pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Study of Prineo (Dermabond Protape) Versus Sutures in Breast Procedures
Status: COMPLETED
Conditions: Macromastia
Interventions: DEVICE: Dermabond Protape (Prineo)|DEVICE: Suture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SLeep and OPioid UsE in Patients Undergoing Total Knee Arthroplasty
Status: ACTIVE_NOT_RECRUITING
Conditions: Opioid Use|Pain, Postoperative|Sleep|Delirium
Interventions: DIETARY_SUPPLEMENT: Melatonin|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Contoura With Phorcides Compared to Wavefront Optimized LASIK
Status: RECRUITING
Conditions: Myopia|Astigmatism
Interventions: PROCEDURE: Contoura with Phorcides|DEVICE: WaveLight Wavefront Optimized
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Androgen Effect on Klinefelter Syndrome Motor Outcome
Status: COMPLETED
Conditions: Klinefelter Syndrome
Interventions: DRUG: androgen oxandrolone|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: ALADDIN Study - Phase III: Antigonadotropin-Leuprolide in Alzheimer's Disease Drug INvestigation (VP-AD-301)
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: VP4896
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Randomised Trial Investigating the Pharmacokinetic and Pharmacodynamic Properties of Faster-acting Insulin Aspart in Subjects With Type 1 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 1
Interventions: DRUG: Faster-acting insulin aspart|DRUG: insulin aspart
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Role of Type 2 Diabetes on Skeletal Muscle Atrophy and Recovery Following Bed Rest in Older Adults
Status: RECRUITING
Conditions: Type 2 Diabetes|Muscle Atrophy|Aging|Sedentary Behavior|Pre-diabetes
Interventions: BEHAVIORAL: Bed rest
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Inner Engineering Yoga Program on Short and Long Term Health Effects (ISHA-Impact): A Longitudinal Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Mediation|Mood|Stress|Habits|Nicotine|Alcohol Consumption|Pain Intensity|Sleep|Mindfulness|Emotions|Anxiety|Depression
Interventions: BEHAVIORAL: Inner Engineering Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Cytokine Induced Memory-like NK Cell Adoptive Therapy After Haploidentical Donor Hematopoietic Cell Transplantation
Status: RECRUITING
Conditions: Acute Myeloid Leukemia
Interventions: PROCEDURE: Graft cell infusion|DRUG: Tacrolimus|DRUG: Mycophenolate mofetil|DRUG: G-CSF|PROCEDURE: CIML NK cell infusion|DRUG: ALT-803|PROCEDURE: Leukapheresis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Structuring of a Lung Cancer Screening Program Including Clinical, Radiological and Biological Phenotyping Useful for the Development of Individualized Risk Prediction Tools: PREVALUNG ETOILE
Status: ACTIVE_NOT_RECRUITING
Conditions: Smoking-related Pathology|Atheroma|Chronic Bronchitis|Non-progressive Cancer > 5 Years|Lung Cancer
Interventions: DEVICE: thoracic scan Low dose|BIOLOGICAL: BLOOD SAMPLE|BIOLOGICAL: FECES SAMPLE
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: To Research the Relation Between Neonatal Morbidities and Poor Outcome in Preterm Infants
Status: COMPLETED
Conditions: Preterm Infant|Morbidity;Infant|Outcome, Fatal
Interventions: DIAGNOSTIC_TEST: Mental Development Index;Auditory Brainstem Response;okineticnystagmus
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: LUPUS Brain: tACS to Target the Neurophysiology of Depression, Cognitive Deficits, and Pain in Patients With SLE
Status: TERMINATED
Conditions: Systemic Lupus Erythematosus|Depression
Interventions: DEVICE: XCSITE100 Stimulator - Individualized theta-tACS|DEVICE: XCSITE100 Stimulator - Individualized alpha-tACS|DEVICE: XCSITE100 Stimulator - Active Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Clinical Utility Assay as a Biomarker for Gastroenteropancreatic and Lung Neuroendocrine Tumors
Status: COMPLETED
Conditions: Gastroenteropancreatic Neuroendocrine Tumor|Lung Neuroendocrine Neoplasm
Interventions: PROCEDURE: NETest
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: CC-11050 in Human Immunodeficiency Virus-1-Infected Adults With Suppressed Plasma Viremia on Antiretroviral Therapy (APHRODITE)
Status: COMPLETED
Conditions: HIV, Inflammation
Interventions: DRUG: Assess Safety|DRUG: Effect of drug on viral load|DRUG: Effect of drug on T-cell count|DRUG: Effect of drug on inflammatory biomarkers
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Enteric-coated Mycophenolate Sodium in Heart Transplant Recipients
Status: COMPLETED
Conditions: Patients Successfully Completing the 12-month Treatment Period of the Core Study (de Novo Heart Recipients) Who Were Interested of Being Treated With EC-MPS
Interventions: DRUG: EC-MPS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Boswellia Sacra as an Intracanal Medicament on Postoperative Pain Intensity and Bacterial Load Reduction
Status: RECRUITING
Conditions: Intervention
Interventions: OTHER: Boswellia Sacra
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acute Effects of Kinesiology Taping in Handball Players
Status: COMPLETED
Conditions: Kinesiology Taping
Interventions: PROCEDURE: Kinesiology Taping|PROCEDURE: Placebo Taping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Comparison Between Natural and Artificial Cycle in Recipient Oocyte Patients
Status: UNKNOWN
Conditions: Infertility
Interventions: OTHER: observation natural cycle|DRUG: Agonist GnRH; estradiol Valerate; progesterone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Baricitenib to Maintain of Remission
Status: RECRUITING
Conditions: Lupus or SLE|Nephritis
Interventions: DRUG: Baricitinib 4 MG|DRUG: Baricitinib 2 MG|DRUG: MMF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial to Evaluate the Safety and Immunogenicity of a 20-valent Pneumococcal Conjugate Vaccine in Pneumococcal Vaccine-naïve Adults
Status: COMPLETED
Conditions: Pneumococcal Disease
Interventions: BIOLOGICAL: 20vPnC|BIOLOGICAL: 13vPnC|BIOLOGICAL: PPSV23|OTHER: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Managing Aftercare for Stroke (MAS): MAS-II - A Longitudinal Complex-interventional Study in Post-rehabilitation Stroke Patients
Status: COMPLETED
Conditions: Stroke
Interventions: OTHER: comprehensive multidisciplinary stroke care
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Effects of AMPC in the Treatments of Refractory or Relapsed AML
Status: UNKNOWN
Conditions: Acute Myeloid Leukaemia Recurrent
Interventions: BIOLOGICAL: Autologous Multi-lineage Potential Cells (AMPC)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 18F-Fibroblast Activation Protein Inhibitor ([18F]FAPI-74) PET Imaging for Cancer Detection
Status: NOT_YET_RECRUITING
Conditions: Pancreatic Ductal Adenocarcinoma|Cholangiocarcinoma|Gastric Cancer|Bladder Cancer|Hepatocellular Carcinoma|Pheochromocytoma|Ovarian Cancer
Interventions: DRUG: [18F]FAPI-74|DRUG: [18F]FDG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Electronic-health Application To Measure Outcomes REmotely Clinical Trial
Status: COMPLETED
Conditions: Neurodegenerative Disease|Weight Loss|Amyotrophic Lateral Sclerosis|Parkinson's Disease|Huntington's Disease|Cachexia
Interventions: BEHAVIORAL: In-Person Nutritional Counseling by a Registered Dietitian|BEHAVIORAL: Nutritional counseling using an e-Health Application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Potential of a Low Glutamate Diet as a Treatment for Pediatric Epilepsy
Status: COMPLETED
Conditions: Epilepsy in Children|Epilepsy in Youth|Randomized Controlled Trial|Refractory Epilepsy|Diet Intervention
Interventions: OTHER: Low Glutamate diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Novel Lung Imaging in Adults Undergoing Radiation Therapy to Assess for Radiation Pneumonitis
Status: RECRUITING
Conditions: Lung Cancer|Breast Cancer|Mediastinum Lesion|Radiation Pneumonitis
Interventions: RADIATION: 4D Computed Tomography (CT)|RADIATION: Cone Beam CT|RADIATION: Low-dose Cinefluorography|DEVICE: Pulmonary Function Tests
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Detection of CardioRespiratory Events Using Acoustic Monitoring in Preterm Infants on CPAP
Status: RECRUITING
Conditions: Apnea of Prematurity
Interventions: DEVICE: Respiratory Acoustic Sensors|DEVICE: Nasal thermistor|DEVICE: Respiratory Inductive Plethysmography|DEVICE: Pneumotachometer
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Generic Zoledronic Acid Versus Original Zoledronic Acid in Postmenopausal Osteoporotic Women
Status: UNKNOWN
Conditions: Osteoporosis, Postmenopausal
Interventions: DRUG: Generic Zoledronic Acid|DRUG: Original Zoledronic Acid|DIETARY_SUPPLEMENT: calcium|DIETARY_SUPPLEMENT: vitamin D
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating the Effect of Multiple Doses of Itraconazole on the Drug Lu AF35700 in Healthy Young Men and Women
Status: COMPLETED
Conditions: Cytochrome P450 Interaction
Interventions: DRUG: Lu AF35700|DRUG: Itraconazole (200 mg)|DRUG: Itraconazole (300 mg)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single Arm Study of Induction Chemoradiotherapy Combined With Surgery in the Treatment of Locally Advanced SNMM
Status: RECRUITING
Conditions: Mucosal Melanoma|Sinonasal Melanoma
Interventions: PROCEDURE: endoscopic surgery|RADIATION: intensity-modulated radiation therapy or volume of rotating intensity-modulated radiotherapy or Proton or heavy ion radiation therapy|DRUG: Chemotherapy drug
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevention of Pneumococcal Infections: Impact Collaborative Medico-pharmaceutical Care Structured to Improve Vaccination Coverage of Patients at Risk.
Status: RECRUITING
Conditions: Streptococcus Pneumoniae Infection
Interventions: OTHER: Structured medico-pharmaceutical collaboration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Targeting Spreading Depolarization After Chronic Subdural Hematoma Surgery (TASD)
Status: WITHDRAWN
Conditions: Chronic Subdural Hematoma
Interventions: DRUG: Memantine Hydrochloride|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of MBSR in Improving Immune Response to Human Papillomavirus in Patients With Cervical Dysplasia
Status: COMPLETED
Conditions: Cervical Cancer|Precancerous Condition
Interventions: BEHAVIORAL: Mindfulness-Based Stress Reduction|BEHAVIORAL: Healthy Lifestyles
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: OSA-18 in Children With Mild Obstructive Sleep Apnea: Can it be a Helpful Decision Making Tool?
Status: RECRUITING
Conditions: Apnea, Obstructive Sleep|Obstructive Sleep Apnea
Interventions: OTHER: OSA-18 Survey|OTHER: Decisional Conflict (DCS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: An Open-label Safety and Tolerability Study of Nusinersen (ISIS 396443) in Participants With Spinal Muscular Atrophy Who Previously Participated in ISIS 396443-CS1 (NCT01494701)
Status: COMPLETED
Conditions: Spinal Muscular Atrophy
Interventions: DRUG: nusinersen
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Alitretinoin vs Cyclosporine in Severe Recurrent Vesicular Hand Eczema
Status: UNKNOWN
Conditions: Hand Eczema
Interventions: DRUG: Alitretinoin|DRUG: cyclosporin A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PRORAD-5 PROstate RADiation in 5 Fractions: Phase Ib Five Fraction Radiotherapy for Patients With Advanced Prostate Cancer
Status: RECRUITING
Conditions: Advanced Prostate Cancer
Interventions: DEVICE: Stereotactic Body Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Observational Study of Mircera (Methoxy Polyethylene Glycol-Epoetin Beta) in Stage III-IV Chronic Kidney Disease Patients Not on Dialysis With Renal Anemia
Status: COMPLETED
Conditions: Anemia
Interventions: DRUG: C.E.R.A.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Home Visits to Optimize Medical and Educational Success Among Sacramento Schoolchildren With Asthma
Status: COMPLETED
Conditions: Asthma|Chronic School Absenteeism
Interventions: BEHAVIORAL: Home Visit|BEHAVIORAL: Standard Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study to Assess the Efficacy, Safety, and Tolerability of NOC-110 in Adults With Refractory or Unexplained Chronic Cough
Status: NOT_YET_RECRUITING
Conditions: Refractory or Unexplained Chronic Cough
Interventions: DRUG: NOC-110|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics, Mass Balance, and Metabolism of [14C]HSK31679 in Healthy Adult Male Volunteers.
Status: ACTIVE_NOT_RECRUITING
Conditions: Healthy
Interventions: DRUG: [14C]HSK31679
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacodynamics of Tafluprost 0.0015% Eye Drops: a Comparison Between the Preserved and Unpreserved Formulation
Status: COMPLETED
Conditions: Open-Angle Glaucoma|Ocular Hypertension
Interventions: DRUG: Tafluprost 0.0015%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Perioperative Chemotherapy Plus Toripalimab for dMMR Locally Advanced Gastric or Esophagogastric Junction Adenocarcinoma
Status: RECRUITING
Conditions: Adenocarcinoma of the Stomach|Adenocarcinoma of Esophagogastric Junction|Mismatch Repair Deficiency
Interventions: DRUG: Toripalimab|DRUG: Oxaliplatin|DRUG: S1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study of the Safety and Efficacy of a Wearable Device (CLS UF) That Delivers Continuous Administration of Glucose to Recirculated Peritoneal Dialysis Fluid for the Purpose of Ultrafiltration in Patients With Congestive Heart Failure
Status: TERMINATED
Conditions: Heart Failure|Cardio-Renal Syndrome
Interventions: DEVICE: CLS UF
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study to Evaluate Absorption, Metabolism and Excretion of Single-dose [14C]-Saroglitazar in Healthy Male Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Saroglitazar magnesium
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Laser Therapy for Venous Leg Ulcers
Status: RECRUITING
Conditions: Venous Leg Ulcer|Varicose Ulcer|Stasis Ulcer
Interventions: DEVICE: High Intensity Laser Therapy|OTHER: Standard Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Learn How Safe Study Drug BAY2413555 is, How it Affects the Body, and How it Moves Into, Through, and Out of the Body Over 4 Weeks of Use in Participants With Heart Failure and Implanted Cardiac Defibrillator or Cardiac Resynchronization Devices (ICD/CRT)
Status: TERMINATED
Conditions: Chronic Heart Failure
Interventions: DRUG: BAY2413555 Dose 1|DRUG: BAY2413555 Dose 2|DRUG: Placebo to BAY2413555
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Myocardial Viability by Means of Low-dose Dobutamine Gated SPECT (the DOGS Study)
Status: COMPLETED
Conditions: Coronary Arteriosclerosis|Heart Failure, Congestive|Myocardial Infarction|Myocardial Ischemia|Myocardial Stunning
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Allogenic Adipose Tissue-Derived Mesenchymal Progenitor Cells for the Treatment of Knee Osteoarthritis
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: BIOLOGICAL: Mesenchymal progenitor cells|BIOLOGICAL: No mesenchymal progenitor cells
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Study of Osimertinib in Combination With Selumetinib in EGFR Inhibitor naïve Advanced EGFR Mutant Lung Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: Osimertinib|DRUG: Selumetinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial Cream D
Status: NOT_YET_RECRUITING
Conditions: Incontinence-associated Dermatitis|Moisture Associated Skin Damage (MASD) (E.G., Incontinence-Associated Dermatitis [IAD], Perspiration, Drainage)|Intertrigo
Interventions: OTHER: Cream D|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Erector Spinae Plane Block in Scoliotic Adolescents
Status: COMPLETED
Conditions: Scoliosis Idiopathic|Scoliosis; Adolescence|Erector Spinae Plane Block
Interventions: PROCEDURE: Erector Spinae Plane Block|DRUG: Fentanyl|DRUG: additional Fentanyl|DRUG: Morphine|DRUG: rescue Morphine|DRUG: pethidine|DRUG: Ketorolac|DRUG: Acetaminophen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Culturally-Informed Counseling in Latinas at High Risk for Hereditary Breast or Ovarian Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: No Evidence of Disease|BRCA1 Syndrome|BRCA2 Syndrome|Hereditary Female Breast Carcinoma|Hereditary Ovarian Carcinoma
Interventions: OTHER: questionnaire administration|OTHER: survey administration|OTHER: counseling intervention|OTHER: educational intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Clinical Implication of Atrial Fibrillation Detection Using Wearable Device in Patients With Cryptogenic Stroke
Status: RECRUITING
Conditions: Atrial Fibrillation|Ischemic Stroke|Transient Ischemic Attack
Interventions: DEVICE: Discontinuous monitoring|DEVICE: Continuous single-lead ECG Patch|DEVICE: 24-hour Holter monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: A Study to Evaluate the Effect of Repeat Oral Doses of YM443 on Cardiac Repolarization in Healthy Adults
Status: COMPLETED
Conditions: Functional Dyspepsia
Interventions: DRUG: YM443|DRUG: Placebo|DRUG: Moxifloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: The EVICEL® Neurosurgery Phase III Study
Status: COMPLETED
Conditions: Cerebrospinal Fluid Leak
Interventions: BIOLOGICAL: EVICEL Fibrin Sealant|DEVICE: Hydrogel sealant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Cellular Therapy for Type 1 Diabetes Using Mesenchymal Stem Cells
Status: RECRUITING
Conditions: Diabetes Mellitus, Type 1
Interventions: BIOLOGICAL: Mesenchymal Stem Cells (MSCs)|OTHER: Placebo Infusion (Plasmalyte A with 0.5% human serum albumin)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transdermal (TDS) Oxybutynin (Oxytrol(r)) in Overactive Bladder
Status: COMPLETED
Conditions: Overactive Bladder|Urinary Incontinence|Quality of Life
Interventions: DRUG: oxybutynin transdermal delivery system (Oxytrol(r))
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dietary Oxalate and Innate Immunity in Kidney Stone Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Kidney Stone
Interventions: DIETARY_SUPPLEMENT: Low Oxalate Diet|DIETARY_SUPPLEMENT: High Oxalate Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of the Effect of an Ongoing Treatment With Alendronate or a Drug Holiday on the Fracture Risk in Osteoporotic Patients With Bisphosphonate Long Term Therapy
Status: TERMINATED
Conditions: Osteoporosis
Interventions: DRUG: Alendronate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Effectiveness of Fluconazole Versus SCH 56592 to Treat Thrush in HIV-Positive Patients
Status: COMPLETED
Conditions: Candidiasis, Oral|HIV Infections
Interventions: DRUG: Posaconazole|DRUG: Fluconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Follow-up Protocol on the Outcome of Frozen-thawed Embryo Transfer Cycles From Clinical Trial P05690 (P05711)
Status: COMPLETED
Conditions: In Vitro Fertilization
Interventions: DRUG: corifollitropin alfa|BIOLOGICAL: recFSH (follitropin alfa)|DRUG: gonadatropin releasing hormone (GnRH) antagonist ganirelix|DRUG: human chorion gonadatropin (hCG)|BIOLOGICAL: progesterone|DRUG: placebo-recFSH (follitropin alfa)|DRUG: placebo-corifollitropin alfa|BIOLOGICAL: open-label recFSH
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Topical Ophthalmic AGN-195263 for the Treatment of Evaporative Dry Eye
Status: TERMINATED
Conditions: Dry Eye Syndromes
Interventions: DRUG: AGN-195263|DRUG: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of the Timing of Cataract Surgery on Complications in Patients With Bilateral Congenital Cataracts
Status: COMPLETED
Conditions: Cataract
Interventions: PROCEDURE: Phacomulsification lens removal cataract surgery without Intraocular lens(IOL) implantation at the age of 3month of the patients|PROCEDURE: Phacomulsification lens removal cataract surgery without Intraocular lens(IOL) implantation at the age of 6 month of the patients|DRUG: Subconjunctival dexamethasone and general anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Leflunomide for the Treatment of High-Risk Smoldering Multiple Myeloma in African-American and European-American Patients
Status: RECRUITING
Conditions: Smoldering Plasma Cell Myeloma
Interventions: DRUG: Cholestyramine|DRUG: Leflunomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Combined Spinal-Epidural Versus Traditional Labor Epidural
Status: COMPLETED
Conditions: Labour Pain
Interventions: DRUG: Bupivacaine and Fentanyl (for CSE)|DRUG: Bupivacaine and Fentanyl (for traditional epidural)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of Neuromuscular Stimulation and Mindfulness Breathing in Patients With Stroke
Status: RECRUITING
Conditions: Stroke
Interventions: OTHER: neuromuscular stimulation ,mindfulness breathing and traditional physiotherapy program|OTHER: traditional physiotherapy program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Ultrasound Guided Rectus Sheath Block on Post Operative Quality of Recovery
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: PROCEDURE: rectus sheath block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Prehabilitation Via a Mobile Application in Oesophago-gastric Cancer
Status: NOT_YET_RECRUITING
Conditions: Oesophageal Cancer|Gastric Cancer|Prehabilitation|mHealth Application
Interventions: DEVICE: Asensei app
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Use of Recombinant Adenovirus Therapy to Treat Localized Prostate Cancer
Status: COMPLETED
Conditions: Localized Prostate Cancer
Interventions: DRUG: Ad5-SGE-REIC/Dkk3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Bronchial Thickness Using MRI in Asthma
Status: UNKNOWN
Conditions: Asthma
Interventions: DIAGNOSTIC_TEST: Magnetic Resonance Imaging (MRI) with Ultrashort Echo Time (UTE)|DIAGNOSTIC_TEST: Computed tomography (CT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Breast Milk Odor on the Pain and Stress Level of the Newborn Endotracheal Aspiration Procedure
Status: COMPLETED
Conditions: Endotracheal Aspiration
Interventions: BEHAVIORAL: the smell of breast milk
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study In Airway Physiology In Children SERETIDE DISKUS ® Inhlaer and FLIXOTIDE® Inhaler Are Trademarks of GSK Group of Companies.
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Salmeterol/fluticasone propionate|DRUG: Fluticasone propionate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Monitoring Postprandial Blood Glucose and Insulin in Fruit Snacks
Status: RECRUITING
Conditions: Blood Glucose|Blood Insulin
Interventions: DIETARY_SUPPLEMENT: Fruit snack 1|DIETARY_SUPPLEMENT: Fruit snack 2|DIETARY_SUPPLEMENT: Fruit snack 3|DIETARY_SUPPLEMENT: Fruit snack 4|DIETARY_SUPPLEMENT: Fruit snack 5|DIETARY_SUPPLEMENT: Confection control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Perioperative Use of Glycopyrrolate on Lung Function in Patients Under General Anesthesia
Status: RECRUITING
Conditions: Glycopyrrolate
Interventions: DRUG: Glycopyrrolate|OTHER: normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: High Dose Atorvastatin for Preventing Contrast-induced Nephropathy
Status: COMPLETED
Conditions: Contrast-Induced Nephropathy
Interventions: DRUG: Atorvastatin|DRUG: Placebo|DRUG: 0.9% sodium chloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Gefitinib in Treating Patients With Recurrent or Metastatic Esophageal or Gastroesophageal Junction Cancer
Status: COMPLETED
Conditions: Esophageal Cancer
Interventions: DRUG: ZD1839
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Reinduction and Second Stop of TKI With Ponatinib in CML in Molecular Response (ResToP)
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Myeloid Leukemia, Chronic Phase
Interventions: DRUG: Ponatinib 15 MG|DRUG: Acetylsalicylic acid 100 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Effect of Two Anaesthesia Methods in Preventing Perioperative Myocardial Infarcation in Patients With Cardiac Risk Undergoing Total Knee Arthroplasty
Status: COMPLETED
Conditions: Myocardial Ischaemia
Interventions: PROCEDURE: general anaesthesia|PROCEDURE: spinal anaesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Randomized Controlled Trial of Vaginal Progesterone in Women With Threatened Preterm Labor
Status: TERMINATED
Conditions: Obstetric Labor, Premature
Interventions: DRUG: Vaginal progesterone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Aggressive Fluid Hydration for the Prevention of Post-ERCP Pancreatitis
Status: COMPLETED
Conditions: Pancreatitis
Interventions: DRUG: Lactated Ringer's solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of the Safety of Adjunct Brexpiprazole in Elderly Patients With Major Depressive Disorder and an Inadequate Response to Antidepressant Treatment
Status: COMPLETED
Conditions: Major Depression Disorder
Interventions: DRUG: Adjunct brexpiprazole|DRUG: ADT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Evaluate the Chronic Efficacy of OC-01 Nasal Spray on Signs of Dry Eye Disease (The MYSTIC Study)
Status: COMPLETED
Conditions: Dry Eye Disease
Interventions: DRUG: OC-01 0.1% 0.6 mg/ml|DRUG: OC-01 (varenicline) nasal spray: 0.2 % (1.2 mg/ml)|OTHER: placebo comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Melphalan and Palifermin in Treating Patients Undergoing An Autologous Peripheral Stem Cell Transplant for Stage II or III Multiple Myeloma
Status: COMPLETED
Conditions: Mucositis|Multiple Myeloma
Interventions: BIOLOGICAL: Palifermin|DRUG: melphalan|OTHER: questionnaire administration|PROCEDURE: autologous peripheral blood stem cell transplantation|OTHER: quality-of-life assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of Education Given to Hemodialysis Patients With Pecha Kuka Method on Attitude Towards Diet Therapy and Compliance With Fluid Restriction
Status: RECRUITING
Conditions: Hemodialysis Patients
Interventions: BEHAVIORAL: pecha kucha
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Eccentric Training Effects on Hamstrings Structure, Strength, and Sprint Performance
Status: COMPLETED
Conditions: Exercise Training|Sport|Running|Ultrasound Imaging|Elastography|Healthy
Interventions: DIAGNOSTIC_TEST: Ultrasound imaging|OTHER: Hamstring Eccentric Strength Testing|OTHER: Maximal 60 m Sprint|OTHER: Romanian Deadlift|OTHER: Nordic hamstring exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Efficacy of Extended-Release Liposomal Bupivacaine for Post-Operative Urogynecologic Surgery
Status: UNKNOWN
Conditions: Postoperative Pain
Interventions: DRUG: Extended-Release liposomal bupivacaine (Exparel)|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Virtual Reality Versus Motor Imagery Versus Routine Physical Therapy in Patients With Parkinson's Disease.
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: OTHER: VR with Routine physical therapy and Virtual reality|OTHER: Motor Imagery with Routine physical therapy|OTHER: Routine physical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Deep Cervical Training Combined With Mobilization Techniques on Forward Head Posture
Status: RECRUITING
Conditions: Forward Head Posture
Interventions: OTHER: Deep Cervical Training|OTHER: Deep cervical training + Upper cervical mobilization group|OTHER: Deep cervical training + Upper thoracic mobilization group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Patient Insights Following Use of LEO 90100 Aerosol Foam and Daivobet® Gel in Subjects With Psoriasis Vulgaris
Status: COMPLETED
Conditions: Psoriasis Vulgaris
Interventions: DRUG: LEO 90100 Aerosol Foam|DRUG: Daivobet® gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Efficacy of Partial Covered Double Bare Metal Stent Compared to Uncovered Double Bare Metal Stent in Malignant Biliary Obstruction
Status: UNKNOWN
Conditions: Malignant Tumor
Interventions: DEVICE: SEMS(self-expandable metallic stent)|DEVICE: Stenting by ERCP (endoscopic retrograde cholangiopancreatography)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Efficacy and Dose-response Study of BMS-986001 in Subjects With HIV-1 Infection Who Are Treatment-naive
Status: TERMINATED
Conditions: HIV-1 Infection
Interventions: DRUG: BMS-986001|DRUG: BMS-986001|DRUG: BMS-986001|DRUG: Placebo matching with BMS-986001|DRUG: Efavirenz|DRUG: Lamivudine|DRUG: Tenofovir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Optimizing Delivery of a Behavioral Cancer Pain Intervention Using a SMART
Status: COMPLETED
Conditions: PCST-Full (Pain Coping Skills Training)|PCST-Brief
Interventions: BEHAVIORAL: Pain Coping Skills Training Full|BEHAVIORAL: Pain Coping Skills Brief
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Does Doxazosin Attenuate Stress-induced Smoking and Improve Clinical Outcomes?
Status: COMPLETED
Conditions: Smoking
Interventions: DRUG: Doxazosin 4mg/day|DRUG: Placebo|DRUG: Doxazosin 8mg/day
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pain and Narcotic Usage After Orthopaedic Surgery
Status: COMPLETED
Conditions: Fractures, Closed|Pain, Postoperative|Pain Catastrophizing|Pain, Acute|Analgesia|Opioid Use|Acceptance and Commitment Therapy|Orthopedics|Analgesics, Opioid|Text Messaging
Interventions: BEHAVIORAL: Acceptance and Commitment Therapy Delivered via an Automated Mobile Messaging Robot
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: BOTOX® (Botulinum Toxin Type A) as Headache Prophylaxis in Chinese Participants With Chronic Migraine
Status: WITHDRAWN
Conditions: Migraine Disorders
Interventions: BIOLOGICAL: botulinum toxin Type A|DRUG: placebo (sodium chloride 0.9 mg)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Acute Effects of Stimulant Medication in College Students With ADHD
Status: RECRUITING
Conditions: Attention Deficit Hyperactivity Disorder|Stimulant Use|Working Memory|Change in Sustained Attention|Mood
Interventions: DRUG: Adderall IR 10mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Vitreous Levels of Acular LS 0.04%, Xibrom 0.09%, and Nevanac 0.1%
Status: COMPLETED
Conditions: Vitrectomy
Interventions: DRUG: Nepafenac|DRUG: Ketorolac LS, Bromfenac
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose:
Clinical trial: Dexmedetomidine in Spinal Anesthesia Decreasing Post Spinal Shivering in Caesarean Section
Status: RECRUITING
Conditions: Post Spinal Shivering
Interventions: DRUG: Dexmedetomidine Injection [Precedex],,,|DRUG: Fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Testing a Transdiagnostic TMS Treatment Target
Status: RECRUITING
Conditions: Major Depressive Disorder|Depression|Psychiatric Disorder|Mood Disorders|Mental Disorder|Anxiety Disorders|OCD|PTSD
Interventions: PROCEDURE: transcranial magnetic stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Surgical Excision Versus Photodynamic Therapy and Topical 5-fluorouracil in Treatment of Bowen's Disease
Status: RECRUITING
Conditions: Bowen's Disease
Interventions: DRUG: Methyl Aminolevulinate (Mal) for Topical Administration, 16.8%, 1 Gram|DRUG: 5Fluorouracil|OTHER: Surgical excision
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Topical Cantharidin for the Treatment of Molluscum Contagiosum, Phase 2
Status: COMPLETED
Conditions: Molluscum Contagiosum
Interventions: DRUG: Cantharidin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testing the Addition of Whole Brain Radiotherapy Using a Technique That Avoids the Hippocampus to Stereotactic Radiosurgery in People With Cancer That Has Spread to the Brain and Come Back in Other Areas of the Brain After Earlier Stereotactic Radiosurgery
Status: RECRUITING
Conditions: Anatomic Stage IV Breast Cancer AJCC v8|Metastatic Breast Carcinoma|Metastatic Digestive System Carcinoma|Metastatic Lung Non-Small Cell Carcinoma|Metastatic Malignant Neoplasm in the Brain|Metastatic Melanoma|Metastatic Renal Cell Carcinoma|Prognostic Stage IV Breast Cancer AJCC v8|Recurrent Brain Neoplasm|Stage IV Lung Cancer AJCC v8|Stage IV Renal Cell Cancer AJCC v8|Stage IVA Lung Cancer AJCC v8|Stage IVB Lung Cancer AJCC v8
Interventions: DRUG: Memantine|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration|RADIATION: Stereotactic Radiosurgery|RADIATION: Whole-Brain Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: CAR-T Cells for HIV Infection
Status: RECRUITING
Conditions: HIV Infections
Interventions: DRUG: Cyclophosphamide|BIOLOGICAL: LVgp120duoCAR-T cells, low dose|BIOLOGICAL: LVgp120duoCAR-T cells, high dose|OTHER: Analytic Treatment Interruption
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects and Safety of Menthol on Blood Pressure and Metabolic Parameters in Prehypertensive and Mild Hypertensive Patients
Status: COMPLETED
Conditions: Hypertension|Prehypertension
Interventions: DRUG: Menthol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Safety and Tolerability of JNJ-67670187 in Healthy Participants
Status: COMPLETED
Conditions: Healthy
Interventions: BIOLOGICAL: JNJ-67670187|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: A Study of the Efficacy and Safety of DMX-200 in Patients With FSGS Who Are Receiving an ARB
Status: RECRUITING
Conditions: FSGS
Interventions: DRUG: DMX-200|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant FOLFIRINOX Regimen in Patients With Non-metastatic Pancrease Cancer
Status: UNKNOWN
Conditions: Pancreas Cancer|Localized Pancreas Cancer|Non-metastatic Pancreas Cancer
Interventions: DRUG: FOLFIRINOX Regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability Study of MBS2320 in Healthy Subjects and Subjects With Rheumatoid Arthritis
Status: COMPLETED
Conditions: Arthritis, Rheumatoid
Interventions: DRUG: MBS2320|DRUG: Placebo|DRUG: Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Acute Effect of Isometric Versus Isotonic Resistance Exercise in Patients With Patellar Tendinopathy
Status: COMPLETED
Conditions: Patellar Tendinitis
Interventions: OTHER: Isotonic Exercise|OTHER: Isometric exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Antimicrobial Photodynamic Therapy in Chronic Periodontitis and Diabetes Mellitus
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus|Prediabetic State|Chronic Periodontitis
Interventions: DRUG: Indocyanine green
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Efficacy and Safety Study of Composite Gel Containing Black Raspberry Extract in Removing HPV From Patients With Cervical Intraepithelial Neoplasia(CIN) After Cervical Conization
Status: UNKNOWN
Conditions: Cervical Intraepithelial Neoplasia|HPV
Interventions: BIOLOGICAL: Composite Gel Containing Black Raspberry|BIOLOGICAL: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Milk and Yogurt Supplementation on Bone Health, Body Composition, and Gut Microbiota in Canadian Young Adults
Status: RECRUITING
Conditions: Osteoporosis|Obesity
Interventions: OTHER: Habitual Diet + Milk|OTHER: Habitual Diet + Yogurt
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION