pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Low-dose Ketamine for Acute Pain in the Emergency Department
Status: UNKNOWN
Conditions: Pain
Interventions: DRUG: Ketamine|DRUG: Placebos|DRUG: Morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Music Therapy and Social Work Telehealth for Older Adult Well-Being
Status: RECRUITING
Conditions: Aging Well|Dementia|Telemedicine
Interventions: BEHAVIORAL: Music Therapy Telehealth|BEHAVIORAL: Non-Collaborative Social Work Telehealth|BEHAVIORAL: Collaborative Social Work Telehealth
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study to Evaluate Efficacy and Safety of Giredestrant Compared With Fulvestrant (Plus a CDK4/6 Inhibitor), in Participants With ER-Positive, HER2-Negative Advanced Breast Cancer Resistant to Adjuvant Endocrine Therapy (pionERA Breast Cancer)
Status: RECRUITING
Conditions: Estrogen Receptor-Positive, HER2-Negative Advanced Breast Cancer
Interventions: DRUG: Giredestrant|DRUG: Fulvestrant|DRUG: Abemaciclib|DRUG: Palbociclib|DRUG: Ribociclib|DRUG: LHRH Agonist|DIAGNOSTIC_TEST: FoundationOne Liquid CDx Assay (F1LCDx)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prediction of the Effectiveness of Hypofractionated Radiation Therapy in Early Stage Lung Cancer by Bio-imaging and Biomarkers
Status: TERMINATED
Conditions: Inoperable Early Stage Non-small Cell Lung Cancer
Interventions: RADIATION: hypofractionated radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunology Dysregulation in Lymphadenitis Tuberculosis : An Observational Study Using Patient' Block Paraffins 2019 Until 2021
Status: COMPLETED
Conditions: Lymphadenitis, Tuberculous|Immune Defect
Interventions: OTHER: Immuno-histochemical staining
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Dose-finding Study for SPM 962 in Advanced Parkinson's Disease Patients
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DRUG: SPM 962|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lot Consistency Clinical Trial of of Recombinant HPV Bivalent Vaccine in 9 to14 Years Old Healthy Female
Status: COMPLETED
Conditions: Cervical Intraepithelial Neoplasia|Cervical Cancer|Vaginal Intraepithelial Neoplasia|Vulvar Intraepithelial Neoplasia|Persistent Infection
Interventions: BIOLOGICAL: Recombinant Human Papillomavirus Bivalent (Types 16, 18) Vaccine (Escherichia coli) / Cecolin®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Liraglutide Effect and Action in Diabetes: Evaluation of Cardiovascular Outcome Results
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: liraglutide|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Study of BMS-986016 With or Without Nivolumab in Patients With Advanced Solid Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Cancer
Interventions: DRUG: Relatlimab|DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Belumosudil and Rituximab for Primary Treatment of Chronic Graft-Versus-Host-Disease
Status: RECRUITING
Conditions: Chronic Graft Versus Host Disease
Interventions: DRUG: Belumosudil|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 3, 28-week, Randomized, Double-blind, Placebo-controlled Safety and Efficacy Study of Nabiximols as an add-on Therapy in Subjects With Spasticity Due to Multiple Sclerosis.
Status: WITHDRAWN
Conditions: Spasticity|Multiple Sclerosis
Interventions: DRUG: Sativex|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: SARC044: A Phase II Trial of Bezuclastinib in Combination With Sunitinib in Patients With GIST
Status: RECRUITING
Conditions: Gastrointestinal Stromal Tumors|GIST
Interventions: DRUG: Bezuclastinib in combination with sunitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sunitinib in Treating Patients With Myelodysplastic Syndromes or Chronic Myelomonocytic Leukemia
Status: COMPLETED
Conditions: Chronic Myelomonocytic Leukemia|de Novo Myelodysplastic Syndromes|Myelodysplastic Syndromes|Secondary Myelodysplastic Syndromes
Interventions: DRUG: sunitinib malate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Men, Mood, and Attention Study: Examination of Alcohol, State Anger, and Emotion Regulation Sexual Aggression
Status: TERMINATED
Conditions: Alcohol Intoxication|Anger
Interventions: OTHER: Alcohol Administration|OTHER: Mood Induction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Buprenorphine for the Treatment of Neonatal Abstinence Syndrome
Status: COMPLETED
Conditions: Neonatal Abstinence Syndrome
Interventions: DRUG: buprenorphine|DRUG: Oral morphine solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of PCC Versus FFP in Patients Undergoing Heart Surgery
Status: COMPLETED
Conditions: Bleeding|Surgery|Transfusion
Interventions: DRUG: Prothrombin Complex Concentrate (PCC)|BIOLOGICAL: Fresh Frozen Plasma
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: REMOGEN® Omega Versus Cationorm® in the Treatment of Patients Suffering From Dry Eye
Status: TERMINATED
Conditions: Dry Eye
Interventions: DEVICE: Remogen|DEVICE: Cationorm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: NOrepinephrine and VasoprEssin Versus Norepinephrine aLone in Critically Ill Patients With Septic Shock
Status: WITHDRAWN
Conditions: Shock, Septic
Interventions: DRUG: Vasopressin|DRUG: Norepinephrine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial on Treatment With Inhaled Furosemide of Preterm and Term Neonates With Transient Tachypnoea
Status: COMPLETED
Conditions: Transient Tachypnoea of the Newborn
Interventions: DRUG: Furosemide|DRUG: Saline 0,9%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Suvorexant and Sleep's Benefits to Therapeutic Exposure for Posttraumatic Stress Disorder
Status: COMPLETED
Conditions: Posttraumatic Stress Disorder
Interventions: DRUG: suvorexant|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: To Evaluate the Safety and Efficacy of Human Derived Anti-BCMA CAR-T Injection for Subjects With R/R MM
Status: RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: Human Derived anti-BCMA CAR-T Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Comparison of Alb-PRF vs PRF on Postoperative Morbidity Following FGG Harvesting
Status: NOT_YET_RECRUITING
Conditions: Palate; Wound
Interventions: OTHER: control group|OTHER: Platelet-rich fibrin (PRF)|OTHER: Albumin Platelet Rich- Fibrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Observation of V-P Shunt and Application of "Three-step Disinfection" to Reduce Post-operative Infection Rate
Status: UNKNOWN
Conditions: Hydrocephalus|Ventriculoperitoneal Shunt
Interventions: PROCEDURE: Three-step disinfection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: The Pro-Parenting Study: Helping Parents Reduce Behavior Problems in Preschool Children With Developmental Delay
Status: COMPLETED
Conditions: Development Delay|Behavior Problem
Interventions: BEHAVIORAL: BPT-M|BEHAVIORAL: BPT-E
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Performance of Genetic Amplification by Polymerase Chain Reaction (PCR) and the "Mannan Antigenemia and Antimannan Antibodies Couple as a Means of Diagnosis and a Marker of Follow-up in Invasive Candidiasis.
Status: COMPLETED
Conditions: Invasive Candidiasis; Treatment With Echinocandin
Interventions: BIOLOGICAL: Blood sample taken on the day the treatment is initiated|BIOLOGICAL: Blood sample taken on day 3 after initiation of treatment|BIOLOGICAL: Blood sample taken on day 5 after initiation of|BIOLOGICAL: Blood sample taken on day 7 after initiation of treatment|BIOLOGICAL: Blood sample taken on day 10 after initiation of treatment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Radicle Calm 1: A Study of Health and Wellness Products on Feelings of Anxiety, Stress and Other Health Outcomes
Status: COMPLETED
Conditions: Anxiety|Stress
Interventions: DIETARY_SUPPLEMENT: Radicle Calm Study Placebo Control 1|DIETARY_SUPPLEMENT: Radicle Calm Study Placebo Control 2|DIETARY_SUPPLEMENT: Radicle Calm Study Active Product 1.1|DIETARY_SUPPLEMENT: Radicle Calm Study Active Product 2.1|DIETARY_SUPPLEMENT: Radicle Calm Study Active Product 2.2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: RM-1995 Photoimmunotherapy, as Monotherapy or Combined With Pembrolizumab, in Patients With Advanced CuSCC and HNSCC
Status: WITHDRAWN
Conditions: Cutaneous Squamous Cell Carcinoma|Head and Neck Squamous Cell Carcinoma
Interventions: COMBINATION_PRODUCT: RM-1995|BIOLOGICAL: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety and Efficacy Study of Doripenem in Participants With Nosocomial Pneumonia, Complicated Intra-Abdominal Infections and Urinary Tract Infections
Status: COMPLETED
Conditions: Infection|Cross Infection|Bacterial Infections|Pneumonia, Ventilator-Associated|Intra-abdominal Infections|Urinary Tract Infections
Interventions: DRUG: Doripenem
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HZA113091 Efficacy and Safety of Fluticasone Furoate/Vilanterol (GW642444) in Adults and Adolescents
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Fluticasone furoate/Vilanterol Inhalation Powder|DRUG: Fluticasone propionate/salmeterol Inhalation Powder|DRUG: Placebo (1)|DRUG: Placebo (2)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Aortic Arch Related Cerebral Hazard Trial (ARCH)
Status: COMPLETED
Conditions: Brain Infarction|Transient Ischemic Attack|Embolism
Interventions: DRUG: Warfarin|DRUG: Clopidogrel-aspirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Awake vs. Asleep Craniotomy for Non-eloquent Gliomas
Status: COMPLETED
Conditions: Intracranial Glioma
Interventions: PROCEDURE: Awake Anesthesia Protocol|PROCEDURE: Non-awake Anesthesia Protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Extension Study of Treprostinil Palmitil Inhalation Powder (TPIP) for Pulmonary Arterial Hypertension (PAH)
Status: RECRUITING
Conditions: Pulmonary Arterial Hypertension
Interventions: DRUG: Treprostinil Palmitil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sequential Treatment of CD20-positive Posttransplant Lymphoproliferative Disorder (PTLD)
Status: TERMINATED
Conditions: Post-transplantation Lymphoproliferative Disorder
Interventions: DRUG: Rituximab|DRUG: CHOP
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial to Assess the Safety of SOR102 in Healthy Participants and Patients With Ulcerative Colitis
Status: RECRUITING
Conditions: Ulcerative Colitis
Interventions: DRUG: SOR102|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Long Term Follow up Treatment With Levetiracetam in Subjects of 4 Years and Older With Generalized Epilepsy
Status: COMPLETED
Conditions: Generalized Epilepsy
Interventions: DRUG: Levetiracetam 166 mg|DRUG: Levetiracetam 250 mg|DRUG: Levetiracetam 500 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BIBR 277 Capsule in Patients With Essential Hypertension
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: BIBR277 low dose|DRUG: BIBR277 medium dose|DRUG: BIBR277 high dose|DRUG: Enalapril low dose|DRUG: Enalapril medium dose|DRUG: Enalapril high dose|DRUG: Placebo matching BIBR277|DRUG: Placebo matching enalapril
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Safety and Effectiveness of Tramadex-OD After Knee Arthroscopy
Status: UNKNOWN
Conditions: Postoperative Pain
Interventions: DRUG: extended-release tramadol|DRUG: paracetamol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Safety and Efficacy of a Tacrolimus New Oral Formulation (MR4) in BMT Patients-Extension-
Status: COMPLETED
Conditions: Bone Marrow Transplantation|Graft Versus Host Disease|Graft-Versus-Host Disease|Graft-Vs-Host Disease
Interventions: DRUG: Tacrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose Escalating Study of BPI-3016 in Healthy Subjects
Status: UNKNOWN
Conditions: Healthy Subject
Interventions: DRUG: BPI-3016|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effects of GLPG2737 in Participants With Autosomal Dominant Polycystic Kidney Disease (ADPKD)
Status: TERMINATED
Conditions: Autosomal Dominant Polycystic Kidney Disease
Interventions: DRUG: GLPG2737|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: TLK286 in Combination With Paraplatin (Carboplatin) in Recurrent Ovarian Cancer
Status: COMPLETED
Conditions: Ovarian Neoplasms
Interventions: DRUG: TLK286
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Brilinta Taiwan Post Approval Safety Study
Status: COMPLETED
Conditions: Non ST-elevation Myocardial Infarction
Interventions: DRUG: Ticagrelor 180mg loading dose taken orally, followed by 90mg twice daily (bd)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Morning Versus Bedtime Dosing of Antihypertensive Medication
Status: UNKNOWN
Conditions: Hypertension|Blood Pressure|Drug Use
Interventions: DRUG: Alisartan, Amlodipine besylate|DRUG: Alisartan, Amlodipine besylate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Allogeneic Stem Cell Transplant With Clofarabine, Busulfan and Antithymocyte Globulin (ATG) for Adult Patients With High-risk Acute Myeloid Leukemia/Myelodysplastic Syndromes (AML/MDS) or Acute Lymphoblastic Leukemia (ALL)
Status: COMPLETED
Conditions: MDS|AML|ALL|BAL
Interventions: DRUG: Clofarabine in combination with IV busulfan and ATG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multiprofessional Advance Care Planning and Shared Decision Making for End of Life Care
Status: COMPLETED
Conditions: Palliative Patients|Surrogate Decision Maker
Interventions: OTHER: Advance Care Planning ACP|OTHER: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Disease Characteristics of IR-CAD: a Case-control Study
Status: NOT_YET_RECRUITING
Conditions: Coronary Artery Disease|Coronary Artery Stenosis|Coronary Artery Restenosis|Coronary Artery Disease Progression|Inflammation|Inflammatory Disease|Inflammation Vascular
Interventions: DIAGNOSTIC_TEST: Protocol-defined Examinations
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Chronic Postoperative Pain After the Lichtenstein Groin Hernioplasty
Status: COMPLETED
Conditions: Hernia, Inguinal|Hernia, Femoral|Postoperative Pain|Chronic Pain|PROM|Suture Related Complication
Interventions: DEVICE: Lichtenstein mesh repair
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluating the Safety and Efficacy of Laight®-Therapy Treatment in Subjects With Hidradenitis Suppurativa
Status: COMPLETED
Conditions: Hidradenitis Suppurativa
Interventions: DEVICE: Laight therapy, NICE V3.1 device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: PK Study in Adult Healthy Volunteers to Assess QD Dosing With the Selected Age-appropriate MR Formulations
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: 10 mg dose MR formulations,10 mg dose of tofacitinib IR solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Audiological Benefit and Quality of Life With Two Bone Conduction Systems: ADHEAR vs. Contact Mini
Status: COMPLETED
Conditions: Conductive Hearing Loss
Interventions: DEVICE: Adhear|DEVICE: Contact Mini (CM)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Anastrozole Verses Clomiphene Citrate in Stimulating Follicular Growth and Ovulation in Infertile Women With Ovulatory Dysfunction
Status: COMPLETED
Conditions: Anovulation
Interventions: DRUG: Anastrozole 1 mg|DRUG: Anastrozole 5 mg|DRUG: Anastrozole 10 mg|DRUG: Clomiphene Citrate 50 mg|DRUG: Clomiphene Citrate 100 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: STEP UP to Avert Amputation in Diabetes
Status: COMPLETED
Conditions: Diabetes|Foot Ulcer
Interventions: BEHAVIORAL: Tailored Intervention (TI)|BEHAVIORAL: Current Practice (CP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study Evaluating the Safety, Tolerability and Immunogenicity of 13vPnC as a 2-Dose Regimen or With 23vPS
Status: COMPLETED
Conditions: Pneumococcal Vaccines
Interventions: BIOLOGICAL: 13 valent Pneumococcal Conjugate Vaccine|BIOLOGICAL: 13 valent Pneumococcal Conjugate Vaccine|BIOLOGICAL: 13 valent Pneumococcal Conjugate Vaccine|BIOLOGICAL: 23-valent Pneumococcal Polysaccharide Vaccine|BIOLOGICAL: 23-valent Pneumococcal Polysaccharide Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluating the Efficacy of Atezolizumab in Advanced Non-small Cell Lung Cancer (NSCLC)
Status: COMPLETED
Conditions: Advanced Non-small Cell Lung Cancer
Interventions: DRUG: Atezolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nursing Students& Breastfeeding Education& Simulation
Status: COMPLETED
Conditions: Breastfeeding
Interventions: OTHER: high-fidelity simulation|OTHER: hybrid simulation|OTHER: telesimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Clinical Trial Assessing Non-Inferiority of Freeze Dried Plasma to Fresh Frozen Plasma in Reversing Warfarin
Status: UNKNOWN
Conditions: Anticoagulant Reversal
Interventions: BIOLOGICAL: Fresh Frozen Plasma (FFP)|BIOLOGICAL: Freeze Dried Plasma (FDP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Myofascial Release Technique in Women With Primary Dysmenorrhea
Status: NOT_YET_RECRUITING
Conditions: Dysmenorrhea Primary|Central Sensitisation|Myofascial Trigger Point Pain|Menstrual Discomfort|Myofascial Release
Interventions: OTHER: Myofascial Release|OTHER: Sham-Myofascial Release
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of a POPOP on Preoperative Health, Eligibility, and Clinical & Patient-Reported Outcomes in TJA
Status: ACTIVE_NOT_RECRUITING
Conditions: Osteoarthritis, Knee|Osteoarthritis, Hip|Avascular Necrosis|Rheumatoid Arthritis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Two Mini-screws Supported Hyrax for Maxillary Expansion in Early Adulthood
Status: ACTIVE_NOT_RECRUITING
Conditions: Transverse Maxillary Deficiency
Interventions: DEVICE: Hybrid Hyrax
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Davos Alzheimer's Collaborative Study: Sequential Administration of Digital Testing To Screen For Cognitive Impairment Followed By Blood Based Biomarkers To Assist With Timely Detection And Accurate Diagnosis Of Alzheimer's Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Alzheimer Disease
Interventions: OTHER: Cognitive Assessment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Compare the Effects of Two Anti-HIV Drug Combinations on the Immune Systems of HIV-Infected Patients
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Ritonavir|DRUG: Efavirenz|DRUG: Saquinavir
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: Efficacy of 400 Mg Versus 800 Mg Imatinib in Chronic Myeloid Leukemia in Chronic Phase Patients - TOPS (Tyrosine Kinase Inhibitor Optimization and Selectivity)
Status: TERMINATED
Conditions: Leukemia, Myeloid, Chronic Phase
Interventions: DRUG: Imatinib mesylate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RCT of the Cutting Balloon Versus a High Pressure Balloon for the Treatment of Arteriovenous Fistula Stenoses
Status: WITHDRAWN
Conditions: Stenosis
Interventions: PROCEDURE: CUTTING BALLOON ANGIOPLASTY|PROCEDURE: Balloon angioplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comfort Talk for Pediatric Cardiac Catheterization
Status: COMPLETED
Conditions: Anxiety|Pain|Adaptation, Psychological|Stress, Psychological
Interventions: BEHAVIORAL: Reading pre-procedure script|BEHAVIORAL: Reading pre-extubation script|BEHAVIORAL: Reading 2 scripts
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study to Evaluate the REMEDY SPECTRUM IM Spacer Nail in the Treatment of Ankle-Related Infections
Status: NOT_YET_RECRUITING
Conditions: Periprosthetic Joint Infection
Interventions: COMBINATION_PRODUCT: REMEDY Spectrum IM Spacer Nail
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Stem Cells and Stem Cell Exosomes on Visual Functions in Patients With Retinitis Pigmentosa
Status: UNKNOWN
Conditions: Retinitis Pigmentosa
Interventions: BIOLOGICAL: Subtenon injection of Wharton jelly derived mesenchymal stem cells|BIOLOGICAL: Subtenon injection of Wharton jelly derived mesenchymal stem cell exosomes|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Study of Orelabrutinib in Patients With Relapsing-Remitting Multiple Sclerosis
Status: ACTIVE_NOT_RECRUITING
Conditions: Relapsing Remitting Multiple Sclerosis
Interventions: OTHER: placebo|DRUG: orelabrutinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transcranial Direct Current Stimulation (tDCS) in the Treatment of Major Depressive Disorder (MDD)
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DEVICE: transcranial direct current stimulation (tDCS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Escitalopram in Treating Depression in Patients With Advanced Lung or Gastrointestinal Cancer
Status: TERMINATED
Conditions: Colorectal Cancer|Depression|Esophageal Cancer|Extrahepatic Bile Duct Cancer|Fatigue|Gallbladder Cancer|Gastric Cancer|Liver Cancer|Lung Cancer|Pancreatic Cancer
Interventions: DRUG: escitalopram oxalate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of 2 Grams Daily Supplementation of Sativa Nigra Oil on Blood Glucose Levels of Adults.
Status: UNKNOWN
Conditions: Diabetes Mellitus
Interventions: DIETARY_SUPPLEMENT: Sativa Nigra oil Softgels|DIETARY_SUPPLEMENT: Activated Charcoal Softgels
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Indicating Direction and Angle for Cannulating of AV-fistula in Hemodialysis Patients
Status: COMPLETED
Conditions: Chronic Kidney Disease|Kidney Failure
Interventions: PROCEDURE: Skin drawing|PROCEDURE: No skin drawing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of 2 Techniques of Surgically Assisted Rapid Maxillary Expansion
Status: COMPLETED
Conditions: Malocclusion|Maxillar Hypoplasia|Transverse Maxillary Deficiency
Interventions: PROCEDURE: Osteotomy between the maxillary central incisors|PROCEDURE: Osteotomy between the maxillary lateral incisors and canines
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hyperbaric Bupivacaine Versus Hyperbaric Prilocaine 2% for Cesarean Section Under Spinal Anesthesia
Status: COMPLETED
Conditions: Pregnant Women|Pain|Hypotension
Interventions: DRUG: Hyperbaric bupivacaine|DRUG: Hyperbaric prilocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Estimate the Effect of CYP3A4 Inhibitors (Itraconazole, Diltiazem or Verapamil) on the Pharmacokinetics of Single Dose PF- 00489791 in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: itraconazole|DRUG: diltiazem|DRUG: SR verapamil|DRUG: PF-00489791
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pharmacokinetics, Pharmacodynamics, and Safety Study of Ticagrelor in Hemodialysis Patients and Healthy Subjects
Status: COMPLETED
Conditions: Kidney Failure, Chronic
Interventions: DRUG: ticagrelor|DRUG: ticagrelor|DRUG: ticagrelor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Insulin Detemir and NPH With Respect to Lowering the Blood Sugar and Symptoms Experienced by Type 1 Diabetics During Hypoglycaemia
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 1
Interventions: DRUG: insulin detemir|DRUG: insulin NPH
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Robotic-assisted Contra Open Resection for Suspected or Confirmed Gallbladder Cancer (ROBOCOP)
Status: RECRUITING
Conditions: Gall Bladder Cancer
Interventions: PROCEDURE: Robotic-assisted radical cholecystectomy|PROCEDURE: Open radical cholecystectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of Durvalumab or Tremelimumab Monotherapy, or Durvalumab in Combination With Tremelimumab or Bevacizumab in Advanced Hepatocellular Carcinoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: BIOLOGICAL: Tremelimumab|BIOLOGICAL: Durvalumab|BIOLOGICAL: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Trial of Erlotinib and Concurrent Palliative Thoracic Radiation Therapy for Non-small Cell Lung Cancer (PEARL)
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: Erlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Lower Limb Exercises on Overactive Bladder Symptoms in Patients With Multiple Sclerosis
Status: UNKNOWN
Conditions: Overactive Bladder Syndrome|Multiple Sclerosis|Muscle Strain
Interventions: OTHER: Usual physical therapy+ strengthening of lower limbs muscles|OTHER: Usual physical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Of Gastrointestinal Tolerability Of PF05212389 In Obese Subjects
Status: WITHDRAWN
Conditions: Obesity
Interventions: DRUG: PF 05212389 or placebo|DRUG: PF 05212389 or placebo|DRUG: PF 05212389 or placebo|DRUG: PF 05212389 or placebo|DRUG: PF 05212389 or placebo|DRUG: PF 05212389 or placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Does Rehabilitation After Total Hip and Knee Arthroplasty Work
Status: COMPLETED
Conditions: Arthroplasty, Replacement, Knee|Arthroplasty, Replacement, Hip|Telerehabilitation|Rehabilitation
Interventions: OTHER: Telerehabilitation|OTHER: No intervention|OTHER: Unsupervised rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Monthly Intravenous C.E.R.A. (Mircera) in Hemodialysis Participants With Chronic Renal Anemia
Status: COMPLETED
Conditions: Anemia
Interventions: DRUG: Methoxy polyethylene glycol-epoetin beta (C.E.R.A.)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Quality of Life Outcomes Following Minimally Invasive and Open Esophagectomy for Esophageal Cancer
Status: COMPLETED
Conditions: Esophageal Cancer
Interventions: BEHAVIORAL: Quality of Life instruments, FACT-E, Symptom Assessment Scale, Brief Pain Inventory and Daily Analgesic Log|BEHAVIORAL: Quality of Life instruments, FACT-E, Symptom Assessment Scale, Brief Pain Inventory and Daily Analgesic Log
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Chemotherapy Followed by ESO-1 Lymphocytes and Aldesleukin to Treat Metastatic Cancer
Status: TERMINATED
Conditions: Metastatic Melanoma|Metastatic Renal Cell Cancer|Metastatic Cancer
Interventions: BIOLOGICAL: Anti-NY ESO-1 T-cell receptor PBL|DRUG: aldesleukin|DRUG: Cyclophosphamide|DRUG: fludarabine phosphate|BIOLOGICAL: ALVAC NY ESO-1 vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of HCV-Infected Recent Injection Drug Users in U.S. Liver Clinics
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Hepatitis C|People Who Inject Drugs
Interventions: DRUG: velpatasvir and sofosbuvir once daily for 12 weeks (brand or branded generic) .
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Eating Pulses for 8 Weeks on Satiety and Metabolic Syndrome Risk Factors in Overweight Individuals
Status: COMPLETED
Conditions: Obesity|Overweight
Interventions: OTHER: Dietary advise|OTHER: Diet enriched with a meal containing pulses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: CHIEF-PD (CHolinesterase Inhibitor to prEvent Falls in Parkinson's Disease)
Status: ACTIVE_NOT_RECRUITING
Conditions: Parkinson Disease
Interventions: DRUG: Rivastigmine Transdermal System|OTHER: Placebo Transdermal System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Care Based on the Lactation Management Model Provided to Mothers With Babies in the Intensive Care Unit
Status: RECRUITING
Conditions: Amount of Breast Milk
Interventions: OTHER: Lactation Management Model
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: to Evaluate the Pharmacokinetics(Cmax, Auc) of CJ Imatinib Mesylate Tablet 200mg x 1 Compared With Gleevec Film-coated Tablet 100mg x 2 in Healthy Male Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: CJ Imatinib mesylate tablet|DRUG: Gleevec film-coated tablet 2 x 100mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety Study of 5-Azacitidine and Standard Donor Lymphocyte Infusion (DLI) to Treat Acute Myeloid Leukemia (AML) or Myelodysplastic Syndrome (MDS) Relapsing After Allogeneic Stem Cell Transplantation
Status: COMPLETED
Conditions: Myelodysplastic Syndrome|Acute Myeloid Leukemia
Interventions: DRUG: 5-Azacitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ABT-888, Carboplatin, and Paclitaxel for Cancer With Liver or Kidney Problems
Status: WITHDRAWN
Conditions: Neoplasms
Interventions: DRUG: ABT-888|DRUG: Carboplatin|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phased-Implementation Feasibility and Proof-of-Concept Study to Assess Incorporating the NIDA CTN Common Data Elements (CDEs) Into the Electronic Health Record (EHR) in Large Primary Care Settings ("CDE-EHR-PC" Study), Phase 3
Status: COMPLETED
Conditions: Substance Abuse
Interventions: BEHAVIORAL: Meetings with implementation leader(s)|BEHAVIORAL: the SAAS survey|BEHAVIORAL: Patient surveys
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Oxandrolone Compared With Megestrol in Preventing Weight Loss in Patients Receiving Chemotherapy for Cancer
Status: COMPLETED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific|Weight Changes
Interventions: DRUG: Megestrol Acetate|DRUG: Oxandrolone 20 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study Evaluating Pain Relief and Safety of Orally Administered CR845 in Patients With Osteoarthritis of Hip or Knee
Status: COMPLETED
Conditions: Osteoarthritis, Hip|Osteoarthritis, Knee|Arthritis|Joint Diseases|Musculoskeletal Diseases|Rheumatic Diseases
Interventions: DRUG: CR845 tablet 1 mg|DRUG: CR845 tablet 2.5 mg|DRUG: CR845 tablet 5 mg|DRUG: Placebo tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Antithrombin-III for Patients With Hepatic Veno-occlusive Diseases Following Hematopoietic Stem Cell Transplantation
Status: UNKNOWN
Conditions: Hepatic Veno-Occlusive Disease
Interventions: DRUG: Freeze-dried Concentrated Human Antithrombin Ⅲ 500 IU
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hardware Preservation in Management of Infected Non United or Delayed United Fractures of Long or Short Bones by Debridement and Local Calcium Sulfate Loaded by Antibiotics
Status: RECRUITING
Conditions: Infected Non Union and Delayed Union in Fractures of Both Long and Short Bones
Interventions: PROCEDURE: local debridement and local calcium sulfate loaded by antibiotics
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fatty Acid Biomarkers of Carbohydrate Intake
Status: COMPLETED
Conditions: Dyslipidemias
Interventions: OTHER: Low carbohydrate diet|OTHER: High carbohydrate, high sugar diet|OTHER: High carbohydrate, low sugar diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of SugarCut® Unripe Guava Fruit Extract on Blood Glucose Regulation
Status: RECRUITING
Conditions: PreDiabetes
Interventions: DIETARY_SUPPLEMENT: SugarCut® Unripe Guava Fruit Extract|DIETARY_SUPPLEMENT: Placebo group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Dose Escalation and Efficacy Trial of GVAX® Prostate Cancer Vaccine
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: BIOLOGICAL: Immunotherapy allogeneic GM-CSF secreting cellular vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Docetaxel+Oxaliplatin+S-1 (DOS) Regimen as Neoadjuvant Chemotherapy in Advanced Gastric Cancer
Status: COMPLETED
Conditions: Gastric Cancer
Interventions: DRUG: Docetaxel (XRP6976)|DRUG: Oxaliplatin (SR96669)|DRUG: S-1 (1-(2-tetrahydrofuryl)-5-fluorouracil + 5-chloro-2, 4-dihydroxypyridine (CDHP) (Gimeracil) + Oxo (Oteracil)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stereotactic Body Radiation Therapy Followed by Surgery in Treating Patients With Stage I-IIIA Non-small Cell Lung Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Stage I Non-Small Cell Lung Cancer AJCC v7|Stage IA Non-Small Cell Lung Carcinoma AJCC v7|Stage IB Non-Small Cell Lung Carcinoma AJCC v7|Stage II Non-Small Cell Lung Cancer AJCC v7|Stage IIA Non-Small Cell Lung Carcinoma AJCC v7|Stage IIB Non-Small Cell Lung Carcinoma AJCC v7|Stage IIIA Non-Small Cell Lung Cancer AJCC v7
Interventions: OTHER: Laboratory Biomarker Analysis|OTHER: Quality-of-Life Assessment|DRUG: Stereotactic Body Radiation Therapy|DRUG: Stereotactic Body Radiation Therapy|DRUG: Stereotactic Body Radiation Therapy|PROCEDURE: Thoracic Surgical Procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Intraoperative Dexmedetomidine Infusion on Postoperative Bowel Movement in Patients Undergoing Laparoscopic Gastrectomy
Status: COMPLETED
Conditions: Gastric Cancer Patients Undergoing Laparoscopic Gastrectomy
Interventions: DRUG: the dexmedetomidine group|DRUG: the control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Temozolomide 12 Cycles Versus 6 Cycles of Standard First-line Treatment in Patients With Glioblastoma.
Status: COMPLETED
Conditions: Glioblastoma
Interventions: DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Brief Therapies for Problem Gambling Substance Abusers
Status: COMPLETED
Conditions: Gambling
Interventions: BEHAVIORAL: 10 minutes of psycho-education|BEHAVIORAL: 10 minutes of brief advice|BEHAVIORAL: four 50-minute individual therapy sessions of MET & CBT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diagnosis of mTBI in a Community Setting
Status: RECRUITING
Conditions: Traumatic Brain Injury|Mild Traumatic Brain Injury|Brain Injuries|Brain Injuries, Traumatic|Head Injury
Interventions: DEVICE: I-PAS Goggles
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: To Determine Safe and Effective Dose of Sotatercept for the Treatment of Chemotherapy Induced Anemia in Participants With Advanced Non-small Cell Lung Cancer
Status: TERMINATED
Conditions: Anemia|Carcinoma, Non-Small-Cell Lung|Carcinoma, Small-Cell Lung|Bladder Cancer|Cancer of Head and Neck|Uterine Cervical Cancer
Interventions: DRUG: Sotatercept 15 mg|DRUG: Sotatercept 30 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Lactation Study in Women Who Are Breastfeeding or Pumping and Are Receiving Linaclotide Therapeutically
Status: COMPLETED
Conditions: Breast Feeding|Constipation|Irritable Bowel Syndrome
Interventions: DRUG: linaclotide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Safety of Atezolizumab-Bevacizumab in Liver Transplanted Patients With Advanced Hepatocellular Carcinoma
Status: NOT_YET_RECRUITING
Conditions: Liver Transplant|Hepatocellular Carcinoma Recurrent|Systemic Treatment
Interventions: DRUG: Systemic therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing the Use of Dienogest and Combined Oral Contraceptive Pills (Microgynon) to Reduce the Risk of Recurrence of Endometriotic Cyst After Conservative Surgery
Status: UNKNOWN
Conditions: Endometriosis
Interventions: DRUG: Dienogest|DRUG: Microgynon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Efficacy and Safety of Dabigatran Etexilate for the Treatment of Cerebral Venous Thrombosis
Status: UNKNOWN
Conditions: Cerebral Venous Thrombosis
Interventions: DRUG: Dabigatran etexilate|DRUG: Warfarin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Serial Magnetic Resonance Cholangiopancreatography (MRCP) Following Morphine-neostigmine and Secretin Provocation in Healthy Volunteers
Status: COMPLETED
Conditions: Sphincter of Oddi Dysfunction
Interventions: DRUG: Morphine|DRUG: Neostigmine|DRUG: 0.9% saline|DRUG: Secretin|DRUG: 0.9% saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Pharmacokinetic and Bioequivalence Study of Savolitinib Tablets in Healthy Chinese Male Volunteers
Status: COMPLETED
Conditions: Bioequivalence
Interventions: DRUG: Savolitinib Test Preparation|DRUG: Savolitinib Reference Preparation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endovascular Treatment for eXtra-Large Ischemic Stroke
Status: NOT_YET_RECRUITING
Conditions: Stroke, Acute Ischemic
Interventions: DRUG: Medical management|PROCEDURE: Endovascular thrombectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT