pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Telehealth for the Self-Management of Dietary Quality of Life in Patients After Stomach Cancer Surgery
Status: ACTIVE_NOT_RECRUITING
Conditions: Gastric Carcinoma|Gastroesophageal Junction Adenocarcinoma
Interventions: OTHER: Best Practice|OTHER: Questionnaire Administration|OTHER: Telemedicine Visit
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Exploratory Evaluation of the Effect of Cholestyramine on Serum Levels of POPs in Obese Female Patients
Status: NOT_YET_RECRUITING
Conditions: Obesity, Abdominal|Diabetes|Bariatric Surgery Candidate
Interventions: DRUG: Cholestyramine Powder
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Bosentan in Progressive Pulmonary Sarcoidosis
Status: TERMINATED
Conditions: Sarcoidosis|Pulmonary Hypertension
Interventions: DRUG: bosentan|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I Oncovir Poly IC:LC and NY-ESO-1/gp100
Status: COMPLETED
Conditions: Melanoma
Interventions: DRUG: CP 870,893|BIOLOGICAL: Peptides|BIOLOGICAL: Oncovir poly IC:LC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Preventive Effect of Chlorhexidine Acetate Gargle for Upper Gastrointestinal Tract Infection After ESD
Status: UNKNOWN
Conditions: Esophageal Cancer|Gastric Cancer
Interventions: DRUG: chlorhexidine acetate gargle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: ORACLE: A Long-term Follow-up Study to Evaluate the Safety of GT005 in Participants With Geographic Atrophy Secondary to Age-related Macular Degeneration Treated in a Gyroscope-sponsored Antecedent Study
Status: ENROLLING_BY_INVITATION
Conditions: Age Related Macular Degeneration (AMD)
Interventions: GENETIC: GT005
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Clinical Applications of Advanced Ophthalmic Imaging
Status: RECRUITING
Conditions: Multiple Sclerosis|Dry Eye Syndromes|Diabetic Retinopathy|Presbyopia|Myopia|Dementia
Interventions: DIETARY_SUPPLEMENT: Ocufolin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect Of Risedronate On Bone Mass In Older Men Receiving Neoadjuvant Therapy For Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: risedronate|DRUG: Placebo risedronate oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: To Compare the Response Rate of Noradrenaline vs. Terlipressin in Hepatorenal Syndrome in Patients With Acute on Chronic Liver Failure
Status: COMPLETED
Conditions: Acute on Chronic Liver Failure
Interventions: DRUG: Nor adrenaline + albumin|DRUG: Terlipressin + albumin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Combination Therapy of TACE and Ablation With Durvalumab in Hepatocellular Carcinoma at Intermediate Stage (TAD)
Status: NOT_YET_RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Durvalumab|PROCEDURE: Transcatheter Hepatic Arterial Chemoembolization (TACE)|PROCEDURE: Ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Oxytocin and Vasopressin Antagonists on Uterine Contractions
Status: COMPLETED
Conditions: In Vitro Fertilisation (IVF) Treatment
Interventions: DRUG: Barusiban|DRUG: Atosiban|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: GSK1325756 Relative Bioavailability Study in Healthy Elderly Subjects
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Danirixin|DRUG: Omeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adding Adjuvant Cisplatin and Gemicitabine Versus Capecitabine in Triple-negative Breast Cancer Patients in Non pCR After Neoadjuvant Standard Chemotherapy
Status: NOT_YET_RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Cisplatin injection and gemcitabine|DRUG: Capecitabine tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Transurethral Bulking Agent Injection Versus Single-Incision Sling for Stress Urinary Incontinence
Status: NOT_YET_RECRUITING
Conditions: Stress Urinary Incontinence|Urinary Incontinence|Mixed Urinary Incontinence
Interventions: DEVICE: Solyx Single-incision Sling|DEVICE: Bulkamid Transurethral Bulking Agent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Impact of Waterpipe Tobacco Flavors on Waterpipe Smoking Intentions, Perceptions, Patterns, and Toxicant Exposure
Status: COMPLETED
Conditions: Smoking, Hookah|Waterpipe Smoking
Interventions: BEHAVIORAL: Flavored-Sweetened Waterpipe Tobacco|BEHAVIORAL: Unflavored-sweetened waterpipe tobacco|BEHAVIORAL: Unflavored-very low sweetened waterpipe tobacco|BEHAVIORAL: Flavored-very low sweetened waterpipe
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Triclosan-antibacterial Sutures Impact on the Incidence of Surgical Site Infection in Laparoscopic Surgeries.
Status: COMPLETED
Conditions: Laparoscopic Surgery|Surgical Wound|Surgical Site Infection
Interventions: DRUG: Coated Vicryl plus|DRUG: Coated vicryl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of the Efficacy and the Cutaneous Acceptability of a Dermocosmetic Product in the Repigmentation of Vitiligo
Status: UNKNOWN
Conditions: Vitiligo
Interventions: OTHER: Lithium liposome|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Docetaxel, Gemcitabine, and Filgrastim (G-CSF) or Pegfilgrastim in Treating Patients With Advanced, Persistent, or Recurrent Uterine Leiomyosarcoma
Status: COMPLETED
Conditions: Sarcoma
Interventions: BIOLOGICAL: filgrastim|BIOLOGICAL: pegfilgrastim|DRUG: docetaxel|DRUG: gemcitabine hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dexmedetomidine to Improve Outcomes of ARDS in Critical Care COVID-19 Patients
Status: UNKNOWN
Conditions: Acute Respiratory Distress Syndrome|Inflammation|Dexmedetomidine|Cytokine Storm|Delirium, Emergence
Interventions: DRUG: Dexmedetomidine Injectable Product
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluate Use of Caudal Nerve Blocks in Adult Penile Prosthesis
Status: COMPLETED
Conditions: Malignant Neoplasms of Male Genital Organs
Interventions: PROCEDURE: Caudal Nerve Block (CNB)|DRUG: Ropivacaine|DRUG: Epinephrine|DRUG: Decadron|DRUG: Clonidine|DRUG: Propofol|BEHAVIORAL: Phone Call
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Near Infrared Fluorescence Cholangiography (NIRF-C) During Cholecystectomy -- Use in Acute Cholecystitis Sub-Study
Status: COMPLETED
Conditions: Acute Cholecystitis|Acute Cholangitis
Interventions: DRUG: Indocyanine Green (ICG)|DEVICE: Near Infrared Fluorescence Cholangiography (NIRF-C)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Treatment of Egyptian Hepatitis C Genotype 4 Infected Children and Adolescents With Combined Ledipasvir/Sofosbuvir
Status: UNKNOWN
Conditions: Hepatitis C Genotype 4
Interventions: DRUG: Combined therapy LDV and SOF
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vitamin E on Staple Line and Anastomoses of Roux-en-Y Gastric Bypass
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: Vitamine E Acetate|DRUG: No application of vitamin E acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of Everolimus and (STZ-5FU) Given One Upfront the Other Upon Progression in Advanced Pancreatic Neuroendocrine Tumor (pNET)
Status: COMPLETED
Conditions: Neuroendocrine Tumors
Interventions: DRUG: Drug: Everolimus|DRUG: STZ-5FU
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Blood Loss Between Surgical Blade and Unipolar Electrocautery in TKA
Status: COMPLETED
Conditions: Blood Loss
Interventions: PROCEDURE: surgical blade|PROCEDURE: electrocautery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Learn How the Study Medicine Danuglipron is Taken Up Into the Blood and If Danuglipron Changes How the Body Processes Other Study Medicines (Atorvastatin and Rosuvastatin) in Healthy Adults Who Are Overweight or Obese
Status: NOT_YET_RECRUITING
Conditions: Obesity
Interventions: DRUG: Danuglipron|DRUG: Atorvastatin|DRUG: Rosuvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Harambee: Integrated Community-based HIV/NCD Care & Microfinance Groups in Kenya
Status: ACTIVE_NOT_RECRUITING
Conditions: HIV/AIDS|Noncommunicable Diseases|Hypertension|Diabetes
Interventions: OTHER: Integrated Community-Based (ICB) Care|OTHER: Microfinance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study to Investigate the Impact of a Multiple Micronutrient (MMN) Beverage Powder on Vaccine Response in School Children
Status: WITHDRAWN
Conditions: Growth and Development
Interventions: DIETARY_SUPPLEMENT: Test Product|DIETARY_SUPPLEMENT: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Role of Nitrogen Oxide (NO) in the Control of Choroidal Blood Flow During a Decrease in Ocular Perfusion Pressure
Status: COMPLETED
Conditions: Physiology, Ocular|Microcirculation|Regional Blood Flow|Autoregulation
Interventions: PROCEDURE: Suction cup application|PROCEDURE: Laser Doppler flowmetry|PROCEDURE: Measurement of intraocular pressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intelligent Moxibustion Robot in the Treatment of Low Back Pain
Status: RECRUITING
Conditions: Moxibustion|Low Back Pain
Interventions: OTHER: Intelligent Moxibustion Robot|OTHER: Artificial moxibustion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testing if BCG (Bacille Calmette-Guérin) Vaccination Can Induce Innate Immune Training in Adult People Above 50 Years of Age in Guinea-Bissau
Status: COMPLETED
Conditions: Innate Immunity|Bacille Calmette-Guérin
Interventions: BIOLOGICAL: Bacille Calmette-Guerin|BIOLOGICAL: BCG solvent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Oxaliplatin Plus Irinotecan in Treating Patients With Metastatic Gastrointestinal Cancer
Status: COMPLETED
Conditions: Anal Cancer|Colorectal Cancer|Esophageal Cancer|Extrahepatic Bile Duct Cancer|Gallbladder Cancer|Gastric Cancer|Gastrointestinal Carcinoid Tumor|Liver Cancer|Pancreatic Cancer|Small Intestine Cancer
Interventions: DRUG: irinotecan hydrochloride|DRUG: oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: A Multi-domain Approach for the Characterization and Early Diagnosis of Neurodevelopmental Disorders
Status: COMPLETED
Conditions: Neurodevelopmental Disorders
Interventions: DIAGNOSTIC_TEST: EEG|DIAGNOSTIC_TEST: DNA samples|DIAGNOSTIC_TEST: clinical data|OTHER: environmental data
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Extension to the Study of Efficacy of CDZ173 in Patients With APDS/PASLI
Status: ACTIVE_NOT_RECRUITING
Conditions: Activated PI3Kdelta Syndrome (APDS); PASLI Disease
Interventions: DRUG: CDZ173
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pancreas-sparing Duodenectomy Versus Pancreatoduodenectomy for Early-stage Periampullary Carcinoma
Status: UNKNOWN
Conditions: Periampullary Carcinoma Nos
Interventions: PROCEDURE: Pancreas-sparing duodenectomy|PROCEDURE: Pancreaticoduodenectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Role of FAM19A4 and Hsa-mir-124 Methylation in Predicting Prognosis of Untreated Cervical Intraepithelial Neoplasia 2 (CIN 2)
Status: UNKNOWN
Conditions: Cervical Intraepithelial Neoplasia Grade 2|DNA Methylation
Interventions: DIAGNOSTIC_TEST: Testing DNA methylation test for predicting prognosis of untreated CIN 2
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Impact of Different Hemostasis Methods on Ovarian Function and Fertility During Laparoscopic Ovarian Cystectomy of Benign Ovarian Cyst
Status: RECRUITING
Conditions: Ovarian Cyst Benign
Interventions: COMBINATION_PRODUCT: the absorbable hemostat and suture|COMBINATION_PRODUCT: electrocoagulation and suture|OTHER: suture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Procedural Pain Management by Multimodal Sedation Analgesia Combining Hypnosis in Children With Congenital Heart Disease
Status: NOT_YET_RECRUITING
Conditions: Procedural Pain|Congenital Heart Disease|Heart Surgery|Hypnosis
Interventions: OTHER: Hypnosis|DRUG: Conventional medications used for sedation-analgesia|DRUG: Medications used in addition to hypnosis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effects of Single Doses of MK-1064 and MK-6096 on Polysomnography (PSG) (MK-1064-003)
Status: COMPLETED
Conditions: Polysomnography
Interventions: DRUG: MK-1064|DRUG: MK-6096|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Subcutaneous Lavage in Cesarean Section
Status: NOT_YET_RECRUITING
Conditions: Surgical Site Infection
Interventions: PROCEDURE: Subcutaneous washing|PROCEDURE: no subcutaneous washing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Cemented and Cementless Fixation of Dual-mobility Hip Prosthesis in Elderly Patients With Osteoarthritis
Status: COMPLETED
Conditions: Osteoarthritis, Hip|Arthropathy of Hip
Interventions: PROCEDURE: cup fixation|DEVICE: Avantage® Cup
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study of RNS60 on Pain and Function After Knee Anterior Cruciate Ligament Surgery
Status: WITHDRAWN
Conditions: Anterior Cruciate Ligament Reconstruction
Interventions: DRUG: RNS60
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of BGB-A445 in Combination With Other Investigational Agents in Participants With Non-Small Cell Lung Cancer
Status: RECRUITING
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: BGB-A445|DRUG: Docetaxel|DRUG: Ramucirumab|DRUG: BGB-15025
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Shoulder Eccentric External Rotator Training for Subacromial Pain Syndrome
Status: COMPLETED
Conditions: Subacromial Impingement Syndrome
Interventions: OTHER: Eccentric Shoulder External Rotator Training|OTHER: General Shoulder exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Evaluation of Aminophylline and Methazolamide
Status: COMPLETED
Conditions: Mountain Sickness
Interventions: DRUG: Aminophylline|DRUG: Methazolamide|DRUG: Aminophylline and Methazolamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Simulation Teaching Method and Vaginal Examination in Midwifery Students
Status: COMPLETED
Conditions: Vaginal Examination
Interventions: BEHAVIORAL: Simulation education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study of CS-1008 in Patients With Advanced Solid Malignancies and Lymphomas (Without Leukemic Component)
Status: COMPLETED
Conditions: Malignancies|Lymphoma
Interventions: DRUG: CS-1008 (humanized anti-DR5 antibody)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: "Palivizumab Therapy for RSV-bronchiolitis"
Status: COMPLETED
Conditions: Respiratory Syncytial Virus-bronchiolitis
Interventions: DRUG: Palivizumab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ventilator Associated Pneumonia in Taper Guard Versus Normal Tube in ICU Patients
Status: UNKNOWN
Conditions: Ventilator Associated Pneumonia
Interventions: DEVICE: Taper Guard Endotracheal Tube|OTHER: Conventional endotracheal tube
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: BD-Covered Stent for Benign Esophageal Strictures: a Safety and Feasibility Study
Status: UNKNOWN
Conditions: Benign Esophageal Stricture
Interventions: DEVICE: BD-Covered esophageal stent
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prophylactic Early PN in HPT/BMT
Status: UNKNOWN
Conditions: Hematologic Neoplasms
Interventions: DIETARY_SUPPLEMENT: Parenteral nutrition.|OTHER: Pragmatic standard care.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of Two Dosing Regimens of GW433908/Ritonavir Versus Lopinavir/Ritonavir for 48 Weeks in HIV Patients Who Have Taken Protease Inhibitors and Experienced Virological Failure
Status: UNKNOWN
Conditions: HIV Infections
Interventions: DRUG: Lopinavir/Ritonavir|DRUG: Ritonavir|DRUG: GW433908
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: BAY79-4980 Compared to rFVIII-FS in Previously Treated Patients With Severe Hemophilia A
Status: TERMINATED
Conditions: Hemophilia A
Interventions: BIOLOGICAL: rFVIII-FS/pegylated liposomes (BAY79-4980)|BIOLOGICAL: rFVIII-FS/WFI (BAY14-2222)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Omnipod® 5 With Libre 2 vs. MDI for Type 1 Diabetes in Children and Adults
Status: ACTIVE_NOT_RECRUITING
Conditions: Diabetes Mellitus, Type 1
Interventions: DEVICE: Omnipod 5 System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High Dose of Dual Therapy Plus Metronidazole for Helicobacter Pylori RescueTreatment
Status: COMPLETED
Conditions: Helicobacter Pylori Infection
Interventions: DRUG: Esomeprazole|DRUG: Amoxicillin|DRUG: Metronidazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prevention of Contrast-Induced Nephropathy
Status: COMPLETED
Conditions: Contrast-induced Nephropathy|Acute Renal Failure|Chronic Renal Failure
Interventions: DRUG: intravenous saline hydration + mannitol + furosemide|DRUG: intravenous saline hydration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Investigate Nicotinic Acid on VEGFR Inhibitor-Associated Hand-Foot Skin Reactions
Status: UNKNOWN
Conditions: Hand-Foot Skin Reaction (HFSR)
Interventions: DRUG: Nicotinic acid +Routine care|DRUG: Routine care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pompage and Photobiomodulation on Pain, Range of Motion, and Quality of Life in Patients With Neck Pain
Status: NOT_YET_RECRUITING
Conditions: Cervicalgia
Interventions: DEVICE: Photobiomodulation (Experimental)|PROCEDURE: Pompage Technique (manual therapy)|DEVICE: Photobiomodulation (Placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bioavailability and Bioequivalence Between Two Active Pharmaceutical Ingredient (API) Sources of Opicapone (OPC)
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: DRUG: 50 mg BIA 9 1067|DRUG: 25 mg BIA9 1067|DRUG: 50 mg Ongentys|DRUG: 25 mg Ongentys
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Exploratory Muscle Biopsy Assessment Study in Patients With Late-Onset Pompe Disease Treated With Alglucosidase Alfa
Status: COMPLETED
Conditions: Pompe Disease (Late-Onset)|Glycogen Storage Disease Type II (GSD II)|Glycogenesis 2 Acid Maltase Deficiency
Interventions: BIOLOGICAL: Alglucosidase Alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Simplified Tai Chi for Reducing Fibromyalgia Pain
Status: COMPLETED
Conditions: Fibromyalgia
Interventions: BEHAVIORAL: 8-form Yang-style Tai chi|BEHAVIORAL: Group education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Galactose - the Ideal Carbohydrate Supplement for Exercise in Type 1 Diabetes
Status: RECRUITING
Conditions: Type1diabetes|Hypoglycemia|Hyperglycemia
Interventions: OTHER: 1-hour cycling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Phase 2 Study of Amrubicin in Relapsed or Refractory Thymic Malignancies
Status: COMPLETED
Conditions: Thymoma|Thymus Cancer|Thymic Carcinoma
Interventions: DRUG: Amrubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study to Evaluate Safety, Tolerability, and PK of DA-7503 in Healthy Adult and Elderly Participants
Status: NOT_YET_RECRUITING
Conditions: Healthy
Interventions: DRUG: DA-7503 Single dose|DRUG: DA-7503 Multiple dose|DRUG: Placebo Single dose|DRUG: Placebo Multiple dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Irinotecan and Thalidomide in Treating Patients With Advanced Solid Tumors
Status: COMPLETED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: irinotecan hydrochloride|DRUG: thalidomide|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Cabozantinib (XL184) Versus Prednisone in Men With Metastatic Castration-resistant Prostate Cancer Previously Treated With Docetaxel and Abiraterone or MDV3100
Status: COMPLETED
Conditions: Prostate Cancer|Castration Resistant Prostate Cancer|Pain|Prostatic Neoplasms
Interventions: DRUG: cabozantinib|DRUG: prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Diabetes Prevention Program Outcomes Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Diabetes Mellitus|Cancer|CVD
Interventions: BEHAVIORAL: DPPOS Group Lifestyle|DRUG: Metformin|BEHAVIORAL: DPPOS Boost Lifestyle|BEHAVIORAL: Intensive Lifestyle Group Session
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Dexmedetomidine and Fentanyl Versus Midazolam and Remifentanil for Sedation in Patients Undergoing Ablation Procedures
Status: TERMINATED
Conditions: Tachyarrhythmia
Interventions: DRUG: Dexmedetomidine group|DRUG: Remifentanil Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Vibrating Vaginal Balls After Childbirth
Status: COMPLETED
Conditions: Pelvic Floor Health After Childbirth
Interventions: DEVICE: Laselle Kegel Exerciser|BEHAVIORAL: Pelvic floor muscle exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: A Research Study Looking Into Blood Levels of the Medicine NNC0487-0111 in the Body and How Well it is Tolerated in Participants With Reduced Kidney Function and Normal Kidney Function
Status: NOT_YET_RECRUITING
Conditions: Diabetes Mellitus, Type 2|Obesity|Overweight
Interventions: DRUG: NNC0487-0111
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Routine Evaluation of the Social Determinants of Health in Oncology: User-centered Resource Coordination and Engagement
Status: COMPLETED
Conditions: Breast Cancer|Lung Cancer|Gastrointestinal Cancer
Interventions: OTHER: Resource Matching|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Trial of Donor Lymphocyte Infusion (DLI) and Activated DLI Following Relapse After Allogeneic Stem Cell Transplant
Status: TERMINATED
Conditions: Chronic Myelogenous Leukemia|Acute Myelogenous Leukemia|Acute Lymphoblastic Leukemia|Myelodysplastic Syndrome|Non-Hodgkin's Lymphoma|Hodgkin's Disease|Multiple Myeloma|Chronic Lymphocytic Leukemia
Interventions: BIOLOGICAL: CD3/CD28 Activated T cells|BIOLOGICAL: CD3/CD28 Activated T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Retreatment With Rituximab in Patients With Rheumatoid Arthritis Receiving Background Methotrexate
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: placebo|DRUG: rituximab|DRUG: methotrexate|DRUG: folate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Promoting Equity for Cancer Screening and Follow-up
Status: WITHDRAWN
Conditions: Colorectal (Colon or Rectal) Cancer
Interventions: OTHER: IVR Reminder|OTHER: Phone call from research team|OTHER: EHR Portal message
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Embracing Morning BReakfast and Activity for Classroom Engagement
Status: NOT_YET_RECRUITING
Conditions: Child Development
Interventions: BEHAVIORAL: High Protein Breakfast|BEHAVIORAL: Morning Exercise|BEHAVIORAL: High Carb Breakfast
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Evaluation of a Daily Oral Care Lozenge on Oral Health and Quality of Life in Older Adults
Status: UNKNOWN
Conditions: Oral Health
Interventions: DIETARY_SUPPLEMENT: PTx800 lozenges|DIETARY_SUPPLEMENT: Placebo control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Efficacy Of Proinflammatory Cytokines in The Primary Molar Pulpotomy
Status: COMPLETED
Conditions: Pulp Disease, Dental
Interventions: PROCEDURE: PULPOTOMY TREATMENT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Bioequivalence of a Fixed Dose Combination Tablet Linagliptin/Pioglitazone Compared With Its Mono-components
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Linagliptin + Pioglitazone|DRUG: Linagliptin + Pioglitazone|DRUG: Linagliptin/Pioglitazone|DRUG: Linagliptin/Pioglitazone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ATI-501 Oral Suspension Compared to Placebo in Subjects With Alopecia Areata, Alopecia Universalis or Alopecia Totalis
Status: COMPLETED
Conditions: Alopecia
Interventions: DRUG: ATI-501 400mg BID (Low dose)|DRUG: ATI-501 600mg BID (Mid dose)|DRUG: ATI-501 800mg BID (High dose)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Comparing of Long Bout and Short Bouts of Similar Volume of Walking in Obese on Weight Loss During a Weight Loss Program
Status: COMPLETED
Conditions: Obesity|Overweight
Interventions: BEHAVIORAL: Diet+ short term versus long -term physical activity
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Multiday Fully Closed Loop Insulin Delivery in Monitored Outpatient Conditions
Status: UNKNOWN
Conditions: To Demonstrate That the Closed Loop System Can be Used Safely Over a Few Consecutive Days.|To Assess Effectiveness in Maintaining Patients' Glucose Levels in the Target Range of 70 to 180 mg/dl, Measured by Blood Glucose Sensor.|To Evaluate the User Experience With a Closed Loop System
Interventions: DEVICE: Automated Ambulatory Glycemic Controller (AAGC)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Omega-3 Fatty Acids in Tourette's Disorder
Status: COMPLETED
Conditions: Tourette's Disorder
Interventions: DRUG: Omega-3 Fatty Acids|DRUG: Olive oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Pharmacogenetic of Ibuprofen After Lower Third Molar Surgeries
Status: UNKNOWN
Conditions: Pain|Other Surgical Procedures|Impacted Third Molar Tooth
Interventions: DRUG: Ibuprofen 600 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Sedation During Microelectrode Recordings Before Deep Brain Stimulation for Movement Disorders.
Status: UNKNOWN
Conditions: Movement Disorders|Parkinson Disease|Parkinsonian Disorders|Dystonia|Tourette Syndrome
Interventions: PROCEDURE: Sedation with IV propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: COmparison of Xience PrimE Versus REsolute Integrity in Diabetes or Small Vessel Disease
Status: UNKNOWN
Conditions: Angioplasty, Balloon, Coronary
Interventions: PROCEDURE: percutaneous coronary intervention using drug eluting stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Integrative Medicine Impact on Frontline COVID-19 Personnel Wellbeing
Status: COMPLETED
Conditions: Wellbeing of Healthcare Providersin Frontline COVID-19 Departments
Interventions: OTHER: Complementary Integrative Medicine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Presternal Magnesium With Bupivacain Versus Bupivacain Only for Postoperative Pain Relief in Open Heart Surgery
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: Bupivacaine magnesium|DRUG: Bupivacaine only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: PRV-015 in Gluten-free Diet Non-responsive Celiac Disease
Status: COMPLETED
Conditions: Celiac Disease
Interventions: BIOLOGICAL: PRV-015|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: P6 Acupressure Band for Prevention of Postoperative Nausea and Vomiting in Children
Status: COMPLETED
Conditions: Postoperative Nausea and Vomiting|Postoperative Nausea and Vomiting \(PONV\)Acuppressure
Interventions: DEVICE: Accupressure band
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Kiwifruit, Prunes, & Fiber for Abdominal and Bowel Symptoms in US Patients With Chronic Constipation
Status: COMPLETED
Conditions: Chronic Constipation
Interventions: DIETARY_SUPPLEMENT: Kiwifruit|DIETARY_SUPPLEMENT: Fiber|DIETARY_SUPPLEMENT: Prunes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Efficacy and Safety of the Lower Dose of Bortezomib Plus Busulfan and Melphalan as a Conditioning Regimen in Patients With Multiple Myeloma Undergoing Autologous Peripheral Blood Stem Cell Transplantation- KMM103 Study
Status: UNKNOWN
Conditions: Multiple Myeloma Patients Who Candidate for Autologous Peripheral Blood Stem Cell Transplantation
Interventions: DRUG: Bortezomib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Relationship Between Lidocaine and Serum Orphanin FQ (N/OFQ)
Status: RECRUITING
Conditions: Stress Reaction
Interventions: DRUG: Lidocaine|DRUG: 0.9%NaCl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Novel INXN-4001 Triple Effector Plasmid in Heart Failure
Status: COMPLETED
Conditions: Heart Failure|Cardiovascular Diseases|Heart-Assist Device
Interventions: BIOLOGICAL: INXN-4001
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BMAC in Severe Hip or Knee Osteoarthritis Awaiting Arthroplasty
Status: WITHDRAWN
Conditions: Osteoarthritis, Knee|Osteoarthritis, Hip
Interventions: BIOLOGICAL: Bone Mineral Aspirate Concentrate (BMAC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Diode Laser Therapy As An Adjunct To Scaling And Root Planing
Status: COMPLETED
Conditions: Chronic Periodontitis
Interventions: PROCEDURE: Ultrasonic Scaling and root planing|PROCEDURE: 980 nm diode laser irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bone Marrow as an Alternative Site for Islet Transplantation
Status: COMPLETED
Conditions: Type 1 Diabetes|Postpancreatectomy Hyperglycemia
Interventions: PROCEDURE: Intra bone marrow islet infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Efficacy Trial in the Research Area of Gastrointestinal Health & Bloating
Status: ACTIVE_NOT_RECRUITING
Conditions: Gastrointestinal Dysfunction
Interventions: DIETARY_SUPPLEMENT: Active|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 3 Study to Evaluate the Efficacy and Safety of Pergoveris® in Assisted Reproductive Technology (ESPART)
Status: COMPLETED
Conditions: Infertility
Interventions: DRUG: Pergoveris®|DRUG: GONAL-f®|DRUG: Recombinant human chorionic gonadotrophin (r-hCG)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of NVA237 on Exercise Endurance in Patients With Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: NVA237|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: EASI Access II --- Follow-up Study to the EASI Access Trial
Status: COMPLETED
Conditions: Disaster Medicine|Difficult Intravenous Access|Dehydration
Interventions: DRUG: Human recombinant hyaluronidase (HRH)|PROCEDURE: Enzymatically Augmented Subcutaneous Infusion (EASI) line placement
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Day-care Versus Overnight-stay Laparoscopic Cholecystectomy Randomized Controlled Trial.
Status: UNKNOWN
Conditions: Cholelithiasis
Interventions: PROCEDURE: Laparoscopic Cholecystectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Extension Study to Evaluate the Long-Term Safety and Tolerability of JNJ-54861911 in Participants in the Early Alzheimer's Disease Spectrum
Status: TERMINATED
Conditions: Alzheimer Disease
Interventions: DRUG: JNJ-54861911, 10 mg|DRUG: JNJ-54861911, 25 mg|DRUG: Placebo|DRUG: JNJ-54861911, 5 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Monocentric Prospective Pilot Study Evaluating the Value of Indocyanine Green (ICG, Indocyanine Green) During a Surgical Resection of Cancerous Lesions Peritoneal Colorectal Origin.
Status: COMPLETED
Conditions: Colorectal Cancer Metastatic
Interventions: DRUG: indocyanine green
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase 1 Study To Evaluate the Safety of Migalastat Hydrochloride Given Intravenously to Healthy Volunteers
Status: COMPLETED
Conditions: Fabry Disease
Interventions: DRUG: IV migalastat HCl|DRUG: IV placebo|DRUG: oral migalastat HCl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Drug-Drug Interaction Study of TAK-788 and Midazolam in Participants With Advanced Non-small Cell Lung Cancer (NSCLC)
Status: COMPLETED
Conditions: Carcinoma, Non-Small-Cell Lung|Lung Neoplasms
Interventions: DRUG: Midazolam|DRUG: TAK-788
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Cisplatin and Irinotecan Followed by Carboplatin, Etoposide, and Radiation Therapy in Treating Patients With Limited-Stage Small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DRUG: carboplatin|DRUG: cisplatin|DRUG: etoposide|DRUG: irinotecan hydrochloride|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral Omadacycline vs. Oral Linezolid for the Treatment of ABSSSI
Status: COMPLETED
Conditions: Bacterial Infections|Skin Structures and Soft Tissue Infections
Interventions: DRUG: Omadacycline|DRUG: Linezolid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Simultaneous Multinuclear Metabolic MRI in Newly Diagnosed or Recurrent Glioma
Status: RECRUITING
Conditions: Glioma|Malignant Glioma|Recurrent Glioma|Recurrent Malignant Glioma
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Diagnostic Imaging|PROCEDURE: Magnetic Resonance Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Onset Motor Complications Using REQUIP CR (Ropinirole Controlled-release) As Add-on Therapy To L-dopa In Parkinson's
Status: COMPLETED
Conditions: Parkinson's Disease|Parkinson Disease|Dyskinesias
Interventions: DRUG: ropinirole controlled-release (REQUIP CR) for RLS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: New Antiviral Drugs for Treatment of COVID-19
Status: UNKNOWN
Conditions: COVID|Drug Effect
Interventions: DRUG: Treatment group: will receive a combination of Nitazoxanide, Ribavirin and Ivermectin for a duration of seven days :
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety of Lactobacillus Reuteri (L. Reuteri) in Healthy Adults
Status: COMPLETED
Conditions: Colic|Gastrointestinal Tract Infections
Interventions: BIOLOGICAL: L. reuteri|BIOLOGICAL: Sunflower Oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Low-level Laser Therapy on Salivary Flow, pH and Quality of Life in Irradiated Oropharyngeal Cancer Patients
Status: COMPLETED
Conditions: Xerostomia
Interventions: RADIATION: Low-Level Laser Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Vitamin D Supplementation on Reported Rates of Taxane-Induced Neuropathy
Status: SUSPENDED
Conditions: Neuropathic Pain
Interventions: DRUG: Ergocalciferol Capsules|DIETARY_SUPPLEMENT: Cholecalciferol Capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Sunvozertinib Plus Anlotinib as 1L Treatment in EGFR-Sensitive Mutations Combined With Co-Mutations Advanced NSCLC
Status: NOT_YET_RECRUITING
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: sunvozertinib in combination with Anlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Filtered Sunlight Phototherapy to Treat Significant Jaundice: Safety and Efficacy in Neonates
Status: COMPLETED
Conditions: Jaundice, Neonatal
Interventions: DEVICE: Filtered-sunlight phototherapy|DEVICE: Intensive phototherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessing the Effectiveness of a Multiple-micronutrient Fortified Maize Pap on the Nutrient Status of Nigerian School-aged Children
Status: ENROLLING_BY_INVITATION
Conditions: Nutrient Deficiency|Iron Deficiencies
Interventions: DIETARY_SUPPLEMENT: Multiple micronutrient fortified maize with milk
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Impact of 80 W KTP Laser Vaporization Prostatectomy on Severity of Obstruction in Benign Prostatic Hyperplasia
Status: COMPLETED
Conditions: Lower Urinary Tract Symptoms|Benign Prostatic Hyperplasia
Interventions: PROCEDURE: photoselective vaporization prostatectomy (PVP)|PROCEDURE: Transurethral resection of the prostate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT