pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Comparative Effects of Action Observation and Motor Imagery on Upper Limb in Chronic Stroke Patients
Status: COMPLETED
Conditions: Stroke|Upper Extremity Paresis|Motor Activity
Interventions: OTHER: action observation training|OTHER: motor imagery training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nerve Sparing Radical Hysterectomy VS Radical Hysterectomy: Safety and Clinical Efficacy
Status: UNKNOWN
Conditions: Cervical Cancer
Interventions: PROCEDURE: nerve sparing radical hysterectomy|PROCEDURE: radical hysterectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Acupuncture on Opioid-associated Constipation in Cancer Patients
Status: RECRUITING
Conditions: Opioid-associated Constipation in Cancer Patients
Interventions: OTHER: electro-acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of BMS-986195 Combined With an Oral Contraceptive (Ethinyl Estradiol/Norethindrone) in Healthy Female Patients
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: BMS-986195|DRUG: Loestrin 1.5/30 (1.5 mg norethindrone acetate/30 μg ethinyl estradiol)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MLN9708 (Ixazomib) in Combination With Panobinostat and Dexamethasone in Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma|Kahler Disease|Plasma-Cell Myeloma|Myelomatosis
Interventions: DRUG: Panobinostat|DRUG: Dexamethasone|DRUG: MLN9708
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Evaluation of Shenfu Injection to Reduce Myocardial Injury
Status: UNKNOWN
Conditions: Myocardial Infarction
Interventions: DRUG: Shenfu Injection|DRUG: 5% Glucose Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Epicatechin on Functional Capacity, Skeletal Muscle Structure and Diastolic Function in Patients With Heart Failure With Preserved Ejection Fraction (HFPEF)
Status: COMPLETED
Conditions: Heart Failure
Interventions: DIETARY_SUPPLEMENT: CocoaVia
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preventing Malnutrition Among Older Adults
Status: ACTIVE_NOT_RECRUITING
Conditions: Malnutrition
Interventions: OTHER: Education video
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: INTACT Trial - an Observational Study to Assess Neuropathy in Diabetic Children
Status: NOT_YET_RECRUITING
Conditions: Diabetes Mellitus
Interventions: DIAGNOSTIC_TEST: uroflowmetry|DIAGNOSTIC_TEST: Cardiovascular autonomic dysfunction test proposed by Ewing et al.|DIAGNOSTIC_TEST: peripheral nerve conduction test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effects of Anesthetics on Brain Network Connectivity in Patients With Supratentorial Glioma
Status: RECRUITING
Conditions: Brain Network Connectivity|Postoperative Delirium|Dexmedetomidine|Propofol
Interventions: DRUG: Dexmedetomidine|DRUG: Propofol
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Real-world Analysis of Concomitant Medication Use Among Metastatic Breast Cancer Patients Treated With CDK4/6 Inhibitors
Status: COMPLETED
Conditions: Metastatic Breast Cancer
Interventions: DRUG: Ribiciclib|DRUG: Palbociclib|DRUG: Abemaciclib
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Omega-3 Docosapentaenoic Acid on Lipids and Other Risk Factors for Cardiovascular Disease
Status: TERMINATED
Conditions: Elevated Triglycerides|Cardiovascular Risk Factor
Interventions: DIETARY_SUPPLEMENT: DPA enriched n-3|DIETARY_SUPPLEMENT: n-3 control|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of Oxidative Stress Changes in Different Ventilation Strategies During Gynecologic Laparoscopic Surgery
Status: COMPLETED
Conditions: Reperfusion Injury|Oxidative Stress
Interventions: PROCEDURE: Volume-controlled ventilation|PROCEDURE: Pressure-controlled ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Dissecting the Cellular and Molecular Atlas of Rheumatoid Arthritis in Sustained Remission to Identify Pathways Maintaining Remission and Triggering Flares
Status: RECRUITING
Conditions: Rheumatoid Arthritis
Interventions: OTHER: Tapering and/or discontinuation of treatment based on AI-guidance|OTHER: No tapering and/or discontinuation of treatment based on AI-guidance|OTHER: Tapering and/or discontinuation of treatment based on standard of care|OTHER: No tapering and/or discontinuation of treatment based on standard of care
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Efficacy Study of TNX-102 SL in Patients With Military-related PTSD
Status: TERMINATED
Conditions: PTSD
Interventions: DRUG: TNX-102 SL|DRUG: Placebo SL Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Relapsed Low-Grade or Follicular Lymphoma With Rituximab (Also Known as Rituxan, IDEC-C2B8, IDEC-102)
Status: COMPLETED
Conditions: Low-Grade or Follicular B-Cell Non-Hodgkin's Lymphoma
Interventions: DRUG: rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Brain Imaging and Behavioural Changes Following Cued-movement Training of Finger Sequences in Healthy Older Adults
Status: RECRUITING
Conditions: Aging|Music|Motor Activity|Magnetic Resonance Imaging|Neuronal Plasticity
Interventions: BEHAVIORAL: Music-cued audiovisual motor training|BEHAVIORAL: Visually-cued motor training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of MIL62 Combined With Orelabrutinib for the Treatment of R/R CD20+B Cell Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: B-cell Lymphoma Recurrent|B-cell Lymphoma Refractory
Interventions: DRUG: Orelabrutinib|DRUG: Recombinant humanized monoclonal antibody MIL62 injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Fucoxanthin on the Metabolic Syndrome, Insulin Sensitivity and Insulin Secretion
Status: ACTIVE_NOT_RECRUITING
Conditions: Metabolic Syndrome
Interventions: DRUG: Fucoxanthin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An Open-Label, Single-Center Study Evaluating the Effect of Systane Balance on Video Ocular Protection Index (OPI) and Blink Patterns in Patients Diagnosed With Dry Eye
Status: COMPLETED
Conditions: Dry Eye Syndrome
Interventions: OTHER: SYSTANE® Balance Lubricant Eye Drops
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety of Astepro 0.15% Nasal Spray and Astepro 0.1% Nasal Spray in Children Ages >6 Months to <6 Years With AR
Status: COMPLETED
Conditions: Allergic Rhinitis
Interventions: DRUG: 205.5 mcg of azelastine hydrochloride|DRUG: 137 mcg of azelastine hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I Dose Escalation Study of CD19/CD22 Chimeric Antigen Receptor (CAR) T Cells in Children and Young Adults With Recurrent or Refractory B Cell Malignancies
Status: RECRUITING
Conditions: B Acute Lymphoblastic Leukemia|CD19 Positive|Minimal Residual Disease|Philadelphia Chromosome Positive|Recurrent Adult Acute Lymphoblastic Leukemia|Recurrent Childhood Acute Lymphoblastic Leukemia|Refractory Acute Lymphoblastic Leukemia
Interventions: BIOLOGICAL: Chimeric Antigen Receptor T-Cell Therapy|DRUG: Cyclophosphamide|DRUG: Fludarabine Phosphate|OTHER: Laboratory Biomarker Analysis|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neural Mechanisms of Meditation Training in Healthy and Depressed Adolescents: An MRI Connectome Study PART 2
Status: RECRUITING
Conditions: Depression Mild|Depression Moderate|Depression, Teen
Interventions: BEHAVIORAL: TARA|BEHAVIORAL: Psycho-Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of Phase2, IMC-001 In Patients With Metastatic Or Locally Advanced TMB-H Solid Tumor
Status: NOT_YET_RECRUITING
Conditions: TMB-H|Histologically or Cytologically Proven Metastatic or Locally Advanced Solid Tumors
Interventions: DRUG: IMC-001
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Scalp Cooling to Prevent Chemo-induced Hair Loss
Status: UNKNOWN
Conditions: Breast Cancer|Alopecia
Interventions: DEVICE: PAXMAN Orbis Scalp Cooler|OTHER: Control No treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: The Study Of Probe-Based Confocal Laser Endomicroscopy Of Distal Airways In Diagnostics Of Lung Diseases
Status: UNKNOWN
Conditions: Inflammatory, Interstitial, Rare Lung Diseases
Interventions: DEVICE: miniprobe Alveoflex
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Advancing HPV Vaccination Among HIV Positive Adults: The CHAMPS Study
Status: RECRUITING
Conditions: Human Papilloma Virus|Human Papilloma Virus Vaccine
Interventions: BEHAVIORAL: CDC 4 Pillars Program
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparison of Complement Factors and Genetic Polymorphisms of AMD Between Patients With Systemic Lupus Erythematosus (SLE) With and Without Retinal "Pseudo-drusen-like" Deposits: Case-control Study (PL-AMD)
Status: COMPLETED
Conditions: Lupus Erythematosus|Lupus Erythematosus, Systemic|Age Related Macular Degeneration
Interventions: PROCEDURE: Blood test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Chlorhydrate of Ropivacaine and Breast Cancer Surgery
Status: COMPLETED
Conditions: Breast Neoplasms|Pain,Postoperative
Interventions: DRUG: Chlorhydrate de Ropivacaine|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of an Eccentric Muscle Strengthening Protocol on Force Moment, Muscle Activation and Plantar Flexor Structure of Patients With Central Nervous System Injuries.
Status: NOT_YET_RECRUITING
Conditions: Spinal Cord Injured|Post-stroke
Interventions: OTHER: muscle-strengthening program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical and Radiographic Outcomes of Class II Furcation Defects Management Using Propolis: A Case Series
Status: RECRUITING
Conditions: Furcation Defects
Interventions: DRUG: class II furcation defects management using propolis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study to Evaluate the Efficacy and Safety of of DR10624 in Subjects With Severe Hypertriglyceridemia
Status: RECRUITING
Conditions: Severe Hypertriglyceridemia
Interventions: DRUG: DR10624 Injection|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of ECE PEDO (Equipment for Clever Exercise) on Abdominal Obesity
Status: COMPLETED
Conditions: Obesity, Abdominal|Physical Activity
Interventions: OTHER: Supervised treadmill group (Group I)|DEVICE: ECE PEDO pedometer (Group II)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transurethral Resection and Combination Chemotherapy in Treating Patients With Stage II or Stage III Bladder Cancer
Status: TERMINATED
Conditions: Bladder Cancer
Interventions: BIOLOGICAL: filgrastim|DRUG: cisplatin|DRUG: doxorubicin hydrochloride|DRUG: methotrexate|DRUG: vinblastine sulfate|PROCEDURE: surgical procedure|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Pregnancies Outcomes in Advanced Maternal Age Women
Status: NOT_YET_RECRUITING
Conditions: Advanced Maternal Age Pregnancy|Premature|Labor Complication|Delivery Complication|Delivery Complications Affecting Fetus / Newborn|Delivery;Complicated;Liveborn|Cesarean Section Complications|Complication of Labor and Delivery
Interventions: PROCEDURE: spontaneous delivery
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of a Rheumatoid Arthritis Self-management Program
Status: COMPLETED
Conditions: Arthritis, Rheumatoid
Interventions: BEHAVIORAL: rheumatoid arthritis self-management program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Upper Extremity Theraband Exercises in Intensive Care Patients
Status: COMPLETED
Conditions: Exercise|Intensive Care Unit Patients
Interventions: OTHER: Theraband Exercises plus Conventional Physiotherapy and Rehabilitation Program|OTHER: Conventional Physiotherapy and Rehabilitation Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Recombinant Interferon Alpha and Etoposide in Relapsed Osteosarcoma
Status: COMPLETED
Conditions: Osteosarcoma
Interventions: DRUG: Etoposide|DRUG: Interferon Alpha
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Functional MRI Study: Assessing Brain Function in Post Stoke Patients
Status: WITHDRAWN
Conditions: Ischemic Stroke|Stroke|Acute Ischemic Stroke
Interventions: DEVICE: NeuroGlove
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Clinical Evaluation of Four Aesthetic Restorations in Non-carious Cervical Lesions
Status: WITHDRAWN
Conditions: Noncarious Cervical Lesions
Interventions: OTHER: EQUIA Forte Fil|OTHER: Clearfil Majesty Esthetic|OTHER: NexComp Flow|OTHER: 3M Espe Bulk-fill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Efficacy and Safety of Surgical Device "Lymphoblock" for Prevention of Lymphorrhea in Patients With Thoracoabdominal Aorta Repair.
Status: RECRUITING
Conditions: Aorta Abdominalis; Aneurysm|Aorta Thoracic; Aneurysm
Interventions: DEVICE: Lymphoblock|DEVICE: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Randomized Control Trial of Hip Dislocation Techniques for Pediatric Patients With Cerebral Palsy
Status: WITHDRAWN
Conditions: Hip Dysplasia|Cerebral Palsy
Interventions: PROCEDURE: Proximal Femoral Resection Arthroplasty|PROCEDURE: Subtrochanteric Valgus Osteotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of E2609 in Healthy Subjects and an Elderly Cohort
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: Drug: E2609|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial of an Integrated Clinic-community Intervention in Children and Adolescents With Obesity (Hearts and Parks)
Status: COMPLETED
Conditions: Childhood Obesity|Pediatric Obesity|Quality of Life|Cardiovascular Risk Factor
Interventions: BEHAVIORAL: Hearts & Parks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Relenvatinib in the Tatment of Recurrence of Hepatocellular Carcinoma After Liver Transplantation
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma|Liver Transplantation
Interventions: DRUG: relenvatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Breastfeeding Support on Exclusive Breastfeeding, Occurrence of Breast Problems and Breastfeeding Self-Efficacy
Status: COMPLETED
Conditions: Breastfeeding|Breastfeeding, Exclusive
Interventions: OTHER: Breastfeeding support and Booklet containing information about breastfeeding|OTHER: Booklet containing information about breastfeeding
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Test Whether Different Doses of BI 690517 Alone or in Combination With Empagliflozin Improve Kidney Function in People With Chronic Kidney Disease
Status: COMPLETED
Conditions: Kidney Disease, Chronic
Interventions: DRUG: BI 690517|DRUG: Placebo to BI 690517|DRUG: Empagliflozin|DRUG: Placebo to empagliflozin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Timely Administration of IV Magnesium Sulfate in Patients With a Moderate Asthma Exacerbation
Status: RECRUITING
Conditions: Asthma in Children|Asthma Attack
Interventions: DRUG: Magnesium Sulfate within the first hour|OTHER: No Magnesium sulfate within the first hour
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Peritoneal in Laparoscopic Ventral Hernia Repair 2
Status: COMPLETED
Conditions: Hernia, Ventral|Seroma as Procedural Complication
Interventions: PROCEDURE: Peritoneal bridging|PROCEDURE: No peritoneal bridging
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of ICSI Outcomes in Cycles Using Testicular and Ejaculate Sperm From Couples With High SDF
Status: RECRUITING
Conditions: Oligospermia|DNA Damage|IVF|ICSI|Embryo
Interventions: PROCEDURE: Testicular biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Observational Study on Infusion-related Adverse Events at Administration of MabThera (Rituximab) in Patients With Chronic Lymphocytic Leukemia
Status: COMPLETED
Conditions: Lymphocytic Leukemia, Chronic
Interventions: DRUG: rituximab [Mabthera/Rituxan]
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety of Levocetirizine 8 Weeks Prior and After the Onset of the Grass Pollen Season in Subjects With SAR
Status: COMPLETED
Conditions: Rhinitis, Allergic, Seasonal
Interventions: DRUG: Levocetirizine dihydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Effects of Two Frequencies of Application of Photobiomodulation on Facial Rejuvenation
Status: RECRUITING
Conditions: Wrinkle|Facial Expression
Interventions: RADIATION: Photobiomodulation twice a week|RADIATION: Photobiomodulation three times a week|OTHER: Simulated Photobiomodulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Antibiotic Prophylaxis for Bladder Botox
Status: RECRUITING
Conditions: Idiopathic Overactive Bladder|Postoperative Urinary Tract Infection
Interventions: DRUG: Ciprofloxacin|OTHER: Placebo Pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: (Mis)Perceptions About Healthy Eating: Effects on Food Intake and Appetite in Men and Women
Status: COMPLETED
Conditions: Eating|Obesity
Interventions: BEHAVIORAL: Healthy|BEHAVIORAL: Diet|BEHAVIORAL: Unhealthy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: A Safety and Biodistribution Study of [I-124]-CPD-1028 Injection in Solid Tumours
Status: COMPLETED
Conditions: Cancer
Interventions: DRUG: [I-124]-CPD-1028 Injection|BIOLOGICAL: CPD-1061
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety and Immunogenicity of the Candidate Vaccine MVA-MERS-S_DF-1 Against MERS
Status: ACTIVE_NOT_RECRUITING
Conditions: MERS (Middle East Respiratory Syndrome)
Interventions: BIOLOGICAL: MVA-MERS-S_DF1 - Low Dose|BIOLOGICAL: MVA-MERS-S_DF1 - High Dose|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of a Physical Rehabilitation Program Using Virtual Reality in Patients With Chronic Tendinopathy (Virtendon-Rehab)
Status: RECRUITING
Conditions: Tendinopathy|Patellar Tendinopathy|Tendinopathy, Elbow|Tendinopathy Rotator Cuff|Achilles Tendinopathy
Interventions: PROCEDURE: Virtual reality|OTHER: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of Different Formulations of Monovalent Influenza A/Astrakhan/3212/2020 Like (H5N8) Virus Vaccine With AS03 Adjuvant System in Medically Stable Adults
Status: ACTIVE_NOT_RECRUITING
Conditions: Influenza, Human
Interventions: BIOLOGICAL: FLU Q-PAN H5N8 Formulation 1|BIOLOGICAL: AS03B|BIOLOGICAL: AS03A|BIOLOGICAL: FLU Q-PAN H5N8 Formulation 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Esophageal Injuries in Corrosives in Assiut Governorate - Experimental Comparison Between Different Treatments
Status: UNKNOWN
Conditions: Clinico-epidemiological Characteristics of Corrosive Patients Presenting at Assiut Governorate
Interventions: BEHAVIORAL: development of complications or not
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Printed Education Materials in Patients Who Are Finishing Treatment for Stage I, Stage II, or Stage IIIA Breast Cancer, Colorectal Cancer, Prostate Cancer, or Chest Cancer
Status: COMPLETED
Conditions: Breast Cancer|Colorectal Cancer|Lung Cancer|Malignant Mesothelioma|Prostate Cancer|Psychosocial Effects of Cancer and Its Treatment|Thymoma and Thymic Carcinoma
Interventions: OTHER: educational intervention|PROCEDURE: psychosocial assessment and care|PROCEDURE: quality-of-life assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Comparison of Supraclavicular and Costoclavicular Brachial Plexus Blocks in Adult Patients
Status: RECRUITING
Conditions: Diaphragm Injury
Interventions: DIAGNOSTIC_TEST: Ultrasonographic measurement of diaphragm thickness
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Human Absorption, Distribution and Metabolism Study (hAME) [14C]-KD025
Status: COMPLETED
Conditions: Autoimmune Diseases|Fibrosis
Interventions: DRUG: Belumosudil 200 mg tablet|DRUG: [14C]-KD025 at a dose of 100 μg in a 5 mL solution IV microdose|DRUG: [14C]-KD025 200 mg capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Efficacy of Trimethoprim in Wound Healing of Patients With Epidermolysis Bullosa
Status: COMPLETED
Conditions: Epidermolysis Bullosa
Interventions: DRUG: Trimethoprim|DRUG: Trimethoprim
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study in the United Sates That Looks at the Safety and Effectiveness of Pradaxa Pellets in Children Aged 3 Months to Less Than 12 Years Who Need Treatment of a Blood Clot or Who Have Had a Blood Clot and Are at Risk of Developing Another Blood Clot
Status: RECRUITING
Conditions: Venous Thromboembolism
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: High Flow Nasal Oxygen Versus Usual Care in COPD Pulmonary Rehabiliation
Status: UNKNOWN
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: OTHER: Usual care|OTHER: High flow nasal oxygen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diagnostic of Transient Lower Esophageal Sphincter Relaxation With Combined Impedance and High Resolution Manometry in Patients With GERD
Status: COMPLETED
Conditions: Gastroesophageal Reflux Disease
Interventions: PROCEDURE: High resolution manometry
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Brief Title : Optimized Endoscopic Submucosal Dissection With Snaring for Colorectal Neoplasm
Status: UNKNOWN
Conditions: Colorectal Neoplasms
Interventions: PROCEDURE: Optimized ESD with snaring|PROCEDURE: Conventional ESD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Neuroprotection Impact of Cyclosporin A in Cerebral Infarction
Status: COMPLETED
Conditions: Stroke
Interventions: DRUG: Ciclosprin A|DRUG: Injectable Saline Solution.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Anticoagulant Therapy With Bivalirudin in the Performance of Percutaneous Coronary Intervention in Patients With Heparin-Induced Thrombocytopenia (AT BAT, First Inning)
Status: COMPLETED
Conditions: Heparin-Induced Thrombocytopenia|Thrombosis
Interventions: DRUG: bivalirudin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose Escalation, Safety and Pharmacokinetic Study of SAR103168 in Patients Refractory/ Relapsed Acute Leukemias or High-risk Myelodysplastic Syndromes
Status: COMPLETED
Conditions: Acute Myelogenous Leukemia
Interventions: DRUG: SAR103168
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Efficacy and Cost Analysis of the Conformable Thoracic Stent Graft With ACTIVE CONTROL
Status: RECRUITING
Conditions: Thoracic Aorta|Thoracic Aorta Aneurysm|Thoracic Aorta Abnormality
Interventions: DEVICE: thoracic endovascular repair
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Real-world Registry Investigating Sirolimus-coated Balloon Versus Paclitaxel-coated Balloon Angioplasty for the Treatment of Dysfunctional Arteriovenous Fistula
Status: UNKNOWN
Conditions: Dialysis Access Malfunction|Stenosis
Interventions: DEVICE: Sirolimus Drug Coated Balloon|DEVICE: Paclitaxel Drug Coated Balloon
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: An Observational Study of Continuous Oral Dosing of Abiraterone Acetate in Castration-Resistant Prostate Cancer Patients Evaluating Androgens and Steroid Metabolites in Bone Marrow Plasma
Status: COMPLETED
Conditions: Prostate Neoplasms
Interventions: DRUG: Abiraterone acetate|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Resolution of Sickle Cell Leg Ulcers With Voxelotor
Status: ACTIVE_NOT_RECRUITING
Conditions: Sickle Cell Disease|Leg Ulcers
Interventions: DRUG: Voxelotor Oral Tablet|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Application of Fluorescence Laparoscopy in the Treatment of Adenocarcinoma of the Esophagogastric Junction
Status: UNKNOWN
Conditions: Fluorescence Laparoscopy|Adenocarcinoma of the Esophagogastric Junction
Interventions: PROCEDURE: fluorescent laparoscopic radical gastrectomy|PROCEDURE: traditional laparoscopic radical gastrectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Morphological and Functional Retinal Changes Following Retinal Photocoagulation
Status: COMPLETED
Conditions: Proliferative Diabetic Retinopathy|Macular Edema
Interventions: PROCEDURE: laser treatment with PASCAL®|PROCEDURE: laser treatment with PASCAL®|PROCEDURE: laser treatment with PASCAL®|PROCEDURE: laser treatment with conventional laser system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: A Study of MK-5720 in Participants With Schizophrenia (MK-5720-001)
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: MK-5720|DRUG: Placebo to MK-5720|DRUG: MK-8189|DRUG: Placebo to MK-8189
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of a Physical Activity Intervention on Preventing Obesity During the Adiposity Rebound Period.
Status: UNKNOWN
Conditions: Physical Activity|Adiposity|Children|Obesity|Cardiovascular Disease
Interventions: BEHAVIORAL: MOVI-KIDS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Bladder Wall Blood Perfusion Pattern and Sexual Dysfunction in Female Patients With Lower Urinary Tract Symptoms, and the Association of That Perfusion Pattern and Therapeutic Efficacy of Antimuscarincs for Female Overactive Bladder Syndrome.
Status: COMPLETED
Conditions: Lower Urinary Tract Symptoms
Interventions: DRUG: Tolterodine SR
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intermittent Catheterization in Spinal Cord Injured Men
Status: TERMINATED
Conditions: Spinal Cord Injuries
Interventions: DEVICE: SelfCath (comparator)|DEVICE: Product A SelfCath and urine bag, Conveen Security+|DEVICE: Product B SelfCath and urine bag, Conveen Contour
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: FR901228 in Treating Patients With Recurrent High-Grade Gliomas
Status: COMPLETED
Conditions: Adult Anaplastic Astrocytoma|Adult Anaplastic Oligodendroglioma|Adult Giant Cell Glioblastoma|Adult Gliosarcoma|Recurrent Adult Brain Tumor
Interventions: DRUG: depsipeptide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of LY900020 in Healthy Chinese Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: LY900020|DRUG: Metformin XR|DRUG: Atorvastatin|DRUG: Valsartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Impact of a Digital Solution (CardiCare™) on Cardiorespiratory Fitness Improvement in Patients Discharged From a Phase 2 Cardiac Rehabilitation Following an Acute Coronary Syndrome
Status: WITHDRAWN
Conditions: Acute Coronary Syndrome
Interventions: OTHER: Wear an actigraph|OTHER: Use the mobile application CardiCare™ and wear an actigraph
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Anti-ALPP CAR-T Cells Immunotherapy for Advanced Solid Tumors
Status: RECRUITING
Conditions: Solid Tumors
Interventions: DRUG: Retroviral vector-transduced autologous T cells to express anti-ALPP CARs
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevention and Treatment With Hydroxychloroquine + Azithromycin of Acute Respiratory Syndrome Induced by COVID-19
Status: UNKNOWN
Conditions: Acute Respiratory Distress Syndrome|Covid19
Interventions: DRUG: Hydroxychloroquine Pill + Azithromycin Pill|DRUG: SOC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radiolabeled BC8 Antibody, Busulfan, Cyclophosphamide Followed by Donor Stem Cell Transplant in Treating Patients With Acute Myelogenous Leukemia in First Remission
Status: COMPLETED
Conditions: Adult Acute Myeloid Leukemia in Remission|Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities|Adult Acute Myeloid Leukemia With Del(5q)|Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)|Adult Acute Myeloid Leukemia With t(15;17)(q22;q12)|Adult Acute Myeloid Leukemia With t(16;16)(p13;q22)|Adult Acute Myeloid Leukemia With t(8;21)(q22;q22)
Interventions: RADIATION: iodine I 131 monoclonal antibody BC8|DRUG: busulfan|DRUG: cyclophosphamide|PROCEDURE: allogeneic bone marrow transplantation|PROCEDURE: allogeneic hematopoietic stem cell transplantation|PROCEDURE: peripheral blood stem cell transplantation|DRUG: cyclosporine|DRUG: methotrexate|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Piemonte Association in the Treatment of Type II Diabetes Mellitus
Status: NOT_YET_RECRUITING
Conditions: Type II Diabetes
Interventions: DRUG: PIEMONTE|OTHER: PIEMONTE PLACEBO|DRUG: EMPAGLIFLOZIN|OTHER: PLACEBO EMPAGLIFLOZIN|DRUG: PIOGLITAZONE|OTHER: PLACEBO PIOGLITAZONE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Home Rehabilitation Improves Cardiac Effort in Pulmonary Arterial Hypertension
Status: RECRUITING
Conditions: Pulmonary Arterial Hypertension PAH
Interventions: BEHAVIORAL: Exercise|BEHAVIORAL: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The iStep Study: Development and Validation of an Incremental Exercise Step Test for Children With Cystic Fibrosis
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: OTHER: iStep exercise test|OTHER: CPET exercise test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Implementing Evidence in the Detection and Treatment of Post Stroke Depression
Status: COMPLETED
Conditions: Mental Health|Neurology|Health Services
Interventions: BEHAVIORAL: self management of PSD symptoms|PROCEDURE: screening and treatment of PSD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Measuring Changes in Body Composition and Physical Function in Patients With Childhood Cancers
Status: RECRUITING
Conditions: Cancer|Malignant Neoplasm
Interventions: OTHER: Bioelectrical impedance Analysis (BIA)|OTHER: D3-Creatine Dilution (D3Cr)|OTHER: 6-Minute Walk Test (6MWT)|OTHER: Timed Up and Go (TUG)|OTHER: 30-second Sit-to-Stand (STS)|OTHER: Hand Grip Strength (GS)|OTHER: PBTL p16 expression|OTHER: CT, MR and PET Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Immunogenicity and Safety Study of the 13-valent Pneumococcal Polysaccharide Conjugate Vaccine in 2-71 Months Old Healthy Infants and Toddlers (the Youngest Could be 6 Weeks Old)
Status: COMPLETED
Conditions: Diseases Caused by Streptococcus Pneumoniae Serotypes
Interventions: BIOLOGICAL: 7-valent pneumococcal conjugate vaccine|BIOLOGICAL: 13-valent pneumococcal polysaccharide conjugate vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Immunogenicity of a Commercially Available Influenza Vaccine (Formulation 2006/2007) When Administered to Subjects 18 Years of Age or Older
Status: WITHDRAWN
Conditions: Influenza
Interventions: BIOLOGICAL: influenza surface antigen inactivated vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Different Feeding Method on Gastrointestinal Function of Septic Patients (DFM-GF Trial)
Status: WITHDRAWN
Conditions: Sepsis|Intestinal Dysfunction
Interventions: DEVICE: 24-hours group|DEVICE: 16-hours group|DEVICE: intermittent group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Optimizing Care for Children Hospitalized With Community-acquired Pneumonia: Short-course Therapy
Status: RECRUITING
Conditions: Community-acquired Pneumonia
Interventions: DRUG: Placebo|DRUG: Amoxicillin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Blood Products Transfusion in Cardiac Surgery After the Implementation of a Coagulation Monitoring System at Patient Bedside: Thromboelastometry Versus Standard Transfusion Protocol
Status: TERMINATED
Conditions: Hemostatic Disorders
Interventions: PROCEDURE: Group ROTEM|OTHER: Group C
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Comparison of Coronally Advanced Lingual Flap to Modified MPI for Flap Advancement in Partially Edentulous Patients
Status: UNKNOWN
Conditions: Alveolar Bone Loss
Interventions: PROCEDURE: The coronally advanced lingual flap|PROCEDURE: Modified periosteal releasing Incision
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Subjective and Objective Outcome of Septoplasty With or Without Infundibulotomy
Status: RECRUITING
Conditions: Nasal Blockage|Nasal Obstruction|Septum; Deviation
Interventions: PROCEDURE: Infundibultomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Beclomethasone Dipropionate Nasal Aerosol for Perennial Allergic Rhinitis
Status: COMPLETED
Conditions: Perennial Allergic Rhinitis (PAR)
Interventions: DRUG: Beclomethasone Dipropionate (BDP) Nasal Aerosol
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Paracetamol Discontinuation in the Elderly After Long-term Consumption
Status: UNKNOWN
Conditions: Pain, Chronic|Pain, Medication|Pain, Discontinuation
Interventions: DRUG: Placebo|DRUG: Paracetamol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: 2-arm Trial of Paclitaxel Plus Bevacizumab vs. Capecitabine Plus Bevacizumab
Status: COMPLETED
Conditions: Metastatic Breast Cancer
Interventions: BIOLOGICAL: Bevacizumab and Paclitaxel|BIOLOGICAL: Bevacizumab and Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dexamethasone Infusion in Community-acquired Pneumonia
Status: COMPLETED
Conditions: Pneumonia
Interventions: DRUG: dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Exercise Given to Cashiers Along With Ergonomics Training on Pain and Work Performance
Status: COMPLETED
Conditions: Work-related Illness|Work Related Upper Limb Disorder
Interventions: OTHER: control|OTHER: exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Safety and Tolerability of PDR001 in Combination With Sorafenib and to Identify the Maximum Tolerated Dose and/or Phase 2 Dose for This Combination in Advanced Hepatocellular Patients
Status: COMPLETED
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: PDR001|DRUG: Sorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EMD 525797 in Subjects With Asymptomatic or Mildly Symptomatic Metastatic Castrate-resistant Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer Metastatic
Interventions: DRUG: EMD 525797|DRUG: EMD 525797|OTHER: Placebo|OTHER: Standard of Care (SoC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 600 mg Amoxicillin/42.9 mg Clavulanate Postassium /5 mL Suspension Under Fed Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: 600 mg Amoxicillin/42.9 mg Clavulanate Postassium /5 mL|DRUG: Augmentin ES-600™
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Evaluation of the Effectiveness of the Local Application of Lemon in the Prevention of Blisters in Ultra-trail Runners
Status: UNKNOWN
Conditions: Blister of Foot|Sport Injury
Interventions: OTHER: Lemon foot to prevent blister
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Temsirolimus Therapy on Circulating Tumor Cell Biology In Men With Castration Resistant Metastatic Prostate Cancer
Status: TERMINATED
Conditions: Prostate Cancer
Interventions: DRUG: Temsirolimus|DRUG: Diphenhydramine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Interaction of Melatonin and MTNR1B Genotype on Glucose Control - Study 1
Status: COMPLETED
Conditions: Glucose|Circadian Rhythm|Melatonin|Genes
Interventions: DIETARY_SUPPLEMENT: melatonin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Fentanyl Sublingual Spray in Opioid Naive Participants
Status: COMPLETED
Conditions: Pharmacology
Interventions: DRUG: Fentanyl Sublingual Spray|DRUG: Fentanyl Citrate IV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effects of Emollient Therapy on the Skin Barrier
Status: COMPLETED
Conditions: Atopic Dermatitis|Eczema
Interventions: OTHER: Pediatric Moisturizer|OTHER: Adult Moisturizer
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The MANTRA Trial (MANdibular TRauma and Antibiotic Use)
Status: NOT_YET_RECRUITING
Conditions: Mandible Fracture|Post-operative Antibiotics
Interventions: DRUG: Different post-operative antibiotic regimens following surgical treatment of mandible fractures
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Liposome Encapsulated SN38 (LE-SN38) in Patients With Advanced Cancer
Status: COMPLETED
Conditions: Neoplasms
Interventions: DRUG: Liposome-encapsulated SN38
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vitamin B Complex and Diabetic Nephropathy in Type 1 Diabetes
Status: COMPLETED
Conditions: Plasma Homocysteine|HbA1c Level
Interventions: DRUG: Vitamin B complex tablets (Neurorubine TM -Forte Lactab TM)|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT