pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Psilocybin for Major Depressive Disorder (MDD)
Status: RECRUITING
Conditions: Depressive Disorder, Major
Interventions: DRUG: Psilocybin 25 mg|DRUG: Inactive Placebo|DRUG: Psilocybin 5 mg|BEHAVIORAL: Psychosocial Support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Clinical Study of the Efficacy and Safety of L-Carnitine Injection in Treatment of Heart Failure
Status: COMPLETED
Conditions: Heart Failure,
Interventions: DRUG: Levocarnitine Injection|DRUG: Levocarnitine placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: GoalTracker: Comparing Self-Monitoring Strategies for Weight Loss
Status: COMPLETED
Conditions: Obesity|Overweight|Weight Loss
Interventions: BEHAVIORAL: self-monitoring of body weight|BEHAVIORAL: self-monitoring of diet|BEHAVIORAL: weekly personalized feedback + lessons + action plans
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Development of a Telehealth Obesity Intervention for Patients With MS: Modifying Diet and Exercise in MS
Status: COMPLETED
Conditions: Multiple Sclerosis|Obesity
Interventions: BEHAVIORAL: behavioral telehealth|OTHER: Treatment as Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Myofascial Release Technique on Sportive Performance, Balance and Injury Risk in Runners
Status: UNKNOWN
Conditions: Runt
Interventions: OTHER: Myofascial therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Plasma Concentrations of Intravenous Lidocaine and Epidural Ropivacaine When Used in Combination in Major Abdominal Surgery
Status: RECRUITING
Conditions: Abdominal Surgery by Laparotomy|Thoracic Epidural Analgesia|Analgesia|Lidocaine Adverse Reaction
Interventions: OTHER: Blood sample|DRUG: Lidocain|DRUG: ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Incidence of Chronic Pain After Thoracic Surgery
Status: RECRUITING
Conditions: Postoperative Pain|Postoperative Pain, Acute|Postoperative Pain, Chronic|Video-Assisted Thoracoscopic Surgery|Thoracotomy
Interventions: PROCEDURE: Thoracic surgery application
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: An Efficacy Study of IV Boosting With ChAd63/MVA ME-TRAP
Status: COMPLETED
Conditions: Malaria
Interventions: BIOLOGICAL: ChAd63 ME-TRAP and MVA ME-TRAP vaccination
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: GEN1046 Safety and PK in Subjects With Advanced Solid Malignancies
Status: ACTIVE_NOT_RECRUITING
Conditions: Solid Tumor
Interventions: BIOLOGICAL: Acasunlimab|BIOLOGICAL: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A 12-Week, Randomized, Double-Masked, Parallel Group Comparison Of Evening Dosing With Xalacom In Subjects With Glaucoma
Status: COMPLETED
Conditions: Glaucoma, Open-Angle|Ocular Hypertension
Interventions: DRUG: Xalacom|DRUG: Xalatan|DRUG: Timolol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety, Tolerability, PDs, and Efficacy of CNP-104 in Subjects With Primary Biliary Cholangitis
Status: ACTIVE_NOT_RECRUITING
Conditions: Primary Biliary Cholangitis
Interventions: DRUG: CNP-104|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Playtraining in ADHD Preschoolers on ADHD Symptoms and Play Persistence and Intensity
Status: UNKNOWN
Conditions: ADHD
Interventions: BEHAVIORAL: Experimental: playtraining|BEHAVIORAL: Placebo open play session
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: The Impact of Brief Motivational Counseling for Smoking Cessation in an Italian Emergency Department: a Randomized Controlled Trial
Status: COMPLETED
Conditions: Smoking Habit
Interventions: BEHAVIORAL: Brief counseling based on the 5As model
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Effects of Upper Airway Muscle Training on Obstructive Sleep Apnea Severity
Status: WITHDRAWN
Conditions: Sleep Apnea
Interventions: DEVICE: Exercise equipment (a musical instrument that is based on the Medical Didgeridoo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Exparel Injection for Postoperative Orbital Pain
Status: RECRUITING
Conditions: Pain, Postoperative
Interventions: DRUG: Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: AMG510 (Sotorasib) Plus Lenvatinib as Second-line Treatment in Patients With KRASG12C Mutant, Metastatic NSCLC
Status: WITHDRAWN
Conditions: Metastatic Non Small Cell Lung Cancer|KRAS G12C
Interventions: DRUG: Sotorasib|DRUG: Lenvatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Postoperative Pain in Laparoscopic Radical Prostatectomy Surgery With Tranexamic Acid: Analgesia? Hiperalgesia?
Status: NOT_YET_RECRUITING
Conditions: Pharmacological Action
Interventions: DRUG: Tranexamic acid intravenous administration|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: PMCF Study on the Safety, Performance and Clinical Benefits Data of the ToggleLoc™ 2.9mm and JuggerLoc™ in the Shoulder
Status: ENROLLING_BY_INVITATION
Conditions: Bankart Lesions|SLAP Lesion|Acromioclavicular; Dislocation|Capsular Shift/Capsulolabral Reconstruction|Deltoid Repair|Rotator Cuff Tear Repair|Biceps Tendon Disorder
Interventions: DEVICE: ToggleLoc 2.9 mm soft tissue device|DEVICE: JuggerLoc soft tissue device
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of Baricitinib (LY3009104) in Adult and Pediatric Japanese Participants With NNS/CANDLE, SAVI, and AGS
Status: ACTIVE_NOT_RECRUITING
Conditions: Nakajo-Nishimura Syndrome|Chronic Atypical Neutrophilic Dermatosis With Lipodystrophy and Elevated Temperature Syndrome|STING-Associated Vasculopathy With Onset in Infancy|Aicardi Goutieres Syndrome
Interventions: DRUG: Baricitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Augmenting Ankle Plantarflexor Function in Cerebral Palsy
Status: RECRUITING
Conditions: Cerebral Palsy
Interventions: DEVICE: Biomotum Spark: Robotic ankle assistance|DEVICE: Biomotum Spark: Robotic ankle resistance|OTHER: Standard gait training|DEVICE: Ankle foot orthosis|OTHER: Standard physical therapy|OTHER: Standard walking
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oxygenation Changes After 2-month Exercise in Sedentary Older Adults With Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Oxygen Deficiency
Interventions: BEHAVIORAL: 2-month home moderate-intensity exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Detection of Atrial Fibrillation by a Wearable Dynamic ECG Recorder
Status: UNKNOWN
Conditions: Atrial Fibrillation
Interventions: DEVICE: Wearable Dynamic ECG Recorder|DEVICE: 12-lead ECG recordings
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Hemiplegic Shoulder Pain and Rotator Cuff Injuries
Status: COMPLETED
Conditions: Shoulder Pain|Stroke|Rotator Cuff Injuries
Interventions: DRUG: Hyaluronic Acid|DRUG: Physiological saline solution|OTHER: physical therapy and occupational therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Colchicine to Treat Acute Pericarditis and Prevent Recurrences
Status: COMPLETED
Conditions: Pericarditis
Interventions: DRUG: Colchicine (for 3 months)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Post Market Study for VasQ, an External Support Implant for Arteriovenous Fistula
Status: NOT_YET_RECRUITING
Conditions: End Stage Renal Disease
Interventions: DEVICE: VasQ|PROCEDURE: Arteriovenous fistula creation for dialysis vascular access
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Investigation of Sleep in the Intensive Care Unit
Status: COMPLETED
Conditions: Delirium|Sleep
Interventions: DRUG: Dexmedetomidine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Research Study Looking at How the Medicine NNC0194-0499 Behaves in Japanese and Non-Asian Men
Status: COMPLETED
Conditions: Non-alcoholic Steatohepatitis
Interventions: DRUG: NNC0194-0499|DRUG: Placebo (NNC0194-0499 )
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Collecting and Storing Tissue Samples From Patients With Rare or Cutaneous Non-Hodgkin Lymphoma
Status: COMPLETED
Conditions: Adult Immunoblastic Lymphoma|Central Nervous System Non-Hodgkin Lymphoma|Childhood Immunoblastic Lymphoma|Grade 1 Follicular Lymphoma|Grade 2 Follicular Lymphoma|Grade 3 Follicular Lymphoma|Lymphoproliferative Disorder|Mantle Cell Lymphoma|Marginal Zone Lymphoma|Non-Hodgkin Lymphoma|Primary Cutaneous B-Cell Non-Hodgkin Lymphoma|Primary Cutaneous T-Cell Non-Hodgkin Lymphoma|Small Lymphocytic Lymphoma
Interventions: OTHER: Cytology Specimen Collection Procedure
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy of Melatonin, Low-dose Quetiapine, or Placebo in Patients With Psychiatric Disorders and Comorbid Insomnia
Status: RECRUITING
Conditions: Psychiatric Disorders|Insomnia
Interventions: DRUG: Melatonin|DRUG: Quetiapine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Cardiovascular Disease With Low Dose Rivaroxaban in Advanced Chronic Kidney Disease
Status: RECRUITING
Conditions: Chronic Kidney Diseases|Dialysis-dependent Kidney Failure|Cardiovascular Disease
Interventions: DRUG: Rivaroxaban 2.5 Mg Oral Tablet|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Pyridorin in Patients With Nephropathy Due to Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetic Nephropathy
Interventions: DRUG: Pyridoxamine Dihydrochloride|DRUG: Pyridoxamine Dihydrochloride|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Multicenter Phase II Study of Sentinel Node Detection in Squamous Cell Carcinoma T1-T2N0 of the Oropharynx Treated With Radiotherapy and Larynx Treated by Surgery, Laser or Robot
Status: UNKNOWN
Conditions: Head and Neck Cancer
Interventions: PROCEDURE: Detection and resection of sentinel lymph node
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Research on Outpatient Adolescent Treatment for Comorbid Substance Use and Internalizing Disorders
Status: COMPLETED
Conditions: Substance-Related Disorders|Depressive Disorder|Anxiety Disorder
Interventions: BEHAVIORAL: OutPatient Treatment for Adolescents (OPT-A)|BEHAVIORAL: Treatment As Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Diagnostic Accuracy of CEUS for HCC Diagnosis
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma
Interventions: DIAGNOSTIC_TEST: contrast-enhanced ultrasound|DIAGNOSTIC_TEST: EOB-MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Verapamil for Beta Cell Survival Therapy in Type 1 Diabetes
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus
Interventions: DRUG: Verapamil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Bumetanide for the Treatment of Autism Spectrum Disorders
Status: COMPLETED
Conditions: Autism Spectrum Disorder
Interventions: DRUG: Bumetanide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pain Associated With Endometriosis
Status: COMPLETED
Conditions: Endometriosis
Interventions: DRUG: Danazol Once Weekly|DRUG: Danazol Twice Weekly|DRUG: Placebo Once Weekly|DRUG: Placebo Twice Weekly
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hippotherapy in Children With Spinal Muscular Atrophy
Status: RECRUITING
Conditions: Spinal Muscular Atrophy
Interventions: PROCEDURE: Individual physiotherapy (SMA-SOC)|PROCEDURE: Hippotherapy|PROCEDURE: Therapeutic grooming
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Doxorubicin Hydrochloride or Trabectedin in Treating Patients With Previously Untreated Advanced or Metastatic Soft Tissue Sarcoma
Status: TERMINATED
Conditions: Sarcoma
Interventions: DRUG: doxorubicin hydrochloride|DRUG: trabectedin|OTHER: laboratory biomarker analysis|PROCEDURE: quality-of-life assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Newly Diagnosed Stage III/IV Ovarian Cancer, Neoadjuvant Carbo/Taxol/Pembro, Maintenance Olaparib/Pembro
Status: NOT_YET_RECRUITING
Conditions: Ovarian Cancer
Interventions: DRUG: Carboplatin|DRUG: olaparibp, embro
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Heterologous 3rd COVID-19 Vaccine of MVC-COV1901 to Evaluate Immunogenicity and Safety in Adults With ChAdOx1-nCov-19
Status: UNKNOWN
Conditions: COVID-19 Vaccine
Interventions: BIOLOGICAL: MVC-COV1901(3 Months)|BIOLOGICAL: MVC-COV1901(6 Months)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of Pneumostem® for IVH in Premature Infants (Phase 2a)
Status: UNKNOWN
Conditions: Cell Transplantation
Interventions: DRUG: Pneumostem|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Crystalloids and Colloids on Visceral Blood Flow
Status: COMPLETED
Conditions: Fluid Overload|Water Electrolyte Imbalance|Acid Base Imbalance
Interventions: DRUG: Crystalloid|DRUG: Colloid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized, Controlled Trial of Inspiratory Muscle Training (IMT)in the ICU and CCU
Status: COMPLETED
Conditions: Critically Ill|Respiratory Failure
Interventions: DEVICE: Inspiratory Muscle Trainer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: A Study Of PF-06410293 (Adalimumab-Pfizer) And Adalimumab (Humira®) In Combination With Methotrexate In Subjects With Active Rheumatoid Arthritis (REFLECTIONS B538-02).
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: BIOLOGICAL: PF-06410293|BIOLOGICAL: Adalimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Electrical and Formocresol Pulpotomy in Primary Molars
Status: TERMINATED
Conditions: Reversible Pulpitis|Caries
Interventions: PROCEDURE: Formocresol application after pulpotomy preparation|PROCEDURE: GENTLEray 980 Soft Tissue diode laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of Lachrymal Substitute Gels on Tear Film Thickness in Patients With Moderate to Severe Dry Eye Syndrome
Status: COMPLETED
Conditions: Dry Eye Syndromes
Interventions: DEVICE: Thealoz Duo Gel|DEVICE: Hylo-Gel|DEVICE: Systane Gel Drops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Cholangiography Using Carbon Dioxide Versus Iodinated Contrast in ERCP
Status: ACTIVE_NOT_RECRUITING
Conditions: Choledocholithiasis|Bile Duct Diseases|Bile Duct Carcinoma
Interventions: OTHER: "Air" contrast cholangiography using carbon dioxide gas
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Evaluate the Efficacy and Safety of Rivoceranib in Participants With Recurrent or Metastatic Adenoid Cystic Carcinoma (ACC)
Status: TERMINATED
Conditions: Adenoid Cystic Carcinoma
Interventions: DRUG: Rivoceranib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Safety and Efficacy of 5-aminolevulinic Acid Hydrochloride (5-ALA HCl) and Sodium Ferrous Citrate (SFC) Added on Artemisinin-based Combination Therapy (ACT) in Adult Patients With Uncomplicated Malaria
Status: WITHDRAWN
Conditions: Malaria
Interventions: DRUG: 5-aminolevulinic acid hydrochloride (5-ALA HCl) 600 mg QD|DRUG: Sodium ferrous citrate (SFC) 472 mg QD|DRUG: Artemisinin-based combination (ACT)|DRUG: Placebo|DRUG: 5-aminolevulinic acid hydrochloride (5-ALA HCl) 300 mg BID|DRUG: Sodium ferrous citrate (SFC) 236 mg BID
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: SKIP for PA Study: Team and Leadership Level Implementation Support for Collaborative Care
Status: RECRUITING
Conditions: Child Behavior Problem|Attention Deficit and Disruptive Behavior Disorders
Interventions: BEHAVIORAL: DOCC: Evidence-based treatment for disruptive behavior and ADHD|BEHAVIORAL: TEAM: Implementation support strategies at the care team level following standard implementation of DOCC|BEHAVIORAL: Implementation support strategies at the leadership level following standard implementation of DOCC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Vildagliptin in Combination With Pioglitazone in Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Vildagliptin|DRUG: pioglitazone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Is Repetitive Transcranial Magnetic Stimulation Effective in Reducing Endometriosis-associated Pain
Status: RECRUITING
Conditions: Endometriosis|Pain
Interventions: DEVICE: Real RepetitiveTranscranial Magnetic Stimulation 5 sessions|DEVICE: Sham RepetitiveTranscranial Magnetic Stimulation 5 sessions|DEVICE: Real RepetitiveTranscranial Magnetic Stimulation 10 sessions|DEVICE: Sham RepetitiveTranscranial Magnetic Stimulation 10 sessions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Efficacy of CR845 in Hemodialysis Patients With Moderate-to-Severe Pruritus (KALM-1)
Status: COMPLETED
Conditions: Uremic Pruritus
Interventions: DRUG: CR845 0.5 mcg/kg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Carboplatin, Capecitabine, and Radiation Therapy in Treating Patients With Stage III or Stage IV Head and Neck Cancer
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: DRUG: capecitabine|DRUG: carboplatin|PROCEDURE: conventional surgery|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Botulinum Toxin A & Weekly Serial Casting in ABI Inpatients With Lower Extremity Spasticity
Status: WITHDRAWN
Conditions: Spastic Foot
Interventions: DRUG: Botulinum toxin type A|DEVICE: Serial Casting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Anti-PD-1/PD-L1 Antibodies Plus S-adenosyl-methionine Treatment in Patients With Advanced-Stage Hepatocellular Carcinoma
Status: RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Anti-PD-1/PD-L1|DRUG: S-Adenosyl-Methionine
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Xenogenic Collagen Matrix for the Treatment of Multiple Gingival Recessions
Status: RECRUITING
Conditions: Gingival Recession, Generalized
Interventions: DEVICE: Use of XCM for the treatment of MAGRs with mCAF technique|PROCEDURE: Treatment of MAGRs with CTG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Selective Digestive Decontamination in the ICU With High Rates of Antibiotic-resistant Bacteria
Status: UNKNOWN
Conditions: Pneumonia, Ventilator-Associated|Pneumonia|Bloodstream Infection|Sepsis|Respiratory Distress Syndrome|Respiratory Tract Infections|Critical Illness
Interventions: DRUG: Oral Paste(0,5 g) containing 10 mg of polymyxin B, 10 mg of gentamycin and 150 mg of amphotericine B or 500 000 U of nistatin q6h|DRUG: Suspension (10 ml) containing 100 mg of polymyxin B, 80 mg of gentamycin, 350 mg of amphotericine B or 8000000 U of nistation and 500 mg of vancomycin q6h|DRUG: Intravenous Antibacterial Agent - a 3-day course of systemic cefotaxime 1 g q6h or ceftriaxone 1 g qd
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Combining Lovastatin and a Parent-Implemented Language Intervention for Fragile X Syndrome
Status: COMPLETED
Conditions: Fragile X Syndrome|Genetic Diseases
Interventions: DRUG: Lovastatin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Topical Cryotherapy in Reducing Pain in Patients With Chemotherapy Induced Peripheral Neuropathy or Paclitaxel Induced Acute Pain Syndrome
Status: COMPLETED
Conditions: Breast Carcinoma
Interventions: PROCEDURE: Cryotherapy|DRUG: Paclitaxel|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Bioavailability and Pharmacokinetic Study of Subcutaneous and Intravenous RO6811135 in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: RO6811135|DRUG: RO6811135
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Continuous Quality Improvement (CQI) Pilot Study Evaluating the Utility of an Educational Video
Status: COMPLETED
Conditions: Actinic Keratoses
Interventions: OTHER: Video Group|OTHER: Verbal Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Testing Multiple Behavioral Science Strategies to Increase Flu-Shot Rates
Status: COMPLETED
Conditions: Influenza, Human
Interventions: BEHAVIORAL: Flu shot text messages
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Phase I Study of [177Lu]Lu-EVS459 in Patients With Ovarian and Lung Cancers
Status: NOT_YET_RECRUITING
Conditions: Ovarian Cancer|Lung Cancer
Interventions: DRUG: [68Ga]Ga-EVS459|DRUG: [177Lu]Lu-EVS459
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cross-over Study to Prove Bioequivalence Between Two Brands of Cefalexin Capsules
Status: COMPLETED
Conditions: Anti-Infective Agents
Interventions: DRUG: Cephalexin capsules (Optocef, BAYO5448 )|DRUG: Cephalexin capsules (Keflex)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of TAK-771 in Japanese Participants With Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP) and Multifocal Motor Neuropathy (MMN)
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP)|Multifocal Motor Neuropathy (MMN)
Interventions: DRUG: TAK-771
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Study the Efficacy of PEG-IFN Alpha in HBeAg Negative Chronic Hepatitis B Patients After Stopping Nucleotide Analogue Therapy.
Status: UNKNOWN
Conditions: Hepatitis B
Interventions: DRUG: Peg IFN 2b
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Yoga in Relieving Fatigue in Patients Undergoing Chemotherapy for Ovarian Cancer
Status: TERMINATED
Conditions: Depression|Fatigue|Ovarian Cancer
Interventions: BEHAVIORAL: Home yoga practice|BEHAVIORAL: yoga classes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Efficacy and Safety of WELT-ED for Eating Disorder (WCTP-ED-B-01)
Status: RECRUITING
Conditions: Eating Disorders|Binge Eating|Binge-Eating Disorder
Interventions: DEVICE: WELT-ED (CBT based DTx)|BEHAVIORAL: Standard Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: McGRATH vs Macintosh Laryngoscopy Comparison in LMA Insertion
Status: COMPLETED
Conditions: Intubation Complication|Intubation;Difficult|Anesthesia
Interventions: DEVICE: McGRATH laryngoscopy|DEVICE: Macintosh laryngoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Capecitabine and Radiation Therapy in Treating Young Patients With Newly Diagnosed, Nonmetastatic Brain Stem Glioma or High-Grade Glioma
Status: COMPLETED
Conditions: Brain and Central Nervous System Tumors
Interventions: DRUG: capecitabine|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Drug-Drug Interaction Study to Assess the Effects of Steady State Pitavastatin 4 mg or Rosuvastatin 40 mg on Steady-State Warfarin in Healthy Adult Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Warfarin|DRUG: Warfarin 5mg + Rosuvastatin 40 mg once daily (QD)|DRUG: Warfarin 5 mg + Pitavastatin 4mg once daily (QD)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: The Use of Ranolazine for Atrial Fibrillation and Diastolic Heart Failure
Status: TERMINATED
Conditions: Atrial Fibrillation|Heart Failure
Interventions: DRUG: Ranolazine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Augmentation of Interpersonal Psychotherapy With High-Definition Transcranial Direct Current Stimulation for Adolescent Depression
Status: RECRUITING
Conditions: Depressive Disorder
Interventions: COMBINATION_PRODUCT: IPT plus HD-tDCS|COMBINATION_PRODUCT: IPT plus sham HD-tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pre-Emptive Analgesia Efficacy of Etoricoxib for Postoperative Pain
Status: COMPLETED
Conditions: a Single-Dose of Etoricoxib|Post-Operative Morphine Consumption|Total Pain Relief Over 8 Hr(TOPAR8)|Post Transabdominal Hysterectomy
Interventions: DRUG: a single-dose of Etoricoxib before induction of anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Use of a Mini-fluid Bolus to Identify Fluid Responsiveness
Status: WITHDRAWN
Conditions: Cardiac Output, Low|Cardiac Output, High
Interventions: PROCEDURE: Small fluid boluses of 50 ml|DEVICE: LIDCORapid Monitor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effectiveness Study of Single Photon Emission Computed Tomography (SPECT) Versus Positron Emission Tomography (PET) Myocardial Perfusion Imaging
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: PROCEDURE: Myocardial perfusion imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Left Cardiac Sympathetic Denervation for Cardiomyopathy Feasibility Pilot Study
Status: SUSPENDED
Conditions: Dilated Cardiomyopathy|Ischemic Cardiomyopathy|Non-ischemic Cardiomyopathy
Interventions: PROCEDURE: Left Cardiac Sympathetic Denervation (LCSD)|OTHER: Optimal Medical Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Prospective Study of The Complement Depletion in Patients With Severe Abdominal Sepsis
Status: COMPLETED
Conditions: Severe Sepsis|Pancreatitis|Abdominal Abscess|Appendicitis|Digestive System Fistula
Interventions: DRUG: Norepinephrine|PROCEDURE: Open abdomen|OTHER: enteral nutrition|OTHER: parenteral nutrition
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Patients Undergoing Laparoscopic Radical Gastrectomy Walk Out From Operating Room After Surgery ( WOFOR-G-01 )
Status: RECRUITING
Conditions: Laparoscopic Radical Gastrectomy|Enhanced Recovery After Surgery
Interventions: BEHAVIORAL: Walk out from operating room
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Continuous Positive Airway Pressure in Achieving Asthma Control in Patients With Severe Asthma and Obstructive Sleep Apnea
Status: UNKNOWN
Conditions: Severe Asthma With Obstructive Sleep Apnea
Interventions: DEVICE: Continuous Positive Airway Pressure
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preemptive TIPS for Variceal Bleeding in Cirrhotic Patients With Occlusive Portal Vein Thrombosis
Status: NOT_YET_RECRUITING
Conditions: Portal Hypertension|Portal Vein Thrombosis|Esophageal Varix Bleeding|Portosystemic Shunt
Interventions: PROCEDURE: preemptive TIPS|PROCEDURE: standard second prophylaxis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Program of Angiotensin-Neprilysin Inhibition in Admitted Patients With Worsening Heart Failure (PREMIER)
Status: ACTIVE_NOT_RECRUITING
Conditions: Heart Failure
Interventions: DRUG: Sacubitril Valsartan Sodium Hydrate|DRUG: Standard treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of a Bakery Product Enriched With Fibre and L-carnitine on Insulin Resistance in Patients With Metabolic Syndrome
Status: COMPLETED
Conditions: Metabolic X Syndrome|Overweight|Dyslipidemias
Interventions: DIETARY_SUPPLEMENT: dietary fibre plus L-carnitine bread|DIETARY_SUPPLEMENT: Placebo bread
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Multiple Dose Trial Comparing the Plasma Levels of Two Different Analgesic Transdermal Patch Formulations (Protocol ID: 855509)
Status: TERMINATED
Conditions: Healthy
Interventions: DRUG: Buprenorphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Achievement of Improved Survival by Molecular Targeted Chemotherapy and Liver Resection for Not Optimally Resectable Colorectal Liver Metastases
Status: COMPLETED
Conditions: Liver Only Metastasis From KRAS Exon 2 Wild Type (Under Protocol 1.0-1.2 Edition) and RAS Wild Type (Under Protocol 2.0 Edition) Colorectal Cancer
Interventions: DRUG: Bevacizumab|DRUG: Cetuximab|DRUG: L-OHP|DRUG: l-LV|DRUG: 5-FU|DRUG: 5-FU
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Deposits on Contact Lenses Worn Daily Wear
Status: COMPLETED
Conditions: Refractive Error
Interventions: DEVICE: Balafilcon A contact lenses (PureVision)|DEVICE: Etafilcon A contact lenses (Acuvue2)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: Efficacy and Safety of Artemether-Lumefantrine and Dihydroartemisinin-Piperaquine in Cameroon
Status: UNKNOWN
Conditions: Malaria
Interventions: DRUG: Artemether-Lumefantrine Drug Combination|DRUG: Dihydroartemisinin-Piperaquine drug combination
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Black Garlic Nutraceuticals and Blood Pressure Control
Status: UNKNOWN
Conditions: Hypertension
Interventions: DIETARY_SUPPLEMENT: ABG+ Black Garlin|DIETARY_SUPPLEMENT: Crystalline Cellulose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare P1101 Plus TAF With or Without UDCA in Patients With HBV and HDV Co-Infection
Status: NOT_YET_RECRUITING
Conditions: Hepatitis D
Interventions: DRUG: Ursodeoxycholic acid|DRUG: Ropeginterferon alfa-2b|DRUG: Tenofovir Alafenamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Programmed Intermittent Epidural Bolus Versus Continuous Infusion in Labour Analgesia
Status: RECRUITING
Conditions: Labor Pain
Interventions: DEVICE: Programmed intermittent epidural bolus|DEVICE: Continuous infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Indocyanine Green Fluorescent Cholangiography and Intraoperative Angiography With Laparoscopic Cholecystectomy
Status: COMPLETED
Conditions: Cholecystitis|Chronic Calculous Cholecystitis|Acute Calculous Cholecystitis
Interventions: PROCEDURE: Indocyanine Green Fluorescent Laparoscopic Cholangiography|PROCEDURE: White Light
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of SX-682 Plus Enzalutamide in Men With Abiraterone-Resistant Metastatic Castration Resistant Prostate Cancer
Status: RECRUITING
Conditions: Metastatic Castration-resistant Prostate Cancer
Interventions: DRUG: SX-682|DRUG: Enzalutamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Re-treatment With Sulfadoxine-pyrimethamine in Children
Status: COMPLETED
Conditions: Malaria, Falciparum
Interventions: DRUG: Sulfadoxine-pyrimethamine (Fansidar)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Albumin-Bound Paclitaxel and Gemcitabine in Patients With Untreated Stage IV or Recurrent Squamous Cell Lung Cancers
Status: COMPLETED
Conditions: Lung Cancer|Untreated Stage IV or Recurrent Squamous Cell Lung Cancers
Interventions: DRUG: albumin-bound paclitaxel|DRUG: gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Fitaya Vena Cava Filter
Status: UNKNOWN
Conditions: Venous Thromboembolism
Interventions: DEVICE: Fitaya Vena Cava Filter System|DEVICE: Aegisy Vena Cava Filter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HD11 for Intermediate Stages
Status: COMPLETED
Conditions: Hodgkin´s Lymphoma
Interventions: DRUG: Adriamycin|DRUG: Bleomycin|DRUG: Vinblastine|DRUG: DTIC|DRUG: Etoposide|DRUG: Procarbazine|DRUG: Prednisone|DRUG: Vincristine|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: QST for Corneal Nerve Function
Status: ENROLLING_BY_INVITATION
Conditions: Corneal Disease|Neuropathy|Dry Eye Disease|Neurotrophic Keratitis
Interventions: DEVICE: Quantitative Sensory Test
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Nasal Spray With Glucose Oxidase as a Treatment of Common Cold
Status: COMPLETED
Conditions: Common Cold
Interventions: DEVICE: Glucose oxidase+5%glucose|DEVICE: Saline+5%glucose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neonates and Azithromycin, an Innovation in the Treatment of Children in Burkina Faso
Status: COMPLETED
Conditions: Childhood Mortality
Interventions: DRUG: Azithromycin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Phase 1/2 Study to Evaluate OTX-2002 in Patients With Hepatocellular Carcinoma and Other Solid Tumor Types Known for Association With the MYC Oncogene
Status: RECRUITING
Conditions: Hepatocellular Carcinoma|Solid Tumor|Hepatocellular Carcinoma Non-resectable|Hepatocellular Carcinoma Recurrent|Hepatocellular Cancer|Liver Cancer|Liver, Cancer of, Non-Resectable
Interventions: DRUG: OTX-2002|DRUG: Tyrosine kinase inhibitor One|DRUG: Tyrosine kinase inhibitor Two|DRUG: Checkpoint Inhibitor, Immune
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pedicle Screws Placement Accuracy in Thoracolumbar Spine Using O-arm Navigation VS Standard Cervical Distractor Screws
Status: UNKNOWN
Conditions: Pedicle Screws|Surgery, Computer-Assisted/Adverse Effects|Bone Screws|Imaging, Three-Dimensional/Methods
Interventions: PROCEDURE: Pedicle screws instrumentation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bilateral Internal Jugular Veins Ultrasound Scanning Prior to CVC Placement
Status: COMPLETED
Conditions: Central Venous Catheterization|Ultrasonography|Critical Care
Interventions: PROCEDURE: Standard Practice|PROCEDURE: Bilateral IJ Ultrasound Scanning
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Controlled Trial of MRI Target Biopsy: Transrectal vs. Transperineal
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: PROCEDURE: Trans-rectal MRI targeted Biopsy|PROCEDURE: Trans-perineal MRI targeted Biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety and Efficacy of FLACS With the FEMTO LDV Z8 Laser Compared to Conventional Cataract Surgery in Chinese Patients
Status: COMPLETED
Conditions: Cataract
Interventions: DEVICE: Femtosecond Laser Assissted Cataract Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Deproteinised Calf Blood Serum Injection for the Treatment of Acute Intracerebral Hemorrhage
Status: UNKNOWN
Conditions: Intracerebral Hemorrhage
Interventions: DRUG: Deproteinised Calf Blood Serum Injection|DRUG: Placebo (Sodium Chloride)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Role of Chewing Gum in Reducing Post Operative Ileus After Reversal of Ileostomy
Status: COMPLETED
Conditions: Postoperative Ileus
Interventions: OTHER: Sugar Free Chewing Gum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Novel Technique Of Uterine Cooling During Repeated Cesarean Section For Reducing Blood Loss
Status: COMPLETED
Conditions: Cesarean Section Complications|Intrapartum Hemorrhage|Postpartum Hemorrhage|Atony, Uterine
Interventions: PROCEDURE: Uterine Cooling Technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Safety and Efficacy of Coenzyme I for Injection in Promoting Hematopoietic Recovery of Patients After sUCBT
Status: RECRUITING
Conditions: Hematopoietic Recovery
Interventions: DRUG: Coenzyme I for Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Distraction vs Interposition Arthroplasty for Basilar Thumb Osteoarthritis
Status: UNKNOWN
Conditions: Thumb Osteoarthritis
Interventions: PROCEDURE: Interposition Arthroplasty|PROCEDURE: Hematoma and Distraction Arthroplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial of TQA3038 Injection in Healthy Adult Subjects
Status: RECRUITING
Conditions: Chronic Hepatitis b
Interventions: DRUG: TQA3038 injection|DRUG: TQA3038 injection matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Family-Skills Training to Prevent Tobacco and Other Substance Use in Latino Youth
Status: COMPLETED
Conditions: Tobacco Use Disorder|Alcohol Use Disorder|Drug Use Disorder|Smoking|Alcohol Drinking|Drug Abuse
Interventions: BEHAVIORAL: Family-Skills Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Intravitreal Aflibercept Injection or Early Vitrectomy for Diabetic Vitreous Hemorrhage
Status: COMPLETED
Conditions: Diabetic Vitreous Hemorrhage
Interventions: DRUG: Aflibercept Injection [Eylea]|PROCEDURE: Vitrectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Identification and Treatment of Developmental Trochlear Femoral Dysplasia
Status: RECRUITING
Conditions: TROCLEAR DYSPLASIA
Interventions: DEVICE: pavlik harness
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT