pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Pharmacokinetics and Drug Interaction Study Between DWC20141 and DWC20142 in Healthy Male Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: DWC20141|DRUG: DWC20142|DRUG: DWC20141, DWC20142
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Biomarkers in Stored Tumor Samples From Younger Patients With Liver Cancer
Status: WITHDRAWN
Conditions: Liver Cancer
Interventions: GENETIC: comparative genomic hybridization|GENETIC: molecular genetic technique|GENETIC: mutation analysis|GENETIC: polymerase chain reaction|GENETIC: proteomic profiling|OTHER: immunohistochemistry staining method|OTHER: laboratory biomarker analysis|OTHER: mass spectrometry|OTHER: medical chart review
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Evaluate the Safety, Tolerability, and Immunogenicity of V114 Followed by PNEUMOVAX™23 in Adults Infected With Human Immunodeficiency Virus (HIV) (V114-018)
Status: COMPLETED
Conditions: Pneumococcal Infections
Interventions: BIOLOGICAL: V114|BIOLOGICAL: Prevnar 13™|BIOLOGICAL: PNEUMOVAX™23
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Topical Glaucoma Therapy on Tear Film Stability in Healthy Subjects
Status: TERMINATED
Conditions: Healthy
Interventions: DRUG: Timoptic® 0.5%|DRUG: Timophtal sine® 0.5%|DEVICE: Genteal HA®|DEVICE: Hylo-Comod®|DEVICE: Thealoz®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect of Dexmedetomidine for Emergence Cough
Status: COMPLETED
Conditions: Cough
Interventions: DRUG: Dexmedetomidine|DRUG: Remifentanil|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Use of Touch and no Touch Guide-wire Techniques for Deep Biliary Cannulation: the TNT Study
Status: COMPLETED
Conditions: Biliary Tract Diseases
Interventions: PROCEDURE: Guide-wire cannulation|PROCEDURE: Sphincterotome assisted guide-wire cannulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Study of Azacitidine in Participants With International Prognostic Scoring System (IPSS) Intermediate-2 and High-risk Myelodysplastic Syndromes (MDS), or Chronic Myelomonocytic Leukemia (CMML), or Acute Myeloid Leukemia (AML)
Status: COMPLETED
Conditions: Myelodysplastic Syndromes|Leukemia, Myelomonocytic, Chronic|Leukemia, Myeloid, Acute
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Remimazolam and Propofol for Recovery of Ambulatory Upper Airway Surgery
Status: RECRUITING
Conditions: Laryngeal Disease|Pharyngeal Diseases|Oral Cavity Disease|Nasal Disease
Interventions: DRUG: Remimazolam|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Anti-gravity Treadmill Exercise in Stress Myocardial Perfusion Imaging
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DEVICE: Antigravity treadmill (Alter-G)|DEVICE: Conventional treadmill/regadenoson
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Vitamin D Supplementation on Health of Low Birth Weight Infants
Status: COMPLETED
Conditions: Vitamin D Deficiency
Interventions: DRUG: Vitamin D3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Neurobiology of Language Recovery in Aphasia: Natural History and Treatment-Induced Recovery
Status: COMPLETED
Conditions: Aphasia|Dysgraphia|Anomia|Agrammatism|Stroke
Interventions: BEHAVIORAL: Treatment Focusing on Naming Objects|BEHAVIORAL: Treatment Focusing on Improving Spelling Abilities|BEHAVIORAL: Treatment Focusing on Improving Sentence Processing|BEHAVIORAL: No Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Safety and Efficacy of Avadomide (CC-122) Combined With RCHOP for Newly-diagnosed DLBCL With Poor Risk Factors
Status: COMPLETED
Conditions: Diffuse B-Cell Lymphoma
Interventions: DRUG: Avadomide (CC-122)|DRUG: Rituximab|DRUG: Cyclophosphamide 750mg/m2 by IV infusion|DRUG: Vincristine|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Plasma Exchange With Albumin in Patients With Amyotrophic Lateral Sclerosis
Status: COMPLETED
Conditions: Amyotrophic Lateral Sclerosis
Interventions: BIOLOGICAL: Albumin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ESWT vs Cryo-US Therapy in the Treatment of Chronic Lateral Epicondylitis: One Year Follow up Study
Status: COMPLETED
Conditions: Tendinopathy
Interventions: DEVICE: MODULITH® SLK, STORZ MEDICAL AG, Switzerland|DEVICE: Cryoultrasound™, Medisport S.r.l., Italy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity Trial of an Oral SARS-CoV-2 Vaccine (VXA-CoV2-1) for Prevention of COVID-19 in Healthy Adults and Boost (VXA-CoV2-1.1-S) at 1 Year Post Initial Vaccination in Subset of Subjects
Status: COMPLETED
Conditions: Covid19
Interventions: BIOLOGICAL: VXA-CoV2-1
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Leveraging EEG for Antidepressant Prediction With Sertraline and Escitalopram
Status: WITHDRAWN
Conditions: Major Depressive Disorder
Interventions: DRUG: Sertraline|DRUG: Escitalopram
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Virtual Reality, Mood, and Sedentary Behaviour After Stroke
Status: TERMINATED
Conditions: Stroke|Stroke, Ischemic|Stroke Hemorrhagic|Stroke, Lacunar
Interventions: BEHAVIORAL: Virtual reality gaming program (VR-gaming program)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Activity of Trabectedin or Gemcitabine + Docetaxel in Uterine Leiomyosarcoma
Status: COMPLETED
Conditions: Leiomyosarcoma
Interventions: DRUG: gemcitabine + docetaxel|DRUG: trabectedin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SHR-1210 Combined With Apatinib Mesylate in the Perioperative Treatment of Hepatocellular Carcinoma
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Apatinib Combined With SHR-1210 Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Effects of IMT Vs EMT Along With AIT in COPD Patients
Status: COMPLETED
Conditions: COPD
Interventions: OTHER: Group A (Inspiratory Muscles Training + Aerobic Interval Training)|OTHER: Group B (Expiratory Muscles Training +Aerobic Interval Training)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Secondary Study Evaluating Aqueduct's Smart External Drain (SED)
Status: TERMINATED
Conditions: Hydrocephalus|Hydrocephalus in Children|Tumor, Brain|Subarachnoid Hemorrhage
Interventions: DEVICE: Smart External Drain - SED
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: XELOX +Bev +Tislelizumab for First-line Treatment of MSS/pMMR RAS-mutated mCRC
Status: RECRUITING
Conditions: Tislelizumab|Bevacizumab|Oxaliplatin|Capecitabine|MSS/pMMR|Metastatic Colorectal Cancer (mCRC)|RAS-mutated|First-Line
Interventions: DRUG: Tislelizumab+Bevacizumab+Oxaliplatin+Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of a Mindfulness-based Intervention on Well-being and Mental Health of Elementary School Children
Status: COMPLETED
Conditions: Mindfulness-based Intervention|Elementary School Children|Mental Health Wellness 1
Interventions: BEHAVIORAL: Mindfulness-based intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Safety and Effectiveness of Topiramate Compared to Placebo in the Treatment of Patients With Bipolar I Disorder
Status: COMPLETED
Conditions: Bipolar Disorder|Affective Disorders, Psychotic|Mood Disorders|Mental Disorders
Interventions: DRUG: Topiramate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Incretin Axis in Type 1 Diabetes Mellitus
Status: UNKNOWN
Conditions: Type 1 Diabetes Mellitus
Interventions: DRUG: Linagliptin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Tanezumab in Osteoarthritis of the Knee
Status: COMPLETED
Conditions: Arthritis|Osteoarthritis
Interventions: BIOLOGICAL: tanezumab|BIOLOGICAL: tanezumab|BIOLOGICAL: tanezumab|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Efficacy and Safety of AZD4831 in Participants With Heart Failure With Left Ventricular Ejection Fraction > 40%
Status: COMPLETED
Conditions: Heart Failure With Preserved Ejection Fraction
Interventions: DRUG: AZD4831|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of Frexalimab, SAR442970, or Rilzabrutinib in Participants Aged 16 to 75 Years With Primary Focal Segmental Glomerulosclerosis or Minimal Change Disease
Status: NOT_YET_RECRUITING
Conditions: Focal Segmental Glomerulosclerosis|Glomerulonephritis Minimal Lesion
Interventions: DRUG: frexalimab|DRUG: SAR442970|DRUG: rilzabrutinib|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Pharamcogenomic Study for Isoniazid According to NAT2 Polymorphism Status
Status: COMPLETED
Conditions: Tuberculosis|Drug-Induced Liver Injury|Adverse Drug Event
Interventions: DRUG: Isoniazid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: OBE001 Phase 2 Dose-finding Study Versus Placebo in Women Undergoing Embryo Transfer in the Context of IVF-ICSI
Status: COMPLETED
Conditions: Infertility
Interventions: DRUG: OBE001 dose 1|DRUG: OBE001 dose 2|DRUG: OBE001 dose 3|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Efficacy and Safety of A High Molecular Weight, Natural Hyaluronic Acid Vaginal Gel in Women With Genitourinary Syndrome of Menopause
Status: COMPLETED
Conditions: Menopause Syndrome
Interventions: DEVICE: Vaginal Moisturizing Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Safety and Tolerability of Single Ascending Doses of REGN1033(SAR391786)
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: REGN1033(SAR391786)|DRUG: REGN1033(SAR391786)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Impact of Pain Scores on Intrauterine Lidocaine Versus Normal Saline Infusion at the Time of IUD Placement
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Lidocaine|DRUG: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety Study of GlaxoSmithKline (GSK) Biologicals' Combined Measles-mumps-rubella (MMR) Vaccine in Subjects Four to Six Years of Age
Status: COMPLETED
Conditions: Measles-Mumps-Rubella
Interventions: BIOLOGICAL: Priorix|BIOLOGICAL: M-M-R II|BIOLOGICAL: Kinrix|BIOLOGICAL: ProQuad
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of MK-6552 and the Effect of Food in Healthy Participants (MK-6552-006)
Status: NOT_YET_RECRUITING
Conditions: Healthy
Interventions: DRUG: MK-6552
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Assessing the Impact of "Super-whey" vs. Isonitrogenous Whey on Muscle Protein Synthesis
Status: COMPLETED
Conditions: Sarcopenia
Interventions: DIETARY_SUPPLEMENT: Super-Whey protein|DIETARY_SUPPLEMENT: Isonitrogenous whey protein
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Influence of a Liquid Oat Bran Product on Blood Glucose in Patients With Poorly Controlled Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Obesity|Overweight|Metabolic Syndrome
Interventions: OTHER: active product|OTHER: reference product
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Pharmacokinetic and Safety Trial of Emraclidine in Participants With Renal Impairment Compared With Participants With Normal Renal Function
Status: RECRUITING
Conditions: Renal Impairment
Interventions: DRUG: Emraclidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Effectiveness of Ertapenem Versus Ceftriaxone/Metronidazole in the Treatment of Intra-abdominal Infections in Adults (0826-802)
Status: COMPLETED
Conditions: Intra-abdominal Infection
Interventions: DRUG: Comparator: ceftriaxone sodium / Duration of Treatment: 8 Weeks|DRUG: MK0826, /Duration of Treatment : 8 Weeks|DRUG: Comparator: metronidazole / Duration of Treatment: 8 Weeks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Membranous Nephropathy-associated Serological Antibody Predict the Prognosis of Idiopathic Membranous Nephropathy
Status: TERMINATED
Conditions: Idiopathic Membranous Nephropathy
Interventions: DIAGNOSTIC_TEST: PLA2R|DIAGNOSTIC_TEST: TSHD7A
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of an Anterior Chamber Infusion System on Trabeculectomy Outcomes
Status: WITHDRAWN
Conditions: Glaucoma
Interventions: PROCEDURE: Trabeculectomy with anterior chamber infusion system|PROCEDURE: Trabeculectomy without anterior chamber infusion system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Benefit of Follicular Flushing During Oocyte Retrieval for Poor Responder Patient in an Assisted Reproductive Technology Program
Status: COMPLETED
Conditions: Infertility, Female|Ovarian Insufficiency
Interventions: PROCEDURE: Direct aspiration needle Echo tip® Cook® single Lumen and Follicular flushing with double lumen needle Echo tip® Cook® Double Lumen Aspiration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: OTHER
Clinical trial: Radiotherapy Followed by Adjuvant Chemotherapy in NK/T-cell Lymphoma
Status: UNKNOWN
Conditions: Extranodal NK/T-cell Lymphoma, Nasal Type
Interventions: DRUG: Radiotherapy followed by chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Influence of LMA Cuff Pressure on Gastric Insufflation Assessed by Ultrasound in Pediatric Patient
Status: UNKNOWN
Conditions: Aspiration
Interventions: BEHAVIORAL: lower pressure|BEHAVIORAL: higher pressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Stereotactic Body Radiation Therapy in Treating Patients With Metastatic or Recurrent Kidney Cancer
Status: TERMINATED
Conditions: Metastatic Renal Cell Cancer|Recurrent Renal Cell Carcinoma|Stage IV Renal Cell Cancer
Interventions: RADIATION: Stereotactic Body Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimizing Pazopanib Exposure in RCC Patients
Status: TERMINATED
Conditions: Locally Advanced Renal Cell Carcinoma|Metastatic Renal Cell Carcinoma
Interventions: DRUG: Pazopanib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Cardio-Oncology Rehabilitation Exercise for Women With Breast Cancer and Treatment Related Cardiotoxicity
Status: TERMINATED
Conditions: Breast Cancer|Left Ventricular Dysfunction|Heart Failure, Systolic
Interventions: OTHER: Exercise Rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Feasibility Study of the Safety and Efficacy of Anakinra in Heart Failure With Preserved Ejection Fraction
Status: COMPLETED
Conditions: Heart Failure
Interventions: DRUG: Anakinra|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Pharmacokinetics, Safety, and Tolerability of ZONISADE in Children 1 Month to 17 Years of Age With Partial-onset Seizures
Status: NOT_YET_RECRUITING
Conditions: Seizures|Seizures, Focal|Seizure, Partial Onset|Seizure Disorder, Partial|Seizure, Partial|Epilepsies, Partial|Epilepsy
Interventions: DRUG: Zonisamide Oral Product
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fibrosis Reduction in Non Alcoholic Steatohepatitis
Status: ACTIVE_NOT_RECRUITING
Conditions: NASH With Fibrosis|Weight Loss|Bariatric Surgery Candidate
Interventions: PROCEDURE: roux -en-y- gastric bypass|DIETARY_SUPPLEMENT: intensive life style modification
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy and Tolerability Study of Betahistine to Ameliorate Antipsychotic Associated Weight Gain
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder|Schizophreniform Disorder|Bipolar I Disorder|Bipolar II|Bipolar NOS(Not Otherwise Specified)|Psychotic Disorder Not Otherwise Specified|Autism Spectrum Disorder
Interventions: DRUG: Betahistine|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 4DFlow Magnetic Resonance Imaging in Patients With Pulmonary Hypertension Associated With Congenital Heart Disease
Status: UNKNOWN
Conditions: Congenital Heart Disease|Pulmonary Arterial Hypertension
Interventions: OTHER: 4D Flow magnetic resonance imagery|PROCEDURE: Cardiac catheterization
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Time-restricted Feeding Improves Basal Fat Oxidation and Body Composition But Not Fat Oxidation During Exercise
Status: COMPLETED
Conditions: Dietary Exposure
Interventions: OTHER: Intermittent Fasting: Time Restricted Feeding During 6 Weeks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Levetiracetam Versus Carbamazepine in Post-Stroke Late Onset Crisis
Status: UNKNOWN
Conditions: Epileptic Seizures|Stroke
Interventions: DRUG: Levetiracetam|DRUG: Carbamazepine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neurohormonal Parameters in Hypertrophic Cardiomyopathies
Status: COMPLETED
Conditions: 1- Primary (Sarcomeric) Hypertrophic Cardiomyopathy|2- Obstructive Hypertrophic Cardiomyopathy|3- Non Obstructive Hypertrophic Cardiomyopathy
Interventions: OTHER: blood sample collection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Drug Coated Balloon Compared to Bare Metal Stent for de Novo Coronary Artery Lesions
Status: COMPLETED
Conditions: Stable Angina|Unstable Angina
Interventions: DEVICE: Drug Coated Balloon|DEVICE: Bare Metal Stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of Navicixizumab in Patients With Platinum Resistant Ovarian Cancer
Status: UNKNOWN
Conditions: Ovarian Cancer|Fallopian Tube Cancer|Primary Peritoneal Carcinoma
Interventions: DRUG: navicixizumab|DEVICE: Xerna™ TME Panel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Primary Irritation Patch Test (PIPT) Study Conducted at NovoBliss Research for Shared Panel
Status: NOT_YET_RECRUITING
Conditions: Healthy
Interventions: OTHER: Peptide complexed HA Age Defying Gel with Vitamin C & Niacinamide|OTHER: Peptide complexed HA Age Defying Gel with Natural Extracts|OTHER: Peptide complexed HA Age Defying Gel with Vitamin C & Natural Extracts|OTHER: 1% w/v Sodium Lauryl Sulphate (SLS) solution|OTHER: Sodium chloride (Isotonic Saline Solution) Injection IP 0.9 % w/v
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Broad One Health Endectocide-based Malaria Intervention in Africa (BOHEMIA)
Status: ACTIVE_NOT_RECRUITING
Conditions: Malaria
Interventions: DRUG: Albendazole Pill|DRUG: Ivermectin Pill|DRUG: Ivermectin Injectable Product
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aronia, Cognition, and Eye Health (ACE)
Status: RECRUITING
Conditions: Cognitive Function
Interventions: DIETARY_SUPPLEMENT: Aronia supplementation|DIETARY_SUPPLEMENT: Cellulose supplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Continuous APL-1202 Treatment in Subjects With High-Risk Non-Muscle-Invasive Bladder Cancer (NMIBC) Relapsed From Intravesical Chemo/BCG Therapy
Status: COMPLETED
Conditions: Non-muscle Invasive Bladder Cancer
Interventions: DRUG: APL-1202 treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Laser Treatment With Clobetasol Therapy in Patients With Lichen Sclerosus
Status: RECRUITING
Conditions: Lichen Sclerosus
Interventions: DEVICE: Treatment with Monalisa Glide Laser|DRUG: Treatment with Clobetasol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Vaginal Health Trial
Status: COMPLETED
Conditions: Atrophy of Vagina|Menopause|Dyspareunia (Female)
Interventions: DRUG: Vagifem|DEVICE: Replens|OTHER: Placebo tablet|OTHER: Placebo gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation Ultrasound Elasticity/Tissue Strain-Hardening Imaging for Prostate Cancer Patients Undergoing Radical Prostatectomy
Status: TERMINATED
Conditions: Prostate Cancer
Interventions: PROCEDURE: Tissue Elastography Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Predictive Properties of Myocardial Fibrosis Biomarkers on the Outcome of Atrial Fibrillation Ablation
Status: RECRUITING
Conditions: Women and Men Over 18 Years Old|AF Ablation (ECS recommendation2020&ACS2014) Either for Paroxysmal AF Unresponsive to Anti-arrhythmic Treatment Either for Persisting Symptomatic AF|Able to Give His Non Opposition to Participate to the Study
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effectiveness of Familiar Voices and Nature Sounds Among Critically Ill Comatose Patients
Status: RECRUITING
Conditions: Coma|Critical Illness|Unconsciousness
Interventions: BEHAVIORAL: Familiar voice|BEHAVIORAL: Nature sounds|BEHAVIORAL: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of Penetrating Keratoplasty and Deep Lamellar Keratoplasty With the Big Bubble Technique for Keratoconus
Status: UNKNOWN
Conditions: Keratoconus
Interventions: PROCEDURE: keratoplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Initial Staging of Lobular Breast Carcinoma: Head to Head Comparison of 68Ga-FAPI-46 and 18F-FDG PET/CT
Status: RECRUITING
Conditions: Lobular Breast Carcinoma
Interventions: DIAGNOSTIC_TEST: 68Ga-FAPI-46 PET scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Phase II Trial of ZD1839 (Iressa) in Patients With Nonresectable Adrenocortical Carcinoma (ACC)
Status: COMPLETED
Conditions: Nonresectable Adrenocortical Carcinoma
Interventions: DRUG: Iressa (ZD1839)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Tirellizumab Combined With Chemotherapy Monotherapy for Non-small Cell Lung Cancer
Status: NOT_YET_RECRUITING
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: Tirelizumab；Chemotherapy monotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility Trial Evaluating Efficacy and Safety of Solitaire™ Thrombus Retrieval Device in the Management of Refractory Thrombus in Patients With Acute Coronary Syndrome
Status: UNKNOWN
Conditions: Refractory Thrombus in Patients With Acute Coronary Syndrome
Interventions: DEVICE: Solitaire™ thrombus retrieval device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Performance Study of SONA Saliva C-19 Rapid Test
Status: TERMINATED
Conditions: Covid19|Sars-CoV-2 Infection|Corona Virus Infection
Interventions: DIAGNOSTIC_TEST: Sona Saliva C-19 Rapid Test
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Preoperative Inspiratory Muscle Training Effects on the Perioperative Inflammatory Reaction in Cardiac Surgery.
Status: COMPLETED
Conditions: Thoracic Surgery|Prehabilitation|Respiratory Therapy
Interventions: OTHER: Prehabilitation with inspiratory muscle training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Phase 3 Study of BGJ398 (Oral Infigratinib) in First Line Cholangiocarcinoma With FGFR2 Gene Fusions/Translocations
Status: TERMINATED
Conditions: Advanced Cholangiocarcinoma|FGFR2 Gene Mutation
Interventions: DRUG: BGJ398|DRUG: Gemcitabine|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multi-Centre Study on the Performance of the Ponto BHX Implant System (in Adult Patients)
Status: COMPLETED
Conditions: Hearing Loss
Interventions: OTHER: Abbreviated Profile of Hearing Aid Benefit (APHAB)|OTHER: Glasgow Benefit Inventory (GBI)|OTHER: Additional follow-up visits after surgery
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety Study of Finafloxacin Used in Helicobacter Pylori Infected Patients
Status: COMPLETED
Conditions: Gram-Negative Bacterial Infections|Helicobacter Infections|Dyspepsia
Interventions: DRUG: Finafloxacin + Amoxicillin|DRUG: Finafloxacin + Esomeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dydrogesterone, Cetrorelix Acetate and Triptorelin in Intra Cytoplasmic Sperm Injection Outcomes
Status: RECRUITING
Conditions: IVF
Interventions: DRUG: Dydrogesterone|DRUG: Cetrorelix acetate|DRUG: Triptorelin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Evaluate the Efficacy and Safety of CAEP-01 on Eye Strain in Children With Heavy Screen Use
Status: COMPLETED
Conditions: Vision Disorders
Interventions: OTHER: CAEP-01|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Effectiveness of Non-surgical Management in Rotator Cuff Calcific Tendinopathy (THE EFFECT TRIAL)
Status: RECRUITING
Conditions: Rotator Cuff Tendinosis|Rotator Cuff Injuries|Shoulder Tendinitis|Calcific Shoulder Tendinitis|Calcification Tendon|Calcific Tendinitis|Shoulder Pain
Interventions: PROCEDURE: Exercise Therapy|PROCEDURE: Extracorporeal Shockwave Therapy|PROCEDURE: Ultrasound-Guided Percutaneous Irrigation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Study of Punctal Placement of the Latanoprost Punctal Plug Delivery System (L-PPDS)
Status: COMPLETED
Conditions: Open-Angle Glaucoma|Ocular Hypertension
Interventions: DRUG: Latanoprost
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Atezolizumab and Paclitaxel Versus Placebo and Paclitaxel in Participants With Previously Untreated Locally Advanced or Metastatic Triple Negative Breast Cancer (TNBC)
Status: COMPLETED
Conditions: Triple-Negative Breast Cancer
Interventions: DRUG: Atezolizumab (MPDL3280A), an engineered anti-PDL1 antibody|DRUG: Atezolizumab Placebo|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: As a Second-line Treatment for Metastatic Gastric Adenocarcinoma Patients, the Safety and Effective of Vactosertib Administration in Combination With Paclitaxel+Ramucirumab is Evaluated, and a Phase 2a Clinical Trial to Biomarkers
Status: NOT_YET_RECRUITING
Conditions: Gastric Cancer
Interventions: DRUG: Vactosertib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial of TT223 in Patients With Type 2 Diabetes Who Are Taking Metformin and/or Thiazolidinedione
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: TT223 with Metformin and/or TZD|DRUG: Placebo with Metformin and/or TZD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Piiloset Trehalose Emulsion Eye Drop Study in Moderate or Severe Dry Eye
Status: COMPLETED
Conditions: Dry Eye Syndrome
Interventions: DEVICE: Piiloset Trehalose Emulsion Eye Drops|DEVICE: Control Eye Drops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Study of Topically Applied Veregen 15% Compared With Oral Intake of Green Tea Beverage
Status: COMPLETED
Conditions: Genital Warts|Perianal Warts
Interventions: DRUG: Polyphenon E (Veregen) 15% ointment|OTHER: Green Tea Beverage with defined catechin content
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of LNG-IUS for Treatment of Non-atypical Endometrial Hyperplasia in Perimenopausal Women
Status: COMPLETED
Conditions: Endometrial Hyperplasia
Interventions: DRUG: LNG-IUS; Mirena; Bayer Schering Pharma Oy, Finland|DRUG: Norethisterone Acetate tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Butylphthalide on Dynamic Cerebral Autoregulation in Patients With Acute Ischemic Stroke.
Status: COMPLETED
Conditions: Acute Ischemic Stroke
Interventions: DRUG: butylphthalide(NBP)|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Performance and Occlusal Wear of Low Shrinkage Giomer Compared to Nanohybrid Resin Composite
Status: NOT_YET_RECRUITING
Conditions: Caries Class II
Interventions: DRUG: Beautifil II LS (Low-Shrinkage)|DRUG: 3M Filtek Z250 XT Universal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Drug-Drug Interaction Study of Vesatolimod in Adults With HIV-1 Who Have Very Low or Undetectable Virus Levels
Status: TERMINATED
Conditions: Human Immunodeficiency Virus Type 1 (HIV-1) Infection
Interventions: DRUG: Vesatolimod|DRUG: Cobicistat|DRUG: Voriconazole|DRUG: Rifabutin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Camrelizumab in Combination With Radiotherapy for Neoadjuvant Esophageal Carcinoma.
Status: UNKNOWN
Conditions: Esophageal Neoplasm|Immunotherapy|Radiotherapy
Interventions: DRUG: Camrelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics and Safety of Intravenous Posaconazole (MK-5592) in Chinese Participants at High Risk for Invasive Fungal Infections (MK-5592-120)
Status: COMPLETED
Conditions: Fungal Infection
Interventions: DRUG: Posaconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Radiotherapy vs Neck Dissection for Clinical T1/2N0 Supraglottic Cancer
Status: NOT_YET_RECRUITING
Conditions: Supraglottic Cancer
Interventions: RADIATION: Radiotherapy|PROCEDURE: Selective neck dissection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low-back Pain During Pregnancy and Its Psycho-social Implications
Status: UNKNOWN
Conditions: Pregnancy Related|Low Back Pain|Pelvic Girdle Pain
Interventions: OTHER: Osteopathic manipulative treatment|OTHER: Usual care|OTHER: Mindfulness|OTHER: Yoga|OTHER: Clinical nutrition|OTHER: Coaching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Lipid Modifying Drugs on HDL Function in Patients With Hyperlipidemia
Status: COMPLETED
Conditions: Hyperlipidemia
Interventions: DRUG: Atorvastatin 20 mg|DRUG: Cholestyramine 8 g|DRUG: Omega-3 2g|DRUG: Concurrent with Atorvastatin 5 mg + Ezetimibe 10 mg|BEHAVIORAL: Lifestyle modification
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Use of CBCT-based Tooth Replica in Tooth Autotransplantation to Improve the Outcome of Tooth Replacement in Children
Status: COMPLETED
Conditions: Increase Success Rate of Tooth Transplantation
Interventions: OTHER: stereolithography tooth replica
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antigen Specific Adoptive T Cell Therapy for Adenovirus Infection After Hematopoietic Stem Cell Transplantation
Status: RECRUITING
Conditions: Allogeneic Hematopoietic Stem Cell Transplantation
Interventions: BIOLOGICAL: IFN-gamma-secreting HAdV antigen specific T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Global, Postmarketing Observational Safety Study to Evaluate the Safety and Tolerability of Fycompa (Perampanel) as Add-on Therapy in Epilepsy Patients Aged Greater Than or Equal to 12 Years
Status: COMPLETED
Conditions: Epilepsy
Interventions: DRUG: Perampanel
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Cardioneuroablation: Fragmented Atrial Potentials, Intracardiac Echocardiography and Computed Tomography
Status: RECRUITING
Conditions: Syncope, Vasovagal
Interventions: PROCEDURE: Cardioneuroablation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Electronic Training of Elderly Depression With Cognitive Impairment
Status: COMPLETED
Conditions: Geriatric Depression|Cognitive Impairment
Interventions: DRUG: Selective Serotonin Reuptake Inhibitor（SSRIs，Fluoxetine, paroxetine, fluvoxamine, sertraline, citalopram, escitalopram）
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PRELUDE:Study to Investigate the Prevention of Relapse in Lymphoma Using Daily Enzastaurin
Status: COMPLETED
Conditions: Non Hodgkin Lymphoma
Interventions: DRUG: enzastaurin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Japanese Phase 1 Multiple Ascending Dose Study
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: BMS-823778|DRUG: BMS-823778|DRUG: BMS-823778|DRUG: BMS-823778|DRUG: Placebo matching with BMS-823778
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intervention on Bone Health in Wheelchair Users
Status: RECRUITING
Conditions: Bone Loss|Spinal Cord Injuries|Cerebral Palsy|Spina Bifida|Dysmelia|Amputation
Interventions: OTHER: Bone-specific strength training|DIETARY_SUPPLEMENT: Nutrition optimalisation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety, Pharmacokinetics, and Preliminary Efficacy of BYON4413 in Acute Myeloid Leukemia and Myelodysplastic Neoplasms.
Status: RECRUITING
Conditions: Relapsed / Refractory AML|Relapsed / Refractory MDS
Interventions: DRUG: BYON4413
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Influence of Citric Acid Bone Surface Etching and Bone Defect Fill on GCF BMP-2 Release Profile
Status: COMPLETED
Conditions: Intrabony Periodontal Defect
Interventions: DRUG: Citric acid|DRUG: Control Test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: TDM Guided Early Optimization of ADAL in Crohn's Disease
Status: RECRUITING
Conditions: Crohn Disease|Drug Monitoring|Inflammatory Bowel Diseases
Interventions: BIOLOGICAL: Adalimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Test How BI 765063 and BI 770371 Are Taken up in Tumours of People With Different Types of Advanced Cancer Who Are Also Taking Ezabenlimab
Status: RECRUITING
Conditions: Carcinoma, Squamous Cell of Head and Neck (HNSCC)|Melanoma|Non-small Cell Lung Cancer (NSCLC)
Interventions: DRUG: BI 765063|DRUG: Ezabenlimab|DRUG: [89Zr]Zr- BI 765063|DRUG: BI 770371|DRUG: [89Zr]Zr- BI 770371
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Releasing of Inflammatory Mediators During Retreatment of Root Canals
Status: COMPLETED
Conditions: Inflammatory Response|Root Canal Infection
Interventions: OTHER: Protaper Universal Retreatment|OTHER: Reciproc|OTHER: XP-Endo finisher R
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Holographic Standardized Patient
Status: NOT_YET_RECRUITING
Conditions: Medical Emergencies|Educational Problems|Simulation of Physical Illness
Interventions: DEVICE: HoloSIM Software via Hololens 2|OTHER: Training by Mannequin Based Simulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: PBI-MST-01(NCT04541108) Substudy TAK-02: Intratumoral Microdosing of TAK-676 in HNSCC
Status: COMPLETED
Conditions: Head and Neck Squamous Cell Carcinoma
Interventions: DRUG: TAK-676|DRUG: Carboplatin|DRUG: 5-FU|DRUG: Paclitaxel|COMBINATION_PRODUCT: TAK-676 + Carboplatin|COMBINATION_PRODUCT: Carboplatin + Paclitaxel|COMBINATION_PRODUCT: Carboplatin + 5-FU|COMBINATION_PRODUCT: TAK-676 + Carboplatin + 5-FU|COMBINATION_PRODUCT: TAK-676 + Carboplatin + Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Can the Use of a Next Generation Partograph Improve Neonatal Outcomes? (PICRINO)
Status: NOT_YET_RECRUITING
Conditions: Neonatal Complication|Labor (Obstetrics)--Complications
Interventions: OTHER: WHOs Labour care guide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multicenter Study for Pediatric Subjects Evaluating Pharmacokinetics and Safety of EXPAREL
Status: COMPLETED
Conditions: Postoperative Pain Management
Interventions: DRUG: Exparel|DRUG: 0.5% Bupivacaine HCl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hyperbaric Oxygen Therapy Compared to Pharmaceutical in Fibromyalgia With Emotional Trauma
Status: COMPLETED
Conditions: Fibromyalgia|Emotional Trauma
Interventions: DEVICE: Hyperbaric oxygen therapy (HBOT) treatment|DRUG: Cymbalta / Lyrica - Drug treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Osimertinib Combined With Anlotinib in EGFR T790M Mutated NSCLC Patients With Progression on Osimertinib Treatment
Status: TERMINATED
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: osimertinib mesylate tablets and anlotinib hydrochloride capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness Study of Human Papilloma Virus (HPV) Vaccines to Prevent Recurrence of Genital Warts
Status: ACTIVE_NOT_RECRUITING
Conditions: Genital Warts
Interventions: BIOLOGICAL: Quadrivalent HPV vaccine|BIOLOGICAL: Hepatitis B vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Trial of SHR0410 Injection in Postsurgical Pain Management
Status: UNKNOWN
Conditions: Postsurgical Pain
Interventions: DRUG: SHR0410 Injection|DRUG: Placebo for SHR0410 Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Multicenter Randomized Trial Comparing Antiglide and Lateral Plate Fixation in Ankle Fractures
Status: COMPLETED
Conditions: Ankle Injuries
Interventions: DEVICE: Antiglide Plate|DEVICE: Lateral Plate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Regulation of KATP Channels and Na+/K+ ATPase in Relation to Fatigue Development
Status: COMPLETED
Conditions: Insulin Resistance
Interventions: DRUG: Placebo|DRUG: Nicorandil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE