pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Assessment of the Treatment of Severely Burned With Anabolic Agents on Clinical Outcomes, Recovery and Rehabilitation
Status: TERMINATED
Conditions: Burns
Interventions: PROCEDURE: Stable Isotope Infusion Study|PROCEDURE: Collection of blood and tissues|PROCEDURE: Radiology testing: Dual-energy X-ray absorptiometry (DEXA), ultrasound, MRI|DRUG: Humatrope|DRUG: Ketoconazole|DRUG: Oxandrolone|DRUG: Propranolol|DRUG: Oxandrolone and propranolol combined|DRUG: Humatrope and propranolol combined|DRUG: Placebo|BEHAVIORAL: Exercise--Hospital supervised intensive exercise program|BEHAVIORAL: Home exercise program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Broad Clinical Benefit for Seroquel XR With Flexible Dose as an add-on Therapy in the Treatment of Acute Bipolar Mania Patients With Partial Response to Current Therapy
Status: TERMINATED
Conditions: Acute Bipolar Mania
Interventions: DRUG: Quetiapine fumarate (Seroquel XR)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Remote Ischemic Preconditioning With Postconditioning on Neurologic Outcome
Status: COMPLETED
Conditions: Moyamoya Disease|Remote Ischemic Preconditioning
Interventions: PROCEDURE: RIPC with RIPostC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Pressure Sense Threshold and Tactile Sensation After Lidocaine Iontophoresis Using Interferential Current
Status: COMPLETED
Conditions: Interferential Current Drug Delivery
Interventions: DEVICE: iontophoresis of Lidocaine 10% with interferential current (Dynatron 438)|DRUG: Lidocaine 10% was sprayed at the identified region|DEVICE: interferential current
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Selected Fibres and Flours in Flat Bread on Post-prandial Blood Glucose Responses
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: Control|OTHER: Active 2|OTHER: Active 3|OTHER: Active 4|OTHER: Active 5|OTHER: Active 6|OTHER: Active 7|OTHER: Active 8|OTHER: Active 9|OTHER: Active 10|OTHER: Active 11|OTHER: Active 1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: A Study for Prevention of Kidney Disease in Diabetic Patients (BENEDICT)
Status: COMPLETED
Conditions: Hypertension|Diabetes
Interventions: DRUG: trandolapril|DRUG: trandolapril/verapamil|DRUG: placebo|DRUG: verapamil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Deep Stripping Versus Kneading on Pain, Range of Motion and Function in Knee Osteoarthritis
Status: UNKNOWN
Conditions: Knee Osteoarthritis
Interventions: OTHER: Deep Stripping|OTHER: Kneading
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ex Vivo Microbiological Assessment of an Anti-biofilm Catheter in Acute Dialysis Application
Status: COMPLETED
Conditions: Hemodialysis
Interventions: DEVICE: GamCath® central venous catheter|DEVICE: GamCath Dolphin® Protect central venous catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: NOLA GEM: Feasibility and Acceptability of an mHealth Intervention for Violence-affected PLWH
Status: ACTIVE_NOT_RECRUITING
Conditions: HIV|Mental Health|Substance Use
Interventions: BEHAVIORAL: NOLA GEM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: NS-050/NCNP-03 in Boys With DMD (Meteor50)
Status: NOT_YET_RECRUITING
Conditions: Duchenne Muscular Dystrophy
Interventions: DRUG: NS-050/NCNP-03|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ready to Read: Ready to Read: A School-Based Intervention to Promote Growth Mindset and Reading
Status: UNKNOWN
Conditions: Reading
Interventions: BEHAVIORAL: Reading and Growth Mindset|BEHAVIORAL: Wait-list Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Transdermal Testosterone Patches in Surgically Menopausal Women With Low Libido
Status: COMPLETED
Conditions: Hypoactive Sexual Desire Disorder
Interventions: DRUG: Testosterone Transdermal System|DRUG: placebo patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Knotless Barbed Suture and Standard Suture in Knee Replacement Patients
Status: COMPLETED
Conditions: Knee Osteoarthritis|Hip Osteoarthritis
Interventions: DEVICE: barbed suture|DEVICE: standard suture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Assessing the Behavior of Met DR in Subjects With Kidney Dysfunction
Status: COMPLETED
Conditions: Renal Insufficiency
Interventions: DRUG: Met DR|DRUG: Met XR|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of Auxora in Patients With Severe COVID-19 Pneumonia
Status: COMPLETED
Conditions: Pneumonia
Interventions: DRUG: Auxora|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Effect of Red Wine Consumption on Endothelial Progenitor Cells and Endothelial Function
Status: COMPLETED
Conditions: Endothelial Progenitor Cells Numbers|Endothelial Function (FMD)
Interventions: OTHER: red wine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Partners at Meals - Respite Care and Home (PAM)
Status: COMPLETED
Conditions: Dementia, Alzheimer Type|Weight Loss
Interventions: BEHAVIORAL: Partners at Meals|BEHAVIORAL: Enhanced Usual Condition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluate Tolerability and Safety of BD03 for Prevention of CMV and BKV Reactivation in Kidney Transplant Recipient
Status: UNKNOWN
Conditions: Cytomegalovirus Infections|Preventation of Cytomegalovirus Reactivation|BK Virus Infection|Preventation of BK Virus Reactivation
Interventions: BIOLOGICAL: BD03
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: T-Cell Therapy for Advanced Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer|Metastatic HER2-negative Breast
Interventions: DRUG: Cyclophosphamide|BIOLOGICAL: Mesothelin-targeted T cells|DRUG: AP1903
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of Shortwave Diathermy for the Treatment of Patients With Knee Osteoarthritis
Status: COMPLETED
Conditions: Osteoarthritis, Knee|Menopause
Interventions: DEVICE: Shortwave diathermy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dexmetomedine as an Adjuvant to Bupivacaine in Ultrasound Guided PECS Block
Status: COMPLETED
Conditions: Post Operative Pain
Interventions: PROCEDURE: Pecs block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Learn About How a New Pneumococcal Vaccine Works in Infants
Status: RECRUITING
Conditions: Pneumococcal Disease
Interventions: BIOLOGICAL: PG4|BIOLOGICAL: 20-valent pneumococcal conjugate vaccine (20vPnC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Characterization and Mechanism Research of the Pre-disease State of Obese Type 2 Diabetes Mellitus
Status: NOT_YET_RECRUITING
Conditions: Obese Impaired Glucose Tolerance|Newly Diagnosed Obese Type 2 Diabetic Patients
Interventions: DRUG: 1/bag of Jinlida granules, 3 times/day, taken with hot water.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose Ranging Study of RPL554 in Chronic Obstructive Pulmonary Disease (COPD) Patients
Status: COMPLETED
Conditions: COPD
Interventions: DRUG: RPL554 suspension|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Autologous Tumor-Draining Lymph Node-Derived Lymphocytes as Neoadjuvant Therapy for HER2-Negative Breast Cancer
Status: RECRUITING
Conditions: Breast Neoplasms
Interventions: PROCEDURE: Sentinel Lymph Node Biopsy (SLNB)|DRUG: Doxorubicin|DRUG: Epirubicin|DRUG: Cyclophosphamide|DRUG: Cyclophosphamide|DRUG: Fludarabine|BIOLOGICAL: Tumor-draining lymph node-derived lymphocyte (LNL)|BIOLOGICAL: Interleukin-2|DRUG: Nab-paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dual Target CAR-T Cells in B-cell Lymphoma
Status: UNKNOWN
Conditions: Lymphoma, B-Cell|Relapse/Recurrence|Refractory Lymphoma|Dual-target CAR-T Cells
Interventions: BIOLOGICAL: dual target CAR-T cell therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Pharmacokinetics in Healthy Chinese Subjects
Status: ACTIVE_NOT_RECRUITING
Conditions: The Effects of Clarithromycin or Cyclosporine on Pharmacokinetics of Deuterium Hydrobromide Ramidvir Tablets in Healthy Chinese Subjects
Interventions: DRUG: Mindeudesivir hydrobromide tablets and Clarithromycin tablets|DRUG: Mindeudesivir hydrobromide tablets and Cyclosporine softgels
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study to Evaluate the Efficacy, Safety, and Tolerability of Mirabegron in Older Adult Subjects With Overactive Bladder (OAB)
Status: COMPLETED
Conditions: Overactive Bladder (OAB)
Interventions: DRUG: Mirabegron|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study for 609A in the Treatment of Advanced Undifferentiated Pleomorphic Sarcoma
Status: NOT_YET_RECRUITING
Conditions: Sarcoma, Soft Tissue
Interventions: DRUG: Recombinant anti-PD-1 humanized monoclonal antibody injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Obinutuzumab Containing Conditioning Regimen for Patients With Poor Risk CLL or Richter's Transformation Requiring Allogeneic Stem Cell Transplantation
Status: TERMINATED
Conditions: Chronic Lymphocytic Leukemia|Richter's Transformation
Interventions: BIOLOGICAL: Obinutuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Prolonged Safety and tOLerability of in Migraine Patients in a Long-term OpeN-label Study
Status: COMPLETED
Conditions: Migraine|Migraine Disorders|Migraine Headache
Interventions: BIOLOGICAL: Erenumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Augmentation of the Graft vs. Leukemia Effect Via Checkpoint Blockade With Pembrolizumab
Status: TERMINATED
Conditions: Myelodysplastic Syndromes|Acute Myeloid Leukemia|Acute Lymphoblastic Leukemia
Interventions: DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adjuvant Treatment for Incomplete Resection Thymoma or Thymic Carcinoma
Status: RECRUITING
Conditions: Thymoma and Thymic Carcinoma
Interventions: DRUG: Cisplatin|DRUG: Etoposide|RADIATION: radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Efficacy and Safety of AFQ056 in Reducing Moderate to Severe L-dopa Induced Dyskinesias in Patients With Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson Disease|Dyskinesias
Interventions: DRUG: AFQ056|DRUG: AFQ056|DRUG: AFQ056|DRUG: AFQ056|DRUG: AFQ056|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Colonoscopy by Videocapsuls Versus Standard Colonoscopy. Intra-individual Comparison for the Subject With a Medium or High Risk of Colorectal Cancer.
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: BEHAVIORAL: diet and absorption of ColoPEG|PROCEDURE: Colonoscopy with colic videocapsule|PROCEDURE: Standard colonoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Ramipril and Clopidogrel in Oxidative Stress, Vascular Inflammation and Endothelial Dysfunction in Type 2 Diabetes and Diabetic Nephropathy
Status: UNKNOWN
Conditions: Diabetes Type 2|Diabetic Nephropathy|Vascular Disease
Interventions: DRUG: Ramipril|DRUG: Clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparison Study for Unstable Sacrum/Pelvis and Acetabular Fracture Treated With Open Reduction and Internal Fixation With Minimally Invasive Internal Fixation
Status: RECRUITING
Conditions: Unstable Sacral/Pelvic or Acetabular Fracture
Interventions: PROCEDURE: Tranditional open reduction and internal fixation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Virtual Museum Visit on Dialysis Symptoms and Anxiety in Hemodialysis Patients
Status: NOT_YET_RECRUITING
Conditions: DIALYSIS SYMPTOMS AND ANXIETY
Interventions: OTHER: For the intervention group, a museum visit with virtual reality glasses will be applied.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of ZKAB001 Combined With Carboplatin and Etoposide in the Extensive Small Cell Lung Cancer
Status: UNKNOWN
Conditions: Extensive Stage Small Cell Lung Cancer
Interventions: BIOLOGICAL: recombinant anti-PD-L1 monoclonal antibody injection combined with carboplatin and etoposide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sipuleucel-T Based Autologous Cellular Immunotherapy for Advanced Prostate Cancer
Status: RECRUITING
Conditions: Metastatic Castration-Resistant Prostate Cancer (mCRPC)
Interventions: BIOLOGICAL: Sipuleucel-T
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High Intensity Focused Electromagnetic Field Device for Urinary Incontinence
Status: RECRUITING
Conditions: Stress Urinary Incontinence|Urge Incontinence|Urge and Stress|Overactive Bladder
Interventions: DEVICE: BTL EMSELLA Active treatment|DEVICE: BTL EMSELLA Sham Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Hypertonic Saline and Terlipressin for Sepsis-associated Hypotension
Status: TERMINATED
Conditions: Septic Shock|Sepsis-associated Hypotension
Interventions: DRUG: Hypertonic Saline and Terlipressin|DRUG: Normal saline and norepinephrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dostarlimab for Locally Advanced or Metastatic Cancer (Non-colorectal/Non-endometrial) With Tumor dMMR/MSI
Status: RECRUITING
Conditions: Pancreatic Adenocarcinoma|Ampulla of Vater Carcinoma|Adrenocortical Carcinoma|Neuroendocrine Carcinoma|Soft Tissue Sarcoma|Small Bowel Adenocarcinoma|Duodenum Adenocarcinoma|Gastric Adenocarcinoma
Interventions: DRUG: Dostarlimab|DRUG: Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Adults With Generalized Anxiety Disorder Using Glutamine
Status: TERMINATED
Conditions: Generalized Anxiety Disorder
Interventions: DRUG: L Glutamine|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Seal, Stopping Eczema and Allergy Study
Status: RECRUITING
Conditions: Eczema, Infantile|Eczema|Atopic Dermatitis Eczema|Atopic Dermatitis
Interventions: COMBINATION_PRODUCT: Tri-lipid skin barrier cream (Epiceram)|COMBINATION_PRODUCT: Fluticasone propionate Cream 0.05%|OTHER: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Safety, Tolerability, and Immunogenicity of CRV-101 in Healthy Adult Subjects
Status: COMPLETED
Conditions: Herpes Zoster|Varicella Zoster
Interventions: BIOLOGICAL: CRV 101|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Noble Meta Alloy Coated Catheters in Patients With Long Term Catheterization
Status: UNKNOWN
Conditions: Urinary Tract Infections|Catheter Infection|Catheter-Related Infections|Infection
Interventions: DEVICE: Urethral catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: CHF5993 and CHF1535 pMDI on Lung Hyperinflation and Exercise Endurance Time in Subjects With COPD
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: CHF5993|DRUG: CHF1535|OTHER: Matched placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nasal Septum Autologous Chondrocytes Transplantation for Condylar Resorption After Orthognathic Surgery
Status: COMPLETED
Conditions: Temporomandibular Joint Disorders
Interventions: BIOLOGICAL: Autologous chondrocyte transplantation|PROCEDURE: orthognathic surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sleep Apnea and Refractory Hypertension: Prevalence and Effect of CPAP Treatment
Status: COMPLETED
Conditions: Hypertension|Sleep Apnea
Interventions: DEVICE: cpap treatment during sleep
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: 18F-fluoroestradiol (FES) PET/CT for Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer
Interventions: DIAGNOSTIC_TEST: 18F-fluoroestradiol PET/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Pressure Therapy in the Treatment of Upper Arm of Cerebral Palsy Children
Status: COMPLETED
Conditions: Cerebral Palsy
Interventions: DEVICE: Proprioceptive pressure therapy|DEVICE: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Single Dose Intravenous Iron Isomaltoside in Combination With Oral Iron vs Oral Iron Monotherapy in Patients With Anemia After Postpartum Haemorrhage
Status: UNKNOWN
Conditions: Post Partum Hemorrhage|Anemia
Interventions: DRUG: Iron Isomaltoside 1000|DRUG: Placebo|DRUG: Iberet-Folic-500
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety and Performance of the Affera SpherePVI™ Multi-Ablation System to Treat Paroxysmal Atrial Fibrillation
Status: RECRUITING
Conditions: Atrial Fibrillation
Interventions: DEVICE: SpherePVI™ Catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Does Adding Cryostimulation to Conservative Care Help in Managing Chronic Lateral Epicondylitis? a Pilote Study
Status: UNKNOWN
Conditions: Lateral Epicondylitis
Interventions: DEVICE: cryostimulation|OTHER: conservative care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Sirolimus in Treating Patients With Metastatic or Unresectable Solid Tumors
Status: COMPLETED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: sirolimus|OTHER: laboratory biomarker analysis|OTHER: pharmacological study|PROCEDURE: biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Biomechanics of Gait Pattern Adaptation in Patients After Total Knee Arthroplasty
Status: COMPLETED
Conditions: Knee Arthroplasty|Knee Arthritis Osteoarthritis|Osteoarthritis|Osteoarthritis, Knee|Musculoskeletal Diseases
Interventions: DEVICE: AposTherapy Biomechanical System|OTHER: Physical Therapy Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Safety, Tolerability and Immunogenicity of a 1-Dose Regimen of MRKAd5 HIV-1 Gag Vaccine Versus the ALVAC_HIV Vaccine (V520-019)
Status: COMPLETED
Conditions: HIV-1 Infection
Interventions: BIOLOGICAL: V520|BIOLOGICAL: Comparator: ALVAC-HIV vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: PARTNER 3 Trial: Safety and Effectiveness of the SAPIEN 3 Transcatheter Heart Valve in Low Risk Patients With Aortic Stenosis
Status: ACTIVE_NOT_RECRUITING
Conditions: Aortic Stenosis
Interventions: PROCEDURE: SAVR|DEVICE: SAPIEN 3 THV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of Pembrolizumab Treatment for Disease Relapse After Allogeneic Stem Cell Transplantation
Status: COMPLETED
Conditions: Classical Hodgkin Lymphoma|B-cell Non-Hodgkin Lymphoma|Acute Myeloid Leukemia|Myelodysplastic Syndromes
Interventions: DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial to Confirm a Sustained Virological Suppression Defined as HIV-RNA <50 Copies/ml of 3 Different Doses of Fozivudine in Context to a Standard Zidovudine Based Antiretroviral Therapy Regimen
Status: COMPLETED
Conditions: HIV-1 Infection
Interventions: DRUG: FZD|DRUG: 3TC|DRUG: EFV|DRUG: AZT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Biomarkers in Obese Patients With Knee Osteoarthritis; Weight Maintenance
Status: COMPLETED
Conditions: Osteoarthritis|Obesity
Interventions: DRUG: Liraglutide 3 mg (Saxenda)|DRUG: Liraglutide 3 mg placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Oral Tranexamic Acid vs. Oral Aminocaproic Acid to Reduce Blood Loss After Total Hip Replacement
Status: COMPLETED
Conditions: Blood Loss, Surgical
Interventions: DRUG: Aminocaproic Acid 1000Mg Tab|DRUG: Tranexamic acid tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Urine CXCL10 Chemokine Monitoring Post-renal Transplant
Status: COMPLETED
Conditions: Renal Transplant Rejection
Interventions: DRUG: Rejection treatment according to clinical standard-of-care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Oxaloacetate Supplementation for Emotional PMS
Status: COMPLETED
Conditions: Premenstrual Syndrome (PMS)
Interventions: DIETARY_SUPPLEMENT: Jubilance (100 mg Oxaloacetate/150 mg Ascorbic Acid)|DIETARY_SUPPLEMENT: rice flour (Placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of RO5083945 in Combination With Cisplatin and Gemcitabine or Carboplatin and Paclitaxel in Patients With Advanced or Recurrent Non-Small Cell Lung Cancer of Squamous Histology Who Have Not Received Prior Chemotherapy for The Metastatic Disease
Status: WITHDRAWN
Conditions: Non-Squamous Non-Small Cell Lung Cancer
Interventions: DRUG: RO5083945|DRUG: carboplatin|DRUG: cisplatin|DRUG: gemcitabine|DRUG: paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Post Market Clinical Follow Up to "Patient Reported Outcome" Using a Titanised Polypropylene Mesh (TiLOOP® Bra Pocket)
Status: COMPLETED
Conditions: Breast Reconstruction After Mastectomy|Breast Neoplasm|Breast Cancer|Breast Diseases
Interventions: DEVICE: TiLOOP® Bra Pocket
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Simvastatin as Pulpotomy Agent in Cariously Exposed Permanent Molars
Status: UNKNOWN
Conditions: Reversible Pulpitis
Interventions: PROCEDURE: Complete Pulpotomy using Mineral Trioxide Aggregate|PROCEDURE: Complete Pulpotomy using Simvastain -alphatricalcium phosphate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Exploring the Molecular Basis to Healthy Obesity: The Diabetes Risk Assessment Study
Status: COMPLETED
Conditions: Obesity|Type-2 Diabetes|Metabolic Syndrome|Dyslipidemia
Interventions: OTHER: High fat/high calorie meal
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Less Is More: Optimized Pharmacotherapy With Improved coNtinuity of CarE in hospitaLized oLder peOple
Status: RECRUITING
Conditions: Polypharmacy|Medication Review
Interventions: OTHER: Transitional Multidisciplinary Pharmacotherapeutic Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: PD-1 Inhibitors Consolidation in Extensive-stage Small Cell Lung Cancer
Status: UNKNOWN
Conditions: Extensive-stage Small Cell Lung Cancer|Radiotherapy|Immunotherapy
Interventions: DRUG: PD-1 inhibitor JS-001
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exercise Program for Maintaining Physical Function and Frailty on Dwelling Older Adults
Status: TERMINATED
Conditions: Frailty
Interventions: OTHER: Exercise|OTHER: Recommendations for active lifestyle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Interest of High Flow Nasal Cannula Oxygen Therapy in Pediatric Intensive Care Unit
Status: UNKNOWN
Conditions: Weaning Failure
Interventions: DEVICE: High Flow Nasal Cannula Oxygen therapy (OPTIFLOW®)|DEVICE: Conventional oxygen therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy and Safety of Ad5FGF-4 for Myocardial Ischemia in Patients With Stable Angina Due to Coronary Artery Disease
Status: TERMINATED
Conditions: Angina, Stable
Interventions: GENETIC: Alferminogene tadenovec
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Manage Macular Cystoid Edema With Retinal Vein Obstruction Using Traditional Chinese Medicine and Ranibizumab
Status: RECRUITING
Conditions: Macular Cystoid Edema
Interventions: DRUG: Jueling Mingmu decoction|DRUG: intravitreal injections of 0.5mg ranibizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Vitamin B3 in Patients With Ataxia Telangiectasia
Status: COMPLETED
Conditions: Ataxia Telangiectasia|ATM Gene Mutation
Interventions: DIETARY_SUPPLEMENT: Vitamin B3
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Parkinson's And Zoledronic Acid
Status: RECRUITING
Conditions: Parkinson Disease|Osteoporosis|Parkinsonism|Parkinson's Disease and Parkinsonism|Atypical Parkinsonism|Progressive Supranuclear Palsy|Multiple System Atrophy|Vascular Parkinsonism|Dementia With Lewy Bodies
Interventions: DRUG: Zoledronic Acid 5Mg/Bag 100Ml Inj|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Open-label Study to Evaluate the Safety and Tolerability of iv Lacosamide in Japanese Adults With Partial-onset Seizures
Status: COMPLETED
Conditions: Epilepsy|Partial-onset Seizures
Interventions: DRUG: Lacosamide (200 mg/20 mL)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Investigate the Pharmacokinetics (PK), Safety and Tolerability of Retosiban in Healthy Japanese Women
Status: COMPLETED
Conditions: Obstetric Labour, Premature
Interventions: DRUG: Retosiban solution for Infusion|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Standardized Treatment of Integrative Medicine With the Severe IgA Nephropath
Status: UNKNOWN
Conditions: IgA Nephropathy
Interventions: DRUG: Chinese Herb Prescription Granule plus prednisone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: The PROOF Study: The PICC Related Obstruction Of Flow Study
Status: TERMINATED
Conditions: Patients Indicated for a PICC for Any Medical Condition
Interventions: DEVICE: BioFlo™ Peripherally Inserted Central Catheter (PICC)|DEVICE: Bard® Dual-Lumen PowerPICC SOLO2®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Testing the Adipose Expandability Hypothesis In Vivo During Overfeeding
Status: RECRUITING
Conditions: Overweight and Obesity|Metabolic Syndrome
Interventions: BEHAVIORAL: Control|BEHAVIORAL: Overfeeding
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Study to Evaluate the Safety and Efficacy of Dural Repair Patch in Neurosurgical Repairs
Status: UNKNOWN
Conditions: Neurosurgical Repairs
Interventions: DEVICE: ReDura Onlay|DEVICE: DuraGen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effects of App-based Versus Personal On-site Instruction on Neuromuscular Activity in Injury Prevention Exercises
Status: COMPLETED
Conditions: Musculoskeletal Injury|Injury, Knee
Interventions: BEHAVIORAL: APP|BEHAVIORAL: PHY
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: ENTRUST - TAArget® Thoracic Stent Graft Clinical Trial
Status: UNKNOWN
Conditions: Thoracic Aortic Aneurysm
Interventions: DEVICE: Endovascular repair of TAA in the descending Thoracic Aorta
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Applying PET/MR in Oncology - a Prospective Project
Status: UNKNOWN
Conditions: Lymphoma|Nasopharyngeal Cancer|Esophageal Cancer|Cervical Cancer|Hepatobiliary Cancer|Pancreatic Cancer|Sarcoma|Prostate Cancer
Interventions: DIAGNOSTIC_TEST: PET/MR scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Basket Combination Study of Inhibitors of DNA Damage Response, Angiogenesis and Programmed Death Ligand 1 in Patients With Advanced Solid Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Mismatch Repair Proficient Colorectal Cancer|Pancreatic Adenocarcinoma|Leiomyosarcoma
Interventions: BIOLOGICAL: Durvalumab|DRUG: Olaparib|DRUG: Cediranib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transcranial Electrical Stimulation (TES) for the Treatment of Depression.
Status: COMPLETED
Conditions: Major Depression
Interventions: DEVICE: Sham TES|DEVICE: Active TES
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I Safety Study of B/HPIV3/S-6P Vaccine Via Nasal Spray in Adults
Status: ACTIVE_NOT_RECRUITING
Conditions: SARS-CoV-2 Infection
Interventions: BIOLOGICAL: B/HPIV3/S-6P
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Connective Tissue Diseases and Vitamin D Deficiency
Status: UNKNOWN
Conditions: Connective Tissue Diseases
Interventions: OTHER: Systemic lupus erythematosus group|OTHER: Systemic sclerosis group|OTHER: Healthy control group
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Surgeon-performed Outpatient Transoral and Transcervical Ultrasound of the Oropharynx
Status: ACTIVE_NOT_RECRUITING
Conditions: Oropharynx Cancer|Tonsil Cancer|Base of the Tongue Tumor|Tonsil Hypertrophy|Tonsil Ulcer|Tonsil Neoplasm|Tonsil Lymphoma|Base of Tongue Carcinoma
Interventions: DIAGNOSTIC_TEST: Transoral Ultrasound|DIAGNOSTIC_TEST: Transcervical Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Implementation of a Psychological Online Intervention for Low to Moderate Depression in Primary Health Care
Status: UNKNOWN
Conditions: Depressive Disorder|Depressive Symptoms|Depression
Interventions: BEHAVIORAL: "Sonreír es diveritdo" - Smiling is fun
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy in Treating Patients With AIDS-Related Hodgkin's Disease
Status: COMPLETED
Conditions: Lymphoma
Interventions: BIOLOGICAL: filgrastim|DRUG: cyclophosphamide|DRUG: etoposide|DRUG: lomustine|DRUG: procarbazine hydrochloride|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TAS-102 Combined With Bevacizumab for Second-line Maintenance Treatment of Advanced Colorectal Cancer
Status: RECRUITING
Conditions: Colorectal Cancer
Interventions: DRUG: TAS-102+bevacizumab|DRUG: Standard chemotherapy+bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tailored Non-Pharmacotherapy Services for Chronic Pain
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Pain
Interventions: BEHAVIORAL: Online CBT-CP based program|BEHAVIORAL: Virtual coach-led CBT-CP based program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Investigating a Standard Regimen in de Novo Kidney Transplant Patients Versus a Calcineurin Inhibitor (CNI)-Free Regimen and a CNI-low Dose Regimen
Status: COMPLETED
Conditions: Kidney Transplantation
Interventions: DRUG: Everolimus|DRUG: Myfortic|DRUG: Sandimmun Optoral|DRUG: Simulect®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Prasugrel Versus Clopidogrel on Platelet Function After Bivalirudin Cessation
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DRUG: Prasugrel|DRUG: Clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Find a Safe and Effective Dose of BI 1701963 Alone and in Combination With BI 3011441 in Patients With Advanced Cancer and a Certain Mutation (Kirsten Rat Sarcoma Viral Oncogene Homologue [KRAS])
Status: TERMINATED
Conditions: Solid Tumors, KRAS Mutation
Interventions: DRUG: BI 1701963|DRUG: BI 3011441
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Potential Drug Interactions Between ALXN2080 and Rosuvastatin and Metformin in Healthy Adult Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Metformin|DRUG: Rosuvastatin|DRUG: ALXN2080
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Computer-based Cognitive Training for Individuals With Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson's Disease|Mild Cognitive Impairment
Interventions: BEHAVIORAL: Brain Fitness|BEHAVIORAL: InSight|BEHAVIORAL: Active Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exploratory Study in Achievement of Improved Survival by Molecular Targeted Chemotherapy and Liver Resection for Not Optimally Resectable Colorectal Liver Metastases
Status: COMPLETED
Conditions: Liver Metastasis|Colorectal Cancer
Interventions: DRUG: Bevacizumab|DRUG: Cetuximab|DRUG: L-OHP|DRUG: l-LV|DRUG: 5-FU|DRUG: 5-FU
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nutrient Levels Alter Transplant Outcome
Status: COMPLETED
Conditions: Chronic Renal Disease
Interventions: DIETARY_SUPPLEMENT: Arginine and canola oil|DIETARY_SUPPLEMENT: Coromega and Arginine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Peroxisome Proliferator-Activated Receptor-gamma (PPAR-gamma) Agonist in Diabetic End-Stage Renal Disease Patients
Status: COMPLETED
Conditions: Endstage Renal Disease|Diabetes
Interventions: DRUG: Pioglitazone|DRUG: Placebo comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Safety and Efficacy of Multiple-dose of JS002 in Subject With Hyperlipidemia
Status: COMPLETED
Conditions: Hyperlipemia
Interventions: DRUG: JS002|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Partial Synovectomy in Articular Side of Quadriceps Tendon Verified to Reduce Crepitus in Retrospective Study
Status: RECRUITING
Conditions: Osteoarthritis, Knee|Rheumatoid Arthritis, Knee|Spontaneous Osteonecrosis of Knee
Interventions: PROCEDURE: Prepectoral|PROCEDURE: Subpectoral
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Effect of mCIMT Casting on Speech-language Outcomes in Children With Hemiparesis
Status: COMPLETED
Conditions: Speech and Language Disorder|Cerebral Palsy|Hemiplegia|Hemiparesis
Interventions: BEHAVIORAL: Speech-language therapy (SLT)|BEHAVIORAL: Modified constraint-induced movement therapy (mCIMT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Camrelizumab Combined With Neoadjuvant Chemotherapy After Stent Placement for Left-Sided Obstructive Colonic Cancer
Status: RECRUITING
Conditions: Colorectal Cancer|Neoadjuvant Chemotherapy|Stent|Obstruction|Immunotherapy
Interventions: DRUG: Immunotherapy (Camrelizumab)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SWITCH II Early Feasibility Study: Implantable BCI to Control a Digital Device for People With Paralysis
Status: WITHDRAWN
Conditions: Neurologic Disorder|Paralysis|Paralysis; Stroke|Amyotrophic Lateral Sclerosis|Muscular Dystrophies|Spinal Cord Injury|Stroke, Lacunar|Stroke, Brainstem|Upper Limb Injury|Spinal Muscular Atrophy
Interventions: DEVICE: Motor Neuroprosthesis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pemetrexed and Gemcitabine in Patients With Advanced Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DRUG: Pemetrexed|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Core Stabilization Exercises on Pulmonary Functions, Respiratory Muscle Strength and Functional Capacity
Status: COMPLETED
Conditions: Substance Use Disorders|Substance Abuse|Substance Use
Interventions: OTHER: Exercise group|OTHER: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Role of Blood Flow Restriction Therapy in Postoperative Elderly Patients With Hip Fracture
Status: ACTIVE_NOT_RECRUITING
Conditions: Hip Fractures|Muscle Atrophy
Interventions: DEVICE: Blood Flow Restriction with Delfi Tourniquet System Cuff|OTHER: Routine Post-operative Physical Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Four-Way Crossover Study to Compare Ferric Maltol Capsules and Oral Suspension in Healthy Volunteers
Status: UNKNOWN
Conditions: Anemia, Iron Deficiency
Interventions: DRUG: Ferric maltol capsule|DRUG: Ferric maltol suspension
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Analgesic Effect of Ibuprofen, Paracetamol (Acetaminophen), and Paracetamol (Acetaminophen) Plus Codeine on Acute Pain
Status: COMPLETED
Conditions: Surgery
Interventions: DRUG: Placebo|DRUG: Ibuprofen 400 mg|DRUG: Ibuprofen 600 mg|DRUG: Ibuprofen 800 mg|DRUG: Paracetamol (acetaminophen) 500 mg|DRUG: Paracetamol (acetaminophen) 1000 mg|DRUG: Paracetamol (acetaminophen) 1000 mg + codeine 60 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Home-based HIIT to Improve CRC Survivorship: Feasibility and Relationship With Novel Surrogate Biomarkers of CRC Recurrence
Status: COMPLETED
Conditions: Colorectal Cancer|Colorectal Neoplasms|Colorectal Carcinoma|Colonic Neoplasms|Colonic Cancer|Rectal Neoplasms|Rectal Cancer
Interventions: BEHAVIORAL: Home-based high-intensity interval training|BEHAVIORAL: Home-based moderate-intensity continuous exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Cannabidiol (CBD) for the Treatment of Social Anxiety Disorder
Status: COMPLETED
Conditions: Social Anxiety Disorder
Interventions: DRUG: Cannabidiol oral solution|DRUG: Cannabidiol oral solution|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Palliative Care for Patients With Advanced Heart Disease
Status: COMPLETED
Conditions: Acute Coronary Syndrome|Congestive Cardiac Failure|Palliative Care
Interventions: OTHER: Palliative Care Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE