pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Home Use of Dual-light Photodynamic Therapy for Chronic Periodontitis
Status: RECRUITING
Conditions: Periodontal Diseases|Periodontitis|Plaque, Dental|Plaque Induced Gingivitis
Interventions: DEVICE: Lumoral treatment|OTHER: Standard oral hygiene self care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: HIIT Versus IMT on Modulating Blood Rheology in CAD Risk Factors
Status: UNKNOWN
Conditions: Coronary Artery Disease, Early-Onset
Interventions: DEVICE: Threshold Inspiration Muscle Training Device|DEVICE: Electronic Bicycle Ergometer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Effectiveness of Acupuncture and Doxylamine/Pyridoxine for Moderate to Severe Nausea and Vomiting in Pregnancy
Status: COMPLETED
Conditions: Nausea and Vomiting of Pregnancy
Interventions: DRUG: Diclectin|DRUG: Diclectin placebo|DEVICE: Active acupuncture|DEVICE: Sham acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Adverse Events, Change in Disease Activity, and How ABBV-706 Moves Through the Body When Intravenously (IV) Infused Alone or in Combination With IV Infused Budigalimab, Cisplatin, or Carboplatin in Adult Participants With Advanced Solid Tumors
Status: RECRUITING
Conditions: Advanced Solid Tumors
Interventions: DRUG: ABBV-706|DRUG: Cisplatin|DRUG: Budigalimab|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Interaction of Melatonin With MTNR1B Genotype on Glucose Control - Study 2
Status: COMPLETED
Conditions: Glucose|Circadian Rhythm|Melatonin|Genes|Light
Interventions: DRUG: placebo|DIETARY_SUPPLEMENT: melatonin|OTHER: bright light|OTHER: dim light
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: TIPS vs Endoscopic Therapy for Variceal Rebleeding in Cirrhotic Patients With Portal Vein Thrombosis
Status: RECRUITING
Conditions: Portal Vein Thrombosis|Liver Cirrhosis
Interventions: PROCEDURE: Transjugular intrahepatic portosystemic shunt|DRUG: Non-selective beta blockers|PROCEDURE: Endoscopic therapy|DRUG: Anticoagulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Efficacy and Safety of Ipragliflozin in Combination With Insulin in Subjects With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: ipragliflozin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CSD201202: A Study to Assess Nicotine Uptake From Electronic Nicotine Delivery System P12
Status: COMPLETED
Conditions: Smoking|Tobacco Use
Interventions: OTHER: ENDS Product A with 1.5% nicotine|OTHER: ENDS Product B with 1.5% nicotine|OTHER: ENDS Product C with 1.5% nicotine|OTHER: ENDS Product D with 1.5% nicotine|OTHER: ENDS Product E with 1.5% nicotine|OTHER: ENDS Product F with 1.5% nicotine|OTHER: ENDS Product G with 1.5% nicotine|OTHER: ENDS Product H with 1.5% nicotine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effects Of Breath And Stacking-Spirometry Incentive in Patients With Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson's Disease.
Interventions: OTHER: Breath-Stacking|OTHER: Incentive spirometry|DEVICE: 5000 Voldyne ® Sherwood Medical, USA|DEVICE: Silicone face mask
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Effect of Metformin on ABCB1 and AMPK Expression in Adolescents With Newly Diagnosed Acute Lymphoblastic Leukemia
Status: UNKNOWN
Conditions: Acute Lymphoblastic Leukemia
Interventions: DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Compare the PK, PD and Safety and Tolerability of a SC With an IV Formulation of ARGX-113 in Healthy Male Subjects
Status: COMPLETED
Conditions: Bioavailability Study
Interventions: DRUG: ARGX-113
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: An Efficacy and Safety Study of Alirocumab in Children and Adolescents With Heterozygous Familial Hypercholesterolemia
Status: COMPLETED
Conditions: Hypercholesterolaemia
Interventions: DRUG: Alirocumab SAR236553 (REGN727)|DRUG: Rosuvastatin|DRUG: Atorvastatin|DRUG: Simvastatin|DRUG: Pravastatin|DRUG: Lovastatin|DRUG: Fluvastatin|DRUG: Ezetimibe|DRUG: Cholestyramine|DRUG: Nicotinic acid|DRUG: Fenofibrate|DRUG: Omega-3 fatty acids|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate BMS-986165 Tablet Formulation Relative to BMS-986165 Capsule Formulation and the Effect of a High-Fat/ High-Calorie Meal and Increased Gastric pH on the BMS-986165 Tablet Formulation
Status: COMPLETED
Conditions: Systemic Lupus Erythematosus|Arthritic Psoriasis|Psoriasis|Inflammatory Bowel Diseases
Interventions: DRUG: BMS-986165 Capsule|DRUG: BMS-986165 Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transbronchial Mediastinal Cryobiopsy Combined With EBUS-TBNA in the Diagnosis of Mediastinal Lesions
Status: COMPLETED
Conditions: Mediastinal Lymphadenopathy
Interventions: PROCEDURE: EBUS-TBMCB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparative Study of the Pharmacokinetics of Rinsulin® Mix 30/70, Suspension for Subcutaneous Administration, 100 IU / ml (OJSC GEROPHARM-Bio, Russia) and Humulin® M3, Suspension for Subcutaneous Administration, 100 IU / ml (Lilly France, France) Using the Euglycemic Hyperinsulinemic Clamp Method
Status: COMPLETED
Conditions: Bioequivalence
Interventions: DRUG: Rinsulin® mix 30/70|DRUG: Humulin® M3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect of Prebiotic B-GOS on the Immune Function, Metabolism and Gut Microbiota of Elderly People
Status: COMPLETED
Conditions: Immunosenescence
Interventions: DIETARY_SUPPLEMENT: Bi2muno® GOS|DIETARY_SUPPLEMENT: Maltodextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Three Strategies Based on Vaginal Self-sampling Kit Send to Home of Unscreened Women for Cervical Cancer
Status: COMPLETED
Conditions: Cervical Cancer Screening|Cervical Cancer
Interventions: BEHAVIORAL: Self-sampling kit sent at home|BEHAVIORAL: Self-sampling kit sent at home + SMS reminder|BEHAVIORAL: Letter offering a self-sampling kit "on request"+ SMS reminder|BEHAVIORAL: SMS offering a self-sampling kit "on request"+ SMS reminder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: A Phase I-II Open Label Non-Randomized Study Using TL32711 for Patients With Acute Myelogenous Leukemia, Myelodysplastic Syndrome and Acute Lymphoblastic Leukemia
Status: TERMINATED
Conditions: Acute Myelogenous Leukemia
Interventions: DRUG: Birinapant
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Trial for Chemo-Resistant Gestational Trophoblastic Neoplasias With Pembrolizumab (CR-GTP)
Status: UNKNOWN
Conditions: Gestational Trophoblastic Neoplasia
Interventions: DRUG: Pembrolizumab Injection [Keytruda]
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Postpartum Visit Timing and the Effect on Visit Attendance
Status: COMPLETED
Conditions: Postpartum Disorder|Postpartum Depression|Postpartum Weight Retention|Breastfeeding|Satisfaction, Patient|Trust
Interventions: BEHAVIORAL: Early postpartum visit|BEHAVIORAL: Standard postpartum visit
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Trial of PCSK9 Inhibition in Patients With Acute Stroke and Symptomatic Intracranial Atherosclerosis
Status: RECRUITING
Conditions: Intracranial Atherosclerosis|Acute Ischemic Stroke|ICAS - Intracranial Atherosclerosis
Interventions: DRUG: Alirocumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Ultrasound-guided Corticosteroid Injection Versus Palpation-guided Injection for de Quervain's Disease
Status: COMPLETED
Conditions: De Quervain Disease
Interventions: PROCEDURE: US-guided injection|PROCEDURE: palpation-guided injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multiple Dose, Dose Escalation Trial of AEB1102 in Patients With AML or MDS
Status: COMPLETED
Conditions: Acute Myeloid Leukemia|Myelodysplastic Syndrome
Interventions: DRUG: Co-ArgI-PEG modified human arginase I
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Micro RNAs as a Marker of Aortic Aneurysm in Hereditary Aortopathy Syndromes
Status: COMPLETED
Conditions: Marfan Syndrome|Loeys-Dietz Syndrome|Thoracic Aortic Aneurysm and Dissection Syndromes|Ehlers-Danlos Type IV Syndrome|Turner Syndrome
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Examine the Feasibility of a Standardized Field Test for Marijuana Impairment: Laboratory Evaluations
Status: COMPLETED
Conditions: Marijuana Impairment
Interventions: DRUG: Low Dose THC Marijuana|DRUG: High Dose THC Marijuana|DRUG: Placebo Marijuana
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: 3D-printed Porous Titanium Alloy Cages Versus PEEK Cages in Patients With Osteoporosis
Status: UNKNOWN
Conditions: Osteoporosis|Degenerative Disc Disease|Degenerative Lumbar Spinal Stenosis|Degeneration Spine
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Palbociclib Combine With Anti-HER2 Therapy in Triple Positive ABC
Status: RECRUITING
Conditions: Breast Neoplasm Female
Interventions: DRUG: CDK4/6 inhibitor (Qilu),Trastuzumab (Hanquyou)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gene-Modified Immune Cells (FH-MCVA2TCR) in Treating Patients With Metastatic or Unresectable Merkel Cell Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Other Skin
Interventions: BIOLOGICAL: Autologous MCPyV-specific HLA-A02-restricted TCR-transduced CD4+ and CD8+ T-cells FH-MCVA2TCR|DRUG: Avelumab|BIOLOGICAL: Pembrolizumab|BIOLOGICAL: Interferon Gamma-1b
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Randomized Single-Blinded Study to Evaluate Safety and Immunogenicity of Recombinant Plague Vaccine With and Without Adjuvant
Status: COMPLETED
Conditions: Plague Vaccine
Interventions: BIOLOGICAL: rF1V vaccine (with Adjuvant)|BIOLOGICAL: rF1V vaccine (without Adjuvant)|BIOLOGICAL: rF1V vaccine (with Adjuvant)|BIOLOGICAL: rF1V vaccine (without Adjuvant)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Multi-peptide Vaccination Adjuvanted With XS15 in Acute Myeloid Leukemia Patients
Status: NOT_YET_RECRUITING
Conditions: Acute Myeloid Leukemia, Adult
Interventions: DRUG: Vaccines, Peptide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Whole Beans on Inflammation and Satiety
Status: COMPLETED
Conditions: Metabolic Syndrome
Interventions: OTHER: Couscous plus fiber|DIETARY_SUPPLEMENT: Grape seed extract|OTHER: Bean Soup
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effectiveness of an App Intervention to Reduce Postsurgical Symptom Distress in Patients With Vulvar Neoplasia
Status: COMPLETED
Conditions: Vulvar Neoplasm
Interventions: OTHER: WOMAN-PRO III|OTHER: Three counselling sessions with gynaecology-oncology nurses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Assess the Effects of Renal Impairment on the Pharmacokinetics, Safety, and Tolerability of Intranasally Administered Esketamine
Status: COMPLETED
Conditions: Renal Impairment|Healthy
Interventions: DRUG: Esketamine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Learn More About How Well Elinzanetant Works and How Safe it is for the Treatment of Vasomotor Symptoms (Hot Flashes) That Are Caused by Hormonal Changes Over 52 Weeks in Women Who Have Been Through the Menopause
Status: COMPLETED
Conditions: Vasomotor Symptoms Associated With Menopause|Hot Flashes
Interventions: DRUG: Elinzanetant (BAY3427080)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Development of a New Early Detection Test to Reduce Racial Disparities in Endometrial Cancer (EC) Death Rates
Status: COMPLETED
Conditions: Endometrial Carcinoma
Interventions: PROCEDURE: Biospecimen Collection|BEHAVIORAL: Focus Group|OTHER: Survey Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Spitex-SpiTal-Autonomie-Reha-Kraft
Status: TERMINATED
Conditions: Osteoporosis|Frailty|Hip Fractures
Interventions: OTHER: STARK intervention|OTHER: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: ELectrosurgical Bipolar Devices VS Conventional Electro-cauterization in Breast Surgery
Status: COMPLETED
Conditions: Seroma as Procedural Complication
Interventions: DEVICE: electrosurgical bipolar sealing devices|PROCEDURE: conventional suture and tie
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Reduced Intensity Conditioning With Clofarabine, Antithymocyte Globulin (ATG), Total Lymphoid Irradiation (TLI) Followed by Allogeneic Stem Cell Transplant
Status: COMPLETED
Conditions: Acute Myeloid Leukemia|Myelodysplastic Syndrome|Acute Lymphocytic Leukemia|Relapsed/Refractory Chronic Lymphocytic Leukemia|Relapsed/Refractory Non Hodgkin's Lymphoma|Hodgkins Disease|Relapsed Refractory Multiple Myeloma
Interventions: DRUG: Antithymocyte Globulin|DRUG: Clofarabine|DRUG: Clofarabine|DRUG: Clofarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neuroplasticity in Maternal Opioid Use Disorder (OUD)
Status: RECRUITING
Conditions: Opioid Use Disorder
Interventions: BEHAVIORAL: ERPs with electroencephalography (EEG)|BEHAVIORAL: MIO
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endoscopic Partial Adenoidectomy Versus Total Adenoidectomy Regarding Rate of Recurrence and Relief of Symptoms
Status: RECRUITING
Conditions: Adenoidal Hypertrophy
Interventions: DEVICE: Endoscopic adenoidectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Exploring Empathy and Compassion Using Digital Narratives
Status: RECRUITING
Conditions: Mental Disorders, Severe|Mental Illness|Stigma, Social|Compassion|Empathy
Interventions: OTHER: Digital storytelling group|OTHER: Social marketing/fundraising group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of RO7172508 in Patients With Locally Advanced and/or Metastatic CEA-Positive Solid Tumors
Status: TERMINATED
Conditions: Solid Tumors
Interventions: DRUG: RO7172508|DRUG: Obinutuzumab|DRUG: Tocilizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of a Probiotic Fermented Milk on Functional Constipation in Adults
Status: COMPLETED
Conditions: Constipation
Interventions: DIETARY_SUPPLEMENT: Probiotics fermented milk|DIETARY_SUPPLEMENT: Nutrient drink
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Valutazione All'Ingresso Del Rischio Nutrizionale in Pazienti Ricoverati Nel Reparto di Medicina Interna (AMIDO)
Status: COMPLETED
Conditions: Malnutrition|Hospitalized Patient
Interventions: OTHER: Nutritional intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effects of Nitric Oxide for Inhalation in Myocardial Infarction Size
Status: COMPLETED
Conditions: Acute Myocardial Infarction
Interventions: DRUG: Nitric Oxide|DRUG: MI size at 48-72 hours
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Lapatinib and Trastuzumab With or Without Endocrine Therapy
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Lapatinib|DRUG: Trastuzumab|DRUG: Endocrine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chest Physical Therapy in Patients Waiting for Allogeneic Hematopoietic Stem Cell Transplantation"
Status: COMPLETED
Conditions: Allogeneic Hematopoietic Stem Cell Transplantation
Interventions: OTHER: chest physical therapy|OTHER: routine medical treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Acupuncture on Nerve Pain Caused by Taxane (Chemotherapy) Treatment
Status: RECRUITING
Conditions: Breast Cancer|Taxane-Induced Peripheral Neuropathy
Interventions: PROCEDURE: Real Acupuncture|OTHER: Sham Acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Genicular Nerve Block Versus Its Combination With Infiltration Between Popliteal Artery and Capsule of Posterior Knee
Status: RECRUITING
Conditions: Postoperative Pain
Interventions: PROCEDURE: GNB plus standard analgesia|PROCEDURE: GNB plus IPACK block plus standard analgesia|DRUG: standard analgesia (paracetamol and meloxicam)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Prospective Comparison Between Ureteral Stent and Nephrostomy Tube for an Urgent Drainage of Obstructed Kidney
Status: UNKNOWN
Conditions: Kidney Disease
Interventions: DEVICE: nephrostomy tube and ureteral stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Feasibility Study of the Millipede Transcatheter Annuloplasty Ring System in Patients With Functional Mitral Regurgitation
Status: ACTIVE_NOT_RECRUITING
Conditions: Mitral Regurgitation Functional|Mitral Valve Disease|Cardiovascular Diseases
Interventions: DEVICE: Millipede Transcatheter Annuloplasty Ring System (Millipede System)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Safety and Efficacy of IMM01 Plus Tislelizumab in Patients With Advanced Solid Tumors and Lymphomas
Status: RECRUITING
Conditions: Solid Tumor|Classic Hodgkin Lymphoma
Interventions: DRUG: IMM01|DRUG: Tislelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Short-term Effect of Podiatric Callus Debridement on Plantar Pressure in Diabetic Neuropathic Patients
Status: COMPLETED
Conditions: Diabetic Neuropathies|Plantar Callus
Interventions: PROCEDURE: Callus debridement
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fibroblast Growth Factor Regeneration of Tympanic Membrane Perforations
Status: RECRUITING
Conditions: Tympanic Membrane Perforation
Interventions: DRUG: FGF-2|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Respiratory Variability in Aortic Blood Velocity Measured by Suprasternal View as an Indicator of Fluid Responsiveness
Status: COMPLETED
Conditions: Cardiovascular System
Interventions: DEVICE: Fluid challenge with 250 ml of Ringer Lactate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Cryobiopsy or Forceps Biopsy During Semirigid Thoracoscopy: a Comparative Study
Status: COMPLETED
Conditions: Pleural Effusion|Pleural Diseases
Interventions: DEVICE: cryobiopsy (Autoclavable cryoprobe 20416-032 (ERBE, Germany) Flexible FB-55CD-1 Olympus forceps
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Compare the Different Routes of Administration of Misoprostol During Medicinal Abortion Between 7 and 9 Weeks of Amenorrhoea (SA)
Status: WITHDRAWN
Conditions: Misoprostol|Drug-induced Abortion
Interventions: BIOLOGICAL: Assess the efficacy and side effects of Misoprostol according to the route of administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Selective Head-and-neck Cooling on Biomarker Levels and Symptom Rating Following a Boxing Bout
Status: RECRUITING
Conditions: Repetitive Head Impact|Selective Head and Neck Cooling
Interventions: DEVICE: PolarCap System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study to Evaluate and Compare the Bioequivalence of Two Abaloparatide-sMTS Treatments in Healthy Women.
Status: COMPLETED
Conditions: Osteoporosis
Interventions: COMBINATION_PRODUCT: abaloparatide-sMTS (Patheon)|COMBINATION_PRODUCT: abaloparatide-sMTS (Kindeva)|COMBINATION_PRODUCT: abaloparatide-sMTS (Patheon)|COMBINATION_PRODUCT: abaloparatide-sMTS (Patheon)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Compare TP-434 and Ertapenem in Community-acquired Complicated Intra-abdominal Infections
Status: COMPLETED
Conditions: Complicated Intra-abdominal Infection
Interventions: DRUG: TP-434|DRUG: Ertapenem|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Switching to Certican® in Viremia of Hepatitis C Virus in Adult Renal Allograft Recipients
Status: COMPLETED
Conditions: Renal Allograft|Hepatitis C
Interventions: DRUG: Everolimus|DRUG: Cyclosporine|DRUG: Tacrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluating the Pharmacokinetic Interaction Between AD-2101 and AD-2102
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: AD-2101|DRUG: AD-2102|DRUG: AD-2101 + AD-2102
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Posoleucel (Formerly Known as ALVR105; Viralym-M) in Kidney Transplant Patients With BK Viremia
Status: COMPLETED
Conditions: BK Virus Nephropathy|BK Virus Infection
Interventions: BIOLOGICAL: Posoleucel (formerly known as ALVR105) cells|BIOLOGICAL: Placebo (visually identical to Posoleucel)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cemented vs. Cementless TKA
Status: TERMINATED
Conditions: Total Knee Arthroplasty (TKA)
Interventions: PROCEDURE: Cementless Total Knee Arthroplasty|PROCEDURE: Cemented Total Knee Arthroplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Phase III Randomized, Double-Blind Study of Potassium Phosphate Vs Potassium Citrate for Absorptive Hypercalciuria
Status: COMPLETED
Conditions: Hypercalciuria|Kidney Calculi
Interventions: DRUG: potassium citrate|DRUG: potassium phosphate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Use of Bovine Bone Graft and Titanium-Platelet Rich Fibrin in Maxillary Sinus Augmentation
Status: COMPLETED
Conditions: Sinus Disease|Maxillary Sinus Disease
Interventions: PROCEDURE: maxillary sinus augmentation and implant placement|PROCEDURE: Maxillary sinus augmentation with bovine bone graft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Head and Neck Squamous Cell Carcinoma (HNSCC)PET-CT Pilot Study
Status: RECRUITING
Conditions: Head and Neck Squamous Cell Carcinoma
Interventions: DRUG: 18-F FDG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Phase I Study of the Safety and Pharmacokinetics of Recombinant CD4 (rCD4) in Infants and Children Infected With or at Risk for HIV Infection
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: CD4 Antigens
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vaccine Therapy in Treating Patients With Stage IV Hormone Receptor Positive Breast Cancer
Status: TERMINATED
Conditions: HER2-positive Breast Cancer|Male Breast Cancer|Recurrent Breast Cancer|Stage IV Breast Cancer
Interventions: BIOLOGICAL: HER-2/neu peptide vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Multifunctional Cataract-assisted Retractor in Complicated Cataract Surgery
Status: UNKNOWN
Conditions: Subluxation of Lens|Surgical Instruments，Cataract
Interventions: DEVICE: Multifunctional Cataract-assisted Retractor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nilotinib and Combination Chemotherapy in Treating Patients With Newly Diagnosed Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia or Blastic Phase Chronic Myelogenous Leukemia
Status: WITHDRAWN
Conditions: B-cell Adult Acute Lymphoblastic Leukemia|Blastic Phase Chronic Myelogenous Leukemia|Chronic Myelogenous Leukemia, BCR-ABL1 Positive|Philadelphia Chromosome Positive Adult Precursor Acute Lymphoblastic Leukemia|Untreated Adult Acute Lymphoblastic Leukemia
Interventions: DRUG: nilotinib|BIOLOGICAL: rituximab|DRUG: cyclophosphamide|DRUG: doxorubicin hydrochloride|DRUG: vincristine sulfate|DRUG: methotrexate|DRUG: cytarabine|DRUG: prednisone|DRUG: mesna|DRUG: dexamethasone|DRUG: leucovorin calcium
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Safety and the Phosphate Binding Capacity of Renazorb
Status: COMPLETED
Conditions: Safety|Phosphate Binding Capacity
Interventions: DRUG: Renazorb 1500 mg/day|DRUG: Renazorb 3000 mg/day|DRUG: Renazorb 4500 mg/day|DRUG: Renazorb 6000 mg/day
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A New Treatment of Retinitis Pigmentosa
Status: UNKNOWN
Conditions: Retinitis Pigmentosa
Interventions: PROCEDURE: retrobulbar injection of autoserum|PROCEDURE: retrobulbar injection of placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of NGR-hTNF in Combination With Doxorubicin in Solid Tumors
Status: COMPLETED
Conditions: Cancer
Interventions: DRUG: NGR-hTNF|DRUG: Doxorubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial Evaluating TKR Compared to BKR Performed Using Stryker's Mako Robot
Status: TERMINATED
Conditions: Non-inflammatory Degenerative Joint Disease
Interventions: DEVICE: Stryker Triathlon Primary Total Knee System|DEVICE: Restoris MCK Multicompartmental Knee System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TVB- 2640 in Combination With Bevacizumab in Patients With First Relapse of High Grade Astrocytoma
Status: COMPLETED
Conditions: Astrocytoma
Interventions: DRUG: Bevacizumab|DRUG: TVB-2640
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hysteroscopic Septoplasty by Different Modalities
Status: COMPLETED
Conditions: Septate Uterus|Recurrent Pregnancy Loss|Subfertility
Interventions: PROCEDURE: Hysteroscopic septoplasty with scissors|PROCEDURE: Hysteroscopic septoplasty with resectoscope
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Investigating tDCS as a Treatment for Unipolar and Bipolar Depression
Status: COMPLETED
Conditions: Unipolar Depression|Bipolar Depression
Interventions: DEVICE: Sham tDCS device|DEVICE: Soterix tDCS device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Nonintubated Thoracoscopic Lobectomy on Lung Protection
Status: UNKNOWN
Conditions: Non-small Cell Lung Cancer|Lung Function Decreased|Tracheal Intubation Morbidity
Interventions: PROCEDURE: Nonintubated thoracoscopic lobectomy|PROCEDURE: Intubated thoracoscopic lobectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Impacts of Aldosterone Blockade on Myocardial Remodeling in Hypertensive Patients With Diastolic Failing Heart
Status: COMPLETED
Conditions: Diastolic Heart Failure
Interventions: DRUG: aldactone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Outcomes of Mesh Fixation Versus Non Fixation in Laparoscopic TAPP Inguinal Hernia Repair
Status: COMPLETED
Conditions: Hernia, Inguinal
Interventions: PROCEDURE: Laparoscopic TAPP inguinal hernia repair
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Low Intensity Conditioning and Immunotherapy for High-Risk Cancers of the Blood
Status: TERMINATED
Conditions: Leukemia|Lymphoma, Low-Grade|Lymphoma, Non-Hodgkin's|Multiple Myeloma|Myelodysplastic Syndromes
Interventions: PROCEDURE: Reduced intensity conditioning|PROCEDURE: Prophylactic donor leukocyte infusions
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: ECT
Clinical trial: Subacromial Bursa Re-Implantation After Rotator Cuff Repair
Status: ACTIVE_NOT_RECRUITING
Conditions: Rotator Cuff Injuries
Interventions: PROCEDURE: Experimental group(Bursa Implantation)|PROCEDURE: Control Group(Standard of Care)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Medico-economic Study of Patient Matched Cutting Blocks (Ancillary) MyKnee ® LBS During Knee Arthroplasty GMK ®.
Status: UNKNOWN
Conditions: Osteoarthritis
Interventions: DEVICE: prosthesis GMK ® without the ancillary MyKnee ® LBS|DEVICE: Matched patient cutting blocks MyKnee ® LBS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Glutamine in Preventing Oral Mucositis in Patients Receiving Chemotherapy for Sarcoma
Status: WITHDRAWN
Conditions: Childhood Malignant Fibrous Histiocytoma of Bone|Sarcoma
Interventions: DRUG: glutamine|PROCEDURE: chemoprotection|PROCEDURE: management of therapy complications|PROCEDURE: therapeutic nutritional supplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Multi-clinic Action Trial to Control Hyperglycemia and Hypertension
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: BEHAVIORAL: Home Based Enhanced Education|BEHAVIORAL: Clinic Based Enhanced Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Clinical Trial of PRAX-222 in Pediatric Participants With Early Onset SCN2A Developmental and Epileptic Encephalopathy
Status: ACTIVE_NOT_RECRUITING
Conditions: SCN2A-DEE|Epilepsy
Interventions: DRUG: PRAX-222 - Initial Dose|DRUG: PRAX-222 - Initial Ascending Doses|DRUG: PRAX-222 - Optional Ascending Doses|DRUG: PRAX-222 - Fixed Doses|PROCEDURE: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Leucine for Depression Study (L-DEP)
Status: TERMINATED
Conditions: Depression
Interventions: DIETARY_SUPPLEMENT: leucine|OTHER: PO placebo|BIOLOGICAL: lipopolysaccharide (LPS)|OTHER: IV placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Prevention of the Minor Digestive Disorders by Lactobacillus Reuteri Supplementation
Status: COMPLETED
Conditions: Minor Digestive Disorders
Interventions: DIETARY_SUPPLEMENT: Lactobacillus reuteri|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Ruxolitinib Phosphate in Reducing Fatigue in Patients With Chronic Lymphocytic Leukemia
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Lymphocytic Leukemia
Interventions: OTHER: Questionnaire Administration|DRUG: Ruxolitinib Phosphate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Improving Asthma Care Together (IMPACT): A Shared Management Pilot Study
Status: COMPLETED
Conditions: Asthma in Children
Interventions: BEHAVIORAL: Improving Asthma Care Together (IMPACT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: β-elemene Combine With EGFR-TKI for Advanced EGFR-TKI-resistant NSCLC
Status: UNKNOWN
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: β-elemene|DRUG: EGFR-TKIs(Erlotinib, Gefitinib and Icotinib)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of New and 3-Month-Old Toothbrush in the Removal of Plaque in Children
Status: COMPLETED
Conditions: Plaque Removal
Interventions: OTHER: old toothbrush|OTHER: New tooth brush
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effectiveness of a Team-based Follow-up Program in General Practice Among People With Chronic Conditions
Status: COMPLETED
Conditions: Diabetes Type 2|COPD
Interventions: BEHAVIORAL: Guided Self-Determination|BEHAVIORAL: Standard care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: CROSSOVER STUDY OF ON-DEMAND PREP FORMULATIONS COMPARING RECTAL AND ORAL TENOFOVIR
Status: NOT_YET_RECRUITING
Conditions: Tenofovir
Interventions: DRUG: Oral F/TDF Pills|DRUG: TFV rectal douche
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multicentre, Randomised, Open-label, Controlled, 12-month Follow-up Study to Assess Impact on Renal Function of an Immunosuppression Regimen Based on Tacrolimus Minimisation in Association With Everolimus in de Novo Liver Transplant Recipients.
Status: COMPLETED
Conditions: Liver Transplant
Interventions: DRUG: Minimisation of TAC|DRUG: TAC + MMF + corticosteroids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study of DS-5565 for Treatment of Fibromyalgia Pain in Subjects With Chronic Kidney Disease
Status: COMPLETED
Conditions: Fibromyalgia
Interventions: DRUG: DS-5565|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Pioglitazone, a PPARgamma Receptor Agonist, on the Abuse Liability of Oxycodone
Status: COMPLETED
Conditions: Opioid Abuse
Interventions: DRUG: pioglitazone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Simulation Based Workshop in an Anesthesia Residency Program
Status: COMPLETED
Conditions: Cerebrospinal Fluid Drainage Catheter
Interventions: OTHER: Simulation-based learning|OTHER: interactive problem based learning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Impact of Omega 3 Fatty Acid Supplementation on Aromatase in Obese Subjects
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Letrozole|DIETARY_SUPPLEMENT: Fish Oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Economic Evaluation of Robot-assisted Laparoscopic Radical Prostatectomy vs Conventional Laparoscopic Radical Prostatectomy and Open Retropubic Radical Prostatectomy in Prostate Cancer: a Real-life Study Based on the French National Healthcare Data System (SNDS)
Status: UNKNOWN
Conditions: Prostate Cancer
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of BIA 9-1067 to Investigate Its Effect on Levodopa Pharmacokinetic
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: DRUG: BIA 9-1067 5 mg|DRUG: Entacapone|DRUG: Placebo|DRUG: levodopa/carbidopa|DRUG: BIA 9-1067 15 mg|DRUG: BIA 9-1067 30 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Feasibility of Normothermic Machine Perfusion to Preserve and Evaluate Orphan Livers
Status: ACTIVE_NOT_RECRUITING
Conditions: Liver Transplantation
Interventions: DEVICE: Normothermic Liver perfusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigate Linaprazan Glurate/Linaprazan in Healthy Subjects
Status: ACTIVE_NOT_RECRUITING
Conditions: GERD
Interventions: DRUG: Linaprazan Glurate 25 mg|DRUG: Linaprazan Glurate 50 mg|DRUG: Linaprazan Glurate 75 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transcranial Direct Current Stimulation (tDCS) in Chronic Post-Stroke Apathy
Status: TERMINATED
Conditions: Apathy|Stroke
Interventions: DEVICE: Transcranial Direct Current Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Empowerment-based Complementary and Alternative Medicine (ECAM)
Status: NOT_YET_RECRUITING
Conditions: Diabetes
Interventions: OTHER: Experimental: Empowerment Application for CAM Health Education|OTHER: Written Paper for CAM Health Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Feasibility and Safety of No-scar Transanal Total Mesorectal Excision for Rectal Cancer
Status: COMPLETED
Conditions: Rectal Cancer|Surgery
Interventions: PROCEDURE: no-scar transanal total mesorectal excision(TME)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Will Radiation/Chemotherapy Treatment of Cervical Cancer Work Better With Medication That May Improve Anemia?
Status: UNKNOWN
Conditions: Anemia|Cervix Neoplasms
Interventions: DRUG: NESP - Novel Erythropoiesis Stimulating Protein
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: 3F8/GM-CSF Immunotherapy Plus 13-Cis-Retinoic Acid for Consolidation of Second or Greater Remission of High-Risk Neuroblastoma
Status: TERMINATED
Conditions: Neuroblastoma
Interventions: BIOLOGICAL: 3F8/GM-CSF Immunotherapy Plus 13-Cis-Retinoic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Thorough Corrected QT Interval Trial
Status: COMPLETED
Conditions: Dyslipidemia
Interventions: DRUG: K-877 Low Dose|DRUG: Moxifloxacin|OTHER: Placebo|DRUG: K-877 High Dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Tolerability, Safety, and Activity of SRX246 in Irritable Subjects With Huntington's Disease
Status: COMPLETED
Conditions: Irritable Mood|Huntington's Disease
Interventions: DRUG: SRX246|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: sEmg Biofeedback Training in Individuals With Subacromial Pain Syndrome
Status: UNKNOWN
Conditions: Shoulder Pain
Interventions: OTHER: sEmg biofeedback training|OTHER: Strength training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Acupressure Application on Patients' Nausea, Vomiting, Pain, and Sleep Quality
Status: COMPLETED
Conditions: Postoperative Complications
Interventions: DEVICE: acupressure wristband|DEVICE: placebo wristband
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Topical Gentamicin on the Prevention of Peritoneal Dialysis Related Infection
Status: UNKNOWN
Conditions: Peritoneal Dialysis-related Infection
Interventions: DRUG: Mupirocin|DRUG: Gentamicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Montelukast Added to Standard Therapy for Acute Asthma in Children Age 6-14 Years
Status: TERMINATED
Conditions: Asthma
Interventions: DRUG: Montelukast 5-mg orally added to standard therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Food Effect of Single-dose Bioavailability of Pracinostat in Healthy Adult Subjects
Status: COMPLETED
Conditions: Healthy Volunteers|Moderate to Heavy Smokers|Non-smokers
Interventions: DRUG: pracinostat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER