pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Auricular Acupuncture for Primary Insomnia
Status: COMPLETED
Conditions: Primary Insomnia
Interventions: OTHER: auricular acupuncture(AA)|OTHER: placebo AA|DRUG: Eszopiclone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ensitrelvir for Viral Persistence and Inflammation in People Experiencing Long COVID
Status: RECRUITING
Conditions: Long COVID|Post Acute Sequelae of COVID-19|Post-Acute COVID-19
Interventions: DRUG: Ensitrelvir|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The MATRIX OCT Substudy
Status: UNKNOWN
Conditions: Acute Myocardial Infarction, Coronary Stent Thrombosis, Antithrombotic Therapy
Interventions: DEVICE: Optical Coherence Tomography of the infarct related artery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Orthodontic Extrusion of High Risk Impacted Mandibular Third Molar
Status: COMPLETED
Conditions: Inferior Alveolar Nerve Injuries
Interventions: PROCEDURE: Orthodontic extrusion of the impacted mandibular third molar by using the maxillary miniscrew and cross arch elastic power chain as a temporary anchorage device before extraction
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Application of MI-BCI Combined With tDCS in Early Rehabilitation After Anterior Cruciate Ligament Reconstruction
Status: COMPLETED
Conditions: Anterior Cruciate Ligament Injuries
Interventions: DEVICE: MI-BCI combined with tDCS treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety of Single Doses of SAR113945 and Efficacy and Safety of a New Formulation Given Into the Knee in Osteoarthritis Patients / Part I
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: DRUG: SAR113945|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Short Term Effects and Risks of Physical Exercise in Subjects With Hypohidrotic Ectodermal Dysplasia
Status: COMPLETED
Conditions: X-Linked Hypohidrotic Ectodermal Dysplasia|Exercise-induced Rise of Body Temperature
Interventions: DEVICE: Skin cooling devices
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: TES of Artemether-lumefantrine for Pf and Chloroquine for Pv in the Philippines From 2013-2014
Status: COMPLETED
Conditions: Malaria|Falciparum Malaria|Vivax Malaria|Malaria Recrudescence
Interventions: DRUG: Arthemeter-lumefantrine|DRUG: Chloroquine|DRUG: Primaquine
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of the Body Slimming Effect of TCI904
Status: COMPLETED
Conditions: Body Weight|Metabolic Syndrome
Interventions: DIETARY_SUPPLEMENT: Placebo sachet|DIETARY_SUPPLEMENT: TCI904 sachet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Fondaparinux in Preventing Blood Clots in Patients Undergoing Surgery for Gynecologic Cancer
Status: COMPLETED
Conditions: Cervical Cancer|Endometrial Cancer|Fallopian Tube Cancer|Ovarian Cancer|Sarcoma|Thromboembolism|Vaginal Cancer|Vulvar Cancer
Interventions: DRUG: fondaparinux sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non-ablative Er:YAG for Recurrent Candidiasis
Status: COMPLETED
Conditions: Candidiasis, Vulvovaginal|Candidiasis of Vagina|Candidiasis, Genital|Recurrent Candidiasis of Vagina|Infection, Candida|Vaginal Yeast Infections
Interventions: DEVICE: Non-ablative SMOOTH mode Er:YAG laser
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility Of An Advanced Care Decision Aid Among Patients And Physicians_Matlock
Status: COMPLETED
Conditions: Palliative Care|Decision Making|Decision Support Techniques|Decision Support Systems, Clinical|Hospices
Interventions: BEHAVIORAL: End-of-Life / Advanced Care Decision Aid|BEHAVIORAL: Active Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety, Tolerability and Pharmacokinetic Study of MB12066 in Healthy Volunteers
Status: COMPLETED
Conditions: Metabolic Syndrome|Obesity
Interventions: DRUG: MB12066
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Bacteriophage Therapy for Difficult-to-treat Infections: the Implementation of a Multidisciplinary Phage Task Force
Status: RECRUITING
Conditions: Musculoskeletal Infection|Chronic Rhinosinusitis (Diagnosis)|Sepsis|Pulmonary Infection|Hidradenitis Suppurativa
Interventions: OTHER: Prospective data collection|OTHER: Prospective data collection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Amoxicillin Drug Interaction Study With MMX® Mesalazine/Mesalamine
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Amoxicillin + MMX placebo|DRUG: Amoxicillin + MMX mesalazine/mesalamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vibration-Assisted Anaesthesia
Status: COMPLETED
Conditions: Dermatochalasis|Blepharoptosis
Interventions: PROCEDURE: Vibration-assisted anaesthesia|PROCEDURE: Switched-off vibrating device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intervention for Multivitamin Adherence on Bariatric Patients
Status: UNKNOWN
Conditions: Adherence, Medication
Interventions: BEHAVIORAL: Cognitive Dissonance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: N-Acetylcysteine in Heart Failure With Coexistent Chronic Renal Failure
Status: UNKNOWN
Conditions: Heart Failure, Congestive|Kidney Failure, Chronic
Interventions: DRUG: N-acetylcysteine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Brilacidin to Treat Serious Skin Infections
Status: COMPLETED
Conditions: Skin Infection|Bacterial Infection
Interventions: DRUG: Daptomycin|DRUG: Brilacidin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Pharmacokinetic Study of Single Doses of Sativex in Treatment-induced Mucositis
Status: TERMINATED
Conditions: Head and Neck Squamous Cell Carcinoma
Interventions: DRUG: Sativex
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: OT-551 Antioxidant Eye Drops to Treat Geographic Atrophy in Age-Related Macular Degeneration
Status: COMPLETED
Conditions: Geographic Atrophy|Age-Related Macular Degeneration|AMD
Interventions: DRUG: OT-551 antioxidant eye drop
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Effect of AK3280 on Renal Function in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: AK3280|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficiency of Radiofrequency Ablation for Surgical Treatment of Chronic Atrial Fibrillation With Rheumatic Valve Disease
Status: UNKNOWN
Conditions: Rheumatic Valve Disease|Atrial Fibrillation
Interventions: PROCEDURE: Cardioblate® Surgical Ablation System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioavailability of LY03004 and Risperdal® Consta®
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder
Interventions: DRUG: LY03004|DRUG: Risperdal® Consta®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gadoxetate Sodium Enhanced MRI as a Biomarker for Aggressive Prostate Cancer
Status: UNKNOWN
Conditions: Cancer of the Prostate|Castration-resistant Prostate Cancer
Interventions: DRUG: Gadoxetate Sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Acetazolamide and Furosemide on Obesity-induced Glomerular Hyperfiltration
Status: COMPLETED
Conditions: Obesity-induced Hyperfiltration
Interventions: DRUG: Furosemide first, then Acetazolamide|DRUG: Acetazolamide first, then Furosemide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of IMM-101 in Combination With Checkpoint Inhibitor Therapy in Advanced Melanoma
Status: COMPLETED
Conditions: Melanoma
Interventions: DRUG: Nivolumab|DRUG: Ipilimumab|DRUG: IMM-101
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acupuncture and Integrative Care in Gynecological Surgery
Status: RECRUITING
Conditions: Quality of Life
Interventions: OTHER: Acupuncture and touch/relaxation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study to Evaluate the Safety and Efficacy of Ciprofloxacin (Inhaled) in Patients With Cystic Fibrosis
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: Ciprofloxacin (Cipro Inhale, BAYQ3939)|DRUG: Placebo|DRUG: Ciprofloxacin (Cipro Inhale, BAYQ3939)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Effects of Probiotics in Children Grades 1-3
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: Placebo|OTHER: Lactobacillus (Probiotic 1)|OTHER: Lactobacillus and Bifidobacterium (Probiotic 2)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Accuracy of Pulse Pressure Variations Measured by a Non Invasive Digital Device to Predict Fluid Responsiveness
Status: TERMINATED
Conditions: Systemic Inflammatory Response Syndrome|Circulatory Failure|Mechanical Ventilation
Interventions: OTHER: Pulse pressure variations
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study Of Crizotinib Plus VEGF Inhibitor Combinations In Patients With Advanced Solid Tumors.
Status: WITHDRAWN
Conditions: Carcinoma, Renal Cell|Glioblastoma|Carcinoma, Hepatocellular
Interventions: DRUG: Crizotinib plus VEGF inhibitor combinations|DRUG: Crizotinib plus axitinib|DRUG: Crizotinib plus sunitinib|DRUG: Crizotinib plus axitinib|DRUG: Crizotinib plus sunitinib|DRUG: Crizotinib plus bevacizumab|DRUG: Crizotinib plus sorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intravenous Imatinib in Mechanically Ventilated COVID-19 Patients
Status: TERMINATED
Conditions: ARDS|Acute Respiratory Distress Syndrome|Covid19|Endothelial Dysfunction|Pulmonary Edema
Interventions: DRUG: Imatinib Mesylate intravenous solution|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Everolimus 5 mg vs 10 mg/Daily for Patients With Neuroendocrine Tumors
Status: RECRUITING
Conditions: Neuroendocrine Tumors|Progression|Neuroendocrine Tumor Grade 1|Neuroendocrine Tumor Grade 2|Neuroendocrine Tumor of Pancreas|Neuroendocrine Tumor of the Lung|Neuroendocrine Tumor Carcinoid
Interventions: DRUG: Everolimus 5 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Febuxostat on Adipokines and Kidney Disease in Diabetic Chronic Kidney Disease
Status: COMPLETED
Conditions: Chronic Kidney Disease|Diabetes
Interventions: DRUG: Febuxostat|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy and Peripheral Stem Cell Transplantation in Treating Patients With Neuroblastoma
Status: COMPLETED
Conditions: Neuroblastoma
Interventions: BIOLOGICAL: filgrastim|DRUG: carboplatin|DRUG: cisplatin|DRUG: cyclophosphamide|DRUG: doxorubicin hydrochloride|DRUG: etoposide|DRUG: isotretinoin|DRUG: melphalan|DRUG: topotecan hydrochloride|DRUG: vincristine sulfate|PROCEDURE: autologous bone marrow transplantation|PROCEDURE: bone marrow ablation with stem cell support|PROCEDURE: conventional surgery|PROCEDURE: peripheral blood stem cell transplantation|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sacubitril/Valsartan Versus Valsartan for Hypertensive Patients With Acute Myocardial Infarction
Status: UNKNOWN
Conditions: Myocardial Infarction|Hypertension
Interventions: DRUG: Sacubitril/Valsartan 49/51mg/Tab|DRUG: Valsartan 80mg/Tab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Safety and Efficacy of Thrombectomy System in the Intravascular Treatment of Acute Ischemic Stroke
Status: RECRUITING
Conditions: Acute Ischemic Stroke
Interventions: DEVICE: Mechanical thrombectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of GLYC-101 to Evaluate Outcomes After Laser Ablation
Status: COMPLETED
Conditions: Wounds
Interventions: DRUG: GLYC-101 Gel (0.1%)|DRUG: GLYC-101 Gel (1.0%)|DRUG: GLYC-101 Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Efficacy and Safety Study of Grazoprevir (MK-5172) + Elbasvir (MK-8742) in the Treatment of Chronic Hepatitis C Virus (HCV) Genotype (GT)1, 4, or 6 Infection in Treatment-Naïve Participants Who Are on Opiate Substitution Therapy (MK-5172-062)
Status: COMPLETED
Conditions: Chronic Hepatitis C
Interventions: DRUG: Grazoprevir 100 mg/Elbasvir 50 mg FDC tablet (MK-5172A)|DRUG: Placebo to Grazoprevir 100 mg/Elbasvir 50 mg FDC tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Long Term Outcomes of Rehabilitation and Drug Treatment for in Urgency Urinary Incontinence
Status: COMPLETED
Conditions: Urge Urinary Incontinence
Interventions: PROCEDURE: tolterodine|PROCEDURE: bladder training|PROCEDURE: pelvic floor muscle training|PROCEDURE: pelvic floor rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Safty and Efficacy Study of Infusion of iNKT Cells and CD8+T Cells in Patients With Advanced Solid Tumor
Status: UNKNOWN
Conditions: Non-small Cell Lung Cancer|Small Cell Lung Cancer|Pancreas Cancer|Hepatocellular Carcinoma|Gastric Cancer|Renal Cell Carcinoma
Interventions: BIOLOGICAL: Infusion of iNKT cells and CD8+T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: COVID-19 Study to Evaluate Safety, Tolerability, and Efficacy of REGN14256+Imdevimab for the Treatment of COVID-19 Adult and Adolescent Patients Without Risk Factors for Progression to Severe Disease
Status: TERMINATED
Conditions: SARS-CoV-2
Interventions: DRUG: REGN14256|DRUG: imdevimab|DRUG: casirivimab + imdevimab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Connect TF - An Investigation of Function and Usability of a New Adaptable Socket System
Status: UNKNOWN
Conditions: Prosthesis User|Amputation
Interventions: DEVICE: CONNECT TF adaptable socket system|DEVICE: Any conventional handmade socket
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Cognitive Performance in 4 Dairy Beverages
Status: COMPLETED
Conditions: Cognitive Performance
Interventions: OTHER: Chocolate milk shakes - Product 1|OTHER: Chocolate milk shakes - Product 2|OTHER: Chocolate milk shakes - Product 3|OTHER: Chocolate milk shakes - Product 4
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Interaction Study of Clopidogrel 300/75 mg Given Alone or With Omeprazole 80 mg 12 Hours Apart in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: clopidogrel|DRUG: Placebo|DRUG: omeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study Of Two Non-Myeloablative Stem Cell Transplant Strategies For Low-Grade Lymphoma And CLL
Status: TERMINATED
Conditions: Leukemia|Lymphoma
Interventions: BIOLOGICAL: therapeutic allogeneic lymphocytes|DRUG: cyclophosphamide|DRUG: cyclosporine|DRUG: fludarabine phosphate|DRUG: methotrexate|DRUG: mycophenolate mofetil|DRUG: tacrolimus|PROCEDURE: peripheral blood stem cell transplantation|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: AZD2014 and Fulvestrant in Patients With ER+ Advanced Metastatic Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Metastatic Breast Cancer
Interventions: DRUG: AZD2014|DRUG: Fulvestrant
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Branch Retinal Vein Occlusion (BRVO) Treatment With Bevacizumab and Dexamethasone or Bevacizumab Only.
Status: UNKNOWN
Conditions: Branch Retinal Vein Occlusion
Interventions: DRUG: Bevacizumab Ophthalmic and Intravitreal Dexamethasone|DRUG: Bevacizumab Ophthalmic
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigation of AcrySof® IQ PanOptix™ Presbyopia-Correcting Intraocular Lens (IOL) Model TFNT00
Status: COMPLETED
Conditions: Cataract
Interventions: DEVICE: AcrySof® IQ PanOptix™ Presbyopia-Correcting IOL
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevalence of Inflammatory Bowel Disease in Patients With Perianal Disease
Status: COMPLETED
Conditions: Inflammatory Bowel Disease|Perianal Fistula|Perianal Abscess
Interventions: DEVICE: capsule endoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Pilot Study of a Lifestyle Intervention on the Metabolic Syndrome (3ELM Study)
Status: COMPLETED
Conditions: Metabolic Syndrome
Interventions: BEHAVIORAL: ELM Group|OTHER: ELM Classes|OTHER: ELM Individual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ph I/II Study of Allogeneic SCT for Clinically Aggressive Sickle Cell Disease (SCD)
Status: ACTIVE_NOT_RECRUITING
Conditions: Sickle Cell Disease
Interventions: PROCEDURE: Allogeneic Non-Myeloablative Stem Cell Transplantation|DRUG: Alemtuzumab|DRUG: Sirolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Alkalinizing Agents Efficacy on Stone Risk in Patients on a Metabolically Controlled Diet
Status: NOT_YET_RECRUITING
Conditions: Kidney Stone
Interventions: DRUG: Potassium citrate|DRUG: Sodium bicarbonate|DIETARY_SUPPLEMENT: Litholyte|DIETARY_SUPPLEMENT: Crystal Lite|DRUG: Potassium Bicarbonate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Learn About the Safety of BIIB080 Injections and Whether They Can Improve Symptoms of Participants With Mild Cognitive Impairment Due to Alzheimer's Disease (AD) or Mild AD Dementia Between 50 to 80 Years of Age
Status: ACTIVE_NOT_RECRUITING
Conditions: Mild Cognitive Impairment Due to Alzheimer's Disease|Alzheimer's Disease Dementia
Interventions: DRUG: BIIB080|DRUG: BIIB080-matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Idelalisib in Combination With Bendamustine and Rituximab in Adults With Previously Untreated Chronic Lymphocytic Leukemia
Status: TERMINATED
Conditions: Chronic Lymphocytic Leukemia
Interventions: DRUG: Idelalisib|DRUG: Bendamustine|DRUG: Rituximab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Amikacin Lung Delivery With Two Nebulizers
Status: UNKNOWN
Conditions: Healthy|Cystic Fibrosis
Interventions: DEVICE: Nebulizer 1|DEVICE: Nebulizer 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Wear Measurements of E-Poly in an Uncemented THA With Either 32 or 36 mm Caput of Ceramics.
Status: UNKNOWN
Conditions: Primary Arthrosis|Osteoarthritis
Interventions: PROCEDURE: Total hip arthroplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Using Social Media to Decrease Healthcare Utilization for Pediatric Asthma
Status: ACTIVE_NOT_RECRUITING
Conditions: Asthma in Children
Interventions: OTHER: Social Media Enhanced Education|OTHER: Usual Asthma Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: An Observational Study of Avastin (Bevacizumab) in Combination With Carboplatin/Paclitaxel in First Line in Patients With Advanced Epithelial Ovarian, Fallopian Tube or Primary Peritoneal Cancer (OTILIA)
Status: COMPLETED
Conditions: Peritoneal Neoplasms
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Waitlist-Controlled Trial of the Unified Protocol for the Treatment of Emotional Disorders in Adolescents
Status: COMPLETED
Conditions: Anxiety Disorders|Depression
Interventions: BEHAVIORAL: Unified Protocol for Adolescents (UP-A)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Masitinib in the Treatment of Patients With Primary Progressive or Non-active Secondary Progressive Multiple Sclerosis
Status: RECRUITING
Conditions: Progressive Multiple Sclerosis
Interventions: DRUG: Placebo|DRUG: Masitinib (4.5)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Performance of the Penumbra Liberty Stent in the Treatment of Wide-Neck, Saccular, Intracranial Aneurysms
Status: WITHDRAWN
Conditions: Wide Neck Intracranial Aneurysms
Interventions: DEVICE: Liberty Stent
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testosterone and Lipolysis, Insulin Sensitivity and Protein Metabolism
Status: COMPLETED
Conditions: Hypogonadism
Interventions: DRUG: Testosterone (Testogel), GnRH analog (Leuprorelide) and Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Severe Cutaneous Adverse Reactions in Thailand
Status: UNKNOWN
Conditions: Steven-Johnson Syndrome|Toxic Epidermal Necrolysis|Drug Reaction With Eosinophilia and Systemic Symptoms|Acute Generalized Exanthematous Pustulosis|Generalized Bullous Fixed Drug Eruption
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Capmatinib and Spartalizumab Combination Therapy vs Docetaxel in Non-small Cell Lung Cancer
Status: COMPLETED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: Capmatinib|DRUG: Spartalizumab|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Oral BCX4161 as a Prophylactic Treatment for HAE
Status: COMPLETED
Conditions: Hereditary Angioedema
Interventions: DRUG: BCX4161|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Healthy Approach to Physical and Psychological Problems in Youngsters With IBD (HAPPY-IBD).
Status: COMPLETED
Conditions: Inflammatory Bowel Disease (IBD)|Ulcerative Colitis|Crohn's Disease|Anxiety|Depression
Interventions: BEHAVIORAL: Cognitive behavioral therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Clinical Performance of Daily Disposable Silicone Hydrogel Multifocal Toric Contact Lenses
Status: COMPLETED
Conditions: Visual Acuity
Interventions: DEVICE: JJVC Investigational Multifocal Toric Contact Lens manufactured in Senofilcon A (C3) material with UV blocker / HEV filter
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Vemurafenib/Cobimetinib With or Without Bevacizumab in Patients With Stage IV BRAFV600 Mutant Melanoma
Status: TERMINATED
Conditions: Melanoma|Metastatic Melanoma
Interventions: DRUG: Vemurafenib|DRUG: Bevacizumab|DRUG: Cobimetinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose Escalation to Dominant Intraprostatic Lesions (DIL) With MRI-TRUS Fusion High Dose Rate (HDR) Prostate Brachytherapy
Status: UNKNOWN
Conditions: Prostate Cancer
Interventions: RADIATION: MRI-TRUS fusion guided real time HDR
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness and Safety of Probiotic in Regulating Chronic Constipation
Status: COMPLETED
Conditions: Chronic Constipation
Interventions: DIETARY_SUPPLEMENT: Probiotic|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Beta Endorphins,Interleukin 1 and Interleukin 38 in Covid Patients Associated With Neuropsychological Manifestations.
Status: UNKNOWN
Conditions: Covid Patients
Interventions: DIAGNOSTIC_TEST: βeta endorphins, interleukin 6 and interleukin 38
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of the Effects of Pre-operative Deflazacort on Post-operative Pain, Edema and Trismus
Status: ACTIVE_NOT_RECRUITING
Conditions: Impacted Third Molar Tooth
Interventions: DRUG: Deflazacort 30 MG Oral Tablet|DRUG: Sugar pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Acetazolamide in Decompensated Heart Failure With Volume OveRload (ADVOR)
Status: COMPLETED
Conditions: Acute Decompensated Heart Failure|Volume Overload
Interventions: DRUG: Acetazolamide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cefixime for Alternative Syphilis Treatment
Status: COMPLETED
Conditions: Syphilis|Early Syphilis
Interventions: DRUG: Cefixime 400 milligram Oral Capsule [Suprax]|DRUG: Benzathine Penicillin G
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Associations Between Genetic Markers of Caffeine Metabolism, Appetite Hormones and Body Weight
Status: UNKNOWN
Conditions: Food Consumption and Appetite|Food Habits|Caffeine
Interventions: DIETARY_SUPPLEMENT: caffeine consumption
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Drug-drug Interaction Study Between Daclatasvir and Atazanavir/Ritonavir or Atazanavir/Cobicistat
Status: COMPLETED
Conditions: Hepatitis C|HIV
Interventions: DRUG: Daclatasvir|DRUG: Atazanavir|DRUG: Ritonavir|DRUG: Cobicistat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Evaluation of Urine Leakage of New Absorbing Incontinence Products in a Home Care Environment
Status: COMPLETED
Conditions: Urinary Incontinence
Interventions: DEVICE: SN2|DEVICE: SP3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Impact of Extent of Antral Resection on Outcomes of Sleeve Gastrectomy
Status: COMPLETED
Conditions: Obesity
Interventions: PROCEDURE: LSG started 2 cm from the pylorus|PROCEDURE: LSG started 6 cm from pylorus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy in Treating Patients With AIDS-Related Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: BIOLOGICAL: filgrastim|DRUG: cyclophosphamide|DRUG: cytarabine|DRUG: methotrexate|DRUG: pegylated liposomal doxorubicin hydrochloride|DRUG: prednisone|DRUG: vincristine sulfate|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Impact of Decision Aids to Enhance Shared Decision Making for Diabetes
Status: COMPLETED
Conditions: Diabetes
Interventions: OTHER: Diabetes Medication Choice Decision Aid|OTHER: Statin Choice Decision Aid|OTHER: Usual care for lipid therapy medication|OTHER: Usual care for antihyperglycemic medication
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study to Evaluate the Safety, Immunogenicity, and Efficacy of Nanocovax Vaccine Against COVID-19
Status: ACTIVE_NOT_RECRUITING
Conditions: SARS-CoV-2 Infection|COVID-19
Interventions: BIOLOGICAL: Nanocovax|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Food, Gender, and Age on the Pharmacokinetic Profile of SUVN-911 in Healthy Subjects
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: SUVN-911
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exparel Use in Bilateral TAP Blocks for Postoperative Pain Control
Status: COMPLETED
Conditions: Postoperative Pain|Surgery|Anesthesia, Local
Interventions: DRUG: Exparel 266 MG Per 20 ML Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Flushing in Social Anxiety Disorder on Cipralex
Status: COMPLETED
Conditions: Social Anxiety Disorder
Interventions: DRUG: Cipralex|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: ARALAST NP Alpha-1 Lung Density Chronic Obstructive Pulmonary Disease-Emphysema (COPD-E) Study
Status: WITHDRAWN
Conditions: Chronic Obstructive Pulmonary Disease|Alpha1-antitrypsin Deficiency
Interventions: BIOLOGICAL: ARALAST NP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Cost-Effectiveness of Cost-free Pharmacotherapy for Smoking Cessation for High-risk Smokers With Cerebrovascular Disease
Status: COMPLETED
Conditions: Cerebrovascular Disorders|Smoking Cessation
Interventions: DRUG: Cost-Free Pharmacotherapy Group|OTHER: Prescription Only Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Phase II Clinical Study of the Efficacy and Safety of Tislelizumab Combined With Fruquintinib and Chidamide in the Treatment of Unresectable or Advanced Microsatellite Stabilized (MSS/pMMR) Colorectal Cancer With Liver Metastases
Status: NOT_YET_RECRUITING
Conditions: Colo-rectal Cancer
Interventions: DRUG: Tislelizumab|DRUG: Fruquintinib|DRUG: Chidamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rotational Atherectomy Combined With Cutting Balloon to Optimize Stent Expansion in Calcified Lesions
Status: COMPLETED
Conditions: Coronary Artery Disease|Atherosclerosis
Interventions: PROCEDURE: rotational atherectomy|DEVICE: cutting balloon|DEVICE: plain old balloon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Developing e-Covery, an App-based Intervention to Support Individuals With Co-occurring Problem Alcohol and Opioid Use
Status: COMPLETED
Conditions: Alcohol Use Disorder|Opioid Use Disorder
Interventions: OTHER: e-Covery|OTHER: Comparator Condition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study to Test the Hypothesis of Non-inferior Efficacy and Safety of Ferrum Lek® (Iron (III) Hydroxide Polymaltosate), 100 mg Chewable Tablets (Lek d.d., Slovenia), as Compared With MALTOFER® (Vifor S.A., Switzerland), in Subjects With Mild and Moderate Iron Deficiency Anemia.
Status: COMPLETED
Conditions: Mild and Moderate Iron-deficiency Anaemia
Interventions: DRUG: Ferrum Lek® (iron (III) hydroxide polymaltosate), 100 mg chewable tablets (Lek d.d., Slovenia)|DRUG: MALTOFER® (iron (III) hydroxide polymaltosate), 100 mg chewable tablets (Vifor S.A., Switzerland)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Folic Acid, Calcium and Vitamin D in Preventing Colorectal Polyps and Colorectal Cancer
Status: UNKNOWN
Conditions: Colorectal Neoplasms
Interventions: DRUG: folic acid|DRUG: folic acid calcium vitamin D3|DRUG: calcium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Implementation and Interaction of Clinician And Patient-facing Tools Aiming to Intensify Neurohormonal Medicines for Heart Failure
Status: NOT_YET_RECRUITING
Conditions: Heart Failure With Reduced Ejection Fraction
Interventions: BEHAVIORAL: EPIC-HF Patient-facing Tool|BEHAVIORAL: PROMPT-HF Clinician-facing Alert
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Preliminary Study of Microwave Tumoral Ablation Performances for the Treatment of Pulmonary, Renal and Bone Neoplasia.
Status: COMPLETED
Conditions: Lung Tumor|Bone Tumor|Renal Tumor
Interventions: DEVICE: Microwave ablation with Acculis Accu2i pMTA Applicator
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Losartan and Inflammation in Cystic Fibrosis
Status: TERMINATED
Conditions: Cystic Fibrosis
Interventions: DRUG: Losartan|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics, Safety and Tolerability of the Preservative-free Fixed Dose Combination of Tafluprost 0.0015% and Timolol 0.5% Eye Drops
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Preservative free tafluprost 0.0015% eye drops|DRUG: Preservative free timolol 0.5% eye drops|DRUG: Preservative free FDC of tafluprost 0.0015% and timolol 0.5% eye drops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Safety of Irlanda-1-Association on the Treatment of Common Cold in Children
Status: WITHDRAWN
Conditions: Common Cold
Interventions: DRUG: Irlanda-1-Association|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: S.L. Spray Solution® and Difflam® and Acular®Spray for the Prevention of Postoperative Sore Throat
Status: COMPLETED
Conditions: Sore Throat
Interventions: DRUG: S.L.®|DRUG: Difflam Forte ®|DRUG: Acular®|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Chelation Therapy of Iron Overload With Pyridoxal Isonicotinoyl Hydrazone
Status: COMPLETED
Conditions: Anemia (Iron-Loading)|Beta-Thalassemia|Hematologic Diseases|Hemoglobinopathies|Thalassemia|Iron Overload
Interventions: DRUG: Chelation therapy|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of H1N1 Vaccines in Adults Aged 18 Years and Older
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: GSK2340274A|BIOLOGICAL: GSK2340273A|BIOLOGICAL: Saline placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Breathibg Exercises and Inhaler Trainingfor Chronic Obstructive Pulmonary Disease (COPD) Patients
Status: COMPLETED
Conditions: COPD|Breathlessness|Aerocele
Interventions: DEVICE: Inhaler training|BEHAVIORAL: Breathing exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: ADAPT: Addressing Depression and Pain Together
Status: COMPLETED
Conditions: Depression|Back Pain
Interventions: DRUG: Higher-dose venlafaxine|BEHAVIORAL: Supportive management|BEHAVIORAL: Problem Solving Therapy for Depression and Pain
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combined Use of BIOTRONIK Home Monitoring and Predefined Anticoagulation to Reduce Stroke Risk
Status: TERMINATED
Conditions: Atrial Fibrillation|Atrial Flutter|Stroke|Embolism, Systemic Arterial|Major Bleeding
Interventions: DRUG: Home Monitoring Guided OAC|DRUG: Physician-Directed OAC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Daphnetin Capsule In the Treatment of VaScular COgnitive Impairment Without Dementia
Status: NOT_YET_RECRUITING
Conditions: Cerebrovascular Disorders
Interventions: DRUG: Daphnetin Capsule|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Overnight Trials With Heat Stress in Autonomic Failure Patients With Supine Hypertension
Status: RECRUITING
Conditions: Hypertension|Pure Autonomic Failure|Multiple System Atrophy|Autonomic Failure
Interventions: OTHER: Heating pad|OTHER: Sham control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical and Microbial Efficacy of Besifloxacin Ophthalmic Suspension, 0.6% in the Treatment of Bacterial Conjunctivitis
Status: TERMINATED
Conditions: Bacterial Conjunctivitis
Interventions: DRUG: Besifloxacin|DRUG: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Pemetrexed Plus Oxaliplatin as First Line Therapy in Advanced Gastric Carcinoma
Status: COMPLETED
Conditions: Advanced Gastric Carcinoma
Interventions: DRUG: pemetrexed|DRUG: oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non-carious Cervical Lesions and Treatments
Status: COMPLETED
Conditions: Tooth Sensitivity
Interventions: DEVICE: Experimental: • Group LA|DEVICE: Placebo Comparator: • Group LA-P|OTHER: Experimental: • Group DE|OTHER: Placebo Comparator: • Group DE-P|OTHER: Experimental: • Group RGI|OTHER: Experimental: Group RX
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Skills-training for Reducing Risky Alcohol Use in App Form
Status: COMPLETED
Conditions: Alcohol Abuse|Alcohol Use Disorder|Alcohol Drinking|Alcohol Dependence|Alcohol; Harmful Use
Interventions: BEHAVIORAL: Telecoach|BEHAVIORAL: TeleCoach control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Trametinib in Treating Patients With Recurrent or Progressive Low-Grade Ovarian Cancer or Peritoneal Cavity Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Borderline Ovarian Serous Tumor|Micropapillary Serous Carcinoma|Ovarian Serous Adenocarcinoma|Primary Peritoneal Serous Adenocarcinoma|Recurrent Ovarian Low Grade Serous Adenocarcinoma|Recurrent Primary Peritoneal Serous Adenocarcinoma
Interventions: DRUG: Letrozole|DRUG: Paclitaxel|DRUG: Pegylated Liposomal Doxorubicin Hydrochloride|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration|DRUG: Tamoxifen Citrate|DRUG: Topotecan|DRUG: Trametinib Dimethyl Sulfoxide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Omega 3 in LES and APS
Status: UNKNOWN
Conditions: Systemic Lupus Erythematosus|Primary Antiphospholipid Syndrome
Interventions: DIETARY_SUPPLEMENT: EPA and DHA supplementation|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Genetic Analysis-Guided Dosing of FOLFIRABRAX in Treating Patients With Advanced Gastrointestinal Cancer
Status: COMPLETED
Conditions: Adenocarcinoma of Unknown Primary|Adult Cholangiocarcinoma|Gallbladder Carcinoma|Gastric Adenocarcinoma|Malignant Gastrointestinal Neoplasm|Metastatic Pancreatic Adenocarcinoma|Pancreatic Adenocarcinoma|Stage III Ampulla of Vater Cancer|Stage III Pancreatic Cancer|Stage IIIA Gallbladder Cancer|Stage IIIA Gastric Cancer|Stage IIIB Gallbladder Cancer|Stage IIIB Gastric Cancer|Stage IV Ampulla of Vater Cancer|Stage IV Gallbladder Cancer|Stage IV Gastric Cancer|Stage IV Pancreatic Cancer
Interventions: DRUG: Paclitaxel Albumin-Stabilized Nanoparticle Formulation|DRUG: Leucovorin Calcium|DRUG: Irinotecan Hydrochloride|DRUG: Fluorouracil|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treating Rhegmatogenous Retinal Detachment by Foldable Capsular Buckle
Status: UNKNOWN
Conditions: Rhegmatogenous Retinal Detachment|Surgery
Interventions: PROCEDURE: Foldable Capsular Buckle|PROCEDURE: Silicone scleral padding
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Sexual Health Education Given to Women in the Postmenopausal Period on Sexual Life
Status: UNKNOWN
Conditions: Sexuality|Menopause|Sexual Behavior
Interventions: OTHER: SEXUAL HEALTH EDUCATION
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION