pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Study To Access The Safety And Tolerability Of RN316 (PF-04950615) When Administered To Healthy Adult Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: BIOLOGICAL: RN316
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Long-Term Follow-up Study of Subjects Treated With Autologous T Cells Using the Sleeping Beauty System to Express TCRs
Status: ACTIVE_NOT_RECRUITING
Conditions: Gynecologic Cancer|Colorectal Cancer|Pancreatic Cancer|Non-small Cell Lung Cancer|Cholangiocarcinoma|Ovarian Cancer|Ovary Neoplasm|Squamous Cell Lung Cancer|Adenocarcinoma of Lung|Adenosquamous Cell Lung Cancer
Interventions: BIOLOGICAL: Neoantigen specific TCR-T cell drug product
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Periodontal and Cardiovascular Diseases Project
Status: TERMINATED
Conditions: Periodontitis|Cardiovascular Diseases
Interventions: PROCEDURE: Scaling and root planing|PROCEDURE: Supragingival prophylaxis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PROspective Trial on EOsinophilia in Non-Small Cell Lung Cancer (NSCLC).
Status: RECRUITING
Conditions: Non-small Cell Lung Cancer
Interventions: DIAGNOSTIC_TEST: induced sputum|DIAGNOSTIC_TEST: lung biopsy|DIAGNOSTIC_TEST: bronchoalveolar lavage|DIAGNOSTIC_TEST: blood draw
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Pre-emptive Treatments in Lupus Nephritis Patients With Serological Reactivation
Status: UNKNOWN
Conditions: Lupus Nephritis
Interventions: PROCEDURE: Pre-emptive increase of immunosuppressive treatments|DRUG: Prednisolone and/or AZA/MMF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sedation in Patients Undergoing GIT Endoscopy
Status: NOT_YET_RECRUITING
Conditions: Sedation for Patients Undergoing GIT Endoscopy
Interventions: DRUG: propofol and magnesium sulphate ,propofol and nalbuphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Development and Efficacy Test of Computerized Treatment for Marijuana Dependence
Status: COMPLETED
Conditions: Marijuana Abuse and Dependence
Interventions: BEHAVIORAL: Psychotherapy|BEHAVIORAL: Computerized Psychotherapy|BEHAVIORAL: Motivational enhancement therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dual-targeting HER2 and PD-L1 CAR-T for Cancers With Pleural or Peritoneal Metastasis
Status: RECRUITING
Conditions: Peritoneal Carcinoma Metastatic|Pleural Effusion, Malignant
Interventions: BIOLOGICAL: Dual-targeting HER2 and PD-L1 CAR-T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Genetic Overlap Between Anomalies and Cancer in Kids in the Children's Oncology Group: The COG GOBACK Study
Status: RECRUITING
Conditions: Congenital Anomaly|Pediatric Cancer
Interventions: OTHER: Whole Genome Sequencing|OTHER: Questionnaire Administration|OTHER: Biospecimen collection|OTHER: Laboratory Biomarker Analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Exercise Prehabilitation for Patients With NSCLC Before Surgery
Status: RECRUITING
Conditions: Prehabilitation|Non Small Cell Lung Cancer|Cardiorespiratory Fitness|Surgery
Interventions: BEHAVIORAL: Multimodal prehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Ataluren in Participants With Nonsense Mutation Aniridia
Status: COMPLETED
Conditions: Aniridia
Interventions: DRUG: Ataluren|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fasted Pharmacokinetic and Bioequivalency Study of Fenofibric Acid
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Fenofibric Acid 35 mg Tablet|DRUG: Fenofibric Acid 35 mg Tablet|DRUG: Fenofibric Acid 105 mg Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy of a Minimal Intervention Educational Program in the Asthma Control and Exacerbations Prevention
Status: COMPLETED
Conditions: Asthma
Interventions: OTHER: Clinical practice group|OTHER: "Gold Standard" educational group|OTHER: Intervention group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Enhancing Recovery in Non-Traumatic Spinal Cord Injury
Status: RECRUITING
Conditions: Spinal Cord Compression|Spinal Cord Injuries|Cervical Spondylosis|Myelopathy Cervical
Interventions: BEHAVIORAL: Occupational therapy rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I/II Trial of Cord Blood-Derived NK Cells Genetically Engineered With NY-ESO-1 TCR/IL-15 Cell Receptor for Relapsed/Refractory Multiple Myeloma
Status: RECRUITING
Conditions: Myeloma
Interventions: DRUG: Fludarabine phosphate|DRUG: Cyclophosphamide|DRUG: NY-ESO-1 TCR/IL-15 NK
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improving Diabetes in Emerging Adulthood
Status: RECRUITING
Conditions: Diabetes Mellitus, Type 1
Interventions: BEHAVIORAL: Motivational Enhancement System (MES)|BEHAVIORAL: Question Prompt List (QPL)|BEHAVIORAL: Text Message Reminders (TXT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lutonix® Global AV Registry Investigating Lutonix Drug Coated Balloon for Treatment of Native and Synthetic AV Fistulae
Status: COMPLETED
Conditions: Arteriovenous Fistula
Interventions: DEVICE: Lutonix 035 Drug Coated Balloon PTA Catheter, Model 9004
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Spinal Stimulation and Mobility Devices
Status: RECRUITING
Conditions: Cerebral Palsy|Stroke|Premature Birth|Hypoxic-Ischemic Encephalopathy|Periventricular Leukomalacia
Interventions: DEVICE: Mobility Device|DEVICE: Spinal Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Medial Retinacular Plication Versus Medial Patellofemoral Ligament Reconstruction for Recurrent Patellar Instability
Status: UNKNOWN
Conditions: Patella, Familial Recurrent Dislocation Of
Interventions: PROCEDURE: Surgical treatment for recurrent patellar instability
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acute Effects of Juice Consumption With Biofunctional Compounds and Probiotics on Glucose Metabolism
Status: COMPLETED
Conditions: Potential Abnormality of Glucose Tolerance|Appetite Disorders
Interventions: OTHER: Glucose as reference food|OTHER: Control juice|OTHER: Juice with vitamin D3|OTHER: Juice with n-3 fatty acids|OTHER: Juice with probiotics|OTHER: Juice with probiotics, vitamin D3, and n-3 fatty acids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: A One Year Clinical Trial Assessing the Usefulness and Safety of Inhaled Insulin in Diabetics With Asthma
Status: COMPLETED
Conditions: Asthma|Diabetes Mellitus
Interventions: DRUG: Inhaled Insulin|DRUG: Subcutaneous Insulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Of The Treatment Effects Of Different Methods In Patients With Calcaneal Spur
Status: COMPLETED
Conditions: Heel Spur
Interventions: OTHER: Extracorporeal shock wave therapy|OTHER: Kinesiology taping|OTHER: Extracorporeal shock wave therapy+Kinesiology taping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: To Evaluate the Safety and Pharmacokinetic Characteristics After Multiple Administration of JC-013 and JLP-2004
Status: COMPLETED
Conditions: Healthy Adult
Interventions: DRUG: JLP-2004|DRUG: JC-013
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparison Between STN-DBS and GPi-DBS in Meige Syndrome Evaluated by Flexible Electrodes
Status: RECRUITING
Conditions: Meige Syndrome
Interventions: DEVICE: Bilateral STN deep brain stimulation|DEVICE: Bilateral GPi deep brain stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of New Mometasone Furoate Nasal Spray Formulation in Acute Rhinosinusitis Patients: A Randomized Clinical Trial
Status: COMPLETED
Conditions: Acute Rhinosinusitis
Interventions: DRUG: Mometasone Nasal 50 Mcg/Inh Nasal Spray|DEVICE: Nasal spray
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Role of Cetrotide Acetate in Prevention of Ovarian Hyperstimulation Syndrome (OHSS) in Oocyte Donors
Status: COMPLETED
Conditions: Ovarian Hyperstimulation Syndrome
Interventions: DRUG: Cetrotide acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Chemotherapy, Radiation Therapy, Rituximab, and Umbilical Cord Blood Transplant in Treating Patients With B-Cell Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Leukemia|Lymphoma
Interventions: BIOLOGICAL: filgrastim|BIOLOGICAL: rituximab|DRUG: cyclophosphamide|DRUG: cyclosporine|DRUG: fludarabine phosphate|DRUG: mycophenolate mofetil|PROCEDURE: allogeneic hematopoietic stem cell transplantation|PROCEDURE: umbilical cord blood transplantation|RADIATION: total-body irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tenecteplase Reperfusion Therapy in Acute Ischemic Cerebrovascular Events(TRACE)
Status: COMPLETED
Conditions: Acute Ischemic Stroke
Interventions: DRUG: TNK-tPA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Telehealth Monitoring in Chronic Obstructive Pulmonary Disease
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DEVICE: Telehealth monitoring system (Honni Med)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Comparison of Two Brief Interventions for People With Chronic Low Back Pain
Status: RECRUITING
Conditions: Low Back Pain
Interventions: OTHER: Oldpain2go®|OTHER: Jacobson's progressive relaxation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety of AB-1003 (Previously LION-101) in Subjects With Genetic Confirmation of LGMD2I/R9 (Part1)
Status: RECRUITING
Conditions: Limb Girdle Muscular Dystrophy|Limb-Girdle Muscular Dystrophy Type 2|LGMD2I|Muscular Dystrophy|LGMD2|LGMD|FKRP|FKRP Mutation|Fukutin Related Protein
Interventions: GENETIC: AB-1003 dose level 1|GENETIC: AB-1003 dose level 2|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized, Double-blind, Placebo-controlled, Sequential Ascending, Single-dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of E2212 in Healthy Subjects
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: E2212|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Physician Awareness of Patients' Preferred Level of Involvement in Decision Making
Status: COMPLETED
Conditions: Preferred Level of Involvement in Decision Making
Interventions: OTHER: Physician Awareness|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Evaluation of the Neuroinflammation Pattern of BAY85-8102 F-18, DPA-714 in Probable Alzheimers Disease Patients Versus Healthy Volunteers and Radiation Dosimetry of F 18, DPA-714 in Healthy Volunteers
Status: COMPLETED
Conditions: Diagnostic Imaging
Interventions: DRUG: F-18 DPA-714 (BAY85-8102)|DRUG: F-18 DPA-714 (BAY85-8102)|DRUG: F-18 DPA-714 (BAY85-8102)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of RO4917838 (Bitopertin) in Patients With Sub-optimally Controlled Symptoms of Schizophrenia (WN25305)
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Placebo|DRUG: bitopertin [RO4917838] level 1|DRUG: bitopertin [RO4917838] level 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: To Compare the Pharmacokinetics and Safety of PBP1502 and Humira in Healthy Subjects
Status: RECRUITING
Conditions: Healthy Volunteers
Interventions: DRUG: PBP1502|DRUG: EU-licensed Humira|DRUG: US-licensed Humira
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Malt-derived Ingredients and Their Prolactinotrophic Effects
Status: COMPLETED
Conditions: Acute Response to Food Ingredient Consumption
Interventions: DIETARY_SUPPLEMENT: Malt ingredient|DIETARY_SUPPLEMENT: Non-alcoholic beer solids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Optimising Radiation Therapy in Head and Neck Cancers Using Functional Image-Guided Radiotherapy and Novel Biomarkers
Status: UNKNOWN
Conditions: Head and Neck Cancer
Interventions: RADIATION: Adaptive Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Thora-3DI™ for Evaluation of Severity of Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DEVICE: Thora-3Di|DEVICE: Body Plethysmography|DEVICE: Spirometry
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: A Trial of TD0019 in Treatment of Cervical Scapulohumeral Syndrome
Status: COMPLETED
Conditions: Syndrome Pain
Interventions: DRUG: TD0019 oral capsule|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Dose of Buglossoides Oil on EPA Accrual and on the Inflammatory Response
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Buglossoides oil|DIETARY_SUPPLEMENT: High Oleic Sunflower Oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Meditation Utilizing Signals From Electroencephalography in Chronic Pain (MUSE-PAIN) Study
Status: COMPLETED
Conditions: Chronic Pain
Interventions: DEVICE: Muse-S headband; InteraXon Inc., RRID:SCR_014418
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Study of Mechanism of Alzheimer's Disease Using Acupuncture Based on fMRI
Status: UNKNOWN
Conditions: Alzheimer's Disease
Interventions: PROCEDURE: true acupuncture|PROCEDURE: sham acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Enhancement of Hippocampal Plasticity Using Repetitive Transcranial Magnetic Stimulation
Status: RECRUITING
Conditions: Mild Cognitive Impairment
Interventions: DEVICE: TBS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Non-invasive Intermittent Theta Burst Stimulation of the Dorsolateral Prefrontal Cortex in Functional Movement Disorders
Status: RECRUITING
Conditions: Functional Movement Disorder
Interventions: DEVICE: MagStim|OTHER: Sham Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Yuxuebi Tablet in Treating Night Pain of Ankylosing Spondylitis (AS).
Status: UNKNOWN
Conditions: Ankylosing Spondylitis
Interventions: DRUG: Yuxuebi tablet|DRUG: Placebo tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Beta-glucan on Fecal Microflora in Polypectomized Patients
Status: COMPLETED
Conditions: Polypectomized Patients
Interventions: DIETARY_SUPPLEMENT: wheat bread with beta-glucan|DIETARY_SUPPLEMENT: wheat bread without beta-glucan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Anti-inflammatory and Anti-microbial Co-supplementations in Traumatic ICU Patients at High Risk of Sepsis
Status: COMPLETED
Conditions: Major Trauma|Sepsis
Interventions: DRUG: oral lactobacillus probiotics plus intramuscular cholecalciferol|DRUG: intravenous vitamin C plus thiamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Adjunctive Therapy of Exenatide or Sitagliptin to Insulin Glargine in Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: insulin glargine + exenatide + preexisting metformin|DRUG: insulin glargine + sitagliptin + preexisting metformin|DRUG: insulin glargine + preexisting metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: X-82 to Treat Age-related Macular Degeneration
Status: TERMINATED
Conditions: Age-Related Macular Degeneration (AMD)|Macular Degeneration|Exudative Age-related Macular Degeneration|AMD|Macular Degeneration, Age-related, 10|Eye Diseases|Retinal Degeneration|Retinal Diseases
Interventions: DRUG: X-82|DRUG: Anti-VEGF|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Telehealth Mindfulness-Based Music and Songwriting for Parents of Children With Intellectual/Developmental Disabilities
Status: COMPLETED
Conditions: Parents|Stress|Developmental Disability|Intellectual Disability|Autism Spectrum Disorder
Interventions: BEHAVIORAL: Mindfulness-Based Music and Songwriting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Effectiveness of Asoprisnil in the Treatment of Uterine Fibroids
Status: COMPLETED
Conditions: Leiomyoma
Interventions: DRUG: Asoprisnil|DRUG: Asoprisnil|DRUG: Asoprisnil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dovitinib for Imatinib/Sumitinib-failed Gastrointestinal Stromal Tumors (GIST): TKI258
Status: COMPLETED
Conditions: Gastrointestinal Stromal Tumors
Interventions: DRUG: dovitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effectiveness and Implementation of the BETTER Women Peer Health Coaching Program
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Disease|Cancer
Interventions: OTHER: Prevention Visit|BEHAVIORAL: Peer health coaching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Efficacy and Safety of DLBS3233 in Subjects With Polycystic Ovary Syndrome (PCOS)
Status: COMPLETED
Conditions: Polycystic Ovary Syndrome (PCOS)
Interventions: DRUG: DLBS3233|DRUG: Metformin XR|DRUG: Placebo caplet of Metformin XR|DRUG: Placebo capsule of DLBS3233
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ET1402L1-ARTEMIS™2 T Cells in Alpha Fetoprotein (AFP) Expressing Hepatocellular Carcinoma
Status: COMPLETED
Conditions: Hepatocellular Carcinoma|Liver Cancer|Liver Neoplasms|Metastatic Liver Cancer
Interventions: BIOLOGICAL: ET1402L1-ARTEMIS™ T cells -IV|BIOLOGICAL: ET1402L1-ARTEMIS™ T cells -intra-hepatic artery|BIOLOGICAL: ET1402L1-ARTEMIS™ T cells -Intratumoral Injections
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Use of Magnesium to Improve Blood Pressure, Cholesterol, and Glucose Control
Status: COMPLETED
Conditions: Coronary Artery Disease|Hypertension|Dyslipidemia|Diabetes
Interventions: DRUG: magnesium L-lactate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Drug-Drug Interaction Study in Healthy Subjects
Status: COMPLETED
Conditions: Hepatitis C
Interventions: DRUG: BMS-650032|DRUG: BMS-790052|DRUG: BMS-650032|DRUG: BMS-790052
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: VA Combined With PD-1 Inhibitor for the Treatment of Relapsed and Refractory AML and High-risk MDS
Status: RECRUITING
Conditions: Relapsed Acute Myeloid Leukemia|Refractory Acute Myeloid Leukemia|Myelodysplastic Syndromes|Minimal Residual Disease
Interventions: DRUG: PD-1 inhibitor, Venetoclax, Decitabine, Azacytidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Safety and Activity of TRL1068 in Prosthetic Joint Infections
Status: COMPLETED
Conditions: Prosthetic Joint Infection
Interventions: DRUG: TRL1068, a human monoclonal antibody
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Behavioral Interventions to Reduce Heavy Drinking Among MSM in HIV Primary Care
Status: COMPLETED
Conditions: Alcohol Drinking|HIV
Interventions: BEHAVIORAL: Motivational intervention|BEHAVIORAL: Brief Advice|BEHAVIORAL: Interactive text messaging
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Long Term Prevention of Nausea and Vomiting in Gynecologic Laparoscopy
Status: UNKNOWN
Conditions: Uterine Myoma, Ovary Neoplasm, Adenomyosis
Interventions: DRUG: Ramosetron
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Nilotinib Pre and Post Allogeneic Stem Cell Transplantation
Status: COMPLETED
Conditions: Chronic Myeloid Leukemia|Acute Lymphoblastic Leukemia|Stem Cell Transplantation
Interventions: DRUG: Nilotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy and Radiation in Treating Participants With Stage 3 Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: Pemetrexed|DRUG: Cisplatin|DRUG: Etoposide|DRUG: Vinorelbine|DRUG: Paclitaxel|DRUG: Carboplatin|RADIATION: Thoracic Radiation Therapy (TRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study on the Peristaltic Direction of GI Anastomosis in Roux-en-Y Reconstruction
Status: UNKNOWN
Conditions: Peristaltic Direction|Roux-en-Y Gastrointestinal Anastomosis|Gastric Cancer
Interventions: PROCEDURE: Direction procedure of gastrointestinal anastomosis in Roux-en-Y reconstruction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Capillary Refill Time Calculated With a Video-assisted Method Has a Better Reproducibility Than Visual Method in Critically Ill Patients
Status: COMPLETED
Conditions: Intensive Care Unit|Mortality|Reliability
Interventions: OTHER: time of cutaneous recoloration|OTHER: video assisted cutaneous recoloration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: NOL Guided Analgesia During Elective Laparoscopic Surgery Under General Anesthesia
Status: RECRUITING
Conditions: Intraoperative Analgesia
Interventions: DEVICE: Nociception level index (NOL™)|OTHER: Fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Comparison of ESP Block and M-TAPA Block Efficiency in Postoperative Analgesia Management in Nephrectomy Cases
Status: NOT_YET_RECRUITING
Conditions: Pain, Postoperative
Interventions: OTHER: NRS 0. hour|OTHER: NRS 6. Hour|OTHER: NRS 12. Hour|OTHER: NRS 24. Hour
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Mother-Infant Psychoanalysis Project of Stockholm
Status: COMPLETED
Conditions: Mother-infant Relational Disturbances
Interventions: OTHER: Treatment as Usual at Child Health Centre|OTHER: Mother-Infant Psychoanalytic treatment (MIP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Implitapide in Patients With Heterozygous Familial Hypercholesterolemia (HeFH) on Maximal Concurrent Lipid-Lowering Therapy
Status: TERMINATED
Conditions: Familial Hypercholesterolemia
Interventions: DRUG: Implitapide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Phase II Study of ctDNA-guided Encorafenib Plus Cetuximab Retreatment in Patients BRAF V600E Mutated mCRC
Status: RECRUITING
Conditions: Colorectal Cancer
Interventions: DRUG: Cetuximab|DRUG: Encorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Inspiratory Muscle Training in Post COVID-19 Patients
Status: UNKNOWN
Conditions: Covid19|Infective Pneumonia
Interventions: OTHER: Inspiratory Muscle Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immuno-modulation in Amyotrophic Lateral Sclerosis- a Phase II Study of Safety and Activity of Low Dose Interleukin-2
Status: COMPLETED
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DRUG: Placebo|DRUG: 1.0 MIU IL-2 per day|DRUG: 2.0 MIU IL-2 per day
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Enhancing Recovery in Early Schizophrenia
Status: RECRUITING
Conditions: Schizophrenia
Interventions: DRUG: Cannabidiol as add-on|DRUG: Placebo as add-on
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Computer-Assisted Fixation of Trochanteric Femur Fractures
Status: RECRUITING
Conditions: Hip Fractures
Interventions: DEVICE: Stryker© ADAPT™ platform|RADIATION: Traditional fluoroscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Carboxylesterase-Expressing Allogeneic Neural Stem Cells and Irinotecan Hydrochloride in Treating Patients With Recurrent High-Grade Gliomas
Status: ACTIVE_NOT_RECRUITING
Conditions: Recurrent Anaplastic Astrocytoma|Recurrent Anaplastic Oligoastrocytoma|Recurrent Anaplastic Oligodendroglioma|Recurrent Glioblastoma|Recurrent Gliosarcoma|Recurrent Malignant Glioma|Recurrent WHO Grade III Glioma
Interventions: BIOLOGICAL: Carboxylesterase-expressing Allogeneic Neural Stem Cells|DRUG: Irinotecan|DRUG: Irinotecan Hydrochloride|OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacological Study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Benvitimod Cream in the Retreatment of Mild to Moderate Psoriasis
Status: UNKNOWN
Conditions: Psoriasis
Interventions: DRUG: Benvitimod Cream|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: mHealth Intervention to Increase Physical Activity in Prediabetes and Type 2 Diabetes
Status: RECRUITING
Conditions: Type 2 Diabetes|PreDiabetes
Interventions: BEHAVIORAL: mHealth|BEHAVIORAL: phone counselling|BEHAVIORAL: Fitbit tracker|BEHAVIORAL: brief advice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Fluorescence, Light-microscopy, Ultrasound Integrated / Intraoperative Diagnosis to MAXimise Resection
Status: UNKNOWN
Conditions: Patients With Radiological, Clinical and Anamnestic Picture Compatible With a New Diagnosis of Glioblastoma
Interventions: OTHER: Fluid MAX group
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Prophylaxis Against Tuberculosis (TB) in Patients With Human Immunodeficiency Virus (HIV) Infection and Suspected Latent Tuberculous Infection
Status: COMPLETED
Conditions: HIV Infections|Tuberculosis
Interventions: DRUG: Isoniazid|DRUG: Pyridoxine hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: Effect of Rocuronium and Sugammadex Under Sevoflurane and Desflurane Anesthesia in Children
Status: COMPLETED
Conditions: Anesthetics, Inhalation|Neuromuscular Blockade|Anesthesia, General
Interventions: DRUG: Rocuronium|DRUG: Sugammadex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Study to Evaluate Induction Chemotherapy Using Docetaxel, Cisplatin and Fluorouracil in Concurrence With Intensity-modulated Radiotherapy for Local Recurrent Nasopharyngeal Carcinoma (NPC)
Status: COMPLETED
Conditions: Nasopharyngeal Carcinoma
Interventions: DRUG: Docetaxel, Cisplatin, 5-FU and Cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pharmacodynamic Study of Sirolimus and Metformin in Patients With Advanced Solid Tumors
Status: COMPLETED
Conditions: Breast Neoplasms|Lung Neoplasms|Cancer of Liver|Lymphoma|Cancer of Kidney
Interventions: DRUG: Metformin XR|DRUG: Delayed Metformin|DRUG: Sirolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prophylactic Alpha-blockers in the Prevention of Urinary Retention Post Inguinal Hernia Repair
Status: UNKNOWN
Conditions: Urinary Retention|Inguinal Hernia
Interventions: DRUG: Tamsulosin|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of a New CBT for People With Alzheimer's Disease and Their Caregivers
Status: COMPLETED
Conditions: Alzheimer Disease
Interventions: BEHAVIORAL: Cognitive-Behavioral group therapy|BEHAVIORAL: Non directive support Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MRI Radiomics Assessing Neoadjuvant Chemotherapy in Breast Cancer to Predict Lymph Node Metastasis and Prognosis(RBC-02)
Status: RECRUITING
Conditions: Invasive Breast Cancer|Neoadjuvant Chemotherapy|Radiomics|Axillary Lymph Node|Prognosis
Interventions: OTHER: No interventions
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Different Training Programs on Patients With Chronic Diseases
Status: UNKNOWN
Conditions: Hypertension|Hypertension Complicated With Type 2 Diabetes|Walking|Chinese Square Dancing
Interventions: BEHAVIORAL: Walking|BEHAVIORAL: Chinese square dancing group|BEHAVIORAL: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety And Anti-Inflammatory Effect Of SB681323 In Patients With Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive|Chronic Obstructive Pulmonary Disease (COPD)
Interventions: DRUG: SB681323
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Delayed Primary Closure Using Negative Pressure Wound Therapy
Status: RECRUITING
Conditions: Infection Abdominal
Interventions: DEVICE: Abthera|PROCEDURE: Open adbdomen for post-laparotomy without NPWT device
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Breathing Exercises in Asthma Targeting Dysfunctional Breathing
Status: ACTIVE_NOT_RECRUITING
Conditions: Dysfunctional Breathing in Asthma
Interventions: OTHER: Breathing Exercises|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Alirocumab Versus Usual Care on Top of Maximally Tolerated Statin Therapy in Patients With Type 2 Diabetes and Mixed Dyslipidemia (ODYSSEY DM-Dyslipidemia)
Status: COMPLETED
Conditions: Dyslipidemia
Interventions: DRUG: Alirocumab|DRUG: Statins|DRUG: Ezetimibe|DRUG: Fenofibrate|DRUG: Nicotinic acid|DRUG: Omega-3 fatty acids|DRUG: Antihyperglycemic Drug
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Application of Oral Mucosal Epithelial Cell Sheets Cultivated on Amino Membrane in Patients Suffering From Corneal Stem Cell Insufficiency or Symblepharon.
Status: TERMINATED
Conditions: Limbal Insufficiency|Symblepharon
Interventions: PROCEDURE: Cultured oral mucosa cell sheet transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Performance and Safety Evaluation of Inion CompressOn Screw in Foot and Ankle Surgeries. PMCF Investigation
Status: RECRUITING
Conditions: Medial Malleolus Fracture|Lisfranc Injury|Lisfranc Fracture|Talus Fracture|Calcaneus Fracture|Navicular Fracture|Deformity, Foot|Ankle Fractures|Foot Fracture|Fractures, Bone|Fracture of Foot|Foot Deformities|Foot Injury|Feet Deformity Tarsus|Metatarsalgia|Hallux Rigidus|Hallux Valgus|Deformity of Toe|Deformity of Foot
Interventions: PROCEDURE: Operation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Participants With Breast Cancer
Status: RECRUITING
Conditions: Inoperable, Locally Advanced or Metastatic, ER-positive Breast Cancer
Interventions: DRUG: Giredestrant|DRUG: Abemaciclib|DRUG: Ipatasertib|DRUG: Inavolisib|DRUG: Ribociclib|DRUG: Everolimus|DRUG: Samuraciclib|DRUG: PH FDC SC|DRUG: Palbociclib|DRUG: Atezolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Inhibitory Control Smartphone App
Status: ACTIVE_NOT_RECRUITING
Conditions: Drinking, Alcohol|Drinking Behavior
Interventions: BEHAVIORAL: Control App Version|BEHAVIORAL: Standard App Version|BEHAVIORAL: Experimental, Feedback App Version
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: A Drug-Drug Interaction Study of Furosemide and PA21
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: PA21 and Furosemide with food|DRUG: No PA21; Furosemide with food|DRUG: PA21 with food and Furosemide 2hrs later
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The wEight Management in Renal Transplant Online Study (ExeRTiOn)
Status: COMPLETED
Conditions: Kidney Transplant; Complications|Obesity|Physical Activity|Weight Gain|Health Behavior
Interventions: OTHER: ExeRTiOn
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Simultaneous Dual Stimulation on Freezing of Gait in Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: DEVICE: rTMS and tDCS|DEVICE: rTMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating the Safety and Tolerability of QRL-201 in ALS
Status: RECRUITING
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DRUG: Multiple ascending doses of QRL-201|DRUG: Multiple ascending doses of Placebo|DRUG: QRL-201|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Research for Prevention and Treatment of NSAIDs Related Gastrointestinal Side Effects
Status: UNKNOWN
Conditions: Non-steroidal Anti-inflammatory Drug Adverse Reaction
Interventions: DRUG: part1:teprenone|DRUG: part1:EAC-T|DRUG: part1:EA-EMC-T|DRUG: part1:teprenone|DRUG: part2:GGA group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Ultrasound Prediction of POPP in Active Labor
Status: NOT_YET_RECRUITING
Conditions: Labor Complication|Fetal Head to Enter Pelvic Brim; Failure, Affecting Fetus or Newborn
Interventions: DIAGNOSTIC_TEST: Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Drug-drug Interaction Trial to Evaluate the Pharmacokinetics Effect of Rifampicin on Famitinib
Status: COMPLETED
Conditions: Healthy Adult Subjects
Interventions: DRUG: Famitinib capsule|DRUG: Rifampicin capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Irinotecan and Bevacizumab for Recurrent Ovarian Cancer
Status: COMPLETED
Conditions: Ovarian Cancer|Fallopian Tube Cancer|Primary Peritoneal Carcinoma
Interventions: DRUG: Irinotecan|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Psilocybin Cancer Anxiety Study
Status: COMPLETED
Conditions: Cancer
Interventions: DRUG: Psilocybin|DRUG: Niacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Therapeutic Evaluation(Both Short-term and Long-term Outcome) of Minimal Invasive Radical Antegrade Modular Pancreatosplenectomy for Left-sided Pancreatic Cancer Patients
Status: RECRUITING
Conditions: Pancreatic Cancer|Surgery
Interventions: PROCEDURE: Minimal Invasive RAMPS|PROCEDURE: Open RAMPS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy, Safety, and Tolerability of Tapentadol ER Compared With Placebo in Patients With Chronic, Painful Diabetic Peripheral Neuropathy
Status: COMPLETED
Conditions: Diabetic Peripheral Neuropathy
Interventions: DRUG: Tapentadol extended release (ER)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of Vascular Endothelial Growth Factor (VEGF), Bevacizumab, in Combination With Cytotoxic Chemotherapy for Endometrial Cancer
Status: COMPLETED
Conditions: Endometrial Carcinoma
Interventions: DRUG: carboplatin, paclitaxel, and bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pancreatic Enzyme Replacement Therapy for Acute Pancreatitis-Associated Exocrine Pancreatic Insufficiency
Status: RECRUITING
Conditions: Exocrine Pancreatic Insufficiency
Interventions: DRUG: Pancrelipase Capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lymphocyte Markers As Predictors Of Responsiveness To Rituximab Among Patients With Idiopathic Nephrotic Syndrome
Status: RECRUITING
Conditions: Nephrotic Syndrome
Interventions: DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PEDS-C: Pegylated Interferon +/- Ribavirin for Children With Hepatitis C
Status: COMPLETED
Conditions: Chronic Hepatitis C
Interventions: DRUG: Pegylated Interferon/ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of a Personalized Sleep Improvement App From SleepScore Labs
Status: RECRUITING
Conditions: Health Behavior
Interventions: BEHAVIORAL: Dein Schlaf. Dein Tag. sleep improvement application powered by SleepScore
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Initiation of Long-term Non-invasive Ventilation in COPD
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DEVICE: Transcutaneous measurements of PCO2|DEVICE: Telemonitoring|DEVICE: EMG|OTHER: Home initiation of NIV|OTHER: Inhospital initiation of NIV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Efficacy, Safety and Immunogenicity of Influenza Vaccine in Healthy Subjects (Aged 6 to <72 Months) Versus Control Vaccines
Status: COMPLETED
Conditions: Influenza, Human
Interventions: BIOLOGICAL: Adjuvanted trivalent inactivated subunit influenza vaccine|BIOLOGICAL: Non-adjuvanted trivalent inactivated subunit influenza vaccine or non-adjuvanted trivalent inactivated split influenza vaccine|BIOLOGICAL: Meningococcal C conjugate vaccine or tick-borne encephalitis vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Study of the Efficacy of IAMT as an Assessment Tool for Prediction of Progression of Parkinson's Disease
Status: RECRUITING
Conditions: Parkinson Disease
Interventions: BEHAVIORAL: Improvised Active Music Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: FATE-NK100 as Monotherapy and in Combination With Monoclonal Antibody in Subjects With Advanced Solid Tumors
Status: COMPLETED
Conditions: HER2 Positive Gastric Cancer|Colorectal Cancer|Head and Neck Squamous Cell Carcinoma|EGFR Positive Solid Tumor|Advanced Solid Tumors|HER2-positive Breast Cancer|Hepatocellular Carcinoma|Non Small Cell Lung Cancer|Renal Cell Carcinoma|Pancreatic Cancer|Melanoma
Interventions: DRUG: FATE-NK100|DRUG: Cetuximab|DRUG: Trastuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of S-ketamine and Continuous Iliac Fascia Space Block on Perioperative Neurological Cognitive Impairment and Postoperative Rehabilitation in Elderly Patients With Hip Fracture
Status: UNKNOWN
Conditions: Hip Fractures
Interventions: DRUG: S-Ketamine|DEVICE: Continuous iliac fascia space block|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT