pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Immunonutrition for Improving the Efficacy of Immunotherapy in Patients With Metastatic Non-small Cell Lung Cancer
Status: RECRUITING
Conditions: Lung Cancer, Nonsmall Cell
Interventions: DIETARY_SUPPLEMENT: Immunonutrition|OTHER: Control dietary intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: REZILIENT3 (REsearching ZIpaLertinib In Egfr Non-small Cell Lung Cancer Tumors)
Status: RECRUITING
Conditions: Advanced or Metastatic NSCLS With Exon 20 Insertion Mutation
Interventions: DRUG: TAS6417
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study to Evaluate Efficacy and Safety of Fimasartan/Hydrochlorothiazide Combination-therapy
Status: COMPLETED
Conditions: Essential Hypertension
Interventions: DRUG: Fimasartan/HCTZ combination|DRUG: Fimasartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Vitamin D Supplementation as Non-toxic Immunomodulation in Children With Crohn's Disease
Status: TERMINATED
Conditions: Crohn's Disease|Vitamin D Deficiency
Interventions: DRUG: Cholecalciferol|DRUG: Cholecalciferol
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Long-term Follow-up Study (ZOE-LTFU) of Two Studies 110390 (ZOSTER-006) and 113077 (ZOSTER-022) to Assess the Efficacy, Safety, and Immunogenicity Persistence of GSK Biologicals' Herpes Zoster Subunit (HZ/su) Vaccine and Assessment of 1 or 2 Additional Doses in Two Subgroups of Older Adults
Status: COMPLETED
Conditions: Herpes Zoster
Interventions: BIOLOGICAL: Herpes Zoster Vaccine GSK1437173A
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Fetal Assessment of the Myocardium and Evaluation of the Neonate
Status: RECRUITING
Conditions: Newborn Asphyxia|Hemodynamic Instability|Myocardium; Ischemic|Fetal Distress|Labor Pain
Interventions: OTHER: Monitoring with Neobeat heart rate meter|OTHER: Maternal arterial blood gases|OTHER: Amniotic fluid lactate
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Significance of Circulating Tumor Cells in the Treatment of Gastric and Rectal Cancer
Status: COMPLETED
Conditions: Circulating Tumor Cells|Colorectal Cancer|Gastric Cancer
Interventions: PROCEDURE: Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Effect of the Fixed Dose Combination Amlodipine/Valsartan on Central Aortic Blood Pressure in Uncontrolled Essential Hypertension With Amlodipine 5 mg
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Valsartan/amlodipine 80/5 mg tablets|DRUG: Amlodipine 5 mg capsules|DRUG: Amlodipine 10 mg capsules|DRUG: Atenolol 50 mg tablets|DRUG: Atenolol 100 mg tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Real Zero Fluoroscopy Catheter Ablation.
Status: UNKNOWN
Conditions: Atrial Arrhythmia|Ventricular Arrythmia|Arrhythmia|Arrhythmias, Cardiac
Interventions: PROCEDURE: Zero fluoroscopy ablation|PROCEDURE: Conventional ablation without 3D|PROCEDURE: Conventional ablation with 3D
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Impact of Tracheal Tube Fixing Site on Its Mobility During Head Mobilization
Status: COMPLETED
Conditions: Intubation, Intratracheal
Interventions: OTHER: mandible fixation|OTHER: Maxilla fixation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Immunogenicity and Safety of Live Attenuated Varicella Vaccine Combined With Live Attenuated JE Vaccine
Status: COMPLETED
Conditions: Japanese Encephalitis|Chickenpox
Interventions: BIOLOGICAL: Live Attenuated Varicella Vaccine + Live Attenuated JE Vaccine|BIOLOGICAL: Live Attenuated Varicella Vaccine|BIOLOGICAL: live attenuated JE vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Absorption of Rivaroxaban in Patients With Cervical Spinal Cord Injury
Status: WITHDRAWN
Conditions: Spinal Cord Injuries|Thromboembolism
Interventions: DRUG: Rivaroxaban Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Evaluation of the Pharmacokinetic Interaction of Steady State Tipranavir and Ritonavir or Tipranavir and Ritonavir With Single Dose Didanosine in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: TPV + RTV (low dose)|DRUG: TPV + RTV (high dose)|DRUG: ddl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Asses Wellness Using a Brain Sensing Device on Physicians
Status: ACTIVE_NOT_RECRUITING
Conditions: Stress, Emotional|Sleep|Quality of Life
Interventions: DEVICE: Muse S™ Headband system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of the Safety, Pharmacokinetics and Efficacy of HPN-100, in Pediatric Subjects With Urea Cycle Disorders (UCDs)
Status: COMPLETED
Conditions: Urea Cycle Disorders
Interventions: DRUG: HPN-100
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Napoleon Trial: Optimal Treatment for Recurrent Haemorrhoidal Disease
Status: UNKNOWN
Conditions: Hemorrhoids
Interventions: PROCEDURE: RBL versus sutured mucopexy versus haemorrhoidectomy.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Weight Loss and CPAP on OSA and Metabolic Profile Stratified by Craniofacial Phenotype
Status: COMPLETED
Conditions: Obstructive Sleep Apnea
Interventions: BEHAVIORAL: Lifestyle modification|DEVICE: Continuous positive airway pressure (CPAP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dexamethasone and Block Duration in Upper Extremity
Status: TERMINATED
Conditions: Duration of Pain Relief
Interventions: DRUG: Dexamthsone|DRUG: Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Pharmacokinetics (PK), Tolerability and Safety of Two Different Dupilumab Drug Products in Healthy Participants.
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Dupilumab (SAR231893)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Two Formulations of Cyclosporine Ophthalmic Emulsion in Healthy Volunteers and in Patients With Dry Eye
Status: COMPLETED
Conditions: Dry Eye Syndromes
Interventions: DRUG: cyclosporine ophthalmic emulsion Formulation A|DRUG: cyclosporine ophthalmic emulsion Formulation B|DRUG: cyclosporine ophthalmic emulsion Formulation A; cyclosporine ophthalmic emulsion 0.05%|DRUG: cyclosporine ophthalmic emulsion Formulation B; cyclosporine ophthalmic emulsion 0.05%|DRUG: cyclosporine ophthalmic emulsion Formulation A; cyclosporine ophthalmic emulsion Formulation B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Title: Effect of Opioid Receptor Modulation on Alcohol Self-Administration and Neural Response to Alcohol Cues in Heavy Drinkers: Role of OPRM1 Gene Variation
Status: COMPLETED
Conditions: AUD
Interventions: DRUG: Nalmefene|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Hyperpolarized MRI of Lung Transplants
Status: RECRUITING
Conditions: Lung Transplant Rejection
Interventions: COMBINATION_PRODUCT: Hyperpolarized 129-Xenon (MagniXene) MRI of the lung
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Vorinostat in Treating Patients With Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Adult Acute Erythroid Leukemia (M6)|Adult Acute Megakaryoblastic Leukemia (M7)|Adult Acute Minimally Differentiated Myeloid Leukemia (M0)|Adult Acute Monoblastic Leukemia (M5a)|Adult Acute Monocytic Leukemia (M5b)|Adult Acute Myeloblastic Leukemia With Maturation (M2)|Adult Acute Myeloblastic Leukemia Without Maturation (M1)|Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities|Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)|Adult Acute Myeloid Leukemia With t(15;17)(q22;q12)|Adult Acute Myeloid Leukemia With t(16;16)(p13;q22)|Adult Acute Myeloid Leukemia With t(8;21)(q22;q22)|Adult Acute Myelomonocytic Leukemia (M4)|Adult Acute Promyelocytic Leukemia (M3)|Recurrent Adult Acute Myeloid Leukemia|Refractory Cytopenia With Multilineage Dysplasia|Secondary Acute Myeloid Leukemia|Untreated Adult Acute Myeloid Leukemia
Interventions: DRUG: vorinostat|DRUG: vorinostat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Compare the Skin Incision Made by the Electrocautery and Scalpel in Inguinal Hernia Repair
Status: NOT_YET_RECRUITING
Conditions: Post-operative Pain, Acute
Interventions: PROCEDURE: Open Mesh Hernioplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of an Oral Therapeutic Patient Education Session on Physical Activity in Patients With Cancer
Status: COMPLETED
Conditions: Cancer
Interventions: BEHAVIORAL: Therapeutic patient education : oral semi-structured interview|BEHAVIORAL: Therapeutic patient education : booklet (passive)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Bronchiolitis in Infants Placebo Versus Epinephrine and Dexamethasone Study
Status: RECRUITING
Conditions: Bronchiolitis
Interventions: DRUG: Oral dexamethasone|DRUG: Nebulized Epinephrine|DRUG: Oral placebo|DRUG: Nebulized normal saline|DRUG: MDI Epinephrine|DRUG: MDI placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Therapeutic Vaccine Trial of COVID-19 for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection
Status: UNKNOWN
Conditions: COVID
Interventions: BIOLOGICAL: Covax-19™
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Postmenopausal Facial Skin After Estradiol and Genistein Topical Treatment
Status: COMPLETED
Conditions: Atrophy
Interventions: DRUG: isoflavone|DRUG: Estradiol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: To Evaluate the Impact of Consumption of Bioactive Compounds Extracted From Hemp Hull and Black Pepper on Fasting Blood Glucose Levels in People With Pre-diabetes: A Randomized Placebo-Controlled Parallel Arm Trial
Status: RECRUITING
Conditions: Intervention
Interventions: DIETARY_SUPPLEMENT: NCT/NFT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Randomized Trial Evaluating Slow-Release Formulation TAXUS Paclitaxel-Eluting Coronary Stent in the Treatment of In-Stent Restenosis
Status: COMPLETED
Conditions: Coronary Restenosis
Interventions: DEVICE: TAXUS Express2|PROCEDURE: Brachytherapy (beta source)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Furmonertinib in Patients With Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC) With Activating, Including Uncommon, Epidermal Growth Factor Receptor (EGFR) or Human Epidermal Growth Factor Receptor 2 (HER2) Mutations
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-Small Cell Lung Cancer (NSCLC)|Metastatic Non-Small Cell Lung Cancer|Advanced Non-Small Cell Lung Cancer|HER2 Exon 20 Mutations|EGFR Exon 20 Mutations|EGFR Uncommon Mutations, Including G719X and S768I
Interventions: DRUG: Furmonertinib|DRUG: Furmonertinib|DRUG: Furmonertinib|DRUG: Furmonertinib|DRUG: Furmonertinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study of RC48-ADC Combined With Triplizumab For Treatment of Myometrial Invasive Bladder Cancer
Status: NOT_YET_RECRUITING
Conditions: Bladder Cancer
Interventions: DRUG: RC48-ADC|DRUG: Triplizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Niacin On Fatty Acid Trapping
Status: COMPLETED
Conditions: Dyslipidemia
Interventions: DRUG: ER Niacin Oral Fat Challenge|DRUG: IR Niacin Oral Fat Challenge|OTHER: Placebo Oral Fat Challenge
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Study of Genes and the Environment in Patients With Prostate Cancer Residing in the East Anglia, Trent, or West Midlands Regions of the United Kingdom
Status: UNKNOWN
Conditions: Prostate Cancer
Interventions: GENETIC: polymorphism analysis|OTHER: laboratory biomarker analysis|OTHER: questionnaire administration
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy of Pegylated Interferon Plus Ribavirin Plus Nitazoxanide in HCV Genotype 4 and HIV Coinfection
Status: UNKNOWN
Conditions: HCV Coinfection|HIV Infection
Interventions: DRUG: Nitazoxanide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Maintenance Therapy With 5-FU/FA Plus Panitumumab vs. 5-FU/FA Alone After Prior Induction and Re-induction After Progress for 1st-line Treatment of Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: Maintenance Chemotherapy|DRUG: Panitumumab (Within maintenance phase)|DRUG: mFOLFOX6 (Within re-induction phase)|DRUG: Panitumumab (Within re-induction phase)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radiation Therapy Combined With Paclitaxel and Carboplatin in Treating Patients With Stage III Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DRUG: carboplatin|DRUG: paclitaxel|RADIATION: three-dimensional conformal radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Consuming Artificial Sweeteners and Sugar on Cerebral and Physiological Responses
Status: COMPLETED
Conditions: Normal Subjects
Interventions: OTHER: ingestion of a test meal with sweetener|OTHER: ingestion of a test meal with sweetener|OTHER: ingestion of a test meal with water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of Baricitinib (LY3009104) in Participants With Primary Biliary Cholangitis Who do Not Respond or Cannot Take UDCA
Status: TERMINATED
Conditions: Primary Biliary Cholangitis
Interventions: DRUG: Baricitinib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bioimmunoradiotherapy (Cetuximab/RT/Avelumab)
Status: COMPLETED
Conditions: Carcinoma, Squamous Cell of Head and Neck
Interventions: DRUG: avelumab|RADIATION: radiotherapy|DRUG: cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Regenerative Medicine in Ocular Surface: Application of Cell Therapy for Ocular Surface Repair Using Progenitor Cells of Sclerocorneal Limbus Amplified ex Vivo
Status: COMPLETED
Conditions: Unilateral Limbic Insufficiency
Interventions: PROCEDURE: biological replacement corneal surface
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neo-adjuvant Chemotherapy Combined With Stereotactic Body Radiotherapy to the Primary Tumour +/- Durvalumab, +/- Oleclumab in Luminal B Breast Cancer:
Status: ACTIVE_NOT_RECRUITING
Conditions: Luminal B
Interventions: DRUG: Durvalumab|RADIATION: Stereotactic Body Radiotherapy|DRUG: Oleclumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study on the Treatment With Water-filtered Infrared-A (wIRA) Radiation in Patients With Morphea and Sclerotic Graft-versus-host Disease
Status: RECRUITING
Conditions: Morphea (Circumscribed Scleroderma)|Sclerotic Graft-versus-host Disease (GVHD)
Interventions: RADIATION: infrared-A (wIRA)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: R(+)PPX High Dose Treatment of ALS
Status: COMPLETED
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DRUG: R(+) pramipexole dihydrochloride monohydrate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Identification of Necessary Information for Treatment Induction in Newly Diagnosed Acute Lymphoblastic Leukemia/Lymphoma
Status: NOT_YET_RECRUITING
Conditions: Acute Lymphoblastic Leukemia|Lymphoblastic Lymphoma|Mixed Phenotype Acute Leukemia
Interventions: DRUG: Dexamethasone|DRUG: Vincristine|DRUG: Daunorubicin|DRUG: Intrathecal triple therapy (methotrexate + hydrocortisone + cytarabine)|DRUG: Methotrexate|DRUG: Cytarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Test Long-term Treatment With Spesolimab in People With a Skin Condition Disease Called Hidradenitis Suppurativa (HS) Who Took Part in a Previous Study With Spesolimab
Status: RECRUITING
Conditions: Hidradenitis Suppurativa (HS)
Interventions: DRUG: Spesolimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Low-Load Blood Flow Restriction Training With Patients Who Underwent a Total Knee Arthroplasty: a Feasibility Trial
Status: COMPLETED
Conditions: Total Knee Arthroplasty
Interventions: PROCEDURE: Low Load Strength Training under Blood Flow Restriction
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Docetaxel-polymeric Micelles(PM) and Oxaliplatin for Esophageal Carcinoma
Status: UNKNOWN
Conditions: Esophagus Squamous Cell Carcinoma (SCC)|Metastatic Cancer
Interventions: DRUG: Docetaxel-PM|DRUG: Oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mastiha Treatment for Obese With NAFLD Diagnosis
Status: COMPLETED
Conditions: Non Alcoholic Fatty Liver Disease
Interventions: DIETARY_SUPPLEMENT: Mastiha|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Ability of Stereotactic Radiotherapy to Restore the Efficacy of Immunotherapy in Patients With Metastatic Cancer.
Status: NOT_YET_RECRUITING
Conditions: Metastatic Cancer
Interventions: RADIATION: Stereotactic Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing Trifarotene Cream 0.005% to AKLIEF® Cream in the Treatment of Acne Vulgaris
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: Trifarotene Cream 0.005%|DRUG: Placebo|DRUG: AKLIEF® Cream (Trifarotene 0.005%, Galderma Laboratories)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective Pilot Feasibility Study Comparing Envarsus Once-a-day to Tacrolimus Twice-a-day Immunosuppressive Regimen on Drug Bioavailability in Hispanic First Time Kidney Transplant Recipients
Status: RECRUITING
Conditions: Kidney Transplant; Complications|Kidney Transplant Failure and Rejection
Interventions: DRUG: Envarsus|DRUG: Tacrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Evaluation of the Effect of Repetitive Transcranial Magnetic Stimulation in Pain Perception in Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DEVICE: Repetitive Transcranial Magnetic Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Bioequivalence Study of Paroxetine Immediate Release (IR) Tablets Manufactured in GlaxoSmithKline Tianjin (GSKT) and Mississauga Sites in Healthy Chinese Subjects
Status: COMPLETED
Conditions: Anxiety Disorders
Interventions: DRUG: Paroxetine IR tablets A|DRUG: Paroxetine IR tablets B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Blood Pressure Lowering Effects of Angiotensin-(1-7) in Primary Autonomic Failure
Status: TERMINATED
Conditions: Autonomic Nervous System Disorders|Pure Autonomic Failure|Shy-Drager Syndrome|Orthostatic Hypotension, Dysautonomic
Interventions: DRUG: Angiotensin-(1-7)|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Drug-drug Interactions of Guaifenesin and Hydrocodone Bitartrate
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: Humibid®|DRUG: Hydrocodone Bitartrate|DRUG: Humibid® and Hydrocodone Bitartrate tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety, Pharmacokinetics and Pharmacodynamics of Elbasvir (MK-8742) in Hepatitis C Infected Males (MK-8742-002)
Status: COMPLETED
Conditions: Hepatitis, Viral, Human
Interventions: DRUG: Elbasvir|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Functional Near-infrared Spectroscopy for Anxiety Monitoring and Neurofeedback.
Status: RECRUITING
Conditions: Anxiety Disorders
Interventions: DEVICE: AI-fNIRS neurofeedback device|DEVICE: AI-fNIRS neurofeedback device with sham signals
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Intimate Partner Violence and Substance Abuse in a Substance Abuse Treatment Facility
Status: COMPLETED
Conditions: Domestic Violence|Substance Abuse
Interventions: BEHAVIORAL: substance abuse/domestic violence treatment|BEHAVIORAL: Cognitive behavioral therapy addressing substance abuse
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Investigate the Efficacy, Safety, and Tolerability of FBL-MTX in Patients With Rheumatoid Arthritis
Status: RECRUITING
Conditions: Rheumatoid Arthritis
Interventions: DRUG: FBL-MTX
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Reconstruction of the ACL With QT Graft With Bone Plug vs BPTB
Status: RECRUITING
Conditions: Anterior Cruciate Ligament Rupture
Interventions: PROCEDURE: Anterior cruciate ligament Reconstruction with autologous quadriceps tendon graft|PROCEDURE: Anterior cruciate ligament Reconstruction with autologous bone patellar tendon bone graft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Outcomes Management With Electronic Data Technology (COMET) Study
Status: COMPLETED
Conditions: Sleep Apnea, Obstructive
Interventions: DEVICE: Positive Airway Pressure (PAP)|DEVICE: Oral Appliance (OA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I, Dose Escalation Study of Decitabine
Status: COMPLETED
Conditions: Leukemia, Lymphoblastic, Acute|Leukemia, Myeloid Acute|Hematopoetic Myelodysplasia
Interventions: DRUG: Decitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multiple Dose FSH-GEX(TM) in Healthy Volunteers
Status: COMPLETED
Conditions: Female Infertility
Interventions: DRUG: FSH-GEX™|DRUG: recombinant FSH|DRUG: urinary FSH|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: EBRT + Lu-PSMA for N1M0 Prostate Cancer
Status: RECRUITING
Conditions: Prostatic Neoplasm
Interventions: DRUG: 177Lu-PSMA-617|RADIATION: EBRT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Single or Repeated Doses of Glucagon in Participants With Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1|Diabetes Mellitus, Type 2
Interventions: DRUG: Nasal Glucagon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Changes in Patients' Quality of Life With Differences in Seton Application
Status: UNKNOWN
Conditions: Quality of Life|Anal Fistula
Interventions: DEVICE: Alpha type|DEVICE: Beta type|DEVICE: Comfort type
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Standard Versus Super-extended Lymphadenectomy After Neo-adjuvant Chemotherapy for Gastric Cancer
Status: RECRUITING
Conditions: Locally Advanced Gastric Cancer
Interventions: PROCEDURE: Gastrectomy with D2 lymphadenectomy|PROCEDURE: Gastrectomy with D2plus lymphadenectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vitamin D in Vulnerable Adults (VIVA-VA)
Status: COMPLETED
Conditions: Frail Elderly|Vitamin d Deficiency
Interventions: DIETARY_SUPPLEMENT: vitamin D|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Clinical Trial to Study 4 Different Doses of the Vaccine RUTI in Healthy Volunteers
Status: COMPLETED
Conditions: Latent Tuberculosis Infection|Tuberculosis
Interventions: BIOLOGICAL: RUTI|BIOLOGICAL: RUTI|BIOLOGICAL: RUTI|BIOLOGICAL: RUTI|BIOLOGICAL: placebo of the vaccine RUTI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Stimulated Glucagon as a Biomarker of Hypoglycemic Risk in Type 1 Diabetes
Status: RECRUITING
Conditions: Type 1 Diabetes|Hypoglycemia
Interventions: OTHER: Mixed Meal Tolerance Test (MMTT)|OTHER: Arginine Stimulation Test (AST)|OTHER: Home Finger Prick Sample
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Long-term Extension to Study AC-058B301 to Investigate Safety, Tolerability and Disease Control of Ponesimod 20 mg in Patients With Relapsing Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DRUG: Ponesimod
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Dupilumab on Nasal Epithelial Barrier Function in Patients With CRSwNP
Status: RECRUITING
Conditions: Chronic Rhinosinusitis With Nasal Polyps|Chronic Rhinosinusitis Without Nasal Polyps
Interventions: DRUG: Dupilumab 300 MG/2 ML Subcutaneous Solution [DUPIXENT]
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Patient Assessment, and Anxiety and Self-Confidence With Clinical Decision Making in Auscultation Skills With Simulation
Status: COMPLETED
Conditions: Anxiety|Self-Confidence
Interventions: OTHER: education with simulated patient|OTHER: education with simulator|OTHER: control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Assessment of Tooth Shade After De- and Re-Hydration During Clinical Restorative Procedures
Status: UNKNOWN
Conditions: Tooth Shade
Interventions: PROCEDURE: Dehydration|PROCEDURE: Rehydration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CAE Plus LAI in Individuals With Bipolar Disorder at Risk for Treatment Non-adherence (BD-CAEL)
Status: COMPLETED
Conditions: Bipolar Disorder|Medication Adherence|Medication Non Adherence
Interventions: DRUG: Abilify Maintena|BEHAVIORAL: Customized Adherence Enhancement (CAE)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical and Endoscopic Pattern in Children Presented With Upper and Lower Gastrointestinal Bleeding Insohag University Hospital
Status: NOT_YET_RECRUITING
Conditions: Upper and Lower Gastrointestinal Bleeding
Interventions: DEVICE: Endoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Five or Ten Year Colonoscopy for 1-2 Non-Advanced Adenomatous Polyps
Status: RECRUITING
Conditions: Adenocarcinoma of the Colon|Adenocarcinoma of the Rectum
Interventions: PROCEDURE: 5-year and 10 Year Surveillance Colonoscopy after Qualifying Colonoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Eccentric and Trunk Stability Exercise Program Effects in Young Soccer Players
Status: COMPLETED
Conditions: Muscle Strength|Postural Balance
Interventions: OTHER: Sliding leg curl|OTHER: Balance training|OTHER: Core stability
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Open-Label Study of Deoxycholic Acid for the Reduction of Localized Subcutaneous Fat in the Submental Area
Status: COMPLETED
Conditions: Moderate or Severe Submental Fullness
Interventions: DRUG: Deoxycholic acid injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cortical Comminution and Intra-articular Involvement in Distal Radius Fractures Can Predict Radiological Outcome. A Prospective Multicenter Study
Status: COMPLETED
Conditions: Distal Radius Fracture|Radiological Outcome
Interventions: PROCEDURE: Cast immobilization
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of TAK-441 in Adult Patients With Advanced Nonhematologic Malignancies
Status: COMPLETED
Conditions: Advanced Nonhematologic Malignancies|Carcinoma, Basal Cell
Interventions: DRUG: TAK-441
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Trial of Neoadjuvant FOLFOX4 and Cetuximab for Localized Adenocarcinoma of Rectum
Status: TERMINATED
Conditions: Rectal Cancer
Interventions: DRUG: FOLFOX4|DRUG: Cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: NSE Ancillary Study of The Therapeutic Hypothermia After Nonshockable Cardiac Arrest Trial.
Status: COMPLETED
Conditions: Cardiac Arrest|Hypothermia|Critical Care
Interventions: BIOLOGICAL: NSE dosage "hypothermia arm"|BIOLOGICAL: NSE dosage "normothermia arm"
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Sirolimus, Cisplatin, and Gemcitabine Hydrochloride in Treating Patients With Bladder Cancer
Status: COMPLETED
Conditions: Recurrent Bladder Carcinoma|Stage II Bladder Cancer|Stage III Bladder Cancer|Stage IV Bladder Cancer
Interventions: DRUG: Cisplatin|DRUG: Gemcitabine Hydrochloride|DRUG: Sirolimus|PROCEDURE: Cystectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Soft Tissue Integration of Different Abutment Surfaces
Status: COMPLETED
Conditions: Edentulous Alveolar Ridge|Soft Tissue Healing
Interventions: PROCEDURE: Argon plasma pre-treated abutment insertion|PROCEDURE: abutment insertion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multicenter Study of Magnetic Resonance-guided High Intensity Focused Ultrasound for Pain Palliation of Bone Metastases
Status: TERMINATED
Conditions: Bone Metastasis
Interventions: DEVICE: MR-HIFU treatment for pain palliation of bone metastases
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Music on Pain, Comfort and Physiological Parameters During Prematurity Retinopathy Examination
Status: COMPLETED
Conditions: ROP Examination
Interventions: OTHER: Music
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Gait, Stair Climbing and Postural Stability in Knee Osteoarthritis Patients After Hyaluronic Acid Injection
Status: COMPLETED
Conditions: Bilateral Knee Osteoarthritis
Interventions: OTHER: Hyaluronic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Manipulating and Optimising Brain Rhythms for Enhancement of Sleep
Status: COMPLETED
Conditions: Parkinson Disease|MSA - Multiple System Atrophy|Chronic Pain|Epilepsy
Interventions: DEVICE: Deep brain stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of Multiple Ascending Dose of KBL693 in Healthy Participants
Status: COMPLETED
Conditions: Moderate to Severe Asthma
Interventions: DRUG: KBL693|DRUG: KBL693
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: To Determine if Diphenhydramine Works for Nasal Congestion at Two Different Doses
Status: COMPLETED
Conditions: Nasal Congestion
Interventions: DRUG: Diphenhydramine 50 mg|DRUG: Diphenhydramine 25 mg|DRUG: Pseudoephedrine 120 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: CHOEP + High Dose Therapy + Auto SCT for T-Cell Lymphoma
Status: TERMINATED
Conditions: T-cell Non-Hodgkin Lymphoma
Interventions: DRUG: Cyclophosphamide|DRUG: Doxorubicin|DRUG: Vincristine|DRUG: Etoposide|DRUG: Prednisone|DRUG: Filgrastim|DRUG: Plerixafor|PROCEDURE: Stem Cell Collection|DRUG: Palifermin|DRUG: Gemcitabine|DRUG: Busulfan|DRUG: Melphalan|PROCEDURE: Stem Cell Transplant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sorafenib in First-line Treatment of Advanced B Child Hepatocellular Carcinoma
Status: TERMINATED
Conditions: Advanced Adult Hepatocellular Carcinoma
Interventions: OTHER: Best Supportive Care|DRUG: sorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Adenosine Deaminase (ADA) Enzyme Deficiency in Patients With Lymphopenia and/or Elevated Immunoglobulin E
Status: UNKNOWN
Conditions: Adenosine Deaminase Deficiency
Interventions: DIAGNOSTIC_TEST: ADENOSINE DEAMINASE TEST
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Ziv-aflibercept in Eyes With Retinal Diseases and Poor Vision-phase I
Status: UNKNOWN
Conditions: Age Related Macular Degeneration|Central Retinal Vein Occlusion
Interventions: DRUG: ziv-aflibercept drug
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Dexamethasone Oral Preparations to Assess Taste and Acceptance in Children With Asthma and Croup
Status: TERMINATED
Conditions: Asthma|Croup
Interventions: DRUG: Dexamethasone IV for PO|DRUG: Dexamethasone crushed tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Effects of Itraconazole and Etravirine on JNJ-64417184 in Healthy Adult Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: JNJ-64417184|DRUG: Itraconazole|DRUG: Etravirine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High-dose Chemotherapy and Stem Cell Transplantation for Central Nervous System (CNS) Relapse of Aggressive Lymphomas
Status: UNKNOWN
Conditions: Lymphoma, Non-Hodgkin
Interventions: DRUG: Combined systemic and intrathecal chemotherapy followed by HD-ASCT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Povidone Iodine Nasal Irrigation and Gargling to Reduce Viral Load in Asymptomatic Patients With COVID-19
Status: UNKNOWN
Conditions: 2019 Novel Coronavirus Infection
Interventions: OTHER: PVP-I Nasal Irrigation and gargling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Bisoprolol Fumarate Tablet 10 mg Under Fed Condition
Status: COMPLETED
Conditions: Fed
Interventions: DRUG: Bisoprolol Fumarate Tablet 10 mg|DRUG: Bisoprolol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of High Risk Myelodysplastic Syndromes (MDS) Not Candidates for Allogeneic Transplantation of Hematopoietic Progenitors (ALO-HSCT)
Status: UNKNOWN
Conditions: Myelodysplastic Syndromes
Interventions: DRUG: Azacitidine Injection [Vidaza]
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase I Trial to Investigate the Metabolism and Pharmacokinetics as Well as Safety and Tolerability of a Single Dose BI671800 HEA Administered as an Oral Solution of the Choline Salt in Healthy Male Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BI 671800
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open-label Investigation of the Safety and Effectiveness of DIABECELL(R) in Patients With Type I Diabetes Mellitus
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: DEVICE: DIABECELL(R)|DEVICE: DIABECELL(R)|DEVICE: DIABECELL(R)|DEVICE: DIABECELL(R)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Berberine Ursodeoxycholate (HTD1801) Versus Dapagliflozin in Patients With Type 2 Diabetes Inadequately Controlled With Metformin
Status: RECRUITING
Conditions: T2DM (Type 2 Diabetes Mellitus)
Interventions: DRUG: HTD1801|DRUG: Dapagliflozin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Determining Dose Equivalence Between Oral and Transdermal Estrogen Treatment in Women With Turner Syndrome
Status: RECRUITING
Conditions: Turner Syndrome|Hypogonadism; Ovarian|Hormone Replacement Therapy|Estrogen Replacement Therapy|Estrogen Deficiency
Interventions: DRUG: 17-beta estradiol|DRUG: 17-beta estradiol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Role of Hepatic Denervation in the Dysregulation of Glucose Metabolism in Liver Transplant Recipients
Status: WITHDRAWN
Conditions: Diabetes Mellitus, Type 2|Glucose, High Blood|Glucose Metabolism Disorders
Interventions: DRUG: Diazoxide|DRUG: Placebo (for diazoxide)|DRUG: Nicotinic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effectiveness Inspirational Muscle Training
Status: RECRUITING
Conditions: Respiratory Insufficiency
Interventions: OTHER: Inspiratory Muscle Training (IMT)|OTHER: Intensive Physiotherapy (IPT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Pharmacokinetics, and Pharmacodynamic Testing of Rabies mAb CBB 1
Status: NOT_YET_RECRUITING
Conditions: Rabies Virus Infection
Interventions: DRUG: Natural full human monoclonal antibody CBB 1 injection|DRUG: Rabies Human Immunoglobulin (HRIG)|DRUG: Natural full human monoclonal antibody CBB 1 injection placebo|BIOLOGICAL: Lyophilized rabies vaccine for human use (Vero cells)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Atezolizumab and Bevacizumab With Y-90 TARE in Patients With Unresectable Hepatocellular Carcinoma (HCC)
Status: TERMINATED
Conditions: Hepatocellular Carcinoma
Interventions: OTHER: Y-90 TARE|DRUG: Atezolizumab|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Early ABCs Study
Status: COMPLETED
Conditions: Abusive Head Trauma|Early Literacy
Interventions: OTHER: Ready To Learn (RTL)|OTHER: All Babies Cry (ABC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Comparison of The Effectiveness of Intraligamentary and Mandibular Anesthesia on Mandibular Molar Teeth
Status: COMPLETED
Conditions: Anesthesia, Local
Interventions: PROCEDURE: Intraligamentary anaesthesia|PROCEDURE: Mandibular anaesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Can SIS Using Air Bubbles Replace HSG for Fallopian Tubal Patency After Essure Placement
Status: TERMINATED
Conditions: Contraception
Interventions: DEVICE: HyCoSy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Vaccine Therapy, Chemotherapy, and GM-CSF in Treating Patients With Advanced Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: BIOLOGICAL: allogeneic tumor cell vaccine|BIOLOGICAL: recombinant interferon alfa|BIOLOGICAL: sargramostim|DRUG: cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Renal Nerve Stimulation and Renal Denervation in Patients With Sympathetic Ventricular Arrhythmias
Status: TERMINATED
Conditions: Arrhythmias, Cardiac
Interventions: PROCEDURE: RNS and RDN
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pressure Algometry Evaluation of Two Occlusal Splint Designs in Bruxism Management - RCT
Status: UNKNOWN
Conditions: Bruxism|Sleep Disorder
Interventions: DEVICE: Two different occlusal splints
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Investigate the PK and Safety of CKD-393
Status: COMPLETED
Conditions: Type II Diabetes
Interventions: DRUG: CKD-393 formulation I|DRUG: CKD-393 formulation II|DRUG: D501, D759, H053
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT