pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Efficacy of Acetylcysteine in Patients Undergoing Surgery for Otosclerosis
Status: COMPLETED
Conditions: Otosclerosis
Interventions: DRUG: Acetylcysteine|DRUG: Placebo (NaCl)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Autologous Bone Marrow Derived Stem Cells for Acute Myocardial Infarction
Status: COMPLETED
Conditions: Myocardial Infarction
Interventions: BIOLOGICAL: MNC|BIOLOGICAL: AC 133|BIOLOGICAL: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Coagulation Factor VIIa Variant Marzeptacog Alfa (Activated) in Adult Subjects With Hemophilia A and B
Status: COMPLETED
Conditions: Hemophilia A With Inhibitor|Hemophilia B With Inhibitor
Interventions: BIOLOGICAL: Coagulation Factor VIIa variant
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Metformin for Abdominal Aortic Aneurysm Growth Inhibition
Status: ENROLLING_BY_INVITATION
Conditions: Abdominal Aortic Aneurysm
Interventions: DRUG: Metformin|OTHER: Standard care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Compare Outcome of Enhanced Recovery After Cesarean Surgery and Conventional Care
Status: COMPLETED
Conditions: To Determine Whether ERAS Can Reduce Length of Stay in Pregnant Women After Cesarean Section
Interventions: PROCEDURE: ERAS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase IIa Study of WBI-1001 Cream for Atopic Dermatitis
Status: COMPLETED
Conditions: Dermatitis, Atopic
Interventions: DRUG: WBI-1001
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Psychosocial Needs and Exploration of Online Support for Patients With Mesothelioma
Status: COMPLETED
Conditions: Mesothelioma
Interventions: BEHAVIORAL: Questionnaires & online virtual support group|BEHAVIORAL: Questionnaires & online virtual support group
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Strengthening Exercises in Shoulder Impingement (SExSI) Trial
Status: COMPLETED
Conditions: Subacromial Impingement Syndrome
Interventions: OTHER: Strengthen your Shoulder|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nimotuzumab Concurrent With Chemoradiotherapy for Patients With Unresectable Esophageal Squamous Cell Carcinoma
Status: RECRUITING
Conditions: Esophageal Cancer|Nimotuzumab|Chemoradiotherapy|Chemotherapy|Immunotherapy
Interventions: COMBINATION_PRODUCT: Nimotuzumab with chemoradiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Evaluate the Efficacy of Durvalumab + Anlotinib in Terms of OS and PFS.
Status: ACTIVE_NOT_RECRUITING
Conditions: Extensive-Stage Small-Cell Lung Cancer
Interventions: DRUG: durvalumab + anlotinib|DRUG: Durvalumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Puerto Rican Obesity Intervention for Men
Status: NOT_YET_RECRUITING
Conditions: Obesity
Interventions: BEHAVIORAL: TeleSalud Healthy Eating- Physical Activity/Sedentary Behavior (HE-PA/SB)|BEHAVIORAL: TeleSalud General Health Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Botulinum Toxin Type A Injection Into the Gastrocnemius Muscle for Treatment of Nocturnal Calf Cramps in Patients With Lumbar Spinal Stenosis
Status: COMPLETED
Conditions: Spinal Stenosis With Nocturnal Calf Cramps
Interventions: DRUG: botulinum toxin type A (Nabota®) injection into the gastrocnemius muscle|OTHER: no intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: High Flow Nasal Cannula Versus Non-Invasive Ventilation in Exacerbations of Chronic Obstructive Pulmonary Disease
Status: RECRUITING
Conditions: Exacerbation Copd|Acute Respiratory Distress|Acute Hypercapnic Respiratory Failure
Interventions: DEVICE: Non Invasive Ventilation|DEVICE: High Flow Oxygen Cannula 50|DEVICE: High Flow Oxygen Cannula 30
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Ledipasvir/Sofosbuvir, With or Without Ribavirin, in HCV Infected Participants Who Have Failed Prior Treatment With Sofosbuvir-based Therapies
Status: TERMINATED
Conditions: Hepatitis C Virus Infection
Interventions: DRUG: LDV/SOF|DRUG: RBV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Vemurafenib + Cobimetinib + Atezolizumab in Melanoma: NEO-VC
Status: TERMINATED
Conditions: Malignant Melanoma
Interventions: DRUG: Vemurafenib|DRUG: Cobimetinib|DRUG: Atezolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vaccine Therapy Plus Sargramostim and Chemotherapy in Treating Women With Stage II or Stage III Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: BIOLOGICAL: recombinant fowlpox-CEA(6D)/TRICOM vaccine|BIOLOGICAL: recombinant vaccinia-CEA(6D)-TRICOM vaccine|BIOLOGICAL: sargramostim|DRUG: cyclophosphamide|DRUG: doxorubicin hydrochloride|DRUG: paclitaxel|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Investigation of the Efficacy and Tolerability of a Cosmetic Product With Onabotulinumtoxin A in the Treatment of Facial Lines
Status: COMPLETED
Conditions: Wrinkles|Photoaging|Fine Lines
Interventions: PROCEDURE: Onabotulinumtoxin A|COMBINATION_PRODUCT: Facial Cleanser|COMBINATION_PRODUCT: Facial Moisturizer|COMBINATION_PRODUCT: Sunscreen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: First Time in Human Study of Long Acting VH4524184 Formulations
Status: RECRUITING
Conditions: HIV Infections
Interventions: DRUG: Oral VH4524184|DRUG: VH4524184 Formulation A SC|DRUG: Placebo Formulation A SC|DRUG: rHuPH20|DRUG: VH4524184 Formulation B SC|DRUG: Placebo Formulation B SC|DRUG: VH4524184 Formulation C SC|DRUG: Placebo Formulation C SC|DRUG: VH4524184 Formulation A IM|DRUG: Placebo Formulation A IM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intravitreal Bevasizumab VS Sham Treatment in Acute BRVO: A Randomized Clinical Trial
Status: COMPLETED
Conditions: Retinal Disease
Interventions: DRUG: Avastin (Bevacizumab)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: AI DErived Plaque Quantification: CCTA and AI-QCPA for Determining Effective CAD Management
Status: ENROLLING_BY_INVITATION
Conditions: Coronary Artery Disease
Interventions: DIAGNOSTIC_TEST: AI-enabled quantitative coronary plaque analysis (AI-QCPA)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Stress-induced Scratching in Healthy and AD
Status: COMPLETED
Conditions: Healthy|Atopic Dermatitis
Interventions: BEHAVIORAL: Trier Social Stress Test (TSST)|BEHAVIORAL: Landscape Video
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Local mEHT + TCM Versus Intraperitoneal Chemoinfusion in Treatment of Malignant Ascites: Phase II RCT
Status: COMPLETED
Conditions: Peritoneal Neoplasms|Ascites|Yang Deficiency|Yin Deficiency
Interventions: DEVICE: Modulated Electro-Hyperthermia (mEHT)|DIETARY_SUPPLEMENT: TCM Herbal Decoction (Shi Pi)|DRUG: IPCI (CDDP+5FU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Peri-operative Vitamin D Therapy for Hepatectomy
Status: NOT_YET_RECRUITING
Conditions: Vitamin D Deficiency|Hepatocellular Carcinoma|Perioperative Complication
Interventions: DIETARY_SUPPLEMENT: Vitamin D|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MEK and Autophagy Inhibition in Metastatic/Locally Advanced, Unresectable Neuroblastoma RAS (NRAS) Melanoma
Status: UNKNOWN
Conditions: Metastatic NRAS Melanoma
Interventions: DRUG: Trametinib plus hydroxychloroquine in patients with NRAS Melanoma (Dose 1)|DRUG: Trametinib plus hydroxychloroquine in patients with NRAS Melanoma (Dose 2)|DRUG: Trametinib plus hydroxychloroquine in patients with NRAS Melanoma (Dose 3)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Patent Foramen Ovale in Cryptogenic Stroke Study
Status: COMPLETED
Conditions: Ischemic Stroke|Patent Foramen Ovale
Interventions: DRUG: Warfarin|DRUG: Aspirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: CALERIE (PBRC, Baton Rouge) - Comprehensive Assessment of Long-Term Effects of Reducing Intake of Energy
Status: COMPLETED
Conditions: Aging|Cardiovascular Disease|Diabetes Mellitus
Interventions: BEHAVIORAL: Caloric Restriction (CR)|BEHAVIORAL: Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: PREVENTION
Clinical trial: Efficacy, Safety and Pharmacodynamic/Pharmacokinetic Study of Fimasartan (BR-A-657•K)
Status: COMPLETED
Conditions: Essential Hypertension
Interventions: DRUG: Placebo|DRUG: Fimasartan (BR-A-657•K) 20 mg|DRUG: Fimasartan (BR-A-657•K) 60 mg|DRUG: Fimasartan (BR-A-657•K) 180 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II Study of "VIPER" Chemotherapy in Rel/Ref DLBCL
Status: COMPLETED
Conditions: Non-Hodgkin's Lymphoma
Interventions: DRUG: bortezomib, dexamethasone, ifosfamide|DRUG: mesna, cisplatin, etoposide, rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The SIMBA Project - The Effect of a Prebiotic Supplement on Glucose Metabolism and Gut Microbiota in Obese Adults
Status: UNKNOWN
Conditions: Glucose Metabolism|Metabolic Syndrome|Gut Microbiota
Interventions: DIETARY_SUPPLEMENT: Fermented canola-seaweed|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Utility of Multisensory Body-Representation in Spinal Cord Injury (SCI) With Pain
Status: RECRUITING
Conditions: Spinal Cord Injuries|Neuropathic Pain
Interventions: OTHER: tDCS and bodily illusions
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Complete Mesocolon Excision vs Locoregional Lymphadenectomy in Sigmoid Colon Cancer (CMELL)
Status: COMPLETED
Conditions: Colorectal Cancer|Sigmoid Cancer
Interventions: PROCEDURE: Complete mesocolon excision|PROCEDURE: Conventional locoregional lymphadenectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Feasibility Study: Effect of Patient Decision Aids for Total Joint Replacement on Surgical Referrals
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: BEHAVIORAL: 1 Patient decision aid|BEHAVIORAL: 2 Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: HAIC of Oxaliplatin, and 2400 mg/m² 5-fu vs HAIC of Oxaliplatin, and 1200 mg/m² 5-fu for Unresectable HCC: a Randomised Phase 3 Non-inferiority Trial
Status: UNKNOWN
Conditions: HepatoCellular Carcinoma
Interventions: DRUG: 2400 mg/m² 5-fu|DRUG: 1200 mg/m² 5-fu
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Effects of Autologous Adipose-Derived Stromal Cells Delivered in Patients With Type II Diabetes
Status: WITHDRAWN
Conditions: Diabetes Mellitus Type II
Interventions: PROCEDURE: Harvesting and Implantation of Adipose-Derived Stromal Vascular Fraction (AD-SVF)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of the Enteric Hormone Glucagon-Like Peptide (GLP-2) on the Intestinal Blood Flow in Patients With Short Bowel Syndrome
Status: UNKNOWN
Conditions: Short Bowel Syndrome
Interventions: DRUG: GLP-2|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Matrix Metalloproteinase-1/Tissue Inhibitor of Metalloproteinase-1 (MMP-1/TIMP-1) Ratio and Diabetic Foot Ulcers
Status: COMPLETED
Conditions: Diabetic Foot Ulcer
Interventions: OTHER: Picture + MMPs and TIMP1 at week 0 and week 4
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: R-CHOP Versus R-CDOP as First-line Treatment for Elderly Patients With Diffuse Large-B-cell Lymphoma
Status: UNKNOWN
Conditions: Lymphoma, Large B-Cell, Diffuse
Interventions: DRUG: Pegylated liposomal doxorubicin|DRUG: Doxorubicin|DRUG: Rituximab|DRUG: Cyclophophamide|DRUG: Vincristine|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Human Anti-TNF Monoclonal Antibody D2E7 in Subjects With Active Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Adalimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Amatuximab for High Mesothelin Cancers
Status: TERMINATED
Conditions: Carcinoma, Pancreatic Ductal|Mesothelioma|Ovarian Neoplasms|Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: Amatuximab (MORab-009)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endophenotype for Alcohol Misuse in Healthy Minority Populations
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Naltrexone|DRUG: placebo|OTHER: alcohol|OTHER: Sham alcohol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Accelerating Gastrointestinal Recovery
Status: COMPLETED
Conditions: Ovarian Cancer|Fallopian Tube Cancer|Peritoneal Cancer
Interventions: DRUG: Alvimopan|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Accelerated Rehabilitation After Anterior Cruciate Ligament Reconstruction With and Without Suture Tape Reinforcement
Status: UNKNOWN
Conditions: ACL Injury
Interventions: PROCEDURE: ACL Reconstruction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Vitamin D3 Supplementation in Patients With Chronic Kidney Disease
Status: COMPLETED
Conditions: Chronic Kidney Disease|Insulin Resistance|Vitamin D Deficiency
Interventions: DRUG: cholecalciferol (TillVal-D)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety and Effectiveness Study of the Reflection Ceramic Acetabular System
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DEVICE: Reflection Ceramic-Ceramic Total Hip Replacement|DEVICE: Reflection FSO V Total Hip Replacement
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Icatibant (TAK-667) in Japanese Children and Teenagers With Acute Attacks of Hereditary Angioedema
Status: COMPLETED
Conditions: Hereditary Angioedema
Interventions: DRUG: TAK-667
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Evaluate the Effect of Clarithromycin on the Systemic Exposure of Pacritinib in Healthy Subjects
Status: COMPLETED
Conditions: Drug Interaction Study
Interventions: DRUG: Pacritinib|DRUG: Clarithromycin|DRUG: Pacritinib and Clarithromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Novel Limb Cryocompression System for Prevention of Chemotherapy Induced Peripheral Neuropathy
Status: UNKNOWN
Conditions: Chemotherapy-induced Peripheral Neuropathy
Interventions: DEVICE: Paxman Cryocompression System (PCCS)|DEVICE: Paxman Cryocompression System (PCCS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Total Therapy XVII for Newly Diagnosed Patients With Acute Lymphoblastic Leukemia and Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Lymphoblastic Leukemia|Acute Lymphoblastic Lymphoma
Interventions: DRUG: Prednisone|DRUG: Vincristine|DRUG: Daunorubicin|DRUG: Pegaspargase|DRUG: Erwinase®|DRUG: Cyclophosphamide|DRUG: Cytarabine|DRUG: Mercaptopurine|DRUG: Dasatinib|DRUG: Methotrexate|DRUG: Blinatumomab|DRUG: Ruxolitinib|DRUG: Bortezomib|DRUG: Dexamethasone|DRUG: Doxorubicin|DRUG: Etoposide|DRUG: Clofarabine|DRUG: Vorinostat|DRUG: Idarubicin|DRUG: Nelarabine|DRUG: Thioguanine|DRUG: Asparaginase Erwinia chrysanthemi (recombinant)-rywn|DRUG: Calaspargase Pegol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Booster Immunization With COVID-19 Vaccine,Inactivated Co -Administration With Influenza Vaccine and Pneumococcal Polysaccharide Vaccine
Status: COMPLETED
Conditions: COVID-19
Interventions: BIOLOGICAL: Adult group in immunogenicity and safety study of combined immunization|BIOLOGICAL: Elderly group in immunogenicity and safety study of combined immunization|BIOLOGICAL: Adult group in safety observation study of combined immunization|BIOLOGICAL: Elderly group in safety observation study of combined immunization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Rituximab, Acalabrutinib, and Durvalumab (RAD) in Primary CNS Lymphoma.
Status: RECRUITING
Conditions: Primary Central Nervous System Lymphoma (PCNSL)
Interventions: DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HIV Immune and Virological Responses Following the Administration of IL-2 Either Alone or Combined to ALVAC-HIV 1433 and HIV Lipopeptides in Patients Treated Early With HAART During Primary Infection
Status: TERMINATED
Conditions: HIV Infection
Interventions: DRUG: IL-2|BIOLOGICAL: LIPO-6T|BIOLOGICAL: ALVAC VIH 1433
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Low Fermentable Oligosaccharides, Disaccharides ,Monosaccharides and Polyols (FODMAP) Diet on Control of Pediatric Irritable Bowel Syndrome and Quality of Life
Status: COMPLETED
Conditions: Irritable Bowel Syndrome
Interventions: OTHER: low fodmap diet|OTHER: NICE guidelines for IBS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study With GFT505 (80mg) in Atherogenic Dyslipidaemic Patients With Abdominal Obesity
Status: COMPLETED
Conditions: Atherogenic Dyslipidaemia|Abdominal Obesity
Interventions: DRUG: GFT505 80mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Safety and Efficacy of LB1410 in Participants With Advanced Solid Tumor or Lymphoma（Keyplus-001）
Status: RECRUITING
Conditions: Solid Tumor|Lymphoma
Interventions: DRUG: LB1410
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Antenatal Support for Iron Deficiency Anemia
Status: RECRUITING
Conditions: Pregnancy Related|Anemia, Iron Deficiency|Anemia of Pregnancy
Interventions: DRUG: Ferumoxytol|DRUG: Ferrous Sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Web-Based Intervention Designed to Educate and Improve Adherence Through Learning to Use Continuous Glucose Monitoring
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus|Continuous Glucose Monitor
Interventions: BEHAVIORAL: Web-Based Education|BEHAVIORAL: Social Support|BEHAVIORAL: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Safety of Tropisetron in Preventing Emergence Delirium
Status: UNKNOWN
Conditions: Emergence Delirium|Postoperative Delirium
Interventions: DRUG: Tropisetron|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Alvelestat (MPH966), an Oral Neutrophil Elastase Inhibitor, in Bronchiolitis Obliterans Syndrome After Allogeneic Hematopoietic Stem Cell Transplantation
Status: RECRUITING
Conditions: Chronic Graft vs Host Disease|Chronic Graft-Versus-Host Disease|Bronchiolitis Obliterans Syndrome
Interventions: DRUG: MPH966
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: IDEAL Blood Pressure Management During Endovascular Therapy for Acute Ischemic Stroke
Status: COMPLETED
Conditions: Acute Ischemic Stroke
Interventions: PROCEDURE: Individualized blood pressure management|PROCEDURE: Standard blood pressure management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: ADAM17 Inhibitor/ Rituximab After Auto HCT for DLBCL
Status: COMPLETED
Conditions: Diffuse Large B Cell Non-Hodgkin Lymphoma
Interventions: DRUG: Rituximab|DRUG: INCB7839
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Contingency Management for Opioid and Stimulant Use Disorders in Primary Care
Status: ACTIVE_NOT_RECRUITING
Conditions: Opioid Use Disorder|Stimulant Use Disorder
Interventions: BEHAVIORAL: Contingency Management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Evaluate the Effectiveness, Safety, and Tolerability of Oxymorphone Immediate Release (IR) Oral Liquid in Post Surgical Pediatric Subjects
Status: TERMINATED
Conditions: Post-Operative Pain|Acute Pain
Interventions: DRUG: Oxymorphone HCl|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acute Optic Neuritis Network: an International Study That Invesitages Subjects With a First-ever Episode of Acute Inflammation of the Optic Nerve
Status: RECRUITING
Conditions: Demyelinating Diseases|Multiple Sclerosis|Neuromyelitis Optica Spectrum Disorder Attack|Myelin Oligodendrocyte Glycoprotein Antibody-associated Disease|Optic Neuritis
Interventions: OTHER: non-interventional study
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Intubation During Cardiopulmonary Resuscitation
Status: COMPLETED
Conditions: Endotracheal Intubation
Interventions: DEVICE: Macintosh laryngoscope|DEVICE: TruView EVO2 laryngoscope|DEVICE: TruView EVO2 PCD laryngoscope|DEVICE: ETView SL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Search for Predictors of Therapeutic Response in Ovarian Carcinoma
Status: COMPLETED
Conditions: Carcinoma of the Ovary|Fallopian Tube Cancer|Peritoneal Serous-type Advanced Stage
Interventions: OTHER: blood samples|OTHER: blood samples
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: A Study of PRT-201 Administered After Arteriovenous Graft (AVG) Creation in Patients With Chronic Kidney Disease
Status: COMPLETED
Conditions: Chronic Kidney Disease
Interventions: DRUG: PRT-201|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness and Safety of Adjuvant Software Based on Virtual Reality for Post-thoracoscopic Surgery Pain
Status: RECRUITING
Conditions: Acute Postoperative Pain|Video-assisted Thoracic Surgery|Virtual Reality
Interventions: DEVICE: VR-assisted postoperative analgesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Three Steps Hysteroscopic Repair of Post Caesarean Isthmocele in Patients With Post Menstrual Spotting
Status: UNKNOWN
Conditions: Abnormal Uterine Bleeding
Interventions: PROCEDURE: three steps hysteroscopic resection of an isthmocele
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Erythropoietin to Prevent Acute Kidney Injury in Chronic Kidney Disease Patients Undergoing Cardiac Surgery
Status: UNKNOWN
Conditions: Acute Renal Failure
Interventions: DRUG: beta erythropoietin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Clinical Trial of Group ACYW135 Meningococcal Polysaccharide Vaccine 003
Status: COMPLETED
Conditions: Meningitis
Interventions: BIOLOGICAL: ACYW135 Meningococcal Polysaccharide Vaccine|BIOLOGICAL: A+C Meningococcal Polysaccharide Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of LY573636-Sodium in the Treatment of Patients With Metastatic Soft Tissue Sarcoma
Status: COMPLETED
Conditions: Sarcoma, Soft Tissue
Interventions: DRUG: LY573636-sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Integrated Care on Delaying Chronic Kidney Disease Progression in Rural Communities of Thailand
Status: COMPLETED
Conditions: Chronic Kidney Disease
Interventions: BEHAVIORAL: Integrated Chronic Kidney Disease care|BEHAVIORAL: Conventional CKD care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pain Neuroscience Education in Patients With Total Knee Arthroplasty
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: OTHER: Pain Neuroscience Education|OTHER: Standard Physiotherapy Program (SPP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy Plus Oblimersen in Treating Patients With Previously Untreated Extensive-Stage Small Cell Lung Cancer
Status: COMPLETED
Conditions: Extensive Stage Small Cell Lung Cancer
Interventions: BIOLOGICAL: oblimersen sodium|DRUG: carboplatin|DRUG: etoposide|OTHER: pharmacological study|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Switching Study From Warfarin to Rivaroxaban
Status: COMPLETED
Conditions: Venous Thrombosis
Interventions: DRUG: Warfarin (Coumadin)|DRUG: Rivaroxaban (Xarelto, BAY59-7939)|DRUG: Placebo|DRUG: Vitamin K (Konakion)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: Effect of Sleep Restriction on Adipose Tissue and Skeletal Muscle Insulin Sensitivity
Status: COMPLETED
Conditions: Sleep Disturbance|Postmenopausal Symptoms|Insulin Sensitivity|Cardiovascular Risk Factor
Interventions: BEHAVIORAL: Sleep Restriction|BEHAVIORAL: Habitual Sleep
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: RESOLUTE Trial Aims to Investigate the Value of Adding Local Ablative Treatment to Standard Systemic Treatment for Unresectable Oligometastatic Colorectal Cancer
Status: RECRUITING
Conditions: Colorectal Cancer|Oligometastatic Disease
Interventions: PROCEDURE: Local Ablative Therapy|PROCEDURE: Standard first-line systemic treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Normobaric Hyperoxia Combined With Endovascular Treatment in Acute Ischemic Stroke (OPENS-2)
Status: COMPLETED
Conditions: Stroke, Acute|Neuroprotection
Interventions: DRUG: Normobaric Hyperoxia|DRUG: Sham Normobaric Hyperoxia|PROCEDURE: Endovascular Thrombectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Saxagliptin Treatment on Myocardial Fat Content, and Monocyte Inflammation
Status: TERMINATED
Conditions: Impaired Glucose Tolerance
Interventions: DRUG: Saxagliptin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Single Shot Intrathecal Analgesia in Vaginal Delivery
Status: RECRUITING
Conditions: Effectiveness of Single Shot Intra-thecal Analgesia in Multiparous Women Scheduled for Normal Vaginal Delivery
Interventions: DRUG: Dexmedetomidine|DRUG: Fentanyl|DRUG: Bupivacaine Hcl 0.5% Inj
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Management of Glycemia Following a Pizza Meal
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: OTHER: the patients ate a pizza that fermented for 8 hours|OTHER: the patients ate a pizza that fermented for 24 hours
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effectiveness of Transcutaneous Electrical Nerve Stimulation During Labor.
Status: COMPLETED
Conditions: Midwifery|Pregnancy
Interventions: DEVICE: TENS 1|DEVICE: TENS 2|DEVICE: Placebo TENS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Beetroot Juice Resistance Training Older Adults
Status: COMPLETED
Conditions: Sarcopenia|Old Age; Atrophy
Interventions: DIETARY_SUPPLEMENT: BRJ+Nitrate|DIETARY_SUPPLEMENT: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Real-Time Instrument for Acetabular Shell Positioning
Status: TERMINATED
Conditions: Total Hip Arthroplasty
Interventions: DEVICE: Real-time Instrumentation|PROCEDURE: Standard Total Hip Arthroplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fibroblast Activating Protein Inhibitor PET Imaging in Lupus Nephritis
Status: RECRUITING
Conditions: Lupus Nephritis
Interventions: DIAGNOSTIC_TEST: 68Ga-FAPI-04 PET
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Platform of Randomized Adaptive Clinical Trials in Critical Illness
Status: RECRUITING
Conditions: Respiratory Insufficiency|Extracorporeal Membrane Oxygenation Complication|Mechanical Ventilation Pressure High
Interventions: OTHER: Ultra-Protective Ventilation Facilitated by Extracorporeal Support|OTHER: Lung-Protective Ventilation (LPV)|OTHER: Driving Pressure-Limited Ventilation (DPL)|OTHER: Lung- and Diaphragm-Protective Ventilation and Sedation (LDPVS)|DRUG: Early Cohort corticosteroid dose|DRUG: Extended Cohort corticosteroid dose|DRUG: Usual care without routine corticosteroids|DRUG: Usual care without extending corticosteroids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Effect of Posterior Cervical Weighting and Deep Cervical Flexion Exercise on Forward Head Posture
Status: COMPLETED
Conditions: Postural Kyphosis|Neck Pain|Deformity of Spine|Deformity|Muscle Weakness|Neck Syndrome|Forward Head Posture|Brace
Interventions: DEVICE: Neck orthosis - with posterior cervical weight|OTHER: Deep cervical flexors exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 1/2 Study of Autologous SCG142 TCR T Cells in Patients With HPV16/52-positive Carcinoma
Status: NOT_YET_RECRUITING
Conditions: HPV-Related Squamous Cell Carcinoma|HPV-Related Cervical Squamous Cell Carcinoma|HPV-Related Vulvar Squamous Cell Carcinoma|HPV-Related Penile Squamous Cell Carcinoma|HPV-Related Vaginal Squamous Cell Carcinoma|HPV-Related Anal Squamous Cell Carcinoma|HPV-Related Head and Neck Cancer
Interventions: BIOLOGICAL: SCG142|DRUG: Cyclophosphamide|DRUG: Fludarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vorapaxar on Thrombin Generation and Coagulability
Status: COMPLETED
Conditions: Coronary Artery Disease|Peripheral Vascular Disease|Myocardial Infarction
Interventions: DRUG: Vorapaxar|DRUG: Vorapaxar and Aspirin|DRUG: Vorapaxar and Clopidogrel|DRUG: Vorapaxar, Aspirin, and Clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: NeisVac-C Single Prime Study in Infants
Status: COMPLETED
Conditions: Neisseria Meningitidis
Interventions: BIOLOGICAL: Meningococcal group C polysaccharide conjugate vaccine|BIOLOGICAL: Pneumococcal 13-valent conjugate vaccine|BIOLOGICAL: Combined Diphtheria-Tetanus-acellular Pertussis (DTPa), Hepatitis B, Poliovirus and Haemophilus influenzae type b vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Manual Therapy on Sensory Features in Patients With Cervical Radiculopathy
Status: COMPLETED
Conditions: Cervical Radiculopathy
Interventions: OTHER: manual therapy|OTHER: Superficial soft tissue massage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Open-Label Trial Of Reduced- Dose Pylera, Amoxicillin, and Esomeprazole in the Treatment Of Helicobacter Pylori Infection
Status: WITHDRAWN
Conditions: Treatment of H. Pylori Infection
Interventions: DRUG: Pylera based reduced regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Process and Effect Evaluation of the Project "Aan Tafel in 1,2,3 Euro"
Status: COMPLETED
Conditions: Consumer Behavior|Food Selection
Interventions: BEHAVIORAL: The intervention "Aan Tafel in 1, 2, 3 euro"
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparison of Using Collagen Membrane and A-PRF Using VISTA Technique in Gingival Recession Treatment
Status: ACTIVE_NOT_RECRUITING
Conditions: Gingival Recession
Interventions: PROCEDURE: vestibular incision sub periosteal tunnel access ( VISTA) technique.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Perioperative Intravenous Lidocaine on Opioid Consumption and Pain After Laparoscopic Totally Extraperitoneal Inguinal Hernioplasty
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: DRUG: Lidocaine|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomised, Double-blind, Placebo-controlled, Parallel-group Trial to Assess Clinical Efficacy of NNC0114-0006 in Subjects With Active Rheumatoid Arthritis
Status: COMPLETED
Conditions: Inflammation|Rheumatoid Arthritis
Interventions: DRUG: NNC0114-0006|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Subanesthetic Concentrations of Isoflurane/Nitrous Oxide - 3
Status: COMPLETED
Conditions: Opioid-Related Disorders|Substance-Related Disorders
Interventions: DRUG: 30% N2O|DRUG: 0.2% isoflurane|DRUG: 0.4% isoflurane|OTHER: 100% oxygen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Embryo Kinetics and Stimulation Protocol: Recombinant Follicle Stimulating Hormone (FSH) Versus Human FSH
Status: TERMINATED
Conditions: Embryo Kinetics
Interventions: PROCEDURE: Stimulation with human FSH|PROCEDURE: Stimulation with recombinant FSH
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Vitamin C on Postoperative Pain After Laparoscopic Cholecystectomy
Status: UNKNOWN
Conditions: Chronic Cholecystitis|Cholelithiasis
Interventions: DRUG: Vitamin C|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ovitex in Paraesophageal and Large Hiatal Hernia Repair
Status: RECRUITING
Conditions: Paraesophageal Hernia|Large Hiatal Hernia
Interventions: DEVICE: Ovitex LPR
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Denver Garden Environment and Microbiome Study Disease
Status: COMPLETED
Conditions: Diet Modification|Physical Activity|Weight Gain|Chronic Disease|Lifestyle, Sedentary|Health Behavior
Interventions: BEHAVIORAL: Community Garden Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Development of a "Mother/Child, Screen, Treat and Vaccinate Program" in Manchay and Iquitos, Peru
Status: COMPLETED
Conditions: Cervical Intraepithelial Neoplasia|Cervical Cancer|Cervical Neoplasm|Cervical Dysplasia|Human Papillomavirus
Interventions: BIOLOGICAL: Gardasil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Photodynamic Therapy for Oral Precursor Lesions
Status: COMPLETED
Conditions: Leukoplakia|Lichen
Interventions: OTHER: Aminolaevulinic acid|OTHER: Methylcellulose Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial Evaluating Technosphere® Insulin Versus Insulin Aspart in Subjects With Type 1 Diabetes Mellitus Over a 24-week Treatment Period
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus
Interventions: DRUG: Technosphere® Insulin with MedTone C Inhaler|DRUG: Technosphere ®Insulin with Gen2 Inhaler|DRUG: Insulin Aspart in combination with a basal insulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Ultrasound Real-time Guidance Technique on the Effectiveness and Safety of Labor Analgesia
Status: RECRUITING
Conditions: Labor Analgesia
Interventions: DEVICE: Ultrasound Real-time Guidance combined with Dural Puncture Epidural Labor Analgesia|DEVICE: Dural Puncture Epidural Labor Analgesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Dose Evaluation Study for the Latanoprost Punctal Plug Delivery System (L-PPDS) in Subjects With Ocular Hypertension or Open-Angle Glaucoma
Status: COMPLETED
Conditions: Glaucoma|Ocular Hypertension (OH)
Interventions: DRUG: Latanoprost-PPDS
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Kindness is Lesser Preferable Than Happiness: Investigating Interest in Different Effects of the Loving-kindness and Compassion Meditations
Status: COMPLETED
Conditions: Meditation
Interventions: BEHAVIORAL: LKCM(Loving-kindness and Compassion Meditations)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: BKM120 Combined With Vemurafenib (PLX4032) in BRAFV600E/K Mutant Advanced Melanoma
Status: COMPLETED
Conditions: BRAF Mutant Metastatic Melanoma
Interventions: DRUG: BKM120 Combined with Vemurafenib (PLX4032)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cryopreservation of Prepubertal Testicular Tissue for Preservation of Fertility in Young Boys With Cancer
Status: RECRUITING
Conditions: Fertility Disorders|Childhood Cancer
Interventions: PROCEDURE: Testicular Biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Centralized IIS-based Reminder/Recall to Increase Childhood Influenza Vaccination Rates
Status: COMPLETED
Conditions: Reminder Systems|Influenza Vaccines
Interventions: BEHAVIORAL: Reminder notifications via autodialer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Effects of a Life Coaching Seminar on Gratitude and Psychological Well-Being
Status: COMPLETED
Conditions: Psychological|Depression, Anxiety|Psychological Stress|Mental Health Wellness 1|Mental Stress|Mental Depression
Interventions: BEHAVIORAL: Tony Robbins Date with Destiny
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Research Program Targeting Pre- and Peri-transplant Optimization Program (R-PPOP)
Status: UNKNOWN
Conditions: Hematologic Malignancy
Interventions: BEHAVIORAL: Interval training|BEHAVIORAL: Psychiatric consult|BEHAVIORAL: Nutrition/diet evaluation|BEHAVIORAL: Referral to Social Worker
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Safety and Efficacy of TLD in Patients With COPD
Status: ACTIVE_NOT_RECRUITING
Conditions: COPD
Interventions: DEVICE: Targeted Lung Denervation (TLD)|OTHER: Optimal Medical Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Two Formulations of Febuxostat 120 mg Film-coated Tablets in Healthy Adult Volunteers After a Single Oral Dose Administration Under Fasting Conditions
Status: COMPLETED
Conditions: Bioequivalence
Interventions: DRUG: Febuxostat|DRUG: Adenuric
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: The Present Study Aims to Compare Patients Who Receive the Investigational Product (177Lu-DOTA-rosopatamab) Plus Standard of Care, in Comparison to Standard of Care Only
Status: RECRUITING
Conditions: Metastatic Prostate Cancer
Interventions: OTHER: 177Lu-DOTA-rosopatamb|DRUG: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT