pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Maximizing Yield of the Fecal Immunochemical Test for Colorectal Cancer Screening
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: BEHAVIORAL: 1 FIT kit|BEHAVIORAL: 2 FIT kit
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Safe Prescription of Opioids in Primary Care
Status: ACTIVE_NOT_RECRUITING
Conditions: Opioid-Related Disorders|Narcotic-Related Disorders|Addiction
Interventions: BEHAVIORAL: Educational intervention and prescription feedback|BEHAVIORAL: General information on treatment guidelines
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study of the Efficacy and Safety of Enlicitide Decanoate (MK-0616 Oral PCSK9 Inhibitor) in Adults With Hypercholesterolemia (MK-0616-008)
Status: COMPLETED
Conditions: Hypercholesterolemia|Familial Hypercholesterolemia
Interventions: DRUG: Enlicitide Decanoate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of High Absorption Pad in Split-thickness Skin Graft Donor Site Wound
Status: UNKNOWN
Conditions: Disorder of Skin Donor Site
Interventions: DEVICE: high absorption pad for blood and pus|DEVICE: commercial wound dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study of Imprime PGG® in Combination With Cetuximab in Subjects With Recurrent or Progressive KRAS Wild Type Colorectal Cancer
Status: TERMINATED
Conditions: Colorectal Cancer
Interventions: BIOLOGICAL: Imprime PGG + cetuximab|DRUG: Cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RANGER™ Paclitaxel Coated Balloon vs Standard Balloon Angioplasty
Status: COMPLETED
Conditions: Peripheral Artery Disease|Atherosclerosis|Artery Diseases, Peripheral|Plaque, Atherosclerotic|Occlusive Arterial Disease
Interventions: DEVICE: RANGER™ Paclitaxel Coated Balloon|DRUG: Paclitaxel|PROCEDURE: Standard Balloon Angioplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Diarrhea Predominant Irritable Bowel Syndrome in Females
Status: COMPLETED
Conditions: Irritable Bowel Syndrome
Interventions: DRUG: crofelemer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Omic Technologies Applied to the Study of B-cell Lymphoma for the Discovery of Diagnostic and Prognosis Biomarkers
Status: NOT_YET_RECRUITING
Conditions: Lymphoma, B-Cell|Neoplasms|Cancer|High-grade B-cell Lymphoma|Diffuse Large B Cell Lymphoma|Non Hodgkin Lymphoma|Metabolomics
Interventions: DIAGNOSTIC_TEST: Plasma metabolomic profile by Ultra-high performance liquid chromatography with quadrupole time-of-flight mass spectrometry (UPLC-QTOFMS)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Digital Therapeutics Research on Efficiency About Mild Cognitive Impairment Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Mild Cognitive Impairment
Interventions: DEVICE: ET-101|DEVICE: Sham Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Atrosimab (ATM001) in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: BIOLOGICAL: ATM001|BIOLOGICAL: ATM001 Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of SST 0225, a Topical Ibuprofen Cream, in the Treatment of Pain Associated With Acute Ankle Sprain
Status: COMPLETED
Conditions: Acute Ankle Sprain
Interventions: DRUG: Placebo|DRUG: SST-0225 Topical Ibuprofen Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility of IV Tc-99m-tilmanocept for Imaging of M2-like TAMs in Metastatic Melanoma
Status: TERMINATED
Conditions: Melanoma
Interventions: DRUG: Tc-99m tilmanocept
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Piloting the Attention Training Technique for Post-Stroke Emotionalism
Status: NOT_YET_RECRUITING
Conditions: Stroke|Emotionality|Pseudobulbar Affect|Lability Emotional|Crying
Interventions: BEHAVIORAL: Attention Training Technique
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mechanisms of Palmitoylethanolamide (PEA) to Alter Pain Sensitivity in Knee Osteoarthritis
Status: ACTIVE_NOT_RECRUITING
Conditions: Osteoarthritis, Knee
Interventions: DIETARY_SUPPLEMENT: palmitoylethanolamide|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: BMAC Loaded Collagen Jumping the Gap Around Immediate Implants
Status: RECRUITING
Conditions: Implant Site Reaction|Dental Implantation
Interventions: DRUG: BMAC/ collagen|PROCEDURE: Autograft harvesting from chin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Learn How Gadoquatrane Moves Into, Through, and Out of the Body and How Safe it is in Children (From Birth to <18 Years), Who Will Undergo a Contrast Enhanced MRI (Quanti Pediatric)
Status: RECRUITING
Conditions: Contrast Enhancement in Magnetic Resonance Imaging|Children
Interventions: DRUG: Gadoquatrane (BAY1747846)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Doxorubicin and Bortezomib in Treating Patients With Liver Cancer
Status: COMPLETED
Conditions: Adult Primary Hepatocellular Carcinoma|Advanced Adult Primary Liver Cancer|Localized Unresectable Adult Primary Liver Cancer|Recurrent Adult Primary Liver Cancer
Interventions: DRUG: doxorubicin|DRUG: bortezomib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Metronomic Oral Vinorelbine Plus Anlotinib in HER2-negative Metastatic Breast Cancer Patients
Status: RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: metronomic oral vinorelbine plus anlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transcranial Direct Current Stimulation (tDCS) as Therapeutical Strategy for Negative Symptoms in Schizophrenia
Status: WITHDRAWN
Conditions: Transcranial Direct Current Stimulation|Schizophrenia
Interventions: PROCEDURE: Transcranial Direct Current Stimulation (tDCS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Deutetrabenazine to Control Symptoms of Dysphagia Associated With HD
Status: UNKNOWN
Conditions: Huntington Disease
Interventions: DRUG: Deutetrabenazine Oral Tablet [Austedo]|DRUG: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Electroacupuncture vs Sham Electrocupuncture for Mixed Urinary Incontinence
Status: NOT_YET_RECRUITING
Conditions: Mixed Urinary Incontinence
Interventions: OTHER: Electroacupuncture|OTHER: Sham electroacupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Aerobic Training and Inspiratory Muscle Training in Patients During Hematopoietic Stem Cell Transplantation
Status: UNKNOWN
Conditions: Lymphoma|Myeloma|Leukemia|Aplastic Anemia
Interventions: OTHER: Inspiratory Muscle Training|OTHER: Aerobic Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the MEL 80 Excimer Laser Using LASIK in the Treatment of Mixed Astigmatism
Status: COMPLETED
Conditions: Mixed Astigmatism
Interventions: DEVICE: MEL 80 Mixed Astigmatism Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Three Side Hole Infusion Catheter on CT Image Quality Compared to a Standard Infusion Catheter
Status: COMPLETED
Conditions: Contrast Enhanced Computed Tomography (CT) Scanning
Interventions: DEVICE: Becton Dickinson Nexiva Diffusics System|DEVICE: Standard intravenous catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Behavioral Economics and Self-Determination Theory to Change Diabetes Risk (BEST Change)
Status: COMPLETED
Conditions: Pre Diabetes
Interventions: BEHAVIORAL: Automated educational text messages|BEHAVIORAL: Autonomy-supportive automated educational text messages|BEHAVIORAL: Financial incentives|BEHAVIORAL: Tailored text messages
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Trial of INI-4001 in Patients With Advanced Solid Tumours
Status: NOT_YET_RECRUITING
Conditions: Advanced Solid Tumor
Interventions: DRUG: INI-4001|COMBINATION_PRODUCT: Nivolumab|COMBINATION_PRODUCT: Pembrolizumab|COMBINATION_PRODUCT: Cemiplimab|COMBINATION_PRODUCT: Avelumab|COMBINATION_PRODUCT: Atezolizumab|COMBINATION_PRODUCT: Durvalumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single Dose Ultibro Breezhaler by Sd-DPI Versus Ipratropium/Salbutamol by Nebulizer in COPD
Status: COMPLETED
Conditions: COPD
Interventions: DRUG: indacaterol/glycopyrronium 110/50 Breezhaler®|DEVICE: Placebo by Breezhaler®|DRUG: ipratropium/salbutamol 0,5 mg, 2,5 mg by nebulisation|DEVICE: Placebo by nebulisation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Dietary Nitrate Supplementation on Cardiorespiratory Control in Chronic Heart Failure
Status: COMPLETED
Conditions: Heart Failure, Systolic
Interventions: DIETARY_SUPPLEMENT: Nitrate supplementation|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Early Response to Interferon Combined Short-Term Nucleoside Analogue Therapy in HBeAg(+) Chronic Hepatitis B
Status: UNKNOWN
Conditions: Hepatitis B, Chronic
Interventions: DRUG: interferon α plus nucleoside analogue|DRUG: interferon α|DRUG: interferon α
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: QVA vs. Salmeterol/Fluticasone, 52-week Exacerbation Study, FLAME (EFfect of Indacaterol Glycopyronium Vs Fluticasone Salmeterol on COPD Exacerbations)
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: DRUG: QVA149|DRUG: Long acting B2 agonist (LABA) and inhaled corticosteroid (ICS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Inpatient Closed Loop Glucose Control With the Gen 2 GlucoSTAT
Status: WITHDRAWN
Conditions: Type 1 Diabetes|Type 2 Diabetes Treated With Insulin
Interventions: DEVICE: GlucoSTAT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Single-bundle Versus Double-bundle Anterior Cruciate Ligament Reconstruction
Status: ACTIVE_NOT_RECRUITING
Conditions: Anterior Cruciate Ligament Reconstruction
Interventions: PROCEDURE: ACL reconstruction single bundle|PROCEDURE: ACL reconstruction double bundle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: An Efficacy and Safety Study of Oral Osmotic Therapeutic System (OROS) Hydromorphone Hydrochloride (HCl) in Participants With Cancer Related Pain
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Hydromorphone HCl|DRUG: Oxycodone HCl CR|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Reproductive Health Survivorship Care Plan
Status: COMPLETED
Conditions: Breast Cancer|Hot Flashes|Sexual Dysfunction|Fertility|Contraception
Interventions: OTHER: Reproductive Health Survivorship Care Plan (SCPR)|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Arrhythmias in Post-Myocardial Infarction Patients
Status: COMPLETED
Conditions: Myocardial Infarction|Coronary Artery Disease|Arrythmia|ECG Electrical Alternans|Atrioventricular Block|Atrial Fibrillation|Atrial Flutter|Ventricular Tachycardia|Ventricular Fibrillation|Ventricular Arrythmia
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of a Short Uncemented Femoral Stem to a Similar Standard Uncemented Femoral Stem
Status: RECRUITING
Conditions: Osteoarthritis, Hip
Interventions: DEVICE: total hip replacement - standard femoral stem|DEVICE: total hip replacement - short femoral stem
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluating Acceptance of New Liquid Somatropin Formulation in Children With Growth Hormone Deficiency
Status: COMPLETED
Conditions: Growth Hormone Disorder|Growth Hormone Deficiency in Children|Genetic Disorder|Turner Syndrome
Interventions: DRUG: somatropin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase Ⅰ Trial to Evaluate the Safety and Immunogenicity of SARS-CoV-2 Vaccine LYB001
Status: UNKNOWN
Conditions: COVID-19
Interventions: BIOLOGICAL: LYB001|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety/Pharmacokinetic Study Comparing Intracisternal EG-1962 to Standard of Care Enteral Nimodipine in Adults With aSAH
Status: TERMINATED
Conditions: Subarachnoid Hemorrhage, Aneurysmal
Interventions: DRUG: EG-1962 (nimodipine microparticles)|DRUG: Enteral Nimodipine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RELATIONSHIP BETWEEN INITIAL PROBING DEPTH AND CHANGES IN CLINICAL PARAMETERS FOLLOWING NON-SURGICAL PERIODONTAL TREATMENT IN CHRONIC PERIODONTITIS PATIENTS
Status: COMPLETED
Conditions: Chronic Periodontitis
Interventions: DEVICE: Gracey Curettes
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized Trial Assessing the Roles of AraC in Newly Diagnosed APL Promyelocytic Leukemia (APL)
Status: COMPLETED
Conditions: Leukemia, Promyelocytic, Acute
Interventions: DRUG: Arac
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Dog Adoption in Veterans With Posttraumatic Stress Disorder (PTSD)
Status: COMPLETED
Conditions: Posttraumatic Stress Disorder (PTSD)
Interventions: OTHER: Shelter Dog Adoption
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Concomitant Chemo-radiotherapy Plus VIDL Chemotherapy in NK/T-cell Lymphoma
Status: COMPLETED
Conditions: NK/T-cell Lymphoma of Nasal Cavity
Interventions: OTHER: CCRT followed by VIDL chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Diagnostic Performance of [18F]CTT1057 for PSMA-positive Tumors Detection
Status: COMPLETED
Conditions: Prostatic Neoplasms|Prostate Cancer
Interventions: DRUG: [18F]CTT1057
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Gemcitabine Hydrochloride With or Without Bevacizumab in Treating Patients Who Are Undergoing Surgery for Pancreatic Cancer
Status: WITHDRAWN
Conditions: Adenocarcinoma of the Pancreas|Recurrent Pancreatic Cancer|Stage I Pancreatic Cancer|Stage II Pancreatic Cancer|Stage III Pancreatic Cancer
Interventions: DRUG: bevacizumab|DRUG: gemcitabine hydrochloride|PROCEDURE: adjuvant therapy|PROCEDURE: anti-cytokine therapy|PROCEDURE: antiangiogenesis therapy|PROCEDURE: antibody therapy|PROCEDURE: biological therapy|PROCEDURE: chemotherapy|PROCEDURE: conventional surgery|PROCEDURE: growth factor antagonist therapy|PROCEDURE: monoclonal antibody therapy|PROCEDURE: surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Reducing Atrial Pacing Rate to Reduce Atrial Fibrillation in Patients With Sick Sinus Syndrome.
Status: COMPLETED
Conditions: Sinus Node Disease|Atrial Fibrillation
Interventions: DEVICE: DDDR-60|DEVICE: DDD-40
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GS-5885, GS-9451, Tegobuvir and Ribovirin in Treatment-Experienced Subjects With Chronic Genotype 1a Or 1b Hepatitis C Virus (HCV) Infection
Status: COMPLETED
Conditions: Hepatitis C, Chronic
Interventions: DRUG: GS-5885|DRUG: GS-9451|DRUG: tegobuvir|DRUG: placebo to match tegobuvir|DRUG: placebo to match RBV|DRUG: Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Platelet Rich Plasma for Uterine Scar
Status: NOT_YET_RECRUITING
Conditions: Cesarean Section Complications|Uterine Bleeding|Pelvic Pain|Menstrual Irregularity
Interventions: OTHER: Platelet Rich Plasma
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Lactoferrin and Lysozyme Supplementation for Environmental Enteric Dysfunction
Status: COMPLETED
Conditions: Environmental Enteric Dysfunction
Interventions: DIETARY_SUPPLEMENT: Lactoferrin|DIETARY_SUPPLEMENT: Lysozyme|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Role of Highly Selective Androgen Receptor (AR) Targeted Therapy in Men With Biochemically Relapsed Hormone Sensitive Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: ARN-509|DRUG: LHRH Agonist
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Clinical Efficacy of 2 Paravertebral Block Strategies in Thoracic Surgery by Thoracotomy: by the Anesthetist (Paravertebral Block Guided by Ultrasound) and by the Thoracic Surgeon (Paravertebral Block Visual)
Status: UNKNOWN
Conditions: Pain
Interventions: OTHER: paravertebral block by the anesthetist before incision (paravertebral block guided by ultrasound)|OTHER: paravertebral block by the thoracic surgeon at chest closure (paravertebral block visual).
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare the Efficacy and Safety of Oral Azacitidine Plus Best Supportive Care Versus Best Supportive Care as Maintenance Therapy in Japanese Participants With Acute Myeloid Leukemia (AML) in Complete Remission
Status: RECRUITING
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Oral Azacitidine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Canadian Glaucoma Study
Status: TERMINATED
Conditions: Glaucoma
Interventions: DRUG: Intraocular pressure reduction|PROCEDURE: Argon laser trabeculoplasty|PROCEDURE: Trabeculectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Using Smart Phone Technology to Support HIV Medication Refill Adherence in Virginia
Status: UNKNOWN
Conditions: Hiv|Adherence, Medication
Interventions: OTHER: PositiveLinks RX Mobile App|OTHER: PositiveLinks RX Portal
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Double-blind, Placebo Controlled Trial of Risperidone for the Treatment of Anorexia Nervosa
Status: COMPLETED
Conditions: Anorexia Nervosa
Interventions: DRUG: Risperidone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Occupational Therapy's Role in Promoting Community Wellness Utilizing Sit-Stand Workstations
Status: COMPLETED
Conditions: Musculoskeletal Pain|Musculoskeletal Strain|Sedentary Lifestyle
Interventions: DEVICE: Ergotron WorkFit - TL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Determinants of Lower Limb Muscle Atrophy Induced During an Hospitalization for Exacerbation of COPD
Status: TERMINATED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)|Exacerbation Copd|Muscle Atrophy
Interventions: OTHER: Comparison of clinical and biological characteristics of patients
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Ventilatory Management of the Preterm Neonate in the Delivery Room
Status: COMPLETED
Conditions: Respiratory Distress Syndrome, Newborn
Interventions: PROCEDURE: Resuscitation of preterm neonates by sustained lung inflation through T piece device followed by CPAP|PROCEDURE: Resuscitation of preterm neonates by intermittent bag and mask ventilation using self inflating bag.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Prevention of Post-Cardiac Surgery Acute Kidney Injury by Proton Pump Inhibitor
Status: RECRUITING
Conditions: Acute Kidney Injury
Interventions: DRUG: Pantoprazole|DRUG: Famotidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Effects of a Complete Diet in Critically Ill Patients With Stress Hyperglycemia
Status: COMPLETED
Conditions: Critical Illness|Hyperglycemia|Dietary Modification|Metabolic Stress Hyperglycemia|Mechanical Ventilation Complication
Interventions: DIETARY_SUPPLEMENT: T-Diet plus Diabet IR|DIETARY_SUPPLEMENT: ISOSOURCE PROTEIN FIBRE|DIETARY_SUPPLEMENT: GLUCERNA SELECT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Multiple Dose Study to Evaluate Subcutaneous AMG 108 in Subjects With Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: AMG 108|DRUG: AMG 108|DRUG: AMG 108|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Safety and Pharmacology of GDC-0980 in Combination With Paclitaxel With or Without Bevacizumab in Patients With Locally Recurrent or Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: GDC-0980|DRUG: bevacizumab|DRUG: paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hyper-synchronicity in Hypertrophic Cardiomyopathy (HCM) : Description, Mechanism and Origin With a Multi-imaging Approach to Predict Dual Chamber Pacing Response
Status: COMPLETED
Conditions: Hypertrophic Cardiomyopathy|Mechanical Hyper-synchronicity
Interventions: PROCEDURE: Echocardiography (TEE)|DEVICE: Magnetic resonance imaging (MRI) with gadolinium enhancement|DEVICE: Magnetic resonance imaging (MRI) without gadolinium enhancement|PROCEDURE: 3D electrocardiographic mapping (ECM)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pharmacological Inhibition of Lactation After 16 to 20 Week Abortion
Status: RECRUITING
Conditions: Lactation Suppressed|Second Trimester Abortion
Interventions: DRUG: Cabergoline|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness Study of Mirtazapine Combined With Paroxetine in Major Depressive Patients Without Early Improvement
Status: COMPLETED
Conditions: Major Depression
Interventions: DRUG: mirtazapine|DRUG: paroxetine 20mg QD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Inorganic Nitrite to Amplify the Benefits and Tolerability of Exercise Training in Heart Failure With Preserved Ejection Fraction (HFpEF) (INABLE-Training)
Status: COMPLETED
Conditions: Heart Failure
Interventions: DRUG: Placebo|DRUG: Sodium Nitrite|DEVICE: Accelerometer|OTHER: Cardiac Exercise Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Multihole Fully Covered Metallic Stents in the Management of Malignant Biliary Obstruction
Status: COMPLETED
Conditions: Malignant Biliary Obstruction
Interventions: DEVICE: group 1|DEVICE: group 2|DEVICE: group 3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of HIP1601 Capsule
Status: COMPLETED
Conditions: Erosive Gastroesophageal Reflux Disease
Interventions: DRUG: HIP1601|DRUG: HGP1705|DRUG: HIP1601 Placebo|DRUG: HGP1705 Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Topical and Intravenous Tranexamic Acid (TXA) on Thrombogenic Markers in Patients Undergoing Knee Replacement
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: DRUG: Intravenous tranexamic acid|DRUG: Topical tranexamic acid|DRUG: Intravenous saline|DRUG: Topical saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Possible Safety and Efficacy of Dapagliflozin in the Prophylaxis of Doxorubicin-Induced Cardiotoxicity
Status: NOT_YET_RECRUITING
Conditions: Doxorubicin Induced Cardiomyopathy|Breast Cancer
Interventions: DRUG: Dapagliflozin 10mg Tab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Chronic Administration of Diosmectite (SMECTA®) in Subjects With Chronic Diarrhoea
Status: COMPLETED
Conditions: Chronic Functional Diarrhea of Unknown Origin
Interventions: DRUG: Diosmectite (Smecta®)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study Evaluating the Safety and Intraocular Pressure (IOP) Lowering Response of Brimonidine Tartrate Ophthalmic Solution in Subjects With Open Angle Glaucoma or Ocular Hypertension
Status: COMPLETED
Conditions: Glaucoma and Ocular Hypertension
Interventions: DRUG: Brimonidine Tartrate 0.025%|DRUG: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Healthy Communities: A Healthy City Preventive Program on Cardiovascular Health and Well-being (HC)
Status: ENROLLING_BY_INVITATION
Conditions: Heart Disease Risk Factors|Healthy Lifestyle|Health Behavior
Interventions: BEHAVIORAL: the SI! Program for Secondary Schools (NCT03504059)|BEHAVIORAL: the Fifty-Fifty Program (NCT02367963)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: MT2017-45: CAR-T Cell Therapy for Heme Malignancies
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Lymphoblastic Leukemia|Large B-cell Lymphoma
Interventions: DRUG: KYMRIAH|DRUG: YESCARTA|DRUG: Fludarabine 30mg/m2 4 doses|DRUG: Cyclophosphamide 500 mg/m2; 2 doses|DRUG: Fludarabine 30mg/m2 3 doses|DRUG: Cyclophosphamide 500 mg/m2; 3 doses|DRUG: Fludarabine 25mg/m2 3 days|DRUG: Cyclophosphamide 250 mg/m2; 3 days|DRUG: Tecartus|DRUG: Abecma, Intravenous Suspension|DRUG: Cyclophosphamide 900 mg/m2; 1 day|DRUG: Breyanzi Injectable Product
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effects of rTMS in Rehabilitation Following Spinal Cord Injury
Status: COMPLETED
Conditions: Spinal Cord Injury|Rehabilitation|Transcranial Magnetic Stimulation|Neurorehabilitation
Interventions: DEVICE: repetitive transcranial magnetic stimulation|OTHER: Sham stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Relationship Between Spinopelvic Parameters and Clinical Symptoms of Low-grade Lumbar Isthmic Spondylolisthesis
Status: COMPLETED
Conditions: Isthmic Spondylolisthesis
Interventions: RADIATION: PI-LL
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Oropharyngeoesophageal Topical Anesthesia Versus Propofol - Ketamine Sedation for Upper Gastrointestinal Endoscopy
Status: COMPLETED
Conditions: Upper Gastrointestinal Endoscopy|Topical Anesthesia|Intravenous Sedation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use of a Non-medicated Plaster in Chronic Lumbar Back Pain.
Status: COMPLETED
Conditions: Back Pain
Interventions: DEVICE: The FIT Therapy patch (D. FENSTEC s.r.l. Altavilla Vicentina, Italy) is a medical device class 1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neurorehabilitation Through Hippotherapy of a Brain Stroke
Status: RECRUITING
Conditions: Cerebrovascular Accident|Neurorehabilitation|Neuroplasticity|Hippotherapy|Silent Neurofunctional Barriers|Functional Deficit|Cognitive Deficit|Psychological Trauma|Autonomy|Quality of Life|Caregiver Burnout
Interventions: OTHER: Hippotherapy|OTHER: Conventional Neurorehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: HARMONY Study (Hypertension Analysis of Stress Reduction Using Mindfulness Meditation and Yoga)
Status: COMPLETED
Conditions: Hypertension
Interventions: BEHAVIORAL: Mindfulness Based Stress Reduction (MBSR) Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: CPX-351 in Treating Patients With Newly Diagnosed, High-Risk Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Acute Myeloid Leukemia|Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome|Secondary Acute Myeloid Leukemia
Interventions: OTHER: Laboratory Biomarker Analysis|DRUG: Liposome-encapsulated Daunorubicin-Cytarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Resilience Against Depression Disparities (Also Known as Resilience Education to Reduce Depression Disparities)
Status: UNKNOWN
Conditions: Depressive Symptoms
Interventions: BEHAVIORAL: Resiliency Class|OTHER: Resource for Services (RS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Osteopatic Cranial Techniques on the Audiometric and Tympanometric Values in Children Suffering From Otitis Media With Effusion.
Status: WITHDRAWN
Conditions: Otitis Media With Effusion
Interventions: PROCEDURE: treated with osteopatic cranial techniques|PROCEDURE: Treatment with placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Telehealth Cognitive Behavioral Stress Management for Adults With Cystic Fibrosis
Status: COMPLETED
Conditions: Anxiety|Depression|Stress|Coping Skills|Cystic Fibrosis
Interventions: BEHAVIORAL: Cognitive Behavioral Stress Management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effectiveness of Kaltenborn Mobilizations Versus Muscle Energy Technique in Adhesive Capsulitis.
Status: UNKNOWN
Conditions: Adhesive Capsulitis of Shoulder
Interventions: OTHER: Muscle energy technique|OTHER: Kaltonborn mobilizations
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Psychological Therapy for Dissociation, Trauma and Voices: A Single Case Experimental Design
Status: COMPLETED
Conditions: Dissociation|Auditory Hallucination|Trauma, Psychological|Psychosis
Interventions: OTHER: Connection to Environment with Cognitive Therapy (CONNECT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Safety, Tolerability, and Pharmacokinetics of Cefiderocol in Hospitalized Neonates and Infants
Status: RECRUITING
Conditions: Gram-Negative Bacterial Infections
Interventions: DRUG: Cefiderocol|DRUG: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Efficacy and Safety of MEDI2070 in Patients With Active, Moderate-to-severe Crohn's Disease.
Status: COMPLETED
Conditions: Crohn's Disease
Interventions: DRUG: MEDI2070|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Non-pharmacological Treatment for Essential Isolated Systolic Hypertension in Elderly
Status: COMPLETED
Conditions: Systolic Essential Hypertension
Interventions: OTHER: Loaded breathing training|OTHER: Unloaded breathing training|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Empirical vs 2nd Line Antibiotic Therapy in Health-care Associated Infections in Cirrhosis
Status: UNKNOWN
Conditions: Cirrhosis
Interventions: DRUG: Imipenem|DRUG: Vancomycin|DRUG: azithromycin|DRUG: Cefotaxime|DRUG: Amoxicillin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Short-term Atorvastatin Treatment on Vaccination Efficacy in Nonresponder Persons to Hepatitis B Vaccine
Status: UNKNOWN
Conditions: Hepatitis B|Vaccination Failure
Interventions: DRUG: Atorvastatin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy of a Metallic Cannula Versus A Standard Needle for Soft Tissue Augmentation of the Nasolabial Folds
Status: COMPLETED
Conditions: Wrinkles
Interventions: PROCEDURE: hyaluronic acid with metallic cannula or standard needle.|DRUG: Hyaluronic acid injected with the new tool.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of PHGG-rich Enteral Nutrition to on the Infection in Liver Transplant Recipients: A Prospective, Double-blind, Randomized Controlled Study
Status: NOT_YET_RECRUITING
Conditions: Infections
Interventions: DRUG: PHGG-rich enteral nutrtiion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Familial and Functional Study of Genetic Variants Identified in People With Schizophrenia, Bipolar Disorder, Autism Spectrum Disorder or Resistant Depression
Status: RECRUITING
Conditions: Psychiatric Disorder
Interventions: GENETIC: study of the transmission of genetic variants
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Local Anesthetic Treatment of Oral Pain in Patients With Mucositis
Status: COMPLETED
Conditions: Mucositis
Interventions: DRUG: Bupivacaine|DRUG: Standard treatment (lidocaine viscous solution, morphine, paracetamol, NSAID, gabapentin)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Endocrine and Emotional Effects of Lisdexamfetamine and d-Amphetamine.
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Lisdexamfetamine, d-amphetamine, Placebo|DRUG: d-amphetamine, Placebo, Lisdexamfetamine|DRUG: Placebo, Lisdexamfetamine, d-amphetamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Investigation of The Effect of "Instrument-Assisted Soft Tissue Mobilization" in Individuals With Lumbar Disc Herniation
Status: COMPLETED
Conditions: Instrument-assisted Soft Tissue Mobilization|Treatment|Exercise|Pain
Interventions: OTHER: Observational|OTHER: IASTM Technique Application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Imatinib Mesylate and 17-N-Allylamino-17-Demethoxygeldanamycin in Treating Patients With Chronic Myelogenous Leukemia
Status: COMPLETED
Conditions: Leukemia
Interventions: DRUG: imatinib mesylate|DRUG: tanespimycin
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of a 2-dose Ebola Vaccine Regimen of Ad26.ZEBOV Followed by MVA-BN-Filo in Healthy Pregnant Women
Status: COMPLETED
Conditions: Healthy
Interventions: BIOLOGICAL: Ad26.ZEBOV|BIOLOGICAL: MVA-BN-Filo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy Trial of a Dapivirine Vaginal Matrix Ring in Healthy HIV-Negative Women
Status: COMPLETED
Conditions: HIV Infections
Interventions: COMBINATION_PRODUCT: Placebo Vaginal Ring|COMBINATION_PRODUCT: Dapivirine Vaginal Ring, 25 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Investigation of the Efficacy of Non-Invasive Vagus Nerve Stimulation and Physiotherapy in Unilateral Vestibular Hypofunction Patients
Status: RECRUITING
Conditions: Vestibular Diseases|Vestibular Vertigo|Vertigo
Interventions: DEVICE: non-invasive vagus nerve stimulation|BEHAVIORAL: vestibular rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ESP vs QL for Total Abdominal Hysterectomy
Status: TERMINATED
Conditions: Postoperative Pain
Interventions: PROCEDURE: Erector Spinae Plane block|PROCEDURE: Quadratus Lumborum Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: COPE Intervention for Parents of Children With Epilepsy
Status: COMPLETED
Conditions: Epilepsy
Interventions: BEHAVIORAL: COPE (Creating Opportunities for Parent Empowerment)|BEHAVIORAL: Standard education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Omega-3 Fatty Acids Supplementation Improves Early-stage Diabetic Nephropathy and Subclinical Atherosclerosis in Pediatric Patients With Type 1 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: DRUG: oral omega-3 fatty acids supplementation|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Deep Brain Stimulation of the Cuneiform Nucleus for Levodopa-resistant Freezing of Gait in Parkinson's Disease
Status: RECRUITING
Conditions: Parkinson Disease
Interventions: DEVICE: Vercise DBS System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single Nucleotide Polymorphism (SNP) in Schizophrenia and Schizophrenia Spectrum Disorders: a Population Association Analysis With Hong Kong Chinese
Status: COMPLETED
Conditions: Schizophrenia
Interventions: PROCEDURE: Extraction of 10ml blood sample for extraction of genomic DNA using DNA purification kits
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Nitazoxanide Pharmacokinetic Parameters in Hepatic Impaired Patients
Status: COMPLETED
Conditions: Moderate Hepatic Impairment|Severe Hepatic Impairment|Liver Diseases
Interventions: DRUG: Nitazoxanide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Carfilzomib, Lenalidomide and Dexamethasone Versus Lenalidomide and Dexamethasone in High- Risk SMM
Status: ACTIVE_NOT_RECRUITING
Conditions: Smouldering Myeloma
Interventions: DRUG: Carfilzomib|DRUG: Dexamethasone|DRUG: Lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Enhancing Children's Cognitive and Brain Health Through Physical Activity Training (FITKids2)
Status: COMPLETED
Conditions: Cognitive Ability, General|Achievement
Interventions: BEHAVIORAL: Physical Activity|BEHAVIORAL: Physical Activity
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Human Umbilical Cord Mesenchymal Stem Cell Transplantation in Articular Cartilage Defect
Status: COMPLETED
Conditions: Cartilage Diseases|Osteoarthritis
Interventions: BIOLOGICAL: Human umbilical cord mesenchymal stem cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Heart Health 4 Moms Trial to Reduce CVD Risk After Preeclampsia
Status: COMPLETED
Conditions: Cardiovascular Disease|Preeclampsia|Hypertension|Post-partum Weight Retention
Interventions: BEHAVIORAL: Web-based educational and motivational modules|BEHAVIORAL: Information and Screening Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Linear Ablation Versus Focal Ablation of Complex Fractionated Atrial Electrograms in Persistent Atrial Fibrillation
Status: WITHDRAWN
Conditions: Persistent Atrial Fibrillation
Interventions: PROCEDURE: radiofrequency catheter ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Perturbations Exercises in Improving Balance, Function and Mobility in Stroke Patients
Status: COMPLETED
Conditions: Stroke
Interventions: OTHER: Perturbation|OTHER: Conventional Physiotherapy Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT