pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Treatment of Urinary Incontinence in Women With Spinal Cord Injury
Status: COMPLETED
Conditions: Spinal Cord Injury|Urinary Incontinence
Interventions: BEHAVIORAL: Pelvic floor muscle training|BEHAVIORAL: Pelvic floor muscle training|DRUG: vaginal electrical stimulator (CefarPeristim Pro)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: L-Arginine Supplementation With or Without Enzyme Inhibitors Treating Erectile Function of Prostate Cancer Survivors
Status: COMPLETED
Conditions: Male Erectile Disorder|Prostate Cancer|Radiation Toxicity
Interventions: OTHER: Placebo|DRUG: Oral L-Arginine|DRUG: Oral L-Arginine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Females, Aging, Metabolism, and Exercise
Status: COMPLETED
Conditions: Obesity
Interventions: DRUG: GnRH agonist|BEHAVIORAL: Supervised cardiovascular exercise|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of STW5 (Iberogast ®) and STW5-II (Iberogast N®) on Transit and Tolerance of Intestinal Gas
Status: COMPLETED
Conditions: Irritable Bowel Syndrome|Functional Dyspepsia
Interventions: DRUG: Iberogast® and Iberogast® N
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Sphenopalatine Ganglion Acupuncture in Patients With Seasonal Allergic Rhinitis
Status: COMPLETED
Conditions: Patients
Interventions: PROCEDURE: Sphenopalatine ganglion acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Antecedent Hypoglycemia or Exercise on the Response of the Brain to Subsequent Hypoglycemia
Status: WITHDRAWN
Conditions: Type 1 Diabetes
Interventions: PROCEDURE: Hyperinsulinemic euglycemic clamp with fMRi|PROCEDURE: Hyperinsulinemic hypoglycemic clamp study with fMRi
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Clinical Study Evaluating an Acetabular Cup System After Total Hip Replacement
Status: COMPLETED
Conditions: Osteoarthritis|Rheumatoid Arthritis|Arthritis|Avascular Necrosis|Acute Fracture
Interventions: DEVICE: Acetabular cup
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy, PEG-Interferon Alfa-2b, and Surgery in Treating Patients With Osteosarcoma
Status: COMPLETED
Conditions: Localized Osteosarcoma|Metastatic Osteosarcoma
Interventions: DRUG: Cisplatin|DRUG: Doxorubicin Hydrochloride|DRUG: Etoposide|DRUG: Ifosfamide|DRUG: Methotrexate|BIOLOGICAL: Peginterferon Alfa-2b|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration|PROCEDURE: Therapeutic Conventional Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: FLT-PET/CT vs FDG-PET/CT for Therapy Monitoring of Diffuse Large B-cell Lymphoma
Status: COMPLETED
Conditions: Lymphoma|Lymphoma, Non-Hodgkin|Large B Cell Diffuse Lymphoma
Interventions: DIAGNOSTIC_TEST: FLT-PET/CT|DIAGNOSTIC_TEST: FDG-PET/CT|DRUG: FLT
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Bioequivalence Study of 500 mg and 1000 mg Glucophage (Metformin) Tablets in Healthy Subjects
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: metformin (Diabex)|DRUG: metformin (Glucophage™)|DRUG: metformin (Glucophage™)|DRUG: metformin (Diabex)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Gemcitabine/Platinum Containing Regimens as Preoperative Chemotherapy for Patients With Non Small Cell Lung Cancer
Status: COMPLETED
Conditions: Carcinoma, Non Small Cell Lung
Interventions: DRUG: gemcitabine|DRUG: carboplatin|DRUG: cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Home-based Training and Supplementation in DM1 Patients
Status: NOT_YET_RECRUITING
Conditions: Myotonic Dystrophy 1
Interventions: DIETARY_SUPPLEMENT: Mult-ingredient supplement|DIETARY_SUPPLEMENT: Placebo|BEHAVIORAL: Concurrent exercise training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Treatments for Insomnia in Veterans With PTSD
Status: RECRUITING
Conditions: Insomnia|PTSD
Interventions: BEHAVIORAL: The ABC of Insomnia (Acceptance and the Behavioral Changes to treat Insomnia)|BEHAVIORAL: Cognitive-Behavioral Therapy for Insomnia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mirabegron as Medical Expulsive Therapy (MET) for Ureteral Stones and Ureteral Stent Pain
Status: COMPLETED
Conditions: Ureteral Obstruction|Flank Pain
Interventions: DRUG: Mirabegron|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Itch Sensation Induced by Simultaneous Application of Pruritogens (Spatial Summation)
Status: RECRUITING
Conditions: Histamine|Cowhage
Interventions: OTHER: Cowhage|OTHER: Histamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Sequential Immunization With Recombinant Adenovirus Type-5-vectored COVID-19 Vaccine in Health Adults Based on 3 Doses Inactivated COVID-19 Vaccine
Status: UNKNOWN
Conditions: Immunogenicity and Safety of a Recombinant Adenovirus Type-5-vectored COVID-19 Vaccine Using for Sequential Immunization
Interventions: BIOLOGICAL: Recombinant adenovirus type-5-vectored COVID-19 vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of an mHealth Web-Based Platform (HappyAir) on Adherence to a Maintenance Program After Pulmonary Rehabilitation in Patients With Chronic Obstructive Pulmonary Disease
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: OTHER: Pulmonary Care Web-Based App (HappyAir App)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intraoperative Low-dose Ketamine Infusion as the Main Analgesic in Burn Patients
Status: UNKNOWN
Conditions: Burns
Interventions: DRUG: Ketamine|DRUG: Sodium chloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Safety and Feasibility Study of Active Immunotherapy in Patients With Metastatic Prostate Carcinoma Using Autologous Dendritic Cells Pulsed With Antigen Encoded in Amplified Autologous Tumor RNA
Status: UNKNOWN
Conditions: Prostate Cancer
Interventions: BIOLOGICAL: Autologous dendritic cells transfected with amplified tumor RNA
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Safe and Timely Antithrombotic Removal - Ticagrelor (STAR-T)
Status: COMPLETED
Conditions: Hemorrhage, Surgical|Blood Loss, Surgical|Blood Loss, Postoperative|Hemorrhage Postoperative
Interventions: DEVICE: DrugSorb-ATR system|DEVICE: Sham comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of MRP With and Without EMS on Gait, Functional Independence and QOL in Stroke Patients
Status: RECRUITING
Conditions: Stroke
Interventions: OTHER: motor relearning programme|OTHER: electrical muscle stimulations with motor relearning programme
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ureteral Access Sheath or Percutaneous Nephrostomy During Flexible Ureteroscopy: Which is Better?
Status: NOT_YET_RECRUITING
Conditions: Flexible Ureteroscopy
Interventions: PROCEDURE: using UAS during flexible ureteroscopy and using PCN during flexible ureteroscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Automated Insulin Delivery on Early-stage Diabetic Complications
Status: UNKNOWN
Conditions: Type 1 Diabetes
Interventions: DEVICE: Medtronic MiniMed 780G with SmartGuard activation|DEVICE: Medtronic MiniMed 780G without SmartGuard activation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study in Healthy Men to Test How BI 764198 is Processed in the Body
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BI 764198 (C-14) (approach 1)|DRUG: BI 764198 (C-14) (approach 2)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigating the Potential Role of Aerosolized Retinoic Acid, a Potent Vitamin A Metabolite for Treating COVID-19 Anosmia and Retinoic Acid Insufficiency .A Novel Approach for Regaining Sense of Smell.
Status: UNKNOWN
Conditions: Post COVID-19 Anosmia (Loss of Smell)
Interventions: DRUG: Aerosolized 13 cis retinoic acid plus Vitamin D|DRUG: Aerosolized All trans retinoic acid plus Vitamin D|OTHER: Standard therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Veliparib and Pegylated Liposomal Doxorubicin Hydrochloride in Treating Patients With Recurrent Ovarian Cancer, Fallopian Tube Cancer, or Primary Peritoneal Cancer or Metastatic Breast Cancer
Status: COMPLETED
Conditions: Estrogen Receptor Negative|HER2/Neu Negative|Male Breast Carcinoma|Progesterone Receptor Negative|Recurrent Breast Carcinoma|Recurrent Fallopian Tube Carcinoma|Recurrent Ovarian Carcinoma|Recurrent Primary Peritoneal Carcinoma|Stage IV Breast Cancer AJCC v6 and v7|Triple-Negative Breast Carcinoma
Interventions: OTHER: Laboratory Biomarker Analysis|DRUG: Pegylated Liposomal Doxorubicin Hydrochloride|OTHER: Pharmacological Study|DRUG: Veliparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Minimally Invasive Total Knee Replacement - Navigated Versus Non-navigated Study
Status: TERMINATED
Conditions: Osteoarthritis
Interventions: DEVICE: Either P.F.C. Sigma or L.C.S. Complete knee replacement using the conventional surgical approach and manual surgical technique|DEVICE: Either P.F.C. Sigma or L.C.S. Complete knee replacement using minimally invasive surgical approach and computer navigation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Interaction Study SLV337/Simvastatin
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Simvastatin- SLV337 SD beta- SLV337 SD alpha - SLV337 MD beta- SLV337 SD beta+ Simvastatin|DRUG: Simvastatin - SLV337 SD alpha - SLV337 SD beta - SLV337 MD beta - SLV337 SD beta+ Simvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Methylphenidate HCl ER Capsules in Children and Adolescents With ADHD
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder|ADHD
Interventions: DRUG: Methylphenidate Hydrochloride Extended Release Capsules|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Managing Opioid Related Sleep Apnea With Acetazolamide
Status: RECRUITING
Conditions: Sleep-Disordered Breathing|Obstructive Sleep Apnea|Central Sleep Apnea|Chronic Pain|Opioid Use
Interventions: DRUG: Acetazolamide|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Obalon in Children With Severe Obesity
Status: COMPLETED
Conditions: Severe Pediatric Obesity (BMI > 97° pc -According to Centers for Disease Control and Prevention BMI Charts-)|Altered Liver Function Tests|Glycemic Intolerance
Interventions: DEVICE: Swallowable Obalon® Gastric Balloon
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cannabis' Impact on Alcohol Consumption
Status: RECRUITING
Conditions: Alcohol Drinking|Cannabis Use|Cannabis|Alcohol Use Disorder
Interventions: DRUG: THC-dominant cannabis|DRUG: CBD-dominant cannabis|DRUG: Cannabis placebo|DRUG: Alcohol|DRUG: Alcohol placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Glycaemic Index and Substrate Metabolism
Status: COMPLETED
Conditions: Substrate Metabolism During Exercise
Interventions: OTHER: Training intervention|OTHER: High Glycaemic Index|OTHER: LCHF|OTHER: Low Glycaemic Index
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Early MRI in Acute GallstonE Disease
Status: COMPLETED
Conditions: Cholecystitis; Acute, Choledocholithiasis
Interventions: DIAGNOSTIC_TEST: magnetic resonance cholangiopancreatography (MRCP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Open-label, Multicenter Immunogenicity and Safety Study of MVA-BN Vaccine in Children From 2 Years to Less Than 12 Years of Age Compared to Adults for the Prevention of Smallpox, Mpox, and Related Orthopoxvirus Infections
Status: NOT_YET_RECRUITING
Conditions: Monkeypox (Mpox)
Interventions: DRUG: MVA-BN
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Simulated Radiotherapy Treatment Assisted With Pediatric Radiation Oncology With Movie Induced Sedation Effect Technique
Status: WITHDRAWN
Conditions: Childhood Cancer
Interventions: DEVICE: AlignRT system (VisionRT LTD, UK)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Virtual Reality for Pain in Acute Orthopedic Injuries
Status: COMPLETED
Conditions: Injuries|Injury Arm|Injury;Sports|Injury, Knee|Injury Wrist|Injury, Ankle|Injury Foot|Injury, Hand|Injury Finger|Injury Leg
Interventions: DEVICE: RelieveVRx
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anlotinib Plus TQB2450 Combined With Nab-paclitaxel and Cisplatin as First-line Treatment for Advanced Biliary Tract Cancer
Status: RECRUITING
Conditions: Advanced Biliary Tract Cancer
Interventions: DRUG: anlotinib+TQB2450+nab-paclitaxel+cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Pain, Disability and Cervicokinesthesia After Cervical Manipulation
Status: COMPLETED
Conditions: Neck Pain
Interventions: OTHER: Right Cervical Manipulation|OTHER: Left Cervical Manipulation|OTHER: Sham Cervical Manipulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of the Panbio™ COVID-19/ Flu A&B Rapid Panel
Status: COMPLETED
Conditions: COVID-19|Influenza A|Influenza Type B
Interventions: DEVICE: COVID-19/ Flu A&B Rapid Panel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of the Prevalence of Complications Occurring in the Mother-newborn Couple During the First Month After Returning Home, Since the Introduction of Standard Outpatients (According to HAS 2014 Recommendations) at the Amiens-Picardie University Hospital
Status: COMPLETED
Conditions: Mother-Child Relations|Maternity
Interventions: OTHER: To study the absence of increased complications and events occurring in the "mother-newborn"
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: AZD2014 Plus Novel Anti-Cancer Agents in Relapsed or Refractory Diffuse Large B-Cell Lymphoma
Status: WITHDRAWN
Conditions: Core: Relapsed or Refractory Diffuse Large B-Cell Lymphoma|Module 1: Non-GCB Diffuse Large B-Cell Lymphoma
Interventions: DRUG: AZD2014|DRUG: Ibrutinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Brief Tailored Motivational Intervention to Prevent Early Childhood Caries
Status: COMPLETED
Conditions: Dental Caries
Interventions: BEHAVIORAL: Motivational Interviewing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study to Evaluate Sacituzumab Govitecan in Combination With Talazoparib in Patients With Metastatic Breast Cancer.
Status: RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Talazoparib|DRUG: Sacituzumab Govitecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial to Assess the Potential of LEO 130852A Gel to Reduce Steroid Induced Skin Atrophy on Healthy Skin
Status: COMPLETED
Conditions: Skin Tissue Diseases|Connective Tissue Diseases
Interventions: DRUG: Clobetasol propionate 0.05% ointment|DRUG: LEO 130852A gel 1%|DRUG: LEO 130852A placebo gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Prospective Group-Matched Study With Belzupacap Sarotalocan (Bel-sar; AU-011) or Plaque Radiotherapy for Primary Indeterminate Lesions or Choroidal Melanoma (IL/ CM)
Status: TERMINATED
Conditions: Choroidal Melanoma|Indeterminate Lesions
Interventions: OTHER: Standard of Care|DRUG: AU-011
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Acute Impact of Intramuscular (IM) Aripiprazole and Olanzapine on Insulin Resistance in High Risk Prediabetics
Status: COMPLETED
Conditions: Diabetes
Interventions: DRUG: Intramuscular olanzapine, aripiprazole|DRUG: Intramuscular aripiprazole, olanzapine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Tocilizumab for the Prevention of Graft Versus Host Disease After Cord Blood Transplantation
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Myeloid Leukemia|Acute Lymphoblastic Leukemia|Acute Leukemia|Myelodysplastic Syndromes|Myelodysplastic-Myeloproliferative Diseases|Myeloproliferative Disorder|Non Hodgkin Lymphoma|Hodgkin Lymphoma|Leukemia
Interventions: RADIATION: Total Body Irradiation|DRUG: Cyclosporine|DRUG: Mycophenolate Mofetil|DRUG: Tocilizumab|DRUG: Filgrastim
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sirolimus Drug-coated Balloon Versus Stent Graft
Status: RECRUITING
Conditions: Arteriovenous Shunt Thrombosis|Blood Vessel Prosthesis
Interventions: DEVICE: Sirolimus drug-coated balloon|DEVICE: Stent graft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Quadratus Lumborum Block in Total Hip Arthroplasty - Effect on Analgesia and Early Physiotherapy
Status: SUSPENDED
Conditions: Total Hip Arthroplasty
Interventions: PROCEDURE: anterior Quadratus Lumborum Block|PROCEDURE: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Innovative Technologies for the Treatment of Pulmonary and Heart Failure
Status: UNKNOWN
Conditions: Cardiogenic Shock|Ventricular Arrythmia|Cardiac Arrest With Successful Resuscitation|Sepsis|Multiple Organ Failure|Pulmonary Failure|Decompensated Heart Failure|Acute Heart Failure
Interventions: DEVICE: HA330 - Jafron Biomedical Co., Ltd., China - extracorporeal hemocorrection|DEVICE: CytoSorb (CytoSorbents Corp., USA) - an extracorporeal cytokine adsorber
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Captopril in Treating Patients Undergoing Bone Marrow or Stem Cell Transplantation
Status: COMPLETED
Conditions: Cancer
Interventions: DRUG: captopril|DRUG: cyclophosphamide|PROCEDURE: autologous bone marrow transplantation|PROCEDURE: peripheral blood stem cell transplantation|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of Oral Vismodegib for the Treatment of Idiopathic Pulmonary Fibrosis (IPF)
Status: WITHDRAWN
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: DRUG: placebo|DRUG: vismodegib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Medication Review in Chronic Complex or Polymedicated Patients After Hospital Discharge.
Status: RECRUITING
Conditions: Medication Review|Polypharmacy|Disease, Chronic
Interventions: BEHAVIORAL: Multidisciplinary medication review|BEHAVIORAL: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: ICBT for Psychological Symptoms Related to the COVID-19 Pandemic Remaining After Societal Opening
Status: ACTIVE_NOT_RECRUITING
Conditions: Depression Symptoms|Anxiety Symptoms
Interventions: BEHAVIORAL: Internet-based Cognitive Behavioral Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Apatinib With Oxaliplatin and S-1 Treatment for Advanced Hepatoid Adenocarcinoma Of The Stomach
Status: RECRUITING
Conditions: Gastric Cancer
Interventions: DRUG: Apatinib|DRUG: Oxaliplatin|DRUG: S1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of AG10 in Amyloid Cardiomyopathy
Status: COMPLETED
Conditions: Familial ATTR-CM (ATTRm-CM, or FAC)|Wild-type ATTR-CM (ATTRwt-CM)
Interventions: DRUG: AG10|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Work Should Not Hurt You: Reduction of Hazardous Exposures in Small Businesses Through a Community Health Worker Intervention
Status: COMPLETED
Conditions: Community Health Aides|Industrial Hygiene|Volatile Organic Compounds
Interventions: OTHER: Industrial Hygiene-Enhance Community Health Worker Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Liposomal Doxorubicin in Treating Children With Refractory Solid Tumors
Status: COMPLETED
Conditions: Childhood Soft Tissue Sarcoma|Childhood Liver Cancer|Bone Cancer|Brain Tumor|Kidney Tumor
Interventions: DRUG: doxorubicin HCl liposome
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Non-Invasive Positive Pressure Ventilation and Adult Respiratory Distress Syndrome (ARDS)
Status: COMPLETED
Conditions: Acute Respiratory Distress Syndrome
Interventions: DEVICE: the application of NPPV|DEVICE: invasive ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Anakinra to Prevent or Treat Severe Side Effects for Patients Receiving CAR-T Cell Therapy
Status: ACTIVE_NOT_RECRUITING
Conditions: B Cell ALL|B-Cell Lymphoma|B-cell Non Hodgkin Lymphoma
Interventions: DRUG: Anakinra
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vitamin K2 and Muscle Weakness in Type 2 Diabetes
Status: RECRUITING
Conditions: Diabete Type 2
Interventions: DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: Vitamin K2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Substudy of Investigational Agents in Programmed Cell Death-1/Ligand 1 (PD-1/L1) Refractory Locally Advanced or Metastatic Urothelial Carcinoma (mUC) (MK-3475-04A)
Status: ACTIVE_NOT_RECRUITING
Conditions: Urothelial Carcinoma
Interventions: BIOLOGICAL: Zilovertamab vedotin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Efficacy Study of a New Formulation of Ketoconazole 2% Cream in Patients With Tinea Pedis, Commonly Known as Athlete's Foot
Status: TERMINATED
Conditions: Tinea Pedis
Interventions: DRUG: Placebo cream|DRUG: Ketoconazole 2% cream (formulation F012) (Nizoral)|DRUG: Ketoconazole 2% cream (formulation F126)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Surgical Versus Functional Treatment for Acute Ruptures of the Lateral Ligament Complex of the Ankle in Young Males - A Randomized Controlled Trial With a Mean of 14 Years Follow-up
Status: COMPLETED
Conditions: Ankle Injury
Interventions: PROCEDURE: lateral ligament surgery|DEVICE: functional treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: NPWT in Patients Undergoing Surgical Procedures for Management of GI Malignancies
Status: RECRUITING
Conditions: Surgical Wound Infection
Interventions: DEVICE: Negative Pressure Wound Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Fenofibrate for Patients With COVID-19 Requiring Hospitalization
Status: UNKNOWN
Conditions: Corona Virus Disease (COVID-19)|Respiratory Distress Syndrome|SARS-CoV-2 Infection
Interventions: DRUG: TriCor® 145mg tablets|OTHER: Placebo|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mirtazapine Reduces ICD Shocks in ICD Patients With Depression and Anxiety
Status: COMPLETED
Conditions: Depression|Anxiety
Interventions: DRUG: mirtazapine|DRUG: mirtazapine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Glutamine to Improve Outcomes in Cardiac Surgery
Status: COMPLETED
Conditions: Nosocomial Infection
Interventions: DIETARY_SUPPLEMENT: Glutamine|DIETARY_SUPPLEMENT: Maltodextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Transcranial Direct Current Stimulation for Post-stroke Motor Recovery
Status: ACTIVE_NOT_RECRUITING
Conditions: Stroke, Ischemic|Motor Activity|Upper Extremity Paralysis
Interventions: DEVICE: Sham|DEVICE: Low dose tDCS|DEVICE: High dose tDCS|BEHAVIORAL: mCIMT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Valerian for Conscious Sedation in Patients Submitted to Impacted Lower Third Molars Surgery
Status: COMPLETED
Conditions: Dental Anxiety|Blood Pressure|Heart Rate
Interventions: DRUG: 100 mg of Valeriana officinalis L|DRUG: Placebo 100mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Totally no Tube (TNT) Uniportal Video-assisted Thoracoscopic Surgery (VATS) VS Traditional Uniportal VATS for Mediastinal Tumor
Status: COMPLETED
Conditions: Mediastinal Tumor
Interventions: PROCEDURE: TNT uniportal VATS mediastinal tumor resection|PROCEDURE: Traditional uniportal VATS mediastinal tumor resection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Use of a Device Called Impulse Oscillometry in Participants With Vocal Cord Disorders or Asthma
Status: ACTIVE_NOT_RECRUITING
Conditions: Breathing, Mouth|Lung Function Decreased|Vocal Cord Dysfunction|Laryngeal Obstruction|Asthma
Interventions: DEVICE: Impulse Oscillometer
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Intraperitoneal Bupivacaine for Pelvic Organ Prolapse
Status: RECRUITING
Conditions: Pelvic Organ Prolapse
Interventions: DRUG: Bupivacaine|OTHER: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Adding Ketamine to Low Dose Bupivacaine in Saddle Block for Perianal Surgery
Status: UNKNOWN
Conditions: Perianal Fistula|Hemorrhoids
Interventions: DRUG: Ketamine|DRUG: bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Quebec Pancreas Cancer Study
Status: RECRUITING
Conditions: Pancreas Cancer|Pancreatic Cancer|Pancreas Neoplasm|Pancreas Cyst|Pancreatic Precancerous Condition|Familial Pancreatic Cancer|Hereditary Cancer|Bile Duct Cancer|Ampullary Cancer|Duodenal Cancer|Gallbladder Cancer
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study With Ruxolitinib Phosphate Cream Applied Topically to Subjects With Alopecia Areata (AA)
Status: TERMINATED
Conditions: Alopecia Areata
Interventions: DRUG: Placebo Cream|DRUG: Ruxolitinib Phosphate Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Care of Cancer Patients With Bowel Injury Caused by Radiation Therapy to the Pelvis
Status: COMPLETED
Conditions: Cancer
Interventions: OTHER: educational intervention|OTHER: questionnaire administration|PROCEDURE: assessment of therapy complications|PROCEDURE: gastrointestinal complications management/prevention|PROCEDURE: management of therapy complications|PROCEDURE: quality-of-life assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Bioactive Materials in Pulp Therapy of Primary Teeth
Status: COMPLETED
Conditions: Pulpitis|Pulp Disease, Dental
Interventions: COMBINATION_PRODUCT: Bioceramic root repair material as pulp dressing in pulpotomy in primary molars|COMBINATION_PRODUCT: Mineral Trioxide Aggregate as pulp dressing in primary molars (MTA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Hypnobreastfeeding Education Given to Primiparas
Status: NOT_YET_RECRUITING
Conditions: Breastfeeding|Self Efficacy|Expectations
Interventions: BEHAVIORAL: Hypnobreastfeeding Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Empagliflozin Effect on Glucose Toxicity
Status: WITHDRAWN
Conditions: Type2 Diabetes Mellitus
Interventions: DRUG: Empagliflozin (Jardiance®)|DRUG: Insulin Glargine (Lantus®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Complete® Self-Expanding Stent and Stent Delivery System Registry
Status: COMPLETED
Conditions: Peripheral Vascular Disease
Interventions: DEVICE: Complete SE Iliac Stent|DEVICE: Complete SE Iliac Stent
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Postoperative Pain Control & Relief in Neonates
Status: TERMINATED
Conditions: Pain, Postoperative|Premature Infant|Opioid Use
Interventions: DRUG: Acetaminophen|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Glenohumeral Rotation After Throwing: RCT Comparing the Sleeper Stretch to the 90/90 Hip Lift With Balloon Blow Exercise
Status: COMPLETED
Conditions: Internal Rotation Contracture-shoulder
Interventions: OTHER: Sleeper Stretch|OTHER: 90/90 Hip Lift with Balloon Blow Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Nopal Fractions on Postprandial Glucose Regulation and Appetite Variables in Healthy Humans
Status: COMPLETED
Conditions: Glucose Tolerance|Appetite Sensations
Interventions: DIETARY_SUPPLEMENT: Nopal fractions|DIETARY_SUPPLEMENT: Test product without the active components
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Tailored Computerized Mobilization of the Cervical Spine Utilizing the Occiflex Device for the Treatment of Chronic Neck Pain
Status: COMPLETED
Conditions: Neck Pain
Interventions: DEVICE: Occiflex Robotic Intervention System
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects Of Berberine Plus Inulin On Diabetes Care in Patients With LADA
Status: NOT_YET_RECRUITING
Conditions: Type 1 Diabetes Mellitus|Autoimmune Diabetes
Interventions: DRUG: Berberine|DRUG: Inulin|DRUG: Berberine placebo tablets|DRUG: Inulin placebo tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: TOGETHER - Toronto: Trial to Evaluate the Effect of Peginterferon Lambda for the Treatment of COVID-19
Status: UNKNOWN
Conditions: Sars-CoV2|Covid19
Interventions: DRUG: Peginterferon Lambda-1A|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Determine the Short-Term Safety of Continuous Dosing of Abiraterone Acetate and Prednisone in Modified Fasting and Fed States to Patients With Metastatic Castration-Resistant Prostate Cancer
Status: COMPLETED
Conditions: Prostate Neoplasms|Prostate Cancer
Interventions: DRUG: Abiraterone|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating a Virtual Mentoring Program Plus Mental Health Videos for Teens
Status: RECRUITING
Conditions: Depressive Symptoms|Anxiety Disorders and Symptoms
Interventions: BEHAVIORAL: Appa Complete|BEHAVIORAL: Appa Lite
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A UK Interventional Trial in Premature Infants With Apnea of Prematurity Using a Simple, Non-invasive Vibratory Device to Study the Effectiveness in Supporting Breathing and General Stability
Status: UNKNOWN
Conditions: Apnea of Newborn|Hypoxia Neonatal|Bradycardia Neonatal
Interventions: DEVICE: WAVE device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Henagliflozin's Impact on Prediabetes Remission
Status: NOT_YET_RECRUITING
Conditions: PreDiabetes|Prediabetic State|Type 2 Diabetes|Glucose Metabolism Disorders
Interventions: DRUG: Henagliflozin 5mg|DRUG: Henagliflozin 10mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Subcutaneous Immunotherapy in Birch Pollen Allergic Patients
Status: TERMINATED
Conditions: Allergy
Interventions: BIOLOGICAL: Subcutaneous immunotherapy - Recombinant birch pollen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: The Impact of Botox® During Robotic Rehabilitation of the Wrist Following Stroke
Status: COMPLETED
Conditions: Stroke
Interventions: OTHER: Botox®|OTHER: saline solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Functional Effect of Treatment of Glottic Insufficiency With Calcium Hydroxyapatite
Status: COMPLETED
Conditions: Glottic Insufficiency
Interventions: PROCEDURE: Calcium Hydroxyapatite|DEVICE: Radiesse Voice (Calcium Hydroxyapatite)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sodium Bicarbonate for the Treatment of Severe Metabolic Acidosis With Moderate or Severe Acute Kidney Injury in ICU
Status: COMPLETED
Conditions: Metabolic Acidosis|Acute Kidney Injury
Interventions: DRUG: Sodium bicarbonate infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Randomized, Double-blind, Two Arms, Multicenter, Phase III Study of Berinert for Treatment of ACE Induced Angioedema
Status: COMPLETED
Conditions: Acute ACE-induced Angioedema
Interventions: DRUG: Berinert|DRUG: Clemastin|DRUG: Cortisone acetate|DRUG: NaCl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment Outcomes of a Novel Glaucoma Tube Shunt Implant for Intraocular Pressure Control in Eyes With Refractory Glaucoma
Status: COMPLETED
Conditions: Glaucoma|Glaucoma, Open-Angle|Surgery|Intraocular Pressure
Interventions: DEVICE: Paul Glaucoma Implant Surgery
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Natural Killer(NK) Cell Therapy for AML Minimal Residual Disease
Status: RECRUITING
Conditions: Minimal Residual Disease
Interventions: DRUG: QN-030a|DRUG: Cyclophosphamid|DRUG: Fludarabine|DRUG: Cytarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cannabidiol and Oral Contraceptive Pills: Exploring a Drug-Drug Interaction
Status: COMPLETED
Conditions: Contraception
Interventions: DRUG: Cannabidiol Oil|DRUG: Placebo|DRUG: Combined oral contraceptive pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Multi-speed Ergonomic Wheelchair
Status: RECRUITING
Conditions: Spinal Cord Diseases|Spinal Cord Injuries
Interventions: DEVICE: Single Speed Ergonomic Wheelchair|DEVICE: Multi-Speed Ergonomic Wheelchair
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Diagnostic Validity of [18F]GP1 PET for Diagnosing Acute Deep Vein Thrombosis
Status: RECRUITING
Conditions: Venous Thrombosis
Interventions: DRUG: [18F]GP1 positron emission tomography/computed tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy and Safety of Oral Semaglutide Versus Placebo in Subjects With Type 2 Diabetes Mellitus Treated With Diet and Exercise Only
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: semaglutide|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Desflurane-propofol Balanced Anesthesia on Visual Evoked Potentials Monitoring
Status: RECRUITING
Conditions: Visual Evoked Potentials
Interventions: DRUG: Desflurane|DRUG: Desflurane, Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effectiveness of Battlefield Acupuncture (BFA) With Standard Therapy in Gynecological Cancer Pain
Status: COMPLETED
Conditions: Gynecologycal Cancer|Cancer Related Pain|Cancer Pain
Interventions: DEVICE: Press Needle Acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluate Risk/Benefit of Nab Paclitaxel in Combination With Gemcitabine and Carboplatin Compared to Gemcitabine and Carboplatin in Triple Negative Metastatic Breast Cancer (or Metastatic Triple Negative Breast Cancer)
Status: COMPLETED
Conditions: Breast Tumor|Breast Cancer|Cancer of the Breast|Estrogen Receptor- Negative Breast Cancer|HER2- Negative Breast Cancer|Progesterone Receptor- Negative Breast Cancer|Recurrent Breast Cancer|Stage IV Breast Cancer|Triple-negative Breast Cancer|Triple-negative Metastatic Breast Cancer|Metastatic Breast Cancer
Interventions: DRUG: nab-Paclitaxel|DRUG: Carboplatin|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hetrombopag for the Thrombocytopenia Induced by Concurrent Chemoradiotherapy
Status: RECRUITING
Conditions: Thrombocytopenia|Radiotherapy Side Effect
Interventions: DRUG: Hetrombopag Olamine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Adebrelimab Combined With Dalpiciclib and Standard Endocrine Therapy for HR+/HER2 - Advanced Breast Cancer
Status: RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Adebrelimab|DRUG: dalpiciclib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Osteoplasty in Conjunction With Surgical Treatment of Mandibular Grade II Furcation Defects
Status: WITHDRAWN
Conditions: Furcation Defects|Periodontal Diseases
Interventions: PROCEDURE: Open flap debridement with osteoplasty|PROCEDURE: Open flap debridement without osteoplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Muscle Energy Technique on Craniovertebral and Shoulder Angles in Forward Head Posture
Status: ACTIVE_NOT_RECRUITING
Conditions: Forward Head Posture
Interventions: OTHER: exersice program (Muscle energy technique)|OTHER: exersice program (stretching and strengthening exercises ) In addition to postural advices
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Best Endovascular vs. Best Surgical Therapy in Patients With Critical Limb Ischemia
Status: COMPLETED
Conditions: Critical Limb Ischemia
Interventions: PROCEDURE: Open surgical revascularization|DEVICE: Endovascular revascularization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of LY2624803 in Participants With Transient Insomnia
Status: COMPLETED
Conditions: Transient Insomnia
Interventions: DRUG: LY2624803 - Capsules|DRUG: Zolpidem - Tablets|DRUG: Placebo - Capsules|DRUG: Placebo - Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: A 12 -Month, Open-label, Multi-center Study to Explore the Health Outcomes of FTY720
Status: COMPLETED
Conditions: Multiple Sclerosis|Relapsing-Remitting
Interventions: DRUG: Fingolimod
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of Clinical Equivalence Between Two Lubiprostone Products in the Treatment of Chronic Idiopathic Constipation
Status: COMPLETED
Conditions: Chronic Idiopathic Constipation
Interventions: DRUG: Lubiprostone|DRUG: Lubiprostone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT