pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: The Impact of Botulinum Toxin on Brow Height and Morphology: A Randomized Controlled Trial
Status: UNKNOWN
Conditions: Brow Lifting
Interventions: DRUG: Dysport|PROCEDURE: lateral orbicularis injection|PROCEDURE: Lateral orbicularis + corrugator injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dynamic Contrast Enhanced Ultrasound for Predict and Assess Rectal Cancer Response After Neo-adjuvant Chemoradiation - RECT
Status: COMPLETED
Conditions: Rectal Cancer
Interventions: PROCEDURE: Dynamic contrast enhanced ultrasound (D-CEUS) with Sonovue® administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Effect of Medication Timing on Anticoagulation Stability in Users of Warfarin: The "INRange" RCT
Status: COMPLETED
Conditions: Atrial Fibrillation|Thrombus Due to Heart Valve Prosthesis|Deep Venous Thrombosis|Thromboembolism|DVT
Interventions: DRUG: Warfarin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The No One Waits Study: Acceptability and Feasibility of Community-based Point-of-diagnosis HCV Treatment Study
Status: COMPLETED
Conditions: Hepatitis C, Chronic
Interventions: DRUG: Epclusa (SOF/VEL)|DRUG: Standard of care|DEVICE: Fibroscan® 430 Mini Plus
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fixed Dose Heparin Study
Status: COMPLETED
Conditions: Venous Thromboembolism|Deep Vein Thrombosis|Pulmonary Embolism
Interventions: DRUG: UFH 250 U/kg or LMWH 100 U/kg sc twice daily
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Transform Type 2 Diabetes Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Type2diabetes
Interventions: OTHER: Total diet replacement|OTHER: Low-carbohydrate diet|OTHER: Intermittent fasting 5:2
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Pharmacokinetics, and Clinical Activity of LP-284 in Adult Patients With Relapsed or Refractory Lymphomas and Solid Tumors
Status: RECRUITING
Conditions: Relapsed or Refractory Lymphomas|Advanced Solid Tumor
Interventions: DRUG: LP-284
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Brief Digital CBT for Mood and Anxiety Symptoms in Acute Psychiatric Inpatients
Status: COMPLETED
Conditions: Anxiety|Depressive Symptoms|Distress, Emotional|Anxiety and Fear|Anxiety State|Mental Disorders, Severe|Psychiatric Hospitalization
Interventions: DEVICE: Mindshift CBT|DEVICE: Treatment as Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Determine the Effects of Pre-warming on OR Patient Temperatures and Surgical Outcomes
Status: COMPLETED
Conditions: Hypothermia
Interventions: DEVICE: Bair Paws Patient Adjustable Warming System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effects of Supplementing Tyrosine on Blood Pressure in Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DIETARY_SUPPLEMENT: Tyrosine|OTHER: Placebo Comparator:Sugar Pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Safety and Pharmacokinetics of Single Ascending Subcutaneous and Intravenous Doses of DS-2325a in Healthy Subjects
Status: COMPLETED
Conditions: Netherton Syndrome
Interventions: DRUG: DS-2325a|DRUG: DS-2325a|DRUG: Placebo|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Study of a Genetically Modified Adenovirus in Ovarian Cancer Patients
Status: COMPLETED
Conditions: Ovarian Cancer|Primary Peritoneal Cancer
Interventions: PROCEDURE: Tenckhoff Catheter placement|DRUG: Ad5-delta24RGD
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mass Balance Recovery and Metabolic Profile of 14C Debio 1450 Following Single Oral and Intravenous Doses in Healthy Male Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: [14C-pos 1]-Debio 1450 BES Solution|DRUG: [14C-pos 25]-Debio 1450 BES Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Ultrasound-Guided Adductor Canal Block for Total Knee Arthroplasty Surgery
Status: RECRUITING
Conditions: Knee Disease|Knee Deformity|Knee Pain Chronic|Knee Arthropathy|Knee Osteoarthritis
Interventions: DRUG: 20 ml volume adductor canal block|DRUG: 30 ml volume adductor canal block|DRUG: 40 ml volume adductor canal block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Recycling of Three Pressable Ceramics With Different Weight Percentage
Status: ACTIVE_NOT_RECRUITING
Conditions: Plaque|Patient Satisfaction|Caries, Cervical|Post Operative Pain
Interventions: OTHER: clinical measurements and evaluation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of The Effectiveness of m-DAKBAS on Foot Care
Status: COMPLETED
Conditions: Diabetic Foot|Foot Ulcer, Diabetic|Health Knowledge, Attitudes, Practice
Interventions: OTHER: knowledge, behaviour, self efficacy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Mobilization and Mobilization With Movement Effect on Sub Acromial Space in Impingement Syndrome.
Status: COMPLETED
Conditions: Impingement Syndrome
Interventions: OTHER: Mobilization|OTHER: Mobilization with movement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: PTM202 and Modulation of Host Resistance to Diarrheagenic E. Coli
Status: COMPLETED
Conditions: Traveler's Diarrhea
Interventions: BIOLOGICAL: E. coli strain E1392-75-2A|DEVICE: PTM202
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pegylated Interferon Alfa-2a Maintenance Therapy and Liver Disease Progression in People Infected With Both HIV and Hepatitis C Virus (HCV)
Status: COMPLETED
Conditions: HIV Infections|Hepatitis C|Liver Disease
Interventions: DRUG: Peginterferon alfa-2a|DRUG: Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Study of Pracinostat With Azacitidine in Patients With Previously Untreated Myelodysplastic Syndrome
Status: COMPLETED
Conditions: Myelodysplastic Syndrome
Interventions: DRUG: pracinostat|DRUG: Placebo|DRUG: Azacitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Innovative Anti-pneumococcal Vaccine Strategies in Patients With ANCA-associated Vasculitis Receiving Rituximab Therapy
Status: COMPLETED
Conditions: Invasive Pneumococcal Infection
Interventions: BIOLOGICAL: PCV13|BIOLOGICAL: PPV23|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of an Automated Insulin Delivery System in Adult Participants With Type 1 Diabetes
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus
Interventions: DEVICE: AID System|DRUG: Insulin Lispro
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: A Study to Evaluate Tolerability and Efficacy of Evolocumab (AMG 145) in Japanese Subjects
Status: COMPLETED
Conditions: Hypercholesterolemia and High Risk for Cardiovascular Events
Interventions: BIOLOGICAL: Evolocumab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study on the Correlation Between Neurotrophic Factors and the Condition of Stroke Patients
Status: RECRUITING
Conditions: Stroke
Interventions: PROCEDURE: acupuncture|BEHAVIORAL: computerized cognitive training system|BEHAVIORAL: aerobic exercise|BEHAVIORAL: tranditional cognitive training|OTHER: Conventional treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Continuously Infused Recombinant-Methionyl Human Glial Cell Line-Derived Neurotrophic Factor (GDNF) to Treat Progressive Supranuclear Palsy
Status: COMPLETED
Conditions: Progressive Supranuclear Palsy
Interventions: DRUG: GDNF & Synchro Med Infusion System
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Empagliflozin and Renal Oxygenation in Healthy Volunteers
Status: COMPLETED
Conditions: Nephropathy
Interventions: DRUG: Empagliflozin 10 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study to Learn if 200mg Test Drug (Fostamatinib) Helps People With Large B-Cell Lymphoma,a Type of Blood Cancer
Status: COMPLETED
Conditions: Diffuse Large B-Cell Lymphoma
Interventions: DRUG: Fostamatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bevacizumab, Capecitabine, and Oxaliplatin in Treating Advanced Small Intestinal or Ampulla of Vater Adenocarcinoma
Status: COMPLETED
Conditions: Ampulla of Vater Adenocarcinoma|Small Intestinal Adenocarcinoma|Stage III Ampulla of Vater Cancer AJCC v8|Stage III Small Intestinal Adenocarcinoma AJCC v8|Stage IIIA Ampulla of Vater Cancer AJCC v8|Stage IIIA Small Intestinal Adenocarcinoma AJCC v8|Stage IIIB Ampulla of Vater Cancer AJCC v8|Stage IIIB Small Intestinal Adenocarcinoma AJCC v8|Stage IV Ampulla of Vater Cancer AJCC v8|Stage IV Small Intestinal Adenocarcinoma AJCC v8
Interventions: BIOLOGICAL: Bevacizumab|DRUG: Capecitabine|DRUG: Oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Does Biological Sex Influence Insulin Sensitivity and Muscle Metabolism Following High-intensity Interval Exercise?
Status: RECRUITING
Conditions: Exercise
Interventions: OTHER: Seated Rest (Non-exercise control)|OTHER: High-intensity interval exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Combination of Methotrexate and Phototherapy Versus Phototherapy in Adults With Progressive Vitiligo
Status: RECRUITING
Conditions: Vitiligo
Interventions: DRUG: Methotrexate|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Clinical Efficacy of Whole Body Cryotherapy in the Cryosense Cabin for the Treatment of Fibromyalgia
Status: COMPLETED
Conditions: Fibromyalgia
Interventions: DEVICE: Whole body cryotherapy sessions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Paradoxical Excitement Response During Sedation Between Dexmedetomidine and Propofol in Hazardous Alcohol Drinker
Status: UNKNOWN
Conditions: Anesthesia, Spinal|Sedation, Conscious|Dexmedetomidine|Alcohol Drinking|Anesthesia, Epidural|Propofol
Interventions: DRUG: Dexmedetomidine|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Phase 1 Study of KH607 Tablets
Status: RECRUITING
Conditions: Healthy
Interventions: DRUG: 2mg KH607 tablets|DRUG: 5mg KH607 tablets|DRUG: 10mg KH607 tablets|DRUG: 20mg KH607 tablets|DRUG: 30mg KH607 tablets|DRUG: 40mg KH607 tablets|DRUG: 50mg KH607 tablets|DRUG: 60mg KH607 tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: T-PEMF Headband Stimulation for Patients With Moderate to Servere Depression
Status: RECRUITING
Conditions: Moderate Depression|Severe Depressive Episode Without Psychotic Symptoms|Recurrent Depressive Disorder, Current Episode Moderate|Recurrent Depressive Disorder, Current Episode Severe Without Psychotic Symptoms
Interventions: DEVICE: Treatment with MoodHeadBand (T-PEMF treatment)|DEVICE: Inactive treatment with MoodHeadBand (Placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomised Single Centre Study to Compare the Long-term Performance of Acryloc™ and Palacos® R Bone Cements in Primary Total Hip Replacement
Status: TERMINATED
Conditions: Osteoarthritis|Post-traumatic Arthritis|Avascular Necrosis
Interventions: DEVICE: Acryloc™ GHV|DEVICE: Palacos R
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Robotic-Assisted Surgery in Treating Patients With Spine Tumors
Status: WITHDRAWN
Conditions: Adult Spinal Cord Neoplasm|Spinal Bone Metastases|Spinal Cord Metastases
Interventions: PROCEDURE: therapeutic conventional surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Study of Albendazole in Patients With Epilepsy Due to Neurocysticercosis
Status: COMPLETED
Conditions: Epilepsy|Cysticercosis
Interventions: DRUG: albendazole|DRUG: dexamethasone|DRUG: phenytoin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Balance: A Pragmatic Trial of a Digital Health Intervention to Prevent Weight Gain in Primary Care
Status: COMPLETED
Conditions: Obesity|Overweight|Overnutrition|Nutrition Disorders|Signs and Symptoms
Interventions: BEHAVIORAL: Intervention Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Cannabidiol (CBD) on Vision and Driving
Status: ACTIVE_NOT_RECRUITING
Conditions: Cannabis Use
Interventions: OTHER: Placebo (CBD 0%)|OTHER: CBD 15%|OTHER: CBD 30%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Diabetic Macular Edema: Relevance of Staging Progression on Therapeutic Outcome
Status: COMPLETED
Conditions: Diabetic Macular Edema
Interventions: DRUG: intravitreal administration of bevacizumab/ranibizumab/aflibercept/desamethazone
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Immunogenicity of Intradermal Versus Subcutaneous Doses of Menomune®
Status: COMPLETED
Conditions: Meningococcal Infections|Meningitis
Interventions: BIOLOGICAL: Meningococcal Polysaccharide Groups A\C\Y\W-135 Combined|BIOLOGICAL: Meningococcal Polysaccharide Groups A\C\Y\W-135 Combined|BIOLOGICAL: Meningococcal Polysaccharide Groups A\C\Y\W-135 Combined|BIOLOGICAL: Meningococcal Polysaccharide Groups A\C\Y\W-135 Combined|BIOLOGICAL: Meningococcal Polysaccharide Groups A\C\Y\W-135 Combined
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Efficacy and Safety of JS002 in Patients With Heterozygous Familial Hypercholesterolemia (HeFH).
Status: COMPLETED
Conditions: Heterozygous Familial Hypercholesterolemia
Interventions: BIOLOGICAL: Ongericimab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Computed Tomography Scan Versus Color Duplex Ultrasound for Surveillance of Endovascular Repair of Abdominal Aortic Aneurysm. A Prospective Multicenter Study
Status: COMPLETED
Conditions: Endovascular Repair of Abdominal Aortic Aneurysm
Interventions: PROCEDURE: Computed tomography scan versus color duplex ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Mulligan Concept in the Treatment of Ankle Sprains
Status: COMPLETED
Conditions: Ankle Sprain 1St Degree|Ankle Sprain 2Nd Degree
Interventions: PROCEDURE: Mulligan concept|PROCEDURE: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Interleukin-1 Trap to Treat Vascular Dysfunction in Chronic Kidney Disease (CKD)
Status: COMPLETED
Conditions: Renal Insufficiency, Chronic
Interventions: DRUG: Rilonacept|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: To Evaluate the Therapeutic Equivalence and Safety of Azelaic Acid 15% Topical Gel
Status: COMPLETED
Conditions: Rosacea
Interventions: DRUG: Azelaic Acid 15% topical gel|DRUG: Finacea® (azelaic acid) Gel, 15%|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Preventing Health Damaging Behaviors in Male and Female Army Recruits
Status: TERMINATED
Conditions: Sexually Transmitted Infection (STI) Prevention|Unintended Pregnancy Prevention|Sexual Risk Reduction|Alcohol and Other Substance Use Prevention|Intimate Partner Violence Prevention
Interventions: BEHAVIORAL: Preventing Helath Damaging Health Behaviors in Male and Female Army Recruits
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Theta Burst Stimulation for Headaches After Traumatic Brain Injury
Status: UNKNOWN
Conditions: Post-Traumatic Headache|Transcranial Magnetic Stimulation|Brain Injuries, Traumatic|Quality of Life
Interventions: DEVICE: Theta Burst Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: STA-9090 in Castration-Resistant Prostate Cancer With Assessment of Androgen Receptor Pathway Signaling
Status: WITHDRAWN
Conditions: Adenocarcinoma of the Prostate
Interventions: DRUG: STA9090|DRUG: STA9090 with Dutasteride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Influence of tDCS on the Arm and Hand Function in Stroke Patients
Status: COMPLETED
Conditions: Transcranial Direct Current Stimulation|Cerebrovascular Accident (CVA)
Interventions: DEVICE: transcranial direct current stimulation (tDCS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Non-Insulin Dependent Diabetes Mellitus (NIDDM) and Angiotensin Converting Enzyme 2 (ACE2): Diabetic Patients Treated With Antihypertensive Drugs
Status: UNKNOWN
Conditions: NIDDM
Interventions: DRUG: candesartan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: ECT
Clinical trial: Trial of Paclitaxel/Bevacizumab +/- Everolimus for Patients With HER2-Negative Metastatic Breast Cancer
Status: COMPLETED
Conditions: Metastatic Breast Cancer
Interventions: DRUG: Everolimus|DRUG: Bevacizumab|DRUG: Paclitaxel|DRUG: Placebo|DRUG: Bevacizumab|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Minimally Invasive Surgery Techniques for One-level Degenerative Lumbar Deformities Correction
Status: WITHDRAWN
Conditions: Intervertebral Disc Degeneration|Spinal Fusion
Interventions: PROCEDURE: Minimally invasive one-level lumbar deformity correction
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single Dose Steroid Before Thyroidectomy for Benign Disease to Improve Postoperative Nausea, Pain, and Vocal Function
Status: UNKNOWN
Conditions: Postoperative Pain|Postoperative Nausea and Vomit|Postoperative Vocal Function|Thyroidectomy
Interventions: DRUG: Dexamethasone|DRUG: saline solution|PROCEDURE: Thyroidectomy, total or partial
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of CD123-targeted CAR-NK for Relapsed/Refractory Acute Myeloid Leukemia or Blastic Plasmacytoid Dendritic Cell Neoplasm
Status: RECRUITING
Conditions: Acute Myeloid Leukemia|Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN)|Relapse Leukemia|Refractory Leukemia
Interventions: BIOLOGICAL: CD123 targeted CAR-NK cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Functional Recovery From Facial Paralysis
Status: RECRUITING
Conditions: Peripheral Facial Paralysis|Facial Palsy|Synkineses
Interventions: OTHER: Selective muscle electrostimulation with exponential current|OTHER: Facial muscle reeducation in front of the mirror
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acceptability Study on Nutricomp® Drink Plus Fibre in Adults
Status: COMPLETED
Conditions: Adult Patients in Need of High-energy Oral Nutritional Supplementation
Interventions: DIETARY_SUPPLEMENT: Nutricomp Drink Plus Fibre
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study to Evaluate Two Doses of Oral DMI-5207 in Adult Subjects With Diabetic Macular Edema
Status: COMPLETED
Conditions: Diabetic Macular Edema
Interventions: DRUG: Danazol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics of Flibanserin in Postmenopausal Women With Hypoactive Sexual Desire Disorder (HSDD)
Status: COMPLETED
Conditions: Sexual Dysfunctions, Psychological
Interventions: DRUG: flibanserin 100 mg dose every evening
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Interest of the Nitrous Oxide During Intravesical Injection of Botulinum Toxin A
Status: COMPLETED
Conditions: Injection Site Vesicles
Interventions: DRUG: Nitrous Oxide|DRUG: Oxygen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: MOCHA Moving Forward: a CBPR Investigation of Chronic Disease Prevention in Older, Low-income African-American Men
Status: COMPLETED
Conditions: Chronic Disease of Cardiovascular System|Multiple Chronic Conditions|Chronic Disease
Interventions: BEHAVIORAL: MOCHA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Study of the Effects of a Mineralized Water Ingestion Upon Lipidic Absorption Mechanisms
Status: COMPLETED
Conditions: Moderated Cholesterolemia
Interventions: OTHER: Mineralized water|OTHER: Low mineralized water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Study of Plozasiran (ARO-APOC3) in Adults With Severe Hypertriglyceridemia
Status: RECRUITING
Conditions: Severe Hypertriglyceridemia
Interventions: DRUG: Plozasiran Injection|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Glucose Clamp Study of Wockhardt's Recombinant Insulin Analog Glargine(Glaritus) With Lantus in T1DM
Status: COMPLETED
Conditions: Type1 Diabetes
Interventions: BIOLOGICAL: Glargine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study " COFLORES "
Status: COMPLETED
Conditions: Myocardial Perfusion
Interventions: DEVICE: Magnetic Resonance Imaging (MRI)|DEVICE: phosphorus-31 Magnetic Resonance Spectroscopy|DEVICE: sodium-23 MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 2b Trial of EPB-348 for the Treatment of Herpes Zoster
Status: COMPLETED
Conditions: Herpes Zoster
Interventions: DRUG: EPB-348|DRUG: Valacyclovir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multimodal Assesment of Alzheimer Patients
Status: NOT_YET_RECRUITING
Conditions: Mild Cognitive Impairment|Alzheimer Disease, Late Onset|Cognitive Impairment|Dementia
Interventions: DEVICE: MRI Scanning|DEVICE: 64-channel EEG|DEVICE: Polysomnography|BIOLOGICAL: Blood samples|BIOLOGICAL: Fecal samples|BEHAVIORAL: Cognitive tests
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: ACT Intervention for Type 2 Diabetes Management for Rural and Underserved Community
Status: RECRUITING
Conditions: Type 2 Diabetes
Interventions: BEHAVIORAL: Acceptance and Commitment Therapy|DEVICE: Abbott FreeStyle® Libre® 3|OTHER: Generic Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Cannabigerol on Attention-Deficit/Hyperactivity Disorder
Status: NOT_YET_RECRUITING
Conditions: Attention-Deficit/Hyperactivity Disorder
Interventions: DIETARY_SUPPLEMENT: Cannabigerol|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Epidermal Skin Grafts to Improve Healing In Radiation Wounds
Status: RECRUITING
Conditions: Radiation Dermatitis
Interventions: DEVICE: CelluTomeTM Epidermal Harvesting System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective Evaluation of the Prognostic Impact of Measurable Residual Disease (MRD) Within a Phase III Study Comparing a Fixed Duration Therapy Versus Continuous Therapy With Daratumumab, Lenalidomide, and Dexamethasone for Relapsed Multiple Myeloma Requiring a First Salvage Treatment.
Status: RECRUITING
Conditions: Multiple Myeloma
Interventions: OTHER: Assessment of MRD
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Prospective Surveillance For Respiratory Virus Infections In Children Undergoing Hematopoietic Stem Cell Transplantation
Status: COMPLETED
Conditions: Respiratory Virus Infections
Interventions: OTHER: Nasopharyngeal Washes|OTHER: Fluorescent antibody detection|OTHER: Respiratory viral culture
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Evaluate the Safety and Efficacy of Ublituximab in Combination With Umbralisib for Participants Previously Enrolled in Protocol UTX-TGR-304
Status: TERMINATED
Conditions: Chronic Lymphocytic Leukemia
Interventions: BIOLOGICAL: Ublituximab|DRUG: Umbralisib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Caffeine Supplementation, Resistance Training and Blood Antioxidant Status
Status: COMPLETED
Conditions: Caffeine
Interventions: DIETARY_SUPPLEMENT: Caffeine supplementation|DIETARY_SUPPLEMENT: Placebo treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nasr Fascial Closure: A Novel Device for Fascial Closure in Laparoscopic Surgery
Status: RECRUITING
Conditions: Cholecystolithiasis
Interventions: DEVICE: Nasr fascial closure device|DEVICE: Berci Fascial Closure Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Polymorphisms in the Human Matrix Metalloproteinase Genes MMP1, MMP3, and MMP9: Genetic Risk Factors of Primary Open Angle Glaucoma?
Status: COMPLETED
Conditions: Glaucoma
Interventions: PROCEDURE: Blood Sample
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Persistent Low Back and Pelvic Pain 3-6 Months Post Partum
Status: COMPLETED
Conditions: Pelvic Girdle Pain Post Partum|Low Back Pain Post Partum
Interventions: OTHER: exercise advise|OTHER: chiropractic treatment and exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 3 Efficacy & Safety of SB206 & Vehicle Gel for the Treatment of MC
Status: COMPLETED
Conditions: Molluscum Contagiosum
Interventions: DRUG: SB206 12%|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study Of Single Ascending And Multiple Doses Of PF-04447943 In Japanese Subjects.
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: PF-04447943|DRUG: PF-04447943|DRUG: PF-04447943|DRUG: Placebo|DRUG: PF-04447943|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation and Optimization of PB127 Myocardial Perfusion Echocardiography on Ultrasound Systems
Status: TERMINATED
Conditions: Coronary Artery Disease|Healthy
Interventions: DRUG: PB127 for Injectable Suspension
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Clinical Study of T3011 in Combination With Toripalimab and Regorafenib in Patients With Colorectal Cancer
Status: NOT_YET_RECRUITING
Conditions: Colorectal Cancer Metastatic
Interventions: BIOLOGICAL: T3011 hepatic artery infusion|DRUG: toripalimab|DRUG: regorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of the Hippotherapy Simulator in Children and Adolescents With Cystic Fibrosis
Status: COMPLETED
Conditions: Cystic Fibrosis in Children
Interventions: OTHER: Exercise with hippotherapy simulator|OTHER: Respiratory Physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hearing Aid Performance Study for Different Spatial Configurations
Status: COMPLETED
Conditions: Hearing Loss
Interventions: OTHER: Beamformer Benefit: Speech intelligibility and Listening effort|OTHER: Speech Enhancer benefit: Speech intelligibility, Listening effort and Subjective Speech intelligibility|OTHER: Hearing aid benefit: Speech intelligibility in noise (unaided vs aided condition)|OTHER: Hearing aid benefit: Speech intelligibility in noise (aided condition)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Neuromodulating Cortical Regions Involved in Neurogenic Bladder in MS
Status: RECRUITING
Conditions: Neurogenic Bladder|Multiple Sclerosis|Overactive Bladder
Interventions: DEVICE: Magstim Rapid2 System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Surveillance for Malignant Transformation of Neurofibromatosis Type 1 (NF1) Related Peripheral Nerve Sheath Tumors (PNST)
Status: NOT_YET_RECRUITING
Conditions: Neurofibromatosis 1|Nerve Sheath Neoplasms
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Contributions to Hypertension With Androgen Deprivation Therapy
Status: RECRUITING
Conditions: Androgen Deprivation Therapy|Prostate Cancer|Hypertension|Autonomic Dysfunction|Renal Disease
Interventions: DRUG: Gonadotropin Releasing Hormone Agonists (GNRH)|DRUG: Androgen receptor (AR) inhibitor|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Is Botox Effective in Relieving Pain From Knee Osteoarthritis?
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: DRUG: Botulinum toxin type A (Btx-A)|DRUG: Cortisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cyclophosphamide With Biochemical Progression During Lenalidomide-Dexamethasone Treatment for Relapsed/Refractory Multiple Myeloma (MM)
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Cyclophosphamide|DRUG: Lenalidomide|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Mesna to Prevent Doxorubicin-induced Plasma Protein Oxidation and Tumor Necrosis Factor Alpha (TNF-α) Release
Status: COMPLETED
Conditions: Breast Cancer|Non-Hodgkin's Lymphoma
Interventions: DRUG: Mesna|DRUG: Saline|DRUG: Doxorubicin|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Subcutaneous Administration of Fremanezumab (TEV-48125) for the Preventive Treatment of Migraine
Status: COMPLETED
Conditions: Migraine
Interventions: DRUG: Fremanezumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Proton or Photon RT for Retroperitoneal Sarcomas
Status: RECRUITING
Conditions: Retroperitoneal Sarcoma
Interventions: RADIATION: IG-IMPT|RADIATION: IG IMRT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Global Study Comparing a rivAroxaban-based Antithrombotic Strategy to an antipLatelet-based Strategy After Transcatheter aortIc vaLve rEplacement to Optimize Clinical Outcomes
Status: TERMINATED
Conditions: Transcatheter Aortic Valve Replacement
Interventions: DRUG: Rivaroxaban (Xarelto, BAY59-7939)|DRUG: Acetylsalicylic Acid (ASA)|DRUG: Clopidogrel|DRUG: Rivaroxaban (Xarelto, BAY59-7939)|DRUG: Vitamin K antagonist (VKA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Bortezomib in Intrahepatic Cholangiocellular Carcinoma
Status: UNKNOWN
Conditions: Intrahepatic Cholangiocarcinoma
Interventions: DRUG: Bortezomib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Renal Denervation in Patients With Heart Failure Secondary to Chagas Disease
Status: UNKNOWN
Conditions: Heart Failure|Heart Failure, Systolic|Chagas Disease|Chagas Cardiomyopathy
Interventions: DEVICE: transcatheter renal denervation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects Magnesium Sulfate and Labetalol Infusion on Peripheral Perfusion and Pain in Nasal Surgeries
Status: COMPLETED
Conditions: Peripheral Perfusion|Postoperative Pain
Interventions: DRUG: Magnesium Sulfate Injection|DRUG: Labetalol Injectable Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Safety Study to Investigate the Skin Sensitization Potential of MFC51123
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Diclofenac + Menthol Gel|DRUG: Diclofenac Only Gel|DRUG: Menthol Only Gel|DRUG: Placebo Only Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: High Potency Statins and the Risk of Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Cardiovascular Disease
Interventions: DRUG: Rosuvastatin (≥10 mg)|DRUG: Atorvastatin (≥20 mg)|DRUG: Simvastatin (≥40 mg)|DRUG: Fluvastatin|DRUG: Pravastatin|DRUG: Lovastatin|DRUG: Rosuvastatin (<10mg)|DRUG: Atorvastatin (<20mg)|DRUG: Simvastatin (<40 mg)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Percutaneous Peripheral Nerve Stimulation (Neuromodulation) for Postoperative Analgesia
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DEVICE: Percutaneous peripheral nerve stimulation|DEVICE: Sham stimulation|DEVICE: Percutaneous peripheral nerve stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Autograft Versus Calcium Phosphate Macroporous Bioceramics as Bone Substitute for Tibial Valgus Osteotomy
Status: UNKNOWN
Conditions: Osteoarthritis of the Knee
Interventions: DEVICE: calcium phosphate macroporous bioceramics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Chewing Gum and WeChat Enhanced Instructions on the Bowel Preparation Quality in Patients With Constipation
Status: COMPLETED
Conditions: Colonoscopy|Colonic Polyp|Constipation
Interventions: OTHER: Chewing gum combined with WeChat enhanced instructions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of Immunization Schedules of Inactivated Hepatitis A Vaccine and Combined Hepatitis A and Hepatitis B Vaccine
Status: COMPLETED
Conditions: Hepatitis A|Hepatitis B
Interventions: BIOLOGICAL: Inactivated Hepatitis A vaccine (HAV)|BIOLOGICAL: Combined hepatitis A and hepatitis B vaccine (HABV)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: TWO DİFFERENT ELECTROSURGERY DEVICES AS MONOPOLAR HOOC AND PLASMAKINETIC BIPOLAR SPATULA EFFECTIVENESS DURING COLPOTOMY
Status: UNKNOWN
Conditions: Uterine Fibroid|Ovary Cyst|Endometrial Hyperplasia|Cervical Dysplasia
Interventions: DEVICE: MONOPOLAR HOOC|DEVICE: PLASMAKINETIC BIPOLAR SPATULA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Lcr35 / ICU / P. Aeruginosa
Status: TERMINATED
Conditions: Pseudomonas Infections
Interventions: DRUG: Probiotic Lactobacillus casei rhamnosus (Lcr35)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Antimicrobial Resistant Organism Decolonization After Microbiome Perturbation
Status: NOT_YET_RECRUITING
Conditions: Gram-negative Bacteremia|Microbial Colonization|Antibiotic Resistant Infection
Interventions: DRUG: MET-2|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intravenous Zoledronic Acid for the Treatment of Osteoporosis and Osteonecrosis in Children With Leukemia: A Pilot Study
Status: WITHDRAWN
Conditions: Osteoporosis|Osteonecrosis|Acute Lymphoblastic Leukemia
Interventions: DRUG: Zoledronic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hypobaric Spinal or Hyperbaric in Partial Hip Arthroplasty
Status: RECRUITING
Conditions: Post Operative Pain
Interventions: PROCEDURE: spinal anesthesia with hyberbaric bupivacaine|PROCEDURE: spinal anesthesia with hypobaric bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Induction Chemotherapy Using Doxorubicin and Cisplatin Followed by Combretastatin A4 Phosphate and Radiation Therapy in Treating Patients With Newly Diagnosed Regionally Advanced Anaplastic Thyroid Cancer
Status: TERMINATED
Conditions: Head and Neck Cancer
Interventions: BIOLOGICAL: filgrastim|BIOLOGICAL: pegfilgrastim|DRUG: cisplatin|DRUG: doxorubicin hydrochloride|DRUG: fosbretabulin disodium|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Safety and Tolerability of Brexpiprazole in the Treatment of Adults With Borderline Personality Disorder (BPD)
Status: COMPLETED
Conditions: Borderline Personality Disorder
Interventions: DRUG: Brexpiprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Trial of Topotecan With M6620, an ATR Kinase Inhibitor, in Small Cell Lung Cancers and Small Cell Cancers Outside of the Lungs
Status: ACTIVE_NOT_RECRUITING
Conditions: Bladder Small Cell Neuroendocrine Carcinoma|Extensive Stage Lung Small Cell Carcinoma|Extrapulmonary Small Cell Neuroendocrine Carcinoma|Limited Stage Lung Small Cell Carcinoma|Platinum-Resistant Lung Small Cell Carcinoma|Platinum-Sensitive Lung Small Cell Carcinoma|Prostate Small Cell Neuroendocrine Carcinoma|Recurrent Lung Small Cell Carcinoma
Interventions: DRUG: Berzosertib|PROCEDURE: Biopsy|PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|DRUG: Topotecan Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Botulinum Toxin A for Shoulder Pain After Stroke
Status: UNKNOWN
Conditions: Stroke|Pain
Interventions: DRUG: Botulinum toxin A|DRUG: Triamcinolone Acetonide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cisplatin, Pemetrexed and Bevacizumab for Untreated Malignant Mesothelioma
Status: COMPLETED
Conditions: Mesothelioma
Interventions: DRUG: bevacizumab|DRUG: cisplatin|DRUG: pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Pioglitazone and Fortamet Combination Therapy in Subjects With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: DRUG: Pioglitazone and metformin|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Targeted Radiotherapy in Androgen-suppressed Prostate Cancer Patients.
Status: UNKNOWN
Conditions: Prostate Cancer|Metastasis|Toxicity Due to Radiotherapy|Circulating Tumour DNA
Interventions: RADIATION: SBRT + ADT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase III Trial to Evaluate the Efficacy and Safety of LC15-0444 Compared With Sitagliptin Added to Ongoing Metformin Therapy in Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: LC15-0444 25mg bid|DRUG: LC15-0444 50mg qd|DRUG: Sitagliptin 100mg qd
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: To Evaluate the Safety and Efficacy for GORE TAG Thoracic Endoprosthesis in the Treatment of Thoracic Aortic Disease
Status: COMPLETED
Conditions: Aneurysm, Dissecting|Aortic Aneurysm, Thoracic
Interventions: DEVICE: Endovascular Stent-graft repair of descending thoracic aorta
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Studying Gene Expression in Tissue Samples From Young Patients With Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Leukemia
Interventions: GENETIC: RNA analysis|GENETIC: gene expression analysis|GENETIC: reverse transcriptase-polymerase chain reaction|OTHER: laboratory biomarker analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p