pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Effectiveness of Focused Tele-education in Reducing Diabetes Complications During Ramadan
Status: RECRUITING
Conditions: Diabetes Mellitus|Fasting|Diabetes Complications
Interventions: COMBINATION_PRODUCT: Focused diabetes tele-education and medication adjustment based on guidelines with remote monitoring from trial of fasting from before to throughout Ram
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Selective Estrogen Receptor Modulators - A Potential Treatment for Psychotic Symptoms of Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder|Schizophreniform Disorder
Interventions: DRUG: Raloxifene hydrochloride|OTHER: Lactose Capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Amgen Megakaryopoiesis Protein 2 (AMG 531) in Thrombocytopenic Subjects With Immune Thrombocytopenic Purpura (ITP)
Status: COMPLETED
Conditions: Thrombocytopenic Purpura
Interventions: DRUG: Romiplostim
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and PD Activity of Inhaled TPI 1020 Versus Inhaled Budesonide in COPD Patients
Status: COMPLETED
Conditions: Copd Bronchitis
Interventions: DRUG: TPI 1020|DRUG: Budesonide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Personalized Voice Restoration Device for Patients With Laryngectomy
Status: NOT_YET_RECRUITING
Conditions: Dysphonia|Aphonia
Interventions: DEVICE: Surface Electromyography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Impact of Radical Prostatectomy as Primary Treatment in Patients With Prostate Cancer With Limited Bone Metastases
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Cancer
Interventions: PROCEDURE: Radical prostatectomy|DRUG: Best systemic therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of N-acetylcysteine on Alleviating Symptom Caused by Lugol Chromoendoscopy
Status: COMPLETED
Conditions: Esophageal Squamous Cell Carcinoma
Interventions: DRUG: N-acetylcysteine solution|DRUG: sodium thiosulfate solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Adherence, Efficacy and Safety of an Insulin Protocol in the Critically Ill: A Prospective Observational Study
Status: COMPLETED
Conditions: Critically Ill Patients
Interventions: DRUG: to implement an insulin protocol with target blood glucose levels between 81-110 mg/dL.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lurasidone Effects on Tissue Glutamate in Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder
Interventions: DRUG: Lurasidone|DRUG: Haloperidol|DRUG: Perphenazine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Two Nasal Products Based on Diluted Seawater in the Treatment of Upper Respiratory Infections/Conditions
Status: NOT_YET_RECRUITING
Conditions: Rhinitis|Sinusitis|Upper Respiratory Infections|Colds
Interventions: OTHER: administration of an isotonic seawater solution (9g/L) in the nose|OTHER: administration of a hypertonic seawater solution (21g/L) in the nose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Japanese Encephalitis Chimeric Virus Vaccine Given With Measles-Mumps-Rubella Vaccine in Taiwanese Toddlers
Status: COMPLETED
Conditions: Japanese Encephalitis|Measles|Mumps|Rubella
Interventions: BIOLOGICAL: Japanese encephalitis chimeric virus: Measles, mumps, and rubella live attenuated virus|BIOLOGICAL: Japanese encephalitis chimeric virus: Measles, mumps, and rubella live attenuated virus|BIOLOGICAL: Japanese encephalitis chimeric virus: Measles, mumps, and rubella live attenuated virus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate Pneumococcal Polysaccharide Vaccine Effectiveness in Children With Type 1 Diabetes
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: BIOLOGICAL: Pneumovax 23- pneumococcal polysaccharide|PROCEDURE: Blood draw
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Mediterranean Diet Plus Extravirgin Olive Oil in the Prevention of Recurrent Arrhythmias. The PREDIMAR (PREvención Con DIeta Mediterránea de Arritmias Recurrentes) Trial
Status: UNKNOWN
Conditions: Atrial Fibrillation|Atrial Arrhythmia
Interventions: DIETARY_SUPPLEMENT: Mediterranean diet plus extra virgin olive oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Calanus Oli on Intra-abdominal Fat, Glucose Tolerance and Lipids in Man
Status: COMPLETED
Conditions: Overweight
Interventions: DIETARY_SUPPLEMENT: calanus oil|DIETARY_SUPPLEMENT: olive oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Two-Step Approach to Bone Marrow Transplant Using Cells From A Partially-Matched Relative
Status: COMPLETED
Conditions: Hematologic Malignancies
Interventions: RADIATION: Total Body Irradiation (TBI)|BIOLOGICAL: Donor Lymphocyte Infusion (DLI)|DRUG: Cyclophosphamide (CY)|DRUG: Tacrolimus|DRUG: Mycophenolate Mofetil (MMF)|BIOLOGICAL: Hematopoietic Stem Cell Transplant (HSCT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cold EMR Vs Standard EMR for the Treatment of Large Nonpedunculated Homogeneous Colorectal Lesions
Status: COMPLETED
Conditions: Adenoma Colon|Serrated Polyp|Serrated Adenoma|Colorectal Neoplasms
Interventions: PROCEDURE: Standard Endoscopic Mucosal Resection|PROCEDURE: Cold Snare Endoscopic Mucosal Resection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cytokine Profiles in Breast Cancer Patients Undergoing Chemotherapy
Status: COMPLETED
Conditions: Mammary Neoplasm, Human|Periodontal Diseases|Chemotherapy Effect
Interventions: PROCEDURE: Non surgical periodontal Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Azacitidine and Lintuzumab in Treating Patients With Previously Untreated Myelodysplastic Syndromes
Status: TERMINATED
Conditions: Leukemia|Myelodysplastic Syndromes
Interventions: BIOLOGICAL: lintuzumab|DRUG: 5-azacytidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: NAC, NaHCO3 and NS Prophylaxis for CTPA in the ED on Suspicion of PE: A Randomized Controlled Trial
Status: COMPLETED
Conditions: Radiographic Contrast Agent Nephropathy|Pulmonary Embolism
Interventions: DRUG: NAC|DRUG: NaHCO3|DRUG: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Safety, Tolerability, and Pharmacokinetics (PK) Study of AGN-223575 in Healthy Subjects
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: AGN-223575 Formulation A|DRUG: AGN-223575 Formulation B|DRUG: AGN-223575 Formulation C|DRUG: AGN-223575 Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety Study of 2 Formulations of GSK's Human Rotavirus (HRV) Vaccine (444563), in Healthy Infants Starting at Age 6-12 Weeks
Status: COMPLETED
Conditions: Infections, Rotavirus
Interventions: BIOLOGICAL: PCV-free liquid formulation of GSK's oral live attenuated HRV vaccine|BIOLOGICAL: Lyophilized formulation of GSK's oral live attenuated HRV vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparative Study of the Efficacy and Safety of BCD-131 and Mircera in Treatment of Anemia in CKD Patients on Dialysis
Status: COMPLETED
Conditions: Anemia
Interventions: BIOLOGICAL: BCD-131|BIOLOGICAL: Mircera
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Trial on Adjuvant Chemotherapy in Colon Carcinoma Dukes B
Status: COMPLETED
Conditions: Colon Cancer Stage II
Interventions: DRUG: Fluorouracil|DRUG: Leucovorin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Mebo Dressing Versus Standard Care on Managing Donor and Recipient Sites of Split-thickness Skin Graft
Status: UNKNOWN
Conditions: Burns
Interventions: DRUG: Moist Exposed Burn Ointment (MEBO)|DRUG: Zagazig
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of an Invasive Physical Therapy Protocol in Carpal Tunnel Syndrome: Randomized Controlled Clinical Trial
Status: NOT_YET_RECRUITING
Conditions: Carpal Tunnel Syndrome
Interventions: OTHER: Invasive Physiotherapy|OTHER: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of TENS for Ocular Pain
Status: ACTIVE_NOT_RECRUITING
Conditions: Eye Pain
Interventions: DEVICE: Active Cefaly Dual (R)|DEVICE: Sham Cefaly Dual (R)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Adjunctive Treatment of Major Depression Utilizing Auricular Acupuncture
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DEVICE: Auricular Acupuncture|DRUG: Sham Auricular Acupuncture + Lexapro
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Does Semaglutide Reduce Alcohol Intake in Patients With Alcohol Use Disorder and Comorbid Obesity?
Status: RECRUITING
Conditions: Alcohol Abuse|Alcohol Addiction|Alcohol Dependence|Alcohol Use Disorder
Interventions: DRUG: Semaglutide Injectable Product|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare PK, PD and Safety of the AD-214 10/600mg and Rabeprazole
Status: COMPLETED
Conditions: Gastroesophageal Reflux Disease
Interventions: DRUG: AD-214 10/600mg|DRUG: Rabeprazole 10mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: "Dumpling Suture Method" Versus Traditional Suture Method of Protective Loop Ileostomy in Laparoscopic Anterior Rectal Resection With Specimen Extraction Via Stoma: a Retrospective Comparative Study
Status: COMPLETED
Conditions: Ileostomy; Complications
Interventions: PROCEDURE: Suturing of ileostomy using "Dumpling suture method"|PROCEDURE: Suturing of ileostomy using Traditional suture method
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: An Effective and Well-Tolerated Regimen of Docetaxel Plus High-Dose 5-Fluorouracil and Leucovorin(HDFL)to Treat Inoperable Advanced or Metastatic Gastric Cancer
Status: UNKNOWN
Conditions: Stomach Neoplasms
Interventions: DRUG: Taxotere, Fluorouracil, Leucovorin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Confirm the Safety and Efficacy of Tegoprazan in Patients With Healed Erosive Reflux Disease
Status: COMPLETED
Conditions: Erosive Reflux Disease
Interventions: DRUG: Tegoprazan 50mg QD|DRUG: Lansoprazole 30mg QD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Advanced Neuroimaging Evaluation of CNS Changes Associated With Efavirenz Therapy Switch to an Raltegravir-based Regimen
Status: COMPLETED
Conditions: HIV|HIV-associated Neurocognitive Disorder|Neurotoxicity
Interventions: DRUG: Raltegravir
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Rivaroxaban Versus Low-molecular-weight Heparin for Preventing Thrombosis in Cancer Patients
Status: COMPLETED
Conditions: Neoplasms
Interventions: DRUG: Rivaroxaban 10 MG|DRUG: Rivaroxaban 20 MG|DRUG: Low-molecular-weight heparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of Multiple Ascending Doses of GSBR-1290 in Japanese and Non-Japanese Healthy Participants
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: GSBR-1290|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Buprenorphine/Naloxone in Treating Opioid Dependent Individuals Who Are Maintained on Methadone
Status: TERMINATED
Conditions: Opioid-Related Disorders
Interventions: DRUG: Buprenorphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Efficacy of Cannabidiol in Patients With Multiple Myeloma, Glioblastoma Multiforme, and GI Malignancies
Status: UNKNOWN
Conditions: Cancer of Pancreas|Cancer of Liver|Cancer of Rectum|Cancer of Colon|Cancer, Gall Bladder|Myeloma Multiple|Glioblastoma Multiforme
Interventions: DRUG: Cannabidiol|DRUG: Bortezomib|DRUG: Leucovorin|DRUG: 5-FU|DRUG: Oxaliplatin|DRUG: Bevacizumab|DRUG: Irinotecan|DRUG: Gemcitabine|DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ovarian Stimulation and Intrauterine Insemination in Women With Polycystic Ovarian Syndrome
Status: COMPLETED
Conditions: Infertility|Polycystic Ovarian Syndrome|Intrauterine Insemination
Interventions: PROCEDURE: Intrauterine insemination (IUI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Laparoscopy Heller Myotomy With Fundoplication Associated Versus Peroral Endoscopic Myotomy (POEM)
Status: UNKNOWN
Conditions: Dysphagia|Achalasia
Interventions: PROCEDURE: Endoscopic surgery|PROCEDURE: Laparoscopic surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Exploring Efficacy of SIBP04 in Subjects With Non-squamous Non-small Cell Lung Cancer
Status: COMPLETED
Conditions: Non-squamous Non-small-cell Lung Cancer
Interventions: DRUG: SIBP04|DRUG: Avastin|DRUG: Paclitaxel|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study to Evaluate the Use of the AMMA Portable Scalp Cooling System From Cooler Heads
Status: WITHDRAWN
Conditions: Alopecia|Chemotherapy-induced Alopecia|Hair Loss|Breast Cancer|Gynecologic Cancer
Interventions: DEVICE: AMMA Portalbe Scalp Cooling System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Study to Evaluate Patient Outcome Using Distal Protection Combined With the BX Velocity.
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DEVICE: emboli capturing guidewire device combined with stent
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Cohort Study of COVID-19 mRNA Vaccine, Bivalent in Participants in China
Status: UNKNOWN
Conditions: SARS-CoV-2
Interventions: BIOLOGICAL: SARS-CoV-2 mRNA Vaccine, Bivalent Low dose|BIOLOGICAL: SARS-CoV-2 mRNA Vaccine, Bivalent High dose|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Dose Escalation Study to Assess Safety of GSK2256098 (FAK Inhibitor) in Combination With Trametinib (MEK Inhibitor) in Subjects With Advanced Solid Tumors
Status: COMPLETED
Conditions: Cancer|Neoplasms
Interventions: DRUG: GSK2256098|DRUG: Trametinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tympanoplasty Using Conchal Cavum Approach and Conchal Pericondrium
Status: COMPLETED
Conditions: Perforation of Eardrum.
Interventions: PROCEDURE: tympanoplasty -- conchal cavum approach
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Clinical Efficacy and Safety of "Medifoam H" in Wound Healing
Status: COMPLETED
Conditions: Trauma
Interventions: DEVICE: Medifoam H dressing|DEVICE: Duoderm THIN dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Bronchodilator Nebulization With and Without Noninvasive Ventilation in COPD
Status: TERMINATED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)|Type 2 Respiratory Failure
Interventions: PROCEDURE: In-line nebulization through NIV mask|PROCEDURE: Off-NIV nebulization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Worksite Wellness Within Long-term Care Facilities
Status: ACTIVE_NOT_RECRUITING
Conditions: Worksite Health Promotion|Lifestyle Risk Reduction|Cardiovascular Diseases|Occupational Stress|Healthcare Workers
Interventions: BEHAVIORAL: WHHIP PLUS|BEHAVIORAL: Education only control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Mycophenolate Mofetil Versus Azathioprine in Treatment Naive Autoimmune Hepatitis
Status: UNKNOWN
Conditions: Autoimmune Hepatitis
Interventions: DRUG: Mycophenolate mofetil|DRUG: Azathioprine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Outcomes of Bilateral Temporomandibular Joint Arthroscopy and the Role of a Second Intervention - Timings and Results
Status: COMPLETED
Conditions: Bilateral Temporomandibular Joint Disorder
Interventions: PROCEDURE: bilateral temporomandibular joint arthroscopy|DRUG: Xeomin® (Merz)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mobile Video Education to Improve Patient Clinician Communication During Prenatal Clinic Visits
Status: NOT_YET_RECRUITING
Conditions: Patient Empowerment
Interventions: OTHER: Video Intervention|OTHER: Webpage links
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Continuous Rhythm Monitoring in Patients After Acute Myocardial infaRction andpREServed Lef venTricle Ejection Fraction (ARREST)
Status: COMPLETED
Conditions: Myocardial Infarction
Interventions: DEVICE: PCI|DEVICE: ILR implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Validation of the Critical-Care Pain Observation Tool (CPOT) in the Greek Population
Status: SUSPENDED
Conditions: Pain|Intensive Care Units
Interventions: DIAGNOSTIC_TEST: Critical care pain observation tool
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Safety and Efficacy of Venetoclax, Cytarabine and Metformin (VenCM) for Relapsed-Refractory and Induction-Ineligible Acute Myeloid Leukemia
Status: RECRUITING
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Venetoclax|DRUG: Cytarabine Injection|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Laser Ablation in the Treatment of High-grade Cervical Lesions
Status: NOT_YET_RECRUITING
Conditions: High-Grade Squamous Intraepithelial Lesions
Interventions: PROCEDURE: laser ablation|PROCEDURE: LEEP or Conization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevention of Post-Operative Shivering
Status: COMPLETED
Conditions: Post-Operative Shivering
Interventions: DRUG: paracetamol|DRUG: ondansetron|DRUG: normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Can HER2 Targeted PET/CT Imaging Identify Unsuspected HER2 Positive Breast Cancer Metastases, Which Are Amenable to HER2 Targeted Therapy?
Status: COMPLETED
Conditions: Breast Cancer Metastases|HER2 Positive Breast
Interventions: RADIATION: 89Zr-trastuzumab|DEVICE: PET/CT scan|RADIATION: 89Zr-pertuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Tight Glycemic Control and Insulin Administration During Parenteral Nutrition
Status: COMPLETED
Conditions: Critical Ill Patient Undergone Parenteral Nutrition
Interventions: DIETARY_SUPPLEMENT: Insulin separated|DIETARY_SUPPLEMENT: Insulin added to parenteral nutrition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Donafenib Combined With TACE as Adjuvant Therapy of Patients With Hepatocellular Carcinoma
Status: NOT_YET_RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Donafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lacticaseibacillus Rhamnosus GG Pili Study
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Probiotic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Integration of Remote Monitoring in the Management of Chronic Immunosuppressive Therapy
Status: RECRUITING
Conditions: Rheumatoid Arthritis|Psoriatic Arthritis|Systemic Lupus Erythematosus|Systemic Sclerosis|Spondyloarthritis, Axial|Ankylosing Spondylitis
Interventions: OTHER: Remote Monitoring|OTHER: On site monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Caffeine Ingestion to Counter the Exercise-mediated Fall in Glycaemia in Type 1 Diabetes
Status: COMPLETED
Conditions: Caffeine and Carbohydrate|Carbohydrate Only|Placebo
Interventions: DIETARY_SUPPLEMENT: Caffeine and glucose|DIETARY_SUPPLEMENT: Glucose alone|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Magnesium Sulfate and Bupivacaine for Rehabilitation After Distal Radius Fractures
Status: COMPLETED
Conditions: Radius Fracture
Interventions: DRUG: Magnesium Sulfate|DRUG: Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: RECAB-ASA; Treatment of Recurrent Abortion With Aspirin
Status: COMPLETED
Conditions: Abortion, Habitual
Interventions: DRUG: Aspirin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation to Assess the Safety and Efficacy of GentleMax Pro™/GentleMax Pro Plus™
Status: ACTIVE_NOT_RECRUITING
Conditions: Unwanted Fine Facial Hair
Interventions: DEVICE: GentleMax Pro Plus 755nm and 1064nm laser system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Safety, Immunogenicity and Efficacy of R21/Matrix-M1 Malaria Vaccine in Healthy WOCBP in Mali
Status: NOT_YET_RECRUITING
Conditions: Healthy Women of Child Bearing Potential
Interventions: BIOLOGICAL: R21/Matrix-M1|BIOLOGICAL: Saline and R21/Matrix-M1|OTHER: Sterile isotonic (0.9%) normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The PK/PD Study of SHR7280 Tablets in Healthy Subjects.
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: SHR7280|DRUG: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Regenerative Potential of Advanced Platelet Rich Fibrin and Bioactive Glass (Perioglas®).
Status: COMPLETED
Conditions: Chronic Periodontitis|Bone Loss|Intrabony Periodontal Defect
Interventions: PROCEDURE: open flap debridement and filled with A-PRF ( Advanced platelet rich fibrin)|PROCEDURE: open flap debridement and filled with Bioactive glass (Perioglas®)|DRUG: open flap debridement and filled Bioactive glass (Perioglas®) and A-PRF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Peter Hess® Sound Massage for Reducing Anxiety and Pain in Cardiac Surgery
Status: UNKNOWN
Conditions: Pain|Pain, Postoperative|Pain, Chest|Anxiety|Anxiety Postoperative|Thoracic Surgery
Interventions: OTHER: Peter Hess® sound massage|OTHER: Music relaxation Music Care®|OTHER: Questionnaires
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: OTHER
Clinical trial: Gut Derived Hormones, Body Composition and Metabolism in Prader-Willi Syndrome
Status: COMPLETED
Conditions: Prader-Willi Syndrome
Interventions: DRUG: Exenatide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Lapaquistat Acetate Coadministered With Atorvastatin in Subjects With Hypercholesterolemia
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DRUG: Lapaquistat acetate and atorvastatin|DRUG: Atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Low Birthweight and Preterm Infant Feeding Trial and Supportive Care Package: Implementation Research
Status: RECRUITING
Conditions: Low Birthweight|Preterm Birth
Interventions: OTHER: Facility-based feeding support package plus (FB-FSP+)|OTHER: Transition-to-home feeding support package plus (TTH-FSP+)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Safety and Efficacy Study of A Viscoelastic-free Method for Implantable Collamer Lens (ICL) Implantation
Status: RECRUITING
Conditions: Myopia
Interventions: DEVICE: viscoelastic-free implantation system|DEVICE: standard viscoelastic-assisted Implantation system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Pharmacokinetics of AZD4831 When Administered Alone and in Combination With Itraconazole
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: AZD4831|DRUG: Itraconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of GHRH Therapy on Myocardial Structure and Function in Congestive Heart Failure
Status: COMPLETED
Conditions: Congestive Heart Failure
Interventions: DRUG: Growth hormone releasing hormone/ placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Nab® -Paclitaxel (Abraxane®) Plus Gemcitabine in Subjects With Locally Advanced Pancreatic Cancer (LAPC)
Status: COMPLETED
Conditions: Pancreatic Neoplasms
Interventions: DRUG: nab-Paclitaxel|DRUG: Gemcitabine|DRUG: Chemoradiation|DRUG: Capecitabine|PROCEDURE: Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long-term Follow-up of Subjects With Transfusion-Dependent β-Thalassemia (TDT) Treated With Ex Vivo Gene Therapy
Status: ACTIVE_NOT_RECRUITING
Conditions: Transfusion-dependent Beta-Thalassemia
Interventions: OTHER: Safety and efficacy assessments
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety of Plitidepsin in Patients With Advanced Unresectable or Metastatic, Relapsed/Refractory, Dedifferentiated Liposarcoma (DLPS): an Exploratory Phase II Multicenter Trial
Status: TERMINATED
Conditions: Adult Patients With Unresectable Locally Advanced or Metastatic, Relapsed/Refractory Dedifferentiated Liposarcoma
Interventions: DRUG: plitidepsin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Project for Reproductive Equity Through Volunteers and Entrepreneurship, Networks and Technology
Status: NOT_YET_RECRUITING
Conditions: Contraception|Pregnancy Related|Reproductive Behavior
Interventions: BEHAVIORAL: Education|BEHAVIORAL: Personal Support|BEHAVIORAL: Access to contraception
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Efficacy Study of Helicobacter Pylori Eradication in Patients Undergoing Subtotal Gastrectomy for Gastric Cancer
Status: COMPLETED
Conditions: Gastric Cancer
Interventions: DRUG: Helicobacter pylori eradication|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Zeushield Cytotoxic T Lymphocytes (Z-CTLs) for Relapsed or Refractory Non Small Cell Lung Cancer (NSCLC)
Status: UNKNOWN
Conditions: Non-small Cell Lung Cancer
Interventions: BIOLOGICAL: Zeushield Cytotoxic T Lymphocytes
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects Of Acute Supplementation Of Citrus Aurantium L. On The Recovery Of Autonomic And Cardiovascular Activity After A Sub-Maximum Aerobic Exercise Session In Healthy Individuals
Status: UNKNOWN
Conditions: To Evaluate the Effect of Supplementation of Citrus Aurantium in Active Individuals
Interventions: DIETARY_SUPPLEMENT: Citrus aurantium L.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of K-Y Jelly in Prevention of Postoperative Sore Throat After Nasal Surgery
Status: UNKNOWN
Conditions: Postoperative Sore Throat
Interventions: DRUG: K-Y Jelly, Topical Gel soaked packs|OTHER: Water soaked packs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Phase I/II Trial of S64315 Plus Azacitidine in Acute Myeloid Leukaemia
Status: COMPLETED
Conditions: Acute Myeloid Leukaemia
Interventions: DRUG: S 64315 (also referred as MIK665) and azacitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Immunotherapy With Rituximab and Interleukin-2 in Patients With Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: High Risk Non-Hodgkin's Lymphoma
Interventions: BIOLOGICAL: Rituximab|BIOLOGICAL: Interleukin-2
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Metformin and Transient Hyperglycemia
Status: TERMINATED
Conditions: Acute Lymphoblastic Leukemia|Hyperglycemia|Insulin Resistance|Diabetes Mellitus
Interventions: DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Minimally Invasive Pancreatic Enucleation With Main Pancreatic Duct Repair or Reconstruction
Status: NOT_YET_RECRUITING
Conditions: Pancreatic Tumor, Benign|Pancreatic Neuroendocrine Tumor|Solid Pseudopapillary Tumor of the Pancreas
Interventions: PROCEDURE: MPD Repair or Reconstruction
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The University of Alberta Negative Pressure Ventilation Ex-Vivo Lung Perfusion (NPV-EVLP) Trial
Status: COMPLETED
Conditions: Ex-Vivo Lung Transplantation
Interventions: DEVICE: NPV-EVLP
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Low-Density Lipoprotein (LDL) Apheresis Using H.E.L.P. Therapy
Status: COMPLETED
Conditions: Familial Hypercholesterolemia
Interventions: DEVICE: HELP Secura (apheresis treatment)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Investigating the Impact Burden of Nocturia Using the Nocturia Impact Diary
Status: COMPLETED
Conditions: Nocturia
Interventions: DRUG: Desmopressin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Ranolazine on Myocardial Ischemia Detected by High-Field 3T Cardiovascular Magnetic Resonance (CMR) Imaging and P-31 Spectroscopy
Status: UNKNOWN
Conditions: Angina|Heart Disease
Interventions: DRUG: Ranolazine
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Use of Topical Olive Oil Cream for Prophylaxis Against Acute Radiodermatitis in Breast Cancer Patients
Status: RECRUITING
Conditions: Radiodermatitis; Acute
Interventions: DRUG: Olive oil cream|DRUG: Betamethasone Valerate Cream|OTHER: Base Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Study to Assess if ABP798 is Safe & Effective in Treating Non Hodgkin Lymphoma Compared to Rituximab
Status: COMPLETED
Conditions: Lymphoma, Non-Hodgkin
Interventions: BIOLOGICAL: ABP 798|BIOLOGICAL: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: TIPOPS (Telemedicine vs In Person Oncology Patient Surveillance)
Status: COMPLETED
Conditions: Breast Cancer|Prostate Cancer|Patient Engagement|Patient Preference|Patient Satisfaction
Interventions: BEHAVIORAL: FOLLOW UP VISIT-TELEMEDICINE|BEHAVIORAL: FOLLOW UP VISIT-FACE TO FACE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Evaluation of Ocoxin®-Viusid® in Metastatic Colorectal Adenocarcinoma
Status: COMPLETED
Conditions: Colorectal Neoplasm|Intestinal Neoplasms|Gastrointestinal Neoplasms|Digestive System Neoplasm|Rectal Diseases|Colonic Diseases|Intestinal Disease|Gastrointestinal Disease|Digestive System Disease
Interventions: DIETARY_SUPPLEMENT: Ocoxin-Viusid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of the Proximal Contact Quality in Posterior Complex Carious Cavities Restored With Bulk Fill Ormocer and Resin Composite Using a Precontoured Circumferential Matrix System Versus Pre Contoured Sectional Matrix System
Status: NOT_YET_RECRUITING
Conditions: Posterior Complex Carious Proximal Cavities
Interventions: OTHER: Bulk-fill ormocer (Admira fusion x-tra, Voco, Cuxhaven, Germany) with Precontoured circumferential matrix system (Palodent 360, Dentsply Caulk, Millford DE, USA)|OTHER: Bulk-fill ormocer (Admira fusion x-tra, Voco, Cuxhaven, Germany) with Precontoured sectional matrix systym (Saddle matrix, TORVM, Moscow, Russia)|OTHER: Bulk-fill resin composite (X-tra fill, Voco, Cuxhaven, Germany) with Precontoured circumferential matrix system (Palodent 360, Dentsply Caulk, Millford DE, USA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Pneumococcal Conjugate Vaccination in HIV in Comparison to Polysaccharide Vaccine Boosting
Status: COMPLETED
Conditions: HIV Infections|Streptococcus Pneumoniae
Interventions: BIOLOGICAL: pneumococcal conjugate vaccine|BIOLOGICAL: pneumococcal polysaccharide vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: the Effectiveness of Lactoferrin in Treatment of Iron Deficiency Anemia in Children With Chronic Tonsillitis
Status: UNKNOWN
Conditions: Iron-deficiency
Interventions: DRUG: Lactoferrin|DRUG: Ferric Hydroxide Polymaltose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phenylalanine and Its Impact on Cognition
Status: COMPLETED
Conditions: Phenylketonuria
Interventions: DIETARY_SUPPLEMENT: Phenylalanine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Broad Spectrum HPV (Human Papillomavirus) Vaccine Study in 16-to 26-Year-Old Women (V503-001)
Status: COMPLETED
Conditions: Cervical Cancer|Vulvar Cancer|Vaginal Cancer|Genital Warts|Human Papillomavirus Infection
Interventions: BIOLOGICAL: Comparator: GARDASIL|BIOLOGICAL: Experimental: V503
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Oral Supplementation With Selenium in Patients With Mild Thyroid Orbitopathy
Status: COMPLETED
Conditions: Thyroid Orbitopathy
Interventions: DIETARY_SUPPLEMENT: Selenium|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Parallel Study Evaluating the Effect of A-F Betafood® on Gallbladder and Liver Function.
Status: COMPLETED
Conditions: Gallbladder
Interventions: DIETARY_SUPPLEMENT: A-F Betafood|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate Efficacy, Safety, Tolerability and Exposure After a Repeat-dose of Sepofarsen (QR-110) in LCA10 (ILLUMINATE)
Status: ACTIVE_NOT_RECRUITING
Conditions: Leber Congenital Amaurosis 10|Blindness|Leber Congenital Amaurosis|Vision Disorders|Sensation Disorders|Neurologic Manifestations|Eye Diseases|Eye Diseases, Hereditary|Eye Disorders Congenital|Retinal Disease
Interventions: DRUG: sepofarsen|OTHER: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Brown Seaweed Extract on Glycemic Control and Body Weight
Status: COMPLETED
Conditions: PreDiabetes|Insulin Resistance
Interventions: DIETARY_SUPPLEMENT: InSea2|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Reduction of Bacterial Resistance With Inhaled Antibiotics in the Intensive Care Unit
Status: COMPLETED
Conditions: Respiratory Infection|Bacterial Resistance|Respiratory Failure
Interventions: DRUG: vancomycin or gentamicin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Arthroscopic Partial Meniscectomy Versus Exercise Therapy for Meniscal Injuries in Older Patients, a 5 Year Follow up.
Status: COMPLETED
Conditions: Meniscus Tear, Tibial|Osteoarthritis, Knee
Interventions: PROCEDURE: arthroscopic partial meniscectomy|OTHER: Physical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Eriocitrin Supplementation in Subjects With Intermediate Hyperglycemia
Status: COMPLETED
Conditions: Pre Diabetes
Interventions: DIETARY_SUPPLEMENT: Eriocitrin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: GSK BHR Study (Sont)
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Placebo|DRUG: FP 100mcg|DRUG: FP 500mcg|DRUG: FP 250mcg|DRUG: FSC 100/50mcg|DRUG: FSC 250/50mcg|DRUG: FSC 500/50mcg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, and Pharmacokinetic Study of CORT113176 in Healthy Participants
Status: COMPLETED
Conditions: Healthy Adults
Interventions: DRUG: CORT113176|DRUG: Placebo matching CORT113176
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: NGR-TNF in Treating Patients With Advanced Solid Tumors
Status: COMPLETED
Conditions: Colorectal Cancer|Head and Neck Cancer|Kidney Cancer|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: BIOLOGICAL: CNGRC peptide-TNF alpha conjugate
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Promoting CRC Screening in an Urban Minority Population
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: OTHER: Printed Education Material|OTHER: Academic Detailing|OTHER: Academic Detailing+Telephone Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Operations Enduring Freedom and Iraqi Freedom (OEF/OIF)Veteran Preferences for Automated Physical Activity Interventions
Status: UNKNOWN
Conditions: Physical Activity
Interventions: OTHER: Three home-based diet and exercise programs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Multiple Applications of ExpressGraft-C9T1 Skin Tissue as a Treatment for Diabetic Foot Ulcers
Status: TERMINATED
Conditions: Diabetes|Diabetic Foot Ulcer|Non-healing Wound
Interventions: BIOLOGICAL: ExpressGraft-C9T1 Skin Tissue
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Methadone in Pediatric Anesthesia
Status: COMPLETED
Conditions: Anesthesia
Interventions: DRUG: Methadone 0.1mg/kg|DRUG: Methadone 0.2mg/kg|DRUG: Methadone 0.3mg/kg|DRUG: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Celecoxib Versus Hyoscine Butyl-bromide in Reducing Pain Associated With IUD.
Status: COMPLETED
Conditions: IUD Insertion Pain
Interventions: DRUG: hyoscine butyl bromide|DRUG: Celecoxib 200mg|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION