pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Study Into the Effect of Ibandronate for the Treatment of Bone Marrow Edema in Relation to Spontaneous or Non-traumatic Osteonecrosis of the Knee: A Randomized Double-blind, Placebo-controlled Trial
Status: COMPLETED
Conditions: Osteonecrosis of the Knee|Bone Marrow Edema of the Knee
Interventions: DRUG: Ibandronate IV|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bladder Drainage During Labor: A Randomized Controlled Study of Obstetric Foley Therapy
Status: COMPLETED
Conditions: Labor
Interventions: PROCEDURE: Indwelling catheter|PROCEDURE: Intermittent straight catheterization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Total-Body Irradiation and Fludarabine Phosphate Followed by Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies or Kidney Cancer
Status: COMPLETED
Conditions: Adult Acute Myeloid Leukemia in Remission|Childhood Acute Lymphoblastic Leukemia in Remission|Childhood Acute Myeloid Leukemia in Remission|Childhood Myelodysplastic Syndrome|Childhood Renal Cell Carcinoma|Chronic Myelomonocytic Leukemia|Clear Cell Renal Cell Carcinoma|de Novo Myelodysplastic Syndrome|Metastatic Renal Cell Cancer|Previously Treated Myelodysplastic Syndrome|Progression of Multiple Myeloma or Plasma Cell Leukemia|Recurrent Adult Acute Lymphoblastic Leukemia|Recurrent Adult Acute Myeloid Leukemia|Recurrent Adult Hodgkin Lymphoma|Recurrent Adult Lymphoblastic Lymphoma|Recurrent Adult Non-Hodgkin Lymphoma|Recurrent Childhood Acute Lymphoblastic Leukemia|Recurrent Childhood Acute Myeloid Leukemia|Recurrent Childhood Lymphoblastic Lymphoma|Recurrent Childhood Non-Hodgkin Lymphoma|Refractory Anemia|Refractory Anemia With Ringed Sideroblasts|Refractory Childhood Hodgkin Lymphoma|Refractory Chronic Lymphocytic Leukemia|Renal Medullary Carcinoma|Type 1 Papillary Renal Cell Carcinoma|Type 2 Papillary Renal Cell Carcinoma|Untreated Adult Acute Lymphoblastic Leukemia|Untreated Adult Acute Myeloid Leukemia|Untreated Childhood Acute Lymphoblastic Leukemia
Interventions: DRUG: Fludarabine Phosphate|RADIATION: Total-Body Irradiation|PROCEDURE: Peripheral Blood Stem Cell Transplantation|PROCEDURE: Nonmyeloablative Allogeneic Hematopoietic Stem Cell Transplantation|DRUG: Cyclosporine|DRUG: Mycophenolate Mofetil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Abiraterone Acetate Plus ADT Versus APALUTAMIDE Versus Abiraterone and APALUTAMIDE in Patients With Advanced Prostate Cancer With Non-castrate Testosterone Levels
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: Apalutamide|DRUG: Abiraterone|DRUG: ADT|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating the Safety,Tolerability, PK and PD of SAM-531 in the Subjects With Mild to Moderate Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer Disease
Interventions: DRUG: SAM-531|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Long Term Safety and Efficacy of Butterfly Medical Prostatic Retraction Device in Benign Prostatic Hyperplasia (BPH) Patients Who Completed 12 Months of Follow-Up Post Implantation (Continuation Study for Study BM-011-IL)
Status: RECRUITING
Conditions: BPH|BOO - Bladder Outflow Obstruction|Enlarged Prostate (BPH)
Interventions: PROCEDURE: Butterfly Medical Prostatic Retraction Device ("the Butterfly device") removal/replacement
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Symptoms Comparison: Suture-stent vs Conventional Double-J Stents After Ureterorenoscopy. A Prospective Randomized Trial
Status: COMPLETED
Conditions: Symptoms and Signs|Pain|Ureteral Calculi
Interventions: OTHER: Administration of USSQ Symptoms questionnaire after stent positioning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Phase II Randomized Open Label Study of KLH-2109 in Patients With Endometriosis
Status: COMPLETED
Conditions: Endometriosis
Interventions: DRUG: KLH-2109|DRUG: KLH-2109
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Duloxetine and Venlafaxine on the Pharmacokinetics and Pharmacodynamics of Oral Tramadol: A Three-phase Randomized Balanced Cross-over Study in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Placebo|DRUG: Duloxetine|DRUG: Venlafaxine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Feasibility of Motor-cognitive Home Training for Parkinson's Disease Using eHealth Technology
Status: COMPLETED
Conditions: Idiopathic Parkinson Disease|Telerehabilitation|Physical Therapy
Interventions: OTHER: Motor-cognitive exercise therapy in the home
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Paclitaxel, Carboplatin and Cetuximab (PCC) With Cetuximab, Docetaxel, Cisplatin and Fluorouracil (C-TPF) in Previously Untreated Patients With Locally Advanced Head and Neck Squamous Cell Carcinoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Head and Neck Squamous Cell Carcinoma
Interventions: DRUG: Paclitaxel|DRUG: Carboplatin|DRUG: Cetuximab|DRUG: Docetaxel|DRUG: Cisplatin|DRUG: Fluorouracil|RADIATION: Radiotherapy (RT)|OTHER: Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Decision Support for Intraoperative Low Blood Pressure
Status: COMPLETED
Conditions: Hypotension
Interventions: PROCEDURE: Attending real-time decision support|PROCEDURE: In-room real-time decision support|PROCEDURE: Attending feedback emails|PROCEDURE: In-room provider feedback emails|DEVICE: Anesthesia Information Management System (AIMS)|DEVICE: Perioperative Data Warehouse (PDW)|PROCEDURE: General anesthesia|DEVICE: Pager system|PROCEDURE: Central neuraxial anesthesia|PROCEDURE: Non-cardiac surgery|DRUG: Propofol|DRUG: Sevoflurane|DRUG: Desflurane|DRUG: Isoflurane|DRUG: Ephedrine|DRUG: Phenylephrine|DRUG: Norepinephrine|DRUG: Epinephrine|DRUG: Dobutamine|DRUG: Dopamine|DRUG: Isoproterenol|DRUG: Milrinone|DRUG: Atropine|DRUG: Glycopyrrolate|DRUG: Vasopressin|DRUG: Terlipressin|DRUG: Sodium Chloride 0.9%|DRUG: Ringer's lactate|DRUG: Hydroxyethyl starch solutions|DRUG: Fresh Frozen Plasma|DRUG: Packed Red Blood Cells|DRUG: Albumin solutions|DRUG: Plasma-Lyte|DRUG: Lidocaine|DRUG: Bupivacaine|DRUG: Levobupivacaine|DRUG: Ropivacaine|DRUG: Mepivacaine|DRUG: Tetracaine|DRUG: Prilocaine|DRUG: Procaine|DRUG: Chloroprocaine|DRUG: Benzocaine|DRUG: Articaine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Cognitive Therapy to Improve Word Finding
Status: COMPLETED
Conditions: Anomia|Aphasia|Traumatic Brain Injury|Cerebrovascular Accident
Interventions: PROCEDURE: Errorful training condition|PROCEDURE: Errorless training condition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: First-in-human Study to Evaluate Safety, Tolerability, and Pharmacokinetics of Single and Multiple Ascending Doses of CC-90001
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: CC-90001|DRUG: CC-90001|DRUG: CC-90001|DRUG: CC-90001|DRUG: CC-90001|DRUG: CC-90001|DRUG: CC-90001|DRUG: CC-90001|DRUG: CC-90001|DRUG: CC-90001|DRUG: Placebo|DRUG: CC-90001|DRUG: CC-90001|DRUG: CC-90001
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Carotid Plaque Characteristics by MRI in AIM-HIGH (Carotid MRI Substudy)
Status: COMPLETED
Conditions: Coronary Artery Disease|Carotid Artery Diseases|Atherosclerosis
Interventions: DRUG: Simvastatin, simvastatin plus extended-release niacin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety & Initial Efficacy of the LunGuard PFT Sys. on Enteral-Fed, Sedated and Mechanically Ventilated Patients Peristaltic Feeding Tube
Status: UNKNOWN
Conditions: Gastro-esophageal Reflux
Interventions: DEVICE: Peristaltic Feeding Tube|DEVICE: ConvaTec Levin Duodenal Tube
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of Different Operations for Siewert Type II Adenocarcinoma of Esophagogastric Junction
Status: RECRUITING
Conditions: Siewert Type II Adenocarcinoma of Esophagogastric Junction
Interventions: PROCEDURE: Endoscopy Ivor-lewis|PROCEDURE: Laparoscopic transabdominal enlarged gastrectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Meta-analyses of Total and Individual Fructose-containing Sugars and Incident Cardiometabolic Disease
Status: UNKNOWN
Conditions: Overweight|Obesity|Dyslipidemia|Hyperlipidemia|Diabetes|Prediabetes|Dysglycemia|Gout|Hypertension|Metabolic Syndrome|Coronary Heart Disease|Cardiovascular Disease
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Continued, Long-Term Follow-Up and Lenalidomide Maintenance Therapy for Patients on BMT CTN 0702 Protocol (BMT CTN 07LT)
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BoneFit: Multimodal Prehabilitation for People Preparing for Orthopaedic Surgery
Status: RECRUITING
Conditions: Orthopedic Disorder
Interventions: BEHAVIORAL: Experimental: BoneFit intervention|BEHAVIORAL: Placebo Comparator: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Netarsudil Use After Descemtorhexis Without Endothelial Keratoplasty
Status: COMPLETED
Conditions: Fuchs' Endothelial Dystrophy
Interventions: DRUG: Netarsudil Ophthalmic
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Drug Interaction Study of the Effect of Apixaban on the PK of Digoxin in Healthy Subjects
Status: COMPLETED
Conditions: N/A - Healthy Subjects
Interventions: DRUG: Apixaban|DRUG: Digoxin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: SB-715992 In Combination With Docetaxel In Patients With Solid Tumors
Status: COMPLETED
Conditions: Solid Tumor Cancer
Interventions: DRUG: docetaxel|DRUG: SB-715992
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Enoblituzumab Plus MGA012 or MGD013 in Squamous Cell Carcinoma of the Head and Neck
Status: WITHDRAWN
Conditions: Head and Neck Cancer|Squamous Cell Carcinoma of Head and Neck
Interventions: BIOLOGICAL: enoblituzumab|BIOLOGICAL: MGA012|BIOLOGICAL: MGD013
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: VR Therapy for Psychosis Negative Symptoms (V-NeST)
Status: UNKNOWN
Conditions: Psychosis|Schizophrenia
Interventions: BEHAVIORAL: Virtual Reality Therapy (V-NeST)|OTHER: Treatment as Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Prospective Controlled Treatment Trial for Post-Traumatic Headaches
Status: ACTIVE_NOT_RECRUITING
Conditions: Post-Traumatic Headaches
Interventions: DRUG: Occipital Nerve Block (ONB) using lidocaine and dexamethosone|DRUG: Cervical Medial Branch Block (CMBB) using lidocaine and dexamethosone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: DIabetic Retinopathy Candesartan Trials.
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: DRUG: candesartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Oxidized Omega-3 Supplements With Different Oxidation
Status: COMPLETED
Conditions: Overweight
Interventions: DIETARY_SUPPLEMENT: Less oxidized oil and diet|DIETARY_SUPPLEMENT: More oxidized oil and diet|DRUG: Hypercholesterolemic diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: FREEOAB Study for Overactive Bladder
Status: COMPLETED
Conditions: Overactive Bladder|Urinary Frequency|Urinary Incontinence, Urge|Urinary Urgency
Interventions: DEVICE: Wearable Bladder Modulation System-1x per week|DEVICE: Wearable Bladder Modulation System - 3x per week
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility of an Adapted Physical Activity Program for Patients Treated With an Autograft (APA²)
Status: RECRUITING
Conditions: Myeloma|Lymphoma|Autologous Transplant
Interventions: OTHER: Adapted Physical Activity
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Vosaroxin and Decitabine in Older Patients With Acute Myeloid Leukemia and High-risk Myelodysplastic Syndrome
Status: COMPLETED
Conditions: Leukemia
Interventions: DRUG: Vosaroxin|DRUG: Decitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cross-cultural Adaptation and Validity of the Arabic-translated NEUROPATHY-SPECIFIC QUALITY OF LIFE Questionnaire
Status: RECRUITING
Conditions: Diabetic Neuropathies|Diabetic Peripheral Neuropathy
Interventions: DIAGNOSTIC_TEST: Neuropathy - and Foot Ulcer - Specific Quality of Life instrument (Neuro Qol)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Tranexamic Acid for Total Knee Arthroscopy
Status: COMPLETED
Conditions: Blood Loss, Surgical
Interventions: DRUG: Tranexamic acid (TXA)|DRUG: Placebo Normal Saline (NS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Gemcitabine and Capecitabine in Patients With Advanced Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DRUG: Capecitabine (Xeloda)|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Efficacy and Tolerability of Etoricoxib Monotherapy Versus Combination Oxycodone-etoricoxib in Moderate to Severe Pain From Chronic Low Back Pain
Status: UNKNOWN
Conditions: Low Back Pain
Interventions: DRUG: etoricoxib|DRUG: oxycodone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: TMS and Body Image Treatment for Anorexia Nervosa
Status: RECRUITING
Conditions: Anorexia Nervosa
Interventions: DEVICE: Transcranial magnetic stimulation|BEHAVIORAL: Body Image Intervention|BEHAVIORAL: Treatment as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of Taxol, Carboplatin, and Bevacizumab in Advanced Stage Ovarian Carcinoma Patients
Status: COMPLETED
Conditions: Ovarian Neoplasms
Interventions: DRUG: Avastin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Online Education Programme for People With Type 1 Diabetes and Suboptimal Metabolic Control
Status: RECRUITING
Conditions: Diabetes Mellitus, Type I
Interventions: BEHAVIORAL: Online education programme|BEHAVIORAL: Standard education programme
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of the Efficacy and Safety of Two Low-concentration Atropine Sulfate Eye Drops
Status: ACTIVE_NOT_RECRUITING
Conditions: Myopia
Interventions: DRUG: Lower dose atropine sulfate eye drops|DRUG: Low dose atropine sulfate eye drops|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing Virtual Reality Therapy With Modified-CIMT Versus Modified-CIMT Alone in Hemiparetic Children
Status: UNKNOWN
Conditions: Hemiparesis
Interventions: OTHER: Virtual Reality Therapy|OTHER: mCIMT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Determining the Complete Protection Time of an Insect Repellent With 30% Citriodiol® Against Three Species of Ticks.
Status: COMPLETED
Conditions: Tick Bites
Interventions: OTHER: Citrepel (Insect Repellent) EPA Reg. No. 84878-2
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of Sirolimus for Injection (Albumin-bound) in Patients With Advanced Solid Tumors
Status: NOT_YET_RECRUITING
Conditions: Malignant Solid Tumors
Interventions: DRUG: Sirolimus for Injection (Albumin-bound)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study for Sedation Interruption in Children
Status: UNKNOWN
Conditions: Daily Sedative Interruption|Sedation Strategies|Sedation Protocols|Mechanical Ventilation|Sedation
Interventions: OTHER: Sedation Interruption Protocol|OTHER: Standard Sedation Protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Prevention of Coronary Aneurysms in Kawasaki Syndrome
Status: COMPLETED
Conditions: Cardiovascular Diseases|Coronary Aneurysm|Heart Diseases|Mucocutaneous Lymph Node Syndrome
Interventions: DRUG: immunoglobulins, intravenous|DRUG: aspirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: |Primary Purpose: PREVENTION
Clinical trial: QL1706 Monotherapy or in Combination With Bevacizumab and XELOX as First-line Treatment of Unresectable Advanced or Metastatic CRC
Status: RECRUITING
Conditions: Colorectal Carcinoma
Interventions: DRUG: QL1706|DRUG: Bevacizumab|DRUG: Oxaliplatin injection|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ibandronate or Zoledronate in Treating Patients With Newly Diagnosed Bone Metastases From Breast Cancer
Status: UNKNOWN
Conditions: Breast Cancer|Hypercalcemia of Malignancy|Metastatic Cancer
Interventions: DRUG: ibandronate sodium|DRUG: zoledronic acid|DRUG: Zolendronic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acupuncture for Reduction of Inflammation
Status: COMPLETED
Conditions: Thyroid or Parathyroid Surgery
Interventions: DEVICE: acupuncture|DEVICE: no acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Study of PDVF and Polypropylene Transobturator Suburethral Tapes
Status: COMPLETED
Conditions: Urinary Stress Incontinence
Interventions: DEVICE: PVDF transobturator tape|DEVICE: Polypropylene transobturator tape
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adductor Canal Block Versus Femoral Block on Pain and Quadriceps Strength
Status: COMPLETED
Conditions: Anterior Cruciate Ligament Tear|Knee Meniscus Tear
Interventions: PROCEDURE: Femoral Nerve Block|PROCEDURE: Adductor Canal Nerve Block|DRUG: preoperative Femoral Nerve Block using 20ml of 0.5% ropivacaine|DRUG: Preoperative Adductor canal block with 0.75%% ropivacaine 13.3ml.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Bioskin Ten-7 vs. Standard Treatment on Patient Reported Outcomes and Cytokine.
Status: COMPLETED
Conditions: Osteoarthritis of the Knee
Interventions: DRUG: Standard treatment only|DEVICE: Standard treatment plus Bioskin Ten-7 knee brace
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Atorvastatin and Lifestyle Intervention on Progression of Pre-Clinical Atherosclerosis
Status: UNKNOWN
Conditions: Atherosclerosis
Interventions: DRUG: Atorvastatin|BEHAVIORAL: Aggressive lifestyle intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Visual Function Change in Wet Age-related Macular Degeneration Patients With Better Baseline Visual Acuity
Status: COMPLETED
Conditions: Age-Related Macular Degeneration
Interventions: DRUG: Aflibercept Injection [Eylea]
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SPI-2012 vs Pegfilgrastim in the Management of Neutropenia in Participants With Breast Cancer With Docetaxel and Cyclophosphamide (ADVANCE)
Status: COMPLETED
Conditions: Neutropenia|Breast Cancer
Interventions: DRUG: SPI-2012|DRUG: Pegfilgrastim|DRUG: Docetaxel|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Combined Immunization With Live Attenuated Varicella Vaccine and Inactivated Hepatitis A Vaccine
Status: COMPLETED
Conditions: Varicella
Interventions: BIOLOGICAL: The live attenuated varicella vaccine and the inactivated hepatitis A vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Assessment of Platelet-Rich Fibrin and Topical Ozonated Oil in the Management of Palatal Wound Healing After Free Gingival Graft Harvest
Status: COMPLETED
Conditions: Inadequately Attached Gingiva (Disorder)
Interventions: DRUG: ozonated oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect on Non-Alcoholic Fatty Liver Disease in Patients With Type 2 Diabetes Mellitus With Gastric Inhibitory Polypeptide/Glucagon Like Peptide-1 Analogue
Status: RECRUITING
Conditions: Non-Alcoholic Fatty Liver Disease|Non-alcoholic Steatohepatitis|Type 2 Diabetes|Liver Fat
Interventions: DRUG: GIP/GLP-1a
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Response Monitoring Trial in Patients With Suspected Recurrence of Glioblastoma
Status: TERMINATED
Conditions: Glioma|Glioblastoma|Glioblastoma Multiforme
Interventions: DRUG: FDOPA PET
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Vitamin Therapy in JGH Patients
Status: COMPLETED
Conditions: Patients With Hypovitaminosis C and D|Vitamin Deficiencies
Interventions: DIETARY_SUPPLEMENT: vitamin C or vitamin D
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Beta-blockade on Platelet Aggregation in Acute Coronary Syndrome
Status: COMPLETED
Conditions: Acute Coronary Syndrome
Interventions: DRUG: Carvedilol|DRUG: Metoprolol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of the Safety of BEMA™ Fentanyl Use for Breakthrough Pain in Cancer Subjects on Chronic Opioid Therapy
Status: COMPLETED
Conditions: Pain|Cancer
Interventions: DRUG: BEMA Fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Application of Warm Water and Warm Salt Water to Patients With Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis - Rheumatism
Interventions: OTHER: warm salt water bath
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy, Local Tolerance and Patient Acceptability of a Moisturizing Emollient in Patients With Uremic Xerosis
Status: COMPLETED
Conditions: Uremic Xerosis
Interventions: DRUG: V0034 CR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Randomized Controlled Trial on Brief Behavioral Parent Training
Status: RECRUITING
Conditions: Disruptive Behavior|Behavior Problems|Behavioral Problems|Problem Behaviors|Behavioral Symptoms|Behavioral Difficulties
Interventions: BEHAVIORAL: Brief behavioral parent training with optional booster sessions|BEHAVIORAL: Care as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 2A Study to Evaluate the Safety and Effect on Exercise Challenge Testing of MEDI-528 in Adults With Asthma
Status: TERMINATED
Conditions: Asthma
Interventions: BIOLOGICAL: MEDI528 50 mg|OTHER: PLACEBO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Gemcitabine Plus Erlotinib Versus Erlotinib Plus Gemcitabine Plus Oxaliplatin, in Pancreatic Cancer
Status: TERMINATED
Conditions: Pancreatic Cancer
Interventions: DRUG: Gemcitabine|DRUG: Gemcitabine|DRUG: Erlotinib|DRUG: Oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of IntraArticular Platelet-Rich-Plasma to Corticosteroid Injections for Patients With Zygapophyseal Joint (Z-Joint) Low Back Pain Confirmed by Dual Intra-Articular Local Anesthetic Injections
Status: COMPLETED
Conditions: Low Back Pain|Platelet Rich Plasma|Zygapophyseal Joint Arthritis
Interventions: PROCEDURE: PRP - platelet rich plasma injection|PROCEDURE: Cortisone injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Platelet-rich Plasma (PRP) Injection for Treatment of Erectile Function
Status: COMPLETED
Conditions: Erectile Dysfunction Due to Arterial Insufficiency
Interventions: BIOLOGICAL: Platelet-Rich Plasma (PRP)|BIOLOGICAL: Normal saline injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Change in Quality of Life After Addition of Weekly 40 mg Pegvisomant/Placebo in Controlled Acromegalic Patients
Status: COMPLETED
Conditions: Quality of Life|Acromegaly
Interventions: DRUG: Pegvisomant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study of the Combination of Pembrolizumab and ATRA Combination Treatment of Relapsed HL and B-NHL
Status: RECRUITING
Conditions: Relapsed Hodgkin Lymphoma|Refractory Hodgkin Lymphoma|Relapsed Non-Hodgkin Lymphoma|Refractory Non-Hodgkin Lymphoma|B-cell Lymphoma
Interventions: DRUG: ATRA|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bevacizumab and ICIs + hSRT in Symptomatic Melanoma Brain Metastases
Status: NOT_YET_RECRUITING
Conditions: Melanoma Brain Metastases
Interventions: DRUG: Bevacizumab|DRUG: Ipilimumab|DRUG: Nivolumab|RADIATION: Hypofractionated stereotactic radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Citrate Dialysis on Vascular Calcification
Status: ACTIVE_NOT_RECRUITING
Conditions: Vascular Calcification
Interventions: DEVICE: Citrate Dialysate|DEVICE: Standard Dialysate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Doppler Ultrasound Renal Arterial Resistive Indices As Predictor Of Multiorgan Failure In Patients With Acute Hypoxic Respiratory Failure Admitted To Respiratory Intensive Care Unit (Cryptic Shock Index- RICU)
Status: NOT_YET_RECRUITING
Conditions: Respiratory Failure|Multi Organ Failure
Interventions: OTHER: Doppler ultrasound assessment of renal arteria resistive index
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Neoadjuvant PD-1 in Newly Diagnosed Glioblastoma
Status: UNKNOWN
Conditions: Glioblastoma
Interventions: DRUG: Camrelizumab|RADIATION: radiation|DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Cilofexor in Adults With Primary Sclerosing Cholangitis
Status: TERMINATED
Conditions: Primary Sclerosing Cholangitis
Interventions: DRUG: Cilofexor|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Nausea and Pain Prophylaxis During Thyroid Surgery
Status: COMPLETED
Conditions: Thyroid Diseases|Parathyroid Diseases
Interventions: DRUG: dexamethasone|DRUG: natriumchloride 0,9%|DRUG: dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: HLA-A*0201 Restricted Peptide Vaccine Therapy With Gemcitabine With Gemcitabine in Patient Pancreatic Cancer (Phase1)
Status: UNKNOWN
Conditions: Pancreatic Cancer
Interventions: BIOLOGICAL: VEGFR1, VEGFR2|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prehabilitation in Elective Colorectal Resection: A Pilot Study (Prehab)
Status: UNKNOWN
Conditions: Colorectal Cancer
Interventions: OTHER: Physiatry Assessment|OTHER: Routine Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study Utilizing Rilonacept in Gout Exacerbations
Status: COMPLETED
Conditions: Acute Gout Flare
Interventions: DRUG: Rilonacept|DRUG: Indomethacin|OTHER: Placebo (for Indomethacin)|OTHER: Placebo (for Rilonacept)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Radiation Therapy in Treating Patients With Brain Cancer
Status: COMPLETED
Conditions: Brain and Central Nervous System Tumors
Interventions: DRUG: carmustine|DRUG: chemotherapy|DRUG: mitolactol|RADIATION: low-LET cobalt-60 gamma ray therapy|RADIATION: low-LET photon therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: A Study of Cell Therapy in COVID-19 Subjects With Acute Kidney Injury Who Are Receiving Renal Replacement Therapy
Status: UNKNOWN
Conditions: COVID-19|Acute Kidney Injury|Sepsis
Interventions: BIOLOGICAL: SBI-101
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Biphasic Insulin Aspart 30 Individually Adjusted by the Subject and the Trial Physician, Both Combined With Metformin in Subjects With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: biphasic insulin aspart 30
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety & Efficacy of DCR-PHXC in Patients With PH1/2 and ESRD
Status: RECRUITING
Conditions: Primary Hyperoxaluria Type 1|Primary Hyperoxaluria Type 2|End Stage Renal Disease
Interventions: DRUG: DCR-PHXC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: S0816 Fludeoxyglucose F 18-PET/CT Imaging and Combination Chemotherapy With or Without Additional Chemotherapy and G-CSF in Treating Patients With Stage III or Stage IV Hodgkin Lymphoma
Status: COMPLETED
Conditions: Lymphoma|Nonneoplastic Condition
Interventions: BIOLOGICAL: bleomycin sulfate|BIOLOGICAL: filgrastim|DRUG: ABVD regimen|DRUG: BEACOPP regimen|DRUG: cyclophosphamide|DRUG: dacarbazine|DRUG: doxorubicin hydrochloride|DRUG: etoposide|DRUG: prednisone|DRUG: procarbazine hydrochloride|DRUG: vinblastine sulfate|DRUG: vincristine sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Safety of Triple Therapy of Telmisartan/Amlodipine/Rosuvastatin
Status: UNKNOWN
Conditions: Hypertension|Dyslipidemias
Interventions: DRUG: NEWSTATIN TS|DRUG: CADUET
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Acupuncture on Pregnancy Rates in Women Undergoing in Vitro Fertilization With Preimplantation Genetic Screening
Status: UNKNOWN
Conditions: Infertility|Aneuploidy
Interventions: PROCEDURE: Laser and Traditional Acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trastuzumab and RAD001 in Patients With Human Epidermal Growth Receptor 2 (HER-2) Overexpressing Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer|Neoplasm Metastasis
Interventions: DRUG: Trastuzumab|DRUG: RAD001
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Intravenous Ibuprofen and Paracetamol in Patients With Sciatica Presented to the Emergency Department
Status: UNKNOWN
Conditions: Sciatica
Interventions: DRUG: paracetamol|DRUG: Ibuprofen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Human Non-Shivering Thermogenesis and Basal Metabolic Rate
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Propranolol|DRUG: Pindolol|DRUG: Dantrolene|DRUG: Magnesium Sulfate|DRUG: Caffeine|DRUG: Qysmia|DRUG: Topiramate|BEHAVIORAL: Phentermine|DRUG: Naltrexone|DRUG: Mirabegron 50mg|DRUG: Mirabegron 200mg|DRUG: Placebo Cohort 1|DRUG: Placebo Cohort 2|DRUG: Placebo for Mirabegron
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Focused Ultrasound and Gemcitabine in Breast Cancer
Status: RECRUITING
Conditions: Breast Cancer|Breast Neoplasms
Interventions: DRUG: Gemcitabine|DEVICE: Focused Ultrasound|OTHER: Gemcitabine and Focused Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hormone Therapy With or Without Squalamine Lactate in Treating Patients Who Are Undergoing a Radical Prostatectomy for Locally Advanced Prostate Cancer
Status: WITHDRAWN
Conditions: Prostate Cancer
Interventions: DRUG: bicalutamide|DRUG: leuprolide acetate|DRUG: squalamine lactate|PROCEDURE: adjuvant therapy|PROCEDURE: antiandrogen therapy|PROCEDURE: antiangiogenesis therapy|PROCEDURE: conventional surgery|PROCEDURE: neoadjuvant therapy|PROCEDURE: releasing hormone agonist therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endoscopic Papillary Large Balloon Dilatation Versus Mechanical Lithotripsy for Large Stones
Status: COMPLETED
Conditions: Common Bile Duct Stones
Interventions: PROCEDURE: Large balloon dilatation|PROCEDURE: Mechanical lithotripsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Mindfulness Based Cognitive Therapy (MBCT) Resiliency Program for Critical Care Nurses
Status: COMPLETED
Conditions: Burn-Out Syndrome|Work-Related Stress Disorder
Interventions: BEHAVIORAL: Mindfulness-Based Cognitive Therapy|BEHAVIORAL: Book Club Active Control Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial With Azacitidine in Newly Diagnosed Acute Myelogenous Leukemia (AML) Veterans Administration (VA) Elderly Patients Not Eligible for Standard Induction Therapy
Status: UNKNOWN
Conditions: Acute Myeloid Leukemia|Elderly
Interventions: DRUG: Azacitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Role of Immune System in Obesity-related Inflammation and Cardiometabolic Risk
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-alcoholic Fatty Liver Disease|Metabolic Syndrome|Metabolically Abnormal Obesity|Metabolically Normal Obesity|Obesity
Interventions: OTHER: Weight loss
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Bioavailability Study of Propranolol Under Fasting Conditions
Status: COMPLETED
Conditions: To Determine Bioequivalence Under Fasting Conditions
Interventions: DRUG: Propranolol|DRUG: Inderal-LA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: A Mindfulness-Based Cognitive Therapy for Suicidal Patients
Status: COMPLETED
Conditions: Suicidal Ideation|Suicide Attempt
Interventions: BEHAVIORAL: Mindfulness-Based Cognitive Therapy for Suicidal individuals (MBCT-S)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ATIBAR - Efficacy and Safety of Two Doses of AllerT in Patients Allergic to Birch Pollen
Status: COMPLETED
Conditions: Allergic Rhinitis
Interventions: DRUG: AllerT|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Does Glidescope Video Laryngoscope is Related to Less Hemodynamic Response?
Status: COMPLETED
Conditions: Blood Pressure
Interventions: DEVICE: Glidescope|DEVICE: Macintosh Laryngoscope
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: ExtraVascular Implantable Cardiac Defibrillator Continued Access Study
Status: WITHDRAWN
Conditions: Tachycardia|Ventricular Arrythmia
Interventions: DEVICE: Defibrillation using the Extravascular ICD
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Aim 2 - Conversations Can Save Lives: TALKing About Buprenorphine & Methadone for Opioid Use Treatment Initiation
Status: RECRUITING
Conditions: Opioid Use Disorder
Interventions: BEHAVIORAL: Talk About It (conversation aid)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Randomized Controlled Trial for Patients Underwent Total Hip Arthroplasties Assisted by Surgical Navigation System
Status: UNKNOWN
Conditions: Hip Arthropathy
Interventions: DEVICE: "VTS" surgical navigation system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Duration of Antibiotics for the Treatment of Gram-negative Bacilli Bacteremia
Status: COMPLETED
Conditions: Gram Negative Bacteremia
Interventions: DRUG: short-course antibiotic treatment|DRUG: accepted prolonged antibiotic treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics of Anidulafungin (Ecalta ®) Intravenous Given to Patients at High Risk for Developing Invasive Fungal Disease
Status: COMPLETED
Conditions: Leukemia|Myelodysplastic Syndrome|Leukemia, Myeloid, Acute
Interventions: DRUG: anidulafungin 200 mg q48h|DRUG: anidulafungin 300 mg q72h
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Efficacy of Preoperative Pectoral Nerve Block for Intraoperative Opioid Sparing Effect and Postoperative Analgesia
Status: COMPLETED
Conditions: Breast Cancer
Interventions: PROCEDURE: Pecs II block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Evaluation of Omegaven™ Parenteral Nutrition in Patients With Total Parenteral Nutrition (TPN)-Induced Cholestasis
Status: COMPLETED
Conditions: Parenteral Nutrition Associated Liver Disease PNALD|Cholestasis
Interventions: DRUG: Omegaven™
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open-label Study of Inhaled RVT-1601 in Preterm Infants
Status: COMPLETED
Conditions: Respiratory Morbidities of Prematurity (RMP)
Interventions: DRUG: RVT-1601
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: OPTI-FREE® PureMoist® for Presbyopic Contact Lens Wearers
Status: COMPLETED
Conditions: Presbyopia
Interventions: DEVICE: Opti-Free® PureMoist® contact lens solution|DEVICE: Habitual Multi-Purpose Contact Lens Solution|DEVICE: Habitual Contact Lenses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study To Compare the Effects of Insulin Peglispro and Glargine on Insulin Sensitivity and Meal Time Insulin Requirements in Type 2 Diabetics
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Insulin Peglispro|DRUG: Insulin Glargine|DRUG: Insulin Lispro
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Comparison of Silicone Hydrogel Contact Lenses: AIR OPTIX® COLORS Versus AIR OPTIX® AQUA
Status: COMPLETED
Conditions: Myopia
Interventions: DEVICE: Lotrafilcon B contact lens with color|DEVICE: Lotrafilcon B contact lens
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Use of Consent Language and Mode to Improve Interactive Voice Response Survey in Colombia and Uganda
Status: COMPLETED
Conditions: Surveys and Questionnaires|Noncommunicable Diseases
Interventions: OTHER: Modified Introduction|OTHER: Active Opt-in|OTHER: Active Opt-out|OTHER: Passive Opt-in
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Safety and Efficacy of Bimatoprost Solution in Increasing Overall Eyelash Prominence
Status: COMPLETED
Conditions: Eyelashes
Interventions: DRUG: Bimatoprost 0.03% sterile solution|DRUG: vehicle sterile solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study at the Man of the Profile of Chimiokines in the Anorexia Bound to the Cancerous Cachexy
Status: COMPLETED
Conditions: Cancer of the Pancreas|Anorexia
Interventions: OTHER: Dosage of chimiokines
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comorbidities Resolution After MGB Surgery and Change in Body Composition
Status: RECRUITING
Conditions: Morbid Obesity|Type2diabetes|Sleep Apnea|Hypothyroidism|Hypertension|Lipid Disorder|Non-Alcoholic Fatty Liver Disease|Chronic Venous Hypertension With Ulcer
Interventions: PROCEDURE: Mini gastric bypass surgery
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Heartrate and Breathing Effects on Attention and Memory 1
Status: COMPLETED
Conditions: Aging|Alzheimer Disease|Age-related Cognitive Decline
Interventions: BEHAVIORAL: Brain training|BEHAVIORAL: Paced breathing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE