pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: MUSE Study to Evaluate the Pharmacokinetics, Safety and Tolerability of S6G5T-3
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: S6G5T-3|DRUG: Retin-A® 0.1% Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of Iyengar Yoga on the Bio-functional Age of Postmenopausal Women
Status: RECRUITING
Conditions: Postmenopausal|Postmenopausal Flushing
Interventions: BEHAVIORAL: Iyengar Yoga
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Long Term Effects of Tyrosine Kinase Inhibitor Therapy on Ovarian Reserve and Fertility in Patients With Chronic Myeloid Leukemia or Gastrointestinal Stromal Tumor
Status: WITHDRAWN
Conditions: Chronic Myelogenous Leukemia, BCR-ABL1 Positive|Gastrointestinal Stromal Tumor|Premenopausal
Interventions: OTHER: Cytology Specimen Collection Procedure|OTHER: Laboratory Biomarker Analysis|OTHER: Questionnaire Administration|PROCEDURE: Ultrasonography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Intramuscular Ropivacaine Injections for Treatment of Pediatric Headache
Status: COMPLETED
Conditions: Headache|Migraine
Interventions: DRUG: Ropivacaine|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Physical Activity Regimens as Treatments for Obstructive Sleep Apnea
Status: COMPLETED
Conditions: Obstructive Sleep Apnea
Interventions: BEHAVIORAL: moderate-intensity aerobic and resistance training|BEHAVIORAL: low-intensity stretching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Growth, Safety and Tolerance of a Rice Protein Hydrolysate Formula in Infants With Cow's Milk Protein Allergy
Status: TERMINATED
Conditions: Cow's Milk Allergy
Interventions: OTHER: HRF|OTHER: eHF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: HAIC Versus TACE for Large and Unresectable Hepatocellular Carcinoma Staged BCLC A/B
Status: COMPLETED
Conditions: Hepatocellular Carcinoma
Interventions: PROCEDURE: Hepatic arterial infusion|PROCEDURE: Transarterial chemoembolization|DRUG: Folfox Protocol|DRUG: TACE Drug Protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Chemo-mechanical Caries Removal Materials in Caries Removal
Status: COMPLETED
Conditions: Dental Caries
Interventions: PROCEDURE: Traditional Escavation|PROCEDURE: Excavation with Sodium Hypochlorite Gel 2.5%.|PROCEDURE: Excavation with Papacarie Duo|PROCEDURE: Excavation with Brix3000|PROCEDURE: Excavation with Selecti-solve
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of DL-NBP in Patients With Mild Subcortical Ischemic Vascular Dementia
Status: UNKNOWN
Conditions: Subcortical Vascular Dementia|Cerebral Small Vessel Diseases
Interventions: DRUG: NBP|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Efficacy of Saroglitazar Mg 4 mg in Liver Transplant Recipients With NAFLD
Status: COMPLETED
Conditions: Liver Transplant; Complications|NAFLD
Interventions: DRUG: Saroglitazar
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Obstructive Sleep Apnea Syndrome (OSA) and Getemed
Status: COMPLETED
Conditions: Sleep Apnea, Obstructive
Interventions: DEVICE: home polysomnography (GETEMED)|DEVICE: standard polysomnography (BRAINNET II)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of DNL593 in Healthy Participants and Participants With Frontotemporal Dementia (FTD-GRN)
Status: ACTIVE_NOT_RECRUITING
Conditions: Frontotemporal Dementia
Interventions: DRUG: DNL593|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Meropenem Standard 30 Minute Infusion Versus Prolonged 3 Hour Infusion in Intensive Care Unit (ICU) Patients
Status: COMPLETED
Conditions: Sepsis
Interventions: DRUG: Meropenem short infusion|DRUG: Meropenem extended infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MAGnesium Adjunction in Alcohol Withdrawal Syndrome: a Multicenter Assessment (MAGMA)
Status: COMPLETED
Conditions: Alcohol Withdrawal Syndrome
Interventions: DRUG: Magnesium|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dasatinib and Osimertinib (AZD9291) in Advanced Non-Small Cell Lung Cancer With EGFR Mutations
Status: TERMINATED
Conditions: EGFR Gene Mutation|Nonsmall Cell Lung Cancer
Interventions: DRUG: Dasatinib|DRUG: Osimertinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Heart and Kidney Ketones Metabolism
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Fasting with exogenous ketone salt supplement|DIETARY_SUPPLEMENT: Post-Prandial with exogenous ketone salt supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Green Banana BIOmass Consumption in Patients With Pre-diabetes and Diabetes MELlitus (The BIOMEL Study)
Status: UNKNOWN
Conditions: Diabetes Mellitus|Pre-diabetes
Interventions: DIETARY_SUPPLEMENT: Green banana biomass
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tissue and Blood Biomarkers From Patients With Stage III or Stage IV Melanoma Treated With Ipilimumab With or Without Sargramostim
Status: COMPLETED
Conditions: Melanoma (Skin)
Interventions: GENETIC: RNA analysis|GENETIC: in situ hybridization|GENETIC: polymerase chain reaction|OTHER: enzyme-linked immunosorbent assay|OTHER: flow cytometry|OTHER: immunohistochemistry staining method|OTHER: laboratory biomarker analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phase 1a/1b BGB-290 for Advanced Solid Tumors.
Status: COMPLETED
Conditions: For Participants With Advanced Solid Tumors Failed With Previous Lines of Treatment
Interventions: DRUG: BGB-290|DRUG: BGB-290|DRUG: BGB-290|DRUG: BGB-290|DRUG: BGB-290
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety of GSK Biologicals' Live Attenuated Varicella Vaccine (VARILRIXTM).
Status: COMPLETED
Conditions: Varicella
Interventions: BIOLOGICAL: VarilrixTM
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Randomized Phase-II Study of Nivolumab Plus Ipilimumab vs. Standard of Care in Untreated and Advanced Non-clear Cell RCC
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Renal Cell Carcinoma
Interventions: DRUG: Ipilimumab plus nivolumab|DRUG: Standard Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Set-Point Study for Type 2 Diabetes: Evaluating the Use of an Insulin Only Bionic Pancreas System in Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DEVICE: Bionic Pancreas|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of an Allergen Vaccine in Patients With Allergic Rhino-Conjunctivitis and Asthma Due to House Dust Mite Allergy
Status: COMPLETED
Conditions: Perennial Allergic Rhinoconjunctivitis|Allergic Asthma
Interventions: BIOLOGICAL: CYT005-AllQbG10
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial to Evaluate the Efficacy and Safety of TNM001 for the Prevention of Lower Respiratory Tract Infection Caused by Respiratory Syncytial Virus in Infants
Status: NOT_YET_RECRUITING
Conditions: Respiratory Syncytial Virus Infections
Interventions: BIOLOGICAL: TNM001|BIOLOGICAL: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: S9810: Gemcitabine Plus Cisplatin in Treating Patients With Malignant Mesothelioma of the Pleura That Cannot Be Removed by Surgery
Status: COMPLETED
Conditions: Malignant Mesothelioma
Interventions: DRUG: gemcitabine hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evidence-Based Approach to Empower Asian American Women in Cervical Cancer Screening
Status: RECRUITING
Conditions: Uterine Cervical Neoplasms
Interventions: BEHAVIORAL: Community-Based Education|BEHAVIORAL: Navigation to Screening|BEHAVIORAL: HPV Self-Sampling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Post-ICU Palliative Care Intervention (PIPCI) Trial
Status: COMPLETED
Conditions: Critical Illness|Frailty|Palliative Care
Interventions: BEHAVIORAL: Palliative Care Consultation|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of PEMF for Patients With Quadriceps Muscle Weakness After ACLR
Status: ACTIVE_NOT_RECRUITING
Conditions: Anterior Cruciate Ligament Injuries|Quadriceps Muscle Atrophy
Interventions: DEVICE: Pulse Electromagnetic Field|DEVICE: Sham Pulse Electromagnetic Field
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: ResQ Trial: Impact of an ITD and Active Compression Decompression CPR on Survival From Out-of-Hospital Cardiac Arrest
Status: TERMINATED
Conditions: Heart Arrest|Death, Sudden, Cardiac|Cardiopulmonary Resuscitation|Cardiac Arrest
Interventions: DEVICE: Use of an impedance threshold device (ITD) during the performance of active compression decompression CPR (ACD-CPR)|PROCEDURE: Standard cardiopulmonary resuscitation (S-CPR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: "A Randomized, Controlled, Evaluator-blinded Pilot Study to Evaluate the Effect of Automated Text Message Reminders on Patient Compliance With Topical Medications and Its Efficacy on Skin Disease Control in Adolescents and Adults With Mild to Moderate Acne"
Status: COMPLETED
Conditions: Acne|Patient Compliance
Interventions: OTHER: Text message reminders
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Phase I/II, Evaluate the Safety and Efficacy of BLEX 404 With Docetaxel in Patients With Advanced/Metastatic Triple Negative Breast Cancer.
Status: NOT_YET_RECRUITING
Conditions: Triple Negative Breast Cancer
Interventions: DRUG: BLEX 404 Oral Liquid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Phosphodiesterase Inhibitor Tadalafil as an Adjunct to Antidepressants in Major Depressive Disorder Patients
Status: RECRUITING
Conditions: Major Depressive Disorder
Interventions: DRUG: Tadalafil 5Mg Tab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Predictive and Prognostic Values of the Fibrinogen to Albumin Ratio and C-reactive Protien to Albumin Ratio in Systemic Lupus Erythematosus Patients
Status: NOT_YET_RECRUITING
Conditions: Systemic Lupus Erythematosus
Interventions: DIAGNOSTIC_TEST: Fibrinogen to albumin Ratio and C-reactive to Albumin Ratio
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Immunogenicity and Safety of GSK Biologicals' Infanrix/Hib in Children
Status: COMPLETED
Conditions: Acellular Pertussis|Diphtheria|Tetanus
Interventions: BIOLOGICAL: Infanrix™|BIOLOGICAL: Hiberix™
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Investigation of GSK2879552 in Subjects With Relapsed/Refractory Small Cell Lung Carcinoma
Status: TERMINATED
Conditions: Carcinoma, Small Cell
Interventions: DRUG: GSK2879552
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study Into the Cosmetic Results of Leukosan Adhesive
Status: COMPLETED
Conditions: Wound Healing Cosmetic Result
Interventions: DEVICE: Leukosan Adhesive|DEVICE: Transcutaneous suture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: WONDER-02 Trial: Plastic Stent vs. Lumen-apposing Metal Stent for Pancreatic Pseudocysts
Status: NOT_YET_RECRUITING
Conditions: Pancreatic Fluid Collection|Pancreatitis|Pancreatic Pseudocyst
Interventions: PROCEDURE: Plastic stent|PROCEDURE: LAMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Supplemental Effects of ELDOA in Addition to Thoracic Manipulation on Upper Back Pain, Thoracic Kyphosis and Forward Head Posture in Thoracic Hypomobility
Status: ENROLLING_BY_INVITATION
Conditions: Forward Head Posture|Thoracic Hypomobility|Upper Back Pain
Interventions: PROCEDURE: Thoracic Manipulation|PROCEDURE: Chin tuck in exercises|PROCEDURE: Thoracic Extension Exercise|PROCEDURE: Scapular Retraction Exercises|DEVICE: Hot Pack|DEVICE: TENS|PROCEDURE: ELDOA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Steroids Versus Gabapentin
Status: COMPLETED
Conditions: Sciatica|Radiculopathy
Interventions: PROCEDURE: epidural steroid injection|PROCEDURE: Sham epidural steroid injection|DRUG: Gabapentin|DRUG: Placebo gabapentin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Performance of Robotic Microsurgery Systems
Status: COMPLETED
Conditions: Robotic Surgery|Microsurgery|Anastomosis
Interventions: DEVICE: Robotic anastomosis (Symani surgical system and RoboticScope)|PROCEDURE: Conventional anastomosis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Neratinib and Cetuximab to Treat Patients With Quadruple Wild-Type Metastatic Colorectal Cancer
Status: WITHDRAWN
Conditions: Colorectal Cancer
Interventions: DRUG: Cetuximab|DRUG: Neratinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PS-Omega3 Supplementation to Attention Deficit Hyperactivity Disorder (ADHD) Children
Status: UNKNOWN
Conditions: ADHD
Interventions: DIETARY_SUPPLEMENT: PS-Omega3 conjugate supplementation|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Quadratus Lumborum Block (Transmuscular Approach) VS. TransversusAbdominus Plane Block(Unilateral Posterior Approach) for Perioperative Analgesia in Patients Undergoing Flank Incision Surgeries.
Status: COMPLETED
Conditions: Anesthesia, Local
Interventions: PROCEDURE: transmuscular QL block|PROCEDURE: Transversus Abdominus Plane block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Coadministration of Ezetimibe and Simvastatin in Patients With Primary Hypercholesterolemia (P05457)
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DRUG: Ezetimibe|DRUG: Simvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Placebo Controlled, Dose Response, Safety and Immunogenicity Study of Vesicular Stomatitis Virus (VSV) Ebola Vaccine in Healthy Adults (V920-004)
Status: COMPLETED
Conditions: Ebola Virus
Interventions: BIOLOGICAL: V920 Vaccine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Acetazolamide's Headache Inducing Characteristics and Effects on the Cerebral Arteries and Blood Flow
Status: COMPLETED
Conditions: Headache|Migraine
Interventions: DRUG: Acetazolamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Adolescent Type 1 Diabetes Treatment With SGLT2i for hyperglycEMia & hyPerfilTration Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Diabetes Mellitus, Type 1
Interventions: DRUG: Dapagliflozin 5mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessing Effect of Spinal Cord Stimulation on Pain and Quality of Life With Chemotherapy-Induced Peripheral Neuropathy
Status: RECRUITING
Conditions: Chemotherapy-Induced Peripheral Neuropathy|Hematopoietic and Lymphoid System Neoplasm|Malignant Solid Neoplasm
Interventions: OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration|PROCEDURE: Spinal Cord Stimulation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical, Cognitive and Neural Effects of Potentiation of ECT by rTMS in Treatment-Resistant Depression
Status: NOT_YET_RECRUITING
Conditions: Major Depressive Disorder
Interventions: DEVICE: Active rTMS|DEVICE: Sham rTMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Micophenolate Mofetil Versus Azathioprine in Myocarditis
Status: UNKNOWN
Conditions: Lymphocytic Myocarditis (Disorder)|Heart Failure|Dilated Cardiomyopathy|Cardiomyopathies|Sudden Cardiac Death
Interventions: DRUG: mycophenolate mofetil 2 g per day|DRUG: azathioprine of 150 [75; 150] mg per day
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Cluster-randomized Control Trial of PAX Good Behavior Game in Swedish Elementary Schools
Status: RECRUITING
Conditions: Well-being in Elementary School Children|Mental Health in Elementary School Children|Work-related Stress in Teachers|Academic Performance in Elementary School Children
Interventions: BEHAVIORAL: PAX Good Behavior Game|BEHAVIORAL: Count on Me!|BEHAVIORAL: Collegial Learning Community
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Interest of the Peak of Reticulocytes in Chronic Hemodialysis Patients Treated by Mircera Hemodialysis Population
Status: TERMINATED
Conditions: Renal Insufficiency, Chronic
Interventions: BIOLOGICAL: Reticera
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Safety and Pharmacokinetics of IMT504, an Immunomodulator and Tissue Repair Inducer
Status: RECRUITING
Conditions: Immune System
Interventions: DRUG: Oligonucleotides, Phosphorothioate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Pembrolizumab With REOLYSIN® and Chemotherapy in Patients With Advanced Pancreatic Adenocarcinoma
Status: COMPLETED
Conditions: Pancreatic Adenocarcinoma
Interventions: BIOLOGICAL: REOLYSIN®|DRUG: Chemotherapy|DRUG: Gemcitabine|DRUG: Irinotecan|DRUG: Leucovorin|DRUG: 5-fluorouracil|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Cell Changes in Blood and Tissue in Cancers of the Lung, Esophagus and Lung Lining
Status: RECRUITING
Conditions: Malignant Pleural Mesotheliomas NOS|Esophageal Cancers NOS|Lung Cancer NOS|Thoracic Cancers|Cancers of Non Thoracic Origin With Metastases to the Lungs or Pleura
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Laparoscopic Therapy of Endometrioma: Sclerotherapy vs Cystectomy in Patients With Unfinished Reproductive Plans
Status: RECRUITING
Conditions: Endometrioma|Endometriosis
Interventions: PROCEDURE: laparoscopic ethanol sclerotherapy|PROCEDURE: laparoscopic cystectomy of endometrioma
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preliminary Study of Safety and Efficacy of Policosanol
Status: COMPLETED
Conditions: Dyslipidemia|HIV Infections
Interventions: DRUG: Policosanol|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Adding Core Stabilization Training to Manuel Therapy in Temporomandibular Disorders
Status: COMPLETED
Conditions: Temporomandibular Disorders|Temporomandibular Joint Disorders
Interventions: OTHER: Core Stabilization Training|OTHER: Orofacial Manual Therapy|OTHER: Conventional Physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Rigid and Non-Rigid Interbody Fusion Device for Cervical Degenerative Disc Disease in Adults
Status: RECRUITING
Conditions: Cervical Disc Degeneration
Interventions: COMBINATION_PRODUCT: Z-Brace interbody fusion device|COMBINATION_PRODUCT: PEEK interbody fusion device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Pralatrexate With Vitamin B12 and Folic Acid in Patients With Relapsed or Refractory Peripheral T-cell Lymphoma
Status: COMPLETED
Conditions: Peripheral T-cell Lymphoma
Interventions: DRUG: Pralatrexate Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Platelet Rich Plasma for the Treatment of Genitourinary Syndrome of Menopause in Patients With Stage 0-III Breast Cancer
Status: COMPLETED
Conditions: Anatomic Stage 0 Breast Cancer AJCC v8|Anatomic Stage I Breast Cancer AJCC v8|Anatomic Stage IA Breast Cancer AJCC v8|Anatomic Stage IB Breast Cancer AJCC v8|Anatomic Stage II Breast Cancer AJCC v8|Anatomic Stage IIA Breast Cancer AJCC v8|Anatomic Stage IIB Breast Cancer AJCC v8|Anatomic Stage III Breast Cancer AJCC v8|Anatomic Stage IIIA Breast Cancer AJCC v8|Anatomic Stage IIIB Breast Cancer AJCC v8|Anatomic Stage IIIC Breast Cancer AJCC v8|Breast Adenocarcinoma|Genitourinary Syndrome of Menopause|Prognostic Stage 0 Breast Cancer AJCC v8|Prognostic Stage I Breast Cancer AJCC v8|Prognostic Stage IA Breast Cancer AJCC v8|Prognostic Stage IB Breast Cancer AJCC v8|Prognostic Stage II Breast Cancer AJCC v8|Prognostic Stage IIA Breast Cancer AJCC v8|Prognostic Stage IIB Breast Cancer AJCC v8|Prognostic Stage III Breast Cancer AJCC v8|Prognostic Stage IIIA Breast Cancer AJCC v8|Prognostic Stage IIIB Breast Cancer AJCC v8|Prognostic Stage IIIC Breast Cancer AJCC v8
Interventions: OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration|BIOLOGICAL: Therapeutic Autologous Platelet-rich Plasma
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluating the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of BIIB054 in Participants With Parkinson's Disease
Status: TERMINATED
Conditions: Parkinson's Disease
Interventions: DRUG: Placebo|DRUG: BIIB054
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Contingency Management for Methamphetamine Abstinence and HIV Post-Exposure Prophylaxis in Men Who Have Sex With Men
Status: COMPLETED
Conditions: Amphetamine-Related Disorders|HIV|HIV Infections
Interventions: DRUG: Truvada|BEHAVIORAL: CM
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Single-patient Clinical Trial of MAS825 in a Patient With XIAP Deficiency
Status: COMPLETED
Conditions: X-linked Lymphoproliferative Syndrome Type 2 (XLP-2)
Interventions: DRUG: MAS825
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aqueous Vascular Endothelial Growth Factor (VEGF) Levels in Type 3 Neovascularization
Status: COMPLETED
Conditions: Age-related Macular Degeneration
Interventions: PROCEDURE: Aqueous sample|PROCEDURE: Aqueous sample|PROCEDURE: Aqueous sample|PROCEDURE: Aqueous sample
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Conservative Therapy Versus Epidural Steroids for Cervical Radiculopathy
Status: COMPLETED
Conditions: Cervical Radiculopathy
Interventions: OTHER: Gabapentin and/or Nortriptyline, Physical therapy|PROCEDURE: Epidural Steroid Injections (ESI)|OTHER: Combination treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Dose Escalation Trial Evaluating Safety, Efficacy, and Pharmacokinetics of TransCon CNP Administered Once Weekly in Prepubertal Children With Achondroplasia
Status: ACTIVE_NOT_RECRUITING
Conditions: Achondroplasia
Interventions: DRUG: TransCon CNP|DRUG: Placebo for TransCon CNP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effectiveness, Safety, and Tolerability of Duac Akne Gel and Epiduo Gel in the Treatment of Facial Acne Vulgaris
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: Epiduo Gel|DRUG: Duac Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Anti-Tumor Study of Oral EPI-506 for Patients With Metastatic Castration-Resistant Prostate Cancer
Status: TERMINATED
Conditions: Prostatic Neoplasms|Genital Neoplasms, Male|Genital Diseases, Male|Prostatic Diseases
Interventions: DRUG: EPI-506
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intravitreal Diclofenac Versus Intravitreal Ranibizumab for the Treatment of Diabetic Macular Edema.
Status: UNKNOWN
Conditions: Diabetic Macular Edema
Interventions: DRUG: Diclofenac Sodium 0.1 ml containing 500µg|DRUG: Ranibizumab 0.5 mg Solution for Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ⁸⁹Zr-Df-IAB22M2C (CD8 PET Tracer) for PET/CT in Patients With Metastatic Solid Tumors
Status: COMPLETED
Conditions: Positron-Emission Tomography|Metastatic Solid Tumors
Interventions: DRUG: ⁸⁹Zr-Df-IAB22M2C
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Enabling Sleep Apnea Patient-Centered Care Via an Internet Intervention
Status: COMPLETED
Conditions: Sleep Apnea Syndromes
Interventions: BEHAVIORAL: i-PAP|BEHAVIORAL: Usual Care (Standard Care)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Efficacy and Safety of NT 201 (Botulinum Toxin) Compared With Placebo for the Treatment of Adult Participants With Essential Tremor in the Arm
Status: COMPLETED
Conditions: Essential Tremor of the Upper Limb
Interventions: DRUG: NT 201|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Feasibility Study to Assess Tenofovir and Maraviroc Protection Against HIV-1 in Cervical and Vaginal Explants
Status: COMPLETED
Conditions: Healthy Adult Females
Interventions: DRUG: Tenofovir|DRUG: Maraviroc
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Tibetan Yoga in Improving Fatigue and Sleep in Participants With Stage I-III Breast Cancer
Status: COMPLETED
Conditions: Anatomic Stage I Breast Cancer AJCC v8|Anatomic Stage IA Breast Cancer AJCC v8|Anatomic Stage IB Breast Cancer AJCC v8|Anatomic Stage II Breast Cancer AJCC v8|Anatomic Stage IIA Breast Cancer AJCC v8|Anatomic Stage IIB Breast Cancer AJCC v8|Anatomic Stage III Breast Cancer AJCC v8|Anatomic Stage IIIA Breast Cancer AJCC v8|Anatomic Stage IIIB Breast Cancer AJCC v8|Anatomic Stage IIIC Breast Cancer AJCC v8|Prognostic Stage I Breast Cancer AJCC v8|Prognostic Stage IA Breast Cancer AJCC v8|Prognostic Stage IB Breast Cancer AJCC v8|Prognostic Stage II Breast Cancer AJCC v8|Prognostic Stage IIA Breast Cancer AJCC v8|Prognostic Stage IIB Breast Cancer AJCC v8|Prognostic Stage III Breast Cancer AJCC v8|Prognostic Stage IIIA Breast Cancer AJCC v8|Prognostic Stage IIIB Breast Cancer AJCC v8|Prognostic Stage IIIC Breast Cancer AJCC v8|Breast Cancer
Interventions: DEVICE: Actigraph|OTHER: Best Practice|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration|OTHER: Sleep Diary|OTHER: Stretching|PROCEDURE: Yoga
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of the Natural Sweeteners Erythritol and Xylitol on Vascular Function in Obese Volunteers
Status: COMPLETED
Conditions: Obesity
Interventions: DIETARY_SUPPLEMENT: E967-Xylitol|DIETARY_SUPPLEMENT: E968-Erythritol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Speech Motor Learning and Retention (Aim 2)
Status: NOT_YET_RECRUITING
Conditions: Speech
Interventions: BEHAVIORAL: Adaptation|BEHAVIORAL: Adaptation baseline|DEVICE: Motor evoked potentials|DEVICE: Auditory evoked potentials|DEVICE: Somatosensory evoked potentials
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study Evaluating the Safety of Intranasal Administration of 400 μg of Fluticasone Propionate Twice a Day (BID) Using a Novel Bi-Directional Device in Subjects With Chronic Sinusitis With or Without Nasal Polyps
Status: COMPLETED
Conditions: Chronic Sinusitis With or Without Nasal Polyps
Interventions: DRUG: Fluticasone Propionate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Aquatic Exercise and Traditional Physical Therapy on Gout in Hypertensive Menopausal Women With Hyperuricemia
Status: UNKNOWN
Conditions: Gout
Interventions: OTHER: the Aquatic exercises +Traditional physical therapy programs +anti-hyperuricemia medication|OTHER: traditional physical therapy + anti-hyperuricemia medication
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Artificial Saliva Containing Cumin and Ginger Extract in Hemodialysis Patients With Xerostomia
Status: NOT_YET_RECRUITING
Conditions: Xerostomia
Interventions: DRUG: Artificial saliva containing cumin and ginger extract|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Simultaneous DBS of the GPi and the NBM in Patients With Parkinson's Disease and Mild Cognitive Impairment
Status: UNKNOWN
Conditions: Parkinson Disease|Mild Cognitive Impairment
Interventions: DEVICE: Deep brain stimulation implantation of a Vercise neurostimulation system in GPi and NBM.|DEVICE: GPi stimulation|DEVICE: NBM stimulation|DEVICE: Sham stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Impact of Drawtex in Venous Leg Ulcers
Status: COMPLETED
Conditions: Moderatley to Highly Exuding Venous Leg Ulcers
Interventions: DEVICE: Drawtex dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of an Anti-Tumor Necrosis Factor (TNF) Alpha Agent in Patients With Hand Osteoarthritis
Status: COMPLETED
Conditions: Hand Osteoarthritis
Interventions: OTHER: Adalimumab (Humira®)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intradermal Influenza Vaccine in the Young
Status: COMPLETED
Conditions: Influenza Viral Infections
Interventions: DRUG: Imiquimod ointment|DRUG: Aqueous cream|BIOLOGICAL: Intradermal influenza vaccine|BIOLOGICAL: Intramuscular influenza vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Epidemiology of Persistent Pulmonary Hypertension of the Newborn - SCOR in Lung Biology and Diseases in Infants and Children
Status: COMPLETED
Conditions: Lung Diseases|Cardiovascular Diseases|Defect, Congenital Heart|Heart Diseases|Persistent Fetal Circulation Syndrome
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Lifestyle Intervention in Chronic Ischemic Heart Disease and Diabetes
Status: COMPLETED
Conditions: Ischemic Heart Disease Chronic|Diabetes Mellitus, Type 2
Interventions: BEHAVIORAL: lifestyle intervention|BEHAVIORAL: usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Proactive Palliative Care Intervention in a Surgical ICU: Influence on Family Satisfaction and Patient Distress
Status: UNKNOWN
Conditions: Palliative Care
Interventions: OTHER: Proactive Palliative Care
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Respiratory Muscles Training in Patients With Dilated Cardiomyopathy
Status: COMPLETED
Conditions: Dilated Cardiomyopathy
Interventions: OTHER: Treadmill training|OTHER: Treadmill protocol and Respiratory training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of the Safety and Efficacy of Apremilast in Subjects With Moderate to Severe Alopecia Areata
Status: COMPLETED
Conditions: Alopecia Areata
Interventions: DRUG: Apremilast|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Role of GIP in Postprandial Splanchnic Blood Flow Distribution and Metabolism in Patients With Type 2 Diabetes
Status: RECRUITING
Conditions: Blood Flow
Interventions: OTHER: Saline / placebo|OTHER: GIPR antagonist / study tool
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Long Term Study of YM060 in Female Patients With Diarrhea-predominant Irritable Bowel Syndrome
Status: COMPLETED
Conditions: Diarrhea-predominant Irritable Bowel Syndrome
Interventions: DRUG: YM060
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Learn About a New Medicine Called ARV-471 (PF-07850327) in People Who Have Advanced Metastatic Breast Cancer.
Status: RECRUITING
Conditions: Advanced Breast Cancer
Interventions: DRUG: ARV-471|DRUG: Fulvestrant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Safety and Effectiveness of the Flex Robotic System for the Surgical Removal of Colorectal Lesions
Status: COMPLETED
Conditions: Colorectal Neoplasm
Interventions: PROCEDURE: Colonoscopy|PROCEDURE: Endoscopic Ultrasound|OTHER: Medical Chart Review|OTHER: Medical Device Usage and Evaluation|PROCEDURE: Resection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: A Retrospective Cohort Study on the Risk of Serious Infections in Rheumatoid Arthritis Patients Receiving Tocilizumab
Status: UNKNOWN
Conditions: Infection|Rheumatoid Arthritis
Interventions: DRUG: Tocilizumab|DRUG: Tumor Necrosis Factor Inhibitor (etanercept, infliximab, adalimumab, and golimumab)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Randomized Controlled Trial of Tranexamic Acid in Total Knee Arthroplasty: Intravenous vs. Topical
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DRUG: Topical Tranexamic Acid|DRUG: Intravenous Tranexamic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Pharmacokinetics of Benzoic Acid and Hippuric Acid After Topical Administration of GSK2585823 in Japanese Subjects With Acne Vulgaris
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: GSK2585823
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Calcineurin Free Immunosuppression in Renal Transplant Recipients
Status: COMPLETED
Conditions: Kidney Transplantation|Chronic Kidney Disease
Interventions: DRUG: Sirolimus|DRUG: Cyclosporine A|DRUG: Prednisone|DRUG: Mycophenolate mofetil|PROCEDURE: Protocol biopsies
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Stakeholder-enhanced Intervention to Improve the Decisional Partnership of Chronic Kidney Disease Dyads (IMPART)
Status: RECRUITING
Conditions: Decision Making, Shared|Family Caregiving|Chronic Kidney Disease
Interventions: BEHAVIORAL: ImPart - Improving Chronic Kidney Disease Decisional Partnerships
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of Suturing Technique Types on Pubocervical Fascia at Colpographhy Anterior for Cystocele Repair
Status: COMPLETED
Conditions: Pelvic Organ Prolapse
Interventions: PROCEDURE: Pubocervical fascia reconstruction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Xenon on Brain Injury After Aneurysmal Subarachnoid Hemorrhage
Status: NOT_YET_RECRUITING
Conditions: Subarachnoid Hemorrhage, Aneurysmal|Cerebral Injury|Cerebral Ischemia|Cerebral Infarction|Cardiac Event|Cardiac Failure
Interventions: DRUG: Xenon|DRUG: air/oxygen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Diathermy-Radiofrecuency Compared With Cavitation in Cellulitis Treatment
Status: COMPLETED
Conditions: Cellulitis
Interventions: OTHER: Experimental group|OTHER: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dopamine D-2 Antagonist Use in Poor Responders in IVF: a Randomized Controlled Trial
Status: WITHDRAWN
Conditions: in Vitro Fertilization|Poor Responder
Interventions: DRUG: metoclopramide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: PK of Serelaxin in Severe Renal Impairment and ESRD
Status: COMPLETED
Conditions: Renal Failure, Chronic|End-Stage Renal Disease
Interventions: DRUG: Serelaxin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Role of BMP Pathway in MDS Progression
Status: NOT_YET_RECRUITING
Conditions: Myelodysplastic Syndromes|Acute Myelogenous Leukemia
Interventions: BIOLOGICAL: Collection of EDTA (disodium salt of ethylenediaminetetraacetic acid) tubes of marrow during routine care
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy of a Supervised Intervention Protocol on Rounded Shoulder Posture and Shoulder ROM Among Saudi Young Females
Status: COMPLETED
Conditions: Postural; Defect
Interventions: OTHER: Active Stretching or Self-stretching exercises|OTHER: Active strengthening Or Self-Strengthening exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility Study of CVC Diagnosis Via Ultrasound in Children
Status: COMPLETED
Conditions: Ultrasound for Diagnosis of CVC Position in Children
Interventions: PROCEDURE: Ultrasound for diagnosis of CVC position in children
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Drug Interaction Study of SAR302503 in Patients With Solid Tumor
Status: COMPLETED
Conditions: Solid Tumor
Interventions: DRUG: SAR302503|DRUG: omeprazol|DRUG: metoprolol|DRUG: midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of Amodiaquine-Artesunate and Artemether-Lumefantrine for the Treatment of Uncomplicated Malaria
Status: COMPLETED
Conditions: Malaria, Falciparum
Interventions: DRUG: ASAQ Winthrop® Sanofi Aventis|DRUG: Coartem®, Novartis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Safety and Efficacy of Subcutaneously Injected Risankizumab in Adult Participants With Genital or Scalp Psoriasis
Status: RECRUITING
Conditions: Genital Psoriasis|Scalp Psoriasis
Interventions: DRUG: Risankizumab|DRUG: Placebo for Risankizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Randomised Placebo-controlled Venlafaxine-referenced Study of Efficacy and Safety of 5 and 10 mg of Vortioxetine (Lu AA21004) in Acute Treatment of Major Depressive Disorder in Adults
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: Placebo|DRUG: Vortioxetine (Lu AA21004)|DRUG: Venlafaxine XL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Thymoglobulin in Unrelated Hematopoietic Progenitor Cell Transplantation
Status: UNKNOWN
Conditions: Hematologic Malignancies
Interventions: BIOLOGICAL: Anti-Thymocyte Globulin (Rabbit)|OTHER: Patients will receive a standard preparative regimen (i.e. one that does not contain Thymoglobulin)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Liver Transplant Combined With Neoadjuvant Chemo-radiotherapy in the Treatment of Unresectable Hilar Cholangiocarcinoma. A Prospective Multicenter Study.
Status: RECRUITING
Conditions: Unresectable Cholangiocarcinoma
Interventions: DRUG: Neoadjuvant Chemo-radiotherapy|PROCEDURE: Liver Transplantation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Nicotinamide Riboside for Treating Elevated Systolic Blood Pressure and Arterial Stiffness in Middle-aged and Older Adults
Status: RECRUITING
Conditions: Hypertension|Aging
Interventions: DRUG: Nicotinamide riboside|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT