pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: PatientSpot Formerly Known as ArthritisPower
Status: RECRUITING
Conditions: Rheumatoid Arthritis|Ankylosing Spondylitis|Fibromyalgia|Gout|Crohn Disease|Juvenile Idiopathic Arthritis|Lupus Erythematosus|Myositis|Osteoarthritis|Osteoporosis|Psoriasis|Psoriatic Arthritis|Scleroderma|Dermatomyositis|Inflammatory Bowel Diseases|Polymyositis|Axial Spondyloarthritis|Diffuse Idiopathic Skeletal Hyperostosis|Polymyalgia Rheumatica|Giant Cell Arteritis|Temporal Arteritis|Wegener|Relapsing Polychondritis|Undifferentiated Connective Tissue Disease|Spinal Cord Injuries|Alzheimer Disease|Amyotrophic Lateral Sclerosis|Ataxia|Bell Palsy|Brain Tumor|Cerebral Aneurysm|Epilepsy|Guillain-Barre Syndrome|Headache|Head Injury|Hydrocephalus|Lumbar Disc Disease|Meningitis|Multiple Sclerosis|Muscular Dystrophy|Neurocutaneous Syndromes|Parkinson Disease|Stroke|Cluster Headache|Tension-Type Headache|Chronic Obstructive Pulmonary Disease|Asthma|Lung Cancer|Cystic Fibrosis|Sleep Apnea|Eczema|Alopecia|Chronic Inflammation|Unstable Angina|Heart Attack|Heart Failure|Arrythmia|Valve Heart Disease|High Blood Pressure|Congenital Heart Disease|Peripheral Arterial Disease|Diabetes|Chronic Liver Disease|Obesity
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Tolerability of ABM-1310 in Patients With Advanced Solid Tumors
Status: TERMINATED
Conditions: Advanced Solid Tumor|BRAF V600 Mutation
Interventions: DRUG: ABM-1310|DRUG: Cobimetinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Role of Angiotensin Type I Receptor in the Regulation of Human Peripheral Vascular Function
Status: COMPLETED
Conditions: Atherosclerosis|Heart Failure, Congestive|Hypertension|Myocardial Infarction
Interventions: DRUG: Angiotensin II type 1 receptor antagonists
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Filgotinib Alone and in Combination With Methotrexate (MTX) in Adults With Moderately to Severely Active Rheumatoid Arthritis Who Are Naive to MTX Therapy
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Filgotinib|DRUG: Placebo to match filgotinib|DRUG: MTX|DRUG: Placebo to match MTX
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing Intravenous Magnesium Sulfate With Dexamethasone as Adjuvants to Ultrasound Guided TAPblock
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: PROCEDURE: Ultrasound guided transversus abdominis plane block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: A Study of LY3819253 (LY-CoV555) in Participants Hospitalized for COVID-19
Status: COMPLETED
Conditions: COVID-19
Interventions: DRUG: LY3819253|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Knee Split Comparison After ACL Reconstruction
Status: RECRUITING
Conditions: ACL Tear|Arthrofibrosis|ACL Injury
Interventions: DEVICE: Graymont X ERIS Knee Splint|DEVICE: Standard Hinge Knee Brace
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Trial of Prognostic Factors and Surgical Methods for the Treatment of Idiopathic Macular Holes
Status: COMPLETED
Conditions: Idiopathic Macular Hole
Interventions: PROCEDURE: macular hole operation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: L. Casei DG® in Patients With Irritable Bowel Syndrome.
Status: COMPLETED
Conditions: IBS - Irritable Bowel Syndrome
Interventions: DIETARY_SUPPLEMENT: L.casei DG|DIETARY_SUPPLEMENT: PLACEBO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Virtual Planning of ALT Flap
Status: WITHDRAWN
Conditions: Tongue SCC
Interventions: PROCEDURE: ALTF (Anterolateral thigh flap) with preoperative virtual planning|PROCEDURE: ALTF (Anterolateral thigh flap) with conventional method
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Namenda on Short Term Memory and Attention in Patients With Mild to Moderate Traumatic Brain Injury
Status: TERMINATED
Conditions: Traumatic Brain Injury
Interventions: DRUG: Memantine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Engaging Motivation for the Prevention of Weight Regain
Status: COMPLETED
Conditions: Obesity
Interventions: BEHAVIORAL: Mindfulness Based Weight Loss Maintenance (MBWLM)|BEHAVIORAL: Behavioral: Standard Behavioral Weight-Loss Maintenence
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ublituximab + Ibrutinib in Select B-cell Malignancies
Status: COMPLETED
Conditions: Chronic Lymphocytic Leukemia|Mantle Cell Lymphoma
Interventions: DRUG: Ublituximab|DRUG: Ibrutinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pemetrexed Disodium and Docetaxel in Treating Patients With Advanced Solid Tumors
Status: COMPLETED
Conditions: Breast Cancer|Esophageal Cancer|Gastric Cancer|Head and Neck Cancer|Lung Cancer|Ovarian Cancer|Prostate Cancer
Interventions: DRUG: Taxotere (Docetaxel)|DRUG: Alimta (Pemetrexed)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Limb-Girdle Muscular Dystrophy Type 2I in Norway
Status: ACTIVE_NOT_RECRUITING
Conditions: Limb Girdle Muscular Dystrophy, Type 2I|Limb Girdle Muscular Dystrophy|Muscular Dystrophies|Limb Girdle Muscular Dystrophy R9 FKRP-related
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Role of Neuroactive Steroids in Stress, Alcohol Craving and Alcohol Use in Alcohol Use Disorders
Status: COMPLETED
Conditions: Alcohol Use Disorder
Interventions: DRUG: Pregnenolone300|DRUG: Pregnenolone500|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cognitive Activation Therapy for MCI: A Randomized Control Study
Status: UNKNOWN
Conditions: Mild Cognitive Impairment
Interventions: BEHAVIORAL: Cogntive Activation Training|BEHAVIORAL: Waitlist Control / Home-based training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Analysis of PD-L1, TMB, MSI and ctDNA Dynamics to Predict and Monitor Response to Immunotherapy in Metastatic Cancer.
Status: RECRUITING
Conditions: Non Small Cell Lung Cancer|Breast Cancer|Colorectal Cancer|Gastric Cancer|Liver Cancer|Advanced Cancer|Immune Checkpoint Inhibitor
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety, Tolerability and Pharmacokinetics of AD16 Tablets in Adult Healthy Subjects After Single Administration
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: AD16 5mg、10mg、20mg、30mg、40mg、60mg、80mg|DRUG: AD16 placebo 5mg、10mg、20mg、30mg、40mg、60mg、80mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Open-Label Extension (OLE) Study for Safety and Efficacy of Velneperit (S-2367) in Obese Subjects
Status: COMPLETED
Conditions: Obesity
Interventions: DRUG: S-2367 (velneperit)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: UNification of Treatments and Interventions for TInnitus Patients - Randomized Clinical Trial (UNITI-RCT)
Status: COMPLETED
Conditions: Tinnitus
Interventions: OTHER: Structured counseling|DEVICE: Hearing aids|OTHER: Cognitive behavioral therapy|OTHER: Sound therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of Kanglaite Injection (KLTi) in Advanced Non-Small Cell Lung Cancer (NSCLC)
Status: UNKNOWN
Conditions: NSCLC
Interventions: DRUG: Kanglaite Injection+Chemotherapy|DRUG: Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Suramin and Paclitaxel in Treating Women With Stage IIIB-IV Breast Cancer
Status: COMPLETED
Conditions: Recurrent Breast Cancer|Stage IIIB Breast Cancer|Stage IV Breast Cancer
Interventions: DRUG: suramin|DRUG: paclitaxel|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Placebo- Controlled Study to Evaluate the Safety and Immunogenicity of the RSV-F Vaccine in Elderly Adults
Status: COMPLETED
Conditions: Respiratory Syncytial Virus (RSV)
Interventions: BIOLOGICAL: RSV-F Vaccine|BIOLOGICAL: Saline Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Interest of Using an Electric Wheelchair Equipped With Anti-collision Sensors for Elderly People in EHPAD
Status: TERMINATED
Conditions: Elderly
Interventions: DEVICE: Using anti-collision Sensors on electric wheelchairs|OTHER: Use of an electric wheelchair without sensors
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of Capsaicin Patch for the Management of Peripheral Neuropathic Pain
Status: COMPLETED
Conditions: Peripheral Nerve Injury|Postherpetic Neuralgia
Interventions: DRUG: CAPNP, 50 ug/cm2 capsaicin patch|DRUG: CAPNP, 100 ug/cm2 capsaicin patch|DRUG: 0.075% capsaicin cream|OTHER: Placebo patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Mechanisms of Obesity and Its Metabolic Complications in Youth
Status: RECRUITING
Conditions: Obesity, Childhood
Interventions: DIETARY_SUPPLEMENT: obese carbohydrate diet|DIETARY_SUPPLEMENT: lean carbohydrate diet
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Scapular Muscle Training in Improving Grip Strength Among Lateral Epicondylitis Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Lateral Epicondylitis
Interventions: DIAGNOSTIC_TEST: Left/ Right affected arm|OTHER: Grip strength
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Efficacy of Gentamicin Topical Gel (AppliGel-G) for Treatment of Mild to Moderately Infected Diabetic Foot Ulcers
Status: TERMINATED
Conditions: Diabetic Foot Ulcers
Interventions: DRUG: Gentamicin Topical Gel|DRUG: Ciprofloxacin|DRUG: Doxycycline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Top Down Versus Step up in Pediatric Ulcerative Colitis
Status: RECRUITING
Conditions: Ulcerative Colitis|Infliximab|Children
Interventions: DRUG: Infliximab|DRUG: Corticosteroids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Radiosurgery With or Without Whole-Brain Radiation Therapy in Treating Patients With Brain Metastases
Status: COMPLETED
Conditions: Metastatic Cancer
Interventions: RADIATION: radiation therapy|PROCEDURE: surgery|RADIATION: WBRT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Trial Comparing Performance of Molecular Markers for Indeterminate Thyroid Nodules
Status: ACTIVE_NOT_RECRUITING
Conditions: Thyroid
Interventions: OTHER: Afirma GEC|OTHER: ThyroSeq v.2|OTHER: Afirma GSC|OTHER: ThyroSeq v.3
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: International Multicenter Project Comparing Radiofrequency Ablation Versus Implantable Defibrillator After Well-tolerated Ventricular Tachycardia in Ischemic Heart Disease With Minimally Impaired Ejection Fraction
Status: NOT_YET_RECRUITING
Conditions: Ischemic Heart Disease|Ventricular Tachycardia
Interventions: OTHER: Adverse events collection|OTHER: Quality of life questionnaire EQ-5D-5L|OTHER: Medical-economic evaluation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Radical Radiotherapy and Chemotherapy Combined With Maintenance Chemotherapy in the Treatment of Stage N3 NPC
Status: UNKNOWN
Conditions: Nasopharyngeal Carcinoma
Interventions: DRUG: Capecitabine/Tiggio
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use Surveillance Technology to Reduce Elder Abuse Recidivism
Status: TERMINATED
Conditions: Elder Abuse|Self Neglect|Aging|Domestic Abuse
Interventions: BEHAVIORAL: Surveillance camera(s)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: RCT for Electroconvulsive Treatment Followed by Cognitive Control Training
Status: COMPLETED
Conditions: Depressive Episode|Electroconvulsive Therapy|Cognitive Remediation
Interventions: BEHAVIORAL: Cognitive Control Training|BEHAVIORAL: Active Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Biocompatibility Evaluation of Contact Lens Coatings
Status: COMPLETED
Conditions: Refractive Errors|Ametropia
Interventions: DEVICE: Contact lens with investigational coating 1|DEVICE: Balafilcon A contact lens|DEVICE: OPTI-FREE® RepleniSH® MPDS|DEVICE: Contact lens with investigational coating 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bone Marrow Aspirate Concentrate (BMAC) Treatment for Knee Osteoarthritis
Status: NOT_YET_RECRUITING
Conditions: Knee Osteoarthritis|Musculoskeletal Diseases
Interventions: BIOLOGICAL: Autologous Bone Marrow Aspirate Concentrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Selective TrkA Inhibitor VMD-928 to Treat TrkA Overexpression Driven Solid Tumors or Lymphoma
Status: RECRUITING
Conditions: Head and Neck Carcinoma|Adenoid Cystic Carcinoma|Lung Cancer|Non-Small Cell Lung Cancer|Breast Cancer|Pancreatic Cancer|Mesothelioma|Thymic Carcinoma|Cervical Cancer|Ovarian Cancer|Bladder Cancer|Esophageal Cancer|Uterine Cancer|Sarcoma|Any Solid Tumors Progressed After a Prior Immunotherapy
Interventions: DRUG: VMD-928 300 mg Tablet (ongoing); 100 mg Capsule (complete)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Incidence of Deep Vein Thrombosis at Doppler Echo in Covid-19 Patients With SARS-Cov-2 Pneumopathy Hospitalized in ICU
Status: COMPLETED
Conditions: Deep Vein Thrombosis
Interventions: OTHER: Doppler Echo
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy and Safety of Dupilumab in Participants ≥12 to <18 Years of Age, With Moderate-to-severe Atopic Dermatitis
Status: COMPLETED
Conditions: Moderate-to-Severe Atopic Dermatitis|Dermatitis, Dermatitis Atopic|Eczema, Skin Diseases, Skin|Diseases Genetic, Genetic|Diseases Inborn, Skin|Disease, Eczematous Skin|Hypersensitivity, Immediate|Hypersensitivity, Immune System Diseases|Dermatitis, Atopic
Interventions: DRUG: Dupilumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Orodispersible Minitablets of Enalapril in Children With Heart Failure Due to Dilated Cardiomyopathy
Status: UNKNOWN
Conditions: Heart Failure|Dilated Cardiomyopathy
Interventions: DRUG: Enalapril Orodispersible Minitablet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: OSIG-eye Drops Treatment for Dry Eye Disease
Status: WITHDRAWN
Conditions: Dry Eye
Interventions: DRUG: Ocular Surface Immune Globulin (OSIG)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Tobacco Smoke Exposure on Epigenetic Signatures and Immunotoxicological Reactions
Status: COMPLETED
Conditions: The Study Focused on Reducing Tobacco Smoke Exposure for Child.
Interventions: BEHAVIORAL: Tobacco smoke reduction trial intervention program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Changes in Tear Lipid Layer Thickness After Short Exposure to Light Emitting Diode Displays
Status: COMPLETED
Conditions: Lipid Tear Deficiency (Disorder)|Dry Eye Disease
Interventions: DEVICE: LED screen (InnoLux, Taiwan)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Evaluating the Efficacy of Perinatal Membrane Allografts for the Treatment of Diabetic Foot Ulcers.
Status: NOT_YET_RECRUITING
Conditions: Diabetic Foot Ulcer
Interventions: OTHER: Multilayer perinatal tissue allograft|OTHER: Full thickness perinatal tissue allograft|OTHER: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Everolimus Dose Finding Study for Stage IV or Recurrent Cervical Cancer
Status: WITHDRAWN
Conditions: Cervical Cancer
Interventions: DRUG: RAD001|DRUG: Cisplatin|RADIATION: External Beam Whole Pelvis Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rheumatoid Arthritis Extension Trial For Subjects Who Have Participated In Other PF-05280586 Trials (REFLECTIONS B328-04)
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: BIOLOGICAL: Rituximab-Pfizer (PF-05280586) x 3 courses|BIOLOGICAL: Rituximab-EU+ Rituximab-Pfizer x 2 Courses|BIOLOGICAL: Rituximab-US + Rituximab-Pfizer x 2 Courses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Oral IXAZOMIB in Combination With Lenalidomide and Dexamethasone in Participants With Newly Diagnosed Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Ixazomib|DRUG: Lenalidomide|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial Comparing Cosmetic Outcomes of Pediatric Laceration Closure Using Skin Glue, Medical Tape Versus Stitches
Status: TERMINATED
Conditions: Laceration
Interventions: PROCEDURE: Absorbable Sutures|PROCEDURE: Steri-Strips|PROCEDURE: Dermabond
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: To Determine the Minimum Amount of Alternaria Alternata Allergen Extract Producing a Positive Skin Reaction.
Status: COMPLETED
Conditions: Allergy to Alternaria Fungus
Interventions: BIOLOGICAL: four differente concentrations of Alternaria alternata allergen extract, positive control and negative control
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Aggrenox To Treat Acute Covid-19
Status: COMPLETED
Conditions: Covid19
Interventions: DRUG: Dipyridamole ER 200mg/ Aspirin 25mg orally/enterally AND Standard of care|OTHER: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Warm Water on GI System in Laparoscopic Cholecystectomy Patients
Status: COMPLETED
Conditions: Laparoscopic Cholecystectomy|Abdominal Distention
Interventions: OTHER: Drinking Warm Water Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: PF-06669571 In Subjects With Idiopathic Parkinson's Disease
Status: COMPLETED
Conditions: Idiopathic Parkinson's Disease
Interventions: DRUG: PF-06669571|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pharmacokinetics, Safety and Efficacy of POL7080 in Patients With Ventilator Associated Pseudomonas Aeruginosa Pneumonia
Status: COMPLETED
Conditions: Ventilator Associated Pneumonia|Lower Respiratory Infection
Interventions: DRUG: POL7080
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Identify Peripheral Biomarkers of Symptomatology, Neurocognitive Functions, and Medication Response in ADHD
Status: UNKNOWN
Conditions: Attention-deficit/Hyperactivity Disorder
Interventions: DRUG: Methylphenidate (Concerta)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating the Safety, Tolerability and Preliminary Efficacy of IBI322 in Subjects With Hematologic Malignancy
Status: UNKNOWN
Conditions: Hematologic Malignancy
Interventions: BIOLOGICAL: IBI322
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Rindopepimut/GM-CSF in Patients With Relapsed EGFRvIII-Positive Glioblastoma
Status: COMPLETED
Conditions: Glioblastoma|Small Cell Glioblastoma|Giant Cell Glioblastoma|Gliosarcoma|Glioblastoma With Oligodendroglial Component|Recurrent Glioblastoma|Relapsed Glioblastoma
Interventions: DRUG: Bevacizumab|DRUG: Rindopepimut (CDX-110) with GM-CSF|DRUG: KLH
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Renal Sympathetic Denervation and Potential Effects on Glucose Metabolism and Cardiovascular Risk-Factors
Status: COMPLETED
Conditions: Hypertension, Resistant to Conventional Therapy
Interventions: PROCEDURE: Renal sympathetic denervation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acute Neurological Complications and Neurodevelopmental Outcome in Children Undergoing Extracorporeal Membrane Oxygenation.
Status: COMPLETED
Conditions: Extra Corporeal Membrane Oxygenation
Interventions: OTHER: DENVER scale (under 2 years old) or Pediatric Cerebral Performance Category (PCPC) score (over 2 years old)|OTHER: Pediatric Quality of Life Inventory™ (PedsQL)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Bacterial Decolonization to Prevent Radiation Dermatitis
Status: COMPLETED
Conditions: Radiation Dermatitis
Interventions: DRUG: Chlorhexidine gluconate solution|DRUG: Mupirocin Ointment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Va-Sense - Bacterial Vaginosis Once A Week Screening And Treatment To Reduce Infective Complications, Abortion And Preterm Delivery In Pregnant Women With Previous Preterm Delivery
Status: UNKNOWN
Conditions: Vaginal Infections|Bacterial Vaginosis|Late Miscarriage|Preterm Birth|Preterm Premature Rupture of Membranes
Interventions: DEVICE: VA-SENSE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Assisted Ambulation to Improve Health Outcomes for Older Medical Inpatients
Status: RECRUITING
Conditions: Mobility Limitation|Frailty|Hospital Acquired Condition|Weakness, Muscle
Interventions: BEHAVIORAL: Mobility technician
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Gel Nail Application on Pulse Oximetry Measurements in Healthy Individuals
Status: RECRUITING
Conditions: Healthy Individuals|Gel Nail|Oxygen Saturation|Nursing|Perioperative Care
Interventions: OTHER: Gel nail application
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Testing the Use of Combination Therapy in Adult Patients With Newly Diagnosed Multiple Myeloma, the EQUATE Trial
Status: RECRUITING
Conditions: Plasma Cell Myeloma|RISS Stage I Plasma Cell Myeloma|RISS Stage II Plasma Cell Myeloma
Interventions: DRUG: Bortezomib|BIOLOGICAL: Daratumumab and Hyaluronidase-fihj|DRUG: Dexamethasone|DRUG: Lenalidomide|OTHER: Quality-of-Life Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessing Physical Fitness in Cancer Patients With Cardiopulmonary Exercise Testing and Wearable Data Generation
Status: COMPLETED
Conditions: Malignant Solid Tumour|Hematologic Malignancies|Planned Hematopoietic Cell Transplantation
Interventions: OTHER: Physical performance testing and patient-generated health data
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Increasing Physical Activity in COPD Through Rhythmically Enhanced Music
Status: ACTIVE_NOT_RECRUITING
Conditions: COPD Patients and Patients Recovering From COVID19
Interventions: BEHAVIORAL: rhythmically auditory stimulation enhanced music|BEHAVIORAL: control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Basal Bolus Versus Basal Insulin in Type 2 Diabetes Mellitus (T2DM)
Status: COMPLETED
Conditions: Type 2 Diabetes|Hyperglycemia
Interventions: DRUG: sliding scale regular insulin (SSRI)|DRUG: Basal Bolus|DRUG: Basal Plus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study of 5-Fluorouracil Administered as a One Hour Infusion in Combination With Calcium Leucovorin and Interferon Alpha-2A in Advanced Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Neoplasms
Interventions: DRUG: 5-fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Venetoclax and Ibrutinib in Patients With Relapsed/Refractory CLL or SLL
Status: COMPLETED
Conditions: Recurrent Chronic Lymphocytic Leukemia|Recurrent Small Lymphocytic Lymphoma|Refractory Chronic Lymphocytic Leukemia|Refractory Small Lymphocytic Lymphoma
Interventions: DRUG: Ibrutinib|DRUG: Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Using an mHealth App to Transition Care of Type-1 Diabetes From Parents to Teens
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus|Adolescent Behavior|Parent-Child Relations|Communication
Interventions: DEVICE: MyT1DHero
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Investigating the Efficacy of Brain Octane® Oil on Cognition, Coordination, Reaction Time and Measurements of Physical Performance in Recreationally Active Adults
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Brain Octane Oil|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Effectiveness of VIRTUAL FIBROWALK STUDY
Status: UNKNOWN
Conditions: Fibromyalgia
Interventions: BEHAVIORAL: TAU + multicomponent treatment VIRTUAL FIBROWALK|BEHAVIORAL: Treatment as Usual (TAU)|BEHAVIORAL: TAU + Physiotherapy part of VIRTUAL FIBROWALK
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Disorder-tailored Transcranial Direct Current Stimulation (tDCS) of the Prefrontal Cortex
Status: UNKNOWN
Conditions: Major Depressive Disorder|Schizophrenia
Interventions: DEVICE: Transcranial direct current stimulation (tDCS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Trial of NS/GEMOX Chemotherapy in Patients With Untreated Pancreatic Cancer ( HZ-NS/GEMOX-PC )
Status: UNKNOWN
Conditions: Pancreatic Cancer
Interventions: DRUG: Albumin-bound paclitaxel|DRUG: S-1|DRUG: Oxaliplatin|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Safety and Cardiovascular Effects of Autologous Adipose-Derived Stromal Cells Implantation In Patients During the Acute Recovery Phase of ST-Elevation Myocardial Infarction
Status: WITHDRAWN
Conditions: Acute Myocardial Infarction
Interventions: PROCEDURE: ASC isolation and implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Platelet Rich Plasma (PRP) in Chronic Epicondylitis
Status: COMPLETED
Conditions: Epicondylitis
Interventions: DRUG: US-guided tenotomy with PRP|DRUG: US-guided tenotomy with lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy in iNPH Shunting (PENS) Trial
Status: RECRUITING
Conditions: Idiopathic Normal Pressure Hydrocephalus (INPH)
Interventions: DEVICE: programmable CSF shunt valve
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Exploration of Immunodynamic Monitoring in the Population Evaluation of Neoadjuvant Chemotherapy Immunotherapy in Patients With Solid Tumors of the Chest.
Status: UNKNOWN
Conditions: Non-small Cell Lung Cancer|Esophageal Squamous Cell Carcinoma
Interventions: DRUG: Anti-PD-1 antibody combined with Paclitaxel and carboplatin.|PROCEDURE: Surgical treatment stage
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Recovery Profiles of Remifentanil-based Regimen for Cardiac Surgery
Status: COMPLETED
Conditions: Cardiac Surgery
Interventions: DRUG: remifentanil-based|DRUG: sevoflurane-sufentanil balanced
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacogenetics, Emotional Reactivity and Smoking
Status: COMPLETED
Conditions: Tobacco Use Disorder|Smoking Cessation
Interventions: DRUG: Bupropion|DRUG: Varenicline|DRUG: Placebo|BEHAVIORAL: Smoking Cessation Counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: BG9924 in Combination With Methotrexate Extension of Study 104RA203 (NCT 00458861)
Status: TERMINATED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: BG9924
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low Intensity Shockwaves Therapy for the Treatment of Erectile Dysfunction. 12- Month Follow-Up
Status: TERMINATED
Conditions: Erectile Dysfunction
Interventions: DEVICE: Shockwave therapy|OTHER: Sham shockwave therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Telerehabilitation After Shoulder Arthroplasty
Status: ACTIVE_NOT_RECRUITING
Conditions: Arthritis Shoulder Glenohumoral Joint|Rotator Cuff Tear Arthropathy|Arthropathy Shoulder
Interventions: OTHER: Telerehabilitation; physical therapy via telecommunication device (i.e. online video conferencing)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immediate Release (IR) to Sustained Release (SR) Switching Study: Study of Switching From IR Seroquel to SR Seroquel in Outpatients With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Seroquel SR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Olaparib, Cediranib Maleate, and Standard Chemotherapy in Treating Patients With Small Cell Lung Cancer
Status: TERMINATED
Conditions: Extensive Stage Lung Small Cell Carcinoma
Interventions: DRUG: Carboplatin|DRUG: Cediranib|DRUG: Cediranib Maleate|DRUG: Cisplatin|DRUG: Etoposide|DRUG: Olaparib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Toripalimab or Placebo as Adjuvant Therapy in Hepatocellular Carcinoma After Radical Resection
Status: ACTIVE_NOT_RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: BIOLOGICAL: TORIPALIMAB INJECTION(JS001 )
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy, Bevacizumab, and/or Atezolizumab in Treating Patients With Deficient DNA Mismatch Repair Metastatic Colorectal Cancer, the COMMIT Study
Status: RECRUITING
Conditions: Metastatic Colorectal Adenocarcinoma|Stage IV Colorectal Cancer AJCC v7
Interventions: DRUG: Atezolizumab|BIOLOGICAL: Bevacizumab|PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|DRUG: Fluorouracil|DRUG: Leucovorin|PROCEDURE: Magnetic Resonance Imaging|DRUG: Oxaliplatin|PROCEDURE: Positron Emission Tomography|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Investigate Outcomes of Trifocal Toric IOL POD FT in Asian Eyes
Status: ACTIVE_NOT_RECRUITING
Conditions: Cataract|Lens Opacities|Presbyopia
Interventions: DEVICE: IOL implantation experimental
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pneumatic Medicine: A Transformative Treatment for Diabetic Peripheral Neuropathy
Status: UNKNOWN
Conditions: Diabetic Polyneuropathy
Interventions: DEVICE: Sham device|DEVICE: NormaTec PCD (Peristaltic Pulse PCD)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Identifying Biomarkers for Lung Cancer Using Tissue Samples From Patients With Lung Cancer and From Healthy Participants
Status: COMPLETED
Conditions: Lung Cancer
Interventions: GENETIC: comparative genomic hybridization|GENETIC: fluorescence in situ hybridization|GENETIC: gene expression analysis|GENETIC: microarray analysis|GENETIC: protein expression analysis|OTHER: immunohistochemistry staining method|OTHER: laboratory biomarker analysis|OTHER: matrix-assisted laser desorption/ionization time of flight mass spectrometry|OTHER: medical chart review|PROCEDURE: diagnostic bronchoscopy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of the Unconformity of the Hormonal Status of Metastatic Lesions During a First Relapse of Breast Cancer Initially Expressing Estrogen Receptors: a Pilot Study on the Interest of PET With FES
Status: RECRUITING
Conditions: FES TEP in Detection of Estrogen Receptors
Interventions: OTHER: FES PET
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Enteral Bovine Lactoferrin in Preterm Infants
Status: COMPLETED
Conditions: Neonatal Disease
Interventions: DIETARY_SUPPLEMENT: bovine lactoferrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Shifting Perspectives: Enhancing Outcomes in Anorexia Nervosa With CRT
Status: COMPLETED
Conditions: Anorexia Nervosa
Interventions: BEHAVIORAL: Cognitive Remediation Therapy|BEHAVIORAL: Family Based Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: HOme-Based Self-management and COgnitive Training CHanges Lives (HOBSCOTCH)-Parkinson's Disease (HOBSCOTCH-Parkinson's)
Status: RECRUITING
Conditions: Parkinson Disease|Cognitive Dysfunction|Memory Disorders
Interventions: BEHAVIORAL: HOme-Based Self-management and COgnitive Training CHanges lives (HOBSCOTCH)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study to Compare Liposomal Iron With Ferrous Ascorbate in the Treatment of Iron Deficiency Anemia in Children
Status: NOT_YET_RECRUITING
Conditions: Nutritional Anemia
Interventions: DRUG: Ferric Pyrophosphate Liposomal|DRUG: ferrous ascorbate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Subdissociative Dose Ketamine for Treatment of Acute Pain in Subjects With Chronic Pain
Status: COMPLETED
Conditions: Chronic Pain
Interventions: DRUG: Ketamine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment With Dasatinib in Patients With Acral Lentiginous, Mucosal, or Chronic Sun-damaged Melanoma
Status: TERMINATED
Conditions: Melanoma
Interventions: DRUG: Dasatinib|PROCEDURE: Surgical Resection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Evaluate the Possible Efficacy of Nifuroxazide in Patient With Ulcerative Colitis
Status: RECRUITING
Conditions: Inflammatory Bowel Diseases
Interventions: DRUG: Mesalamine|DRUG: Nifuroxazide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Decision-making of ctDNA in Patients With mCRC After Failure of First-line Treatment Containing Cetuximab - a Single-center, Phase II Clinical Study
Status: NOT_YET_RECRUITING
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: Cetuximab Ab; Bevacizumab; Vermofenib + cetuximab;Trastuzumab+lapatinib or trastuzumab+pertuzumab; others
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of GLP-1 Receptor Activation on Central Reward and Satiety in Obesity and Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus|Diabetes Mellitus, Type 2|Obesity
Interventions: DRUG: exenatide|DRUG: exenatide + exendin (9-39)|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: GePheRal: Clinical Validation of the Genotypic Diagnosis of Hiv-1 Resistance to Raltegravir by Parallel Analysis of the Genotype and Phenotype Profiles of Resistance
Status: UNKNOWN
Conditions: HIV-1 Infected Patients|Fold-change Resistance|Resistance Mutations
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of Lower Extremity Tissue Perfusion With Polarized Laser Light
Status: UNKNOWN
Conditions: Diabetic Ulcer|Perfusion
Interventions: DEVICE: TcPO2|DEVICE: Green laser (at 532nm) and a fast camera
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Intravenous Iron Supplement for Iron Deficiency in Patients With Severe Aortic Stenosis
Status: UNKNOWN
Conditions: Severe Aortic Stenosis|Iron-deficiency
Interventions: DRUG: Intravenous iron isomaltoside|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Vocal Cord Imaging Techniques After Thyroidectomy
Status: COMPLETED
Conditions: Thyroid Nodule
Interventions: DEVICE: direct laringoscopy|DEVICE: fiberoptic nasal laringoscopy|DEVICE: ultrasonograph
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: REtrospective Analysis on the Use of COvered Stents for the Treatment of the Dysfunctional Vascular Access
Status: UNKNOWN
Conditions: Study Focuses on the Use of Covered Stents (Stent Grafts) for the Treatment of Dysfunctional Vascular Access of Hemodialysis Patients
Interventions: DEVICE: Covered Stent placement
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase 1b Study of the Safety of REN001 in Patients With Fatty Acid Oxidation Disorders
Status: COMPLETED
Conditions: Fatty Acid Oxidation Disorders
Interventions: DRUG: Low Dose REN001|DRUG: High Dose REN001
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I Study of the Safety, Tolerance, and Pharmacokinetics of 9-[2-(Bispivaloyloxymethyl)Phosphonylmethoxyethyl]Adenine (Bis-POM PMEA; Adefovir Dipivoxil) in HIV-Infected Patients
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Adefovir dipivoxil
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Exploring Changes in COVID-19 Vaccination Intentions by Prompting Altruistic Motives Using a Video Intervention
Status: COMPLETED
Conditions: Vaccine Refusal
Interventions: BEHAVIORAL: Altruism Video|BEHAVIORAL: COVID-19 Informational Text
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Research on the Blood- Cooling - Toxin - Removing - Stasis - Dispersing Protocol Evaluation of Hench-schonlein Purpura
Status: UNKNOWN
Conditions: Purpura, Schoenlein-Henoch
Interventions: DRUG: Placebo|DRUG: "ziying" granules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of HBO Therapy on Muscular Insulin Resistence in Type 2 Diabetes
Status: COMPLETED
Conditions: Obesity|Non-insulin-dependent Diabetes Mellitus
Interventions: PROCEDURE: HBO therapy|PROCEDURE: Hyperbaric room air
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Inhaled Milrinone and Epoprostenol for the Prevention of Difficult Cardiac Pulmonary Bypass Separation
Status: NOT_YET_RECRUITING
Conditions: Right Heart Failure|Right Ventricular Dysfunction
Interventions: DRUG: Combined Epoprostenol Sodium & Milrinone|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study of rhBMP-2/ACS/Allograft Bone Dowel for Anterior Lumbar Interbody Fusion in Patients With Symptomatic Degenerative Disc Disease
Status: COMPLETED
Conditions: Degenerative Disc Disease
Interventions: DEVICE: rhBMP-2/ACS/allograft bone dowel|DEVICE: Autogenous bone/allograft bone dowel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Implementation of a Health System Intervention to Improve Quality of Cancer Care for Rural Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Cancer
Interventions: OTHER: Iowa Cancer Affiliate Network (ICAN)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: DigiPuR: Digitally Supported Psychotherapy and Reintegration
Status: ACTIVE_NOT_RECRUITING
Conditions: Mental Disorder in Childhood
Interventions: OTHER: Digital aftercare|OTHER: TAU
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT