pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Stereotactic Body Radiation Therapy After Surgery in Treating Patients With Stage III-IV Non-small Cell Lung Cancer
Status: COMPLETED
Conditions: Recurrent Non-small Cell Lung Cancer|Stage IIIA Non-small Cell Lung Cancer|Stage IIIB Non-small Cell Lung Cancer|Stage IV Non-small Cell Lung Cancer
Interventions: COMBINATION_PRODUCT: therapeutic lymphadenectomy (TEMLA) and Stereotactic Body radiation therapy (SBRT)|OTHER: quality-of-life assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigation of Subclinical Markers of Multiple Sclerosis
Status: RECRUITING
Conditions: Multiple Sclerosis|Relapsing Remitting Multiple Sclerosis
Interventions: DIAGNOSTIC_TEST: 1. Clinical testing; 2. Neurophysiological examination (TMS, EMNG); 3. Psychomotor examination; 4. Neuropsychological evaluation; 5. Flow cytometry; 6. ELISA
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Insulin Deprivation on Brain Structure and Function in Humans With Type 1 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1|Diabetes|Diabetes Complications
Interventions: OTHER: Insulin Deprivation in Type 1 Diabetic Patients
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Different Protein Diets on Glucose and Insulin Metabolism and Substrate Partitioning
Status: COMPLETED
Conditions: Insulin|Glucose Metabolism
Interventions: DIETARY_SUPPLEMENT: Control|DIETARY_SUPPLEMENT: High dairy protein|DIETARY_SUPPLEMENT: vegetable protein|DIETARY_SUPPLEMENT: High GI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Study of Acute Myocardial Infarction Using FDY-5301
Status: COMPLETED
Conditions: Acute Myocardial Infarction|STEMI
Interventions: DRUG: FDY-5301|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Evaluation of a Web-based Platform for Osteoarthritis Treatment
Status: SUSPENDED
Conditions: Osteoarthritis, Knee
Interventions: BEHAVIORAL: Online Osteoarthritis treatment|BEHAVIORAL: Face-to-face osteoarthritis treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Effects of Myofascial Induction Therapy Versus Gastrocnemius Pressure Release Treatment on Trigger Point Pressure Pain Threshold in Proximal Muscles and Ankle Range of Motion.
Status: COMPLETED
Conditions: Pain Threshold|Myofascial Trigger Point|Manual Therapy|Range of Motion
Interventions: OTHER: Myofascial induction in gastrocnemius|OTHER: Preassure release
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ADJUNCTIVE EFFECT OF LIGHT EMITTING DIODE ON HAND GRIP STRENGTH IN BURN PATIENTS
Status: UNKNOWN
Conditions: Burns|Hand Burn|Hand Grasp|Hand Injuries
Interventions: DEVICE: Light emitting diode therapy (LED therapy)|BEHAVIORAL: Patient/family education program (Home program)|PROCEDURE: Positioning & Splinting|OTHER: Therapeutic Exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Antimicrobial Photodynamic Therapy in Patients With Periodontal Disease and Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Periodontal Diseases|Diabetes Mellitus, Type 2|Periodontitis|Periodontal Pocket|Periodontal Attachment Loss|Periodontal Inflammation
Interventions: PROCEDURE: Conventional Periodontal Treatment (Complete Oral Disinfection)|PROCEDURE: Adjunctive Photodynamic Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Adjuvant Gemcitabine Started One Week After Laparoscopic Distal Pancreatectomy for Adenocarcinoma
Status: WITHDRAWN
Conditions: Pancreatic Neoplasms
Interventions: DRUG: Gemcitabine/Gemzar|PROCEDURE: Laparoscopic Distal pancreatectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Supporting Health Behavior Among Persons Living With HIV Using Tech, MOST, and Behavioral Economics
Status: COMPLETED
Conditions: HIV Seropositivity|Adherence, Medication
Interventions: BEHAVIORAL: MI sessions|BEHAVIORAL: TMQQ|BEHAVIORAL: Type of compensation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Triamcinolone -Acetonide Therapy for the Treatment of the Medial Plica Syndrome
Status: RECRUITING
Conditions: Medial Plica Syndrome
Interventions: PROCEDURE: Eco-guided Triamcinolone-Acetonide injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of a Meal Replacement on Weight Loss Obesity Patients With Metabolic Syndrome
Status: UNKNOWN
Conditions: Abdominal Obesity-Metabolic Syndrome
Interventions: DIETARY_SUPPLEMENT: meal replacement group|BEHAVIORAL: control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vaginal Misoprostol for Cervical Ripening Prior to Endometrial Biopsy
Status: WITHDRAWN
Conditions: Menorrhagia|Endometrial Biopsy|Cervical Ripening
Interventions: DRUG: Misoprostol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Autologous Rectus Sheath Fascia Versus Midurethral Transobturator Tension Free Vaginal
Status: UNKNOWN
Conditions: Stress Urinary Incontinence
Interventions: PROCEDURE: Hybrid sling|PROCEDURE: TVT-O
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Carfilzomib, Cyclophosphamide and Dexamethasone in Newly Diagnosed Multiple Myeloma Patients
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Carfilzomib|DRUG: Cyclophosphamide|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A First-in-human Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of HM15211
Status: COMPLETED
Conditions: Obesity
Interventions: BIOLOGICAL: HM15211 or Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Tazemetostat in Combination With Doxorubicin as Frontline Therapy for Advanced Epithelioid Sarcoma
Status: RECRUITING
Conditions: Advanced Soft-tissue Sarcoma|Advanced Epithelioid Sarcoma
Interventions: DRUG: Tazemetostat|DRUG: Doxorubicin HCl|DRUG: Tazemetostat|DRUG: Placebo|DRUG: Doxorubicin HCl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Vitamin D Dose-Response Relationship
Status: COMPLETED
Conditions: Vitamin D Status
Interventions: RADIATION: UVB|RADIATION: UVB|RADIATION: UVB|RADIATION: UVB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Diphenhydramine for Acute Migraine
Status: COMPLETED
Conditions: Migraine
Interventions: DRUG: metoclopramide|DRUG: diphenhydramine|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of The Safety, Efficacy and Pharmacokinetic Characteristics of GST-HG141 Tablets
Status: RECRUITING
Conditions: Chronic Hepatitis b
Interventions: DRUG: GST-HG141
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a New Catheter Coating Process for Urinary Catheters Used for Intermittent Catheterization.
Status: COMPLETED
Conditions: Intermittent Urethral Catheterization
Interventions: DEVICE: Treatment Period One|DEVICE: Treatment Period Two
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Overcome Biochemical Aspirin Resistance Through Cilostazol Combination
Status: COMPLETED
Conditions: Cerebral Infarction
Interventions: DRUG: Cilostazol|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the SafeSeal(TM) Hemostasis Patch Following Percutaneous Coronary Artery and Peripheral Vascular Interventions
Status: COMPLETED
Conditions: Coronary Artery Disease|Peripheral Vascular Disease
Interventions: DEVICE: SafeSeal(TM) Hemostasis Patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot- and Feasibility Trial of the eHealth Tool My COPD for People With COPD
Status: UNKNOWN
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DEVICE: My COPD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Capecitabine and Oxaliplatin Plus Bevacizumab as Neoadjuvant Treatment for Untreated Unresectable Liver-only Metastases From Colorectal Cancer
Status: COMPLETED
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: Capecitabine|DRUG: Oxaliplatin|DRUG: Bevacizumab|PROCEDURE: Liver metastasectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tenaculum Pain Control Study
Status: COMPLETED
Conditions: Cervical Pain|Pelvic Pain
Interventions: DRUG: Intracervical Lidocaine Injection|DRUG: Topical Lidocaine Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Evaluate the Safety/Tolerability and Pharmacokinetics of Aliskiren in Hypertensive Pediatric and Adolescent Patients 6-17 Years of Age
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Aliskiren 3.125 mini-tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RAMBAM 021: Safety and Initial Feasibility of the Neurolyser XR for the Treatment of Chronic Low Back Pain
Status: COMPLETED
Conditions: Facet Syndrome of Lumbar Spine
Interventions: DEVICE: Non-Invasive Thermal Ablation of the Medial Branch Nerves using the Neurolyser XR
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pure Fish Oil Parenteral Lipid Emulsion in Patients With Gastrointestinal Cancer
Status: COMPLETED
Conditions: Surgery
Interventions: DIETARY_SUPPLEMENT: Fish oil lipid emulsion|DIETARY_SUPPLEMENT: MCT/LCT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Determine the Effect of Nitroglycerin Ointment 0.4% (Cellegesic) on the Pain Associated With Chronic Anal Fissures
Status: COMPLETED
Conditions: Fissure in Ano|Pain
Interventions: DRUG: Cellegesic|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Subjects Treated With rhuMab 2C4 (Pertuzumab) in a Previous Genentech Phase II Cancer Study
Status: COMPLETED
Conditions: Solid Cancers
Interventions: DRUG: Pertuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Characterize Pharmacokinetics (PK) and Pharmacodynamics (PD) of LUSEDRA® Administered as Continuous Infusion or Bolus Compared With Continuous Infusion of Propofol Injectable Emulsion
Status: COMPLETED
Conditions: Monitored Anesthesia Care
Interventions: DRUG: arm 1|DRUG: LUSEDRA|DRUG: Propofol (arm 3)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Internal Limiting Membrane Peeling on Visual Function in Epiretinal Membrane Surgery
Status: UNKNOWN
Conditions: Retinal Disease|Epiretinal Membrane
Interventions: PROCEDURE: Internal Limiting Membrane Peeling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Proof of Concept Study of Latanoprost/Minoxidil (ANR-001.1) Topical Formulation
Status: RECRUITING
Conditions: Hypotrichosis
Interventions: COMBINATION_PRODUCT: Latanoprost and Minoxidil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effects of Chocolate in Patients With Chronic Heart Failure
Status: COMPLETED
Conditions: Heart Failure
Interventions: DIETARY_SUPPLEMENT: Nestlé Noir intense 40 grx2|DIETARY_SUPPLEMENT: Nestlé Placebo Chocolate 40 grx2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ovulation Induction in Women With Clomiphene Citrate Resistant PCOS
Status: COMPLETED
Conditions: Polycystic Ovary Syndrome|Infertility
Interventions: DRUG: induction of ovulation using letrozole-pioglitazone-metformin|DRUG: induction of ovulation using clomiphene citrate-pioglitazone-metformin|RADIATION: transvaginal ultrasound|OTHER: body mass index (BMI) calculation|OTHER: day 3: follicle stimulating hormone (FSH), luteinizing hormone (LH), thyroid stimulating hormone (TSH), total testosterone|OTHER: pretreatment blood urea and serum creatinine|OTHER: serum estradiol (E2) on day 12|OTHER: serum progesterone on day 21|OTHER: blood urea and serum creatinine every month
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability Study of Levetiracetam to Treat Patients With Status Epilepticus
Status: UNKNOWN
Conditions: Status Epilepticus
Interventions: DRUG: levetiracetam (add-on)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Postoperative Chemoradiation or Chemotherapy After Preoperative Chemotherapy for Gastric Cancers
Status: TERMINATED
Conditions: Gastrointestinal Cancer
Interventions: DRUG: Oxaliplatin|DRUG: Capecitabine|DRUG: Leucovorin|DRUG: 5-fluorouracil|RADIATION: radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Oxygen During Percutaneous Coronary Intervention for Pain Relief
Status: COMPLETED
Conditions: Angina
Interventions: DRUG: Nasal oxygen|DRUG: Regular nasal air
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase IIa Study of Fomepizole for Acetaldehyde Toxicity After Ethanol Exposure in Subjects With Altered Ethanol Metabolism
Status: COMPLETED
Conditions: Aldehyde Dehydrogenase-2 (ALDH2) Deficiency
Interventions: DRUG: Antizol|DRUG: Placebo|OTHER: Ethanol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of AVE0005 (VEGF Trap) in Locally Advanced or Metastatic Platinum- and Erlotinib- Resistant Non-small-cell-lung Adenocarcinoma
Status: COMPLETED
Conditions: Pulmonary Diseases|Neoplasms, Lung
Interventions: DRUG: Aflibercept (ziv-aflibercept, AVE0005, VEGF trap, ZALTRAP®)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Overnight Pant Study for Children With Nocturnal Enuresis
Status: COMPLETED
Conditions: Nocturnal Enuresis
Interventions: DEVICE: Ninjamas Pyjama Pants|OTHER: Participant's Overnight Current Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Dehydroepiandrosterone Substitution in Adolescent and Young Women With Central Adrenal Insufficiency
Status: COMPLETED
Conditions: Adrenal Insufficiency
Interventions: DRUG: Dehydroepiandrosterone|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: My Pathway: A Study Evaluating Herceptin/Perjeta, Tarceva, Zelboraf/Cotellic, Erivedge, Alecensa, and Tecentriq Treatment Targeted Against Certain Molecular Alterations in Participants With Advanced Solid Tumors
Status: COMPLETED
Conditions: Neoplasms|Solid Tumors|Biliary Cancer|Salivary Cancer|Bladder Cancer
Interventions: DRUG: Trastuzumab|DRUG: Pertuzumab|DRUG: Erlotinib|DRUG: Vemurafenib|DRUG: Cobimetinib|DRUG: Vismodegib|DRUG: Alectinib|DRUG: Atezolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of High-intensity Laser Therapy in Patients With Chronic Shoulder Pain
Status: COMPLETED
Conditions: Chronic Shoulder Pain
Interventions: OTHER: Conventional physiotherapy|DEVICE: High-intensity laser therapy (HILT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Docetaxel for Injection (Albumin Bound) in Patients With Advanced Pancreatic Cancer
Status: NOT_YET_RECRUITING
Conditions: Advanced Pancreatic Cancer
Interventions: DRUG: Docetaxel for Injection (Albumin bound)|DRUG: Placebo|DRUG: Best supportive care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Open-label Study of the Efficacy and Safety of VESIcare® in Patients With Overactive Bladder Symptoms
Status: COMPLETED
Conditions: Urinary Bladder, Overactive
Interventions: DRUG: solifenacin succinate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility Study of ABC for Women Treated for Breast Cancer
Status: NOT_YET_RECRUITING
Conditions: Breast Cancer Female
Interventions: BEHAVIORAL: Accepting your Body after Cancer|BEHAVIORAL: Macmillan body image booklet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Workplace Interventions Preventing Risky Use of Alcohol and Sick Leave
Status: ACTIVE_NOT_RECRUITING
Conditions: Alcohol Consumption|Sick Leave|Workplace Interventions|Presenteeism
Interventions: BEHAVIORAL: Riskbruk|BEHAVIORAL: Balance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Treatment of Newly Diagnosed Rhabdomyosarcoma Using Molecular Risk Stratification and Liposomal Irinotecan Based Therapy in Children With Intermediate and High Risk Disease
Status: RECRUITING
Conditions: Rhabdomyosarcoma
Interventions: DRUG: Vincristine|DRUG: Dactinomycin|DRUG: Cyclophosphamide|PROCEDURE: Surgical Resection|PROCEDURE: Proton beam radiation or external beam radiation or brachytherapy|DRUG: Liposomal irinotecan|DRUG: Vinorelbine|DRUG: Temozolomide|DRUG: Filgrastim, peg-filgrastim
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Potassium Lowering Drugs on Cardiac Electrical Stability in Hemodialysis Patients (ART Study)
Status: RECRUITING
Conditions: Potassium Imbalance|Cardiac Arrhythmia|Dialysis; Complications
Interventions: DRUG: sodium zirconium cyclic silicate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Markers to Evaluate the Efficacy of PH-based Regimen as a Neoadjuvant Therapy for Operable HER2 Positive Breast Cancer
Status: RECRUITING
Conditions: HER2-positive Breast Cancer
Interventions: DIAGNOSTIC_TEST: TCHP
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effectiveness of Khat on Eyelid Wound Healing After Oculoplastic Surgery - a Prospective Study.
Status: UNKNOWN
Conditions: Hematoma|Surgical Wound|Surgery|Eye Bruise|Edema
Interventions: BIOLOGICAL: Khat leaves
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Efficacy and Safety Study of Anti-TNF Monoclonal Antibody in Patients With Fistulizing Crohn's Disease
Status: COMPLETED
Conditions: Crohn Disease
Interventions: DRUG: Infliximab 10 mg/kg|DRUG: Infliximab 5 mg/kg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Intralesional Triamcinolone Injection in the Treatment of Vitiligo
Status: UNKNOWN
Conditions: Vitiligo|Treatment|Intralesional Injection|Corticosteroid
Interventions: DRUG: Triamcinolone acetonide 0.4mg/cc|DEVICE: Phototherapy (NBUVB or excimer laser)|DRUG: Topical tacrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: School-Based Depression Prevention for Adolescents With ADHD
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder|Depressive Symptoms
Interventions: BEHAVIORAL: Behaviorally Enhancing Adolescents' Mood in Schools|BEHAVIORAL: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: An Idiographic Examination of Treatment Mechanisms in Emotion Regulation Therapy
Status: ACTIVE_NOT_RECRUITING
Conditions: Rumination|Worry|Self-Criticism|Anxiety|Depression|Distress, Emotional
Interventions: BEHAVIORAL: Emotion Regulation Therapy via Telehealth
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Erlotinib in Combination With Docetaxel in Advanced Hepatocellular and Biliary Tract Carcinomas
Status: TERMINATED
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Erlotinib|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Arthrodesis Versus Extra-articular Plate Fixation in Lisfranc Injury
Status: COMPLETED
Conditions: Lisfranc Injuries
Interventions: PROCEDURE: Temporary extraarticular plate fixation|PROCEDURE: Primary arthrodesis|PROCEDURE: Primary arthrodesis TMT 2 and 3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neurocognitive Factors in Substance Use Treatment Response: The Ways of Rewarding Abstinence Project
Status: ACTIVE_NOT_RECRUITING
Conditions: Cocaine Use Disorder
Interventions: BEHAVIORAL: Prize-Based Contingency Management|BEHAVIORAL: Treatment As Usual Outpatient Substance Use Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: STUDY OF SURVIVAL AND FUNCTIONALITY IN CRYOPRESERVED PLATELETS
Status: UNKNOWN
Conditions: Platelet Cryopreservation|Platelet Survival
Interventions: OTHER: platelet cryopreservation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of External Ear Stimulation on Pain Perception and Mood
Status: RECRUITING
Conditions: Pain in Healthy Participants
Interventions: DEVICE: The Twin Stim Plus, 3rd Edition|DEVICE: Medoc Pathway System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: rhPSMA-73 PET-MRI Imaging for the Detection of Prostate Cancer Among Men Who Are Otherwise Candidates for Active Surveillance
Status: RECRUITING
Conditions: Prostate Adenocarcinoma|Stage I Prostate Cancer AJCC v8|Stage IIA Prostate Cancer AJCC v8|Stage IIB Prostate Cancer AJCC v8
Interventions: PROCEDURE: Biopsy of Prostate|GENETIC: Decipher Prostate Cancer Test|OTHER: Flotufolastat F-18 Gallium|PROCEDURE: Magnetic Resonance Imaging|PROCEDURE: Multiparametric Magnetic Resonance Imaging|PROCEDURE: Positron Emission Tomography|PROCEDURE: Radical Prostatectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effect of Stress, Anxiety, and Depression Experienced by Pregnant Women on Sleep Bruxism and Oral Health
Status: COMPLETED
Conditions: Sleep Bruxism, Adult|Stress|Depression|Anxiety|Pregnancy Related|Oral Disease
Interventions: OTHER: Pregnant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Respiratory Rehabilitation in Obstructive Sleep Apneas
Status: COMPLETED
Conditions: Sleep Disorder|Sleep Apnea Syndromes
Interventions: BEHAVIORAL: Myofunctional exercises|BEHAVIORAL: The rules of sleep hygiene
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: PTCCO2 Monitoring During Retroperitoneoscopic Urologic Surgery
Status: COMPLETED
Conditions: Transcutaneous Carbon Dioxide Partial Pressure Monitoring|Retroperitoneoscopic Urologic Surgery
Interventions: DEVICE: transcutaneous monitor (TCM-4 monitor)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of Low-Dose, Standard-Dose Ticagrelor and Clopidogrel for Inhibition of Platelet Reactivity in Patients With Acute Coronary Syndromes
Status: COMPLETED
Conditions: Acute Coronary Syndrome
Interventions: DRUG: ticagrelor|DRUG: clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fasting Study of Quinapril HCl and Hydrochlorothiazide Tablets 20 mg/25 mg to Accuretic™ Tablets 20 mg/25 mg
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Quinapril HCl and Hydrochlorothiazide Tablets 20 mg/25 mg|DRUG: Accuretic™ Tablets 20 mg/25 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: IGF-1 Therapy in Patients With Cystic Fibrosis
Status: TERMINATED
Conditions: Cystic Fibrosis
Interventions: DRUG: recombinant human IGF-1|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ondansetron and Gabapentin in Preventing Postoperative Nausea and Vomiting After Laparoscopic Sleeve Gastrectomy
Status: RECRUITING
Conditions: Post Operative Nausea and Vomiting|Sleeve Gastrectomy|Morbid Obesity
Interventions: DRUG: Ondansetron 8mg|DRUG: Gabapentin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Cabergoline As An Adjuvant To Clomiphene Citrate For Management Of Unexplained Infertility
Status: UNKNOWN
Conditions: Infertility
Interventions: DRUG: Clomiphene Citrate 50mg|DRUG: Cabergoline Oral Tablet|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Safety and Effectiveness of OBG vs.a Bandage Contact Lens for Large Corneal Epithelial Defects in Patients Post-PRK.
Status: COMPLETED
Conditions: Corneal Epithelial Wound
Interventions: DEVICE: Acuvue Oasys|DEVICE: Ocular Bandage Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Epoetin Alfa in Treating Anemia in Patients With Lymphoma, Chronic Lymphocytic Leukemia, or Multiple Myeloma and Anemia Caused By Chemotherapy
Status: COMPLETED
Conditions: Anemia|Leukemia|Lymphoma|Multiple Myeloma and Plasma Cell Neoplasm
Interventions: BIOLOGICAL: epoetin alfa|PROCEDURE: quality-of-life assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Adjuvant Chemotherapy vs. Observation/Mitotane After Primary Surgical Resection of Localized Adrenocortical CarcInoma
Status: COMPLETED
Conditions: Adrenocortical Carcinoma
Interventions: DRUG: Cisplatin plus Etoposide|OTHER: Observation or Mitotane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Saracatinib and Paclitaxel in Platinum-resistant Ovarian Cancer
Status: COMPLETED
Conditions: Ovarian Cancer|Fallopian Tube Cancer|Primary Peritoneal Cancer
Interventions: DRUG: Paclitaxel|DRUG: Saracatinib|DRUG: Matched placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial on Ophthalmologist-delivered Health Education on Top of Routine Community Care
Status: RECRUITING
Conditions: Diabetes Mellitus, Type 2
Interventions: OTHER: Ophthalmologist-delivered health education|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate Patient Experience in the Therapy of Neuroendocrine Tumors Treated With Octreotide Long Acting Release Versus Lanreotide
Status: COMPLETED
Conditions: Neuroendocrine Tumors
Interventions: DRUG: Octreotide|DRUG: LAR Lanreotide|BEHAVIORAL: Questionnaires
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Real World Study of Pyrotinib in the Treatment of Advanced Breast Cancer With HER2 Positive
Status: NOT_YET_RECRUITING
Conditions: Breast Cancer|RWS|Pyrotinib
Interventions: DRUG: Pyrotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reducing Delirium After Cardiac Surgery: A Multifaceted Approach Of Perioperative Care
Status: COMPLETED
Conditions: Delirium|Cardiac Disease
Interventions: DRUG: Propofol|DRUG: Dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Analgesic Efficacy of Transcutaneous Electrical Nerve Stimulation (TENS) Versus Placebo During the First Stage of Labor
Status: UNKNOWN
Conditions: Transcutaneous Electric Nerve Stimulation|Labor Pain
Interventions: DEVICE: TENS|DEVICE: TENS Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: An Dose Escalation Study of BIBF 1120 Administered in Patients With Relapsed or Refractory Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: BIBF 1120 ES
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Acarbose and Vildagliptin on Visceral Fat Distribution in Newly Diagnosed Type 2 Diabetes Patients
Status: UNKNOWN
Conditions: Diabetes Mellitus, Type 2|Obesity
Interventions: DRUG: Acarbose|DRUG: Vildagliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ED50 and ED95 of Intrathecal Hyperbaric Bupivacaine With Fentanyl for Transurethral Prostatectomy in Elderly Patients
Status: COMPLETED
Conditions: Old Age
Interventions: DRUG: Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intensive Consolidation and Stem Cell Mobilization Therapy Followed by Autologous Stem Cell Transplantation in High-risk Patients With Relapsed/Refractory Diffuse Large B-Cell Lymphoma
Status: COMPLETED
Conditions: Diffuse Large Cell Lymphoma Relapsed/Refractory
Interventions: DRUG: Ofatumumab|DRUG: Etoposide|DRUG: Cytarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TTI-622 and TTI-621 in Combination With Pembrolizumab for the Treatment of Relapsed or Refractory Diffuse Large B-Cell Lymphoma
Status: RECRUITING
Conditions: Recurrent ALK Positive Large B-Cell Lymphoma|Recurrent B-Cell Non-Hodgkin Lymphoma|Recurrent Diffuse Large B-Cell Lymphoma Associated With Chronic Inflammation|Recurrent Diffuse Large B-Cell Lymphoma, Not Otherwise Specified|Recurrent EBV-Positive Diffuse Large B-Cell Lymphoma, Not Otherwise Specified|Recurrent Grade 3b Follicular Lymphoma|Recurrent High Grade B-Cell Lymphoma|Recurrent High Grade B-Cell Lymphoma With MYC and BCL2 or BCL6 Rearrangements|Recurrent High Grade B-Cell Lymphoma With MYC, BCL2, and BCL6 Rearrangements|Recurrent High Grade B-Cell Lymphoma, Not Otherwise Specified|Recurrent Intravascular Large B-Cell Lymphoma|Recurrent Primary Cutaneous Diffuse Large B-Cell Lymphoma, Leg Type|Recurrent Primary Mediastinal (Thymic) Large B-Cell Lymphoma|Recurrent T-Cell/Histiocyte-Rich Large B-Cell Lymphoma|Refractory ALK Positive Large B-Cell Lymphoma|Refractory Diffuse Large B-Cell Lymphoma Associated With Chronic Inflammation|Refractory Diffuse Large B-Cell Lymphoma, Not Otherwise Specified|Refractory EBV-Positive Diffuse Large B-Cell Lymphoma, Not Otherwise Specified|Refractory Grade 3b Follicular Lymphoma|Refractory High Grade B-Cell Lymphoma|Refractory High Grade B-Cell Lymphoma With MYC and BCL2 or BCL6 Rearrangements|Refractory High Grade B-Cell Lymphoma With MYC, BCL2, and BCL6 Rearrangements|Refractory High Grade B-Cell Lymphoma, Not Otherwise Specified|Refractory Intravascular Large B-Cell Lymphoma|Refractory Primary Cutaneous Diffuse Large B-Cell Lymphoma, Leg Type|Refractory Primary Mediastinal Large B-Cell Lymphoma|Refractory T-Cell/Histiocyte-Rich Large B-Cell Lymphoma|Recurrent Gray Zone Lymphoma
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|DRUG: Ontorpacept|BIOLOGICAL: Pembrolizumab|PROCEDURE: Positron Emission Tomography|DRUG: Maplirpacept
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Usability of a Multimodal External Neuromodulatory Device to Relieve Acute Low Back Pain
Status: COMPLETED
Conditions: Low Back Pain|Low Back Sprain|Low Back Pain, Recurrent
Interventions: DEVICE: Duotherm VibraCool Back Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Effect of Midazolam Premedication on Mask Ventilation Difficulty
Status: COMPLETED
Conditions: Anesthesia Complication
Interventions: DRUG: Midazolam|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Single-use Cystoscope System for Direct Visualization of the Urethra and Bladder
Status: COMPLETED
Conditions: Cystoscope|Bladder Cancer|Lower Urinary Tract Symptoms
Interventions: DEVICE: Ambu aScope 4 Cysto and aView Urologia
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Assessing the Clinical Performance of Two Frequent Replacement Silicone Hydrogel Multifocal Contact Lenses
Status: COMPLETED
Conditions: Presbyopia
Interventions: DEVICE: Lehfilcon A multifocal contact lenses|DEVICE: Lotrafilcon B multifocal contact lenses|DEVICE: Hydrogen peroxide-based cleaning and disinfection system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Topical MTS-01 for Dermatitis During Radiation and Chemotherapy for Anal Cancer
Status: TERMINATED
Conditions: Anal Cancer
Interventions: DRUG: Tempol|DRUG: 5-Fluorouracil|DRUG: Mitomycin-C|PROCEDURE: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prognostic and Diagnostic Added Value of Medical Imaging in Gynecological Cancer (PRODIGYN)
Status: RECRUITING
Conditions: Cervix Cancer|Endometrial Cancer|Epithelial Ovarian Cancer
Interventions: DIAGNOSTIC_TEST: FDG-PET/CT and FDG-PET/MRI
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: MOlecular BIomarkers and Adherent and Invasive Escherichia Coli (AIEC) Detection Study In Crohn's Disease Patients
Status: TERMINATED
Conditions: Crohn's Disease
Interventions: OTHER: Biopsies, stool and blood collection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Using Gum Arabic for Cancer Patients to Protect From Oral Mucositis Caused by Chemotherapy: ِِِAn Experimental Study
Status: COMPLETED
Conditions: Chemotherapy-induced Oral Mucositis
Interventions: DRUG: Gum Arabic|DRUG: Chemotherapy|BEHAVIORAL: Lifestyle counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Virtual Reality as a Treatment Tool for Chronic Neck Pain in Patients With Fibromyalgia
Status: NOT_YET_RECRUITING
Conditions: Fibromyalgia
Interventions: OTHER: Virtual reality|OTHER: Exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Apatinib Combined With S-1 as Maintenance Therapy for HER-2 Negatived Gastric Cancer
Status: UNKNOWN
Conditions: HER-2 Negatived Gastric Cancer
Interventions: DRUG: Apatinib and S-1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EBV-Tscm Cytotoxic T Cells (CTLs) for EBV- Driven Lymphomas/ Diseases
Status: NOT_YET_RECRUITING
Conditions: EBV Lymphoma|Post-transplant Lymphoproliferative Disease (PTLD)
Interventions: DRUG: Donor-derived ex-vivo expanded EBV Tscm CTL
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Two In-hospital Antepartum Interventions on Functional Ability and Quality of Life in Early Postpartum Women.
Status: COMPLETED
Conditions: High-Risk Pregnancy
Interventions: OTHER: Music Intervention|OTHER: Muscle Conditioning Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Feasibility of Screening Relatives of Patients Affected by Non-Syndromic Thoracic Aortic Diseases
Status: UNKNOWN
Conditions: Screening|Aortic Aneurysm and Dissection|Genetic Disease
Interventions: GENETIC: WES|DIAGNOSTIC_TEST: MRI|DIAGNOSTIC_TEST: TTE|OTHER: Questionnaire
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study to Compare the Safety and Efficacy of Solifenacin With Oxybutynin for the Treatment of Overactive Bladder (VECTOR)
Status: COMPLETED
Conditions: Overactive Bladder
Interventions: DRUG: solifenacin|DRUG: oxybutynin immediate release
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cluster-randomized Trial Measuring Integration of Professional Midwives and Obstetric Nurses in Rural Clinics in Mexico
Status: COMPLETED
Conditions: Pregnancy
Interventions: OTHER: PM/ON integration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Inhibition of the Endogenous GIP Response With a GIP Receptor Antagonist
Status: COMPLETED
Conditions: Glucose Metabolism Disorders
Interventions: OTHER: GIP-A|OTHER: GLP-1 receptor antagonist Exendin[9-39]|OTHER: Placebo|OTHER: GIP-A + Exendin[9-39]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Povidone Iodine Irrıgation at Hip-Knee Arthroplasty
Status: RECRUITING
Conditions: Osteoarthritis|Hyperthyroidism|Iodine Toxicity
Interventions: PROCEDURE: PI solution|PROCEDURE: Saline Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SCREENING
Clinical trial: Pralatrexate and Bexarotene in Patients With Relapsed or Refractory Cutaneous T-cell Lymphoma
Status: COMPLETED
Conditions: Cutaneous T-cell Lymphoma|Mycosis Fungoides|Sezary Syndrome|Primary Cutaneous Anaplastic Large Cell Lymphoma
Interventions: DRUG: Pralatrexate Injection|DRUG: Bexarotene Capsules|DIETARY_SUPPLEMENT: Vitamin B12|DIETARY_SUPPLEMENT: Folic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Precision Event Monitoring for Patients With Heart Failure Using HeartLogic
Status: COMPLETED
Conditions: Heart Failure|Defibrillators, Implantable|Monitoring, Physiologic|Cardiac Resynchronization Therapy|Cardiovascular Disease|Heart Disease
Interventions: DEVICE: HeartLogic Sensors
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: RE-inventing Strategies for Healthy Ageing; Recommendations and Tools
Status: ACTIVE_NOT_RECRUITING
Conditions: Lifestyle, Healthy|Muscle Weakness|Abdominal Obesity|Cardiometabolic Syndrome|Self Efficacy|Diet, Healthy
Interventions: BEHAVIORAL: Complex lifestyle intervention|BEHAVIORAL: Physical activity monitoring and recommendations
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: BGJ398 in Combination With Imatinib Mesylate in Patients With Untreated Advanced Gastrointestinal Stromal Tumor (GIST)
Status: COMPLETED
Conditions: Advanced Gastrointestinal Stromal Tumor (GIST)
Interventions: DRUG: BGJ398|DRUG: Imatinib Mesylate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Electroacupuncture on the Incidence of Postoperative Delirium in Elderly Patients Undergoing the Major Surgery
Status: COMPLETED
Conditions: Postoperative Delirium
Interventions: DEVICE: electroacupuncture treatment|DEVICE: sham electroacupuncture treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Comparative Study Between Different Volumes During Erector Spinae Block for Pain Control
Status: COMPLETED
Conditions: Postoperative Pain Management
Interventions: PROCEDURE: erector spinae block by 0.25% bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Role of TAP and RS Block in Reduction of Postoperative Pain for Gynecological Surgical Laparoscopic Procedures
Status: UNKNOWN
Conditions: TAP and RS Block
Interventions: PROCEDURE: TAP block and RS block + General Intravenous Anesthestic|DRUG: General Intravenous Anesthetic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Similarities and Differences of Biological Therapies for Severe Asthma.
Status: UNKNOWN
Conditions: Asthma
Interventions: BIOLOGICAL: Mepolizumab|BIOLOGICAL: Omalizumab|BIOLOGICAL: Reslizumab|BIOLOGICAL: Benralizumab|BIOLOGICAL: Dupilumab
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Implementation of a Non-invasive Version of the Imaging β-adrenergic-dependent Sweat Secretion Test
Status: UNKNOWN
Conditions: Mucoviscidosis Involving the Lung
Interventions: DIAGNOSTIC_TEST: Iontophoresis sessions in forearm of subjects with pilocarpine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy of Omega-3 as Adjunctive Therapy for Medically Intractable Epilepsy: A Prospective Open-label Pilot Study
Status: UNKNOWN
Conditions: Epilepsy
Interventions: DRUG: Omega-3
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT