pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Intravenous or Intra-abdominal Local Anesthetics for Postoperative Pain Management.
Status: COMPLETED
Conditions: Uterine Myoma|Persistent Post-menpausal Bleeding|Uterine Cancer
Interventions: DRUG: Normal saline|DRUG: Intravenous Lidocaine|DRUG: Intra-abdominal Lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Chinese Herbal Medicine Xiaojidaozhi Decoction in the Treatment of Childhood Constipation
Status: COMPLETED
Conditions: Constipation|Chinese Herbal Medicine
Interventions: DRUG: Xiaojidaozhi Decoction|DRUG: Placebo|DRUG: Fiberform|BEHAVIORAL: Toilet training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Trial to Evaluate the Safety and Tolerability of Repeated Intravitreal Injection of IBI302 in Neovascular AMD Patients
Status: COMPLETED
Conditions: Neovascular Age-related Macular Degeneration
Interventions: DRUG: IBI302 (the first dose level)|DRUG: IBI302 (the second dose level)|DRUG: Aflibercept
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Arformoterol Tartrate Inhalation Solution in Subjects With Chronic Obstructive Pulmonary Disease
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease|Bronchitis|Emphysema
Interventions: DRUG: Arformoterol tartrate inhalation solution|DRUG: Arformoterol 25 ųg BID|DRUG: Formoterol 12 ųg BID|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Activated CHARcoal in Poisoned Patient
Status: NOT_YET_RECRUITING
Conditions: Charcoal, Decontamination, Poisoning
Interventions: DRUG: Activated Charcoal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Swallowable Sponge Cell Sampling Device and Next Generation Sequencing in Detecting Esophageal Cancer in Patients With Low or High Grade Dysplasia, Barrett Esophagus, or Gastroesophageal Reflux Disease
Status: COMPLETED
Conditions: Barrett Esophagus|Dysplasia|Esophageal Adenocarcinoma|Esophageal Squamous Cell Carcinoma|Gastroesophageal Reflux Disease|Metaplasia
Interventions: OTHER: Cytology Specimen Collection Procedure|OTHER: Laboratory Biomarker Analysis|OTHER: Quality-of-Life Assessment|DEVICE: Swallowable Sponge Cell Sampling Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: A Pilot Study of Fenofibrate to Prevent Kidney Function Loss in Type 1 Diabetes
Status: RECRUITING
Conditions: Diabetic Nephropathies
Interventions: DRUG: Fenofibrate|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Beer or Ethanol Effects on the Response to High Intensity Interval Training: A Controlled Study in Healthy Individuals
Status: COMPLETED
Conditions: Drinking, Alcohol|Exercise
Interventions: OTHER: HIIT-AB Group|OTHER: HIIT-NAB Group|OTHER: HIIT-SW Group|OTHER: HIIT-ASW Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: TF (SENSIMED Triggerfish) in Intraocular Anti-VEGF (Vascular Endothelial Growth Factor) Injection
Status: TERMINATED
Conditions: Neovascular Age Related Macular Degeneration (AMD)|Open Angle Glaucoma
Interventions: PROCEDURE: Intraocular anti-VEGF injection|DEVICE: SENSIMED Triggerfish
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Low-frequency Transcranial Magnetic Stimulation To Enhance Motor Recovery In The Subacute Phase After Stroke
Status: COMPLETED
Conditions: Stroke
Interventions: OTHER: Repetitive transcranial magnetic stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Video Messaging About Diet, Exercise and Weight Gain in Pregnancy in Regional and National Samples
Status: COMPLETED
Conditions: Pregnancy|Weight Gain
Interventions: BEHAVIORAL: Responses to Brief Video Messages (Facebook)|BEHAVIORAL: Response to Brief Video Messages (Clinic)|BEHAVIORAL: Response to Brief Video Messages (Social Network)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pembrolizumab in Post Radical Operation ESCC Patients With Lymph Node Positive ( KEYSTONE-004 )
Status: UNKNOWN
Conditions: ESCC|Adjuvant Treatment|Lymph Node Positive|Pembrolizumab
Interventions: DRUG: Pembrolizumab Injection [Keytruda]
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of TQ-B3525 in the Treatment of Relapsed / Refractory Follicular Lymphoma (FL)
Status: UNKNOWN
Conditions: Relapsed / Refractory Follicular Lymphoma
Interventions: DRUG: TQ-B3525
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Zonisamide Capsules 100 mg of Dr.Reddy's Laboratories Limited Under Fed Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Zonisamide|DRUG: Zonegran
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Home-based Exercise and Physical Activity Intervention After Kidney Transplantation: Impact of Exercise Intensity
Status: RECRUITING
Conditions: Physical Activity|Exercise Training|Kidney Transplantation|Physical Fitness|Cardiovascular Health|Gut Microbiome|Health-related Quality of Life|Implementation|Cost-effectiveness
Interventions: BEHAVIORAL: Exercise/physical activity
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Palatability (Taste) of Oral Formulations of Bosutinib
Status: COMPLETED
Conditions: CML
Interventions: DRUG: 200 Mg capsules of bosutinib in Water solution|DRUG: bosunitib sorbitol|DRUG: Bosutinib Mannitol|DRUG: bosutinib in mannitol low sweet|DRUG: bosutinib in mannitol high sweet|DRUG: bosutinib taste low flavour|DRUG: bosutinib high flavour|DRUG: bosutinib capsules in applesauce|DRUG: Bosutinib capsules in yogurt|DRUG: bosutinib capsules in water|DRUG: Bosutinib capsules in low sweet|DRUG: bosutinib capsules high sweet|DRUG: bosutinib capsules low flavour|DRUG: bosutinib capsules high flavour
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: A Trial of a Botanical Drug Containing East Indian Sandalwood Oil (EISO) For Treatment of Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis|Eczema
Interventions: DRUG: SAN007 5% cream|DRUG: Placebo|DRUG: SAN007 10% cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I Study to Assess the Safety,Tolerability, PK, PD, and Food Effect of HSK39297 in Healthy Subjects
Status: RECRUITING
Conditions: Healthy
Interventions: DRUG: HSK39297
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Esophagectomy in Middle and Lower Thoracic Esophageal Cancer Patients Through Left Versus Right Transthoracic Approach
Status: UNKNOWN
Conditions: Esophageal Cancer
Interventions: PROCEDURE: Left thoracotomy|PROCEDURE: Right thoracotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of SPD465 in Adults With ADHD
Status: COMPLETED
Conditions: Attention Deficit Disorder With Hyperactivity
Interventions: DRUG: Neutral salts of dextroamphetamine sulfate, USP, amphetamine sulfate, USP, d-amphetamine saccharate, d, l-amphetamine aspartate monohydrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Single Dose Rectal Diclofenac With Oral Diclofenac for the Relief of Perineal Pain Within 24 Hours After Episiotomy
Status: COMPLETED
Conditions: Pain Relief After Episiotomy
Interventions: DRUG: Diclofenac
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ED-TREAT (Early Detection and Treatment to Reduce Events With Agitation Tool) Compared to Usual Care
Status: NOT_YET_RECRUITING
Conditions: Psychomotor Agitation|Behavioral Disorder
Interventions: OTHER: ED-TREAT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Nursing Assistant Intervention to Prevent Delirium in Nursing Homes
Status: COMPLETED
Conditions: Delirium
Interventions: OTHER: Delirium-prevention|OTHER: Sham comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of the Scleroderma Patient-centered Intervention Network COVID-19 Home-isolation Activities Together Program
Status: COMPLETED
Conditions: Scleroderma|Scleroderma, Systemic|Systemic Sclerosis
Interventions: OTHER: SPIN-CHAT Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: ABR-217620 in Combination With Docetaxel in Patients With Advanced Non-small Cell Lung Cancer
Status: COMPLETED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: ABR-217620|DRUG: docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial to Evaluate Para-aortic Lymphadenectomy for Gastric Cancer
Status: COMPLETED
Conditions: Gastric Neoplasm
Interventions: PROCEDURE: Surgery: D2 dissection|PROCEDURE: Surgery: D2+paraaortic dissection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nine Month Course of Anti-HIV Medications for People Recently Infected With HIV
Status: TERMINATED
Conditions: HIV Infections
Interventions: DRUG: Emtricitabine/ tenofovir disoproxil fumarate|DRUG: Lopinavir/Ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open-label Pharmacokinetic Study of Iron Isomaltoside 1000 (Monofer®) Administered by 500 mg IV Bolus Injection or 1000 mg Intravenous Infusion to Patients With Non-hematological Malignancies Associated With Chemotherapy Induced Anaemia (CIA)
Status: COMPLETED
Conditions: Non-hematological Malignancies
Interventions: DRUG: 500 mg iron isomaltoside 1000|DRUG: 1000 mg iron isomaltoside 1000
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of Insect Repellent and Insecticide Treated Nets in Lao PDR
Status: UNKNOWN
Conditions: Malaria|Dengue|Japanese Encephalitis
Interventions: DRUG: 20% deet insect repellent|DRUG: placebo control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Clinical Trial to Evaluate the Efficacy and Safety of DW1125 and DW1125A
Status: COMPLETED
Conditions: Hypercholesterolemia, Dyslipidemia
Interventions: DRUG: Ezetimibe/Atorvastatin 10/5 mg|DRUG: Atorvastatin 5mg|DRUG: Ezetimibe 10mg|DRUG: Atorvastatin 10mg|DRUG: DW1125 placebo|DRUG: DW1125A placebo|DRUG: DW1125E placebo|DRUG: DW1125A-1 placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Photomedicine Project 14: PBMT for Performance Enhancement in SOF
Status: NOT_YET_RECRUITING
Conditions: Photobiomodulation Therapy|Photomedicine|Low-Level Laser Therapy|Performance Enhancement|Quadriceps|Special Operations Readiness
Interventions: DEVICE: THOR3 training + Photobiomodulation Therapy (PBMT)|DEVICE: THOR3 training + sham PBMT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Using Preoperative Anxiety Score to Determine the Precise Dose of Butorphanol for Sedation
Status: COMPLETED
Conditions: Preoperative Anxiety|Precise Dose of Butorphanol
Interventions: DRUG: Butorphanol|OTHER: Physiological saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A United States Study of the Safety and Tolerability of Corlux for Psychotic Symptoms in Psychotic Major Depression
Status: COMPLETED
Conditions: Major Depressive Disorder|Psychotic Disorders
Interventions: DRUG: mifepristone|DRUG: mifepristone matched placebo|DRUG: mifepristone 600 mg|DRUG: mifepristone 1200 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Haploid Allogeneic Transplant Using the CliniMACS System
Status: TERMINATED
Conditions: Acute Myelogenous Leukemia (AML) - Relapsed, Primary Refractory Disease or Poor Risk Factors|Chronic Myelogenous Leukemia (CML) - Accelerated or Second Chronic Phase|Myelodysplastic Syndrome (MDS) - High and Intermediate Risk|Non-Hodgkin's Lymphoma (NHL)|Chronic Lymphocytic Leukemia (CLL) - Refractory
Interventions: DEVICE: CliniMACS System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: R0 Resection Rate Between CSP, cEMR and hEMR for 1-2 cm Colorectal SSLs
Status: RECRUITING
Conditions: Residual Disease
Interventions: PROCEDURE: Cold snaring polypectomy/ Cold EMR/Hot EMR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Flaxseed Lignan Supplementation in Elderly Participants With Stage I Hypertension
Status: COMPLETED
Conditions: Hypertension
Interventions: DIETARY_SUPPLEMENT: BeneFlax®|BEHAVIORAL: Walking training|BEHAVIORAL: Flexibility training|DIETARY_SUPPLEMENT: Placebo (Whey Protein)|BEHAVIORAL: Dash Eating Plan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intestinal Lavage to Promote Enteral Feeding and Prevent Necrotizing Enterocolitis in Extremely Preterm Infants
Status: RECRUITING
Conditions: Necrotizing Enterocolitis|Time to Full Enteral Nutrition
Interventions: OTHER: Intestinal lavage with normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of Frontline Dasatinib Plus Chemotherapy in Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia (PH+ALL)
Status: COMPLETED
Conditions: Philadelphia Positive Acute Lymphoblastic Leukemia
Interventions: DRUG: Dasatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of a Bupivacaine Patch (Eladur™) to Treat Post- Herpetic Neuralgia
Status: COMPLETED
Conditions: Postherpetic Neuralgia|Pain
Interventions: DRUG: Transdermal/Patch (Bupivacaine TTS [Eladur™])
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Doxorubicin With Cisplatin, High-Dose Methotrexate, and Additional Risk-Adapted Outpatient Chemotherapy
Status: TERMINATED
Conditions: Osteosarcoma
Interventions: DRUG: Doxorubicin|DRUG: Cisplatin|DRUG: Methotrexate|DRUG: Leucovorin|DRUG: Dexrazoxane|DRUG: Ifosfamide|BEHAVIORAL: Questionnaire|DRUG: Gemcitabine|DRUG: Sargramostim|PROCEDURE: Surgery|DRUG: Mesna
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Balanced Multi-Electrolyte Solution Versus Saline Trial for Diabetic KetoAcidosis
Status: NOT_YET_RECRUITING
Conditions: Diabetic Ketoacidosis
Interventions: DRUG: Plasma-Lyte 148|DRUG: 0.9% sodium chloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Patient's Experience With Physician Assistant Providers (PEPAP)
Status: UNKNOWN
Conditions: Joint Diseases, Midlevel Providers, Nurse Practitioners, Physician Assistants, Patient Perceptions, Patient Preferences
Interventions: OTHER: Biosketch Card
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Evaluation of 4 Artemisinin-based Combinations for Treating Uncomplicated Malaria in African Children
Status: COMPLETED
Conditions: Fever|Malaria
Interventions: DRUG: amodiaquine-artesunate (ASAQ)|DRUG: dihydroartemisinin-piperaquine (DHAPQ)|DRUG: artemether-lumefantrine (AL)|DRUG: Lapdap (Chlorproguanil-Dapsone) + artesunate (AS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fissure Caries Inhibition Study With Solea CO2-9.3μm Short-pulsed Laser
Status: COMPLETED
Conditions: Dental Caries
Interventions: DEVICE: Laser|OTHER: Fluoride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of MRA on Cardiovascular Disease in Patients With Hypertension and Hyperaldosteronemia
Status: ENROLLING_BY_INVITATION
Conditions: Hypertension|Hyperaldosteronaemia
Interventions: DRUG: Mineralocorticoid Receptor Antagonists(MRAs)|OTHER: Blank control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Impact of Different Restorative Treatments for Deep Caries Lesion in Primary Teeth
Status: COMPLETED
Conditions: Deep Caries Lesion of Primary Teeth
Interventions: OTHER: HVGIC|OTHER: Indirect pulp capping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of 24-hour Intraocular Pressure Fluctuation Recording With the SENSIMED Triggerfish Contact Lens Sensor
Status: COMPLETED
Conditions: Primary Open Angle Glaucoma|Healthy Subjects
Interventions: DEVICE: SENSIMED Triggerfish
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Rosuvastatin in Preventing Myonecrosis in Elective Percutaneous Coronary Interventions (PCIs)
Status: COMPLETED
Conditions: Periprocedural Myocardial Necrosis
Interventions: DRUG: ROSUVASTATIN
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antibody Seroprevalence and Rate of Asymptomatic Infections With SARS-CoV-2 in Austrian Hospital Personnel.
Status: COMPLETED
Conditions: Severe Acute Respiratory Syndrome Coronavirus 2|SARS-CoV 2|Coronavirus Infection|Covid19
Interventions: DIAGNOSTIC_TEST: a specifically designed self-administered questionnaire
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Combination Chemotherapy and Rituximab With Pegfilgrastim Followed by Rituximab, in Large B-Cell Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Non-Hodgkins Lymphoma
Interventions: DRUG: Cyclophosphamide|DRUG: Mitoxantrone|DRUG: Vincristine|DRUG: Prednisone|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Feasibility Study to Evaluate the AccuraSee in Correcting Residual Refractive Errors After Cataract Surgery
Status: COMPLETED
Conditions: Refractive Errors
Interventions: DEVICE: AccuraSee IOPCL with +3.0D add
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Canola Oil Multi-center Intervention Trial II
Status: COMPLETED
Conditions: Cardiovascular Disease|Metabolic Syndrome
Interventions: OTHER: Canola Oil|OTHER: High oleic acid canola oil|OTHER: Western diet oil combination
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Vaginal Preparation and Azithromycin to Reduce Post Cesarean Infections
Status: TERMINATED
Conditions: Infection|Obstetric Labor Complications|Endometritis|Cesarean Delivery Affecting Fetus|Wounds Injuries
Interventions: PROCEDURE: Vaginal Preparation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effects of Individualized PEEP Guided by Driving Pressure on Postoperative Atelectasis in Patients With Morbid Obesity
Status: RECRUITING
Conditions: Pulmonary Atelectasis|Obesity, Morbid
Interventions: PROCEDURE: Individualized PEEP group|PROCEDURE: Fixed PEEP group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nasal Humidified High Flow Oxygen During Weaning From Mechanical Ventilation : Ultrasonography Study
Status: COMPLETED
Conditions: Adult Patients Ventilated More Than 48 h|Stable Respiratory and Hemodynamic Conditions for SBT|Consent of Patients|Arterial Line
Interventions: OTHER: mechanical ventilation|OTHER: mechanical ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aerobic Training for Management of Post-Concussion Syndrome in Adolescents
Status: COMPLETED
Conditions: Concussion|Post-concussion Syndrome|Sports Injury
Interventions: BEHAVIORAL: Aerobic Training Intervention|BEHAVIORAL: Stretching Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transdiagnostic Treatment Personalization
Status: COMPLETED
Conditions: Anxiety Disorders|Depressive Disorder|Post Traumatic Stress Disorder|Obsessive-Compulsive Disorder
Interventions: BEHAVIORAL: Standard UP Treatment|BEHAVIORAL: Capitalization UP Treatment|BEHAVIORAL: Compensation UP Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Safety of Beta-blockers Drugs in Adults With Spinal Hemangioma
Status: UNKNOWN
Conditions: Spinal Tumor|Spinal Hemangioma|Beta Blocker Toxicity
Interventions: DRUG: Atenolol Pill|DRUG: Propranolol Pill
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Dynamics of Verbal and Non-verbal Interaction in Healthy Subjects, Through the Recording of Body Movements and Non-invasive Neurophysiological Techniques
Status: RECRUITING
Conditions: Neuroscience|Neuromodulation
Interventions: BEHAVIORAL: behavioral 1|BEHAVIORAL: behavioral 2|DEVICE: neuromodulation 1|DEVICE: neuromodulation 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SCREENING
Clinical trial: Efficacity and Safety of Mechanical Insufflation-exsufflation on ICU
Status: UNKNOWN
Conditions: Mucus Retention|Mechanical Ventilation Complication|Mucus; Plug, Tracheobronchial
Interventions: OTHER: Chest physiotherapy techniques|DEVICE: Mechanical insufflation-exsufflation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Ascending Dose Study of the Safety and Tolerability of REGN6490 in Healthy Volunteers
Status: TERMINATED
Conditions: Healthy Volunteer
Interventions: DRUG: REGN6490|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combined Exercise and Cognitive Stimulation for Falls Prevention
Status: UNKNOWN
Conditions: Fall|Frailty|Cognition Disorders in Old Age|Exercise|Cognitive Change
Interventions: OTHER: Vivfrail-Cog combined multicomponent physical exercise and cognitive stimulation.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of 400 mg Efavirenz Versus Standard 600 mg Dose in HIV/TB Co-infected Patients
Status: UNKNOWN
Conditions: HIV Infections|Tuberculosis
Interventions: DRUG: Efavirenz 600mg|DRUG: Efavirenz 400mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intrauterine Infusion of GCSF and Reproductive Outcomes in Infertile Women With History of RIF
Status: RECRUITING
Conditions: Recurrent Implantation Failure|Granulocyte Colony-Stimulating Factor|Infertility
Interventions: DRUG: Granulocyte Colony-Stimulating Factor|OTHER: placebo
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Immunization Anti HLA in the Liver Transplant Recipients (DSATH)
Status: UNKNOWN
Conditions: Liver Transplantation|Graft Failure
Interventions: BIOLOGICAL: Donor specific antibodies|BIOLOGICAL: Serum bank|BIOLOGICAL: DNA bank|PROCEDURE: Liver biopsy|PROCEDURE: Liver ultrasounds and Fibroscan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Added Value of Quantification of Lung Function in Patients Undergoing Radiotherapy, Using Tc-99m-MAA SPECT-CT
Status: UNKNOWN
Conditions: Lung Cancer
Interventions: RADIATION: pulmonary perfusion/reserve with Tc-99m-MAA SPECT/ Low dose CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation of FB-401 in Children, Adolescents and Adults (2 Years and Older) With Mild to Moderate Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: BIOLOGICAL: FB-401|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ultrasound to Guide Treatment Decisions in Patients With Rheumatoid Arthritis According to a T2T Approach
Status: RECRUITING
Conditions: Arthritis, Rheumatoid|Ultrasound|Treat to Target
Interventions: DIAGNOSTIC_TEST: Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pentoxyphilline Versus Fecal Microbiota Therapy in Severe Alcoholic Hepatitis
Status: COMPLETED
Conditions: Alcoholic Hepatitis
Interventions: DRUG: Pentoxiphylline|DRUG: Stool microbiota transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: hCT-MSC in Children With Autism Spectrum Disorder
Status: COMPLETED
Conditions: Autism|Autism Spectrum Disorder
Interventions: BIOLOGICAL: Cord Tissue Mesenchymal Stromal Cells|OTHER: Placebo Infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Strongest Families (Formerly Family Help Program): Pediatric Disruptive Behaviour Disorder
Status: COMPLETED
Conditions: Pediatric Disruptive Behaviour Disorder
Interventions: BEHAVIORAL: Strongest Families (formerly Family Help Program): Behaviour Disorder Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Spider Phobia Opposite Action Treatment Study
Status: TERMINATED
Conditions: Specific Phobia
Interventions: BEHAVIORAL: Biofeedback Relaxation Training|BEHAVIORAL: Exposure Therapy|BEHAVIORAL: Exposure with Threat-Relevant Opposite Actions|BEHAVIORAL: Exposure with Threat-Irrelevant Opposite Actions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity Study of Inactivated Nasal Influenza Vaccine NB-1008 Administered by Sprayer
Status: COMPLETED
Conditions: Healthy Adult Volunteers
Interventions: BIOLOGICAL: NB-1008|BIOLOGICAL: Fluzone IN
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Effectiveness of Proprietary Rehabilitation Program in Patients After COVID-19 Infection
Status: RECRUITING
Conditions: COVID-19|Rehabilitation
Interventions: OTHER: Respiratory training with the use of resistance set on respiratory muscle trainer|OTHER: Respiratory training without resistance set on respiratory muscle trainer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Nasal Inhalation of Pulmozyme in Patients With Cystic Fibrosis and Chronic Rhinosinusitis
Status: COMPLETED
Conditions: Cystic Fibrosis|Rhinosinusitis
Interventions: DRUG: Dornase alfa (Pulmozyme)|DRUG: isotonic saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Arterial Catheter to Monitor Glycemia
Status: UNKNOWN
Conditions: Critical Illness|Hyperglycemia
Interventions: PROCEDURE: Manual and automated washing of the peripherical lines|PROCEDURE: Automated washing of the peripherical lines
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of Implant Coating (BoneMaster) on Migration and Clinical Outcome in Hip Arthroplasty With the Exceed Cup
Status: ACTIVE_NOT_RECRUITING
Conditions: Osteoarthritis
Interventions: DEVICE: Prosthesis, BoneMaster-Exceed cup (Biomet)|DEVICE: Prosthesis Exceed cup without HA (Biomet)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of WB-EMS on Parkinson's Disease
Status: ENROLLING_BY_INVITATION
Conditions: Parkinson Disease
Interventions: OTHER: Strenght training combined with WB-EMS|OTHER: Cardiovascular training with WB-EMS|OTHER: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tamoxifen Following Combination Chemotherapy in Treating Women With Operable Invasive Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: CMF regimen|DRUG: cyclophosphamide|DRUG: fluorouracil|DRUG: methotrexate|DRUG: tamoxifen citrate|PROCEDURE: conventional surgery|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Hsv 1 and 2 Gowey Protocol Versus Placebo
Status: COMPLETED
Conditions: Herpes
Interventions: OTHER: Versabase gel with sarracenia purpurea 20% liquid extract|OTHER: placebo (versabase gel only)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety & Efficacy of Low Dose Aspirin / Ivermectin Combination Therapy for Treatment of Covid-19 Patients
Status: UNKNOWN
Conditions: Covid19
Interventions: DRUG: 3-dayIVM 200 mcg/kg/day/14-day 75mgASA/day + standard of care (intervention 1)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Michigan Split-belt Treadmill Training Program to Improve Acute Knee Biomechanics After ACL Reconstruction
Status: NOT_YET_RECRUITING
Conditions: ACL|ACL Injury
Interventions: BEHAVIORAL: Split-belt Training|BEHAVIORAL: Tied-Belt Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Caspofungin Versus Fluconazole in Preventing Invasive Fungal Infections (IFI) in Patients Undergoing Chemotherapy for Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Acute Myeloid Leukemia|Adult Acute Monoblastic Leukemia|Adult Acute Monocytic Leukemia|Adult Acute Myeloid Leukemia in Remission|Adult Acute Myeloid Leukemia With Inv(16)(p13.1q22); CBFB-MYH11|Adult Acute Myeloid Leukemia With Maturation|Adult Acute Myeloid Leukemia With Minimal Differentiation|Adult Acute Myeloid Leukemia With t(16;16)(p13.1;q22); CBFB-MYH11|Adult Acute Myeloid Leukemia With t(8;21); (q22; q22.1); RUNX1-RUNX1T1|Adult Acute Myeloid Leukemia With t(9;11)(p22.3;q23.3); MLLT3-KMT2A|Adult Acute Myeloid Leukemia Without Maturation|Adult Acute Myelomonocytic Leukemia|Alkylating Agent-Related Acute Myeloid Leukemia|Childhood Acute Monoblastic Leukemia|Childhood Acute Monocytic Leukemia|Childhood Acute Myeloid Leukemia in Remission|Childhood Acute Myeloid Leukemia With Maturation|Childhood Acute Myeloid Leukemia With Minimal Differentiation|Childhood Acute Myeloid Leukemia Without Maturation|Childhood Acute Myelomonocytic Leukemia|Fungal Infection|Myeloid Neoplasm|Neutropenia|Recurrent Adult Acute Myeloid Leukemia|Recurrent Childhood Acute Myeloid Leukemia|Secondary Acute Myeloid Leukemia|Untreated Adult Acute Myeloid Leukemia|Untreated Childhood Myeloid Neoplasm
Interventions: DRUG: Caspofungin Acetate|DRUG: Fluconazole|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Immunogenicity and Safety of a DTPa-HBV-IPV/Hib Vaccine Given at 2, 3 and 4 Months of Age
Status: COMPLETED
Conditions: Acellular Pertussis|Tetanus|Diphtheria|Hepatitis B|Poliomyelitis|Haemophilus Influenzae Type b
Interventions: BIOLOGICAL: Infanrix hexa Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Pilot Randomized Study of RD-X19 Tx Device in Subjects With PCC (Long Covid) in the Outpatient Setting
Status: TERMINATED
Conditions: Post COVID-19 Condition (PCC)
Interventions: DEVICE: RDX-19
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment Strategy to Prevent Mood Disorders Following Traumatic Brain Injury
Status: COMPLETED
Conditions: Traumatic Brain Injury
Interventions: DRUG: Placebo|DRUG: Sertraline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Early FES Cycling in Acute Spinal Cord Injury for Neuromuscular Preservation and Neurorecovery
Status: COMPLETED
Conditions: Acute Spinal Cord Injury
Interventions: DEVICE: Early FES|DEVICE: Delayed FES
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Effects of Mobilization With Movement and Kinesiotaping in Patellofemoral Pain Syndrome
Status: COMPLETED
Conditions: Patellofemoral Pain Syndrome
Interventions: OTHER: Mulligan's Straight leg-raise with traction|OTHER: Mulligan's Mobilization with Movement|OTHER: Kinesiotaping|OTHER: Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: BCI and FES for Hand Therapy in Spinal Cord Injury
Status: COMPLETED
Conditions: Spinal Cord Injury
Interventions: DEVICE: BCI-FES|DEVICE: Passive muscle stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of a Probiotic on Aspects of Mental Wellness
Status: COMPLETED
Conditions: Mental Health Wellness
Interventions: DIETARY_SUPPLEMENT: Dietary Supplement: Probiotics|DIETARY_SUPPLEMENT: Dietary Supplement: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Family-based Lifestyle Intervention Program and Carotenoid Supplementation for Children With Obesity
Status: COMPLETED
Conditions: Pediatric Obesity
Interventions: OTHER: Lifestyle intervention and carotenoid supplements|OTHER: Lifestyle intervention and placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: COugh Among Hypertensive Patients Treated With Telmisartan, Who Had to Stop previoUs ACE-i Treatment Due to couGH in Slovakia
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Telmisartan (Kinzal/Pritor, BAY68-9291)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study on the Therapeutic Effect and Mechanism of Transcranial Plasma Stimulation in the Treatment of Chronic Insomnia
Status: RECRUITING
Conditions: Chronic Insomnia Disorder
Interventions: DEVICE: Plasma therapy equipment|DEVICE: Fake therapeutic device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: TAP-Block in Abdominal Aortic Surgery
Status: COMPLETED
Conditions: Aortic Aneurysm, Abdominal
Interventions: DRUG: Ropivacaine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Relationship Between Dyslipidemia and The Response of Diabetic Macular Edema to Intravitreal Injection of Anti Vascular Endothelial Growth Factor Agents
Status: RECRUITING
Conditions: Diabetic Macular Edema
Interventions: DRUG: Ranibizumab Injection [Lucentis]|DRUG: Aflibercept Injection [Eylea]
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Alzheimer's Disease: Potential Benefit of Isoflavones
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: Novasoy|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate Efficacy and Safety of Cobimetinib Plus Atezolizumab and Atezolizumab Monotherapy Versus Regorafenib in Participants With Metastatic Colorectal Adenocarcinoma (COTEZO IMblaze370)
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: Atezolizumab (MPDL3280A), an Engineered Anti-PDL1 Antibody|DRUG: Cobimetinib|DRUG: Regorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A New Strategy Regarding Discontinuation of Dual Antiplatelet
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DEVICE: Zotarolimus-eluting stent|DEVICE: Zotarolimus-eluting stent for ACS and DM|DEVICE: Everolimus-eluting stent for long lesion|DEVICE: Sirolimus-eluting stent for short lesion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Esketamine Induction Intubation in ICU Patients.
Status: UNKNOWN
Conditions: Critically Ill Patients
Interventions: DRUG: Esketamine Hydrochloride 28 Mg in 0.2 mL NASAL SOLUTION [Spravato]|DRUG: midazolam, fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Varying Testosterone Levels on Insulin Sensitivity in Men With Idiopathic Hypogonadotropic Hypogonadism (IHH)
Status: TERMINATED
Conditions: Hypogonadotropic Hypogonadism|Kallmann Syndrome
Interventions: DRUG: Anastrozole Pill|DRUG: Testosterone|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Timing of Stoma Closure in Neonates
Status: COMPLETED
Conditions: Enterocolitis, Necrotizing|Atresia; Bowel|Gastroschisis|Meconium Ileus|Premature Birth|Bowel Obstruction|Perforation Bowel
Interventions: OTHER: No intervention - observational study
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: MENOPUR® in a Gonadotropin-Releasing Hormone (GnRH) Antagonist Cycle With Single-Blastocyst Transfer in a High Responder Subject Population
Status: COMPLETED
Conditions: Infertility
Interventions: DRUG: menotropin|DRUG: recombinant FSH
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: XLCART001 Treatment in Relapsed/Refractory/High-risk B-cell Malignancy Subjects
Status: UNKNOWN
Conditions: Lymphoma, B-Cell|Leukemia, B-cell
Interventions: BIOLOGICAL: chimeric antigen receptor T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pulsed Radiofrequency Therapy for Hand OsteoArthritis Pain
Status: RECRUITING
Conditions: Hand Osteoarthritis
Interventions: DEVICE: Transcutaneous pulsed radiofrequency|DEVICE: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic and Pharmacodynamic Assessment of a Novel, Pharmaceutical Lipid-Aspirin Complex
Status: COMPLETED
Conditions: Bioequivalence
Interventions: DRUG: Aspirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Recruitment and Behavioral Economic Strategies
Status: ENROLLING_BY_INVITATION
Conditions: Surgery|Adolescent Behavior
Interventions: BEHAVIORAL: Behavioral Economics (BE) recruitment strategies|OTHER: Biofeedback-based virtual reality (VR-BF)|OTHER: Manage My Pain
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Randomized Controlled Trial of Inhaled Amphotericin B for Maintaining Remission in Allergic Bronchopulmonary Aspergillosis
Status: COMPLETED
Conditions: Allergic Bronchopulmonary Aspergillosis
Interventions: DRUG: Inhaled budesonide|DRUG: Inhaled amphotericin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EMPoWER Study - Strengths-based Behavioral Intervention for Youth With Type 1 Diabetes
Status: RECRUITING
Conditions: Type 1 Diabetes
Interventions: BEHAVIORAL: Teen Videos|BEHAVIORAL: Type 1 Doing Well (T1DW) Program|BEHAVIORAL: Diabetes Care Provider Intervention Delivery|OTHER: Diabetes-Related Information and Resources Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Nerve Blocks vs Local Injections for Post-op Pain Prevention in Laparoscopic Cholecystectomy in Children
Status: COMPLETED
Conditions: Laparoscopic Cholecystectomy
Interventions: PROCEDURE: TAP Blocks|PROCEDURE: local wound infiltration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Increasing Ureagenesis in Inborn Errors of Metabolism With N-Carbamylglutamate
Status: WITHDRAWN
Conditions: Urea Cycle Disorders, Inborn|Inborn Errors of Metabolism|Propionic Acidemia|Methylmalonic Acidemia|Carbamyl Phosphate Synthetase Deficiency
Interventions: DRUG: N-carbamylglutamate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Nationwide Phase 2 Trial of Patients With Smoldering and Active Multiple Myeloma (MM)
Status: ENROLLING_BY_INVITATION
Conditions: Multiple Myeloma|Smoldering Multiple Myeloma
Interventions: DRUG: Carfilzomib|DRUG: Lenalidomide|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation the Association of Microbiome Between Respiratory Tract Samples and Stool Samples in Pneumonic Patients Accompanied by Respiratory Failure
Status: COMPLETED
Conditions: Microbiota|Pneumonia, Bacterial|Respiratory Failure|Lower Resp Tract Infection
Interventions: DIAGNOSTIC_TEST: 16s RNA sequence of sputum, bronchoalveolar lavage fluid (options), stool
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p