pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: AKI Cardiosurgery Diagnostic Study (AKI-CDS)
Status: UNKNOWN
Conditions: Acute Kidney Injury|Renal Replacement Therapy
Interventions: DIAGNOSTIC_TEST: Biomarker ("penKid", adrenomedulin, C-terminal alpha-1 antitrypsin peptide)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Exercise on Gut Microbiota in Type 2 Diabetic Patients
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus|Insulin Sensitivity/Resistance
Interventions: BEHAVIORAL: Combined aerobic and strength exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of RNActive®-Derived Prostate Cancer Vaccine in Metastatic Castrate-refractory Prostate Cancer
Status: TERMINATED
Conditions: Prostate Cancer
Interventions: BIOLOGICAL: CV9104|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Standard Treatment +/- Enoxaparin in Small Cell Lung Cancer
Status: COMPLETED
Conditions: Small Cell Lung Cancer
Interventions: DRUG: cisplatinum or carboplatin and e.g.etoposide.|DRUG: cisplatinum or carboplatin and e.g.etoposide+enoxaparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Pharmacokinetics of Piperacillin-tazobactam Extended Infusion in Infants and Children (PIP-TAZO)
Status: UNKNOWN
Conditions: Infection
Interventions: DRUG: Piperacillin-tazobactam
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GCPGC in Chemotherapy-induced Neutropenia
Status: COMPLETED
Conditions: Chemotherapy Induced Neutropenia
Interventions: BIOLOGICAL: GCPGC 3.6mg|BIOLOGICAL: GCPGC 6mg|BIOLOGICAL: Neulasta (pegfilgrastim) 6mg|BIOLOGICAL: GCPGC 6mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Screening for Mental Health Concerns for at-Risk Community Living Chinese Seniors
Status: UNKNOWN
Conditions: Major Depressive Disorder|Dementia
Interventions: BEHAVIORAL: Participants will be screened for depression and cognitive impairment, then receive screening results.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: SCREENING
Clinical trial: Use Of Oral Fidaxomicin Vs. Oral Vancomycin For Clostridium Difficile Infection In Patients With Spinal Cord Injury
Status: TERMINATED
Conditions: Clostridium Difficile|Spinal Cord Injury
Interventions: DRUG: Fidaxomicin 200 mg|DRUG: Placebo|DRUG: Vancomycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Lactobacillus Pentosus KCA1 on the Gut and Vaginal Microbiome of Women With Bacterial Vaginosis
Status: COMPLETED
Conditions: Bacterial Vaginoses
Interventions: OTHER: Lactobacillus pentosus KCA1
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Anti-parasitic Activity and Safety Assessment of SAR97276A in Children With Uncomplicated Malaria
Status: TERMINATED
Conditions: Malaria
Interventions: DRUG: SAR97276A|DRUG: arthemeter + lumefantrine (ACTs)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PHARMACODYNAMICS ASSESSMENT PRODUCT HEPARIN SODIUM (SUBCUTANEOUSLY) OF THE SWINE 5.000UI/ML OF BLAU FARMACÊUTICA S/A IN HEALTHY SUBJECTS IN COMPARISON OF SODIUM HEPARIN APP PHARMACEUTICALS
Status: UNKNOWN
Conditions: Healthy
Interventions: DRUG: Heparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Expanding Health System Intervention Through The Women, Infants and Children (WIC) Program Partnership
Status: COMPLETED
Conditions: Obesity, Childhood
Interventions: BEHAVIORAL: Pilot Intervention to reduce SSB consumption in children and families enrolled in WIC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Safety and Efficacy of Pivot Balloon to Monitoring Acute RV Failure and Reduction of FTR
Status: COMPLETED
Conditions: Functional Tricuspid Regurgitation
Interventions: DEVICE: Pivot Balloon Catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Role of the Microbiota in the Evolution of the SARS-CoV-2 Disease,COVID-19, in Hospitalized Patients
Status: UNKNOWN
Conditions: Covid19
Interventions: OTHER: oropharyngeal and intestinal microbiota|OTHER: host genotype|OTHER: host immune factors|OTHER: viral sequence
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Gene Expression During Surgical Scar Remodeling by Fractional Photothermolysis
Status: WITHDRAWN
Conditions: Hypertrophic Scars
Interventions: DEVICE: Fraxel Repair - Fractional Laser treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Multiple Ascending Dose Study to Evaluate Safety and Tolerability of BFKB8488A in Participants With Type 2 Diabetes Mellitus and Participants With Non-Alcoholic Fatty Liver Disease
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Non-Alcoholic Fatty Liver Disease
Interventions: DRUG: BFKB8488A|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Pharmacokinetics of High-Dose Rifapentine When Given as a Single Dose or in Divided Doses to Healthy Adults
Status: COMPLETED
Conditions: Tuberculosis
Interventions: DRUG: Rifapentine (RPT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lucentis for New Onset Neovascular Glaucoma
Status: WITHDRAWN
Conditions: Glaucoma|New Onset Glaucoma|Neovascular Glaucoma|New Onset Neovascular Glaucoma
Interventions: DRUG: Ranibizumab (Lucentis)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long-term Safety and Efficacy of ABT-126 in Subjects With Schizophrenia: An Extension Study for Subjects Completing Study M10-855 (NCT01655680)
Status: TERMINATED
Conditions: Schizophrenia
Interventions: DRUG: ABT-126
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: This Study Will Investigate the Efficacy and Safety of A4250 in Children With PFIC Types 1 or 2
Status: COMPLETED
Conditions: PFIC1|PFIC2
Interventions: DRUG: A4250 (odevixibat)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pelvic Belt Effects on Osseous Anatomy, Muscule Activation and Ground Reaction Forces
Status: COMPLETED
Conditions: Sacroiliac Joint Pain|Helath Related Quality of Life|Electromuscular Activation of the Pelis and Limbs|Ground Reaction Force Data
Interventions: DEVICE: Pelvic belt application
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single/ Multiple-Dose Study of E6007 in Healthy Japanese Male Subjects
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: E6007|DRUG: E6007 matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Performance of a One-step Self-etch Adhesive in Non-carious Cervical Lesions at 2 Years
Status: UNKNOWN
Conditions: Non-carious Cervical Lesions|Adhesive Performance
Interventions: PROCEDURE: Application of adhesive for the restoration of dental lesions with resin composite|PROCEDURE: Application of adhesive for the restoration of dental lesions with resin composite|PROCEDURE: Application of adhesive for the restoration of dental lesions with resin composite
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial on the Effect on Low Back Pain Related Disability of Different Health Education Programs for Retired Persons
Status: WITHDRAWN
Conditions: Low Back Pain
Interventions: BEHAVIORAL: The Back Guide|BEHAVIORAL: The Back Book|BEHAVIORAL: Cardiovascular and general health
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: A Study Evaluating Safety and Efficacy of C-CAR011 in Subjects With B-NHL
Status: UNKNOWN
Conditions: Refractory or Relapsed B-cell Non-Hodgkin Lymphoma
Interventions: BIOLOGICAL: C-CAR011
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Biologic Tumor and Plasma Biomarkers of Response to TTFields in Patients Treated for Newly Diagnosed Glioblastoma
Status: RECRUITING
Conditions: Glioblastoma
Interventions: OTHER: The samples described below will be collected:
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Efficacy and Safety Study of Eravacycline Compared With Levofloxacin in Complicated Urinary Tract Infections
Status: COMPLETED
Conditions: cUTI
Interventions: DRUG: Eravacycline|DRUG: Levofloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Incremental Vestibulo-ocular Reflex Adaptation as a Novel Treatment for Dizziness in People With Multiple Sclerosis
Status: NOT_YET_RECRUITING
Conditions: Multiple Sclerosis
Interventions: DEVICE: StableEyes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: rTSST-1 Variant Vaccine Phase 1 First-in-man Trail
Status: COMPLETED
Conditions: Toxic Shock Syndrome|Vaccination; Sepsis
Interventions: BIOLOGICAL: rTSST-1 Variant Candidate Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Irisin and Metabolic Exercise Training Study
Status: COMPLETED
Conditions: Obesity
Interventions: BEHAVIORAL: High Intensity Interval Aerobic Exercise (HIIT)|BEHAVIORAL: Continuous Moderate Aerobic Exercise (MOD)|BEHAVIORAL: Control Sitting Condition (C)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Application of Ticagrelor Combined With Low Molecular Weight Heparin During PCI
Status: UNKNOWN
Conditions: LOVASTATIN/TICAGRELOR [VA Drug Interaction]
Interventions: DRUG: Ticagrelor|DRUG: full amount low molecular weight heparin|DRUG: half amount low molecular weight heparin|DRUG: No low molecular weight heparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effects of Acute and Chronic Empagliflozin Heart Failure
Status: RECRUITING
Conditions: Heart Failure
Interventions: DRUG: Empagliflozin 10 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Manual Therapy in Patients With Neck Pain
Status: RECRUITING
Conditions: Neck Pain
Interventions: PROCEDURE: Specific joint mobilization post muscle inhibition on C1|PROCEDURE: Maitland C2|PROCEDURE: SNAG C1|PROCEDURE: Specific joint mobilization post muscle inhibition on C2|PROCEDURE: Myofascial inductions; Suboccipital induction|PROCEDURE: Myofascial inductions; Synchronization of the temporal bones PHASE 1|PROCEDURE: Myofascial inductions; Horizontal induction of the TMJ.|PROCEDURE: Myofascial inductions; Posterior elongation of the cervical fascia in the supine position|PROCEDURE: Myofascial induction; Angle of the scapula|PROCEDURE: Myofascial induction sternocleidomastoid muscles|PROCEDURE: Myofascial induction of pectoralis major and minor|PROCEDURE: Myofascial induction; upper trapezius|PROCEDURE: Myofascial induction, of the fascia of the subscapularis muscle|PROCEDURE: Intraoral myofascial induction of the masseter|PROCEDURE: Deep myofascial induction of the external pterygoid|PROCEDURE: Intraoral mifascial induction of the internal pterygoid|PROCEDURE: Myofascial inductions; Synchronization of the temporal bones PHASE 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Fertilized ACL Technique on Outcomes of ACL Reconstruction in Young Adults
Status: UNKNOWN
Conditions: ACL Tear|ACL Injury|Arthroscopy|Anterior Cruciate Ligament Tear
Interventions: PROCEDURE: ACL reconstruction with bone marrow, demineralized bone marix, and internal brace augmentation|PROCEDURE: Standard ACL reconstruction with all inside technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: RP1 in Primary Melanoma to Reduce the Risk of Sentinel Lymph Node Metastasis
Status: RECRUITING
Conditions: Melanoma
Interventions: BIOLOGICAL: Vusolimogene oderparepvec (RP1)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immune Response to Third Dose of SARS-CoV-2 Vaccine in a Cohort of Cancer Patients on Active Treatment
Status: UNKNOWN
Conditions: Sars-CoV-2 Infection
Interventions: BIOLOGICAL: Three doses of BNT162b2 (observational)|BIOLOGICAL: Two doses of Coronavac and one dose BNT162b2 (observational)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Cholinesterase Inhibitors to Slow Progression of Visual Hallucinations in Parkinson&Apos;s Disease
Status: TERMINATED
Conditions: Parkinson's Disease
Interventions: DRUG: Rivastigmine|DRUG: Placebo (for rivastigmine)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Manual Therapy and Splint Therapy in Patients With Temporomandibular Dysfunction
Status: COMPLETED
Conditions: Temporomandibular Disorder|Myofascial Pain|Bruxism
Interventions: OTHER: Manual Therapy Group|OTHER: Splint Therapy Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: RCT on Multimodal Self-treatment for Women With Incontinence Using a Digital Health Application
Status: RECRUITING
Conditions: Urinary Incontinence,Stress|Urinary Incontinence, Urge|Urinary Incontinence|Overactive Bladder Syndrome|Female Urinary Stress Incontinence
Interventions: DEVICE: Kranus Mictera
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of [18F]FLT PET/CT as an Early Predictor of Outcome in Pediatric Solid Tumors
Status: WITHDRAWN
Conditions: Solid Tumor
Interventions: DRUG: [18F]FLT-PET/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Vitamin D Status and Bone Metabolism Status in Children With Congenital Epidermolysis Bullosa
Status: UNKNOWN
Conditions: Bullosa Epidermolysis|Vitamin D Deficiency|Osteoporosis|Osteopenia|Phosphorus and Calcium Disorders
Interventions: DRUG: Vitamin D|DIETARY_SUPPLEMENT: Oral nutritional supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Preliminary Study to Evaluate PF-07264660 in Healthy Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: PF-07264660 intravenous single ascending dose|DRUG: PF-07264660 subcutaneous multiple ascending dose|OTHER: Intravenous placebo|OTHER: subcutaneous placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of a Single Intravenous Infusion Dose of TAK-925 in Participants With Idiopathic Hypersomnia
Status: COMPLETED
Conditions: Idiopathic Hypersomnia
Interventions: DRUG: TAK-925|DRUG: TAK-925 Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cervical Ripening: A Comparison Between Intravaginal Misoprostol Tablet and Intracervical Foley's Catheter and Subsequent Induction of Labor, Safety and Efficacy in Federal Teaching Hospital Abakaliki, Ebonyi State, Nigeria.
Status: COMPLETED
Conditions: Cervical Ripening and Induction of Labor
Interventions: DEVICE: Foley's Catheter|DRUG: prostaglandin E1 analogue
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: MDMA in Subjects With Moderate Hepatic Impairment and Subjects With Normal Hepatic Function
Status: NOT_YET_RECRUITING
Conditions: Pharmacokinetics|Hepatic Impairment
Interventions: DRUG: Midomafetamine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Gait Analysis and Gait Training in Patient With Total Hip or Total Knee Replacement
Status: RECRUITING
Conditions: Arthroplasty, Replacement, Knee|Arthroplasty, Replacement, Hip
Interventions: OTHER: Gait training with real time biofeedback
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Fluoride Varnish in the Prevention of Early Childhood Caries: A Randomized Controlled Trial
Status: COMPLETED
Conditions: Dental Caries
Interventions: OTHER: Fluoride varnish plus education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of the Effectiveness of Green Diode Laser Light on Body Shaping
Status: COMPLETED
Conditions: Body Contouring
Interventions: DEVICE: Erchonia GLS|DEVICE: Placebo laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Heart Rate on Cardiac Index in Patients With Left Ventricular Hypertrophy
Status: TERMINATED
Conditions: Left Ventricular Hypertrophy|Diastolic Dysfunction|Heart Failure|Heart Rate
Interventions: DEVICE: Pacemaker
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Study to Investigate the Effect of a Single Dose of AZD7624 on Inflammation Caused by an Endotoxin Challenge
Status: COMPLETED
Conditions: LPS Challenge, Neutrophils
Interventions: DRUG: AZD7624|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of Fedratinib With IDH Inhibition in Advanced-Phase, IDH-Mutated Ph-Negative Myeloproliferative Neoplasms
Status: WITHDRAWN
Conditions: IDH Mutation|IDH1 Mutation|IDH2 Gene Mutation|Blood Cancer|Myeloproliferative Neoplasm
Interventions: DRUG: Ivosidenib|DRUG: Enasidenib|DRUG: Fedratinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bedtime Potassium Losartan on CKD With Nocturnal Hypertension Patients With Nondipping Blood Pressure Pattern
Status: UNKNOWN
Conditions: Chronic Kidney Disease Patients
Interventions: DRUG: potassium losartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Total Knee Arthroplasty Comparing Cementless to Cemented Fixation
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DEVICE: Cementless (Nexgen)|DEVICE: Cemented (Nexgen)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Modified-release Dipyridamole/Aspirin (200mg/25mg bd) Versus Aspirin (75mg) in Aspirin-resistant Patients
Status: COMPLETED
Conditions: Coronary Arteriosclerosis
Interventions: DRUG: modified-release dipyridamole/aspirin|DRUG: aspirin
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Effect of 12 wk of Omega-3 FA Supplementation on Metabolic and Physical Health Parameters in Older Adults
Status: UNKNOWN
Conditions: Effect of Omega-3 Fatty Acid Supplementation Physical Fitness
Interventions: DIETARY_SUPPLEMENT: Omega-3 Complete|DIETARY_SUPPLEMENT: Placebo capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Ketogenic Diet in People With Schizophrenia
Status: RECRUITING
Conditions: Schizophrenia|Schizo Affective Disorder
Interventions: OTHER: Regular Diet|OTHER: Ketogenic Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SPIRITT - Second-Line Panitumumab Irinotecan Treatment Trial
Status: COMPLETED
Conditions: Cancer|Colon Cancer|Colorectal Cancer|Metastatic Cancer|Rectal Cancer|Metastatic Colorectal Cancer
Interventions: DRUG: Panitumumab|DRUG: Bevacizumab|DRUG: Leucovorin|DRUG: Irinotecan|DRUG: 5-Fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Machine Learning and 3D Image-based Modeling for Body Weight Estimation.
Status: NOT_YET_RECRUITING
Conditions: No Specific Conditions|Weight, Body|Drug Dose|Weight-Estimation
Interventions: OTHER: Weight estimation using 3D camera|OTHER: Standard care weight estimation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: AIRE-2 Device for Study of Breath Analysis in IBD
Status: NOT_YET_RECRUITING
Conditions: Inflammatory Bowel Diseases
Interventions: DIETARY_SUPPLEMENT: low FODMAP diet|DIETARY_SUPPLEMENT: Lactose Sachet|DIETARY_SUPPLEMENT: Fructose Sachet|DIETARY_SUPPLEMENT: Sorbitol Sachet|DIETARY_SUPPLEMENT: Inulin Sachet|DEVICE: AIRE-2 Portable breath analyzer
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: ABX464 in Treating Inflammation and Preventing Acute Respiratory Failure in Patients With COVID-19
Status: TERMINATED
Conditions: COVID-19
Interventions: DRUG: ABX464|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective Identification of Predictive Biomarkers of Trabectedin Efficacy in Non-L Soft-tissue Sarcoma Patients
Status: RECRUITING
Conditions: Soft Tissue Sarcoma Adult|Undifferentiated Pleomorphic Sarcoma|Epithelioid Sarcoma|Solitary Fibrous Tumors|Hemangioendothelioma|Desmoplastic Round Cell Tumor|Synovial Sarcoma
Interventions: DRUG: Trabectedin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Inferior Turbinate Surgery in Rhinoseptoplasty: a Randomized Clinical Trial With Quality of Life Outcomes
Status: COMPLETED
Conditions: Nasal Obstruction|Rhinoplasty|Rhinoseptoplasty|Turbinate Surgery|Quality of Life
Interventions: PROCEDURE: Inferior turbinate surgery|PROCEDURE: No iInferior turbinate surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Platelet Rich Plasma for Insufficient Endometrium
Status: RECRUITING
Conditions: Infertility of Uterine Origin
Interventions: OTHER: Platelet Rich Plasma Intrauterine infusion|OTHER: Normal saline Intrauterine infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Post Market Clinical Follow-up of Dual-mobility Acetabular Cup EUROSCUP MOBILE
Status: ACTIVE_NOT_RECRUITING
Conditions: Hip Arthropathy|Hip Osteoarthritis|Hip Arthritis|Hip Fractures|Hip Necrosis|Hip Dysplasia
Interventions: DEVICE: hip arthroplasty
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Multifaceted Treatment of Catheter-related Urinary Tract Infection
Status: COMPLETED
Conditions: Spinal Cord Injury|Neurogenic Bladder|Urinary Tract Infection
Interventions: OTHER: Shortened course of antibiotic therapy|OTHER: Standard Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Alternate Day vs. Daily Iron Supplementation in Iron Depleted Women
Status: COMPLETED
Conditions: Iron-deficiency|Iron Deficiency Anemia
Interventions: DIETARY_SUPPLEMENT: Consecutive Day Dosing|DIETARY_SUPPLEMENT: Alternate Day Dosing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Local Consolidative Therapy and Brigatinib in Treating Patients With Stage IV or Recurrent Non-small Cell Lung Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Lung Carcinoma|ALK Gene Rearrangement|Lung Non-Small Cell Carcinoma|Recurrent Lung Non-Small Cell Carcinoma|Stage IV Lung Cancer AJCC v8|Stage IVA Lung Cancer AJCC v8|Stage IVB Lung Cancer AJCC v8
Interventions: DRUG: Brigatinib|PROCEDURE: Local Consolidation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cardiac Resynchronization Therapy (CRT)-Narrow-dp/Dt-Study
Status: COMPLETED
Conditions: Heart Failure
Interventions: PROCEDURE: LV dp/dt pressure measurement|PROCEDURE: LV dp/dt pressure measurement
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Prophylactic Manual Rotation of Persistent Occiput Posterior Presentation During the Early Second Stage of Labor to Reduce Operative Delivery: a Prospective Multicenter Randomized Control Trial
Status: UNKNOWN
Conditions: Persistent Occipital Posterior Presentation During Labor Delivery
Interventions: PROCEDURE: Prophylactic Manual Rotation of persistent occipital posterior presentation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, and Pharmacokinetics of SAB-176 in Healthy Participants
Status: UNKNOWN
Conditions: Influenza Type A|Influenza Type B|Influenza
Interventions: BIOLOGICAL: SAB-176|OTHER: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study on the Optimal Strategy for Acute-on-chronic Liver Failure With Integrative Treatment
Status: COMPLETED
Conditions: Acute on Chronic Liver Failure|Traditional Chinese Medicine|Hepatitis B
Interventions: DRUG: Chinese herbal medicine|OTHER: Control (blank)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Enzalutamide in Patients With Advanced, Androgen Receptor-Positive, Triple Negative Breast Cancer
Status: COMPLETED
Conditions: Advanced, Androgen Receptor Positive Triple Negative Breast Cancer
Interventions: DRUG: Enzalutamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: LEO 90100 in the Treatment of Psoriasis Vulgaris
Status: COMPLETED
Conditions: Psoriasis Vulgaris
Interventions: DRUG: LEO 90100|DRUG: Calcipotriol|DRUG: Betamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dual Antiplatelet Therapy in Patients With Clopidogrel Resistance Following Off-Pump Coronary Artery Bypass
Status: UNKNOWN
Conditions: Multi Vessel Coronary Artery Disease
Interventions: DRUG: Ticagrelor|DRUG: Clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Efficacy of AVP-786 for the Treatment of Disinhibition
Status: TERMINATED
Conditions: Disinhibition Syndrome
Interventions: DRUG: AVP-786|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: REmote Assessment and Dynamic Response Intervention II
Status: COMPLETED
Conditions: Dementia|Alzheimer Disease|Relationship, Marital|Caregiver Stress Syndrome
Interventions: BEHAVIORAL: READyR II: A|BEHAVIORAL: READyR II: B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Identifying Treatments to Motivate Smokers to Quit
Status: COMPLETED
Conditions: Smoking|Smoking Cessation|Motivation|Nicotine Dependence
Interventions: DRUG: Nicotine Patch|DRUG: Nicotine Gum|BEHAVIORAL: Motivational Interviewing|BEHAVIORAL: Smoking Reduction|OTHER: No Intervention|DRUG: Nicotine Patch + Nicotine Gum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare a New Long-Acting Insulin (LY2605541) and Human Insulin NPH in Participants With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: LY2605541|DRUG: Human Insulin NPH|DRUG: Oral Antihyperglycemic Medications (OAM)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ranibizumab Intravitreal Injections Versus Sham Control in Patients With Branch Retinal Vein Occlusion (BRVO)
Status: COMPLETED
Conditions: Macular Edema Secondary to Branch Retinal Vein Occlusion
Interventions: DRUG: Ranibizumab 0.5 mg|OTHER: Sham injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Kinematic Analysis: Posterior Stabilized, Fixed Bearing Total Knee Arthroplasty With Attune Knee System - Phase 2
Status: COMPLETED
Conditions: Total Knee Arthroplasty|Osteoarthritis
Interventions: DEVICE: DePuy Attune posterior stabilizing fixed bearing knee system
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study to Assess Safety, Tolerability and Efficacy of MB-106 in Patients With Relapsed or Refractory B-Cell NHL or CLL
Status: TERMINATED
Conditions: Follicular B-cell Non-Hodgkin's Lymphoma|Mantle Cell Lymphoma Recurrent|Mantle Cell Lymphoma Refractory|Small Lymphocytic Lymphoma, Relapsed|Waldenstrom's Macroglobulinemia Recurrent|Waldenstrom's Macroglobulinemia Refractory|Chronic Lymphoid Leukemia in Relapse|B-cell Lymphoma Refractory
Interventions: BIOLOGICAL: MB-106
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neurogenetic Pharmaceuticals (NGP) 555 in Healthy Volunteers (14 Day Multiple Ascending Dose)
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: NGP 555
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Modified Limberg Procedure Versus Lateral Advancement Flap With Burrow's Triangle Procedure in the Treatment of Pilonidal Sinus
Status: COMPLETED
Conditions: Sacrococcygeal Pilonidal Disease
Interventions: PROCEDURE: Flap Transposition Procedures
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy Followed By Surgery Vs Radiotherapy Plus Chemotherapy in Patients With Stage IB or II Cervical Cancer
Status: UNKNOWN
Conditions: Cervical Cancer
Interventions: PROCEDURE: conventional surgery|PROCEDURE: neoadjuvant chemotherapy|RADIATION: brachytherapy|RADIATION: radiation therapy|DRUG: cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multi-center Clinical Study on Hemoperfusion of KHA80
Status: NOT_YET_RECRUITING
Conditions: Uremia|Uremic Osteodystrophy|Dialysis Related Complication
Interventions: DEVICE: KHA80 hemoperfusion treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Glucosamine Sulphate and Ginkgo Biloba as Antifungal Activity for Treating Tinea Pedis
Status: UNKNOWN
Conditions: Foot Infection Tinea Pedis
Interventions: DRUG: infected group|DRUG: control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Percutaneous Kyphoplasty Using Rotary Cutter in Osteoporotic Vertebral Fractures
Status: UNKNOWN
Conditions: Spine Fracture
Interventions: DEVICE: Conventional Kyphoplasty|DEVICE: Kyphoplasty with Rotary Cutter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Efficacy and Safety of Ferrlecit in the Maintenance Dosing in Hemodialysis Patients.
Status: TERMINATED
Conditions: Anemia
Interventions: DRUG: Oral Iron|DRUG: sodium ferric gluconate|DRUG: sodium ferric gluconate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Study on the Effect of Quadratus Lumborum Block Versus Intrathecal Morphine on the Incidence of Chronic Pain Post Caesarean Section in a University Hospital of Middle-income Country
Status: COMPLETED
Conditions: Chronic Post Cesarean Pain
Interventions: PROCEDURE: Quadratus laborum block|DRUG: Intrathecal morphine|DRUG: intrathecal bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing the Efficacy and Safety of Fremanezumab (TEV-48125) for the Prevention of Chronic Cluster Headache (CCH)
Status: TERMINATED
Conditions: Chronic Cluster Headache
Interventions: DRUG: Fremanezumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study To Assess The Bioequivalence Under Fed And Fasted Conditions Of The Fesoterodine Beads-In-Capsule SR4 And SR7 Formulations And To Estimate The Bioavailability of SR7 Beads Sprinkled On Apple Sauce Relative To The Beads-In-Capsule SR7 Formulation Administer
Status: COMPLETED
Conditions: Neurogenic Detrusor Overactivity
Interventions: DRUG: Fesoterodine BIC SR4 fasted (Treatment A in Part A, Treatment G in Part B)|DRUG: Fesoterodine BIC SR7 fasted (Treatment B in Part A, Treatment H in Part B)|DRUG: Fesoterodine BIC SR7 fed (Treatment C in Part A, Treatment F in Part B)|DRUG: Fesoterodine BIC SR7 on apple sauce (Treatment D in Part A)|DRUG: Fesoterodine BIC SR4 fed (Treatment E in Part B)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Clinical Study to Evaluate the Pharmacokinetics of Lozanoc and Sporanox in Korean Healthy Male Volunteers
Status: COMPLETED
Conditions: Superficial Mycoses|Dermatomycoses|Candidiasis|Histoplasmosis
Interventions: DRUG: Lozanoc 50mg|DRUG: Sporanox 100mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Safety and Tolerability Study of SKX-16 in Subjects With Moderate to Severe Distal Subungual Onychomycosis
Status: UNKNOWN
Conditions: Onychomycosis of Toenail
Interventions: DRUG: SKX-16 (Luliconazole 10% Solution)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Study Assessing the Safety and Tolerability of CTX-4430
Status: COMPLETED
Conditions: Pulmonary Inflammation
Interventions: DRUG: CTX-4430|OTHER: Mannitol|DRUG: Placebo|DRUG: CTX-4430|DRUG: Placebo|OTHER: Mannitol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Early Provision of Enteral Microlipid and Fish Oil to Infants With Enterostomy
Status: COMPLETED
Conditions: Short Bowel Syndrome|Necrotizing Enterocolitis|Small Intestine Perforation
Interventions: DIETARY_SUPPLEMENT: MicroLipid and fish oil|OTHER: Routine care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Phase 3 Long-term Study of TAK-536 in Pediatric Patients 6 to Less Than 16 Years With Hypertension
Status: COMPLETED
Conditions: Pediatric Hypertension
Interventions: DRUG: Azilsartan|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Home-based Exercice Therapy for Patients With Intermittent Claudication Using a New Smartphone Application
Status: RECRUITING
Conditions: Intermittent Claudication
Interventions: OTHER: E-REVA® app|OTHER: No E-REVA® app
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Complex Decongestive Therapy, Cryotherapy and Kinesio Taping in Patients With Post-mastectomy Lymphedema: A Randomized Control Trial
Status: RECRUITING
Conditions: Breast Neoplasms
Interventions: OTHER: Complex decongestive therapy|DEVICE: Cryotherapy|OTHER: Kinesio taping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Flash Glucose-Sensing Technology on the Occurrence of Cardiac Arrhythmias Associated With Hypoglycemia
Status: UNKNOWN
Conditions: Insulin Treated Type 2 Diabetes With High Risk of Hypoglycemia
Interventions: DEVICE: FREESTYLE LIBRE device, a Flash Continuous Glucose Monitoring System|DEVICE: Usual self monitoring Blood Glucose device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Tepotinib in Solid Tumors Harboring MET Alterations
Status: UNKNOWN
Conditions: Solid Tumor|MET Exon 14 Skipping Mutation|MET Amplification
Interventions: DRUG: Tepotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Ipratropium / Levosalbutamol Fixed Dose Combination and Ipratropium and Levosalbutamol Free Dose Combination Nebuliser Solutions in Stable Chronic Obstructive Pulmonary Disease (COPD) Patients
Status: RECRUITING
Conditions: COPD
Interventions: DRUG: Ipratropium / Levosalbutamol Fixed Dose Combination|DRUG: Ipratropium + Levosalbutamol Free Dose Combination
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Promoting Health LongevIty Through Mitigation and Prevention of Frailty in Community-dwelling Elderly (Pro-LIFE)
Status: UNKNOWN
Conditions: Frailty|Frailty Syndrome
Interventions: BEHAVIORAL: Pre-frail intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Quality of Sleep of Patients With Predominant Central Sleep Apnea Syndrome(SAS) Whose EF > 45% Treated by ASV
Status: ACTIVE_NOT_RECRUITING
Conditions: Central Sleep Apnea Syndrome in Patients Whose EF is Above 45 Percent
Interventions: DEVICE: Adaptative Servo Ventilation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Does the Diacutaneous Fibrolysis Change Ultrasonographic Measurements in Patients With Carpal Tunnel Syndrome?
Status: COMPLETED
Conditions: Carpal Tunnel Syndrome|Physical Therapy Modalities|Ultrasonography
Interventions: OTHER: Diacutaneous Fibrolysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Adherence Support Intervention for Persons Living With HIV/AIDS (PLWHA) on Antiretroviral Therapy (ART) in Estonia
Status: COMPLETED
Conditions: HIV|AIDS|Medication Adherence
Interventions: BEHAVIORAL: Situated Optimal Adherence Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparative Study of Specular Microscopes for Measurements of Cell Density, Coefficient of Variation and Hexagonality
Status: COMPLETED
Conditions: Corneal Endothelial Cell Loss
Interventions: DEVICE: Specular Microscope Nidek CEM-530|DEVICE: Specular Microscope Konan CELLCHEK XL
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Monoamine Antagonist Therapies for Methamphetamine Abuse Prazosin
Status: COMPLETED
Conditions: Continuous Methamphetamine Abuse
Interventions: DRUG: Prazosin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Phase II Study to Evaluate Efficacy and Safety of AMP Peptide PL-5 in Mild Infections of Diabetic Foot Ulcers
Status: NOT_YET_RECRUITING
Conditions: Diabetic Foot Ulcers
Interventions: DRUG: Antimicrobial Peptide PL-5 Topical Spray and Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating an Online Adjunctive Support Following Intensive Services (OASIS) Strategy for Youth With Selective Mutism
Status: COMPLETED
Conditions: Selective Mutism
Interventions: BEHAVIORAL: Remote Caregiver Training|BEHAVIORAL: Remote Intensive Group Behavioral Treatment (IGBT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Role of the Circadian System in Neurological Sleep-wake Disorders
Status: COMPLETED
Conditions: Narcolepsy 1|Idiopathic Hypersomnia
Interventions: BEHAVIORAL: Sleep restriction|BEHAVIORAL: Sleep deprivation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Safety Study of Prucalopride for the Re-Treatment of Chronic Constipation
Status: COMPLETED
Conditions: Constipation
Interventions: DRUG: Prucalopride|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Donepezil on Glycemic Control in Type II Diabetics
Status: TERMINATED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Donepezil 5-10 Mg Oral Tablet|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess PK, PD, Nicotine Extraction, Palatability, Subjective Effects of Nicotine Pouches - Daily Nicotine Users
Status: RECRUITING
Conditions: Nicotine Use Disorder
Interventions: OTHER: Test product 1 - Test product 2 - Comparator product
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Rehabilitating Muscle After Intensive Care
Status: COMPLETED
Conditions: Recovery From Critical Illness
Interventions: DIETARY_SUPPLEMENT: Amino acid supplement|OTHER: PEPSE|OTHER: Intensive Care Unit (ICU) Recovery Manual|DIETARY_SUPPLEMENT: Placebo nutritional supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT