pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Suberoylanilide Hydroxamic Acid in Treating Patients With Metastatic and/or Locally Advanced or Locally Recurrent Thyroid Cancer
Status: COMPLETED
Conditions: Insular Thyroid Cancer|Recurrent Thyroid Cancer|Stage II Follicular Thyroid Cancer|Stage II Papillary Thyroid Cancer|Stage IV Follicular Thyroid Cancer|Stage IV Papillary Thyroid Cancer|Thyroid Gland Medullary Carcinoma
Interventions: DRUG: vorinostat
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Effect of KB001-A on Time-to-Need for Antibiotic Treatment
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: BIOLOGICAL: KB001-A|DRUG: Placebo Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: PPARγ Agonist Treatment for Cocaine Dependence
Status: COMPLETED
Conditions: Cocaine Use Disorder|Alcohol Use Disorder
Interventions: DRUG: Pioglitazone|DRUG: Placebo|BEHAVIORAL: Therapy|BEHAVIORAL: Contingency Management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Fish and Fruit Study: Trial of Fish and Fruit to Improve Survival of Aboriginal People With End Stage Renal Disease
Status: COMPLETED
Conditions: Cardiovascular Diseases
Interventions: BEHAVIORAL: diet of fish and fruit|BEHAVIORAL: fruit and fish|BEHAVIORAL: diet only|BEHAVIORAL: regular diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: EYE-TRAC Advance: Technology Verification (ETA-TV) Cohort 1
Status: COMPLETED
Conditions: Eye-tracking
Interventions: DEVICE: EYE-SYNC eye-tracking device|OTHER: SCAT-3|DEVICE: Desktop Eye-Tracker
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Follow-On Trial to Assess the Long Term Safety and Efficacy of SPM 927 in Painful Distal Diabetic Neuropathy
Status: COMPLETED
Conditions: Diabetic Neuropathy
Interventions: DRUG: lacosamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Study of E7080/Lenvatinib in Chinese Patients With Unresectable Hepatocellular Carcinoma (HCC)
Status: COMPLETED
Conditions: Unresectable Hepatocellular Carcinoma (HCC)
Interventions: DRUG: Lenvatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MyoVoice to Restore Natural, Hands-free Communication to Individuals With Vocal Impairments
Status: UNKNOWN
Conditions: Rehabilitation of Speech and Language Disorders|Speech Disorders|Speech, Alaryngeal|Communication Aids for Disabled|Speech Perception|Speech Intelligibility
Interventions: DEVICE: MyoVoice|DEVICE: Electrolarynx
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Tranexamic Acid Versus Sublingual Misoprostol in Reducing Blood Loss During Elective CS in High Risk Cases
Status: UNKNOWN
Conditions: Post Partum Hemorrhage
Interventions: DRUG: Misoprostol|DRUG: Tranexamic acid|DRUG: Oxytocin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Mavacamten Impact on Myocardial Structure in Participants With Symptomatic Obstructive Hypertrophic Cardiomyopathy
Status: ACTIVE_NOT_RECRUITING
Conditions: Cardiomyopathy, Hypertrophic
Interventions: DRUG: Mavacamten
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of AAV2-GDNF in Adults with Moderate Parkinson's Disease (REGENERATE-PD)
Status: RECRUITING
Conditions: Parkinson Disease
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Methods of Subscapularis Management in Shoulder Arthroplasty: Tenotomy Versus Peel
Status: COMPLETED
Conditions: Subscapularis Injury
Interventions: PROCEDURE: Subscapularis Tenotomy|PROCEDURE: subscapularis peel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects on Exercise Hemodynamics of Vasopressin Blockade by Conivaptan Infusion in Heart Failure Patients
Status: COMPLETED
Conditions: Heart Failure
Interventions: DRUG: Conivaptan|DRUG: Placebo (Dextrose)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Copenhagen Insulin and Metformin Therapy Trial
Status: COMPLETED
Conditions: Type 2 Diabetes|Atherosclerosis|Arteriosclerosis
Interventions: DRUG: metformin|DRUG: insulin detemir|DRUG: insulin aspart + insulin aspart protamin|DRUG: Insulin aspart
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intranasal Oxytocin in Hypothalamic Obesity
Status: COMPLETED
Conditions: Craniopharyngioma|Hypothalamic Obesity
Interventions: DRUG: Syntocinon|DRUG: Placebo (for Syntocinon)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Combination Lumacaftor and Ivacaftor on Markers of Hyperglycemia
Status: TERMINATED
Conditions: Cystic Fibrosis|Diabetes
Interventions: DRUG: lumacaftor-ivacaftor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Study of Neoadjuvant Chemotherapy Plus Trastuzumab and Pertuzumab in HER2-Negative Breast Cancer Patients With Abnormal HER2 Signaling
Status: RECRUITING
Conditions: HER2-negative Breast Cancer
Interventions: DRUG: Doxorubicin|DRUG: Cyclophosphamide|DRUG: Weekly Paclitaxel|DRUG: Trastuzumab|DRUG: Pertuzumab|DIAGNOSTIC_TEST: Celcuity CELx HSF
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Fluorouracil Implants Regional Chemotherapy During the Surgical Treatment for Early Stage Hepatocellular Carcinoma
Status: UNKNOWN
Conditions: Early Stage Hepatocellular Carcinoma
Interventions: PROCEDURE: Radical resection|DRUG: Fluorouracil Implants
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Matched Unrelated or Non-Genotype Identical Related Donor Transplantation For Chronic Granulomatous Disease
Status: COMPLETED
Conditions: Chronic Granulomatous Disease
Interventions: DRUG: Busulfan|BIOLOGICAL: Alemtuzumab|DRUG: Cyclophosphamide|DRUG: Fludarabine|DRUG: Cyclosporine|PROCEDURE: Stem Cell Infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Acute Carbohydrate Intake Intra-training in Crosstraining
Status: ACTIVE_NOT_RECRUITING
Conditions: Recovery
Interventions: DIETARY_SUPPLEMENT: Carbohydrates|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Pembrolizumab and Combination Chemotherapy Before Surgery for the Treatment of Muscle-Invasive Bladder Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Stage II Bladder Cancer AJCC v8|Stage IIIA Bladder Cancer AJCC v8|Muscle Invasive Bladder Carcinoma
Interventions: DRUG: Cisplatin|DRUG: Doxorubicin|DRUG: Methotrexate|BIOLOGICAL: Pegfilgrastim|BIOLOGICAL: Pembrolizumab|PROCEDURE: Radical Cystectomy|DRUG: Vinblastine Sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Performance of POLYTHESE® Vascular Prosthesis
Status: COMPLETED
Conditions: Aneurysm Arterial|Peripheral Arterial Disease|Marfan Syndrome|Arterial Dissections|Ehlers-Danlos Syndrome
Interventions: PROCEDURE: Implantation with POLYTHESE®
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of Atezolizumab in Combination With Carboplatin Plus (+) Paclitaxel With or Without Bevacizumab Compared With Carboplatin+Paclitaxel+Bevacizumab in Participants With Stage IV Non-Squamous Non-Small Cell Lung Cancer (NSCLC)
Status: COMPLETED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: Atezolizumab (MPDL3280A), an engineered anti-PD-L1 antibody|DRUG: Bevacizumab|DRUG: Carboplatin|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Calorie Restriction and Cold Stimuli on Health-related Indicators, Cognitive and Motor Functions
Status: COMPLETED
Conditions: Calorie Deficiency|Fasting|Cold Exposure
Interventions: OTHER: 2-days of zero calorie restriction and whole-body cold-water immersion|OTHER: 6-days of calorie restriction|OTHER: 2-days of zero calorie restriction without whole-body cold-water immersion|OTHER: 2-days of usual diet with whole-body cold-water immersion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Bariatric Surgery and Chronic Renal Disease
Status: UNKNOWN
Conditions: Bariatric Surgery|Chronic Kidney Diseases|Obesity
Interventions: PROCEDURE: Bariatric Surgery + Medical Management of CKD.|OTHER: Medical Management for CKD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Airway Management and Weight in Children
Status: WITHDRAWN
Conditions: Perioperative Respiratory Adverse Events|Airway Management
Interventions: DEVICE: Endotracheal intubation|DEVICE: Laryngeal mask airway
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Neoadjuvant Chemotherapy or Chemoradiotherapy in Resectable Oesophageal Carcinoma（NewEC Study）
Status: COMPLETED
Conditions: Radiotherapy Side Effect|Chemotherapy Effect|Oesophageal Carcinoma|Effect of Drugs|Safety Issues
Interventions: COMBINATION_PRODUCT: Neoadjuvant chemoradiotherapy|PROCEDURE: Oesophagectomy|DRUG: Neoadjuvant chemotherapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparing Efficacy of Sorafenib Versus Sorafenib in Combination With Low-dose FP in Patients With Advanced HCC
Status: UNKNOWN
Conditions: Advanced Hepatocellular Carcinoma|Carcinoma|Carcinoma, Hepatocellular|Liver Neoplasms|Neoplasms
Interventions: DRUG: Sorafenib with Low-dose FP|DRUG: Sorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Test the Combination of Tiotropium and Olodaterol Using the Respimat® Inhaler in People With Chronic Obstructive Pulmonary Disease (COPD) Who Have Different Abilities to Inhale
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Tiotropium + olodaterol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Multilevel Interventions to Increase Adherence to Lung Cancer Screening
Status: ENROLLING_BY_INVITATION
Conditions: Lung Cancer|Lung Cancer Screening
Interventions: OTHER: Stepped Reminders|OTHER: Patient Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Extended Treatment for Smoking Cessation
Status: COMPLETED
Conditions: Smoking Cessation
Interventions: DRUG: Bupropion|DRUG: Nicotine patch|DRUG: Varenicline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Spinal Networks of Balance Learning and Retention in Older Adults
Status: NOT_YET_RECRUITING
Conditions: Aging
Interventions: BEHAVIORAL: Balance Training|DEVICE: Spinal Active tsDCS|DEVICE: Spinal Sham tsDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ticagrelor Monotherapy Compared to Aspirin Monotherapy in Patients With History of ACS
Status: COMPLETED
Conditions: Acute Coronary Syndrome
Interventions: DRUG: Ticagrelor 60 mg|DRUG: Aspirin 100 MG Oral Tablet, Enteric Coated
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Modified Diaphragmatic Training for Gastroesophageal Reflux Disease Post Covid-19
Status: COMPLETED
Conditions: GERD|Post COVID-19 Condition|Diaphragm Issues
Interventions: OTHER: modified diaphragmatic training|OTHER: standard diaphragmatic training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Lactobacillus Reuteri DSM 17938 + Vitamin D3 in the Prevention of RRI in Paediatric Patients
Status: TERMINATED
Conditions: Recurrent Respiratory Tract Infections
Interventions: DIETARY_SUPPLEMENT: Lactobacillus reuteri DSM 17938 + Vitamine D3|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Phase II Study of Alternating Sunitinib and Temsirolimus
Status: COMPLETED
Conditions: Metastatic Renal Cell Carcinoma
Interventions: DRUG: Sunitinib|DRUG: Temsirolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Identifying Effective Technological-based Augmentations to Enhance Outcomes From Self-help Cognitive Behavior Therapy for Binge Eating
Status: ACTIVE_NOT_RECRUITING
Conditions: Binge Eating|Binge-Eating Disorder|Bulimia Nervosa|Bulimia
Interventions: BEHAVIORAL: Base self-help CBT program|BEHAVIORAL: Just-in-time, adaptive intervention (JITAIs) system|BEHAVIORAL: Advanced Digital Data Sharing (ADDS) with Coaches
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Renal Considerations in the Heat Stress Recommendations (Aim2)
Status: COMPLETED
Conditions: Hot Weather; Adverse Effect|Kidney Dysfunction|Kidney Injury|Hyperthermia|Dehydration
Interventions: PROCEDURE: Fluid replacement|PROCEDURE: No fluid replacement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of High-calcium Intake on Appetite, Insulinemia and Incretins
Status: COMPLETED
Conditions: Nutritional and Metabolic Diseases
Interventions: DIETARY_SUPPLEMENT: Calcium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparative Study to Evaluate the Pharmacokinetics of BAT2306 vs Cosentyx® in Healthy Subjects
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: BAT2306|DRUG: Cosentyx (US-licensed)|DRUG: Cosentyx (EU-licensed)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sitagliptin Added-on to Insulin Study (0431-051)
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: sitagliptin phosphate|DRUG: Comparator : placebo (unspecified)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Trichuris Suis Ova (TSO)in Recurrent Remittent Multiple Sclerosis and Clinically Isolated Syndrome
Status: TERMINATED
Conditions: Multiple Sclerosis
Interventions: DRUG: Trichuris suis ova
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Sedatives on Regional Cerebral Oxygen Saturation
Status: WITHDRAWN
Conditions: Cerebral Ischemia-Hypoxia
Interventions: DRUG: Midazolam|DRUG: Dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Topiramate 25 mg Capsules Under Fed Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Topiramate Capsules, 25 mg|DRUG: Topamax® Capsules, 25 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Efficacy and Safety of MP-513 in Combination With Metformin in Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: MP-513 Lowest Dose and Metformin|DRUG: MP-513 Low Dose and Metformin|DRUG: MP-513 Medium Dose and Metformin|DRUG: MP-513 High Dose and Metformin|DRUG: Placebo and Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Monochromatic Light on Incidence of Emergence Delirium in Children
Status: COMPLETED
Conditions: Emergence Delirium|Anesthesia Emergence Delirium
Interventions: DEVICE: Monochromatic blue light
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Orthotic Management of CMC Osteoarthritis
Status: UNKNOWN
Conditions: Arthritis Wrist
Interventions: DEVICE: Orthosis fabrication|DEVICE: Thermal Sensor Monitoring of Orthosis Use|DIAGNOSTIC_TEST: 4D CT Scan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Preoperative, Proton- Radiotherapy Combined With Chemotherapy for Borderline Resectable Pancreatic Cancer
Status: RECRUITING
Conditions: Pancreatic Cancer|Proton Therapy
Interventions: RADIATION: Proton Ions|DRUG: Nab-PACLitaxel|DRUG: Gemcitabine|DRUG: Capecitabine|PROCEDURE: Surgical resection of the pancreas (when feasible)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Addressing Heavy Alcohol Use Consumption With Kudzu
Status: ACTIVE_NOT_RECRUITING
Conditions: Alcohol Use Disorder|Sexually Transmitted Diseases
Interventions: DRUG: Standardized kudzu|OTHER: Placebo|DIAGNOSTIC_TEST: Sexually transmitted infection testing:|BEHAVIORAL: Medical Management (MM) counseling for alcohol use:|DIAGNOSTIC_TEST: Urinalysis for novel alcohol biochemical markers for recent alcohol use:|DIAGNOSTIC_TEST: Dried Blood Spot (DBS) Testing for PEth:|BEHAVIORAL: Behavioral survey measurements:|BEHAVIORAL: Ecological Momentary Assessment procedure:
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Convergence Insufficiency Treatment Study (CITS)
Status: COMPLETED
Conditions: Convergence Insufficiency
Interventions: OTHER: Active home-based computer vergence/accommodative therapy|PROCEDURE: Near target push-ups|OTHER: Placebo home-based computer vergence/accommodative therapy|PROCEDURE: Placebo yoked prism flippers
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Short Term Pharmacokinetic, Pharmacodynamic and Tolerability Study to Compare AOP200704 vs. Esmolol
Status: COMPLETED
Conditions: Healthy Volunteers|Pharmacokinetics/Dynamics Study
Interventions: DRUG: AOP200704|DRUG: Esmolol hydrochloride, infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficiency of Acupuncture Combined Intradermal Sterile Water Application in Acute Renal Colic
Status: NOT_YET_RECRUITING
Conditions: Renal Colic
Interventions: DRUG: Phloroglucinol|COMBINATION_PRODUCT: Acupuncture Combined Intradermal Sterile Water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Imaging of Tumour Microenvironment in Patients With Oropharyngeal Head and Neck Squamous Cell Carcinoma Using RGD PET/CT Imaging
Status: UNKNOWN
Conditions: Oropharyngeal Squamous Cell Carcinoma
Interventions: COMBINATION_PRODUCT: RGD PET/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Study of Internet-delivered, Transdiagnostic Treatments for Anxiety and Depression
Status: ACTIVE_NOT_RECRUITING
Conditions: Anxiety Disorders|Depression
Interventions: BEHAVIORAL: Treatment condition: Internet-administered Unified protocol|BEHAVIORAL: Treatment condition: Internet-administered Affect phobia treatment|OTHER: Treatment condition: Waitlist control|OTHER: Treatment length: 8 weeks|OTHER: Treatment length: 16 weeks|OTHER: Access to a moderated forum|OTHER: No access to a moderated forum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Optical Coherence Tomography and Intravascular Ultrasound for Intermediate Left Main Coronary Artery Lesions
Status: RECRUITING
Conditions: Coronary Disease
Interventions: DIAGNOSTIC_TEST: IVUS (Intravascular Ultrasound) and OCT (Optical Coherence Tomography)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Tissue, Blood, and Body Fluid Sample Collection From Patients With Hematologic Cancer
Status: RECRUITING
Conditions: Chronic Myeloproliferative Disorders|Leukemia|Lymphoma|Lymphoproliferative Disorder|Multiple Myeloma and Plasma Cell Neoplasm|Myelodysplastic Syndromes|Myelodysplastic/Myeloproliferative Neoplasms|Nonmalignant Neoplasm
Interventions: OTHER: biologic sample preservation procedure|OTHER: cytology specimen collection procedure
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Behavioral Management of Phosphorus in Hemodialysis Patients
Status: COMPLETED
Conditions: Cardiovascular Disease (CKD)|Hyperphosphatemia
Interventions: BEHAVIORAL: Education (Edu)|BEHAVIORAL: SM intervention|BEHAVIORAL: Social Cognitive Therapy (SCT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chronic Low Back Pain Rehabilitation in Primary Care: an RCT
Status: COMPLETED
Conditions: Low Back Pain|Chronic Pain|Musculoskeletal Pain
Interventions: OTHER: Back on Track intervention|OTHER: Primary care as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study in Ovarian, Non-Small Cell Lung, Prostate, Colorectal, Gastroesophageal Cancers, and Squamous Cell Carcinoma of the Head and Neck
Status: COMPLETED
Conditions: Ovarian Cancer|Non Small Cell Lung Cancer|Prostate Cancer|Colorectal Cancer|Gastric Cancer|Esophageal Cancer|Cancer of Head and Neck
Interventions: DRUG: LY2523355|DRUG: pegfilgrastim
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Safety and Efficacy of Long-term Treatment of PINS Stimulator System for Patients With Alzheimer's Disease
Status: UNKNOWN
Conditions: Alzheimer's Disease
Interventions: DEVICE: Deep Brain Stimulation (Beijing PINS Medical Co., Ltd)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 3 Study of Bardoxolone Methyl in Patients With Diabetic Kidney Disease; AYAME Study
Status: TERMINATED
Conditions: Diabetic Kidney Disease
Interventions: DRUG: Bardoxolone methyl|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Parental Perspectives of Using Toy Cars on Social Interactions of Preschool Children With Mobility Impairments
Status: COMPLETED
Conditions: Children|Mobility Limitation|Spina Bifida|Attitude to Health
Interventions: DEVICE: Toy car
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Omega 3 Lipid Emulsions and Liver Transplantation
Status: UNKNOWN
Conditions: Ischemia Re-perfusion Injury
Interventions: DIETARY_SUPPLEMENT: SMOFLipid|DIETARY_SUPPLEMENT: equivalent volume of 10% glucose solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Ixazomib Citrate and Lenalidomide After Stem Cell Transplant in Treating Patients With Newly Diagnosed Multiple Myeloma
Status: COMPLETED
Conditions: Hematopoietic Cell Transplantation Recipient|Plasma Cell Myeloma
Interventions: DRUG: Ixazomib Citrate|DRUG: Lenalidomide|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Rituximab and Cyclophosphamide, Doxorubicin, Vincristine, Prednisone (CHOP) in Patients With HIV Associated Non-Hodgkin's Lymphoma
Status: TERMINATED
Conditions: AIDS Related Lymphoma
Interventions: DRUG: rituximab|DRUG: CHOP
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Dupilumab Monotherapy Administered to Adult Patients With Moderate-to-Severe Atopic Dermatitis
Status: COMPLETED
Conditions: Dermatitis, Atopic
Interventions: DRUG: Dupilumab|DRUG: Placebo (for Dupilumab)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Methods of Lumbar Sympathetic Ganglion Block: Distance vs Angle
Status: UNKNOWN
Conditions: Lumbar Sympathetic Ganglion Block Indication: Neuropathic Pain, CRPS, Hyperhydrosis Etc.
Interventions: PROCEDURE: lumbar sympathetic ganglion block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Mycophenolate Mofetil 250 mg Capsule Under Fasting Condition
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Mycophenolate Mofetil Capsule 250 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Study in Adolescents/Adults to Evaluate the Persistence up to 3.5 Yrs of GSK Biologicals Meningococcal Vaccine 134612
Status: COMPLETED
Conditions: Infections, Meningococcal
Interventions: BIOLOGICAL: Meningococcal vaccine 134612|BIOLOGICAL: Mencevax™ ACWY
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effects of Human Endotoxemia on Functional Capacity of Hematopoietic Stem and Progenitor Cells
Status: COMPLETED
Conditions: Sepsis, Endotoxemia, Immunosuppression
Interventions: DRUG: LPS|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Piedmont Aging, Cognition & Exercise Study-2
Status: COMPLETED
Conditions: Mild Cognitive Impairment|Prediabetes
Interventions: BEHAVIORAL: Exercise/Aerobic|BEHAVIORAL: Exercise/Stretching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Mint Tea for the Treatment of Nasal Polyps
Status: COMPLETED
Conditions: Nasal Polyps
Interventions: OTHER: Mint tea high in rosmarinic acid|OTHER: Mint tea low in rosmarinic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intravesical Antifibrinolytic for Patients With Hematuria and Clot Retention
Status: COMPLETED
Conditions: Urologic Diseases|Prostate Cancer|Bladder Cancer|Urinary Retention|Hematuria|Nurse Physician Relations|Nurse's Role|Patient Satisfaction
Interventions: DRUG: Tranexamic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of TRC105 in Combination With Paclitaxel/Carboplatin and Bevacizumab in Non-Squamous Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DRUG: TRC105
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Short Messaging Service Program to Help Quit Smoking During Perioperative Period.
Status: COMPLETED
Conditions: Tobacco Use Cessation|Perioperative/Postoperative Complications|Tobacco Smoking
Interventions: BEHAVIORAL: Brief behavioral intervention|OTHER: SMS Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Efficacy and Safety Study of Adjunctive Troriluzole in Obsessive Compulsive Disorder
Status: RECRUITING
Conditions: Obsessive-Compulsive Disorder
Interventions: DRUG: Troriluzole|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nylon Versus Polyurethane Epidural Catheters In Patients Undergoing Major Orthopedic Surgery
Status: RECRUITING
Conditions: Epidural; Anesthesia|Catheter Complications|Catheter Blockage|Catheter Dysfunction|Catheter Breakage
Interventions: DEVICE: Nylon (Polyamide) Epidural Catheter|DEVICE: Polyurethane Epidural Catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: the Possible Effect of the Antiviral Inhibitors for Treatment of Hepatitis C Virus Infection in Cardiac Function
Status: UNKNOWN
Conditions: Hepatitis
Interventions: PROCEDURE: Systolic function by echocardiography|PROCEDURE: Diastolic function by echocardiography
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Evaluate the Safety and Pharmacokinetics of Two Formulations of C1-esterase Inhibitor
Status: COMPLETED
Conditions: Hereditary Angioedema Types I and II
Interventions: BIOLOGICAL: Berinert|BIOLOGICAL: CSL830
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effect of Injectable Platelet Rich Fibrin on Stability of Dental Implant for Narrow Ridges
Status: UNKNOWN
Conditions: Dental Implantation, Endosseous
Interventions: PROCEDURE: study group|PROCEDURE: control group
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pembrolizumab With or Without Maintenance Sacituzumab Tirumotecan (Sac-TMT; MK-2870) in Metastatic Squamous Non-small Cell Lung Cancer (NSCLC) [MK-2870-023]
Status: RECRUITING
Conditions: Non-small Cell Lung Cancer|NSCLC
Interventions: BIOLOGICAL: Pembrolizumab|BIOLOGICAL: sac-TMT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Ibuprofen And Indomethacin For The Treatment Of The Patent Ductus Arteriosus in Very Premature Babies
Status: WITHDRAWN
Conditions: Ductus Arteriosus, Patent|Very Low Birth Weight Infants
Interventions: DRUG: Ibuprofen|DRUG: Indomethacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diagnostic Accuracy of Gallium-68-DOTATATE PET/CT Compared to Indium-111-pentetreotide Scintigraphy (SPECT/CT) for Gastroenteropancreatic Neuroendocrine Tumors
Status: TERMINATED
Conditions: Gastroenteropancreatic Neuroendocrine Tumors
Interventions: DRUG: Gallium-68-DOTATATE PET/CT (index test)|DRUG: Indium-111-Octreoscan (standard test)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study on Evaluating the Safety of HST101 in Healthy Chinese Participants
Status: NOT_YET_RECRUITING
Conditions: Hypercholesterolemia|Hyperlipidemias|Dyslipidemias|Lipid Metabolism Disorders|Metabolic Diseases
Interventions: DRUG: HST101
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bilateral vs. Unilateral Stimulation in Neurological Bladder Disroders
Status: UNKNOWN
Conditions: Neurogenic Urinary Bladder, Spastic
Interventions: PROCEDURE: urostim bilateral|PROCEDURE: urostim unilateral
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improving Survey Procedures for Young Men Who Have Sex With Men in Web-based HIV Prevention: Retention Study
Status: COMPLETED
Conditions: Healthy
Interventions: BEHAVIORAL: Monetary Incentive|BEHAVIORAL: Altruistic Incentive|BEHAVIORAL: Dashboard Incentive
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Assessment of Ventilation-perfusion Abnormalities in Patients With Stable Smoking-related Airways Disease
Status: TERMINATED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: salbutamol + ipratropium bromide nebules|DRUG: nebulized saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Oophorectomy Followed by Chemotherapy Versus Chemotherapy Alone in Colorectal Cancer Patients
Status: COMPLETED
Conditions: Stage IV Colon Cancer
Interventions: PROCEDURE: Oophrectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Yoga-based Exercises of Healthcare Workers During COVID-19 Pandemic: Prospective Clinical Trial
Status: COMPLETED
Conditions: COVID-19 Pandemic|Yoga|Exercise Therapy|Mind-Body Therapies|Muscle Stretching Exercises
Interventions: OTHER: yoga-based exercises therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Compare the Effect of DPP-IV Inhibitor or TZD on Glycemic Variability and Oxidative Stress in Patient With 2 Diabetes
Status: UNKNOWN
Conditions: Diabetes Mellitus|Oxidative Stress
Interventions: DRUG: Galvus (vildagliptin)|DRUG: pioglitazone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Daily vs Alternate Day Iron Supplementation for Pregnant Women With Iron Deficiency Anemia
Status: COMPLETED
Conditions: Iron Deficiency Anemia
Interventions: DIETARY_SUPPLEMENT: Ferrous Sulfate|DIETARY_SUPPLEMENT: Ferrous Sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cartomerge Versus NavX Fusion in Catheter Ablation of Atrial Fibrillation
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: PROCEDURE: NavX Fusion|PROCEDURE: Cartomerge
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reduction of Triglycerides in Women on Hormone Replacement Therapy
Status: COMPLETED
Conditions: Cardiovascular Diseases|Atherosclerosis|Postmenopause|Heart Diseases
Interventions: BEHAVIORAL: Diet, fat-restricted|BEHAVIORAL: Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study Comparing a Plant-Based Diet With Supplements and Placebo in People With Monoclonal Gammopathy of Undetermined Significance (MGUS) or Smoldering Multiple Myeloma (SMM)
Status: RECRUITING
Conditions: Multiple Myeloma|Monoclonal Gammopathy of Undetermined Significance
Interventions: OTHER: Whole Foods Plant-based Diet|DIETARY_SUPPLEMENT: Algae omega 3|OTHER: Placebo supplements
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of Fermented Ginseng Powder on Liver Function
Status: COMPLETED
Conditions: Fatty Liver, Nonalcoholic
Interventions: DIETARY_SUPPLEMENT: fermented ginseng powder|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Comparative Study of SPARC's SDP-133 Once Daily and Lumigan in Subjects With Open Angle Glaucoma or Ocular Hypertension
Status: WITHDRAWN
Conditions: Open Angle Glaucoma|Ocular Hypertension
Interventions: DRUG: SDP-133|DRUG: Lumigan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Exercise Type on Muscle Quality in Patients With OA, SARC and RA: an Explorative Study
Status: NOT_YET_RECRUITING
Conditions: Rheumatoid Arthritis|Osteoarthritis|Sarcopenia
Interventions: OTHER: High load exercise type|BEHAVIORAL: Low load exercise type
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: MAGE-C2 TCR T Cell Trial to Treat Melanoma and Head and Neck Cancer
Status: RECRUITING
Conditions: Melanoma|Melanoma, Uveal|Head and Neck Cancer
Interventions: BIOLOGICAL: Adoptive therapy with autologous MC2 TCR T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Using a Mobile Application as a Support at the Prescription of Appropriate Medications for Elderly
Status: COMPLETED
Conditions: Inappropriate Prescribing
Interventions: OTHER: Use of an application to for mobile devices like decision-making support for prescription drugs to elderly patients
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: S9333A Study of Blood and Bone Marrow Samples From Patients With Previously Untreated Primary Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Leukemia
Interventions: GENETIC: polyacrylamide gel electrophoresis|GENETIC: western blotting|OTHER: immunologic technique|OTHER: laboratory biomarker analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Insertion of an Intrauterine Device (IUD) After Medical Abortion
Status: COMPLETED
Conditions: Intrauterine Device Expulsion|Medical Abortion|Induced Abortion
Interventions: DEVICE: IUD insertion [Copper T-380A or Levonorgestrel (intrauterine system) IUS]
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CKD-828 Drug Interaction Study (S-amlodipine)
Status: COMPLETED
Conditions: Healthy Male Volunteers
Interventions: DRUG: S-amlodipine 5mg,Telmisartan 80mg|DRUG: S-amlodipine 5mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Minimally Invasive Root Canal Treatment With Active Disinfection on Single Rooted Teeth With Periapical Lesions
Status: COMPLETED
Conditions: Radiographic Healing of Periapical Lesions Following Ultrasonic Activation of Heated Sodium Hypochlorite Without Instrumentation of Root Canals
Interventions: PROCEDURE: non-instrumented root canal treatment with passive ultrasonic activation of heated sodium hypochlorite|PROCEDURE: conventional root canal treatment with passive ultrasonic activation of heated sodium hypochlorite
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Stem Cell Study for Patients With Leg Ulcer/Gangrene
Status: COMPLETED
Conditions: Leg Pain|Ulcer|Gangrene|Ischemia|Peripheral Vascular Diseases
Interventions: GENETIC: Autologous peripheral blood CD34 positive cell therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Physiological Effect of Ataulfo Mango (Manguifera Indica) Beverage in Exercise
Status: COMPLETED
Conditions: Exercise-induced Oxidative Stress
Interventions: DIETARY_SUPPLEMENT: Mango pulp beverage|DIETARY_SUPPLEMENT: Mango pulp and peel beverage|DIETARY_SUPPLEMENT: Control beverage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Combined Ranibizumab and Iluvien for Diabetic Macular Oedema
Status: WITHDRAWN
Conditions: Diabetic Macular Edema|Diabetes
Interventions: DRUG: Iluvien 0.19 MG Drug Implant|DRUG: Ranibizumab Injection [Lucentis]|PROCEDURE: Sham Intravitreal Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Microcirculation Recruitment Using Albumin 20% and Terlipressin in Septic Patients
Status: UNKNOWN
Conditions: Septic Shock
Interventions: DRUG: Albumin 20% and terlipressin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Non Invasive Brain Stimulation for PTSD
Status: COMPLETED
Conditions: Posttraumatic Stress Disorder (PTSD)
Interventions: DEVICE: Active tDCS|DEVICE: Sham tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Consumption of a Novel Functional Yogurt on Blood Biomarkers of Healthy Participants
Status: ENROLLING_BY_INVITATION
Conditions: Healthy
Interventions: OTHER: Consumption of a meal with yogurt enriched with probiotics immobilized on oat flakes and polyphenols|OTHER: Consumption of a meal with yogurt enriched with probiotics immobilized on oat flakes|OTHER: Consumption of a meal with plain Yogurt with oat flakes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study of Photodynamic Therapy (PDT) Using HPPH in Barrett's Esophagus
Status: COMPLETED
Conditions: Barrett's Esophagus|CIS|High Grade Dysplasia
Interventions: DRUG: HPPH
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radioimmunotherapy With 131I-L19SIP in Patients With Cancer
Status: TERMINATED
Conditions: Patients With Cancer
Interventions: DRUG: 131I-L19SIP Radioimmunotherapy (RIT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Probiotics in Immune System of Healthy Adults
Status: COMPLETED
Conditions: Conditions Influencing Health Status
Interventions: OTHER: Probiotic CNCM I-4034|OTHER: Probiotic CNCM I-4035|OTHER: Probiotic CNCM I-4036|OTHER: Probiotics CNCM I-4035 and CNCM I-4036|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: A Comparison Between Two Educational Methods in the Rehabilitation of the Microstomia in Systemic Sclerosis
Status: COMPLETED
Conditions: Scleroderma, Systemic
Interventions: BEHAVIORAL: Brochure and DVD plus nursing training|BEHAVIORAL: Brochure and DVD only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Toxicities Associated With Subcutaneous Administration of Ethyol (Amifostine) for the Prevention of Radiation-Induced Toxicities
Status: COMPLETED
Conditions: Head and Neck Cancer|Lung Cancer
Interventions: DRUG: Ethyol (Amifostine)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Granisetron Transdermal Patch for Prophylaxis of Nausea and Vomiting in Patients Receiving Oral Anticancer Agents
Status: UNKNOWN
Conditions: Chemotherapy-induced Nausea and Vomiting (CINV)
Interventions: DRUG: Granisetron Transdermal Delivery System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT