pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Effect of Robotic Treatments on Motor Functions in Subacute Stroke Patients
Status: ENROLLING_BY_INVITATION
Conditions: Stroke
Interventions: OTHER: Learning to walk with a robot|OTHER: Walking group|OTHER: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Initiation of Allopurinol at First Medical Contact for Acute Attacks of Gout
Status: COMPLETED
Conditions: Gout|Gout Acute
Interventions: DRUG: Allopurinol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety, Efficacy, and Pharmacokinetics of ARGX-113 in Patients With Myasthenia Gravis Who Have Generalized Muscle Weakness
Status: COMPLETED
Conditions: Myasthenia Gravis
Interventions: BIOLOGICAL: ARGX-113|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing the Outcome of Cemented All-Polyethylene Pegged vs. Keeled Components Through a Subscapularis Tenotomy or a Subscapularis Peel
Status: COMPLETED
Conditions: Arthropathy Shoulder|Shoulder Pain|Shoulder Osteoarthritis|Shoulder Arthritis|Shoulder Arthropathy Associated With Other Conditions|Necrosis of Bone|Arthritis|Inflammatory Arthritis
Interventions: PROCEDURE: ReUnion TSA, pegged design|PROCEDURE: ReUnion TSA, keeled design
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study to Test Safety and Efficacy of BI456906 in Adults With Non-alcoholic Steatohepatitis (NASH) and Fibrosis (F1-F3)
Status: COMPLETED
Conditions: Non-alcoholic Steatohepatitis (NASH)
Interventions: DRUG: BI 456906|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Revascularization of Renal Artery Stenosis Versus Medical Therapy for the Treatment of Ischemic Nephropathy
Status: UNKNOWN
Conditions: Atherosclerosis|Chronic Kidney Disease|Hypertension, Renovascular|Ischemic Nephropathy|Renal Artery Stenosis
Interventions: DRUG: Medical treatment|PROCEDURE: PTRS|DEVICE: renal artery stent|DEVICE: renal artery stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Validity of 1BPM for Diagnosis of Hypertension
Status: COMPLETED
Conditions: Hypertension
Interventions: DIAGNOSTIC_TEST: 1-hour blood pressure monitoring (1BPM)|DIAGNOSTIC_TEST: 24-hour ambulatory blood pressure monitoring (ABPM)|DIAGNOSTIC_TEST: Office blood pressure measurement (OBPM)|DIAGNOSTIC_TEST: Home blood pressure monitoring (HBPM)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Facilitating Rapid Naltrexone Initiation
Status: ACTIVE_NOT_RECRUITING
Conditions: Opioid Dependence
Interventions: DRUG: CI-581-a|DRUG: CI-581-b
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nasal Naloxone for Narcotic Overdose
Status: UNKNOWN
Conditions: Drug Overdose
Interventions: DRUG: Intranasal (IN) naloxone|DRUG: Intravenous (IV) naloxone|DRUG: Intramuscular (IM) naloxone|DRUG: Intraosseus (IO) naloxone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Study of HOE490 O (Glimepiride and Metformin) Compared With Placebo on Top of Glimepiride
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Metformin|DRUG: placebo|DRUG: Glimepiride (HOE490)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Anlotinib Hydrochloride Capsule Monotherapy and Combination Therapy Relapsed and Refractory Multiple Myeloma
Status: UNKNOWN
Conditions: Multiple Myeloma
Interventions: DRUG: Anlotinib Hydrochloride Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of Dipyridamole in Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder|Schizophreniform Disorder
Interventions: DRUG: Dipyridamole|OTHER: Olanzapine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial to Evaluate the Efficacy of PRM-151 in Subjects With Idiopathic Pulmonary Fibrosis (IPF)
Status: COMPLETED
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: BIOLOGICAL: PRM-151|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: To Demonstrate Similarity of Pharmacokinetics and Evaluate Safety of CT-P16, EU-Approved Avastin and US-licensed Avastin
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: CT-P16|DRUG: EU-approved Avastin|DRUG: US-licensed Avastin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Bortezomib in Treating Patients With Recurrent Glioma
Status: TERMINATED
Conditions: Adult Anaplastic Astrocytoma|Adult Anaplastic Oligodendroglioma|Adult Giant Cell Glioblastoma|Adult Glioblastoma|Adult Gliosarcoma|Recurrent Adult Brain Tumor
Interventions: DRUG: bortezomib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Diagnostic Performance of Electrical Impedance Tomography to Detect Situations at Risk of Lesions Induced by Conventional Mechanical Ventilation in ARDS
Status: COMPLETED
Conditions: Respiratory Distress Syndrome
Interventions: PROCEDURE: ventilatory conditions and measures with scanner and EIT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Focal Laser Ablation for Benign Prostatic Hyperplasia
Status: UNKNOWN
Conditions: Benign Prostatic Hyperplasia|Lower Urinary Tract Symptoms
Interventions: PROCEDURE: Transperineal Focal Laser Ablation (TPLA)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: FT576 in Subjects With Multiple Myeloma
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Myeloma|Myeloma
Interventions: DRUG: FT576 (Allogenic CAR NK cells with BCMA expression)|DRUG: Cyclophosphamide|DRUG: Fludarabine|DRUG: Daratumumab|DRUG: Bendamustine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Skeletal and Dental Changes With Hyrax-type Rapid Maxillary Expander Anchored to Permanent Versus Deciduous Molars
Status: RECRUITING
Conditions: Maxillary Hypoplasia
Interventions: DEVICE: Experimental group|DEVICE: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy and Safety of Heparin-coated Surface-treated Polyacrylonitrile Membrane Hemofilter in Critical Ill CRRT Patients
Status: COMPLETED
Conditions: Critical Ill Patients|Patients Needing Continuous Renal Replacement Therapy
Interventions: DEVICE: AN69ST hemofilter|DEVICE: AN69 hemofilter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Alexa, What is Eliquis and Xarelto?
Status: TERMINATED
Conditions: Patient Engagement|Patient Satisfaction
Interventions: OTHER: Amazon Alexa based voice recording patient education
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Does Antibiotic Prophylaxis at Urinary Catheter Removal Prevent Urinary Tract Infections
Status: ENROLLING_BY_INVITATION
Conditions: Urologic Diseases|Urinary Tract Disease
Interventions: DRUG: Cefuroxime axetil (trimethoprim/sulfamethoxazole if penicillin allergy)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study to Allow Patients Previously Participating in a Novartis Sponsored Trial to Continue Receiving Capmatinib Treatment as Single Agent or in Combination With Other Treatments or the Combination Treatment Alone
Status: RECRUITING
Conditions: Advanced Solid Tumors Which Are cMET-dependent
Interventions: DRUG: Capmatinib|DRUG: Nazartinib|DRUG: Gefitinib|DRUG: Osimertinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of the Sequence of Cardiovascular Genetic Counseling and Testing
Status: ENROLLING_BY_INVITATION
Conditions: Genetic Counseling|Inherited Cardiac Disease
Interventions: BEHAVIORAL: post-test cardiovascular genetic counseling with pre-test education by video|BEHAVIORAL: required phone call with genetic counselor pre-test|BEHAVIORAL: optional phone call with genetic counselor pre-test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: 104RA204 Assessment of the Safety and Efficacy of BG9924 in Rheumatoid Arthritis (RA) Participants
Status: TERMINATED
Conditions: Rheumatoid Arthritis
Interventions: BIOLOGICAL: Baminercept alfa (BG9924)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of a Quadruple Immunosuppressor Regimen With mTOR Inhibitors in Sensitized Kidney Transplant Patients
Status: RECRUITING
Conditions: Disorder Related to Renal Transplantation
Interventions: DRUG: Everolimus|DRUG: standard maintenance immunosuppression
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Dose-Range Finding Study in Participants With Type 2 Diabetes (MK-3102-006)
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Omarigliptin|DRUG: Placebo to omarigliptin|DRUG: Pioglitazone|DRUG: Metformin|DRUG: Placebo to metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Normoglycemia and Neurological Outcome
Status: TERMINATED
Conditions: Acute, Non-traumatic Subarachnoid Hemorrhage|Intraparenchymal Hemorrhage|Brain Injuries
Interventions: DRUG: Insulin|DRUG: Conventional insulin treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Cladribine Dose Escalation in Conditioning Regimen Prior to Allo-HSCT for Refractory Acute Leukemia and Myelodysplastic Syndromes
Status: UNKNOWN
Conditions: Leukemia, Myeloid, Acute|Leukemia, Lymphoblastic, Acute
Interventions: DRUG: Fludarabine-Cladribine-Busulfan conditioning regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fermented Dietary Fiber and Probiotics on Overweight/Obese Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Impaired Glucose Regulation|Overweight and Obesity
Interventions: DIETARY_SUPPLEMENT: dietary fiber probiotic beverages|OTHER: whole grain porridge
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Volume Substitution and Insulin Therapy in Severe Sepsis (VISEP Trial)
Status: COMPLETED
Conditions: Severe Sepsis|Septic Shock
Interventions: DRUG: 10% Hemohes® (10% Hydroxyethyl starch)|DRUG: Sterofundin® (Ringer lactate solution)|DRUG: Actrapid® (Insulin)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Initial Empirical PEEP Setting on the Esophageal Pressure-guided PEEP Titration in ARDS
Status: COMPLETED
Conditions: ARDS, Human|PEEP, Occult|Esophageal and Pleural Pressure
Interventions: OTHER: PEEP adjustment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Low or High Botox Dilution for the Hemiplegic Gait?
Status: RECRUITING
Conditions: Post Stroke Spastic Hemiplegia
Interventions: DRUG: Botulinum toxin|DIAGNOSTIC_TEST: gait analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An Evaluation on a Mental Health Art Exhibition's Impact on Reducing Stigma
Status: NOT_YET_RECRUITING
Conditions: Mental Health Issue
Interventions: OTHER: A mental health art exhibition|OTHER: printed or online education materials
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Flap Thickness Upon Root Coverage With the Use of Acellular Dermal Matrix
Status: COMPLETED
Conditions: Gingival Recession|Periodontal Attachment Loss|Periodontal Diseases|Soft Tissue Injuries
Interventions: PROCEDURE: Mucogingival surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Using the Gate Control Theory of Pain to Decrease Pain During Trigger Finger Corticosteroid Injections
Status: COMPLETED
Conditions: Trigger Finger|Pain
Interventions: BEHAVIORAL: Ipsilateral Scratch Task|BEHAVIORAL: Motor Distraction Task
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Comparing the Efficacy of 14-day Reverse Hybrid Therapy and 14-day Triple Therapy Plus Bismuth Therapy
Status: UNKNOWN
Conditions: Helicobacter Pylori Infection
Interventions: DRUG: triple therapy plus bismuth therapy|DRUG: reverse hybrid therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PAxlovid loNg cOvid-19 pRevention triAl With recruitMent In the Community in Norway
Status: RECRUITING
Conditions: Post COVID-19 Condition, Unspecified|SARS-CoV2 Infection|COVID-19
Interventions: DRUG: Nirmatrelvir/ritonavir|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Impact of Dietary Habits and Nutrition Intervention on Metabolic Syndrome in Individuals With Schizophrenia
Status: COMPLETED
Conditions: Metabolic Syndrome
Interventions: OTHER: Dietary Approaches to Stop Hypertension|OTHER: Nutrition education program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Pharmacokinetics and Pharmacodynamics of TKI258 in Subjects With Acute Myeloid Leukemia
Status: TERMINATED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: TKI258
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Belinostat Combined With Azacitidine/Gemcitabine/Busulfan/Melphalan With Autologous Stem-Cell Transplantation in Refractory or Relapsed Lymphoma
Status: WITHDRAWN
Conditions: Lymphoma
Interventions: DRUG: Busulfan|DRUG: Caphosol|DRUG: Glutamine|DRUG: Pyridoxine|DRUG: Belinostat|DRUG: Azacitidine|DRUG: Gemcitabine|DRUG: Melphalan|PROCEDURE: Stem Cell Transplant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study on the Correlation of Free Vitamin d With BMD and Fracture
Status: UNKNOWN
Conditions: Osteoporosis
Interventions: DIAGNOSTIC_TEST: free vitamin d test|DIAGNOSTIC_TEST: total vitamin d
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Chemotherapy and G-CSF for Mobilization
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: Vinorelbine|DRUG: Gemcitabine|DRUG: G-CSF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharyngeal Sensitivity in Diagnosis Algorithm for Sleep Apnea Syndrome
Status: COMPLETED
Conditions: Sleep Apnea Syndrome
Interventions: DEVICE: Measurement of pharyngeal sensitivity (SENSITEST)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: IBI334 in Subjects With Unresectable, Locally Advanced or Metastatic Solid Tumors
Status: RECRUITING
Conditions: Solid Tumors
Interventions: DRUG: IBI334 D|DRUG: IBI334 C|DRUG: IBI334 A|DRUG: IBI334 B|DRUG: IBI334 F|DRUG: IBI334 E
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Lanabecestat (LY3314814) in Participants With Mild Alzheimer's Disease Dementia
Status: TERMINATED
Conditions: Alzheimer's Disease
Interventions: DRUG: Lanabecestat|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1/2 Multicenter, Randomized, Study to Evaluate the Safety and Efficacy of VS101 Subconjunctival Latanoprost Insert in Subjects With Open-Angle Glaucoma or Ocular Hypertension
Status: COMPLETED
Conditions: Open Angle Glaucoma|Ocular Hypertension
Interventions: DRUG: VS101 Insert Dose A|DRUG: VS101 Insert Dose B|DRUG: VS101 Insert Dose C|DRUG: Latanoprost 0.005% eye drops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Open-label Comparison of 24hr Gastric pH on Days 1, 2, 7 With Once-daily Administration of Lavoltidine 40 mg.
Status: COMPLETED
Conditions: Gastroesophageal Reflux Disease|Reflux, Gastroesophageal
Interventions: DRUG: Lavoltidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy of Phosphatidylserine Enriched With n-3 PUFA Supplementation on ADHD in Children With Epilepsy
Status: COMPLETED
Conditions: Attention Deficit Disorder With Hyperactivity|ADHD Inattention or Mixed Type|Epilepsy|Child
Interventions: DRUG: Vayarin®, supplementation of n-3 PUFA|DRUG: PLACEBO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Insulin Detemir Versus Insulin NPH on Weight Change in Overweight and Obese With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: insulin detemir|DRUG: insulin NPH|DRUG: insulin aspart
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Limbs Range of Motion Exercises Along With Chest Physical Therapy After Correction of Congenital Heart Diseases in ICU
Status: COMPLETED
Conditions: Congenital Heart Disease
Interventions: OTHER: Conventional treatment|OTHER: Limb Range of Motion Exercises + Chest Physical Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Continuation of Serplulimab Plus Chemotherapy After First Progression in Advanced Gastric or Gastro-oesophageal Junction Adenocarcinoma: an Open-label, Randomised Phase II Trial
Status: RECRUITING
Conditions: Gastric Cancer (GC) Gastroesophageal Junction Cancer (GEJ)
Interventions: DRUG: Serplulimab+Paclitaxel+Apatinib|DRUG: Paclitaxel±Ramucirumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Compression Sutures in Controlling Excessive Uterine Bleeding During Caesarean Section
Status: COMPLETED
Conditions: Bleeding in Cesarean Section
Interventions: PROCEDURE: uterine compressive sutures
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Spartan Cube CYP2C19 Inter Laboratory Reproducibilty Study
Status: COMPLETED
Conditions: Genotyping Techniques
Interventions: DEVICE: Spartan Cube CYP2C19 System
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SCREENING
Clinical trial: Clinical Evaluation of Healthy Subjects Receiving Intradermal Saline Using the Microneedle Adapter (Model UAR-2S)
Status: COMPLETED
Conditions: Intradermal Injection
Interventions: DEVICE: Microneedle Adapter (Model UAR-2S)|DEVICE: Hypodermic needle + syringe
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Safety and Tolerability of a Novel Malathion Formulation in Children Age 6-24 Months With Head Lice
Status: COMPLETED
Conditions: Pediculosis
Interventions: DRUG: MALG (malathion) Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Guided ADHD Therapy for Managing the Extent and Severity of Symptoms
Status: COMPLETED
Conditions: ADHD
Interventions: DEVICE: ADHD Therapy|DEVICE: Control Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Controlled Trial of Endoscopic Dilation: Triamcinolone Injection
Status: COMPLETED
Conditions: Dysphagia
Interventions: PROCEDURE: Dilation|OTHER: Triamcinolone Injection|PROCEDURE: Esophagogastroduodenoscopy (EGD)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Erythropoietin Therapy to Induce Regulatory T Cells in Liver Transplant Recipients
Status: ACTIVE_NOT_RECRUITING
Conditions: Liver Transplant Rejection
Interventions: DRUG: Erythropoietin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Biofeedback for Hemianopia Vision Rehabilitation
Status: UNKNOWN
Conditions: Hemianopsia, Homonymous|Brain Injury|Stroke|Brain Tumor|Brain Trauma
Interventions: DEVICE: Biofeedback training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Computer-Based Intervention for Distance Caregivers of Parents With Advanced Cancer
Status: TERMINATED
Conditions: Stage IV Lung Cancer|Malignant Brain Tumor
Interventions: PROCEDURE: Usual care|OTHER: computer-assisted intervention|OTHER: Distress Thermometer|OTHER: Profile of Mood States (POMS-B)|OTHER: Quality of Life: Functional Assessment in Cancer Therapy - (FACT)|OTHER: Tension-Anxiety Subscale
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Oro-nasal Decontamination to Prevent Ventilator-associated Pneumonia
Status: COMPLETED
Conditions: Ventilator Associated Pneumonia
Interventions: DRUG: Povidone-Iodine|DRUG: Saline spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Clinical Study That Will Measure How Well SEP-363856 Works and How Safe it is in Adults With Generalized Anxiety Disorder
Status: RECRUITING
Conditions: Generalized Anxiety Disorder
Interventions: DRUG: SEP-363856|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Linezolid on Ex Vivo Neutrophil and Monocyte Function in Healthy Males
Status: COMPLETED
Conditions: Gram Positive Infection
Interventions: DRUG: linezolid|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Phase II Trial of Concurrent Administration of Intravesical BCG & Interferon in the Treatment and Prevention of Recurrence of Superficial Transitional Carcinoma of the Urinary Bladder
Status: COMPLETED
Conditions: Transitional Carcinoma of Urinary Bladder
Interventions: DRUG: BCG, Interferon
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Involvement of Dipeptidyl Peptidase-4 and Sodium-glucose Co-transporter-2 in Extrapancreatic Glucagon Secretion
Status: COMPLETED
Conditions: Diabetes After Total Pancreatectomy
Interventions: DRUG: Sitagliptin 100mg|DRUG: Empagliflozin 25 MG|OTHER: Placebo tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy & Safety of Loratadine-Betamethasone Oral Solution for Treatment of Severe Perennial Allergic Rhinitis in Children (Study P03428)
Status: COMPLETED
Conditions: Rhinitis
Interventions: DRUG: Loratadine|DRUG: Betamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of PPV+ILM Peeling +/- Subretinal Injection of Ringer Lactate in Management of Nontractional Refractory DME
Status: RECRUITING
Conditions: Efficacy|Safety
Interventions: PROCEDURE: vitrectomy + ILM peeling +/- planned foveal detachment via subretinal injection of ringer's solution.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Adalimumab in the Treatment of Plaque Psoriasis
Status: COMPLETED
Conditions: Plaque Psoriasis
Interventions: BIOLOGICAL: Adalimumab|BIOLOGICAL: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Acupuncture Combined With Nimodipine for Prevention of Post-stroke Dementia
Status: COMPLETED
Conditions: Post-stroke Dementia
Interventions: DRUG: The control group received oral nimodipine tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of More Distal Enteral Bypass After Pancreaticoduodenectomy: A Prospective Multicenter Randomized Clinical Trial
Status: UNKNOWN
Conditions: Pancreaticoduodenectomy|Diabetes
Interventions: PROCEDURE: Pancreaticoduodenectomy with more distal enteral bypass
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Benefit of the Training of the Manual Dexterity Post Stroke.
Status: COMPLETED
Conditions: Cerebral Vascular Accident
Interventions: OTHER: DEXTRAIN|OTHER: CONVENTIONNELLE|OTHER: CONTROLE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nerve Stimulator Versus Ultrasound-guided Interscalene Block for Shoulder Surgery
Status: COMPLETED
Conditions: Pain
Interventions: PROCEDURE: NS-guided interscalene block|PROCEDURE: US-guided interscalene block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of MGD024 in Patients With Relapsed or Refractory Hematologic Malignancies
Status: RECRUITING
Conditions: Leukemia, Acute Myeloid|Myelodysplastic Syndromes|Classical Hodgkin Lymphoma|Leukemia, B-cell|Leukemia, Hairy Cell|Mastocytosis, Aggressive Systemic|Blastic Plasmacytoid Dendritic Cell Neoplasm|Chronic Myeloid Leukemia
Interventions: DRUG: MGD024
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Materno-fetal Consequences of Symptomatic Dengue in Pregnant Wowen in French Guiana
Status: COMPLETED
Conditions: Dengue|Pregnancy Preterm|Women|Fever|Parturition; Precipitate|Infant, Newborn
Interventions: OTHER: Biological sampling and collection (serum)|OTHER: Biological sampling and collection (placenta)|OTHER: Questionnaire|OTHER: Data collection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Docetaxel, Cisplatin and Fluorouracil in Treating Patients With Previously Untreated Stage II-IV Nasal Cavity and Paranasal Sinus Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Locally Advanced Nasal Cavity and Paranasal Sinus Squamous Cell Carcinoma|Nasal Cavity and Paranasal Sinus Poorly Differentiated Carcinoma|Sinonasal Undifferentiated Carcinoma|Stage II Nasal Cavity and Paranasal Sinus Cancer AJCC v8|Stage III Nasal Cavity and Paranasal Sinus Cancer AJCC v8|Stage IVA Nasal Cavity and Paranasal Sinus Cancer AJCC v8|Stage IVB Nasal Cavity and Paranasal Sinus Cancer AJCC v8
Interventions: DRUG: Carboplatin|OTHER: Chemoradiotherapy|DRUG: Cisplatin|PROCEDURE: Definitive Surgical Resection|DRUG: Docetaxel|DRUG: Fluorouracil|PROCEDURE: Quality-of-Life Assessment|RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preliminary Study to Investigate the Effect of rTMS and SSRI Antidepressants on Leukocyte Expression of the C-FOS and DUSP1 Genes in Patients Treated for Depression
Status: TERMINATED
Conditions: Depression
Interventions: DEVICE: rTMS|DRUG: SSRI (SEROPLEX ou ZOLOFT)|OTHER: Genetic samples
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Impact of Onco-sexology Support on the Quality of Life of Patients Newly Diagnosed for Cancer
Status: NOT_YET_RECRUITING
Conditions: Cancer
Interventions: OTHER: Onco-sexology support|OTHER: Onco-sexology support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Two-dimensional Shear-Wave Elastography Evaluate Esophageal Varices Bleeding Risk of Liver Cirrhosis
Status: UNKNOWN
Conditions: Liver Cirrhosis|Esophageal Varices|Liver Stiffness
Interventions: DIAGNOSTIC_TEST: Gastroscopy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Bedside Genetic or Pharmacodynamic Testing to Prevent Periprocedural Myonecrosis During PCI (ONSIDE TEST)
Status: UNKNOWN
Conditions: Stable Angina
Interventions: DEVICE: Genotyping|DEVICE: Phenotyping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Assessment With Gait Analysis of Robotic Total Knee Arthroplasty Using Inverse Kinematic Alignment
Status: ACTIVE_NOT_RECRUITING
Conditions: Osteoarthritis, Knee
Interventions: PROCEDURE: Robotically Assisted Total Knee Arthroplasty - Knee Replacement
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Radio Guided Lymph Node Dissection in Oligometastatic Prostate Cancer Patients
Status: UNKNOWN
Conditions: Prostate Cancer|Lymph Node Metastases
Interventions: PROCEDURE: Radio guided surgery (RGS) using Indium-labelled PSMA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparison Of Outcome Of Antibiotic Coated Vicryl Vs Non-Coated Vicryl In Abdominal Fascial Closure After Laparotomy In Children
Status: COMPLETED
Conditions: Surgical Site Infection
Interventions: PROCEDURE: antibiotic coated vicryl used for fascial closure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: The Pilot Experimental Study of the Neuroprotective Effects of Exosomes in Extremely Low Birth Weight Infants
Status: NOT_YET_RECRUITING
Conditions: Premature Birth|Extreme Prematurity|Preterm Intraventricular Hemorrhage|Hypoxia-Ischemia, Cerebral|Neurodevelopmental Disorders
Interventions: OTHER: Exosomes derived from mesenchymal stromal cells (MSCs)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Study of the Combination of Oxaliplatin, Capecitabine, and Trastuzumab With Chemoradiotherapy in the Adjuvant Setting in Operated Participants With Human Epidermal Growth Factor Receptor-2 Positive (HER2+) Gastric or Gastroesophageal Junction Cancer
Status: COMPLETED
Conditions: Gastric Cancer|Gastroesophageal Junction Cancer
Interventions: DRUG: Oxaliplatin|RADIATION: Radiation|DRUG: Capecitabine|DRUG: Trastuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assisted Fluid Management in Patients Undergoing Major Abdominal and Orthopedic Surgery
Status: WITHDRAWN
Conditions: Goal Directed Fluid Therapy
Interventions: OTHER: Use of a decision support system on the EV1000 monitor (AFM mode)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Hyperoxia on Ventilation During Recovery From General Anesthesia
Status: RECRUITING
Conditions: Ventilatory Depression|Postoperative Respiratory Failure
Interventions: OTHER: Oxygen Gas for Inhalation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pharmacokinetics, Safety, Tolerability and Pharmacodynamics of BMS-986189 in Healthy Subjects
Status: COMPLETED
Conditions: Severe Sepsis
Interventions: DRUG: BMS-986189|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Assess the Pulmonary Distribution of Budesonide, Glycopyrronium and Formoterol Fumarate
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: BGF MDI (budesonide, glycopyrronium and formoterol fumarate) with 10 s breath hold|DRUG: BGF MDI ((budesonide, glycopyrronium and formoterol fumarate) with 3 s breath hold
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Photodynamic Therapy During Supportive Periodontal Therapy
Status: COMPLETED
Conditions: Periodontal Diseases|Chronic Periodontitis|Periodontal Attachment Loss
Interventions: DEVICE: Fotosan 630, CMS Dental, Copenhagen, Denmark|OTHER: Scaling and root planing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Open Comparative Study of the Effectiveness and Incomparable Study of the Immunogenicity and Safety of the Vaccine (CoviVac) for Adults Aged 60 Years and Older
Status: ACTIVE_NOT_RECRUITING
Conditions: Corona Virus Infection|Vaccine|COVID-19
Interventions: BIOLOGICAL: CoviVac vaccine (inactivated whole-virion concentrated purified) manufactured by FSBSI "Chumakov FSC R&D IBP RAS"
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Trial of GM-CSF Given in Combination With Ketoconazole and Mitoxantrone in Patients With Progressive Prostate Cancer
Status: TERMINATED
Conditions: Prostatic Neoplasms
Interventions: DRUG: GM-CSF|DRUG: Ketoconazole|DRUG: Mitoxantrone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Medication Development in Alcoholism: Investigating PPAR Agonists
Status: COMPLETED
Conditions: Alcoholism
Interventions: DRUG: Sugar Pill|DRUG: TRICOR (fenofibrate)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Phase 3 Study of Tislelizumab Versus Sorafenib in Participants With Unresectable HCC
Status: COMPLETED
Conditions: Hepatocellular Carcinoma (HCC)
Interventions: DRUG: Tislelizumab|DRUG: Sorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectivenes of Cyanoacrylate (Glubran 2®) in Reducing Seroma Formation in Breast Cancer Patients Post-Axillary Dissection
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: DEVICE: Glubran 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: The Scandinavian AED and Mobile Bystander Activation Trial
Status: COMPLETED
Conditions: Out-Of-Hospital Cardiac Arrest|Cardiac Arrest, Sudden
Interventions: DEVICE: Layperson allocated to start CPR and fetch nearest AED|DEVICE: Layperson allocated to start CPR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Safety and Efficacy of the ExcelTM Sirolimus Eluting Stent With a Biodegradable Polymer Versus Sirolimus Eluting Stent With Non-Biodegradable Polymer in the Treatment of Patients With de Novo Coronary Artery Lesions
Status: UNKNOWN
Conditions: Ischemia|Cardiac Death|Myocardial Infarction
Interventions: DEVICE: Percutaneous Transluminal Coronary Angioplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of Powered Exoskeleton Use for Gait Rehabilitation in Individuals With Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis|Gait Disorders, Neurologic
Interventions: DEVICE: Ekso GT™ exoskeleton
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Real World Study on the Efficacy and Safety of Apremilast in Chinese Patients With Moderate to Severe Plaque Psoriasis, a Multi Center, Prospective, Observational Trial（REACT）
Status: NOT_YET_RECRUITING
Conditions: Psoriasis
Interventions: DRUG: Apremilast
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Trial to Determine the Maximum Tolerated Dose of Genexol-PM Plus Gemcitabine and Evaluate Efficacy and Safety of Genexol-PM Regimens in Subjects With Advanced Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DRUG: Genexol-PM
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: Lingual Endurance Exercise in Treating Post-Stroke Dysphagia
Status: COMPLETED
Conditions: Dysphagia, Oral Phase|Stroke, Ischemic
Interventions: OTHER: Lingual Endurance Exercise|OTHER: Lingual Endurance + Transference Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Percutaneous Electrical Nerve Stimulation Compared to Passive Assisted Neurodynamics in Brachial Plexus Neuropathy
Status: UNKNOWN
Conditions: Percutaneous Electrical Nerve Stimulation|Peripheral Neuropathy|Neuropathic Pain
Interventions: PROCEDURE: Percutaneous Electrical Nerve Stimulation|PROCEDURE: Neurodynamic and manual therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Efficacy and Pharmacokinetics of ThisCART19A in Patients With Refractory or Relapsed B Cell Lymphoma
Status: NOT_YET_RECRUITING
Conditions: Allogeneic, CAR-T, Protein Sequestration, Non-gene Edited, r/r B-NHL
Interventions: DRUG: ThisCART19A
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CHAMP: A Randomized Controlled Trial of High-intensity Aerobic and Resistance Exercise for Metastatic Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: BEHAVIORAL: Experimental: Arm 1 (Aerobic Exercise)|BEHAVIORAL: Experimental: Arm 2 (Resist. Exercise)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Postoperative Hepatic Arterial Chemotherapy in High-risk Patients as Adjuvant Treatment After Resection of Colorectal Liver Metastases
Status: SUSPENDED
Conditions: Colorectal Cancer
Interventions: DRUG: Oxaliplatin HAI|DRUG: Oxaliplatin IV|DRUG: mFOLFOX6|DRUG: LV5FU2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chronic Kidney Disease and Heart Failure With Preserved Ejection Fraction: The Role of Mitochondrial Dysfunction
Status: COMPLETED
Conditions: Renal Insufficiency, Chronic|Heart Failure With Preserved Ejection Fraction
Interventions: DIETARY_SUPPLEMENT: MitoQ|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: PROximal Protection VErsus NON-Protection in Carotid Artery Stenting
Status: UNKNOWN
Conditions: Carotid Artery Stenosis
Interventions: PROCEDURE: Carotid Artery Stenting with Proximal Protection|PROCEDURE: Carotid Artery Stenting without Protection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Comparing the Combination Domvanalimab and Zimberelimab With Pembrolizumab in Untreated Locally Advanced or Metastatic PD-L1-High Non-Small Cell Lung Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Non Small Cell Lung Cancer|Nonsquamous Non Small Cell Lung Cancer|Squamous Non Small Cell Lung Cancer|Lung Cancer
Interventions: DRUG: Domvanalimab|DRUG: Zimberelimab|DRUG: Carboplatin|DRUG: Paclitaxel|DRUG: Pemetrexed|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study on the Safety and Immune Response of AS37 Together With Hepatitis B Antigen in Adults Aged 18-45 Years
Status: ACTIVE_NOT_RECRUITING
Conditions: Hepatitis B
Interventions: COMBINATION_PRODUCT: GSK's Hepatitis B vaccine adjuvanted with aluminum hydroxide|BIOLOGICAL: GSK's HBsAg candidate vaccine adjuvanted with GSK's AS03 adjuvant system|BIOLOGICAL: GSK's Hepatitis B vaccine adjuvanted with GSK's AS04 adjuvant system|BIOLOGICAL: GSK's HBsAg vaccine adjuvanted with GSK's AS37 adjuvant system formulation 1|BIOLOGICAL: GSK's HBsAg vaccine adjuvanted with GSK's AS37 adjuvant system formulation 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of Dovitinib in Patients With Gastrointestinal Stromal Tumors Refractory and/or Intolerant to Imatinib
Status: COMPLETED
Conditions: Gastrointestinal Stromal Tumors
Interventions: DRUG: Dovitinib (TKI258)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to EXhibit Percutaneous Coronary Artery Dilatation With Non-Slip Element Balloon
Status: COMPLETED
Conditions: Coronary Stenosis|Coronary Artery Stenosis|In-stent Restenosis
Interventions: DEVICE: Lacrosse NSE ALPHA coronary dilatation catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single-dose Potassium Supplementation in Patients With ADHD for Whom the Anesthetic Lidocaine is Ineffective
Status: UNKNOWN
Conditions: ADHD
Interventions: DRUG: Potassium Gluconate Oral Capsule|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Antioxidants on Skin Blood Flow-BH4
Status: COMPLETED
Conditions: Cardiovascular Diseases|Cardiovascular Risk Factor|Vasoconstriction
Interventions: DRUG: Control: Lacated Ringers|DRUG: Apocynin|DRUG: Allopurinol|DRUG: BH4|DRUG: NG Nitro L Arginine Methyl Ester|DRUG: Sodium Nitroprusside|DRUG: Acetyl-ß-methylcholine chloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Skeletal Muscle Hypertrophy and Cardio-Metabolic Benefits After Spinal Cord Injury
Status: COMPLETED
Conditions: Spinal Cord Injuries
Interventions: DEVICE: NMES+FES|DEVICE: Control+FES
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH