pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Valacyclovir in Preventing Cytomegalovirus Infection in Patients Who Are Undergoing Donor Stem Cell Transplantation
Status: COMPLETED
Conditions: Cancer
Interventions: DRUG: acyclovir|DRUG: acyclovir sodium|DRUG: valacyclovir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Report Cards and Feedback for PCCE
Status: RECRUITING
Conditions: Behavioral Economics|Primary Health Care|Health Maintenance
Interventions: BEHAVIORAL: Standard Communication Email|BEHAVIORAL: Personalized Report Card Email|BEHAVIORAL: Bottom-Up Framing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Pilot Study of Nilogen 3D-EX and Its Ability to Predict Therapeutic Response to Anti-PD1 or Anti-PDL1 in NSCLC
Status: UNKNOWN
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: Nivolumab|DIAGNOSTIC_TEST: 3D-EX|OTHER: Evaluation of Response by RECIST
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Long Term Safety and Tolerability of QVA149 Versus Tiotropium in Japanese Patients With Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: DRUG: QVA149|DRUG: Tiotropium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Quality of Life in Patients Undergoing Radiation Therapy for Primary Lung Cancer, Head and Neck Cancer, or Gastrointestinal Cancer
Status: COMPLETED
Conditions: Anal Cancer|Colorectal Cancer|Esophageal Cancer|Extrahepatic Bile Duct Cancer|Gallbladder Cancer|Gastric Cancer|Head and Neck Cancer|Liver Cancer|Lung Cancer|Pancreatic Cancer|Small Intestine Cancer
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Invasive Versus Non-invasive Approach in Symptomatic Patient With Non-High Risk Coronary Artery Stenosis
Status: RECRUITING
Conditions: Coronary Artery Disease
Interventions: DIAGNOSTIC_TEST: Invasive coronary angiography|DIAGNOSTIC_TEST: Non-invasive functional test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Influences of Propofol and Sevoflurane Anesthesia in Ovarian Cancer (Anesthetics)
Status: RECRUITING
Conditions: Ovarian Cancer
Interventions: DRUG: Propofol 1%|DRUG: Sevoflurane/Ultane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study With a Initial Treatment Period Followed by a Randomized-withdrawal Period to Evaluate the Efficacy and Safety of Bimekizumab in Adult Subjects With Moderate to Severe Chronic Plaque Psoriasis
Status: COMPLETED
Conditions: Chronic Plaque Psoriasis|Moderate to Severe Chronic Plaque Psoriasis|Psoriatic Arthritis
Interventions: DRUG: Bimekizumab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Three-dimensional Power Doppler in the Diagnosis of Endometrial Lesions in Patients With Postmenopausal Bleeding
Status: UNKNOWN
Conditions: Postmenopausal Bleeding
Interventions: DIAGNOSTIC_TEST: 3 dimensional ultrasonography and Doppler
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of Dovitinib (TKI258) in Adenoid Cystic Carcinoma
Status: COMPLETED
Conditions: Adenoid Cystic Carcinoma
Interventions: DRUG: Dovitinib (TKI258)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of Stellate Ganglion Block in Treatment of Patients With Advanced Primary Parkinson's Disease
Status: RECRUITING
Conditions: Stellate Ganglion|Parkinson Disease
Interventions: DIAGNOSTIC_TEST: Treatment （Stellate ganglion block；Oral standard anti-Parkinson's drugs）|DIAGNOSTIC_TEST: Treatment （Oral standard anti-Parkinson's drugs）
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Abiraterone Acetate and Prednisone in Combination With Cabazitaxel in Patients With Prostate Cancer
Status: TERMINATED
Conditions: Prostate Cancer
Interventions: DRUG: Cabazitaxel with Abiraterone Acetate|DRUG: Cabazitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Safety and Tolerability of JNJ-61178104 in Healthy Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: JNJ-61178104 Intravenous|DRUG: JNJ-61178104 Subcutaneous|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Different Smoking Cessation Protocols: Nicotine Replacement, Motivational Interviewing (MI), Cognitive Behavioural Therapy (CBT) or Hypnotherapy in Cancer Patients Scheduled for Surgery
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer|Gynecologic Cancer|Digestive Cancer|Melanoma
Interventions: BEHAVIORAL: Motivational Interviewing (MI)|BEHAVIORAL: Cognitive Behavioural Therapy (CBT)|BEHAVIORAL: Hypnotherapy|DRUG: Nicotine Replacement Therapy (NRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of SARS-CoV-2 mRNA Vaccine(LVRNA009) as Heterologous Booster in Islamabad
Status: NOT_YET_RECRUITING
Conditions: SARS-CoV-2
Interventions: BIOLOGICAL: LVRNA009|BIOLOGICAL: CoronaVac®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Prospective Trial Of Osmolar Protocol Solution on Colonoscopy Outcomes and Patient Experience
Status: UNKNOWN
Conditions: Colonoscopy
Interventions: DIETARY_SUPPLEMENT: Complex Carbohydrate (PREcovery)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: To Evaluate the Immunogenicity and Safety of Sequential Immunization Schedules of Sabin IPV and bOPV
Status: COMPLETED
Conditions: Vaccination|Reaction - Vaccine
Interventions: BIOLOGICAL: Sabin-IPV+bOPV+bOPV|BIOLOGICAL: Sabin-IPV+Sabin-IPV+bOPV|BIOLOGICAL: Sabin-IPV+Sabin-IPV+Sabin-IPV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Phenoptin to Increase Phenylalanine Tolerance in Phenylketonuric Children on a Phenylalanine-restricted Diet
Status: COMPLETED
Conditions: Phenylketonurias
Interventions: DRUG: Sapropterin Dihydrochloride|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Physiotherapy Program in Scleroderma Patients
Status: COMPLETED
Conditions: Scleroderma|Systemic Sclerosis|Hand Rheumatism|Physiotherapy|Rehabilitation
Interventions: OTHER: Hand Therapy by Physiotherapist|OTHER: Hand Therapy as home program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ablation Strategies for Persistent Atrial Fibrillation Combined With Heart Failure
Status: RECRUITING
Conditions: Atrial Fibrillation|Heart Failure
Interventions: PROCEDURE: VOM ethanol chemical ablation and 2C3L|PROCEDURE: 2C3L
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Subcutaneous Implantable Defibrillator (S-ICD) System - CE Clinical Investigation
Status: COMPLETED
Conditions: ACC/AHA/NASPE Class 1, IIa or IIb Indications
Interventions: DEVICE: subcutaneous implantable defibrillator (S-ICD) system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Evaluation of the Effect of the Erchonia Corporation Violet Zerona® Z6 for Body Contouring
Status: COMPLETED
Conditions: Circumference Reduction
Interventions: DEVICE: Erchonia Violet Zerona Z6
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Inactive Vitamin D Supplementation in Non-Alcoholic Fatty Liver Disease Patients
Status: RECRUITING
Conditions: Non-Alcoholic Fatty Liver Disease
Interventions: DRUG: Cholecalciferol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: IIT2023-09-Chung-UpfrontTAD: Upfront TAD/SNB in Patients With Breast Cancer With Nodal Metastases
Status: RECRUITING
Conditions: Breast Cancer|Axillary Nodal Disease|Female Breast Cancer|Axilla; Breast|Mastectomy; Lymphedema|Tumor, Breast
Interventions: PROCEDURE: Breast Surgery (BCS or mastectomy) with TAD/SNB|RADIATION: Adjuvant Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of CPX-351 in Newly Diagnosed Elderly AML Patients
Status: COMPLETED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: CPX-351|DRUG: Cytarabine|DRUG: Daunorubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Regulation of Optic Nerve Head Blood Flow During Combined Changes in Intraocular Pressure and Arterial Blood Pressure
Status: WITHDRAWN
Conditions: Healthy
Interventions: PROCEDURE: Suction cup application|OTHER: Squatting
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Open-label Study of Dolutegravir (DTG) or Efavirenz (EFV) for Human Immunodeficiency Virus (HIV) - Tuberculosis (TB) Co-infection
Status: COMPLETED
Conditions: Infection, Human Immunodeficiency Virus|HIV Infections
Interventions: DRUG: DTG 50 mg|DRUG: EFV 600 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase-I, Dose Escalation Study of Recombinant Human Interleukin-18 (Sb-485232) Combined With Adoptive Transfer of Vaccine-Primed CD3/CD28-Costimulated Autologous T-Cells Following Lymphodepletion for Adult Patients With Recurrent Ovarian, Fallopian Tube or Primary Peritoneal Cancer
Status: WITHDRAWN
Conditions: Ovarian, Fallopian Tube and Peritoneal Cancer
Interventions: BIOLOGICAL: Vaccine---primed, CD3/CD28---costimulated autologous peripheral blood T---cells|BIOLOGICAL: SB---485232 (Human recombinant Interleukin---18)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: |Primary Purpose: TREATMENT
Clinical trial: NOWDx Test for the Detection of Antibodies to COVID-19 in Lay Persons
Status: TERMINATED
Conditions: COVID-19|SARS-CoV-2|Coronavirus
Interventions: DEVICE: NOWDx COVID-19 Test
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Functional Sparing of Salivary Glands Using MRI Sialography for Patients Undergoing Definitive Radiation Therapy for Head and Neck Cancers of the Oropharynx
Status: COMPLETED
Conditions: Head and Neck Cancer|Oropharynx Cancer|Xerostomia Due to Radiotherapy
Interventions: OTHER: Parotid-Sparing Head & Neck Radiation Guided by MRI Sialography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Serratus Anterior Plane Block for Pain Treatment After Video-Assisted Thoracoscopic Surgery
Status: COMPLETED
Conditions: Nerve Block
Interventions: PROCEDURE: Serratus Anterior Plane Block|DRUG: IV patient-controlled analgesia (PCA) tramadol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Dermal Matrix in Breast Reconstruction
Status: TERMINATED
Conditions: Breast Cancer
Interventions: PROCEDURE: DermaMatrix|PROCEDURE: standard of care tissue expander breast reconstruction surgery after mastectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Extension Study of JR-141 to Evaluate the Long-term Safety and Efficacy in Mucopolysaccharidosis Type II (Hunter Syndrome) Subjects
Status: ENROLLING_BY_INVITATION
Conditions: Mucopolysaccharidosis II
Interventions: DRUG: JR-141
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hippocampal-Sparing Prophylactic Cranial Irradiation in Pathologically Nodal Positive Non-Small-Cell Lung Cancer
Status: RECRUITING
Conditions: Non-Small-Cell Lung Cancer (NSCLC)|Brain Metastasis
Interventions: RADIATION: hippocampal-sparing WBRT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Continuous Versus Conventional Volume Management During CRRT (Continuous Renal Replacement Therapy)
Status: COMPLETED
Conditions: Continuous Renal Replacement Therapy
Interventions: DEVICE: use of continuous renal replacement machine for renal replacement|DEVICE: use of blood volume monitoring device in conjunction with machine used for continuous renal replacement to assess and determine volume removal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of Exercise in Water on Functional Fitness in People With Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson|Parkinson Disease|Neurologic Disorder
Interventions: OTHER: Exercise in water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of the Effect of AZD5069 in Patients With Bronchiectasis
Status: COMPLETED
Conditions: Bronchiectasis|Lung Disease|Respiratory Diseases
Interventions: DRUG: AZD5069|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fludarabine and Darbepoetin Alfa in Treating Older Patients With Chronic Lymphocytic Leukemia
Status: COMPLETED
Conditions: Chronic Lymphocytic Leukemia|Anemia
Interventions: BIOLOGICAL: Fludarabine plus Darbopoetin|DRUG: Fludarabine mono
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Campath, Rituximab, and Myfortic With Short-Course Calcineurin Inhibitor Therapy in Renal Transplanation
Status: TERMINATED
Conditions: Acute Rejection|Renal Transplantation
Interventions: DRUG: Campath-1H, rituximab, myfortic
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Single-Session Intervention for Adolescents and Young Adults With Internalizing Problems
Status: ACTIVE_NOT_RECRUITING
Conditions: Anxiety|Depressive Symptoms
Interventions: OTHER: Adolescent/Young Adult Self-Administered Web-Based Single-Session Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Impact of Renalof® Dietary Supplement on Upper Urinary Tract Stone Volume
Status: COMPLETED
Conditions: Calculus of Upper Urinary Tract (Disorder)
Interventions: DIETARY_SUPPLEMENT: Renalof 325mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Study of Osimertinib and S-1 in Treatment Resistant EGFR Mutant NSCLC
Status: RECRUITING
Conditions: NSCLC
Interventions: DRUG: Oral S-1 + Oral Osimertinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of 4% Articaine Terminal Anesthesia in the Lateral Jaw Region in Children
Status: COMPLETED
Conditions: Dental Caries|Primary Teeth|Inferior Alveolar Nerve|Anesthesia, Dental
Interventions: PROCEDURE: Tooth extraction of deciduous and permanent molars in children aged 5-18 years and mandibular premolars in children aged 10-18 years|PROCEDURE: Endodontic dental treatment of deciduous and permanent molars in children aged 5-18 years and mandibular premolars in children aged 10-18 years|PROCEDURE: Conservative tooth restoration of deciduous and permanent molars in children aged 5-18 years and mandibular premolars in children aged 10-18 years
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of Mitoxantrone Hydrochloride Liposome Injection in Subjects With Acute Myeloid Leukemia
Status: RECRUITING
Conditions: Relapsed or Refractory Acute Myeloid Leukemia
Interventions: DRUG: Mitoxantrone liposome|DRUG: Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Daily, Digital and Behavioral Tele-health Tapering Program for Perioperative Surgical Patients Exposed to Opioids and Benzodiazepines.
Status: COMPLETED
Conditions: Elective Spine Surgery Receiving Pre and/or Postoperative Pain Control With Opioids
Interventions: BEHAVIORAL: Opioid and Benzodiazepine Naive-patients|BEHAVIORAL: Opioid and Benzodiazepine Tolerant-patients
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunostimulating Interstitial Laser Thermotherapy in Malignant Melanoma
Status: TERMINATED
Conditions: Melanoma|Malignant Melanoma
Interventions: DEVICE: Immunostimulating Interstitial Laser Thermotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Efficacy of HepaStem in Urea Cycle Disorders Paediatric Patients (HEP002)
Status: COMPLETED
Conditions: Urea Cycle Disorders
Interventions: BIOLOGICAL: HepaStem
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Erectae Spinae Block Versus Intrathecal Morphine for Postoperative Analgesis in Lumbar Surgeries
Status: COMPLETED
Conditions: Post-operative|Analgesia
Interventions: OTHER: Ultrasound guided lumbar erectae spinae block|OTHER: Intrathecal Morphine injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Cohort Study of Bowel Function Following Robotic-assisted Laparoscopic Sacrocolpopexy
Status: COMPLETED
Conditions: Pelvic Organ Prolapse|Constipation|Bowel Dysfunction|Irritable Bowel Syndrome
Interventions: PROCEDURE: Robotic sacral colpopexy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Culturally Congruent HIV Risk Reduction App for Young Women, an Acceptability & Pilot Evaluation
Status: COMPLETED
Conditions: HIV|STDs
Interventions: BEHAVIORAL: Understanding Reproductive Health for Ladeez (GURHL) Code
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Clinical Study for Topical Lupeol in Acne
Status: COMPLETED
Conditions: Acne
Interventions: DRUG: Lupeol|DRUG: Placebo vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of an Investigational Drug, ASP3026, in Patients With Advanced Malignancies (Solid Tumors and B-Cell Lymphoma)
Status: COMPLETED
Conditions: Advanced Malignancies|Positive for Anaplastic Lymphoma Kinase|Positive for Proto-Oncogene Tyrosine-Protein Kinase ROS|Solid Tumor|B-Cell Lymphoma
Interventions: DRUG: ASP3026
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transcutaneous Electrical Spinal Stimulation to Restore Upper Extremity Functions in Spinal Cord Injury
Status: ACTIVE_NOT_RECRUITING
Conditions: Spinal Cord Injury Cervical|Upper Extremity Dysfunction
Interventions: DEVICE: Transcutaneous spinal stimulation|OTHER: Physical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Onapristone and Fulvestrant for ER+ HER2- Metastatic Breast Cancer After Endocrine Therapy and CDK4/6 Inhibitors (The SMILE Study)
Status: TERMINATED
Conditions: ER-positive Breast Cancer|HER2-negative Breast Cancer|Metastatic Cancer
Interventions: DRUG: Onapristone|DRUG: Fulvestrant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Point in Time of Radiotherapy for Patients With Biochemical Recurrent Prostate Carcinoma
Status: UNKNOWN
Conditions: Prostate Cancer|Recurrence
Interventions: DEVICE: PET/CT|RADIATION: Instant Radiotherapy according to guidelines|RADIATION: Radiotherapy after achievement of PSA marginal value
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Opioid Free Anaesthesia Versus Opioid Based Anesthesia for Laparscopic Cholecystectomy
Status: NOT_YET_RECRUITING
Conditions: Opioid Use
Interventions: PROCEDURE: opioid anaesthesia|PROCEDURE: Opioid free anaesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Optimizing Haploidentical Aplastic Anemia Transplantation (BMT CTN 1502)
Status: COMPLETED
Conditions: Severe Aplastic Anemia
Interventions: DRUG: Antithymocyte Globulin (ATG)|DRUG: Fludarabine|DRUG: Cyclophosphamide|RADIATION: Total Body Irradiation (TBI)|PROCEDURE: Haplo HSCT|DRUG: Tacrolimus|DRUG: Mycophenolate mofetil (MMF)|DRUG: G-CSF
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of a Single Ascending Dose Study of DS-7011a in Healthy Subjects
Status: COMPLETED
Conditions: Systemic Lupus Erythematosus
Interventions: DRUG: DS-7011a|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Improving COVID-19 Vaccine Uptake Among Black and Latino Youth
Status: COMPLETED
Conditions: COVID-19
Interventions: BEHAVIORAL: Culturally-Tailored COVID-19 Vaccine Uptake Intervention|BEHAVIORAL: Standard Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Metacognitive Training in the Older Adults With Depressive Symptoms (MCT-Silver)
Status: RECRUITING
Conditions: Depressive Symptoms
Interventions: BEHAVIORAL: Metacognitive Training for Depression in Later Life (MCT-Silver)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Simplified IMmunosuppressive Protocol Utilizing Low Dose EnvarsusXR
Status: RECRUITING
Conditions: Kidney Transplantation|Kidney Transplant Rejection
Interventions: DRUG: Twice-daily Tacrolimus|DRUG: Once-daily envarsus XR|DRUG: Induction Immunosuppression with Basiliximab or Rabbit Anti Thymoglobulin (rATG)|DRUG: Methylprednisolone, prednisone|DRUG: Mycophenolate mofetil (MMF) or Mycophenolic acid (MPA)|DRUG: Azathioprine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reduced Clavulanate Formulation of Amoxicillin-Clavulanate in Children 6-23 Months With Acute Otitis Media
Status: COMPLETED
Conditions: Acute Otitis Media
Interventions: DRUG: Amoxicillin-Clavulanate potassium
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Use of Deep Inspiration Breath Hold and Prone Irradiation to Decrease Cardiac Radiation Exposure
Status: COMPLETED
Conditions: Breast Cancer|Ductal Carcinoma in Situ|Invasive Breast Cancer
Interventions: OTHER: Deep Inspiration Breath Hold during Radiation|OTHER: Free breathing during radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Fractionated Radiosurgery for Painful Spinal Metastases
Status: COMPLETED
Conditions: Neoplasm Metastasis|Neoplastic Processes|Neoplasm Recurrence, Local|Neoplasm, Residual|Pain
Interventions: RADIATION: Radiosurgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Likeability, Safety, and Abuse Potential of NRP 104 in Adults With Histories of Stimulant Abuse
Status: COMPLETED
Conditions: Attention Deficit Disorder With Hyperactivity|Amphetamine-Related Disorders|Substance-Related Disorders
Interventions: DRUG: NRP104
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Study of LOR-253 HCl in Patients With Advanced or Metastatic Solid Tumours
Status: COMPLETED
Conditions: Advanced or Metastatic Solid Tumours
Interventions: DRUG: LOR-253 HCl
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Safety and Tolerability of Rotigotine Nasal Spray for the Acute Treatment of Parkinson Symptoms
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DRUG: Rotigotine nasal spray|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study on Ozone Autohemotherapy for the Treatment of Acute Ischemic Stroke
Status: COMPLETED
Conditions: Acute Ischemic Cerebrovascular Disease
Interventions: PROCEDURE: Oxygen|PROCEDURE: Ozone|PROCEDURE: Standard therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Acyclovir in Mechanically Ventilated Patients With Pneumonia and HSV-1 in BAL
Status: RECRUITING
Conditions: Pneumonia, Viral|Ventilator Associated Pneumonia|Community-acquired Pneumonia|Herpes Simplex|Hospital-acquired Pneumonia
Interventions: DRUG: Acyclovir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hormonal Effects of the Oral Gonadotropin Releasing Hormone (GnRH) Antagonist at Different Periods of the Menstrual Cycle
Status: UNKNOWN
Conditions: Ovulation; Failure or Lack of
Interventions: DRUG: Elagolix 200 MG Oral Tablet [Orilissa]
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: An Acupuncture Study for Prostate Cancer Survivors With Urinary Issues
Status: ACTIVE_NOT_RECRUITING
Conditions: Survivorship|Prostate Cancer
Interventions: PROCEDURE: Acupuncture|OTHER: Waitlist Control|OTHER: Questionnaires
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing Fully Covered, Self Expanding Metal Stent (FCSEMS) and Plastic Stents for EUS- Guided Drainage of WON
Status: WITHDRAWN
Conditions: Walled-off Necrosis
Interventions: DEVICE: Plastic Stent|DEVICE: Axios Fully Covered Self Expanding Metal Stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Spinal and Supra-Spinal Pain Mechanisms in Patients With Fibromyalgia
Status: COMPLETED
Conditions: Fibromyalgia|Pain
Interventions: DRUG: Capsaicin Patch 8% or 0.1% Capsaicin Cream|OTHER: Vehicle Patch
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of Camlipixant in Male and Female Healthy Participants and Participants With Hepatic Impairment Aged 18-75 Years of Age
Status: RECRUITING
Conditions: Cough
Interventions: DRUG: Camlipixant
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Removal of Uremic Toxins With Nocturnal Dialysis Versus Standard Dialysis
Status: COMPLETED
Conditions: Chronic Renal Failure
Interventions: PROCEDURE: Nocturnal dialysis|PROCEDURE: Standard dialysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Peptide Vaccinations to Treat Patients With Low-Risk Myeloid Cancers
Status: COMPLETED
Conditions: Myelodysplastic Syndrome (MDS)|Acute Myeloid Leukemia (AML)|Chronic Myeloid Leukemia (CML)
Interventions: BIOLOGICAL: WT1:126-134|BIOLOGICAL: PR1:169-177 Peptide|DRUG: GM-CSF (Sargramostim)|BIOLOGICAL: Montanide adjuvant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety of Labeled Dendritic Cell (DC) Vaccines and Feasibility of Tracking by Magnetic Resonance Imaging (MRI)
Status: COMPLETED
Conditions: Colorectal Neoplasms|Colorectal Cancer|Colorectal Carcinoma|Colorectal Tumors|Neoplasms, Colorectal
Interventions: BIOLOGICAL: DC Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized-controlled Study of a Cognitive-behavioral Intervention for Children With Functional Abdominal Pain
Status: COMPLETED
Conditions: Functional Abdominal Pain Syndrome|Abdominal Pain
Interventions: BEHAVIORAL: Intervention group|BEHAVIORAL: Active control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Methionine and Cysteine Restriction in Humans
Status: COMPLETED
Conditions: Overweight
Interventions: BEHAVIORAL: Low met/cys diet|BEHAVIORAL: Moderate met/cys diet|BEHAVIORAL: High met/cys diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Assessment of the New Automated Vitrification System "GAVI" for Early Cleaved Embryos Cryopreservation
Status: COMPLETED
Conditions: Fertility Disorders
Interventions: OTHER: reference technique|OTHER: vitrification technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Combination of Ranibizumab and Targeted Laser Photocoagulation
Status: RECRUITING
Conditions: Central Retinal Vein Occlusion With Macular Edema
Interventions: DRUG: Ranibizumab Injection|DEVICE: Laser photocoagulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Enoxaparin 20mg Versus 30mg Subcutaneously Once Daily in Elderly Patients With Impaired Renal Function
Status: COMPLETED
Conditions: Venous Thromboembolism|Renal Impairment
Interventions: DRUG: Enoxaparin 20Mg/0.2mL Prefilled Syringe|DRUG: Enoxaparin 60Mg/0.6Ml Inj Syringe 0.6Ml
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Dopamine in Acute Decompensated Heart Failure (DAD-HF) Trial
Status: UNKNOWN
Conditions: Acute Heart Failure
Interventions: DRUG: Furosemide|DRUG: low-dose dopamine + low-dose furosemide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Treatments for Homeless Youths
Status: COMPLETED
Conditions: Substance Abuse
Interventions: BEHAVIORAL: Community Reinforcement Approach (CRA) + HIV prevention|BEHAVIORAL: Case Management + HIV Prevention|BEHAVIORAL: Motivational Enhancement Therapy (MET) + HIV prevention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Validation of Radioisotope Guided Lymphadenectomy for Loco-regional Staging in Patients With Intermediate or High-risk Prostate Cancer
Status: COMPLETED
Conditions: Patient With Prostate Cancer
Interventions: PROCEDURE: standard lymphadenectomy|PROCEDURE: lymphadenectomy radio-isotope method
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Efficacy and Safety of Fondaparinux for the Prevention of Venous Blood Clots in Patients With a Plaster Cast or Other Type of Immobilization for a Below-knee Injury Not Needing Surgery
Status: COMPLETED
Conditions: Thrombosis, Venous
Interventions: DRUG: Fondaparinux sodium|DRUG: Nadroparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluating Qigong as a Clinical Intervention for Cancer Survivors' Fatigue
Status: UNKNOWN
Conditions: Fatigue
Interventions: OTHER: Qigong|OTHER: Complete Health Improvement Program (CHIP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pain After Laparoscopic Cholecystectomy With Bilateral Tranversus Abdominis Plane (TAP) Block Versus Local Anesthetic Infiltration
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: PROCEDURE: TAP Block|PROCEDURE: Local infiltration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Temsirolimus in Treating Patients With Cervical Cancer That Is Recurrent, Locally Advanced, Metastatic, or Cannot Be Removed By Surgery
Status: COMPLETED
Conditions: Cervical Adenocarcinoma|Cervical Adenosquamous Carcinoma|Cervical Squamous Cell Carcinoma|Recurrent Cervical Carcinoma|Stage IIIA Cervical Cancer|Stage IIIB Cervical Cancer|Stage IVA Cervical Cancer|Stage IVB Cervical Cancer
Interventions: DRUG: Temsirolimus|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Steroid Injection vs. BioDRestore for Patients With Knee OA
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: DEVICE: BioD Restore|DRUG: Kenalog
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Yoga for Chronic Low Back Pain and Its Mechanism of Action: Impact of Strength and Stretch (YoMA II)
Status: COMPLETED
Conditions: Chronic Low Back Pain
Interventions: BEHAVIORAL: Yoga|BEHAVIORAL: Self-Directed Mind-Body Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Alflutinib Mesylate Versus Gefitinib in Patients With Locally Advanced or Metastatic Non-small Cell Lung Cancer （FLAG）
Status: UNKNOWN
Conditions: Locally Advanced or Metastatic EGFR Sensitising Mutation Positive Non-small Cell Lung Cancer
Interventions: DRUG: Alflutinib Mesylate (AST2818) 80mg//40 mg+ placebo|DRUG: Placebo Gefitinib 250 mg|DRUG: Gefitinib 250 mg|DRUG: Placebo AST2818 80mg//40 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating Effectiveness and Adherence of Inclisiran Plus Standard of Care (SoC) Lipid-lowering Therapy Compared to SoC in ASCVD
Status: RECRUITING
Conditions: Primary Hypercholesterolemia|Mixed Dyslipidemia
Interventions: OTHER: Inclisiran
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Servo-n HFOV Study: Safety and Performance in Neonates and Infants
Status: RECRUITING
Conditions: Elective HFOV for Respiratory Failure in Neonates/Infants|Rescue HFOV in Neonates and/Infants With Refractory Respiratory Failure Under Conventional Therapy
Interventions: DEVICE: Servo-n HFOV modes
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: SYMPHONIE - A Comparison of Symbicort Single Inhaler and Conventional Best Practice for the Treatment of Persistent Asthma in Adolescents and Adults
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Budesonide/formoterol Turbuhaler
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Low Intensity Blood Flow Restriction on Clinical Outcomes in Women With Knee Osteoarthritis
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: OTHER: BFRT|OTHER: Routine Physical Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of High Intensity Laser on Muscle Quality and Pain in Those With Low Back Pain
Status: WITHDRAWN
Conditions: Low Back Pain
Interventions: DEVICE: CureWave High Intensity Laser|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective Evaluation of Limbal Relaxing Incision (LRI) in Conjunction With Phacoemulsification Surgery for Astigmatic Correction in Chinese Eyes
Status: UNKNOWN
Conditions: Corneal Astigmatism
Interventions: PROCEDURE: Limbal relaxing incision
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Efficacy of Dronabinol (Marinol) as Add-On Therapy for Patients on Opioids for Chronic Pain
Status: COMPLETED
Conditions: Chronic Pain
Interventions: DRUG: Marinol (dronabinol)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Online Exergaming-Integrated Physiotherapy for Parkinson's Disease
Status: NOT_YET_RECRUITING
Conditions: Parkinsonism in Diseases Classified Elsewhere
Interventions: OTHER: online exergaming-based physiotherapy programs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Efficacy and Safety of Ibrexafungerp in Patients With Fungal Diseases That Are Refractory to or Intolerant of Standard Antifungal Treatment
Status: COMPLETED
Conditions: Invasive Candidiasis|Mucocutaneous Candidiasis|Coccidioidomycosis|Histoplasmosis|Blastomycosis|Chronic Pulmonary Aspergillosis|Allergic Bronchopulmonary Aspergillosis|Invasive Pulmonary Aspergillosis|Recurrent Vulvovaginal Candidiasis|Other Emerging Fungi
Interventions: DRUG: Ibrexafungerp
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral Vancomycin Followed by Fecal Transplant Versus Tapering Oral Vancomycin
Status: TERMINATED
Conditions: Recurrent Clostridium Difficile Infection|Laboratory Confirmed Clostridium Difficile Infection
Interventions: DRUG: Vancomycin|BIOLOGICAL: Fecal Transplant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Neuro-dynamic Mobilization Techniques on Upper Limb Functions in Pronator Teres Syndrome
Status: COMPLETED
Conditions: Pronator Teres Syndrome
Interventions: OTHER: Upper limb Neuro-dynamics (Slider/ Tensioner Technique)|OTHER: Conventional Therapy for Upper limb
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of CLORazepate for the Treatment of MIGraine Attack in the Emergency Room
Status: TERMINATED
Conditions: Migraine|Migraine Without Aura|Migraine With Aura|Headache
Interventions: DRUG: Clorazepate Dipotassium|DRUG: Placebo|DRUG: Ketoprofen|DRUG: Metoclopramide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Savolitinib vs. Sunitinib in MET-driven PRCC.
Status: ACTIVE_NOT_RECRUITING
Conditions: Carcinoma|Carcinoma, Renal Cell|Kidney Neoplasms|Urologic Neoplasms|Kidney Diseases|Neoplasms by Site|Enzyme Inhibitors|Protein Kinase Inhibitors
Interventions: DRUG: Savolitinib|DRUG: Sunitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Evaluation of Microsurgery vs Conventional Surgical Technique of Gingival Depigmentation
Status: NOT_YET_RECRUITING
Conditions: Gingival Pigmentation|Melanosis
Interventions: PROCEDURE: Gingival depigmentation using microsurgery|PROCEDURE: Conventional surgical depigmentation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ultrasound Treatment on Wound Healing Time
Status: RECRUITING
Conditions: Burn Wound|2nd Degree Burn of the Skin
Interventions: DEVICE: Pulsed splenic ultrasound|DEVICE: Ultrasound probe (no energy applied)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Ascending Multiple Dose Study With VTP-43742 in Healthy Volunteers
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: Placebo|DRUG: VTP-43742
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Peripheral Electrical Stimulation With Focused Ultrasound on Motor Symptoms in Parkinson's Patients
Status: RECRUITING
Conditions: Parkinson Disease
Interventions: DEVICE: Real TUS|DEVICE: Real FES|DEVICE: Sham TUS|DEVICE: Sham FES
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Biolimus A9™ (BA9™) Drug Coated Balloon (DCB) Study
Status: UNKNOWN
Conditions: Coronary Artery Disease|In-Stent Restenosis
Interventions: DEVICE: Biolimus A9 Drug Coated Balloon|DEVICE: SeQuent Please Paclitaxel Drug Coated Balloon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study of Apixaban in Patients Receiving Hemodiafiltration
Status: COMPLETED
Conditions: Atrial Fibrillation|Hemodialysis Complication
Interventions: DRUG: Apixaban 2.5 milligram Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Temozolomide Chronotherapy for High Grade Glioma
Status: COMPLETED
Conditions: Glioma|Glioblastoma Multiforme
Interventions: DRUG: Temozolomide|OTHER: Functional Assessment of Cancer Therapy - Brain|OTHER: ActTrust Condor Instrument Watch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase III Trial of Niraparib Versus Physician's Choice in HER2 Negative, Germline BRCA Mutation-positive Breast Cancer Patients
Status: TERMINATED
Conditions: Neoplasms, Breast|Carcinoma of Breast|Human Epidermal Growth Factor 2 Negative Carcinoma of Breast|BRCA1 Gene Mutation|BRCA2 Gene Mutation|Ovarian Neoplasms
Interventions: DRUG: niraparib|DRUG: Physician's choice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clofarabine-Melphalan-Alemtuzumab Conditioning in Patients With Advanced Hematologic Malignancies
Status: COMPLETED
Conditions: Advanced Hematologic Malignancies|Leukemia|Preleukemia
Interventions: DRUG: Clofarabine|DRUG: Melphalan|DRUG: Campath|PROCEDURE: Stem Cell Transplant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Does Preconditioning Affects Other Organs in Patients Undergoing Open Heart Surgery ?
Status: COMPLETED
Conditions: Neutrophil Lymphocyte Ratio|Serum Createnine|Mechanical Ventilation
Interventions: PROCEDURE: ischemic preconditioning|DRUG: Pharmacologic preconditionig
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Discontinuation of Antibiotic Susceptibility Testing on Enterococcus Faecalis Positive Urine Cultures in Hospitalized Patients: an Impact on Antibiotic Prescriptions? (FaecaCible)
Status: COMPLETED
Conditions: Antibiotic Susceptibility Reporting
Interventions: OTHER: Stop performing an antibiotic susceptibility test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p