pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Study of the Placental Methylome of Dichorionic and Monochorionic Monozygotic Twin Pairs to Establish a Timeline of Epigenetic Programming
Status: ACTIVE_NOT_RECRUITING
Conditions: Twin Placenta
Interventions: OTHER: saliva sample|OTHER: questionnaire
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Bacterial Microbiota Characterization on Implant-supported PEEK and Titanium Provisional Abutments
Status: COMPLETED
Conditions: Peri-implant Mucositis|Oral Bacterial Infection|Bacterial Resistance
Interventions: DEVICE: Provisional abutment material
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: PERgoveriS In Stratified Treatment for Assisted Reproductive Technique
Status: COMPLETED
Conditions: Assisted Reproductive Techniques|Reproductive Technology, Assisted
Interventions: DRUG: Gonal-f®|DRUG: Pergoveris®|DRUG: Pergoveris®|DRUG: Recombinant human chorionic gonadotropin (r-hCG)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mindfulness Based Stress Reduction for Intellectually Able Autistic Adults
Status: TERMINATED
Conditions: Treatment Satisfaction|Participation Rate, Patient|Quality of Life|Mental Illness|Acceptance Processes|Stress, Psychological
Interventions: BEHAVIORAL: Mindfulness-based stress reduction (MBSR)|BEHAVIORAL: Treatment as usual (TAU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Single Ascending and Multiple Dose Study to Evaluate Safety, Tolerability, and PK of MYMD1 in Healthy Male and Female Adult Subjects
Status: COMPLETED
Conditions: Hashimoto Disease
Interventions: DRUG: MYMD-1|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial to Assess Brexpiprazole Versus Placebo for the Treatment of Acute Manic Episodes, Associated With Bipolar I Disorder
Status: COMPLETED
Conditions: Bipolar I Disorder|Manic Episode
Interventions: DRUG: Brexpiprazole|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Families Expectations and Hope Raised by an Evaluation of Consciousness in Patients in a Vegetative State
Status: COMPLETED
Conditions: Disorders of Consciousness|Qualitative Research|Ethics|Neuroimaging
Interventions: OTHER: Semi structured interviews + EEG exams
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Daily Consumption of Well-Cooked Broccoli May Affect Glucosinolate Metabolites and Inflammatory Biomarkers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: OTHER: Control Diet|OTHER: Base Diet with Broccoli
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Traditional Martial Arts, Open and Locked Exercise on the Physical and Mental Health of Drug Users
Status: COMPLETED
Conditions: Drug Use
Interventions: BEHAVIORAL: Health Qigong - 12-Step Daoyin Health Preservation Exercises|BEHAVIORAL: Locked exercise|BEHAVIORAL: Multiplayer open exercise|BEHAVIORAL: Health Qigong - 12-Step Daoyin Health Preservation Exercises combined with locked exercise|BEHAVIORAL: Health Qigong - 12-Step Daoyin Health Preservation Exercises combined with open exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Oral Aprepitant and Lower Dose Dexamethasone Versus Aprepitant Alone for Preventing Postoperative Nausea and Vomiting (PONV) After Elective Laparoscopic Surgeries
Status: UNKNOWN
Conditions: Nausea|Vomiting
Interventions: DRUG: Dexamethasone|DRUG: Aprepitant|DRUG: Placebo Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of the Psychoeducation Program on the Subjective Well-being of Caregivers
Status: UNKNOWN
Conditions: Schizophrenia|Caregiver|Psychoeducation|Communication Skills|Well-being
Interventions: OTHER: Communication skills psychoeducation|OTHER: General psychoeducation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Efficacy and Safety of Nasal Filters on Seasonal Allergic Rhinitis (Hay Fever)
Status: COMPLETED
Conditions: Rhinitis, Allergic, Seasonal
Interventions: DEVICE: Nasal filter|DEVICE: Placebo nasal filter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nutritional Therapy Interventions in Heart Failure
Status: COMPLETED
Conditions: Heart Failure NYHA Class II
Interventions: DIETARY_SUPPLEMENT: EAA mixture|DIETARY_SUPPLEMENT: Placebo (whey protein)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: High Dose vs. Standard Influenza Vaccine in Adult SOT
Status: COMPLETED
Conditions: Influenza|Immunosuppression
Interventions: BIOLOGICAL: Fluzone High-dose Influenza Vaccine|BIOLOGICAL: Standard 2016-2017 Flu vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Does Vessel-sparing Surgery in Anterior Approach Total Hip Arthroplasty Change Clinical Outcome?
Status: NOT_YET_RECRUITING
Conditions: Tensor Fasciae Latae Syndrome|Arthroplasty Complications
Interventions: PROCEDURE: Vessel technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dexmedetomidine PKPD Modeling and the Influence of Auditory Stimulation on Dexmedetomidine Effect
Status: COMPLETED
Conditions: Anesthesia|Sedation
Interventions: OTHER: Non-stimulation|OTHER: Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of Denufosol Inhalation Solution in Patients With Mild to Moderate Cystic Fibrosis Lung Disease
Status: TERMINATED
Conditions: Cystic Fibrosis
Interventions: DRUG: denufosol tetrasodium (INS37217) Inhalation Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of IntraVenous ImmunoGlobulins in Toxic Shock Syndromes: a Paediatric Pilot Study
Status: COMPLETED
Conditions: Toxic Shock Syndrome
Interventions: DRUG: Intravenous human immunoglobulin|DRUG: Albumin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Evaluating of Role of Myeloperoxidase in Prediction of Outcomes of Cardiac Surgery Procedures.
Status: RECRUITING
Conditions: Cardiac Procedure Complication|Ischemic Heart Disease|Valve Heart Disease|Defect Septal
Interventions: OTHER: On-pump CABG|OTHER: Off-pump CABG|OTHER: Pump-assisted CABG|OTHER: Valve Repair Procedure without CABG.|OTHER: Valve Repair Procedure with CABG.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Metformin and Omega-3 Fatty Acids in Woman With a History of Early Stage Breast Cancer
Status: COMPLETED
Conditions: Stage 0 Breast Carcinoma|Breast Neoplasms|Stage I Breast Carcinoma|Stage II Breast Carcinoma|Stage III Breast Carcinoma
Interventions: DRUG: Metformin|DRUG: Omega-3 fatty acids
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Avastin (Bevacizumab) in Combination With Standard Chemotherapy in Children and Adolescents With Sarcoma.
Status: COMPLETED
Conditions: Sarcoma
Interventions: DRUG: Standard chemotherapy|DRUG: bevacizumab [Avastin]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Incorporation of Patient and Family to Attention and Care Program in Oncology Versus Standard of Care
Status: COMPLETED
Conditions: Lung Neoplasms
Interventions: BEHAVIORAL: Early allocation to palliative care|BEHAVIORAL: Nutritional counseling|BEHAVIORAL: Psychoeducation.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The COMPLETE Treatment of Bifurcation With Two-stent Techniques: Randomized Comparison of Crush Versus Culotte Technique
Status: RECRUITING
Conditions: Coronary Artery Disease
Interventions: DEVICE: Crush technique|DEVICE: Culotte technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Viewpoints on the Social Representations and Rationale Concerning the Choices of Patients, Doctors and Caregivers With Regard to the Management of Patients With Non-resectable Metastatic Cancer of the Colon, Stomach, Bile Ducts, Rectum, Pancreas or Lung, or Gastrointestinal Neuroendocrine Tumours
Status: TERMINATED
Conditions: Non-resectable Metastatic Cancer of the Lung|Non-resectable Metastatic Cancer of the Colon|Non-resectable Metastatic Cancer of the Rectosigmoid Junction|Non-resectable Metastatic Cancer of the Stomach|Non-resectable Metastatic Cancer of the Bile Duct|Non-resectable Metastatic Cancer of the Rectum|Non-resectable Metastatic Cancer of Gastrointestinal Neuroendocrine Tumour|Non-resecable Metastatic Cancer of the Pancreas
Interventions: OTHER: Interviews|OTHER: Questionnaires
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: AIIM Trial: Personalized Medicine Approach to Kidney Allograft Function
Status: NOT_YET_RECRUITING
Conditions: Kidney Transplant Rejection
Interventions: OTHER: Phenotypic Personalized Medicine Dosing|OTHER: Standard of Care Dosing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Supervised Online Resistance Training vs Unsupervised Self-administered Resistance Training for Elders
Status: ACTIVE_NOT_RECRUITING
Conditions: Healthy Aging
Interventions: BEHAVIORAL: Supervised team-based exercise|BEHAVIORAL: Unsupervised exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study Comparing Sirolimus/Prograf vs Sirolimus/CsA in High-Risk Renal Transplant Recipients
Status: COMPLETED
Conditions: Renal Allograft Recipients
Interventions: DRUG: Rapamune
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Use of Transcutaneous Posterior Tibial Nerve Stimulation (TPTNS) in Maintaining OAB Symptoms Improvement.
Status: COMPLETED
Conditions: Overactive Bladder
Interventions: DEVICE: Transcutaneous Stimulation|PROCEDURE: Percutaneus Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Safety and Dose-Determining Study of CMX001 In Infants With Neonatal Herpes Simplex Virus (HSV) Infection Involving the Central Nervous System (CNS Disease)
Status: WITHDRAWN
Conditions: Herpes Simplex Virus
Interventions: DRUG: Novel Antiviral Drug|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: to Evaluate Effect of Multi Doses Flibans 100 mg Film-c Tablets on Single Dose PK of Digoxin 0.5 mg, Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Flibanserin plus Digoxin|DRUG: Digoxin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preventing Bed-rest Induced Muscle Loss in the Elderly
Status: COMPLETED
Conditions: Muscle Loss|Disuse Atrophy|Protein Metabolism|Prehabilitation|Sarcopenia
Interventions: OTHER: Resistance exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of Two Insertion Technique of I-gel
Status: UNKNOWN
Conditions: Prostate Cancer|Prostate Tumor|Bladder Cancer|Bladder Tumor
Interventions: PROCEDURE: Rotational technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: RCT of Steroids Following Kasai Portoenterostomy for Biliary Atresia.
Status: UNKNOWN
Conditions: Biliary Atresia
Interventions: DRUG: prednisolone|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dose Escalation of Interleukin-1 (IL-7) Added on Antiviral Treatment and Vaccination in HBeAg-negative Chronic Hepatitis B Virus (HBV) Infected Patients
Status: UNKNOWN
Conditions: Chronic Hepatitis B
Interventions: DRUG: CYT107+GenHevac+entecavir or tenofovir|DRUG: CYT107+ entecavir or tenofovir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Comparing Inotuzumab Ozogamicin In Combination With Rituximab Versus Defined Investigator's Choice In Follicular Non-Hodgkin's Lymphoma (NHL)
Status: TERMINATED
Conditions: Lymphoma, Follicular
Interventions: DRUG: inotuzumab ozogamicin|DRUG: rituximab|DRUG: rituximab|DRUG: cyclophosphamide|DRUG: vincristine|DRUG: prednisone/prednisolone|DRUG: mitoxantrone|DRUG: fludarabine|DRUG: dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Feasibility Study of the Use of the gekoTM Device for Faecal Incontinence in Older People Living at Home or in Care Homes
Status: COMPLETED
Conditions: Fecal Incontinence
Interventions: DEVICE: geko(TM) device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Change on Sleep Quality of Patients With Fibromyalgia Subjected to a Protocol Based on Physical Exercise and Stretching
Status: COMPLETED
Conditions: Fibromyalgia|Sleep|Stretch
Interventions: PROCEDURE: Muscle Stretching|PROCEDURE: Physical Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of ADX-102 in Subjects With Allergic Conjunctivitis
Status: COMPLETED
Conditions: Conjunctivitis, Allergic
Interventions: DRUG: ADX-102 Ophthalmic Drops (0.5%)|DRUG: ADX-102 Ophthalmic Drops (0.1%)|DRUG: Vehicle of ADX-102 Ophthalmic Drops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Two Different Doses of BI 1026706 on the Overall Peak-to-Peak (PtP) N2/P2-component Amplitude of Laser (Somatosensory, Radiant-heat) Evoked Potentials (LEP) in UVB(Ultraviolet)-Irradiated Skin in Healthy Male Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Placebo to BI 1026706|DRUG: Pregabalin|DRUG: BI 1026706|DRUG: Celecoxib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Schizophrenia, Related Troubles and Glutathione: Clinical Trial. Effects of Oral Administration of N-Acetylcysteine (NAC) on the Brain Glutathione Level and on the Symptoms of Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: N-Acetyl-Cysteine (NAC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Hard and Soft Tissue Maintenance Around Implants With a Sloped Configuration
Status: RECRUITING
Conditions: Tooth Loss
Interventions: DEVICE: Astra Tech Implant System Profile EV|DEVICE: Astra Tech Implant System EV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Investigational Scan (MRI With Dixon Based Sequences) in Detecting Prostate Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Carcinoma
Interventions: PROCEDURE: Dixon MRI|PROCEDURE: Magnetic Resonance Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Randomized Trial Comparing Epiretinal Membrane Surgery With and Without Internal Limiting Membrane Removal
Status: TERMINATED
Conditions: Epiretinal Membrane
Interventions: PROCEDURE: Pars plana vitrectomy and epiretinal membrane peel|PROCEDURE: ILM peel assisted by ICG|PROCEDURE: CE-IOL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Dexmedetomidine and Meperidine for the Prevention of Shivering Following Coronary Artery Bypass Graft
Status: UNKNOWN
Conditions: Coronary Artery Disease|Postoperative Shivering
Interventions: DRUG: Dexmedetomidine|DRUG: Meperidine|DRUG: Placeb
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effects of a Single Session of Rhythmic Movement Program on Selected Biopsychological Parameters in PD Patients
Status: NOT_YET_RECRUITING
Conditions: Parkinson Disease|Rhythm
Interventions: OTHER: Musicokinetic Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Self-Advocacy Serious Game in Advanced Cancer
Status: COMPLETED
Conditions: Ovarian Cancer Stage III|Ovarian Cancer Stage IV|Breast Cancer Stage IV|Cervical Cancer Stage IIIB|Cervical Cancer Stage IVA|Cervical Cancer Stage IVB|Endometrial Cancer Stage III|Endometrial Cancer Stage IV|Vulvar Cancer, Stage III|Vulvar Cancer, Stage IV|Vaginal Cancer Stage III|Vaginal Cancer Stage IVA|Vaginal Cancer Stage IVB
Interventions: BEHAVIORAL: Strong Together serious game
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Histaminergic Basis of Central Fatigue in Multiple Sclerosis - A Novel Approach
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DRUG: Carbidopa|DIETARY_SUPPLEMENT: L-Histidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tabelecleucel for Solid Organ or Allogeneic Hematopoietic Cell Transplant Participants With Epstein-Barr Virus-Associated Post-Transplant Lymphoproliferative Disease (EBV+ PTLD) After Failure of Rituximab or Rituximab and Chemotherapy
Status: RECRUITING
Conditions: Epstein-Barr Virus+ Associated Post-transplant Lymphoproliferative Disease (EBV+ PTLD)|Solid Organ Transplant Complications|Lymphoproliferative Disorders|Allogeneic Hematopoietic Cell Transplant|Stem Cell Transplant Complications
Interventions: BIOLOGICAL: tabelecleucel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High Dose and Low Dose of Atorvastatin in Patients With Unstable Angina and NSTEMI (Non ST Elevation MI)
Status: COMPLETED
Conditions: Cardiovascular Disease
Interventions: DRUG: Low dose Atorvastatin|DRUG: High dose atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pemetrexed and Carboplatin in Locally Advanced or Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer|Neoplasm Metastasis
Interventions: DRUG: Pemetrexed|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety, Tolerability, Pharmacokinetics (PK) and Target Engagement (TE) Study of GSK3858279 in Healthy Participants and Evaluation of the Efficacy of Repeat Doses in Participants With Osteoarthritis (OA)
Status: COMPLETED
Conditions: Pain, Inflammatory
Interventions: DRUG: GSK3858279 IV|DRUG: GSK3858279 SC|DRUG: Placebo matching to GSK3858279 (SC or IV)|DRUG: Placebo matching to GSK3858279 (SC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Combined Ultrasound-guided Subdeltoid Corticosteroid Injections and Physiotherapy in Treatment of Patients With Chronic Subacromial Bursitis
Status: COMPLETED
Conditions: Subacromial Bursitis|Subacromial Impingement Syndrome|Physical Therapy|Therapeutic Exercise|Rehabilitation
Interventions: DRUG: Triamcinolone SASD injection|PROCEDURE: Physiotherapy|DRUG: Triamcinolone injections & Physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: In.Pact Flexion, Investigating the Performance of the In.Pact Admiral DEB for Popliteal Lesions
Status: UNKNOWN
Conditions: Peripheral Arterial Disease
Interventions: DEVICE: InPact Admiral DEB
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bemiparin Versus Enoxaparin in the Prevention of Venous Thromboembolism Among ICU Patients
Status: COMPLETED
Conditions: Venous Thromboembolism
Interventions: DRUG: Enoxaparin|DRUG: Bemiparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Brain Stimulation During a Daytime Nap on Memory Consolidation in Patients With Mild Cognitive Impairment
Status: COMPLETED
Conditions: Mild Cognitive Impairment, So Stated
Interventions: DEVICE: SHAM stimulation|DEVICE: 0,75 Hz stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Using IT to Improve Access, Communication and Asthma in African American and Hispanic/Latino Adults
Status: COMPLETED
Conditions: Asthma|Communication
Interventions: BEHAVIORAL: Portal training and home visits|BEHAVIORAL: Portal training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effects of Nitroglycerin Versus Labetalol on Tissue Perfusion During Deliberate Hypotension
Status: COMPLETED
Conditions: Tissue Perfusion|Deliberate Hypotension|Sinus Endoscopic Surgery
Interventions: DRUG: Nitroglycerin|DRUG: Labetalol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Anti-CD33 CAR-T Cells for the Treatment of Relapsed/Refractory CD33+ Acute Myeloid Leukemia
Status: UNKNOWN
Conditions: Relapsed and/or Refractory Acute Myeloid Leukemia|High Risk Hematologic Malignancies
Interventions: BIOLOGICAL: anti-CD33 CAR T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Incremental Clomiphene Citrate Doses in Successive Cycles and FSH, LH and Steroid Hormone Levels
Status: COMPLETED
Conditions: Unexplained Infertility|Ovulation Disorder
Interventions: DRUG: Clomiphene Citrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Umbilical Cord Mesenchymal Stem Cells Injection for Diabetic Foot
Status: UNKNOWN
Conditions: Diabetic Foot|Critical Limb Ischemia|Mesenchymal Stem Cells|Umbilical Cord
Interventions: BIOLOGICAL: umbilical cord mesenchymal stem cells|DRUG: Standard Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Proprioceptive Knee Braces on the Performance and Endurance of Recreational Soccer Players Aged 60-80 Years
Status: RECRUITING
Conditions: Healthy Volunteers
Interventions: DEVICE: proprioceptive knee braces|DEVICE: No knee brace
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Case-Cohort Study of Hematopoietic Malignancies and Related Disorders and Lung Cancer in Benzene-Exposed Workers in China
Status: COMPLETED
Conditions: Lung Cancer|Lymphoma|Acute Non-Lymphocytic Leukemia|Benzene Poisoning|Leukemia
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Catheter Evaluation for Endocardial Ablation in Patients With Typical Atrial Flutter
Status: COMPLETED
Conditions: Atrial Flutter
Interventions: DEVICE: RF energy delivery for treatment of Typical Atrial flutter
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PD-1 Alone or With Dendritic Cell/Renal Cell Carcinoma Fusion Cell Vaccine
Status: TERMINATED
Conditions: Renal Cell Carcinoma
Interventions: DRUG: CT-011|BIOLOGICAL: DC/RCC fusion vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Autologous Cultured Myoblasts (BioWhittaker) Transplanted Via Myocardial Injection
Status: UNKNOWN
Conditions: Congestive Heart Failure|Coronary Artery Disease|Myocardial Infarction
Interventions: DRUG: MyoCell™ Autologous Myoblasts
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Hyperglycemia on Myocardial Perfusion in Humans With and Without Type 2 Diabetes
Status: COMPLETED
Conditions: Coronary Artery Disease|Diabetes Mellitus Type 2
Interventions: DRUG: Glucagon-Like-Peptide-1/Regadenoson/Perflutren Lipid Microsphere
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Prospective Study of Acute Cardiovascular Effects of First-line Sunitinib in Metastatic Renal Cell Carcinoma Patients (SUnitinib Prospective CardiovasculaR Effect)
Status: COMPLETED
Conditions: Renal Cell Carcinoma|Cardiotoxicity|Heart Failure|Hypertension
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Tocotrienol and Bevacizumab in Metastatic Colorectal Cancer
Status: RECRUITING
Conditions: Colorectal Cancer Metastatic
Interventions: DRUG: Fluorouracil|DRUG: Calcium folinate|DRUG: Oxaliplatin|DRUG: Bevacizumab|DRUG: Capecitabine|DIETARY_SUPPLEMENT: Tocotrienol|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of SA4Ag Vaccine in Adults Having Elective Open Posterior Spinal Fusion Procedures With Multilevel Instrumentation
Status: TERMINATED
Conditions: Staphylococcal Vaccine
Interventions: BIOLOGICAL: Staphylococcus aureus 4-Antigen (SA4Ag) Vaccine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Hall Technique or Modified Hall Technique of Deep Carious Lesions in Primary Molars
Status: ACTIVE_NOT_RECRUITING
Conditions: Dental Caries in Children|Tooth Diseases|Tooth Demineralization|Stomatognathic Diseases
Interventions: PROCEDURE: Hall Technique|PROCEDURE: Modified Hall Technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Daxdilimab (HZN-7734) in Participants With Active Proliferative Lupus Nephritis (LN)
Status: TERMINATED
Conditions: Lupus Nephritis
Interventions: DRUG: Daxdilimab|DRUG: Daxdilimab|DRUG: Placebo (Normal Saline)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pembrolizumab and Combination Chemotherapy in Treating Patients With Previously Untreated Diffuse Large B-cell Lymphoma or Grade 3b Follicular Lymphoma
Status: COMPLETED
Conditions: Composite Lymphoma|Grade 3b Follicular Lymphoma|Stage I Diffuse Large B-Cell Lymphoma|Stage I Follicular Lymphoma|Stage II Diffuse Large B-Cell Lymphoma|Stage II Follicular Lymphoma|Stage III Diffuse Large B-Cell Lymphoma|Stage III Follicular Lymphoma|Stage IV Diffuse Large B-Cell Lymphoma|Stage IV Follicular Lymphoma
Interventions: DRUG: Cyclophosphamide|DRUG: Doxorubicin Hydrochloride|OTHER: Laboratory Biomarker Analysis|BIOLOGICAL: Pembrolizumab|DRUG: Prednisone|BIOLOGICAL: Rituximab|DRUG: Vincristine Sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Breast Reconstruction and Augmentation With Brava Enhanced Autologous Fat Micro Grafting
Status: COMPLETED
Conditions: Mammaplasty|Mastectomy|Lumpectomy
Interventions: DEVICE: Brava Autologous Fat Transfer System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Carfilzomib, Daratumumab, Lenalidomide and Dexamethasone as First Line Treatment in Multiple Myeloma
Status: WITHDRAWN
Conditions: Multiple Myeloma
Interventions: DRUG: Daratumumab Only Product in Parenteral Dose Form
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oncolytic HSV-1716 in Treating Younger Patients With Refractory or Recurrent High Grade Glioma That Can Be Removed By Surgery
Status: TERMINATED
Conditions: Recurrent Childhood Anaplastic Astrocytoma|Recurrent Childhood Anaplastic Oligoastrocytoma|Recurrent Childhood Anaplastic Oligodendroglioma|Recurrent Childhood Giant Cell Glioblastoma|Recurrent Childhood Glioblastoma|Recurrent Childhood Gliomatosis Cerebri|Recurrent Childhood Gliosarcoma
Interventions: BIOLOGICAL: oncolytic HSV-1716|DRUG: dexamethasone|PROCEDURE: therapeutic conventional surgery|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Research Study Looking at How NNC0385-0434 Tablets Work to Lower Blood Cholesterol in People With Heart Disease or a High Risk of Heart Disease
Status: COMPLETED
Conditions: Atherosclerotic Cardiovascular Disease
Interventions: DRUG: NNC0385-0434 A 15 mg|DRUG: NNC0385-0434 A 40 mg|OTHER: Placebo I A (for NNC0385-0434 A 15 mg)|DRUG: NNC0385-0434 A 100 mg|OTHER: Placebo I A (for NNC0385-0434 A 40 mg)|OTHER: Placebo II A (for NNC0385-0434 A 100 mg)|DRUG: Evolocumab 140 mg/mL, Repatha®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Ureteral Stent-related Pain and Mirabegron (SPAM) Trial
Status: COMPLETED
Conditions: Nephrolithiasis
Interventions: DRUG: Mirabegron|DRUG: Tamsulosin|DRUG: Tylenol #3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hematopoietic Stem Cell Transplantation in the Treatment of Infant Leukemia
Status: ACTIVE_NOT_RECRUITING
Conditions: Leukemia|Myelodysplastic Syndromes|Childhood Acute Myeloid Leukemia in Remission|Recurrent Childhood Acute Myeloid Leukemia|Secondary Acute Myeloid Leukemia|Childhood Acute Lymphoblastic Leukemia in Remission|Previously Treated Myelodysplastic Syndrome|Secondary Myelodysplastic Syndrome|Refractory Anemia With Excess Blasts in Transformation|Refractory Anemia With Excess Blasts|Refractory Anemia|De Novo Myelodysplastic Syndrome|Childhood Myelodysplastic Syndrome
Interventions: BIOLOGICAL: filgrastim|DRUG: busulfan|DRUG: cyclosporine|DRUG: fludarabine phosphate|DRUG: melphalan|DRUG: mycophenolate mofetil|PROCEDURE: umbilical cord blood transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Changes in Sensitivity, Taste and Smell in Stroke Patients
Status: RECRUITING
Conditions: Dysphagia|Stroke
Interventions: DIAGNOSTIC_TEST: FEES (flexible endoscopic evaluation of swallowing)|OTHER: Sensitivity threshold|DIAGNOSTIC_TEST: Taste-/smell-test|DIAGNOSTIC_TEST: Neuropsychological testing
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Nervous System Manipulation and Botanicals for the Treatment of Recurrent Ear Infections in Children
Status: COMPLETED
Conditions: Otitis Media
Interventions: PROCEDURE: Craniosacral Osteopathic Manipulative Treatment|DRUG: Botanicals
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Compassionate Use of CORLUX® (Mifepristone) in the Treatment of Signs and Symptoms of Endogenous Cushing's Syndrome
Status: COMPLETED
Conditions: Cushing's Disease|Cushing's Syndrome
Interventions: DRUG: Mifepristone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Pain After Intra-articular Botulinum Toxin Injections in Carpometacarpal Osteoarthritis of the Thumb
Status: RECRUITING
Conditions: Rhizarthrosis
Interventions: DRUG: Botulinum toxin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cabergoline Combined Hydroxychloroquine/Chloroquine to Treat Resistant Prolactinomas
Status: UNKNOWN
Conditions: Resistance, Disease|Prolactinoma
Interventions: DRUG: HCQ/CQ and CAB combined treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HVPG-guided Laparoscopic Versus Endoscopic Therapy for Variceal Rebleeding in Portal Hypertension: A Multicenter Randomized Controlled Trial (CHESS1803)
Status: UNKNOWN
Conditions: Portal Hypertension|Variceal Rebleeding
Interventions: DRUG: Propranolol|PROCEDURE: Laparoscopic splenectomy and pericardial devascularization|PROCEDURE: Endoscopic therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Drug Interaction Study With Rifampicin and Afatinib
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Afatinib|DRUG: Afatinib|DRUG: Rifampicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Secret Trail of Moon (Serious Videogame) and Chess on ADHD: a Clinal Trial
Status: UNKNOWN
Conditions: Attention Deficit Disorder With Hyperactivity
Interventions: BEHAVIORAL: Cognitive Traning with The Secret Trail of Moon|BEHAVIORAL: Cognitive Traning with Therapeutic Chess|DRUG: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Copper Cu 64 TP3805 PET in Detecting Cancer in Patients With Prostate Cancer Undergoing Surgery
Status: COMPLETED
Conditions: Prostate Adenocarcinoma|Stage IIB Prostate Cancer|Stage III Prostate Cancer|Stage IV Prostate Cancer
Interventions: RADIATION: Copper Cu 64 TP3805|PROCEDURE: Positron Emission Tomography|PROCEDURE: Computed Tomography|PROCEDURE: Radical Prostatectomy|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Speckle Tracking Echocardiography as a Tool for Early Diagnosis of Impaired Fetal Growth Twin Pregnancies
Status: RECRUITING
Conditions: Fetal Growth Restriction|Cardiac Remodeling, Ventricular|Placental Insufficiency|Air Pollution
Interventions: OTHER: sample collection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: "Principle Test" for Isolation and Characterization of Circulating Cancer Cells (CTC)-CXCR4+.
Status: ACTIVE_NOT_RECRUITING
Conditions: Neoplasm Malignant
Interventions: DEVICE: CLG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Interrupting HIV and TB Stigma in the Household in Uganda
Status: COMPLETED
Conditions: Hiv|Tuberculosis|Social Behavior|Stigma, Social|Stigmatization
Interventions: BEHAVIORAL: Social Support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Traumatic Long-term Memory of Pain in Humans
Status: RECRUITING
Conditions: Pain|Traumatic Memory
Interventions: OTHER: Validation of virtual environment and auditive stimulation with virtual reality glasses (Pilot phase)|OTHER: Electrical cutaneous stimulation and auditive stimulation (Principal Experimental phase)|OTHER: Electrical cutaneous stimulation and auditive stimulation (Secondary Experimental phase)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Colorectal Anastomosis Outcomes Using the Novel Powered Circular Stapler Compared With Manual Circular Staplers.
Status: RECRUITING
Conditions: Colorectal Anastomosis
Interventions: DEVICE: Echelon Circular™ Powered Stapler|DEVICE: 2-row circular staplers manual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: KRT-232 Compared to Ruxolitinib in Patients With Phlebotomy-Dependent Polycythemia Vera
Status: UNKNOWN
Conditions: Polycythemia Vera
Interventions: DRUG: KRT-232|DRUG: Ruxolitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Pharmacokinetics of Ceftaroline in End Stage Renal Disease Patients and Matched Healthy Subjects
Status: COMPLETED
Conditions: Renal Disease
Interventions: DRUG: 200 mg Ceftaroline fosamil|DRUG: 600 mg Ceftaroline fosamil
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of Investigational Drug CFI-402257 in Patients With Advanced Solid Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Solid Cancers|Breast Cancer
Interventions: DRUG: CFI-402257|DRUG: Fulvestrant
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Role of Lung Ultrasonography in Diagnosing Atelectasis in Robotic Pelvic Surgeries
Status: COMPLETED
Conditions: Atelectasis
Interventions: DIAGNOSTIC_TEST: Lung Ultrasonography (Baseline)|DIAGNOSTIC_TEST: Lung Ultrasonography ( At the end of surgery)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Docetaxel and Imatinib Mesylate in Treating Patients With Locally Advanced or Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: docetaxel|DRUG: imatinib mesylate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: LV20.19 CAR T-Cells in Combination With Pirtobrutinib for Relapsed, Refractory B-cell Malignancies
Status: NOT_YET_RECRUITING
Conditions: Non Hodgkin Lymphoma|Diffuse Large B Cell Lymphoma|Follicular Lymphoma|Marginal Zone Lymphoma|Mantle Cell Lymphoma|Burkitt Lymphoma
Interventions: DRUG: Pirtobrutinib|DRUG: LV20.19 CAR T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Benefit of Immunoprophylaxis on Fibrosis to Reduce Viral Load After Liver Transplantation
Status: COMPLETED
Conditions: Liver Transplantation
Interventions: DRUG: tacrolimus|DRUG: tacrolimus, ATG|DRUG: ATG+mycophénolate mofétil+tacrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Construction and Effect Evaluation of the Low Load Blood Flow Restriction Training Program for Lung Cancer Patients Complicated With Sarcopenia During Chemotherapy
Status: COMPLETED
Conditions: Sarcopenia|Lung Neoplasms
Interventions: BEHAVIORAL: Low load blood flow restriction training|BEHAVIORAL: Progressive resistance training group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Single Arm Pilot Study of Azacitidine in Myelodysplastic Syndromes (MDS) / Acute Myeloid Leukaemia (AML), With Eltrombopag Support for Thrombocytopenia
Status: COMPLETED
Conditions: Myelodysplastic Syndromes (MDS)|Acute Myeloid Leukaemia (AML)
Interventions: DRUG: Azacitidine and eltrombopag
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Comparing Outcomes for Patients With Treatment Resistant Depression Who Receive VNS Therapy at Different Doses
Status: COMPLETED
Conditions: Depression
Interventions: DEVICE: VNS Therapy|DEVICE: VNS Therapy|DEVICE: VNS Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Radiotherapy Dose Adaptation Based on Tumor Biology in Patients With cN2b-N3 Breast Cancer
Status: RECRUITING
Conditions: Breast Cancer Stage III
Interventions: RADIATION: Whole breast / chest wall & regional lymph node irradiation|RADIATION: Internal mammary or supraclavicular lymph node boost
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fractionated Carbon Dioxide Laser Therapy for Treatment of Peyronie's Disease
Status: COMPLETED
Conditions: Peyronies Disease
Interventions: DEVICE: Fractional Carbon Dioxide Laser Therapy at 10-15% Laser Density Coverage
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of CJ-15314 Phosphate in Healthy Male Subjects
Status: UNKNOWN
Conditions: Healthy
Interventions: DRUG: A dose as CJ-15314|DRUG: B dose as CJ-15314|DRUG: C dose as CJ-15314|DRUG: D dose as CJ-15314|DRUG: E dose as CJ-15314|DRUG: F dose as CJ-15314|DRUG: Placebo|DRUG: Placebo|DRUG: Placebo|DRUG: Placebo|DRUG: Placebo|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nutrition, Immunity, and Covid-19 in Obese People
Status: COMPLETED
Conditions: Vitamin D Deficiency|Covid19|Overweight and Obesity|Immune Deficiency
Interventions: DIETARY_SUPPLEMENT: Probiotics, Vitamin D|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: RETAIN: Retaining Opioid Users Entering Medication Assisted Treatment and Encouraging HCV/HIV Testing
Status: COMPLETED
Conditions: Opioid-Related Disorders|Opioid-use Disorder|Drug Addiction|Substance Use Disorders
Interventions: OTHER: self-administered, e-health application
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Up-front Hematopoietic Stem Cell Transplantation in Acute Myeloid Leukemia Patients Aged 65-75
Status: COMPLETED
Conditions: Acute Myeloid Leukemia, Adult
Interventions: DRUG: Up-front allogeneic hematopoietic stem cell transplantation (HSCT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Validation of Algorithms for Basal Insulin Rate Reductions in Type 1 Diabetic Patients Practising Physical Activity
Status: COMPLETED
Conditions: Type 1 Diabetes With a Subcutaneous Insulin Pump|Adjustment of the Recommended Basal Insulin Flow Rate in the Event of Physical Activity|Adjustment of the Recommended Prandial Insulin in the Event of Physical Activity
Interventions: OTHER: 50%VO2maxTBR50|OTHER: 50%VO2max TBR80|OTHER: 75%VO2max TBR80|OTHER: 75%VO2max TBR100|OTHER: Rest
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Release Kinetics of rhBMP-2 Using E-PRF as an Autologous Carrier: An In Vitro Analysis
Status: NOT_YET_RECRUITING
Conditions: Bone Loss
Interventions: BIOLOGICAL: E-PRF/rhBMP-2 (similar ratios)|BIOLOGICAL: E-PRF/ACS/rhBMP-2|BIOLOGICAL: rhBMP-2/E-PRF|BIOLOGICAL: E-PRF only
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p