pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: QBSafe: a Randomized Trial of a Novel Intervention to Improve Care for People Living With Type 2 Diabetes.
Status: RECRUITING
Conditions: Type2Diabetes|Diabetes
Interventions: BEHAVIORAL: QBSafe
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Pilot Study Of A Novel Treatment Regimen, Maraviroc + Ritonavir Boosted Atazanavir, In Treatment Naive HIV-Infected Patients
Status: COMPLETED
Conditions: Human Immunodeficiency Virus-1
Interventions: DRUG: maraviroc|DRUG: maraviroc
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparation Analgesia Efficiency With Propofol Combine Sevoflurane vs Propofol
Status: COMPLETED
Conditions: Nociceptive Pain|Analgesic Adverse Reaction|Inhalant Use
Interventions: DRUG: 5mg/kg/h Propofol|DRUG: Sevoflurane|DRUG: 2 mg/kg/h Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Biological Outcomes of Pramlintide in Resectable Cutaneous Squamous Cell Carcinoma: A Pilot Study
Status: WITHDRAWN
Conditions: Cutaneous Squamous Cell Carcinoma
Interventions: DRUG: Pramlintide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy or Observation in Treating Patients With Early Stage Non-Small Cell Lung Cancer
Status: TERMINATED
Conditions: Lung Cancer
Interventions: DRUG: cisplatin|DRUG: docetaxel|DRUG: gemcitabine hydrochloride|DRUG: pemetrexed disodium|DRUG: vinorelbine tartrate|PROCEDURE: standard follow-up care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose Escalation Study With QLT0074 for Benign Prostatic Hyperplasia
Status: COMPLETED
Conditions: Benign Prostatic Hyperplasia
Interventions: DRUG: QLT0074|DRUG: Photodynamic therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: OPEN & ASK: Improving Patient-Centered Communication in Primary Care
Status: COMPLETED
Conditions: Patient Engagement|Physician's Role|Physician-Patient Relations|Patient Activation
Interventions: BEHAVIORAL: OPEN High Touch|BEHAVIORAL: OPEN High Tech|BEHAVIORAL: ASK Poster in Exam Rooms
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Improving Tolerability of Bowel Preparation Laxative for Colonoscopy
Status: COMPLETED
Conditions: Colonoscopy|Bowel Preparation
Interventions: OTHER: Pattern of flavoring of bowel laxative
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Problem-Solving Therapy for Patients With Chronic Disease and Poor Mental Well-being in General Practice
Status: ENROLLING_BY_INVITATION
Conditions: Mental Health Impairment|Diabetes Type 2|Ischemic Heart Disease
Interventions: BEHAVIORAL: Problem Solving Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Predictors and Prognostic Factors of Myasthenia Gravis Outcome
Status: RECRUITING
Conditions: Myasthenia Gravis|Autoimmune Diseases of the Nervous System|Neuromuscular Junction Diseases|Thymoma|Thymus Hyperplasia|Nervous System Diseases|Myasthenia Gravis, Generalized|Myasthenia Gravis, Ocular|Myasthenia Gravis Crisis|Myasthenia Gravis With Exacerbation (Disorder)|Myasthenia Gravis, Adult Form|Myasthenia Gravis, Juvenile Form
Interventions: COMBINATION_PRODUCT: Drug treatment of myasthenia gravis and treatment of crisis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Nicotine Plasma Concentrations and Subjective Effects for Three Menthol Electronic Cigarettes vs Combustible Menthol Cigarettes and Nicotine Gum
Status: COMPLETED
Conditions: Smoking
Interventions: OTHER: Own Brand Menthol Cigarette|OTHER: Electronic Menthol Cigarette #1|OTHER: Electronic Menthol Cigarette #2|OTHER: Electronic Menthol Cigarette #3|OTHER: Leading U.S. Nicotine Gum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Magnetic Resonance Imaging Study of Cognitive-Behavior Therapy for Major Depressive Disorder
Status: UNKNOWN
Conditions: Major Depressive Disorder
Interventions: DRUG: SSRI antidepressants|BEHAVIORAL: Cognitive-Behavior Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Inhaled Nitric Oxide on Dyspnea and Exercise Tolerance in COPD
Status: COMPLETED
Conditions: Dyspnea
Interventions: DRUG: Nitric Oxide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Percutaneous Coronary Intervention Combined With Thrombolysis at Different Time
Status: UNKNOWN
Conditions: Acute ST Segment Elevation Myocardial Infarction
Interventions: COMBINATION_PRODUCT: thrombolysis and PCI of A type|COMBINATION_PRODUCT: thrombolysis and PCI of B type
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase III Study Comparing Efficacy and Safety of AFOLIA vs Gonal-f® RFF in Women (35 to 42) Undergoing IVF
Status: COMPLETED
Conditions: Infertility
Interventions: DRUG: AFOLIA|DRUG: Gonal-f® RFF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Changes of Left Atrial Function and Quality of Life in Patients With Left Atrial Appendage Occlusion
Status: UNKNOWN
Conditions: Atrial Fibrillation
Interventions: PROCEDURE: Left atrial appendage closure group|PROCEDURE: Radiofrequency ablation group|PROCEDURE: LAAC combined with radiofrequency ablation group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Zuretinol Acetate in Subjects With Inherited Retinal Disease
Status: WITHDRAWN
Conditions: Retinal Disorder
Interventions: DRUG: Placebos|DRUG: ZA Low dose|DRUG: ZA high dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1/2, Open-label, Safety and Dosing Study of Autologous CART Cells (Desmoglein 3 Chimeric Autoantibody Receptor T Cells [DSG3-CAART] or CD19-specific Chimeric Antigen Receptor T Cells [CABA-201]) in Subjects With Active, Pemphigus Vulgaris (RESET-PV)
Status: RECRUITING
Conditions: Pemphigus Vulgaris
Interventions: BIOLOGICAL: DSG3-CAART or CABA-201
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sunscreen RV 2457C in Photoinduced CLE
Status: COMPLETED
Conditions: Cutaneous Lupus Erythematosus|Skin Lesion|Experimental Photoinduction|Protective Sunscreen
Interventions: DRUG: sunscreen RV 2547C
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: To Evaluate the Efficacy and Safety of HSK16149 With L-carnitine in Diabetic Peripheral Neuralgia Patients in China
Status: RECRUITING
Conditions: Diabetic Peripheral Neuropathic Pain
Interventions: DRUG: HSK16149 20mg BID
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 9MW2821 Combined With Toripalimab Injection in Subjects With Local Advanced or Metastatic Urothelial Cancer
Status: NOT_YET_RECRUITING
Conditions: Advanced Urothelial Carcinoma
Interventions: DRUG: 9MW2821|DRUG: Toripalimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Screening for Colonization With Resistant Enterobacterales in Neutropenic Patients With Hematologic Malignancies
Status: COMPLETED
Conditions: Hematologic Malignancy|Leukemia, Acute|Neutropenia|Bloodstream Infection
Interventions: OTHER: No intervention.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Exercise and/or Liraglutide on Vascular Dysfunction and Insulin Sensitivity in Type 2 Diabetes ( ZQL007)
Status: RECRUITING
Conditions: Type2 Diabetes
Interventions: OTHER: Exercise|DRUG: Liraglutide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multicentric Evaluation of the True Negative Predictive Value of Multiparametric MRI for the Detection of Prostate Cancer Using Cystoprostatectomy Specimen as Reference
Status: UNKNOWN
Conditions: Prostate Cancer
Interventions: DEVICE: mpMRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Evaluate the Effect of Testosterone on Muscle Fractional Synthetic Rate (MK-0000-064)
Status: COMPLETED
Conditions: Muscle Anabolism
Interventions: DRUG: Comparator: Testosterone 300 mg, intramuscular injection|DRUG: Comparator: Testosterone 100 mg, Intramuscular injection|DRUG: Comparator: Placebo given by Intramuscular Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of Experimental Medication BMS-986036 in Adults With Nonalcoholic Steatohepatitis (NASH) and Liver Cirrhosis
Status: COMPLETED
Conditions: Hepatic Cirrhosis|Liver Fibrosis|Nonalcoholic Fatty Liver Disease (NAFLD)|Nonalcoholic Steatohepatitis
Interventions: DRUG: BMS-986036|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Role of Colchicine in Reducing The Rate of Myocardial Reperfusion Injury
Status: ENROLLING_BY_INVITATION
Conditions: Reperfusion Injury, Myocardial
Interventions: DRUG: Colchicine|DRUG: Placebo (lactose)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Arthroscopic Surgery and Platelet Rich Plasma In Rotator Cuff Tear Evaluation
Status: COMPLETED
Conditions: Rotator Cuff Tear
Interventions: BIOLOGICAL: Autologous conditioned plasma (ACP)|OTHER: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study on the Long-term Efficacy of Nebivolol After Withdrawal of Therapy
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Nebivolol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Promephy - Metabolic Fate of Plant-based Proteins
Status: RECRUITING
Conditions: Amino Acid Change|Gastrointestinal Dysfunction
Interventions: DIETARY_SUPPLEMENT: Dairy based protein|DIETARY_SUPPLEMENT: Mixed protein|DIETARY_SUPPLEMENT: Plant-based protein 1|DIETARY_SUPPLEMENT: Plant-based protein 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Contrast-Enhanced Subharmonic Ultrasound Imaging in Improving Characterization of Adnexal Masses in Patients Undergoing Surgery
Status: COMPLETED
Conditions: Adnexal Mass
Interventions: DRUG: Perflutren Lipid Microspheres|PROCEDURE: Contrast-Enhanced Subharmonic Ultrasound Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Thrombus Aspiration in ThrOmbus Containing culpRiT Lesions in Non-ST-Elevation Myocardial Infarction (TATORT-NSTEMI)
Status: COMPLETED
Conditions: Non-ST-elevation Myocardial Infarction
Interventions: PROCEDURE: Thrombectomy|PROCEDURE: Standard percutaneous coronary intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Telehome Monitoring in Patients on Peritoneal Dialysis: A Multicentre Randomized Controlled Trial
Status: COMPLETED
Conditions: End-Stage Renal Disease
Interventions: DEVICE: Telehome Monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Patient-Informed Educational Intervention for the Improvement of Cervical Cancer Literacy
Status: WITHDRAWN
Conditions: Stage IB Cervical Cancer FIGO 2018|Stage IB1 Cervical Cancer FIGO 2018|Stage IB2 Cervical Cancer FIGO 2018|Stage IB3 Cervical Cancer FIGO 2018|Stage II Cervical Cancer FIGO 2018|Stage IIA Cervical Cancer FIGO 2018|Stage IIA1 Cervical Cancer FIGO 2018|Stage IIA2 Cervical Cancer FIGO 2018|Stage IIB Cervical Cancer FIGO 2018|Stage III Cervical Cancer FIGO 2018|Stage IIIA Cervical Cancer FIGO 2018|Stage IIIB Cervical Cancer FIGO 2018|Stage IIIC Cervical Cancer FIGO 2018|Stage IIIC1 Cervical Cancer FIGO 2018|Stage IIIC2 Cervical Cancer FIGO 2018|Stage IVA Cervical Cancer FIGO 2018
Interventions: OTHER: Educational Intervention|OTHER: Survey Administration
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Diet Plus Sibutramine on Hormonal and Metabolic Features in Overweight and Obese Women With PCOS
Status: COMPLETED
Conditions: Obesity|Polycystic Ovary Syndrome
Interventions: DRUG: Sibutramine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: e-ITAG Allergen Immunotherapy in the Management of Allergic Asthma
Status: RECRUITING
Conditions: Study the Efficacy of ITA in Patients With Allergic Asthma or Allergic Rhinitis or Allergic Rhinitis Compared With Conventional Treatment
Interventions: DRUG: Immunotherapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy, Pharmacokinetics, and Safety of BI 695500 in Patients With Rheumatoid Arthritis
Status: TERMINATED
Conditions: Arthritis, Rheumatoid
Interventions: DRUG: BI 695500|DRUG: BI 695500|DRUG: Rituxan®|DRUG: Rituxan®|DRUG: MabThera®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Target Therapy With GEMOX in Recectable Gallbladder Carcinoma Patients Monitored by ctDNA
Status: RECRUITING
Conditions: Gallbladder Carcinoma
Interventions: DRUG: gemcitabine and oxaliplatin.|DRUG: Afatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I Study of INO-1800 With or Without INO-9112 + EP in Chronic Hepatitis B Subjects
Status: COMPLETED
Conditions: Hepatitis B
Interventions: BIOLOGICAL: INO-1800|BIOLOGICAL: INO-9112|DRUG: Nucleos(t)ide Analogue Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Laboratory Assessment of Pilairo Q CPAP Mask Performance and Ease of Use.
Status: COMPLETED
Conditions: Obstructive Sleep Apnea
Interventions: DEVICE: FPH Pilairo Q CPAP mask|DEVICE: Any other market released nasal or nasal-pillow CPAP mask
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: EVALUATION OF TWO DIFFERENT ATTACHMENT SYSTEMS IN MANDIBULAR OVERDENTURES RETAINED WITH TWO INCLINED IMPLANTS
Status: RECRUITING
Conditions: Inclined Implants
Interventions: OTHER: Novaloc Attachment|OTHER: Locator Attachment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Serratus Anterior Block and Catheter Use in Rib Fractures in the Emergency Department
Status: SUSPENDED
Conditions: Anesthesia|Rib Fractures
Interventions: PROCEDURE: Serratus Anterior Plane Catheter|PROCEDURE: Thoracic Epidural Catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Preliminary Efficacy of a Response-guided Dose Titration of KER-047 in the Treatment of Functional IDA (Iron Deficiency Anemia).
Status: WITHDRAWN
Conditions: Iron Deficiency Anemia
Interventions: DRUG: KER-047
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Wearable Cardiac Monitor to Enhance Detection of Arrhythmia Recurrence After Catheter Ablation of Atrial Fibrillation
Status: NOT_YET_RECRUITING
Conditions: Atrial Fibrillation|Arrhythmias, Cardiac|Heart Diseases|Cardiovascular Diseases|Stroke Prevention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Treatment of Osteoarthritic Knee With High Tibial Osteotomy and Implantation of Allogenic Human Umbilical Cord Blood-derived Stem Cells.
Status: UNKNOWN
Conditions: Osteoarthritis, Knee
Interventions: PROCEDURE: umbilical cord blood stem cell implantation for osteoarthritis treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safingol and Cisplatin in Treating Patients With Locally Advanced or Metastatic Solid Tumors
Status: COMPLETED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: cisplatin|DRUG: safingol
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of PH With Angiotensin II Receptor Blocker and Neprilysin Inhibitor in HFpEF Patients With CardioMEMS Device
Status: COMPLETED
Conditions: Pulmonary Hypertension
Interventions: DRUG: Sacubitril / Valsartan Oral Tablet [Entresto]
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Determine the Most Effective Intervention for Hemorrhage Control Readiness for Laypersons: The PATTS Trial
Status: COMPLETED
Conditions: Traumatic Hemorrhage
Interventions: BEHAVIORAL: Flashcards|BEHAVIORAL: Audio-kit|BEHAVIORAL: B-Con training|BEHAVIORAL: B-Con training retention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Safety of SCH 530348 in Subjects Undergoing Non-Emergent Percutaneous Coronary Intervention (Study P03573)
Status: COMPLETED
Conditions: Arterial Obstructive Diseases|Coronary Disease
Interventions: DRUG: SCH 530348
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Split-belt Treadmill Training to Rehabilitate Freezing of Gait and Balance in Parkinson's Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Parkinson Disease|Freezing of Gait|Gait, Unsteady
Interventions: OTHER: Split-belt treadmill training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Impact of Contrast Media Used in Epidural Steroid Injections on Thyroid Function Tests
Status: COMPLETED
Conditions: Lumbar Radiculopathy|Lumbar Spinal Stenosis|Cervical Radiculopathy|Cervical Stenosis
Interventions: PROCEDURE: Epidural Steroid Injection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study With Lu AF11167 for the Treatment of Negative Symptoms in Patients With Schizophrenia
Status: TERMINATED
Conditions: Schizophrenia
Interventions: DRUG: Lu AF11167 (1-2 mg/day)|DRUG: Lu AF11167 (3-4 mg/day)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Recombinant Vesicular Stomatitis Virus (rVSV)-Marburg Virus Vaccine Candidate (PHV01) in Healthy Adult Subjects
Status: RECRUITING
Conditions: Marburg Virus Disease
Interventions: BIOLOGICAL: PHV01|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Positron Emission Tomography in Women With Advanced HER2-Positive Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer|Stage IV Breast Cancer
Interventions: PROCEDURE: positron emission tomography|RADIATION: copper Cu 64-DOTA-trastuzumab|PROCEDURE: Biopsy|OTHER: Immunohistochemistry staining method|OTHER: laboratory biomarker analysis|GENETIC: mutation analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Personalised Immunotherapy for SARS-CoV-2 (COVID-19) Associated With Organ Dysfunction
Status: COMPLETED
Conditions: COVID-19|Virus Diseases|Macrophage Activation Syndrome|Corona Virus Infection
Interventions: DRUG: Anakinra|DRUG: Tocilizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Return to Work for Persistent Spinal Pain Syndrome Type II Patients
Status: RECRUITING
Conditions: Failed Back Surgery Syndrome|Spinal Cord Stimulation
Interventions: OTHER: Usual Care trajectory|OTHER: A biopsychosocial rehabilitation program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of H2 Receptor Antagonist in Prevention of Thienopyridine-related Peptic Ulcer
Status: COMPLETED
Conditions: Peptic Ulcer
Interventions: DRUG: histamine-2 receptor antagonist|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Olfactory and Taste Disturbances in Sjogren's Syndrome
Status: UNKNOWN
Conditions: Sjogren's Syndrome
Interventions: OTHER: Evaluation of olfactory function|OTHER: Evaluation of taste function|OTHER: Evaluation of (intra-nasal and oral) trigeminal functions
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study Evaluating Pyrotinib in Combination With Capecitabine In Patients With HER2 Positive Metastatic Breast Cancer
Status: COMPLETED
Conditions: Metastatic Breast Cancer
Interventions: DRUG: pyrotinib combined with capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Suboxone User Perioperative Early Referral and Enhanced Recovery After Surgery- Orthopaedic Trauma Surgery Population
Status: WITHDRAWN
Conditions: Addiction Opiate|Chronic Pain|Fractures, Bone|Buprenorphine Dependence
Interventions: DRUG: Sufentanil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Study of CNTO 328 (Siltuximab) in Relapsed or Refractory Multiple Myeloma
Status: TERMINATED
Conditions: Multiple Myeloma
Interventions: DRUG: Siltuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I Clinical Trial of FWD1802 in Patients With ER+/HER2- BC.
Status: RECRUITING
Conditions: Metastatic Breast Cancer|Locally Advanced Breast Cancer|Breast Cancer Stage I|ER+ Breast Cancer
Interventions: DRUG: FWD1802|DRUG: palbocilib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Total Body Irradiation/Fludarabine Based Ablative Haploidentical Transplant for Hematologic Diseases
Status: COMPLETED
Conditions: Chronic Leukemia|Acute Leukemia|Hodgkin's Disease|Non-Hodgkin's Lymphoma|Myelodysplastic Syndrome
Interventions: PROCEDURE: Peripheral Blood Stem Cell Transplant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Efficacy and Safety of Two Topical Creams for Pediatric Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DEVICE: EpiCeram Skin Barrier Emulsion|DRUG: Desonide Cream 0.05%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Mirror-image Study of Paliperidone Palmitate and Risperidone Long-acting Injection
Status: UNKNOWN
Conditions: Schizophrenia Spectrum and Other Psychotic Disorders
Interventions: DRUG: Paliperidone Palmitate|DRUG: Risperidal Consta|DRUG: Antipsychotic
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Cefepime/AAI101 Phase 2 Study in Hospitalized Adults With cUTI
Status: COMPLETED
Conditions: Urinary Tract Infections
Interventions: DRUG: Cefepime 1G - 2G / AAI101 0.5G - 0.75G|DRUG: cefepime 1 g or cefepime 2 g
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Everolimus and Temozolomide in Advanced Gastroenteropancreatic Neuroendocrine Carcinoma (G3)
Status: COMPLETED
Conditions: Neuroendocrine Carcinoma
Interventions: DRUG: Everolimus , temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antibiotic Prophylaxis in Pediatric Open Fractures
Status: ENROLLING_BY_INVITATION
Conditions: Fractures, Open|Infections
Interventions: DRUG: Cefazolin|DRUG: Cephalexin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of FORE8394 as a Single Agent in Patients With Advanced Unresectable Solid Tumors
Status: COMPLETED
Conditions: Advanced Unresectable Solid Tumors|BRAF-mutated Tumors
Interventions: DRUG: FORE8394
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Darolutamide Combined With ADT in High-risk/Very High-risk Localized Prostate Cancer
Status: RECRUITING
Conditions: Prostate Cancer
Interventions: DRUG: Darolutamide 300 mg|OTHER: Androgen deprivation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Outcomes of Degenerative Disc Disease Patients Treated With an Anterior-Only Fusion Using InQu Bone Graft
Status: UNKNOWN
Conditions: Degenerative Disc Disease
Interventions: PROCEDURE: One-level or two-level anterior lumbar interbody fusion|BIOLOGICAL: InQu Bone Graft Extender and Substitute mixed with BMAC|DEVICE: Synthes Spinal Instrumentation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparing Covered Self-expandable Metallic Stent (SEMS) Above/Across the Sphincter of Oddi
Status: COMPLETED
Conditions: Cancer of Bile Duct|Pancreatic Cancer
Interventions: DEVICE: PTFE Covered ComVi [full covered] Biliary Stent|DEVICE: PTFE Covered ComVi [full covered] Biliary Stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Change in Airway Peripheral Tone in COPD
Status: UNKNOWN
Conditions: COPD|COPD, Early-Onset
Interventions: DIAGNOSTIC_TEST: oscillometry|DIAGNOSTIC_TEST: multiple breath washout testing|DIAGNOSTIC_TEST: spirometry|DIAGNOSTIC_TEST: body plethysmography|DIAGNOSTIC_TEST: fractional exhaled nitric oxide|DIAGNOSTIC_TEST: transfer factor|DIAGNOSTIC_TEST: health status|DIAGNOSTIC_TEST: computed tomography|DIAGNOSTIC_TEST: induced sputum
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical Study on the Application of a Non-Invasive Micro-Focused Ultrasound With Visualization System for Skin Laxity (ULT-215)
Status: COMPLETED
Conditions: Facial Skin Laxity
Interventions: DEVICE: Microfocused ultrasound with visualization
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multiple Dosing (14 Days) Study to Assess Efficacy and Safety of Three Dose Levels of AZD7594, Given Once Daily by Inhalation, in Patients With Mild to Moderate Asthma
Status: COMPLETED
Conditions: Asthma|Efficacy|Safety
Interventions: DRUG: 800 μg AZD7594 once daily|DRUG: 250 µg AZD7594 once daily|DRUG: 58 µg AZD7594 once daily|DRUG: Placebo once daily|DRUG: Salbutamol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: CT to Assess the Efficacy and Safety of Adding GMA to Infliximab in Paediatric Patients With Steroid-refractory Ulcerative Colitis
Status: RECRUITING
Conditions: Ulcerative Colitis
Interventions: DEVICE: Adacolumn
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long-Term Effects of Torso-Weighting
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DEVICE: Torso Weights|DEVICE: Sham Weights|DEVICE: Fitbit Flex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of a Standardized Centella Asiatica Extract in Patients With Temporomandibular Disorder
Status: COMPLETED
Conditions: Temporomandibular Disorder
Interventions: DRUG: ECa 233|DRUG: Ibuprofen|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Treating Insomnia & Nightmares After Trauma: Impact on Symptoms & Quality of Life
Status: COMPLETED
Conditions: Nightmares|Insomnia|Posttraumatic Stress Disorder
Interventions: BEHAVIORAL: PTSD + IRT/CBT-I|BEHAVIORAL: PTSD + Supportive Care Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Thoracic Peri-Operative Integrative Surgical Care Evaluation Trial - Stage II
Status: RECRUITING
Conditions: Lung Cancer|Gastric Cancer|Esophageal Cancer
Interventions: DIETARY_SUPPLEMENT: Vitamin D3 Drops|DIETARY_SUPPLEMENT: Coriolus Versicolor|DIETARY_SUPPLEMENT: Trident SAP 66:33 Lemon|DIETARY_SUPPLEMENT: Probiotic Pro12|DIETARY_SUPPLEMENT: Provitalix Pure Whey Protein|DIETARY_SUPPLEMENT: Theracurmin 2X|DIETARY_SUPPLEMENT: Green Tea Extract|OTHER: Nutrition Recommendations|OTHER: Physical Activity Recommendations|BEHAVIORAL: Psychological Recommendations
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Health Related Quality of Life Effects of Off-the-shelf Computer Gaming in Alzheimer and Related Disorders Populations
Status: TERMINATED
Conditions: Disease Alzheimer
Interventions: BEHAVIORAL: Physical Therapy (standard)|BEHAVIORAL: Balance and Gait training in Individualized sessions|BEHAVIORAL: Kinect|BEHAVIORAL: Group Xbox Kinect
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Exercise-based Motivational Interviewing for Fibromyalgia
Status: COMPLETED
Conditions: Fibromyalgia
Interventions: BEHAVIORAL: Attention Control Counseling|BEHAVIORAL: Motivational Interviewing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Efficacy of CELZ-201 in Patients With Recent Onset Type 1 Diabetes
Status: RECRUITING
Conditions: Type 1 Diabetes|Diabetes Mellitus, Type 1
Interventions: BIOLOGICAL: CELZ-201 Administration|OTHER: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I Clinical Trial of a 13-valent Pneumococcal Conjugate Vaccine and 14-valent Pneumococcal Conjugate Vaccine in Adults
Status: COMPLETED
Conditions: Pneumococcal Infections
Interventions: BIOLOGICAL: Pneumococcal conjugate vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Comparison of Two Strategies of One-lung Ventilation in Patients Undergoing Carcinological Lung Resection Surgery.
Status: RECRUITING
Conditions: Lung Diseases
Interventions: PROCEDURE: "Open-lung" protective ventilation strategy|PROCEDURE: "Standard" protective ventilation strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Aezea® (Cenersen) and Chemotherapy for AML Subjects ≥ 55 Years of Age With No Response to Frontline Induction Course
Status: WITHDRAWN
Conditions: Acute Myelogenous Leukemia
Interventions: DRUG: cenersen|DRUG: placebo|DRUG: idarubicin, cytarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility Study of Telemedicine for Dialysis Patients Awaiting Transplantation
Status: COMPLETED
Conditions: End Stage Renal Disease|Kidney Disease, Chronic
Interventions: BEHAVIORAL: Usual Care Visit|BEHAVIORAL: Telemedicine Visit
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Phase II NKTR-102 In Bevacizumab-Resistant High Grade Glioma
Status: COMPLETED
Conditions: Anaplastic Astrocytomas|Anaplastic Oligodendrogliomas|Glioblastomas (GBM)
Interventions: DRUG: Etirinotecan pegol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Capecitabine, Oxaliplatin, and Radiation Therapy in Treating Patients With Esophageal or Gastroesophageal Junction Cancer
Status: COMPLETED
Conditions: Esophageal Cancer
Interventions: DRUG: Induction Therapy - Capecitabine|DRUG: Induction Therapy - Oxaliplatin|DRUG: Combination Therapy - Capecitabine|DRUG: Combination Therapy - Oxaliplatin|RADIATION: Combination Therapy - Radiation|PROCEDURE: Evaluation for response and surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Of 4 CP-690,550 Doses Vs. Placebo, Each Combined With Methotrexate, For The Treatment Of Rheumatoid Arthritis in Japan
Status: COMPLETED
Conditions: Arthritis, Rheumatoid
Interventions: DRUG: Placebo|DRUG: CP-690,550|DRUG: CP-690,550|DRUG: CP-690,550|DRUG: CP-690,550
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial for Advanced or Metastatic Pancreatic Cancer
Status: NOT_YET_RECRUITING
Conditions: Pancreas Cancer
Interventions: DRUG: LTC004 + MIL-97|DRUG: LTC004 + MIL-97+chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Continuous Apomorphine During the Night on Sleep Disorders in Insomniac Patients With Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: DRUG: Apomorphine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Ginger on Intraoperative and Postoperative Nausea and Vomiting in Elective Cesarean Section Patients
Status: COMPLETED
Conditions: Nausea|Vomiting
Interventions: DRUG: Ginger|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Long-term Oral Esomeprazole for Prevention of Peptic Ulcer Rebleeding in High-risk Patients
Status: COMPLETED
Conditions: Peptic Ulcer Hemorrhage
Interventions: DRUG: oral esomeprazole 20 mg twice daily|DRUG: oral esomeprazole 20 mg once daily
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Treatment of Recurrent Pregnancy Loss Using Mesenchymal Stem Cells
Status: UNKNOWN
Conditions: Recurrent Pregnancy Loss
Interventions: BIOLOGICAL: Mesenchymal stem cells capable of differentiation in the endometrial-decidual direction|OTHER: Standard treatment according to the clinical protocols
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: DRIVESHAFT: Darunavir/Ritonavir In HIV-infected Virologically-suppressed Experienced Subjects
Status: COMPLETED
Conditions: HIV
Interventions: DRUG: Twice-daily combination Darunavir and ritonavir|DRUG: Once-daily combination Darunavir and ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase III Study to Evaluate the Efficacy and Safety of Intravenous Infusion of Nemonoxacin in Treating CAP
Status: COMPLETED
Conditions: Community-acquired Pneumonia
Interventions: DRUG: Nemonoxacin|DRUG: Levofloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Emollient Performance of Doublebase Once in the Treatment of Atopic Eczema
Status: NOT_YET_RECRUITING
Conditions: Atopic Eczema
Interventions: DEVICE: Doublebase Once
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Comparison of Two Silicone Hydrogel Toric Lenses in the US
Status: COMPLETED
Conditions: Astigmatism
Interventions: DEVICE: Lotrafilcon B contact lens|DEVICE: Comfilcon A contact lens
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Prevalence and Trends of Antimicrobial Resistance of Helicobacter Pylori in Korea
Status: RECRUITING
Conditions: Helicobacter Pylori Infection|Helicobacter Pylori Associated Gastrointestinal Disease|Helicobacter Pylori Infection, Susceptibility to|Helicobacter Pylori 23S rRNA Clarithromycin Resistance Mutation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Probiotics to Promote Intestinal Health
Status: COMPLETED
Conditions: Communicable Diseases|Infection|Anti-Infective Agents|Therapeutic Uses|Pharmacologic Actions
Interventions: DIETARY_SUPPLEMENT: Probiotic|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: CytoREductive prostAtectomy for Poly-metastatic Hormone sensiTIVE Prostate Cancer
Status: RECRUITING
Conditions: Prostate Cancer
Interventions: DRUG: Systemic Chemohormonal Therapy|DRUG: Systemic Hormonal Therapy|PROCEDURE: Cytoreductive Prostatectomy|PROCEDURE: Postoperative Adjuvant Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevention of PTSD III: Neurocognitive Training of Emotional Regulation
Status: COMPLETED
Conditions: Post Traumatic Stress Disorder|Major Depression|Anxiety Disorders
Interventions: PROCEDURE: Neurocognitive retraining Web Based Intervention|OTHER: Control, web-based tasks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Active Specific Immunotherapy for Follicular Lymphomas With Tumor-Derived Immunoglobulin Idiotype Antigen Vaccines
Status: COMPLETED
Conditions: B Cell Lymphoma|Follicular Lymphoma|Lymphoma
Interventions: DRUG: Id-KLH Vaccine|DRUG: GM-CSF
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Comparison of Wash Wipes and Standard Care in the Prevention of Incontinence-associated Dermatitis in Elderly
Status: TERMINATED
Conditions: Irritant Contact Dermatitis Due to Incontinence|Diaper Rash|Pressure Ulcer|Incontinence-associated Dermatitis
Interventions: OTHER: Wash wipes (3M)|OTHER: water and pH neutral soap
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Performance of Fanfilcon A Toric Lenses After at Least One Month Wearing Enfilcon A Toric Lenses
Status: COMPLETED
Conditions: Astigmatism
Interventions: DEVICE: fanfilcon A
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Open Label Trial of Intravenous Administration of MVA-BN-Brachyury Vaccine in Patients With Advanced Cancer
Status: COMPLETED
Conditions: Solid Metastatic Tumor
Interventions: BIOLOGICAL: MVA-BN-Brachyury
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Supporting the Wellness of Ontario Physicians During COVID-19
Status: COMPLETED
Conditions: Mental Health Wellness 1|Anxiety|Happiness
Interventions: OTHER: Remote SMS (short message service, also known as "text message") delivery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: OTHER
Clinical trial: A Study on Toripalimab Plus Nab-Paclitaxel With or Without Cisplatin as First-line Treatment of Urothelial Carcinoma
Status: UNKNOWN
Conditions: Urothelial Carcinoma
Interventions: DRUG: Toripalimab plus Nab-Paclitaxel +/- cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Magnetic Tape Over Ankle Dorsiflexion in Patients With Low Back Pain
Status: WITHDRAWN
Conditions: Low Back Pain
Interventions: DEVICE: Magnetic Tape®|DEVICE: Kinesiology Tape
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cinacalcet for Fibroblast Growth Factor 23 (FGF23)-Mediated Hypophosphatemia (Hypophosphatemic Rickets)
Status: TERMINATED
Conditions: Osteomalacia
Interventions: DRUG: Osteomalacia
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of [14C]-LOXO-783 in Healthy Adult Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: [¹⁴C]-LOXO-783|DRUG: LOXO-783|DRUG: [¹⁴C]-LOXO-783
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Radiofrequency and Chemical Neurolysis of Thoracic Splanchnic Nerve for Abdominal Cancer Pain
Status: UNKNOWN
Conditions: Abdominal Cancer
Interventions: DEVICE: Radiofrequency generator device|DRUG: Lidocaine|DEVICE: C arm fluoroscopic device|DRUG: Ethyl alcohol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Low Dose Decitabine + Interferon Alfa-2b in Advanced Renal Cell Carcinoma
Status: TERMINATED
Conditions: Renal Cell Carcinoma
Interventions: DRUG: Decitabine|DRUG: Interferon Alfa-2b
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of CoolSculpt Combining Venus Legacy Technology for Enhanced Results in Fat Reduction & Laxity of the Flanks
Status: COMPLETED
Conditions: Adipose Tissue
Interventions: DEVICE: multipolar RF, varipulse|DEVICE: cryolipolysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Family-based Intervention to Improve Pap Test Screening Among Under-screened Chinese American Immigrant Women
Status: UNKNOWN
Conditions: Cervical Cancer|Healthy Women
Interventions: BEHAVIORAL: family-based intervention|BEHAVIORAL: Participant only intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Effect of Gut Microbiome Intervention on Aging Via Oral FMT
Status: NOT_YET_RECRUITING
Conditions: Aging|Frailty
Interventions: BIOLOGICAL: FMT capsules|OTHER: Placebo capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT