pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Look at Food and Lose Your Fear - Evaluation of a Computerized Attention Training (CAT) for Anorexia Nervosa Patients
Status: UNKNOWN
Conditions: Anorexia Nervosa
Interventions: BEHAVIORAL: Computerized attention training (CAT)|BEHAVIORAL: Sham computerized attention training (control condition)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Tecovirimat for Treatment of Monkeypox Virus
Status: RECRUITING
Conditions: Monkeypox
Interventions: DRUG: Tecovirimat Oral Capsule|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: To Study the Effects of Aliskiren on Albuminuria and Various Biomarkers in Patients With Nephropathy
Status: TERMINATED
Conditions: Non-diabetic Nephropathy
Interventions: DRUG: Aliskiren|DRUG: Placebo to Aliskiren|DRUG: Hydrochlorothiazide (HCTZ)|DRUG: Placebo to Hydrochlorothiazide (HCTZ)|DRUG: Ramipril
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study of Chemotherapy in Combination With All-trans Retinoic Acid (ATRA) With or Without Gemtuzumab Ozogamicin in Patients With Acute Myeloid Leukemia (AML) and Mutant Nucleophosmin-1 (NPM1) Gene Mutation
Status: COMPLETED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Gemtuzumab Ozogamicin (Mylotarg)|DRUG: standard chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of a Biophoton Therapy on Patients With Brain Disorders
Status: RECRUITING
Conditions: Brain Disorders - Alzheimer's Disease, Dementia, Parkinson's Disease, Traumatic Brain Injury
Interventions: DEVICE: Biophotonizer - a Biophoton Generator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating a 13-valent Pneumococcal Conjugate Vaccine in Infants
Status: COMPLETED
Conditions: Vaccines, Pneumococcal
Interventions: BIOLOGICAL: 13-valent pneumococcal conjugate vaccine|BIOLOGICAL: 7 valent pneumococcal conjugate vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Clinical Trial to Evaluate the Safety and Efficacy of IBS in Patients With Coronary Artery Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Coronary Artery Disease
Interventions: DEVICE: Sirolimus-Eluting Iron Bioresorbable Coronary Scaffold System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 360 Degree Expanded Diaphragm Exercises in Women With Stress Urinary Incontinence
Status: RECRUITING
Conditions: Stress Urinary Incontinence|Diaphragmatic Breathing|Pelvic Floor Muscle Exercise|Intra-abdominal Pressure
Interventions: OTHER: Pelvic floor muscle training with 360 degree expanded diaphragm exercises|OTHER: Pelvic floor muscle training with standard diaphragm exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: China Clinical Trial for Therapeutic MR-HIFU Ablation of Uterine Fibroids
Status: COMPLETED
Conditions: Uterine Fibroids
Interventions: DEVICE: MR-HIFU uterine fibroid treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PMCF Study to Evaluate Performance and Safety of "HPMC-based Eyedrops" Used to Relieve Dry Eye Symptoms
Status: COMPLETED
Conditions: Dry Eye|Dry Eye Disease|Kerato Conjunctivitis Sicca
Interventions: DEVICE: Hydroxypropyl methylcellulose eye drops
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Radiotherapy Combined With Albumin Bound Paclitaxel and Nedaplatin for Locally Advanced NSCLC
Status: UNKNOWN
Conditions: Non-small Cell Lung Cancer
Interventions: RADIATION: chest radiation(IMRT)|DRUG: Concurrent chemotherapy twice a week|DRUG: Concurrent chemotherapy once a week
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Three Drug Combinations for Intermittent Treatment of Malaria in Children
Status: COMPLETED
Conditions: Malaria
Interventions: DRUG: SP, amodiaquine, piperaquine, dihdroartemisinin|DRUG: intermittent preventive treatment|DRUG: Du-Cotecxin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Bichectomy: Hydrodissection Technique
Status: COMPLETED
Conditions: Aging
Interventions: PROCEDURE: Bichectomy with hydrodissection|PROCEDURE: Bichectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Peginterferon Beta-1a in Participants With Relapsing Multiple Sclerosis
Status: COMPLETED
Conditions: Relapsing Multiple Sclerosis
Interventions: DRUG: BIIB017 (peginterferon beta-1a)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lurasidone - A 6-week Study of Patients With Bipolar I Depression (Monotherapy)
Status: COMPLETED
Conditions: Bipolar Depression
Interventions: DRUG: lurasidone|DRUG: lurasidone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Efficacy, Safety, and Tolerability of Sarecycline for Treating Periorificial Dermatitis
Status: COMPLETED
Conditions: Perioral Dermatitis
Interventions: DRUG: Seysara Oral Product
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RCT of Low-dose Clomiphene vs. High Dose Gonadotropin Protocol for IVF Poor Responders
Status: WITHDRAWN
Conditions: Infertility
Interventions: DRUG: Low-dose Clomiphene|DRUG: High dose gonadotropins
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Yoga Versus Health Education for the Treatment of Persistent Fatigue in Patients With Post COVID-19 Syndrome
Status: RECRUITING
Conditions: Post-COVID-19 Syndrome|Fatigue Post Viral
Interventions: BEHAVIORAL: Yoga Therapy|BEHAVIORAL: Health Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics, Bioavailability and Safety of PENNSAID® Gel
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: 2% w/w diclofenac sodium topical gel|DRUG: 1.5% w/w diclofenac sodium topical solution|DRUG: 75 mg diclofenac sodium delayed release tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Auditory Brainstem Implant (ABI) in Children With No Cochleae or Auditory Nerves
Status: RECRUITING
Conditions: Hearing Loss, Bilateral (Causes Other Than Tumors)
Interventions: DEVICE: Nucleus ABI541 Auditory Brainstem Implant
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PTK787/ZK222584 in the Treatment of Metastatic Gastrointestinal Stromal Tumors Resistant to Imatinib
Status: COMPLETED
Conditions: Sarcoma
Interventions: DRUG: PTK787/ZK222584
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Catheter Over Needle (CON) vs Catheter Through Needle (CTN).
Status: RECRUITING
Conditions: Shoulder Disease
Interventions: DEVICE: CON - Contiplex C™ (CC)|DEVICE: CTN - Contiplex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Pharmacodynamics of BIIF 1149 BS in Healthy Young Male Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BIIF 1149 BS - single rising doses|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Transcutaneous Electrical Nerve Stimulation on Pain Intensity of Patients With Hip Arthroplasty
Status: COMPLETED
Conditions: Hip Fractures
Interventions: DEVICE: Experimental. This was the group that received TENS|OTHER: No intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Enzalutamide (Formerly MDV3100) as a Neoadjuvant Therapy for Patients Undergoing Prostatectomy for Localized Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: Enzalutamide|DRUG: Leuprolide|DRUG: Dutasteride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevention of Infection and Incidence of COVID-19 in Medical Personnel Assisting Patients With New Coronavirus Disease
Status: COMPLETED
Conditions: Increased Risk of SARS-CoV-2 Infection
Interventions: DRUG: Bromhexine Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Tolerability and Safety of Subcutaneous Administration of Two Doses of AFFITOPE® PD01A in Early Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: BIOLOGICAL: AFFITOPE® PD01A|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: 18F-DCFPyL PET/CT in High-grade Epithelial Ovarian Cancer (PET HOC)
Status: COMPLETED
Conditions: Stage III Ovarian Cancer|Stage IV Ovarian Cancer
Interventions: DIAGNOSTIC_TEST: 18F-DCFPyL
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: US Guided WALLANT vs CPB Block for Clavicle Surgery
Status: RECRUITING
Conditions: Clavicle Fracture|Clavicle Injury
Interventions: PROCEDURE: WALLANT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Denosumab vs Zoledronate After Lumbar Fusion
Status: RECRUITING
Conditions: Osteopenia|Lumbar Spondylolisthesis
Interventions: DRUG: Denosumab 60 mg/ml [Prolia]|DRUG: Zoledronate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Iloprost on Pulmonary Oxygenation in Patients With Low Diffusing Capacity During One-lung Ventilation
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DRUG: iloprost|DRUG: normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Obstructive Sleep Apnea Treatment and Insulin Sensitivity in Pregnancy
Status: WITHDRAWN
Conditions: Obstructive Sleep Apnea|Pregnancy Related|Insulin Sensitivity
Interventions: DEVICE: Continuous Positive Airway Pressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study of LY3325656 in Healthy Participants and Participants With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: LY3325656|DRUG: Placebo|DRUG: Liraglutide|DRUG: Sitagliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Inter Individual Variability in Initiation Pathway Activation and Regulation and Phenotypic Heterogeneity in Patients With Haemophilia A and B
Status: UNKNOWN
Conditions: Haemophilia
Interventions: DIAGNOSTIC_TEST: Thrombophilia screen|DIAGNOSTIC_TEST: Initiation pathway analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Cardiac Arrest Extra Corporeal Oxygenation Membrane
Status: UNKNOWN
Conditions: Cardiac Arrest|Cardiopulmonary Resuscitation|Advanced Cardiac Life Support|Extracorporeal Life Support
Interventions: PROCEDURE: Fast track access to vaECMO
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Role of PPAR-y Agonists in Immunomodulation and Vascular Prevention in SLE (PPAR-SLE)
Status: COMPLETED
Conditions: Systemic Lupus Erythematosus
Interventions: RADIATION: PET/CT|DRUG: Pioglitazone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: ENdothelial Healing Assessment With Novel Coronary tEchnology
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DEVICE: SYNERGY stent|DEVICE: BVS ABSORB scaffold
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of Gemcitabine-Paclitaxel to Treat Metastatic Breast Cancer
Status: COMPLETED
Conditions: Metastatic Breast Cancer
Interventions: DRUG: gemcitabine|DRUG: paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open Versus Laparoscopic Repair of Perforated Peptic Ulcer
Status: RECRUITING
Conditions: Perforated Peptic Ulcer
Interventions: PROCEDURE: open repair of perforated peptic ulcer|PROCEDURE: laparoscopic repair of perforated peptic ulcer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Laryngeal Mask Airway (LMA) Insertion With Sevoflurane and Remifentanil
Status: COMPLETED
Conditions: Laryngismus
Interventions: DRUG: Remifentanil 1|DRUG: Control|DRUG: Remifentanil 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Dronabinol Versus Placebo in Treatment and Prevention of Highly Active Anti-Retroviral Therapy (HAART)-Related Nausea and Vomiting
Status: COMPLETED
Conditions: Highly Active Antiretroviral Therapy (HAART)-Related Nausea and Vomiting|HIV Infections
Interventions: DRUG: Dronabinol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Fluorodeoxyglucose (FluGlucoScan) in Patients With Breast Cancer: Correlation With Histologic Findings of Sentinel Node Biopsies and Axillary Dissection
Status: TERMINATED
Conditions: Breast Neoplasms
Interventions: PROCEDURE: Positron Emission Tomography Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy and Safety of Tranexamic Acid in Spinal Fusion Surgery
Status: TERMINATED
Conditions: Spinal Fusion
Interventions: DRUG: Sodium Chloride 0.9% Inj|DRUG: Tranexamic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Initial Pain Management in Pediatric Pancreatitis: Opioid vs. Non-Opioid
Status: RECRUITING
Conditions: Acute Pancreatitis
Interventions: DRUG: Ketorolac|DRUG: Opioid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Rilonacept (Arcalyst ®) in the Treatment of Subacromial Bursitis
Status: COMPLETED
Conditions: Subacromial Bursitis
Interventions: DRUG: Rilonacept|DRUG: Corticosteroid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Artesunate Plus Amodiaquine in Malaria in Cote d'Ivoire
Status: COMPLETED
Conditions: Malaria
Interventions: DRUG: Artesunate + Amodiaquine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Duobrii Treatment of Acne Keloidalis Nuchae (AKN)
Status: RECRUITING
Conditions: Acne Keloidalis Nuchae|AKN
Interventions: DRUG: Duobrii|DRUG: Placebo|DRUG: Bryhali
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of HD Chemotherapy Followed by Auto-transplant and R-CHOP in High Risk Patients With DLBCL.
Status: COMPLETED
Conditions: Diffuse Large B-Cell Lymphoma
Interventions: DRUG: Rituximab-HDS|DRUG: Rituximab-CHOP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pulsed Radiofrequency Energy to Treat Post-Bunionectomy Pain
Status: TERMINATED
Conditions: Post-operative Pain
Interventions: DEVICE: Pulsed Radiofrequency Energy (PRFE)|DEVICE: No Pulsed Radiofrequency Energy (PRFE)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of KK2269 in Adult Participants With Solid Tumors
Status: RECRUITING
Conditions: Advanced Solid Tumor|Metastatic Solid Tumor|Gastric Adenocarcinoma|Gastroesophageal Junction Adenocarcinoma|Esophageal Adenocarcinoma|Non Small Cell Lung Cancer
Interventions: DRUG: KK2269|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: IBD Neoplasia Surveillance RCT
Status: RECRUITING
Conditions: Colonic Neoplasms|Inflammatory Bowel Diseases|Dysplasia
Interventions: PROCEDURE: Standard colonoscopy with targeted biopsies
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Physiotherapy Scoliosis Specific Exercise Improves Truncal Shift in Idiopathic Scoliosis
Status: COMPLETED
Conditions: Scoliosis|Apical Deviation|Adolescent Idiopathic Scoliosis
Interventions: OTHER: Physiotherapy Scoliosis Specific Exercise (PSSE)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Anti-PD-1 Antibody and P-GEMOX Chemotherapy Combined With Radiotherapy in High-risk Early-Stage ENKTL
Status: RECRUITING
Conditions: Extranodal NK-T-Cell Lymphoma, Nasal and Nasal-Type|Early-stage|High-Risk Cancer
Interventions: DRUG: Anti-PD-1 monoclonal antibody|DRUG: Pegaspargase|DRUG: Gemcitabine|DRUG: Oxaliplatin|RADIATION: Involved site radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Analgesic Effect of QLB II After Robotic Prostatectomy. (QLB II: Quadratus Lomborum Block II Type)
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: OTHER: Levobupivacaine in QLB II
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I/II Trial of Ribavirin (With Escalation) + Isoprinosine in Asymptomatic HIV-Viremic Patients
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Inosine pranobex|DRUG: Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Caudal Epidural Injections in Treatment of Chronic Low Back and Lower Extremity Pain
Status: COMPLETED
Conditions: Low Back Pain
Interventions: DRUG: Caudal epidural injection|DRUG: Caudal Epidural Injection with generic Celestone|DRUG: Caudal Epidural Injection with Celestone|DRUG: Caudal Epidural Injection with DepoMedrol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Practical Clinical Study Comparing the Fixed-cycle Regimen Containing Orelabrutinib With BTKi Monotherapy
Status: NOT_YET_RECRUITING
Conditions: CLL/SLL
Interventions: DRUG: orelabrutinib|DRUG: FCR/BR|DRUG: BTK inhibitor
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Clinical Study of ICP-488 in Healthy Subjects and Patients With Psoriasis
Status: RECRUITING
Conditions: Psoriasis
Interventions: DRUG: ICP-488|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare Tissue and Liquid Biopsies in People With Different Types of Cancer
Status: RECRUITING
Conditions: Non-Small-Cell Lung Carcinoma|Colorectal Cancer|Pancreatic Ductal Adenocarcinoma
Interventions: DIAGNOSTIC_TEST: Liquid biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effects of Vestibular Exercise and Cervical Stabilization Exercise Training on Balance and Gait in MS Patients
Status: RECRUITING
Conditions: Multiple Sclerosis|Vestibular|Exercises
Interventions: OTHER: Exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Automatic Oxygen Control (SPOC) in Preterm Infants
Status: UNKNOWN
Conditions: Infantile Respiratory Distress Syndrome|Ventilator Lung; Newborn
Interventions: DEVICE: SPOCnew|DEVICE: 8s SpO2 averaging|DEVICE: SPOCold|DEVICE: 2s SpO2 averaging
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Robotic Assisted Knee Arthroplasty - Retain the Anterior Cruciate Ligament or Not
Status: NOT_YET_RECRUITING
Conditions: Arthritis Knee|Arthroplasty|Gait Analysis
Interventions: DEVICE: Journey II CR|DEVICE: Journey II XR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Oxidative Stress Lowering Effect of Simvastatin and Atorvastatin.
Status: UNKNOWN
Conditions: Diabetes Mellitus|Hypertension
Interventions: DRUG: atrorvastatin 10mg|DRUG: simvastatin 40mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Phase III Study to Evaluate the Efficacy and Safety of ASP0456 in Patients With Constipation Predominant Irritable Bowel Syndrome
Status: COMPLETED
Conditions: Irritable Bowel Syndrome With Constipation (IBS-C)
Interventions: DRUG: linaclotide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Family Treatment for Adolescents With Anorexia Nervosa
Status: COMPLETED
Conditions: Anorexia Nervosa|Subthreshold Anorexia Nervosa|Eating Disorder Not Otherwise Specified, Primarily Restriction
Interventions: BEHAVIORAL: Acceptance-based separated family treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I Trial to Assess the Safety, Tolerability and Immunogenicity of a Ebola Virus Vaccine (rVSVΔG-ZEBOV-GP)
Status: COMPLETED
Conditions: Hemorrhagic Fever, Ebola
Interventions: BIOLOGICAL: rVSVΔ-ZEBOV-GP
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: FUSCC Refractory TNBC Umbrella (FUTURE)
Status: UNKNOWN
Conditions: Triple-negative Breast Cancer
Interventions: DRUG: Pyrotinib with Capecitabine|DRUG: AR inhibitor combined with everolimus(B1) or CDK4/6 inhibitor(B2),or EZH2 inhibitor (B4)|DRUG: anti PD-1 with nab-paclitaxel|DRUG: PARP inhibitor included therapy|DRUG: BLIS with anti-VEGFR included therapy|DRUG: MES with anti-VEGFR included therapy|DRUG: mTOR inhibitor with nab-paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hyaluronic Acid for the Prevention of Endocavitary Synechiae After Myomectomy
Status: UNKNOWN
Conditions: Patients With an Indication for Myomectomy or Polymyomectomy
Interventions: DEVICE: GEL GROUP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Comparative PK Study of Econazole Nitrate Foam and Econazole Nitrate Cream in Subjects With Interdigital Tinea Pedis Aged 12 Years to Less Than 18 Years
Status: COMPLETED
Conditions: Interdigital Tinea Pedis
Interventions: DRUG: Econazole Nitrate|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Mindfulness to the Clinical Setting: The Mind Hand Connection Study
Status: COMPLETED
Conditions: Mindfulness|Education, Medical|Hand Hygiene|Patient Safety
Interventions: BEHAVIORAL: Mindfulness Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Post Prandial Glucose Control Proof-of-Principle
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: OTHER: Carbohydrate placebo|OTHER: Nutritional ingredient|OTHER: #1 Nutritional ingredient +Fiber|OTHER: #2 Nutritional ingredient + Fiber|OTHER: #3 Nutritional ingredient + Fiber
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Active Symptom Control With or Without Chemotherapy in Treating Patients With Malignant Pleural Mesothelioma
Status: COMPLETED
Conditions: Malignant Mesothelioma
Interventions: DRUG: cisplatin|DRUG: mitomycin C|DRUG: vincristine sulfate|DRUG: vinorelbine tartrate|PROCEDURE: pain therapy|PROCEDURE: psychosocial assessment and care|PROCEDURE: quality-of-life assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Sentinel Lymph Node Biopsy in Stage AI-IIA Germ Cell Tumors
Status: RECRUITING
Conditions: Testicular Germ Cell Tumor
Interventions: PROCEDURE: Orchofuniculectomy with simultaneous laparoscopic biopsy of the sentinel lymph node using indocyanine green dye with/without methylene blue dye.|DIAGNOSTIC_TEST: Radiopharmaceutical administration (Technetium/methylene blue)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Plasma Level of Various Omega-3 Lipids
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: OM3-FFA|DIETARY_SUPPLEMENT: OM3-MAG|DIETARY_SUPPLEMENT: OM3-EE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Digital Delivery of Information About Genetic Testing for Breast Cancer
Status: COMPLETED
Conditions: Breast Neoplasm Female
Interventions: OTHER: Digital Delivery of Pre-Genetic Testing Information via the BRCA-DIRECT Platform|OTHER: Digital Delivery of Genetic Test Results via the BRCA-DIRECT Platform
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Motivational Interviewing and Cognitive Behavioural Therapy for Generalized Anxiety Disorder
Status: COMPLETED
Conditions: Anxiety Disorders|Generalized Anxiety Disorder
Interventions: BEHAVIORAL: Motivational Interviewing and Cognitive Behavioural Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Will Autologous Platelet Rich Plasma Able To Restore Ovarian Function?
Status: ACTIVE_NOT_RECRUITING
Conditions: Infertility|IVF|Premature Ovarian Failure|Anti-Mullerian Hormone Deficiency
Interventions: OTHER: autologous platelet rich plasma|OTHER: saline solution
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Liposomal Bupivacaine vs Continuous Nerve Catheters for Below the Knee Amputations
Status: RECRUITING
Conditions: Pain, Postoperative|Amputation
Interventions: DRUG: Liposomal bupivacaine|DRUG: Bupivacaine Hydrochloride 0.5 % Injectable Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: The Effect of Air Pollution on Lung Health Among School Children Living in Haifa Bay Region
Status: COMPLETED
Conditions: Bronchial Asthma|Signs and Symptoms, Respiratory|Allergy
Interventions: DEVICE: Spirometry (Pony spirometer)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Tolerability and Efficacy of Adjuvant T-DM1 in Patients With HER2 Positive Breast Cancer After Incomplete Pathological Response to Neoadjuvant Chemotherapy Including Anti-HER2 Agents. Real-world Multicenter Retrospective-prospective Study
Status: RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: T-DM1 adjuvant
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: HDM201 and Midostaurin (HDMM) in Relapsed/Refractory AML With FLT3mut and TP53wt.
Status: TERMINATED
Conditions: AML, Adult
Interventions: DRUG: HDM201|DRUG: Midostaurin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study Using Weightloss and Exercise to Prevent Recurring Gestational Diabetes in Obese Women
Status: COMPLETED
Conditions: Gestational Diabetes
Interventions: BEHAVIORAL: Prevention of recurrent gestational diabetes through weight loss and exercise (English & Spanish)|BEHAVIORAL: Lifestyle education (English & Spanish)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Corticosteroids With Vedolizumab in Crohn's Disease
Status: TERMINATED
Conditions: Crohn's Disease
Interventions: DRUG: Prednisone|DRUG: Placebo|DRUG: Vedolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fulvestrant + Neratinib In Breast Cancer
Status: WITHDRAWN
Conditions: Stage IV (Metastatic) Breast Cancer|Metastatic Breast Cancer|ER Positive Breast Cancer|PR-Positive Breast Cancer|HER2-negative Breast Cancer|Invasive Breast Cancer
Interventions: DRUG: NERATINIB|DRUG: FULVESTRANT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oropharyngeal Administration of Mother's Colostrum for Premature Infants (NS-72393-360)
Status: COMPLETED
Conditions: Infection|Enterocolitis, Necrotizing|Ventilator-associated Pneumonia
Interventions: OTHER: oropharyngeal mother's milk|OTHER: oropharyngeal sterile water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Topical Pancreatic Duct Lidocaine for Prevention of Post-ERCP Pancreatitis
Status: COMPLETED
Conditions: Pancreatitis
Interventions: DRUG: Lidocaine Hydrochloride|DRUG: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Radiation Therapy Outreach Program for Minority or Low-Income Patients With Newly Diagnosed Cancer
Status: COMPLETED
Conditions: Psychosocial Effects of Cancer and Its Treatment|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: OTHER: counseling intervention|OTHER: study of socioeconomic and demographic variables|PROCEDURE: psychosocial assessment and care
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Aurinia Renal Response in Active Lupus With Voclosporin
Status: COMPLETED
Conditions: Lupus Nephritis
Interventions: DRUG: Voclosporin|DRUG: Placebo Oral Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pre-transplant Purging and Post-transplant MRD-guided Maintenance Therapy With Elranatamab in Patients With High-risk Multiple Myeloma
Status: RECRUITING
Conditions: Multiple Myeloma|Post-transplant MRD-guided Maintenance Therapy|Pre-transplant Purging
Interventions: DRUG: Elranatamab|DRUG: Lenalidomide|DRUG: Plerixafor|DRUG: Melphalan|DRUG: Busulfan|DRUG: G-CSF|PROCEDURE: Stem cell transplant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial to Evaluate the Safety of Lovastatin in Individuals With Neurofibromatosis Type I (NF1)
Status: COMPLETED
Conditions: Neurofibromatosis 1
Interventions: DRUG: Lovastatin|DRUG: Lovastatin|DRUG: placebo pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nutrition for Brain and Body Health (BB-Health) Feasibility Trial
Status: UNKNOWN
Conditions: Cognition|Obesity
Interventions: OTHER: Multicomponent nutrition supplement (MCNS)|BEHAVIORAL: Behavioral weight loss program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Probiotics in Patients With Ulcerative Colitis
Status: WITHDRAWN
Conditions: Ulcerative Colitis
Interventions: DIETARY_SUPPLEMENT: Kyo-Dophilus|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Diclofenac Premedication, as the Effect of Preemptive Analgesia After Post-thoracotomy Chest and Shoulder Pain
Status: COMPLETED
Conditions: Pain|Inadequate or Impaired Respiratory Function
Interventions: DRUG: Diclofenac|DRUG: Midazolam|DRUG: Atropine|DRUG: bucain + fentanyl|DRUG: Nalbuphine|DRUG: Diclofenac|DRUG: Metamizole-sodium|DRUG: Tramadol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study to Evaluate DNTH103 in Adults With Multifocal Motor Neuropathy
Status: NOT_YET_RECRUITING
Conditions: Multifocal Motor Neuropathy
Interventions: DRUG: DNTH103|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Utility of FDG-PET Scan on the Selection of Patients for Resection of Hepatic Colorectal Metastases
Status: COMPLETED
Conditions: Colorectal Liver Metastases|Colorectal Cancer|Neoplasm Metastasis
Interventions: PROCEDURE: FDG-PET scan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Vale+ Tu Salud: Corner-Based Randomized Trial to Test a Latino Day Laborer Program Adapted to Prevent COVID-19
Status: COMPLETED
Conditions: COVID-19
Interventions: BEHAVIORAL: COVID-19 Group Problem Solving|BEHAVIORAL: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Feasibility of a Virtual Smoking Cessation Program
Status: RECRUITING
Conditions: Smoking|Smoking Cessation|Smoking Reduction|Perioperative/Postoperative Complications|Fractures, Bone
Interventions: BEHAVIORAL: Virtual Smoking Cessation Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Protracted Mixture of Local Anesthetics for Major Foot and Ankle Surgery
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: Bupivacaine|DRUG: Epinephrine|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Efficacy of Preventive Dosing of Fondaparinux Sodium Versus Placebo for the Prevention of Venous Thromboembolism (VTE) in Patients Undergoing Coronary Bypass Surgery Receiving Routine Mechanical Prophylaxis
Status: TERMINATED
Conditions: Deep Vein Thrombosis|Coronary Artery Bypass Surgery|Venous Thromboembolism
Interventions: DRUG: Fondaparinux|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Urogenital Schistosomiasis and Sexually Transmitted Infections in Madagascar
Status: COMPLETED
Conditions: Sexually Transmitted Infections|Schistosoma Haematobium
Interventions: DRUG: Treatment with anti-STI and anti-schistosoma regimens
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Strata PATH™ (Precision Indications for Approved Therapies)
Status: ACTIVE_NOT_RECRUITING
Conditions: Cancer|Advanced Solid Tumor
Interventions: DRUG: lorlatinib|DRUG: encorafenib + binimetinib|DRUG: talazoparib|DRUG: sacituzumab govitecan|DRUG: axitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Virtual Teach-to-Goal Education vs. Brief Education for Children
Status: COMPLETED
Conditions: Asthma|Bronchospasm|Shortness of Breath
Interventions: BEHAVIORAL: Virtual Teach to Goal|BEHAVIORAL: Brief Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Safety, Tolerability, PK and PD Study of Multiple Oral Doses of SKL15508 in Subjects With Stable Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: SKL15508|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Diode Laser 940 nm in Management of Loss of Taste Sensation
Status: COMPLETED
Conditions: SARS-CoV Infection
Interventions: DEVICE: a 940-nm diode laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Change of Urinary Angiotensinogen Excretion After Valsartan Treatment in Patients With Persistent Proteinuria
Status: UNKNOWN
Conditions: Chronic Kidney Disease|Proteinuria
Interventions: DRUG: valsartan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluating Collagen Cross-Linking (CCL) Treatment in Norway
Status: UNKNOWN
Conditions: Keratoconus
Interventions: PROCEDURE: corneal cross-linking (CCL)|DRUG: Riboflavin/dextran eyedrops|DEVICE: UV-X system
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mentor Mothers: A Sustainable Family Intervention in South African Townships
Status: COMPLETED
Conditions: Human Immunodeficiency Virus|Acquired Immune Deficiency Syndrome|Tuberculosis
Interventions: BEHAVIORAL: Peer support and mentoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: PF-04523655 Dose Escalation Study, and Evaluation of PF-04523655 With/Without Ranibizumab in Diabetic Macular Edema (DME)
Status: COMPLETED
Conditions: Choroidal Neovascularization|Diabetic Retinopathy|Diabetic Macular Edema
Interventions: DRUG: PF-04523655 (Stratum I)|DRUG: ranibizumab|DRUG: PF-04523655 (Stratum II)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Transcranial Laser Therapy for Major Depressive Disorder
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DEVICE: Near-infrared radiation via Transcranial LED Therapy|DEVICE: Sham device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PREVAIL-TF: Transfemoral Placement of Aortic Balloon Expandable Transcatheter Valves Trial (Europe)
Status: COMPLETED
Conditions: Aortic Valve Stenosis
Interventions: DEVICE: Sapien XT™ transcatheter heart valve and delivery system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Remotely Resolving Psychological Stress (Remote RePS)
Status: COMPLETED
Conditions: Post Traumatic Stress Disorder
Interventions: BEHAVIORAL: Personalized Attention Bias Training|BEHAVIORAL: Neutral Attention Training Condition|BEHAVIORAL: Non-Personalized Attention Bias Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluate the Safety and Efficacy of HDM1002 Tablets in Overweight and Obese Adults
Status: NOT_YET_RECRUITING
Conditions: Overweight and Obesity
Interventions: DRUG: HDM1002 100 mg QD|DRUG: HDM1002 200 mg QD 12weeks|DRUG: HDM1002 400 mg QD 12weeks|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: BSGM to Evaluate Patients With GI Symptoms
Status: RECRUITING
Conditions: Gastrointestinal Motility Disorders in Children|Functional Gastrointestinal Disorders|Gastroparesis|Dyspepsia and Other Specified Disorders of Function of Stomach
Interventions: DEVICE: Body surface gastric mapping device
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase II Evaluation of Afatinib in Patients With Persistent or Recurrent HER2-positive Uterine Serous Carcinoma
Status: RECRUITING
Conditions: HER2/Neu+ Uterine Serous Carcinoma
Interventions: DRUG: Afatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Prospective Study of the Kidney Protective Effect of Aliskiren in Hypertensive Patients With IgA Nephropathy
Status: UNKNOWN
Conditions: Glomerulonephritis, IGA|Hypertension
Interventions: DRUG: aliskiren
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Incretin-based Drugs and Pancreatic Cancer
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: DPP-4 inhibitors|DRUG: GLP-1 analogs|DRUG: Sulfonylureas|DRUG: Biguanides|DRUG: Thiazolidinediones|DRUG: Alpha-glucosidase inhibitors|DRUG: Meglitinides
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Guadecitabine and Pembrolizumab in Treating Patients With Recurrent Ovarian, Primary Peritoneal, or Fallopian Tube Cancer
Status: COMPLETED
Conditions: Recurrent Fallopian Tube Carcinoma|Recurrent Ovarian Carcinoma|Recurrent Primary Peritoneal Carcinoma
Interventions: DRUG: Guadecitabine|OTHER: Laboratory Biomarker Analysis|BIOLOGICAL: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Apixaban Evaluation of Interrupted Or Uninterrupted Anticoagulation for Ablation of Atrial Fibrillation
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DRUG: Interrupted apixaban|DRUG: Uninterrupted apixaban
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Concordance of Two Endoscopic Procedures for Diagnosis of Carcinoma of the Upper Aerodigestive Tract
Status: WITHDRAWN
Conditions: Upper Aerodigestive Tract Lesions|Neoplasms, Oropharyngeal|Oropharyngeal Cancer|Neoplasms, Hypopharyngeal|Hypopharyngeal Cancer|Head and Neck Neoplasms|UADT Neoplasms|Carcinoma, Squamous Cell|Papilloma
Interventions: DEVICE: Direct Rigid Endoscopy|DEVICE: Transnasal Flexible Endoscopy with Narrowband Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Analgesic Efficacy of Intravenous Lidocaine and/or Ketamine
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: Lidocaine,|DRUG: Ketamine|DRUG: association ketamine-lidocaine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT