pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Effects of Intranasal Insulin on Neuroimaging Markers and Cognition in Patients With Psychotic Disorders
Status: RECRUITING
Conditions: Psychosis|Schizophrenia|Schizo Affective Disorder|Bipolar I Disorder
Interventions: DRUG: Intranasal Insulin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Ibuprofen Inhibits Human Sweet Taste
Status: COMPLETED
Conditions: Treatment of Sweet Taste Receptors Without or With an Oral Rinse of Ibuprofen Solution in Healthy Participants|Treatment of Sweet Taste Receptors Without or With an Oral Rinse of Naproxen Solution in Healthy Participants
Interventions: DRUG: Inhibition of Sweet Taste by Ibuprofen Oral Rinses|DRUG: Inhibition of Sweet Taste by Naproxen Oral Rinses
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Analysis of the Diagnostic Performance of LacryDiag, a New Analyzer of the Ocular Surface in the Dry Eye
Status: COMPLETED
Conditions: Dry Eye
Interventions: DIAGNOSTIC_TEST: Time #1: Non Invasive Break-Up Time (NIBUT)|DIAGNOSTIC_TEST: Time #2: MicroInstillation Break-Up Time (MIBUT) + Oxford score|DIAGNOSTIC_TEST: Time #3: Standard Break-Up Time (SBUT)|DIAGNOSTIC_TEST: Time #4: Schirmer test|DIAGNOSTIC_TEST: Satisfaction questionnaire to the patient
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Early Use of Airway Pressure Release Ventilation (APRV) in ARDS
Status: RECRUITING
Conditions: Acute Respiratory Distress Syndrome
Interventions: DEVICE: APRV. General Electric Healthcare Engstrom ventilator system|DEVICE: Conventional. General Electric Healthcare Engstrom ventilator system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CT0594CP CAR-T Cells in Patients With Relapsed/Refractory Multiple Myeloma or Plasma Cell Leukemia
Status: RECRUITING
Conditions: Multiple Myeloma|Plasma Cell Leukemia
Interventions: BIOLOGICAL: CT0594CP
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Targeted Lower Extremity Joint Training on Multiple Sclerosis (MS) Gait Abnormalities
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DEVICE: Ankle-bot|OTHER: Conventional focused ankle therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Assessment of Immune Response in Newly Diagnosed Glioblastoma Patients Treated With Pembrolizumab
Status: RECRUITING
Conditions: Newly Diagnosed Glioblastoma
Interventions: DRUG: Pembrolizumab|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exercise Induced Bronchoconstriction (0476-359)
Status: COMPLETED
Conditions: Asthma, Exercise-induced
Interventions: DRUG: montelukast sodium|DRUG: Comparator: placebo (unspecified)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of the Safety and Contraceptive Efficacy of Relugolix Combination Therapy in Women With Uterine Fibroids or Endometriosis Who Are at Risk for Pregnancy
Status: ACTIVE_NOT_RECRUITING
Conditions: Contraception
Interventions: DRUG: Relugolix Combination Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Eltrombopag in Pediatric Patients With Thrombocytopenia From Chronic Idiopathic Thrombocytopenic Purpura (ITP)
Status: COMPLETED
Conditions: Purpura, Thrombocytopaenic, Idiopathic
Interventions: DRUG: eltrombopag|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Endocrine Therapy in Breast Cancer
Status: COMPLETED
Conditions: Highly Endocrine Responsive Operable Breast Cancer
Interventions: DRUG: Letrozole 2.5Mg Tablet|DRUG: GnRH analogue
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Efficacy and Safety of Oral CT1812 in Participants With Geographic Atrophy (GA) Secondary to Dry Age-Related Macular Degeneration (AMD).
Status: RECRUITING
Conditions: Age-Related Macular Degeneration
Interventions: DRUG: Active Comparator CT1812|DRUG: Placebo Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Felodipine Controlled Release Tablets and Felodipine Sustained Release Tablets in Healthy Subjects Under Fasting State Comparative Pharmacokinetic Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Hypertension
Interventions: DRUG: Felodipine sustained release tablets (trade name: plendil®)|DRUG: Felodipine Controlled Release Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Tandem High Dose Chemotherapy and Autologous Stem Cell Rescue for High Risk Pediatric Brain Tumors
Status: UNKNOWN
Conditions: Brain Tumors
Interventions: DRUG: HDCT 1(TTC), HDCT2(MEC)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Olanzapine Orally Disintegrating Tablets, 5 mg Under Fasting Condition
Status: COMPLETED
Conditions: Fasting
Interventions: DRUG: Olanzapine OD Tablets 5 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BIIB057 in Subjects With Rheumatoid Arthritis and Inadequate Response to Disease-Modifying Antirheumatic Drugs
Status: WITHDRAWN
Conditions: Rheumatoid Arthritis
Interventions: DRUG: BIIB057|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of RAD 001 as Second Line Therapy in Patients With Transitional Cell Carcinoma TCC of the Urothelium
Status: COMPLETED
Conditions: Urothelial Cancer
Interventions: DRUG: Everolimus (Afinitor®)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Study of a Fixed Dose Combination Nefopam Hydrochloride (30 mg) / Paracetamol (500 mg)
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: nefopam hydrochloride 30mg X2|DRUG: paracetamol 500 mg X2|DRUG: Combination Product: nefopam hydrochloride 30mg / paracetamol 500mg X2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Testosterone Gel in Preventing Weakness Caused by Steroid Therapy in Men With Glioma
Status: TERMINATED
Conditions: Brain and Central Nervous System Tumors|Musculoskeletal Complications
Interventions: DRUG: testosterone gel applied to skin|DIETARY_SUPPLEMENT: whey powder protein
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy and Safety of Four Doses of Cenerimod Compared to Placebo in Adult Subjects With Active Systemic Lupus Erythematosus
Status: COMPLETED
Conditions: Systemic Lupus Erythematosus
Interventions: DRUG: Cenerimod 0.5 mg|DRUG: Cenerimod 1 mg|DRUG: Cenerimod 2 mg|DRUG: Cenerimod 4 mg|DRUG: Placebo|DRUG: cenerimod 2 mg (ex-4 mg)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Utomilumab, Cetuximab, and Irinotecan Hydrochloride in Treating Patients With Metastatic Colorectal Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Colorectal Carcinoma|Stage IV Colorectal Cancer AJCC v8|Stage IVA Colorectal Cancer AJCC v8|Stage IVB Colorectal Cancer AJCC v8|Stage IVC Colorectal Cancer AJCC v8
Interventions: BIOLOGICAL: Cetuximab|DRUG: Irinotecan Hydrochloride|OTHER: Pharmacodynamic Study|BIOLOGICAL: Utomilumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Labetalol to Prevent Hypertension and Tachycardia During Fiberoptic Bronchoscopy
Status: COMPLETED
Conditions: Bronchoscopy
Interventions: DRUG: Labetalol 10mg iv
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Correlation of Radiological Lesions With Vestibular Function in Patients With Bilateral Vestibulopathy
Status: RECRUITING
Conditions: Hearing Loss, Sensorineural|Bilateral Vestibular Deficiency|DFNA9|Radiology
Interventions: DIAGNOSTIC_TEST: vestibular test 1|DIAGNOSTIC_TEST: vestibular test 2|DIAGNOSTIC_TEST: vestibular evoked myogenic potentials|DIAGNOSTIC_TEST: audiometry|DIAGNOSTIC_TEST: CT and MR imaging of temporal bone|GENETIC: p.P51S mutation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A 52 Week Open-label Extension Trial Following the Double-blind Efficacy and Safety Study R076477-SCH-305.
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Paliperidone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exercise Program Among Lung Cancer Dyads
Status: COMPLETED
Conditions: Lung Cancer|Depression|Physical Activity|Quality of Life|Pain|Lung Cancer Symptoms
Interventions: BEHAVIORAL: Exercise Intervention|OTHER: Survey Administration|OTHER: Quality-of-Life Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Deep Brain Stimulation for Patients With Dementia With Lewy Bodies
Status: COMPLETED
Conditions: Dementia With Lewy Bodies
Interventions: PROCEDURE: Bilateral Nucleus Basalis Meynert DBS|PROCEDURE: Sham Nucleus Basalis Meynert DBS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of HR091506 Tablets in Treatment of Gout With Hyperuricemia in Adults
Status: NOT_YET_RECRUITING
Conditions: Gout With Hyperuricemia in Adults
Interventions: DRUG: HR091506 tablets + placebo of febuxostat tablets|DRUG: febuxostat tablets + placebo of HR091506 tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Daily Imaging, Target Identification, and Simulated Computed Tomography-Based Stereotactic Adaptive Radiotherapy Workflow in a Novel Ring Gantry Radiotherapy Device
Status: COMPLETED
Conditions: Cancer of Pancreas|Cancer of Pelvis|Cancer of Abdomen|Cancer of Thorax
Interventions: DEVICE: Ring gantry kV-CBCT combined with linear accelerator
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Study Comparing Treatment With Alluzience vs Reconstituted Toxin
Status: COMPLETED
Conditions: Glabellar Frown Lines
Interventions: BIOLOGICAL: Alluzience|BIOLOGICAL: powder BoNT-A (BOTOX/Vistabel)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Efficacy of Amorphous Calcium Carbonate (ACC) Compared to Placebo and Best Available Care (BAT), for the Treatment of Moderate to Severe COVID-19 Patients.
Status: COMPLETED
Conditions: Covid19
Interventions: DRUG: AMOR 18 Powder & Inhalation|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AMG 282 in Healthy Subjects and Subjects With Chronic Rhinosinusitis With Nasal Polyps
Status: COMPLETED
Conditions: Chronic Rhinosinusitis With Nasal Polyps
Interventions: DRUG: AMG 282|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Association of Adjuvant Radiotherapy of Non-metastatic Breast Carcinoma With Immunomodulation and Circulating Tumor Cell Phenotype in Relation to Patient Age.
Status: RECRUITING
Conditions: Tumor Cell, Circulating
Interventions: RADIATION: Adjuvant radiotherapy|DRUG: neoadjuvant and adjuvant chemotherapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Interactive Mobile Health Intervention to Improve Early Postpartum Modern Contraceptive Method Uptake
Status: RECRUITING
Conditions: Other Cardiovascular Diseases of Mother, Postpartum
Interventions: BEHAVIORAL: Mobile health intervention(mHealth)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: COMPOUND (INN): HOE490O - GLIMEPIRIDE / METFORMIN HCl (Amaryl® M)0 (Glimepiride/Metformin Hydrochloride Immediate Release Combination Tablet) in Fed Conditions in Healthy Male and/or Female Subjects.
Status: WITHDRAWN
Conditions: Healthy
Interventions: DRUG: : Amaryl® M IR 2/1000
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Validation of CPR for Manipulation for Neck Pain
Status: TERMINATED
Conditions: Cervicalgia
Interventions: PROCEDURE: Manipulation|PROCEDURE: Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intramedullary Resorbable Fixation System Versus K-wire for the Treatment of Lesser Toe Deformities
Status: COMPLETED
Conditions: Hammer Toe|Surgery|Deformity of Toe|Phalanx; Dislocation Toe(S)
Interventions: PROCEDURE: Arthrodesis interphalangeal with intramedullary resorbable fixation system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Open-Label Safety and Tolerability Study of INCB057643 in Subjects With Advanced Malignancies
Status: TERMINATED
Conditions: Solid Tumors
Interventions: DRUG: INCB057643|DRUG: Gemcitabine|DRUG: Paclitaxel|DRUG: Rucaparib|DRUG: Abiraterone|DRUG: Ruxolitinib|DRUG: Azacitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dysphagia Evaluation After Stroke- Effect Oral Neuromuscular Training on Swallowing Dysfunction
Status: RECRUITING
Conditions: Dysphagia|Stroke
Interventions: DEVICE: Oral neuromuscular training using an oral device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Open-Label, Long-Term Study of Oral Treprostinil in Subjects With Pulmonary Arterial Hypertension
Status: COMPLETED
Conditions: Pulmonary Arterial Hypertension
Interventions: DRUG: UT-15C (treprostinil diolamine)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and the Pharmacokinetics of Ridinilazole in Adolescent Subjects
Status: TERMINATED
Conditions: Clostridioides Difficile Infection
Interventions: DRUG: Ridinilazole|DRUG: Vancomycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of KT Taping on Waist-to-hip Ratio, Abdominal Strength and Body Image Concerns in Postpartum Females.
Status: COMPLETED
Conditions: Postpartum Disorder
Interventions: OTHER: Kinesio taping with abdominal exercises|OTHER: Abdominal exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Clinical Trial to Investigate the Safety, Tolerability and Efficacy of YH1885L in Patients With Non-erosive Reflux Disease(NERD)
Status: COMPLETED
Conditions: Non-erosive Reflux Disease
Interventions: DRUG: YH1885L(Revaprazan)|DRUG: Esomeprazole 20mg|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety, Tolerability, and Efficacy of IMB-1018972 in Patients With Refractory Angina
Status: SUSPENDED
Conditions: Refractory Angina
Interventions: DRUG: IMB-1018972|DRUG: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trocar Site Hernia After Laparoscopic Cholecystectomy, Supra Versus Infraumbilical Incision for Umbilical Trocar Entry
Status: COMPLETED
Conditions: Incisional Hernia|Cholecystectomy, Laparoscopic
Interventions: PROCEDURE: Infraumbilical Hasson trocar incision|PROCEDURE: Supraumbilical Hasson trocar incision
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effect of a Deworming Intervention to Improve Early Childhood Growth and Development in Resource-poor Areas
Status: COMPLETED
Conditions: Malnutrition|Intestinal Diseases, Parasitic
Interventions: DRUG: Mebendazole|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Exercise Trial and Economic Analysis in Men With Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: BEHAVIORAL: Supervised 1:1 exercise|BEHAVIORAL: Supervised group exercise|BEHAVIORAL: Home-based exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: LEAC-102 for Advanced Colorectal Cancer
Status: UNKNOWN
Conditions: Advanced Colorectal Cancer
Interventions: DRUG: LEAC-102 500mg capsule and FOLFOX + Bevacizumab/Cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Mesenchymal Stem Cell Counts in Unilateral vs. Bilateral Posterior Superior Iliac Spine Bone Marrow Aspiration
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: PROCEDURE: Unilateral Bone Marrow Procurement|PROCEDURE: Bilateral Bone Marrow Procurement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Antibiotic Usage Prior to OnabotulinumtoxinA Injection
Status: RECRUITING
Conditions: Antibiotic Stewardship|Overactive Bladder|Onabotulinumtoxin A|UTI
Interventions: OTHER: No antibiotic|OTHER: Prophylactic antibiotic|PROCEDURE: cystoscopic injection of onabotulinumtoxinA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Calcium, Dairy, and Body Fat in Adolescents
Status: COMPLETED
Conditions: Obesity|Energy Metabolism
Interventions: DIETARY_SUPPLEMENT: C (smoothies based on soy protein containing no additional calcium)|DIETARY_SUPPLEMENT: B (smoothies based on soy protein containing calcium)|DIETARY_SUPPLEMENT: A (smoothies based on dairy protein containing calcium)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of a Mobile-based Multidomain Intervention to Improve Cognitive Function and Health-related Outcomes Among Older Korean Adults With a High Risk of Dementia
Status: COMPLETED
Conditions: Cognitive Decline|Cognitive Impairment, Mild|Aging|Dementia
Interventions: DEVICE: mobile-based|OTHER: paper-based
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of Oseltamivir (Tamiflu) for the Seasonal Prophylaxis of Influenza in Immunocompromised Participants
Status: COMPLETED
Conditions: Influenza
Interventions: DRUG: Oseltamivir|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Sacituzumab Govitecan in Chinese Patients With Metastatic Triple-negative Breast Cancer Who Received at Least Two Prior Treatments
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Triple-negative Breast Cancer
Interventions: DRUG: Sacituzumab Govitecan-hziy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Correlation Between Sleep Quality and Atrial Fibrillation Undergoing High-flow Nasal Cannula Oxygen (HFNC)
Status: UNKNOWN
Conditions: Hypoxemia
Interventions: DEVICE: heated humidified high-flow nasal cannula|DEVICE: noninvasive ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multifactorial Intervention on Cardiovascular Risk Factors in Subjects With Peripheral Arterial Disease
Status: UNKNOWN
Conditions: Peripheral Arterial Disease|Hypercholesterolemia|Hypertension|Diabetes Mellitus|Smoking
Interventions: DRUG: Stepwise therapy for dyslipidemia, hypertension and diabetes|BEHAVIORAL: Dietary recommendations|BEHAVIORAL: Increase in physical activity|BEHAVIORAL: Smoking cessation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: ECT
Clinical trial: High-Dose Combination Chemotherapy and Peripheral Stem Cell Transplantation in Treating Patients With Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: BIOLOGICAL: Filgrastim (G-CSF)|DRUG: Cyclophosphamide|DRUG: Doxorubicin Hydrochloride|DRUG: Paclitaxel|PROCEDURE: Peripheral Blood Stem Cell Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Preliminary Efficacy of Sublingual Liraglutide in Patients With Type 2 Diabetes Mellitus
Status: RECRUITING
Conditions: Diabete Type 2
Interventions: DRUG: Liraglutide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Immunogenicity and Safety of GlaxoSmithKline (GSK)'s Infanrix Hexa Vaccine (DTPa-HBV-IPV/Hib) Versus MCM Vaccine BV's Vaxelis Vaccine (DTaP5-HBV-IPV-Hib) in Healthy Infants and Toddlers
Status: COMPLETED
Conditions: Diphtheria
Interventions: BIOLOGICAL: DTPa-HBV-IPV/Hib|BIOLOGICAL: DTaP5-HBV-IPV-Hib|BIOLOGICAL: Pneumococcal 13-valent conjugate vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Oral Hygiene Procedures on Reduction of Oral Malodor
Status: COMPLETED
Conditions: Halitosis
Interventions: DRUG: group 1: drug: chlorine dioxide|DEVICE: group 2: device: small tooth brush for tongue cleaning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Postprandial Monocyte Study
Status: RECRUITING
Conditions: Immune System|Nutrition|Inflammation
Interventions: OTHER: High saturated fat challenge meal|OTHER: High mono unsaturated fat challenge meal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Single and Multiple Ascending Doses of M5542 Administered in Healthy Volunteers
Status: NOT_YET_RECRUITING
Conditions: Healthy
Interventions: BIOLOGICAL: M5542|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Dose-range-finding, Phase 2 Trial of Oral Linaclotide Acetate Administered to Patients With Chronic Constipation
Status: COMPLETED
Conditions: Chronic Constipation
Interventions: DRUG: linaclotide acetate|DRUG: Matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Zinc on Glucose Homeostasis
Status: RECRUITING
Conditions: Prediabetic State|Hyperglycemia
Interventions: DRUG: Zinc Gluconate 30 MG|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Antigagging Effect of Granisetron (Kytril), an Antiemetic Drug, in Dental Situations
Status: UNKNOWN
Conditions: Antiggaging Effect|Antiemetic|Granisetron|Gag Reflex|Dental Situations
Interventions: DRUG: GRANISETRON
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose:
Clinical trial: Blmf, Lenalidomide and Dexamethasone in Transplant-ineligible Patients With Newly Diagnosed Multiple Myeloma
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: Belantamab mafodotin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Inhalation of Sevoflurane Versus Intravenous Midazolam,Ketamine,Propofol For Pediatrics Undergoing Upper GI Endoscopy
Status: UNKNOWN
Conditions: Upper GI Bleeding
Interventions: DRUG: Sevoflurane Inhalation Solution|DRUG: Midazolam, Ketamine and Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: L-Carnitine Supplementation, Rate of Weight Gain and EED in Children With SAM
Status: COMPLETED
Conditions: Malnutrition
Interventions: DRUG: L- carnitine oral solution|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: The Kinetics of Endocannabinoids in Patients With Chemotherapy Induced Peripheral Neuropathy by Using Medical Cannabis.
Status: UNKNOWN
Conditions: Chemotherapy-induced Peripheral Neuropathy
Interventions: DRUG: medical cannabis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Performance of Posterior Partial Coverage Coronal Restorations Luted With Two Differrent Systems.
Status: RECRUITING
Conditions: Unsatisfactory or Defective Restoration of Tooth
Interventions: DEVICE: IPS Empress Direct|DEVICE: Bisco Duo-Link Universal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Short Term Efficacy and Safety of Perispinal Administration of Etanercept in Mild to Moderate Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: BIOLOGICAL: Etanercept|DIETARY_SUPPLEMENT: Curcum.Luteol.Theaflav.Lip.Acid,FishOil,Quercet.,Resveratr.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Perioperative Nutrition in Gastric Bypass Surgery
Status: COMPLETED
Conditions: Postoperative Complications|Gastric Bypass
Interventions: DIETARY_SUPPLEMENT: Glucose load (Nutricia)|OTHER: Post operative early enteral feeding
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Lenvatinib Plus Pembrolizumab in Merkel Cell Carcinoma
Status: RECRUITING
Conditions: Merkel Cell Carcinoma|Neuroendocrine Carcinoma of the Skin|Trabecular Carcinoma of the Skin
Interventions: DRUG: Lenvatinib Oral Product|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety, Tolerability and Drug Levels of BMS-986447 in Healthy Participants
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DRUG: BMS-986447|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Salivary Neuropilin-1 (NRP-1), Cotinine and C-Reactive Protein (CRP) Levels With Periodontal Clinical Parameters in Smokers and Non-Smokers With Different Periodontal Diseases
Status: RECRUITING
Conditions: Periodontal Diseases
Interventions: DIAGNOSTIC_TEST: Saliva obtaining
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: 18F-FACBC PET/CT and the PSA Kinetics for PCa Patients With Biochemical Recurrence.
Status: UNKNOWN
Conditions: Biochemical Relapse Fo Malignant Neoplasm of Prostate
Interventions: RADIATION: 18F-FACBC PET/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Vessel Sealing System Uvulopalatoplasty Versus Uvulopalatal Flap
Status: UNKNOWN
Conditions: Snoring|Obstructive Sleep Apnea
Interventions: PROCEDURE: Vessel sealing system uvulopalatoplasty (VSSU)|PROCEDURE: Uvulopalatal flap (UPF)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PROTECT TAVI - Prospective Randomized Outcome Study in TAVI Patients Undergoing Periprocedural Embolic Cerebral Protection With the Sentinel™ Device
Status: UNKNOWN
Conditions: Cerebral Embolization During TAVI Using Balloon-expandable vs. Self-expandable Valves
Interventions: DEVICE: TAVI: Edwards SAPIEN 3, Edwards Lifesciences, Edwards Sapien Ultra|DEVICE: TAVI: Edwards SAPIEN 3, Edwards Lifesciences, Edwards Sapien Ultra; Sentinel™ Cerebral Protection Systems|DEVICE: TAVI: CoreValve® Evolut R™, CoreValve Medtronic|DEVICE: TAVI: CoreValve® Evolut R™, CoreValve Medtronic; Sentinel™ Cerebral Protection Systems
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Time Restricted Eating for the Treatment of Type 2 Diabetes
Status: ACTIVE_NOT_RECRUITING
Conditions: Diabetes Mellitus, Type 2|Obesity
Interventions: OTHER: Time restricted feeding (TRF)|OTHER: Daily calorie restriction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Regional-anaesthesiological Infiltration Techniques for the Management of Chronic Pain: a Retrospective Study
Status: COMPLETED
Conditions: Chronic Pain|Trigeminal Neuralgia|Cluster Headache|Post-Zoster Neuralgia|Post Zoster Pain|Neuropathic Pain
Interventions: PROCEDURE: regional-anaesthesiological infiltration
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Drinking at PACU Discharge After General Anaesthesia With Airway Control on Aspiration, Vomiting and Patients Comfort
Status: COMPLETED
Conditions: Scheduled General Anaesthesia With Airway Control
Interventions: PROCEDURE: Early oral fluid recovery.|PROCEDURE: Delayed oral fluid recovery.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Phase II Study of Axitinib (AG-013736) With Evaluation of the VEGF-Pathway in Metastatic, Recurrent or Primary Unresectable Adrenocortical Cancer
Status: COMPLETED
Conditions: Adrenal Cortex Neoplasms
Interventions: DRUG: Axitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dextenza for Post-operative Treatment of Pterygium
Status: UNKNOWN
Conditions: Pterygium of Both Eyes
Interventions: DRUG: Intracanalicular Dexamethasone, (0.4 mg) Insert|DRUG: Prednisolone Acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Magnetic Resonance Imaging for the Early Detection of CNS Metastases in Women With Stage IV Breast Cancer
Status: UNKNOWN
Conditions: Breast Cancer|Metastatic Cancer
Interventions: BIOLOGICAL: trastuzumab|DRUG: chemotherapy|PROCEDURE: magnetic resonance imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: DIAGNOSTIC
Clinical trial: Warming Mattress Versus Polyethylene Wrapping to Prevent Hypothermia in Preterm Newborns.
Status: COMPLETED
Conditions: Hypothermia
Interventions: DEVICE: NeoWrap|DEVICE: InfaTherm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Application of New Oropharyngeal Airway Management in Patients Undergoing Painless Gastroenteroscopy
Status: RECRUITING
Conditions: Airway Management
Interventions: DEVICE: New oropharyngeal airway group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Tinnitus Retraining Therapy Trial
Status: COMPLETED
Conditions: Subjective Tinnitus
Interventions: DEVICE: Conventional sound generator (SG)|DEVICE: Placebo sound generator (placebo SG)|BEHAVIORAL: Standard of Care (SC)|BEHAVIORAL: Directive Counseling (DC)|BEHAVIORAL: Directive Counseling (DC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Role of Type 2 Diabetes in Potentiating the Inflammatory Response Post Extracorporeal Circulation After Cardiac Surgery
Status: WITHDRAWN
Conditions: Inflammatory Response|Extracorporeal Circulation; Complications|Cardiac Surgery|Type 2 Diabetes
Interventions: PROCEDURE: The role of the activation of the NLRP3 inflammasome after cardiac surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Vaccine Therapy With or Without Sargramostim in Treating Patients With High-Risk or Metastatic Melanoma
Status: UNKNOWN
Conditions: Melanoma (Skin)
Interventions: BIOLOGICAL: MAGE-10.A2|BIOLOGICAL: MART-1 antigen|BIOLOGICAL: NY-ESO-1 peptide vaccine|BIOLOGICAL: sargramostim|BIOLOGICAL: tyrosinase peptide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Obstructive Sleep Apnea, CPAP Treatment & Cognitive Ability in HIV
Status: UNKNOWN
Conditions: Hiv|Obstructive Sleep Apnea|Cognitive Change
Interventions: BEHAVIORAL: CPAP intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Standardised Drug Provocation Testing in Perioperative Hypersensitivity
Status: RECRUITING
Conditions: Allergic Reaction|Hypersensitivity|Perioperative Complication|Anaphylaxis|Anaphylactic Reaction|Immediate Hypersensitivity|Hypersensitivity, Drug
Interventions: DIAGNOSTIC_TEST: Full dose DPT with propofol|DIAGNOSTIC_TEST: Full dose DPT with ketamine|DIAGNOSTIC_TEST: Full dose DPT with etomidate|DIAGNOSTIC_TEST: Full dose DPT with midazolam|DIAGNOSTIC_TEST: Full dose DPT with fentanyl|DIAGNOSTIC_TEST: Full dose DPT with sufentanyl|DIAGNOSTIC_TEST: Full dose DPT with alfentanil|DIAGNOSTIC_TEST: Full dose DPT with remifentanil|DIAGNOSTIC_TEST: Full dose DPT with rocuronium|DIAGNOSTIC_TEST: Full dose DPT with atracurium|DIAGNOSTIC_TEST: Full dose DPT with cisatracurium|DIAGNOSTIC_TEST: Full dose DPT with succinylcholine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study to Evaluate the Immune Response and the Safety of Fluarix TM/ Influsplit SSW® 2010/2011 or Pandemrix TM
Status: TERMINATED
Conditions: Influenza
Interventions: BIOLOGICAL: PandemrixTM|BIOLOGICAL: FluarixTM/ Influsplit SSW® 2010/2011
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effectiveness of Core Stabilization Exercises With and Without Neural Mobilization Technique in Female Patients With Lumbar Radiculopathy Due to Disc Herniation - an RCT Study
Status: RECRUITING
Conditions: Lumbar Disc Herniation
Interventions: OTHER: Core stabilization exercises|OTHER: Core stabilization exercises + neural mobilization technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess Drug Concentrations in Plasma of Different Extended-release Formulations of AZD1305
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: AZD1305|DRUG: AZD1305|DRUG: AZD1305
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of Tiotropium in the HandiHaler Versus the Respimat in Chronic Obstructive Pulmonary Disease
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: tiotropium 18 mcg|DRUG: tiotropium 1.25 mcg (2 actuations/day)|DRUG: tiotropium 2.5 mcg (2 actuations/day)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Lidocaine Patch in Acute Musculoskeletal Pain in the Emergency Department
Status: COMPLETED
Conditions: Acute Musculoskeletal Disease|Sprains|Sprains and Strains|Injuries|Emergencies|Trauma|Acute Pain
Interventions: DRUG: Ibuprofen|DRUG: Lidocaine Patch 4%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Electronic Cigarettes on the Microcirculation of the Hand
Status: UNKNOWN
Conditions: Hand Injuries|Elective Hand Surgery
Interventions: DEVICE: No nicotine e-cigarette|DEVICE: Low dose nicotine e-cigarette|DEVICE: High dose nicotine e-cigarette
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Assessing the Feasibility of Integrating a Package of Maternal Nutrition Interventions Into Antenatal Care Services in Burkina Faso
Status: COMPLETED
Conditions: Maternal Dietary Diversity|Iron-Folic Acid Supplementation|Early Initiation of Breastfeeding
Interventions: BEHAVIORAL: Health Facility Level Interventions|BEHAVIORAL: Community Level Interventions|BEHAVIORAL: Health System Level Interventions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Phase III Trial to Assess the Safety and Immunogenicity of a HIPRA's Candidate Booster Vaccination Against COVID-19.
Status: COMPLETED
Conditions: COVID-19|SARS-CoV-2 Acute Respiratory Disease
Interventions: BIOLOGICAL: COVID-19 Vaccine 40 ug/dose
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Acute Low Back Pain in the Emergency Department Treated With Osteopathic Manipulative Treatment Versus NSAIDs
Status: RECRUITING
Conditions: Low Back Pain
Interventions: DRUG: Ibuprofen|PROCEDURE: Osteopathic manipulative treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Liver and Spleen Stiffness Measured by TE and 2D-SWE for Diagnosis of GOV in Patients With cACLD
Status: RECRUITING
Conditions: Liver Cirrhosis|Liver Fibrosis|Portal Hypertension
Interventions: DIAGNOSTIC_TEST: Transient elastography (TE) and 2D-shear wave elastography (2D-SWE)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparing 4L Golytely to 2L Golytely With 15mg Bisacodyl Regimens for Inpatient Colonic Preparation
Status: WITHDRAWN
Conditions: Colonoscopy
Interventions: DRUG: Standard Bowel Prep|DRUG: 2L Golytely/bisacodyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mindful Movement Intervention for Post-MI Patients
Status: UNKNOWN
Conditions: Myocardial Infarction
Interventions: BEHAVIORAL: Tai Chi|OTHER: Health Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Imeglimin on QT/QTc Intervals in Healthy Subjects
Status: COMPLETED
Conditions: Qt Interval, Variation in
Interventions: DRUG: Placebo|DRUG: Imeglimin|DRUG: Moxifloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Magnetic Resonance (MR) Guided Focused Ultrasound in the Treatment of Brain Tumors
Status: COMPLETED
Conditions: Malignant Brain Tumors
Interventions: DEVICE: Non-invasive intervention with focused ultrasound (ExAblate 4000)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Carbidopa-Levodopa (CD-LD) ER Alone or in Combination With CD-LD IR to IPX066 Followed by IPX066 Extension Safety Study
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DRUG: IPX066
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: AESOPS Trial 2 (AESOPS-2): Availability of Opioid Harm
Status: COMPLETED
Conditions: Opioid Abuse
Interventions: BEHAVIORAL: Overdose Notification
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Cyclophosphamide and Vaccine Therapy With or Without Trastuzumab in Treating Patients With Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: BIOLOGICAL: allogeneic GM-CSF-secreting breast cancer vaccine|BIOLOGICAL: trastuzumab|DRUG: cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Decision Aid Website in Helping to Make Decisions About Fertility in Participants With Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Neoplasm|Colorectal Neoplasm|Female Reproductive System Neoplasm|Health Care Provider|Lymphoma|Plasma Cell Myeloma
Interventions: OTHER: Best Practice|OTHER: Educational Intervention|OTHER: Internet-Based Intervention|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Steroid Dosing by bioMARker Guided Titration in Critically Ill Patients With Pneumonia
Status: COMPLETED
Conditions: Pneumonia
Interventions: DRUG: Methylprednisolone|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Dysphotopsia Following Laser Peripheral Iridotomy
Status: COMPLETED
Conditions: Narrow Angle Patients at Risk for Angle Closure Glaucoma
Interventions: DEVICE: Neodymium-doped: Yttrium Aluminum Garnet (Nd:YAG) laser|PROCEDURE: Nd:YAG Laser Peripheral Iridotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Pharmacokinetic Study Of CP-945598 In Patients With NASH
Status: COMPLETED
Conditions: Non-Alcoholic Steatohepatitis(NASH)
Interventions: DRUG: Active treatment|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Radiation Therapy, Amifostine, and Chemotherapy in Treating Young Patients With Newly Diagnosed Nasopharyngeal Cancer
Status: COMPLETED
Conditions: Stage I Nasopharyngeal Keratinizing Squamous Cell Carcinoma AJCC v7|Stage I Nasopharyngeal Undifferentiated Carcinoma AJCC v7|Stage II Nasopharyngeal Keratinizing Squamous Cell Carcinoma AJCC v7|Stage II Nasopharyngeal Undifferentiated Carcinoma AJCC v7|Stage III Nasopharyngeal Keratinizing Squamous Cell Carcinoma AJCC v7|Stage III Nasopharyngeal Undifferentiated Carcinoma AJCC v7|Stage IV Nasopharyngeal Keratinizing Squamous Cell Carcinoma AJCC v7|Stage IV Nasopharyngeal Undifferentiated Carcinoma AJCC v7
Interventions: DRUG: Amifostine|DRUG: Cisplatin|DRUG: Fluorouracil|OTHER: Laboratory Biomarker Analysis|RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT