pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Metformin With the Levonorgestrel-Releasing Intrauterine Device for the Treatment of Complex Atypical Hyperplasia (CAH) and Endometrial Cancer (EC) in Non-surgical Patients
Status: COMPLETED
Conditions: Complex Atypical Hyperplasia|Endometrial Cancer
Interventions: DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dietary Essential Fatty Acid Regulation of Omega-3 HUFA Metabolism; Satiety and Body Composition
Status: COMPLETED
Conditions: Weight Gain|Healthy Subjects|Obesity|Women
Interventions: DIETARY_SUPPLEMENT: Linoleic Acid|DIETARY_SUPPLEMENT: Docosahexaenoic Acid|DIETARY_SUPPLEMENT: Eicosapentaenoic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: Effects of Bedside Compared to Outside the Room Case Presentation
Status: COMPLETED
Conditions: Bedside Patient Case Presentation|Outside-the-room Patient Case Presentation
Interventions: PROCEDURE: patient case presentation bedside|PROCEDURE: patient case presentation Outside-the-room
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Immunotherapy Using Cyclosporine, Interferon Gamma, and Interleukin-2 After High-Dose Myeloablative Chemotherapy With Autologous Stem Cell Transplantation in Treating Patients With Refractory or Relapsed Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: BIOLOGICAL: aldesleukin|BIOLOGICAL: filgrastim|BIOLOGICAL: recombinant interferon gamma|DRUG: carmustine|DRUG: cyclosporine|DRUG: cytarabine|DRUG: etoposide|DRUG: melphalan|PROCEDURE: autologous bone marrow transplantation|PROCEDURE: bone marrow ablation with stem cell support|PROCEDURE: peripheral blood stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lymphocyte Infusion in Treating Patients With Relapsed Cancer After Bone Marrow or Peripheral Stem Cell Transplantation
Status: COMPLETED
Conditions: Breast Cancer|Chronic Myeloproliferative Disorders|Gestational Trophoblastic Tumor|Kidney Cancer|Leukemia|Lymphoma|Multiple Myeloma and Plasma Cell Neoplasm|Myelodysplastic Syndromes|Neuroblastoma|Ovarian Cancer|Sarcoma|Testicular Germ Cell Tumor
Interventions: BIOLOGICAL: peripheral blood lymphocyte therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Study of AR-67 (DB-67) in Myelodysplastic Syndrome (MDS)
Status: UNKNOWN
Conditions: Myelodysplastic Syndrome
Interventions: DRUG: AR-67 (20S)-7-t-Butyldimethylsilyl-10-hydroxycamptothecin)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Extension to QTI571A2301 to Evaluate the Long-term Safety, Tolerability and Efficacy of Imatinib in Severe Pulmonary Arterial Hypertension (PAH)
Status: TERMINATED
Conditions: Pulmonary Arterial Hypertension
Interventions: DRUG: Imatinib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SER-109 Versus Placebo to Prevent Recurrent Clostridium Difficile Infection (RCDI)
Status: COMPLETED
Conditions: Clostridium Difficile
Interventions: DRUG: SER-109|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: SIMPLE Chemotherapy for NK Lymphoma/Leukaemia
Status: UNKNOWN
Conditions: Non-Hodgkin's Lymphoma, Relapsed|Non-Hodgkin T-cell Lymphoma|Natural Killer/T-Cell Lymphoma, Nasal and Nasal-Type
Interventions: DRUG: Cisplatin|DRUG: Gemcitabine|DRUG: Etoposide (VP-16)|DEVICE: Ifosfamide|DRUG: Dexamethasone|DRUG: L-asparaginase
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral Astaxanthin and Semen Quality, Fertilization and Embryo Development in Assisted Reproduction Techniques Procedures
Status: COMPLETED
Conditions: Infertility, Male
Interventions: DIETARY_SUPPLEMENT: astaxanthin with vitamin E|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Supplementation of L-arginine in Patients With Non-resectable Brain Metastases
Status: COMPLETED
Conditions: Unresectable Multiple Brain Metastases
Interventions: DIETARY_SUPPLEMENT: L-arginine hydrochloride solution|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Tegavivint for Treating Patients With Relapsed or Refractory Large B-Cell Lymphoma
Status: RECRUITING
Conditions: Recurrent Diffuse Large B-Cell Lymphoma Activated B-Cell Type|Recurrent Diffuse Large B-Cell Lymphoma Germinal Center B-Cell Type|Recurrent High Grade B-Cell Lymphoma With MYC and BCL2 or BCL6 Rearrangements|Recurrent High Grade B-Cell Lymphoma With MYC, BCL2, and BCL6 Rearrangements|Refractory Diffuse Large B-Cell Lymphoma Activated B-Cell Type|Refractory Diffuse Large B-Cell Lymphoma Germinal Center B-Cell Type|Refractory High Grade B-Cell Lymphoma With MYC and BCL2 or BCL6 Rearrangements|Refractory High Grade B-Cell Lymphoma With MYC, BCL2, and BCL6 Rearrangements|Transformed Indolent B-Cell Non-Hodgkin Lymphoma to Diffuse Large B-Cell Lymphoma
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|PROCEDURE: Positron Emission Tomography|DRUG: Tegavivint
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Immunotherapy With TIL (Tumor Infiltrating Lymphocytes) in Combination With Intra-tumoral Injections of Interferon Gamma-adenovirus (Ad-IFNg) in Patients With Stage IIIc or Stage IV Metastatic Melanoma (AJCC)(Protocol TIL-Ad-INFg)
Status: TERMINATED
Conditions: Metastatic Melanoma
Interventions: OTHER: TIL-Ad-INFg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study in Healthy Volunteers to Investigate the Safety, Tolerability and Pharmacokinetics of VM-1500
Status: COMPLETED
Conditions: HIV-infection
Interventions: DRUG: VM-1500|DRUG: Darunavir|DRUG: Ritonavir|DRUG: Raltegravir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Study of Lopinavir Based ART for HIV Infected childreN Globally (LIVING Study)
Status: COMPLETED
Conditions: HIV
Interventions: DRUG: LPV/RTV pellets and AZT/3TC or ABC/3TC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bevacizumab Combined With Gefitinib in the Treatment of Advanced NSCLC
Status: UNKNOWN
Conditions: PFS
Interventions: DRUG: Gefitinib|DRUG: Bevacizumab Combined With Gefitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: the Application of Cardiopulmonary Exercise Testing in Assessment Outcome of Patients With Pulmonary Hypertension
Status: RECRUITING
Conditions: Pulmonary Hypertension|Chronic Thromboembolic Pulmonary Hypertension|Pulmonary Arterial Hypertension Associated With Schistosomiasis (Disorder)
Interventions: DEVICE: balloon pulmonary angioplasty
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Fallopian Tube Sperm Perfusion (FSP) Versus Intra-uterine Insemination (IUI) in Natural Cycle
Status: COMPLETED
Conditions: Insemination, Artificial
Interventions: PROCEDURE: Fallopian tube sperm perfusion|PROCEDURE: Intrauterine insemination using standard catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Development and Assessment of a Spanish-Language Hearing Loss Toolkit for Self-Management
Status: RECRUITING
Conditions: Hearing Loss
Interventions: OTHER: Spanish-Language Hearing Loss Toolkit for Self-Management|OTHER: American Speech-Language-Hearing Association (ASHA) Audiology Series Spanish Language Handouts
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Bioelectrical Impedance Phase Angle in Predicting Treatment Outcome in Patients With Extensive Stage Small Cell Lung Cancer Receiving First-Line Chemotherapy
Status: TERMINATED
Conditions: Extensive Stage Small Cell Lung Cancer
Interventions: PROCEDURE: bioelectric impedance analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Concomitant Tricuspid Repair in Patients With Left Heart Surgery
Status: NOT_YET_RECRUITING
Conditions: Tricuspid Regurgitation|Mitral Regurgitation|Cardiopulmonary Bypass
Interventions: DEVICE: Tricuspid repair
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of Oral Sapacitabine to Treat Acute Myeloid Leukemia in Elderly Patients
Status: COMPLETED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Sapacitabine, Arm A|DRUG: Sapacitabine, Arm B|DRUG: Sapacitabine, Arm C|DRUG: Sapacitabine, Arm D|DRUG: sapacitabine, Arm E|DRUG: sapacitabine, Arm F|DRUG: Sapacitabine, Arm G|DRUG: Sapacitabine, Arm H|DRUG: Sapacitabine, Arm I
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MiCo - Mirena or Conventional Medical Treatment for Menorrhagia
Status: COMPLETED
Conditions: Idiopathic Menorrhagia
Interventions: DRUG: Levonorgestrel (Mirena, BAY86-5028)|DRUG: Hormonal treatment|DRUG: Antifibrinolytic treatment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: "Nuestras Historias": Evaluating the Impact of Community-Created Digital Stories on Pre- and Perinatal Health Motivation in the Peruvian Amazon
Status: COMPLETED
Conditions: Health Knowledge, Attitudes, Practice|Maternal Behavior
Interventions: BEHAVIORAL: "Nuestras Historias"
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Extracranial Carotid & Intracranial Arterial Stenosis in Ischemic Stroke
Status: UNKNOWN
Conditions: Ischemic Stroke|Carotid Stenosis
Interventions: OTHER: Carotid duplex+/- MRA neck|OTHER: brain MRA+/-CT angio on carotid and brain|OTHER: MRI brain|OTHER: DSA (digital subtraction angiography)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Treatment Comparison of Antibiotics Versus Vaginal Lactic Acid in Non-pregnant Women With Acute Symptomatic Bacterial Vaginosis
Status: COMPLETED
Conditions: Bacterial Vaginosis
Interventions: DEVICE: Vaginal lactic acid and glycogen gel|DRUG: Metronidazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exercise, Cancer and Cognition: The ECCO-Study
Status: RECRUITING
Conditions: Breast Cancer
Interventions: PROCEDURE: High-Intensity-Interval-Training|PROCEDURE: General Physical Activity Recommendations
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phase II Trial of Fecal Microbiota Transplant (FMT) for VRE and CRE Patients
Status: WITHDRAWN
Conditions: Clostridium Difficile Infection
Interventions: DRUG: FMT Capsule DE|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Compound Danshen Dripping Pills to Treat Acute Mountain Sickness
Status: COMPLETED
Conditions: Acute Mountain Sickness
Interventions: DRUG: Placebo|DRUG: Compound danshen dripping pills
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Exercise on Distress, Quality of Life, and Biomarkers in Ovarian Cancer Survivors
Status: TERMINATED
Conditions: Ovarian Cancer|Fallopian Tube Adenocarcinoma|Fallopian Tube Carcinosarcoma|Fallopian Tube Clear Cell Adenocarcinoma|Fallopian Tube Endometrioid Adenocarcinoma|Fallopian Tube Mucinous Adenocarcinoma|Fallopian Tube Serous Adenocarcinoma|Fallopian Tube Transitional Cell Carcinoma|Fallopian Tube Undifferentiated Carcinoma|Malignant Ovarian Brenner Tumor|Ovarian Adenocarcinoma|Ovarian Carcinosarcoma|Ovarian Clear Cell Adenocarcinoma|Ovarian Endometrioid Adenocarcinoma|Ovarian Mucinous Adenocarcinoma|Ovarian Seromucinous Carcinoma|Ovarian Serous Adenocarcinoma|Ovarian Transitional Cell Carcinoma|Ovarian Undifferentiated Carcinoma|Primary Peritoneal Serous Adenocarcinoma|Primary Peritoneal Carcinosarcoma|Primary Peritoneal Transitional Cell Carcinoma
Interventions: OTHER: Exercise Counseling|OTHER: Aerobic Exercise|OTHER: Physiological Support|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration|OTHER: Best Practice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Observational Study Of The Long-Term Effect Of Macugen In Patients With Wet Age-Related Macular Degeneration
Status: COMPLETED
Conditions: Macular Degeneration|Age-related Macular Degeneration|Neovascular Macular Degeneration
Interventions: DRUG: Pegaptanib
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Strategic Ingestion of Creatine Supplementation and Resistance Training in Trained Young Adults
Status: RECRUITING
Conditions: Strength|Muscle
Interventions: DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: Creatine monohydrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Study of AZD5069 and Enzalutamide.
Status: TERMINATED
Conditions: Metastatic Castration Resistant Prostate Cancer
Interventions: DRUG: AZD5069|DRUG: Enzalutamide 40 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study on Impact of Canagliflozin on Health Status, Quality of Life, and Functional Status in Heart Failure
Status: COMPLETED
Conditions: Heart Failure
Interventions: DRUG: Canagliflozin 100 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy and Total-Body Irradiation Before Donor Umbilical Cord Blood Transplant in Treating Patients With Advanced Hematologic Cancer, Metastatic Breast Cancer, or Kidney Cancer
Status: COMPLETED
Conditions: Breast Cancer|Kidney Cancer|Leukemia|Lymphoma|Multiple Myeloma and Plasma Cell Neoplasm|Myelodysplastic Syndromes
Interventions: DRUG: anti-thymocyte globulin|DRUG: cyclophosphamide|DRUG: cyclosporine|DRUG: fludarabine phosphate|DRUG: mycophenolate mofetil|PROCEDURE: radiation therapy|PROCEDURE: umbilical cord blood transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hyaluronic Acid Evaluation as Adjuvant to Temporomandibular Joint Arthroscopy
Status: COMPLETED
Conditions: Temporomandibular Joint Disc Displacement|Temporomandibular Joint Disorders
Interventions: BIOLOGICAL: Hyaluronic Acid|PROCEDURE: Temporomandibular Joint Arthroscopy|DRUG: Antibiotic therapy|DRUG: corticosteroid|DRUG: Antiinflammatories|DRUG: Analgesics|OTHER: Exercise program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Panitumumab-IRDye800 to Detect Pediatric Neoplasms During Neurosurgical Procedures
Status: NOT_YET_RECRUITING
Conditions: Brain Tumor
Interventions: DRUG: Panitumumab-IRDye800|DEVICE: Pinpoint-IR9000 endoscopic/handheld device|DEVICE: Explorer Air camera|DEVICE: PDE-NEO-II
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Gynecological Sentinel Lymph Nodes CEUS
Status: RECRUITING
Conditions: Cervical Carcinoma|Malignant Female Reproductive System Neoplasm|Vaginal Carcinoma|Vulvar Carcinoma
Interventions: DRUG: Perflubutane Microbubble|PROCEDURE: Contrast-Enhanced Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effect of Personal Protective Aids on Hypertension and Diabetes in People Exposed to High Levels of Air Pollution
Status: UNKNOWN
Conditions: Pollution; Exposure|HTN|Diabetes Mellitus
Interventions: DEVICE: N95 Mask/Indoor air purifier: Including sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Retrograde Femoral Nail-Advanced Outcomes for Fixation of Distal Femur and Femoral Shaft Fractures
Status: RECRUITING
Conditions: Femoral Fracture
Interventions: PROCEDURE: RFN-Advanced Retrograde Femoral Nailing System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Feasibility and Effectiveness of an Additional Resistance and Balance Training in Cardiac Rehabilitation of Older Patients After Valve Surgery or Intervention
Status: COMPLETED
Conditions: Frailty Syndrome|Quality of Life|Valve Heart Disease
Interventions: OTHER: Additional balance and resistance training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial Looking at Rituximab and Chemotherapy as a Treatment for Follicular Lymphoma in Elderly Patients
Status: UNKNOWN
Conditions: Follicular Lymphoma
Interventions: DRUG: Rituximab|DRUG: Cyclophosphamide|DRUG: Vincristine|DRUG: Prednisolone|DRUG: Fludarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Efficacy Study of JNJ-39220675 and Pseudoephedrine in Participants With Allergic Rhinitis
Status: COMPLETED
Conditions: Allergic Rhinitis
Interventions: OTHER: Placebo|DRUG: JNJ-39220675|DRUG: Pseudoephedrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Zuojin Wan Combined With Woonosan Fumarate for the Treatment of GRD Combined With Depression
Status: NOT_YET_RECRUITING
Conditions: Gastroesophageal Reflux Disease|Depression
Interventions: DRUG: Vonorasan Fumarate|DRUG: Zuojin Pills
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Randomized,International Multi-center Clinical Trial of RIF Plus RA for Non-high-risk APL
Status: UNKNOWN
Conditions: Acute Promyelocytic Leukaemia
Interventions: DRUG: Compound Realgar-Indigo Naturalis Formula Plus Retinoic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Densah Burs vs. Electrical Mallet in Closed Sinus Lifting.
Status: NOT_YET_RECRUITING
Conditions: Alveolar Bone Loss
Interventions: DEVICE: Electrical mallet|DEVICE: Osseo-densification burs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transoral Incisionless Fundoplication (TIF) for Laryngopharyngeal Reflux (LPR) Patients
Status: WITHDRAWN
Conditions: Gastroesophageal Reflux Disease (GERD)|Laryngopharyngeal Reflux (LPR)|Reflux Disease, Gastro-Esophageal|Motility Disorder
Interventions: DEVICE: Transoral Incisionless Fundoplication
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Does Intravenous Cannabis Reduce Postoperative Nausea and Vomiting (PONV)?
Status: TERMINATED
Conditions: Nausea|Vomiting
Interventions: DRUG: THC 9-d-tetra hydro cannabinol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Trial of Disposable Nitrous Oxide Canisters in Providing Pain Control During Burn Dressing Changes
Status: RECRUITING
Conditions: Burns|Pain, Acute
Interventions: DRUG: Nitrous Oxide Inhalant Product|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Anti-CTLA4-NF mAb (BMS986218), Nivolumab, and Stereotactic Body Radiation Therapy for the Treatment of Metastatic Solid Malignancies
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Lung Carcinoma|Advanced Malignant Solid Neoplasm|Malignant Adrenal Gland Neoplasm|Metastatic Liver Carcinoma|Metastatic Lung Carcinoma|Metastatic Malignant Solid Neoplasm|Stage III Liver Cancer|Stage III Lung Cancer AJCC v8|Stage IIIA Lung Cancer AJCC v8|Stage IIIB Lung Cancer AJCC v8|Stage IIIC Lung Cancer AJCC v8|Stage IV Liver Cancer|Stage IV Lung Cancer AJCC v8|Stage IVA Liver Cancer|Stage IVA Lung Cancer AJCC v8|Stage IVB Liver Cancer|Stage IVB Lung Cancer AJCC v8
Interventions: BIOLOGICAL: Anti-CTLA4 Monoclonal Antibody BMS-986218|BIOLOGICAL: Nivolumab|RADIATION: Stereotactic Body Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Personalized Cognitive Integrated Motor Training Using Virtual Reality to Improve Gait and Balance
Status: NOT_YET_RECRUITING
Conditions: Traumatic Brain Injury
Interventions: OTHER: Personalized cognitive-sensorimotor VR/AR training|OTHER: Traditional dual-task training|OTHER: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Weekly Clofarabine for the Treatment of Relapsed/Refractory Chronic Lymphocytic Leukemia
Status: TERMINATED
Conditions: Chronic Lymphocytic Leukemia|Leukemia
Interventions: DRUG: Clofarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ER+/HER2- Locally Advanced or Metastatic Breast Cancer (ENZENO Study)
Status: UNKNOWN
Conditions: Estrogen Receptor-Positive|HER2-Negative|Locally Advanced Breast Cancer|Metastatic Breast Cancer
Interventions: DRUG: ZB716|DRUG: Palbociclib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tailored Treatment in Metastatic Colorectal Cancer
Status: TERMINATED
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: Capecitabine, Irinotecan, 5-Fluorouracil+Calciumfolinat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Safety and Tolerability of Everolimus in Combination With Reduced Exposure Cyclosporine or Tacrolimus in Paediatric Liver Transplant Recipients.
Status: COMPLETED
Conditions: Renal Function|Liver Transplant
Interventions: DRUG: Introduction of everolimus with reduced cyclosporine or tacrolimus dose, the earliest 1 month and the latest 6 months after liver transplantation.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of LY3819253 (LY-CoV555) and LY3832479 (LY-CoV016) in Preventing SARS-CoV-2 Infection and COVID-19 in Nursing Home Residents and Staff
Status: COMPLETED
Conditions: COVID-19|SARS-CoV2
Interventions: DRUG: Bamlanivimab|DRUG: Placebo|DRUG: Etesevimab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Filgrastim Compared With Sargramostim Plus Chemotherapy, Peripheral Stem Cell Transplantation, and Interferon Alfa in Treating Patients With Multiple Myeloma
Status: TERMINATED
Conditions: Multiple Myeloma and Plasma Cell Neoplasm
Interventions: DRUG: carmustine|DRUG: cyclophosphamide|DRUG: dexamethasone|DRUG: etoposide|DRUG: filgrastim|DRUG: mitoxantrone hydrochloride|DRUG: recombinant interferon alfa|DRUG: sargramostim|PROCEDURE: bone marrow ablation with stem cell support|PROCEDURE: peripheral blood stem cell transplantation|PROCEDURE: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Treatment of Erectile Dysfunction in Hypogonadal Men With Testosterone Undecanoate
Status: UNKNOWN
Conditions: Erectile Dysfunction|Hypogonadotrophic Males
Interventions: DRUG: Testosterone Undecanoate and/or PDE-5
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Impact of a Transitional Care Management Programme on the Migration Stress of Family Members of Patients
Status: RECRUITING
Conditions: Stress
Interventions: PROCEDURE: EICU Transfer Routine Care|PROCEDURE: Implementing interventions based on a 'health care-family-environment' linkage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Shotblocker and Breastfeeding on Pain/Comfort During Heel Lance
Status: COMPLETED
Conditions: Pain, Acute|Comfort
Interventions: BEHAVIORAL: breastfeeding|COMBINATION_PRODUCT: Breastfeeding and Shotblocker|DEVICE: shotblocker
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Dietary Effects on Circulating Lipoprotein-associated Phospholipase A2 (Lp-PLA2) Activity and Enzyme Activity in Peripheral Blood Mononuclear Cells (PBMCs) in Patients With Prediabetes or Newly Diagnosed Type 2 Diabetes
Status: COMPLETED
Conditions: Impaired Fasting Glucose|Newly Diagnosed Type 2 Diabetes
Interventions: DIETARY_SUPPLEMENT: Dietary intervention-whole grains and legumes|DIETARY_SUPPLEMENT: Dietary intervention-Refined rice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Self Defining Memories in Women Victims of Intimate Partner Violence.
Status: UNKNOWN
Conditions: Domestic Violence
Interventions: BEHAVIORAL: Assessment measures MINI, PCL5 and BDI-II and definition of 5 SDM|BEHAVIORAL: Assessment measures MINI and definition of 5 SDM
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: TUMORAPA 1: Efficacy of Rapamycin in Secondary Prevention of Skin Cancers in Kidney Transplant Recipients
Status: COMPLETED
Conditions: Skin Cancer|Kidney Transplantation
Interventions: DRUG: rapamycin|DRUG: ciclosporine|DRUG: tacrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Corticosteroid Combining Noncorticosteroid Systemic Immunomodulatory Therapy in VKH
Status: RECRUITING
Conditions: Vogt Koyanagi Harada Disease (VKH)
Interventions: DRUG: noncorticosteroid systemic immunomodulatory therapy (NCSIT)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Probiotic Modulates Vaginal Microflora
Status: COMPLETED
Conditions: Microbial Colonization
Interventions: DIETARY_SUPPLEMENT: Probiotic|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Capecitabine 7/7 Schedule With Neratinib in Patients With Metastatic HER2-Positive Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Capecitabine|DRUG: Neratinib|BEHAVIORAL: EORTC QLQ - BR23, EQ-5D-5L, EORTC QLQ-C30
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Betaine for Reduction of Urine Oxalate in Patients With Type 1 Primary Hyperoxaluria
Status: COMPLETED
Conditions: Hyperoxaluria
Interventions: DRUG: Betaine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Recombinant Human Platelet-Activating Factor Acetylhydrolase for the Treatment of Severe Sepsis
Status: TERMINATED
Conditions: Sepsis
Interventions: DRUG: rPAF-AH
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of RDX5791 in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: RDX5791|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: EFFECT ON QUALITY OF LIFE AFTER PROSTATECTOMY
Status: COMPLETED
Conditions: PROSTATECTOMY|URINARY INCONTINENCE
Interventions: OTHER: PELVIC FLOOR EXERCISES
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effects of Somatostatin on Post-endoscopic Portal Hemodynamic in Cirrhotic Patients With Esophageal Gastric Varices
Status: UNKNOWN
Conditions: Esophageal Varices Secondary to Cirrhosis of Liver
Interventions: DRUG: Somatostatin|PROCEDURE: endoscopic therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Sleep and Daytime Use of Humidified Nasal High-flow Oxygen in COPD Outpatients
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive|Hypercapnia|Hypoxia
Interventions: DEVICE: Humidified nasal high flow with oxygen
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Panitumumab, Nab-paclitaxel and Carboplatin for HER2 Negative Inflammatory Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Panitumumab|DRUG: Nab-paclitaxel|DRUG: Carboplatin|DRUG: 5-Fluorouracil|DRUG: Epirubicin|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Internet-Delivered Cognitive Behaviour Therapy for PTSD Among Public Safety Personnel
Status: RECRUITING
Conditions: Posttraumatic Stress|Depression|Anxiety
Interventions: BEHAVIORAL: PSP PTSD Course|BEHAVIORAL: PSP Wellbeing Course
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EFFECT OF A SUBSTANCE P ANTAGONIST ON THE SECRETION OF ALDOSTERONE IN PATIENTS WITH OBSTRUCTIVE SLEEP APNEA SYNDROME AND ARTERIAL HYPERTENSION
Status: RECRUITING
Conditions: Apnea, Obstructive
Interventions: DRUG: Aprepitant 125 and 80Mg Oral Capsule|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Stereotactic Radiosurgery (SRS) Dose-Escalation Study for Brain Metastasis
Status: RECRUITING
Conditions: Brain Neoplasms, Adult, Malignant
Interventions: RADIATION: Stereotactic Radiosurgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial Investigating the Chemotherapeutic Compound Treosulfan (Trecondi® Ideogen) in Myeloma Patients
Status: RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: Treosulfan|DRUG: Melphalan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pain, Discomfort, and Functional Impairments During Maxillary Expansion
Status: COMPLETED
Conditions: Constriction
Interventions: DEVICE: The bonded McNamara-type appliance|DEVICE: The removable palatal expansion appliance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Efficacy and Safety of a Fixed-dose, Single-capsule Budesonide-formoterol Combination in Uncontrolled Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Fixed combination of budesonide and formoterol|DRUG: Budesonide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Increased Adsorption Membranes During Cardiopulmonary Bypass
Status: COMPLETED
Conditions: Cardiopulmonary Bypass|Cardiac Surgery Associated - Acute Kidney Injury|Systemic Inflammatory Response Syndrome|Acute Kidney Injury
Interventions: DEVICE: oXiris®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Prophylactic Anticoagulation for Preventing Deep Vein Thrombosis After Total Hip Arthroplasty
Status: COMPLETED
Conditions: Deep Vein Thrombosis
Interventions: OTHER: prophylactic anticoagulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Spontaneous Laughter in the Postoperative Treatment of Children
Status: UNKNOWN
Conditions: Pain
Interventions: OTHER: Laughter therapy|OTHER: Accompaniment without causing the laughter of children.|DRUG: Conventional treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Bevacizumab for Symptomatic Vestibular Schwannoma in Neurofibromatosis Type 2 (NF2)
Status: COMPLETED
Conditions: Vestibular Schwannoma|Neurofibromatosis Type 2
Interventions: BIOLOGICAL: bevacizumab|OTHER: laboratory biomarker analysis|PROCEDURE: quality-of-life assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mind-Body Skills Groups for Behavioral and Emotional Problems in War-Traumatized Male Adolescents in Gaza
Status: COMPLETED
Conditions: Problem Behavior|Aggression|Posttraumatic Stress Disorder
Interventions: BEHAVIORAL: Mind-Body Skills Groups
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Menstrual Blood Stem Cells in Severe Covid-19
Status: COMPLETED
Conditions: Covid19|Cytokine Storm
Interventions: BIOLOGICAL: Allogeneic human menstrual blood stem cells secretome|OTHER: Intravenous saline injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Multi-Center Study Subjects With Dry Eye Syndrome
Status: COMPLETED
Conditions: Dry Eye Syndrome
Interventions: DRUG: EBI-005-2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Irbesartan on Insulin Sensitivity in Chronic Heart Failure
Status: COMPLETED
Conditions: Chronic Heart Failure
Interventions: DRUG: Irbesartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Pharmacokinetics of QAK423A in Healthy Volunteers and Chronic Obstructive Pulmonary Disease (COPD) Patients
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: QAK423A|DRUG: QAK423A|DRUG: QAK423A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: fMRI Study to Investigate Hemodynamic Changes in Brain Resulting From Supplementation of Bacopa Monnieri Extract and Multiple Micronutrient Supplementation.
Status: COMPLETED
Conditions: Growth and Development
Interventions: DIETARY_SUPPLEMENT: Beverage powder fortified with Bacopa Monnieri Extract and Multiple Micronutrient supplementation|DIETARY_SUPPLEMENT: Non-fortified isocaloric beverage powder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Understanding the Late Effects of Surviving a Pediatric Brain Tumor
Status: ACTIVE_NOT_RECRUITING
Conditions: Brain Tumor|Pediatric Brain Tumor|Pediatric Cancer
Interventions: DIAGNOSTIC_TEST: Diffusion tensor imaging (DTI)|DIAGNOSTIC_TEST: Resting state functional connectivity MRI (rs-fcMRI)|BEHAVIORAL: Wechsler Intelligence Scale for Children - 5th edition (WISC-V)|BEHAVIORAL: California Verbal Learning Test (CVLT-C)|BEHAVIORAL: Beery Test of Visual Motor Integration 6th edition|BEHAVIORAL: Grooved Pegboard|BEHAVIORAL: PedsQL Multidimensional Fatigue Scale|DIAGNOSTIC_TEST: MRI
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Long-term Telerehabilitation for Patients With Stroke
Status: COMPLETED
Conditions: Stroke|Cerebrovascular Disorders|Brain Diseases|Central Nervous System Diseases|Nervous System Diseases|Vascular Diseases
Interventions: DEVICE: Telerehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness and Cost-effectiveness of Surgical Treatment of Humeral Shaft Fractures. Randomized Controlled Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Fracture
Interventions: DEVICE: Conservative treatment|PROCEDURE: Operative treatment|OTHER: Physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Anti-cancer MUC1-specific Immunotherapy for Unresectable Stage III Non-small Cell Lung Cancer
Status: WITHDRAWN
Conditions: Non-small Cell Lung Cancer (NSCLC) Stage III
Interventions: OTHER: Biological: MUC1 peptide specific immunotherapy|DRUG: Cyclophosphamide (CPA)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluating the Safety, Tolerability, Pharmacokinetics, and Effect of Food of Lucid-21-302 in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DRUG: Lucid-21-302|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Relative Bioavailability Study of Ambrisentan and Tadalfil Fixed Dose Combination Tablets in Healthy Subjects
Status: COMPLETED
Conditions: Hypertension, Pulmonary
Interventions: DRUG: FDC (ambrisentan 10 mg-tadalafil 40 mg) single dose|DRUG: Reference (ambrisentan 10 mg + tadalafil 40 mg given concurrently)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pemetrexed Disodium in Treating Patients With Recurrent or Persistent Low-Risk Gestational Trophoblastic Tumor After a Molar Pregnancy
Status: TERMINATED
Conditions: Gestational Trophoblastic Tumor
Interventions: DRUG: pemetrexed disodium
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ADDITIVE BENEFITS OF KALTENBORN SUSTAINED STRETCH JOINT MOBILIZATION WITH RESISTANCE EXERCISE TRAINING IN KNEE OSTEOARTHRITIS
Status: ENROLLING_BY_INVITATION
Conditions: Knee Osteoarthritis
Interventions: PROCEDURE: Resistance Exercise Training|PROCEDURE: Joint Mobilization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Postoperative Atrial Fibrillation - Comparison of Amiodarone and Placebo.
Status: UNKNOWN
Conditions: Atrial Fibrillation
Interventions: DRUG: Amiodarone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: E-max CAD Crowns Retained With Fiber Reinforced Composite Post Versus E-max CAD Endocrowns
Status: UNKNOWN
Conditions: Tooth Fractures|Debonding
Interventions: PROCEDURE: E-max CAD endocrown|PROCEDURE: E-max CAd crowns retained with fiber reinforced composite post
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Thin and Ultrathin Bronchoscopy With Transbronchial Needle Aspiration and Radial Probe Endobronchial Ultrasound for Peripheral Pulmonary Lesions
Status: RECRUITING
Conditions: Peripheral Pulmonary Nodules
Interventions: DEVICE: BF-P190 4 mm thin bronchoscope|DEVICE: BF-MP190F 3 mm ultrathin bronchoscope|DEVICE: Radial ultrasound probe (UM S20-17S)|DEVICE: PeriView FLEX 21G Single Use Aspiration Needle
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Celecoxib as Adjuvant Therapy to Chemotherapy in Patients With Metastatic Colorectal Cancer
Status: RECRUITING
Conditions: Colon Cancer Stage
Interventions: DRUG: FOLFERI|DRUG: Folferi and celecoxib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Three-way-cross-over Study to Evaluate Safety and Pharmacokinetics of Lacosamide in Healthy Japanese and Chinese Males
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Lacosamide|DRUG: Lacosamide|DRUG: Lacosamide|OTHER: Placebo 3|OTHER: Placebo 4|OTHER: Placebo 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Study of Social Cognition by Morphological and Functional Imaging in Multiple Sclerosis Patients
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: OTHER: Brain MRI - Clinical and cognitive evaluation|DEVICE: MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Feasibility of a Supportive Education Program for Latina Breast Cancer Survivors
Status: TERMINATED
Conditions: Cancer Survivor|Stage I Breast Cancer|Stage II Breast Cancer|Stage IIIA Breast Cancer|Stage IIIB Breast Cancer|Stage IIIC Breast Cancer
Interventions: OTHER: Educational Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Taping to Control Edema in Patients With Forearm Plaster for Wrist Fracture.
Status: COMPLETED
Conditions: Edema Arm|Fracture; Wrist
Interventions: DEVICE: Tape application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Investigations of Botanicals on Food Intake, Satiety, Weight Loss, and Oxidative Stress
Status: TERMINATED
Conditions: Obesity|Oxidative Stress
Interventions: DIETARY_SUPPLEMENT: Microcrystalline Cellulose placebo pill|DIETARY_SUPPLEMENT: Garcinia cambogia-derived hydroxycitric acid (2800 mg/day)|DIETARY_SUPPLEMENT: Garcinia Cambogia derived Hydroxycitric Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: TINI 2: Total Therapy for Infants With Acute Lymphoblastic Leukemia II
Status: RECRUITING
Conditions: Lymphoblastic Leukemia
Interventions: DRUG: Dexamethasone|DRUG: Mitoxantrone|DRUG: PEG asparaginase|DRUG: Bortezomib|DRUG: Vorinostat|DRUG: Mercaptopurine|DRUG: Methotrexate|DRUG: Blinatumomab|DRUG: Ziftomenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare the Pharmacokinetics of Fimasartan/Atorvastatin Combination Tablet
Status: COMPLETED
Conditions: Hypertension|Hyperlipidemia
Interventions: DRUG: Fimasartan/Atorvastatin Combination Tablet|DRUG: Fimasartan|DRUG: Atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Myocardial Function by Speckle Tracking After Cancer Treatment With Anthracyclines in Childhood
Status: COMPLETED
Conditions: Myocardial Function|Echographic Parameters Obtaind by Speckle Tracking|Chilhood Cancers
Interventions: OTHER: Speckle Tracking Echocardiography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Pivotal Study to Evaluate the Bio-equivalence of the Tapentadol Extended-Release (ER) Tamper-resistant Formulation (TRF) Tablet to the Current Tapentadol ER Prolonged-release 2 (PR2) Tablet
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Tapentadol ER Tamper-resistant Formulation (TRF)|DRUG: Tapentadol ER Prolonged-Release 2 (PR2)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT