pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Clinical Study to Evaluate the Safety, Tolerability and Pharmacokinetics and Pharmacodynamics of ZYIL1 Following Oral Administration in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: ZYIL1 Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Needle-Free Subcutaneous Injector and Conventional Intramuscular Injection of Mecobalamin in Diabetes Peripheral Neuropathy
Status: NOT_YET_RECRUITING
Conditions: Diabetic Peripheral Neuropathy
Interventions: OTHER: needle-free subcutaneous injector for Mecbl|OTHER: intramuscular injection of Mecbl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Safety and Immunogenicity of a SARS-CoV-2 rS Nanoparticle Vaccine With/Without Matrix-M Adjuvant
Status: COMPLETED
Conditions: COVID-19
Interventions: BIOLOGICAL: SARS-CoV-2 rS - Phase 1|BIOLOGICAL: SARS-CoV-2 rS/Matrix-M Adjuvant - Phase 1|OTHER: Normal saline solution (NSS), Placebo - Phase 1|OTHER: Normal saline solution (NSS), Placebo - Phase 2|BIOLOGICAL: SARS-CoV-2 rS/Matrix-M Adjuvant, Day 0 - Phase 1|OTHER: Normal saline solution (NSS), Placebo, Day 21 - Phase 1|BIOLOGICAL: SARS-CoV-2 rS/Matrix-M Adjuvant - Phase 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Trial of Combination ABI-007, Carboplatin, and Gemcitabine for First Line Treatment of Advanced Urothelial Cancer
Status: TERMINATED
Conditions: Urothelial Cancer|Bladder Cancer
Interventions: DRUG: ABI-007 (Abraxane®)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HD IL-2 + Vemurafenib in Patients With BRAF Mutation Positive Metastatic Melanoma
Status: TERMINATED
Conditions: Metastatic Melanoma
Interventions: DRUG: vemurafenib + HD IL-2
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Anti-VEGF Gene Therapy Trial for Vestibular Schwannoma
Status: RECRUITING
Conditions: Vestibular Schwannoma
Interventions: COMBINATION_PRODUCT: AAVAnc80-antiVEGF via Akouos Delivery Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Bioequivalence Study of Sacubitril/Valsartan Film-coated Tablets Under Fasting Conditions
Status: NOT_YET_RECRUITING
Conditions: Chronic Heart Failure
Interventions: DRUG: Sacubitril and Valsartan Tablets 97mg/103mg|DRUG: Entresto (Sacubitril and Valsartan Tablets 97mg/103mg)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Atropine vs Isoprenaline in the Invasive Diagnosis of Arrhythmias
Status: NOT_YET_RECRUITING
Conditions: Cardiac Arrhythmia|Supraventricular Arrhythmia
Interventions: DRUG: Comparison of atropine and isoprenaline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Special Use-Result Surveillance of Unasyn-S (Kit) for Intravenous Use - A Surveillance on High-dose (>6 g Daily) Administration -
Status: COMPLETED
Conditions: Pneumonia|Lung Abscess|Peritonitis
Interventions: DRUG: Sulbactam Sodium/Ampicillin Sodium
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phase 1 Study of the Litx™ BPH System in Patients With Lower Urinary Tract Symptoms (LUTS) Due to Benign Prostatic Hyperplasia (BPH)
Status: COMPLETED
Conditions: Benign Prostatic Hyperplasia|Lower Urinary Tract Symptoms
Interventions: DRUG: Talaporfin sodium|PROCEDURE: Placement of device in prostate urethra|DEVICE: Transurethral illumination with light emitting diodes (Litx™ BPH Device)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Changes in Muscle Morphology Resulting From Anterior Cruciate Ligament Reconstruction
Status: COMPLETED
Conditions: Isolated Anterior Cruciate Ligament Rupture
Interventions: OTHER: Autograft STG harvest from ACL-deficient leg|OTHER: Autograft harvest contralateral to ACL-deficient leg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Oral (Z)-Endoxifen in Premenopausal Women With Measurable Breast Density
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Density
Interventions: DRUG: Z-Endoxifen|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Chlorhexidine on the Oral and Lung Microbiota in Chronic Obstructive Pulmonary Disease
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Chlorhexidine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety and Tolerability of BI 638683 After Single Rising Oral Doses in Healthy Male Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BI 638683 or placebo|DRUG: Placebo solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Nasogastric Decompression Following Pancreaticoduodenectomy
Status: COMPLETED
Conditions: Pancreatic Head Neoplasm|Delayed Gastric Emptying|Post Operative Ileus|Whipple Procedure
Interventions: PROCEDURE: pancreaticoduodenectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long-term Safety and Efficacy Follow-up Study of PNEUMOSTEM® in Patients Who Completed PNEUMOSTEM® Phase-I Study
Status: COMPLETED
Conditions: Bronchopulmonary Dysplasia|Respiratory Tract Infections|Premature Birth of Newborn
Interventions: BIOLOGICAL: PNEUMOSTEM
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: the Clinical Performance of the Oxysoft Daily Disposable Silicone Hydrogel Soft Contact Lens
Status: COMPLETED
Conditions: Myopia
Interventions: DEVICE: oxysoft (olifilcon C)|DEVICE: Si-Hy (olifilcon B)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Infiltrations With Collagen in Episiotomy and Cesarean Scars
Status: COMPLETED
Conditions: Pelvic Pain
Interventions: COMBINATION_PRODUCT: Collagen|PROCEDURE: Rehabilitation sessions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Prospective Study of the Impact of Hippocampal Avoidance During Whole Brain Radiotherapy on Neurocognitive Function Decline
Status: RECRUITING
Conditions: Brain Metastasis|Brain Metastases
Interventions: RADIATION: hippocampal-sparing WBRT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Neoadjuvant FOLFIRINOX and FDR-Gemcitabine With Concurrent IMRT in Patients
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DRUG: FOLFIRINOX|RADIATION: Intensity-modulated radiotherapy (IMRT)|PROCEDURE: Surgical Exploration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of SHR-8068 Combined With Adebrelimab and Bevacizumab in the Treatment of Advanced Hepatocellular Carcinoma
Status: RECRUITING
Conditions: Advanced Hepatocellular Carcinoma
Interventions: DRUG: Adebrelimab|DRUG: Bevacizumab|DRUG: SHR-8068
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The GORE® VIAFORT Vascular Stent Iliofemoral Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Venous Thromboses|Venous Disease|Venous Leg Ulcer|Venous Stasis|Venous Ulcer|Venous Stenosis|Venous Occlusion|Vein Thrombosis|Vein Occlusion|Vein Disease
Interventions: DEVICE: GORE® VIAFORT Vascular Stent
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Randomised Trial of Cyclophosphamide and Dexamethasone in Combination With Ixazomib in Relapsed or Refractory Multiple Myeloma.
Status: UNKNOWN
Conditions: Multiple Myeloma
Interventions: DRUG: Ixazomib|DRUG: Cyclophosphamide|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare the Bioequivalence and Safety of JHL1101 and Rituximab in CD20 Positive B Cell Lymphoma Patients
Status: TERMINATED
Conditions: B Cell Lymphoma
Interventions: BIOLOGICAL: JHL1101|BIOLOGICAL: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Holmium-166-radioembolization in NET After Lutetium-177-dotatate; an Efficacy Study
Status: COMPLETED
Conditions: Neuroendocrine Tumors
Interventions: DEVICE: Holmium-166 microspheres hepatic radioembolization.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Supported Treadmill Ambulation Training (STAT) for Patients Diagnosed With Amyotrophic Lateral Aclerosis
Status: COMPLETED
Conditions: Amyotrophic Lateral Sclerosis|Motor Neuron Disease|Lou Gehrig's Disease
Interventions: BEHAVIORAL: Treadmill Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of the Glutaminase Inhibitor CB-839 in Hematological Tumors
Status: COMPLETED
Conditions: Non-Hodgkin's Lymphoma (NHL)|Multiple Myeloma|Waldenstrom's Macroglobulinemia (WM)|Other B-cell NHL Subtypes, Including WM|T-cell NHL
Interventions: DRUG: CB-839|DRUG: CB-839 and low dose dexamethasone|DRUG: CB-839, pomalidomide, and low dose dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Metabolic Efficiency With Ranolazine for Less Ischemia in Non-ST Elevation Acute Coronary Syndromes
Status: COMPLETED
Conditions: Myocardial Ischemia
Interventions: DRUG: Ranolazine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lumbar Erector Spinae Plane Block: Cadaveric Study
Status: COMPLETED
Conditions: Pain|Regional Anesthesia Morbidity|Arthroplasty Complications
Interventions: PROCEDURE: Lumbar erector spinae plane block
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Lipid Research Clinics Coronary Primary Prevention Trial (CPPT)
Status: COMPLETED
Conditions: Cardiovascular Diseases|Coronary Disease|Heart Diseases|Myocardial Ischemia
Interventions: DRUG: cholestyramine|BEHAVIORAL: diet, fat-restricted
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: A Study to Assess the Safety and Immunogenicity of the Malaria Vaccine, R21, Administered With and Without Matrix-M1
Status: COMPLETED
Conditions: Malaria
Interventions: BIOLOGICAL: R21|BIOLOGICAL: Matrix-M1
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Levocetirizine and Cetirizine in Reducing Symptoms of Seasonal Allergic Rhinitis in Ragweed Sensitive Subjects
Status: COMPLETED
Conditions: Rhinitis, Allergic, Seasonal
Interventions: DRUG: levocetirizine dihydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Interleukin-12 in Treating Patients With AIDS-Related Kaposi's Sarcoma
Status: COMPLETED
Conditions: Epidemic Kaposi's Sarcoma|Recurrent Kaposi's Sarcoma
Interventions: DRUG: interleukin-12
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Docetaxel With or Without Phenoxodiol in Treating Patients With Recurrent Advanced Ovarian Epithelial Cancer, Fallopian Tube Cancer, or Primary Peritoneal Cavity Cancer
Status: TERMINATED
Conditions: Fallopian Tube Cancer|Ovarian Cancer|Primary Peritoneal Cavity Cancer
Interventions: DRUG: docetaxel|DRUG: idronoxil|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess Sorafenib Alone and in Combination With Low-Dose Interferon Following Unsuccessful Treatment With Sunitinib in Patients With Advanced Renal Cell Cancer.
Status: TERMINATED
Conditions: Carcinoma, Renal Cell
Interventions: DRUG: Sorafenib (Nexavar, BAY43-9006)|DRUG: Sorafenib (Nexavar, BAY43-9006) + Interferon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Articaine and Bupivacaine in Impacted Tooth Surgery
Status: COMPLETED
Conditions: Impacted Third Molar Tooth
Interventions: PROCEDURE: Impacted tooth surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Ranibizumab and the Risk of Arterial Thromboembolic Events
Status: TERMINATED
Conditions: Age-related Macular Degeneration|Coronary Artery Disease|Cerebrovascular Disorders
Interventions: DRUG: 0.5 mg of ranibizumab|PROCEDURE: 0.5 mg of ranibizumab + photodynamic therapy|OTHER: Sham injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SCREENING
Clinical trial: Visual Attention to Text and Pictorial Food Labels: An Eye Tracking Experiment
Status: COMPLETED
Conditions: Health Behavior
Interventions: BEHAVIORAL: Text only sodium label|BEHAVIORAL: Icon sodium label|BEHAVIORAL: Pictorial sodium label|BEHAVIORAL: Barcode label
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Bioequivalence Study Comparing A Fixed Dose Combination Formulation Of Myrin P Forte That Contains Rifampicin, Isoniazid, Ethambutol And Pyrazinamide Per Tablet To An Equivalent Dose Of Single Drug Reference Preparations Of Similar Combination Following Oral Administration In Healthy Adults
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Myrin P Forte|DRUG: Single drug references
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Trial Investigating the Pharmacokinetic and Pharmacodynamic Properties of FIAsp When Administered as a Bolus in a Continuous Subcutaneous Infusion Regimen in Subjects With Type 1 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 1
Interventions: DRUG: Faster-acting insulin aspart|DRUG: insulin aspart
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Microbial Species & Antibiotic Resistance ID in ED Patients Presenting With Infection - is Rapid ID Possible & Accurate?
Status: RECRUITING
Conditions: Sepsis|Systemic Inflammatory Response Syndrome|Infection Mixed|Infection, Bacterial|Infection, Fungal|Infection, Coronavirus
Interventions: DEVICE: Gene Z or other rapid diagnostic techniques developed in our lab (as of 2018 not using Gene Z regularly)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Chemotherapy With or Without Dalteparin in Treating Patients With Metastatic Pancreatic Cancer
Status: TERMINATED
Conditions: Chemotherapeutic Agent Toxicity|Pancreatic Cancer|Thromboembolism
Interventions: DRUG: daltéparine|DRUG: Chemotherapy at the investigator's discretion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: 3D-biomodels for Surgical Planning in Patients With Renal Cancer and Vascular Involvement
Status: UNKNOWN
Conditions: Renal Cell Carcinoma|Three-Dimensional|Venous Thromboses
Interventions: DEVICE: 3D printing + images|OTHER: Images
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Task Shifting in the Care for Patients With Hand Osteoarthritis
Status: COMPLETED
Conditions: Osteoarthritis Both Hands
Interventions: BEHAVIORAL: Rheumatologist-led care.|BEHAVIORAL: Occupational therapist-led care.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Self-control Trial to Evaluate the Remission Rate in Newly Diagnosed Type 2 Diabetes Patients After Treatment With Insulin Aspart
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: insulin aspart|DRUG: insulin NPH
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Role of Artery-Preserving Varicocelectomy in Subfertile Men With Severe Oligozoospermia.
Status: COMPLETED
Conditions: Infertility, Male|Oligozoospermia|Varicocelectomy
Interventions: PROCEDURE: artery preserving varicocelectomy|PROCEDURE: artery ligation varicocelectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Impact of Hyperoxia and Involvement of the Immune System in Diving Accident
Status: RECRUITING
Conditions: Decompression Sickness
Interventions: PROCEDURE: Hyperbaric oxygen therapy|PROCEDURE: Diving simulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effects of Neprilysin on Glucagon-like Peptide-1
Status: COMPLETED
Conditions: Diabetes|Heart Failure
Interventions: DRUG: Entresto|DRUG: Sitagliptin 100mg|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intrathecal Morphine,Femoral Nerve Block,Periarticular Bupivacaine Infiltration for Pain After Intramedullary Hip Screw
Status: UNKNOWN
Conditions: Femoral Neck Fractures
Interventions: DRUG: Bupivacaine, morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Feasibility of Liver Retraction With the Levita Magnetic Surgical System: Extended Magnetic Grasper Device
Status: RECRUITING
Conditions: Bariatric Surgery Candidate|Hiatal Hernia
Interventions: DEVICE: Extended Magnetic Grasper Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effect Of Strength Exercise on Respiratory Parameters, and Functional Capacity in Bariatric Surgery Patients
Status: COMPLETED
Conditions: Obesity, Morbid
Interventions: OTHER: Resistance Exercise Training|OTHER: Inspiratory Muscle Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Enhancing Nutrition and Antenatal Infection Treatment for Maternal and Child Health in Ethiopia
Status: WITHDRAWN
Conditions: Low Birthweight|Preterm Birth|Maternal; Malnutrition, Affecting Fetus|Sexually Transmitted Diseases|Urinary Tract Infections|Pregnancy and Infectious Disease
Interventions: DRUG: Azithromycin 500 mg|DIETARY_SUPPLEMENT: Multiple Micronutrient or Fortified Balanced Energy Protein Supplement|DRUG: Placebo oral tablet 500 mg|OTHER: Enhanced Infection Management Package (EIMP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of Pembrolizumab (MK-3475) Plus Carboplatin and Paclitaxel as First-line Treatment of Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma (MK-3475-B10/KEYNOTE B10)
Status: COMPLETED
Conditions: Squamous Cell Carcinoma of Head and Neck
Interventions: DRUG: Pembrolizumab|DRUG: Carboplatin|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Modified HFNC Oxygen in Patients Undergoing Bronchoscopy.
Status: COMPLETED
Conditions: Bronchoscopy,Oxygen
Interventions: DEVICE: Modified High-flow nasal cannula|DEVICE: nasal cannula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: VRS-317 in Adult Subjects With Growth Hormone Deficiency
Status: COMPLETED
Conditions: Growth Hormone Deficiency
Interventions: DRUG: VRS-317|DRUG: VRS-317|DRUG: VRS-317|DRUG: VRS-317|DRUG: VRS-317
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Validating Egg-based Diagnostics and Molecular Markers for the Spread of Anthelmintic Resistance
Status: COMPLETED
Conditions: Soil-transmitted Helminth Infections
Interventions: DRUG: Albendazole Pill 400mg (GSK)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Single Dose Escalation Study of ONO-9054 in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Adult Subjects
Interventions: DRUG: ONO-9054|DRUG: ONO-9054|DRUG: ONO-9054|DRUG: ONO-9054|DRUG: ONO-9054|DRUG: ONO-9054|DRUG: ONO-9054
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of LID104 in the Treatment of Type II Diabetes Mellitus
Status: NOT_YET_RECRUITING
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: LID104|DRUG: Dapagliflozin|DRUG: Linagliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Self-Collection of the Pap Smear as Agency: A Novel Way to Improve Refractory Low Cervical Cancer Screening Rates in Rural Alabama
Status: RECRUITING
Conditions: Cervical Cancer
Interventions: DIAGNOSTIC_TEST: Self-PAP|DIAGNOSTIC_TEST: Traditional Pap smear
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Optimization of Treatment in Patients With Severe Peripheral Ischemia (Fontaine Stage IIb)
Status: COMPLETED
Conditions: Peripheral Arterial Disease
Interventions: DRUG: iloprost|DRUG: Standard Treatment (aspirin.....),
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Beta-glucan on Energy Intake and Satiety
Status: UNKNOWN
Conditions: Obesity
Interventions: DIETARY_SUPPLEMENT: Oatwell28 Oatwell Original Powder|DIETARY_SUPPLEMENT: Control Breakfast
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Point of Care UltraSound (POCUS) Use for Intravenous Catheter Placement During Pediatric Interfacility Transport
Status: UNKNOWN
Conditions: Intravenous Access
Interventions: PROCEDURE: Butterfly iQ+ Ultrasound|PROCEDURE: Traditional
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exploratory Study Therapeutic Fasting Reduce Physical Limitations, Quality of Life During Aromatase Inhibitor Therapy
Status: RECRUITING
Conditions: Breast Cancer Patients Treated With Aromatase Inhibitors
Interventions: OTHER: Fasting
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Parathyroid and Thymus Transplantation in DiGeorge #931
Status: COMPLETED
Conditions: DiGeorge Syndrome|Hypoparathyroidism|Complete DiGeorge Syndrome
Interventions: BIOLOGICAL: Thymus/Parathyroid Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dual Therapy With Vonoprazan Plus Amoxicillin or Doxycycline Versus Bismuth Quadruple Therapy for Helicobacter Pylori Eradication:A Prospective, Multicenter, Open-label Randomized Controlled Study.
Status: NOT_YET_RECRUITING
Conditions: Helicobacter Pylori Infection
Interventions: DRUG: Vonoprazan+amoxicillin+doxycycline+bismuth for 14 days|DRUG: Vonoprazan+Amoxicillin|DRUG: Vonoprazan+doxycycline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Single Dose Citalopram and Reboxetine on Urethral and Anal Closure Function on Healthy Female Subjects
Status: COMPLETED
Conditions: Stress Urinary Incontinence|Fecal Incontinence
Interventions: DRUG: Citalopram 40mg|DRUG: Reboxetine 8 mg|DRUG: Placebo oral tablet|DRUG: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Short Term Comparative Study of Xalatan With Benzalkonium Chloride vs. Travatan Z Without Benzalkonium Chloride in Healthy Volunteers
Status: COMPLETED
Conditions: Glaucoma
Interventions: DRUG: Travatan® Z|DRUG: Xalatan®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Oncology Care at Home for BMT and CAR-T
Status: ACTIVE_NOT_RECRUITING
Conditions: Leukemia
Interventions: OTHER: BioIntelliSense BioButton Rechargable|OTHER: Memora Health two-way patient engagement platform provided by RC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Distribution of a Single IV Dose Of [124I]-Pf 06687234 and Pf 06687234 Assessed With PET-CT Imaging In Moderate To Severe Ulcerative Colitis and Crohn's Disease
Status: WITHDRAWN
Conditions: Inflammatory Bowel Disease
Interventions: BIOLOGICAL: PF 06687234|BIOLOGICAL: [124I]IB PF 06687234
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Effect Of Virtual Reality Glasses Applied During Pap Smear On Anxiety, Pain And Patient Satisfaction
Status: RECRUITING
Conditions: Anxiety|Pain|Patient Satisfaction
Interventions: DEVICE: Virtual Reality Glasses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: How Does the Clinical Tool 'What's Going Around' Affect Clinical Practice
Status: COMPLETED
Conditions: Influenza Like Illness|Asthma|Group A Streptococcal Infection|Pertussis
Interventions: OTHER: What's Going Around tool|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Engaging Sexual and Gender Minority Cigarette Smokers Into Social Media-based Treatment
Status: COMPLETED
Conditions: Smoking Cessation|Nicotine Dependence|Tobacco Use|Cigarette Smoking
Interventions: BEHAVIORAL: Social media-based education, counseling, and support|OTHER: Nicotine replacement therapies (NRT)|OTHER: Gamification
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to See if Platelet Transfusion Stop or Lessen the Effect of the Drug on Platelets
Status: COMPLETED
Conditions: Inhibition on Platelet Aggregation
Interventions: DRUG: Ticagrelor|DRUG: Clopidogrel|DRUG: ASA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Magnetic Resonance Imaging (MRI) to Predict Outcomes of Pancreatic Ductal Adenocarcinoma (PDAC)
Status: RECRUITING
Conditions: PDAC - Pancreatic Ductal Adenocarcinoma
Interventions: DIAGNOSTIC_TEST: 6D-MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Changes in Nasal Patency With Changes in Posture, Temperature, Humidity and Nasal Patency Seen by Acoustic Rhinometry
Status: COMPLETED
Conditions: Mucosal Congestion
Interventions: PROCEDURE: Acoustic rhinometry (procedure)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Catheter Ablation vs. Standard Conventional Treatment in Patients With LV Dysfunction and AF
Status: COMPLETED
Conditions: Atrial Fibrillation|Heart Failure
Interventions: PROCEDURE: Radiofrequency ablation|OTHER: Conventional treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Capsulotomy by Linear Accelerator Radiosurgery in Severe and Refractory Obsessive-compulsive Disorder
Status: UNKNOWN
Conditions: OCD|Quality of Life
Interventions: RADIATION: Radiosurgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Human Models of Selective Insulin Resistance: Alpelisib, Part I
Status: RECRUITING
Conditions: Insulin Resistance|Prediabetic State|Overweight and Obesity|Non-Alcoholic Fatty Liver Disease
Interventions: DRUG: Alpelisib 300 mg|DRUG: Placebo|DRUG: [1-13C] sodium acetate|DRUG: [6,6-2H2] D-glucose|DIETARY_SUPPLEMENT: Nestlé BOOST Plus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Drug Exposure and Minimum Inhibitory Concentration in the Treatment of MAC Lung Disease
Status: RECRUITING
Conditions: Mycobacterium Avium Complex|Mycobacterium Avium-Intracellulare Infection|Gram-Positive Bacterial Infections|Mycobacterium Infections
Interventions: OTHER: Drug exposure
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Bevacizumab Versus Ranibizumab in Treatment of Macular Edema From Vein Occlusion
Status: COMPLETED
Conditions: Retinal Vein Occlusion|Macular Edema
Interventions: DRUG: Intravitreal injection of bevacizumab|DRUG: Intravitreal injection of ranibizumab (0.5 mg per dose)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: C1 Esterase Inhibitor (C1INH-nf) for the Prevention of Acute Hereditary Angioedema (HAE) Attacks
Status: COMPLETED
Conditions: Hereditary Angioedema
Interventions: BIOLOGICAL: C1 esterase inhibitor [human] (C1INH-nf)|DRUG: Placebo (saline)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Cognitive-Behavioral Therapy With Exercise Training in Adolescent Females With Elevated Depression Symptoms
Status: ENROLLING_BY_INVITATION
Conditions: Depression
Interventions: BEHAVIORAL: Cognitive-Behavioral Therapy|OTHER: Exercise Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: TReatment Strategy In Acute Ischemic larGE Vessel STROKE: Prioritize Thrombolysis or Endovascular Treatment
Status: COMPLETED
Conditions: Stroke
Interventions: BEHAVIORAL: Primary Stroke Center (PSC)|BEHAVIORAL: Comprehensive Stroke Center (CSC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Zolendronate for the Prevention of Bone Loss in Men w/ Prostate CA on Long-Term Androgen Deprivation
Status: TERMINATED
Conditions: Osteoporosis|Prostate Cancer
Interventions: DIETARY_SUPPLEMENT: cholecalciferol|DRUG: calcium gluconate|DRUG: zoledronic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Multicenter, Open-label Extension Study to Assess the Long-term Safety and Efficacy of an Oral Calcimimetic Agent AMG 073 (Cinacalcet) in Primary Hyperparathyroidism
Status: COMPLETED
Conditions: Hyperparathyroidism, Primary
Interventions: DRUG: cinacalcet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Cerebral & Peripheral Electrical Stimulation on Pain and Function in CTS
Status: UNKNOWN
Conditions: Carpal Tunnel Syndrome
Interventions: DEVICE: tDCS-r|DEVICE: TENS-r|DEVICE: tDCS-s|DEVICE: TENS-s
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy in Treating Patients With Locally Advanced or Metastatic Cancer of the Pancreas or Bile Duct
Status: UNKNOWN
Conditions: Extrahepatic Bile Duct Cancer|Pancreatic Cancer
Interventions: DRUG: fluorouracil|DRUG: gemcitabine hydrochloride|DRUG: leucovorin calcium|PROCEDURE: conventional surgery|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Transcutaneous Vagal Nerve Stimulation: Influence on miRNA, Inflammation, Cerebral Resting State and Gastric Motility
Status: COMPLETED
Conditions: Epilepsy
Interventions: DEVICE: Transcutaneous vagal nerve stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Curative Effect of Entecavir Combined Resveratrol on HBV patients-a Multi-center, Random, Open Clinical Trial
Status: COMPLETED
Conditions: Hepatitis
Interventions: DRUG: entecavir+resveratrol|DRUG: Entecavir|DRUG: entecavir+thymosin α1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Leveraging Infant Visit PrEP INtegration & tasK Shifting to Improve Post-partum HIV Prevention in Malawi
Status: NOT_YET_RECRUITING
Conditions: Breastfeeding|HIV Prevention
Interventions: BEHAVIORAL: LINK model
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Pharmacokinetic, Safety and Tolerability Study of Altebrel in Healthy Male Subjects
Status: COMPLETED
Conditions: Phase 1|Bioequivalence
Interventions: DRUG: Etanercept
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Trial of AMG 479, Everolimus (RAD001) and Panitumumab in Patients With Advanced Cancer - QUILT-3.007
Status: COMPLETED
Conditions: Advanced Solid Tumors, Non-small Cell Lung Cancer
Interventions: DRUG: AMG 479, Everolimus, Panitumumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Anlotinib Combined With or Without PD-1 Antibody on Unresectable High-grade Chondrosarcoma
Status: RECRUITING
Conditions: Chondrosarcoma
Interventions: DRUG: Anlotinib hydrochloride|DRUG: PD-1 inhibitor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of a Physical Therapy Telerehabilitation Program in Long Post COVID-19 Symptoms in Primary Health Care.
Status: COMPLETED
Conditions: COVID-19|Physical Therapy Modalities|Telerehabilitation|Primary Health Care
Interventions: OTHER: Physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: HSI for Intersegmental Plane Identification During Sublobar Pulmonary Resections
Status: NOT_YET_RECRUITING
Conditions: Lung Neoplasm|Pulmonary Metastasis
Interventions: DEVICE: Hyperspectral Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Investigating Transcranial Ultrasound as a Potential Intervention for Depression
Status: COMPLETED
Conditions: Depression|Anxiety Disorders
Interventions: DEVICE: Transcranial Ultrasound Power|DEVICE: Transcranial Ultrasound Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Palliative Care in Improving Quality of Life in Patients With High Risk Primary or Recurrent Gynecologic Malignancies
Status: COMPLETED
Conditions: Cervical Carcinoma|Ovarian Carcinoma|Primary Peritoneal Carcinoma|Recurrent Cervical Carcinoma|Recurrent Ovarian Carcinoma|Recurrent Uterine Corpus Carcinoma|Recurrent Vulvar Carcinoma|Uterine Corpus Cancer|Vulvar Carcinoma|Peritoneal Neoplasms
Interventions: OTHER: Palliative Therapy|OTHER: Palliative Therapy + idiographic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of a Music-Based Multitask Exercises Program on Gait, Balance and Fall Risk in the Elderly
Status: COMPLETED
Conditions: Gait|Balance|Falls
Interventions: OTHER: Music-based multitask exercises program|OTHER: Music-based multitask exercises program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Atosiban Versus Placebo in the Treatment of Late Threatened Pre-term Birth
Status: COMPLETED
Conditions: Preterm Birth
Interventions: DRUG: Atosiban
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Modulating Human Cortical Plasticity With Transcranial Electrical Stimulation
Status: COMPLETED
Conditions: Healthy|Schizophrenia
Interventions: DEVICE: tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Neuropathic Pain and Operant Conditioning of Cutaneous Reflexes After SCI
Status: RECRUITING
Conditions: Spinal Cord Injuries|Neuropathic Pain|Neurological Injury|Pain
Interventions: BEHAVIORAL: Operant Conditioning of Cutaneous Reflexes
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of a Sequential Treatment Strategy in Rheumatoid Arthritis
Status: RECRUITING
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Abatacept (W12-W48)|DRUG: TNF Inhibitor (W12-W48)|DRUG: TNF Inhibitor (W0-W12)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mild Hypothermia and Supplemental Magnesium Sulfate Infusion in Severe Traumatic Brain Injury (TBI) Subjects
Status: TERMINATED
Conditions: Traumatic Brain Injury
Interventions: DEVICE: Arctic Sun|DRUG: Magnesium Sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study on Effects of a Dairy Product Based on Polyphenols and Enriched With Vitamins B6, B9 and B12 on Some Cardiovascular Factor of Risk
Status: COMPLETED
Conditions: Cardiovascular Risk Factors
Interventions: DIETARY_SUPPLEMENT: Vitamins B6, B9 and B12 and polyphenols|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Prospective Cohort Study Comparing AI Prediction Model With Imaging Assessment to Diagnose Lymph Node Metastasis in Cervical Cancer
Status: NOT_YET_RECRUITING
Conditions: Uterine Cervical Neoplasms
Interventions: DIAGNOSTIC_TEST: AI Prediction Model|DIAGNOSTIC_TEST: Conventional Imageing Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Ultrasound-guided Selective Shoulder Block Versus Ultrasound-guided Interscalene Brachial Plexus Block, an RCT
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: PROCEDURE: Interscalene block|PROCEDURE: Selective shoulder block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Long-Term Outcomes of Patients With Acute Lymphoblastic Leukemia Who Were Enrolled as Children on Clinical Trials EORTC-58741, EORTC-58831, EORTC-58832, or EORTC-58881 Between 1971 and 1998
Status: UNKNOWN
Conditions: Cancer Survivor|Leukemia|Long-term Effects Secondary to Cancer Therapy in Children
Interventions: OTHER: medical chart review|OTHER: questionnaire administration|OTHER: study of socioeconomic and demographic variables
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Aging With Long Term Physical Disabilities
Status: ACTIVE_NOT_RECRUITING
Conditions: Physical Disability
Interventions: BEHAVIORAL: Removing Environmental Barriers to Independent Living (REBIL)|BEHAVIORAL: Waitlist Attentional Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Etrasimod Versus Placebo for the Treatment of Moderately to Severely Active Ulcerative Colitis
Status: COMPLETED
Conditions: Ulcerative Colitis
Interventions: DRUG: Etrasimod|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Emergence Agitation and Pain Scores in Pediatrics When Comparing Single-modal vs Multi-modal Analgesia for ENT Surgery
Status: COMPLETED
Conditions: Emergence Agitation|Pain
Interventions: DRUG: IV acetaminophen|DRUG: Fentanyl|DRUG: PO acetaminophen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Maraviroc-Based GVHD Prophylaxis in HLA-Unrelated and HLA-Mismatched Related Transplantation
Status: UNKNOWN
Conditions: Graft-versus-host Disease|Hematopoietic Stem Cell Transplantation
Interventions: DRUG: Maraviroc|DRUG: Cyclosporine (in HLA-Unrelated Donor Transplantation)|DRUG: Tacrolimus (in HLA-Mismatched Related Donor Transplantation)|DRUG: Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Vascular Impact of Omega-3 in Metabolic Syndrome
Status: COMPLETED
Conditions: Essential Hypertension|Metabolic Syndrome
Interventions: DIETARY_SUPPLEMENT: omega-3 from vegetal origin|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Integrated Research on Acute Malnutrition in Mali (IRAM-MALI)
Status: COMPLETED
Conditions: Acute Malnutrition in Childhood|Wasting
Interventions: BEHAVIORAL: Strengthened SBCC|DIETARY_SUPPLEMENT: Preventive nutritional supplement|BEHAVIORAL: Family MUAC|BEHAVIORAL: Active screening by NASGs|BEHAVIORAL: Intensified followup of children with wasting referred to and enrolled in CMAM treatment|BEHAVIORAL: Relapse prevention|BEHAVIORAL: Cooking demonstrations
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Dose Escalation Study Of Palifermin in Pediatric Research Participants Undergoing Allogeneic Hematopoietic Stem Cell Transplantation
Status: COMPLETED
Conditions: Oral Mucositis|Hematopoietic Stem Cell Transplantation
Interventions: DRUG: Palifermin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Concurrent Chemoradiotherapy With Toripalimab for Local-regional Recurrent Nasopharyngeal Carcinoma: a Prospective, Single-arm, Phase II Trial
Status: UNKNOWN
Conditions: Nasopharyngeal Carcinoma|Toripalimab|Recurrent Nasopharyngeal Squamous Cell Carcinoma
Interventions: DRUG: Toripalimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Community-Based Trial of Screening for Chlamydia Trachomatis to Prevent Pelvic Inflammatory Disease
Status: COMPLETED
Conditions: Pelvic Inflammatory Disease|Chlamydia Infections
Interventions: PROCEDURE: Screening for chlamydia using self-taken vaginal swabs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION