pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Comparison Between Single Shot Ultrasonographic Guided Fascia Iliaca Block and Quadratus Lumborum Block in Hip Arthralgia. Comparative Double Blind Study
Status: UNKNOWN
Conditions: Analgesia
Interventions: PROCEDURE: Sonar guided fascia iliaca|PROCEDURE: Sonar guided quadratus lumborum block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of rTMS to the Prefrontal Cortex in Alcohol Use Disorder
Status: RECRUITING
Conditions: Alcohol Use Disorder
Interventions: DEVICE: active rTMS|BEHAVIORAL: Inpatient admission|DEVICE: sham rTMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Fourteen-Week Placebo-Controlled Dose-Response Efficacy and Safety Study of NS 2330 in Early Parkinson's Disease Patients (Study for Proof of Concept in Early Parkinson's Disease of a Triple Reuptake Inhibitor, NS 2330 / SCEPTRE)
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: DRUG: NS 2330
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Preoperative Chemoradiotherapy With Raltitrexed for Intermediate or Locally Advanced Rectal Cancer in the Fit Elderly
Status: COMPLETED
Conditions: Rectal Neoplasms Malignant
Interventions: RADIATION: Preoperative radiation|DRUG: Raltitrexed|PROCEDURE: Pelvic surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Study of CAP-232 in Patients With Refractory Metastatic Renal Cell Carcinoma
Status: COMPLETED
Conditions: Carcinoma, Renal Cell
Interventions: DRUG: CAP-232
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare Mabthera (Rituximab), Fludarabine and Cyclophosphamide to Mabthera and Chlorambucil in Participants With Chronic Lymphocytic Leukemia and Unfavorable Somatic Status
Status: TERMINATED
Conditions: Lymphocytic Leukemia, Chronic
Interventions: DRUG: Chlorambucil|DRUG: Cyclophosphamide|DRUG: Fludarabine|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Once-Daily Oral VT-464 in Patients With Castration-Resistant Prostate Cancer
Status: COMPLETED
Conditions: Castration-resistant Prostate Cancer|CRPC
Interventions: DRUG: VT-464: given orally once daily in 28 day cycles
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cisplatin and Docetaxel With or Without Radiation Therapy in Treating Patients Who Are Undergoing Surgery for Newly Diagnosed Stage III Non-Small Cell Lung Cancer
Status: TERMINATED
Conditions: Lung Cancer
Interventions: BIOLOGICAL: filgrastim|BIOLOGICAL: pegfilgrastim|DRUG: cisplatin|DRUG: docetaxel|PROCEDURE: adjuvant therapy|PROCEDURE: conventional surgery|PROCEDURE: neoadjuvant therapy|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hydro-mechanical Defragmentation of Pulmonary Embolism
Status: COMPLETED
Conditions: Pulmonary Embolism
Interventions: PROCEDURE: catheter directed hydro-mechanical fragmentation of pulmonary embolism
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomised, Double-blind, Placebo-controlled Trial to Assess Safety, Tolerability and Pharmacokinetics of Liraglutide in Obese Adolescent Subjects Aged 12 to 17 Years
Status: COMPLETED
Conditions: Metabolism and Nutrition Disorder|Obesity
Interventions: DRUG: liraglutide|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Project I Test: Implementing HIV Testing in Opioid Treatment Programs
Status: RECRUITING
Conditions: HIV/AIDS|Hepatitis C|Substance Use Disorders|Opioid-use Disorder
Interventions: OTHER: Information Control|OTHER: HIV and HCV Testing Practice Coaching Intervention|OTHER: HIV Testing Practice Coaching Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study of Default Options in Advance Directives
Status: COMPLETED
Conditions: COPD|Severe or Very Severe Airflow Obstruction and/or Receiving or Eligible to Receive Long-term Oxygen Therapy|Idiopathic Pulmonary Fibrosis|Other Interstitial Lung Disease Without Curative Therapy|Congestive Heart Failure|NYHA Class IV or NYHA Class III Plus 1 Hospitalization in the Past Year|Malignancy|Any Stage 3B or 4 Solid Tumor
Interventions: OTHER: Comfort Default AD forms|OTHER: Life Extension Default AD forms|OTHER: Standard Default AD forms
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Double-Blind Placebo-Controlled Study Comparing the Combination of 15% SP-303 Gel With Acyclovir Versus Acyclovir Alone for the Treatment of Recurrent Herpes Simplex Virus (HSV) Infections in Subjects With Acquired Immunodeficiency Syndrome (AIDS)
Status: COMPLETED
Conditions: Herpes Simplex|HIV Infections
Interventions: DRUG: Crofelemer|DRUG: Acyclovir
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Three Times a Day BIAsp-70 Compared to Two Times a Day BIAsp-30 in Subjects With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: biphasic insulin aspart
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Preoperative Patient Education on Early Ambulation in Gynecological Surgery
Status: RECRUITING
Conditions: Gynecologic Nursing|Surgery|Nurse's Role
Interventions: BEHAVIORAL: Preoperative patient education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Impact of Neurophysiological Facilitation of Respiration in Preterm Neonates
Status: UNKNOWN
Conditions: Neonatal Respiratory Distress Syndrome
Interventions: OTHER: Neurophysiological Facilitation of Respiration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Multicenter Randomized 52 Week Treatment Double-blind, Triple Dummy Parallel Group Study to Assess the Efficacy and Safety of QMF149 Compared to Mometasone Furoate in Participants With Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Indacaterol acetate/Mometasone furoate|DRUG: Mometasone furoate|DRUG: Salmeterol xinafoate/fluticasone propionate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Localized Prostate Cancer With High Intensity Focused Ultrasound Using the Sonablate® 500 System in Canada
Status: UNKNOWN
Conditions: Prostate Cancer
Interventions: DEVICE: Sonablate 500 (SB-500)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Telbivudine Renoprotective Effect in Patients With the HBV-related Liver Cirrhosis: a Randomized Controlled Trial
Status: UNKNOWN
Conditions: HBV-related Liver Cirrhosis
Interventions: DRUG: Telbivudine|DRUG: Enecavir|DRUG: Adefovir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ladarixin With Sotorasib in Advanced NSCLC - Phase II
Status: WITHDRAWN
Conditions: Advanced Non-small Cell Lung Cancer With KRAS G12C Mutation
Interventions: DRUG: Sotorasib|DRUG: Ladarixin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety and Efficacy of SDP-4 in Subjects With Dry Eye Disease (DED)
Status: COMPLETED
Conditions: Dry Eye
Interventions: DRUG: SDP-4 Ophthalmic Solution (0.1%)|DRUG: SDP-4 Ophthalmic Solution (1.0%)|DRUG: SDP-4 Ophthalmic Solution (3.0%)|DRUG: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1, First Time in Human (FTIH) Study to Evaluate GSK3352589, a REarranged During Transfection (RET) Growth Factor Receptor Tyrosine Kinase Inhibitor, in Healthy Volunteers
Status: COMPLETED
Conditions: Irritable Bowel Syndrome
Interventions: DRUG: GSK3352589|DRUG: Matching Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: ROM Outcomes in Patients Undergoing a Primary TKA
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: OTHER: Patient will be shown a photograph of their knee at 2 weeks postop|OTHER: Patient will not be shown a photograph of their knee at 2 weeks postop
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: NeuroSuitUp: Neurorehabilitation Through Synergistic Man-machine Interfaces
Status: NOT_YET_RECRUITING
Conditions: Spinal Cord Injuries
Interventions: DEVICE: Brain-Computer Interface control of robotic arms with augmented reality|DEVICE: Serious game with augmented reality
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Endocrine Treatment Alone for Elderly Patients With Estrogen Receptor Positive Operable Breast Cancer and Low Recurrence Score
Status: RECRUITING
Conditions: Breast Cancer|Cancer of Breast|Breast Neoplasms|Cancer of the Breast
Interventions: BEHAVIORAL: FACT-B|DRUG: Goserelin|DRUG: Anastrozole|DRUG: Exemestane|DRUG: Fulvestrant|DRUG: Tamoxifen|OTHER: Archived tissue collection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Oncopanel Pilot (TOP) Study
Status: COMPLETED
Conditions: Colorectal Cancer Metastatic|Advanced Non-Small Cell Lung Carcinoma|Advanced Melanoma|Gastrointestinal Stromal Tumors|Patients With Diagnosed Malignancies Being Considered for Clinical Trials
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Perforator Artery Changes During Suprafascial Pre-expansion of the Perforator Flaps
Status: COMPLETED
Conditions: Scar|Contracture|Flap Disorder
Interventions: PROCEDURE: preexpanded perforator flap surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GR270773 In The Treatment Of Suspected Or Confirmed Gram-Negative Severe Sepsis In Adults
Status: COMPLETED
Conditions: Sepsis
Interventions: DRUG: Intravenous GR270773- Phospholipid Emulsion|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: The Effect of Pelvic Floor Muscle Training for Urinary Incontinence in Nepalese Women
Status: RECRUITING
Conditions: Urinary Incontinence
Interventions: OTHER: Education|OTHER: Education and PFMT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prehospital Risk Stratification in Acute Coronary Syndromes
Status: COMPLETED
Conditions: Acute Coronary Syndrome|Non-ST Elevation Myocardial Infarction (nSTEMI)
Interventions: DIAGNOSTIC_TEST: Ultrasound|DIAGNOSTIC_TEST: Troponin- T quick test
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Single Rotary File Pulpectomy in Primary Molars
Status: RECRUITING
Conditions: Pulpitis - Irreversible
Interventions: DEVICE: Fanta AF blue rotary files 20 taper 4|DEVICE: Fanta AF baby rotary files 20 , 25 , 30 taper 4
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Postprandial Glycemia in Apple Products
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Apple Juice1|DIETARY_SUPPLEMENT: Apple Juice2|DIETARY_SUPPLEMENT: Raw Apple
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Assessment of the Efficacy of the Aerodentis System
Status: COMPLETED
Conditions: Orthodontic Treatment|Tooth Crowding|Orthodontics
Interventions: DEVICE: Aerodentis system|DEVICE: Invisalign clear aligner system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Mindfulness-Based Cognitive Therapy Effect on Depression and C-Reactive Protein Levels After 8 Weeks of Treatment
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: BEHAVIORAL: Mindfulness-Based Cognitive Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized Double-Blind Placebo Controlled Trial to Determine the Status of Post Knee Chondroplasty Patients Administered Theramine Versus Placebo in Addition to Post Surgery Analgesics
Status: TERMINATED
Conditions: Knee Pain|Knee Chondroplasty
Interventions: DRUG: Theramine|DRUG: Theramine- like placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Experimental Medication BMS-986231 in Patients With Different Levels of Kidney Function
Status: COMPLETED
Conditions: Myocardial Failure|Cardiac Failure|Congestive Heart Failure|Kidney Failure|Renal Failure
Interventions: DRUG: BMS-986231
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sequential Tranylcypromine (TC), TC + Dextroamphetamine and TC + Triiodothyronine for Refractory Depression
Status: TERMINATED
Conditions: Major Depression
Interventions: DRUG: Tranylcypromine|DRUG: Dextroamphetamine|DRUG: Triiodothyronine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Evaluation of Hyperbaric Treatments for Children With Cerebral Palsy
Status: TERMINATED
Conditions: Cerebral Palsy|Cerebral Palsy, Spastic
Interventions: DEVICE: Hyperbaric Oxygen Treatment|DEVICE: Hyperbaric Air Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intervention Study to Evaluate a Probiotic in Mild Atopic Dermatitis Young Patients
Status: COMPLETED
Conditions: Dermatitis, Atopic
Interventions: DIETARY_SUPPLEMENT: Probiotic|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Pharmacokinetics and Pharmacodynamics Study of HL-032 in Healthy Male Volunteers
Status: COMPLETED
Conditions: Growth Hormone Deficiency
Interventions: DRUG: Somatropin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Pharmacokinetic Interaction Study Between Apatinib and Rosuvastatin or Metformin in Solid Tumor Subjects.
Status: COMPLETED
Conditions: Solid Tumor, Adult
Interventions: DRUG: Apatinib in arm1|DRUG: Rosuvastatin|DRUG: Apatinib in arm2|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility and Accuracy of a Novel Pleural Drain Gas Analyzer in Detecting Air Leaks
Status: NOT_YET_RECRUITING
Conditions: Air Leak From Lung|Pneumothorax
Interventions: DEVICE: Pleural gas analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effectivenes of Non-invasive Neuromodulation in Adult Women With Primary Dysmenorrhea, Through the TENS Stimulation at Different Times of Mentrual Cycle in Each Group
Status: RECRUITING
Conditions: Primary Dysmenorrhea
Interventions: DEVICE: Transcutaneous Electrical Nerve Stimulation (TENS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Influence of Different Tamponade Eyes on IOL-capsular Complex
Status: UNKNOWN
Conditions: Cataract|Vitreoretinal Abnormality
Interventions: PROCEDURE: phacovitrectomy surgery with silicone oil tamponade|PROCEDURE: phacovitrectomy surgery with gas tamponade|PROCEDURE: phacovitrectomy surgery with balanced saline solution tamponade|PROCEDURE: phacoemulsifacation surgery without vitrectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety, Tolerability and Drug Levels of BMS-986454 in Healthy Participants
Status: RECRUITING
Conditions: Healthy Participants
Interventions: DRUG: BMS-986454|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Internet-delivered Therapy for Alcohol Misuse: Factorial Trial of Assessment and Guidance
Status: COMPLETED
Conditions: Alcohol Misuse
Interventions: BEHAVIORAL: Assessment Interview|BEHAVIORAL: Guidance|BEHAVIORAL: ICBT for alcohol misuse
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Treatment With Insulin Sensitizer on Arterial Properties, Metabolic Parameters and Liver Function in Patients With Nonalcoholic Fatty Liver Disease
Status: COMPLETED
Conditions: Nonalcoholic Fatty Liver Disease
Interventions: DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose:
Clinical trial: Automated Setting of Individualized Sodium Technology
Status: COMPLETED
Conditions: End Stage Renal Disease (ESRD)
Interventions: DEVICE: Artis Haemodialysis Machine w/ ASIST Software - Isonatremic|DEVICE: Artis Haemodialysis Machine w/ ASIST Software - Isotonic|DEVICE: Artis Haemodialysis Machine w/o ASIST Software
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial to Evaluate Plasmodium Falciparum 7G8 and NF54 Challenge Strains (PfSPZ) in a Head-to-head Comparative Study - (ECG-CHMI)
Status: WITHDRAWN
Conditions: Plasmodium Falciparum
Interventions: DRUG: atovaquone-proguanil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: PET Imaging of Cannabinoid CB1 Receptors Using [18F]FMPEP-d2
Status: COMPLETED
Conditions: CB1|Cannabinoid|PET|Brain Imaging
Interventions: DRUG: [18F]FMPEP-d2
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Retroclavicular Versus Coracoid Approach for Infraclavicular Brachial Plexus Block
Status: COMPLETED
Conditions: Disorder of Upper Extremity
Interventions: OTHER: coracoid approach|OTHER: retroclavicular approach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Prospective Evaluation of 68Ga-PSMA PET-CT for Recurrence Detection of Prostate Cancer and Its Impact on Patient Management
Status: WITHDRAWN
Conditions: Prostate Cancers
Interventions: DRUG: 68Ga-(HBED-CC)-PSMA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Multicenter Phase 2 Study of Envafolimab in Biliary Tract Cancers
Status: NOT_YET_RECRUITING
Conditions: Biliary Tract Neoplasms
Interventions: DRUG: Envafolimab plus Gemcitabine&Cisplatin|DRUG: Gemcitabine&Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Percutaneous Transforaminal Endoscopic Discectomy vs Microendoscopic Discectomy for Treatment of Lumbar Disc Herniation
Status: UNKNOWN
Conditions: Lumbar Herniated Disc
Interventions: PROCEDURE: Percutaneous transforaminal endoscopic discectomy (PTED)|PROCEDURE: Microendoscopic discectomy (MED)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Standard Compression Therapy With/Without Application of Skin Allograft (Theraskin) for Venous Leg Ulcer Treatment
Status: UNKNOWN
Conditions: Chronic Venous Hypertension With Ulcer
Interventions: PROCEDURE: Standard Multi-layered Compression dressing|PROCEDURE: Standard Multi-layered Compression dressing with a cryopreserved skin allograft (TheraSkin)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Non-Pharmacologic Interventions to Relief Pain in Healthy Newborns Submitted to Vaccination to Hepatitis B
Status: COMPLETED
Conditions: Pain|Analgesia
Interventions: PROCEDURE: Water 2mL PO 2 minutes prior to intra-muscular injection|PROCEDURE: skin-to-skin contact|PROCEDURE: Glucose 25% 2 mL PO 2 minutes prior to injection|PROCEDURE: neonates will receive skin-to-skin contact beginning 2 minutes after the intra-muscular injection and stopping 2 minutes afterwards.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of WB-EMS Versus HIT-Resistance Training (RT)
Status: TERMINATED
Conditions: Healthy|Sedentary|Untrained
Interventions: OTHER: Whole Body Electromyostimulation|OTHER: High Intensity Resistance Exercise Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mucociliary Clearance Time in Chronic Rhinosinusitis (CRS) Patients After Sinus Surgery
Status: COMPLETED
Conditions: Chronic Rhinosinusitis
Interventions: OTHER: 1% Johnson's Baby Shampoo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study for the Evaluation of "MitoScore" Marker in the Diagnosis of Embryo Viability in Euploids Embryos
Status: UNKNOWN
Conditions: Infertility
Interventions: OTHER: Transfer according to morphological criteria|OTHER: Transfer according to the MitoScore results
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: EXOPULSE Mollii Suit & Cerebral Palsy
Status: RECRUITING
Conditions: Cerebral Palsy
Interventions: DEVICE: EXOPULSE MOLLII SUIT (active)|DEVICE: EXOPULSE MOLLII SUIT (sham)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Motexafin Gadolinium for the Treatment of Renal Cell (Kidney) Cancer
Status: COMPLETED
Conditions: Carcinoma, Renal Cell|Urogenital Neoplasms|Urologic Neoplasms|Kidney Neoplasms
Interventions: DRUG: motexafin gadolinium
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 3 Lot to Lot Consistency Study of Live Oral Cholera Vaccine, PXVX0200 in Healthy Adults
Status: COMPLETED
Conditions: Cholera
Interventions: BIOLOGICAL: PXVX0200 Lot A|BIOLOGICAL: PXVX0200 Lot B|BIOLOGICAL: PXVX0200 Lot C|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Kidney Damage in Patients With Normal eGFR
Status: COMPLETED
Conditions: Coronary Artery Stenosis
Interventions: DRUG: Non ionic contrast media comparator|DRUG: Non ionic contrast media comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effect of Early Mobilization and Fluid Consumption on Bowel Movements After Cholecystectomy
Status: COMPLETED
Conditions: Cholelithiases|Nursing Caries|Perioperative Complication|Bowel Ileus
Interventions: OTHER: Early mobilization and tea consumption|OTHER: Early mobilization and coffee consumption|OTHER: Early mobilization and warm water consumption|OTHER: Ongoing treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: ASP (PPI_H2RA) Study-H2RA Versus PPI for the Prevention of Recurrent UGIB in High-risk Users of Low-dose ASA
Status: COMPLETED
Conditions: Upper Gastrointestinal Bleeding
Interventions: DRUG: Rabeprazole|DRUG: Famotidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial Of Irinotecan In Combination With Three Methods Of Administration Of Fluoropyrimidine.
Status: COMPLETED
Conditions: Colorectal Neoplasms
Interventions: DRUG: Modified Bolus 5-FU/LV with Irinotecan|DRUG: FOLFIRI + bevacizumab|DRUG: miFL + bevacizumab|DRUG: Infusional 5-FU/LV with Irinotecan|DRUG: Oral Capecitabine with Irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vestibular Implantation to Treat Adult-Onset Bilateral Vestibular Hypofunction
Status: RECRUITING
Conditions: Other Disorders of Vestibular Function, Bilateral|Bilateral Vestibular Deficiency (BVD)|Gentamicin Ototoxicity|Labyrinth Diseases|Vestibular Diseases|Sensation Disorders|Bilateral Vestibular Hypofunction|Bilateral Vestibulopathy|Aminoglycoside Ototoxicity
Interventions: DEVICE: Labyrinth Devices MVI™ Multichannel Vestibular Implant System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Busulfan Pharmacokinetic Analysis and GST Polymorphism in Adults Undergoing Hematological Stem Cell Transplantation
Status: WITHDRAWN
Conditions: Busulfan Pharmacokinetic Analysis|GST Genetic Polymorphism
Interventions: DRUG: Hematological Stem Cell Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigation of the Efficacy of Zesteem in Accelerating Early Wound Healing
Status: COMPLETED
Conditions: Cicatrix|Wound-healing
Interventions: DRUG: Zesteem|DRUG: Zesteem|DRUG: Zesteem|DRUG: Zesteem|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Pain Education Elderly Subacromial Pain
Status: UNKNOWN
Conditions: Shoulder Pain
Interventions: OTHER: Education in pain, Manual Therapy and Exercises|OTHER: Manual Therapy and Exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Safety and Tolerability of SOBI003 in Pediatric MPS IIIA Patients
Status: COMPLETED
Conditions: Sanfilippo Syndrome Type A (MPS IIIA)
Interventions: DRUG: SOBI003
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hepatic Enzymes, Psychological Measures, and Sexual Dysfunction Responses to Aerobic Exercise in Hepatitis-C Men
Status: RECRUITING
Conditions: Hepatitis C|Erectile Dysfunction
Interventions: BEHAVIORAL: exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Antioxidation Medication for Noise-induced Hearing Loss
Status: COMPLETED
Conditions: Hearing Loss
Interventions: DRUG: N-acetylcysteine (NAC)|DRUG: glucose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effectiveness of Applying Multimedia on Self-Care and Quality of Life in Patient With Enterostomy
Status: COMPLETED
Conditions: Multimedia Learning Education|Self-care|Quality of Life|Enterostomy
Interventions: OTHER: multimedia education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Surgical Resection Lowers Oxidative Stress Markers in Patients With Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer|Colon Rectal Resection|Oxidative Stress
Interventions: PROCEDURE: Surgery for colorectal cancer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose:
Clinical trial: A Study of Pregabalin (Lyrica) Augmentation in Serotonin Reuptake Inhibitor-Refractory Obsessive Compulsive Disorder
Status: COMPLETED
Conditions: Obsessive-Compulsive Disorder
Interventions: DRUG: pregabalin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Iohexol Clearance in Critically Ill Patients With Augmented Renal Creatinine Clearance
Status: RECRUITING
Conditions: Augmented Renal Clearance|Critically Ill
Interventions: DRUG: Iohexol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Losartan Potassium/Hydrochlorothiazide 100/25 mg Tablets in Healthy Subjects Under Fasting Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Losartan potassium/Hydrochlorothiazide|DRUG: Hyzaar®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: The Effects of an Acute Bout of Exercise on Alcohol and Cocaine Craving - an fNIRS Study
Status: UNKNOWN
Conditions: Substance Use Disorders
Interventions: OTHER: Moderate exercise|OTHER: Intense exercise|OTHER: Reading
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cytisine Versus Varenicline for Smoking Cessation
Status: COMPLETED
Conditions: Smoking Cessation
Interventions: DRUG: Cytisine|BEHAVIORAL: Behavioural support|DRUG: Varenicline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Documentation of Efficacy of Intralymphatic Allergen Immunotherapy
Status: UNKNOWN
Conditions: Allergic Rhinitis Due to Grass Pollen|Allergic Conjunctivitis of Both Eyes|Allergic Asthma
Interventions: DRUG: Grass pollen extract - Alutard Phleum pratense, ALK
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CD36 in Nutrient Delivery and Its Dysfunction
Status: COMPLETED
Conditions: Insulin Resistance|Endothelial Dysfunction
Interventions: DRUG: Sildenafil Citrate in G allele carrier|DRUG: Sildenafil Citrate in non G allele carrier
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Prevention and Treatment of Pyrrolitinib-associated Diarrhea
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: DRUG: Loperamide|DRUG: Loperamide and golden bifid|DRUG: Loperamide and montmorillonite powder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Vitamin D Deficiency: Bone Loss and Vascular Dysfunction
Status: COMPLETED
Conditions: Postmenopausal Women
Interventions: PROCEDURE: 10 vit. D deficient subjects take vit. D for 3 months.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pre-oxygenation With Real Time End-tidal Oxygen Measurements Versus Single Breath Measurements
Status: COMPLETED
Conditions: Rapid Sequence Intubation
Interventions: DEVICE: Non-rebreather mask (NRBM)|DEVICE: Non-invasive ventilator mask (NIV)|DEVICE: Nasal cannula EtO2 sensor|DRUG: Oxygen (NRBM)|DRUG: Oxygen (NIV)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Intervention Targeting Medication Adherence and Methamphetamine Use in HIV Positive Men (ACE)
Status: COMPLETED
Conditions: HIV Medication Adherence|Methamphetamine Use|Sexual Risk|Poly-substance Use|HIV Infections
Interventions: BEHAVIORAL: Motivational Interviewing + Cognitive Behavioral Skills Training|BEHAVIORAL: Education Attention Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Analgesic Effect and Plasma Concentration of Epidural Versus Intravenous Fentanyl
Status: COMPLETED
Conditions: Fentanyl Analgesia
Interventions: DRUG: Fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Improving Value of Care for Patients With Severe Stasis Dermatitis
Status: COMPLETED
Conditions: Stasis Dermatitis
Interventions: OTHER: Order set|OTHER: Motivational Interviewing training for home health aides|OTHER: Tools & Education
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Effect of an Oral Supplement,TK3 (Tryptophan and Thiamine) on the Quality of Life and Chemotherapy Tolerance in Cancer Patients With Advanced Disease.
Status: UNKNOWN
Conditions: Cancer|Quality of Life|Chemotherapy Effect|Tryptophan|Thiamine
Interventions: DRUG: TK3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Prophylaxis Trial of Posaconazole Versus Standard Azole Therapy for Neutropenic Patients (Study P01899)
Status: COMPLETED
Conditions: Leukemia, Myelocytic, Acute|Myelodysplastic Syndromes|Neutropenia
Interventions: DRUG: Posaconazole oral suspension
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Phase I Trial of SIM1811-03 in Subjects With Advanced Tumors
Status: RECRUITING
Conditions: Advanced Solid Tumor|Cutaneous T Cell Lymphoma
Interventions: DRUG: SIM1811-03 or in combination with Sintilimab injectiont
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of an Ad26.RSV.PreF-based Regimen at the End of Shelf-life in Adults Aged 60 to 75 Years
Status: COMPLETED
Conditions: Respiratory Syncytial Virus Prevention
Interventions: BIOLOGICAL: Ad26.RSV.PreF-based Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Polyethylene-glycol Assisted Nerve Repair in Phalloplasty
Status: ENROLLING_BY_INVITATION
Conditions: Gender Dysphoria
Interventions: DRUG: Polyethylene Glycol 3350
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Feasibility of imILT Locally Advanced Pancreatic Cancer (LAPC)
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: PROCEDURE: immunostimulating Interstitial Laser Thermotherapy|DEVICE: Laser
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sorafenib, Cisplatin, and Etoposide in Treating Patients With Extensive-Stage Small Cell Lung Cancer
Status: TERMINATED
Conditions: Lung Cancer
Interventions: DRUG: cisplatin|DRUG: etoposide|DRUG: sorafenib tosylate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study of the ACRYSOF® IQ Extended Depth of Focus Intraocular Lens (IOL)
Status: COMPLETED
Conditions: Cataract
Interventions: DEVICE: ACRYSOF® IQ Extended Depth of Focus IOL|DEVICE: ACRYSOF® IQ Monofocal IOL|PROCEDURE: Cataract surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I Trial HIPEC With Nal-irinotecan
Status: COMPLETED
Conditions: Peritoneal Cancer|Pseudomyxoma Peritonei|Mucinous Adenocarcinoma|Mucinous Tumor|Colorectal Cancer|Gastric Cancer|Primary Peritoneal Carcinoma|Mesothelioma
Interventions: DRUG: nanoliposomal irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study of Efinopegdutide in People With Compensated Cirrhosis Due to Steatohepatitis (MK-6024-017)
Status: RECRUITING
Conditions: Non-alcoholic Fatty Liver Disease|Nonalcoholic Steatohepatitis|NAFLD|Metabolic Dysfunction-associated Steatotic Liver Disease|Metabolic Dysfunction-associated Steatohepatitis
Interventions: COMBINATION_PRODUCT: Efinopegdutide|COMBINATION_PRODUCT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Rituximab for Anti-cytokine Autoantibody-Associated Diseases
Status: COMPLETED
Conditions: Pulmonary Alveolar Proteinosis (PAP)|Severe Mucocutaneous Candidiasis
Interventions: DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact Evaluation of Benazir Nashonuma Program (BNP) on Stunting Among Under-five Children
Status: RECRUITING
Conditions: Stunting|Wasting|Anemia|Nutrient Deficiency
Interventions: COMBINATION_PRODUCT: Benazir Nashonuma Program (BNP)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Treatment of Severe Fear of Childbirth With CBT, Comparison of ICBT With Traditional Live Therapy
Status: COMPLETED
Conditions: Tocophobia
Interventions: BEHAVIORAL: Traditional Cognitive behavioural therapy|BEHAVIORAL: Internet based Cognitive behavioural therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multidisciplinary Approach to Novel Therapies in Cardiology Oncology Research
Status: UNKNOWN
Conditions: Breast Cancer|Heart Failure
Interventions: DRUG: perindopril OR bisoprolol OR placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: An Extension Long-Term Study of RoActemra/Actemra (Tocilizumab) in Patients With Polyarticular Juvenile Idiopathic Arthritis Who Completed The WA19977 Study
Status: COMPLETED
Conditions: Juvenile Idiopathic Arthritis
Interventions: DRUG: tocilizumab [RoActemra/Actemra]
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Trial of Foscenvivint in Liver Cirrhosis Patients Caused by HIV/HCV Co-infection With Hemophilia (OP-724-H201)
Status: RECRUITING
Conditions: Liver Cirrhosis
Interventions: DRUG: Foscenvivint
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Fiasp® (Fast Acting Insulin Aspart) in 670G Hybrid Closed-Loop Therapy
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: DRUG: Fiasp|DRUG: Novolog
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Efficacy of ABT-199 in Subjects With Relapsed/Refractory or Previously Untreated Chronic Lymphocytic Leukemia With the 17p Deletion
Status: COMPLETED
Conditions: Chronic Lymphocytic Leukemia|17p Deletion|Cancer of the Blood and Bone Marrow
Interventions: DRUG: ABT-199 (Main Cohort)|DRUG: ABT-199 (Safety Expansion Cohort)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multicenter Phase I/II Clinical Trial to Evaluate Safety of Mesenchymal Stem Cell in Patients With Amyotrophic Sclerosis Lateral
Status: COMPLETED
Conditions: Amyotrophic Lateral Sclerosis
Interventions: OTHER: Intravenous administration of placebo|DRUG: Intravenous administration of 1 million of MSC|DRUG: Intravenous administration of 2 million of MSC|DRUG: Intravenous administration of 4 million of MSC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clomiphene Citrate for the Treatment of Low Testosterone Associated With Chronic Opioid Pain Medication Administration
Status: COMPLETED
Conditions: Hypogonadism|Opioid-Related Disorders|Male Infertility
Interventions: DRUG: Clomiphene citrate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Efficacy, Tolerability, and Pharmacokinetics of MYMD1 for Chronic Inflammation and Sarcopenia/Frailty
Status: COMPLETED
Conditions: Sarcopenia|Frailty|Aging
Interventions: DRUG: MYMD-1 600MG|DRUG: MYMD-1 750mg|DRUG: MYMD-1 900mg|DRUG: MYMD-1 1050mg|DRUG: placebo 600mg|DRUG: placebo 750mg|DRUG: placebo 900mg|DRUG: placebo 1050mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Pioglitazone in Type 2 Diabetes Mellitus and Coronary Heart Disease
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus|Cardiovascular Disease
Interventions: DRUG: pioglitazone|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Effect of Indinavir Plus Two Other Anti-HIV Drugs on Blood Clotting in HIV-Positive Males With Hemophilia
Status: COMPLETED
Conditions: HIV Infections|Hemophilia A
Interventions: DRUG: Indinavir sulfate|DRUG: Lamivudine|DRUG: Stavudine|DRUG: Zidovudine|DRUG: Zalcitabine|DRUG: Didanosine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Relationship Between Alterations in the GI Microbiome and GI Inflammation on Symptom Burden in Women With Breast Cancer Receiving Chemotherapy
Status: RECRUITING
Conditions: Anatomic Stage I Breast Cancer AJCC v8|Anatomic Stage II Breast Cancer AJCC v8|Anatomic Stage III Breast Cancer AJCC v8
Interventions: OTHER: Non-Interventional Study
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Investigational Therapeutics for the Treatment of People With Ebola Virus Disease
Status: COMPLETED
Conditions: Ebola Virus
Interventions: DRUG: ZMapp|DRUG: Remdesivir|DRUG: MAb114|DRUG: REGN-EB3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: AVACEN Hand Heating on Fasting Blood Glucose
Status: COMPLETED
Conditions: Hyperglycemia|Hypertension
Interventions: DEVICE: AVACEN 100|DEVICE: AVACEN 100 Heat Only|DEVICE: AVACEN Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Motor Imagery on Children With DMD on Gait and Balance Functions
Status: RECRUITING
Conditions: Duchenne Muscular Dystrophy
Interventions: OTHER: Physiotherapy and Rehabilitation Program|OTHER: Additional Motor Imagery Training to Physiotherapy and Rehabilitation Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparative Efficacy of Standard vs. Adapted CBT-I for Adolescents With Insomnia : The DREAM-IT Study
Status: NOT_YET_RECRUITING
Conditions: Insomnia
Interventions: BEHAVIORAL: Cognitive Behavioral Therapy for Insomnia (CBT-I)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT