pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: LLETZ Under Direct Colposcopic Vision
Status: COMPLETED
Conditions: Uterine Cervical Dysplasia
Interventions: DEVICE: LLETZ with colposcopy|OTHER: LLETZ without colposcopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Video Assisted Pericardioscopic Surgery: Minimal-invasive Implantation of Epimyocardial Pacemaker Leads in Humans
Status: UNKNOWN
Conditions: Dysrhythmia, Cardiac|Heart Failure|Pacemaker Electrode Infection|Hemodialysis-Induced Symptom|Bradycardia
Interventions: DEVICE: StingrayTM, Medtronic®
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cytokine-Treated Veto Cells in Treating Patients With Hematologic Malignancies Following Stem Cell Transplant
Status: RECRUITING
Conditions: Acute Lymphoblastic Leukemia|Acute Myeloid Leukemia|Aplastic Anemia|Bone Marrow Failure|Chronic Lymphocytic Leukemia|Chronic Myelogenous Leukemia, BCR-ABL1 Positive|Follicular Lymphoma|Hodgkin Lymphoma|Mantle Cell Lymphoma|Myelodysplastic Syndrome|Myeloproliferative Neoplasm|Non-Hodgkin Lymphoma|Plasma Cell Myeloma
Interventions: BIOLOGICAL: Anti-Thymocyte Globulin|DRUG: Cyclophosphamide|BIOLOGICAL: Cytokine-treated Veto Cells|DRUG: Fludarabine|PROCEDURE: Peripheral Blood Stem Cell Transplantation|RADIATION: Total-Body Irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Probiotic Supplementation for Those Immune Non-responders With HIV-1 Infection
Status: RECRUITING
Conditions: HIV-infection/Aids
Interventions: DIETARY_SUPPLEMENT: Bifidobacteria and Lactobacilli triple viable capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Trial on the Effect of Budesonide/Formoterol and Inhaled Budesonide Alone on Exercise-Induced Asthma
Status: TERMINATED
Conditions: Exercise Induced Asthma
Interventions: DRUG: Budesonide/Formoterol|DRUG: Budesonide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ModraDoc006/r vs Docetaxel IV in Metastatic Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer Metastatic|Castration-resistant Prostate Cancer
Interventions: DRUG: Docetaxel in Parenteral Dosage Form|DRUG: ModraDoc006/r
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sacituzumab Tirumotecan (MK-2870) Versus Chemotherapy in Previously Treated Advanced or Metastatic Nonsquamous Non-small Cell Lung Cancer (NSCLC) With EGFR Mutations or Other Genomic Alterations (MK-2870-004)
Status: RECRUITING
Conditions: Non-small Cell Lung Cancer (NSCLC)
Interventions: BIOLOGICAL: Sacituzumab tirumotecan|DRUG: Docetaxel|DRUG: Pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Evaluate the Efficacy and Safety of CAN008 Combined With Re-irradiation (rRT) for Treating Patients With Recurrent Glioblastoma (GBM)
Status: UNKNOWN
Conditions: GBM
Interventions: DRUG: CAN008
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Senolytics Treatment of Interstitial Lung Disease in Common Variable Immunodeficiency
Status: ENROLLING_BY_INVITATION
Conditions: Common Variable Immunodeficiency|Interstitial Lung Disease Due to Systemic Disease
Interventions: DRUG: Fisetin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bronchoscopy vs. Clinical Pulmonary Infection Score Guided Approach in Suspected Ventilator-Associated Pneumonia (VAP)
Status: WITHDRAWN
Conditions: Ventilator Associated Pneumonia
Interventions: PROCEDURE: Bronchoscopy|PROCEDURE: Clinical pulmonary infection score (CPIS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: How Vitamin D Analogues Affect Endothelial Cells in Patients on Dialysis
Status: COMPLETED
Conditions: Hyperparathyroidism, Secondary|Kidney Failure, Chronic
Interventions: DRUG: doxercalciferol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neurocognitive Mechanisms Underlying Smartphone-Assisted Prevention of Relapse in Opioid Use Disorder
Status: ENROLLING_BY_INVITATION
Conditions: Opioid-Related Disorders|Mobile Applications|Opiate Substitution Treatment|Magnetic Resonance Imaging|Craving|Attentional Bias|Ecological Momentary Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Post-stroke Fatigue, Inflammation, tDCS
Status: COMPLETED
Conditions: Stroke|Fatigue|Chronic Stroke|Stroke Sequelae
Interventions: DEVICE: anodal transcranial direct current stimulation (a-tDCS)|DEVICE: sham stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Randomized Trial of Clinical Decision Making in Asymptomatic Carotid Stenosis
Status: COMPLETED
Conditions: Carotid Stenosis
Interventions: OTHER: One of 6 video presentation by one of 4 presenters
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Gene Transfer for X-Linked Severe Combined Immunodeficiency in Newly Diagnosed Infants
Status: SUSPENDED
Conditions: Severe Combined Immunodeficiency Disease, X-linked
Interventions: GENETIC: CL20-i4-EF1α-hγc-OPT|DRUG: Busulfan|DEVICE: CliniMacs
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cetuximab, Cisplatin, Fluorouracil, and Radiation Therapy in Treating Patients With Anal Cancer
Status: COMPLETED
Conditions: Anal Cancer
Interventions: BIOLOGICAL: cetuximab|DRUG: cisplatin|DRUG: fluorouracil|RADIATION: radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Of Pregabalin In The Treatment Of Pancreatic Cancer Pain. A Randomized Controlled Double-Blind, Parallel Group Study
Status: TERMINATED
Conditions: Pancreatic Cancer|Visceral Pain
Interventions: DRUG: Placebo|DRUG: Pregabalin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Metabolic Characterization of Space Occupying Lesions of the Brain
Status: RECRUITING
Conditions: Brain Tumor|Glioma|IDH Mutation
Interventions: DEVICE: MR-scans using a 3T Prisma and a 7T Terra scanner (Siemens, Erlangen Germany)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: FFP In Traumatic BRAin INjury (FIT-BRAIN) Trial
Status: NOT_YET_RECRUITING
Conditions: Moderate to Severe Traumatic Brain Injury
Interventions: BIOLOGICAL: Fresh Frozen Plasma (FFP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: LUCY: A Study for the Treatment of Non-Small Cell Lung Cancer (NSCLC) in Patients Previously Treated With Chemotherapy
Status: COMPLETED
Conditions: Lung Cancer|Cancer of Lung|Cancer of the Lung|Non-Small Cell Lung Carcinoma|Carcinoma, Non-Small Cell Lung
Interventions: DRUG: YM155
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Inflammation, Immune Activation and Portal Hypertension in Alcoholic Hepatitis
Status: COMPLETED
Conditions: Alcoholic Hepatitis
Interventions: DEVICE: Prometheus Liver Dialysis system (Fresenius Medical Care)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Safety of Prandial Inhalation of Technosphere/Insulin in Combination With Metformin or Technosphere/Insulin Alone Versus 2 Oral Anti-Diabetic Agents in Subjects With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Technosphere Insulin|DRUG: Metformin & Secretagogues|DRUG: Technosphere Insulin & Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Cera™ Patent Foramen Ovale Occluders.
Status: RECRUITING
Conditions: Patent Foramen Ovale|Cryptogenic Stroke
Interventions: DEVICE: Cera™ patent foramen ovale occluders|DEVICE: Another patent foramen ovale occluders
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Performance of Two Daily Disposable Toric Soft Contact Lenses
Status: COMPLETED
Conditions: Refractive Errors|Ametropia|Astigmatism
Interventions: DEVICE: Verofilcon A toric contact lenses|DEVICE: Etafilcon A toric contact lenses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Feasibility of ADRCs (Adipose Derived Regenerative Cells) in Patients With Grade II Hamstring Tears
Status: WITHDRAWN
Conditions: Muscle Tear
Interventions: DEVICE: ADRCs prepared by investigational Celution Device|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mechanisms Underlying the Protective Vascular Effects of Dietary Potassium in Humans
Status: RECRUITING
Conditions: Cardiovascular Risk Factor
Interventions: OTHER: Moderate Potassium/Low Sodium Diet|OTHER: Moderate Potassium/High Sodium Diet|OTHER: High Potassium/High Sodium Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Intranasal Oxytocin and Food Intake in Obese Adolescents
Status: WITHDRAWN
Conditions: Obesity
Interventions: DRUG: Syntocinon|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Connective Tissue Massage With Fibromyalgia
Status: COMPLETED
Conditions: Fibromyalgia
Interventions: OTHER: Connective Tissue Massage|OTHER: clinical pilates exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vinorelbine and Oxaliplatin (Vinox) With or Without Trastuzumab (Herceptin®) in Advanced Breast Carcinoma
Status: TERMINATED
Conditions: Breast Neoplasms
Interventions: DRUG: Oxaliplatin|DRUG: vinorelbine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Study to Evaluate the Safety and Tolerability of DS-1040b IV Infusion With Clopidogrel in Healthy Subjects
Status: COMPLETED
Conditions: Drug Interaction
Interventions: DRUG: DS-1040b|DRUG: Clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Allogeneic Blood Stem Cell Transplantation and Adoptive Immunotherapy for Hodgkin's Disease
Status: COMPLETED
Conditions: Hodgkin's Disease
Interventions: DRUG: Gemcitabine|DRUG: Fludarabine|DRUG: Melphalan|DRUG: Antithymocyte Globulin|PROCEDURE: Allogeneic Stem Cell Infusion|DRUG: Tacrolimus|DRUG: Filgrastim (G-CSF)|DRUG: Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 3 Study of Etrasimod in Subjects With Moderately to Severely Active Ulcerative Colitis
Status: ACTIVE_NOT_RECRUITING
Conditions: Moderately to Severely Active Ulcerative Colitis
Interventions: DRUG: Etrasimod|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase III Intensity Radiotherapy Dose Escalation for Prostate Cancer Using Hypofractionation
Status: UNKNOWN
Conditions: Prostate Cancer
Interventions: RADIATION: Conventional Fractionated Intensity Modulated Radiotherapy|RADIATION: Hypofractionated Intensity Modulated Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Heel Pain in Adolescents: A Pilot Study on the Effectiveness of Exercise Therapy and Activity Modification
Status: COMPLETED
Conditions: Sever's Disease|Achilles Tendinopathy|Insertional Achilles Tendinopathy|Apophysitis; Calcaneus
Interventions: OTHER: Exercise Therapy and Activity Modification
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: mHealth India Postnatal Health Intervention Effectiveness
Status: NOT_YET_RECRUITING
Conditions: Health Knowledge, Attitudes, Practice|Post Partum Depression|Breastfeeding|Nutrition, Healthy
Interventions: BEHAVIORAL: MESSSSAGE intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Follow-up to Welcome Study C87042 [NCT00308581] Examining Certolizumab Pegol (CDP870) in Subjects With Crohn's Disease
Status: COMPLETED
Conditions: Crohn's Disease
Interventions: BIOLOGICAL: Certolizumab pegol (CDP870)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PEP005 Gel - Evaluation of the Safety and Efficacy of Ingenol Mebutate Gel on a Superficial Basal Cell Carcinoma on the Trunk or Extremities
Status: COMPLETED
Conditions: Superficial Basal Cell Carcinoma
Interventions: DRUG: PEP005 (ingenol mebutate) Gel, 0.05%|DEVICE: Aluminium disk|DEVICE: OpSite(TM) disk
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anabolic Effects of Whey and Casein After Strength Training in Young and Elderly
Status: COMPLETED
Conditions: Healthy|Young|Elderly
Interventions: OTHER: Strength training|DIETARY_SUPPLEMENT: Milk 1%|DIETARY_SUPPLEMENT: Whey protein concentrate 80|DIETARY_SUPPLEMENT: Native whey
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Posterior Maxillary Ridge Augmentation With Sinus Lift Using Mineralized Plasmatic Matrix Versus Autogenous Bone Graft
Status: UNKNOWN
Conditions: Bone Resorption
Interventions: OTHER: autogenous bone|OTHER: Mineralized plasmatic matrix
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Investigation of the Safety of the MediSieve Magnetic Haemofiltration System in Healthy Volunteers
Status: COMPLETED
Conditions: Haemofiltration
Interventions: DEVICE: MediSieve Magnetic Haemofiltration System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neem Lotion With Combing for Lice
Status: COMPLETED
Conditions: Pediculoses|Head Lice
Interventions: DEVICE: Neem-based lotion plus louse comb|DEVICE: Neem-based lotion plus grooming comb
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Point-of-care Ultrasound in Finland
Status: COMPLETED
Conditions: Deep Vein Thrombosis|Abdominal Aortic Aneurism|Pneumothorax|Gallbladder Diseases|Hydronephrosis|Pregnancy, Ectopic|Ascites|Pleural Effusion|Pericardial Effusion
Interventions: DIAGNOSTIC_TEST: Point-of-care ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Multicell Air Cushions: Sitting Posture and Limits of Stability
Status: ENROLLING_BY_INVITATION
Conditions: Wheelchairs|Self-Help Devices|Posture|Sitting Position|Limits of Stability|Balance
Interventions: DEVICE: Wheelchair air cushion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessing the Accuracy of Seismofit® as an Estimate of VO2 Peak in Patients With Hepato-pancreato-biliary, Colorectal, and Gastro-oesophageal Cancer
Status: RECRUITING
Conditions: Hepato-Biliary Carcinoma in Situ Nos|Pancreatic Cancer|Colorectal Cancer|Gastric Cancer|Oesophageal Cancer
Interventions: OTHER: Non-Interventional
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: MAD Study Evaluating the Safety, Tolerability, and Pharmacokinetic Effects of N91115 in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: N91115|DRUG: Placebo|DRUG: N91115|DRUG: Placebo-Day 1 only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of MLN4924, a Novel Inhibitor of Nedd8 Activating Enzyme, in Adult Patients With Lymphoma or Multiple Myeloma
Status: COMPLETED
Conditions: Hematologic Malignancies|Multiple Myeloma|Lymphoma|Hodgkin Lymphoma
Interventions: DRUG: MLN4924
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Development and Evaluation of a Novel Portable Robotic Gait Rehabilitation in Chronic Stroke
Status: UNKNOWN
Conditions: Stroke
Interventions: OTHER: Conventional Gait Training|DEVICE: Gait rehabilitation with walker
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dose Escalation Trial to Evaluate Dose Limiting Toxicity/Maximum Tolerated Dose of Microneedle Arrays Containing Doxorubicin (D-MNA) in Basal Cell Carcinoma (BCC)
Status: TERMINATED
Conditions: Basal Cell Carcinoma
Interventions: DRUG: Placebo-containing MNA|DRUG: 25 µg doxorubicin-containing MNA|DRUG: 50 µg doxorubicin-containing MNA|DRUG: 100 µg doxorubicin-containing MNA|DRUG: 200 µg doxorubicin-containing MNA
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transcutaneous Medial Plantar Nerve Stimulation in Women With Idiopathic Overactive Bladder
Status: NOT_YET_RECRUITING
Conditions: Urinary Bladder, Overactive
Interventions: OTHER: Transcutaneous medial plantar nerve stimulation (T-MPNS)|OTHER: Sham Transcutaneous medial plantar nerve stimulation (T-MPNS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Safety, Tolerability, and Pharmacokinetic Study of QLM3003 in Healthy Adult Subjects
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: QLM3003|DRUG: QLM3003 Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Safety, Tolerability and Pharmacokinetics of Fimepinostat (CUDC-907) in Patients With Lymphoma
Status: COMPLETED
Conditions: Lymphoma|Relapsed Lymphoma|Refractory Lymphoma|Relapsed and/or Refractory Lymphoma|Relapsed Ddiffuse Large B-Cell Lymphoma (DLBCL)|Refractory Diffuse Large B-Cell Lymphoma (DLBCL)|Relapsed and/or Refractory Diffuse Large B-Cell Lymphoma (DLBCL)|Double-hit Lymphoma (DHL)|Triple-hit Lymphoma (THL)|Double-expressor Lymphoma (DEL)|High-grade B-cell Lymphoma (HGBL)
Interventions: DRUG: fimepinostat|DRUG: Rituximab|DRUG: venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of JUC as Hand Rub Evaluated by Using European Standard 1500
Status: COMPLETED
Conditions: Infectious Disease Transmission
Interventions: DRUG: JUC solution|DRUG: propan-2-ol
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: THRIVE Feasibility Trial
Status: COMPLETED
Conditions: Surgery--Complications|Anesthesia Complication|Anesthesia Awareness|Anesthesia Emergence Delirium|Anesthesia|Surgery|Quality of Life|Pain, Postoperative|Nausea, Postoperative|Anesthesia Morbidity|Depression|Sleep Disorders, Circadian Rhythm
Interventions: OTHER: Anesthetic technique Propofol TIVA|OTHER: Anesthetic technique inhaled agent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Investigating the Effects of Neuromobilization in Lateral Epicondylitis
Status: COMPLETED
Conditions: Tennis Elbow|Lateral Epicondylitis
Interventions: OTHER: Radial nerve mobilization|OTHER: Supervised home program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Ginkgo Biloba Extract on Cognitive Function in Acute Ischemic Stroke
Status: NOT_YET_RECRUITING
Conditions: Acute Ischemic Stroke
Interventions: DRUG: Ginkgo Biloba Extract
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Human Autologous Peripheral Blood Stem Cells for Treatment of HBV-related Liver Cirrhosis
Status: UNKNOWN
Conditions: Liver Cirrhosis|End Stage Liver Disease
Interventions: OTHER: PBSC transplantation|OTHER: conventional treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dry Needling vs Dry Needling With ES in Patients With Neck/Shoulder Pain
Status: COMPLETED
Conditions: Myofascial Pain|Neck Pain|Shoulder Pain
Interventions: PROCEDURE: Dry needling (DN)|PROCEDURE: Dry needling with intramuscular electrical stimulation (DNES)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial Investigating the Total Exposure of NN5401 (Insulin Degludec/Insulin Aspart) in Children, Adolescents and Adult Subjects With Type 1 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 1
Interventions: DRUG: insulin degludec/insulin aspart
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: myAirvo 3 (High Flow Nasal Therapy; HFNT) for COPD Patients in the Home
Status: RECRUITING
Conditions: COPD
Interventions: DEVICE: myAirvo3|DEVICE: Pulse oximeter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reducing Contact Centre Call Agents' Sitting Time
Status: COMPLETED
Conditions: Sedentary Lifestyle|Physical Activity
Interventions: BEHAVIORAL: Education and training sessions|BEHAVIORAL: Support emails|BEHAVIORAL: Team leader training|DEVICE: Height-adjustable workstation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Dupilumab for the Treatment of Chronic Spontaneous Urticaria in Patients Who Remain Symptomatic Despite the Use of H1 Antihistamine and Who Are naïve to, Intolerant of, or Incomplete Responders to Omalizumab (LIBERTY-CSU CUPID)
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Spontaneous Urticaria
Interventions: DRUG: Dupilumab SAR231893|DRUG: Placebo|DRUG: non sedating H1-antihistamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lorcaserin Intra Venous Cocaine Effects
Status: UNKNOWN
Conditions: Cocaine Use Disorders
Interventions: DRUG: Lorcaserin, 10 mg|DRUG: Lorcaserin, 20 mg|OTHER: Oral Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Ergon Instruments-Assisted Soft Tissue Mobilization With Compressive Myofascial Release
Status: COMPLETED
Conditions: Plantar Fasciitis
Interventions: OTHER: Instrument-assisted Soft Tissue Mobilization|OTHER: Compressive Myofascial Release Technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination of Methotrexate(MTX) and Actinomycin(ACTD) in the Low Risk Gestational Trophoblastic Neoplasma （GTN） Patients With Score of 5-6
Status: UNKNOWN
Conditions: Gestational Trophoblastic Tumor|Effects of Chemotherapy|Drug Toxicity
Interventions: DRUG: MTX|DRUG: MTX+ACTD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Characterisation of the Cognitive Profile of Patients Suffering From Friedreich's Ataxia
Status: NOT_YET_RECRUITING
Conditions: Friedreich Ataxia
Interventions: GENETIC: friedreich Ataxia
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Clinical Trial With Diclofenac Sodium Medicated Plaster in Patients With Impact Injuries of the Limbs
Status: COMPLETED
Conditions: Trauma Injury|Inflammation
Interventions: DRUG: Diclofenac Sodium 140 mg medicated plaster|DRUG: Diclofenac epolamine (DIEP) 180mg medicated plaster, Flector|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Bridging Study on Efficacy and Safety of [18F]Florbetaben PET for Diagnosis of Alzheimer Disease Subjects in Chinese Population
Status: COMPLETED
Conditions: Alzheimer Disease|Dementia|Brain Diseases|Central Nervous System Diseases|Nervous System Diseases|Tauopathies|Neurodegenerative Diseases|Neurocognitive Disorders|Mental Disorders
Interventions: DRUG: Drug: [18F]florbetaben
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Phase II Trial of Neoadjuvant Treatment With PD-1 Inhibition (Nivolumab) With or Without IDO Inhibition (BMS-986205) and With or Without CTLA-4 Inhibition (Ipilimumab) in Resectable Stage III or IV Melanoma
Status: WITHDRAWN
Conditions: Melanoma Stage III|Melanoma Stage IV
Interventions: DRUG: Nivolumab|DRUG: BMS-986205|DRUG: Ipilimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ifenprodil Tartrate Treatment of Adolescents With Post-traumatic Stress Disorder: a Double-blind, Placebo-controlled Trial
Status: COMPLETED
Conditions: Posttraumatic Stress Disorders
Interventions: DRUG: Ifenprodil Tartrate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Peer Mentorship: An Intervention To Promote Effective Pain Self-Management In Adolescents
Status: COMPLETED
Conditions: Irritable Bowel Syndrome (IBS)|Functional Abdominal Pain|Fibromyalgia|Complex Regional Pain Syndrome (CRPS)|Myofacial Pain|Chronic Daily Headaches|Migraine Headaches|Chronic Pain
Interventions: BEHAVIORAL: Mentorship
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Iron and/or Zinc Supplementation in Mexican School Children Exposed to Lead
Status: COMPLETED
Conditions: Lead Poisoning
Interventions: DIETARY_SUPPLEMENT: Ferrous fumarate|DIETARY_SUPPLEMENT: Zinc oxide|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Evening Versus Morning Levothyroxine Intake in Elderly
Status: UNKNOWN
Conditions: Aging|Primary Hypothyroidism|Interaction Drug Food
Interventions: OTHER: Evening Levothyroxine Administration|OTHER: Morning Levothyroxine Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Home-based Pulmonary Rehabilitation in Patients With Severe or Very Severe Chronic Obstructive Pulmonary Disease (COPD)
Status: UNKNOWN
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: OTHER: domiciliary rehabilitation|OTHER: Standard Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Prospective Randomized Comparison Trial on the Use of Mifepristone With Sublingual or Buccal Misoprostol for Medical Abortions of Less Than 9 Weeks Gestation
Status: COMPLETED
Conditions: Abortion, Legal
Interventions: DRUG: Misoprostol|DRUG: Misoprostol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transcranial Direct Current Stimulation for Depression in Alzheimer's Disease Patient - Preliminary Research
Status: TERMINATED
Conditions: Alzheimer Disease|Depression
Interventions: DEVICE: Transcranial Direct Current Stimulation|OTHER: Sham Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A PROSPECTIVE, MULTI-CENTER, SINGLE-ARM, POST MARKET OBSERVATIONAL STUDY TO EVALUATE THE SAFETY AND CLINICAL PERFORMANCE OF THE ARCHIMEDES BIODEGRADABLE BILIARY AND PANCREATIC STENT
Status: RECRUITING
Conditions: Obstructed Biliary and Pancreatic Duct
Interventions: DEVICE: ARCHIMEDES Biodegradable Biliary and Pancreatic Stent
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Antineoplaston Therapy on the QT/QTc Interval In Subjects With Diffuse, Intrinsic, Brainstem Glioma
Status: NOT_YET_RECRUITING
Conditions: Brain Stem Glioma
Interventions: RADIATION: Radiation|DRUG: Atengenal|DRUG: Astugenal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Phase II Randomized Study of Alendronate Sodium for Osteopenia in Patients With Gaucher's Disease
Status: COMPLETED
Conditions: Gaucher's Disease|Osteopenia
Interventions: DRUG: alendronate sodium|DRUG: calcium carbonate|DRUG: cholecalciferol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Clinical Performance and Safety of an Intra-articular Hyaluronic Acid in Knee Osteoarthritis
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: DEVICE: HL-01: high and low molecular weight hyaluronic acid|DEVICE: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Piloting an Enhanced Protocol of Occupational Therapy in an Equine Environment for Youth With Autism
Status: COMPLETED
Conditions: Autism Spectrum Disorder
Interventions: BEHAVIORAL: Occupational Therapy in an Equine Environment|BEHAVIORAL: Occupational Therapy in a Clinic (OTC)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy in Treating Patients Who Have Advanced Solid Tumors
Status: COMPLETED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: FOLFIRI regimen|DRUG: fluorouracil|DRUG: irinotecan hydrochloride|DRUG: leucovorin calcium
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Clinical Study of the Safety and Immunogenicity of a Recombinant Viral Vector AAV5 (Adeno-Associated Virus Type 5 )-RBD (Receptor Binding Domain)-S Vaccine for the Prevention of Coronavirus Infection (COVID-19)
Status: TERMINATED
Conditions: Coronavirus Infection|COVID-19
Interventions: BIOLOGICAL: Low dose BCD-250 injection|BIOLOGICAL: High dose BCD-250 injection|BIOLOGICAL: Low dose or high dose BCD-250 injection|OTHER: Placebo injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Postprandial Amino Acid Response After Protein Consumption
Status: UNKNOWN
Conditions: Sarcopenia
Interventions: DIETARY_SUPPLEMENT: milk protein|DIETARY_SUPPLEMENT: micellar casein|DIETARY_SUPPLEMENT: pea protein|DIETARY_SUPPLEMENT: milk/pea protein blend
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Peroneal and Achilles Tendon Repair Indications With CLARIX® CORD 1K
Status: COMPLETED
Conditions: Peroneal and Achilles Tendon Tears
Interventions: OTHER: CLARIX® CORD 1K graft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Combination of Everolimus and 177Lu-DOTATATE in the Treatment of Grades 2 and 3 Refractory Meningioma: a Phase IIb Clinical Trial
Status: NOT_YET_RECRUITING
Conditions: Meningioma
Interventions: DRUG: Everolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Waveform Periodicity Analysis in Patients With Persistent Atrial Fibrillation
Status: RECRUITING
Conditions: Atrial Fibrillation
Interventions: OTHER: Mapping strategy|OTHER: Mapping strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Human Umbilical Cord Mesenchymal Stem Cell(UC-MSC)Delayed Renal Chronic Kidney Disease(CKD3、4 )
Status: UNKNOWN
Conditions: Chronic Kidney Diseases
Interventions: BIOLOGICAL: UC-MSC|BIOLOGICAL: Saline solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: To Evaluate the Long-Term Safety and Efficacy of Pregabalin in Patients With Partial Seizures
Status: COMPLETED
Conditions: Seizure Disorder, Partial
Interventions: DRUG: Pregabalin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of CoQ10 on the Endocrine Function of Skeletal Muscle
Status: NOT_YET_RECRUITING
Conditions: Ischemic Preconditioning|Coenzyme Q Deficiency|Exercise Training
Interventions: DIETARY_SUPPLEMENT: CoQ10 supplementation|PROCEDURE: Ischemic preconditioning training|DIETARY_SUPPLEMENT: IPC training combined with CoQ10 supplementation|DIETARY_SUPPLEMENT: Sham IPC combined with placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Monitoring of Pulse Index Continuous Cardiac Output (PiCCO) on Shock Patients in Intensive Care Unit
Status: UNKNOWN
Conditions: Shock
Interventions: DEVICE: PiCCO|OTHER: sham, no intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Local Moxifloxacin and Povidone Iodine Versus Povidone Iodine Alone as a Prophylaxis Before Eye Operations
Status: UNKNOWN
Conditions: Eye Infections
Interventions: DRUG: Moxifloxacin and Povidone Iodine vs Povidone Iodine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Single Ascending Dose Study of PCSK-9 Inhibitor (IBI306) in Healthy Subjects.
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DRUG: IBI306|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: A Study of LY2189265 and Sitagliptin in Participants With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: BIOLOGICAL: LY2189265|DRUG: Sitagliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gait Asymmetry Assessed Using Portable Gait Analysis System
Status: COMPLETED
Conditions: Ankle Osteoarthritis|Knee Osteoarthritis|Hip Osteoarthritis|Lumbar Spine Stenosis|Muscle Contracture
Interventions: PROCEDURE: arthroplasty|OTHER: manual therapy|PROCEDURE: lumbar spinal stenosis decompression
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Tacrolimus After rATG and Infliximab Induction Immunosuppression (RIMINI)
Status: COMPLETED
Conditions: Renal Transplant Rejection
Interventions: DRUG: Antithymocyte Immunoglobulin (Rabbit)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Methadone Pharmacokinetics and Cardiac Effects in Newborns
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Methadone HCl Inject 10 mg/ml (will require dilution)|DRUG: Methadone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Integrating the Clinical Pharmacists Into Emergency Department Teams
Status: ACTIVE_NOT_RECRUITING
Conditions: Emergency Department|Clinical Pharmacist
Interventions: OTHER: Introducing clinical pharmacists to the interdisciplinary ED team.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Meaning-Centered Psychotherapy in Advanced Cancer
Status: COMPLETED
Conditions: Lymphoma, Non-Hodgkin|Neoplasms
Interventions: BEHAVIORAL: Meaning-Centered Group Psychotherapy|BEHAVIORAL: Standard Supportive Group Psychotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: ECT
Clinical trial: Effect of Human Thrombin With Gelatin Matrix on Perioperative Blood Loss in Scoliosis Surgery
Status: COMPLETED
Conditions: Adolescent Idiopathic Scoliosis
Interventions: DEVICE: Gelatin matrix with human derived thrombin (Floseal, Baxter)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Erector Spinae Plane Block on Postoperative Pain Following Lumbar Fusion Surgery
Status: NOT_YET_RECRUITING
Conditions: Fusion of Spine, Lumbar Region|Anesthesia, Local|Pain, Postoperative|Opioid Use
Interventions: PROCEDURE: Erector Spinae Plane Block|PROCEDURE: Subcutaneous Anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Dose Range Finding Study of JNJ-39758979 in Patients With Active Rheumatoid Arthritis Currently Treated With Methotrexate
Status: WITHDRAWN
Conditions: Active Rheumatoid Arthritis; Rheumatoid Arthritis
Interventions: DRUG: Placebo/JNJ-39758979 (300 mg/d)|DRUG: JNJ-39758979 (10 mg)|DRUG: JNJ-39758979 (30 mg)|DRUG: JNJ-39758979 (100 mg)|DRUG: JNJ-39758979 (300 mg)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Message Framing and Time Discounting on Health Communication for Optimum Cardiovascular Disease and Stroke Prevention
Status: COMPLETED
Conditions: Cardiovascular Disease|Stroke|Primary Prevention
Interventions: OTHER: The strategic use of messages in risk communication
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of Pre-op and Post-op Pectoralis Nerve Block
Status: COMPLETED
Conditions: Breast Cancer|Postoperative Pain|Anesthesia|Nerve Block
Interventions: PROCEDURE: PEC I/II blocks by anesthesiologist - pre-operative|PROCEDURE: PEC I/II blocks by surgeon - intra-operative
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Complex Problem Solving Training in Schizophrenic Patients
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder
Interventions: BEHAVIORAL: Complex Problem Solving Training|BEHAVIORAL: Basic Cognitive Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dual-Task Training With Different Priority Instructional Sets on the Gait Parameters in Patients With Chronic Stroke
Status: COMPLETED
Conditions: Stroke|Middle Cerebral Artery Stroke|Chronic Stroke
Interventions: BEHAVIORAL: Dual-task Training Fixed Priority|BEHAVIORAL: Dual-task Training Variable Priority
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Examining the Impact of Heated Yoga on Mindfulness and Rumination
Status: NOT_YET_RECRUITING
Conditions: Depression
Interventions: BEHAVIORAL: Heated Yoga|BEHAVIORAL: Non-Heated Yoga
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Oxycodone and Sufentanil for Analgesia in Hip Surgery
Status: ENROLLING_BY_INVITATION
Conditions: Analgesia, Patient-Controlled
Interventions: DRUG: Oxycodone Hydrochloride|DRUG: Sufentanil Citrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Muscle Stretching - the Potential Role of Endogenous Pain Inhibitory Modulation on Stretch Tolerance
Status: COMPLETED
Conditions: Muscle Stretching Exercises|Pain Threshold
Interventions: OTHER: Cold pressor test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: ZD6474 Alone or in Combination With Paclitaxel and Carboplatin in Subjects With Previously Untreated Locally Advanced or Metastatic Non-small Cell Lung Cancer (NSCLC)
Status: COMPLETED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: ZD6474|DRUG: Paclitaxel|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Therapist-dependent Dose of Spinal TENS
Status: UNKNOWN
Conditions: Transcutaneous Electrical Nerve Stimulation|Spinal Cord Stimulation|Dose-response Relationship
Interventions: DEVICE: Spinal TENS|DEVICE: Sham stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Customized Lateral Nasal Wall Osteotomy on the Pterygomaxillary Separation During le Fort I Down-fracture
Status: COMPLETED
Conditions: Malocclusion|Open Bite|Le Fort; I|Orthognathic Surgery
Interventions: PROCEDURE: orthogantic surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study to Learn How the Study Medicine Called PF-07275315 Works in Healthy People
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: PF-07275315|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Phase 2 Study With Gemcitabine Alone and Combination Therapy for Patients With Advanced Biliary Tract Cancer
Status: COMPLETED
Conditions: Biliary Tract Cancer
Interventions: DRUG: gemcitabine|DRUG: cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: S1013: Validation of Cancer Questionnaire for Skin Toxicities in Patients With Colorectal Cancer or Lung Cancer Receiving Cetuximab, Panitumumab, or Erlotinib Hydrochloride
Status: COMPLETED
Conditions: Colorectal Cancer|Dermatologic Complications|Lung Cancer|Therapy-related Toxicity
Interventions: PROCEDURE: assessment of therapy complications|PROCEDURE: psychosocial assessment and care|PROCEDURE: quality-of-life assessment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p