pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: The Use of MicroRNAs Dysregulation as Potential Biomarkers for Effective Diagnosis of Endometriosis
Status: ACTIVE_NOT_RECRUITING
Conditions: Endometriosis
Interventions: PROCEDURE: 100 women undergoing surgery (laparoscopy / laparotomy) with presumed diagnosis of endometriosis|PROCEDURE: women with intraoperative and / or histopathology findings suggestive of endometriosis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: VentrAssistTM LVAD as a Bridge to Cardiac Transplantation - Pivotal Trial
Status: UNKNOWN
Conditions: End-stage Heart Failure|Cardiomyopathies
Interventions: DEVICE: VentrAssistTM Left Ventricular Assist Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 15 mg Mirtazapine Orally Disintegrating Tablets, Non-Fasting
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Mirtazapine 15 mg (Orally Disintegrating) Tablets|DRUG: REMERON SolTab® 15 mg Orally Disintegrating Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Optimizing Iron Suppletion After Roux-en-Y Gastric Bypass
Status: COMPLETED
Conditions: Iron Deficiency
Interventions: DRUG: Ferrous fumarate|DRUG: Ferrous gluconate|DRUG: Iron(III)carboxymaltose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Autologous Fecal Microbiota Transplantation to Prevent Antibiotic Resistant Bacteria Colonization
Status: COMPLETED
Conditions: Antibiotic Resistant Strain
Interventions: BIOLOGICAL: Autologous fecal microbiota transplant (Auto-FMP Enema)|OTHER: Placebo Enema Preparation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Reduction of MTX Levels After Glucarpidase Treatment in DLBCL Patients at Risk of CNS
Status: TERMINATED
Conditions: Diffuse Large B-Cell Lymphoma|Drug Toxicity
Interventions: DRUG: Glucarpidase 1000 UNT [Voraxaze]
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of CC-93538 in Adult and Adolescent Participants With Eosinophilic Esophagitis
Status: ACTIVE_NOT_RECRUITING
Conditions: Eosinophilic Esophagitis
Interventions: DRUG: CC-93538|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Examine the Effect of a Thermogenic Energy Drink in Healthy Adults
Status: COMPLETED
Conditions: Metabolism
Interventions: DIETARY_SUPPLEMENT: Thermogenic Energy Drink - Active Study Product Formula|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Different Gingival Biotypes on Dimensional Stability of Free Gingival Graft
Status: COMPLETED
Conditions: Gingival Recession|Atrophy
Interventions: PROCEDURE: free gingival graft
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multimodal Pain Study in Free Flap Patients
Status: COMPLETED
Conditions: Head and Neck Cancer|Analgesia
Interventions: DRUG: Tylenol|DRUG: Oxycodone|DRUG: Morphine|DRUG: Gabapentin|DRUG: toradol|DRUG: Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: The Ultracyt Study - is EU-TIRADS Useful in Selecting Nodules for Fine Needle Aspiration Cytology?
Status: RECRUITING
Conditions: Thyroid Cancer|Thyroid Nodule
Interventions: DIAGNOSTIC_TEST: Non-selective cytology
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of VAY736 as Single Agent and in Combination With Select Antineoplastic Agents in Patients With Non-Hodgkin Lymphoma
Status: RECRUITING
Conditions: Non-Hodgkin Lymphoma, Diffuse Large B Cell Lymphoma, Follicular Lymphoma, Mantle Cell Lymphoma, Marginal Zone Lymphoma
Interventions: DRUG: VAY736|DRUG: lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ph2 NK Cell Enriched DCIs w/wo RLR9 Agonist, DUK-CPG-001 From Donors Following Allogeneic SCT
Status: ACTIVE_NOT_RECRUITING
Conditions: Myeloid Malignancies|Lymphoid Malignancies
Interventions: BIOLOGICAL: NK Cell enriched-DLI only|BIOLOGICAL: NK-DLI + DUK-CPG-001
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Intensity-Modulated Radiation Therapy in Treating Patients Undergoing Surgery for Stage IB, Stage II, or Stage III Soft Tissue Sarcoma
Status: TERMINATED
Conditions: Sarcoma
Interventions: GENETIC: gene expression analysis|GENETIC: polymerase chain reaction|GENETIC: western blotting|PROCEDURE: neoadjuvant therapy|PROCEDURE: therapeutic conventional surgery|RADIATION: intensity-modulated radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Detection of Clinical-functional Changes Following Exercise Therapy and Neuroscience Education in Institutionalised and Community-dwelling Older Adults Diagnosed With Sarcopenia
Status: RECRUITING
Conditions: Resistance Training|Aged|Nursing Homes|Sarcopenia
Interventions: OTHER: Physical therapy exercise programme
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Optimizing Pediatric HIV-1 Treatment in Infants With Prophylactic Exposure to Nevirapine, Nairobi, Kenya
Status: TERMINATED
Conditions: HIV Infections
Interventions: DRUG: AZT/3TC/NVP (zidovudine/lamivudine/nevirapine)|DRUG: d4T/3TC/NVP (stavudine/lamivudine/nevirapine)|DRUG: AZT/3TC/ABC (zidovudine/lamivudine/abacavir)|DRUG: d4T/3TC/ABC (stavudine/lamivudine/abacavir)|DRUG: ddI/ABC/LPV/r (didanosine/abacavir/lopinavir-ritonavir)|DRUG: ABC/ ddI or TDF / NVP or EFV (abacavir / didanosine or tenofovir / nevirapine or efavirenz)|DRUG: ABC/3TC/NVP (abacavir/lamivudine/nevirapine)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Patients With Intermittent Claudication Injected With ALDH Bright Cells
Status: COMPLETED
Conditions: Peripheral Artery Disease|Intermittent Claudication
Interventions: BIOLOGICAL: ALD-301|BIOLOGICAL: Placebo (vehicle)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Human Bone Marrow Stem Cells for Treatment of HBV-related Liver Cirrhosis
Status: UNKNOWN
Conditions: Liver Cirrhosis|End Stage Liver Disease
Interventions: OTHER: BMSC transplantation|OTHER: conventional treatment & antivrial treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Flavopiridol, Cytarabine, and Mitoxantrone in Treating Patients With Relapsed or Refractory Acute Leukemia
Status: COMPLETED
Conditions: Adult Acute Megakaryoblastic Leukemia (M7)|Adult Acute Minimally Differentiated Myeloid Leukemia (M0)|Adult Acute Monoblastic Leukemia (M5a)|Adult Acute Monocytic Leukemia (M5b)|Adult Acute Myeloblastic Leukemia With Maturation (M2)|Adult Acute Myeloblastic Leukemia Without Maturation (M1)|Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities|Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)|Adult Acute Myeloid Leukemia With t(16;16)(p13;q22)|Adult Acute Myeloid Leukemia With t(8;21)(q22;q22)|Adult Acute Myelomonocytic Leukemia (M4)|Adult Erythroleukemia (M6a)|Adult Pure Erythroid Leukemia (M6b)|Malignant Neoplasm|Recurrent Adult Acute Lymphoblastic Leukemia|Recurrent Adult Acute Myeloid Leukemia
Interventions: DRUG: alvocidib|DRUG: cytarabine|DRUG: mitoxantrone hydrochloride|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study in Underrepresented Patient Population or Regimen Tolerability: SUPPoRT
Status: COMPLETED
Conditions: Human Immunodeficiency Virus Infections
Interventions: DRUG: Efavirenz 600mg|DRUG: Boosted Lexiva
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ketoconazole as Inhibitor of the Enzyme CYP17 in Locally Advanced or Disseminated Granulosa Cell Tumour of Ovary
Status: TERMINATED
Conditions: Granulosa Cell Tumour of the Ovary
Interventions: DRUG: Ketoconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Outcome of Meniscus Repair With or Without Platelet Rich Plasma
Status: WITHDRAWN
Conditions: Cartilage Disease
Interventions: PROCEDURE: Meniscus repair for red/white tears without PRP|PROCEDURE: Meniscus repair with PRP
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ketogenic Diet Interventions in Parkinson's Disease: Safeguarding the Gut Microbiome
Status: ACTIVE_NOT_RECRUITING
Conditions: Parkinson Disease
Interventions: BEHAVIORAL: Mediterranean-Ketogenic Diet|DIETARY_SUPPLEMENT: Mediterranean diet supplemented with medium-chain triglyceride oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Randomized Controlled Trial Assessing the Efficacy of a Communication Skills Training Program
Status: UNKNOWN
Conditions: Physician Patient Relationship
Interventions: BEHAVIORAL: Communication skills training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of Ocoxin-Viusid® in Advanced or Metastatic Ovarian Epithelial Cancer
Status: COMPLETED
Conditions: Carcinoma|Ovarian Neoplasm|Endocrine Gland Neoplasm|Urogenital Neoplasms|Ovarian Diseases|Adnexal Diseases|Genital Diseases, Female|Female Urogenital Diseases|Female Urogenital Diseases and Pregnancy Complications|Endocrine System Diseases|Gonadal Disorders|Genital Neoplasm, Female|Neoplasms, Glandular and Epithelial
Interventions: DIETARY_SUPPLEMENT: Ocoxin-Viusid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Pharmacokinetics and Effectiveness of Local LevoBupivacaine Injection on Primary Total Joint Replacement Model.
Status: COMPLETED
Conditions: Arthropathy
Interventions: DRUG: Levobupivacaine Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial Evaluating Efficacy and Safety of Prophylactic Administration of Concizumab in Patients With Severe Haemophilia A Without Inhibitors
Status: COMPLETED
Conditions: Haemostasis|Haemophilia A
Interventions: DRUG: Concizumab|DRUG: Turoctocog alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Virtual Mom Power With High-Adversity Mothers and Children (MPHAMC)
Status: COMPLETED
Conditions: Psychopathology
Interventions: BEHAVIORAL: Mom Power|BEHAVIORAL: Mom Power Informational Mailing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evidence for Health Improvement in People With Diabetes Using One Touch & Partner Solutions
Status: UNKNOWN
Conditions: Diabetes Mellitus, Type 2
Interventions: DEVICE: Cecelia Health plus OneTouch Verio Reflect® BGM and OneTouch Reveal® mobile app|DEVICE: Fitbit plus OneTouch Verio Reflect® BGM and OneTouch Reveal® mobile app|DEVICE: Noom plus OneTouch Verio Reflect® BGM and OneTouch Reveal® mobile app|DEVICE: Welldoc plus OneTouch Verio Reflect® BGM and Welldoc app
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combined Therapy Using Oxaliplatin and Gemcitabine Chemotherapy, Lenvatinib and PD1 Antibody (JS001) for Patients With Advanced and Unresectable Intrahepatic Cholangiocarcinoma
Status: UNKNOWN
Conditions: Cholangiocarcinoma, Intrahepatic
Interventions: DRUG: combined therapy using oxaliplatin and gemcitabine chemotherapy, Lenvatinib and PD1 antibody (JS001)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lipid-lowering Effect of a Plant Stanol Ester Supplement Product
Status: COMPLETED
Conditions: Hypercholesterolemia|Hyperlipidemias|Dyslipidemias
Interventions: DIETARY_SUPPLEMENT: Supplement product with plant stanol ester
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Drug-drug Interaction Study to Evaluate the Effect of Rifampicin and Febuxostat on the Pharmacokinetics of Methotrexate in Healthy Subjects
Status: COMPLETED
Conditions: Drug Interaction
Interventions: DRUG: Methotrexate Sodium|DRUG: Rifampicin Sodium|DRUG: Febuxostat Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics Study Of PF-04427429 In Healthy Women Volunteers
Status: COMPLETED
Conditions: Pain|Migraine Disorders
Interventions: BIOLOGICAL: PF-04427429|OTHER: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pivotal Study of OCS-01 Eye Drops in Subjects With Diabetic Macular Edema (DIAMOND-1)
Status: RECRUITING
Conditions: Diabetic Macular Edema
Interventions: DRUG: Dexamethasone ophthalmic suspension (OCS-01)|DRUG: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Investigation of the VytronUS Ablation System for Treatment of Paroxysmal Atrial Fibrillation
Status: COMPLETED
Conditions: Paroxysmal Atrial Fibrillation
Interventions: DEVICE: VytronUS Ablation System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EEG Microstates Across At-Risk Mental States
Status: RECRUITING
Conditions: Psychotic Disorders|Autism Spectrum Disorder|Major Depressive Disorder|Schizophrenia
Interventions: DEVICE: EEG 64 channels|DEVICE: Polysomnography 19 electrodes|BEHAVIORAL: Light hypnosis|BIOLOGICAL: Biological sampling|BEHAVIORAL: Virtual reality|DEVICE: Voice recording
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Ozurdex in Suboptimal Diabetic Macular Edema Patients
Status: UNKNOWN
Conditions: Diabetic Macular Edema
Interventions: DRUG: Intravitreal Implant in Applicator|DRUG: Eylea
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Gefapixant (AF-219/MK-7264) in Participants With Idiopathic Pulmonary Fibrosis (IPF) With Persistent Cough (MK-7264-016)
Status: COMPLETED
Conditions: Idiopathic Pulmonary Fibrosis|Cough
Interventions: DRUG: Gefapixant|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety, Tolerability, Drug Levels, Food, Formulation, and pH Effects on Relative Absorption of BMS-986465 and Its Active Derivative BMS-986464 in Healthy Participants
Status: RECRUITING
Conditions: Healthy Participants
Interventions: DRUG: BMS-986465|OTHER: Placebo|DRUG: Pegasys|DRUG: Famotidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of REcombinant Human Thrombopoietin (rhTPO) on Sepsis Patients With aCUte Severe thrombocytopEnia
Status: RECRUITING
Conditions: Sepsis|Thrombocytopenia
Interventions: DRUG: rhTPO|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Toripalimab With Neoadjuvant Chemotherapy for Locally Advanced Esophageal Squamous Cell Carcinoma
Status: UNKNOWN
Conditions: Esophageal Squamous Cell Carcinoma
Interventions: DRUG: Toripalimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Efficacy and Tolerance of Cladribine in Symptomatic Pulmonary Langerhans Cell Histiocytosis
Status: UNKNOWN
Conditions: Langerhans Cell Histiocytosis of Lung
Interventions: DRUG: Cladribine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exenatide in Extreme Pediatric Obesity
Status: COMPLETED
Conditions: Obesity
Interventions: DRUG: Exenatide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing The Outcome of Large-Diameter vs Small-Diameter Glenospheres in Primary Reverse Shoulder Arthroplasty
Status: COMPLETED
Conditions: Glenohumeral Joint Degeneration
Interventions: DEVICE: ReUnion System with a Large-Diameter Glenosphere +2 mm offset|DEVICE: ReUnion System with a Small-Diameter Glenosphere +2 mm offset|DEVICE: ReUnion System with a Large-Diameter Glenosphere +6 mm offset|DEVICE: ReUnion System with a Small-Diameter Glenosphere +6 mm offset
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Denosumab on the Pharmacokinetics of Etanercept
Status: TERMINATED
Conditions: Postmenopausal|Osteopenia|Rheumatoid Arthritis|Osteoporosis
Interventions: DRUG: Etanercept|DRUG: Denosumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mask Ventilation With Different Face Masks During Neonatal Resuscitation
Status: COMPLETED
Conditions: Respiration; Insufficient or Poor, Newborn
Interventions: PROCEDURE: Mask ventilation with a Laerdal face mask|PROCEDURE: Mask ventilation with a F&P face mask
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sorafenib and Bortezomib in Treating Patients With Advanced Cancer
Status: COMPLETED
Conditions: Refractory Chronic Lymphocytic Leukemia|Refractory Multiple Myeloma|Stage III Multiple Myeloma|Stage IV Chronic Lymphocytic Leukemia|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: 17-N-allylamino-17-demethoxygeldanamycin/bortezomib|DRUG: sorafenib tosylate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pain Control for Breast Cancer Patients Receiving Injection of Radioactive Tracer
Status: COMPLETED
Conditions: Breast Cancer|Sentinel Lymph Node|Breast Neoplasms|Breast Cancer Female
Interventions: DRUG: Lidocaine patch|DEVICE: Buzzy(R)|OTHER: Ice pack
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Septal - Success Rate and Clinical Outcome of Septal Implant of Ventricular Defibrillation Lead
Status: COMPLETED
Conditions: Ventricular Tachycardia|Ventricular Fibrillation
Interventions: DEVICE: Endotak Reliance G
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: A Study to Evaluate the Efficacy and Safety of Hemay005 in the Treatment of Behçet Disease
Status: TERMINATED
Conditions: Behçet Disease
Interventions: DRUG: Hemay005|DRUG: Hemay005|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Billroth II With Braun Anastomosis After Radical Distal Gastrectomy for Gastric Cancer
Status: NOT_YET_RECRUITING
Conditions: Gastric Cancer|Surgery|Anastomosis|Gastrostomy
Interventions: PROCEDURE: Billroth II reconstruction|PROCEDURE: Braun Anastomosis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Combinations of D-CIK Immunotherapy And Anti-PD-1 In Refractory Solid Tumors
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma|Renal Cell Carcinoma|Bladder Cancer|Colorectal Cancer|Non-small-cell Lung Cancer|Breast Cancer
Interventions: BIOLOGICAL: D-CIK and anti-PD-1 antibody
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HEALEY ALS Platform Trial - Regimen A Zilucoplan
Status: COMPLETED
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DRUG: Zilucoplan|DRUG: Matching Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Exploratory Study of Dipraglurant (ADX48621) for the Treatment of Patients With Blepharospasm
Status: UNKNOWN
Conditions: Blepharospasm|Dystonia
Interventions: DRUG: Dipraglurant|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Is Regional Oxygen Saturation Effective in Predicting Perfusion Parameters and Patient Outcomes in Liver Resection
Status: UNKNOWN
Conditions: Tissue Injury|Surgery|Absorption; Disorder
Interventions: DEVICE: StO2|DEVICE: O3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Analytical Treatment Interruption in a Patient With HIV Post Allogeneic Stem Cell Transplantation From a CCR5 delta32 Homozygous Donor
Status: NOT_YET_RECRUITING
Conditions: HIV-1-infection
Interventions: OTHER: discontinuation of ART
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Mannitol Versus Nitroglycerin for Kidney Injury Prevention in Robotic-assisted Radical Prostatectomy or Cystectomy
Status: RECRUITING
Conditions: Prostate Cancer|Bladder Cancer|Surgery|Renal Impairment|Renal Injury, Acute
Interventions: PROCEDURE: Nitroglycerin Infusion|PROCEDURE: Mannitol Infusion|PROCEDURE: Fluid Regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Dose-escalation Study of Lupartumab Amadotin (BAY1129980)
Status: TERMINATED
Conditions: Neoplasms
Interventions: DRUG: Lupartumab Amadotin (BAY1129980)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phyllantus Amarus for the Protection of Liver Health
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Phyllantus amarus|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Chinese Registry Study on Treatment of Cholecysto-Choledocholithiasis
Status: UNKNOWN
Conditions: Gallstones|Cholelithiasis|Cholecystolithiasis|Choledocholithiasis
Interventions: PROCEDURE: endoscopic sphincterotomy|PROCEDURE: laparoscopic common bile duct exploration|PROCEDURE: laparoscopic transcystic common bile duct exploration|PROCEDURE: laparoscopic cholecystectomy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: SMILE vs. LASIK Using Contoura With Phorcides
Status: NOT_YET_RECRUITING
Conditions: Myopia|Astigmatism
Interventions: DEVICE: WaveLight EX500 Excimer Laser System|DEVICE: VisuMax Surgical Laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility and Benefits of Reflexology in the Prevention of Neuropathy Induced by Oxaliplatin in Colorectal Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Colorectal Cancer
Interventions: OTHER: Foot reflexology
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phase IIa Study Evaluating AZD7798 in Crohn's Disease
Status: NOT_YET_RECRUITING
Conditions: Moderate to Severe Crohn's Disease
Interventions: DRUG: AZD7798|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Busulfan, Melphalan, Escalating Carfilzomib Conditioning Auto Stem Cell Transplantation for Multiple Myeloma (MM)
Status: UNKNOWN
Conditions: Multiple Myeloma
Interventions: DRUG: Carfilzomib|DRUG: Busulfan IV|DRUG: Melphalan IV
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Low-dose and High-dose Oxytocin Regimens for Labor Augmentation
Status: COMPLETED
Conditions: Dystocia
Interventions: DRUG: Oxytocin|OTHER: Sodium Chloride 0.9%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Arm 1: Lysate Pulsed Dendritic Cells (PV-001-DC) in Patients With Melanoma
Status: NOT_YET_RECRUITING
Conditions: Metastatic Melanoma
Interventions: BIOLOGICAL: PV-001-DC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Ad-RTS-hIL-12 + Veledimex in Pediatric Subjects With Brain Tumors Including DIPG
Status: TERMINATED
Conditions: Pediatric Brain Tumor|Diffuse Intrinsic Pontine Glioma
Interventions: BIOLOGICAL: Ad-RTS-hIL-12|DRUG: Oral Veledimex - Arm 1 (Pediatric Brain Tumor)|DRUG: Oral Veledimex - Arm 2 (DIPG)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Priming Before in Vitro Maturation for Fertility Preservation in Breast Cancer Patients
Status: UNKNOWN
Conditions: Fertility Preservation|Breast Cancer
Interventions: OTHER: No hormone|OTHER: hCG|OTHER: GnRH a
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Non-Invasive Targeted Electronic Pain Control Device ("Biowave System") Versus Transcutaneous Electrical Nerve Stimulation (TENS) for the Symptomatic Treatment of Chronic Low Back Pain
Status: COMPLETED
Conditions: Chronic Low Back Pain
Interventions: DEVICE: Biowave Targeted Non-Invasive Electronic Pain Control Device|DEVICE: TENS (Transcutaneous Electrical Nerve Stimulation) device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Linagliptin (5 mg Administered Orally Once Daily) Over 24 Weeks in Type 2 Diabetic Patients With Insufficient Glycaemic Control Despite Metformin Therapy
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Linagliptin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: The Role of ARTificial Uterine CONtractions in Perinatal Respiratory Morbidity of Term Infants Delivered by Elective Caesarean Section
Status: NOT_YET_RECRUITING
Conditions: Neonatal Respiratory Distress
Interventions: DRUG: Oxytocin|OTHER: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Improving Pancreas Radiotherapy Plans Using Respiration-driven Anatomic Deformation: A Pilot Study
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: OTHER: Magnetic Resonance Imaging (MRI)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Trial for Relapsed and Relapsed/Refractory Multiple Myeloma Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Myeloma|Deletion 17P Syndrome
Interventions: DRUG: Daratumumab|DRUG: Pomalidomide|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Implementation of Guidelines on Hereditary or Familial Colorectal Cancer
Status: UNKNOWN
Conditions: Colorectal Neoplasms, Hereditary Nonpolyposis
Interventions: OTHER: Implementation aids|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study in Healthy Participants to Assess the Effect of Darunavir, Emtricitabine, and Tenofovir Alafenamide in the Presence of Cobicistat as Fixed Dose Combination (Darunavir/Cobicistat/Emtricitabine/Tenofovir Alafenamide) Compared With Co-administration of the Separate Agents
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Darunavir/Cobicistat/Emtricitabine/Tenofovir Alafenamide FDC|DRUG: Darunavir|DRUG: Emtricitabine/Tenofovir Alafenamide|DRUG: Cobicistat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Gemcitabine/Vinorelbine Versus Gemcitabine/Cisplatin Versus Gemcitabine/Capecitabine in Metastatic Breast Cancer
Status: COMPLETED
Conditions: Metastatic Breast Cancer
Interventions: DRUG: gemcitabine|DRUG: cisplatin|DRUG: vinorelbine|DRUG: capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Acupressure and Father's Lap on Pain and Physiological Parameters During Heel Lancing
Status: RECRUITING
Conditions: Infant Development|Nurse's Role|Pain, Acute
Interventions: OTHER: Acupressure|OTHER: Father's Lap
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: H7N9 Vaccination With and Without AS03 and Unadjuvanted H3N2v Vaccination: Standard and Systems Biology Analyses
Status: COMPLETED
Conditions: Avian Influenza|H1N1 Influenza|Influenza
Interventions: DRUG: AS03|BIOLOGICAL: Influenza Virus Vaccine, Monovalent A/H3N2v A/Minnesota/11/2010 NYMC X-203|BIOLOGICAL: Monovalent influenza A/H7N9 virus vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Selective Antibiotics When Symptoms Develop Versus Universal Antibiotics for Preterm Neonates
Status: NOT_YET_RECRUITING
Conditions: Sepsis|PROM, Preterm (Pregnancy)|Early-Onset Neonatal Sepsis|Preterm Premature Rupture of Membrane|Preterm Birth
Interventions: DRUG: Antibiotics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ALK37-005: A Study of ALKS 37 (RDC-1036) in Adults With Opioid-induced Constipation (OIC)
Status: COMPLETED
Conditions: Opioid-induced Constipation
Interventions: DRUG: ALKS 37|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of ex Vivo Drug Combination Optimization Platform in Recurrent High Grade Astrocytic Glioma
Status: RECRUITING
Conditions: Glioma, Astrocytic
Interventions: DRUG: QPOP category 1|DRUG: QPOP category 2
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cesarean Section Study
Status: COMPLETED
Conditions: Diarrhea|Atopic Dermatitis
Interventions: DIETARY_SUPPLEMENT: Probiotic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Efficacy of Different Procedures of Colpocleisis: a Randomized Controlled Trial
Status: NOT_YET_RECRUITING
Conditions: Pelvic Organ Prolapse
Interventions: PROCEDURE: total colpocleisis|PROCEDURE: partial colpocleisis (LeFort)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Thoracic Epidural Analgesia in Multiple Traumatic Fracture Ribs
Status: UNKNOWN
Conditions: Thoracic Epidural Analgesia, Fracture Ribs
Interventions: DRUG: Bupivacaine|DRUG: Magnesium Sulfate|DRUG: Fentanyl|PROCEDURE: Thoracic epidural
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Outcomes of Second Generation Laser Balloon Ablation for Atrial Fibrillation
Status: UNKNOWN
Conditions: Atrial Fibrillation|Atrial Fibrillation Paroxysmal|Atrial Fibrillation, Persistent
Interventions: PROCEDURE: Catheter Ablation for AF
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Lipofilling Versus Conservative Treatment in Fingertips Injuries Sequelae
Status: RECRUITING
Conditions: Distal Amputation of the Fingers
Interventions: PROCEDURE: autologous transplant reinjection|OTHER: desensitization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Prospective Study of the Dry Eye Drink That Evaluates Hydration and Subject's Assessment on Eye Dryness
Status: NOT_YET_RECRUITING
Conditions: Dry Eye
Interventions: DIETARY_SUPPLEMENT: Dry Eye Drink
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Using Neuromodulation to Improve Parkinson's Disease
Status: WITHDRAWN
Conditions: Parkinson Disease
Interventions: DEVICE: Experimental 1|DEVICE: Experimental 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Prebiotic Fiber- Enriched (scFOS) Enteral Feeding on the Microbiome in Neurological Injury Trauma Patients (PreFEED Microbiome Trial)
Status: COMPLETED
Conditions: Enteral Nutrition|Brain Injuries, Traumatic|ICU Admission
Interventions: OTHER: Nutraflora scFOS|OTHER: Osmolite
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Refralon Versus Amiodarone for Cardioversion of Paroxysmal Fibrillation and Atrial Flutter
Status: UNKNOWN
Conditions: Atrial Fibrillation Paroxysmal
Interventions: DRUG: Pharmacological cardioversion with Amiodarone|DRUG: Pharmacological cardioversion with Refralon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Serratus Anterior Plane Block and Costotransverse Block for Analgesia Following Modified Radical Mastectomy Surgeries
Status: RECRUITING
Conditions: Regional Anesthesia Morbidity
Interventions: PROCEDURE: serratus anterior plane block|PROCEDURE: costotransverse block|PROCEDURE: patient controlled analgesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Embeda (Kadian NT, ALO-01) in Subjects With Chronic Moderate to Severe Nonmalignant Pain
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: ALO-01 (Morphine Sulfate Plus Naltrexone Hydrochloride ER)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Amniotic Membrane Therapy for Interstitial Cystitis/Painful Bladder Syndrome
Status: RECRUITING
Conditions: Interstitial Cystitis|Painful Bladder Syndrome|Painful Bladder Syndrome (PBS)
Interventions: DRUG: Clarix Flo|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Safety and Efficacy of Specific TIL-TCM Cells for Advanced Relapse-refractory or Metastatic Pancreatic Cancer
Status: UNKNOWN
Conditions: Advanced Pancreatic Cancer
Interventions: DRUG: Adoptive TIL-TCM transfer therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety Study Evaluating N6022 in Multiple-Ascending Doses in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: 5 mg/N6022|DRUG: Placebo|DRUG: 10mg/N6022|DRUG: 20mg/N6022
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Predicting Ipsilesional Motor Deficits in Stroke With Dynamic Dominance Model
Status: COMPLETED
Conditions: Stroke
Interventions: BEHAVIORAL: Less-Impaired Arm Training|BEHAVIORAL: Contralesional Arm Comparison
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: To Evaluate the Pharmacokinetic Drug Interactions, Safety and Drug Tolerance in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Treatment A|DRUG: Treatment B|DRUG: Treatment C|DRUG: Treatment D|DRUG: Treatment E
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Local Ablative Stereotactic Radiotherapy for Residual Hypermetabolic Lesion in Patients With Locally Advanced or Metastatic Non-small Cell Lung Cancer Long-term Responders to Immunotherapy
Status: RECRUITING
Conditions: Locally Advanced Non Small Cell Lung Cancer|Metastatic Non Small Cell Lung Cancer
Interventions: RADIATION: SRT|DRUG: Immunotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anti-CMV Cellular Immunity Quantification Using an IGRA Test in Kidney Transplant récipients and Hemodialysis Patients, Comparison to Control Patients
Status: COMPLETED
Conditions: Quantiferon-CMV|Cytomegalovirus Infections|Kidney Transplant Infection|Hemodialysis
Interventions: DIAGNOSTIC_TEST: Quantiferon CMV
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Influence of Dexmedetomidine Hypnosis on Cerebrospinal Fluid (CSF) Volume, Brain Diffusion and 'Stiffness' Characteristics.
Status: WITHDRAWN
Conditions: Cerebrospinal Fluid Pressure Increased
Interventions: DRUG: Dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Role of Histamine in Muscle Protein Synthesis Following Resistance Training
Status: RECRUITING
Conditions: Histamine
Interventions: DRUG: Placebo|DRUG: H1 blockade: Telfast: 180mg Fexofenadine|BEHAVIORAL: Resistance training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Intravenous Immunoglobulin for Acute Intracranial Hemorrhage
Status: UNKNOWN
Conditions: Intracranial Hemorrhage, Hypertensive
Interventions: DRUG: Immunoglobulin Therapy|OTHER: Standard management
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of SX-682 Alone and in Combination With Oral or Intravenous Decitabine in Subjects With Myelodysplastic Syndrome
Status: RECRUITING
Conditions: Myelodysplastic Syndromes
Interventions: DRUG: SX-682|DRUG: Decitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PET Brain and Whole Body Distribution Studies for Nociceptin/Orphanin FQ Peptide (NOP) Receptor Using [11C]NOP-1A
Status: COMPLETED
Conditions: Pain|Anxiety|Depression
Interventions: DRUG: NOP-1A
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Botulinum Toxin Effects on Plantar Ulcer Recurrence
Status: COMPLETED
Conditions: Diabetes Mellitus|Peripheral Neuropathy|Plantar Ulcers
Interventions: DRUG: Botulinum Toxin|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Oral BBR-012 in the Treatment of Diabetic Foot Ulcers, Proof of Concept Study
Status: UNKNOWN
Conditions: Diabetic Foot Ulcer
Interventions: DRUG: isoniazide|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Attention Deficit Hyperactivity Disorder (ADHD) in Adolescents With Substance Use Disorders (SUD)
Status: COMPLETED
Conditions: ADHD|Substance Abuse
Interventions: DRUG: Methylphenidate (OROS-MPH)|DRUG: Methylphenidate (OROS-MPH) - Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Curcumin Gel On Radiation Induced Oral Mucositis
Status: COMPLETED
Conditions: Radiation-Induced Mucositis|Head and Neck Cancer
Interventions: DRUG: Curcumin Gel|DRUG: Standard Preparation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effect of Different Body Positions and Channel Sheaths on RIRS
Status: RECRUITING
Conditions: Urolithiasis
Interventions: PROCEDURE: RIRS with f-UAS, lateral position|PROCEDURE: RIRS with f-UAS, lithotomy position|PROCEDURE: RIRS with traditional UAS, lithotomy position
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Pharmacokinetics of Camizestrant (AZD9833) When Administered Alone and in Combination With Itraconazole
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: Camizestrant|DRUG: Itraconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: IFC Therapy in Proximal Humerus Fractures
Status: COMPLETED
Conditions: Interferential Current in Proximal Humerus Fractures
Interventions: DEVICE: Interferential current|OTHER: Rehabilitation program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The PAC Study: Parents as Agents of Change in Pediatric Weight Management
Status: COMPLETED
Conditions: Obesity|Child
Interventions: BEHAVIORAL: Cognitive Behavioural Therapy (CBT)|BEHAVIORAL: Psycho-Education Program (PEP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fexofenadine Study On Filipino Children for The Relief of Perennial And Intermittent Allergic Rhinitis
Status: COMPLETED
Conditions: Rhinitis, Allergic, Perennial
Interventions: DRUG: Fexofenadine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Carnitine Consumption and Augmentation in Pulmonary Arterial Hypertension
Status: COMPLETED
Conditions: Pulmonary Arterial Hypertension|Familial Primary Pulmonary Hypertension|Primary Pulmonary Hypertension|Lung Diseases|Carnitine Nutritional Deficiency
Interventions: DIETARY_SUPPLEMENT: L-carnitine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: ASA404 or Placebo in Combination With Paclitaxel and Carboplatin as First-Line Treatment for Stage IIIb/IV Non-Small Cell Lung Cancer
Status: TERMINATED
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: ASA404|DRUG: Placebo|DRUG: carboplatin|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT