pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Personalized Neoantigen Cancer Vaccine + Pembrolizumab After Rituximab for Follicular Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Follicular Lymphoma
Interventions: DRUG: Rituximab|BIOLOGICAL: Neo Vax|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With Heart Failure and Impaired Kidney Function
Status: RECRUITING
Conditions: Heart Failure and Impaired Kidney Function
Interventions: DRUG: balcinrenone/dapagliflozin 15 mg/10 mg and matching placebo for dapagliflozin 10 mg|DRUG: balcinrenone/dapagliflozin 40 mg/10 mg and matching placebo for dapagliflozin 10 mg|DRUG: dapagliflozin 10 mg and matching placebo for balcinrenone/dapagliflozin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Safety, Pharmacokinetics and Pharmacodynamics Study, Assessing Multiple LNP023 Doses in Adult Patients With Paroxysmal Nocturnal Hemoglobinuria
Status: COMPLETED
Conditions: Paroxysmal Nocturnal Hemoglobinuria
Interventions: DRUG: LNP023
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Three Months of Weekly Rifapentine and Isoniazid for M. Tuberculosis Infection
Status: COMPLETED
Conditions: Tuberculosis
Interventions: DRUG: RPT + INH once weekly for 3 months given by DOT|DRUG: Isoniazid (INH) daily for 9 months
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Can Acupuncture be Used as Preparation for Induction of Labour
Status: COMPLETED
Conditions: Pregnancy Overdue - Week 41+6
Interventions: DEVICE: acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of Dasatinib Plus Ixabepilone in 2nd or 3rd Line Metastatic Breast Cancer
Status: COMPLETED
Conditions: Metastatic Breast Cancer
Interventions: DRUG: Dasatinib|DRUG: Ixabepilone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of a Dietary Supplement on Hair Growth and Hair Health in Female With Acute Telogen Effluvium
Status: NOT_YET_RECRUITING
Conditions: Telogen Effluvium|Healthy
Interventions: DIETARY_SUPPLEMENT: An oral formulation of green tea extract, bamboo shoot extract and selenium-enriched yeast|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Atezolizumab in Participants With Locally Advanced or Metastatic Urothelial Bladder Cancer (Cohort 2)
Status: COMPLETED
Conditions: Bladder Cancer
Interventions: DRUG: Atezolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Short Incubation Methylaminolevulinate Photodynamic Therapy Without Occlusion
Status: COMPLETED
Conditions: Actinic Keratosis
Interventions: DRUG: Methylaminolevulinate (Metvix, Metvixia)|DEVICE: Photodynamic Therapy (Aktilite)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Esomeprazole 20mg qd vs Ranitidine 150mg Bid in Patients With an NSAID-induced Gastric Ulcer
Status: COMPLETED
Conditions: Gastric Ulcer
Interventions: DRUG: Esomeprazole|DRUG: Ranitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Recombinant Adeno-Associated Virus Acid Alpha-Glucosidase to Treat Pompe Disease
Status: COMPLETED
Conditions: Pompe Disease
Interventions: DRUG: rAAV1-CMV-GAA (study agent) Administration|OTHER: RMST
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Supporting Laypeople Addressing Prehospital Hemorrhage Study
Status: COMPLETED
Conditions: Hemorrhage|Laceration
Interventions: BEHAVIORAL: Audio kit|BEHAVIORAL: Instructional flashcard|BEHAVIORAL: In-person training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of JNJ-63723283, an Anti-programmed Death-1 Monoclonal Antibody, Administered in Combination With Daratumumab, Compared With Daratumumab Alone in Participants With Relapsed or Refractory Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Daratumumab|DRUG: JNJ-63723283
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Study of TG02 Citrate in Patients With Chronic Lymphocytic Leukemia and Small Lymphocytic Lymphoma
Status: COMPLETED
Conditions: Chronic Lymphocytic Leukemia|Small Lymphocytic Lymphoma
Interventions: DRUG: TG02 citrate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Usability and Performance Evaluation of the AutoLap System - a Feasibility Study
Status: COMPLETED
Conditions: General Laparoscopic Surgery Candidate|Bariatric Laparoscopic Surgery Candidate
Interventions: DEVICE: AutoLap
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Potential for Metformin to Improve Tumor Oxygenation in Locally Advanced Cervix Cancer: A Phase II Randomized Trial
Status: COMPLETED
Conditions: Uterine Cervical Neoplasms|Squamous Cell Carcinoma|Adenocarcinoma|Carcinoma, Adenosquamous
Interventions: DRUG: Metformin|DRUG: Cisplatin|DRUG: FAZA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Effects of a Formula With Modified Protein Levels and Fat Blend in Preterm Infants
Status: COMPLETED
Conditions: Infant, Premature, Nutrition
Interventions: OTHER: Standard formula for preterm infants|OTHER: Formula with higher protein and new fat blend for preterm infants
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Comparison of Sedation/Analgesia: Midazolam/Morphine Vs Propofol/Remifentanil
Status: TERMINATED
Conditions: Shoulder Dislocation
Interventions: DRUG: Sedation with propofol and remifentanil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial of Traffic Light Labeling With Behavioral Nudges and a Healthy Recipe Database to Increase Selection of Healthier Foods in Client-choice Food Pantries
Status: TERMINATED
Conditions: Food Selection
Interventions: BEHAVIORAL: Healthy Pantry Program|OTHER: Waitlist Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Bone-borne Palatal Expander With Corticotomy for Cleft Palate Patients
Status: UNKNOWN
Conditions: Cleft Palate
Interventions: OTHER: Use of bone-borne palatal expander & maxillary osteotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Gadobutrol 1.0 Molar (Gadavist) in Patients for Central Nervous System (CNS) Imaging
Status: COMPLETED
Conditions: Diagnostic Imaging|Central Nervous System Diseases
Interventions: DRUG: Gadobutrol (Gadavist, Gadovist, BAY86-4875)|DRUG: Gadoteridol (ProHance)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Clinical Study to Evaluate the Blood Triglyceride Decreasing Effect and Safety of Korean Post-Fermented Tea Extracts
Status: COMPLETED
Conditions: Triglycerides High
Interventions: DIETARY_SUPPLEMENT: Heukcha Extracts|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: M9241 in Combination With Docetaxel in Adults With Metastatic Castration Sensitive and Castration Resistant Prostate Cancer
Status: RECRUITING
Conditions: Cancer Of Prostate|Prostate Neoplasms
Interventions: DRUG: ADT|DRUG: Prednisone|DRUG: M7824|DRUG: Docetaxel|DRUG: M9241
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Medical Nutrition Therapy or Standard Care in Treating Patients With Lung Cancer, Pancreatic Cancer, or Stage III or Stage IV Prostate Cancer
Status: TERMINATED
Conditions: Lung Cancer|Malnutrition|Pancreatic Cancer|Prostate Cancer|Weight Changes
Interventions: BEHAVIORAL: Medical nutrition therapy|BEHAVIORAL: Standard Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study to Evaluate the Efficacy and Safety of ZL-3101 in Subjects With Subacute Eczema
Status: COMPLETED
Conditions: Eczema
Interventions: DRUG: ZL-3101|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Understanding Factors That Influence Electronic Cigarette Nicotine Delivery Through PET Imaging of Beta-2 Nicotinic Acetylcholine Receptors
Status: WITHDRAWN
Conditions: Electronic Cigarette Use
Interventions: DRUG: Low strength nicotine e-liquid|DRUG: High strength nicotine e-liquid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Pediatric Intensive Care Units (ICUs) at Emory-Children's Center Glycemic Control: The PedETrol Trial
Status: COMPLETED
Conditions: Pediatric Patient (1m-21y)|ICU Admission|Hyperglycemia
Interventions: OTHER: Active Glycemic Control Strict (80-140mg/dL) vs. Conservative (190-220mg/dL) (with or without Continuous Glucose Monitoring)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare Two Surgical Procedures in Individuals With BRCA1 Mutations to Assess Reduced Risk of Ovarian Cancer
Status: RECRUITING
Conditions: Ovarian Carcinoma
Interventions: PROCEDURE: Bilateral Salpingectomy|PROCEDURE: Bilateral Salpingectomy with Oophorectomy|PROCEDURE: Biospecimen Collection|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration|PROCEDURE: Transvaginal Ultrasound|PROCEDURE: Ultrasound Imaging
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Dexemedetomidine on Shivering Cesarean Section Under Spinal Anesthesia A Randomized Clinical Trial
Status: NOT_YET_RECRUITING
Conditions: Postoperative Shivering
Interventions: OTHER: giving dexemedetomidine 12 microgram Iv dripping|OTHER: Dexamethsone IV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Chemoradiotherapy With Gemcitabine/S-1 vs Gemcitabine/S-1 for Locally Advanced Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DRUG: Drug: gemcitabine, S-1|DRUG: gemcitabine, S-1, radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Imatinib in Chronic Myelogenous Patients Older Than 70 Years
Status: COMPLETED
Conditions: Chronic Myeloid Leukemia
Interventions: DRUG: Imatinib mesylate 400 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessing NOS Uptake With PET Imaging in Lung Inflammation
Status: COMPLETED
Conditions: Lung Inflammation
Interventions: DRUG: Endotoxin (E. coli O:113, Reference Endotoxin)|DRUG: [18F](+/-)NOS
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Influence of an Anti-osteoporotic Drug on Healing After Surgical Repair of Chronic Rotator Cuff Lesions of the Shoulder
Status: RECRUITING
Conditions: Orthopedics|Traumatology
Interventions: DRUG: Intravenous Infusion of Aclasta®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Childhood Absence Epilepsy Rx PK-PD-Pharmacogenetics Study
Status: COMPLETED
Conditions: Childhood Absence Epilepsy|Petit Mal Epilepsy|Epilepsy|Seizures
Interventions: DRUG: Ethosuximide|DRUG: Lamotrigine|DRUG: Valproic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Cervical Rehabilitation Program on Neck Pain, ROM and Disability After Thyroidectomy.
Status: COMPLETED
Conditions: Thyroiditis, Postpartum
Interventions: OTHER: cervical rehabilitation program|OTHER: control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Weekly Versus Three-week Chemoradiation in Patients With Advanced Cervical Cancer
Status: COMPLETED
Conditions: Cervical Cancers
Interventions: RADIATION: radiation|DRUG: weekly cisplatin|DRUG: tri-weekly cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Trastuzumab Emtansine (T-DM1) Sequentially With Anthracycline-based Chemotherapy, as Adjuvant or Neoadjuvant Therapy for Patients With Early Stage Herceptin (HER)2-positive Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Trastuzumab emtansine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Restrictive Versus Standard Fluid Regime in Elective Minilaparotomy Abdominal Aortic Aneurysm Repair
Status: COMPLETED
Conditions: Abdominal Aortic Aneurysm > 5.5 cm Effect of a Restricted Intravenous Fluid Regime on Complications and Hospital Stay After the Minilaparotomy AAA Repair.
Interventions: PROCEDURE: Restrictive VS Standard Fluid Regime|DRUG: Drag: Crystalloids and Colloids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Passive Stretching in Peripheral Arterial Disease Patients
Status: RECRUITING
Conditions: Peripheral Arterial Disease|Walking, Difficulty|Inflammation
Interventions: DEVICE: Calf Plantar flexion|DIETARY_SUPPLEMENT: Dietary nitrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of the Use of Desensitizing Dentifrices Based on Nanocrystals of Hydroxyapatite / 5% Potassium Nitrate / 1450ppm Sodium Monofluorophosphate and Potassium Nitrate 5% / 1426ppm Sodium Floride in the Treatment of Dentine Hypersensitivity. Test Randomized Clinical
Status: UNKNOWN
Conditions: Hypersensitivity Dentin
Interventions: OTHER: DEENSIBILIZING TOOTHPASTE BASED ON NANOCRISTALS OF HYDROXIAPATITA / 5% POTASSIC NITRATE / SODIUM MONOFluORPHOSPHATE 1450 PARTS PER MILLION|OTHER: 5% POTASSIC NITRATE / SODIUM FLUORIDE 1426 PARTS PER MILLION TOOTHPASTE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Left Atrial Appendage Closure Versus Antithrombotic Therapy in Patients With Atrial Fibrillation Undergoing Drug-Eluting Stent Implantation Due to Complex Coronary Artery Disease
Status: TERMINATED
Conditions: Atrial Fibrillation|Coronary Artery Disease
Interventions: DRUG: Dabigatrain plus aspirin|DRUG: Dabigatrain plus clopidogrel|DEVICE: Amplazter Cardiac Plug (ACP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lean Body Weight-adjusted Rocuronium Dose and Intubation Conditions
Status: COMPLETED
Conditions: Body Weight Changes|Rocuronium|Intubation Conditions
Interventions: PROCEDURE: he patients who are administered rocuronium according to LBW were categorized as "LBW", and The group number for those administer according to TBW was categorized as "K".
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects Of Dry Needling On Sternocleidomastoid Muscle For Pain And Disability In Migraine
Status: COMPLETED
Conditions: Migraine
Interventions: OTHER: Dry Needling|OTHER: Placebo Dry Needling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pazopanib in Molecularly Selected Patients With Advanced NSCLC
Status: TERMINATED
Conditions: Carcinoma, Non-Small Cell Lung|Non-Small Cell Lung Cancer|Nonsmall Cell Lung Cancer
Interventions: DRUG: Pazopanib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Developing an Optimal Gemcitabine Based Regimen to Treat Elderly Patients With Advanced Non-Small Cell Carcinoma
Status: UNKNOWN
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: Gemcitabine, UFT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability of Low Dose Primaquine
Status: COMPLETED
Conditions: Malaria, Falciparum|G6PD Deficiency
Interventions: DRUG: Dihydroartemisinin piperaquine (DHA PP)|DRUG: Primaquine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Basal (Fasting) Glycemic Control in Type 1 Diabetic Patients With CSII Achieved by the Circadian Slide Ruler Scale or Flat Basal Rate
Status: COMPLETED
Conditions: Diabetes Mellitus Type 1
Interventions: DEVICE: Accu-Chek Spirit Insulin Pump|DEVICE: Accu-Chek Spirit Insulin Pump
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Phase 3 Study to Determine if RTB101 Prevents Clinically Symptomatic Respiratory Illness in the Elderly
Status: COMPLETED
Conditions: Respiratory Tract Infections
Interventions: DRUG: Dactolisib|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Barbed Reposition Pharyngoplasty in Patients Complaining of Unilevel Palatal Snoring
Status: ACTIVE_NOT_RECRUITING
Conditions: Snoring|Sleep-Disordered Breathing
Interventions: PROCEDURE: Barbed reposition pharyngoplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Database of Colorectal Robotic Surgery
Status: ACTIVE_NOT_RECRUITING
Conditions: Crohn Disease|Polyposis|Ulcerative Colitis|Diverticulitis|Colorectal Tumor|Rectal Prolapse|Benign Colorectal Tumor
Interventions: OTHER: Clinical database
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: An Phase 1 Study to Evaluate the Pharmacokinetic (PK) Profile of FDL169 New Formulations in Healthy Subjects
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: FDL169
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Beating the Blues for Your Heart
Status: COMPLETED
Conditions: Depression|Depressive Symptoms|Cardiovascular Disease (CVD)|Coronary Artery Disease (CAD)|Heart Disease
Interventions: BEHAVIORAL: Beating the Blues (BtB)|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Effect of Diltiazem on the Pharmacokinetics (PK) of BMS-986141 in Healthy Subjects
Status: COMPLETED
Conditions: Ischemic Stroke
Interventions: DRUG: BMS-986141|DRUG: Dilitazem
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Relative Bioavailability of Dabigatran and Digoxin in Healthy Male and Female Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Dabigatran etexilate|DRUG: Digoxin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radiation Therapy or Surgery in Treating Patients With Previously Untreated Vulva Cancer With Positive Groin Lymph Nodes
Status: COMPLETED
Conditions: Vulvar Cancer
Interventions: PROCEDURE: regional lymph node dissection|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: A Double-blind, Randomised, Parallel Group,Comparative Study With Rose-hip Liquid and Placebo Given to Healthy Volunteers in the Winter Season Aiming to Evaluate the Occurences of Flu and Catching a Cold
Status: COMPLETED
Conditions: Flu|Common Cold
Interventions: DIETARY_SUPPLEMENT: Rose hip Liquid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Paclitaxel and Intraperitoneal Carboplatin Followed by Radiation Therapy in Treating Patients With Stage IIIC-IV Uterine Cancer
Status: TERMINATED
Conditions: Endometrial Serous Adenocarcinoma|Stage IIIA Uterine Corpus Cancer|Stage IIIB Uterine Corpus Cancer|Stage IIIC1 Uterine Corpus Cancer|Stage IIIC2 Uterine Corpus Cancer|Stage IVA Uterine Corpus Cancer|Stage IVB Uterine Corpus Cancer
Interventions: DRUG: Paclitaxel|DRUG: Carboplatin|RADIATION: 3-Dimensional Conformal Radiation Therapy|RADIATION: Intensity-Modulated Radiation Therapy|OTHER: Quality-of-Life Assessment|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aripiprazole as an Adjunct to Atypical Antipsychotics for Weight Reduction and Improvement in Metabolic Profile
Status: COMPLETED
Conditions: Antipsychotics Weight Gain
Interventions: DRUG: Aripiprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CLCNKA (Ka Renal Chloride Channel[ClC-Ka]) Polymorphism Effects on Hypertrophy Regression
Status: WITHDRAWN
Conditions: Hypertension
Interventions: DRUG: Eplerenone|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Preoperative Short Course Radiotherapy With Chemotherapy and Camerelizumab in Locally Advanced Rectal Cancer
Status: UNKNOWN
Conditions: Rectal Cancer|Radiotherapy|Immunotherapy
Interventions: DRUG: Camrelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Effects on Asthma Control of Rabeprazole Given Twice Daily in Subjects With Asthma.
Status: COMPLETED
Conditions: Asthma|Gastroesophageal Reflux Disease
Interventions: DRUG: rabeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Role of Mesenchymal Stem Cells in Fat Grafting
Status: UNKNOWN
Conditions: Romberg's Disease|Craniofacial Microsomia|Lipodystrophy|Mixed Connective Tissue Disease
Interventions: PROCEDURE: Fat graft enriched with ex vivo expanded stem cells|PROCEDURE: Fat graft not enriched with ex vivo expanded stem cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Anlotinib Hydrochloride Combined With Sintilimab Injection in the Treatment of Advanced Hepatocellular Carcinoma (HCC)
Status: UNKNOWN
Conditions: Advanced Hepatocellular Carcinoma
Interventions: DRUG: Anlotinib and Sintilimab injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Computerized Working Memory Training in Very-low-birth-weight Children at Preschool Age
Status: COMPLETED
Conditions: Infant, Very Low Birth Weight
Interventions: BEHAVIORAL: Cogmed JM working memory training|BEHAVIORAL: Cogmed JM working memory training after waiting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Grandi Byen: Supporting Child Growth and Development Through Integrated, Responsive Parenting, Nutrition and Hygiene
Status: RECRUITING
Conditions: Malnutrition, Child|Development, Child|Parenting
Interventions: DIETARY_SUPPLEMENT: Nutrition Intervention|BEHAVIORAL: Grandi Byen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Mediterranean Enriched Diet for Tackling Youth Obesity
Status: ACTIVE_NOT_RECRUITING
Conditions: Obesity, Adolescent|Lifestyle, Healthy|Diet, Healthy|Cardiovascular Risk Factor
Interventions: OTHER: Diet and behavioural intervention|OTHER: Diet and behavioural intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety/Proof of Concept Study of Oral QLT091001 in Subjects With Leber Congenital Amaurosis (LCA) or Retinitis Pigmentosa (RP) Due to Retinal Pigment Epithelial 65 Protein (RPE65) or Lecithin:Retinol Acyltransferase (LRAT) Mutations
Status: COMPLETED
Conditions: LCA (Leber Congenital Amaurosis)|RP (Retinitis Pigmentosa)
Interventions: DRUG: QLT091001
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Adverse Events, and Change in Disease Activity, When Intravenously (IV) Infused With Livmoniplimab in Combination With IV Infused Budigalimab in Adult Participants With Hepatocellular Carcinoma (HCC)
Status: RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Budigalimab|DRUG: Livmoniplimab|DRUG: Lenvatinib|DRUG: Sorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PROMOTE: Identifying Predictive Markers of Response for Genitourinary Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Cancer|Advanced Renal Cell Carcinoma|Advanced Urothelial Carcinoma|Genitourinary Cancer
Interventions: OTHER: Systemic therapy|DEVICE: StrataNGS
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of Cardiopulmonary Exercise Testing in Women Who Have HER2-Positive Breast Cancer With Mild Cardiotoxicity
Status: RECRUITING
Conditions: Breast Cancer|HER2-positive Breast Cancer|HER2-positive Metastatic Breast Cancer|Breast Cancer Stage I|Breast Cancer Stage II|Breast Cancer Stage III|Breast Cancer Stage IV|Cardiotoxicity
Interventions: DIAGNOSTIC_TEST: Cardiopulmonary Exercise Test|DIAGNOSTIC_TEST: Echocardiogram|DIAGNOSTIC_TEST: Echocardiography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Naproxen on Tooth Sensitivity Caused by In-office Bleaching
Status: COMPLETED
Conditions: Toothache|Tooth Bleaching
Interventions: DRUG: Naproxen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Massage and Musıc Therapy on Birth Pain, Posttravmatic Comfort and Posttraumatic Development
Status: COMPLETED
Conditions: Labor Pain|Posttraumatic Growth
Interventions: BEHAVIORAL: Massage group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Phase 1 Study of TE-8214 Solution in Healthy Volunteers
Status: NOT_YET_RECRUITING
Conditions: Acromegaly
Interventions: DRUG: TE-8214 - SAD|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Impact on Ovarian Reserve of Diode Laser vs Bipolar Coagulation of Endometriomas
Status: COMPLETED
Conditions: Ovarian Endometrioma
Interventions: PROCEDURE: Diode laser coagulation|PROCEDURE: Bipolar coagulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability of Inhaled CHF 6001 in Healthy Volunteers (HV)
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: DRUG: CHF 6001 SD or placebo|DRUG: CHF 6001 MD or placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fludarabine and Cyclophosphamide Followed by Peripheral Stem Cell Transplant in Treating Patients With Leukemia or Lymphoma
Status: COMPLETED
Conditions: Leukemia|Lymphoma
Interventions: DRUG: fludarabine phosphate|DRUG: Cyclophosphamide|BIOLOGICAL: PBSC|DRUG: G-CSF|BIOLOGICAL: Donor lymphocytes
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Repeat Stereotactic Radiation in Patients With Intraprostatic Tumor Recurrence
Status: RECRUITING
Conditions: Local Recurrence of Malignant Tumor of Prostate
Interventions: RADIATION: Stereotactic Body Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Implementing and Testing a Cardiovascular Assessment Screening Program (CASP)
Status: COMPLETED
Conditions: Cardiovascular Risk Factor|Smoking|Diabetes Mellitus|Dyslipidemias|Hypertension|Physical Activity|Stress, Psychological
Interventions: BEHAVIORAL: Cardiovascular Assessment Screening Program (CASP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Evaluation of Allium Ampeloprasum Spp.Iranicum Cream Effect for the Management of Hemorrhoids Symptoms
Status: UNKNOWN
Conditions: Hemorrhoids
Interventions: DRUG: Leek topical cream|DRUG: placebo topical cream|DRUG: Anti-hemorrhoid topical cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Clinical Study of Apatinib Plus S1 for Patients With Advanced Non-squamous Head and Neck Cancer
Status: UNKNOWN
Conditions: Head and Neck Neoplasms
Interventions: DRUG: Apatinib|DRUG: S1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fluid Responsiveness: SVV vs esSVV in Mechanically Ventilated and Spontaneously Breathing Patients
Status: COMPLETED
Conditions: Hemodynamic Instability|Postoperative Complications
Interventions: DEVICE: estimated stroke volume variation (esSVV, Nihon Kohden, Japan)|DIAGNOSTIC_TEST: Assessment of fluid responsiveness in mechanically ventilated patients after OPCAB|DIAGNOSTIC_TEST: Assessment of fluid responsiveness in spontaneously breathing patients at 18 hrs of the postoperative period
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Preventing Microalbuminuria in Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes
Interventions: DRUG: Benazepril|DRUG: Valsartan|DRUG: Benazepril/Valsartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mindfulness-Based Relapse Prevention for Opioid and Alcohol Use Disorders
Status: COMPLETED
Conditions: Opioid-use Disorder|Opioid Abuse, in Remission|Alcohol Use Disorder|Alcohol Use Disorder, in Remission
Interventions: BEHAVIORAL: Mindfulness Based Relapse Prevention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Randomized Double Blinded Study to Examine the Use of N-acetyl Cysteine for the Prevention and Treatment of HAAF in Patients With Type 1 Diabetes
Status: COMPLETED
Conditions: Type 1 Diabetes|Hypoglycemia Unawareness
Interventions: DRUG: N-acetyl cysteine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Anti-psychotic Medication (New Use) Weight Loss Study
Status: WITHDRAWN
Conditions: Obesity
Interventions: DIETARY_SUPPLEMENT: IHBG-10|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Testing Home-based Exercise Strategies in Underserved Minority Cancer Patients Undergoing Chemotherapy: the THRIVE Study
Status: RECRUITING
Conditions: Breast Cancer|Colorectal Cancer|Prostate Cancer
Interventions: BEHAVIORAL: Supervised Home-Based Exercise|BEHAVIORAL: Unsupervised Home-Based Exercise|BEHAVIORAL: Attention Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Intrapartum Vulval and Perineal Cleansing Using Chlorhexidine Versus Normal Saline
Status: NOT_YET_RECRUITING
Conditions: Maternal Infection During Pregnancy
Interventions: OTHER: Perineal cleansing using chlorhexidine acetate solution|OTHER: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Archwire Gauge on the Rate of Canine Retraction
Status: COMPLETED
Conditions: Canine Retraction
Interventions: OTHER: st.st 0.019×0.025" wire|OTHER: st.st 0.016×0.022" wire|OTHER: st.st 0.017×0.025" wire
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Optimizing Integrated PMTCT Services in Rural North-Central Nigeria
Status: COMPLETED
Conditions: Suspected Damage to Fetus From Viral Disease in the Mother|HIV
Interventions: OTHER: Task-shifting to lower-cadre providers at PMTCT sites|OTHER: POC CD4+ cell count testing|OTHER: integrated mother-infant care|OTHER: Prominent role for influential family members (male partners) in collaboration with CHWs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Combination Topical Therapy for Treatment of Scalp Actinic Keratoses
Status: TERMINATED
Conditions: Actinic Keratoses
Interventions: DRUG: Calcipotriene 0.005% Foam|DRUG: Efudex 5% Topical Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long Term Evaluation of Clinical and Radiologic Results on Femoro-patellar Joint After High Tibial Osteotomy
Status: RECRUITING
Conditions: Knee Osteoarthritis|Deformity Knee
Interventions: DIAGNOSTIC_TEST: X-rays: load bearing inferior limbs, lateral knee, axial patella
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Perioperative Chemotherapy VS Postoperative Chemotherapy for the Treatment of Colon Cancer With Resectable Liver Metastasis
Status: UNKNOWN
Conditions: Colon Cancer
Interventions: DRUG: Peri-operative chemotherapy|DRUG: postoperative chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bowel Preparation in Elective Pediatric Colorectal Surgery
Status: UNKNOWN
Conditions: Colostomy|Hirschsprung Disease - Pull Through|Necrotizing Enterocolitis|Inflammatory Bowel Diseases|Meconium Ileus|Bowel Obstruction|Elective Surgery
Interventions: DRUG: Senna|DRUG: Sodium Picosulfate, Magnesium Oxide and Citric Acid|DRUG: Metronidazole Oral|DRUG: Neomycin|DRUG: Cefazolin|DRUG: Metronidazole|OTHER: Nil per os|OTHER: Clear fluids the day before surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Anti-oxidant, Anti-aging and Wellbeing Effects of a Novel Nutraceutical Formulation (HealthSpan)
Status: COMPLETED
Conditions: Aging|Well Aging|Oxidative Stress
Interventions: DIETARY_SUPPLEMENT: HealthSpan|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Phase 1b Trial of ATRC-101 in Adults With Advanced Solid Malignancies
Status: TERMINATED
Conditions: Breast Cancer|Colorectal Cancer|Ovarian Cancer|Non-Small Cell Lung Cancer|Acral Lentiginous Melanoma|Head and Neck Squamous Cell Carcinoma|Hepatocellular Carcinoma|Esophageal Squamous Cell Carcinoma|Urothelial Carcinoma|DMMR Colorectal Cancer|MSI-H Colorectal Cancer|Melanoma|Platinum-Resistant Primary Peritoneal Carcinoma|Platinum-Resistant Fallopian Tube Carcinoma|Platinum-Resistant Epithelial Ovarian Cancer|Triple Negative Breast Cancer
Interventions: BIOLOGICAL: ATRC-101|BIOLOGICAL: Pembrolizumab|DRUG: Pegylated liposomal doxorubicin (PLD)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hypnotic Medications and Memory: Effect of Drug Exposure During the Night
Status: COMPLETED
Conditions: Sleep|Memory
Interventions: DRUG: zaleplon|DRUG: zolpidem extended release|DRUG: bedtime placebo|DRUG: middle of the night placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Glucose-Lowering Effects and Safety of Adding 0.25 or 0.5 mg Duvie
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus|Inadequate Glucose Control
Interventions: DRUG: duvie
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of UTTR1147A Compared With Placebo and With Vedolizumab in Participants With Moderate to Severe Ulcerative Colitis (UC)
Status: COMPLETED
Conditions: Ulcerative Colitis
Interventions: DRUG: UTTR1147A|DRUG: UTTR1147A Placebo|DRUG: Vedolizumab|DRUG: Vedolizumab Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Cell Therapy to Treat Chronic Obstructive Pulmonary Disease
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease|Pulmonary Emphysema
Interventions: DRUG: Stem cells stimulation|PROCEDURE: stem cells collection|GENETIC: stem cells infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Nordic Walking on Gait-asymmetry Patterns in Children With Hemiparesis
Status: NOT_YET_RECRUITING
Conditions: Cerebral Palsy
Interventions: OTHER: designed physical therapy program|OTHER: Nordic walking
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PMCF Study to Evaluate Performance and Safety of "Ocular Drops Based Upon Carmellose" Used to Relieve Dry Eye Symptoms
Status: COMPLETED
Conditions: Dry Eye|Dry Eye Disease|Kerato Conjunctivitis Sicca
Interventions: DEVICE: Carmellose eye drops
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Does Administration of Probiotics During Infancy Increase the Caries Risk of a Child
Status: WITHDRAWN
Conditions: Dental Caries
Interventions: DIETARY_SUPPLEMENT: Probiotics in infant milk formula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Use of Harmonic Scalpel to Decrease Lymphatic and Chest Tube Drainage After Lymph Node Dissection With Lobectomy.
Status: RECRUITING
Conditions: Lung Cancer
Interventions: DEVICE: Harmonic ACE23P Scalpel|DEVICE: Electrocautery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sugammadex and Cognitive Function
Status: COMPLETED
Conditions: Post Operative Cognitive Dysfunction
Interventions: DRUG: Sugammadex|DRUG: Neostigmine/atropine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: 18F-FDG PET and Osimertinib in Evaluating Glucose Utilization in Patients With EGFR Activated Recurrent Glioblastoma
Status: ACTIVE_NOT_RECRUITING
Conditions: EGFR Gene Amplification|EGFR Gene Mutation|Glioblastoma|Recurrent Glioblastoma|Supratentorial Glioblastoma|TP53 wt Allele
Interventions: OTHER: Fludeoxyglucose F-18|DRUG: Osimertinib|PROCEDURE: Positron Emission Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 2a RDEA3170 and Allopurinol Combination Study in Gout Subjects
Status: COMPLETED
Conditions: Gout
Interventions: DRUG: RDEA3170 2.5 mg|DRUG: allopurinol 300 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prostaglandin Inhibition and Immune Checkpoint Blockade in Melanoma
Status: COMPLETED
Conditions: Stage III Cutaneous Melanoma|Stage IIIA Cutaneous Melanoma|Stage IIIB Cutaneous Melanoma|Stage IIIC Cutaneous Melanoma|Stage IV Cutaneous Melanoma
Interventions: DRUG: Aspirin|BIOLOGICAL: Ipilimumab|OTHER: Laboratory Biomarker Analysis|BIOLOGICAL: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating Piezo-ICSI. - The EPI Study.
Status: SUSPENDED
Conditions: IVF|Infertility
Interventions: DEVICE: Piezo-ICSI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Open-Label Study of the Safety and Efficacy of Subcutaneous Recombinant Interferon-Gamma 1b (IFN-Gamma 1b) in Patients With Idiopathic Pulmonary Fibrosis (IPF)
Status: COMPLETED
Conditions: Lung Disease|Pulmonary Fibrosis
Interventions: DRUG: interferon-gamma 1b
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Safety and Efficacy of UC-MSCs in Pediatric Patients With Cerebral Palsy
Status: ACTIVE_NOT_RECRUITING
Conditions: Cerebral Palsy|Periventricular Leukomalacia
Interventions: BIOLOGICAL: UDI-001
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multiple-dose Escalation Clinical Study of VC005 Tablets in Healthy Subjects
Status: COMPLETED
Conditions: Inflammatory Bowel Diseases
Interventions: DRUG: VC005 tablets|DRUG: VC005 Placebo tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Self-myofascial Release Combined With Biofeedback and Electrical Stimulation for the Management of MFPP
Status: COMPLETED
Conditions: Myofascial Pelvic Pain
Interventions: PROCEDURE: BES-SMFR|PROCEDURE: BES
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ciNPT in Autologous Abdominal Tissue Breast Reconstruction
Status: NOT_YET_RECRUITING
Conditions: Breast Cancer
Interventions: PROCEDURE: DIEP Breast Reconstruction|DEVICE: ciNPT|OTHER: Conventional Tape Dressings
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study of CD19 Targeted CAR-T for Patients With CD19+ Lymphoma and Leukemia
Status: RECRUITING
Conditions: B Cell Leukemia|B Cell Lymphoma
Interventions: BIOLOGICAL: ICAR19 CAR-T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Investigator Initiated Trial to Evaluate the Safety and Feasibility of the DyNETIC-35 Stent for Iliac Lesions Via a Trans-radial Approach
Status: RECRUITING
Conditions: Peripheral Arterial Disease
Interventions: DEVICE: Dynetic-35 Peripheral Balloon-Expandable Stent System
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p