pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Effects of Reiki on Stress
Status: COMPLETED
Conditions: Stress
Interventions: OTHER: Rest|OTHER: Sham|OTHER: Reiki
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Compare Safety and Immunogenicity of Commercial Scale Consistency Lots of Herpes Simplex Vaccine
Status: COMPLETED
Conditions: Herpes Simplex
Interventions: BIOLOGICAL: GSK208141 vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Topiramate for the Treatment of Methamphetamine Dependence - 1
Status: COMPLETED
Conditions: Methamphetamine
Interventions: DRUG: Topiramate|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Web-Based Animated Training:Mother-Child School
Status: NOT_YET_RECRUITING
Conditions: Toilet Training|Autism|Breast Feeding
Interventions: COMBINATION_PRODUCT: experimental group|COMBINATION_PRODUCT: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparative Study on Two Post-operative Adjuvant Chemotherapy Regimens for Treating Triple-negative Breast Cancer
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: DRUG: 5-Fu/epirubicin/CTX following Docetaxel|DRUG: Docetaxel/capecitabine followed by XEC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Metformin and Polysorbate 80 on Drug Absorption and Disposition
Status: COMPLETED
Conditions: Bile Salt Export Pump (BSEP) Transporter|Polysorbate 80
Interventions: DRUG: pravastatin and chenodeoxycholic acid, after metformin and placebo|DRUG: valacyclovir, chenodeoxycholic acid, and enalaprilat, after polysorbate 80 and placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety of DNP007 in Healthy Subjects
Status: RECRUITING
Conditions: Liver Transplant Rejection|Liver Transplant; Complications|Steatohepatitis, Nonalcoholic
Interventions: DRUG: DNP007
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Direct Swallowing Training and Oral Sensorimotor Stimulation in Preterm Infants
Status: ACTIVE_NOT_RECRUITING
Conditions: Premature Birth of Newborn|Intervention Studies
Interventions: OTHER: Direct swallowing training (DST)|OTHER: Oral sensorimotor stimulation (OSMS)|OTHER: Sham intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Randomized, Double-blind Safety and Efficacy Study of Lisdexamfetamine Dimesylate (LDX) in Children and Adolescents Aged 6-17
Status: COMPLETED
Conditions: ADHD
Interventions: DRUG: Lisdexamfetamine Dimesylate (LDX)|DRUG: Methylphenidate Hydrochloride|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Particulate vs. Nonparticulate Epidural Steroid Injections for Lumbar Foraminal Stenosis
Status: WITHDRAWN
Conditions: Lumbar Spinal Stenosis
Interventions: DRUG: Kenalog Injectable Product|DRUG: Decadron Phosphate, Injectable|PROCEDURE: Epidural Steroid Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Effect of Instrument-assisted Soft Tissue Mobilization Versus Myofascial Release in Treatment of Mechanical Neck Pain
Status: COMPLETED
Conditions: Neck Pain|Soft Tissue Injuries
Interventions: OTHER: Instrument-assisted soft tissue mobilization|OTHER: Myofascial release therapy|OTHER: Postural correction exercises (PCE)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bronchoscopy and Bispectral Index (BIS) - Guided Sedation
Status: COMPLETED
Conditions: Bronchoscopy
Interventions: DRUG: Propofol|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A First in Human, Single Dose, Safety and Tolerability Study of MKC253 Inhalation Powder in Healthy Adult Males
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Healthy Males
Interventions: DRUG: MKC253 Inhalation Powder
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Enoxaparin Sodium on the Incidence of Deep Vein Thrombosis Following Electrophysiology Studies and Radiofrequency Ablation.
Status: TERMINATED
Conditions: Deep Vein Thrombosis
Interventions: DRUG: Clexane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy of a Scarf to Facilitate Mother-newborn Contact Designed to Facilitate Skin-to-skin Contact
Status: COMPLETED
Conditions: Full-term Newborn Babies
Interventions: DEVICE: Scarf|OTHER: Usual clinical practice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of Alignment Achieved Using the VELYS Robotic-Assisted Solution Versus Manual Instrumentation in Total Knee Arthroplasty
Status: COMPLETED
Conditions: Osteo Arthritis Knee|Osteoarthritis
Interventions: DEVICE: Total Knee Replacement
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Influence of Marker of Insulin Resistance Upon Hepatitis C Virus (HCV) Treatment Responses to PEG Intron and Rebetol Therapy
Status: COMPLETED
Conditions: Chronic Hepatitis C
Interventions: DRUG: PEG-Intron Plus REBETOL
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity & Reactogenicity of Boostrix 10 Years After Previous Booster Vaccination in Study NCT01267058
Status: COMPLETED
Conditions: Acellular Pertussis|Tetanus|Diphtheria|Diphtheria-Tetanus-acellular Pertussis Vaccines
Interventions: BIOLOGICAL: Boostrix™
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Lenstec Tetraflex Accommodating Posterior Chamber Intraocular Lens (IOL) Clinical Investigation
Status: COMPLETED
Conditions: Cataract
Interventions: DEVICE: posterior chamber IOL implantation|DEVICE: Experimental TetraFlex Study IOL
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Acupuncture on the Radial Pressure Pulse-wave at Cunkou in Low Back Pain
Status: COMPLETED
Conditions: Low Back Pain|Low Back Pain, Mechanical|Low Back Pain, Recurrent|Low Back Pain, Postural|Low Back Strain|Lumbago|Lumbago With Sciatica|Lumbago With Sciatica, Unspecified Side|Back Pain
Interventions: OTHER: Acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: n-3 and n-6 Fatty Acids in Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DIETARY_SUPPLEMENT: Fish oil, gamma-linolenic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of TT-00420 (Tinengotinib) in Subjects With Cholangiocarcinoma Who Failed or Relapsed to Chemotherapy and FGFR Inhibitor
Status: RECRUITING
Conditions: Cholangiocarcinoma Metastatic
Interventions: DRUG: TT-00420 (tinengotinib)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: LP0058-1005 - A Open-Label, Four-Way Crossover and Food-Effect Study of LEO 32731 in Healthy Subjects
Status: COMPLETED
Conditions: Psoriasis Vulgaris
Interventions: DRUG: LEO32731
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Multiple Ascending Doses (MAD) of AZD3199 Given Once Daily as Inhaled Formulation Via Turbuhaler to Healthy Men
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: AZD3199|DRUG: Placebo|DRUG: AZD3199|DRUG: AZD3199
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dimensional Brain Behavior Predictors of CBT Outcomes in Pediatric Anxiety
Status: COMPLETED
Conditions: Anxiety Disorders|Social Anxiety Disorder|Social Phobia|Generalized Anxiety Disorder|Separation Anxiety Disorder|Specific Phobia|Phobia|Agoraphobia|Panic Disorder|Panic Attack|Anxiety
Interventions: BEHAVIORAL: Cognitive Behavioral Therapy|BEHAVIORAL: Relaxation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study in Healthy Men to Measure the Amount of BI 730357 in the Blood When Taken as a Tablet
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BI 730357|DRUG: BI 730357 mixed with [C-14] BI 730357 BS
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trastuzumab, Cyclophosphamide, and Vaccine Therapy in Treating Patients With High-Risk or Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: BIOLOGICAL: allogeneic GM-CSF-secreting breast cancer vaccine|BIOLOGICAL: trastuzumab|DRUG: cyclophosphamide|OTHER: flow cytometry|OTHER: immunoenzyme technique|OTHER: immunohistochemistry staining method|OTHER: laboratory biomarker analysis|OTHER: pharmacological study|PROCEDURE: biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lorcaserin in Treating Chemotherapy-Induced Peripheral Neuropathy in Patients With Stage I-IV Gastrointestinal or Breast Cancer
Status: WITHDRAWN
Conditions: Anatomic Stage I Breast Cancer AJCC v8|Anatomic Stage IA Breast Cancer AJCC v8|Anatomic Stage IB Breast Cancer AJCC v8|Anatomic Stage II Breast Cancer AJCC v8|Anatomic Stage IIA Breast Cancer AJCC v8|Anatomic Stage IIB Breast Cancer AJCC v8|Anatomic Stage III Breast Cancer AJCC v8|Anatomic Stage IIIA Breast Cancer AJCC v8|Anatomic Stage IIIB Breast Cancer AJCC v8|Anatomic Stage IIIC Breast Cancer AJCC v8|Anatomic Stage IV Breast Cancer AJCC v8|Chemotherapy-Induced Peripheral Neuropathy|Digestive System Carcinoma|Prognostic Stage I Breast Cancer AJCC v8|Prognostic Stage IA Breast Cancer AJCC v8|Prognostic Stage IB Breast Cancer AJCC v8|Prognostic Stage II Breast Cancer AJCC v8|Prognostic Stage IIA Breast Cancer AJCC v8|Prognostic Stage IIB Breast Cancer AJCC v8|Prognostic Stage III Breast Cancer AJCC v8|Prognostic Stage IIIA Breast Cancer AJCC v8|Prognostic Stage IIIB Breast Cancer AJCC v8|Prognostic Stage IIIC Breast Cancer AJCC v8|Prognostic Stage IV Breast Cancer AJCC v8
Interventions: DRUG: Lorcaserin|DRUG: Lorcaserin Hydrochloride|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Eslicarbazepine Acetate on the Pharmacokinetics of Gliclazide in Healthy Volunteers
Status: COMPLETED
Conditions: Epilepsy
Interventions: DRUG: BIA 2-093|DRUG: Gliclazide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Balloon-occluded Retrograde Transvenous Obliteration for Gastric Variceal Rebleeding
Status: RECRUITING
Conditions: Gastric Varices Bleeding|Liver Decompensation
Interventions: DRUG: Sodium tetradecyl sulfate|DRUG: Cyanoacrylate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating The Safety And Tolerability Of Combination Therapy Inotuzumab Ozogamicin (CMC-544) And Rituximab
Status: COMPLETED
Conditions: Lymphoma, B-Cell
Interventions: DRUG: Inotuzumab Ozogamicin (CMC-544)|DRUG: Rituximab (Rituxan)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PDE4 Inhibition in Seborrheic Dermatitis and Papulopustular Rosacea
Status: RECRUITING
Conditions: Seborrheic Dermatitis|Papulopustular Rosacea
Interventions: DRUG: PF-07038124|DRUG: Placebo Ointment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Rubeosis Iridis With Open-Label Anecortave Acetate Sterile Suspension ( 15 mg.).
Status: TERMINATED
Conditions: Severe Diabetic Retinopathy|Central Retinal Vein Occlusion|Chronic Inflammation|Infectious Diseases
Interventions: DRUG: anecortave acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Multiradius and Singleradius Total Knee Arthroplasty
Status: UNKNOWN
Conditions: Gonarthrosis; Primary|Gonarthrosis|Gonarthrosis; Primary, Bilateral|Knee Osteoarthritis|Knee Arthritis
Interventions: PROCEDURE: singleradius and multiradius total knee arthroplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Uterine Massage Versus Sustained Uterine Compression on Blood Loss After Vaginal Delivery
Status: COMPLETED
Conditions: Postpartum Hemorrhage
Interventions: PROCEDURE: Uterine Massage|PROCEDURE: Uterine Compression
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Efficacy and Safety of Safinamide, as add-on Therapy, in Idiopathic Chinese Parkinson's Disease (PD) Patients With Motor Fluctuations Treated With Stable Doses of Levodopa
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: DRUG: Safinamide|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Biobehavioral/Cognitive Treatment for Stress, Depression, and Anxiety in Patients With Stage IV Lung Cancer
Status: COMPLETED
Conditions: Advanced Lung Carcinoma|Metastatic Lung Carcinoma|Stage IV Lung Cancer AJCC v8|Stage IVA Lung Cancer AJCC v8|Stage IVB Lung Cancer AJCC v8
Interventions: OTHER: Behavioral, Psychological or Informational Intervention|PROCEDURE: Biospecimen Collection|OTHER: Electronic Health Record Review|OTHER: Informational Intervention|OTHER: Survey Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pharmacokinetics of Vildagliptin in Mild, Moderate and Severe Renal Impaired Patients
Status: COMPLETED
Conditions: Renal Impairment|Diabetes
Interventions: DRUG: Vildagliptin|DRUG: Vildagliptin|DRUG: Vildagliptin|DRUG: Vildagliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Physiotherapeutic Intervention in Children With Chronic Functional Constipation
Status: COMPLETED
Conditions: Chronic Constipation
Interventions: OTHER: diaphragmatic breathing, isometric training of the abdominal muscles and abdominal massage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Withdrawal Effects Following Dosing of Oxycodone/Naltrexone in Methadone-Maintained Subjects
Status: COMPLETED
Conditions: Withdrawal Symptoms
Interventions: DRUG: Oxycodone/Naltrexone Capsules|DRUG: Oxycodone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Effect of Post-Operative Anesthetics on Post-Operative Pain in Patients Receiving Endodontic Treatment
Status: COMPLETED
Conditions: Endodontic Disease|Post Operative Pain|Symptomatic Irreversible Pulpitis
Interventions: DRUG: Local anesthetic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Tolerance, Efficacy, revAlidation, Myostim
Status: COMPLETED
Conditions: Anterior Cruciate Ligament Rupture
Interventions: DIETARY_SUPPLEMENT: MYOSTIM®|DIETARY_SUPPLEMENT: PLACEBO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Consolidation Therapy With Hu3S193 for Women With Ovarian, Primary Peritoneal or Fallopian Tube Cancer
Status: TERMINATED
Conditions: Fallopian Tube Cancer|Ovarian Cancer|Peritoneal Cavity Cancer
Interventions: BIOLOGICAL: Monoclonal antibody Hu3S193
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Determination of the Incidence of Endometriosis and or Adenomyosis in Patients Diagnosed With Polycystic Ovary Syndrome, or the Incidence of Polycystic Ovary Syndrome in Patients Diagnosed With Endometriosis and or Adenomyosis
Status: UNKNOWN
Conditions: Endometriosis|Polycystic Ovary Syndrome|Adenomyosis
Interventions: OTHER: incidence
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Boluses of Ringer's in Surgical Kids (BRiSK Study)
Status: ACTIVE_NOT_RECRUITING
Conditions: Dehydration in Children|Fluid Therapy
Interventions: DIAGNOSTIC_TEST: Urinalysis (UA)|DIAGNOSTIC_TEST: Complete Metabolic Panel (CMP)|DIAGNOSTIC_TEST: Glucose Stick Test (d-Stick)|OTHER: Medical Chart Review
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Assess the Efficacy and Safety of Ciclesonide Hydrofluoroalkane (HFA) Nasal Aerosol for the Treatment of Seasonal Allergic Rhinitis (SAR) to Mountain Cedar in Subjects 12 Years and Older
Status: COMPLETED
Conditions: Seasonal Allergic Rhinitis
Interventions: DRUG: Ciclesonide HFA 160 μg|DRUG: Ciclesonide HFA 80 μg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparison Between the Aysis® Cs2 (General Electrics) Ventilator in EtControl® Mode and the Perseus® A 500 (Dräger) in VaporView® Mode on Maniability and Consumption of Desflurane
Status: UNKNOWN
Conditions: Anesthetics Agent|Consumption|Inhalation|Desflurane
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Bemcentinib (BGB324) in Combination With Pembrolizumab in Patients With Advanced NSCLC
Status: COMPLETED
Conditions: Lung Cancer Metastatic|NSCLC Stage IV|Adenocarcinoma of Lung
Interventions: DRUG: Bemcentinib; pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigating the Pharmacokinetics, Safety and Tolerability After a Single Subcutaneous Injection of Semaglutide in Subjects With Mild, Moderate or Severe Hepatic Impairment Compared to Subjects With Normal Hepatic Function
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2|Hepatic Impaired
Interventions: DRUG: semaglutide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MIRACLE Study: A Study of Once-Monthly Intravenous Mircera in Hemodialysis Participants With Chronic Renal Anemia
Status: COMPLETED
Conditions: Anemia
Interventions: DRUG: Methoxy polyethylene glycol-epoetin beta
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of TTP399 in Patients With Type 1 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: DRUG: TTP399|DRUG: TTP399|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Retrospective Analysis of Pancreatic Injuries and Treatment Outcomes
Status: COMPLETED
Conditions: Pancreatic Trauma|Pancreatic Duct Injury|Pancreas Necrosis|Pancreas Cyst|Pancreas; Fistula|Pancreas Abscess|Intra-Abdominal Abscess|Anastomotic Leak|Pancreas Injury
Interventions: PROCEDURE: Exploratory laparotomy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study in Healthy Males to Assess Bioavailability of Single Fostamatinib With iv Micro Tracer Dose
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Fostamatinib|DRUG: Fostamatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety and Efficacy of Retifanlimab (INCMGA00012) Alone or in Combination With Other Therapies in Participants With Advanced or Metastatic Endometrial Cancer Who Have Progressed on or After Platinum-based Chemotherapy.
Status: RECRUITING
Conditions: Endometrial Cancer
Interventions: DRUG: retifanlimab|DRUG: epacadostat|DRUG: pemigatinib|DRUG: INCAGN02385|DRUG: INCAGN02390
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Best Practices to Prevent COVID-19 Illness in Staff and People With Serious Mental Illness and Developmental Disabilities in Congregate Living Settings
Status: UNKNOWN
Conditions: Intellectual Disability|Developmental Disability|Axis I Diagnosis|Mental Illness|Covid19|Coronavirus
Interventions: BEHAVIORAL: Generic Best Practices|BEHAVIORAL: Tailored Best Practices
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Follow up Study of Patients Undergoing Total Hip Arthroplasty CERAFIT® Grafted With Poly Sodium Styrene Sulfonate
Status: WITHDRAWN
Conditions: Hip Arthroplasty Replacement
Interventions: PROCEDURE: Total Hip Arthroplasty Replacement
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Minimum Effective Volume of Ropivacaine in Ultrasound-guided Supraclavicular Block
Status: COMPLETED
Conditions: Supraclavicular Brachial Plexus Block
Interventions: DRUG: Ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Exercise and Nutritional Supplementation
Status: COMPLETED
Conditions: Sarcopenia|Healthy Elderly|Healthy Young
Interventions: DIETARY_SUPPLEMENT: multi-nutrient supplement|OTHER: Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Multicentre Trial of Second-line Antiretroviral Treatment Strategies in African Adults Using Atazanavir or Lopinavir/Ritonavir
Status: WITHDRAWN
Conditions: HIV
Interventions: DRUG: Lopinavir|DRUG: Atazanavir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: STIMEP : Assessment of Subthalamic Nucleus Stimulation in Drug Resistant Epilepsy
Status: TERMINATED
Conditions: Epilepsy|Drug Resistant
Interventions: DEVICE: Neurostimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Radiofrequency Hyperthermia Safety Study
Status: COMPLETED
Conditions: Chronic Pain|Soft Tissue Injuries|Wound Heal|Blood Flow
Interventions: DEVICE: Laser Doppler|DEVICE: Radiofrequency Heating System|DEVICE: Thermal Imaging|OTHER: Healthcare Questionnaire & Measurement
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Eribulin in Combination With Cyclophosphamide in Patients With Solid Tumor Malignancies
Status: COMPLETED
Conditions: Malignant Solid Tumour|Breast Cancer Nos Metastatic Recurrent|Neuropathy
Interventions: DRUG: Eribulin|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exposure to CARDIovascular Risk Assessed by Cardiac Adiposity in oBese adOlescents Eligible to a Residential Long-term Lifestyle Intervention by Diet and eXercise (CARDIBOX)
Status: UNKNOWN
Conditions: Obesity|Adolescent Obesity
Interventions: BEHAVIORAL: 3-month lifestyle intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Femoral Nerve Block With Liposome Bupivacaine for Postsurgical Analgesia Following Total Knee Arthroplasty
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: Placebo|DRUG: EXPAREL 67 mg|DRUG: EXPAREL 133 mg|DRUG: EXPAREL 266 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I-II Study of Idarubicin, Cytarabine, and Sorafenib (BAY43-9006)
Status: COMPLETED
Conditions: AML|Acute Myeloid Leukemia|Myelodysplastic Disorders
Interventions: DRUG: Idarubicin|DRUG: Sorafenib|DRUG: Ara-C
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating the Efficacy and Tolerability of Veliparib in Combination With Paclitaxel/Carboplatin-Based Chemoradiotherapy Followed by Veliparib and Paclitaxel/Carboplatin Consolidation in Adults With Stage III Non-Small Cell Lung Cancer (NSCLC)
Status: TERMINATED
Conditions: Non-small Cell Lung Cancer Stage III
Interventions: DRUG: Paclitaxel|DRUG: Placebo for Veliparib|DRUG: Carboplatin|DRUG: Veliparib|RADIATION: Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Remimazolam Versus Propofol for General Anesthesia Induction in Patients on Renin-angiotensin System Blockers Undergoing Robot-assisted Laparoscopic Prostatectomy
Status: NOT_YET_RECRUITING
Conditions: Prostate Tumor
Interventions: DRUG: remimazolam|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Transcutaneous Auricular Vagus Nerve Stimulation on Dizziness & Balance in Elderly Population
Status: RECRUITING
Conditions: Vestibular Hypofunction
Interventions: OTHER: Vagus Nerve Stimulation (VNS) and Caw Thorne Cooksey|OTHER: Caw Thorne Cooksey
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Integrated Management Enhances Functional Gains in Children With Cerebral Palsy Treated by BoNT-A
Status: COMPLETED
Conditions: Cerebral Palsy
Interventions: DRUG: Botulinum toxin type A|DEVICE: transcranial direct current stimulation|OTHER: hybrid training model of CIMT and BIT|OTHER: usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Side Effects and How Well Anticancer Drugs Work in Very Young Patients With Cancer
Status: UNKNOWN
Conditions: Unspecified Childhood Solid Tumor, Protocol Specific
Interventions: DRUG: carboplatin|DRUG: cyclophosphamide|DRUG: etoposide phosphate|GENETIC: gene expression analysis|GENETIC: polymorphism analysis|OTHER: pharmacological study
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of Safety and Efficacy of 17-Beta Estradiol in Treatment of Atrophic Vaginitis: An Extension Trial
Status: COMPLETED
Conditions: Menopause|Postmenopausal Vaginal Atrophy
Interventions: DRUG: estradiol, 25 mcg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Efficacy and Long-Term Safety of Mometasone Furoate in Combination With Formoterol Fumarate Versus Mometasone Furoate in Children (5 to 11 Years of Age) With Persistent Asthma (MK-0887A-087)
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: MF MDI 100 mcg BID (Open Label)|DRUG: MF/F MDI 100/10 mcg BID|DRUG: MF MDI 100 mcg BID|DRUG: Albuterol/Salbutamol PRN|DRUG: Prednisone/Prednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Collection and Storage of Tissue Samples From Patients Undergoing Surgery For Suspected Solid Tumors
Status: RECRUITING
Conditions: Unspecified Adult Solid Tumor, Protocol Specific|Unspecified Childhood Solid Tumor, Protocol Specific
Interventions: OTHER: biologic sample preservation procedure|OTHER: medical chart review
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase II Safety and Immunogenicity Trial of Live Recombinant Canarypox ALVAC-HIV vCP205 With or Without HIV-1 SF-2 RGP120 in HIV-1 Uninfected Adult Volunteers
Status: COMPLETED
Conditions: HIV Infections
Interventions: BIOLOGICAL: MN rgp120/HIV-1 and GNE8 rgp120/HIV-1|BIOLOGICAL: MN rgp120/HIV-1 and A244 rgp120/HIV-1|BIOLOGICAL: ALVAC-HIV MN120TMG (vCP205)|BIOLOGICAL: rgp120/HIV-1 SF-2
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Trial of Tang-min-ling Pills in the Treatment of Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Tang-min-ling pills low dosage|DRUG: Tang-min-ling pills high dosage|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Study of Camtobell Inj (Belotecan) on Weekly Schedule in Non-small Cell Lung Cancer (NSCLC) Patients Previously Treated With Chemotherapy
Status: COMPLETED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: Belotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Controlled Study Comparing Three Different Techniques for Open Hernia Repair
Status: COMPLETED
Conditions: Inguinal Hernia
Interventions: PROCEDURE: Hernia repair|PROCEDURE: Hernia repair|PROCEDURE: Hernia repair
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of Raltegravir in Patients With Acute Tropical Spastic Paraparesis - Human T-Lymphotropic Virus 1 Infection
Status: COMPLETED
Conditions: HTLV-I Infections|Tropical Spastic Paraparesis
Interventions: DRUG: "Raltegravir" and "Zidovudine"
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Antihistamines on Pre-Pulse Inhibition
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Placebo|DRUG: Meclizine|DRUG: Meclizine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Surgical Scars Using the Pulsed Dye Laser
Status: COMPLETED
Conditions: Scar|Laser Therapy
Interventions: OTHER: Laser treatment with Purpuric settings|OTHER: Laser treatment with Nonpurpuric settings|OTHER: No treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pazopanib Hydrochloride, Paclitaxel, and Carboplatin in Treating Patients With Refractory or Resistant Ovarian Epithelial Cancer, Fallopian Tube Cancer, or Peritoneal Cancer
Status: COMPLETED
Conditions: Fallopian Tube Cancer|Ovarian Cancer|Primary Peritoneal Cavity Cancer
Interventions: DRUG: carboplatin|DRUG: paclitaxel|DRUG: pazopanib hydrochloride|OTHER: laboratory biomarker analysis|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Danazol With Plasma Exchange and Steroids for the Treatment of Thrombotic Thrombocytopenic Purpura (TTP)
Status: TERMINATED
Conditions: Thrombotic Thrombocytopenic Purpura
Interventions: DRUG: Danazol
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevalence of the Victimization and the Perpetration of Intimate Partner Violence Among the Patients From Puy-de-Dôme and Paris Consulting or Being Hospitalized for Addiction Problems and Their Expectations From General Practitioners (VIA-MG)
Status: COMPLETED
Conditions: Addiction|Violence, Domestic
Interventions: OTHER: questionnaire
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: COPE: Cannabinoids to Obviate Pain Experiment After Knee Replacement
Status: UNKNOWN
Conditions: Arthroplasty, Replacement, Knee
Interventions: DRUG: Cannabinol|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acupuncture and Escitalopram for Treating Major Depression Clinical Study
Status: NOT_YET_RECRUITING
Conditions: Depressive Disorder, Major
Interventions: OTHER: acupuncture|OTHER: escitalopram|OTHER: sham-acupuncure|OTHER: escitalopram placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of Lu-177 DOTATATE (Lutathera®) in Unlicensed Indications
Status: NOT_YET_RECRUITING
Conditions: Bronchial and Thymic Neuroendocrine Tumour|Paraganglioma/ Phaeochromocytoma|Medullary Thyroid Carcinoma|Those Requiring Repeat Peptide Receptor Radionuclide Therapy
Interventions: DRUG: Lu-177 DOTATATE (Lutathera®)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of GAÏA Program Cognitive Remediation of Facial Affects Processing in Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: BEHAVIORAL: GAÏA - facial affect recognition targeted|BEHAVIORAL: RECOS - attentional process targeted
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Sensory Training On Pain Modulation, Cognition and Time to Fatigue in Healthy Adults
Status: WITHDRAWN
Conditions: Healthy Participants
Interventions: DEVICE: Active eMNS|DEVICE: Sham eMNS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: A Phase 1/2 Study of Betalutin for Treatment of Relapsed Non-Hodgkin Lymphoma
Status: COMPLETED
Conditions: Non-Hodgkin Lymphoma|Follicular Lymphoma
Interventions: DRUG: 10 MBq/kg Betalutin|DRUG: 15 MBq/kg Betalutin|DRUG: 20 MBq/kg Betalutin|DRUG: 40 mg lilotomab|DRUG: 100 mg/m2 lilotomab|DRUG: 60 mg/m2 lilotomab|DRUG: Rituximab|DRUG: 12.5 mBq/kg Betalutin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Building a Renewed ImaGe After Head & Neck Cancer Treatment
Status: COMPLETED
Conditions: Head and Neck Squamous Cell Carcinoma|Body Image Disturbance
Interventions: BEHAVIORAL: cognitive behavioral therapy, face to face|BEHAVIORAL: cognitive behavioral therapy, telemedicine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of a Glaucoma Therapy to Treat Open-Angle Glaucoma or Ocular Hypertension
Status: COMPLETED
Conditions: Open-angle Glaucoma|Ocular Hypertension
Interventions: DRUG: Brinzolamide 10 mg/ml + Timolol 5 mg/ml eye drops, suspension|DRUG: Dorzolamide 20 mg/ml + Timolol 5 mg/ml eye drops, solution (COSOPT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect Tenofovir Disoproxil Fumarate (TDF) and Tenofovir Alafenamide (TAF) on Small Intestine Gut Wall
Status: ACTIVE_NOT_RECRUITING
Conditions: HIV Infections|Weight Gain
Interventions: PROCEDURE: gastroscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Early Detection of Lower Extremity Lymphedema After Lymphadenectomy in Gynecological Cancer
Status: COMPLETED
Conditions: Lymphedema of Limb|Sentinel Lymph Node
Interventions: OTHER: Early lymphedema detection|OTHER: Usual follow-up
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Diabetic Small Fiber Neuropathy: Clinical, Electrophysiological and Neurosonographic Study
Status: COMPLETED
Conditions: Small Fiber Neuropathy|Diabetic Neuropathies|Autonomic Neuropathy|Diabetic Peripheral Neuropathy|Painful Diabetic Neuropathy|Diabetic Polyneuropathy
Interventions: DIAGNOSTIC_TEST: Clinical Evaluation/Questionnaires|DIAGNOSTIC_TEST: Nerve Conduction Study|DIAGNOSTIC_TEST: Small fiber electrodiagnostic tests|DIAGNOSTIC_TEST: Nerve Ultrasound|DIAGNOSTIC_TEST: Skin Biopsy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Alveolar Recruitment Maneuver During Pneumoperitoneum
Status: COMPLETED
Conditions: Oxygen Deficiency
Interventions: PROCEDURE: alveolar recruitment maneuver|PROCEDURE: conventional ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Motor Sparing Supraclavicular Block
Status: RECRUITING
Conditions: Anesthesia|Regional Anesthesia Morbidity
Interventions: PROCEDURE: ultrasound guided supraclavicular brachial plexus block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Effectiveness of Natrelle(TM) Cohesive Round Silicone-Filled Breast Implants
Status: COMPLETED
Conditions: Breast Augmentation|Breast Reconstruction|Revision of Augmentation or Reconstruction
Interventions: DEVICE: Natrelle(TM) Silicone-Filled Breast Implants
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: A Study to Compare the Safety and Efficacy of Romosozumab (AMG 785) Versus Placebo in Men With Osteoporosis
Status: COMPLETED
Conditions: Osteoporosis in Men
Interventions: BIOLOGICAL: Romosozumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Probiotic Lozenge Reduce Streptococcus Mutans in Plaque in Orthodontic Bracket Patients
Status: COMPLETED
Conditions: Malocclusion
Interventions: DRUG: Probiotic (L. brevis CD2 lozenges)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Dose-escalating Study to Evaluate the Immunogenicity and Safety of Rotavin-M1 Vaccine in Healthy Infants
Status: COMPLETED
Conditions: Diarrhea|Fever|Nausea|Vomit|Irritability
Interventions: BIOLOGICAL: Rotarix
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Study Comparing Tigecycline Versus Ceftriaxone Sodium Plus Metronidazole in Complicated Intra-abdominal Infection (cIAI)
Status: COMPLETED
Conditions: Appendicitis|Cholecystitis|Diverticulitis|Intra-Abdominal Abscess|Intra-Abdominal Infection|Peritonitis
Interventions: DRUG: tigecycline|DRUG: ceftriaxone plus metronidazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Implementing the Spotlight AQ Platform in Adolescent/ Young Adult (16-25 Years Old) Type 1 Diabetics (T1D)
Status: RECRUITING
Conditions: Type 1 Diabetes Mellitus
Interventions: OTHER: Spotlight AQ Survey platform
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Exercise Effects on Word Learning
Status: COMPLETED
Conditions: Aging|Aphasia
Interventions: BEHAVIORAL: Retrieval Practice + Moderate Intensity Exercise|BEHAVIORAL: Retrieval Practice + Gentle Stretching|BEHAVIORAL: Study Only + Moderate Intensity Exercise|BEHAVIORAL: Study Only + Gentle Stretching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Phase II Study of NGR-hTNF in Combination With Doxorubicin in Platinum-resistant Ovarian Cancer
Status: COMPLETED
Conditions: Ovarian Cancer
Interventions: DRUG: NGR-hTNF|DRUG: Pegylated liposomal doxorubicin|DRUG: Doxorubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Anlotinib in Adjuvant Therapy for High-grade Soft Tissue Sarcoma
Status: UNKNOWN
Conditions: Soft Tissue Sarcoma Adult|High Grade Sarcoma
Interventions: DRUG: Anlotinib Hydrochloride|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Peritoneal Lavage With Clindamycin-gentamicin on Laparoscopic Sleeve Gastrectomy
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Clindamycin-gentamicin irrigation|DRUG: Normal saline irrigation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Remimazolam and Scoliosis Orthopedics
Status: UNKNOWN
Conditions: Benzodiazepines
Interventions: DRUG: Remimazolam|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: DBPC Trial to Evaluate the Safety, Tolerability and Efficacy of Oral Litoxetine in Subjects With Urinary Incontinence
Status: COMPLETED
Conditions: Urinary Incontinence
Interventions: DRUG: Litoxetine|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neo-adjuvant Chemotherapy in Locally Advanced Gastric Cancer
Status: COMPLETED
Conditions: Stage T3-4NxM0 Gastric Cancer
Interventions: DRUG: Docetaxel|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of a Combined Aerobic and Resistance Exercise (CARE) Training Programme on Cardiometabolic Outcomes in Individuals With Chronic Spinal Cord Injury: A Randomised Controlled Trial
Status: NOT_YET_RECRUITING
Conditions: Spinal Cord Injury
Interventions: OTHER: Dietary energy restriction group (D)|OTHER: Dietary energy restriction and exercise group (D+E)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exercise and Learning and Memory in Multiple Sclerosis
Status: TERMINATED
Conditions: Multiple Sclerosis|Physical Activity|Memory Impairment|Cognitive Change
Interventions: BEHAVIORAL: Treadmill Walking Exercise Training|BEHAVIORAL: Stretching-and-toning Exercise Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pembrolizumab and Enfortumab Vedotin With Pembrolizumab Prior to and After Radical Nephroureterectomy for High-Risk Upper Tract Urothelial Cancer
Status: NOT_YET_RECRUITING
Conditions: Renal Pelvis and Ureter Urothelial Carcinoma
Interventions: PROCEDURE: Biopsy|PROCEDURE: Biospecimen Collection|DRUG: Enfortumab Vedotin|PROCEDURE: MR Urography|PROCEDURE: Nephroureterectomy|BIOLOGICAL: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT