pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: PROstate CAncer Radiotherapy - Bowel Quality of Life (PROCAR-BQ)
Status: COMPLETED
Conditions: Prostate Cancer|Radiotherapy Side Effect|Bowel Dysfunction|Quality of Life
Interventions: OTHER: Bowel symptoms & QoL assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety and Potential Efficacy of Human Mesenchymal Stem Cells in Non-Cystic Fibrosis Bronchiectasis
Status: COMPLETED
Conditions: Bronchiectasis
Interventions: BIOLOGICAL: hMSCs
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mobile Phone Reminders (and Photovoice) for Routine Immunization in Nigeria - The MOPING Study
Status: UNKNOWN
Conditions: Immunization; Infection
Interventions: BEHAVIORAL: Reminder module (SMS and Phone call)|BEHAVIORAL: Photovoice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Efficacy and Safety of AZD4547 Versus Paclitaxel in Patients With Advanced Gastric or Gastro-oesophageal Cancer
Status: TERMINATED
Conditions: Gastro-oesophageal Junction Cancer|Gastric Cancer
Interventions: DRUG: AZD4547|DRUG: paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Enamel Remineralization Potential of Dentifrices in Situ
Status: COMPLETED
Conditions: Dental Caries
Interventions: DRUG: NaF|DRUG: SnF|DRUG: NaMFP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Tolerability of PG110 in Patients With Knee Osteoarthritis Pain
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: BIOLOGICAL: PG110|BIOLOGICAL: PG110|BIOLOGICAL: PG110|BIOLOGICAL: PG110|BIOLOGICAL: PG110|BIOLOGICAL: PG110|BIOLOGICAL: PG110|BIOLOGICAL: PG110|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: PROTECT Continued Access Post Marketing Surveillance Trial
Status: COMPLETED
Conditions: Coronary Artery Disease, Autosomal Dominant, 1
Interventions: DEVICE: Endeavor® Zotarolimus Eluting Coronary Stent System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intrahepatic Chemotherapy to Patients With Non-resectable Liver Metastases From Solid Tumor
Status: UNKNOWN
Conditions: Liver Metastasis
Interventions: DRUG: Oxaliplatin|DRUG: Mitomycin + Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Maintenance Chemotherapy Versus Consolidative Stereotactic Body Radiation Therapy (SBRT) Plus Maintenance Chemotherapy for Stage IV Non-Small Cell Lung Cancer (NSCLC): A Randomized Phase II Trial
Status: COMPLETED
Conditions: Stage IV Non-Small Cell Lung Cancer
Interventions: RADIATION: Stereotactic Body Radiation Therapy|DRUG: Maintenance chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety of and Immune Response to a Prime-Boost Vaccine Regimen in HIV-Uninfected Vaccine-Naive Adults
Status: COMPLETED
Conditions: HIV Infections
Interventions: BIOLOGICAL: pGA2/JS7 DNA vaccine|BIOLOGICAL: Placebo|BIOLOGICAL: MVA/HIV62 vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Comparing Effect and Change Processes in Cognitive Behavioral Therapy and Emotion-Focused Therapy for Depression
Status: ACTIVE_NOT_RECRUITING
Conditions: Depression
Interventions: BEHAVIORAL: Cognitive Behavioral Therapy|BEHAVIORAL: Emotion-Focused Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Tapering of Analgosedation and Occurrence of Withdrawal Syndrome in Paediatric Intensive Care Treatment
Status: COMPLETED
Conditions: Drug Withdrawal Symptoms|Critical Care|Child
Interventions: OTHER: Algorithm for tapering og analgosedation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Coordinating Pragmatic Primary Care Population Management for Obesity
Status: COMPLETED
Conditions: Obesity|Cardiovascular Risk Factor
Interventions: BEHAVIORAL: Outreach Support for Weight Loss Goal Setting and Self-Weighing|BEHAVIORAL: Outreach Decision Support to Encourage Linkages to Intensive Community Lifestyle Interventions|BEHAVIORAL: Adaptive Tailoring of Information Delivery and Intensity of Primary Care Outreach Support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: "Comparison of the Effectiveness of Conventional Radiofrequency Thermocoagulation and Chemical Ablation With Phenol on Articular Branches of Femoral and Obturator Nerves in Chronic Hip Pain"
Status: NOT_YET_RECRUITING
Conditions: Chronic Pain
Interventions: DRUG: Sedative
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 3 Trial to Evaluate the Efficacy and Safety of Aficamten Compared to Metoprolol Succinate in Adults With Symptomatic oHCM
Status: RECRUITING
Conditions: Obstructive Hypertrophic Cardiomyopathy (oHCM)
Interventions: DRUG: Aficamten (CK-3773274) (5 mg, 10 mg, 15 mg and 20 mg)|DRUG: Placebo to match aficamten|DRUG: Metoprolol succinate (50 mg, 100 mg, 150 mg and 200 mg)|DRUG: Placebo to match metoprolol succinate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of the Eating Rate of Ultra-processed Foods on Dietary Intake Behavior and Metabolic Responses
Status: RECRUITING
Conditions: Eating Rate
Interventions: OTHER: ultra-processed slow eating rate diet|OTHER: Ultra-processed fast eating rate diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Performance and Safety of Vaginal Ring Applicator in Healthy Females (MK-8342A-063)
Status: COMPLETED
Conditions: Contraception: Optional Applicator for Insertion of Vaginal Ring
Interventions: DRUG: Placebo vaginal ring|DEVICE: Single-use, non-sterile applicator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Acupuncture for Degenerative Lumbar Spinal Stenosis
Status: COMPLETED
Conditions: Degenerative Lumbar Spinal Stenosis
Interventions: DEVICE: acupuncture|DEVICE: placebo needle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Topical Agents With Various Antioxidant Containts on Photodamage Skin Induced
Status: ACTIVE_NOT_RECRUITING
Conditions: Photodamaged Skin
Interventions: COMBINATION_PRODUCT: Antioxidants|COMBINATION_PRODUCT: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Assessment of the Effectiveness of Ethosuximide in the Treatment of Peripheral Neuropathic Pain.
Status: COMPLETED
Conditions: Neuropathic Traumatic Pain|Pain NRS ≥ 4|Peripheral Neuropathic Pain|Neuropathic Pain Diagnostic Questionnaire (DN4) ≥ 4
Interventions: DRUG: Zarontin® (ethosuximide) and Stodal®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Proton Beam Therapy in Hepatocellular Carcinoma With Portal Vein Tumor Thrombosis
Status: COMPLETED
Conditions: Liver Neoplasm|Portal Vein Tumor Thrombosis|Proton Therapy
Interventions: RADIATION: Proton beam therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Miltefosine/Paromomycin Phase III Trial for Treatment of Primary Visceral Leishmaniasis (VL) Patients in Eastern Africa
Status: COMPLETED
Conditions: Visceral Leishmaniasis
Interventions: DRUG: Miltefosine|DRUG: Paromomycin|DRUG: Sodium stibogluconate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Efficacy of Hybenix vs Chlosite Gels in Peri-implantitis
Status: ENROLLING_BY_INVITATION
Conditions: Peri-Implantitis
Interventions: OTHER: Hybenix gel|OTHER: Chlosite gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 18F-DCFPyL Imaging as a Method to Assess Treatment Response to Stereotactic Body Radiation Therapy
Status: RECRUITING
Conditions: Localized Prostate Cancer
Interventions: DRUG: 18F-DCFPyL
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I/IIa Study to Investigate the GM-XANTHO in Healthy Volunteers and Atopic Dermatitis Patients
Status: RECRUITING
Conditions: Atopic Dermatitis
Interventions: DRUG: GM-XANTHO onitment|DRUG: Placebo onitment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Study to Investigate the Efficacy and Safety of Mexiletine in Patients With Myotonic Dystrophy Type 1 and Type 2
Status: WITHDRAWN
Conditions: Myotonic Dystrophy Type 1 and Type 2
Interventions: DRUG: Mexiletine 167 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cervical Stabilization Exercises on Bruxism and Sleep Quality
Status: NOT_YET_RECRUITING
Conditions: Bruxism|Sleep Quality|Cervical Stabilization Exercise
Interventions: OTHER: Cervical spinal stabilization exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Phase I/II Study of Lapatinib in Combination With Paclitaxel as 1L Chemotherapy for ErbB2-positive MBC
Status: COMPLETED
Conditions: Neoplasms, Breast
Interventions: DRUG: Lapatinib in combination with weekly paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Electroencephalography Predictors of Repetitive Transcranial Magnetic Stimulation in Obsessive-Compulsive Disorder
Status: COMPLETED
Conditions: Obsessive Compulsive Disorder (OCD)
Interventions: DEVICE: Continuous theta burst stimulation (cTBS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Everolimus (RAD001) for the Treatment of Malignant Pleural Mesothelioma With Merlin/NF2 Loss as a Biomarker to Predict Sensitivity
Status: COMPLETED
Conditions: Malignant Pleural Mesothelioma
Interventions: DRUG: everolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Adjustable Intragastric Balloon in Obese Non-alcoholic Fatty Liver Disease
Status: UNKNOWN
Conditions: Non-Alcoholic Fatty Liver Disease|Non-Alcoholic Steatohepatitis|Obesity|Diabetes Mellitus, Type 2
Interventions: DEVICE: Spartz Balloon
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endoscopic Management of Acute Sigmoid Volvulus in High Risk Surgical Eldery Patients: A Randomized Controlled Trial.
Status: COMPLETED
Conditions: Elderly Patient Withsigmoid Volvulus
Interventions: PROCEDURE: endoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Validation of the Efficacy of the Tool GIMIAS® for the Assessment of Left Atrial Fibrosis in a Group of Healthy Volunteers (RESTORE-HV)
Status: COMPLETED
Conditions: Left Atrial Fibrosis
Interventions: DRUG: gadobutrol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: BK Virus in Salivary Gland Disease: Treating the Potential Etiologic Agent
Status: COMPLETED
Conditions: HIV|Salivary Gland Disease|Benign Lymphoepithelial Lesion
Interventions: DRUG: Ciprofloxacin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Continuous Compressions With Asynchronous Ventilations Using I-gel Device Versus 30:2 Approach During Simulated OHCA
Status: COMPLETED
Conditions: Cardiac Arrest|Cardiopulmonary Arrest|Emergency Medical Services|Resuscitation
Interventions: DEVICE: I-gel® supraglottic device|DEVICE: Face mask ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Non-Pharmacologic Patient Centered Pain Control Adjuncts During First Trimester Abortion
Status: COMPLETED
Conditions: Pregnancy Termination|Pain Management
Interventions: BEHAVIORAL: Non-pharmacologic pain control adjuncts
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Efficacy of Inhaled OligoG CF-5/20 for the Treatment Cystic Fibrosis
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: OligoG CF-5/20
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Selective Lymph Node Dissection for cT1N0M0 Invasive NSCLC With CTR>0.5 Located in the Apical Segment (ECTOP-1018)
Status: RECRUITING
Conditions: Lung Adenocarcinoma|Lymph Node Metastasis
Interventions: PROCEDURE: Selective Lymph Node Dissection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment and Companion Diagnostics of Lower Back Pain Using SCENAR and Passive Medical Radiometry (MWR)
Status: COMPLETED
Conditions: Low Back Pain, Recurrent
Interventions: DIAGNOSTIC_TEST: Microwave Radiometry|DEVICE: SCENAR-CHENS-01|COMBINATION_PRODUCT: Traditional Combination Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Safety and Efficacy Study of Dissolve™ in Treatment of Coronary Small Vessel Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Coronary Small Vessel Disease
Interventions: DEVICE: Cohort A: Dissolve™|DEVICE: Cohort A: Resolute™ Integrity|DEVICE: Cohort B: Dissolve™-2.00mm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Acute Exercise on BDNF Levels in Rheumatoid Arthritis Patients
Status: UNKNOWN
Conditions: Rheumatoid Arthritis
Interventions: OTHER: Aerobic exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mindfulness-based Intervention for Postnatal Depression
Status: UNKNOWN
Conditions: Postnatal Depression
Interventions: BEHAVIORAL: Mindfulness-based program (MBI-p-R)|BEHAVIORAL: Booklet-based psychoeducation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: STIT-2: Evaluation of Safety and Efficacy of Short-time TNI® Treatment in Patients With COPD and Hypercapnia
Status: UNKNOWN
Conditions: COPD|Hypercapnia
Interventions: DEVICE: Nasal oxygen insufflation with a TNI® 20 oxy device|DEVICE: Nasal insufflation of oxygen
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study to Compare Two Treatments for Axillary Hidradenitis Suppurativa: Carbon Dioxide Laser Versus Surgical Deroofing
Status: COMPLETED
Conditions: Hidradenitis Suppurativa
Interventions: PROCEDURE: CO2 (carbon dioxide) laser|PROCEDURE: Surgical Deroofing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Efficacy and Safety of Fasinumab in Patients With Moderate-to-Severe Chronic Low Back Pain and Osteoarthritis of the Hip or Knee
Status: TERMINATED
Conditions: Chronic Low Back Pain|Osteoarthritis
Interventions: DRUG: Fasinumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Changes in Ocular Rigidity After Trabeculectomy in Patients With POAG
Status: COMPLETED
Conditions: Glaucoma|Primary Open Angle Glaucoma|Pseudoexfoliation Glaucoma
Interventions: OTHER: Changes in Ocular rigidity
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study in Healthy Volunteers Evaluating Safety and Pharmacokinetics of Zika Virus Immune Globulin (ZIKV-IG)
Status: COMPLETED
Conditions: Zika Virus Infection|Zika Virus Disease
Interventions: BIOLOGICAL: Zika Virus Immune Globulin (ZIKV-IG)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Investigate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Repeat Doses of RV1729 for 28 Days in Patients With COPD
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: RV1729 28 day repeat dose|DRUG: RV1729 matching placebo 28 day repeat dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: IV Antibiotics With Lavage for Severe PD Peritonitis
Status: COMPLETED
Conditions: Peritonitis|Kidney Failure
Interventions: DRUG: Intravenous vancomycin & gentamicin with adjunctive lavage|DRUG: Intraperitoneal vancomycin & gentamicin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Fat Co-ingestion With Protein on the Post-prandial Anabolic Response in Elderly Men
Status: COMPLETED
Conditions: Sarcopenia
Interventions: DIETARY_SUPPLEMENT: PRO+FAT|DIETARY_SUPPLEMENT: PRO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Influence of Probiotic Supplementation on the Severity of Anxiety and Depressive Symptoms, as Well as the Function and Composition of Gut Microbiota, Metabolic, Inflammation, and Oxidative Stress Markers in Patients With Depression
Status: RECRUITING
Conditions: Depression|Anxiety
Interventions: DIETARY_SUPPLEMENT: Probiotic composed of two bacteria strains: Lactobacillus helveticus Rosell and Bifidobacterium longum Rosell.|OTHER: control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hydrocortisone in the Treatment of Intrusions in Patients With Posttraumatic Stress Disorder
Status: COMPLETED
Conditions: Posttraumatic Stress Disorder
Interventions: DRUG: Arm 1 Hydrocortisone 10 mg|DRUG: Arm 2 Hydrocortisone 30 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Artimes Pro Low Profile Dilatation Catheters for Pre-Dilatation in Patients With Symptomatic Ischemic Heart Disease
Status: COMPLETED
Conditions: Coronary Artery Disease|Heart Disease, Ischemic|Coronary Stenosis
Interventions: DEVICE: Artimes Pro Low Profile Dilatation Catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 2a Study of the Safety, Tolerability, and Pharmacokinetics of Topically Administered PRN473 (SAR444727) in Patients With Mild to Moderate Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: PRN473 (SAR444727)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trans-abdominal Fetal Pulse Oximetry; Tissue Light Scattering and Signal Integrity
Status: RECRUITING
Conditions: Fetal Hypoxia
Interventions: DEVICE: GEN 3 Monitoring of Fetus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Total Laparoscopic Hystrectomy Versus Total Abdominal Hystrectomy
Status: UNKNOWN
Conditions: Effect of Learning Curve on Operative Time in TLH and Comparing it to TAH
Interventions: PROCEDURE: Hystrectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BI 860585 Dose Escalation Single Agent and in Combination With Exemestane or With Paclitaxel in Patients With Various Advanced and/or Metastatic Solid Tumors
Status: COMPLETED
Conditions: Neoplasms
Interventions: DRUG: BI 860585|DRUG: exemestane|DRUG: BI 860585|DRUG: BI 860585|DRUG: paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Smartphone GUIded MeDication AdherencE and Rehabilitation in Patients With Coronary Artery Disease
Status: TERMINATED
Conditions: Coronary Artery Disease|Acute Coronary Syndrome
Interventions: OTHER: BrightHeart®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Phase I Study of ON 01910.Na in Refractory Leukemia or Myelodysplastic Syndrome (MDS)
Status: COMPLETED
Conditions: Acute Myelocytic Leukemia|Acute Lymphocytic Leukemia|Chronic Myelocytic Leukemia|Chronic Lymphocytic Leukemia|Myelodysplastic Syndromes
Interventions: DRUG: ON 01910.Na
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preference for Clarinex Tablets vs. Zyrtec Tablets in Patients With Allergies (P03180)
Status: COMPLETED
Conditions: Seasonal Allergic Rhinitis|Perennial Allergic Rhinitis
Interventions: DRUG: Desloratadine 5 mg (Clarinex)|DRUG: Cetirizine (Zyrtec)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: ARREST-NEPHROSIS - Austrian Resistant Nephrotic Syndrome Treatment Response Registry and Biobank
Status: RECRUITING
Conditions: Focal Segmental Glomerulosclerosis|Proteinuria|Nephrotic Syndrome|Nephrotic Syndrome Steroid-Resistant
Interventions: OTHER: Registry
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Goal-directed vs. Empirical Tranexamic Acid Administrationin Cardiovascular Surgery
Status: RECRUITING
Conditions: Heart Diseases|Vascular Diseases|Transfusion Related Complication|Coagulation Disorder, Blood|Fibrinolysis; Hemorrhage
Interventions: DRUG: TXA administration|DRUG: Placebo administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of Subcutaneous Methylnaltrexone (MNTX) in the Treatment of Opioid-Induced Constipation During Rehabilitation After Orthopedic Procedures
Status: COMPLETED
Conditions: Opioid-induced Constipation
Interventions: DRUG: Methylnaltrexone bromide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Crenolanib for the Treatment of Patients With Advanced GIST With the D842-related Mutations and Deletions in the PDGFRA Gene
Status: COMPLETED
Conditions: D842-related Mutant GIST
Interventions: DRUG: Crenolanib besylate (CP-868,596-26), Dose: 140mg BID
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of HMPL-295S1 in Patients With Advanced Malignant Solid Tumors
Status: RECRUITING
Conditions: Advanced Malignant Solid Tumors
Interventions: DRUG: HMPL-295S1 with dose escalation stage of 5mg up to 200mg, then expansion stage with recommended dose of therapeutic cycle of 28 days .
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stereotactic MRI-guided Adaptive Radiation Therapy (SMART) in One Fraction
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Carcinoma
Interventions: RADIATION: Stereotactic ablative body radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Extension Study of Duloxetine in Osteoarthritis and Knee Pain (Extension of F1J-JE-HMGX, NCT02248480)
Status: COMPLETED
Conditions: Osteoarthritis of the Knee
Interventions: DRUG: Duloxetine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prediction Model fo Screening and Diagnosis of Prostate Cancer in PSA Gray Zone Based on Serum PHI Combined With TPV
Status: UNKNOWN
Conditions: Prostate Cancer|PSA
Interventions: DIAGNOSTIC_TEST: p2PSA|DIAGNOSTIC_TEST: Ultrasonic parameters|DIAGNOSTIC_TEST: Transperineal prostate biopsy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Survival Rates and Quality of Life According to Follow-up Period After Gastrectomy for Gastric Cancer (STOFOLUP)
Status: RECRUITING
Conditions: Gastric Cancer|Recurrence|Quality of Life
Interventions: DIAGNOSTIC_TEST: Computed tomography, Chest X-ray, and blood test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Pegylated Irinotecan NKTR 102 in Treating Patients With Relapsed Small Cell Lung Cancer
Status: COMPLETED
Conditions: Recurrent Small Cell Lung Carcinoma
Interventions: OTHER: Laboratory Biomarker Analysis|DRUG: Pegylated Irinotecan|OTHER: Pharmacological Study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Analysis of the Potential Savings of Rivaroxaban Events Versus Vitamin K Antagonists Events
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DRUG: Rivaroxaban (Xarelto, BAY59-7939)|DRUG: Vitamin K antagonists (VKAs)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Dose Escalation Study in Patients With Relapsed or Refractory DLBCL and MyD88 L265P Mutation
Status: COMPLETED
Conditions: Diffuse Large B Cell Lymphoma
Interventions: DRUG: IMO-8400
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pain and Anxiety Evaluation in Children Using Different Techniques of Local Anesthesia for Dental Treatment
Status: COMPLETED
Conditions: Pediatric Dentistry|Local Anesthesia|Pain Management
Interventions: DEVICE: Local anesthesia with traditional technique|DEVICE: Local anesthesia with computerized technique|DEVICE: Local anesthesia with DentalVibe technique|DRUG: Topic anesthesia|DRUG: Local anesthetic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Study of Protective Effects of Paricalcitol on Inner Layer of Vessels and Its Protective Effect on Inflammation
Status: COMPLETED
Conditions: Chronic Kidney Disease|Endothelial Dysfunction|Inflammation|Hypertension
Interventions: DRUG: paricalcitol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Pully System on Hemiplegic Children
Status: NOT_YET_RECRUITING
Conditions: Cerebral Palsy, Spastic
Interventions: BEHAVIORAL: pulley system exercise regimen|BIOLOGICAL: physical therapy program for CP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Aflibercept With and Without Micropulse Laser in Diabetic Macular Edema
Status: COMPLETED
Conditions: Diabetic Macular Edema
Interventions: DRUG: Aflibercept Injection|OTHER: micropulsed yellow laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Azacitidine for Injection in Myelodysplastic Syndrome (MDS) Patients
Status: COMPLETED
Conditions: Myelodysplastic Syndrome
Interventions: DRUG: Azacitidine for Injection|DRUG: Vidaza®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Lighting Intervention for Cancer-related Fatigue
Status: COMPLETED
Conditions: Breast Cancer|Prostate Cancer|Hematologic Malignancy|Survivorship|Fatigue
Interventions: OTHER: Wearable Sensor|OTHER: Blue-blocking glasses|OTHER: Clear glasses|OTHER: Full SYNC app|OTHER: "Dummy" SYNC app
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Randomized, Double Blind, Placebo-controlled Study to Assess the the Preemptive Benefit of Etoricoxib in Patients Receiving Anterior Cruciate Ligament Reconstruction
Status: COMPLETED
Conditions: Post-operational Pain
Interventions: DRUG: Arcoxia(etoricoxib 90 mg/tablet)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics and Dosimetry of Tc 99m Tilmanocept Following a Single Intravenous Dose Administration in Male and Female Subjects Diagnosed With Rheumatoid Arthritis (RA)
Status: WITHDRAWN
Conditions: Arthritis, Rheumatoid
Interventions: DRUG: Tilmanocept
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Trial of Citalopram for the Prevention of Depression
Status: COMPLETED
Conditions: Depression|HIV Infections|Hepatitis C
Interventions: DRUG: Citalopram|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Major Adverse Limb Events in Patients With Femoro-popliteal and Below-the-knee Peripheral Arterial Disease Treated With Either Sirolimus-coated Balloon or Standard Uncoated Balloon Angioplasty
Status: RECRUITING
Conditions: Peripheral Arterial Disease
Interventions: DEVICE: sirolimus-coated balloon catheter|DEVICE: uncoated balloon catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fertility Sparing Management of EndomeTrial Cancer and Hyperplasia
Status: RECRUITING
Conditions: Endometrial Hyperplasia|Endometrial Cancer|Gynecologic Cancer
Interventions: PROCEDURE: Hysteroscopic uterine resection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CHAMPION-AF Clinical Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Atrial Fibrillation|Stroke|Bleeding
Interventions: DEVICE: WATCHMAN FLX LAAC Device|DRUG: Non-Vitamin K Oral Anticoagulant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Anti-adhesive Effect and Safety of a Mixed Solid of Poloxamer, Gelatin and Chitosan(Mediclore®) After Axillary Dissection for Breast Cancer
Status: UNKNOWN
Conditions: Breastcancer|Surgery: Axillary Dissection
Interventions: DEVICE: adhesive barrier
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Influence of Low Frequency Repetitive Transcranial Stimulation (r-TMS) Treatment on Motor and Cognitive Measurements in Patients With Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DEVICE: Repetitive transcranial stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimal Timing of Transcatheter Aortic Valve Implantation and Percutaneous Coronary Intervention - The TAVI PCI Trial
Status: RECRUITING
Conditions: Aortic Stenosis|Coronary Artery Disease|TAVI|PCI
Interventions: PROCEDURE: PCI before TAVI|PROCEDURE: PCI after TAVI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Biodistribution, Radiation Dosimetry and Pharmacokinetics Study of BAY88-8223 in Japanese Patients
Status: COMPLETED
Conditions: Prostatic Neoplasms
Interventions: DRUG: Radium-223 dichloride (Xofigo, BAY88-8223)|DRUG: Radium-223 dichloride (Xofigo, BAY88-8223)|DRUG: Radium-223 dichloride (Xofigo, BAY88-8223)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Binocular Treatment of Amblyopia Before and After Strabismus Surgery
Status: COMPLETED
Conditions: Amblyopia|Strabismus
Interventions: PROCEDURE: Binocular Treatment|PROCEDURE: Sham Binocular Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Clinical Assessment of Nigella Sativa Oil vs Chlorohexidine as a Therapeutic Aid for Gingivitis, Effect on Gingival IL-6 and IL-18 and Antimicrobial Efficacy.
Status: COMPLETED
Conditions: Gingivitis
Interventions: OTHER: Nigella Sativa oil|DRUG: Chlorhexidine mouthwash
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Efficacy and Safety of Combination Aliskiren/Amlodipine in Patients Not Adequately Responding to Aliskiren Alone
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Aliskiren 300 mg|DRUG: Aliskiren/Amlodipine 300/5 mg|DRUG: Aliskiren/Amlodipine 300/10 mg|DRUG: Placebo to Aliskiren|DRUG: Placebo to Aliskiren/Amlodipine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Battlefield Acupuncture Following Shoulder Surgery
Status: COMPLETED
Conditions: Shoulder Injuries|Pain, Postoperative|Acupuncture, Ear|Pain Management
Interventions: PROCEDURE: Battlefield Acupuncture|PROCEDURE: Standard post-surgical rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Plasma Rich in Growth Factors in Corneal Endothelial Transplantation
Status: NOT_YET_RECRUITING
Conditions: Fuchs' Endothelial Dystrophy|Corneal Edema
Interventions: PROCEDURE: Endothelial keratoplasty|BIOLOGICAL: PRGF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Noninvasive Brain Stimulation to Enhance Cognitive Training in Older Adults
Status: COMPLETED
Conditions: Normal Aging
Interventions: DEVICE: Transcranial Direct Current Stimulation|BEHAVIORAL: Computer-based cognitive therapy (CBCT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Clinical Evaluation of the SportWelding FijiAnchor® in Hand and Hand Wrist Surgery
Status: UNKNOWN
Conditions: Lesion of Ligament of Wrist and/or Hand
Interventions: DEVICE: SportWelding Fiji Anchor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hypofractionated Radiation Therapy in Prostate Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Malignant Neoplasm of Prostate|Local Disease
Interventions: RADIATION: Intensity modulated radiation therapy|RADIATION: Volumetric modulated arc therapy|RADIATION: Image guided radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ovarian Hormone Regulation of Central and Cerebrovascular Hemodynamics (NoMEN Study)
Status: ACTIVE_NOT_RECRUITING
Conditions: Menopause|Estrogen Deficiency|Women|Aging
Interventions: DRUG: GnRH antagonist
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Mindfulness-Based Resilience Training for Aggression, Health, and Stress Among Law Enforcement Officers
Status: COMPLETED
Conditions: Stress, Psychological|Aggression
Interventions: BEHAVIORAL: Mindfulness-Based Resilience Training|BEHAVIORAL: Stress Management Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Microinjected Amnion-derived Collagen by Dermapen in the Smoothing of Skin Wrinkles
Status: COMPLETED
Conditions: Facial Wrinkles - Rough Texture - Hyperpigmentation
Interventions: BIOLOGICAL: Amnion collagen|BIOLOGICAL: Platelet-rich plasma
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Multi-target Tracking in Prostate Radiotherapy Using MLC and KIM
Status: WITHDRAWN
Conditions: Prostate Cancer
Interventions: DEVICE: Combined real-time use of 'Multi-Leaf Collimator Adaptation' and 'kV Intrafraction Monitoring'
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Peri-implant Mucositis and Supportive Peri-implant Therapy
Status: ENROLLING_BY_INVITATION
Conditions: Peri-implant Mucositis
Interventions: DEVICE: Air-Polish|DEVICE: Ultrasonic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hybrid SPECT/CTCA for the Assessment of the Presence and Hemodynamic Significance of CAD in Asymptomatic Patients.
Status: UNKNOWN
Conditions: Hodgkin Lymphoma Treated With Mediastinal Irradiation
Interventions: OTHER: Not relevant (there is no intervention in the present study)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Metformin and Longevity Genes in Prediabetes
Status: COMPLETED
Conditions: Insulin Resistance|Prediabetes|Aging|Inflammation
Interventions: DRUG: Metformin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Low Back Pain and Comorbid Posttraumatic Stress Disorder
Status: UNKNOWN
Conditions: Low Back Pain|Posttraumatic Stress Disorder
Interventions: BEHAVIORAL: Psychotherapy|BEHAVIORAL: Physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prevention of Postoperative Nausea and Vomiting
Status: COMPLETED
Conditions: Postoperative Nausea and Vomiting
Interventions: DRUG: dexamethasone ondansetron|DRUG: Dexamethasone dimenhidrinate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Phase 4 Study - Mucinex D as Adjunct Therapy
Status: COMPLETED
Conditions: Acute Respiratory Infection|Bronchitis|Rhinosinusitis
Interventions: DRUG: Mucinex D (600 mg guaifenesin and 60 mg pseudoephedrine HCl extended-release bi-layer tablets)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Feasibility Safety Study of Benign Centrally-Located Intracranial Tumors in Pediatric and Young Adult Subjects
Status: RECRUITING
Conditions: Benign Centrally-Located Intracranial Tumors
Interventions: DEVICE: ExAblate 4000 System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Controlled Low Calorie Diet in Reducing Side Effects and Increasing Response to Chemotherapy in Patients With Breast or Prostate Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer|Hormone-resistant Prostate Cancer|Recurrent Prostate Cancer
Interventions: DIETARY_SUPPLEMENT: dietary intervention|PROCEDURE: nutritional support|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Evaluate the Safety and Effectiveness of Three Asoprisnil Doses in the Treatment of Women With Endometriosis
Status: COMPLETED
Conditions: Endometriosis
Interventions: DRUG: Asoprisnil|DRUG: Asoprisnil|DRUG: Asoprisnil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: FDG-PET in Advanced Melanoma
Status: TERMINATED
Conditions: Recurrent Melanoma|Stage IIIA Melanoma|Stage IIIB Melanoma|Stage IIIC Melanoma|Stage IV Melanoma
Interventions: DIAGNOSTIC_TEST: [18F]fluorodeoxyglucose|OTHER: Molecular assays on biopsied tissue|DEVICE: positron emission tomography|DEVICE: computed tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy and Safety of SBRT Combined With Atezolizumab Plus Bevacizumab vs Atezolizumab Plus Bevacizumab in Treating Unresectable Advance Hepatocellular Carcinoma.
Status: NOT_YET_RECRUITING
Conditions: Advanced Hepatocellular Carcinoma
Interventions: OTHER: No intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Powerbreath Versus Transcutaneous Electrical Diaphragmatic Stimulation on The Severity of Copd
Status: RECRUITING
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DEVICE: powerbreath|DEVICE: TRANSCUTANEOUS ELECTRICAL DIAPHRAGMATIC STIMULATION
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Prospective, Single-arm, Exploratory Clinical Study of Sintilimab Injection in Combination With Paclitaxel (Albumin-bound) and Gemcitabine in Translational Therapy in Patients With Unresectable Locally Advanced Pancreatic Cancer.
Status: UNKNOWN
Conditions: Unresectable Locally Advanced Pancreatic Cancer
Interventions: DRUG: Sintilimab; Gemcitabine; Albumin-paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Docetaxel With or Without Thalidomide in Treating Patients With Metastatic Prostate Cancer
Status: COMPLETED
Conditions: Stage IV Prostate Cancer|Adenocarcinoma of the Prostate|Recurrent Prostate Cancer
Interventions: DRUG: docetaxel|DRUG: thalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: A Supervised Clinic-to-Community Exercise Intervention to Improve Cardiometabolic Health in Survivors of AYA Cancer
Status: WITHDRAWN
Conditions: Cardiometabolic Dysregulation|Young Adult Cancer|Adolescent Cancer|Body Composition
Interventions: OTHER: Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: "Mobile Stroke Unit"-Concept for Delivery of Specialized Acute Stroke Care to Patients in Remote Areas
Status: COMPLETED
Conditions: Acute Stroke
Interventions: DEVICE: MSU-based stroke management|DEVICE: Control stroke management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study on the Efficacy and Tolerance of a New Anti-regurgitation Infant Formula (STELLAR)
Status: UNKNOWN
Conditions: Gastroesophageal Reflux in Children
Interventions: OTHER: Experimental Infant formula|OTHER: Infant formula thickened with locust bean gum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT