pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Assesment of the Effectiveness of High Frequency Oral Oscillation and Mask of PEP in Children With Pneumonia
Status: UNKNOWN
Conditions: Pneumonia
Interventions: OTHER: PEP|OTHER: HFOO|OTHER: Assisted Coughing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sodium-Glucose Cotransporter-2 Inhibitor for Acute Cardiorenal Syndrome: A Feasibility Study
Status: RECRUITING
Conditions: Cardiorenal Syndrome
Interventions: DRUG: Dapagliflozin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hybrid Rehabilitation Approach Through Group Exercise and Telerehabilitation in Patients With Multiple Sclerosis
Status: RECRUITING
Conditions: Multiple Sclerosis
Interventions: OTHER: Circuit training followed by telerehabilitation|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Preliminary Study 2 to Test the Effects of Ambulatory Voice Biofeedback
Status: COMPLETED
Conditions: Vocal Fold Nodules|Muscle Tension Dysphonia
Interventions: BEHAVIORAL: Ambulatory voice biofeedback
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 12-h and 2-h Urokinase Regimes of Pulmonary Thromboembolism in China
Status: COMPLETED
Conditions: Pulmonary Embolism|Thromboembolism
Interventions: DRUG: Urokinase|DRUG: Urokinase
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: APC-111 Once a Day (QD) for 7 Days vs. Penicillin Taken Four Times a Day (QID) for 10 Days in Patients With Strep Throat
Status: COMPLETED
Conditions: Pharyngitis|Tonsillitis
Interventions: DRUG: Amoxicillin Pulsatile Release Multiparticulate Tablet (drug)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Colloids in Pediatric Cardiac Surgery: Comparison Between a Balanced and a Non-balanced Colloid
Status: COMPLETED
Conditions: Cardiac Surgery|Cardiopulmonary Bypass
Interventions: DRUG: Hydroxyethyl starch 130/0.4 in an isotonic electrolyte solution|DRUG: Hydroxyethyl starch 130/0.4 in 0.9% sodium chloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Crystalloid Versus Hydroxyethyl Starch Trials
Status: COMPLETED
Conditions: Intensive Care
Interventions: DRUG: 6% Hydroxy-ethyl starch (130/0.4)|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: COVID-19 Infection and Transmission in Exposed, Confined and Community-based Infants
Status: COMPLETED
Conditions: Coronavirus|Coronavirus Infection|Covid19|Sars-CoV2
Interventions: DIAGNOSTIC_TEST: Rapid detection test|DIAGNOSTIC_TEST: Nasopharyngeal swab|DIAGNOSTIC_TEST: Stool collection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study Comparing the Effect of Amorphous Calcium Carbonate (ACC) on Healing Time of Distal Radius Fractures
Status: TERMINATED
Conditions: Distal Radius Fractures
Interventions: DIETARY_SUPPLEMENT: Amorphous calcium carbonate|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of Surface Antigen, Inactivated, Influenza Vaccine Using the Strain Composition 2009/2010 Recommended in Northern Hemisphere in Non-elderly Adult and in Elderly Subjects
Status: COMPLETED
Conditions: Influenza Disease
Interventions: BIOLOGICAL: Influenza vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Human Soil Transmitted Helminths (STH) Resistance to Benzimidazole in School Aged Children Living in Gabon
Status: COMPLETED
Conditions: Helminths Infection|Drug Resistance
Interventions: DRUG: Benzimidazole Anthelmintic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Long-Term Safety and Efficacy of Upadacitinib (ABT-494) in Participants With Ulcerative Colitis (UC)
Status: ACTIVE_NOT_RECRUITING
Conditions: Ulcerative Colitis (UC)
Interventions: DRUG: Upadacitinib (ABT-494)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: COMbination of Clopidogrel and Aspirin for Prevention of Early REcurrence in Acute Atherothrombotic Stroke
Status: COMPLETED
Conditions: Stroke
Interventions: DRUG: Clopidogrel|DRUG: Clopidogrel placebo|DRUG: Aspirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Efalizumab Compared With Cyclosporine As an Immunosuppressant Regimen in De Novo Renal Transplantation
Status: WITHDRAWN
Conditions: Kidney Transplantation
Interventions: DRUG: basiliximab|DRUG: efalizumab|DRUG: mycophenolate mofetil|DRUG: corticosteroids|DRUG: cyclosporine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare the Safety, Pharmacokinetics and Pharmacodynamics of YPI 011 to Rabeprazole in Healthy Adult Subjects
Status: COMPLETED
Conditions: Gastroesophageal Reflux Disease
Interventions: DRUG: Rabeprazole Sodium 10mg|DRUG: Rabeprazole Sodium 20mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: XAD - Xelox (Capecitabine + Oxaliplatin) + Bevacizumab + Dasatinib
Status: COMPLETED
Conditions: Solid Tumor|Metastatic Colorectal Cancer
Interventions: DRUG: dasatinib|DRUG: bevacizumab|DRUG: Oxaliplatin|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Long-term Administration Study of OPC-41061 in Patients With Autosomal Dominant Polycystic Kidney Disease (ADPKD) [Extension of Study 156-04-001]
Status: COMPLETED
Conditions: Autosomal Dominant Polycystic Kidney Disease
Interventions: DRUG: OPC-41061
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Decrease in Circulating Tumour Cell Count Reflects the Effectiveness of Postoperative Adjuvant Transarterial Chemoembolization (TACE) in Preventing Hepatocellular Carcinoma Recurrence
Status: COMPLETED
Conditions: Circulating Tumor Cell;|Hepatocellular Carcinoma
Interventions: PROCEDURE: transarterial chemoembolization (TACE)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SCREENING
Clinical trial: Talazoparib Maintenance Therapy in Triple-negative Breast Cancer
Status: UNKNOWN
Conditions: TNBC - Triple-Negative Breast Cancer
Interventions: DRUG: Talazoparib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Intradermal Trivalent Influenza Vaccination in Institutionalized Older Adults
Status: UNKNOWN
Conditions: Influenza, Human
Interventions: DRUG: Intanza|DRUG: Vaxigrip
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effectiveness of Therapeutic Exercise App Adding a Face-to-face Physical Therapist in Low Back Pain
Status: COMPLETED
Conditions: Low Back Pain
Interventions: OTHER: App and face-to-face physical therapy|OTHER: App physical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Multi-center, Randomized, Double-blind Phase III Clinical Trial to Assess and Compare to the Efficacy and Safety of Lafutidine, Famotidine and Omeprazole-referenced in Korean Erosive Esophagitis Patients
Status: COMPLETED
Conditions: Erosive Esophagitis
Interventions: DRUG: Lafutidine|DRUG: Famotidine|DRUG: Omeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Accuracy Study of Robot-assisted Screw Insertion in Spinal Surgery
Status: UNKNOWN
Conditions: the Robot-assisted Technique
Interventions: DEVICE: the TiRobot system|DEVICE: Freehand
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: External DCR Versus Canalicular SI With MMC in NLDO
Status: COMPLETED
Conditions: Primary Acquired Nasolacrimal Duct Obstruction
Interventions: PROCEDURE: external dacryocystorhinostomy|PROCEDURE: canalicular silicone intubation with MMC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy Testing of VeCollal Products
Status: COMPLETED
Conditions: Skin Condition
Interventions: DIETARY_SUPPLEMENT: Placebo sachet|DIETARY_SUPPLEMENT: VeCollal sachet|DIETARY_SUPPLEMENT: Collagen sachet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: A Study to Evaluate the Product Feasibility of Two New Silicone Hydrogel Contact Lenses
Status: COMPLETED
Conditions: Myopia
Interventions: DEVICE: B&L RD2135-01 lens C|DEVICE: B&L RD2135-01 lens D|DEVICE: PureVision2|DEVICE: Air Optix Aqua
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Adaptive COVID-19 Treatment Trial 4 (ACTT-4)
Status: COMPLETED
Conditions: COVID-19
Interventions: DRUG: Baricitinib|DRUG: Dexamethasone|OTHER: Placebo|DRUG: Remdesivir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I/II Study With Oral Panobinostat Maintenance Therapy Following Allogeneic Stem Cell Transplantation in Patients With High Risk Myelodysplastic Syndrome (MDS) or Acute Myeloid Leukemia (AML)
Status: UNKNOWN
Conditions: Myelodysplastic Syndrome|Acute Myeloid Leukemia
Interventions: DRUG: Panobinostat|DRUG: Panobinostat
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Shortened Antibiotic Treatment of 5 Days in Gram-negative Bacteremia
Status: RECRUITING
Conditions: Gram-negative Bacteremia|Urinary Tract Infection Bacterial
Interventions: OTHER: Shortened antibiotic treatment|OTHER: Standard antibiotic treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I Multicenter Clinical Trial to Evaluate the Safety and Immunogenicity of Vaccinia-Derived HIV-1 Recombinant Envelope Glycoprotein (gp160)
Status: COMPLETED
Conditions: HIV Infections
Interventions: BIOLOGICAL: gp160 Vaccine (Immuno-AG)
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: BRE-04: Window of Opportunity Trial of Preoperative Low Dose Azacitidine in High-Risk Early Stage Breast Cancer
Status: RECRUITING
Conditions: Breast Cancer Female|Breast Cancer Invasive
Interventions: DRUG: Azacitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Finding an Effective Dose of GM1 to Reduce or Prevent Neuropathy (Numbness or Weakness) Due to Treatment With Paclitaxel (Phase II)
Status: RECRUITING
Conditions: Anatomic Stage IV Breast Cancer AJCC v8|Chemotherapy-Induced Peripheral Neuropathy|Metastatic Breast Carcinoma
Interventions: DRUG: Paclitaxel|DRUG: Monosialotetrahexosylganglioside|OTHER: Questionnaire Administration|OTHER: Quality-of-life assessment|DRUG: Placebo Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Group Education to Improve the Iodine Nutrition in Pregnancy: Cluster Randomized Trial
Status: WITHDRAWN
Conditions: Dietary Intervention|Pregnancy Jail|Iodine Deficiency
Interventions: OTHER: Group Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Duration of Peripheral Nerve Blocks in Opioid Tolerant Individuals - A Volunteer Blinded Matched Case-control Study
Status: RECRUITING
Conditions: Nerve Block|Opioid Tolerance
Interventions: OTHER: Radial nerve block
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Two Recall Intervals on Dental Caries Incidence, Anxiety and Quality of Life of Preschool Children
Status: COMPLETED
Conditions: Dental Caries|Quality of Life|Anxiety
Interventions: PROCEDURE: Oral clinical conditions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Bioequivalence Study of Baricitinib From Barcimiant 4 mg Film Coated Tablets (Horus Pharma, Egypt) and Olumiant 4 mg Film Coated Tablets (Eli Lilly Nederland B.V., The Netherlands)
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Barcimiant|DRUG: Olumiant (first dose)|DRUG: Olumiant (second dose)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Safety and Efficacy of the GTS400 Stent in Conjunction With Cataract
Status: COMPLETED
Conditions: Open-angle Glaucoma
Interventions: DEVICE: Glaucoma Stent Surgery (GTS400 Stent)|PROCEDURE: cataract surgery alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: AURAIA Study : Impact Evaluation at 3 Months Follow-up of a Brief Motivational Intervention in Reducing Alcohol Consumption Among Adolescents Aged 16-24 in Pontchaillou Hospital Emergency Department in Rennes, France
Status: COMPLETED
Conditions: Alcohol Abuse, Episodic Drinking Behavior
Interventions: BEHAVIORAL: Brief Motivational Intervention (BMI)|BEHAVIORAL: Simple written advice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Imatinib Mesylate or Observation Only in Treating Patients Who Have Undergone Surgery for Localized Gastrointestinal Stromal Tumor
Status: COMPLETED
Conditions: Gastrointestinal Stromal Tumor
Interventions: DRUG: imatinib mesylate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Exogenous Glucagon-like Peptide 2 on Cholecystokinin-induced Gallbladder Emptying
Status: ACTIVE_NOT_RECRUITING
Conditions: Gallbladder
Interventions: OTHER: GLP-2|OTHER: Placebo|OTHER: CCK|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Solarplast (R) Supplementation Effects Following High-intensity Resistance Exercise
Status: RECRUITING
Conditions: Muscle Damage
Interventions: DIETARY_SUPPLEMENT: Solarplast (R)|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Well-being Interventions on Affect, Attention, Sleep, Social Stress and Pain Regulation
Status: COMPLETED
Conditions: Health|Mental Health
Interventions: BEHAVIORAL: Day of intensive meditation practice|BEHAVIORAL: Mindfulness Based Stress Reduction (MBSR)|BEHAVIORAL: Health Enhancement Program (HEP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Safety of AEYE-DS Software Device for Automated Detection of Diabetic Retinopathy From Digital Fundus Images
Status: COMPLETED
Conditions: Diabetes Mellitus|Diabetic Retinopathy
Interventions: DEVICE: AEYE Software Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of Lademirsen (SAR339375) in Patients With Alport Syndrome
Status: TERMINATED
Conditions: Alport Syndrome
Interventions: DRUG: lademirsen (SAR339375)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Contrasting Group Therapy Methods for Psychosis
Status: TERMINATED
Conditions: Psychosis|Schizophrenia|Schizoaffective Disorder|Schizophreniform Disorder
Interventions: BEHAVIORAL: Metacognitive Training (MCT)|BEHAVIORAL: Cognitive Remediation (CR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cenobamate Open-Label Extension Study for YKP3089C025
Status: ENROLLING_BY_INVITATION
Conditions: Primary Generalized Tonic Clonic Seizures in the Setting of Idiopathic Generalized Epilepsy
Interventions: DRUG: Cenobamate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Comparative Pharmacokinetics of Nicotine After Administration Via JUUL or Tobacco Cigarettes
Status: COMPLETED
Conditions: Nicotine Administration & Dosage|E-cigarettes|Vaping|E-Liquid|Tobacco Smoking
Interventions: OTHER: JUUL|OTHER: Tobacco
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: End-stage Renal Disease (ESRD) Pilot Study
Status: COMPLETED
Conditions: Renal Dialysis
Interventions: DRUG: BAY1213790|DRUG: 0.9% sodium chloride solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Antidepressants and Bone Mineral Density
Status: COMPLETED
Conditions: Bone Mineral Density Quantitative Trait Locus 7
Interventions: DRUG: sertraline|DRUG: citalopram|DRUG: venlafaxine|DRUG: reboxetine|BEHAVIORAL: control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Safety, Tolerability and Efficacy of DFV890 in Participants With Familial Cold Auto-inflammatory Syndrome (FCAS)
Status: COMPLETED
Conditions: Familial Cold Autoinflammatory Syndrome
Interventions: DRUG: DFV890
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Hormonal Contraception on HIV Acquisition and Transmission Risk
Status: COMPLETED
Conditions: HIV|Contraception
Interventions: DRUG: Depot medroxyprogesterone acetate (DMPA)|DEVICE: Etonogestrel implant (Eng-Implant)|DEVICE: Levonorgestrel intrauterine device (Lng-IUD)|DEVICE: ParaGard® T 380A Intrauterine Copper Contraceptive
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Assessing the Value of Avocados on Glycemic Control in Type 2 Diabetes
Status: RECRUITING
Conditions: Diabetes Mellitus, Type 2|Insulin|Fructosamine|C-Reactive Protein|Glucose|Overweight and Obesity
Interventions: OTHER: Avocado|OTHER: Other Fruit(s)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I, Dosage-finding and PK Study of IV Topotecan and Erlotinib With Refractory Solid Tumors
Status: COMPLETED
Conditions: Metastatic Solid Tumor
Interventions: DRUG: Topotecan|DRUG: Erlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Exercise Training on Exercise Capacity and Sleep Quality in Patients With Obesity Hypoventilation Syndrome
Status: RECRUITING
Conditions: Obesity Hypoventilation Syndrome (OHS)|Hypoventilation|Obesity|Respiration Disorders|Sleep Disorder
Interventions: OTHER: Exercises and Diet|OTHER: Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ultrasound-guided Treatment in Acute Heart Failure
Status: WITHDRAWN
Conditions: Acute Heart Failure|Congestion
Interventions: DIAGNOSTIC_TEST: Cardiothoracic ultrasound protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety, Effectiveness, and Impact on Quality of Life on Long-Term Administration of OROS Hydromorphone Slow-Release in Patients With Chronic Low Back Pain
Status: COMPLETED
Conditions: Low Back Pain
Interventions: DRUG: OROS hydromorphone HCI SR (slow release)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics Study of JNJ-28431754 in Patients With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: JNJ 28431754|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Wheelchair Handrail Compensator and Rehabilitation Training for Patients With Hemiplegic Shoulder Pain
Status: COMPLETED
Conditions: Shoulder Pain
Interventions: DEVICE: Wheelchair handrail compensator|DEVICE: Ordinary wheelchair
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: JY231(JY231) Injection for the Treatment of B-cell Acute Lymphoblastic Leukemia(B-ALL)
Status: RECRUITING
Conditions: B-cell Acute Lymphoblastic Leukemia( B-ALL )
Interventions: BIOLOGICAL: JY231
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 1A Study of the Safety of KSP/QRH Dimer
Status: COMPLETED
Conditions: Healthy Adults
Interventions: DRUG: KSP-QRH-E3-IRDye800 (Peptide 919288G), 0.6 mg|DRUG: KSP-QRH-E3-IRDye800 (Peptide 919288G), 1.8 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Safety and Efficacy of Next Generation Ophthalmic Irrigating Solution Compared to BSS Plus
Status: COMPLETED
Conditions: Cataract
Interventions: DRUG: Next Generation Ophthalmic Irrigating Solution (NGOIS)|DRUG: BSS Plus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Exercise Among Turtle Neck Syndrome in Pakistani Patients
Status: COMPLETED
Conditions: Neck Pain
Interventions: PROCEDURE: myofascial release|PROCEDURE: muscle energy technique|PROCEDURE: MFR & MET|PROCEDURE: conventional therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Enhanced E-cigarette Coaching Intervention for Dual Users of Cigarettes and E-cigarettes
Status: COMPLETED
Conditions: Smoking Cessation
Interventions: BEHAVIORAL: Enhanced E-cigarette Coaching|BEHAVIORAL: Quitline treatment as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Molidustat for Treatment of Renal Anemia in Peritoneal Dialysis Subjects
Status: COMPLETED
Conditions: Anemia|Renal Insufficiency, Chronic
Interventions: DRUG: Molidustat (BAY85-3934)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Naltrexone for Medication Compliance Among HIV-infected Men With Alcohol Use Disorder
Status: COMPLETED
Conditions: HIV|Alcohol Use Disorder
Interventions: DRUG: oral naltrexone|DRUG: Placebo pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Resveratrol and Vascular Function in CKD
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Kidney Diseases|Endothelial Dysfunction
Interventions: DIETARY_SUPPLEMENT: Resveratrol|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of TAS1440 With ATRA in Subjects With r/r AML
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: TAS1440|DRUG: TAS1440 + ATRA
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of AC Followed by a Combination of Paclitaxel Plus Trastuzumab or Lapatinib or Both Given Before Surgery to Patients With Operable HER2 Positive Invasive Breast Cancer
Status: UNKNOWN
Conditions: Invasive Breast Cancer
Interventions: DRUG: doxorubicin|DRUG: cyclophosphamide|DRUG: paclitaxel|DRUG: trastuzumab|DRUG: lapatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Affixing Polypropylene Mesh Using Barbed Suture (Quill™ SRS) During Robotic Assisted Laparoscopic Sacrocolpopexy
Status: UNKNOWN
Conditions: Prolapse
Interventions: DEVICE: Device is the type of suture used: Quill suture vs. Interrupted suture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Effect of Renal Impairment on the Activity of GK Activator (2) in Patients With Type 2 Diabetes.
Status: COMPLETED
Conditions: Diabetes Mellitus Type 2
Interventions: DRUG: GK Activator (2)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of 18F-AlF-NOTA-octreotide PET/CT for Imaging Neuroendocrine Neoplasms
Status: UNKNOWN
Conditions: Neuroendocrine Neoplasm
Interventions: DRUG: 18F-AlF-NOTA-octreotide|DEVICE: PET/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Birinapant for Advanced Ovarian, Fallopian Tube, and Peritoneal Cancer
Status: TERMINATED
Conditions: Epithelial Ovarian Cancer|Peritoneal Neoplasms|Fallopian Tube Neoplasms
Interventions: DRUG: Birinapant (TL32711)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Music Therapy and Digital Music Rehabilitation in Dementia
Status: NOT_YET_RECRUITING
Conditions: Dementia
Interventions: BEHAVIORAL: Conventional music therapy (CMT)|BEHAVIORAL: Digital music rehabilitation (DMR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Epidemiology of Papillomavirus Infection (HPV) on Infected Women by Human Immunodeficience Virus (HIV) in West Indies and French Guiana.
Status: COMPLETED
Conditions: 1- Women|2- HIV Infection|3- Followed in West Indies and French Guiana for His Infection|4- Acceptance of the Use of Nadis® Medical Files
Interventions: OTHER: Biological Sample collection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Long-term Safety Study With Tapentadol ER and Oxycodone CR in Patients With Moderate to Severe Pain Due to Chronic, Painful Diabetic Peripheral Neuropathy (DPN)
Status: TERMINATED
Conditions: Diabetic Neuropathy, Painful|Diabetic Polyneuropathy
Interventions: DRUG: Tapentadol extended release (ER)|DRUG: Oxycodone controlled release (CR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A 6-month Study to Evaluate Sulforaphane Effects in Schizophrenia Patients
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Sulforaphane|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cinacalcet Versus Parathyroidectomy in Peritoneal Dialysis Patients
Status: COMPLETED
Conditions: Kidney Failure|Secondary Hyperparathyroidism|Vascular Diseases
Interventions: DRUG: Cinacalcet|PROCEDURE: Surgical total parathyroidectomy with forearm autografting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pulpotomy Technique Preserving Vitality of Traumatized Anterior Permanent Immature Teeth
Status: COMPLETED
Conditions: Pulp Exposure, Dental
Interventions: BIOLOGICAL: Biodentine|BIOLOGICAL: mineral trioxide aggregate|PROCEDURE: cervical pulpotomy|DRUG: Local Anesthetics Procaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Providing Tools for Effective Care and Treatment of Anxiety Disorders
Status: COMPLETED
Conditions: Panic Disorder|Agoraphobia|Specific Phobias|Social Anxiety Disorder
Interventions: BEHAVIORAL: Intensified psychological intervention|BEHAVIORAL: Standard intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Dosing and Timing Study to Optimize Imaging When Utilizing Endoscopic Fluorescence Imaging System During Laparoscopic Biliary and Hepatic Operations
Status: COMPLETED
Conditions: Biliary Anatomy
Interventions: DEVICE: PINPOINT System
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Atenolol Versus Ivabradine on HRV in TRS Patients on Clozapine With Tachycardia: A Randomised Control Trial.
Status: RECRUITING
Conditions: Treatment Resistant Schizophrenia|Clozapine Adverse Reaction|Heart Rate Variability|Tachycardia
Interventions: DRUG: Atenolol 25 mg|DRUG: Ivabradine 10mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study of Monthly Subcutaneous Continuous Erythropoietin Receptor Activator (CERA) in Predialysis Participants With Chronic Renal Anemia
Status: COMPLETED
Conditions: Anemia
Interventions: DRUG: Methoxy Polyethylene Glycol-Epoetin Beta
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bortezomib in Treating Patients With Advanced Non-small Cell Lung Cancer
Status: TERMINATED
Conditions: Recurrent Non-small Cell Lung Cancer|Stage IIIB Non-small Cell Lung Cancer|Stage IV Non-small Cell Lung Cancer
Interventions: DRUG: bortezomib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Neurodynamic Mobilization Techniques in Patients With Diabetic Neuropathy
Status: COMPLETED
Conditions: Diabetic Neuropathies
Interventions: OTHER: Neurodynamic Mobilization Techniques|OTHER: Selected Physical Therapy Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Implantation of Olfactory Ensheathing Cells (OECs)
Status: UNKNOWN
Conditions: Infarction, Middle Cerebral Artery|Ischemic Stroke,|Stroke With Hemiparesis,|Thromboembolic Stroke.
Interventions: PROCEDURE: Olfactory ensheathing cells
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Combination of Iguratimod and Danazol as the Treatment of Steroid-resistant/Relapse Immune Thrombocytopenia
Status: UNKNOWN
Conditions: ITP|Immune Thrombocytopenia
Interventions: DRUG: Iguratimod|DRUG: Danazol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Airway Effects of Tiotropium in Patients With COPD
Status: COMPLETED
Conditions: COPD|LUNG DISEASES, OBSTRUCTIVE
Interventions: COMBINATION_PRODUCT: Handihaler-Tiotropium 18 mcg untrained|COMBINATION_PRODUCT: Handihaler-Tiotropium 18 mcg trained|COMBINATION_PRODUCT: Respimat-Tiotropium 5 mcg trained
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hand-Arm Bimanual Intensive Therapy in Virtual Reality Versus Standard Hand-Arm Bimanual Intensive Therapy
Status: RECRUITING
Conditions: Hemiplegic Cerebral Palsy
Interventions: BEHAVIORAL: HABIT-VR|BEHAVIORAL: Standard HABIT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose Escalation for SBRT of Recurrent VT Ventricular Tachyarrhythmia - a Single Center, Phase II Clinical Trial
Status: RECRUITING
Conditions: Ventricular Tachycardia
Interventions: DEVICE: Dose escalating stereotactic arrhythmia radioablation to treat ventricular tachycardia (VT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lepticore in Metabolic Syndrome and Weight Loss
Status: COMPLETED
Conditions: Obesity|Hyperlipidemia|Hyperglycemia
Interventions: DIETARY_SUPPLEMENT: Lepticore
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Implications of Appropriate Use of Inhalers in Chronic Obstructive Pulmonary Disease (COPD)
Status: WITHDRAWN
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DIAGNOSTIC_TEST: In Check Dial test
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Diacerein 50 mg Capsule in Healthy Thai Volunteers
Status: NOT_YET_RECRUITING
Conditions: Healthy Volunteer
Interventions: DRUG: Diacerein 50 mg Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Clinical Study of Post-operative Proton Radiotherapy for Thymus Tumor
Status: RECRUITING
Conditions: Thymus Epithelial Tumor|Proton Radiotherapy|Radiation Toxicity
Interventions: RADIATION: Proton radiotherapy|OTHER: combined platinum based chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Noninvasive Continuous Cardiac Output by the Clearsight With Invasive Monitoring by Pulsioflex in Abdominal Surgery
Status: COMPLETED
Conditions: Cardiac Output Measurement
Interventions: DEVICE: Cardiac output and stroke ejection volume monitoring with arterial waveform analysis in the digital artery (ClearSight®)|DEVICE: Cardiac output and stroke ejection volume monitoring with arterial waveform analysis in the radial artery (Pulsioflex®).
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Study With Oral Ferric Maltol for the Treatment of Iron Deficiency Anemia in Subjects With Chronic Kidney Disease
Status: COMPLETED
Conditions: Renal Insufficiency, Chronic|Iron-Deficiency Anemia
Interventions: DRUG: Ferric maltol|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Interest of Wicking for Ossicular Surgery and Myringoplasty
Status: RECRUITING
Conditions: Post-Op Complication|Otologic Disease
Interventions: PROCEDURE: Wicking|PROCEDURE: No wicking
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: QuitFast: Evaluating Transcranial Magnetic Stimulation as a Tool to Reduce Smoking Directly Following a Quit Attempt
Status: TERMINATED
Conditions: Smoking, Cigarette|Craving|Addiction|Nicotine
Interventions: DEVICE: Real cTBS|DEVICE: Sham cTBS|DEVICE: Real iTBS|DEVICE: Sham iTBS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cadonilimab Plus mFOLFIRINOX as Conversion Therapy in LAPC
Status: NOT_YET_RECRUITING
Conditions: Pancreatic Cancer
Interventions: DRUG: Cadonilimab+mFOLFIRINOX
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nicotine Treatment of Mild Cognitive Impairment (MCI)
Status: UNKNOWN
Conditions: Age-Related Memory Disorders
Interventions: DRUG: Transdermal nicotine patch|DRUG: Placebo transdermal patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Efficacy and Safety Study of Infliximab in Participants With Rheumatoid Arthritis
Status: COMPLETED
Conditions: Arthritis, Rheumatoid
Interventions: DRUG: Infliximab|DRUG: Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Specific Balance Training Prior TKR Surgery in the Early Postoperative Outcomes
Status: COMPLETED
Conditions: Knee Osteoarthritis|Aging
Interventions: OTHER: Strength-Function|OTHER: Balance-Proprioception
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparison Between Conventional Throat Packs and Pharyngeal Placement of Tampons in Rhinology Surgeries
Status: COMPLETED
Conditions: Pain|Postoperative Pain|Bleeding|Nose Bleed
Interventions: OTHER: Throat Pack|OTHER: Pharyngeal Tampons
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Singing-based Music Therapy Program on the Level of Psychoemotional Benefits in Caregivers of ICU Patients
Status: COMPLETED
Conditions: Primary Family Caregivers of ICU Patients
Interventions: BEHAVIORAL: singing-based music therapy program
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nisin in Oral Cavity Squamous Cell Carcinoma (OCSCC)
Status: RECRUITING
Conditions: Oral Cavity Squamous Cell Carcinoma
Interventions: DRUG: NisinZ® P|PROCEDURE: Surgery (non-interventional, standard of care)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Follow-up of Abnormal and Inadequate Smear-test Results
Status: UNKNOWN
Conditions: Carcinoma in Situ of Uterine Cervix
Interventions: OTHER: Test result sent by letter|OTHER: Test result conveyed by general practitioners
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Toripalimab Plus Lenvatinib as Second-line Treatment in Advanced Biliary Tract Cancers
Status: RECRUITING
Conditions: Advanced Biliary Tract Cancer
Interventions: DRUG: Toripalimab plus Lenvatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Closure of Skin in ChorioAmnionitis Research Pilot Study
Status: UNKNOWN
Conditions: Chorioamnionitis|Pregnancy Complications, Infectious|Complications; Cesarean Section|Postoperative Complications
Interventions: PROCEDURE: Suture closure|PROCEDURE: Staples closure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Capecitabine/Tesetaxel Versus Capecitabine/Placebo as Second-line Therapy for Gastric Cancer
Status: UNKNOWN
Conditions: Gastric Carcinoma
Interventions: DRUG: Tesetaxel|DRUG: Placebo|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Combined Effects of Sequential Variety and Portion Size on Meal Intake of Women
Status: COMPLETED
Conditions: Eating Behavior
Interventions: OTHER: Sequential Variety|OTHER: Single-Food|OTHER: Small Portion|OTHER: Large Portion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect Of Vıdeo-Based Fıstula Care Educatıon On Hemodıalysıs
Status: COMPLETED
Conditions: Hemolysis
Interventions: OTHER: Video based education|OTHER: Face to face education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of HRO761 Alone or in Combination in Cancer Patients With Specific DNA Alterations Called Microsatellite Instability or Mismatch Repair Deficiency.
Status: RECRUITING
Conditions: MSIhi or dMMR Advanced Unresectable or Metastatic Solid Tumors, Including Colorectal Cancers
Interventions: DRUG: HRO761|BIOLOGICAL: tislelizumab|DRUG: irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antioxidant Effect of Aged Garlic Extract
Status: COMPLETED
Conditions: Heavy Smoker or Non-smoker
Interventions: DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: Aged garlic extract
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Esomeprazole Treatment Co-diagnosed Non Erosive Reflux Disease (NERD) and Chronic Gastritis Patients
Status: COMPLETED
Conditions: Non Erosive Reflux Disease|Chronic Gastritis
Interventions: DRUG: Esomeprazole|DRUG: Esomeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of ASP4901 in Patients With Benign Prostate Hyperplasia
Status: COMPLETED
Conditions: Benign Prostate Hyperplasia
Interventions: DRUG: ASP4901|DRUG: Tamsulosin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Preference for Clarinex Tablets vs Allegra Tablets in Patients With Seasonal Allergies (P03178)
Status: COMPLETED
Conditions: Seasonal Allergic Rhinitis
Interventions: DRUG: desloratadine 5 mg|DRUG: fexofenadine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Effectiveness of the Screening Inventory of Psychosocial Problems (SIPP) in Cancer Patients
Status: COMPLETED
Conditions: Breast Cancer|Lung Cancer|Prostate Cancer|Bladder Cancer|Cervix Cancer|Cancer of Endometrium|Cancer of Skin|Non-Hodgkin Lymphoma|Colorectal Cancer
Interventions: OTHER: Questionnaire administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Advair HFA in Healthy and HAPE Predisposed Subjects
Status: RECRUITING
Conditions: Altitude Edema
Interventions: DRUG: Advair HFA|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy With or Without Chemoembolization in Treating Patients With Colorectal Cancer Metastatic to the Liver (6655)
Status: TERMINATED
Conditions: Colorectal Cancer|Metastatic Cancer
Interventions: DRUG: FOLFIRI regimen|DRUG: cisplatin|DRUG: doxorubicin hydrochloride|DRUG: fluorouracil|DRUG: irinotecan hydrochloride|DRUG: leucovorin calcium|DRUG: mitomycin C
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT