pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Diagnosis and Management of Myofascial Pain Syndrome in Women With Mastectomies
Status: UNKNOWN
Conditions: Breast Cancer|Myofascial Trigger Point
Interventions: OTHER: Kinesiotherapy|OTHER: Isquemic compression|OTHER: High voltage electrical stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Multiple-dose Study of LY3031207 in Healthy Participants
Status: TERMINATED
Conditions: Healthy Volunteers
Interventions: DRUG: Placebo|DRUG: LY3031207|DRUG: Celecoxib|DRUG: Simvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of YM178 in Subjects With Symptoms of Overactive Bladder
Status: COMPLETED
Conditions: Urinary Bladder, Overactive
Interventions: DRUG: YM178|DRUG: Placebo|DRUG: tolterodine ER
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics and Drug Interaction Study Between Rosuvastatin and CS-866 in Healthy Male Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Cresto|DRUG: Olmetec|DRUG: Cresto, Olmetec
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: A Study of Dual-SIgnaling Protein 107 (DSP107) for Patients With Hematological Malignancies
Status: RECRUITING
Conditions: Acute Myeloid Leukemia|Myelodysplastic Syndromes|Chronic Myelomonocytic Leukemia
Interventions: BIOLOGICAL: DSP107|DRUG: Azacitidine|DRUG: Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CAR-T Hepatic Artery Infusions and Sir-Spheres for Liver Metastases
Status: COMPLETED
Conditions: Liver Metastases
Interventions: BIOLOGICAL: anti-CEA CAR-T cells|DEVICE: Sir-Spheres
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Alendronate Prevents Microarchitectural Deterioration of Trabecular Bone in Early Postmenopausal Women
Status: COMPLETED
Conditions: Osteopenia|Osteoporosis
Interventions: DRUG: alendronate sodium|OTHER: placebo comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Tolerability of Oral OPC-34712 as Adjunctive Therapy in Adults With Major Depressive Disorder (the Orion Trial)
Status: COMPLETED
Conditions: Depressive Disorder|Depression|Depressive Disorder, Major|Mood Disorders|Mental Disorders
Interventions: DRUG: OPC-34712|DRUG: Escitalopram|DRUG: Fluoxetine|DRUG: Paroxetine CR|DRUG: Sertraline|DRUG: Duloxetine|DRUG: Venlafaxine XR
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Success of Tocilizumab in RA Patients With Remission Induction and Sustained Efficacy After Discontinuation
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Tocilizumab plus methotrexate|DRUG: Tocilizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Using a Stress Ball During Vaginal Examination on Anxiety and Pain Levels: A Randomized Controlled Study
Status: NOT_YET_RECRUITING
Conditions: Anxiety State|Pain|Exanimation
Interventions: BEHAVIORAL: Stress ball intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Adaptive Trial Scheduling in Naming Treatment for Aphasia
Status: RECRUITING
Conditions: Aphasia|Stroke
Interventions: BEHAVIORAL: Adaptive Spacing Condition|BEHAVIORAL: High-Item Non-Adaptive Spacing Condition|BEHAVIORAL: Low-Item Non-Adaptive Spacing Condition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: IV Iron vs Oral Iron for Treatment of Anemia in Women With Abnormal Uterine Bleeding
Status: RECRUITING
Conditions: Anemia, Iron Deficiency|Heavy Menstrual Bleeding
Interventions: DRUG: Ferumoxytol|DRUG: Ferrous Sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The AP-GELP Study: A Clinical Trial on the Effects of Apremilast in Female Genital Erosive Lichen Planus
Status: ACTIVE_NOT_RECRUITING
Conditions: Lichen Planus of Vulva|Female Genital Disease
Interventions: DRUG: Apremilast|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Endoscopic Ultrasound-guided Fine Needle Biopsy With 25-gauge Biopsy Needles for Solid Pancreatic Masses
Status: COMPLETED
Conditions: Solid Pancreatic Masses
Interventions: DEVICE: EUS-FNB with 25-gauge (Echotip ProCore; Cook Endoscopy Inc, Limerick, Ireland)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Colon Cleansing Efficacy With 1L vs. 2L vs. 4L-PEG for Colonoscopy Among Inpatients
Status: UNKNOWN
Conditions: Colon Disease
Interventions: DRUG: NER1006|DRUG: MoviPrep|DRUG: Macrogol 400
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Benralizumab in Atopic Dermatitis
Status: COMPLETED
Conditions: Dermatitis, Atopic|Dermatitis|Eczema|Skin Diseases|Skin Diseases, Genetic|Genetic Diseases, Inborn|Skin Diseases, Eczematous|Hypersensitivity|Hypersensitivity, Immediate|Immune System Diseases
Interventions: DRUG: Benralizumab|DRUG: Placebo Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cryoablation Combined With Tislelizumab Plus Lenvatinib in Patients With Melanoma Liver Metastasis
Status: RECRUITING
Conditions: Melanoma
Interventions: DRUG: Tislelizumab|DRUG: Lenvatinib|DRUG: Cryoablation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Natural Killer(NK) Cell Therapy for Acute Myeloid Leukemia
Status: RECRUITING
Conditions: AML, Adult
Interventions: DRUG: QN-023a|DRUG: Cyclophosphamid|DRUG: Fludarabine|DRUG: Cytarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: FTIH to Evaluate Safety, Tolerability, and Pharmacokinetics of Single Oral Doses of GSK1322888 in Healthy Caucasian and Japanese Volunteers
Status: COMPLETED
Conditions: Gastroparesis
Interventions: DRUG: GSK1322888|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Cixutumumab and Sorafenib Tosylate in Treating Patients With Advanced Liver Cancer
Status: COMPLETED
Conditions: Adult Hepatocellular Carcinoma|Advanced Adult Hepatocellular Carcinoma|Localized Non-Resectable Adult Liver Carcinoma|Recurrent Adult Liver Carcinoma
Interventions: BIOLOGICAL: Cixutumumab|OTHER: Laboratory Biomarker Analysis|DRUG: Sorafenib Tosylate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Enhanced Recovery After Surgery (ERAS) Pathway in Patients Undergoing Robot-Assisted Laparoscopic Radical Prostatectomy
Status: NOT_YET_RECRUITING
Conditions: Prostate Cancer|Prostatectomy|Enhanced Recovery After Surgery|Prehabilitation|Length of Hospital Stay
Interventions: PROCEDURE: Routine care|PROCEDURE: ERAS management pathway
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Doxorubicin and Cyclophosphamide Followed By Trastuzumab, Paclitaxel, and Lapatinib in Treating Patients With Early-Stage HER2-Positive Breast Cancer That Has Been Removed By Surgery
Status: COMPLETED
Conditions: Breast Cancer|Cardiac Toxicity
Interventions: BIOLOGICAL: trastuzumab|DRUG: cyclophosphamide|DRUG: doxorubicin hydrochloride|DRUG: lapatinib ditosylate|DRUG: paclitaxel|GENETIC: gene expression analysis|GENETIC: reverse transcriptase-polymerase chain reaction|OTHER: fluorophotometry|OTHER: laboratory biomarker analysis|OTHER: mass spectrometry|PROCEDURE: adjuvant therapy|PROCEDURE: quality-of-life assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: |Primary Purpose: TREATMENT
Clinical trial: Comparative Clinical Effects of Salvadora Persica Oral Rinse And A Phenolic Commercial Mouth Wash On Human Oral Health
Status: UNKNOWN
Conditions: Plaque, Dental
Interventions: OTHER: oral rinces
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Warmed Irrigation in Hip Arthroscopy Undergoing Hip Arthroscopy
Status: COMPLETED
Conditions: Femoro Acetabular Impingement|Pain, Postoperative
Interventions: PROCEDURE: Warmed Arthroscopic Fluids|PROCEDURE: Room Temperature Arthroscopic Fluids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Measurable Residual Disease in Allo-HSCT Using Digital Polymerase Chain Reaction
Status: RECRUITING
Conditions: Acute Leukemia|MDS|MDS/MPN|CML
Interventions: DIAGNOSTIC_TEST: Digital PCR|DIAGNOSTIC_TEST: Quantitative PCR|DIAGNOSTIC_TEST: MFC
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Early Intervention in Cognitive Aging
Status: ACTIVE_NOT_RECRUITING
Conditions: Overweight, Obesity and Other Hyperalimentation (E65-E68)
Interventions: DIETARY_SUPPLEMENT: Berry fruit powder OR nutritional ketosis|DIETARY_SUPPLEMENT: Placebo powder OR higher carbohydrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Intrathecal vs Intraarticular Dexmedetomidine on Postoperative Pain Following Arthroscopy
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: Intrathecal Dexmedetomidine|DRUG: Intraarticular Dexmedetomidine|DRUG: Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Precision Nutrition and Metabolic Function
Status: RECRUITING
Conditions: Obesity|Insulin Resistance
Interventions: BEHAVIORAL: Mediterranean diet|BEHAVIORAL: Low-carbohydrate, ketogenic diet|BEHAVIORAL: Low-fat diet|OTHER: Annual follow-up testing for 5 years
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Safety & Efficacy of DC Vaccine and TMZ for the Treatment of Newly-diagnosed Glioblastoma After Surgery
Status: ACTIVE_NOT_RECRUITING
Conditions: Glioblastoma Multiforme of Brain
Interventions: BIOLOGICAL: Autologous dendritic cells pulsed with multiple neoantigen peptides.|DRUG: Temozolomide adjuvant chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Peripherally Inserted Versus Centrally Inserted Central Venous Catheters in the Neurosurgical Intensive Care Unit
Status: UNKNOWN
Conditions: Thromboses, Venous|Infection|Economic Problems
Interventions: OTHER: PICC(Peripherally inserted central catheter)|OTHER: CVC(Central venous catheter )
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Effect of Mobile Application-Based Bowel Preparation Training on the Patient's Education Whom Colonoscopy is Planned
Status: RECRUITING
Conditions: Colon Disease|Colon Cancer
Interventions: BEHAVIORAL: Mobile Application-Based Bowel Preparation Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: TAK-071 Scopolamine-Induced Cognitive Impairment Study
Status: TERMINATED
Conditions: Healthy Volunteers
Interventions: DRUG: Scopolamine|DRUG: TAK-071|DRUG: Donepezil|DRUG: Scopolamine Placebo|DRUG: TAK-071 Placebo|DRUG: Donepezil Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Meditation for NICU Moms
Status: COMPLETED
Conditions: Breast Feeding|Premature Birth|Stress|Depression, Postpartum|Anxiety|Self Efficacy|Behavior, Maternal|Insufficient Lactation
Interventions: BEHAVIORAL: Meditation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study on the Efficacy of Slow Release Insulin in Cystic Fibrosis Patients With Glucide Intolerance and Clinical Decay
Status: UNKNOWN
Conditions: Cystic Fibrosis|Glucose Intolerance
Interventions: DRUG: Insulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate Drug-Drug Interaction Between D326, D337 and CKD-828 in Healthy Subjects
Status: UNKNOWN
Conditions: Dyslipidemias|Hypertension
Interventions: DRUG: Sequence 1|DRUG: Sequence 2|DRUG: Sequence 3|DRUG: Sequence 4|DRUG: Sequence 5|DRUG: Sequence 6
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pimecrolimus Cream 1% (Elidel®) and Medicated Device Cream (EletoneTM) in the Treatment and Maintenance of Atopic Dermatitis.
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: pimecrolimus|DEVICE: topical medical device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Open Randomized Prospective Clinical Study of R-FPD Versus R-MAD Regimen in the Treatment of Primary Central Nervous System Lymphoma
Status: UNKNOWN
Conditions: Primary Central Nervous System Lymphoma
Interventions: DRUG: rituximab in combination with methotrexate, cytarabine and dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transverse Dento-skeletal Effects of Two Rapid Palatal Expansion Appliances in Cleft Lip and Palate Patients
Status: UNKNOWN
Conditions: Cleft Lip and Palate
Interventions: DEVICE: hyrax appliance|DEVICE: haas appliance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Implication of Coronary Artery Disease Burden and Pattern in Ischemia-causing Vessels With PCI
Status: COMPLETED
Conditions: Coronary Artery Disease|Myocardial Ischemia|Atherosclerosis|Percutaneous Coronary Intervention
Interventions: DEVICE: Quantitative Flow Ratio derived PPG
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study to Evaluate the Safety, Tolerability, and Antiviral Activity of Selgantolimod (Formerly GS-9688) in Viremic Adult Participants With Chronic Hepatitis B (CHB) Who Are Not Currently on Treatment
Status: COMPLETED
Conditions: Chronic Hepatitis B
Interventions: DRUG: Placebo|DRUG: Selgantolimod|DRUG: TAF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Long-term Antibody Persistence of GSK Biologicals' Meningococcal Vaccine GSK134612 in Healthy Toddlers
Status: COMPLETED
Conditions: Infections, Meningococcal
Interventions: BIOLOGICAL: Meningococcal vaccine GSK134612
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Efficacy and Safety of VX-548 for Acute Pain After a Bunionectomy
Status: COMPLETED
Conditions: Acute Pain
Interventions: DRUG: VX-548|DRUG: HB/APAP|DRUG: Placebo (matched to VX-548)|DRUG: Placebo (matched to HB/APAP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Mirabegron for Treatment of Erectile Dysfunction in Patients With LUTS Secondry to BPH: A Randomized Study
Status: UNKNOWN
Conditions: BPH|Erectile Dysfunction|Prostate Hyperplasia|Erectile Abnormalities|Prostatic Neoplasms
Interventions: DRUG: Mirabegron|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ACP Max™ PRP System for Knee Osteoarthritis: A Feasibility Trial
Status: RECRUITING
Conditions: Knee Osteoarthritis
Interventions: DEVICE: ACP Max™|DEVICE: Depo-Medrol®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Maternal Iodine Supplementation and Effects on Thyroid Function and Child Development
Status: COMPLETED
Conditions: Iodine Deficiency|Infant Development
Interventions: DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: Iodine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Siltuximab for Cytokine Release Syndrome Prophylaxis Prior to tx w/ Teclistamab in RRMM
Status: NOT_YET_RECRUITING
Conditions: Multiple Myeloma|Cytokine Release Syndrome|Refractory Multiple Myeloma|Immune Effector Cell Associated Neurotoxicity Syndrome
Interventions: DRUG: Siltuximab|DRUG: Teclistamab(FDA-approved)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Diaphragmatic Paralysis Comparison Between Local Anesthetic Volumen Doses After Interscalene Block
Status: COMPLETED
Conditions: Diaphragmatic Paralysis|Brachial Plexus Block
Interventions: PROCEDURE: Interscalene brachial plexus block|DRUG: Levobupivacaine Hydrochloride 2.5 MG/ML
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of Mitoxantrone Hydrochloride Liposome Injection in Subjects With Advanced Bone and Soft Tissue Sarcoma
Status: TERMINATED
Conditions: Unresectable or Metastatic Bone and Soft Tissue Sarcoma
Interventions: DRUG: Mitoxantrone Hydrochloride Liposome Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Advanced Platelet Rich Fibrin in Periodontal Angular Defects
Status: UNKNOWN
Conditions: Intrabony Periodontal Defect
Interventions: PROCEDURE: Advanced platelet-rich fibrin mixed with biphasic alloplast|PROCEDURE: Biphasic alloplast mixed with saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Arthroscopic Rotator Cuff Repair Performed With Intraarticular Tranexamic Acid Could it Provide Improved Visual Clarity and Less Post-operative Pain? A Prospective, Double Blind, Randomized Study of 64 Patients.
Status: COMPLETED
Conditions: Rotator Cuff Tears|Rotator Cuff Rupture|Tranexamic Acid|Shoulder Arthroscopy|Visual Clarity
Interventions: PROCEDURE: Application of Tranexamic acid in arthroscopic irrigation solution|PROCEDURE: No application of Tranexamic acid in arthroscopic irrigation solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Psoriasis Plaque Test on LEO 27989 Ointment and Calcipotriol Plus LEO 27989 Ointment in Patients With Psoriasis Vulgaris
Status: COMPLETED
Conditions: Psoriasis Vulgaris
Interventions: DRUG: LEO 27989 ointment|DRUG: Calcipotriol plus LEO 27989 ointment|DRUG: Calcipotriol ointment|DRUG: Vehicle ointment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Quadratus Luborum Block Using Bupivacaine Versus Bupivacaine-Dexamethasone in Laparoscopic Cholecystectomy
Status: COMPLETED
Conditions: Post Operative Pain
Interventions: DRUG: TQL block with saline|DRUG: TQL block with Bupivacaine|DRUG: TQL block with Bupivacaine and dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acute Bronchodilator Response of a Single Dose of Atrovent or Berotec on Top of Pharmacodynamic Steady State of Spiriva
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Tiotropium + placebo|DRUG: Tiotropium + ipratropium|DRUG: Tiotropium + fenoterol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Cancer Preventive Vaccine Nous-209 for Lynch Syndrome Patients
Status: RECRUITING
Conditions: Lynch Syndrome
Interventions: BIOLOGICAL: Adenoviral Tumor-specific Neoantigen Priming Vaccine GAd-209-FSP|PROCEDURE: Biospecimen Collection|PROCEDURE: Endoscopic Biopsy|BIOLOGICAL: MVA Tumor-specific Neoantigen Boosting Vaccine MVA-209-FSP|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Transcutaneous Spinal Cord Stimulation and Robotic Therapy
Status: COMPLETED
Conditions: Spinal Cord Injuries
Interventions: DEVICE: Active tSCS and Lokomat|DEVICE: Sham tSCS and Lokomat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Catheter Dysfunction Rate in Patients Undergoing Kidney Replacement Therapy. Evaluation of the Safety and Efficacy of Anti-reflux Valves Without Heparin Lock Solution
Status: WITHDRAWN
Conditions: Chronic Renal Failure|Haemodialysis, Haemodiafiltration, Haemofiltration|Kidney Replacement Therapy|Catheter Infection, Catheter Dysfunction, Catheter Related Bloodstream Infections
Interventions: OTHER: Anti-reflux valve for dialysis catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Liver Ablative Radiotherapy Utilising Kilovoltage Intrafraction Monitoring (KIM)
Status: ACTIVE_NOT_RECRUITING
Conditions: Liver Cancer
Interventions: DEVICE: Kilovoltage Intrafraction Monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Portable Monitoring Device, Physical Activity Motivation and Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Physical Activity|Motivation
Interventions: DEVICE: Portable monitoring device|BEHAVIORAL: Routine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: An Extension of the HORIZON Protocol Evaluating the Safety of Dimebon (Latrepirdine) in Subjects With Huntington Disease
Status: TERMINATED
Conditions: Huntington Disease
Interventions: DRUG: Dimebon (latrepirdine)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Translating Healthy Lifestyle Interventions for Cancer Survivors
Status: COMPLETED
Conditions: Diabetes Mellitus, Non-Insulin-Dependent|Breast Cancer|Endometrial Cancer
Interventions: BEHAVIORAL: Standard Behavioral Weight Change Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study of HBI-8000 With Nivolumab in Melanoma, Renal Cell Carcinoma and Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Melanoma|Renal Cell Carcinoma|Non-Small Cell Lung Cancer
Interventions: DRUG: HBI-8000 in combination with nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cyberknife Precision Radiation Delivery System for Tumors of the Spine
Status: COMPLETED
Conditions: Spinal Cord Cancer|Brain (Nervous System) Cancers
Interventions: PROCEDURE: Stereotactic radiosurgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stabilometry After Pressure Release of the Flexor Digitorum Brevis Muscle Versus a Non-emission Laser: Clinical Trial
Status: COMPLETED
Conditions: Flatfoot
Interventions: OTHER: Bilateral pressure release in Flexor Brevis Digitorum in subjects with latent trigger point|OTHER: Bilateral non emission Laser in latent trigger points of the Flexor digitorum Brevis Muscle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Intermittent Selumetinib for Uveal Melanoma
Status: COMPLETED
Conditions: Uveal Melanoma
Interventions: DRUG: Selumetinib, 100mg|DRUG: Selumetinib, 125mg|DRUG: Selumetinib, 150mg|DRUG: Selumetinib, 175mg|DRUG: Selumetinib, 200mg|DRUG: Selumetinib, 225mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Usability of the Intracochlear Catheter INCAT - a Feasibility Study
Status: NOT_YET_RECRUITING
Conditions: Hearing Loss, Sensorineural|Hearing Loss, Cochlear
Interventions: DEVICE: intracochlear catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cisplatin, Pemetrexed, and Imatinib Mesylate in Malignant Mesothelioma
Status: COMPLETED
Conditions: Mesothelioma
Interventions: DRUG: Cisplatin|DRUG: Imatinib Mesylate|DRUG: Pemetrexed|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single Locking Miniplate and Two Non-locking Miniplates in the Management of Parasymphyseal Fracture
Status: UNKNOWN
Conditions: Mandible Fracture
Interventions: PROCEDURE: 2.0 single locking miniplates
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Different Treatments for Overactive Bladder Syndrome
Status: COMPLETED
Conditions: Overactive Bladder|Overactive Bladder Syndrome|Overactive Detrusor
Interventions: OTHER: Pelvic Floor Exercise Group|OTHER: Kinesio tape|OTHER: Electrical stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Relative Bioavailability of Two Formulations of Risankizumab Following Subcutaneous Administration With Prefilled Syringes in Healthy Adult Participants
Status: NOT_YET_RECRUITING
Conditions: Healthy Volunteers
Interventions: DRUG: Risankizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Sleep and Eating Behaviours in Adolescents
Status: NOT_YET_RECRUITING
Conditions: Eating Disorders|Insomnia Disorder
Interventions: BEHAVIORAL: Sleep/eating virtual reality self-help exposure-based intervention|BEHAVIORAL: Sleep/eating self-help written materials.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PRG Combined With Autologous BMMSCs for Treatment of Diabetic Foot Ulcer
Status: UNKNOWN
Conditions: Diabetic Foot Ulcer
Interventions: BIOLOGICAL: PRG combined with BMMSCs transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Rainbow INVSENSOR00001 and Control SpHb Disposable Sensor Performance During Hemodilution
Status: COMPLETED
Conditions: Healthy
Interventions: DEVICE: INVSENSOR00001|DEVICE: Control SpHb sensor|PROCEDURE: Hemodilution
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Trial of Oral BEZ235 and BKM120 in Combination With Paclitaxel With or Without Trastuzumab
Status: COMPLETED
Conditions: Metastatic or Locally Advanced Solid Tumors
Interventions: DRUG: BEZ235 + paclitaxel|DRUG: BKM120 + paclitaxel|DRUG: BEZ235 + paclitaxel + trastuzumab|DRUG: BKM120 + paclitaxel + trastuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Desmopressin in Cardiac Surgery
Status: COMPLETED
Conditions: Hemorrhage|Blood Loss, Surgical|Postoperative Hemorrhage
Interventions: DRUG: Desmopressin (DDAVP)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Comparison of a PULSE Diet and the TLC Diet on Reproductive, Metabolic Parameters in Women With PCOS
Status: RECRUITING
Conditions: Polycystic Ovary Syndrome|Metabolic Syndrome
Interventions: DIETARY_SUPPLEMENT: Pulse-based diet|DIETARY_SUPPLEMENT: TLC diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Rivaroxaban Monotherapy After CYP2C19 Genotype Testing in Patients With Atrial Fibrillation and Percutaneous Coronary Intervention
Status: NOT_YET_RECRUITING
Conditions: Atrial Fibrillation|Coronary Artery Disease
Interventions: DRUG: Rivaroxaban
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Parenteral Glutamine on Myocardial Injury and Inflammation Biomarkers
Status: COMPLETED
Conditions: Insufficiency;Cardiac
Interventions: DIETARY_SUPPLEMENT: L-alanyl-L-glutamine dipeptide|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Nutritional PSA's on Fruit and Vegetable Consumption
Status: COMPLETED
Conditions: Fruit and Vegetable Selection in the Lunchroom|Consumption Frequency Versus Selection Frequency
Interventions: BEHAVIORAL: Commercials
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Safety and Immunogenicity of a Commercially Available Influenza Vaccine (Formulation 2006/2007) When Administered to Subjects 18 Years of Age or Older
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Surface Antigen, Inactivated, Influenza (form.2006-07)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Stenting of Renal Artery Stenosis in Coronary Artery Disease Study
Status: UNKNOWN
Conditions: Renal Artery Stenosis|Left Ventricular Hypertrophy
Interventions: PROCEDURE: stenting angioplasty plus medical therapy|DRUG: Medical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Adjustment Function of a Modified Spatz3 Adjustable Balloon (Spatz4).
Status: NOT_YET_RECRUITING
Conditions: Overweight and Obesity
Interventions: DEVICE: Spatz4 Adjustable Balloon System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transitional Care Program in Stroke Patients With Hemiplegia.
Status: RECRUITING
Conditions: Ischemic Stroke|Transitional Care|Hemiplegia
Interventions: BEHAVIORAL: Intervention group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy and Celecoxib in Treating Patients With Advanced Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DRUG: celecoxib|DRUG: docetaxel|DRUG: irinotecan hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Monopolar Radiofrequency Versus Pulsed Dye Laser for Treatment of Acne Scars
Status: COMPLETED
Conditions: Acne Atrophica
Interventions: DEVICE: Monopolar radiofrequency|DEVICE: Pulsed dye laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Treating Urological Chronic Pelvic Pain Syndrome (UCPPS) Pain
Status: TERMINATED
Conditions: Chronic Prostatitis With Chronic Pelvic Pain Syndrome
Interventions: DRUG: D-Cycloserine|DRUG: Placebo (for D-cycloserine)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tofacitinib Ointment For Chronic Plaque Psoriasis
Status: COMPLETED
Conditions: Psoriasis Vulgaris|Psoriasis
Interventions: DRUG: tofacitinib ointment 20 mg/g|DRUG: tofacitinib ointment 10 mg/g|DRUG: placebo ointment (vehicle)|DRUG: tofacitinib ointment 20 mg/g|DRUG: tofacitinib ointment 10 mg/g|DRUG: placebo ointment (vehicle)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rosiglitazone in Treating Patients With Newly Diagnosed ACTH-Secreting Pituitary Tumor (Cushing Disease)
Status: TERMINATED
Conditions: Cushing's Disease
Interventions: DRUG: rosiglitazone maleate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fiberoptic Bronchoscope of Double Lumen Tube and Single Lumen Tube in Patients With Semi-regid Neck Collar.
Status: COMPLETED
Conditions: Intubation;Difficult|Thoracic Diseases
Interventions: DEVICE: single lumen tube and bronchial blocker|DEVICE: double lumen tube
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Study Examining the Safety and Toxicity of Stereotactic Body Radiotherapy (SBRT) Followed by PCX12 Immunotherapy Delivered by Intratumoral Injection for the Treatment of Patients With Locally Advanced Pancreatic Adenocarcinoma (LAPC)
Status: NOT_YET_RECRUITING
Conditions: Pancreatic Adenocarcinoma
Interventions: DRUG: PCX-12
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Radiofrequency Neurolysis and Chemical Neurolysis of the Genicular Nerves
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: PROCEDURE: Genicular nerve radiofrequency neurolysis|PROCEDURE: Genicular nerve chemical neurolysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Characterization of Acute and Recent HIV-1 Infections in Zurich: a Long-term Observational Study
Status: RECRUITING
Conditions: HIV Infections
Interventions: DRUG: Dolutegravir|DRUG: Elvitegravir, Cobicistat, Emtricitabine, and Tenofovir Alafenamid Fumarate|DRUG: Raltegravir|DRUG: Darunavir|DRUG: Ritonavir|DRUG: Rilpivirine|DRUG: Lamivudine|DRUG: tenofovir|DRUG: Emtricitabine|DRUG: Abacavir
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testing the Combination of Cediranib and Olaparib in Comparison to Each Drug Alone or Other Chemotherapy in Recurrent Platinum-Resistant Ovarian Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Fallopian Tube Clear Cell Adenocarcinoma|Fallopian Tube Endometrioid Adenocarcinoma|Fallopian Tube Serous Adenocarcinoma|Fallopian Tube Transitional Cell Carcinoma|Fallopian Tube Undifferentiated Carcinoma|Ovarian Clear Cell Adenocarcinoma|Ovarian Endometrioid Adenocarcinoma|Ovarian Seromucinous Carcinoma|Ovarian Serous Adenocarcinoma|Ovarian Transitional Cell Carcinoma|Ovarian Undifferentiated Carcinoma|Primary Peritoneal Serous Adenocarcinoma|Recurrent Fallopian Tube Carcinoma|Recurrent Ovarian Carcinoma|Recurrent Primary Peritoneal Carcinoma
Interventions: DRUG: Cediranib|DRUG: Cediranib Maleate|PROCEDURE: Computed Tomography|PROCEDURE: Magnetic Resonance Imaging|DRUG: Olaparib|DRUG: Paclitaxel|DRUG: Pegylated Liposomal Doxorubicin Hydrochloride|OTHER: Questionnaire Administration|DRUG: Topotecan|DRUG: Topotecan Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of an Oral Hair Supplement on Hair Density, Growth, and Microbiome
Status: ACTIVE_NOT_RECRUITING
Conditions: Hair Thinning
Interventions: DIETARY_SUPPLEMENT: Oral herbal supplement|DIETARY_SUPPLEMENT: Oral placebo supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Effect of Renal Impairment on the Pharmacokinetics of Isavuconazole.
Status: COMPLETED
Conditions: Pharmacokinetics of Isavuconazole|Healthy Volunteers|Renal Impaired
Interventions: DRUG: isavuconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Levosimendan in Acute Heart Failure Following Acute Myocardial Infarction.
Status: COMPLETED
Conditions: Myocardial Infarction|Heart Failure|Cardiogenic Shock
Interventions: DRUG: levosimendan|DRUG: placebo,
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Traditional Three-incision Esophagectomy Versus Minimally Invasive Thorascopic and Laparoscopic Esophagectomy
Status: UNKNOWN
Conditions: Esophageal Cancer
Interventions: PROCEDURE: open esophagectomy|PROCEDURE: Minimally invasive esophagectomy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: MERIDIAN: A Study to Evaluate the Efficacy and Safety of Pegcetacoplan in Adults With Amyotrophic Lateral Sclerosis (ALS)
Status: TERMINATED
Conditions: Amyotrophic Lateral Sclerosis|Motor Neuron Disease
Interventions: DRUG: Pegcetacoplan (APL-2)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prefabricated Endodontic Posts: Glass Fiber Versus Titanium - A Randomized Controlled Pilot- Trial
Status: COMPLETED
Conditions: Endodontically Treated Teeth|Tooth Fractures
Interventions: DEVICE: prefabricated titanium post|DEVICE: prefabricated glass fiber reinforced composite post
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of QMF149 (Indacaterol Acetate/Mometasone Furoate) Versus Budesonide in Children From 6 to Less Than 12 Years of Age With Asthma
Status: RECRUITING
Conditions: Asthma
Interventions: DRUG: QMF149|DRUG: Budesonide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Probiotics for Modic Changes in Low Back Pain Patients
Status: COMPLETED
Conditions: Low Back Pain
Interventions: DIETARY_SUPPLEMENT: Probiotic|OTHER: Inactive capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study for the Treatment of Dry Eye in Postmenopausal Women
Status: RECRUITING
Conditions: Postmenopausal Women With DED
Interventions: DRUG: EG017 ointment|DRUG: EG017 ointment placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study to Examine the Effects of Vitamin D Supplementation on Mitochondrial Bioenergetics in Older Adults
Status: COMPLETED
Conditions: Low 25-hydroxyvitamin D Concentrations
Interventions: DIETARY_SUPPLEMENT: Vitamin D3
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Endothelial Dysfunction Evaluation for Coronary Heart Disease Risk Estimation in Rheumatoid Arthritis (EDRA Study)
Status: UNKNOWN
Conditions: Rheumatoid Arthritis|Coronary Heart Disease
Interventions: DEVICE: Endothelial Dysfunction evaluation by EndoPAT
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Capecitabine (Xeloda) and Lapatinib (Tykerb) as First-line Therapy in HER2/Neu-positive Breast Cancer
Status: TERMINATED
Conditions: Breast Cancer|Metastatic Breast Cancer|Advanced Breast Cancer|HER2/Neu-positive Breast Cancer
Interventions: DRUG: Capecitabine|DRUG: Lapatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preventing Early Childhood Obesity, Part 2: Family Spirit Nurture, Prenatal - 18 Months
Status: COMPLETED
Conditions: Obesity|Infant Obesity|Mother-Child Relations|Dietary Habits|Breast Feeding|Physical Activity|Childhood Obesity|Feeding Behavior
Interventions: BEHAVIORAL: Family Spirit Nurture (FSN)|OTHER: Injury Prevention Education (IPE)|OTHER: Optimized Standard Care (OSC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Safety and Efficacy of Multiple Doses of LT3001 Drug Product in AIS Subjects
Status: UNKNOWN
Conditions: Acute Ischemic Stroke
Interventions: DRUG: LT3001 Drug Product|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Efficacy and Safety Study of Elagolix (NBI-56418) in Women With Endometriosis
Status: COMPLETED
Conditions: Endometriosis, Pain
Interventions: DRUG: Elagolix|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Different Focus of Attention Instructions on Resistance Training and Its Transfer to Gait Parameters in Older Adults
Status: RECRUITING
Conditions: Healthy Aging|Healthy
Interventions: OTHER: Strength training with an internal focus of attention|OTHER: Strength training with a proprioceptive external focus of attention|OTHER: Strength training with a visual external focus of attention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: OXEL: Immune Checkpoint or Capecitabine or Combination Therapy as Adjuvant Therapy for TNBC With Residual Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Triple Negative Breast Cancer
Interventions: DRUG: Nivolumab|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anti-inflammatory Effects of Caffeine in Chronic Obstructive Pulmonary Disease (COPD) Subjects
Status: WITHDRAWN
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DIETARY_SUPPLEMENT: Caffeine|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Comparison of Ultrasound-guided Steroid Injection With Wrist Splint in Carpal Tunnel Syndrome
Status: UNKNOWN
Conditions: Carpal Tunnel Syndrome
Interventions: DRUG: Methylprednisolone Injection [Solu-Medrol]|DEVICE: wrist splint
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Autologous Immune Cell Therapy in Combination With LHRH-a in Patients With mCRPC
Status: UNKNOWN
Conditions: Metastatic Castration-resistant Prostate Cancer
Interventions: BIOLOGICAL: autologous immune cell therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Aripiprazole in Patients With Acute Bipolar Mania
Status: COMPLETED
Conditions: Bipolar Disorder
Interventions: DRUG: Placebo|DRUG: Aripiprazole|DRUG: Haloperidol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Cariprazine in Patients With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Cariprazine|DRUG: Aripiprazole|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT