pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Comparison of Controlled Ventilation With the V60 Non-Invasive Ventilator vs. Traditional Mask Ventilation
Status: COMPLETED
Conditions: Respiratory Complications Due to Anesthesia
Interventions: DEVICE: Noninvasive Ventilator, V60 (Philips)|DEVICE: Manual Bag
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy Study of AuroLase Therapy in Subjects With Primary and/or Metastatic Lung Tumors
Status: TERMINATED
Conditions: Primary or Metastatic Lung Tumors
Interventions: DEVICE: AuroLase Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Micronutrients to Prevent Noise-induced Hearing Loss
Status: COMPLETED
Conditions: Noise-Induced Hearing Loss
Interventions: DRUG: beta-carotene, vitamins C and E, magnesium|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Enfortumab Vedotin and Stereotactic Radiation for Localized, Cisplatin Ineligible Muscle Invasive Bladder Cancer
Status: NOT_YET_RECRUITING
Conditions: Bladder Cancer
Interventions: DRUG: Enfortumab vedotin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of PF-06882961 in Japanese Adults With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Placebo|DRUG: PF-06882961
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Mechanism and Effects of Manipulating Chloride Homeostasis in Stable Heart Failure
Status: RECRUITING
Conditions: Decompensated Heart Failure
Interventions: DRUG: Lysine Chloride|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Capnographic Monitoring in Gastrointestinal Endoscopy for Elderly Patients
Status: COMPLETED
Conditions: Hypoxia|Gastric Cancer|Gastric Polyp|Colon Polyp|Colon Cancer|Esophageal Cancer
Interventions: DEVICE: Capnography monitoring|DEVICE: Standard monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Distraction Technique to Reduce Discomfort of Transnasal Fiberoptic Laryngoscopy
Status: COMPLETED
Conditions: Pain
Interventions: OTHER: Simple distraction technique|DRUG: Local Anesthetics,Topical
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy of Three-dimensionally Integrated Exercise for Scoliosis in Patients With Adolescent Idiopathic Scoliosis
Status: UNKNOWN
Conditions: Scoliosis,Idiopathic,Adolescent
Interventions: BEHAVIORAL: observation|BEHAVIORAL: three-dimensionally integrated exercise for scoliosis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Regional Anesthesia Following Pediatric Cardiac Surgery
Status: RECRUITING
Conditions: Atrial Septal Defect|Ventricular Septal Defect|Pain, Procedural
Interventions: PROCEDURE: Regional Anesthesia|PROCEDURE: Wound infiltration|DRUG: Ropivacaine 0.2% Injectable Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nurse-led Education on Patients With Chronic Heart Failure and Their Informal Caregivers
Status: NOT_YET_RECRUITING
Conditions: Heart Failure
Interventions: OTHER: Intervention 1 / Nurse-led patients' education|OTHER: Intervention 2 / Nurse-led patients' & caregivers' education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Efficacy of Capsule FMT in Treatment-naïve Patients With Newly Diagnosed Chronic Inflammatory Diseases
Status: RECRUITING
Conditions: Rheumatoid Arthritis|Ankylosing Spondylitis|Psoriatic Arthritis|Pulmonary Sarcoidosis|Crohn Disease|Ulcerative Colitis
Interventions: BIOLOGICAL: Faecal microbiota transplantation|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Drug-Drug Interactions of Brivaracetam and Ethanol in Healthy Male Subjects
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Brivaracetam|OTHER: Ethanol|OTHER: Brivaracetam Placebo|OTHER: Ethanol Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: IVR in Motor Rehabilitation
Status: RECRUITING
Conditions: Knee Injuries
Interventions: COMBINATION_PRODUCT: VR_Training_1PP|COMBINATION_PRODUCT: VR_Training_3PP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Study of SARS-CoV2 Virus (COVID-19) Seroprevalence in the Population of Creil Air Force Base (BA110)
Status: COMPLETED
Conditions: Sars-CoV2
Interventions: DIAGNOSTIC_TEST: Anti-SARS-CoV2 Serology|BEHAVIORAL: Questionnaire|DIAGNOSTIC_TEST: Anti-SARS-CoV2 serological controls and serum neutralization
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ADC3680B in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: ADC3680B|DRUG: ADC3680B|DRUG: ADC3680B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of a Pre Heparin Coated Dialysis Filter on Coagulation During Hemodialysis
Status: COMPLETED
Conditions: Renal Failure
Interventions: DEVICE: a pre-heparin-coated hemodialysis filter; Hepran
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: iPACK for Post-op Pain Following ACL Reconstruction
Status: COMPLETED
Conditions: ACL Injury|Post Operative Pain
Interventions: DRUG: Adductor Canal Block (ACB) Only|DRUG: Adductor Canal Block (ACB) + iPACK Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Motor Sparing Knee Block to Infiltration Analgesia for Pain Following Knee Arthroplasty
Status: UNKNOWN
Conditions: Osteoarthritis|Knee Arthroplasty|Pain Management
Interventions: PROCEDURE: Periarticular|PROCEDURE: Motor free|PROCEDURE: Motor free with dex|DRUG: Ropivacaine|DRUG: epinephrine|DRUG: morphine|DRUG: Ketorolac|DRUG: Dexmedetomidine|DRUG: saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Maximizing Patient Goal Attainment
Status: RECRUITING
Conditions: Knee Osteoarthritis|Knee Injuries|Knee Pain Chronic|Knee Injuries and Disorders
Interventions: BEHAVIORAL: Goal Attainment|BEHAVIORAL: Goal Development|BEHAVIORAL: Goal Tracking
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Patent Foramen Ovale Closure or Medical Therapy After Stroke - RESPECT Trial
Status: COMPLETED
Conditions: Cryptogenic Stroke
Interventions: DEVICE: AMPLATZER PFO Occluder|OTHER: Standard of Care - Medical Management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Quadrupled Semitendinosus Graft in Anterior Cruciate Ligament Reconstruction
Status: COMPLETED
Conditions: Anterior Cruciate Ligament Injury
Interventions: PROCEDURE: Quadrupled semitendinosus graft|PROCEDURE: ST-Gracilis graft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Efficacy of Epoetin Alfa Versus Placebo for the Treatment of Anemia in AIDS (Acquired Immunodeficiency Syndrome) Patients With Anemia Caused by the Disease and by Zidovudine (AZT) Therapy
Status: COMPLETED
Conditions: Acquired Immunodeficiency Syndrome|Anemia
Interventions: DRUG: epoetin alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: EUS-guided Intratumoral Gemcitabine in Locally Advanced Unresectable Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Adenocarcinoma
Interventions: DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radiation Therapy With or Without Chemotherapy in Treating Patients With Head and Neck Cancer That Has Been Removed During Surgery
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: DRUG: chemotherapy|DRUG: cisplatin|RADIATION: low-LET cobalt-60 gamma ray therapy|RADIATION: low-LET electron therapy|RADIATION: low-LET photon therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hepatic Arterial Infusion of Autologous Tumor Infiltrating Lymphocytes in Patients With Melanoma and Liver Metastases
Status: RECRUITING
Conditions: Metastatic Uveal Melanoma|Metastatic Cutaneous Melanoma
Interventions: DRUG: Autologous Tumor Infiltrating Lymphocytes|DRUG: Melphalan|DRUG: Interleukin-2
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pragmatic Randomized Controlled Trial of Non-pharmacological Treatment for Lumbar Disc Herniation : A Pilot Study
Status: COMPLETED
Conditions: Lumbar Disc Prolapse With Radiculopathy
Interventions: OTHER: KM non-pharmacological treatment group|OTHER: Pharmacological treatment group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of PHI 101 for the Treatment of AML
Status: UNKNOWN
Conditions: Relapsed or Refractory Acute Myeloid Leukemia
Interventions: DRUG: PHI-101
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Rhythmic Auditory Stimulation on Balance in Children With Cerebral Palsy.
Status: COMPLETED
Conditions: Cerebral Palsy
Interventions: OTHER: Rhythmic auditory stimulation (RAS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: On-Demand Oxygen Delivery System Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Oxygen Delivery|Patient Monitoring
Interventions: DEVICE: On Demand Oxygen Delivery|DEVICE: Traditional, Always-On, Oxygen Delivery|DEVICE: Oxygen Flow Stopped
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Gallium 68 Pentixafor in Patients With Neuroendocrine Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Neuroendocrine Tumors
Interventions: DRUG: [68Ga]Pentixafor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Pharmacokinetics of Intravenous Acyclovir in Oncologic Paediatric Patients
Status: RECRUITING
Conditions: Herpesviridae Infections|Herpes Simplex 1|Varicella Zoster Virus Infection|Transplantation Infection|Oncology
Interventions: OTHER: Pharmacokinetic analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Cosmetic Outcomes of Absorbable Versus Non-absorbable Sutures in Pediatric Facial Lacerations
Status: COMPLETED
Conditions: Lacerations|Wounds
Interventions: OTHER: Arm 2: Absorbable sutures|OTHER: Arm 1: non-absorbable sutures
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Long Term Cocoa Flavanol Intake on Blood Pressure and Platelet Function in Healthy Adults, Part 1
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Mars Cocoa Extract Capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Carboplatin, Everolimus, and Prednisone in Treating Patients With Metastatic Prostate Cancer That Progressed After Docetaxel
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: carboplatin|DRUG: RAD 001|DRUG: prednisone|OTHER: laboratory biomarker analysis|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics of Lidocaine in Healthy Adults
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Lidocaine 5% patch|DRUG: Lidocaine hydrochloride|DRUG: Lidoderm 5% patch
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Clinical Decision Support System and Patient Portal for Preventing Medication-related Falls in Older Patients
Status: RECRUITING
Conditions: Fall|Fall Injury|Fall Patients|Accidental Fall|Deprescriptions|Polypharmacy|Aged|Aged, 80 and Over
Interventions: DEVICE: CDSS|DEVICE: Patient Portal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate Safety and Effectiveness of G-POEM for Gastroparesis
Status: RECRUITING
Conditions: Gastroparesis
Interventions: PROCEDURE: Gastric peroral endoscopic myotomy.|PROCEDURE: Sham Gastric peroral endoscopic myotomy.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nitric Oxide Supplementation in Argininosuccinic Aciduria
Status: COMPLETED
Conditions: Argininosuccinic Aciduria|Argininosuccinate Lyase Deficiency|Urea Cycle Disorders
Interventions: DIETARY_SUPPLEMENT: Nitric oxide supplement|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: COIN-B: COntrolled Interruption of Nucleos(t)Ide Analogue Treatment in Chronic Hepatitis B Infections
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Hepatitis B
Interventions: OTHER: Cessation of ongoing treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Creatine Supplementation and Resistance Training in Premenopausal Females
Status: COMPLETED
Conditions: Health Behavior
Interventions: DIETARY_SUPPLEMENT: Creatine Monohydrate Supplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of Chinese Prescription Shugan Decoction on Irritable Bowel Syndrome（Diarrhea Type）
Status: COMPLETED
Conditions: Irritable Bowel Syndrome|Traditional Chinese Medicine
Interventions: DRUG: Shugan decoction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Graded Repetitive Arm Supplementary Program Versus Task Based Training on Upper Limb Function in Stroke Patients
Status: RECRUITING
Conditions: Stroke|Upper Extremity Paresis|Motor Activity
Interventions: OTHER: Graded repetitive arm supplementary program|OTHER: Task based training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Starter Formula on Infection Prevention
Status: COMPLETED
Conditions: Gastro-intestinal Infections|Infections With Fever
Interventions: OTHER: starter infant formula with pro and prebiotics|OTHER: Placebo comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety Study of Sr-hGH in Comparison With Daily hGH in ISS Patients
Status: COMPLETED
Conditions: Establishing Dose of Sr-hGH in ISS Patients
Interventions: DRUG: human growth hormone self-injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of LY3214996 Administered Alone or in Combination With Other Agents in Participants With Advanced/Metastatic Cancer
Status: COMPLETED
Conditions: Advanced Cancer|Metastatic Melanoma|Metastatic Non-small Cell Lung Cancer|Colorectal Cancer
Interventions: DRUG: LY3214996|DRUG: Midazolam|DRUG: Abemaciclib|DRUG: Nab-paclitaxel|DRUG: Gemcitabine|DRUG: Encorafenib|DRUG: Cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CIrculating Tumor DNA for Monitoring Response to First Line Chemotherapy in Unresectable PANcreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Cancer|Circulating Tumor DNA|KRAS Mutation-Related Tumors
Interventions: DIAGNOSTIC_TEST: Blood samples
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Partial Enteral Nutrition With a Unique Diet vs. Exclusive Enteral Nutrition for the Treatment of Pediatric Crohn's Disease
Status: COMPLETED
Conditions: Crohn's Disease
Interventions: OTHER: Unique Diet+Partial Enteral Nutrition|OTHER: Exclusive Enteral Nutrition (Modulen)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Omega-3-Acid Ethyl Esters 90 Soft Capsules for Lowering Very High Triglycerides
Status: UNKNOWN
Conditions: Hypertriglyceridemia
Interventions: DRUG: Omega-3-Acid Ethyl Esters 90 Soft Capsules|DRUG: Corn Oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Pharmacokinetics and Safety of Androxal in Male Subjects With Impaired Hepatic Function
Status: COMPLETED
Conditions: Secondary Hypogonadism
Interventions: DRUG: Androxal 25 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Stellate Ganglion Block With Lidocaine for the Treatment of COVID-19-Induced Parosmia
Status: RECRUITING
Conditions: Parosmia
Interventions: PROCEDURE: Stellate Ganglion Block|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cellulose Sulfate (CS) Gel and HIV in Nigeria
Status: TERMINATED
Conditions: HIV Infections|Gonorrhea|Chlamydia Infections
Interventions: DRUG: Cellulose Sulfate Vaginal Gel (Microbicide)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: An Extension Protocol for Virologically Suppressed Subjects Who Successfully Completed PRO140_CD03 Study
Status: UNKNOWN
Conditions: HIV-1-infection
Interventions: DRUG: PRO 140 350|DRUG: PRO 140 525|DRUG: PRO 140 700
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Strimvelis Registry Study to Follow-up Patients With Adenosine Deaminase Severe Combined Immunodeficiency (ADA-SCID)
Status: ENROLLING_BY_INVITATION
Conditions: Immunologic Deficiency Syndromes
Interventions: GENETIC: Strimvelis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical Trial on Binge Eating Disorder, Treatment With Naloxone Spray
Status: UNKNOWN
Conditions: Binge Eating Disorder
Interventions: DRUG: Naloxone|DRUG: naloxone placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Firefighter Thermoregulatory Responses in Active Fire With Betaine Supplementation
Status: ACTIVE_NOT_RECRUITING
Conditions: Body Temperature Changes|Body Water Dehydration|Inflammation
Interventions: DIETARY_SUPPLEMENT: Betaine|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Lidocaine in ERAS for FESS
Status: COMPLETED
Conditions: Intraoperative Bleeding
Interventions: DRUG: Lidocaine|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Investigating the Efficacy of a Dentifrice in Providing Long Term Relief From Dentinal Hypersensitivity
Status: COMPLETED
Conditions: Dentine Hypersensitivity
Interventions: DRUG: Stannous fluoride|DRUG: Sodium monofluorophosphate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Fascial Closure and Post-caesarean Pain
Status: UNKNOWN
Conditions: Pregnancy Related|Cesarean Section|Post-operative Pain|Fascial Closure|Surgical Technique
Interventions: PROCEDURE: Fascial closure method during caesarean section via pfannenstiel incision.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: The Desarda and Lichtenstein Techniques in Inguinal Hernia Treatment.
Status: TERMINATED
Conditions: Hernia, Inguinal
Interventions: PROCEDURE: Desarda technique|PROCEDURE: Lichtenstein technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Post-Authorization Safety Study of Interferon Beta Therapy in Participants With Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis, Relapsing-Remitting
Interventions: DRUG: SC Peginterferon beta-1a|DRUG: SC interferon beta-1a|DRUG: SC interferon beta-1b
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Influence of Red Grape Cells on Blood Pressure Vascular Function in People With Hypertension
Status: COMPLETED
Conditions: Hypertension
Interventions: DIETARY_SUPPLEMENT: RGC|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Detection of Integrin avb6 in IPF, PSC, and COVID19 Using PET/CT
Status: RECRUITING
Conditions: Idiopathic Pulmonary Fibrosis|Primary Sclerosing Cholangitis|Covid19 Pneumonia
Interventions: DRUG: [18F]FP-R01-MG-F2
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy and Safety of Lu AA34893 in Patients With Major Depressive Disorder
Status: TERMINATED
Conditions: Major Depressive Disorder
Interventions: DRUG: Lu AA34893|DRUG: Venlafaxine extended release|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Efficacy and Safety of Dexmedetomidine as an Adjuvant in Quadratus Lumborum Versus Epidural Block in Postoperative Patients
Status: NOT_YET_RECRUITING
Conditions: To Compare Efficacy of Dexmedetomidine in Bilateral Quadratus Lumborum vs Lumbar Epidural Blocks on Analgesia After Major Lower Abdominal Surgery
Interventions: OTHER: nerve block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Active Balance and Cardio Care Intervention on Physical and Cardiovascular Health in People With Chronic Stroke
Status: NOT_YET_RECRUITING
Conditions: Chronic Stroke
Interventions: BEHAVIORAL: Virtual reality based dance group|BEHAVIORAL: Active Comparator: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Relugolix and Enzalutamide in Combination With Radiation Therapy for the Treatment of Very High Risk Prostate Cancer, OPTIMAL Trial
Status: NOT_YET_RECRUITING
Conditions: Prostate Adenocarcinoma
Interventions: PROCEDURE: Biopsy|PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|DRUG: Enzalutamide|OTHER: Fluorine F 18 Piflufolastat|RADIATION: Image Guided Radiation Therapy|PROCEDURE: Magnetic Resonance Imaging|PROCEDURE: Positron Emission Tomography|OTHER: Questionnaire Administration|DRUG: Relugolix
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess Bioavailability & Food Effect of Different Liquid and Capsule Formulations of TMC435.
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: TMC435 150 mg capsule|DRUG: TMC435 150 mg oral suspension (20 mg/mL)|DRUG: TMC435 150 mg oral solution (10 mg/mL)|DRUG: TMC435 150 mg capsule concept K|DRUG: TMC435 150 mg capsule concept L
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Technology-assisted Upper Extremity Rehabilitation in Subjects With Incomplete Cervical Spinal Cord Injury
Status: ACTIVE_NOT_RECRUITING
Conditions: Spinal Cord Injuries
Interventions: OTHER: Technology-assisted upper extremity rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigation of the Effect of Superimposed Neuromuscular Electrical Stimulation in Patients With Knee Osteoarthritis.
Status: RECRUITING
Conditions: Knee Osteoarthritis
Interventions: OTHER: conventional physiotherapy|OTHER: NMES|OTHER: Superimposed NMES
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Angled-tip vs. Straight-tip Guidewire in Biliary Cannulation
Status: COMPLETED
Conditions: Bile Duct Diseases
Interventions: DEVICE: Angled guidewire|DEVICE: Straight guidewire
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Prevention of Perinatal Sepsis (PoPS): Evaluation of Chlorhexidine Wipes of Birth Canal and Newborn
Status: UNKNOWN
Conditions: Infant, Newborn, Diseases|Sepsis|Puerperal Infection
Interventions: DRUG: Chlorhexidine|PROCEDURE: Birth canal wipe|PROCEDURE: sterile water external genital wipe
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Preliminary Study of Dornase Alfa to Treat Chest Infections Post Lung Transplant.
Status: COMPLETED
Conditions: Lung Transplant Infection|Lower Respiratory Tract Infection
Interventions: DRUG: Dornase Alfa|DRUG: Isotonic Saline.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Quetiapine Extended Release (XR) for the Treatment of Menopausal Depression
Status: COMPLETED
Conditions: Major Depressive Disorder|Insomnia|Hot Flashes
Interventions: DRUG: Quetiapine Extended Release
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: International Sites: Novel Experimental COVID-19 Therapies Affecting Host Response
Status: TERMINATED
Conditions: COVID-19|SARS-CoV2 Infection|Coronavirus Infection
Interventions: DRUG: Fostamatinib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Osteoarthritis in Older Adults: Recovery of Mobility and Pain With a Topical Analgesic
Status: WITHDRAWN
Conditions: Knee Osteoarthritis
Interventions: DRUG: Biofreeze|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Protective Effect of Sivelestat Sodium on ARDS in Patients With Sepsis
Status: RECRUITING
Conditions: ARDS
Interventions: DRUG: Sivelestat sodium|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Sorafenib, Docetaxel, and Cisplatin in Treating Patients With Metastatic or Advanced Gastric or Gastroesophageal Junction Cancer
Status: COMPLETED
Conditions: Adenocarcinoma of the Gastroesophageal Junction|Metastatic Gastric Cancer|Advanced Unresectable Gastric Cancer
Interventions: DRUG: BAY 43-9006|DRUG: docetaxel|DRUG: cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Natriuretic Brain Pro-peptid Changes in Patients With Chronic Heart Failure Within a Cardiac Rehabilitation Program
Status: COMPLETED
Conditions: Chronic Heart Failure
Interventions: OTHER: controlled, supervised exercise protocol|OTHER: exercise protocol no supervised
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Off-the-Shelf Splints Versus Occupational Therapy Splints for Treatment of Trapeziometacarpal Arthrosis
Status: TERMINATED
Conditions: Trapeziometacarpal (TMC) Arthrosis
Interventions: DEVICE: Off-the-shelf splint|DEVICE: OT Splint
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Delirium After Cardiac Surgery in Intensive Care Units
Status: RECRUITING
Conditions: Intensive Care Unit Delirium|Cardiac Surgery|Post Operative Delirium
Interventions: OTHER: Personal Pictures|OTHER: Family Videos|OTHER: Family Videos - Intervention as required
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Physical Training Introduction in Lifestyle of Facioscapulohumeral Dystrophy Patients
Status: COMPLETED
Conditions: Muscular Dystrophy, Facioscapulohumeral
Interventions: OTHER: Physical training|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Testing Two Conditioning Regimen With a Single Prophylaxis of GVHD by Cyclophosphamide and Methotrexate Post-transplant in Patients Eligible for Matched-donor Allograft Transplantation
Status: RECRUITING
Conditions: Graft Versus Host Disease|Hematologic Malignancy
Interventions: DRUG: Methotrexate|DRUG: Post-Transplant Cyclophosphamide|DRUG: Fludarabine|DRUG: Cycophosphamide|DRUG: Anti-Thymoglobulin|RADIATION: total body irradiation|OTHER: hematopoietic stem cells|OTHER: Graft nuclear cells|OTHER: Donor Lymphocytes Injection|DRUG: Clofarabine|DRUG: Thiotepa|DRUG: Busulfan|DRUG: Fludarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PERiX: Comparison of Efficacy Between Placement of Epidural Catheters X-ray Guided and LOS Technique
Status: UNKNOWN
Conditions: Postoperative Pain|Postoperative Complications|Pancreatic Cancer|Haemodynamic Instability
Interventions: PROCEDURE: LOS|PROCEDURE: X-ray placement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Depression-Diabetes Mechanisms: Urban African Americans
Status: COMPLETED
Conditions: Diabetes|Depression
Interventions: BEHAVIORAL: Beating the Blues|DRUG: Escitalopram|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Topotecan in Combination With Docetaxel in Refractory and/or Advanced Solid Tumors
Status: COMPLETED
Conditions: Cancer
Interventions: DRUG: Topotecan|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CCRT With Temozolomide Versus RT Alone in Patients With IDH Wild-type/TERT Promoter Mutation Grade II/III Gliomas
Status: UNKNOWN
Conditions: Grade II/III Glioma
Interventions: DRUG: Temozolomide|RADIATION: Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Surgical Ablation Versus No Surgical Ablation for Patients With Atrial Fibrillation Undergoing Mitral Valve Surgery
Status: COMPLETED
Conditions: Atrial Fibrillation|Mitral Valve Insufficiency|Mitral Valve Stenosis
Interventions: PROCEDURE: MVS|DEVICE: Ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigation of the Pharmacokinetic Profile of CBD
Status: ACTIVE_NOT_RECRUITING
Conditions: Healthy
Interventions: DRUG: Cannabidiol|DRUG: Cannabidiol|DRUG: Cannabidiol|DRUG: Cannabidiol
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: KEYMAKER-U01 Substudy 01A: Efficacy and Safety Study of Pembrolizumab (MK-3475) With or Without Chemotherapy When Used With Investigational Agents in Treatment-naïve Participants With Stage IV Non-small Cell Lung Cancer (NSCLC) (MK-3475-01A/KEYMAKER-U01A)
Status: ACTIVE_NOT_RECRUITING
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: BIOLOGICAL: Pembrolizumab|DRUG: Carboplatin|DRUG: Paclitaxel|DRUG: Pemetrexed|BIOLOGICAL: Vibostolimab|BIOLOGICAL: Boserolimab|BIOLOGICAL: MK-4830|BIOLOGICAL: MK-0482|BIOLOGICAL: Ifinatamab Deruxtecan (I-DXd)|BIOLOGICAL: HER3-DXd
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Phototherapy in Individuals With Temporomandibular Disorder.
Status: UNKNOWN
Conditions: Temporomandibular Disorder.
Interventions: RADIATION: Phototherapy|RADIATION: Placebo phototherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hemostasis in COVID-19: an Adaptive Clinical Trial
Status: UNKNOWN
Conditions: COVID-19
Interventions: DRUG: acetylsalicylic acid|DRUG: Unfractionated heparin nebulized
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Context-Aware Mobile Intervention for Social Recovery in Serious Mental Illness
Status: ACTIVE_NOT_RECRUITING
Conditions: Schizophrenia|Schizoaffective Disorder|Mood Disorder, Psychotic
Interventions: BEHAVIORAL: mobile Social Interaction Therapy by Exposure (mSITE)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Instrument-assisted Soft Tissue Mobilization and Kinesiotape Application in Individuals With Chronic Neck Pain.
Status: COMPLETED
Conditions: Cervical Pain
Interventions: OTHER: Instrument Assisted Soft Tissue Mobilization|OTHER: Kinesiotape Application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of SRF617 With AB928 (Etrumadenant) and AB122 (Zimberelimab) in Patients With Metastatic Castration Resistant Prostate Cancer
Status: TERMINATED
Conditions: Metastatic Castration-resistant Prostate Cancer|Prostate Cancer
Interventions: DRUG: SRF617|DRUG: etrumadenant|DRUG: zimberelimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preliminary Efficacy of a Strength Training Intervention on Exercise Adherence and Weight Among Pre-Menopausal Women
Status: COMPLETED
Conditions: Physical Inactivity|Obesity
Interventions: BEHAVIORAL: Strength training-based exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy Study of Intracystic TARA-002 for the Treatment of Lymphatic Malformations in Participants 6 Months to Less Than 18 Years of Age
Status: RECRUITING
Conditions: Lymphatic Malformation
Interventions: BIOLOGICAL: TARA-002
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of Probiotic VSL#3 Administration on Metabolic and Immunological Profile of the Milk of Breastfeeding Mothers
Status: COMPLETED
Conditions: Allergy
Interventions: DIETARY_SUPPLEMENT: VSL#3 probiotic preparation|OTHER: Placebo VSL#3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Medication Management at Home Via Pharmacy Home Televisits
Status: RECRUITING
Conditions: Polypharmacy|Deprescribing|Telemedicine
Interventions: BEHAVIORAL: Medication management via televisit to home
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Fluorouracil, Semustine, and Vincristine Compared With BCG in Treating Patients With Dukes' B or Dukes' C Colon Cancer That Has Been Removed By Surgery
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: BIOLOGICAL: BCG vaccine|BIOLOGICAL: biological therapy|DRUG: fluorouracil|DRUG: semustine|DRUG: vincristine sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Effects of Robotic-assisted Gait Training In Non-Ambulatory Patients After Guillain-Barré Syndrome
Status: COMPLETED
Conditions: GBS
Interventions: DEVICE: Robot-assisted Gait Training|OTHER: conventional rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Apelin on the Lung Circulation in Pulmonary Hypertension
Status: UNKNOWN
Conditions: Pulmonary Arterial Hypertension|Heart Failure
Interventions: DRUG: Apelin|DRUG: Saline (Placebo)|DRUG: Saline (Placebo)|DRUG: Apelin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Predicting Placental Pathologies by Ultrasound Imaging
Status: COMPLETED
Conditions: Intrauterine Growth Restriction|Villitis|IUGR
Interventions: DIAGNOSTIC_TEST: Comprehensive Doppler Ultrasound of the Placenta|OTHER: Verasonics Ultrasound scanner (ultra-sensitive Doppler imaging)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Fasting Study of Escitalopram Oxalate Tablets 20 mg and Lexapro® Tablets 20 mg
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Escitalopram Oxalate Tablets 20 mg|DRUG: Lexapro® Tablets (20 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study of Shengxuening Tablet in the Treatment of Chemotherapy-related Anemia in Hematologic Tumors
Status: RECRUITING
Conditions: Hematological Malignancy|Cancer-Related Anemia
Interventions: DRUG: Shengxuening Tablet|DRUG: Ferrous succinate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radiotherapy and Anti-PD-1 in Low-risk ES-ENKTCL
Status: RECRUITING
Conditions: Early-stage|Extranodal NK-T-Cell Lymphoma, Nasal and Nasal-Type
Interventions: DRUG: Anti-PD-1 monoclonal antibody
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Renal Denervation by Allegro System in Patients With Resistant Hypertension
Status: TERMINATED
Conditions: Renal Denervation|Resistant Hypertension|Standard Medication
Interventions: DEVICE: renal denervation|OTHER: standard medication
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Photodynamic Treatment FOTOSAN® Efficacy in Periodontology
Status: COMPLETED
Conditions: Periodontitis
Interventions: OTHER: Fotosan®630. LED lamp. Toluidinblue. Photoactivated disinfection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety, Pharmacokinetics (PK), and Efficacy of Buprenorphine Transdermal System (BTDS) in Children
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Buprenorphine transdermal system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect and Safety of Marealis RPC (Refined Peptide Concentrate) in Mild or Moderate Hypertensive Subjects
Status: COMPLETED
Conditions: Prehypertension
Interventions: DIETARY_SUPPLEMENT: Marealis refined peptide concentrate|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Safety and Feasibility of EUS-guided RFA for Solid Pancreatic Neoplasms
Status: UNKNOWN
Conditions: Pancreatic Cancer|Pancreatic Neoplasms|Pancreatic Adenocarcinoma|Pancreatic Neuroendocrine Tumor|Pancreatic Ductal Adenocarcinoma
Interventions: DEVICE: EUSRA RFA needle
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cognitive Training RCT for Older Chinese Americans
Status: ENROLLING_BY_INVITATION
Conditions: Cognitive Health|mHealth Application|Experience-based Co-design|Cognitive Training|Ethnogeriatrics
Interventions: BEHAVIORAL: Cognitive Training Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Scottish and Newcastle Anti-emetic Pre-treatment for Paracetamol Poisoning Study (SNAP)
Status: COMPLETED
Conditions: Overdose
Interventions: DRUG: Ondansetron|DRUG: acetylcysteine|DRUG: acetylcysteine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bio-equivalence Vasoconstriction Activity Study for Topically Applied Clocortolone Pivalate 0.1% Cream
Status: COMPLETED
Conditions: Bioequivalence Study
Interventions: DRUG: Clocortolone Pivalate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Efficacy and Tolerability of Delamanid, Linezolid, Pyrazinamide and Levofloxacin
Status: WITHDRAWN
Conditions: Tuberculosis Multi Drug Resistant Active
Interventions: DRUG: Delamanid|DRUG: Linezolid|DRUG: Levofloxacin|DRUG: Pyrazinamide|DRUG: WHO MDR-TB regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The RELIEF™ Ureteral Stent - Assessment of Retrograde Urinary Reflux and Distal Coil Bladder Position
Status: COMPLETED
Conditions: Ureteral Obstruction
Interventions: DEVICE: RELIEF Stent
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The CorCinch - Functional Mitral Valve Regurgitation (FMR) Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Heart Failure|Mitral Valve Insufficiency|Cardiomyopathies
Interventions: DEVICE: Mitral valve repair
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: A Study to Observe and Evaluate the Safety and Efficacy of c610 Injection for Treatment of Advanced Solid Tumor Patients
Status: NOT_YET_RECRUITING
Conditions: Advanced Solid Tumors
Interventions: DRUG: c610 injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Decoding Mechanisms of Pain Modulation
Status: COMPLETED
Conditions: Pain, Acute
Interventions: BEHAVIORAL: Hypnosis|DEVICE: Vagus nerve stimulation|DEVICE: Sham control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT