pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Irreversible Electroporation + Nivolumab for Patients With Metastatic Pancreatic Cancer
Status: TERMINATED
Conditions: Pancreas Cancer
Interventions: DRUG: Nivolumab|DEVICE: Irreversible electroporation (IRE)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Psychobiological Interventions in Pregnancy
Status: NOT_YET_RECRUITING
Conditions: Pregnancy Complications|Mental Health Issue|Depression, Anxiety|Pregnancy, High Risk|Biological Clock Disturbance
Interventions: BEHAVIORAL: Step count goal|DEVICE: Actigraph watch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Mobile Device App to Improve Adherence to an Enhanced Recovery Program for Colorectal Surgery
Status: COMPLETED
Conditions: Colorectal Disorders
Interventions: DEVICE: Mobile application|OTHER: Control.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multiple Treatment Session Study to Assess GSK2398852 Administered Following and Along With GSK2315698
Status: TERMINATED
Conditions: Amyloidosis
Interventions: DRUG: GSK2315698 (CPHPC)|BIOLOGICAL: GSK2398852 (anti-SAP mAb)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ranolazine Implantable Cardioverter-Defibrillator Trial
Status: COMPLETED
Conditions: Ischemic Cardiomyopathy|Nonischemic Cardiomyopathy|Heart Failure
Interventions: DRUG: Ranolazine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Utility and Usability of ActivSight™ Laser Speckle Imaging in Visualization of Tissue Perfusion and Blood Flow During Esophageal Surgery in Humans
Status: RECRUITING
Conditions: Esophagus Cancer|Esophageal Cancer|Esophageal Neoplasms|Esophageal Diseases|Esophageal Adenocarcinoma|Esophageal Squamous Cell Carcinoma|Esophagus SCC|Esophagus Tumor|Esophagus Adenocarcinoma|Esophagus Neoplasm
Interventions: DEVICE: ActivSight
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: RC18 in Patients With Relapsing Remitting Multiple Sclerosis：a Phase II Trial
Status: RECRUITING
Conditions: Multiple Sclerosis, Relapsing-Remitting
Interventions: BIOLOGICAL: RC18 160mg|BIOLOGICAL: RC18 240mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EMuNI Project: Multiple Nonpharmacological Interventions
Status: COMPLETED
Conditions: Lifestyle Risk Reduction
Interventions: DIETARY_SUPPLEMENT: Nutritional supplementation|BEHAVIORAL: Educational training|BEHAVIORAL: Counselling on a brain-healthy diet|BEHAVIORAL: Physical exercise training|BEHAVIORAL: Computerized cognitive training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Dysphagia and Ineffective Esophageal Motility With Prucalopride: A Pilot Study
Status: COMPLETED
Conditions: Ineffective Esophageal Motility|Dysphagia
Interventions: DRUG: Prucalopride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nilotinib Plus Pegylated Interferon-α2b in CML
Status: TERMINATED
Conditions: Chronic Myeloid Leukemia
Interventions: DRUG: Nilotinib|DRUG: Pegylated interferon α-2b
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: LSD Base and LSD Tartrate Bioequivalence and Bioavailability in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Lysergic Acid Diethylamide Base oral drinking solution|DRUG: Lysergic Acid Diethylamide Base solid orodispersible film|DRUG: Lysergic Acid Diethylamide Tartrate oral drinking solution|DRUG: Lysergic Acid Diethylamide Tartrate intravenous administration|OTHER: LSD Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of the Effect of Reiki on Surgical Fear and Anxiety in Laparoscopic Cholecystectomy; Randomized Controlled Study
Status: RECRUITING
Conditions: Supportive Care
Interventions: OTHER: Reiki/Sham Reiki
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Oral Self Medication Versus IV Administration of Pain Killers After Caesarian Delivery
Status: COMPLETED
Conditions: Caesarian Section
Interventions: DRUG: Acetaminophen, ketoprofen, morphine|DRUG: Acetaminophen, ketoprofen,morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SGLT2 Inhibition and Left Ventricular Mass
Status: TERMINATED
Conditions: Diabetes Mellitus Type 2
Interventions: DRUG: Empagliflozin|DRUG: Glimepiride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cholesterol Lowering and Residual Risk in Diabetes, Type 1
Status: RECRUITING
Conditions: Type 1 Diabetes
Interventions: DRUG: Evolocumab Cartridge|DRUG: Atorvastatin Calcium Tablets|DRUG: Ezetimibe Tablets|DRUG: 18F-FDG|DEVICE: Angiocatheter 20IV|DEVICE: J-Wire|DEVICE: GlycoCheck Glycocalyx Measurement Software
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Nivolumab in Treating Patients With Relapsed or Refractory Peripheral T-cell Lymphoma
Status: TERMINATED
Conditions: Blastic Plasmacytoid Dendritic Cell Neoplasm|Hepatosplenic T-Cell Lymphoma|HTLV-1 Infection|NK-Cell Lymphoma, Unclassifiable|Primary Systemic Anaplastic Large Cell Lymphoma, ALK-Negative|Recurrent Adult T-Cell Leukemia/Lymphoma|Recurrent Anaplastic Large Cell Lymphoma|Recurrent Angioimmunoblastic T-cell Lymphoma|Recurrent Enteropathy-Associated T-Cell Lymphoma|Recurrent Mycosis Fungoides|Refractory Adult T-Cell Leukemia/Lymphoma|Refractory Anaplastic Large Cell Lymphoma|Refractory Angioimmunoblastic T-cell Lymphoma|Refractory Enteropathy-Associated T-Cell Lymphoma|Refractory Mycosis Fungoides|Refractory Nasal Type Extranodal NK/T-Cell Lymphoma|Refractory Peripheral T-Cell Lymphoma, Not Otherwise Specified
Interventions: OTHER: Laboratory Biomarker Analysis|BIOLOGICAL: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Extended Release Naltrexone for Treating Amphetamine Dependence in Iceland
Status: COMPLETED
Conditions: Amphetamine Dependence
Interventions: DRUG: VIVITROL injection and VIVITROL Placebo Injection , 24 weeks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Investigating Blood Concentrations Of Rosuvastatin When Co-administered With GW856553 In Healthy Men
Status: COMPLETED
Conditions: Atherosclerosis|Cardiovascular Disease
Interventions: DRUG: GW856553
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study of Oral Ixazomib Maintenance Therapy After Initial Therapy in Participants With Newly Diagnosed Multiple Myeloma Not Treated With Stem Cell Transplantation (SCT)
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Ixazomib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Home Sleep Apnea Machine in Evaluating Obstructive Sleep Apnea in Patients With Stage III-IV Head and Neck Cancer
Status: WITHDRAWN
Conditions: Locally Advanced Head and Neck Squamous Cell Carcinoma|Metastatic Head and Neck Squamous Cell Carcinoma
Interventions: DIAGNOSTIC_TEST: Monitoring Device|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Prevention of Post-operative Urinary Retention
Status: COMPLETED
Conditions: Urinary Retention|Urinary Tract Infections
Interventions: DRUG: Tamsulosin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluating the Therapeutic Effect of Scalp Acupuncture Treatment for Motor Dysfunction in Ischemic Stroke Patients
Status: UNKNOWN
Conditions: Ischemic Stroke|Hemiplegia
Interventions: DEVICE: Scalp Acupuncture Treatment|OTHER: Rehabilitation treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Exercise, Rest Breaks and Ergonomics Modification on Fatigue and MSK Discomfort in Static Workstation
Status: COMPLETED
Conditions: Musculoskeletal Pain
Interventions: OTHER: Exercise Without Rest Break|OTHER: Exercise With Rest Break|OTHER: Rest Break
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intensive Care Unit (ICU) Diary Project
Status: COMPLETED
Conditions: PTSD|Post ICU Syndrome
Interventions: OTHER: Diary (blank journal) plus PTSD psycho-education|OTHER: PTSD psycho-education alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Remifentanil and Hyperalgesia: Gradual Withdrawal Versus Immediate Discontinuation
Status: COMPLETED
Conditions: Anesthesia|Pain
Interventions: DRUG: Remifentanil|DRUG: NaCl 0.9%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Health Effects of Oat Bioactives (Betaglucan) in Human
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Effects of Oat and Oat Components on Cardiometabolic risk variables
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Application of 3D Printing Guide Plate in Percutaneous Disc Decompression
Status: UNKNOWN
Conditions: Lumbar Disc Herniation|Radiculopathy|Percutaneous Disc Decompression|3D Printing Guide Plate|Radicular Pain|Low Back Pain|Discogenic Pain
Interventions: OTHER: 3D printing guide plate|OTHER: Conventional guidance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Compare Combined Sphincterotomy and Balloon Dilation (ESBD) Versus Standard Sphincterotomy (ES) in Removing Biliary Stones
Status: COMPLETED
Conditions: Common Bile Duct Stone
Interventions: PROCEDURE: endoscopic balloon dilatation|PROCEDURE: Standard sphincterotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Thoracentesis to Alleviate Cardiac Pleural Effusion
Status: RECRUITING
Conditions: Heart Failure|Pleural Effusion
Interventions: PROCEDURE: Thoracentesis|DRUG: Standard-of-care medical treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nivolumab With Chemotherapy in Pleural Mesothelioma After Surgery
Status: ACTIVE_NOT_RECRUITING
Conditions: Pleural Mesothelioma Malignant
Interventions: DRUG: Carboplatin AUC 5|DRUG: Cisplatin 75 mg/m2|DRUG: Pemetrexed 500 mg/m2|BIOLOGICAL: Nivolumab Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study in Healthy Men to Test How BI 474121 is Tolerated
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Placebo|DRUG: BI 474121
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Develop and Test the 'Multi-Faced Continuous Exercise Program' in Operable Head and Neck Cancer Patients
Status: UNKNOWN
Conditions: Head and Neck Squamous Cell Carcinoma
Interventions: BEHAVIORAL: Exercise intervention program
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Impact of Vitamin C on Postoperative Acute Kidney Injury in Risk Patients Undergoing Valvular Heart Surgery
Status: UNKNOWN
Conditions: Acute Kidney Injury
Interventions: DRUG: Vitamin C|DRUG: Control (Normal saline)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Effect of Itraconazole and Rifampicin on the Pharmacokinetics of SY-5007 in Healthy Subjects
Status: NOT_YET_RECRUITING
Conditions: Healthy Subjects
Interventions: DRUG: SY-5007|DRUG: Itraconazole|DRUG: SY-5007|DRUG: Rifampin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Pharmacodynamic Effects of Single Oral Doses of PF-06648671 on β-Amyloid (Aβ) Concentrations in Cerebrospinal Fluid (CSF)
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: PF-06648671|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Planned Donor Lymphocyte Infusion (DLI) After Allogeneic Stem Cell Transplantation (SCT)
Status: TERMINATED
Conditions: Leukemia|Lymphoma|Myeloma|Myeloproliferative Diseases
Interventions: DRUG: Fludarabine|DRUG: Melphalan|DRUG: Alemtuzumab|PROCEDURE: Stem Cell Infusion|DRUG: Tacrolimus|DRUG: Methotrexate|DRUG: G-CSF|PROCEDURE: Low Dose Donor T-Cells|PROCEDURE: High Dose Donor T-Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Double-Blind,Double-Dummy,Efficacy/Safety,LCP-Tacro™ Vs Prograf®,Prevention Rejection,De Novo Adult Kidney Tx
Status: COMPLETED
Conditions: Renal Failure
Interventions: DRUG: Prograf (tacrolimus)|DRUG: LCP-Tacro
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Cemented vs Cementless Persona Keel RCT
Status: RECRUITING
Conditions: Knee Pain Chronic|Rheumatoid Arthritis|Osteoarthritis|Traumatic Arthritis|Polyarthritis|Avascular Necrosis|Varus Deformity|Valgus Deformity|Flexion Deformity of Knee
Interventions: DEVICE: Cementless Persona Knee System|DEVICE: Cemented Persona Knee System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Effect of a Probiotic Mixture in Obese Patients With Irritable Bowel Syndrome
Status: RECRUITING
Conditions: IBS - Irritable Bowel Syndrome|Obesity
Interventions: DIETARY_SUPPLEMENT: Probiotic mixture (OMNi-BiOTiC STRESS)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comprehensive Pain Programme to Determine Mechanism of Transition of Acute to Chronic Postsurgical Pain
Status: COMPLETED
Conditions: Chronic Pain|Anaesthesia|Genetics Predisposition
Interventions: OTHER: pain testing
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of RO7234292 (ISIS 443139) in Huntington's Disease Patients Who Participated in Prior Investigational Studies of RO7234292 (ISIS 443139)
Status: COMPLETED
Conditions: Huntington's Disease
Interventions: DRUG: RO7234292 (RG6042)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Late Fetal Loss in Poitou-Charentes. GYNE-COVID
Status: COMPLETED
Conditions: Identification of the Mother or Fetus Contamination by SARS Cov-2|Research the Presence of Viruses at Different Sites of the Mother and the Fetus or Father|The Survey Builds on a Network Work Already Organized Around the CPDPN of Poitou-Charentes|Analysis Laboratories of the Poitiers CHU
Interventions: DIAGNOSTIC_TEST: Identification by PCR of the SARS-COV-2 virus in samples taken from the fetus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Implementation of a Behavioural Medicine Approach in Physical Therapy for Treatment of Chronic Pain
Status: UNKNOWN
Conditions: Chronic Pain|Musculoskeletal Pain
Interventions: BEHAVIORAL: Active implementation clinics|BEHAVIORAL: Passive implementation clinics
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BTE and Pulsed Waveforms for Cardioversion of Atrial Fibrillation - Escalation Strategy and Manual Pressure
Status: UNKNOWN
Conditions: Atrial Fibrillation
Interventions: PROCEDURE: Cardioversion with a pulsed biphasic waveform|PROCEDURE: Cardioversion with a biphasic truncated exponential waveform
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sym004 vs Standard of Care in Subjects With Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: Sym004 (12 mg/kg)|DRUG: Sym004 (9/6 mg/kg)|OTHER: Best Supportive Care (BSC)|DRUG: Fluorouracil (5-FU)|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Biliopancreatic Diversion on Glucose Homeostasis
Status: COMPLETED
Conditions: Obesity, Morbid
Interventions: PROCEDURE: Roux-en-Y Gastric Bypass Surgery|PROCEDURE: Biliopancreatic Diversion Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Phase 2B Study of PTC124 (Ataluren) in Duchenne/Becker Muscular Dystrophy (DMD/BMD)
Status: COMPLETED
Conditions: Duchenne Muscular Dystrophy|Becker Muscular Dystrophy
Interventions: DRUG: Ataluren|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Efficacy of Rituximab in Combination With Low-dose Radiotherapy in Patients With Relapsed Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Non-Hodgkin's Lymphoma
Interventions: DRUG: Rituximab|PROCEDURE: Total nodal irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Implementing Tobacco Use Guidelines in Community Health Centers in Vietnam Public Health System
Status: COMPLETED
Conditions: Tobacco Use Cessation
Interventions: BEHAVIORAL: Technical Assistance, training and clinical reminders|BEHAVIORAL: TTC+Referral to Community Health Worker
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Quality of Recovery After Laparoscopic Cholecystectomy Comparing Opioid Free Analgesia Versus Opioid Free Anesthesia
Status: RECRUITING
Conditions: Quality of Recovery|Pain, Postoperative|Elective Laparoscopic Cholecystectomy
Interventions: DRUG: Opioid free analgesia|DRUG: Opioid based Anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: An Open-label, Phase II Study of AZD4635 in Patients With Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer|Metastatic Castration-Resistant Prostate Cancer (mCRPC)
Interventions: DRUG: AZD4635|DRUG: Oleclumab|DRUG: Durvalumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Self Administered Injections of Pegvaliase (>40mg/Day Dose) in Adults With PKU
Status: COMPLETED
Conditions: Phenylketonuria (PKU)
Interventions: DRUG: Pegvaliase
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cannabidiol for the Treatment of Pelvic Pain in Endometriosis (DREAMLAND)
Status: RECRUITING
Conditions: Endometriosis|Pelvic Pain
Interventions: DRUG: Cannabis Derivatives|DRUG: Placebo|DRUG: Hormonal Contraceptive Agents
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neurophysiological Mechanisms of Physical Activity Interventions in Unique Environments
Status: WITHDRAWN
Conditions: Environmental Exposure|Physical Activity
Interventions: BEHAVIORAL: Physical Activity
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Alternate Chemotherapy Regimens for the Clearance of W.Bancrofti Infection
Status: COMPLETED
Conditions: Filarial; Infestation
Interventions: DRUG: Diethylcarbamazine|DRUG: Albendazole|DRUG: Doxycycline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Newly Modified Technique for Levator Muscle Tucking in Blepharoptosis Surgery: An Egyptian Tertiary Center Study
Status: COMPLETED
Conditions: Mild Ptosis|Moderate Ptosis
Interventions: PROCEDURE: Mild _moderate Ptosis tucking
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Efficacy and Safety of Topical 1% Medroxyprogesterone in the Corneal Epithelium Healing After PRK
Status: COMPLETED
Conditions: Photorefractive Keratectomy
Interventions: DRUG: prepared drop of medroxy progestrone acetat 1%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of a Subunit Trivalent Influenza Vaccine, Northern Hemisphere Formulation 2013/2014, in Healthy Adults Aged 18 Years and Above
Status: COMPLETED
Conditions: Human Influenza
Interventions: BIOLOGICAL: TIV
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Prebiotic Fiber as a Modifier of Satiety Hormones and Body Weight in Overweight and Obese Adults
Status: COMPLETED
Conditions: Obesity
Interventions: DIETARY_SUPPLEMENT: Oligofructose|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Reducing Alcohol Exposed Pregnancy Risk: EARLY Randomized Controlled Trial
Status: COMPLETED
Conditions: Alcohol Exposed Pregnancy
Interventions: BEHAVIORAL: Motivational Interviewing plus feedback|BEHAVIORAL: Video|BEHAVIORAL: Informational Brochure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Vaccine Treatment in Combination With IL-2 and Treated Lymphocytes for Advanced Melanoma
Status: COMPLETED
Conditions: Melanoma
Interventions: DRUG: IL-2|DRUG: gp100:209-217|DRUG: OKT3|DRUG: rF-go 100P209|DRUG: Montanide ISA 51
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Pharmacokinetics and Pharmacodynamics of Dabigatran Etexilate in Patients With Stable Severe Renal Disease.
Status: COMPLETED
Conditions: Renal Insufficiency, Chronic
Interventions: DRUG: Dabigatran Etexilate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Determination of the Postprandial Responses to Two Cereal Foods Differing by Their SDS Content Consumed Alone.
Status: COMPLETED
Conditions: Metabolic Disorder; Carbohydrate, Absorption, Intestine
Interventions: OTHER: Sandwich biscuit high in SDS|OTHER: Co-extruded cereal low in SDS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study Of PHENYTOIN Suspension Made By Pfizer, Versus EPAMIN® Made By McNeil LA LLC In Healthy Volunteers Under Fasting Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Phenytoin|DRUG: Epamin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Long-term Outcomes of Ablation, Liver Resection, and Liver Transplant as First-line Treatment for Solitary HCC of 3 cm or Less
Status: COMPLETED
Conditions: Hepatocellular Carcinoma
Interventions: PROCEDURE: Radiofrequency ablation|PROCEDURE: Liver resection|PROCEDURE: Liver transplantation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluating Clinical Outcomes of Targeted Radiofrequency Ablation and Kyphoplasty (Also Known as Vertebral Augmentation) to Treat Painful Metastatic Vertebral Body Tumors
Status: TERMINATED
Conditions: Metastatic Lesions in Vertebral Bodies
Interventions: DEVICE: STAR™ Tumor Ablation System and StabiliT® Vertebral Augmentation System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Novel Measurement and Fitting Methods to Determine Their Reliability, Validity and Application - Sonova2018_34
Status: COMPLETED
Conditions: Hearing Loss
Interventions: DEVICE: Hearing aid: Phonak Audéo B90-Direct
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Investigating the Sensory Effects of Selenium-enriched Parsnips.
Status: UNKNOWN
Conditions: Food Sensory Perception|Selenium Status
Interventions: DIETARY_SUPPLEMENT: selenium enriched parsnips|DIETARY_SUPPLEMENT: Conventional parsnips
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Hypersensitivity to Opening of ATP-Sensitive Potassium Channels in Post-Traumatic Headache
Status: COMPLETED
Conditions: Post-Traumatic Headache
Interventions: DRUG: Levcromakalim|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety and Pharmacokinetic Study of Anthrax Immune Globulin Derived From Human Serum
Status: COMPLETED
Conditions: Symptoms of Inhalational Anthrax
Interventions: BIOLOGICAL: NP-015
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Double-Blind Placebo-Controlled Group Comparative Study To Evaluate the Safety and Effectiveness of Aerosol Pentamidine in the Prophylaxis of Pneumocystis Carinii Pneumonia in Patients With AIDS Post First Episode PCP
Status: COMPLETED
Conditions: Pneumonia, Pneumocystis Carinii|HIV Infections
Interventions: DRUG: Pentamidine isethionate
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Effect of Bisphosphonate on Bone Loss in Postmenopausal Women With Breast Cancer Initiating Aromatase Inhibitor Therapy
Status: COMPLETED
Conditions: Bone Loss|Osteoporosis|Breast Cancer
Interventions: DRUG: risedronate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Irinotecan-Eluting Beads in Treating Patients With Refractory Metastatic Colon or Rectal Cancer That Has Spread to the Liver
Status: TERMINATED
Conditions: Liver Metastases|Mucinous Adenocarcinoma of the Colon|Mucinous Adenocarcinoma of the Rectum|Recurrent Colon Cancer|Recurrent Rectal Cancer|Signet Ring Adenocarcinoma of the Colon|Signet Ring Adenocarcinoma of the Rectum|Stage IVA Colon Cancer|Stage IVA Rectal Cancer|Stage IVB Colon Cancer|Stage IVB Rectal Cancer
Interventions: COMBINATION_PRODUCT: irinotecan-eluting beads|PROCEDURE: hepatic artery embolization
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Topical Analgesic Versus Saline Mouth Rinses in Post Extraction Healing
Status: COMPLETED
Conditions: Tooth Extraction Site Healing
Interventions: DRUG: Aspirin Powder|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CCB Safety Study in Treatment of Hypertension of ADPKD
Status: UNKNOWN
Conditions: Kidney, Polycystic, Autosomal Dominant
Interventions: DRUG: Candesartan|DRUG: Candesartan and Cilnidipine|DRUG: Candesartan plus non-CCB agents
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of a Self-Adhering Flowable Composite in Class I Cavities
Status: COMPLETED
Conditions: Tooth Diseases
Interventions: DEVICE: Vertise Flow|DEVICE: LuxaFlow|DEVICE: Teco Adhesive
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: RCT of Paclitaxel DEB Compared to Standard PTA in Dialysis Fistula
Status: COMPLETED
Conditions: Complication of Hemodialysis|Vascular Access Complication
Interventions: DEVICE: DEB, drug eluting balloon|DEVICE: standard PTA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mézières Therapy in the UCAM's Athletes With Low Back Pain
Status: COMPLETED
Conditions: Low Back Pain|Postural; Strain
Interventions: OTHER: Mézières Therapy for Low back pain
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Novel Prebiotic Fiber for Targeted Dietary Management of Irritable Bowel Syndrome (Nutrabiotix Phase II)
Status: TERMINATED
Conditions: Constipation-predominant IBS (IBS-C)
Interventions: DIETARY_SUPPLEMENT: NTX-1|DRUG: psyllium (15 g)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Implant Surface Decontamination With 2 % Chlorhexidine in Peri-implantitis Treatment
Status: COMPLETED
Conditions: Periodontal Diseases|Peri-implantitis
Interventions: PROCEDURE: 2% chlorhexidine|PROCEDURE: 0.12% chlorhexidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Extracorporeal Shock Wave Lithotriptor Indicated for Fragmenting Urinary Stones in the Kidney
Status: UNKNOWN
Conditions: Kidney Stones
Interventions: DEVICE: LithoSpace Extracorporeal Shockwave Lithotripter
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Serum Tumor Endothelial Marker1 as a Potential Biomarker for Colorectal Cancer Diagnosis and Cancer Progression
Status: NOT_YET_RECRUITING
Conditions: Colorectal Cancer
Interventions: DIAGNOSTIC_TEST: Tumor Endothelial Marker 1 ( TEM1 ) by ELISA kits
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase 1 Study to Evaluate the Safety and Pharmacokinetics of Entecavir Extended Release (XR) in Healthy Subjects
Status: COMPLETED
Conditions: HBV
Interventions: DRUG: Entecavir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Kirschner Wires Fixation Versus Cannulated Screws Internal Fixation for Displaced Lateral Condyle Humeral Fracture in Children
Status: UNKNOWN
Conditions: Lateral Condyle Humerus Fracture in Children
Interventions: PROCEDURE: open reduction|PROCEDURE: Closed reduction|OTHER: Conservative management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Evaluate the Use of Liposuction and Cell Separation Devices for Autologous Fat (Adipose) Derived Cells to Treat the Symptoms of Erectile Dysfunction
Status: UNKNOWN
Conditions: Erectile Dysfunction
Interventions: DEVICE: Tissue Genesis Cell Isolation System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cardiovascular Events Among Adults Patients With Relapsed or Refractory Aggressive B-Cell Lymphoma Treated With Standard of Care Chimeric Antigen Receptor T Cell Therapy
Status: RECRUITING
Conditions: Recurrent Aggressive B-Cell Non-Hodgkin Lymphoma|Recurrent Diffuse Large B-Cell Lymphoma|Recurrent High Grade B-Cell Lymphoma|Recurrent Primary Mediastinal (Thymic) Large B-Cell Lymphoma|Recurrent Transformed Follicular Lymphoma to Diffuse Large B-Cell Lymphoma|Refractory Aggressive B-Cell Non-Hodgkin Lymphoma|Refractory Diffuse Large B-Cell Lymphoma|Refractory High Grade B-Cell Lymphoma|Refractory Primary Mediastinal (Thymic) Large B-Cell Lymphoma|Refractory Transformed Follicular Lymphoma to Diffuse Large B-Cell Lymphoma
Interventions: OTHER: Electronic Health Record Review
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Genetic Drug Study of Mycophenolic Acid (CellCept) in Pediatric Kidney Transplant Patients
Status: TERMINATED
Conditions: Kidney Transplant
Interventions: DRUG: Mycophenolate Mofetil (CellCept)|BEHAVIORAL: Dietary Monitoring|BEHAVIORAL: Drug Diary|PROCEDURE: Blood Sampling
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Interest of Continuous Non-Steroidal Anti-Inflammatory Drug Treatment in Ankylosing Spondylitis Patients Treated by Anti-TNF Therapy in the Prevention of Radiographic Outcomes
Status: COMPLETED
Conditions: Ankylosing Spondylitis
Interventions: DRUG: NSAIDs|DRUG: NSAIDs|DRUG: anti-TNF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: FFP Versus PCC in Intracranial Hemorrhage
Status: WITHDRAWN
Conditions: Intracranial Hemorrhage, Traumatic|Intracranial Hemorrhage, Spontaneous
Interventions: DRUG: Four Factor Prothrombin Complex Concentrate|BIOLOGICAL: Fresh Frozen Plasma
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pre-meal High-performance Inulin Supplementation in Healthy Non-diabetic Subjects
Status: COMPLETED
Conditions: Diet, Healthy
Interventions: DIETARY_SUPPLEMENT: No supplementation|DIETARY_SUPPLEMENT: High Performance (HP) Inulin|DIETARY_SUPPLEMENT: Isomalto-oligosaccharide (IMO)|DIETARY_SUPPLEMENT: Combination HP-Inulin and IMO|DIETARY_SUPPLEMENT: Dextrose solution|DIETARY_SUPPLEMENT: Glucose solution
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment by the CANS Score Versus Anthropometry and Impact on Early Neonatal Morbidities
Status: UNKNOWN
Conditions: Fetal Malnutrition
Interventions: DIAGNOSTIC_TEST: Clinical assessment of nutritional status (CANS) score|DIAGNOSTIC_TEST: Anthropometric indices|DIAGNOSTIC_TEST: Proportionality indices
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Epi-On Corneal Crosslinking for Keratoconus
Status: COMPLETED
Conditions: Keratoconus|Keratoconus, Unstable
Interventions: DRUG: Riboflavin 5'-Phosphate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prehabilitation in Liver Surgery
Status: COMPLETED
Conditions: Colorectal Cancer|Colorectal Liver Metastasis|Liver Surgery|Exercise Intervention
Interventions: BEHAVIORAL: Exercise Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Gastrocinemius Function Massage on Lower Extemity Spasticity
Status: ACTIVE_NOT_RECRUITING
Conditions: Stroke|Stroke Ischemic
Interventions: OTHER: Gastrocinemius Function Massage|OTHER: Sham application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Phase 1b Trial of Dinaciclib With Pembrolizumab for Advanced Breast Cancer
Status: COMPLETED
Conditions: Advanced or Metastatic Breast Cancer|Triple Negative Breast Cancer
Interventions: DRUG: Dinaciclib|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess Safety, Tolerability, and Immunogenicity of Three Heterologus 2-dose Regimens of the Candidate Prophylactic Vaccines for Ebola in Healthy Adults
Status: COMPLETED
Conditions: Ebola Viral Disease
Interventions: BIOLOGICAL: MVA-BN-Filo|BIOLOGICAL: Ad26.ZEBOV|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Improving HbA1c Levels Through Behavioural Change of Diabetes Self-management Assisted by the LovedBy Mobile Application for Young Adults and Adolescents With Type 1 Diabetes
Status: RECRUITING
Conditions: Diabetes Mellitus, Type 1
Interventions: DEVICE: LovedBy App
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effects of a Comprehensive Sexual Rehabilitation Programme in Heart Patients
Status: COMPLETED
Conditions: Ischaemic Heart Disease|Cardiac Arrhythmia|Sexual Dysfunction
Interventions: OTHER: sexual rehabilitation|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Efficacy of Suvorexant in the Treatment of Insomnia in Midlife Women With Pre-Diabetes
Status: RECRUITING
Conditions: Insomnia|Diabetes|Menopause
Interventions: DRUG: Suvorexant|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Guanfacine for the Treatment of Spatial Neglect and Impaired Vigilance
Status: COMPLETED
Conditions: Stroke|Hemispatial Neglect
Interventions: DRUG: Guanfacine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Troponin POCT in the Diagnosis of an Acute Myocardial Infarction
Status: COMPLETED
Conditions: Acute Myocardial Infarction|Troponin
Interventions: DIAGNOSTIC_TEST: Blood analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation of Atracurium-vecuronium Combination in Laparosocpic Surgery
Status: UNKNOWN
Conditions: Patients Undergoing Laparoscopic Surgery
Interventions: DRUG: Vecuronium|DRUG: Atracurium|DRUG: Vecuronium + Atracurium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Single Dose Study to Evaluate the Safety, and Efficacy of S-1226 (8%) in Subjects With Mild Atopic Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: S1226(8%)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Stochastic Modulated Vibrations on Autonomic Nervous System of Breast Cancer Patients During Radiotherapy
Status: UNKNOWN
Conditions: Autonomic Nervous System Imbalance|Psychological Distress|Cancer-related Pain|Breast Cancer Lymphedema|Quality of Life
Interventions: DEVICE: Andullation|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Elimination of Peritoneal Tumor Cells With Extensive Peritoneal Lavage During Surgery in Patients With Gastric Cancer
Status: TERMINATED
Conditions: Adenocarcinoma|Stomach Neoplasms
Interventions: PROCEDURE: Extensive Intraperitoneal Lavage (EIPL)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of a Dopamine Agonist on Pharmacodynamics of Levodopa in Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DRUG: pramipexole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Myocardial Protection in Patients With Post-acute Inflammatory Cardiac Involvement Due to COVID-19
Status: RECRUITING
Conditions: COVID-19 Associated Cardiac Involvement|Remodeling, Left Ventricle|Remodeling, Vascular|Left Ventricular Dysfunction|Exercise Intolerance|Vascular Inflammation|Microvascular Angina
Interventions: DRUG: Prednisolone|DRUG: Losartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bone Marrow Derived Adult Stem Cells for Acute Anterior Myocardial Infarction
Status: COMPLETED
Conditions: Acute Myocardial Infarction
Interventions: OTHER: Bone marrow derived progenitor cells or placebo infusion|OTHER: Placebo infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Mobile App Home Monitoring on the Number of In-Person Visits Following Ambulatory Surgery
Status: COMPLETED
Conditions: Use of Mobile App Home Monitoring After Ambulatory Surgery
Interventions: DEVICE: Mobile app follow-up care|OTHER: Conventional, in-person follow-up care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Single Shot Lumbar Erector Spinae Plane (ESP) Block in Total Hip Replacement (THR)
Status: COMPLETED
Conditions: Total Hip Replacement|Analgesia
Interventions: PROCEDURE: single shot lumbar Erector Spinae Plane block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Influence of Vascular Burden, Amyloid Plaque and Tau Protein in Patients With Vascular Cognitive Impairment and Dementia With Tauopathy
Status: RECRUITING
Conditions: Vascular Cognitive Impairment, Alzheimer's Disease, Fronto-temporal Dementia
Interventions: DRUG: PMPBB3|DRUG: AV45
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Enteral Nutrition Support for Critically Ill Patients
Status: TERMINATED
Conditions: Respiratory Distress Syndrome,Adult|Acute Lung Injury
Interventions: OTHER: Enteral nutrition with fatty acids|OTHER: Standard Enteral Nutrition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adjustable Gravitational vs. Adjustable Differential Pressure Valves in iNPH
Status: UNKNOWN
Conditions: Normal Pressure Hydrocephalus
Interventions: DEVICE: MIETHKE M.blue®|DEVICE: MIETHKE proGAV 2.0® (with SA 2.0®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of Vemurafenib (RO5185426) in Participants With Metastatic or Unresectable Papillary Thyroid Cancer Positive for the BRAF V600 Mutation
Status: COMPLETED
Conditions: Neoplasms
Interventions: DRUG: Vemurafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT