pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Abatacept in the Treatment and Prevention of Active Systemic Lupus Erythematosus (SLE) Flares in Combination With Prednisone
Status: COMPLETED
Conditions: Systemic Lupus Erythematosus
Interventions: DRUG: Abatacept|DRUG: Placebo|DRUG: Prednisone|DRUG: Abatacept
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Comparison of Conventional Physical Therapy, Powered Exoskeleton, and Hybrid Physical Therapy With Exoskeleton
Status: RECRUITING
Conditions: Stroke
Interventions: OTHER: Hybrid combination of physical therapy and powered exoskeleton|OTHER: Powered Exoskeleton Only|OTHER: Physical Therapy only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Dexmedetomidine on Intravenous Anesthetic Requirements for Children Undergoing Dental Procedures
Status: COMPLETED
Conditions: Anesthetic Sparing
Interventions: DRUG: Dexmedetomidine|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy, Safety and Tolerability of the Co-administration of NVA237 Plus Indacaterol Once Daily Versus Indacaterol Once Daily in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: DRUG: NVA237 50 µg and indacaterol 150 µg|DRUG: Placebo to NVA237 and indacaterol 150 µg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ischaemia-réperfusion During the Coronary Surgery With Beating Heart
Status: UNKNOWN
Conditions: Ischaemia-reperfusion Injury
Interventions: DRUG: Placebo|DRUG: Diltiazem|DRUG: Acetylcystein|DRUG: diltiazem and acetylcystein
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparative Study of Artekin With Standard Malarial Treatment Regimes in Afghanistan
Status: COMPLETED
Conditions: Uncomplicated Falciparum Malaria|Vivax Malaria
Interventions: DRUG: Dihydroartemisinin + Piperaquine (Artekin)|DRUG: artesunate-sulphadoxin/pyrimethamine, chloroquine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Proof-of-concept Clinical Trial Assessing the Safety of the Coordinated Undermining of Survival Paths by 9 Repurposed Drugs Combined With Metronomic Temozolomide (CUSP9v3 Treatment Protocol) for Recurrent Glioblastoma
Status: COMPLETED
Conditions: Glioblastoma
Interventions: DRUG: Temozolomide|DRUG: Aprepitant|DRUG: Minocycline|DRUG: Disulfiram|DRUG: Celecoxib|DRUG: Sertraline|DRUG: Captopril|DRUG: Itraconazole|DRUG: Ritonavir|DRUG: Auranofin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Cholecystectomy in Patients With Mild Gallstone Acute Pancreatitis
Status: TERMINATED
Conditions: Gallstone Pancreatitis
Interventions: PROCEDURE: Early cholecystectomy|PROCEDURE: Control (Delayed cholecystectomy)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low cArbohydraTe dIeT and aUtomated Insulin Delivery System for Type 1 DiabetEs
Status: NOT_YET_RECRUITING
Conditions: Type 1 Diabetes
Interventions: BEHAVIORAL: Low-carb diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Retrograde Intraarticular Injection Via Drain Tube, Topical Soaking of Tranexamic Acid (TXA), or Placebo in Elderly Patients With Femoral Neck Fractures Undergoing Cementless Bipolar Hemiarthroplasty - a Randomized Controlled Trial
Status: NOT_YET_RECRUITING
Conditions: Femoral Neck Fracture|Bipolar Hemiarthroplasty
Interventions: DRUG: Topical tranexamic acid administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prophylaxis Regimen for Hemophilia A Patients
Status: RECRUITING
Conditions: Hemophilia A|Prophylaxis of Bleeding
Interventions: BIOLOGICAL: Damoctocog alfa-pegol is a recombinant B-domain deleted human coagulation FVIII variant site specifically conjugated with a 60 kDa, branched (30 kDa each) polyethylene glycol (PEG).
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Creon 40,000 for Treatment of PEI (Pancreatic Exocrine Insufficiency) Due to Chronic Pancreatitis
Status: COMPLETED
Conditions: Pancreatic Insufficiency
Interventions: DRUG: Pancreatin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Different Doses of Dexmedetomidine in External Oblique Intercostal Plane Block in Splenectomy
Status: RECRUITING
Conditions: Dexmedetomidine|External Oblique Intercostal Plane Block|Splenectomy
Interventions: DRUG: Dexmedetomidine 0.5 μg/kg|DRUG: Dexmedetomidine 1 μg/kg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: AZD0530 (NSC 735464) in Treating Patients With Previously Treated Metastatic Colon Cancer or Rectal Cancer
Status: TERMINATED
Conditions: Adenocarcinoma of the Colon|Adenocarcinoma of the Rectum|Recurrent Colon Cancer|Recurrent Rectal Cancer|Stage IV Colon Cancer|Stage IV Rectal Cancer
Interventions: DRUG: saracatinib|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acute Effect of Lorazepam on Brain Activity Measured by Magnetoencephalograpy (MEG) and Electroencephalography (EEG)
Status: UNKNOWN
Conditions: Healthy Subjects
Interventions: DRUG: Lorazepam|DRUG: Lorazepam|DRUG: Lorazepam|DRUG: Lorazepam|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparison of Nebulizers in ED in Pediatric Asthma Patients
Status: TERMINATED
Conditions: Asthma
Interventions: DEVICE: Hudson RCI® nebulizer|DEVICE: NebuTech® HDN® nebulizer|DRUG: Albuterol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Tech and Telephone Smoking Cessation Treatment for Young Veterans With PTSD
Status: COMPLETED
Conditions: Smoking Cessation
Interventions: BEHAVIORAL: Tech-Facilitated IC Intervention|BEHAVIORAL: VA Quitline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessing Timing of Enteral Feeding Support in Esophageal Cancer Patients on Muscle functTion and Survival
Status: RECRUITING
Conditions: Esophageal Cancer|Nutrition Aspect of Cancer|Postoperative Complications|Muscle Weakness|Sarcopenia|Jejunostomy; Complications
Interventions: OTHER: delayed start enteral support @ POD5
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Switching From Ticagrelor to Prasugrel in Patients With Acute Coronary Syndrome
Status: RECRUITING
Conditions: Acute Coronary Syndrome
Interventions: DRUG: Prasugrel 10 mg p.o|DRUG: Ticagrelor 90 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Pharmacokinetics, Feasibility, Acceptability, and Safety of Oral Pre-Exposure Prophylaxis for HIV Prevention During Pregnancy and Postpartum
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Emtricitabine/Tenofovir Disoproxil Fumarate (FTC/TDF)|BEHAVIORAL: Behavioral HIV risk reduction package
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Trial to Study the Effects of Supplementary Omega-3 on Serum C-Reactive Protein Levels
Status: TERMINATED
Conditions: Coronary Artery Disease|Inflammatory Response|Atherosclerosis
Interventions: DIETARY_SUPPLEMENT: eicosapentaenoic acid (EPA),
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dasatinib and Ipilimumab in Treating Patients With Gastrointestinal Stromal Tumors or Other Sarcomas That Cannot Be Removed by Surgery or Are Metastatic
Status: COMPLETED
Conditions: Gastrointestinal Stromal Tumor|Stage III Soft Tissue Sarcoma|Stage IV Soft Tissue Sarcoma
Interventions: DRUG: Dasatinib|BIOLOGICAL: Ipilimumab|OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacological Study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunological Response of Bladder Cancer Patients Under BCG
Status: SUSPENDED
Conditions: Bladder Cancer|Bacillus Calmette-Guerin
Interventions: BIOLOGICAL: Bacillus Calmette Guerin|OTHER: PLACEBO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: HAIC+Lenvatinib+Tislelizumab vs D-TACE+Lenvatinib+Tislelizumab for Unresectable HCC
Status: RECRUITING
Conditions: Unresectable Hepatocellular Carcinoma
Interventions: DRUG: D-TACE|DRUG: HAIC|DRUG: Lenvatinib|DRUG: tislelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Standard Chemotherapy Plus Moxifloxacin as First-line Treatment for Metastatic Triple-negative Breast Cancer
Status: RECRUITING
Conditions: Triple Negative Breast Cancer
Interventions: DRUG: Gemcitabine and carboplatin plus antibiotic (moxifloxacin)|DRUG: Gemcitabine combined with carboplatin plus placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Durvalumab and SNDX-6532 Following Chemo or Radio-Embolization for Patients With Intrahepatic Cholangiocarcinoma
Status: COMPLETED
Conditions: Unresectable Intrahepatic Cholangiocarcinoma
Interventions: DRUG: Durvalumab|DRUG: SNDX-6352
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of E7777 in Patients With Relapsed or Refractory Peripheral T-cell Lymphoma and Cutaneous T-cell Lymphoma
Status: COMPLETED
Conditions: Peripheral T-cell Lymphoma|Cutaneous T-cell Lymphoma
Interventions: DRUG: E7777
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Extension Follow-up Trial to Evaluate the Long-term Safety of Children and Adolescent Participants With Euvolemic or Hypervolemic Hyponatremia
Status: TERMINATED
Conditions: Hyponatremia
Interventions: DRUG: Tolvaptan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Platelet Function and Safety After IV and Oral Diclofenac, IV Ketorolac and Oral Aspirin in Adult Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: intravenous diclofenac sodium (DIC075V)|DRUG: ketorolac|DRUG: oral diclofenac (Cataflam)|DRUG: aspirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PD Study to Assess Phosphate Binding Characteristics of K2CG Chewing Gum
Status: COMPLETED
Conditions: Hyperphosphatemia|Chronic Kidney Disease
Interventions: OTHER: K2CG chewing gum|OTHER: K2CG chewing gum|OTHER: K2CG chewing gum|OTHER: K2CG chewing gum
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: Famitinib in Combination With Camrelizumab and TPC in The First-line Treatment of Immunomodulatory Locally Advanced or Metastatic TNBC.
Status: RECRUITING
Conditions: Triple-Negative Breast Cancer
Interventions: DRUG: Famitinib|DRUG: Camrelizumab|DRUG: nab-Palitaxel/Capecitabine/Eribulin Mesylate/Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acalabrutinib and Anti-CD19 CAR T-cell Therapy for the Treatment of B-cell Lymphoma
Status: RECRUITING
Conditions: B-Cell Non-Hodgkin Lymphoma|Diffuse Large B-Cell Lymphoma, Not Otherwise Specified|High Grade B-Cell Lymphoma|Primary Mediastinal (Thymic) Large B-Cell Lymphoma|Transformed Follicular Lymphoma to Diffuse Large B-Cell Lymphoma|Grade 1 Follicular Lymphoma|Grade 2 Follicular Lymphoma|Grade 3a Follicular Lymphoma
Interventions: DRUG: Acalabrutinib|BIOLOGICAL: Axicabtagene Ciloleucel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PETHEMA-LMA10: Treatment of Acute Myeloblastic Leukemia (AML) in Patients Less Than or Equal to 65 Years
Status: UNKNOWN
Conditions: Acute Myeloblastic Leukemia
Interventions: DRUG: IDARUBICINE|DRUG: ARA-C
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose-Escalation Study Of SB-485232 Administered As Daily Subcutaneous Injections In Adults With Solid Tumors
Status: COMPLETED
Conditions: Solid Tumor Cancer
Interventions: DRUG: SB-485232
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Epidural Oxycodone and Epidural Morphine
Status: COMPLETED
Conditions: Pruritus
Interventions: DRUG: Opioid administration oxycodone|DRUG: Opioid administration morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Efficacy and Safety of Two Doses of GSK2857916 in Participants With Multiple Myeloma Who Have Failed Prior Treatment With an Anti-CD38 Antibody
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: Belantamab mafodotin frozen liquid|DRUG: Belantamab mafodotin lyophilized powder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sub Omohyoid Suprascapular Nerve Block Versus Interscalene Nerve Block
Status: RECRUITING
Conditions: Post Operative Pain|Regional Anesthesia|Nerve Block
Interventions: PROCEDURE: subomohyoid plane block|PROCEDURE: Interscalene brachial plexus block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Study of APN201 (Liposomal Recombinant Human Cu/Zn-Superoxide Dismutase) for the Prevention of Radiation-induced Dermatitis in Women With Breast Cancer
Status: COMPLETED
Conditions: Radiation Induced Dermatitis
Interventions: DRUG: APN201|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Phase Ib Study of Axatilimab in Combination with Olaparib in BRCA1/2 and PALB2- Associated Metastatic HER2-negative Breast Cancer
Status: RECRUITING
Conditions: Breast Cancer|PALB2-Mutated Breast Carcinoma|HER2-negative Breast Cancer|BRCA1 Mutation|BRCA2 Mutation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Conventional Versus Hypofractionated Radiotherapy With Temozolomide in Elderly Glioblastoma
Status: NOT_YET_RECRUITING
Conditions: Glioblastoma
Interventions: RADIATION: Hypofractionated radiotherapy|RADIATION: Conventional radiotherapy|DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Crossover Study to Assess the Bioequivalence of Hydrocodone Bitartrate Extended-Release Tablet
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: a 60 mg dose of the hydrocodone bitartrate extended-release tablet administered as either two 30-mg tablets (Treatment A) or one 60-mg tablet (Treatment B).
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of AVE1642 (IGF-1R/CD221) in Combination With Fulvestrant (Faslodex®) in Postmenopausal Patients With Advanced Hormono-dependent Breast Cancer
Status: TERMINATED
Conditions: Breast Neoplasms
Interventions: DRUG: AVE1642|DRUG: Fulvestrant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reshaping the Path of Mild Cognitive Impairment by Refining Exercise Prescription
Status: ACTIVE_NOT_RECRUITING
Conditions: Mild Cognitive Impairment
Interventions: BEHAVIORAL: Aerobic Training|BEHAVIORAL: Resistance Training|BEHAVIORAL: Balance and Tone Training|BEHAVIORAL: Balance and Tone Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Study of Imprime PGG and Pembrolizumab in Patients With HR+/HER2- Metastatic Breast Cancer (mBCA)
Status: COMPLETED
Conditions: Malignant Neoplasm of Breast
Interventions: BIOLOGICAL: Imprime PGG|BIOLOGICAL: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Clinical Trial of CNCT19 Cell Injection in the Treatment of Relapsed or Refractory Non-Hodgkin's Lymphoma
Status: RECRUITING
Conditions: Non-Hodgkin's Lymphoma
Interventions: BIOLOGICAL: single dose of CNCT19
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transarterial Chemoembolization (TACE) With or Without Stereotactic Body Radiotherapy (SBRT) in Hepatocellular Carinoma
Status: WITHDRAWN
Conditions: Hepatocellular Carcinoma
Interventions: PROCEDURE: transarterial chemoembolization|RADIATION: TACE plus RT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intratumoral Injection of IP-001 Following Thermal Ablation in Patients With Advanced Solid Tumors.
Status: RECRUITING
Conditions: Advanced Solid Tumors
Interventions: DRUG: IP-001|DEVICE: Thermal Ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radiation Therapy and Capecitabine/Oxaliplatin Chemotherapy in the Treatment of Locally Advanced Pancreas Adenocarcinoma
Status: COMPLETED
Conditions: Cancer|Pancreas
Interventions: RADIATION: Radiation Therapy|DRUG: Capecitabine|DRUG: Oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of a Self-Directed Exercise Program (SDEP) Following Selected Lower Extremity Fractures
Status: COMPLETED
Conditions: Musculoskeletal Injury
Interventions: BEHAVIORAL: Self-Directed Exercise Program|BEHAVIORAL: Clinic-Based Physical
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Olaparib and Ramucirumab in Treating Patients With Metastatic or Locally Recurrent Gastric or Gastroesophageal Junction Cancer That Cannot Be Removed by Surgery
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Esophageal Carcinoma|Metastatic Gastric Carcinoma|Metastatic Gastroesophageal Junction Adenocarcinoma|Recurrent Esophageal Carcinoma|Recurrent Gastric Carcinoma|Recurrent Gastroesophageal Junction Adenocarcinoma|Stage III Esophageal Cancer AJCC v7|Stage III Gastric Cancer AJCC v7|Stage IV Esophageal Cancer AJCC v7|Stage IV Gastric Cancer AJCC v7|Unresectable Esophageal Carcinoma|Unresectable Gastric Carcinoma|Unresectable Gastroesophageal Junction Adenocarcinoma
Interventions: DRUG: Olaparib|BIOLOGICAL: Ramucirumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Effect of Total Intravenous Anesthesia and Inhalation Anesthesia on Cancer Cell Cytotoxicity, Micrometastasis and Recurrence of Tumor in Patients Undergoing Breast Tumor Resection
Status: TERMINATED
Conditions: Breast Cancer
Interventions: PROCEDURE: intravenous anesthesia|PROCEDURE: inhalation anesthesia|DRUG: propofol-remifentanil|DRUG: sevoflurane-remifentanil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Efficacy of EMF BCI Based Device on Acute Stroke
Status: TERMINATED
Conditions: Acute Stroke
Interventions: DEVICE: BQ|DEVICE: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Safety of Aracmyn in Patients With Systemic Latrodectism
Status: COMPLETED
Conditions: Arachnidism|Latrodectism
Interventions: BIOLOGICAL: widow spider antivenom|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sharp Dissection Versus Monopolar Electrocautery in Primary Total Knee Arthroplasty Performed Under Tourniquet
Status: UNKNOWN
Conditions: Osteo Arthritis Knee|Arthroplasty, Replacement, Knee
Interventions: PROCEDURE: Sharp dissection with scalpel plus electrocautery to vessels|PROCEDURE: Electrocautery for all dissection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Three Anti-HIV Drug Combinations Containing Saquinavir Soft Gelatin Capsules Used in HIV-1 Infected Patients
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Ritonavir|DRUG: Nelfinavir mesylate|DRUG: Saquinavir|DRUG: Delavirdine mesylate|DRUG: Lamivudine|DRUG: Stavudine|DRUG: Zidovudine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: HOMEStudy: Development of a Home-based Self-delivered Prehabilitation Intervention to Proactively Reduce Fall Risk in Older Adults
Status: COMPLETED
Conditions: Mobility Limitation|Aging
Interventions: DEVICE: Home-based mobility testing and active tDCS|DEVICE: Sham tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Signature Acetabular Posterior/Lateral Data Collection
Status: TERMINATED
Conditions: Noninflammatory Degenerative Joint Disease|Avascular Necrosis|Rheumatoid Arthritis
Interventions: DEVICE: Posterior Lateral Approach Total Hip Arthroplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Safety, Tolerability, Pharmacokinetic, and Efficacy of ABY-035/AFO2
Status: COMPLETED
Conditions: Psoriasis
Interventions: BIOLOGICAL: ABY-035/AFO2
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pharmacokinetic Study of a Single-Dose of Diazepam Nasal Spray in Adult Epileptic Patients Experiencing a Seizure Episode
Status: COMPLETED
Conditions: Epilepsy
Interventions: DRUG: Diazepam
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ROVUS Asia Registry (Evaluate Safety and Effectiveness of Rotational Atherectomy and Intravascular Ultrasound for Heavily Calcified Coronary Lesion)
Status: RECRUITING
Conditions: Coronary Artery Calcification
Interventions: PROCEDURE: Rotational Atherectomy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety of F-18 FPCIT PET in Parkinson's Disease and Essential Tremor Patients
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: PROCEDURE: PET/CT|DRUG: F-18 FPCIT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Telephone Acceptance and Commitment Therapy Intervention for Caregivers of Adults With ADRD
Status: COMPLETED
Conditions: Anxiety|Caregiver Burden
Interventions: BEHAVIORAL: Telephone Acceptance and Commitment Therapy Intervention for Caregivers of Adults with Alzheimer's Disease and Related Dementias
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Bio-Integrative, Fiber-Reinforced Kneebar for Treating Subchondral Insufficiency of the Knee
Status: NOT_YET_RECRUITING
Conditions: Subchondral Insufficiency Fracture
Interventions: DEVICE: OSSIOfiber® Trimmable Fixation Nails
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Distal Locking Using an Electromagnetic Field Guided Computer Based Real Time System for Orthopaedic Trauma Patients
Status: COMPLETED
Conditions: Tibial Fractures|Femoral Fractures
Interventions: PROCEDURE: free-hand|PROCEDURE: Wand technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mobile Health Interventions for Medication Adherence Among PLWH
Status: WITHDRAWN
Conditions: HIV/AIDS|Smoking|Smoking Cessation|HIV
Interventions: DRUG: Varenicline|DEVICE: Mobile phone application|BEHAVIORAL: Contingency management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Application of Transcutaneous Trigeminal Nerve Stimulation and Sound Fusion Stimulation on Tinnitus
Status: COMPLETED
Conditions: Tinnitus
Interventions: DEVICE: A transcutaneous trigeminal nerve stimulator: High Frequency|DEVICE: A transcutaneous trigeminal nerve stimulator: Low Frequency|DEVICE: A transcutaneous trigeminal nerve stimulator: Sham|DEVICE: Sound Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess Safety of Canagliflozin and Metformin Hydrochloride Combination Given as a Supplement to Diet and Exercise to Improve Blood Sugar Level in Indian Adult Participants With Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: DRUG: Canagliflozin + Metformin hydrochloride (Fixed Dose Combination)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Combination of IVIG, Dexamethasone and a Megadose of PBSCs for Decreasing DSAs
Status: COMPLETED
Conditions: Blood Disease
Interventions: COMBINATION_PRODUCT: intravenous immunoglobulin, dexamethasone and a megadose of peripheral-blood stem cell transfusion
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pilot Study Evaluating Broccoli Sprouts in Advanced Pancreatic Cancer [POUDER Trial]
Status: UNKNOWN
Conditions: Pancreatic Ductal Adenocarcinoma
Interventions: DIETARY_SUPPLEMENT: Verum, broccoli sprout grain|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MYOHEART™ (Myogenesis Heart Efficiency and Regeneration Trial)
Status: UNKNOWN
Conditions: Congestive Heart Failure|Coronary Artery Disease|Myocardial Infarction
Interventions: DRUG: MyoCell™|DEVICE: MyoCath™
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: FOot CAre and Exercises ImplementatioN for People With Diabetes in Primary Care
Status: ENROLLING_BY_INVITATION
Conditions: Diabetes; Neuropathy, Polyneuropathy (Manifestation)
Interventions: OTHER: Foot-related exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tolerance and Digestibility of a New Formula in Healthy Infants
Status: COMPLETED
Conditions: Steatorrhea|Growth
Interventions: DIETARY_SUPPLEMENT: dairy lipids and soluble milk proteins
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy and Safety of the Biosimilar Ranibizumab FYB201 in Comparison to Lucentis in Patients With Neovascular Age-related Macular Degeneration
Status: COMPLETED
Conditions: Age-related Macular Degeneration (AMD)
Interventions: BIOLOGICAL: ranibizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Effects of Myofascial Arm Pull Technique and Post Isometric Relaxation on Pain, Range of Motion and Functional Disability in Adhesive Capsulitis After Mastectomy
Status: RECRUITING
Conditions: Adhesive Capsulitis
Interventions: OTHER: Post Isometric Relaxation|OTHER: Myofascial arm pull technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hepatobiliary Manifestations Following Two-Stages Elective Laparoscopic Restorative Proctocolectomy for Patients With Ulcerative Colitis. A Prospective Observational Study.
Status: COMPLETED
Conditions: Hepatobiliary Disease
Interventions: PROCEDURE: laparoscopic restorative proctocolectomy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Stepped Care for Children After Trauma: Optimizing Treatment
Status: COMPLETED
Conditions: Posttraumatic Stress Disorder
Interventions: BEHAVIORAL: Stepped Care TF-CBT|BEHAVIORAL: Standard TF-CBT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Probiotics in GastroIntestinal Disorders
Status: UNKNOWN
Conditions: Ulcerative Colitis|Crohn's Disease
Interventions: BIOLOGICAL: Bifidobacterium infantis 35624|BIOLOGICAL: Lactobacillus salivarius UCC118|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Vision and Balance Changes After Bilateral Implantation of Toric IOLs
Status: RECRUITING
Conditions: Cataract Bilateral|Astigmatism Bilateral
Interventions: DEVICE: Toric intraocular lens Zeiss AT TORBI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors
Status: RECRUITING
Conditions: Advanced Solid Tumor|Melanoma|Head and Neck Cancer|Gastric Cancer|Ovarian Carcinoma|Cervical Cancer|Endometrial Cancer|Bladder Cancer|Esophageal Cancer|Pancreatic Carcinoma|Prostate Cancer
Interventions: DRUG: HER3-DXd
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Implementation of a HABIT-ILE Intervention at William Lennox Neurological Hospital (NeuREHA)
Status: RECRUITING
Conditions: Acquired Brain Injury
Interventions: BEHAVIORAL: HABIT-ILE|BEHAVIORAL: Conventional intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Differences Between Chidamide Taken Daily and Twice a Week in Therapeutic Effect，Pharmacokinetics, Pharmacodynamics and EB Virus Activation
Status: UNKNOWN
Conditions: Lymphoma, Extranodal NK-T-Cell|EBV
Interventions: DRUG: Chidamide BIW|DRUG: Chidamide QD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: FEcal Transplant, a Hope to Eradicate Colonization of Patient Harboring eXtreme Drug Resistant Bacteria?
Status: COMPLETED
Conditions: Microbial Colonization|Bacterial Peritonitis|Faeces Smearing
Interventions: DRUG: fecal microbiota transplant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of a Probiotic in Hypertension
Status: ACTIVE_NOT_RECRUITING
Conditions: Hypertension
Interventions: DIETARY_SUPPLEMENT: Vivomixx®|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Rucaparib in Patients With Pancreatic Cancer and a Known Deleterious BRCA Mutation
Status: COMPLETED
Conditions: Pancreatic Cancer|Pancreatic Ductal Adenocarcinoma
Interventions: DRUG: Rucaparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Autologous Blood, Corticosteroid, and Their Combined Injection for Treating Lateral Epicondylitis
Status: COMPLETED
Conditions: Lateral Epicondylitis|Comparing Autologous Blood Corticosteroid and Their Combined Injection for Treating Lateral Epicondylitis
Interventions: DRUG: Corticosteroid|DRUG: Autologous Blood|DRUG: Local Anesthetic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Contrasting Ketogenic and Mediterranean Diets in Individuals With Type 2 Diabetes and Prediabetes: The Keto-Med Trial
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|PreDiabetes
Interventions: BEHAVIORAL: Mediterranean Diet (Med-Plus)|BEHAVIORAL: Well-Formulated Ketogenic Diet (WFKD)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Phase 3 Evaluation of Daclatasvir and Asunaprevir in Treatment-naive Subjects With Chronic Hepatitis C Genotype 1b Infection
Status: COMPLETED
Conditions: Hepatitis C
Interventions: DRUG: Daclatasvir|DRUG: Asunaprevir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of IBI351 in Combination With Sintilimab ± Chemotherapy in Advanced Non-squamous Non-small Cell Lung Cancer Subjects With KRAS G12C Mutation
Status: RECRUITING
Conditions: Advanced Non-Small Cell Lung Cancer
Interventions: DRUG: pemetrexed|DRUG: cis-platinum|DRUG: Sintilimab|DRUG: IBI351|DRUG: carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Breast Cancer Treatment on Joint Health, Cartilage Composition, and Bone Structure in the Knee and Hand
Status: TERMINATED
Conditions: Anatomic Stage I Breast Cancer AJCC v8|Anatomic Stage IA Breast Cancer AJCC v8|Anatomic Stage IB Breast Cancer AJCC v8|Anatomic Stage II Breast Cancer AJCC v8|Anatomic Stage IIA Breast Cancer AJCC v8|Anatomic Stage IIB Breast Cancer AJCC v8|Anatomic Stage III Breast Cancer AJCC v8|Anatomic Stage IIIA Breast Cancer AJCC v8|Anatomic Stage IIIB Breast Cancer AJCC v8|Anatomic Stage IIIC Breast Cancer AJCC v8|Hormone Receptor Positive Breast Adenocarcinoma|Prognostic Stage I Breast Cancer AJCC v8|Prognostic Stage IA Breast Cancer AJCC v8|Prognostic Stage IB Breast Cancer AJCC v8|Prognostic Stage II Breast Cancer AJCC v8|Prognostic Stage IIA Breast Cancer AJCC v8|Prognostic Stage IIB Breast Cancer AJCC v8|Prognostic Stage III Breast Cancer AJCC v8|Prognostic Stage IIIA Breast Cancer AJCC v8|Prognostic Stage IIIB Breast Cancer AJCC v8|Prognostic Stage IIIC Breast Cancer AJCC v8
Interventions: PROCEDURE: Magnetic Resonance Imaging|OTHER: Questionnaire Administration
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety of Canadá Association in the Treatment of Chronic Pain
Status: WITHDRAWN
Conditions: Pain, Chronic
Interventions: DRUG: Canadá|OTHER: Canadá placebo|DRUG: Dipyrone|OTHER: Dipyrone placebo|DRUG: Tramadol hydrochloride|OTHER: Tramadol hydrochloride placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: BURULICO Drug Trial Study Protocol: RCT SR8/SR4+CR4, GHANA
Status: COMPLETED
Conditions: Buruli Ulcer|Mycobacterium Ulcerans
Interventions: DRUG: SR4 - switch to CR4
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety and Efficacy of Minocycline Ointment in Subjects With Inflamed Meibomian Gland Dysfunction
Status: COMPLETED
Conditions: Meibomian Gland Dysfunction|MGD-Meibomian Gland Dysfunction
Interventions: DRUG: 0.3% Topical Minocycline Ointment|DRUG: 1% Topical Minocycline Ointment|OTHER: Topical Vehicle Ointment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Role of Liquid Phase Concentrated Growth Factors vs. Hypertonic Dextrose Prolotherapy for Management of Patients With Disc Displacement Without Reduction
Status: COMPLETED
Conditions: Temporomandibular Joint Disorders|Temporomandibular Disorder
Interventions: DRUG: Hypertonic Dextrose Solution|BIOLOGICAL: Liquid Phase Concentrated Growth Factor (LPCGFs)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective Real-World Study of HAIC With Raltitrexed or 5-Fluorouracil for the Treatment of Hepatocellular Carcinoma
Status: RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: hepatic artery infusion chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: randOmized stUdy Using acceleromeTry to Compare Sacubitril/valsarTan and Enalapril in Patients With Heart Failure
Status: COMPLETED
Conditions: Chronic Heart Failure With Reduced Ejection Fraction
Interventions: DRUG: LCZ696 (Sacubitril/Valsartan)|DRUG: Placebo of LCZ696 (Sacubitril/Valsartan)|DRUG: Enalapril|DRUG: Placebo of Enalapril
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: tDCS and Metacognitive Strategy Training in Stroke
Status: RECRUITING
Conditions: Chronic Stroke
Interventions: BEHAVIORAL: CO-OP Procedures|DEVICE: tDCS|BEHAVIORAL: Computer Cognitive Training Procedures|DEVICE: sham tDCS group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Maintenance Dosing of Vitamin D in Crohn's Disease
Status: TERMINATED
Conditions: Crohns Disease|Vitamin D Deficiency
Interventions: DIETARY_SUPPLEMENT: 5000 IU D3|DIETARY_SUPPLEMENT: 1000 IU D3|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Perceptions,Social Representations and Experience of Lyme Borreliosis and Ticks in Adolescents Likely to be Infected and Their Parents
Status: COMPLETED
Conditions: Lyme Disease
Interventions: OTHER: semi-directed interview concerning the experience of adolescents and their parents on Lyme borreliosis and on the tick.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparing Fluoride Varnish and Sealant to Prevent White Spots in Orthodontic Patients
Status: COMPLETED
Conditions: White Spot Lesion
Interventions: DEVICE: Pro Seal Sealant|DEVICE: MI Varnish
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: DEtection of Cellular Inflammation With FERumoxytol in the HEART
Status: COMPLETED
Conditions: Cardiac Transplant|Cardiac Sarcoid|Myocarditis|Healthy Volunteers
Interventions: DRUG: Ferumoxytol
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Association of Preoperative Sarcopenia and Intraoperative Hypotension in Patients Undergoing Minimally Invasive Pylorus Preserving Pancreaticoduodenectomy : Prospective Observational Study
Status: UNKNOWN
Conditions: Patients Undergoing Minimally Invasive Pylorus Preserving Pancreaticoduodenectomy
Interventions: DEVICE: Hand grip test, computed tomography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Cardboard Cot in Neonatal Thermoregulation: A Randomized Cross Over Trial
Status: WITHDRAWN
Conditions: Infant, Premature|Hypothermia, Newborn
Interventions: OTHER: Cardboard Cot Care|OTHER: Incubator Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Metformin for the Minimization of Geographic Atrophy Progression in Patients With AMD
Status: COMPLETED
Conditions: Age-Related Macular Degeneration|Macular Degeneration, Age-Related|Dry Macular Degeneration|Geographic Atrophy
Interventions: DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lenalidomide After Donor Bone Marrow Transplant in Treating Patients With High-Risk Hematologic Cancers
Status: COMPLETED
Conditions: Adult Acute Myeloid Leukemia in Remission|Adult Acute Myeloid Leukemia With Inv(16)(p13.1q22); CBFB-MYH11|Adult Acute Myeloid Leukemia With t(16;16)(p13.1;q22); CBFB-MYH11|Adult Acute Myeloid Leukemia With t(8;21); (q22; q22.1); RUNX1-RUNX1T1|Adult Acute Myeloid Leukemia With t(9;11)(p22.3;q23.3); MLLT3-KMT2A|Adult Acute Promyelocytic Leukemia With PML-RARA|Adult Grade III Lymphomatoid Granulomatosis|Adult Nasal Type Extranodal NK/T-Cell Lymphoma|Alkylating Agent-Related Acute Myeloid Leukemia|Anaplastic Large Cell Lymphoma|Angioimmunoblastic T-Cell Lymphoma|Extranodal Marginal Zone Lymphoma of Mucosa-Associated Lymphoid Tissue|Hepatosplenic T-Cell Lymphoma|Intraocular Lymphoma|Lymphomatous Involvement of Non-Cutaneous Extranodal Site|Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma|Nodal Marginal Zone Lymphoma|Post-Transplant Lymphoproliferative Disorder|Primary Cutaneous B-Cell Non-Hodgkin Lymphoma|Prolymphocytic Leukemia|Recurrent Adult Burkitt Lymphoma|Recurrent Adult Grade III Lymphomatoid Granulomatosis|Recurrent Adult Immunoblastic Lymphoma|Recurrent Adult Lymphoblastic Lymphoma|Recurrent Adult T-Cell Leukemia/Lymphoma|Recurrent Grade 1 Follicular Lymphoma|Recurrent Grade 2 Follicular Lymphoma|Recurrent Grade 3 Follicular Lymphoma|Recurrent Mantle Cell Lymphoma|Recurrent Marginal Zone Lymphoma|Recurrent Mycosis Fungoides and Sezary Syndrome|Recurrent Non-Hodgkin Lymphoma|Recurrent Primary Cutaneous T-Cell Non-Hodgkin Lymphoma|Recurrent Small Lymphocytic Lymphoma|Refractory Chronic Lymphocytic Leukemia|Refractory Hairy Cell Leukemia|Richter Syndrome|Small Intestinal Lymphoma|Splenic Marginal Zone Lymphoma|T-Cell Large Granular Lymphocyte Leukemia|Testicular Lymphoma|Waldenstrom Macroglobulinemia
Interventions: OTHER: Laboratory Biomarker Analysis|DRUG: Lenalidomide|OTHER: Pharmacological Study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Role of Simvastatin Microsponges in Treatment of Periodontitis
Status: COMPLETED
Conditions: Periodontitis
Interventions: PROCEDURE: open flap subgingival debridement|PROCEDURE: Subgingival injection of chitosan 2% gel|PROCEDURE: Subgingival injection of chitosan 2% gel|PROCEDURE: Subgingival injection of chitosan 2% gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Fentanyl Sublingual Spray for the Treatment of Moderate to Severe Post-Operative Pain
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Fentanyl|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Subcostal Transverse Abdominis Plane Block for Epigastric Cardiac Pacemaker Operation
Status: COMPLETED
Conditions: Congenital Heart Disease
Interventions: PROCEDURE: SC TAP|PROCEDURE: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Salivary pH After Consuming Milk of Origin Vegetable vs Cow's Milk in Children
Status: COMPLETED
Conditions: pH
Interventions: DIETARY_SUPPLEMENT: Comparison of salivary pH after consuming milk of origin vegetable vs cow's milk
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER