pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Calciying Tendinopathy of the Rotator Cuff: Barbotage Vs Shock Waves
Status: RECRUITING
Conditions: Tendinopathy Rotator Cuff|Calcific Tendinitis|High-Energy Shock Waves|Barbotage|Pain, Shoulder
Interventions: PROCEDURE: shockwave therapy|PROCEDURE: Barbotage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic, Efficacy, and Safety Study of Octafibrin Compared to Haemocomplettan/Riastap
Status: COMPLETED
Conditions: Congenital Fibrinogen Deficiency|Afibrinogenemia
Interventions: BIOLOGICAL: Octafibrin|BIOLOGICAL: Haemocomplettan® P or RiaSTAPTM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Crohn's Disease Exclusion Diet on Top of Standard Therapy Versus Standard Therapy Alone in Unstable Pediatric Crohn's Disease Patients.
Status: RECRUITING
Conditions: Crohn's Disease
Interventions: DIETARY_SUPPLEMENT: Phase1 : CDED/Modulen™IBD® + Maintenance therapy|DIETARY_SUPPLEMENT: Phase2 and 3 :
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Probiotic Supplementation in the Immune Response of Participants With COVID-19 (Coronavirus Disease).
Status: COMPLETED
Conditions: Covid19
Interventions: DIETARY_SUPPLEMENT: Probiotic: Lactobacillus salivarius + Vit D + Zinc|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Time-restricted Feeding in NAFLD
Status: RECRUITING
Conditions: Fatty Liver Disease|Fatty Liver|Fatty Liver, Nonalcoholic
Interventions: BEHAVIORAL: Intermittent fasting|BEHAVIORAL: DGE diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: TissueLink Versus SEAMGUARD After Distal Pancreatectomy
Status: TERMINATED
Conditions: Distal Pancreatectomy
Interventions: DEVICE: SEAMGUARD with bioabsorbable staple|PROCEDURE: TissueLink with radiofrequency ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Omitting GnRH-antagonist Dose on the Day of Ovulation Trigger
Status: UNKNOWN
Conditions: Pituitary Downregulation
Interventions: DRUG: Omit Citrotide 0.25 dose on the day of triggering of ovulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Performance, Safety and Efficiency Comparison Between 10,000 and 5,000 Cuts Per Minute Vitrectomy Using a 25G Cutter - A Prospective Randomized Controlled Study
Status: COMPLETED
Conditions: Vitreous Hemorrhage|Macula Hole|Epiretinal Membrane|Retinal Detachment
Interventions: DEVICE: Alcon 25Gauge, 10,000 cuts per minute Ultravit cutter|DEVICE: Alcon 25Gauge, 5,000 cuts per minute Ultravit cutter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of PG-530742 in the Treatment of Mild to Moderate Knee Osteoarthritis
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: DRUG: PG-530742|DRUG: Placebo|DRUG: 50 mg PG-530742|DRUG: 100 mg PG-530742|DRUG: 200 mg PG-530742
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Local Manufacture of CAR T-Cell Products for the Treatment of B-Cell Lymphoma and B-Acute Lymphoblastic Leukemia
Status: RECRUITING
Conditions: B-Cell Lymphoma|B Acute Lymphoblastic Leukemia|Diffuse Large B Cell Lymphoma|Mantle Cell Lymphoma|Follicular Lymphoma|Marginal Zone Lymphoma|Lymphoplasmacytic Lymphoma|Chronic Lymphocytic Leukemia|Transformed Lymphoma
Interventions: DRUG: Chimeric Antigen Receptor (CAR) T-Cell Product (Autologous)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Coformulated Favezelimab/Pembrolizumab (MK-4280A) Versus Standard of Care in Subjects With Previously Treated Metastatic PD-L1 Positive Colorectal Cancer (MK-4280A-007)-China Extension Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Colorectal Cancer
Interventions: BIOLOGICAL: favezelimab/pembrolizumab|DRUG: regorafenib|DRUG: TAS-102
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cornerstone Program for Transition-Age Youth Study Protocol for a Randomized Controlled Trial
Status: COMPLETED
Conditions: Depression|Stress Disorders, Post-traumatic|Bipolar Disorder
Interventions: BEHAVIORAL: Treatment As Usual|BEHAVIORAL: Cornerstone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Influence of Different Thyroid Autoantibodies on Thyroid Function and Pregnancy Outcome After Assisted Reproductive Technology
Status: UNKNOWN
Conditions: Fertility Disorders|Thyroid Dysfunction
Interventions: DIAGNOSTIC_TEST: blood test|OTHER: follow up treatment outcome
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Phase II Study of Regorafenib and Toripalimab Combined With RFA in Patients With CRCLM
Status: UNKNOWN
Conditions: Colorectal Cancer Liver Metastases
Interventions: OTHER: Radiofrequency ablation|DRUG: Regorafenib and Toripalimab Combination
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Management of Cervical Intraepithelial Neoplasia Grade 2
Status: COMPLETED
Conditions: Cervical Intraepithelial Neoplasia
Interventions: PROCEDURE: Excision of the lesion|OTHER: Follow-up for spontaneous regression of the lesion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Cognitive Rehabilitation and Brain Activity of Attention Control in TBI
Status: WITHDRAWN
Conditions: Brain Injuries, Traumatic
Interventions: BEHAVIORAL: Direct-attention training using web-based BrainHQ|BEHAVIORAL: Goal Management Training (GMT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: High Frequency Oscillatory Ventilation Combined With Intermittent Sigh Breaths: Effects on Blood Oxygenation and Stability of Oxygenation
Status: UNKNOWN
Conditions: Respiratory Distress Syndrome, Newborn|Bronchopulmonary Dysplasia|Ventilator Induced Lung Injury
Interventions: OTHER: HFOV combined with sigh breaths
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intraoperative Folate Targeted Fluorescence in Renal Cell Carcinoma
Status: COMPLETED
Conditions: Renal Cell Carcinoma
Interventions: DRUG: OTL38|DEVICE: Intraoperative fluorescence imaging system
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of a Post-operative Protocol of Early Mobilization on Functional Recovery and Postoperative Complications After Immediate Internal Pudendal Artery Perforator Flap Reconstruction for Irradiated Abdominoperineal Resection Defects: a Prospective, Randomized and Controlled Clinical Study.
Status: UNKNOWN
Conditions: Rectal Cancer
Interventions: OTHER: Early mobilization strategy adapted after immediate internal pudendal artery perforator flap reconstruction for abdominoperineal resection (intervention group).
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Plant-Based Whole-Foods Meal Delivery Service for Patients With Multiple Myeloma Undergoing Autologous Hematopoietic Cell Transplant
Status: NOT_YET_RECRUITING
Conditions: Multiple Myeloma
Interventions: PROCEDURE: Biospecimen Collection|OTHER: Dietary Intervention|OTHER: Dietary Intervention|OTHER: Medical Chart Review|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Elotuzumab, CC-92480, and Dexamethasone for the Treatment of Relapsed or Refractory Myeloma After CD38- and BCMA-Targeted Therapies
Status: RECRUITING
Conditions: Recurrent Multiple Myeloma|Refractory Multiple Myeloma
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Bone Marrow Aspiration|PROCEDURE: Bone Marrow Biopsy|PROCEDURE: Computed Tomography|DRUG: Dexamethasone|PROCEDURE: Echocardiography|BIOLOGICAL: Elotuzumab|PROCEDURE: Magnetic Resonance Imaging|BIOLOGICAL: Mezigdomide|PROCEDURE: X-Ray Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treating Psychotic Symptoms of Young Individuals Presenting a First Episode of Schizophrenia: Comparison of Two State-of-the-Art Interventions
Status: COMPLETED
Conditions: Schizophrenia
Interventions: BEHAVIORAL: Cognitive-Behavioral therapy and Symptom Management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Study Of Letrozole With Or Without Palbociclib (PD-0332991) For The First-Line Treatment Of Hormone-Receptor Positive Advanced Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: PD 0332991|DRUG: letrozole|DRUG: letrozole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Thrombolysis Versus Primary Angioplasty for AMI in Elderly Patients
Status: TERMINATED
Conditions: Acute Myocardial Infarction
Interventions: DRUG: Tenecteplase + UFH (+ clopidogrel, since 01/97)|PROCEDURE: Primary angioplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lapatinib Ditosylate, Trastuzumab, Paclitaxel, and Surgery in Treating Patients With Breast Cancer
Status: COMPLETED
Conditions: HER2-positive Breast Cancer|Stage II Breast Cancer|Stage IIIA Breast Cancer
Interventions: DRUG: lapatinib ditosylate|DRUG: paclitaxel|BIOLOGICAL: trastuzumab|PROCEDURE: therapeutic conventional surgery|OTHER: pharmacological study|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Impact of Second-look Endoscopy After Endoscopic Submucosal Dissection of Gastric Neoplasm
Status: UNKNOWN
Conditions: Gastric Neoplasms
Interventions: PROCEDURE: second look endoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Mobilization With Post- Isometric Relaxation in Neck Pain Associated With Myofascial Trigger Points
Status: COMPLETED
Conditions: Mechanical Neck Pain
Interventions: OTHER: Post Isometric relaxation Technique (PIR)|OTHER: Cervical Mobilization (CM)|OTHER: conventional treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CAR-Multicenter Analysis (CAR-MA): Retrospective Study to Characterize CAR T-cell Outcomes and Related Toxicities in Children and Young Adults With B-ALL
Status: ACTIVE_NOT_RECRUITING
Conditions: Leukemia, Acute Lymphoblastic|Lymphoblastic Leukemia, Acute, Childhood
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pembrolizumab and Disitamab Vedotin in HER2-expressing Metastatic Colorectal Cancer
Status: NOT_YET_RECRUITING
Conditions: Colorectal Neoplasms
Interventions: DRUG: Pembrolizumab|DRUG: Disitamab vedotin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Preliminary Effectiveness of BNT327, an Investigational Therapy for Patients With Small-cell Lung Cancer in Combination With Chemotherapy
Status: RECRUITING
Conditions: Extensive-stage Small-cell Lung Cancer|Small-cell Lung Cancer
Interventions: DRUG: BNT327 Dose Level 1 (DL1)|DRUG: BNT327 Dose Level 2 (DL2)|DRUG: Topoisomerase Inhibitor A|DRUG: Alkylating agent|DRUG: Taxane|DRUG: Topoisomerase Inhibitor B
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Centralised Anesthesic Monitoring in the Surgery of the Ocular Anterior Segment: Non Inferiority Study
Status: COMPLETED
Conditions: Ambulatory Surgical Procedures|Ocular Anterior Segment Surgery
Interventions: OTHER: Health care organization (anesthetic surveillance)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Venous Sinus Stenting for Idiopathic Intracranial Hypertension Refractory to Medical Therapy
Status: COMPLETED
Conditions: Idiopathic Intracranial Hypertension (IIH)
Interventions: DEVICE: Venous Sinus Stenting
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Relaxation Therapy for Pain, Fatigue and Vital Signs in Post-operation With Head and Neck Cancer
Status: COMPLETED
Conditions: Progressive Muscle Relaxation on Postoperative Pain, Fatigue, and Vital Signs in Patients With Head and Neck Cancers
Interventions: BEHAVIORAL: progressive muscle relaxation|BEHAVIORAL: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Phase II Study of Neoadjuvant Immunotherapy in Combination With Chemotherapy in Locally Advanced Head and Neck Squamous Cell Carcinoma
Status: NOT_YET_RECRUITING
Conditions: Head and Neck Squamous Cell Carcinoma
Interventions: DRUG: Ivonescimab combined with TP|DRUG: Cadonilimab combined with TP|DRUG: Penpulimab combined with TP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testing the Feasibility and Acceptability of Social Media and Digital Therapeutics to Decrease Vaping Behaviors
Status: NOT_YET_RECRUITING
Conditions: Nicotine Vaping|Nicotine Use Disorder
Interventions: DEVICE: quitSTART Mobile Application|BEHAVIORAL: Chatbot Feature in quitSTART Mobile Application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Avastin (Bevacizumab) Combined With Chemotherapy in Patients With Metastatic Cancer of the Colon or Rectum
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: bevacizumab [Avastin]
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Pharmacokinetics of Oral BIBP 5371 CL in Healthy Male and Female Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BIBP 5371 CL tablet|DRUG: BIBP 5371 CL solution|OTHER: High fat, high caloric breakfast|DRUG: Placebo tablet|DRUG: BIBP 5371 CL tablet high dose|DRUG: Placebo drinking solution|DRUG: BIBP 5371 CL tablet low dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Intra-anal Nifedipine, Used As Add-on to Conservative Therapy, on Pain in Patients With Anal Fissure
Status: COMPLETED
Conditions: Chronic Anal Fissure
Interventions: DRUG: Nifedipine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Effects of Propioceptive Neuromascular Facilitation and Neural Flossing in Diabetic Neuropathy
Status: RECRUITING
Conditions: Diabetic Peripheral Neuropathy
Interventions: OTHER: Propioceptive Neuromascular facilitation|OTHER: Neural Flossing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 1b Multiple Ascending Dose Study of Foralumab in Primary and Secondary Progressive MS
Status: WITHDRAWN
Conditions: Primary Progressive Multiple Sclerosis|Secondary Progressive Multiple Sclerosis|Multiple Sclerosis
Interventions: DRUG: Intranasal Foralumab Solution|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Discontinuation of Hypnotics in Older Veterans
Status: COMPLETED
Conditions: Insomnia
Interventions: BEHAVIORAL: CBTI plus taper method A|BEHAVIORAL: CBTI plus taper method B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: DiaFrail: A Short Duration Study in Older People ( DIAFRAIL Study)
Status: WITHDRAWN
Conditions: Diabetes Mellitus
Interventions: DRUG: Metformin|DRUG: Glimepiride|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Efficacy of CareAide® App in Improving Adherence in Adults With Chronic Diseases
Status: RECRUITING
Conditions: Adherence, Medication|Chronic Disease|Quality of Life|Economic Burden|Asthma|Hypertension|Heart Failure|Diabetes
Interventions: OTHER: CareAide App Usage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Current Exercise Approaches in Patients With Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: OTHER: Cawthorne-Cooksey Exercises|OTHER: Mechanical Hippotherapy Exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Weight-bearing Radiographs to Evaluate Stability in Ankles With Isolated Weber Type B Fractures.
Status: COMPLETED
Conditions: Lateral Malleolus Fractures|Ankle Fractures
Interventions: PROCEDURE: Open reduction internal fixation (ORIF)|OTHER: Conservative treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Open-Label C1 Esterase Inhibitor (C1INH-nf) for the Prevention of Acute Hereditary Angioedema (HAE) Attacks
Status: COMPLETED
Conditions: Hereditary Angioedema
Interventions: BIOLOGICAL: C1 esterase inhibitor [human] (C1INH-nf)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Biliary Metal Stent Study: Metal Stents for Management of Distal Malignant Biliary Obstruction
Status: COMPLETED
Conditions: Bile Duct Obstruction|Pancreatic Cancer|Gallbladder Cancer|Bile Duct Cancer
Interventions: DEVICE: "Nitinella" ; SX-ELLA Stent Biliary (biliary metal stent)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Collaborative Network to Take Responsibility for Oral Anticancer Therapy
Status: UNKNOWN
Conditions: Breast Cancer|ALL|Lung Cancer|Melanoma|Colorectal Cancer|Prostate Cancer
Interventions: OTHER: Implementation of a care pathway
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Optimal Blood Pressure for the prevenTIon of Major vAscuLar Events in Stroke Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Ischemic Stroke|Blood Pressure|Cognitive Impairment|Vascular Diseases
Interventions: DRUG: Intensive Control of Systolic Blood Pressure (SBP)|DRUG: Standard control of Systolic Blood Pressure (SBP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Pharmacokinetics of Halix(TM) Albuterol Unit Dose Disposable Inhaler Versus Albuterol MDI
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Albuterol DPI 90mcg|DRUG: Albuterol DPI 180mcg|DRUG: Albuterol HFA MDI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Time-restricted Eating and Exercise Training on Skeletal Muscle Mass Quantity, Quality and Function in Postmenopausal Women With Overweight and Obesity
Status: RECRUITING
Conditions: Menopause Related Conditions|Sarcopenia|Osteoporosis Postmenopausal|Obesity
Interventions: BEHAVIORAL: Time Restricted Eating (TRE)|BEHAVIORAL: Exercise|BEHAVIORAL: Caloric Restriction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Epinephrine Inhalation Aerosol USP, CLINICAL STUDY-B3 FOR ASSESSMENT OF PHARMACOKINETICS
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Arm T1: Primatene Mist HFA|DRUG: Arm T2: Primatene Mist HFA|DRUG: Arm C: Primatene Mist (epinephrine inhalation aerosol, USP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Determine the Fed Bioequivalence of Reformulated OXY Tablets and Original OxyContin® (OXY) Tablets
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Reformulated OXY (oxycodone HCl)|DRUG: Original OxyContin® (OXY) (oxycodone HCl)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Ultrasound Guided Psoas Compartment Block vs Suprainguinal Fascia Iliaca Compartment Block
Status: UNKNOWN
Conditions: Pain, Postoperative|Hip Dysplasia
Interventions: DRUG: Fentanyl|DRUG: Propofol|DRUG: Rocuronium|DRUG: Sevoflurane|DRUG: Ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: OTHER
Clinical trial: Pazopanib Hydrochloride With or Without Ascorbic Acid in Treating Patients With Kidney Cancer That Is Metastatic or Cannot Be Removed by Surgery
Status: TERMINATED
Conditions: Clear Cell Renal Cell Carcinoma|Metastatic Clear Cell Renal Cell Carcinoma|Stage III Renal Cell Cancer AJCC v8|Stage IV Renal Cell Cancer AJCC v7|Unresectable Renal Cell Carcinoma
Interventions: DRUG: Ascorbic Acid|DRUG: Pazopanib Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Techniques to Reduce the Severity and Frequency of Emergent Reactions
Status: TERMINATED
Conditions: Analgesia
Interventions: BEHAVIORAL: Do we speak to them in a way that convinces them to have the dream|BEHAVIORAL: Speaking to them as a regualar person
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Bio Impedance Monitoring as a Tool to Assess Fluid Status in the Pediatric Surgical Patient? (PedFluid Study)
Status: RECRUITING
Conditions: Fluid and Electrolyte Imbalance|Body Weight Changes|Children, Only
Interventions: DIAGNOSTIC_TEST: bio impedance spectroscopy by means of the Body Composition Monitor (Name of the device is BCM from Fresenius Medical Care D GmbH)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Bioequivalence Study of Perindopril /Amlodipine/Indapamide 8 mg (10 mg)/2.5 mg/10 mg Tablets in Healthy Volunteers Under Fasting Conditions
Status: RECRUITING
Conditions: Bioequivalence
Interventions: DRUG: Perindopril/Indapamide/Amlodipine 8 mg/2.5 mg/10 mg tablet / Triplixam® 10 mg/2.5 mg/10 mg tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: The AI-CAC Model for Subclinical Atherosclerosis Detection on Chest X-ray
Status: NOT_YET_RECRUITING
Conditions: Cardiovascular Diseases|Atherosclerosis|Coronary Artery Calcification
Interventions: DIAGNOSTIC_TEST: AI-CAC score
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Phase II Trial of Neoadjuvant Treatment and Minimal Invasive Surgery for Esophageal and GEJ Cancer
Status: UNKNOWN
Conditions: Esophageal Cancer|Induction Chemotherapy
Interventions: DRUG: carboplatin paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: IDO Inhibitor Study for Relapsed or Refractory Solid Tumors
Status: TERMINATED
Conditions: Breast Cancer|Lung Cancer|Melanoma|Pancreatic Cancer|Solid Tumors
Interventions: DRUG: 1-methyl-D-tryptophan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of ABT-263 in Subjects With Relapsed or Refractory Lymphoid Malignancies
Status: COMPLETED
Conditions: Chronic Lymphoid Leukemia|Lymphoid Malignancies|Non-Hodgkin's Lymphoma|Follicular Lymphoma|Mantle Cell Lymphoma|Peripheral T-cell Lymphoma
Interventions: DRUG: ABT-263
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Can Hypermobility of First Ray Affect Surgical Treatment of Hallux Valgus
Status: UNKNOWN
Conditions: Hallux Valgus
Interventions: PROCEDURE: Corrective osteotomy|PROCEDURE: Fusion of First ray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Manhattan Vision Screening and Follow-Up Study (NYC-SIGHT)
Status: ACTIVE_NOT_RECRUITING
Conditions: Glaucoma|Vision Impairment and Blindness|Cataract|Diabetic Retinopathy|Eye Diseases
Interventions: BEHAVIORAL: Enhanced Intervention Using Patient Navigators|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: A Clinical Study on Evaluating Intravenous Administration of IDOV-SAFE
Status: RECRUITING
Conditions: Advanced Malignant Solid Tumor of Digestive System
Interventions: BIOLOGICAL: IDOV-SAFE
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Sildenafil and Outcome of IVF/ICSI Cycles
Status: UNKNOWN
Conditions: Infertility, Female
Interventions: DRUG: Sildenafil vaginal suppositories|OTHER: vaginal placebo|OTHER: vaginal placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: BEATRIS Study: A Study of Adherence to Bonviva (Ibandronate) Once Monthly in Women With Post-Menopausal Osteoporosis
Status: COMPLETED
Conditions: Postmenopausal Osteoporosis
Interventions: DRUG: ibandronate [Bonviva/Boniva]|DRUG: ibandronate [Bonviva/Boniva]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose Response Effects of Marine Omega-3 Fatty Acids on Inflammation
Status: COMPLETED
Conditions: Cardiovascular Disease|Inflammation
Interventions: BIOLOGICAL: Eicosapentaenoic Acid and Docosahexaenoic Acid (EPA + DHA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Single-center Pilot Study Evaluating a Preemptive Short Course of Glecaprevir/Pibrentasvir in Hepatitis C Positive to Negative Kidney Transplantation
Status: COMPLETED
Conditions: ESRD
Interventions: DRUG: Glecaprevir/pibrentasvir
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Can Valacyclovir Attenuate Inflammation in Antiretroviral-Treated HIV-Infected Individuals With Herpes Simplex Virus Type 2?
Status: COMPLETED
Conditions: Human Immunodeficiency Virus|Herpes Simplex
Interventions: DRUG: Valacyclovir|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Behavioral or Solifenacin Therapy for Urinary Symptoms in Parkinson Disease
Status: COMPLETED
Conditions: Overactive Bladder|Parkinson Disease
Interventions: DRUG: solifenacin|BEHAVIORAL: Pelvic floor muscle exercise-based behavioral therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Insulin Sensitivity of the Brain in Pathogenesis of Diabetes Mellitus Type 2
Status: UNKNOWN
Conditions: Human Physiology of Energy Homeostasis
Interventions: DRUG: Human insulin|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Sotorasib in Advanced KRASG12C-mutated Non-small Cell Lung Cancer Patients With Comorbidities
Status: RECRUITING
Conditions: Lung Cancer|NSCLC, Stage III|NSCLC Stage IV|Lung Cancer Stage IV|Mutation|Cancer|Cancer, Lung
Interventions: DRUG: sotorasib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Changes in Echogenicity and Muscle Stiffness in Elastography After Botulinum Toxin Injection a Spastic Muscle
Status: TERMINATED
Conditions: Stroke
Interventions: DEVICE: ultrasound echogenicity|DEVICE: elastography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Using CHWs or Mailing Self Sampling Home Tests to Increase Cervical Cancer Screening in South Florida
Status: COMPLETED
Conditions: Cervical Cancer
Interventions: BEHAVIORAL: CHW and Self-sampling for Cervical Cancer|BEHAVIORAL: Mailed Self Sampler
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Use of Adipose Derived Regenerative Cells in Bilateral Femoral Head Osteonecrosis
Status: TERMINATED
Conditions: Osteonecrosis
Interventions: OTHER: Lactated Ringers|DEVICE: The Celution 800/GP System (Cytori Therapeutics)|BIOLOGICAL: Adipose Derived Regenerative Cells (ADRC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Positive Outcomes of the Supplementation With Lecithin-based Delivery Form of Curcuma Longa and of Boswellia Serrata in IBS
Status: COMPLETED
Conditions: Boswellia Serrata|Irritable Bowel Syndrome
Interventions: DIETARY_SUPPLEMENT: Curcuma and boswellia extracts plus low fodmap diet|OTHER: Low Foodmap diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Photobiomodulation Therapy Combined With Static Magnetic Field on the Subsequent Performance
Status: COMPLETED
Conditions: Skeletal Muscle Performance
Interventions: DEVICE: Active PBMT-sMF|DEVICE: Placebo PBMT-sMF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Bioavailability of Carotenoids Present in Mamey Sapote (Pouteria Sapota (Jacq.) H. E. Moore & Stearn) Fruit
Status: COMPLETED
Conditions: Biological Availability
Interventions: OTHER: Fruit Smoothie|OTHER: Matrix-Free Shake
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Acupuncture With/Without Self-acupressure for Post-oophorectomy Hot Flashes in BRCA Carriers
Status: NOT_YET_RECRUITING
Conditions: Hot Flashes|Menopause Surgical
Interventions: OTHER: Acupuncture|OTHER: Acupuncture-Acupressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Comparing Etanercept in Combination With Methotrexate in Subjects With Rheumatoid Arthritis
Status: COMPLETED
Conditions: Arthritis, Rheumatoid
Interventions: DRUG: Etanercept|DRUG: Methotrexate|DRUG: Etanercept|DRUG: Methotrexate|DRUG: Placebo|DRUG: Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: NBTXR3 Activated by Radiation Therapy for the Treatment of Locally Advanced or Borderline-Resectable Pancreatic Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Borderline Resectable Pancreatic Adenocarcinoma|Locally Advanced Pancreatic Ductal Adenocarcinoma|Resectable Pancreatic Ductal Adenocarcinoma|Stage III Pancreatic Cancer AJCC v8
Interventions: OTHER: Hafnium Oxide-containing Nanoparticles NBTXR3|RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I Trial of Intraperitoneal Bevacizumab in Refractory Malignant Ascites
Status: UNKNOWN
Conditions: Refractory Malignant Ascites
Interventions: DRUG: bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of NDV-3A Vaccine in Preventing S. Aureus Colonization
Status: COMPLETED
Conditions: Staphylococcus Aureus
Interventions: BIOLOGICAL: NDV-3A|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Autologous Cell-derived Tissue Engineered Cartilage for Repairing Articular Cartilage Lesions
Status: UNKNOWN
Conditions: Cartilage Diseases
Interventions: BIOLOGICAL: biomimetic cartilage matrix + autologous chondrocytes|PROCEDURE: arthroscopic debridement|PROCEDURE: microfracture surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Regenn® Therapy System Safety Study
Status: NOT_YET_RECRUITING
Conditions: Surgical Wound
Interventions: DEVICE: Regenn® Negative Pressure Therapy System|DEVICE: Prevena™ Incision Management System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pathological Validation of Functional Imaging in Head and Neck Squamous Cell Carcinoma
Status: TERMINATED
Conditions: Head and Neck Cancer
Interventions: OTHER: A polymerase chain reaction -based hypoxia classifier|OTHER: Functional imaging before treatment.|OTHER: Immunohistochemical staining|OTHER: MRI of the resection specimen|OTHER: Tumour volume delineation and comparison
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study Evaluating Implementation Strategies for the Delivery of APRETUDE for Black cis-and Transgender Women in United States EHE Territories
Status: RECRUITING
Conditions: HIV Infections
Interventions: DRUG: APRETUDE|DRUG: Cabotegravir tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Accelerated rTMS for the Reduction of Nicotine Craving
Status: TERMINATED
Conditions: Nicotine Use Disorder|Nicotine Dependence
Interventions: DEVICE: Active rTMS with MagVenture MagPro double blind rTMS system|DEVICE: Sham rTMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Platelet Concentrates on Palatal Wound Healing
Status: COMPLETED
Conditions: Wound Heal|Platelets; Defect|Periodontal Inflammation|Gingival Recession
Interventions: BIOLOGICAL: AFG application on palatinal wound healing|BIOLOGICAL: i-PRF application on palatinal wound healing|OTHER: control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Preventing Addiction Related Suicide (PARS)
Status: COMPLETED
Conditions: Suicide|Substance-Related Disorders
Interventions: BEHAVIORAL: Preventing Addiction Related Suicide (PARS)|BEHAVIORAL: Intensive Outpatient Program standard session
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of a Combined Use of Mosquito Repellent and Insecticide Treated Net on Malaria in Ethiopia
Status: COMPLETED
Conditions: Malaria|Mosquito Repellent|Long Lasting Insecticidal Nets
Interventions: OTHER: Mosquito repellent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Multicenter Randomized Placebo-Controlled Double-Blind Study to Assess Efficacy and Safety of Glutamine and Creatine Monohydrate in Duchenne Muscular Dystrophy (DMD)
Status: COMPLETED
Conditions: Muscular Dystrophy, Duchenne
Interventions: DRUG: glutamine|DRUG: creatine monohydrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Impact of Maternal Body Weight on Vitamin D Status During Pregnancy
Status: COMPLETED
Conditions: Obesity|Vitamin D Deficiency
Interventions: DIETARY_SUPPLEMENT: Pregnancy multi-vitamin (including 10μg vitamin D3)|DIETARY_SUPPLEMENT: 10μg vitamin D3|DIETARY_SUPPLEMENT: 0μg vitamin D (placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Intrathecal Ketamine, Dexmedetomidine and Both With Bupivacaine for Postoperative Abdominal Cancer Surgery Pain
Status: UNKNOWN
Conditions: Therapy|Pain Management
Interventions: PROCEDURE: intrathecal drug administration|DRUG: Dexmedetomidine|DRUG: ketamine|DRUG: Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Locating Nociceptive Stimuli on Digital Body Chart
Status: COMPLETED
Conditions: Low Back Pain|Healthy Volunteers
Interventions: OTHER: Electrocutaneous stimulation|OTHER: Assessment + Electrocutaneous stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect of Stress Reduction Program on Pregnancy Process and Mental Health in High Risk Pregnant Women
Status: COMPLETED
Conditions: Pregnancy, High Risk|Depression, Postpartum|Anxiety in Pregnancy|Stress Disorder
Interventions: BEHAVIORAL: cognitive behavioral approach-based stress reduction program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: OTHER
Clinical trial: Compare Two Dosing Algorithms in Insulin-Naive Patients With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: simplified diabetes regimen starting with a fixed dose of Human Insulin Inhalation Powder|DRUG: intensive diabetes management starting with an adjusted dose of Human Insulin Inhalation Powder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Study of Reconstituted JUVÉDERM® Ultra vs COSMODERM® 1 for Lip and Cheek Lines, Folds or Wrinkles
Status: COMPLETED
Conditions: Intrinsic Aging of Skin
Interventions: DEVICE: Juvéderm Ultra|DEVICE: Cosmoderm 1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Policosanol as Monotherapy and Adjunctive to Statin Therapy
Status: COMPLETED
Conditions: High Cholesterol
Interventions: DRUG: Policosanol|OTHER: Placebo|DRUG: Policosanol Plus Already In Use Statin Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Preventing Opioid Overdose Deaths by Empowering Pharmacists to Dispense Naloxone
Status: COMPLETED
Conditions: Opioid Overdose
Interventions: BEHAVIORAL: Educational Webinar|BEHAVIORAL: Resources|BEHAVIORAL: Reminders
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Intraoperative Cell Salvage and Hemodilution Technique in Scoliosis Surgery
Status: COMPLETED
Conditions: Adolescent Idiopathic Scoliosis
Interventions: PROCEDURE: cell salvage technique|PROCEDURE: acute normovolemic hemodilution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of Avastin (Bevacizumab) in Combination With Chemotherapy in Patients With Previously Untreated Metastatic Colorectal Cancer.
Status: WITHDRAWN
Conditions: Colorectal Cancer
Interventions: DRUG: bevacizumab [Avastin]|DRUG: Irinotecan|DRUG: Leucovorin|DRUG: 5 FU|DRUG: Cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SEPREVEN: a Stepped-wedge Randomised Controlled Trial
Status: COMPLETED
Conditions: Intensive Care Units, Neonatal|Misadventures to Patients During Surgical and Medical Care|Catheter-related Bloodstream Infection (CRBSI) Nos|Quality of Healthcare|Ventilator Adverse Event|Nosocomial Pneumonia|Immature Newborn|Skin Lesion|Extravasation Injury|Nasal Injury|Intubation Complication|Medication Administered in Error|IV Catheter Nos Deep Venous Thrombosis
Interventions: BEHAVIORAL: Education program for NICU caregivers
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy/Safety Study to Explore a New Topical Formulation in Atopic Dermatitis
Status: WITHDRAWN
Conditions: Dermatitis, Atopic
Interventions: DEVICE: Phoenix (BAY81-2996)|DRUG: 1% Hydrocortison cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Using Virtual Reality for Patients With Gastrointestinal Disease
Status: UNKNOWN
Conditions: Gastrointestinal Disease|Inflammatory Bowel Diseases
Interventions: OTHER: HealthVoyager|OTHER: Standard Practice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Cannabis Effects on Driving-related Skills of Young Drivers
Status: COMPLETED
Conditions: Psychomotor Impairment
Interventions: DRUG: delta-9-tetrahydrocannabinol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Placebo and Active Controlled Study to Compare the Efficacy of Aspirin and Paracetamol in Treatment of Sore Throat Associated With a Common Cold
Status: COMPLETED
Conditions: Common Cold|Pharyngitis|Tonsillitis
Interventions: DRUG: Acetylsalicylic acid (Aspirin, BAYE4465)|DRUG: Paracetamol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Glutamate Emotion Memory Study
Status: RECRUITING
Conditions: Treatment Resistant Depression|Depression|Major Depressive Disorder
Interventions: DRUG: Ketamine Hydrochloride|OTHER: No intervention (placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Prolonged Emend in a Study (NYU 03-67) of Oxaliplatin and Topotecan in Previously Treated Ovarian Cancer
Status: WITHDRAWN
Conditions: Ovarian Cancer
Interventions: DRUG: Aprepitant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Calcaneal Low Dye Taping Plantar Fascial Stretching and Sham Taping in Football Players
Status: ACTIVE_NOT_RECRUITING
Conditions: Sports Physical Therapy
Interventions: OTHER: Low-dye taping|OTHER: Plantar fascia stretching|OTHER: sham taping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Techniques for Umbilical Reconstruction
Status: COMPLETED
Conditions: Umbilicoplasty
Interventions: PROCEDURE: Round Procedure Umbilicoplasty|PROCEDURE: Scarless" round procedure|PROCEDURE: "Inverted U" Procedure|PROCEDURE: "Inverted V"Procedure|PROCEDURE: "Y deepithelialized" Procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Observation Study of Patients With Non-Small Cell Lung Cancer and Esophageal Cancer Treated With Chemo-Radiation Followed by Surgery
Status: COMPLETED
Conditions: Lung Cancer|Esophageal Cancer
Interventions: DRUG: Carboplatin|DRUG: Paclitaxel|RADIATION: Radiation Therapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p