pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: An Investigational Study Drug, Palbociclib (PD-0332991), Is Being Studied In Patients With Mantle Cell Lymphoma. Patients Must Have Received Prior Treatment(s) For Mantle Cell Lymphoma.
Status: COMPLETED
Conditions: Lymphoma, Mantle-Cell
Interventions: DRUG: PD-0332991
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparaison Between Digital and Drug Induced Sedation in Veinous Access Device Implantation
Status: COMPLETED
Conditions: Oncology
Interventions: DEVICE: Sedakit (R) using hypnosis induced by the virtual reality device|DRUG: drug intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 24-Hour Glycemia: Rosiglitazone Versus Glimepiride In Type 2 Diabetes
Status: COMPLETED
Conditions: Non-Insulin-Dependent Diabetes Mellitus
Interventions: DRUG: rosiglitazone-metformin fixed dose combination|DRUG: metformin + glimepiride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PROTECT: On-line Adaptive Proton Therapy for Cervical Cancer
Status: RECRUITING
Conditions: Uterine Cervical Neoplasms|Locally Advanced Cervical Carcinoma
Interventions: RADIATION: External beam radiation therapy: IMRT/VMAT|RADIATION: External beam radiation therapy: IMPT|DRUG: Cisplatin|RADIATION: Brachytherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Phenotyping and Characterization of Neural Networks and Cognitive Processes Involved in Mental Retardation X-linked
Status: UNKNOWN
Conditions: X-linked Mental Retardation
Interventions: BEHAVIORAL: Neuropsychological, cognitive and behavioral assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Dutasteride After Failure of Finasteride In the Management of Symptomatic Prostatic Enlargement/Hypertrophy (BPE/H)
Status: COMPLETED
Conditions: Benign Prostatic Hypertrophy
Interventions: DRUG: Dutasteride
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Food Study to Evaluate the Effect of KB174 on the Gut Microbiome in Subjects With Well-compensated Cirrhosis
Status: COMPLETED
Conditions: Early Cirrhosis
Interventions: OTHER: KB174|OTHER: Maltodextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect of Maximal Exercise on MMP9 and TIMP1 and The Role of MMP9 -1562 C/T and TIMP1 372 T/C Polymorphisms
Status: COMPLETED
Conditions: MMP9|TIMP1|MMP9 -1562 C/T|TIMP1 372 T/C
Interventions: OTHER: Yo-Yo Intermittent Recovery Test Level 1
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect of Lower Urinary Tract Electrical Stimulation on Renal Urine Production (Diuresis)
Status: SUSPENDED
Conditions: Diuresis Under Eletrical Stimulation
Interventions: OTHER: electrical stimulation (non painful) of the lower urinary tract to determine the current perception threshold and record sensory evoked potentials
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: |Primary Purpose: BASIC_SCIENCE
Clinical trial: TRAIL Study: Feasibility and Pilot
Status: NOT_YET_RECRUITING
Conditions: Thyroid Nodule|Thyroid Neoplasms|Thyroid Cancer
Interventions: PROCEDURE: Biopsy|PROCEDURE: Active Monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Antecedent Hypoglycaemia on β2-adrenergic Sensitivity
Status: COMPLETED
Conditions: Diabetes|Hypoglycemia Unawareness
Interventions: PROCEDURE: Hypoglycemia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of the Pharmacokinetics and Immunologic Effects of Lipoic Acid in Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DRUG: oral lipoic acid (LA)|DRUG: lipoic acid (LA) with fish oil and LA without fish oil|DRUG: R lipoic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Scapular Strength Exercise for Patients With Lateral Epicondylalgia
Status: UNKNOWN
Conditions: Lateral Epicondylitis
Interventions: BEHAVIORAL: Scapular program|BEHAVIORAL: Conventional program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Open-Label, Multicenter, Phase I Study to Evaluate the Safety, Pharmacokinetics and Preliminary Efficacy of YY201 in Patients With Advanced Solid Tumors and Hematological Malignancies
Status: RECRUITING
Conditions: Advanced Solid Tumor|Hematological Malignancy
Interventions: DRUG: YY201
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fish Oil Supplementation to Pregnant Women in China
Status: COMPLETED
Conditions: Premature Birth
Interventions: DIETARY_SUPPLEMENT: High dose fish oil|DIETARY_SUPPLEMENT: Low dose fish oil|DIETARY_SUPPLEMENT: Olive oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: AutoMatic disPERsion Tagging Function Preliminary Evaluation
Status: COMPLETED
Conditions: Atrial Fibrillation|Atrial Tachycardia|Atrial Arrhythmia
Interventions: DEVICE: VX1+ dispersion mapping
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Dose-Finding Study of Cabozantinib (XL184) in Japanese Subjects With Advanced Cancer
Status: COMPLETED
Conditions: Solid Tumors|Cancer|NSCLC
Interventions: DRUG: cabozantinib capsules|DRUG: cabozantinib tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of SGLT-2 Inhibitor Dapagliflozin on Glycemic Variability in Patients With Diabetes Mellitus Type 2
Status: UNKNOWN
Conditions: Diabetes Mellitus|Hypoglycemic Episodes
Interventions: DRUG: Metformin|DRUG: Dapagliflozin|DRUG: Metformin up-titration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Video Telehealth Pulmonary Rehabilitation to Reduce Hospital Readmission in Chronic Obstructive Pulmonary Disease
Status: RECRUITING
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: BEHAVIORAL: Video Telehealth Pulmonary Rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: First Report of a New Exoskeleton in Incomplete Spinal Cord Injury
Status: COMPLETED
Conditions: Spinal Cord Injuries|Walking, Difficulty
Interventions: DEVICE: Exoskeletal robotic therapy for walking.|OTHER: Conventional exercise therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stem Cell Mobilization by G-CSF to Treat Severe Peripheral Artery Disease
Status: COMPLETED
Conditions: Peripheral Vascular Diseases
Interventions: DRUG: G-CSF|DRUG: Placebo|DRUG: Aspirin|DRUG: Clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cooling Leg and Foot Ulcer Skin Post Healing to Prevent Ulcer Recurrence
Status: COMPLETED
Conditions: Venous Hypertension Ulcers|Venous Stasis Ulcer|Venous Ulcer|Venous Insufficiency|Leg Ulcer|Foot Ulcer|Varicose Ulcer|Diabetic Foot
Interventions: DEVICE: Cooling gel pack|DEVICE: Cooling cotton pack
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Efficacy and Safety of Rimonabant 20mg/Day Versus Placebo in Smoking Cessation
Status: COMPLETED
Conditions: Smoking Cessation
Interventions: DRUG: rimonabant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Safety, Pharmacokinetics and Pharmacodynamics of UCB4940 in Patients With Psoriasis
Status: COMPLETED
Conditions: Mild to Moderate Psoriasis
Interventions: DRUG: UCB4940|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Subcutaneous Versus Intravenous MabThera/Rituxan (Rituximab) in Combination With CHOP Chemotherapy in Patients With Previously Untreated CD20-Positive Diffuse Large B-Cell Lymphoma
Status: COMPLETED
Conditions: Lymphoma, Large B-Cell, Diffuse
Interventions: DRUG: CHOP|DRUG: rituximab [MabThera/Rituxan]|DRUG: rituximab [MabThera/Rituxan]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Integration of Chronic Disease Rehabilitation Services Into Primary Care
Status: COMPLETED
Conditions: Cardiovascular Disease|Heart Failure|Chronic Obstructive Pulmonary Disease|Asthma|Diabetes
Interventions: BEHAVIORAL: Support, management, educational, counselling, follow-up
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Contralaterally Controlled FES of Arm & Hand for Subacute Stroke Rehabilitation
Status: COMPLETED
Conditions: Stroke|Hemiparesis|Hemiplegia
Interventions: DEVICE: Electrical Stimulator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: EphA2 siRNA in Treating Patients With Advanced or Recurrent Solid Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Malignant Solid Neoplasm
Interventions: DRUG: EphA2-targeting DOPC-encapsulated siRNA|OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacological Study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ASSESSMENT OF PAIN USING A PAIN DIAGNOSTIC SYSTEM THAT MEASURS FACIAL MOVEMENT USING
Status: RECRUITING
Conditions: Nursing|Pain Assessment|Critical Care|Technology|Facial Recognition
Interventions: BEHAVIORAL: Number of participants with treatment-related adverse events as assessed by CTCAE v4.0
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Dose Systemic Lidocaine Improve the Quality of Recovery After Colorectal Endoscopic Submucosal Dissection
Status: COMPLETED
Conditions: Postoperative Recovery
Interventions: DRUG: lidocaine|DRUG: 0.9% saline|DRUG: Propofol|DRUG: Sufentanil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: WJMSCs Anti-inflammatory Therapy in Coronary Artery Disease
Status: UNKNOWN
Conditions: Coronary Artery Disease
Interventions: BIOLOGICAL: Intravenous infusion human umbilical Wharton's jelly-derived mesenchymal stem Cell or placebo PBS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Pharmacokinetics Study to Investigate the Effect of Ketoconazole on Vemurafenib in Patients With BRAFV600 Mutation-Positive Metastatic Melanoma
Status: WITHDRAWN
Conditions: Malignant Melanoma, Neoplasms
Interventions: DRUG: ketoconazole|DRUG: vemurafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Induction Therapy Including 131 I-MIBG and Chemotherapy in Treating Patients With Newly Diagnosed High-Risk Neuroblastoma Undergoing Stem Cell Transplant, Radiation Therapy, and Maintenance Therapy With Isotretinoin
Status: ACTIVE_NOT_RECRUITING
Conditions: Ganglioneuroblastoma|Localized Resectable Neuroblastoma|Localized Unresectable Neuroblastoma|Regional Neuroblastoma|Stage 4 Neuroblastoma|Stage 4S Neuroblastoma
Interventions: RADIATION: 3-Dimensional Conformal Radiation Therapy|PROCEDURE: Autologous Hematopoietic Stem Cell Transplantation|DRUG: Busulfan|DRUG: Cisplatin|DRUG: Cyclophosphamide|DRUG: Doxorubicin Hydrochloride|DRUG: Etoposide Phosphate|RADIATION: External Beam Radiation Therapy|PROCEDURE: In Vitro-Treated Peripheral Blood Stem Cell Transplantation|RADIATION: Intensity-Modulated Radiation Therapy|RADIATION: Iobenguane I-131|DRUG: Isotretinoin|OTHER: Laboratory Biomarker Analysis|DRUG: Melphalan|OTHER: Pharmacological Study|OTHER: Questionnaire Administration|PROCEDURE: Therapeutic Conventional Surgery|DRUG: Topotecan Hydrochloride|DRUG: Vincristine Sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of AB023 (Xisomab 3G3) in End Stage Renal Disease Patients on Chronic Hemodialysis
Status: COMPLETED
Conditions: End Stage Renal Disease|Thrombosis
Interventions: DRUG: AB023- Dose 1|DRUG: AB023-Dose 2|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Point of Care 3D Ultrasound for Various Applications: A Pilot Study
Status: COMPLETED
Conditions: Appendicitis|Evidence of Cholecystectomy|Gallstones|Pregnancy, Ectopic|Aortic Aneurysm|Kidney Stones|Intrauterine Pregnancy|Diverticulitis|Abdominal Injuries|Tumors|Pancreatitis|Digestive System Diseases|Gastrointestinal Diseases|Intraabdominal Infections|Intestinal Diseases|Pregnancy|Vascular Disease|Uterine Fibroids|Ovarian Cysts|Uterine Abnominalies|Bladder Abnominalies|Testicular Abnominalies|Polyps
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Low-level Laser Therapy on Exercise-induced Muscle Damage
Status: COMPLETED
Conditions: Muscle Damage
Interventions: DEVICE: LLLT before muscle damage|DEVICE: Placebo LLLT before muscle damage|DEVICE: LLLT after muscle damage|DEVICE: Placebo LLLT after muscle damage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Botulinum Toxin A in Direct Eyebrow Lift Scar
Status: RECRUITING
Conditions: Skin Scarring|Eyebrow Ptosis
Interventions: DRUG: Botulinum toxin type A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial to Support Caregivers of Patients With Dementia in Italy: the UP-TECH Project
Status: COMPLETED
Conditions: Alzheimer Disease
Interventions: OTHER: Case Manager|OTHER: Assistive Technologies|OTHER: light support|OTHER: 3 preventive home visits by a nurse
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Genomic Biomarker-guided Neoadjuvant Therapy for Prostate Cancer (SEGNO)
Status: RECRUITING
Conditions: Locally Advanced Prostate Cancer|Oligometastatic Prostate Cancer
Interventions: DRUG: Rezvilutamide|DRUG: Goserelin Microspheres for Injection|DRUG: Docetaxel|DRUG: Pamiparib|DRUG: Cisplatin|DRUG: Tislelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose Escalation of Cisplatin Hyperthermic Intraperitoneal Chemotherapy After Surgery in Patients With Unresectable Stage IIIC Ovarian, Tube or Peritoneal Primary Adenocarcinoma
Status: COMPLETED
Conditions: Ovarian Adenocarcinoma|Fallopian Tube Adenocarcinoma|Primary Peritoneal Carcinoma
Interventions: DRUG: Cisplatin|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Outpatient Ketamine Infusion on Chronic Neuropathic Pain and PTSD
Status: NOT_YET_RECRUITING
Conditions: Neuropathic Pain|PTSD
Interventions: DRUG: Ketamine|DRUG: Magnesium sulfate|DRUG: Ketamine + Magnesium sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of the Adsorbed Vaccine COVID-19 (Coronavac) Among Education and Public Safety Workers With Risk Factors for Severity
Status: UNKNOWN
Conditions: Covid19
Interventions: BIOLOGICAL: Adsorbed SARS-CoV-2 (inactivated) vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PD-1 Knockout Engineered T Cells for Metastatic Non-small Cell Lung Cancer
Status: COMPLETED
Conditions: Metastatic Non-small Cell Lung Cancer
Interventions: DRUG: Cyclophosphamide|OTHER: PD-1 Knockout T Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study to Evaluate Cyclopofol Injection for the Prevention of Postoperative Nausea and Vomiting
Status: ENROLLING_BY_INVITATION
Conditions: Nausea and Vomiting
Interventions: DRUG: Heptaflurane combined Cyclophenol|DRUG: Heptaflurane|DRUG: Cyclophenol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety And Efficacy Of Hydroxychloroquine For At Risk Population (SHARP) Against COVID-19
Status: WITHDRAWN
Conditions: Coronavirus Infection|Hydroxychloroquine Adverse Reaction
Interventions: DRUG: Hydroxychloroquine Sulfate 200 milligram (mg) Tab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety Study of Deep Brain Stimulation to Manage Thalamic Pain Syndrome
Status: COMPLETED
Conditions: Chronic Pain
Interventions: DEVICE: Deep Brain Stimulation for Thalamic Pain Syndrome
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Repeated Memory Training on Memory Function and Addiction Related Processes
Status: TERMINATED
Conditions: Substance-Related Disorders
Interventions: BEHAVIORAL: Experimental memory training|BEHAVIORAL: Comparator memory training 1|BEHAVIORAL: Comparator memory training 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Selinexor Combined With Standard Chemoradiation as Neoadjuvant Treatment in Locally Advanced Rectal Cancer
Status: UNKNOWN
Conditions: Rectal Neoplasms
Interventions: RADIATION: standard dose pelvic radiation therapy|DRUG: standard dose capecitabine|DRUG: dose-escalated selinexor treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Safety and Immunogenicity of Ad26.Mos4.HIV and CH505 TF chTrimer Combination in Healthy Adults
Status: NOT_YET_RECRUITING
Conditions: Human Immunodeficiency Virus
Interventions: BIOLOGICAL: Ad26.Mos4.HIV [Arm 1]|BIOLOGICAL: Ad26.Mos4.HIV [Arm 2]|BIOLOGICAL: CH505 TF chTrimer+ALFQ [Arm 1]|BIOLOGICAL: CH505 TF chTrimer+ALFQ [Arm 2]|BIOLOGICAL: ALFQ [Arm 1]|BIOLOGICAL: ALFQ [Arm 2]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Oral Tamoxifen vs. TamGel vs. Control in Women With Atypical Hyperplasia, Lobular Carcinoma In Situ, or Increased Breast Cancer Risk
Status: RECRUITING
Conditions: Breast Atypical Hyperplasia|Breast Lobular Carcinoma in Situ|Breast Atypical Lobular Hyperplasia|Breast Carcinoma
Interventions: DRUG: Tamoxifen|DRUG: Topical 4-OHT( 4-hydroxytamoxifen)gel 4 mg/each breast/day|DRUG: Placebo|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An Exploration of Apatinib Combined With S-1 in Patients With Advanced Non-small Cell Lung Cancer
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: Apatinib Mesylate tablet combined with S-1 capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of a Modified-Release Tacrolimus Based Immunosuppression Regimen in Stable Pediatric Liver Transplant Patients
Status: COMPLETED
Conditions: Liver Transplantation
Interventions: DRUG: tacrolimus modified release (MR)|DRUG: tacrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Liver and Metabolic Effects of Insulin Pump Therapy in Diabetics Type 2 With Non-alcoholic Hepatic Steatosis
Status: UNKNOWN
Conditions: Type 2 Diabetes (T2D)
Interventions: PROCEDURE: Insulin pump therapy|PROCEDURE: Multi-injection treatment ( MDI ).
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Trabeculectomy Versus Canaloplasty to Treat Glaucoma
Status: UNKNOWN
Conditions: Glaucoma
Interventions: PROCEDURE: Canaloplasty|PROCEDURE: Trabeculectomy with mitomycin C
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: FNA Tumor Sampling for CD137 Modulation: A Pilot Study
Status: TERMINATED
Conditions: Head and Neck Cancer|Breast Cancer|Head and Neck Cancers|Non-Hodgkin Lymphoma|Colorectal Adenocarcinoma
Interventions: PROCEDURE: FNA Biopsy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of IV Ergonovine With IM Carboprost, With Oxytocin IV, During Cesarean Section for Failure to Progress
Status: COMPLETED
Conditions: Postpartum Hemorrhage
Interventions: DRUG: Oxytocin|DRUG: Ergot|DRUG: Carboprost
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of a New Type of Mechanical Rotational Chair in Treating BPPV
Status: COMPLETED
Conditions: BPPV
Interventions: PROCEDURE: Epley's Maneuver|PROCEDURE: Semont Maneuver|PROCEDURE: 360 degree vertical rotation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial to Evaluate the Recombinant Human Type5 Adenovirus Vector Based Ebola Virus Disease Vaccine
Status: COMPLETED
Conditions: Ebola Disease
Interventions: BIOLOGICAL: Ebola Vaccine|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Safety, Drug-Drug Interactions and Pharmacokinetic Profiles of Co-Administration of Betahistine With Olanzapine in Healthy Female Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Betahistine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Study to Assess Safety,Tolerability,Pharmacokinetics & Antiviral Activity of JTK-853 in Hepatitis C Virus Genotype 1 Infected Subjects
Status: COMPLETED
Conditions: Hepatitis C Virus Infection, Response to Therapy of
Interventions: DRUG: JTK-853|DRUG: Dose 2 JTK-853|DRUG: Dose 3 JTK-853|DRUG: Dose 4 JTK-853|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Pharmacology Study of AZD7295 in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: AZD7295|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Sentinel. Ambulatory. Oral Cavity. Oropharynx (S.A.C.O)
Status: RECRUITING
Conditions: Cancer T1-N0 or T2-N0 of the Oral Cavity
Interventions: PROCEDURE: outpatient surgery for T1-N0 or T2-N0 cancers of the oral cavity or oropharynx with lymph node search
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cerebral Hemodynamics and Microemboli During Placement of Relay®Branch Thoracic Stent-Graft System
Status: ENROLLING_BY_INVITATION
Conditions: Thoracic Aortic Aneurysm|Thoracic Aortic Dissection|Microemboli
Interventions: OTHER: transcranial Doppler ultrasonography (TCD)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Anti-PD-1 Monoclonal Antibody in Advanced, Trastuzumab-resistant, HER2-positive Breast Cancer
Status: COMPLETED
Conditions: Metastatic Breast Cancer
Interventions: DRUG: MK-3475
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Versus Delayed Antiretroviral Therapy (ART) in the Treatment of Cryptococcal Meningitis in Africa
Status: COMPLETED
Conditions: Cryptococcal Meningitis|HIV Infections
Interventions: DRUG: Fluconazole|DRUG: Fixed dose - Stavudine, lamivudine and Nevirapine|DRUG: Fixed dose - Stavudine, Lamivudine, Nevirapine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Implant Placement in Horizontally Deficient Maxillary Aesthetic Zone With Simultaneous Soft Tissue Augmentation
Status: COMPLETED
Conditions: Implant or Graft; Rejection
Interventions: PROCEDURE: implant placement with simultaneous soft tissue augmentation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevention of Postpartum Smoking Relapse in Mothers of Infants in the Neonatal Intensive Care Unit (NICU)
Status: COMPLETED
Conditions: Smoking
Interventions: BEHAVIORAL: Smoking Relapse Prevention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Regorafenib Followed by Nivolumab in Patients With Hepatocellular Carcinoma (GOING)
Status: COMPLETED
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Regorafenib|DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Patient Satisfaction Study of Combined Facial Treatment With BOTOX® Cosmetic, JUVÉDERM® and LATISSE® (HARMONY Study)
Status: COMPLETED
Conditions: Facial Rhytides|Crow's Feet Lines|Glabellar Lines|Nasolabial Fold
Interventions: BIOLOGICAL: onabotulinumtoxinA|DRUG: bimatoprost ophthalmic solution 0.03%|DEVICE: JUVÉDERM® ULTRA XC|DEVICE: JUVÉDERM® ULTRA PLUS XC|DEVICE: JUVÉDERM® VOLUMA® XC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Continuous Positive Airway Pressure (CPAP) Therapy on Outcomes in Patients Undergoing Coronary Revascularization
Status: UNKNOWN
Conditions: Obstructive Sleep Apnea|Ischaemic Heart Desease
Interventions: DEVICE: CPAP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Retrospective Survey Evaluating the Effectiveness and Safety of Dual Inhibition Lipid-lowering in the Treatment of Dyslipidemia (Study P05171)(COMPLETED)
Status: COMPLETED
Conditions: Dyslipidemia
Interventions: DRUG: Ezetimibe 10 mg plus statin or ezetimibe 10 mg plus fenofibrate
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison Between High-flow Nasal Cannula System and Non-invasive Ventilation in Acute Hypoxemic Respiratory Failure
Status: UNKNOWN
Conditions: Acute Hypoxemic Respiratory Failure
Interventions: DEVICE: Non-invasive ventilation|DEVICE: High flow nasal cannula system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Safety of Ilaprazole/Doxycycline-based Bismuth-containing Quadruple Therapy on Hp Infected Duodenal Ulcers
Status: COMPLETED
Conditions: Duodenal Ulcer Due to Helicobacter Pylori
Interventions: DRUG: Doxycycline Hyclate Enteric-Coated Capsules|DRUG: Amoxicillin Capsules|DRUG: Ilaprazole Enteric-Coated Tablets|DRUG: Furazolidone Tablets|DRUG: Potassium Citrate Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Study Assessing the Pharmacokinetics of NEX-22A in Subjects With T2D
Status: RECRUITING
Conditions: Type 2 Diabetes
Interventions: DRUG: NEX-22A, a prolonged release formulation of liraglutide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Simplified Ultrasound Feedback for Speech Remediation
Status: RECRUITING
Conditions: Speech Sound Disorder
Interventions: BEHAVIORAL: Traditional ultrasound biofeedback|BEHAVIORAL: Simplified ultrasound biofeedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Zanubrutinib Plus Tislelizumab Treatment With or Without Sonrotoclax for Patients With Richter Transformation
Status: RECRUITING
Conditions: Richter Transformation
Interventions: BIOLOGICAL: Tislelizumab|DRUG: Zanubrutinib|DRUG: Sonrotoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial of Supplemental CO2 Versus Room Air in Percutaneous Endoscopic Gastrostomy
Status: COMPLETED
Conditions: Pneumoperitoneum
Interventions: PROCEDURE: CO2 insufflation|PROCEDURE: Ambient air insufflation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Treatment Strategies for Severe CaLcIfic Coronary Arteries: Orbital Atherectomy vs. Conventional Angioplasty Technique Prior to Implantation of Drug-Eluting StEnts: The ECLIPSE Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Coronary Artery Disease|Ischemic Heart Disease|Non ST Segment Elevation Myocardial Infarction
Interventions: DEVICE: Orbital Atherectomy|DEVICE: Balloon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Norepinephrine Prevent Post-induction Hypotension in High-risk Patients
Status: NOT_YET_RECRUITING
Conditions: Anesthesia|Blood Pressure|Norepinephrine
Interventions: DRUG: Norepinephrine Hydrochloride|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Perioperative Immunotherapy vs. Chemo-immunotherapy in Patients With Advanced GC and AEG
Status: ACTIVE_NOT_RECRUITING
Conditions: Gastric Cancer|Adenocarcinoma of the Esophagogastric Junction
Interventions: DRUG: Nivolumab|DRUG: relatlimab|DRUG: Oxaliplatin|DRUG: Docetaxel|DRUG: 5-Fluorouracil (5-FU)|DRUG: Folic acid (FA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Examining a Mobile App's Impact on Expectant Fathers' Fear of Childbirth and Paternal Attachment
Status: NOT_YET_RECRUITING
Conditions: Mobile Application|Expectant Fathers|Antenatal Education
Interventions: BEHAVIORAL: Mobile Application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Free Gingival Grafting on Peri-implant Health
Status: RECRUITING
Conditions: Peri-implant Mucositis|Soft Tissue Inflammation
Interventions: PROCEDURE: Non surgical therapy|PROCEDURE: Free gingival Grafting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Registry to Evaluate Patterns of Care Associated With the Use of Corus CAD (or ASGES) in Primary Care Settings
Status: COMPLETED
Conditions: Chest Pain|Coronary Artery Disease|Cardiovascular Diseases|Coronary Heart Disease|Angina Pectoris|CAD|CVD|CHD
Interventions: DIAGNOSTIC_TEST: CORUS CAD (ASGES)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Mechanisms Responsible for Cardiac and Skeletal Muscle Energetic Impairment in Diabetes
Status: UNKNOWN
Conditions: Diabetic Cardiomyopathy
Interventions: DRUG: Perhexiline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Combined Effects of Active Cycle Breathing Technique and Buteyko Technique in Post Sternotomy Patients
Status: RECRUITING
Conditions: Sternotomy
Interventions: OTHER: ACTIVE CYCLE OF BREATHING TECHNIQUE|OTHER: Buteyko techniques
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Effectiveness of Influenza Vaccine Reminder Systems
Status: COMPLETED
Conditions: Asthma|Chronic Obstructive Pulmonary Disease
Interventions: BEHAVIORAL: Postcard and IVR Reminder Group|BEHAVIORAL: Postcard Only Reminder Group|BEHAVIORAL: IVR Only Reminder Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study on Hydronidone Capsule BE
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Hydronidone Capsule(Specification: 30 mg / grain）|DRUG: Hydronidone Capsule(Specification: 15 mg / grain）
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pro-inflammatory Cytokines in Facioscapulohumeral Muscular Dystrophy (CYTOKINE-FSH)
Status: COMPLETED
Conditions: Muscular Dystrophies
Interventions: OTHER: cytokines dosage|PROCEDURE: test of walk|PROCEDURE: Manual muscular test|PROCEDURE: Motrice fonction mesurement
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Evaluation of Well-being Interventions in Adults With TBI
Status: RECRUITING
Conditions: TBI (Traumatic Brain Injury)
Interventions: BEHAVIORAL: Signature Strengths|BEHAVIORAL: TBI Education Course
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prediction and Prevention of Nocturnal Hypoglycemia in Persons With Type 1 Diabetes Using Machine Learning Techniques
Status: COMPLETED
Conditions: Type1diabetes|Hypoglycemia
Interventions: DEVICE: isCGM (intermittently scanned Continuous Glucose Monitoring)|DEVICE: Physical exercise tracker
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: MEDI9447(Oleclumab) Pancreatic Chemotherapy Combination Study.
Status: COMPLETED
Conditions: Carcinoma|Metastatic Pancreatic Adenocarcinoma
Interventions: DRUG: Oleclumab|DRUG: Durvalumab|DRUG: Gemcitabine|DRUG: Nab-paclitaxel|DRUG: Oxaliplatin|DRUG: Folinic acid|DRUG: 5-FU
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: NP-101 (TQ Formula) With Nivolumab and Ipilimumab in Advanced or Metastatic Extra-pulmonary Neuroendocrine Carcinomas
Status: ACTIVE_NOT_RECRUITING
Conditions: Gastroenteropancreatic Neuroendocrine Tumor|Gastroenteropancreatic Neuroendocrine Neoplasm|Neuroendocrine Carcinoma|Mixed Neuroendocrine-Non Neuroendocrine Neoplasm
Interventions: DRUG: NP-101 (TQ Formula)|DRUG: Nivolumab (3mg/kg)|DRUG: Ipilimumab (1mg/kg)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Verapamil Tablets on the Pharmacokinetic of HRS-1893 Tablets in Healthy Subjects
Status: COMPLETED
Conditions: Obstructive Hypertrophic Cardiomyopathy
Interventions: DRUG: HRS-1893 tablet|DRUG: Verapamil tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Cervical Epidural Analgesia on the Occurrence of Pharyngocutaneous Fistula
Status: UNKNOWN
Conditions: Cutaneous Fistula|Laryngectomy
Interventions: DEVICE: cervical epidural analgesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Distraction for Reduction of Pain Associated With Venipuncture in the Pediatric Post-Transplant Population
Status: COMPLETED
Conditions: Pain, Procedural|Distress, Procedural|Venipuncture
Interventions: OTHER: Distraction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effects of Nutritional Supplementation and Drug Abuse on HIV
Status: COMPLETED
Conditions: HIV Infections|Substance-Related Disorders
Interventions: DIETARY_SUPPLEMENT: Multivitamins|DIETARY_SUPPLEMENT: Selenium|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare the NexGen CR and CR-Flex Knee Implants
Status: COMPLETED
Conditions: Total Knee Arthroplasty|Osteoarthritis
Interventions: DEVICE: NexGen CR-Flex Fixed Bearing Knee|DEVICE: NexGen CR Knee
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Investigation of Ocular Signs & Symptoms in Wearers Fitted With Contact Lenses Following Digital Device Use
Status: COMPLETED
Conditions: Visual Performance
Interventions: DEVICE: Marketed Soft Contact lens|DEVICE: AIR OPTIX® AQUA|DEVICE: Biofinity®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficiency and Safety of Different Treatment Strategies in Adults With Pituitary Adenomas With Hypothalamic Involvement
Status: NOT_YET_RECRUITING
Conditions: Pituitary Adenoma
Interventions: PROCEDURE: Total resection|PROCEDURE: Staged resection|PROCEDURE: Subtotal resection followed by stereotactic radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I Study of Oral LGX818 in Adult Patients With Advanced or Metastatic BRAF Mutant Melanoma
Status: COMPLETED
Conditions: Melanoma and Metastatic Colorectal Cancer
Interventions: DRUG: LGX818
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Conformal Sphincter-Preservation Operation Versus InterSphincteric Resection on Anal Function in Low Rectal Cancer
Status: NOT_YET_RECRUITING
Conditions: Rectum Cancer
Interventions: PROCEDURE: CSPO|PROCEDURE: ISR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Epinephrine Sprayed on the Papilla for the Prevention of Post-ERCP Pancreatitis
Status: UNKNOWN
Conditions: Post-ERCP Acute Pancreatitis
Interventions: DRUG: epinephrine|DRUG: normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Combined IV and Topical TXA in Major Spine Surgery
Status: RECRUITING
Conditions: Spine Surgery|Back Pain
Interventions: DRUG: High Dose Tranexamic acid|DRUG: Low Dose Tranexamic acid|DRUG: Tranexamic acid Topical|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Soy Isoflavones on Bone Mineral Density and Physical Performance Indices
Status: COMPLETED
Conditions: Osteoporosis
Interventions: DIETARY_SUPPLEMENT: Soy protein
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Roentgen Stereophotogrammetric Analysis (RSA) to Evaluate Fixation of Biofoam Advance Total Knee Arthroplasty Components
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DEVICE: Advance Biofoam porous metal backed tibial component with or without screw augmentation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: High-intensity Rosuvastatin vs. Moderate-intensity Rosuvastatin/Ezetimibe in High Atherosclerotic Cardiovascular Disease Risk Patients With Type 2 Diabetes
Status: UNKNOWN
Conditions: Atherosclerotic Cardiovascular Disease|Type 2 Diabetes
Interventions: DRUG: Rosuvamibe|DRUG: Monorova
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Impact of Bacteriuria on Chronic Inflammation in Asymptomatic Hemodialysis Patients
Status: UNKNOWN
Conditions: Inflammation on Dialysis|Bacteriuria in Hemodialysis Patients
Interventions: OTHER: Antibiotic treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluate Efficacy, Tolerability & Safety of Combination of Clindamycin and Ketoconazole for the Treatment of Mixed-Type Vaginosis, Bacterial Vaginosis and Candidiasis
Status: UNKNOWN
Conditions: Candidiasis|Bacterial Vaginosis
Interventions: DRUG: Clindamycin 100mg and Ketoconazole 400mg|DRUG: Tetracycline 100mg and Amphotericin B 50mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Evaluate Immunogenicity, Reactogenicity & Safety of 2 Doses of GSK Bio HRV Liquid Vaccine Given to Infants (Vietnam)
Status: COMPLETED
Conditions: Infections, Rotavirus
Interventions: BIOLOGICAL: Human rotavirus liquid vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Alcohol and "Heat of the Moment" Sexual Decision Making
Status: RECRUITING
Conditions: Alcohol Drinking|Sex, Unsafe|Hiv
Interventions: BEHAVIORAL: Self-Regulation Intervention|BEHAVIORAL: Brief Advice and Information
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Prevention of Graft-Versus-Host Disease in Patients With Advanced Leukemia or Lymphoma Who Are Eligible for Peripheral Stem Cell Transplantation
Status: TERMINATED
Conditions: Leukemia|Lymphoma|Graft Versus Host Disease
Interventions: DRUG: cyclosporine|DRUG: cyclosporine and methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: |Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effects of Antenatal Interventions With Artistic Content Given to Pregnant Women
Status: COMPLETED
Conditions: Antenatal Care|Mental Health
Interventions: BEHAVIORAL: Laughter therapy+Music listening+Keeping diary
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of Standard Versus Extended Nicotine Patch Therapy for Smoking Cessation
Status: COMPLETED
Conditions: TOBACCO USE CESSATION
Interventions: DRUG: Standard Patch Treatment|DRUG: 24-weeks of nicotine patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Community Health Worker/Pharmacist Team to Improve Blood Sugars in Diabetes Care Using Continuous Glucose Monitoring
Status: NOT_YET_RECRUITING
Conditions: Type 2 Diabetes
Interventions: BEHAVIORAL: Pharmacist Only|DEVICE: Continuous Glucose Monitor (CGM)|BEHAVIORAL: Community Health Worker (CHW)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Plasma Total Antioxidant Status and Thiobarbituric Acid-reacting Substances in Patients With Inguinal Hernia
Status: COMPLETED
Conditions: Inguinal Hernia
Interventions: PROCEDURE: Procedures of hernia repair.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT