pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Sensitivity and Specificity of the Modified Helicobacter Test INFAI
Status: WITHDRAWN
Conditions: Dyspepsia|GERD
Interventions: DIAGNOSTIC_TEST: Helicobacter Pylori Diagnostic|DEVICE: Vital signs measurments|DIAGNOSTIC_TEST: endoscopy|DRUG: Nexium Pill
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Efficacy and Safety of CSJ117 in Patients With Severe Uncontrolled Asthma
Status: TERMINATED
Conditions: Asthma
Interventions: DRUG: CSJ117|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Low Concentrate Detergents Versus Hypertonic Glucose for the Treatment of Telangiectasia
Status: COMPLETED
Conditions: Sclerotherapy
Interventions: PROCEDURE: Sclerotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Nebivolol on the Blood Flow in Hearts of Adults With High Blood Pressure and Abnormal Filling of Heart
Status: COMPLETED
Conditions: Hypertension|Left Ventricular Diastolic Dysfunction
Interventions: DRUG: Nebivolol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Palatal Pre-sutures in Connective Tıssue Graft Surgery
Status: COMPLETED
Conditions: Suture, Complication|Gingival Recession|Bleeding Hemorrhage
Interventions: PROCEDURE: Suture|PROCEDURE: No Suture CTG -Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Lidocaine Infusion on Neuraxial Opioid-induced Pruritus After Cesarean Section
Status: COMPLETED
Conditions: Lidocaine Infusion|Neuraxial Opioid|Pruritus|Cesarean Section
Interventions: DRUG: Lidocaine|OTHER: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Improve Mental Health and Emotional Labor Among Nurses Who Care the End-of-life Patients
Status: UNKNOWN
Conditions: End-of-life|Depression, Anxiety
Interventions: BEHAVIORAL: cognitive behavioural therapy|BEHAVIORAL: mindfulness-based therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Blood Stem Cell Transplant With Low Dose Chemotherapy for Relapsed Follicular Non-Hodgkin's Lymphoma (BMT CTN 0701)
Status: COMPLETED
Conditions: Lymphoma, Non-Hodgkin
Interventions: BIOLOGICAL: Hematopoietic Stem Cell Transplant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Applications of Blood Flow Restriction and Rehabilitation Outcomes
Status: RECRUITING
Conditions: Knee Pain Chronic|Anterior Knee Pain Syndrome|Patellofemoral Pain Syndrome|Rotator Cuff Impingement Syndrome|Rotator Cuff Tendinosis
Interventions: OTHER: Blood flow restriction (BFR) with low load resistance training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Krill Oil and Muscle Weakness in Type 2 Diabetes
Status: RECRUITING
Conditions: Diabetes Mellitus, Type 2
Interventions: DIETARY_SUPPLEMENT: Krill Oil|DIETARY_SUPPLEMENT: Vegetable Oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Breathe NIOV System on Work of Breathing in Chronic Obstructive Lung Disease Patients
Status: COMPLETED
Conditions: Chronic Obstructive Lung Disease
Interventions: DEVICE: Breathe NIOV Ventilator
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Tight Control of Gouty Arthritis Compared to Usual Care
Status: NOT_YET_RECRUITING
Conditions: Gout
Interventions: OTHER: Treat-to-target|OTHER: Treat-to-flare
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study to Evaluate the Effects of Cytochrome P450 (CYP) 3A4 Inducer Carbamazepine on Tavapadon Pharmacokinetics in Healthy Adult Participants
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: DRUG: Tavapadon|DRUG: Carbamazepine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Peace of Mind and Body Project: Treatment Development of Yoga for Anger Management in Incarcerated Adults
Status: COMPLETED
Conditions: Anger|Aggression
Interventions: BEHAVIORAL: Hatha Yoga|BEHAVIORAL: Health Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Stent Retriever's(TonbridgeMT) Endovascular Therapy for Acute Ischemic Stroke(AIS)
Status: COMPLETED
Conditions: Ischemic Stroke
Interventions: DEVICE: stent retriever(TonbridgeMT)|DEVICE: Solitaire™
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluating Sirolimus to Treat Autoimmune Blistering Dermatosis Pemphigus
Status: TERMINATED
Conditions: Pemphigus
Interventions: DRUG: Sirolimus (formerly known as Rapamycin)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Outcomes in Lower Pole Kidney Stone Management Using Mini-PCNL Compared With Retrograde Intra Renal Surgery
Status: COMPLETED
Conditions: Kidney Stone
Interventions: PROCEDURE: Mini-PCNL|PROCEDURE: RIRS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dapagliflozin Effect on Rheumatic Mitral Stenosis
Status: NOT_YET_RECRUITING
Conditions: Rheumatic Heart Disease|Heart Failure|Mitral Stenosis
Interventions: DRUG: Dapagliflozin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness and Safety of Tenofovir Alafenamide in the Treatment of Chronic Hepatitis B Patients With Mildly Elevated Alanine Aminotransferase and Significant Liver Injury.
Status: RECRUITING
Conditions: Chronic Hepatitis b
Interventions: DRUG: Tenofovir Alafenamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lung Ultrasound and Alveolar Recruitment in Mechanically Ventilated Infants
Status: COMPLETED
Conditions: Pulmonary Atelectasis
Interventions: DEVICE: Lung ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation Of The Efficacy And Safety Of The Doxasozin Gastrointestinal Therapeutic System (GITS) In Patients With Prostate Enlargement
Status: COMPLETED
Conditions: Prostate
Interventions: DRUG: Doxazosin mysylate GITS
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized Controlled Trial of Meditation Compared to Exposure Therapy and Education Control on PTSD in Veterans
Status: COMPLETED
Conditions: Post-traumatic Stress Disorder
Interventions: BEHAVIORAL: Transcendental Meditation|BEHAVIORAL: Prolonged Exposure|BEHAVIORAL: Educational control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Economic Evaluation of Three Populational Screening Strategies for Cervical Cancer
Status: UNKNOWN
Conditions: Uterine Cervical Neoplasms
Interventions: OTHER: Different alternatives to improve the coverage of the populational screening programmes of cervical cancer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Evaluation of Energy Drink Consumption on ECG and Hemodynamic Parameters in Young Healthy Volunteers
Status: COMPLETED
Conditions: Hemodynamic Effects of Energy Drink|Electrocardiograph Effects of Energy Drinks
Interventions: DIETARY_SUPPLEMENT: Energy Drink|DIETARY_SUPPLEMENT: Active Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: A Randomized, Double-blind, Multicenter, Sham-controlled, Safety and Efficacy Study of Conbercept in Patients With mCNV
Status: UNKNOWN
Conditions: Choroid Neovascularization Secondary to Degenerative Myopia
Interventions: DRUG: conbercept, Fixed|DRUG: conbercept, PRN|OTHER: sham injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Natural History of Oculomotor Neurophysiology in Ataxic and Pre-ataxic Carriers of SCA3/MJD
Status: UNKNOWN
Conditions: Spinocerebellar Ataxia Type 3|Machado-Joseph Disease
Interventions: DIAGNOSTIC_TEST: Video-oculography|DIAGNOSTIC_TEST: Clinical Scales|DIAGNOSTIC_TEST: Genotyping
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Bioequivalence Study of Empagliflozin & Metformin HCL From Empagliform 12.5/1000 mg F.C.T (Hikma Pharma, Egypt) and Synjardy 12.5/1000 mg F.C.T (Boehringer Ingelheim International GmbH, Germany)
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Empagliflozin & Metformin (Test)|DRUG: Empagliflozin & Metformin (Reference)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Loco/Regional Anaesthesia Evaluation in Laparoscopic Hernioplasty
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: PROCEDURE: Novel local infiltration technique|PROCEDURE: TAP block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Adalimumab on Preventing Post-chirurgic Recurrence on Crohn´s Disease
Status: COMPLETED
Conditions: Crohn´s Disease
Interventions: DRUG: Metronidazole|DRUG: Metronidazole|DRUG: Azathioprine|DRUG: Adalimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: DSAP Treatment Comparison: 2% Lovastatin/ 2% Cholesterol vs 2% Lovastatin Alone
Status: COMPLETED
Conditions: Actinic Porokeratosis
Interventions: DRUG: Lovastatin 2%, 2% Cholesterol Cream|DRUG: Lovastatin 2% Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Levetiracetam for Neuroprotection Against Corticosteroid-induced Hippocampal Dysfunction: A Proof of Concept Study
Status: COMPLETED
Conditions: Memory Loss Associated With Corticosteroid Use|Manic State Associated With Corticosteroid Use
Interventions: DRUG: Levetiracetam, Keppra
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Clinical Efficacy of Telmisartan in Reducing Cardiac Remodeling Among Obese Patients With Hypertension
Status: UNKNOWN
Conditions: Hypertension
Interventions: DRUG: telmisartan|DRUG: amlodipine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Immunosuppressive Therapy for IgA Nephropathy With Stage 3 or 4 CKD
Status: RECRUITING
Conditions: Glomerulonephritis, IGA
Interventions: DRUG: Prednisolone|DRUG: Prednisolone plus Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Civamide Patch in Treatment of Postherpetic Neuralgia and Post-Incisional Neuralgia
Status: COMPLETED
Conditions: Postherpetic Neuralgia
Interventions: DRUG: Civamide Patch
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Trial of Immunotherapeutic HPV Vaccine PRGN-2009 With Pembrolizumab Before Standard Treatment in Subjects With Newly Diagnosed HPV-Associated Oropharyngeal Cancer
Status: RECRUITING
Conditions: Oropharyngeal Squamous Cell Carcinoma (SCC)
Interventions: BIOLOGICAL: PRGN-2009|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of 8-weeks of Bovine Colostrum and Soy Protein Supplementation in Rugby Players
Status: COMPLETED
Conditions: Exercise Performance|Body Composition
Interventions: DIETARY_SUPPLEMENT: Bovine Colostrum|DIETARY_SUPPLEMENT: Soy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Telerehabilitation for Aphasia (TERRA)
Status: RECRUITING
Conditions: Aphasia|Stroke|Stroke Rehabilitation
Interventions: BEHAVIORAL: Semantically-focused therapy tasks|BEHAVIORAL: Phonologically-focused therapy tasks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Capecitabine (Xeloda) in the Adjuvant Treatment of Participants With Resected Colon Cancer
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GlycoCholic Acid Treatment for Patients With Inborn Errors in Bile Acid Synthesis
Status: COMPLETED
Conditions: Bile Acid Synthesis Defect|Inborn Error of Bile Acid Metabolism|Inborn Error of Bile Acid Conjugation
Interventions: DRUG: Glycocholic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Piperacillin/Tazobactam Versus ceftriAxone and Metronidazole for Children With Perforated Appendicitis (ALPACA)
Status: NOT_YET_RECRUITING
Conditions: Appendicitis Perforated
Interventions: DRUG: Piperacillin/tazobactam|DRUG: Normal saline|DRUG: CefTRIAXone Injection|DRUG: Metronidazole Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Three-Dimensional Printing of Patient-Specific Titanium Plates in Jaw Surgery: A Pilot Study
Status: COMPLETED
Conditions: Mandibular Neoplasms|Maxillary Neoplasms|Dentofacial Deformities|Maxillofacial Injuries
Interventions: DEVICE: 3D-printed patient-specific titanium plates
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Efficacy, Safety, and Pharmacokinetic Profiles of REGN3500 Administered to Adult Patients With Moderate-to-Severe Atopic Dermatitis
Status: TERMINATED
Conditions: Atopic Dermatitis
Interventions: DRUG: REGN3500|DRUG: REGN3500-Matching Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Radiofrequency for Chronic Post-mastectomy Pain: is it Better to Target Intercostal Nerves or Corresponding Dorsal Root Ganglia?
Status: COMPLETED
Conditions: Post-Mastectomy Chronic Pain Syndrome
Interventions: PROCEDURE: radiofrequency|PROCEDURE: radiofrequency
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nicotine Replacement Therapy for Smoking Cessation in Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder
Interventions: DRUG: bupropion, transdermal nicotine patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Impact of Gut Microbiota and Tryptophan Metabolites on Acute Pain in Lumbar Disc Herniation Surgery Patients
Status: COMPLETED
Conditions: Microbial Substitution|Tryptophan Metabolism Alterations|Postoperative Pain, Acute
Interventions: PROCEDURE: Pain Perception in Patients Undergoing Lumbar Disc Herniation Surgery
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Ledipasvir/Sofosbuvir for Hepatitis B Virus Infection
Status: COMPLETED
Conditions: Hepatitis B
Interventions: DRUG: Ledipasvir 90 MG / Sofosbuvir 400 MG Oral Tablet [Harvoni]|DRUG: Sofosbuvir 400 MG [Sovaldi]|DRUG: Ledipasvir 90 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Monocentric Study on Acetabulum Patient-specific Pin Drilling Guides
Status: TERMINATED
Conditions: Osteoarthritis, Hip
Interventions: PROCEDURE: THR with conventional technique|PROCEDURE: THR with Acetabular Cup Orientation Guides (ACOG)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prehabilitation & Rehabilitation in Oncogeriatrics: Adaptation to Deconditioning Risk and Accompaniment of Patients' With Cancer
Status: COMPLETED
Conditions: Old Injury
Interventions: BEHAVIORAL: standardized geriatric intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Safety and Efficacy of Tofacitinib for Chronic Granulomatous Disease With Inflammatory Complications
Status: ENROLLING_BY_INVITATION
Conditions: Chronic Granulomatous Disease|Inflammatory Gastrointestinal Disease|Inflammatory Skin Disease|Inflammatory Lung Disease
Interventions: DRUG: XELJANZ (tofacitinib)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Plasma Metabolic Biomarkers for Multi-Cancer Diagnosis
Status: RECRUITING
Conditions: Lung Cancer|Breast Cancer|Colorectal Cancer|Thyroid Cancer|Gastric Cancer|Cervical Cancer|Liver Cancer|Pancreatic Cancer|Cholangiocarcinoma|Prostate Cancer|Esophageal Cancer|Ovarian Cancer|Renal Cell Carcinoma
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pilot Study of Olanzapine and Aprepitant to Prevent Nausea and Vomiting in Children Receiving Chemotherapy
Status: COMPLETED
Conditions: Chemotherapy Induced Nausea and Vomiting
Interventions: DRUG: Olanzapine|DRUG: Aprepitant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effects on Children and Parents of Educating Parents About Ways to Play With Babies
Status: COMPLETED
Conditions: Infant Development|Developmental Delay
Interventions: OTHER: Enriched Education Program|OTHER: Typical Education Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effects of Duloxetine on Norepinephrine
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: Duloxetine|DRUG: Escitalopram|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: A Study to Determine Whether Chemotherapy and Atezolizumab is Better Than Chemotherapy, Bevacizumab and Atezolizumab in Patients With Advanced Liver Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Combined Hepatocellular Carcinoma and Cholangiocarcinoma|Stage III Liver Cancer|Stage IV Liver Cancer
Interventions: BIOLOGICAL: Atezolizumab|BIOLOGICAL: Bevacizumab|PROCEDURE: Biospecimen Collection|DRUG: Cisplatin|PROCEDURE: Computed Tomography|PROCEDURE: Conventional Magnetic Resonance Imaging|DRUG: Gemcitabine Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of Neoadjuvant Chemotherapy With Chemoradiation Therapy for Nasopharyngeal Carcinoma
Status: UNKNOWN
Conditions: Chemoradiation|Nasopharyngeal Carcinoma
Interventions: DRUG: PF (cisplatin and 5-fluorouracil) group|DRUG: TPF (docetaxel plus cisplatin and 5-fluorouracil) group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Genotropin Treatment In Very Young Children Born Small For Gestational Age
Status: COMPLETED
Conditions: Infant, Small for Gestational Age
Interventions: DRUG: Genotropin (PN-180,307) Somatropin|DRUG: Control-no treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Imaging of Radiolabeled White Blood Cells in Patients With Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Lymphoma|Small Intestine Cancer
Interventions: PROCEDURE: radionuclide imaging|RADIATION: indium In 111-labeled autologous peripheral blood mononuclear cells|RADIATION: indium In 111-labeled autologous polymorphonuclear leukocytes
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Repeat Insult Patch Test for Daily Advance Cetaphil Moisturizing Lotion
Status: COMPLETED
Conditions: Skin Irritation
Interventions: OTHER: Cetaphil Moisturizing Lotion Daily Advance
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Breaking "Bad Rest" Study: Interrupting Sedentary Time to Reverse Frailty Levels in Acute Care
Status: COMPLETED
Conditions: Sedentary Lifestyle
Interventions: BEHAVIORAL: Sedentary behavior reduction intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy of the New Closure Device in Improving Patient Compliance in Treatment of Hypertension With Valsartan+/-Hydrochlorothiazide (HCTZ) at 6 Months
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Valsartan+/- Hydrochlorothiazide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PGC-1 & Muscle Mitochondrial Dysfunction in Diabetes
Status: TERMINATED
Conditions: Diabetes|Obesity
Interventions: BEHAVIORAL: Pre-study dietary and exercise instruction.|PROCEDURE: Screening examination and oral glucose tolerance test|PROCEDURE: Euglycemic clamp|PROCEDURE: VO2max.|BEHAVIORAL: Acute exercise bout|PROCEDURE: Percutaneous needle muscle biopsies
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Prospective Randomized Trial Evaluating Mandatory Second Look Surgery With HIPEC and CRS vs. Standard of Care in Subjects at High Risk of Developing Colorectal Peritoneal Metastases
Status: WITHDRAWN
Conditions: Colorectal Carcinoma|Peritoneal Carcinomatosis
Interventions: PROCEDURE: Laparotomy+ HIPEC +/- CRS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Infectivity, Safety and Immunogenicity of Two Recombinant, Live-Attenuated, B/HPIV3 Vectored Vaccines Expressing the Fusion Glycoprotein of HMPV Delivered by Nasal Spray to HPIV3-Seropositive Children 24 to <60 Months of Age
Status: RECRUITING
Conditions: Human Metapneumovirus|Human Parainfluenza Virus Type 3
Interventions: BIOLOGICAL: B/HPIV3/HMPV-PreF-A vaccine|BIOLOGICAL: B/HPIV3/HMPV-F-B365 vaccine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of Different Teaching Methods in Increasing Nursing Students' Competencies for Safe Use of Medical Devices
Status: NOT_YET_RECRUITING
Conditions: Nurse's Role
Interventions: OTHER: Teach-back|OTHER: Video-assisted teaching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Pain Prevention During Propofol Infusion in Pediatric: Hypnoanalgesia of the Hand Versus Lidocaine.
Status: COMPLETED
Conditions: Pain
Interventions: PROCEDURE: Magic glove hypnosis technique|DRUG: lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Effectiveness Evaluation for Pathway to Healthy Aging (Path-HA) Care on Health Status of Older Adults
Status: RECRUITING
Conditions: Ageing Well
Interventions: BEHAVIORAL: Pathway to Healthy Aging care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Cartilage Autograft Implantation System (CAIS) for the Repair of Knee Cartilage Through Cartilage Regeneration
Status: TERMINATED
Conditions: Defect of Articular Cartilage|Osteochondritis Dissecans
Interventions: PROCEDURE: Microfracture|DEVICE: Cartilage Autograft Implantation System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase Ib/2 Clinical Study of Fruquintinib Combined With Paclitaxel in the Treatment of Advanced Gastric Cancer
Status: COMPLETED
Conditions: Gastric Cancer
Interventions: DRUG: fruquintinib+paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Maximum Tolerated Dose (MTD) of Liposomal Doxorubicin in Combination With Seliciclib for Patients With Metastatic Triple Negative Breast Cancer (TNBC)
Status: WITHDRAWN
Conditions: Breast Cancer
Interventions: DRUG: Liposomal Doxorubicin|DRUG: Seliciclib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Kisspeptin Administration in the Adult
Status: COMPLETED
Conditions: Hypogonadotropic Hypogonadism|Kallmann Syndrome|GnRH Deficiency|PCOS|Polycystic Ovarian Syndrome|Hyperprolactinemia
Interventions: DRUG: kisspeptin 112-121|DRUG: GnRH
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Paracetamol vs Ibuprofen for PDA Closure in Preterm Infants.
Status: SUSPENDED
Conditions: Ductus Arteriosus Patent|Respiratory Distress Syndrome
Interventions: DRUG: Intravenous paracetamol|DRUG: Intravenous ibuprofen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Predictors of Ovarian Reserve in Infertile Women
Status: UNKNOWN
Conditions: Ovarian Reserve
Interventions: DRUG: human menopausal gonadotropin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation of ABEMACICLIB Monotherapy in Patients With Locally Advanced/Metastatic Head and Neck Cancer After Failure of Platinum and Cetuximab or Anti-EGFR-based Therapy and Harboring an Homozygous Deletion of CDKN2A, and/or an Amplification of CCND1 and/or of CDK6
Status: COMPLETED
Conditions: Head and Neck Cancer|Advanced Cancer|Metastatic Cancer
Interventions: DRUG: Abemaciclib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Multimedia Exposure in Patients Transferred to Hospital Suffering From Acute Myocardial Infarction
Status: NOT_YET_RECRUITING
Conditions: Myocardial Infarction, Acute|Anxiety State|Emergencies
Interventions: OTHER: Exposition to multimedia content
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Sugammadex Compared With Neostigmin/Atropin for Neuromuscular Block Reversal in Patients With Obstructive Sleep Apnea
Status: COMPLETED
Conditions: Obstructive Sleep Apnea
Interventions: DRUG: Sugammadex|DRUG: Neostigmine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Cervical Distraction Versus Cervical Traction Techniques on Upper Cervical Pain
Status: COMPLETED
Conditions: Neck Pain
Interventions: OTHER: conventional physical therapy with distraction technique|OTHER: conventional physical therapy with traction technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Alzheimer's Caregiver Coping: Mental and Physical Health
Status: COMPLETED
Conditions: Alzheimer Disease|Alzheimer Dementia|Alzheimer's Disease|Dementia
Interventions: BEHAVIORAL: Behavioral Activation|BEHAVIORAL: Information and Support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Genistein Stimulates Insulin Sensitivity Through Gut Microbiota
Status: COMPLETED
Conditions: Metabolic Syndrome|Obesity
Interventions: DIETARY_SUPPLEMENT: genistein|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Home-Based Action Observation Training for Chewing and Swallowing Function
Status: RECRUITING
Conditions: Cerebral Palsy|Chewing Disease|Action Obervation Training
Interventions: OTHER: Chewing Exercise Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Creation of a Patient Database for Silicon Patient Simulation, Glucose Sensor Variability and Pharmacokinetic Study of Debiotech Jewelpump
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: DEVICE: Dexcom7|DEVICE: Dexcom7
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exercise Program During Chemotherapy in Metastatic Colorectal Cancer
Status: TERMINATED
Conditions: Stage IV Colorectal Cancer
Interventions: BEHAVIORAL: Exercise Intervention|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Dexamedatomidine vs. Dexamethasone in Rhomboidal Intercostal Plain Block and Subserratus Block in Breast Surgery
Status: UNKNOWN
Conditions: Postoperative Pain, Acute
Interventions: PROCEDURE: Rhomboid Intercostal and Sub-Serratus block technique (RISS)|PROCEDURE: General Anaesthesia|DRUG: dexamedatomidine|DRUG: dexamethasone|DRUG: saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Validation Study of RETINA-AI Galaxy™ v2.0, an Automated Diabetic Retinopathy Screening Device
Status: COMPLETED
Conditions: Diabetes|Diabetic Retinopathy|Diabetic Macular Edema|Diabetic Eye Problems
Interventions: DIAGNOSTIC_TEST: Color fundus photograph|DIAGNOSTIC_TEST: Optical Coherence Tomography (OCT) of the retina|DRUG: Mydriatic Agent
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Ultrasound Guided Local Anesthetic Field Block (A Five Step Procedure) for Open Inguinal Hernia Repair
Status: COMPLETED
Conditions: Inguinal Hernia
Interventions: PROCEDURE: US guided five step field block|PROCEDURE: Spinal anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: FOXP1 Syndrome: The Seaver Autism Center for Research and Treatment is Characterizing FOXP1-related Neurodevelopmental Disorders Using Genetic, Medical, and Neuropsychological Measures.
Status: RECRUITING
Conditions: FOXP1|Mental Retardation With Language Impairment and With or Without Autistic Features|Autism Spectrum Disorder
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Inhaled Nitric Oxide for Preterm Infants With Severe Respiratory Failure
Status: TERMINATED
Conditions: Infant, Newborn|Infant, Low Birth Weight|Infant, Small for Gestational Age|Infant, Premature|Respiratory Distress Syndrome (RDS)|Sepsis|Pneumonia|Hypertension, Pulmonary
Interventions: DRUG: Inhaled nitric oxide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of GRAd-COV2 for the Prevention of COVID-19 in Adults
Status: COMPLETED
Conditions: Covid19
Interventions: BIOLOGICAL: GRAd-COV2|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Antibiotic Therapy for Early Onset Neonatal Sepsis
Status: RECRUITING
Conditions: Early Onset Neonatal Sepsis
Interventions: DRUG: Piperacillin and tazobactam, azlocillin, latamoxef, meropenem, vancomycin，cefotaxime
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of LY2784544 in Participants With Myeloproliferative Neoplasms
Status: ACTIVE_NOT_RECRUITING
Conditions: Neoplasms, Hematologic
Interventions: DRUG: 120 mg LY2784544
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Minimal Effective Dose of Sucrose for Pain Relief in Neonates After Minor Procedure
Status: COMPLETED
Conditions: Post Procedural Pain Management in Neonates
Interventions: DRUG: 0.2 ml dose of sucrose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: LMY-920 for Treatment of Relapsed or Refractory Myeloma
Status: RECRUITING
Conditions: Multiple Myeloma, Refractory|Multiple Myeloma in Relapse
Interventions: BIOLOGICAL: Autologous CAR-T cell therapy expressing the BAFF-ligand.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Glucose Metabolism in the Immediate and Short Term Follow up After Bariatric Surgery
Status: COMPLETED
Conditions: Diabetes|Gastric Bypass
Interventions: PROCEDURE: Mixed Meal Tolerance test, Hyperglycemic clamp
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Inactivated Influenza Vaccine Delivered by Microneedle Patch or by Hypodermic Needle
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Inactivated influenza vaccine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Denosumab and Nivolumab Combination as 2d-line Therapy in Stage IV NSC Lung Cancer With Bone Metastases (DENIVOS)
Status: ACTIVE_NOT_RECRUITING
Conditions: Carcinoma, Non-Small-Cell Lung|Bone Metastases
Interventions: DRUG: Denosumab-nivolumab combination
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized Trial of Pembrolizumab & Radiotherapy Versus Radiotherapy in High-Risk Soft Tissue Sarcoma of the Extremity
Status: ACTIVE_NOT_RECRUITING
Conditions: Soft Tissue Sarcoma of the Extremity
Interventions: DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Biscuits Containing Red Palm Oil on School Children With Vitamin A Deficiency in West and East Malaysia
Status: UNKNOWN
Conditions: Vitamin A Deficiency in Children
Interventions: DIETARY_SUPPLEMENT: red palm shortening group|DIETARY_SUPPLEMENT: palm shortening group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Single-arm Study to Evaluate the Safety and Efficacy of Sunitinib, in Subjects With RET Fusion Positive or FGFR2 Amplification, Refractory Solid Tumors
Status: COMPLETED
Conditions: Refractory Solid Tumors
Interventions: DRUG: sunitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An International Study of the Safety and Tolerability of Corlux for Psychotic Symptoms in Psychotic Major Depression
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: Mifepristone|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Safety of Amantadine Hydrochloride (HCl) Intravenous (IV) Solution (MR-301) in Patients With Severe Traumatic Brain Injury (TBI).
Status: RECRUITING
Conditions: Traumatic Brain Injury
Interventions: DRUG: Amantadine Hydrochloride|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Short and Fast Step Test: Feasibility, Validity and Tolerance of a Functional Evaluation Test of Lactic Anaerobic Capacities in Patients With Coronary Artery Disease
Status: COMPLETED
Conditions: Coronary Artery Disease Without Heart Failure
Interventions: OTHER: Short and fast step test without measurement of pulmonary gas exchange|BIOLOGICAL: glucose meter|OTHER: ECG / heart rate|OTHER: questionnaires|OTHER: Short and fast step test with measurement of pulmonary gas exchange
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: RIPC During Free Flap With Preoperative Radiotherapy
Status: COMPLETED
Conditions: Ischemic Reperfusion Injury|Other Reconstructive Surgery|Radiotherapy
Interventions: OTHER: remote ischemic preconditioning (RIPC)|OTHER: Sham-RIPC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Evolocumab on Carotid Artery Atherosclerotic Plaque Morphology Prior to Carotid EndArterectomy
Status: UNKNOWN
Conditions: Carotid Artery Stenosis|Asymptomatic Carotid Artery Stenosis
Interventions: DRUG: Evolocumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Visual Outcome, Cylinder Correction and Patient Satisfaction After Implantation of AT LISA Tri Toric 939MP Intraocular Lenses
Status: COMPLETED
Conditions: Cataract
Interventions: DEVICE: AT LISA tri toric 939MP
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Gabapentin, Ketamine and Dexamethasone on Pain and Opioid Requirements After Hip Surgery
Status: TERMINATED
Conditions: Pain, Postoperative
Interventions: DRUG: Gabapentin + dexamethasone + ketamine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Objectives of This Study Are Study the Immunogenicity and Safety of the Flu-M [Inactivated Split Influenza Vaccine], vs. the Ultrix® Inactivated Split Influenza Vaccine, in Volunteers Who Are Over 60 Years Old
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Flu-M [Inactivated split influenza vaccine]|BIOLOGICAL: Inactivated Split Influenza Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Safety of LAM561 Added to Standard of Care in Newly-diagnosed Glioblastoma Patients
Status: COMPLETED
Conditions: Glioblastoma (GBM)
Interventions: DRUG: LAM561|RADIATION: RT|DRUG: TMZ
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics (PK) and Metabolism of FTY720 in Patients With Severe Renal Impairment and Healthy Matched Subjects.
Status: COMPLETED
Conditions: Renal Insufficiency
Interventions: DRUG: fingolimod (FTY720)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effects of Multiple Concussions in Retired NHL Players
Status: TERMINATED
Conditions: Cognitive Deficits|Proprioceptive Disorders
Interventions: OTHER: Sensory Organization Test|GENETIC: Biomarkers|OTHER: Conners' Adult ADHD Rating Scale (CAARS)|OTHER: Depression Scale|OTHER: Cognitive Assessment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Using CBPR to Engage Hazardous Drinking Women in the HIV Prevention and Care Continuum
Status: ACTIVE_NOT_RECRUITING
Conditions: HIV|Alcohol; Harmful Use|Mental Health Disorder
Interventions: BEHAVIORAL: CBI-CC with peer navigation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Probiotics Improves the Endurance and Explosiveness Exercise Performance on Healthy Human.
Status: COMPLETED
Conditions: Exercise Performance
Interventions: DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: Probiotic 1,Lactococcus lactis subsp. lactis, LY-66|DIETARY_SUPPLEMENT: Probiotic 2,Lactobacillus plantarum, PL-02|DIETARY_SUPPLEMENT: Probiotic 3,Lactococcus lactis subsp. lactis, LY-66+Lactobacillus plantarum, PL-02
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of FCN-011 in Patients With Advanced Solid Tumor（Phase I）and NTRK Fusion Positive Advanced Solid Tumor （Phase II）
Status: UNKNOWN
Conditions: Advanced Solid Tumor
Interventions: DRUG: FCN-011
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: T-regulatory Cells in ALS
Status: UNKNOWN
Conditions: ALS (Amyotrophic Lateral Sclerosis)
Interventions: BIOLOGICAL: Monthly autologous Treg cells infusions + 3 times per week Interleukin-2 injections|OTHER: Monthly placebo infusions + 3 times per week placebo injections|BIOLOGICAL: Monthly autologous Treg cells infusions + 3 times per week Interleukin-2 injections
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dry Needling for Shoulder Adhesive Capsulitis
Status: ENROLLING_BY_INVITATION
Conditions: Shoulder Adhesive Capsulitis|Shoulder Pain|Frozen Shoulder
Interventions: OTHER: Dry needling|OTHER: Sham Dry Needling|OTHER: Therapeutic Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Cabozantinib and Pembrolizumab in Metastatic Pancreas
Status: ACTIVE_NOT_RECRUITING
Conditions: Pancreatic Cancer
Interventions: DRUG: Cabozantinib|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Assess the Safety, Tolerability, Pharmacokinetics and Pharmakodynamics of AZD2820 After Multiple Ascending Doses
Status: TERMINATED
Conditions: Obesity
Interventions: DRUG: AZD2820|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Augmentation of Psychotherapy With D-Cycloserine in Agoraphobia
Status: COMPLETED
Conditions: Agoraphobia
Interventions: BEHAVIORAL: CBT|DRUG: D-Cycloserine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tranexamic Acid Versus Adrenaline for Controlling Iatrogenic Endobronchial Bleeding
Status: COMPLETED
Conditions: Bleeding|Hemoptysis
Interventions: DRUG: Tranexamic acid|DRUG: Adrenaline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Home-based Gait Rehabilitation Service Using the Insole-type Gait Analysis Device for Children With Cerebral Palsy
Status: NOT_YET_RECRUITING
Conditions: Gait Disorders, Neurologic|Cerebral Palsy
Interventions: DEVICE: Insole wearing
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH