pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Effects of Arm Cycling and Leg Cycling on Postprandial Blood Glucose Levels in Healthy Persons
Status: TERMINATED
Conditions: Hyperglycemia, Postprandial
Interventions: BEHAVIORAL: Arm Cycling|BEHAVIORAL: Leg Cycling|BEHAVIORAL: Sitting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dental Plaque Removal Ability of Prototype Power Toothbrush Versus a Manual Toothbrush in Healthy Participants
Status: COMPLETED
Conditions: Dental Plaque
Interventions: DEVICE: Reference MTB|DEVICE: Reference PTB|DEVICE: Prototype PTB (Gum line mode)|DEVICE: Prototype PTB (Combined mode)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Prehabilitation of Patients With oEsophageal Malignancy Undergoing Peri-operative Treatment
Status: UNKNOWN
Conditions: Oesophageal Adenocarcinoma|Chemotherapy Effect|Surgery
Interventions: BEHAVIORAL: Exercise prehabilitation during chemotherapy before surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Prospective Trial Comparing Intravesical Chondroitin Sulphate 2% and DMSO in the Treatment of PBS/Interstitial Cystitis
Status: TERMINATED
Conditions: Painful Bladder Syndrome|Interstitial Cystitis
Interventions: PROCEDURE: Bladder instillations
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intervetional Lay Open and Curettage Versus Endoscopic (E.P.Si.T) Method in the Treatment of Sacrococcygeal Pilonidal Sinus Disease
Status: UNKNOWN
Conditions: Endoscopic Pilonidal Sinus
Interventions: PROCEDURE: Lay open and curettage|PROCEDURE: Endoscopic (E.P.Si.T) method
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Capecitabine as Radiosensitising Agent in Neoadjuvant Treatment of Locally Advanced Resectable Rectal Cancer
Status: COMPLETED
Conditions: Resectable Rectal Cancer Clinical Stage II and III
Interventions: DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Safety and Activity of an Anti-PDL1 Antibody (DURVALUMAB) Combined With CSF-1R TKI (PEXIDARTINIB) in Patients With Metastatic/Advanced Pancreatic or Colorectal Cancers
Status: COMPLETED
Conditions: Colorectal Cancer|Pancreatic Cancer|Metastatic Cancer|Advanced Cancer
Interventions: DRUG: Pexidartinib|DRUG: Durvalumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Efficacy and Tolerability of Intravitreal Injections of Ranibizumab Compared to Intravitreal Injections of Ranibizumab Combined With Targeted Retinal Photocoagulation to Treat Radiation Retinopathy.
Status: COMPLETED
Conditions: Radiation Retinopathy
Interventions: DRUG: 0.5 mg ranibizumab|PROCEDURE: Targeted Retinal Photocoagulation (TRP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Applicability and Safety of Vibration Therapy in Intensive Care Unit (ICU) Patients
Status: COMPLETED
Conditions: Respiratory Failure|Sepsis|Brain Injury
Interventions: DEVICE: ProMedVi Vibrosphere|DEVICE: schwa-medico MUSKELaktiv|DEVICE: Galileo Home Plus (ICU)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Does Soluble Fiber Supplementation Result in Lower Postprandial Blood Glucose in Women With Gestational Diabetes Compared With no Supplementation After a Standardized Breakfast?
Status: RECRUITING
Conditions: Gestational Diabetes
Interventions: DIETARY_SUPPLEMENT: Supplementation with soluble fibre from guar (Optifibre©)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Community Health Workers and mHealth for Sickle Cell Disease Care
Status: ACTIVE_NOT_RECRUITING
Conditions: Sickle Cell Disease
Interventions: OTHER: Peer Community Health Worker|OTHER: Mobile Health
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy and Safety Study of CC-292 Versus Placebo as Co-therapy With Methotrexate in Active Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: CC-292|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Non - Surgical Periodontal Therapy in Diabetic Patients.
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Periodontal Diseases
Interventions: PROCEDURE: Non-surgical periodontal treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clazakizumab for the Treatment of Chronic Active Antibody Mediated Rejection in Kidney Transplant Recipients
Status: TERMINATED
Conditions: Antibody-mediated Rejection
Interventions: BIOLOGICAL: Clazakizumab|DRUG: Physiologic saline solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of TLL-018 Extended and Immediate Release Formulation for Bioequivalence Testing in Healthy Chinese Subjects
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: TLL-018 extended-release tablet|DRUG: TLL-018 immediate-release tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Development and Validation of a Fast, Semi-Automated Hybrid Imaging Platform to Assess Coronary Atherosclerotic Plaque Morphology, Endothelial Shear Stress and Arterial Inflammation: A Proof of Principle Study (VALID-PET-CT)
Status: UNKNOWN
Conditions: Stable Angina|Coronary Artery Disease
Interventions: DIAGNOSTIC_TEST: PET-CT
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Blood Loss and Complications of Internal Fixation of Femoral Neck Fractures in Patients Treated With Clopidogrel
Status: UNKNOWN
Conditions: Femoral Neck Fractures|Pertrochanteric Fractures|Antiaggregant Therapy
Interventions: PROCEDURE: clopidogrel|PROCEDURE: no antiaggregant therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Remission-induction Regimen With Infliximab for Severe Extrathoracic Sarcoidosis (EFIRTES)
Status: COMPLETED
Conditions: Extrathoracic Sarcoidosis
Interventions: DRUG: Infliximab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Adult Polysomnography Primary Insomnia Cross Over Study (0928-049)(TERMINATED)
Status: TERMINATED
Conditions: Primary Insomnia
Interventions: DRUG: MK0928 / Duration of Treatment : 8 Weeks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, Pharmacokinetics, and Immunoregulatory Study of Urelumab (BMS-663513) in Subjects With Advanced and/or Metastatic Solid Tumors and Relapsed/Refractory B-cell Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Cancer - Solid Tumors and B-Cell Non-Hodgkin's Lymphoma
Interventions: DRUG: Urelumab (BMS-663513)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Pregabalin on Post Operative Pain in Abdominal Hysterectomy Under Spinal Anesthesia With Intrathecal Morphine
Status: COMPLETED
Conditions: Post Operative Pain
Interventions: DRUG: placebo|DRUG: Pregabalin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Mobilization Protocol Assisted With Simulated Clinical Immersion Videos on Patients Undergoing Lumbar Spine Surgery
Status: COMPLETED
Conditions: Lumbar Spine Surgery|Lumbar Disc Herniation
Interventions: OTHER: Mobilization Protocol Assisted with Simulated Clinical Immersion Videos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Dose-Ranging Efficacy Study of Topical NEOSH101 to Treat Male Pattern Hair Loss
Status: UNKNOWN
Conditions: Androgenetic Alopecia
Interventions: DRUG: tetrapeptide aldehyde proteasome inhibitor (NEOSH101)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study to Determine if Raltegravir Eradicates HIV From Peripheral Blood Mononuclear Cells
Status: WITHDRAWN
Conditions: HIV Infections|Acquired Immune Deficiency Syndrome
Interventions: DRUG: Raltegravir plus Truvada|DRUG: Atripla
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Exploratory Study Examining The Effects Of Taking GW679769 Once-Daily For 4 Days In Patients With Functional Dyspepsia
Status: COMPLETED
Conditions: Nonulcer Dyspepsia
Interventions: DRUG: GW679769 oral tablets|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Randomized Controlled Trial of the New Method of Selective Coronary Vein Bypass Graft (SCVBG)
Status: UNKNOWN
Conditions: Coronary Atherosclerotic Heart Disease
Interventions: PROCEDURE: A method of operation: LIMA-GSV-SCVBG|PROCEDURE: BIMA-SCVBG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess Safety, Pharmacokinetics, and Pharmacodynamics of mRNA-3705 in Participants With Isolated Methylmalonic Acidemia
Status: RECRUITING
Conditions: Methylmalonic Acidemia
Interventions: BIOLOGICAL: mRNA-3705
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Peer-led Implementation of TB-HIV Education and Adherence Counseling in Uganda
Status: NOT_YET_RECRUITING
Conditions: Tuberculosis|HIV
Interventions: BEHAVIORAL: Standard TB-EC|BEHAVIORAL: Peer navigation strategy for TB-EC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Telephone Intervention in Patients With Acute Coronary Syndrome (ACS) and Diabetes
Status: TERMINATED
Conditions: Type 2 Diabetes Mellitus|Acute Coronary Syndrome
Interventions: BEHAVIORAL: telephone contact
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Electrical Stimulation in Patients With Prolonged Mechanical Ventilation
Status: COMPLETED
Conditions: Respiratory Failure
Interventions: OTHER: electrical stimulation (high frequency)|OTHER: electrical stimulation (low frequency)|OTHER: sham group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Gait Training for Individuals With Paraplegia Using the H-MEX Exoskeleton
Status: UNKNOWN
Conditions: Spinal Cord Injuries|Paraplegia
Interventions: DEVICE: Gait training using H-MEX exoskeleton
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Ethanol-induced Vestibular Dysfunction as a Model for Bilateral Vestibular Syndrome.
Status: UNKNOWN
Conditions: vHIT- and VOG-model for Bilateral Vestibular Neuronitis
Interventions: OTHER: Ethanol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Intestinal Dysbiosis During Obstructive Sleep Apnea Syndrome
Status: WITHDRAWN
Conditions: Obstructive Sleep Apnea Syndrome|Gut Microbiota
Interventions: DEVICE: CPAP or nasal dilators
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Custom-Made Zirconia Crowns and 3D-Printed Resin Crowns Versus Ready-Made Zirconia Crowns in Primary Molars
Status: RECRUITING
Conditions: Dental Crowns
Interventions: PROCEDURE: esthetic dental crowns|PROCEDURE: control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pressure Ulcers in Patients Receiving Enteral Nutrition Therapy and Their Relationship With Gut Microbiota
Status: UNKNOWN
Conditions: Malnutrition|Pressure Ulcer
Interventions: DIETARY_SUPPLEMENT: symbiotic|DIETARY_SUPPLEMENT: zinc and arginine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Decreasing Risk of Coronary Artery Disease in Schizophrenia by Omega-3 Fatty Acid Supplementation
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder|Major Depression|Bipolar Disorder|Coronary Artery Disease
Interventions: DRUG: Eicosapentaenoic acid (omega-3 fatty acid)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Tachosil® for Prevention of Hemorrhage After Loop Electrosurgical Excisional Procedure (LEEP)
Status: UNKNOWN
Conditions: Cervical Intraepithelial Neoplasia|Cervical Cancer
Interventions: DRUG: Tachosil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Combination Chemotherapy Followed by Radiation Therapy Before Surgery in Treating Patients With Stage IIIB NSCLC
Status: COMPLETED
Conditions: Lung Cancer
Interventions: RADIATION: Hyperfractionated|DRUG: Taxotere/Cisplatin|PROCEDURE: conventional surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Lanreotide Autogel (ATG) in Combination With Temozolomide in Subjects With Thoracic Neuroendocrine Tumors.
Status: COMPLETED
Conditions: Neuroendocrine Tumours
Interventions: DRUG: Lanreotide (Autogel formulation) and Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A SAD/MAD Study to Evaluate the Safety, Tolerability, PK and PD of MT2004
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: MT2004|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of User Experience With Wheelsoft Wheels Intalled on a Wheelchair Compared With Normal Wheels.
Status: COMPLETED
Conditions: Back Pain|Personal Satisfaction|Fatigue
Interventions: DEVICE: Shock absorbing wheelchair
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Etomidate vs Propofol-Induction Characteristics
Status: COMPLETED
Conditions: Hemodynamics|Side Effects
Interventions: DRUG: Inj Etomidate|DRUG: Injection Propofol|DRUG: Placebo for Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: High-intensity Exercise After Treatment
Status: TERMINATED
Conditions: Breast Cancer|Breast Neoplasm Female
Interventions: BEHAVIORAL: High-Intensity Interval Training|BEHAVIORAL: Moderate-Intensity Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Evaluate Efficacy and Safety of HCP1803 in Patients With Essential Hypertension
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: HCP1803-3|DRUG: RLD2002|DRUG: HPP2003-3|DRUG: HPP2004
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Symptom-specific TMS Targets for Depression and Anxiety
Status: COMPLETED
Conditions: Depression|Anxiety|Major Depressive Disorder
Interventions: PROCEDURE: Transcranial magnetic stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Repeated Transcranial Magnetic Stimulation on Aggressive Impulsive Behavior in Patients With Borderline Personality Disorder in a Social Exclusion Paradigm.
Status: UNKNOWN
Conditions: Borderline Personality Disorder
Interventions: DEVICE: repeated transcranial magnetic stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Postoperative Outcomes of PCNL vs RIRS in Obese Patients With Pelvic 1.5:3 cm Renal Stones
Status: COMPLETED
Conditions: Renal Stones
Interventions: PROCEDURE: percutaneous nephrolithotomy|PROCEDURE: retrograde intrarenal surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Two or Six cm From Pylorus at Laparoscopic Sleeve Gastrectomy
Status: COMPLETED
Conditions: Morbid Obesity
Interventions: PROCEDURE: distance of dissection of gastrocolic ligament from pylorus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: The Effect of Natural Protein vs. Protein Supplements on Peritoneal Dialysis Patients
Status: COMPLETED
Conditions: Peritoneal Dialysis Complication|Hypoalbuminemia|Malnutrition
Interventions: BEHAVIORAL: increased protein intake via natural foods|BEHAVIORAL: increase protein intake via protein supplements
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety of Sabin Inactivated Poliovirus Vaccine in Adults, Children and Infants and Lot Consistency Immunogenicity, and Safety of the msIPV in 2 Months Old Infants
Status: COMPLETED
Conditions: Poliomyelitis
Interventions: BIOLOGICAL: Experimental vaccine|BIOLOGICAL: IPV control vaccine|BIOLOGICAL: single-person sIPV control vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Digestion of Gluten in the Presence of Enzymes
Status: COMPLETED
Conditions: Main Focus: Gluten and Starch Digestibility
Interventions: DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: Elevase®|DIETARY_SUPPLEMENT: DE111®|OTHER: Meal A|OTHER: Meal B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Risk Factor of Anterior Cruciate Ligament Rupture After Ligamentoplasty : What is the Importance of a Relative Deficit of Contralateral Hamstrings Assessed by Isokinetic in Postoperative ?
Status: COMPLETED
Conditions: Anterior Cruciate Ligament Rupture
Interventions: PROCEDURE: Isokinetic evaluation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Prospective Comparative Study to Compare Safety and Effectiveness of Two Vertebral Compression Fracture Reduction Techniques
Status: COMPLETED
Conditions: Spinal Fractures|Vertebral Compression Fractures|Back Injuries|Osteoporosis
Interventions: DEVICE: Vertebral fracture surgery SpineJack®|PROCEDURE: Balloon Kyphoplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Mild Class II Malocclusion in Adult Patients With Clear Aligners Versus Fixed Multibracket Therapy
Status: RECRUITING
Conditions: Malocclusion|Class II Malocclusion
Interventions: DEVICE: clear aligners|DEVICE: traditional treatment Fixed appliances with class II elastics.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparative Study for Non-Hodgkin's Lymphoma in Hepatitis B Virus Carriers
Status: COMPLETED
Conditions: Non-Hodgkin's Lymphoma
Interventions: DRUG: Cyclophosphamide Epirubicin Etoposide Prednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sustaining Physical Activity After Cancer Exercise Sessions
Status: RECRUITING
Conditions: Exercise Oncology|Physical Activity Behavior|Behavior Change Interventions
Interventions: BEHAVIORAL: Responder Monthly Behavior Change Discussion Sessions|BEHAVIORAL: Incomplete Responder Monthly Behavior Change Discussion Sessions|BEHAVIORAL: Incomplete Responder Monthly Behavior Change Discussion Sessions + Bi-Weekly Exercise Sessions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Ultrasound Guided Rhomboid Intercostal Block for Myofascial Pain Syndrome
Status: COMPLETED
Conditions: Myofascial Pain Syndrome
Interventions: OTHER: ultrasound guided rhomboid intercostal block
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Primary Care Intervention to Reduce Prescription Opioid Overdoses
Status: COMPLETED
Conditions: Pain|Drug Overdose|Opioid Use Disorders
Interventions: BEHAVIORAL: Motivational intervention|BEHAVIORAL: Psycho-educational control|OTHER: Long-term opioid therapy informed consent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Prepare to Quit - A Clinical Trial to Help People Quit Smoking in a Community Dental Clinic Setting
Status: UNKNOWN
Conditions: Smoking|Smoking Cessation
Interventions: BEHAVIORAL: Tooth Whitening|BEHAVIORAL: Motivational Counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: An Extension Trial to a Phase I Dose Escalation Study of Gimatecan Administered Orally 5 Consecutive Days to Japanese Patients With Advanced Solid Tumor
Status: COMPLETED
Conditions: Advanced Solid Tumors
Interventions: DRUG: Gimatecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Post-operative Pain at Umbilical Wound After Laparoscopic Cholecystectomy With Transumbilical Versus Infraumbilical Incision
Status: COMPLETED
Conditions: Pain, Postoperative|Gallstone
Interventions: PROCEDURE: transumbilical incision|PROCEDURE: Infra umbilical incision
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Properties of Isosorbide-5-mononitrate Under Fasting and Fed Condition in Healthy Male Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Elantan SR 60 mg|DRUG: Imdur SR 60 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Nivolumab, Docetaxel, Cisplatin Therapy Followed by Surgery and Radiation Therapy for Resectable High Grade Salivary Gland Carcinoma
Status: RECRUITING
Conditions: High-grade Salivary Gland Carcinoma
Interventions: DRUG: nivolumab, docetaxel, cisplatin Group
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Whole-Body Periodic Acceleration Therapy To Aches and Pains
Status: UNKNOWN
Conditions: Pain|Stiffness|Abnormal Gait|Balance
Interventions: DEVICE: Whole body periodic acceleration (Exer-Rest)
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Surgical Pulmonary Embolectomy Versus Catheter-directed Thrombolysis in the Treatment of Pulmonary Embolism: A Non-inferiority Study
Status: COMPLETED
Conditions: Acute Pulmonary Embolism (PE)
Interventions: PROCEDURE: surgical pulmonary embolectomy|COMBINATION_PRODUCT: catheter-directed thrombolysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Study of Efficacy of 10 mg Dequalinium Chloride (Fluomizin) in the Local Treatment of Bacterial Vaginosis
Status: COMPLETED
Conditions: Bacterial Vaginosis
Interventions: DRUG: Dequalinium chloride|DRUG: Clindamycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: LIVInG With chrONic Cancer TrEatments (LONGEVITI) Study
Status: RECRUITING
Conditions: Cancer|Tyrosine Kinase Mutation|Breast Cancer|Melanoma|Multiple Myeloma|Chronic Leukemia|Prostate Cancer|Ovarian Cancer|Colorectal Cancer|Lung Cancer
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effectiveness of Adding Cupping Therapy in Patients With Nonspecific Chronic Lumbar Pain
Status: COMPLETED
Conditions: Low Back Pain, Mechanical|Low Back Pain, Postural|Lower Back Pain Chronic|Low Back Pain, Posterior Compartment
Interventions: OTHER: muscle strengthening exercises|OTHER: muscle strengthening exercises and dry cupping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of OC000459 on Eosinophilic Airway Inflammation in Severe Asthma
Status: COMPLETED
Conditions: Severe Eosinophilic Asthma
Interventions: DRUG: OC000459|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Algarve Active Ageing - Cardiac and Osteoarthritis Rehabilitation (A3-COR)
Status: RECRUITING
Conditions: Osteoarthritis, Knee|Myocardial Infarction, Acute|Hypertension|Dyslipidemias|Type 2 Diabetes|Smoking Habit
Interventions: OTHER: Physical Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Long-Term Safety and Efficacy of Bimekizumab in Subjects With Psoriatic Arthritis
Status: COMPLETED
Conditions: Psoriatic Arthritis
Interventions: DRUG: Bimekizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of a Brown Seaweed Extract Rich in Polyphenols on Glycemic Response to Sucrose in Human
Status: COMPLETED
Conditions: Hyperglycemia
Interventions: DIETARY_SUPPLEMENT: Reduction of glycemic index of ingested foods
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Monosialoganglioside Preventing Neurotoxicity Induced by Albumin-bound Paclitaxel Chemotherapy in Lung Cancer Patients
Status: UNKNOWN
Conditions: Neurotoxicity
Interventions: DRUG: monosialoganglioside
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Clinical Trial Assessing Two Protocols to Withdraw Non-invasive Ventilation in Hypercapnic Respiratory Failure
Status: COMPLETED
Conditions: Hypercapnic Respiratory Failure
Interventions: DEVICE: Nocturnal non-invasive ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety, Immunological Effect and Efficacy of the Combined Application of MPL and Grass Pollen Allergen
Status: COMPLETED
Conditions: Type I Hypersensitivity
Interventions: BIOLOGICAL: OralvacB2MPL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Local Continuous Wound Infusion of Anesthetics in the Management of Post-operative Pain After Total Hip Arthroplasty.
Status: TERMINATED
Conditions: Pain
Interventions: DRUG: Levobupivacaine|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Pilot Study Assessing the Feasibility of Treating Foot Drop With the Neurostep™ System.
Status: COMPLETED
Conditions: Stroke|Craniocerebral Trauma
Interventions: DEVICE: Neurostep™ System
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Promoting Physical Activity in Chronic Obstructive Pulmonary Disease (COPD) Through New Technology and Health Coaching
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease|Physical Activity
Interventions: BEHAVIORAL: Activity monitor/smartphone health coaching
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Telmisartan Plus Exercise to Improve Functioning in Peripheral Artery Disease
Status: COMPLETED
Conditions: Peripheral Artery Disease
Interventions: BEHAVIORAL: Supervised Treadmill Exercise Therapy|DRUG: Telmisartan|OTHER: "No exercise" control group|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Topical Oestrogens and Antimuscarinics In The Treatment Of Detrusor Overactivity
Status: COMPLETED
Conditions: Overactive Bladder
Interventions: DRUG: Tolterodine 4 mg|DRUG: arm 2: Tolterodine 4 mg + local oestrogens once daily for 12 weeks
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose:
Clinical trial: Vitamin D in Healthy Adults After Strenuous Endurance Exercise
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Vitamin D|DIETARY_SUPPLEMENT: Medium-chain triglycerides
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Skin Adhesive to Subcuticular Suture Wound Closure After Port Placement
Status: COMPLETED
Conditions: Wound Closure After Port Catheter Implantation
Interventions: PROCEDURE: Suture|DEVICE: Experimental: Histoacryl®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Antitussive Effect of a Naturally Flavored Syrup Containing Diphenhydramine, Compared With Dextromethorphan and Placebo
Status: COMPLETED
Conditions: Cough Reflex Sensitivity
Interventions: DRUG: diphenhydramine/phenylephrine/cocoa; dextromethorophan; placebo|DRUG: diphenhydramine/phenylephrine/cocoa; placebo; dextromethorphan|DRUG: dextromethorphan; diphenhydramine/phenylephrine/cocoa; placebo|DRUG: dextromethorophan; placebo; diphenhydramine/phenylephrine/cocoa|DRUG: placebo; diphenhydramine/phenylephrine/cocoa; dextromethorphan|DRUG: placebo; dextromethorphan; diphenhydramine/phenylephrine/cocoa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Total Marrow and Lymphoid Irradiation and Chemotherapy for Myelodysplastic Syndrome or Acute Leukemia
Status: UNKNOWN
Conditions: Myelodysplastic Syndromes|Acute Leukemia
Interventions: RADIATION: total body irradiation|RADIATION: total marrow and lymphoid irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of US-ATG-F to Prevent Chronic Graft Versus Host Disease (GVHD)
Status: COMPLETED
Conditions: GVHD|Adult Acute Myeloid Leukemia|Adult Acute Lymphoid Leukemia|Myelodysplastic Syndrome
Interventions: BIOLOGICAL: US-ATG-F|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study to Assess Safety, Tolerability and Clinical Activity of BGB-290 in Combination With Temozolomide (TMZ) in Participants With Locally Advanced or Metastatic Solid Tumors
Status: COMPLETED
Conditions: Locally Advanced or Metastatic Solid Tumors
Interventions: DRUG: Pamiparib|DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized Controlled Trial Comparing Chondro-Gide® to Microfracture Alone for Treatment of Knee Cartilage Defects.
Status: COMPLETED
Conditions: Cartilage Injury|Osteochondritis Dissecans
Interventions: PROCEDURE: Microfracture|DEVICE: Chondro-Gide sutured|DEVICE: Chondro-Gide glued
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Acceptance of GourMed© Prepackaged Nutritional Products in the Elderly Dysphagic Patient: MODiet Project
Status: RECRUITING
Conditions: Dysphagia
Interventions: DIETARY_SUPPLEMENT: GourMed© meal
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Tele-epic (Telemedicine for Epilepsy Care)
Status: UNKNOWN
Conditions: Epilepsy|Epileptic Encephalopathy|Refractory Epilepsy
Interventions: PROCEDURE: Telemedicine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study of High-Dose Vit D Versus Standard of Care Vit D Supplementation
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast|Breast Cancer|Osteoporosis
Interventions: DIETARY_SUPPLEMENT: High Dose Vitamin D|DIETARY_SUPPLEMENT: Standard of Care Vitamin D
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: H5N8 Mix and Match With or Without AS03 or MF59 in Healthy Adults: Immunology
Status: COMPLETED
Conditions: Avian Influenza
Interventions: DRUG: AS03|DRUG: MF59|BIOLOGICAL: Monovalent Influenza A/H5N8 vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Study Providing Monotherapy (Sitaxsentan) And Combination Therapy (Sitaxsentan+Sildenafil) To Subjects With Pulmonary Arterial Hypertension (PAH) To Assess Long-Term Safety
Status: TERMINATED
Conditions: Pulmonary Arterial Hypertension|Pulmonary Hypertension
Interventions: DRUG: Sitaxsentan|DRUG: Sitaxsentan and Sildenafil
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transverse Abdominal Block for Analgesia in Casarean Section
Status: COMPLETED
Conditions: Analgesia Disorder
Interventions: DRUG: Bupivacine group|DRUG: Dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Therapeutic Effect of Botulinum Toxin A for the Treatment of Plantar Fasciitis.
Status: COMPLETED
Conditions: Plantar Fascitis|Botulinum Toxins, Type A
Interventions: DRUG: Betamethason Sodium Phosphate|DRUG: Ropivacaine|DRUG: Botulinum Toxins, Type A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 5HTP Regulation Of Asthma In Children
Status: RECRUITING
Conditions: Mild or Moderate Asthma With Allergic Sensitization
Interventions: DRUG: 5-Hydroxytryptophan|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Efficacy and Safety of N02RS1 in Patient With Acute Bronchitis
Status: COMPLETED
Conditions: Acute Bronchitis
Interventions: DRUG: N02RS1 1200mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Evaluation of Serplulimab Plus Chemo in SCLC Transformed From EGFR-mutated NSCLC After Treatment
Status: RECRUITING
Conditions: Small-cell Lung Cancer
Interventions: DRUG: Serplulimab|DRUG: SOC
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BIVV020 (SAR445088) n Prevention and Treatment of Antibody-mediated Rejection (AMR)
Status: RECRUITING
Conditions: Transplant Rejection
Interventions: DRUG: BIVV020 (SAR445088)|DRUG: Intravenous immunoglobulin (IVIg)|DRUG: Rituximab or biosimilar|DRUG: Antithymocyte globulin (ATG)|DRUG: Tacrolimus|DRUG: Mycophenolate|DRUG: Corticosteroids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PYLARIFY® PET/CT or PET/MRI in Men With Favorable Intermediate Risk (FIR) Prostate Cancer
Status: RECRUITING
Conditions: Prostate Cancer
Interventions: DRUG: Piflufolastat F 18 Intravenous Solution [PYLARIFY]
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Preventing Adverse Incisional Outcomes at Cesarean Multicenter Trial
Status: TERMINATED
Conditions: Surgical Wound Infection|Cesarean Section
Interventions: DEVICE: Prophylactic NPWT|DEVICE: Standard Dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Food, Rabeprazole, Methotrexate and Formulation on the Pharmacokinetics (PK) of GDC-0853 and the Effect of GDC-0853 on the PK of Methotrexate in Healthy Subjects
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: Folic Acid|DRUG: GDC-0853|DRUG: Methotrexate|DRUG: Rabeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Effect of Dulaglutide on How the Body Handles Oral Contraceptive in Healthy Female Participants
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Ortho-Cyclen|BIOLOGICAL: Dulaglutide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study of the Effects of Inhaled Fluticasone Furoate/GW642444 on the Hypothalamic-Pituitary-Adrenal (HPA) Axis
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Placebo Inhalation Powder|DRUG: Fluticasone Furoate/GW642444 Inhalation Powder|DRUG: Fluticasone Furoate/GW642444 Inhalation Powder|DRUG: Placebo Oral Capsule|DRUG: Prednisolone Oral Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of a Nutritional Consultation and Exercise Program in Esophageal Cancer Patient
Status: COMPLETED
Conditions: Esophageal Cancer
Interventions: BEHAVIORAL: nutritional consultation and exercise program|BEHAVIORAL: usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Proactive Clinical Ethics Consultations on End-of-life Care of the Critically Ill in the Intensive Care Settings
Status: UNKNOWN
Conditions: Proactive Clinical Ethics Consultation|the Critically Ill
Interventions: OTHER: proactive clinical ethics consultation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Safety, Tolerability, Pharmacokinetics and Activity of GS-9450 in Adults With Non-Alcoholic Steatohepatitis (NASH)
Status: COMPLETED
Conditions: Nonalcoholic Steatohepatitis
Interventions: DRUG: GS-9450|DRUG: GS-9450 Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic and Pharmacodynamic (PK and PD) Study of Fluticasone Propionate and Salmeterol Combination Product Delivered in a Capsule-based Inhaler and in a Multi-dose Dry Powder Inhaler in Moderate Asthma Patients and Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD) Patients.
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: SERETIDE Rotacaps|DRUG: SERETIDE Diskus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ebastine in Combination With Docetaxel as a Treatment for Castration-resistant Metastatic Prostate Cancer
Status: RECRUITING
Conditions: Metastatic Castration-resistant Prostate Cancer
Interventions: DRUG: Docetaxel + Ebastine|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigation of the Benefit of Using an Autologous Platelet-rich Fibrin Matrix (Obsidian ASG®) for Treatment of Anastomosis During Rectal Surgery
Status: ACTIVE_NOT_RECRUITING
Conditions: Anastomotic Leak Rectum
Interventions: DEVICE: Obsidian ASG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Oral Microencapsulated Diindolylmethane in Treating Patients With Stage II-III Triple Negative, Androgen Receptor Positive Breast Cancer Who Have Undergone Chemotherapy and Surgery
Status: WITHDRAWN
Conditions: Breast Cancer Female
Interventions: DRUG: oral microencapsulated diindolylmethane|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: NIMBUS: Nivolumab Plus Ipilimumab in Metastatic Hypermutated HER2-negative Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Nivolumab|DRUG: Ipilimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase II Trial to Evaluate the Efficacy of AZD6094 (HMPL-504) in Patients With Papillary Renal Cell Carcinoma (PRCC)
Status: COMPLETED
Conditions: Papillary Renal Cell Cancer
Interventions: DRUG: AZD6094
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Measuring Thickness of the Normal Diaphragm in Children Via Ultrasound.
Status: COMPLETED
Conditions: Mechanical Ventilation Complication|Pediatric ALL|Intensive Care Unit Acquired Weakness
Interventions: DIAGNOSTIC_TEST: diaphragm thickness and thickening fraction
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Evaluation of Different Phone Solutions in CI and Hearing Aid Users and Bimodal Recipients
Status: COMPLETED
Conditions: Hearing Loss, Binaural|Hearing Loss, Monaural
Interventions: DEVICE: standard telephone setting|DEVICE: DECT|DEVICE: EasyCall|DEVICE: DuoPhone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: AVJ-514 Japan Trial
Status: COMPLETED
Conditions: Mitral Stenosis With Insufficiency|Functional Mitral Regurgitation|Mitral Insufficiency|Mitral Valve Incompetence|Mitral Valve Regurgitation
Interventions: DEVICE: AVJ-514
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MOSAIC - Multicenter International Study of Oxaliplatin/ 5FU-LV in the Adjuvant Treatment of Colon Cancer
Status: COMPLETED
Conditions: Colonic Neoplasms
Interventions: DRUG: Oxaliplatin (SR96669)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of a Combined Oral Contraceptive of Estradiol Valerate and Dienogest in Healthy Female Subjects
Status: COMPLETED
Conditions: Contraception
Interventions: DRUG: EV/DNG (Qlaira, BAY86-5027)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effect of Enamel Matrix Derivatives on Root Coverage Esthetic Score
Status: COMPLETED
Conditions: Gingival Recession|Periodontal Diseases
Interventions: PROCEDURE: enamel matrix derivatives
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT