pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Valproic Acid (Depakote[Registered Trademark]) to Treat Autoimmune Lymphoproliferative Syndrome (ALPS)
Status: COMPLETED
Conditions: ALPS|Hypersplenism|Lymphadenopathy
Interventions: DRUG: Valproic Acid|PROCEDURE: CT Scan|PROCEDURE: Blood Sample
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exercise and Pain in Non-Hispanic Blacks and Whites
Status: WITHDRAWN
Conditions: Pain, Acute|Pain, Neuropathic|Analgesia|Aerobic Exercise|Exercise Training
Interventions: OTHER: Aerobic Exercise Training|OTHER: Interval Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Post-Market Clinical Follow-Up Study on the Safety and Performance of Ennovate® Complex
Status: RECRUITING
Conditions: Hyperkyphosis|Hyperlordosis|Congenital Scoliosis|Neuromuscular Scoliosis|Idiopathic Scoliosis
Interventions: DEVICE: posterior stabilization for the cervical spine
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Butyrate Against Pediatric Obesity
Status: COMPLETED
Conditions: Obesity, Childhood
Interventions: DIETARY_SUPPLEMENT: butyrate|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Memantine to Treat Huntington's Disease
Status: COMPLETED
Conditions: Huntington's Disease
Interventions: DRUG: Memantine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Safety of GRF6021 Infusions in Subjects With Parkinson's Disease and Cognitive Impairment
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: DRUG: GRF6021|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess Electrocardiogram Results in Healthy Volunteers Receiving Canagliflozin (JNJ-28431754)
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Canagliflozin (JNJ-28431754)|DRUG: Placebo|DRUG: Moxifloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Continuous Spinal Anesthesia With Hypobaric Bupivacaine to Preserve Hemodynamics in Elderly
Status: UNKNOWN
Conditions: Hip Fracture|Hypotension
Interventions: PROCEDURE: continuous spinal anesthesia|DRUG: hypobaric bupivacaine|DRUG: isobaric bupivacaine|DRUG: ephedrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Relative Bioavailability Study of Alprazolam 3 mg Extended Release Tablets Under Non-fasting Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Alprazolam 3 mg Extended Release Tablets, single dose|DRUG: XANAX XR® 3 mg tablets, single dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Study of Decompensated Alcoholic Cirrhosis Treatment by Stem Cells
Status: RECRUITING
Conditions: Alcoholic Cirrhosis
Interventions: BIOLOGICAL: Conventional therapy plus low dose UCMSCs treatment|BIOLOGICAL: Conventional therapy plus medium dose UCMSCs treatment|BIOLOGICAL: Conventional therapy plus high dose UCMSCs treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Correlation of FeNO, Blood Eosinophils, Bronchoalveolar Lavage Findings and Bronchial Epithelium Histopathology in Patients With Chronic Obstructive Pulmonary Disease and Asthma
Status: TERMINATED
Conditions: Obstructive Lung Diseases
Interventions: DIAGNOSTIC_TEST: Blood sampling, FeNO, bronchoalveolar lavage, bronchoscopic tissue sampling
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Staged Phase I/II Hepatitis C Prophylactic Vaccine
Status: COMPLETED
Conditions: Hepatitis C
Interventions: BIOLOGICAL: AdCh3NSmut1|BIOLOGICAL: MVA-NSmut|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Acute Minocycline Administration on Emotional Processing and Cognition in Healthy Volunteers
Status: COMPLETED
Conditions: Mood|Cognitive Change
Interventions: DRUG: Minocycline|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: GUIDEX® Versus Launcher™ Guiding Catheter in Percutaneous Coronary Intervention (PCI) (GUIDEX_FR)
Status: NOT_YET_RECRUITING
Conditions: Coronary Artery Disease
Interventions: DEVICE: GUIDEX® guiding catheter|DEVICE: Launcher™ coronary guide catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Mapping the 'Sweet Brain' in Healthy Participants
Status: COMPLETED
Conditions: Obesity|Sweeteners
Interventions: DIETARY_SUPPLEMENT: Stevia|DIETARY_SUPPLEMENT: Glucose|DIETARY_SUPPLEMENT: Maltodextrin|DIETARY_SUPPLEMENT: Water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Early Intervention to Promote Return to Work for People With Spinal Cord Injury
Status: NOT_YET_RECRUITING
Conditions: Spinal Cord Injuries|Spinal Cord Diseases
Interventions: OTHER: State Counselor-Coordinated Services|OTHER: Center Facilitator-Coordinated Services
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety & Immunogenicity of JNJ-64041809, a Live Attenuated Double-deleted Listeria Immunotherapy, in Participants With Metastatic Castration-resistant Prostate Cancer
Status: COMPLETED
Conditions: Prostatic Neoplasms, Castration-Resistant
Interventions: BIOLOGICAL: JNJ-64041809 (Cohort 1A and 1B)|BIOLOGICAL: JNJ-64041809 (Cohort 2A and 2B)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Anemia and Neutropenia in HIV/HCV Coinfected Patients Treated With Pegylated Interferon and Ribavirin
Status: TERMINATED
Conditions: Anemia|Neutropenia|Hepatitis C Virus|HIV Infections
Interventions: DRUG: erythropoietin, GCSF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Impact of Omeprazole on the Pharmacokinetics of Sotorasib Co-administered With an Acidic Beverage in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Omeprazole|DRUG: Sotorasib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of Tirzepatide (LY3298176) in Participants With Heart Failure With Preserved Ejection Fraction (HFpEF) and Obesity: The SUMMIT Trial
Status: COMPLETED
Conditions: Obesity|Heart Failure With Preserved Ejection Fraction (HFpEF)
Interventions: DRUG: Tirzepatide|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Influence of Cerebral Oedema in Intracerebral Haemorrhage
Status: NOT_YET_RECRUITING
Conditions: Stroke|Intra Cerebral Hemorrhage
Interventions: RADIATION: Brain MRI|BIOLOGICAL: Biological biomarkers
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: IBR900 Cell Injection Combined With Lenvatinib or Bevacizumab in the Treatment of Advanced Primary Liver Cancer
Status: UNKNOWN
Conditions: Advanced Primary Liver Cancer
Interventions: COMBINATION_PRODUCT: IBR900 combined with Lenvatinib|COMBINATION_PRODUCT: IBR900 combined with Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cytokine Induced Killer Cells as Post-Transplant Immunotherapy Following Allogeneic Hematopoietic Cell Transplantation
Status: UNKNOWN
Conditions: Multiple Myeloma|Blood and Marrow Transplant (BMT)
Interventions: DRUG: Cytokine Induced Killer Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Netarsudil for Acceleration of Corneal Endothelial Restoration
Status: TERMINATED
Conditions: Fuchs' Endothelial Dystrophy
Interventions: DRUG: Netarsudil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prevention of Ulinastatin on Acute Respiratory Distress Syndrome (ARDS)
Status: COMPLETED
Conditions: Acute Respiratory Distress Syndrome|Critical Illness
Interventions: DRUG: Ulinastatin|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pemetrexed, Cisplatin, and Radiation Therapy in Treating Patients With Esophageal or Gastroesophageal Junction Cancer
Status: COMPLETED
Conditions: Esophageal Cancer
Interventions: DRUG: cisplatin|DRUG: Pemetrexed|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dual and Single Switching Monopolar RFA Using Separable Clustered Electrode for Treatment of HCC
Status: COMPLETED
Conditions: Hepatocellular Carcinoma
Interventions: DEVICE: DSM|DEVICE: SSM|DEVICE: Separable clustered electrodes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Short-term Effects of TOLCAPONE on Transthyretin Stability in Subjects With Leptomeningeal TTR Amyloidosis (ATTR)
Status: COMPLETED
Conditions: Transthyretin Amyloidosis|Amyloidosis, Leptomeningeal, Transthyretin-Related
Interventions: DRUG: Tolcapone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Back Pain Using Transcutaneous Magnetic Stimulation (TCMS)
Status: COMPLETED
Conditions: Lower Back Pain
Interventions: DEVICE: Fischell Transcutaneous Magnetic Stimulation Pain Treatment Device|DEVICE: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Individualisation of Voriconazole Antifungal Therapy Antifungal Therapy
Status: SUSPENDED
Conditions: Immunocompromised Patient|Aspergillosis|Fusarium
Interventions: DRUG: VFEND
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Airway Peak Pressure-directed Laryngeal Mask Airway Intracuff Pressure Setting
Status: COMPLETED
Conditions: Laryngeal Mask Airway
Interventions: PROCEDURE: Airway peak pressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Goal-Directed Fluid Therapy in Patients Undergoing Lower Limb Surgeries
Status: NOT_YET_RECRUITING
Conditions: Anesthesia|ERAS|Fluid Overload|Hypovolemia; Surgical Shock
Interventions: PROCEDURE: Goal-Directed Fluid Therapy guided by Inferior Vena Cava Collapsibility Index|PROCEDURE: standard fluid management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Investigate the Pharmacokinetics of a Combined Oral Contraceptive When Given Alone and in Combination With GSK3036656 in Female Participants of Non-childbearing Potential Aged 18 to 65 Years of Age
Status: RECRUITING
Conditions: Tuberculosis
Interventions: DRUG: EE/LNG|DRUG: GSK3036656 Dose Level 1|DRUG: GSK3036656 Dose Level 2
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of the Absorption, Metabolism, and Excretion of [14C]-Brensocatib Following a Single Oral Administration in Healthy Male Participants
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: [14C]-brensocatib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Anterior Approach (Deltopectoral) and Lateral Approach (Deltoid Splitting) in Shoulder Reverse Arthroplasty for Proximal Humerus Fracture
Status: UNKNOWN
Conditions: Humeral Fracture|Aged Patient|Reversed Total Shoulder Arthroplasty|Surgical Approach
Interventions: PROCEDURE: Reversed total shoulder arthroplasty|PROCEDURE: lateral approach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ibrutinib in Combination With Rituximab and Lenalidomide in Treating Patients With Previously Untreated, Stage II-IV Follicular Lymphoma or Marginal Zone Lymphoma
Status: COMPLETED
Conditions: Ann Arbor Stage II Follicular Lymphoma|Ann Arbor Stage II Marginal Zone Lymphoma|Ann Arbor Stage III Follicular Lymphoma|Ann Arbor Stage III Marginal Zone Lymphoma|Ann Arbor Stage IV Follicular Lymphoma|Ann Arbor Stage IV Marginal Zone Lymphoma|CD20 Positive|Grade 1 Follicular Lymphoma|Grade 2 Follicular Lymphoma|Grade 3a Follicular Lymphoma
Interventions: DRUG: Ibrutinib|OTHER: Laboratory Biomarker Analysis|DRUG: Lenalidomide|BIOLOGICAL: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Electroacupuncture With or Without Combined Warm Needling for Tinnitus
Status: RECRUITING
Conditions: Tinnitus|Tinnitus, Subjective
Interventions: PROCEDURE: Electroacupuncture (EA)|PROCEDURE: Electroacupuncture Combined With Warm Needling (EAWN)|OTHER: Waitlist Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Safety Trial of MVA-BN®-PRO in Men With Androgen-Insensitive Prostate Cancer
Status: COMPLETED
Conditions: Androgen-insensitive Prostate Cancer
Interventions: BIOLOGICAL: MVA-BN-PRO|BIOLOGICAL: MVA-BN-PRO|BIOLOGICAL: MVA-BN-PRO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reducing Alcohol Dependence Among HIV-Positive Individuals
Status: COMPLETED
Conditions: Alcohol Dependence
Interventions: BEHAVIORAL: Clinician's Guide|BEHAVIORAL: Enhanced Motivational Interviewing|BEHAVIORAL: Enhanced Clinician's Guide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of TKI Maintenance Therapy Following Allo-HSCT in Newly Diagnosed Ph+ Adult ALL
Status: UNKNOWN
Conditions: Precursor Cell Lymphoblastic Leukemia-Lymphoma|Philadelphia-Positive Acute Lymphoblastic Leukemia|ALL, Adult
Interventions: DRUG: Dasatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Repetitive Lipid Intake and Food Intake
Status: UNKNOWN
Conditions: Satiation|Overweight and Obesity|Satiety Response
Interventions: DIETARY_SUPPLEMENT: Yogurt A: Active|DIETARY_SUPPLEMENT: Yogurt B: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Effect of Pioglitazone on the Course of New Onset Type 1 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus
Interventions: DRUG: pioglitazone|DRUG: Placebo control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Modifying Progesterone and Estradiol Levels to Prevent Postpartum Cigarette Smoking Relapse and Reduce Secondhand Smoke Exposure in Infants and Children
Status: RECRUITING
Conditions: Smoking|Smoking Cessation|Smoking Reduction
Interventions: DRUG: Progesterone 200 MG Oral Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Group Based Parent Training for Children With Autism and Disruptive Behaviors
Status: UNKNOWN
Conditions: Autism Spectrum Disorder
Interventions: BEHAVIORAL: "Parent training for disruptive behaviors" manual (Bearss, Johnson, Handen, Butter, Lecavalier, Smith & Scahill, 2018)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sofosbuvir and Ribavirin in Patients With Chronic HCV With Cirrhosis and Portal Hypertension With or Without Liver Decompensation
Status: COMPLETED
Conditions: Hepatitis C|Cirrhosis|Portal Hypertension|With or Without Liver Decompensation
Interventions: DRUG: SOF|DRUG: RBV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of LAU-7b for the Treatment of COVID-19 Disease in Adults
Status: COMPLETED
Conditions: COVID-19 Disease
Interventions: DRUG: LAU-7b|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Surufatinib in Combination With Tislelizumab in Subjects With Advanced Solid Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Solid Tumor|Colorectal Cancer|Neuroendocrine Tumors|Small Cell Lung Cancer|Gastric Cancer|Soft Tissue Sarcoma|Anaplastic Thyroid Cancer
Interventions: DRUG: Surufatinib and Tislelizumab _ Part 1|DRUG: Surufatinib and Tislelizumab _ Part 2
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized Controlled Study of the Efficacy and Safety of Maintenance Treatment With Oral Ganciclovir for Newly Diagnosed Cytomegalovirus Retinitis in People With AIDS
Status: COMPLETED
Conditions: Cytomegalovirus Retinitis|HIV Infections
Interventions: DRUG: Ganciclovir
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Longitudinal Experimental Study on ULNTT and Cervico-Thoracic Spine Motion Patterns Relationship
Status: COMPLETED
Conditions: Cervicobrachial Neuralgia
Interventions: OTHER: Spinal Manipulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Bromocriptine in Dilated Cardiomyopathy Among Women of Reproductive Age
Status: RECRUITING
Conditions: Dilated Cardiomyopathy
Interventions: DRUG: GDMT plus Bromocriptine mesylate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial to Evaluate the Safety and Efficacy of the Passeo-18 Lux Drug-coated Balloon of Biotronik in the Treatment of the Femoropopliteal Artery Compared to the Medtronic IN.PACT Admiral Drug-coated Balloon.
Status: ACTIVE_NOT_RECRUITING
Conditions: Peripheral Arterial Disease
Interventions: DEVICE: Passeo-18 Lux treatment group|DEVICE: IN.PACT Admiral treatment group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Laparascopy Versus Laparatomy in the Management of Ruptured Ectopic Pregnancy
Status: COMPLETED
Conditions: Ruptured Ectopic Pregnancy
Interventions: PROCEDURE: Laparotomy arm|PROCEDURE: Laparoscopy arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ancef Dosage in Knee Arthroplasty : Tourniquet Clinical Trial
Status: RECRUITING
Conditions: Infections Joint Prosthetic
Interventions: OTHER: Use of Tourniquet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Pharmacokinetic and Safety Profile of Androxal in Male Subjects With Impaired Renal Function
Status: COMPLETED
Conditions: Secondary Hypogonadism
Interventions: DRUG: Androxal 25 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety, Pharmacokinetics and Pharmacodynamics of BIRB 796 BS Tablets Administered to Healthy Human Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BIBR 796 BS|DRUG: Placebo|OTHER: high fat breakfast
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Multi-component Intervention to Improve Medication Adherence in People With Depressive Disorders
Status: COMPLETED
Conditions: Depressive Disorder
Interventions: BEHAVIORAL: Intervention to Patients|BEHAVIORAL: Intervention to Psychiatrists|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety, Pharmacokinetics and Pharmacodynamics of BMS-936559 in Severe Sepsis
Status: TERMINATED
Conditions: Severe Sepsis|Septic Shock
Interventions: BIOLOGICAL: BMS-936559|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Antiviral Therapy After Radical Resection for Hepatitis B Virus-Related Hepatocellular Carcinoma
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma|Hepatitis B Virus|Recurrence
Interventions: DRUG: antiviral treatment (lamivudine or entecavir)|PROCEDURE: radical resection of HBV-related HCC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Intravenous Almitrine in Reducing the Need for Mechanical Ventilation in Patients With Hypoxemic Acute Respiratory Failure Due to Covid-19-related Pneumonia
Status: COMPLETED
Conditions: Covid 19|Hypoxemic Respiratory Failure
Interventions: DRUG: Almitrine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Loncastuximab Tesirine in Combination With DA-EPOCH-R in Patients With Previously Untreated Aggressive B-cell Lymphoid Malignancies
Status: RECRUITING
Conditions: B-cell Lymphoma|Burkitt Lymphoma
Interventions: DRUG: Etoposide|DRUG: Doxorubicin|DRUG: Cyclophosphamide|DRUG: Rituximab|DRUG: Vincristine|DRUG: Prednisone|DRUG: Loncastuximab Tesirine 0.075 mg/kg by IV|DRUG: Loncastuximab tesirine 0.12 mg/kg by IV|DRUG: Loncastuximab tesirine 0.15 mg/kg by IV
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Global Study to Evaluate Transarterial Chemoembolization (TACE) in Combination With Durvalumab and Bevacizumab Therapy in Patients With Locoregional Hepatocellular Carcinoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Durvalumab|DRUG: Bevacizumab|OTHER: Placebo|PROCEDURE: Transarterial Chemoembolization (TACE)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Optimal Precision TherapIes to CustoMISE Care in Childhood and Adolescent Cancer
Status: RECRUITING
Conditions: Childhood Cancer|Childhood Solid Tumor|Childhood Brain Tumor|Recurrent Cancer|Refractory Cancer
Interventions: DRUG: Paxalisib, Irinotecan, Temozolomide|DRUG: Pimasertib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Remifentanil Versus Rocuronium for Optimizing Video Laryngoscopy-assisted Tracheal Intubation
Status: NOT_YET_RECRUITING
Conditions: Tracheal Intubation|Video Laryngoscopy|Remifentanil|Rocuronium
Interventions: DRUG: Remifentanil|DRUG: Rocuronium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Post Market Clinical Follow-up Study for Arthroplasty Shoulder System of FX Solutions at the Long Term
Status: UNKNOWN
Conditions: Shoulder Disease|Shoulder Fractures|Shoulder Arthroplasty for Revision of Previous Treatment
Interventions: DEVICE: Shoulder Arthroplasty Surgery with HUMELOCK I & II® Anatomic Shoulder System|DEVICE: Shoulder Arthroplasty Surgery with HUMELOCK II® Reversible System|DEVICE: Shoulder Arthroplasty Surgery with HUMELOCK Reversed® Shoulder System|DEVICE: Shoulder Arthroplasty Surgery with EASYTECH® Anatomic Shoulder System|DEVICE: Shoulder Arthroplasty Surgery with EASYTECH® Reversed System (Primary intention)|DEVICE: Shoulder Arthroplasty Surgery with EASYTECH® Reversible System (for revision only)|DEVICE: Shoulder Arthroplasty Surgery with HUMERIS® Anatomic Shoulder System|DEVICE: Shoulder Arthroplasty Surgery with HUMERIS® Reversible Shoulder System
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Preoperative Silicone Ointment and Wound Healing
Status: ENROLLING_BY_INVITATION
Conditions: Wound Heal|Scar|Scar, Hypertrophic|Keloid|Keloid Scar Following Surgery|Surgical Incision
Interventions: DEVICE: Preoperative silicone ointment|OTHER: Preoperative placebo ointment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Genotype-guided Supportive Care in Symptom Treatment of Cancer Patients
Status: TERMINATED
Conditions: Chemotherapy|Supportive Care|Genotyping
Interventions: DIAGNOSTIC_TEST: Genotype-guided Supportive Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Tolerability and Pharmacokinetics/-Dynamics of Single Rising Doses BIBT 986 BS in Healthy Male Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BIBT 986 BS - single rising dose|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Longitudinal Early-onset Alzheimer's Disease Study Protocol
Status: RECRUITING
Conditions: Early Onset Alzheimer Disease|Alzheimer Disease|Mild Cognitive Impairment
Interventions: DRUG: Flortaucipir|DRUG: Florbetaben|DRUG: Fluorodeoxyglucose
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Evaluate the Effect of Renal Impairment on JNJ-64417184 and Its Two Minor Metabolites JNJ-68294291 and JNJ-65201526 in Adult Participants
Status: TERMINATED
Conditions: Renal Impairment
Interventions: DRUG: JNJ-64417184
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Investigation of Efficacy and Safety of Electrical Signal Therapy Provided by Dr Biolyse® Device in COVID-19 Disease
Status: COMPLETED
Conditions: COVID-19 Pneumonia|Virus Diseases|COVID-19
Interventions: DEVICE: Signal Therapy provided by Dr.Biolyse device|OTHER: Liquid Support Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Emergence of RAS Mutations in Metastatic Colorectal Cancer Patients Receiving Cetuximab Treatment
Status: UNKNOWN
Conditions: Colorectal Cancer|Drug Resistance|Mass Spectrometry|RAS-RAF Pathway Deregulation
Interventions: DRUG: Cetuximab|DIAGNOSTIC_TEST: liquid biopsy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Role of the Very Low Calorie Ketogenic Diet (VLCKD) in Patients With Non-Alcoholic Steatohepatitis (NASH) With Fibrosis
Status: RECRUITING
Conditions: NASH|NAFLD|Obesity|Liver Fibrosis
Interventions: DIETARY_SUPPLEMENT: Very-low-calorie ketogenic diet (VLCKD) with meal replacements|DIETARY_SUPPLEMENT: Mediterranean low-calorie diet (LCD)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Gd-EOB-DTPA-enhanced MRI and Contrast-enhanced Ultrasound for Measuring Tumor Size of Solitary Hepatocellular Carcinoma ≤ 5cm:A Retrospective Study
Status: COMPLETED
Conditions: HCC - Hepatocellular Carcinoma
Interventions: RADIATION: ceus
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Sleep Disturbance and Emotion Regulation Brain Dysfunction as Mechanisms of Neuropsychiatric Symptoms in Alzheimer's Dementia
Status: RECRUITING
Conditions: Alzheimer Disease|Mild Cognitive Impairment|Neuropsychiatric Symptoms|Sleep Disturbance
Interventions: BEHAVIORAL: Cognitive Behavioral Therapy for Insomnia (CBT-I)|BEHAVIORAL: Desensitization Therapy for insomnia (DT-I)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Preparation Regimens to Improve Capsule Endoscopy Visualization and Diagnostic Yield
Status: UNKNOWN
Conditions: Obscure Gastrointestinal Bleeding
Interventions: COMBINATION_PRODUCT: Moviprep
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Efficacy and Safety of Risedronate Therapy Administered 35 mg Once A Week in Men With Osteoporosis
Status: COMPLETED
Conditions: Other Osteoporosis
Interventions: DRUG: Placebo tablet|DRUG: Risedronate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: DEcentralize Testing, Education, and Linkage to Care by Using Electronic Best Practice Advisory for Hepatitis B (DETECT-B)
Status: NOT_YET_RECRUITING
Conditions: Viral Hepatitis B
Interventions: OTHER: An enhanced model of hepatitis B testing and linkage to care
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Targeted Radiation Therapy for Ovarian Cancer: Intraperitoneal Treatment With 211-astatine-MX35 F(ab')2
Status: COMPLETED
Conditions: Ovarian Cancer
Interventions: COMBINATION_PRODUCT: 211-astatine MX35 F(ab')2
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Associations Between Obesity, Dental Caries, Erosive Tooth Wear and Periodontal Disease in Adolescents: A Case Control-study
Status: COMPLETED
Conditions: Obesity|Obesity, Childhood|Tooth Wear|Tooth Erosion|Dental Caries|Dental Plaque|Gingivitis
Interventions: OTHER: Dental examination
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Partial Versus Miniature Pulpotomy in Teeth With Irreversible Pulpitis
Status: UNKNOWN
Conditions: Pulpitis - Irreversible
Interventions: PROCEDURE: Partial pulpotomy|PROCEDURE: Miniature pulpotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Exenatide in Type 2 Diabetic Patients With Congestive Heart Failure
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus|Congestive Heart Failure
Interventions: DRUG: exenatide|DRUG: Insulin glargine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transperineal Repair of Primary Obstetric Rectovaginal Fistulas
Status: COMPLETED
Conditions: Recto Vaginal Fistula
Interventions: PROCEDURE: rectovaginal fistula repair with Martius flap
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Serologic Response to SHINGRIX Vaccine in Patients With CLL and WM Treated With BTK Inhibitors
Status: COMPLETED
Conditions: Chronic Lymphocytic Leukemia (CLL)|Waldenstrom Macroglobulinemia (WM)
Interventions: DRUG: Shingrix vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: DElivery of Self Training and Education for Stressful Situations-Primary Care Version
Status: COMPLETED
Conditions: Posttraumatic Stress Disorder (PTSD)
Interventions: BEHAVIORAL: DESTRESS-PC|OTHER: Optimized Usual Primary Care PTSD treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study of Monitoring Insulin Levels and Treating Hyperinsulinemia and Hyperglycemia With Pioglitazone in Patients Treated With Alpelisib for Metastatic Breast Cancer.
Status: RECRUITING
Conditions: Metastatic Breast Cancer|Hyperinsulinism|Hyperglycemia Drug Induced
Interventions: DRUG: Pioglitazone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Patient Preference, Sleep Quality, and Anxiety/Depression: A Comparison of Raltegravir and Efavirenz
Status: UNKNOWN
Conditions: Sleep Disorders|HIV Infections
Interventions: DRUG: Raltegravir for the first 2 weeks|DRUG: Efavirenz for the last 2 weeks|DRUG: Efavirenz for the first 2 weeks|DRUG: Raltegravir for the last 2 weeks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Hand Puppets and Kaleidoscope on Pain and Fear in Preschool Children
Status: COMPLETED
Conditions: Nursing Caries|Pain|Fear of Pain
Interventions: OTHER: Hand puppet method|OTHER: Kaleidoscope method
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Binaural Beat Music Combined With Rhythmic Photic Stimulation on Depression
Status: COMPLETED
Conditions: Depression
Interventions: OTHER: Binaural Beat Music (BBM) Combined with Rhythmic Photic Stimulation (RPS)|OTHER: Sham group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluating the Safety and Efficacy of Autologous Adipose Tissue-derived Mesenchymal Stem Cell Transplantation on Proinflammatory Cytokines and Anti-inflammatory Cytokines on Ageing-related Low-grade Inflammation Patients.
Status: RECRUITING
Conditions: Aging Problems|Aging|Chronic Inflammation
Interventions: BIOLOGICAL: autologous adipose-derived mesenchymal stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Temperature Management on Postoperative Delirium
Status: NOT_YET_RECRUITING
Conditions: Emergence Delirium
Interventions: DEVICE: 3M™ Bair Hugger™ Warming Unit
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Self-assured Parents - a Parenting Support Program for Immigrant Parents With Teenage Children Living in Deprived Areas
Status: ACTIVE_NOT_RECRUITING
Conditions: Parenting|Parent-Child Relations|Adolescent Behavior
Interventions: BEHAVIORAL: Self-Assured Parenting program
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Success Rate of Three Capping Materials
Status: COMPLETED
Conditions: Caries
Interventions: PROCEDURE: Nanohydroxyapatite Pulpotomy|PROCEDURE: MTA pulpotomy|PROCEDURE: Formocresol Pulpotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Erenumab on Functional Impact of Migraine
Status: COMPLETED
Conditions: Migraine
Interventions: DRUG: Erenumab-Aooe 140 MG/ML [Aimovig]
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Bioavailability Study of ODM-201 in Subjects With Metastatic Chemotherapy-naive Castration-resistant Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: ODM-201 Tablet A|DRUG: ODM-201 Tablet B|DRUG: ODM-201 capsule formulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Clinical Of Plain Balloon Dilatation Combined Stent Versus Endovascular Debulking Combined Drug-coated Balloon to Treat Arteriosclerosis Occlusive Disease of Lower Extremity
Status: RECRUITING
Conditions: Atherosclerosis|Ischemia
Interventions: DEVICE: balloon and Stent|DEVICE: endovascular debulking and DCB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pelvic Organs Prolapse Treatment Using Neodymium Laser
Status: RECRUITING
Conditions: Pelvic Organ Prolapse|Female Urogenital Diseases
Interventions: DEVICE: Laser Treatment|DIAGNOSTIC_TEST: Blood analysis|DIAGNOSTIC_TEST: Сlinical urine test|DIAGNOSTIC_TEST: Electrocardiography|DIAGNOSTIC_TEST: Vaginal smear|DIAGNOSTIC_TEST: Colposcopy|DIAGNOSTIC_TEST: Pelvic ultrasound|DIAGNOSTIC_TEST: Doppler ultrasonography|DIAGNOSTIC_TEST: Vaginal Health Index|DIAGNOSTIC_TEST: Biopsy of the vaginal wall|DIAGNOSTIC_TEST: The Pelvic Organ Prolapse/Urinary Incontinence Sexual Questionnaire|DIAGNOSTIC_TEST: Pelvic Floor Distress Inventory Questionnaire|DIAGNOSTIC_TEST: International Consultation on Incontinence Questionnaire - Short Form|DIAGNOSTIC_TEST: Pelvic Floor Impact Questionnaire|PROCEDURE: Anterior and/or posterior colporrhaphy|PROCEDURE: Pelvic surgical procedure|OTHER: Physical examination|OTHER: Сonsultation|GENETIC: Buccal smear
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study on β-elemene as Maintain Treatment for Newly Diagnosed Malignant Gliomas
Status: UNKNOWN
Conditions: Anaplastic Oligoastrocytoma|Anaplastic Astrocytoma|Glioblastoma
Interventions: DRUG: β-elemene
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MK0431 (Sitagliptin) and Metformin Co-Administration Factorial Study in Patients With Type 2 Diabetes Mellitus (0431-036)
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Comparator: MK0431 50 mg b.i.d. (b.i.d. = twice daily)|DRUG: Comparator: MK0431 100 mg q.d. (q.d. = once daily)|DRUG: Comparator: Placebo (Phase A)/Metformin (Phase B)|DRUG: Comparator: Metformin 500 mg b.i.d.|DRUG: Comparator: Open-Label MK0431/Metformin 50/1000 mg b.i.d.|DRUG: Comparator: Metformin 1000 mg b.i.d.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Exercise Training in Patients With Atrial Fibrillation (OPPORTUNITY Study)
Status: ACTIVE_NOT_RECRUITING
Conditions: Atrial Fibrillation
Interventions: BEHAVIORAL: moderate-intensity continuous exercise training|BEHAVIORAL: high-intensity interval training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Pharmacokinetic Profile of Two Formulations of PB1023 Following Single Subcutaneous Injection in Subjects With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Single Dose PB1023|DRUG: Single Dose PB1023|DRUG: Single Dose PB1023
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Study of Sensation and Satisfaction in Cancer and Transgender Mastectomy Patients
Status: RECRUITING
Conditions: Sensation Disorders|Sensation, Phantom|Pain, Postoperative|Pain, Chronic|Numbness|Sensory Disorder|Sensory Defect|Phantom Pain|Phantom Sensation
Interventions: DIAGNOSTIC_TEST: Sensory testing
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Lymphoedema and Nocturia/ Nocturnal Polyuria After Pelvic Lymph Node Dissection for Urogenital Cancer
Status: RECRUITING
Conditions: Lower Limb Lymphedema|Urogenital Cancer
Interventions: OTHER: Manual lymph drainage|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Durvalumab and Tremelimumab Compared to Doxorubicin in Patients With Advanced or Metastatic Soft Tissue Sarcoma
Status: COMPLETED
Conditions: Metastatic Adult Soft Tissue Sarcoma|Recurrent Adult Soft Tissue Sarcoma
Interventions: BIOLOGICAL: Durvalumab and Tremelimumab|DRUG: Doxorubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of a Systemic Mindfulness-based Intervention Program in a Cystic Fibrosis Clinic
Status: UNKNOWN
Conditions: Cystic Fibrosis
Interventions: BEHAVIORAL: active interventional program based on Mindfulness training
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: HEAL STUDY (Hepatic Encephalopathy and Albumin Study)
Status: COMPLETED
Conditions: Cirrhosis|Hepatic Encephalopathy|Minimal Hepatic Encephalopathy|Covert Hepatic Encephalopathy
Interventions: BIOLOGICAL: 25% IV albumin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Isostretching Effects in Patients With Mechanical and Postural Chronic Low Back Pain
Status: COMPLETED
Conditions: Chronic Low Back Pain
Interventions: OTHER: Isostretching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Radiation Therapy and Chemotherapy in Treating Patients With Cancer of the Pancreas or Stomach
Status: COMPLETED
Conditions: Gastric Cancer|Pancreatic Cancer
Interventions: DRUG: cisplatin|DRUG: gemcitabine hydrochloride|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Chlorhexidine Bathing on MRSA and VRE Colonization Among Haematology-Oncology ICU Patients
Status: COMPLETED
Conditions: MRSA Colonization|VRE Colonization
Interventions: OTHER: Bed bathing with 2% CHG solution|OTHER: Bed bathing with soap and water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy of Omega-3 Free Fatty Acids in Adolescents With Obesity and Hypertriglyceridemia.
Status: COMPLETED
Conditions: Hypertriglyceridemia|Pediatric Obesity
Interventions: DIETARY_SUPPLEMENT: Omega-3 fatty acid 3 grams per day|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Assessing Repeatability and Intra-individual Variability in [O15]H2O-PET Myocardial Perfusion Imaging
Status: RECRUITING
Conditions: Myocardial Blood Flow
Interventions: DIAGNOSTIC_TEST: Myocardial perfusion imaging (MPI) using [O15]H2O-PET-CT
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Oral Steroid in Mycoplasma Pneumoniae Pneumonia
Status: UNKNOWN
Conditions: Mycoplasma Pneumoniae Pneumonia
Interventions: DRUG: Prednisolone|DRUG: Levofloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stress and Gingival Inflammation in Non-pregnant and Pregnant Women
Status: COMPLETED
Conditions: Periodontal Diseases|Pregnancy Gingivitis
Interventions: PROCEDURE: periodontal treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cognitive Therapy Software for Improving Cognitive Function for Patients With Mild Cognitive Impairment
Status: RECRUITING
Conditions: Mild Cognitive Impairment|MCI
Interventions: DEVICE: SB-100|OTHER: Educational book
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PSMA Expression and PSMA PET Imaging in Soft Tissue Sarcomas and Urothelial Cell Carcinomas
Status: RECRUITING
Conditions: Sarcoma,Soft Tissue|Urothelial Carcinoma
Interventions: DIAGNOSTIC_TEST: [18F]-JK-PSMA-7 PET/CT scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC