pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Methylprednisolone Sodium Succinate in Treating Patients With Acute Graft-versus-Host Disease of the Gastrointestinal Tract
Status: WITHDRAWN
Conditions: Acute Graft Versus Host Disease|Intestinal Graft Versus Host Disease
Interventions: DRUG: Budesonide|DRUG: Methylprednisolone Sodium Succinate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Protein Supplementation vs Standard Feeds in Underweight Critically Ill Children: A Dual-Centre Pilot RCT
Status: RECRUITING
Conditions: Critically Ill
Interventions: DIETARY_SUPPLEMENT: Enteral protein supplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Variation of Sodium Dialysate in ICU
Status: RECRUITING
Conditions: Acute Kidney Injury|Renal Replacement Therapy
Interventions: DRUG: Lowering sodium concentration dialysate|DRUG: Highing sodium concentration dialysate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Single Group Study to Evaluate the Effects of a Vaginal Probiotic on Vaginal and Digestive Health
Status: COMPLETED
Conditions: Irritable Bowel Syndrome|Vaginal Health
Interventions: DIETARY_SUPPLEMENT: Vaginal Probiotic
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Seroprevalence of Hepatitis B and Immune Response to Hepatitis B Vaccination in Chinese College Students
Status: COMPLETED
Conditions: Hepatitis B|Immune Response|Seroprevalence
Interventions: BIOLOGICAL: HBV vaccine (Engerix-B, recombinant hepatitis B surface antigen, 20µg/mL/vial, GlaxoSmithKline, Belgium)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: GEKO Venous Thromboembolism Prevention Study
Status: RECRUITING
Conditions: Stroke, Acute|Venous Thromboembolism|Deep Vein Thrombosis|Pulmonary Embolism
Interventions: DEVICE: geko™ device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Maternal Dietary Lipids and Omega 3 Essential Fatty Acids Profile in Pregnant Women at Term and Their Fetuses
Status: COMPLETED
Conditions: Lipid Profile in Pregnancy
Interventions: PROCEDURE: Blood sampling|OTHER: Dietary- Normal western diet
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy of Massage Therapy in the Treatment of Generalized Anxiety Disorder (GAD)
Status: COMPLETED
Conditions: Generalized Anxiety Disorder
Interventions: OTHER: Swedish Massage|OTHER: Light Touch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prevention of Postpartum Hemorrhage With Tranexamic Acid
Status: ACTIVE_NOT_RECRUITING
Conditions: Postpartum Hemorrhage
Interventions: DRUG: Tranexamic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Feasibility Study of Co-administering Combination Antiretroviral Therapy (cART) and R-EPOCH Chemotherapy for the Management of ARL
Status: COMPLETED
Conditions: Lymphoma, AIDS Related|HIV Infections
Interventions: DRUG: R-EPOCH and cART
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of an Ecological Momentary Emotion Regulation Intervention
Status: RECRUITING
Conditions: Depressive Disorder, Major|Persistent Depressive Disorder|Healthy
Interventions: BEHAVIORAL: Valence-Specific Ecological Momentary Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Potential Benefits of Home Based Exercise Programs in the Management of Spastic Cerebral Palsy
Status: UNKNOWN
Conditions: Cerebral Palsy, Spastic, Diplegic
Interventions: OTHER: Routine physical therapy|OTHER: Traditional massage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Evaluation of Anti-interference Ability and Clinical Specificity of HIV Ag +Ab Assay Kit (Sysmex)
Status: NOT_YET_RECRUITING
Conditions: HIV Seropositivity|Cancer|Blood Disease
Interventions: DIAGNOSTIC_TEST: HIV Ag +Ab Assay Kit (Sysmex)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Trial of ZN-A-1041 Enteric Capsules in Patients With HER2-Positive Advanced Solid Tumors
Status: RECRUITING
Conditions: Advanced Solid Tumors|HER2-positive Breast Cancer
Interventions: DRUG: ZN-A-1041 50mg BID|DRUG: ZN-A-1041 100mg BID|DRUG: ZN-A-1041 200mg BID|DRUG: ZN-A-1041 400mg BID|DRUG: ZN-A-1041 600mg BID|DRUG: ZN-A-1041 800mg BID|DRUG: ZN-A-1041 1000mg BID|DRUG: ZN-A-1041 Level 1 +Capecitabine 1000 mg/m2 + Trastuzumab 8 mg/kg iv. First Cycle|DRUG: ZN-A-1041 Level 2 +Capecitabine 1000 mg/m2 + Trastuzumab 8 mg/kg iv. First Cycle|DRUG: ZN-A-1041 MAD +Capecitabine 1000 mg/m2 + Trastuzumab 8 mg/kg iv. First Cycle|DRUG: ZN-A-1041+Capecitabine + Trastuzumab 8 mg/kg iv. First Cycle
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Effectiveness and Safety of Risperidone Versus Placebo in the Treatment of Manic or Mixed Episodes Associated With Bipolar I Disorder
Status: COMPLETED
Conditions: Bipolar Disorder|Manic Episode
Interventions: DRUG: Risperidone, oral tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Prophylaxis Against Tuberculosis (TB) in Patients With Human Immunodeficiency Virus (HIV) Infection and Confirmed Latent Tuberculous Infection
Status: COMPLETED
Conditions: HIV Infections|Tuberculosis
Interventions: DRUG: Isoniazid|DRUG: Pyrazinamide|DRUG: Pyridoxine hydrochloride|DRUG: Rifampin
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: Tab Block and Patient Controlled Analgesia in CS
Status: COMPLETED
Conditions: Analgesia
Interventions: DRUG: tab block|DRUG: PCA|DRUG: women who will not receive tab block or PCA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Uroial Plus in the Management of Infections and Urinary Symptoms Associated With Ureteral Stents
Status: NOT_YET_RECRUITING
Conditions: Ureteral Stent-Related Symptom|Urinary Tract Infections
Interventions: OTHER: UroialTM Plus|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of Lasmiditan on the Heart in Healthy Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Lasmiditan|DRUG: Lasmiditan|DRUG: Placebo|DRUG: Moxifloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of IMOVAX POLIO® Subcutaneous as a Booster Vaccine in Pre-school Age Children in Japan
Status: COMPLETED
Conditions: Poliomyelitis|Polio
Interventions: BIOLOGICAL: IMOVAX POLIO®: Inactive Poliovirus Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of Fluvastatin in Children With Heterozygous Familial Hypercholesterolemia
Status: COMPLETED
Conditions: Heterozygous Familial Hypercholesterolemia|Mixed Dyslipidemia
Interventions: DRUG: Fluvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: pBFS-guided High-dose TMS Over DMPFC for Treatment-resistant Major Depressive Disorder
Status: RECRUITING
Conditions: Depression|Major Depressive Disorder|Severe Depression
Interventions: DEVICE: active TMS|DEVICE: sham TMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Efficacy and Safety of Omacor (Omega-3-acid Ethyl Esters) as Add-on Therapy in Hypertriglyceridemic Subjects Treated With Antara (Fenofibrate) Followed by an 8-week Extension
Status: COMPLETED
Conditions: Hypertriglyceridemia
Interventions: DRUG: Antara (fenofibrate) + Lovaza|DRUG: Antara (fenofibrate)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Role of Ginkgo Biloba Extract in IUGR
Status: COMPLETED
Conditions: Intrauterine Growth Restriction (IUGR)
Interventions: DRUG: Ginkgo Biloba Extract|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase III Study of RAD001 Adjuvant Therapy in Poor Risk Patients With Diffuse Large B-Cell Lymphoma (DLBCL) of RAD001 Versus Matching Placebo After Patients Have Achieved Complete Response With First-line Rituximab-chemotherapy
Status: COMPLETED
Conditions: Diffuse Large B-cell Lymphoma
Interventions: DRUG: Everolimus|DRUG: Everolimus Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Leveraging Pharmacogenomics in Asthma for Predication, Mechanism and Endotyping
Status: RECRUITING
Conditions: Moderate to Severe Asthma
Interventions: BIOLOGICAL: Dupilumab|BIOLOGICAL: Benralizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Melatonin in Untreated Obstructive Sleep Apnea
Status: TERMINATED
Conditions: Obstructive Sleep Apnea
Interventions: DIETARY_SUPPLEMENT: Melatonin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Evaluate Safety and Tolerability of IV or SC Dose of MEDI-545 in Patients With Systemic Lupus Erythematosus.
Status: COMPLETED
Conditions: Systemic Lupus Erythematosus
Interventions: DRUG: MEDI-545|DRUG: MEDI-545|DRUG: MEDI-545|DRUG: MEDI-545|DRUG: MEDI-545|DRUG: MEDI-545 600
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PRone positioN in Patients With spontanEous ventiLation and Acute Hypoxemic respIratory FailurE
Status: SUSPENDED
Conditions: Respiratory Failure With Hypoxia|Respiratory Failure Without Hypercapnia
Interventions: OTHER: Prone Position
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Safety and Immunogenicity of Haemophilus Influenzae Type b Vaccine in Different Injection Site
Status: COMPLETED
Conditions: Healthy
Interventions: BIOLOGICAL: Inoculation in upper arm deltoid|BIOLOGICAL: Inoculation in vastus lateralis muscle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Observational Trial of Cardiotoxicity in Patients Undergoing Chemotherapy.
Status: UNKNOWN
Conditions: Cardiotoxicity|Heart Failure|Dilated Cardiomyopathy
Interventions: DIAGNOSTIC_TEST: Echocardiography with speckle tracking analysis.|DIAGNOSTIC_TEST: 48-hour ECG monitoring.|DIAGNOSTIC_TEST: Blood samples analysis.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Intraoperative Angiography Using ICG in Rectal Cancer Patients to Prevent Anastamotic Leak After Laparoscopic Anterior Resection of the Rectum
Status: RECRUITING
Conditions: Rectal Cancer
Interventions: DRUG: Verdye Green
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Importance in Type 1 Diabetes Patients of an Optimized Control of Post-Prandial Glycaemia on Oxidant Stress Prevention
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: OTHER: Therapeutic and preventive strategies|OTHER: Therapeutic and preventive strategies
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Clinical Trial Assessing Once Daily Raltegravir Administration (800 mg QD) in HIV-1-Infected Patients Receiving Unboosted Atazanavir (400 mg QD)- Based Antiretroviral Therapy
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Addition of raltegravir 800 mg QD to HAART
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Development and Evaluation of TRIVEL Smart Bike Training Prescription Programs.
Status: RECRUITING
Conditions: Aging|Mobility Limitation
Interventions: DEVICE: Intelligent stationary bike|DEVICE: Conventional stationary bilke
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Therapeutic Effect of Two Muscle Strengthening Programs in Patients With Patellofemoral Pain Syndrome
Status: COMPLETED
Conditions: Patellofemoral Pain Syndrome
Interventions: OTHER: Strengthening program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Dexmedetomidine Versus Morphine as an Adjunct to Bupivacaine in Caudal Anesthesia.
Status: COMPLETED
Conditions: Anesthesia, Local
Interventions: DRUG: Dexmedetomidine|DRUG: Morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Dalantercept and Axitinib in Patients With Advanced Renal Cell Carcinoma
Status: TERMINATED
Conditions: Advanced Renal Cell Carcinoma
Interventions: DRUG: Dalantercept and axitinib|DRUG: Placebo and axitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multicenter Phase 2 Trial Evaluating Cisplatin-Gemcitabine With Concomitant Thoracic Radiotherapy for Treatment of Inoperable Stage III Non Small Cell Lung Cancer
Status: COMPLETED
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: gemcitabine|DRUG: cisplatin|RADIATION: radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Twelve Week Study of Supervised Mouth Rinse and Flossing
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: Colgate Cavity Protection Toothpaste|OTHER: American Dental Association (ADA) Referenced Toothbrush|OTHER: 5% Hydroalcohol Mouth Rinse|OTHER: REACH Dental Floss|OTHER: Alcohol-containing Essential Oil (AEO) Mouth Rinse (Listerine Cool Mint, marketed)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: OTHER
Clinical trial: Interleukin-2 Therapy of Autoimmunity in Diabetes (ITAD)
Status: UNKNOWN
Conditions: Type1 Diabetes
Interventions: DRUG: Aldesleukin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An Open-label Continuation Study Evaluating the Long-term Safety of Extended Release Ropinirole XL (Formerly CR) in Parkinson''s Disease
Status: COMPLETED
Conditions: Parkinson Disease|Parkinson's Disease
Interventions: DRUG: Ropinirole XL (formerly CR)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of C-arm CT in Patients With HCC Undergoing TACE: Optimal Imaging Guidance
Status: COMPLETED
Conditions: Carcinoma, Hepatocellular
Interventions: DEVICE: C-arm CT + DSA as needed|DEVICE: DSA only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparative Effect of Cylindrical Lenses Verses Spherical Equilient on Contrast Sensitivity
Status: ACTIVE_NOT_RECRUITING
Conditions: Low Vision Aids
Interventions: DIAGNOSTIC_TEST: Contrast sensitivity|OTHER: Refraction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Changes in Cerebral Function in Treatment Naive HIV-1 Infected Subjects Commencing Either Boosted Atazanavir With Truvada or Boosted Darunavir With Maraviroc and Kivexa
Status: COMPLETED
Conditions: HIV|Impaired Cognition
Interventions: DRUG: standard care|DRUG: novel treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of 5 mg Sublingual Zolpidem vs 10mg Oral Zolpidem in the Induction and Maintenance of Sleep in Patients With Primary Insomnia
Status: COMPLETED
Conditions: Primary Insomnia
Interventions: DRUG: Zolpidem Hemitartrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: S.T.O.P.® Technology Contact Lenses Versus Dual-focus Contact Lenses for Slowing Down Myopia Progression in Children
Status: RECRUITING
Conditions: Myopia
Interventions: DEVICE: S.T.O.P® F2|DEVICE: S.T.O.P® DT|DEVICE: MiSight®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Integration of Hypertension Management Into HIV Care in Nigeria
Status: ACTIVE_NOT_RECRUITING
Conditions: Human Immunodeficiency Virus|Hypertension
Interventions: BEHAVIORAL: Task-shifting strategy for HTN control (TASSH) protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Randomized Controlled Clinical Trial on the Use of Saline Nasal Irrigations to Eradicate Localized Nasal Infection by SARS-CoV-2
Status: COMPLETED
Conditions: Symptoms and Signs
Interventions: DEVICE: Nasal lavages with Tonimer Panthexyl®
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cabozantinib in Advanced Pancreatic Neuroendocrine and Carcinoid Tumors
Status: COMPLETED
Conditions: Carcinoid Tumor|Pancreatic Neuroendocrine Tumor
Interventions: DRUG: Cabozantinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Mucosal Bolivian Leishmaniasis
Status: RECRUITING
Conditions: Mucosal Leishmaniasis
Interventions: DRUG: Group 1: Miltefosine|DRUG: Group 2: Pentavalent Antimony|DRUG: Group 3: Liposomal amphotericin B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Heparin Anticoagulation to Improve Outcomes in Septic Shock: The HALO Pilot
Status: COMPLETED
Conditions: Septic Shock
Interventions: DRUG: Unfractionated heparin|DRUG: Dalteparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Riluzole and Whole-Brain Radiation Therapy in Treating Patients With Brain Metastases
Status: TERMINATED
Conditions: Metastatic Cancer|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: riluzole|RADIATION: whole-brain radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Autologous Hematopoietic Cell Transplantation for Core-binding Factor Acute Myeloid Leukemia
Status: UNKNOWN
Conditions: Leukemia, Myeloid
Interventions: PROCEDURE: autologous hematopoietic cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Organizational Skills Interventions for Children With Attention Deficit Hyperactivity Disorder (ADHD)
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: BEHAVIORAL: Homework, Organization, and Planning Skills (HOPS) Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hypofractionated vs. Conventionally Fractionated Concurrent CRT for LD-SCLC
Status: UNKNOWN
Conditions: Carcinoma, Small Cell|Lung Neoplasms
Interventions: RADIATION: hypofractionated concurrent chemoradiotherapy|RADIATION: conventionally fractionated concurrent chemoradiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fecal Microbiota Transplant by Oral Capsules With Lactobacilli for Recurrent Clostridium Difficile Infection
Status: UNKNOWN
Conditions: Clostridium Difficile Infection
Interventions: BIOLOGICAL: FMT-c|BIOLOGICAL: FMT-c Lactobacillus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Placebo Controlled Study in Subjects With Relapsing Forms of MS to Evaluate the Safety, Tolerability and Effects of CDP323
Status: TERMINATED
Conditions: Multiple Sclerosis
Interventions: DRUG: CDP323|DRUG: placebo|DRUG: CDP323
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Nobori And Uncoated Stent In Coronary Attack
Status: TERMINATED
Conditions: Acute Myocardial Infarction
Interventions: DEVICE: Biolimus A9 eluting stents|PROCEDURE: uncoated stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of High-intensity Aerobic Training in Patients With Metabolic Syndrome
Status: UNKNOWN
Conditions: Metabolic Syndrome X|Exercise|Physical Activity
Interventions: BEHAVIORAL: Aerobic interval training|BEHAVIORAL: Continuous moderate-intensity exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Jail-Based Impact of Crime Intervention
Status: UNKNOWN
Conditions: Substance Abuse|HIV Risk|Criminogenic Thinking|Shame|Guilt|Empathy
Interventions: BEHAVIORAL: MI plus IOC group intervention|BEHAVIORAL: Motivational Interview only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dry Needling Versus Conservative Treatment in the Rectus Femoris Muscle Approach.
Status: COMPLETED
Conditions: Dry Needling|Stretch|Rectus Femoris Muscle
Interventions: OTHER: Deep Dry Needling|OTHER: Superficial Dry Needling|OTHER: passive stretching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Effect of Patient Education (Talking Health Together) in Improving Doctor-patient Communication
Status: COMPLETED
Conditions: Doctor-patient Communication Improvement
Interventions: BEHAVIORAL: THT PACE Training|BEHAVIORAL: THT PACE Training|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: MoLiMoR - A Study With FOLFIRI-based First-line Therapy With or Without Intermittent Cetuximab
Status: ACTIVE_NOT_RECRUITING
Conditions: Adenocarcinoma of the Colon|Adenocarcinoma of the Rectum
Interventions: DRUG: Cetuximab|OTHER: FOLFIRI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of the Financial Inclusion Improves Sanitation and Health
Status: RECRUITING
Conditions: Health Knowledge, Attitudes, Practice
Interventions: BEHAVIORAL: Financial Inclusion Improves Sanitation and Health
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Eribulin and Radiation Therapy in Treating Patients With Retroperitoneal Liposarcoma That Can Be Removed by Surgery
Status: ACTIVE_NOT_RECRUITING
Conditions: Liposarcoma|Malignant Abdominal Neoplasm|Malignant Retroperitoneal Neoplasm|Malignant Scrotal Neoplasm|Malignant Solid Neoplasm|Malignant Spermatic Cord Neoplasm
Interventions: DRUG: Eribulin Mesylate|RADIATION: Intensity-Modulated Radiation Therapy|OTHER: Laboratory Biomarker Analysis|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration|PROCEDURE: Therapeutic Conventional Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Inflated Versus Non-inflated Endotracheal Tube on Sore Throat
Status: RECRUITING
Conditions: Postoperative Sore Throat
Interventions: OTHER: Pre-inflated endotracheal tube|OTHER: Non-inflated endotracheal tube
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Neurofeedback Intervention for Reading Deficits in Subacute Stroke
Status: RECRUITING
Conditions: Stroke|Dyslexia, Acquired
Interventions: BEHAVIORAL: Motor Imagery and Real-Time fMRI Neurofeedback|BEHAVIORAL: Motor Imagery and Sham fMRI Neurofeedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Use of Airtime Timing to Improve Interactive Voice Response Surveys in Bangladesh and Uganda
Status: COMPLETED
Conditions: Surveys and Questionnaires|Noncommunicable Diseases
Interventions: OTHER: Pre-survey incentive|OTHER: Post-survey incentive
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: The Effect of Panax Notoginseng Powders on Rheumatic Pain
Status: UNKNOWN
Conditions: Rheumatic Pain
Interventions: DIETARY_SUPPLEMENT: Panax Notoginseng Powder 1g|DIETARY_SUPPLEMENT: Panax Notoginseng Powder 5g|DIETARY_SUPPLEMENT: Panax Notoginseng Powder 10g|DIETARY_SUPPLEMENT: Panax Notoginseng Powder 15g|DRUG: Celecoxib Capsule 400 mg daily
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of T-817MA in Patients With Mild to Moderate Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: T-817MA|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety of Meningococcal ACYW135 Polysaccharide Conjugate Vaccine in Volunteers Aged From 3 to 35 Months
Status: COMPLETED
Conditions: Meningitis, Meningococcal
Interventions: BIOLOGICAL: Meningococcal ACYW135 Polysaccharide Conjugate Vaccine|BIOLOGICAL: Meningococcal ACYW135 Polysaccharide Conjugate Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Chronic Pain After Groin Hernia Surgery in Women
Status: COMPLETED
Conditions: Hernia, Inguinal|Hernia, Femoral
Interventions: PROCEDURE: Totally ExtraPeritoneal (TEP) repair|PROCEDURE: TransAbdominal PrePeritoneal (TAPP) repair|PROCEDURE: Open anterior mesh repair (OAM)|PROCEDURE: Combined Anterior and Posterior technique (CAP)|PROCEDURE: Open PrePeritoneal Mesh technique (OPPM)|PROCEDURE: Sutured Repair
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Selective Versus Stepwise Removal of Deep Carious Lesions in Permanent Teeth Using Different Medicaments
Status: COMPLETED
Conditions: Caries Arrested
Interventions: PROCEDURE: partial caries removal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: HORIZANT (Gabapentin Enacarbil Extended-Release Tablets) for the Treatment of Alcohol Use Disorder
Status: COMPLETED
Conditions: Alcohol Use Disorder
Interventions: DRUG: gabapentin enacarbil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial Investigating the Pharmacodynamic Properties of NN5401 in Subjects With Type 1 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 1
Interventions: DRUG: insulin degludec|DRUG: insulin degludec/insulin aspart
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of Combined Hepatitis A and Hepatitis B Vaccine to Protect Against Hepatitis B in Hemodialysis Patients
Status: COMPLETED
Conditions: Hepatitis B
Interventions: BIOLOGICAL: Engerix-B and Twinrix
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: PREVENTION
Clinical trial: Safety and Tolerability of Intravenous LFG316 in Wet Age-related Macular Degeneration (AMD).
Status: TERMINATED
Conditions: Neovascular Age-related Macular Degeneration
Interventions: DRUG: Placebo|DRUG: LFG316|DRUG: LFG316
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy & Safety of Dronedarone Versus Amiodarone for the Maintenance of Sinus Rhythm in Patients With Atrial Fibrillation
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DRUG: dronedarone (SR33589)|DRUG: amiodarone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Music Periodicity on Interictal Epileptiform Discharges
Status: COMPLETED
Conditions: Rolandic Epilepsy|Benign Childhood Epilepsy With Centrotemporal Spikes|Epilepsy|Seizures
Interventions: OTHER: Mozart alternating with Beethoven|OTHER: Beethoven alternating with Mozart
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: DPA-714 and FDG PET/MRI in Depression
Status: NOT_YET_RECRUITING
Conditions: Depression
Interventions: RADIATION: PET scan with tracer injection [18F] DPA-714 or [18F]F-FDG
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Low Carbohydrate Diet - Effect on Plasma Lipids and Metabolic Markers
Status: COMPLETED
Conditions: Overweight and Obesity|Type IIb Hyperlipidaemia|Hypercholesterolemia Aggravated
Interventions: OTHER: Low carbohydrate dietary advice|OTHER: Continue usual diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Lung Ultrasound Assessment of Fluid Overload in Haemodialysis Patients
Status: COMPLETED
Conditions: Lung Ultrasound|Hemodialysis Complication
Interventions: OTHER: lung ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Prospective Intervention Study to Improve HRQoL and Exercise Tolerance After Heart Transplantation
Status: UNKNOWN
Conditions: Exercise Capacity|Heart Transplantation
Interventions: BEHAVIORAL: exercise training; psychosocial support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Test the Safety and Effectiveness of MK-0974 (Telcagepant) Co-administered With Ibuprofen or Acetaminophen in Patients With Migraines With or Without Aura (MK-0974-046)
Status: COMPLETED
Conditions: Migraine
Interventions: DRUG: placebo|DRUG: ibuprofen|DRUG: acetominophen|DRUG: telcagepant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cholecalciferol in Treating Patients With Acute Myeloid Leukemia Undergoing Intensive Induction Chemotherapy
Status: TERMINATED
Conditions: Adult Acute Megakaryoblastic Leukemia (M7)|Adult Acute Monoblastic Leukemia (M5a)|Adult Acute Monocytic Leukemia (M5b)|Adult Acute Myeloblastic Leukemia With Maturation (M2)|Adult Acute Myeloblastic Leukemia Without Maturation (M1)|Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities|Adult Acute Myeloid Leukemia With Del(5q)|Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)|Adult Acute Myeloid Leukemia With t(16;16)(p13;q22)|Adult Acute Myeloid Leukemia With t(8;21)(q22;q22)|Adult Acute Myelomonocytic Leukemia (M4)|Adult Erythroleukemia (M6a)|Adult Pure Erythroid Leukemia (M6b)|Untreated Adult Acute Myeloid Leukemia
Interventions: DIETARY_SUPPLEMENT: cholecalciferol|OTHER: pharmacological study|DIETARY_SUPPLEMENT: cholecalciferol|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Image Characteristic and Longitudinal Follow up of 18F-PMPBB3 (APN-1607) PET for Progressive Supranuclear Palsy
Status: UNKNOWN
Conditions: Progressive Supranuclear Palsy
Interventions: DIAGNOSTIC_TEST: 18F-PMPBB3
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study on 30 Outpatients With Chronic Migraine Treated With Well-Being Therapy or With a Control Therapy
Status: RECRUITING
Conditions: Chronic Migraine
Interventions: BEHAVIORAL: Well-Being Therapy|OTHER: Control condition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Exercise Program in Breast Cancer Patients Receiving Neoadjuvant Chemotherapy
Status: COMPLETED
Conditions: Breast Neoplasm|Physical Activity
Interventions: BEHAVIORAL: Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Autologous Tenocyte Implantation in Patients With Chronic Achilles Tendinopathy
Status: COMPLETED
Conditions: Tendinopathy|Achilles Tendon Injury|Achillodynia
Interventions: OTHER: Autologous Tenocyte Implantation|OTHER: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of MUCIPLIQ on the Incidence of Radio-chemotherapy-induced Mucositis in Patients Suffering From Oral Cancer
Status: COMPLETED
Conditions: Oral Mucositis|Carcinoma in Situ of Upper Respiratory Tract
Interventions: DEVICE: MUCIPLIQ|DEVICE: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Simplified Conservative Measures in Managing Morbidly Adherent Placenta in Beni-Suef University
Status: RECRUITING
Conditions: Placenta Accreta
Interventions: PROCEDURE: O, lreay suture|PROCEDURE: modified O, lreay suture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot of Enhanced Child Adult Relationship Enhancement in Pediatric Primary Care
Status: COMPLETED
Conditions: Child Behavior Problem|Parent-Child Relations
Interventions: BEHAVIORAL: PriCARE|BEHAVIORAL: Positive Discipline Module
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lifestyle Intervention Trial in Obese Elderly
Status: COMPLETED
Conditions: Obesity
Interventions: BEHAVIORAL: Diet + Resistance Training|BEHAVIORAL: Diet + Aerobic Training|BEHAVIORAL: Diet + Resistance/Aerobic Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Oral Probiotic Administration in Patients With Chronic Periodontitis
Status: UNKNOWN
Conditions: -Chronic Periodontitis
Interventions: OTHER: Lactobacillus rhamnosus SP1|OTHER: Talc powder|PROCEDURE: Periodontal treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Strategies for Maintenance Therapies in Advanced Non Small Cell Lung Cancer
Status: COMPLETED
Conditions: Advanced Non Small Cell Lung Cancer
Interventions: DRUG: Cisplatin|DRUG: Pemetrexed|DRUG: Cisplatin|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Intraoperative Radiotherapy for Middle and Low Rectal Cancer
Status: UNKNOWN
Conditions: Rectal Cancer
Interventions: RADIATION: Intraoperative radiotherapy by Intrabeam（Zeiss Meditech，Jena，Germany）
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of 3 Weekly Injections of Hyaluronate in Patients With Ankle Osteoarthritis
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DRUG: sodium hyaluronate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic of Tacrolimus in Paediatric Liver Transplant Patients
Status: UNKNOWN
Conditions: Liver Transplantation, Child
Interventions: OTHER: Pharmacokinetic|OTHER: Pharmacogenetic|DRUG: Tacrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of Tarcocimab Tedromer Compared With Sham Treatment in Participants With Moderately Severe to Severe Non-proliferative Diabetic Retinopathy (NPDR)
Status: RECRUITING
Conditions: Non-proliferative Diabetic Retinopathy
Interventions: DRUG: Tarcocimab|OTHER: Sham injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Imatinib 400 mg Once Daily in Combination With Methotrexate in the Treatment of Rheumatoid Arthritis.
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Imatinib|DRUG: Methotrexate|DRUG: Imatinib Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Physical Therapy on Non-structural Medial Elbow Pain
Status: COMPLETED
Conditions: Elbow Injuries and Disorders|Neuritis, Ulnar|Neuritis, Brachial|Neuritis; Nerve Root|Neuritis Median Nerve
Interventions: OTHER: Rehabiltiation using exercise and manual therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Pediatric Patients With Attention Deficit/Hyperactivity Disorder
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: DRUG: LY2216684|DRUG: Methylphenidate|DRUG: Placebo (tablet)|DRUG: Placebo (capsule)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Improving Outcome of Selected Patients With Non-resectable Hepatic Metastases From Colo-rectal Cancer With Liver Transplantation
Status: RECRUITING
Conditions: Liver Metastases|Colorectal Cancer Metastatic|Liver Neoplasm|Neoplasms
Interventions: PROCEDURE: Liver transplant|DRUG: Chemotherapy|DRUG: Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Avastin (Bevacizumab) in Combination With XELOX or FOLFOX-4 in Patients With Metastatic Colorectal Cancer.
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: bevacizumab [Avastin]|DRUG: XELOX|DRUG: bevacizumab [Avastin]|DRUG: FOLFOX-4
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Neck Strength Training on Health-related Quality of Life in Females With Neck Pain
Status: COMPLETED
Conditions: Neck Pain
Interventions: BEHAVIORAL: Neck endurance training|BEHAVIORAL: Stretching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Impact of Steviol Glycosides on Human Gut Microflora Profile and Function
Status: COMPLETED
Conditions: Healthy|Human Gut Microflora
Interventions: OTHER: Sucrose|OTHER: Steviol Glycosides
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: ZN-c3 in Adult Participants With Metastatic Colorectal Cancer
Status: RECRUITING
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: ZN-c3|DRUG: Encorafenib|DRUG: Cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Serum Neurofilament Light (NFL) in Surgery Under General Anaesthesia (GA) Compared to Surgery With Hypno-analgesia (Hyp)
Status: UNKNOWN
Conditions: General Surgery
Interventions: OTHER: General anesthesia|OTHER: Hypno-analgesia
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Sublimated Mare Milk Supplement's Effect on Gut Mucosal Lining After Antibiotics
Status: COMPLETED
Conditions: Acute Bronchitis
Interventions: DIETARY_SUPPLEMENT: Sublimated mare milk supplement|DRUG: Standard antibiotic therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chondrofix Osteochondral Allograft Prospective Study
Status: TERMINATED
Conditions: Articular Cartilage Disorder|Degeneration; Articular Cartilage|Chronic Cartilage Injury|Acute Cartilage Injury|Defect of Articular Cartilage
Interventions: PROCEDURE: Chondrofix Osteochondral Allograft
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Meniscal Extrusion by Dynamic Ultrasonography in Patients With Ostearthritis
Status: RECRUITING
Conditions: Knee Osteoarthritis|Meniscus Disorder
Interventions: DIAGNOSTIC_TEST: Ultrasonographic evaluation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Steroid-Releasing S8 Sinus Implant for Recurrent Nasal Polyps
Status: COMPLETED
Conditions: Chronic Sinusitis|Nasal Polyps
Interventions: DRUG: S8 Sinus Implant|PROCEDURE: Sham procedure|DRUG: Mometasone furoate nasal spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess Menstrual Cramp Pain Associated With Primary Dysmenorrhea
Status: COMPLETED
Conditions: Dysmenorrhea
Interventions: DRUG: Naproxen Sodium, (Aleve, BAY117031)|DRUG: Acetaminophen (Tylenol Extra Strength)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Explore the Efficacy of Multiple Doses of FURESTEM-AD Inj. for Moderate to Severe Chronic Atopic Dermatitis
Status: UNKNOWN
Conditions: Atopic Dermatitis
Interventions: BIOLOGICAL: FURESTEM-AD inj
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Optimal Duration of Dual Antiplatelet Therapy After Drug-eluting Stent Implantation
Status: COMPLETED
Conditions: Coronary Artery Disease|Stent Thrombosis|Myocardial Ischemia
Interventions: DRUG: Aspirin and Clopidogrel|DRUG: Aspirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT