pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: DC Vaccine Therapy Combined With Cytokine-Induced Killer Cell in Treating
Status: NOT_YET_RECRUITING
Conditions: Renal Neoplasma
Interventions: BIOLOGICAL: DC-CIK|BIOLOGICAL: IL-2/IFN-α
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Kinematic Alignment Compared to Mechanical Alignment Techniques for Total Knee Replacement Surgery (KARMA)
Status: COMPLETED
Conditions: Osteo Arthritis Knee
Interventions: OTHER: Kinematic Alignment for total knee replacement surgery|OTHER: Mechanical Alignment for total knee replacement surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: CBT on Fatigue in Survivors of Hodgkin Lymphoma
Status: COMPLETED
Conditions: Hodgkin Lymphoma|Fatigue
Interventions: BEHAVIORAL: Cognitive Behavioral Therapy for Treating Fatigue
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Clinical Study on Autologous Stromal Vascular Fraction(SVF) Treatment for Refractory Benign Airway Stenosis and Respiratory Tract Fistula
Status: UNKNOWN
Conditions: Benign Airway Stenosis|Respiratory Tract Fistula
Interventions: PROCEDURE: Control group|PROCEDURE: SVF group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Can a Smartphone App That Includes a Chatbot-based Coaching and Incentives Increase Physical Activity in Healthy Adults?
Status: COMPLETED
Conditions: Physical Activity
Interventions: BEHAVIORAL: Self-regulation coaching|BEHAVIORAL: Planning|BEHAVIORAL: Financial Incentives|BEHAVIORAL: Charity Incentives
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Double-blind Randomised, Placebo-controlled Clinical Trial to Test Ambroxol Treatment in ALS
Status: RECRUITING
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DRUG: Ambroxol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Mouthrinses on the Microbiome of the Oral Cavity and GI Tract
Status: RECRUITING
Conditions: Oral Bacterial Infection|Oral Infection|Microbial Colonization|Viral Infection
Interventions: OTHER: Lumineux Oral Essentials rinse|OTHER: Listerine rinse
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Natural History Study of Children With Metachromatic Leukodystrophy
Status: TERMINATED
Conditions: Lipid Metabolism Disorders|Metachromatic Leukodystrophy (MLD)|Nervous System Diseases|Brain Diseases|Central Nervous System Diseases|Demyelinating Diseases|Metabolism, Inborn Errors|Genetic Diseases, Inborn|Sphingolipidoses|Hereditary Central Nervous System Demyelinating Diseases|Metabolic Inborn Brain Diseases|Lysosomal Storage Diseases|Metabolic Diseases|Sulfatidosis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Exploratory Efficacy of Kanglaite Injection in Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DRUG: Kanglaite Injection plus gemcitabine|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Multicenter Study of 5 vs 6 Weekly Fraction of RT in the Treatment of SCC of the Head and Neck
Status: COMPLETED
Conditions: Carcinoma, Squamous Cell
Interventions: RADIATION: 5 vs 6 weekly fraction of RT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Randomized Controlled Multicenter Trial of 4 Antiseptic Strategies for Prevention of Catheter Infection in Intensive Care Unit for Adults Patients
Status: COMPLETED
Conditions: Preventing Catheter Related Infection
Interventions: PROCEDURE: skin disinfection prior catheter insertion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Deep Brain Stimulation (DBS) Sedation
Status: TERMINATED
Conditions: Brain|Sedation
Interventions: DRUG: Remifentanil|DRUG: Propofol|DRUG: Dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of the Combination of Glumetinib and Docetaxel（Albumin Bound）Verse Docetaxel for the Treatment of MET-overexpressed Non-small Cell Lung Cancer
Status: NOT_YET_RECRUITING
Conditions: Locally Advanced/Recurrent or Distant Metastasized Non-small Cell Lung Cancer With MET Overexpression
Interventions: DRUG: Glumetinib tablets|DRUG: HB1801 (docetaxel, albumin-bound）|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Knee Brace and Biomechanical Footwear in the Treatment of Knee Osteoarthritis.
Status: COMPLETED
Conditions: Osteoarthritis,Knee
Interventions: OTHER: Home-based exercise|DEVICE: Knee brace|DEVICE: Biomechanical footwear device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Surveillance Study of Diseases Specified as Adverse Events of Special Interest, of Other Adverse Events Leading to Hospitalisation or Death, and of Meningitis in Children in Africa Prior to Implementation of the RTS,S/AS01E Candidate Vaccine
Status: COMPLETED
Conditions: Malaria|Malaria Vaccines
Interventions: PROCEDURE: Blood collection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: In Vivo Study of Sucrose and Liquid Oral Pediatric Medicines of Long-term Effect on Dental Biofilm pH
Status: COMPLETED
Conditions: Dental Biofilm pH
Interventions: OTHER: G1, G2 and G3|OTHER: G4 and G5
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: the Effect of Viewing Idealized Smile Images Versus Nature Images Via Social Media on Immediate Facial Satisfaction in Young Adults: a Randomized Controlled Trial.
Status: COMPLETED
Conditions: Facial Satisfaction
Interventions: BEHAVIORAL: facial dissatisfaction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: The STRETCH Study: Distensibility on Endothelial-Dependent Vasoreactivity in Subjects With Systolic Hypertension
Status: COMPLETED
Conditions: Cardiovascular Disease
Interventions: DRUG: ALT-711 (alagebrium chloride)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Therapeutic Effect of Surgical Debulking of Metastatic Lymph Nodes in Cervical Cancer Stage IIICr
Status: RECRUITING
Conditions: Cervical Cancer
Interventions: RADIATION: CCRT|PROCEDURE: Surgical debulking of bulky or multiple lymph nodes|RADIATION: CCRT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: (1,3)-β-D-glucan Based Diagnosis of Invasive Candida Infection in Sepsis
Status: COMPLETED
Conditions: Severe Sepsis|Septic Shock
Interventions: OTHER: Standard of care|OTHER: (1,3)-β-D-glucan guided therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Does the HPV Vaccine Cause the Same Response in Adolescent Kidney and Liver Transplant Patients as in Healthy Controls?
Status: COMPLETED
Conditions: Cervical Cancer|Hpv|Warts
Interventions: BIOLOGICAL: Quadrivalent HPV for types 6, 11, 16 and 18
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study to Evaluate Meningococcal Serogroups A,C,W-135,Y Conjugate Vaccine When Given as 1 Dose to Healthy Subjects Aged 18-25 Years
Status: COMPLETED
Conditions: Infections, Meningococcal
Interventions: BIOLOGICAL: Meningococcal (vaccine)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy Study of Bimatoprost in the Treatment of Women With Female Pattern Hair Loss
Status: COMPLETED
Conditions: Alopecia|Baldness
Interventions: DRUG: bimatoprost Formulation A|DRUG: bimatoprost Formulation B|DRUG: bimatoprost Formulation C|DRUG: bimatoprost vehicle solution|DRUG: minoxidil 2% solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mentholated Cream Containing Oxygenated Glycerol Triesters on Acute Pain of the Muscles and Joints
Status: COMPLETED
Conditions: Pain|Analgesics
Interventions: OTHER: Mentholated Cream|OTHER: Mentholated Cream with OGT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Tozorakimab in Patients Hospitalised for Viral Lung Infection Requiring Supplemental Oxygen
Status: RECRUITING
Conditions: Viral Lung Infection and Acute Respiratory Failure
Interventions: DRUG: Tozorakimab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Placebo-controlled Crossover Trial Using Cyproheptadine To Treat Children With Functional Abdominal Pain
Status: TERMINATED
Conditions: Functional Abdominal Pain
Interventions: DRUG: Cyproheptadine|DRUG: sugar pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of AMG 162 in Subjects With Advanced Cancer Currently Being Treated With Intravenous (IV) Bisphosphonates
Status: COMPLETED
Conditions: Bone Metastases in Men With Hormone-Refractory Prostate Cancer|Bone Metastases in Subjects With Advanced Breast Cancer|Bone Metastases in Subjects With Advanced Cancer or Multiple Myeloma
Interventions: GENETIC: AMG 162 180 mg (SC) q 12 weeks|DRUG: IV Bisphosphonate q 4 weeks|GENETIC: AMG 162- 180 mg q 4 weeks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Systemic Lidocaine Infusion for Pain Control in Ventral Hernia
Status: WITHDRAWN
Conditions: Post Operative Pain
Interventions: DRUG: Lidocaine Hydrochloride|DRUG: Lidocaine Hydrochloride|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: To Evaluate Sarilumab - SAR153191 (REGN88) - Auto-injector Device In Patients With Rheumatoid Arthritis
Status: COMPLETED
Conditions: RA
Interventions: DRUG: Sarilumab|DEVICE: Auto-Injector Device (AID)|DEVICE: Pre-filled Syringe (PFS)|DRUG: Methotrexate|DRUG: Sulfasalazine|DRUG: Leflunomide|DRUG: Hydroxychloroquine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Participants With Initially Unresectable Hepatocellular Carcinoma That is Treated With Atezolizumab and Bevacizumab Plus Transarterial Chemoembolization
Status: RECRUITING
Conditions: Unresectable Hepatocellular Carcinoma
Interventions: DRUG: Atezolizumab|DRUG: Bevacizumab|RADIATION: Transarterial Chemoembolization
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Acute Peripheral Vascular Effects, Safety and Tolerability in Subjects With Raynaud's Phenomenon Secondary to Systemic Sclerosis
Status: COMPLETED
Conditions: Raynaud's Phenomenon Secondary to Systemic Sclerosis
Interventions: DRUG: Alprostadil|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Multi-center, Placebo-controlled Study to Evaluate the Safety of GSK716155 and Its Effects on Myocardial Metabolism, Myocardial Function, and Exercise Capacity in Patients With NYHA Class II/III Congestive Heart Failure
Status: COMPLETED
Conditions: Heart Failure, Congestive
Interventions: DRUG: GSK716155|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Methohexital v Propofol as General Anesthetic in Patients on ACEIs or ARBs
Status: COMPLETED
Conditions: Hypotension|Anesthesia
Interventions: DRUG: Methohexital|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intravenous Ketamine Infusion on Postoperative Analgesia of Living Liver Donors
Status: UNKNOWN
Conditions: Liver Failure|Liver Transplant; Complications|Post Operative Pain
Interventions: DRUG: Low dose ketamine infusion|DRUG: 0.9% NaCl infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: TAF (Tenofovir Alafenamide) for Preventing Progression of Liver Disease in Non-cirrhotic Chronic HBV Infection With Normal ALT and Low Viral Load.
Status: RECRUITING
Conditions: Non-cirrhotic, Chronic Hepatitis B
Interventions: DRUG: Tenofovir alafenamide fumarate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Anesthesia Effects of Sevoflurane and Propofol Combined With Dexmedetomidine in Intraoperative Neuromonitoring During Thyroidectomy
Status: UNKNOWN
Conditions: Thyroid Nodule
Interventions: DRUG: Anesthesia was maintained with sevoflurane|DRUG: Anesthesia was maintained with propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Iron Absorption in Haiti
Status: COMPLETED
Conditions: Iron Deficiency
Interventions: OTHER: NaFeEDTA|OTHER: Ferrous fumarate|OTHER: NaFeEDTA + ferrous fumarate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Post-cesarean Analgesia With Epidural Morphine Following Epidural 2-chloroprocaine
Status: COMPLETED
Conditions: Physiological Effect of Drugs|Morphine|Analgesics|Analgesics, Opioid|Central Nervous System Depressants|Narcotics
Interventions: DRUG: 2% lidocaine with 1:200,000 epinephrine and epidural morphine|DRUG: 3% 2-chloroprocaine and epidural morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Selective Laser Trabeculoplasty After Failed Phacoemulsification With Eximer Laser Trabeculectomy
Status: COMPLETED
Conditions: Open Angle Glaucoma|Ocular Hypertension|Cataract
Interventions: PROCEDURE: Selective Laser Trabeculoplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hyperbaric Oxygen for Ulcerative Colitis
Status: TERMINATED
Conditions: Ulcerative Colitis
Interventions: PROCEDURE: Hyperbaric oxygen|PROCEDURE: Sham Hyperbaric Air
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Inspiratory Muscle Training for Patients Undergoing Esophageal Surgery
Status: WITHDRAWN
Conditions: Cancer of Esophagus|Cancer of the Esophagus|Esophageal Cancer|Esophagus Cancer|Esophagus Neoplasm|Neoplasms, Esophageal
Interventions: BEHAVIORAL: Inspiratory Muscle Training-Rehabilitation|OTHER: Questionnaires
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effects of Aromatherapy on Anxiety in Invasive Radiologic Procedure
Status: COMPLETED
Conditions: Anxiety|Anxiety Preoperative
Interventions: DRUG: Lavender Oil|DRUG: Bergamot Oil|OTHER: Water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Using Advanced Imaging Studies to Develop a Profile of High-grade Serous Ovarian Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Ovarian Cancer|High Grade Ovarian Serous
Interventions: DIAGNOSTIC_TEST: PET/MRI|DIAGNOSTIC_TEST: Contrast enhanced CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Motor Learning in Knee Osteoarthritis
Status: UNKNOWN
Conditions: Knee Osteoarthritis|Lower Extremity Biomechanics|Physiotherapy
Interventions: OTHER: External Focus Of Attention|OTHER: Internal Focus Of Attention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Multicenter, Open Label, To Evaluate The Efficacy And Satisfaction Of Patrex® In Men With Erectile Dysfunction.
Status: COMPLETED
Conditions: Erectile Dysfunction
Interventions: DRUG: sildenafil citrate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Methylnaltrexone as a Method to Improve Ticagrelor Uptake in Morphine Treated STEMI Patients
Status: COMPLETED
Conditions: STEMI|Morphine|Ticagrelor|Methylnaltrexone
Interventions: DRUG: Methylnaltrexone bromide (Relistor®).|DRUG: Sodium Chloride 9mg/mL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Local Anaesthetics Toxicity and Intralipid®
Status: COMPLETED
Conditions: Toxicity|Adverse Effects
Interventions: DRUG: placebo|DRUG: Intralipid®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of Neural Circuit Responses to Catechol-O-methyl Transferase (COMT) Inhibitors
Status: COMPLETED
Conditions: Impulsive Behavior
Interventions: DRUG: Tolcapone|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Full Mouth Ultrasonic Debridement Carried Out Either by Piezoelectric or Magnetostrictive Device
Status: UNKNOWN
Conditions: Periodontitis, Adult
Interventions: DEVICE: Full-mouth ultrasonic debridement with piezoelectric device (EMS, mini piezon)|DEVICE: Full-mouth ultrasonic debridement with magnetostrictive device (Cavitron Select, Dentsply)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Real World Treatment Experience of Patients With Breast, Lung, Ovarian, Multiple Myeloma, or Acute Myelogenous Leukemia Using Remote Symptom Monitoring
Status: RECRUITING
Conditions: Breast Cancer|Lung Cancer|Multiple Myeloma|Ovarian Cancer|Acute Myelogenous Leukemia
Interventions: OTHER: Web based survey
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phase IIa Study of the Product QGC001 Compared With Placebo in Patients With Essential Hypertension
Status: COMPLETED
Conditions: Essential Hypertension
Interventions: DRUG: QGC001|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Insulin Aspart Produced by Current Process and the NN2000 Process in Healthy Japanese
Status: COMPLETED
Conditions: Diabetes|Healthy
Interventions: DRUG: biphasic human insulin 30
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Performance of a Robot-assisted Minimally Invasive Direct Cochlear Access for Cochlear Implantation
Status: COMPLETED
Conditions: Sensorineural Hearing Loss
Interventions: DEVICE: HEARO|DEVICE: OTOPLAN
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Outcome Impact of Different Tranexamic Acid Regimen in Cardiac Surgery With Cardiopulmonary Bypass
Status: COMPLETED
Conditions: Homeostasis|Cardiac Surgery
Interventions: DRUG: Tranexamic Acid Dosage 1|DRUG: Tranexamic Acid Dosage 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Safety and Effectiveness Study of the MD-12-001 Stent in the Treatment of Superficial Femoral Artery or Popliteal Artery Blockages in Japanese Patients
Status: COMPLETED
Conditions: Arterial Occlusive Disease
Interventions: DEVICE: MD-12-001 Stent
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimizing Neurocognition With Whole Brain Radiation Therapy (WBRT) Using Upfront Pulsed Reduced Dose-Rate (PRDR) Technique
Status: RECRUITING
Conditions: Brain Metastases
Interventions: DRUG: Memantine -Twice Daily or Extended Release|RADIATION: WBRT utilizing the PRDR technique
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Siltuximab vs. Corticosteroids in Hospitalized Patients With COVID-19 Pneumonia
Status: COMPLETED
Conditions: COVID-19
Interventions: DRUG: Siltuximab|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hot EMR vs Underwater Cold EMR for Large Colonic Adenomas
Status: NOT_YET_RECRUITING
Conditions: Colonic Neoplasms|Colonic Adenoma|Colonic Lesion
Interventions: PROCEDURE: Traditional EMR|PROCEDURE: the cold snare ("CO"), underwater technique ("W"), and the use of submucosal lift ("L") in both study arms
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Omega-3 Fatty Acid for Critically Ill Patients.
Status: COMPLETED
Conditions: Sepsis
Interventions: DRUG: Omega 3|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Sorafenib With Capecitabine for Patients With Measurable Hepatocellular Carcinoma
Status: TERMINATED
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Sorafenib & Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Compliance, Tolerability, Efficacy and Adverse Events in Bipolar Tients From Valproic Acid to Depakote ER
Status: COMPLETED
Conditions: Mood Disorder
Interventions: DRUG: Valproic Acid and Depakote ER
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intravenous Immunoglobulin (IVIg) for the Treatment of Stiff-Man Syndrome (SMS)
Status: COMPLETED
Conditions: Muscle Rigidity|Spasm|Stiff Man Syndrome
Interventions: DRUG: IVIg
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Comparison Between Rifampicin and Gemifloxacin and Ciprofloxacin in Treatment of Rhinoscleroma
Status: UNKNOWN
Conditions: Rhinoscleroma
Interventions: DRUG: Gemifloxacin|DRUG: Ciprofloxacin|DRUG: Rifampicin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Post-extraction Collagen Sponge Application on Alveolar Osteitis
Status: NOT_YET_RECRUITING
Conditions: Alveolar Osteitis
Interventions: OTHER: Application of a collagen sponge after surgical extraction of impacted 3rd molar|OTHER: No collagen sponge application after surgical extraction of impacted 3rd molar
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Cardiopulmonary Rehabilitation in Post-acute COVID-19 Syndrome
Status: NOT_YET_RECRUITING
Conditions: Post Acute COVID-19 Syndrome
Interventions: OTHER: Cardiopulmonary rehabilitation|OTHER: Health education
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of mCIMT on Upper Extremity Functions of Stroke Patients With Right/Left Hemiplegia
Status: UNKNOWN
Conditions: Stroke Patients
Interventions: OTHER: Modified Constraint Induced Movement Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Investigation of Peginterferon Alfa-2a on Optimal in Chronic Hepatitis B Patients Who Have a High Risk of HCC
Status: UNKNOWN
Conditions: Hepatitis B
Interventions: DRUG: Peginterferon Alfa-2A|DRUG: Adefovir, entecavir,tenofovir, either of them
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of LY3526318 in Healthy Male Japanese Participants
Status: WITHDRAWN
Conditions: Healthy
Interventions: DRUG: LY3526318|DRUG: Placebo|DRUG: Iohexol|DRUG: Simvastatin|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of orBec® as Monotherapy in the Treatment of Patients With Upper GI Symptoms Caused by Chronic Graft Versus Host Disease (GVHD)
Status: TERMINATED
Conditions: Chronic Gastrointestinal Graft vs Host Disease
Interventions: DRUG: orBec|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Preoperative Point of Care Ultrasound Guided Fluid Optimization and Intravenous Ondansetron to Prevent General Anesthesia-Induced Hypotension
Status: NOT_YET_RECRUITING
Conditions: Intra-operative Hypotension
Interventions: DRUG: fluid boluses guided by IVC diameter via US/administration of pre-operative IV Odansetrone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Gut Peptides and Bone Remodeling in Individuals With Spinal Cord Injury
Status: RECRUITING
Conditions: Spinal Cord Injuries
Interventions: OTHER: Meal test|OTHER: GIP|OTHER: GLP-2|OTHER: GIP + GLP-2|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study Evaluating the Safety and Pharmacokinetics of Escalating Doses of Forimtamig in Participants With Relapsed or Refractory Multiple Myeloma (r/r MM)
Status: RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: Forimtamig
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Increasing Fluids in Older Adults to Prevent & Treat Pressure Ulcers
Status: COMPLETED
Conditions: Pressure Ulcers
Interventions: DIETARY_SUPPLEMENT: Fluid intervention|DIETARY_SUPPLEMENT: Fluid intervention plus 10 ml/kg/day
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Heart and Heart-Lung Transplant Patient Outcomes Following Pulmonary Rehabilitation
Status: UNKNOWN
Conditions: Emphysema|Alveolitis, Fibrosing|Cystic Fibrosis|Bronchiectasis|Lung Diseases
Interventions: PROCEDURE: Pulmonary rehabilitation programme
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Enhanced Recovery After Surgery in Colorectal Surgery: A Large-Scale Quality Improvement Project
Status: COMPLETED
Conditions: Colorectal Surgery|Quality Improvement|Perioperative Care|ERAS
Interventions: PROCEDURE: ERAS perioperative care|PROCEDURE: Standard perioperative care|PROCEDURE: Noninvasive hemodynamic monitoring
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: BLI1100-202: BLI1100 for the Treatment of Moderate to Severe Acne Vulgaris
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: BLI1100|DRUG: BLI1100 - modified formulation|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Impact of a New Complement to Physiotherapy Intervention for Positional Torticollis in Infants
Status: TERMINATED
Conditions: Torticollis
Interventions: OTHER: Booklet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bowel Preparation by Face-to-face Re-education on the Day of Colonoscopy for Outpatient: a RCT
Status: COMPLETED
Conditions: Bowel Preparation
Interventions: BEHAVIORAL: telephone re-education(TRE)|BEHAVIORAL: face-to-face re-education (FFRE)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Oral Evaluation by the Nurses From the Office of Access to Healthcare ("PASS") for Vulnerable People - PASSDENT Study
Status: COMPLETED
Conditions: Homeless and Low Incomes People, Refugees
Interventions: OTHER: Oral and dental evaluation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Giant Left Atrium Atrial fibrillatioN CathEter Ablation, Posterior Box Isolation vs. Dallas Lesion Set
Status: NOT_YET_RECRUITING
Conditions: Atrial Fibrillation
Interventions: PROCEDURE: Circumferential pulmonary vein isolation(CPVI) group|PROCEDURE: Posterior box isolation(POBI) group|PROCEDURE: POBI+Anterior linear ablation(AL) group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vitamin D and Mortality in Heart Failure
Status: COMPLETED
Conditions: Congestive Heart Failure
Interventions: DRUG: Vitamin D|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Is the WHO Recommended Dose of Pralidoxime Effective in the Treatment of Organophosphorus Poisoning?
Status: COMPLETED
Conditions: Deaths
Interventions: DRUG: Pralidoxime
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sucking Pattern of Preterm Infants Using Cup or Bottle Before Breastfeeding
Status: TERMINATED
Conditions: Infant, Very Low Birth Weight
Interventions: PROCEDURE: cup feeding|PROCEDURE: bottle feeding
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Gratitude Intervention in Promoting Self-care in Patients With Myocardial Infarction
Status: ENROLLING_BY_INVITATION
Conditions: Myocardial Infarction, Acute
Interventions: BEHAVIORAL: Gratitude list|BEHAVIORAL: List of any event
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Study in Healthy Volunteers and in Participants With Chronic Hepatitis B to Assess Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single and Multiple Doses of RO7020531
Status: COMPLETED
Conditions: Hepatitis B, Chronic
Interventions: OTHER: Placebo|DRUG: RO7020531
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Electroacupuncture as a Complement to Usual Care for Patients With Non-acute Pain After Back Surgery
Status: COMPLETED
Conditions: Low Back Pain|Pain, Postoperative|Failed Back Surgery Syndrome
Interventions: DEVICE: electroacupuncture and usual care|DEVICE: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Real-time Continuous Glucose Monitoring System in Overweight or Obese Adults With Prediabetes
Status: UNKNOWN
Conditions: Continuous Glucose Monitoring|Prediabetic State|Obesity
Interventions: DEVICE: RT-CGM|OTHER: SMBG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to Assess the Efficacy and Safety of Twice-Daily Dose Regimens of an Oral Calcimimetic Agent AMG 073 (Cinacalcet) in Primary Hyperparathyroidism (PHPT)
Status: COMPLETED
Conditions: Hyperparathyroidism, Primary
Interventions: DRUG: placebo|DRUG: cinacalcet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Designed to Determine if the Drugs Albuterol (Salbutamol) and Fluticasone Have an Effect on the Pharmacokinetics of the Investigational Product Technosphere® Insulin Inhalation Powder in Healthy Volunteers
Status: COMPLETED
Conditions: Diabetes Mellitus|Healthy Subjects
Interventions: DRUG: Technosphere Insulin (TI) Inhalation Powder|DRUG: Albuterol (Salbutamol)|DRUG: Fluticasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Use of Tocilizumab in the Management of Patients Who Have Severe COVID-19 With Suspected Pulmonary Hyperinflammation
Status: UNKNOWN
Conditions: Covid19 Pneumonia
Interventions: DRUG: Tocilizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Registry of Corona Virus Disease 2019 (Covid-19) Patients With Neuromuscular Involvement
Status: UNKNOWN
Conditions: COVID|Sars-CoV2|Corona Virus Infection|Myositis|Myocarditis
Interventions: DIAGNOSTIC_TEST: laboratory biomarkers|DIAGNOSTIC_TEST: muscle ultrasound
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of the Pathophysiology of RNU4ATAC and RTTN Associated Syndromes
Status: NOT_YET_RECRUITING
Conditions: Taybi Linder Syndrome|Microcephalic Osteodysplastic Primordial Dwarfism Types I and III|Roifman Syndrome|Lowry Wood Syndrome
Interventions: OTHER: Blood samples|OTHER: Skin biopsies|OTHER: Fetal samples
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Multisectoral Strategy to Address Persistent Drivers of the HIV Epidemic in East Africa
Status: ACTIVE_NOT_RECRUITING
Conditions: HIV|Hypertension|Alcohol Drinking|Maternal Child Health|Cost Effectiveness
Interventions: OTHER: Mobility Dynamic Treatment Intervention|OTHER: Health Living Intervention for Heavy Alcohol Users|OTHER: Hypertension Linkage|OTHER: PrEP/PEP at Outpatient Clinics|OTHER: PrEP/PEP at Antenatal Clinics|OTHER: PrEP/PEP at Community Households|OTHER: Standard of Care|OTHER: Hypertension Community
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Functionalized Bioink Delivering Biomolecules for the Treatment of Craniofacial Diseases
Status: NOT_YET_RECRUITING
Conditions: Craniofacial Defects, Subtle|Skull Defect|Craniosynostoses
Interventions: OTHER: multiomic profiling
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Influence of a Multi-parametric Optimization Strategy for General Anesthesia on Postoperative Morbidity and Mortality
Status: COMPLETED
Conditions: Coronary; Ischemic|Arrhythmias, Cardiac|Heart Failure|Peripheral Vascular Diseases|Dementia|Stroke|Pulmonary Disease, Chronic Obstructive|Respiratory Insufficiency|Alcoholism|Cancer|Diabetes|Renal Insufficiency
Interventions: PROCEDURE: OPTI-AGED|PROCEDURE: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of Intratumoral Injection of Interleukin-2 and Ipilimumab in Patients With Unresectable Stages III-IV Melanoma
Status: COMPLETED
Conditions: Melanoma
Interventions: DRUG: Intratumoral Ipilimumab and Interleukin-2
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Topical Capsaicin Cream for Stable Angina
Status: TERMINATED
Conditions: Stable Angina
Interventions: DRUG: Capsaicin|OTHER: Placebo cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Everolimus, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma
Status: COMPLETED
Conditions: Brain and Central Nervous System Tumors
Interventions: DRUG: everolimus|DRUG: temozolomide|RADIATION: radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Dietary Flaxseed on Symptoms of Cardiovascular Disease in Patients With Peripheral Arterial Disease
Status: COMPLETED
Conditions: Peripheral Arterial Disease
Interventions: DIETARY_SUPPLEMENT: Flaxseed|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Clipped Versus Handsewn Arteriovenous Fistula Anastomosis
Status: TERMINATED
Conditions: Arteriovenous Fistula Complications and Failure
Interventions: DEVICE: Clipped anastomosis|PROCEDURE: Handsewn anastomosis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effects of Testosterone Plus Dutasteride or Placebo on Muscle Strength, Body Composition and Metabolism in Transmen
Status: COMPLETED
Conditions: Transgenderism|Hypogonadism
Interventions: DRUG: dutasteride 5 mg/day|DRUG: Testosterone Undecanoate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Endoscopic Tri-Modal Imaging to Distinguish Functional Dyspepsia From Reflux Disease
Status: COMPLETED
Conditions: Gastroesophageal Reflux Disease|Dyspepsia|Bile Reflux
Interventions: DEVICE: Endoscopic Tri-Modal Imaging|DRUG: Omeprazole|OTHER: Analysis of gastric juice
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Prospective Evaluation of the Efficacy and Safety of Submucosal Endoscopy
Status: ACTIVE_NOT_RECRUITING
Conditions: Gastrointestinal Neoplasia|Hirschsprung's Disease|Esophageal Obstruction|Gastroparesis|Spastic Esophageal Disorders|Zenker's Diverticulum
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of F0002-ADC in Chinese Patients With Refractory or Recurrent CD30+ Hematologic Malignancies.
Status: COMPLETED
Conditions: Refractory or Recurrent CD30+ Hematologic Malignancies
Interventions: DRUG: F0002-ADC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Safety, Pharmacokinetics, and Efficacy of Combination Treatment of AL-335, Odalasvir, and Simeprevir in Japanese Participants With Chronic Hepatitis C Genotype 1 or 2 Virus Infection, With or Without Compensated Cirrhosis Who Are Direct Acting Antiviral Treatment-naive
Status: COMPLETED
Conditions: Hepatitis C, Chronic
Interventions: DRUG: AL-335|DRUG: Odalasvir (ODV)|DRUG: Simeprevir (SMV)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Two Doses of ATIR101, a T-lymphocyte Enriched Leukocyte Preparation Depleted of Host Alloreactive T-cells, in Patients With a Hematologic Malignancy Who Received a Hematopoietic Stem Cell Transplantation From a Haploidentical Donor
Status: COMPLETED
Conditions: Acute Myeloid Leukemia|Acute Lymphoblastic Leukemia|Myelodysplastic Syndrome
Interventions: BIOLOGICAL: ATIR101|PROCEDURE: Haploidentical hematopoietic stem cell transplantation (HSCT)|PROCEDURE: TBI regime|PROCEDURE: Non-TBI regime
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of DPX-Survivac Therapy in Patients With Recurrent Ovarian Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Recurrent Epithelial Ovarian Cancer|Recurrent Fallopian Tube Cancer|Recurrent Peritoneal Cancer
Interventions: OTHER: DPX-Survivac|DRUG: Cyclophosphamide|DRUG: Epacadostat (INCB024360)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I, Open Interaction Study Between GLPG1837 and Midazolam in Healthy Male Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: GLPG1837 500 mg|DRUG: Midazolam|DRUG: GLPG1837 1000 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Laparoscopic Sleeve Gastrectomy Plus Weight Watchers vs. Weight Watchers Alone in Underserved Minority Women
Status: WITHDRAWN
Conditions: Morbid Obesity
Interventions: PROCEDURE: Laparscopic Sleeve Gastrectomy|BEHAVIORAL: Weight Watchers Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Medical vs Surgical Treatment in OSA Among Children
Status: UNKNOWN
Conditions: To Evaluate PSQ as Clinical Tool in the Decision Between Medical and Surgical Treatment for Adenotonsillar Hypertrophy|To Determine Clinical Response to Montelukast or Nasal Steroids Based on PSQ Results
Interventions: DRUG: Montelukast|DRUG: Fluticasone Furoate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Somatostatin Receptor Imaging in NPC, EBV Related Cancers
Status: RECRUITING
Conditions: Nasopharyngeal Cancer|Epstein-Barr Virus Related Carcinoma
Interventions: RADIATION: FDG-PET|RADIATION: Galium-68 DOTATATE
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Analysis of Bone Micro-Architecture as a Clinical Biomarker for Image-Based Fracture Risk Estimation.
Status: UNKNOWN
Conditions: Osteoporosis
Interventions: RADIATION: Dual Energy CT (DECT)|RADIATION: DEXA
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Bevacizumab With or Without Radiation Therapy in Treating Patients With Recurrent Glioblastoma
Status: COMPLETED
Conditions: Adult Giant Cell Glioblastoma|Adult Glioblastoma|Adult Gliosarcoma|Recurrent Adult Brain Tumor
Interventions: BIOLOGICAL: bevacizumab|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neurobiological Correlates of Post Traumatic Stress Disorder (PTSD) During Rapid Eye Movement (REM) Sleep
Status: COMPLETED
Conditions: Post-Traumatic Stress Disorder
Interventions: OTHER: Sleep data recording|OTHER: PET scan - waking|OTHER: PET scan - REM Sleep
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Mental Health Services Engagement Program for Racial and Ethnic Minority Young Adults
Status: NOT_YET_RECRUITING
Conditions: Psychosis|Bipolar and Related Disorders|Depressive Disorder
Interventions: BEHAVIORAL: Just Do You|BEHAVIORAL: Component A|BEHAVIORAL: Component B|BEHAVIORAL: Component C
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Safety and Efficacy Study of GDC-0853 Compared With Placebo and Adalimumab in Participants With Rheumatoid Arthritis (RA)
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: GDC-0853|DRUG: Adalimumab|DRUG: Folic Acid|DRUG: MTX|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Rituximab Treatment in Sjogren's Syndrome
Status: COMPLETED
Conditions: Sjogren's Syndrome
Interventions: DRUG: rituximab (anti-CD20)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT