pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Characterization of 24-hour Lung Function Profiles of Inhaled Tiotropium + Olodaterol Fixed Dose Combination in Patients Suffering From Chronic Obstructive Pulmonary Disease
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: tiotropium + olodaterol|DRUG: tiotropium|DRUG: olodaterol|DRUG: tiotropium|DRUG: tiotropium + olodaterol|DRUG: Placebo|DEVICE: Respimat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Cytoreductive Prostatectomy in Treating Patients With Newly Diagnosed, Metastatic Prostate Cancer
Status: COMPLETED
Conditions: Metastatic Prostate Carcinoma|Metastatic Prostatic Adenocarcinoma|Prostate Carcinoma Metastatic to the Bone
Interventions: PROCEDURE: Robotic Assisted Radical Prostatectomy|PROCEDURE: Conventional open retropubic radical prostectomy|OTHER: Laboratory Biomarker Analysis|OTHER: Quality-of-Life Assessment|DRUG: ADT (androgen deprivation therapy) (i.e. leuprolide) plus an androgen receptor inhibitor (i.e. bicalutamide)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Pharmacokinetics and Pharmacodynamics of Crystalline PX-866 Tablets and Amorphous PX-866 Capsules in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: PX-866
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anti-Shiga Toxin Hyperimmune Equine Immunoglobulin F(ab')2 Fragment (INM004) in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: BIOLOGICAL: Drug: INM004 Dose 1|BIOLOGICAL: Drug: INM004 Dose 2|BIOLOGICAL: Drug: INM004- Repeated dose|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: A Glutamate Transporter GLT1, in the Treatment of Bipolar Disorder
Status: WITHDRAWN
Conditions: Bipolar Disorder
Interventions: DRUG: Ceftriaxone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Inetetamab Combined With Pertuzumab and Paclitaxel/Carboplatin for Breast Cancer
Status: RECRUITING
Conditions: Locally Advanced Breast Cancer|Chemotherapy Effect
Interventions: DRUG: inetetamab with pertuzumab and paclitaxel/carboplatin (TCbIP) regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: LDLT in Non Resectable Colo-rectal Cancer Liver Metastasis
Status: RECRUITING
Conditions: Colon Adenocarcinoma|Liver Metastasis Colon Cancer
Interventions: PROCEDURE: Living donor liver transplant, Split liver transplant, RAPID, DDLT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Renal Denervation in End Stage Renal Disease Patients With Refractory Hypertension
Status: COMPLETED
Conditions: Kidney Failure, Chronic|Renal Dialysis
Interventions: DEVICE: Renal Denervation with a catheter-based procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Paracetamol-Tramadol and Paracetamol-caffeine Versus Placebo in the Emergency Discharge Treatment of Renal Colic
Status: RECRUITING
Conditions: Renal Colic
Interventions: DRUG: paracétamol tramadol|DRUG: Paracétamol cafeine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study to Enhance F18 FDG-PET Imaging of Prostate Cancers With the Metabolic Inhibitor Ranolazine
Status: COMPLETED
Conditions: Adenocarcinoma of the Prostate|Bone Metastases|Soft Tissue Metastases|Stage IIA Prostate Cancer|Stage IIB Prostate Cancer|Stage III Prostate Cancer|Stage IV Prostate Cancer
Interventions: DRUG: Ranolazine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Scaling up Trauma-Informed Outreach With People Affected by Violence - CLOE Intervention
Status: ENROLLING_BY_INVITATION
Conditions: Gender-based Violence|Outreach Intervention
Interventions: OTHER: CLOE Outreach Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Evaluate the Efficacy and Safety of ABT-126 in Subjects With Mild to Moderate Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: placebo|DRUG: donepezil|DRUG: ABT-126
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An Observational Study of Cholesterol in Coronary Arteries
Status: COMPLETED
Conditions: Myocardial Infarction|Angina|Coronary Artery Disease|Myocardial Ischemia
Interventions: DEVICE: Intravascular Near Infrared Spectroscopy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical Study to Evaluate the Efficacy of Two Dentifrices for Dentine Hypersensitivity
Status: COMPLETED
Conditions: Dentine Sensitivity
Interventions: DEVICE: Calcium sodium phosphosilicate|OTHER: Sodium fluoride|OTHER: Sodium monofluorophosphate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dual Mobility Cup: Does it Improve Patient's Satisfaction After Total Hip Arthroplastry?
Status: COMPLETED
Conditions: Patient Satisfaction|Hip Osteoarthritis
Interventions: PROCEDURE: large head|PROCEDURE: dual mobility cup
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Safety and Efficacy of OAS in Treating Severely Calcified Coronary Lesions
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DEVICE: Diamondback 360 Orbital Atherectomy System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Bilateral Sagittal Split Osteotomy Induced Paresthesia Using Ultrasonic vs. Reciprocating Saw Instrumentation
Status: COMPLETED
Conditions: Surgical Complication|Paresthesia|Fracture|Nerve Injury|Nerve Entrapments|Mandibular Nerve Injuries|Mandibular Hypoplasia|Mandibular Retrognathism|Mandibular Hyperplasia|Mandibular Prognathism
Interventions: DEVICE: Sonopet ultrasonic saw|DEVICE: Reciprocating saw
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Bioequivalence Study of Two Formulations of Tablets Ramipril 10 mg in Healthy Volunteers Under Fasting Conditions
Status: COMPLETED
Conditions: Bioequivalence
Interventions: DRUG: Ramipril tablet 10 mg|DRUG: Tritace® tablet 10 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Study to Evaluate the Efficacy and Safety of CJC-1134-PC in Patients With Type 2 Diabetes Mellitus Who Are Currently on Metformin Monotherapy
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: CJC-1134-PC|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CAVA: Dizziness Trial
Status: SUSPENDED
Conditions: Meniere's Disease|Benign Paroxysmal Positional Vertigo|Recurrent Vestibulopathy|Vestibular Migraine
Interventions: DEVICE: CAVA Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Omega-3 Polyunsaturated Fatty Acids and Non-Muscle Invasive Bladder Cancer
Status: UNKNOWN
Conditions: Non-Muscle Invasive Bladder Cancer
Interventions: DRUG: n-3PUFAs Treatment|DRUG: Placebo Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Phase 3 Boosting Study for the SARS-CoV-2 rS Vaccine
Status: COMPLETED
Conditions: Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)
Interventions: BIOLOGICAL: NVX-CoV2373|BIOLOGICAL: BBIBP-CorV vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Delivering a Diuretic Into the Liver Artery Followed by Plugging up the Artery to Starve Out Liver Cancer Cells
Status: ACTIVE_NOT_RECRUITING
Conditions: Unresectable Hepatocellular Carcinoma
Interventions: PROCEDURE: Hepatic artery embolization (HAE)|DRUG: Bumetanide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Noninvasive Cardiovascular Diagnosis of Patients With Fully Magnetically Levitated Blood Pumps
Status: RECRUITING
Conditions: End-stage Heart Failure|Cardiomyopathies|Mechanical Circulatory Support
Interventions: DIAGNOSTIC_TEST: Routinely performed echo, ECG and hemodynamic monitoring
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety Study of Photodynamic Therapy Using Photocyanine Injection in Treating Patients With Malignant Tumors
Status: UNKNOWN
Conditions: Skin Cancer|Esophageal Cancer
Interventions: PROCEDURE: Photodynamic therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adjuvant Treatment of Breast Cancer With 1-3 Aflicted Lymph Nodes
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Cyclophosphamide, Epirubicin, Paclitaxel|DRUG: Epirubicin, Paclitaxel, Filgrastim
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Pharmacokinetics, Safety, Tolerability of Repeated Dose Transdermal Rotigotine in Japanese and Caucasian Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Rotigotine transdermal patch 1mg / 24 hours|DRUG: Rotigotine transdermal patch 2 mg / 24 hours|DRUG: Rotigotine transdermal patch 4 mg / 24 hours
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Decrease of Neuropsychiatric Side Effects After Switching From Atripla to Eviplera
Status: TERMINATED
Conditions: HIV
Interventions: DRUG: Tenofovir disoproxil/emtricitabine/rilpivirine|DRUG: Tenofovir disoproxil/emtricitabine/efavirenz
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Incretin and KATP Channels
Status: TERMINATED
Conditions: Healthy Subjects
Interventions: OTHER: Intradermal injections of GLP-1 and its analogues
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Hybrid Approach to Mirror Therapy and Transcranial Direct Current Stimulation for Stroke Recovery
Status: COMPLETED
Conditions: Cerebrovascular Accident
Interventions: BEHAVIORAL: Mirror Therapy with tDCS|BEHAVIORAL: Mirror Therapy with sham-tDCS|BEHAVIORAL: Mirror Therapy|BEHAVIORAL: Control Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vaccine Therapy for Multiple Myeloma Utilizing Idiotype-Pulsed Allogeneic Dendritic Cells
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: BIOLOGICAL: Idiotype-pulsed allogeneic dendritic cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Dietary Soy on Estrogens in Breast Fluid, Blood, and Urine Samples From Healthy Women
Status: COMPLETED
Conditions: Breast Cancer|Healthy, no Evidence of Disease
Interventions: DIETARY_SUPPLEMENT: soy isoflavones
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: PREVENTION
Clinical trial: Integrated Metacognitive Therapy in First Episode Psychosis
Status: COMPLETED
Conditions: Schizophrenia|Schizophreniform Disorder|Schizoaffective Disorder
Interventions: BEHAVIORAL: Integrated Metacognitive Therapy|BEHAVIORAL: Treatment as Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Biphasic Material With PRF in Lateral Sinus Floor Augmentation
Status: NOT_YET_RECRUITING
Conditions: Maxillary Sinus Disease
Interventions: PROCEDURE: Lateral sinus floor augmentation|DRUG: Biphasic Calcium Phosphate|PROCEDURE: Injectable platlets rich fibrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: S1406 Phase II Study of Irinotecan and Cetuximab With or Without Vemurafenib in BRAF Mutant Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: BIOLOGICAL: cetuximab|DRUG: irinotecan hydrochloride|DRUG: vemurafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Complex Motor Learning With Motor Imaginary
Status: UNKNOWN
Conditions: Learning Disturbance
Interventions: OTHER: Motor imaginary|OTHER: Non Motor imaginary|OTHER: tDCS|OTHER: tDCS sham|OTHER: Neurofeedback|OTHER: Neurofeedback sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Safety and Efficacy Study to Evaluate Romosozumab (AMG 785) in South Korean Women With Osteoporosis
Status: COMPLETED
Conditions: Postmenopausal Osteoporosis
Interventions: DRUG: Romosozumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pacing in Left Ventricular Assist Device Recipients
Status: UNKNOWN
Conditions: Heart Rate|Chronotropic Incompetence|Pacing
Interventions: OTHER: Peak oxygen uptake test with pacing|OTHER: Peak oxygen uptake test without pacing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study to Assess Efficacy of Besifovir and L-carnitine in Chronic Hepatitis B Patients With Nonalcoholic Fatty Liver
Status: UNKNOWN
Conditions: Hepatitis B
Interventions: DRUG: Besifovir dipivoxil|DRUG: L-carnitine|DRUG: Tenofovir Alafenamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Effect of Two Educational Videos for People With Knee Osteoarthritis (vidEO)
Status: COMPLETED
Conditions: Knee Osteoarthritis|Patient Empowerment
Interventions: OTHER: Patient education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Multi-level Approach to Violence Prevention Among African American Adolescents
Status: COMPLETED
Conditions: Violence in Adolescence
Interventions: BEHAVIORAL: Multi-level Violence Prevention Intervention - Boys|BEHAVIORAL: Multi-level Violence Prevention Intervention - Caregivers
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effects of Vibrotactile Stimulation in Patients With Movement Disorders
Status: COMPLETED
Conditions: Parkinson Disease|Essential Tremor|Dystonia
Interventions: OTHER: skin surface vibration|OTHER: light skin surface vibration- SHAM
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MB-CART19.1 r/r CD19+ B-cell Malignancies (BCM)
Status: RECRUITING
Conditions: Acute Lymphoblastic Leukemia Recurrent|B-cell Lymphoma Recurrent|B-cell Lymphoma Refractory|Chronic Lymphocytic Leukemia Recurrent|Chronic Lymphocytic Leukemia Refractory
Interventions: BIOLOGICAL: MB-CART19.1
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Xience or Vision Stent Management of Angina in the Elderly
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: PROCEDURE: Percutaneous Coronary Intervention using drug eluting stents|PROCEDURE: Percutaneous Coronary Intervention using bare metal stents
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EMG Modules as a Novel Biomarker of Basal Ganglia Plasticity in Parkinson's Disease
Status: TERMINATED
Conditions: Parkinson
Interventions: OTHER: Surface EMG, MRI and PET Scan|OTHER: Surface EMG
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Pain and Discomfort in Two Acceleration Methods of Canine Retraction
Status: COMPLETED
Conditions: Class II Malocclusion
Interventions: PROCEDURE: Piezosurgery|OTHER: Low-level laser therapy|DEVICE: Traditional treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Exploratory Pharmacogenomic Study of Monotherapy Erbitux in Subjects With Metastatic Non Small Cell Lung Carcinoma
Status: COMPLETED
Conditions: Carcinoma, Non-Small-Cell Lung|Neoplasm Metastasis
Interventions: DRUG: Cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Comparison of the Clinical Efficacy Between I-gel and LMA-Supreme, the Two Most Recently Developed Supraglottic Airway Devices, in Infants
Status: UNKNOWN
Conditions: Elective Surgery of Short Duration (Less Than 2 hr) Undergoing General Anesthesia Using Supraglottic Airway
Interventions: DEVICE: I gel|DEVICE: LMA Supreme
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: Morning-Only 4 L PEG vs Split Dose Prep for Afternoon Colonoscopies, Endoscopist-Blinded Prospective Study
Status: COMPLETED
Conditions: Colonoscopy
Interventions: DRUG: Same day 4 L preparation (Polyethylene Glycol)|DRUG: Split dose 4 L preparation (Polyethylene Glycol)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Alemtuzumab on Surrogate Markers of Disease Activity and Repair Using Advanced MRI Measures in Subjects With Relapsing Remitting Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DRUG: Alemtuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Closed-loop Control of Glucose Levels (Artificial Pancreas) for 5 Days in Adults With Type 1 Diabetes
Status: WITHDRAWN
Conditions: Type 1 Diabetes
Interventions: OTHER: 5-day intervention with single-hormone closed-loop strategy|OTHER: 5-day intervention with sensor-augmented pump therapy|DEVICE: Insulin pump|DEVICE: Continuous glucose monitoring system|DRUG: Insulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of OnabotulinumtoxinA for the Treatment of Urinary Incontinence Due to Neurogenic Detrusor Overactivity (NDO) in Non-Catheterizing Patients With Multiple Sclerosis (MS)
Status: COMPLETED
Conditions: Urinary Incontinence|Multiple Sclerosis|Neurogenic Bladder
Interventions: BIOLOGICAL: OnabotulinumtoxinA|DRUG: Placebo (Normal Saline)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Open-Label Study of Atomoxetine in Children With Attention-Deficit/Hyperactivity Disorder
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: DRUG: Atomoxetine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Decitabine for Myelodysplastic Syndromes and Acute Myeloid Leukemia Before Allogeneic Hematopoietic Cell Transplantation
Status: UNKNOWN
Conditions: Higher-risk Myelodysplastic Syndrome|Relapsed /Refractory Acute Myeloid Leukemia
Interventions: DRUG: decitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of the Serratus Block on Pain Control After Breast Surgery
Status: COMPLETED
Conditions: Anesthesia
Interventions: PROCEDURE: Serratus Block|PROCEDURE: Placebo Block|DRUG: ropivacaine|DRUG: epinephrine|OTHER: sterile saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Exploration of Feasability of Blood and Saliva Proteomic Analysis Through Harvesting by Silica Matrix (NanoDx-CoV-19)
Status: UNKNOWN
Conditions: Covid19
Interventions: DEVICE: sample of blood and saliva
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Immunomodulation by OM-85 (Broncho-Vaxom) in Early AD
Status: TERMINATED
Conditions: Atopic Dermatitis
Interventions: DRUG: Broncho-Vaxom|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Local Anesthetic Dose in PENG Block Performed in Total Hip Replacement Operations
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: DRUG: Bupivacaine HCl 0.5 % in 20 ML Injection|DRUG: Bupivacaine HCl 0.25 % in 20 ML Injection|DRUG: Bupivacaine HCl 0.125 % in 20 ML Injection|DRUG: NaCl 0.9%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Prognostic Value of Soluble Urokinase Plasminogen Activation Receptor (SUPAR) to Rule Out Complications in Patients Admitted in Emergency Department for Acute Abdominal Pain.
Status: COMPLETED
Conditions: Soluble Urokinase Plasminogen Activation Receptor|Abdominal Pain|Emergency Department|Mortality
Interventions: DIAGNOSTIC_TEST: Soluble Urokinase Plasminogen Activation Receptor measurement
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Studying How Outpatient Water affEcts Risks With Drains (SHOWER Study)
Status: RECRUITING
Conditions: Postoperative Wound Infection|Postoperative Complications|Surgical Site Infection|Drain Site Complication
Interventions: OTHER: Showering|OTHER: Restriction of Showering
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy And Safety Of MK-6194 In Adult Participants With Systemic Lupus Erythematosus (MK-6194-006)
Status: RECRUITING
Conditions: Systemic Lupus Erythematosus
Interventions: BIOLOGICAL: MK-6194|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: BUCY+VP-16 vs BUCY Conditioning Regimen for DLBCL Undergoing Auto-HSCT
Status: UNKNOWN
Conditions: Autologous Hematopoietic Stem Cell Transplantation|Diffuse Large B-cell Lymphoma|Conditioning
Interventions: DRUG: Busulfan (BU)|DRUG: Cyclophosphamide (CY)|DRUG: Etoposide (VP-16)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Virtual Reality Therapy for Cancer-Treatment Associated Symptoms
Status: NOT_YET_RECRUITING
Conditions: Cancer|Cancer Pain|Virtual Reality
Interventions: DEVICE: Relievrx|OTHER: Audio Mp4
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multi-modal Assessment of Gamma-aminobutyric Acid (GABA) Function in Psychosis
Status: RECRUITING
Conditions: Schizophrenia|Bipolar Disorder|Healthy|Psychosis|Schizophreniform Disorders|Schizo Affective Disorder|Major Depression With Psychotic Features
Interventions: OTHER: Placebo and fMRI|DRUG: Lorazepam and fMRI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Aspirin on Uterine Endometrial Repair Severe Intrauterine Adhesion
Status: COMPLETED
Conditions: Intrauterine Adhesion
Interventions: DRUG: Aspirin|DEVICE: intrauterine balloon
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efalizumab in Treating Patients With Graft-Versus-Host Disease of the Skin That Did Not Respond to Previous Steroids
Status: TERMINATED
Conditions: Graft Versus Host Disease
Interventions: BIOLOGICAL: efalizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Reaching Protein Target With SmofKabiven® Extra Nitrogen vs Olimel N9E During the Early Phase of Acute Critical Illness
Status: TERMINATED
Conditions: Critical Illness
Interventions: DRUG: SmofKabiven® extra Nitrogen|DRUG: Olimel N9E
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Preliminary Efficacy and Safety Study of ST101 Plus Aricept in Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: ST101|DRUG: ST101|DRUG: ST101|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Weekly Idrabiotaparinux Sodium Versus Oral Adjusted-dose Warfarin to Prevent Stroke and Systemic Thromboembolic Events in Patients With Atrial Fibrillation
Status: TERMINATED
Conditions: Atrial Fibrillation
Interventions: DRUG: Idrabiotaparinux sodium|DRUG: Warfarin|DRUG: Placebo (for idrabiotaparinux)|DRUG: Placebo (for warfarin)|DRUG: Avidin|DRUG: Placebo (for avidin)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Perfusion MRI in Reversible Cerebral Vasoconstriction Syndrome
Status: UNKNOWN
Conditions: Reversible Cerebral Vasoconstriction Syndrome
Interventions: DEVICE: MRI brain|DEVICE: ASL-MRI brain|DEVICE: MRA brain
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study Of SU011248 As Therapy In Patients With Locally Advanced Or Metastatic Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: carboplatin|DRUG: paclitaxel|DRUG: sunitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Dry Needling and Strain Counter Strain Technique in Myofascial Trigger Points of Upper Trapezius
Status: COMPLETED
Conditions: Trigger Point Pain, Myofascial
Interventions: OTHER: Dry Needling|OTHER: Strain counter strain
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of Zoledronic Acid in Combination With First-line Chemotherapy in Aged Patients With Lung Cancer
Status: UNKNOWN
Conditions: Lung Cancer
Interventions: DRUG: Zoledronic acid plus EP/TP|DRUG: EP/TP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Physical Activity Promotion in Children and Adolescents With Single Ventricle Physiology (MedBike)
Status: COMPLETED
Conditions: Congenital Heart Defect|Hypoplastic Left Heart Syndrome|Physical Activity
Interventions: DEVICE: MedBIKE
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Assessing the Dose Response of a Lead Fiber Snack Prototype
Status: COMPLETED
Conditions: Microbiota|Gastrointestinal Microbiome
Interventions: OTHER: Controlled, high fat/low fiber diet background diet, sequentially supplemented with an escalating dose of a fiber-blend snack food.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Combined Effects of GLP-1 Analogue and Exercise on Maintenance of Weight Loss and Health After Very-low Calorie Diet
Status: UNKNOWN
Conditions: Obesity
Interventions: DRUG: Liraglutide|BEHAVIORAL: Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Photobiomodulation for Plantar Fasciitis
Status: COMPLETED
Conditions: Plantar Fascitis
Interventions: OTHER: Stretching|OTHER: Cryotherapy|DEVICE: Photobiomodulation Low Power|DEVICE: Photobiomodulation High Power
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Bioequivalence Study of Domestic (Made in China) and Imported Mizolastine Tablets in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Mizolastine domestic (made in China)|DRUG: Mizolastine (imported)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: COHERE - COntextualized Care in cHcs' Electronic Health REcords
Status: ACTIVE_NOT_RECRUITING
Conditions: Hypertension|Diabetes Mellitus, Type 2
Interventions: OTHER: CDS Tool Access
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Japan Alteplase Clinical Trial (J-ACT): Efficacy and Safety Study of Tissue Plasminogen Activator (Alteplase) for Ischemic Stroke
Status: COMPLETED
Conditions: Cerebral Infarction|Brain Ischemia
Interventions: DRUG: Alteplase
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Novel Combination of Belantamab Mafodotin and Elotuzumab to Enhance Therapeutic Efficacy in Multiple Myeloma
Status: RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: Elotuzumab|DRUG: Belantamab mafodotin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Immediate Treatment of CIN1 With Cryotherapy and 12 Month Cytology Follow up in HIV Seropositive Women
Status: UNKNOWN
Conditions: Cervical Dysplasia
Interventions: PROCEDURE: cryotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acalabrutinib Plus RICE for Relapsed/Refractory DLBCL
Status: UNKNOWN
Conditions: Diffuse Large B Cell Lymphoma
Interventions: DRUG: Carboplatin|DRUG: Ifosfamide|DRUG: Etoposide|BIOLOGICAL: Rituximab|DRUG: Carmustine|DRUG: Cytarabine|DRUG: Melphalan|OTHER: Autologous HSCT|DRUG: Acalabrutinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Inhaled Budesonide and Acute Mountain Sickness
Status: COMPLETED
Conditions: Acute Mountain Sickness
Interventions: DRUG: Budesonide 200|DRUG: Budesonide 800|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Neoadjuvant mFOLFIRINOX With Perioperative Oral Hydroxychloroquine in Resectable Pancreatic Adenocarcinoma
Status: RECRUITING
Conditions: Adenocarcinoma of the Pancreas
Interventions: DRUG: Hydroxychloroquine sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Baclofen Effects on Marijuana Dependence
Status: COMPLETED
Conditions: Marijuana Dependence
Interventions: DRUG: Baclofen|BEHAVIORAL: Psychosocial|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Tai Chi Chuan in Patients After Recent Acute Myocardial Infarction
Status: COMPLETED
Conditions: Acute Myocardial Infarction
Interventions: OTHER: Tai Chi Chuan exercise|OTHER: stretching exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Effect of Megestrol Acetate in Weight Loss in Dementia Patients
Status: TERMINATED
Conditions: Dementia
Interventions: DRUG: Megestrol acetate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Surgery Outcome Between Preoperative IVR and Intraoperative IVR in PPV for PDR
Status: COMPLETED
Conditions: Proliferative Diabetic Retinopathy
Interventions: PROCEDURE: preoperative group and intraoperative group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of ARC-520 at Varying Infusion Rates in Healthy Adult Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: ARC-520|DRUG: cetirizine|DRUG: diphenhydramine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of White Spot Lesions Treated by S-PRG and ICON
Status: UNKNOWN
Conditions: White Spot Lesion
Interventions: OTHER: Giomer|OTHER: Two composite resin sealants
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Neoantigen Vaccine Plus Capecitabine as Adjuvant Therapy for Intrahepatic Cholangiocarcinoma After Radical Resection
Status: NOT_YET_RECRUITING
Conditions: Intrahepatic Cholangiocarcinoma
Interventions: COMBINATION_PRODUCT: Neoantigen Vaccine plus Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Awake Tracheal Intubation in Critical Care Patients
Status: COMPLETED
Conditions: Videolaryngoscopy|Intensive Care Unit Syndrome
Interventions: DEVICE: tracheal intubation using videolaryngoscope with a hyperangulated blade or standard intubation videolaryngoscopy (VL) and direct laryngoscopy (DL)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Intravenous BI 836826 in Combination With Ibrutinib in Relapsed/Refractory CLL Patients Who Have Been Pre-treated With at Least One Prior Line of Systemic Therapy, and Who Are Eligible for Treatment With Ibrutinib
Status: COMPLETED
Conditions: Leukemia, Lymphocytic, Chronic, B-Cell
Interventions: DRUG: BI 836826|DRUG: Ibrutinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Nebulized Lidocaine on Postoperative Sore Throat
Status: TERMINATED
Conditions: Sore Throat
Interventions: OTHER: Saline|OTHER: Lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: An Investigation Of The Absorption And Pharmacokinetics Of Multiple Doses Of A Controlled Release Pregabalin Tablet As Compared To Multiple Doses Of The Immediate Release Pregabalin Capsule In Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Pregabalin immediate release, 300 mg|DRUG: Pregabalin controlled release, 330 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: mXELOXIRI Combined With Molecular Targeted Drug in mCRC
Status: UNKNOWN
Conditions: Unresectable Metastatic Colorectal Cancer
Interventions: DRUG: Capecitabine-Oxaliplatin-Irinotecan Combination
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of an Updated Version of the Program "BlinkBlink" for Alleviation of Dry Eye Symptoms Induced by Computer Work
Status: COMPLETED
Conditions: Dry Eye Syndromes|Computer Vision Syndrome
Interventions: DEVICE: Animation program "BlinkBlink"
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Dose Ranging Vehicle Controlled Study to Determine the Safety and Efficacy of Permethrin Foam, 5% and Permethrin Foam, 4% for the Treatment of Scabies
Status: COMPLETED
Conditions: Scabies
Interventions: DRUG: Permethrin Foam 4%|DRUG: Permethrin Foam 5%|DRUG: Vehicle Foam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Reduction in Pain Intensity Following IV or Oral Pain-relieving Products
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: IV Acetaminophen (Treatment A)|DRUG: Oral Acetaminophen (Treatment B)|DRUG: Placebo (Treatment C)|OTHER: Morphine (Treatment D)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Acute Effects of Exercise in College Students With ADHD
Status: RECRUITING
Conditions: Attention Deficit Hyperactivity Disorder|Effects of; Exertion|Working Memory|Change in Sustained Attention
Interventions: BEHAVIORAL: Sprint Interval Training
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical, Pharmacological and Molecular Effects of IV and Oral Acetaminophen in Adults With aSAH
Status: TERMINATED
Conditions: Subarachnoid Hemorrhage|Stroke
Interventions: DRUG: IV acetaminophen|DRUG: Oral acetaminophen|DRUG: Oral placebo|DRUG: IV placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of EYP001a to Assess Its Safety and Anti-viral Effect in CHB Patients in Combination With NA (ETV or TD)
Status: TERMINATED
Conditions: Hepatitis B, Chronic
Interventions: DRUG: EYP001a|DRUG: Placebo|DRUG: Nucleotide analogue (Entecavir or Tenofovir Disoproxil)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Time and Virtual Reality in Schizophrenia and Bipolar Disorder
Status: UNKNOWN
Conditions: Schizophrenia|Bipolar Disorder
Interventions: BEHAVIORAL: virtual reality 1|BEHAVIORAL: virtual reality 2
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Composition for Treating Uterine Fibroid (PP6)
Status: COMPLETED
Conditions: Uterine Fibroids Affecting Pregnancy
Interventions: DRUG: PP6|DEVICE: PP6 Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Conventional Versus Patient-specific Instruments in Total Knee Arthroplasty
Status: UNKNOWN
Conditions: Osteoarthritis, Patient-specific Instruments
Interventions: PROCEDURE: patient-specific instruments|DEVICE: The Signature™ Vanguard|PROCEDURE: conventional instruments|DEVICE: Vanguard PS(posterior stabilized)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intraoperative Identification and Stimulation of the Glossopharyngeal Nerve
Status: ENROLLING_BY_INVITATION
Conditions: Head and Neck Cancer|Obstructive Sleep Apnea
Interventions: DEVICE: Nerve stimulation using nerve stimulation device and sterile wire electrode.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of a Comfort Scale and a Numerical Pain Scale on Opioid Consumption After Surgery
Status: COMPLETED
Conditions: Pain Management|Analgesia
Interventions: OTHER: Informed consent|PROCEDURE: Surgery|BEHAVIORAL: Comfort scale|BEHAVIORAL: Pain|OTHER: Questionnaires
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Surgical Offloading Procedures for Diabetic Foot Ulcers
Status: UNKNOWN
Conditions: Diabetic Foot Ulcer
Interventions: PROCEDURE: Group 1 early offloading surgery|PROCEDURE: Group 2 - off-loading in fiberglass cast
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Horizontal Maxillary Ridge Augmentation With Sticky Bone Versus Collagen Membrane GBR
Status: UNKNOWN
Conditions: Horizontal Deficiecy in Maxillary Arches
Interventions: DEVICE: Ridge augmentation with sticky bone and GBR
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I Trial to Evaluate the Safety, Tolerability and Immunogenicity of VGX-6150 for Second-line Therapy of Chronic Hepatitis C Infection
Status: COMPLETED
Conditions: Hepatitis C, Chronic
Interventions: BIOLOGICAL: VGX-6150
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study To Assess The Safety, Tolerability And Pharmacokinetics Of Metronidazole Injection In Healthy Japanese Subjects
Status: COMPLETED
Conditions: Infection
Interventions: DRUG: metronidazole IV 500 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Consumption of Cowpea Leaves on Postprandial Blood Glucose in Black Adults, a Pilot Study
Status: COMPLETED
Conditions: Black Ethnicity
Interventions: OTHER: Cowpea leaves mixed with Jam|OTHER: Jam mixed with green food colour
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Different Types of Milk in Improving Sleep Quality in Subjects With Sleep Problems (Milca)
Status: COMPLETED
Conditions: Poor Quality Sleep
Interventions: DIETARY_SUPPLEMENT: Control Product|DIETARY_SUPPLEMENT: Experimental Product: 250|DIETARY_SUPPLEMENT: Experimental Product: 250 + TRP|DIETARY_SUPPLEMENT: Experimental Product: 600
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: The Effects of Sedentarism on Vascular Function, Inflammation, and Insulin Resistance
Status: TERMINATED
Conditions: Endothelial Dysfunction|Insulin Resistance|Metabolic Syndrome|Peripheral Arterial Disease
Interventions: DIETARY_SUPPLEMENT: Fish Oil (Omega-3 Fatty Acids)|DIETARY_SUPPLEMENT: Fish Oil (Omega-3 Fatty Acids)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of TAK-875 Compared to Glimepiride When Used With Metformin in Participants With Type 2 Diabetes
Status: TERMINATED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: TAK-875|DRUG: TAK-875|DRUG: Glimepiride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Displacement of Popliteal Sciatic Nerve Catheters After Major Foot and Ankle Surgery
Status: COMPLETED
Conditions: Postoperative Pain|Regional Anesthesia
Interventions: PROCEDURE: Ultrasound guided short axis (SAX) placement of sciatic nerve catheters|PROCEDURE: Ultrasound guided long axis (LAX) placement of sciatic nerve catheters|DEVICE: B Braun Contiplex S catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC