pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Study of Efficacy and Safety of Ociperlimab in Combination With Tislelizumab and Platinum-based Doublet Chemotherapy as First-line Treatment for Participants With Locally Advanced or Metastatic NSCLC.
Status: WITHDRAWN
Conditions: Non-small Cell Lung Cancer (NSCLC)
Interventions: DRUG: Ociperlimab|DRUG: Placebo|DRUG: Tislelizumab|DRUG: Pembrolizumab|DRUG: Carboplatin|DRUG: Cisplatin|DRUG: Pemetrexed|DRUG: Paclitaxel|DRUG: Nab-paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Optimizing Regulation of a Cochlear Implant in Patients With Functional Contralateral Audition.
Status: COMPLETED
Conditions: Functional Contralateral Audition|Cochlear Implant
Interventions: OTHER: audiometric tests|OTHER: Questionnaires|OTHER: Settings of cochlear implants
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: TBS in Major Depression
Status: UNKNOWN
Conditions: Treatment Resistant Depression
Interventions: DEVICE: theta-burst stimulation (TBS) using a MagPro X1000|DEVICE: theta-burst stimulation (TBS) using a MagPro X1000
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Early Hospital Discharge or Standard Inpatient Care in Cancer Patients Receiving Antibiotics for Febrile Neutropenia
Status: UNKNOWN
Conditions: Brain and Central Nervous System Tumors|Lymphoma|Neutropenia|Psychosocial Effects of Cancer and Its Treatment|Small Intestine Cancer|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: amoxicillin-clavulanate potassium|DRUG: ciprofloxacin|PROCEDURE: psychosocial assessment and care|PROCEDURE: quality-of-life assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Anatomic and Biomechanical Investigation on ACL: A Cadaveric Study
Status: UNKNOWN
Conditions: Anterior Cruciate Ligament Rupture
Interventions: PROCEDURE: round tunnel|PROCEDURE: flat tunnel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase Ib Study of LDK378 and AUY922 in ALK-rearranged Non-small Cell Lung Cancer
Status: COMPLETED
Conditions: Anaplastic Lymphoma Kinase (ALK)|Non-small Cell Lung Cancer
Interventions: DRUG: LDK378|DRUG: AUY922
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Intraperitoneal Bupivacaine Versus Bupivacaine With Neostigmine on Pain in Laparoscopic Cholecystectomy
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: DRUG: Bupivacaine Hydrochloride|DRUG: Neostigmine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Study to Investigate the Safety, Tolerability and Pharmacokinetics of AD 452 [(+)-Mefloquine] Compared With Racemic Mefloquine
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: AD 452 (+) mefloquine|DRUG: Racemic Mefloquine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Early Occupational Therapy in Mechanical Ventilated Patients With Covid-19
Status: UNKNOWN
Conditions: Covid19|Critical Illness|Impairment, Cognitive|Impairment, Coordination
Interventions: BEHAVIORAL: Early Occupational Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial to Investigate the Safety, Tolerability, Pharmacokinetics, and Food Effect of PMK-S005 After Oral Administration in Healthy Male Volunteers
Status: COMPLETED
Conditions: Gastritis|Gastric Ulcer
Interventions: DRUG: PMK-S005
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Palliative Radiotherapy and Brachytherapy for Oesophageal Cancer Dysphagia
Status: COMPLETED
Conditions: Esophageal Cancer
Interventions: RADIATION: Protracted Course Radiotherapy|RADIATION: Short Course Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ramipril in Pediatric Patients on Hemodialysis
Status: COMPLETED
Conditions: Hemodialysis
Interventions: DRUG: Ramipril|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PETHEMA LAL-RI/96: Treatment for Patients With Standard Risk Acute Lymphoblastic Leukemia
Status: COMPLETED
Conditions: Acute Lymphoblastic Leukemia
Interventions: DRUG: Asparaginase|DRUG: Cyclophosphamide|DRUG: Cytarabine|DRUG: Daunorubicin|DRUG: Mercaptopurine|DRUG: Prednisone|DRUG: Vincristine|DRUG: Methotrexate|PROCEDURE: Intrathecally treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diastolic Dysfunction PPCM in Patients With Documented Left Ventricular Systolic Function Recovery
Status: WITHDRAWN
Conditions: Peripartum Cardiomyopathy|Diastolic Dysfunction
Interventions: DIAGNOSTIC_TEST: A clinical Transthoracic echocardiogram
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study To Evaluate The Efficacy Of Tofacitinib In Moderate To Severe Alopecia Areata, Totalis And Universalis
Status: COMPLETED
Conditions: Alopecia Areata
Interventions: DRUG: Tofacitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Venetoclax and Ibrutinib in Treating Patients With Chronic or Small Lymphocytic Leukemia
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Lymphocytic Leukemia|Recurrent Chronic Lymphocytic Leukemia|Recurrent Small Lymphocytic Lymphoma|Refractory Chronic Lymphocytic Leukemia|Refractory Small Lymphocytic Lymphoma|Small Lymphocytic Lymphoma
Interventions: DRUG: Ibrutinib|OTHER: Laboratory Biomarker Analysis|DRUG: Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Test How a New Long-acting Insulin (Insulin Icodec) Works in the Body of People With Liver Disease
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Insulin icodec
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PROGRESSive Withdrawal Esomeprazole and Acid-related Symptoms
Status: ACTIVE_NOT_RECRUITING
Conditions: Stomach Diseases
Interventions: DRUG: Esomeprazole: Nexium® 20mg, Astra Zeneca|OTHER: CYP2C19 phenotypical analysis|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Lactobacillus Reuteri for Treatment of Uncomplicated UTI in Pregnant Women
Status: COMPLETED
Conditions: Urinary Tract Infection in Pregnancy
Interventions: DIETARY_SUPPLEMENT: Probiotics|DRUG: Antibiotics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Drug Trial in Healthy Male Subjects to Determine and Compare the Blood Concentrations of BI 144807 Following Administration as Oral Solution and Tablet Under Fasted and Fed Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BI 144807 high dose|DRUG: BI 144807 intermediate dose|DRUG: BI 144807 intermediate dose|DRUG: BI 144807 intermediate dose|DRUG: BI 144807 intermediate dose|DRUG: BI 144807 intermediate dose|DRUG: BI 144807 high dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Functional Impact of Reconstructive Surgery by Harvesting a Vascularized Free Fibula Flap Postoperatively.
Status: RECRUITING
Conditions: Bone Reconstruction by Free Fibula Flap
Interventions: OTHER: Actimetric measurement|OTHER: Evaluation of plantar flexion, dorsal flexion and ankle eversion forces|OTHER: Assessment of static and dynamic balance and quality of life|OTHER: Functional gait assessment (TM6)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Dose-escalation Study of Oral Administration of S 55746 in Patients With Chronic Lymphocytic Leukaemia and B-Cell Non-Hodgkin Lymphoma
Status: COMPLETED
Conditions: Chronic Lymphocytic Leukaemia (CLL)|B-Cell Non-Hodgkin Lymphoma (NHL)|Multiple Myeloma (MM)
Interventions: DRUG: S 55746
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chidamide With ICE Regimen for Relapsed/Refractory Peripheral T Cell Lymphoma
Status: UNKNOWN
Conditions: Peripheral T Cell Lymphoma
Interventions: DRUG: Chidamide with ICE regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Laparoscopic Single Anastomosis Sleeve Ileal Bypass Versus Laparoscopic Sleeve Gastrectomy for Morbid Obesity
Status: RECRUITING
Conditions: Obesity, Morbid
Interventions: PROCEDURE: Single anastomosis sleeve ileal bypass|PROCEDURE: Sleeve gastrectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Pregnancy Exposure Registry for Vumerity (Diroximel Fumarate)
Status: RECRUITING
Conditions: Multiple Sclerosis
Interventions: DRUG: Diroximel Fumarate|DRUG: Avonex|BIOLOGICAL: Tysabri|DRUG: Dimethyl Fumarate
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Use of Vagitories Based on St. John's Wort, Tea Tree Oil and Shepherd's Purse in the Treatment of Vaginal Inflammation
Status: COMPLETED
Conditions: Non Specific Vaginitis
Interventions: DRUG: Shepherd's Purse extractum oleosum vagitories|DRUG: Tea tree oil vagitories|DRUG: Hyperici extractum oleosum vagitories|DRUG: Vagitories - Probiotic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Accessibility of the World Health Organization's eTB Catalogue of Recommendations
Status: COMPLETED
Conditions: Tuberculosis
Interventions: OTHER: eTB Catalogue of Recommendations (eTB)|OTHER: World Health Organization Tuberculosis Website (WHO TB)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Efficacy of Pulsed Dye Laser in Dermatophytosis
Status: COMPLETED
Conditions: Cutaneous Dermatophytosis|Pulsed Dye Laser
Interventions: DEVICE: pulsed dye (585nm) laser therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Management of Castration-Resistant Prostate Cancer With Oligometastases
Status: RECRUITING
Conditions: Castration-resistant Prostate Cancer Patients With Oligometastases
Interventions: DRUG: Leuprolide Acetate|DRUG: Goserelin Acetate|DRUG: Triptorelin|DRUG: Enzalutamide|RADIATION: Stereotactic Body Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Using Tissue-based Spatial Data to Understand How Obesity-related Tumor Metabolites Fuel Prostate Cancer Progression
Status: RECRUITING
Conditions: Prostate Cancer|Prostate Adenocarcinoma|Prostate Neoplasm|Prostatic Neoplasm|Obesity
Interventions: OTHER: observational study
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Zinc Supplementation Effect on Immune Recovery in HIV Patients
Status: UNKNOWN
Conditions: HIV|AIDS|Immunological Deficiency|Inadequate Immune Recovery|Viral Replication
Interventions: DIETARY_SUPPLEMENT: Zinc supplementation|DIETARY_SUPPLEMENT: Placebo supplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: ESP Block in Pediatric Patients for Postoperative Analgesia
Status: COMPLETED
Conditions: Opioid Use|Pain, Postoperative|Quality of Life
Interventions: DRUG: Bupivacain|DRUG: saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Observational Study Examining the Use of Triple Combination Therapy With Boceprevir, Peginterferon Alfa-2a and Ribavirin in the Re-Treatment of Chronic Hepatitis C Patients
Status: TERMINATED
Conditions: Hepatitis C, Chronic
Interventions: DRUG: Boceprevir|DRUG: Simeprevir|DRUG: Pegylated Interferon (Peginterferon) Alfa-2a|DRUG: Ribavirin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Investigation of AlzHeimer's Predictors in Subjective Memory Complainers - Extension Study
Status: NOT_YET_RECRUITING
Conditions: Alzheimer Disease|Memory Complaint|Memory Disorders
Interventions: PROCEDURE: Electroencephalogram (EEG)|PROCEDURE: Oculomotor tests|PROCEDURE: MRI|RADIATION: 18-F amyloid PET Scan|RADIATION: 18F-fluorodeoxyglucose (FDG) PET Scan|BIOLOGICAL: Blood sampling|BIOLOGICAL: Lumbar puncture
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Pain Relief Intervention of Meditation in Renal Disease (PRIMER)
Status: COMPLETED
Conditions: Chronic Kidney Diseases|Renal Disease|Chronic Kidney Failure|End Stage Renal Disease
Interventions: BEHAVIORAL: Mindfulness-Based Stress Reduction
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Understanding Reactions to Emotional Material in the Media During COVID-19
Status: COMPLETED
Conditions: Healthy Participants|Intrusive Memories
Interventions: BEHAVIORAL: Simple cognitive task intervention|BEHAVIORAL: Attention Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Adherence, Viability, Clinical Evolution and Therapeutic Efficacy in Patients Undergoing Bone Marrow Transplantation
Status: ENROLLING_BY_INVITATION
Conditions: Stem Cell Transplantation
Interventions: DEVICE: Cycle ergometer|DEVICE: Strength Training - elastic band and shin guards|DEVICE: Cycle ergometer, elastic band and shin guards
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Clarithromycin and Rifabutin for the Treatment of M. Avium Complex (MAC) Lung Disease
Status: COMPLETED
Conditions: Mycobacterium Avium Complex Lung Disease
Interventions: DRUG: clarithromycin, rifabutin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Granulomatous and Lymphocytic Interstitial Lung Disease in Patients With Common Variable Immunodeficiency
Status: WITHDRAWN
Conditions: Granulomatous and Lymphocytic Interstitial Lung Disease
Interventions: DRUG: Rituximab (RTX) and Azathioprine (AZA)|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase III Study Comparing 3D Conformal Radiotherapy and Conformal Radiotherapy IMRT to Treat Endometrial Cancer
Status: TERMINATED
Conditions: Endometrial Cancer
Interventions: RADIATION: 3D conformational radiation|RADIATION: IMRT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Do Terpenes Play a Role in the Stress-reducing Effects of a Forest Bathing Intervention?
Status: RECRUITING
Conditions: Monoterpene Exposure During a Forest Bathing Intervention
Interventions: BEHAVIORAL: Forest bathing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Very Early Mobilization of Colorectal Surgery Patients
Status: COMPLETED
Conditions: Postoperative Care|Colorectal Surgery
Interventions: OTHER: Very early mobilization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Genicular Artery Embolization for the Treatment of Knee Osteoarthritis
Status: COMPLETED
Conditions: Knee Osteoarthritis|Degenerative Joint Disease of Knee
Interventions: DEVICE: Embozene MicroSpheres
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study in Myeloma Patients Newly Diagnosed Treated as an Induction With Velcade-Dex or Velcade (Bortezomib) Thalidomide Dexamethasone (VTD)
Status: UNKNOWN
Conditions: Multiple Myeloma
Interventions: DRUG: Velcade-Dexamethasone|DRUG: Velcade-Thalidomide-Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Cariprazine Study in the Prevention of Relapse in Bipolar I Disorder Patients Whose Current Episode is Manic or Depressive, With or Without Mixed Features
Status: COMPLETED
Conditions: Bipolar I Disorder|Mania|Depression
Interventions: DRUG: Cariprazine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Efficacy of Human Recombinant Factor VIII (Kogenate FS) Reconstituted in Pegylated Liposomes.
Status: COMPLETED
Conditions: Haemophilia A
Interventions: DRUG: Kogenate FS, reconstituted in a suspension of liposomes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of the Vaginal Colonization of Two New Lactobacillus Strains After Oral Administration in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Experimental 1|DIETARY_SUPPLEMENT: Experimental 2|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A PHASE I, RANDOMIZED, PLACEBO-CONTROLLED, SINGLE DOSE ESCALATION STUDY TO INVESTIGATE SAFETY, PHARMACOKINETICS AND PHARMACODYNAMICS OF SHR0534 IN HEALTHY VOLUNTEERS
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: SHR0534|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Late Surfactant After a Recruitment Maneuver in Extremely Low Gestational Age Newborns - LATE-REC-SURF Trial
Status: RECRUITING
Conditions: Bronchopulmonary Dysplasia|Chronic Pulmonary Insufficiency of Prematurity
Interventions: DRUG: Poractant Alfa Intratracheal Suspension [Curosurf]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Does Fampridine SR Improve Cognitive Fatigue in Multiple Sclerosis Patients?
Status: COMPLETED
Conditions: Cognitive Fatigue
Interventions: DRUG: Fampridine SR|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Chamomile Effect on Xerostomia Associated With End-stage Renal Disease in Elderly
Status: COMPLETED
Conditions: Xerostomia Due to Hyposecretion of Salivary Gland
Interventions: OTHER: Chamomile|OTHER: Saline mouthwash
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Correlation Between Pain and Emergence Delirium After Adenotonsillectomy in Preschool Children
Status: COMPLETED
Conditions: Adenotonsillectomy|Postoperative Pain|Emergence Delirium
Interventions: DRUG: Sevoflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study to Assess the Efficacy and Safety of LYS006 in Patients With Moderate to Severe Inflammatory Acne
Status: COMPLETED
Conditions: Inflammatory Acne
Interventions: DRUG: LYS006 20 mg|DRUG: LYS006 2 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Terrestrial Trunked Radio (TETRA) and Cognitive Functions in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: RADIATION: low RF exposure level|RADIATION: sham exposure|RADIATION: high RF exposure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of a Recombinant Coronavirus-Like Particle COVID-19 Vaccine in Adults
Status: ACTIVE_NOT_RECRUITING
Conditions: SARS-CoV-2 Infection
Interventions: DRUG: Intramuscular injection|BIOLOGICAL: Intramuscular vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: QUICKly Eradicate Hepatitis C in Patients Undergoing REnal Transplant With 4 Weeks of Glecaprevir/Pibrentasvir
Status: COMPLETED
Conditions: Kidney Failure|Hepatitis C|Kidney Disease, Chronic
Interventions: DRUG: Glecaprevir and Pibrentasvir
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Statin Therapy in the Treatment of Sepsis
Status: COMPLETED
Conditions: Septic Shock
Interventions: DRUG: Simvastatin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ibrutinib After Intensive Induction in Treating Patients With Previously Untreated Mantle Cell Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Contiguous Stage II Mantle Cell Lymphoma|Noncontiguous Stage II Mantle Cell Lymphoma|Stage I Mantle Cell Lymphoma|Stage III Mantle Cell Lymphoma|Stage IV Mantle Cell Lymphoma
Interventions: DRUG: ibrutinib|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Endocrine Therapy in Breast Cancer. Real Clinical Practice in Russia
Status: RECRUITING
Conditions: Breast Cancer|Neoadjuvant Endocrine Therapy
Interventions: DRUG: Tamoxifen 20mg|DRUG: Anastrozole 1mg|DRUG: Letrozole 2.5mg|DRUG: Goserelin|DRUG: Triptorelin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Zanubrutinib in Maintenance Therapy of DLBCL Patients With Initial Remission
Status: NOT_YET_RECRUITING
Conditions: Diffuse Large B-cell Lymphoma (DLBCL)
Interventions: DRUG: Zanubrutinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility and Effectiveness of tDCS in the Treatment of Post-stroke Fatigue (EFECTS).
Status: ACTIVE_NOT_RECRUITING
Conditions: Stroke
Interventions: DEVICE: tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Subjective and Objective Refraction in Pseudophakic Patients
Status: COMPLETED
Conditions: Pseudophakia
Interventions: DEVICE: Subjective refraction|DEVICE: Autorefraction|DEVICE: Wavefront aberrometry
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Investigator Sponsored Trial of Polypoidal Choroidal Vasculopathy (PCV) Evaluation Assessing High-Dose Ranibizumab Prospectively (PEARL2)
Status: COMPLETED
Conditions: PCV|Polypoidal Choroidal Vasculopathy
Interventions: DRUG: high-dose ranibizumab|DRUG: ranibizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BABY STEPS II: SMS Scheduled Gradual Reduction Text Messages to Help Pregnant Smokers Quit
Status: COMPLETED
Conditions: Smoking|Pregnancy
Interventions: BEHAVIORAL: Scheduled Gradual Reduction Text Messages|BEHAVIORAL: Support Text Messages
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: 3 Years Clinical Evaluation of 3D Printed Resin Composite Fixed Dental Prosthesis
Status: UNKNOWN
Conditions: Composite Resins|Dental Prosthesis
Interventions: DEVICE: ELS Even Stronger (3D Printed Resin Composite)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EGF-loaded Chitosan to Facilitate Healing and Prevent Scar Formation of Cesarean Wound
Status: COMPLETED
Conditions: Cesarean Wound|Scar; Previous Cesarean Section, Complicating Pregnancy or Childbirth, Affecting Fetus or Newborn
Interventions: OTHER: Control|OTHER: Silicone gel|OTHER: microencapsulated polysaccharide and oligopeptide-1(Me-EGF) 40 mcg & 5 mcg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Habitual Hypertension Medication Adherence in Arizona
Status: COMPLETED
Conditions: Medication Adherence|Habits|Hypertension
Interventions: OTHER: Wellth app|BEHAVIORAL: Habit training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Dexamethasone/ Erector Spinae Plane Block Analgesia in Laparoscopic Cholecystectomy
Status: UNKNOWN
Conditions: Post Operative Pain
Interventions: DRUG: Dexamethasone/ Erector Spinae Plane Block|DRUG: Erector Spinae Plane Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Digital Behavioral Interventions in Inflammatory Bowel Disease
Status: COMPLETED
Conditions: Crohn Disease|Ulcerative Colitis|Inflammatory Bowel Diseases|Stress, Psychological|Depression, Anxiety
Interventions: BEHAVIORAL: Internet based cognitive behavioral therapy|BEHAVIORAL: Digital mood tracking
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparison of BMS-232632 With Efavirenz, Each in Combination With Zidovudine-Lamivudine
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Atazanavir|DRUG: Lamivudine/Zidovudine|DRUG: Efavirenz
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Calorie Restricted MediterrAsian Diet on Weight Loss in FTO rs9939609 Overweight Carriers
Status: COMPLETED
Conditions: Obesity|Dietary Modification
Interventions: BEHAVIORAL: MediterrAsian diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Pharmacokinetics, Safety and Tolerability of CHF 5993 pMDI in Subjects With Renal Impairment.
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: DRUG: Beclometasone/Formoterol/Glycopyrrolate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of VMP001 and AS01B (Adjuvant Formulation) in Healthy Malaria-Naïve Adults
Status: COMPLETED
Conditions: Malaria|Plasmodium Vivax
Interventions: BIOLOGICAL: VMP001|OTHER: P. vivax sporozoite challenge
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Bioequivalence Study Comparing Irbesartan/Atorvastatin Combination Tablet With Coadministration of Irbesartan and Atorvastatin
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: HCP0912 / Irbesartan and Atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Behavioral Activation Delivered Via Home-based Telehealth to Improve Functioning in Cardiovascular Disease Patients Recently Discharged From Inpatient Care
Status: RECRUITING
Conditions: Depression|Cardiovascular Diseases
Interventions: BEHAVIORAL: BA-HT|OTHER: Standard Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of RC28-E Versus Aflibercept
Status: RECRUITING
Conditions: Wet Age-related Macular Degeneration
Interventions: DRUG: RC28-E|DRUG: Aflibercept
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Efficacy of PKU Synergy in Patients Expressing Phenylketonuria or Hyperphenylalaninemia
Status: COMPLETED
Conditions: Phenylketonurias|Hyperphenylalaninaemia, Type I
Interventions: DIETARY_SUPPLEMENT: Synergy|OTHER: Routine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Host Dendritic Cells in Allograft Patients
Status: UNKNOWN
Conditions: Relapsed Non-Hodgkin's Lymphoma|Hodgkin's Disease|Multiple Myeloma|Chronic Lymphocytic Lymphoma
Interventions: BIOLOGICAL: MSSM/BIIR HDC Vax-001 (Host Dendritic Cells)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Integrated Community Case Management Study in Eastern Province, Zambia
Status: UNKNOWN
Conditions: Malaria|Diarrhea|Pneumonia
Interventions: OTHER: mHealth inventory management|OTHER: Supportive supervision|OTHER: ICCM current standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Pembrolizumab After ASCT for Hodgkin Lymphoma, DLBCL and T-NHL
Status: COMPLETED
Conditions: Hodgkin Lymphoma|Diffuse Large B Cell Lymphoma|Peripheral T-Cell Lymphoma
Interventions: DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Synergism Or Long Duration (SOLD) Study
Status: COMPLETED
Conditions: Breast Neoplasms
Interventions: DRUG: trastuzumab (9 weeks) + docetaxel|DRUG: trastuzumab (9 weeks) + docetaxel + CEF + trastuzumab (up to 51 weeks)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Study of Milrinone in Babies With Persistent Pulmonary Hypertension of the Newborn
Status: TERMINATED
Conditions: Persistent Fetal Circulation Syndrome
Interventions: DRUG: Milrinone Lactate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Safety, Pharmacokinetics, and Pharmacodynamics of INS1007 in Healthy Japanese and Caucasian Participants
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: INS1007|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Relationship Between Endoplasmic Reticulum Stress and Pain in Patients With Endometriosis
Status: COMPLETED
Conditions: Endometriosis|Endoplasmic Reticulum Stress|Endometriosis-related Pain
Interventions: OTHER: xbp-1 - endometriosis patients group
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Fed Study of Nadolol/Bendroflumethiazide Tablets 80 mg/5 mg and Corzide® Tablets 80 mg/5 mg
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Nadolol/Bendroflumethiazide Tablets 80 mg/5 mg|DRUG: Corzide® Tablets 80 mg/5 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Oxytocin and Social Cognition in Schizophrenia
Status: COMPLETED
Conditions: Social Cognition|Social Anxiety|Emotional Intelligence
Interventions: DRUG: Oxytocin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Benefits of B-Flow Ultrasound
Status: COMPLETED
Conditions: Evidence of Liver Transplantation|Arterial Occlusive Diseases|Hypertension|Pregnancy, High Risk|Pregnancy
Interventions: DEVICE: GE LOGIQ E9 Ultrasound System
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: "Impact of Kangaroo Mother Care Plus Massage Therapy on Growth of Preterm Low Birth Weight Infants at Discharge"
Status: ENROLLING_BY_INVITATION
Conditions: Weight Gain
Interventions: BEHAVIORAL: KMC with Massage therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Phase 2 Study Evaluating The Efficacy And Safety Of PF 04494700 In Mild To Moderate Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: PF-04494700|DRUG: PF-04494700|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ligation and Hemorrhoidopexy Technique Versus Ligation of Hemorrhoidal Arteries Using Ultrasound for Hemorrhoids
Status: COMPLETED
Conditions: Hemorrhoids
Interventions: PROCEDURE: Ligation and Hemorrhoidopexy|PROCEDURE: Ultrasound Guided Ligation of Hemorrhoidal Arteries
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Conventional Versus Left Bundle Branch Pacing in TAVI
Status: NOT_YET_RECRUITING
Conditions: Aortic Valve Stenosis|Heart Failure|Pacemaker-Induced Cardiomyopathy|Transcatheter Aortic Valve Implantation
Interventions: DEVICE: Left bundle branch pacemaker|DEVICE: Conventional pacing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Peripheral Stem Cell Transplantation Plus Combination Chemotherapy and Monoclonal Antibody Therapy in Treating Patients With Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: BIOLOGICAL: filgrastim|BIOLOGICAL: rituximab|BIOLOGICAL: sargramostim|DRUG: carmustine|DRUG: cisplatin|DRUG: cyclophosphamide|DRUG: dexamethasone|DRUG: etoposide|DRUG: gemcitabine hydrochloride|DRUG: melphalan|DRUG: paclitaxel|PROCEDURE: bone marrow ablation with stem cell support|PROCEDURE: peripheral blood stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Effect of Red Clover on Menopause Symptoms and Lipid Profile
Status: COMPLETED
Conditions: Menopause
Interventions: DIETARY_SUPPLEMENT: red clover
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Non-invasive Diagnostics of Iron Deficiency in Surgical Patients by Measuring Zinc Protoporphyrin-IX
Status: COMPLETED
Conditions: Iron-deficiency|Anemia|Iron Deficiency Anemia
Interventions: DIAGNOSTIC_TEST: Non-invasive analysis of Zinc protoporphyrin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Cold Application and Heparinoid on Periorbital Edema and Ecchymosis
Status: COMPLETED
Conditions: Neurological Disorder|Nursing Caries|Periorbital Edema|Ecchymosis|Cryotherapy Effect
Interventions: OTHER: Routine care|OTHER: Cold gel pack|DRUG: Heparinoids Topical Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Audition After a Lesion and in Migraine. (AuditionPostLesion)
Status: COMPLETED
Conditions: Migraine Disorders, Brain
Interventions: OTHER: Neuropsychological tests|OTHER: Neurophysiological tests
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Boosting Performance: The Power of Cranberry Supplementation
Status: COMPLETED
Conditions: Oxygen Consumption|Mitochondria|Blood Flow|Aerobic Capacity
Interventions: DIETARY_SUPPLEMENT: Cranberry extract
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Internet Treatment for Weight Loss in Primary Care
Status: COMPLETED
Conditions: Overweight|Obese
Interventions: BEHAVIORAL: Motivational Interviewing|BEHAVIORAL: Nutritional Counseling|BEHAVIORAL: Treatment as usual with primary care physician
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Carotid Flow Time Measurement Guided Fluid Management During Spinal Anesthesia
Status: UNKNOWN
Conditions: Meniscus Disorder
Interventions: OTHER: Group Carotis FTc 500 ml "Ringer's lactate" Lafleks®|OTHER: Group Preloading 10 ml/kg "Ringer's lactate" Lafleks®|OTHER: Group Control 2 ml/kg "Ringer's lactate" Lafleks®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Melatonin's Effects on Treatment Of Diabetes Mellitus
Status: UNKNOWN
Conditions: Diabetes Mellitus
Interventions: DRUG: Melatonin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Emotion Regulation Strategies Used When Suicidal
Status: RECRUITING
Conditions: Suicidal Ideation|Treatment Refusal|Emotion Regulation
Interventions: BEHAVIORAL: Crisis Response Planning and Lethal Means Safety Counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cardiac Autonomic Changes After Endoscopic Thoracic Sympathectomy For Essential Palmar Hyperhidrosis
Status: COMPLETED
Conditions: Hyperhidrosis
Interventions: PROCEDURE: Sympathectomy|PROCEDURE: Sympathicotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of LY3039478 in Participants With Advanced Cancer
Status: COMPLETED
Conditions: Neoplasms|Neoplasm Metastasis|Lymphoma
Interventions: DRUG: LY3039478|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Performance and Safety of Bone Substitute MBCP-FS in Maxillary Sinus Lift Procedures
Status: COMPLETED
Conditions: Sinus Implant Reconstruction
Interventions: DEVICE: Macroporous Biphasic Calcium Phosphate-Fibrin Sealant Vapor Heated Solvent/Detergent Treated 4 IU/ML Thrombin (MBCP-FS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Intensive Insulin Therapy for Strict Glycemic Control in Neurosurgical Patients: Safety and Efficacy
Status: UNKNOWN
Conditions: Subarachnoid Hemorrhage|Traumatic Brain Injury|Intracranial Hemorrhage
Interventions: DRUG: Insulin (Actrapid)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Complex Exercises of the Respiratory Muscles Plus Aerobic Training vs. Aerobic Training in Patients With СHF
Status: COMPLETED
Conditions: Heart Failure
Interventions: OTHER: respiratory muscles training|OTHER: sham respiratory muscles training|OTHER: aerobic training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Impact of a Case-finding Strategy for Vertebral Fractures
Status: COMPLETED
Conditions: Osteoporosis|Vertebral Fracture
Interventions: PROCEDURE: Clinical assessment +/- radiography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Palliative Expeditiously Adaptive Quad Shot Radiation Therapy (PEAQ-RT)
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: DEVICE: Ring gantry kV-CBCT combined with linear accelerator (Halcyon)|RADIATION: Quad shot radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Effect of the Level of Dietary Protein on Infant Growth
Status: COMPLETED
Conditions: Infant Nutrition
Interventions: OTHER: Standard infant formula|OTHER: Infant formula with different level of proteins
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: After Surgery Acute Renal Failure Incidence in Total Knee Arthroplasty With and Without Tourniquet
Status: COMPLETED
Conditions: Arthroplasty, Replacement, Knee|Acute Kidney Injury|Tourniquets|Knee Osteoarthritis
Interventions: PROCEDURE: total knee arthroplasty|PROCEDURE: Tourniquet limb cuff|DRUG: Intaarticular lidocain
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy of SPD465 in Adults With ADHD
Status: COMPLETED
Conditions: Attention Deficit Disorder With Hyperactivity
Interventions: DRUG: Neutral salts of dextroamphetamine sulfate, USP, amphetamine sulfate, USP, d-amphetamine saccharate, d,I-amphetamine aspartate monohydrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: LAL-Ph-2000: Treatment of Acute Lymphoblastic Leukemia Chromosome Philadelphia Positive
Status: COMPLETED
Conditions: Acute Lymphoblastic Leukemia
Interventions: DRUG: Vincristine|DRUG: Daunorubicin|DRUG: Prednisone|DRUG: L-Asparaginase|DRUG: Mitoxantrone|DRUG: Cytosine Arabinoside|DRUG: Hydrocortisone|DRUG: Mercaptopurine|DRUG: Cyclophosphamide|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study The Effects Of Different Doses Of UK-369,003 In Men With Overactive Bladder
Status: COMPLETED
Conditions: Urinary Bladder, Overactive
Interventions: DRUG: UK-369,003|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Epimedium Prenylflavonoid (EP) Extract for Osteoporosis and Cardiovascular Disease
Status: UNKNOWN
Conditions: Osteoporosis|Cardiovascular Disease
Interventions: DRUG: Epimedium Prenylflavonoids Extract|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bispectral Index Monitoring In Pediatric Cataract Surgery: A Comparative Study Using Propofol-Midazolam Versus Sevoflurane Anesthesia
Status: COMPLETED
Conditions: Ophthalmic
Interventions: OTHER: measuring depth of anesthesia and its relation to the globe
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phase I Trial of Endoxifen Gel Versus Placebo in Women Undergoing Breast Surgery
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Ductal Carcinoma In Situ|Breast Lobular Carcinoma In Situ|Stage 0 Breast Cancer AJCC v6 and v7|Stage I Breast Cancer AJCC v7|Stage IA Breast Cancer AJCC v7|Stage IB Breast Cancer AJCC v7|Stage II Breast Cancer AJCC v6 and v7|Stage IIA Breast Cancer AJCC v6 and v7|Stage IIB Breast Cancer AJCC v6 and v7|Stage III Breast Cancer AJCC v7|Stage IIIA Breast Cancer AJCC v7|Stage IIIB Breast Cancer AJCC v7|Stage IIIC Breast Cancer AJCC v7
Interventions: DRUG: Endoxifen Hydrochloride|OTHER: Placebo Administration|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION