pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Comprehensive Smoking Cessation Intervention Duration Radiation for Upper Aerodigestive Cancers
Status: COMPLETED
Conditions: Tobacco Use Disorder|Head and Neck Neoplasms|Thoracic Neoplasms|Radiation
Interventions: OTHER: Comprehensive smoking cessation intervention|BEHAVIORAL: Enhanced usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Obexelimab in Patients With Systemic Lupus Erythematosus
Status: NOT_YET_RECRUITING
Conditions: Systemic Lupus Erythematosus
Interventions: DRUG: Obexelimab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Oral Atogepant When Added to OnabotulinumtoxinA (BOTOX) to Assess Adverse Events and Change in Disease Activity in Adult Participants With Chronic Migraine
Status: RECRUITING
Conditions: Chronic Migraine
Interventions: DRUG: Atogepant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Comparing Tenofovir Disoproxil Fumarate (TDF), Emtricitabine (FTC)/TDF, and Entecavir (ETV) in the Treatment of Chronic HBV in Subjects With Decompensated Liver Disease.
Status: COMPLETED
Conditions: Chronic Hepatitis B
Interventions: DRUG: Tenofovir disoproxil fumarate (tenofovir DF; TDF)|DRUG: Emtricitabine/tenofovir disoproxil fumarate (FTC/TDF)|DRUG: Entecavir (ETV)|DRUG: TDF placebo|DRUG: FTC/TDF placebo|DRUG: ETV placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Intracranial Wide-neck Aneurysms Using Stent-assisted Coil Embolization
Status: COMPLETED
Conditions: Intracranial Aneurysms
Interventions: DEVICE: Neuroform EZ Stent System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Miller Class I and II Gingival Recession Using Non- Pedicled Buccal Fat Pad Graft as Compared to Subepithelial Connective Tissue Graft
Status: NOT_YET_RECRUITING
Conditions: Gingival Recession
Interventions: PROCEDURE: Non- Pedicled Buccal Fat Pad with Coronally Advanced flap|PROCEDURE: sub-epithelial connective tissue graft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Simulation-based Intervention for Caregivers of Children With Seizures
Status: COMPLETED
Conditions: Dependency on Medications Prescribed for Patient|Types of Seizures and Epileptic Syndromes
Interventions: BEHAVIORAL: Simulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effects of Rosuvastatin on the, in Vivo, Kinetic of apoB and apoA1, Using Stable Isotopes, in Type 2 Diabetic Patients
Status: COMPLETED
Conditions: Diabetes
Interventions: DRUG: Rosuvastatin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Stereotactic Radiosurgery After Surgery in Treating Patients With Brain Metastases
Status: TERMINATED
Conditions: Metastatic Cancer|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: BEHAVIORAL: MMSE|BEHAVIORAL: QOL via FACT-Br|PROCEDURE: MRI|RADIATION: Post-operative SRS
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Study of Huaier Granule in Postoperative Adjuvant Therapy of Resectable Pancreatic Cancer
Status: RECRUITING
Conditions: Pancreatic Cancer Resectable
Interventions: DRUG: Huaier granule|DRUG: chemotherapy drugs
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Local Anesthesia With Lidocaine During Insertion and Removal of Nasal Packing
Status: UNKNOWN
Conditions: Epistaxis|Analgesia
Interventions: DRUG: Xylocaine Mucosal Product|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Peer to Peer Mentoring: Facilitating Individuals With Early Inflammatory Arthritis to Manage Their Arthritis - Peer Mentor Training
Status: COMPLETED
Conditions: Early Inflammatory Arthritis|Chronic Disease
Interventions: BEHAVIORAL: peer mentor training
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: |Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Using the Duracore Splinting Device on Patient Outcomes Related to Chest Trauma
Status: TERMINATED
Conditions: Rib Fractures|Rib Fracture Multiple
Interventions: DEVICE: Chest Splint
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Segmentectomy Versus Lobectomy for Non-small Cell Lung Cancer ≤ 2 cm in the Middle Third of the Lung Field
Status: RECRUITING
Conditions: Lung Neoplasms|Surgery
Interventions: PROCEDURE: Segmentectomy|PROCEDURE: Lobectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Safety, Pharmacokinetics, Pharmacodynamics, and Anti-Cancer Activity of Trametinib in Combination With Palbociclib in Subjects With Solid Tumors
Status: COMPLETED
Conditions: Cancer
Interventions: DRUG: Trametinib|DRUG: Palbociclib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Interactive Stepping Exercise on Memory
Status: UNKNOWN
Conditions: Amnestic Mild Cognitive Impairment|Interactive Stepping Exercise|Memory|Cognitive Function|Executive Function
Interventions: OTHER: Interactive stepping exercise|OTHER: Home exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Adductor Canal Block With Periarticular Injection and IPACK (ACB/PAI/IPACK) Versus Periarticular Injection (PAI)
Status: COMPLETED
Conditions: Knee Arthropathy
Interventions: DRUG: Bupivacaine with epinephrine|DRUG: Methylprednisolone|DRUG: Cefazolin|DEVICE: 8 MHz. Chiba needle|DRUG: Bupivacaine with Dexamethasone|DRUG: Bupivacaine 25cc|DRUG: Bupivacaine 20cc|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pembrolizumab (MK-3475) and Bacillus Calmette-Guérin (BCG) as First-Line Treatment for High-Risk T1 Non-Muscle-Invasive Bladder Cancer (NMIBC) and High-Grade Non-Muscle-Invasive Upper Tract Urothelial Carcinoma (NMI-UTUC)]
Status: RECRUITING
Conditions: Bladder Cancer
Interventions: DRUG: Pembrolizumab (MK-3475)|DRUG: Bacillus Calmette-Guérin (BCG)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study to Determine Feasibility of Home-based Cardiac Rehabilitation in Patients With Chronic Heart Failure (Pilot-CRHF)
Status: NOT_YET_RECRUITING
Conditions: Heart Failure
Interventions: BEHAVIORAL: Home-based cardiac rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Impact of Two Different Types of Sedation on ICEB
Status: COMPLETED
Conditions: Propofol|Dexmedetomidine|Electrophysiological Balance Index|QT Interval, Variation in|Tp-e Interval|QT Dispersion|Knee Osteoarthritis
Interventions: OTHER: Sedation with propofol|OTHER: sedation with dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vital Signs-Integrated Patient-Assisted Intravenous Opioid Analgesia for Post Surgical Pain
Status: ACTIVE_NOT_RECRUITING
Conditions: Pain|Respiratory Depression
Interventions: DEVICE: VPIA pump|DRUG: Morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vision-based Speed of Processing Cognitive Training and Mild Cognitive Impairment
Status: COMPLETED
Conditions: Mild Cognitive Impairment
Interventions: BEHAVIORAL: Vision-based speed of processing training|BEHAVIORAL: Mental leisure activities
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Optimal Time for Tenofovir Treatment of Anti-Hepatitis B Virus (HBV) During the Pregnancy
Status: UNKNOWN
Conditions: Hepatitis B, Chronic
Interventions: DRUG: Tenofovir Disoproxil Fumarate|DRUG: Tenofovir Disoproxil Fumarate|DRUG: Tenofovir Disoproxil Fumarate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Study to Evaluate the Safety, Efficacy, Pharmacokinetics and Pharmacodynamics of PF-06252616 in Duchenne Muscular Dystrophy
Status: TERMINATED
Conditions: Duchenne Muscular Dystrophy
Interventions: BIOLOGICAL: PF-06252616|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Attention Bias Modification Treatment for Anxious Youth
Status: TERMINATED
Conditions: Generalized Anxiety Disorder|Separation Anxiety Disorder|Social Phobia|Specific Phobia|Obsessive-Compulsive Disorder
Interventions: OTHER: Attention Bias Modification Computer Task|OTHER: Placebo Computer Task
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fluvoxamine for Adults With Mild to Moderate COVID-19
Status: SUSPENDED
Conditions: Severe Acute Respiratory Syndrome Coronavirus 2|Coronavirus Infection|Mild to Moderate COVID-19
Interventions: DRUG: Fluvoxamine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Exenatide in Patients With Type 2 Diabetes Using Metformin or Sulfonylureas and Metformin
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: exenatide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Possible Ameliorating Effect of N- Acetylcysteine (NAC) on Type-II Diabetes Induced Nephropathy
Status: UNKNOWN
Conditions: Diabetic Kidney Disease|Diabetes Mellitus, Type 2|Diabetic Nephropathies
Interventions: DRUG: N Acetylcysteine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Acupuncture for Discogenic Sciatica
Status: UNKNOWN
Conditions: Sciatica
Interventions: PROCEDURE: Acupuncture|PROCEDURE: Sham acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Go Girls! Fitness Support Group Intervention Effectiveness Study
Status: RECRUITING
Conditions: Polycystic Ovary Syndrome|Abnormal Weight Gain|Excess Weight|Insulin Resistance|Premature Adrenarche|Type 2 Diabetes Mellitus
Interventions: BEHAVIORAL: Go Girls! Fitness Support Group
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Efficacy of CCX140-B in Subjects With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Placebo|DRUG: pioglitazone|DRUG: CCX140-B|DRUG: CCX140-B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: FOLFOX Via HAI Plus Intravenous Irinotecan With or Without Bevacizumab Versus Systemic FOLFOXIRI With or Without Bevacizumab in Initially Unresectable RAS-mutated CRLM Patients
Status: RECRUITING
Conditions: Colorectal Cancer Metastatic
Interventions: DRUG: Dexamethasone|DRUG: Anisodamine|DRUG: Oxaliplatin|DRUG: Leucovorin|DRUG: Fluorouracil|DRUG: Irinotecan|DRUG: Bevacizumab|DRUG: Oxaliplatin|DRUG: Leucovorin|DRUG: Fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radiation Therapy in Treating Patients Receiving Hormone Therapy for Prostate Cancer (GETUG-AFU 18)
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Cancer
Interventions: RADIATION: 3-dimensional conformal radiation therapy|RADIATION: intensity-modulated radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Erlotinib and Momelotinib for the Treatment of Epidermal Growth Factor Receptor (EGFR) Mutated EGFR Tyrosine Kinase Inhibitor (TKI) Naive Metastatic Non-Small Cell Lung Cancer (NSCLC)
Status: TERMINATED
Conditions: EGFR Mutated EGFR TKI Naive Metastatic NSCLC
Interventions: DRUG: Momelotinib (MMB)|DRUG: Erlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exercise Prehabilitation Among Older Patients With Hematological Malignancies Preparing For CAR-T Cell Immunotherapy
Status: RECRUITING
Conditions: Lymphoma|Leukemia|Myeloma
Interventions: BEHAVIORAL: Resistance Training|BEHAVIORAL: Aerobic Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Analysis of Intestinal Microflora Combined With DNA Methylation in Stool to Detect Colorectal Cancer
Status: UNKNOWN
Conditions: Gastrointestinal Microbiome|DNA Methylation|Colorectal Neoplasms
Interventions: OTHER: Fecal microbiota detection and exfoliated cell gene detection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: huCART19-IL18 in NHL/CLL Patients
Status: RECRUITING
Conditions: Chronic Lymphocytic Leukemia|Non-hodgkin Lymphoma|Acute Lymphoblastic Leukemia
Interventions: BIOLOGICAL: huCART19-IL18
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Temozolomide as a Prophylaxis Against Brain Recurrence in Participants With Metastatic Breast Cancer (P05225 AM2)
Status: TERMINATED
Conditions: Breast Neoplasm|Brain Neoplasm|Second Neoplasm
Interventions: DRUG: temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Pilot Study on Comparisons Between the Effectiveness of Mobile Video-guided and Paper-based Home Exercise Programs of Patients With Stroke Randomized Controlled Trial
Status: COMPLETED
Conditions: Stroke
Interventions: BEHAVIORAL: Stroke physiotherapy home exercise video
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Singe Dose, First in Human Study of PF- 06946860 in Healthy Adult Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: BIOLOGICAL: PF-06946860|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Analgesic Effect of Quadratus Lumborum Block in Laparoscopic Hemicolectomy
Status: UNKNOWN
Conditions: Post Operative Pain
Interventions: PROCEDURE: Quadratus lumborum block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Strengthening the Healthy Adult Mode: a Case Experimental Study Exploring the Effects of a New Schema Therapy Protocol in an Adult Outpatient Population.
Status: COMPLETED
Conditions: Trauma, Psychological|Personality Disorders|Chronic Psychiatric Disorder
Interventions: BEHAVIORAL: Schema Therapy and the Healthy Adult
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PPX and Concurrent Radiation for Newly Diagnosed Glioblastoma Without MGMT Methylation
Status: COMPLETED
Conditions: Glioblastoma Multiforme
Interventions: DRUG: PPX (CT2103)|DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intermittent Preventive Treatment With Antimalarials in Kenyan Infants
Status: COMPLETED
Conditions: Malaria|Anemia
Interventions: DRUG: sulfadoxine-pyrimethamine with artesunate|DRUG: amodiaquine with artesunate|DRUG: chlorproguanil-dapsone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Cisplatin, Gemcitabine, Interferon Alfa, and Hyperthermia in Treating Patients With Advanced Cancer
Status: UNKNOWN
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: BIOLOGICAL: recombinant interferon alfa|DRUG: cisplatin|DRUG: gemcitabine hydrochloride|PROCEDURE: hyperthermia treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Effect of 13-Week Treatment With Vildagliptin as Add-On Therapy to Improve Glucose Variability in Type II Diabetes
Status: TERMINATED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Vildagliptin|DRUG: Insulin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Safety of Dezocine Pretreatment for Pain Relief in Acne Scar Treatment of Fractional CO2 Laser
Status: RECRUITING
Conditions: Acne Atrophica
Interventions: DEVICE: Fractional CO2 laser|DRUG: Dezocine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effectiveness of Sequential Eustachian Tube Maneuvers in Hyperbaric Oxygen Conditions
Status: ACTIVE_NOT_RECRUITING
Conditions: Barotrauma;Ear|Tympanum; Perforation
Interventions: BEHAVIORAL: Maneuver group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pharmacokinetic Study of Antibiotics in Patients Assisted by Extracorporeal Membrane Oxygenation (PHARMECMO)
Status: COMPLETED
Conditions: Extracorporeal Membrane Oxygenation|Sepsis|Intensive Care Unit|Antibiotics
Interventions: OTHER: Antibiotic plasma dosage
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study Evaluating ANV600 Single Agent or in Combination With Pembrolizumab in Participants With Advanced Solid Tumors (EXPAND-1)
Status: RECRUITING
Conditions: Advanced Solid Tumor
Interventions: DRUG: ANV600|DRUG: ANV600 + pembrolizumab (KEYTRUDA®)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Immunogenicity of a Single Dose of Adsorbed Tetanus Vaccine in a Population Aged 18 Years and Over
Status: ACTIVE_NOT_RECRUITING
Conditions: Tetanus
Interventions: BIOLOGICAL: TTVA|BIOLOGICAL: TT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Impact of a Ketogenic Diet on Metabolic and Psychiatric Health in Patients With Bipolar Illness
Status: NOT_YET_RECRUITING
Conditions: Bipolar Disorder I|Bipolar II Disorder|Bipolar I Disorder|Bipolar Disorder|Bipolar Depression|Bipolar and Related Disorders|Bipolar Disorder, Type 1|Bipolar Disorder, Type 2|Bipolar Disorder, Mixed|Obesity|Metabolic Syndrome|Ketogenic Dieting|Weight Gain|Brain Metabolic Disorder|Psychotropic Agents Causing Adverse Effects in Therapeutic Use
Interventions: OTHER: LCHF Ketogenic Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Trial of Neoadjuvant Weekly Carboplatin Plus Paclitaxel in Triple Negative Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Triple Negative Breast Cancer
Interventions: DRUG: Carboplatin|DRUG: Paclitaxel|DRUG: Doxorubicin|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Real-World Evidence Study to Evaluate Oral Health Related Quality of Life Using an Anti-Sensitivity Toothpaste
Status: COMPLETED
Conditions: Dentin Sensitivity
Interventions: OTHER: Potassium Nitrate + Sodium Fluoride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Impact of Empty Versus Full Bladder in Patients With Prostate Cancer, RELIEF Trial
Status: RECRUITING
Conditions: Prostate Carcinoma
Interventions: OTHER: Best Practice|PROCEDURE: Computed Tomography|OTHER: Electronic Health Record Review|PROCEDURE: Imaging Technique|OTHER: Questionnaire Administration|RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fu's Subcutaneous Needling on the Myofascial Trigger Points: Lateral Epicondylitis
Status: UNKNOWN
Conditions: Lateral Epicondylitis
Interventions: PROCEDURE: Fu's subcutaneous needling|PROCEDURE: Transcutaneous electrical nerve stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Effectiveness of Intravenous Immune Globulin (10%) for the Treatment of Multifocal Motor Neuropathy
Status: COMPLETED
Conditions: Multifocal Motor Neuropathy
Interventions: BIOLOGICAL: Immune Globulin Intravenous (human), 10%|BIOLOGICAL: 0.25% human albumin solution (Placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Progesterone Therapeutic Regimen Plus Statins in Young Women With Early Endometrial Carcinoma and Atypical Endometrial Hyperplasia
Status: RECRUITING
Conditions: Atypical Endometrial Hyperplasia and Endometrial Carcinoma Stage I
Interventions: DRUG: statins (oral atorvastatin calcium tablet 20mg/ day; Or rosuvastatin 5mg/ day; Or pivastatin 2mg/ day);
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics, Efficacy, Safety, and Immunogenicity of SB5 Versus Humira in Subjects With Moderate to Severe Chronic Plaque Psoriasis
Status: COMPLETED
Conditions: Plaque Psoriasis
Interventions: DRUG: Humira (Adalimumab)|DRUG: SB5 (Adalimumab Biosimilar)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ZF2001 Booster Immunization Clinical Trials of 6 Months After the Completion of Basic Immunization
Status: COMPLETED
Conditions: Prevention of COVID-19
Interventions: BIOLOGICAL: Recombinant novel coronavirus vaccine (CHO cells)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of HGS1036 in Combination With Chemotherapy in Subjects With Advanced Solid Malignancies
Status: SUSPENDED
Conditions: Cancer
Interventions: DRUG: HGS1036 + Paclitaxel + Carboplatin|DRUG: HGS1036 + Cisplatin + Etoposide|DRUG: HGS1036 + Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intratumorally-Administered Topotecan Using CED in High Grade Glioma Undergoing Stereotactic Biopsy
Status: WITHDRAWN
Conditions: Glioma
Interventions: DRUG: Topotecan (<=8cc)|DRUG: Topotecan (>8cc)|DEVICE: Cleveland Multiport Catheter|DIAGNOSTIC_TEST: Magnetic Resonance Imaging (MRI)|DRUG: Lower Does Topotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Deferasirox in Iron Overload From Beta-thalassemia Unable to be Treated With Deferoxamine or Chronic Anemias
Status: COMPLETED
Conditions: Beta-thalassemia|Myelodysplastic Syndromes|Fanconi Syndrome|Anemia, Diamond-Blackfan|Anemia, Aplastic
Interventions: DRUG: Deferasirox
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Septic cArdiac Deficiency and MenIngococcal seveRe Sepsis
Status: COMPLETED
Conditions: Meningococcal Infections|Septic Shock|Severe Sepsis
Interventions: BIOLOGICAL: BNP
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Perfusion Assessment With Indocyanine Green-SPY Angiography After Tissue Expander Filling
Status: COMPLETED
Conditions: Tissue Expander Disorder
Interventions: BEHAVIORAL: 60mmHg capsule pressure expansion|BEHAVIORAL: 70mmHg capsule pressure expansion|BEHAVIORAL: 80mmHg capsule pressure expansion|BEHAVIORAL: 90mmHg capsule pressure expansion|BEHAVIORAL: 100mmHg capsule pressure expansion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SUROVA - Surgery in Ovarian Cancer, Comparing Primary and Interval Cytoreductive Surgery
Status: RECRUITING
Conditions: Epithelial Ovarian Cancer|Fallopian Tube Neoplasms|Peritoneal Neoplasms
Interventions: PROCEDURE: Cytoreductive surgery|DRUG: Neoadjuvant chemotherapy|DRUG: Adjuvant chemotherapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pain Management in Children Undergoing Supracondylar Humerus Fracture Repair
Status: WITHDRAWN
Conditions: Humeral Fractures|Fractures, Closed
Interventions: PROCEDURE: Supraclavicular nerve block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study on the Correlation Between Tarceva (Erlotinib) - Induced Rash and Efficacy in EGFR Mutated Participants With Advanced Non-Small Cell Lung Cancer Receiving First-Line Therapy
Status: COMPLETED
Conditions: Non-Squamous Non-Small Cell Lung Cancer
Interventions: DRUG: erlotinib [Tarceva]
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Motor Imagery in Pain Modulation and Median Nerve Mechanosensitive in Healthy Patients
Status: COMPLETED
Conditions: Median Nerve Injury
Interventions: OTHER: Action observation|OTHER: Mirror therapy|OTHER: Neurodynamic exercises|OTHER: Strength
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Enteral Nutrition Biscuits for Inducing Remission in Moderate-to-severe Crohn's Disease
Status: NOT_YET_RECRUITING
Conditions: Crohn's Disease
Interventions: DIETARY_SUPPLEMENT: enteral nutrition biscuits
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy Followed by Surgery in Treating Patients With Localized Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: docetaxel|DRUG: mitoxantrone hydrochloride|PROCEDURE: conventional surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Berberine, Chlorogenic Acid and Tocotrienols in Menopause-associated Dyslipidemia
Status: COMPLETED
Conditions: Dyslipidemia
Interventions: DIETARY_SUPPLEMENT: Nutraceutical|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Improve Physician-Youth Communication and Medical Decision Making
Status: COMPLETED
Conditions: Heart Failure NYHA Class II|Heart Failure NYHA Class III|Heart Failure NYHA Class IV
Interventions: BEHAVIORAL: We Chatt communication tool|BEHAVIORAL: Usual/standard care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Head Down Tilt 15° to Increase Collateral Flow in Acute Ischemic Stroke
Status: NOT_YET_RECRUITING
Conditions: Acute Ischemic Stroke
Interventions: PROCEDURE: HEAD DOWN TILT -10° to -15°
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intraarterial Infusion of Autologous Bone Marrow in Diabetic Patients With Chronic Ischemia of Lower Limbs (CLI) no Revascularization
Status: COMPLETED
Conditions: Critical Limb Ischemia (CLI)|Diabetic Foot
Interventions: OTHER: Intraarterial infusion of autologous bone marrow cells
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Pharmacokinetics of NTP42:KVA4
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: NTP42:KVA4|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized, Placebo-Controlled Clinical Trial of Intravitreal Triamcinolone for Refractory Diabetic Macular Edema
Status: COMPLETED
Conditions: Diabetic Macular Edema
Interventions: DRUG: Triamcinolone acetonide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: OligoCare TwiCs (Trials Within Cohorts) Trial Comparing Acute Toxicity in Single-fraction vs Multiple-fraction SBRT for Metastasis-directed Treatment (SPRINT)
Status: NOT_YET_RECRUITING
Conditions: Breast Cancer|Prostate Cancer|NSCLC|Colorectal Cancer|Oligometastatic Disease
Interventions: RADIATION: single-fraction SBRT|RADIATION: multiple-fraction SBRT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating CERAMENT™|G in Open Diaphyseal Tibial Fractures
Status: COMPLETED
Conditions: Tibial Fracture
Interventions: DEVICE: CERAMENT|G|PROCEDURE: SOC treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ALXN1210 (Ravulizumab) Versus Eculizumab in Complement Inhibitor Treatment-Naïve Adult Participants With Paroxysmal Nocturnal Hemoglobinuria (PNH)
Status: COMPLETED
Conditions: Paroxysmal Nocturnal Hemoglobinuria (PNH)
Interventions: BIOLOGICAL: Ravulizumab|BIOLOGICAL: Eculizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Morning Light Treatment to Improve Glucose Metabolism
Status: COMPLETED
Conditions: PreDiabetes|Circadian Dysregulation
Interventions: OTHER: Bright Light|OTHER: Dim Light
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PERFECT Project - Part 2 - Study 3
Status: COMPLETED
Conditions: Diabetes Prevention|Obesity Prevention
Interventions: OTHER: Control|OTHER: Pea flour|OTHER: Pea fibre|OTHER: Pea flour and pea fibre|OTHER: Pea flour and pea protein|OTHER: Pea flour + pea fibre + pea protein
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Dose-Finding Study to Evaluate the Safety, Efficacy and Pharmacokinetics of Adalimumab in Subjects With Refractory Asthma
Status: WITHDRAWN
Conditions: Asthma
Interventions: DRUG: Humira (adalimumab)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Effect of Bispectral Index (BIS) Titrated Propofol Sedation on Lower Esophageal Sphincter Pressures and Esophageal Function in Intensive Care Patients
Status: TERMINATED
Conditions: Respiration, Artificial
Interventions: OTHER: BIS 70 maintained|OTHER: BIS level 50|OTHER: BIS 35
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study to Evaluate the Safety and Efficacy of GSK1278863 in Recombinant Human Erythropoietin (rhEPO) Hyporesponsive Hemodialysis-dependent Chronic Kidney Disease Subjects With Anemia
Status: TERMINATED
Conditions: Anemia
Interventions: DRUG: GSK1278863|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Bavituximab Plus Docetaxel in Patients With Locally Advanced or Metastatic Non-Squamous Non Small-Cell Lung Cancer
Status: COMPLETED
Conditions: Non-small-cell Lung Cancer
Interventions: DRUG: Docetaxel plus bavituximab or placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rehabilitation and Cortical Remodeling After Surgical Intervention for Spinal Cord Injury
Status: ACTIVE_NOT_RECRUITING
Conditions: Spinal Cord Injuries|Tetraplegia|Cervical Spinal Cord Injury
Interventions: DEVICE: Upper limb robotic training|PROCEDURE: Nerve transfer surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study of EC17 (Folate-hapten Conjugate) in Patients With Progressive Metastatic Renal Cell Carcinoma
Status: TERMINATED
Conditions: Renal Cell Carcinoma
Interventions: BIOLOGICAL: EC90 (KLH-FITC)|BIOLOGICAL: GPI-0100|DRUG: EC17 (Folate-FITC)|DRUG: Interleukin-2|DRUG: Interferon-alpha
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The MIND Study: Modifying the INcidence of Delirium
Status: COMPLETED
Conditions: Delirium|Cognition Disorders
Interventions: DRUG: Ziprasidone|DRUG: Haloperidol|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Genetic Testing to Understand and Address Renal Disease Disparities
Status: COMPLETED
Conditions: Hypertension|Chronic Kidney Disease|Genomics
Interventions: OTHER: Immediate Genetic Testing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of the Use of Resources and Costs
Status: UNKNOWN
Conditions: Surgical Incision
Interventions: PROCEDURE: Device O-Arm in DBS|PROCEDURE: Device O-Arm in RAQUIS|PROCEDURE: Not device O-Arm in DBS|PROCEDURE: Not device O-Arm in RAQUIS
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Feasibility Study of the TGI Adipose-derived Stromal Cell (ASC)-Coated ePTFE Vascular Graft
Status: UNKNOWN
Conditions: Lower Limb Ischemia
Interventions: DEVICE: ASC coated ePTFE vascular graft|DEVICE: Propaten graft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hepatic Arterial Infusion Chemotherapy Combined With Sintilimab and Regorafenib as Adjuvant Therapy for Colorectal Liver Metastasis Patients With a High Risk of Recurrent: a Single-arm, Phase II Study
Status: RECRUITING
Conditions: Colorectal Liver Metastasis
Interventions: COMBINATION_PRODUCT: HAIC-FOLFOX combined with Sintilimab and Regorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Use and Safety of the Fentanyl Transdermal Therapeutic System (TTS) in the Management of Pain in Patients With Cancer
Status: COMPLETED
Conditions: Pain|Cancer
Interventions: DRUG: Fentanyl Transdermal Therapeutic System (TTS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility and Tolerance of Nivolumab Neoadjuvant Immunotherapy in High Risk HPV Driven Oropharynx Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Oropharynx Cancer
Interventions: DRUG: Nivolumab|RADIATION: Chemoradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TMS-EEG for Cortical Excitability
Status: WITHDRAWN
Conditions: Acquired Brain Injury|Stroke|Traumatic Brain Injury|Healthy
Interventions: DIAGNOSTIC_TEST: Electroencephalogram|PROCEDURE: Transcranial Magnetic Stimulation|PROCEDURE: Transcranial Direct Current Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Mindful Parenting and Parent Training Program Study
Status: COMPLETED
Conditions: Disruptive Behavior|Attention Deficit Hyperactivity Disorder|Oppositional Defiant Disorder|Conduct Disorder|Disruptive Behavior Disorder
Interventions: BEHAVIORAL: Mindful Parenting Program|BEHAVIORAL: MATCH BPT Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Trial of Chemohormonal Therapy Followed by Prostatectomy in High Risk Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: Docetaxel|DRUG: Degarelix|DRUG: Bicalutamide|RADIATION: Ferumoxytol-enhanced MRI imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of TQ-B3525 Tablets in Subjects With PIK3CA and/or PIK3R1/2 Gene-altered Recurrent/Metastatic Advanced Gynecologic Tumors
Status: UNKNOWN
Conditions: Advanced Endometrial Cancer, Cervical Cancer and Ovarian Cancer
Interventions: DRUG: TQ-B3525 tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Etoricoxib 30 mg Versus Celecoxib 200 mg in Korean Participants With Osteoarthritis
Status: COMPLETED
Conditions: Osteoarthritis of the Knee
Interventions: DRUG: Etoricoxib 30 mg|DRUG: Celecoxib 200 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Adherence to Once Monthly Ibandronate (Bonviva) in Women With Post-Menopausal Osteoporosis, Supported by a Patient Relationship Program (PRP)
Status: COMPLETED
Conditions: Postmenopausal Osteoporosis
Interventions: DRUG: Ibandronate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Blood Glucose Self Monitoring and HbA1c Effects on Glucose Control
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: PROCEDURE: weekly blood glucose profile|PROCEDURE: three-monthly haemoglobin A1c|PROCEDURE: no blood-glucose self-control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Disc Resorption in Lumbar and Cervical Disc Herniation Patients Receiving Integrative Korean Medicine Treatment
Status: COMPLETED
Conditions: Lumbar Intervertebral Disc Displacement|Cervical Intervertebral Disc Displacement
Interventions: DRUG: Herbal medicine|PROCEDURE: Acupuncture|PROCEDURE: Pharmacopuncture|PROCEDURE: Bee venom pharmacopuncture|PROCEDURE: Chuna manipulation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The IMPACT of a Referral Model for Axial Spondyloarthritis in Young Patients With Chronic Low Back Pain
Status: UNKNOWN
Conditions: Chronic Low Back Pain|Axial Spondyloarthritis
Interventions: OTHER: Applying a referral model
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Cisplatin and Pemetrexed With Radiation Followed by Lobectomy
Status: TERMINATED
Conditions: Nonsquamous Nonsmall Cell Neoplasm of Lung|Nonsmall Cell Lung Cancer Stage III
Interventions: DRUG: Pemetrexed|DRUG: Carboplatin|RADIATION: Radiation Therapy|DRUG: Pemetrexed|DRUG: Cisplatin|RADIATION: Radiation Therapy|PROCEDURE: Lobectomy|PROCEDURE: Lobectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Effectiveness and Safety of Amphotericin B With Flucytosine-Fluconazole Therapy for Cryptococcal Meningitis
Status: COMPLETED
Conditions: Cryptococcal Meningitis
Interventions: DRUG: Amphotericin B 1 mg/kg 1 week & Flucytosine 100 mg/kg 1 week followed by Fluconazole 1200 mg/day 1 week
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Beta Cell Rescue in New Onset Type 1 Diabetes With Efalizumab
Status: WITHDRAWN
Conditions: Diabetes Mellitus, Type 1
Interventions: DRUG: efalizumab|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SWITCH - Sensing With Insulin Pump Therapy to Control HbA1c
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: DEVICE: insulin pump with continuous glucose sensing (Paradigm Real-Time Insulin Pump System)|DEVICE: insulin pump and blinded continuous glucose sensing (Paradigm Real-Time insulin pump)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Drug Delivery Via Pressurized Metered-dose Inhaler and Valved Holding Chamber in Asthmatic Children: Determination of Delivered Dose Following Coordinated and Uncoordinated Use
Status: COMPLETED
Conditions: Asthma
Interventions: DEVICE: Pressurized Metered-Dose Inhaler
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Stellate Ganglion Block for Hot Flushes in Men Treated With ADT
Status: WITHDRAWN
Conditions: Prostate Cancer
Interventions: PROCEDURE: Stellate ganglion block|PROCEDURE: Sham procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Acute Effect of CPAP on Weight in Patients With Obstructive Sleep Apnea
Status: COMPLETED
Conditions: Obstructive Sleep Apnea
Interventions: DEVICE: Continuous Positive Airway Pressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Phase 1a/b Study of IK-175 as a Single Agent and in Combination With Nivolumab in Patients With Locally Advanced or Metastatic Solid Tumors and Urothelial Carcinoma
Status: COMPLETED
Conditions: Urothelial Carcinoma|Urothelial Carcinoma Bladder|Bladder Cancer|Bladder Disease|Solid Tumor|Solid Carcinoma|Solid Tumor, Adult|Metastatic Cancer|Advanced Solid Tumor|Advanced Cancer|Metastatic Bladder Cancer|Metastatic Urothelial Carcinoma|Locally Advanced Solid Tumor|Neoplasms|Neoplasm Metastasis|Neoplasm Malignant|Neoplasm, Bladder|Urothelial Neoplasm|Neoplasm, Urinary Bladder|Bladder Neoplasm|Bladder Urothelial Carcinoma
Interventions: DRUG: IK-175|DRUG: IK-175 and nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Understand What the Body Does to the Study Medicine Called PF-07220060 When Taken by Healthy Adults
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DRUG: Oral [14C]PF-07220060|DRUG: Oral PF-07220060|DRUG: IV [14C] PF-07220060
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Reversibility of Brain Glucose Transport in Type 2 Diabetes Mellitus (T2DM)
Status: RECRUITING
Conditions: Diabetes Mellitus, Type 2
Interventions: OTHER: Magnetic Resonance Spectroscopy Imaging (MRSI)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety and Immunogenicity of a Cell Culture-derived Influenza Vaccine in Healthy Adults and Elderly
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Cell culture-derived trivalent subunit influenza vaccine (cTIV)|BIOLOGICAL: Egg-derived trivalent subunit influenza vaccine (TIV)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION