Body Myositis
Interventions: BIOLOGICAL: rAAV1.CMV.huFollistatin344
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Safety and Efficacy Study Using Gene Therapy for Critical Limb Ischemia (NL003-CLI-III-2)
Status: COMPLETED
Conditions: Arterial Occlusive Disease|Ischemia|Ulcers|Peripheral Vascular Disease
Interventions: GENETIC: NL003|OTHER: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Outreach for Patients That Are Newly Eligible for Colorectal Cancer Screening
Status: TERMINATED
Conditions: Colorectal Cancer
Interventions: BEHAVIORAL: Letter Only|BEHAVIORAL: Letter and Educational DVD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Point of Care Testing for Advanced Practitioners (Paramedics)
Status: UNKNOWN
Conditions: Point of Care Testing|Clinical Decision-Making|Community Urgent & Emergency Care|Allied Health Professional
Interventions: DEVICE: Interventional Diagnostic Device Arm|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Effects of Dexmedetomidine on Delirium After Living Donor Renal Transplantation in Adult Patients
Status: UNKNOWN
Conditions: Postoperative Delirium After Living Donor Renal Transplantation
Interventions: DRUG: Dexmedetomidine|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Arthroscopic Superior Capsular Reconstruction - Study of Different Types of Grafts
Status: WITHDRAWN
Conditions: Rotator Cuff Tear|Graft Complication
Interventions: PROCEDURE: Arthroscopic superior capsular reconstruction
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Carbetocin Versus Syntometrine for Prevention of Postpartum Hemorrhage After Cesarean Section
Status: COMPLETED
Conditions: Postpartum Hemorrhage|Blood Loss
Interventions: DRUG: carbetocin|DRUG: Syntometrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of tDCS Montage on Measures of Appetite
Status: COMPLETED
Conditions: Eating Behavior
Interventions: DEVICE: new sham tDCS|DEVICE: real tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy Evaluation of VERU-111 for mCRPC in Patients Who Have Failed at Least One Androgen Receptor Targeting Agent
Status: TERMINATED
Conditions: Metastatic Castration-resistant Prostate Cancer|Androgen Resistant Prostatic Cancer
Interventions: DRUG: VERU-111|DRUG: Enzalutamide, Abiraterone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of the Mobile Application Developed for Families After the Earthquake on First Aid Knowledge and Burn Prevention
Status: COMPLETED
Conditions: Burns|First Aid|Mobile Application|Earthquake
Interventions: OTHER: Mobile application|OTHER: Family Information Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Epcoritamab Plus Ibrutinib for the Treatment of Relapsed or Refractory Aggressive B-Cell Non-Hodgkin Lymphoma
Status: NOT_YET_RECRUITING
Conditions: Recurrent Diffuse Large B-Cell Lymphoma|Recurrent Grade 3b Follicular Lymphoma|Recurrent High Grade B-Cell Lymphoma With MYC and BCL2 or BCL6 Rearrangements|Recurrent High Grade B-Cell Lymphoma With MYC, BCL2, and BCL6 Rearrangements|Recurrent High Grade B-Cell Lymphoma, Not Otherwise Specified|Recurrent Primary Mediastinal Large B-Cell Lymphoma|Recurrent Transformed Non-Hodgkin Lymphoma|Refractory Diffuse Large B-Cell Lymphoma|Refractory Grade 3b Follicular Lymphoma|Refractory High Grade B-Cell Lymphoma With MYC and BCL2 or BCL6 Rearrangements|Refractory High Grade B-Cell Lymphoma With MYC, BCL2, and BCL6 Rearrangements|Refractory High Grade B-Cell Lymphoma, Not Otherwise Specified|Refractory Primary Mediastinal Large B-Cell Lymphoma|Refractory Transformed Non-Hodgkin Lymphoma
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Bone Marrow Aspiration|PROCEDURE: Bone Marrow Biopsy|PROCEDURE: Computed Tomography|BIOLOGICAL: Epcoritamab|DRUG: Ibrutinib|PROCEDURE: Positron Emission Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vascular Impact of Dapagliflozin in CKD Patients (DAPAVASC)
Status: UNKNOWN
Conditions: Renal Insufficiency, Chronic
Interventions: DRUG: Dapagliflozin 10Mg Tab|DRUG: Placebo|PROCEDURE: impedance cardiography|PROCEDURE: Applanation tonometry|PROCEDURE: post-ischemic hyperemia of forearm|PROCEDURE: haemodynamics parameters
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Anti-BCMA CAR-NK Therapy in Relapsed or Refractory Multiple Myeloma
Status: NOT_YET_RECRUITING
Conditions: Multiple Myeloma, Refractory
Interventions: BIOLOGICAL: Anti-BCMA CAR-NK
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: IV Dose Study to Assess the Safety, Tolerability, PK, PD and Immunogenicity of ARGX-113 in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: BIOLOGICAL: ARGX-113|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Investigating the Combination of VB10.16 and Atezolizumab in Patients With HPV 16-positive Cervical Cancer
Status: COMPLETED
Conditions: Cervical Cancer|Cervix Cancer
Interventions: BIOLOGICAL: VB10.16|BIOLOGICAL: Atezolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of a Tele-rehabilitation Programme in Children With Burns: a Randomized Controlled Trial
Status: RECRUITING
Conditions: Burns|Tele-rehabilitation|Scar|Children
Interventions: BEHAVIORAL: tele-rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Personalizing Health Outcome in Epilepsy Now - An Introduction to Clinical Services
Status: UNKNOWN
Conditions: Medically Intractable Epilepsy
Interventions: BEHAVIORAL: Andrews/Reiter approach to epilepsy|BEHAVIORAL: Relaxation/Meditation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TOward a Better Understanding of the autoPhagy Machinery for the Identification of Potential Novel Biomarkers and Therapeutic Targets in Crohn's Disease - TOPIC Study
Status: NOT_YET_RECRUITING
Conditions: Crohn's Disease
Interventions: BIOLOGICAL: Blood samples|BIOLOGICAL: Stool simple|BIOLOGICAL: Ileocolonic biopsies
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Broncho-alveolar Lavage Under Noninvasive Ventilation With Propofol TCI in Patient With AHRF
Status: COMPLETED
Conditions: Respiratory Insufficiency
Interventions: DRUG: Propofol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Improving Sleep Quality in People With Insomnia
Status: COMPLETED
Conditions: Primary Insomnia|Psychophysiological Insomnia
Interventions: BEHAVIORAL: Sleep hygiene program|BEHAVIORAL: Sleep hypnosis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multivalent HPV (Human Papillomavirus) Vaccine Study in 16- to 26-Year Old Men and Women (V503-003)
Status: COMPLETED
Conditions: Genital Warts|Anal Cancer|Anal Intraepithelial Neoplasia
Interventions: BIOLOGICAL: 9vHPV Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Selective Prevention Transdiagnostic Intervention for At-risk Adolescents With Booster Sessions. (PROCARE+ 2.0)
Status: RECRUITING
Conditions: Anxiety Disorders and Symptoms Depressive Symptoms|Risk Factors (Rejection, Bullying/Cyberbullying, Addictions, Healthy Lifestyle Habits, Exam Stress Management, Ecoanxiety, Expressed Emotion)
Interventions: BEHAVIORAL: PROCARE+ 2.0 two booster sessions.|BEHAVIORAL: PROCARE+ 2.0 one booster session.|BEHAVIORAL: PROCARE+ 2.0 without booster sessions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: HELIOS-B: A Study to Evaluate Vutrisiran in Patients With Transthyretin Amyloidosis With Cardiomyopathy
Status: ACTIVE_NOT_RECRUITING
Conditions: Transthyretin Amyloidosis (ATTR) With Cardiomyopathy
Interventions: DRUG: Vutrisiran|DRUG: Sterile Normal Saline (0.9% NaCl)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Epstein-Barr Virus Implication in Peri-implantitis: Towards an Innovative Etiopathogenic Model.
Status: RECRUITING
Conditions: Peri-Implantitis
Interventions: PROCEDURE: peri implantitis sanitation surgery|OTHER: Care
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Alirocumab in Patients With Acute Myocardial Infarction
Status: COMPLETED
Conditions: Myocardial Infarction|Hypercholesterolemia
Interventions: DRUG: alirocumab|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Collaborative Solutions for Breaking up Sedentary Time in Black Older Adults With Type 2 Diabetes: The Interrupt Diabetes Study
Status: RECRUITING
Conditions: Cardiovascular Diseases|Type 2 Diabetes
Interventions: BEHAVIORAL: strategies to break up SB
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Intraventricular Catheter System for IVH
Status: RECRUITING
Conditions: Intraventricular Hemorrhage (IVH)
Interventions: DEVICE: IRRAflow® Active Fluid Exchange System|DEVICE: Traditional extraventricular drain|PROCEDURE: Non-contrast head CTs
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Low Frame Rate Fluoroscopy and Cine-angiography on Reducing Operator and Patient Dose
Status: UNKNOWN
Conditions: Stable Angina|Unstable Angina|Acute Coronary Syndrome
Interventions: RADIATION: Radiation: 15 FPS Cine 15 PPS|RADIATION: Radiation: 7.5 low Frame rate|RADIATION: Low Cine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Efficacy and Safety of Ciclesonide in Preschool Children With Asthma (2 to 6 Years) (BY9010/M1-207)
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Ciclesonide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose:
Clinical trial: Influence of Cannabidiol on Glucose Tolerance and The Gut Microbiota
Status: COMPLETED
Conditions: Diabetes
Interventions: DIETARY_SUPPLEMENT: Cannabidiol (CBD) powder formulation|DIETARY_SUPPLEMENT: Matching Placebo Cannabidiol (CBD) powder formulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Use of an Allograft Set-up (SclerFIX) as Replacement of Sclera Graft for Support of Enucleation Implant
Status: COMPLETED
Conditions: Enucleated; Eye|Eye Cancer
Interventions: BIOLOGICAL: SclerFIX
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Etoricoxib Versus Gabapentin for Knee Arthroscopy
Status: COMPLETED
Conditions: Knee Arthroscopy
Interventions: DRUG: Gabapentin, Etoricoxib, Sugar pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of ADR-001 in Patients With Severe Pneumonia Caused by SARS-CoV-2 Infection (COVID-19)
Status: COMPLETED
Conditions: SARS-CoV-2 Infection( COVID-19 )
Interventions: BIOLOGICAL: Mesenchymal stem cell|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Safety, Pharmacokinetics, Pharmacodynamics, and Immunogenicity of Ravulizumab in Chinese Adults Participants With Paroxysmal Nocturnal Hemoglobinuria (PNH)
Status: NOT_YET_RECRUITING
Conditions: Paroxysmal Nocturnal Hemoglobinuria|PNH
Interventions: DRUG: Ravulizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Darusentan Effect on PET Uptake Heterogeneity
Status: COMPLETED
Conditions: Coronary Artery Disease|Endothelial Dysfunction
Interventions: DRUG: darusentan 100 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Does the Threat of an Aversive Reaction Affect Craving of Alcohol During Cue Exposure in Alcohol Dependent Patients?
Status: COMPLETED
Conditions: Alcoholic Intoxication, Chronic
Interventions: BEHAVIORAL: Aversive reaction during alcohol cue exposure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Treating Tuberculosis Wasting With a High-protein Supplement
Status: TERMINATED
Conditions: Tuberculosis|Tuberculosis, Pulmonary|Undernutrition|Malnutrition
Interventions: DIETARY_SUPPLEMENT: Lacprodan® DI-8090
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevalence of COVID-19 in High Altitude : Insights From the Highest City of the World
Status: UNKNOWN
Conditions: Covid19|High Altitude
Interventions: DIAGNOSTIC_TEST: SARS-CoV-2 rapid diagnostic test (COVID-PRESTO® IgM/IgG, AAZ, Boulogne-Billancourt, France)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Does Treatment of Androgen Excess Using Spironolactone Improve Ovulatory Rates in Girls With Androgen Excess?
Status: RECRUITING
Conditions: Polycystic Ovary Syndrome|Puberty Disorders|Ovulation Disorder
Interventions: DRUG: Spironolactone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Balance, Aerobic Capacity, Mobility and Strength in Patients Hospitalized for Heart Failure (BAMS-HF) Program
Status: COMPLETED
Conditions: Heart Failure|Heart Failure With Preserved Ejection Fraction|Heart Failure, Systolic|Heart Failure, Diastolic|Heart Failure，Congestive|Heart Failure; With Decompensation|Heart Failure Acute|Heart Failure With Reduced Ejection Fraction
Interventions: BEHAVIORAL: BAMS-HF Program
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Multicenter, Randomized, Double-Blind, Double-Dummy Study Of Azithromycin SR Versus Amoxicillin For The Treatment Of Strep Throat In Children
Status: COMPLETED
Conditions: Tonsillitis
Interventions: DRUG: amoxicillin|DRUG: azithromycin SR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: IL13Ra2-CAR T Cells With or Without Nivolumab and Ipilimumab in Treating Patients With GBM
Status: RECRUITING
Conditions: Recurrent Glioblastoma|Refractory Glioblastoma
Interventions: BIOLOGICAL: IL13Ralpha2-specific Hinge-optimized 4-1BB-co-stimulatory CAR/Truncated CD19-expressing Autologous TN/MEM Cells|BIOLOGICAL: Ipilimumab|BIOLOGICAL: Nivolumab|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Safety of Therapeutic Treatment With an Immunomodulatory Agent (N-803) in Adults With COVID-19
Status: TERMINATED
Conditions: COVID-19
Interventions: BIOLOGICAL: N-803|OTHER: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: ALL2008 Protocol for Childhood Acute Lymphoblastic Leukemia (ALL) - 6MP Consolidation Therapy
Status: COMPLETED
Conditions: Acute Lymphoblastic Leukemia
Interventions: DRUG: 6MPindividualized|DRUG: 6MPfixed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Seltorexant as Adjunctive Therapy to Antidepressants in Adult and Elderly Participants With Major Depressive Disorder With Insomnia Symptoms Who Have Responded Inadequately to Antidepressant Therapy
Status: TERMINATED
Conditions: Depressive Disorder, Major
Interventions: DRUG: Seltorexant|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Posterior Extra-fascial RARP in Intermediate or High Risk Prostate Cancer
Status: NOT_YET_RECRUITING
Conditions: Surgical Procedure, Unspecified|Prostate Cancer
Interventions: PROCEDURE: Extrafascial robotic assisted radical prostatectomy via posterior approach|PROCEDURE: Extrafascial robotic assisted radical prostatectomy via anterior approach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigating the Efficacy of Low or High Dose Tart Cherry on Recovery From Exercise Induced Muscle Damage and Establishing Its Molecular Mechanisms of Action
Status: COMPLETED
Conditions: Muscle Recovery
Interventions: OTHER: 500 ml base solution|OTHER: 500 ml containing 30 ml tart cherry concentrate diluted with water and base solution|OTHER: 500 ml containing 60 ml tart cherry concentrate diluted with water only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Ketamine as an Adjunctive Therapy for Major Depression (2)
Status: ACTIVE_NOT_RECRUITING
Conditions: Major Depressive Episode|Unipolar Depression|Bipolar Depression
Interventions: DRUG: Ketamine|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Determine The Effect of a Drug Called Neupogen on Stroke Recovery
Status: UNKNOWN
Conditions: Ischemic Stroke
Interventions: DRUG: Filgrastim
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Metronidazole Hydrogel 25% in Stage II and III Periodontitis
Status: COMPLETED
Conditions: Periodontitis
Interventions: DRUG: metronidazole hydrogel|PROCEDURE: scaling and root planning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Aquatic Exercise for Cognition and Mobility in Older Adults
Status: COMPLETED
Conditions: Aging Well|Aging Problems|Cognitive Change|Gait, Unsteady|Mobility Limitation
Interventions: BEHAVIORAL: Aquatic Integrated Cognitive Motor Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Nutritional Supplement's Effects on Cognition
Status: RECRUITING
Conditions: Dietary Supplement|Cognition|Healthy
Interventions: DIETARY_SUPPLEMENT: Softgel Cognitive Formulation containing Astaxanthin, Grape Juice Extract and All Natural Vitamin E|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Combretastatin A4 Phosphate to Treat Patients With Choroidal Neovascularization Secondary to Pathologic Myopia
Status: COMPLETED
Conditions: Choroidal Neovascularization|Myopia, Degenerative
Interventions: DRUG: Combretastatin A-4 Phosphate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase IIb-III Study of BL-1020 Small Molecule for Schizophrenia
Status: TERMINATED
Conditions: Schizophrenia|Cognitive Effect on Schizophrenic Patients
Interventions: DRUG: CYP-1020|DRUG: Risperidone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Primary Care Internet Based Depression Prevention for Adolescents (CATCH-IT) Also Known as Promoting AdolescenT Health
Status: COMPLETED
Conditions: Major Depression|Depressive Episodes
Interventions: BEHAVIORAL: CATCH-IT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Supramaximal Titrated Inhibition of RAAS in Dilated Cardiomyopathy
Status: COMPLETED
Conditions: Dilated Cardiomyopathy
Interventions: DRUG: Benazepril|DRUG: Valsartan|DRUG: Metoprolol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PET/CT Imaging of Angiogenesis in Lung or Head and Neck Cancers Prior or During Chemotherapy With Antiangiogenic Agents
Status: TERMINATED
Conditions: Advanced Head and Neck Carcinoma|Advanced Non-small Cell Lung Carcinoma
Interventions: DRUG: radiopharmaceutical (Flotegatide (18F) or RGD (68Ga)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Radial Artery Patency and Bleeding, Efficacy, Adverse evenT Trial
Status: UNKNOWN
Conditions: Percutaneous Coronary Intervention
Interventions: DEVICE: 6Fr Glidesheath Slender sheath|DEVICE: 5Fr sheath|PROCEDURE: Hemostasis with TR band|PROCEDURE: Any hemostasis procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Neoadjuvant mFolfirinox With or Without Preoperative Concomitant Chemoradiotherapy in Patients With Borderline Resectable Pancreatic Carcinoma (PANDAS-PRODIGE 44)
Status: ACTIVE_NOT_RECRUITING
Conditions: Pancreatic Carcinoma
Interventions: DRUG: mFolfirinox|RADIATION: Chemoradiotherapy|PROCEDURE: surgery|DRUG: Adjuvant chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pain and Perceptual Distortion of Face
Status: COMPLETED
Conditions: Neuropathic Pain|Orofacial Pain
Interventions: DEVICE: Active repetitive transcranial magnetic stimulation (rTMS)|DEVICE: Sham repetitive transcranial magnetic stimulation (sham rTMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Randomized Prospective Trial on the Use of Laser Assisted Hatching (LAH) for Transfer of Frozen/Thawed Embryos in Human IVF/ICSI
Status: COMPLETED
Conditions: IVF|ICSI
Interventions: PROCEDURE: laser assisted hatching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Home Air Filtration for Traffic-Related Air Pollution
Status: RECRUITING
Conditions: Cardiovascular Risk Factor|Blood Pressure
Interventions: OTHER: HEPA Air Filtration|OTHER: Sham HEPA Air Filtration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Forodesine Hydrochloride in Patients With Advanced, Fludarabine-refractory Chronic Lymphocytic Leukemia (CLL)
Status: COMPLETED
Conditions: Leukemia, Lymphocytic, Chronic
Interventions: DRUG: forodesine hydrochloride (BCX-1777)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Carboplatin and Gemcitabine in Treating Patients With Locally Advanced or Metastatic Breast Cancer
Status: TERMINATED
Conditions: Breast Cancer
Interventions: DRUG: Carboplatin|DRUG: Gemcitabine Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Efficacy of Aromatherapy on the Well-being of Healthcare Professionals
Status: COMPLETED
Conditions: Healthcare Professionnals
Interventions: DIETARY_SUPPLEMENT: essentiel oil mixtures in inhaler sticks (step 1) - no intervention (step 2)|DIETARY_SUPPLEMENT: no intervention (step 1) - essential oils mixture in inhaler sticks (step 2)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Osimertinib With or Without Savolitinib as 1L in de Novo MET+, EGFR+ NSCLC
Status: ACTIVE_NOT_RECRUITING
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: Osimertinib|DRUG: Savolitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety and Immunogenicity of SARS-CoV-2 Vaccine (IN-B009) in Healthy Adults (COVID-19)
Status: UNKNOWN
Conditions: COVID-19
Interventions: BIOLOGICAL: IN-B009 (Low-dose)|BIOLOGICAL: IN-B009 (High-dose)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Iron Status and Cardiopulmonary Physiology
Status: COMPLETED
Conditions: Iron-deficiency|Ventricular Function|Pulmonary Vascular Resistance Abnormality|Altitude Hypoxia
Interventions: DRUG: Ferric Carboxymaltose Injectable Product|DRUG: Normal Saline 0.9% Infusion Solution Bag
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: High Intensity Interval Training and Technologies in COPD
Status: TERMINATED
Conditions: COPD
Interventions: OTHER: HIIT exercise program ABC|OTHER: HIIT exercise program CAB|OTHER: HIIT exercise program BCA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Platelet-rich Plasma (PRP) for Endometrial Regeneration and Repair
Status: TERMINATED
Conditions: Infertility|Asherman's Syndrome
Interventions: BIOLOGICAL: Intrauterine infusion of platelet rich plasma
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Evaluation of 3M Cavilon Advanced Barrier Film for the Treatment of Incontinence Associated Dermatitis (IAD)
Status: COMPLETED
Conditions: Dermatitis
Interventions: DEVICE: Cavilon Advanced Barrier Film
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Autologous Activated Adipose-derived Stem Cells (RB-ADSC) Injected Directly Into the Brain for Mild to Moderate Alzheimer's Disease
Status: RECRUITING
Conditions: Alzheimer Disease
Interventions: BIOLOGICAL: RB-ADSC
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efatutazone Dihydrochloride in Treating Patients With Previously Treated Myxoid Liposarcoma That Cannot Be Removed by Surgery
Status: COMPLETED
Conditions: Liposarcoma
Interventions: DRUG: efatutazone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Medication for Nonallergic Rhinitis (NAR) Based on Cluster Analysis
Status: UNKNOWN
Conditions: Determination of the Efficacy of Different Medications for Idiopathic Rhinitis|Impact of Different Medications on Biomarkers of Idiopathic Rhinitis|Safety and Tolerance of Different Medications for Idiopathic Rhinitis
Interventions: DRUG: Budesonide Nasal Spray (Rhinocort, Shanghai Johnson & Johnson Pharmaceuticals, Ltd.)|DRUG: Levocabastine Nasal Spray (Livostine, Shanghai Johnson & Johnson Pharmaceuticals, Ltd.)|DRUG: 0.9% natural saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vinorelbine and Paclitaxel Plus Radiation Therapy in Treating Patients With Advanced Cancer Arising in the Pelvis
Status: COMPLETED
Conditions: Bladder Cancer|Cervical Cancer|Endometrial Cancer|Vaginal Cancer
Interventions: DRUG: paclitaxel|DRUG: vinorelbine tartrate|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II of Lenvatinib Plus PD-1 Antibody for Advanced HCC
Status: WITHDRAWN
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Lenvatinib|DRUG: PD-1 antibody
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Core Stabilization Exercises in People With Chronic Low Back Pain
Status: UNKNOWN
Conditions: Non-speciﬁc Low Back Pain
Interventions: OTHER: Core Exercise Group|OTHER: Routine Therapy Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate NRCT-101SR in Adult Attention Deficit Hyperactivity Disorder (ADHD)
Status: COMPLETED
Conditions: ADHD
Interventions: DRUG: NRCT-101-SR|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Regional Ventilation Using 19F MRI of Inert Perfluorinated Gases Mixed With Oxygen
Status: COMPLETED
Conditions: COPD|Asthma|Cystic Fibrosis|Emphysema|Small Airways Diseases
Interventions: DRUG: perfluorinated gas/oxygen mixture
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Pain Neuroscience Education, Motor Imagery and Action Observation in Patients With Chronic Temporomandibular Disorders.
Status: RECRUITING
Conditions: TMD
Interventions: OTHER: Occlusal Splint (OS).|OTHER: Pain Neuroscience Education (PNE).|OTHER: Motor Imagery (MI).|OTHER: Action Observation (AO).|OTHER: Jaw and Neck Exercises (JNE)|OTHER: Counselling.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Jessener Solution Versus Intralesional Steroid in Treatment of Alopecia Areata
Status: UNKNOWN
Conditions: Alopecia Areata
Interventions: DRUG: Corticosteroids Acting Locally
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT