pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Alprostadil (FemLife Gel) in the Treatment of Female Sexual Arousal Disorder
Status: TERMINATED
Conditions: Female Sexual Arousal Disorder
Interventions: DRUG: FemLife Gel|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Apixaban in Patients With Sickle Cell Disease
Status: TERMINATED
Conditions: Vaso-occlusive Crisis|Reduction in Hospitalizations|Sickle Cell Disease
Interventions: DRUG: Apixaban|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy & Safety Study Evaluating Natural Eggshell Membrane (NEM) in the Treatment of Osteoarthritis
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DIETARY_SUPPLEMENT: NEM|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Prospective Assessment of Quality of Life (QOL) in Pediatric Patients Treated With Radiation Therapy for Brain Tumors and Non-central Nervous System (Non-CNS) Malignancies
Status: ACTIVE_NOT_RECRUITING
Conditions: Brain Tumors|Non-CNS Malignancies
Interventions: OTHER: Quality of Life surveys completed at specified timepoints
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Autologous Hematopoietic Cell Transplantation for Core-binding Factor (CBF) Acute Myeloid Leukemia (AML) in the First Complete Remission (CR1)
Status: UNKNOWN
Conditions: Acute Myeloid Leukemia
Interventions: OTHER: HDAC chemotherapy|OTHER: Autologous HCT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Suprascapular Nerve Block and Subacromial Injection in Hemiplegic Shoulder Pain
Status: COMPLETED
Conditions: Hemiplegia|Pain
Interventions: PROCEDURE: Suprascapular nerve block|PROCEDURE: Subacromial injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Novel Approach to Treating Androgenetic Alopecia in Females With Low Level Laser Therapy
Status: COMPLETED
Conditions: Androgenetic Alopecia
Interventions: DEVICE: Handi-Dome Laser|DEVICE: Incandescent red light source.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mechanical Diagnosis and Treatment and/or Steroid Injections for Lumbar Radiculopathy
Status: TERMINATED
Conditions: Sciatica|Lumbosacral Radiculopathy|Lumbar Disc Rupture
Interventions: OTHER: Exercise (MDT approach)|DRUG: Transforaminal epidural steroid injection (20mg dexamethasone 0.5cc lidocaine 2%)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Virtual Visits (Utilization of Virtual Care in Postoperative Patients to Improve the Patient Experience)
Status: COMPLETED
Conditions: Appendectomy, Laparoscopic|Cholecystectomy, Laparoscopic|Cholecystectomy, Robotic
Interventions: OTHER: Virtual Visit
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Weight Loss-Independent Metabolic Effects of Roux-En-Y Gastric Bypass in Diabetes
Status: ACTIVE_NOT_RECRUITING
Conditions: Obesity|Type 2 Diabetes
Interventions: PROCEDURE: Roux-en-Y gastric bypass surgery|BEHAVIORAL: Low-calorie diet
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Treatment of Sickle Cell Patients Hospitalized in Pain Crisis With Prophylactic Dose Low-molecular-weight Heparin (LMWH) Versus Placebo
Status: COMPLETED
Conditions: Sickle Cell Disease|Vaso-occlusive Crisis
Interventions: DRUG: Placebo|DRUG: Dalteparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Vaginal Compared to Intramuscular Progesterone for Frozen Embryo Transfer
Status: COMPLETED
Conditions: Infertility
Interventions: DRUG: Endometrin® plus Progesterone in Oil (PIO)|DRUG: Progesterone in Oil (PIO) Only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Endocrine Therapy and Abemaciclib on Host and Tumor Immune Cell Repertoire/Function in Advanced ER+/HER2- Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Breast Cancer|Locally Advanced Breast Cancer|Hormone Receptor Positive Tumor
Interventions: DRUG: Abemaciclib|DRUG: Fulvestrant|DRUG: Aromatase Inhibitors
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chemoembolization, Irinotecan Bead, Second Line Chemotherapy Treatment of Unresectable Metastatic Colorectal Cancer
Status: TERMINATED
Conditions: Unresectable Metastatic Colo-rectal Cancer
Interventions: PROCEDURE: Chemoembolization with irinotecan Bead|DRUG: Irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Remote Ischemic Conditioning in Patients With Acute Stroke (RESIST)
Status: COMPLETED
Conditions: Stroke, Acute|Ischemic Stroke|Hemorrhagic Stroke|Intracerebral Hemorrhage|Cerebrovascular Disorders|Central Nervous System Diseases
Interventions: DEVICE: Remote Ischemic Conditioning|DEVICE: Sham Remote Ischemic Conditioning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Chemotherapy IV Carboplatin With Weekly Paclitaxel \Bevacizumab for Primary Ovarian
Status: COMPLETED
Conditions: Ovarian Cancer|Primary Peritoneal Cancer|Fallopian Tube Cancer
Interventions: DRUG: carboplatin|DRUG: Bevacizumab|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multiple Dose Trial of Emraclidine in Elderly Participants and in Participants With Dementia Due to Alzheimer's Disease
Status: RECRUITING
Conditions: Healthy Participants|Alzheimer's Disease Dementia
Interventions: DRUG: Emraclidine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ocular Characteristics in Contact Lens and Spectacle Wear
Status: COMPLETED
Conditions: Visual Acuity
Interventions: DEVICE: Spectacles|DEVICE: ACUVUE OASYS®1-Day with HydraLuxe™ Technology
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ACTiF- Assessment of Closed Tibial Fractures
Status: COMPLETED
Conditions: Tibial Fractures
Interventions: DRUG: CP-533, 536|DRUG: Placebo|PROCEDURE: Standard of Care|DRUG: CP-533,536|DRUG: CP-533,536|DRUG: CP-533,536
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Effects of Belatacept and Anticalcineurins on Endothelial Function in Renal Transplant Patients - <BELAFENDO>
Status: NOT_YET_RECRUITING
Conditions: Kidney Diseases
Interventions: DRUG: Belatacept|DRUG: anticalcineurins
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect Of Hyaluronic Acid And Melatonin With Systemic Administration of Vitamin C On Implant Stability After Immediate Implant in Anterior Region
Status: UNKNOWN
Conditions: Immediate Dental Implant
Interventions: PROCEDURE: immediate implant placement with melatonin hyaluronic acid vit C|PROCEDURE: immediate implant placement without melatonin hyaluronic acid vit C
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Safety and Pharmacokinetics of Rilzabrutinib in Patients With Warm Autoimmune Hemolytic Anemia (wAIHA)
Status: ACTIVE_NOT_RECRUITING
Conditions: Warm Autoimmune Hemolytic Anemia (wAIHA)
Interventions: DRUG: rilzabrutinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aspirin for the Prevention of Recurrent Venous Thromboembolism
Status: UNKNOWN
Conditions: Venous Thromboembolism|Deep Venous Thrombosis|Pulmonary Embolism|Atherosclerosis
Interventions: DRUG: aspirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: TELSYS - TELmisartan Effectiveness in Isolated SYStolic Hypertension Versus Systolic/Diastolic Hypertension Patients Aged 55 or Older
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Telmisartan|DRUG: Telmisartan combined with hydrochlorothiazide
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Concurrent Xeloda and Radiotherapy for Bone Metastases
Status: UNKNOWN
Conditions: Solid Tumors|Bone Metastases
Interventions: DRUG: Xeloda|PROCEDURE: External Beam Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study Evaluating the Safety, Tolerability and Initial Efficacy of SKG0106 Intravitreal Injection in Diabetic Macular Edema (DME) Patients
Status: RECRUITING
Conditions: Diabetic Macular Edema
Interventions: GENETIC: SKG0106 intravitreal injection dose level 1, 2 or 3
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Interest of Using Balanced Fluid for Infusion at the Early Phase of an Acute Cranial Trauma for Limiting Hyperchloremic Acidosis
Status: TERMINATED
Conditions: Head Trauma
Interventions: DRUG: use of a non balced fluid and of a macromolecular fluid|DRUG: use of balanced crystalloids fluid and macromolecular fluid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of LY2951742 (Galcanezumab) in Japanese Participants With Episodic Migraine
Status: COMPLETED
Conditions: Migraine
Interventions: DRUG: Galcanezumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Humoral Immunity Study After a Booster Dose of Soberana Plus (FINLAY-FR-1A) Vaccine Against COVID-19
Status: ENROLLING_BY_INVITATION
Conditions: Humoral Immunity
Interventions: BIOLOGICAL: Protein subunit vaccine Soberana Plus (FINLAY-FR-1A) is a vaccine against COVID-19 produced by The Finlay Vaccine Institute and The Centre of Molecular Immunology (Republic of Cuba)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Extended-Release Liposomal Bupivacaine for Post-Partum Pain Management Following Obstetrical Laceration
Status: COMPLETED
Conditions: Pain, Obstetric
Interventions: DRUG: Bupivacaine Liposome Injectable Product|DRUG: 0.25% plain bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Prospective Evaluation of Clinical Impact of Physiology Versus Optical Coherence Tomography Guided PCI in STEMI Patients Without Undergoing Primary PCI
Status: UNKNOWN
Conditions: ST Elevation Myocardial Infarction
Interventions: PROCEDURE: angiography|PROCEDURE: Thrombus suction|PROCEDURE: Fibrinolytic therapy|BEHAVIORAL: Medication stabilized the condition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Observational, Non-interventional, Non Comparative Real Life Data Collection of Depo-Eligard® 7.5 mg, 22.5 mg and 45 mg in Male Prostate Cancer Patients
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: Depo-Eligard®
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study on the Effect Mechanism of Acupuncture Combined With Swallowing Training in Oral Dysphagia of Stroke
Status: NOT_YET_RECRUITING
Conditions: Dysphagia|Stroke|Oral Phase
Interventions: OTHER: Acupuncture|BEHAVIORAL: Conventional rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination CAR-T Cell Therapy Targeting Hematological Malignancies
Status: UNKNOWN
Conditions: B-cell Malignancies
Interventions: BIOLOGICAL: 4SCAR19 and 4SCAR22|BIOLOGICAL: 4SCAR19 and 4SCAR38|BIOLOGICAL: 4SCAR19 and 4SCAR20|BIOLOGICAL: 4SCAR19 and 4SCAR123|BIOLOGICAL: 4SCAR19 and 4SCAR70|BIOLOGICAL: 4SCAR19 and 4SCAR30
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Pharmacokinetic Parameters and Relative Bioavailability of Sorafenib (XS005) in Healthy Male Subjects
Status: COMPLETED
Conditions: Pharmacokinetics|Bioavailability
Interventions: DRUG: Sorafenib - Period 1|DRUG: XS005 Sorafenib Capsule A - Period 1|DRUG: XS005 Sorafenib Tablet A - Period 1|DRUG: XS005 Sorafenib Capsule A - Period 2|DRUG: XS005 Sorafenib Tablet A - Period 2|DRUG: Sorafenib - Period 2|DRUG: XS005 Sorafenib Tablet A - Period 3|DRUG: Sorafenib - Period 3|DRUG: XS005 Sorafenib Capsule A - Period 3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Comparison Safety and Efficacy of Basal Insulin Lantus® (Insulin Glargine) vs NPH Insulin in Combination With Oral Antidiabetic Drugs (OADs) in Patients With Diabetes Mellitus, Type 2 (DMT2)
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: insulin glargine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study To Evaluate CKD-701 and Lucentis® in Patients With Neovascular(Wet) Age Related Macular Degeneration
Status: COMPLETED
Conditions: Neovascular(Wet) Age Related Macular Degeneration
Interventions: DRUG: CKD-701|DRUG: Lucentis®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Surgery, Radiation Therapy, and Combination Chemotherapy in Treating Patients With Recurrent Head and Neck Cancer
Status: TERMINATED
Conditions: Head and Neck Cancer
Interventions: DRUG: amifostine trihydrate|DRUG: cisplatin|DRUG: fluorouracil|PROCEDURE: surgical procedure|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Study of the Effect of Probiotics on Respiratory Morbidity After Influenza Vaccination of Elderly in Nursing Homes
Status: COMPLETED
Conditions: Respiratory Tract Infections
Interventions: DRUG: Lactobacillus casei Shirota
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Paclitaxel, Ifosfamide, and Cisplatin in Treating Patients With Metastatic Testicular Cancer
Status: COMPLETED
Conditions: Testicular Germ Cell Tumor
Interventions: DRUG: cisplatin|DRUG: ifosfamide|DRUG: paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Ritgens Maneuver for the Prevention of Anal Sphincter Tears at Delivery: A Randomized Controlled Trial
Status: COMPLETED
Conditions: Perineal Lacerations
Interventions: PROCEDURE: Ritgens maneuver|PROCEDURE: Standard care (Manual support of the perineum)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Coronary Calcification Study - Intravascular Lithotripsy for Calcified Lesions
Status: RECRUITING
Conditions: Coronary Artery Calcification
Interventions: DEVICE: Intravascular lithotripsy|DEVICE: Standart therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Laryngeal Nerve Block for Chronic Cough
Status: UNKNOWN
Conditions: Laryngeal Nerve Block|Chronic Neurogenic Cough|Laryngeal Hypersensitivity
Interventions: DRUG: Steroid/Anesthesia Mixture|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of Flow Rate and pH on Muscle Acidosis
Status: UNKNOWN
Conditions: Muscle Acidosis
Interventions: DRUG: Phosphate Buffer Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Clinical Trial for Post Traumatic Stress Disorder
Status: COMPLETED
Conditions: Post Traumatic Stress Disorder (PTSD)
Interventions: DRUG: Medicane (mifepristone)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Radiotherapy Combined With a LHRH (Ant)Agonist Versus Apalutamide in Patients With Biochemical Recurrence After RP
Status: RECRUITING
Conditions: Cancer of Prostate
Interventions: DRUG: Apalutamide|DRUG: Leuprorelin Acetate 45Mg Powder for Injection Suspension Vial|DRUG: Goserelin Acetate 10.8 MG Subcutaneous Implant|DRUG: Triptorelin Pamoate|DRUG: Degarelix acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Virtual Reality Therapy and Transcranial Direct Current Stimulation in Cerebral Palsy.
Status: COMPLETED
Conditions: Cerebral Palsy
Interventions: DEVICE: tDSC-active|DEVICE: tDCS-sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Performance, Safety and Benefit of the Wishbone HA as Bone Graft Substitute, a Pre-market Clinical Investigation
Status: RECRUITING
Conditions: Bone Regeneration|Safety Issues
Interventions: DEVICE: Tooth extraction and bone graft procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Trial to Evaluate Safety, Tolerability, and Parmacokinetics of ALN-TTR02 in Healthy Volunteer Subjects
Status: COMPLETED
Conditions: TTR-mediated Amyloidosis
Interventions: DRUG: ALN-TTR02|DRUG: Sterile Normal Saline (0.9% NaCl)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effects of Therapeutic Touch in Patients With Female Genital Neoplasia: a Randomized Controlled Clinical Trial
Status: UNKNOWN
Conditions: Quality of Life|Gynecologic Neoplasm|Gynecologic Cancer|Palliative Care|Therapeutic Touch|Reiki
Interventions: OTHER: Questionnaires|OTHER: Placebo therapeutic touch|OTHER: Therapeutic touch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Intraarticular Botulinum Toxin A in Ankle Osteoarthritis
Status: COMPLETED
Conditions: Ankle Osteoarthritis
Interventions: DRUG: Botulinum Toxin A (Allergan, Inc, Irvine CA)|DRUG: Hyalgan (Hyalgan, Fidia , Italy)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Laparoscopic Tubal Patency Assessment
Status: COMPLETED
Conditions: Methylene Blue|Laparoscopy|Tubal Patency
Interventions: DRUG: methylen blue &normal saline|DRUG: methylene blue|DRUG: metheylne blue with normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Exploring Novel Interventions to Improve Adherence in Children With Cystic Fibrosis
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DEVICE: Spiro PD personal spirometer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: ISCHEMIA-EXTEND (Extended Follow-up)
Status: ACTIVE_NOT_RECRUITING
Conditions: Cardiovascular Diseases|Coronary Disease|Coronary Artery Disease|Heart Diseases|Myocardial Ischemia
Interventions: PROCEDURE: cardiac catheterization|PROCEDURE: coronary artery bypass graft surgery|PROCEDURE: percutaneous coronary intervention|BEHAVIORAL: Lifestyle|DRUG: Medication
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Multimodal Biopsychosocial Teleprehabilitation for Total Knee Arthroplasty
Status: RECRUITING
Conditions: Total Knee Arthroplasty
Interventions: BEHAVIORAL: Multimodal biopsychosocial teleprehabilitation|OTHER: Best-evidence prehabilitation advice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Trial of Cognitive Behavioral Therapy in Familial Dysautonomia
Status: COMPLETED
Conditions: Dysthymia|Anxiety Disorders|Familial Dysautonomia|Paroxysmal Hypertension|Autosomal Recessive Disease
Interventions: BEHAVIORAL: 8-week CBT Program
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 68Ga-NY104 PET/CT Imaging in Renal Cell Carcinoma
Status: RECRUITING
Conditions: Renal Cell Carcinoma
Interventions: DIAGNOSTIC_TEST: 68Ga-NY104 PET/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Prevelence of IVS 1-6 (T-C) [HBB:c.92 +6 T-C] Gene Mutation in Suspected Cases of β Thalassemia in Assiut University Hospitals
Status: NOT_YET_RECRUITING
Conditions: Beta-Thalassemia
Interventions: GENETIC: ARMS
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Consequences of Obstructive Sleep Apnea Syndrome (OSAS) After Ischemic Subtentorial Stroke.
Status: UNKNOWN
Conditions: Obstructive Sleep Apnea Syndrome|Brain Infarction
Interventions: DEVICE: Continuous Positive Airway pressure-RESPIRONICS|DEVICE: Sham Continuous Positive Airway pressure-RESPIRONICS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of Mindfulness Meditation and Virtual Reality on Laparoscopic Cholecystectomy Patients
Status: NOT_YET_RECRUITING
Conditions: Gall Bladder Disease|Laparoscopic Cholecystectomy
Interventions: BEHAVIORAL: Mindfulness meditation and virtual reality
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Exploring the Use of the Cognitive Orientation to Daily Occupational Performance Approach (CO-OP) With Children, Teenagers and Young Adults With Executive Functions Deficits Following Severe Acquired Brain Injury
Status: COMPLETED
Conditions: Acquired Brain Injury
Interventions: OTHER: CO-OP intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Aspiration of Duodenopancreatic Juice After Secretin Stimulation vs Endoscopic Aspiration for Molecular Analysis of Intraductal Papillary Mucinous Intraductal Neoplasia.
Status: RECRUITING
Conditions: Intraductal Papillary Mucinous Neoplasm of Pancreas
Interventions: DRUG: Secretin|PROCEDURE: Endoscopic aspiration|PROCEDURE: Endoscopic ultrasound-guided fine needle aspiration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Neoadjuvant Immunotherapy for T4 dMMR Colon Cancer
Status: RECRUITING
Conditions: Colon Cancer|Mismatch Repair Deficiency|Immunotherapy
Interventions: DRUG: Camrelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effective Dose of Remimazolam for Sedation in Patients Undergoing Lower Extremity Surgery Under Spinal Anesthesia
Status: COMPLETED
Conditions: Remimazolam|Orthopedic Procedures|Sedatives|Anesthesia, Spinal
Interventions: DRUG: Remimazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: NeuroRegen Scaffold™ With Stem Cells for Chronic Spinal Cord Injury Repair
Status: UNKNOWN
Conditions: Spinal Cord Injury
Interventions: BIOLOGICAL: NeuroRegen scaffold with BMMCs or MSCs transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety, Tolerability, and Efficacy of BIIB017 (Peginterferon Beta-1a) in Pediatric Participants for the Treatment of Relapsing-Remitting Multiple Sclerosis
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Sclerosis, Relapsing-Remitting
Interventions: DRUG: BIIB017 (peginterferon beta-1a)|DRUG: Interferon beta type 1a
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Striving to Quit-Wisconsin Tobacco Quit Line
Status: WITHDRAWN
Conditions: Smoking Cessation|Smoking|Nicotine Dependence
Interventions: BEHAVIORAL: Incentives for abstinence and treatment engagement|BEHAVIORAL: Attendance incentive
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Safety and Efficacy Trial of Aliskiren 150mg , 300 mg Compared to Ramipril 5mg, 10mg in the Elderly
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Aliskiren|DRUG: Ramipril|DRUG: Hydrochlorothiazide|DRUG: Amlodipine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: QUILT-3.046: NANT Melanoma Vaccine: Combination Immunotherapy in Subjects With Melanoma Who Have Progressed On or After Chemotherapy and PD-1/PD-L1 Therapy
Status: WITHDRAWN
Conditions: Melanoma
Interventions: BIOLOGICAL: Avelumab|BIOLOGICAL: Bevacizumab|DRUG: Capecitabine|DRUG: Cisplatin|DRUG: Cyclophosphamide|DRUG: 5-fluorouracil|DRUG: Leucovorin|DRUG: nab-paclitaxel|BIOLOGICAL: Nivolumab|DRUG: omega-3-acid ethyl esters|RADIATION: Stereotactic Body Radiation Therapy|BIOLOGICAL: ALT-803|BIOLOGICAL: ETBX-011|BIOLOGICAL: ETBX-051|BIOLOGICAL: ETBX-061|BIOLOGICAL: GI-6207|BIOLOGICAL: GI-6301|BIOLOGICAL: haNK
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Vapendavir Treatment of Hematopoietic Stem Cell Transplant Subjects With Symptomatic Rhinovirus Infection
Status: WITHDRAWN
Conditions: Rhinovirus|Upper Respiratory Tract Infection
Interventions: DRUG: Vapendavir|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Safety and Pharmakokinetic Study of A4250 Alone or in Combination With A3384
Status: COMPLETED
Conditions: Orphan Cholestatic Liver Diseases|Primary Biliary Cirrhosis|Progressive Familial Intrahepatic Cholestasis|Alagille Syndrome
Interventions: DRUG: A4250|DRUG: CRC (A3384)|DRUG: Questran|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Radiolabeled Monoclonal Antibody Plus Peripheral Stem Cell Transplantation in Treating Patients With Refractory or Recurrent Ovarian Epithelial Cancer
Status: COMPLETED
Conditions: Ovarian Cancer
Interventions: BIOLOGICAL: filgrastim|PROCEDURE: peripheral blood stem cell transplantation|RADIATION: indium In 111 monoclonal antibody MN-14|RADIATION: yttrium Y 90 monoclonal antibody MN-14
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Methadone in Ambulatory Surgery
Status: COMPLETED
Conditions: Post-operative Pain|Anesthesia
Interventions: DRUG: methadone|DRUG: Control (Intra-operative administration of opioids, other than methadone)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Proof of Principle Study to Evaluate the Safety, PK, Viral Shedding and Efficacy of Pentarlandir™ UPPTA for Patients With Early COVID-19
Status: UNKNOWN
Conditions: Coronavirus Disease 2019
Interventions: DRUG: Pentarlandir™ UPPTA|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effect of Dexmedetomidine on Phenylephrine Response During Refractory Septic Shock
Status: TERMINATED
Conditions: Septic Shock|Vasopressor Resistance
Interventions: DRUG: Dexmedetomidine 100 Mcg/mL Intravenous Solution|DRUG: 5% glucose Infusion solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Nicotine Reduction on Adolescent Cigarette Use, Alternative Tobacco Use, and Harm From Tobacco
Status: COMPLETED
Conditions: Nicotine Dependence, Cigarettes, Uncomplicated
Interventions: DRUG: Very Low Nicotine Content Cigarettes|DRUG: Normal Nicotine Content Cigarettes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Ketamine vs. Placebo as Adjunctive Therapies for Severe Alcohol Withdrawal
Status: WITHDRAWN
Conditions: Alcohol Withdrawal
Interventions: DRUG: Ketamine|DRUG: Dexmedetomidine|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Novel Technique for Intrauterine Contraceptive Devices Insertion
Status: COMPLETED
Conditions: Contraception
Interventions: PROCEDURE: Classic group|PROCEDURE: Uterine sounding sparing group|RADIATION: Transvaginal ultrasound|DEVICE: Cu-IUD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Clinical Progression of Mild to Moderate Idiopathic Pulmonary Fibrosis (IPF) Under a Therapy With Esbriet® (Pirfenidone)
Status: COMPLETED
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: DRUG: Pirfenidone
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study on Correlation Between Cytomegalovirus and Ocular Myasthenia Gravis
Status: UNKNOWN
Conditions: Ocular Myasthenia Gravis|Cytomegalovirus Infections
Interventions: DIAGNOSTIC_TEST: Serum acetylcholine receptor antibody, erythrocyte deposition rate, hypersensitive C protein, neostigmine test,thymus CT, low frequency repeated nerve stimulation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Detection of KRAS, NRAS et BRAF Mutations in Plasma Circulating DNA From Patients With Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer Metastatic
Interventions: GENETIC: KRAS, NRAS et BRAF mutation analysis from circulating plasma DNA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: the Effect of Music on Pain and Women Satisfaction During Diagnostic Outpatient Hysteroscopy in Postmenopausal Women
Status: UNKNOWN
Conditions: Hysteroscopy
Interventions: OTHER: Music|OTHER: No music
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effects Assessment of the Polygonatum Kingianum Extract on Endurance Performance and Anti-fatigue
Status: COMPLETED
Conditions: Fatigue
Interventions: DIETARY_SUPPLEMENT: Placebo drink|DIETARY_SUPPLEMENT: Polygonatum kingianum extract drink
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Cost Effectiveness and Efficacy of Kyphoplasty and Vertebroplasty Trial
Status: COMPLETED
Conditions: Osteoporotic Vertebral Compression Fractures
Interventions: PROCEDURE: Kyphoplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: ASPECCT: A Study of Panitumumab Efficacy and Safety Compared to Cetuximab in Patients With KRAS Wild-Type Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: Cetuximab|DRUG: Panitumumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Suture Size in Laparotomy Wound Closure to Prevent Post-operative Complications
Status: ENROLLING_BY_INVITATION
Conditions: Suture Size, Incisional Hernia
Interventions: PROCEDURE: closure of the abdominal fascia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Titanium Prepared Platelet-rich Fibrin in Bone Regeneration in Lateral Window Maxillary Sinus Augmentation
Status: COMPLETED
Conditions: Sinus Lifting
Interventions: OTHER: T-PRF alone|OTHER: T-PRF/Xenograft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Addressing Patients' Expectations of Total Knee Arthroplasty in a Randomized Trial
Status: COMPLETED
Conditions: Knee Osteoarthritis|Arthroplasty, Replacement, Knee
Interventions: BEHAVIORAL: Educational program to address patients' expectations
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Durapore vs. Hy-Tape to Secure The Endotracheal Tube
Status: COMPLETED
Conditions: Erythema
Interventions: DEVICE: DuraporeTM and Hy-Tape®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Robotic Single Port Donor Nephrectomy
Status: COMPLETED
Conditions: Renal Transplant Donor of Left Kidney|Donor Nephrectomy|Robotic Surgery|Single-port
Interventions: DEVICE: da Vinci® Single-Site™
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The OPTI Study in Spain Looks at the History Flare-ups in Patients With Chronic Obstructive Pulmonary Disease (COPD) Treated With Inhaled Steroids.
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Inhaled corticosteroid
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: TC-5214 as Augmentation Therapy in Patients With Refractory Hypertension
Status: TERMINATED
Conditions: Refractory Hypertension
Interventions: DRUG: Placebo|DRUG: TC-5214
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intravitreal Alfibercept for Center Involved DME Previously Managed With Intravitreal Ranibizumab
Status: WITHDRAWN
Conditions: Diabetic Macular Edema
Interventions: DRUG: Intravitreal Aflibercept
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stem Cell Study for Patients With Heart Failure
Status: WITHDRAWN
Conditions: Myocardial Ischemia|Congestive Heart Failure|Cardiovascular Disease
Interventions: BIOLOGICAL: Autologous Stem Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Nivolumab Combined With Cabozantinib Compared to Sunitinib in Previously Untreated Advanced or Metastatic Renal Cell Carcinoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Renal Cell Carcinoma
Interventions: BIOLOGICAL: Nivolumab|DRUG: Cabozantinib|DRUG: Sunitinib|BIOLOGICAL: Ipilimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intervention to Enhance Coping and Help-seeking Among Youth in Foster Care
Status: RECRUITING
Conditions: Adolescent Behavior|Psychosocial Functioning|Coping Behavior|Help-Seeking Behavior|Utilization, Health Care|Depression|Anxiety|Stress Disorders, Post-Traumatic|Emotion Regulation|Child Welfare
Interventions: BEHAVIORAL: Stronger Youth Networks and Coping (SYNC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Biological Mesh Versus Synthetic Mesh in Interdisciplinary RRP With SCP
Status: RECRUITING
Conditions: Intestinal Obstruction|Pelvic Organ Prolapse|Rectal Prolapse
Interventions: DEVICE: interdisciplinary mesh sacro colpopexy with resection rectopexy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Novel Preventive Approach Against Filgrastim-Induced Bone Pain in Cancer Patients
Status: NOT_YET_RECRUITING
Conditions: Breast Cancer|Filgrastim Adverse Reaction
Interventions: DRUG: Placebo|DRUG: famotidine and loratadine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Improving Time-Based Prospective Memory in TBI
Status: ACTIVE_NOT_RECRUITING
Conditions: Traumatic Brain Injury
Interventions: BEHAVIORAL: computer-based cognitive rehabilitation (CBCR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Hetrombopag for Low/Intermediate-1 Risk MDS With Thrombocytopenia
Status: UNKNOWN
Conditions: MDS
Interventions: DRUG: Hetrombopag|DRUG: Stanozolol Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A PMCF Study to Confirm the Performance and Safety of the LeMaitre® TufTex Single Lumen Embolectomy Catheter
Status: RECRUITING
Conditions: Arterial Thromboembolism
Interventions: DEVICE: TufTex Single Lumen Embolectomy Catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Efficacy and Safety of LXI-15028 Comparing With Esomeprazole in the Treatment of Erosive Esophagitis
Status: COMPLETED
Conditions: Erosive Esophagitis (EE)
Interventions: DRUG: LXI-15028 50mg|DRUG: Esomeprazole 40mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Post Mastectomy Pain Syndrome After Preoperative Stellate Ganglion Block for Breast Cancer Surgeries
Status: UNKNOWN
Conditions: Breast Cancer|Breast Pain
Interventions: PROCEDURE: Stellate Ganglion Block|DRUG: Multimodal Analgesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Combined Antioxidant Therapy on Oxidative Stress in Aqueous and Vitreous Humor of Diabetic Retinopathy Patients
Status: COMPLETED
Conditions: Diabetic Retinopathy|Oxidative Stress|Diabetes
Interventions: DRUG: Combined antioxidant therapy|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety Study of SCB-2019 Vaccine as a Booster to COVID-19 Vaccine in Adults
Status: COMPLETED
Conditions: COVID-19
Interventions: BIOLOGICAL: Candidate vaccine, SCB-2019|BIOLOGICAL: Comirnaty Vaccine|BIOLOGICAL: Vaxzevria Vaccine|BIOLOGICAL: CoronaVac Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Changes in Serum Electrolytes at Different Glucose Concentrations + Impact on a Non-invasive Glucose Monitoring Method
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: DEVICE: Non-invasive CGMS|PROCEDURE: Hyperglycemic glucose clamp
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long Term Treatment of Panic Disorder With Clonazepam or Paroxetine
Status: COMPLETED
Conditions: Panic Disorder|Agoraphobia
Interventions: DRUG: Clonazepam|DRUG: Paroxetine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hemodynamics During Induction of General Anesthesia With Medium or Low Remifentanil Doses.
Status: COMPLETED
Conditions: Hemodynamic Instability|Anesthesia, General|Anesthesia, Intravenous
Interventions: DRUG: Remifentanil R2|DRUG: Remifentanil R4|DRUG: Remifentanil R8
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Mindfulness Training and Group Counseling Among Prediabetes and Diabetes Patients
Status: COMPLETED
Conditions: Stress|Diabetes|Pre-Diabetes|Health Behavior|Quality of Life
Interventions: BEHAVIORAL: Mindfulness Based Stress Reduction
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: An Efficacy and Safety Study of Long-acting Risperidone in Participants With Schizophrenia or Schizoaffective Disorders Who Are Receiving Psychiatric Home Care Treatment
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorders
Interventions: DRUG: Risperidone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Pharmacokinetics, Safety and Immunogenicity of BIIB800 Subcutaneously (SC) Compared to Actemra® in Healthy Male Participants
Status: RECRUITING
Conditions: Healthy Volunteer
Interventions: DRUG: BIIB800|DRUG: Actemra
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Plasma Rich in Growth Factors for Treatment of Medication Related Osteonecrosis of the Jaw
Status: UNKNOWN
Conditions: Osteonecrosis Due to Drugs, Jaw
Interventions: PROCEDURE: surgery|DEVICE: PRGF after surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Submucosal Tumor Removal by Endoscopic Excision Therapy
Status: SUSPENDED
Conditions: Submucosal Tumor of Stomach
Interventions: OTHER: removal of submucosal gastric tumor preferably by Full Thickness Resection Device (FTRD)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Hemophagocytic Lymphohistiocytosis (HLH) Evaluation and Research of Clinical, ImmUnoLogic and TranscriptomE Study
Status: RECRUITING
Conditions: Lymphohistiocytosis, Hemophagocytic|Secondary Hemophagocytic Lymphohistiocytosis|Macrophage Activation Syndrome|Hyperinflammatory Syndromes
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Characterization of the Mechanical Properties of the Hamstring Muscle Group in Female.
Status: RECRUITING
Conditions: Menstrual Cycle|Oral Contraceptive Use
Interventions: DIAGNOSTIC_TEST: Hamstring muscles function assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: N-Acetylcysteine for Youth Cannabis Use Disorder
Status: COMPLETED
Conditions: Cannabis Use Disorder
Interventions: DRUG: N-acetyl cysteine|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Short Term Effects of Oceanix Supplementation on Recovery
Status: COMPLETED
Conditions: Oxidative Stress|Muscle Strength|Resistance Training|Muscle Damage|Immune Suppression
Interventions: DIETARY_SUPPLEMENT: Oceanix®|OTHER: Resistance Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT