pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Clinical Study Designed to Evaluate the Effect of CimetrA in Patients Diagnosed With COVID-19
Status: UNKNOWN
Conditions: Corona Virus Infection|Covid19|SARS-CoV Infection
Interventions: DRUG: Placebo administration|DIAGNOSTIC_TEST: Confirm SARS-CoV-2 infection|PROCEDURE: Physical Examination|PROCEDURE: Vital Signs|DIAGNOSTIC_TEST: Hematology blood test|DIAGNOSTIC_TEST: Biochemistry blood test|OTHER: NEWS score|DIAGNOSTIC_TEST: PK test|DIAGNOSTIC_TEST: blood test for inflammatory markers|DIAGNOSTIC_TEST: D-dimer test|OTHER: VAS scale|DIAGNOSTIC_TEST: Urine pregnancy test for women of childbearing potential|PROCEDURE: ECG|OTHER: COVID-19-Impact on Quality of Life Questionnaire|DRUG: CimetrA-1|DRUG: CimetrA-2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Virtual Reality Exercise Versus Aerobic Training on Performance and Endurance in Physical Therapy Students
Status: RECRUITING
Conditions: Cardiorespiratory Fitness or Endurance
Interventions: OTHER: group (A ) study group :virtual reality cycling by fully immersive Head-Mounted Display virtual reality (Oculus Quest virtual reality (VR) headset with hand controller).
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Transcranial Direct Current Stimulation (tDCS) on Persistent Auditory Verbal Hallucinations in Schizophrenia
Status: UNKNOWN
Conditions: Auditory Hallucination, Verbal
Interventions: DEVICE: Transcranial direct current stimulation (tDCS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Aldesleukin With or Without Vaccine Therapy in Treating Patients With Locally Advanced or Metastatic Melanoma
Status: COMPLETED
Conditions: Recurrent Melanoma|Stage IIIA Skin Melanoma|Stage IIIB Skin Melanoma|Stage IIIC Skin Melanoma|Stage IV Skin Melanoma
Interventions: BIOLOGICAL: Aldesleukin|BIOLOGICAL: gp100 Antigen|DRUG: Montanide ISA 51 VG|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Strategies to Increase HIV Testing, Linkages to Care, and Male Circumcision in Africa
Status: COMPLETED
Conditions: HIV
Interventions: OTHER: POC CD4 Testing|OTHER: CD4 Referral|BEHAVIORAL: Lay Counselor Follow-up|BEHAVIORAL: Clinic Accompaniment|BEHAVIORAL: Clinic Referral|BEHAVIORAL: SMS Reminder|BEHAVIORAL: Circumcision Promotion|OTHER: POC VL|OTHER: Laboratory based VL assay
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Intervention to Expand Opioid Use Disorder Treatment Pharmacotherapy Prescribers
Status: COMPLETED
Conditions: Opioid-use Disorder
Interventions: BEHAVIORAL: Prescriber Recruitment Bundle (PRB)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Reducing Plasma Glucose Effect of Cinnamon in Type 2 Diabetic Patients in the Municipality of Comasagua
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DIETARY_SUPPLEMENT: Cinnamon|DIETARY_SUPPLEMENT: Wheat Flour
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Use of Mirror Image on Radiation Exposure During Fluoroscopically Guided Transforaminal Epidural Injection
Status: COMPLETED
Conditions: Lumbar Radiculopathy Due to Spinal Nerve Compression
Interventions: PROCEDURE: Fluoroscopically Guided Lumbar Transforaminal Epidural Injections|PROCEDURE: conventional manner
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Trimetazidine in Myocardial Injury After Percutaneous Coronary Intervention in Patients With Angina and Diabetes
Status: UNKNOWN
Conditions: Diabetes Mellitus|Angina, Unstable
Interventions: DRUG: trimetazidine|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety, Tolerability, Pharmacokinetics and Pharmacodynamics Study of Pegylated-Somatropin in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Pegylated-Somatropin|DRUG: YPEG-Somatropin|DRUG: YPEG-Somatropin|DRUG: YPEG-Somatropin|DRUG: YPEG-Somatropin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Comparison Between Reciproc and Oneshape Systems
Status: UNKNOWN
Conditions: Pulpitis
Interventions: PROCEDURE: Reciproc single file system|PROCEDURE: One Shape single file system|DEVICE: X-smart Plus, Dentsply Maillefer, Ballaigues, Switzerland
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Manufacturing of Allogeneic Adipose Tissue-derived Mesenchymal Stromal Cells for Treatment of Severe Systemic Sclerosis
Status: NOT_YET_RECRUITING
Conditions: Mesenchymal Stromal Cell|Systemic Sclerosis
Interventions: OTHER: Adipose tissue harvesting
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Efficacy and Safety of Two Pharmacologic Strategies on Neurocognitive Impairment in HIV Infection. The TRIANT-TE Study
Status: COMPLETED
Conditions: Neurocognitive Disturbance|HIV Infection
Interventions: DRUG: Lithium|DRUG: Rivastigmine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study To Test The Safety, Amount And Effects Of PF-06282999 In Healthy Overweight Adults And A Study To Test The Effects Of PF-06282999 On The Amount Of The Approved Drug, Midazolam, In Healthy Adults
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: PF-06282999|DRUG: Placebo|DRUG: PF-06282999|DRUG: Placebo|DRUG: PF-06282999|DRUG: Placebo|DRUG: PF-06282999|DRUG: Placebo|DRUG: PF-06282999|DRUG: Placebo|DRUG: midazolam|DRUG: PF-06282999|DRUG: midazolam|DRUG: PF-06282999
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: STAR Cape+BKM120 MBC With Brain Met
Status: COMPLETED
Conditions: Brain Metastases|Breast Cancer|Metastatic Breast Cancer
Interventions: DRUG: BKM120|DRUG: capecitabine|DRUG: Trastuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Educational Intervention for the Development of Professionals Skills in Family Medicine and Community Nursing Residents
Status: UNKNOWN
Conditions: Empathy|Burnout, Professional
Interventions: BEHAVIORAL: Face-to-face|BEHAVIORAL: Online
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Artemisinin-Based Combination Therapy: Clinical Trials in Cameroon
Status: COMPLETED
Conditions: Malaria
Interventions: DRUG: 1. Artemether-Lumefantrine (AL)|DRUG: 2. Amodiaquine-Artesunate (AQ-AS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Distalization and Functional Appliance Therapy
Status: COMPLETED
Conditions: Mandibular Retrognathism
Interventions: DEVICE: Herbst Appliance|DEVICE: Distal Jet Appliance
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Omeprazole Delayed Release (DR) Capsules Bioequivalence Study of Dr. Reddys Under Fed Condition
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Omeprazole|DEVICE: Prilosec® 40 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study To Assess The Safety And Effectiveness Of Prevenar In Chinese Children Who Have Not Previously Received A Vaccine Against Pneumococcal Bacteria
Status: COMPLETED
Conditions: Pneumococcal Infections
Interventions: BIOLOGICAL: Prevenar|BIOLOGICAL: Prevenar|BIOLOGICAL: Prevenar|BIOLOGICAL: Prevenar
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effects of Different Health Qigong Routines on CS Among Chinese College Students
Status: RECRUITING
Conditions: Neck Pain|Neck Disorder|Cervical Spondylosis
Interventions: BEHAVIORAL: Health Qigong·Yijinjing|BEHAVIORAL: Health Qigong·Wuqinxi|BEHAVIORAL: Health Qigong·Baduanjin|BEHAVIORAL: Walking
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Whole Body Vibration Exercise Training for Institutionalized Elderly
Status: UNKNOWN
Conditions: Geriatric Disorder
Interventions: DEVICE: Whole body vibration|BEHAVIORAL: Conventional exercise|BEHAVIORAL: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Omega-3 EPA/DHA for Soldiers at Risk for Mood Disorders
Status: UNKNOWN
Conditions: Mood Disorders|Depression|Combat Disorders|Stress Disorders
Interventions: DRUG: Lovaza, omega-3 fatty acid ethyl ester|DRUG: Placebo, visually identical to Lovaza
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A 12-Week Crossover Study to Assess the Efficacy, Safety and Tolerability of L1-79 in Subjects Aged 12-21 Years With Autism Spectrum Disorder
Status: COMPLETED
Conditions: Autism Spectrum Disorder|Autism
Interventions: DRUG: L1-79
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of a Steroid/Antibiotic Combination Eyedrop to Treat Non-Bacterial Blepharitis
Status: COMPLETED
Conditions: Blepharitis
Interventions: DRUG: ISV-502 (1.0% azithromycin and 0.1% dexamethasone combined)|DRUG: Azasite|DRUG: Dexamethasone|OTHER: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Multi-Site Study to Evaluate the Safety and Effect of Study Drug on Participants With Rheumatoid Arthritis
Status: COMPLETED
Conditions: Arthritis, Rheumatoid
Interventions: DRUG: LY2127399|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Laparoscopic Microwave Ablation and Portal Vein Ligation for Staged Hepatectomy (LAPS)
Status: UNKNOWN
Conditions: Liver Tumors
Interventions: PROCEDURE: VLS ablation/portal ligation/hepatectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prehospital Triage of Patients With Severe Shortness of Breath Using Biomarkers
Status: COMPLETED
Conditions: Dyspnea
Interventions: OTHER: Supplementary NT-proBNP measurement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: H.O.P.E: Helping Ovarian Cancer Patients Cope
Status: COMPLETED
Conditions: Platinum-resistant Ovarian Cancer|Recurrent Ovarian Cancer|Palliative Care
Interventions: OTHER: Structured Palliative Care|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Influence of 5-Aminosalicylates on Thiopurine Metabolite Levels
Status: COMPLETED
Conditions: Crohn's Disease|Ulcerative Colitis|Inflammatory Bowel Disease
Interventions: DRUG: 5-aminosalicylate (Pentasa, Ferring)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Gemcitabine (GFF) in Patients With Pancreatic Cancer
Status: COMPLETED
Conditions: Metastatic Pancreatic Cancer
Interventions: DRUG: gemcitabine, folinic acid, 5-FU
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anhidrotic Area and Safety of MEDITOXIN in Healthy Male Valunteers
Status: COMPLETED
Conditions: Anhidrotic Area|Hyperhidrosis
Interventions: DRUG: Meditoxin|DRUG: Botox
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Effect of Muscle Relaxation Reversal on the Success Rate of Motor Evoked Potential Recording
Status: COMPLETED
Conditions: Sugammadex|Motor Evoked Potentials
Interventions: DRUG: Sugammadex|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Laryngeal Mask Ambu Aura Once vs. Supreme in Children
Status: WITHDRAWN
Conditions: Apnea
Interventions: DEVICE: laryngeal mask Ambu AuraOnce|DEVICE: laryngeal mask LMA Supreme
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study of Duvelisib in Combination With Rituximab vs Rituximab in Subjects With Previously Treated Follicular Lymphoma
Status: TERMINATED
Conditions: Follicular Lymphoma
Interventions: DRUG: Duvelisib|DRUG: Placebo|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Sintilimab Plus Bevacizumab in Metastatic Nasopharyngeal Carcinoma After Failure of Platinum-based Chemotherapy: An Open-label Phase II Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Nasopharyngeal Carcinoma|Chemotherapy Effect
Interventions: DRUG: PD-1 Immune Checkpoint Inhibitor Combined With Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Different Exercise Modalities on Cardiovascular and Cognitive Response in Postmenopausal Women
Status: COMPLETED
Conditions: Menopause|Blood Pressure|Cognitive Decline
Interventions: OTHER: High intensity interval exercise session|OTHER: Isometric neuromuscular exercise session
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: NPI-0052 and Vorinostat in Patients With Non-small Cell Lung Cancer, Pancreatic Cancer, Melanoma or Lymphoma
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer|Pancreatic Cancer|Melanoma|Lymphoma|Multiple Myeloma
Interventions: DRUG: NPI-0052 (marizomib) + vorinostat
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Efficacy Study With QIVc in Pediatric Subjects
Status: COMPLETED
Conditions: Influenza, Human
Interventions: BIOLOGICAL: QIVc|BIOLOGICAL: Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Research Study Comparing RYBELSUS® to Other Blood Sugar Lowering Tablets in People Living in America With Type 2 Diabetes (REALYSE)
Status: ACTIVE_NOT_RECRUITING
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: semaglutide|DRUG: oral glucose-lowering medications (commercially available)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Levothyroxine in Pregnant SLE Patients
Status: WITHDRAWN
Conditions: Systemic Lupus Erythematosus
Interventions: DRUG: Levothyroxine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Oxytocin i.m./i.v. Versus Carbetocin i.v. in Elective Cesarean Sections
Status: COMPLETED
Conditions: Postpartum Hemorrhage
Interventions: DRUG: Oxytocin|DRUG: Carbetocin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Flumatinib Versus Imatinib Combined With Chemotherapy for de Novo Ph+ ALL
Status: RECRUITING
Conditions: Acute Leukemia
Interventions: DRUG: Flumatinib|DRUG: Imatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Salsalate to Treat Endothelial Dysfunction in HIV-infected Adults
Status: COMPLETED
Conditions: HIV|Endothelial Dysfunction|Inflammation|Insulin Resistance
Interventions: DRUG: Salsalate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pediatric and Caregiver Traumatic Stress Intervention (PACTS)
Status: NOT_YET_RECRUITING
Conditions: Traumatic Injury
Interventions: BEHAVIORAL: Caregiver Counseling for Childhood Traumatic Injury|BEHAVIORAL: Standard of Care for Childhood Traumatic Injury
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Curcumin Supplementation and Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Non Insulin Dependent Diabetes
Interventions: DIETARY_SUPPLEMENT: Curcumin|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Gabapentin on Post-Operative Pain in Minimally Invasive Sacrocolpopexy
Status: RECRUITING
Conditions: Post Operative Pain
Interventions: DRUG: Gabapentin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effectiveness of Musicotherapy in Weaning From Mechanical Ventilation
Status: UNKNOWN
Conditions: Weaning|Respiration, Artificial|Music Therapy
Interventions: PROCEDURE: music therapy intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Evaluate Diagnostic Performance and Safety of Pegsitacianine, an Intraoperative Fluorescence Imaging Agent for the Detection of Lung Malignancies in Patients Undergoing Routine Surgery
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DRUG: pegsitacianine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Nutritional and Functional Changes in Heart Failure and COPD
Status: COMPLETED
Conditions: Chronic Heart Failure|Chronic Obstructive Pulmonary Disorder
Interventions: DIETARY_SUPPLEMENT: BOOST High Protein
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Controlled Trial: 5-day Course of Telithromycin Versus Doxycycline for the Treatment of Mild to Moderate Scrub Typhus
Status: COMPLETED
Conditions: Scrub Typhus
Interventions: DRUG: Telithromycin|DRUG: Doxycycline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Trial of Magrolimab and Cetuximab with Pembrolizumab or Docetaxel for Recurrent/metastatic Head Neck Squamous Cell Carcinoma
Status: TERMINATED
Conditions: Head Neck|Squamous Cell Carcinoma of Head and Neck
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Ecallantide in Paediatric Patients With Acute Attacks of Hereditary Angioedema
Status: WITHDRAWN
Conditions: Hereditary Angioedema (HAE)
Interventions: BIOLOGICAL: ecallantide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Efficacy and Safety of BF-200 ALA Used With Photodynamic Therapy in Patients With Actinic Keratosis.
Status: COMPLETED
Conditions: Actinic Keratosis
Interventions: DRUG: Vehicle|DRUG: BF-200 ALA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fracture Pattern Following Bilateral Sagittal Split Osteotomy With or Without Impacted Third Molars
Status: NOT_YET_RECRUITING
Conditions: Impacted Third Molar Tooth|Osteotomy|Orthognathic Surgery|Mandibular Fractures
Interventions: PROCEDURE: Interoperative wisdom tooth removal in conjunction with BSSO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of DC-CIK to Treat Hepatocellular Carcinoma
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma (HCC)
Interventions: BIOLOGICAL: Dendritic and Cytokine-induced Killer Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: the Pharmacokinetic Profiles of Linagliptin With DW1029M
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Linagliptin 5mg|DRUG: DW1029M 1200mg and Linagliptin 5mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Real World Effectiveness and Safety of Hysteroscopic (Essure®) Compared to Laparoscopic Sterilization
Status: COMPLETED
Conditions: Sterility, Female|Contraception|Contraceptive Device; Complications
Interventions: DEVICE: Essure|PROCEDURE: Laparoscopic sterilization|DEVICE: Intrauterine Device (IUD)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Dose-finding Study of ASP2151 in Subjects With Herpes Zoster
Status: COMPLETED
Conditions: Herpes Zoster
Interventions: DRUG: ASP2151|DRUG: Valacyclovir hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: EBL Versus EBL and Propranolol for the Prevention of Variceal Rebleeding in Pts With Previous Variceal Treatment
Status: UNKNOWN
Conditions: Cirrhosis|Variceal Bleeding
Interventions: PROCEDURE: endoscopic band ligation|PROCEDURE: endoscopic band ligation+Propranolol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Randomised Controlled Trial of Hysteroscopic Resection of Mild Septum/Arcuate Uteri.
Status: UNKNOWN
Conditions: Arcuate Uterus
Interventions: PROCEDURE: hysteroscopic treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Topical Omega-3 Fatty Acids (REMOGEN® OMEGA) in the Treatment of Dry Eye
Status: COMPLETED
Conditions: Dry Eye Syndromes
Interventions: DEVICE: REMOGEN OMEGA|DEVICE: Povidone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Antibiotic Prophylaxis for Revision, Clean Head and Neck Surgery
Status: COMPLETED
Conditions: Surgical Wound Infection
Interventions: DRUG: Cefazolin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Epley Maneuver Versus Cawthorne-Cooksey Exercises in the Treatment of Benign Paroxysmal Positional Vertigo (BPPV)
Status: COMPLETED
Conditions: Benign Paroxysmal Positional Vertigo
Interventions: PROCEDURE: Epley maneuver
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Novel Closed-loop Propofol and Remifentanil System Guided by Bispectral Index Compared to a TCI Open-loop System
Status: COMPLETED
Conditions: Anesthesia, General|Anesthesia, Intravenous
Interventions: DEVICE: Closed-Loop propofol and remifentanil system by Bispectral Index|DEVICE: Open-Loop propofol and remifentanil by Target Controlled Infusion|DRUG: propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of CX-4945 in Combination With Gemcitabine and Cisplatin for Frontline Treatment of Cholangiocarcinoma
Status: COMPLETED
Conditions: Cholangiocarcinoma
Interventions: DRUG: CX-4945|DRUG: Cisplatin|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial to Evaluate the Effects of Food on the Bioavailability of CKD-397 in Healthy Male Subjects
Status: COMPLETED
Conditions: Benign Prostatic Hypertrophy (BPH)
Interventions: DRUG: CKD-397
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy and Locoregional Therapy Trial (Surgery or Radiation) for Patients With Head and Neck Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: HPV-Related Squamous Cell Carcinoma|HNSCC
Interventions: DRUG: nab-paclitaxel|DRUG: Carboplatin|DRUG: Nivolumab|DRUG: Cisplatin|DRUG: Hydroxyurea|DRUG: 5-FU|DRUG: Dexamethasone|DRUG: Famotidine|DRUG: Diphenhydramine|DRUG: Paclitaxel|PROCEDURE: Transoral robotic surgery (TORS)|RADIATION: Adjuvant RT|RADIATION: Chemoradiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevention of Post-partum Haemorrhage
Status: COMPLETED
Conditions: Postpartum Haemorrhage|Immediate Postpartum Hemorrhage
Interventions: PROCEDURE: controlled cord traction|PROCEDURE: Clinical signs of placental separation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Dapagliflozin Effect on Symptoms and Biomarkers in Patients With Heart Failure
Status: COMPLETED
Conditions: Chronic Heart Failure With Reduced Systolic Function
Interventions: DRUG: Dapagliflozin|DRUG: Dapagliflozin matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Biomarkers Predicting Acute Myocardial Infraction in Patients Without Standard Modifiable Risk Factors
Status: RECRUITING
Conditions: Cardiovascular Diseases|Acute Myocardial Infarction|Acute Coronary Syndrome|Metabolic Disturbance
Interventions: DIAGNOSTIC_TEST: Investigation of clinical, laboratory and imaging profile
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Outcomes of a Higher vs. Lower Hemodialysate Magnesium Concentration (Dial-Mag Canada)
Status: ACTIVE_NOT_RECRUITING
Conditions: Kidney Diseases|End-Stage Kidney Disease|Hemodialysis
Interventions: OTHER: Dialysate magnesium formulation of 1.5 mEq/L (0.75 mmol/L).|OTHER: Dialysate magnesium formulation of ≤1.0 mEq/L (≤0.5 mmol/L).
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Antioxidant Food Supplement on Sperm Proteomic Structure and Semen Parameters
Status: RECRUITING
Conditions: Asthenozoospermia
Interventions: BIOLOGICAL: Proxeed Plus 2*1 A arm|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Single-dose Study to Investigate the Pharmacokinetics of Intravenous FEP-TAZ in Patients With Renal Impairment
Status: COMPLETED
Conditions: Renal Impairment
Interventions: DRUG: Cefepime and Tazobactam combination
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: A Randomized, Double-Blind, Placebo-Controlled Study to Evaluate STS101 in the Acute Treatment of Migraine
Status: COMPLETED
Conditions: Migraine|Migraine With Aura|Migraine Without Aura
Interventions: DRUG: Dihydroergotamine|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Th Tl Xb Prescription on Reprogramming of Lipid Metabolism and Endothelial Injury for Cerebral Infarction Patients
Status: NOT_YET_RECRUITING
Conditions: Cerebral Infarction|Chinese Herbal Medicine|Clinical Trial|Lipid Metabolism Disorder|Endothelial Injury
Interventions: OTHER: Taohong Tongluo Xiaoban Prescription|OTHER: Fundamental medical treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Involving Field Radiotherapy in the Oligo-lesions(Metastasis/Recurrent/Refractory) of Ovarian Cancer
Status: UNKNOWN
Conditions: Ovarian Cancer|Neoplasm, Ovarian|Ovarian Neoplasm|Ovary Neoplasms|Neoplasm, Ovary|Neoplasms, Ovary|Ovary Neoplasm|Neoplasms, Ovarian|Ovary Cancer|Cancer, Ovarian Stromal|Cancers, Ovary|Ovary Cancers|Cancer, Ovarian|Cancers, Ovarian|Ovarian Cancers|Cancer of Ovary|Cancer of the Ovary
Interventions: DRUG: chemotherapy, targeted therapeutics, immunotherapy|RADIATION: IFRT, IMRT or SBRT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety of Intranasal Fentanyl (PecFent®) in the Treatment of Procedural Pain in the Elderly
Status: COMPLETED
Conditions: Pain Due to Certain Specified Procedures
Interventions: DRUG: intranasal fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Knot Burial Technique for Rectus Sheath Closure
Status: COMPLETED
Conditions: Cesarean Section Complications
Interventions: PROCEDURE: knot burial technique|PROCEDURE: classical closure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Treatment of SFA Lesions With 480 Biomedical STANZA™ Drug-Eluting Resorbable Scaffold (DRS) System
Status: COMPLETED
Conditions: Peripheral Arterial Disease|Intermittent Claudication|Vascular Diseases|Cardiovascular Diseases
Interventions: DEVICE: STANZA Drug-eluting resorbable Scaffold
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Electro-Neuro-Muscular Stimulation in ICU
Status: COMPLETED
Conditions: Myopathy|Neuropathy
Interventions: OTHER: Patients will receive daily sessions of electro-neuro-stimulation in the quadriceps muscle for 10 days
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Reverse Triple Negative Immune Resistant Breast Cancer
Status: UNKNOWN
Conditions: Triple-negative Breast Cancer
Interventions: DRUG: Choline|DRUG: anti-PD-1 antibody and chemotherapy|DRUG: Sodium Cromoglicate|DRUG: Efavirenz
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: DCS Versus DES for One-month DAPT in Patients With ACS: ONE-PASS Trial
Status: RECRUITING
Conditions: Acute Coronary Syndrome
Interventions: DEVICE: Drug-coated stent|DEVICE: Drug-eluting stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pragmatic Clinical Trial for a More Effective Concise and Less Toxic MDR-TB Treatment Regimen(s)
Status: COMPLETED
Conditions: Tuberculosis, Multidrug-Resistant|Extensively Drug-Resistant Tuberculosis|Tuberculosis, Pulmonary
Interventions: DRUG: Bedaquiline|DRUG: Pretomanid|DRUG: Moxifloxacin|DRUG: Linezolid|DRUG: Clofazimine|DRUG: Locally accepted standard of care which is consistent with the WHO recommendations for the treatment of M/XDR-TB.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of Sit Muscle Strength Training and Game on Elderly
Status: COMPLETED
Conditions: Aging|Physical Disability|Dementia|Elderly
Interventions: OTHER: Sit muscle strength training|OTHER: Game training|OTHER: Sitting strength + game training|OTHER: Health education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Study of 0444 Gel in the Treatment of Inflammatory Lesions of Rosacea
Status: COMPLETED
Conditions: Inflammatory Rosacea
Interventions: DRUG: 0444
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Positive Psychotherapy Based Psychoeducation on Pain Perception With Fibromyalgia Syndrome
Status: COMPLETED
Conditions: Fibromyalgia Syndrome
Interventions: BEHAVIORAL: The group will include patients with fibromyalgia syndrome who will receive positive psychotherapy.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Cognitive and Cerebral Blood Flow Effects of 2-week Caffeine Abstinence or Maintenance
Status: COMPLETED
Conditions: Cognitive Function|Mood|Cerebral Haemodynamics|Caffeine Withdrawal
Interventions: DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: Caffeine and Placebo|DIETARY_SUPPLEMENT: Placebo and Caffeine|DIETARY_SUPPLEMENT: Caffeine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Single Oral Dose Study Of PF-06409577 In Healthy Adult Subjects
Status: TERMINATED
Conditions: Healthy
Interventions: DRUG: PF-06409577 or Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Drug Screening Using Novel IMD in ACC and Salivary Cancers
Status: NOT_YET_RECRUITING
Conditions: Adenoid Cystic Carcinoma|Adenoid Cystic Carcinoma of the Salivary Gland
Interventions: COMBINATION_PRODUCT: Implantable Microdevice (IMD)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Intravenous Vitamin C on Intrapartum Maternal Fever After Epidural Labor Analgesia
Status: RECRUITING
Conditions: Obstetric Labor Complications|Fever
Interventions: DRUG: Vitamin C Injection|OTHER: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: First-line Gemcitabine/Cisplatin +/- Avelumab in Locally Advanced or Metastatic Bladder Carcinoma
Status: TERMINATED
Conditions: Bladder Carcinoma
Interventions: DRUG: Avelumab|DRUG: GC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Morphine and/or Nalbuphine as Adjuvants in Ultrasound Guided Interscalene Block: for Shoulder Surgeries
Status: UNKNOWN
Conditions: Rotator Cuff Tear
Interventions: DRUG: Morphine|DRUG: Nalbuphine|DRUG: Bupivacaine 0.5%|DRUG: Lidocaine Hydrochloride 1% and epinephrine 1:400,000
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Cognitive Behavioral Intervention to Reduce Procedural Anxiety Among Woman With High Risk Pregnancies With Scheduled Cesarean Deliveries
Status: RECRUITING
Conditions: Procedural Anxiety|High Risk Pregnancy|Fetal Complications
Interventions: BEHAVIORAL: Exposure Intervention|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Mozart Music on Cerebral Oxygenation and Behavioural Response of Premature Infants
Status: COMPLETED
Conditions: Premature Brain Oxygenation
Interventions: OTHER: Mozart music lullaby
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Rate of Torque Development and Voluntary Quadriceps Activation in Patients With Knee Osteoarthritis: A Quantitative Analysis Before and After a Single Session of Manual Physical Therapy
Status: UNKNOWN
Conditions: Knee Osteoarthritis|Knee Arthritis|Knee Pain Chronic|Knee Deformity|Knee Pain Swelling|Muscle Weakness|Muscle Weakness Condition|Power
Interventions: PROCEDURE: Manual Physical Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Erector Spinae Plane Block Versus Intercostal for VATS
Status: COMPLETED
Conditions: Lung Cancer|Lung Diseases
Interventions: PROCEDURE: ESP block|PROCEDURE: Intercostal block|PROCEDURE: Sham ESP block|PROCEDURE: Sham Intercostal block|DRUG: Bupivacaine-epinephrine|DRUG: Dexamethasone injection|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Do It Yourself (DIY) Coffee Study; Test Effect of Coffee on Cognition in an at Home Setting
Status: COMPLETED
Conditions: At Home Setting|Coffee With or Without Caffeine
Interventions: DIETARY_SUPPLEMENT: Coffee consumption
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of AK112 in Advanced Malignant Tumors
Status: RECRUITING
Conditions: Advanced Malignant Tumors
Interventions: DRUG: AK112|DRUG: AK117|DRUG: Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimization of the Diagnosis of Bone Fractures in Patients Treated in the Emergency Department by Using Artificial Intelligence for Reading Radiological Images in Comparison With Traditional Reading by the Emergency Doctor.
Status: RECRUITING
Conditions: Artificial Intelligence|Bone Fracture
Interventions: DEVICE: Artificial intelligence|PROCEDURE: Emergency physician
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Docetaxel and Vinorelbine Plus Sargramostim in Metastatic Malignant Melanoma
Status: COMPLETED
Conditions: Metastatic Melanoma
Interventions: DRUG: Vinorelbine|DRUG: Docetaxel|DRUG: Sargramostim
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Apatinib in the Treatment of Recurrence or Metastasis of Esophageal Cancer
Status: UNKNOWN
Conditions: Esophageal Squamous Cell Carcinoma|Apatinib|Recurrence|Metastasis
Interventions: DRUG: apatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Recurrence Rate of Mini-SLET vs. Limbal-Conjunctival Autograft in Primary Pterygium Excision
Status: COMPLETED
Conditions: Pterygium of Conjunctiva and Cornea
Interventions: PROCEDURE: Pterygium Excision
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of AL102 in Patients With Progressing Desmoid Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Desmoid|Desmoid Tumor
Interventions: DRUG: AL102|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Long-term Effects of COVID-19 Vaccines in Patients With Pulmonary Tumor
Status: WITHDRAWN
Conditions: Lung Cancer|Pulmonary Nodule, Solitary|Pulmonary Nodule, Multiple|COVID-19 Pneumonia|Vaccine Adverse Reaction|SARS-CoV-2 Acute Respiratory Disease
Interventions: BIOLOGICAL: Vaccine inoculation against SARS-CoV-2
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Investigate How JNJ-38518168 May Affect the Plasma Levels of Methotrexate in Rheumatoid Arthritis Participants
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: JNJ-38518168 / MTX
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioavailability and Safety Study Comparing Two Dose Levels of AMZ001 and One Dose Level of Diclofenac Sodium 1% Gel in Healthy Participants
Status: ACTIVE_NOT_RECRUITING
Conditions: Healthy
Interventions: DRUG: Diclofenac Sodium Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sero-epidemiological Survey of England in 2019/2020 - COVID-19
Status: UNKNOWN
Conditions: Serogroup C Meningococcal Meningitis|Diphtheria|COVID-19
Interventions: PROCEDURE: Venepuncture|PROCEDURE: Oral fluid swab
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Intradermal Suture Versus Stapling for Groin Skin Closure in Vascular Surgery (VASC-INF Trial)
Status: RECRUITING
Conditions: Surgical Site Infection
Interventions: PROCEDURE: Intradermal Suture|PROCEDURE: Metallic Staples
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Monitoring Highly Active Antiretroviral Therapy in HIV-infected Parents in Thailand
Status: COMPLETED
Conditions: HIV Infections
Interventions: PROCEDURE: Antiretroviral Drug Combination Switching Criteria|PROCEDURE: Antiretroviral Drug Combination Switching Criteria
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mixture of Prebiotics on Intestinal Microbiota of Patients Receiving Abdominal Radiotherapy.
Status: COMPLETED
Conditions: Prebiotics|Microbiota|Radiation Therapy Complication|Endometrial Neoplasms
Interventions: DIETARY_SUPPLEMENT: Inulin and Fructo-oligosaccharide|DIETARY_SUPPLEMENT: Maltodextrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Teaching the Social Determinants of Health to Nursing Students With Simulation
Status: COMPLETED
Conditions: Simulation of Physical Illness|Nurse's Role
Interventions: BEHAVIORAL: Standardized patient simulation|BEHAVIORAL: Manikin-based simulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Effect Of Vitalstim In Patients With Chronic Post-stroke Oropharyngeal Dysphagia
Status: COMPLETED
Conditions: Deglutition Disorders|Stroke
Interventions: BEHAVIORAL: standard clinical care|DEVICE: transcutaneous electrical stimulation at sensory level|DEVICE: transcutaneous electrical stimulation at motor level
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Investigation for Safety and Efficacy Study of CELT ACD (Arterial ClosureDevice)
Status: COMPLETED
Conditions: Cardiac Disease|Coronary Artery Disease
Interventions: DEVICE: CELT ACD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Evaluate the Pharmacokinetics and Safety Between HCP2201 and Co-administration of Each Component in Healty Male Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: HCP2201|DRUG: RLD2205|DRUG: RLD2206
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improving Efficacy of Voice Therapy Concepts Via Telepractice and Mobile App Technology
Status: RECRUITING
Conditions: Voice Disorders
Interventions: BEHAVIORAL: Conversation Training Therapy|BEHAVIORAL: Global Voice Prevention and Therapy Model|BEHAVIORAL: Modified Conversation Training Therapy|BEHAVIORAL: Modified Global Voice Prevention and Therapy Model
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION