pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Effect of Virtual Reality Distraction on Procedural Pain for Children and Adolescents in Onco-Hematology Unit.
Status: UNKNOWN
Conditions: Procedural Pain|Procedural Anxiety|Virtual Reality
Interventions: DEVICE: Virtual Reality Headset
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Transrectus Sheath Pre-peritoneal (TREPP) Technique for Strangulated Inguinal Hernia: a Case-series
Status: COMPLETED
Conditions: Strangulated Inguinal Hernia
Interventions: PROCEDURE: emergency transrectus sheath pre-peritoneal mesh repair (e-TREPP)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pharmacokinetics of Sugammadex (MK-8616) in Participants With Moderate and Severe Renal Insufficiency (MK-8616-105)
Status: COMPLETED
Conditions: Renal Insufficiency|Renal Impairment
Interventions: DRUG: sugammadex
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparision of Air Versus CO2 for Distention During Sigmoidoscopy
Status: TERMINATED
Conditions: Colorectal Surgery
Interventions: PROCEDURE: Air insufflation with standard endoscopy unit, CO2 insufflation for colonoscopy (special CO2 insufflation unit)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Assess the Tolerability of Oxylanthanum Carbonate in Patients With Chronic Kidney Disease on Dialysis
Status: COMPLETED
Conditions: Chronic Kidney Disease Requiring Chronic Dialysis
Interventions: DRUG: Oxylanthanum Carbonate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: "A Clinical Study Investigating the Effectiveness of OTC Scar-management Modalities"
Status: COMPLETED
Conditions: Scar|Keloid|Hypertrophic Scar|Cicatrix
Interventions: OTHER: Placebo Cream Base Emulsion Moisturizer|OTHER: FS2 Emulsion Moisturizer|OTHER: Active Comparator Onion Skin Extract Gel (Mederma)|OTHER: Active Comparator Silicone Gel (Kelo-Cote)|OTHER: Active Comparator Silicone Gel (Kelo-Cote) + FS2 Emulsion Moisturizer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Acupuncture as a Complementary Therapy for in Vitro Fertilization Patients: a Randomized Controlled Trial
Status: UNKNOWN
Conditions: Acupuncture|Quality of Life|Infertility|Stress|Anxiety
Interventions: OTHER: Acupuncture|OTHER: Questionnaires
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SRS Timing With Immune Checkpoint Inhibition in Patients With Untreated Brain Metastases From Non-small Cell Lung Cancer
Status: WITHDRAWN
Conditions: Brain Metastases|Non Small Cell Lung Cancer
Interventions: RADIATION: Stereotactic Radiosurgery|DRUG: Immunotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing the Outcome of Anterior Lumbar Fusion and Total Lumbar Disc Replacement
Status: WITHDRAWN
Conditions: Disc Disease Degenerative|Disk Degeneration|Disc Disease Lumbar
Interventions: PROCEDURE: Anterior Lumbar Interbody Fusion|PROCEDURE: Total Disc Replacement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Adverse Events, Change in Disease Activity, and How Intravenously Infused ABBV-319 Moves Through the Bodies of Adult Participants With Relapsed or Refractory (R/R) Diffuse Large B-cell Lymphoma (DLBCL), Follicular Lymphoma (FL), or Chronic Lymphocytic Leukemia (CLL)
Status: RECRUITING
Conditions: Diffuse Large B-Cell Lymphoma|Chronic Lymphocytic Leukemia|Follicular Lymphoma
Interventions: DRUG: ABBV-319
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial Investigating the Safety and Effects of One or Two Additional Doses of Comirnaty or One Dose of BNT162b2s01 in BNT162-01 or BNT162-04 Trial Subjects
Status: COMPLETED
Conditions: COVID-19|SARS-CoV-2 Infection
Interventions: BIOLOGICAL: BNT162b2s01|BIOLOGICAL: BNT162b2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Anti-inflammatory Therapy for Recurrent In-stent Restenosis
Status: NOT_YET_RECRUITING
Conditions: In-stent Restenosis
Interventions: DRUG: Colchicine|DRUG: Prednisone|DRUG: Aspirin|DRUG: P2Y12 Receptor Antagonist|DRUG: Lipid-lowering drug
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chemoprophylaxis and Plasmodium Falciparum NF54 Sporozoite Immunization Challenged by Heterologous Infection
Status: COMPLETED
Conditions: Malaria
Interventions: BIOLOGICAL: CPS-immunization|BIOLOGICAL: malaria challenge infection, P. falciparum NF135.C10|BIOLOGICAL: malaria challenge infection, P. falciparum NF166.C8|BIOLOGICAL: malaria challenge infection, P. falciparum NF54|DRUG: atovaquone/proguanil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Therapeutic Effects of Pine Bark Extracts in Attention Deficit Hyperactivity Disorder
Status: COMPLETED
Conditions: ADHD
Interventions: DIETARY_SUPPLEMENT: Oligopin®|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pharmacokinetic Study of Vancomycin, Clindamycin and/or Gentamicin Administration During Surgery Using a Microdialysis Procedure
Status: RECRUITING
Conditions: Surgical Site Infection
Interventions: OTHER: Blood and microdialysis samples
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Thalidomide and Prednisone Following Peripheral Stem Cell Transplantation in Treating Patients With Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma and Plasma Cell Neoplasm
Interventions: DRUG: prednisone|DRUG: thalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Interaction of Epanova on Warfarin Pharmacokinetic and Anticoagulant Activity and Comparison of the Effects of Epanova and Lovaza on Eicosapentaenoic Acid (EPA) and Docosahexaenoic Acid (DHA) After Low-fat Meals
Status: COMPLETED
Conditions: Hypertriglyceridemia
Interventions: DRUG: warfarin|DRUG: omefas|DRUG: omega-3-acid ethyl esters
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Methylphenidate in Improving Cognition and Function in Older Adults With Depression
Status: COMPLETED
Conditions: Depression
Interventions: DRUG: Citalopram|DRUG: Methylphenidate (MPH)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Open-Label, Uncontrolled Clinical Trial of Oral 566C80 for the Treatment of Patients With Severe PCP Who Are Intolerant and/or Unresponsive to Therapy With Trimethoprim/Sulfamethoxazole and Parenteral Pentamidine
Status: COMPLETED
Conditions: Pneumonia, Pneumocystis Carinii|HIV Infections
Interventions: DRUG: Atovaquone
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Development of the Palate in Bilateral Orofacial Cleft Newborns One Year After Early Neonatal Cheiloplasty
Status: UNKNOWN
Conditions: Cleft Palate|Cleft Lip|Cleft Lip and Palate|Cleft Lip, Bilateral
Interventions: PROCEDURE: Early neonatal cheiloplasty
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Nitazoxanide Tablets in the Treatment of Mild to Moderate Active Crohn's Disease
Status: TERMINATED
Conditions: Crohn's Disease
Interventions: DRUG: Nitazoxanide|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effective OnabotulinumtoxinA Dose Response Study for Upper Facial Wrinkles
Status: WITHDRAWN
Conditions: Rhytides
Interventions: DRUG: OnabotulinumtoxinA Standard Dose|DRUG: OnabotulinumtoxinA Half Standard Dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: ABSORB FIRST is a Registry Designed to Evaluate the Safety and Performance of Absorb Bioresorbable Vascular Scaffold (Absorb BVS) Used in Real-world Patients.
Status: COMPLETED
Conditions: Chronic Total Occlusion of Coronary Artery|Coronary Occlusion|Coronary Artery Disease|Coronary Artery Restenosis|Coronary Artery Stenosis|Coronary Disease|Coronary Restenosis
Interventions: DEVICE: Absorb Bioresorbable Vascular Scaffold
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Clinical Trial to Study the Effect and Safety of Rotavirus Vaccine Against Severe Rotavirus Gastroenteritis in Healthy Indian Infants
Status: COMPLETED
Conditions: Rotavirus Gastroenteritis
Interventions: BIOLOGICAL: Live Attenuated Pentavalent (G1-G2-G3-G4-G9) Human X Bovine Reassortant Rotavirus Vaccine (BRV-PV)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Ondansetron on Gastrointestinal Sensorimotor Dysfunctions in Diabetes Mellitus and Dyspepsia
Status: RECRUITING
Conditions: Indigestion|Diabetes Mellitus
Interventions: DRUG: Ondansetron 8mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Speech Therapy and Repetitive Transcranial Magnetic Stimulation Therapy in Post-stroke Anomic Aphasia
Status: COMPLETED
Conditions: Aphasia|Aphasia, Anomic|Stroke
Interventions: DEVICE: Repetitive transcranial magnetic stimulation|OTHER: Speech therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: TVT Versus TOT in Urinary Stress Incontinence With No Intrinsic Sphincter Deficiency
Status: COMPLETED
Conditions: Female Urinary Stress Incontinence
Interventions: PROCEDURE: TVT surgery TOT surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: NR in Chemo-induced Peripheral Neuropathy
Status: TERMINATED
Conditions: Chemotherapy-induced Peripheral Neuropathy|Breast Cancer Metastatic|Platinum-resistant Recurrent Ovarian Cancer|Head and Neck Cancer Stage IV|Endometrial Cancer Stage IV
Interventions: DRUG: Nicotinamide Riboside
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Look at How Safe Insulin NNC0471-0119 is and How it Works in People With Type 1 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: DRUG: NNC0471-0119|DRUG: Fast-acting insulin aspart
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Postoperative Return to Sexual Activity
Status: RECRUITING
Conditions: Sexual Function Disturbances|Pelvic Organ Prolapse|Stress Urinary Incontinence|Surgery
Interventions: OTHER: Structured Counselling Tool
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Beneficial Effects of Pomegranate on Hearing of Patients Without Hemodialysis
Status: COMPLETED
Conditions: Hearing Impairment
Interventions: DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: Pomegranate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of the Effects of External Electrical Stimulation Protocols in Women With Overactive Bladder
Status: NOT_YET_RECRUITING
Conditions: Overactive Bladder
Interventions: OTHER: Electrical stimulation 1|OTHER: Electrical stimulation 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial for People With Established Type 2 Diabetes During Ramadan
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: Liraglutide|DRUG: Liraglutide|DRUG: Sulfonylurea or Pioglitazone|DRUG: Maintain dual therapy (Sulf/Pio) as comparator to Liraglutide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Induction Gemcitabine & Carboplatin Followed by Paclitaxel & Carboplatin +XRT in NSCLC
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DRUG: Gemcitabine|DRUG: Carboplatin|DRUG: Paclitaxel|PROCEDURE: Radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tiragolumab, Atezolizumab and Chemotherapy in Triple Negative Breast Cancer
Status: RECRUITING
Conditions: Triple Negative Breast Cancer
Interventions: RADIATION: 68Ga-FAPI-46 PET/CT|BIOLOGICAL: Tumor samples analysis|BIOLOGICAL: Blood samples analysis: Circulating Tumor DNA
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study to Evaluate the Safety and Effectiveness of Novabel Bioabsorbable Steroid-releasing Stent for the Chronic Sinusitis
Status: RECRUITING
Conditions: Chronic Sinusitis
Interventions: DEVICE: bioabsorbable steroid-releasing stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II Study of Pencil Beam Scanning Proton Stereotactic Body Radiation Therapy for Prostate Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Cancer
Interventions: RADIATION: Pencil Beam Scanning Proton SBRT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open-label Study to Evaluate Metreleptin in Children Under 6 Years of Age With Generalised Lipodystrophy
Status: RECRUITING
Conditions: Generalized Lipodystrophy
Interventions: DRUG: Metreleptin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tislelizumab Combined With Neoadjuvant Radiotherapy and Chemotherapy for Resectable Esophageal Squamous Cell Carcinoma.
Status: RECRUITING
Conditions: Advanced Esophageal Squamous Cell Cancer
Interventions: DRUG: Tislelizumab Combined With Neoadjuvant Radiotherapy and Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Listen Carefully: An Exploratory Study of the Association Between Listening Effort and Cognitive Function
Status: COMPLETED
Conditions: Cognitive Impairment, Mild|Hearing Loss
Interventions: DEVICE: Oticon Opn S 1 miniRITE hearing aid
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effects of Short-term Scapular Control Training in Overhead Athletes With Shoulder Impingement Syndrome
Status: COMPLETED
Conditions: Shoulder Impingement Syndrome|Scapular Dyskinesis
Interventions: PROCEDURE: Scapular control training|PROCEDURE: General exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Impact of Interactive, Multifaceted Approach Education on Congenital Cataract
Status: UNKNOWN
Conditions: Congenital Cataract
Interventions: OTHER: interactive, multifaceted approach|OTHER: conventional approach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Immediate Implant Placement With Sticky Tooth Versus Autogenous Tooth Graft In Cases With Labial Plate Dehiscence
Status: NOT_YET_RECRUITING
Conditions: Immediate Implant
Interventions: PROCEDURE: immediate implant augmented with sticky tooth|PROCEDURE: immediate implant augmented with autogenous tooth graft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Couple-Based Motivational Interviewing With Mobile Breathalyzers to Reduce Alcohol Use in South Africa
Status: ACTIVE_NOT_RECRUITING
Conditions: HIV/AIDS|Alcohol Abuse
Interventions: BEHAVIORAL: Motivational Interviewing|BEHAVIORAL: Motivational Interviewing plus Breathalyzer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Ultra-High Resolution Optical Coherence Tomography in Detecting Micrometer Sized Early Stage Pancreatic Cancer in Participants With Pancreatic Cancer
Status: RECRUITING
Conditions: Pancreatic Carcinoma|Pancreatic Intraductal Papillary Mucinous Neoplasm, Pancreatobiliary-Type
Interventions: PROCEDURE: Optical Coherence Tomography|PROCEDURE: Therapeutic Conventional Surgery|DIAGNOSTIC_TEST: Laboratory Evaluation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Doripenem in the Treatment of Complicated Lower Urinary Tract Infection or Pyelonephritis
Status: COMPLETED
Conditions: Urinary Tract Infections|Pyelonephritis
Interventions: DRUG: doripenem
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Suicidal Ideation With Intravenous Ketamine Infusion
Status: COMPLETED
Conditions: Depression|Suicidal Ideation
Interventions: DRUG: Ketamine|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Development of a Diagnostic Prediction Score for Tuberculosis in Hospitalized Children With Severe Acute Malnutrition
Status: UNKNOWN
Conditions: Tuberculosis|Severe Acute Malnutrition
Interventions: OTHER: Development of a score and algorithm for TB treatment decision in hospitalised children with SAM.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Cognitive AED Outcomes in Pediatric Localization Related Epilepsy (COPE)
Status: TERMINATED
Conditions: Epilepsy, Partial|Epilepsy, Localization Related
Interventions: DRUG: Oxcarbazepine|DRUG: Levetiracetam|DRUG: Lamotrigine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Role of Endomyocardial Biopsy and Aetiology-based Treatment in Patients With Inflammatory Heart Disease in Arrhythmic and Non-arrhythmic Clinical Presentations: an Integrated Approach for the Optimal Diagnostic and Therapeutic Management
Status: RECRUITING
Conditions: Myocarditis|Ventricular Arrythmia|Inflammatory Cardiomyopathy|Genetic Predisposition|Autoimmunity|Arrhythmia|Cardiomyopathies|Immunosuppression|Catheter Ablation
Interventions: OTHER: support treatment, cardiac medical treatment, aetiology-specific treatment, device implant, arrhythmia ablation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Six Month Study to Evaluate the Safety and Effectiveness of the Intranasal Lacrimal Neurostimulator
Status: COMPLETED
Conditions: Dry Eye Syndromes|Keratoconjunctivitis Sicca
Interventions: DEVICE: Intranasal Lacrimal Neurostimulator (Oculeve)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study to Characterise the Effect of Tamsulosin on Lower Urinary Tract Symptoms (LUTS) and Detrusor Motor Activity in Patients Affected by Benign Prostatic Hyperplasia (BPH) and Storage Urinary Symptoms
Status: COMPLETED
Conditions: Prostatic Hyperplasia
Interventions: DRUG: Tamsulosin HCl controlled release capsules|DRUG: Matching placebo capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Peripheral Nerve Catheter Securement Techniques at the Insertion Site in Healthy Volunteers
Status: COMPLETED
Conditions: Regional Anesthesia Morbidity
Interventions: OTHER: Dressing|OTHER: Dressing + adhesive|OTHER: Experimental: Dressing + adhesive + strips (parallel)|OTHER: Experimental: Dressing + adhesive + strips (perpend)|OTHER: Experimental: Dressing + adhesive + strips + benzoin|OTHER: Experimental: Dressing + adhesive + strips + spray
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Back to ECE Safely With SAGE: Reducing COVID-19 Transmission in Hispanic and Low-income Preschoolers
Status: UNKNOWN
Conditions: COVID-19 Testing|Children, Preschool|Parents|Child Development|Self-Control|Exercise|Diet, Healthy
Interventions: BEHAVIORAL: CHILD back-to-ECE COVID-19 saliva testing|BEHAVIORAL: ECE personnel back-to-ECE COVID-19 saliva screening|BEHAVIORAL: SAGE garden programming
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparison of Different Methods of Controlling Pain During Debonding of Orthodontic Brackets
Status: COMPLETED
Conditions: Analgesia|Orthodontic Appliance Complication
Interventions: OTHER: Stabilization of teeth during debonding using fingure pressure and elastic wafer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Randomized Multicentric Trial to Evaluate a Free Diet With a Progressive Diet in the Treatment of Acute Diverticulitis (DIVERDIET)
Status: COMPLETED
Conditions: Diverticulitis|Acute Diverticulitis|Diverticulitis, Colonic|Uncomplicated Diverticular Disease|Diverticulitis of Sigmoid|Diet Modification|Dietary Modification
Interventions: OTHER: Free diet|OTHER: Progressive diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Intranasal Administration of Avacc 10 Vaccine Against COVID-19 in Healthy Volunteers
Status: COMPLETED
Conditions: COVID-19
Interventions: BIOLOGICAL: Avacc 10|COMBINATION_PRODUCT: Outer Membrane Vesicles (OMV) : OMV alone in vehicle|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Neugranin in Breast Cancer Participants Receiving Doxorubicin/Docetaxel
Status: COMPLETED
Conditions: Chemotherapy-induced Neutropenia
Interventions: BIOLOGICAL: Neugranin|BIOLOGICAL: Pegfilgrastim|DRUG: Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Gene Transfer Clinical Trial to Deliver rAAVrh74.MCK.GALGT2 for Duchenne Muscular Dystrophy
Status: ACTIVE_NOT_RECRUITING
Conditions: Duchenne Muscular Dystrophy
Interventions: BIOLOGICAL: rAAVrh74.MCK.GALGT2
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Safety and Tolerability of High Lipid and Calorie Supplementation in Amyotrophic Lateral Sclerosis
Status: COMPLETED
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DIETARY_SUPPLEMENT: Calogen|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pre-operative Trial for Breast Cancer With Nivolumab in Combination With Novel IO
Status: RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Nivolumab|DRUG: Ipilimumab|DRUG: Ipilimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rollover Study of Ivacaftor in Subjects With Cystic Fibrosis and a Non G551D CFTR Mutation
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: Ivacaftor
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Investigation to Assess the Performance of the Eureka Electric Breast Pump in Mothers Breastfeeding Their Healthy Term Infant
Status: COMPLETED
Conditions: Breast Pumping
Interventions: DEVICE: Using Eureka Breast Pump with Expression Kit
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MLC901 in Hypoxic-ischemic Brain Injury Patients; A Double-blind, Randomized Placebo-controlled Trial
Status: COMPLETED
Conditions: Hypoxic Ischaemic Encephalopathy Due to Cardiac Arrest
Interventions: DRUG: MLC 901|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dual Growth Factor (rhTPO + G-CSF) and Chemotherapy Combination Regimen in Acute Myeloid Leukemia: Study Protocol for a Randomized Controlled Trial
Status: RECRUITING
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: rhTPO|DRUG: Decitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Antipsychotic Efficacy of Cannabidiol in Acute Schizophrenic Psychosis
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Cannabidiol|DRUG: Amisulpride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Topical Dynamic Phototherapy on the Microbiota of Chronic Wounds
Status: COMPLETED
Conditions: Leg Ulcer
Interventions: PROCEDURE: Topical Dynamic Phototherapy (TDP)|DRUG: Metvixia cream
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Study of the HCV Protease Inhibitor Bo-cePRevir and the Proton Pump Inhibitor OMeprazOle (PROMO)
Status: COMPLETED
Conditions: HCV Infections|Gastric Acid-related Disorders
Interventions: DRUG: boceprevir|DRUG: Omeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Safety and Immune Response to a Multi-component Immune Based Therapy (MKC1106-MT) for Patients With Melanoma.
Status: COMPLETED
Conditions: Advanced Melanoma|Stage III and IV Melanoma
Interventions: BIOLOGICAL: Biological: MKC1106-MT|BIOLOGICAL: Biological: MKCC1106-MT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acute and Chronic Effect of 250 mg Citicoline Consumption on Attention in Adults: A Randomized Trial
Status: COMPLETED
Conditions: Attention
Interventions: DIETARY_SUPPLEMENT: Active capsule|OTHER: Placebo capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study to Examine Clinical Performance and Safety of Cutimed® Gelling Fiber in Routine Clinical Practice
Status: COMPLETED
Conditions: Leg Ulcer|Diabetic Foot Ulcer|Pressure Ulcer|Surgical Wound|Abrasion|Laceration|Burn, Partial Thickness|Oncology Wound
Interventions: DEVICE: Cutimed® Gelling Fiber
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of the Efficacy of Different Drugs in the Treatment of the Pain in Patients With Temporomandibular Disorder
Status: COMPLETED
Conditions: Temporomandibular Disorder
Interventions: DRUG: Dexketoprofen Trometamol + Thiocolchicoside|DRUG: Dexketoprofen Trometamol + Paracetamol|DRUG: Dexketoprofen Trometamol (25mg)|DRUG: Paracetamol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Post Extraction Changes Following Ridge Preservation Using Partially Demineralized Dentin Block Versus L- PRF Block
Status: RECRUITING
Conditions: Socket Preservation
Interventions: BIOLOGICAL: Partially Demineralized Dentin Block|BIOLOGICAL: L-PRF block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Soy Isoflavones and Breast Cancer Risk Reduction
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DIETARY_SUPPLEMENT: isoflavones|DIETARY_SUPPLEMENT: carbohydrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mild-Intensity Whole Body Hyperthermia (WBH) for Major Depressive Disorder
Status: SUSPENDED
Conditions: Major Depressive Disorder
Interventions: DRUG: Tocilizumab|DRUG: Placebo|DEVICE: Whole-Body Hyperthermia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Knee Arthroplasty Rehabilitation Outcomes Study
Status: COMPLETED
Conditions: Total Knee Arthroplasty|Rehabilitation
Interventions: OTHER: Anti-gravity treadmill|OTHER: PENS - neuro-muscular stimulation|OTHER: Anti-gravity treadmill & PENS - neuro-muscular stimulation|OTHER: Recumbent or Nu-step bike
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Examination of the Acute Effect of Mollii Suit in Children With Cerebral Palsy
Status: RECRUITING
Conditions: Mollii Suit|Cerebral Palsy
Interventions: OTHER: Molli Suit Apply
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Diet on Chronic Inflammation and Related Disorders Following Spinal Cord Injury
Status: COMPLETED
Conditions: Neuropathic Pain|Depression|Cognitive Impairment|Somatic Neuropathy|Autonomic Dysfunction
Interventions: DIETARY_SUPPLEMENT: Omega-3|DIETARY_SUPPLEMENT: Vegetation Protein Powder|DIETARY_SUPPLEMENT: InflanNox|DIETARY_SUPPLEMENT: Anti-oxidant Network|DIETARY_SUPPLEMENT: Chlorella
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of the Usefulness of Hemopatch in Coronary Artery Bypass Graft Surgery
Status: UNKNOWN
Conditions: CHD - Coronary Heart Disease
Interventions: DEVICE: Medical Device Hemopatch-PEG-coated collagen patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A One-stop Shop for the Same Day Diagnosis and Management of TB and HIV
Status: COMPLETED
Conditions: Tuberculosis|Hiv
Interventions: DIAGNOSTIC_TEST: CRP and Molbio Truenat MTB|DIAGNOSTIC_TEST: CRP and Xpert ULTRA MTB/RIF|DIAGNOSTIC_TEST: standard test Xpert|DIAGNOSTIC_TEST: Culture as reference standard
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of Response-Guided Duration of Combination Therapy With GS-9451, Pegasys® and Copegus® With and Without Tegobuvir (GS-9190) in Previously Untreated Subjects With Genotype 1 Chronic Hepatitis C
Status: COMPLETED
Conditions: Hepatitis C, Chronic
Interventions: DRUG: Tegobuvir (GS-9190)|DRUG: GS-9451|BIOLOGICAL: Pegasys®|DRUG: Copegus®|DRUG: GS-9451|DRUG: Tegobuvir placebo|BIOLOGICAL: Pegasys®|DRUG: Copegus®|DRUG: Tegobuvir placebo|DRUG: GS-9451 placebo|BIOLOGICAL: Pegasys®|DRUG: Copegus®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Personalized Escalation of Consolidation Treatment Following Chemoradiotherapy and Immunotherapy in Stage III NSCLC in Stage III NSCLC
Status: RECRUITING
Conditions: Non Small Cell Lung Cancer|NSCLC, Stage III|Nsclc
Interventions: DRUG: Durvalumab|DRUG: Carboplatin|DRUG: Pemetrexed|DRUG: Paclitaxel|DRUG: Cisplatin|DEVICE: AVENIO ctDNA Surveillance Kit|DRUG: Tremelimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Eplerenone in the Management of Abdominal Aortic Aneurysms
Status: UNKNOWN
Conditions: Aortic Aneurysm, Abdominal
Interventions: DRUG: Eplerenone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 3-AP and Cytarabine in Treating Patients With Hematologic Cancer
Status: COMPLETED
Conditions: Leukemia|Myelodysplastic Syndromes|Myelodysplastic/Myeloproliferative Neoplasms
Interventions: DRUG: cytarabine|DRUG: triapine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Clozapine for the Prevention of Violence in Schizophrenia: a Randomized Clinical Trial
Status: RECRUITING
Conditions: Schizophrenia|Schizoaffective Disorder
Interventions: DRUG: Clozapine|DRUG: treatment as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Dexmedetomidine Premedication on Geriatric Patients With Chronic Renal Failure Undergoing Hip Surgery
Status: COMPLETED
Conditions: Chronic Renal Failure|Hip Fracture
Interventions: DRUG: dexmedetomidine infusion for premedication|DRUG: Midazolam|DRUG: saline infusion|DRUG: Spinal block with hyperbaric bupivacaine 0.5% 12.5 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: RCT of an Internet Cessation Program Plus Online Social Network for HIV+ Smokers
Status: COMPLETED
Conditions: Tobacco Use Disorder|HIV
Interventions: BEHAVIORAL: PSFW+|BEHAVIORAL: AHA|DRUG: Nicotine polacrilex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Epidemiological Study Of The Prevalence Of HLA-B*5701 In HIV-1 Infected Patients
Status: COMPLETED
Conditions: Infection, Human Immunodeficiency Virus I|HIV Infection|HIV-1 Infection
Interventions: PROCEDURE: Cheek cells sample|PROCEDURE: Blood sample
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Somnage® in the Management on Sleep and Mood in Cancer Patients
Status: TERMINATED
Conditions: Breast Cancer|Lung Cancer|Colon Cancer
Interventions: DIETARY_SUPPLEMENT: Somnage|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: TakeCharge: Telephone Delivered Self-management Intervention for People With Multiple Sclerosis (MS)
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: BEHAVIORAL: Self-management intervention|BEHAVIORAL: Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Tolerability of Symbicort as an add-on Treatment to Spiriva Compare With Spiriva Alone in Patients With Severe Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: DRUG: Budesonide/formoterol (Symbicort® Turbuhaler®)|DRUG: Tiotropium (SpirivaTM)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Ceiling Fans for Mitigating Thermal Strain During Bed Rest in Older Adults During Heat Waves
Status: RECRUITING
Conditions: Hyperthermia|Heat Stress|Cooling|Aging
Interventions: OTHER: No cooling (control)|OTHER: Cooling with ceiling fan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Phase 1 Study to Examine the Effect of Renvela on the Pharmacodynamics of AZD1722
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: AZD1722|DRUG: Renvela
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Relationship Between Muscle Strength,Anaerobic,Aerobic Capacity,and Sportive Performance in WC Basketball Athletes
Status: COMPLETED
Conditions: Sports Physical Therapy
Interventions: DIAGNOSTIC_TEST: Aerobic Capacity
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Pharmacokinetics And Pharmacodynamics Of Lapatinib In Two Dosing Regimens In Treatment-naive Patients With Breast Cancer
Status: COMPLETED
Conditions: Neoplasms, Breast
Interventions: DRUG: lapatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Elsamitrucin (SPI 28090) for Relapsed or Refractory Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Mantle Cell Lymphoma|Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma
Interventions: DRUG: Elsamitrucin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Approach Bias Modification for the Treatment of Cannabis Use Disorder
Status: COMPLETED
Conditions: Cannabis Use Disorder
Interventions: BEHAVIORAL: Approach Bias Modification (ABM)|BEHAVIORAL: Sham ABM|BEHAVIORAL: Psychosocial therapy for cannabis use disorder.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Integrins and Protocadherins in Glutamatergic Circuits: Identification of Common Signaling Pathways and Molecular Targets in Anxiety and Major Depressive Disorders (GAPsy)
Status: RECRUITING
Conditions: Depression, Anxiety|Healthy
Interventions: DIAGNOSTIC_TEST: GAPsy protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effect of Oral Caffeine and L-Citrulline Supplementation on Arterial Function in Healthy Males
Status: COMPLETED
Conditions: Hypertension|Healthy
Interventions: DRUG: Caffeine|DRUG: Placebo|DIETARY_SUPPLEMENT: L-citrulline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Hypotonic Hyponatremia: Criteria for the Correct Classification of Its Etiology and of Patient Volume Status
Status: COMPLETED
Conditions: Hyponatremia|Hyponatremia With Extracellular Fluid Depletion|Hyponatremia With Normal Extracellular Fluid Volume|Hyponatremia With Excess Extracellular Fluid Volume
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Post-Marketing Non-Acute Safety Study in Japan After Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) mRNA-1273 COVID-19 Vaccine in Persons at High Risk of Severe COVID-19
Status: COMPLETED
Conditions: SARS-CoV-2
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: An Inpatient Advance Care Planning Intervention for Older Patients With Hematologic Malignancies
Status: RECRUITING
Conditions: Hematologic Malignancies
Interventions: BEHAVIORAL: Inpatient serious illness care program
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Clinical and Immunohisochemical Evaluation of Chemopreventive Effect of Thymoquinone on Oral Potentially Malignant Lesions.
Status: COMPLETED
Conditions: Premalignant Lesion
Interventions: DRUG: Nigella sativa buccal tablets 10mg|DRUG: Nigella sativa buccal tablets 5mg|DRUG: Placebo buccal tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use of 3-D Blood Pool Scintigraphy to Guide Left Ventricular Pacing Lead Placement in Patients Requiring Cardiac Resynchronization Therapy
Status: TERMINATED
Conditions: Heart Failure|Left Ventricular Dysfunction|Cardiac Resynchronization Therapy
Interventions: OTHER: Guided|OTHER: Non-guided
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase III Clinical Trial to Determine the Safety and Efficacy of ZF2001 for Prevention of COVID-19
Status: UNKNOWN
Conditions: Prevention of COVID-19|Safety and Efficacy
Interventions: BIOLOGICAL: Recombinant new coronavirus vaccine (CHO cell) group|BIOLOGICAL: Recombinant new coronavirus vaccine (CHO cells) placebo group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Dentinal Hypersensitivity Reduction
Status: COMPLETED
Conditions: Dentinal Hypersensitivity
Interventions: DRUG: Colgate SNF|DRUG: Sensodyne Extra Whitening|DRUG: Colgate Fluoride (CDC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Safety of TBCB vs TBFB in Diagnosis of GGO
Status: UNKNOWN
Conditions: Lung Ground-Glass Opacity
Interventions: PROCEDURE: Transbronchial Cryobiopsy|PROCEDURE: Transbronchial Forceps Biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Pharmacokinetics and Tolerability of Meloxicam Injected Intramuscularly vs. Tablet in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Meloxicam ampoule|DRUG: Meloxicam tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Unilateral Deep Brain Stimulation (DBS) of the Nucleus (Nucl.) Accumbens (Acc.) in Patients With Treatment Resistant Obsessive Compulsive Disorder (OCD)
Status: COMPLETED
Conditions: Obsessive Compulsive Disorder
Interventions: PROCEDURE: Deep Brain Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing the Effectiveness of EndoRotor Versus Radiofrequency in Treating Barrett's Esophagus
Status: RECRUITING
Conditions: Barrett Esophagus|Dysplasia
Interventions: DEVICE: Endorotor|DEVICE: Radiofrequency
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multiple Dose Escalation Study (14 Days) to Investigate Safety, Tolerability, PK and PD of Vardenafil and BAY60-4552
Status: COMPLETED
Conditions: Erectile Dysfunction
Interventions: DRUG: BAY60-4552 + Vardenafil|DRUG: BAY60-4552 + Vardenafil|DRUG: BAY60-4552 + Vardenafil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: DSM265 Phase IIa Investigation Treating Plasmodium Falciparum or Vivax
Status: COMPLETED
Conditions: Plasmodium Falciparum Malaria|Plasmodium Vivax Malaria
Interventions: DRUG: DSM265 400mg|DRUG: DSM265 xmg|DRUG: DSM265 ymg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BRE-10: Biomarker Optimization of Neoadjuvant Therapy in Breast Cancer
Status: RECRUITING
Conditions: Breast Cancer|HER2-positive Breast Cancer
Interventions: DRUG: Paclitaxel|DRUG: Nab-paclitaxel|DRUG: Docetaxel|DRUG: Trastuzumab|DRUG: Pertuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long Term Prospective Study of Tai Chi Intervention to Prevent MCI From Conversion to Dementia
Status: NOT_YET_RECRUITING
Conditions: Mild Cognitive Impairment
Interventions: BEHAVIORAL: Tai chi training|BEHAVIORAL: Group activity
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION