pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Comprehensive Patient Questionnaires in Predicting Complications in Older Patients With Gynecologic Cancer Undergoing Surgery
Status: COMPLETED
Conditions: Endometrial Serous Adenocarcinoma|Fallopian Tube Carcinoma|Malignant Female Reproductive System Neoplasm|Ovarian Carcinoma|Primary Peritoneal Carcinoma|Stage IIIA Uterine Corpus Cancer AJCC v7|Stage IIIB Uterine Corpus Cancer AJCC v7|Stage IIIC Uterine Corpus Cancer AJCC v7|Stage IVA Uterine Corpus Cancer AJCC v7|Stage IVB Uterine Corpus Cancer AJCC v7
Interventions: OTHER: Comprehensive Geriatric Assessment|OTHER: Questionnaire Administration
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Pilot Study to Assess the Suitability of the HealthBeacon Injection Care Management System (ICMS) as a Remote Therapeutic Monitoring (RTM) Device
Status: ENROLLING_BY_INVITATION
Conditions: Respiratory Disease
Interventions: DEVICE: HealthBeacon Injection Care Management System (ICMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study Evaluating the Safety, Pharmacokinetics, Pharmacodynamics and Efficacy of Crovalimab for the Management of Acute Uncomplicated Vaso-Occlusive Episodes (VOE) in Participants With Sickle Cell Disease (SCD).
Status: RECRUITING
Conditions: Sickle Cell Disease
Interventions: DRUG: Crovalimab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Magnetic Resonance Imaging of Interscalene Plexus Block
Status: COMPLETED
Conditions: Disorder of Shoulder
Interventions: PROCEDURE: Interscalene Nerve Block|DRUG: Ropivacaine 0.75%, 20ml|DRUG: Gadopentetate-Dimeglumine 0.0125 mmol|DRUG: Gadopentetate-Dimeglumine 0.05 mmol|DRUG: Ropivacaine 0.75%, 5ml|PROCEDURE: Shoulder Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Opioid Versus Non-opioid Anesthesia for Ambulatory Surgery in Children
Status: COMPLETED
Conditions: Effect of Anesthesia in Postoperative Pain|Effect of Anesthesia in Extubation Time|Effect of Anesthesia in Discharge Time From Postanesthesia Care Unit|Effect of Anesthesia in Postoperative Adverse Events|Effect of Anesthesia in Discharge Time From the Hospital
Interventions: DRUG: Ketamine, dexmedetomidine|DRUG: fentanyl, remifentanil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Clinical Study to Evaluate the Efficacy and Safety of VR506 Using a New Inhaler for the Treatment of Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: VR506
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Factors and Prognostic Significance of Impaired Exercise Tolerance in Women Over 40 With Arterial Hypertension
Status: COMPLETED
Conditions: Arterial Hypertension|Heart Failure
Interventions: DIAGNOSTIC_TEST: Diagnostic tests
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Safety and Effectiveness Prospective Blinded Clinical Study to Validate xBar System as Monitoring Tool for Anastomotic Leaks Detection
Status: NOT_YET_RECRUITING
Conditions: Colorectal Surgery|Anastomotic Leak
Interventions: DIAGNOSTIC_TEST: xBar system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: First Line Weekly Chemo/Immunotherapy for Metastatic Head/Neck Squamous Cell Carcinoma Patients
Status: RECRUITING
Conditions: Head Neck Cancer|Metastatic Squamous Cell Carcinoma|Oral Cavity Squamous Cell Carcinoma|Oropharynx Squamous Cell Carcinoma|Hypopharynx Squamous Cell Carcinoma|Larynx Squamous Cell Carcinoma
Interventions: DRUG: Pembrolizumab|DRUG: Carboplatin|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Oral SNC-102 in Subjects With Combat-Related Posttraumatic Stress Disorder
Status: WITHDRAWN
Conditions: Post-Traumatic Stress Disorders|Posttraumatic Stress Disorders|Stress Disorders, Post-Traumatic|Post-Traumatic Stress Disorders, Combat-related
Interventions: DRUG: SNC-102 sustained release tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of APG-2575 in Patients With Mild-to-moderate Systemic Lupus Erythematosus.
Status: NOT_YET_RECRUITING
Conditions: SLE
Interventions: DRUG: APG-2575|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Black Raspberry Confection in Preventing Oral Cancer in Healthy Volunteers
Status: ACTIVE_NOT_RECRUITING
Conditions: Healthy Volunteers
Interventions: OTHER: Fast release BRB confection|OTHER: Intermed release BRB confection|OTHER: Prolong release BRB confection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Confocal Endomicroscopy for Non-Erosive Reflux Disease (CE NERD)
Status: WITHDRAWN
Conditions: Gastroesophageal Reflux Disease|Non Erosive Reflux Disease|Dyspepsia
Interventions: DEVICE: Confocal endomicroscopy|DRUG: Proton pump inhibitor|DRUG: Sucralfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: High Definition Endoscopy and Virtual Chromoendoscopy Versus Standard Resolution Endoscopy in Detection of Colon Polyps
Status: COMPLETED
Conditions: Colonic Adenoma
Interventions: DIAGNOSTIC_TEST: High-definition|DIAGNOSTIC_TEST: Virtual chromoendoscopy|DIAGNOSTIC_TEST: Standard
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Allo-HSCT With Alternative Donor in Treatment of Hematologic Malignancy
Status: COMPLETED
Conditions: Acute Leukemia|Chronic Myeloid Leukemia|Myelodysplastic Syndrome
Interventions: PROCEDURE: HSCT from MSD|PROCEDURE: HSCT from MUD|PROCEDURE: HSCT from HRD|DRUG: Cyclosporin A|DRUG: Methotrexate|DRUG: Antithymocyte globulin|DRUG: Mycophenolate mofetil
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neuroinflammation in Amyotrophic Lateral Sclerosis - Mechanisms and Therapeutic Perspectives: a Translational Pilot Study Among ALS Patients
Status: UNKNOWN
Conditions: Amyotrophic Lateral Sclerosis (ALS)
Interventions: OTHER: ALS Functional rating Scale-revised (ALS FRS-R)|OTHER: slow vital capacity|OTHER: Blood sample|OTHER: Cerebrospinal Fluid (CSF) sample
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Effect of Intake of Hydrolyzed Krill Protein Isolate on Plasma Amino Acid Profile
Status: COMPLETED
Conditions: Human Nutrition
Interventions: DIETARY_SUPPLEMENT: Krill protein hydrolysate|DIETARY_SUPPLEMENT: Soy protein isolate|DIETARY_SUPPLEMENT: Whey protein isolate|DIETARY_SUPPLEMENT: Water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Amrubicin Study for Elderly Patients With Extensive-disease Small-cell Lung Cancer (ED-SCLC)
Status: TERMINATED
Conditions: Small-cell Lung Cancer
Interventions: DRUG: Amrubicin Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Flow Cytometric Analysis of Peripheral Blood Neutrophil Myeloperoxidase Expression for Ruling Out Myelodysplastic Syndromes: Protocol for a Diagnostic Accuracy Study
Status: RECRUITING
Conditions: Myelodysplastic Syndromes
Interventions: DIAGNOSTIC_TEST: Flow cytometric analysis of neutrophil myeloperoxidase expression
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety of a Single Dose of Canakinumab (ACZ885) in Hospitalized Patients With Acute Gout
Status: COMPLETED
Conditions: Arthritis, Gouty
Interventions: BIOLOGICAL: canakinumab|DRUG: dexamethasone|OTHER: placebo matching canakinumab|OTHER: placebo matching dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Testing of Drugs Erlotinib and Docetaxel in Lung Cancer Patients Classified Regarding Their Outlook Using VeriStrat®.
Status: COMPLETED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: Erlotinib|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety/Efficacy of Induction Agents With Tacrolimus, MMF, and Rapid Steroid Withdrawal in Renal Transplant Recipients
Status: COMPLETED
Conditions: Kidney Transplantation
Interventions: DRUG: basiliximab|DRUG: rabbit anti-thymocyte globulin|DRUG: tacrolimus|DRUG: alemtuzumab|DRUG: mycophenolate mofetil|DRUG: steroids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pre-Market Study of the American Medical Systems (AMS) Transobturator Male Sling System for the Treatment of Male Stress Urinary Incontinence
Status: COMPLETED
Conditions: Urinary Incontinence, Stress
Interventions: DEVICE: The AMS Male Transobturator Sling System|DEVICE: AdVance Male Sling
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Efficacy of Tacrolimus and Clobetasol Propionate in Alopecia Areata
Status: COMPLETED
Conditions: Alopecia Areata
Interventions: DRUG: Group A applied topical Clobetasol Propionate|DRUG: Group B applied topical Tacrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I Trial of FLAC (5-Fluorouracil, Leucovorin, Adriamycin, Cytoxan) Plus GM-CSF (Granulocyte-Macrophage Colony Stimulating Factor) Plus Dose Escalation of IL-3 (Interleukin-3) in Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Neoplasms|Neoplasm Metastasis
Interventions: DRUG: IL-3
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Transplantation of Autologous Adipose Derived Stem Cells (ADSCs) in Spinal Cord Injury Treatment
Status: UNKNOWN
Conditions: Acute Spinal Cord Injury
Interventions: DEVICE: Laminectomy|DEVICE: Intradural space|DEVICE: Intrathecal|DEVICE: Intravenous
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity of a Reduced Primary Schedule for Pneumococcal Conjugate Vaccine in UK Infants
Status: COMPLETED
Conditions: Streptococcus Pneumoniae
Interventions: BIOLOGICAL: 9 valent pneumococcal con jugate vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Latent Tuberculosis in Second Generation Immigrants From High Risk Countries Compare to Low-risk Young Israeli Adults
Status: COMPLETED
Conditions: Latent Tuberculosis
Interventions: PROCEDURE: Answering the study Questionnaire and blood sampling for Interferon gamma release assay (IGRA)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Motivated to Move: A Study to Determine the Feasibility of Self-Monitoring Physical Activity in Youth
Status: UNKNOWN
Conditions: Chronic Disease|Child|Adolescent
Interventions: BEHAVIORAL: Usual care|BEHAVIORAL: Monitor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluate the Long Term Safety and Efficacy of DWP16001 add-on to Metformin in Patients With T2DM Inadequately Controlled on Metformin
Status: COMPLETED
Conditions: T2DM (Type 2 Diabetes Mellitus)
Interventions: DRUG: DWP16001
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Fosmidomycin and Clindamycin in the Treatment of Acute Uncomplicated Plasmodium Falciparum Malaria
Status: UNKNOWN
Conditions: Malaria
Interventions: DRUG: Fosmidomycin and clindamycin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TOCCATA - Touch+™ for Catheter Ablation
Status: COMPLETED
Conditions: Atrial Fibrillation|Tachycardia, Supraventricular
Interventions: DEVICE: Contact force assisted irrigated RF ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy for 1st Line Treatment of Advanced or Metastatic Pancreatic Cancer
Status: COMPLETED
Conditions: Metastatic Pancreatic Cancer
Interventions: DRUG: bevacizumab|DRUG: gemcitabine|DRUG: oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Impact of the Therapeutic Education on the Quality of Life of the Child Suffering of Food Allergy IgE-mediated
Status: COMPLETED
Conditions: IgE Mediated Food Allergy
Interventions: BEHAVIORAL: Therapeutic education group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of Esketamine on Patients Undergoing Tumor Surgery
Status: UNKNOWN
Conditions: Tumor Surgery
Interventions: DRUG: High-dose Esketamine hydrochloride+Hydromorphone|DRUG: Low-dose Esketamine hydrochloride+Hydromorphone|DRUG: Hydromorphone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acceleromyographic Assessment of Neuromuscular Blockade: TOF-Watch-SX Versus TOFscan
Status: UNKNOWN
Conditions: Neuromuscular Blockade
Interventions: DEVICE: TOFscan|DEVICE: TOF-Watch-SX
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Velcade (Bortezomib - PS341) in the Treatment of Patients Over 18 Years With Ph+ Leukemia
Status: COMPLETED
Conditions: Leukemia
Interventions: DRUG: Bortezomib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Mechanistic Trial of the Neurobiology of Extinction Learning and Intraparietal Sulcus Stimulation
Status: RECRUITING
Conditions: Posttraumatic Stress Disorder
Interventions: DEVICE: Continuous Theta Burst Stimulation to the Intraparietal Sulcus|DEVICE: Sham Continuous Theta Burst Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Clinical Study of Biosilicate Under Resin Composite Restorations in Caries Affected Teeth
Status: COMPLETED
Conditions: Dental Caries
Interventions: PROCEDURE: Adhesive system|PROCEDURE: Restoration protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Relationship Between the Strength of Ankle Movement Muscles and Postural Parameters in Elderly Fallers: Towards New Strategies for Screening and Management
Status: COMPLETED
Conditions: Persons Who Have Experienced a Sudden Uncontrolled Fall in the Absence of Outside Factors in the 6 Months Preceding the Consultation
Interventions: OTHER: BERG scale|OTHER: Functional tests|OTHER: Measurement of balance on a force platform|OTHER: Measurement of maximal moment of the plantar flexor and dorsiflexor muscles|OTHER: Measurement of the moment of the plantar flexors and dorsiflexors corresponding to RMS activity during balance measurements
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Enteral Albumin on Healing of Superficial Partial Thickness Fresh Flame Burns of Adults
Status: UNKNOWN
Conditions: Partial-thickness Burn
Interventions: DIETARY_SUPPLEMENT: Albumin supplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Pectin on Flora Intestinal Colonization and Maintenance After Fecal Transplantation
Status: UNKNOWN
Conditions: Inflammatory Bowel Disease
Interventions: OTHER: co-transplantation of FMT and pectin|OTHER: single fecal microbiota transplantation|DIETARY_SUPPLEMENT: pure give pectin 20g/d for five days
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Feasibility of Dynamic Muscle Stimulation + Radiofrequency for Improving Blink Quality in Subjects With Dry Eye Disease
Status: RECRUITING
Conditions: Eyelid Diseases|Eyelid Movement Disorders|Dry Eye|Dry Eye Syndromes|Skin Laxity
Interventions: DEVICE: TriLift device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Temporary Autonomic Blockade to Prevent Atrial Fibrillation After Cardiac Surgery
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DRUG: Botulinum Toxin Type A|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: NMDA-enhancing Agent for Treatment of Mild Cognitive Impairment and Mild Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer's Disease|Mild Cognitive Impairment
Interventions: DRUG: DAOI-B|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of PillCamCOLON (C2) Capsule and Standard Endoscopy for the Evaluation of Patients With Ulcerative Colitis
Status: UNKNOWN
Conditions: Ulcerative Colitis
Interventions: DEVICE: standard endoscopy|DEVICE: PillCamCOLON (C2)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Study To Assess Safety And Efficacy Of AsiDNA In Combination With Olaparib In Participants With Recurrent Solid Tumors
Status: RECRUITING
Conditions: Metastatic Castration-resistant Prostate Cancer|Recurrent Epithelial Ovarian Cancer|Breast Cancer
Interventions: DRUG: AsiDNA|DRUG: Olaparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Emotion Regulation Training on Anxiety, in College Students in Egypt
Status: COMPLETED
Conditions: Anxiety|Emotion Regulation
Interventions: BEHAVIORAL: Emotion Regulation training based on DBT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Light Load Blood Flow Restriction Training in Anterior Cruciate Ligament Reconstruction Patient Rehabilitation
Status: UNKNOWN
Conditions: Anterior Cruciate Ligament Injury
Interventions: DEVICE: Light load BFR resistance training|PROCEDURE: Heavy load resistance training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of PDR001 in Combination With LCL161, Everolimus or Panobinostat
Status: COMPLETED
Conditions: Colorectal Cancer, Non-small Cell Lung Carcinoma (Adenocarcinoma), Triple Negative Breast Cancer, Renal Cell Carcinoma
Interventions: BIOLOGICAL: PDR001|DRUG: LCL161|DRUG: Everolimus|DRUG: Panobinostat|DRUG: QBM076|DRUG: HDM201
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Influences Of Anterior Capsule Polishing On Anterior Capsular Changes and Intraocular Lenses Stability of Super High Myopic Eyes
Status: COMPLETED
Conditions: Myopia, High, With Cataract and Anterior Capsule Polished
Interventions: PROCEDURE: 360°anterior capsule polishing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Lu AF82422 in Healthy Non-Japanese and Japanese Subjects and in Patients With Parkinson's Disease
Status: COMPLETED
Conditions: Healthy|Parkinson Disease
Interventions: DRUG: Lu AF82422|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Impact of Menthol Flavoring on Switching in Adult Menthol Smokers
Status: RECRUITING
Conditions: Smoking Reduction
Interventions: OTHER: Menthol-flavored electronic cigarette|OTHER: Tobacco-flavored electronic cigarette
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Outcome Evaluation of Solutions for Wellness and Team Solutions Program in Patients With Severe Mental Illness
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder|Bipolar Disorder
Interventions: OTHER: Wellness Program
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Reappraisal Of Medical Assurance (ROMA): An Experimental Study in Patients With Functional Somatic Symptoms
Status: COMPLETED
Conditions: Somatic Symptom Disorder
Interventions: BEHAVIORAL: Immunization-enhancement|BEHAVIORAL: Immunization-inhibition|BEHAVIORAL: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Study of Immunogenicity of Quadrivalent Vaccine Against Human Papilloma Virus (HPV) Types 6, 11, 16, and 18 (HPV-6/11/16/18) in Chronic Kidney Disease (CKD) Patients
Status: UNKNOWN
Conditions: Chronic Kidney Disease, Stage IV (Severe)|Chronic Kidney Disease, Stage V
Interventions: BIOLOGICAL: HPV-6/11/16/18 vaccine
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: S9717 Tirapazamine Plus Cisplatin in Treating Patients With Metastatic, Recurrent, or Refractory Cervical Cancer
Status: COMPLETED
Conditions: Cervical Cancer
Interventions: DRUG: cisplatin|DRUG: tirapazamine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pityriasis Lichenoides Chronica, Role of Streptococcal Infection and Azithromycin
Status: UNKNOWN
Conditions: Pityriasis Lichenoides
Interventions: DRUG: Azithromycin|OTHER: nbUVB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: S0032, Combination Chemotherapy Plus Hormone Therapy in Treating Patients With Metastatic Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: bicalutamide|DRUG: estramustine|DRUG: etoposide|DRUG: flutamide|DRUG: goserelin|DRUG: leuprolide|DRUG: nilutamide|DRUG: paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Post-concussion Syndrome With TMS: Using FNIRS as a Biomarker of Response
Status: ACTIVE_NOT_RECRUITING
Conditions: Transcranial Magnetic Stimulation|Functional Near-Infrared Spectroscopy|Post-Concussion Syndrome|Concussion|Mild Traumatic Brain Injury|Post-traumatic Stress Disorder
Interventions: DEVICE: rTMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of BL-B01D1, SI-B003 and BL-B01D1+SI-B003 in Patients With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma (Non-nasopharyngeal Carcinoma) and Other Solid Tumors
Status: RECRUITING
Conditions: Head and Neck Squamous Cell Carcinoma
Interventions: DRUG: BL-B01D1|DRUG: SI-B003
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Pembrolizumab and Lenvatinib for Mucosal Melanoma
Status: WITHDRAWN
Conditions: Mucosal Melanoma
Interventions: DRUG: Pembrolizumab|DRUG: Lenvatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of IONIS-PKKRx for Preventive Treatment of Chronic Migraine
Status: COMPLETED
Conditions: Chronic Migraine
Interventions: DRUG: IONIS-PKKRx (ISIS 546254)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: To Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Multiple Doses AZD8848 in Healthy Subjects
Status: COMPLETED
Conditions: Safety,|Tolerability,|Healthy Subjects
Interventions: DRUG: AZD8848|DRUG: Placebo to match AZD8848
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of Von Willebrand Factor as a Marker For Early Diagnosis of Acute Respiratory Distress Syndrome (A.R.D.S) in Comparison to Interleukin 6 [IL-6]
Status: UNKNOWN
Conditions: ARDS, Human
Interventions: DIAGNOSTIC_TEST: VWF measurement
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Prucalopride in Postoperative Ileus
Status: COMPLETED
Conditions: Postoperative Ileus|Colorectal Surgery|Postoperative Complications
Interventions: DRUG: Prucalopride|DRUG: Placebo Oral Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Multicenter Phase II Trial of Post-operative Concurrent Chemoradiotherapy Using Weekly Cisplatin With Tislelizumab for Patients With High-risk Head and Neck Squamous Cell Carcinoma：The POTENTIAL Study
Status: UNKNOWN
Conditions: Head and Neck Cancer|Radiation|PD-1
Interventions: DRUG: Tislelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial to Evaluate Safety and Immunogenicity of an Ebola Zaire Vaccine in Healthy Adults
Status: COMPLETED
Conditions: Ebola Virus Disease
Interventions: BIOLOGICAL: Ebola Vaccine - low dose|BIOLOGICAL: Ebola Vaccine - mid dose|BIOLOGICAL: Ebola Vaccine - high dose|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Sacituzumab Govitecan for Advanced Esophageal Squamous Cell Carcinoma
Status: NOT_YET_RECRUITING
Conditions: Esophageal Squamous Cell Carcinoma
Interventions: DRUG: Sacituzumab govitecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Oral Iron Supplementation Before vs at Time of Vaccination on Immune Response in Iron Deficient Kenyan Women
Status: RECRUITING
Conditions: Iron Deficiency Anemia
Interventions: DIETARY_SUPPLEMENT: Iron supplementation|BIOLOGICAL: MenACWY vaccine|BIOLOGICAL: COVID-19 vaccine|OTHER: Placebo|BIOLOGICAL: Typhim Vi vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Study to Evaluate SAGE-217 in Participants With Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: DRUG: SAGE-217|DRUG: Levodopa|DRUG: Antiparkinsonian Agent(s)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Adherence to Topical Agents: Applying Communication Technology to Improve Sunscreen Use
Status: COMPLETED
Conditions: Skin Cancer
Interventions: DEVICE: Electronic + no text message|DEVICE: Electronic monitor + text messages
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: A Study to Evaluate SHR-1210 in Patients With Advanced or Metastatic NSCLC
Status: ACTIVE_NOT_RECRUITING
Conditions: Lung Neoplasms|Carcinoma, Non-Small-Cell Lung|Respiratory Tract Neoplasms Nec|Lung Disease|Respiratory Tract Disease|Neoplasm, Bronchial|Carcinoma, Bronchogenic
Interventions: BIOLOGICAL: SHR-1210
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Opsoclonus Myoclonus Syndrome/Dancing Eye Syndrome (OMS/DES) in Children With and Without Neuroblastoma (NBpos and NBneg)Opsoclonus Myoclonus Syndrome/Dancing Eye Syndrome (OMS/DES) in Children With and Without Neuroblastoma (NBpos and NBneg)
Status: ACTIVE_NOT_RECRUITING
Conditions: Opsoclonus Myoclonus Syndrome|Neuroblastoma
Interventions: DRUG: Dexamethasone acetate|DRUG: dexamethasone and cyclophosphamide|DRUG: dexamethasone and rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Eyelid Warming Technology for Meibomian Gland Dysfunction
Status: COMPLETED
Conditions: Meibomian Gland Dysfunction
Interventions: DEVICE: Blephasteam|DEVICE: EyeGiene|DEVICE: Hot compresses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Nucleoside Switch Pilot for Virologically Controlled HIV Subjects With Decreasing CD4 Cells Who Have Received TDF-based ARV Therapy
Status: COMPLETED
Conditions: HiV1- Positive
Interventions: DRUG: Abacavir/Lamivudine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Pembrolizumab Following Surgery in Patients With Microsatellite Instability High (MSI-H) Solid Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Solid Tumors|Identified by NGS, PCR or IHC
Interventions: DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Drug-Drug Interaction Study of CYP3A4 Inhibition and Pan-CYP Induction on APX001
Status: COMPLETED
Conditions: Fungal Infection
Interventions: DRUG: APX001|DRUG: Itraconazole|DRUG: Rifampin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Velusetrag for the Treatment of Chronic Intestinal Pseudo-Obstruction (CIPO).
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Intestinal Pseudo-obstruction
Interventions: DRUG: Velusetrag|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Determine the Haemostatic Efficacy of TT-173, Reducing the Bleeding Time in the Donor Site of Skin Grafting
Status: COMPLETED
Conditions: Burns|Traumatic Lesions
Interventions: DRUG: TT-173|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Proof of Concept Study of Serum Progesterone Levels for IVF/ICSI Following HCG Trigger for Oocyte Maturation
Status: COMPLETED
Conditions: Infertility|Infertility, Female|IVF|hCG
Interventions: DRUG: hCG|DIAGNOSTIC_TEST: Ultrasound|OTHER: Blood test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: "Peri-operative Antimicrobial Prophylaxis in Patients With Asymptomatic Bacteriuria of Enterobacteriacae ESBL+ Origin"
Status: UNKNOWN
Conditions: Antimicrobial Prophylaxis|Asymptomatic Bacteriuria
Interventions: PROCEDURE: Anti-microbial prophylaxis for an endourological procedure or ESWL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Wii Fit Game Based Abdomino-Pelvic Training In Urinary Incontinence
Status: COMPLETED
Conditions: Incontinence, Urinary
Interventions: OTHER: Wii Fit Training Experimental Group|OTHER: Conventional Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Brivaracetam as add-on Treatment of Unverricht-Lundborg Disease in Adolescents and Adults
Status: COMPLETED
Conditions: Unverricht-Lundborg Disease
Interventions: DRUG: Brivaracetam 25 mg|DRUG: Brivaracetam 50 mg|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Anesthesia for Vascular Access Devices
Status: COMPLETED
Conditions: Opioid Use, Unspecified|Remifentanil|Sedation Complication|Analgesia|Satisfaction, Patient|Vascular Access Complication
Interventions: DIAGNOSTIC_TEST: Comparison of pain intensity rating scale
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of ARQ-252 Cream in Subjects With Chronic Hand Eczema
Status: COMPLETED
Conditions: Chronic Hand Eczema
Interventions: DRUG: ARQ-252 cream 0.3%|DRUG: ARQ-252 cream 0.1%|DRUG: ARQ-252 Vehicle Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of Seroquel SR for Alcohol Dependence and Comorbid Anxiety
Status: COMPLETED
Conditions: Alcoholism|Anxiety Disorders|Generalized Anxiety Disorder|Post-Traumatic Stress Disorder|Panic Disorder|Obsessive-Compulsive Disorder
Interventions: DRUG: Seroquel XR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Imatinib Mesylate in Patients With Pulmonary Arterial Hypertension
Status: COMPLETED
Conditions: Pulmonary Arterial Hypertension
Interventions: DRUG: Imatinib mesylate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cognitive Behavioral Therapy for Treating Recently Abused Women With Post-Traumatic Stress Disorder
Status: COMPLETED
Conditions: Post-Traumatic Stress Disorder|Battered Women
Interventions: BEHAVIORAL: Helping to Overcome PTSD through Empowerment (HOPE)|BEHAVIORAL: Treatment as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Hemi-Ablative Prostate Brachytherapy
Status: COMPLETED
Conditions: Prostatic Neoplasms|Cancer of the Prostate
Interventions: RADIATION: Hemigland focal LDR brachytherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Effectiveness of VYC-12 Hyaluronic Acid Injectable Gel for Treatment of Superficial Cutaneous Depressions
Status: COMPLETED
Conditions: Skin Roughness
Interventions: DEVICE: VYC-12 HA injectable gel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized, Double-Blind, Placebo-Controlled Study to Examine the Effect of Betahistine on Plasma Lipids in Patients Treated With Simvastatin
Status: TERMINATED
Conditions: Hypercholesterolemia
Interventions: DRUG: Betahistine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Effects of Nicotine in Tobacco Smokers
Status: COMPLETED
Conditions: Smoking, Tobacco|Smoking (Tobacco) Addiction
Interventions: DRUG: Cigarette 1|DRUG: Cigarette 2|DRUG: Patch 1|DRUG: Patch 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation and Comparison of Women Pelvic Floor With and Without Sexual Dysfunction (Vaginismus)
Status: COMPLETED
Conditions: Vaginismus|Sexual Dysfunctions|Muscular Hypertonicity|Muscle Tone Poor
Interventions: OTHER: Evaluation and Comparison of women pelvic floor with and without sexual dysfunction|OTHER: The physiotherapeutic treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: A Trial to Assess the Efficacy and Safety of SPM 927 in Subjects With Painful Distal Diabetic Neuropathy
Status: COMPLETED
Conditions: Diabetic Neuropathy
Interventions: DRUG: SPM 927
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Antipsychotic Effects of Probiotics and Prebiotics on Patients With Schizophrenia
Status: UNKNOWN
Conditions: Schizophrenia
Interventions: DRUG: Probiotics（Live combined bifidobacteria, lactobacillus and maltodextrin tables)|DIETARY_SUPPLEMENT: Prebiotics (Combined inulin and maltodextrin tables)|DIETARY_SUPPLEMENT: maltodextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Study Aims to Show Bioequivalence of the Test Product and the Reference Reference Product in a Crossover Design Study Healthy Volunteers. Additionally, the Safety Profile of Test Product Compared to Reference Product Will be Assessed.
Status: COMPLETED
Conditions: To Determine Bioequivalence Under Fed Conditions
Interventions: DRUG: Metformin and Vildagliptin 850/50 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study of Guanábana Leaves for The Treatment of Patients With Gastric, Gastroesophageal Junction, Pancreatic and Colorectal Adenocarcinomas; Hepatocellular Carcinoma, and Low Grade Lymphomas
Status: UNKNOWN
Conditions: Gastric Adenocarcinoma|Adenocarcinoma of the Gastroesophageal Junction|Hepatocellular Carcinoma|Pancreatic Adenocarcinoma|Low Grade Lymphoma|Colorectal Adenocarcinoma
Interventions: DIETARY_SUPPLEMENT: Tea Made of Graviola Leaves
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Study of the Risk of Bacteremia in Directed Cholangioscopic Examination of the CBD
Status: COMPLETED
Conditions: Choledocholithiasis|Cholangiocarcinoma|Benign Stricture of Common Bile Duct
Interventions: OTHER: Blood culture ( aerobic and anaerobic)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Clinical Study to Evaluate the Safety,Tolerability and PK of ZYT1, Following Oral Administration in Healthy Volunteers
Status: TERMINATED
Conditions: Obesity|Lipid Disorders
Interventions: DRUG: ZYT1|DRUG: Placebo tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Aberrations in Carnitine Homeostasis in Congenital Heart Disease With Increased Pulmonary Blood Flow
Status: WITHDRAWN
Conditions: Heart Septal Defects, Ventricular|Atrioventricular Septal Defect
Interventions: DRUG: IV L-carnitine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Recovery of Oxytocin Responsiveness in Pregnant Human Myometrial Explants After Oxytocin-Induced Desensitization: an In-vitro Analysis of Oxytocin Receptor Expression and Signaling
Status: TERMINATED
Conditions: Postpartum Hemorrhage
Interventions: DRUG: Oxytocin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial in Healthy Volunteers and Patients With Mild Asthma to Investigate a New Medicine (AZD4604) for the Treatment of Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: AZD4604 for inhalation via DPI|DRUG: Placebo for AZD4604 for inhalation via DPI|DRUG: AZD4604 for IV administration|DRUG: AZD4604 for oral administration|DRUG: AZD4604 for inhalation via DPI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: World Health Organization (WHO) COVID-19 Solidarity Trial for COVID-19 Treatments
Status: UNKNOWN
Conditions: Covid19
Interventions: DRUG: Remdesivir|DRUG: Acalabrutinib|DRUG: Interferon beta-1a|OTHER: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Sacha Inchi Supplementation on Postprandial Inflammation
Status: COMPLETED
Conditions: Cardiovascular Diseases
Interventions: OTHER: High fat meal with Sacha Inchi|OTHER: high saturated fat meal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of Peginterferon Alfa-2a in Participants With Chronic Hepatitis B Virus (HBV) in an Expanded Access Program
Status: COMPLETED
Conditions: Hepatitis B, Chronic
Interventions: DRUG: Peginterferon alfa-2a
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Switching Between Intravitreal Bevacizumab (Avastin®)& Intravitreal Dexamethasone (Ozurdex™) for Persistent Diabetic Macular Oedema
Status: COMPLETED
Conditions: Diabetes|Diabetic Macular Oedema|Diabetic Macular Edema|Diabetic Retinopathy
Interventions: DRUG: Avastin (Bevacizumab)|DRUG: Ozurdex (dexamethasone)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: IL-1-receptor Antagonist During Cephalic Phase of Insulin Secretion in Health and Type 2 Diabetes
Status: RECRUITING
Conditions: Diabetes Mellitus Type 2 in Obese|Inflammation|Metabolic Disease|Glucose Metabolism Disorders (Including Diabetes Mellitus)
Interventions: DRUG: Anakinra Prefilled Syringe
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Electrocoagulation vs. Cold Knife Cutting in Joint Arthroplasty (Electrocoagulation vs Scalpel)
Status: RECRUITING
Conditions: Compassion
Interventions: PROCEDURE: total hip arthroplasty with electrocoagulation|PROCEDURE: total hip arthroplasty without electrocoagulation|PROCEDURE: total knee arthroplasty with electrocoagulation|PROCEDURE: total knee arthroplasty without electrocoagulation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Efficacy of Bevacizumab and Serplulimab Combined With Recombinant Mutant HumanTumor Necrosis Factor(rmhTNF-NC) in the Treatment of Malignant Ascites
Status: RECRUITING
Conditions: Malignant Ascites
Interventions: DRUG: serplulimab|DRUG: Bevacizumab|DRUG: rmhTNF-NC
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety of ALLO-ASC-DFU in the Subjects With Dystrophic Epidermolysis Bullosa
Status: COMPLETED
Conditions: Dystrophic Epidermolysis Bullosa
Interventions: OTHER: Allogeneic mesenchymal stem cells|DEVICE: Polyurethene Film
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of External Drainage of the Lumbar Cistern in Patients With Hydrocephalus Following Meningioma Surgery and Its Influence on Patient Satisfaction
Status: COMPLETED
Conditions: Investigate the Effect of External Lumbar Cistern Drainage in Preventing Postoperative Hydrocephalus in Patients Who Have Undergone Meningioma Surgery
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase I Dose Escalation Study of Single Fraction Ablative Pre-operative Partial Breast (S-PBI) for Early Stage Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer
Interventions: RADIATION: Radiomics on MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pronase Improves Efficacy of Chromoendoscopy Screening on Esophageal Cancer
Status: COMPLETED
Conditions: Esophageal Neoplasms
Interventions: DRUG: Pronase|DRUG: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT