pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: SpyGlass in Preoperative Diagnostics of Presumed Main Duct IPMNs: Efficacy and Novel Insights on Complications
Status: COMPLETED
Conditions: Intraductal Papillary Mucinous Neoplasm
Interventions: PROCEDURE: SpyGlass pancreatoscopy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Intraoperative Neuromonitoring Recording With a Novel SCS Paddle: Phase II
Status: COMPLETED
Conditions: Chronic Pain|Neuropathic Pain|Failed Back Surgery Syndrome|Complex Regional Pain Syndromes
Interventions: DEVICE: HD Study Electrode
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Decitabine Plus mBU/CY Preconditioning for Relapse/Refractory Acute Leukemia
Status: UNKNOWN
Conditions: Stem Cell Transplant Complications|Relapse Leukemia|Refractory Leukemia
Interventions: DRUG: Decitabine|DRUG: mBU/CY and ATG|DRUG: mBU/CY
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Changing Diet on Fasting and Post Fat Load Lipoproteins
Status: COMPLETED
Conditions: Hypertriglyceridemia|Diabetes Mellitus
Interventions: OTHER: Low Fat/High Carbohydrate|OTHER: High Monounsaturated Fat/Low Carbohydrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of Karydakis and Limberg Flap Treatment of Pilonidal Sinus in Adolescent. a Prospective, Randomised Study
Status: UNKNOWN
Conditions: Pilonidal Sinus|Postoperative Complications
Interventions: PROCEDURE: pilonidal sinus excision
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: New Dermal Filler for Lip Augmentation
Status: COMPLETED
Conditions: Lip Augmentation
Interventions: DEVICE: New Dermal Filler|DEVICE: Device: FDA Approved Dermal Filler
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Synaptic Density, Tau and Multiparametric PET-MR in Brain Trauma, Stroke and Mild Cognitive or Behavioral Impairment.
Status: ENROLLING_BY_INVITATION
Conditions: Neuro-Degenerative Disease
Interventions: OTHER: PET-MR imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Randomized, Phase I, Cross-Over Study to Assess the Relative Bioavailability of Single-Dose Cobimetinib (GDC-0973) in Tablet vs. Capsule Formulation
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: cobimetinib|DRUG: cobimetinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Infusion of Donor Lymphocytes Transduced With the Suicide Gene HSV TK in Patients With Haematological Malignancies
Status: COMPLETED
Conditions: Hematological Malignancies
Interventions: GENETIC: HSV-TK
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Poul Gjessing Versus T Loops for Orthodontic Maxillary Canine Retraction
Status: ACTIVE_NOT_RECRUITING
Conditions: Canine Retraction
Interventions: DEVICE: Poul Gjessing|DEVICE: T loops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Application of Augmented Reality Neuronavigation in Transnasal Endoscopic Skull Base Surgery
Status: NOT_YET_RECRUITING
Conditions: Pituitary Neoplasms
Interventions: DEVICE: Performing endoscopic transnasal skull base surgery with AR-integrated endoscope
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Assessing the Impact of Self-directed Care, Within a Medicaid-funded Environment,on Participation and Community Living
Status: COMPLETED
Conditions: Major Depression|Bipolar Disorder|Schizophrenia
Interventions: BEHAVIORAL: self-directed care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Temozolomide for Injection Combined With Epirubicin in First-line Treatment of Leiomyosarcoma
Status: UNKNOWN
Conditions: Leiomyosarcoma
Interventions: DRUG: Temozolomide for injection combined with epirubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Determine if a New Malaria Vaccine is Safe and Induces Immunity Among Kenyan Adults, Young Children and Infants
Status: COMPLETED
Conditions: Malaria,Falciparum
Interventions: BIOLOGICAL: R21 in Matrix- M adjuvant vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Patient Portal Tool, E-assist, for Supporting CRC Screening
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: BEHAVIORAL: e-assist: Colon Health|BEHAVIORAL: Healthwise Educational Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Trial Evaluating the Safety and Pharmacokinetics of MFGR1877S in Patients With Advanced Solid Tumors
Status: COMPLETED
Conditions: Solid Tumor
Interventions: DRUG: MFGR1877S
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prediction of the Efficacy of Activated Recombinant Human Factor VII in Adult Congenital Haemophilia A or B Patients With Inhibitors by Use of Thromboelastography
Status: COMPLETED
Conditions: Congenital Bleeding Disorder|Haemophilia A With Inhibitors|Haemophilia B With Inhibitors
Interventions: DRUG: eptacog alfa (activated)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Mechanisms of Human Cutaneous Microcirculation in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DEVICE: pressure strain system, iontophoresis|DRUG: scopolamin|DRUG: emla|DRUG: capsaicin|DRUG: aspirin|DRUG: clopidogrel|DRUG: celecoxib|DRUG: indomethacin|DRUG: acetylcholine|DRUG: sodium nitroprusside|DRUG: brethyllium|DEVICE: general and local heating
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Tofacitinib and Methotrexate in the Maintained Treatment of GPA
Status: UNKNOWN
Conditions: Granulomatosis With Polyangiitis
Interventions: DRUG: Tofacitinib|DRUG: Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial to Evaluate the Safety and Efficacy of SM-020 Gel 1.0% in Subjects With Seborrheic Keratosis
Status: RECRUITING
Conditions: Seborrheic Keratosis
Interventions: DRUG: SM-020 gel 1.0%|DRUG: Vehicle gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Diclofenac 1.16% Gel in Subjects With Acute Neck Pain
Status: COMPLETED
Conditions: Neck Pain
Interventions: DRUG: Diclofenac diethylamine 1.16% gel|DRUG: Placebo gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: NO Measurements in Screening for Asthma and OSA, in Patients With Severe Snoring
Status: COMPLETED
Conditions: Snoring|Obstructive Sleep Apnea|Asthma|Airway Disease|Inflammatory Disease|Concomitant Disease
Interventions: DIAGNOSTIC_TEST: Fractioned Exhaled Nitrogen Oxide measurements
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Incidence of MRI Sacro-Iliac Joint Anomalies in Young Women
Status: COMPLETED
Conditions: Women (Between 18 to 50 Years Old)|Sacro-iliac Joints|Inflammatory Lesions|Structural Lesions|Axial Spondyloarthritis
Interventions: OTHER: Standard care
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: HSAT for OSA Management in Children
Status: RECRUITING
Conditions: Sleep Apnea, Obstructive|Sleep Disorder|Sleep Apnea Syndromes|Sleep Disturbance
Interventions: DIAGNOSTIC_TEST: Home sleep apnea test|DIAGNOSTIC_TEST: PSG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy of Electroencephalography (EEG) Neurofeedback (NF) for the Treatment of Anxiety Disorder
Status: UNKNOWN
Conditions: Anxiety Disorder|Healthy
Interventions: DRUG: SSRI or SNRI or benzodiazepines or tricyclic antidepressants or other antidepressants or antipsychotics or other sedative-hypnotics|DEVICE: Neurofeedback system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Epoetin Alfa Deep Tank in Treatment of Anemia in Patients With Chronic Kidney Disease Receiving Hemodialysis
Status: COMPLETED
Conditions: Nephrology
Interventions: DRUG: Epoetin alfa RB|DRUG: Epoetin alfa DT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Open vs Laparoscopic Pyloromyotomy for Pyloric Stenosis
Status: TERMINATED
Conditions: Pyloric Stenosis
Interventions: PROCEDURE: laparoscopy pyloromyotomy|PROCEDURE: open pyloromytomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Restoring Arm and Hand Function With Non-invasive Spinal Stimulation
Status: COMPLETED
Conditions: Paralysis|Spinal Cord Injury
Interventions: DEVICE: Transcutaneous Electrical Spinal Cord Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Postoperative Recovery Quality According to Preoperative Fasting Time in Pediatric Patients Undergoing Nuss Operation
Status: UNKNOWN
Conditions: Pectus Excavatum
Interventions: DIETARY_SUPPLEMENT: New Care No Nil Per Os
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Tremella Fuciformis on Improvement in Cognitive-Bio-Markers of Cognitive Functions
Status: COMPLETED
Conditions: Healthy Adults With Subjective Memory Complaints
Interventions: DIETARY_SUPPLEMENT: TF 600mg|DIETARY_SUPPLEMENT: TF 1200mg|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rhythmic Auditory Stimulation Optimalization for Gait Improvement in Parkinson's Disease - BeatPark Study
Status: UNKNOWN
Conditions: Parkinson's Disease
Interventions: BEHAVIORAL: Neuropsychological evaluation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Cell-free Fetal DNA Concentration in Cases of Abnormal Placental Invasion .
Status: UNKNOWN
Conditions: Placenta Accreta|Placenta Percreta|Placenta Increta|Placenta Previa
Interventions: DIAGNOSTIC_TEST: Maternal plasma cell free fetal DNA levels
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical Study on BIFICO Accelerating Postoperative Liver Function Recovery in Patients With Hepatocellular Carcinoma
Status: COMPLETED
Conditions: Gut Microbiota|Hepatocellular Carcinoma|Bifidobacterium
Interventions: DRUG: BIFICO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TPF Induction Chemotherapy vs PF Adjuvant Chemotherapy Combined With Concurrent Chemoradiotherapy in the Treatment of Locally Advanced NPC
Status: UNKNOWN
Conditions: Locally Advanced Nasopharyngeal Carcinoma
Interventions: DRUG: TPF+CCRT|DRUG: CCRT+PF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of tACS vs tDCS in Schizophrenia
Status: RECRUITING
Conditions: Schizophrenia
Interventions: DEVICE: transcranial Alternating current stimulation (tACS)|DEVICE: transcranial Direct current stimulation (tDCS)|DEVICE: Sham controlled
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Native Outflow Tract Transcatheter Pulmonary Valve (TPV)
Status: COMPLETED
Conditions: Congenital Heart Disease|Tetralogy of Fallot
Interventions: DEVICE: Native Outflow Tract TPV
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: An Open Label, Exploratory Study to Investigate the Treatment Effect of Glatiramer Acetate on Girls Woth Rett Syndrome
Status: UNKNOWN
Conditions: Rett Syndrome
Interventions: DRUG: Glatiramer Acetate (Copaxone®)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transcutaneous Diaphragm Electrical Stimulation in Critically Ill Patients
Status: COMPLETED
Conditions: Critical Illness|Mechanical Ventilation|Intensive Care Unit
Interventions: DEVICE: Sham electrical stimulation|DEVICE: Transcutaneous diaphragm electrical stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Adjusting the Dose of Therapeutic Exercise to Prevent Neurotoxicity Due to Anticancer Treatment (ATENTO)
Status: RECRUITING
Conditions: Breast Neoplasm
Interventions: OTHER: ATENTO-B|OTHER: ATENTO-T
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lowering the Impact of Food Insecurity in African American Adults With Type 2 Diabetes Mellitus (LIFT-DM)
Status: ACTIVE_NOT_RECRUITING
Conditions: Type 2 Diabetes
Interventions: BEHAVIORAL: Diabetes Education Plus Monthly Food Vouchers|BEHAVIORAL: Diabetes Education Plus Combination of Monthly Food Vouchers and Stock Boxes|BEHAVIORAL: Diabetes Education Only|BEHAVIORAL: Diabetes Education Plus Monthly Stock Boxes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Combination Study of BMS-754807 and Erbitux® in Subjects With Advanced or Metastatic Solid Tumors
Status: TERMINATED
Conditions: Colorectal Cancer|Head and Neck Cancer|Neoplasm Metastasis
Interventions: DRUG: BMS-754807|DRUG: cetuximab (Erbitux®)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study on Cemented Versus Non-cemented Hemiarthroplasty in Elderly With Hip Fractures
Status: COMPLETED
Conditions: Hip Fracture
Interventions: PROCEDURE: cemented Landos prosthesis vs. uncemented Landos prosthesis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Supplemented Very Low Protein Diet and the Progression of Chronic Kidney Disease
Status: COMPLETED
Conditions: Chronic Kidney Disease
Interventions: BEHAVIORAL: Conventional low protein diet|DIETARY_SUPPLEMENT: Very low protein diet supplemented with Ketosteril
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Early Rest on Recovery From Pediatric Concussion
Status: COMPLETED
Conditions: Mild Traumatic Brain Injury|Concussion|Post-concussive Syndrome
Interventions: BEHAVIORAL: Mandated Rest, Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Apo805K1 in Subjects With Moderate to Severe Chronic Plaque Psoriasis
Status: COMPLETED
Conditions: Plaque Psoriasis
Interventions: DRUG: Apo805K1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Peri-operative SLOG for Localized Pancreatic Cancer
Status: RECRUITING
Conditions: Pancreatic Ductal Adenocarcinoma|Pancreas Cancer
Interventions: DRUG: S-1, leucovorin, oxaliplatin and gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: IT-system Development for Reaching Cervix Cancer Screening Non-attenders
Status: UNKNOWN
Conditions: Human Papillomavirus DNA Tests|Cervical Cancer
Interventions: DEVICE: Cobas PCR Female swab sample Packet|OTHER: Routine practice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Optimal Duration of Dual Antiplatelet Therapy After Stent-assisted Coiling
Status: RECRUITING
Conditions: Aneurysm Cerebral|Endovascular Procedures
Interventions: DRUG: Aspirin 100mg|DRUG: Clopidogrel 75mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of an Exercise and Lifestyle Education Program for People With Diabetes and Prediabetes
Status: ACTIVE_NOT_RECRUITING
Conditions: Diabetes Mellitus|Prediabetes
Interventions: BEHAVIORAL: Exercise Program|BEHAVIORAL: Lifestyle Education Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety of INCA33890 in Participants With Advanced or Metastatic Solid Tumors
Status: RECRUITING
Conditions: Solid Tumors|Advanced Solid Tumors|Metastatic Solid Tumors
Interventions: DRUG: INCA33890
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy Combined With Pembrolizumab in Treating Patients With Thymoma and Thymic Carcinoma
Status: UNKNOWN
Conditions: Thymoma and Thymic Carcinoma
Interventions: DRUG: Chemotherapy+Pembrolizumab.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Contrast Media Reduction and Removal in Patients With Chronic Kidney Disease (CKD) (PRESERV)
Status: TERMINATED
Conditions: Radiographic Contrast Agent Nephropathy
Interventions: DEVICE: CINCOR™ System and contrast conservation unit (CCS-1)|OTHER: Standard of Care plus peri-procedural hydration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Intensive Therapy Associated With CSII on β-cell Function With Newly Diagnosed Type 2 Diabetes
Status: SUSPENDED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: CSII,ALA,MET,RSG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pericardial Fluid Analysis in Recurrent Pericarditis
Status: NOT_YET_RECRUITING
Conditions: Acute Pericarditis|Pericardial Effusion|Pericardial Disease|Pericardial Fluid Exudate|Autoinflammatory Disorders|Autoinflammatory Disease
Interventions: DIAGNOSTIC_TEST: Pericardiocentesis|DIAGNOSTIC_TEST: Pericardiotomy|DIAGNOSTIC_TEST: Cytofluorometry and Gene expression analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Postoperative Nausea and Vomiting in Laparoscopic Abdominal Surgery
Status: NOT_YET_RECRUITING
Conditions: Postoperative Nausea|Vomiting
Interventions: DRUG: Aprepitant|DRUG: Granisetron
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of the Efficacy and Safety of VX-150 in Subjects With Osteoarthritis of the Knee
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DRUG: VX-150|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Efficacy of Dienogest in the Treatment of Uterine Leiomyomas When Compared to Desogestrel and Goserelin
Status: TERMINATED
Conditions: Uterine Leiomyoma
Interventions: DRUG: Dienogest|DRUG: Goserelin|DRUG: Desogestrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Cadonilimab（AK104） Plus Lenvatinib in Previous Immunotherapy Treated Advanced/Metastatic Clear Cell Renal Cell Carcinoma
Status: RECRUITING
Conditions: Clear Cell Renal Cell Carcinoma、Resistance to Immunotherapy
Interventions: DRUG: AK104（anti-PD-1/CTLA-4 bi-specific antibody ，intravenously）,lenvatinib（ targeted VEGFR 1-3、FGFR、PDGFRα， small molecule TKI，orally
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Interpretation of Health News Items Reporting Results of Randomized Controlled Trials With or Without Spin by French-speaking Patients
Status: WITHDRAWN
Conditions: The Study Focus on no Specific Condition
Interventions: OTHER: News items with spin|OTHER: News items without spin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Assessment of Gastric pH Changes Induced by Ascorbic Acid Tablets
Status: ACTIVE_NOT_RECRUITING
Conditions: Hypochlorhydria
Interventions: DRUG: Omeprazole 20mg|DIETARY_SUPPLEMENT: Vitamin C
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Needlescopic vs. Conventional Laparoscopic Adrenalectomy for Tumor Less Than 4 cm
Status: NOT_YET_RECRUITING
Conditions: Post Operative Pain, Acute
Interventions: DEVICE: Needlescopic laparoscopic adrenalectomy|DEVICE: conventional laparoscopic adrenalectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: TAA06 Injection in the Treatment of Patients With B7-H3-positive Relapsed/ Refractory Neuroblastoma
Status: RECRUITING
Conditions: B7-H3-positive Relapsed/ Refractory Neuroblastoma
Interventions: BIOLOGICAL: T cell injection targeting B7-H3 chimeric antigen receptor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Psychological Treatment to Support the Consequences of Cognitive Impairment
Status: RECRUITING
Conditions: Cognitive Impairment|Psychological|Psychotherapy|Health Behavior
Interventions: BEHAVIORAL: Psychological treatment|BEHAVIORAL: Cognitive training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Learn About the Safety and Immune Response of a New Pneumococcal Vaccine in Adults
Status: ACTIVE_NOT_RECRUITING
Conditions: Pneumococcal Disease
Interventions: BIOLOGICAL: Multivalent Pneumococcal Vaccine - Formulation 1|BIOLOGICAL: Multivalent Pneumococcal Vaccine - Formulation 2|BIOLOGICAL: 20-valent pneumococcal conjugate vaccine (20vPnC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Assessment of the Rate of Oseointegration Surrounding Nano-coated Orthodontic Titanium Miniscrew
Status: COMPLETED
Conditions: Health Care Utilization|Diet, Healthy|Frey Syndrome
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of mTOR Inhibition and Other Metabolism Modulating Interventions on the Elderly
Status: COMPLETED
Conditions: Aging
Interventions: DRUG: Rapamycin|DRUG: Placebo|DRUG: Rapamycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: S9809, Ciprofloxacin Compared With Cephalexin in Treating Patients With Bladder Cancer
Status: TERMINATED
Conditions: Bladder Cancer
Interventions: DRUG: cephalexin|PROCEDURE: surgical procedure|DRUG: Ciprofloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mitochondrial Remodeling After Exercise
Status: COMPLETED
Conditions: Overweight and Obesity|Insulin Resistance|Metabolic Disease|Mitochondrial Metabolism|Sedentary Lifestyle
Interventions: BEHAVIORAL: Short-term Exercise Training
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Calcium, Probiotics and Acute Diarrheal Disease Among Indonesian Children
Status: COMPLETED
Conditions: Healthy|Diarrhea
Interventions: DIETARY_SUPPLEMENT: low calcium milk of 180 ml|DIETARY_SUPPLEMENT: regular milk of 180 ml|DIETARY_SUPPLEMENT: regular milk of 180 ml + probiotics|DIETARY_SUPPLEMENT: regular milk of 180 ml + probiotics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficiency Study to Investigate Blonanserin in Treatment of Schizophrenia When Compared With Risperidone
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Blonanserin|DRUG: Risperidone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mechanisms of Chiropractic Spinal Manipulation for Chronic Low Back Pain
Status: COMPLETED
Conditions: Chronic Low-back Pain
Interventions: OTHER: Spinal Manipulation|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Using Combined Instantaneous and Multidimensional Feedback to Support a Change in Physical Activity Behaviour
Status: COMPLETED
Conditions: Motor Activity|Cardiovascular Diseases|Type 2 Diabetes Mellitus
Interventions: BEHAVIORAL: Instant + Multidimensional Physical Activity Feedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Assessing Manual Acupuncture's Impact on Mucositis From Nasopharynx Cancer Radiotherapy: A Visual Analogue Scale (VAS) and Quality of Life Study
Status: NOT_YET_RECRUITING
Conditions: Cancer|Nasopharyngeal Carcinoma|Mucositis
Interventions: PROCEDURE: Verum Acupuncture|PROCEDURE: Sham Acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Extended Use of Cannabidiol for the Prevention of Graft-versus-host-disease
Status: UNKNOWN
Conditions: Graft vs Host Disease
Interventions: DRUG: Cannabidiol|DRUG: cyclosporine|DRUG: Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Phase I Clinical Study of Chondroitin Sulfate for Treatment of NEC
Status: NOT_YET_RECRUITING
Conditions: Necrotizing Enterocolitis|Intestinal Ischemia
Interventions: DRUG: Chondroitin sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Local Study of Akatinol Memantine in VaD in Russia
Status: COMPLETED
Conditions: Vascular Dementia
Interventions: DRUG: Akatinol Memantine 20 mg|DRUG: Akatinol Memantine 10 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Impact of the Level of Mindfulness on the Management of Patients With Recurrent Depressive Disorders by the Mindfulness Based Cognitive Therapy ( MBCT ): an Exploratory Study
Status: UNKNOWN
Conditions: Patients With Recurrent Depressive Disorders
Interventions: OTHER: Procurement questionnaires
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effects of Extraoral Photobiomodulation on the Rate of Orthodontic Alignment
Status: COMPLETED
Conditions: Malocclusion
Interventions: DEVICE: Extraoral OrthoPulse® PBM|OTHER: Fixed Orthodontic Appliance Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Er,Cr:YSGG Laser and Diode Laser in the Treatment of Gingival Melanin Pigmentation
Status: COMPLETED
Conditions: Pigmentation
Interventions: DEVICE: laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bioavailability Study of MGL-3196 Tablets Compared to Capsules
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: MGL-3196 Tablet|DRUG: MGL-3196 Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Improvement in Function on Foot Pressure, Balance and Gait in Children With Upper Extremity Affected
Status: COMPLETED
Conditions: Upper Extremity Dysfunction|Gait, Unsteady|Juvenile Idiopathic Arthritis|Balance
Interventions: OTHER: Exercise protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the MP Diagnostics HTLV Blot 2.4
Status: UNKNOWN
Conditions: HTLV-I Infections|HTLV-II Infections|Human T-lymphotropic Virus 1|Human T-lymphotropic Virus 2|HTLV I Associated T Cell Leukemia Lymphoma|HTLV I Associated Myelopathies
Interventions: OTHER: CDPHL Algorithm
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: TTM-based Intervention and MI in CHD Patients
Status: COMPLETED
Conditions: Coronary Heart Disease|Depression
Interventions: OTHER: Transtheoretical model-based (TTM - based) intervention and motivational interviewing (MI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Drug-Drug Interaction Between IDX719, Simeprevir, TMC647055 and Ritonavir When Administered in Combination in Healthy Participants (MK-1894-007)
Status: COMPLETED
Conditions: Hepatitis C, Chronic
Interventions: DRUG: IDX719|DRUG: Simeprevir|DRUG: TMC647055|DRUG: RTV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral Isotretinoin in Melasma a Randomized Controlled Trial
Status: RECRUITING
Conditions: Melasma
Interventions: DRUG: Isotretinoin|DRUG: Triple combination formula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study To Observe Treatment Patterns and Outcomes in Patients With HER2-Positive Unresectable Locally Advanced or Metastatic Breast Cancer
Status: WITHDRAWN
Conditions: Breast Cancer, HER2 Positive Breast Cancer, Metastatic Breast Cancer, Locally Advanced Breast Cancer
Interventions: OTHER: No intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Rivaroxaban for the Prevention of Major Cardiovascular Events in Coronary or Peripheral Artery Disease
Status: COMPLETED
Conditions: Prevention & Control
Interventions: DRUG: Rivaroxaban (Xarelto, BAY59-7939)|DRUG: Rivaroxaban (Xarelto, BAY59-7939)|DRUG: Aspirin|DRUG: Aspirin placebo|DRUG: Rivaroxaban placebo|DRUG: Pantoprazole|DRUG: Pantoprazole placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Assessing the Effectiveness of a Weight Watchers-based Lifestyle Intervention for the Primary Prevention of Type 2 Diabetes
Status: COMPLETED
Conditions: Prediabetes|Gestational Diabetes Mellitus|Obesity
Interventions: BEHAVIORAL: Weight Watchers|BEHAVIORAL: National Diabetes Education Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Haemorrhage Alleviation With Tranexamic Acid- Intestinal System
Status: COMPLETED
Conditions: Gastrointestinal Bleeding
Interventions: DRUG: Tranexamic Acid|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial to Assess the Efficacy and Safety of SPM 927 (Lacosamide) in Subjects With Painful Distal Diabetic Neuropathy
Status: COMPLETED
Conditions: Diabetic Neuropathy
Interventions: DRUG: SPM 927
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Systemic Avastin Therapy in Age-Related Macular Degeneration
Status: COMPLETED
Conditions: Macular Degeneration
Interventions: DRUG: Bevacizumab|DRUG: Sodium Chloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Slump Sitting X-ray of the Lumbar Spine Is Better Than Conventional Flexion View
Status: TERMINATED
Conditions: Low Back Pain|Spondylolisthesis
Interventions: RADIATION: Slump sitting|RADIATION: Forward bending
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Nutrient Support to Body Composition and Healthy Ageing
Status: COMPLETED
Conditions: Sarcopenia|Osteopenia
Interventions: DIETARY_SUPPLEMENT: CONTROL|DIETARY_SUPPLEMENT: PROTEIN|BEHAVIORAL: PHYSICAL ACTIVITY
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Study of Different Types of Fatty Acid on Risk Factors for Heart Disease
Status: COMPLETED
Conditions: Cardiovascular Risk Factors
Interventions: DIETARY_SUPPLEMENT: Absence or presence of fish oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Accuracy of Ultrasound Markers Versus Biochemical Markers in Prediction of Ovarian Response in Obese Women Undergoing IVF/ICSI Treatment
Status: UNKNOWN
Conditions: Invitro Fertilization
Interventions: DRUG: Long luteal phase GnRH agonist protocol|DRUG: Gonadotropins
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Test BI 764198 in People With a Type of Kidney Disease Called Focal Segmental Glomerulosclerosis
Status: RECRUITING
Conditions: Kidney Disease, Chronic
Interventions: DRUG: BI 764198|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Vaginal Misoprostol and Foley Catheter for Late Second Trimester Termination of Pregnancy
Status: COMPLETED
Conditions: Late Second Trimester Termination of Pregnancy
Interventions: DRUG: MisoprostoL|DEVICE: Foley Catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Clinical Features and Pregnancy Outcomes of CTD Patients
Status: RECRUITING
Conditions: Connective Tissue Diseases|Pregnancy Related
Interventions: DRUG: Prednisone|DRUG: Hydroxychloroquine|DRUG: Aspirin|DRUG: low molecular weight heparin Enoxaparin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Procedure for Duodenal-Ileal Diversion for Patients With Weight Regain Following Sleeve Gastrectomy
Status: ACTIVE_NOT_RECRUITING
Conditions: Obesity, Morbid
Interventions: DEVICE: Self Forming Magnetic (SFM) Anastomosis System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Neoadjuvant Treatment With Oxaliplatin -UFT- Radiotherapy in Rectal Cancer
Status: COMPLETED
Conditions: Rectal Neoplasms
Interventions: DRUG: OXALIPLATIN
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Intraperitoneally Administered AVB-001 in Patients With Serous Adenocarcinoma of the Ovary
Status: TERMINATED
Conditions: Neoplasm, Ovarian|Fallopian Tube Cancer|Primary Peritoneal Cavity Cancer|Adenocarcinoma Ovary|Serous Adenocarcinoma of Ovary|Serous Adenocarcinoma of Primary Peritoneum|Primary Peritoneal Carcinoma|High Grade Serous Adenocarcinoma
Interventions: DRUG: AVB-001 (Dose Escalation Phase)|DRUG: AVB-001 (Dose Expansion Phase)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Load-induced Changes in Glenohumeral Translation in Patients With Rotator Cuff Tear
Status: COMPLETED
Conditions: Rotator Cuff Tear
Interventions: DIAGNOSTIC_TEST: 3D motion analysis|DIAGNOSTIC_TEST: isometric shoulder strength by dynamometer|DIAGNOSTIC_TEST: fluoroscopic images of each shoulder|DIAGNOSTIC_TEST: Bilateral shoulder Magnetic Resonance Imaging (MRI)|OTHER: data collection by health questionnaires
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Phase Ib Expansion Study Investigating the Safety, Efficacy, and Pharmacokinetics of Intravenous CUDC-101 in Subjects With Advanced Head and Neck, Gastric, Breast, Liver and Non-small Cell Lung Cancer Tumors
Status: COMPLETED
Conditions: Head and Neck Cancer|Liver Cancer|Breast Cancer|Gastric Cancer|Non-Small Cell Lung Cancer
Interventions: DRUG: CUDC-101|DRUG: CUDC-101
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Therapeutic Patient Education on the Toxicity of Immune Checkpoint Inhibitors in Oncology
Status: ACTIVE_NOT_RECRUITING
Conditions: Therapeutic Patient Education|Immune Checkpoint Inhibitors|Melanoma|Advanced Non-small Cell Lung Cancer|Renal Cell Carcinoma|Head and Neck Cancer|Immune-related Adverse Event
Interventions: BEHAVIORAL: Therapeutic education program|BEHAVIORAL: Usual Information
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Child Discomfort and Parental Acceptability of Silver Diamine Fluoride and Alternative Restorative Treatment
Status: COMPLETED
Conditions: Dental Caries|Child Discomfort
Interventions: DRUG: SDF|DRUG: ART
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing the Intravenous Treatment of Skin Infections in Children, Home Versus Hospital
Status: COMPLETED
Conditions: Cellulitis
Interventions: OTHER: Home|OTHER: Ward|DRUG: ceftriaxone|DRUG: flucloxacillin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficiency of the Quadratus Lumborum Block for Post-operative Analgesia in Abdominoplasty Surgery
Status: RECRUITING
Conditions: Quadratus Lumborum Block|Abdominoplasty|Analgesia|Locoregional Anesthesia
Interventions: OTHER: QLB anesthesia|OTHER: Intravenous anesthesia without QLB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endoscopic Debridement of Chronic Plantar Fasciitis
Status: COMPLETED
Conditions: Fasciitis, Plantar|Fasciitis, Plantar, Chronic|Heel Spur
Interventions: PROCEDURE: Chronic plantar fasciitis endoscopic debridement coupled with heel spur resection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Slow Paced-Respiration Intervention to Reduce Incontinence Trial (SPIRIT)
Status: COMPLETED
Conditions: Urinary Incontinence, Urge
Interventions: DEVICE: RESPeRATE|OTHER: Urinary Incontinence Pamphlet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Alter-G Training on Gait and Balance in Diabetic Neuropathy Patients
Status: COMPLETED
Conditions: Diabetic Peripheral Neuropathy
Interventions: OTHER: Group- A (100% weight-bearing; n=14), (moderate-intensity (50-70% heart rate reserve) aerobic exercise training on the antigravity treadmill, 3 times/week for 12-weeks.|OTHER: Group- B (70% weight-bearing), (moderate-intensity (50-70% heart rate reserve) aerobic exercise training on the antigravity treadmill, 3 times/week for 12-weeks.|OTHER: Group- C (50% weight-bearing), (moderate-intensity (50-70% heart rate reserve) aerobic exercise training on the antigravity treadmill, 3 times/week for 12-weeks.|OTHER: Group- D (30% weight-bearing), (moderate-intensity (50-70% heart rate reserve) aerobic exercise training on the antigravity treadmill, 3 times/week for 12-weeks.|OTHER: Group- E; Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Relative Bioavailability of Olodaterol and Fluconazole
Status: COMPLETED
Conditions: Healthy|Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: BI 1744|DRUG: Fluconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Routine Use of Antiretroviral Therapy to Prevent Mother-to-Child HIV Transmission in the Kafue District of Zambia
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Routine three-drug antiretroviral prophylaxis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: HOME Study (Health Outcomes and Measures of the Environment Study)
Status: COMPLETED
Conditions: Environmental Exposures|Child Development|Lead and Injury Reduction
Interventions: PROCEDURE: Lead Hazard Control Intervention|PROCEDURE: Injury Hazard Control Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Walking for Recovery From Surgery in Improving Quality of Life in Older Adults With Lung or Gastrointestinal Cancer and Their Family Caregivers
Status: ACTIVE_NOT_RECRUITING
Conditions: Adult Liver Carcinoma|Caregiver|Colorectal Carcinoma|Lung Carcinoma|Malignant Digestive System Neoplasm|Pancreatic Carcinoma
Interventions: BEHAVIORAL: Exercise Intervention|OTHER: Quality-of-Life Assessment|OTHER: Survey Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Investigating the Use of Goal Management Therapy in Improving Cognitive Functioning in Public Safety Personnel With PTSD
Status: RECRUITING
Conditions: Post Traumatic Stress Disorder|Cognitive Deficit
Interventions: BEHAVIORAL: Goal Management Therapy|BEHAVIORAL: Psychosocial Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of VGX-3100 DNA Vaccine With Electroporation in Patients With Cervical Intraepithelial Neoplasia Grade 2/3 or 3
Status: COMPLETED
Conditions: Cervical Intraepithelial Neoplasia
Interventions: BIOLOGICAL: VGX 3100|BIOLOGICAL: Placebo|DEVICE: CELLECTRA™-5P
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Stellate Ganglion Block as Adjuvant Therapy to ca Channel Blocker
Status: COMPLETED
Conditions: Subarachnoid Hemorrhage
Interventions: PROCEDURE: stellate ganglion block by transcranial doppler|DRUG: Nimodipine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety Study of Platelets Treated for Pathogen Inactivation and Stored for Up to Seven Days
Status: COMPLETED
Conditions: Thrombocytopenia
Interventions: DEVICE: Transfusion of Pathogen Inactivated Platelets stored for 6-7 days
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION