pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Evaluation of High Velocity Nasal Insufflation in Management of Respiratory Failure in Patients With Overlap Syndrome
Status: UNKNOWN
Conditions: Overlap Syndrome|Obesity Hypoventilation Syndrome
Interventions: OTHER: High Velocity Nasal Insufflation|OTHER: Non-invasive mechanical ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Tideglusib for the Treatment of Amyotrophic Lateral Sclerosis
Status: NOT_YET_RECRUITING
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DRUG: Tideglusib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Telerehabilitation Program for Improvement of Upper Limb Function Among Adults Post Elbow Fractures
Status: UNKNOWN
Conditions: Elbow Fractures
Interventions: OTHER: Telerehabilitation|OTHER: Rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II Study of Ipilimumab Monotherapy in Recurrent Platinum-sensitive Ovarian Cancer
Status: COMPLETED
Conditions: Platinum-sensitive Ovarian Cancer, Second-line, Third-line, or Fourth-line
Interventions: BIOLOGICAL: Ipilimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Added Value of Contrast Enhanced Mammography to Standard Mammography in Assessing the Extent of DCIS
Status: NOT_YET_RECRUITING
Conditions: DCIS|Breast Carcinoma in Situ|Calcification
Interventions: DIAGNOSTIC_TEST: Contrast Enhanced Mammography
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study Of New Medicine (GSK 372475) For The Treatment Of Depression
Status: COMPLETED
Conditions: Depressive Disorder
Interventions: DRUG: GSK372475|DRUG: venlafaxine|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tipifarnib in Treating Patients With Chronic Myeloid Leukemia, Chronic Myelomonocytic Leukemia, or Undifferentiated Myeloproliferative Disorders
Status: COMPLETED
Conditions: Accelerated Phase of Disease|Atypical Chronic Myeloid Leukemia, BCR-ABL1 Negative|Chronic Myelogenous Leukemia, BCR-ABL1 Positive|Chronic Myelomonocytic Leukemia|Chronic Phase of Disease|Myelodysplastic/Myeloproliferative Neoplasm, Unclassifiable|Recurrent Disease
Interventions: OTHER: Laboratory Biomarker Analysis|DRUG: Tipifarnib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Light Curable Resin Modified Glass Ionomer Varnish on Non-Cavitated Proximal Carious Lesions' Progression
Status: UNKNOWN
Conditions: Dental Caries|Dental White Spot
Interventions: DEVICE: Light curable resin modified glass ionomer varnish|OTHER: standard-of-care preventive measures
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: AIDS Vaccine Study Comparing Immunogenicity and Safety of 3 Doses of Lipopeptides Versus Placebo in Non Infected HIV Volunteers
Status: COMPLETED
Conditions: HIV Infections
Interventions: BIOLOGICAL: LIPO-5
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Comparison of Excision Versus Punch Incision in the Treatment of Epidermal Cysts
Status: COMPLETED
Conditions: Epidermal Cyst
Interventions: PROCEDURE: Excisional surgery of epidermal cyst|PROCEDURE: Punch incision of epidermal cyst
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigating the Effects of a High GI Versus a Low GI Diet on Hepatic Metabolism and Satiety Levels in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: High/Low Glycaemic index test breakfast
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Clinical Trial of Efficacy and Safety of Anaferon for Children Liquid Dosage Form in the Treatment of Acute Upper Respiratory Infections
Status: COMPLETED
Conditions: Acute Upper Respiratory Infections
Interventions: DRUG: Anaferon for children (liquid dosage form)|DRUG: Placebo (liquid dosage form)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment for Mild Hip Dysplasia in Newborns
Status: COMPLETED
Conditions: Developmental Dysplasia of the Hip
Interventions: DEVICE: Abduction treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Autologous, Culture-Expanded Mesenchymal Stromal Cells for Degenerative Disc Disease
Status: TERMINATED
Conditions: Degenerative Disc Disease
Interventions: DRUG: Autologous Adipose-Derived Mesenchymal Stromal Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Prospective, Descriptive Cohort Study With Prontosan® Wound Gel X in Partial and Full Thickness Burns Requiring Split Thickness Skin Grafts
Status: COMPLETED
Conditions: Burns
Interventions: DEVICE: Prontosan Wound Gel X
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of Effects of Intravenous Midazolam and Ketamine on Emergence Agitation
Status: COMPLETED
Conditions: Psychomotor Agitation
Interventions: DRUG: Midazolam|DRUG: Ketamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Generalized Versus Core Stabilization Antenatal Exercises For Lumbopelvic Pain
Status: COMPLETED
Conditions: Low Back Pain|Pelvic Pain
Interventions: OTHER: Core Stabalization Exercises|OTHER: Generalized Antenatal Exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Emollients in the Management of Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: glycerol, paraffin (liquid and white soft)|DEVICE: Atopiclair®|DRUG: Locatop@|DRUG: Locapred@
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Visual Function Changes After Intraocular Pressure Reduction
Status: COMPLETED
Conditions: Glaucoma
Interventions: DRUG: timolol maleate 0,5%|DRUG: brimonidine tartrate 0,2%|DRUG: travoprost 0,004%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Safety of Intramuscular Injection of Allogeneic PLX-PAD Cells for the Treatment of Critical Limb Ischemia
Status: COMPLETED
Conditions: Peripheral Artery Disease|Peripheral Vascular Disease|Critical Limb Ischemia
Interventions: BIOLOGICAL: PLX-PAD IM injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chocolate for Patients With Chronic Kidney Disease
Status: COMPLETED
Conditions: Chronic Kidney Disease
Interventions: DIETARY_SUPPLEMENT: Dark Chocolate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Pemetrexed (Alimta) in Patients With Head and Neck Squamous Cell Cancer
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: DRUG: Pemetrexed|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Chemotherapy With SEEOX Regimen for Borrmann Type 4 Gastric Cancer
Status: UNKNOWN
Conditions: Stomach Neoplasms|Gastric Cancer
Interventions: DRUG: oxaliplatin|DRUG: etoposide|DRUG: epirubicin|DRUG: S1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Symbicort® Single Inhaler Therapy and Conventional Best Practice for the Treatment of Persistent Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Symbicort TBH - Turbuhaler|DRUG: beta-II-agonist, inhale steroid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness and Safety of Collagen Complex COLLOST in Anti-age Therapy
Status: COMPLETED
Conditions: Skin Aging
Interventions: DEVICE: Collagen for injections 7%|DEVICE: Hyaluronic acid for injections 2%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Validation of New Markers of Glomerular Filtration Rate: Dota Gadolinium and Calcium EDTA (MultiGFR)
Status: TERMINATED
Conditions: Renal Insufficiency, Chronic|Kidney Diseases
Interventions: DRUG: Calcium EDTA|DRUG: Gd-DOTA
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: RELIEF Study: Real-world Evaluation of LUTS Interventions and Patient Experience During Follow-up
Status: NOT_YET_RECRUITING
Conditions: Benign Prostatic Hyperplasia
Interventions: DEVICE: UroLift System|OTHER: Watchful Waiting or BPH Medications|DEVICE: Other Surgical Intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy of Doxycycline Prophylaxis to Reduce Syphilis in High-Risk, HIV-Positive MSM
Status: COMPLETED
Conditions: Syphilis
Interventions: DRUG: Doxycycyline|BEHAVIORAL: Incentive
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Testing the Combination of DS-8201a and Olaparib in HER2-Expressing Cancers With Expansion in Patients With Endometrial Cancer
Status: SUSPENDED
Conditions: Endometrial Serous Adenocarcinoma|Metastatic Malignant Solid Neoplasm|Unresectable Malignant Solid Neoplasm
Interventions: PROCEDURE: Biopsy|PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|PROCEDURE: Echocardiography|DRUG: Olaparib|BIOLOGICAL: Trastuzumab Deruxtecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Video Education on Patients' Knowledge and Attitudes of Privacy in Prenatal Genetics
Status: COMPLETED
Conditions: Aneuploidy|Genetic Disease|Pregnancy Related
Interventions: BEHAVIORAL: Enhanced (experimental) education|BEHAVIORAL: Standard (control) education.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Long Term Immunogenicity Study of Engerix-B Vaccine in 10 Year Old Children and the Effect of Booster Injections
Status: COMPLETED
Conditions: Hepatitis B|Vaccination
Interventions: BIOLOGICAL: Engerix-B
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Characteristics of the Vergence Responses of Binocularly Normal Subjects After a Vision Therapy Protocol
Status: UNKNOWN
Conditions: Vision Disorders|Eye; Movement Disorder (Binocular)|Vision Therapy|Binocular Vision Disorder
Interventions: OTHER: Experimental: Classical Vision Therapy Treatment|OTHER: Control: Eye Movement Therapy Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Home-based Electronic Cognitive Therapy in Alzheimer's Disease
Status: TERMINATED
Conditions: Memory Disorders|Mild Cognitive Impairment|Alzheimer's Disease
Interventions: BEHAVIORAL: Intervention Group|BEHAVIORAL: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Indomethacin Use in Pain Relief During Intrauterine Device Insertion
Status: COMPLETED
Conditions: Family Planning
Interventions: DRUG: indomethacin suppositories|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Prospective Clinical Study of BTK Inhibitor, PD-1 and Formustine in the First-line Treatment of Primary Central Nervous System Lymphoma
Status: RECRUITING
Conditions: Primary Central Nervous System Lymphoma
Interventions: DRUG: the dose-escalation phase
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Laser Therapy and Temporomandibular Disorders
Status: RECRUITING
Conditions: TMD
Interventions: OTHER: Nd YAG laser|OTHER: diode laser (980 nm)|OTHER: diode laser (940 nm)|OTHER: diode laser (660 nm)|OTHER: diode laser (635 nm)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study Comparing Veliparib Plus FOLFIRI Versus Placebo Plus FOLFIRI With or Without Bevacizumab in Previously Untreated Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Untreated Metastatic Colorectal Cancer
Interventions: DRUG: Veliparib|DRUG: Placebo|DRUG: Modified FOLFIRI|DRUG: FOLFIRI|DRUG: Bevacizumab|DRUG: Fluorouracil infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Metabolic Health on Sperm Epigenetic Marks in Humans
Status: RECRUITING
Conditions: Overweight|Type 2 Diabetes Mellitus|Type 1 Diabetes Mellitus
Interventions: OTHER: Lifestyle Intervention|OTHER: No Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Self-activation in Individuals With and Without Nicotine Dependence
Status: TERMINATED
Conditions: Addiction Nicotine
Interventions: DEVICE: Neurofeedback (from fMRI and/or EEG)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Computerized Substance Use and Depression Screening and Behavioral Treatment in HIV Primary Care
Status: COMPLETED
Conditions: Substance Use Disorders|HIV|Depression|Anxiety
Interventions: BEHAVIORAL: Clinic-based screening and behavioral interventions
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Nivolumab in Treating Patients With Recurrent and/or Metastatic Nasopharyngeal Cancer
Status: COMPLETED
Conditions: Nasopharyngeal Nonkeratinizing Carcinoma|Recurrent Nasopharynx Carcinoma|Stage III Nasopharyngeal Carcinoma AJCC v7|Stage IV Nasopharyngeal Carcinoma AJCC v7|Stage IVA Nasopharyngeal Carcinoma AJCC v7|Stage IVB Nasopharyngeal Carcinoma AJCC v7|Stage IVC Nasopharyngeal Carcinoma AJCC v7
Interventions: OTHER: Laboratory Biomarker Analysis|BIOLOGICAL: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Abatacept to Silence Anti-citrullinated Protein Antibody-expressing B Cells in Rheumatoid Arthritis (ASCARA)
Status: COMPLETED
Conditions: Rheumatoid Arthritis|Rheumatic Diseases
Interventions: DRUG: Abatacept|DRUG: Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Remote Ischemic Conditioning on Cerebral Hemodynamics in Patients After Intravenous Thrombolysis (RICCH-IVT)
Status: COMPLETED
Conditions: Remote Ischemic Conditioning
Interventions: PROCEDURE: Remote ischemic conditioning|PROCEDURE: Sham remote ischemic conditioning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Aom0319 SAD Study in Healthy Subjects
Status: RECRUITING
Conditions: Healthy Volunteers
Interventions: DRUG: Adamgammadex Sodium|DRUG: 0.9% Sodium Chloride Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MRSA Eradication and Decolonization in Children
Status: TERMINATED
Conditions: MRSA
Interventions: OTHER: Hygiene education|OTHER: Sodium Hypochlorite|DRUG: Mupirocin ointment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Low Dose Versus High Dose Methylene Blue in Septic Patients
Status: COMPLETED
Conditions: Septic Shock
Interventions: DRUG: Normal saline|DRUG: Methylene Blue low dose|DRUG: Methylene Blue high dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Assessment Tool for Older Patients With Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Cognitive/Functional Effects|Psychosocial Effects of Cancer and Its Treatment|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: OTHER: questionnaire administration|PROCEDURE: cognitive assessment|PROCEDURE: psychosocial assessment and care
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Intravenous BI 6727 (Volasertib) in 2nd Line Treatment of Urothelial Cancer
Status: COMPLETED
Conditions: Neoplasms
Interventions: DRUG: BI 6727, IV infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Electroacupuncture in NMOSD Patients With Pain: Study Protocol
Status: COMPLETED
Conditions: Neuromyelitis Optica Spectrum Disorders|Pain
Interventions: BEHAVIORAL: electroacupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Dose-finding Study of RO5323441 in Patients With Metastatic Treatment-Refractory Colorectal or Ovarian Cancer
Status: COMPLETED
Conditions: Colorectal Cancer, Ovarian Cancer
Interventions: DRUG: RO5323441
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preventing Recurrent Gestational Diabetes With Metformin
Status: UNKNOWN
Conditions: Gestational Diabetes Mellitus
Interventions: DRUG: Metformin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: An Open-Label, Phase 2 Trial of Nanatinostat in Combination With Valganciclovir in Patients With Epstein-Barr Virus-Positive (EBV+) Relapsed/Refractory Lymphomas
Status: RECRUITING
Conditions: Epstein-Barr Virus Associated Lymphoproliferative Disorder|EBV-Related PTLD|EBV Related Non-Hodgkin's Lymphoma|EBV-Positive DLBCL, NOS|EBV Associated Lymphoma|EBV Related PTCL, NOS
Interventions: DRUG: Nanatinostat in combination with valganciclovir
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Neuropsychological Rehabilitation Program for Disease of Adaptation in Patients With Acquired Brain Injury and Caregivers
Status: RECRUITING
Conditions: Acquired Brain Injury|Neuropsychological Rehabilitation|Caregiver
Interventions: OTHER: Neuropsychological Rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: An Open Label Study of the Safety and Efficacy of Psilocybin in Participants With Treatment-Resistant Depression (P-TRD)
Status: ACTIVE_NOT_RECRUITING
Conditions: Treatment Resistant Depression
Interventions: DRUG: Psilocybin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Caries Removal in Primary Teeth Using Er:YAG Laser
Status: COMPLETED
Conditions: Dental Caries
Interventions: DEVICE: Er:YAG laser system (Doctor smile, Pluser, Italy)|DEVICE: Master Torque high/low-speed air rotor handpiece (KaVo Dental, Charlotte, North Carolina, USA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial to Compare the Efficacy of Two Formulations of Avotermin Against Placebo
Status: COMPLETED
Conditions: Scar Improvement
Interventions: DRUG: Juvista (Avotermin)|DRUG: RN1006 (Avotermin)|DRUG: RN1006 (Avotermin)|DRUG: RN1006 (Avotermin)|DRUG: Juvista (Avotermin)|DRUG: Juvista (Avotermin)|DRUG: Juvista (Avotermin)|DRUG: RN1006 (Avotermin)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Randomized Control Trial of Intracervical Balloon Placement vs Oxytocin in Women With Term PROM and Unripe Cervices
Status: WITHDRAWN
Conditions: Premature Rupture of Membrane|Unfavorable Cervix
Interventions: DEVICE: Intracervical balloon catheter|DRUG: Oxytocin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Conditioning Regimen of Bendamustine and Melphalan Followed by Transplant in Patients With Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Bendamustine|DRUG: Melphalan|DRUG: Bendamustine|DRUG: Bendamustine|DRUG: Bendamustine|DRUG: Bendamustine|DRUG: Bendamustine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioavailability Pilot Study of Versus W0035 Versus Stromectol
Status: WITHDRAWN
Conditions: Healthy Volunteers
Interventions: DRUG: ivermectin T1|DRUG: ivermectin T2|DRUG: ivermectin T3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Kids FACE FEARS Comparative Effectiveness Research
Status: COMPLETED
Conditions: Child Anxiety|Anxiety Disorder of Adolescence
Interventions: BEHAVIORAL: Therapist-led Face-to-Face Cognitive-Behavioral Therapy|BEHAVIORAL: Digital Cognitive-Behavioral Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Safety and Daytime Sedation in Subjects With Parkinson's Disease With Neuropsychiatric Symptoms Treated With Pimavanserin or Low-Dose Quetiapine
Status: TERMINATED
Conditions: Parkinson's Disease
Interventions: DRUG: Pimavanserin|OTHER: Placebo|DRUG: Quetiapine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of IORT With CT-Guided HDR Brachytherapy for Treatment of Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer
Interventions: DEVICE: IORT with CT-Guided HDR Brachytherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Zanubrutinib and Rituximab Followed by R-DHAOx Then Maintenance With Zanubrutinib for Newly-Diagnosed MCL
Status: RECRUITING
Conditions: Mantle Cell Lymphoma|Newly-diagnosed Mantle Cell Lymphoma
Interventions: DRUG: Zanubrutinib and Rituximab|DRUG: R-DHAOx|DRUG: Zanubrutinib Maintenance
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Photopheresis in Early-stage Mycosis Fungoides
Status: RECRUITING
Conditions: Cutaneous T Cell Lymphoma|Mycosis Fungoides
Interventions: DRUG: UVADEX® (methoxsalen) Sterile Solution in conjunction with the THERAKOS® CELLEX Photopheresis|DEVICE: THERAKOS® CELLEX photopheresis system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Protein Supplementation After ACL Surgery
Status: RECRUITING
Conditions: ACL Reconstruction
Interventions: DIETARY_SUPPLEMENT: Whey protein isolate|DIETARY_SUPPLEMENT: Protein + BAA|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Randomized Bioimpedance vs Clinical Methods in Guiding Ultrafiltration in Hemodialysis Patients
Status: COMPLETED
Conditions: Haemodialyzed Patients|Volume Status
Interventions: OTHER: Strict bioimpedance guided dry weight prescription
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Assessing AThrough Radiofrequency Transseptal Puncture System for Left Atrial Access
Status: COMPLETED
Conditions: Heart Diseases|Atrial Fibrillation
Interventions: DEVICE: AThrough radiofrequency transseptal puncture system|DEVICE: Traditional mechanical transseptal puncture needle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Actinium-225-Lintuzumab in Patients With Acute Myeloid Leukemia
Status: WITHDRAWN
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Ac-Lintuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Immune Phenotype Biomarkers in Patients With Relapsing Multiple Sclerosis (RMS) After Treatment With 0.5mg Fingolimod
Status: COMPLETED
Conditions: Relapsing Multiple Sclerosis
Interventions: DRUG: Fingolimod
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: An Information-Motivation-Behavioral Skills (IMB) Intervention to Promote Human Papillomavirus Vaccination Among Women
Status: COMPLETED
Conditions: Human Papillomavirus Infection
Interventions: BEHAVIORAL: IMB Intervention Group|BEHAVIORAL: Attention Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Testing the Addition of an Anti-cancer Drug, Ipatasertib, to the Usual Immunotherapy Treatment (Pembrolizumab) in Patients With Recurrent or Metastatic Squamous Cell Cancer of the Head and Neck
Status: RECRUITING
Conditions: Head and Neck Squamous Cell Carcinoma|Metastatic Head and Neck Squamous Cell Carcinoma|Metastatic Hypopharyngeal Squamous Cell Carcinoma|Metastatic Laryngeal Squamous Cell Carcinoma|Metastatic Oral Cavity Squamous Cell Carcinoma|Metastatic Oropharyngeal Squamous Cell Carcinoma|Recurrent Head and Neck Squamous Cell Carcinoma|Recurrent Hypopharyngeal Squamous Cell Carcinoma|Recurrent Laryngeal Squamous Cell Carcinoma|Recurrent Oral Cavity Squamous Cell Carcinoma|Recurrent Oropharyngeal Squamous Cell Carcinoma|Stage IV Hypopharyngeal Carcinoma AJCC v8|Stage IV Laryngeal Cancer AJCC v8|Stage IV Lip and Oral Cavity Cancer AJCC v8|Stage IV Oropharyngeal (p16-Negative) Carcinoma AJCC v8
Interventions: PROCEDURE: Biopsy|PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|DRUG: Ipatasertib|BIOLOGICAL: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: LFIT™ Anatomic CoCr Femoral Heads With X3® Polyethylene Insert Study
Status: COMPLETED
Conditions: Arthroplasty, Replacement, Hip
Interventions: DEVICE: LFIT™ Femoral Heads With X3® Insert
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Timed-Sequential Induction in CBF-AML
Status: COMPLETED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Chemotherapy (DAUNORUBICINE-CYTARABINE)|DRUG: Chemotherapy (DAUNORUBICINE-CYTARABINE)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Temporally-modulated Pulsed Radiation Therapy (TMPRT) After Prior EBRT for Recurrent IDH-mutant Gliomas
Status: RECRUITING
Conditions: Astrocytoma|Oligodendroglioma, Adult|Glioma, Malignant
Interventions: RADIATION: temporally-modulated pulsed radiotherapy (TMPRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sevoflurane Insufflation vs Intravenous Sedation for Radiotherapy in Pediatric Patients
Status: UNKNOWN
Conditions: Pediatric Sedation|Radiotherapy|Inhalation Anesthesia
Interventions: PROCEDURE: Sedation with sevoflurane insufflation|PROCEDURE: intravenous sedation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Clinical Study Evaluating the Efficacy and Safety of CID v2.2 in Glaucoma Surgery
Status: NOT_YET_RECRUITING
Conditions: Glaucoma, Open-Angle|Glaucoma, Narrow Angle
Interventions: DEVICE: Cilioscleral Interposition Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacodynamic & Safety of Patiromer in Children & Adolescents (2-<18 Yrs) With Chronic Kidney Disease and Hyperkalemia
Status: TERMINATED
Conditions: Hyperkalemia
Interventions: DRUG: Patiromer|DRUG: Patiromer|DRUG: Patiromer
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study of Inflammatory Markers in Alzheimer's Disease
Status: UNKNOWN
Conditions: Alzheimer's Disease
Interventions: DRUG: doxycycline|DRUG: rifampin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Trial Combining Pembrolizumab and Cesium 131 Brachytherapy With Salvage Surgery in HNSCC
Status: ACTIVE_NOT_RECRUITING
Conditions: HNSCC
Interventions: DEVICE: Cesium-131|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of 3-Week Consumption of Soya Beverage Enriched With Plant Sterols on Serum LDL-C
Status: COMPLETED
Conditions: Dyslipidemia
Interventions: DIETARY_SUPPLEMENT: Plant sterols-enriched soya beverage provided by Vitasoy|DIETARY_SUPPLEMENT: Soya beverage provided by Vitasoy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Concentric-eccentric Exercises in Patellofemoral Pain Syndrome
Status: RECRUITING
Conditions: Patello Femoral Syndrome|Patellofemoral Pain|Knee Pain Chronic
Interventions: OTHER: eccentric exercises|OTHER: concentric exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Electro-acupuncture (EA) in Children Undergoing Procedures for Congenital Heart Defects.
Status: COMPLETED
Conditions: Congenital Heart Defect
Interventions: DEVICE: electro-acupuncture (EA)|DEVICE: sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Program Using a Mobile Application Versus Telephone Advice on Patients at Risk of Coronary Heart Disease : a Pilot RCT
Status: UNKNOWN
Conditions: Coronary Heart Disease
Interventions: DEVICE: App support Programme (ASP) group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: HOPE: A Trial of Hydroxichloroquine Plus Azithromycin in High Risk COVID-19
Status: WITHDRAWN
Conditions: Sars-CoV2
Interventions: DRUG: Hydroxychloroquine and Azithromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Study Evaluating Twice-Daily Administration of Momelotinib in Primary Myelofibrosis or Post-Polycythemia Vera or Post-Essential Thrombocythemia Myelofibrosis
Status: COMPLETED
Conditions: Primary Myelofibrosis|Post-Polycythemia Vera|Post-Essential Thrombocythemia Myelofibrosis
Interventions: DRUG: Momelotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prophylactic Use of Filgrastim SD/01 in Patients With Hodgkin's Disease Receiving ABVD Chemotherapy
Status: COMPLETED
Conditions: Hodgkin Disease
Interventions: DRUG: Filgrastim SD/01|DRUG: Adriamycin|DRUG: Bleomycin|DRUG: Vinblastine|DRUG: DTIC
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Interdisciplinary Approach to the Treatment of Encopresis in Children With Autism Spectrum Disorders
Status: COMPLETED
Conditions: Encopresis|Autistic Disorder
Interventions: DRUG: Glycerin Suppository|DRUG: Bisacodyl suppository|DRUG: Senna
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Multiple Ascending Dose Study of BMS-650032 in HCV Infected Subjects
Status: COMPLETED
Conditions: Chronic Hepatitis C
Interventions: DRUG: BMS-650032|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Pharmacokinetic And Pharmacodynamic Study Of Oral Lenalidomide (Revlimid) In Subjects With Low- Or Intermediate-1-Risk Myelodysplastic Syndromes
Status: COMPLETED
Conditions: Low- or Intermediate-1-risk Myelodysplastic Syndrome (MDS)
Interventions: DRUG: Lenalidomide|DRUG: Recombinant human erythropoietin
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of CIN-107 in Adults With Treatment-Resistant Hypertension (rHTN)
Status: COMPLETED
Conditions: Resistant Hypertension
Interventions: DRUG: CIN-107|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study of Total Neoadjuvant Therapy for Locally Advanced Gastric Cancer
Status: UNKNOWN
Conditions: Gastric Cancer|Neoadjuvant Therapy
Interventions: RADIATION: SIB-IMRT|DRUG: S-1|DRUG: SOX|PROCEDURE: Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Self Help Program for Hypnotics Withdrawal in Insomniac Patients
Status: COMPLETED
Conditions: Insomnia
Interventions: OTHER: Standardized gradual hypnotic taper|BEHAVIORAL: Short-term simple self-help program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Immunogenicity of Recombinant Varicella Zoster Virus Vaccine in People With HIV Who Have a CD4 Count Less Than 300 or Greater Than or Equal to 300 and a Healthy Control Population
Status: RECRUITING
Conditions: Herpes Zoster
Interventions: BIOLOGICAL: Shingrix
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Immune Response to the Human Papillomavirus Vaccine in Young Women With Inflammatory Bowel Disease
Status: COMPLETED
Conditions: Inflammatory Bowel Disease|Uterine Cervical Dysplasia
Interventions: BIOLOGICAL: Human Papillomavirus Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Empagliflozin in Hypertrophic Cardiomyopathy
Status: RECRUITING
Conditions: Hypertrophic Cardiomyopathy|Heart Failure
Interventions: DRUG: Empagliflozin 10 MG|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Research Study of How NNC0174-0833 Behaves in Chinese Volunteers Who Are Normal Weight, Overweight or With Obesity
Status: COMPLETED
Conditions: Overweight and Obesity
Interventions: DRUG: NNC0174 0833
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Education of Medical Staff to Post Acute Covid susTained sYmptoms
Status: NOT_YET_RECRUITING
Conditions: Post-acute COVID-19 Syndrome
Interventions: OTHER: Training in the management of functional disorders|OTHER: Reimbursement of 3 long consultations
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: An Outcome Analysis for Stereotactic Body Radiation Therapy (SBRT) Treatment of Non-Small Lung Cancer Patients Using 4D PET/CT With Real-Time Position Management (RPM™) System and a Concomitant Evaluation of the Impact and Performance Characteristics of the Immobilization System
Status: TERMINATED
Conditions: Non Small Cell Lung Cancer|4D CT
Interventions: RADIATION: Stereotactic Radiosurgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Virtual Environment With Biofeedback to Promote Awareness of Relapse Risk Among Chemically Dependent Individuals
Status: COMPLETED
Conditions: Anxiety
Interventions: DEVICE: Heart and respiratory rate and VE|DEVICE: Heart and respiratory rate and video
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Twelve Week Clinical Study to Evaluate the Efficacy and Tolerability of a Sunscreen Moisturizer SPF 50+
Status: COMPLETED
Conditions: Anti-aging|Photoaging
Interventions: OTHER: Sunscreen Moisturizer|OTHER: Gentle Cleansing Lotion|OTHER: Facial Moisturizer
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized MRI-Guided Prostate Boosts Via Initial Lattice Stereotactic vs Daily Moderately Hypofractionated Radiotherapy
Status: RECRUITING
Conditions: Prostate Cancer
Interventions: RADIATION: LEAD RT|RADIATION: HEIGHT RT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of HIPEC in the Treatment of Advanced-Stage Epithelial Ovarian Cancer After Cytoreductive Surgery
Status: UNKNOWN
Conditions: Epithelial Ovarian Cancer|Fallopian Tube Cancer|Primary Peritoneal Carcinoma
Interventions: PROCEDURE: Hyperthermic Intraperitoneal Chemotherapy|PROCEDURE: cytoreductive surgery|DRUG: adjuvant chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Postoperative Effects of Preoperative Anxiety
Status: COMPLETED
Conditions: Anxiety|Pain, Postoperative
Interventions: DIAGNOSTIC_TEST: Spielberger's State-Trait Anxiety Inventory|OTHER: Visual analog scale, Ramsay's sedation scale|DRUG: Tramadol, paracetamol, diclofenac sodium
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety Study Of Chemotherapy Combined With Dendritic Cell Vaccine to Treat Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: BIOLOGICAL: LA TNBC: DC vaccine+Preop chemo|BIOLOGICAL: ER+/HER2-BC:DC vaccine+Preop chemo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Gut Microbiota in Stress, Mood and Eating Behaviours.
Status: UNKNOWN
Conditions: Eating Behavior|Stress|Mood
Interventions: DIETARY_SUPPLEMENT: Prebiotic|DIETARY_SUPPLEMENT: Maltodextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Sevoflurane as an Anesthetic During Dilation and Evacuation Procedures
Status: COMPLETED
Conditions: Blood Loss|Anesthesia
Interventions: DRUG: Sevoflurane|OTHER: No Sevoflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Lamotrigine 2 x 25 mg IR Tablets of Torrent Pharmaceuticals Pvt., Ltd., India and Lamictal ® (Lamotrigine) 2 x 25 mg Tablets of Glaxo-SmithKline, USA, in Healthy Human Adult Subjects, Under Fed Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Lamotrigine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose:
Clinical trial: Test of Long-Term Safety and Efficacy of Sirolimus-Permanent-Polymer Eluting Stent (Cypher)- and Sirolimus-Polymer-free Eluting Stents (PPS/PFS) Assessed by Optical Coherence Tomography
Status: UNKNOWN
Conditions: Coronary Heart Disease
Interventions: DEVICE: Sirolimus-Permanent-Polymer Eluting Stent|DEVICE: Sirolimus-Polymer-free Eluting Stent
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Everolimus as Maintenance Therapy for Metastatic NEC With Pulmonary or Gastroenteropancreatic Origin
Status: ACTIVE_NOT_RECRUITING
Conditions: Neuroendocrine Carcinoma
Interventions: DRUG: Everolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose Dense Re-challenge of High Dose Methotrexate With Glucarpidase for Relapsed Primary Central Nervous System Lymphoma
Status: RECRUITING
Conditions: Primary Central Nervous System Lymphoma
Interventions: DRUG: Glucarpidase|DRUG: Methotrexate (MTX)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gastrointestinal Tract Recovery in Patients Undergoing Open Ventral Hernia Repair
Status: TERMINATED
Conditions: Ventral Hernia
Interventions: DRUG: Alvimopan|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Low-Intensity Blood Flow Restriction Training as a Pre-Operative Rehabilitative Modality to Improve Post-Operative Outcomes for ACL Reconstruction
Status: COMPLETED
Conditions: ACL Injury
Interventions: BEHAVIORAL: Exercise Blood Flow Restriction training|BEHAVIORAL: SHAM Exercise Blood Flow Restriction training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of the FIFA11+ Warm-up Program on Speed, Agility, and Vertical Jump Performance in Adult Female Amateur Soccer Players
Status: COMPLETED
Conditions: Soccer|Exercise|Athletic Performance
Interventions: OTHER: FIFA11+|OTHER: 'Usual' Soccer Warm-up
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Adult Study to Evaluate Placement of Tympanostomy Tubes In-office (ADEPT)
Status: COMPLETED
Conditions: Barotrauma;Ear|OME - Otitis Media With Effusion|AOM - Acute Otitis Media|Eustachian Tube Dysfunction
Interventions: COMBINATION_PRODUCT: Tymbion Iontophoresis and Tube Delivery System (TDS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Segmental Stabilization on the Anticipatory Postural Adjustment of Subjects With Lumbar Pain
Status: COMPLETED
Conditions: Lumbar Pain
Interventions: OTHER: Segmental Stabilization Exercises|OTHER: Home Exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Chemotherapy With Nab-paclitaxel Plus Cisplatin and Capecitabine for Locally Advanced Thoracic Esophageal Squamous Cell Carcinoma
Status: UNKNOWN
Conditions: Esophageal Squamous Cell Carcinoma
Interventions: DRUG: nab-paclitaxel|DRUG: Cisplatin|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Biomarker Identification in Orthopaedic & Oral Maxillofacial Surgery Subjects to Identify Risks of Bisphosphonate Use
Status: COMPLETED
Conditions: Osteoporosis, With or Without Treatment|Bisphosphonate Treatment|Atypical Femur Fracture|Bisphosphonate Related Osteonecrosis of the Jaws (BRONJ)|Healthy Volunteers
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p