pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Pilot Study of CyclaPlex Implant, an Enhanced Suture and Button Implant Device in Hallux Valgus Deformity
Status: UNKNOWN
Conditions: Hallux Valgus
Interventions: DEVICE: Cyclaplex bone anchor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Web-based Support for People With Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: BEHAVIORAL: Interactive web-based materials|BEHAVIORAL: Static web-based materials
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Transdermal Patch CVD 1000: The Effect of Heat on Nicotine Release From Nicotine Patches in Adult Smokers
Status: COMPLETED
Conditions: Smoking
Interventions: DRUG: Nicoderm patch first, then Aveva patch
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Observational Study for the Evaluation of Incidence of Familial AML/MDSs in Patients With Myeloid Neoplasms
Status: RECRUITING
Conditions: Acute Myeloid Leukemia|Familial Acute Myeloid Leukemia|Myelodysplastic Syndromes
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Inhibition of NO-Synthesis on Renal Hemodynamics and Sodium Excretion in Patients With Essential Hypertension and Healthy Controls
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Ng-monomethyl-L-arginine (drug)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE|Primary Purpose:
Clinical trial: A Four Part Study to Investigate Relative Bioavailability, Safety and Tolerability of up to 5 Oral Formulation of GSK2251052 in Order to Identify a Formulation for Further Evaluation in a Future Later Phase Study
Status: TERMINATED
Conditions: Community-acquired Infection
Interventions: DRUG: GSK2251052
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Improve Oxygenation and Capnographic Detection During Sedative EGD
Status: COMPLETED
Conditions: Upper Airway Obstruction|Apnea, Obstructive
Interventions: DEVICE: Olympus standard bite block|DEVICE: YX mandibular advancement bite block|DEVICE: Optiflow High flow nasal cannula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pilot Study of the Coronary Spur Stent for In-stent Restenosis (DEEPER CORONARY)
Status: RECRUITING
Conditions: In-stent Restenosis
Interventions: DEVICE: Drug-eluting Coronary Spur Stent System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gene Therapy for RPGR Gene Mutation-associated X-linked Retinitis Pigmentosa
Status: RECRUITING
Conditions: X-Linked Retinitis Pigmentosa (XLRP)
Interventions: GENETIC: FT-002
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Xylitol for Caries Prevention in Inner-City Children
Status: COMPLETED
Conditions: Dental Caries
Interventions: DIETARY_SUPPLEMENT: Xylitol gummy bears|DIETARY_SUPPLEMENT: Sugar free fiber gummy bears|BEHAVIORAL: Oral health education|DEVICE: Fluoride varnish|DEVICE: Dental sealant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Cognitive Remediation Program for Hospitalized in the Long Term Patients With Deficit Schizophrenia
Status: WITHDRAWN
Conditions: Schizophrenia
Interventions: BEHAVIORAL: IPT+|BEHAVIORAL: Treatment as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Pharmacokinetic Study of Three Different Particle Sizes of PH-797804
Status: WITHDRAWN
Conditions: Healthy
Interventions: DRUG: PH-797804|DRUG: PH-797804|DRUG: PH-797804|DRUG: PH-797804|DRUG: PH-797804|DRUG: PH-797804
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Fenestrated AAA Endovascular Graft Post-Approval Study
Status: COMPLETED
Conditions: Abdominal Aortic Aneurysm (AAA)|Aorto-iliac Aneurysm|Juxtarenal Aneurysm
Interventions: DEVICE: Zenith® Fenestrated AAA Endovascular Graft
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Training on Endothelial Function, Progression of Disease,Inflammation, Heart Rate Variability and Mental Health After Percutaneous Coronary Intervention
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: BEHAVIORAL: exercise training
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Outcomes of Renal Function in Hepatorenal Syndrome (HRS) Determined By Comparison of Target Mean Arterial Pressure (MAP) of 65 - 70 Mmhg Versus ≥ 85 Mmhg
Status: COMPLETED
Conditions: Hepatorenal Syndrome
Interventions: DRUG: Norepinephrine (Levophed)|DRUG: Norepinephrine (Levophed)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transcranial Magnetic Stimulation (TMS) Effects on Pain Perception
Status: WITHDRAWN
Conditions: Pain|Trigeminal Neuralgia|Neuropathic Pain
Interventions: DEVICE: laboratory pain assessment|PROCEDURE: transcranial magnetic stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Find the Best Dose of BI 836880 Alone and in Combination With BI 754091 in Japanese Patients With Different Types of Advanced Cancer
Status: COMPLETED
Conditions: Neoplasms
Interventions: DRUG: BI 836880|DRUG: BI 754091
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Bioequivalence Study Comparing Cilnidipine/Valsartan Combination With Coadministration of Cilnidipine and Valsartan
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Cilnidipine/Valsartan|DRUG: Cilnidipine+Valsartan|DRUG: Cilnidipine/Valsartan|DRUG: Cilnidipine+Valsartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: FSME IMMUN NEW Follow-up to Study 199 in Children Aged 1 to 6 Years
Status: COMPLETED
Conditions: Encephalitis, Tick-borne
Interventions: BIOLOGICAL: Tick-Borne Encephalitis (TBE) Vaccine (Inactivated)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose:
Clinical trial: Evaluation of Liver Grafts With FibroScan® Before Organ Retrieval in Patients With Brain Death
Status: COMPLETED
Conditions: Tissue and Organ Harvesting|Liver Transplantation|Brain Death
Interventions: PROCEDURE: Fibroscan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Evaluate Corneal Endothelial Cell Density (ECD) in Subjects With Dry Eye Disease (DED) Administering Miebo® (Perfluorohexyloctane Ophthalmic Solution) for 12 Months.
Status: RECRUITING
Conditions: Dry Eye
Interventions: DRUG: Miebo|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: EncoreAnywhere Use in Motor Neurone Disease
Status: COMPLETED
Conditions: Motor Neuron Disease
Interventions: DEVICE: EncoreAnywhere with data available to review|DEVICE: EncoreAnywhere with no data available to review
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Effect of Dexmedetomidine on Stress Study of Pituitrin in Laparoscopic Hysteromyoma Surgery
Status: UNKNOWN
Conditions: Hysteromyoma
Interventions: DRUG: Dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Prevention of Postop Atrial Fibrillation Through Intraoperative Inducibility of Atrial Fibrillation and Amiodarone Treatment
Status: RECRUITING
Conditions: Postoperative Atrial Fibrillation
Interventions: DRUG: Amiodarone Injection|DEVICE: Intraoperative Rapid Atrial Pacing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Delineating Swallowing Impairment and Decline in ALS
Status: COMPLETED
Conditions: Amyotrophic Lateral Sclerosis
Interventions: PROCEDURE: Videofluoroscopic Swallowing Study (VFSS)|DEVICE: Voluntary Peak Cough Flow Testing|DEVICE: Iowa Oral Performance Instrument|DRUG: Capsaicin Challenge|DEVICE: Pulmonary Function Testing|OTHER: Eating Assessment Tool 10|OTHER: The Center for Neurologic Study Bulbar Function Scale
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Simeprevir in Combination With Sofosbuvir in Treatment-Naïve or -Experienced Adults With Chronic Genotype 4 Hepatitis C Virus Infection
Status: COMPLETED
Conditions: Chronic Hepatitis C
Interventions: DRUG: Simeprevir|DRUG: Sofosbuvir
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Theory Based Intervention Program to Support Physical Activity for Individuals With Multiple Sclerosis: a Case Series
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: BEHAVIORAL: Motivational Interviewing|DEVICE: Wristband physical activity monitor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ispinesib in Treating Patients With Metastatic or Unresectable Kidney Cancer
Status: COMPLETED
Conditions: Recurrent Renal Cell Cancer|Stage III Renal Cell Cancer|Stage IV Renal Cell Cancer
Interventions: DRUG: ispinesib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase IIA Study of MK0457 in Patients With Cancer of the Lung (0457-006)
Status: TERMINATED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: MK0457
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Subclinical Hypothyroidism and Mind in the Elderly
Status: COMPLETED
Conditions: Subclinical Hypothyroidism
Interventions: DRUG: levothyroxine sodium|DRUG: excipient without levothyroxine (placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ultrasound Assessment of Volume in Patients on Continuous Dialysis
Status: COMPLETED
Conditions: Volume Overload|Kidney Failure|Respiratory Failure
Interventions: OTHER: Share ultrasound measurement of IVC collapsibility to Nephrology Attending|OTHER: Do not share ultrasound measurement of IVC collapsibility to Nephrology Attending
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of Ruxolitinib Phosphate Cream When Applied to Patients With Plaque Psoriasis
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: Ruxolitinib phosphate cream|DRUG: Dovonex® calcipotriene 0.005%|DRUG: Diprolene® AF betamethasone dipropionate 0.05% cream.|DRUG: Placebo cream|DRUG: Ruxolitinib phosphate cream|DRUG: Ruxolitinib phosphate cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1b Study of PTC596 in Children With Newly Diagnosed Diffuse Intrinsic Pontine Glioma and High Grade Glioma
Status: ACTIVE_NOT_RECRUITING
Conditions: High Grade Glioma|Diffuse Intrinsic Pontine Glioma
Interventions: DRUG: PTC596|RADIATION: Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Association Between Alpha 1 Acid Glycoprotein Level and Outcome Metastatic Cancer Treated With Docetaxel
Status: UNKNOWN
Conditions: Metastatic Lung Cancer|Metastatic Breast Cancer|Metastatic Gastric Cancer|Metastatic Prostate Cancer|Metastatic Bladder Cancer
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A New Paradigm for Vitamin D Sufficiency
Status: COMPLETED
Conditions: New Biomarkers for Measuring Vitamin D Level
Interventions: DIETARY_SUPPLEMENT: Vitamin D Supplementation|OTHER: Placebo|DIETARY_SUPPLEMENT: Calcium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study of Monalizumab and Cetuximab in Patients With Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck
Status: COMPLETED
Conditions: Head and Neck Neoplasms
Interventions: BIOLOGICAL: Monalizumab|BIOLOGICAL: Cetuximab|BIOLOGICAL: Anti-PD(L)1
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Safety and Tolerability of a Bowel Cleansing Preparation (BLI800) in Pediatric Subjects Undergoing Colonoscopy
Status: COMPLETED
Conditions: Colonoscopy
Interventions: DRUG: BLI800 - Dose 1|DRUG: BLI800 - Dose 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anti-CD19 Chimeric Antigen Receptor (CAR)-Transduced T Cell Therapy for Patients With B Cell Malignancies
Status: UNKNOWN
Conditions: Chronic Lymphocytic Leukemia|Acute Lymphocytic Leukemia|Lymphoma
Interventions: DRUG: Fludarabine|DRUG: Cyclophosphamide|BIOLOGICAL: Anti-CD19-CAR transduced T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Pemetrexed Plus Cisplatin in Patients With Malignant Pleural Mesothelioma
Status: COMPLETED
Conditions: Malignant Pleural Mesotherioma
Interventions: DRUG: Pemetrexed|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Maintenance Study of Certolizumab Pegol (CZP) in Crohn's Disease
Status: COMPLETED
Conditions: Crohn's Disease
Interventions: BIOLOGICAL: Certolizumab pegol (CZP)|BIOLOGICAL: Certolizumab pegol (CZP)|BIOLOGICAL: Certolizumab pegol (CZP)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phone or Email Reminder in Increasing Vaginal Dilator Use in Patients With Gynecologic Cancers Undergoing Brachytherapy
Status: COMPLETED
Conditions: Cervical Cancer|Endometrial Cancer|Radiation Toxicity|Vaginal Cancer
Interventions: OTHER: survey administration|OTHER: computer-assisted intervention|BEHAVIORAL: telephone-based intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Lamotrigine and Bupropion for Meniere's Disease
Status: RECRUITING
Conditions: Meniere Disease|Ménière's Vertigo|Vertigo, Intermittent|Vertigo, Aural
Interventions: DRUG: Lamotrigine and Bupropion|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Clinical Trial of Overminus Spectacle Therapy for Intermittent Exotropia
Status: COMPLETED
Conditions: Intermittent Exotropia
Interventions: DEVICE: Overminus treatment|DEVICE: Non-overminus treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neuropsychological and Oncological Outcomes in Grade 2 or 3 Glioma Patients Undergoing Postoperative Modern Radiotherapy
Status: RECRUITING
Conditions: Glioma of Brain
Interventions: RADIATION: postoperative adjuvant RT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pyridoxine in Preventing Hand-Foot Syndrome in Patients Who Are Receiving Liposomal Doxorubicin for Cancer
Status: COMPLETED
Conditions: Breast Cancer|Drug/Agent Toxicity by Tissue/Organ|Endometrial Cancer|Fallopian Tube Cancer|Ovarian Cancer|Peritoneal Cavity Cancer
Interventions: DIETARY_SUPPLEMENT: pyridoxine hydrochloride|DRUG: Placebo|DRUG: doxorubicin HCL liposome
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Single-Dose Study to Evaluate the PKs of Pretomanid in Participants With Renal Impairment Compared to Participants With Normal Renal Function
Status: RECRUITING
Conditions: Renal Impairment|Tuberculosis
Interventions: DRUG: PA-824
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Olaparib Maintenance Following Cabazitaxel-Carbo in Men With AVPC
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Cancer Aggressiveness|Prostate Carcinoma
Interventions: DRUG: Cabazitaxel|DRUG: Carboplatin|DRUG: Prednisone 5Mg|DRUG: Olaparib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Yoga Breath Training to Improve Cardiorespiratory Synchrony in Spinal Cord Injury
Status: NOT_YET_RECRUITING
Conditions: Spinal Cord Injuries
Interventions: BEHAVIORAL: Ujjayi Yogic Breathing
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pharmacokinetics and Safety of a New Micellar Glutathione Formulation
Status: COMPLETED
Conditions: Bioavailability|Safety
Interventions: DIETARY_SUPPLEMENT: Liposomal Glutathione|DIETARY_SUPPLEMENT: Standard Glutathione|DIETARY_SUPPLEMENT: New Micellar Glutathione (Lipomicel)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Flow Dysfunction of Hemodialysis Vascular Access
Status: RECRUITING
Conditions: Dialysis Access Malfunction|Hemodialysis Access Failure|Hemodialysis Fistula Thrombosis|Vascular Access Malfunction
Interventions: DIAGNOSTIC_TEST: Vascular access monitoring|DIAGNOSTIC_TEST: Vascular access blood flow measurement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Effect of Bone Marrow Aspirate Concentrate on Distracted Mandibular Bone Properties
Status: COMPLETED
Conditions: Hemifacial Microsomia|Distraction of Bone
Interventions: OTHER: Bone Marrow Aspirate Concentrate|OTHER: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence of the New Formulation of WAL 801 CL Dry Syrup Compared to the Conventional Formulation of WAL 801 CL Dry Syrup in Healthy Male Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: WAL 801 CL dry syrup new formulation|DRUG: WAL 801 CL dry syrup conventional formulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RBx11160 Phase II Dose Ranging Study RBx/MMV05-06
Status: COMPLETED
Conditions: Plasmodium Falciparum Malaria
Interventions: DRUG: Treatment with 3 dose groups of RBx11160 over 7 days
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: To Evaluate Safety and Efficacy of CGBIO Stent Compared to Biomatrix Flex Stent
Status: UNKNOWN
Conditions: Ischemic Heart Disease|Stable Coronary Artery Disease|Stable Angina|Unstable Angina|NSTEMI - Non-ST Segment Elevation MI
Interventions: DEVICE: CGBio stent|DEVICE: Biomatrix flex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Surgery Versus Non-surgical Treatment for Esophageal Squamous Cell Carcinoma in Patients Older Than 70 Years
Status: COMPLETED
Conditions: Esophageal Squamous Cell Carcinoma|Esophagectomy|Radiotherapy|Chemotherapy
Interventions: DIAGNOSTIC_TEST: Since the data were collected retrospectively, there were no interventions
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Cyclic Versus Continuous Sacral Neuromodulation for LUTS
Status: RECRUITING
Conditions: Overactive Bladder Syndrome
Interventions: DEVICE: Cyclic SNM|DEVICE: Continuous SNM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Encorafenib, Cetuximab, and Nivolumab in Treating Patients With Microsatellite Stable, BRAFV600E Mutated Unresectable or Metastatic Colorectal Cancer
Status: RECRUITING
Conditions: BRAF NP_004324.2:p.V600E|Metastatic Colon Adenocarcinoma|Metastatic Microsatellite Stable Colorectal Carcinoma|Metastatic Rectal Adenocarcinoma|Progressive Disease|Recurrent Colorectal Carcinoma|Stage III Colorectal Cancer AJCC v8|Stage IIIA Colorectal Cancer AJCC v8|Stage IIIB Colorectal Cancer AJCC v8|Stage IIIC Colorectal Cancer AJCC v8|Stage IV Colorectal Cancer AJCC v8|Stage IVA Colorectal Cancer AJCC v8|Stage IVB Colorectal Cancer AJCC v8|Stage IVC Colorectal Cancer AJCC v8|Unresectable Colon Adenocarcinoma|Unresectable Rectal Adenocarcinoma
Interventions: BIOLOGICAL: Cetuximab|DRUG: Encorafenib|BIOLOGICAL: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Intravenous (I.V.) Iclaprim Versus Linezolid in Complicated Skin and Skin Structure Infections [cSSSI] (ASSIST-2)
Status: COMPLETED
Conditions: Skin Diseases, Bacterial
Interventions: DRUG: Intravenous iclaprim|DRUG: Intravenous linezolid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Eccentric Contraction-based Resistance Exercise for Chronic Stroke Patients
Status: UNKNOWN
Conditions: Stroke
Interventions: OTHER: usual care and exercise education|OTHER: Eccentric exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Progesterone for Cannabis Withdrawal
Status: COMPLETED
Conditions: Cannabis Use Disorder|Cannabis Withdrawal
Interventions: DRUG: Progesterone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison and Evaluation of USSQ, OABSS, and the Drainage/Anti-reflux Effect Between Three Kinds of Ureteral D-J Stents in Patients Who Underwent URL
Status: UNKNOWN
Conditions: Urolithiasis|Overactive Bladder Syndrome
Interventions: DEVICE: Placement of ureteral D-J stent after ureteroscopic holmium laser lithotripsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prognostic Impact of the Evolution of PAH 3 Months After TAVI (HTP-TAVI)
Status: TERMINATED
Conditions: Aortic Valve Stenosis|Pulmonary Hypertension
Interventions: PROCEDURE: Right Heart Catheterization
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Auricular Acupuncture in Patients With Multiple Myeloma
Status: RECRUITING
Conditions: Multiple Myeloma|Fatigue|Pain|Depression
Interventions: OTHER: Auricular Acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fecal Microbiota Transplantation and Newly Diagnosed Ulcerative Colitis (UC)
Status: RECRUITING
Conditions: Ulcerative Colitis
Interventions: OTHER: Fecal microbiota transplantation|OTHER: Colored water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacological Intervention for Symptomatic Mild Sleep Disordered Breathing
Status: COMPLETED
Conditions: Sleep Disordered Breathing
Interventions: DRUG: AD036|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of a Live-attenuated Universal Flu Vaccine Followed by an Inactivated Universal Flu Vaccine
Status: COMPLETED
Conditions: Influenza|Vaccine
Interventions: BIOLOGICAL: cH8/1N1 LAIV|BIOLOGICAL: AS03-adjuvanted cH5/1N1 IIV|BIOLOGICAL: cH5/1N1 IIV|BIOLOGICAL: AS03-adjuvanted cH8/1N1 IIV|BIOLOGICAL: Normal saline|BIOLOGICAL: Phosphate buffered saline (PBS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Derivation of Human Induced Pluripotent Stem (iPS) Cells to Heritable Cardiac Arrhythmias
Status: ENROLLING_BY_INVITATION
Conditions: Inherited Cardiac Arrythmias|Long QT Syndrome (LQTS)|Brugada Syndrome (BrS)|Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT)|Early Repolarization Syndrome (ERS)|Arrhythmogenic Cardiomyopathy (AC, ARVD/C)|Hypertrophic Cardiomyopathy (HCM)|Dilated Cardiomyopathy (DCM)|Muscular Dystrophies (Duchenne, Becker, Myotonic Dystrophy)|Normal Control Subjects
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of Sound Therapy in a Population of Women With Fibromyalgia Aged Between 30 and 60 Years
Status: COMPLETED
Conditions: Fibromyalgia
Interventions: OTHER: Sound therapy associated with relaxation|OTHER: Relaxation alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Electroencephalographic Changes Under General Anesthesia in Patients With Gynecologic Cancers With and Without History of Chemotherapy
Status: COMPLETED
Conditions: Malignant Female Reproductive System Neoplasm
Interventions: PROCEDURE: Biospecimen Collection|BEHAVIORAL: BrainCheck Cognitive Assessment|PROCEDURE: Cognitive Assessment|PROCEDURE: Electroencephalography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: One-Day Dispensing Clinical Evaluation of SofLens Daily Disposable Lenses Compared to a Marketed 1 Day Contact Lens
Status: COMPLETED
Conditions: Myopia
Interventions: DEVICE: SofLens Daily Disposable|DEVICE: Marketed 1 Day Contact Lens
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: BMS-986205 and Nivolumab as First or Second Line Therapy in Treating Patients With Liver Cancer
Status: TERMINATED
Conditions: Metastatic Hepatocellular Carcinoma|Stage III Hepatocellular Carcinoma AJCC v8|Stage IIIA Hepatocellular Carcinoma AJCC v8|Stage IIIB Hepatocellular Carcinoma AJCC v8|Stage IV Hepatocellular Carcinoma AJCC v8|Stage IVA Hepatocellular Carcinoma AJCC v8|Stage IVB Hepatocellular Carcinoma AJCC v8|Unresectable Hepatocellular Carcinoma
Interventions: DRUG: IDO1 Inhibitor BMS-986205|BIOLOGICAL: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Bioequivalence of Famotidine Chewable Tablets and Film-Coated Tablets (0208-144)
Status: COMPLETED
Conditions: Heartburn
Interventions: DRUG: Famotidine FCT|DRUG: Famotidine CT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improving Tissue Repair After Injury in the Muscle-tendon Interface Muscle Tissue Injury
Status: RECRUITING
Conditions: Muscle Injury
Interventions: PROCEDURE: Electrical stimulation|DRUG: Growth hormone (somatropin)|OTHER: Control (No electrical stimulation, nor growth hormone)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Bioinductive Patch for Full-Thickness Rotator Cuff Tears
Status: RECRUITING
Conditions: Rotator Cuff Tears|Rotator Cuff Tear Arthropathy
Interventions: PROCEDURE: arthroscopic rotator cuff repair|BIOLOGICAL: Bioinductive implant|DIAGNOSTIC_TEST: Ultrasound Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of Tazemetostat in Adult Participants With Soft Tissue Sarcoma
Status: COMPLETED
Conditions: Malignant Rhabdoid Tumors (MRT)|Rhabdoid Tumors of the Kidney (RTK)|Atypical Teratoid Rhabdoid Tumors (ATRT)|Selected Tumors With Rhabdoid Features|Synovial Sarcoma|INI1-negative Tumors|Malignant Rhabdoid Tumor of Ovary|Renal Medullary Carcinoma|Epithelioid Sarcoma|Poorly Differentiated Chordoma (or Other Chordoma With Sponsor Approval)|Any Solid Tumor With an EZH2 GOF Mutation
Interventions: DRUG: Tazemetostat
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Carvedilol for Pre-primary Prophylaxis of Esophageal Varices in Cirrhosis
Status: UNKNOWN
Conditions: Cirrhosis
Interventions: DRUG: carvedilol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Suprainguinal Fascia Iliaca Block Versus PENG Block for Hip Arthroplasty Analgesia
Status: COMPLETED
Conditions: Postoperative Complications|Postoperative Pain|Weakness, Muscle|Motor Activity
Interventions: PROCEDURE: Ultrasound-guided suprainguinal fascia iliaca nerve block|PROCEDURE: Ultrasound-guided pericapsular nerves group of the hip block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Low Sodium Dialysate and Ambulatory Blood Pressure Measurement Parameters
Status: UNKNOWN
Conditions: Chronic Renal Failure|Hypertension
Interventions: BIOLOGICAL: standart dialysis|BIOLOGICAL: low sodium dialysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: NBP in Women With Metastatic Breast Cancer to Prevent Nab-paclitaxel Induced Toxic Neuropathy
Status: WITHDRAWN
Conditions: Breast Cancer|Peripheral Neuropathy
Interventions: DRUG: Placebo|DRUG: NBP Softgel Capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Anthropometric Outcomes of a Mobile Health Intervention for Eating Behaviour and Lifestyle in Infancy
Status: NOT_YET_RECRUITING
Conditions: Childhood Obesity Prevention
Interventions: BEHAVIORAL: Feeding, Lifestyle, Activity Goals (FLAGs) Digital Health Application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of Monoclonal Antibody (mAb) in Patients With IPF
Status: COMPLETED
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: BIOLOGICAL: CHF10067 starting dose|BIOLOGICAL: CHF10067 intermediate dose|BIOLOGICAL: CHF10067 high dose|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Test the Safety and Effectiveness of Nivolumab Combined With Daratumumab in Patients With Pancreatic, Non-Small Cell Lung or Triple Negative Breast Cancers, That Have Advanced or Have Spread
Status: COMPLETED
Conditions: Advanced Cancer
Interventions: BIOLOGICAL: Nivolumab|BIOLOGICAL: Daratumumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study on the Safety of TAK-279 and Whether it Can Reduce Inflammation in the Bowel of Participants With Moderately to Severely Active Ulcerative Colitis
Status: RECRUITING
Conditions: Ulcerative Colitis
Interventions: DRUG: TAK-279|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Galunisertib and Capecitabine in Advanced Resistant TGF-beta Activated Colorectal Cancer
Status: WITHDRAWN
Conditions: Colorectal Cancer Metastatic
Interventions: DRUG: Galunisertib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Telehealth to In-person a Combined Metacognitive Training in Veterans With mTBI/PTSD
Status: RECRUITING
Conditions: Brain Injury|Cognition|PTSD|Intervention
Interventions: BEHAVIORAL: Goal Management Training plus Attention Training|BEHAVIORAL: Brain Health Workshop and National Geographic Movies
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: LEVosimendan to Improve Exercise Limitation in Patients With PH-HFpEF
Status: RECRUITING
Conditions: Pulmonary Hypertension
Interventions: DRUG: TNX-103|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial to Compare the Pharmacodynamic and Pharmacokinetic Properties of Biochaperone® Combo With Humalog® Mix25 and With Simultaneous Injections of Humalog® and Lantus® in Subjects With Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Biochaperone Combo|DRUG: Humalog Mix25|DRUG: Humalog|DRUG: Lantus|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: 3-AP and Fludarabine in Treating Patients With Myeloproliferative Disorders, Chronic Myelomonocytic Leukemia, or Accelerated Phase or Blastic Phase Chronic Myelogenous Leukemia
Status: COMPLETED
Conditions: Accelerated Phase Chronic Myelogenous Leukemia|Atypical Chronic Myeloid Leukemia, BCR-ABL1 Negative|Blastic Phase Chronic Myelogenous Leukemia|Chronic Eosinophilic Leukemia|Chronic Myelomonocytic Leukemia|Essential Thrombocythemia|Philadelphia Chromosome Negative Chronic Myelogenous Leukemia|Polycythemia Vera|Primary Myelofibrosis|Relapsing Chronic Myelogenous Leukemia
Interventions: DRUG: fludarabine phosphate|DRUG: triapine|PROCEDURE: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Induction of Gut Permeability by an Oral Vaccine
Status: ACTIVE_NOT_RECRUITING
Conditions: Intestinal Permeability|Inflammation|Vaccine|Typhoid Fever
Interventions: BIOLOGICAL: Vivotif Typhoid Oral Vaccine|DRUG: Aspirin (Positive Control)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of JMKX003948 Tablets in Patients With Renal Cell Carcinoma
Status: RECRUITING
Conditions: Renal Cell Carcinoma Metastatic
Interventions: DRUG: JMKX003948
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nutritional Intervention With Black Garlic
Status: UNKNOWN
Conditions: Hypercholesterolemia|Hypertension|Hyperlipidemias|Inflammation|Endothelial Dysfunction
Interventions: DIETARY_SUPPLEMENT: black garlic
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Impact of AGEs on Metabolism & Cognition
Status: UNKNOWN
Conditions: No Conditions
Interventions: OTHER: low fat, low AGE milkshake|OTHER: low fat, high AGE milkshake|OTHER: high fat, low AGE|OTHER: high fat, high AGE milkshake
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Telerehabilitation-Based Coaching Interventions (TeleSCoP) for Patients With Ischemic Stroke
Status: NOT_YET_RECRUITING
Conditions: Ischemic Stroke|Coaching
Interventions: BEHAVIORAL: Telerehabilitation Stroke Coaching of Program (TeleSCoP) group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Role of BCAA in Glucose Homeostasis
Status: NOT_YET_RECRUITING
Conditions: Type 2 Diabetes
Interventions: DRUG: 4.8 g/m^2/day NaPB|DRUG: 4.8 g/m^2/day placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: ICBT for Depression - A Factorial Investigation of Kinds of Therapist Support and Self-/Expert-selected Content
Status: COMPLETED
Conditions: Depressive Disorder, Major|Depressive Symptoms
Interventions: BEHAVIORAL: Internet-administered Cognitive behavioral therapy (ICBT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PROspective Multicenter Imaging Study for Evaluation of Chest Pain
Status: COMPLETED
Conditions: Chest Pain
Interventions: PROCEDURE: Coronary Angiography|PROCEDURE: Stress Echocardiogram|PROCEDURE: Nuclear Stress Test|PROCEDURE: Exercise Electrocardiogram
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study to Evaluate the Safety, Tolerability, Drug Levels and Drug Effects of BMS-986331 in Healthy Participants
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DRUG: BMS-986331|OTHER: Placebo, Matching BMS-986331
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Time-Restricted Eating and Muscle Hypertrophy
Status: COMPLETED
Conditions: Muscle Hypertrophy|Healthy and Well-Trained Men and Women
Interventions: OTHER: Time Restricted Eating|OTHER: Normal Feeding|OTHER: Resistance Training|DIETARY_SUPPLEMENT: Whey Protein
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Exogenous Ketones in Type 2 Diabetes
Status: COMPLETED
Conditions: Ketosis|Type 2 Diabetes
Interventions: DIETARY_SUPPLEMENT: Ketone monoester|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Clinical Effectiveness of Pre-operative Methadone in Single Level Lateral Transpsoas Interbody Fusions
Status: UNKNOWN
Conditions: Degenerative Disc Disease|Spondylolisthesis, Lumbar Region
Interventions: DRUG: Methadone Hydrochloride|DRUG: Oxycodone-Acetaminophen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Combination Therapies With Viagenpumatucel-L (HS-110) in Patients With Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer
Interventions: BIOLOGICAL: Viagenpumatucel-L|DRUG: Nivolumab|DRUG: Pembrolizumab|DRUG: Pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of AGN208397 in the Treatment of Macular Edema Associated With Retinal Vein Occlusion (RVO)
Status: COMPLETED
Conditions: Macular Edema|Retinal Vein Occlusion
Interventions: DRUG: AGN208397 intravitreal injection|DRUG: dexamethasone intravitreal implant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Chlorthalidone + Amiloride to Elderly Patients Treatment With Arterial Hypertension
Status: UNKNOWN
Conditions: Arterial Hypertension
Interventions: DRUG: Chlorthalidone 25 mg + amiloride hydrochloride 5 mg|DRUG: Higroton® Laboratório Novartis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Behavioral Weight Loss Treatment for Individuals With Food Addiction
Status: COMPLETED
Conditions: Food Addiction|Overweight and Obesity|Weight Loss
Interventions: BEHAVIORAL: Behavioral Weight Loss (BWL) counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Gene Modified Immune Cells in Patients With Advanced Melanoma
Status: COMPLETED
Conditions: Metastatic Melanoma
Interventions: BIOLOGICAL: F5 TCR transgenic cells and MART-1 peptide pulsed dendritic cells|DRUG: non-myeloablative conditioning chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigation of Pharmacokinetic Drug-drug Interaction of BI 409306 and Donepezil in Healthy Male and Female Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BI 409306|DRUG: Donepezil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Controlled Human Malaria Infection After Bites From Mosquitoes Infected With Two Novel P. Falciparum Strains
Status: COMPLETED
Conditions: Malaria
Interventions: OTHER: NF135 n=5|OTHER: NF135 n=2|OTHER: NF135 n=1|OTHER: NF166 n=5|OTHER: NF166 n=2|OTHER: NF166 n=1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Sanaria PfSPZ Challenge With Pyrimethamine or Chloroquine Chemoprophylaxis Vaccination (PfSPZ-CVac Approach): A Randomized Double Blind Placebo Controlled Phase I/II Trial to Determine Safety and Protective Efficacy Against Natural Plasmodium Falcipa...
Status: COMPLETED
Conditions: Malaria
Interventions: DRUG: Chloroquine Phosphate|BIOLOGICAL: PfSPZ Challenge|DRUG: Pyrimethamine|DRUG: Coartem|DRUG: ibuprofen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: A Novel Approach for Reducing Hyperoxaluria and Kidney Stone Risk.
Status: RECRUITING
Conditions: Hyperoxaluria
Interventions: DRUG: Tenapanor|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: BMS-247550 Plus Cisplatin in Treating Patients With Metastatic or Recurrent Head and Neck Cancer
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: DRUG: cisplatin|DRUG: ixabepilone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Antibiotic Irrigation to Decrease Wound Infections in Pediatric Perforated Appendicitis
Status: ACTIVE_NOT_RECRUITING
Conditions: Perforated Appendicitis
Interventions: DRUG: antibiotic rinse with suction|PROCEDURE: suction only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Family-based Health Education Program and Zinc Supplementation for Stunted Mother
Status: UNKNOWN
Conditions: Stunting|Maternal-Fetal Relations
Interventions: DIETARY_SUPPLEMENT: Zinc|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparative Study To Determine The Efficacy, Safety, And Tolerability Of Ceftolozane-Tazobactam
Status: COMPLETED
Conditions: Other Infectious Diseases
Interventions: DRUG: Cefepime|DRUG: Ceftolozane|OTHER: Laboratory Biomarker Analysis|DRUG: Meropenem|DRUG: Piperacillin-Tazobactam|DRUG: Tazobactam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT