pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Comparison of Postoperative Outcome of Hepatectomy for Living Donors According to Three Different Incision
Status: COMPLETED
Conditions: Healthy Donors for Liver Transplantation
Interventions: PROCEDURE: hepatectomy conventional incision|PROCEDURE: hepatectomy midline incision|PROCEDURE: hepatectomy transverse incision
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Two Schedules of Infliximab Maintenance Therapy in Ankylosing Spondylitis
Status: COMPLETED
Conditions: Ankylosing Spondylitis
Interventions: DRUG: infliximab|DRUG: methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Structured Patient Education and Quality of Life of Elderly Patients With Diabetes Mellitus- a Prospective Study
Status: COMPLETED
Conditions: Impact of Structured DTTP on Quality of Life|Insulin Therapy|Metabolic Control|Psychological Aspects
Interventions: BEHAVIORAL: Structured diabetes teaching and treatment program
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Abaloparatide Added to Ongoing Denosumab vs Continued Denosumab Alone
Status: RECRUITING
Conditions: Osteoporosis, Postmenopausal
Interventions: DRUG: Denosumab Injection|DRUG: Abaloparatide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I/Ib Study of NK Expressing an Affinity-enhanced T-cell Receptor (TCR) Against the NY-ESO-1
Status: SUSPENDED
Conditions: Synovial Sarcoma|Myxoid/Round Cell Liposarcoma
Interventions: DRUG: Fludarabine phosphate|DRUG: NY-ESO-1 TCR/IL-15 NK|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of High Dose and Low Dose Dexamethasone in Preventing Post-Extubation Airway Obstruction in Adults
Status: UNKNOWN
Conditions: Airway Obstruction
Interventions: DRUG: dexamethasone (Oradexon, Nederland)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Sentinel Node Localization and Staging With Low Dose Superparamagnetic Iron Oxide
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer|Sentinel Lymph Node
Interventions: DRUG: Superparamagnetic Iron Oxide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low Field Magnetic Stimulation in Mood Disorders Using the LFMS Device
Status: COMPLETED
Conditions: Depression|Bipolar Depression|Major Depressive Disorder
Interventions: DEVICE: Low Field Magnetic Stimulation Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Pilot RCT on the Management of Term Prelabour Rupture of Membranes
Status: UNKNOWN
Conditions: Prelabour Rupture of Membranes at Term
Interventions: PROCEDURE: Expectant management|PROCEDURE: Minimal Vaginal examinations (only when necessary)|PROCEDURE: Active management|PROCEDURE: Routine vaginal examinations
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Velcade (Bortezomib) Consolidation After Transplant
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Thalidomide|DRUG: Bortezomib|DRUG: Cyclophosphamide|DRUG: Dexamethasone|DRUG: Prednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Botulinum Toxin as a Novel Treatment for Prevention of Post-Traumatic Elbow Stiffness
Status: COMPLETED
Conditions: Post Traumatic Stiffness
Interventions: DRUG: Botulinum Toxin Type A|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Exploratory Study of Effective Core Formula of Chinese Medicine to Treat Primary Insomnia
Status: UNKNOWN
Conditions: Primary Insomnia
Interventions: DRUG: Chinese herbal Medicine|OTHER: the dummy of a Chinese Medicine prescription
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Safety, Tolerability and Pharmacokinetics of OZ439 in Healthy Male and Female Subjects
Status: COMPLETED
Conditions: Malaria Falciparum|Malaria Vivax|Healthy Volunteers
Interventions: DRUG: OZ439 50mg API capsules|DRUG: OZ439 200mg API capsules|DRUG: OZ439 400mg aqueous dispersion|DRUG: OZ439 800mg aqueous dispersion|DRUG: OZ439 100mg API capsules|DRUG: OZ439 400mg API capsules|DRUG: OZ439 1600mg aqueous dispersion|DRUG: OZ439 800mg API capsules|DRUG: OZ439 1200mg API capsules|DRUG: Placebo|DRUG: OZ439 200mg aqueous dispersion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Sudden Deafness With Prednisone+Hyperbaric Oxygen and Prednisone+Somatosensory Stimulation
Status: UNKNOWN
Conditions: Hearing Loss, Sudden|Prednisone Acetate|Hyperbaric Oxygen|Somatic Stimulus
Interventions: COMBINATION_PRODUCT: Drugs and Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Prosocial Effects of MDMA
Status: COMPLETED
Conditions: MDMA ('Ecstasy')|Social Interaction
Interventions: DRUG: MDMA|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Effectiveness and Safety of LED Light Source System for Endoscope
Status: WITHDRAWN
Conditions: Laparoscopic Cholecystectomy
Interventions: DEVICE: LED light source system for endoscope|DEVICE: Pinpoint Endoscopic Fluorescence Imaging System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Protein Kinase C (PKC) Inhibitor-Diabetic Retinopathy Phase 3 Study
Status: COMPLETED
Conditions: Diabetic Retinopathy
Interventions: DRUG: ruboxistaurin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Vaginal Prasterone In Vaginal Atrophy In Breast Cancer Survivors
Status: COMPLETED
Conditions: Vulvar Atrophy|Breast Cancer|Genitourinary Syndrome of Menopause
Interventions: DRUG: Prasterone (DHEA), Micronized
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Clinical Recruitment of Patients With First-line Targeted Drug Resistance or Intolerance to Hepatocellular Cancer With PD-1 Inhibitor (Toripalimab,JS001) Detected on the NGS Platform Combined With Anlotinib
Status: UNKNOWN
Conditions: Hepatocellular Cancer
Interventions: DRUG: Anlotinib;Toripalimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: COmparison Between Continued Inpatient Treatment Versus Day Patient Treatment in Early Onset Anorexia Nervosa
Status: RECRUITING
Conditions: Early Onset Anorexia Nervosa
Interventions: OTHER: FTH then DH support|OTHER: standard care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: S0331: Imatinib Mesylate in Treating Patients With Metastatic or Unresectable Merkel Cell Cancer
Status: COMPLETED
Conditions: Recurrent Neuroendocrine Carcinoma of the Skin|Stage II Neuroendocrine Carcinoma of the Skin|Stage III Neuroendocrine Carcinoma of the Skin
Interventions: DRUG: imatinib mesylate|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase III Efficacy Study of the Symptomatic Treatment of Seasonal Allergic Rhinitis With Bilastine
Status: COMPLETED
Conditions: Seasonal Allergic Rhinitis
Interventions: DRUG: Bilastine|DRUG: Desloratadine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sanitation, Water, and Instruction in Face-washing for Trachoma I/II
Status: RECRUITING
Conditions: Trachoma
Interventions: BEHAVIORAL: Water, sanitation, and hygiene (WASH) intervention|BEHAVIORAL: Standard of care WASH intervention|DRUG: Azithromycin|DRUG: Tetracycline|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Biweekly Gemcitabine and Docetaxel as First Line Treatment for Advanced Disease in Elderly Non-Small Cell Lung Cancer (NSCLC) Patients
Status: UNKNOWN
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: Gemcitabine and Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EP4-receptor Antagonism and Prostaglandin E2 (PGE2) in a Human Headache Model
Status: COMPLETED
Conditions: Headache, Migraine
Interventions: DRUG: BGC20-1531
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating Drug-Drug Interaction (DDI) Between HSK3486 Injectable Emulsion and Voriconazole Tablets
Status: COMPLETED
Conditions: Anesthesia|Sedation
Interventions: DRUG: HSK3486|DRUG: voriconazole +HSK3486
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Family-centred E-health in Pediatric Weight Management: A Pilot Study
Status: COMPLETED
Conditions: Pediatric Obesity
Interventions: BEHAVIORAL: Communication through PHR outside clinic|BEHAVIORAL: Monitoring device in PHR|DEVICE: Physical activity and sleep monitor|OTHER: PHR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Dairy on Cognitive Performance in Children
Status: COMPLETED
Conditions: Children|Healthy
Interventions: OTHER: Fat-free milk|OTHER: Fat-free yogurt|OTHER: Low-fat cheese|OTHER: Fruit juice|OTHER: Snack skipping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Neoadjuvant or Adjuvant Systemic Therapy on Breast Cancers, Bone Marrow Cancer Cells, and Circulating Cancer Cells
Status: RECRUITING
Conditions: Breast Neoplasms
Interventions: PROCEDURE: Peripheral blood draw|PROCEDURE: Breast tissue collection|PROCEDURE: Bone marrow biopsy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety of Efficacy and Safety of Continued Iron Chelation Therapy In Poly-transfused Thalassemia Patients With Low Serum Ferritin (< 500 ng/ml)
Status: UNKNOWN
Conditions: Beta-thalassemia|Serum Ferritin|Iron Chelation Therapy
Interventions: DRUG: desferal, ferriprox, blood transfusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Management of Pasireotide-induced Hyperglycemia in Adult Patients With Cushing's Disease or Acromegaly
Status: COMPLETED
Conditions: Cushing's Disease|Acromegaly
Interventions: DRUG: Pasireotide s.c.|DRUG: Sitagliptin|DRUG: Liraglutide|DRUG: Insulin|DRUG: Pasireotide LAR|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of XL092 in Combination With Immuno-Oncology Agents in Subjects With Solid Tumors
Status: RECRUITING
Conditions: Renal Cell Carcinoma|Metastatic Castration-resistant Prostate Cancer|Urothelial Carcinoma|Solid Tumor|Hepatocellular Carcinoma|Non-small Cell Lung Cancer|Colorectal Cancer|Head and Neck Squamous Cell Carcinoma
Interventions: DRUG: XL092|DRUG: Nivolumab|DRUG: Ipilimumab|DRUG: Nivolumab|DRUG: Nivolumab|DRUG: Nivolumab + Relatlimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Umbilical Cord Blood Mononuclear Cell Transplant to Treat Chronic Spinal Cord Injury
Status: COMPLETED
Conditions: Spinal Cord Injuries
Interventions: BIOLOGICAL: Umbilical Cord Blood Mononuclear Cell|BIOLOGICAL: Methylprednisolone|DRUG: Lithium Carbonate Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Open-label, Randomized, Crossover Study to Assess PK of Pregabalin
Status: COMPLETED
Conditions: Peripheral Nueropathy Pain
Interventions: DRUG: YHD1119|DRUG: Lyrica
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dorsal vs. Ventral Buccal Graft Dorsal vs. Ventral Buccal Graft
Status: TERMINATED
Conditions: Urethral Stricture
Interventions: PROCEDURE: Urethroplasty with buccal mucosa graft|PROCEDURE: Ventral Buccal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Conor Cobalt Chromium Reservoir Based Stent With Sirolimus Elution in Native Coronary Artery Lesions
Status: TERMINATED
Conditions: Coronary Disease
Interventions: DEVICE: NEVO™ Sirolimus-eluting Coronary Stent System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Probiotic Lactobacilli for the Treatment of Lactational Mastitis
Status: COMPLETED
Conditions: Mastitis
Interventions: BIOLOGICAL: Lactobacillus salivarius HN6|BIOLOGICAL: Lactobacillus reuteri CR20|BIOLOGICAL: Lactobacillus fermentum LC40|DRUG: Beta-lactam antibiotic
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Trastuzumab Emtansine in Patients With HER2-Positive Metastatic Breast Cancer and Normal or Reduced Hepatic Function
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: trastuzumab emtansine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Sodium Heparin in Prophylaxis of Venous Thromboembolism in Surgical Patients
Status: WITHDRAWN
Conditions: Venous Thromboembolism
Interventions: BIOLOGICAL: heparin sodium - Blausiegel|BIOLOGICAL: Heparin sodium - APP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Exercise for Brain Regeneration in Epilepsy
Status: RECRUITING
Conditions: Temporal Lobe Epilepsy
Interventions: OTHER: High-Impact Aerobic Exercise|OTHER: Low-Impact Aerobic Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Phase I Study of Oral COL-3 (NSC-683551), a Matrix Metalloproteinase Inhibitor, in Patients With Refractory Metastatic Cancer
Status: COMPLETED
Conditions: Lymphoma|Melanoma|Neoplasm Metastasis|Renal Cell Carcinoma
Interventions: DRUG: COL-3
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Nijmegen Antihypertensive Management Improvement Study
Status: COMPLETED
Conditions: Primary Hypertension
Interventions: DRUG: hydrochlorothiazide|DRUG: valsartan, 80 mg once-a-day
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Analysis of Snore Sound Following Minimal Invasive Surgery in Sleep-disordered Breathing Patients
Status: COMPLETED
Conditions: Primary Snoring|Obstructive Sleep Apnea
Interventions: DEVICE: Pillar implant|DEVICE: Radiofrequency
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Health and Energy Through Active Living Every Day (HEALED) After Cancer Pilot Intervention for Cancer Survivors
Status: UNKNOWN
Conditions: Cancer|Quality of Life|Fatigue
Interventions: BEHAVIORAL: Physical activity
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pembrolizumab and EDP1503 in Advanced Melanoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Melanoma (Skin)|Melanoma
Interventions: DRUG: Pembrolizumab|BIOLOGICAL: EDP1503
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adoptive Transfer of Tumor Infiltrating Lymphocytes for Biliary Tract Cancers
Status: RECRUITING
Conditions: Biliary Tract Cancer|Cholangiocarcinoma|Biliary Tract Neoplasms
Interventions: BIOLOGICAL: Tumor Infiltrating Lymphocytes (TIL)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Tolerability of an Antiretroviral Bi-Therapy in HIV Infected Patients With Multidrug Resistance
Status: TERMINATED
Conditions: HIV Infections
Interventions: DRUG: Indinavir|DRUG: Lamivudine|DRUG: Ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transluminal Flexible Endoscopic Procedure in Foregut and Urologic Surgery
Status: COMPLETED
Conditions: Gastric Foreign Body, Nos|Disorder of Abdomen (Disorder)|Foreign Body in Esophagus|Prostatic Diseases|Disease of Small Intestine
Interventions: PROCEDURE: Natural Orifice Transluminal Endoscopic Surgery (NOTES)|PROCEDURE: Natural Orifice Translumenal Endoscopic Surgery (NOTES)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Predictive Value of Intraoperative Indocyanine Green Clearance Test After Partially Blood Flow Blocking in Postoperative Liver Reserve
Status: UNKNOWN
Conditions: Predictive Value of ICG Clearance Measurement During Selective Hepatic Vascular Trial Clamping on Remnant Liver Function After Anatomic Liver Resection
Interventions: DIAGNOSTIC_TEST: Indocynine green clearance test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Treatment of Obesity and Binge Eating: Behavioral Weight Loss Versus Stepped Care
Status: COMPLETED
Conditions: Obesity|Binge Eating
Interventions: BEHAVIORAL: Behavioral Weight Loss|BEHAVIORAL: Behavioral Weight Loss + Guided self-help Cognitive-behavioral Therapy|DRUG: Placebo|DRUG: Sibutramine/Orlistat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of ITI-1284 as an Adjunctive Treatment in Patients With Generalized Anxiety Disorder
Status: RECRUITING
Conditions: Generalized Anxiety Disorder
Interventions: DRUG: ITI-1284 10 mg|DRUG: ITI-1284 20 mg|DRUG: Placbo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Endoscopic Management of Non-anastomotic Biliary Strictures Following Liver Transplantation.
Status: RECRUITING
Conditions: Liver Transplant Disorder|Ischemic Cholangiopathy|Non-anastomotic Biliary Stricture|Biliary Stricture|Biliary Stents (Plastic)
Interventions: PROCEDURE: ERCP
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Anatomical Resection of Liver MetAstases iN patIents With RAS-mutated Colorectal Cancer
Status: RECRUITING
Conditions: Colorectal Liver Metastasis
Interventions: PROCEDURE: Resection of colorectal liver metastases
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Probiotic Supplementation on Markers of Muscle Damage and Performance Following Exercise Induced Muscle Damage
Status: COMPLETED
Conditions: Probiotics
Interventions: DIETARY_SUPPLEMENT: Lactic acid bacteria and bifidobacteria|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: The Effect of Laughter Therapy on Students in the COVID-19 Pandemic
Status: UNKNOWN
Conditions: Laughter Yoga|Anxiety|Life Satisfaction|Psychological Well-being|COVID-19
Interventions: OTHER: Laughter Theraphy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Do Traditional or Flavored Tongue Depressors Make for Easier Posterior Oropharynx Exams in Pediatric Patients
Status: COMPLETED
Conditions: Oropharynx
Interventions: DEVICE: Grape flavored Puritan Junior tongue depressor|DEVICE: Traditional unflavored Puritan Regular Tongue Depressor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Improving Patient Understanding of Preeclampsia
Status: COMPLETED
Conditions: Preeclampsia
Interventions: BEHAVIORAL: ACOG education pamphlet on preeclampsia|BEHAVIORAL: Preeclampsia education tool
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The PREHAAAB Trial: Multimodal Prehabilitation for Patients Awaiting Open Abdominal Aortic Aneurysm Repair
Status: NOT_YET_RECRUITING
Conditions: Abdominal Aortic Aneurysm
Interventions: BEHAVIORAL: Multimodal Prehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Safety, Tolerability and Pharmacokinetics of AZD5055 in Japanese and Chinese Healthy Volunteers..
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DRUG: AZD5055|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Exploration of High Frequency Otoacoustic Emissions and Developmental Language Disorders
Status: NOT_YET_RECRUITING
Conditions: Language Development Disorders
Interventions: DIAGNOSTIC_TEST: acoustic otoemisions|DIAGNOSTIC_TEST: Otoscopy|DIAGNOSTIC_TEST: Audiometry|DIAGNOSTIC_TEST: Tympanometry
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Maintenance ElectroConvulsive Therapy in Clozapine RESISTant Schizophrenia - the MECT-RESIST Trial
Status: NOT_YET_RECRUITING
Conditions: Schizophrenia|Treatment Resistant Schizophrenia
Interventions: DEVICE: maintenance electroconvulsive therapy (mECT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of FiO2 Titration Guided by the Oxygen Reserve Index in Preventing Hyperoxia.
Status: COMPLETED
Conditions: Hyperoxia|Complication
Interventions: PROCEDURE: Titration of fraction of inspired oxygen (FiO2) guided by ORI and oxygen saturation|PROCEDURE: SpO2 (oxygen saturation)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Anticoagulation and Inferior Vena Cava Filters in Cancer Patients With a Venous Thromboembolism
Status: TERMINATED
Conditions: Cancer|Thromboembolism
Interventions: DRUG: Arixtra alone|DEVICE: Arixtra + filter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Activity Dependent Rehabilitation Model to Improve Bone and Muscle Outcomes
Status: UNKNOWN
Conditions: Disuse Osteoporosis|Atrophy, Disuse|Nervous System|Structural; Marker|Skeletal Muscle Hypertrophy
Interventions: OTHER: Electrical Stimulation|OTHER: Stand Retraining with Body Weight Support (BWS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Omega-3 Polyunsaturated Fatty Acids in the Treatment and Prevention of Relapse of Bipolar Disorder
Status: COMPLETED
Conditions: Bipolar Disorder
Interventions: DIETARY_SUPPLEMENT: n-3 fatty acids|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Topical Simvastatin Versus Topical Steroid in Treatment of Alopecia Areata
Status: NOT_YET_RECRUITING
Conditions: Alopecia Areata
Interventions: DRUG: Simvastatin|DRUG: Mometasone Furoate|PROCEDURE: Fractional CO2 laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non-invasive Measurement of Hemoglobin Concentration With Pulse Co-oximetry
Status: COMPLETED
Conditions: Elective Hepatic Resection
Interventions: BIOLOGICAL: Hemoglobin determination + NaCl 0.9% bolus|BIOLOGICAL: hemoglobin determination + Venofundin bolus
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Clinical Study to Evaluate the Use of a Cryopreserved Formulation of OTL-103 in Subjects With Wiskott-Aldrich Syndrome
Status: ACTIVE_NOT_RECRUITING
Conditions: Wiskott-Aldrich Syndrome
Interventions: GENETIC: OTL-103
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Erlotinib, Docetaxel, and Radiation Therapy in Treating Patients With Locally Advanced Head and Neck Cancer
Status: COMPLETED
Conditions: Metastatic Squamous Neck Cancer With Occult Primary Squamous Cell Carcinoma|Stage III Squamous Cell Carcinoma of the Hypopharynx|Stage III Squamous Cell Carcinoma of the Larynx|Stage III Squamous Cell Carcinoma of the Lip and Oral Cavity|Stage III Squamous Cell Carcinoma of the Nasopharynx|Stage III Squamous Cell Carcinoma of the Oropharynx|Stage III Verrucous Carcinoma of the Larynx|Stage III Verrucous Carcinoma of the Oral Cavity|Stage IV Squamous Cell Carcinoma of the Hypopharynx|Stage IV Squamous Cell Carcinoma of the Nasopharynx|Stage IVA Squamous Cell Carcinoma of the Larynx|Stage IVA Squamous Cell Carcinoma of the Lip and Oral Cavity|Stage IVA Squamous Cell Carcinoma of the Oropharynx|Stage IVA Verrucous Carcinoma of the Larynx|Stage IVA Verrucous Carcinoma of the Oral Cavity|Stage IVB Squamous Cell Carcinoma of the Larynx|Stage IVB Squamous Cell Carcinoma of the Lip and Oral Cavity|Stage IVB Squamous Cell Carcinoma of the Oropharynx|Stage IVB Verrucous Carcinoma of the Larynx|Stage IVB Verrucous Carcinoma of the Oral Cavity|Stage IVC Squamous Cell Carcinoma of the Larynx|Stage IVC Squamous Cell Carcinoma of the Lip and Oral Cavity|Stage IVC Squamous Cell Carcinoma of the Oropharynx|Stage IVC Verrucous Carcinoma of the Larynx|Stage IVC Verrucous Carcinoma of the Oral Cavity|Tongue Cancer|Untreated Metastatic Squamous Neck Cancer With Occult Primary
Interventions: DRUG: erlotinib hydrochloride|DRUG: docetaxel|RADIATION: radiation therapy|PROCEDURE: therapeutic conventional surgery|OTHER: laboratory biomarker analysis|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Effectiveness Study of Spironolactone Versus Doxycycline for Acne
Status: RECRUITING
Conditions: Acne
Interventions: DRUG: Spironolactone|DRUG: Doxycycline Hyclate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pain Patch Versus Injections in the Treatment of Pain Associated With Shoulder Impingement Syndrome
Status: UNKNOWN
Conditions: Shoulder Pain
Interventions: DRUG: Synera® (lidocaine 70 mg and tetracaine 70 mg) topical patch|DRUG: Triamcinolone Acetonide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Sustained Natural Apophyseal Glides Combined With Kinesiotaping in Patients With Chronic Mechanical Neck Pain: A Randomised Controlled Trial
Status: RECRUITING
Conditions: Neck Pain
Interventions: PROCEDURE: Sustained Natural Apophyseal Glides|PROCEDURE: Kinesiotaping|PROCEDURE: Conventional Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Study to Evaluate the Efficacy and Safety of VIR-2482 for the Prevention of Illness Due to Influenza A
Status: TERMINATED
Conditions: Influenza A
Interventions: BIOLOGICAL: VIR-2482 (dose 1)|BIOLOGICAL: VIR-2482 (dose 2)|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: GUARDIAN (NCT04884802) Sub-study, Etomidate vs Propofol
Status: RECRUITING
Conditions: Major Surgery
Interventions: PROCEDURE: Routine blood pressure control|PROCEDURE: Tight blood pressure control|DRUG: Etomidate|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Radiofrequency Ablation Using Octopus Electrodes for Treatment of Focal Liver Malignancies: Follow-up Study
Status: COMPLETED
Conditions: Hepatocellular Carcinoma
Interventions: DEVICE: Separable clustered electrodes
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Dual Therapies in the First-line Treatment of Helicobacter Pylori Infection （SHARE2301）
Status: RECRUITING
Conditions: Helicobacter Pylori Infection
Interventions: DRUG: Tegoprazan|DRUG: Amoxicillin|DRUG: Esomeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vitamin D Supplementation for the Prevention of Acute Respiratory Tract Infections
Status: COMPLETED
Conditions: Respiratory Tract Infections
Interventions: DIETARY_SUPPLEMENT: vitamin D|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: SPD489 in Adults Aged 18-55 Years With Moderate to Severe Binge Eating Disorder
Status: COMPLETED
Conditions: Binge Eating Disorder
Interventions: DRUG: SPD489 (Lisdexamfetamine dimesylate)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Abiraterone Acetate (JNJ-212082) and Prednisolone in Patients With Advanced Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: Abiraterone acetate|DRUG: Prednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Microbiome as a Target for Precision Medicine in Atherosclerosis
Status: COMPLETED
Conditions: Acute Coronary Syndrome|Atherosclerosis
Interventions: PROCEDURE: Assessment of the atherosclerotic plaque in a moderate lession.|GENETIC: Gene variants in atherosclerosis|OTHER: Microbiota analysis|OTHER: Immunological analysis|OTHER: Clinical evaluation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Plantar Fasciitis and the Use of Orthotics as Treatment
Status: COMPLETED
Conditions: Plantar Fascitis
Interventions: DEVICE: Aetrex L420 Compete Orthotic|DEVICE: Aetrex indoor comfort sandal with built-in arch support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cardiovascular and Cognitive Implications of Central Disorders of Hypersomnolence and Their Treatments
Status: ENROLLING_BY_INVITATION
Conditions: Narcolepsy|Idiopathic Hypersomnia
Interventions: DIAGNOSTIC_TEST: 24-hour Ambulatory Blood Pressure Monitoring|DIAGNOSTIC_TEST: Oculo-Cognitive Addition Test (OCAT)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy of Cardiac Rehab for Patients With Peripheral Artery Disease Versus Patients With Coronary Artery Disease
Status: WITHDRAWN
Conditions: Peripheral Arterial Disease|Coronary Artery Disease|Vascular Diseases
Interventions: OTHER: Cardiac Rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: SmartHMD for Improved Mobility
Status: RECRUITING
Conditions: Low Vision|Orientation|Mobility Limitation|Navigation, Spatial|Visual Impairment
Interventions: DEVICE: No HMD used|DEVICE: HMD worn but not active|DEVICE: HMD worn and active
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Visibility of Site Marking for Surgical Time Out With Two Different Skin Preparation Solutions
Status: COMPLETED
Conditions: Arthroplasty, Replacement, Hip
Interventions: DRUG: CHG 2% w/v and IPA 70% v/v|DRUG: Iodophor 0.7% and IPA 74% w/w
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Blue Light in the Treatment of Inflammatory Skin Diseases
Status: COMPLETED
Conditions: Atopic Dermatitis|Psoriasis Vulgaris|Eczema|Pruritus
Interventions: DEVICE: Full Body Blue GEN 1.0 device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial Investigating the Safety, Tolerability, Availability and Distribution in the Body of Once-weekly Long-acting Growth Hormone (Somapacitan) Compared to Once Daily Norditropin NordiFlex® in Adults With Growth Hormone Deficiency
Status: COMPLETED
Conditions: Growth Hormone Disorder|Adult Growth Hormone Deficiency
Interventions: DRUG: somapacitan|DRUG: Norditropin NordiFlex®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Low and High Tidal Volumes in Acute Spinal Cord Injury
Status: ACTIVE_NOT_RECRUITING
Conditions: Spinal Cord Injuries
Interventions: DEVICE: High tidal volume|DEVICE: Low tidal volume
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Acupressure and Halogen Light Stimulation on Nonstress Testing and Pregnant Anxiety
Status: UNKNOWN
Conditions: Acupressure
Interventions: OTHER: Acupressure|OTHER: Halojen ışık|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of Motor Learning on Balance, Mobility and Performance of Activities of Daily Living Among Post-Stroke Patients
Status: UNKNOWN
Conditions: Stroke
Interventions: OTHER: Study Group (Motor relearning program)|OTHER: Control Group (Conventional physical therapy program)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Safety, Tolerability and Efficacy of Trametinib (SNR1611) in Patients With Amyotrophic Lateral Sclerosis (ALS)
Status: TERMINATED
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DRUG: Trametinib (0.5 mg)|DRUG: Trametinib (1 mg)|DRUG: Riluzole (100 mg)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Platelet Reactivity in Patients on a Thienopyridine and Awaiting Coronary Artery Bypass Grafting
Status: COMPLETED
Conditions: Complication of Coronary Artery Bypass Graft|Peri-operative Hemorrhage or Hematoma|Post Operative Bleeding
Interventions: OTHER: Platelet reactivity assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Feasibility Study for Ultrasound-Guided Interstitial Brachytherapy for Gynecological CancersV2
Status: COMPLETED
Conditions: Gynecologic Cancer
Interventions: DEVICE: Interstitial and intracavitary brachytherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study of the Safety and Activity of Lenvatinib (E7080) in Subjects With KIF5B-RET-Positive Adenocarcinoma of the Lung
Status: COMPLETED
Conditions: KIF5B-RET-Positive Adenocarcinoma of the Lung
Interventions: DRUG: Lenvatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Luteinizing Hormone-releasing Hormone Analogue and Enzalutamide +/- Zoledronic Acid in Prostate Cancer Patients
Status: COMPLETED
Conditions: Prostate Cancer|Bone Metastases
Interventions: DRUG: Zoledronic Acid|DRUG: Enzalutamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Will Elevated Left Ventricle Filling Pressures Decrease by a Group Exercise Program in Patients With Hypertrophic CardioMyopathy?
Status: COMPLETED
Conditions: Hypertrophic Cardiomyopathy
Interventions: OTHER: Exercise training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Combination Chemotherapy and Bevacizumab Before Surgery and Radiolabeled Monoclonal Antibody Therapy in Treating Liver Metastases in Patients With Metastatic Colorectal Cancer
Status: TERMINATED
Conditions: Liver Metastases|Recurrent Colon Cancer|Recurrent Rectal Cancer|Stage IVA Colon Cancer|Stage IVA Rectal Cancer|Stage IVB Colon Cancer|Stage IVB Rectal Cancer
Interventions: DRUG: oxaliplatin|DRUG: leucovorin calcium|DRUG: fluorouracil|BIOLOGICAL: bevacizumab|RADIATION: yttrium Y 90 DOTA anti-CEA monoclonal antibody M5A|OTHER: laboratory biomarker analysis|OTHER: pharmacological study|DRUG: irinotecan hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Bucelipase Alfa (BSSL) in Patients With Cystic Fibrosis and Pancreatic Insufficiency
Status: COMPLETED
Conditions: Cystic Fibrosis|Exocrine Pancreatic Insufficiency
Interventions: DRUG: rhBSSL
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: mHealth Facilitated Intervention to Improve HIV Pre-Exposure Prophylaxis Adherence
Status: WITHDRAWN
Conditions: Pre-Exposure Prophylaxis|Telemedicine|Medication Adherence
Interventions: BEHAVIORAL: Face-to-Face PrEP Adherence Intervention Based on LifeSteps|BEHAVIORAL: Adherence Coaching Facilitated by Carium Adherence App
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of Cord Blood Mononuclear Cells on Treatment of Hormone-resistant or Hormone-dependent Ulcerative Colitis
Status: UNKNOWN
Conditions: Ulcerative Colitis
Interventions: DRUG: Prednisone|DRUG: Azathioprine|DRUG: Adalimumab|BIOLOGICAL: umbilical cord blood mononuclear cells
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effects of Cannabidiol (CBD) Compared to Delta-9-Tetrahydrocannabinol (THC) and Alprazolam
Status: COMPLETED
Conditions: Cannabis Use Disorder
Interventions: DRUG: THC|DRUG: Alprazolam|DRUG: Placebo oral capsule|DRUG: CBD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study Evaluating the Efficacy and Safety of Crenezumab Versus Placebo in Participants With Prodromal to Mild Alzheimer's Disease (AD).
Status: TERMINATED
Conditions: Alzheimer's Disease
Interventions: DRUG: Crenezumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Proof of Concept and Dose-finding Study of XXB750 in Patients With Heart Failure
Status: RECRUITING
Conditions: Heart Failure
Interventions: BIOLOGICAL: Placebo|BIOLOGICAL: XXB750 Low dose|BIOLOGICAL: XXB750 Medium Dose|BIOLOGICAL: XXB750 High Dose|DRUG: Sacubitril/valsartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dose-finding Study to Assess the Efficacy, Safety and Tolerability of Tobramycin Inhalation Powder in Patients With Non-Cystic Fibrosis Bronchiectasis and Pulmonary P. Aeruginosa Infection
Status: COMPLETED
Conditions: Non-cystic Fibrosis Bronchiectasis
Interventions: DRUG: TIP|DRUG: TIP and placebo|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Exploratory Study for Allergy Relief Onset
Status: TERMINATED
Conditions: Rhinitis, Allergic
Interventions: DRUG: Chlorpheniramine maleate (BAY X002134)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Drainage Fluid Biomarkers and Anastomotic Leakage in Colorectal Surgery. A Monocentric Prospective Observational Study
Status: COMPLETED
Conditions: Anastomotic Leakage
Interventions: PROCEDURE: Elective or emergency colorectal surgery for cancer, diverticular disease, inflammatory bowel-disease or reversal of Hartmann's procedure
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Real-World Outcomes of Nivolumab+Ipilimumab and Pembrolizumab+Lenvatinib Among US Advanced Renal Cell Carcinoma (aRCC) Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Renal Cell Carcinoma (aRCC)
Interventions: COMBINATION_PRODUCT: Nivolumab + Ipilimumab combination therapy|COMBINATION_PRODUCT: Pembrolizumab + Lenvatinib combination therapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pilot Study of Autologous T-cells in Patients With Metastatic Pancreatic Cancer
Status: TERMINATED
Conditions: Pancreatic Cancer
Interventions: BIOLOGICAL: CART-meso-19 T cells|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ParkinStim: Transcranial Direct Current Stimulation for Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: PROCEDURE: Active tDCS|PROCEDURE: Sham tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Safety and Efficacy Study of JUVÉDERM® VOLIFT® With Lidocaine and Restylane® for Nasolabial Folds in Chinese Adults
Status: COMPLETED
Conditions: Nasolabial Fold
Interventions: DEVICE: JUVÉDERM® VOLIFT® with Lidocaine|DEVICE: Restylane®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity Study of Hib-MenCY-TT Vaccine Compared to Licensed Hib Conjugate Vaccine
Status: COMPLETED
Conditions: Haemophilus Influenzae Type b|Neisseria Meningitidis
Interventions: BIOLOGICAL: GSK Biologicals' Haemophilus influenzae type b and Neisseria meningitidis 792014 vaccine|BIOLOGICAL: ActHIB|BIOLOGICAL: PedvaxHIB|BIOLOGICAL: Pediarix|BIOLOGICAL: Prevnar|BIOLOGICAL: M-M-R II|BIOLOGICAL: Varivax
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Multiple Rising Doses of BI 187004 in Patients With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Placebo|DRUG: BI 187004|DRUG: BI 187004|DRUG: BI 187004|DRUG: BI 187004|DRUG: BI 187004|DRUG: BI 187004|DRUG: BI 187004
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: The Response Study of Yt90-Zevalin in Patients With Diffuse Large B-cell Lymphoma After 6 Cycles of CHOP
Status: COMPLETED
Conditions: Diffuse Large B-cell Lymphoma
Interventions: DRUG: chemotherapy followed by Zevalin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT