pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Study of Prevention and Treatment of Postmenopausal Osteoporosis in Chinese Women
Status: COMPLETED
Conditions: Osteoporosis
Interventions: DRUG: Placebo|DRUG: estradiol valerate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Bimatoprost for the Treatment of Eyebrow Hypotrichosis
Status: COMPLETED
Conditions: Eyebrow Hypotrichosis
Interventions: DRUG: bimatoprost solution|DRUG: Vehicle to bimatoprost solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Labial Frenulum Surgery - a Comparative Study of Conventional Scalpel and Er-Yag Laser Technique
Status: COMPLETED
Conditions: Labial Tie
Interventions: DEVICE: Scalpel|DEVICE: Er:YAG laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immune Response to Bivalent and Tetravalent Human Papillomavirus Vaccine in HIV Infected Adults
Status: COMPLETED
Conditions: HIV|Human Papillomavirus
Interventions: BIOLOGICAL: Gardasil|BIOLOGICAL: Cervarix
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Radiotherapy With Durvalumab Prior to Surgical Resection for HPV Negative Squamous Cell Carcinoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Squamous Cell Carcinoma of the Head and Neck
Interventions: DRUG: Durvalumab|RADIATION: Stereotactic Body Radiation Therapy (SBRT)|PROCEDURE: Standard of Care Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of NMES for Reducing Pain and Improving Functional Outcomes in Knee OA Patients
Status: COMPLETED
Conditions: Knee Osteoarthritis|Knee Pain Chronic|Knee Arthritis
Interventions: DEVICE: Active NMES
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Bepotastine Besilate Ophthalmic Solution in Allergic Conjunctivitis
Status: COMPLETED
Conditions: Allergic Conjunctivitis
Interventions: DRUG: Bepreve (bepotastine besilate ophthalmic solution) 1.5%|DRUG: placebo comparator|DRUG: Bepotastine Besilate Ophthalmic Solution 1.0%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Peppermint Oil During Screening Colonoscopy to Improve Visibility
Status: COMPLETED
Conditions: Enhancement of the ADR During Colonoscopy
Interventions: OTHER: Peppermint Oil|OTHER: Distilled water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Oral Abuse Potential Study of Nalbuphine
Status: COMPLETED
Conditions: Nalbuphine|Opioid Abuse
Interventions: DRUG: Nalbuphine HCl solution|DRUG: Placebo solution
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Effects of Lutein on Visual Function
Status: TERMINATED
Conditions: Healthy|Nutrition Poor
Interventions: DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: Lutein
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Long Term Safety Study of Tanezumab in Chronic Low Back Pain
Status: TERMINATED
Conditions: Low Back Pain
Interventions: BIOLOGICAL: Tanezumab 20 mg|BIOLOGICAL: Tanezumab 10 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: FMT for Patients With IBS With Fecal and Mucosal Microbiota Assessment
Status: COMPLETED
Conditions: Irritable Bowel Syndrome|Fecal Microbiota Transplantation
Interventions: PROCEDURE: Fecal Microbiota Transplantation|PROCEDURE: Sham|PROCEDURE: Fecal and Mucosal Microbiota Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Feasibility Study to Test the Acceptability, Tolerance and Safety of Incremental Haemodialysis
Status: COMPLETED
Conditions: Renal Failure|Hemodialysis Complication|Morality
Interventions: PROCEDURE: Incremental haemodialysis|PROCEDURE: Conventional haemodialysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vitamin D Effects on Prostate Pathology
Status: UNKNOWN
Conditions: Prostate Cancer
Interventions: DIETARY_SUPPLEMENT: vitamin D3 (cholecalciferol)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Enhancing Internet-delivered Cognitive Behaviour Therapy for Alcohol Misuse
Status: ACTIVE_NOT_RECRUITING
Conditions: Alcohol Misuse
Interventions: BEHAVIORAL: Self-Guided|BEHAVIORAL: Therapist-Guided
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Xpert Ultra and Xpert HIV-VL in People Living With HIV
Status: COMPLETED
Conditions: HIV/AIDS|TB - Tuberculosis|Antiretroviral Therapy, Highly Active
Interventions: DIAGNOSTIC_TEST: PLHIV Point of Care Xpert Ultra|DIAGNOSTIC_TEST: PLHIV Point of Care Xpert VL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study Examining Torcetrapib/Atorvastatin And Atorvastatin Effects On Clinical CV Events In Patients With Heart Disease
Status: TERMINATED
Conditions: Coronary Disease|Diabetes Mellitus
Interventions: DRUG: torcetrapib/atorvastatin|DRUG: atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Predictive Value of Cardiovascular Magnetic Resonance Related Parameters in STEMI Patients After Primary PCI for Adverse Left Ventricular Remodeling and Major Adverse Cardiovascular Events
Status: COMPLETED
Conditions: Cardiovascular Diseases
Interventions: DIAGNOSTIC_TEST: cardiovascular magnetic resonance (CMR)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Sitagliptin in Cystic Fibrosis-Related Diabetes
Status: TERMINATED
Conditions: Cystic Fibrosis
Interventions: DRUG: Sitagliptin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Study of Bacille Calmette Guerin (BCG) Delivery Via Disposable Syringe Jet Injector and Needle & Syringe
Status: COMPLETED
Conditions: Tuberculosis
Interventions: DEVICE: Bioject ID Pen|DEVICE: Needle and syringe
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Imaging Characteristics of a Follow-up 18F-AV-1451 Scan
Status: TERMINATED
Conditions: Alzheimer's Disease
Interventions: DRUG: Flortaucipir F18|DRUG: Florbetapir F 18|PROCEDURE: Brain PET Scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effect of 5 Times Dry Cupping in the Treatment of Chronic Neck Pain
Status: COMPLETED
Conditions: Neck Pain|Neck Pain Musculoskeletal|Mechanical/Motor Problems With Neck and Trunk
Interventions: PROCEDURE: Dry Cupping or fire cupping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Find Your PATHS (Pragmatic Assessment of a Tool to Help Survivors) to Sexual Health and Parenthood Study
Status: COMPLETED
Conditions: Cancer-related Problem/Condition|Sexuality|Fertility
Interventions: BEHAVIORAL: Online, interactive self-help program
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Capsulectomy vs Capsulotomy With Repair in Direct Anterior Total Hip Arthroplasty
Status: COMPLETED
Conditions: Hip Arthrosis|Osteoarthritis|Arthritis
Interventions: PROCEDURE: Capsulectomy in Direct Anterior Total Hip Arthroplasty|PROCEDURE: Capsulotomy in Direct Anterior Total Hip Arthroplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effects of Ezetimibe, Simvastatin, and Vytorin on Reducing L5 a Subfraction of LDL in Patients With Metabolic Syndrome.
Status: COMPLETED
Conditions: Metabolic Syndrome
Interventions: DRUG: Simvastatin|DRUG: Vytorin|DRUG: Placebo|DRUG: Ezetimibe
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Study To Evaluate The Effect Of Itraconazole On Pharmacokinetics Of PF-06463922 In Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: PF-06463922|DRUG: PF-06463922|DRUG: PF-06463922|DRUG: PF-06463922|DRUG: Itraconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Long-Term Effects of Insulin Plus Metformin Regimens on the Overall and Postprandial Glycemic Control of Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: premeal insulin lispro mixtures|DRUG: insulin glargine|DRUG: metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Bioequivalence Study of TAK-536 Pediatric Formulation
Status: COMPLETED
Conditions: Japanese Healthy Adult Males
Interventions: DRUG: TAK-536 Tablet|DRUG: TAK-536 Dry Syrup Formulation|DRUG: TAK-536 Ganule Formulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Study of Oral S-1 Plus Irinotecan in Patients With Advanced Gastric Cancer
Status: SUSPENDED
Conditions: Gastric Cancer
Interventions: DRUG: irinotecan|DRUG: S-1
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oro-tracheal Intubation: Flurbiprofen Subglottic Instillation to Prevent Laryngeal Inflammation
Status: UNKNOWN
Conditions: D010612
Interventions: DRUG: Flurbiprofen|DRUG: saline solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Long-term Safety Follow-up of Participants Exposed to the Candidate Ebola Vaccines Ad26.ZEBOV and/or MVA-BN-Filo
Status: TERMINATED
Conditions: Hemorrhagic Fever, Ebola
Interventions: BIOLOGICAL: Ad26.ZEBOV|BIOLOGICAL: MVA-BN-Filo
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Treatment of Traumatic Brain Injury (TBI)-Related Attention Deficits
Status: TERMINATED
Conditions: Traumatic Brain Injury|Attention Deficit Disorder
Interventions: DRUG: Vyvanse|PROCEDURE: fMRI|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Tattoo Particles: Picosecond Laser Versus Nanosecond Laser
Status: RECRUITING
Conditions: Tattoo; Pigmentation
Interventions: OTHER: picosecond laser treatment + measurement with a multiphoton tomography system|OTHER: nanosecond laser treatment + measurement with a multiphoton tomography system
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Early Termination of Empirical Antibiotics in Febrile Neutropenia in Children With Cancer
Status: UNKNOWN
Conditions: Neutropenia, Febrile|Pediatric Cancer
Interventions: OTHER: Early termination of empirical antibiotics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RESPONSE OF METABOLIC SYNDROME SEVERITY SCORE TO HIGH INTENISTY INTERVAL TRAINING IN WOMEN WITH CENTRAL OBESITY
Status: RECRUITING
Conditions: Metabolic Syndrom
Interventions: DEVICE: High intensity interval training|DIETARY_SUPPLEMENT: Caloric restricted diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Focal Radiotherapy Plus Low Dose Craniospinal Irradiation Followed by Adjuvant Chemotherapy in WNT Medulloblastoma.
Status: RECRUITING
Conditions: Medulloblastoma, WNT-activated
Interventions: RADIATION: Low dose Craniospinal Irradiation plus Focal Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Fx-1006A on Transthyretin Stabilization and Clinical Outcome Measures in Patients With Non-V30M Transthyretin Amyloidosis
Status: COMPLETED
Conditions: Transthyretin-associated Amyloidosis With Polyneuropathy
Interventions: DRUG: Fx-1006A
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Combination Chemotherapy Regimens in Treating Patients With Previously Untreated Aggressive Stage II, Stage III, or Stage IV Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: BIOLOGICAL: filgrastim|DRUG: cyclophosphamide|DRUG: doxorubicin hydrochloride|DRUG: etoposide|DRUG: prednisone|DRUG: vincristine sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Virtual Parent-led Support Group for Parents of Children and Youth With Eating Disorders: A Mixed Methods Feasibility Study Examining Acceptability, Cost and Parent Outcomes
Status: COMPLETED
Conditions: Eating Disorders
Interventions: BEHAVIORAL: Support Group for Caregivers
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Intrathecal Administration of Expanded Wharton's Jelly Mesenchymal Stem Cells in Chronic Traumatic Spinal Cord Injury
Status: COMPLETED
Conditions: Spinal Cord Injury, Chronic
Interventions: DRUG: XCEL-UMC-BETA|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating Safety, Tolerability, and Efficacy of Intravenous AP-SA02 in Subjects With S. Aureus Bacteremia
Status: RECRUITING
Conditions: Bacteremia|Staphylococcus Aureus|Staphylococcus Aureus Bacteremia|Bacteremia Staph|Bacteremia Due to Staphylococcus Aureus
Interventions: BIOLOGICAL: AP-SA02|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: EXTENSION - Long-term Follow-up Study of Patients Treated With AGN1 LOEP
Status: RECRUITING
Conditions: Osteoporosis
Interventions: OTHER: Clinical imaging is performed during the 24 and 60 month follow-up visits
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Venlafaxine 25 mg Tablets Under Fasting Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Venlafaxine 25 mg Tablets|DRUG: Effexor® 25 mg Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Compont - Varicose Veins of the Lower Extremities
Status: ACTIVE_NOT_RECRUITING
Conditions: Varicose Veins of Lower Limb
Interventions: DEVICE: Medical Adhesive|DEVICE: ClosureFast Endovenous Radiofrequency Ablation(RFA) Catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open Versus Arthroscopic Stabilization of Shoulder Instability With Subcritical Bone Loss: The OASIS Trial
Status: RECRUITING
Conditions: Shoulder Dislocation|Glenohumeral Dislocation|Anterior Shoulder Dislocation
Interventions: PROCEDURE: Arthroscopic Bankart repair procedure|PROCEDURE: Open Bankart|PROCEDURE: Latarjet|OTHER: Post-Operative Rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Remission of Lumbar Disc Herniation by Physiotherapy
Status: COMPLETED
Conditions: Lumbar Disc Herniation
Interventions: DEVICE: DRX 9000, Axiom Worldwide, Tampa, Florida|OTHER: physiotherapy|OTHER: spinal stabilization exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MultiStem® for Treatment of Trauma Induced Multiple Organ Failure/Systemic Inflammatory Response Syndrome
Status: RECRUITING
Conditions: Trauma|Adult Stem Cells
Interventions: BIOLOGICAL: MultiStem|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Safety, Pharmacokinetics, and Efficacy of Baloxavir Marboxil in Healthy Pediatric Participants From Birth to < 1 Year With Influenza-Like Symptoms
Status: COMPLETED
Conditions: Influenza
Interventions: DRUG: Baloxavir Marboxil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Cyclosporine and Remote Ischemic Preconditioning in Reperfusion Ischemia Injury on Tetralogy Fallot Patients With Correction Surgery
Status: COMPLETED
Conditions: Myocardial Injury|Cardiac Surgery
Interventions: DRUG: Cyclosporin|PROCEDURE: remote ischemic preconditioning|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Metformin as RenoProtector of Progressive Kidney Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Kidney Diseases
Interventions: DRUG: Metformin Hydrochloride|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Polyglycan Superparamagnetic Ferric Oxide Injection on Cardiovascular Magnetic Resonance Imaging
Status: RECRUITING
Conditions: Magnetic Resonance Imaging|Chronic Kidney Diseases
Interventions: DIAGNOSTIC_TEST: Polysaccharide superparamagnetic ferric oxide injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Freeze-dried Live Attenuated Measles/Rubella Combined Vaccine (Schwarz FF-8 Strain/TO-336 Strain) Specified Drug-use Survey of Vaccinees After the Second Vaccination
Status: COMPLETED
Conditions: Measles/Rubella
Interventions: DRUG: Freeze-dried live attenuated measles and rubella combined vaccine (Schwarz FF-8 strain/TO-336 strain)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Quantification of Upper Trapezius Muscle Stiffness Using Supersonic Shear Wave Imaging: Efficacy of Workplace-based Exercise Programme to Reduce Neck and Shoulder Disorders in Working Population
Status: UNKNOWN
Conditions: Neck Pain|Shoulder Pain
Interventions: OTHER: Workplace-based exercise|OTHER: Ergonomic advice and education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mechanisms for Vascular Dysfunction and Exercise Tolerance in CF
Status: ACTIVE_NOT_RECRUITING
Conditions: Cystic Fibrosis
Interventions: DIETARY_SUPPLEMENT: Acute Antioxidant|DIETARY_SUPPLEMENT: Chronic Antioxidant|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Distress Related to the Feeling of Loss of Dignity in Patients With Rheumatic Diseases
Status: UNKNOWN
Conditions: Rheumatic Diseases|Dignity|Quality of Life|Distress, Emotional
Interventions: OTHER: The Patient Dignity Inventory instrument (PDI)|OTHER: WHOQOL-BREF (quality of life) instrument
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase Ib Study of Humanized Anti-VEGF Monoclonal Antibody (Sevacizumab) Injection Plus FOLFIRI in Chinese Patients With Metastatic Colorectal Cancer
Status: UNKNOWN
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: Sevacizumab|DRUG: Irinotecan|DRUG: 5-FU|DRUG: Leucovorin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Online Large-group One-session Treatment for Public Speaking Anxiety
Status: COMPLETED
Conditions: Anxiety, Social
Interventions: BEHAVIORAL: Online large-group one-session treatment with post-treatment exercise targeting expectancy violation|BEHAVIORAL: Online large-group one-session treatment with post-treatment control exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Postoperative Analgesic Effects of Ibuprofen Versus Ketorolac in Patients Undergoing in Orthopedic Surgery
Status: COMPLETED
Conditions: Intravenous Drug Usage|Ibuprofen|Ketorolac|Knee Arthroscopy|Postoperative Pain
Interventions: DRUG: Ibuprofen 800 mg|DRUG: Ketorolac Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Investigation of the Efficacy and Safety of Drotrecogin Alfa (Activated) in Pediatric Severe Sepsis
Status: COMPLETED
Conditions: Sepsis
Interventions: DRUG: Drotrecogin alfa (activated)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pathophysiological Study of the Increase in Pancreatic Volume in Type 2 Diabetes Treatments.
Status: TERMINATED
Conditions: Type 2 Diabetes|Incretinomimetics|Pancreas
Interventions: DRUG: Incretinomimetics|DRUG: DPP-4 inhibitors
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Does Intraoperative Intravenous Iron Enhance Postoperative Oxygenation Profile in Total Knee Arthroplasty Surgery?
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DRUG: ferric carboxymaltose 1000 mg|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Diclofenac vs Dexamethasone in Combined Surgery
Status: COMPLETED
Conditions: Glaucoma|Cataract
Interventions: DRUG: diclofenac drops|DRUG: dexamethasone sodium phosphate 0.1% eye drops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Compair Efficacy of iv Dexmedetomidine & Tramadol for Post Spinal Shivering in Obs Patients Undergoing Cesarean Section
Status: NOT_YET_RECRUITING
Conditions: Post Spinal Shivering
Interventions: DRUG: Dexmedetomidine injection|DRUG: Tramadol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Determining Reactogenicity and Immunogenicity of Delayed COVID-19 Vaccine Schedule in Children
Status: UNKNOWN
Conditions: Vaccine Reaction|COVID-19|Children, Only
Interventions: BIOLOGICAL: BNT162b2 Pfizer-BioNTech/Comirnaty
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effect of Systane Ultra Lubricant Eye Drops (FID 112903) on Visual Performance
Status: COMPLETED
Conditions: Dry Eye
Interventions: OTHER: Systane Ultra Lubricant Eye Drops|OTHER: Optive Lubricant Eye Drops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Network-targeted Theta-burst Stimulation for Episodic Memory Improvement in Mild Cognitive Impairment
Status: RECRUITING
Conditions: Cognitive Dysfunction|Memory Disorders in Old Age
Interventions: DEVICE: Active Theta Burst Stimulation|DEVICE: Sham Theta Burst Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Adapted Home-based Exercise Program "T&E" (Test-and-Exercise) in Persons With Alzheimer's Disease (HOPE Trial)
Status: UNKNOWN
Conditions: Alzheimer Disease, Early Onset
Interventions: OTHER: Test and exercise home-based program
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PDL and Fractional Photothermolysis for Postsurgical Scars
Status: ENROLLING_BY_INVITATION
Conditions: Scar
Interventions: DEVICE: PDL (Pulsed Dye Laser)|DEVICE: Fractional Photothermolysis Laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Ultrasonic Scissors and Diathermy for Axillary Clearance in Breast Cancer Patients
Status: RECRUITING
Conditions: Seroma
Interventions: PROCEDURE: Axillary clearance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Open Appendectomy Versus Laparoscopic Appendectomy
Status: COMPLETED
Conditions: Appendicitis
Interventions: PROCEDURE: Open appendectomy|PROCEDURE: Laparoscopic appendectomy with metal endoclips|PROCEDURE: Laparoscopic appendectomy with suture ligation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Photobiomodulation Therapy for the Treatment of Lower Extremity Stress Fractures in a Military Training Setting
Status: RECRUITING
Conditions: Metatarsal Stress Fracture|Stress Fracture of Tibia
Interventions: DEVICE: Photobiomodulation Therapy with Standard Physical Therapy|OTHER: Sham Photobiomodulation Therapy with Standard Physical Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Double- Versus Single-balloon Enteroscopy for Obscure Small-bowel Bleeding
Status: UNKNOWN
Conditions: Small-Bowel Disorders
Interventions: PROCEDURE: Double-balloon enteroscopy|PROCEDURE: Single-balloon enteroscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety and Efficacy Study of rEV131 in the Treatment of Ocular Inflammation After Cataract Surgery
Status: UNKNOWN
Conditions: Ocular Inflammation
Interventions: DRUG: rEV131|DRUG: Prenisolone sodium phosphate 1.0%|DRUG: rEV131 vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose:
Clinical trial: Ambulatory Continuous Peripheral Nerve Blocks for Treatment of Post-Amputation Phantom Limb and Stump Pain
Status: COMPLETED
Conditions: Amputation|Phantom Limb|Stump Pain
Interventions: PROCEDURE: perineural ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of an Artificial-pancreas-like Learning-based Control in Type 1 Diabetes on Multiple Daily Injection Therapy
Status: NOT_YET_RECRUITING
Conditions: Diabetes Mellitus, Type 1
Interventions: DEVICE: AP-A Dosage Decision Support System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety, Tolerability, and Efficacy of SAGE-217 Compared to Placebo in Adult Participants With Comorbid Major Depressive Disorder (MDD) and Insomnia
Status: TERMINATED
Conditions: Major Depressive Disorder|Insomnia
Interventions: DRUG: SAGE-217|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Endoscopic Ultrasound-Guided Portosystemic Pressure Gradient Measurements
Status: COMPLETED
Conditions: Liver Cirrhosis|Liver Diseases|Hypertension, Portal
Interventions: DEVICE: EchoTip® Insight™ Portosystemic Pressure Gradient Measurement System (EchoTip® Insight™)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy Study of Strattera for Treating Attention Disorders in Traumatic Brain Injury (TBI)
Status: COMPLETED
Conditions: Traumatic Brain INjury
Interventions: DRUG: atomoxetine|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Etoricoxib for Routine Post-operative Pain Prophylaxis in Laparoscopic Surgery
Status: COMPLETED
Conditions: Hysterectomy|Tubal Excision|Ovariectomy|Postoperative Pain
Interventions: DRUG: etoricoxib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: To Investigate Effects of a New Infant Formula in Healthy Term Chinese Infants
Status: COMPLETED
Conditions: Healthy Infants
Interventions: DIETARY_SUPPLEMENT: New infant formula with synbiotics|DIETARY_SUPPLEMENT: Standard infant formula with prebiotics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Dexmedetomidine in Splanchnic Nerve Neurolysis
Status: COMPLETED
Conditions: Dexmedetomidine
Interventions: DRUG: Group 1|DRUG: Group 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy, Safety And Toleration Of CP-866,087 In Pre-Menopausal Women With Female Sexual Arousal Disorder.
Status: COMPLETED
Conditions: Sexual Dysfunction, Physiological
Interventions: DRUG: CP-866,087|DRUG: CP-866,087|DRUG: CP-866,087|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dose Escalation Study to Evaluate Safety and Tolerability of an Allogeneic Tumor Vaccine BIWB 2 in Patients With Advanced Malignant Melanoma
Status: COMPLETED
Conditions: Melanoma
Interventions: BIOLOGICAL: BIBW2 component A|BIOLOGICAL: BIBW2 component B
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety And Efficacy Of Xalatan Delivered Using Either A Conventional Dropper Bottle or A Delivery Device
Status: WITHDRAWN
Conditions: Glaucoma, Open-Angle|Ocular Hypertension
Interventions: DRUG: Xalatan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: A Pharmacokinetic Study Comparing PF-05280014 And Trastuzumab In Healthy Male Volunteers (REFLECTIONS B327-01)
Status: COMPLETED
Conditions: Healthy
Interventions: BIOLOGICAL: PF-05280014|BIOLOGICAL: Herceptin|BIOLOGICAL: Herceptin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Influence of Opioid Use on the Effects of Spinal Manipulative Therapy for Low Back Pain
Status: TERMINATED
Conditions: Low Back Pain|Opioid Use
Interventions: BEHAVIORAL: SMT|BEHAVIORAL: Activation Exercises|BEHAVIORAL: Mobilizing Exercises|BEHAVIORAL: Extended SMT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Decitabine and Gemcitabine for Pancreatic Cancer and Sarcoma
Status: COMPLETED
Conditions: Pancreatic Ductal Adenocarcinoma|Sarcoma
Interventions: DRUG: Decitabine|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Identification of a New Blood Biomarker for the Diagnosis and Prognosis of Liposarcomas
Status: RECRUITING
Conditions: Liposarcoma|Atypical Lipomatous Tumor
Interventions: DIAGNOSTIC_TEST: Blood sampling
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Progesterone Primed Endometrial Protocol Versus Gonadotropin-releasing Hormone Antagonist Protocol in Assisted Reproductive Treatments
Status: COMPLETED
Conditions: Progesterone Primed Endometrial Protocol|Gonadotropin Releasing Hormone Antagonist Protocol|Assisted Reproductive Treatments
Interventions: OTHER: Progesterone primed endometrial protocol|OTHER: Gonadotropin-releasing hormone antagonist protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low Versus High-Intensity Aerobic Training in Community-dwelling Older Men With Post-COVID 19 (SARS-CoV-2) Sarcopenia
Status: COMPLETED
Conditions: Sarcopenia
Interventions: OTHER: low-intensity aerobic training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Pursed-lips Breathing Combined With Aerobic Walking Exercise on Oxygenation and Activity Endurance in Lung Cancer Patients After Lobectomy
Status: COMPLETED
Conditions: Complications During Rehabilitation Stay
Interventions: BEHAVIORAL: pursing- lip breathing combined with aerobic walking exercise|BEHAVIORAL: pursing- lip breathing|BEHAVIORAL: aerobic walking exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Combined Volitional and Reactive Step Training in Reducing Falls Risk in Older Fallers
Status: RECRUITING
Conditions: Older Adults With a History of Falls
Interventions: BEHAVIORAL: Exercise|BEHAVIORAL: Active Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Prospective Multicenter Study for the Endovascular Treatment of Iliac Aneurysm With the Branched E-liac Stent Graft
Status: ACTIVE_NOT_RECRUITING
Conditions: Iliac Aneurysm|AAA
Interventions: DEVICE: Endovascular aorto-iliac repair
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Laser Assisted Sperm Selection of Viable Immotile Testicular Sperm in Azoospermic Infertile Men
Status: COMPLETED
Conditions: Azoospermia|IVF
Interventions: DEVICE: Laser Assisted Immotile Sperm Selection|PROCEDURE: Hypo-osmotic Swelling Test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: This Study is to Evaluate the Safety and Pharmacokinetics of SBS-101 in Patients With Oral Premalignant Lesions
Status: WITHDRAWN
Conditions: Leukoplakia, Oral
Interventions: DRUG: SBS-101|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Greater Occipital Nerve Block Value in Management of Postdural Puncture Headache
Status: COMPLETED
Conditions: Postdural Puncture Headache
Interventions: PROCEDURE: Greater Occipital Nerve Block|PROCEDURE: Bilateral suboccipital intramuscular injection|PROCEDURE: Epidural Blood Patch|DRUG: Normal Saline 10 mL Injection|DRUG: Lidocaine 2% Injectable Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Trial to Assess the Immunogenicity and Safety of the Trivalent Virosomal Influenza Vaccine, Formulation of 2012-2013, in Healthy Subjects Aged Over 3 Years Old to 18 Years Old
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: AdimFlu-V
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: BreEStim for Motor Recovery in Chronic Stroke With Severe Impairment (Pilot)
Status: NOT_YET_RECRUITING
Conditions: Motor Recovery
Interventions: DEVICE: BreEStim|DEVICE: EStim
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Trapeziometacarpal Prosthesis vs. Resection-Interposition Arthroplasty
Status: UNKNOWN
Conditions: Arthropathy of Hand
Interventions: PROCEDURE: Epping resection arthroplasty|PROCEDURE: CMC I prosthesis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Taxotere, Cisplatin and Irinotecan (CPT-11) for Esophagogastric Cancer
Status: COMPLETED
Conditions: Esophageal Cancer|Gastric Cancer|GE Junction Cancer
Interventions: DRUG: Taxotere|DRUG: Cisplatin|DRUG: Irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial Comparing Deep Versus Moderate Neuromuscular Block - in Low Pressure Pneumoperitoneum
Status: COMPLETED
Conditions: Nephrostomy; Complications|Pneumoperitoneum|Observation of Neuromuscular Block
Interventions: OTHER: Deep neuromsucular block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ticagrelor Therapy for RefrACTORy Migraine Study
Status: COMPLETED
Conditions: Migraine|Headache|Migraine Headache
Interventions: DRUG: Ticagrelor 90 mg twice per day
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Role and Mechanism of Probiotics in Improving Motor Symptoms in Mild to Moderate Parkinson's Disease
Status: RECRUITING
Conditions: Parkinson Disease|Parkinsonian Disorders|Basal Ganglia Diseases|Brain Diseases|Movement Disorders|Neurodegenerative Diseases|Central Nervous System Diseases|Nervous System Diseases
Interventions: DRUG: Live Combined Bifidobacterium,Lactobacillus and Enterococcus Capsules|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prevalence of Sleep Apnea in Patients Undergoing Surgery for Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer|Sleep Apnea Syndromes|Hypoxia
Interventions: PROCEDURE: Open surgery for colorectal cancer|PROCEDURE: Laparoscopic or robotic surgery
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Transport Distraction Osteogenesis for Ramus-Condyle Unit
Status: COMPLETED
Conditions: Bilateral or Unilateral Deficient Ramus-condyle Unit
Interventions: DEVICE: Distraction Osteogenesis for Reconstruction of Ramus-Condyle
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Metformin Plus Irinotecan for Refractory Colorectal Cancer
Status: UNKNOWN
Conditions: Colorectal Neoplasms|Adenocarcinoma
Interventions: DRUG: metformin|DRUG: irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Observation, Radiation Therapy, Combination Chemotherapy, and/or Surgery in Treating Young Patients With Soft Tissue Sarcoma
Status: COMPLETED
Conditions: Adult Alveolar Soft-part Sarcoma|Adult Angiosarcoma|Adult Epithelioid Sarcoma|Adult Extraskeletal Chondrosarcoma|Adult Extraskeletal Osteosarcoma|Adult Fibrosarcoma|Adult Leiomyosarcoma|Adult Liposarcoma|Adult Malignant Fibrous Histiocytoma|Adult Malignant Hemangiopericytoma|Adult Malignant Mesenchymoma|Adult Neurofibrosarcoma|Adult Synovial Sarcoma|Childhood Alveolar Soft-part Sarcoma|Childhood Angiosarcoma|Childhood Epithelioid Sarcoma|Childhood Fibrosarcoma|Childhood Leiomyosarcoma|Childhood Liposarcoma|Childhood Malignant Mesenchymoma|Childhood Neurofibrosarcoma|Childhood Synovial Sarcoma|Dermatofibrosarcoma Protuberans|Metastatic Childhood Soft Tissue Sarcoma|Nonmetastatic Childhood Soft Tissue Sarcoma|Stage I Adult Soft Tissue Sarcoma|Stage II Adult Soft Tissue Sarcoma|Stage III Adult Soft Tissue Sarcoma|Stage IV Adult Soft Tissue Sarcoma
Interventions: DRUG: doxorubicin hydrochloride|OTHER: clinical observation|PROCEDURE: therapeutic conventional surgery|RADIATION: 3-dimensional conformal radiation therapy|DRUG: ifosfamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Study Matching Intraperitoneal Onlay Mesh (IPOM) and Sublay Mesh to Treat Umbilical Hernia
Status: TERMINATED
Conditions: Umbilical Hernia
Interventions: PROCEDURE: intraperitoneal onlay mesh repair|PROCEDURE: sublay mesh repair
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reconstruction Of Acute Coracoclavicular Ligament Disruption With and Without Tendon Graft
Status: UNKNOWN
Conditions: Acromioclavicular Joint Dislocation
Interventions: PROCEDURE: tendon graft|OTHER: No intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Phase II Study to Evaluate G17DT in Combination With Irinotecan in Patients With Colorectal Carcinoma
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: BIOLOGICAL: G17DT-Irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Questionnaires in Identifying Upper Extremity Function and Quality of Life After Treatment in Patients With Breast Cancer
Status: TERMINATED
Conditions: Musculoskeletal Complication|Recurrent Breast Carcinoma|Stage IA Breast Cancer|Stage IB Breast Cancer|Stage IIA Breast Cancer|Stage IIB Breast Cancer|Stage IIIA Breast Cancer|Stage IIIB Breast Cancer|Stage IIIC Breast Cancer|Stage IV Breast Cancer|Therapy-Related Toxicity
Interventions: PROCEDURE: Quality-of-Life Assessment|OTHER: Questionnaire Administration|OTHER: Medical Chart Review
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Treatment of Post-Surgical Scars With Traditional Ablative Er:YAG Versus Fractional Ablative Er:YAG
Status: COMPLETED
Conditions: Post-Surgical Scars
Interventions: DEVICE: Er:YAG laser, traditional and fractional settings
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Exploratory Maintenance Trial of BI 655064 in Patients With Lupus Nephritis
Status: COMPLETED
Conditions: Lupus Nephritis
Interventions: DRUG: BI 655064|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Thalidomide Combined With Chemotherapy in the Treatment of Relapsed or Refractory Yolk Sac Tumor
Status: COMPLETED
Conditions: Germ Cell Tumor|Yolk Sac Tumor
Interventions: DRUG: Thalidomide combined with TGA chemotherapy (nab-paclitaxel + gemcitabine+ epirubicin)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Artificial Saliva Containing Cumin and Ginger Extract in Head and Neck Cancer Patients With Xerostomia
Status: NOT_YET_RECRUITING
Conditions: Xerostomia
Interventions: OTHER: Artificial saliva containing cumin and ginger extract|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility of Intraoperative Microdialysis During Neurosurgery for Central Nervous System Malignancies
Status: RECRUITING
Conditions: Anaplastic Astrocytoma|Anaplastic Oligodendroglioma|Diffuse Astrocytoma|Diffuse Glioma|Glioblastoma|Metastatic Malignant Neoplasm in the Brain|Oligodendroglioma
Interventions: PROCEDURE: Microdialysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Bacteriophage Therapy in Tonsillitis
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Tonsillitis
Interventions: DRUG: Nebulizer inhalation irrigation of the mucous membranes of the tonsils with a bacteriophage.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE