pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Changes in Prostaglandin Levels in Laser Cataract Surgery (LCS) Subject to Laser Prevalence
Status: UNKNOWN
Conditions: Age Related Cataracts
Interventions: DEVICE: Femtosecondlaser-assisted|PROCEDURE: Anterior Capsulotomy|PROCEDURE: Lens Fragmentation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Melatonin on Sleep and Ventilatory Control in Obstructive Sleep Apnea
Status: COMPLETED
Conditions: Obstructive Sleep Apnea
Interventions: DIETARY_SUPPLEMENT: Melatonin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Family Caregiver Ambassador Support for Family Caregivers of Patients With Hematological Disease
Status: COMPLETED
Conditions: Multiple Myeloma|Lymphoma|Bone Marrow Transplantation|Neoplasms|Hematologic Diseases|Leukemia, Myeloid
Interventions: OTHER: Family Caregiver Ambassador Support
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effectiveness of Neuromuscular Kinesiology Taping in Plantar Fasciitis
Status: COMPLETED
Conditions: Fasciitis, Plantar
Interventions: OTHER: Kinesiotaping|OTHER: Tape
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Recovery Benefits After Treatment With Parecoxib/Valdecoxib in Patients Undergoing Abdominal Surgery
Status: TERMINATED
Conditions: Pain
Interventions: DRUG: Parecoxib/Valdecoxib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study of Sivelestat Sodium to Shorten Mechanical Ventilation in Acute Aortic Dissection
Status: NOT_YET_RECRUITING
Conditions: Acute Aortic Dissection
Interventions: DRUG: Sivelestat sodium was given intravenously|DRUG: Placebo was given intravenously
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Surgery Vs Chemoradiation for Oropharyngeal Cancer- A Phase II/III Integrated Design Randomized Control Trial
Status: NOT_YET_RECRUITING
Conditions: Stage III Oropharyngeal (p16-Negative) Carcinoma AJCC v8|Stage IV Oropharyngeal (p16-Negative) Carcinoma AJCC v8
Interventions: PROCEDURE: Surgery with or without Neck Dissection|RADIATION: Radiation|DRUG: Cisplatin based chemotherpay
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of Chemotherapy for HPV-Associated Oropharyngeal Cancer
Status: COMPLETED
Conditions: Oropharyngeal Squamous Cell Carcinoma
Interventions: OTHER: Transoral Robotic Surgery (TORS) or Radiotherapy|OTHER: Chemotherapy and Low-Dose Radiotherapy|OTHER: Chemotherapy and High-Dose Radiotherapy|DRUG: Paclitaxel|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Corneal Endothelial Cell Loss After Trabeculectomy Versus Phakotrabeculectomy
Status: COMPLETED
Conditions: Corneal Endothelial Cell Loss|Glaucoma
Interventions: PROCEDURE: Trabeculectomy|PROCEDURE: Phako-trabeculectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Dose-Escalation Safety Study of HPN-100 to Treat Urea Cycle Disorders
Status: COMPLETED
Conditions: Urea Cycle Disorders
Interventions: DRUG: HPN-100|DRUG: BUPHENYL®
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Effect of Rifampicin on the Uptake and Breakdown of ACT-246475 in Healthy Subjects
Status: COMPLETED
Conditions: Healthy Subject
Interventions: DRUG: Saline|DRUG: ACT-246475|DRUG: Rifampicin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Effect of Moderate Caloric Restriction on Glomerular Growth After Kidney Transplantation
Status: TERMINATED
Conditions: Kidney Transplant; Complications|Glomerular Disease|Weight Gain|Kidney Transplant
Interventions: BEHAVIORAL: caloric intake reduction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Impact of a Brief Motivational Intervention Including Counter-marketing Arguments With a Population of Patients With Moderate to Severe Alcohol Use Disorders Who Are Followed up on an Outpatient Basis (Primary Care or Addictology) (DEPREV_Phase 3)
Status: TERMINATED
Conditions: Addiction, Alcohol
Interventions: OTHER: Motivational interview|OTHER: Routine Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Treatment of Social Phobia With Combined Cognitive Bias Modification and iCBT
Status: COMPLETED
Conditions: Social Phobia
Interventions: BEHAVIORAL: Internet-administered cognitive behavioral therapy (iCBT)|BEHAVIORAL: Cognitive bias modification training program variant 1|BEHAVIORAL: Cognitive bias modification training program variant 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of Brief-tele Support on Attendance at Physiotherapy Sessions
Status: RECRUITING
Conditions: Pelvic Floor Dysfunctions
Interventions: BEHAVIORAL: Pre-letter telephone call.|BEHAVIORAL: Post-letter telephone call
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Clinical Performance Evaluation of Two Frequent Replacement Silicone Hydrogel Toric Contact Lenses
Status: COMPLETED
Conditions: Ametropia|Myopia|Hyperopia|Astigmatism
Interventions: DEVICE: Serafilcon A toric contact lenses|DEVICE: Senofilcon A toric contact lenses|DEVICE: CLEAR CARE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Effect of Tiotropium on Exercise Tolerance in Patients With Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Tiotropium inhalation capsules|DRUG: Placebo inhalation capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intraocular Pressure (IOP) Lowering Effect of Selective Laser Trabeculoplasty Versus Prostaglandin Analogues in Angle Closure Glaucoma
Status: UNKNOWN
Conditions: Glaucoma
Interventions: PROCEDURE: Selective Laser Trabeculoplasty|DRUG: Travoprost/ Timolol/ Azopt/ Brimonidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose Response and Receptor Selectivity of Beta-blocker Effects on Bone Metabolism
Status: COMPLETED
Conditions: Osteoporosis, Age-Related
Interventions: DRUG: Atenolol|DRUG: Nebivolol|DRUG: Propranolol|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect of Combined PRP and ESWT for Carpal Tunnel Syndrome
Status: COMPLETED
Conditions: Carpal Tunnel Syndrome
Interventions: PROCEDURE: Platelet rich plasma|DEVICE: shock wave
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Utility of At-home Monitoring of Exercise Capacity by App-based 6-minute Walk Test
Status: ACTIVE_NOT_RECRUITING
Conditions: Pulmonary Arterial Hypertension
Interventions: DEVICE: Home-based 6 minute walk test
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparative Evaluation of Three Anxiety Control Protocols in Third Molar Extraction
Status: COMPLETED
Conditions: Anxiety Disease
Interventions: DRUG: Diazepam|DRUG: Midazolam|DRUG: Nitrous Oxide + Oxygen Gas|PROCEDURE: Third molar extraction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Application of Prophylactic Low Calorie Feeding in Critically Ill Patients With High-risk Refeeding Syndrome
Status: UNKNOWN
Conditions: Critical Illness
Interventions: DIETARY_SUPPLEMENT: standard enteral nutrition|DIETARY_SUPPLEMENT: restricted enteral nutrition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Ocular Comfort and the "Aging" Lens (ERBIUM)
Status: COMPLETED
Conditions: Refractive Error
Interventions: DEVICE: Habitual contact lens|DEVICE: Lotrafilcon B contact lens|DEVICE: Contact lens cleaning and disinfecting system (ClearCare)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cervical Cerclage for Preventing Spontaneous Preterm Birth in Singleton Pregnancies Without Prior Spontaneous Preterm Birth and With Short Transvaginal Ultrasound Cervical Length
Status: UNKNOWN
Conditions: Preterm Birth
Interventions: PROCEDURE: Cervical cerclage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neurofeedback to Improve Working Memory in Mild Cognitive Impairment
Status: RECRUITING
Conditions: Mild Cognitive Impairment
Interventions: BEHAVIORAL: Neurofeedback|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Safety Study of PTI-125 in Healthy Volunteers
Status: COMPLETED
Conditions: Alzheimer Disease, Early Onset|Alzheimer Disease
Interventions: DRUG: 50 mg PTI-125|DRUG: 100 mg PTI-125|DRUG: 200 mg PTI-125
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Drug-interaction Trial in Healthy Subjects With Oral Administration of Empagliflozin (BI 10773), Rifampicin and Probenecid
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Probenecid|DRUG: Rifampicin|DRUG: Empagliflozin|DRUG: Empagliflozin|DRUG: Rifampicin|DRUG: Probenecid|DRUG: Empagliflozin (BI 10773)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vorinostat and Gemcitabine in Treating Patients With Metastatic or Unresectable Solid Tumors
Status: COMPLETED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: vorinostat|DRUG: gemcitabine hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: OPTImal Management of Antithrombotic Agents: OPTIMA-2 Trial
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DRUG: Clopidogrel|DRUG: Cilostazol|DRUG: Ticagrelor|DRUG: Clopidogrel|DRUG: Clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral VT-464 in Patients With Castration-Resistant Prostate Cancer Previously Treated With Enzalutamide, Androgen Receptor Positive Triple-Negative Breast Cancer Patients, and Men With ER Positive Breast Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: VT-464: given orally twice daily in 28-day cycles|DRUG: VT-464: given orally once daily in 28-day cycles
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I/Ib Study of NZV930 Alone and in Combination With PDR001 and /or NIR178 in Patients With Advanced Malignancies.
Status: TERMINATED
Conditions: Non-small Cell Lung Cancer (NSCLC)|Triple Negative Breast Cancer (TNBC)|Pancreatic Ductal Adenocarcinoma (PDAC)|Colorectal Cancer Microsatellite Stable (MSS)|Ovarian Cancer|Renal Cell Carcinoma (RCC)|Metastatic Castration Resistant Prostate Cancer (mCRPC)
Interventions: OTHER: NZV930|OTHER: PDR001|DRUG: NIR178
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Deworming and Vitamin A (DEVTA) Prepilot Study
Status: COMPLETED
Conditions: Malnutrition|Worm Infestation|Under-Fives
Interventions: DRUG: Albendazole (400 mg) and/or Vitamin a
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Improved Orthostatic Tolerance = Better Cognitive Function in Parkinson's Disease
Status: COMPLETED
Conditions: Hypotension, Orthostatic|Parkinson Disease|Autonomic Failure|Cognitive Impairment
Interventions: OTHER: Physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: TCR-engineered T Cells in Solid Tumors: IMA202-101
Status: COMPLETED
Conditions: Solid Tumor, Adult|Refractory Cancer|Recurrent Cancer|Cancer
Interventions: DRUG: IMA202 Product|DEVICE: IMADetect®
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Induction Chemotherapy Followed by Cetuximab Plus Definitive Radiotherapy Versus Radiation Plus Cisplatin
Status: UNKNOWN
Conditions: Squamous Cell Carcinoma of the Head and Neck
Interventions: DRUG: docetaxel - cisplatin - 5-fluorouracil|RADIATION: radiotherapy|DRUG: cetuximab|DRUG: cisplatin|RADIATION: radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Benefit of Orthopedic Navigation in the ARThroplasty of the Hip
Status: COMPLETED
Conditions: Osteoarthritis, Hip|Arthritis, Rheumatoid|Femur Head Necrosis
Interventions: PROCEDURE: Manual Intervention|PROCEDURE: Navigated Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Increasing Naloxone Access for Persons Who Use Opioids
Status: COMPLETED
Conditions: Naloxone
Interventions: DRUG: Opioid Overdose Education with Naloxone Distribution|DRUG: Opioid Overdose Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Effects of Flaxseed Supplement on Biochemical Factors and Hepatic Fibrosis in Patients With Nonalcoholic Fatty Liver Disease
Status: COMPLETED
Conditions: Non Alcoholic Steatohepatitis
Interventions: DIETARY_SUPPLEMENT: Flaxseed|OTHER: control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study Comparing the Comfort of Three Commercially Available Contact Lenses
Status: WITHDRAWN
Conditions: Contact Lens Complication
Interventions: DEVICE: Acuvue® Oasys® Lenses (senofilcon A)|DEVICE: 30-Day Bausch + Lomb PureVision (balafilcon A)|DEVICE: Clariti® 1-Day (Somofilcon A)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: EXPAREL Infiltration in Subjects Undergoing Femoral Nerve Block With Bupivacaine HCl for Total Knee Arthroplasty
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Bupivacaine FNB|DRUG: EXPAREL Infiltration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improving Satisfaction, Engagement and Outcomes Among Traditionally Underserved Children Through Cultural Formulation
Status: COMPLETED
Conditions: Disruptive Behavior
Interventions: BEHAVIORAL: Clinical Assessment and CFI|BEHAVIORAL: Clinical Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Graphomotor Intervention Program for Handwriting Difficulties Prevention in School-Age
Status: COMPLETED
Conditions: Typical Development|Risk of Dysgraphia|Dysgraphia
Interventions: OTHER: Graphomotor intervention program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Comparison of White-light and Daylight Topical Methyl 5-aminolaevulinic Acid Photodynamic Therapy for Actinic Keratoses
Status: COMPLETED
Conditions: Actinic Keratoses
Interventions: DEVICE: Daylight and Maquet Power 500 LED surgery light
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Artificial Intelligence (IA) Advanced Triage Tool for G&O Emergencies
Status: ACTIVE_NOT_RECRUITING
Conditions: Emergencies
Interventions: DIAGNOSTIC_TEST: Advanced triage tool for Gynecology and Obstetrics emergencies based on artificial intelligence algorithms.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Use of Ixmyelocel-T (Formerly Vascular Repair Cells [VRC]) in Patients With Peripheral Arterial Disease to Treat Critical Limb Ischemia
Status: COMPLETED
Conditions: Peripheral Arterial Disease
Interventions: BIOLOGICAL: Ixmyelocel-T|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Histamine Human Immunoglobulin in the Treatment of Chronic Spontaneous Urticaria (CSU)
Status: NOT_YET_RECRUITING
Conditions: Chronic Spontaneous Urticaria
Interventions: BIOLOGICAL: human histaglobulin|BIOLOGICAL: placebo|DRUG: Loratadine 10 Mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness and Safety of Topical Finasteride and Minoxidil Combination Compared to Topical Minoxidil for The Treatment of Male Androgenetic Alopecia
Status: RECRUITING
Conditions: Androgenetic Alopecia
Interventions: DRUG: Finasteride|DRUG: Minoxidil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Integrated CBT to Improve Functioning in Veterans With Anxiety and Substance Use
Status: RECRUITING
Conditions: Anxiety Disorder|Posttraumatic Stress Disorder|Hazardous Drinking
Interventions: BEHAVIORAL: Unified Protocol- Alcohol|BEHAVIORAL: Problem Solving therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Daily Bitemporal Low-frequency Transcranial Random Noise Stimulation in Tinnitus (tRNS2-tin)
Status: RECRUITING
Conditions: Chronic Tinnitus
Interventions: DEVICE: lf-tRNS
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The JensClip Transcatheter Valve Repair System for Treating Functional Mitral Regurgitation
Status: ENROLLING_BY_INVITATION
Conditions: Functional Mitral Regurgitation
Interventions: DEVICE: moderate-severe or greater (MR ≥ 3+) functional mitral regurgitation (FMR) patients
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Optimal Antipsychotic Treatments for Adults With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Olanzapine|DRUG: Perphenazine|DRUG: Aripiprazole|DRUG: Metformin|DRUG: Simvastatin|DRUG: Benztropine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Bioavailability, Food Effect, Safety and Tolerability of a Solid Dosage Formulation of JNJ-54861911 in Healthy Older Male Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: JNJ-54861911 (Treatment A)|DRUG: JNJ-54861911 (Treatment B)|DRUG: JNJ-54861911 (Treatment C)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mass Balance of Orally Administered [14C] (3S,4S,5R)-1,3,4,5,6-pentahydroxy-hexan-2-one
Status: RECRUITING
Conditions: Energy Intake|Energy Metabolism
Interventions: OTHER: (3S,4S,5R)-1,3,4,5,6-pentahydroxy-hexan-2-one|COMBINATION_PRODUCT: 14C-(3S,4S,5R)-1,3,4,5,6-pentahydroxy-hexan-2-one
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Managing Asthma Patients With AMAZE™: A Novel Disease Management Platform
Status: COMPLETED
Conditions: Asthma
Interventions: DEVICE: AMAZE™ Application|DEVICE: AMAZE™ Dashboard
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: An RCT of an Online Training for Vulnerable Patients to Use an Online Patient Portal Website
Status: COMPLETED
Conditions: Electronic Health Records|Chronic Disease|Health Literacy
Interventions: BEHAVIORAL: Take-home online training|BEHAVIORAL: In-person online training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Suppressive Therapy With Oral Antibiotics for Prevention of Postoperative Urinary Tract Infection (UTI)
Status: COMPLETED
Conditions: Urinary Tract Infection
Interventions: DRUG: Nitrofurantoin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Niraparib In Recurrent IDH 1/2 Gliomas
Status: RECRUITING
Conditions: Low-grade Glioma|IDH2 Gene Mutation|Recurrent Glioma|IDH1 Mutation|Glioma, Malignant
Interventions: DRUG: Niraparib|DRUG: Resection/Treatment with Niraparib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Follow-up Evaluating Clinical and Radiological Outcomes of Total Shoulder Arthroplasty With Permedica's MIRAI Prosthesis
Status: ACTIVE_NOT_RECRUITING
Conditions: Cuff Tear Arthropathy|Primary Osteoarthritis|Secondary Osteoarthritis|Shoulder Osteoarthritis|Rheumatoid Arthritis Shoulder|Psoriatic Arthritis|Fracture, Shoulder|Avascular Necrosis of Humerus
Interventions: PROCEDURE: Total Shoulder Arthroplasty with Permedica's MIRAI
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Feasibility Study of the CELLSPAN Esophageal Implant (CEI) in Patients Requiring Short Segment Esophageal Replacement
Status: RECRUITING
Conditions: Esophageal Diseases
Interventions: COMBINATION_PRODUCT: Cellspan™ Esophageal Implant-Adult (CEI)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy in Treating Patients With Newly Diagnosed Acute or Chronic Myelogenous Leukemia or Myelodysplastic Syndrome
Status: COMPLETED
Conditions: Leukemia|Myelodysplastic Syndromes|Neutropenia
Interventions: BIOLOGICAL: filgrastim|BIOLOGICAL: lintuzumab|DRUG: cytarabine|DRUG: etoposide|DRUG: idarubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Identification of Biomarkers for the Study of the Diabetic Foot and Evolution.
Status: NOT_YET_RECRUITING
Conditions: Diabetes Mellitus|Diabetic Foot|Sarcopenia|Neuropathy, Diabetic|Vascular Disease, Peripheral|Metabolic Syndrome
Interventions: DIAGNOSTIC_TEST: BIOIMPEDANCEMETRY
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Neuroscience-Informed Treatment Development for Adolescent Alcohol Use
Status: COMPLETED
Conditions: Alcohol Drinking|Control
Interventions: DRUG: N-Acetylcysteine|DRUG: Placebo Oral Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Biosynthesis of PGD2 in Vivo
Status: COMPLETED
Conditions: Hyperlipidemia
Interventions: DRUG: Aspirin|DRUG: Placebo|DRUG: Niacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Brimonidine Purite 0.15% Versus Dorzolamide 2% Used as Adjunctive Therapy to Latanoprost
Status: COMPLETED
Conditions: Glaucoma
Interventions: DRUG: Brimonidine Purite 0.15%, Dorzolamide 2%, Latanoprost
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose:
Clinical trial: Prostate Reirradiation Toxicity Outcomes Feasibility Study
Status: NOT_YET_RECRUITING
Conditions: Prostate Cancer|Radiotherapy Side Effect
Interventions: RADIATION: Brachytherapy|RADIATION: Sterotactic Body Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Understanding the Predictive Factors and the Neurocognitive Basis of Developmental Language Disorder
Status: UNKNOWN
Conditions: Developmental Language Disorders|Language Development
Interventions: BEHAVIORAL: Risk profile screening questionnaire|PROCEDURE: Investigation of the neural correlates of DLD using Magnetic Resonance Imagery (MRI)|BEHAVIORAL: Online investigation of predictive factors associated with DLD and LANCOM app development|BEHAVIORAL: Individual behavioral and cognitive assessment|BEHAVIORAL: Automated analysis of language development and environment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect of the COVID-19 Pandemic on Frailty in Liver Transplant Candidates
Status: ACTIVE_NOT_RECRUITING
Conditions: Frailty|Sarcopenia|COVID-19
Interventions: BEHAVIORAL: COVID Patients who Underwent pre-transplant frailty assessment (PFA) at MDMC
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Drug Interaction Study of VI-0521 With Metformin, Sitagliptan and Probenecid in Healthy Subjects.
Status: COMPLETED
Conditions: Obesity
Interventions: DRUG: Metformin, VI-0521, Sitagliptan, Probenecid
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Spinal Segment MRI Perfusion and Diffusion Response to Spinal Manipulation in Low Back Pain Patients
Status: RECRUITING
Conditions: Pain, Back
Interventions: OTHER: Spinal Manipulative Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CEOP/IVE/GDP Compared With CEOP as the First-line Therapy for Newly Diagnosed Adult Patients With PTCL
Status: UNKNOWN
Conditions: Peripheral T-Cell Lymphoma, Not Otherwise Specified|Angioimmunoblastic T Cell Lymphoma|ALK-negative Anaplastic Large Cell Lymphoma|Enteropathy Associated T Cell Lymphoma|Subcutaneous Panniculitis Like T Cell Lymphoma|Hepatosplenic T-cell Lymphoma
Interventions: DRUG: CEOP/IVE/GDP chemotherapy regimen|DRUG: CEOP chemotherapy regimen for 6 cycles
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TC or BEP in Treating Patients With Ovarian Malignant Sex Cord-Stromal Tumors
Status: RECRUITING
Conditions: Ovarian Sex Cord Stromal Tumor|Ovarian Neoplasms|Ovarian Cancer
Interventions: DRUG: Paclitaxel|DRUG: Carboplatin|DRUG: Bleomycin|DRUG: Etoposide|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Insulin Glargine in Type 2 Diabetic Patients
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Insulin Glargine|DRUG: Glyburide|DRUG: Glyclazide|DRUG: Glimiperide|DRUG: Glipizide|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical and Microbiologic Outcomes of Adjunctive Antimicrobial Photodynamic Therapy in the Non-surgical and Surgical Treatment of Teeth With Periodontal Disease
Status: RECRUITING
Conditions: Periodontal Diseases
Interventions: DEVICE: mechanical debridement|DEVICE: adjunctive aPDT|DEVICE: sham aPDT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Vinorelbine Metronomic Plus Bevacizumab as Salvage Therapy for Breast Cancer
Status: TERMINATED
Conditions: Breast Cancer
Interventions: DRUG: Vinorelbine|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Leukocyte-rich PRP vs Leukocyte-poor PRP for the Treatment of Knee Cartilage Degeneration: a Randomized Controlled Trial
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: BIOLOGICAL: Leukocyte-rich PRP intra-articular injections|BIOLOGICAL: Leukocyte-poor PRP intra-articular injections
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Taurine Supplementation and Training Effects on Energy Metabolism, Inflammation and Oxidative Stress in Obese Women
Status: COMPLETED
Conditions: Obesity
Interventions: DIETARY_SUPPLEMENT: Taurine|DIETARY_SUPPLEMENT: Placebo|OTHER: Exercise training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Efficacy and Safety of Filgotinib in Participants With Active Ankylosing Spondylitis Who Are Naive to Biologic Disease-Modifying Antirheumatic Drug Therapy
Status: WITHDRAWN
Conditions: Ankylosing Spondylitis
Interventions: DRUG: Filgotinib|DRUG: Placebo to Match Filgotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Double Guidewire Technique Versus Transpancreatic Precut in Patients With Repetitive Unintentional Cannulation of the Pancreatic Duct.
Status: UNKNOWN
Conditions: Endoscopic Retrograde Cholangiopancreatography|Common Bile Duct Diseases|Transpancreatic Precut|Precut|Double Guidewire
Interventions: PROCEDURE: Double guidewire|PROCEDURE: Transpancreatic precut
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Stereotactic Radiotherapy Combined With Adebrelimab and TCb (Nab-paclitaxel + Carboplatin) in Neoadjuvant Treatment of TNBC
Status: RECRUITING
Conditions: Stereotactic Radiotherapy|Immunotherapy|Breast Cancer
Interventions: DRUG: adebrelimab plus stereotactic radiotherapy followed by adebrelimab plus chemotherapy (nab-paclitaxel + carboplatin)|DRUG: adebrelimab plus chemotherapy (nab-paclitaxel + carboplatin)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dexamethasone, Flurbiprofen Axetil and Delirium After Lung Cancer Surgery
Status: TERMINATED
Conditions: Carcinoma, Non-Small-Cell Lung|Surgery--Complications|Dexamethasone|Flubiprofen Axetil|Delirium
Interventions: DRUG: Dexamethasone|DRUG: Normal saline|DRUG: Flurbiprofen axetil|DRUG: Lipid microsphere
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Dose Escalation of Hypofractionated Radiation Therapy in Patients With Metastatic Cancer
Status: COMPLETED
Conditions: Tumor|Cancer|Melanoma|Sarcoma|Carcinoma
Interventions: RADIATION: Hypofractionated RT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Vitamin C on Biomarkers of Neurologic Injury in Survivors of Cardiac Arrest
Status: UNKNOWN
Conditions: Heart Arrest, Out-Of-Hospital|Biomarkers|Oxidative Stress|Neurological Injury
Interventions: DRUG: Vitamin C|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Apnea, Stroke and Incident Cardiovascular Events
Status: RECRUITING
Conditions: Stroke|Sleep-disordered Breathing|Sleep Apnea Syndromes|Sleep Apnea, Obstructive|Sleep Apnea, Central|Fragmentation, Sleep
Interventions: DEVICE: Treatment according to standard care recommandation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Zambia Integrated Management of Malaria and Pneumonia Study
Status: COMPLETED
Conditions: Pneumonia|Malaria
Interventions: DRUG: Coartem and amoxicillin|DRUG: Coartem
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Acceptability and Feasibility of Injectable Cabotegravir Pre-exposure Prophylaxis (PrEP) Versus Oral PrEP in Routine Care up to 15 Months in Private Pharmacies in South Africa
Status: ACTIVE_NOT_RECRUITING
Conditions: HIV Infections
Interventions: DRUG: Cabotegravir Injection [Apretude]|DRUG: Tenofovir disoproxil fumarate / emtricitabine (or lamivudine)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Convalescent Plasma to Stem Coronavirus (CSSC-001)
Status: COMPLETED
Conditions: Coronavirus|Convalescence
Interventions: BIOLOGICAL: Anti- SARS-CoV-2 Plasma|BIOLOGICAL: SARS-CoV-2 non-immune Plasma
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: EMPA Acute Heart Failure
Status: TERMINATED
Conditions: Diabetes Mellitus, Type 2|Acute Heart Failure
Interventions: DRUG: Empagliflozin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Tolerability of Rimegepant for the Acute Treatment of Migraine in Adults Unsuitable for Triptan Use
Status: RECRUITING
Conditions: Migraine
Interventions: DRUG: Rimegepant|DRUG: Placebo|DRUG: Rimegepant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Twice Weekly TP-HDFL for Recurrent or Metastatic Esophageal Cancer
Status: COMPLETED
Conditions: Esophageal Cancer
Interventions: DRUG: Paclitaxel,Cisplatin,5-Fu,Folic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Can Protein Intake be Increased Using Whole Foods Post-treatment in Cancer Patients?
Status: RECRUITING
Conditions: Cancer|Other Malnutrition
Interventions: OTHER: ≥ 2 eggs in addition to usual diet for 8 weeks|OTHER: ≥ 2 eggs in addition to usual diet for 4 weeks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of 2 Extracts of Saw Palmetto Versus Placebo on Lower Urinary Tract Symptoms (LUTS) and Urinary Frequency
Status: NOT_YET_RECRUITING
Conditions: Lower Urinary Tract Symptoms
Interventions: DRUG: Saw palmetto extract 320mg per day|DRUG: Commercial Saw palmetto extract 320mg per day|DRUG: Palm Oil capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized Study of Iodine-131 Anti-b1 Antibody Versus Anti-b1 Antibody in Chemotherapy-relapsed/Refractory Low-grade or Transformed Low-grade Non-Hodgkin's Lymphoma (NHL)
Status: COMPLETED
Conditions: Lymphoma, Non-Hodgkin
Interventions: BIOLOGICAL: Iodine-131 Anti-B1 Antibody Versus Anti-B1 Antibody in Chemotherapy-Relapsed/Refractory Low-Grade or Transformed Low-Grade Non-Hodgkin's Lymphoma (NHL)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: NIV Strategies for RDS in Preterm Infants. NIV (Non Invasive Ventilation), RDS (Respiratory Distress Syndrome)
Status: COMPLETED
Conditions: RDS of Prematurity
Interventions: DEVICE: NSIPPV|DEVICE: BiPAP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Clinical Trial of Vitamin E and Evening Oil of Primrose for the Managment of Breast Pain
Status: COMPLETED
Conditions: Cyclical Breast Pain
Interventions: DRUG: Vitamin E, Evening Oil of Primrose, and Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Osteotome-mediated Sinus Floor Elevation With or Without Grafting Material
Status: COMPLETED
Conditions: Survival, Prosthesis|Bone Loss|Patient Satisfaction
Interventions: PROCEDURE: Sinus floor elevation with a grafting material
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: CT-angiographic Follow up of Patients That Underwent Coronary Bypass Surgery Between 1993-1997
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: PROCEDURE: No touch technique|PROCEDURE: Conventional technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects Of HMO On The Faecal Microbiota And On Gastrointestinal Symptoms In Healthy Volunteers
Status: COMPLETED
Conditions: Gut Microbiota|Gastrointestinal Symptoms
Interventions: DIETARY_SUPPLEMENT: HMO|DIETARY_SUPPLEMENT: Glucose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Diabetic Foot Ulcer Study on Topical Interventions
Status: COMPLETED
Conditions: Diabetic Foot
Interventions: DEVICE: Acticoat absorbent|DEVICE: Honey gel sheet|DEVICE: Jelonet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: First Human Dose Trial of NNC0195-0092 (Somapacitan) in Healthy Subjects
Status: COMPLETED
Conditions: Growth Hormone Disorder|Adult Growth Hormone Deficiency|Growth Hormone Deficiency in Children|Healthy
Interventions: DRUG: somapacitan|DRUG: placebo (somapacitan)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Outpatient Health Care Program for Older Patients Receiving Chemotherapy for Newly Diagnosed Breast Cancer or Colon Cancer
Status: WITHDRAWN
Conditions: Breast Cancer|Cognitive/Functional Effects|Colorectal Cancer|Psychosocial Effects of Cancer and Its Treatment
Interventions: DRUG: chemotherapy|OTHER: medical chart review|OTHER: questionnaire administration|PROCEDURE: adjuvant therapy|PROCEDURE: assessment of therapy complications|PROCEDURE: cognitive assessment|PROCEDURE: psychosocial assessment and care|PROCEDURE: quality-of-life assessment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Macular Micro Vascular Changes Following Macular Hole Repair : Optical Coherence Tomography Angiography Study
Status: RECRUITING
Conditions: Macular Holes
Interventions: PROCEDURE: pars plana vitrectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study of the Human Anti-TNF Monoclonal Antibody Adalimumab for the Induction of Clinical Remission in Subjects With Crohn's Disease
Status: COMPLETED
Conditions: Crohn's Disease
Interventions: DRUG: Adalimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Implementation of a Best Practice Primary Health Care Model for Low Back Pain
Status: COMPLETED
Conditions: Low Back Pain
Interventions: BEHAVIORAL: Current routine practice|BEHAVIORAL: Multifaceted implementation of the BetterBack
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Repetitive Transcranial Magnetic Stimulation in Amphetamine Addiction
Status: COMPLETED
Conditions: Craving|Depression, Anxiety|Amphetamine Addiction
Interventions: DEVICE: transcranial magnetic stimulation (TMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gluten-related Disorders in Familial Mediterranean Fever Patients
Status: COMPLETED
Conditions: Not-celiac Wheat Sensitivity (NCWS)|Familial Mediterranean Fever (FMF)
Interventions: OTHER: Wheat flour|OTHER: Placebo Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Nimotuzumab in Combined With Paclitaxel and Cisplatin for Treatment of Metastatic Esophageal Squamous Cell Carcinoma
Status: UNKNOWN
Conditions: Esophageal Squamous Cell Carcinomas
Interventions: DRUG: Nimotuzumab|DRUG: Paclitaxel|DRUG: Cisplatin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Relationship Between Trunk Position Sense and Muscle Activation, Balance and Quality of Life in Amputees
Status: NOT_YET_RECRUITING
Conditions: Amputation|Muscle Activation|Balance|Quality of Life|Sense of Control
Interventions: DIAGNOSTIC_TEST: Investigation of the relationship between trunk position sense and muscle activation, balance and quality of life in individuals with transtibial amputation.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study to Evaluate if the Addition of r-hLH (Luveris®) to FSH From Day 8 of Ovarian Stimulation is Able to Decrease Total FSH Dose and to Improve Cycle Outcome in Infertile Women Undergoing ART, Who Required High FSH Dose in a Previous Cycle
Status: TERMINATED
Conditions: Reproductive Techniques, Assisted
Interventions: DRUG: Recombinant human Follicle Stimulating Hormone (r-hFSH) and Recombinant human Luteinizing Hormone (r-hLH)|DRUG: r-hFSH
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of the Nasal Provocation on the Breathing Style
Status: UNKNOWN
Conditions: Birch Pollen Allergy|Healthy Control Subjects
Interventions: BIOLOGICAL: 1. session birch pollen nasal exposure 2. session xylometazoline nasal exposure
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficiency of Using Copper-Nickel-Titanium Versus Nickel-Titanium Arch Wires on Anterior Segment Crowding Alleviation in Group of Adults With Moderate Crowding
Status: UNKNOWN
Conditions: Crowding of Anterior Mandibular Teeth
Interventions: DEVICE: Copper Nickel titanium arch wire
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Oral LPCN 1021 in Men With Low Testosterone or Hypogonadism
Status: COMPLETED
Conditions: Male Hypogonadism
Interventions: DRUG: Oral testosterone undecanoate, LPCN 1021|DRUG: Topical testosterone gel 1.62 %
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An RCT to Compare Early Continence Recovery After RARP With or Without Sustainable Functional Urethral Reconstruction
Status: COMPLETED
Conditions: Prostate Cancer|Urinary Incontinence
Interventions: PROCEDURE: SFUR-RARP|PROCEDURE: Standard RARP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pelvic Floor Muscle Training and Kaatsu Training for Women With Stress Urinary Incontinence
Status: COMPLETED
Conditions: Urinary Stress Incontinence
Interventions: BEHAVIORAL: Pelvic floor muscle training and Kaatsu|BEHAVIORAL: Pelvic floor muscle training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Second-Line Irinotecan or Gefitinib in Docetaxel Pretreated NSCLC
Status: UNKNOWN
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: Gefitinib|DRUG: Irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT