pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Adaptive-design Dose Finding Study to Assess the Antiviral Efficacy and Safety of NIM811 Administered in Combination With Standard of Care (SOC) in Relapsed Hepatitis C Virus 1 (HCV-1) Infected Patients
Status: COMPLETED
Conditions: Chronic Hepatitis C Genotype-1 Relapse
Interventions: DRUG: NIM811|DRUG: Placebo BID + SOC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Internet Based Emotional Awareness and Expression Therapy for Functional Somatic Disorder With and Without Therapist Support
Status: RECRUITING
Conditions: Functional Somatic Disorder|Somatic Symptom Disorder|Functional Somatic Syndromes
Interventions: BEHAVIORAL: Internet based Emotional Awareness and Expression Therapy (I-EAET)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: DEUX OEUFs: Cracking the Potential of Eggs to Improve Child Growth and Development
Status: RECRUITING
Conditions: Infant Malnutrition|Fetal Growth Retardation
Interventions: DIETARY_SUPPLEMENT: Egg consumption
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Drug-Related Problems in Neonatal Patients
Status: UNKNOWN
Conditions: Neonatal Intensive Care Unit|Medication Errors|Drug-Related Problems|Adverse Drug Event|Drug-Drug Interaction|Clinical Pharmacy|Machine Learning
Interventions: DRUG: Clinical Pharmacist Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Phacoemulsification Combined With Intravitreal Injection of Ranibizumab Prevent Postoperative Capillary Non-perfusion Zone Progress in Non-proliferative Diabetic Retinopathy
Status: UNKNOWN
Conditions: Mild Non-proliferative Diabetic Retinopathy|Cataract Diabetic|Diabetic Retinopathy
Interventions: DRUG: Ranibizumab Injection [Lucentis]|DEVICE: Phacoemulsification
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multiple Organized Systems for Engaging Stroke (MOSES)
Status: WITHDRAWN
Conditions: Stroke (CVA) or TIA
Interventions: BEHAVIORAL: Standard of care, RPM and digital feedback|BEHAVIORAL: Standard of care and RPM only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Antibiotic Prophylaxis for Urinary Catheter Removal After Radical Prostatectomy
Status: TERMINATED
Conditions: Prostate Cancer|Urinary Tract Infection|Clostridium Difficile
Interventions: DRUG: Ciprofloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Taste Profile of Different ALS-008176 Oral Liquid Formulations in Healthy Adult Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Formulation A (ALS-008176)|DRUG: Formulation B (ALS-008176)|DRUG: Formulation C (ALS-008176)|DRUG: Formulation D (ALS-008176)|DRUG: Formulation E (ALS-008176)|DRUG: Formulation F (ALS-008176)|DRUG: Formulation G1 (ALS-008176)|DRUG: Formulation G2 (ALS-008176)|DRUG: Formulation G3 (ALS-008176)|DRUG: Formulation H1 (ALS-008176)|DRUG: Formulation H2 (ALS-008176)|DRUG: Formulation H3 (ALS-008176)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Irofulven in Combination With Oxaliplatin in Patients With Advanced Solid Tumors
Status: COMPLETED
Conditions: Liver Cancer
Interventions: DRUG: Oxaliplatin|DRUG: Irofulven
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 24 Versus 12-Month Dual Antiplatelet Therapy After Drug-Eluting Stent in Patients With Elevated Lipoprotein(a) Levels
Status: NOT_YET_RECRUITING
Conditions: Elevated Lipoprotein(a) Level|Coronary Artery Disease|Drug-Eluting Stent|Dual Antiplatelet Therapy
Interventions: PROCEDURE: 24 Months DAPT|PROCEDURE: 12 Months DAPT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety of Tofacitinib, an Oral Janus Kinase Inhibitor, in Primary Sjogren's Syndrome
Status: RECRUITING
Conditions: Sjogren's Syndrome
Interventions: DRUG: tofacitinib|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy in Treating Patients With Recurrent, Metastatic, or Unresectable Ovarian, Fallopian Tube, or Peritoneal Cancer
Status: COMPLETED
Conditions: Fallopian Tube Cancer|Ovarian Cancer|Primary Peritoneal Cavity Cancer
Interventions: DRUG: exatecan mesylate
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Empagliflozin (BI 10773) in Type 1 Diabetes Mellitus Patients With or Without Renal Hyperfiltration
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: DRUG: BI 10773
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Efficacity and Safety of Oseltamivir and Zanamivir
Status: TERMINATED
Conditions: Gastric Influenza
Interventions: DRUG: oseltamivir + zanamivir|DRUG: oseltamivir + zanamivir's placebo|DRUG: oseltamivir's placebo + zanamivir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: K0706 for Patients Diagnosed With Dementia With Lewy Bodies
Status: RECRUITING
Conditions: Dementia With Lewy Bodies
Interventions: DRUG: Placebo|DRUG: 192 mg powder of K0706|DRUG: 384 mg powder of K0706
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 1/2a Study of BAL101553 as 48-hour Infusions in Patients With Advanced Solid Tumors or Recurrent Glioblastoma
Status: COMPLETED
Conditions: Neoplasms
Interventions: DRUG: BAL101553|DRUG: BAL101553 at MTD
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intensified Chemotherapy in CRC After Resection of Liver Metastases
Status: COMPLETED
Conditions: Colorectal Cancer|Liver Metastases|Chemotherapy
Interventions: DRUG: FOLFIRI|DRUG: FOLFOX-4|DRUG: FOLFIRI-HD|DRUG: FOLFOX-7|DRUG: FOLFIRINOX
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Development and Evaluation of a Cognitive Enhancement Product Made From Selected Thai Herbs for Menopausal Women
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: MP1|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: A Prospective, First in Man Study to Evaluate the Safety and Performance of the NovaCross™ Micro-catheter
Status: COMPLETED
Conditions: Chronic Total Occlusion of Coronary Artery
Interventions: DEVICE: NovaCross, CTO
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Reflux With Sleeve Gastrectomy
Status: ACTIVE_NOT_RECRUITING
Conditions: Reflux Disease, Gastro-Esophageal|Hiatal Hernia|Reflux Esophagitis
Interventions: OTHER: Laparoscopic Sleeve Gastrectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TD-1058 First-In-Human Study in Healthy Subjects and Subjects With Idiopathic Pulmonary Fibrosis
Status: TERMINATED
Conditions: Idiopathic Pulmonary Fibrosis (IPF)
Interventions: DRUG: TD-1058|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Safety of Absorbable and Hem-o-lok Clips in Laparoscopic Cholecystectomy
Status: RECRUITING
Conditions: Laparoscopic Cholecystectomy
Interventions: OTHER: Surgycal procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: EUS-guided Combined Therapy Versus Beta Blocker Therapy in Primary Prophylaxis o GOV II and IGV I
Status: UNKNOWN
Conditions: Gastric Varix|Cirrhosis|GastroIntestinal Bleeding
Interventions: PROCEDURE: Coils + Cyanoacrylate Group + beta-blocker|DRUG: beta blocker therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Vorinostat, Temozolomide, or Bevacizumab in Combination With Radiation Therapy Followed by Bevacizumab and Temozolomide in Young Patients With Newly Diagnosed High-Grade Glioma
Status: COMPLETED
Conditions: Brain Stem Glioma|Cerebral Astrocytoma|Childhood Cerebellar Anaplastic Astrocytoma|Childhood Cerebral Anaplastic Astrocytoma|Childhood Spinal Cord Neoplasm
Interventions: BIOLOGICAL: Bevacizumab|DRUG: Temozolomide|DRUG: Vorinostat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lp(a) Lowering Study of Pelacarsen (TQJ230) in US Black/African American and Hispanic Participants With Elevated Lp(a) and Established ASCVD
Status: RECRUITING
Conditions: Elevated Lp(a) and Established Atherosclerotic Cardiovascular Disease
Interventions: DRUG: TQJ230|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Precise Treatment for BLIS Subtype of TNBC in the First-line Treatment of Locally Advanced or Metastatic Breast Cancer
Status: RECRUITING
Conditions: Triple-Negative Breast Cancer
Interventions: DRUG: VEGFR and nab-paclitaxel, with maintenance of VEGFR and capecitabine|DRUG: nab-paclitaxel, with maintenance of capecitabine|DRUG: Eribulin Mesylate/Vinorelbine/Capecitabine/Carboplatin/UTD1|DRUG: VEGFR and TPC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Fibrin Sealant to Reduce the Amount of Post-thyroidectomy Drain
Status: COMPLETED
Conditions: Thyroid Carcinoma|Thyroidectomy
Interventions: DRUG: Usage of Fibrin sealant|PROCEDURE: Thyroidectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Identification of Cerebrospinal Fluid With Injeq IQ-Needle During Paediatric Lumbar Puncture
Status: COMPLETED
Conditions: Pediatric Lumbar Puncture
Interventions: DEVICE: Injeq IQ-Needle
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: QOL, ADL and Pain Before and After Intervention With N3 From Krill With D3.
Status: UNKNOWN
Conditions: Quality of Life|Pain
Interventions: DIETARY_SUPPLEMENT: Omega Krill with D3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Monitor the Safety and Reactogenicity of Fluarix™ in Korean Subjects Aged > 6 Months of Age.
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: FluarixTM
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Assessing Moral Cognitive Skills in Adults With Autism Spectrum Disorders
Status: RECRUITING
Conditions: Autism Spectrum Disorder
Interventions: OTHER: Neuropsychological assessments (tests allowing to measures attentional, executive and emotional performances) and experimental protocol assessing moral cognition
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Juice Plus Supplement Clinical Trial
Status: UNKNOWN
Conditions: Cognitive Impairment|Alzheimer Disease, Early Onset|Mild Cognitive Impairment
Interventions: DIETARY_SUPPLEMENT: Juice Plus+
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Prevalence of Peripheral Neuropathy Among Patients With Auditory Neuropathy
Status: RECRUITING
Conditions: Auditory Neuropathy Spectrum Disorder,, Peripheral Neuropathy
Interventions: DIAGNOSTIC_TEST: Pure tone audiometry PTA ,Speech audiometry ,Otoacoustic emission,Auditory evoked potentials including (ABR).
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Ultrasound Guided Subcostal Transversus Abdominis Plane Block Versus Quadratus Lumborum Block for Pediatrics Undergoing Pyeloplasty.
Status: COMPLETED
Conditions: Pain Management|Pediatrics|Anesthesia
Interventions: DRUG: Bupivacaine Hydrochloride 0.25% Injection Solution [MARCAINE]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: DAS181 for Patients With Severe Hospitalized Flu and SAD-RVs (COVID-19)
Status: UNKNOWN
Conditions: Influenza Infection|SAD-RV Infection and COVID-19
Interventions: DRUG: DAS181|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cultural Pride Reinforcement for Early School Readiness
Status: COMPLETED
Conditions: School Readiness|Racial Socialization|Child Development
Interventions: BEHAVIORAL: Cultural Pride Reinforcement for Early School Readiness (CPR4ESR)|BEHAVIORAL: Reach Out and Read (ROR)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Evaluating the Effect of Intravenous Dexamethasone on the Duration of Spinal Anesthesia After Cesarean Delivery
Status: RECRUITING
Conditions: Spinal Anesthesia|Dexamethasone
Interventions: DRUG: Dexamethasone|DRUG: Metoclopramide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Favipiravir vs Hydroxychloroquine vs Control in COVID -19
Status: COMPLETED
Conditions: SARS-CoV 2|COVID-19
Interventions: DRUG: Hydroxychloroquine|DRUG: Favipiravir|OTHER: Routine care for COVID-19 patients
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Astaxanthin Supplementation
Status: COMPLETED
Conditions: Dietary Supplements
Interventions: OTHER: Astaxanthin (12 mg/day) intervention|OTHER: 36 mg/day astaxanthin intervention|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Ramosetron on Late PONV (Postoperative Nausea and Vomiting)
Status: COMPLETED
Conditions: Postoperative Nausea and Vomiting|Breast Cancer Female
Interventions: DRUG: Ramosetron Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Psychological Risk Factors for Functional Somatic Disorders
Status: COMPLETED
Conditions: Irritable Bowel Syndrome|Fibromyalgia|Chronic Fatigue Syndrome|Somatoform Disorders|Bodily Distress Syndrome|Medically Unexplained Symptoms|Medically Unexplained Syndrome
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study to Assess the Safety, Tolerability, and Pharmacodynamic (PD) Effects of FRM-0334 in Subjects With Prodromal to Moderate Frontotemporal Dementia With Granulin Mutation
Status: UNKNOWN
Conditions: Granulin Mutation
Interventions: DRUG: FRM-0334|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Single Rising Dose Study of MK-8723 in Healthy Participants and Participants With Immune Thrombocytopenia Purpura (MK-8723-001)
Status: COMPLETED
Conditions: Immune Thrombocytopenia Purpura
Interventions: DRUG: MK-8723|DRUG: Matching Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Arrhythmias in Pulmonary Hypertension Assessed by Continuous Long-term Cardiac Monitoring
Status: RECRUITING
Conditions: Pulmonary Hypertension|Arrhythmias, Cardiac|Heart Rate Variability|Risk Assessment
Interventions: DEVICE: Loop recorder implantation|DEVICE: A smartwatch
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Intensive Referral to Al-Anon: Benefits to Concerned Others and Their Drinkers
Status: COMPLETED
Conditions: Alcohol Use Disorder
Interventions: BEHAVIORAL: Al-Anon Intensive Referral (AIR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: RCT of TAE Simultaneously Combined Thermal Ablation for Large Hepatocellular Carcinoma
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma, Adult
Interventions: DRUG: Chemotherapy drug|DRUG: Embolic agents|PROCEDURE: Simultaneously|PROCEDURE: Sequentially|DEVICE: Ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radiofrequency Ablation With Gradual Radiofrequency Energy Increment for Hepatocellular Carcinoma Treatment
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma|Liver Cirrhosis|Chronic Liver Disease
Interventions: PROCEDURE: Radiofrequency ablation using gradual radiofrequency energy delivery with Octopus electrodes
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sleep and Healthy Aging Research for Depression (SHARE-D) Study
Status: COMPLETED
Conditions: Depression in Old Age
Interventions: BIOLOGICAL: Endotoxin|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Study of Pembrolizumab With or Without CC-486 in Patients With Platinum-resistant Ovarian Cancer
Status: TERMINATED
Conditions: Epithelial Ovarian Cancer
Interventions: DRUG: CC-486|BIOLOGICAL: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mediterranean Diet and Nutritional Support in Heart Failure Sarcopenia
Status: ACTIVE_NOT_RECRUITING
Conditions: Sarcopenia
Interventions: DIETARY_SUPPLEMENT: Hypercaloric, hyperproteic oral supplement|OTHER: Mediterranean diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of the Performance of Direct Portal Pressure Measurement by Endoscopic Ultrasound in a Large Cohort of Patients With Advanced Chronic Liver Disease of Different Etiologies and Newly Diagnosed Clinically Significant Portal Hypertension (EVADIPP)
Status: RECRUITING
Conditions: Portal Hypertension
Interventions: DEVICE: EUS PPG measurement
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety, Reactogenicity, Immunogenicity, and Efficacy of Quadrivalent Inactivated Subunit Influenza Vaccine Grippol® Quadri and Trivalent Inactivated Polymer-Subunit Vaccine Grippol® Plus in Volunteers
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Grippol® Quadri|BIOLOGICAL: Grippol® Plus, trivalent (Yamagata lineage)|BIOLOGICAL: Grippol® Plus, trivalent (Victoria lineage)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Synbiotic Supplementation in Cyclists
Status: ACTIVE_NOT_RECRUITING
Conditions: Exercise Endurance
Interventions: DIETARY_SUPPLEMENT: Synbiotic|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Catheter Ablation of All Inducible AT Post AF Ablation
Status: COMPLETED
Conditions: Atrial Tachycardia|Atrial Fibrillation
Interventions: PROCEDURE: AT case 1.1|PROCEDURE: AT case 2.1|PROCEDURE: AT case 1.2|PROCEDURE: AT case 1.3|PROCEDURE: AT case 1.4|PROCEDURE: AT case 2.2|PROCEDURE: AT case 2.3|PROCEDURE: AT case 2.4|PROCEDURE: SR Case 1|PROCEDURE: SR Case 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Simplified Lung Ultrasound Guided Management Protocol Of Pulmonary Congestion in Hemodialysis
Status: RECRUITING
Conditions: End Stage Renal Disease
Interventions: OTHER: Intervention Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Evaluation of Diaphragmatic Function and Quadriceps Muscle Thickness in Patients Receiving High Protein Nutrition
Status: NOT_YET_RECRUITING
Conditions: ICU Acquired Weakness
Interventions: OTHER: patients who will receive 2 gm protein/kg/day will be evaluated by ultrasound for diaphragmatic function and quadriceps muscle thickness
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Hydrogen-oxygen Mixed Gas in the Treatment of Insomnia
Status: ENROLLING_BY_INVITATION
Conditions: Insomnia
Interventions: DEVICE: Hydrogen-oxygen mixed gas(H2-O2) inhalation|DEVICE: Air inhalation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: RESveratrol To Improve Outcomes in oldeR pEople With PAD (the RESTORE Trial)
Status: COMPLETED
Conditions: Peripheral Arterial Disease
Interventions: DRUG: Resveratrol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Influence of Treatment With Olanzapine or Ziprasidone on Transcapillary Glucose Transport in Human Skeletal Muscle
Status: COMPLETED
Conditions: Healthy Male Volunteers
Interventions: DRUG: ziprasidone or olanzapine|PROCEDURE: hyperinsulinaemic euglycaemic clamp|PROCEDURE: microdialysis (skeletal muscle)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: A Study in Healthy Japanese and Chinese Men to Test How Well Different Doses of BI 706321 Are Tolerated
Status: TERMINATED
Conditions: Healthy
Interventions: DRUG: BI 706321|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Livelihoods Intervention With Urban Refugee Youth in Kampala, Uganda
Status: RECRUITING
Conditions: Financial Stress|Social Functioning|Social Skills
Interventions: DIAGNOSTIC_TEST: HIVST|DEVICE: mHealth|BEHAVIORAL: Creating Futures Livelihoods program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Evaluation of Diabetes and WELLbeing Programme
Status: COMPLETED
Conditions: Type 2 Diabetes|Type 2 Diabetes Treated With Insulin
Interventions: BEHAVIORAL: DWELL (Diabetes and WELLbeing) Programme
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Percutaneous Nephrostomy Versus Stent In Sepsis Trial
Status: WITHDRAWN
Conditions: Ureteric Calculus|Sepsis|Hydronephrosis
Interventions: PROCEDURE: Percutaneous nephrostomy|PROCEDURE: Retrograde ureteric JJ stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Celecoxib Versus Naproxen for Prevention of Recurrent Ulcer Bleeding in Arthritis Patients
Status: COMPLETED
Conditions: Arthritis|Cardiovascular Diseases|Cerebrovascular Disorders
Interventions: DRUG: Celecoxib(drug)|DRUG: Naproxen(drug)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: BEP Targeting Strategies in Ethiopia
Status: RECRUITING
Conditions: Small for Gestational Age at Delivery|Gestational Weight Gain|Stillbirth|Preterm Birth|Birth Weight|Maternal Anemia in Pregnancy, Before Birth|Neonatal Death|Perinatal Death
Interventions: DIETARY_SUPPLEMENT: Targeted BEP based on baseline nutritional status|DIETARY_SUPPLEMENT: Targeted BEP based on baseline nutritional status and monthly GWG monitoring|DIETARY_SUPPLEMENT: Universal BEP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety, Tolerability and Pharmacokinetics of the Fixed Dose Combination of BI 1744 CL Plus BI 54903 XX Via Respimat® B Versus the Free Combination of BI 1744 CL Via Respimat® A and BI 54903 XX Via Respimat® B in Healthy Male and Female Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BI 1744 CL|DRUG: BI 54903 XX|DRUG: BI 1744 CL + BI 54903 XX FDC|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Hunting for the Off-Target Properties of Ticagrelor on Endothelial Function in Humans (HI-TECH)
Status: COMPLETED
Conditions: Cardiovascular Diseases
Interventions: DRUG: Ticagrelor|DRUG: Prasugrel|DRUG: Clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Efficacy of ISIS-GCGRRx in Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: ISIS-GCGRRx - Dose Level 1|DRUG: ISIS-GCGRRx - Dose Level 2|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase III Multicentre Trial of Oral Mesalazine in Patients With Mild to Moderate Ulcerative Colitis.
Status: NOT_YET_RECRUITING
Conditions: Colitis, Ulcerative
Interventions: DRUG: Mesalazine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Introduction of Fish Early in the Complementary Feeding Period to Improve Infant Growth
Status: COMPLETED
Conditions: Infant Growth
Interventions: DIETARY_SUPPLEMENT: Fish Powder|DIETARY_SUPPLEMENT: Sorghum powder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SALT for Unresectable Colorectal Liver Metastases
Status: NOT_YET_RECRUITING
Conditions: Colon Cancer Liver Metastases
Interventions: PROCEDURE: sequential adult left lateral lobe liver transplantation (SALT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Short-term Effects of the Simultaneous Use of Two Physiotherapeutic Methods in the Treatment of Adolescent Idiopathic Scoliosis - Pilot Study
Status: COMPLETED
Conditions: The Spirometry;|The Strength of Respiratory Muscles - MIP, MEP;|Kyphosis (Plurimeter-V)|The Angle of Trunk Rotation in Thoracic Part
Interventions: OTHER: Derotational manual therapy techniques in selected segments in spine|BEHAVIORAL: Sham therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Haploidentical Allogeneic Peripheral Blood Transplantation: Examining Checkpoint Immune Regulators' Expression
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Myeloid Leukemia|Chronic Lymphocytic Leukemia|Chronic Myeloid Leukemia|Myelodysplasia|Myeloproliferative Disorder|Myelofibrosis|Lymphoma|Lymphoma, Non-Hodgkin|Plasma Cell Disorder
Interventions: DRUG: Cyclophosphamide|DRUG: Fludarabine|RADIATION: Total Body Irradiation|DRUG: Tacrolimus|DRUG: cellcept|DRUG: g-csf|PROCEDURE: Peripheral Blood Transplant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Topical Dermaprazole for Radiation Dermatitis in Breast Cancer and Head and Neck Cancer Patients (TOPAZ)
Status: RECRUITING
Conditions: Radiation Dermatitis|Breast Cancer|Head and Neck Cancer
Interventions: DRUG: Dermaprazole 1%|DRUG: Dermaprazole 2%
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Novel Splinting Technique Using 3D Models
Status: UNKNOWN
Conditions: Arthritis|Osteoarthritis Hand|Scleroderma, Systemic|Scleroderma, Diffuse|Rheumatoid Arthritis
Interventions: OTHER: Custom Fabricated Splint
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Metformin Use on Mortality in Diabetic and Non Diabetic Patients With Sepsis and Septic Shock.
Status: NOT_YET_RECRUITING
Conditions: Septic Shock
Interventions: DRUG: Metformin|OTHER: standardized protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Phase Ib/II Clinical Study of Pexa-Vec (Vaccinia GM CSF / Thymidine Kinase-Deactivated Virus) Combined With Recombinant Whole Human Anti-PD-L1 Monoclonal Antibody (ZKAB001) in Metastatic Melanoma
Status: UNKNOWN
Conditions: Local Progression or Metastatic Melanoma With Failed First-line Treatment
Interventions: BIOLOGICAL: Pexa-Vec combined with ZKAB001|BIOLOGICAL: ZKAB001 monotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Analysis of Human Knee Joint Fluid Using Metabonomic, Genomic and Tribology Techniques
Status: UNKNOWN
Conditions: Osteoarthritis|Septic Arthritis|Rheumatoid Arthritis
Interventions: PROCEDURE: Intra-articular aspiration of Joint|PROCEDURE: Joint irrigation washout|PROCEDURE: Total Joint Arthroplasty|PROCEDURE: Revision Joint Arthroplasty
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Role of Alphacalcidol Supplement to Reduce Pain and COMP in Geriatric Knee Osteoarthritis Patients
Status: COMPLETED
Conditions: Osteoarthritis, Knee|Aged
Interventions: DRUG: Alfacalcidol 1 MCG Oral Capsule|DRUG: Sugar pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 2a Study Evaluating the Arsenic Trioxide (ATO) in Systemic Lupus (SLE) (Protocol LUPSENIC)
Status: TERMINATED
Conditions: Systemic Lupus
Interventions: DRUG: Arsenic trioxide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Aumolertinib in Patients With AI-diagnosed EGFR-mutant High-risk Pulmonary Ground-glass Opacity.
Status: RECRUITING
Conditions: Lung Cancer
Interventions: DRUG: Aumolertinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ACtive Children Enhance LEaRning and AttenTION: A Randomized Controlled Trial (RCT)
Status: COMPLETED
Conditions: Physical Inactivity
Interventions: BEHAVIORAL: ACtive Children Enhance LEaRning and AttenTION (ACCELERATION)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Learn How Safe and Effective Risankizumab is When Compared to Deucravacitinib to Treat Participants With Moderate Plaque Psoriasis and Who Need to Try Systemic Treatment (Works Throughout the Whole Body)
Status: RECRUITING
Conditions: Moderate Plaque Psoriasis
Interventions: DRUG: Risankizumab|DRUG: Deucravacitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy Plus Radiation Therapy in Treating Patients With Stage III Non-small Cell Lung Cancer That Cannot Be Surgically Removed
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DRUG: cisplatin|DRUG: gemcitabine hydrochloride|DRUG: paclitaxel|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Photobiomodulation in Oral Lichen Planus
Status: UNKNOWN
Conditions: Lichen Planus, Oral|Low-Level Light Therapy
Interventions: DRUG: Propionate clobetasol gel 0.05%|DEVICE: Photobiomodulation|OTHER: Placebo gel|OTHER: Placebo Photobiomodulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Experimental Study to Determine the Effects of Human Refluxate on Macrophage Phenotype and Its Correlation With GERD
Status: COMPLETED
Conditions: Gastroesophageal Reflux Disease (GERD)
Interventions: PROCEDURE: Upper gastrointestinal endoscopy with biopsy and collection of refluxate|PROCEDURE: Esophageal high-resolution manometry and 24-h esophageal pH-impedance monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Phase 2 Tolerability and Effects of ALK-001 on Stargardt Disease
Status: RECRUITING
Conditions: Stargardt Disease|Stargardt Macular Degeneration|Stargardt Macular Dystrophy|Autosomal Recessive Stargardt Disease 1 (ABCA4-related)
Interventions: DRUG: ALK-001|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: LUX-Lung 7: A Phase IIb Trial of Afatinib(BIBW2992) Versus Gefitinib for the Treatment of 1st Line EGFR Mutation Positive Adenocarcinoma of the Lung
Status: COMPLETED
Conditions: Lung Neoplasms
Interventions: DRUG: Afatinib|DRUG: gefitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Allogenic Umbilical Cord Blood and Erythropoietin Combination Therapy for Cerebral Palsy
Status: COMPLETED
Conditions: Cerebral Palsy
Interventions: BIOLOGICAL: Umbilical Cord Blood Infusion|DRUG: Erythropoietin Injection|OTHER: Active Rehabilitation|OTHER: Placebo Umbilical Cord Blood|OTHER: Placebo Erythropoietin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study in Healthy Adult Male Participants to Gather Information How the Human Body Absorbs, Distributes and Excretes the Study Drug Selitrectinib Including the Effect of the Interaction of Food With the Study Drug on the Human Body
Status: COMPLETED
Conditions: Solid Tumors Harboring NTRK Fusion
Interventions: DRUG: Selitrectinib (BAY2731954)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Intra-corporeal vs Extra-corporeal Anastomosis in Laparoscopically Assisted Right Hemicolectomy
Status: COMPLETED
Conditions: Pain
Interventions: PROCEDURE: Intracorporeal anastomosis.|PROCEDURE: Extracorporeal anastomosis|DEVICE: Echelon Endopatch|DEVICE: Proximate Linear Cutter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Blinatumomab for MRD in Pre-B ALL Patients Following Stem Cell Transplant
Status: TERMINATED
Conditions: B-cell Adult Acute Lymphoblastic Leukemia|Stem Cell Leukemia|Minimal Residual Disease
Interventions: BIOLOGICAL: blinatumomab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Local Anesthetic and Ozone Injection in Patients With Myofascial Pain Syndrome
Status: UNKNOWN
Conditions: Myofascial Pain Syndrome|Ozone
Interventions: DRUG: Lidocaine 2% Injectable Solution|DRUG: Ozone|OTHER: stretching exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study of Ketogenic Diet and Metformin in Glioblastoma: Feasibility and Metabolic Imaging
Status: RECRUITING
Conditions: Glioblastoma
Interventions: OTHER: Ketogenic Diet|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pembrolizumab, Ixazomib Citrate, and Dexamethasone in Treating Patients With Relapsed Multiple Myeloma
Status: COMPLETED
Conditions: Recurrent Plasma Cell Myeloma
Interventions: DRUG: Dexamethasone|DRUG: Ixazomib Citrate|OTHER: Laboratory Biomarker Analysis|BIOLOGICAL: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: This is a Phase 1 Study of Eribulin Mesylate in Pediatric Participants With Recurrent or Refractory Solid Tumors (Excluding [Central Nervous System] CNS), Including Lymphomas
Status: COMPLETED
Conditions: Pediatrics|Solid Tumors
Interventions: DRUG: Eribulin Mesylate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intrastromal Fresh Human Corneal Lenticule Implantation Using Smile Surgery for Treatment of Irregular Corneal Astigmatism After Penetrating Keratoplasty (New Approach)
Status: ACTIVE_NOT_RECRUITING
Conditions: Irregular Astigmatism
Interventions: DEVICE: Intrastromal Fresh Human Lenticule Implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Facebook Intervention for Young Sexual and Gender Minority Smokers
Status: COMPLETED
Conditions: Tobacco Use|Smoking|Tobacco Dependence|Tobacco Use Disorder|Tobacco Use Cessation|Tobacco Smoking|Smoking Cessation|Smoking, Cigarette|Smoking, Tobacco
Interventions: BEHAVIORAL: POP:|BEHAVIORAL: TSP:
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimal Lesion Preparation With Non-compliant Balloons Before Implantation Of Bioresorbable Scaffolds (OPreNBiS)
Status: UNKNOWN
Conditions: Coronary Artery Disease|Angina|Unstable Angina|Stable Angina
Interventions: DEVICE: Predilatation with OPN NC balloon catheter.|DEVICE: Predilatation with standard compliant balloon.|DEVICE: Absorb BVS implantation.|PROCEDURE: Treated segment visualization by OCT.|OTHER: Clinical FU at 12 months.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Admission to Kangaroo Mother Care (KMC) Ward and Maternal Postpartum Depression
Status: NOT_YET_RECRUITING
Conditions: Low Birth Weight|Kangaroo Mother Care|Postpartum Depression|Neurodevelopmental Outcome|Pre-Term
Interventions: BEHAVIORAL: Kangaroo mother care (KMC) support for > 2 days|BEHAVIORAL: Kangaroo mother care (KMC) support for < 2 days
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Possible Efficacy and Safety of Mebendazole in Patients With Ulcerative Colitis Treated With Mesalamine
Status: NOT_YET_RECRUITING
Conditions: Ulcerative Colitis
Interventions: DRUG: Mebendazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Extension Study of AK002 in Patients With Eosinophilic Gastritis and/or Eosinophilic Duodenitis
Status: COMPLETED
Conditions: Eosinophilic Gastritis|Eosinophilic Gastroenteritis|Eosinophilic Duodenitis
Interventions: DRUG: AK002
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Invasive Diagnostic and Therapeutic Management of Cerebral Vasospasm After Aneurysmatic Subarachnoid Hemorrhage
Status: UNKNOWN
Conditions: Cerebral Vasospasm After Subarachnoid Hemorrhage
Interventions: OTHER: Combination of TBA and intraarterial application of vasodilators
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Stability of Revision Total Hip Arthroplasty Implants Using Radiostereometric Analysis
Status: WITHDRAWN
Conditions: Osteoarthritis of Hip|Failure of Primary THA
Interventions: PROCEDURE: Bead placement during revision hip replacement surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Single Ascending Dose Pharmacology Study of Anaprazole in Healthy Chinese Subjects
Status: COMPLETED
Conditions: Healthy Male Volunteers
Interventions: DRUG: Anaprazole Sodium|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability of Namisol in the Elderly
Status: COMPLETED
Conditions: Drug Safety
Interventions: DRUG: delta-9-tetrahydrocannabinol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pre-sleep Macros on Sleep Quality and Recovery
Status: ENROLLING_BY_INVITATION
Conditions: Sleep
Interventions: DIETARY_SUPPLEMENT: Casein protein|DIETARY_SUPPLEMENT: a-lactalbumin protein|DIETARY_SUPPLEMENT: Carbohydrate|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Tandem VR: Synchronized Nature-Based Experiences in Virtual Reality for Hospice Patients and Their Caregivers
Status: RECRUITING
Conditions: Hospice|End of Life|Palliative Care|Pain|Anxiety|Fear of Death
Interventions: DEVICE: Tandem Virtual Reality
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open-label Study of WVE-N531 in Patients With Duchenne Muscular Dystrophy (FORWARD-53)
Status: ACTIVE_NOT_RECRUITING
Conditions: Duchenne Muscular Dystrophy
Interventions: DRUG: WVE-N531
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GAG Replacement vs URethral DIlAtatioN
Status: WITHDRAWN
Conditions: Recurrent Urinary Tract Infection
Interventions: PROCEDURE: Rigid cystoscopy with urethral dilatation|PROCEDURE: Flexible cystoscopy and installation of Glycosaminoglycan layer replacement (laluril)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dexmedetomidine and Neuroprotection in Children Undergoing General Anesthesia
Status: COMPLETED
Conditions: Dexmedetomidine
Interventions: DRUG: Dexmedetomidine Hydrochloride|OTHER: control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Clinical Study of Nemtabrutinib in Japanese Participants With Hematological Malignancies (MK-1026-002)
Status: ACTIVE_NOT_RECRUITING
Conditions: Mature B-cell Neoplasms
Interventions: DRUG: Nemtabrutinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Retinoid 9cUAB30 in Preventing Cancer in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Subject
Interventions: OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacological Study|OTHER: Placebo|DRUG: Retinoid 9cUAB30
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of Ultrasound and X-ray as Screening Tests for Diagnosis of Lower Extremity Stress Fracture.
Status: UNKNOWN
Conditions: Stress Fracture|Ultrasound Therapy|Musculoskeletal Ultrasound
Interventions: DIAGNOSTIC_TEST: Diagnostic Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING