pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Peritransplant Deoxyspergualin in Islet Transplantation in Type 1 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: BIOLOGICAL: Allogeneic Pancreatic Islet Cells|DRUG: Deoxyspergualin|BIOLOGICAL: Antithymocyte globulin|BIOLOGICAL: Daclizumab or basiliximab|DRUG: Sirolimus|DRUG: Tacrolimus|BIOLOGICAL: Etanercept
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nivolumab and Ipilimumab in Treating Patients With Metastatic/Recurrent ACC of All Sites and Non-ACC Salivary Gland Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Major Salivary Gland Carcinoma|Minor Salivary Gland Carcinoma|Recurrent Salivary Gland Carcinoma|Stage IV Major Salivary Gland Carcinoma|Stage IVA Major Salivary Gland Carcinoma|Stage IVB Major Salivary Gland Carcinoma|Stage IVC Major Salivary Gland Carcinoma
Interventions: BIOLOGICAL: Ipilimumab|OTHER: Laboratory Biomarker Analysis|BIOLOGICAL: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Detection of Efflux Pump Genes Mediating Ciprofloxacin Resistance in Staphylococcus Aureus Isolates in Sohag University Hospitals
Status: NOT_YET_RECRUITING
Conditions: Patients withInfections Caused by S.Aureus Like Skin Infections , Chest Infections , Surgical Site Infections , and Urinary Tract Infections
Interventions: DIAGNOSTIC_TEST: antibiotic sensitivity
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Management of Fragments During Ureteroscopy
Status: COMPLETED
Conditions: Urinary Stones
Interventions: PROCEDURE: Ureteroscopy, Holmium Laser lithotripsy and active retrieval of fragments|PROCEDURE: Ureteroscopy, Holmium laser lithotripsy, no intent to retrieve any remaining fragment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Efficacy Comparison of Two Preoperative Skin Antisepsis Preparations in Colorectal Surgery
Status: COMPLETED
Conditions: Colorectal Surgery
Interventions: DRUG: 2% Chlorhexidine Gluconate/70% Isopropyl Alcohol|DRUG: Iodine Povacrylex/74% Isopropyl Alcohol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of Triple-site Ventricular Pacing in Patients Who Have Not Responded to Conventional Dual Ventricular Site Cardiac Resynchronization Therapy
Status: COMPLETED
Conditions: Heart Failure
Interventions: PROCEDURE: Upgrade to triple ventricular site CRT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prophylactic Intravesical Chemotherapy to Prevent Bladder Tumors After Nephroureterectomy for Primary Upper Urinary Tract Urothelial Carcinomas
Status: UNKNOWN
Conditions: Upper Tract Urothelial Carcinoma|Bladder Recurrence
Interventions: DRUG: pharmorubicin or pirarubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Mass Balance, Pharmacokinetics, Biotransformation and Bioavailability Study of ODM-201 in Healthy Male Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: ODM-201 300 mg tablet|DRUG: intravenous14C-ODM-201|DRUG: 300 mg 14C-ODM-201 oral solution
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Structured Treatment of Pain (STOP) Study
Status: COMPLETED
Conditions: Traumatic Brain Injury|Chronic Pain
Interventions: BEHAVIORAL: Self-Management #1|BEHAVIORAL: Self-Management #2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Biomarkers in Samples From Patients With Endometrial Cancer
Status: WITHDRAWN
Conditions: Lynch Syndrome|Recurrent Uterine Corpus Carcinoma|Stage I Uterine Corpus Cancer|Stage II Uterine Corpus Cancer|Stage III Uterine Corpus Cancer|Stage IV Uterine Corpus Cancer
Interventions: OTHER: Laboratory Biomarker Analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Randomized Study of Beta Interferon and Thalidomide in Patients With Adrenoleukodystrophy
Status: COMPLETED
Conditions: Adrenoleukodystrophy
Interventions: DRUG: glyceryl trierucate|DRUG: glyceryl trioleate|DRUG: interferon beta|DRUG: thalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Modafinil to Improve Fatiguability
Status: NOT_YET_RECRUITING
Conditions: Cancer-related Cognitive Difficulties|Cancer-related Problem/Condition|Fatigue
Interventions: DRUG: Modafinil|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Brainshuttle AD: A Multiple Ascending Dose Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of RO7126209 Following Intravenous Infusion in Participants With Prodromal or Mild to Moderate Alzheimer's Disease
Status: RECRUITING
Conditions: Alzheimers Disease
Interventions: DRUG: RO7126209|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Dosage Study of RAD001 (Everolimus) in Combination With Current Standard of Care to Treat Advanced Solid Tumors.
Status: COMPLETED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific|Cancer
Interventions: DRUG: capecitabine/oxaliplatin/bevacizumab/RAD001 (XELOX-A-Ev)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Digital Tomosynthesis for Detection and Case Management of Scaphoid and Distal Radius Fractures: A VolumeRAD Data Collection Study
Status: UNKNOWN
Conditions: Distal Radius Fracture|Scaphoid Fracture
Interventions: DEVICE: DTS|DEVICE: X-ray|DEVICE: MRI or CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: An Open-Label Trial of Dexlansoprazole 60mg for the Relief of Heartburn During the Fasting Month of Ramadan
Status: COMPLETED
Conditions: GERD|Proton Pump Inhibitor
Interventions: DRUG: Dexlansoprazole 60 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: E GFR TKI and EGF-P TI C Ombination in EGFR mutA nt NSCL C
Status: COMPLETED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: EGFR-TK Inhibitor|BIOLOGICAL: EGF-PTI|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 1b Study of Thymosin Beta 4 in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Recombinant Human Thymosin β4|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Is There a Benefit of Postoperative ICU Management After Elective Surgery in Critical Ill Patients?
Status: UNKNOWN
Conditions: Postoperative Care|Intensive Care
Interventions: OTHER: Postoperative care in Intensive care unit (ICU)|OTHER: Postoperative care in standard ward
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Haplo-identical Hematopoietic Stem Cell Transplantation Following Reduced-intensity Conditioning in Children With Neuroblastoma
Status: UNKNOWN
Conditions: Neuroblastoma
Interventions: DRUG: Busulfan - Fludarabine - TBI
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Inactivated Influenza A/H5N1 Vaccine in the Elderly
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Influenza A/H5N1 Vaccine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Safety and Efficacy of CB-03-01 Cream, 1% in Subjects With Facial Acne Vulgaris (25)
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: CB-03-01 cream, 1%|DRUG: Vehicle cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: RE002 T Cell Injection for the Treatment of KRAS G12D Mutated Solid Tumors
Status: NOT_YET_RECRUITING
Conditions: KRAS G12D|T Cell Therapy
Interventions: BIOLOGICAL: RE002 T cell
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Postoperative Pain After Total Knee Arthroplasy Using Intravenous Lidocaine Infusion
Status: WITHDRAWN
Conditions: Total Knee Arthroplasty
Interventions: PROCEDURE: Continuous femoral catheter block|DRUG: Lidocaine|OTHER: Preservative free normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Determine the Tolerability, Safety and Pharmacokinetics of Ketorolac Tromethamine by Intranasal Administration in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Ketorolac tromethamine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Challenge Non-Typhoidal Salmonella (CHANTS) Study
Status: RECRUITING
Conditions: Salmonella Infections|Salmonella Typhimurium|Non-typhoidal Salmonella (NTS)|Invasive Non-Typhoidal Salmonella Disease|Communicable Disease|Infections, Bacterial|Enteric Fever (Not Typhoid)|Gastroenteritis
Interventions: BIOLOGICAL: Salmonella Typhimurium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Evaluate Pharmacokinetic (PK) and Safety of GSK1265744 in Subjects With Hepatic Impairment and Control Healthy Volunteers
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: GSK1265744 30mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EFFECTS OF ACUPUNCTURE ON LEG MUSCLE STRENGTH
Status: COMPLETED
Conditions: Health, Subjective|Muscle Strength
Interventions: DEVICE: Press tack needle|DEVICE: Plesterin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Weekly Gemcitabine, Epirubicin, and Docetaxel in Locally Advanced or Inflammatory Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Gemcitabine|DRUG: Epirubicin|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Telephone-Based Re-education for Hp Eradication
Status: COMPLETED
Conditions: Helicobacter Pylori Infection
Interventions: BEHAVIORAL: telephone-based re-education|BEHAVIORAL: First education at the clinic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Fludarabine Phosphate, Clofarabine, and Busulfan With Vorinostat in Treating Patients With Acute Leukemia in Remission or Relapse Undergoing Donor Stem Cell Transplant
Status: COMPLETED
Conditions: Acute Lymphoblastic Leukemia in Remission|Acute Myeloid Leukemia in Remission|Allogeneic Hematopoietic Stem Cell Transplantation Recipient|Myelodysplastic Syndrome|Previously Treated Myelodysplastic Syndrome|Recurrent Acute Lymphoblastic Leukemia|Recurrent Acute Myeloid Leukemia
Interventions: PROCEDURE: Allogeneic Bone Marrow Transplantation|PROCEDURE: Allogeneic Hematopoietic Stem Cell Transplantation|BIOLOGICAL: Anti-Thymocyte Globulin|DRUG: Busulfan|DRUG: Clofarabine|DRUG: Fludarabine Phosphate|PROCEDURE: Peripheral Blood Stem Cell Transplantation|OTHER: Pharmacological Study|DRUG: Vorinostat
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Scavenging of Reactive Carbonyl Species by Apple Polyphenols in Human
Status: COMPLETED
Conditions: Human Health|Polyphenols|Pharmacokinetics
Interventions: DIETARY_SUPPLEMENT: Apple consumption|DIETARY_SUPPLEMENT: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Gemcitabine-based Induction Chemotherapy Combined With Concurrent Chemoradiotherapy in Locally Advanced Nasopharyngeal Carcinoma
Status: RECRUITING
Conditions: Nasopharyngeal Carcinoma
Interventions: DRUG: Gemcitabine combined with cisplatin induction chemotherapy|DRUG: concurrent chemoradiotherapy with gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chronic Pain Risk Associated With Menstrual Period Pain
Status: COMPLETED
Conditions: Cystitis, Interstitial|Dysmenorrhea|Migraine Disorders|Pelvic Pain|Endometriosis|Visceral Pain|Chronic Pain
Interventions: DRUG: cyclic microgestin 1/20|DRUG: continuous microgestin 1/20
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Biological Therapy in Treating Children With Refractory or Recurrent Neuroblastoma or Other Tumors
Status: COMPLETED
Conditions: Melanoma (Skin)|Neuroblastoma|Sarcoma|Unspecified Childhood Solid Tumor, Protocol Specific
Interventions: BIOLOGICAL: hu14.18-IL2 fusion protein
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Finnish Study of Intraoperative Irrigation Versus Drain Alone After Evacuation of Chronic Subdural Hematoma (FINISH)
Status: COMPLETED
Conditions: Chronic Subdural Hematoma
Interventions: PROCEDURE: Intraoperative irrigation|PROCEDURE: No irrigation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Povidone-Iodine Rinses as an Adjuvant Therapy Post-Operatively
Status: UNKNOWN
Conditions: Chronic Rhinosinusitis (Diagnosis)
Interventions: DRUG: Povidone-Iodine|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: The Use of Cervical Length to Reduce Hospital Stay in Women Admitted Because of Preterm Labor.
Status: COMPLETED
Conditions: Labor, Premature|Cervical Length
Interventions: PROCEDURE: Cervical length ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Fuchs' Endothelial Dystrophy: Clinical Characteristics, Treatment Outcome, and Pathology
Status: COMPLETED
Conditions: Fuchs' Endothelial Corneal Dystrophy
Interventions: PROCEDURE: DSAEK surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Amino Acids in Ileal Pouch-anal Anastomosis for Ulcerative Colitis
Status: UNKNOWN
Conditions: Ulcerative Colitis
Interventions: DIETARY_SUPPLEMENT: Vaminolac|OTHER: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Education Program on Increasing Osteoporosis Awareness Given to Women Aged 18-49
Status: COMPLETED
Conditions: Osteoporosis Risk
Interventions: OTHER: Education Program on Increasing Osteoporosis Awareness Given to Women Aged 18-49. The research is carry out as a randomized controlled experimental in a pretest-posttest design.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Wei Nasal Jet Tube vs Nasal Cannula Oxygen Support in Gastrointestinal Endoscopy Patients
Status: COMPLETED
Conditions: Supraglottic Airway Obstruction|Airway Complication of Anesthesia|Airway Obstruction|Anesthesia Complication|Bronchospasm|Nasal Bleeding|Oxygen Deficiency
Interventions: DEVICE: Wei Nasal Jet Tube|DEVICE: Nasal Cannula Oxygen Support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Testing SIROLIMUS in Beta-thalassemia Transfusion Dependent Patients (THALA-RAP)
Status: UNKNOWN
Conditions: Beta-Thalassemia
Interventions: DRUG: Sirolimus 0.5 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Treatment Effect of Chinese Medicine Formula on Uremic Pruritus
Status: UNKNOWN
Conditions: Uremic Pruritus
Interventions: DRUG: Xiao-Feng-San+Shian-Fang-Hwa-Ming-Yiin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Subcutaneous ACTEMRA on Inflamed Atherosclerotic Plaques in Patients With Rheumatoid Arthritis
Status: TERMINATED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: tocilizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influenza Vaccine Revaccination in Ambulatory Elderly Subjects
Status: COMPLETED
Conditions: Influenza|Orthomyxovirus Infection|Myxovirus Infection
Interventions: BIOLOGICAL: Influenza Virus Vaccine USP Trivalent Types A and B|BIOLOGICAL: Influenza Virus Vaccine USP Trivalent Types A and B|BIOLOGICAL: Influenza Virus Vaccine USP Trivalent Types A and B|BIOLOGICAL: Influenza Virus Vaccine USP Trivalent Types A and B|BIOLOGICAL: Influenza Virus Vaccine USP Trivalent Types A and B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study to Evaluate the Safety and Efficacy of ABT-712 in Subjects With Moderate to Severe Chronic Low Back Pain (CLBP)
Status: COMPLETED
Conditions: Chronic Low Back Pain
Interventions: DRUG: ABT-712|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of a High-fat vs. High-sugar Diet on Liver Fat Accumulation and Metabolism
Status: COMPLETED
Conditions: Fat; Liver|NAFLD
Interventions: OTHER: High-fat, low-carbohydrate|OTHER: Low-fat, high-carbohydrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of Zetomipzomib (KZR-616) in Patients With Active Lupus Nephritis (PALIZADE)
Status: RECRUITING
Conditions: Lupus Nephritis
Interventions: DRUG: zetomipzomib|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transanal Total Mesorectal Excision Versus Laparoscopic TME for Rectal Cancer
Status: COMPLETED
Conditions: Rectal Neoplasms
Interventions: PROCEDURE: conventional laparoscopic total mesentery excision|PROCEDURE: transanal hybrid-laparoscopic total mesentery excision
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety and Efficacy of CSB-001 Ophthalmic Solution 0.1% in Neurotrophic Keratitis Subjects
Status: COMPLETED
Conditions: Neurotrophic Keratitis
Interventions: BIOLOGICAL: CSB-001 Ophthalmic Solution 0.1%|BIOLOGICAL: Vehicle Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Implementing Fragmentomics Into Real World Screening IntervenTions to Evaluate Clinical Utility Among Individuals With Elevated Risk for Lung Cancer
Status: RECRUITING
Conditions: Lung Cancer
Interventions: DIAGNOSTIC_TEST: Ability to order FirstLook™|OTHER: Continuing Medical Education for Lung Cancer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Therapy for Locally Advanced Breast Cancer Using Doxil, Paclitaxel, and Cyclophosphamide With Avastin
Status: COMPLETED
Conditions: Invasive Breast Cancer
Interventions: DRUG: Doxil, Paclitaxel, Cyclophosphamide, Avastin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TruFreeze™ Airway Obstruction: TAO STUDY
Status: WITHDRAWN
Conditions: Lung Disease Airways|Lung Diseases, Obstructive|Airway; Obstruction, With Emphysema|Airway Obstruction
Interventions: DEVICE: spray cryotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Atezolizumab in Combination With Carboplatin Plus Etoposide to Investigate Safety and Efficacy in Patients With Untreated Extensive-Stage Small Cell Lung Cancer
Status: COMPLETED
Conditions: Small Cell Lung Carcinoma
Interventions: DRUG: Atezolizumab|DRUG: Carboplatin|DRUG: Etoposide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Prolonged Multimodal Analgesic Regimen on Post Hospital Discharge Opioid Use and Pain Control After Primary Total Knee Arthroplasty
Status: COMPLETED
Conditions: Osteo Arthritis Knee
Interventions: DRUG: Oxycodone|DRUG: Tramadol|DRUG: Tylenol|DRUG: Meloxicam|DRUG: Gabapentin|DRUG: Metaxalone|DRUG: Esomeprazole 20mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 3,4-Diaminopyridine Use in Lambert-Eaton Myasthenic Syndrome(LEMS) and Congenital Myasthenic Syndromes (CMS)
Status: APPROVED_FOR_MARKETING
Conditions: Lambert-Eaton Myasthenic Syndrome|Congenital Myasthenic Syndrome
Interventions: DRUG: 3,4-DIAMINOPYRIDINE
Study Type: EXPANDED_ACCESS
Clinical trial: Simvastatin and Diastolic Dysfunction
Status: COMPLETED
Conditions: Diastolic Dysfunction|Hypertension
Interventions: DRUG: Simvastatin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Education for Osteoporosis in Persons With Existing Fractures
Status: COMPLETED
Conditions: Osteoporosis
Interventions: BEHAVIORAL: Osteoporosis Prevention and Self-Management Course|BEHAVIORAL: Introductory education session on osteoporosis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Performance of Ellume·Lab Group A Strep Test Versus Culture for the Rapid Detection of Group A Streptococcus in Patients With Acute Pharyngitis.
Status: COMPLETED
Conditions: Group A Streptococcal Infection
Interventions: DIAGNOSTIC_TEST: ellume.lab Group A Streptococcus Test
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Obinutuzumab in Combination With Lenalidomide in Relapsed or Refractory Marginal Zone Lymphoma
Status: RECRUITING
Conditions: Marginal Zone Lymphoma
Interventions: DRUG: Obinutuzumab|DRUG: lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Esomeprazole Bioavailability Study With 40 mg Oral Single Dose Fasted and Fed Administration
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: 40 mg Esomeprazole Mepha (Mepha Ltd., Switzerland)|DRUG: INexium 40 mg MUPS tablets (AstraZeneca, France)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Effectiveness of a Physical Activity and Diet Program in Patients With Psychotic Disorder (CapiCor)
Status: COMPLETED
Conditions: Schizophrenic Disorders|Schizoaffective Disorders|Bipolar Disorders
Interventions: BEHAVIORAL: Physical and diet educational group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Metformin in Reducing Fatigue in Long COVID in Adolescents
Status: NOT_YET_RECRUITING
Conditions: Long COVID
Interventions: DRUG: Metformin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: SToP: Venous Thromboembolism Screening in the Trauma Population
Status: UNKNOWN
Conditions: Venous Thromboembolism|Deep Vein Thrombosis|Trauma, Multiple
Interventions: OTHER: Duplex ultrasound surveillance|OTHER: No ultrasound surveillance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Combination of Olmesartan and Hydrochlorothiazide in Essential Hypertension
Status: COMPLETED
Conditions: Essential Hypertension
Interventions: DRUG: olmesartan medoxomil (OM)+ hydrochlorothiazide (HCTZ) tablets|DRUG: olmesartan medoxomil (OM)/ hydrochlorothiazide (HCTZ) 20mg/25mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Mandibular Splint vs Botox Injection in Lateral Pterygoid on Cervical Muscle Activity in Patients With Temporomandibular Disorders
Status: RECRUITING
Conditions: Mandibular Splint|Botox|Lateral Pterygoid|Cervical Muscle Activity|Temporomandibular Disorders
Interventions: DRUG: Botox injection|DRUG: Mandibular stabilization splint|DRUG: Muscle relaxant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Empagliflozin and Red Blood Cell 2,3-biphosphoglycerate Levels
Status: RECRUITING
Conditions: Hematocrit Change|Cardiovascular Prevention|Empagliflozin|SGLT2-Inhibitors|Tissue Oxygenation
Interventions: DRUG: Empagliflozin10Mg Tab
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: High Resolution Retina Imaging
Status: UNKNOWN
Conditions: Retinitis Pigmentosa|Maculopathy, Age Related|Macular Dystrophy|Macular Edema|Retinal Degeneration|Diabetic Retinopathy|Occlusion Retinal Vein|Hypertension
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Pregabalin Versus Venlafaxine XR and Placebo in the Treatment of Generalized Anxiety Disorder
Status: COMPLETED
Conditions: Anxiety
Interventions: DRUG: Pregabalin|DRUG: Venlafaxine XR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Mitigating Mental Health Issues Among Women's Sport Student-Athletes Through a Moderate-Intensity Exercise Intervention
Status: COMPLETED
Conditions: Depression|Anxiety|Stress, Psychological
Interventions: BEHAVIORAL: Moderate-Intensity Indoor Cycling Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phototherapy Applied in Association With Muscular Training
Status: COMPLETED
Conditions: Muscle Adaptation
Interventions: DEVICE: Active or Placebo Phototherapy (MR4)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Optimizing an mHealth Intervention to Change Food Purchasing Behaviors for Cancer Prevention
Status: COMPLETED
Conditions: Cancer
Interventions: BEHAVIORAL: Location-triggered notification|BEHAVIORAL: Reflections on benefits of change|BEHAVIORAL: Coach monitoring|BEHAVIORAL: Household support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: An Innovative Care-improvement Smartphone-based Perioperative Solution for Women Undergoing Breast Cancer Surgery
Status: UNKNOWN
Conditions: Breast Cancer Female|Surgery
Interventions: OTHER: iCareBreast|OTHER: Routine care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Testing of HIV Protease Inhibitors to Suppress Inflammation and Improve Cardio Pulmonary Hemodynamics in Subjects With Pulmonary Arterial Hypertension
Status: UNKNOWN
Conditions: Pulmonary Arterial Hypertension
Interventions: DRUG: saquinavir and ritonavir|DRUG: saquinavir and ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tranexamic Acid for the Prevention of Postpartum Haemorrhage
Status: UNKNOWN
Conditions: Postpartum Hemorrhage
Interventions: DRUG: Tranexamic Acid 100 milligram/Milliliter|DRUG: Oxytocin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Cyclophosphamide as Graft-versus-host Prophylaxis After Allogeneic Stem Cell Transplantation for Multiple Myeloma
Status: UNKNOWN
Conditions: Multiple Myeloma
Interventions: DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lu AG06466 in Participants With Post Traumatic Stress Disorder (PTSD)
Status: COMPLETED
Conditions: PTSD
Interventions: DRUG: Lu AG06466|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of ATG003 in Patients With AMD Receiving Anti-VEGF
Status: COMPLETED
Conditions: Age-Related Macular Degeneration
Interventions: DRUG: ATG003 (mecamylamine)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Safety and Efficacy of New Infant Formula in Infantile Colic
Status: TERMINATED
Conditions: Infantile Colic
Interventions: OTHER: control formula|OTHER: intervention formula 1|OTHER: intervention formula 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of EPD on the Lumbar Acoustic Window at Term Pregnancy
Status: COMPLETED
Conditions: Effects of; Anesthesia, Spinal and Epidural, in Pregnancy
Interventions: DEVICE: PLL Length Measured through US
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Phase II Trial of Dose-dense Paclitaxel and Cisplatin as Neo-adjuvant Chemotherapy for Operable Stage II and IIA NSCLC
Status: TERMINATED
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: Paclitaxel, Cisplatin, Pegfilgrastim
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Triple Therapy of Dexamethasone, Palonosetron, and Fosaprepitant as PONV Prevention
Status: ENROLLING_BY_INVITATION
Conditions: Postoperative Nausea and Vomiting|Gynecologic Surgical Procedures|Laparoscopy
Interventions: DRUG: fosaprepitant|DRUG: normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Autologous Bone Marrow-derived Mononuclear Cells for Acute Spinal Cord Injury
Status: UNKNOWN
Conditions: Spinal Cord Injury
Interventions: BIOLOGICAL: Autologous bone marrow-derived mononuclear cells|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect Of Whole Body Vibration Versus Weight Bearing Exercises On Osteoporosis In Breast Cancer Patients After Chemotherapy
Status: COMPLETED
Conditions: Osteoporosis|Breast Cancer
Interventions: OTHER: Whole body vibration group|OTHER: Weight bearing exercises|DRUG: vitamin D supplements and calcium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An Open, Single Center, Non-randomized, Single Arm Clinical Study of Evaluating the Efficacy of Selinexor in the Maintenance Treatment of PTCL
Status: RECRUITING
Conditions: PTCL Patients Who Achieved Complete Response From Frontline Treatment
Interventions: DRUG: Selinexor
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Safety and Efficacy Study of NNZ-2566 in Patients With Mild Traumatic Brain Injury (mTBI)
Status: TERMINATED
Conditions: Concussion
Interventions: DRUG: NNZ-2566|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Predicting Response to Neoadjuvant ATEZOLIZUMAB Plus Carboplatin/Nab Paclitaxel in Resectable Non-squamous NSCLC
Status: RECRUITING
Conditions: NSCLC Stage II|NSCLC, Stage IIIA|NSCLC Stage IIIB
Interventions: DRUG: Atezolizumab 1200 mg abs day 1 q22 (iv)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Does Caudal Block Increase the Incidence of Urethrocutaneous Fistula Formation Following Hypospadias Repair in Infants?
Status: COMPLETED
Conditions: Hypospadias|Urethrocutaneous Fistula
Interventions: DRUG: Caudal block with ropivacaine|DRUG: penile nerve block with bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: NIRS and Exercise Intensity in Patients With FLIA
Status: UNKNOWN
Conditions: Near-Infrared Spectroscopy|Iliac Artery Stenosis|Iliac Artery Disease|Iliac Artery Occlusion
Interventions: OTHER: Cycling test|OTHER: Occlusion tests|DEVICE: NIRS during cycling|DEVICE: CPET|DEVICE: Echo-Doppler examination
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: EUS-guided Biliary Drainage vs. ERCP Assisted Transpapillary Drainage for Malignant Biliary Obstruction
Status: COMPLETED
Conditions: Malignant Biliary Obstruction
Interventions: PROCEDURE: ERCP assisted trans-papillary drainage for malignant biliary obstruction|PROCEDURE: EUS-guide biliary drainage for malignant biliary obstruction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single Arm Trial With Combination of Everolimus and Letrozole in Treatment of Platinum Resistant Relapse or Refractory or Persistent Ovarian Cancer/Endometrial Cancer
Status: UNKNOWN
Conditions: Ovarian Cancer|Endometrial Cancer
Interventions: DRUG: everolimus and letrozole
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Acetabular Posterior Wall Fracture With Anatomical Locking Plate
Status: COMPLETED
Conditions: Fracture of Acetabulum
Interventions: DEVICE: Anatomical locking plate|PROCEDURE: The Reconstructive Plate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Electrical Vestibular Nerve Stimulation (VeNS) in the Management of Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: DEVICE: VeNS device|DEVICE: Sham VeNS device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomised Controlled Trial of Lumbar Drainage to Treat Communicating Hydrocephalus After Severe Intraventricular Hemorrhage
Status: COMPLETED
Conditions: Intracerebral Hemorrhage|Obstructive Hydrocephalus
Interventions: PROCEDURE: Lumbar drainage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multidomain Intervention Program for Older People With Dementia
Status: COMPLETED
Conditions: Dementia|Alzheimer Disease|Dementia, Mixed
Interventions: BEHAVIORAL: Physical activity intervention|BEHAVIORAL: Cognitive stimulation intervention|BEHAVIORAL: Social intervention|OTHER: Management of metabolic and vascular risk factors
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Th17/Treg Cells and IL-23/IL-17 Axis and Early Enteral Nutrition in Sepsis
Status: COMPLETED
Conditions: Sepsis|Immune System Disorder|Enteral Feeding
Interventions: OTHER: enteral nutrition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Sitafloxacin in the Treatment of Acute Exacerbation of Bronchiectasis in Adults
Status: UNKNOWN
Conditions: Acute Exacerbation of Bronchiectasis
Interventions: DRUG: anti-infective therapy sitafloxacin|DRUG: anti-infective therapy levofloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Sevelamer Carbonate on Diabetic Nephropathy
Status: COMPLETED
Conditions: Diabetic Nephropathy
Interventions: DRUG: Sevelamer Carbonate|DRUG: calcium carbonate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Influence of Three Different Formulations of Lachrymal Substitutes on Tear Film Thickness and Other Signs and Symptoms in Patients With Moderate to Severe Dry Eye Syndrome
Status: COMPLETED
Conditions: Dry Eye Syndromes
Interventions: DEVICE: Thealoz Duo Eye Drops|DEVICE: Optive Eye Drops|DEVICE: Systane Ultra Eye Drops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: First-in-Human Study of VB0004 in Healthy Subjects and to Patients With Mild to Moderate Hypertension With Low Cardiovascular Risk
Status: RECRUITING
Conditions: Hypertension
Interventions: DRUG: VB0004|OTHER: Matching Placebo for VB0004
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Cardiovascular Outcomes in Patients With Type 2 Diabetes After Acute Coronary Syndrome During Treatment With AVE0010 (Lixisenatide)
Status: COMPLETED
Conditions: Acute Coronary Syndrome
Interventions: DRUG: Lixisenatide (AVE0010)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MAPLES Pilot Study for Low Mood in ABI
Status: COMPLETED
Conditions: Acquired Brain Injury|Depression
Interventions: BEHAVIORAL: Activity Planning Group|BEHAVIORAL: Activity Engagement Group|BEHAVIORAL: Waitlist Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Telemedicine for Women With Anhedonia in Bipolar and Unipolar Disorder
Status: COMPLETED
Conditions: Depression|Bipolar Disorder|Anhedonia
Interventions: BEHAVIORAL: Behavioral Activation-Full|BEHAVIORAL: Behavioral Activation-Short|BEHAVIORAL: Bipolar Disorder Collaborative Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessing the Effects of Cool Roofs on Indoor Environments and Health: a Global Multi-center Study
Status: NOT_YET_RECRUITING
Conditions: Resting Heart Rate|Blood Glucose Control|Depression|Heat-related Symptoms|Physician Diagnosed Heat-related Illnesses|Food Insecurity|Diet Quality|Health-related Quality of Life|Indoor Thermal Comfort|Coping Ability|Life Satisfaction|Healthcare Provider Utilization|Hospitalization|Systolic Blood Pressure|Diastolic Blood Pressure|Inner Ear Canal Temperature|Dehydration|Sleep Quality|Cognition|Productivity|Aggression|Indoor Air Temperature|Indoor Relative Humidity|Indoor Heat Index|Household Energy Expenditure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of ACC Inhibitor on Lipid and Lipoprotein Metabolism
Status: WITHDRAWN
Conditions: NASH (Nonalcoholic Steatohepatitis)|NAFLD (Nonalcoholic Fatty Liver Disease)
Interventions: DRUG: PF-05221304|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Success of Paravertebral Blocks in Analgesia for Interventional Hepatic Procedures
Status: WITHDRAWN
Conditions: Liver Neoplasms
Interventions: PROCEDURE: Paravertebral block|PROCEDURE: Control sham procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Characterization of Circulating Tumor Cells Captured by c-MET (CTC-MET)
Status: COMPLETED
Conditions: Prostate Cancer|Renal Cell Carcinoma|Bladder Cancer|Colorectal Cancer|Gastric Cancer|Pancreatic Cancer|Non-small Cell Lung Cancer|Advanced MET Amplified Solid Tumor
Interventions: DEVICE: Mesenchymal-marker based ferrofluid (c-MET)|DEVICE: Epithelial cell adhesion molecule (EpCAM) ferrofluid
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: DARA RVD For High Risk SMM
Status: RECRUITING
Conditions: High-risk Smoldering Multiple Myeloma|Multiple Myeloma
Interventions: DRUG: Daratumumab|DRUG: Bortezomib|DRUG: Lenalidomide|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of Three Different Techniques Restoring Ellis Class II Traumatized Central Incisors In Children
Status: NOT_YET_RECRUITING
Conditions: Composites Resins
Interventions: OTHER: IPS e.max CAD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Prospective, Single-arm, Clinical Trial of Electrospun Fiber Matrix (Restrata) in the Treatment of Surgical Defects Secondary to Resection of Malignant Cutaneous Neoplasms
Status: NOT_YET_RECRUITING
Conditions: Surgical Wound
Interventions: DEVICE: Synthetic Electrospun Fiber Matrix
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Immunogenicity of Influenza Vaccine (Surface Antigen, Inactivated) Ph.Eur, Formulation 2008-2009, When Administered to Non-Elderly Adult and Elderly Subjects
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Flu Vaccine Influenza Vaccine (Surface Antigen, Inactivated) Ph.Eur, Formulation 2008-2009
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: TMC114-C209: A Study of Safety of TMC114 With Low Dose Ritonavir (RTV) and Other Antiretrovirals in Experienced HIV-1 Infected Patients With Limited or no Treatment Options
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: TMC114
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sonolysis in Risk Reduction of Symptomatic and Silent Brain Infarctions During Coronary Stenting
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DEVICE: Sonolysis|OTHER: Sham procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Antibiotics for Klebsiella Liver Abscess Study
Status: COMPLETED
Conditions: Liver Abscess, Pyogenic
Interventions: DRUG: Ciprofloxacin|DRUG: Ceftriaxone|DRUG: Trimethoprim/sulfamethoxazole|DRUG: Ertapenem
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT