pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Trial of ZD6474, Paclitaxel, Carboplatin, 5-Fluorouracil, and Radiation Therapy Followed by Surgery
Status: COMPLETED
Conditions: Cancer of the Esophagus|Adenocarcinoma of the Gastroesophageal Junction|Cancer of the Stomach
Interventions: DRUG: Vandetanib|DRUG: 5 Fluorouracil (FU)|DRUG: Carboplatin|DRUG: Paclitaxel|RADIATION: External Beam Radiation Therapy (RT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Atrial Fibrillation and By-pass Surgery
Status: UNKNOWN
Conditions: Patients With Coronary Artery Disease Scheduled for by Pass Surgery
Interventions: DRUG: Amiodarone tab 200 mg x 3|DRUG: rosuvastatin 20 mg tab x1|DRUG: beta blockers Bisoprolol in adjusted dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Videolaryngoscopy vs Direct Laryngoscopy for Double Lumen Tube Lumen Tube Placement - A Multicentre Randomized-controlled Trial (VOLCANO Study)
Status: NOT_YET_RECRUITING
Conditions: One Lung Ventilation|Intubation Complication
Interventions: DEVICE: Mc Grath Videolaryngoscope
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Evaluation of New Diagnostic and Treatment Algorithm for Obstructive Sleep Apnea
Status: COMPLETED
Conditions: Sleep Apnea
Interventions: DEVICE: home sleep study|DEVICE: home CPAP titration (Autoset)|DEVICE: CPAP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study of Rivaroxaban Use and Potential Adverse Outcomes in Routine Clinical Practice (Germany)
Status: COMPLETED
Conditions: Venous Thrombosis|Pulmonary Embolism|Atrial Fibrillation|Acute Coronary Syndrome
Interventions: DRUG: Rivaroxaban (Xarelto, Bay59-7939)|DRUG: Standard of care
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: CBCT for Parents of Children With Autism
Status: COMPLETED
Conditions: Stress
Interventions: BEHAVIORAL: Cognitive Based Compassion Training Session: Developing Attention and Stability of Mind|BEHAVIORAL: Cognitive Based Compassion Training Session: Cultivating Insight into the Nature of Mental Experience|BEHAVIORAL: Cognitive Based Compassion Training Session: Self-compassion|BEHAVIORAL: Cognitive Based Compassion Training Session: Cultivating Equanimity|BEHAVIORAL: Cognitive Based Compassion Training Session: Developing Appreciation and Gratitude for Others|BEHAVIORAL: Cognitive Based Compassion Training Session: Developing Affection and Empathy|BEHAVIORAL: Cognitive Based Compassion Training Session: Realizing Wishing and Aspiring Compassion|BEHAVIORAL: Cognitive Based Compassion Training Session: Realizing Active Compassion|BEHAVIORAL: Meditation Session
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Functional Trunk Training in Ataxia Patients
Status: COMPLETED
Conditions: Ataxia, Spinocerebellar|Ataxias, Hereditary
Interventions: OTHER: Functional training|OTHER: Routine training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intra-Operative Electron Boost and Hypofractionated Whole-Breast Irradiation During Breast-conserving Treatment (BCT)
Status: COMPLETED
Conditions: Local Neoplasm Recurrence|Toxicity
Interventions: RADIATION: HIOB
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose-Escalated Hypofractionated Adaptive Radiotherapy for Head and Neck Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Head and Neck Neoplasm
Interventions: RADIATION: 50 Gy Radiation Therapy|RADIATION: 55 Gy Radiation Therapy|RADIATION: 60 Gy Radiation Therapy|DRUG: Atezolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Thrombolysis Treated With TNK-tPA in Acute Ischemic Stroke Patients （3T Stroke-Ⅲ）
Status: RECRUITING
Conditions: Acute Ischemic Stroke
Interventions: DRUG: Alteplase|DRUG: Tenecteplase
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Mesenchymal Stem Cells for Stimulate the Union in Treatment of Non-united Tibial and Femoral Fractures in Shahid Kamyab Hospital
Status: COMPLETED
Conditions: Nonunion Fracture
Interventions: OTHER: injection the mesenchymal stem cell in non union site
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study With ABBV-155 Alone and in Combination With Taxane Therapy in Adults With Relapsed and/or Refractory Solid Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Solid Tumors
Interventions: DRUG: ABBV-155|DRUG: Paclitaxel|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Fixed-dose Combination of Irbesartan/Atorvastatin in Type 2 Diabetic Patients Diagnosed With Hyperlipidemia and Hypertension
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Irbesartan/atorvastatin fixed dose combination|DRUG: Irbesartan SR47436|DRUG: Atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial Comparing Efficacy of HM3 Versus F2 Lithotripters for Stone Fragmentation
Status: TERMINATED
Conditions: Urolithiasis
Interventions: PROCEDURE: Extracorporeal Shock Wave Lithotripsy (ESWL)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics Following Intravenous Administration of IRX-010 in Healthy Participants
Status: RECRUITING
Conditions: Healthy Participants
Interventions: DRUG: IRX-010|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: International Safety and Efficacy Study of Aztreonam for Inhalation Solution (AZLI) in Cystic Fibrosis Patients With P. Aeruginosa
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: AZLI 75 mg three times a day (TID)|DRUG: Placebo three times a day (TID)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sulforaphane for the Treatment of Young Men With Autism Spectrum Disorder
Status: COMPLETED
Conditions: Autism Spectrum Disorder|Autistic Disorder|Neurodevelopmental Disorder|Childhood Developmental Disorders, Pervasive
Interventions: DRUG: Sulforaphane|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess Safety and Preliminary Efficacy of LP-108 Combined With Azacitidine In Subjects With AML, MDS, CMML
Status: RECRUITING
Conditions: Acute Myeloid Leukemia|Myelodysplastic Syndromes|Chronic Myelomonocytic Leukemia
Interventions: DRUG: LP-108|DRUG: Azacitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Safety and Tolerability of Romosozumab in the Treatment of Japanese Women With Postmenopausal Osteoporosis
Status: COMPLETED
Conditions: Postmenopausal Osteoporosis (PMO)
Interventions: DRUG: Romosozumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Methylphenidate Versus Placebo on State Anxiety in Children With Attention Deficit Hyperactivity Disorder.
Status: UNKNOWN
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: DRUG: Methylphenidate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Assessing People's Hospital Outpatient Appointment Preferences in the United Kingdom
Status: COMPLETED
Conditions: Hospital Outpatient Clinics|Chronic Disease
Interventions: BEHAVIORAL: Video Default|BEHAVIORAL: In-Person Default|BEHAVIORAL: Active Choice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Efficacy of Inhaling Bronchodilator Medications in Chronic Obstructive Pulmonary Disease
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: arformoterol|DRUG: salmeterol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bilateral Erector Spinae Plane Block for Postoperative Chronic Pain After Open Heart Surgery
Status: RECRUITING
Conditions: Chronic Pain|Cardiac Surgery|Post Operative Pain
Interventions: PROCEDURE: Bilateral ultrasound guided erector spinae plane block|DRUG: morphine PCA|OTHER: Control group|DRUG: morphine PCA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Use of Midazolam as Adjuvant to Bupivacaine Intrathecal Anesthesia for Children Undergoing Lower Abdominal Surgeries.
Status: COMPLETED
Conditions: Analgesia|Children, Only|Bupivacaine|Midazolam
Interventions: DRUG: intrathecal bupivacaine|DRUG: midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Study to Evaluate Drug-Drug Interactions of Obicetrapib Tablets and Ezetimibe Tablets in Healthy Adult Subjects
Status: NOT_YET_RECRUITING
Conditions: Healthy Volunteers
Interventions: DRUG: Obicetrapib 10mg|DRUG: Ezetimibe 10mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: School-based Behavioural Intervention to Face Obesity and Promote Cardiovascular Health Among Spanish Adolescents
Status: ACTIVE_NOT_RECRUITING
Conditions: Obesity|Cardiovascular Health|Diabetes Mellitus
Interventions: BEHAVIORAL: Long-term educational program|BEHAVIORAL: Short-term educational program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Phase 3 Study of Walter Reed (WR) 279,396 and Paromomycin Alone for the Treatment of Cutaneous Leishmaniasis in Panama
Status: COMPLETED
Conditions: Cutaneous Leishmaniasis
Interventions: DRUG: WR 279,396|DRUG: Paromomycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Truvada Plus Raltegravir for Nonoccupational Post-exposure Prophylaxis (nPEP)
Status: COMPLETED
Conditions: HIV
Interventions: DRUG: Truvada|DRUG: Raltegravir
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Revascularization of Stenosed Vessels Using Optimized Treatment of Rejuveinix for Reversing Endothelial Dysfunction
Status: UNKNOWN
Conditions: Critical Limb Ischemia|Peripheral Arterial Disease
Interventions: DRUG: Rejuveinix Low Dose|DRUG: Rejuveinix High Dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Phase Ⅲ Study of Extended-Release Carvedilol Sulfate for the Treatment of Hypertension
Status: UNKNOWN
Conditions: Hypertension
Interventions: DRUG: Extended-Release Carvedilol Sulfate|DRUG: Sustained-release Metoprolol Succinate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Duration of Cardiac Antimicrobial Prophylaxis Outcomes Study
Status: RECRUITING
Conditions: Surgical Site Infection
Interventions: DRUG: Cefazolin|DRUG: Water for injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Fractionated Busulfan Conditioning Regimen for Allo-HSCT in Non-remission Myeloid Malignancies
Status: RECRUITING
Conditions: Myeloid Malignancies
Interventions: DRUG: fractionated busulfan-based conditioning regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Randomized Study of Stereotactic Radiosurgery Plus Fractionated Whole-Brain Radiotherapy Vs Fractionated Whole-Brain Radiotherapy Alone for Multiple Primary or Metastatic Brain Tumors
Status: UNKNOWN
Conditions: Brain Neoplasms
Interventions: PROCEDURE: irradiation|PROCEDURE: radiosurgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of High-Flow Nasal Cannula Versus Noninvasive Ventilation for Pulmonary Arterial Hypertension-Associated Acute Respiratory Failure
Status: ACTIVE_NOT_RECRUITING
Conditions: Pulmonary Arterial Hypertension|Acute Respiratory Failure|High-flow Nasal Cannula|Noninvasive Ventilation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety Study of Rimegepant for the Acute Treatment of Migraine in Japanese Subjects (Japan Only)
Status: COMPLETED
Conditions: Migraine
Interventions: DRUG: Rimegepant 25 MG|DRUG: Rimegepant 75 MG|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Adding TENS to Conventional Physical Therapy Exercise on Pain Relief Among Patients With Pudendal Neuralgia.
Status: COMPLETED
Conditions: Pudendal Neuralgia
Interventions: DEVICE: Trans-cutaneous Electrical Nerve Stimulation|PROCEDURE: Conventional physical therapy exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: School-based Support for Pre-school Aged Children With Developmental Disabilities and Delays
Status: RECRUITING
Conditions: Developmental Delay
Interventions: BEHAVIORAL: Preschool and Me
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study of LBH589 for Patients With Low or Intermediate-1 Risk Myelodysplastic Syndrome (MDS)
Status: TERMINATED
Conditions: Myelodysplastic Syndrome
Interventions: DRUG: LBH589
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Root Caries in an Older Irish Population.
Status: UNKNOWN
Conditions: Active Root Caries|Over Sixty-five Years of Age|>=Two Carious Root Surfaces Per Patient
Interventions: DEVICE: Calcium silicate cement|DEVICE: Glass Ionomer Cement|DEVICE: Resin Modified Glass Ionomer Cement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Examination of Ocular Surface Effects With Administration of Travatan Z and XALATAN
Status: COMPLETED
Conditions: Open-angle Glaucoma|Ocular Hypertension
Interventions: DRUG: Travoprost ophthalmic solution 0.004% with SofZia® preservative system (TRAVATAN Z®)|DRUG: Latanoprost ophthalmic solution 0.005% (XALATAN®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial Assessing Peri-procedure Chemoprophylaxis During Transrectal Prostate Needle Biopsy
Status: COMPLETED
Conditions: Benign Prostate Hyperplasia
Interventions: DRUG: ciprofloxacin|DRUG: ciprofloxacin and gentamycine|DRUG: culture based chemoprophylaxis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Study to Assess the Cosmetic Changes in the Facial Skin After Use of a Topical Retinoid Product in Participants With Moderate to Severe Photodamage
Status: COMPLETED
Conditions: Skin Care
Interventions: OTHER: Retinol Complex 0.5|OTHER: Facial cleanser|OTHER: Moisturizing lotion|OTHER: Sunscreen|DEVICE: Skin Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of a New Chemotherapy Agent in Combination With Cisplatin to Treat Small Cell Lung Cancer
Status: COMPLETED
Conditions: Carcinoma, Small Cell
Interventions: DRUG: Sagopilone (BAY86-5302, ZK 219477)|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Better Leukemia Diagnostics Through AI (BELUGA)
Status: RECRUITING
Conditions: Hematologic Malignancy|Leukemia|Minimal Residual Disease|Lymphoma|Blood Cancer
Interventions: DIAGNOSTIC_TEST: Automated AI-Guided Diagnosis of Hematological Malignancies
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of FX006 for the Treatment of Pain in Patients With Osteoarthritis of the Knee
Status: COMPLETED
Conditions: Osteoarthritis of the Knee
Interventions: DRUG: FX006|DRUG: Placebo|DRUG: TCA IR 40
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Corneal Collagen Cross-linking Following LASIK for Treatment of Hyperopia and Hyperopic Astigmatism
Status: TERMINATED
Conditions: Hyperopia|Hyperopic Astigmatism
Interventions: DRUG: riboflavin ophthalmic solution, 0% dextran|DEVICE: UVA Irradiation (30 mW/cm2 for 2 minutes continuous UVA)|DEVICE: UVA Irradiation (30 mW/cm2 for 3 minutes pulsed UVA with an on/off cycle of 2 seconds UVA on/1 second UVA off)|PROCEDURE: Laser-assisted in situ keratomileusis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Adenovirus Type 35 Based Circumsporozoite Malaria Vaccine in Burkina Faso
Status: COMPLETED
Conditions: Malaria
Interventions: BIOLOGICAL: Ad35.CS.01 Circumsporozoite Malaria Vaccine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: TA-65 and Aging Associated Microvascular Dysfunction
Status: NOT_YET_RECRUITING
Conditions: Telomere Shortening|Aging|Vascular Diseases
Interventions: DIETARY_SUPPLEMENT: TA-65|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy of Phonophoresis With Topical Glyceryl Trinitrate in Treatment of Achilles Tendinopathy
Status: COMPLETED
Conditions: Non Insertional Achilles Tendinopathy
Interventions: OTHER: topical glyceryl trinitrate gel|OTHER: Eccentric exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: US 10 mL Biologic Lung Volume Reduction (BLVR) Phase 1 Emphysema Study
Status: COMPLETED
Conditions: Pulmonary Emphysema
Interventions: DRUG: BLVR System
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Toripalimab Combined With Anlotinib for Patients With Advanced, Relapsed, or Refractory Gastric, or Esophagogastric Junction Cancer (EGJC)
Status: UNKNOWN
Conditions: Gastric or Gastro-oesophageal Junction Carcinoma|Advanced, Relapsed Gastric or Gastro-oesophageal Junction Carcinoma|Second-line Therapy
Interventions: GENETIC: FGFR2
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Isotretinoin Plus Dexamethasone in Treating Patients With Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma and Plasma Cell Neoplasm
Interventions: DRUG: dexamethasone|DRUG: isotretinoin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of Maraviroc/Raltegravir for Naive HIV-1 Patients
Status: UNKNOWN
Conditions: HIV
Interventions: DRUG: MVC/RAL/FTC/TDF followed by Maraviroc/Raltegravir
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of Two Daily Disposable Silicone Hydrogel Contact Lenses
Status: COMPLETED
Conditions: Myopia
Interventions: DEVICE: Delefilcon A contact lenses (DAILIES TOTAL1®)|DEVICE: Narafilcon B contact lenses (1-DAY ACUVUE® TruEye®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Influence of Morphine or Ketamine or Saline Applied During In-hospital Cardiopulmonary Resuscitation on Early Survival
Status: NOT_YET_RECRUITING
Conditions: Cardiac Arrest
Interventions: DRUG: Morphine|DRUG: Ketamine Injectable Solution|DRUG: Saline 0.9%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Naloxegol on Gastric, Small Bowel, and Colonic Transit in Healthy Subjects
Status: COMPLETED
Conditions: Constipation Drug Induced
Interventions: DRUG: Naloxegol|DRUG: Codeine|DRUG: codeine placebo|DRUG: naloxegol placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of Resveratrol in Older Adults With Impaired Glucose Tolerance
Status: COMPLETED
Conditions: Impaired Glucose Tolerance
Interventions: DIETARY_SUPPLEMENT: resveratrol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Computed Tomography (CT) and Lung Function Data Collection for Computational Fluid Dynamics (CFD) in Chronic Obstructive Pulmonary Disease (COPD) Patients
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: PROCEDURE: Computed Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Evaluate the Efficacy and Safety of Apremilast (CC-10004) in the Treatment of Behçet Disease
Status: COMPLETED
Conditions: Behcet Syndrome
Interventions: DRUG: Apremilast (CC-10004)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vitamin D and Omega-3 Trial (VITAL)
Status: ACTIVE_NOT_RECRUITING
Conditions: Cancer|Cardiovascular Disease
Interventions: DIETARY_SUPPLEMENT: vitamin D3|DRUG: omega-3 fatty acids (fish oil)|DIETARY_SUPPLEMENT: Vitamin D3 placebo|DIETARY_SUPPLEMENT: Fish oil placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of Artificial Disc Implants in Cervical Disc Arthroplasty
Status: RECRUITING
Conditions: Cervical Spondylosis With Myelopathy|Cervical Radiculopathy|Cervical Disc Herniation|Degenerative Disc Disease
Interventions: PROCEDURE: Cervical arthroplasty|DEVICE: Semi-Constrained Nuvasive Simplify|DEVICE: Unconstrained Biomet Zimmer Mobi-C
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Attention Bias Modification Treatment (ABMT) for Anxiety Disorders in Youth Who do Not Respond to CBT
Status: UNKNOWN
Conditions: Anxiety Disorders
Interventions: BEHAVIORAL: Attention bias modification treatment (ABMT)|BEHAVIORAL: Attention Control Condition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Reversal of Epidermal Phenotype in Severe Atopic Dermatitis With Cyclosporine Therapy
Status: COMPLETED
Conditions: Atopic Dermatitis|Eczema
Interventions: DRUG: Cyclosporine A
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Guided Bone Regeneration Using Fixed vs Non-Fixed Resorbable Collagen Membranes
Status: RECRUITING
Conditions: Bone Resorption
Interventions: PROCEDURE: Horizontal GBR with the use of non-resorbable pins for the stabilization of the collagen membrane|PROCEDURE: Horizontal GBR without the use of non-resorbable pins for the stabilization of the collagen membrane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Concerta and Strattera on the Executive Function in Attention Deficit Hyperactivity Disorder (ADHD) Children
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: DRUG: OROS MPH|DRUG: Atomoxetine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 3 Trial of Blinatumomab vs Standard Chemotherapy in Pediatric Subjects With HIgh-Risk (HR) First Relapse B-precursor Acute Lymphoblastic Leukemia (ALL)
Status: COMPLETED
Conditions: Leukemia, Acute Lymphoblastic
Interventions: DRUG: Blinatumomab|DRUG: Dexamethasone|DRUG: Vincrisitne|DRUG: Daunorubicin|DRUG: Methotrexate|DRUG: Ifosfamide|DRUG: PEG-asparaginase|DRUG: Erwinia-asparaginase
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of N-butyl-cyanoacrylate and Micro Parti-cles Effect in Inducing Liver Hypertrophy After PVE
Status: COMPLETED
Conditions: Portal Vein Embolization, Liver, Hypertrophy
Interventions: PROCEDURE: Portal vein embolization
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pai.ACT Programme for Parents of Children With Special Healthcare Needs - Phase I
Status: RECRUITING
Conditions: Neurodevelopmental Disorders|Attention Deficit Hyperactivity Disorder|Autism Spectrum Disorder|Development Delay|Chronic Disease
Interventions: BEHAVIORAL: Focused Acceptance and Commitment Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combined aPproach to Treatment Using Ranibizumab and Efalizumab for Diabetic Macular Edema Study: The CAPTURE DME Study
Status: WITHDRAWN
Conditions: Diabetic Macular Edema
Interventions: DRUG: Efalizumab|DRUG: Ranibizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Nutritional Supplementation in Altering Ecchymosis, Erythema and Health Outcomes Associated With Aesthetic Procedures
Status: COMPLETED
Conditions: Ecchymosis and Erythema Commonly Associated With Soft Tissue Filler Injections
Interventions: DIETARY_SUPPLEMENT: Multizyme Cellular Vitality Cyruta Plus SHEP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Combination Therapy With LdT Plus Adefovir Versus Adefovir Alone
Status: TERMINATED
Conditions: Hepatitis B
Interventions: DRUG: telbivudine|DRUG: adefovir dipivoxil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anatomic Versus Physiologic Guidance for Complete Revascularization With DES Eluting in Patients With CAD
Status: RECRUITING
Conditions: Coronary Disease
Interventions: PROCEDURE: Percutaneous Coronary Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Study to Assess the Clinical Efficacy and Safety of Intravitreal Aflibercept Injection (IAI;EYLEA®;BAY86-5321) in Patients With Branch Retinal Vein Occlusion (BRVO)
Status: COMPLETED
Conditions: Branch Retinal Vein Occlusion
Interventions: PROCEDURE: Macular Laser Photocoagulation|DRUG: Intravitreal Aflibercept Injection (IAI;EYLEA®;BAY86-5321)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: AlloMend Acellular Dermal Matrix Allograft in Pre-Pectoral Breast Reconstruction
Status: RECRUITING
Conditions: Pre-Pectoral Breast Reconstruction Following Single or Double Mastectomy
Interventions: OTHER: AlloMend® Acellular Dermal Matrix allograft
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Gabapentin for Prophylaxis Intrathecal Morphine-Induced Pruritus
Status: COMPLETED
Conditions: Pruritus
Interventions: DRUG: Gabapentin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: EBUS-TBNA vs Flex 19G EBUS-TBNA
Status: UNKNOWN
Conditions: Lymphadenopathy|Lung Cancer|Sarcoidosis|Lymphoma
Interventions: DEVICE: 21G EBUS-TBNA needle|DEVICE: Flexible 19G EBUS-TBNA needle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparative Effects of Conventional Physical Therapy, Kinesio Taping and ESWT in Upper Trapezius MPS.
Status: COMPLETED
Conditions: Trapezius Muscle Strain
Interventions: DEVICE: Extracorporeal Shock Wave Therapy|OTHER: Kinesiotaping|OTHER: Conventional Physical Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Observational Study to Evaluate the Safety and Efficacy of Humacyte's HAV for Arterial Replacement or Reconstruction in Ukrainian Patients With Life or Limb-threatening Vascular Trauma
Status: COMPLETED
Conditions: Trauma|Trauma Injury|Trauma, Multiple|Trauma Blunt
Interventions: BIOLOGICAL: HAV implantation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Dronabinol in Opioid Maintained Patients
Status: RECRUITING
Conditions: Pain
Interventions: DRUG: Dronabinol|DRUG: Dronabinol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Bovine Intestinal Alkaline Phosphatase for the Treatment of Patients With Sepsis
Status: COMPLETED
Conditions: Sepsis|Multiple Organ Dysfunction Syndrome
Interventions: DRUG: Alkaline Phosphatase|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: ARTEMIS: Ravulizumab to Protect Patients With CKD From CSA-AKI and MAKE
Status: RECRUITING
Conditions: Chronic Kidney Disease|CKD|Cardiac Disease|Cardiopulmonary Bypass
Interventions: DRUG: Placebo|DRUG: Ravulizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Examining Blood and Tissue Samples to Identify Diagnostic Markers in Patients With Metastatic Cancer Undergoing Tumor Removal
Status: RECRUITING
Conditions: Hematopoietic and Lymphoid System Neoplasm|Metastatic Malignant Solid Neoplasm
Interventions: PROCEDURE: Biopsy Specimen|PROCEDURE: Biospecimen Collection|PROCEDURE: Biospecimen Collection|OTHER: Medical Chart Review
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Swiss Secondary Prevention and Rehabilitation Registry
Status: RECRUITING
Conditions: Cardiovascular Diseases (CVD)
Interventions: OTHER: Data collection at Baseline, 3 months after baseline (BL), 1-year follow-up, Telephone follow-up and questionnaire 3 years and 5 years after BL
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Dignity Therapy Applied to Cancer Patients
Status: NOT_YET_RECRUITING
Conditions: Cancer|Dignity
Interventions: BEHAVIORAL: Dignity therapy|OTHER: standardize care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: First Line Sintilimab Combined With Anlotinib and Platinum Doublet Chemotherapy in Malignant Pleural Mesothelioma
Status: NOT_YET_RECRUITING
Conditions: Mesothelioma, Malignant|Mesothelioma, Malignant Pleural|Mesothelioma Malignant Advanced
Interventions: DRUG: Sintilimab+Anlotinib+Pemetrexed+Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Carfilzomib for Multiple Myeloma Patients Who Are Relapsed/Refractory to Bortezomib-containing Treatments
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Group A: Carfilzomib & Non-IMiD Regimen|DRUG: Group B: Carfilzomib & IMiD containing regimen.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics Study of TNO155 in Participants With Mild, Moderate, or Severe Renal Impairment Compared to Matched Healthy Participants
Status: WITHDRAWN
Conditions: Renal Impairment
Interventions: DRUG: TNO155
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation of the Effectiveness and Safety of AI-Robotics
Status: COMPLETED
Conditions: Lower Extremity Motor Dysfunction, Spinal Cord Injury
Interventions: DEVICE: AiLegs, AiWalker and HKAFO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tapinarof for the Treatment of Atopic Dermatitis in Children and Adults (DMVT-505-3102)
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: tapinarof cream, 1%|DRUG: vehicle cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety and Efficacy of PEER Interactive Versus Treatment as Usual in Subjects With a Primary Diagnosis of Depression
Status: SUSPENDED
Conditions: Depressive Disorder
Interventions: DEVICE: PEER Interactive Report
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Testing an Active Form of Tamoxifen (4-hydroxytamoxifen) Delivered Through the Breast Skin to Control Ductal Carcinoma in Situ (DCIS) of the Breast
Status: RECRUITING
Conditions: Ductal Breast Carcinoma In Situ|Estrogen Receptor Positive
Interventions: DRUG: Afimoxifene|OTHER: Laboratory Biomarker Analysis|OTHER: Placebo|OTHER: Placebo|DRUG: Tamoxifen Citrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Dyslipidemia Study Investigating The Increase In "Good Cholesterol"
Status: COMPLETED
Conditions: Dyslipidaemias
Interventions: DRUG: GW590735|DRUG: fenofibrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Cellular Stromal Vascular Fraction in Multiple Sclerosis,Autoimmune, Inflammatory, Neurologic Conditions
Status: WITHDRAWN
Conditions: Multiple Sclerosis|Autoimmune
Interventions: PROCEDURE: Microcannula Harvest Adipose|DEVICE: Centricyte 1000|PROCEDURE: Sterile Normal Saline IV deployment AD-cSVF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Circulating Tumor Cells as Tools for Therapy Response in Nab-paclitaxel Treated Metastatic Pancreatic Cancer Patients
Status: COMPLETED
Conditions: Metastatic Pancreatic Cancer
Interventions: DRUG: Nab paclitaxel / gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Proof of Concept Study; The Effect of an Encapsulated Nutrient Mixture on Ileal Brake Activation
Status: COMPLETED
Conditions: Body Weight Decreased
Interventions: OTHER: Encapsulated nutrients|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Study of the Efficacy of Daylight Activated Photodynamic Therapy in the Treatment of Cutaneous Leishmaniasis
Status: UNKNOWN
Conditions: Cutaneous Leishmaniasis
Interventions: PROCEDURE: Photodynamic therapy|PROCEDURE: Cryotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Effect of Tezepelumab on the Immune Response to Influenza Vaccination in Participants With Asthma
Status: COMPLETED
Conditions: Moderate to Severe Asthma
Interventions: DRUG: Tezepelumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of the DTS-G2 System in Patients With Axillary Hyperhidrosis
Status: COMPLETED
Conditions: Primary Focal Hyperhidrosis, Axilla
Interventions: DEVICE: DTS-G2 System|DEVICE: DTS System (Sham treatment)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study Evaluating Safety of ExOlin® in Patients With Poorly Controlled Type 1 Diabetes
Status: RECRUITING
Conditions: Type 1 Diabetes|Type 1 Diabetes Mellitus With Hypoglycemia
Interventions: DEVICE: ExOlin®|DRUG: Insulin aspart
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase Ib/II Trial of coPANlisib in Combination With Trastuzumab in HER2-positive Breast Cancer. (Panther Study)
Status: COMPLETED
Conditions: HER2 Positive Breast Cancer
Interventions: DRUG: Copanlisib|DRUG: Trastuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Attentional Bias Modification in Fibromyalgia Patients (ABM)
Status: COMPLETED
Conditions: Fibromyalgia
Interventions: BEHAVIORAL: ABM|BEHAVIORAL: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect of Mobile Health-Education Application on Healthy Lifestyle Behaviors in Patients Planned for Bariatric Surgery
Status: SUSPENDED
Conditions: Nursing Caries|Bariatric Surgery Candidate|Mobile Education
Interventions: OTHER: mobile education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Trial to Compare the Routes of Administration of an Investigational, Personalized, Therapeutic Cancer Vaccine Oncophage (HSPPC-96) in Patients With Metastatic Renal Cell Carcinoma
Status: TERMINATED
Conditions: Renal Cell Carcinoma
Interventions: BIOLOGICAL: autologous human tumor-derived HSPPC-96
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pre-diltiazem, Calcium Versus Placebo for Atrial Fibrillation With Rapid Ventricular Response
Status: NOT_YET_RECRUITING
Conditions: Atrial Fibrillation With Rapid Ventricular Response|Hypotension
Interventions: DRUG: Placebo|DRUG: Calcium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Comparison of Hemodynamic Effects Between Remimazolam-remifentanil and Propofol-remifentanil in Patients Undergoing Laparoscopic Cholecystectomy
Status: COMPLETED
Conditions: Acute Cholecystitis
Interventions: DRUG: propofol group|DRUG: remimazolam group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Methylprednisolone Given by 24-Hour or 48-Hour Infusion Versus Tirilazad for Acute Spinal Cord Injury
Status: COMPLETED
Conditions: Spinal Cord Injury
Interventions: DRUG: methylprednisolone|DRUG: tirilazad
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Gla-300 and IDeg-100 in Insulin-Naïve People With Type 2 Diabetes Mellitus and Renal Impairment
Status: TERMINATED
Conditions: Type 2 Diabetes Mellitus|Renal Impairment
Interventions: DRUG: Insulin glargine 300 U/mL|DRUG: Insulin degludec 100 U/mL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Safety and Dose-range Study of Metacavir Enteric-coated Capsules in Patients With Chronic Hepatitis B
Status: UNKNOWN
Conditions: Chronic Hepatitis B
Interventions: DRUG: Metacavir Enteric-coated Capsules 80mg|DRUG: Metacavir Enteric-coated Capsules 160mg|DRUG: Metacavir Enteric-coated Capsules 320mg|DRUG: Metacavir Enteric-coated Capsules Placebo 240mg|DRUG: Metacavir Enteric-coated Capsules Placebo 160mg|DRUG: Metacavir Enteric-coated Capsules Placebo 320mg|DRUG: Adefovir Dipivoxil Capsule10mg|DRUG: Adefovir Dipivoxil Capsule Placebo 10mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Pre- or Post-operative HYPOfractionated Radiation Therapy in Aged (≥ 70 Years Old) or "Fragile" (≥ 65 Years) Patients With Limb or Trunk Soft Tissue SARComa.
Status: RECRUITING
Conditions: Soft Tissue Sarcoma
Interventions: PROCEDURE: Patients will receive the hypofractionated radiation therapy (30 Gy in 5 fractions) prior to surgery.|PROCEDURE: Patient will undergo surgery before receive the adjuvant hypofractionated radiation therapy (40 Gy in 15 fractions).
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Compare the Efficacy and Safety of Using oXiris and M100 During CRRT
Status: RECRUITING
Conditions: AKI - Acute Kidney Injury|Pneumonia
Interventions: DEVICE: oXiris filter|DEVICE: M100 filter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Self-Help Metacognitive Therapy for Cardiac Rehabilitation Patients (PATHWAY WS3)
Status: TERMINATED
Conditions: Depression|Anxiety|Cardiac Rehabilitation|Psychological Distress
Interventions: OTHER: Home-based Metacognitive Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acute Atrial Fibrillation and Flutter Treated Electively
Status: RECRUITING
Conditions: Atrial Fibrillation|Atrial Flutter
Interventions: OTHER: Acute cardioversion|OTHER: Delayed cardioversion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sequential Treatment With CD20/CD22/CD10-CART After CD19-CART Treatment Base on MRD in Relapsed/Refractory B-ALL
Status: RECRUITING
Conditions: Therapy Related Leukemia
Interventions: BIOLOGICAL: Sequential Treatment With different CART
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of Probiotics in Systemic Sclerosis Associated Gastrointestinal Disease
Status: UNKNOWN
Conditions: Systemic Sclerosis
Interventions: DIETARY_SUPPLEMENT: Vivomixx probiotics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Childhood Adenotonsillectomy Study for Children With OSAS
Status: COMPLETED
Conditions: Obstructive Sleep Apnea|Snoring
Interventions: PROCEDURE: Adenotonsillectomy (AT) - removal of adenoids and tonsils|OTHER: Watchful Waiting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Digital Outreach Intervention for Lung Cancer Screening
Status: ACTIVE_NOT_RECRUITING
Conditions: Lung Cancer
Interventions: OTHER: mPATH-Lung|OTHER: Lung health video
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING