pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Multiple-Dose Study to Assess the Safety, Tolerability, and Steady State Pharmacokinetics of APD791 in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: APD791
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dose Titration of Propofol for Tracheal Intubation in Children With Sevoflurane Inhalation Induction
Status: COMPLETED
Conditions: Pediatric Urinary Disorders
Interventions: DRUG: propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Cannabidiol for Treatment of Non-affective Psychosis and Cannabis Use
Status: RECRUITING
Conditions: Dual Diagnosis
Interventions: DRUG: Cannabidiol|DRUG: Risperidone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Three Different Assisting Devices to Power Manual Wheelchairs in Patients With Spinal Cord Injury
Status: COMPLETED
Conditions: Spinal Cord Injuries
Interventions: DEVICE: Servomatic™ assisting device|DEVICE: E.Motion© assisting device|DEVICE: Standard manual Wheelchair
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: A Multicenter, Randomized, Double-blind, Placebo-controlled Phase 3 Study to Evaluate the Safety and Efficacy of ES135 in Subjects With Spinal Cord Injury
Status: SUSPENDED
Conditions: Spinal Cord Injuries
Interventions: DRUG: ES135
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Epidermal Langerhans Cell Population in AIDS / ARC Patients by the Topical Application of a Potent Contact Allergen (1-Chloro-2,4-Dinitro-Chlorobenzene) (DNCB)
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Dinitrochlorobenzene
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Comparison of Three Approaches of Electrode Placement to Detect Changes in Motor Evoked Potentials During Spine Surgery
Status: WITHDRAWN
Conditions: Intervertebral Disc Degeneration|Intervertebral Disc Displacement|Spinal Stenosis|Spinal Curvatures|Spondylitis|Spondylosis
Interventions: OTHER: Quadriceps and Rectus Femoris MEP Recording
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: BDNF Level and val66met Polymorphism of Brain Derived Neurotropic Factor Gene in Patients With T2DM and Depression
Status: COMPLETED
Conditions: Depression|Diabetes Mellitus
Interventions: OTHER: Questionare
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Estrogen in Postmenopausal Women With ER Positive Metastatic Breast Cancer After Failure of Sequential Endocrine Therapy
Status: TERMINATED
Conditions: Breast Cancer|Cancer of the Breast|Neoplasms, Breast
Interventions: DRUG: Estrace|DRUG: Anastrozole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment Results for Patients With Central Centrifugal Cicatricial Alopecia (CCCA): a Multicenter Prospective Study
Status: RECRUITING
Conditions: Central Centrifugal Cicatricial Alopecia (CCCA)
Interventions: DRUG: Topical steroid class I-II|DRUG: Triamcinolone Acetonide|DRUG: Doxycyline|DRUG: Minoxidil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phototoxicity Potential of NatrOVA Creme Rinse - 1%
Status: COMPLETED
Conditions: Head Lice
Interventions: DRUG: Spinosad (the active ingredient in NatrOVA)|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Immuncell-LC With Gemcitabine in Resectable Pancreatic Cancer
Status: RECRUITING
Conditions: Pancreatic Ductal Adenocarcinoma
Interventions: DRUG: Immuncell-LC|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Green Tea and Vitamin C on Skin Health
Status: COMPLETED
Conditions: Skin Cancer
Interventions: DIETARY_SUPPLEMENT: Green tea + vitamin C high dose|DIETARY_SUPPLEMENT: Placebo capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Internet-delivered CBT for Adolescents With OCD: A Randomized Controlled Study
Status: COMPLETED
Conditions: Obsessive-Compulsive Disorder
Interventions: BEHAVIORAL: Internet-delivered Cognitive Behavior Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Tolerability of Efgartigimod PH20 SC Given by Prefilled Syringe in Kidney Transplant Recipients With Antibody-Mediated Rejection (AMR)
Status: NOT_YET_RECRUITING
Conditions: Antibody-mediated Rejection
Interventions: COMBINATION_PRODUCT: Efgartigimod PH20 SC - prefilled syringe|OTHER: Placebo PH20 SC - prefilled syringe
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of Two Influenza Vaccines and Placebo in Healthy Adult Subjects
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Cell culture-derived influenza vaccine|BIOLOGICAL: Egg-derived influenza virus vaccine|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Study to Investigate Efficacy & Safety of INT230-6 Compared to US Standard of Care in Adults With Soft Tissue Sarcomas (INVINCIBLE-3)
Status: RECRUITING
Conditions: Sarcoma,Soft Tissue
Interventions: DRUG: INT230-6|DRUG: Eribulin|DRUG: Trabectedin|DRUG: Pazopanib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RESCUE Stroke Caregiver Website to Enhance Discharge Planning
Status: COMPLETED
Conditions: Depression|Quality of Life|Self Efficacy|Recovery of Function|Stress|Positive Aspects of Caregiving
Interventions: BEHAVIORAL: Caregiver problem-solving|OTHER: Standard Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of Safety and Efficacy Comparing ABT-874 Versus Methotrexate in Subjects With Moderate to Severe Plaque Psoriasis
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: ABT-874|DRUG: Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of LY3832479 (LY-CoV016) in Healthy Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: LY3832479|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect of Coffee Consumption on the Serum Levels of Leptin, Folic Acid, and Vitamin B12
Status: UNKNOWN
Conditions: Atherosclerosis
Interventions: BEHAVIORAL: Normal BMI and moderate coffee consumption|BEHAVIORAL: Normal BMI and heavy coffee consumption|BEHAVIORAL: overweight and moderate coffee consumption|BEHAVIORAL: overweight and heavy coffee consumption
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Postpartum Weight Retention
Status: COMPLETED
Conditions: Obesity|Hypertension|Depression
Interventions: BEHAVIORAL: 6 week challenge with 1 year of home visits: health texting, in home exercise supports, social support, healthy eating and feeding classes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: PREvent Viral Exposure and Transmission Study: a COVID-19 (SARS-CoV-2) PEP Study (PREVENT)
Status: WITHDRAWN
Conditions: Respiratory Viral Infection|Respiratory Tract Diseases|COVID-19 Respiratory Infection
Interventions: DRUG: RESP301 (a nitric oxide generating solution)|DRUG: Standard of Care (SOC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of the Management of Vaginal Discharge in West African Using Single Dose Treatments
Status: COMPLETED
Conditions: Bacterial Vaginosis|Candidiasis|Vaginitis
Interventions: DRUG: tinidazole+fluconazole vs metronidazole+clotrimazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Tirzepatide (LY3298176) in Japanese Participants With Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Tirzepatide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of Exoskeleton for Upper Limb Rehabilitation in Neurological Patients
Status: COMPLETED
Conditions: Stroke|Neurologic Disorder
Interventions: DEVICE: AGREE exoskeleton|DEVICE: FEXO exoskeleton|OTHER: Conventional therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Value of Mifepristone in Cervical Preparation Prior to Dilation and Evacuation 19-24 Weeks
Status: COMPLETED
Conditions: Abortion, Induced
Interventions: DRUG: Mifepristone|OTHER: Hygroscopic cervical dilators|DRUG: Misoprostol|DRUG: Intra-amniotic digoxin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Systematic Assessment of Functional Ability, Development of Rehabilitation Plan and Follow-up at Home for Elderly Medical Patients
Status: TERMINATED
Conditions: Geriatric Disorder
Interventions: OTHER: Assessment of functional ability in combination with follow-up at home
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Vaporized Cannabis for Chronic Pain Associated With Sickle Cell Disease
Status: COMPLETED
Conditions: Sickle Cell Disease
Interventions: DRUG: Cannabis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Prevention of Myocardial Enlargement and Dilatation Post Myocardial Infarction Study
Status: COMPLETED
Conditions: Post Myocardial Infarction
Interventions: DEVICE: Cardiac pacing using any Guidant/Boston Scientific Implantable ICD or CRT-D System and any Guidant/Boston Scientific Intracardiac Lead System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Voriconazole and Amphotericin B in Treating Patients With Aspergillosis
Status: COMPLETED
Conditions: Infection|Pulmonary Complications
Interventions: DRUG: amphotericin B deoxycholate|DRUG: voriconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Watch and Wait Versus Surgical Treatment for Clinical Complete Responders After Non-Curative Therapy for Hepatocellular Carcinoma
Status: RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: PROCEDURE: Liver Resection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improving Treatments for Bulimia Nervosa: Innovation in Psychological Interventions for Regulating Eating
Status: UNKNOWN
Conditions: Bulimia Nervosa|Bulimia|Binge Eating|Purging (Eating Disorders)|Eating Disorder
Interventions: BEHAVIORAL: Nutritional Counseling & Acceptance-based Therapy|BEHAVIORAL: Cognitive Behavioral Therapy for Eating Disorders
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Reactogenicity of MPL Adjuvanted Recombinant Hepatitis B- Vaccine and Engerix™-B in Adult Non-Responders
Status: COMPLETED
Conditions: Hepatitis B
Interventions: BIOLOGICAL: Recombinant MPL- adjuvanted hepatitis B vaccine|BIOLOGICAL: Engerix™-B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Study of A-101 Topical Solution for the Treatment of Common Warts
Status: COMPLETED
Conditions: Common Wart
Interventions: DRUG: Active|OTHER: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Music Intervention and Transcranial Electrical Stimulation for Neurological Diseases
Status: RECRUITING
Conditions: Disorder of Consciousness|Stroke
Interventions: OTHER: Combinatory effect of music stimulation and neurostimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Skin Toxicity in Patients With Metastatic Colorectal Cancer Treated With Anti-EGFR and Chemotherapy (DERMIA)
Status: COMPLETED
Conditions: Skin Toxicity
Interventions: DRUG: Doxycycline 50Mg Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hyivy Device as Non-hormonal Therapy in Endometriosis
Status: NOT_YET_RECRUITING
Conditions: Endometriosis|Pelvic Pain
Interventions: DEVICE: Hyivy Intravaginal Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Fruquintinib in Combination With Sintilimab in Advanced Renal Cell Carcinoma (FRUSICA-2)
Status: RECRUITING
Conditions: Advanced Renal Cell Carcinoma
Interventions: DRUG: fruquintinib+sintilimab|DRUG: axitinib / everolimus|DRUG: fruquintinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigation of the Effects of Kinesio Taping and Manual Therapy in Patients With Bruxism
Status: COMPLETED
Conditions: Bruxism
Interventions: PROCEDURE: Manual Therapy|PROCEDURE: Kinesio Taping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I/II Clinical Trial With Interferon Alfa 5 in Treatment-Experienced Patients With Genotype-1 Chronic Hepatitis C
Status: COMPLETED
Conditions: Chronic Hepatitis C Virus Infection|Genotype 1|Treatment-Experienced Patients|Relapses
Interventions: DRUG: Interferon α-5|DRUG: Interferon-α5 plus Interferon-α 2b|DRUG: Interferon α-2b (INTRON® A)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Axillary Node Dissection Versus no Dissection in Breast Cancer With Positive Sentinel Lymph Node
Status: ACTIVE_NOT_RECRUITING
Conditions: Invasive Breast Cancer
Interventions: PROCEDURE: Surgery for standard axillary node dissection|OTHER: No axillary lymph node dissection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Response Rate to Therapy With Docetaxel and Cisplatin in Unresectable Locally Advanced Squamous Cell Carcinoma of Head and Neck
Status: COMPLETED
Conditions: Squamous Cell Carcinoma of Head and Neck
Interventions: DRUG: Cisplatin|DRUG: DOCETAXEL XRP6976|DRUG: Dexamethasone|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Laryngeal Injuries After Anesthesia Induction With Sevoflurane and After Anesthesia Induction With Rocuronium
Status: COMPLETED
Conditions: Laryngeal Injuries
Interventions: DRUG: Sevoflurane|DRUG: Rocuronium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Ezetimibe/Simvastatin Combination in Proteinuric Nephropathy
Status: UNKNOWN
Conditions: Hypercholesterolemia|Chronic Nephropathy
Interventions: DRUG: simvastatin|DRUG: EZE/simvastatin|DRUG: EZE/simvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Extension to a Pivotal Study of Sensory Stimulation in Alzheimer's Disease (OLE Hope Study, CA-0015)
Status: ENROLLING_BY_INVITATION
Conditions: Alzheimer Disease|Cognitive Impairment|Mild Cognitive Impairment|Dementia, Mild|Dementia Moderate|Dementia Alzheimers|Dementia of Alzheimer Type|AD
Interventions: DEVICE: Sensory Stimulation System (GS120) - Active
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Changes in Cytokine Levels After Dextrose Injection in Stage IV Knee Osteoarthritis
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: DRUG: Dextrose 0|DRUG: Aspiration 0|DRUG: Dextrose 1|DRUG: Aspiration 1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Intubation Conditions After RSI Using Rocuronium With Ephedrine Pretreatment
Status: RECRUITING
Conditions: Rapid Sequence Induction and Intubation
Interventions: DRUG: Ephedrine|DRUG: Rocuronium 0.6|DRUG: Rocuronium 0.8|DRUG: Rocuronium 1.2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Testing the Effectiveness of Two Hospitalization Alternatives Compared to Psychiatric Hospitalization (HOSP-ALT)
Status: UNKNOWN
Conditions: Questionnaires|Data Collection
Interventions: DIAGNOSTIC_TEST: Outcome Questionnaire-45|DIAGNOSTIC_TEST: Hopkins symptoms checklist - short form|DIAGNOSTIC_TEST: Prodromal Questionnaire - Brief Version|DIAGNOSTIC_TEST: Manchester Short Assessment of Quality|DIAGNOSTIC_TEST: Self-Stigma of Mental Illness Scale|DIAGNOSTIC_TEST: Session Alliance Inventory - for patient|OTHER: Quality of service/satisfaction questionnaire|DIAGNOSTIC_TEST: Clinical decision-making style|DIAGNOSTIC_TEST: Global Assessment of Functioning Scale|DIAGNOSTIC_TEST: Session Alliance Inventory - for therapist
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pediatric Acute Kidney Injury (AKI) Retrospective, Real-Time and Repository Research
Status: COMPLETED
Conditions: Acute Kidney Injury|Renal Injury|Kidney Disease
Interventions: OTHER: AKI Risk Notification
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SCREENING
Clinical trial: Non-invasive TRanscutaneous Cervical Vagus Nerve Stimulation as a Treatment for Acute Stroke; Safety and Feasibility Study
Status: COMPLETED
Conditions: Stroke, Acute|Stroke, Ischemic|Stroke|Stroke, Hemorrhagic
Interventions: DEVICE: Gammacore device|DEVICE: Gammacore sham device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: CLAG-M or FLAG-Ida Chemotherapy and Reduced-Intensity Conditioning Donor Stem Cell Transplant for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia, Myelodysplastic Syndrome, or Chronic Myelomonocytic Leukemia
Status: RECRUITING
Conditions: Recurrent Acute Myeloid Leukemia|Recurrent Chronic Myelomonocytic Leukemia|Recurrent Myelodysplastic Syndrome|Refractory Acute Myeloid Leukemia|Refractory Chronic Myelomonocytic Leukemia|Refractory Mixed Phenotype Acute Leukemia|Refractory Myelodysplastic Syndrome|Refractory Acute Leukemia of Ambiguous Lineage|Refractory Acute Undifferentiated Leukemia
Interventions: DRUG: Cladribine|DRUG: Cyclophosphamide|DRUG: Cyclosporine|DRUG: Cytarabine|BIOLOGICAL: Filgrastim|PROCEDURE: Hematopoietic Cell Transplantation|DRUG: Mitoxantrone|DRUG: Mycophenolate Mofetil|DRUG: Mycophenolate Sodium|RADIATION: Total-Body Irradiation|DRUG: Idarubicin|DRUG: Fludarabine|DRUG: Cytarabine|PROCEDURE: Multigated Acquisition Scan|PROCEDURE: Echocardiography|PROCEDURE: X-Ray Imaging|PROCEDURE: Bone Marrow Biopsy|PROCEDURE: Bone Marrow Aspiration
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Autologous Tooth Root in Ridge Preservation
Status: RECRUITING
Conditions: Alveolar Ridge Preservation
Interventions: PROCEDURE: Autologous Tooth Root|DRUG: Vit.D3|OTHER: bone graft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Directed Topical Drug Delivery for Treatment for PASC Hyposmia
Status: RECRUITING
Conditions: Post Acute Sequelae Covid-19 Hyposmia
Interventions: DRUG: Beclomethasone|OTHER: Placebo|DEVICE: Microsponge
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hypoxia-guided Radiotherapy With Cisplatin-etoposide in Stage I-III : Small Cell Lung Cancer(SCLC)
Status: WITHDRAWN
Conditions: Small Cell Lung Cancer (SCLC)
Interventions: DRUG: [18F]HX4
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of A High Concentration Liquid Formulation Versus A Lyophilized Formulation of Gantenerumab in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: gantenerumab|DRUG: gantenerumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: HAIC of FOLFOX vs. HAIC of OXA for Advanced HCC
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Sorafenib|DRUG: HAIC of FOLFOX|DRUG: HAIC of OXA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Nutritional Status in ICU : Interest for the Measurement of Body Composition by Body Bioelectrical Impedance and Comparison With Several Methods
Status: COMPLETED
Conditions: Body Composition
Interventions: DEVICE: body bioelectrical impedance
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Short-course Rifamycin-based Regimens for Latent Tuberculosis in Patients With End-stage Kidney Disease
Status: NOT_YET_RECRUITING
Conditions: Latent Tuberculosis|Kidney Failure
Interventions: DRUG: Rifampicin plus Isoniazid|DRUG: Rifapentine plus Isoniazid|DRUG: Rifampicin alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Performance Evaluation of Contact Lenses Among a Population of Adapted Contact Lens Wearers
Status: COMPLETED
Conditions: Vision Disorders
Interventions: DEVICE: PureVision Multi-Focal contact lenses|DEVICE: SofLens59 contact lens
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Open Label Study to Assess the Effect of Secukinumab in Moderate to Severe Papulopustular Rosacea
Status: COMPLETED
Conditions: Papulopustular Rosacea
Interventions: DRUG: Secukinumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open-label Phase 3 Study With Mirabegron in Children From 3 to Less Than 18 Years of Age With Neurogenic Detrusor Overactivity
Status: COMPLETED
Conditions: Neurogenic Detrusor Overactivity
Interventions: DRUG: Mirabegron
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Ofatumumab Compared to Teriflunomide in Patients With Relapsing Multiple Sclerosis.
Status: COMPLETED
Conditions: Relapsing Multiple Scelrosis
Interventions: DRUG: Ofatumumab subcutaneous injection|DRUG: Teriflunomide-matching placebo capsules|DRUG: Teriflunomide capsule|DRUG: Matching placebo of ofatumumab subcutaneous injections
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Feasibility Study of Mesenchymal Trophic Factor (MTF) for Treatment of Osteoarthritis
Status: WITHDRAWN
Conditions: Osteoarthritis of the Knee
Interventions: BIOLOGICAL: Trophic factors from umbilical cord mesenchymal stem cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Therapeutic Evaluative Conditioning to Reduce Adolescents' Self-injurious Thoughts and Behaviors During and After Psychiatric Inpatient Hospitalization
Status: RECRUITING
Conditions: Self-Injurious Behavior|Suicidal Ideation|Suicide Attempts
Interventions: BEHAVIORAL: Therapeutic Evaluative Conditioning|BEHAVIORAL: Neutral comparison condition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of Empagliflozin on Urinary Excretion of Adenosine and Osteocyte Function in Patients With Chronic Kidney Disease
Status: UNKNOWN
Conditions: Chronic Kidney Disease stage3
Interventions: DRUG: Empagliflozin 10 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Phase I Trial of Gemcitabine and Radiation in Locally Advanced Unresectable Cancer of the Pancreas
Status: COMPLETED
Conditions: Gastrointestinal Neoplasms|Pancreatic Neoplasms
Interventions: DRUG: gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Efficacy Of Bacterial Lysate In Asthmatic Children
Status: COMPLETED
Conditions: Allergic Asthma
Interventions: BIOLOGICAL: ISMIGEN|BIOLOGICAL: PLACEBO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Simulation-Based Breast Health Education on Breast Cancer Awareness and Breast Self-Examination Practices
Status: RECRUITING
Conditions: Breast Cancer|Health Knowledge, Attitudes, Practice
Interventions: BEHAVIORAL: simulation-based breast health education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Clinical Research for Azacitidine Combined With Low-dose Dasatinib in Maintenance Therapy of Acute Myeloid Leukemia
Status: UNKNOWN
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Azacitidine|DRUG: Dasatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study Protocol of Venetoclax Combined With Azacitidine and Harringtonine in the Treatment of sAML
Status: RECRUITING
Conditions: Secondary Acute Myeloid Leukemia
Interventions: DRUG: Venetoclax；Azacitidine；Homoharringtonine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RCT of Caloric Restriction vs. Alternate-Day Fasting in Non-Alcoholic Fatty Liver Disease
Status: TERMINATED
Conditions: NAFLD|Obesity|Diabetes Mellitus, Type 2
Interventions: OTHER: Alternate Daily Fasting (ADF)|OTHER: Caloric Restriction (CR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral Care With Propolis in Pediatric Oncology Patients
Status: COMPLETED
Conditions: Oral Mucositis
Interventions: BIOLOGICAL: propolis|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Ketogenic Diet (KD) in Alcoholism
Status: COMPLETED
Conditions: Alcoholism
Interventions: OTHER: Ketogenic Diet (KD)|OTHER: Standard American (SA) Meals and Shakes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Behavioral and Educational Tools to Improve Epilepsy Care
Status: COMPLETED
Conditions: Epilepsy
Interventions: OTHER: Usual Care|BEHAVIORAL: Management of Risks in Epilepsy (MORE)|BEHAVIORAL: Telephone-based motivational interviewing (MORE+MI)|OTHER: Educational Materials
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of PBFT02 in Patients With Frontotemporal Dementia and Progranulin Mutations (FTD-GRN)
Status: RECRUITING
Conditions: Frontotemporal Dementia|FTD|FTD-GRN|Dementia Frontotemporal
Interventions: DRUG: PBFT02
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility of an ED Initiated Online Asthma Management Program for Urban Teens
Status: COMPLETED
Conditions: Acute Asthma
Interventions: BEHAVIORAL: Tailored asthma management program|BEHAVIORAL: Generic web-based education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose:
Clinical trial: PMCAN for Smokers at Smoking Hotspots
Status: COMPLETED
Conditions: Smoking Cessation
Interventions: DRUG: Nicotine Replacement Therapy (NRT)|BEHAVIORAL: Minimal Cessation Advice (MCA)|OTHER: Health warning leaflet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Autologous T-cells Transfected With mRNA Encoding HBV-TCR T Cell Therapy in Combination With NUC for Chronic Hepatitis B
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Hepatitis B
Interventions: BIOLOGICAL: TCR-T
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Study of Atorvastatin Safety and Antitumor Effects in Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Leukemia|Lymphoma, Non-Hodgkin
Interventions: DRUG: Atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Enamel Matrix Derivatives on Systemic Inflammation After Periodontal Therapy
Status: COMPLETED
Conditions: Periodontal Diseases
Interventions: PROCEDURE: Root Instrumentation|DEVICE: EMD Application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I/IIa Study to Evaluate the Safety, PK, PD, and Preliminary Efficacy of PLX8394 in Patients With Advanced Cancers.
Status: TERMINATED
Conditions: Melanoma|Thyroid Cancer|Colorectal Cancer|Non-small Cell Lung Cancer|Cholangiocarcinoma|Histiocytosis|Hairy Cell Leukemia
Interventions: DRUG: PLX8394
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gastric Functions & Proton Pump Inhibitor( PPI) Study
Status: COMPLETED
Conditions: Functional Dyspepsia
Interventions: DRUG: Esomeprazole|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ofatumumab Cardiac Repolarization (QTc) Study in Fludarabine-Refractory Chronic Lymphocytic Leukemia Subjects
Status: COMPLETED
Conditions: Leukaemia, Lymphocytic, Chronic
Interventions: BIOLOGICAL: Ofatumumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study of Combination of Temsirolimus (Torisel®) and Pegylated Liposomal Doxorubicin (PLD, Doxil®/Caelyx®) in Advanced or Recurrent Breast, Endometrial and Ovarian Cancer
Status: UNKNOWN
Conditions: Advanced/Recurrent Breast Cancer|Endometrial Cancer|Ovarian Cancer
Interventions: DRUG: Temsirolimus/PLD
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ketogenic Diet in Infants With Epilepsy (KIWE)
Status: UNKNOWN
Conditions: Epilepsy
Interventions: OTHER: Ketogenic diet|DRUG: Antiepileptic drug therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PK Evaluation of a Nanoformed Oral IR Piroxicam Tablet in Healthy Subjects
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Nanoformed Piroxicam IR Tablet|DRUG: Felden (piroxicam) Tablets|DRUG: Brexidol (piroxicam) Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating a Microfinance Intervention for High Risk Women in Mongolia
Status: COMPLETED
Conditions: HIV Infection
Interventions: BEHAVIORAL: HIV Sexual Risk reduction|BEHAVIORAL: HIV Sexual Risk reduction plus Microfinance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Study of the Effectiveness of Tissue Equivalent on the Basis of Cultured Cells to Heal Skin Blemishes
Status: UNKNOWN
Conditions: Neurotrophic Ulcers|Burns
Interventions: BIOLOGICAL: study of the efficacy of skin equivalent comprising living cells and skin biodegradable substrate for the treatment of skin lesions
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study of Mesdopetam in Patients With Parkinson's Disease Experiencing Levodopa Induced Dyskinesia
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: DRUG: Mesdopetam|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combining Prebiotic and Diet/Physical Activity Educational Program Effects on Body Composition and Intestinal Microbiota in Children
Status: COMPLETED
Conditions: Obesity, Childhood
Interventions: DIETARY_SUPPLEMENT: Beneo Synergy 1|BEHAVIORAL: Project FUN
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Palliative UNConventional Hypofractionation Trial for Metastatic Bone Disease
Status: RECRUITING
Conditions: Metastatic Bone Tumor
Interventions: RADIATION: Experimental Radiation Dose|RADIATION: Conventional Radiation Dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Trial Investigating the Effect of Semaglutide on Hypoglycaemic Counterregulation Compared to Placebo in Subjects With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: semaglutide|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Single Versus Dual Spine Attending Surgeons in Complex Adult Deformity Surgery:
Status: UNKNOWN
Conditions: Scoliosis, Unspecified
Interventions: PROCEDURE: Dual attending|PROCEDURE: Single Attending
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Coronary Artery Ectasia, Efficacy of Various Anti Thrombotic Regimens.
Status: NOT_YET_RECRUITING
Conditions: Coronary Artery Ectasia
Interventions: DRUG: Rivaroxaban 2.5 Mg Oral Tablet twice daily|DRUG: Clopidogrel 75 Mg Oral Tablet|DRUG: Aspirin tablet 75 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Perioperative Chemotherapy With Herceptin For Potentially Resectable HER-2 Positive Gastric Cancer With Liver Metastasis
Status: UNKNOWN
Conditions: HER-2 Positive Gastric Cancer|Liver Metastasis
Interventions: DRUG: Oxaliplatin plus Capecitabine|DRUG: Herceptin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of CKD-501 Versus Pioglitazone When Added to Metformin
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: CKD-501 0.5mg|DRUG: Pioglitazone 15mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ketamine for Reduction of Alcoholic Relapse
Status: COMPLETED
Conditions: Primary Alcohol Use Disorder
Interventions: DRUG: Ketamine|DRUG: Placebo|BEHAVIORAL: Psychological Therapy|BEHAVIORAL: Alcohol Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing High Dose Omeprazole Infusion Against Scheduled Second Endoscopy for Bleeding Peptic Ulcer
Status: COMPLETED
Conditions: Peptic Ulcer Hemorrhage
Interventions: DRUG: Intravenous omeprazole infusion|PROCEDURE: Scheduled second endoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Telecare in Type 1 Diabetes (T1D) Patients Treated by Insulin Pump
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus
Interventions: OTHER: Telecare|OTHER: Conventional therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Induction Chemotherapy Followed by Chemoradiotherapy in Esophageal Cancer
Status: COMPLETED
Conditions: Neoplasms
Interventions: DRUG: Docetaxel|DRUG: Cisplatin|RADIATION: Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Role of Alcohol Consumption in the Aetiology of Different Cardiovascular Disease Phenotypes: a CALIBER Study
Status: UNKNOWN
Conditions: Chronic Stable Angina|Unstable Angina|Coronary Heart Disease Not Otherwise Specified|Acute Myocardial Infarction|Heart Failure|Ventricular Arrhythmias|Cardiac Arrest|Abdominal Aortic Aneurysm|Peripheral Arterial Disease|Ischaemic Stroke|Subarachnoid Haemorrhagic Stroke|Intracerebral Haemorrhagic Stroke|Stroke Not Otherwise Specified|Sudden Cardiac Death|Unheralded Coronary Death|Mortality|Coronary Heart Disease (CHD)|Cardiovascular Disease (CVD)|Fatal Cardiovascular Disease (Fatal CVD)|ST Elevation Myocardial Infarction (STEMI)|Non-ST Elevation Myocardial Infarction (nSTEMI)|Myocardial Infarction Not Otherwise Specified (MI NOS)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Observational Study to Evaluate the Quality of Life of Healthy Postmenopausal Women Who Take Coenzyme Q-Ubiquinol
Status: COMPLETED
Conditions: Health Status
Interventions: DIETARY_SUPPLEMENT: Coenzima Q - QubiquinolCoenzyme Q - Qubiquinol
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phase I/II Study of AZD2171 in Combination With Paclitaxel/Carboplatin in Japanese Non-Small Cell Lung Cancer Patients
Status: TERMINATED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: AZD2171|DRUG: Paclitaxel|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vitamin D and Pre Cachexia and Cancer Cachexia in Epithelial Ovarian Cancer
Status: UNKNOWN
Conditions: Epithelial Ovarian Cancer
Interventions: DIETARY_SUPPLEMENT: Vitamin D|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Low Glycemic Index Diet in Children With Drug-resistant Epilepsy
Status: COMPLETED
Conditions: Ketogenic Diet|Drug Resistant Epilepsy|Oxidative Stress|Quality of Life|Psychological Health
Interventions: OTHER: Low glycemic index diet treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Short-term Effect of Glucose and Sacharose Ingestion on Cognitive Performance and Mood in Elderly
Status: COMPLETED
Conditions: Mental Health|Cognition|Memory|Attention
Interventions: DIETARY_SUPPLEMENT: glucose|DIETARY_SUPPLEMENT: sacharose|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Effect of Aprotinin on Transfusion Requirements and Blood Loss in Patients Undergoing Elective Primary Total Hip Replacement
Status: COMPLETED
Conditions: Blood Loss, Surgical
Interventions: DRUG: Trasylol (Aprotinin, BAYA0128)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Rituximab for Obsessive-compulsive Disorder. (RITS-PO-2019)
Status: COMPLETED
Conditions: Obsessive-Compulsive Disorder|Treatment Resistant Disorders
Interventions: DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity Study of Influenza Vaccines in HIV-infected and HIV-uninfected Pregnant Women in Western Kenya
Status: WITHDRAWN
Conditions: Influenza, Human|HIV|Malaria|Tetanus|Polio
Interventions: BIOLOGICAL: Quadrivalent Inactivated Influenza Vaccine (QIV)|BIOLOGICAL: Inactivated Polio Vaccine|BIOLOGICAL: Double Dose QIV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: COVID-19 Treatment in South Africa
Status: COMPLETED
Conditions: COVID-19
Interventions: OTHER: Standard of care (Paracetamol)|DRUG: Artesunate-amodiaquine|DRUG: Pyronaridine-artesunate|DRUG: Favipiravir plus Nitazoxanide|DRUG: Sofosbuvir/daclatasvir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Titanium Mesh Coated With Natural Hydroxyapatite Nanocrystals in Orbital Reconstruction
Status: UNKNOWN
Conditions: Orbital Deformity
Interventions: OTHER: Coated titanium mesh|OTHER: Uncoated titanium mesh
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prevention of Progression of Prediabetes, Obesity and CV Risk
Status: RECRUITING
Conditions: Pre-Diabetes|Weight, Body|Cardiovascular Diseases
Interventions: DRUG: Placebo|DRUG: Rybelsus Tablet|DRUG: Jardiance 25Mg Tablet|DRUG: Metformin|DRUG: Actos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Trial Investigating the Efficacy and Safety of Insulin Degludec/Insulin Aspart Once Daily Plus Insulin Aspart for the Remaining Meals Versus Insulin Detemir Once or Twice Daily Plus Meal Time Insulin Aspart in Children and Adolescents With Type 1 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 1
Interventions: DRUG: insulin degludec/insulin aspart|DRUG: insulin aspart|DRUG: insulin detemir|DRUG: insulin aspart
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Safety and Effectiveness of Peridex in Preventing or Delaying Fungal Infections of the Mouth in HIV-Infected Patients
Status: COMPLETED
Conditions: Candidiasis, Oral|HIV Infections
Interventions: DRUG: Chlorhexidine gluconate
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: 18F-FET-PET/MRI vs Standard MRI Alone for Stereotactic RadioTherapy Planning for High Grade Brain Gliomas
Status: ACTIVE_NOT_RECRUITING
Conditions: Glioma, Malignant
Interventions: DIAGNOSTIC_TEST: 0-(2-18F-Fluoroethyl)-L-Tyrosine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC