pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Multicenter, Double-blind, Randomized, Placebo-controlled, Parallel Group Trial to Investigate the Efficacy and Safety of SPM 927 (200mg/Day and 400mg/Day) as Adjunctive Therapy in Subjects With Partial Seizures With or Without Secondary Generalization
Status: COMPLETED
Conditions: Partial Seizures With or Without Secondary Generalization
Interventions: DRUG: SPM 927
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Randomized, Double-Blind Study of MKC-442 Combined With Viracept in Patients Who Are Epivir + Retrovir Experienced and Are Protease Inhibitor- and Non-Nucleoside Reverse Transcriptase Inhibitor-Naive
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Emivirine|DRUG: Nelfinavir mesylate
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Oral Sweet Solution to Prevent Pain During Neonatal Hip Examination
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Sterile water|DRUG: 30% glucose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy, Radiation Therapy, and Vaccine Therapy With Basiliximab in Treating Patients With Glioblastoma Multiforme That Has Been Removed by Surgery
Status: COMPLETED
Conditions: Malignant Neoplasms of Brain
Interventions: BIOLOGICAL: PEP-3-KLH conjugate vaccine|BIOLOGICAL: daclizumab|DRUG: temozolomide|OTHER: placebo|BIOLOGICAL: PEP-3-KLH
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intravenous Tranexamic Acid Versus IV Carbetocin in Abdominal Myomectomy
Status: UNKNOWN
Conditions: Myomectomy
Interventions: DRUG: intravenous tranexamic acid|DRUG: intravenous carbetocin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study to Assess the Efficacy, Safety and Tolerability of Secukinumab in Japanese Subjects With Generalized Pustular Psoriasis (GPP)
Status: COMPLETED
Conditions: Psoriasis
Interventions: BIOLOGICAL: Secukinumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: AMPLEX Ankle Fusion and Hindfoot
Status: COMPLETED
Conditions: Arthrodesis Surgery Involving the Hindfoot or Ankle
Interventions: DEVICE: AMPLEX|PROCEDURE: Autogenous Bone Graft (ABG)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Chemoradiation Plus PD-1 Antibody(SHR-1210) in Locally Advanced Proximal Stomach Adenocarcinoma
Status: UNKNOWN
Conditions: Gastric Adenocarcinoma
Interventions: DRUG: Neoadjuvant chemoradiation plus PD-1 antibody(SHR-1210)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diagnostic Yield of FNA Needle and FNB Needle for Autoimmune Pancreatitis
Status: UNKNOWN
Conditions: Autoimmune Pancreatitis
Interventions: DEVICE: 19G FNA needle|DEVICE: 20G FNB needle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Investigator Initiated Trial to Study Duobrii® Lotion in the Treatment of Mild Plaque Psoriasis in Adults
Status: COMPLETED
Conditions: Plaque Psoriasis
Interventions: DRUG: Duobrii 0.01 % / 0.045 % Topical Lotion|DRUG: CeraVe, Topical Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hydroxychloroquine Chemoprophylaxis in Healthcare Personnel in Contact With COVID-19 Patients (PHYDRA Trial)
Status: COMPLETED
Conditions: COVID-19|Severe Acute Respiratory Syndrome
Interventions: DRUG: Hydroxychloroquine|DRUG: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Intraoperative Dexmedetomidine on Postoperative Morphine Requirements After Breast Cancer Surgery
Status: RECRUITING
Conditions: Morphine Consumption
Interventions: DRUG: Dexmedetomidine|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Assess the Levels in Blood Plasma of BMS-986278 in Healthy Participants Following Administration of Tablets, With or Without Food, and in the Presence of an Antacid (Esomeprazole)
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DRUG: BMS-986278 Tablet|DRUG: Esomeprazole|DRUG: BMS-986278 suspension
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Laparoscopic or Conventional Mesh Repair of Incisional and Umbilical Hernia
Status: TERMINATED
Conditions: Incisional Hernia|Umbilical Hernia
Interventions: PROCEDURE: Laparoscopic mesh hernia repair|PROCEDURE: Open anterior approach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Observational Study of Patients Treated With Nivolumab and Chemotherapy for Advanced or Metastatic Esophageal, Gastroesophageal or Gastric Cancer in France
Status: NOT_YET_RECRUITING
Conditions: Gastric Adenocarcinoma|Gastro-esophageal Junction Adenocarcinoma|Esophageal Adenocarcinoma (EAC)|Esophageal Squamous Cell Carcinoma (ESCC)
Interventions: DRUG: nivolumab + chemotherapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Pharmacokinetics of ASA404 When Given Together With Fluvoxamine, a Selective Serotonin Receptor Reuptake Inhibitor and CYP1A2 Inhibitor
Status: TERMINATED
Conditions: Solid Tumors
Interventions: DRUG: Vadimezan™
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adding Polyphenol-rich Pulses to Daily Diet Improves Skin Health by Reshaping the Skin Microbiome
Status: NOT_YET_RECRUITING
Conditions: Healthy
Interventions: OTHER: Pulse Diet|OTHER: Control Rice Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 3 Immunogenicity and Safety Study of an Inactivated H5N1 Influenza Vaccine (Whole Virion, Vero Cell Derived)
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Whole virion, Vero cell-derived influenza vaccine containing H5N1 HA antigen|BIOLOGICAL: Whole virion, Vero cell-derived influenza vaccine containing H5N1 HA antigen|BIOLOGICAL: Whole virion, Vero cell-derived influenza vaccine containing H5N1 HA antigen|BIOLOGICAL: Whole virion, Vero cell-derived influenza vaccine containing H5N1 HA antigen|BIOLOGICAL: Whole virion, Vero cell-derived influenza vaccine containing H5N1 HA antigen|BIOLOGICAL: Whole virion, Vero cell-derived influenza vaccine containing H5N1 HA antigen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Acute Caffeine Ingestion on Futsal Performance
Status: COMPLETED
Conditions: Caffeine|Placebo
Interventions: DIETARY_SUPPLEMENT: Caffeine|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intra-operative Use of Indigo Carmine Dye for the Delineation of Ill Defined Tumor Borders Using Stereotactic Injection
Status: COMPLETED
Conditions: Brain Tumors With Ill-defined Margins
Interventions: DRUG: Indigo carmine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Aleglitazar in Combination With Metformin in Patients With Type 2 Diabetes Mellitus Who Are Inadequately Controlled With Metformin Monotherapy
Status: COMPLETED
Conditions: Diabetes Mellitus Type 2
Interventions: DRUG: aleglitazar|DRUG: metformin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Opioid Titration in the Hospice Setting: Barriers Assessment and Modification of the Model Order Sheet and Protocol
Status: COMPLETED
Conditions: Cancer Pain
Interventions: OTHER: Individual patient interview, focus group and structured survey|OTHER: interview, focus group and structured survey|OTHER: interview, focus group and structured survey|OTHER: interview, focus group and structured survey
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Calcium Supplementation for a Healthy Weight (CaSHeW)
Status: COMPLETED
Conditions: Obesity|Overweight
Interventions: DIETARY_SUPPLEMENT: Orange Juice fortified with Calcium and Vitamin D|DIETARY_SUPPLEMENT: Orange juice without Ca or VitD|BEHAVIORAL: Nutritional Counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Surgery With or Without Combination Chemotherapy in Treating Patients With Stomach Cancer
Status: COMPLETED
Conditions: Gastric Cancer
Interventions: DRUG: cisplatin|DRUG: epirubicin hydrochloride|DRUG: fluorouracil|PROCEDURE: conventional surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Effects of Transcutaneous Auricular Vagus Nerve Stimulation on Obesity and Insulin Resistance
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Obesity
Interventions: DEVICE: taVNS|DEVICE: Sham taVNS
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Brain Activity Under the Influence of JWH
Status: NOT_YET_RECRUITING
Conditions: Neurotransmission During JWH Intoxication
Interventions: DRUG: JWH018|OTHER: non-active control (no substance)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: rTMS Study in Depression to Evaluate the Relationship Between Brain Plasticity and Clinical Outcome
Status: WITHDRAWN
Conditions: Major Depressive Disorder
Interventions: DEVICE: TMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Immediate Axillary Plasty With a Pedicled Muscle Flap for Breast Cancer Related Lymphedema Prevention
Status: UNKNOWN
Conditions: Lymphedema|Breast Neoplasm
Interventions: PROCEDURE: Immediate Axillary Plasty
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Nasal Gel for the Prevention and Treatment of Nausea Associated With Motion Sickness
Status: COMPLETED
Conditions: Motion Sickness
Interventions: DRUG: DPI-386 Nasal Gel|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Exercise Programs in Healthy Young Women at Increased Risk of Developing Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer|Healthy, no Evidence of Disease
Interventions: BEHAVIORAL: exercise intervention|OTHER: counseling intervention|OTHER: gas chromatography|OTHER: immunoenzyme technique|OTHER: immunologic technique|OTHER: laboratory biomarker analysis|OTHER: mass spectrometry|OTHER: physiologic testing|OTHER: questionnaire administration|OTHER: survey administration|PROCEDURE: dual x-ray absorptometry|PROCEDURE: magnetic resonance imaging|PROCEDURE: study of high risk factors
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE|Primary Purpose: OTHER
Clinical trial: Drug-Induced Sleep Endoscopy for the Optimisation of Treatment of Patients With Obstruction Sleep Apnoea
Status: COMPLETED
Conditions: Obstructive Sleep Apnoea|Sleep-Disordered Breathing
Interventions: PROCEDURE: Short-time diagnostic anaesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Safety and Immunogenicity of Acellular Pertussis Vaccine in Bone Marrow Transplant Recipients
Status: UNKNOWN
Conditions: Pertussis
Interventions: BIOLOGICAL: Tetanus and Diphtheria Toxoids Adsorbed Combined with Acellular Pertussis (Adacel)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Tolerance and Performance of Cyto-selective Difluoroethane-based Cryotherapy in the Treatment of Brown Spots.
Status: COMPLETED
Conditions: Solar Lentigo|Senile Lentigo|Post-inflammatory Hyperpigmentation
Interventions: DEVICE: Prototypes (816-v1 001) to (816-v1 050)|DEVICE: Prototype (816-v1 051) to (816-v1 100)|DEVICE: Prototypes (816-v1 101) to (816-v1 150)|DEVICE: Prototypes (816-v1 151) to (816-v1 200)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: KardiaMobile ECG Monitoring Effects on Health Care Utilization and Patient Experience With Atrial Fibrillation
Status: ENROLLING_BY_INVITATION
Conditions: Atrial Fibrillation (AF)
Interventions: OTHER: Kardia Mobile 6L Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study to Compare Oxybutynin to a Placebo in Women and the Effect on Plantar Hyperhidrosis
Status: COMPLETED
Conditions: Hyperhidrosis
Interventions: DRUG: Oxybutynin 5 mg pills
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The EFFECT Study: Probiotic and HMO Supplementation in Infants
Status: COMPLETED
Conditions: Infant Gut Microbiome
Interventions: OTHER: B. infantis EVC001|OTHER: Lacto-N-tetraose (LNT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: FishGastro Study: Fish Consumption and Gastro-Intestinal Health
Status: COMPLETED
Conditions: Colorectal Cancer|Ulcerative Colitis|Polyps
Interventions: BEHAVIORAL: Increased dietary intake of salmon or cod
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Ketamine Effect After Laparoscopic Gastric Reduction: A Randomized, Double-Blinded, Placebo Controlled Study
Status: COMPLETED
Conditions: Pain|Obesity|Hypoxia
Interventions: DRUG: Ketamine|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of the Clinical Effectiveness of Bioactive Glass (S53P4) in the Treatment of Tibia and Femur Non-unions
Status: UNKNOWN
Conditions: Pseudoarthrosis of Bone
Interventions: DEVICE: bioglass (S53P4)|DEVICE: RIA and TCP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Lenalidomide and R-CHOP in B-cell Lymphoma
Status: COMPLETED
Conditions: Lymphoma, Large B-Cell, Diffuse|Follicular Lymphoma|Mantle Cell Lymphoma|Marginal Zone Lymphoma
Interventions: DRUG: Lenalidomide and R-CHOP
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Magnesium Sulfate; Postoperative Nausea and Vomiting; Laparoscopic Surgery
Status: UNKNOWN
Conditions: Gynecologic Disease
Interventions: DRUG: Mg (magnesium sulfate)|DRUG: Control (saline)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluating Weight Loss Programs for Obese People at Risk for Heart Disease (The POWER Study)
Status: COMPLETED
Conditions: Obesity
Interventions: BEHAVIORAL: Call-Center Directed (CCD) Weight Loss Program|BEHAVIORAL: In-Person Directed (IPD) Weight Loss Program|BEHAVIORAL: Self-Directed Weight Loss Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Slow Back Stroke Massage and Murrotal Quran on Fatigue and Quality of Life of Patients Undergoing Haemodialysis
Status: UNKNOWN
Conditions: Fatigue; Hemodialysis; Chronic Kidney Disease; Quality of Life
Interventions: OTHER: slow stroke massage and murrotal quran
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Immunogenicity and Safety of Meningococcal ACWY Conjugate Vaccine in Healthy Subjects From 2 to 75 Years of Age in India
Status: COMPLETED
Conditions: Bacterial Meningitis
Interventions: BIOLOGICAL: Meningococcal ACWY conjugate vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Diabeloop for Kids
Status: COMPLETED
Conditions: Closed Loop|Diabetes Mellitus, Type 1|Young Children (6 to 12 Years Old )
Interventions: DEVICE: Continuous Glucose Monitoring|DEVICE: External Insulin Pump|DEVICE: Diabeloop Software (Model predictive control)|OTHER: Remote monitoring (Telemedicine)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reactogenicity, Immunogenicity of Trivalent Influenza Vaccine With Recombinant Interferon Alpha Among Chronic Lymphocytic Leukemia
Status: WITHDRAWN
Conditions: Chronic Lymphocytic Leukemia
Interventions: BIOLOGICAL: Influenza Vaccine Trivalent Inactivated (TIV)|DRUG: Pegylated interferon (PEGrIFN-α, Pegasys)|DRUG: Interferon (IFNα, Roferon-A)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Warm-up Efficiency by Body Warmer Versus Standard Procedure in Severely Traumatized Patients
Status: COMPLETED
Conditions: Hypothermia|Trauma, Psychological
Interventions: DEVICE: Body warmer|DEVICE: Standard warming procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of People With HIV Infection Who Have High Viral Loads Despite Combination Antiretroviral Therapy
Status: COMPLETED
Conditions: Acquired Immune Deficiency Syndrome Virus|Acquired Immunodeficiency Syndrome Virus|AIDS Virus|Human Immunodeficiency Virus|Human Immunodeficiency Viruses
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Internet-based Depression Treatment: Differential Efficacy of Different Therapeutic Components
Status: UNKNOWN
Conditions: Depression
Interventions: BEHAVIORAL: Internet-based Global Protocol|BEHAVIORAL: Internet-based Behavioral Activation Protocol|BEHAVIORAL: Internet-based Positive Psychology Protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Leflunomide for the Treatment of Relapsed or Refractory CD30+ Lymphoproliferative Disorders
Status: COMPLETED
Conditions: Recurrent Lymphoproliferative Disorder|Refractory Lymphoproliferative Disorder
Interventions: DRUG: Leflunomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Feasibility Study of Dendritic Cell Vaccination for Newly Diagnosed Glioblastoma Multiforme
Status: COMPLETED
Conditions: Glioblastoma Multiforme
Interventions: BIOLOGICAL: Autologous Dendritic Cell|DRUG: Temozolomide|PROCEDURE: Radiotherapy|BIOLOGICAL: Dendritic Cell Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Palliative Lattice Stereotactic Body Radiotherapy (SBRT)
Status: COMPLETED
Conditions: Cancer|Palliative Radiotherapy
Interventions: RADIATION: Lattice stereotactic body radiation therapy|PROCEDURE: Peripheral blood
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Volinanserin and Lormetazepam in the Treatment of Insomnia Characterized by Sleep Maintenance Difficulties
Status: TERMINATED
Conditions: Sleep Initiation and Maintenance Disorders
Interventions: DRUG: Volinanserin (M100907)|DRUG: Lormetazepam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Photodynamic Therapy for Bile Duct Invasion of Hepatocellular Carcinoma
Status: COMPLETED
Conditions: Hepatocellular Carcinoma|Obstructive Jaundice
Interventions: DRUG: Photofrin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness and Cost Effectiveness of OkeyMind for Social Anxiety-Driven Depression Among Youth
Status: NOT_YET_RECRUITING
Conditions: Depression|Social Anxiety
Interventions: BEHAVIORAL: OkeyMind intervention|BEHAVIORAL: Wait-list control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Reduced Chemotherapy in Low Risk DLBCL
Status: ACTIVE_NOT_RECRUITING
Conditions: Diffuse Large B-cell Lymphoma
Interventions: DRUG: Rituximab|DRUG: Cyclophosphamide|DRUG: Epirubicin|DRUG: Vincristine|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Dextenza Insert in Upper vs Lower Punctum Following Cataract Surgery With PCIOL.
Status: COMPLETED
Conditions: Cataract
Interventions: DRUG: Dextenza 0.4Mg Ophthalmic Insert
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PET Fibrin Imaging of DVT and PE
Status: RECRUITING
Conditions: Pulmonary Embolism|Deep Vein Thrombosis|Venous Thromboembolism
Interventions: DRUG: 64Cu-FBP8|DIAGNOSTIC_TEST: PET-CT imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Single and Multiple Ascending Dose Study of Niclosamide in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Niclosamide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Vestibular Balance Therapy Intervention for Children
Status: RECRUITING
Conditions: Vestibulocochlear Nerve Diseases|Vestibular Disorder|Bilateral Vestibular Loss
Interventions: OTHER: Vestibular Balance Therapy|OTHER: Sham Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Contribution of Auriculotherapy in the Management of Mastectomy With Immediate Reconstruction by Latissimus Dorsi Flap (ATMAGD)
Status: TERMINATED
Conditions: Mastectomy|Auriculotherapy
Interventions: DRUG: Auriculotherapy|BEHAVIORAL: Chronic Post-Surgical Pain evaluation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Trial in Healthy Volunteers, to Evaluate the Tolerability and Cardiac Safety of Prucalopride
Status: COMPLETED
Conditions: Constipation
Interventions: DRUG: prucalopride|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: A Mobile Supportive Care App for Patients With Metastatic Lung Cancer
Status: UNKNOWN
Conditions: Nonsmall Cell Lung Cancer|Small Cell Lung Carcinoma
Interventions: OTHER: The Lung Cancer App - LuCApp|OTHER: Standard care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pioglitazone for the Treatment of Major Depressive Disorder Comorbid With Metabolic Syndrome
Status: COMPLETED
Conditions: Depressive Disorder, Major|Metabolic Syndrome X
Interventions: DRUG: Pioglitazone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exercise and Health Counseling in Pediatric Hematopoietic Stem Cell Transplantation
Status: RECRUITING
Conditions: Hematopoietic System--Cancer
Interventions: BEHAVIORAL: Control Group (Active Comparator)|BEHAVIORAL: Intervention Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Cryoprobe Transbronchial Lung Biopsy in Lung Transplant Patients
Status: COMPLETED
Conditions: Lung Transplantation
Interventions: PROCEDURE: Cryoprobe biopsy|PROCEDURE: Forceps Biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Specificity of Elevated Plasma EM66 Levels in Pheochromocytoma
Status: COMPLETED
Conditions: Pheochromocytoma|Paraganglioma|Essential Hypertension
Interventions: OTHER: plasma EM66 & CgA levels assessment|OTHER: usual follow up with regular EM66 & Cga levels assessment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Aromatherapy and Foot Massage on Happiness, Sleep Quality, and Fatigue Levels of Patients With Stroke
Status: COMPLETED
Conditions: Stroke, Ischemic
Interventions: OTHER: foot massage|OTHER: Foot massage +Aromatherapy group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Project PEAK: Early Intervention for ADHD
Status: RECRUITING
Conditions: Attention Deficit Hyperactivity Disorder|Parent-Child Relations|Child Behavior|Parenting
Interventions: BEHAVIORAL: Promoting Engagement with ADHD Pre-Kindergarteners
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sunitinib Plus Temsirolimus in Patients With Renal Cell Cancer (RCC)
Status: COMPLETED
Conditions: Renal Cell Cancer|Kidney Cancer
Interventions: DRUG: Sunitinib|DRUG: Temsirolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Clinical Non-inferiority of Actparin® (Laboratorio Bergamo) Compared to Heparin Sodium (APP Pharmaceuticals), in Patients With Chronic Renal Failure
Status: UNKNOWN
Conditions: Chronic Renal Failure
Interventions: BIOLOGICAL: heparin sodium|BIOLOGICAL: heparin sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of Dexamethasone Added to Ropivacaine and Ropivacaine Alone in Caudal Analgesia in Children Undergoing Orchiopexy
Status: COMPLETED
Conditions: Cryptorchidism
Interventions: PROCEDURE: Caudal block|PROCEDURE: Caudal block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: MITIGAAT: Multifaceted Intervention To Improve Graft Outcome Disparities in African American Kidney Transplants
Status: RECRUITING
Conditions: Medication Adherence|Medication Compliance
Interventions: OTHER: mHealth app/dashboard
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Comparison of the Analgesic Efficacy and Safety of Once Daily Tramadol OAD Tablets to Twice Daily Tramadol BID for the Treatment of Osteoarthritis of the Knee (Extension Protocol) and Open Label Safety Follow-Up
Status: COMPLETED
Conditions: Pain|Osteoarthritis, Knee
Interventions: DRUG: Tramadol OAD|DRUG: Tramadol OAD|DRUG: Tramadol OAD|DRUG: Tramadol OAD 100mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intubation During Pediatric Resuscitation
Status: UNKNOWN
Conditions: Cardiac Arrest|Endotracheal Intubation|Pediatric Manikin
Interventions: DEVICE: Miller Laryngoscope|DEVICE: The Berci-Kaplan DCI|DEVICE: The AirTraq|DEVICE: GlideScope GVL|DEVICE: The Pentax AWS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety, Reactogenicity and Immunogenicity of GlaxoSmithKline (GSK) Biologicals' Investigational Respiratory Syncytial Virus (RSV) Vaccines
Status: COMPLETED
Conditions: Infections, Respiratory Syncytial Virus
Interventions: BIOLOGICAL: RSV vaccine GSK3003892A (formulation 1)|BIOLOGICAL: RSV vaccine GSK3003893A (formulation 2)|BIOLOGICAL: RSV vaccine GSK3003895A (formulation 3)|BIOLOGICAL: RSV vaccine GSK3003896A (formulation 4)|BIOLOGICAL: RSV vaccine GSK3003898A (formulation 5)|BIOLOGICAL: RSV vaccine GSK3003899A (formulation 6)|DRUG: Placebo comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Treatment of Obsessive Compulsive Disorder in Children
Status: COMPLETED
Conditions: Obsessive-Compulsive Disorder
Interventions: DRUG: Serotonin reuptake inhibitors management|BEHAVIORAL: Cognitive behavioral therapy by a psychologist|BEHAVIORAL: Instructional cognitive behavioral therapy by a psychiatrist
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Apply tACS to Alleviate Anxiety Symptoms
Status: RECRUITING
Conditions: Anxiety Disorders
Interventions: DEVICE: transcranial alternating current stimulation (tACS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase Ⅱ Study of F520 in Patients With Urothelial Carcinoma
Status: UNKNOWN
Conditions: Locally Advanced or Metastatic Urothelial Cell Carcinoma
Interventions: DRUG: F520
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phenotype and Epidemiology of the Polycystic Ovary Syndrome (PCOS) in Colombia (PEP - Colombia) Study.
Status: RECRUITING
Conditions: Polycystic Ovary Syndrome|Hyperandrogenism|Endocrine System Diseases
Interventions: DIAGNOSTIC_TEST: Diagnostic Ultrasound|DIAGNOSTIC_TEST: Venous puncture
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Binocular Vision Anomalies After Cataract and Refractive Surgery
Status: COMPLETED
Conditions: Binocular Vision Disorder|Refractive Errors|Cataract
Interventions: PROCEDURE: cataract surgery|PROCEDURE: Corneal refractive surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparison of Pudendal Nerve Block and Caudal Block for Hypospadias in Young Children
Status: COMPLETED
Conditions: Hypospadias and Epispadias
Interventions: PROCEDURE: Caudal block|PROCEDURE: Bilateral Pudendal block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: tDCS(Transcranial Direct Current Stimulation) Efficacy in Bipolar Depression : RCT Study
Status: UNKNOWN
Conditions: tDCS
Interventions: DEVICE: ACTIVE|DEVICE: SHAM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: mHealth Biometrics for Young People With Obesity (MOTIVATE- LOOP)
Status: UNKNOWN
Conditions: Obesity, Adolescent
Interventions: BEHAVIORAL: LOOP + mHealth technology assisted exercise counselling|BEHAVIORAL: LOOP Only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Research of Pathological Imaging Diagnosis of Ocular Tumors Based on New Artificial Intelligence Algorithm
Status: UNKNOWN
Conditions: Melanoma (Skin)|Melanoma in Situ|Nevus Eye|Sebaceous Gland Carcinoma of the Eyelid|Basal Cell Carcinoma|Squamous Cell Carcinoma in Situ|Ocular Tumor
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Avoid FFS - Use of the Atrial Pacemaker Lead 1699 With Very Short Tip Ring Spacing to Avoid Far Field Sensing
Status: COMPLETED
Conditions: Atrial Fibrillation|Bradycardia
Interventions: DEVICE: pacemaker implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Assessment of Platelet Rich Fibrin Efficiency on Healing Delay and on Jawbone Osteochemonecrosis Provoked by Bisphosphonates
Status: COMPLETED
Conditions: Jawbone Osteochemonecrosis Induced by Bisphosphonates
Interventions: PROCEDURE: Bone curettage + PRF|PROCEDURE: Bone curettage alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Open-label Long Term (52 Weeks) Safety and Tolerability of Agomelatine Sublingual Tablets in Major Depressive Disorder (MDD)
Status: TERMINATED
Conditions: Major Depressive Disorder
Interventions: DRUG: AGO178|DRUG: AGO178
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Correlation Between the Amplitude of Ankle Dorsiflexion and Occurrence of Patellofemoral Pain Syndrome
Status: COMPLETED
Conditions: Patellofemoral Pain Syndrome
Interventions: DIAGNOSTIC_TEST: Ankle dorsiflexion measurement
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Medpulser Electroporation With Bleomycin Study to Treat Anterior Head and Neck Squamous Cell Carcinoma
Status: TERMINATED
Conditions: Head and Neck Cancer
Interventions: COMBINATION_PRODUCT: Medpulser electroporation with Bleomycin|PROCEDURE: Tumor surgical excision
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Carboplatin Plus Gemcitabine Followed by Concomitant Chemoradiation for Non-resectable Stage III NSCLC
Status: COMPLETED
Conditions: Non-Small-Cell-Lung Cancer
Interventions: DRUG: carboplatin/gemcitabine|PROCEDURE: cisplatin/radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Feasibility Study Using CLINIMACS® for Alpha/Beta T-Cell Depletion in Stem Cell Transplant
Status: RECRUITING
Conditions: Graft Vs Host Disease|Graft-versus-host-disease
Interventions: DEVICE: CliniMacs®
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of Monolithic Zirconia Crowns
Status: ACTIVE_NOT_RECRUITING
Conditions: Dental Materials
Interventions: PROCEDURE: Monolithic zirconia|PROCEDURE: Metal-ceramic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multi-center Clinical Observation of FCVB in Guangdong Province
Status: UNKNOWN
Conditions: Retina Detachment|Eye Injuries|Eye Atrophy|Silicone Emulsion
Interventions: DEVICE: Foldable Capsular Vitreous Body (FCVB)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: High Confusion: Cannabis & Driving
Status: NOT_YET_RECRUITING
Conditions: Impairment, Cognitive|Impairment of Attention|Impairment, Psychomotor
Interventions: DRUG: Delta-9-THC|DRUG: Delta-8-THC|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluating Cognitive and Functional Impairment in Alzheimer's Dementia With a Ketogenic Diet.
Status: COMPLETED
Conditions: Cognitive Function 1, Social
Interventions: DIETARY_SUPPLEMENT: Bulletproof Brain Octane|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Influenza Challenge Study of VIS410 in Healthy Volunteers
Status: COMPLETED
Conditions: Influenza
Interventions: DRUG: VIS410|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use of ReliZORB for Feeding Intolerance in Critically Ill Patients
Status: WITHDRAWN
Conditions: Multi Organ Failure|Critical Illness
Interventions: DRUG: Relizorb|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Early Versus Late Cholecystectomy After Clearance of Common Bile Duct Stones
Status: COMPLETED
Conditions: Gallbladder and Bile Duct Calculi
Interventions: PROCEDURE: early cholecystectomy|PROCEDURE: late cholecystectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Diagnosis of Cardiac Amyloidosis With 99mTc-PYP; Comparison Between Planar Imaging, SPECT/CT and Cardiac-dedicated CZT Camera
Status: UNKNOWN
Conditions: Cardiac Amyloidosis
Interventions: DIAGNOSTIC_TEST: Spect scan with mTc99-PYP
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effect of Magnesium Therapy to Prevent Post-operative Atrial Fibrillation After Cardiac Surgery in Adults
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DRUG: Magnesium Sulfate|OTHER: control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of Allogenic Stem Cell Product(CARTISTEM®) for Osteochondral Lesion of Talus
Status: COMPLETED
Conditions: Chondral or Osteochondral Lesion of Talus
Interventions: BIOLOGICAL: CARTISTEM®|PROCEDURE: Microfracture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Placebo-controlled Trial of Chronic Total Occlusion Percutaneous Coronary Intervention for the Relief of Stable Angina
Status: RECRUITING
Conditions: Stable Angina|Chronic Total Occlusion of Coronary Artery
Interventions: PROCEDURE: Percutaneous coronary intervention|PROCEDURE: Placebo percutaneous coronary intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Single Dose Study Of PF-05161704 In Healthy Volunteers
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: PF-05161704 or placebo|DRUG: PF-05161704 or placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of Pemetrexed Plus Cisplatin in Advanced Gastric Cancer
Status: COMPLETED
Conditions: Neoplasm, Gastric
Interventions: DRUG: pemetrexed|DRUG: cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasound- Guided Retro Superior Costotransverse Ligament (SCTL) Compartment Block
Status: COMPLETED
Conditions: Thoracic Surgery, Video-Assisted
Interventions: PROCEDURE: Retro SCTL compartment block
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Migraine Treatment With Nerivio Migra Neurostimulation Device
Status: TERMINATED
Conditions: Acute Migraine
Interventions: DEVICE: Nerivio Migra neurostimulation|DEVICE: Sham Nerivio Migra
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Implementation of CRP Point of Care Testing in Primary Care to Improve Antibiotic Targeting in Respiratory Illness (ICAT)
Status: COMPLETED
Conditions: Acute Respiratory Infection
Interventions: DIAGNOSTIC_TEST: ACTIM CRP Rapid Test (Medix, Biochemica)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Donor Peripheral Stem Cell Transplant in Treating Patients With Advanced Hematologic Cancer or Other Disorders
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Myeloproliferative Disorders|Graft Versus Host Disease|Leukemia|Lymphoma|Multiple Myeloma and Plasma Cell Neoplasm|Myelodysplastic Syndromes|Myelodysplastic/Myeloproliferative Diseases|Precancerous/Nonmalignant Condition
Interventions: DRUG: busulfan|DRUG: cyclophosphamide|DRUG: cyclosporine|DRUG: etoposide|DRUG: fludarabine phosphate|DRUG: melphalan|DRUG: methotrexate|DRUG: mycophenolate mofetil|DRUG: sirolimus|DRUG: tacrolimus|PROCEDURE: allogeneic hematopoietic stem cell transplantation|PROCEDURE: peripheral blood stem cell transplantation|RADIATION: total-body irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BXCL501 for Agitation in Schizophrenia
Status: RECRUITING
Conditions: Schizophrenia|Schizoaffective Disorder
Interventions: DRUG: Dexmedetomidine Hydrochloride|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bovine Lactoferrin Versus Ferrous Sulphate In The Treatment Of Iron Deficiency Anemia During Pregnancy
Status: UNKNOWN
Conditions: Anemia During Pregnancy
Interventions: DIETARY_SUPPLEMENT: L (lactoferrin)|DRUG: F (ferrous sulphate)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Herbal Medication (Gongjin-dan) for Chronic Dizziness
Status: UNKNOWN
Conditions: Dizziness Chronic
Interventions: DRUG: Gongjin-Dan|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Non-invasive MRI Subclassification of Heptocellular Carcinoma - HepCaSt-Study
Status: UNKNOWN
Conditions: HCC|Hepatocellular Carcinoma|MRI
Interventions: DRUG: MRI using a hepatobiliary phase contrast agent (Gd-EOB-DPTA)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of Dronabinol For Acute Pain Following Traumatic Injury
Status: WITHDRAWN
Conditions: Traumatic Injury|Pain, Acute
Interventions: DRUG: Adjunctive dronabinol|DRUG: Systemic analgesics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Clinical Efficacy and Safety of Intratumoral Injection of Chemotherapy for Advanced Solid Tumors
Status: RECRUITING
Conditions: Intratumoral Injection|Cancer
Interventions: PROCEDURE: Intratumoral Injection of Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Erector Spinae Plane Block for Paediatric Upper Abdominal Surgery
Status: COMPLETED
Conditions: Paediatric|Surgery|Analgesia|Anesthesia
Interventions: PROCEDURE: Erector Spinae Plain Block|PROCEDURE: Intra-Venous Analgesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of the Safety and Tolerability of V419 in Healthy Infants at 2,4, 6 and 12 to 14 Months of Age (V419-003)
Status: COMPLETED
Conditions: Bacterial Infections; Virus Diseases
Interventions: BIOLOGICAL: AR51 (12, 10)|BIOLOGICAL: PR51 (3, 10)|BIOLOGICAL: PR51 (6, 10)|BIOLOGICAL: PENTACEL™|BIOLOGICAL: RECOMBIVAX HB™
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Effects of Different Types of Non-ventilated Lung Management on DO2 During OLV in the Supine Position
Status: UNKNOWN
Conditions: One-Lung Ventilation|Thoracic Surgery Video Assisted|Supine Position
Interventions: PROCEDURE: Capnothorax|PROCEDURE: Capnothorax and CPAP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT