pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: High Intensity Interval Training and Hypoxic Conditioning in Obese Patients
Status: UNKNOWN
Conditions: Obesity
Interventions: OTHER: High intensity interval training N|OTHER: High intensity interval training H|OTHER: Constant load exercise training N|OTHER: Constant load exercise training H|OTHER: Hypoxic conditioning at rest|OTHER: Normoxic conditioning at rest
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Catalyst CSR Shoulder System for Semi or Total Shoulder Arthroplasty
Status: RECRUITING
Conditions: Osteoarthritis Shoulder|Avascular Necrosis of the Head of Humerus|Rheumatoid Arthritis Shoulder
Interventions: DEVICE: Catalyst CSR Total Shoulder System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigation of IOP and Tolerability of Bimatoprost 0.01% and Tafluprost Unit Dose Preservative Free 15 Microgram/ml
Status: UNKNOWN
Conditions: Ocular Hypertension|Glaucoma
Interventions: DRUG: Preserved Bimatoprost 0.01%|DRUG: Tafluprost Unit Dose Preservative Free 15microgram/ml
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Evaluate the Efficacy and Safety of FB1006 in the Treatment of ALS Patients
Status: RECRUITING
Conditions: Sporadic and Familial Amyotrophic Lateral Sclerosis
Interventions: DRUG: FB1006|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Post Operative Pain Following Reciprocating and Rotary Heat-treated NiTi Instrumentation of Root Canals: a Randomized Controlled Clinical Trial
Status: UNKNOWN
Conditions: Root Canal Infection
Interventions: DEVICE: root canal rotary files
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Glycemic Control Evaluation of Glimepiride Versus Rimonabant on Top of Metformin in Type 2 Diabetes
Status: TERMINATED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Rimonabant|DRUG: Glimepiride|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vagus Nerve Stimulation for Post-COVID Syndrome
Status: COMPLETED
Conditions: Long COVID|Vagus Nerve Stimulations|Heart Rates|Autonomic Nervous System Disorders
Interventions: DEVICE: Auricular transcutaneous vagus nerve stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Testing a Family Service Navigator Program for Low-resourced Families of Young Children With Autism Spectrum Disorder
Status: RECRUITING
Conditions: Autism Spectrum Disorder|Mental Health Services
Interventions: BEHAVIORAL: Access to a Family Service Navigator and Treatment Support System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Influence of Mechanical Ventilation Modes on the Efficacy of Nebulized Bronchodilator
Status: UNKNOWN
Conditions: COPD|Asthma
Interventions: DRUG: salbutamol sulfate and ipratropium bromide|DEVICE: Mesh nebulization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intraperitoneal Hyperthermic Chemotherapy in Epithelial Ovarian Carcinoma
Status: UNKNOWN
Conditions: Epithelial Ovarian Carcinoma|Figo Stage IIIC
Interventions: PROCEDURE: hyper thermic chemo + surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety of an Inactivated SARS-CoV-2 Vaccine Coadministered With Two Attenuated Vaccines
Status: NOT_YET_RECRUITING
Conditions: SARS-CoV-2 Infection|Varicella|Measles|Mumps|Rubella
Interventions: BIOLOGICAL: Inactivated SARS-CoV-2 vaccine coadministered with vricella vaccine|BIOLOGICAL: Inactivated SARS-CoV-2 vaccine coadministered with MMR|BIOLOGICAL: Inactivated SARS-CoV-2 vaccine administered alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Randomized Study of Adjuvant Radiotherapy After Curative Resection of HCC With Narrow Margin (RAISE)
Status: RECRUITING
Conditions: Hepatocellular Carcinoma|Radiotherapy|Hepatectomy
Interventions: RADIATION: Surgery-radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of Burosumab Versus Oral Phosphate and Active Vitamin D Treatment in Pediatric Patients With XLH
Status: COMPLETED
Conditions: X-Linked Hypophosphatemia
Interventions: BIOLOGICAL: burosumab|DRUG: Oral Phosphate Supplement|DRUG: active vitamin D
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Action Against Malnutrition Through Agriculture (AAMA) Plus MNP Study
Status: COMPLETED
Conditions: Anemia
Interventions: DIETARY_SUPPLEMENT: MNP (micro-nutrient powders)|OTHER: AAMA project activities (HFP and IYCF BCC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Fractional Flow Reserve Versus Angiography for Guiding Selective Percutaneous Coronary Intervention in ST-segment Elevation Myocardial Infarction
Status: UNKNOWN
Conditions: Fractional Flow Reserve|ST-segment Elevation Myocardial Infarction|Percutaneous Coronary Intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Alvocidib and Oxaliplatin With or Without Fluorouracil and Leucovorin Calcium in Treating Patients With Relapsed or Refractory Germ Cell Tumors
Status: COMPLETED
Conditions: Recurrent Extragonadal Seminoma|Recurrent Malignant Extragonadal Germ Cell Tumor|Recurrent Malignant Extragonadal Non-Seminomatous Germ Cell Tumor|Recurrent Malignant Testicular Germ Cell Tumor|Recurrent Ovarian Germ Cell Tumor|Stage III Testicular Cancer|Stage IV Extragonadal Non-Seminomatous Germ Cell Tumor|Stage IV Extragonadal Seminoma|Stage IV Ovarian Germ Cell Tumor
Interventions: DRUG: Alvocidib Hydrochloride|DRUG: Fluorouracil|DRUG: Leucovorin Calcium|DRUG: Oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrabrief Pulsewidth Electroconvulsive Therapy (ECT)
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: PROCEDURE: bilateral ultrabrief ECT|PROCEDURE: bilateral standard ECT|PROCEDURE: right-unilateral ultrabrief ECT|PROCEDURE: right-unilateral standard ECT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Is Sjögren's Syndrome Associated With Meibomian Gland Dysfunction ?
Status: UNKNOWN
Conditions: Sjögren's Syndrome|Meibomian Gland Dysfunction
Interventions: DRUG: Tears Naturale Forte|DRUG: liposic
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Amphotericin-B and Voriconazole for Pulmonary Blastomycosis
Status: TERMINATED
Conditions: Blastomycosis
Interventions: DRUG: amphotericin-B|DRUG: voriconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radiofrequency Ablation for Patients With Esophageal Squamous Cell Neoplasia
Status: COMPLETED
Conditions: ESOPHAGEAL SQUAMOUS CELL CARCINOMA
Interventions: DEVICE: Radiofrequency Ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Trial: Low-Dose Radiation + SBRT + Sintilimab + Chemotherapy vs. Sintilimab + Chemotherapy in Locally Advanced or Metastatic Squamous Cell Lung Cancer
Status: RECRUITING
Conditions: Lung Squamous Cell Carcinoma
Interventions: RADIATION: low-dose radiation therapy and stereotactic body radiation therapy|DRUG: chemotherapy|DRUG: Sintilimab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Vitamin D Status and Multiple Mega-dose Supplementation on Health Care Disparities in Perioperative Patients With Hepatocellular Carcinoma Receiving Hepatectomy
Status: NOT_YET_RECRUITING
Conditions: Hepatocellular Carcinoma|Liver Function|Postoperative Complications
Interventions: OTHER: Vitamin D|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Abemaciclib for Bone and Soft Tissue Sarcoma With Cyclin-Dependent Kinase (CDK) Pathway Alteration
Status: RECRUITING
Conditions: Chondrosarcoma|Osteosarcoma|Soft Tissue Sarcoma
Interventions: DRUG: Abemaciclib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Pharmacists' Training on Oral Anticoagulant Counseling
Status: COMPLETED
Conditions: Deep Vein Thrombosis|Pulmonary Embolism|Atrial Fibrillation
Interventions: BEHAVIORAL: Counseling training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Treatment of Implant-retained Mandibular Overdentures for Edentulous Patients
Status: UNKNOWN
Conditions: Edentulous
Interventions: PROCEDURE: implant-retained overdentures
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of Clascoterone Solution in Treatment of Male Pattern Hair Loss (SCALP2)
Status: RECRUITING
Conditions: Alopecia, Androgenetic
Interventions: DRUG: Clascoterone 5% solution|DRUG: Vehicle solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Inflammatory Mediators in Obstructive Sleep Apnoea Syndrome; Mechanisms of Production and the Effect of Long Term Antioxidants Administration
Status: UNKNOWN
Conditions: Obstructive Sleep Apnea Syndrome
Interventions: DEVICE: n-CPAP|DEVICE: Oxygen supplementation|DRUG: Vitamin A, Vitamin C, Vitamin E, Allopurinol, N-Acetylcysteine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Semi-automatic Download of Prostate Biopsy Cores While Keeping the Orientation, Unfolding and Unity of the Sample
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DEVICE: NaviGo Bx™|PROCEDURE: biopsy sponge pad
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: INTEGRATE-D: A Pilot Test to Support Integration of Medical and Psychosocial Care for People With Type II Diabetes
Status: COMPLETED
Conditions: Type II Diabetes|Primary Health Care|Behavioral Health
Interventions: BEHAVIORAL: INTEGRATE-D
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Hydrocortisone for COVID-19 and Severe Hypoxia
Status: COMPLETED
Conditions: Covid-19|Hypoxia
Interventions: DRUG: Hydrocortisone|DRUG: Sodium Chloride 9mg/mL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess Efficacy and Safety of XC221 200 mg in the Treatment of Influenza or Other ARVI
Status: COMPLETED
Conditions: Influenza|Acute Respiratory Viral Infections
Interventions: DRUG: XC221|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Chemohormonal Therapy Followed by Salvage Surgery for High Risk PSA
Status: TERMINATED
Conditions: Prostate Cancer
Interventions: DRUG: Androgen Ablation|DRUG: Cabazitaxel|DRUG: Salvage Therapy|DRUG: Neoadjuvant Treatment - Hormonal Therapy|DRUG: Neoadjuvant Treatment - Cabazitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A First in Human Study to Evaluate the Safety, Tolerability and Pharmacokinetics of Single and Multiple Ascending Doses of Inhaled ETD002 in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: ETD002 - single dose|DRUG: Placebo - single dose|DRUG: ETD002 - 7 day repeat dose|DRUG: Placebo - 7 day repeat dose|DRUG: ETD002 - 14 day repeat dose|DRUG: Placebo - 14 day repeat dose|DRUG: Salbutamol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Effect of Rosuvastatin (CRESTOR®) on High Density Lipoprotein Kinetics in Patients With the Metabolic Syndrome
Status: COMPLETED
Conditions: Metabolic Syndrome|Dyslipidemia
Interventions: DRUG: Rosuvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy, Safety and Pharmacokinetics of Treprostinil Palmitil Inhalation Powder in Participants With Pulmonary Arterial Hypertension
Status: RECRUITING
Conditions: Pulmonary Arterial Hypertension
Interventions: DRUG: Treprostinil Palmitil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare Tenofovir Disoproxil Fumarate Versus Adefovir Dipivoxil for the Treatment of HBeAg-Positive Chronic Hepatitis B
Status: COMPLETED
Conditions: Chronic Hepatitis B
Interventions: DRUG: TDF|DRUG: ADV|DRUG: TDF placebo|DRUG: ADV placebo|DRUG: FTC/TDF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Evaluation of Handling Characteristics of Two Adrenaline Autoinjectors,EpiPen in Comparison With Jext
Status: COMPLETED
Conditions: Handling of Auto-injectors
Interventions: DRUG: Adrenaline auto-injector
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of BLD-0409 in Healthy Subjects
Status: COMPLETED
Conditions: Chronic Liver Disease|NASH - Nonalcoholic Steatohepatitis
Interventions: DRUG: BLD-0409|DRUG: Control: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Oxaliplatin, Ifosfamide and Etoposide in Treating Young Patients With Recurrent or Refractory Solid Tumors or Lymphoma
Status: TERMINATED
Conditions: Angioimmunoblastic T-cell Lymphoma|B-cell Childhood Acute Lymphoblastic Leukemia|B-cell Chronic Lymphocytic Leukemia|Childhood Burkitt Lymphoma|Childhood Diffuse Large Cell Lymphoma|Childhood Grade III Lymphomatoid Granulomatosis|Childhood Immunoblastic Large Cell Lymphoma|Childhood Nasal Type Extranodal NK/T-cell Lymphoma|Hepatosplenic T-cell Lymphoma|Intraocular Lymphoma|Noncutaneous Extranodal Lymphoma|Peripheral T-cell Lymphoma|Recurrent Childhood Acute Lymphoblastic Leukemia|Recurrent Childhood Anaplastic Large Cell Lymphoma|Recurrent Childhood Grade III Lymphomatoid Granulomatosis|Recurrent Childhood Large Cell Lymphoma|Recurrent Childhood Lymphoblastic Lymphoma|Recurrent Childhood Small Noncleaved Cell Lymphoma|Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma|Recurrent Mycosis Fungoides/Sezary Syndrome|Recurrent/Refractory Childhood Hodgkin Lymphoma|Refractory Chronic Lymphocytic Leukemia|Refractory Hairy Cell Leukemia|Small Intestine Lymphoma|T-cell Childhood Acute Lymphoblastic Leukemia|T-cell Large Granular Lymphocyte Leukemia|Unspecified Childhood Solid Tumor, Protocol Specific
Interventions: DRUG: oxaliplatin|DRUG: etoposide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GET-UP Trial: Impact of an Early Out-of-bed Paradigm in Postoperative Outcomes of Chronic Subdural Hematomas
Status: UNKNOWN
Conditions: Chronic Subdural Hematoma
Interventions: PROCEDURE: Early mobilization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fecal Microbiota Transplantation for Decompensated Cirrhosis
Status: UNKNOWN
Conditions: Decompensated Cirrhosis|Fecal Microbiota Transplantation
Interventions: BIOLOGICAL: FMT|OTHER: traditional treatments
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Delphinus SoftVue™ ROC Reader Study
Status: COMPLETED
Conditions: Breast Cancer Detection|Dense Breast Parenchyma|Benign Breast Findings|Normal Breast Screening|Abnormal Breast Screening
Interventions: DEVICE: Reading of Automated Breast Ultrasound in conjunction with Screening Mammography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Ifosfamide/Carboplatin/Etoposide/Rituxan Followed by Zevalin in Relapsed/Refractory Intermediate Grade B-Cell Lymphoma
Status: COMPLETED
Conditions: Non-Hodgkins Lymphoma
Interventions: DRUG: Ifosfamide|DRUG: Carboplatin|DRUG: Etoposide|DRUG: Rituximab|DRUG: 90Y Zevalin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: n-3 PUFA for Vascular Cognitive Aging
Status: UNKNOWN
Conditions: Age Related Cognitive Decline|Alzheimer's Disease|Vascular Dementia|Endothelial Dysfunction|Executive Dysfunction
Interventions: DRUG: Omega 3 PUFA|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Educational and Skills Training Program for Parents of Childhood Cancer Survivors Who Have Neurobehavioral Dysfunction
Status: COMPLETED
Conditions: Cancer Survivor|Cognitive/Functional Effects|Leukemia|Long-term Effects Secondary to Cancer Therapy in Children|Lymphoma|Psychosocial Effects of Cancer and Its Treatment
Interventions: OTHER: educational intervention|PROCEDURE: psychosocial assessment and care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose:
Clinical trial: Two Different Types of Luteal Phase Support in Natural Cycle Frozen Embryo Transfer and Its Effect on Pregnancy Rates
Status: RECRUITING
Conditions: Luteal Phase Support
Interventions: DRUG: GnRH agonist|DRUG: hCG|DRUG: Progesterone 100Mg Vag Tab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Reactogenicity Study of BoostrixTM (dTpa) and Boostrix-IPV (dTpa-IPV)
Status: COMPLETED
Conditions: Acellular Pertussis|Tetanus|Diphtheria
Interventions: BIOLOGICAL: Boostrix™ (dTpa)|BIOLOGICAL: GSK Biologicals' reduced-antigen-content combined diphtheria, tetanus, acellular pertussis and inactivated polio vaccine (dTpa-IPV; BoostrixTM)|BIOLOGICAL: Ditanrix™ Adult, TedivaxTM (Td)|BIOLOGICAL: Ditanrix™ Adult, TedivaxTM (Td)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: PSCA-CAR T Cells in Treating Patients With PSCA+ Metastatic Castration Resistant Prostate Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Castration-Resistant Prostate Carcinoma|Metastatic Prostate Carcinoma|Stage IV Prostate Cancer AJCC v8|Stage IVA Prostate Cancer AJCC v8|Stage IVB Prostate Cancer AJCC v8
Interventions: BIOLOGICAL: Autologous Anti-PSCA-CAR-4-1BB/TCRzeta-CD19t-expressing T-lymphocytes|DRUG: Cyclophosphamide|DRUG: Fludarabine|DRUG: Fludarabine Phosphate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Classical and Harp Music Practice on Premature Infants
Status: COMPLETED
Conditions: Music|Premature Infant|Cerebral Oxygenation|Comfort
Interventions: OTHER: Classical music|OTHER: Harp music
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Minimum Effective Volume for Selective Trunk Block
Status: COMPLETED
Conditions: Musculoskeletal Diseases or Conditions
Interventions: DRUG: a 1: 1 mixture of 2% lidocaine with 5ug/ml epinephrine and 0.5% levobupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Self Myofascial Release in Individuals With Piriformis Syndrome
Status: COMPLETED
Conditions: Piriformis Muscle Syndrome
Interventions: OTHER: Muscle Stretching|OTHER: Self Myofascial Release|OTHER: home exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Protein Intake Plus Neuromuscular Electrical Stimulation on Muscle Mass in Hospitalized Elderly
Status: RECRUITING
Conditions: Atrophy, Muscular
Interventions: DIETARY_SUPPLEMENT: Protein supplementation|DEVICE: Neuromuscular electrostimulation.|DIETARY_SUPPLEMENT: Placebo (isocaloric supplement)|DEVICE: Sham for neuromuscular electrostimulation.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Recombinant Epstein-Barr Virus (EBV) Vaccine in Patients With Nasopharyngeal Cancer Who Had Residual EBV DNA Load After Conventional Therapy
Status: COMPLETED
Conditions: Nasopharyngeal Cancer|Epstein-Barr Virus Infections
Interventions: BIOLOGICAL: Recombinant Epstein-Barr Virus (EBV) Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Intersection Between Loss of Control Eating and Obesity: The Role of Restriction and Food Reinforcement
Status: RECRUITING
Conditions: Pediatric Obesity|Nutrition Disorders|Binge Eating|Body Weight
Interventions: BEHAVIORAL: Restricted access task
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Assessment of the Effect of Vitamin C on Anemia in Patients With Continuous Ambulatory Peritoneal Dialysis
Status: COMPLETED
Conditions: Anemia
Interventions: DRUG: vitamin c|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Enteric-Coated Mycophenolate Sodium on Quality of Life in Patients With Gastrointestinal Symptoms Related to Mycophenolate Mofetil Therapy After Kidney Transplantation
Status: COMPLETED
Conditions: Renal Transplant
Interventions: DRUG: Enteric-Coated Mycophenolate Sodium (EC-MPS)|DRUG: Mycophenolate Mofetil (MMF)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of GSP 301 Nasal Spray in the Treatment of Seasonal Allergic Rhinitis (SAR)
Status: COMPLETED
Conditions: Seasonal Allergic Rhinitis (SAR)
Interventions: DRUG: GSP 301 NS|DRUG: GOM-NS|DRUG: GMM-2 NS|DRUG: GSP 301 placebo NS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Pharmacokinetic and Tolerance Study of Oral Ganciclovir in HIV-Infected Children With Asymptomatic Cytomegalovirus Infection and Low CD4 Cell Counts or Quiescent Cytomegalovirus Disease
Status: COMPLETED
Conditions: Cytomegalovirus Infections|HIV Infections
Interventions: DRUG: Ganciclovir
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multi-modal Characterisation of Gastroenteropancreatic Neuroendocrine Tumours (GEP-NETs) Treated With Targeted Radionuclide Therapy (TRT): Prospective Interventional Multicentre National Cohort
Status: RECRUITING
Conditions: Gastroenteropancreatic Neuroendocrine Tumor|Radiotherapy
Interventions: OTHER: Simultaneous 68Ga-DOTATOC PET-MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Clinical Trial to Evaluate the Efficacy and Safety of CKD-333 Tablet
Status: COMPLETED
Conditions: Hypertensive Patients With Dyslipidemia
Interventions: DRUG: CKD-330|DRUG: Placebo of CKD-330|DRUG: D086|DRUG: Placebo of D086|DRUG: D723|DRUG: Placebo of D723
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Thrombolysis in Myocardial Infarction (TIMI)
Status: COMPLETED
Conditions: Cardiovascular Diseases|Coronary Disease|Heart Diseases|Myocardial Infarction|Myocardial Ischemia
Interventions: DRUG: tissue plasminogen activator|PROCEDURE: angioplasty, transluminal, percutaneous coronary
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Cryotherapy and TENS on Low Back Pain
Status: UNKNOWN
Conditions: Low Back Pain, Mechanical
Interventions: DEVICE: Conventional TENS|DEVICE: Burst TENS|OTHER: Cryotherapy|DEVICE: Burst TENS + Cryotherapy|DEVICE: Conventional TENS + Cryotherapy|OTHER: Placebo TENS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Green Tea or Polyphenon E in Preventing Lung Cancer in Former Smokers With Chronic Obstructive Pulmonary Disease
Status: COMPLETED
Conditions: Lung Cancer Prevention
Interventions: DIETARY_SUPPLEMENT: green tea|DRUG: Polyphenon E|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Optimization of Deprescribing Antidepressants in Nursing Home Residents With Dementia
Status: COMPLETED
Conditions: Dementia|Deprescriptions|Antidepressive Agents|BPSD
Interventions: BEHAVIORAL: Teaching material|BEHAVIORAL: Pre-visit reflection tool|BEHAVIORAL: Dialogue tool|BEHAVIORAL: Educational session for GPs|BEHAVIORAL: Symptom assessment scale
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Neurotech Vital Compact Versus Itouch Sure Pelvic Floor Exerciser US
Status: COMPLETED
Conditions: Stress Urinary Incontinence
Interventions: DEVICE: Neurotech Vital Compact|DEVICE: itouch Sure Pelvic Floor Exerciser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Balloon Angioplasty vs. Cutting Balloon Angioplasty of Femoropopliteal Arteries- a Randomized Controlled Trial
Status: TERMINATED
Conditions: Peripheral Vascular Disease|Intermittent Claudication|Atherosclerosis|Angioplasty
Interventions: PROCEDURE: angioplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assess Veinplicity Venous Access Device Safety and Effectiveness
Status: COMPLETED
Conditions: Phlebotomy
Interventions: DEVICE: Stimulation-assisted venous access|OTHER: 20 guage cannula for IV, tourniquet optional
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety, Tolerability and Pharmacokinetics of Oral NX-13 in Healthy Adults Male and Female Volunteers
Status: COMPLETED
Conditions: Ulcerative Colitis
Interventions: DRUG: NX-13 250 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multi-parametric Ultrasound Versus Multi-parametric MRI for Prostate Cancer Detection
Status: NOT_YET_RECRUITING
Conditions: PROSTATE CANCER|Prostate Biopsy
Interventions: DIAGNOSTIC_TEST: Prostate imaging|PROCEDURE: Prostate biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of CT-388 in Otherwise Healthy Overweight and Obese Adults and Patients With Type 2 Diabetes Mellitus
Status: UNKNOWN
Conditions: Diabetes
Interventions: DRUG: CT-388|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Concurrent Chemotherapy and Radiotherapy With Nitroglycerin in Patients With Locally Advanced Non-Small Cell Lung Cancer
Status: UNKNOWN
Conditions: Locally Advanced Non Small-Cell Lung Canger
Interventions: DRUG: Transdermal nitroglycerin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Assess the Lanconone® (E-OA-07) Efficacy in Physical Activity-related Pain- LEAP Study
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: DIETARY_SUPPLEMENT: Lanconone|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics (PK)/Safety Study of Atorvastatin in Children With Kawasaki Disease and Coronary Artery Abnormalities
Status: COMPLETED
Conditions: Kawasaki Disease
Interventions: DRUG: Atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Detection of Azole Resistance Inducing Mutations on DNA Extracted Directly From Serum or Plasma of Immunocompromised Patients With an Invasive Aspergillus Infection Azole Resistance PCR Optimalization-study
Status: RECRUITING
Conditions: Invasive Aspergillosis
Interventions: DIAGNOSTIC_TEST: Aspergillus PCR
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Reduced-Intensity Regimen Before Donor Bone Marrow Transplant in Treating Patients With Myelodysplastic Syndromes
Status: COMPLETED
Conditions: Leukemia|Myelodysplastic Syndromes|Myelodysplastic/Myeloproliferative Neoplasms
Interventions: DRUG: Cyclosporine|DRUG: Methotrexate|DRUG: Photopheresis|DRUG: Mycofenolate mofetil|DRUG: Pentostatin|PROCEDURE: allogeneic bone marrow|PROCEDURE: peripheral blood stem cell|RADIATION: Total body irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Cavotricuspid Isthmus Ablation in Patients Without History of Typical Flutter During Ablation
Status: COMPLETED
Conditions: Paroxysmal Atrial Fibrillation
Interventions: PROCEDURE: cavotricuspid isthmus ablation|PROCEDURE: control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Billroth II or Roux-en-Y Reconstruction for GJ After PD: Randomized Controlled Trial (PAUDA TRIAL)
Status: COMPLETED
Conditions: Malignant Neoplasm of Head of Pancreas
Interventions: PROCEDURE: Pancreaticoduodenectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Computerized Exercise to Alter Stimulant Approach Responses
Status: UNKNOWN
Conditions: Amphetamine-Related Disorders|Cocaine-Related Disorders|Substance-Related Disorders
Interventions: BEHAVIORAL: Active CEASAR Intervention|BEHAVIORAL: Placebo CEASAR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Prevention of Pacemaker Lead Induced Tricuspid regurgitAtion by Transesophageal eCho guidEd Implantation Registry
Status: COMPLETED
Conditions: Tricuspid Valve Insufficiency|Pacemaker Complication|Echocardiography, Transesophageal
Interventions: PROCEDURE: Transesophageal guidance of lead implantation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: AZD2171 in Addition to Fulvestrant in Patients With Advanced Breast Cancer.
Status: COMPLETED
Conditions: Advanced Breast Cancer
Interventions: DRUG: AZD2171|DRUG: Fulvestrant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Dexmedetomidine on Recovery Profiles of Elderly Patients
Status: COMPLETED
Conditions: Elderly Patients|Anesthesia|Emergence From Anesthesia|Effects of Dexmedetomidine|Recovery From Anesthesia
Interventions: DRUG: Dexmedetomidine|DRUG: Sevoflurane|DRUG: Propofol and Remifentanil|DRUG: Normal saline|DRUG: Rocuronium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Role of Sympathetic Overactivity and Angiotensin II in PTSD and CV
Status: SUSPENDED
Conditions: Stress Disorders, Post-Traumatic
Interventions: PROCEDURE: Microneurography|BEHAVIORAL: Combat virtual reality video clip|PROCEDURE: Handgrip Exercise|PROCEDURE: Cold Pressor Test (CPT)|DRUG: Sodium Nitroprusside (SNP)|DRUG: Phenylephrine|DRUG: Losartan|DRUG: Atenolol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Severity of COVID-19 and Vitamin D Supplementation
Status: UNKNOWN
Conditions: COVID-19 Respiratory Infection
Interventions: DRUG: vitamin D
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Growth Hormone (GH) Treatment on Eating Regulation
Status: COMPLETED
Conditions: Short Stature
Interventions: BEHAVIORAL: growth hormone- Genotropin or NorditropinSimplex and nutritional intervention|BEHAVIORAL: growth hormone-Genotropin or NorditropinSimplex or "Biotropin"
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bortezomib and Low Dose Cytarabine in the Treatment of High-Risk Myelodysplastic Syndromes
Status: UNKNOWN
Conditions: Myelodysplastic Syndromes
Interventions: DRUG: Bortezomib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Shedding and Safety of Trivalent Influenza Virus Vaccine Live, Intranasal in Infants and Young Children
Status: COMPLETED
Conditions: Healthy
Interventions: BIOLOGICAL: Trivalent influenza virus vaccine live, intranasal
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Smoking Abstinence and Lapse Effects in Smokers With Schizophrenia and Controls
Status: COMPLETED
Conditions: Tobacco Use Disorder|Schizophrenia
Interventions: BEHAVIORAL: smoking abstinence
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: QUILT-2.018: Safety & Efficacy of FOLFIRI With AMG 479 or AMG 655 vs FOLFIRI Alone in KRAS-mutant Metastatic Colorectal Carcinoma
Status: COMPLETED
Conditions: Metastatic Colorectal Cancer
Interventions: OTHER: FOLFIRI|BIOLOGICAL: AMG 655|OTHER: Placebo|BIOLOGICAL: AMG 479
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness and Safety of Lactobacillus Rhamnosus Lcr35® in the Treatment of Recurrent Aphthous Stomatitis
Status: COMPLETED
Conditions: Aphthous Stomatitis
Interventions: DRUG: Bacilor|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: PET Imaging-guided Chemoradiotherapy in Esophageal Squamous Cell Carcinoma
Status: UNKNOWN
Conditions: Neoplasm, Esophageal|Squamous Cell Carcinoma
Interventions: DRUG: Paclitaxel|DRUG: Cisplatin|DRUG: Oxaliplatin|DRUG: 5-FU|DRUG: Leucovorin|RADIATION: Intensity-modulated radiotherapy|DEVICE: PET
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigation of Vasodilation and Intensity of Headache Triggered by Glucagon Like Peptide-1 in Humans
Status: UNKNOWN
Conditions: Headache, Migraine
Interventions: OTHER: GLP-1 peptide|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: The Effectiveness of Progressive Muscle Relaxation Technique in Reducing Cancer-related Pain
Status: COMPLETED
Conditions: Cancer-Related Pain
Interventions: OTHER: Progressive Muscle Relaxation (PMR) technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Ph 1, Single-Center, Safety, Tolerability & Pharmacokinetic Study of KX2 391 Ointment in Subj. w Actinic Keratosis
Status: COMPLETED
Conditions: Actinic Keratosis
Interventions: DRUG: KX2-391 Ointment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nurse-led Decision Counseling on Hepatocellular Carcinoma Screening
Status: COMPLETED
Conditions: Hepatitis B|Hepatocellular Carcinoma
Interventions: OTHER: Nurse-led decision counseling|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Endoscopic Variceal Ligation (EVL)+ Drugs Versus Endoscopic Variceal Ligation (EVL) Alone For Secondary Prophylaxis
Status: COMPLETED
Conditions: Portal Hypertension
Interventions: DRUG: EVL + Propranolol + Isosorbide 5 mononitrate|OTHER: EVL alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Misoprostol 400 µg Versus 200 µg for Cervical Ripening in 1st Trimester Miscarriage
Status: COMPLETED
Conditions: Miscarriage in First Trimester
Interventions: DRUG: Misoprostol 400mcg Tab|DRUG: Misoprostol 200mcg Tab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Chidamide With AZA in MRD Positive AML After Transplant
Status: RECRUITING
Conditions: AML, Adult|Minimal Residual Disease
Interventions: DRUG: chidamide and azacitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Nicotine on Chronic Pelvic Pain
Status: COMPLETED
Conditions: Pelvic Pain
Interventions: DRUG: Placebo|DRUG: Nicotine (5 mg)|DRUG: Nicotine (10 mg)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Robot Assisted Group Cognitive Training in Elderly Adults Without Cognitive Impairment
Status: COMPLETED
Conditions: Age-Related Cognitive Decline
Interventions: BEHAVIORAL: Robot assisted cognitive training|BEHAVIORAL: Conventional cognitive training group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effects of Mindfulness Training on Pain Regulation, Negative Affect, Attention, and Social Stress
Status: COMPLETED
Conditions: Focus on Pain Regulation Mechanisms|Social Stress Mechanisms|Basic Affective Mechanisms|Attention Mechanisms|Brain Mechanisms|Immune Mechanisms|Endocrine Mechanisms
Interventions: BEHAVIORAL: Mindfulness Based Stress Reduction (MBSR)|BEHAVIORAL: Health Enhancement Program (HEP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Chemotherapy With or Without Bevacizumab in Treating Patients With Stage IB, Stage II, or Stage IIIA Non-small Cell Lung Cancer That Was Removed By Surgery
Status: ACTIVE_NOT_RECRUITING
Conditions: Stage IB Lung Non-Small Cell Carcinoma AJCC v7|Stage IIA Lung Non-Small Cell Carcinoma AJCC v7|Stage IIB Lung Non-Small Cell Carcinoma AJCC v7|Stage IIIA Lung Non-Small Cell Cancer AJCC v7
Interventions: BIOLOGICAL: Bevacizumab|DRUG: Cisplatin|DRUG: Docetaxel|DRUG: Gemcitabine Hydrochloride|OTHER: Laboratory Biomarker Analysis|DRUG: Pemetrexed Disodium|OTHER: Questionnaire Administration|DRUG: Vinorelbine Tartrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transcutaneous Spinal Stimulation for Lower Limb Spasticity in Spinal Cord Injury
Status: RECRUITING
Conditions: Spinal Cord Injuries|Spasticity, Muscle
Interventions: OTHER: Electrical neuromodulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Cross-sectional Study on the Prevalence and Extraesophageal Symptoms of Gastroesophageal Reflux Disease(GERD) in Patients With Upper GI Symptoms, Visiting the Outpatient Departments of Peripheral Hospitals in Greece
Status: COMPLETED
Conditions: Gastroesophageal Reflux Disease
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Zandelisib (ME-401) in Subjects With Follicular Lymphoma or Marginal Zone Lymphoma After Failure of Two or More Prior Therapies (TIDAL)
Status: TERMINATED
Conditions: Follicular Lymphoma (FL)|Non Hodgkin Lymphoma|Marginal Zone Lymphoma
Interventions: DRUG: Zandelisib (ME-401)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Koebner's Phenomenon in Psoriasis and Lichen Planus
Status: NOT_YET_RECRUITING
Conditions: Kobner Phenomenon|Psoriasis|Lichen Planus
Interventions: PROCEDURE: Tape stripping
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: β-alanine Supplementation on Knee Extensor Contractile and Force Properties
Status: COMPLETED
Conditions: Muscle Function
Interventions: DIETARY_SUPPLEMENT: beta-alanine|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Entecavir Plus Tenofovir Combination in Subjects With Multi-drug Resistant Chronic Hepatitis B Virus Infection
Status: UNKNOWN
Conditions: Chronic Hepatitis B
Interventions: DRUG: Entecavir + Tenofovir (MDR group)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Psilocybin in Post-Treatment Lyme Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Post-Treatment Lyme Disease|Chronic Lyme Disease|Lyme Disease, Chronic
Interventions: DRUG: Psilocybin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acute Exposure to High Altitude on Symptoms
Status: COMPLETED
Conditions: Pulmonary Hypertension
Interventions: OTHER: Assessment at Low Altitude (470m above sea level)|OTHER: Exposure to High Altitude (2500m above sea level)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety and Pharmacokinetic Study of PF-06651600 in Japanese Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: PF-06651600|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Cannabis and Endocannabinoids on HIV Neuropathic Pain
Status: COMPLETED
Conditions: Cannabis|HIV Neuropathy|Pain Syndrome
Interventions: DRUG: Cannabis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neuro Linguistic Programming Pain Levels After Cesarean Delivery
Status: COMPLETED
Conditions: Nursing Caries|Pain, Postoperative
Interventions: BEHAVIORAL: NEURO-LINGUISTIC PROGRAMMING (NLP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE