pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Embryo Transfer Outcomes After Vitrification With Slush Nitrogen Compared to Liquid Nitrogen
Status: COMPLETED
Conditions: Infertility
Interventions: OTHER: Vitrification via slush nitrogen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Nintendo WII and Exercises at Rehabilitation of Individuals With Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: OTHER: Exercises|OTHER: Nintendo Wii|OTHER: Exercises and Nintendo Wii
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Postpartum Pelvic Floor Workshop
Status: COMPLETED
Conditions: Pelvic Floor Disorders|Pelvic Floor; Incompetency|Pelvic Floor Muscle Weakness|Perineum; Injury
Interventions: BEHAVIORAL: Pelvic floor workshop
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Belzutifan (MK-6482) Hepatic Impairment Study (MK-6482-020)
Status: COMPLETED
Conditions: Moderate Hepatic Impairment
Interventions: DRUG: Belzutifan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: IGF-1/IGFBP3 Prevention of Retinopathy of Prematurity
Status: COMPLETED
Conditions: Retinopathy of Prematurity (ROP)
Interventions: DRUG: rhIGF-I/rhIGFBP-3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: To Assess the Efficacy of the Investigational Products Compared to Placebo in Participants With IPF
Status: ACTIVE_NOT_RECRUITING
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: DRUG: LTP001|DRUG: Placebo|DRUG: Standard of Care (SoC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety and Efficacy of Afamelanotide in Patients With Variegate Porphyria (VP)
Status: COMPLETED
Conditions: Variegate Porphyria
Interventions: DRUG: Afamelanotide 16 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Pelvic Belt and Kinesio Tape on Pain and Functional Mobility in Pregnancy-Related Pelvic Girdle Pain
Status: UNKNOWN
Conditions: Pelvic Girdle Pain
Interventions: OTHER: Kinesio tape (KT)|OTHER: Pelvic belt (PB)|OTHER: Educational program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy and Autologous Peripheral Stem Cell Transplant in Treating Patients With Stage III, Stage IV, or Recurrent Ovarian Epithelial Cancer, Primary Peritoneal Cancer, or Fallopian Tube Cancer
Status: COMPLETED
Conditions: Fallopian Tube Cancer|Ovarian Cancer|Peritoneal Cavity Cancer
Interventions: BIOLOGICAL: filgrastim|DRUG: cisplatin|DRUG: cyclophosphamide|DRUG: melphalan|DRUG: paclitaxel|DRUG: topotecan hydrochloride|GENETIC: TdT-mediated dUTP nick end labeling assay|GENETIC: gene expression analysis|OTHER: immunohistochemistry staining method|OTHER: pharmacological study|PROCEDURE: peripheral blood stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: The Influence of 3D Surgical Template on the Contour of Bone Augmentation, in Patient With Labial Alveolar Ridge Defect and Simultaneous Implantation
Status: ACTIVE_NOT_RECRUITING
Conditions: Bone Deformity
Interventions: PROCEDURE: 3D Surgical Template on the Contour of Bone Augmentation, in Patient With Labial Alveolar Ridge Defect and Simultaneous Implantation|PROCEDURE: conventional guided bone regeneration,in Patient With Labial Alveolar Ridge Defect and Simultaneous Implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MN-001 in Non-alcoholic Fatty Liver Disease, Type 2 Diabetes Mellitus, and Hypertriglyceridemia
Status: RECRUITING
Conditions: Diabetes Mellitus, Type 2|Hypertriglyceridemia|Non-Alcoholic Fatty Liver Disease
Interventions: DRUG: MN-001|DRUG: MN-001 placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of MEDI0382 in Combination With Dapagliflozin and Metformin in Overweight/Obese Participants With Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: MEDI0382|DRUG: Placebo|DRUG: Dapaglifozin|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of GnRH Agonist vs GnRH Antagonist on Oocyte Morphology in Polycystic Ovary Syndrome Patients During IVF/ICSI
Status: COMPLETED
Conditions: In Vitro Fertilization|Infertility|Intracytoplasmic Sperm Injection|Polycystic Ovary Syndrome
Interventions: DRUG: Triptorelin acetate|DRUG: Cetrorelix|DRUG: recombinant-FSH or recombinant-FSH + human Menopausal Gonadotropin|DRUG: Human Chorionic Gonadotropin (hCG)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Coenzyme Q10 for Gulf War Illness: A Replication Study
Status: NOT_YET_RECRUITING
Conditions: Gulf War Syndrome|Persian Gulf Syndrome|Mitochondrial Disorder, Respiratory Chain
Interventions: DRUG: PharmaNord Bio-Quinone Active CoQ10 Gold 100mg|DRUG: PharmaNord Placebo|DRUG: PharmaNord Bio-Quinone Active CoQ10 Gold 100mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Microbial Soy Milk Consumption, Inflammation and Renal Function Among Type 2 Diabetic Patients With Nephropathy
Status: COMPLETED
Conditions: Type II Diabetic Patients With Nephropathy
Interventions: DIETARY_SUPPLEMENT: probiotic soy milk
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Nab-paclitaxel Plus PD-1 Inhibitor Versus Nab-paclitaxel as Second-line Treatment in Advanced Gastric Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Gastric Cancer|GastroEsophageal Cancer
Interventions: DRUG: Albumin-bound Paclitaxel Plus SHR-1210 (PD-1 inhibitor)|DRUG: Albumin-bound Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Comparing Prevenar® to Pneumo 23 in Reducing Carriage in Children
Status: COMPLETED
Conditions: Vaccines, Pneumococcal|Vaccines, Pneumococcal Conjugate Vaccine
Interventions: BIOLOGICAL: pneumococcus conjugate vaccine 7 valent to reduce carriage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of Metformin With or Without Rapamycin as Maintenance Therapy After Induction Chemotherapy in Subjects With Pancreatic Cancer
Status: COMPLETED
Conditions: Metastatic Pancreatic Adenocarcinoma
Interventions: DRUG: metformin alone (Arm A)|DRUG: metformin (Arm B)|DRUG: rapamycin (Arm B)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Double Blind Crossover Study on the Effect of MPH on Decision-making Ability of Adults With BPD Compared to Adults With ADHD and Healthy Adults
Status: UNKNOWN
Conditions: Borderline Personality Disorder
Interventions: DRUG: methylphenidate
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of Venetoclax Plus Lenalidomide and Dexamethasone for the Treatment of Newly Diagnosed t(11;14)-Positive Multiple Myeloma in Subjects Who Are Ineligible for High-Dose Therapy
Status: WITHDRAWN
Conditions: Multiple Myeloma
Interventions: DRUG: venetoclax|DRUG: lenalidomide|DRUG: dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Relationship Between PFTs and Pdi in DMD
Status: WITHDRAWN
Conditions: Duchenne Muscular Dystrophy
Interventions: DIAGNOSTIC_TEST: Esophageal Balloon|DIAGNOSTIC_TEST: Gastric Balloon|DIAGNOSTIC_TEST: Nasal Pressure Transducer
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: AVJ-301 Clinical Trial: A Clinical Evaluation of AVJ-301 (Absorb™ BVS) in Japanese Population
Status: COMPLETED
Conditions: Coronary Artery Disease|Myocardial Ischemia
Interventions: DEVICE: XIENCE PRIME®/XIENCE Xpedition™|DEVICE: Absorb™ BVS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating Desvenlafaxine Succinate Sustained-Release (DVS SR) In The Treatment Of Peri- And Postmenopausal Women With Major Depressive Disorder (DVS 3364)
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: desvenlafaxine succinate sustained-release|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Physical Activity Intervention in African American Men After Radical Prostatectomy
Status: WITHDRAWN
Conditions: Prostatectomy|Prostate Cancer
Interventions: OTHER: Community Health Activities Model Program for Seniors (CHAMPS)|OTHER: Lifetime Total Physical Activity Questionnaire|OTHER: Expanded Prostate Cancer Index Composite (EPIC)|OTHER: International Physical Activity Prevalence Study Environmental Module|OTHER: Godin Leisure-Time Exercise Questionnaire (GLTEQ)|OTHER: Questionnaire regarding behavior/lifestyle changes since diagnosis|OTHER: 12 week Walking Program|OTHER: 12 week Resistance Training Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Impact of Simple Home-based Differential Learning on Oral Hygiene in Children.
Status: UNKNOWN
Conditions: Dental Caries|Gingival Diseases
Interventions: BEHAVIORAL: Differential learning|BEHAVIORAL: Usual toothbrushing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of CDX-585 in Patients With Advanced Malignancies
Status: RECRUITING
Conditions: Non-small Cell Lung Cancer|Gastric Cancer|Head and Neck Cancer|Ovarian Cancer|Primary Peritoneal Carcinoma|Fallopian Tube Cancer|Bladder Urothelial Carcinoma|Colorectal Cancer|Esophageal Cancer|Hepatic Cancer|Renal Cell Carcinoma|Cholangiocarcinoma|Pancreatic Cancer|Other Solid Tumors
Interventions: DRUG: CDX-585
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Repetitive Transcranial Magnetic Stimulation in Cancer Patients With Depression and Anxiety
Status: COMPLETED
Conditions: Cancer in Remission (Any Type or Stage)|Depression|Anxiety
Interventions: DEVICE: Repetitive Transcranial Magnetic Stimulation (rTMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cytotoxic T Cells to Treat Relapsed EBV-positive Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Hodgkin Disease|Non Hodgkin Lymphoma|Lymphoepithelioma|Severe Chronic Active EBV Infection Syndrome (SCAEBV)|Leiomyosarcoma
Interventions: DRUG: LMP1/2 CTLs (Group A)|DRUG: LMP1/2 CTLs (Group B)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High Dose Accelerated iTBS for Depression
Status: RECRUITING
Conditions: Major Depressive Disorder
Interventions: DEVICE: Active iTBS|DEVICE: Sham iTBS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess Long-Term Safety of the CyPass Micro-Stent in Patients Completing the COMPASS Trial
Status: COMPLETED
Conditions: Primary Open Angle Glaucoma (POAG)
Interventions: DEVICE: CyPass Micro-Stent|PROCEDURE: Cataract Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: GNR-084 Safety and Pharmacological Characteristics in Refractory or Relapse B-cell Precursor ALL
Status: RECRUITING
Conditions: B-precursor Acute Lymphoblastic Leukemia|ALL|GNR-084
Interventions: BIOLOGICAL: Cohort 1, GNR-084|BIOLOGICAL: Cohort 2, GNR-084|BIOLOGICAL: Cohort 3, GNR-084|BIOLOGICAL: Cohort 4, GNR-084|BIOLOGICAL: Cohort 5, GNR-084|BIOLOGICAL: Cohort 6, GNR-084
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I Study of BEBT-209 in Women With Advanced Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Breast Cancer
Interventions: DRUG: BEBT-209 capsules|DRUG: Letrozole tablets|DRUG: Fulvestrant
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Serial mpMRI (Multi Parametric Magnetic Resonance Imaging) Scanning in Prostate Cancer After Androgen Deprivation Therapy and RadioTherapy
Status: UNKNOWN
Conditions: Prostate Cancer
Interventions: DEVICE: mpMRI/VERDICT|RADIATION: External Beam Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Trial of Maintenance With Niraparib- Uterine Serous Carcinoma
Status: RECRUITING
Conditions: Endometrial Cancer|Papillary Serous Endometrial Carcinoma|Uterine Serous Carcinoma|Endometrial Carcinoma|Cancer of the Endometrium
Interventions: DRUG: Niraparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: VITAMIN E, C and ZINC IN PATIENTS WITH SKIN CANCER: INFLUENCE ON OXIDATIVE STRESS AND INFLAMMATORY STATE
Status: COMPLETED
Conditions: Skin Neoplasms
Interventions: DIETARY_SUPPLEMENT: Vitamin C, E and Zinc
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Safety Study of SGN-CD33A in Combination With Standard-of-care in Patients With AML
Status: COMPLETED
Conditions: Acute Myeloid Leukemia|Acute Myelogenous Leukemia
Interventions: DRUG: Standard dose cytarabine for induction|DRUG: SGN-CD33A|DRUG: Daunorubicin|DRUG: High dose cytarabine for consolidation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Heliox-Driven Racemic Epinephrine in Treatment of Bronchiolitis in Pediatric ED Patients
Status: COMPLETED
Conditions: Bronchiolitis
Interventions: DRUG: heliox|DRUG: oxygen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PiB PET Scanning in Speech and Language Based Dementias
Status: COMPLETED
Conditions: PPA|Primary Progressive Aphasia|Aphasia|Non-fluent Aphasia|Semantic Dementia|Apraxia of Speech|Primary Progressive Nonfluent Aphasia|Progressive Aphasia
Interventions: DRUG: C-11 PiB|DRUG: F-18 FDG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Liposomal Doxorubicin Plus Ifosfamide in Treating Patients With Advanced or Metastatic Soft Tissue Sarcoma
Status: COMPLETED
Conditions: Sarcoma
Interventions: DRUG: ifosfamide|DRUG: pegylated liposomal doxorubicin hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Antiperistaltic Effect and Safety of Glycopyrronium for Colonoscopic Polypectomy
Status: ENROLLING_BY_INVITATION
Conditions: Glycopyrrolate|Colonoscopy
Interventions: DRUG: Glycopyrrolate|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PEN Implementation Study
Status: COMPLETED
Conditions: Package of Essential Non-Communicable Diseases (PEN)|Peer Coaching|Clinical Audit|Mixed Method Implementation Study
Interventions: OTHER: Reinforcement of Peer coaching and clinical audit|OTHER: Continuation of usual practice without intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Efficacy and Safety of Gadobutrol 1.0 Molar (Gadovist) for Breast Magnetic Resonance Imaging (MRI)
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Gadobutrol (Gadavist, Gadovist, BAY86-4875)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of Post COVID-19 Mechanisms for Chronic Lung Sequelae
Status: RECRUITING
Conditions: COVID-19
Interventions: PROCEDURE: Bronchoscopies and Bronchoalveolar Lavages (BALs)|DIAGNOSTIC_TEST: Chest Tomography (CT)|DIAGNOSTIC_TEST: Electrocardiogram (ECG)|DIAGNOSTIC_TEST: Pulmonary function tests (PFTs)|DIAGNOSTIC_TEST: 6 minute walk test (6MWT)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Application of Indocyanine Green Angiography for Closed Operative Calcaneus Fractures
Status: TERMINATED
Conditions: Fractures, Comminuted|Surgical Wound Dehiscence|Necrosis
Interventions: DRUG: ICG (Indocyanine Green)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy of Andecaliximab (GS-5745) in Adults With Moderately to Severely Active Ulcerative Colitis
Status: TERMINATED
Conditions: Ulcerative Colitis
Interventions: BIOLOGICAL: Andecaliximab|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Evaluation of Inhaleen Inhalation in Hospitalized COVID-19 Patients
Status: COMPLETED
Conditions: Covid19
Interventions: DEVICE: Carragelose|DEVICE: NaCl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Inotuzumab Ozogamicin and Chemotherapy in Treating Patients With Recurrent or Refractory B-cell Acute Lymphoblastic Leukemia
Status: COMPLETED
Conditions: Recurrent B Acute Lymphoblastic Leukemia|Recurrent B Lymphoblastic Lymphoma|Refractory B Acute Lymphoblastic Leukemia|Refractory B Lymphoblastic Lymphoma
Interventions: DRUG: Etoposide|DRUG: Doxorubicin|DRUG: Vincristine|DRUG: Prednisone|DRUG: Cyclophosphamide|BIOLOGICAL: Inotuzumab Ozogamicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A 6 Week Trial to Study the Efficacy and Safety of a Starting Dose 0.25 mg Pramipexole (Mirapex) in Patients With RLS
Status: COMPLETED
Conditions: Restless Legs Syndrome
Interventions: DRUG: Pramipexole
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: GCC 1366: Anti-Proliferative Response to NeoAdjuvant AIs in Overweight and Obese Patients
Status: RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Anastrozole|DRUG: Letrozole
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Application of Group Interpersonal Psychotherapy (IPT-G) to Family Members Caring for Patients With Schizophrenia
Status: WITHDRAWN
Conditions: Interpersonal Psychotherapy|Family Caregivers
Interventions: BEHAVIORAL: Group Interpersonal Psychotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Clinical Characterization of an Investigational Frequent Replacement Daily Wear Silicone Hydrogel Sphere Contact Lens
Status: COMPLETED
Conditions: Refractive Errors
Interventions: DEVICE: LID021201 contact lenses|DEVICE: OPTI-FREE multipurpose solution
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Complete Health Improvement Program (CHIP) Risk Reduction/Claims Evaluation Project
Status: COMPLETED
Conditions: Cardiovascular Diseases|Diabetes Mellitus|Hypertension|Dyslipidemias|Overweight and Obesity
Interventions: BEHAVIORAL: The Complete Health Improvement Program
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Compression Anastomosis Using the Compression Anastomosis Ring (CAR™ 27)
Status: COMPLETED
Conditions: Colorectal Surgery
Interventions: DEVICE: Compression Anastomosis Ring: CAR™ 27
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: According CTC to Compare the Influences of Different Methods to Remove the PDAC
Status: UNKNOWN
Conditions: Carcinoma, Pancreatic Ductal|Circulating Tumor Cells
Interventions: PROCEDURE: routine surgery|PROCEDURE: no-touch surgery|PROCEDURE: laparoscopic surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Pancreatic Duct Stent Removal in Preventing Post-endoscopic Pancreatitis
Status: COMPLETED
Conditions: Acute Pancreatitis
Interventions: PROCEDURE: immediate stent removal|OTHER: Leaving the stent in place
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Local Anesthesia With Lidocaine or Articaine for Molars Affected by MIH
Status: COMPLETED
Conditions: Molar Incisor Hypomineralisation
Interventions: DRUG: Lidocaine 2%|DRUG: Articaine 4%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating SC291 in Subjects With r/r B-cell Malignancies (ARDENT)
Status: RECRUITING
Conditions: Non Hodgkin Lymphoma|Chronic Lymphocytic Leukemia
Interventions: DRUG: SC291
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasound-guided Bilateral Rectus Sheath Block for Robotic Single-port Gynecologic Surgery
Status: COMPLETED
Conditions: Gynecologic Disease
Interventions: PROCEDURE: Rectus sheath block|DRUG: Ropivacaine|OTHER: Bandage|DRUG: IV-PCA containing Fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Medical Device (MD) Derived Pharmacokinetic (PK) Parameters for Vancomycin (MD-PK)
Status: RECRUITING
Conditions: Infection, Bacterial|Antibiotic Side Effect|Antibiotic Resistant Infection|Sepsis|Septic Shock|Bacteremia|Critical Illness|Adult Children
Interventions: OTHER: Drug Infusion Pump Monitoring
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Preventing Postpartum Depression With Intranasal Oxytocin
Status: COMPLETED
Conditions: Depression, Postpartum|Anxiety
Interventions: DRUG: Oxytocin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: TFPB vs QLB III in Infra-umbilical Pediatric Surgeries
Status: RECRUITING
Conditions: Surgical Procedure, Unspecified
Interventions: OTHER: Transversalis Fascial Plane Block|OTHER: Quadratus Lumborum Plane Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Non-enteric Coated Enzymes Substitution on Pain in Patients With Chronic Pancreatitis
Status: COMPLETED
Conditions: Chronic Pancreatitis|Pain
Interventions: DRUG: Non-enteric coated pancreatic enzyme preparation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility of Virtual Reality Assistance in Prostate Biopsy Under Local Anesthesia.
Status: NOT_YET_RECRUITING
Conditions: Prostate Cancer
Interventions: DEVICE: Use of Virtual Reality Assistance during prostate biopsies
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Blinatumomab Bridging Therapy
Status: RECRUITING
Conditions: B-cell Acute Lymphoblastic Leukemia|Refractory B Acute Lymphoblastic Leukemia|Relapsed B-cell Acute Lymphoblastic Leukemia
Interventions: DRUG: Blinatumomab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Two Fluid Strategies for Prevention of Post-dural Puncture Headache
Status: COMPLETED
Conditions: Post-Dural Puncture Headache
Interventions: DRUG: Restrictive fluid therapy|DRUG: Liberal fluid therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of rhGH Replacement Therapy in Patients With Pseudohypoparathyroidism Type Ia (PHP Ia)
Status: UNKNOWN
Conditions: Pseudohypoparathyroidism|Growth Hormone Deficiency, Dwarfism
Interventions: DRUG: recombinant human somatotropin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Omega-3-fatty Acids on Blood Levels Omega-3 Fatty Acids in Patients With Age-related Macular Degeneration
Status: COMPLETED
Conditions: Macular Degeneration
Interventions: DIETARY_SUPPLEMENT: Omega-3 fatty acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endoscopic Mucosal Resection (EMR) for Diagnosis of Hirschsprung's Disease
Status: UNKNOWN
Conditions: Chronic Constipation|Hirschsprung's Disease
Interventions: PROCEDURE: Endoscopic Mucosal Resection (EMR)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Tailoring NEOadjuvant Therapy in Hormone Receptor Positive, HER2 Negative, Luminal Breast Cancer.
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Neoplasms
Interventions: DRUG: Letrozole|DRUG: Chemotherapy|DRUG: Ribociclib plus letrozole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pelvic Organ Prolapse Repair Plus Mini-Sling Versus Pelvic Organ Prolapse Repair Alone
Status: COMPLETED
Conditions: Pelvic Organ Prolapse|Urinary Incontinence
Interventions: PROCEDURE: POP repair plus mini-sling|PROCEDURE: POP repair
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: AVTX-801 D-galactose Supplementation in SLC35A2-CDG
Status: NOT_YET_RECRUITING
Conditions: SLC35A2-CDG - Solute Carrier Family 35 Member A2 Congenital Disorder of Glycosylation
Interventions: DRUG: AVTX-801|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Randomized-controlled Trial of Integrated Palliative and Nephrology Care Versus Usual Nephrology Care.
Status: COMPLETED
Conditions: Chronic Kidney Diseases
Interventions: OTHER: Integrated ambulatory palliative and nephrology care|OTHER: Standard nephrology care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Home-based Bimodal Lifestyle Intervention in Patients With Liver Cirrhosis Awaiting Orthotopic Liver Transplantation
Status: NOT_YET_RECRUITING
Conditions: Liver Cirrhosis|Liver Transplant; Complications|Physical Inactivity
Interventions: OTHER: Bimodal lifestyle program
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Outcome of Patients With Acute Myeloblastic Leukemia and Myelodysplastic Syndrome Receiving Iron Chelation Therapy After Allogeneic Hematopoietic Stem Cell Transplantation
Status: UNKNOWN
Conditions: Myeloid Leukemia|Myelodysplastic Syndromes
Interventions: DRUG: EXJADE
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Ciprofloxacin/Celecoxib Combination in Patients With ALS
Status: COMPLETED
Conditions: ALS (Amyotrophic Lateral Sclerosis)
Interventions: DRUG: Fixed dose combination Ciprofloxacin/Celecoxib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Short-term Results After Minimally Invasive Chevron Osteotomy for Hallux Valgus Correction
Status: COMPLETED
Conditions: Hallux Valgus|Minimally Invasive Surgical Procedures
Interventions: PROCEDURE: open distal chevron osteotomy|PROCEDURE: minimally invasive distal chevron osteotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impacts of Durian Consumption on Human Microbiome and Metabolome in Healthy Staff Volunteers
Status: RECRUITING
Conditions: Diet, Food and Nutrition
Interventions: OTHER: Two-sequence of durian pulp doses (100 g and 200 g)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Laparoscopic Guided Peri-wound Transversus Abdominis Plane Block With Bupivacaine Versus Local Wound Infiltration on Post-op Opioid Use in Laparoscopic Sleeve Gastrectomy
Status: RECRUITING
Conditions: Morbid Obesity|Laparoscopic Sleeve Gastrectomy|Transversus Abdominis Plane Block|Local Wound Infiltration|Bupivacine|Opioid Use
Interventions: PROCEDURE: peri-wound Transversus Abdominis Plane Block|PROCEDURE: Local wound infiltration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Efficacy of Vactosertib and Imatinib in Patients With Advanced Desmoid Tumor
Status: COMPLETED
Conditions: Desmoid Tumor
Interventions: DRUG: vactosertib/imatinib combination
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Daily vs. Every Other Day Oral Iron Supplementation in Patients With Absolute Iron Deficiency Anemia
Status: COMPLETED
Conditions: Anemia|Iron Deficiency Anemia
Interventions: DRUG: Ferrous Sulfate 300Mg Tablet|DRUG: Vitamin C 500Mg tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Intradermal Quadrivalent Influenza Vaccine in Adults Aged 18 Through 64 Years
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Influenza Virus Vaccine USP Quadrivalent, (Zonal Purified Subvirion) 2012 2013 Formulation|BIOLOGICAL: Influenza Virus Vaccine USP Trivalent Types A and B (Zonal Purified Subvirion) Fluzone® Intradermal|BIOLOGICAL: Influenza Virus Vaccine USP Trivalent Types A and B (Zonal Purified Subvirion) Fluzone Intradermal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Anti-TGF-beta Therapy in Patients With Myelofibrosis
Status: TERMINATED
Conditions: Myelofibrosis|Primary Myelofibrosis|Polycythemia Vera, Post-Polycythemic Myelofibrosis Phase|Post-essential Thrombocythemia Related Myelofibrosis
Interventions: BIOLOGICAL: monoclonal antibody to TGF-beta
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Metolazone As Early Add On Therapy For Acute Decompensated Heart Failure (MELT-HF)--A Single Center Pilot Study.
Status: TERMINATED
Conditions: Acute Decompensated Heart Failure
Interventions: DRUG: Experimental: Placebo|DRUG: Experimental: Metolazone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of 25mg Versus 5 mg Lenalidomide as Maintenance Therapy in Patients With Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Lenalidomide|DRUG: Lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Dorso-lateral Prefrontal Cortex Stimulation by tDCS in Motor Conversion Disorder Patients
Status: RECRUITING
Conditions: Conversion Disorder
Interventions: DEVICE: Neurostimulation with non-implanted electrodes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pentoxifylline as an Adjunct to Citalopram in Adult Patients With Major Depressive Disorder
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: Citalopram (tablet) 20 mg + Pentoxifylline (tablet) 400Mg|DRUG: Citalopram (tablet) 20 mg + Placebo (tablet)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Retention and Duration of Activity of SPL7013 (VivaGel®) After Vaginal Dosing.
Status: COMPLETED
Conditions: HIV Infections|HSV-2 Genital Herpes
Interventions: DRUG: 3% SPL7013 Gel (VivaGel)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Azithromycin in MSAF Cases to Improve Maternal and Neonatal Outcomes
Status: COMPLETED
Conditions: Meconium Stained|Azithromycin|Postpartum Endometritis
Interventions: DRUG: Azithromycin capsule (Zithromax, Pfizer) (250 mg)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Spinal Cord Stimulation and Training
Status: RECRUITING
Conditions: Spinal Cord Injuries
Interventions: OTHER: Electrophysiology assessment - corticospinal tract|OTHER: Electrophysiology assessment - reticulospinal tract|OTHER: Electrophysiology assessment - spinal motoneuron|OTHER: Activity-based training|OTHER: Transcutaneous spinal cord stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Adjuvant Trastuzumab Deruxtecan (Enhertu) & Nivolumab For Patients Who Are Disease Free After Completion of Trimodality Treatment For HER-2+ Cancers of Esophagus & Gastroesophageal Junction
Status: RECRUITING
Conditions: Esophageal Adenocarcinoma|Esophageal Cancer|HER-2 Protein Overexpression|Gastroesophageal-junction Cancer
Interventions: DRUG: Nivolumab|DRUG: Trastuzumab deruxtecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Probiotics Effect on Glucose and Lipid Metabolism and Gut Microbiota in Patients With Obesity
Status: UNKNOWN
Conditions: Obesity
Interventions: DIETARY_SUPPLEMENT: Probiotics|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: TQLB for Postoperative Pain After Laparoscopic Partial Nephrectomy
Status: COMPLETED
Conditions: Laparoscopic Renal Surgery|Pain Management|Nerve Block
Interventions: PROCEDURE: single-injection TQLB(transmuscular quadratus lumborum block)|DRUG: Morphine given as IPCA(intravenous patient controlled analgesia)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Ph I Study of Alvocidib and Cytarabine/Daunorubicin (7+3) in Patients With Newly Diagnosed Acute Myeloid Leukemia (AML).
Status: COMPLETED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Alvocidib|DRUG: Cytarabine|DRUG: Daunorubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Role of a Combination of Nutraceuticals (Ritmonutra) on Benign Supraventricular and Ventricular Arrhythmias
Status: COMPLETED
Conditions: Ventricular and Atrial Extrasytoles
Interventions: DIETARY_SUPPLEMENT: Ritmonutra|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Stimulant Overdose in the Medicaid Population: Who is at Risk, and When Are They at Risk
Status: ACTIVE_NOT_RECRUITING
Conditions: Stimulant Overdose
Interventions: OTHER: Aim 1 (case-cohort study)|OTHER: Aim 2 (case-crossover study)|OTHER: Aim 3 (cohort study)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety, Tolerability and Pharmacokinetics of Oral Tablet of Irinotecan in Adult Patients With Solid Tumors
Status: COMPLETED
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: Irinotecan|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Aggregate Metabolic Phenotypes for (Poly)Phenols: Development of an Oral (Poly)Phenol Challenge Test (OPCT)
Status: COMPLETED
Conditions: Individual Variability in (Poly)Phenol Metabolism|Cardiometabolic Health
Interventions: DIETARY_SUPPLEMENT: Oral (poly)phenol challenge test (OPCT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Using Pneumococcal Vaccines in Combination for Maximum Protection From Ear and Lung Infections in First 3 Years of Life
Status: COMPLETED
Conditions: Otitis Media|Febrile Illness|Cough|Lower Respiratory Tract Infection|Upper Respiratory Tract Infection
Interventions: BIOLOGICAL: Prevenar13|BIOLOGICAL: Synflorix
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluate Safety and Efficacy of Rifamycin SV MMX in the Treatment of Traveler's Diarrhea in Children Age 6 to 11 Years
Status: NOT_YET_RECRUITING
Conditions: Traveler's Diarrhea
Interventions: DRUG: Rifamycin SV-MMX|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Sulfasalazine for the Treatment of Primary Sclerosing Cholangitis
Status: RECRUITING
Conditions: Primary Sclerosing Cholangitis
Interventions: DRUG: Sulfasalazine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: UCDCC#271: Phase I/II Trial of Epacadostat, Intralesional SD101, Radiotherapy in Patients With Lymphoma
Status: COMPLETED
Conditions: Advanced Solid Tumors|Lymphoma
Interventions: DRUG: epacadostat|DRUG: SD-101|RADIATION: Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Mirikizumab in Participants With Plaque Psoriasis
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: Drug Cocktail|DRUG: Mirikizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study to Evaluate the Safety and Efficacy of XAV-19 in Patients With COVID-19 Induced Moderate Pneumonia
Status: COMPLETED
Conditions: SARS Virus
Interventions: DRUG: XAV-19|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Eradications Rates of Sequential Therapy Versus Concomitant Therapy
Status: UNKNOWN
Conditions: Helicobacter Pylori Infection
Interventions: DRUG: Sequential therapy 10 days|DRUG: Sequential therapy 14 days|DRUG: Concomitant therapy 10 days|DRUG: Concomitant therapy 14 days
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RCE With FMT in the Treatment of Childhood Constipation
Status: COMPLETED
Conditions: Fecal Microbiota Transplantation|Constipation - Functional
Interventions: DRUG: Fecal supernatant|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Broader Implementation of a Successful Dual-Generation Intervention in Partnership With Head Start of Lane County
Status: COMPLETED
Conditions: School Readiness
Interventions: BEHAVIORAL: Creating Connections: Strong Families, Strong Brains
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of PLX5622 in Healthy Adult Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: PLX5622|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase III Clinical Trial of Fentanyl Transdermal Matrix Patch, in the Management of Chronic Intractable Pain- Assessment of Effectiveness, Safety and Pharmacokinetics
Status: COMPLETED
Conditions: Pain, Intractable
Interventions: DRUG: fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Telaprevir (VX-950), Pegasys and Copegus in Hepatitis C (PROVE3)
Status: COMPLETED
Conditions: Hepatitis C
Interventions: DRUG: Telaprevir|DRUG: Ribavirin|DRUG: Pegylated Interferon Alfa 2a|DRUG: Matching Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prevalence of Obstructive Sleep Apnea (OSA) in Patients With Lymphedema, Admitted for Intensive Decongestive Physiotherapy
Status: UNKNOWN
Conditions: Lymphedema|Obstructive Sleep Apnea Syndrome
Interventions: OTHER: Intensive decongestive physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Aripiprazole and Topiramate on Free-Choice Alcohol Use
Status: COMPLETED
Conditions: Alcohol Dependence
Interventions: DRUG: Double Placebo|DRUG: Aripiprazole 15, placebo|DRUG: Aripiprazole 7.5, Placebo|DRUG: Topiramate 100, Placebo|DRUG: Topiramate 200, Placebo|DRUG: Topiramate 100, Aripiprazole 15|DRUG: Topiramate 100, Aripiprazole 7.5|DRUG: Topiramate 100, Aripiprazole 15mg|DRUG: Topiramate 200, Aripiprazole 7.5mg|DRUG: Topiramate 200, Aripiprazole 15
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Levalbuterol Compared to Albuterol Regarding Cardiac Side Effects and Potassium Lowering Effects.
Status: UNKNOWN
Conditions: Hyperkalemia
Interventions: DRUG: Levalbuterol|DRUG: Albuterol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Rituximab, Lenalidomide, Acalabrutinib, Tafasitamab Alone and With Combination Chemotherapy for the Treatment of Newly Diagnosed Non-germinal Center Diffuse Large B-Cell Lymphoma, Smart Stop Study
Status: RECRUITING
Conditions: Diffuse Large B-Cell Lymphoma
Interventions: DRUG: Acalabrutinib|DRUG: Cyclophosphamide|DRUG: Doxorubicin Hydrochloride|DRUG: Lenalidomide|DRUG: Prednisone|BIOLOGICAL: Rituximab|BIOLOGICAL: Tafasitamab|DRUG: Vincristine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Investigate Compliance With the Oral Contraceptive SH T00186D in a Flexible Extended Regimen Supported by a Dispenser With a Reminder Function
Status: COMPLETED
Conditions: Contraception
Interventions: DRUG: BAY86-5300|DRUG: BAY86-5300
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT