pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Mechanisms of Hypertension in Women With Polycystic Ovary Syndrome
Status: TERMINATED
Conditions: Polycystic Ovary Syndrome|Hypertension
Interventions: DRUG: GnRH antagonist|DRUG: GnRH antagonist + MethylTESTOSTERone 5 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Does Motivational Interviewing Improve Behavioral Weight Loss Outcomes for Obesity?
Status: COMPLETED
Conditions: Obesity|Overweight
Interventions: BEHAVIORAL: Motivational Interviewing|BEHAVIORAL: Attention Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ultrasound-guided Rectus Sheath Block for Post-operative Pain Control Following Umbilical Hernia Repair
Status: COMPLETED
Conditions: Pain
Interventions: PROCEDURE: rectus sheath block|PROCEDURE: local anesthetic infiltration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Telmisartan/Hydrochlorothiazide Treatment in Hypertensive Patients Under Real-life Setting
Status: COMPLETED
Conditions: Primary Hypertension
Interventions: DRUG: Telmisartan/hydrochlorothiazide (Pritor Plus, BAY98-7103)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Oral Enteral Nutrition in Infants With Cerebral Palsy and Dysphagia
Status: COMPLETED
Conditions: Cerebral Palsy
Interventions: BEHAVIORAL: systemic therapy|DEVICE: Intermittent Oro-Esophageal Tube Feeding|DEVICE: Persistent Nasogastric Tube Feeding
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pharmacological Study That Measures Omeprazole Effect on Aspirins Absorption in Healthy Volunteers
Status: COMPLETED
Conditions: Aspirin Blood Level|Proton Pump Inhiditor Treatment
Interventions: DRUG: aspirin and omeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Transcranial Direct Current Stimulation and Rehabilitation to Ameliorate Impairments in Neurocognition After Stroke
Status: RECRUITING
Conditions: Ischemic Stroke|Cognitive Impairment
Interventions: DEVICE: tDCS|DEVICE: sham tDCS|BEHAVIORAL: Cognitive Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Benefits of Morphine Gel for Pain Reduction in Patients With Cancer Wounds
Status: RECRUITING
Conditions: Wounds and Injuries|Cancer Pain|Cancer, Breast|Cancer Head Neck
Interventions: DRUG: Morphine Sulfate|DRUG: Lidocaine Hcl 2% Jelly
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of the Combined Use of Thiamine and Biotin in Patients With Huntington's Disease
Status: RECRUITING
Conditions: Huntington Disease
Interventions: DRUG: Moderate doses of Thiamine y Biotin|DRUG: High doses of Thiamine y Biotin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Device for Monitoring Pain During Intraoperative, Pre/Post Surgical Periods: Comparison With Standard of Care Monitoring
Status: TERMINATED
Conditions: Pain Measurement|Assessment, Pain
Interventions: OTHER: These patients receive the Baeta device and take it home
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Safety Study of BLS-M22 in Healthy Volunteers
Status: COMPLETED
Conditions: Muscular Dystrophy, Duchenne
Interventions: BIOLOGICAL: BLS-M22|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial of Ginseng in Diabetes
Status: COMPLETED
Conditions: Diabetes
Interventions: DRUG: Ginseng|DRUG: Ginseng|DRUG: ginsenoside RE|DIETARY_SUPPLEMENT: Placebo (sugar pill)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Sacral Spread of Sensory Block After Dural Puncture Epidural Technique Compared With Epidural for Labour Analgesia
Status: COMPLETED
Conditions: Labor Pain|Analgesia
Interventions: PROCEDURE: DPEA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of Intravenous Iron Preparation to Iron Deficiency Anemia
Status: COMPLETED
Conditions: Iron Deficiency Anemia
Interventions: DRUG: Z-213|DRUG: Saccharated Ferric Oxide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Can Vitamin D Supplementation in the First Year of Life Prevent Food Allergy in Infants? The VITALITY Trial: Parts 1&2
Status: ACTIVE_NOT_RECRUITING
Conditions: Food Allergy
Interventions: DRUG: Vitamin D|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Endovascular Repair of Descending ThoracoAbdominal Aortic Pathologies Using Physician Modified Endovascular Prosthesis
Status: RECRUITING
Conditions: Aortic Disease
Interventions: PROCEDURE: Exclusion of thoracoabdominal lesion|DEVICE: Endovascular Device Implant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mobile & Online-Based Interventions to Lessen Pain
Status: RECRUITING
Conditions: Chronic Pain|Opioid Misuse|Opioid Use Disorder
Interventions: BEHAVIORAL: Empowered Relief On-Demand|BEHAVIORAL: Health Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Brentuximab Vedotin in Participants With Relapsed or Refractory Systemic Anaplastic Large Cell Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Lymphoma
Interventions: DRUG: Brentuximab vedotin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Azeliragon and Chemoradiotherapy in Newly Diagnosed Glioblastoma
Status: RECRUITING
Conditions: Glioblastoma
Interventions: DRUG: Azeliragon 5 mg|DRUG: Azeliragon 10 mg|DRUG: Azeliragon 20 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pembrolizumab and Hypofractionated Stereotactic Radiotherapy in Patients With Malignant Pleural Mesothelioma
Status: TERMINATED
Conditions: Advanced Malignant Pleural Mesothelioma
Interventions: DRUG: Pembrolizumab|RADIATION: Stereotactic Body Radiotherapy (SBRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Inflammatory Status of Visceral Adipose Tissue in Obese Patients Related to Periodontitis Severity
Status: UNKNOWN
Conditions: Parodontitis|Obesity|Metabolism Disorders
Interventions: OTHER: SEVERE PERIODONTITIS|OTHER: NO PERIODONTITIS
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of South Beach Diet (SBD™) Using SBD™ Products Compared to the American Diabetic Association (ADA) Diabetes Meal Plan on Body Weight and Satiety in Diabetic Women
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: BEHAVIORAL: South Beach Diet with South Beach Diet Products|BEHAVIORAL: American Diabetes Association Diabetes Meal Plan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Methyl-qPCR : a New Predictive Marker for Epstein-Barr Virus-associated Lymphoproliferations During Allogeneic Hematopoietic Stem Cell Transplantation
Status: COMPLETED
Conditions: Epstein-Barr Viraemia|Hematologic Diseases|Allogeneic Disease
Interventions: BIOLOGICAL: biological collection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Hu8F4 in Treating Patients With Advanced Hematologic Malignancies
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome|Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive|Hematopoietic and Lymphoid Cell Neoplasm|High Risk Myelodysplastic Syndrome|Myelodysplastic Syndrome With Excess Blasts-1|Myelodysplastic Syndrome With Excess Blasts-2|Myelofibrosis|Recurrent Acute Myeloid Leukemia|Recurrent Chronic Myelomonocytic Leukemia|Refractory Chronic Myelomonocytic Leukemia|Secondary Acute Myeloid Leukemia
Interventions: DRUG: Anti-PR1/HLA-A2 Monoclonal Antibody Hu8F4|OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacological Study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Safety and Efficacy of NC-503 in Secondary (AA) Amyloidosis
Status: COMPLETED
Conditions: Secondary (AA) Amyloidosis|Rheumatoid Arthritis|Nephrotic Syndrome|Familial Mediterranean Syndrome|Kidney Diseases|Gastrointestinal Diseases
Interventions: DRUG: NC-503 (Anti-amyloidotic (AA) Agent)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Prospective Study of Ranibizumab in the Treatment of Postoperative Recurrent Vitreous Haemorrhage of Diabetic Retinopathy
Status: RECRUITING
Conditions: Diabetic Retinopathy|Postoperative Recurrent Vitreous Hemorrhage|Pars Plana Vitrectomy|Ranibizumab
Interventions: DRUG: Ranibizumab Injection|PROCEDURE: PPV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of CF101 to Treat Patients With Dry Eye Disease
Status: COMPLETED
Conditions: Keratoconjunctivitis Sicca
Interventions: DRUG: CF101
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 TP-271 Oral PK Single Ascending Dose Study
Status: COMPLETED
Conditions: Bacterial Infections
Interventions: DRUG: TP-271
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Aprepitant Treatment to Prevent Postoperative Nausea and Vomiting in Children Undergoing Scoliosis Surgery
Status: NOT_YET_RECRUITING
Conditions: Spinal Fusion|Nausea and Vomiting, Postoperative|Anesthesia
Interventions: DRUG: Aprepitant|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Phase 1b/2a in SLE With Budoputug
Status: NOT_YET_RECRUITING
Conditions: Systemic Lupus Erythematosus|SLE|B Cells
Interventions: DRUG: budoprutug
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The New Pharmaceutical Composition Containing Botulinum Toxin to Treat Atrial Fibrillation
Status: UNKNOWN
Conditions: Atrial Fibrillation|Ischemic Heart Disease
Interventions: DRUG: Pharmaceutical composition containing botulinum toxin|DRUG: 0.9% normal saline|PROCEDURE: Coronary artery bypass grafting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Levosimendan on Diaphragm Function in Mechanically Ventilated Patients
Status: UNKNOWN
Conditions: Muscle Weakness Conditions|Weaning Failure
Interventions: DRUG: Levosimendan|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Improving the Academic Performance of First-Grade Students With Reading and Math Difficulty
Status: ENROLLING_BY_INVITATION
Conditions: Reading Learning Disability|Math Learning Disability
Interventions: BEHAVIORAL: Reading Intervention|BEHAVIORAL: Math Intervention|BEHAVIORAL: Coordinated Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Voxelotor Neurocognitive Function Study
Status: TERMINATED
Conditions: Sickle Cell Disease
Interventions: DRUG: Voxelotor Only Product in Oral Dose Form|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Melatonin in Burning Mouth Syndrome (BMS)
Status: COMPLETED
Conditions: Burning Mouth Syndrome
Interventions: DIETARY_SUPPLEMENT: melatonin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of CAD-based Triage for CXR Interpretation During TB Screening
Status: NOT_YET_RECRUITING
Conditions: Tuberculosis
Interventions: DIAGNOSTIC_TEST: On-site radiologist|DIAGNOSTIC_TEST: CAD-based triage (with INSIGHT CXR software)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Effect of Platelet Rich Plasma and Keratinocyte Suspensions on Wound Healing
Status: COMPLETED
Conditions: Skin Graft
Interventions: BIOLOGICAL: Autologous Platelet Rich Plasma|BIOLOGICAL: Keratinocyte suspension|OTHER: Standard dressings
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neural Stem Cell Based Virotherapy of Newly Diagnosed Malignant Glioma
Status: COMPLETED
Conditions: Glioma|Anaplastic Astrocytoma|Anaplastic Oligodendroglioma|Anaplastic Oligoastrocytoma|Glioblastoma Multiforme|Astrocytoma, Grade III|Astrocytoma, Grade IV|Brain Cancer
Interventions: BIOLOGICAL: Neural stem cells loaded with an oncolytic adenovirus
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study on the Tolerability and Early Efficacy of hLF1-11 in Patients With Proven Candidaemia
Status: WITHDRAWN
Conditions: Candidaemia
Interventions: DRUG: hLF1-11|DRUG: hLF1-11|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Antineoplaston Therapy in Treating Patients With Refractory Stage IV Prostate Cancer
Status: WITHDRAWN
Conditions: Stage IV Prostate Cancer
Interventions: DRUG: Antineoplaston therapy (Atengenal + Astugenal)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of High-flow Humidified Nasal Oxygen During Breaks From Noninvasive Ventilation
Status: COMPLETED
Conditions: Acute Respiratory Failure|Treatment With Noninvasive Positive Pressure Ventilation
Interventions: DEVICE: High-flow humidified nasal oxygen delivery system|DEVICE: Standard oxygen therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Telephone Coaches to Improve Control of Asthma in Children ( PARTNER) Study)
Status: COMPLETED
Conditions: Asthma
Interventions: BEHAVIORAL: Asthma Coaching Program|BEHAVIORAL: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Remediation of Auditory Recognition in Schizophrenia With tDCS
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder
Interventions: DEVICE: Active Transcranial direct current stimulation (tDCS)|DEVICE: Sham Transcranial direct current stimulation (tDCS)|BEHAVIORAL: Auditory Remediation|BEHAVIORAL: Control computer activities
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Role of the Free/Pedunculated Flap in Total Laryngectomy After (Chemo-)Radiotherapy Failure for Laryngeal Carcinoma: Impact on the Risk of Pharyngocutaneous Fistula (PCF)
Status: RECRUITING
Conditions: Larynx Carcinoma
Interventions: PROCEDURE: Primary suture
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: EEG, Cerebral Oximetry, and Arterial to Jugular Venous Lactate to Assess Cerebral Ischemia During Carotid Endarterectomy
Status: COMPLETED
Conditions: Internal Carotid Artery Stenosis
Interventions: DEVICE: EEGo, BIS, FORE-SIGHT cerebral oximeter
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Randomized Controlled Study of Programmed Weaning From Noninvasive Mechanical Ventilation for Acute Exacerbation of Chronic Obstructive Pulmonary Disease
Status: RECRUITING
Conditions: Acute Exacerbation of COPD
Interventions: OTHER: Programmed Weaning From Noninvasive Mechanical Ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety of Cultured Allogeneic Adult Umbilical Cord Derived Mesenchymal Stem Cell Intravenous Infusion for RA
Status: RECRUITING
Conditions: Rheumatoid Arthritis
Interventions: BIOLOGICAL: AlloRx
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Shigella Flexneri 2a Invaplex 50 Vaccine Dose Finding and Assessment of Protection
Status: COMPLETED
Conditions: Shigellosis
Interventions: BIOLOGICAL: 240 µg Shigella flexneri 2a Invaplex 50 vaccine|BIOLOGICAL: 480 µg Shigella flexneri 2a Invaplex 50 vaccine|BIOLOGICAL: 690 Shigella flexneri 2a Invaplex 50 vaccine|OTHER: Shigella challenge strain
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Safety and Efficacy of Celgosivir in Patients With Chronic Hepatitis C Genotype 1 Infection
Status: COMPLETED
Conditions: Hepatitis C, Chronic
Interventions: DRUG: Celgosivir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Motivational Interviewing and Guided Opioid Tapering Support to Promote Postoperative Opioid Cessation
Status: ENROLLING_BY_INVITATION
Conditions: Opioid Cessation
Interventions: BEHAVIORAL: Motivational Interviewing and Guided Opioid Tapering Support|BEHAVIORAL: Enhanced Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transcutaneous Spinal Stimulation: Safety and Feasibility for Trunk Control in Children With Spinal Cord Injury
Status: ACTIVE_NOT_RECRUITING
Conditions: Spinal Cord Injuries
Interventions: DEVICE: Transcutaneous Spinal Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: A Study to Evaluate Whether Participants With Melanoma Prefer Subcutaneous vs Intravenous Administration of Nivolumab and Nivolumab + Relatlimab Fixed-dose Combinations
Status: RECRUITING
Conditions: Melanoma
Interventions: DRUG: relatlimab+nivolumab|DRUG: relatlimab+nivolumab+rHuPH20|DRUG: nivolumab|DRUG: nivolumab+rHuPH20
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Daoist Zhanzhuang and Human Flourishing
Status: NOT_YET_RECRUITING
Conditions: Stress, Physiological|Stress, Psychological|Inflammatory Response|Well-Being, Psychological
Interventions: BEHAVIORAL: Daoist Zhanzhuang|BEHAVIORAL: Sham Wall Squat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effects of GLP-1 in Maturity-Onset Diabetes of The Young (MODY)
Status: COMPLETED
Conditions: Maturity-onset Diabetes of the Young
Interventions: DRUG: liraglutide|DRUG: Glimepiride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Investigation Into Dielectric Assessment of Permittivity and Conductivity in Human Using a Novel Electrical Capacitance Tomography Scanner
Status: RECRUITING
Conditions: Breast Cancer|Benign Breast Disease
Interventions: DEVICE: Breast scan using the Z-scanner|DEVICE: Breast scan using the Z-scanner
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of ERAS-007 as Monotherapy or in Combination With ERAS-601 in Patients With Advanced or Metastatic Solid Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced or Metastatic Solid Tumors
Interventions: DRUG: ERAS-007|DRUG: ERAS-601
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Introductory Clinical Trial for Measuring Patients Before, During, and After an Electrophysiology (EP) Procedure With a Novel, Body-Worn Sensor
Status: COMPLETED
Conditions: Atrial Fibrillation|Ventricular Tachycardia
Interventions: DIAGNOSTIC_TEST: CoVa-2 Monitoring System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Wheat Bioactives and Immune Function
Status: COMPLETED
Conditions: Endocrine, Nutritional, Metabolic and Immunity Disorders
Interventions: DIETARY_SUPPLEMENT: 50 grams of whole wheat bran cereal|DIETARY_SUPPLEMENT: 100 grams of whole wheat bran cereal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Luteal Progesterone Support on Pregnancy Rates With Combined Clomid/ Gonadotropin & IUI
Status: TERMINATED
Conditions: Pregnancy
Interventions: DRUG: Menopur 150 international units|DRUG: Endometrin 100 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Study Evaluating the Clinical Tolerance of Skin Tattoos During MRI Examinations (TATOU - IRM)
Status: RECRUITING
Conditions: Tattoo Disorder|MRI
Interventions: PROCEDURE: MRI|OTHER: Likert scale questionnaire
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Vaccine Therapy in Treating Patients With Metastatic Melanoma
Status: COMPLETED
Conditions: Melanoma (Skin)
Interventions: BIOLOGICAL: aldesleukin|BIOLOGICAL: fowlpox virus vaccine vector|BIOLOGICAL: vaccinia-tyrosinase vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Effect of the Quality of Dietary Proteins on the Sleep Young Elite Athletes and the Obese Adolescent
Status: UNKNOWN
Conditions: Obese Adolescent|Elite Adolescent Athletes
Interventions: DIETARY_SUPPLEMENT: tryptophan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Low Level Laser Therapy for Radiation Induced Dermatitis in H & N Squamous Cell Carcinoma
Status: COMPLETED
Conditions: Radiation Dermatitis
Interventions: DEVICE: THOR Laser System for Low Level Laser Therapy (LLLT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Intrauterine Lidocaine Infusion for Essure Sterilization Procedures
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Lidocaine|DRUG: Sterile Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Feasibility of the ROADE Program
Status: TERMINATED
Conditions: Bulimia Nervosa|Anorexia Nervosa|Binge-Eating Disorder|Avoidant/Restrictive Food Intake Disorder
Interventions: BEHAVIORAL: ROADE Program
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Identification of Non Invasive Biomarkers of Immune Endothelial Injury and Repair Associated With Cardiac Allograft Vasculopathy
Status: UNKNOWN
Conditions: Cardiac Allograft Vasculopathy
Interventions: BIOLOGICAL: blood samples
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Evening Primrose Oil Efficacy in Second Trimester Abortion
Status: UNKNOWN
Conditions: Missed Abortion
Interventions: DRUG: Evening primrose oil(EPO)|DRUG: Placebo - Cap
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Correlation Between the 'Nine Holes Peg Test' Performance and the Triple Stimulation Technique Within a Group a Patients With Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: OTHER: Nine Hole Test|DEVICE: Triple Stimulation Technique
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Pembrolizumab + Platinum Doublets Without Radiation for Programmed Death-ligand 1 (PD-L1) ≥50% Locally Advanced NSCLC
Status: UNKNOWN
Conditions: Locally Advanced Non-small Cell Lung Cancer
Interventions: DRUG: Pembrolizumab|DRUG: Cis Platinum|DRUG: Carboplatin|DRUG: Pemetrexed|DRUG: nab paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Safety & Efficacy of a New Infant Formula With Specific Medical Purpose Containing Human Milk Oligosaccharides
Status: COMPLETED
Conditions: Cow's Milk Protein Allergy
Interventions: OTHER: Test infant formula with HMOs|OTHER: Control infant formula without HMOs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ONCONASE Plus Doxorubicin Versus Doxorubicin Alone For Patients With Malignant Pleural or Peritoneal Mesothelioma Who Have Had No More Than One Prior Chemotherapy Regimen
Status: UNKNOWN
Conditions: Malignant Mesothelioma
Interventions: DRUG: doxorubicin hydrochloride|DRUG: ranpirnase
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Valacyclovir to Suppress HSV and HIV Shedding in Coinfected Persons
Status: COMPLETED
Conditions: Herpes Simplex|HIV Infections
Interventions: DRUG: valacyclovir|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of GnRH Analogue Triptorelin for HIV-1 Reservoir Reduction in ART Treated HIV-1 Infected Patients
Status: UNKNOWN
Conditions: HIV-1-infection
Interventions: DRUG: Triptorelin acetate depot
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Thalamic Deep Brain Stimulation for Spasmodic Dysphonia- DEBUSSY Trial
Status: COMPLETED
Conditions: Spasmodic Dysphonia|Laryngeal Dystonia|Deep Brain Stimulation
Interventions: DEVICE: VIM Thalamic Deep Brain Stimulation ON|DEVICE: VIM Thalamic Deep Brain Stimulation OFF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing the Efficacy, Safety, and Tolerability of Rabeprazole ER 50 mg With Placebo in Subjects With Symptomatic Gastroesophageal Reflux Disease (sGERD)
Status: COMPLETED
Conditions: Symptomatic Gastroesophageal Reflux Disease (sGERD)
Interventions: DRUG: rabeprazole sodium|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Lower Protein Intake and Long-term Risk of Obesity and Cardiovascular Disease
Status: COMPLETED
Conditions: Infant Formula|Growth
Interventions: OTHER: Modified infant formula|OTHER: Standard infant formula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Endothelial Function in Patients With Pulmonary Arterial Hypertension
Status: COMPLETED
Conditions: Hypertension, Pulmonary|Pulmonary Arterial Hypertension|Pathophysiology|Genetics
Interventions: DEVICE: EndoPAT measurement|BIOLOGICAL: Blood Test
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Randomized, Controlled Study of the Safety and Preventive Efficacy of Oral Ganciclovir When Used in Conjunction With An Intravitreal Ganciclovir Implant in the Treatment of Cytomegalovirus Retinitis
Status: COMPLETED
Conditions: Cytomegalovirus Retinitis|HIV Infections
Interventions: DRUG: Ganciclovir
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Randomized Trial of an HIV Prevention and Relationship Education Program for Young Male Couples
Status: COMPLETED
Conditions: Hiv|Chlamydia|Gonorrhea|Relation, Interpersonal
Interventions: BEHAVIORAL: 2GETHER|BEHAVIORAL: Positive Affect Enhancement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Gastro-intestinal Biopotential Recorder by Means of Surface ELEctrodes
Status: NOT_YET_RECRUITING
Conditions: Crohn Disease|Functional Gastrointestinal Disorders|Healthy
Interventions: DEVICE: Gastro-intestinal biopotentials recording
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Placebo In Chronic Back Pain (Phase 2)
Status: COMPLETED
Conditions: Chronic Low Back Pain
Interventions: DRUG: Naproxen|DRUG: Omeprazole|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Probiotics for the Prevention of Immunotherapy Induced Colitis in Patients Receiving Immunotherapy
Status: RECRUITING
Conditions: Malignant Solid Neoplasm
Interventions: PROCEDURE: Biospecimen Collection|DIETARY_SUPPLEMENT: Live Freeze-Dried Lactic Acid Bacteria Probiotic|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Muscle Stem Cell Quality in Atrophy
Status: NOT_YET_RECRUITING
Conditions: Muscle Weakness|Atrophy, Muscle|Cachexia|Sarcopenia|Stem Cell Transplantation|Mesenchymal Stem Cells
Interventions: OTHER: In vitro analyse
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phase I Study of MK-0683 in Combination With Bortezomib in Participants With Multiple Myeloma (MK-0683-098)
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Vorinostat|DRUG: Bortezomib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Onset of Relief From Methacholine-induced Bronchoconstriction With CHF1535 NEXThaler in Asthmatic Patients.
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: CHF1535 NEXThaler|DRUG: CHF1535 pMDI|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ACES - ACE Inhibitors Combined With Exercise for Seniors With Hypertension
Status: ACTIVE_NOT_RECRUITING
Conditions: Hypertension|Aging|Sedentary Lifestyle
Interventions: BEHAVIORAL: Aerobic exercise|DRUG: Perindopril|DRUG: Losartan|DRUG: HCTZ
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of Three Different Pain Blocks for Subjects Undergoing VATS (Video Assisted Thoracoscopic Surgery) Procedure.
Status: COMPLETED
Conditions: Video Assisted Thoracoscopic Surgery|Pain, Postoperative|Pain, Acute
Interventions: DRUG: US Guided Single Shot Paravertebral Block (0.2% ropivicaine infusion)|DRUG: US Guided Paravertebral Catheter (0.2% ropivicaine bolus)|DRUG: Thoracic Epidural (0.125% bupivicaine/hydromorphone)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Paclitaxel and Carboplatin With or Without Epirubicin in Treating Patients With Stage IIB, Stage III, or Stage IV Invasive Ovarian Epithelial, Fallopian Tube, or Peritoneal Cancer
Status: COMPLETED
Conditions: Fallopian Tube Cancer|Ovarian Cancer|Primary Peritoneal Cavity Cancer
Interventions: DRUG: carboplatin|DRUG: epirubicin hydrochloride|DRUG: paclitaxel|PROCEDURE: conventional surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Feasibility Study on the FARAVIEW Technology
Status: ACTIVE_NOT_RECRUITING
Conditions: Atrial Fibrillation|Paroxysmal Atrial Fibrillation|Persistent Atrial Fibrillation
Interventions: DEVICE: Ablation Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparison of the Effects of Tiotropium Inhalation qd and Salmeterol Inhalation Bid on Arterial Blood Gases.
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Tiotropium|DRUG: Salmeterol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Cardiovascular Magnetic Resonance-Guided Radiofrequency-Ablation for Atrial Flutter
Status: TERMINATED
Conditions: Atrial Flutter
Interventions: PROCEDURE: ablation for typical atrial flutter|DEVICE: Vision-MR ablation catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Immunogenicity of Meningococcal B Recombinant Vaccine Administered as Booster Dose at 12, 18 or 24 Months of Age in Toddlers (12-24 Months) Primed With a Three-Dose Immunization Series as Infants in Study V72P12
Status: COMPLETED
Conditions: Meningococcal Disease|Meningococcal Meningitis
Interventions: BIOLOGICAL: rMenB+OMV NZ with routine vaccinations|BIOLOGICAL: rMenB+OMV NZ with routine vaccinations|BIOLOGICAL: rMenB+OMV NZ|BIOLOGICAL: rMenB+OMV NZ|BIOLOGICAL: rMenB+OMV NZ with routine vaccinations|BIOLOGICAL: rMenB+OMV NZ with routine vaccinations|BIOLOGICAL: two doses of rMenB+OMV NZ|BIOLOGICAL: rMenB+OMV NZ with routine vaccinations|BIOLOGICAL: two doses of rMenB+OMV NZ|BIOLOGICAL: rMenB+OMV NZ|BIOLOGICAL: two doses of rMenB+OMV NZ|BIOLOGICAL: rMenB+OMV NZ with routine vaccinations
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study Evaluating EAA-090 in Adult Outpatients With Neuropathic Pain Associated With Diabetic Neuropathy
Status: TERMINATED
Conditions: Diabetes Mellitus|Diabetic Neuropathy, Painful
Interventions: DRUG: EAA-090
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Nicardipine to Avoid Spasm in Trans Radial Percutaneous Coronary Intervention
Status: COMPLETED
Conditions: Spasm Artery
Interventions: DRUG: Nicardipine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Dextran Use for Primary Angioplasty Protection in Acute Myocardial Infarction
Status: UNKNOWN
Conditions: Acute Myocardial Infarction With ST Elevation
Interventions: PROCEDURE: Controlled Reperfusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect Of Itopride On Gastric Emptying And Accommodation In Patients With Functional Dyspepsia
Status: UNKNOWN
Conditions: Functional Dyspepsia|Gastric Emptying|Gastric Accommodation
Interventions: DRUG: Itopride,|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Bioequivalence Study Between Fluticasone Propionate 250 mcg/Blister Oral Inhalation Powder/Respirent Pharmaceuticals vs. FLOVENT DISKUS® 250 mcg/Blister Oral Inhalation Powder /GSK in Healthy Volunteers Under Fasting Conditions
Status: UNKNOWN
Conditions: Asthma|Bioequivalence
Interventions: DRUG: Fluticasone Propionate 250 mcg/Blister Oral Inhalation Powder/Respirent Pharmaceuticals|DRUG: FLOVENT DISKUS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Perioperative Cognitive Training in Thoracic Surgery
Status: WITHDRAWN
Conditions: Pain, Postoperative|Cognitive Function Abnormal|Lung Cancer
Interventions: BEHAVIORAL: COFLEX neurocognitive training|BEHAVIORAL: Crossword puzzles
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: High-Flow Oxygen in Reducing Shortness of Breath Caused by Exercise in Patients With Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Dyspnea|Malignant Neoplasm
Interventions: PROCEDURE: Oxygen Therapy|PROCEDURE: Oxygen Therapy|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration|PROCEDURE: Respiratory Therapy|PROCEDURE: Respiratory Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy and Safety for Medicurtain® in Prevention of Adhesion After Endoscopic Sinus Surgery (Pivotal Study)
Status: COMPLETED
Conditions: Sinusitis|Tissue Adhesion, Surgery-Induced
Interventions: DEVICE: Medicurtain®|DEVICE: GUARDIX-SG®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Preoperative Dexamethasone Study on QOL After Vaginal Reconstructive Surgery for POP
Status: COMPLETED
Conditions: Pelvic Organ Prolapse|PONV
Interventions: DRUG: Dexamethasone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Clinical Evaluation and Comparison of the Tecnis Symfony Optiblue and Tecnis Symfony IOLs
Status: COMPLETED
Conditions: Cataract|Presbyopia
Interventions: DEVICE: Tecnis Symfony Optiblue/Tecnis Symfony Optiblue Toric (Models ZXR00V/ZXW150)|DEVICE: Tecnis Symfony/Tecnis Symfony Toric (Models ZXR00/ZXT150)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Partnering With Patients for Improving Medication Safety During Transitions of Care: Implications for Work System Design
Status: WITHDRAWN
Conditions: Patient Safety|Adverse Drug Event
Interventions: BEHAVIORAL: HomeTeam Toolkit
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: EffectS of Non-nutritive sWeetened Beverages on appetITe During aCtive weigHt Loss
Status: COMPLETED
Conditions: Weight
Interventions: OTHER: Non Nutritive Sweetened Beverages|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Phase 1/2 Study to Investigate Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of HMB-001 in Glanzmann Thrombasthenia
Status: RECRUITING
Conditions: Glanzmann Thrombasthenia
Interventions: DRUG: HMB-001
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Repeated-Dose Evaluation of Use of a Pain Relieving Drug and Safety of OROS Hydromorphone HCI in Patients With Chronic Cancer Pain
Status: COMPLETED
Conditions: Analgesics, Opioid|Pain
Interventions: DRUG: OROS Hydromorphone HCI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing Aczone® Plus Differin® Versus Duac® Plus Differin® in Patients With Severe Facial Acne
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: Dapsone plus Adapalene|DRUG: Clindamycin/benzoyl peroxide plus Adapalene
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pre-Mix Insulin Lispro Treatment for Type 2 Diabetes Patients Who Consume a Light Breakfast
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Insulin Glargine|DRUG: Insulin Lispro Premix (mid-mixture and low-mixture)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Men's Domestic Abuse Check-Up Engages Adult Men Concerned About Their Abusive Behavior and Alcohol or Drug Use
Status: COMPLETED
Conditions: Domestic Violence|Substance Abuse
Interventions: BEHAVIORAL: Motivational Enhancement Therapy|BEHAVIORAL: Educational information
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Injection of Freshly Collected Autologous Adipose Tissue Additional to Bascom's Cleft Lift Surgery
Status: RECRUITING
Conditions: Pilonidal Disease
Interventions: OTHER: injection of freshly collected adipose cells|PROCEDURE: Bascoms Cleft lift procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Peptide Vaccination Associated With Tumoral Immunomodulation in Patients With Advanced Metastatic Melanoma
Status: TERMINATED
Conditions: Metastatic Melanoma
Interventions: DRUG: Vaccine MAGE-3.A1 peptide, or the NA17.A2 peptide + IL-2, IFN-α and GMCSF, Imiquimod.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phosphodiesterase-5 (PDE-5) Inhibition in Heart Transplant Recipients
Status: WITHDRAWN
Conditions: Cardiac Allograft Vasculopathy
Interventions: DRUG: Sildenafil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Treatment of Patients With Advanced Pancreatic Cancer After Gemcitabine Failure.
Status: COMPLETED
Conditions: Pancreatic Adenocarcinoma Advanced or Metastatic
Interventions: DRUG: Paclitaxel|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Effectiveness of Giving an Anti-HIV Drug Combination of Adefovir Dipivoxil Plus Didanosine Plus Efavirenz Plus Lamivudine Once Daily to HIV-Infected Patients
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Efavirenz|DRUG: Adefovir dipivoxil|DRUG: Lamivudine|DRUG: Didanosine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: EFfects of Y-6 SUblingual Tablets foR PaTients With AcUte Ischemic StRokE (FUTURE)
Status: NOT_YET_RECRUITING
Conditions: Acute Ischemic Stroke|Large Vessel Occlusion|Reperfusion
Interventions: DRUG: Low-dose Y-6 sublingual tablets|DRUG: High-dose Y-6 sublingual tablets|DRUG: Low-dose Cilostazol|DRUG: High-dose Cilostazol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficiency of Favourite Versus Predetermined Musical Sequence on Gynecology Pre-operative Anxiety
Status: COMPLETED
Conditions: Surgery|Anxiety State
Interventions: DEVICE: MUSIC CARE|OTHER: PERSONAL PLAY-LIST
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION