pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Trial of a Behavior Change Intervention to Increase Aerobic and Resistance Exercise and Quality of Life in Older Prostate and Breast Cancer Survivors
Status: COMPLETED
Conditions: Quality of Life|Physical Activity|Fatigue|Breast Cancer|Prostate Cancer
Interventions: BEHAVIORAL: Two-time implementation intention|BEHAVIORAL: One-time implementation intention|BEHAVIORAL: Sham Comparator|BEHAVIORAL: Physical Activity Materials
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Immunogenicity and Safety of AdimFlu-S 2011-2012 in Non-Elderly Adult and Elderly Subjects
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: non-elderly aged between 18 and 60|BIOLOGICAL: elderly aged over 60
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Testing Mediators and Moderators of a Fotonovela for Depression to Promote Help-seeking Behavior
Status: UNKNOWN
Conditions: Mental Health Literacy
Interventions: BEHAVIORAL: Fotonovela|BEHAVIORAL: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Study Evaluating Platinum-Pemetrexed-Atezolizumab (+/-Bevacizumab) for Patients With Stage IIIB/IV Non-squamous Non-small Cell Lung Cancer With EGFR Mutations, ALK Rearrangement or ROS1 Fusion Progressing After Targeted Therapies
Status: RECRUITING
Conditions: NSCLC Stage IIIB|NSCLC Stage IV|EGFR Gene Mutation|ALK Gene Rearrangement Positive|ROS1 Gene Mutation
Interventions: DRUG: Carboplatin + Pemetrexed + Atezolizumab + Bevacizumab|DRUG: Carboplatin + Pemetrexed + Atezolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Liver Fibrosis in Alpha-1 Antitrypsin Deficiency (Liver AATD)
Status: COMPLETED
Conditions: Liver Fibrosis|Alpha-1 Antitrypsin Deficiency|AAT Deficiency|AATD
Interventions: DEVICE: Abdominal ultrasound|PROCEDURE: History and physical|PROCEDURE: Intravenous catheter|PROCEDURE: Blood draw|OTHER: Liver questionnaire|PROCEDURE: Liver Biopsy|DRUG: Midazolam|DRUG: Fentanyl|DRUG: Lidocaine|DRUG: Acetaminophen|DRUG: Lorazepam|DRUG: Oxycodone/Acetaminophen|DRUG: Ondansetron
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Bioequivalence of Telmisartan/ HCTZ Fixed Dose Combination Compared With Its Monocomponents in Healthy Male Volunteers II
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Telmisartan and HCTZ|DRUG: Telmisartan|DRUG: HCTZ
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diagnosis of Septicaemia by Detection of Microbial DNA in Blood in Severe Infections
Status: COMPLETED
Conditions: Febrile Neutropenia|Endocarditis|Severe Sepsis
Interventions: OTHER: Detection of microbial DNA in blood by SeptiFast®|OTHER: detection of microbial DNA in blood by blood culture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: FOAM-study, Cost Minimization Study Comparing Surgery Versus Duplex Guided Foam Sclerotherapy of Varicose Veins
Status: COMPLETED
Conditions: Varicose Vein Disease
Interventions: PROCEDURE: high ligation and stripping (surgery)|PROCEDURE: FOAM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Prefilled Liquid Etanercept(Yisaipu) for Active Ankylosing Spondylitis
Status: COMPLETED
Conditions: Ankylosing Spondylitis
Interventions: DRUG: prefilled liquid etanercept(Yisaipu)|DRUG: lyophilized etanercept powder(Yisaipu)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Programs to Improve Blood Pressure Treatment Adherence
Status: COMPLETED
Conditions: Cardiovascular Diseases|Heart Diseases|Hypertension
Interventions: BEHAVIORAL: Nurse administered|DEVICE: BP Monitor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pegylated Interferon Alfa-2a for Dialysis Patients With Acute Hepatitis C
Status: COMPLETED
Conditions: Hepatitis C
Interventions: DRUG: Pegylated interferon alfa-2a
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of SHR-A1811 as Neoadjuvant Treatment for Patients With HR-Positive, Low HER2 Expression Breast Cancer
Status: RECRUITING
Conditions: HER2 Low Breast Carcinoma
Interventions: DRUG: SHR-A1811 for injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Amplification of Zinc Finger Protein 217 Gene in Multiple Myeloma
Status: UNKNOWN
Conditions: Multiple Myeloma
Interventions: GENETIC: zinc-finger protein 217 gene
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Combination Chemotherapy in Treating Patients With Relapsed Acute Myelogenous Leukemia
Status: UNKNOWN
Conditions: Leukemia
Interventions: DRUG: cytarabine|DRUG: idarubicin|PROCEDURE: allogeneic bone marrow transplantation|PROCEDURE: autologous bone marrow transplantation|PROCEDURE: peripheral blood stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Electrocardiographic Diagnostic Performance of the Apple Watch Augmented With an Artificial Intelligence Algorithm
Status: COMPLETED
Conditions: Atrial Fibrillation|Tachycardia|Bradycardia|Premature Supraventricular Beat|Premature Ventricular Contraction
Interventions: DEVICE: Cardiologs Platform
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of Health and Social Interventions Aimed to Old People Discharged From Hospital After a Hip or Wrist Fracture Due to a Fall
Status: COMPLETED
Conditions: Elderly|Wrist Fracture|Hip Fracture
Interventions: PROCEDURE: Surgery or non-invasive procedure (reduction of the fracture, immobilization, stabilization)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Promoting Home Smoking Restrictions: Biomarker Feedback to Smoking and Non-Smoking Adults
Status: COMPLETED
Conditions: Smoking Cessation|Tobacco Use Disorder
Interventions: OTHER: Self-help brochure|OTHER: Biomarker feedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of the Difference Between Anorexia Nervosa With a History of Psychological Trauma and Classical Anorexia Nervosa on the Neurocognitive and Neurophysiological Factors
Status: RECRUITING
Conditions: Anorexia Nervosa
Interventions: BEHAVIORAL: Exposition Test
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Prospective Study to Evaluate Continuous Positive Airway Pressure Devices to Reduce Pulmonary Dose
Status: RECRUITING
Conditions: Lung Cancer|Left Sided Breast Cancer
Interventions: DEVICE: Continuous Positive Airway Pressure|OTHER: Deep inspiratory breath hold|OTHER: Free Breath
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Trial to Assess the Safety and Efficacy of Prophylactic TicagrelOr With Acetylsalicylic Acid Versus CLopidogrel With Acetylsalicylic Acid in the Development of Cerebrovascular EMbolic Events During TAVI
Status: COMPLETED
Conditions: Aortic Valve Stenosis
Interventions: DRUG: Ticagrelor plus ASA|DRUG: Clopidogrel plus ASA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Erlotinib in Combination With Select Tyrosine Kinase Inhibitors in Adult Patients With Advanced Solid Tumors
Status: NOT_YET_RECRUITING
Conditions: Neoplasms
Interventions: DRUG: Erlotinib|DRUG: Lenvatinib|DRUG: Axitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of First-Line Oral Hypoglycemics in Bone Markers of Treatment Naïve Saudi Adults With Type 2 Diabetes
Status: NOT_YET_RECRUITING
Conditions: Diabetes Type 2|Osteoporosis
Interventions: DRUG: Metformin|BEHAVIORAL: Lifestyle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Randomized Clinical Trial to Evaluate Solutions for the Management of Virologic Failure on TLD in Sub-Saharan Africa
Status: RECRUITING
Conditions: HIV Infections|AIDS|Virologic Failure
Interventions: OTHER: Standard of Care treatment strategy|OTHER: Individualized Care treatment strategy|OTHER: Immediate Switch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Novel Functional Imaging Technique With FLT-PET/MRI For Staging, Response Assessment and Radiation Treatment Planning in Cervix Cancer
Status: UNKNOWN
Conditions: Image, Body|Cervix Cancer
Interventions: DIAGNOSTIC_TEST: [18F]FLT-PET/MRI body scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Hyperthermia Combined With Immunotherapy in the Treatment of Abdominal and Pelvic Malignancies or Metastases
Status: COMPLETED
Conditions: Cancer|Abdominal Cancer|Pelvic Cancer|Metastatic Cancer|Peritoneal Metastases|Liver Metastases
Interventions: DEVICE: Thermotron RF-8|BIOLOGICAL: Adoptive cellular Immunotherapy|DRUG: Anti-PD-1 antibody|DRUG: Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Dose-Finding Study of TM-601 in Adults With Recurrent Malignant Glioma
Status: UNKNOWN
Conditions: Malignant Glioma|Glioblastoma Multiforme|GBM|Astrocytoma|Oligodendroglioma
Interventions: DRUG: TM-601
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Study of Ribose, Uridine, and Thymidine for a Complex Syndrome Involving Excessive 5'-Nucleotidase Activity
Status: COMPLETED
Conditions: 5'-Nucleotidase Syndrome
Interventions: DRUG: ribose|DRUG: thymidine|DRUG: uridine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Ultrasound-guided Combined Spinal-epidural Anesthesia: Pre-procedure Versus Real-time Scan
Status: UNKNOWN
Conditions: Regional Anesthesia Morbidity|Ultrasonography
Interventions: PROCEDURE: realtime ultrasonography|PROCEDURE: prescan ultrasonography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Ultrasound-Guided Mid-Point Transverse Process to Pleura Block for Thoracotomy Incisions
Status: UNKNOWN
Conditions: Pre-emptive|Postoperative Pain|Thoracotomy
Interventions: PROCEDURE: Midpoint transverse process block group|PROCEDURE: Sham group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of a Mixture of Fibers and Carbohydrates on Intestinal Transit in Children Diagnosed With Functional Constipation
Status: UNKNOWN
Conditions: Constipation - Functional
Interventions: DIETARY_SUPPLEMENT: Mixture of fibers + Placebo|DIETARY_SUPPLEMENT: Placebo + Mixture of fibers
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Resistance Training and Injection Treatment for Achilles Enthesopathy
Status: ACTIVE_NOT_RECRUITING
Conditions: Achilles Entesopathy
Interventions: DRUG: Corticosteroid injection|DRUG: Local anesthesia injections
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Connection Between Gait Variability Parameters and Balance Performance in Children With Physical Disability
Status: COMPLETED
Conditions: Brain Injury|Cerebral Palsy
Interventions: OTHER: walking and balance performance evaluation|PROCEDURE: muscle strength, walking and balance performance
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: STOMP Early Years: A Pilot RCT of an Intensive, Family-Centred, Home Visiting Intervention for Young Children With Severe Obesity
Status: COMPLETED
Conditions: Child Obesity
Interventions: BEHAVIORAL: Parenting education sessions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effects of a Biostimulator and Dermal Fillers for Cheek Augmentation and Contour Deficiencies
Status: RECRUITING
Conditions: Photoaging|Weight Loss|Skin Laxity|Photodamaged Skin|Volume Deficiency of the Midface
Interventions: DEVICE: Sculptra treatment|DEVICE: Restylane Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Next Generation Sequencing of Normal Tissues Prospectively in Pediatric Oncology Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Solid, Liquid, Central Nervous System Tumors
Interventions: OTHER: Study Introduction Visit|OTHER: Informed Consent Visit|OTHER: Informed Consent Follow-Up Visit|OTHER: Return of Results Conversation|OTHER: Return of Results Follow-Up Visits|PROCEDURE: Blood Sample|PROCEDURE: Skin Biopsy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Matrion™ Decellularized Placental Membrane in Subjects With Diabetic Foot Ulcers
Status: RECRUITING
Conditions: Diabetic Foot|Lower Extremity Wound
Interventions: OTHER: Matrion|OTHER: Conventional Care Wound Management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intraoperative Ultrasound in Laparoscopic or Robotic Myomectomy Patients
Status: TERMINATED
Conditions: Fibroid Uterus|Quality of Life
Interventions: PROCEDURE: Intraoperative contact ultrasonography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Everolimus and Letrozole in Treating Patients With Recurrent Hormone Receptor Positive Ovarian, Fallopian Tube, or Primary Peritoneal Cavity Cancer
Status: COMPLETED
Conditions: Ovarian Endometrioid Adenocarcinoma|Ovarian Seromucinous Carcinoma|Ovarian Serous Cystadenocarcinoma|Ovarian Serous Surface Papillary Adenocarcinoma|Recurrent Fallopian Tube Carcinoma|Recurrent Ovarian Carcinoma|Recurrent Ovarian Germ Cell Tumor|Recurrent Primary Peritoneal Carcinoma|Undifferentiated Ovarian Carcinoma
Interventions: DRUG: Everolimus|OTHER: Laboratory Biomarker Analysis|DRUG: Letrozole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Therapeutic Endoscopic Ultrasound for Gastrointestinal Disorders: A Multicenter Registry Study
Status: ENROLLING_BY_INVITATION
Conditions: Therapeutic Endoscopic Ultrasound|Advanced Endoscopy|Therapeutic Endoscopy|Interventional Endoscopy|Interventional Endoscopic Ultrasound|Gastro-Intestinal Disorder|Gastrointestinal Disease|Gastrointestinal Cancer|Gastrointestinal Dysfunction|Gastrointestinal Fistula|Gastrointestinal Infection|Gastrointestinal Injury|Pancreatic Disease|Bile Duct Diseases
Interventions: PROCEDURE: Therapeutic Endoscopic Ultrasound
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Proof-of-Concept Study Investigating the Safety and Efficacy of ZT-031 on Hip Fracture Healing in Men and Postmenopausal Women
Status: WITHDRAWN
Conditions: Hip Fracture
Interventions: DRUG: ZT-031|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficiency and Safety of Sodium Bicarbonate on Uric Acid in Patients With Asymptomatic Hyperuricemia or Gout
Status: UNKNOWN
Conditions: Asymptomatic Hyperuricemia|Gout
Interventions: DRUG: Sodium Bicarbonate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Analytical Treatment Interruption (ATI) to Assess the Immune System's Ability to Control HIV in Participants Who Became HIV-infected During the HVTN 704/HPTN 085 AMP Study
Status: COMPLETED
Conditions: HIV Infection
Interventions: OTHER: Analytical Treatment Interruption
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Opioid-free Vs Traditional Balanced Anesthesia in Laparoscopic Colorrectal Surgery
Status: RECRUITING
Conditions: Colorectal Surgery
Interventions: DRUG: Opioid free anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Long-term Safety of CC-486 (Oral Azacitidine) in Subjects With Hematological Disorders
Status: ACTIVE_NOT_RECRUITING
Conditions: Hematologic Neoplasm|Neoplasms|Hematologic Malignancies
Interventions: DRUG: CC-486
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: New Options for Preoperative Anesthesia in Intrauterine Needling
Status: COMPLETED
Conditions: Stress|Pain
Interventions: DRUG: Remifentanil|DRUG: saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study On The Role Of Nitric Oxide In Alpha 1-Adrenergic Vasoreactivity
Status: COMPLETED
Conditions: Blood Pressure
Interventions: DRUG: Regional phenylephrine arterial infusion, Nitric Oxide Clamp
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Outcomes in Patients With Myeloproliferative Neoplasm and Splanchnic Vein Thrombosis
Status: UNKNOWN
Conditions: Myeloproliferative Neoplasm|Splanchnic Vein Thrombosis|Splanchnic Venous Thrombosis|Myeloproliferative Disorders
Interventions: OTHER: standard of care.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: [18F]Florastamin PET/CT Imaging Examination in Patients With Suspected Recurrent or Metastatic Prostate Cancer
Status: RECRUITING
Conditions: High Risk Prostate Carcinoma
Interventions: DRUG: [F-18]Florastamin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Ciprofloxacin Plus Metronidazole Vs Cefixime Plus Metronidazole Therapy for the Treatment of Liver Abscess
Status: UNKNOWN
Conditions: Liver Abscess
Interventions: DRUG: Ciprofloxacin|DRUG: Cefixime
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Visual Outcome and Visual Quality After Bilateral Implantation of the AcrySof® IQ IOL Compared to MI60® and Tecnis® IOL
Status: WITHDRAWN
Conditions: Cataract
Interventions: DEVICE: AcrySof® IQ IOL|DEVICE: Tecnis® Aspheric intraocular lens|DEVICE: Akreos® MI60 intraocular lens
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pembrolizumab in Combination With Decitabine and Hypofractionated Index Lesion Radiation in Pediatrics and Young Adults
Status: COMPLETED
Conditions: Childhood Solid Tumor|Childhood Lymphoma|Relapsed Cancer|Refractory Cancer|Adult Solid Tumor|Adult Lymphoma
Interventions: DRUG: Pembrolizumab|DRUG: Decitabine|RADIATION: Hypofractionated Index Site Radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Congestive Heart Failure Cardiopoietic Regenerative Therapy (CHART-2) Trial - THE CHART-2 TRIAL
Status: UNKNOWN
Conditions: Heart Failure
Interventions: BIOLOGICAL: Experimental|BIOLOGICAL: Sham comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Dosage Adjustment Strategies of Vancomycin in Children
Status: COMPLETED
Conditions: Methicillin-resistant Staphylococcal Infections
Interventions: OTHER: Early vancomycin monitoring and bayesian dosage adjustment|OTHER: usual vancomycin dose and monitoring strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Interest of Ascorbic Acid in the Management of Pneumonia in Elderly People Hospitalized.
Status: COMPLETED
Conditions: Pneumonia With Hospitalized Elderly Patient
Interventions: DRUG: Vitamin C|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Fitness in Allogeneic Stem Cell Transplantation
Status: COMPLETED
Conditions: Hematopoietic Stem Cell Transplantation
Interventions: BEHAVIORAL: Interval Exercise Training/Motivational Accelerometry
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigation of a Novel Cosmeceutical to Reduce the Visible Signs of Cutaneous Aging
Status: UNKNOWN
Conditions: Aging
Interventions: OTHER: Tomorrowlabs cosmeceutical formulation|OTHER: Sham cosmeceutical formulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Safety and Anti-Tumor Activity of Eciskafusp Alfa (RO7284755) Alone or in Combination With Atezolizumab in Participants With Advanced and/or Metastatic Solid Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Solid Tumors
Interventions: DRUG: Eciskafusp Alfa|DRUG: Atezolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I Clinical Trial of Inactivated Rotavirus Vaccine in a Population Aged 6 Weeks-49 Years Old
Status: ACTIVE_NOT_RECRUITING
Conditions: Healthy Volunteers
Interventions: BIOLOGICAL: Inactivated rotavirus vaccine (low dose)|BIOLOGICAL: Inactivated rotavirus vaccine (high dose)|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Phase I, Dose-Escalation Study to Assess the Safety and Biological Activity of Recombinant Human Interleukin-18
Status: COMPLETED
Conditions: Lymphoma, Non-Hodgkin
Interventions: DRUG: SB-485232|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability Study of Flexible Dosing of Brexpiprazole in the Treatment of Subjects With Agitation Associated With Dementia of the Alzheimer's Type
Status: COMPLETED
Conditions: Agitation Associated With|Alzheimer's Disease|Alzheimer's Type|Mental Disorder|Nervous System Diseases
Interventions: DRUG: Brexpiprazole, OPC-34712
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lymphovenous Bypass Manage Venous Leg Ulcers
Status: COMPLETED
Conditions: Venous Leg Ulcer|Lymphovenous Edema
Interventions: PROCEDURE: Lymphovenous bypass, including lymphaticovenular anastomosis/implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cognitive Training for Memory Deficits Associated With Electroconvulsive Therapy
Status: COMPLETED
Conditions: Memory Deficits|Electroconvulsive Therapy
Interventions: BEHAVIORAL: Cognitive Intervention: Memory Training|BEHAVIORAL: Comparable general mental stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nonmyeloablative Hematopoietic Cell Transplantation (HCT) for Patients With Hematologic Malignancies Using Related, HLA-Haploidentical Donors: A Pilot Trial of Peripheral Blood Stem Cells (PBSC) as the Donor Source
Status: COMPLETED
Conditions: Leukemia|MDS|Myelofibrosis|Lymphoma
Interventions: DRUG: Fludarabine|DRUG: Cyclophosphamide|DRUG: Mesna|RADIATION: Total Body Irradiation|OTHER: Hematopoietic stem cell infusion|DRUG: Tacrolimus|DRUG: Mycophenolate|DRUG: G-CSF
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GeneXpert Performance Evaluation for Linkage to Tuberculosis Care
Status: COMPLETED
Conditions: Tuberculosis, Pulmonary|Rifampicin Resistant Tuberculosis
Interventions: DEVICE: GeneXpert I|BEHAVIORAL: Process re-design|OTHER: Performance Feedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Adding a Short Burst of Corticosteroid to the Conventional Treatment of H1 Antihistamines in Emergency Department.
Status: COMPLETED
Conditions: Urticaria|Allergy
Interventions: DRUG: IV Dexamethasone|DRUG: Oral prednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Abdominal Binder After Laparoscopic Cholecystectomy on Enhanced Recovery
Status: COMPLETED
Conditions: Laparoscopy
Interventions: DEVICE: abdomen binder (Sejung Korea, Seoul, Republic of Korea)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Attention Bias Modification Treatment for Major Depressive Disorder in Adolescents
Status: COMPLETED
Conditions: Major Depressive Disorder, Single Episode, Unspecified
Interventions: BEHAVIORAL: ABMT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: External Oblique Intercostal Plane Block for Laparoscopic Sleeve Gastrectomy
Status: COMPLETED
Conditions: Obesity|Analgesia|Postoperative Pain
Interventions: OTHER: Intravenous morphine patient control device|OTHER: External oblique intercostal plane block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: An Investigational Immuno-therapy Study to Evaluate Safety and Effectiveness in Patients With Melanoma That Has Spread to the Brain, Treated With Nivolumab in Combination With Ipilimumab, Followed by Nivolumab by Itself
Status: COMPLETED
Conditions: Melanoma
Interventions: DRUG: Ipilimumab|DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mobile Health and Social Media Physical Activity Intervention Among Adolescent and Young Adult Childhood Cancer Survivors, the StepByStep Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Hematopoietic and Lymphoid Cell Neoplasm|Malignant Solid Neoplasm
Interventions: OTHER: Educational Intervention|DEVICE: FitBit|OTHER: Goal Setting|OTHER: Health Promotion and Education|OTHER: Media Intervention|BEHAVIORAL: Telephone-Based Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety, Tolerability and Immunogenicity of a Third Dose of One of Four Different Formulations of rMenB + MenACWY Combination Vaccine in Adolescents Who Previously Received the Same Study Vaccines
Status: COMPLETED
Conditions: Meningococcal Disease|Meningococcal Meningitis
Interventions: BIOLOGICAL: Meningococcal (groups A, C, W, and Y) oligosaccharide diphtheria CRM-197 conjugate combined with meningococcal (group B) multicomponent recombinant vaccine|BIOLOGICAL: Meningococcal (group B) multicomponent recombinant adsorbed vaccine|BIOLOGICAL: Tdap
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Oocyte Vitrification Aided With Cytochalasin B
Status: COMPLETED
Conditions: Infertility
Interventions: OTHER: Cytochalasin B supplemented vitrification medium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Preoperative Antibiotics for Carpal Tunnel Release Surgery
Status: COMPLETED
Conditions: Carpal Tunnel Syndrome
Interventions: DRUG: Vancomycin|DRUG: Cefazolin|DRUG: Saline Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Phase II Study for Amyloid Binding Imaging Study of [18F]AV-45 in Patients With Mild Cognitive Impairment, Alzheimer's Disease and Healthy Volunteers
Status: UNKNOWN
Conditions: Alzheimer's Disease
Interventions: DRUG: [18F]AV-45 PET amyloid binding imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: High-Sensitivity Cardiac Troponin On Presentation to Rule Out Myocardial Infarction
Status: COMPLETED
Conditions: Acute Coronary Syndrome|Myocardial Infarction
Interventions: OTHER: Validation Phase|OTHER: Randomization Phase|OTHER: Implementation Phase
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Role of K+ and Ca2+ in Development of Muscle Fatigue
Status: COMPLETED
Conditions: Skeletal Muscle Fatigue in Humans
Interventions: DRUG: Terbutaline|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Fed-Fasted, Single and Multiple Ascending Dose Trial of XEN-D0103
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DRUG: 10mg XEN-D0103|DRUG: Placebo|DRUG: 30mg XEN-D0103|DRUG: 60mg XEN-D0103|DRUG: 120mg XEN-D0103|DRUG: 200mg XEN-D0103|DRUG: 150mg XEN-D0103
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Stroke Volume Variation-guided Normovolemic and Restrictive Fluid Management During Craniotomy: a Randomized Controlled Trial
Status: UNKNOWN
Conditions: Supratentorial Neoplasms|Brain Tumor, Primary|Craniotomy
Interventions: DRUG: Intravenous colloid bolus with Voluven
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: GOTHA - The Early Arthritis and Psoriasis Study of Region Västra Götaland, Sweden
Status: ENROLLING_BY_INVITATION
Conditions: Rheumatoid Arthritis|Psoriatic Arthritis|Arthritis|Psoriasis|Cardiovascular Diseases|Obesity|Lung Diseases
Interventions: OTHER: Care as usual
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Mechanical Dilation of the Cervix in a Scarred Uterus
Status: UNKNOWN
Conditions: Pregnancy Related|Labor Complication|Cesarean Section; Dehiscence
Interventions: DEVICE: Cervical balloon|DRUG: Prostaglandins
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Study of the Nonunion of Long Tubular Bone
Status: UNKNOWN
Conditions: Diaphyses
Interventions: DEVICE: Anti-rotational plate|DEVICE: Exchanged Intramedullary nailing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Smartphone Application Based Rehabilitations in Patients With Chronic Respiratory or Cardiovascular Disease
Status: RECRUITING
Conditions: Pulmonary Rehabilitation|Cardiac Rehabilitation
Interventions: DEVICE: smartphone application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Modulation of Immunity-related Gene Expression Under the Chinese Herbal Formula SS-1 Treatment for Sjögren's Syndrome
Status: UNKNOWN
Conditions: Sjögren's Syndrome
Interventions: DRUG: SS-1|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety of Cultured Allogeneic Adult Umbilical Cord Derived Mesenchymal Stem Cell Intravenous Infusion for Lupus
Status: RECRUITING
Conditions: Lupus
Interventions: BIOLOGICAL: AlloRx
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nutrition Support in Pediatric Stem Cell Transplantation
Status: COMPLETED
Conditions: Hematopoietic Stem Cell Transplantation
Interventions: OTHER: parenteral nutrition titrated to measured REE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Assessing Safety and Tolerability of AZD8931 Alone or in Combination With Paclitaxel in Japanese Patients.
Status: COMPLETED
Conditions: Neoplasms|Metastatic Cancer|Breast Cancer
Interventions: DRUG: AZD8931|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of the Trifunctional Antibody Ertumaxomab to Treat Patients With Advanced or Metastatic Breast Cancer
Status: TERMINATED
Conditions: Breast Neoplasms|Breast Cancer
Interventions: DRUG: ertumaxomab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating Tools for Health Promotion and Disease Prevention
Status: COMPLETED
Conditions: Coronary Heart Disease|Stroke|Diabetes|Breast Cancer|Ovarian Cancer|Colorectal Cancer
Interventions: BEHAVIORAL: Familial risk assessment and personalized prevention messages
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: PREVENTION
Clinical trial: Placebo Controlled, Randomized Safety and Efficacy Study of RC-1291 in Cancer Anorexia/Cachexia.
Status: COMPLETED
Conditions: Cancer Cachexia
Interventions: DRUG: RC-1291 HCl|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose:
Clinical trial: Use of GnRHa During Chemotherapy for Fertility Protection
Status: RECRUITING
Conditions: Breast Cancer Female|Acute Leukemia|Lymphoma|Osteosarcoma|Soft Tissue Sarcoma|Ewing Sarcoma
Interventions: DRUG: Triptorelin Embonate|DRUG: Sodium Chloride solution 0.9%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Autogenous Mesenchymal Stem Cell Culture-Derived Signalling Molecules as Enhancers of Bone Formation in Bone Grafting
Status: NOT_YET_RECRUITING
Conditions: Bone Loss, Osteoclastic|Bone Loss, Alveolar|Alveolar Bone Loss|Alveolar Bone Atrophy|Grafting Bone
Interventions: PROCEDURE: Maxillary sinus floor elevation grafting with synthetic bone substitute.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Clinical Trial of SB-509 in Subjects With Diabetic Neuropathy
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1|Diabetes Mellitus, Type 2|Diabetic Polyneuropathy
Interventions: DRUG: SB-509|OTHER: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Low-dose IL-2 in Established T1D - The "PROREG" Study
Status: WITHDRAWN
Conditions: Diabetes Mellitus, Type 1|Diabetes|Diabetes, Autoimmune
Interventions: BIOLOGICAL: ILT-101 (Aldesleukin; IL-2)|OTHER: Treatment-Placebo Arm|OTHER: Placebo Arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Whitening Efficacy and Tooth Sensitivity of Different Concentrations of Hydrogen Peroxide Photoactivated With Violet or Blue LEDs
Status: COMPLETED
Conditions: Color|Bleaching Sensitivity
Interventions: OTHER: 6% hydrogen peroxide gel + violet LED|OTHER: 6% hydrogen peroxide gel + blue LED|OTHER: 35% hydrogen peroxide gel + violet LED|OTHER: 35% hydrogen peroxide gel + blue LED
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Open-Label Long-Term Safety and Efficacy Study of Fixed Dose Combination of Nifedipine Gastrointestinal Therapeutic System and Candesartan Cilexetil in Subjects With Moderate to Severe Essential Hypertension
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Nifedipine GITS/Candesartan Cilexetil FDC(BAY98-7106)|DRUG: Nifedipine GITS/Candesartan Cilexetil FDC(BAY98-7106)|DRUG: Nifedipine GITS/Candesartan Cilexetil FDC(BAY98-7106)|DRUG: Nifedipine GITS/Candesartan Cilexetil FDC(BAY98-7106)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chest dRain rEmoval intrAoperatively afTer thoracOscopic Wedge Resection
Status: COMPLETED
Conditions: Lung Neoplasms|Lung Surgery|Enhanced Recovery After Surgery|Fast-track Surgery|Pain|Opioid Use|Remission
Interventions: PROCEDURE: Intraoperative air leak test|PROCEDURE: Intraoperative chest drain removal|PROCEDURE: Standard chest drain placement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Difference in Central Fatigue During Two Ultra-endurance Practices: Running vs. Cycling
Status: COMPLETED
Conditions: Ultra-marathon Runners
Interventions: OTHER: maximum effort test on a cycloergometer|OTHER: maximum effort test on a treadmill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Bunionectomy Study (0000-063)
Status: COMPLETED
Conditions: Acute Pain
Interventions: DRUG: pregabalin|DRUG: naproxen sodium|DRUG: Comparator: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Tebentafusp in Molecular Relapsed Disease (MRD) Melanoma
Status: RECRUITING
Conditions: Melanoma (Skin)|Melanoma, Uveal
Interventions: DRUG: Tebentafusp
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Role of Opioidergic Systems in Breathing Based Analgesia
Status: COMPLETED
Conditions: Pain
Interventions: BEHAVIORAL: Mindfulness Meditation|BEHAVIORAL: Placebo Meditation|BEHAVIORAL: Slow-Breathing|DRUG: Naloxone|OTHER: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Linear Asymmetric rTMS in Adolescent Treatment-Resistant Depression: Tolerability of Treatment Durations Ranging From Ten Days to One Day
Status: UNKNOWN
Conditions: Treatment Resistant Depression
Interventions: DEVICE: Linear Asymmetric rTMS System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fenzian Asthma Multicenter Outcomes Study
Status: COMPLETED
Conditions: Asthma
Interventions: DEVICE: Fenzian Device|DEVICE: Sham Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Phenylephrine Extended-Release Tablets on Allergy-Related Nasal Congestion (P08498 AM1)
Status: COMPLETED
Conditions: Seasonal Allergic Rhinitis
Interventions: DRUG: Phenylephrine|DRUG: Placebo|DRUG: Loratadine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Multiple Dose Study in Healthy Volunteers to Assess Safety, Pharmacokinetics and Pharmacodynamics of PF 03882845
Status: TERMINATED
Conditions: Healthy Volunteers
Interventions: DRUG: PF 03882845 and Placebo|DRUG: PF 03882845 and Placebo|DRUG: PF 03882845 and Placebo|DRUG: PF 03882845 and Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Neocortical Epilepsies - Do They Progress?
Status: COMPLETED
Conditions: Epilepsy
Interventions: DEVICE: Arm 1: Juvenile Myoclonic Epilepsy|DEVICE: Arm 2: Frontal Lobe Epilepsy|DEVICE: Arm 3: Normal Controls
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Assessment of the Quality of Sleep and Sleep Disorders Among the Professional and Volunteer Firefighters of Loire
Status: COMPLETED
Conditions: Firefighter
Interventions: DIAGNOSTIC_TEST: socio-demographic data and personal medical history|DIAGNOSTIC_TEST: Pittsburgh Sleep Quality Index (PSQI)|DIAGNOSTIC_TEST: Epworth Sleepiness Scale|DIAGNOSTIC_TEST: Insomnia Severity Index (ISI)|DIAGNOSTIC_TEST: stop-BANG questionnaire
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Bond Apatite in Horizontal Augmentation Versus Bio-Oss
Status: COMPLETED
Conditions: Horizontal Ridge Deficiency
Interventions: OTHER: Bond Apatite|OTHER: Bio-Oss
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Shared Decision Making for Antipsychotic Medications
Status: NOT_YET_RECRUITING
Conditions: Schizophrenia|Schizoaffective Disorder|Schizophreniform Disorders|Delusional Disorder|Other Specified Schizophrenia Spectrum and Other Psychotic Disorder
Interventions: OTHER: The Antipsychotic Medication Decision Aid (APM-DA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: STABILITY: Physical Activity Intervention at 7 Years Post-Anterior Cruciate Ligament Reconstruction
Status: RECRUITING
Conditions: Anterior Cruciate Ligament Reconstruction|Post-traumatic Osteoarthritis
Interventions: DEVICE: PARx
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effect of Vitamin D on Fertility
Status: COMPLETED
Conditions: Infertility|Infertility, Female|Vitamin D Deficiency|Vitamin D3 Deficiency
Interventions: DRUG: DEVIT-3
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Nutritional Supplements in Improving Quality of Life During First-Line Chemotherapy in Patients With Metastatic Gynecological Cancer
Status: UNKNOWN
Conditions: Cervical Cancer|Endometrial Cancer|Fallopian Tube Cancer|Ovarian Cancer|Sarcoma|Vaginal Cancer|Vulvar Cancer
Interventions: DIETARY_SUPPLEMENT: therapeutic nutritional supplementation|PROCEDURE: standard follow-up care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Valproic Acid in Treating Young Patients With Recurrent or Refractory Solid Tumors or CNS Tumors
Status: COMPLETED
Conditions: Brain and Central Nervous System Tumors|Unspecified Childhood Solid Tumor, Protocol Specific
Interventions: DRUG: valproic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: TATE Versus TACE in Intermediate Stage HCC
Status: SUSPENDED
Conditions: Carcinoma, Hepatocellular
Interventions: DRUG: Tirapazamine|DRUG: Doxorubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT