pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Mobile Phone Effects on Umbilical Artery Doppler and Heart Rate Tracing
Status: COMPLETED
Conditions: Umbilical Artery Doppler|Fetal Heart Rate Tracing
Interventions: RADIATION: mobile phone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Reveal Chagas: Clinical Evidence of the Implantable Cardiac Monitor in Patients With Chagas Disease
Status: TERMINATED
Conditions: Chagas Disease|Heart Diseases
Interventions: DEVICE: Implantable Cardiac Monitor|PROCEDURE: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GORE VIABAHN® Versus Plain Old Balloon Angioplasty (POBA) for Superficial Femoral Artery (SFA) In-Stent Restenosis
Status: COMPLETED
Conditions: Peripheral Vascular Disease
Interventions: DEVICE: GORE VIABAHN® Endoprosthesis|DEVICE: Plain old balloon angioplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy With or Without Ganitumab in Treating Patients With Newly Diagnosed Metastatic Ewing Sarcoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Ewing Sarcoma|Metastatic Malignant Neoplasm in the Bone|Metastatic Malignant Neoplasm in the Bone Marrow|Metastatic Malignant Neoplasm in the Lung|Metastatic Peripheral Primitive Neuroectodermal Tumor of Bone|Peripheral Primitive Neuroectodermal Tumor of Soft Tissues
Interventions: DRUG: Cyclophosphamide|DRUG: Doxorubicin|DRUG: Doxorubicin Hydrochloride|DRUG: Etoposide|DRUG: Etoposide Phosphate|RADIATION: External Beam Radiation Therapy|BIOLOGICAL: Ganitumab|DRUG: Ifosfamide|RADIATION: Stereotactic Radiosurgery|PROCEDURE: Therapeutic Surgical Procedure|DRUG: Vincristine|DRUG: Vincristine Sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vildagliptin for Treatment of Antipsychotic-induced Dyslipidemia
Status: RECRUITING
Conditions: Schizophrenia|Dyslipidemias
Interventions: DRUG: Vildagliptin 50 MG|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Does Wearing Tetra-Grip Improve Arm Function in Children Diagnosed With Neonatal Brachial Plexus Palsy?
Status: TERMINATED
Conditions: Neonatal Brachial Plexus Palsy
Interventions: DEVICE: Tetra-grip
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acupuncture for Phantom Limb Pain
Status: SUSPENDED
Conditions: Phantom Limb Pain
Interventions: PROCEDURE: acupuncture|OTHER: placebo/sham acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Oral Tramadol Administration Prior to IUD Insertion
Status: UNKNOWN
Conditions: Contraception
Interventions: DRUG: oral tramadol|DRUG: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: An Exploratory Study of Tramadol Hydrochloride in Patients With Osteoarthritis of the Knee or Low Back Pain
Status: COMPLETED
Conditions: Osteoarthritis|Low Back Pain
Interventions: DRUG: Tramadol Hydrochloride; JNS013
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Of Cisplatin (Or Carboplatin) And Etoposide With Or Without Figitumumab (CP-751,871) In Patients With Extensive-Stage Small Cell Lung Cancer
Status: TERMINATED
Conditions: Small Cell Lung Carcinoma
Interventions: DRUG: figitumumab|DRUG: Cisplatin (Or Carboplatin)|DRUG: Etoposide|DRUG: Cisplatin (Or Carboplatin)|DRUG: Etoposide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety of Phenylephrine Hydrochloride, Acetaminophen, Dimethindene Maleate Compared to Phenylephrine Hydrochloride Alone in Healthy Volunteers
Status: WITHDRAWN
Conditions: Heart Rate|Blood Pressure|Arrhythmias
Interventions: DRUG: Phenylephrine HCL|DRUG: Phenylephrine HCL/Acetaminophen/Dimethindene Maleate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose:
Clinical trial: High Dose Inorganic Selenium for Preventing Chemotherapy Induced Peripheral Neuropathy
Status: ACTIVE_NOT_RECRUITING
Conditions: Chemotherapy-induced Peripheral Neuropathy|Recurrent Ovarian Carcinoma|Ovarian Cancer|Fallopian Tube Cancer|Primary Peritoneal Carcinoma
Interventions: DRUG: sodium selenite pentahydrate|DRUG: Normal saline|DRUG: Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluating the Role of the Guidewire in Peripheral Intravenous Access: A Randomized Controlled Trial of Ultrasound-Guided Catheter Survival
Status: RECRUITING
Conditions: Peripheral Intravenous Vein Catheter Phlebitis|Intravenous Infection
Interventions: DEVICE: B. Braun 6.35cm 20 gauge ultralong intravenous catheter|DEVICE: BD 5.71 cm 20 gauge Accucath
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Effect of Acupressure and Mindfulness to Cope With Premenstrual Syndrome (PMS) on PMS and Quality of Life
Status: COMPLETED
Conditions: Premenstrual Syndrome
Interventions: PROCEDURE: Acupresur|PROCEDURE: Mindfulness|PROCEDURE: Plasebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Corticosteroids/β2-agonists in Hair in Asthmatic Patients (CorticHair)
Status: UNKNOWN
Conditions: Asthma
Interventions: OTHER: Hair sampling|DIAGNOSTIC_TEST: Hair's drug concentrations
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effect of Low-impact Aerobic Exercise and Music Therapy in Fibromyalgia
Status: COMPLETED
Conditions: Fibromyalgia
Interventions: OTHER: Low-impact aerobic exercise combined with music therapy|OTHER: Low-impact aerobic exercise|OTHER: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Improving Cardiac Rehabilitation Outcomes Through Mobile Case Management (iCARE)
Status: RECRUITING
Conditions: Acute Myocardial Infarction|Acute Coronary Syndrome|Stable Angina Pectoris|Percutaneous Coronary Intervention|Heart Failure
Interventions: OTHER: Center-Based Cardiac Rehab|OTHER: mHealth|OTHER: Home-Based Cardiac Rehab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Mechanisms to Reduce Mental and Physical Fatigue Following Exercise Training in Older Adults
Status: COMPLETED
Conditions: Fatigue|Aging
Interventions: DIETARY_SUPPLEMENT: BCAA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Mom and Infant Outcomes (MOMI) Study
Status: RECRUITING
Conditions: Postpartum Depression|Postpartum Anxiety|Cardiometabolic Syndrome
Interventions: BEHAVIORAL: MOMI PODS|BEHAVIORAL: Enhanced Usual Care (EUC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Phase 1/2 Clinical Trial to Evaluate the Safety, Tolerability, Dosimetry, and Anti-tumor Activity of Ga-68-NGUL / Lu-177-DGUL in Patients With Metastatic Castration-resistant Prostate Cancer (mCRPC) Refractory to Standard Therapy
Status: RECRUITING
Conditions: Prostate Cancer|mCRPC
Interventions: DRUG: Lu-177-DGUL|DRUG: Ga-68-NGUL
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study for Evaluating the Efficacy and Safety of Zonisamide and Lamotrigine (Lamictal) for Subjects With Refractory Simple Partial, Complex Partial or Partial With Secondary Generalized Seizures
Status: COMPLETED
Conditions: Epilepsy
Interventions: DRUG: Zonisamide|DRUG: Lamotrigine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Continued Access Study to Evaluate Performance of the Organ Recovery Systems _LifePort® Liver Transporter System, a Machine Perfusion System, for Liver Transplant (PILOT™_CA)
Status: RECRUITING
Conditions: Liver Transplantation
Interventions: DEVICE: Hypothermic Machine Perfusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combined Activity and Cognitive Intervention for ICU Survivors
Status: ENROLLING_BY_INVITATION
Conditions: Post Intensive Care Syndrome|ARDS: Acute Respiratory Distress Syndrome|Delirium|Loss of Muscle Mass|Loss of Muscle Strength|Cognitive Function
Interventions: OTHER: Attention Placebo|OTHER: Home-based exercises combined with cognitive training|OTHER: Home-based exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Ranibizumab Intravitreal Injections in Patients With Visual Impairment Due to Macular Edema Secondary to Central Retinal Vein Occlusion
Status: COMPLETED
Conditions: Macular Edema|Central Retinal Vein Occlusion
Interventions: DRUG: Ranibizumab 0.5 mg/0.05 ml
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CAR-T Cells in the Treatment of Malignant Hematological Tumors
Status: RECRUITING
Conditions: Lymphoma, B-Cell|Leukemia, B-cell|Leukemia, T-Cell|Multiple Myeloma
Interventions: BIOLOGICAL: CAR-T
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Decompression vs Physical Training for the Treatment of Lumbar Spinal Stenosis
Status: COMPLETED
Conditions: Spinal Stenosis|Spinal Stenosis Lumbar|Degeneration Lumbar Spine|Degeneration Spine|Neurogenic Claudication Co-Occurrent and Due to Spinal Stenosis of Lumbar Region|Pseudoclaudication Syndrome
Interventions: PROCEDURE: Decompression
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Phase I Study of AC220 in Patients With Relapsed/Refractory Acute Myeloid Leukemia Regardless of FLT3 Status
Status: COMPLETED
Conditions: Acute Myeloid Leukemia|Leukemia|Myelodysplastic Syndrome|AML|MDS
Interventions: DRUG: AC220
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of PG101 for Dry Eye Syndrome
Status: COMPLETED
Conditions: Dry Eye Syndrome
Interventions: DRUG: PG101
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ultrasound in Tongue Cancer- a Help to Decide Depth of Invasion and to Improve the Surgical Margin
Status: COMPLETED
Conditions: Tongue Cancer|Floor of Mouth Squamous Cell Carcinoma
Interventions: DIAGNOSTIC_TEST: Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Setting Families on a Positive Path to Recovery After Pediatric TBI: Road-to-Recovery
Status: RECRUITING
Conditions: Traumatic Brain Injury|Head Injury|Head Injuries, Closed|Brain Hemorrhage, Traumatic|Brain Edema|Intracranial Edema
Interventions: BEHAVIORAL: Road-to-recovery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of ASP8273 vs. Erlotinib or Gefitinib in First-line Treatment of Patients With Stage IIIB/IV Non-small Cell Lung Cancer Tumors With EGFR Activating Mutations
Status: TERMINATED
Conditions: Non-small Cell Lung Cancer (NSCLC)
Interventions: DRUG: naquotinib mesilate|DRUG: Erlotinib|DRUG: Gefitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hypofractionated Radiotherapy and Concurrent Cisplatin for Head and Neck Cancer
Status: UNKNOWN
Conditions: Radiotherapy; Complications
Interventions: RADIATION: Hypofractionated Radiotherapy|DRUG: Weekly cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Baclofen Treatment on Nocturnal Muscle Cramps in Patients With Lumbar Spinal Stenosis: a Randomized Clinical Trial
Status: COMPLETED
Conditions: Lumbar Spinal Stenosis With Nocturnal Calf Cramps
Interventions: DRUG: gabapentin (neurontin® capsule 300mg) treatment|DRUG: baclofen (baclofen Tab. 10mg) treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Rebamipide 2% Versus Autologous Serum
Status: COMPLETED
Conditions: Dry Eye Syndromes|Sjögren Syndrome
Interventions: DRUG: Rebamipide|BIOLOGICAL: autologous serum|OTHER: autologous serum and rebamipide 2%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Excipients on Pharmacokinetics of OXPzero(TM) Ibuprofen
Status: COMPLETED
Conditions: Pharmacokinetics
Interventions: DRUG: Ibuprofen|DRUG: Ibuprofen Lysine|DRUG: Ibuprofen-LDH
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Prospective Study on Embolization of Intracranial Aneurysms With Pipeline™ Embolization Device
Status: COMPLETED
Conditions: Intracranial Aneurysm
Interventions: DEVICE: Pipeline™ Embolization Device/ Pipeline™Flex Embolization Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Surgery to Remove the Sentinel Lymph Node and Axillary Lymph Nodes After Chemotherapy in Treating Women With Stage II, Stage IIIA, or Stage IIIB Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: systemic chemotherapy|PROCEDURE: axillary lymph node dissection|PROCEDURE: neoadjuvant therapy|PROCEDURE: sentinel lymph node biopsy|PROCEDURE: therapeutic conventional surgery|PROCEDURE: ultrasound imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Autologous Platelet Concentrate (APC) in Intrabony Defects
Status: RECRUITING
Conditions: Periodontal Diseases
Interventions: PROCEDURE: Simplified Papilla Preservation Flap (SPPF) and PRGF ENDORET (PRGF ENDORET®-KMU16)|PROCEDURE: Simplified Papilla Preservation Flap (SPPF) and GTR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of The Combined Ablation Procedure To Treat Longstanding Persistent Atrial Fibrillation
Status: TERMINATED
Conditions: Atrial Fibrillation
Interventions: DEVICE: Numeris®-AF Guided Coagulation System with VisiTrax®
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Combination of Brompheniramine and Phenylephrine for the Symptoms Relief of Rhinitis
Status: COMPLETED
Conditions: Nasal Congestion and Inflammations|Rhinitis
Interventions: DRUG: Group 1|DRUG: Group 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Intraarticular Injections of Hyalgan in the Treatment of Osteoarthritis of the Knee
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DEVICE: Hyalgan|DEVICE: sterile normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Study To Evaluate The Effect Of CP-690,550 On Measures Of Kidney Function In Patients With Active Rheumatoid Arthritis
Status: COMPLETED
Conditions: Arthritis, Rheumatoid
Interventions: DRUG: CP-690,550 or Placebo|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Vemurafenib With Sorafenib Tosylate or Crizotinib in Treating Patients With Advanced Malignancies With BRAF Mutations
Status: COMPLETED
Conditions: Advanced Malignant Neoplasm|BRAF Gene Mutation|Metastatic Malignant Neoplasm|Recurrent Malignant Neoplasm|Refractory Malignant Neoplasm
Interventions: DRUG: Crizotinib|OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacological Study|DRUG: Sorafenib Tosylate|DRUG: Vemurafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety and Efficacy of KITE-585 in Participants With Relapsed/Refractory Multiple Myeloma
Status: TERMINATED
Conditions: Relapsed/Refractory Multiple Myeloma
Interventions: GENETIC: KITE-585|DRUG: Cyclophosphamide|DRUG: Fludarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of RO5024048 in Combination With Pegasys and Copegus in Treatment-Naive Patients With Chronic Hepatitis C, Genotype 1 or 4
Status: COMPLETED
Conditions: Hepatitis C, Chronic
Interventions: DRUG: Copegus|DRUG: Copegus|DRUG: Pegasys|DRUG: Pegasys|DRUG: RO5024048|DRUG: RO5024048|DRUG: RO5024048|DRUG: RO5024048
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Volar Locking Plate Versus External Fixator/Cast Fixation for the Treatment of Distal Radius Fractures
Status: COMPLETED
Conditions: Distal Radius Fractures
Interventions: PROCEDURE: volar locking plating|PROCEDURE: external immobilisation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate NBI-6024 in Adult and Adolescent Patients With New Onset of Type 1 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus
Interventions: DRUG: NBI-6024
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Interest of a Simulated Procedure Performed on a Printed Model in the Endovascular Treatment of Carotid-sylvian Aneurysms
Status: NOT_YET_RECRUITING
Conditions: Aneurysm Cerebral
Interventions: OTHER: Operational Pre-Planning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Bright Light Therapy for Non-motor Symptoms in Parkinson's Disease
Status: RECRUITING
Conditions: Parkinson Disease
Interventions: DEVICE: Bright light therapy|DEVICE: Inactivated negative ion generator|DEVICE: Inactivated negative ion generator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Safety, Tolerability, and Efficacy of BxC-I17e Single and Multiple Dose SC Injection in Patients With Moderate to Severe Atopic Dermatitis
Status: RECRUITING
Conditions: Atopic Dermatitis
Interventions: DRUG: BxC-I17e|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Binaural Beat Technology and Rhythmical Photic Stimulation
Status: COMPLETED
Conditions: Depression
Interventions: OTHER: Sound and light therapy (BBT and FL group)|OTHER: Sound therapy group (BBT)|OTHER: Relaxing music group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Efficacy, Safety, and Tolerability of Dupilumab in Patients With Persistent Moderate to Severe Eosinophilic Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Dupilumab|DRUG: Placebo (for Dupilumab)|DRUG: Fluticasone/Salmeterol combination therapy|DRUG: Fluticasone monotherapy|DRUG: Albuterol|DRUG: Levalbuterol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Vascular Alteration and Evolution of Cognitive Impairment
Status: COMPLETED
Conditions: Cognitive Impairment
Interventions: BIOLOGICAL: blood sampling|PROCEDURE: brain MRI and TEP cerebral|OTHER: Assessment of cognitive functions|OTHER: Electrocardiogram and blood pressure|PROCEDURE: Vascular explorations|BIOLOGICAL: Urine sample
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: HLA-A2-Restricted Glioma Antigen-Peptides Vaccinations With Poly-ICLC for Recurrent WHO Grade II Gliomas
Status: COMPLETED
Conditions: Astrocytoma|Oligoastrocytoma|Oligodendroglioma
Interventions: BIOLOGICAL: Peptide vaccine + Poly-ICLC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Of PF-05212384 In Combination With Other Anti-Tumor Agents and in Combination With Cisplatin in Patients With Triple Negative Breast Cancer in an Expansion Arm (TNBC)
Status: COMPLETED
Conditions: Neoplasm
Interventions: DRUG: PF-05212384 (gedatolisib)|DRUG: Docetaxel|DRUG: Cisplatin|DRUG: Dacomitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Risdiplam in Patients With Spinal Muscular Atrophy Previously Treated With Nusinersen
Status: ACTIVE_NOT_RECRUITING
Conditions: Spinal Muscular Atrophy
Interventions: DRUG: Risdiplam
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vitamin A and Maternal-infant Flu Vaccine Response
Status: COMPLETED
Conditions: Influenza
Interventions: DIETARY_SUPPLEMENT: Vitamin A|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Frequency and Magnitude of Subclinical Systolic Dysfunction by Strain Imaging in Heart Failure With Preserved Ejection Fraction
Status: COMPLETED
Conditions: Heart Failure|Heart Failure With Preserved Ejection Fraction
Interventions: DIAGNOSTIC_TEST: 2d speckle tracking echocardiography|DIAGNOSTIC_TEST: serum BNP level
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical Evaluation of Adjusted Doses of Darunavir/Ritonavir With Rifampicin in HIV-infected Volunteers
Status: TERMINATED
Conditions: HIV Infections
Interventions: DRUG: Darunavir/ritonavir 800/100 mg tablet|DRUG: Rifampicin 600mg QD tablet and DTG 50mg BD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Trimodality Approach of Low Dose iOnizing Radiation With or Without Neoadjuvant Pembrolizumab and Prostatectomy for Men With Intermediate/High Risk Prostate Cancer (TALON)
Status: NOT_YET_RECRUITING
Conditions: Prostate Cancer
Interventions: DRUG: pembrolizumab|RADIATION: Stereotactic body radiation therapy|DRUG: Short-term androgen deprivation therapy|PROCEDURE: Radical Prostatectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Eganelisib as Monotherapy and in Combination With Cytarabine in Relapsed/Refractory AML
Status: NOT_YET_RECRUITING
Conditions: AML, Adult|MDS
Interventions: DRUG: Eganelisib|DRUG: Eganelisib in combination with cytarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics, Safety, Tolerability and Efficacy of Intravenous Doses of ZGN-433 in Obese Female Volunteers
Status: COMPLETED
Conditions: Obesity
Interventions: DRUG: ZGN-433|DRUG: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Propofol-Fentanyl-Dexmedetomidine and Propofol-Fentanyl-Sevoflurane Anesthesia for Major Spine Surgery Under Somato Sensory- and Motor- Evoked Potential Monitoring
Status: RECRUITING
Conditions: Propofol|Fentanyl|Dexmedetomidine|Sevoflurane|Spine Surgery|Somatosensory Evoked Potential|Motor Evoked Potential
Interventions: DRUG: Propofol-Fentanyl|DRUG: Propofol-Fentanyl-Dexmedetomidine|DRUG: Propofol-Fentanyl-Sevoflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Cognitive Behavioral Therapy, Modafinil, or Both for Multiple Sclerosis Fatigue
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: BEHAVIORAL: Telephone-based Cognitive Behavioral Therapy|DRUG: Modafinil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 18F-FluorThanatrace (PET/CT) in Glioblastoma
Status: TERMINATED
Conditions: Glioblastoma
Interventions: DRUG: 18F-FluorThanatrace
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effects Of Fish Oil Emulsion On Severe Acute Pancreatitis Patients
Status: COMPLETED
Conditions: Assess Effect of Omega-3 Fish Oil in Patients With Severe Acute Pancreatitis
Interventions: DIETARY_SUPPLEMENT: Lipidem (Omega-3 fish oil lipid emulsion)|DIETARY_SUPPLEMENT: Lipofundin® MCT/LCT 20%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of AGN-151586 in Japanese Participants With Moderate to Severe Glabellar Lines
Status: COMPLETED
Conditions: Moderate to Severe Glabellar Lines
Interventions: DRUG: AGN-151586|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating Absorption, Distribution, Metabolism and Excretion (ADME) of Single Dose [14C] Selumetinib in Volunteers
Status: COMPLETED
Conditions: Solid Tumours
Interventions: DRUG: [C14] selumetinib (oral)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Quality Improvement and Practice Based Research in Neurology Using the EMR
Status: ENROLLING_BY_INVITATION
Conditions: Brain Tumors|Epilepsy|Migraine|Mild Cognitive Impairment|Concussion|Multiple Sclerosis|Neuropathy|Parkinson's|Restless Legs Syndrome|Stroke
Interventions: DRUG: Listed for each disorder below, up to three drugs per disorder (too many characters to list in this field; see Intervention Description)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: One and Two Doses of Oxfendazole Versus a Schedule of Two Doses of Triclabendazole in Chronic Fascioliasis
Status: NOT_YET_RECRUITING
Conditions: Fascioliasis
Interventions: DRUG: Oxfendazole|DRUG: Triclabendazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: At-Home COVID-19 Antibody Test Usability Assessment & Behavior Change Study
Status: UNKNOWN
Conditions: COVID19|COVID-19|Coronavirus
Interventions: DEVICE: Premier Biotech COVID-19 IgG/IgM Rapid test Cassette
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Effects of Inhaled Nitric Oxide in the Treatment of Acute Hypoxemic Respiratory Failure (AHRF) in Pediatrics
Status: TERMINATED
Conditions: Respiratory Insufficiency|Anoxemia
Interventions: DRUG: Nitrogen gas|DRUG: inhaled nitric oxide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy / Radiotherapy in Uterine Cervical Neoplasms
Status: COMPLETED
Conditions: Uterine Cervical Neoplasms
Interventions: RADIATION: Chemotherapy and concomitant radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Congrong Runtong Oral Liquid in the Treatment of Functional Constipation (Yang-deficiency Type)
Status: NOT_YET_RECRUITING
Conditions: Functional Constipation
Interventions: DRUG: Congrong Runtong oral liquid|DRUG: Placental Congrong Runtong oral liquid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: COVID-19: Safety and Immunogenicity of a Reduced Dose of the BioNTech/Pfizer BNT162b2 Vaccine
Status: COMPLETED
Conditions: Covid19
Interventions: DIAGNOSTIC_TEST: immunogenicity after first and second dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Dual-Energy CT on Plan Quality, Dose-delivery Accuracy, and Simulated Outcomes of Patients Treated With Proton or Photon Therapy
Status: TERMINATED
Conditions: Lung Cancer|Brain Cancer|Head and Neck Cancer
Interventions: DEVICE: Siemens Somatom Definition Edge|DEVICE: Philips Brilliance Big Bore CT/simulator
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Analgesic Effect of Electroacupuncture on Postherpetic Neuralgia
Status: RECRUITING
Conditions: Postherpetic Neuralgia
Interventions: OTHER: Electroacupuncture treatment|OTHER: Sham electroacupuncture treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Trial of CIML NK Cell Infusion for Myeloid Disease Relapse After Hematopoietic Cell Transplantation
Status: ENROLLING_BY_INVITATION
Conditions: Acute Myeloid Leukemia|Myelodysplastic Syndromes|Myeloproliferative Neoplasm|Juvenile Myelomonocytic Leukemia
Interventions: BIOLOGICAL: CIML NK|DRUG: Fludarabine|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Freeze-dried Bovine Hydroxyapatite/Secretome Composite for Bone Defects
Status: UNKNOWN
Conditions: Bone Loss
Interventions: PROCEDURE: ORIF + autograft|PROCEDURE: ORIF + FD BHA/Secretome
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nitric Oxide in Myocardial Infarction Size
Status: TERMINATED
Conditions: Acute Myocardial Infarction|ST Elevation MI|STEMI
Interventions: DRUG: Nitric Oxide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Role of Liquid Biopsies in HPV-associated Cancer Treatment Monitoring
Status: RECRUITING
Conditions: Cervical Cancer|Cervical Dysplasia|Oropharyngeal Cancer|Human Papillomavirus Infection
Interventions: DIAGNOSTIC_TEST: Arm A - Diagnostic test: HPV detection in liquid biopsies|DIAGNOSTIC_TEST: Arm B - Diagnostic test: HPV detection in liquid biopsies
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Flash Glucose Measure System and Continuous Subcutaneous Insulin Infusion Therapy in Poorly Controlled Diabetes Type 1 Patients
Status: COMPLETED
Conditions: Glucose Metabolism Disorders (Including Diabetes Mellitus)|Diabetes Mellitus, Type 1
Interventions: DEVICE: Insulin Pump and flash glucose monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: |Primary Purpose: TREATMENT
Clinical trial: Effect of Specific Immunotherapy to Dust Mites in Children With Asthma
Status: UNKNOWN
Conditions: Asthma
Interventions: BIOLOGICAL: subcutaneous immunotherapy (House Dust Mites)|OTHER: placebo of subcutaneous immunotherapy (House Dust Mites)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Study of the Use of Neoadjuvant Cabazitaxel With Hormonal Treatment in Patients Operable Prostate Cancer, Assess the Efficacy and Toxicity of Cabazitaxel, and Explore Potential Predictive and Prognostic Markers of Clinical Outcome
Status: NOT_YET_RECRUITING
Conditions: Prostate Cancer
Interventions: DRUG: Cabazitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adefovir Dipivoxil Tablets (10mg) In Chinese Subjects With HBe Antigen Negative Chronic Hepatitis B
Status: COMPLETED
Conditions: Chronic Hepatitis B
Interventions: DRUG: adefovir dipivoxil tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of IW-1973 (A Stimulator of Soluble Guanylate Cyclase (sGC)) in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: IW-1973|DRUG: Matching Placebo Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Drug Coated Balloon For Treating the Side Branch in Complex Bifurcation Lesions
Status: UNKNOWN
Conditions: Coronary Artery Disease
Interventions: DEVICE: Drug coated balloon for the side brunch|DEVICE: Conventional balloon for the side brunch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Anticaries Effect of Xylitol,Probiotic and Chlorhexidine Mouth Rinses Among Individuals at High Risk
Status: COMPLETED
Conditions: Cariostatic Agents|Mouthwashes
Interventions: DRUG: Chlorhexidine mouthwash|DRUG: Xylitol|DRUG: Probiotic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study and Treatment of Visual Dysfunction and Motor Fatigue in Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis|Internuclear Ophthalmoplegia|Fatigue
Interventions: DRUG: Dalfampridine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of the Lung Capillary Blood Volume in Children With Sickle Cell Disease
Status: COMPLETED
Conditions: Sickle Cell Disease
Interventions: OTHER: NO-CO inhalation and expiration|OTHER: NO-CO inhalation and expiration
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Emulation of the Moderate Alcohol and Cardiovascular Health Trial (MACH15)
Status: COMPLETED
Conditions: Myocardial Infarction|Ischemic Stroke|Angina Pectoris|Coronary Revascularization|All-cause Mortality|Cardiovascular Death|Type 2 Diabetes|Heart Failure|Atrial Fibrillation|Cancer|Dementia|Depression|Infections|Injuries|Liver Cirrhosis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Cellular Pharmacology and Platelet Effects of Abacavir and Lamivudine Anabolites
Status: COMPLETED
Conditions: HIV-1-infection
Interventions: OTHER: Blood collection|DRUG: Abacavir/lamivudine|DRUG: Tenofovir alafenamide/emtricitabine|DRUG: Switch
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study Evaluating the Safety and Efficacy of Intra-articular Injections of TPX-100 in Subjects With Mild to Moderate Patello-Femoral Osteoarthritis Involving Both Knees
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: DRUG: TPX-100 50mg|DRUG: TPX-100 100mg|DRUG: TPX-100 200mg|DRUG: TPX-100 20mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of GSK2838232 in Human Immunodeficiency Virus (HIV)-1 Infected Adults
Status: COMPLETED
Conditions: Infection, Human Immunodeficiency Virus|HIV Infections
Interventions: DRUG: GSK2838232|DRUG: Cobicistat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Can Branched Chain Amino Acids Supplementation Reduce Muscle Damage Induced by Neuromuscular Electrical Stimulation? A Combined Functional and Metabolic Non-invasive Investigation in Healthy Humans
Status: COMPLETED
Conditions: Neuromuscular Electrical Stimulation
Interventions: DIETARY_SUPPLEMENT: branched-chain amino acids (BCAA) supplementation|DRUG: PLACEBO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Intravenousimmunoglobulin (IVIg) for the Treatment of Inflammatory Myopathies
Status: COMPLETED
Conditions: Dermatomyositis|Inclusion Body Myositis|Polymyositis
Interventions: DRUG: Gamma Globulin
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Efficacy of Cricoid Pressure in Occluding the Esophageal Entrance: A Glidescope ® Study
Status: COMPLETED
Conditions: Aspiration
Interventions: OTHER: cricoid pressure
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Music to Reduce Use of Smoking in Patients With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia|Nicotine Dependence|Smoking, Tobacco
Interventions: BEHAVIORAL: Music session
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Atomoxetine for Treating Marijuana-Abusing Adolescents Who Have Attention Deficit Hyperactivity Disorder
Status: COMPLETED
Conditions: Attention Deficit Disorder With Hyperactivity|Marijuana Abuse
Interventions: DRUG: Atomoxetine|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Pharmacokinetic Study of Saquinavir New Tablet Formulation in HIV-infected Pregnant Women.
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Saquinavir and Ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Emodepside Phase II Trial for Treatment of Onchocerciasis
Status: ACTIVE_NOT_RECRUITING
Conditions: Onchocerciasis
Interventions: DRUG: emodepside|DRUG: matching placebo of emodepside|DRUG: ivermectin|DRUG: matching placebo of ivermectin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Pragmatic Trial of an Active Choice Nudge for Generalist or Specialist Palliative Care for Seriously Ill Inpatients
Status: ENROLLING_BY_INVITATION
Conditions: Palliative Care
Interventions: BEHAVIORAL: Generalist + Specialist palliative care|BEHAVIORAL: Pre-Intervention phase
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effects of Comorbid Personality Disorder on the Treatment of Bipolar I Disorder
Status: COMPLETED
Conditions: Bipolar I Disorder|Borderline Personality Disorder
Interventions: BEHAVIORAL: Interpersonal Social Rhythm Therapy (IPSRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Study is Enrolling Kids From 8 to 17 Years Old. The BreathSmart Device Attaches to the Inhaler to Measure Adherence.
Status: COMPLETED
Conditions: Asthma
Interventions: DEVICE: BreatheSmart System|OTHER: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Bedside Measurement of Ventilation With or Without a One-way Valve During Lung Lavage
Status: COMPLETED
Conditions: Intensive Care
Interventions: DEVICE: CSC100 - Verso airway access adapter CareFusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Intraoperative Application of Fluorescein Sodium Angiography in Vascular Retinopathy
Status: NOT_YET_RECRUITING
Conditions: Vascular Retinopathy of Left Eye (Disorder)|Vascular Retinopathy of Right Eye (Disorder)|Diabetic Retinopathy|Retinal Vein Occlusion|Retinal Vasculitis|Vitreous Hemorrhage
Interventions: PROCEDURE: Intraoperative Fluorescein Angiography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Impact of a VR-Based Learning Tool on Nursing Students' Skills in Thorax and Lung Examination
Status: COMPLETED
Conditions: Nurse's Role|Nurse-Patient Relations|Exanimation
Interventions: OTHER: Virtual Reality-Based Learning Tool|OTHER: Traditional Small Group Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Painless Laser Therapy for Overactive Bladder
Status: UNKNOWN
Conditions: Overactive Bladder
Interventions: DEVICE: LCT-1000TM (Manufacturer: LiteCure)|DEVICE: LCT-1000TM (Manufacturer: LiteCure)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Rhomboid Intercostal Block Combined With Sub-Serratus Plane Block Versus Erector Spinae Plane Block
Status: UNKNOWN
Conditions: Rib Fractures
Interventions: PROCEDURE: ultrasound-guided erector spinae plane block|PROCEDURE: ultrasound-guided rhomboid intercostal block combined with sub-serratus plane block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, Pharmacodynamic and Pharmacokinetic Effects of Single and Multiple-Doses of ATF936 and AXT914 Administered Orally in Healthy Subjects.
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: ATF936|DRUG: AXT914
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pulmonary Artery Denervation in Patients With Atrial Fibrillation and Group 2 of Pulmonary Hypertension
Status: RECRUITING
Conditions: Atrial Fibrillation|Pulmonary Hypertension
Interventions: PROCEDURE: Pulmonary vein isolation|PROCEDURE: Sham pulmonary artery denervation|PROCEDURE: Pulmonary artery denervation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intravenous Versus Oral Administration of Prednisolone in Exacerbations of Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Intravenous prednisolone|DRUG: Oral prednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: AZD2171 in Treating Patients With Recurrent or Stage IV Melanoma
Status: COMPLETED
Conditions: Acral Lentiginous Malignant Melanoma|Ciliary Body and Choroid Melanoma, Medium/Large Size|Ciliary Body and Choroid Melanoma, Small Size|Extraocular Extension Melanoma|Intraocular Melanoma|Iris Melanoma|Lentigo Maligna Malignant Melanoma|Recurrent Melanoma|Stage, Intraocular Melanoma|Stage IV Melanoma|Superficial Spreading Malignant Melanoma
Interventions: DRUG: cediranib maleate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT