pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Cotrimoxazole Versus Amoxicillin in the Treatment of Community Acquired Pneumonia in Children Aged 2-59 Months
Status: COMPLETED
Conditions: Childhood Pneumonia
Interventions: DRUG: Amoxicillin|DRUG: Cotrimoxazole|DRUG: Amoxicillin placebo|DRUG: Cotrimoxazole placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Combined Ephedrine and Lidocaine Pretreatment on Pain and Hemodynamic Changes Due to Propofol Injection
Status: COMPLETED
Conditions: Pain Due to Propofol Injection|Hemodynamic Changes Due to Propofol Injection
Interventions: DRUG: Ephedrine 30microgram/kg|DRUG: lidocaine0.5mg/kg -ephedrine30 micrograms/kg|DRUG: ephedrine 70 microgram/kg|DRUG: lidocaine 0.5mg/kg|DRUG: normal saline 2ml
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Esomeprazole for Non-Allergic Rhinitis: A Double-blind, Placebo Controlled Trial
Status: COMPLETED
Conditions: Vasomotor Rhinitis
Interventions: DRUG: esomeprazole|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ipilimumab With Carboplatin and Paclitaxel in Patients With Unresectable Stage III and Stage IV Melanoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Untreated Stage III Melanoma or Stage IV Melanoma
Interventions: BIOLOGICAL: Ipilimumab|DRUG: Carboplatin|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Latanoprost , Travoprost and Tafluprost in Reducing IOP Fluctuation in POAG Patients
Status: COMPLETED
Conditions: Primary Open Angle Glaucoma
Interventions: DRUG: Latanoprost 0.005% Ophthalmic Solution|DRUG: Travoprost 0.004% ophthalmic solution|DRUG: Tafluprost Ophthalmic 0.0015% Ophthalmic Solution
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Prophylaxis, ACtivity and Effectiveness (SPACE) in Hemophilia Patients Currently Treated With ADVATE or RIXUBIS
Status: COMPLETED
Conditions: Hemophilia A|Hemophilia B
Interventions: BIOLOGICAL: ADVATE (Antihemophilic Factor [Recombinant])|BIOLOGICAL: RIXUBIS (Coagulation Factor IX [Recombinant])
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Action Observation and Motor Imagery Induced Hypoalgesia in Asymptomatic Subjects
Status: COMPLETED
Conditions: Analgesia|Exercise
Interventions: BEHAVIORAL: Action Observation plus motor imagery|BEHAVIORAL: Motor imagery|BEHAVIORAL: Exercise plus action Observation and motor imagery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating the Success Rate of Outpatient Management of the Total Benign Hysterectomy by Transvaginal Natural Orifice Transluminal Endoscopic Surgery (vNOTES) Compared to Each of the Two Laparoscopic Routes (Conventional and Robot-assisted).
Status: RECRUITING
Conditions: Surgery|Gynecologic Disease
Interventions: PROCEDURE: Benign Hysterectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of BCG Vaccination in the Prevention of COVID19 Via the Strengthening of Innate Immunity in Health Care Workers
Status: UNKNOWN
Conditions: Infection|Viral, Agent as Cause of Disease Classified Elsewhere
Interventions: BIOLOGICAL: BCG GROUP|OTHER: PLACEBO GROUP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Study to Investigate the Safety/Tolerability and Pharmacokinetics/Pharmacodynamics of CKD-519
Status: COMPLETED
Conditions: Dyslipidemia
Interventions: DRUG: CKD-519|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Purpose of This Study is to Evaluate the Safety and Efficacy of One, Two, or Three iStents for the Reduction of Intraocular Pressure in Open-angle Glaucoma Subjects
Status: COMPLETED
Conditions: Primary Open Angle Glaucoma (POAG)
Interventions: DEVICE: iStent|DEVICE: iStent|DEVICE: iStent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Gastric Emptying and Gallbladder Motility Study
Status: COMPLETED
Conditions: Gastric Emptying
Interventions: DIETARY_SUPPLEMENT: Plant sterol containing drink|DIETARY_SUPPLEMENT: Standard macaroni meal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Colonoscope Passive Bending Function
Status: COMPLETED
Conditions: Colitis|Adenoma|Carcinoma|Functional Colonic Disease
Interventions: DEVICE: Passive bending function|DEVICE: No passive bending function
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Fast Antibiotic Susceptibility Testing for Gram Negative Bacteremia Trial
Status: RECRUITING
Conditions: Gram-negative Bacteremia|Bloodstream Infection
Interventions: DIAGNOSTIC_TEST: Reveal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: DIAGNOSTIC
Clinical trial: An Open Label, Multi-center, Phase I Clinical Study to Evaluate the Safety, Effectiveness and Pharmacokinetic Characteristics of SIM1803-1A in Patients With Locally Advanced/Metastatic Solid Tumors With NTRK, ROS1 or ALK Gene Fusion Mutations.
Status: UNKNOWN
Conditions: Advanced or Metastatic Solid Tumors With NTRK, ROS1 or ALK Gene Fusion
Interventions: DRUG: SIM1803-1A
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial to Evaluate the Chronic Safety and Tolerance of Turmipure Gold™ in Healthy Subjects
Status: COMPLETED
Conditions: Gastrointestinal Tolerance|Liver Function|Kidney Function
Interventions: DIETARY_SUPPLEMENT: Turmipure Gold™|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety and Clinical Effectiveness of Pipeline™ Shield Devices for Intracranial Aneurysms
Status: UNKNOWN
Conditions: Intracranial Aneurysm|Cerebral Aneurysm|Subarachnoid Hemorrhage|Stroke, Acute|Cerebral Hemorrhage|Cerebral Stroke|Neurologic Disorder
Interventions: DEVICE: Pipeline™ Flex Embolization Device with Shield Technology™
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phase 2 Randomized Trial of Flexible Dosing Schedule of 177Lu-PSMA-617 for the Treatment of Metastatic Castration-Resistant Prostate Cancer (FLEX-MRT)
Status: RECRUITING
Conditions: Prostate Carcinoma|Stage IVB Prostate Cancer American Joint Committee on Cancer (AJCC) v8
Interventions: PROCEDURE: Computed Tomography|OTHER: Gallium Ga 68 Gozetotide|DRUG: Lutetium Lu 177 Vipivotide Tetraxetan|PROCEDURE: Positron Emission Tomography|PROCEDURE: PSMA PET Scan|OTHER: Questionnaire Administration|PROCEDURE: Single Photon Emission Computed Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SBRT and Atezolizumab in the Management of Recurrent, Persistent, or Metastatic Cervical Cancer
Status: RECRUITING
Conditions: Cervical Cancer|Cervical Cancer Recurrent|Cervical Cancer Metastatic
Interventions: RADIATION: Stereotactic body radiation therapy (SBRT)|DRUG: Atezolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Transcranial Magnetic Stimulation Therapy in Patients With Lumbar Radiculopathy
Status: UNKNOWN
Conditions: Lumbar Radiculopathy
Interventions: DEVICE: Repetitive transcranial magnetic stimulation (rTMS)|DRUG: Transforaminal epidural steroid injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of Art Therapy During Cognitive Processing Therapy for PTSD
Status: TERMINATED
Conditions: Post-traumatic Stress Disorder|Stress Disorder, Post-Traumatic
Interventions: BEHAVIORAL: Cognitive Processing therapy|BEHAVIORAL: Art + CPT|BEHAVIORAL: CPT + Art Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Neurophysiologic and Clinical Effects of Single Dose Drug Challenge
Status: RECRUITING
Conditions: Fragile X Syndrome
Interventions: DRUG: Baclofen|DRUG: Memantine|DRUG: Roflumilast|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: CAMPFIRE: A Study of Ramucirumab (LY3009806) in Children and Young Adults With Desmoplastic Small Round Cell Tumor
Status: ACTIVE_NOT_RECRUITING
Conditions: Desmoplastic Small Round Cell Tumor
Interventions: DRUG: Ramucirumab|DRUG: Cyclophosphamide|DRUG: Vinorelbine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Electrosurgical Bipolar Plasmakinetic Vessel Sealing During Abdominal Hysterectomy: A Randomized Controlled Trial
Status: COMPLETED
Conditions: Abdominal Hysterectomy for Benign Disease
Interventions: PROCEDURE: Plasmakinetic bipolar energy forceps|PROCEDURE: Abdominal Hysterectomy with traditional suture technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: "CuraMed" and "Curamin" in Osteoarthritis
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: OTHER: Placebo|DIETARY_SUPPLEMENT: Curamin|DIETARY_SUPPLEMENT: CuraMed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Anti-CD14 Treatment With IC14 in Hospitalized ARDS Patients
Status: NOT_YET_RECRUITING
Conditions: Acute Respiratory Distress Syndrome|Adult Respiratory Distress Syndrome|Acute Lung Injury|Acute Lung Injury/Acute Respiratory Distress Syndrome (ARDS)
Interventions: BIOLOGICAL: Atibuclimab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Split Face Study of the Duration of Local Anesthetics
Status: COMPLETED
Conditions: Anesthetics, Local
Interventions: DRUG: lidocaine + epinephrine 1:100,000|DRUG: Ropivacaine 0.5% Injectable Solution|DRUG: Bupivacaine 0.5% Injectable Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Pragmatic Randomized Controlled Trial: Horticultural Therapy for Inpatient Older Adults in an Acute Care Hospital
Status: COMPLETED
Conditions: Frailty|Hospitalism
Interventions: OTHER: Horticultural Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Combination Chemotherapy in Treating Young Patients With Newly Diagnosed High-Risk B Acute Lymphoblastic Leukemia and Ph-Like TKI Sensitive Mutations
Status: ACTIVE_NOT_RECRUITING
Conditions: B Acute Lymphoblastic Leukemia|B Acute Lymphoblastic Leukemia, BCR-ABL1-Like|Central Nervous System Leukemia|Testicular Leukemia
Interventions: DRUG: Clofarabine|DRUG: Cyclophosphamide|DRUG: Cytarabine|DRUG: Dasatinib|DRUG: Daunorubicin Hydrochloride|DRUG: Dexamethasone|DRUG: Doxorubicin Hydrochloride|DRUG: Etoposide|DRUG: Hydrocortisone Sodium Succinate|OTHER: Laboratory Biomarker Analysis|DRUG: Leucovorin Calcium|DRUG: Mercaptopurine|DRUG: Methotrexate|DRUG: Pegaspargase|DRUG: Prednisone|RADIATION: Radiation Therapy|DRUG: Thioguanine|DRUG: Vincristine Sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Sustained Natural Apophyseal Glides in Combination With McKenzie Extension Protocol in the Management of Discogenic Low Back Pain
Status: UNKNOWN
Conditions: Low Back Pain|Disk Prolapse|Disk Herniated Lumbar|Sciatic Radiculopathy
Interventions: PROCEDURE: Mckenzie Extension Protocol|PROCEDURE: Lumbar SNAGs|DEVICE: inferential therapy|DEVICE: Heat Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lidocaine as an Anesthetic Adjuvant in Liver and Gastric Laparoscopic Surgery
Status: RECRUITING
Conditions: Pain, Postoperative
Interventions: DRUG: Lidocaine Iv
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Theories About Myopia Progression (STAMP)
Status: COMPLETED
Conditions: Myopia
Interventions: DEVICE: progressive addition spectacle lens (bifocal)|DEVICE: Single Vision Lenses (SVLs)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Implications of Self-weighing During Weight Loss Treatment
Status: UNKNOWN
Conditions: Overweight and Obesity|Signs and Symptoms|Behavior, Eating
Interventions: BEHAVIORAL: Control Group (CG)|BEHAVIORAL: Intervention Group (IG)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Trial of Gemcitabine, Cisplatin, and Ifosfamide in Patients With Relapsed Non-Seminomatous Germ-Cell Tumors
Status: UNKNOWN
Conditions: Germ Cell Tumor
Interventions: DRUG: gemcitabine, ifosfamide, cisplatin, G-CSF
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prostatic Artery Embolization (PAE) for Treatment of Signs and Symptoms of Benign Prostatic Hyperplasia (BPH) Using Bead Block Microspheres
Status: COMPLETED
Conditions: Benign Prostatic Hyperplasia (BPH)
Interventions: DEVICE: Prostate Artery Embolization
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Selepressin Evaluation Programme for Sepsis-Induced Shock - Adaptive Clinical Trial
Status: TERMINATED
Conditions: Septic Shock
Interventions: DRUG: selepressin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Acalabrutinib + Liso-Cel In R/R Aggressive B-Cell Lymphomas
Status: RECRUITING
Conditions: Refractory Aggressive B-cell Lymphomas|Refractory B-Cell Non-Hodgkin Lymphoma|Aggressive B-cell NHL|Diffuse Large B-cell Lymphoma (DLBCL)|De Novo or Transformed Indolent B-cell Lymphoma|DLBCL, Nos Genetic Subtypes|T Cell/Histiocyte-rich Large B-cell Lymphoma|EBV-Positive DLBCL, Nos|Primary Mediastinal [Thymic] Large B-cell Lymphoma (PMBCL)|High-Grade B-Cell Lymphoma, Nos|C-MYC/BCL6 Double-Hit High-Grade B-Cell Lymphoma|Grade 3b Follicular Lymphoma|C-MYC/BCL2 Double-Hit High-Grade B-Cell Lymphoma
Interventions: DRUG: ACALABRUTINIB|DRUG: LISOCABTAGENE MARALEUCEL|DRUG: Lymphodepleting chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of an Apple Extract on Glycaemia: The GLU-Pomme Study
Status: COMPLETED
Conditions: Prevention of Hyperglycaemia
Interventions: DIETARY_SUPPLEMENT: Apple polyphenols|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Anidulafungin vs Amphotericin B Safety in High Risk Hepatic Transplant Recipients
Status: COMPLETED
Conditions: Liver Disease|Fungal Infection
Interventions: DRUG: Anidulafungin|DRUG: Liposomal amphotericin B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety of Human Papilloma Virus Vaccine in Solid Organ Transplant Recipients
Status: COMPLETED
Conditions: Late Complication From Kidney Transplant|Complication of Transplanted Liver|Human Papillomavirus-Related Carcinoma
Interventions: DRUG: Quadravalent human papillomavirus vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of ONO-4538 in Non-Squamous Non-Small Cell Lung Cancer (TASUKI-52)
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: ONO-4538|DRUG: Carboplatin|DRUG: Paclitaxel|DRUG: Bevacizumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Smart Digital Workflow Towards High Precision and Through-Put Production for Removable Partial Dentures
Status: RECRUITING
Conditions: Partial-edentulism
Interventions: DEVICE: Group 3 - 3D Printed Removable Partial Denture|DEVICE: Group 2 - 3D Printed Removable Partial Denture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of Cotadutide in Participants Who Have Chronic Kidney Disease With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus|Chronic Kidney Diseases
Interventions: DRUG: Cotadutide 100 micrograms|DRUG: Cotadutide 300 micrograms|DRUG: Cotadutide 600 micrograms|DRUG: Semaglutide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Cancer Specific Epitope Peptides Cocktail for Cervical, GI, and Lung Tumors
Status: COMPLETED
Conditions: Metastatic Tumors
Interventions: BIOLOGICAL: 5 peptide vaccines of KOC1, TTK, CO16, DEPDC1, MPHOSPH1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Combined Cycle Training and Inspiratory Muscle Training in Patients With COPD
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: DEVICE: Control group|DEVICE: calibrated cycle ergometer|DEVICE: calibrated cycle ergometer and threshold loading device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fluoxetine to Reduce Hospitalization From COVID-19 Infection (FloR COVID-19)
Status: WITHDRAWN
Conditions: Covid19
Interventions: DRUG: Fluoxetine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of 19-gauge vs 21-gauge EBUS TBNA in Assessing Thoracic Lymphadenopathy
Status: COMPLETED
Conditions: Enlarged Lymph Nodes (Excluding Infective)
Interventions: DEVICE: EBUS TBNA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Telerehabilitation in Individuals With Rotator Cuff Tear
Status: COMPLETED
Conditions: Rotator Cuff Tears|Physiotherapy and Rehabilitation|Shoulder Pain|Rotator Cuff Injuries
Interventions: OTHER: Internet Based Synchronized Telerehabilitation|OTHER: Face-to-Face Rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Immediate Effect of Irradiation With Low-level Laser Therapy on the Electromyographic Activity of the Upper Trapezius Muscles and the Level of Pain Among Patients With Non-specific Neck Pain
Status: COMPLETED
Conditions: Neck Pain Treatment
Interventions: DEVICE: low level laser therapy|DEVICE: Placebo low level laser therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pregnancy Related Inappropriate Sinus Tachycardia
Status: UNKNOWN
Conditions: Inappropriate Sinus Tachycardia|Pregnancy Related
Interventions: DIAGNOSTIC_TEST: ECG|DIAGNOSTIC_TEST: heart rate monitor|DIAGNOSTIC_TEST: Autonomic Nervous System (ANS) Activity|DIAGNOSTIC_TEST: Haemodynamic variables|OTHER: Echocardiogram
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Intradialytic Combined Exercise on Physical Outcomes in End-Stage Renal Disease Patients
Status: COMPLETED
Conditions: Kidney Failure, Chronic|Exercise|Physical Fitness
Interventions: OTHER: Usual care with sham intervention|OTHER: Intradialytic Combined Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Increasing Dose Safety Study of Hemospan in Orthopedic Surgery Patients
Status: COMPLETED
Conditions: Hypotension|Hypoxia
Interventions: DRUG: Hemospan (MP4OX)|DRUG: Ringer's lactate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Actovegin 12-Week Treatment Given First Intravenously and Subsequently Orally in Participants With Peripheral Arterial Occlusive Disease Fontaine Stage IIB
Status: COMPLETED
Conditions: Peripheral Arterial Diseases
Interventions: DRUG: Actovegin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Study of Safety, Tolerability and Pharmacokinetics of SPR994
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: SPR994|DRUG: Placebo Oral Tablet|DRUG: Orapenem®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pacing in Heart Failure With Preserved LVEF
Status: ENROLLING_BY_INVITATION
Conditions: Heart Failure
Interventions: DEVICE: CRT-pacemaker device set to Routine Medical Therapy|DEVICE: CRT-pacemaker device set to Routine Medical Therapy + LVP|DEVICE: CRT-pacemaker device set to Routine Medical Therapy + BiVP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Light Therapy for Internet Gaming Disorder
Status: COMPLETED
Conditions: Internet Gaming Disorder|Light Therapy
Interventions: OTHER: Light therapy|OTHER: Light placebo therapy|OTHER: Emotion Bias Modification Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of Zenocutuzumab (MCLA-128) in Patients With Solid Tumors Harboring an NRG1 Fusion (eNRGy)
Status: RECRUITING
Conditions: Solid Tumours Harboring NRG1 Fusion|NSCLC Harboring NRG1 Fusion|Pancreatic Cancer Harboring NRG1 Fusion|NRG1 Fusion
Interventions: DRUG: zenocutuzumab (MCLA-128)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stent Versus Conservative Treatment in Patients With Deep Venous Obstruction
Status: TERMINATED
Conditions: Deep-Venous Thrombosis|Deep Venous Stenting|Randomized Clinical Trial
Interventions: DEVICE: deep venous stenting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigation of Cecal Intubation Rates and Pain Levels Between Water Exchange and Air Insufflation Flexible Sigmoidoscopy
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: PROCEDURE: Water Exchange Sigmoidoscopy|PROCEDURE: Air Insufflation Sigmoidoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SCREENING
Clinical trial: Clorhexidine Versus Povidone for the Prevention of Surgical Site Infection After Cesarean Section
Status: COMPLETED
Conditions: Surgical Wound Infection
Interventions: PROCEDURE: Clorhexidine|PROCEDURE: Povidone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Impact of the Serratus Plane Block in Pain and the Use of Opioids in Breast Surgery
Status: COMPLETED
Conditions: Surgery|Breast Reconstruction
Interventions: PROCEDURE: Serrato|PROCEDURE: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Impact of Everolimus Based Immunosuppression in the Evolution of Hepatitis C Fibrosis After Liver Transplantation
Status: COMPLETED
Conditions: Hepatitis C Recurrence After Liver Transplant
Interventions: DRUG: EVL arm|DRUG: MMF arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: High Dose Cyclophosphamide Followed by Glatiramer Acetate in the Treatment of Relapsing Remitting Multiple Sclerosis
Status: WITHDRAWN
Conditions: Relapsing Remitting Multiple Sclerosis
Interventions: DRUG: Cyclophosphamide/Glatiramer acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Carboxyamidotriazole and Ketoconazole in Treating Patients With Advanced Cancers
Status: COMPLETED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: carboxyamidotriazole|DRUG: chemotherapy|DRUG: ketoconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pivotal Study for the FLAIR Endovascular Stent Graft
Status: COMPLETED
Conditions: Stenoses
Interventions: DEVICE: FLAIR Endovascular Stent Graft|PROCEDURE: PTA|DEVICE: FLAIR Endovascular Stent Graft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Retinal Microvascular Network and Coronary Revascularization Surgery at the Dijon University Hospital
Status: RECRUITING
Conditions: Myocardial Revascularization Surgery With Extracorporeal Circulation
Interventions: OTHER: Complete ophthalmological check-up|BIOLOGICAL: Blood sampling
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: TeleEducation for Implementing a Clinical Practice Guideline For Amputees
Status: COMPLETED
Conditions: Clinical Practice Guidelines|Lower Limb Amputation Above Knee (Injury)|Lower Limb Amputation Below Knee (Injury)|Lower Limb Amputation Knee|Lower Limb Ischemia|Diabetes Mellitus|Rehabilitation|Prosthesis User
Interventions: BEHAVIORAL: Telehealth-based strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: AZD8683 Single Ascending Dose Study
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: AZD8683|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Tolerance to Hemodialysis in Insulin-Requiring Diabetic Patients: BD vs AFB With Blood Volume Biofeedback
Status: COMPLETED
Conditions: Hypotension|Hemodialysis
Interventions: OTHER: BD and BVC, AFB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Live Microbials to Boost Anti-Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) Immunity Clinical Trial
Status: COMPLETED
Conditions: Covid19
Interventions: DIETARY_SUPPLEMENT: OL-1, standard dose|DIETARY_SUPPLEMENT: OL-1, high dose|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Pharmacokinetic (PK) Trial in Healthy Asian and Caucasian Volunteers Investigating the PK Profile of Eurartesim™
Status: COMPLETED
Conditions: Malaria, Falciparum
Interventions: DRUG: Eurartesim
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Study of Beet Root in Locally Advanced Squamous Cell Cancer of the Head and Neck
Status: COMPLETED
Conditions: Mucositis
Interventions: DRUG: Beetroot|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Psychotherapy Plus: Combining Cognitive Behavioral Therapy With tDCS
Status: COMPLETED
Conditions: Major Depression
Interventions: BEHAVIORAL: cognitive behavioral therapy|DEVICE: tDCS|DEVICE: sham-tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Safety of a New Power Exoskeleton Robot for Improving Walking Ability in Spinal Cord Injury Patients
Status: UNKNOWN
Conditions: Spinal Cord Injuries|Complete Spinal Cord Injury|Incomplete Spinal Cord Injury
Interventions: DEVICE: exoskeleton robot training
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Botulinum Toxin Augmented Surgery vs Conventional Surgery in the Management of Large Angle Horizontal Deviations
Status: UNKNOWN
Conditions: Large Angle Horizontal Strabismus
Interventions: PROCEDURE: botulinum toxin augmented surgery|PROCEDURE: conventional surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long-term Persistence of Immunity Against Hepatitis B in 7-8 Years Old Children After Hepatitis B Vaccination.
Status: COMPLETED
Conditions: Hepatitis B Vaccine
Interventions: BIOLOGICAL: Engerix™-B Kinder
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: 18-Month Study of the Efficacy of Xaliproden (SR57746A) in Patients With Mild-to-Moderate Dementia of the Alzheimer's Type
Status: COMPLETED
Conditions: Alzheimer Disease
Interventions: DRUG: xaliproden (SR57746A)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: OEA for Targeting Lipid Metabolism in GWI
Status: ACTIVE_NOT_RECRUITING
Conditions: Gulf War Illness
Interventions: DIETARY_SUPPLEMENT: Oleoylethanolamide (OEA)|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effective Consumption of Oral Nutritional Supplements in Geriatrics: A Study Evaluating a Strategy Based on a Preliminary Degustation
Status: UNKNOWN
Conditions: Malnutrition|Geriatric Patients
Interventions: OTHER: Oral nutritional supplements (ONS) degustation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: A Study to Evaluate the Safety and Tolerability, Pharmacokinetics (PK) and Pharmacodynamics (PD) of Melrilimab (GSK3772847) in Healthy Participants
Status: COMPLETED
Conditions: Healthy Volunteers|Asthma
Interventions: BIOLOGICAL: melrilimab (GSK3772847) 70 milligram (mg)|BIOLOGICAL: melrilimab (GSK3772847) 140 milligram (mg)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Trans Caesarean Intra Uterine Contraceptive Device Insertion Versus Conventional Postpartum 6 Weeks Insertion
Status: RECRUITING
Conditions: IUD
Interventions: DEVICE: IUD insertion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Vitamine D3 Supplementation in Patients With Serum Values +/- 20ng/ml
Status: TERMINATED
Conditions: Covid19|Influenza A|Influenza B|H1N1 Influenza
Interventions: DIETARY_SUPPLEMENT: Vitamine D3 supplementation|DIETARY_SUPPLEMENT: Diet and sun exposure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Family Partner Navigation for Children
Status: COMPLETED
Conditions: Health Behavior
Interventions: BEHAVIORAL: Usual care|BEHAVIORAL: Clinic-based visits|BEHAVIORAL: Standard pediatric surveillance|BEHAVIORAL: Structured, schedule-based visits|BEHAVIORAL: Enhanced pediatric surveillance|BEHAVIORAL: Technology enhanced care coordination|BEHAVIORAL: :Individually-tailored visits|BEHAVIORAL: Clinic-based visits and community visits
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Community Mobilization, Mobile Testing, Same-Day Results, and Post-Test Support for HIV in Sub-Saharan Africa and Thailand
Status: COMPLETED
Conditions: HIV Infections
Interventions: BEHAVIORAL: Community-Based HIV VCT|BEHAVIORAL: Standard clinic-based VCT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: GLP-1 Effects on Insulin and Glucagon in PTDM
Status: COMPLETED
Conditions: Post-transplant Diabetes Mellitus
Interventions: DIETARY_SUPPLEMENT: Glucagon-like peptide-1 (GLP-1)|OTHER: Isotonic saline|OTHER: Hyperglycemic clamp
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: A School-Based Intervention to Improve Social Functioning
Status: UNKNOWN
Conditions: ADHD - Combined Type
Interventions: BEHAVIORAL: Psychotherapy: 1. cognitive therapy 2.family intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neuro-pharmacological Properties of Repurposed Ketoconazole in Glioblastomas
Status: RECRUITING
Conditions: Glioblastoma|Glioblastoma Multiforme|Glioblastoma Multiforme of Brain|Glioblastoma Multiforme, Adult
Interventions: DRUG: Ketoconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Efficacy and Safety of M2951 in Participants With Relapsing Multiple Sclerosis
Status: TERMINATED
Conditions: Relapsing-remitting Multiple Sclerosis
Interventions: DRUG: Evobrutinib|DRUG: Evobrutinib|DRUG: Evobrutinib|DRUG: Placebo|DRUG: Tecfidera|DRUG: Evobrutinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: TRUST-tPA: Therapeutic Trial Evaluating Efficacy of Telemedicine (TELESTROKE) of Patients With Acute Stroke
Status: COMPLETED
Conditions: Acute Stroke
Interventions: PROCEDURE: Visio conference system connected to the Tele-stroke network
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intervention for High-normal Blood Pressure in Adults With Type 2 Diabetes-----renal Substudy
Status: WITHDRAWN
Conditions: Diabetes Mellitus, Type 2|Blood Pressure
Interventions: DRUG: Allisartan Isoproxil|DRUG: Amlodipine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Analysis of Adherence in Subjects Undergoing Differin Gel, 0.1% Treatment of Moderate to Severe Acne Vulgaris
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: Adapalene|BEHAVIORAL: frequent visits|BEHAVIORAL: electronic reminder|BEHAVIORAL: Parent reminder|BEHAVIORAL: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Butyrate on Affective Processes
Status: COMPLETED
Conditions: Emotions|Stress|Fear
Interventions: DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: Butyrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Prospective Phase 2 Trial of Cabazitaxel in Patients With Temozolomide Refractory Glioblastoma Multiforme
Status: COMPLETED
Conditions: Glioblastoma Multiforme (GBM) WHO Grade IV
Interventions: DRUG: Cabazitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Application of the Transtheoretical Model to the Frailty Elderly in the Community
Status: UNKNOWN
Conditions: Frailty
Interventions: BEHAVIORAL: Fitness and Nutrition Program for Seniors
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study Evaluating the Efficacy and Safety of Multiple Immunotherapy-Based Treatment Combinations in Patients With Metastatic Colorectal Cancer (Morpheus-CRC)
Status: TERMINATED
Conditions: Colorectal Cancer
Interventions: DRUG: Regorafenib|DRUG: Atezolizumab|DRUG: Imprime PGG|DRUG: Bevacizumab|DRUG: Isatuximab|DRUG: Selicrelumab|DRUG: Idasanutlin|DRUG: AB928|GENETIC: LOAd703
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating APG-115 as a Single Agent or in Combination With APG-2575 in Subjects With R/R T-PLL and NHL
Status: RECRUITING
Conditions: T-Prolymphocytic Leukemia|Non-Hodgkins Lymphoma
Interventions: DRUG: APG-115|DRUG: APG-2575
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Epoetin Alfa for the Treatment of Anemia Resulting From Chronic Lymphocytic Leukemia
Status: COMPLETED
Conditions: Anemia|Leukemia, Lymphocytic, Chronic|Leukemia, Lymphocytic|Cancer|Neoplasms|Quality of Life
Interventions: DRUG: epoetin alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: To Evaluate the Immunogenicity and Safety of Two Different Immunization Schedules of Rabies Vaccine (Vero Cell)
Status: COMPLETED
Conditions: Rabies Human
Interventions: BIOLOGICAL: Control vaccine|BIOLOGICAL: Experimental vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study of cPMP (Precusor Z) to Treat Molybdenum Cofactor Deficiency (MoCD) Type A
Status: WITHDRAWN
Conditions: Molybdenum Cofactor Deficiency Type A
Interventions: DRUG: cPMP
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Conscious Behavior Under Low-frequency Deep Brain Stimulation in Chronic and Severe Post-coma Disorders of Consciousness
Status: COMPLETED
Conditions: Chronic and Severe Post-coma Disorders of Consciousness (Permanent Vegetative State, Minimally Conscious State)
Interventions: OTHER: Implantable neurostimulation system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Medication Development in Alcoholism: Apremilast Versus Placebo
Status: COMPLETED
Conditions: Alcohol Use Disorder
Interventions: DRUG: Apremilast|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Autogenous Ramus Bone Block Harvesting With Piezosurgery
Status: COMPLETED
Conditions: Alveolar Bone Resorption
Interventions: DEVICE: Bone harvesting from ramus area with piezosurgery for autogenous bone augmentation|DEVICE: Bone harvesting from ramus area with conventional burs for autogenous bone augmentation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Stimulation With Bethanechol in Combination With Gemcitabine and Nab-paclitaxel in Pancreatic Adenocarcinoma
Status: RECRUITING
Conditions: Pancreas Cancer
Interventions: DRUG: Bethanechol|DRUG: Gemcitabine|DRUG: nab-paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: EAA/Therapy for Treating Children With ADHD
Status: UNKNOWN
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: BEHAVIORAL: EAA/T|DRUG: Methylphenidate|DRUG: Atomoxetine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of a Single Osteopathic Manipulative Treatment (OMT) on Intraocular Pressure (IOP) Reduction
Status: ENROLLING_BY_INVITATION
Conditions: Glaucoma
Interventions: PROCEDURE: Osteopathic Manipulative Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Timolol for the Prevention of Proliferation of Infantile Hemangioma (TiPPIH Trial)
Status: TERMINATED
Conditions: Infantile Hemangioma|Very Low Birth Weight Infants
Interventions: DRUG: topical 0.5% Timolol maleate|DRUG: Control (placebo) group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of Peripheral and Cerebral Arterial Flow in Acute Ischemic Stroke: Fimasartan vs. Valsartan vs. Atenolol
Status: UNKNOWN
Conditions: Blood Pressure|Ischemic Stroke
Interventions: DRUG: Fimasartan|DRUG: Valsartan|DRUG: Atenolol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Potential Therapeutic Effects of Psychedelic, N, N-dimethyltryptamine (DMT), on Alcohol Use Disorder (AUD)
Status: NOT_YET_RECRUITING
Conditions: Alcohol Use Disorder (AUD)|Alcohol-Related Disorders|Alcohol Use
Interventions: DRUG: 0.3mg/kg/min Dimethyltryptamine + Normal Saline infusion|DRUG: 0.2 mg/kg/min + Dimethyltryptamine 0.01mg/kg/min infusion|DRUG: 25 mg Diphenhydramine (5 min) + Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Clinical Evaluation of Cast21 Short Arm Product During Treatment of Distal Radial or Distal Ulnar Fractures
Status: NOT_YET_RECRUITING
Conditions: Fractures, Closed|Fractures Bone|Fracture|Fractures|Radius; Fracture, Lower or Distal End|Ulna Fractures|Radius Distal Fracture
Interventions: DEVICE: Cast or brace alternative
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Venlafaxine 25 mg Tablets Under Non-Fasting Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Venlafaxine 25 mg Tablets|DRUG: Effexor® 25 mg Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Analysis of Postural Control in Children Suffering From Triceps Suralis Shortening.
Status: COMPLETED
Conditions: Ankle Disease
Interventions: PROCEDURE: Streching Group|PROCEDURE: Heel group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Developing a Intervention to Enhance Motivation for Physical Activities Known to Reduce Fall Risk
Status: COMPLETED
Conditions: Accidental Falls|Sedentary Lifestyle
Interventions: BEHAVIORAL: 1 Physical Activity|BEHAVIORAL: Interpersonal Motivation|BEHAVIORAL: Intrapersonal Motivation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: UHCDS a-tDCS Combined With Therapeutic Exercise in Fibromyalgia Patients
Status: COMPLETED
Conditions: Fibromyalgia
Interventions: DEVICE: Real UHCDS a-tDCS|DEVICE: Therapeutic exercise|DEVICE: Sham UHCDS a-tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT