pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Community Health Workers in Pediatric Patients With Newly Diagnosed Type 1 Diabetes
Status: ACTIVE_NOT_RECRUITING
Conditions: Type 1 Diabetes|Diabetes Mellitus|Psychosocial Problem|Compliance, Patient|Health Behavior
Interventions: OTHER: Community Health Worker added to diabetes team
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Surgery Versus Fibrinolytic Therapy for Left-sided Prosthetic Heart Valve Thrombosis
Status: UNKNOWN
Conditions: Left-sided Prosthetic Heart Valve Thrombosis
Interventions: PROCEDURE: Emergency surgery|DRUG: Fibrinolytic therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ventilation Using a Bag Valve Mask With Integrated Internal Handle
Status: COMPLETED
Conditions: Apnea
Interventions: DEVICE: Modified Ambu Spur II bag valve mask|DEVICE: Conventional Ambu Spur II bag valve mask
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Three Modes of Ventilation During Robot-assisted Hysterectomy in Trendelenburg Position
Status: UNKNOWN
Conditions: Anesthesia
Interventions: DEVICE: Group VCV|DEVICE: Group PCV|DEVICE: Group PCV-VG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: DDEP for Lifestyle Modification in Chronic Kidney Disease: A Randomized Feasibility Trial
Status: NOT_YET_RECRUITING
Conditions: Chronic Kidney Diseases
Interventions: BEHAVIORAL: Digital Dyadic Empowerment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Trial of Proton Pump Inhibitor With Prokinetics or Placebo in Patients With Laryngopharyngeal Reflux Disease
Status: UNKNOWN
Conditions: Laryngopharyngeal Reflux Disease
Interventions: DRUG: Motilitone|DRUG: Pantoprazole|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Long-term Study in Patients With Chronic Kidney Disease and Hyperphosphatemia on Hemodialysis
Status: COMPLETED
Conditions: Chronic Kidney Disease|Renal Dialysis|Renal Insufficiency|Hyperphosphatemia
Interventions: DRUG: ASP1585
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Real Time Continuous Glucose Monitoring System on the Management of Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DEVICE: Guardian RT|BEHAVIORAL: Education about the self monitoring blood glucose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: To Demonstrate the Relative Bioequivalency Study of Dosage Forms of Clemastine 2.68 mg Tablets
Status: COMPLETED
Conditions: Allergy
Interventions: DRUG: Clemastine Fumarate Tablets, 2.68 mg (Cord Laboratories)|DRUG: Tavist Tablets, 2.68 mg (Sandoz Pharmaceutical Corp.)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety of Ozanimod Exposure During Pregnancy in Women With Multiple Sclerosis and Their Infants
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Sclerosis
Interventions: DRUG: Ozanimod|DRUG: Select DMTs other than ozanimod|DRUG: No DMTs
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phase I/II Open Label Study Evaluating the Safety and Efficacy of Combining STAT3 Inhibition (TTI-101) With Anti-PD-1 Therapy (Pembrolizumab) in Patients With Recurrent or Metastatic (RM) Head and Neck Squamous Cell Carcinoma (HNSCC)
Status: NOT_YET_RECRUITING
Conditions: Head and Neck Squamous Cell Carcinoma
Interventions: DRUG: TTI-101|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Role of Aldosterone on Augmented Exercise Pressor Reflex in Hypertension
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Eplerenone|DRUG: Amlodipine|PROCEDURE: Microneurography|PROCEDURE: Rhythmic handgrip exercise|PROCEDURE: Sustained hand grip|PROCEDURE: Forearm blood flow|PROCEDURE: Arm cycling exercise|PROCEDURE: Cold Pressor test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Osimertinib or Docetaxel-bevacizumab as Third-line Treatment in EGFR T790M Mutated Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Progression Free Survival
Interventions: DRUG: Osimertinib|DRUG: docetaxel, bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Host RNA Expression Profiles and Protein Biomarkers in Neonatal Herpes Simplex Virus Infection
Status: COMPLETED
Conditions: Neonatal Herpes Simplex Infection|Neonatal HSV Infection|Neonatal Infection|Newborn; Infection|Herpes Simplex Virus Infection|Neonatal Sepsis|Neonatal Death|Viral Infection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: An Extension Study of the Efficacy and Safety of Fingolimod (FTY720) in Patients With Relapsing Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DRUG: Fingolimod
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immersive Virtual Reality for Visuo-motor Integration Skill Assessment
Status: TERMINATED
Conditions: Cerebral Palsy|Hemiplegia
Interventions: DEVICE: Immersive virtual reality visuo-motor skill assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Evaluation of the Blood Levels of the Drug (Lixisenatide), the Plasma Glucose Levels and Safety in Paediatric and Adult Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Lixisenatide (AVE0010)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective Randomized Trial About THD Versus Ligasure Hemorrhoidectomy for Grade III and IV Hemorrhoids
Status: COMPLETED
Conditions: Hemorrhoids
Interventions: DEVICE: Transanal hemorrhoidal dearterialization + mucopexy (THD).|PROCEDURE: Ligasure™ hemorrhoidectomy|DEVICE: THD anoscope and doppler|DEVICE: Ligasure Vessel Sealing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oxytocin and Reward Processing in Women
Status: RECRUITING
Conditions: Menstrual Cycle|Hormonal Contraception
Interventions: DRUG: Intranasal oxytocin administration|DRUG: Intranasal placebo administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Impact of Low Dose Fluoroscopy in Ureteroscopy
Status: COMPLETED
Conditions: Ureteral Stone
Interventions: RADIATION: 1/4 fluoroscopy dose|RADIATION: Full-dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: IFM2009-02-Pomalidomide and Dexamethasone Phase 2 Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Pomalidomide|DRUG: Pomalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Functional Magnetic Resonance Imaging in Patients With Obstructive Sleep Apnea Syndrome
Status: RECRUITING
Conditions: Obstructive Sleep Apnea Syndrome
Interventions: DIAGNOSTIC_TEST: functional magnetic resonance imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: nCLE For Diagnosis Of Peripheral Lung Nodules By Robotic Navigational Bronchoscopy
Status: ACTIVE_NOT_RECRUITING
Conditions: Diagnosis of Peripheral Lung Nodules
Interventions: DEVICE: Images acquired by needle-based Confocal Laser Endomicroscopy (nCLE)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Soft Coagulation for the Prevention of Adenoma Recurrence
Status: COMPLETED
Conditions: Colonic Adenomas
Interventions: OTHER: Snare Tip Soft Coagulation|OTHER: No Snare Tip Soft Coagulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Peri-implant Conditions of Orthodontic Mini Implants
Status: COMPLETED
Conditions: Dental Implantation|Peri-implant Mucositis|Gingival Inflammation|Implant Stability|Orthodontics
Interventions: OTHER: Peri-implant Condition Evaluation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: To Evaluate the Beneficial Effect of Probiotics on NAFLD Patients and the Role of Gut Microbiota Modulation
Status: COMPLETED
Conditions: Non-Alcoholic Fatty Liver Disease
Interventions: OTHER: Placebo|DIETARY_SUPPLEMENT: Probiotics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Adding Instrument Assisted Soft Tissue Mobilization to Core Stability Training in Chronic Mechanical Neck Pain
Status: COMPLETED
Conditions: Neck Pain
Interventions: OTHER: Conventional physiotherapy|OTHER: Core stability|DEVICE: Instrument assisted soft tissue mobilization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Esomeprazole Magnesium Dihydrate 40 mg Tablets Relative to Nexium 40 mg Tablets Under Fed Condition
Status: NOT_YET_RECRUITING
Conditions: Healthy Subjects
Interventions: DRUG: Esomeprazole magnesium dihydrate-Test product|DRUG: Esomeprazole magnesium dihydrate-Reference product
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Platelet Rich Plasma for Patients With Recurrent Implantation Failure
Status: COMPLETED
Conditions: Infertility
Interventions: COMBINATION_PRODUCT: Platelet rich plasma|COMBINATION_PRODUCT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Radium-223 Combined With Dexamethasone as First-line Therapy in Patients With M+CRPC
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Prostate Cancer
Interventions: DRUG: Dexamethasone plus Radium-223
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Avastin (Bevacizumab) in Combination With Chemotherapy in Patients With Primary Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: bevacizumab [Avastin]|DRUG: docetaxel|DRUG: capecitabine [Xeloda]
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pyrotinib in Combination With Trastuzumab in Treatment-refractory, HER2-positive Metastatic Colorectal Cancar.
Status: UNKNOWN
Conditions: Colorectal Cancer
Interventions: DRUG: Pyrotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose Proportionality Study: Blood Levels of Fluticasone Furoate (FF) and Vilanterol (VI) Following Different Doses of FF/VI Via an Inhaler
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Fluticasone furoate 50 mcg (4 inhalations)|DRUG: Fluticasone furoate 100 mcg (4 inhalations)|DRUG: Fluticasone furoate 200 mcg (4 inhalations)|DRUG: Vilanterol 25 mcg (4 inhalations)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Multi-domain Online Therapeutic Investigation Of Neurocognition (MOTION)
Status: ACTIVE_NOT_RECRUITING
Conditions: Mild Cognitive Impairment|Subjective Memory Decline
Interventions: BEHAVIORAL: Tai Chi|BEHAVIORAL: Preventing Loss of Independence through Exercise (PLIE)|BEHAVIORAL: Health and Wellness Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Insulin Resistance Following ADT for Prostate CA
Status: WITHDRAWN
Conditions: Insulin Resistance|Prostate Cancer
Interventions: DRUG: Pioglitazone 30 Mg Oral Tablet|DRUG: Pioglitazone placebo tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Cranberry Juice on Cardiovascular Risk Factors
Status: COMPLETED
Conditions: Cardiovascular Disease Risk Factors
Interventions: DIETARY_SUPPLEMENT: Cranberry Juice Beverage|DIETARY_SUPPLEMENT: Placebo Beverage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of Baricitinib (LY3009104) in Participants With Severe or Very Severe Alopecia Areata
Status: ACTIVE_NOT_RECRUITING
Conditions: Alopecia Areata
Interventions: DRUG: Baricitinib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Lung Volume Reduction Coils for Emphysema in Alpha-1 Antitrypsin Deficiency
Status: WITHDRAWN
Conditions: Alpha-1-Antitrypsin Deficiency|Chronic Obstructive Lung Disease|Emphysema
Interventions: DEVICE: Lung Volume Reduction Coil (PneumrX Inc.)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the FGM Profiles in Patients of Type 2 Diabetes Treated With Sitagliptin and Acarbose
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: sitagliptin and acarbose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ayurveda Self-Management for Flu Like Symptoms During the Covid-19 Outbreak
Status: COMPLETED
Conditions: Flu Like Symptom|Flu Like Illness
Interventions: OTHER: Individualised Ayurveda
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Behavioral Relaxation Approaches for Insomnia in Lung Cancer Patients
Status: NOT_YET_RECRUITING
Conditions: Insomnia
Interventions: BEHAVIORAL: Assisted Relaxation Therapy|BEHAVIORAL: Modified Assisted Relaxation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Maternal Treatment With ACE-inhibitors and Breastfeeding: a Mono-centric Study on the Exposure Through Breast Milk
Status: COMPLETED
Conditions: Breast Feeding|Hypertension|Heart Failure|Proteinuria
Interventions: PROCEDURE: Venipuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Methoxyflurane and Fentanyl in LBNP
Status: COMPLETED
Conditions: Hypovolemia|Cardiac Output, Low|Analgesia
Interventions: PROCEDURE: Lower body negative pressure (LBNP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of Mometasone Furoate/Formoterol Fumarate (MF/F) Metered Dose Inhaler (MDI) in Adolescents & Adults With Persistent Asthma (P08212)
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Mometasone Furoate/Formoterol Fumarate (MF/F) 100/5 mcg MDI|DRUG: Mometasone Furoate/Formoterol Fumarate (MF/F) 200/5 mcg MDI
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Safety, Tolerability, and Pharmacokinetics of Oral ARN-75039 in Healthy Adult Subjects
Status: SUSPENDED
Conditions: Lassa Virus Infection
Interventions: DRUG: ARN-75039 oral capsules|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cardiopulmonary Effects of Bronchoalveolar Wash on Patients With Acute Respiratory Distress Syndrome
Status: TERMINATED
Conditions: Bronchioalveolar Lavage
Interventions: PROCEDURE: Bronchoalveolar Lavage
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison Between Partial Nephrectomy and Ablation for Renal Tumor
Status: UNKNOWN
Conditions: Renal Cell Carcinoma
Interventions: PROCEDURE: Partial Nephrectomy|PROCEDURE: microwave ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of CPX-351 Monotherapy in Acute Myeloid Leukemia Secondary to Myeloproliferative Neoplasm
Status: RECRUITING
Conditions: Acute Myeloid Leukemia|Myeloproliferative Syndrome
Interventions: DRUG: CPX-351
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single Injection Infromedial Peribulbar Injection in Lacrimal Duct
Status: UNKNOWN
Conditions: Pain Due to Certain Specified Procedures
Interventions: PROCEDURE: infromedial single injection|PROCEDURE: medial canthus injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Endometrial Compaction and Its Influence on Pregnancy Rate in Frozen Embryo Cycle Regimes
Status: TERMINATED
Conditions: Endometrial Disorder|Infertility, Female|IVF|Pregnancy Early
Interventions: DIAGNOSTIC_TEST: Blood test|DIAGNOSTIC_TEST: Ultrasound
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Intermittent Theta Burst Stimulation (iTBS) in Patients With Alcohol Use Disorder
Status: UNKNOWN
Conditions: Alcohol Use Disorder
Interventions: DEVICE: Intermittent Theta Burst Stimulation (iTBS)|DEVICE: Sham stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mulligan Mobilization With Laser for Shoulder Adhesive Capsulitis
Status: COMPLETED
Conditions: Shoulder Adhesive Capsulitis
Interventions: OTHER: mulligan mobilization with low level laser therapy and traditional physical therapy exercises|OTHER: low level laser therapy and traditional physical therapy exercises|OTHER: physical therapy exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: I-care: Stimulating Self-management in Patients With Type 2-diabetes
Status: COMPLETED
Conditions: Diabetes Type 2|Obesity
Interventions: BEHAVIORAL: Cognitive behavior therapy (CBT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effectiveness of NEUROM Combined With tDCS to Guide Motor Recovery in Paraplegics Patients
Status: COMPLETED
Conditions: Spinal Cord Injuries
Interventions: OTHER: Conventional Rehabilitation|OTHER: NEUROM + tDCS|OTHER: NEUROM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Abscopal Effect of Radiotherapy in Combination With rhGM-CSF for Advanced Thymic Epithelial Tumours
Status: UNKNOWN
Conditions: Thymoma
Interventions: RADIATION: Radiotherapy Combined with GM-CSF
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of the xCELLigence System for Quantification of Bacterial Biofilm's Real Time Formation and Antibiotics Selection.
Status: UNKNOWN
Conditions: Chronic Periodontitis|Periodontal Bone Loss|Resistance Bacterial
Interventions: PROCEDURE: SCALE AND ROOT PLANING|DRUG: ADJUNTIVE ANTIBIOTICS|DIAGNOSTIC_TEST: MICROBIAL SAMPLING
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Drug-drug Interaction Study of KL1333 in Healthy Subjects
Status: COMPLETED
Conditions: Mitochondrial Disease
Interventions: DRUG: KL1333|DRUG: Flurbiprofen|DRUG: Dextromethorphan|DRUG: Bupropion|DRUG: Midazolam injection|DRUG: Omeprazole|DRUG: Caffeine|DRUG: Repaglinide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High Radiofrequency Power for Faster and Safer Pulmonary Veins Isolation - a Pilot Observational Study.
Status: COMPLETED
Conditions: Cardiac Arrhythmia|Atrial Fibrillation|Atrial Tachycardia|Esophagus Injury
Interventions: OTHER: Conventional LSI/AI-guided pulmonary veins ablation.|OTHER: High-power pulmonary veins ablation.|OTHER: Esophageal temperature monitoring|DIAGNOSTIC_TEST: Esophageal endoscopy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation and Characterisation of Microplastics and Nanoplastics in Joint Synovial Liquid
Status: NOT_YET_RECRUITING
Conditions: Osteoarthritis, Knee|Knee Arthritis|Gout Arthritis|Microcrystal Disease
Interventions: DIAGNOSTIC_TEST: Synovial fluid analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Reducing Sedentary Behaviour With Technology
Status: COMPLETED
Conditions: Fatigue|Prostate Cancer|Breast Cancer|Sedentary Behaviour|Physical Activity
Interventions: OTHER: Wearable Technology - Garmin Vivosmart|OTHER: Online Educational Group|OTHER: Wearable Technology - FitBit Alta|OTHER: Wearable Technology - Polar Loop 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study Comparing Protected Early Weightbearing Versus Non-Weightbearing After Surgery for Achilles Tendon Rupture
Status: COMPLETED
Conditions: Achilles Tendon Rupture
Interventions: PROCEDURE: Protected early weightbearing/Achilles tendon surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Anrotenib Plus Toripalimab Versus Toripalimab in Patients With Advanced Esophageal Squamous Cell Carcinoma
Status: UNKNOWN
Conditions: Esophageal Squamous Cell Carcinoma
Interventions: DRUG: Anrotenib plus Toripalimab|DRUG: Toripalimab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Intraoperative HR and RR Acquired Via ATLASense Raphael PolyMonitor and Standard Intraoperative Monitors
Status: COMPLETED
Conditions: Intraoperative Monitoring
Interventions: DEVICE: ATLASense RAPHAEL PolyMonitor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Effect of Konjac Grain in the Post-prandial Glycaemic Response of Healthy Subjects
Status: NOT_YET_RECRUITING
Conditions: Diet, Healthy
Interventions: DIETARY_SUPPLEMENT: Konjac Grain
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Ultrasound-Guided Technique in Distal Radial Artery Catheterization Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Coronary Arteriography|Distal Radial Artery|Percutaneous Coronary Intervention|Ultrasonography, Doppler
Interventions: PROCEDURE: Perform distal radial arterial cannulation using modified ultrasound-guided dynamic needle tip positioning technique|PROCEDURE: Palpation guided puncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Comparison of New Suture Anchor Technique for Bony Mallet Injury Versus Conservative Treatment
Status: COMPLETED
Conditions: Finger Injuries|Finger Fracture|Finger Mallet
Interventions: PROCEDURE: Suture anchor technique|PROCEDURE: Conservative Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Peripheral Body Fat Distribution After Switching Zidovudine and Lamivudine to Truvada
Status: COMPLETED
Conditions: HIV-1
Interventions: DRUG: Truvada|DRUG: Zidovudine/lamivudine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Therapy of Early Chronic Phase CML With Higher-Dose Gleevec, Alpha Interferon, and Low-Dose Ara-C
Status: TERMINATED
Conditions: Myelogenous Leukemia, Chronic, Chronic Phase
Interventions: DRUG: Gleevec
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Assessement of Glazed Versus Polished Lithium Disilicate Crowns in Surface Roughness and Enamel Antagonists Wear
Status: UNKNOWN
Conditions: Tooth Decay
Interventions: OTHER: polished emax Press
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Headache After Diagnostic Lumbar Puncture
Status: COMPLETED
Conditions: Post-Lumbar Puncture Headache
Interventions: DEVICE: Sprotte 25G needle, stylet reinserted|DEVICE: Sprotte 25G needle, stylet not reinserted|DEVICE: Sprotte 22G needle, stylet reinserted|DEVICE: Sprotte 22G needle, stylet not reinserted|DEVICE: Spinocan 25G needle, stylet reinserted|DEVICE: Spinocan 25G needle, stylet not reinserted
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study to Evaluate Absorption, Metabolism, and Excretion, of TAK-994 in 6 Healthy Male Adults
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: TAK-994 Oral Tablet|DRUG: [14C]TAK-994 Intravenous Infusion|DRUG: [14C]TAK-994 Oral Suspension
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Open-Label Study of H5 Vaccine in Participants of Protocol 04-077
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Inactivated Influenza A/H5N1 Vaccine (sanofi pasteur)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Incidence of Incomplete Postoperative Neuromuscular Recovery From Anesthesia (P07535)(Completed)
Status: COMPLETED
Conditions: Neuromuscular Blockade
Interventions: OTHER: Neuromuscular Blocking Agent (NMBA)|OTHER: Neuromuscular Blocking Agent (NMBA)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Lirilumab and Nivolumab With 5-Azacitidine in Patients With Myelodysplastic Syndromes (MDS)
Status: TERMINATED
Conditions: Leukemia
Interventions: DRUG: Lirilumab|DRUG: Nivolumab|DRUG: Azacitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exercise and the Sleep for the Sarcopenic Elderly
Status: COMPLETED
Conditions: Sarcopenia|Sleep|Physical Activity
Interventions: OTHER: Sleep|OTHER: Resistance Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Colchicine for Acute Coronary Syndromes
Status: UNKNOWN
Conditions: Acute Coronary Syndrome
Interventions: DRUG: Colchicine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Non-Interventional Study of the Use of Alogliptin and Alogliptin Fixed-Dose Combinations With Pioglitazone and With Metformin in Standard Clinical Practice
Status: TERMINATED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Alogliptin|DRUG: Alogliptin FDC With Pioglitazone|DRUG: Alogliptin FDC With Metformin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pain Severity in Flapless Dental Implant Placement Using Laser
Status: COMPLETED
Conditions: Jaw, Edentulous, Partially
Interventions: DEVICE: Laser-induced Incision|PROCEDURE: Punch Incision|PROCEDURE: Implant Placement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial on Short-chain Fructooligosaccharides, Microbiota, and Constipation in Adults
Status: COMPLETED
Conditions: Functional Constipation
Interventions: DIETARY_SUPPLEMENT: sc-FOS 2g/day|DIETARY_SUPPLEMENT: sc-FOS 4g/day|DIETARY_SUPPLEMENT: sc-FOS 8g/day|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Aesthetic Outcomes of Single Tooth Implant-supported Restorations in the Anterior Maxilla With Either White Zirconia or Fluorescent White Zirconia Abutments
Status: COMPLETED
Conditions: Edentulous Alveolar Ridge in the Aesthetic Zone
Interventions: OTHER: Implant placement and prothesis made with different types of abutment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study of the Interleukin-6 Receptor Inhibitor Tocilizumab in Combination With Ipilimumab and Nivolumab in Patients With Unresectable Stage III or Stage IV Melanoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Melanoma
Interventions: DRUG: Ipilimumab|DRUG: Nivolumab|DRUG: Tocilizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Nebulization of Alkaline Solution on Treating XDRAB Pneumonia With C/S Plus Minocycline
Status: UNKNOWN
Conditions: Pneumonia
Interventions: DRUG: C/S plus minocycline.|DRUG: nebulization with pH 7.4 solution|DRUG: nebulization with pH 7.8 solution|DRUG: No nebulization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Beta- Probe and Surgery in GEP NET: Evaluation of a New Probe
Status: COMPLETED
Conditions: Neuroendocrine Tumors
Interventions: DRUG: Y90-DOTA-Tyr3-Octreotide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: General Anesthesia Versus Locoregional Anesthesia for Evacuation of Chronic Subdural Hematoma
Status: UNKNOWN
Conditions: Chronic Subdural Hematoma
Interventions: DRUG: All General anesthesia|DRUG: All Locoregional anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety, Tolerability, and Immunogenicity of COVID-19 Vaccine, CT-COV-21 Extension Study
Status: COMPLETED
Conditions: Covid19 Vaccine
Interventions: BIOLOGICAL: MVC-COV1901(S protein with adjuvant)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effects of Bowen's Therapy and Post Isometric Relaxation Techniques in Patients of Temporomandibular Joint Disorder
Status: UNKNOWN
Conditions: Temporomandibular Joint Disorders
Interventions: OTHER: Bowen's therapy|OTHER: Post isometric relaxation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Molecular Profiling and Matched Targeted Therapy for Patients With Metastatic Melanoma
Status: RECRUITING
Conditions: Melanoma
Interventions: DRUG: Standard therapy or clinical trial|DRUG: Matched targeted therapy|DRUG: Trametinib and / or supportive care|DRUG: CDK4/6 and MEK inhibitor|DRUG: Compassionate Access Targeted Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Early and Delayed Time-restricted Eating in Adults With Overweight and Obesity
Status: COMPLETED
Conditions: Time Restricted Feeding|Intermittent Fasting|Obesity|Overweight and Obesity
Interventions: BEHAVIORAL: Dietary Approach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: RISE (Rehabilitation Intervention for People With Schizophrenia in Ethiopia)
Status: COMPLETED
Conditions: Schizophrenia Spectrum Disorder|Schizophrenia|Schizoaffective Disorder|Schizophreniform Disorder
Interventions: BEHAVIORAL: Community-based rehabilitation|OTHER: Facility based care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Mechanisms of Specific Trunk Exercises in Low Back Pain
Status: COMPLETED
Conditions: Low Back Pain
Interventions: OTHER: Physical Therapy rehabilitation: Stabilization exercises.|OTHER: Physical Therapy rehabilitation. Movement System Impairment (MSI) classification based exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Eribulin Mesylate Administered in Combination With Gemcitabine Plus Cisplatin Versus Gemcitabine Plus Cisplatin Alone as First-Line Therapy for Locally Advanced or Metastatic Bladder Cancer
Status: TERMINATED
Conditions: Bladder Cancer
Interventions: DRUG: Gemcitabine|DRUG: E7389|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study To Assess the Safety of OnabotulinumtoxinA (BOTOX) Intramuscular Injection in Adult Participants With Platysma Prominence
Status: COMPLETED
Conditions: Platysma Prominence
Interventions: DRUG: BOTOX
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Genicular Nerve Blocks for Anterior Cruciate Ligament Knee Surgery
Status: RECRUITING
Conditions: ACL|Anterior Cruciate Ligament Injuries
Interventions: DRUG: Genicular Nerve Block with bupivacaine and preservative free dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: COSOPT-S® Treatment Versus Acetazolamide Before Trabeculectomy
Status: COMPLETED
Conditions: Glaucoma
Interventions: DRUG: Trabeculectomy with preoperative Diamox/DexaEDO treatment|DRUG: Trabeculectomy with preoperative Cosopt S treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: D-serine Supplementation for Depression
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DIETARY_SUPPLEMENT: D-serine|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of PBI-4050 on the Pharmacokinetics of Midazolam in Heathy Adult Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: PBI-4050 and midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Mechanism of cTBS Targeting Dentate Nucleus for DRE
Status: COMPLETED
Conditions: Transcranial Magnetic Stimulation|Drug Resistant Epilepsy|Cerebellum
Interventions: DEVICE: transcranial magnetic stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Effects of Omega-3 Status and Supplementation on Tendon Structure in Competitive Athletes
Status: UNKNOWN
Conditions: Tendon Injuries|Inflammation
Interventions: DIETARY_SUPPLEMENT: Omega-3|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Irinotecan Hydrochloride, Temozolomide, and Dinutuximab With or Without Eflornithine in Treating Patients With Relapsed or Refractory Neuroblastoma
Status: ACTIVE_NOT_RECRUITING
Conditions: High Risk Neuroblastoma|Recurrent Neuroblastoma|Refractory Neuroblastoma
Interventions: BIOLOGICAL: Dinutuximab|DRUG: Eflornithine Hydrochloride|DRUG: Irinotecan Hydrochloride|BIOLOGICAL: Sargramostim|DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness and Safety of Bushen Culuan Decoction for Anovulatory Infertility
Status: UNKNOWN
Conditions: Anovulatory Infertility|Abnormal Uterine Bleeding-Ovulatory Disorders|Polycystic Ovarian Syndrome|Hyperprolactinemia|Luteinized Unruptured Follicle Syndrome|Corpus Luteum Insufficiency|Ovarian Insufficiency
Interventions: DRUG: experimental group: Bushen Culuan Decoction and Clomiphene Citrate Tablets placebo|DRUG: control group: Clomiphene Citrate Tablets and Bushen Culuan Decoction placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Y-90 With Durvalumab/Gem/Cis in Intrahepatic Cholangio
Status: RECRUITING
Conditions: Bile Duct Cancer|Cholangiocarcinoma|Cholangiocarcinoma Non-resectable|Cholangiocarcinoma Metastatic|Metastatic Intrahepatic Cholangiocarcinoma
Interventions: DRUG: Gemcitabine|DRUG: Cisplatin|DRUG: Durvalumab|RADIATION: Yttrium-90
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Multiple Rising Oral Doses of BI 1021958 in Otherwise Healthy Controlled Asthmatic Subjects
Status: COMPLETED
Conditions: Healthy|Asthma
Interventions: DRUG: Placebo to BI 1021958 qd|DRUG: BI 1021958 bid|DRUG: Placebo to BI 1021958 bid|DRUG: BI 1021958 qd
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Therapeutic Intervention of Eriocitrin in the Reduction of Hyperglycemia in Pre-diabetic Individuals
Status: COMPLETED
Conditions: Pre Diabetes
Interventions: DIETARY_SUPPLEMENT: Eriocitrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nerve Conduction Block Using Transcutaneous Electrical Currents
Status: UNKNOWN
Conditions: Nerve Block|Electric Stimulation
Interventions: DEVICE: High-Frequency Stimulation|DEVICE: sham Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: HIPEC After Secondary Cytoreductive Operation in Patients With Platinum-sensitive Recurrence of Ovarian Carcinoma
Status: WITHDRAWN
Conditions: Epithelial Ovarian Cancer|Peritoneal Cancer|Fallopian Tube Cancer
Interventions: PROCEDURE: HIPEC|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial Comparing Different Stimulation Paradigms in Patients Treated With Vagus Nerve Stimulation for Refractory Epilepsy
Status: COMPLETED
Conditions: Epilepsy
Interventions: PROCEDURE: Vagus nerve stimulation paradigm #1|PROCEDURE: Vagus nerve stimulation paradigm #2|PROCEDURE: Vagus nerve stimulation paradigm #3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Ultrasound Therapy on Cartilage Healing in Patients With Knee Osteoarthritis
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: DEVICE: Low intensity pulsed ultrasound therapy|DEVICE: Sham Low intensity pulsed ultrasound therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Moving 2 Mindful (M2M) Study: Mindfulness Group + Ecological Momentary Intervention
Status: TERMINATED
Conditions: Anxiety|Stress
Interventions: BEHAVIORAL: Learning to BREATHE Plus|BEHAVIORAL: Health and wellness
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Characterize Regimens of Basal Insulin Intensified With Either Symlin® or Rapid Acting Insulin in Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: pramlintide acetate (Symlin)|DRUG: rapid acting insulin (Humalog® [insulin lispro], Novolog® [insulin aspart], or Apidra® [insulin glulisine])|DRUG: basal insulin (Lantus® [insulin glargine], or Levemir® [insulin detemir])
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Insulin Glargine Injection Treatment in Place of Thiazolidinedione (TZD), Sulfonylurea, or Metformin in Triple Agent Therapy for Type 2 Diabetes Mellitus (T2DM) Adult Subjects With Unsatisfactory Control
Status: TERMINATED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Insulin Glargine|DRUG: Insulin Glulisine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Immunonutrition on Biomarkers in Traumatic Brain Injury
Status: COMPLETED
Conditions: Traumatic Brain Injury|Immuno-Deficiency|Nutrient Deficiency
Interventions: DIETARY_SUPPLEMENT: Neomune|DIETARY_SUPPLEMENT: Fresubin® HP energy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy, Radiation Therapy, and Cetuximab in Treating Patients With the Head and Neck Cancer
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: BIOLOGICAL: cetuximab|DRUG: cisplatin|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Antioxidants on MRI Detectable Early Stage Prostate Cancer Among Men on Active Surveillance
Status: COMPLETED
Conditions: Cancer of the Prostate|Prostate Cancer|Prostatic Neoplasms
Interventions: DIETARY_SUPPLEMENT: Lycopene, Vitamin D3, Selenium, Green Tea Extract, Vitamin E|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Predictability of Preoperative Hemoglobin A1c in Diabetic Patients Underwent Off-Pump Coronary Artery Bypass Surgery: A Retrospective Study.
Status: UNKNOWN
Conditions: Coronary Artery Disease, Diabetes
Interventions: OTHER: Off-Pump Coronary Artery Bypass (OPCAB) surgery
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Zirconia Reinforced Glass Ionomer in MIH
Status: COMPLETED
Conditions: Molar Incisor Hypomineralization
Interventions: OTHER: zirconomer|OTHER: HVGI-Equia Forte
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigation of Myocardial Protection Efficacy of Cardioplegia Solutions Used in Open Heart Surgery
Status: COMPLETED
Conditions: Cardiovascular Diseases|Myocardial Reperfusion Injury
Interventions: PROCEDURE: Patients with coronary artery bypass surgery routine procedural administration of cardioplegia solutions|PROCEDURE: Patients who underwent heart valve surgery without coronary artery disease routine procedural administration of cardioplegia solutions
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Evaluate the Efficacy and Safety of Bimekizumab Compared to Ustekinumab in Children and Adolescents From 6 Years to Less Than 18 Years of Age With Moderate to Severe Plaque Psoriasis
Status: RECRUITING
Conditions: Moderate to Severe Plaque Psoriasis
Interventions: DRUG: bimekizumab|DRUG: ustekinumab|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT