pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Airway Effects of PEEP During Anesthesia Induction.
Status: UNKNOWN
Conditions: Airway Management|Positive End Expiratory Pressure|Mask-ventilation|Anesthesia Induction
Interventions: PROCEDURE: PEEP-level, driving pressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Dose Escalation/Expansion Study of ERAS-601 in Patients With Advanced or Metastatic Solid Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced or Metastatic Solid Tumors
Interventions: DRUG: ERAS-601|DRUG: Cetuximab|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MEK162 in Combination With Imatinib Mesylate in Patients With Untreated Advanced Gastrointestinal Stromal Tumor (GIST)
Status: ACTIVE_NOT_RECRUITING
Conditions: Gastrointestinal Stromal Tumor (GIST)
Interventions: DRUG: MEK162|DRUG: Imatinib Mesylate (Gleevec®; STI571; NSC #716051)|OTHER: Blood draws|PROCEDURE: biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Chemoattractant Receptor-homologous Molecule Expressed on T Helper Type 2 (CRTh2) Antagonist AZD1981 in Chronic Idiopathic Urticaria (CIU) Antihistamines
Status: COMPLETED
Conditions: Chronic Idiopathic Urticaria
Interventions: DRUG: AZD1981|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lenvatinib in Combination With Carboplatin Pemetrexed and Pembrolizumab for NSCLC With EGFR Mutations
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-squamous Non-small-cell Lung Cancer|EGFR Activating Mutation
Interventions: DRUG: Pembrolizumab|DRUG: Lenvatinib|DRUG: Carboplatin|DRUG: Pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Genetic Polymorphisms of Vasoactive Peptides on the Prognosis of Patients With COVID19
Status: UNKNOWN
Conditions: Sars-CoV-2 Infection
Interventions: OTHER: Analysis of genetic polymorphisms of vasoactive peptides in COVID-19
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effects of Antibiotic Prophylaxis on the Healing Parameters Following Surgical Crown Lengthening
Status: NOT_YET_RECRUITING
Conditions: Tooth Diseases|Tooth Wear
Interventions: PROCEDURE: Surgical crown lengthening|DRUG: Augmentin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of GSK Biologicals' Tdap Candidate Vaccine Administered as a Booster (6th Dose) in Terms of Immunogenicity and Safety to Children and Adolescents Previously Vaccinated With Five Doses of an Acellular Pertussis-containing Vaccine.
Status: COMPLETED
Conditions: Acellular Pertussis|Diphtheria|Tetanus
Interventions: BIOLOGICAL: Prophylaxis: Diphtheria, tetanus and pertussis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Tolerance and Benefits of Mandibular Advanced Device for Snoring and Sleep Apnea in Oropharyngeal Cancer.
Status: RECRUITING
Conditions: Oral Cancer|Pharynx Cancer|Sleep Apnea|Snoring|Oral Squamous Cell Carcinoma
Interventions: DEVICE: Ronco-Onco and MAD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Augmented BLAdder NecK rEconstruction Trial for Improved Urinary Function After Radical Prostatectomy
Status: TERMINATED
Conditions: Prostate Cancer|Urinary Incontinence|Surgery
Interventions: PROCEDURE: Augmented Bladder Neck Reconstruction|PROCEDURE: Standard Bladder Neck Reconstruction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Systemic Chemotherapy Plus Lenvatinib and Toripalimab for HCC With Extrahepatic Metastasis
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma
Interventions: PROCEDURE: Systemic chemotherapy|DRUG: Lenvatinib|DRUG: Toripalimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nitric Oxide Donor Isosorbide Mono Nitrate for Induction of Labor With Pre-labor Rupture of Membranes
Status: COMPLETED
Conditions: Induction of Labor Affected Fetus / Newborn|Rupture of Membranes Prior to Onset of Labor
Interventions: DRUG: isosorbide mononitrate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Does Serotonin System Stimulation Increase Pro-social Behavior? - A Comparative Pharmacological Neuroscientific Study in Healthy Humans
Status: RECRUITING
Conditions: Healthy
Interventions: DRUG: Psilocybin|DRUG: 3,4 Methylenedioxymethamphetamine|DRUG: Methylphenidate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Are the Fried Criteria Predictive of a Functional Decline in Older People With Solid Malignant Tumors?
Status: COMPLETED
Conditions: Elderly Patients With a Solid Tumor
Interventions: OTHER: Quality of life evaluation|OTHER: Functional decline assessment|OTHER: Physical decline assessment|OTHER: Cognitive decline assessment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The (HD)IVACOV Trial (The High-Dose IVermectin Against COVID-19 Trial)
Status: UNKNOWN
Conditions: Covid19
Interventions: DRUG: Ivermectin 0.6mg/kg/day|DRUG: Ivermectin 1.0mg/kg/day|DRUG: Placebo|DRUG: Hydroxychloroquine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Cyclosporine Therapy on Gene Expression in Patients With Large Granular Lymphocyte Leukemia
Status: TERMINATED
Conditions: Large Granular Lymphocytic Leukemia|LGL Leukemia
Interventions: DRUG: Cyclosporine|GENETIC: Gene expression analysis|GENETIC: Microarray analysis|OTHER: Laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 2, Muti-Center Study of Repeat Dosing of Squaric Acid Dibutyl Ester in Subjects With Herpes Labialis
Status: TERMINATED
Conditions: Herpes Labialis|HSV
Interventions: DRUG: Squaric Acid Dibutyl Ester
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Clinical Investigation to Assess a New Artificial Urinary Sphincter to Treat Urinary Incontinence in Women
Status: RECRUITING
Conditions: Urinary Incontinence,Stress
Interventions: DEVICE: UroMems artificial urinary sphincter
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial to Promote Recovery From COVID-19 With Endocrine Therapy
Status: WITHDRAWN
Conditions: COVID-19|SARS-CoV 2
Interventions: DRUG: Bicalutamide 150 Mg Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Intramyometrial Injection of Terlipressin Versus Intramyometrial Injection of Carbitocin on Hemoglobin and Blood Loss During Laparoscopic Myomectomy Operations
Status: RECRUITING
Conditions: Laparoscopic Myomectomy
Interventions: DRUG: Terlipressin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effectiveness Study of Short Course of Magnesium Sulfate for Severe Preeclamsia
Status: COMPLETED
Conditions: Severe Preeclampsia
Interventions: DRUG: Magnesium sulfate 12 hours|DRUG: Magnesium sulfate 24 hours
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial of Panobinostat and Trastuzumab for Adult Female Patients With HER2 Positive Metastatic Breast Cancer (MBC) Whose Disease Has Progressed on or After Trastuzumab
Status: TERMINATED
Conditions: Breast Cancer
Interventions: DRUG: Panobinostat|DRUG: Trastuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HCT Versus CT in Elderly AML
Status: TERMINATED
Conditions: Acute Myeloid Leukemia
Interventions: PROCEDURE: hematopoietic cell transplantation|DRUG: Non-Transplant treatment approach for consolidation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study Of Gabapentin Between Tablet And Liquid Formulation And The Food Effect Study Of Liquid Formulation
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Gabapentin|DRUG: Gabapentin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hand Holding During Light Sedation for Minimally Invasive Spine Surgery Improves Outcomes
Status: UNKNOWN
Conditions: Spine|Minimally Invasive
Interventions: BEHAVIORAL: Intraoperative Hand Held
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Bacillus of Calmette and Guerin (BCG) Versus Gemcitabine For Intravesical Therapy In High Risk Superficial Bladder Cancer
Status: COMPLETED
Conditions: Bladder Cancer
Interventions: DRUG: BCG|DRUG: gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Controlled Trial to Evaluate Amifampridine Phosphate in Spinal Muscular Atrophy Type 3 Patients
Status: COMPLETED
Conditions: Muscular Atrophy, Spinal
Interventions: DRUG: Amifampridine Phosphate|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sarcopenia and Related Factors in Lipedema
Status: RECRUITING
Conditions: Lipedema|Sarcopenia|Musculoskeletal Diseases
Interventions: DIAGNOSTIC_TEST: STAR-Sonographic Thigh Adjustment Ratio|DIAGNOSTIC_TEST: Hand Grip Strength|DIAGNOSTIC_TEST: Chair Stand Test|DIAGNOSTIC_TEST: 6 Meter Gait Speed
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Health Effects of SLT, Cigarette Smoking, and New Tobacco Products
Status: COMPLETED
Conditions: Nicotine Dependence
Interventions: DRUG: Nicotine gum and lozenge|OTHER: Taboka|OTHER: Camel Snus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long-term Resveratrol and Metabolism
Status: COMPLETED
Conditions: Pre-diabetes
Interventions: DIETARY_SUPPLEMENT: resveratrol|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Immunotherapy of Tumor With Autologous Tumor Derived Heat Shock Protein gp96
Status: UNKNOWN
Conditions: Liver Cancer|Pancreatic Adenocarcinoma
Interventions: BIOLOGICAL: autologous gp96 vaccination
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of Autologous Adipose Tissue Derived Stromal Cell Therapy for Ischemic Heart Failure
Status: UNKNOWN
Conditions: Ischemic Heart Failure
Interventions: BIOLOGICAL: adipose tissue derived stromal cells dosage
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Treat Subjects With Telaprevir, Ribavirin, and Peginterferon Who Are Coinfected With HIV and Hepatitis C Virus (HCV)
Status: TERMINATED
Conditions: Hepatitis C
Interventions: DRUG: Telaprevir|DRUG: Ribavirin|BIOLOGICAL: Pegylated Interferon Alfa-2a|DRUG: Highly Active Antiretroviral Therapy (HAART)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rehabilitation of Executive Functioning in Veterans With PTSD and Mild TBI
Status: COMPLETED
Conditions: Post Traumatic Stress Disorder|Mild Traumatic Brain Injury, Concussion
Interventions: BEHAVIORAL: GOALS (Goal-Oriented Attentional Regulation)|BEHAVIORAL: EDU (Brain Health Education)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trauma-adapted Yoga in Child & Adolescent Psychiatry.
Status: NOT_YET_RECRUITING
Conditions: ADHD|PTSD|Quality of Life|Self-Control|Pain|Affect
Interventions: OTHER: Trauma-adapted yoga
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Long-term Follow-up of Participants With Cerebral Adrenoleukodystrophy Who Were Treated With Lenti-D Drug Product
Status: ACTIVE_NOT_RECRUITING
Conditions: Cerebral Adrenoleukodystrophy (CALD)|Adrenoleukodystrophy (ALD)|X-Linked Adrenoleukodystrophy (X-ALD)
Interventions: GENETIC: No interventional drug product utilized in this follow-up study
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Evaluate the Discontinuation Effect of Clopidogrel After Drug Eluting Stent Implantation in Non-diabetic Patients
Status: COMPLETED
Conditions: Antiplatelet Aggregation
Interventions: PROCEDURE: Blood Collection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Therapy Protocol Acute Lymphoblastic Leukemia Stem Cell Transplantation International
Status: COMPLETED
Conditions: Acute Lymphoblastic Leukemia
Interventions: PROCEDURE: Transplantation with Stem Cells from Umbilical Cord
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Group Therapy for Nicotine Dependence: Mindfulness and Smoking
Status: COMPLETED
Conditions: Smoking|Tobacco Use Cessation
Interventions: BEHAVIORAL: MBAT Group Therapy|DRUG: Nicotine|BEHAVIORAL: Group Therapy|BEHAVIORAL: Individual Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Covert-saccades, Dynamic Visual Acuity and Quality of Life
Status: COMPLETED
Conditions: Vestibular Diseases
Interventions: OTHER: Head Impulse Tests|OTHER: Dynamic visual acuity Test (DVAT)|OTHER: VEMPs & VEMPo|OTHER: Dizziness Handicap Inventory|OTHER: Oscillopsia severity questionnaire
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Brain Processes Underlying Speech Motor Learning and Speech Production
Status: RECRUITING
Conditions: Healthy Adults
Interventions: BEHAVIORAL: Effects of speech variability on speech motor learning|BEHAVIORAL: Effects of error-detection training on speech motor learning|BEHAVIORAL: Contributions of error awareness to speech motor learning|BEHAVIORAL: Enhancing auditory-to-motor mapping with augmented visual feedback|BEHAVIORAL: Effects of enhanced auditory-motor awareness on speech motor learning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Determination and Comparison of Short-term Effectiveness of Three Methods Used for Recognition of Arrhythmias in People With Different Degrees of Medical Training (Advanced Life Support Workshop Participants-ALS): Randomized Controlled Educational Experiment.
Status: COMPLETED
Conditions: Arrhythmias
Interventions: OTHER: Arrhythmia diagnosis with the 10 steps method|OTHER: Arrhythmia diagnosis with the 6 steps method|OTHER: Arrhythmia diagnosis with the 4 steps method
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Reamed Nailing Versus Taylor Spatial Frame in Tibia Shaft Fractures
Status: COMPLETED
Conditions: Tibial Fractures
Interventions: DEVICE: Taylor Spatial Frame|DEVICE: Intramedullary nail
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Accelerated rTMS in Gambling Disorder: a Multicentric, Randomized, Sham-controlled Trial
Status: NOT_YET_RECRUITING
Conditions: Gambling|Gambling Disorder|Gambling, Pathological|Gambling Problem
Interventions: DEVICE: Accelerated repetitive Transcranial Magnetic Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Jackson Heart Study Women's Hypertension Study
Status: NOT_YET_RECRUITING
Conditions: Hypertension
Interventions: BEHAVIORAL: MIND-BP|BEHAVIORAL: BOOST
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study to Determine the Dose and Safety of Asciminib in Pediatric Patients With Chronic Myeloid Leukemia
Status: RECRUITING
Conditions: Myeloid Leukemia, Philadelphia Positive
Interventions: DRUG: Asciminib Pediatric formulation group|DRUG: Asciminib Adult formulation group
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity Study of Candidate HIV-1 Vaccine Given to Healthy Infants Born to HIV-1/2-uninfected Mothers
Status: COMPLETED
Conditions: HIV-1|HIV Infections
Interventions: BIOLOGICAL: MVA.HIVA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics (PK) of Oral TAK-994 in an Acute Sleep Phase Delay Paradigm in Healthy Male Participants
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: TAK-994|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Albumin-Bound Paclitaxel Followed by Epirubicin in Combination With Cyclophosphamide in Triple Negative Breast Cancer
Status: UNKNOWN
Conditions: Triple Negative Breast Cancer
Interventions: DRUG: Chemotherapeutic Agent
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Tezepelumab (AMG 157) in Healthy Adults
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Placebo|DRUG: Tezepelumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Effect of Dialyzable Leukocyte Extract in Suspected or Confirmed Cases of COVID-19 (FUTURE-T)
Status: UNKNOWN
Conditions: COVID-19|SARS-CoV-2 Infection
Interventions: DRUG: Dialyzable Leukocyte Extract|DRUG: Placebo oral
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Artificial Intelligence-based Early Screening of Pancreatic Cancer and High Risk Tracing (ESPRIT-AI)
Status: RECRUITING
Conditions: Pancreatic Cancer|Diabetes|Familial Pancreatic Cancer|Pancreatic Cystic Neoplasm|Chronic Pancreatitis|Hereditary Pancreatitis
Interventions: DIAGNOSTIC_TEST: high-resolution MRI/CT examinations
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Combining Motor Imagery With Action Observation Does Not Lead to a Greater Autonomic Response Than Motor Imagery Alone During Simple and Functional Movements: a Randomized Controlled Trial.
Status: COMPLETED
Conditions: Autonomic Nervous System
Interventions: BEHAVIORAL: Motor Imagery|BEHAVIORAL: Action Observation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Assessment of Probe Based Confocal Laser Endo-microscopy for In-vivo Diagnosis of Peripheral Lung Nodules and Masses.
Status: COMPLETED
Conditions: Pulmonary Nodule Persistent|Malignant Neoplasm of the Respiratory System|Benign Neoplasms of the Respiratory System
Interventions: DEVICE: confocal endo-microscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparing Ginkgo Biloba Pills and Placebo in the Treatment of Coronary Heart Disease With Impaired Glucose Regulation
Status: UNKNOWN
Conditions: Randomized Controlled Trial|Ginkgo Biloba Extract
Interventions: DRUG: Ginkgo biloba pills|DRUG: placebo pills
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Middle and High School Students' Reactions to a Health Interactive Website: ASPIRE Reactions
Status: COMPLETED
Conditions: Tobacco Use Cessation|Tobacco Prevention
Interventions: BEHAVIORAL: Surveys|BEHAVIORAL: ASPIRE Website|BEHAVIORAL: ASPIRE Text-Based Website|BEHAVIORAL: Follow Up Survey
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: GD-11 for Injection in the Treatment of Acute Ischemic Stroke
Status: RECRUITING
Conditions: Acute Ischemic Stroke
Interventions: DRUG: GD-11 for injection test group|DRUG: Placebo control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Diacutaneous Fibrolysis and Subacromial Syndrome
Status: COMPLETED
Conditions: Subacromial Impingement Syndrome
Interventions: OTHER: Actual Diacutaneous Fibrolysis|OTHER: Placebo Diactuaneous Fibrolysis|OTHER: Protocolized physiotherapeutic Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Vitamin B6 and Magnesium- A Clinical Trial on ASD Patients
Status: UNKNOWN
Conditions: Autism Spectrum Disorder
Interventions: COMBINATION_PRODUCT: Magnesium and Vitamin B6
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pharmacokinetics, Efficacy and Safety of the 304 Injection
Status: UNKNOWN
Conditions: CD20 Positive B Cell NHL
Interventions: DRUG: 304 injection|DRUG: rituximab injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Yoga to Prevent Mobility Limitations in Older Adults
Status: COMPLETED
Conditions: Aging|Mobility Limitation|Sedentary Lifestyle
Interventions: BEHAVIORAL: Yoga Intervention|BEHAVIORAL: Healthy Aging Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Notification of Incidental Coronary Artery Calcium in Patients With Atherosclerotic Cardiovascular Disease (NOTIFY-ASCVD)
Status: NOT_YET_RECRUITING
Conditions: ASCVD|Coronary Artery Calcification
Interventions: OTHER: Notification of patients and clinicians
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of RO7049665 in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: BIOLOGICAL: RO7049665|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Confirm of the Safety and Tolerability of Brincidofovir in Subjects With BK Virus Infection (Viremia) After Kidney Transplantation
Status: RECRUITING
Conditions: BK Virus Infection|Nephropathy|Kidney Transplantation
Interventions: DRUG: Brincidofovir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clevidipine (Cleviprex®) Compared With Urapidil (Ebrantil®)
Status: WITHDRAWN
Conditions: Nontraumatic Intracerebral Hemorrhage, Multiple Localized
Interventions: DRUG: Clevidipine|DRUG: Urapidil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Studying the Effects of Administration of Polyunsaturated Fatty Acids (PUFAS) of Omega-3 Series in Nicotine Dependence
Status: COMPLETED
Conditions: Tobacco Dependence|Nicotine Dependence
Interventions: DRUG: Omega 3|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Safety and Efficacy of Intrathecal Injection of RJK002 in Patients With Amyotrophic Lateral Sclerosis
Status: NOT_YET_RECRUITING
Conditions: Amyotrophic Lateral Sclerosis Als
Interventions: DRUG: RJK002 Intrathecal injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Acute Nitrate Supplementation on Vascular Function in Hispanic, Black and White Population
Status: RECRUITING
Conditions: Healthy Adults
Interventions: DIETARY_SUPPLEMENT: Beetroot juice|DIETARY_SUPPLEMENT: Placebo drink
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Laser Versus Physiotherapy in Management of Bruxism in Children: RCS
Status: COMPLETED
Conditions: Bruxism
Interventions: DEVICE: Laser acupuncture|BEHAVIORAL: Modified physical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PET Study With 11 C-PIB to Evaluate Amyloid Protein Deposits in Mild Cognitive Disorder, Alzheimer's Disease and Early Frontotemporal Degeneration.
Status: COMPLETED
Conditions: Alzheimer Disease
Interventions: DIAGNOSTIC_TEST: PET/CT with 11C-PiB
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Guanidinoacetic Acid Loading for Chronic Fatigue Syndrome
Status: COMPLETED
Conditions: Chronic Fatigue Syndrome
Interventions: DIETARY_SUPPLEMENT: Guanidinoacetic acid|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phase 2b Booster Vaccination (TURKOVAC) Against COVID-19
Status: COMPLETED
Conditions: COVID-19|Sars-CoV-2 Infection
Interventions: BIOLOGICAL: TURKOVAC-Dollvet|BIOLOGICAL: TURKOVAC-Koçak
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Confocal Endoscopic Microscopy for Detection of Early Stage Gastric Cancer in Subjects With Hereditary Diffuse Gastric Cancer Syndrome
Status: COMPLETED
Conditions: Gastric Cancer|Gastric Neoplasms
Interventions: DEVICE: Endoscope+Cellvizio(R) 100 microscope
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Donor Stem Cell Transplant or Donor White Blood Cell Infusions in Treating Patients With Hematologic Cancer
Status: TERMINATED
Conditions: Chronic Myeloproliferative Disorders|Leukemia|Lymphoma|Multiple Myeloma and Plasma Cell Neoplasm|Myelodysplastic Syndromes|Myelodysplastic/Myeloproliferative Neoplasms|Unusual Cancers of Childhood
Interventions: BIOLOGICAL: anti-thymocyte globulin|BIOLOGICAL: filgrastim|DRUG: busulfan|DRUG: carmustine|DRUG: cyclophosphamide|DRUG: cyclosporine|DRUG: cytarabine|DRUG: etoposide|DRUG: fludarabine phosphate|DRUG: melphalan|DRUG: methotrexate|DRUG: methylprednisolone|DRUG: mycophenolate mofetil|DRUG: tacrolimus|PROCEDURE: peripheral blood stem cell transplantation|PROCEDURE: umbilical cord blood transplantation|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mifepristone and Misoprostol for 2nd Trimester Termination of Pregnancy in Burkina Faso
Status: UNKNOWN
Conditions: Medical; Abortion, Fetus
Interventions: DRUG: Mifepristone|DRUG: Misoprostol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatments of Mal de Debarquement Syndrome (MdDS) by Habituation of Velocity Storage
Status: COMPLETED
Conditions: Mal de Debarquement Syndrome (MdDS)
Interventions: DEVICE: re-adaptation of the vestibulo-ocular reflex|DEVICE: Habituation of velocity storage of the vestibulo-ocular reflex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Physical Activities by Technology Help (PATH)
Status: COMPLETED
Conditions: Breast Cancer|Prostate Cancer|Lung Cancer|Colorectal Cancer|Cervical Cancer|Oral Cancer
Interventions: BEHAVIORAL: Mycoach Smart Text|BEHAVIORAL: MyCoach on Amazon Alexa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Clinical Study Using Autologous Bone Marrow Stem Cell for Diabetes Related Vascular Complications
Status: UNKNOWN
Conditions: Peripheral Vascular Disease|Ischemia|Diabetic Foot
Interventions: BIOLOGICAL: mesenchymal stem cells|BIOLOGICAL: saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Examine the Safety, Pharmacokinetics and Pharmacodynamics of AMG 403 in Healthy Subject
Status: COMPLETED
Conditions: Chronic Pain
Interventions: DRUG: AMG 403|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate ASP8232 in Reducing Central Retinal Thickness in Subjects With Diabetic Macular Edema (DME)
Status: COMPLETED
Conditions: Diabetes Mellitus|Diabetic Macular Edema
Interventions: DRUG: ASP8232|DRUG: ranibizumab|DRUG: Placebo|OTHER: Sham intravitreal (IVT) injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lisdexamfetamine Dimesylate in Residual Symptoms and Cognitive Impairment in Major Depressive Disorder.
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: Lisdexamfetamine Dimesylate (Vyvanse)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ultra-high-caloric, Fatty Diet in ALS
Status: NOT_YET_RECRUITING
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DIETARY_SUPPLEMENT: Ultra-high-caloric fatty diet|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Finerenone vs. Spironolactone in Patients With Primary Aldosteronism
Status: NOT_YET_RECRUITING
Conditions: Primary Aldosteronism
Interventions: DRUG: Finerenone|DRUG: Spironolactone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Noninferiority Trial of Liquid Human Milk Fortifier (HMF) Hydrolyzed Protein Versus Liquid HMF With Supplemental Liquid Protein
Status: COMPLETED
Conditions: Human Milk|Premature Birth of Newborn
Interventions: DIETARY_SUPPLEMENT: Similac Human Milk Fortifier Hydrolyzed Protein Concentrated Liquid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Ziprasidone vs. Sertraline/Haloperidol in Psychotic Depression
Status: COMPLETED
Conditions: Affective Disorders
Interventions: DRUG: Ziprasidone|DRUG: Sertraline|DRUG: Haloperidol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Substudy 03A: A Study of Immune and Targeted Combination Therapies in Participants With First Line (1L) Renal Cell Carcinoma (MK-3475-03A)
Status: ACTIVE_NOT_RECRUITING
Conditions: Carcinoma, Renal Cell
Interventions: BIOLOGICAL: Pembrolizumab|BIOLOGICAL: Favezelimab/Pembrolizumab|DRUG: Belzutifan|DRUG: Lenvatinib|BIOLOGICAL: Pembrolizumab/Quavonlimab|DRUG: Vibostolimab/Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Effect of Food on Absorption of Megace ES
Status: COMPLETED
Conditions: Pharmacokinetics|Bioavailability|Absorption
Interventions: DRUG: Megestrol acetate oral suspension 625 mg/5 mL|DRUG: Megestrol acetate oral suspension 625 mg/5 mL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Multi-task Gait Training Mode to Enhance Walking Function in Patients With Chronic Stroke
Status: COMPLETED
Conditions: Stroke
Interventions: OTHER: The multi-task overground walking training|DEVICE: The multi-task treadmill walking training|OTHER: Traditional rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Transcranial Direct Current Stimulation (tDCS) on Neuropathic Symptoms Following Burn Injury
Status: COMPLETED
Conditions: Burn Injury|Chronic Pain|Pruritus|Itching
Interventions: DEVICE: Transcranial direct current stimulation (tDCS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Observational Study of Clinical Treatments for Patients With Oropharyngeal Carcinoma
Status: RECRUITING
Conditions: Oropharynx Carcinoma
Interventions: PROCEDURE: Surgery for early-stage OPC|RADIATION: RT for early-stage OPC|RADIATION: CRT for advanced OPC|OTHER: Surgery for advanced OPC|PROCEDURE: Neoadjuvant treatment for advanced OPC
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy of Intralesional Sodium Thiosulfate Versus Intralesional Saline for Dystrophic and Idiopathic Calcinosis Cutis
Status: TERMINATED
Conditions: Calcinosis Cutis
Interventions: DRUG: Sodium Thiosulfate|OTHER: Saline Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Food Hypersensitivity in Children/Adolescents With Functional Dyspepsia
Status: COMPLETED
Conditions: Dyspepsia
Interventions: DEVICE: in vitro and in vivo allergy testing
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Prospective Randomized Study to Evaluate the Effect of Embryonic Observation on the Gestation (PROdE)
Status: TERMINATED
Conditions: Placenta; Implantation
Interventions: OTHER: Embryo observation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: OTHER
Clinical trial: Study of Telbivudine and Lamivudine to Prevent Vertical Transmission of Hepatitis B
Status: COMPLETED
Conditions: Chronic Hepatitis B|Late Pregnancy|Transmission|Complication
Interventions: DRUG: Telbivudine|DRUG: Lamivudine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Improving Employment in Patients Who Have Survived Cervical Cancer, Uterine Cancer, or Ovarian Cancer
Status: COMPLETED
Conditions: Cervical Cancer|Ovarian Cancer|Sarcoma
Interventions: OTHER: counseling intervention|OTHER: study of socioeconomic and demographic variables
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: OTHER
Clinical trial: Retrospective Registry Providing Baseline Data on the Outcome of Left Atrial (LA) or LA Appendage (LAA) Thrombus in Patients With Nonvalvular Atrial Fibrillation (AF) or Atrial Flutter After Standard of Care (SoC) Anticoagulant Therapy
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: OTHER: no drug
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Mupirocin Ointment to Eliminate Nasal Carriage of Staphylococcus Aureus in HIV Infection
Status: COMPLETED
Conditions: Staphylococcus Aureus|HIV Infections
Interventions: DRUG: Mupirocin calcium ointment, 2%|DRUG: Placebo ointment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Adaptive Intervention for Depression Among Latinos Living With HIV
Status: COMPLETED
Conditions: Depression
Interventions: BEHAVIORAL: Augment w/mHealth|BEHAVIORAL: Maintenance|BEHAVIORAL: Switch to CBT & mHealth|BEHAVIORAL: Augment w/BAT & mHealth
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of a Daily Life Activity-Based Awareness Training Program on Hypertensive Individuals
Status: COMPLETED
Conditions: Hypertension|Cardiovascular Diseases|Self Efficacy|Treatment Adherence and Compliance|Health Behavior
Interventions: BEHAVIORAL: Hypertension Self Management Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Medical Food Formulation Pharmacokinetic (PK) Study in Medium Chain Triglycerides
Status: WITHDRAWN
Conditions: Alzheimer Disease
Interventions: OTHER: MCTprocal medical food|OTHER: Milk/tricaprilin oil blend|OTHER: AC-1207|OTHER: AC-1205|OTHER: AC-1206|DRUG: AC-1202
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study to Evaluate the Safety, Tolerability of HH-003 Injection in Participants With Chronic Hepatitis B Virus Infection
Status: COMPLETED
Conditions: Chronic HBV Infection
Interventions: DRUG: HH-003 injection|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating the Safety and Efficacy of Hormone Replacement Therapy With ST-1891 Compared to Levothyroxine in Patients With Primary Hypothyroidism
Status: COMPLETED
Conditions: Hypothyroidism
Interventions: DRUG: ST-1891|DRUG: Levothyroxine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Weekly Paclitaxel/Carboplatin/Bevacizumab as First Line Therapy for Triple Negative Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Carboplatin|DRUG: Bevacizumab|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity Study of 20vPnC in Healthy Children 15 Months Through 17 Years of Age
Status: COMPLETED
Conditions: Pneumococcal Disease
Interventions: BIOLOGICAL: 20vPnC
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy, Safety and Immunogenicity Study of Recombinant Zoster Vaccine(CHO Cell) in Adults Aged 40 Years and Older
Status: NOT_YET_RECRUITING
Conditions: Herpes Zoster
Interventions: BIOLOGICAL: Recombinant Zoster Vaccine (CHO Cell)|BIOLOGICAL: NaCl solution Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Office Based Vergence/Accommodative Therapy for the Treatment of Intermittent Exotropia
Status: UNKNOWN
Conditions: Intermittent Exotropia
Interventions: BEHAVIORAL: Office-based accommodative/vergence therapy and home reinforcement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison the Effects of Inspiratory Muscle Training and Aerobic Exercise Training in Patients With Post COVID-19
Status: RECRUITING
Conditions: COVID-19|Aerobic Exercise|Inspiratory Muscle Training|Physical Activity|Oxygen Consumption
Interventions: OTHER: Inspiratory Muscle Training Group|OTHER: High Intensity Interval Training Group|OTHER: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: DCB for Dialysis Access Stent Graft Restenosis
Status: UNKNOWN
Conditions: Hemodialysis Access Failure (Disorder)|Stent-Graft Restenosis|Arteriovenous Graft|Drug-coated Balloon
Interventions: DEVICE: Regular balloon|DEVICE: DCB (paclitaxel-coated balloon)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II 177Lu-DOTATATE Study in Metastatic NPC With a Safety Run-in
Status: RECRUITING
Conditions: Metastatic Nasopharyngeal Cancer
Interventions: RADIATION: 77 Lu-DOTA0-Tyr3-Octreotate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High Dose Preoperative Cholecalciferol Supplementation and Perioperative Vitamin D Status
Status: COMPLETED
Conditions: Hypovitaminosis D
Interventions: DRUG: 100,000 IU cholecalciferol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Zypan Functional Dyspepsia
Status: RECRUITING
Conditions: Dyspepsia
Interventions: DIETARY_SUPPLEMENT: Zypan|DIETARY_SUPPLEMENT: Placebo Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Modulation of THC Effects by CBD: a Dose-ranging Study
Status: NOT_YET_RECRUITING
Conditions: Cannabis|THC
Interventions: DRUG: ∆9-tetrahydrocannabinol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Phase III Study To Evaluate Alirocumab in Patients With Hypercholesterolemia Not Treated With a Statin (ODYSSEY CHOICE II)
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DRUG: Alirocumab|DRUG: Placebo (for Alirocumab)|DRUG: Non-statin LMT|OTHER: Diet Alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of a Novel BET Inhibitor FT-1101 in Patients With Relapsed or Refractory Hematologic Malignancies
Status: COMPLETED
Conditions: Acute Myeloid Leukemia|Acute Myelogenous Leukemia|Myelodysplastic Syndrome|Non-Hodgkin Lymphoma
Interventions: DRUG: FT-1101|DRUG: Azacitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of HAIC Combined With Lenvatinib and Envolizumab in Potentially Resectable Hepatocellular Carcinoma
Status: NOT_YET_RECRUITING
Conditions: Potentially Resectable Hepatocellular Carcinoma
Interventions: DRUG: FOLFOX-HAIC+Lenvatinib+Envolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Lanthanum Carbonate on FGF-23 in Subjects With Stage 3 CKD
Status: COMPLETED
Conditions: Chronic Kidney Disease
Interventions: DRUG: Lanthanum carbonate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT