pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Study to Evaluate is ECV Success is Improved and the Side Effects Reduced With the Use of IV NTGL Versus Terbutaline
Status: TERMINATED
Conditions: External Cephalic Version
Interventions: DRUG: Intravenous Terbutaline|DRUG: Intravenous Nitroglycerine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I Study of Anti-CD22 Chimeric Receptor T Cells in Patients With Relapsed/Refractory Hairy Cell Leukemia and Variant
Status: RECRUITING
Conditions: Hairy Cell Leukemia|Hairy Cell Leukemia Variant
Interventions: BIOLOGICAL: CD22CART cell infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: miRNA-155 Assay Before and After Immunotherapy and Probiotics
Status: COMPLETED
Conditions: Allergic Rhinitis
Interventions: DRUG: Lacteol fort|DRUG: Standardized Timothy Grass Pollen|DRUG: Lacteol fort and Standardized Timothy Grass Pollen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Dose Finding Study of RAD001 (Everolimus, Afinitor®) in Combination With BEZ235 in Patients With Advanced Solid Tumors
Status: COMPLETED
Conditions: Advanced Solid Tumors|Metastatic Breast Cancer|Metastatic Renal Cell Carcinoma
Interventions: DRUG: RAD001 + BEZ235
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Preliminary Immunogenicity Study of Inactivated Vaccine for Prevention of Rotavirus Infection
Status: UNKNOWN
Conditions: Rotavirus Infection
Interventions: BIOLOGICAL: Low dosage IRV on a 0- and 28-day schedule|BIOLOGICAL: Medium dosage IRV on a 0- and 28-day schedule|BIOLOGICAL: High dosage IRV on a 0- and 28-day schedule|BIOLOGICAL: Low dosage IRV on a 0- and 28-day schedule|BIOLOGICAL: Medium dosage IRV on a 0- and 28-day schedule|BIOLOGICAL: High dosage IRV on a 0- and 28-day schedule|BIOLOGICAL: Low dosage IRV on a 0- and 28-day schedule|BIOLOGICAL: Medium dosage IRV on a 0- and 28-day schedule|BIOLOGICAL: High dosage IRV on a 0- and 28-day schedule|BIOLOGICAL: Low dosage IRV on a 0- and 28-day schedule|BIOLOGICAL: Medium dosage IRV on a 0- and 28-day schedule|BIOLOGICAL: High dosage IRV on a 0- and 28-day schedule|BIOLOGICAL: Low dosage IRV on a 0- , 28- and 56-day schedule|BIOLOGICAL: Medium dosage IRV on a 0- , 28- and 56-day schedule|BIOLOGICAL: High dosage IRV on a 0- , 28- and 56-day schedule|BIOLOGICAL: Placebo on day 0, 28|BIOLOGICAL: Placebo on day 0, 28, 56
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Interest of Evaluating the Movement of the Center of Mass in a Dynamic Avoidance Task as the Endpoint of the Dynamic Equilibrium of Hemiplegic Patients
Status: COMPLETED
Conditions: Hemiplegic Patients
Interventions: OTHER: Dynamic Avoidance Task|PROCEDURE: physical therapy|DEVICE: 3D motion on optoelectronic device
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Early Use of Botulinum Toxin in Spasticity Post Stroke.
Status: COMPLETED
Conditions: Stroke|Muscle Spasticity|Contracture
Interventions: DRUG: onabotulinumtoxinA|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Omnipaque Versus Gastroview as Oral Contrast for Abdominal and Pelvic CT
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Omnipaque|DRUG: Gastroview
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Intraperitoneal Therapy For Ovarian Cancer With Carboplatin Trial
Status: COMPLETED
Conditions: Epithelial Ovarian Cancer|Fallopian Tube Cancer|Primary Peritoneal Carcinoma
Interventions: DRUG: Paclitaxel(intravenous) + Carboplatin(intravenous)|DRUG: Paclitaxel(intravenous) + Carboplatin(intraperitoneal)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Precision Alemtuzumab Dosing for Allogeneic Hematopoietic Cell Transplantation
Status: RECRUITING
Conditions: Allogeneic Hematopoietic Cell Transplantation
Interventions: DRUG: Alemtuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Collabree: An Intervention to Improve the Regularity of Medication Intake
Status: RECRUITING
Conditions: Hypertension|Medication Adherence
Interventions: BEHAVIORAL: Collabree Mobile Phone Application Medication Adherence Booster (simplified version)|BEHAVIORAL: Collabree Mobile Phone Application Medication Adherence Booster
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Efficacy and Safety of Oral VT-1161 in Patients With Onychomycosis of the Toenail
Status: COMPLETED
Conditions: Onychomycosis
Interventions: DRUG: VT-1161|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Use of High Intensity Interval Training as a Strategy to Minimize the Insulin Resistance Observed in Sleep Deprivation
Status: UNKNOWN
Conditions: Insulin Resistance|Sleep Deprivation
Interventions: OTHER: High Intensity Interval Training
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Transcutaneous Vagal Stimulation (TVS) on Endothelial Function and Arterial Stiffness in HFrEF
Status: COMPLETED
Conditions: Heart Failure With Reduced Ejection Fraction|Endothelial Dysfunction
Interventions: DEVICE: TVS|DEVICE: Sham TVS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Vaginal Axis on MRI in Alternative Apical Prolapse Surgeries to Sacrocolpopexy
Status: COMPLETED
Conditions: Pelvic Organ Prolapse
Interventions: PROCEDURE: laparoscopic lateral suspension|PROCEDURE: laparoscopic pectopexy|PROCEDURE: Sacrospinous ligament fixation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: PROne Positioning in coVID-19 Oxygeno-dependent Patients in Spontaneous Ventilation (PROVID Study)
Status: COMPLETED
Conditions: COVID|ARDS
Interventions: BEHAVIORAL: 1: Prone positioning|BEHAVIORAL: 2: No instruction regarding positioning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Controlled Trial to Evaluate the Effects of GanedenBC30 on the Immune System
Status: COMPLETED
Conditions: HIV Infection|Gastrointestinal Symptoms
Interventions: DIETARY_SUPPLEMENT: GanedenBC30, GBI-30, PTA-6086|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Novel Bionic Foot, AMPfoot 4+
Status: COMPLETED
Conditions: Prosthesis User|Cognitive Change|Physical Activity
Interventions: DEVICE: Ankle Mimicking Prosthetic Foot prototype 4+
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Bortezomib Combined With DAG Regimen in the Treatment of Refractory/Relapsed AML
Status: RECRUITING
Conditions: Bortezomib|Acute Myeloid Leukemia
Interventions: DRUG: DAG pre-excitation regimen with Bortezomib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Healthy Homes, Healthy Habits
Status: ACTIVE_NOT_RECRUITING
Conditions: Obesity|Obesity, Childhood|Obesity; Familial
Interventions: BEHAVIORAL: Home visitation + HABITS program|BEHAVIORAL: Standard home visitation program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Analysis of Competitive Posterior Cruciate Retaining (PCR) and Posterior Stabilized (PS) Total Knee Arthroplasty (TKA)
Status: COMPLETED
Conditions: Knee Osteoarthritis|Total Knee Arthroplasty|Knee
Interventions: DEVICE: Triathlon PCR TKA|DEVICE: Triathlon PS TKA|DEVICE: Persona PCR TKA|DEVICE: Persona PS TKA
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Evaluate the Safety , Tolerability and Efficacy of IBI939 in Combination With Sintilimab in Patients With Advanced Lung Cancer
Status: COMPLETED
Conditions: Advanced Lung Cancer
Interventions: BIOLOGICAL: IBI939|BIOLOGICAL: Sintilimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Food Study of Sertraline Hydrochloride Tablets 100 mg and Zoloft® Tablets 100 mg
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Sertraline Hydrochloride Tablets 100 mg|DRUG: Zoloft® Tablets 100 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Randomized Neoadjuvant Study of Epirubicin and Docetaxel With/Without Capecitabine in Early Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Epirubicin|DRUG: Docetaxel|DRUG: Capecitabine|DRUG: Trastuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aspirin® Plus Rivaroxaban Versus Rivaroxaban Alone for the Prevention of Venous Stent Thrombosis in Patients With PTS
Status: TERMINATED
Conditions: Venous Thromboses|Stent Stenosis
Interventions: DRUG: Aspirin 100mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pembrolizumab in Refractory Advanced Esophageal Cancer
Status: COMPLETED
Conditions: Esophageal Cancer|Squamous Cell Esophagus Cancer|Adenocarcinoma Esophagus
Interventions: DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral Magnesium Pidolate, Hemoglobin SC Disease, MG Pidolate
Status: TERMINATED
Conditions: HEMOGLOBIN SC DISEASE
Interventions: DRUG: Mg Pidolate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of EUS-FNB Biopsy Techniques of Solid Pancreatic Lesions
Status: UNKNOWN
Conditions: Pancreatic Neoplasm
Interventions: DIAGNOSTIC_TEST: Endoscopic ultrasound-guided biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of the Efficacy and Safety of Highly Purified Menotrophin Versus Recombinant Follitropin Alfa
Status: COMPLETED
Conditions: Infertility
Interventions: DRUG: Menotrophin|DRUG: Follitropin alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Saccharomyces Cerevisiae on the Symptoms of Irritable Bowel Syndrome
Status: COMPLETED
Conditions: Irritable Bowel Syndrome
Interventions: DIETARY_SUPPLEMENT: Saccharomyces cerevisiae CNCM I-3856|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Cu-64-PSMA-I&T Positron Emission Tomography (PET) Imaging of Metastatic PSMA Positive Lesions in Men With Prostate Cancer
Status: COMPLETED
Conditions: Metastasis From Malignant Tumor of Prostate (Disorder)
Interventions: DRUG: 64Cu-PSMA I&T
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: B010-A Injection for Treating Patients With GPC3 Positive Advanced Hepatocellular Carcinoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Hepatocellular Carcinoma
Interventions: BIOLOGICAL: Biological/Vaccine: Low-dose group|BIOLOGICAL: Biological/Vaccine: Mid-dose group|BIOLOGICAL: Biological/Vaccine: High-dose group
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fish or Nuts? Dietary Effects on Cardiometabolic Risk Factors and Persistent Organic Pollutants
Status: COMPLETED
Conditions: Obesity|Metabolic Syndrome|Diabetes
Interventions: OTHER: The fatty fish group|OTHER: The nut group|OTHER: The control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Early Hippocampal Avoidance Prophylactic Cranial Irradiation in Patients With LD SCLC
Status: COMPLETED
Conditions: Small-Cell Lung Cancer
Interventions: RADIATION: Irradiation: HA-PCI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I Study to Determine the Absorption, Distribution, Metabolism and Excretion of Esreboxetine
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: [14C]-esreboxetine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Modulation of Micro-RNA Pathways by Gemfibrozil in Predementia Alzheimer Disease
Status: COMPLETED
Conditions: Preclinical Alzheimer's Disease
Interventions: DRUG: Gemfibrozil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: CM-101 in NASH Patients - The SPLASH Study
Status: COMPLETED
Conditions: Nonalcoholic Steatohepatitis
Interventions: BIOLOGICAL: 5 mg/kg CM-101|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Developing New Treatments for Tourette Syndrome: Therapeutic Trials With Modulators of Glutamatergic Neurotransmission
Status: COMPLETED
Conditions: Tourette Syndrome
Interventions: DRUG: D-serine|DRUG: Riluzole|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of 12-week Dietary Intake of Syrup Containing CoQ10 and Collagen on Dermis Density and Other Skin Parameters
Status: COMPLETED
Conditions: Dermis Density|Trans Epidermal Water Loss (TEWL)|Skin Hydration|Wrinkles|Dermis Thickness
Interventions: DIETARY_SUPPLEMENT: Test syrup containing CoQ10 and collagen|DIETARY_SUPPLEMENT: Placebo syrup
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: DOCTOR Compare - A Study in the "DOCTOR" Series (Does Optical Coherence Tomography Optimize Revascularization?"
Status: COMPLETED
Conditions: Coronary Disease|Myocardial Infarction|Atherosclerosis
Interventions: PROCEDURE: Comparison of OCT scans|PROCEDURE: Comparison of Intra Vascular Optical Coherence Tomography Systems for Assessment of Coronary Tissue, Stents and Scaffolds - DOCTOR Compare
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phase 2 Study of KHK7580
Status: COMPLETED
Conditions: Secondary Hyperparathyroidism
Interventions: DRUG: Placebo|DRUG: KHK7580 low dose|DRUG: KHK7580 middle dose|DRUG: KHK7580 high dose|DRUG: KRN1493
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of TAK-279 in Adult Participants With Generalized Pustular Psoriasis or Erythrodermic Psoriasis
Status: RECRUITING
Conditions: Generalized Pustular Psoriasis|Erythrodermic Psoriasis
Interventions: DRUG: TAK-279
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testing the Effectiveness of the Full and Abridged Relationship Smarts Curriculum for 9th Grade Students
Status: COMPLETED
Conditions: Attitudes|Knowledge
Interventions: BEHAVIORAL: Healthy Relationship Education|BEHAVIORAL: Job Readiness Curriculum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: "Pilot Study: A Comparison of the Bouquet Speculum and the Traditional 2-Bladed Speculum"
Status: TERMINATED
Conditions: Pelvic Exam
Interventions: DEVICE: Bouquet speculum|DEVICE: Traditional plastic 2-blade disposable speculum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of SMS Reminder and Free Eye Drops on Follow-up Adherence After Trabeculectomy Surgery in Rural China
Status: COMPLETED
Conditions: Glaucoma|Adherence
Interventions: OTHER: SMS and free eye drops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effects of Triptorelin When Given Every 6-months Under the Skin to Adult Males With Cancer in the Prostate
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: Triptorelin embonate 22.5 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Therapeutic Optimization Study Based on MR Enterocolonography in Patients With Crohn's Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Crohn Disease
Interventions: DRUG: azathioprine or adalimumab and infliximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Standard-dose Versus High-dose Flu Vaccine in Solid Organ Transplant.
Status: COMPLETED
Conditions: Influenza, Human|Transplantation Infection
Interventions: BIOLOGICAL: influenza trivalent inactive vaccine|BIOLOGICAL: influenza trivalent inactive vaccine high dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Dietary Methionine Restriction Plus Temozolomide for Recurrent GBM
Status: TERMINATED
Conditions: Glioblastoma Multiforme
Interventions: DRUG: Temodar (Temozolomide)|DIETARY_SUPPLEMENT: Hominex-2
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Setanaxib Co-Administered With Pembrolizumab in Patients With Recurrent or Metastatic Squamous Cell Carcinoma of Head and Neck (SCCHN)
Status: ACTIVE_NOT_RECRUITING
Conditions: Squamous Cell Carcinoma of Head and Neck
Interventions: DRUG: Setanaxib|BIOLOGICAL: Pembrolizumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects Of Latissimus Dorsi Stretching On Functional Disability Related To Chronic Low Back Pain
Status: COMPLETED
Conditions: Mechanical Low Back Pain
Interventions: OTHER: Spinal Stabilization Exercises (SSE)|OTHER: Spinal Stabilization Exercises (SSE) & Latissimus Dorsi Stretching (LDS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Joint Transition Visits on Quality of Life in Inflammatory Bowel Diseases (TRANS-IBD)
Status: NOT_YET_RECRUITING
Conditions: Inflammatory Bowel Diseases|Crohn's Disease|Ulcerative Colitis
Interventions: OTHER: joint visits
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Efficacy and Safety of Quadratus Lumborum Block Versus Pericapsular Nerve Group Block in Pediatric Hip Surgery
Status: COMPLETED
Conditions: Pain, Postoperative|Developmental Dislocation of Hip
Interventions: PROCEDURE: TQL block|PROCEDURE: PENG block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study Using [18F]F AraG PET to Evaluate Response to Checkpoint Inhibitor Therapy(CkIT) in Patients With Solid Tumors
Status: RECRUITING
Conditions: Correlate Tracer Uptake to TCell Tumor Infiltration & CkIT Benefit
Interventions: DRUG: [18F]F-AraG
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: An Extension Study for Patients Previously Enrolled in Studies With Pelabresib
Status: NOT_YET_RECRUITING
Conditions: Hematologic Malignancy|Solid Tumor|Advanced Malignancies
Interventions: DRUG: Pelabresib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate of the Safety and Effectiveness of Asoprisnil in Treating Women With Uterine Fibroids
Status: COMPLETED
Conditions: Fibroid Uterus|Leiomyoma|Menorrhagia|Metrorrhagia|Uterine Fibroids
Interventions: DRUG: Asoprisnil|DRUG: Asoprisnil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ticagrelor Loading Dose Versus Clopidogrel Loading and Reloading With Ticagrelor.
Status: COMPLETED
Conditions: Platelet Reactivity
Interventions: DRUG: Clopidogrel and Ticagrelor|DRUG: Ticagrelor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Topographic and Quantitative Differences of the Mandibular Symphysis Area Between Males and Females Egyptians Using CBCT Scans: a Cross-sectional Study
Status: NOT_YET_RECRUITING
Conditions: Mandibular Symphysis, Block Bone Graft, Mandibular Incisive Canal, and CBCT
Interventions: RADIATION: CBCT
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: 18F-FDG PET Scan and MRI Diffusion.Evaluation of the Early Therapeutic Response of Diffuse Large B-cell Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Diffuse Large B Cell Lymphoma
Interventions: OTHER: 18F-FDG PET SCAN|OTHER: MRI DIFFUSION
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Medically Assisted Fertilization Techniques in Systemic Immunoreumatologic Diseases
Status: RECRUITING
Conditions: Rheumatic Diseases|Fertility Disorders|Pregnancy, High Risk|Pregnancy Complications|Immunologic Disease
Interventions: OTHER: collection and analysis of treatments and procedures already performed by normal clinical practice
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Double-Blind, Randomized, Placebo-Controlled Study Evaluating the Nutritional Supplement Lumenato and Its Impact on Skin Parameters in Healthy Female Subjects
Status: WITHDRAWN
Conditions: Skin
Interventions: DIETARY_SUPPLEMENT: Lumenato
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The DIVINE Study: DIetary Management of Glucose VarIability iN thE ICU
Status: COMPLETED
Conditions: Critically Ill Mechanically Ventilated Subjects
Interventions: OTHER: Peptamen Bariatric|OTHER: Replete
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: FDA "Breakthrough Drugs": A Trial Testing the Effect of Alternative Language on Public Perceptions
Status: COMPLETED
Conditions: Prescription Drugs
Interventions: OTHER: Facts only|OTHER: promising language|OTHER: breakthrough only|OTHER: breakthrough with "may" warning|OTHER: breakthrough with "is" warning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose:
Clinical trial: Efficacy Assessment of a Novel 3D Cartography-based Targeted Focal Microwave Therapy in Men With Localized Intermediate-risk Prostate Cancer
Status: UNKNOWN
Conditions: Prostate Cancer
Interventions: DEVICE: Targeted microwave ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Monotherapy Rapastinel in the Prevention of Relapse in Patients With Major Depressive Disorder (MDD)
Status: TERMINATED
Conditions: Depressive Disorder, Major
Interventions: DRUG: Rapastinel|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Brexucabtagene Autoleucel (KTE-X19) for the Treatment of Individuals With Relapsed/Refractory B-Cell Malignancies
Status: APPROVED_FOR_MARKETING
Conditions: Relapse/Refractory Mantle Cell Lymphoma
Interventions: BIOLOGICAL: Brexucabtagene Autoleucel (KTE-X19)|DRUG: Fludarabine|DRUG: Cyclophosphamide
Study Type: EXPANDED_ACCESS
Clinical trial: Comparison Between Two Endotracheal Tube Cuff Inflation Methods
Status: COMPLETED
Conditions: Endotracheal Cuff Pressure|Flow-Volume Loop Guided|Stethoscope-guided
Interventions: OTHER: Endotracheal cuff inflation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Phase 3 Study of Cx601 in Participants With Complex Perianal Fistulising Crohn's Disease
Status: COMPLETED
Conditions: Complex Perianal Fistulas in Adult Participants With Crohn's Disease
Interventions: BIOLOGICAL: Darvadstrocel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluate Umbilical Cord-derived Allogeneic Mesenchymal Stem Cells for the Treatment of Bradykinesia
Status: UNKNOWN
Conditions: Bradykinesia
Interventions: BIOLOGICAL: MSCTC-0010
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Virtual Histology Findings and Effects of Varying Doses of Atorvastatin Treatment
Status: COMPLETED
Conditions: Coronary Disease|Ultrasonography, Interventional|Hydroxymethylglutaryl-CoA Reductase Inhibitors
Interventions: DRUG: Atorvastatin 10mg versus 40mg.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Multicenter, Prospective, Phase II Study of Zanubrutinib for Maintenance in Patients With Mantle Cell Lymphoma
Status: RECRUITING
Conditions: Mantle Cell Lymphoma|Maintenance Therapy
Interventions: DRUG: Zanubrutinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety of Injection of Placental Mesenchymal Stem Cell Derived Exosomes for Treatment of Resistant Perianal Fistula in Crohn's Patients
Status: UNKNOWN
Conditions: Perianal Fistula in Patients With Crohn's Disease
Interventions: OTHER: placenal MSC derived exosomes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fenretinide Lym-X-Sorb + Ketoconazole + Vincristine for Recurrent or Resistant Neuroblastoma
Status: TERMINATED
Conditions: Recurrent Neuroblastoma|Neuroblastoma
Interventions: DRUG: Fenretinide/LXS Oral Powder|DRUG: Ketoconazole|DRUG: Vincristine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety of MenACWY in Infants (6 & 12 Months)
Status: COMPLETED
Conditions: Meningococcal Meningitis
Interventions: BIOLOGICAL: MenACWY-CRM|BIOLOGICAL: MenC-CRM|BIOLOGICAL: DTaP-Hib-IPV|BIOLOGICAL: PC7|BIOLOGICAL: MMR|BIOLOGICAL: Varicella
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to Assess the Safety of a Potential New Drug in Comparison to the Standard Practice of Dosing With Warfarin for Non-valvular Atrial Fibrillation
Status: COMPLETED
Conditions: Atrial Fibrillation|Thromboembolism
Interventions: DRUG: Edoxaban (DU-176b)|DRUG: Edoxaban (DU-176b)|DRUG: Edoxaban (DU-176b)|DRUG: Edoxaban (DU-176b)|DRUG: warfarin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Clinical Study to Evaluate the Possible Efficacy and Safety of L- Carnitine and Sildenafil in Children Having Beta Thalassemia With Increased Tricuspid Regurgitant Jet Velocity
Status: RECRUITING
Conditions: Beta Thalassemia With Increased Tricuspid Regurgitant Jet Velocity
Interventions: DRUG: L_carnitine|DRUG: Sildenafil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Chiropractic Care in Adults With Subclinical Spinal Pain
Status: COMPLETED
Conditions: Subclinical Spinal Pain
Interventions: OTHER: Chiropractic Care|OTHER: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: OMNI in Open-angle Glaucoma Treatment
Status: UNKNOWN
Conditions: Open Angle Glaucoma|Cataract|Eye Diseases|Glaucoma
Interventions: PROCEDURE: OMNI as a standalone procedure|PROCEDURE: OMNI combined with cataract surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radiation Therapy to the Abdomen Plus Docetaxel in Treating Patients With Recurrent or Persistent Advanced Ovarian, Peritoneal, or Fallopian Tube Cancer
Status: COMPLETED
Conditions: Fallopian Tube Carcinoma|Primary Peritoneal Carcinoma|Recurrent Ovarian Carcinoma|Stage III Ovarian Cancer|Stage IV Ovarian Cancer
Interventions: RADIATION: 3-Dimensional Conformal Radiation Therapy|DRUG: Chemosensitization/Potentiation Therapy|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Does Micropattern on Urinary Catheter Surface Reduce Urinary Tract Infections?
Status: COMPLETED
Conditions: Catheter Associated Urinary Tract Infections
Interventions: DEVICE: Sharklet Catheter insertion|DEVICE: Silicone Foley Catheter insertion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: German Multicenter Trial for Treatment of Newly Diagnosed Acute Lymphoblastic Leukemia in Adults (06/99)
Status: COMPLETED
Conditions: Adult Acute Lymphocytic Leukemia
Interventions: DRUG: Dexamethasone / Prednisolone|DRUG: Cyclophosphamide|DRUG: Methotrexate|DRUG: Vincristine / Vindesine|DRUG: Daunorubicin|DRUG: Asparaginase|DRUG: G-CSF|DRUG: Cytarabine|DRUG: 6-Mercaptopurine|DRUG: VP16|DRUG: Adriamycin|DRUG: Thioguanine|DRUG: VM26|DRUG: Idarubicin|DRUG: Fludarabine|DRUG: Ifosfamide|PROCEDURE: CNS irradiation|PROCEDURE: Mediastinal irradiation (if residual tumor)|PROCEDURE: stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Open-Label Study of Ruxolitinib Given With Chemotherapy in Patients With Advanced Solid Tumors
Status: TERMINATED
Conditions: Solid Tumors|Pancreatic Cancer
Interventions: DRUG: ruxolitinib|DRUG: gemcitabine|DRUG: nab-paclitaxel|DRUG: filgrastim
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Learn How the Study Medicine Called Zavegepant is Taken Up Into Blood and Breast Milk of Healthy Breast-Feeding Women
Status: RECRUITING
Conditions: Healthy
Interventions: DRUG: Zavegepant 10mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Efficacy of Zonisamide an Antiepileptic Drug as Monotherapy or Adjunctive Therapy in Treatment of Adult Patients With Partial, Generalized or Combined Seizures.
Status: COMPLETED
Conditions: Partial, Generalized and Combined Seizures
Interventions: DRUG: zonisamide
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: First-in-Human Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Mirvetuximab Soravtansine in Adults With Ovarian Cancer and Other Folate Receptor 1 (FOLR1)-Positive Solid Tumors
Status: COMPLETED
Conditions: Tumors
Interventions: DRUG: Mirvetuximab soravtansine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dissemination of an Adolescent Obesity Prevention Intervention to Louisiana Schools
Status: ENROLLING_BY_INVITATION
Conditions: Treatment (ProudMe)|Waitlist Control
Interventions: BEHAVIORAL: ProudMe|BEHAVIORAL: Waitlist Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Pulsatile GnRH in Anovulatory Infertility
Status: UNKNOWN
Conditions: Hypogonadotropic Hypogonadism|Amenorrhea|Kallmann's Syndrome
Interventions: DRUG: GnRH|DEVICE: Pump
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Irritation Potential of Products in Human Eyes.
Status: COMPLETED
Conditions: Sunscreening Agents
Interventions: OTHER: Sunscreen Spray SPF50 Z15-034(BAY987516)|OTHER: Shampoo Control|OTHER: Sunscreen Spray SPF50 Z15-038(BAY987516)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Single Dose Study to Determine the Safety, Tolerability, and Pharmacokinetic Properties of Lorcaserin Hydrochloride (BELVIQ) in Obese Adolescents From 12 to 17 Years of Age
Status: COMPLETED
Conditions: Pharmacokinetics in Obese Adolescents
Interventions: DRUG: Lorcaserin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Dopaminergic Effects on Cortical Function in Tourette's (Levodopa Protocol)
Status: COMPLETED
Conditions: Tourette Syndrome
Interventions: DRUG: levodopa solution 2mg/ml for i.v. use|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Temsirolimus in Treating Patients With Relapsed or Refractory Multiple Myeloma
Status: COMPLETED
Conditions: Refractory Multiple Myeloma|Stage I Multiple Myeloma|Stage II Multiple Myeloma|Stage III Multiple Myeloma
Interventions: DRUG: temsirolimus|OTHER: pharmacological study|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Refractory Gout With ACTH or Methylprednisolone
Status: UNKNOWN
Conditions: Gout
Interventions: DRUG: Adrenocorticotropic Hormone|DRUG: Methylprednisolone Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparision of EUS-FNB Techniques for Diagnose of Solid Pancreatic Lesions
Status: NOT_YET_RECRUITING
Conditions: Solid Pancreatic Lesions|EUS-FNB
Interventions: PROCEDURE: Wet suction|PROCEDURE: Dry suction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of GRN163L With Paclitaxel and Bevacizumab to Treat Patients With Locally Recurrent Or Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: GRN163L
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multicenter Active Comparator Study of HC-ER in Adults Following Bunionectomy Surgery
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: 10 mg HC-ER|DRUG: 20 mg HC-ER|DRUG: 30 mg HC-ER|DRUG: 40 mg HC-ER|DRUG: 10 mg HC / 325 mg APAP|DRUG: Matching Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Phase Ib/II Trail of Neoadjuvant of Tislelizumab Combined With Palbociclib in Patients With Platinum-refractory Bladder Urothelial Carcinoma
Status: RECRUITING
Conditions: Bladder Cancer
Interventions: DRUG: Tislelizumab combined with two predefined dose groups of palbociclib|DRUG: RP2D dose Of Tislelizumab combined with palbociclib was selected for phase II clinical trial.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Ataciguat Versus Placebo in Patients With Neuropathic Pain
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: ataciguat (HMR1766)|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Versamed iVent in the Transport of Patients Receiving Mechanical Ventilation
Status: WITHDRAWN
Conditions: Respiration, Artificial
Interventions: DEVICE: Use of ventilator during patient transport (Versamed iVent)|OTHER: Bag-valve ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety of Trifluridine/Tipiracil in Patients With Dihydropyrimidine Dehydrogenase Deficiency Diagnosed With Metastatic Colorectal or Gastroesophageal Cancer
Status: NOT_YET_RECRUITING
Conditions: Metastatic Colorectal Cancer|Metastatic Gastroesophageal Adenocarcinoma|DPD Deficiency
Interventions: DRUG: Lonsurf|DRUG: Oxaliplatin|DRUG: Panitumumab|DRUG: Bevacizumab|DRUG: Trastuzumab|DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized, Multicentre, Open Label, Evaluator Blinded Study to Evaluate Safety and Efficacy of Folitime® of Gemabiotech S.A., Versus Gonal-f ® of Merck Serono, in Patients With Infertility Undergoing ART
Status: COMPLETED
Conditions: Infertility
Interventions: DRUG: FOLITIME®|DRUG: Gonal-F®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Multicenter Study to Evaluate the Efficacy of a 91-Day Extended Cycle Oral Contraceptive for Menstrually-Related Migraine Headaches
Status: COMPLETED
Conditions: Migraine
Interventions: DRUG: 91-day Levonorgestrel Oral Contraceptive|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: AVATAR Anesthesia Alternative in Pediatric Radiotherapy: A Multi-Center Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Anesthesia
Interventions: DEVICE: Audio-Visual Assisted Therapeutic Ambience in Radiotherapy|OTHER: Quality of Life Survey, PedsQL3.0|OTHER: Yale Preoperative Anxiety Scale Short Form (mYPAS-SF)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Oxaliplatin in Treating Patients With Newly Diagnosed Glioblastoma Multiforme
Status: TERMINATED
Conditions: Adult Giant Cell Glioblastoma|Adult Glioblastoma|Adult Gliosarcoma
Interventions: DRUG: oxaliplatin|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Combined Cell Therapy Approach to the Treatment of Neuroblastoma
Status: WITHDRAWN
Conditions: Neuroblastoma|Neoplasms, Nerve Tissue
Interventions: PROCEDURE: Autologous Hematopoietic Progenitor Cell Transplant|BIOLOGICAL: KLH and Tumor Lysate Pulsed DC Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intravitreal Dexamethasone Implant (Ozurdex) Versus Bevacizumab in Patients With Diabetic Macular Edema Undergoing Cataract Surgery
Status: WITHDRAWN
Conditions: Diabetic Macular Edema|Cataract
Interventions: DRUG: Bevacizumab Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Consistency Lots Vaccine Study (V260-009)
Status: COMPLETED
Conditions: Rotavirus Infections
Interventions: BIOLOGICAL: rotavirus vaccine, live, oral, pentavalent|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Varenicline + Prazosin for Heavy Drinking Smokers
Status: COMPLETED
Conditions: Cigarette Smoking|Alcohol Use Disorders
Interventions: DRUG: Varenicline|DRUG: Prazosin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: BurstDR™ micrOdosing stimuLation in De-novo Patients
Status: COMPLETED
Conditions: Pain, Intractable|Pain, Back
Interventions: DEVICE: Stimulation will be delivered at with different microdosing setting to identify the optimal parameter values for each patient.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transurethral Resection Versus Transurethral Enucleation of the Prostate: Prospective Randomized Study
Status: UNKNOWN
Conditions: BPH
Interventions: PROCEDURE: Transurethral resection of the prostate|PROCEDURE: transurethral enucleation of prostate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sargramostim to Prevent Mucositis in Patients Receiving Radiation Therapy for Laryngeal Cancer
Status: COMPLETED
Conditions: Head and Neck Cancer|Oral Complications|Radiation Toxicity
Interventions: BIOLOGICAL: sargramostim|PROCEDURE: quality-of-life assessment|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of Perioperative Lidocaine Intravenous Infusion on Postoperative Recovery After Spine Surgery.
Status: UNKNOWN
Conditions: Spinal Diseases
Interventions: DRUG: Lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Bortezomib and Chemotherapy in Treating Participants With Lymphoid Malignancies Undergoing Stem Cell Transplant
Status: COMPLETED
Conditions: CD20 Positive|Hematopoietic and Lymphoid Cell Neoplasm|Lymphocytic Neoplasm|Lymphoma
Interventions: PROCEDURE: Allogeneic Hematopoietic Stem Cell Transplantation|BIOLOGICAL: Anti-Thymocyte Globulin|DRUG: Bortezomib|DRUG: Carmustine|DRUG: Cytarabine|DRUG: Etoposide|BIOLOGICAL: Filgrastim|DRUG: Melphalan|DRUG: Methotrexate|BIOLOGICAL: Rituximab|DRUG: Tacrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Safety and Efficacy of Tacrolimus Ointment in Treating Chronic Allergic Contact Dermatitis
Status: COMPLETED
Conditions: Dermatitis
Interventions: DRUG: tacrolimus ointment|DRUG: placebo ointment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Interactions Between Telaprevir and Un-boosted Atazanavir
Status: COMPLETED
Conditions: Hepatitis C, Chronic|HIV Infection
Interventions: DRUG: Ritonavir withdrawal, atazanavir 200 mg/12h|DRUG: Telaprevir interactions
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized Controlled Trial of SP-01 (Granisetron Transdermal Delivery System) in Chemotherapy-induced Nausea and Vomiting
Status: COMPLETED
Conditions: Chemotherapy-induced Nausea and Vomiting
Interventions: DRUG: SP-01 (Granisetron Transdermal Delivery System)|DRUG: Granisetron Hydrochloride Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Investigating Train the Trainer Delivery of Mindfulness-based Training
Status: COMPLETED
Conditions: Resilience|Stress
Interventions: BEHAVIORAL: MBAT with proctored practice|BEHAVIORAL: MBAT with non-proctored practice
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE