pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Study to Assess Etoricoxib Versus Diclofenac in Chinese Patients With Osteoarthritis of the Knee or Hip (0663-080)(COMPLETED)
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DRUG: MK0663; etoricoxib / Duration of Treatment:4 Weeks|DRUG: Comparator: diclofenac sodium tablet 75 mg / Duration of Treatment:4 Weeks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Complete Surgery of Colorectal Deep Infiltrating Endometriosis on Fertility
Status: RECRUITING
Conditions: Endometriosis|Infertility
Interventions: PROCEDURE: complete surgery|PROCEDURE: In vitro fertilization without surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trephination in Arthroscopic Cuff Repair: a Prospective Randomized Controlled
Status: COMPLETED
Conditions: Rotator Cuff Tear
Interventions: PROCEDURE: Bone Trephination|PROCEDURE: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective Data Collection of Patients < 6 Months of Age Undergoing Thoracoscopic Surgery
Status: COMPLETED
Conditions: Congenital Diaphragmatic Hernia|Tracheoesophageal Fistula|Esophageal Atresia
Interventions: PROCEDURE: Thoracoscopic surgery
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of GLP-1 on Postprandial Lipid Metabolism
Status: UNKNOWN
Conditions: Heart Disease
Interventions: DRUG: Exendin-9|DRUG: GLP-1|OTHER: saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Phase IB/II Trial Combining Vinorelbine With Sorafenib as First-Line Treatment in Patients With Metastatic Breast Cancer
Status: UNKNOWN
Conditions: Metastatic Breast Cancer
Interventions: DRUG: Sorafenib and Vinorelbine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testosterone Regulation of the Natriuretic Peptide System
Status: WITHDRAWN
Conditions: Hypertension
Interventions: DRUG: Testosterone|DRUG: Nesiritide|DRUG: Leuprolide|DRUG: Anastrozole|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of JNJ-38877618 in Healthy Male Participants
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: JNJ-38877618: Part 1a|DRUG: JNJ-38877618: Part 1b|DRUG: JNJ-38877618: Part 1c (optional)|DRUG: JNJ-38877618: Part 2|DRUG: JNJ-38877618: Part 3|DRUG: JNJ-38877618: Part 4 (optional)|DRUG: Placebo: Parts 1a, 2, 3, and 4 (optional)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: B-type Natriuretic Peptide (BNP) in Human Hypertension
Status: TERMINATED
Conditions: Hypertension Stage 1
Interventions: DRUG: brain natriuretic peptide|OTHER: no-added salt diet
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Vaccine (Ad5.F35-hGCC-PADRE) for the Treatment of Gastrointestinal Adenocarcinoma
Status: SUSPENDED
Conditions: Pancreatic Ductal Adenocarcinoma|Colorectal Adenocarcinoma|Gastric Adenocarcinoma|Clinical Stage II Gastric Cancer AJCC v8|Clinical Stage IIA Gastric Cancer AJCC v8|Clinical Stage IIB Esophageal Adenocarcinoma AJCC v8|Clinical Stage IIB Gastric Cancer AJCC v8|Clinical Stage III Esophageal Adenocarcinoma AJCC v8|Clinical Stage III Gastric Cancer AJCC v8|Malignant Solid Neoplasm|Pathologic Stage II Gastric Cancer AJCC v8|Pathologic Stage IIB Esophageal Adenocarcinoma AJCC v8|Pathologic Stage IIB Gastric Cancer AJCC v8|Pathologic Stage III Esophageal Adenocarcinoma AJCC v8|Pathologic Stage III Gastric Cancer AJCC v8|Pathologic Stage IIIA Esophageal Adenocarcinoma AJCC v8|Pathologic Stage IIIB Esophageal Adenocarcinoma AJCC v8|Pathologic Stage IIIA Gastric Cancer AJCC v8|Pathologic Stage IIIB Gastric Cancer AJCC v8|Pathologic Stage IIIC Gastric Cancer AJCC v8|Stage I Pancreatic Cancer AJCC v8|Stage IA Pancreatic Cancer AJCC v8|Stage IB Pancreatic Cancer AJCC v8|Stage II Pancreatic Cancer AJCC v8|Stage IIA Pancreatic Cancer AJCC v8|Stage IIB Pancreatic Cancer AJCC v8|Stage III Colorectal Cancer AJCC v8|Stage III Pancreatic Cancer AJCC v8|Stage IIIA Colorectal Cancer AJCC v8|Stage IIIB Colorectal Cancer AJCC v8|Stage IIIC Colorectal Cancer AJCC v8|Stage IV Colorectal Cancer AJCC v8|Stage IVA Colorectal Cancer AJCC v8|Stage IVB Colorectal Cancer AJCC v8|Malignant Digestive System Neoplasm|Small Intestinal Adenocarcinoma|Stage III Small Intestinal Adenocarcinoma AJCC v8|Stage IIIA Small Intestinal Adenocarcinoma AJCC v8
Interventions: BIOLOGICAL: Adenovirus 5/F35-Human Guanylyl Cyclase C-PADRE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MAnnitol for Blood Pressure Stability in HemoDialysis (MAP-HD)
Status: RECRUITING
Conditions: Hemodialysis Complication|Hemodynamic Instability
Interventions: DRUG: Mannitol|DRUG: 0.9% saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Efficacy of Extra- Versus Intrafascial Injection for Supraclavicular Brachial Plexus Block
Status: COMPLETED
Conditions: Upper Extremity Problem
Interventions: PROCEDURE: Extrafascial injection|PROCEDURE: Intrafascial injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Bioavailability and Safety of DNL343 in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: DNL343|DRUG: Placebo|DRUG: DNL343
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Immersive Audiovisual Distraction Impact on Peroperative Opioid Consumption.
Status: COMPLETED
Conditions: Surgical Procedure, Unspecified|Analgesia|Outpatient
Interventions: DEVICE: Audiovisual distraction device|DEVICE: Analgesia nociception index
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neurotoxicity of Spinal Anesthesia With Ropivacaine and Bupivacaine
Status: UNKNOWN
Conditions: Anesthesia; Adverse Effect, Spinal and Epidural|Anaesthetic Complication Neurological
Interventions: DRUG: Ropivacaine|DRUG: Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: AWAITS: A Web-based E-health Application for Active Illicit Opioid Users
Status: COMPLETED
Conditions: Opioid-use Disorder|IV Drug Usage|Overdose|Drug Addiction|Substance Use Disorders
Interventions: OTHER: self-administered, e-health application
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Sugammadex Provide Better Surgical Condition Compared With Neostigmine in Laryngeal Microsurgery.
Status: COMPLETED
Conditions: Neuromuscular Blockade
Interventions: OTHER: Injection of neostigmine or sugammadex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Locomotor Training With Testosterone to Promote Bone and Muscle Health After Spinal Cord Injury
Status: RECRUITING
Conditions: Spinal Cord Injury|Spinal Cord Injuries|Trauma, Nervous System|Wounds and Injury|Central Nervous System Diseases|Spinal Cord Diseases|Gonadal Disorders|Endocrine System Diseases|Hypogonadism|Genital Diseases, Male|Spinal Cord Trauma|Injuries, Spinal Cord|Walking, Difficulty|Gait Disorders, Neurologic|Locomotion Disorder, Neurologic|Wounds and Injuries|Nervous System Diseases|Testosterone Deficiency|Androgen Deficiency|Hormone Deficiency
Interventions: DRUG: Testosterone Enanthate|BEHAVIORAL: Locomotor Training
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Gut and Azithromycin Mechanisms in Infants and Children II
Status: COMPLETED
Conditions: Malaria
Interventions: DRUG: Azithromycin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating the Relative Bioavailability and Food Effect of a Tablet Formulation of VX-147
Status: COMPLETED
Conditions: Focal Segmental Glomerulosclerosis (FSGS)
Interventions: DRUG: VX-147
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aloud Real-time Reading of ICU Diaries for Prevention of Negative Post-ICU Psychological Outcomes
Status: COMPLETED
Conditions: Anxiety|Depression|PTSD
Interventions: OTHER: Aloud Real-time Reading of ICU Diaries
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Phase III Clinical Study of Benvitimod Cream in the Treatment of Mild to Moderate Atopic Dermatitis
Status: UNKNOWN
Conditions: Atopic Dermatitis
Interventions: DRUG: Benvitimod Cream|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Interactions of Candesartan Cilexetil and Amlodipine Besylate
Status: UNKNOWN
Conditions: Healthy
Interventions: DRUG: candesartan cilexetil 32mg, amlodipine 10mg|DRUG: candesartan cilexetil 32mg, amlodipine 10mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Guided Imagery and Progressive Muscle Relaxation as a Means to Improve the Psychological Well-being and the Quality of Life for Patients With Breast and Prostate Cancer
Status: COMPLETED
Conditions: Breast Cancer|Prostate Cancer
Interventions: OTHER: Guided Imagery and Progressive Muscle Relaxation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Phase I/II Study of DYP688 in Patients With Metastatic Uveal Melanoma and Other GNAQ/11 Mutant Melanomas
Status: RECRUITING
Conditions: Metastatic Uveal Melanoma
Interventions: DRUG: DYP688
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multicenter Study of the Safety and Performance of Fabian-PRICO for Saturation Targeting Routine Use in the NICU
Status: COMPLETED
Conditions: Respiratory Insufficiency in Children
Interventions: DEVICE: fabian HFO, fabian +nCPAP evolution and fabian Therapy evolution with PRICO function|OTHER: Manual Control
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Combination Chemotherapy in Treating Patients With Metastatic Colorectal Cancer That Cannot Be Removed By Surgery
Status: UNKNOWN
Conditions: Colorectal Cancer
Interventions: DRUG: fluorouracil|DRUG: leucovorin calcium|DRUG: oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Permanent Skin Flora of Children Who Had Bathing With Two Different Products
Status: UNKNOWN
Conditions: Skin Microbiota
Interventions: OTHER: 2% chlorhexidine gluconate|OTHER: soap-free body cleaning solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Characterizing Successful Myopic Multifocal Contact Lens Wearers
Status: TERMINATED
Conditions: Visual Acuity
Interventions: DEVICE: Acuvue Moist Multifocal Contact Lens JJVC Marketed Contact Lens
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Topical Minoxidil Versus Topical Glyceryl Trinitrate in Treatment of Chronic Anal Fissure
Status: COMPLETED
Conditions: Anal Fissure
Interventions: DRUG: Minoxidil|DRUG: Glyceryl trinitrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Leucine-enriched Branched-chain Amino Acid on Muscle Thickness, Interleukin-6, SOFA Score in Critical Illness
Status: COMPLETED
Conditions: Critical Illness|Muscle Wasting
Interventions: DIETARY_SUPPLEMENT: BCAA|OTHER: Standard nutrition|OTHER: Standard physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of Vascular Endothelial Growth Factor (VEGF) Inhibition in Patients With Unilateral Upper Extremity Lymphedema Following Treatment for Cancer
Status: COMPLETED
Conditions: Lymphedema
Interventions: DRUG: Pazopanib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Efficacy of Synchronized Transcranial Magnetic Stimulation for the Treatment of Generalized Anxiety Disorder
Status: WITHDRAWN
Conditions: Generalized Anxiety Disorder (GAD)
Interventions: DEVICE: synchronized Transcranial Magnetic Stimulation (sTMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Sutureless and Glue Free Versus Sutured Limbal Conjunctival Autograft in Primary Pterygium Surgery
Status: COMPLETED
Conditions: Pterygium
Interventions: PROCEDURE: Sutureless and glue free limbal conjunctival autograft|PROCEDURE: Sutured limbal conjunctival autograft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Fasting Versus Non-fasting on Outcomes and Satisfaction Prior to Cardiac Catheterization
Status: COMPLETED
Conditions: Heart Diseases
Interventions: PROCEDURE: Coronary angiogram|PROCEDURE: Right heart catheterization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Mental Health Prevention Among Preschool Children Using a Culturally Adapted Version of ICPS
Status: UNKNOWN
Conditions: Mental Health|Aggressive Childhood Behavior|Problem Behavior|Social Behavior
Interventions: BEHAVIORAL: I Can Problem Solve (ICPS) Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Taste, Smell and Chemotherapy (TASTY)
Status: COMPLETED
Conditions: Testicular Cancer
Interventions: PROCEDURE: Dexa scan|PROCEDURE: audiogram|PROCEDURE: measurement of heart rate variability and baroreflex sensitivity|PROCEDURE: Glucose tolerance assessment|DIETARY_SUPPLEMENT: oral nutrition supplements|BEHAVIORAL: Two day food records|BEHAVIORAL: Food Frequency Questionnaire
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Ulonivirine (MK-8507) in Participants With Mild or Moderate Hepatic Impairment (MK-8507-014)
Status: NOT_YET_RECRUITING
Conditions: Hepatic Insufficiency
Interventions: DRUG: Ulonivirine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fecal Microbiota Transplantation as a Treatment for Ulcerative Colitis
Status: TERMINATED
Conditions: Ulcerative Colitis
Interventions: PROCEDURE: Colonoscopy|PROCEDURE: Gastroscopy|DRUG: Fecal Microbiota|PROCEDURE: Enema
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bismuth Quadruple Therapy With Cefuroxime for Helicobacter Pylori Eradication Treatment
Status: SUSPENDED
Conditions: Helicobacter Pylori Infection
Interventions: DRUG: Cefuroxime containing bismuth quadruple treatment|DRUG: Classic bismuth quadruple treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acute Glycemic Effects of Crackers Made by Different Flours
Status: COMPLETED
Conditions: Potential Abnormality of Glucose Tolerance|Appetitive Behavior
Interventions: OTHER: Glucose as reference food|OTHER: Cracker made by wheat flour|OTHER: Cracker made by rye flour|OTHER: Cracker made by sunflower flour
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Calgary Model Motivational Interviewing for Parents of Children With CP Care Burden Self-efficacy Coping With Stress
Status: RECRUITING
Conditions: Cerebral Palsy
Interventions: DIAGNOSTIC_TEST: MOTIVATIONAL INTERVIEW BASED ON THE CALGARY FAMILY INTERVENTION MODEL IN PARENTS WITH A CHILD WITH CEREBRAL PALS.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: 0.9% Saline Versus Balanced Solutions in Severe Diabetic Ketoacidosis
Status: COMPLETED
Conditions: Metabolic Ketoacidosis|Ketoacidemia|Acetonemia|Acetonuria
Interventions: DRUG: Sodium chloride 0.9% (SC)|DRUG: Ringer lactate (RL)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of Prayer on Conditioned Pain Modulation and on Pain Intensity in Healthy Religious University Students
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: BEHAVIORAL: Prayer|BEHAVIORAL: Reading a poem
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Evaluate the Efficacy and Safety of IBI305 in Patients With Advanced or Recurrent Non-squamous NSCLC
Status: COMPLETED
Conditions: NSCLC
Interventions: DRUG: Bevacizumab in Combination With Paclitaxel/Carboplatin|DRUG: IBI305 in Combination with Paclitaxel/Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Amikacin Pharmacokinetic Profile in Plasma and Tissue After an Administration Using Impregnated Dressings in Burned Patient Population
Status: TERMINATED
Conditions: Burn Patients
Interventions: DRUG: Treatment with Amikacin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: rTMS Plus CCFES-mediated Functional Task Practice for Severe Stroke
Status: RECRUITING
Conditions: Stroke|Hemiplegia|Cerebrovascular Accident (CVA)|Hemiparesis
Interventions: DEVICE: Contralaterally Controlled Functional Electrical Stimulation|DEVICE: New rTMS approach|DEVICE: Conventional rTMS approach|DEVICE: Sham rTMS approach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess Pharmacokinetic Exposures Following Intravenous and Subcutaneous Administration of Risankizumab in Healthy Participants
Status: RECRUITING
Conditions: Healthy Volunteers
Interventions: DRUG: Risankizumab|DRUG: Risankizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of SGN-B7H4V in Advanced Solid Tumors
Status: RECRUITING
Conditions: Ovarian Neoplasms|Peritoneal Neoplasms|Fallopian Tube Neoplasms|Triple Negative Breast Neoplasms|HER2 Negative Breast Neoplasms|Hormone Receptor Positive Breast Neoplasms|Endometrial Neoplasms|Carcinoma, Non-Small-Cell Lung|Cholangiocarcinoma|Gallbladder Carcinoma|Adenoid Cystic Carcinoma
Interventions: DRUG: SGN-B7H4V
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimized vs. Standard Automated Peritoneal Dialysis Regimens Study
Status: COMPLETED
Conditions: End Stage Kidney Disease|Chronic Kidney Disease Requiring Chronic Dialysis
Interventions: PROCEDURE: Automated peritoneal dialysis (APD)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Targeting Physical Health in Schizophrenia: Physical Activity Can Enhance Life Randomized Control Trial
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder|Brief Psychotic Disorder|Schizophreniform Disorders|Unspecified Schizophrenia Spectrum and Other Psychotic Disorder
Interventions: BEHAVIORAL: PACE-Life|BEHAVIORAL: Exercise Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rapid Ventricular Pacing in Surgical Treatment of Intracranial Aneurysms
Status: UNKNOWN
Conditions: Intracranial Aneurysm|Surgical Clip
Interventions: PROCEDURE: Rapid Ventricular Pacing
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Intra-articular Resiniferatoxin to Treat Moderate to Severe Pain From Knee Osteoarthritis
Status: ACTIVE_NOT_RECRUITING
Conditions: Osteoarthritis, Knee|Knee Osteoarthritis|Knee Pain Chronic
Interventions: DRUG: Resiniferatoxin|DRUG: Zilretta|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nab-Paclitaxel Plus Gemcitabine With Concurrent MR-Guided IMRT in Patients With Locally Advanced Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DRUG: nab-Paclitaxel|DRUG: Gemcitabine|RADIATION: Intensity modulated radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prolonged Exposure Versus Treatment as Usual in Chronic Posttraumatic Stress Disorder Combat and Terror Related Patients
Status: COMPLETED
Conditions: Posttraumatic Stress Disorder
Interventions: BEHAVIORAL: Prolonged Exposure (PE) therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose:
Clinical trial: Glimepiride 4 mg Tablets Under Non-Fasting Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Glimepiride 4 mg Tablets|DRUG: AMARYL® 4 mg Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Durvalumab ± Tremelimumab in Combination With Platinum Based Chemotherapy in Untreated Extensive-Stage Small Cell Lung Cancer (CASPIAN)
Status: ACTIVE_NOT_RECRUITING
Conditions: Small Cell Lung Carcinoma Extensive Disease
Interventions: DRUG: Durvalumab|DRUG: Tremelimumab|DRUG: Carboplatin|DRUG: Cisplatin|DRUG: Etoposide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose-Ranging Study of Mometasone Furoate (MK-0887/SCH 032088) Nasal Spray in the Treatment of Children (Ages 6-11) With Seasonal Allergic Rhinitis (C95-161)
Status: COMPLETED
Conditions: Rhinitis, Allergic, Seasonal
Interventions: DRUG: Mometasone furoate nasal spray|DRUG: Beclomethasone dipropionate nasal spray|DRUG: Placebo nasal spray|DRUG: Chlorpheniramine maleate syrup
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Japan Phase 2/3 Clinical Study With BLM-240 (Desflurane)
Status: COMPLETED
Conditions: Anesthesia
Interventions: DRUG: desflurane|DRUG: desflurane/nitrous oxide|DRUG: sevoflurane/nitrous oxide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Integrated-Delivery-of-Care Approach to Improve Patient Outcomes, Safety, Well-Being After Orthopaedic Trauma
Status: COMPLETED
Conditions: Musculoskeletal Injury Trauma
Interventions: PROCEDURE: Integrated care (ICare)|PROCEDURE: Usual Care (UsCare)|OTHER: Patient-Reported Outcomes Measurement Information System|OTHER: Lower Extremity Gain Scale (LEGS)|OTHER: Dynamometer|OTHER: Active Range of Motion (AROM)|OTHER: Posttraumatic Stress Disorder (PTSD)|OTHER: Beck Depression Inventory-II|OTHER: State-Trait Anxiety Inventory (STAI)|OTHER: Tampa Scale of Kinesiophobia-11 (TSK-11)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Radiolabeled Monoclonal Antibody in Treating Patients With Progressive Metastatic Androgen-Independent Adenocarcinoma (Cancer) of the Prostate
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: RADIATION: lutetium Lu 177 monoclonal antibody J591
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare Daratumumab, Bortezomib, and Dexamethasone (DVd) vs Bortezomib and Dexamethasone (Vd) in Chinese Participants With Relapsed or Refractory Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Daratumumab|DRUG: Velcade|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Accelerated TMS for Focal Hand Dystonia
Status: RECRUITING
Conditions: Isolated Focal Hand Dystonia
Interventions: DEVICE: Transcranial Magnetic Stimulation (TMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Overcoming Nicotine Dependence to Enable Quitting
Status: RECRUITING
Conditions: Tobacco Use|Smoking Cessation|Smoking Behaviors|Nicotine Dependence|Nicotine Withdrawal
Interventions: DRUG: Nicotine Replacement Therapy (NRT) Sampling|BEHAVIORAL: Practice Quitting (PQ) Counseling|BEHAVIORAL: Motivational Interviewing (MI) Counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combined Effects of Plyometric and Endurance Training Among Female Hockey Players
Status: RECRUITING
Conditions: Plyometric Exercise|Endurance Training|Hockey
Interventions: OTHER: Combined Plyometric and Endurance Training|OTHER: Plyometric Training|OTHER: Endurance training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Safety Study to Examine the Systemic Exposure of Granexin® Gel After Topical Application to Venous Leg Ulcers
Status: COMPLETED
Conditions: Venous Leg Ulcer
Interventions: DRUG: Granexin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fecal Microbiota Transplantation in Severe Alcoholic Hepatitis- Assessment of Impact on Prognosis and Short-term Outcome
Status: UNKNOWN
Conditions: Severe Alcoholic Hepatitis
Interventions: OTHER: Fecal Microbiota Transplantation|OTHER: Standard of care treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cue Effects in Human Addiction: Pavlovian to Instrumental Transfer
Status: RECRUITING
Conditions: Alcohol Use Disorder (AUD)|Alcoholism|Substance Use Disorders|Smoking, Tobacco|Stress Reaction|Stress
Interventions: BIOLOGICAL: fMRI imaging (BOLD)|BIOLOGICAL: sMRI (structure)|BEHAVIORAL: Trier Social Stress Test|BEHAVIORAL: PIT paradigm|BEHAVIORAL: Counting Stroop task|BEHAVIORAL: No-go Simon task|DIAGNOSTIC_TEST: Stop Signal Task|DIAGNOSTIC_TEST: blood samples|DIAGNOSTIC_TEST: questionnaires for chronic stress|DIAGNOSTIC_TEST: hair samples|DIAGNOSTIC_TEST: saliva samples|DIAGNOSTIC_TEST: EMA assessment|DIAGNOSTIC_TEST: clinical diagnostic
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: MiDura-Study (Neuro-Patch in Duraplasty)
Status: RECRUITING
Conditions: Meningioma|Tumor, Brain|Chiari Malformation|Vascular Malformation|Hydrocephalus|Tethered Cord|Dural Fistula|Craniotomy|Spinal Surgery|Duraplasty
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Oxygen Therapy for Patients With Precapillary Pulmonary Hypertension Who Experience an Altitude Related Adverse Health Effect (ARAHE) During 30h Exposure to 2500m
Status: COMPLETED
Conditions: High Altitude Pulmonary Hypertension|Oxygen Therapy
Interventions: OTHER: Oxygen Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Primary Care and Parenting
Status: COMPLETED
Conditions: Parenting|Knowledge, Attitudes, Practice|Development, Child
Interventions: BEHAVIORAL: Sit Down and Play|OTHER: Handout
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Minimally Invasive Evaluation of Dyspepsia by Combined Magnetically Controlled Capsule Endoscopy and Urea Breath Test: a Pilot Prospective Cohort Study
Status: COMPLETED
Conditions: Dyspepsia|Peptic Ulcer Disease|Gastroesophageal Reflux|Ugi Malignancies|Pancreatobiliary Disease
Interventions: PROCEDURE: MCCE
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: To Show the Safety and Effectiveness of the Demetech Barbed Polydioxanone (PDO) Suture
Status: COMPLETED
Conditions: Wrinkle
Interventions: DEVICE: Demetech Barbed PDO Suture
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testing the Addition of an Immunotherapy Drug, Cemiplimab (REGN2810), Plus Surgery to the Usual Surgery Alone for Treating Advanced Skin Cancer
Status: NOT_YET_RECRUITING
Conditions: Recurrent Cutaneous Squamous Cell Carcinoma of the Head and Neck|Recurrent Skin Squamous Cell Carcinoma|Resectable Cutaneous Squamous Cell Carcinoma of the Head and Neck|Resectable Skin Squamous Cell Carcinoma|Stage III Cutaneous Squamous Cell Carcinoma of the Head and Neck AJCC v8|Stage IV Cutaneous Squamous Cell Carcinoma of the Head and Neck AJCC v8
Interventions: PROCEDURE: Biospecimen Collection|BIOLOGICAL: Cemiplimab|PROCEDURE: Computed Tomography|RADIATION: Image Guided Radiation Therapy|RADIATION: Intensity-Modulated Radiation Therapy|PROCEDURE: Magnetic Resonance Imaging|PROCEDURE: Positron Emission Tomography|OTHER: Questionnaire Administration|PROCEDURE: Surgical Procedure|PROCEDURE: Surgical Procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Safety and Effectiveness of the VRS100 System in PCI (ESSENCE)
Status: NOT_YET_RECRUITING
Conditions: Coronary Artery Disease|Cardiovascular Diseases|Coronary Disease|Myocardial Ischemia|Arteriosclerosis|Vascular Disease Occlusive
Interventions: PROCEDURE: VRS100 robotic-assisted PCI|PROCEDURE: Manual PCI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized Phase II Basket Trial EXTENDing Efficacy of Systemic Therapy With Local Consolidative Therapy for OligoProgressive Metastatic Disease (EXTEND-OP)
Status: RECRUITING
Conditions: OligoProgressive Metastatic Disease
Interventions: PROCEDURE: Local Consolidation Therapy|PROCEDURE: Next-line Systemic Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Empagliflozin on Functional Capacity in Heart Failure With Preserved Ejection Fraction
Status: COMPLETED
Conditions: Heart Failure With Preserved Ejection Fraction|Heart Failure, Diastolic|Diabetes Mellitus
Interventions: DRUG: Empagliflozin 10 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ANALYSIS OF INFLAMMATORY REACTIONS OBSERVED IN BRONCHOALVEOLAR LAVAGES (BALS)
Status: UNKNOWN
Conditions: Lung Cancer
Interventions: OTHER: treatment with immunotherapy and diffuse infiltrative lung disease|OTHER: Patients requiring carcinologic lobectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Safety and Efficacy Study Using ABT-335 (Investigational Drug) in Combination With Atorvastatin, to Study the Effects on Thickening of the Blood Vessel Wall in Patients With Abnormal Lipid (Fat) Levels in the Blood
Status: COMPLETED
Conditions: Coronary Artery Disease|Coronary Heart Disease|Dyslipidemia
Interventions: DRUG: ABT-335|DRUG: Placebo|OTHER: Atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study on Efficacy and Safety of Givinostat Versus Hydroxyurea in Patients With Polycythemia Vera
Status: RECRUITING
Conditions: Polycythemia Vera
Interventions: DRUG: Givinostat|DRUG: Hydroxyurea
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: LB-100, Carboplatin, Etoposide, and Atezolizumab for the Treatment of Untreated Extensive-Stage Small Cell Lung Cancer
Status: RECRUITING
Conditions: Extensive Stage Lung Small Cell Carcinoma
Interventions: DRUG: Atezolizumab|DRUG: Carboplatin|DRUG: Etoposide|DRUG: Protein Phosphatase 2A Inhibitor LB-100
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Effectiveness of Body Fat Distribution Imaging in Real-World Practice: The BODY-REAL Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Overweight and Obesity|PreDiabetes|Type 2 Diabetes|Cardiovascular Risk Factor
Interventions: DIAGNOSTIC_TEST: Body Fat Distribution Imaging Report|DIAGNOSTIC_TEST: Basic Weight Information|BEHAVIORAL: Patient Provided|BEHAVIORAL: Physician Provided
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Clinical Study of Behavior Problems in Children After Different Anesthesia Methods
Status: UNKNOWN
Conditions: Child Behavior|Problem Behavior
Interventions: PROCEDURE: TIVA|PROCEDURE: Sevoflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: A SAD Study of ZT002 Injection in Healthy Participants
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: ZT002|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Investigation to Demonstrate the Performance of a New Enema (TF037) in Distal Bowel Cleansing Compared With Fleet Enema
Status: COMPLETED
Conditions: Colonoscopy
Interventions: DEVICE: TF037|DRUG: Fleet enema
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Dual-benefits of Aerobic and Resistance Training
Status: SUSPENDED
Conditions: Sarcopenia|Aging|Disability Physical
Interventions: BEHAVIORAL: Resistance Training|BEHAVIORAL: Moderate-Intensity Continuous Cycling|BEHAVIORAL: High-Intensity Interval Cycling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: mHealth Mindfulness Intervention for Pregnant Black and Latina Women at Risk of Postpartum Depression
Status: ENROLLING_BY_INVITATION
Conditions: Post Partum Depression|Perinatal Depression
Interventions: BEHAVIORAL: Stress reduction program 'A'|BEHAVIORAL: Stress reduction program 'B'
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Application of Lactobacillus Salivarius CECT5713 in Infertility of Unknown Origin
Status: COMPLETED
Conditions: Abortion, Spontaneous|Abortion in First Trimester|Infertility Unexplained
Interventions: BIOLOGICAL: Lactobacillus salivarius CECT5713
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Telementoring Intervention (ECHO) for the Transformation of Professional Engagement, Practice Efficiency, and Community Building Through Team Meetings in Diagnostic Imaging Clinicians
Status: ACTIVE_NOT_RECRUITING
Conditions: Hematopoietic and Lymphoid Cell Neoplasm|Malignant Solid Neoplasm
Interventions: OTHER: Communication Intervention|OTHER: Questionnaire Administration|OTHER: Waiting List
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Web-based Educational Intervention on Breastfeeding Self-efficacy and Breastfeeding Outcome
Status: COMPLETED
Conditions: Breast Feeding|Self Efficacy|Feeding Behavior
Interventions: OTHER: Web-based educational program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Safety, and Immunogenicity of Two Influenza Vaccines in Healthy Subjects 3 to 64 Years Old
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Influenza virus vaccine|BIOLOGICAL: Comparator influenza vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Validation of X-ray Protocols in Cleft Children
Status: COMPLETED
Conditions: Evaluate CBCT Protocols in Subjective Image Quality
Interventions: RADIATION: Ultra-low dose protocol|RADIATION: Standard dose protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Efectiveness of Donor IL-15-stimulated NK Cells Post Transplant Infusion in in Acute Leukemia
Status: COMPLETED
Conditions: ACUTE LEUKEMIA
Interventions: BIOLOGICAL: Donor IL-15 stimulated NK cells infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Contribution of Wine Components on Hydroxytyrosol Body Concentrations and Biological Effects
Status: COMPLETED
Conditions: Contribution of Wine Components in Hydroxytyrosol Formation
Interventions: DIETARY_SUPPLEMENT: Ethanol|OTHER: Water|DIETARY_SUPPLEMENT: Alcoholized wine|DIETARY_SUPPLEMENT: De-alcoholized wine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Atezolizumab Plus Bevacizumab With HCC and HBV Infection
Status: ACTIVE_NOT_RECRUITING
Conditions: Carcinoma, Hepatocellular
Interventions: DRUG: Atezolizumab|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Marshall Ethanolization, Pulmonary Vein Isolation and Line Completion for Ablation of Persistent Atrial Fibrillation
Status: RECRUITING
Conditions: Atrial Fibrillation
Interventions: PROCEDURE: Destruction of Marshall bundles|PROCEDURE: Pulmonary veins isolation|PROCEDURE: Linear ablation in the left and right atria
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Identification of Gene Expression Signature for Panitumumab Sensitivity in Untreated Locally Advanced SCCHN
Status: TERMINATED
Conditions: Squamous Cell Carcinoma of the Head and Neck
Interventions: DRUG: Panitumumab|PROCEDURE: Surgery|PROCEDURE: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant TAC Plus or Minus Bevacizumab(AVF3299)
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Bevacizumab 7.5 and TAC|DRUG: Placebo 7.5 and Docetaxel, Doxorubicin, and Cyclophosphamide (TAC)|DRUG: Bevacizumab 15 and TAC|DRUG: Placebo 15 and TAC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Non-Invasive Neurostimulation of the Vagus Nerve With the AlphaCore Device for the Relief of EIB
Status: WITHDRAWN
Conditions: Asthma
Interventions: DEVICE: AlphaCore Device|DEVICE: AlphaCore
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pelvic Proprioceptive Neuromuscular Facilitation (PNF) Exercises in Multiple Sclerosis Patients
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: OTHER: Pelvic Pnf exercises|OTHER: Strength exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Low Level Laser Therapy Versus Pharmacotherapy in in Improving Masticatory Muscle Pain
Status: UNKNOWN
Conditions: TMD
Interventions: RADIATION: low level laser therapy|DRUG: Naproxen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Probiotic on Comorbidity of Depression and Constipation
Status: UNKNOWN
Conditions: Comorbidity of Depression and Constipation
Interventions: DIETARY_SUPPLEMENT: Probiotic|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Repair of Challenging Abdominal Wall Defects: Strattice(TM) TM in Abdominal Wall Repair (StAR)
Status: TERMINATED
Conditions: Hernia|Surgical Wound Dehiscence
Interventions: DEVICE: Strattice(TM) Reconstructive Tissue Matrix|PROCEDURE: Suture/suture with absorbable mesh
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Supragingival Plaque Removal With and Without Dentifrice
Status: COMPLETED
Conditions: Dental Plaque
Interventions: OTHER: Toothbrushing With Dentifrice|OTHER: Toothbrushing Without Dentifrice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of (Doravirine / Lamivudine / Tenofovir Disoproxil Fumarate) (Delstrigo®) as a New Strategy for Non-occupational Post Exposure Prophylaxis, a Prospective Open Label Study
Status: UNKNOWN
Conditions: Hiv
Interventions: DRUG: Delstrigo
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Novel Bidirectional Peripheral Artery Cannula in Minimally Invasive Aortic Valve Surgery
Status: UNKNOWN
Conditions: Efficacy and Safety of Novel Bidirectional Cannula
Interventions: DEVICE: Novel bidirectional cannula (BiflowTM, LivaNova, Italy)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Acupuncture on Pre-operative Anxiety Levels in Neurosurgical Patients: a Randomised, Controlled Trail
Status: COMPLETED
Conditions: Anxiety
Interventions: OTHER: Acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A 7-Day Cross-over Study of QD (Once Daily) and BID (Twice Daily) TD-4208 in Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease|COPD
Interventions: DRUG: TD-4208|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II Study of Adjuvant SIB Radiotherapy Following Narrow-Margin Hepatectomy in Patients With HCC.
Status: RECRUITING
Conditions: Hepatocellular Carcinoma|Narrow Margin|Radiotherapy
Interventions: RADIATION: Adjuvant SIB radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Gender Affirming Hormone Therapy on Glucose Metabolism
Status: RECRUITING
Conditions: Transgender Persons
Interventions: DRUG: Botnia Clamp|OTHER: Withdrawal of Gender Affirming Hormone Therapy (GAHT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE