pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Effectiveness of PRP, Conditioned Medium UC-MSCs Secretome and Hyaluronic Acid for the Treatment of Knee Osteoarthritis
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: BIOLOGICAL: Platelet-rich Plasma|BIOLOGICAL: Conditioned Medium From Umbilical Cord Mesenchymal Stem Cell Culture (MSCs) Secretome|DRUG: Low Molecular Weight Hyaluronic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Etiologies, Investigations and Outcomes of Patients Presenting With Hemoptysis
Status: UNKNOWN
Conditions: Hemoptysis|Haemoptysis|Lung Disease|Pneumonia|Tuberculosis|Bronchiectasis|Respiratory Tract Infections|Respiratory Tract Diseases|Bronchitis|Mycobacterium Infections|Bronchial Disease|Pulmonary Hemorrhage|Signs and Symptoms|Signs and Symptoms, Respiratory|Pathologic Processes|Mycosis|Hemorrhage|Lung Cancer|Pulmonary Embolism|Arteriovenous Fistula
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Skin Balancing Gel Cream Safety and Influence of Skin Microbiome on Acne Prone Skin
Status: RECRUITING
Conditions: Skin Microboime|Acne
Interventions: OTHER: Balancing gel cream
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Influence of Adalimumab on Cardiovascular and Metabolic Risk in Psoriasis
Status: UNKNOWN
Conditions: Psoriasis|Cardiovascular Diseases|Diabetes Mellitus, Type 2
Interventions: DRUG: Adalimumab treatment arm|DRUG: Fumaric acid esters treatment group|OTHER: Narrow band UVB radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study To Evaluate The Efficacy And Safety Of Balovaptan In Adults With Post-Traumatic Stress Disorder (PTSD)
Status: COMPLETED
Conditions: Stress Disorders, Post-Traumatic
Interventions: DRUG: Balovaptan|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Therapy With Verapamil or Carvedilol in Chronic Heart Failure
Status: UNKNOWN
Conditions: Dilated Cardiomyopathy
Interventions: DRUG: Verapamil|DRUG: Carvedilol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Ultrasonic Versus Ultrasonic+ for Effective Sanative Therapy
Status: COMPLETED
Conditions: Periodontitis|Periodontal Pocket
Interventions: DEVICE: Ultrasonic alone|DEVICE: Ultrasonic+
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Effect of Decision Support System on Symptom Self-Management in Non-Hodgkin Lymphoma Patients
Status: NOT_YET_RECRUITING
Conditions: Decision Support System|Non-Hodgkin Lymphoma
Interventions: BEHAVIORAL: The effectiveness of the online decision support system developed for symptom self-management|BEHAVIORAL: Symptom self-management with an education booklet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Open Label Extension Study Evaluating Safety and Biological Activity of C2L-OCT-01 PR in Acromegalic Patients
Status: COMPLETED
Conditions: Acromegaly
Interventions: DRUG: C2L-OCT-01 PR 30 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Monocenter 6-period Study in Patients With Seasonal Allergic Rhinitis to Birch Pollen to Establish a Challenge Model With Natural Birch Pollen in an Environmental Challenge Chamber (ECC)
Status: COMPLETED
Conditions: Seasonal Allergic Rhinitis
Interventions: OTHER: Exposure to birch pollen
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of CM310 Injection in Adolescent Subjects With Atopic Dermatis
Status: NOT_YET_RECRUITING
Conditions: Atopic Dermatitis
Interventions: BIOLOGICAL: CM310|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Exercise Training at Different Timeline on Shoulder Dysfunction After Breast Cancer Modified Radical Mastectomy
Status: COMPLETED
Conditions: Shoulder Dysfunction|Breast Cancer|Modified Radical Mastectomy
Interventions: OTHER: 7 days SIE plus 4 weeks PRE|OTHER: 7 days SIE plus 3 weeks PRE|OTHER: 3 days SIE plus 4 weeks PRE|OTHER: 3 days SIE plus 3 weeks PRE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Effectiveness of a Multifocal Intraocular Lens (IOL)
Status: COMPLETED
Conditions: Cataract
Interventions: DEVICE: Tecnis ZM900 Multifocal Intraocular Lens|DEVICE: CeeOn 911A monofocal IOL
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Articaine Efficacy and Safety for Children Below Age of 4-years
Status: COMPLETED
Conditions: Behaviour Assessment|Pain
Interventions: DRUG: Articaine 4%/Epi 1:100000 Inj Cart 1.7Ml|DRUG: lidocaine hydrochloride 2% and epinephrine 1:100000
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Stereotactic Body Radiation Therapy and Transarterial Chemoembolization in Treating Patients With Liver Cancer That Cannot Be Removed by Surgery
Status: COMPLETED
Conditions: Child-Pugh Class A|Child-Pugh Class B|Stage IIIA Hepatocellular Carcinoma|Stage IIIB Hepatocellular Carcinoma|Stage IIIC Hepatocellular Carcinoma|Stage IVA Hepatocellular Carcinoma|Stage IVB Hepatocellular Carcinoma
Interventions: OTHER: Laboratory Biomarker Analysis|RADIATION: Stereotactic Body Radiation Therapy|PROCEDURE: Transarterial Chemoembolization
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Study of the Use of a Mesh to Prevent Parastomal Hernia After Laparoscopic Abdominoperineal Resection
Status: COMPLETED
Conditions: Parastomal Hernia
Interventions: PROCEDURE: laparoscopic abdominoperineal resection with a lightweight mesh (polypropylene and poliglecaprone 25)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Improving Muslim Women's Uptake of Cancer Screening (IMCAN)
Status: RECRUITING
Conditions: Breast Cancer|Bowel Cancer|Cervical Cancer
Interventions: OTHER: In-person peer-led faith-based intervention to encourage breast, bowel, and cervical screening uptake among Muslim women|OTHER: Online In-person peer-led faith-based intervention to encourage breast, bowel, and cervical screening uptake among Muslim women
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effects of Brain Stimulation During Daytime Nap on Memory Consolidation in Younger, Healthy Subjects
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DEVICE: brain stimulation|DEVICE: no stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Combined Letrozole and Clomid in Women With Infertility and PCOS
Status: COMPLETED
Conditions: Polycystic Ovary Syndrome|Infertility
Interventions: DRUG: Clomiphene|DRUG: Letrozole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Anti Aging on Fitness Enhancement in Premenopausal Women
Status: NOT_YET_RECRUITING
Conditions: Menopause Early
Interventions: OTHER: aerobic exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of MR Enteroclysis and MRI With Per Oral Contrast Using a 6 % Mannitol Solution.
Status: UNKNOWN
Conditions: Magnetic Resonance Imaging, Intestine Small, Crohn Disease.
Interventions: PROCEDURE: MRI of the small bowel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Influence of Resection Margin on the Recurrence of Early-stage Hepatocellular Carcinoma
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma
Interventions: PROCEDURE: Wide resection margin >1cm|PROCEDURE: Narrow resection margin <1cm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Intracoronary Infusion of Different Medicine in STEMI Patients Undergoing Primary PCI
Status: UNKNOWN
Conditions: ST Segment Elevation Myocardial Infarction
Interventions: DRUG: Alprostadil|DRUG: Nicorandil|DRUG: Nitroglycerin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Oshadi D & Oshadi R Combined With Salvage Chemotherapy for Relapsed Acute Myeloid Leukemia or Lymphoid Leukemia Patients
Status: SUSPENDED
Conditions: Acute Myeloid Leukemia|Lymphoid Leukemia
Interventions: DRUG: Oshadi D & Oshadi R;|DRUG: salvage therapy cytosar and mitoxantrone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Durvalumab (MEDI4736) and Tremelimumab in Hormone Receptor-positive, Hypermutated Metastatic Breast Cancer Identified by Whole Exome Sequencing
Status: COMPLETED
Conditions: Metastatic Breast Cancer
Interventions: DRUG: Durvalumab with Tremelimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Differential Air Pressure Technology for Treatment of Diabetic Elderly Patients
Status: COMPLETED
Conditions: Diabetic Polyneuropathy
Interventions: OTHER: Antigravity treadmill training 100% weight bearing|OTHER: Antigravity treadmill training 75% weight bearing|OTHER: Antigravity treadmill training 50% weight bearing|OTHER: Antigravity treadmill training 25% weight bearing|OTHER: The conventional exercise program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hormonal Mechanisms of Sleep Restriction
Status: COMPLETED
Conditions: Insulin Resistance
Interventions: DRUG: Ketoconazole|DRUG: Hydrocortisone|DRUG: Testosterone|DRUG: Placebo for ketoconazole|DRUG: Placebo for hydrocortisone|DRUG: Placebo for testosterone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Motivational Interviewing in Hearing Aid Users
Status: ENROLLING_BY_INVITATION
Conditions: Hearing Loss|Motivation|Hearing Disability|Hearing Disorders and Deafness
Interventions: BEHAVIORAL: Motivational interviewing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: BUSCLAB - Buscopan to Prevent Slow Progress in Labor
Status: COMPLETED
Conditions: Labor (Obstetrics)--Complications|Labor; Prolonged, First Stage
Interventions: DRUG: Butylscopolamine Bromide 20 MG/ML|DRUG: Sodium Chloride 9mg/mL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Sequential Multiple Assessment Randomized Trial of Exercise for PAD: SMART Exercise for PAD (SMART PAD)
Status: RECRUITING
Conditions: Peripheral Arterial Disease|Aging|Peripheral Vascular Diseases|Walking, Difficulty
Interventions: BEHAVIORAL: Supervised Treadmill Exercise|BEHAVIORAL: Home-Based Exercise|DIETARY_SUPPLEMENT: Nitrate-rich beetroot Juice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Action Observation Therapy With Otago Exercises on Balance and Quality of Life in Older Adults
Status: RECRUITING
Conditions: Balance; Distorted
Interventions: OTHER: Action Observation Therapy and Otago Exercises|OTHER: Otago Exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Isotretinoin in Treating Young Patients With High-Risk Neuroblastoma
Status: UNKNOWN
Conditions: Neuroblastoma
Interventions: DRUG: isotretinoin|GENETIC: DNA analysis|GENETIC: polymerase chain reaction|OTHER: laboratory biomarker analysis|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Virtual Reality-Assisted Cognitive Behavioral Therapy for Alcohol Dependence (CRAVR-Pilot)
Status: UNKNOWN
Conditions: Alcohol Dependence, in Remission|Addiction, Alcohol
Interventions: BEHAVIORAL: Virtual Reality Cognitive Behavioral Therapy (CRAVR)|BEHAVIORAL: CBT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Shock Wave and Core Exercises for Postpartum Sacroiliac Pain
Status: NOT_YET_RECRUITING
Conditions: Postpartum Sacroiliac Joint Pain
Interventions: OTHER: Shock wave therapy and core stability exercises|OTHER: core stability exercises only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Adenosine to Assess Complete Conduction Block During Catheter Ablation of Paroxysmal Atrial Fibrillation
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DRUG: Adenosine|DRUG: Isoproterenol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transversal, Controlled and Not Randomized Study, Laying on the Desire of Children and Eating Disorders in a Population of Infertile Women
Status: TERMINATED
Conditions: Infertility|Eating Disorders
Interventions: OTHER: Autoquestionnary|OTHER: semi-structured interview
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Clinical Study of Cord Blood-Derived CAR-NK Cells in Gastric Cancer and Pancreatic Cancer
Status: RECRUITING
Conditions: Gastric Cancer|Pancreas Adenocarcinoma
Interventions: BIOLOGICAL: CB CAR-NK182
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Contralateral Strength-training After Anterior Cruciate Ligament (ACL) Reconstruction
Status: COMPLETED
Conditions: Muscle Weakness After Anterior Cruciate Ligament Reconstruction
Interventions: BEHAVIORAL: Neuromuscular electrical stimulation|BEHAVIORAL: eccentric training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Different Doses of a Novel Treatment for Onychomycosis
Status: COMPLETED
Conditions: Distal, Subungual Onychomycosis
Interventions: DRUG: AN2690, 2.5%|DRUG: AN2690, 5%|DRUG: AN2690, 7.5%|DRUG: AN2690 Solution Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cerebral Vascular Effects of Dexmedetomidine Versus Propofol Sedation in Intubated Mechanically Ventilated ICU Patients
Status: SUSPENDED
Conditions: Sedation
Interventions: DRUG: 0.2-0.7 mcg/kg/h dexmedetomedine infusion.|DRUG: 10-70 mcg/kg/h propofol infusion.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of a High Dosage Compared to the Label Dosage of Somatropin in Early Pubertal Stage Children With Growth Hormone Deficiency
Status: COMPLETED
Conditions: Growth Hormone Deficiency
Interventions: DRUG: Somatropin|DRUG: Somatropin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HIP Fracture Oral thromboPROphylaxis (Hip PRO Pilot)
Status: NOT_YET_RECRUITING
Conditions: Hip Fractures
Interventions: DRUG: Rivaroxaban 10mg|DRUG: acetylsalicylic acid (ASA) 81mg Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Functional Imaging of Baby Brains
Status: NOT_YET_RECRUITING
Conditions: Hypoxia Ischemia, Cerebral|Hypoxia-Ischemia, Brain|Hypoxia Neonatal|Hypoxic-Ischemic Encephalopathy
Interventions: DEVICE: Diffuse Optical Tomography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: FOLFOX-HAIC Plus Lenvatinib and Toripalimab vs. FOLFOX-HAIC Plus Lenvatinib for Advanced Hepatocellular Carcinoma: a Randomized Controlled and Double-blind Trial
Status: RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: PROCEDURE: Hepatic arterial infusion chemotherapy|DRUG: Lenvatinib|DRUG: Toripalimab|DRUG: oxaliplatin , fluorouracil, and leucovorin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinic-based Intervention to Promote Cervical Cancer Prevention Behaviors
Status: COMPLETED
Conditions: Cervical Cancer
Interventions: BEHAVIORAL: Step Up to Prevention|BEHAVIORAL: Step Up to Prevention: knowledge|BEHAVIORAL: Step Up to Prevention:belief|BEHAVIORAL: Offered HPV vaccine only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Single Ascending Dose Study of MEDI1341 in Healthy Volunteers
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DRUG: MEDI1341|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mechanisms of Lipodystrophy in HIV-Infected Pateints
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Nelfinavir|DRUG: Efavirenz
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Magnesium Sulfate Infusion Rate on Magnesium Retention in Critically Ill Patients
Status: TERMINATED
Conditions: Primary Hypomagnesemia (Disorder)
Interventions: DRUG: Magnesium Sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility and Therapeutic Potential of Free Fat Grafts in the Treatment of Urethral Strictures
Status: UNKNOWN
Conditions: Urethral Stricture|Fat Graft
Interventions: PROCEDURE: Direct visual urethrotomy|PROCEDURE: Autologous fat grafting
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prolactin Receptor and Breast Diseases
Status: COMPLETED
Conditions: Benign Breast Disease|Breast Cancer
Interventions: BIOLOGICAL: blood collection for hormonal status analysis|PROCEDURE: breast Biopsy or surgery|GENETIC: blood collection|OTHER: ultrasonography (pelvis and breast), bone mineral density
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Stereotactic Body Radiation Therapy in Treating Patients With High-Risk Prostate Cancer Undergoing Surgery
Status: COMPLETED
Conditions: Stage I Prostate Adenocarcinoma American Joint Committee on Cancer (AJCC) v7|Stage II Prostate Adenocarcinoma AJCC v7|Stage III Prostate Adenocarcinoma AJCC v7
Interventions: OTHER: Laboratory Biomarker Analysis|OTHER: Quality-of-Life Assessment|RADIATION: Stereotactic Body Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Evaluate the Comparative Pharmacokinetics of Orally Administered EQ143 in Different Racial and Ethnic Populations
Status: COMPLETED
Conditions: NSCLC|Healthy Volunteers|Pharmacokinetics
Interventions: DRUG: aumolertinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Biomarkers in Patients With Solid Tumors (0000-097)(COMPLETED)
Status: COMPLETED
Conditions: Tumors
Interventions: OTHER: Biomarker sample collection before and after dosing with cytotoxic agent(s)|OTHER: Biomarker sample collection before and after dosing with cytotoxic agent(s)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Assess the Feasibility of Romidepsin Combined With Brentuximab Vedotin in Cutaneous T-cell Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Cutaneous T-cell Lymphoma (CTCL)
Interventions: DRUG: Romidepsin|DRUG: Brentuximab vedotin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Diagnosis of Mortality Using Admission CT Perfusion in Severe Traumatic Brain Injury Patients (ACT-TBI Study)
Status: COMPLETED
Conditions: Traumatic Brain Injury
Interventions: DIAGNOSTIC_TEST: CT Perfusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Phase II Study of Teriflunomide as Adjunctive Therapy to Glatiramer Acetate in Subjects With Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DRUG: Teriflunomide|DRUG: Placebo (for teriflunomide)|DRUG: Glatiramer Acetate (GA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial for a Outpatient Clinical Management for Complicated Acute Appendicitis
Status: NOT_YET_RECRUITING
Conditions: Acute Appendicitis|Appendicitis Perforated|Appendicitis Suppurative
Interventions: BEHAVIORAL: Hospitalization|BEHAVIORAL: Outpatient
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Autologous Stem Cell Therapy for Fracture Non-union Healing
Status: COMPLETED
Conditions: Non-union of Fractures
Interventions: BIOLOGICAL: carrier plus in vitro expanded autologous BMSCs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Tranexamic Acid in Reducing Myomectomy Associated Blood Loss in Federal Teaching Hospital Abakaliki.
Status: COMPLETED
Conditions: To Determine Efficacy of Tranexamic Acid in Reducing Blood Loss During Myomectomy
Interventions: DRUG: Tranexamic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Anti-Inflammatory Treatment of Uremic Cardiomyopathy With Colchicine
Status: RECRUITING
Conditions: Chronic Kidney Diseases
Interventions: DRUG: Colchicine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigating Magnesium Glycinate in Structure/Function Role of Hot Flashes.
Status: COMPLETED
Conditions: Hot Flashes
Interventions: DIETARY_SUPPLEMENT: 400mg Magnesium Glycinate BID|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Hemoperfusion With Polymyxin B in Septic Shock Associated With Severe Endotoxemia in Cardiac Surgery Patients (РМХ vs SS)
Status: RECRUITING
Conditions: Multiple Organ Dysfunction With Severe Endotoxemia
Interventions: DEVICE: hemoperfusion with polymyxin B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: LMP1 CAR-T for Patients With LMP1 Positive Infectious Diseases and Hematological Malignancies
Status: NOT_YET_RECRUITING
Conditions: Infectious Diseases|Hematological Malignancies
Interventions: DRUG: LMP1 CAR T-cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pioglitazone vs Placebo in Combination With Niacin Extended Release on Low HDL
Status: COMPLETED
Conditions: Metabolic Syndrome
Interventions: DRUG: Pioglitazone|OTHER: Placebo|DRUG: Niacin ER|DRUG: Aspirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: TLK286 in Combination With Doxil in Platinum Refractory or Resistant Ovarian Cancer
Status: COMPLETED
Conditions: Ovarian Neoplasms
Interventions: DRUG: TLK286
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Saliva-based Detection of CD44
Status: COMPLETED
Conditions: Oral Cavity Squamous Cell Carcinoma|Oropharynx Squamous Cell Carcinoma|Squamous Cell Carcinoma of the Oropharynx|Squamous Cell Carcinoma of the Head and Neck
Interventions: DEVICE: OncAlert
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Emergency Stroke Unit for Acute Cerebrovascular Events ( ESU-ACE-B )
Status: RECRUITING
Conditions: Ischemic Stroke, Acute
Interventions: COMBINATION_PRODUCT: Emergency Stroke Unit based on 0.23-T MRI|COMBINATION_PRODUCT: Standard stroke unit adherent to guidelines
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study to Evaluate the Efficacy of a Stannous Fluoride Dentifrice in the Relief of Dentinal Hypersensitivity in a Chinese Population
Status: COMPLETED
Conditions: Dentin Sensitivity
Interventions: OTHER: Sensodyne Sensitivity & Gum|OTHER: Crest Cavity Protection Fresh Lime|OTHER: Sensodyne Repair and Protect
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Resilience Training for Work-related Stress in Employees and the Influence of the Lecture Format on Training Success
Status: COMPLETED
Conditions: Work-Related Stress|Burnout
Interventions: OTHER: Resilience training with mobile HRV-BfB based on an e-learning approach (with digital lectures)|OTHER: Resilience training with mobile HRV-BfB based on a blended learning approach (with live lectures)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Multicenter Phase II Study of Transanal TME (taTME)
Status: ACTIVE_NOT_RECRUITING
Conditions: Rectal Cancer|Surgery
Interventions: PROCEDURE: Transanal Total Mesorectal Excision (taTME)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized Trial to Reduce the Disparity in Live Donor Kidney Transplantation
Status: COMPLETED
Conditions: Chronic Kidney Disease|End-stage Renal Disease
Interventions: BEHAVIORAL: Group-Based (GB) Intervention|BEHAVIORAL: Home-Based (HB) Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Bioequivalence Study of Lamotrigine Dispersible/Chewable Tablets 100mg Compared With Compressed Tablet 100 mg
Status: COMPLETED
Conditions: Epilepsy
Interventions: DRUG: Lamotrigine Dispersible/Chewable tablet|DRUG: Lamotrigine Compressed tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Avastin, Fluorouracil, Doxorubicin and Streptozocin in Locally Advanced and Metastatic Pancreatic Endocrine Tumors
Status: TERMINATED
Conditions: Pancreatic Cancer
Interventions: DRUG: Avastin|DRUG: Fluorouracil|DRUG: Doxorubicin|DRUG: Streptozocin|DRUG: Dexamethasone|DRUG: Ondansetron
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Characterization and Detection of Prolonged Endothelin Receptors Antagonists Administration
Status: COMPLETED
Conditions: Pulmonary Hypertension
Interventions: DRUG: Bosentan|DRUG: Ambrisentan|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Investigation of the Effects of Exercise and Kinesiological Taping on Spinal Deformities and Serum Markers in Individuals With Scoliosis
Status: NOT_YET_RECRUITING
Conditions: Scoliosis|Scoliosis Idiopathic|Musculoskeletal Deformity
Interventions: OTHER: Just Exercise|OTHER: Exercise|OTHER: Taping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Obstructive Jaundice in Autoimmune Pancreatitis and/or Immunoglobulin G4-related Sclerosing Cholangitis by Corticosteroids
Status: UNKNOWN
Conditions: Autoimmune Pancreatitis|IgG4-related Sclerosing Cholangitis|Obstructive Jaundice
Interventions: DRUG: corticosteroids|PROCEDURE: biliary stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Arthroscopic Rotator Cuff Repair With Platelet-Rich Plasma (PRP) in Medium to Large Rotator Cuff Tears
Status: COMPLETED
Conditions: Rotator Cuff Tear
Interventions: PROCEDURE: Conventional arthroscopic rotator cuff repair|PROCEDURE: Arthroscopic rotator cuff repair with PRP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Driving Simulator Performance After Intake of Zopiclone Sleeping Pills
Status: WITHDRAWN
Conditions: Automobile Driving
Interventions: DRUG: Zopiclone|DRUG: Ethanol|DRUG: Placebo pill|DRUG: Placebo drink
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Evaluation of New Fitting Characteristics for Extended Wear Hearing Aid Technology
Status: COMPLETED
Conditions: Hearing Loss
Interventions: DEVICE: Lyric Hearing Aid- Experimental Design|DEVICE: Lyric Hearing Aid- Commercially Available
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Two Different High Power Ablative Lasers in the Treatment of Oral Leukoplakia
Status: COMPLETED
Conditions: Leukoplakic Lesions
Interventions: PROCEDURE: Er:YAG laser|PROCEDURE: Er,Cr:YSGG laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral Rehydration Therapy in Burn Patients
Status: TERMINATED
Conditions: Burn Any Degree Involving 20-29 Percent of Body Surface|Burn Any Degree Involving 30-39 Percent of Body Surface|Burn Any Degree Involving 40-49 Percent of Body Surface|Burn Any Degree Involving 50-59 Percent of Body Surface|Burn Any Degree Involving 60-65 Percent of Body Surface|Fluid Resuscitation
Interventions: DRUG: CeraLyte 90
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Structured Education to Decrease Blood Pressure for Hypertension in Elderly
Status: UNKNOWN
Conditions: Hypertension
Interventions: OTHER: Structured education|OTHER: Checklist|OTHER: Without structure education with checklist
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study in Japan of the Safety and Antiviral Activity With Chronic Hepatitis B Infection
Status: COMPLETED
Conditions: Chronic Hepatitis B
Interventions: DRUG: Entecavir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Does Ultrasound-guided Suprascapular Nerve Block Provide Additional Benefit Over Traditional Rehabilitation Program for Patients With Chronic Shoulder Pain
Status: UNKNOWN
Conditions: Suprascapular Nerve Block
Interventions: DRUG: suprascapular nerve block|OTHER: physical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Inhaled GM-CSF for Respiratory Virus-Associated Severe Pneumonia
Status: WITHDRAWN
Conditions: Acute Respiratory Distress Syndrome|Pneumonia|Respiratory Virus Infection
Interventions: DRUG: Sargramostim 0.04 mcg/kg/dose|DRUG: Sargramostim 0.2mcg/kg/dose|DRUG: Sargramostim 1 mcg/kg/dose
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of Eptinezumab for the Prevention of Migraine in Participants That Are Not Helped by Previous Preventive Treatments
Status: COMPLETED
Conditions: Migraine
Interventions: DRUG: Eptinezumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Colchicine in Belgium in Patients With Coronary Artery Disease After Percutaneous Coronary Intervention
Status: RECRUITING
Conditions: Coronary Artery Disease
Interventions: DRUG: Colchicine 0.5 MG Oral Tablet|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: To Demonstrate the Relative Bioavailability of Atenolol Tablets
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Atenolol Tablets 100 mg (Cord Laboratories)|DRUG: Atenolol Tablets 100 mg (Stuart Pharmaceutical)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Is Desmoplastic Stromal Reaction Useful to Modulate Lymph Node Dissection in Sporadic Medullary Thyroid Carcinoma?
Status: COMPLETED
Conditions: Medullary Thyroid Cancer|Medullary Carcinoma|Medullary Tumor|Medullary Neoplasms|Desmoplasia|Desmoplastic|Desmoplastic Reaction|Lymph Node Metastasis|Lymph Node Disease
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Mechanism for the Effects of Joint Biomechanical Properties on Medial Cartilage of Tibiofemoral Joint Degeneration
Status: UNKNOWN
Conditions: Anterior Cruciate Ligament Injuries|Cartilage Degeneration
Interventions: DIAGNOSTIC_TEST: gait testing, functional MRI
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of DSP-7888 Dosing Emulsion in Adult Patients With Advanced Malignancies
Status: COMPLETED
Conditions: Acute Myeloid Leukemia|Myelodysplastic Syndromes|Glioblastoma Multiforme|Melanoma|Non-Small Cell Lung Cancer|Ovarian Cancer|Pancreatic Cancer|Sarcoma|Renal Cell Carcinoma
Interventions: DRUG: DSP-7888 Dosing Emulsion
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase III Study of AK112 for NSCLC Patients
Status: RECRUITING
Conditions: Non-Squamous Non-small Cell Lung Cancer
Interventions: DRUG: AK112 Injection|DRUG: Placebo Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Wearable Airbag Technology to Mitigate Falls in Individuals With High Fall Risk
Status: ACTIVE_NOT_RECRUITING
Conditions: Stroke|Parkinson Disease|Lower Limb Amputation Knee|Fall Injury|Fall Patients|Falling
Interventions: DEVICE: Airbag Belt Fall Protection System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Extracorporeal Shock Waves Therapy (ESWT) vs Exercise in Thumb Osteoarthritis
Status: RECRUITING
Conditions: Thumb Osteoarthritis|Hand Injuries
Interventions: DEVICE: "Minilith", Storz, Swiss
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Sacituzumab Govitecan Plus Pembrolizumab in Resectable Non-Small Cell Lung Cancer
Status: RECRUITING
Conditions: Lung Cancer
Interventions: DRUG: Sacituzumab Govitecan|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Liposomal Bupivacaine in Total Knee Arthroplasty
Status: COMPLETED
Conditions: Knee Osteoarthritis|Anesthesia, Local
Interventions: DRUG: Exparel|PROCEDURE: Adductor block protocol|PROCEDURE: peri-articular injection protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Early Jejunostomy Nutrition Minimizes Time to Chemotherapy
Status: UNKNOWN
Conditions: Gastric Cancer|Laparoscopic Surgery|Chemotherapy
Interventions: PROCEDURE: Jejunostomy|OTHER: Early oral nutrition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Rapastinel as Monotherapy in Major Depressive Disorder (MDD)
Status: WITHDRAWN
Conditions: Depressive Disorder, Major
Interventions: DRUG: Rapastinel|DRUG: Vortioxetine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Tazemetostat in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With EZH2, SMARCB1, or SMARCA4 Gene Mutations (A Pediatric MATCH Treatment Trial)
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Malignant Solid Neoplasm|Ann Arbor Stage III Hodgkin Lymphoma|Ann Arbor Stage III Non-Hodgkin Lymphoma|Ann Arbor Stage IV Hodgkin Lymphoma|Ann Arbor Stage IV Non-Hodgkin Lymphoma|Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor|Low Grade Glioma|Recurrent Ependymoma|Recurrent Ewing Sarcoma|Recurrent Glioma|Recurrent Hepatoblastoma|Recurrent Hodgkin Lymphoma|Recurrent Langerhans Cell Histiocytosis|Recurrent Malignant Germ Cell Tumor|Recurrent Malignant Glioma|Recurrent Malignant Solid Neoplasm|Recurrent Medulloblastoma|Recurrent Neuroblastoma|Recurrent Non-Hodgkin Lymphoma|Recurrent Osteosarcoma|Recurrent Peripheral Primitive Neuroectodermal Tumor|Recurrent Primary Central Nervous System Neoplasm|Recurrent Rhabdoid Tumor|Recurrent Rhabdomyosarcoma|Recurrent Soft Tissue Sarcoma|Refractory Hodgkin Lymphoma|Refractory Langerhans Cell Histiocytosis|Refractory Malignant Germ Cell Tumor|Refractory Malignant Glioma|Refractory Malignant Solid Neoplasm|Refractory Medulloblastoma|Refractory Neuroblastoma|Refractory Non-Hodgkin Lymphoma|Refractory Osteosarcoma|Refractory Peripheral Primitive Neuroectodermal Tumor|Refractory Rhabdoid Tumor|Refractory Soft Tissue Sarcoma|Rhabdoid Tumor|Stage III Soft Tissue Sarcoma AJCC v7|Stage IV Soft Tissue Sarcoma AJCC v7|Wilms Tumor
Interventions: DRUG: Tazemetostat
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of an Inactivated Pandemic Influenza Vaccine
Status: COMPLETED
Conditions: Pandemic Influenza|Prevention
Interventions: BIOLOGICAL: pandemic influenza vaccine (H5N1 strain NIBRG-14)|BIOLOGICAL: pandemic influenza vaccine (H5N1 strain NIBRG-14)|BIOLOGICAL: pandemic influenza vaccine (H5N1 strain NIBRG-14)|BIOLOGICAL: pandemic influenza vaccine (H5N1 strain NIBRG-14)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Dietary Potassium Liberalization in Pre-Dialysis Patients
Status: RECRUITING
Conditions: Chronic Kidney Disease|Hyperkalemia
Interventions: DIETARY_SUPPLEMENT: Liberalized dietary potassium via fruits and vegetables|DIETARY_SUPPLEMENT: Standard dietary potassium restriction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chardonnay Marc and Vascular Response
Status: RECRUITING
Conditions: Cardiovascular Diseases|Vascular Dilation|Oxidative Stress
Interventions: OTHER: Low Flavanol Cocoa Powder|OTHER: High Flavanol Cocoa Powder|OTHER: Vine to Bar Chocolate - 2 servings|OTHER: Vine to Bar Chocolate - 1 serving|OTHER: Vine to Bar Chocolate covered almonds
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Validation of the International Metastatic Renal Cell Carcinoma Database Consortium (IMDC) Prognostic Classification for Targeted Therapies (TKI/mTOR Inhibitors) in Second Line After First Line Treatment With Pazopanib
Status: COMPLETED
Conditions: Metastatic Renal Cell Carcinoma
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effectiveness of Adjunctive Hyaluronic Acid Application in Coronally Advanced Flap in Single Gingival Recession Sites
Status: COMPLETED
Conditions: Gingival Recession
Interventions: PROCEDURE: coronally advanced flap|DEVICE: hyaluronic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Sirolimus-Coated BX VELOCITY Balloon-Expandable Stent in Treatment of de Novo Native Coronary Artery Lesions (SIRIUS)
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DEVICE: CYPHER Sirolimus-Eluting Stent|DEVICE: Uncoated BX VELOCITY Balloon-Expandable Stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Decitabine Given to Adults With Advanced-Stage Myelodysplastic Syndromes
Status: COMPLETED
Conditions: Myelodysplastic Syndrome
Interventions: DRUG: Decitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Short Term Safety and Efficacy of Inhaled L-arginine in Patients With Cystic Fibrosis
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: L-arginine|DRUG: L-arginine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prasugrel Versus High Dose Clopidogrel in Clopidogrel Resistant Patients Undergoing Chronic Hemodialysis
Status: COMPLETED
Conditions: Hemodialysis|Chronic Renal Failure
Interventions: DRUG: Prasugrel|DRUG: Clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multiple Dose Ethnobridging PK Study in Healthy Subjects
Status: COMPLETED
Conditions: Inflammatory Bowel Diseases|IBD
Interventions: DRUG: TD-1473 - Dose A|DRUG: TD-1473 - Dose B|DRUG: TD-1473 - Dose C|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intrathecal Prilocaine and Adductor Canal Block vs Intrathecal Bupivacaine Alone for Ambulatory Knee Arthroscopy
Status: RECRUITING
Conditions: Post Operative Pain
Interventions: DRUG: spinal anesthesia with hyperbaric prilocaine+adductor canal block (ACB) with bupivacaine|DRUG: spinal anesthesia with bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Magnetic Seizure Therapy for Schizophrenia
Status: TERMINATED
Conditions: Schizophrenia
Interventions: DEVICE: Magpro X100 + Option|DEVICE: ThymatronSystem Ⅳ Electroconvulsive System|OTHER: treatment as usual (TAU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Closed-loop Control of Postprandial Glucose Levels in Adults With Type 1 Diabetes
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: OTHER: 15-hour intervention|DRUG: Insulin (Lispro, Aspart or guilisine)|DRUG: Glucagon (Eli Lilly)|OTHER: Closed-loop strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT