pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Study of the Effectiveness and Safety of Risperidone Versus Placebo in the Treatment of Children With Autistic Disorder and Other Pervasive Developmental Disorders (PDD)
Status: COMPLETED
Conditions: DCild Development Disorders, Pervasive|Autistic Disorder|Developmental Disabilities|Asperger Syndrome|Rett Syndrome
Interventions: DRUG: risperidone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Photodynamic Therapy Using Lutetium Texaphyrin in Treating Patients With Cervical Intraepithelial Neoplasia
Status: TERMINATED
Conditions: Cervical Cancer|Cervical Intraepithelial Neoplasia Grade 2|Cervical Intraepithelial Neoplasia Grade 3
Interventions: DRUG: motexafin lutetium|DRUG: photodynamic therapy|PROCEDURE: loop electrosurgical excision procedure|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Potential for Inhaled Nitric Oxide and Ventilation-Perfusion Mismatch by Electrical Impedance Tomography in the ARDS Patients With Lung Recruitment
Status: ENROLLING_BY_INVITATION
Conditions: Nitric Oxide|Acute Respiratory Distress Syndrome
Interventions: DEVICE: Lung recruitment combined inhaled Nitric oxide|DEVICE: Lung recruitment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study of the Impact of Dairy Fat on Cardiovascular Health.
Status: COMPLETED
Conditions: Metabolic Syndrome
Interventions: OTHER: Cheese diet|OTHER: Butter diet|OTHER: CHO diet|OTHER: MUFA diet|OTHER: PUFA diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Soluble Beta-glucan (SBG) as Treatment for Diabetic Foot Ulcers
Status: COMPLETED
Conditions: Chronic Diabetic Foot Ulcers
Interventions: DRUG: Soluble beta-glucan (SBG)|DRUG: Placebo comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: First-in-Human Single Ascending and Multiple Dose of GLPG0778
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: GLPG0778|DRUG: placebo|DRUG: GLPG0778|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Impact of Low Nicotine Cigarette Messaging on Perceptions and Cigarette Choices
Status: COMPLETED
Conditions: Smoking|Cigarette
Interventions: DRUG: Low Nicotine Content Cigarettes|OTHER: Control message|OTHER: Test message
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Efficacy of FK949E in Bipolar Disorder Patients With Major Depressive Episodes
Status: COMPLETED
Conditions: Bipolar Disorder
Interventions: DRUG: FK949E|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bacille Calmette Guérin Immunisation at Birth and Childhood Morbidity in Danish Children.
Status: COMPLETED
Conditions: Prospective|Single-blind|Clinical|Trial|Intervention
Interventions: BIOLOGICAL: BCG-vaccine (SSI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Stage I/II Nasal NK Cell Lymphoma
Status: TERMINATED
Conditions: Lymphoma
Interventions: RADIATION: Radiation|DRUG: Cyclophosphamide|DRUG: Doxorubicin|DRUG: Vincristine|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Bee Wax Mammary Areolae to Improve Breastfeeding
Status: UNKNOWN
Conditions: Breastfeeding
Interventions: BIOLOGICAL: Bee Wax Mammary Areolae|OTHER: Usual educational care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Negative Pressure Wound Therapy Compared to Traditional Care After Skin Grafting
Status: ACTIVE_NOT_RECRUITING
Conditions: Wound of Skin|Wound Heal|Wound|Wound Open|Wound Breakdown|Skin Wound|Skin Scarring
Interventions: DEVICE: Negative Pressure Wound Therapy|PROCEDURE: Conventional treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Kalogon Pilot Fatigue and Comfort Study
Status: COMPLETED
Conditions: B52 Pilot Fatigue and Comfort
Interventions: DEVICE: Kalogon AF Prototype Smart Cushion|DEVICE: Standard Seat Cushion from Air Force
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Burst Spinal Cord Stimulation for Neuropathic Pain
Status: COMPLETED
Conditions: Neuropathic Pain
Interventions: PROCEDURE: dorsal column stimulator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Long-term Intervention With Weight Loss in Patients With Concomitant Obesity and Knee Osteoarthritis. The LIGHT Study
Status: COMPLETED
Conditions: Osteoarthritis, Knee|Obesity
Interventions: DIETARY_SUPPLEMENT: day formula diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy Evaluation of Dotarem®-Enhanced MRI Compared to Gadovist®/Gadavist®-Enhanced MRI in the Diagnosis of Brain Tumors
Status: COMPLETED
Conditions: Primary Brain Tumor
Interventions: DRUG: Dotarem®|DRUG: Gadovist®/Gadavist®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Multicenter Randomized Controlled Trial Adjuvant Chemotherapy vs Observation in pStage Ib Lung Adenocarcinoma
Status: UNKNOWN
Conditions: Stage Ib Lung Carcinoma
Interventions: DRUG: vinorelbine plus cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Technology-Based Cognitive and Artistic Therapeutic Activities on the Mental Status of Children With Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Children Followed up With Cancer Diagnosis
Interventions: BEHAVIORAL: Technology-based cognitive and artistic therapeutic activities
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Interactive Web-Based Tool for Pelvic Organ Prolapse: Impact on Patient Understanding and Provider Counseling
Status: COMPLETED
Conditions: Pelvic Organ Prolapse
Interventions: OTHER: "Usual practice" counseling|OTHER: Standard "usual practice" clinical counseling with the pelvic organ prolapse web-based tool (iPad).
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Regional Anesthesia and Lung Cancer Recurrence
Status: TERMINATED
Conditions: Lung Cancer
Interventions: OTHER: General-epidural anesthesia|OTHER: Balanced general anesthesia and postoperative opioids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Automatic Self Transcending Meditation (ASTM) for Patients With Severe Age Related Macular Degeneration (AMD)
Status: UNKNOWN
Conditions: Age-related Macular Degeneration|Low Vision
Interventions: OTHER: Automatic Self Transcending Meditation|OTHER: Treatment as Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety Study of IL-7 in Recipients of a Hemopoietic Stem Cell Transplant Peripheral Blood Stem Cell Transplant
Status: COMPLETED
Conditions: AML|CML|MDS
Interventions: DRUG: CYT107 - Recombinant glycosylated human interleukin 7.|DRUG: rhIL-7 (CYT107)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of High Risk Adult Acute Lymphoblastic Leukemia
Status: COMPLETED
Conditions: Acute Lymphoblastic Leukemia
Interventions: DRUG: Vincristine|DRUG: Daunorubicin|DRUG: Prednisone|DRUG: Mitoxantrone|DRUG: Cytosine Arabinoside|DRUG: Dexamethasone|DRUG: Methotrexate (MTX)|DRUG: Cytarabine|DRUG: ASP|DRUG: Mercaptopurine|DRUG: Teniposide|DRUG: Hydrocortisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of Intra-articular Hyaluronic Acid in the Knee Osteoarthritis
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: DEVICE: Sinovial® (syringe containing sodium hyaluronate solution)|DEVICE: Synvisc® ( syringe containing Hylan G-F 20 solution)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of XP12B in Women With Menorrhagia
Status: COMPLETED
Conditions: Menorrhagia|Heavy Menstrual Bleeding
Interventions: DRUG: Tranexamic acid tablets|DRUG: Placebo tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Stereotactic Body Radiotherapy Boost After Palliative Radiotherapy for Spinal Cord Compression
Status: UNKNOWN
Conditions: Spinal Cord Compression|Cauda Equina Syndrome|Stereotactic Body Radiotherapy
Interventions: RADIATION: 3D CRT plus SBRT boost
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Bictegravir/Emtricitabine/Tenofovir Alafenamide Versus Dolutegravir + Emtricitabine/Tenofovir Disoproxil Fumarate in Treatment Naive, HIV-1 and Hepatitis B Co-Infected Adults
Status: COMPLETED
Conditions: HIV-1/HBV Co-Infection
Interventions: DRUG: B/F/TAF|DRUG: Placebo to match DTG|DRUG: Placebo to match F/TDF|DRUG: DTG|DRUG: F/TDF|DRUG: Placebo to match B/F/TAF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Description of the Interdigitation Retinal Area by SD-OCT: An Exploratory Study
Status: COMPLETED
Conditions: Tomography, Optical Coherence|Retina
Interventions: DEVICE: Spectral Domain Optical Coherence Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: WeChat-based Intervention for Internet Addiction
Status: ACTIVE_NOT_RECRUITING
Conditions: Internet Addiction
Interventions: BEHAVIORAL: Self-initiated learning|BEHAVIORAL: Personalized and interactive behavioural support|BEHAVIORAL: General health information
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Visual and Refractive Results and Rotational Stability of the TECNIS® Eyhance Toric II 1-piece Posterior Chamber Lens in Patients With Astigmatism Undergoing Cataract Surgery
Status: TERMINATED
Conditions: Cataract|Astigmatism
Interventions: PROCEDURE: Images of the operated eye (s)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Sonodynamic Therapy Using SONALA-001 and Exablate 4000 Type 2.0 in Subjects With Recurrent GBM
Status: TERMINATED
Conditions: Recurrent GBM
Interventions: COMBINATION_PRODUCT: SONALA-001 (ALA) and MR-Guided Focused Ultrasound device (MRgFUS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Oral Nutritional Supplementation in Children at Risk of Undernutrition
Status: COMPLETED
Conditions: Undernutrition
Interventions: OTHER: Oral Nutrition Supplement (ONS) Group|OTHER: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Vaccine (Neoantigen-Targeted ppDC) for the Treatment of H3 G34-mutant Diffuse Hemispheric Glioma
Status: NOT_YET_RECRUITING
Conditions: Diffuse Hemispheric Glioma, H3 G34-Mutant
Interventions: PROCEDURE: Biospecimen Collection|BIOLOGICAL: Dendritic Cell Therapy|PROCEDURE: Leukapheresis|PROCEDURE: Magnetic Resonance Imaging|DRUG: Poly ICLC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: In-Vitro Maturation of Oocytes From Polycystic Ovarian Patients Undergoing IVF
Status: COMPLETED
Conditions: Polycystic Ovarian Syndrome
Interventions: OTHER: In-vitro maturation oocytes
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pulsed Electromagnetic Fields (PEMFs) - A Highly Selective Breast CAncer Treatment pLatform (PASCAL)
Status: RECRUITING
Conditions: Breast Cancer
Interventions: DEVICE: Pulsed electromagnetic fields (PEMFs)|DRUG: Anthracycline-based chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Macitentan, in Healthy Japanese Male Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Macitentan Dose 1|DRUG: Macitentan Dose 2|DRUG: Macitentan Dose 3|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: A Study of Tarceva (Erlotinib) in Combination With Gemcitabine in Unresectable and/or Metastatic Cancer of the Pancreas: Relationship Between Skin Toxicity and Survival
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DRUG: Erlotinib|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: One Year Study of Rifaximin Delayed Release (DR) in Crohn's Disease
Status: TERMINATED
Conditions: Crohn's Disease
Interventions: DRUG: Rifaximin EIR|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Strategy for Blood Pressure Control on Cerebral Oxygen Balance During Aortic Coarctation Repair: A Randomized Study
Status: COMPLETED
Conditions: Cerebral Oxygenation
Interventions: DRUG: nitroprusside|DRUG: nitroglycerine|DRUG: sevoflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective, Monocentric, Interventional Study on Spontaneous Vaginal Clearance of Mycoplasma Genitalium
Status: COMPLETED
Conditions: Mycoplasma Genitalium Infection
Interventions: OTHER: Vaginal self-sampling
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Intradialytic Creatine Supplementation
Status: UNKNOWN
Conditions: Dialysis; Complications
Interventions: DEVICE: Creatine supplementation to dialysate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Clinical Outcome and Fusion Rate of 3D Printed Interbody Fusion Cages and Titanium Coated PEEK Cages
Status: ACTIVE_NOT_RECRUITING
Conditions: Disk Herniated Lumbar|Disc Disease Degenerative|Spondylolisthesis
Interventions: DEVICE: Transforaminal Lumbar Interbody Fusion
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluating the Methylphenidate Patch to Treat Former Stimulant Users With ADHD
Status: COMPLETED
Conditions: Adult Attention Deficit Hyperactivity Disorder (ADHD)
Interventions: DRUG: Daytrana (methylphenidate patch)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial to Investigate the Effect of ESN364 in Early Postmenopausal Women Suffering From Hot Flashes
Status: COMPLETED
Conditions: Hot Flashes
Interventions: DRUG: Fezolinetant|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Timing of Rocuronium After Induction With Propofol on Temporal Summation of Pain
Status: COMPLETED
Conditions: Gynecological Disorder
Interventions: OTHER: The difference of the timing of rocuronium administration after propofol injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Fecal Biotherapy for the Induction of Remission in Active Ulcerative Colitis
Status: COMPLETED
Conditions: Ulcerative Colitis
Interventions: OTHER: Fecal transplant|OTHER: Placebo enema
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Early Glargine (Lantus) in DKA Management in Children With Type 1 Diabetes
Status: COMPLETED
Conditions: Diabetic Ketoacidosis|Type 1 Diabetes Mellitus
Interventions: DRUG: Glargine|DEVICE: Continuous Glucose Monitor (Abbott FreeStyle Libre Pro)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Experimental Evaluation of Back Braces for the Treatment of Spinal Deformity Produced With 3D Printing Technology
Status: COMPLETED
Conditions: Adolescent Idiopathic Scoliosis|Osteogenesis Imperfecta
Interventions: DEVICE: Scoliosis back brace
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Pilot Study to Assess Safety and Feasibility of Normothermic Machine Preservation In Human Liver Transplantation
Status: COMPLETED
Conditions: Liver Transplantation
Interventions: DEVICE: Normothermic Liver perfusion Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Biomarkers of Tumor Response in High Dose Hypofractionated Radiotherapy Word Package 3 : Immune Response
Status: TERMINATED
Conditions: Carcinoma, Hepatocellular|Colorectal Neoplasms|Melanoma|Kidney Neoplasms
Interventions: PROCEDURE: Blood samples collection before radiotherapy|PROCEDURE: Blood samples collection during radiotherapy|PROCEDURE: Blood samples collection after radiotherapy|RADIATION: Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Potential Benefit for Non Invasive Vagus Nerve Stimulation Using GammaCore in the Treatment of Raynaud's Phenomena.
Status: TERMINATED
Conditions: Raynaud Phenomenon|Primary Raynaud Phenomenon|Raynaud Disease|Raynaud Syndrome
Interventions: DEVICE: gammaCore Sapphire|DEVICE: Sham Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Development of Non-invasive Prenatal Screening Test for Microdeletions Based on Fetal DNA Isolated From Maternal Blood
Status: COMPLETED
Conditions: Trisomy 21|Trisomy 18|Trisomy 13|Sex Chromosome Abnormalities|Microdeletion Syndromes
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pharmacokinetics and Safety of Desvenlafaxine in Korean Healthy Subjects Following Single and Multiple Oral Doses of Desvenlafaxine Succinate Sustained Release Tablet
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: desvenlafaxine|DRUG: desvenlafaxine|DRUG: desvenlafaxine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Tumor Detection Using Iodine-131-Labeled Monoclonal Antibody 8H9
Status: TERMINATED
Conditions: CNS Cancer|Neuroblastoma|Sarcoma
Interventions: DRUG: 131I-8H9|DRUG: 8H9
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Myocardial Protection With Perhexiline in Left Ventricular Hypertrophy
Status: UNKNOWN
Conditions: Myocardial Reperfusion Injury|Cardiac Output, Low|Hypertrophy, Left Ventricular
Interventions: DRUG: Perhexiline|DRUG: Placebo marked PEXSIG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Aripiprazole for the Treatment of Schizophrenia With Co-Morbid Social Anxiety
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder|Social Anxiety Disorder
Interventions: DRUG: Aripiprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effect of ALKS 5461 on QT Intervals in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Moxifloxacin|DRUG: ALKS 5461|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Consumption of Phosphatidylserine on the Cognitive Function
Status: COMPLETED
Conditions: Healthy Japanese Subjects
Interventions: DIETARY_SUPPLEMENT: DHAPS® product|DIETARY_SUPPLEMENT: BioPS® product|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Topical Antibiotic Therapy to Reduce Infection After Operative Treatment of Fractures at High Risk of Infection: TOBRA
Status: RECRUITING
Conditions: Post Operative Surgical Site Infection
Interventions: DRUG: Treatment group|DRUG: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess AMG 701 Montherapy, or in Combination With Pomalidomide, With or Without, Dexamethasone in Subjects With Relapsed or Refractory Multiple Myeloma
Status: TERMINATED
Conditions: Relapsed/Refractory Multiple Myeloma
Interventions: DRUG: AMG 701|DRUG: Pomalidomide|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ABT-888 in Patients With Refractory Solid Tumors or Hematologic Cancer
Status: COMPLETED
Conditions: Leukemia|Lymphoma|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: veliparib|OTHER: pharmacological study|PROCEDURE: biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Unfractioned Heparin for Treatment of Sepsis
Status: COMPLETED
Conditions: Sepsis|Bacterial Infections
Interventions: DRUG: Unfractioned heparin|DRUG: saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PRIME: PReservIng Memory in Epilepsy
Status: RECRUITING
Conditions: Mesial Temporal Lobe Epilepsy
Interventions: DEVICE: Low Frequency Stimulation (LFS) of site with the Medtronic Percept PC system|DEVICE: Standard of Care (SOC) High Frequency Stimulation of the Anterior Nucleus of the Thalamus (ANT) with the Medtronic Percept PC system
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of Recombinant Human Brain Natriuretic Peptide on Ventricular Remodeling and Cardiac Function in Patients With Acute Anterior Myocardial Infraction Undergoing Percutaneous Coronary Intervention
Status: RECRUITING
Conditions: Ventricular Remodeling|Myocardial Infarction, Anterior Wall
Interventions: DRUG: Recombinant Human Brain Natriuretic Peptide
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Radiation Therapy With or Without Radiosurgery in Treating Patients With Brain Metastases
Status: COMPLETED
Conditions: Metastatic Cancer
Interventions: PROCEDURE: surgical procedure|RADIATION: radiation therapy|RADIATION: stereotactic radiosurgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PRISM Neurofeedback Training for MDD Anhedonic Patients
Status: RECRUITING
Conditions: Depression|Anhedonia
Interventions: DEVICE: Active RS-EFP|DEVICE: Sham RS-EFP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Docetaxel and Prednisone With or Without Vaccine Therapy in Treating Patients With Metastatic Hormone-Resistant Prostate Cancer
Status: TERMINATED
Conditions: Hormone-Resistant Prostate Cancer|Prostate Adenocarcinoma|Recurrent Prostate Carcinoma|Stage IV Prostate Cancer
Interventions: DRUG: Docetaxel|OTHER: Laboratory Biomarker Analysis|DRUG: Prednisone|BIOLOGICAL: Recombinant Fowlpox-PSA(L155)/TRICOM Vaccine|BIOLOGICAL: Rilimogene Galvacirepvec
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Observational Study of Lumigan® 0.01% for Treatment of Primary Open Angle Glaucoma (POAG) or Ocular Hypertension (OHT)
Status: COMPLETED
Conditions: Open-Angle Glaucoma|Ocular Hypertension
Interventions: DRUG: Bimatoprost 0.01% ophthalmic solution
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Trigeminal Nerve Stimulation for ADHD
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder (ADHD)
Interventions: DEVICE: Active eTNS|DEVICE: Sham eTNS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Treatment Adherence in Schizophrenia With Long Acting Risperidone Microspheres (e-STAR)
Status: COMPLETED
Conditions: Schizophrenia|Tranquilizing Agents|Mental Disorders|Therapeutic Uses|Physiological Effects of Drugs|Psychotropic Drugs|Antipsychotic Agents
Interventions: DRUG: Risperdal Consta
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Dialysis Membranes on Inflammatory and Immune Processes in Hemodialysis
Status: COMPLETED
Conditions: Kidney Failure|Renal Insufficiency, Chronic|Dialysis Related Complication
Interventions: DEVICE: Medium cut-off|DEVICE: High-Flux
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Therapeutic Metabolic Intervention in Patients With Spastic Paraplegia SPG5
Status: COMPLETED
Conditions: Spastic Paraplegia, Hereditary
Interventions: DRUG: Xenbilox|DIETARY_SUPPLEMENT: Resveratrol|DRUG: Tahor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Correlation Between Carbon Dioxide Measured in End of Exhalation and Arterial Blood
Status: COMPLETED
Conditions: Correlation Between Exhaled Carbon Dioxide and in Arterial Blood
Interventions: OTHER: To measure carbon dioxide by capnography and arterial blood|OTHER: to measure carbon dioxide by capnography and arterial blood
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Non-invasive Ventilation Versus High Flow Oxygen
Status: RECRUITING
Conditions: Pneumonia-associated Acute Hypoxemic Respiratory Failure
Interventions: DEVICE: High Flow Oxygen nasal cannula|DEVICE: Noninvasive ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open-Label, Sequential Step, Safety and Efficacy Study to Determine the Optimal Single Dose of Ambisome for Patients With VL
Status: TERMINATED
Conditions: Visceral Leishmaniasis
Interventions: DRUG: Liposomal amphotericin B (Ambisome)|DRUG: Liposomal amphotericin B (Ambisome)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tranexamic Acid for Acute Upper Gastrointestinal Bleed in Cirrhosis
Status: UNKNOWN
Conditions: Liver Cirrhosis
Interventions: DRUG: Tranexamic acid|OTHER: Standard Medical Treatment|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Aerobic Training and Diet on the Immune System in Postmastectomy Patients Receiving Chemotherapy
Status: RECRUITING
Conditions: Immune Deficiency|Diet, Healthy|Breast Cancer
Interventions: OTHER: Aerobic exercises|OTHER: Diet protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Impact of Abiraterone Acetate and Enzalutamide on Health-related Quality of Life, Participant-Reported Outcomes, and Medical Resource Use in Metastatic Castration-resistant Prostate Cancer Participants
Status: COMPLETED
Conditions: Prostatic Neoplasms
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pharmacokinetics of Amiloride Nasal Spray in Healthy Volunteers
Status: COMPLETED
Conditions: Pharmacokinetics
Interventions: DRUG: Amiloride|DRUG: Amiloride|DRUG: Amiloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Trial of BI 6727 (Volasertib) Monotherapy and BI 6727 in Combination With Pemetrexed Compared to Pemetrexed Monotherapy in Advanced NSCLC
Status: COMPLETED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: pemetrexed|DRUG: pemetrexed|DRUG: BI 6727
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Primary Chemotherapy With Docetaxel-Capecitabine and Doxorubicin-Cyclophosphamide in Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer|Breast Neoplasm
Interventions: DRUG: Docetaxel - Dose A|DRUG: Anastrozole|DRUG: cyclophosphamide|DRUG: Docetaxel - Dose B|DRUG: Doxorubicin hydrochloride|DRUG: Tamoxifen Citrate|DRUG: Capecitabine - Dose B|DRUG: Capecitabine - Dose A
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acupuncture Therapy for Post-stroke Mild Cognitive Impairment: a Randomized Controlled Trial
Status: RECRUITING
Conditions: Post-stroke Mild Cognitive Impairment
Interventions: OTHER: electroacupuncture|OTHER: sham acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Radiotherapy and Temozolomide on the Tumor Vasculature and Stem Cells in Human High-grade Astrocytomas
Status: TERMINATED
Conditions: Anaplastic Astrocytoma|Glioblastoma Multiforme|Tumor Angiogenesis
Interventions: DEVICE: Functional MRI (DCE-MRI)|PROCEDURE: Blood sample|PROCEDURE: Tumor sample
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study for Type 2 Diabetic Patients
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Insulin lispro low mixture|DRUG: Insulin glargine|DRUG: Insulin lispro
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mobilization of Stem Cells With Motixafortide (BL-8040) in Combination With G-CSF in Multiple Myeloma Patients
Status: NOT_YET_RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: Motixafortide+G-CSF|DRUG: Placebo+G-CSF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Safety and Activity of Celaderm in Healing Venous Leg Ulcers
Status: COMPLETED
Conditions: Leg Ulcer|Varicose Ulcer
Interventions: DEVICE: Celaderm (Frozen Cultured Epidermal Allograft)|DEVICE: Celaderm (Frozen Cultured Epidermal Allograft)|DEVICE: Control (compression bandaging)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of NGGT001 in Bietti Crystalline Corneoretinal Dystrophy
Status: ACTIVE_NOT_RECRUITING
Conditions: Bietti's Crystalline Dystrophy
Interventions: GENETIC: NGGT001
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of the Application of Xylocaine Impregnated Compress in Reducing Per-procedural Pain During Ultrasound-guided Infiltration of Trigger Finger
Status: UNKNOWN
Conditions: Trigger Finger
Interventions: DRUG: Lidocaïne Aguettant 20 mg/ml|DRUG: NaCl 0,9%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: SAD/MAD Safety and PK Study of RBN-3143 in Healthy and Atopic Dermatitis Subjects
Status: RECRUITING
Conditions: Atopic Dermatitis
Interventions: DRUG: RBN-3143
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Romidepsin and Erlotinib Hydrochloride in Treating Patients With Stage III or Stage IV Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer|Metastatic Cancer
Interventions: COMBINATION_PRODUCT: Erlotinib plus Romidepsin (8 mg/m^2)|COMBINATION_PRODUCT: Erlotinib plus Romidepsin (10 mg/m^2)|COMBINATION_PRODUCT: Erlotinib plus Romidepsin (10 mg/m^2) + Antiemetic prophylaxis|COMBINATION_PRODUCT: (Erlotinib plus Romidepsin (8mg/m^2)) + Antiemetic prophylaxis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HFNO Improves Blood Oxygen Saturation During Asphyxia During Pulmonary Surgery With Double-lumen Endotracheal Intubation
Status: NOT_YET_RECRUITING
Conditions: Lung Neoplasms|Pneumothorax
Interventions: DEVICE: HFNO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Radiofrecuency and Supervised Exercise Versus Supervised Exercise in the Treatment of Patellofemoral Pain Syndrome.
Status: COMPLETED
Conditions: Patellofemoral Pain Syndrome
Interventions: DEVICE: Diathermy|OTHER: Supervised knee exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Effect of Delayed Release Pancrelipase on Maldigestion in Patients With Exocrine Pancreatic Insufficiency Due to Chronic Pancreatitis and Pancreatectomy
Status: COMPLETED
Conditions: Chronic Pancreatitis|Pancreatectomy|Pancreatic Exocrine Insufficiency
Interventions: DRUG: Pancrelipase delayed release capsule|DRUG: Placebo Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Biofeedback and Virtual Reality as Facilitators of Emotional Recognition in the Treatment of Aggressive Outbursts
Status: RECRUITING
Conditions: Passive-Aggressive Personality Disorder
Interventions: BEHAVIORAL: Use of biofeedback and virtual reality in the treatment of aggressive outbursts
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Endoscopic Prevention of Esophageal Cancer at Tenwek Hospital
Status: SUSPENDED
Conditions: Esophageal Cancer|Esophageal Squamous Dysplasia
Interventions: PROCEDURE: Endoscopic Mucosal Resection (EMR)|DEVICE: Radiofrequency ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination of Paclitaxel-bevacizumab ± Atezolizumab in Patients With Advanced NSCLC Progressing After Immunotherapy & Chemotherapy
Status: RECRUITING
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: Paclitaxel|DRUG: Bevacizumab|DRUG: Atezolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Personalized Spacing of Eculizumab Infusions Based on Therapeutic Pharmacological Monitoring (EspacECU)
Status: ACTIVE_NOT_RECRUITING
Conditions: Hemolytic-Uremic Syndrome, Atypical
Interventions: DRUG: Spacing of Eculizumab infusions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: App-based Mental Health Promotion in Young European Adults
Status: UNKNOWN
Conditions: Wellbeing|Mental Disorder
Interventions: BEHAVIORAL: Tailored Emotional Competence Self-help|BEHAVIORAL: Cognitive-behavioural Approach|BEHAVIORAL: Self-monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: To Evaluate the Efficacy and Safety of Nemolizumab for 12 Weeks in Participants With Chronic Kidney Disease With Associated Moderate to Severe Pruritus
Status: COMPLETED
Conditions: Chronic Kidney Disease Associated Moderate to Severe Pruritus
Interventions: DRUG: Nemolizumab|DRUG: Nemolizumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Sterimar vs Saline Sprays in Nasal Surgical Aftercare - a Blinded, Randomised Trial
Status: UNKNOWN
Conditions: Nasal Surgery
Interventions: DRUG: Sterimar Spray|DRUG: Generic homemade nasal saline spray (salt and water)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Dasatinib in Treating Patients With Advanced Liver Cancer That Cannot Be Removed by Surgery
Status: TERMINATED
Conditions: Adult Primary Hepatocellular Carcinoma|Advanced Adult Primary Liver Cancer|Recurrent Adult Primary Liver Cancer
Interventions: DRUG: dasatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Thiotepa Followed by Peripheral Stem Cell or Bone Marrow Transplant in Treating Patients With Malignant Glioma
Status: COMPLETED
Conditions: Brain and Central Nervous System Tumors
Interventions: BIOLOGICAL: filgrastim|BIOLOGICAL: sargramostim|DRUG: cyclophosphamide|DRUG: thiotepa|PROCEDURE: autologous bone marrow transplantation|PROCEDURE: bone marrow ablation with stem cell support|PROCEDURE: peripheral blood stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized, Single Center Study About the Impact of an E-learning Dedicated to Myocardial Infarction Patient
Status: COMPLETED
Conditions: Acute Myocardial Infarction
Interventions: OTHER: E-learning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of the PneumRx Lung Volume Reduction Coil to Treat Emphysema
Status: COMPLETED
Conditions: Emphysema
Interventions: DEVICE: Lung Volume Reduction Coil (LVRC)|DEVICE: Coils
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of ACT-293987 (NS-304) in Pulmonary Arterial Hypertension (PAH)
Status: COMPLETED
Conditions: Pulmonary Arterial Hypertension
Interventions: DEVICE: ACT-293987 (NS-304)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: |Primary Purpose: OTHER
Clinical trial: Intensive Glycemic Targets in Overweight and Obese Women With Gestational Diabetes
Status: RECRUITING
Conditions: Gestational Diabetes|Pregnancy, High Risk|Overweight and Obesity
Interventions: OTHER: Intensive glycemic targets|OTHER: Standard glycemic targets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cisplatin, Pemetrexed Disodium, and Radiation Therapy Followed by Docetaxel in Treating Patients With Stage III Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DRUG: Cisplatin|DRUG: Docetaxel|DRUG: Pemetrexed disodium|RADIATION: Radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 2 Year Study to Evaluate the Effects of GPI 1485 on [123I]b-CIT/SPECTScanning and Clinical Efficacy in Patients With PD
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DRUG: GPI 1485
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of the Osteopathic Treatment in Patients With Nonspecific Cervical Pain
Status: UNKNOWN
Conditions: Manual Therapies|Neck Pain
Interventions: OTHER: Osteopathic Manipulative Treatment (OMT) - Temp1|OTHER: Combined Exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cavilon Breast Trial: Comparison of Cavilon Durable Barrier Cream to Glycerine ("Sorbolene") Cream
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Cavilon (TM) Durable Barrier Cream|DRUG: Sorbolene|RADIATION: Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Chloroquine (CQ) and Azithromycin (AZ) Combination for Malaria Prophylaxis
Status: WITHDRAWN
Conditions: Malaria
Interventions: DRUG: Chloroquine-Azithromycin (CQ/AZ)|DRUG: Chloroquine (CQ)|DRUG: atovaquone-proguanil (Malarone®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Abuse Potential of Cebranopadol in Humans
Status: COMPLETED
Conditions: Human Abuse Potential
Interventions: DRUG: Oxycodone 40 mg|DRUG: Tramadol 600 mg|DRUG: Placebo|DRUG: Cebranopadol 600 µg|DRUG: Cebranopadol 1000 µg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Use of Autologous Bone Marrow Derived Stem Cell in Treatment of Age Related Macular Degeneration
Status: UNKNOWN
Conditions: Age Related Macular Degeneration
Interventions: DRUG: autologous bone marrow derived stem cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Administration of GRASPA (Suspension of Erythrocytes Encapsulating L-asparaginase)in Patients With Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DRUG: GRASPA
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose-Escalation and Dose-Expansion Study of ZX-101A in Patients With Relapsed/Resistant or Refractory Advanced Hematologic Malignancies
Status: TERMINATED
Conditions: Non-hodgkin Lymphoma|Chronic Lymphocytic Leukemia|Small Lymphocytic Lymphoma
Interventions: DRUG: ZX-101A
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ceftobiprole in Hospital Acquired Pneumonia
Status: COMPLETED
Conditions: Pneumonia
Interventions: DRUG: ceftobiprole plus placebo|DRUG: linezolid plus ceftazidime
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of SR1375
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: SR1375|DRUG: Matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of RNA-lipid Particle (RNA-LP) Vaccines for Recurrent Pulmonary Osteosarcoma (OSA)
Status: NOT_YET_RECRUITING
Conditions: Pulmonary Osteosarcoma
Interventions: BIOLOGICAL: RNA-LP vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT