pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Effect of Tibial Transcutaneous Electrostimulation in Women With Urgency Urinary Incontinence
Status: RECRUITING
Conditions: Urinary Incontinence, Urge
Interventions: DEVICE: TIBIAL TRANSCUTANEOUS ELECTROSTIMULATION|BEHAVIORAL: behavioral therapy protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Safety and Efficacy of Prosthetic Polymer Heart Valves for the Treatment of Aortic Valve Disease
Status: NOT_YET_RECRUITING
Conditions: Aortic Valve Disease|Aortic Valve Stenosis|Aortic Valve Regurgitation
Interventions: DEVICE: PoliaValve (Aortic)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Drug-Drug Interaction Study To Investigate The Potential For Multiple Doses Of Palbociclib (PD-0332991) To Alter The Pharmacokinetics Of Oral Midazolam In Adult Healthy Women of Non-Childbearing Potential.
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Midazolam|DRUG: PD-0332991|DRUG: Midazolam|DRUG: PD-0332991
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: 68Ga-HA-DOTATATE Imaging of Suspected Somatostatin Receptor Positive Tumors
Status: RECRUITING
Conditions: Neuroendocrine Tumors
Interventions: DRUG: 68Ga-HA-DOTATATE
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of the Safety and Efficacy of Combination Therapy With Morphine, Phenylephrine and Sorbitol in Human Subjects
Status: COMPLETED
Conditions: Acute Pain
Interventions: DRUG: Morphine|DRUG: Morphine|DRUG: Sorbitol+Phenylephrine|DRUG: Sorbitol+Phenylephrine+Morphine|DRUG: Sorbitol low concentration+Phenylephrine+Morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating Levonorgestrel/Ethinyl Estradiol (LNG/EE) in PMS
Status: COMPLETED
Conditions: Premenstrual Syndrome
Interventions: DRUG: Levonorgestrel/Ethinyl Estradiol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Gabapentin to Reduce Postoperative Nausea and Vomiting
Status: COMPLETED
Conditions: Postoperative Nausea and Vomiting
Interventions: DRUG: Gabapentin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: An Open-label Study of the Safety and Pharmacokinetics of the TGKP
Status: NOT_YET_RECRUITING
Conditions: Acute Respiratory Distress Syndrome (ARDS)
Interventions: DRUG: Glycolic acid tetrasubstituted piceatannol (TGKP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Face Masks on Cardiopulmonary Capacity in Healthy Individuals
Status: COMPLETED
Conditions: Covid-19
Interventions: OTHER: without masks|OTHER: Surgical face mask (Vheal Med Co., Ltd., Istanbul, Turkey)|OTHER: FFP2\N95 protective face mask (Musk protective technology, Gaziantep, Turkey)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Femoral Arterial Access With Ultrasound Trial
Status: COMPLETED
Conditions: Vascular Access Complications|Cardiac Catheterization|Peripheral Vascular Disease
Interventions: DEVICE: Real-time Ultrasound Guidance (Site-Rite 5 or 6 machine)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Causal Role of Delta-beta Coupling for Goal-directed Behavior in Anhedonic Depression
Status: RECRUITING
Conditions: Major Depressive Disorder|Anhedonia
Interventions: DEVICE: Delta-beta tACS via the Neurocare Direct Current Stimulator Multi-Channel 4|DEVICE: Theta-gamma tACS via the Neurocare Direct Current Stimulator Multi-Channel 4|DEVICE: Sham tACS via the Neurocare Direct Current Stimulator Multi-Channel 4
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Darbepoetin Trial to Improve Red Cell Mass and Neuroprotection in Preterm Infants
Status: ACTIVE_NOT_RECRUITING
Conditions: Neurocognitive|Neuroprotective|Neonatal|Neurodevelopmental Impairment
Interventions: DRUG: Darbepoetin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bone Marrow Transplantation in Treating Patients With Multiple Myeloma, Chronic Phase Chronic Myelogenous Leukemia, or Agnogenic Myeloid Metaplasia
Status: COMPLETED
Conditions: Chronic Myeloproliferative Disorders|Leukemia|Multiple Myeloma and Plasma Cell Neoplasm
Interventions: DRUG: busulfan|DRUG: cyclophosphamide|PROCEDURE: allogeneic bone marrow transplantation|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Effectiveness of the Universal Prevention Program Super Skills for Life in Schools
Status: RECRUITING
Conditions: Social Skills|Perfectionism|Self Esteem|Positive Affect|Negative Affect|Emotion Regulation|Depressive Symptoms|Anxiety Symptoms|Mood Disorders|Emotional Intelligence
Interventions: BEHAVIORAL: Super Skills Schools
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Bioequivalence Study of Meloxicam Capsules 15 mg (Mobic® Capsules 15 mg) Versus Meloxicam Tablets 15 mg (Mobic® Tablets 15 mg) in Healthy Adult Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Meloxicam capsule|DRUG: Meloxicam tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pre-operative Exercise and Nutrition Therapy on Cardio-metabolic Health in Patients Undergoing Bariatric Surgery
Status: UNKNOWN
Conditions: Bariatric Surgery Candidate
Interventions: BEHAVIORAL: Exercise|PROCEDURE: Standard Care
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Interstitial Brachytherapy for the Treatment of Unresectable/Unablatable Kidney Cancer
Status: RECRUITING
Conditions: Stage I Renal Cell Cancer|Stage II Renal Cell Cancer
Interventions: PROCEDURE: Interstitial Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multicomponent Prehabilitation and Outcomes in Elderly Patients With Frailty
Status: RECRUITING
Conditions: Old Age; Debility|Digestive Cancer|Surgery|Preoperative Rehabilitation|Nutrition Therapy|Outcomes
Interventions: DIETARY_SUPPLEMENT: Preoperative nutritional optimization|BEHAVIORAL: Preoperative exercise training|BEHAVIORAL: Postoperative exercise training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: CGM in Patients With ED's
Status: ENROLLING_BY_INVITATION
Conditions: Anorexia Nervosa Restricting Type|Anorexia Nervosa, Binge Eating/Purging Type|ARFID|Avoidant Restrictive Food Intake Disorder
Interventions: DEVICE: Continuous Glucose Monitor
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Nifty Feeding Cup Versus Generic Medicine Cup Preterm Infants Who Have Difficulty Breastfeeding
Status: COMPLETED
Conditions: Infant,Premature|Feeding; Difficult, Newborn
Interventions: OTHER: Nifty feeding cup|OTHER: Generic medicine cup
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: A Study of Thalidomide Plus Dexamethasone (Thal-Dex) Versus DOXIL plusThalidomide Plus Dexamethasone (DOXIL -Thal-Dex) in Patients With Newly Diagnosed Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Thalidomide|DRUG: Dexamethasone|DRUG: DOXIL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Effect of Vitamin D3 Supplementation on Asthma Symptoms in Adults With Asthma (VITDAS)
Status: COMPLETED
Conditions: Asthma|Vitamin D Deficiency|Nutritional Deficiency|Inflammation
Interventions: DIETARY_SUPPLEMENT: Vitamin D3|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Study to Assess Efficacy and Safety of Cx601, Adult Allogeneic Expanded Adipose-derived Stem Cells (eASC) for the Treatment of Complex Perianal Fistula(s) in Participants With Crohn's Disease (CD)
Status: COMPLETED
Conditions: Crohn's Disease
Interventions: DRUG: Cx601|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ultrasound and Cytological Evaluation 3 Years After Radiofrequency Thermal Ablation of Benign Thyroid Nodules : a Prospective Exploratory Cohort of 180 Nodules
Status: NOT_YET_RECRUITING
Conditions: Thermal Ablation|Fine Needle Aspiration Biopsy|Thyroid Nodules
Interventions: PROCEDURE: Fine needle aspiration biopsy (FNAB)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Comparison of Active and Passive Static Stretching in Delayed Onset of Muscle Soreness of Recreational Body Builders
Status: COMPLETED
Conditions: Sports Physical Therapy
Interventions: OTHER: Active and passive static stretching exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Study to Evaluate Safety and Efficacy of Mirivadelgat in PH-ILD
Status: NOT_YET_RECRUITING
Conditions: Group 3 Pulmonary Hypertension
Interventions: DRUG: Mirivadelgat|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Thoracic Sympathetic Ganglion Block With Botulinum Toxin Type A
Status: NOT_YET_RECRUITING
Conditions: Complex Regional Pain Syndromes
Interventions: DRUG: Botulinum toxin A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigating the Impact of Humiome B2 (Colon Delivered Riboflavin) and Riboflavin-overproducer Probiotic Strain Limosilactobacillus Reuteri AMBV339 on Intestinal and Vaginal Microbiome and Health of Healthy Adult Women (The VIAB2L Project)
Status: RECRUITING
Conditions: Microbial Colonization
Interventions: DIETARY_SUPPLEMENT: Limosilactobacillus reuteri AMBV339|DIETARY_SUPPLEMENT: Humiome B2|DIETARY_SUPPLEMENT: L. reuteri AMBV339 ca. 1x109 CFU per capsule + Humiome B2|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Monoclonal Antibody and Vaccine Therapy in Treating Patients With Stage III or Stage IV Melanoma That Has Been Removed During Surgery
Status: COMPLETED
Conditions: Intraocular Melanoma|Melanoma (Skin)
Interventions: BIOLOGICAL: MART-1 antigen|BIOLOGICAL: gp100 antigen|BIOLOGICAL: incomplete Freund's adjuvant|BIOLOGICAL: ipilimumab|BIOLOGICAL: tyrosinase peptide|PROCEDURE: adjuvant therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Theophylline in Rhinitis
Status: COMPLETED
Conditions: Rhinosinusitis|Asthma|Allergic Rhinitis
Interventions: DRUG: Theophylline (Intervention Group)|DRUG: Placebo (Placebo Group)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Effects of an Intensive Lifestyle Modification Program on Carotid Artery Intima-Media Thickness
Status: COMPLETED
Conditions: a Myocardial Infarction|Coronary Artery Bypass Graft Surgery Percutaneous Transluminal Coronary Angioplasty Stent Placement
Interventions: BEHAVIORAL: Dean Ornish Heart Disease Reversing Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE|Primary Purpose: PREVENTION
Clinical trial: Pathological Findings of Fatal COVID-19
Status: COMPLETED
Conditions: SARS-CoV-2|Covid19|Pathology|Intensive Care Units|Respiratory Distress Syndrome
Interventions: OTHER: 2 post-mortem transcutaneous lung biopsies (1 anterior ; 1 posterior) using anatomical landmarks
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Augmenting Massed Prolonged Exposure With a Stellate Ganglion Block to Treat PTSD
Status: COMPLETED
Conditions: Stress Disorders, Post-Traumatic
Interventions: DRUG: Ropivacaine injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Modulating Repetitive Negative Thinking Related Brain Networks in Young Adults With Depression
Status: RECRUITING
Conditions: Depressive Disorder, Major
Interventions: BEHAVIORAL: Active neurofeedback|BEHAVIORAL: Sham neurofeedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Evaluate the Efficacy of Tolterodine on Specific Symptoms in Adult Patients With Overactive Bladder.
Status: COMPLETED
Conditions: Urinary Bladder, Overactive
Interventions: DRUG: tolterodine extended release
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Prilocaine on Motor Block During Caesarean Section
Status: COMPLETED
Conditions: Spinal for Caesarean Section
Interventions: DRUG: prilocaine|DRUG: bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Pain and Hemodynamics in Peripheral Arterial Disease: Response to Pulsed Electromagnetic Treatment
Status: RECRUITING
Conditions: Peripheral Arterial Disease
Interventions: OTHER: electromagnetic pulsed therapy|OTHER: elliptical exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Controlled Trials Comparing Clinical Outcomes of 3D Versus 2D Laparoscopic Surgery for Gastric Cancer
Status: COMPLETED
Conditions: Stomach Neoplasms
Interventions: PROCEDURE: 3D Laparoscopic Surgery|PROCEDURE: 2D Laparoscopic Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Analgesic Requirement for Post-Operative Pain Control in TLIP Interbody Fusion
Status: ENROLLING_BY_INVITATION
Conditions: Back Pain|Surgery-Complications|Narcotic Use|Physical Stress|Post Operative Pain
Interventions: DRUG: Exparel|DRUG: Bupivacain
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Use of the Amniotic Membrane in Large Wound Epithelialization
Status: COMPLETED
Conditions: Wounds
Interventions: PROCEDURE: Place amniotic membrane in large wounds|PROCEDURE: Obtaining and Cryopreservation of amniotic membrane|DRUG: amniotic membrane
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Consolidation Conventional Radiotherapy + Stereotactic Body Radiotherapy at 3 Months After First-line Chemotherapy in Stage IV Oligometastatic Non-small Cell Lung Cancer
Status: RECRUITING
Conditions: Non-small Cell Lung Cancer
Interventions: RADIATION: primary tumour radiotherapy|RADIATION: stereotactic body radiotherapy|RADIATION: maintenance radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Femaltiker in Stimulation Lactation Among Mothers of Preterm Infants
Status: COMPLETED
Conditions: Lactation Induced
Interventions: OTHER: Femaltiker|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Healing Experiences of Adversity Among Latinos (HEALthy4You)
Status: RECRUITING
Conditions: Stress|Childhood Obesity
Interventions: BEHAVIORAL: Healthy Together (Control)|BEHAVIORAL: Healthy Together + Promotora Support|BEHAVIORAL: Healthy Together + Parenting Training|BEHAVIORAL: Healthy Togethers + Parenting Training + Promotora support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Supplementary Intake of Vitamin D During 12 Weeks Strength Training in Younger and Older People
Status: COMPLETED
Conditions: Muscle Strength|Tendon Elasticity|Muscle CSA|Tendon CSA|VDR Receptor
Interventions: OTHER: 12 weeks Strength exercise training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: NIRAPK : Study of the Relationship(s) Between Clinical, Biological and Pharmacokinetic Metrics and Toxicities When Niraparib is Used as Maintenance Treatment for Ovarian Cancer Patients.
Status: RECRUITING
Conditions: Adult Patients With Platinum-sensitive, Relapsed, High Grade Serous Epithelial Ovarian Cancer
Interventions: BIOLOGICAL: Pharmacokinetics, Dosage of Niraparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Triferic IRIDA (Iron-Refractory Iron-Deficiency Anemia) Protocol
Status: TERMINATED
Conditions: Iron-Refractory Iron-Deficiency Anemia
Interventions: DRUG: Fer-In-Sol|DRUG: Shohl's solution|DRUG: Triferic
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multi-Center Randomised Controlled Study to Evaluate Laparoscopic Versus Open Surgery for Colorectal Cancer
Status: UNKNOWN
Conditions: Colorectal Cancer
Interventions: PROCEDURE: laparoscopic surgery|PROCEDURE: open surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Interferon-Beta-1a (Rebif®) for Treating Subjects With Acute Symptoms of Ulcerative Colitis
Status: COMPLETED
Conditions: Ulcerative Colitis
Interventions: DRUG: Interferon-beta-1a, 44 microgram|DRUG: Placebo|DRUG: Interferon-beta-1a, 66 microgram
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: EASE: The Materna Prep Pivotal Study
Status: RECRUITING
Conditions: Vaginal Delivery|Pelvic Organ Prolapse
Interventions: DEVICE: Materna Prep Device|OTHER: Standard of Care (SOC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Hyoid Displacement During Swallowing Function for Completely Edentulous Subjects
Status: COMPLETED
Conditions: Prosthesis Durability
Interventions: PROCEDURE: implant overdenture|RADIATION: videofluroscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Sofosbuvir Plus Ribavirin, or Ledipasvir/Sofosbuvir in Adults With HCV Infection and Renal Insufficiency
Status: COMPLETED
Conditions: HCV Infection
Interventions: DRUG: SOF|DRUG: RBV|DRUG: LDV/SOF
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Decitabine,Cytarabine and Arsenic Trioxide for Acute Myeloid Leukemia With p53 Mutations
Status: UNKNOWN
Conditions: Acute Myeloid Leukemia|P53 Mutation
Interventions: DRUG: Decitabine|DRUG: Arsenic Trioxide|DRUG: Cytarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of 4-weeks of Motor Relearning Program and Mirror Therapy in Improving Upper Limb Motor Function in Stroke Patients.
Status: ENROLLING_BY_INVITATION
Conditions: Acute Stroke
Interventions: OTHER: motor relearning program|OTHER: mirror therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Bexagliflozin Compared to Glimepiride as Add-on Therapy to Metformin in Type 2 Diabetes Subjects
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Bexagliflozin|DRUG: Placebo for Bexagliflozin|DRUG: Glimepiride|DRUG: Placebo for Glimepiride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study of AZD2171 in Breast Cancer Stage IV (10006202)
Status: COMPLETED
Conditions: Male Breast Cancer|Recurrent Breast Cancer|Stage IV Breast Cancer
Interventions: DRUG: cediranib maleate|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 3-AP and High-Dose Cytarabine in Treating Patients With Advanced Hematologic Malignancies
Status: COMPLETED
Conditions: Accelerated Phase Chronic Myelogenous Leukemia|Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities|Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)|Adult Acute Myeloid Leukemia With t(15;17)(q22;q12)|Adult Acute Myeloid Leukemia With t(16;16)(p13;q22)|Adult Acute Myeloid Leukemia With t(8;21)(q22;q22)|Blastic Phase Chronic Myelogenous Leukemia|Recurrent Adult Acute Lymphoblastic Leukemia|Recurrent Adult Acute Myeloid Leukemia|Relapsing Chronic Myelogenous Leukemia|Secondary Acute Myeloid Leukemia
Interventions: DRUG: cytarabine|DRUG: triapine|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Core Strengthening and Intensive Dynamic Back Exercises in Patient With Low Back Pain
Status: COMPLETED
Conditions: Low Back Pain
Interventions: OTHER: Core strengthening exercise|OTHER: intensive dynamic back exercise|OTHER: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CAlorie and Protein REstriction PROgram in Barrett's Esophagus Patients (CARE-PRO).
Status: COMPLETED
Conditions: Barrett's Esophagus|Overweight and Obesity
Interventions: BEHAVIORAL: Calorie and protein restriction diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of the "Атопик Soothing Cream" in Children With Mild to Moderate Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DEVICE: "Атопик Soothing Cream"|DEVICE: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prucalopride in Pediatric Subjects With Functional Constipation
Status: COMPLETED
Conditions: Functional Constipation
Interventions: DRUG: prucalopride|DRUG: Placebo|DRUG: PEG 4000
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Continuous Non-Invasive and Invasive Intracranial Pressure Measurement
Status: TERMINATED
Conditions: Hydrocephalus|Idiopathic Intracranial Hypertension|Pseudotumor Cerebri
Interventions: DEVICE: Tympanic membrane displacement (TMD)|DEVICE: DPOAE
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of Tai Chi Exercise and Balance in Persons With Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: BEHAVIORAL: Tai Chi|BEHAVIORAL: Strength training|BEHAVIORAL: Low-Impact Exercise Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of The Boosting Effect of Transcranial Random Noise Stimulation (tRNS) in Cognitive Rehabilitation of Patients With Traumatic Brain Injury
Status: UNKNOWN
Conditions: Traumatic Brain Injury|Cognitive Impairment
Interventions: OTHER: Real tRNS|OTHER: Sham tRNS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Determine a Preference for Fluzone Vaccine Given Intradermally (ID) and Intramuscularly (IM) in Healthy Adults
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Fluzone: Influenza virus vaccine|BIOLOGICAL: Fluzone: Influenza virus vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Electroacupuncture Combined With Umbilical Moxibustion on Abdominal Obesity of Yang Deficiency
Status: UNKNOWN
Conditions: Obesity, Abdominal
Interventions: BEHAVIORAL: Electroacupuncture combined with umbilical moxibustion|BEHAVIORAL: Electroacupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PRC-063 Classroom Study in Children (6-12 Years of Age) With ADHD
Status: COMPLETED
Conditions: ADHD
Interventions: DRUG: PRC-063 oral capsules|DRUG: Placebo oral capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Scotoma Perimetry Oculomotor Training
Status: RECRUITING
Conditions: Macular Degeneration|Central Visual Impairment
Interventions: BEHAVIORAL: 'Scotoma awareness' Training|BEHAVIORAL: Control Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: ARrhythmias in MYocarditis
Status: UNKNOWN
Conditions: Myocarditis|Heart Failure|Endomyocardial Biopsy|Arrythmia|Sudden Cardiac Death|Biomarker|Cardiomyopathy
Interventions: DIAGNOSTIC_TEST: ECG holter monitoring
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Assess the Effects of CT-868 Treatment on Glucose Homeostasis in Participants With Type 1 Diabetes
Status: RECRUITING
Conditions: Type 1 Diabetes
Interventions: DRUG: CT-868|DRUG: Placebo|DRUG: Victoza
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Biomarker-Directed, Pembrolizumab (MK-3475) Based Combination Therapy for Advanced Non-Small Cell Lung Cancer (MK-3475-495/KEYNOTE-495)
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Non-Small Cell Lung Cancer
Interventions: BIOLOGICAL: Pembrolizumab|BIOLOGICAL: Favezelimab|DRUG: Lenvatinib|DRUG: Quavonlimab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intervention to Enable Stroke Survivors in Los Angeles County Hospitals to "Stay Within the Guidelines"
Status: COMPLETED
Conditions: Stroke
Interventions: BEHAVIORAL: Care Management|BEHAVIORAL: Written Materials
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effect of Intermittent Oral Tube on Dysphagia in Parkinson's Disease Patients
Status: NOT_YET_RECRUITING
Conditions: Parkinson Disease
Interventions: BEHAVIORAL: Comprehensive rehabilitation training|DEVICE: Intermittent Oro-esophageal Tube|DEVICE: Nasogastric tube
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Autologous Hematopoietic Stem Cell Transplantation for Refractory Multiple Sclerosis
Status: NOT_YET_RECRUITING
Conditions: Multiple Sclerosis
Interventions: PROCEDURE: Autologous haemopoietic stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Discontinuing Renin-angiotensin System Inhibitors in Patients With and Without COVID-19
Status: COMPLETED
Conditions: Covid-19
Interventions: OTHER: Discontinuation of ACEi/ARB|OTHER: Continuation of ACEi/ARB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of Acupuncture in the Prevention of Migraine Without Aura
Status: COMPLETED
Conditions: Migraine Without Aura
Interventions: DEVICE: Verum acupuncture|DEVICE: Sham acupuncture|BEHAVIORAL: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of ASP2138 Given by Itself or Given With Other Cancer Treatments in Adults With Stomach Cancer, Gastroesophageal Junction Cancer, or Pancreatic Cancer
Status: RECRUITING
Conditions: Gastric Adenocarcinoma|Gastroesophageal Junction (GEJ) Adenocarcinoma|Pancreatic Adenocarcinoma
Interventions: DRUG: ASP2138|DRUG: Pembrolizumab|DRUG: Oxaliplatin|DRUG: Leucovorin|DRUG: Fluorouracil|DRUG: Ramucirumab|DRUG: Paclitaxel|DRUG: Irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Psilocybin in Treatment-Resistant Major Depression
Status: ACTIVE_NOT_RECRUITING
Conditions: Treatment-resistant Depression
Interventions: DRUG: Psilocybin|DRUG: Psilocybin|DRUG: Nicotinamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Monopolar Radiofrequency Ablation Using a Dual Switching System and a Separable Clustered Electrode (Octopus®)
Status: COMPLETED
Conditions: HCC|Metastasis
Interventions: DEVICE: DSM|DEVICE: separable clustered electrode
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gemcitabine and Irinotecan in Treating Patients With Cancer of Unknown Primary
Status: COMPLETED
Conditions: Carcinoma of Unknown Primary
Interventions: DRUG: gemcitabine hydrochloride|DRUG: irinotecan hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigational Testing of Bodycad Unicompartmental Knee Prosthesis (UKS)
Status: TERMINATED
Conditions: Osteoarthritis, Knee
Interventions: PROCEDURE: Unicompartmental Knee Arthroplasty Surgery|DEVICE: Bodycad Unicompartmental Knee System (BUKS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Midodrine in the Prevention of Vasovagal Syncope: The Prevention of Syncope Trial IV
Status: ACTIVE_NOT_RECRUITING
Conditions: Vasovagal Syncope
Interventions: DRUG: midodrine hydrochloride|DRUG: matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility of a Multi Site RCT to Establish the Effectiveness of a Health Behaviour Change Intervention for Patients With Peripheral Arterial Disease (PAD).
Status: COMPLETED
Conditions: Health Behavior
Interventions: OTHER: Lifestyle counselling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Study on the Tolerability, Pharmacodynamics and Pharmacokinetics of GST-HG141 Tablets
Status: COMPLETED
Conditions: Hepatitis B
Interventions: DRUG: GST-HG141 tablets|DRUG: Matching Placebos for GST-HG141 tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: EFFICACY OF A MIXTURE OF SIMETHICONE AND TYNDALLIZED BACILLUS COAGULANS IN INFANT COLIC: A PILOT STUDY
Status: COMPLETED
Conditions: Infant Colic
Interventions: COMBINATION_PRODUCT: Mixture of Simethicone and Tyndallized Bacillus Coagulans
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Bioequivalence Study for Acarbose/Metformin FDC
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Acarbose/Metformin FDC(BAY81-9783)|DRUG: Glucobay|DRUG: Glucophage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study of the Scandinavian Total Ankle Replacement (STAR) for the Treatment of Bilateral Degenerative Ankle Disease
Status: COMPLETED
Conditions: Osteoarthritis|Post-Traumatic Arthritis|Rheumatoid Arthritis
Interventions: DEVICE: Scandinavian Total Ankle Replacement (STAR)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dry Eye Symptom Mitigation by Oral Intake of Probiotics
Status: RECRUITING
Conditions: Dry Eye
Interventions: DIETARY_SUPPLEMENT: Probiotics|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Effect of S. Aureus Skin Decolonization on Disease Severity in Atopic Dermatitis Patients
Status: WITHDRAWN
Conditions: Atopic Dermatitis
Interventions: DRUG: Skin Cleanser Combination No.1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Extension Study of Donidalorsen (IONIS-PKK-LRx) in Participants With Hereditary Angioedema
Status: ACTIVE_NOT_RECRUITING
Conditions: Hereditary Angioedema
Interventions: DRUG: Donidalorsen
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rhythmic Risk of Type 1 Brugada Syndrome and Pulmonary Infundibulum Mapping
Status: UNKNOWN
Conditions: Brugada Syndrome Type 1
Interventions: DEVICE: Endocardial mapping
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: CD19-directed CAR-T Cell Therapy for R/R Acute Leukemia and Lymphoma
Status: NOT_YET_RECRUITING
Conditions: Leukemia, Acute Lymphoblastic|Lymphoma, Non-Hodgkin
Interventions: BIOLOGICAL: CART-19
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Analgesic Efficacy of Nefopam in Patients Undergoing Kidney Transplantation
Status: COMPLETED
Conditions: Kidney Transplantation
Interventions: DRUG: Normal saline|DRUG: Nefopam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of the Effects of Different Nutrition Treatments on Patients With Irritable Bowel Syndrome
Status: COMPLETED
Conditions: Irritable Bowel Syndrome
Interventions: OTHER: dietary treatment (low FODMAP)|OTHER: dietary treatment (gluten free)|OTHER: dietary treatment (low FODMAP+gluten free)|OTHER: dietary treatment (Traditional diet recommendations)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics of Oral CK-1827452 in Patients With Stable Heart Failure
Status: COMPLETED
Conditions: Heart Failure
Interventions: DRUG: CK-1827452|DRUG: CK-1827452|DRUG: CK-1827452
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: New Mothers Alpha-Stim
Status: SUSPENDED
Conditions: Anxiety|Depression|Insomnia|Sleep Quality
Interventions: DEVICE: Alpha-Stim AID CES (Active Comparator)|DEVICE: Alpha-Stim AID CES (Sham Comparator)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combined Microneedling With Either 1% Lactic Acid Solution or Vitamin D3 or Triamcinolone Acetonide in The Treatment of Alopecia Areata
Status: RECRUITING
Conditions: Alopecia Areata
Interventions: DRUG: Lactic Acid|DRUG: vit D|DRUG: Triamcinolone Acetonide|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radiotherapy of Head and Neck Cancer Using an Intraoral Stent
Status: RECRUITING
Conditions: Oral Cavity Cancer|Sinonasal Cancer
Interventions: DEVICE: Intraoral stent|OTHER: No intraoral stent
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Amisulpride Augmentation Therapy for Clozapine-resistant Schizophrenic Patients
Status: COMPLETED
Conditions: Treatment-resistant Schizophrenia
Interventions: DRUG: Amisulpride add-on|DRUG: Placebo add-on
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Music-based Treatments and Pain: Underlying Mechanisms and the Beneficial Effects of Music-Based Treatments
Status: RECRUITING
Conditions: Chronic Low-back Pain
Interventions: BEHAVIORAL: Music Therapy|BEHAVIORAL: Music Medicine|BEHAVIORAL: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hyaluronic Acid in Shoulder Tendinopathy
Status: NOT_YET_RECRUITING
Conditions: Shoulder Tendinitis
Interventions: DRUG: Hyaluronic acid injection|DRUG: Corticosteroid injection|DRUG: Placebo injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pan-Asia United States PrEvention of Sudden Cardiac Death Catheter Ablation Trial
Status: COMPLETED
Conditions: Ventricular Tachycardia (VT)
Interventions: DEVICE: Implantable Cardioverter Defibrillator (ICD)|PROCEDURE: Catheter Ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Music Therapy on Families of Burn Patients
Status: TERMINATED
Conditions: Burns
Interventions: BEHAVIORAL: Sound Of Family Together (S.O.F.T.) Music Program|OTHER: Non-Therapy Related Activities (NTRA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation and Implementation of Mobile Tracking Devices to Increase Safety in Hospitalized Patients (MONITOR)
Status: UNKNOWN
Conditions: Fitness Trackers|Hemodynamic Monitoring|Internet of Things|Postoperative Complications|Wearable Electronic Devices|Anesthesia|Surgery
Interventions: DEVICE: Mobile Tracking Device (one spot)|DEVICE: Mobile Tracking Device + Activity Sensor (longitudinal)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: The Clinical Trial of Chidamide+Decitabine+Camrelizumab Versus Decitabine+Camrelizumab in Anti-PD-1 Antibody Resistant Patients With Classical Hodgkin Lymphoma.
Status: RECRUITING
Conditions: Hodgkin Lymphoma|Anti-PD-1 Antibody Resistant
Interventions: DRUG: Chidamide; Decitabine; Camrelizumab|DRUG: Decitabine+Camrelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reproducibility of 18F Uptake by Solid Tumors Using PET Imaging Following Intravenous Administration of (18F) Injection
Status: COMPLETED
Conditions: Solid Tumors|High Grade Gliomas|Lung Cancer|Head and Neck Cancer|Sarcoma|Renal Cell Carcinoma|Breast Cancer
Interventions: DRUG: Fluciclatide Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Dabrafenib and Trametinib Followed by Ipilimumab and Nivolumab or Ipilimumab and Nivolumab Followed by Dabrafenib and Trametinib in Treating Patients With Stage III-IV BRAFV600 Melanoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Clinical Stage III Cutaneous Melanoma AJCC v8|Clinical Stage IV Cutaneous Melanoma AJCC v8|Metastatic Melanoma|Recurrent Melanoma|Unresectable Melanoma
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|DRUG: Dabrafenib Mesylate|PROCEDURE: Echocardiography|BIOLOGICAL: Ipilimumab|PROCEDURE: Multigated Acquisition Scan|BIOLOGICAL: Nivolumab|OTHER: Quality-of-Life Assessment|DRUG: Trametinib Dimethyl Sulfoxide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of CaBozantinib in Patients With Advanced or Unresectable Renal cEll cArcinoma
Status: COMPLETED
Conditions: Metastatic Renal Cell Carcinoma
Interventions: DRUG: Cabometyx
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigating Botulinum Toxin A to Treat Acute Neck/Upper Shoulder Pain Following a New Spinal Cord Injury.
Status: COMPLETED
Conditions: Spinal Cord Injury|Pain
Interventions: DRUG: botulinum toxin A|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Single-arm, Multicenter Clinical Study of Fruquintinib Combined With Cadonilimab Injection and Temozolomide in Second-line and Subsequent Treatment of Advanced Melanoma
Status: NOT_YET_RECRUITING
Conditions: Malignant Melanoma
Interventions: DRUG: Temozolomide、Fruquintinib、Cadonilimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intravenous NAC Use in ACLF Patients
Status: UNKNOWN
Conditions: Acute on Chronic Liver Failure(ACLF)
Interventions: DRUG: N acetyl cysteine|DRUG: Placebo of N acetyl cysteine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Effectiveness of Virtual Reality and Video Assisted Exercises in Pediatric Chronic Kidney Disease.
Status: COMPLETED
Conditions: Pediatric Kidney Disease|Physical Activity|Exercise Addiction
Interventions: OTHER: study group|OTHER: control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigation of the Clinical Safety and Efficacy of Long-term Treatment With Fycompa Tablets in Adolescence Epilepsy Patients With Partial-onset Seizures (With or Without Secondary Generalized Seizures) or Primary Generalized Tonic-clonic Seizures
Status: COMPLETED
Conditions: Partial Seizures (With or Without Secondary Generalized Seizures)|Primary Generalized Tonic-clonic Seizures
Interventions: DRUG: Fycompa
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Analgesic Efficacy of Two Bupivacaine Concentrations for Combined Ilioinguinal and Iliohypogastric Nerve Block in Postherniorrhaphy Pain
Status: NOT_YET_RECRUITING
Conditions: Hernia, Inguinal
Interventions: DRUG: Bupivacaine|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Effectiveness of Early Physical Therapy Versus Usual Care for Low Back Pain
Status: COMPLETED
Conditions: Low Back Pain
Interventions: PROCEDURE: Usual Care (UC)|PROCEDURE: Early Physical Therapy (PT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT