pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Reliability and Reproducibility of the Eye Check Tonometer
Status: TERMINATED
Conditions: Glaucoma|Glaucoma, Suspect
Interventions: DEVICE: EyeCheck|DEVICE: Traditional Tonometer (Goldmann and Tonopen)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Dara-RVd Induction for Newly Diagnosed Multiple Myeloma With Autologous Stem Cell Transplantation
Status: NOT_YET_RECRUITING
Conditions: Newly Diagnosed Multiple Myeloma|Multiple Myeloma|Autologous Stem Cell Transplantation
Interventions: BIOLOGICAL: Daratumumab|DRUG: Lenalidomide|DRUG: Bortezomib|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intra-articular Hyaluronic Acid Injection for Therapy-resistant Patellofemoral Pain Syndrome
Status: UNKNOWN
Conditions: Patellofemoral Pain Syndrome
Interventions: DEVICE: Hylan G-F 20
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Efficacy and Safety Study of Extended-Release (ER) Paliperidone in Adolescent Participants With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Paliperidone extended release (ER)|DRUG: Aripiprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Single Dose Escalation Trial to Evaluate the Safety, Tolerability Pharmacokinetics and Pharmacodynamics of GSK3050002
Status: COMPLETED
Conditions: Colitis, Ulcerative
Interventions: DRUG: GSK3050002|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Explore the Efficacy and Safety of Once-daily Oral Rivaroxaban for the Prevention of Cardiovascular Events in Subjects With Nonvalvular Atrial Fibrillation Scheduled for Cardioversion
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DRUG: Rivaroxaban (Xarelto, BAY59-7939)|DRUG: Vitamin K antagonist (VKA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Subthalamic Deep Brain Stimulation (DBS) in Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: PROCEDURE: Transcranial Magnetic Stimulation (TMS)|PROCEDURE: Motor Physiology Testing
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Evaluating Replacement of Standard-of-care Low Dose Computer Tomography (CT) Scans With Radiation-free Bone Imaging by Deep-learning Augmented Zero Echo Time (DL-ZTE) Magnetic Resonance Tomography (MRT)
Status: RECRUITING
Conditions: Joint Diseases|Joint Inflammation
Interventions: RADIATION: Low Dose Computer Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: An Open-Label Study of YM087 (Conivaptan) in Patients With Euvolemic or Hypervolemic Hyponatremia
Status: COMPLETED
Conditions: Hyponatremia
Interventions: DRUG: conivaptan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomised Controlled Trial of N-acetylcysteine for the Management of Alcohol Use Disorder
Status: RECRUITING
Conditions: Alcohol Use Disorder (AUD)
Interventions: DRUG: N-acetyl cysteine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination of Ibuprofen, G-CSF and Plerixafor as Stem Cells Mobilization Regimen in Patients Affected by X-CGD
Status: RECRUITING
Conditions: Chronic Granulomatous Disease X-linked (X-CGD)
Interventions: DRUG: Ibuprofen|DRUG: Myelostim|DRUG: Mozobil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: European Long-acting Antipsychotics in Schizophrenia Trial
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Aripiprazole|DRUG: Aripiprazole depot|DRUG: Paliperidone|DRUG: Paliperidone palmitate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Open-label Study to Evaluate Efficacy and Tolerability of TLC399 in Patients With Macular Edema Due to RVO
Status: COMPLETED
Conditions: Central Retinal Vein Occlusion With Macular Edema|Branch Retinal Vein Occlusion With Macular Edema
Interventions: DRUG: TLC399
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Guided Versus Non-guided Pelvic Floor Exercises for Urinary Incontinence in Relapsing-Remitting Multiple Sclerosis
Status: COMPLETED
Conditions: Relapsing-Remitting Multiple Sclerosis|Urinary Incontinence
Interventions: PROCEDURE: Pelvic floor exercises guided by a physiotherapist|PROCEDURE: Non guided pelvic floor exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Taxotere New Indication - Gastric Cancer Treatment Registration Trial
Status: COMPLETED
Conditions: Stomach Neoplasms
Interventions: DRUG: 5-fluorouracil|DRUG: Cisplatin|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Donepezil Therapy and Changes of Symptoms and Glucose Metabolism in Patients With Dementia With Lewy Bodies (DLB)
Status: COMPLETED
Conditions: Dementia With Lewy Bodies (DLB)
Interventions: DRUG: Donepezil|DRUG: Donepezil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy of Endoscopic Transantral Surgical Approach in the Repair of Orbital Blow-Out Fractures
Status: UNKNOWN
Conditions: Orbital Floor Fracture
Interventions: PROCEDURE: endoscopic trans-antral approach|PROCEDURE: trans-orbital surgical approach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial of Androgen Deprivation, Docetaxel, and Enzalutamide for Metastatic Prostate Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Cancer|Prostate Adenocarcinoma
Interventions: DRUG: ADT+Docetaxel+Enzalutamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Custom Molded Foot Orthoses Effect on Foot Kinematics and Lower Extremity Electromyography During Walking and Running.
Status: COMPLETED
Conditions: Lower Extremity Pain of a Mechanical Origin
Interventions: DEVICE: Maximal Arch Subtalar Stabilization|DEVICE: Full Contact Orthosis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Comparison of JointRep® and Microfracture in Repair of Cartilage Lesions on the Femoral Condyle or Trochlea,
Status: RECRUITING
Conditions: Chondral Defect|Articular Cartilage Defect|Articular Cartilage Disorder of Knee
Interventions: DEVICE: JointRep®|PROCEDURE: Microfracture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 2, Single-Arm, Open-Label Study Evaluating the Efficacy and Safety of Single Agent GS 1101 (CAL 101) as Therapy for Previously Treated Chronic Lymphocytic Leukemia
Status: WITHDRAWN
Conditions: Chronic Lymphocytic Leukemia
Interventions: DRUG: GS-1101
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of Protective Efficacy of Quadrivalent Recombinant Norovirus Vaccine (Pichia Pastoris)
Status: RECRUITING
Conditions: Acute Gastroenteropathy Due to Norovirus
Interventions: BIOLOGICAL: quadrivalent recombinant norovirus vaccine (Pichia pastoris)|BIOLOGICAL: quadrivalent recombinant norovirus vaccine (Pichia pastoris) placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Serotonin-receptor Agonism in Reward Processing
Status: COMPLETED
Conditions: Anhedonia
Interventions: DRUG: Buspirone 20mg|DRUG: Placebo comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Electrophysiological Effects of Late PCI After MI
Status: COMPLETED
Conditions: Cardiovascular Diseases|Heart Diseases|Myocardial Infarction|Coronary Disease|Arrhythmia|Ventricular Fibrillation
Interventions: PROCEDURE: PCI|DRUG: Optimal Medical Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Cesarean Scar After Three Different Uterine Closure Technis
Status: COMPLETED
Conditions: Cesarean Section, Repeated|Cesarean, Uterine Scar Thickness|Cesarean, Residual Myometrial Thickness
Interventions: PROCEDURE: Single layer closure|PROCEDURE: Double layer closure|PROCEDURE: Doble layer closure with trimming
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ALG-055009 in Non-cirrhotic Adults With MASH (HERALD)
Status: ACTIVE_NOT_RECRUITING
Conditions: NASH|MASH|Metabolic Dysfunction-Associated Steatohepatitis|Nonalcoholic Steatohepatitis
Interventions: DRUG: ALG-055009|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Low-dose Baricitinib Plus Danazol for Steroid-resistant/Relapse Immune Thrombocytopenia
Status: RECRUITING
Conditions: Immune Thrombocytopenia
Interventions: DRUG: Baricitinib 2 MG [Olumiant]|DRUG: Danazol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intracoronary Adenosine Administration to Prevent Periprocedural Myonecrosis in Elective Coronary Angioplasty
Status: COMPLETED
Conditions: Coronary Angioplasty
Interventions: DRUG: Adenosine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Prevention of Spinal Induced Shivering During CS
Status: COMPLETED
Conditions: Spinal Induced Shivering
Interventions: DRUG: Granisetron|DRUG: Granisetron|DRUG: Sodium chloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Rural Tailored COVID-19 Communication to Promote SARS-CoV-2 Antibody Testing in Saliva
Status: ACTIVE_NOT_RECRUITING
Conditions: SARS-CoV2 Infection
Interventions: BEHAVIORAL: General SARS-CoV-2 Communication|BEHAVIORAL: Rural-Targeted SARS-CoV-2 Communication
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SCREENING
Clinical trial: Curcumin in Treating Patients With Familial Adenomatous Polyposis
Status: COMPLETED
Conditions: Familial Adenomatous Polyposis
Interventions: DRUG: Curcumin|OTHER: Laboratory Biomarker Analysis|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Tolerability of Zolmitriptan Nasal Spray
Status: COMPLETED
Conditions: Migraine
Interventions: DRUG: Zolmitriptan|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Exenatide and Pramlintide to Decrease Post-prandial Hyperglycemia
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: DRUG: Pramlintide|DRUG: Exenatide|DRUG: Insulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ph II Nintedanib vs. Ifosfamide in Soft Tissue Sarcoma
Status: TERMINATED
Conditions: Sarcoma, Soft Tissue
Interventions: DRUG: Nintedanib|DRUG: Ifosfamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Relative Bioavailability Study of Candesartan Cilexetil Under Fasting Conditions
Status: COMPLETED
Conditions: Cardiovascular Disease
Interventions: DRUG: Candesartan Cilexetil in formulation 1|DRUG: Candesartan Cilexetil in formulation 2|DRUG: ATACAND
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Incidence of Neurogenic Paraosteoarthropathies in a Population of Brain Traumatized and Spinal Cord Injured Patients and Specific Markers of Early NPOA Development"
Status: NOT_YET_RECRUITING
Conditions: Spinal Cord Injuries|Injury, Brain, Traumatic
Interventions: OTHER: standard of care for patient with brain trauma and spinal cord injury
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Measuring Adherence to Control Hypertension
Status: COMPLETED
Conditions: Hypertension
Interventions: BEHAVIORAL: Disclosure of adherence report to clinician|DEVICE: MedSignals pillbox
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of 611 in Combination With Topical Corticosteroid in Participants With Moderate to Severe Atopic Dermatitis
Status: NOT_YET_RECRUITING
Conditions: Dermatitis, Atopic|Eczema, Atopic
Interventions: DRUG: 611|DRUG: Placebo|DRUG: Topical corticosteroid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of "Dose-dense Therapy" by S-HAM in Comparison to Conventionally Timed Double Induction in Patients With Acute Myeloid Leukemia (AML)
Status: COMPLETED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Ara-C, Mitoxantrone, Daunorubicin, Thioguanin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Sustamine(TM) on Cycling Time Trial Performance
Status: UNKNOWN
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Placebo Beverage|DIETARY_SUPPLEMENT: 2.8 g Sustamine Beverage|DIETARY_SUPPLEMENT: 19.6 g Sustamine Beverage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Durvalumab and Consolidation SBRT Following Chemoradiation for Locally Advanced Stage III Non-Small Cell Lung
Status: ACTIVE_NOT_RECRUITING
Conditions: Stage III Non-small-cell Lung Cancer
Interventions: DRUG: Durvalumab|RADIATION: SBRT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Trial to Assess Moxifloxacin in Treating Community-Acquired Pneumonia (CAP) With Aspiration Factors
Status: UNKNOWN
Conditions: Community-Acquired Pneumonia
Interventions: DRUG: moxifloxacin|DRUG: levofloxacin|DRUG: metronidazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of Bonded Versus Banded Space Maintainers
Status: UNKNOWN
Conditions: Tooth Loss
Interventions: DEVICE: 0.7 mm stainless steel orthodontic wire|DEVICE: Banded space maintainer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Telavancin for Treatment of Uncomplicated Staphylococcus Aureus Bacteremia
Status: COMPLETED
Conditions: Gram-Positive Bacterial Infections
Interventions: DRUG: Telavancin|DRUG: Vancomycin, nafcillin, oxacillin, or cloxacillin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Methylphenidate for Treating Attention Deficit Hyperactivity Disorder in Children With Both ADHD and Epilepsy
Status: COMPLETED
Conditions: Attention Deficit Disorder With Hyperactivity|Epilepsy
Interventions: DRUG: Extended Release Methylphenidate (OROS-Methylphenidate)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Continuation of TRAVERSE- LTS12551 Evaluating Dupilumab Safety in Patients With Asthma (Long-Term Follow-Up)
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Dupilumab SAR231893 (REGN668)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Microfluidic Chip Method Versus Density Gradient Centrifugation Method on Semen Parameters
Status: RECRUITING
Conditions: Infertility
Interventions: DEVICE: ZyMōt Multi 850µL device|DEVICE: Density Gradient Centrifugation Method
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Molecularly Target Therapy With GEMOX in Advanced or Recurrent Extrahepatic Cholangiocarcinoma and Gallbladder Carcinoma
Status: UNKNOWN
Conditions: Cholangiocarcinoma of the Extrahepatic Bile Duct|Gallbladder Cancer
Interventions: PROCEDURE: biological test|DRUG: GEMOX|DRUG: Cetuximab|DRUG: Trastuzumab|DRUG: Gefitinib|DRUG: Lapatinib|DRUG: Everolimus|DRUG: Sorafenib|DRUG: Crizotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Patient Outcomes in Simulation Education (POISE) Intravenous (IV) and Lumbar Puncture (LP) Multi-institution Protocol
Status: COMPLETED
Conditions: Infant Lumbar Puncture
Interventions: OTHER: Simulation-based mastery learning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Human Mesenchymal Stem Cells Induce Liver Transplant Tolerance
Status: UNKNOWN
Conditions: Evidence of Liver Transplantation
Interventions: DRUG: Conventional plus UC-MSC|DRUG: Conventional plus placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BALANCE+ Vanguard Phase
Status: RECRUITING
Conditions: Gram-negative Bacteremia
Interventions: OTHER: De-escalation VS No De-escalation|OTHER: Oral beta-lactams VS non beta-lactams|OTHER: Central vascular catheter retention VS Central vascular catheter replacement|OTHER: Cephalosporin VS Carbapenem for low risk AmpC organisms|OTHER: Routine follow-up blood culture VS No routine follow-up blood culture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study to Investigate the Pharmacokinetics, Safety, and Tolerability of Two Different Formulations of Long-acting Cabotegravir in Healthy Adult Participants
Status: RECRUITING
Conditions: HIV Infections
Interventions: DRUG: Cabotegravir Formulation F|DRUG: Cabotegravir Formulation G
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sodium Benzoate for Treatment of Attenuated/Transient Psychosis. A Randomized Placebo-controlled Trial.
Status: WITHDRAWN
Conditions: Attenuated or Transient Psychosis
Interventions: DRUG: Sodium Benzoate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Humanized Anti-IL-2 Receptor Monoclonal Antibody in Moderate-to-severe Ulcerative Colitis
Status: COMPLETED
Conditions: Ulcerative Colitis|Gastrointestinal Disease|Inflammatory Bowel Disease
Interventions: DRUG: Daclizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Bevacizumab Combined With Double Dose Icotinib in Patients With EGFR Exon 21-L858R Mutation
Status: RECRUITING
Conditions: Carcinoma, Non-Small-Cell Lung|Bevacizumab|EGF-R Positive Non-Small Cell Lung Cancer|Tyrosine Kinase Inhibitor
Interventions: DRUG: Bevacizumab and Icotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vemurafenib Plus Cobimetinib After Radiosurgery in Patients With BRAF-mutant Melanoma Brain Metastases
Status: TERMINATED
Conditions: Malignant Melanoma Stage IV|BRAF V600 Mutation|Brain Metastases
Interventions: DRUG: Vemurafenib|DRUG: Cobimetinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Study of Autologous Followed by Nonmyeloablative Allogeneic Transplantation Using TLI & ATG
Status: COMPLETED
Conditions: Transplantation, Homologous|Transplantation, Autologous|Multiple Myeloma|Blood and Marrow Transplant (BMT)
Interventions: PROCEDURE: Autologous peripheral blood stem cells (auto-PBSC) transplantation|PROCEDURE: Allogeneic peripheral blood stem cells (allo-PBSC) transplantation|DRUG: Filgrastim|DRUG: Cyclophosphamide|DRUG: Melphalan|DRUG: Cyclosporine|RADIATION: Total lymphoid irradiation|BIOLOGICAL: Rabbit anti-thymocyte globulin|DRUG: Mycophenolate Mofetil 250mg|DRUG: Solumedrol|DRUG: Diphenhydramine|DRUG: Acetaminophen|DRUG: Hydrocortisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Macronutrients on Satiety and Gut Hormone Responses
Status: COMPLETED
Conditions: Eating Behavior
Interventions: DIETARY_SUPPLEMENT: Protein stomach|DIETARY_SUPPLEMENT: Protein distal small intestine|DIETARY_SUPPLEMENT: CHO stomach|DIETARY_SUPPLEMENT: CHO distal small intestine|DIETARY_SUPPLEMENT: Fat stomach|DIETARY_SUPPLEMENT: Fat distal small intestine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of Acthar Gel Alone or With Tacrolimus to Reduce Proteinuria in Fibrillary Glomerulopathy Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Fibrillary Glomerulonephritis
Interventions: DRUG: Acthar Gel 80 UNT/ML Injectable Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Post Anesthesia Emergence and Behavioral Changes in Children Undergoing MRI
Status: TERMINATED
Conditions: Delirium on Emergence
Interventions: DRUG: Propofol|DRUG: Propofol|DRUG: Sevoflurane|DRUG: Isoflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Reducing the Burden of Malaria in HIV-uninfected Pregnant Women and Infants
Status: COMPLETED
Conditions: Malaria
Interventions: DRUG: Monthly dihydroartemisinin-piperaquine (DP) for adult women during pregnancy|DRUG: 3 dose dihydroartemisinin-piperaquine (DP) for adult women during pregnancy|DRUG: 3 dose sulfadoxine-pyrimethamine (SP) for adult women during pregnancy|DRUG: Monthly dihydroartemisinin-piperaquine (DP) for infants|DRUG: 3-monthly dihydroartemisinin-piperaquine (DP) for infants
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Omega-3 Fatty Acids as an Adjunctive Therapy for Stimulants in Children With ADHD
Status: TERMINATED
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: DIETARY_SUPPLEMENT: Stimulants plus Lovaza|DRUG: Stimulants plus placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Activated T Lymphocytes Expressing CARs, Relapsed CD19+ Malignancies Post-Allo HSCT(CARPASCIO)
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-Hodgkin's Lymphoma|B-Cell ALL|B-Cell CLL
Interventions: GENETIC: CD19.CAR-CD28Z T Cells - dose escalation 2|GENETIC: CD19.CAR-CD28Z T Cells - dose escalation 1
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adjuvant Radiotherapy for Esophageal Squamous Cell Carcinoma With Positive Circumstantial Resection Margin
Status: NOT_YET_RECRUITING
Conditions: Esophageal Squamous Cell Carcinoma|Positive Circumferential Resection Margin
Interventions: RADIATION: radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety of and Immune Response to Dolutegravir in HIV-1 Infected Infants, Children, and Adolescents
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: DTG film-coated tablets|DRUG: DTG granules for suspension|DRUG: DTG dispersible tablets|DRUG: DTG dispersible tablets|DRUG: DTG dispersible tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Recombinant Human C1 Inhibitor for the Treatment of Acute Attacks in Patients With Hereditary Angioedema
Status: COMPLETED
Conditions: Hereditary Angioedema|Angioneurotic Edema
Interventions: DRUG: Recombinant Human C1 Inhibitor|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Randomized Double Blind Controlled Trial of niPGT-A in Women With RPL
Status: NOT_YET_RECRUITING
Conditions: Infertility
Interventions: GENETIC: Non-invasive Preimplantation genetic testing for aneuploidy status
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SCREENING
Clinical trial: Non-inferiority, Open-label, Multicenter and Randomized Clinical Trial About the Treatment of Mild to Moderate Persistent Allergic Rhinitis
Status: COMPLETED
Conditions: Allergic Rhinitis
Interventions: DRUG: Noex|DRUG: Budecort Aqua
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of DPP-4 Inhibition on Triglycerides
Status: SUSPENDED
Conditions: Type 2 Diabetes|Hypertriglyceridemia
Interventions: DRUG: Saxagliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: 68Ga-DOTA-FAPI and 177Lu-DOTA-FAPI Theranostic Pair in Patients With Various Types of Cancer (Locally Advanced or Metastatic Cancer)
Status: UNKNOWN
Conditions: 177Lu-DOTA-FAPI|68Ga-DOTA-FAPI|Theranostic
Interventions: DRUG: 68Ga-DOTA-FAPI, 177Lu-DOTA-FAPI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of The Clinical Effects Between Different Physical Therapy Tools in Patellofemoral Pain Patients
Status: UNKNOWN
Conditions: Patellofemoral Pain Syndrome
Interventions: DEVICE: Quadriceps strength training|DEVICE: Taping|DEVICE: Home exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: A Study of Zanidatamab in Combination With Chemotherapy Plus or Minus Tislelizumab in Patients With HER2-positive Advanced or Metastatic Gastric and Esophageal Cancers
Status: RECRUITING
Conditions: Gastric Neoplasms|Gastroesophageal Adenocarcinoma|Esophageal Adenocarcinoma
Interventions: DRUG: Zanidatamab|DRUG: Tislelizumab|DRUG: Trastuzumab|DRUG: Capecitabine|DRUG: Oxaliplatin|DRUG: Cisplatin|DRUG: 5-Fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Split-face Tolerability Comparison Between MetroGel® 1% vs Finacea® 15% in Subjects With Healthy Skin
Status: COMPLETED
Conditions: Skin Manifestations
Interventions: DRUG: metronidazole 1% gel|DRUG: azelaic acid 15% gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Paracetamol for Cancer Pain
Status: UNKNOWN
Conditions: Advanced Cancer|Opioid Use, Unspecified
Interventions: DRUG: paracetamol|DRUG: placebo tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A First Time in Human Study of GSK586529 in Healthy Volunteers
Status: COMPLETED
Conditions: Depressive Disorder and Anxiety Disorders
Interventions: DRUG: GSK586529 capsules|DRUG: GSK586529 tablets|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: |Primary Purpose: PREVENTION
Clinical trial: Diagnostic Performance of a Commercial Assay for the Detection of Neuronal Antibodies
Status: COMPLETED
Conditions: Paraneoplastic Neurological Syndrome|Autoimmune Encephalitis
Interventions: DIAGNOSTIC_TEST: Indirect immunofluorescence assay on tissue slides and cell-based assays with CSF and/or sera
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety of Paricalcitol for Reduction of Proteinuria in Kidney Transplant Recipients
Status: COMPLETED
Conditions: Disorder of Transplanted Kidney|Proteinuria|Albuminuria
Interventions: DRUG: Paricalcitol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Isovue 370 vs. Standard Protocol in Coronary Computed Tomographic Angiography (CTA)
Status: COMPLETED
Conditions: Coronary Computed Tomographic Angiography
Interventions: DRUG: Isovue 370|DRUG: Visipaque 320
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Effects of 'Seroquel-XR' on the Improvement of Neurocognitive Function in People At-risk Mental States(ARMS)
Status: UNKNOWN
Conditions: Abnormal Mental State|Schizophrenia
Interventions: DRUG: Quetiapine(Seroquel-XR) 50~800mg a day
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Medium Chain Triglycerides as an Adjunct to the Modified Atkins Diet for Women With Catamenial Epilepsy
Status: COMPLETED
Conditions: Epilepsy|Seizure|Catamenial Epilepsy|Medically Resistant Epilepsy|Medically Resistant Seizures
Interventions: DIETARY_SUPPLEMENT: betaquik®
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevention of Vitamin D Deficiency Following Pediatric CHD Surgery: a Phase II Dose Evaluation Randomized Controlled Trial Comparing Usual Care With a High Dose Pre-operative Supplementation Regimen Based on the Institute of Medicine Daily Upper Tolerable Intake Level
Status: COMPLETED
Conditions: Vitamin D Deficiency|Thoracic Surgery|Pediatric Disorders|Heart Defects, Congenital
Interventions: DIETARY_SUPPLEMENT: Cholecalciferol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Immunogenicity of a Paediatric Dose of Virosomal Hepatitis A Vaccine
Status: COMPLETED
Conditions: Hepatitis A
Interventions: BIOLOGICAL: Epaxal 0.25 mL|BIOLOGICAL: Epaxal 0.5 mL|BIOLOGICAL: Havrix Junior 0.5 mL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Relation Between Mean Arterial Pressure and Renal Resistive Index in the Early Phase of Septic Shock
Status: RECRUITING
Conditions: Septic Shock
Interventions: DEVICE: increase of mean arterial pressure at 80-85 mmHg.|DEVICE: increase of mean arterial pressure at 65-70 mmHg.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: IABP In AMI Patients With SCAI-B Study
Status: NOT_YET_RECRUITING
Conditions: Myocardial Infarction, Acute|Cardiogenic Shock
Interventions: DEVICE: IABP (Intra-aortic balloon pump ) implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Infection Tracking in Travellers. The Project Aims to Identify Profiles of Travel-associated Illness and to Follow up on Long-term Sequelae of Arboviral Infections and Malaria
Status: NOT_YET_RECRUITING
Conditions: Travel-Related Illness|Malaria|Dengue|Chikungunya|Zika|SARS-CoV Infection|MERS|Influenza|Diarrhea
Interventions: OTHER: Observational study
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effectiveness and Safety of Percutaneous Adhesiolysis Using Rac'z Catheter Versus Navi Catheter in Management of Failed Back Surgery Syndrome
Status: COMPLETED
Conditions: Failed Back Surgery Syndrome
Interventions: PROCEDURE: Racz adhesolysis|DEVICE: NAVI adhesolysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study To Evaluate The Efficacy And Safety Of Obinutuzumab In Patients With ISN/RPS 2003 Class III Or IV Lupus Nephritis
Status: ACTIVE_NOT_RECRUITING
Conditions: Lupus Nephritis
Interventions: DRUG: Obinutuzumab|DRUG: MMF|DRUG: Prednisone|DRUG: Placebo|DRUG: Methylprednisolone|DRUG: Acetaminophen|DRUG: Diphenhydramine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate BMS-986036 in Obese Adults With Type-2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus Type 2
Interventions: BIOLOGICAL: BMS-986036|BIOLOGICAL: Placebo (Matching with BMS-986036)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I Study of Dasatinib (BMS-354825) and Imatinib in Subjects With Chronic Myeloid Leukemia in Chronic Phase
Status: WITHDRAWN
Conditions: Myeloid Leukemia, Chronic, Chronic-Phase
Interventions: DRUG: Dasatinib in combination with imatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the CONVIVO System
Status: RECRUITING
Conditions: Glioblastoma|Glial Tumor|Brain Metastases|Meningioma|Schwannoma|Pituitary Tumor
Interventions: DIAGNOSTIC_TEST: CONVIVO system|OTHER: Conventional histologic evaluation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Clinical Evaluation of Dental Fluororsis Treatment Modalities
Status: COMPLETED
Conditions: Dental Fluorosis
Interventions: OTHER: Opalescence™ boost™ PF 40%|OTHER: Opalustre™|OTHER: MI-Paste Plus®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Investigate Psorax35 Supplementation in Patients With Psoriasis
Status: COMPLETED
Conditions: Psoriasis Vulgaris
Interventions: DIETARY_SUPPLEMENT: Psorax35|DIETARY_SUPPLEMENT: MCT oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Acute Consequences of Glucocorticoid Secretion in Overweight and Obese Individuals During Maximum Calorie Intake
Status: NOT_YET_RECRUITING
Conditions: Glucocorticoids|Overweight and Obesity|Overeating
Interventions: DRUG: Metyrapone And Hydrocortisone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Use of Stratafix Symmetric™ to Prevent Incisional Hernia in Gastrointestinal and Abdominal Surgery
Status: RECRUITING
Conditions: C.Surgical Procedure; Disruption of Wound, Suture
Interventions: DEVICE: Stratafix suture|DEVICE: Standard of care suture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Dose Evaluation Study of the Effect of Plug Placement on the Efficacy and Safety of the Latanoprost Punctal Plug Delivery System (L-PPDS) in Subjects With Ocular Hypertension or Open-Angle Glaucoma
Status: COMPLETED
Conditions: Glaucoma|Ocular Hypertension (OH)
Interventions: DRUG: Latanoprost-PPDS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Body-oriented Psychotherapy for Individuals With a History of Child Maltreatment and Trauma-related Symptoms
Status: NOT_YET_RECRUITING
Conditions: Safety, Psychological|Acceptability of Health Care|Psychological Safety|Maltreatment, Child|Post Traumatic Stress Disorder|Complex Post-Traumatic Stress Disorder
Interventions: BEHAVIORAL: SE-group|BEHAVIORAL: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intravenous Infusion of Lidocaine in ERCP
Status: UNKNOWN
Conditions: Sedation
Interventions: DRUG: Lidocaine|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Inducing Immune Quiescence to Prevent HIV Infection in Women
Status: COMPLETED
Conditions: HIV
Interventions: DRUG: Acetylsalicylic Acid (ASA)|DRUG: Hydroxychloroquine (HCQ)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Intermittent Oro-esophageal Tube Feeding vs. Nasogastric Tube Feeding on Dysphagia Patients After Stroke
Status: WITHDRAWN
Conditions: Stroke
Interventions: DEVICE: Intermittent Oro-esophageal Tube Feeding|DEVICE: Nasogastric Tube Feeding|BEHAVIORAL: comprehensive rehabilitation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: EFFECTS OF L-ARGININE SUPPLEMENTATION ON THE RECOVERY OF CARDIORESPIRATORY PARAMETERS AFTER SUBMAXIMAL EXERCISE TEST
Status: RECRUITING
Conditions: Nutrition, Healthy
Interventions: DIETARY_SUPPLEMENT: L-arginine|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Injection Site Cooling on Pain Experienced After the Administration of CNTX-4975-05 Into the Knee
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: OTHER: Ice Pack and Cooling Device|DRUG: CNTX-4975-05 (trans-capsaicin)|DRUG: CNTX-4975-05 (trans-capsaicin)|DRUG: CNTX-4975-05 (trans-capsaicin)|DRUG: Capsaicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Xerostomia by Herbal Preparation
Status: UNKNOWN
Conditions: Xerostomia
Interventions: DIETARY_SUPPLEMENT: Herbal extract granule|DIETARY_SUPPLEMENT: Placebo herbal extract granule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Feeding the Rainbow to Investigate Endothelial Dysfunction
Status: COMPLETED
Conditions: Dietary Modification|Cardiovascular Disease
Interventions: DIETARY_SUPPLEMENT: Chlorophyll complex, Standard Process|DIETARY_SUPPLEMENT: Betatene, sold as "Full Spectrum Carotenoid Complex"|OTHER: Small carotenoid-rich meals|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study on the Effect of 40 Hz Non-Invasive Light Therapy System
Status: RECRUITING
Conditions: Alzheimer's Disease
Interventions: DEVICE: Light Therapy System (LTS): Active Setting|DEVICE: Light Therapy System (LTS): Sham Setting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Online COgnitive Behavioural Therapy for Sleep and Mental Health for Older Adults With Insomnia and Subjective Cognitive Complaints
Status: RECRUITING
Conditions: Insomnia
Interventions: BEHAVIORAL: cognitive behavioral therapy for sleep, anxiety, and depression|BEHAVIORAL: education about healthy nutrition habits and communication in older age
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Proprioception of the Knee Post MIS TKA and MIS-QS TKA
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: PROCEDURE: total knee arthroplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Patient Report Outcome and Oncological Safety -Oncoplastic and Conventional BCS Cohort
Status: NOT_YET_RECRUITING
Conditions: Patient Reported Outcome|Oncological Safety|Breast-conserving Surgery|Breast Cancer Female
Interventions: PROCEDURE: oncoplastic breast-conserving surgery|PROCEDURE: conventional breast-conserving surgery
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Evaluate the Safety and Immunogenicity of GlaxoSmithKline Biologicals' Influenza Vaccine GSK3206641A Administered in Adults 18 to 64 Years of Age and 65 Years of Age and Older
Status: COMPLETED
Conditions: Influenza, Human
Interventions: BIOLOGICAL: FLU-Q-PAN H7N9 Formulation 1|BIOLOGICAL: FLU-Q-PAN H7N9 Formulation 2|BIOLOGICAL: FLU-Q-PAN H7N9 Formulation 3|BIOLOGICAL: AS03B|BIOLOGICAL: AS03A|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: R-EPOCH in Combination With Ibrutinib for Patients With Classical RT of CLL
Status: NOT_YET_RECRUITING
Conditions: Richter Transformation
Interventions: DRUG: R-EPOCH in Combination With Ibrutinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Vitamin D and Omega-3 Supplementation for Preventing Diabetes
Status: ACTIVE_NOT_RECRUITING
Conditions: Type 2 Diabetes
Interventions: DIETARY_SUPPLEMENT: Vitamin D3|DRUG: Omega-3 fatty acid (fish oil)|DIETARY_SUPPLEMENT: Vitamin D3 placebo|DRUG: Fish oil placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Gastrointestinal and Health-related Quality of Life Outcomes in Patients With Autoimmune Diseases Treated With Mycophenolate
Status: COMPLETED
Conditions: Autoimmune Disease
Interventions: DRUG: Enteric-coated Mycophenolate Sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oxytocin HIV Meth Study
Status: COMPLETED
Conditions: Amphetamine Use Disorders
Interventions: DRUG: Oxytocin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Is Mg do Improve the Glycemic Control in Patients Drink a Desalinate Water
Status: COMPLETED
Conditions: Diabetes Mellitus|Patients|Glucose, High Blood
Interventions: OTHER: Water|DIETARY_SUPPLEMENT: Water with low Mg|DIETARY_SUPPLEMENT: Water with high Mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Intravenous and Oral Fosfomycin in Hospitalised Neonates With Clinical Sepsis
Status: COMPLETED
Conditions: Neonatal SEPSIS
Interventions: DRUG: Standard of Care + Fosfomycin|PROCEDURE: PK|PROCEDURE: Analysis of Bacterial Isolates
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Effects of Transcutaneous Electrical Nerve Stimulation Protocols in Women With Overactive Bladder
Status: NOT_YET_RECRUITING
Conditions: Overactive Bladder
Interventions: OTHER: TENS 1|OTHER: TENS 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT