pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Study of Extended-Release Hydrocodone/Acetaminophen (Vicodin CR®) in Subjects With Acute Pain Following Bunionectomy
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Hydrocodone/Acetaminophen Extended-Release|DRUG: Hydrocodone/Acetaminophen Extended Release|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Surufatinib Combined With KN046 and AG Regimen Chemotherapy as First-Line Treatment for Unresectable Advanced Pancreatic Cancer
Status: RECRUITING
Conditions: Unresectable Locally Advanced or Metastatic Pancreatic Cancer
Interventions: DRUG: surufatinib|DRUG: KN046|DRUG: gemcitabine|DRUG: Nab paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Establishing Functional Biomarkers for Spaced Theta-Burst Stimulation
Status: TERMINATED
Conditions: Healthy Volunteers
Interventions: DEVICE: continuous Theta Burst Stimulation|DEVICE: intermittent Theta Burst Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Prospective Trial to Study the Evolution of Clonal Architecture of Tumors From Patients Treated With Molecular Targeted Agents
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Oncogen-driven Cancer
Interventions: PROCEDURE: Biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: SAL067 Treatment in Patients With Type 2 Diabetes Who Are Not Controlled With Diet and Exercise
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: SAL067|DRUG: Alogliptin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: COSMED K5 Validation and Reliability Study
Status: RECRUITING
Conditions: Cardiopulmonary|Exercise
Interventions: DEVICE: COSMED K5 CPET (Cardiopulmonary Exercise Test)|DEVICE: ParvoMedics CPET
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study to Evaluate Safety and PK of CHS-006 in Combination With Toripalimab in Patients With Advanced Solid Tumors
Status: TERMINATED
Conditions: Advanced Solid Tumor|Non-Small Cell Lung Cancer|Hepatocellular Carcinoma
Interventions: DRUG: CHS-006 (anti-TIGIT)|DRUG: toripalimab (anti-PD-1)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Outcomes of IVUS-guided Stenting Using the Boston Scientific Vici® Venous Stent System in Treating Patients With Chronic Non-malignant Iliofemoral Vein Obstruction
Status: WITHDRAWN
Conditions: Chronic Venous Disorder|Venous Outflow Obstruction|Systemic Vein Outflow of Iliofemoral Vein
Interventions: DEVICE: Boston Scientific Vici® Venous Stent System|DEVICE: Boston Scientific Opticross 35 Peripheral Imaging Catheter (OC35 catheter)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Honey, as a Dietary Supplement in Children With Hepatitis A
Status: COMPLETED
Conditions: Hepatitis A
Interventions: DIETARY_SUPPLEMENT: honey|DIETARY_SUPPLEMENT: molasses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase III Study Evaluating the Efficacy and Safety of Crovalimab Versus Eculizumab in Participants With Paroxysmal Nocturnal Hemoglobinuria (PNH) Not Previously Treated With Complement Inhibitors.
Status: ACTIVE_NOT_RECRUITING
Conditions: Paroxysmal Nocturnal Hemoglobinuria
Interventions: DRUG: Crovalimab|DRUG: Eculizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing the Effectiveness of Oral Versus Intravenous Pain Medicine for Suction Curettage (D&C)
Status: TERMINATED
Conditions: Undesired Pregnancy
Interventions: DRUG: oxycodone + lorazepam versus fentanyl + midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The EVARREST® Paediatric Mild/Moderate Liver and Soft Tissue Bleeding Study
Status: COMPLETED
Conditions: Hemorrhage|Soft Tissue Bleeding|Hepatic Parenchyma Bleeding
Interventions: BIOLOGICAL: EVARREST™ Sealant Matrix|DEVICE: SURGICEL®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Camrelizumab Combined With Trastuzumab and Chemotherapy in Patients With HER2-positive Advanced Colorectal Cancer
Status: NOT_YET_RECRUITING
Conditions: Colorectal Neoplasms|Intestinal Neoplasms
Interventions: DRUG: Camrelizumab|DRUG: Trastuzumab|DRUG: XELOX regimen|DRUG: mFOLFOX6 regimen|DRUG: FOLFIRI regimen|DRUG: mXELIRI regimen|DRUG: mIRIS regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility Study of Vessel Analysis for Noninvasive Diagnosis of Malignancy in Breast Tumors
Status: TERMINATED
Conditions: Breast Cancer
Interventions: OTHER: Magnetic Resonance Angiography (MRA) of the Breast
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Experimentation of a Personalized Physical Self-education Program at Home: Feasibility Study (PROSOL TELEKINECT)
Status: WITHDRAWN
Conditions: Neuromuscular Diseases|Neurodegenerative Diseases
Interventions: PROCEDURE: Feasability of a personalised physical rehabilitation program at home
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Sternal Intraosseous Transfusion of Autologous Whole Blood: A Comparison of Flow Rates and Degree of Hemolysis
Status: COMPLETED
Conditions: Hypovolemic Shock|Hemorrhagic Shock
Interventions: DEVICE: Reinfusion - Sternal IO needle|DEVICE: Reinfusion - Intravenous needle
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Comparative Evaluation of a MPS Dressing and a CMC Dressing on Subjects With Lower Extremity Venous Ulcers
Status: TERMINATED
Conditions: Venous Leg Ulcer
Interventions: DEVICE: Marine polysaccharide dressing|DEVICE: Carboxymethylcellulose dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Real-World Study on Distal Aortic Remodeling for Stanford Type B Aortic Dissection With Fabulous Thoracic Aortic Stent System
Status: NOT_YET_RECRUITING
Conditions: Aortic Dissection
Interventions: DEVICE: Fabulous Thoracic Aortic Stent System
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Myofascial Release With Isometric Exercises Versus Scapular Stabilization Exercise on Neck Pain in Text Neck
Status: COMPLETED
Conditions: Neck Pain
Interventions: OTHER: Myofascial release with isometric exercises|OTHER: Myofascial release with scapular stabilization exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Dalantercept in Patients With Squamous Cell Carcinoma of the Head and Neck
Status: COMPLETED
Conditions: Squamous Cell Carcinoma of the Head and Neck
Interventions: BIOLOGICAL: Dalantercept
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase Ib Study of Belinostat With RDHAP Chemotherapy (Dexamethasone, Cytarabine, Cisplatinum) in Adults With Relapsed or Refractory Diffuse Large B-cell Lymphoma
Status: WITHDRAWN
Conditions: Lymphoma
Interventions: DRUG: Belinostat|DRUG: Rituximab|DRUG: Cisplatin|DRUG: Cytarabine|DRUG: Dexamethasone|DRUG: Ciprofloxacin|DRUG: Fluconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Daclatasvir (BMS-790052) and Simeprevir (TMC435) in Patients With Genotype 1 Chronic Hepatitis C Virus
Status: COMPLETED
Conditions: Hepatitis C Virus
Interventions: DRUG: Daclatasvir|DRUG: Simeprevir|DRUG: Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reliability and Validity of Strength Measurement of the Lower Limbs in Typically Developing Children
Status: COMPLETED
Conditions: Children|Muscle Strength|Reproducibility of Results|Muscle Strength Dynamometer|Knee
Interventions: DEVICE: Biodex System 4
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Lean Pork Loin Intake on Protein Homeostasis and Glucose Regulation in Prediabetic Adults
Status: RECRUITING
Conditions: PreDiabetes|Hyperglycaemia (Non Diabetic)
Interventions: OTHER: Lean Pork vs Plant Based
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Effect of Fish Oils on Human Hepatic Colorectal Metastases
Status: COMPLETED
Conditions: Colorectal Liver Metastases
Interventions: DIETARY_SUPPLEMENT: Lipidem- fish oil emulsion BBraun UK|PROCEDURE: Digital Contrast MRI scan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy Plus Bone Marrow or Peripheral Stem Cell Transplantation in Treating Patients With Myeloproliferative Disorders
Status: COMPLETED
Conditions: Chronic Myeloproliferative Disorders|Leukemia|Myelodysplastic/Myeloproliferative Diseases
Interventions: DRUG: busulfan|DRUG: cyclophosphamide|DRUG: cyclosporine|DRUG: methotrexate|DRUG: tacrolimus|PROCEDURE: allogeneic bone marrow transplantation|PROCEDURE: peripheral blood stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: A Study of T3011 Administered Via Intratumoral Injection in Patients With Advanced Solid Tumors
Status: RECRUITING
Conditions: Advanced Solid Tumor|Sarcoma|HNSCC|Breast Cancer|Esophagus Cancer|NSCLC|Non-melanoma Skin Cancer
Interventions: BIOLOGICAL: T3011|BIOLOGICAL: T3011|BIOLOGICAL: T3011|BIOLOGICAL: T3011|BIOLOGICAL: T3011|BIOLOGICAL: T3011|BIOLOGICAL: T3011
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Safety and Effectiveness of ARTIA Reconstructive Tissue Matrix Breast Reconstruction (ADORA) in Adult Participants
Status: NOT_YET_RECRUITING
Conditions: Breast Reconstruction
Interventions: DEVICE: ARTIA Reconstructive Tissue Matrix|OTHER: No Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Clinical Study on a Low-power Electromagnetic Wave Breast Imaging Device for Cancer Screening Purposes.
Status: COMPLETED
Conditions: Breast Cancer|Breast Cyst
Interventions: DEVICE: Low-power microwave breast imaging system
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Use of Socially Assistive Robots for Long Term Care Older Adults With Cognitive Impairment and Apathy
Status: RECRUITING
Conditions: Alzheimer Disease
Interventions: BEHAVIORAL: Socially Assistive Robot Activity
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rhodiola Rosea for Mental and Physical Fatigue
Status: UNKNOWN
Conditions: Fatigue
Interventions: DIETARY_SUPPLEMENT: Rhodiola rosea
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Mode of Action of a Single Dose and Multiple Doses of Long Acting Activated Recombinant Human Factor VII in Patients With Haemophilia A and B
Status: COMPLETED
Conditions: Congenital Bleeding Disorder|Haemophilia A|Haemophilia B
Interventions: DRUG: activated recombinant human factor VII, long acting|DRUG: activated recombinant human factor VII, long acting
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Consumer Evaluation of Intermittent Catheter Product Modifications
Status: COMPLETED
Conditions: Urinary Incontinence
Interventions: DEVICE: Currently marketed Hydrophillic Intermittent Catheter|DEVICE: Test Hydrophilic Intermittent Catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: An Open Label Study to Evaluate the Safety and Efficacy of BOR15001L7 for the Treatment of Cold Sores in Patients With Recurrent Herpes Labialis
Status: UNKNOWN
Conditions: Recurrent Herpes Labialis
Interventions: DRUG: BOR15001L7|DRUG: Docosanol Cream 10%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Intervention and Prevention of Non-Alcoholic Fatty Liver Disease in Adolescents
Status: COMPLETED
Conditions: Non-alcoholic Fatty Liver Disease
Interventions: BEHAVIORAL: Experimental: Low-fructose, reduced carbohydrate diet|BEHAVIORAL: General Healthy Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Is Acupoints Sensation Necessary for Acu-TENS to Elicit Physiological Changes in Healthy Subjects?
Status: UNKNOWN
Conditions: Autonomic Nervous System Disorder
Interventions: OTHER: Acu-TENS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Strategy of Early Detection and Active Management of Supraventricular Arrhythmia With Telecardiology (SETAM)
Status: COMPLETED
Conditions: Atrial Fibrillation|Atrial Flutter|Atrial Tachycardia
Interventions: OTHER: Telecardiology
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of a Combination of Plant Extracts (BSL_EP028) on Joint Mobility
Status: UNKNOWN
Conditions: Joint Diseases
Interventions: COMBINATION_PRODUCT: Combination of plant extracts (BSL_EP028)|COMBINATION_PRODUCT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: European Blood Pressure Intensive Control After Stroke
Status: RECRUITING
Conditions: Ischemic Stroke|Transient Ischemic Attack
Interventions: OTHER: anti-hypertensive, home blood pressure measurement, telemonitoring and medication titration|OTHER: Standard of Care Blood Pressure Management with Antihypertensives
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Tildrakizumab in Treatment of Bullous Pemphigoid
Status: UNKNOWN
Conditions: Pemphigoid, Bullous
Interventions: DRUG: Tildrakizumab Prefilled Syringe
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Novel Anti-Obesity Drug Combination as a Pharmacotherapy for Cocaine Dependence
Status: COMPLETED
Conditions: Cocaine Use Disorders
Interventions: DRUG: Bupropion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Non-invasive Biomarker Discovery for Pre-cervical or/and Cervical Cancer-HPV DNA and Other Biomarkers in Urine
Status: RECRUITING
Conditions: Cervical Cancer
Interventions: DIAGNOSTIC_TEST: Collect HPV DNA from urine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Efficacy and Safety of Melatonin PR and Clonazepam in Patients With REM Sleep Behavior Disorder in Parkinson Disease
Status: UNKNOWN
Conditions: REM Sleep Behavior Disorder|Parkinson Disease
Interventions: DRUG: Melatonin PR|DRUG: Clonazepam|DRUG: Melatonin PR placebo|DRUG: Clonazepam placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Exploring Use of Internet-Delivered Cognitive Behaviour Therapy (ICBT) by Diverse Ethnocultural People of Saskatchewan
Status: COMPLETED
Conditions: Anxiety|Depression
Interventions: BEHAVIORAL: Internet-delivered Cognitive Behavioural Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Zespri Green Kiwifruit on Digestive and Gut Health Functions
Status: COMPLETED
Conditions: Irritable Bowel Syndrome
Interventions: OTHER: Kiwifruit|DIETARY_SUPPLEMENT: Psyllium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intraperitoneal Versus Intravenous Dexmedetomidine for Post-operative Analgesia Following Laparoscopic Sleeve Gastrectomy Surgery
Status: COMPLETED
Conditions: Postoperative Pain After Laparoscopic Sleeve Gastrectomy
Interventions: PROCEDURE: intraperitoneal local anaesthetic instillation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy of Zoledronic Acid + Colaren vs Zoledronic Acid + Conventional Treatment for Osteoporosis in HIV+ and HIV- Men
Status: COMPLETED
Conditions: Secondary Osteoporosis
Interventions: DRUG: Colaren in HIV positive|DRUG: standard treatment in HIV positive|DRUG: Colaren in HIV negative|DRUG: standard treatment in HIV negative
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Endonasal Dacryocystorhinostomy With and Without Silicone Tubes
Status: COMPLETED
Conditions: Nasolacrimal Duct Obstruction
Interventions: PROCEDURE: Endonasal dacryocystorhinostomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Study of Apremilast (CC-10004) in Adults With in Psoriatic Arthritis
Status: COMPLETED
Conditions: Psoriatic Arthritis
Interventions: DRUG: Apremilast|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: UVA Islet Cell Transplantation in Patients With Type I Diabetes
Status: UNKNOWN
Conditions: Diabetes Mellitus, Type 1
Interventions: PROCEDURE: Pancreatic Islets of Langerhans Cell Transplant
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preliminary Evaluation of Septin9 in Patients With Hereditary Colon Cancer Syndromes
Status: COMPLETED
Conditions: Familial Adenomatous Polyposis|Map Syndrome|Lynch Syndrome|Hnpcc|Colorectal Cancer
Interventions: OTHER: Epi proColon Testing
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Trial on Efficacy and Safety of Pritelivir Ointment for Treatment of Labial Herpes
Status: COMPLETED
Conditions: Herpes Labialis
Interventions: DRUG: Pritelivir 5% w/w ointment|DRUG: Pritelivir ointment matching placebo|DRUG: Zovirax® cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Vitamin K Supplementation for Calcific Uremic Arteriolopathy
Status: COMPLETED
Conditions: Calciphylaxis|Calcific Uremic Arteriolopathy
Interventions: DIETARY_SUPPLEMENT: Vitamin K|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Application of Brachial Plexus Block in Patients Undergoing Cerebral Aneurysm Embolization Via Transradial Approach
Status: RECRUITING
Conditions: Intracranial Aneurysm|Transradial Access(TRA)
Interventions: DRUG: Ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of VRGs on Changing the Center of Gravity Location in AIS
Status: COMPLETED
Conditions: Adolescent Idiopathic Scoliosis
Interventions: OTHER: Virtual Reality Games|OTHER: Waiting List
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Embeda (Kadian NT, ALO-01) in Subjects With Pain Due to Osteoarthritis of the Hip or Knee
Status: COMPLETED
Conditions: Osteoarthritis|Chronic Pain
Interventions: DRUG: ALO-01 (Morphine Sulfate Plus Naltrexone Hydrochloride Extended Release)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Pemetrexed in Recurrent Cervical Adenocarcinomas
Status: TERMINATED
Conditions: Adenocarcinoma of the Cervix|Adenosquamous Cell Carcinoma of the Cervix
Interventions: DRUG: Pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oblimersen and Imatinib Mesylate in Treating Patients With Chronic Myelogenous Leukemia
Status: COMPLETED
Conditions: Chronic Myelogenous Leukemia, BCR-ABL1 Positive|Chronic Phase Chronic Myelogenous Leukemia|Relapsing Chronic Myelogenous Leukemia
Interventions: BIOLOGICAL: oblimersen sodium|DRUG: imatinib mesylate|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Roflumilast Plus Montelukast in Adults With Severe Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Roflumilast|DRUG: Roflumilast placebo|DRUG: Montelukast
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Pooled Analysis of the HGS1006-C1056 (BLISS-52) and HGS1006-C1057 (BLISS-76) Studies
Status: COMPLETED
Conditions: Lupus Erythematosus, Discoid
Interventions: DRUG: Belimumab 1 mg/kg|DRUG: Belimumab 10 mg/kg|OTHER: Placebo
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Efficacy of 9MW0813 in Subjects With Diabetic Macular Edema
Status: COMPLETED
Conditions: Diabetic Macular Edema
Interventions: DRUG: 9MW0813|DRUG: Aflibercept
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Menopausal Hormone Therapy on Immune System Parameters
Status: COMPLETED
Conditions: Last Period Not Earlier Than 6 Months Ago
Interventions: DRUG: oral menopausal hormone therapy|DRUG: transdermal menopausal hormone therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Virological and Immunological Monitoring in Patients (Suspected of/Confirmed With) COVID-19
Status: ACTIVE_NOT_RECRUITING
Conditions: COVID-19
Interventions: PROCEDURE: Blood draw|PROCEDURE: Bronchoalveolar lavage|PROCEDURE: SARS CoV-2 swabs
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Reduced-Intensity Hematopoietic Stem Cell Transplant for High Risk Lysosomal and Peroxisomal Disorders
Status: COMPLETED
Conditions: Lysosomal Storage Disease|Peroxisomal Disorder
Interventions: DRUG: Campath-1H|DRUG: Clofarabine|DRUG: Melphalan|RADIATION: Total Body Irradiation with Marrow Boosting|BIOLOGICAL: Hematopoietic stem cell transplantation|DRUG: Cyclosporine A|DRUG: Mycophenolate mofetil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pecto-Intercostal Fascial Block vs. Transversus Thoracic Muscle Plane Block in Cardiac Surgery
Status: COMPLETED
Conditions: Pain, Postoperative|Coronary Artery Disease
Interventions: PROCEDURE: Single-injection, ultrasound-guided bilateral PIF block.|PROCEDURE: Single-injection, ultrasound-guided bilateral TTMP block.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Furosemide as Supportive Therapy for COVID-19 Respiratory Failure
Status: TERMINATED
Conditions: Covid19|Respiratory Failure
Interventions: DRUG: Nebulized Furosemide|DRUG: Nebulized Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Stromal Vascular Fraction (SVF) for Treatment of Recto-vaginal Fistula
Status: UNKNOWN
Conditions: Recto-vaginal Fistula
Interventions: DRUG: Adipose-derived stem cells without expanded
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TSTstarr + for Treatment of Severe Prolapsed Hemorrhoids --- a Multi-center Randomized Controlled Clinical Trail
Status: UNKNOWN
Conditions: Hemorrhoids
Interventions: PROCEDURE: TSTstarr+|PROCEDURE: PPH
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Azilsartan Tablets in Chinese Healthy Volunteers
Status: COMPLETED
Conditions: Bioequivalence of Two Azilsartan Formulations
Interventions: DRUG: Azilsartan (Zhaoke)|DRUG: Azilsartan (Takeda)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Blood Flow Restriction (BFR) Therapy on ACL Graft Maturation
Status: RECRUITING
Conditions: Knee Injuries|Anterior Cruciate Ligament Injuries
Interventions: OTHER: Blood Flow Restriction Therapy|OTHER: Standard Postoperative Physical Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Etanercept in New Onset Type 1 Diabetes
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: DRUG: Etanercept|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy Plus PD-1 Monoclonal Antibody in the Treatment of Refractory or Relapsed Peripheral T-cell Lymphoma.
Status: RECRUITING
Conditions: Peripheral T-Cell Lymphoma, Not Otherwise Specified|Angioimmunoblastic T-cell Lymphoma
Interventions: DRUG: Rituximab|DRUG: Gemcitabine|DRUG: Dexamethasone|DRUG: Cisplatin|DRUG: PD-1 monoclonal antibody
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Dosing and Environment on Gross Motor and Spasticity in Spastic Quadriplegic
Status: COMPLETED
Conditions: Spastic Cerebral Palsy
Interventions: OTHER: Enriched Environment|OTHER: Traditional Physcial Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Efficacy and Safety of DWJ211 in Patient With Moderate or Severe Submental Fat
Status: COMPLETED
Conditions: Submental Fat
Interventions: DRUG: Normal saline|DRUG: DWJ211
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Obstructive Sleep Apnea (OSA) and Metabolic Syndrome: Role of Oxidative Stress
Status: UNKNOWN
Conditions: Obstructive Sleep Apnea|Metabolic Syndrome X
Interventions: PROCEDURE: sleep disruption|PROCEDURE: sleep with and without positive pressure
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Single Ascending Dose Study of NH102 in Healthy Subjects
Status: UNKNOWN
Conditions: Depression
Interventions: DRUG: NH102|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Crowding Without Extraction Using Self Ligating Brackets
Status: COMPLETED
Conditions: Crowding
Interventions: DEVICE: Traditional brackets|DEVICE: Active self-ligating brackets|DEVICE: Passive self-ligating brackets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Role of Natriuretic Peptides in the Treatment of Acutely Decompensated Heart Failure Patient With Obstructive Airways Disease
Status: TERMINATED
Conditions: Heart Failure
Interventions: DRUG: Nesiritide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of a 12-week Respiratory Muscles Training Program in Persons With Relapsing- Remitting Multiple Sclerosis
Status: UNKNOWN
Conditions: Relapsing-remitting Multiple Sclerosis
Interventions: OTHER: a 12-week Respiratory Muscles Training Program (RMTP)|OTHER: Active Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Extension Study of P1101 After Completion of Phase 2 Study in PV Patients or Phase 3 Study in ET Patients
Status: RECRUITING
Conditions: Polycythemia Vera (PV)
Interventions: BIOLOGICAL: P1101 (Ropeginterferon alfa-2b)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 26 Week Efficacy and Safety Trial for Patients With Chronic Idiopathic Constipation
Status: TERMINATED
Conditions: Chronic Idiopathic Constipation
Interventions: DRUG: Elobixibat 10 mg|DRUG: Elobixibat 5 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: To Study the Efficacy and Safety of Renessans in Chronic HCV Patients
Status: UNKNOWN
Conditions: Hepatitis C, Chronic
Interventions: BIOLOGICAL: RENESSANS , INTERFERON ALPHA 2b, Ribavirin|DRUG: Interferon Alfa-2b AND RIBAVIRIN|BIOLOGICAL: RENESSANS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diabetes Learning in Virtual Environments Just in Time for Community Reentry
Status: RECRUITING
Conditions: Diabetes Mellitus, Type 1|Diabetes Mellitus, Type 2
Interventions: OTHER: Diabetes LIVE JustICE|OTHER: Enhanced Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of LY2940680 in Small Cell Lung Cancer
Status: TERMINATED
Conditions: Small Cell Lung Carcinoma
Interventions: DRUG: LY2940680|DRUG: Carboplatin|DRUG: Etoposide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Early Mobilisation in Intensive Care Unit : Interest of Cyclo-ergometry in Patients With Septic Chock
Status: TERMINATED
Conditions: Sepsis
Interventions: DEVICE: Early mobilisation with cyclo ergometer|OTHER: Standard physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PROOF-OF-CONCEPT STUDY FOR NEW INTRAOCULAR LENS, MODEL C0002
Status: RECRUITING
Conditions: Cataracts
Interventions: DEVICE: Model C0002|DEVICE: Model ZCB00/DCB00
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Montelukast and Its Effect on Lower Leg Growth in Children With Asthma (MK-0476-254)
Status: COMPLETED
Conditions: Asthma, Bronchial
Interventions: DRUG: Montelukast chewable tablets|DRUG: Budesonide inhaler|DRUG: Placebo to montelukast chewable tablets|DRUG: Placebo to budesonide inhaler
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An Open-label, Dose Escalation Study in Japanese Participants With Relapsed/Refractory Multiple Myeloma Who Have Failed Prior Anti Myeloma Treatments
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: Belantamab mafodotin|DRUG: Bortezomib|DRUG: Dexamethasone|DRUG: Pomalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preoperative Bevacizumab and Trastuzumab With ABI-007 and Carboplatin in HER2+ Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: nab-paclitaxel|DRUG: Bevacizumab|DRUG: Trastuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacists' Interventions to Improve Blood Pressure in Chronic Kidney Disease
Status: COMPLETED
Conditions: Chronic Kidney Diseases
Interventions: DEVICE: Digital BP monitor (Chidalex®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Safety and Efficacy of NAFT900 in Children With Tinea Capitis
Status: WITHDRAWN
Conditions: Tinea Capitis
Interventions: DRUG: Naftifine hydrochloride foam, 3%|DRUG: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Statins to Reduce D-dimer Levels in Patients With Venous Thrombosis
Status: TERMINATED
Conditions: Venous Thromboembolism|Hypercholesterolemia
Interventions: DRUG: atorvastatin|DRUG: atorvastatin|BEHAVIORAL: diet|BEHAVIORAL: diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 17-AAG in Treating Patients With Metastatic Prostate Cancer That Did Not Respond to Previous Hormone Therapy
Status: COMPLETED
Conditions: Adenocarcinoma of the Prostate|Recurrent Prostate Cancer|Stage IV Prostate Cancer
Interventions: DRUG: tanespimycin|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aminocamptothecin in Treating Patients With Stomach Cancer or Cancer of the Esophagus
Status: COMPLETED
Conditions: Esophageal Cancer|Gastric Cancer
Interventions: DRUG: aminocamptothecin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: a Novel Individualized Substrate Modification Approach for the Treatment of Long-standing Persistent Atrial Fibrillation
Status: UNKNOWN
Conditions: Atrial Fibrillation
Interventions: PROCEDURE: individualized substrate modification|PROCEDURE: stepwise ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerance Study of Alpha-Lactalbumin Enriched and Probiotic-Supplemented Infant Formula in Infants With Colic
Status: COMPLETED
Conditions: Growth|Colic
Interventions: OTHER: Modilac Dahlia 1|OTHER: Modilac 1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Carboplatin and Gemcitabine Hydrochloride With or Without Vandetanib as First-Line Therapy in Treating Patients With Locally Advanced or Metastatic Urinary Tract Cancer
Status: COMPLETED
Conditions: Bladder Cancer|Transitional Cell Cancer of the Renal Pelvis and Ureter|Ureter Cancer|Urethral Cancer
Interventions: DRUG: carboplatin|DRUG: gemcitabine hydrochloride|DRUG: vandetanib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Video Use on Quality of Discharge Teaching and Patient Satisfaction in Day Surgery Patients
Status: ENROLLING_BY_INVITATION
Conditions: Patient Satisfaction|Quality of Care
Interventions: BEHAVIORAL: video assisted discharge teaching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Comparing the Outcome in Patients of Acute Pancreatitis, With and Without Prophylactic Antibiotics
Status: COMPLETED
Conditions: Acute Pancreatitis
Interventions: DRUG: Meropenem
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of a Desensitizing Agent During At-home Bleaching
Status: COMPLETED
Conditions: Sensitivity, Tooth
Interventions: DRUG: UltraEZ|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Anti Inflammatory Effects of Local Cryotherapy in Knee Arthritis
Status: COMPLETED
Conditions: Arthritis Knee|Cryotherapy Effect
Interventions: DEVICE: cryotherapy (Thermogel - Artsana or Cryo+ - Cryonic)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Role of VAC Therapy Devices in Promoting Closure of Enterocutaneous Fistulae
Status: WITHDRAWN
Conditions: Fistulae
Interventions: DEVICE: V.A.C.Ulta™ Negative Pressure Wound Therapy System|PROCEDURE: Vac sponge irrigations|PROCEDURE: ostomy bag|PROCEDURE: wet to dry dressings
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: TOTEM: Switch From Other Nucleoside Reverse Transcriptase Inhibitors (NRTIs) to Once Daily Truvada
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Truvada|DRUG: Current HAART regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: LCS12 vs Combined Oral Contraceptive (COC) User Satisfaction Study
Status: COMPLETED
Conditions: Contraception
Interventions: DRUG: Levonorgestrel IUD (LCS, BAY86-5028)|DRUG: Yasmin (EE30/DRSP, BAY86-5131)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Tislelizumab in Combination With TACE in Advanced Hepatocellular Carcinoma
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Tislelizumab in combination with cTACE
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fractional Flow Reserve and Instantaneous Free-wave Ratio Revascularization Strategies in Women
Status: ENROLLING_BY_INVITATION
Conditions: Coronary Disease|Percutaneous Coronary Intervention|Exercise Test|Myocardial Perfusion Imaging|Cardiac Catheterization
Interventions: OTHER: No study intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Bortezomib and Dexamethasone With or Without Lenalidomide in Treating Patients With Multiple Myeloma Previously Treated With Dexamethasone
Status: TERMINATED
Conditions: Stage I Multiple Myeloma|Stage II Multiple Myeloma|Stage III Multiple Myeloma
Interventions: DRUG: bortezomib|DRUG: lenalidomide|DRUG: dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Volatile Organic Compounds in Exhaled Air and Sweat of Patients Treated by Immunotherapy for Lung Cancer: Research on Biomarkers for Early Therapeutic Response
Status: TERMINATED
Conditions: Lung Cancer, Non-small Cell
Interventions: DEVICE: VOC analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: BioFreedom Pharmacokinetic Study
Status: COMPLETED
Conditions: Coronary Artery Disease|Myocardial Infarction
Interventions: DEVICE: BioFreedom™ BA9™ drug-coated stent
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low-Dose Dobutamine and Single-Dose Tocilizumab in Acute Myocardial Infarction With High Risk of Cardiogenic Shock
Status: RECRUITING
Conditions: Acute Myocardial Infarction|Cardiogenic Shock
Interventions: DRUG: Tocilizumab|DRUG: Dobutamine|DRUG: NaCl 0.9%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of Vardenafil and Carboplatin in Patients With Gliomas and Brain Metastases
Status: TERMINATED
Conditions: Glioma|Brain Neoplasms|Brain Metastasis
Interventions: DRUG: Vardenafil|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasound Guided Transversus Abdominis Plane (TAP) Block for Postoperative Analgesia After Laparoscopic Colonic Resection
Status: COMPLETED
Conditions: Laparoscopic Colecctomy
Interventions: PROCEDURE: Ultrasound Guided Transversus Abdominis Plane (TAP) Block|DRUG: bupivacaine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Cardiovascular Benefits of Resistance, Aerobic, and Combined Exercise
Status: COMPLETED
Conditions: Cardiovascular Diseases
Interventions: BEHAVIORAL: aerobic exercise|BEHAVIORAL: resistance exercise|BEHAVIORAL: Combined resistance and aerobic exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Gut Microbial Metabolites of Apple Polyphenols
Status: RECRUITING
Conditions: Healthy|Controlled Feeding Trial
Interventions: OTHER: Dietary intervention - apple catechin diet|OTHER: Dietary intervention - low catechin diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Consumption of Chaya on Lipid Concentration and Antioxidant Status of Patients With Dyslipidemia
Status: COMPLETED
Conditions: Dyslipidemias
Interventions: DIETARY_SUPPLEMENT: Chaya (Cnidoscolus chayamansa)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Endoscopic Optical Imaging for Precision Oncology Treatment Applied to Colorectal Tumours (Elios-Color-on-Specimen)
Status: WITHDRAWN
Conditions: Colorectal Cancer
Interventions: OTHER: Characterization of tumor tissue by fluorescence
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Treatment of Insomnia in Symptomatic Peri- and Postmenopausal Women
Status: COMPLETED
Conditions: Menopause|Insomnia
Interventions: DRUG: Eszopiclone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Pain Relief After Hip Fracture Surgery: Hip and Groin Nerve Block
Status: RECRUITING
Conditions: Opioid Use|Pain, Postoperative|Hip Fractures
Interventions: PROCEDURE: Pericapsular Nerve Block (PENG)|PROCEDURE: Suprainguinal Fascia Iliaca Compartment Block (SFICB)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation by HR-pQCT of Bone Microarchitecture Changes in Patients With Rheumatoid Arthritis Under Anti-TNF Therapy.
Status: TERMINATED
Conditions: Rheumatoid Arthritis
Interventions: DEVICE: HR-pQCT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Monitoring of Adequate Course of General Anesthesia
Status: COMPLETED
Conditions: Monitoring of Depth of Anesthesia|AAI Index
Interventions: OTHER: monitoring of the proper level of general anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION