pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Studying Biomarkers in Samples From Young Patients With Rhabdoid Tumors
Status: COMPLETED
Conditions: Kidney Cancer
Interventions: GENETIC: DNA analysis|GENETIC: fluorescence in situ hybridization|GENETIC: gene expression analysis|GENETIC: gene mapping|GENETIC: microarray analysis|GENETIC: polymerase chain reaction|GENETIC: protein expression analysis|OTHER: laboratory biomarker analysis|OTHER: medical chart review
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Mobility and Therapeutic Benefits Resulting From Exoskeleton Use in a Home and Community Setting (SC140121 Study 3)
Status: WITHDRAWN
Conditions: Spinal Cord Injury
Interventions: DEVICE: Indego Exoskeleton
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Trial Of Normal Saline Versus Ringer's Lactate In Paediatric Trauma Patients
Status: COMPLETED
Conditions: Trauma
Interventions: DRUG: Normal Saline|DRUG: Ringer's Lactate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Improving Mobility and Reducing Fatigue in People With Multiple Sclerosis by Electrical Stimulation Therapy
Status: WITHDRAWN
Conditions: Multiple Sclerosis
Interventions: DEVICE: Transcutaneous electrical nerve stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial to Evaluate AZD7648 Alone and in Combination With Other Anti-cancer Agents in Patients With Advanced Cancers.
Status: COMPLETED
Conditions: Advanced Malignancies
Interventions: DRUG: AZD7648|DRUG: PLD
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Investigation of the Visual Outcomes and Safety of a Trifocal Toric IOL in an Asian Population
Status: COMPLETED
Conditions: Aphakia|Corneal Astigmatism
Interventions: DEVICE: ACRYSOF® IQ PanOptix® Toric Trifocal IOL|PROCEDURE: Cataract surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Study of the McGrath MAC Video Laryngoscope With the King Vision
Status: COMPLETED
Conditions: Video Laryngoscopic Device Usage in Novice Users
Interventions: PROCEDURE: King Vision video laryngoscope|PROCEDURE: McGrath MAC video laryngoscope
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study on Intensive Multi-acupuncture in the Treatment of Lumbar Muscle Strain.
Status: NOT_YET_RECRUITING
Conditions: Lumbar Muscle Strain
Interventions: PROCEDURE: acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial to Determine the Comparability of Ipratropium Bromide Hydrofluoroalkane (HFA)-134a Inhalation Aerosol to ATROVENT® Chlorofluorocarbon (CFC) Inhalation Aerosol, in Patients With Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Ipratropium bromide HFA-134a inhalation aerosol|DRUG: Atrovent CFC inhalation aerosol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ADG126, ADG126 in Combination With Anti PD1 Antibody, and ADG126 in Combination With ADG106 in Advanced/Metastatic Solid Tumors
Status: COMPLETED
Conditions: Advanced/Metastatic Solid Tumors
Interventions: BIOLOGICAL: ADG126 Mono|BIOLOGICAL: ADG126-anti PD1|BIOLOGICAL: ADG126-ADG106
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Care Program for the Management of Post-ICU Syndrome and Chronic Pain After COVID-19 Infection.
Status: COMPLETED
Conditions: Post ICU Syndrome|Chronic Pain|Covid-19
Interventions: BEHAVIORAL: Intervention program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy Study of a New Chemotherapy Agent to Treat Non-small-cell Lung Cancer
Status: COMPLETED
Conditions: Carcinoma, Non Small Cell Lung
Interventions: DRUG: Sagopilone (BAY86-5302, ZK 219477)|DRUG: Sagopilone (BAY86-5302, ZK 219477)|DRUG: Sagopilone (BAY86-5302, ZK 219477)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vestibular Infants Screening-Flanders
Status: COMPLETED
Conditions: Vestibular Disorder|Hearing Impaired Children
Interventions: DIAGNOSTIC_TEST: cervical vestibular evoked myogenic potentials (cVEMP)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Unmodified Versus Leuko-Reduced Allogeneic Red Blood Cells Transfusion in Cancer Patients
Status: COMPLETED
Conditions: Cancer|Surgery
Interventions: PROCEDURE: transfusion of allogeneic red blood cell concentrate|PROCEDURE: transfusion of leuko-reduced red blood cell concentrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of DU-176b Aged 80 Years or Older
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DRUG: Du-176b|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Modification of Goal-directed and Habitual Behavior in Addiction
Status: COMPLETED
Conditions: Tobacco Use Disorder
Interventions: BEHAVIORAL: standard smoking cessation program (SCP)|BEHAVIORAL: Cognitive remediation treatment (CRT)|BEHAVIORAL: Implicit computer-based habit-modifying training (ICHT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fully Guided Versus Conventionally Guided Implant Placement by Dental Students
Status: UNKNOWN
Conditions: Jaw, Edentulous, Partially
Interventions: PROCEDURE: Fully-guided vs. conventionally guided implant placement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Autologous Umbilical Cord Blood Treatment of Neonate With CHD
Status: UNKNOWN
Conditions: Congenital Heart Disease|Brain Injuries|Low Cardiac Output Syndrome|Neonatal Disorder
Interventions: BIOLOGICAL: Autlogous UCB infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Studying Genes in Samples From Younger Patients With Acute Megakaryoblastic Leukemia
Status: COMPLETED
Conditions: Childhood Acute Megakaryocytic Leukemia (M7)|Childhood Acute Myeloid Leukemia/Other Myeloid Malignancies
Interventions: OTHER: laboratory biomarker analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Strengthening Palliative Care in Primary Health Care Through Knowledge Enhancement
Status: COMPLETED
Conditions: Palliative Care|Nurse|Community Health Services
Interventions: OTHER: educational intervention (SPARK)|OTHER: electronic version of the modules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Efficacy of Clindamycin Phosphate 1% Gel Versus Once-daily Dapsone 5% Gel in the Treatment of Moderate Acne Vulgaris
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: Clindamycin and Dapsone gel for 03 months
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ranolazine a Potential New Therapeutic Application
Status: WITHDRAWN
Conditions: Myocardial Stunning
Interventions: DRUG: Ranolazine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Marijuana and Prescription Medications in Mood, Performance and Sleep
Status: COMPLETED
Conditions: Marijuana Dependence
Interventions: DRUG: eszopiclone|DRUG: Placebo|DRUG: ramelteon|DRUG: zolpidem
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Physiological and Sensory Responses to Prolonged Fasting in Humans
Status: ACTIVE_NOT_RECRUITING
Conditions: Fasting|Metabolic Disturbance|Energy Supply; Deficiency|Adiposity
Interventions: OTHER: Prolonged Fasting
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of CC-90006 in Healthy Subjects
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Placebo|DRUG: CC-90006
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cocaine Withdrawal and Pharmacotherapy Response
Status: COMPLETED
Conditions: Cocaine Dependence|Opiate Dependence
Interventions: DRUG: sugar pill|DRUG: Carvedilol 25 mg|DRUG: Carvedilol 50 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Composite Restorations Performed by Placing Polyethylene Fiber
Status: ACTIVE_NOT_RECRUITING
Conditions: Endodontically Treated Teeth
Interventions: OTHER: Polyethylene Fiber
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Transcranial Magnetic Stimulation to Reduce Craving for Individuals With Opioid Use Disorder Taking Buprenorphine
Status: WITHDRAWN
Conditions: Opioid-use Disorder
Interventions: DEVICE: Transcranial Magnetic Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Platinum-Based Chemotherapy and Durvalumab for the Treatment of Stage IIIB or IV Non-small Cell Lung Cancer
Status: WITHDRAWN
Conditions: Lung Non-Small Cell Carcinoma|Stage IIIB Lung Cancer AJCC v8|Stage IV Lung Cancer AJCC v8|Stage IVA Lung Cancer AJCC v8|Stage IVB Lung Cancer AJCC v8
Interventions: DRUG: Carboplatin|BIOLOGICAL: Durvalumab|DRUG: Paclitaxel|DRUG: Pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Hemodynamic Response in Cardiopulmonary Bypass Graft After Cardiopulmonary Bypass Using Transesophegeal Echocardiography
Status: COMPLETED
Conditions: Cardiopulmonary Bypass Graft
Interventions: DRUG: epinephrine and levosimendan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Carbon Dioxide Acupulse Laser Treatment Versus Sham Treatment and Sexual Dysfunction.
Status: UNKNOWN
Conditions: Sexual Dysfunction
Interventions: DEVICE: Carbon dioxide laser|DEVICE: Sham laser treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Effects of Treadmill Versus Cycling Endurance Training in Patients With COPD
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: OTHER: treadmill endurance training|OTHER: cycling endurance training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A 24-weeks, Multi-center, Randomized, Double-blind, Placebo Controlled Study to Evaluate the Efficacy and Safety of Donepezil Hydrochloride in Chinese Subjects With Severe Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer's Type Dementia
Interventions: DRUG: E2020|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Eribulin Mesylate and Everolimus in Treating Patients With Triple-Negative Metastatic Breast Cancer
Status: COMPLETED
Conditions: Estrogen Receptor Negative|HER2/Neu Negative|Progesterone Receptor-negative|Stage IV Breast Cancer|Triple-negative Breast Carcinoma
Interventions: DRUG: everolimus|DRUG: eribulin mesylate|OTHER: pharmacological study|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Learning Curve of Endobronchial Intubation Using Video Laryngoscopes
Status: UNKNOWN
Conditions: Endobronchial Intubation
Interventions: OTHER: The simulated "easy" airway|OTHER: The simulated "difficult" airway|DEVICE: King Vision Laryngoscope|DEVICE: MacGrath Laryngoscope
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Autologous Adipose Tissue Derived Mesenchymal Stem Cells Therapy for Patients With Knee Osteoarthritis
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: BIOLOGICAL: Mesenchymal stem cells low-dose group|BIOLOGICAL: Mesenchymal stem cells mid-dose group|BIOLOGICAL: Mesenchymal stem cells high-dose group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Cuminum Cyminum Herbal =Preparation in Inhibition of Plaque and Gingivitis.
Status: COMPLETED
Conditions: Chronic Gingivitis
Interventions: DRUG: Cuminum Cyminum|DRUG: herbal Mouthwash
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Primary Care Intervention Strategy for Anxiety Disorders
Status: COMPLETED
Conditions: Post-traumatic Stress Disorder|Generalized Anxiety Disorder|Panic Disorder|Social Anxiety Disorder
Interventions: BEHAVIORAL: Cognitive-behavioral therapy|DRUG: Psychotropic medication optimization|BEHAVIORAL: Treatment as Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: HR+/HER2- Advanced or Metastatic Breast Cancer Patients Treated With Sacituzumab Govitecan
Status: RECRUITING
Conditions: Breast Cancer Stage IV
Interventions: DRUG: Sacituzumab Govitecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Nefopam/Fentanyl Postoperative Intravenous Patient-Controlled-Analgesia
Status: COMPLETED
Conditions: Laparotomy
Interventions: DRUG: Nefopam|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Computer-Supported Management of Medical-Legal Issues Impacting Child Health
Status: COMPLETED
Conditions: Legal Rights|Medicolegal Aspects
Interventions: OTHER: CHICA MLP Module|OTHER: CHICA without the MLP module
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Low-level Laser Therapy in the Prevention of Chemotherapy-induced Mucositis in Children and Young Adults
Status: RECRUITING
Conditions: Mucositis Oral
Interventions: DEVICE: Low-Level Laser Therapy|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Safety, Efficacy and Tolerability of Nexvax-2 in Patients With Celiac Disease (CeD)
Status: UNKNOWN
Conditions: Celiac Disease|Celiac|Intestinal Disease|Malabsorption Syndromes|Gastrointestinal Disease|Digestive System Disease|Gluten Sensitivity|Autoimmune Diseases
Interventions: BIOLOGICAL: Nexvax2|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment Of The Inhalation Profiles Of Four Dry Powder Inhalers In Patients With Variable Degrees Of Lung Obstruction
Status: COMPLETED
Conditions: Asthma|Pulmonary Disease, Chronic Obstructive
Interventions: DEVICE: CRC-749|DEVICE: Diskus|DEVICE: Twisthaler|DEVICE: Miat Monohaler
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Evaluate the Safety and Immunogenicity of GlaxoSmithKline (GSK) Biologicals' Experimental Rabies Vaccine in Healthy Adults
Status: COMPLETED
Conditions: Virus Diseases
Interventions: BIOLOGICAL: Low dose formulation of RG SAM (CNE) vaccine (GSK3903133A)|BIOLOGICAL: Medium dose formulation of RG SAM (CNE) vaccine (GSK3903133A)|BIOLOGICAL: Lower dose formulation of RG SAM (CNE) vaccine (GSK3903133A)|BIOLOGICAL: Lowest dose formulation of RG SAM (CNE) vaccine (GSK3903133A)|DRUG: Saline Placebo|BIOLOGICAL: RabAvert
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Adult Oral Ibuprofen Study for ED Pain Patients
Status: COMPLETED
Conditions: Pain, Acute
Interventions: DRUG: Oral Ibuprofen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Interprofessional Management of Chronic Back Pain in Rural and Remote Setting: Use of Telehealth vs. Secure Laptop-based Videoconferencing
Status: COMPLETED
Conditions: Back Pain Lower Back Chronic
Interventions: OTHER: interprofessional back pain assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Bathing Persons With Alzheimer's Disease aT Home (The BATH Study)
Status: COMPLETED
Conditions: Alzheimer Disease
Interventions: BEHAVIORAL: Bathing Support Intervention (BSI)|BEHAVIORAL: Caregiver reminiscence with coaching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: A Global Study Comparing Risankizumab to Placebo in Adult Participants With Moderate to Severe Hidradenitis Suppurativa
Status: COMPLETED
Conditions: Hidradenitis Suppurativa
Interventions: DRUG: Risankizumab|DRUG: Placebo for risankizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Donor Stem Cell Transplant With Treosulfan, Fludarabine, and Thiotepa in Treating Patients With Non-malignant Disorders
Status: RECRUITING
Conditions: Non-Neoplastic Hematologic and Lymphocytic Disorder
Interventions: DRUG: Thiotepa|DRUG: Treosulfan|DRUG: Fludarabine Phosphate|BIOLOGICAL: Rabbit Anti-Thymocyte Globulin|PROCEDURE: Allogeneic Hematopoietic Stem Cell Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The MEADOW PROJECT (Mending the Effects of Alcohol and Depression on Women) and The Bridge Program (Connecting Recovery Treatment and Behavioral Health)
Status: COMPLETED
Conditions: Alcohol Dependence|Depression
Interventions: BEHAVIORAL: Interpersonal Psychotherapy for Co-occurring Alcohol Dependence and Major Depression (IPT-ADMD)|BEHAVIORAL: Treatment as Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fixed Dose Study of PD 0332334 and Paroxetine for the Treatment of Generalized Anxiety Disorder
Status: TERMINATED
Conditions: Anxiety Disorders
Interventions: DRUG: No drug name provided by Sponsor; drug referenced as PD 0332334|DRUG: Paroxetine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: AZD4205 in Peripheral T Cell Lymphoma Following First-Line Therapy (JACKPOT26)
Status: ACTIVE_NOT_RECRUITING
Conditions: Peripheral T-cell Lymphoma
Interventions: DRUG: AZD4205
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Participants With Chronic Kidney Disease Previously Treated With REACT
Status: RECRUITING
Conditions: Diabetic Kidney Disease|CAKUT|Chronic Kidney Diseases
Interventions: BIOLOGICAL: Renal Autologous Cell Therapy (REACT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Seroimmunity 2007 and Sub Study of the Swedish Population Regarding Vaccine Preventable Disease
Status: UNKNOWN
Conditions: Diphtheria|Tetanus|Pertussis|Polio|Haemophilus Influenzae Type B|Measles|Mumps|Rubella|Hepatitis B
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Anti-PD-1 Antibody Combined With Peg-Asparaginase and Chidamide for the Early Stage of NK/T Cell Lymphoma
Status: RECRUITING
Conditions: Immune Checkpoint Inhibitor|Chemotherapy Effect|Epigenetic Disorder|NK/T-cell Lymphoma of Nasal Cavity
Interventions: DRUG: Anti-PD-1 antibody+Peg-Asparaginase+Chidamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Leeds Women's Wellbeing (LWW) Study
Status: COMPLETED
Conditions: Weight Loss
Interventions: OTHER: Healthy eating diet (Diet A) or healthy eating diet combined with advice to increase fibre intake (Diet B) to at least 25g/day
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparative Effectiveness of a Peer-led O2 Infoline for Patients and Caregivers
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: BEHAVIORAL: Written education material (basic)|BEHAVIORAL: Additional education material|BEHAVIORAL: PELICAN-Proactive|BEHAVIORAL: PELICAN-Reactive
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Interventions to Improve Non-communicable Disease Management During the Pandemic
Status: RECRUITING
Conditions: Noncommunicable Diseases|COVID-19
Interventions: OTHER: Digital health interventions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: POCT PCT in Outpatient LRTI
Status: COMPLETED
Conditions: Antimicrobial Stewardship|Exacerbation of Allergic Asthma|Exacerbation Copd|Community-acquired Pneumonia|Lower Respiratory Tract and Lung Infections
Interventions: DIAGNOSTIC_TEST: Point-of-care Test
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Impact of Dural Puncture Epidural Versus Traditional Lumbar Epidural on Onset of Labor Analgesia
Status: COMPLETED
Conditions: Labor Pain|Labor Analgesia
Interventions: PROCEDURE: Lumbar Epidural|PROCEDURE: Dural Puncture Epidural
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: iTreatOCD: Predicting the Efficacy of Internet-based Cognitive Behavioral Therapy in Obsessive-compulsive Disorder
Status: RECRUITING
Conditions: Obsessive-Compulsive Disorder
Interventions: BEHAVIORAL: ICBT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Targeting Dopamine Therapy in RLS
Status: UNKNOWN
Conditions: Restless Legs Syndrome
Interventions: BEHAVIORAL: Motor Task|DRUG: Levodopa tablet|BEHAVIORAL: Sham non-motor task|DRUG: Placebo pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study of Indomethacin Capsules to Treat Pain Following Surgery in Children Ages 6 to <17 Years of Age
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: DRUG: Indomethacin Capsules low dose|DRUG: Indomethacin Capsules high dose
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antineoplaston Therapy in Treating Children With Rhabdoid Tumor of the Central Nervous System
Status: TERMINATED
Conditions: Rhabdoid Neoplasm of CNS
Interventions: DRUG: Antineoplaston therapy (Atengenal + Astugenal)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Determination of the Optimal Spontaneous Breathing Trial During Weaning of Mechanical Ventilation
Status: TERMINATED
Conditions: Intensive Care Unit|Invasive Mechanical Ventilation|Ready to Wean From Ventilation
Interventions: PROCEDURE: T-piece|PROCEDURE: PSV 7 and PEEP 0|PROCEDURE: PSV 0 and PEEP 0
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Indomethacin for Refractory Chronic Cough
Status: UNKNOWN
Conditions: Refractory Chronic Cough
Interventions: DRUG: indomethacin|DRUG: Placebo|DRUG: Omeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Dexmedetomidine on the Heart Beat During Elective Surgery in Children
Status: COMPLETED
Conditions: Myocardial Repolarization|Healthy
Interventions: DRUG: Dexmedetomidine|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Prazosin on the Attention-Enhancing Effects of Nicotine
Status: WITHDRAWN
Conditions: no Condition, Basic Science
Interventions: DRUG: Placebo|DRUG: Nicotine|DRUG: Prazosin|DRUG: Nicotine + Prazosin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparing the Effectiveness of Individual vs. Household Treatment for Scabies in Lambaréné, Gabon
Status: COMPLETED
Conditions: Scabies|Households
Interventions: DRUG: Benzyl Benzoate 25% Topical Application Lotion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of the APTIMA® COMBO 2® Assay Using the PANTHER™ System
Status: COMPLETED
Conditions: Chlamydia Trachomatis|Neisseria Gonorrhoeae Infection
Interventions: DEVICE: APTIMA COMBO 2 Assay (AC2 Assay)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Formulations of Liposomal Local Anesthetics
Status: COMPLETED
Conditions: Underdosing of Local Anesthetics, Initial Encounter
Interventions: DRUG: Ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study of F520 in Relapsed/Refractory Primary Central Nervous System Lymphoma (PCNSL) or Secondary Central Nervous System Lymphoma (SCNSL)
Status: UNKNOWN
Conditions: Primary Central Nervous System Lymphoma|Secondary Central Nervous System Lymphoma
Interventions: DRUG: F520
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Kinesiotaping on Respiratory Muscles in Very Preterm Infants
Status: COMPLETED
Conditions: Preterm|Premature|Infant, Newborn, Diseases|Respiratory Distress Syndrome|Neonatal Respiratory Distress
Interventions: OTHER: kinesiotaping application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Effect of A-PRF and L-PRF on Outcomes After Removal of Impacted Mandibular Third Molar
Status: COMPLETED
Conditions: Pain, Postoperative|Trismus|Swelling
Interventions: GENETIC: Advanced Platelet Rich Fibrin (A-PRF)|GENETIC: Leukocyte- and platelet-rich fibrin (L-PRF)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Prebiotic Supplementation and Exercise on Inflammatory Markers, Vascular Function and Cognition in CKD
Status: UNKNOWN
Conditions: Chronic Kidney Diseases
Interventions: DIETARY_SUPPLEMENT: Resistant starch|BEHAVIORAL: Exercise|BEHAVIORAL: Starch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Glycaemic Responses to Cracker Snacks
Status: COMPLETED
Conditions: Glycaemic Response Measurements
Interventions: OTHER: Control Cracker Snack|OTHER: Experimental Cracker Snack 1|OTHER: Experimental Cracker Snack 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of Serum Calcium Level Between Preoperative Vitamin D and Non-vitamin D Regimen of Total Parathyroidectomy in End-stage Renal Failure Patients in Rajavithi Hospital
Status: COMPLETED
Conditions: End Stage Renal Disease
Interventions: DRUG: Calcitriol|DRUG: Alfacalcidol 0.5 MCG Oral Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Impact of Laparoscopic Versus Open Surgeries on the Incidence of Postoperative Deep Vein Thrombosis in Patients With Gastrointestinal Malignancy ---A Cohort Study
Status: UNKNOWN
Conditions: Deep Vein Thrombosis
Interventions: DEVICE: laparoscopic surgery|DEVICE: open surgery
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pediatric Trial of Indoximod with Chemotherapy and Radiation for Relapsed Brain Tumors or Newly Diagnosed DIPG
Status: RECRUITING
Conditions: Glioblastoma|Medulloblastoma|Ependymoma|Diffuse Intrinsic Pontine Glioma
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of S-1, S-1/CDDP, and 5-FU/CDDP for Advanced Gastric Cancer
Status: COMPLETED
Conditions: Gastric Cancer
Interventions: DRUG: S-1|DRUG: S-1 plus CDDP|DRUG: 5-FU plus CDDP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Relative Bioavailability Study of Metformin HCl 500 mg ER Tablets Under Non-fasting Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Metformin HCl 500 mg tablets, single dose|DRUG: CLUCOPHAGE® XR 500 mg tablets, single dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: A Trial to Evaluate the Safety and Tolerability of Brexpiprazole in the Treatment of Participants With Bipolar I Disorder.
Status: COMPLETED
Conditions: Bipolar I Disorder|Acute Mania
Interventions: DRUG: Brexpiprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Behavioral & Nutritional Treatment to Help CF Preschoolers Grow
Status: COMPLETED
Conditions: Cystic Fibrosis|Pancreatic Cystic Fibrosis
Interventions: BEHAVIORAL: Behavioral and Nutrition Treatment|BEHAVIORAL: Education and Attention Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Thermocoagulation in Drug Resistant Focal Epilepsy
Status: ACTIVE_NOT_RECRUITING
Conditions: Epilepsy|Seizures, Focal|Epilepsy Intractable|Epilepsies, Partial
Interventions: PROCEDURE: Radiofrequency thermocoagulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Seroprevalence of Chikungunya at the End of the First Chikungunya Outbreak in the French Antilles Within a Sample of Patients Treated for a HIV Infection
Status: COMPLETED
Conditions: HIV Infections|Chikungunya Virus Infection
Interventions: OTHER: Biological sample collection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Explore if Long-term Use of Mucinex Can Help With Symptoms in Patients With Stable Chronic Bronchitis.
Status: RECRUITING
Conditions: Chronic Bronchitis
Interventions: DRUG: Guafenesin tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Renal Insufficiency Following Contrast Media Administration Trial III
Status: UNKNOWN
Conditions: Contrast Nephropathy
Interventions: DEVICE: RenalGuard system™® (PLC Medical Systems, Inc. Franklin, MA, USA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Neoadjuvant Chemotherapy for the Treatment of Resectable Locally Advanced Colon Cancer
Status: UNKNOWN
Conditions: Colon Cancer
Interventions: DRUG: Postoperative chemotherapy|DRUG: Neoadjuvant chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Study Will Evaluate the Effect of AZD8683 in Patients With Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: DRUG: AZD8683, 50 mcg|DRUG: Placebo|DRUG: AZD8683, 200 mcg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Study to Evaluate the Cosmetic Appearance of Two Brands (Coopervision (CVI) vs. Competitor) of Color Soft Contact Lenses.
Status: COMPLETED
Conditions: Myopia
Interventions: DEVICE: Verde (Competitor-control)|DEVICE: Green (CVI-test)|DEVICE: Cinza (Competitor-control)|DEVICE: Grey (CVI-test)|DEVICE: Esmeralda (Competitor-control)|DEVICE: Jade (CVI-test)|DEVICE: Azul (Competitor-control)|DEVICE: Blue (CVI-test)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Inositol Stereoisomers to Treat Gestational Diabetes
Status: UNKNOWN
Conditions: Gestational Diabetes Mellitus
Interventions: DIETARY_SUPPLEMENT: Folic acid|DIETARY_SUPPLEMENT: Myo-inositol|DIETARY_SUPPLEMENT: D-Chiro-inositol|DIETARY_SUPPLEMENT: Myo-inositol plus D-chiro inositol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Pharmacokinetics and Clinical Activity of AZD0171 in Combination With Durvalumab and Chemotherapy in Locally Advanced or Metastatic Solid Tumours
Status: ACTIVE_NOT_RECRUITING
Conditions: Locally Advanced or Metastatic Solid Tumours
Interventions: DRUG: AZD0171|DRUG: Durvalumab|DRUG: Gemcitabine|DRUG: Nab-paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of an E-learning Intervention on Knowledge, Attitudes and Beliefs of Healthcare Professionals Managing Low Back Pain.
Status: COMPLETED
Conditions: Knowledge, Attitudes, Practice|Low Back Pain|Physical Therapy|Physicians
Interventions: OTHER: Experimental e-learning|OTHER: Traditional e-learning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Gemcitabine Monotherapy for Metastatic Breast Cancer After Anthracycline and Taxane Regimen
Status: COMPLETED
Conditions: Metastatic Breast Cancer
Interventions: DRUG: gemcitabine|DRUG: gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Tapentadol Extended Release Tablets in the Treatment of Moderate to Severe Pain in Subjects With Knee Osteoarthritis
Status: COMPLETED
Conditions: Osteoarthitis|Chronic Pain|Knee Pain
Interventions: DRUG: tapentadol HCl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Randomized Multicentre Study Comparing TEP With Lichtenstein Repair for Primary Inguinal Hernia
Status: COMPLETED
Conditions: Inguinal Hernia
Interventions: PROCEDURE: Open repair|PROCEDURE: Laparoscopic repair
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Abilify Therapy for Reducing Comorbid Substance Abuse
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder|Bipolar Disorder|Major Depressive Disorder|Anxiety Disorders|Substance Abuse
Interventions: DRUG: Aripiprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Individual and Populational Determinants on End Stage Renal Disease Children Quality of Life, During Dialysis Period.
Status: UNKNOWN
Conditions: Kidney Dysfunctions
Interventions: BEHAVIORAL: answering questionnaires
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: tDCS for Neurological Disability Among Subacute Stroke Survivors to Improve Multiple Domains in Quality of Life
Status: NOT_YET_RECRUITING
Conditions: Stroke|Stroke, Ischemic
Interventions: DEVICE: Anodal Transcranial Direct Current Stimulation (Anodal tDCS)|DEVICE: Sham Transcranial Direct Current Stimulation (tDCS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vaccination With Dendritic Cells Loaded With Brain Tumor Stem Cells for Progressive Malignant Brain Tumor
Status: COMPLETED
Conditions: Brain Tumor|Glioblastoma|Medulloblastoma|Ependymoma|Anaplastic Astrocytoma
Interventions: BIOLOGICAL: Dendritic Cells|DRUG: Imiquimod
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, and Effect of TMC207 and Efavirenz in Healthy Volunteers
Status: COMPLETED
Conditions: Tuberculosis|HIV
Interventions: DRUG: Efavirenz (EFV)|DRUG: TMC207
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Pharmacokinetics of Metronidazole 10% Ointment Applied Peri Anally in Healthy Volunteers and Patients With Perianal Crohn's Disease
Status: COMPLETED
Conditions: Perianal Crohns'
Interventions: DRUG: Metronidazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: |Primary Purpose: BASIC_SCIENCE
Clinical trial: Ipsilateral Transfer of Motor Skill From Upper to Lower Limb in Healthy Adults
Status: ACTIVE_NOT_RECRUITING
Conditions: Healthy
Interventions: BEHAVIORAL: Practice (UL)|BEHAVIORAL: Observation (SO)|BEHAVIORAL: Nature Observation (NO)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Apomorphine in Severe Brain-injured Patients
Status: RECRUITING
Conditions: Disorder of Consciousness
Interventions: DRUG: Apomorphine Hydrochloride 5mg/ml|OTHER: Sodium chloride 9mg/ml
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I/II Trial to Evaluate a Peptide Vaccine Plus Ipilimumab in Patients With Melanoma
Status: TERMINATED
Conditions: Melanoma
Interventions: DRUG: Ipilimumab|BIOLOGICAL: 6MHP
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Liposomal Tretinoin in Treating Patients With Recurrent or Refractory Hodgkin's Disease
Status: WITHDRAWN
Conditions: Lymphoma
Interventions: DRUG: Chemotherapy|DRUG: Tretinoin Liposome
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized Trial to Evaluate Efficacy and Safety of Intracavernosal Injection of Platelet-Rich Plasma Versus Phosphodiesterase Type-5 Inhibitors for Treatment of Erectile Dysfunction.
Status: ACTIVE_NOT_RECRUITING
Conditions: Erectile Dysfunction Following Radiation Therapy|Phosphodiesterase Inhibitor Adverse Reaction|Platelet- Rich Plasma (PRP)
Interventions: DRUG: P shot arm ( Autologous Platelet Rich Plasma)|DRUG: PDE5i arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cystoscopy Plus Urethral Dilatation Versus Cystoscopy Alone in Women With Overactive Bladder Syndrome and Impaired Voiding
Status: UNKNOWN
Conditions: Overactive Bladder Syndrome|Voiding Dysfunction
Interventions: PROCEDURE: Cystoscopy|PROCEDURE: Cystoscopy and urethral dilatation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Pecs II Block Versus Surgeon Infiltration for Open Subpectoral Biceps Tenodesis
Status: COMPLETED
Conditions: Tendonitis
Interventions: DRUG: Bupivacaine 20mL 0.5%|DRUG: Bupivacaine 20mL 0.25%|DRUG: Bupivacaine up to 15mL 0.25%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ankle Sprains and Corticospinal Excitability
Status: COMPLETED
Conditions: Ankle Sprain
Interventions: OTHER: High velocity, low amplitude stretch|OTHER: Slow, mobilization stretch|OTHER: Passive Positioning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Anti-inflammatory Effects of Topical Erythromycin and Clindamycin in Acne Patients
Status: RECRUITING
Conditions: Acne Vulgaris
Interventions: DRUG: Erythromycin 4% topical gel formulation|DRUG: Clindamycin 1% topical lotion formulation|DRUG: 70% topical ethanol solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: DAPRE Exercises Technique and CKC Exercises on Extensor Lag in Post Knee Stiffness
Status: COMPLETED
Conditions: Extensor Lag|Post-operative Knee Stiffness
Interventions: PROCEDURE: Daily adjustable progressive resistance exercises (DAPRE)|PROCEDURE: Close kinetic chain exercises (CKC).
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Use of Beta-agonists in Stable Severe Congestive Heart Failure
Status: UNKNOWN
Conditions: Ischemic Cardiomyopathy|Non-ischemic Cardiomyopathy|Heart Failure
Interventions: DRUG: Salbutamol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparisons of Nicotine-free Cigarettes, Extra Low Nicotine Cigarettes vs. Medicinal Nicotine
Status: COMPLETED
Conditions: Tobacco Dependence
Interventions: DRUG: Nicotine free cigarettes|DRUG: Extra-low nicotine cigarettes|DRUG: Nicotine Lozenge
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Single Oral Dose of BeneFlax to Healthy Young and Older Adults
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Hypercholesterolemia
Interventions: OTHER: BeneFlax - 38% secoisolariciresinol diglucoside (SDG)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: REZŪM vs. Dual Drug Therapy for Symptomatic Benign Prostatic Hyperplasia in Sexually Active Men
Status: RECRUITING
Conditions: Benign Prostatic Hyperplasia (BPH)
Interventions: DEVICE: REZŪM|DRUG: alpha blocker and 5-alpha reductase inhibitor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Effectiveness of Saroglitazar 4 mg in Patients With NAFLD With Comorbidities
Status: RECRUITING
Conditions: NAFLD|Obesity|Type 2 Diabetes|Dyslipidemias|Metabolic Syndrome
Interventions: DRUG: Saroglitazar
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: In Vivo Confocal Microscopy for Pigmented Lesion Diagnosis
Status: COMPLETED
Conditions: Skin Cancer|Melanoma|Lentigo Maligna
Interventions: DEVICE: Reflectance confocal microscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC