pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Pregnancy Rate After Unilateral Tubal Disconnection
Status: RECRUITING
Conditions: Pregnancy Rate
Interventions: PROCEDURE: Unilateral tubal disconnection + Spontaneous follow up for pregnancy|PROCEDURE: Unilateral tubal disconnection + ICSI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Cannabinoid Supplementation on Vascular and Cognitive Function
Status: UNKNOWN
Conditions: Diet Modification
Interventions: DIETARY_SUPPLEMENT: Cannabidiol supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluating the Impact of the McMaster Optimal Aging Portal on Cancer Prevention Behaviours in Underserved Populations
Status: COMPLETED
Conditions: Cancer
Interventions: BEHAVIORAL: Tailored knowledge translation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Human C1 Esterase Inhibitor (C1-INH) in Subjects With Acute Abdominal or Facial Hereditary Angioedema (HAE) Attacks
Status: COMPLETED
Conditions: Hereditary Angioedema
Interventions: BIOLOGICAL: C1 Esterase Inhibitor|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of VoLumen and Breeza Oral Contrast Agents in Pediatric Patients
Status: COMPLETED
Conditions: Inflammatory Bowel Diseases
Interventions: OTHER: Barium Sulfate|OTHER: Flavored beverage Oral Contrast
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Prospective Randomized Controlled Trial of Impact of Enhanced Recovery After Surgery(ERAS) for Outcomes of Total Knee and Hip Arthroplasty
Status: UNKNOWN
Conditions: Arthroplasty, Replacement, Knee, Hip
Interventions: OTHER: Enhanced recovery after surgery (ERAS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pregabalin Compared to Gabapentin for Pain Control in Lumbar Disc Surgery
Status: COMPLETED
Conditions: Intervertebral Disc Prolapse
Interventions: DRUG: Pregabalin|DRUG: Gabapentin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of BF2.649 in the Treatment of Excessive Daytime Sleepiness in Narcolepsy.
Status: COMPLETED
Conditions: Treatment of Excessive Daytime Sleepiness in Narcolepsy
Interventions: DRUG: BF2.649|DRUG: Vigil|DRUG: palcebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective, Randomized, Parallel Clinical Controlled Study of Early Diet Opening on Postoperative Gastrointestinal Hemorrhage in Patients With Colonic Polyps
Status: UNKNOWN
Conditions: Colonic Polyp
Interventions: DIETARY_SUPPLEMENT: Early diet opening
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: High-definition tDCS Treatment for Cantonese-speaking Adults Who Stutter
Status: COMPLETED
Conditions: Stuttering, Adult|Stammering
Interventions: DEVICE: Active-tDCS|DEVICE: Sham-tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of APG2575 Single Agent and Combination Therapy in Patients With Relapsed/Refractory CLL/SLL
Status: RECRUITING
Conditions: Chronic Lymphocytic Leukemia|Small Lymphocytic Lymphoma
Interventions: DRUG: APG-2575|DRUG: Rituximab|DRUG: Ibrutinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Nursing Care Based on Kolcaba's Comfort Theory on of Intensive Care Patients
Status: COMPLETED
Conditions: Critical Care|Patient Satisfaction
Interventions: OTHER: Nursing Care Based on Kolcaba's Comfort Theory
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Chronic Effect of Fasting
Status: RECRUITING
Conditions: Overweight and Obesity
Interventions: BEHAVIORAL: Caloric restriction only|BEHAVIORAL: Caloric restriction plus TRF morning|BEHAVIORAL: Caloric restriction plus TRF night
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Mini Implant Supported Appliance and Headgear in Treatment of Maxillary Excess in Growing Patients
Status: UNKNOWN
Conditions: Class II Division 1 Malocclusion
Interventions: DEVICE: Infra-zygomatic Mini Implant Supported Appliance|DEVICE: high pull head gear
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Influence of the Surgical Technique Used for Colectomies on the Concentration of Circulating Tumor DNA and the Presence of Circulating Tumor Cells: Comparison of the "no Touch" Technic With Either First Clamping of the Mesenteric Vessels or First Mobilization of the Tumor Followed by Clamping.
Status: UNKNOWN
Conditions: Colorectal Cancer
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: FOLFOX Plus SIR-SPHERES MICROSPHERES Versus FOLFOX Alone in Patients With Liver Mets From Primary Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer|Colorectal Carcinoma|Liver Metastases
Interventions: DEVICE: SIR-Spheres yttrium-90 microspheres|DRUG: Systemic chemotherapy (FOLFOX)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Danirixin (GSK1325756) Inhibition of CD11b Cell Surface Expression
Status: COMPLETED
Conditions: Infections, Respiratory Syncytial Virus
Interventions: DRUG: Danirixin|OTHER: CXCL1
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Antibiotic Prophylaxis in Mesh Repair of Inguinal Hernias
Status: COMPLETED
Conditions: Inguinal Hernia
Interventions: DRUG: sefazolin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Yoga in Improving Quality of Life in Patients With Non-small Cell Lung Cancer Undergoing Treatment
Status: TERMINATED
Conditions: Non-small Cell Lung Cancer|Recurrent Non-Small Cell Lung Carcinoma
Interventions: BEHAVIORAL: Yoga|BEHAVIORAL: Support Group Therapy|OTHER: FACT-L|OTHER: Pulmonary function test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Allogeneic Islet Cells Transplanted Onto the Omentum
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus|Hypoglycemia|Hypoglycemia Unawareness
Interventions: BIOLOGICAL: Islet transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of LY2584702 With Erlotinib or Everolimus in Participants With Solid Tumors
Status: TERMINATED
Conditions: Metastases, Neoplasm|Carcinoma, Non-small Cell Lung|Renal Cell Carcinoma|Neuroendocrine Tumors
Interventions: DRUG: LY2584702|DRUG: Erlotinib|DRUG: Everolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Compare Vinorelbine In Combination With the mTOR Inhibitor Everolimus vs. Vinorelbin Monotherapy for Second-line Treatment in Advanced Breast Cancer
Status: COMPLETED
Conditions: Her2-negative Metastatic Breast Cancer|Her2-negative Locally Advanced Breast Cancer
Interventions: DRUG: Vinorebine, Everolimus|DRUG: Vinorelbine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of KITE-363 or KITE-753 in Participants With Relapsed and/or Refractory B-cell Lymphoma
Status: RECRUITING
Conditions: Relapsed and/or Refractory B-cell Lymphoma
Interventions: DRUG: Cyclophosphamide|DRUG: Fludarabine|BIOLOGICAL: KITE-363|BIOLOGICAL: KITE-753
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Post-Marketing Safety Study of Menactra® in Healthy Children, Adolescents, and Adults in the Philippines
Status: COMPLETED
Conditions: Meningitis|Meningococcal Disease
Interventions: BIOLOGICAL: Menactra®: Meningococcal Polysaccharide Diphtheria Toxoid Conjugate|BIOLOGICAL: Menactra®: Meningococcal Polysaccharide Diphtheria Toxoid Conjugate|BIOLOGICAL: Menactra®: Meningococcal Polysaccharide Diphtheria Toxoid Conjugate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Chemotherapy With or Without Bevacizumab or Lapatinib to Treat Operable Oesophagogastric Cancer
Status: UNKNOWN
Conditions: Oesophagogastric Cancer
Interventions: BIOLOGICAL: bevacizumab|DRUG: capecitabine|DRUG: cisplatin|DRUG: Epirubicin|PROCEDURE: adjuvant therapy|PROCEDURE: conventional surgery|PROCEDURE: neoadjuvant therapy|DRUG: Lapatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study on the Bioavailability of Three Different Prescription Processes of SHR4640 Tablets in Healthy Volunteers
Status: UNKNOWN
Conditions: Primary Gout|Hyperuricemia
Interventions: DRUG: SHR4640
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: ACT-20 in Patients With Severe COVID-19 Pneumonia
Status: UNKNOWN
Conditions: COVID-19 Pneumonia
Interventions: BIOLOGICAL: ACT-20-MSC|BIOLOGICAL: ACT-20-CM|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Single Dose Trial in Growth Hormone Deficient Children Investigating Safety, Pharmacokinetics and Pharmacodynamics of Long Acting Growth Hormone
Status: COMPLETED
Conditions: Growth Hormone Disorder|Growth Hormone Deficiency in Children
Interventions: DRUG: NNC126-0083|DRUG: somatropin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Safety, Tolerability and Effectiveness of EZM0414 Investigative Product in Participants With Relapsed/Refractory Multiple Myeloma and Relapsed/Refractory Diffuse Large B Cell Lymphoma
Status: RECRUITING
Conditions: Multiple Myeloma, Refractory|Diffuse Large B-Cell Lymphoma|Diffuse Large B Cell Lymphoma Refractory|Multiple Myeloma in Relapse
Interventions: DRUG: EZM0414
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exercise as a Life-long Medicine in Patients With Coronary Artery Disease
Status: COMPLETED
Conditions: Cardiovascular Diseases|Myocardial Infarction|Angina (Stable)
Interventions: BEHAVIORAL: high-intensity exercise training|BEHAVIORAL: web-based follow-up program|BEHAVIORAL: usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing the Effectiveness and Costs of Bevacizumab to Ranibizumab in Patients With Retinal Vein Occlusions (BRVO)
Status: UNKNOWN
Conditions: Retinal Vein Occlusion
Interventions: DRUG: Bevacizumab|DRUG: Ranibizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Internal and External Micro-needling in Treatment of Stage III Periodontitis
Status: NOT_YET_RECRUITING
Conditions: Periodontal Diseases
Interventions: DEVICE: external microneedling|OTHER: minimally invasive non- surgical periodontal therapy|DEVICE: internal micro_needling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ACTHAR GEL for Sarcoidosis-Associated Calcium Dysregulation: An Open-label Pilot Study
Status: UNKNOWN
Conditions: Sarcoidosis|Hypercalcemia Due to Sarcoidosis
Interventions: DRUG: ACTHAR Gel (adrenocorticotropic hormone)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sex Differences in Trauma, Inflammation and Brain Function and the Implications for Treatment Efficacy in Alcohol Use Disorder
Status: RECRUITING
Conditions: Alcohol Use Disorder
Interventions: DRUG: Naltrexone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of CM310 in Patients With Uncontrolled Seasonal Allergic Rhinitis
Status: NOT_YET_RECRUITING
Conditions: Seasonal Allergic Rhinitis
Interventions: BIOLOGICAL: Interleukin-4 receptor responders|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Interbody Cage Insertion in Treatment of Lumbar Disc Prolapse
Status: UNKNOWN
Conditions: Lumbar Disc Herniation
Interventions: PROCEDURE: Interbody cage insertion in lumbar disc prolapse
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Use of a Bearable Continuous Interstitial Glucose Monitoring Device (GuardianR) During Teaching Sessions to Functional Insulin Therapy Concept in Patients Suffering From Type 1 Diabetes: Evaluation at 6 and 12 Months
Status: COMPLETED
Conditions: Diabetes Complications
Interventions: DEVICE: GuardianR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation of Soy-protein Russian Tarragon (Artemisia Dracunculus L.)
Status: COMPLETED
Conditions: Diabetes Prevention
Interventions: DIETARY_SUPPLEMENT: Dose 1|DIETARY_SUPPLEMENT: Dose 2|DIETARY_SUPPLEMENT: Dose 0|DIETARY_SUPPLEMENT: Dose 3|DIETARY_SUPPLEMENT: Dose 4|DIETARY_SUPPLEMENT: Dose 5|DIETARY_SUPPLEMENT: Dose 6
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Understand the Usage of an Artificial Intelligence Technology Called DARWEN for Eye Disorders and to Find Out the Factors Influencing Treatment Frequencies in People With nAMD and RVO
Status: COMPLETED
Conditions: Neovascular Age-related Macular Degeneration|Retinal Vein Occlusion
Interventions: DRUG: anti-VEGF treatment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Nivolumab Plus Axitinib in Patients With Anti-PD1 Refractory Advanced Melanoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Melanoma|Unresectable Melanoma
Interventions: DRUG: Nivolumab|DRUG: Axitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Disability of Musculoskeletal Origin in Community-dwelling Elderly
Status: COMPLETED
Conditions: Musculoskeletal Diseases
Interventions: PROCEDURE: Specific clinical care program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Multimodal Cue Exposure Therapy for Smoking Cessation
Status: WITHDRAWN
Conditions: Smoking Cessation
Interventions: DRUG: D-Cycloserine|DRUG: Placebo oral tablet|BEHAVIORAL: Open Phase CBT that preceeds the randomization phase|DRUG: Open phase smoking cessation pharmacotherapy that proceeds the randomization phase
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pediatric Arthritis Study of Certolizumab Pegol
Status: COMPLETED
Conditions: Polyarticular-course Juvenile Idiopathic Arthritis (JIA)
Interventions: DRUG: Certolizumab Pegol (CZP)|DRUG: Certolizumab Pegol (CZP)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: OPTAMISE: Clinical Effectiveness of Teriparatide After Alendronate or Risedronate Therapy in Osteoporotic Postmenopausal Women
Status: COMPLETED
Conditions: Osteoporosis, Postmenopausal
Interventions: DRUG: risedronate sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hepatic Arterial Infusion of Oxaliplatin and Fluorouracil Treatment of Advanced Primary Liver Cancer After TACE
Status: UNKNOWN
Conditions: Advanced Adult Primary Liver Cancer
Interventions: DRUG: Oxaliplatin and fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of DSP-7888 Dosing Emulsion in Combination With Bevacizumab in Patients With Recurrent or Progressive Glioblastoma Following Initial Therapy
Status: COMPLETED
Conditions: Glioblastoma
Interventions: DRUG: DSP-7888 Dosing Emulsion|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study on the Efficacy of Long-term Drainage of Subdural Effusion After Decompressive Craniectomy
Status: NOT_YET_RECRUITING
Conditions: Traumatic Brain Injury|Decompressive Craniectomy|Subdural Effusion
Interventions: PROCEDURE: Long-term Drainage|PROCEDURE: Short-term Drainage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Durvalumab Plus Chemotherapy in Untreated Patients With Extensive-Stage Small Cell Lung Cancer
Status: COMPLETED
Conditions: Small Cell Lung Carcinoma Extensive Disease
Interventions: DRUG: Durvalumab|DRUG: Cisplatin|DRUG: Etoposide|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Study With Colchicine in Healthy Volunteers
Status: COMPLETED
Conditions: Pharmacokinetics
Interventions: DRUG: colchicine tablets|DRUG: colchicine tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of Efficacy of Intravenous Paracetamol and Dexketoprofen for Acute Traumatic Musculoskeletal Pain
Status: COMPLETED
Conditions: Musculoskeletal Pain
Interventions: DRUG: Paracetamol|DRUG: Dexketoprofen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Blue-light Blocking Lens on Visual Functions
Status: COMPLETED
Conditions: Effects of Blue-light Blocking Lens on Visual Functions
Interventions: DEVICE: clear lens with regular coating|DEVICE: regular coating lens with yellow tint|DEVICE: clear lens with blue-light blocking coating
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Study of Capecitabine and Cyclophosphamide Administered as a Single Pill in Patients With Advanced Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer Metastatic
Interventions: DRUG: Fixed-dose combination of capecitabine and cyclophosphamide SAR439281
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Levocarnitine for Dry Eye in Sjogren's Syndrome
Status: RECRUITING
Conditions: Sjogren's Syndrome|Keratoconjunctivitis Sicca
Interventions: DRUG: Levocarnitine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prototype DAA/TAA Vaccine Targeting MUC1 for Immune Interception and Prevention in Ductal Carcinoma In Situ
Status: RECRUITING
Conditions: Ductal Carcinoma in Situ
Interventions: BIOLOGICAL: MUC1 Peptide Vaccine|DRUG: Hiltonol®|DRUG: Aromatase Inhibitor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mitomycin and Mitoxantrone in Treating Patients With Acute Myelogenous Leukemia
Status: COMPLETED
Conditions: Leukemia
Interventions: BIOLOGICAL: sargramostim|DRUG: mitomycin C|DRUG: mitoxantrone hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Anticoagulation Profile in Pregnant Women Treated With Three Times a Day of Low Molecular Weight Heparin (LMWH)
Status: RECRUITING
Conditions: Pregnancy, High Risk|Anticoagulants
Interventions: DRUG: Lovenox
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Music Genre Stereotypes to Boost Relaxation in Chronic Pain Patients
Status: NOT_YET_RECRUITING
Conditions: Anxiety
Interventions: BEHAVIORAL: Listening to Reggae Music and told the stereotype|BEHAVIORAL: Listening to Nature Sounds
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of MabThera (Rituximab) Addition to Regularly Prescribed Chemotherapy in Patients With Untreated Mantle Cell Lymphoma.
Status: TERMINATED
Conditions: Diffuse Large B-Cell Lymphoma
Interventions: DRUG: Cyclophosphamide|DRUG: Fludarabine|DRUG: Mitoxantrone|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Plant Stanol Esters and Preventing Asthma Symptoms
Status: RECRUITING
Conditions: Asthma, Allergic|Cardiovascular Diseases
Interventions: DIETARY_SUPPLEMENT: Soft chews containing 0.5g plant stanols (delivered as plant stanol esters)|DIETARY_SUPPLEMENT: Placebo soft chew
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of Dasatinib in Chronic Phase Philadelphia Chromosome Positive Chronic Myeloid Leukemia
Status: COMPLETED
Conditions: Myeloid Leukemia, Chronic
Interventions: DRUG: Dasatinib|DRUG: dasatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of New Ostomy Devices in Subjects Having an Ileostomy
Status: COMPLETED
Conditions: Ileostomy - Stoma
Interventions: DEVICE: SenSura Mio|DEVICE: Coloplast Ostomy device 1|DEVICE: Coloplast Ostomy device|DEVICE: Coloplast Ostomy device 3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Afatinib, Paclitaxel, 2nd Line, Advanced Gastric Cancer
Status: COMPLETED
Conditions: Gastric Cancer|Gastroesophageal Junction Cancer
Interventions: DRUG: afatinib|DRUG: paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Patient-operated Valved Catheter Versus Indwelling Transurethral Catheter
Status: COMPLETED
Conditions: Bladder Dysfunction|Urinary Retention
Interventions: DEVICE: Bladder catheter: OPTION-vf patient controlled catheter vs. indwelling transurethral catheter with leg bag|DEVICE: Transurethral catheter with leg bag
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Irinotecan and 5 FU/FA To 5-FU/FA After Resection Of Liver Metastases For Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Neoplasms|Liver Neoplasms
Interventions: DRUG: Irinotecan + 5 FU + folinic acid|DRUG: Folinic Acid + 5 FU
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intrauterine Embryo Development With ANECOVA Device
Status: TERMINATED
Conditions: Healthy
Interventions: DEVICE: in vivo (ANECOVA D-1) or in vitro culture in 25-µl droplets of cleavage medium (Medicult®) under paraffin oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: ARTEMIS Peanut Allergy In Children
Status: COMPLETED
Conditions: Peanut Allergy
Interventions: BIOLOGICAL: AR101 powder provided in capsules & sachets|OTHER: Placebo powder provided in capsules & sachets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bioavailability of the Fixed Combination of Amodiaquine and Artesunate Under Fed & Fasted Conditions
Status: COMPLETED
Conditions: Malaria
Interventions: DRUG: Artesunate + Amodiaquine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Offset Analgesia as a Measure of Central Sensitization in Children
Status: COMPLETED
Conditions: Chronic Pain Syndrome|Chronic Daily Headache|Functional Abdominal Pain Syndrome|Musculoskeletal Pain Disorder|CRPS (Complex Regional Pain Syndromes)
Interventions: OTHER: Offset analgesia
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: A Study to Evaluate the Lipid Regulating Effects of TRIA-662
Status: COMPLETED
Conditions: Hyperlipidemia
Interventions: DRUG: Low Dose TRIA-662|DRUG: High Dose TRIA-662|DRUG: Placebo for TRIA-662
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Standardized-propolis Extract (EPP-AF®) Gel Formulation as Buccal Antiseptic
Status: COMPLETED
Conditions: Candidiasis, Oral|Stomatitis, Denture
Interventions: OTHER: Propolis|DRUG: Miconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Efficacy of Oxfendazole Compared to Albendazole in the Treatment of Trichuris Trichiura Infection in Adults
Status: WITHDRAWN
Conditions: Helminthiasis
Interventions: DRUG: oxfendazole|DRUG: albendazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial to Evaluate Safety, Tolerability and Pharmacokinetic/Pharmacodynamic Characteristics of KMRC011
Status: COMPLETED
Conditions: Acute Radiation Syndrome
Interventions: DRUG: KMRC011 5μg or Placebo|DRUG: KMRC011 10μg or Placebo|DRUG: KMRC011 15μg or Placebo|DRUG: KMRC011 20μg or Placebo|DRUG: KMRC011 25μg or Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Screening for Subclinical Antibody Mediated Rejection and Efficacy of Belatacept in the Context of de Novo Donor Specific Antibody After Kidney Transplantation (BELA-M-R)
Status: NOT_YET_RECRUITING
Conditions: Kidney Transplant Rejection
Interventions: DRUG: Conversion to Belatacep|DRUG: Standard of care treatment (SOC regimen) with Tacrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neuroinflammation and Age-associated Brain Pathology: Two Potential Mechanisms of Cognitive Impairment in Ovarian Cancer
Status: WITHDRAWN
Conditions: Ovarian Cancer
Interventions: DRUG: [11C]PiB and 18F-labeled DPA-714 PET scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Transplantation for Patients With Chronic Lymphocytic Leukemia
Status: COMPLETED
Conditions: Leukemia, Lymphocytic, Chronic
Interventions: PROCEDURE: high dose chemotherapy then autologous hematopoietic cell transplant|PROCEDURE: ablative allogeneic hematopoietic cell transplant
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Circum-Psoas Blocks Versus Combined Lumbar and Sacral Plexus Blocks in Hip Fracture Surgery
Status: RECRUITING
Conditions: Hip Fractures
Interventions: OTHER: control|PROCEDURE: LSP|PROCEDURE: CP|DEVICE: Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Phase II Study of the Combination of Ponatinib With Mini-hyper CVD Chemotherapy and Venetoclax in Patients With Relapsed or Refractory T-cell Acute Lymphoblastic Leukemia
Status: RECRUITING
Conditions: Acute Lymphoblastic Leukemia|Leukemia
Interventions: DRUG: Ponatinib|DRUG: Venetoclax|DRUG: Mini-hyper CVD
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fluorescence and Reflectance Spectroscopy During Colposcopy in Detecting Cervical Intraepithelial Neoplasia and Dysplasia in Healthy Participants With a History of Normal Pap Smears
Status: COMPLETED
Conditions: Cervical Cancer|Precancerous Condition
Interventions: PROCEDURE: Colposcopic biopsy|PROCEDURE: Light-Scattering Spectroscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Anthology Hip Replacement System - Orthopaedic Data Evolution Panel (ODEP) Surveillance Study
Status: COMPLETED
Conditions: Primary Osteoarthritis|Secondary Osteoarthritis|Avascular Necrosis|Primary Total Hip Replacement (THR)
Interventions: DEVICE: Anthology Hip Replacement System
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Intervention by Midwife to Address the Fear of Childbirth
Status: COMPLETED
Conditions: Fear of Childbirth
Interventions: BEHAVIORAL: Online prenatal specific education|BEHAVIORAL: Intrapartum specific support|BEHAVIORAL: Prenatal usual education|BEHAVIORAL: Intrapartum usual support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Change in Management Following Bronchoscopy in Hematopoietic Stem Cell Transplant Patients With Pulmonary Infiltrates
Status: COMPLETED
Conditions: Stem Cell Transplant Complications|Pulmonary Complication
Interventions: PROCEDURE: Fiberoptic Bronchoscopy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phase II Study of Pazopanib as Second-line Treatment After Sunitinib in mRCC Patients
Status: UNKNOWN
Conditions: Self Efficacy|Adverse Drug Event|Carcinoma, Renal Cell
Interventions: DRUG: pazopanib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Skeletal Muscle Expression of Myostatin and Cancer of Digestive System Associated Cachexia
Status: TERMINATED
Conditions: Cancer of Digestive System
Interventions: DIAGNOSTIC_TEST: Height and weight|DIAGNOSTIC_TEST: Blood samples|DIAGNOSTIC_TEST: Skeletal muscle force|DIAGNOSTIC_TEST: Skeletal muscle index|DIAGNOSTIC_TEST: Muscle biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Relapsed/Refractory Large B-cell Lymphoma With NT-I7 Post-CD19 CAR T-cell Therapy
Status: RECRUITING
Conditions: Refractory Diffuse Large B-cell Lymphoma|Refractory Diffuse Large B-Cell Lymphoma, Not Otherwise Specified|Recurrent Diffuse Large B-Cell Lymphoma|Refractory High Grade B-Cell Lymphoma|Refractory Transformed Follicular Lymphoma to Diffuse Large B-Cell Lymphoma
Interventions: DRUG: Efineptakin alfa|DRUG: Tisagenlecleucel|DRUG: Axicabtagene ciloleucel|DRUG: Lisocabtagene Maraleucel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A 44-week Monocentric Open Study Assessing the Efficacy and Safety of Deucravacitinib in Adults With Inflammatory Genodermatoses
Status: NOT_YET_RECRUITING
Conditions: Inflammatory Epidermal Genodermatoses
Interventions: DRUG: deucravacitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SarCaBon: A Randomised Phase II Trial of Saracatinib Versus Placebo for Cancer-induced Bone Pain
Status: COMPLETED
Conditions: Cancer
Interventions: DRUG: Saracatinib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Acute Congestive Heart Failure
Status: UNKNOWN
Conditions: Acute Decompensated Heart Failure (ADHF)|Acute Cardiogenic Pulmonary Edema (ACPE)
Interventions: DEVICE: non-invasive respiratory parameter measurements
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Trial to Evaluate Safety and Efficacy of Treatment of Physician Choice (TPC) Following First-Line Treatment of Lenvatinib in Subjects With Unresectable Hepatocellular Carcinoma (uHCC)
Status: TERMINATED
Conditions: Carcinoma, Hepatocellular
Interventions: DRUG: Lenvatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: NS-089/NCNP-02-201 in Boys With Duchenne Muscular Dystrophy (DMD)
Status: RECRUITING
Conditions: Duchenne Muscular Dystrophy
Interventions: DRUG: NS-089/NCNP-02
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adipose Mesenchymal Cells for Abatement of SARS-CoV-2 Respiratory Compromise in COVID-19 Disease
Status: NOT_YET_RECRUITING
Conditions: Covid-19 Pneumonia|Cyotokine Storm
Interventions: BIOLOGICAL: Autologous Adipose MSC's
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Luteal Phase Support With GnRH Agonist After GnRH Agonist Triggering in IVF/ICSI Cycles
Status: NOT_YET_RECRUITING
Conditions: In Vitro Fertilization|ICSI Intracytoplasmic Spermatozoid Injection
Interventions: DRUG: Ovulation induction with hCG + Luteal phase support with vaginal progesterone|DRUG: Ovulation triggering by Triptorelin + Luteal phase support by Nafarelin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Decision Support Following Genetic Testing for Breast-Ovarian Cancer Susceptibility
Status: COMPLETED
Conditions: Breast Cancer|Ovarian Cancer
Interventions: BEHAVIORAL: Enhanced Internet DA|BEHAVIORAL: Internet DA|BEHAVIORAL: Enhanced Print DA|BEHAVIORAL: Print DA|BEHAVIORAL: Inconclusive Results DA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: PENG Block in Comparison With FICB for Hip Reconstruction in Children
Status: RECRUITING
Conditions: Perioperative Analgesia|Hip Dislocation, Developmental
Interventions: PROCEDURE: Pericapcelar group nerve block|PROCEDURE: Fascia iliaca compartment block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A 3-Part, Open-Label, Drug-Drug Interaction Study of Concomitant Administration of E2609 With Itraconazole, Rifampin, Digoxin, or Donepezil
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: E2609|DRUG: itraconazole|DRUG: rifampin|DRUG: digoxin|DRUG: donepezil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Methylphenidate for Attention Deficit Hyperactivity Disorder and Autism in Children
Status: COMPLETED
Conditions: Autism|Attention Deficit Disorder With Hyperactivity
Interventions: DRUG: Methylphenidate-extended release|DRUG: Methylphenidate-immediate release|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of a Corrie Cardiac Rehabilitation Program
Status: RECRUITING
Conditions: Coronary Artery Disease|Myocardial Infarction|Myocardial Ischemia|Coronary Artery Occlusion|Coronary Artery Stenosis Stent|Bypass Graft Occlusion|Valve Heart Disease
Interventions: COMBINATION_PRODUCT: Corrie Hybrid Cardiac Rehabilitation Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Chemotherapy, With or Without Binimetinib in Advanced Biliary Tract Cancers in 2nd Line Setting (A ComboMATCH Treatment Trial)
Status: RECRUITING
Conditions: Recurrent Biliary Tract Carcinoma|Recurrent Distal Cholangiocarcinoma|Recurrent Gallbladder Carcinoma|Recurrent Intrahepatic Cholangiocarcinoma|Stage III Distal Bile Duct Cancer AJCC v8|Stage III Hilar Cholangiocarcinoma AJCC v8|Stage III Intrahepatic Cholangiocarcinoma AJCC v8|Stage IV Distal Bile Duct Cancer AJCC v8|Stage IV Hilar Cholangiocarcinoma AJCC v8|Stage IV Intrahepatic Cholangiocarcinoma AJCC v8|Unresectable Biliary Tract Carcinoma|Unresectable Distal Cholangiocarcinoma|Unresectable Gallbladder Carcinoma|Unresectable Intrahepatic Cholangiocarcinoma
Interventions: DRUG: Binimetinib|PROCEDURE: Biopsy|PROCEDURE: Biospecimen Collection|PROCEDURE: Bone Scan|PROCEDURE: Computed Tomography|PROCEDURE: Echocardiography|DRUG: Fluorouracil|DRUG: Leucovorin Calcium|PROCEDURE: Magnetic Resonance Imaging|PROCEDURE: Multigated Acquisition Scan|DRUG: Oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Surgical and Endovascular Arteriovenous Fistula Creation
Status: NOT_YET_RECRUITING
Conditions: End Stage Renal Disease on Dialysis
Interventions: DEVICE: endoAVF|PROCEDURE: surgAVF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intervention Development for Syndemics Among PWH in SA
Status: NOT_YET_RECRUITING
Conditions: HIV Infections
Interventions: BEHAVIORAL: Cognitive Behavioral Therapy for Syndemics and Adherence (CBT-SA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Physical Therapy in Women With Interstitial Cystitis
Status: COMPLETED
Conditions: Interstitial Cystitis|Painful Bladder Syndrome
Interventions: OTHER: Global Therapeutic Massages (GTM)|OTHER: Myofascial Tissue Manipulation (MTM)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Effects of TFPB and Anterior QLB on Postoperative Analgesia in Cesarean Section Surgery
Status: COMPLETED
Conditions: Analgesia|Acute Pain|Chronic Pain
Interventions: OTHER: Regional anesthesia TFPB|OTHER: Regional anesthesia QLB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Open Label Phase Two Trial of Radium Ra 223 Dichloride With Concurrent Administration of Abiraterone Acetate Plus Prednisone in Symptomatic Castration-Resistant (Hormone-Refractory) Prostate Cancer Subjects With Bone Metastasis
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: Concurrent use of Radium Ra 223 dichloride and Abiraterone Acetate plus Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sedation of Ventilated Traumatic Brain Injury Patients With Midazolam Alone Versus Combination With Dexmedetomidine or Magnesium Sulfate; Monitored by Ultrasonograghic Optic Nerve Sheath Diameter
Status: NOT_YET_RECRUITING
Conditions: TBI (Traumatic Brain Injury)
Interventions: RADIATION: Ultrasonograghic optic nerve sheath diameter US-ONSD|DRUG: midazolam|DRUG: dexmedetomidine|DRUG: magnesium sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Cognitive Behavioral Therapy for Anxiety Disorders in Adolescents With Autism
Status: COMPLETED
Conditions: Autism|Asperger's Syndrome|Pervasive Developmental Disorder Not Otherwise Specified|Generalized Anxiety Disorder|Social Phobia|Separation Anxiety Disorder|Obsessive-compulsive Disorder
Interventions: OTHER: Cognitive Behavioral Therapy|OTHER: Treatment as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comprehensive Postpartum Management for Women With Hypertensive Disorders of Pregnancy
Status: RECRUITING
Conditions: Hypertension, Pregnancy-Induced|Postpartum Preeclampsia|Hypertension; Maternal
Interventions: OTHER: Blood Pressure Control Targets|OTHER: Hypertension Management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study of Trametinib and Ruxolitinib in Colorectal Cancer and Pancreatic Adenocarcinoma
Status: RECRUITING
Conditions: Colorectal Cancer|Pancreatic Adenocarcinoma
Interventions: DRUG: Trametinib|DRUG: Ruxolitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Extracorporeal Shock Wave Therapy After Arthroscopic Rotator Cuff Repair
Status: COMPLETED
Conditions: Rotator Cuff Injuries|Pain, Postoperative|Tissue Adhesion
Interventions: BEHAVIORAL: Radial extracorporeal shockwave therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aspirin in Preventing Colorectal Cancer in Patients With Colorectal Adenoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Colorectal Adenoma
Interventions: DRUG: Aspirin|PROCEDURE: Biospecimen Collection|OTHER: Placebo Administration|OTHER: Questionnaire Administration|PROCEDURE: Rectal Biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Post-Extrasystolic Potentiation as a Predictor of Ventricular Arrhythmias
Status: UNKNOWN
Conditions: Post-extrasystolic Potentiation (PESP)|Ventricular Tachycardia
Interventions: DEVICE: Cardiac stimulation through the device leads
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Destination Therapy Evaluation for Failing Fontan Study
Status: WITHDRAWN
Conditions: Failing Fontan Physiology|Failing Fontan|Single-ventricle|Single-ventricle Fontan|Single-ventricle Physiology
Interventions: DEVICE: HeartMate II Ventricular Assist Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Study to Evaluate the Efficacy and Safety of QLS1128 Orally in Symptomatic Participants With Mild to Moderate COVID-19
Status: RECRUITING
Conditions: COVID-19
Interventions: DRUG: QLS1128|DRUG: QLS1128|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rehabilitation in Muscular Dystrophies From the Hospital Facility to the Home: Pilot Project [RIMUDI]
Status: RECRUITING
Conditions: Muscular Dystrophies|Limb Girdle Muscular Dystrophy|Facio-Scapulo-Humeral Dystrophy|Becker Muscular Dystrophy
Interventions: OTHER: tele-rehabilitation system with virtual reality Home Kit - Virtual Reality Rehabilitation System (VRRS KHYMEIA)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PS-341 Followed by Removal of Prostate for Those With Prostate Cancer
Status: COMPLETED
Conditions: Prostate Neoplasms
Interventions: DRUG: PS-341 (bortezomib)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Using Repetitive Transcranial Magnetic Stimulation (rTMS) in the Rehabilitation of Chronic Spatial Neglect After Stroke
Status: COMPLETED
Conditions: Cerebrovascular Disorders|Cerebral Stroke|VISIO-spatial Neglect|VISUO-spatial Extinction
Interventions: DEVICE: Real rTMS|DEVICE: Sham rTMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of ONCOFID-P-B™ (PACLITAXEL-HYALURONIC ACID)
Status: COMPLETED
Conditions: Bladder Carcinoma in Situ (CIS)
Interventions: DRUG: ONCOFID-P-B™ (PACLITAXEL-HYALURONIC ACID)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT