pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Randomized Controlled Study Comparing Three Single-incision Devices for Female Urinary Stress Incontinence
Status: COMPLETED
Conditions: Urinary Incontinence
Interventions: PROCEDURE: MiniArc positioning|PROCEDURE: TVT secur system positioning|PROCEDURE: Ajust positioning|PROCEDURE: Tension free vaginal ttape
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: This Study Will Describe the Burden of DENgue Fever Virus (DENV) Illness Among Household Members Aged 6 Months to 50 Years of Selected Communities in Latin America and Southeast Asia
Status: TERMINATED
Conditions: Dengue|Dengue Vaccines
Interventions: PROCEDURE: Blood sample collection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Pericapsular Nerve Group (PENG) Block Versus Lumbar Erector Spinae Plane Block
Status: COMPLETED
Conditions: Pericapsular Nerve Group Block (PENG Block)|Lumbar Erector Spinae Plane Block
Interventions: PROCEDURE: Pericapsular Nerve Block|PROCEDURE: Lumbar Erector Spinae Plane Block|DRUG: Fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: SIRT With Tremelimumab and Durvalumab for Resectable HCC
Status: RECRUITING
Conditions: Resectable Hepatocellular Carcinoma|Hepatocellular Carcinoma|Hepatocellular Cancer
Interventions: DRUG: Durvalumab|DRUG: Tremelimumab|DEVICE: SIRT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Surgery, Radiation Therapy, and Chemotherapy With or Without Photodynamic Therapy in Treating Patients With Newly Diagnosed or Recurrent Malignant Supratentorial Gliomas
Status: UNKNOWN
Conditions: Brain and Central Nervous System Tumors
Interventions: DRUG: carmustine|DRUG: lomustine|DRUG: porfimer sodium|DRUG: procarbazine hydrochloride|PROCEDURE: neoadjuvant therapy|PROCEDURE: surgical procedure|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Acalabrutinib, Lenalidomide, and Rituximab for the Treatment of CD20 Positive Stage III-IV, Grade 1-3a Follicular Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Ann Arbor Stage III Grade 1 Follicular Lymphoma|Ann Arbor Stage III Grade 2 Follicular Lymphoma|Ann Arbor Stage III Grade 3 Follicular Lymphoma|Ann Arbor Stage IV Grade 1 Follicular Lymphoma|Ann Arbor Stage IV Grade 2 Follicular Lymphoma|Ann Arbor Stage IV Grade 3 Follicular Lymphoma|Grade 3a Follicular Lymphoma
Interventions: DRUG: Acalabrutinib|DRUG: Lenalidomide|BIOLOGICAL: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of the Effect of Iron Fortified Rice in Iron Deficient Anemic Women
Status: COMPLETED
Conditions: Iron Deficiency Anemia
Interventions: OTHER: Non-fortified rice|OTHER: Iron-fortified Rice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: SCI-110 in the Treatment of Tourette Syndrome
Status: NOT_YET_RECRUITING
Conditions: Tourette Syndrome
Interventions: DRUG: SCI-110|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Nitrous Oxide for Pain Alleviation in Women Undergoing Osmotic Dilator Insertion for Dilatation and Evacuation
Status: NOT_YET_RECRUITING
Conditions: Pain Alleviation|Dilatation and Evacuation|Laminaria Placement|Nitrous Oxide
Interventions: DRUG: Nitrous oxide (N2O/O2)|DRUG: Oxygen (O2)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Prevention of Delirium and Complications Associated With Surgical Treatments Multi Center Clinical Trial
Status: COMPLETED
Conditions: Delirium
Interventions: DRUG: Ketamine (0.5 mg/kg)|DRUG: Normal Saline (placebo)|DRUG: Ketamine (1 mg/kg)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: UPDRS-III Comparisons of DBS for PD Between Patients Receiving MAC and AAA Anesthesia
Status: COMPLETED
Conditions: Parkinson Disease|Anesthesia
Interventions: PROCEDURE: MAC anesthesia|PROCEDURE: AAA anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Pharmacokinetics and Pharmacodynamics Study of LBS-008 in Healthy Volunteers Aged 50-85
Status: COMPLETED
Conditions: Healthy Volunteer|Dry Age-related Macular Degeneration
Interventions: DRUG: Tinlarebant (LBS-008)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Berberine as Adjuvant Treatment for Schizophrenia Patients
Status: COMPLETED
Conditions: Schizophrenia|Schizophrenia Spectrum and Other Psychotic Disorders|Metabolic Syndrome x
Interventions: DRUG: Berberine|DRUG: Placebos|DRUG: Antipsychotic Agents
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Evaluate the Antihypertensive Efficacy and Changes of Neurohormonal Markers of Fimasartan and Atenolol With Exaggerated Blood Pressure Response During Exercise in Essential Hypertensive Patients
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Fimasartan|DRUG: Atenolol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Zinc-L-Carnosine Prevents Dysphagia in Breast Cancer Patients Undergoing Adjuvant Radiotherapy
Status: COMPLETED
Conditions: Breast Cancer Female|Dysphagia|Adjuvant Radiotherapy
Interventions: DEVICE: Hepilor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effects of Repetitive Transcranial Magnetic Stimulation on Pain Thresholds in Patients With Chronic Low Back Pain
Status: UNKNOWN
Conditions: Low Back Pain
Interventions: PROCEDURE: repetitive transcranial magnetic stimulation (rTMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pantoprazole Sodium 40 mg DR Tablets Under Fasting Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Pantoprazole Sodium 40 mg delayed-release tablets|DRUG: PROTONIX® 40 mg delayed-release tablets.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Comparative Analysis of the Microcirculation During Cardiac Surgery With Minimal Invasive Versus Conventional Extracorporeal Circulation
Status: COMPLETED
Conditions: Coronary Artery Disease|Aortic Valve Stenosis|Mitral Disease
Interventions: DEVICE: Cerebral oximetry|DEVICE: Peripheral oximetry|DEVICE: Cerebral autoregulation|DEVICE: Sublingual microscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: DIAGNOSTIC
Clinical trial: EKSO Trial: Powered Exoskeleton for Ambulation in Subjects With Spinal Cord Injury (SCI)
Status: ACTIVE_NOT_RECRUITING
Conditions: Spinal Cord Injuries or Similar Neurological Weakness
Interventions: DEVICE: Ekso exoskeleton
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Follow-up Study to Assess One Boost Immunization With AFFITOPE® PD01A With Regard to Safety and Clinical Activity
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: BIOLOGICAL: AFFITOPE® PD01A|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Gaviscon-Advance® in Suppressing Post-supper Acid-pocket and Night-time Acid-reflux in Obese Participants
Status: COMPLETED
Conditions: Gastroesophageal Reflux Disease|Acid Reflux|Obesity
Interventions: DRUG: Alginate-antacid group|DRUG: Non antacid alginate group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antidepressant and Antipsychotic to Treat Attenuated Positive and Negative Symptoms
Status: COMPLETED
Conditions: Prodromal Schizophrenia|Psychotic Disorders
Interventions: DRUG: risperidone|DRUG: sertraline-primary
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Cryotherapy for Barrett's Esophagus and Early Esophageal Cancers
Status: COMPLETED
Conditions: Barretts Esophagus|Esophageal Cancer
Interventions: PROCEDURE: Cryospray Ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chest Lymph Node Sampling in Patients With Advanced Lung Cancer to be Treated With Curative-intent Radiation Treatment
Status: RECRUITING
Conditions: Non-Small Cell Lung Cancer
Interventions: PROCEDURE: Endobronchial ultrasound-guided transbronchial fine needle aspiration (EBUS-TFNA)|PROCEDURE: Transesophageal ultrasound-guided fine needle aspiration (EUS-FNA)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Post Approval Study to Assure the ContInued saFety and effectIveness of Neuro Cochlear Implant System in Adult Users
Status: NOT_YET_RECRUITING
Conditions: Sensorineural Hearing Loss, Bilateral|Sensorineural Hearing Loss, Severe|Sensorineural Hearing Loss, Profound
Interventions: DEVICE: Neuro Cochlear Implant system
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Salt Water Nebulization on Cough, Sputum and Quality of Life in Chronic Obstructive Pulmonary Patients
Status: COMPLETED
Conditions: Copd
Interventions: OTHER: Nebulization application with 5 ml isotonic sodium chloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of CTX-471 as a Monotherapy or in Combination With Pembrolizumab in Patients Post PD-1/PD-L1 Inhibitors in Metastatic or Locally Advanced Malignancies
Status: ACTIVE_NOT_RECRUITING
Conditions: Locally Advanced Solid Tumor|Metastatic Cancer|Non-small Cell Lung Cancer|Small Cell Lung Cancer|Mesothelioma|Melanoma|Head and Neck Cancer
Interventions: DRUG: CTX-471|DRUG: Pembrolizumab (KEYTRUDA®)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study To Evaluate Pharmacokinetics, Efficacy, Safety, Tolerability, And Pharmacodynamics Of Satralizumab In Pediatric Patients With Aquaporin-4 Antibody Positive Neuromyelitis Optica Spectrum Disorder (NMOSD)
Status: RECRUITING
Conditions: Neuromyelitis Optica Spectrum Disorder|NMOSD
Interventions: DRUG: Satralizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intestinal Microflora in Colorectal Cancer (CRC) After Chemotherapy
Status: UNKNOWN
Conditions: Gastrointestinal Neoplasms|Colorectal Cancer|Effects of Chemotherapy|Tumor Immunity|Malnutrition
Interventions: DRUG: Probiotic|DRUG: placebo（for probiotic）
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Dexmedetomidine on the Liver Injury After Hepatectomy
Status: COMPLETED
Conditions: Ischemia-reperfusion Injury
Interventions: DRUG: dexmedetomidine|DRUG: 0.9% sodium chloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Randomised Controlled Trial of a Multi-faceted Community-based Intervention to Improve Asthma in Children
Status: COMPLETED
Conditions: Asthma
Interventions: PROCEDURE: asthma control awareness|PROCEDURE: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: NORTHERA (DROXIDOPA) for Dysautonomia in Adult Survivors of Menkes Disease and Occipital Horn Syndrome
Status: RECRUITING
Conditions: Menkes Disease|Occipital Horn Syndrome
Interventions: DRUG: Droxidopa|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of Kinesio Taping to Treat Muscular and Joint Problems in Chronic Venous Insufficiency
Status: COMPLETED
Conditions: Chronic Venous Insufficiency
Interventions: OTHER: Kinesio Taping|OTHER: Placebo kinesio taping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Necitumumab in the First-Line Treatment of Stage IV Squamous Non-Small Cell Lung Cancer (NSCLC)
Status: COMPLETED
Conditions: Squamous Non-small Cell Lung Cancer
Interventions: DRUG: Necitumumab|DRUG: Gemcitabine|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Zinc Supplementation on Very Low Birth Weight Infant
Status: UNKNOWN
Conditions: Early-Onset Sepses, Neonatal|Periventricular Haemorrhage Neonatal|Bronchopulmonary Dysplasia|Retinopathy of Prematurity|Enterocolitis, Necrotizing|Small for Gestational Age Infant
Interventions: DRUG: Zinc Sulfate|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Effectiveness and Safety of Prolonged Release OROS Methylphenidate in Adults With Attention Deficit Hyperactivity Disorder
Status: COMPLETED
Conditions: Attention Deficit/ Hyperactivity Disorder
Interventions: DRUG: prolonged release (PR) OROS methylphenidate 54 mg|DRUG: prolonged release (PR) OROS methylphenidate 72 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Effectiveness of Three Lucid Dreaming and Sleep Hygiene Techniques
Status: COMPLETED
Conditions: Anxiety
Interventions: BEHAVIORAL: Lucid Dream|BEHAVIORAL: Stress Reduction|BEHAVIORAL: Sleep Hygiene Techniques
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Exploration of Differences in Metabolite Concentrations by NMR Spectroscopy in the Ventral Striatum, Anterior Cingulate Cortex and Prefrontal Cortex in Euthymic Patients With Unipolar and Bipolar Type II Mood Disorders, as Well as in Healthy Subjects
Status: RECRUITING
Conditions: Bipolar Disorder Type II|Mood Depressive Disorder
Interventions: DIAGNOSTIC_TEST: NMR spectrometry
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Pragmatic Study to Investigate the Efficacy and Safety of Mepolizumab in Severe Uncontrolled Asthma in Brazil
Status: UNKNOWN
Conditions: Eosinophilic Asthma
Interventions: DRUG: Mepolizumab 100 MG [Nucala]
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Magnesium Sulfate Dose in Obese Patients.
Status: COMPLETED
Conditions: Magnesium Sulfate|Postoperative Pain|Obesity
Interventions: DRUG: Magnesium sulfate through real weight group|DRUG: Placebo group|DRUG: Magnesium sulfate through ideal corrected weight group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of AVE5026 as Compared to Enoxaparin for the Prevention of Venous Thromboembolism in Patients Undergoing Major Abdominal Surgery
Status: COMPLETED
Conditions: Venous Thromboembolism
Interventions: DRUG: Semuloparin Sodium|DRUG: Enoxaparin sodium|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Trial to Evaluate the Efficacy of a Manualized Reflective Writing Program for Clinical Phase Physician Assistant (PA) Students.
Status: SUSPENDED
Conditions: Burn Out|Student Burnout|Physician Assistant Student Burnout
Interventions: BEHAVIORAL: Reflective Writing Workshop Sessions
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Wide Frequency Band Test of Hearing in Veterans
Status: COMPLETED
Conditions: Hearing Loss, Sensorineural|Hearing Loss, Conductive|Hearing Loss, Mixed Conductive-Sensorineural|Otosclerosis|Tympanic Membrane Perforation|Otitis Media With Effusion|Cholesteatoma
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Congestive Heart Failure Pilot Study Utilizing Wireless Home Scale and Daily Symptom Monitoring
Status: COMPLETED
Conditions: Congestive Heart Failure
Interventions: BEHAVIORAL: Daily weight measured by digital scale and symptom reporting
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Occupational Self-Analysis Programme
Status: COMPLETED
Conditions: Occupational Therapy|Intellectual Disability|Acquired Brain Injury|Students|Stroke|Awareness
Interventions: BEHAVIORAL: Occupational self-analysis|BEHAVIORAL: Vocational guidance|BEHAVIORAL: Usual Rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Somatostatin Receptor Imaging in Patients With Suspected Cardiac Sarcoidosis
Status: COMPLETED
Conditions: Sarcoidosis
Interventions: DRUG: Indium-111 Pentreotide|DRUG: Gallium-68 DOTATATE
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: tDCS as an add-on Treatment in SSRI-resistant OCD
Status: UNKNOWN
Conditions: Obsessive-Compulsive Disorder
Interventions: DEVICE: transcranial dirrect current stimulation|DEVICE: Sham tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Oral Alfacalcidol and Coronary Artery Calcification in Predialysis Chronic Kidney Disease
Status: UNKNOWN
Conditions: Vascular Calcification
Interventions: DRUG: oral alfacalcidol|DRUG: no drug
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Postoperative Prevention and Treatment of Median Sternotomy Scars With Botulinum Toxin Type A Injection
Status: COMPLETED
Conditions: Scar
Interventions: DRUG: Botulinum toxin type A|DRUG: normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: 68Ga-PSMA-Dual-Contrast PET/MRI or PET/CT for Early Detection of Liver Cancer
Status: RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: PROCEDURE: Computed Tomography|DRUG: Gallium Ga 68 Gozetotide|PROCEDURE: Magnetic Resonance Imaging|PROCEDURE: Positron Emission Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Combination Chemotherapy With or Without Trastuzumab in Treating Women With Metastatic Breast Cancer
Status: COMPLETED
Conditions: Recurrent Breast Cancer|Stage IV Breast Cancer
Interventions: DRUG: pegylated liposomal doxorubicin hydrochloride|DRUG: docetaxel|BIOLOGICAL: trastuzumab|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating an Online Wellness Intervention for Indian College Students
Status: COMPLETED
Conditions: Depressive Symptoms|Anxiety|Happiness
Interventions: BEHAVIORAL: Common Elements Toolbox|BEHAVIORAL: Wait-list control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Adductor Canal Block: Continuous Infusion Versus Automatic Intermittent Bolus
Status: COMPLETED
Conditions: Injury of Anterior Cruciate Ligament
Interventions: PROCEDURE: Continuous Infusion of ropivacaine 0.2%|PROCEDURE: Automatic Intermittent Bolus of ropivacaine 0.2%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Tolerance and Efficacy of Pembrolizumab or Cetuximab Combined With RT in Patients With Locally Advanced HNSCC
Status: COMPLETED
Conditions: Squamous Cell Carcinoma of the Head and Neck
Interventions: DRUG: Pembrolizumab|DRUG: Cetuximab|RADIATION: Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sequential CAR-T Cells Targeting BCMA/CD19 in Patients With Relapsed/ Refractory Autoimmune Diseases
Status: RECRUITING
Conditions: Autoimmune Diseases|Systemic Lupus Erythematosus|Systemic Lupus Erythematosus Acute|Sjogren's Syndrome
Interventions: BIOLOGICAL: BCMA/CD19 CAR-T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Computerized Cognitive Training in Persons With MS
Status: COMPLETED
Conditions: Multiple Sclerosis, Relapsing-Remitting
Interventions: DEVICE: BrainHQ cognitive training|DEVICE: BrainHQ control games
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: PET/CT (Positron Emission Tomography / Computed Tomography) Investigations With BAY86-9596 (18F) (300 MBq) Following Single Intravenous Administration in Patients With Cancer or Inflammations.
Status: COMPLETED
Conditions: Diagnostic Imaging
Interventions: DRUG: BAY86-9596
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Phase I/IIa Open-Label, Dose Escalation and Cohort Expansion Trial of Oral TSR-011 in Patients With Advanced Solid Tumors and Lymphomas
Status: COMPLETED
Conditions: Solid Tumors|Lymphomas
Interventions: DRUG: TSR-011
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cryoplasty CLIMB-registry
Status: COMPLETED
Conditions: Critical Limb Ischemia|Peripheral Arterial Occlusive Disease
Interventions: DEVICE: PolarCath Peripheral Dilatation System (Boston Scientific)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial in Subjects Suspected to Have Tuberculosis, Comparing the Diagnostic Performance of C-Tb to QuantiFERON®, in Combination With a Safety Assessment of C-Tb Versus Tuberculin PPD RT23 SSI
Status: COMPLETED
Conditions: Tuberculosis
Interventions: BIOLOGICAL: C-Tb|BIOLOGICAL: 2 T.U. Tuberculin PPD RT 23 SSI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Randomized Clinical Trial With Aminocaproic Acid in the Prevention of Exodontic Bleeding in Anticoagulants Patients
Status: UNKNOWN
Conditions: Oral Hemorrhage
Interventions: DRUG: Aminocaproic acid|OTHER: Routine dental care|DRUG: lidocaine and epinephrine|DRUG: Paracetamol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Phase IV Study of the Impact of Dietary Fibers on Symptoms and Esophageal Motility in Patients With Non-erosive GERD
Status: COMPLETED
Conditions: Gastroesophageal Reflux Disease
Interventions: DRUG: Mucofalk
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Toolkit to Improve Cardiovascular Disease Screening and Treatment for People With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus|Cardiovascular Disease
Interventions: OTHER: Toolkit|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Individualized Cognitive Training in HIV
Status: COMPLETED
Conditions: HIV-Associated Cognitive Motor Complex|Aging|Cognitive Impairment|Cognitive Decline|Attention Impaired|Processing, Visual Spatial|Cognitive Deficit in Attention|Cognitive Disorder in Remission
Interventions: BEHAVIORAL: Individualized Cognitive Training|OTHER: No-Contact Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I Clinical Study: BG1805 Injection in the Treatment of Relapsed or Refractory Acute Myeloid Leukemia
Status: RECRUITING
Conditions: Leukemia, Myeloid, Acute
Interventions: BIOLOGICAL: BG1805
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessing the Preventing and Therapeutic Effect of Propolis in Radiotherapy Induced Mucositis of Head and Neck Cancers
Status: COMPLETED
Conditions: Radiation-induced Mucositis of Oral Mucous Membranes
Interventions: DRUG: propolis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Interaction of Apelin and Angiotensin in the Human Forearm Circulation
Status: COMPLETED
Conditions: Heart Disease|Vasodilation
Interventions: DRUG: Apelin infusion|DRUG: Sodium nitroprusside infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Two Bilateral Metal Stenting in Hilar Malignancy
Status: UNKNOWN
Conditions: Malignant Hilar Stricture|Bilateral Stent Insertion
Interventions: PROCEDURE: Bilateral stent-in-stent insertion|PROCEDURE: Bilateral side-by-side insertion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Pharmacokinetic(PK) Study of GW003 to Metastatic Tumors
Status: COMPLETED
Conditions: Chemotherapy-induced Neutropenia|Metastatic Tumors
Interventions: BIOLOGICAL: GW003
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radiofrequency Balloon Ablation for Atrial Fibrillation: Durability of Pulmonary Vein Isolated and Clinical Outome
Status: ACTIVE_NOT_RECRUITING
Conditions: Atrial Fibrillation
Interventions: PROCEDURE: Radiofrequency balloon catheter ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Nivolumab Alone or Nivolumab Combination Therapy in Colon Cancer That Has Come Back or Has Spread
Status: ACTIVE_NOT_RECRUITING
Conditions: Microsatellite Unstable Colorectal Cancer|Microsatellite Stable Colorectal Cancer|Mismatch Repair Proficient Colorectal Cancer|Mismatch Repair Deficient Colorectal Cancer
Interventions: DRUG: Ipilimumab|DRUG: Nivolumab|DRUG: Cobimetinib|DRUG: Daratumumab|DRUG: BMS-986016
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Ultrashort PRS Regimen V in the Treatment of MDR-TB
Status: RECRUITING
Conditions: MDR-TB
Interventions: DRUG: PRS Regimen V|DRUG: MDR-TB Treatment Regimen(WHO)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Role of the Posterior Parietal Cortex in the Processing of Sensory Information
Status: UNKNOWN
Conditions: Healthy Subject
Interventions: DEVICE: Transcranial Magnetic Stimulation (TMS)|DEVICE: Electrical Muscle Activity (EMG)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Multilevel Approach for Improvement in Screening of Colorectal Cancer in Rural Communities, The Screen to Save Trial
Status: TERMINATED
Conditions: Colorectal Carcinoma
Interventions: OTHER: Educational Intervention|OTHER: Fecal Immunochemical Test|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: SWAP-MEAT: Study With Appetizing Plant Food - Meat Eating Alternatives Trial
Status: COMPLETED
Conditions: Microbiome|Immune Function|Cardiovascular Diseases
Interventions: BEHAVIORAL: Meat products|BEHAVIORAL: Plant Alternative products
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Erector Spina Plane Block vs Serratus Anterior Plane Block for Postoperative Mastectomy Pain
Status: UNKNOWN
Conditions: Mastectomy|Pain, Postoperative|Recovery Period, Anesthesia
Interventions: PROCEDURE: serratus anterior plane block|PROCEDURE: erector spina plane block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Preventing Sensory and Motor Dysfunctions in Children Receiving Neurotoxic Chemotherapy
Status: RECRUITING
Conditions: Chemotherapy-induced Peripheral Neuropathy|Pediatric Cancer
Interventions: BEHAVIORAL: Playful sensorimotor training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Vaccination With Autologous Dendritic Cells Loaded With Autologous Tumour Homogenate in Glioblastoma
Status: RECRUITING
Conditions: Glioblastoma|Vaccination
Interventions: BIOLOGICAL: Autologous Dendritic Cells (DC) vaccine|DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Meloxicam Capsules to Treat Osteoarthritis Pain
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DRUG: Meloxicam Test Capsules|DRUG: Meloxicam Test Capsules|DRUG: Placebo Capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tobacco, Alcohol, Prescription Drug, and Illicit Substance Use- Electronic Spanish Platform
Status: ENROLLING_BY_INVITATION
Conditions: Tobacco Use|Alcohol Abuse|Prescription Drug Abuse|Substance Use
Interventions: OTHER: Screening
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Safety and Immunogenicity of Venezuelan Equine Encephalomyelitis Vaccine (VEE C-84) as a Booster to VEE TC-83
Status: UNKNOWN
Conditions: Venezuelan Equine Encephalomyelitis
Interventions: BIOLOGICAL: VEE C-84
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Informativeness to Digital Rectal Examination
Status: COMPLETED
Conditions: Colon Cancer|Upper Rectum Cancer|Diverticulitis|Rectal Bleeding|Hernia
Interventions: PROCEDURE: lateral decubitus|PROCEDURE: supine decubitus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Occurrence of Ventilator Associated Pneumonia in Italian ICU Using Cuffed Tracheostomy Tubes With Subglottic Secretion Drainage
Status: COMPLETED
Conditions: Respiratory Failure
Interventions: PROCEDURE: subglottic secretion removal
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Noninvasive Cardiac Radioablation for Ventricular Tachycardia Refractory to Medication and Catheter Ablation
Status: WITHDRAWN
Conditions: Ventricular Tachycardia
Interventions: RADIATION: Cardiac radioablation (CRA)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of the Ultrasound-guided Approach on the Efficiency and Safety of the Stellate Ganglion Block in Chronic Pain
Status: TERMINATED
Conditions: Complex Regional Pain Syndromes
Interventions: PROCEDURE: Blind technique|PROCEDURE: Ultrasound-guided technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Satiety Response of Short Chain Fructooligosaccharide
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Short chain fructo-oligosaccharide (scFOS) 5 g|OTHER: Placebo|DIETARY_SUPPLEMENT: Short chain fructooligosaccharide (scFOS) 8 g
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of Canagliflozin in Study Participants With Various Degrees of Impaired Hepatic (Liver) Function
Status: COMPLETED
Conditions: Healthy|Hepatic Insufficiency
Interventions: DRUG: Canagliflozin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: The Hypoalgesic Effects of BFR Training in Nonspecific Shoulder Pain.
Status: ACTIVE_NOT_RECRUITING
Conditions: Shoulder Pain|BFR|Shoulder Impingement
Interventions: DEVICE: Blood flow restriction (BFR) with low load resistance training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: DLBS1033 Treatment in Diabetic With Peripheral Arterial Disease
Status: TERMINATED
Conditions: Diabetes|Peripheral Arterial Disease
Interventions: DRUG: DLBS1033|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of a Combination of Telmisartan/S-Amlodipine Compared With Telmisartan Monotherapy
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Telminuvo®Tab. 40/2.5mg|DRUG: Telmitrend®Tab. 80mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing the Effects of Cognitive Training and Physical Exercise on Cognition, Cerebral Autoregulation and Cerebral Vasoreactivity in Men and Women With Heart Failure
Status: RECRUITING
Conditions: Chronic Heart Failure|Aging
Interventions: OTHER: Cognitive training|OTHER: Exercise training|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study in Healthy Volunteers to Assess Safety and Blood Levels of AZD9742 After Multiple Doses Over 14 Days
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: AZD9742|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of BE1116 in Patients With Traumatic Injury and Acute Major Bleeding to Improve Survival ( TAP Study )
Status: RECRUITING
Conditions: Traumatic Injury
Interventions: DRUG: BE1116|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rituximab in Pretreated Elderly or Unfit B-CLL Patients
Status: COMPLETED
Conditions: B-Cell Chronic Lymphocytic Leukemia
Interventions: DRUG: Rituximab|DRUG: Glucocorticoid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Subcutaneous Bupivacaine Decrease Post-op Pain in Patients Undergoing C-Section
Status: TERMINATED
Conditions: Pain, Referred
Interventions: DRUG: Bupivacaine|DRUG: Morphine|DRUG: Fentanyl|DRUG: Epinephrine|OTHER: Saline solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Preventing Recurrent Vascular Events in Patients With Stroke or Transient Ischemic Attack
Status: COMPLETED
Conditions: Ischemic Stroke|Transient Ischemic Attacks
Interventions: DRUG: Antihypertensive agents and lipid lowering therapy|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy of Repeated Intravitreal Administration of Vascular Endothelial Growth Factor (VEGF) Trap in Patients With Wet Age-Related Macular Degeneration (AMD)
Status: COMPLETED
Conditions: Macular Degeneration
Interventions: BIOLOGICAL: aflibercept injection (VEGF Trap-Eye, BAY86-5321)|BIOLOGICAL: aflibercept injection (VEGF Trap-Eye, BAY86-5321)|BIOLOGICAL: aflibercept injection (VEGF Trap-Eye, BAY86-5321)|BIOLOGICAL: aflibercept injection (VEGF Trap-Eye, BAY86-5321)|BIOLOGICAL: aflibercept injection (VEGF Trap-Eye, BAY86-5321)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Aerosol and Droplet Dispersion During Gastrointestinal Motility Investigations
Status: COMPLETED
Conditions: Aerosol Generation and Droplet Dispersion and Deposition During Naso-gastric Intubation for Gastrointestinal Motility Investigations
Interventions: OTHER: Fluorescein|OTHER: Particle measurement
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Bicycle Training on Ventilatory Functions in Duchenne Muscular Dystrophy
Status: NOT_YET_RECRUITING
Conditions: Duchenne Muscular Dystrophy
Interventions: OTHER: Designed Physical Therapy Program|OTHER: Bicycle Ergometry Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of an H1 Receptor Antagonist on Exercise Performance in Hypoxia
Status: COMPLETED
Conditions: Hypoxia, Altitude
Interventions: DRUG: Cetirizine|DRUG: Placebo oral capsule|OTHER: Hypoxia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Trial of Mepolizumab Adjunctive Therapy for the Prevention of Asthma Exacerbations in Urban Children
Status: COMPLETED
Conditions: Asthma
Interventions: BIOLOGICAL: Mepolizumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Pharmacokinetic Study of MK-3102 in Participants With Impaired Hepatic Function (MK-3102-031)
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: MK-3102
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ShigETEC Vaccine Study in Bangladesh
Status: RECRUITING
Conditions: Healthy Volunteers
Interventions: BIOLOGICAL: ShigETEC live, attenuated, oral vaccine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Investigating the Safety and Performance of Two New 1-piece Ostomy Products Compared With SenSura 1-piece
Status: COMPLETED
Conditions: Ileostomy - Stoma
Interventions: DEVICE: Coloplast Test Product 1|DEVICE: Coloplast Test Product 2|DEVICE: Coloplast SenSura
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Phase I/II Study of KDX-0811(Dexrazoxane) in the Treatment of Accidental Extravasation of Anthracycline Anti-cancer Agents
Status: COMPLETED
Conditions: Extravasations of Anthracycline Anti-cancer Agents
Interventions: DRUG: Dexrazoxane
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cognitive Effects of Adjuvant Vortioxetine in Early Schizophrenia
Status: RECRUITING
Conditions: Cognitive Impairment With Primary Psychotic Disorder|Negative Symptoms With Primary Psychotic Disorder
Interventions: DRUG: Vortioxetine|DRUG: Usual Antipsychotic Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasound Versus Fluoroscopic Guided Sacroiliac Joint Injection In Patients With Chronic Sacroiliac Joint Pain
Status: COMPLETED
Conditions: Sacro-Iliac Spondylosis
Interventions: DEVICE: Sacroiliac joint injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impaired Risk Awareness During Intoxication in DUI Offenders
Status: RECRUITING
Conditions: Alcohol Use
Interventions: BEHAVIORAL: Blood alcohol concentration (BAC) discrimination training|BEHAVIORAL: Performance feedback training|BEHAVIORAL: Blood alcohol concentration (BAC) discrimination training for controls
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Phase 2, Multicenter, Randomized, Double-Blind, Vehicle Controlled, Parallel-Group, Clinical Study in the Treatment of Acne Vulgaris
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: IDP-126 Gel|DRUG: IDP-126 Component A|DRUG: IDP-126 Component B|DRUG: IDP-126 Component C|DRUG: IDP-126 Vehicle Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Shock Wave Therapy Versus Low Level Laser Therapy in Patients With Plantar Fasciitis
Status: COMPLETED
Conditions: Plantar Fascitis
Interventions: OTHER: conventional therapy|OTHER: shock wave therapy|OTHER: low level laser therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Blood-brain Barrier Permeability Study in Adults With Meningitis
Status: TERMINATED
Conditions: Blood-Brain Barrier Permeability
Interventions: OTHER: ICG-PULSION|DEVICE: LiMON, Pulsion Medical Systems|OTHER: Gadolinium (Gadovist, Bayer, Germany)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Unilateral TAP Block for Laparoscopic Gastric Sleeve Surgery
Status: COMPLETED
Conditions: Laparoscopic Sleeve Gastrectomy|Subcostal Transversus Abdominis Plane Block
Interventions: DRUG: Saline|DRUG: Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Study to Evaluate the Safety and Efficacy of Aceneuramic Acid Extended-Release (Ace-ER) Tablets in Patients With Glucosamine (UDP-N-acetyl)-2-epimerase Myopathy (GNEM) or Hereditary Inclusion Body Myopathy (HIBM)
Status: TERMINATED
Conditions: Hereditary Inclusion Body Myopathy|Distal Myopathy With Rimmed Vacuoles|Distal Myopathy, Nonaka Type|GNE Myopathy|Quadriceps Sparing Myopathy
Interventions: DRUG: Aceneuramic Acid Extended-Release Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial to Compare the Ovarian Response of REKOVELLE and GONAL-F in Conventional Dosing in Women Undergoing Controlled Ovarian Stimulation
Status: COMPLETED
Conditions: Infertility
Interventions: DRUG: REKOVELLE (Follitropin Delta)|OTHER: GONAL-F (Follitropin Alfa)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A National School-based Health Lifestyles Interventions Among Chinese Children and Adolescents Against Obesity
Status: COMPLETED
Conditions: Pediatric Obesity
Interventions: BEHAVIORAL: The Health Lifestyles Interventions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION