pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Surgical Trial to Evaluate the Impact of a Lymphoscintigraphy Prior to Sentinel Node Biopsy in Early Breast Cancer
Status: COMPLETED
Conditions: Early-Stage Breast Carcinoma
Interventions: PROCEDURE: without preoperative access to lymphoscintigraphy findings
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: PIPAC for the Treatment of Colorectal Peritoneal Metastases
Status: RECRUITING
Conditions: Colorectal Neoplasms|Peritoneal Metastases
Interventions: PROCEDURE: Pressurised Intraperitoneal Aerosol Chemotherapy (PIPAC)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ph2 Study of Savolitinib and Durvalumab (MEDI4736) Combination in Advanced MET Amplified Gastric Cancer(VIKTORY-2)
Status: RECRUITING
Conditions: Stomach Cancer, Adenocarcinoma
Interventions: DRUG: Durvalumab|DRUG: Savolitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Xiaflex: Trial of Effectivenss iN Dupuytren's
Status: COMPLETED
Conditions: Dupuytren's Disease
Interventions: DRUG: collagenase injection|PROCEDURE: limited palmar fasciectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ketamine or Neostigmine for Serratus Anterior Plane Block in Modified Radical Mastectomy
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: PROCEDURE: Serratus Anterior Plane Block Technique|PROCEDURE: General anesthesia|DRUG: bupivacaine +ketamine|DRUG: bupivacaine + neostigmine|DRUG: bupivacaine +saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Reducing Sedentary Behavior to Improve Sleep: an Ancillary Study to the RESET BP Clinical Trial
Status: COMPLETED
Conditions: Sleep|Obstructive Sleep Apnea|Insomnia
Interventions: BEHAVIORAL: Behavioral Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: High-Flow Nasal Oxygen Therapy for Exacerbation of Chronic Pulmonary Obstructive Disease.
Status: RECRUITING
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: OTHER: Noninvasive ventilation|OTHER: High-Flow Nasal Oxygen therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Evaluate the Efficacy and Safety of Capecitabine Prior to Surgery in Women With Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: 5-Fluorouracil|DRUG: Capecitabine|DRUG: Cyclophosphamide|DRUG: Docetaxel|DRUG: Epirubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of Pneumococcal Conjugate Formulations in Healthy Adults 18 Through 49 Years of Age
Status: COMPLETED
Conditions: Pneumococcal Disease
Interventions: OTHER: Candidate-1|OTHER: Candidate-2|OTHER: Candidate-3|OTHER: Candidate-4|OTHER: Candidate-5|OTHER: Candidate-6|OTHER: Candidate Control|BIOLOGICAL: 13vPnC|BIOLOGICAL: PCV15
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Angelica Gigas Dietary Supplements and Human Immune Cells
Status: ACTIVE_NOT_RECRUITING
Conditions: Innate Immune Cells
Interventions: DIETARY_SUPPLEMENT: Cogni.Q|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Gait Pattern Analysis and Feasibility of Gait Training With a Walking Assist Robot in Stroke Patients and Elderly Adults
Status: COMPLETED
Conditions: Stroke|Healthy
Interventions: DEVICE: gait rehabilitation with Samsung Hip Assist v1|OTHER: gait rehabilitation without Samsung Hip Assist v1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Platform Assessing Regimens and Durations In a Global Multisite Consortium for TB
Status: RECRUITING
Conditions: Pulmonary Tuberculosis
Interventions: DRUG: GSK3036656|DRUG: BTZ-043|DRUG: Bedaquiline (B)|DRUG: Delamanid (D)|DRUG: Pretomanid (Pa)|DRUG: Moxifloxacin (M)|DRUG: Linezolid (L)|DRUG: Pyrazinamide (Z)|DRUG: Rifampicin (R)|DRUG: Isoniazid (H)|DRUG: Ethambutol (E)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fear-focused Self-Compassion Therapy for Young Breast Cancer Patients' Fear of Cancer Recurrence
Status: RECRUITING
Conditions: Fear of Cancer Recurrence
Interventions: BEHAVIORAL: Fear-focused Self-Compassion Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Improving Treatment Outcomes in Pharmacotherapy of Generalized Social Anxiety Disorder
Status: COMPLETED
Conditions: Social Phobia
Interventions: DRUG: Sertraline|DRUG: Venlafaxine|DRUG: Placebo|DRUG: Clonazepam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Upper Airway Stimulation in Patients With Obstructive Sleep Apnea
Status: COMPLETED
Conditions: Obstructive Sleep Apnea
Interventions: DEVICE: Upper Airway Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparison of PF708 and Forteo in Osteoporosis Patients
Status: COMPLETED
Conditions: Osteoporosis
Interventions: DRUG: Teriparatide (PF708)|DRUG: Teriparatide (Forteo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Intravenous Immunoglobulin in Amnestic Mild Cognitive Impairment
Status: COMPLETED
Conditions: Mild Cognitive Impairment
Interventions: DRUG: NewGam 10% IVIG|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ultrasound-Guided Transversus Abdominis Plan (TAP) Block in Endovascular Cardiac Interventions
Status: NOT_YET_RECRUITING
Conditions: Anesthesiology|Percutaneous Coronary Intervention|Cardiac Catheterization|Analgesia|Satisfaction, Patient
Interventions: DEVICE: ultrasound|PROCEDURE: parenteral local anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Validity of Urinary Titin and Skeletal Muscle Index as Predictor of Muscle Weakness in Critically Ill Patients. A Prospective Cohort Study
Status: ENROLLING_BY_INVITATION
Conditions: Urinary Titin
Interventions: DIAGNOSTIC_TEST: Urinary titin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phase 2/3 Study Evaluating the Safety and Efficacy of PTX-022 in Treatment of Adults With Pachyonychia Congenita
Status: COMPLETED
Conditions: Pachyonychia Congenita
Interventions: DRUG: PTX-022|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study to Assess Number of Patients for Main Trial
Status: COMPLETED
Conditions: Wound Healing
Interventions: DRUG: Dexpanthenol (Bepanthen® Wund- und Heilsalbe, BAY81-2996)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Restoring Glycocalyx Thickness in Older Adults to Improve Vascular Function
Status: COMPLETED
Conditions: Aging|Vascular Stiffness|Endothelial Dysfunction
Interventions: DIETARY_SUPPLEMENT: Endocalyx Pro (Microvascular Health Solutions, US Patent Number: 9943572)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of Locomotor Therapy Using Robot-Driven Gait Orthosis System in Multiple Sclerosis Patients
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DEVICE: robot-assisted gait training (RAGT)|DEVICE: conventional walking training (CWT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nitrous Oxide for Analgesia During Nasogastric Tube Placement in Young Children
Status: RECRUITING
Conditions: Mild to Moderate Dehydration
Interventions: DRUG: Nitrous Oxide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Role of Matrix Metalloproteinase 2 and 9 Enzymes in Developing Chronic Thromboembolic Pulmonary Hypertension
Status: COMPLETED
Conditions: Chronic Thromboembolic Pulmonary Hypertension
Interventions: OTHER: matrix metalloproteinase enzymes 2 and 9
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Bendamustine and Radiation Therapy in Treating Patients With Brain Metastases Caused by Solid Tumors
Status: COMPLETED
Conditions: Metastatic Cancer|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: bendamustine|OTHER: laboratory biomarker analysis|PROCEDURE: Surgical Resection of Brain Metastases|RADIATION: Stereotactic body radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Carotid Endarterectomy Versus Carotid Artery Stenting? A Prospective Comparison of Neuropsychological Outcome in Patients With Carotid Stenosis.
Status: COMPLETED
Conditions: Carotid Stenosis
Interventions: PROCEDURE: Carotid endarterectomy (CEA)|PROCEDURE: Carotid stenting (CAS)|PROCEDURE: Neurocognitive functions|PROCEDURE: Levels of biomarkers|PROCEDURE: Detection of peri-operative embolization|PROCEDURE: Validation results
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Stop of Proton-pump Inhibitor Treatment in Patients With Liver Cirrhosis - a Double-blind, Placebo-controlled Trial
Status: RECRUITING
Conditions: Liver Cirrhosis
Interventions: DRUG: Placebo|DRUG: Esomeprazole 20mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Testing the Combination of the Anti-cancer Drugs Copanlisib, Olaparib, and MEDI4736 (Durvalumab) in Patients With Advanced Solid Tumors With Selected Mutations
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Malignant Solid Neoplasm|Metastatic Malignant Solid Neoplasm|Unresectable Malignant Solid Neoplasm
Interventions: PROCEDURE: Biopsy|PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|DRUG: Copanlisib Hydrochloride|BIOLOGICAL: Durvalumab|PROCEDURE: Echocardiography|PROCEDURE: Magnetic Resonance Imaging|DRUG: Olaparib|PROCEDURE: X-Ray Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Does Perioperative Pregabalin Reduce Postoperative Pain After Arthroscopic Anterior Cruciate Ligament Reconstruction Surgery Under Spinal Anesthesia?
Status: COMPLETED
Conditions: Anterior Cruciate Ligament (ACL) Reconstruction
Interventions: DRUG: pregabalin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Multicenter Study of HGT-1110 Administered Intrathecally in Children With Metachromatic Leukodystrophy (MLD)
Status: COMPLETED
Conditions: Metachromatic Leukodystrophy (MLD)
Interventions: BIOLOGICAL: Recombinant human arylsulfatase A
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Flucinolone Acetonide Implant for Treating Refractory Ocular Behcet's Disease
Status: UNKNOWN
Conditions: Ocular Behcet's Disease,|Non-Infectious Uveitis|Refractory Uveitis
Interventions: DRUG: flucinolone acetonide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Depth of Anesthesia With 4-Channel EEG in Patients Undergoing Drug-Induced Sleep Endoscopy (DISE)
Status: ACTIVE_NOT_RECRUITING
Conditions: Seeing the Benefits of Using 4 Channel EEG During the DISE Procedure With Sedation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Influence of a Stabilization Splint on the Body Posture
Status: COMPLETED
Conditions: Temporomandibular Disorders|Craniomandibular Disorders|Arthromyalgia|Chronic Disease|Occlusal Appliance
Interventions: DEVICE: occlusal appliance
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Use of Hyaluronic Acid Gel To Prevent Intrauterine Adhesions In Hysteroscopic Surgery
Status: UNKNOWN
Conditions: Tissue Adhesions
Interventions: DRUG: Hyaluronan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Assessment of Plasma and NGAL for the Early Prediction of Acute Kidney Injury After Cardiac Surgery in Adults Study
Status: COMPLETED
Conditions: Acute Kidney Injury (AKI)|Chronic Kidney Disease (CKD)|End Stage Renal Disease (ESRD)|Estimated Glomerular Filtration Rate (eGFR)|Neutrophil Gelatinase-associated Lipocalin (NGAL)|Serum Creatinine (SCr)|Urine Creatinine (UCr)|Urine Albumin (UAlb)
Interventions: PROCEDURE: CPB Surgery
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Chronic Subdural Hematoma - Reduction of Recurrence by Treatment With Angiotensin Converting Enzyme Inhibitors
Status: TERMINATED
Conditions: Hematoma, Subdural, Chronic
Interventions: DRUG: Perindopril|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Significance of Assesment of Serum miRNA-30a in Childhood Nephrotic Syndrome
Status: UNKNOWN
Conditions: Nephrotic Syndrome Steroid-Resistant
Interventions: DIAGNOSTIC_TEST: ‗Urine analysis ‗Urine protein quantification ‗Serum albumin ‗Lipid profile.Quantitation of miRNA -30a by Real-time polymerase chain reaction (Q-PCR) in peripheral blood.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: EF5 in Assessing Tumor Response to Anticancer Therapy in Patients With Stage I, Stage II, or Stage III Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DRUG: EF5|OTHER: flow cytometry|OTHER: immunohistochemistry staining method
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: DIAGNOSTIC
Clinical trial: Comparison of Laparoscopic Surgery Versus Open Surgery in the Treatment of Adhesive Small Bowel Obstruction
Status: UNKNOWN
Conditions: Adhesive Small Bowel Obstruction
Interventions: PROCEDURE: Laparoscopic adhesiolysis|PROCEDURE: Open adhesiolysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vorinostat in Treating Patients With Relapsed or Refractory Advanced Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Adult Favorable Prognosis Hodgkin Lymphoma|Adult Lymphocyte Depletion Hodgkin Lymphoma|Adult Lymphocyte Predominant Hodgkin Lymphoma|Adult Mixed Cellularity Hodgkin Lymphoma|Adult Nodular Lymphocyte Predominant Hodgkin Lymphoma|Adult Nodular Sclerosis Hodgkin Lymphoma|Adult Unfavorable Prognosis Hodgkin Lymphoma|Recurrent Adult Hodgkin Lymphoma
Interventions: DRUG: vorinostat|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I Study to Investigate the Tolerability and Safety of ONO-4685 Given as Monotherapy in T Cell Lymphoma and CLL/SLL
Status: RECRUITING
Conditions: Relapsed or Refractory T Cell Lymphoma and Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma
Interventions: DRUG: ONO-4685
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Reduction of Dust Mite Allergenic Load on Step Down of Inhaled Corticosteroids in Stable Asthma
Status: TERMINATED
Conditions: Asthma
Interventions: DEVICE: Acar'up system|DEVICE: Acar'up placebo system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: TAP Block and Subacute Pain in Inguinal Herniography
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: PROCEDURE: transversus abdominis plane block|DRUG: Tramadol and paracetamol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Inter Disciplinary Approach to Vocabulary Development in Hearing Impairment
Status: UNKNOWN
Conditions: Hearing Impaired Children
Interventions: OTHER: Vocabulary based intervention- Non Collaborative|OTHER: Vocabulary based intervention - Collaborative
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of CG200745 PPA in Combination With Gemcitabine and Erlotinib for Advanced Pancreatic Cancer
Status: UNKNOWN
Conditions: Pancreatic Neoplasms
Interventions: DRUG: CG200745 PPA|DRUG: Gemcitabine|DRUG: Erlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adductor Canal Block With Continuous Infusion Versus Intermittent Boluses and Morphine Consumption
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: ropivacaine 0.2%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A New Technique for Sacrospinous-Sacrotuberous Fixation for the Treatment of Uterovaginal and Vaginal Vault Prolapse
Status: COMPLETED
Conditions: Uterovaginal and Vaginal Vault Prolapse
Interventions: PROCEDURE: Sacrospinous-Sacrotuberous fixation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exposure Therapy vs. Standardized Education for Distress Related to Somatic Symptoms
Status: ACTIVE_NOT_RECRUITING
Conditions: Somatic Symptom and Related Disorders|Medically Unexplained Symptoms|Psychological Factors Affecting Other Medical Conditions
Interventions: BEHAVIORAL: Exposure|BEHAVIORAL: Standardized education|BEHAVIORAL: Prolonged assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating The Efficacy And Safety Of Donepezil Hydrochloride (HCl) (Aricept) In Treating Cognitive Dysfunction Exhibited By Children With Down Syndrome
Status: COMPLETED
Conditions: Down Syndrome
Interventions: DRUG: Donepezil HCl|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness and Efficacy of the Combination of the Integrated Psychological Therapy and Metacognitive Training.
Status: COMPLETED
Conditions: Schizophrenia
Interventions: COMBINATION_PRODUCT: The combination of the Integrated Psychological Therapy and Metacognitive Training in individuals with schizophrenia and treatment resistant schizophrenia
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intravenous CG7870 in Combination With Docetaxel in Patients With Metastatic Hormone-Refractory Prostate Cancer
Status: TERMINATED
Conditions: Prostate Cancer
Interventions: BIOLOGICAL: CG7870
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of HA121-28 Tablets in Patients With Medullary Thyroid Carcinoma (MTC)
Status: RECRUITING
Conditions: Medullary Thyroid Carcinoma
Interventions: DRUG: HA121-28 tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intraoperative S-ketamine to Prevent Postoperative Hyperalgesia in Patients Undergoing Video-assisted Thoracic Surgery
Status: UNKNOWN
Conditions: Postoperative Hyperalgesia
Interventions: DRUG: S-ketamine|DRUG: saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of AQX-1125 in Unstable COPD
Status: COMPLETED
Conditions: COPD
Interventions: DRUG: AQX-1125|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Esophagogastric Junction Distensibility During Hiatal Hernia Repair
Status: RECRUITING
Conditions: Esophagogastric Junction Distensibility|Hiatal Hernia
Interventions: PROCEDURE: Surgeon unblinded|DEVICE: EndoFLIP 1.0 System EF-100
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Atezolizumab Plus 8 Gy Single-fraction Radiotherapy for Advanced Oligoprogressive NSCLC
Status: ACTIVE_NOT_RECRUITING
Conditions: NSCLC Stage IV
Interventions: DRUG: Atezolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of an Injectable Fluocinolone Acetonide Intravitreal Insert (FAI)
Status: TERMINATED
Conditions: Uveitis|Uveitis, Posterior|Uveitis, Intermediate
Interventions: DRUG: Sham Injector|DRUG: FAI Insert
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Pharmacokinetics, Safety and Tolerability of Nebulized Ensifentrine in Healthy Chinese Subjects
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Ensifentrine|DRUG: Ensifentrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Double Tract Anastomosis and Gastric Tube Anastomosis to Proximal Gastrectomy
Status: TERMINATED
Conditions: Complications|Quality of Life|Remnant Gastritis|Reflux Esophagitis
Interventions: PROCEDURE: Gastric tube anastomosis|PROCEDURE: Double-track anastomosis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Standard Systemic Therapy Combined With High/Low-dose Radiotherapy Plus Toripalimab for Metastatic Colorectal Cancer
Status: RECRUITING
Conditions: Microsatellite Stable Metastatic Colorectal Cancer
Interventions: DRUG: standard systemic therapy combined with high/low-dose radiotherapy plus toripalimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clofarabine Combinations in Relapsed/Refractory Acute Myeloid Leukemia (AML), Myelodysplastic Syndromes (MDS) and Myeloid Blast Phase Chronic Myeloid Leukemia (CML)
Status: COMPLETED
Conditions: Acute Myeloid Leukemia|Myelodysplastic Syndrome|Chronic Myeloid Leukemia
Interventions: DRUG: Clofarabine 40mg/m^2|DRUG: Idarubicin 10mg/m^2|DRUG: Ara-C 0.75 g/m^2|DRUG: Clofarabine 22.5mg/m^2|DRUG: Ara-C 1 g/m^2|DRUG: Idarubicin 6 mg/m^2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Safety and Tolerability of AZD1390 Given With Radiation Therapy in Patients With Brain Cancer
Status: RECRUITING
Conditions: Recurrent Glioblastoma Multiforme|Primary Glioblastoma Multiforme|Brain Neoplasms, Malignant|Leptomeningeal Disease (LMD)
Interventions: RADIATION: Radiation Therapy|DRUG: AZD1390
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RF-assisted Splenic Preservation VS Conventional Treatment of Blunt Splenic Injury.
Status: COMPLETED
Conditions: Radiofrequency Can be Used to Treat Splenic Trauma Because of Its Excellent Coagulation Hemostasis
Interventions: PROCEDURE: radiofrequency ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Saccharomyces Boulardii Combined With Standard Quadruple Therapy for Eradication of Helicobacter Pylori
Status: COMPLETED
Conditions: Helicobacter Pylori Infection
Interventions: DRUG: Saccharomyces boulardii|DRUG: Esomeprazole|DRUG: Amoxicillin|DRUG: Clarithromycin|DRUG: Bismuth potassium citrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I Trial of AVN944, an IMPDH Inhibitor, in Adults With Advanced Stage Solid Tumors
Status: WITHDRAWN
Conditions: Refractory Solid Tumors
Interventions: DRUG: AVN944
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clot Dissolving Treatment for Blood Clots in the Lungs
Status: TERMINATED
Conditions: Pulmonary Embolism
Interventions: DRUG: Tenecteplase + Enoxaparin|DRUG: 0.9% Saline + Enoxaparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Unresecable and/or Metastatic Merkel Cell Carcinoma by Somatostatine Analogues
Status: COMPLETED
Conditions: Carcinoma, Merkel Cell
Interventions: DRUG: Lanreotide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Atorvastatin Treatment of Cavernous Angiomas With Symptomatic Hemorrhage Exploratory Proof of Concept (AT CASH EPOC) Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Cerebral Cavernous Malformation
Interventions: DRUG: Atorvastatin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Neoadjuvant Chemotherapy With Nanoparticle Albumin Bound Paclitaxel, Doxorubicin and Cyclophosphamide (NAC) in Patients With Stages II-III Breast Cancer
Status: TERMINATED
Conditions: Stages II-III Breast Cancer
Interventions: DRUG: Nanoparticle Albumin Bound Paclitaxel|DRUG: doxorubicin|DRUG: cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cognitive Behavioral Treatments for Post-traumatic Stress Disorder (PTSD) Sleep Disturbance
Status: COMPLETED
Conditions: Post-traumatic Stress Disorder
Interventions: BEHAVIORAL: Imagery Rehearsal|BEHAVIORAL: Sleep and Nightmare Management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pirfenidone Compared to Placebo in Post-COVID19 Pulmonary Fibrosis COVID-19
Status: UNKNOWN
Conditions: Fibrotic Pulmonary Sequelae Post-COVID19 Infection
Interventions: DRUG: Pirfenidone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Neuromuscular Electrical Stimulation (NMES) for Improving Outcomes Following Total Knee Arthroplasty (TKA)
Status: COMPLETED
Conditions: Arthropathy of Knee Joint
Interventions: DEVICE: CyMedica Orthopedics QB1 e-vive™ system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Ramelteon in Subjects With Mild to Moderate Alzheimer's Disease
Status: COMPLETED
Conditions: Chronic Insomnia
Interventions: DRUG: Ramelteon|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Plasma SCFAs After Fermentable Cereal Fibres - A Postprandial Study
Status: COMPLETED
Conditions: Overweight and Obesity
Interventions: OTHER: Breakfast Control Meal|OTHER: Breakfast Test Meal|OTHER: Breakfast Test Meal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluate Safety and Pharmacokinetics of INF904 in Subjects With Moderate to Severe Chronic Spontaneous Urticaria or Hidradenitis Suppurativa
Status: NOT_YET_RECRUITING
Conditions: Chronic Urticaria, Idiopathic|Hidradenitis|Hidradenitis Suppurativa
Interventions: DRUG: CSU lower dose treatment|DRUG: CSU high dose treatment|DRUG: CSU non responders IgE - high dose treatment|DRUG: HS low dose treatment|DRUG: HS medium dose treatment|DRUG: HS high dose treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combined Randomised and Observational Study of Surgery for Type B Ankle Fracture Treatment
Status: UNKNOWN
Conditions: Ankle Fractures
Interventions: PROCEDURE: Non Operative|PROCEDURE: Open reduction internal fixation of the ankl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Abatacept in Immune Checkpoint Inhibitor Myocarditis
Status: RECRUITING
Conditions: Myocarditis Acute|Cancer
Interventions: DRUG: Abatacept plus|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing Two Devices of Uterine Manipulation and Vaginal Fornix Delineation at Total Laparoscopic Hysterectomy
Status: COMPLETED
Conditions: Laparoscopic Hysterectomy for Benign Conditions
Interventions: DEVICE: Use of the Colpo-Probe™ Vaginal Fornix Delineator or Hohl manipulator® during total laparoscopic hysterectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of the Probiotic ES1 and Its Inactivated Form (HT-ES1) Over Symptomatology Asociated With Allergic Rhinitis
Status: RECRUITING
Conditions: Allergic Rhinitis
Interventions: DIETARY_SUPPLEMENT: ES1 group|DIETARY_SUPPLEMENT: HT-ES1 group|DIETARY_SUPPLEMENT: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dose-Finding Study of REN-1654 in Patients With Post-Herpetic Neuralgia
Status: UNKNOWN
Conditions: Neuralgia|Shingles|Peripheral Nervous System Disease
Interventions: DRUG: REN-1654
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Interaction Between Body Posture and Nocturnal Sleeping Disorders in Dysgnathic Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Dentofacial Deformities|Sleep Disorder|Posture
Interventions: OTHER: polysomnography
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect of Asthma Flare-up Clinic After Exacerbation
Status: ENROLLING_BY_INVITATION
Conditions: Asthma|Asthma Attack
Interventions: OTHER: Follow-up in a flare-up clinic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of Preoperative Chemotherapy for Early Triple Negative or HER2-positive Operable Breast Cancer
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: DRUG: Neoadjuvant Chemotherapy|DRUG: postoperative chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Shock-wave Therapy on the Resorption and Bone Formation in Maxillary Postextraction Sockets
Status: WITHDRAWN
Conditions: Loss of Teeth Due to Extraction|Bone Resorption
Interventions: DEVICE: Shockwave therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SITS (Safe Implementation of Treatments in Stroke) Open Artery by Thrombectomy in Acute Occlusive Stroke Study
Status: COMPLETED
Conditions: Ischemic Stroke
Interventions: DEVICE: Stent retriever endovascular device for thrombectomy|DRUG: Intravenous thrombolysis by alteplase (Actilyse) (optional)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Functional Lung Avoidance SPECT-guided Radiation Therapy of Lung Cancer
Status: RECRUITING
Conditions: Lung Cancer|Radiation-Induced Disorder|Radiation Pneumonitis|Pulmonary Disease|Lung Function Decreased
Interventions: DIAGNOSTIC_TEST: Single-photon-emission CT scan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MEOPA to Improve Physical Therapy Results After Multilevel Surgery
Status: COMPLETED
Conditions: Cerebral Palsy|Spastic Diplegia|Quadriplegia|Hemiplegia
Interventions: DRUG: MEOPA|DRUG: Medicinal air
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Multiple-dose Kukoamine B Mesilate in Sepsis Patients
Status: COMPLETED
Conditions: Sepsis
Interventions: DRUG: 0.06mg/kg,KB|DRUG: 0.12mg/kg,KB|DRUG: 0.24mg/,KB|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Parathyroid Hormone (PTH) and Weight-Bearing on Bone in Spinal Cord Injury (SCI)
Status: COMPLETED
Conditions: Osteoporosis|Bone Loss|Spinal Cord Injury
Interventions: DRUG: teriparatide|OTHER: weight-bearing
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Confirmation of Accuracy of the Tool-in-lesion Technology (TiLT) of the Galaxy System With Integrated TOMO Technology
Status: RECRUITING
Conditions: Lung Cancer|Nodes, Lung
Interventions: DEVICE: Robotic assisted bronchoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Vitamin D Status in Males in Jerusalem Area and Its Correlation to Parathyroid Hormone (PTH) Level and Bone Mineral Density
Status: COMPLETED
Conditions: Vitamin D Deficiency|Secondary Hyperparathyroidism|Osteomalacia
Interventions: DRUG: 25 OH vitamin D
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Safety, Tolerability and Efficacy of CYP-006TK in Adults With Diabetic Foot Ulcers
Status: ACTIVE_NOT_RECRUITING
Conditions: Diabetic Foot Ulcer|Cutaneous Ulcer
Interventions: COMBINATION_PRODUCT: CYP-006TK
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Healing of Soft Tissue Augmentation by Acellular Dermal Matrix and Autogenous Subepithelial Connective Tissue Graft
Status: WITHDRAWN
Conditions: Gingival Recession, Generalized|Graft Reaction
Interventions: PROCEDURE: Gingival Punch Biopsy after healing of Gingival Soft Tissue Augmentation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dose-response, Safety and Efficacy of Oral Semaglutide Versus Placebo and Versus Liraglutide, All as Monotherapy in Japanese Subjects With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: Semaglutide|DRUG: Placebo|DRUG: Liraglutide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Efficacy and Safety of 2 Oral Doses of Rimonabant, 5 mg/Day or 20 mg/Day, Versus Placebo, as an Aid to Smoking Cessation (STRATUS US)
Status: COMPLETED
Conditions: Smoking Cessation
Interventions: DRUG: Rimonabant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Novel PET Radioligands as Inflammatory Biomarkers in Rheumatoid Arthritis and Myositis
Status: RECRUITING
Conditions: Myositis|Inflammatory|Rheumatoid Arthritis|Healthy Volunteers
Interventions: DIAGNOSTIC_TEST: 11C-MC1|DRUG: Celecoxib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effectiveness of Intraoperative Exparel for Postoperative Pain Control in Total Knee Arthroplasty
Status: UNKNOWN
Conditions: Osteoarthritis|Total Knee Arthroplasty|Pain Management
Interventions: DRUG: Pain Cocktail with Exparel|DRUG: Pain Cocktail with Ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 4 Study to Evaluate Efficacy and Safety of Entelon Tab.150mg in Patients With Chronic Venous Disease(CVD)
Status: UNKNOWN
Conditions: Chronic Venous Disease
Interventions: DRUG: Entelon Tab.150mg|DRUG: Venitol Tab.|DRUG: Placebo of Venitol Tab.|DRUG: Placebo of Entelon Tab.150mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Psychometric Properties and Cross-cultural Adaptation of the Turkish Version of Physcian Attitudes Toward Cardiac Rehabilitation and Referral Scale-Revised (PACRR-R)
Status: RECRUITING
Conditions: Physician's Role
Interventions: OTHER: Physcian Attitudes toward Cardiac Rehabilitation and Referral Scale-Revised (PACRR-R)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study to Evaluate Safety and Tolerability of sc Immunotherapy With DM-101 in Adults With Birch Pollen Allergy
Status: COMPLETED
Conditions: Birch Pollen Allergy
Interventions: BIOLOGICAL: DM-101|BIOLOGICAL: Placebo to match DM-101
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: A Study of Decitabine (DACOGEN) in Sequential Administration With Cytarabine in Children With Relapsed or Refractory Acute Myeloid Leukemia
Status: TERMINATED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Phase1 and Phase 2: decitabine|DRUG: Phase 1: cytarabine|DRUG: Phase 2: cytarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of UC-MSCs for COVID-19 Patients
Status: COMPLETED
Conditions: Corona Virus Infection|ARDS|ARDS, Human|Acute Respiratory Distress Syndrome|COVID-19
Interventions: BIOLOGICAL: Umbilical Cord Mesenchymal Stem Cells + Heparin along with best supportive care.|OTHER: Vehicle + Heparin along with best supportive care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study on Food Influence and Drug-drug Interaction of HLX208 Tablets in Chinese Healthy Subjects
Status: COMPLETED
Conditions: NSCLC
Interventions: DRUG: HLX208|DRUG: HLX208|DRUG: HLX208|DRUG: HLX208|DRUG: Itraconazole 200 mg|DRUG: Rifampicin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Serratus Plane Block for Postoperative Pain Control
Status: TERMINATED
Conditions: Outpatient Breast Surgery|Mastopexy|Augmentation|Revision
Interventions: DRUG: Bupivicaine HCl|DRUG: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assess Efficacy and Safety of Durvalumab Alone or Combined With Bevacizumab in High Risk of Recurrence HCC Patients After Curative Treatment
Status: ACTIVE_NOT_RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Durvalumab|DRUG: Bevacizumab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Extending the Time for Thrombolysis in Emergency Neurological Deficits
Status: COMPLETED
Conditions: Stroke
Interventions: DRUG: Tissue Plasminogen Activator (Alteplase)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Tendon-to-Bone Healing Potential in Arthroscopic Rotator Cuff Repair Through Biological Stimulation
Status: UNKNOWN
Conditions: Rotator Cuff Tear
Interventions: PROCEDURE: Arthroscopic Rotator Cuff Repair|PROCEDURE: Micro-perforations|PROCEDURE: Artelon®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CD19 CAR-T Expressing IL-7 and CCL19 Combined With Anti-PD1 in RR-DLBCL
Status: RECRUITING
Conditions: Diffuse Large B-cell Lymphoma
Interventions: COMBINATION_PRODUCT: CD19-7×19 CAR-T combined with Tislelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Performance and Safety of Carbopol 980 NF 0.2%- Based Medical Device in the Management of Patients With Glaucomar or Ocular Hypertension and Concomitant Dry Eye Syndrome on Multiple Long-term Topical Hypotensive Therapy
Status: RECRUITING
Conditions: Dry Eye Syndrome|Glaucoma and Concomitant Dry Eye Syndrome|Ocular Hypertension and Concomitant Dry Eye Syndrome|Multiple Long-term Topical Hypotensive Therapy
Interventions: DEVICE: Iridium A Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Melatonin Supplementation for Cancer-related Fatigue in Patients Receiving Radiotherapy
Status: TERMINATED
Conditions: Breast Cancer - Female
Interventions: DRUG: Melatonin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: SPACE Trial: Pyridostigmine vs Placebo in SMA Types 2, 3 and 4
Status: COMPLETED
Conditions: Spinal Muscular Atrophy|SMA|Kugelberg-Welander Disease
Interventions: DRUG: Pyridostigmine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Oral Glucose Solution as Pain Relief in Newborns: Results of a Clinical Trial
Status: UNKNOWN
Conditions: Pain
Interventions: OTHER: glucose 10%|OTHER: 20% glucose|OTHER: glucose 30%|OTHER: sterile water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Upper Limb Mirror Therapy With Bilateral Transcutaneous Electrical Nerve Stimulation to Improve Upper Limb Functions in Patients With Stroke
Status: RECRUITING
Conditions: Stroke
Interventions: DEVICE: Bilateral Transcutaneous electrical nerve stimulation (Bi-TENS)|BEHAVIORAL: Mirror Therapy (MT)|BEHAVIORAL: sham-Mirror Therapy (sham-MT)|BEHAVIORAL: Conventional Rehabilitation Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Health Professional Learners' Competence in Newborn Positioning and Attachment Following a Standardized Patient-led Lactation Skills Workshop
Status: COMPLETED
Conditions: Breastfeeding|Patient Simulation
Interventions: OTHER: Breastfeeding Skills Workshop
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER