pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Phase III, Randomized Trial: Lenalidomide vs Observation After Induction With Rituximab Followed by Cht and ASCT in MCL Adult Patients
Status: UNKNOWN
Conditions: MANTLE CELL LYMPHOMA
Interventions: DRUG: Lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness and Safety of IV Zemplar in Patients on Hemodialysis and With Secondary Hyperparathyroidism Using iPTH/100 as Initial Dose
Status: COMPLETED
Conditions: Secondary Hyperparathyroidism|Renal Insufficiency, Chronic|Parathyroid Hormone|Hemodialysis|Hypercalcemia
Interventions: DRUG: Zemplar (paricalcitol)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Efficacy and Safety of Switching From TDF to TAF in Adults With Chronic Hepatitis B Who Are Virologically Suppressed
Status: COMPLETED
Conditions: Chronic Hepatitis B
Interventions: DRUG: TAF|DRUG: TDF|DRUG: TAF Placebo|DRUG: TDF Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Selegiline for Smoking Cessation - 1
Status: COMPLETED
Conditions: Nicotine Dependence
Interventions: DRUG: Selegiline Transdermal Patch|DRUG: Placebo|BEHAVIORAL: Smoking Cessation Counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: LET Optimized IMPT in Treating Pediatric Patients With Ependymoma
Status: RECRUITING
Conditions: Anaplastic Ependymoma|Ependymoma
Interventions: RADIATION: Linear Energy Transfer-Optimized Intensity Modulated Proton Therapy|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nivolumab in Treating Patients With Localized Kidney Cancer Undergoing Nephrectomy
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Renal Cell Carcinoma|Sarcomatoid Renal Cell Carcinoma|Stage II Renal Cell Cancer AJCC v7|Stage III Renal Cell Cancer AJCC v7|Unclassified Renal Cell Carcinoma
Interventions: PROCEDURE: Nephrectomy|BIOLOGICAL: Nivolumab|OTHER: Patient Observation|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Exercise and Two Different Kinesiotape Applications in Patients With Sacroiliac Joint Dysfunction
Status: COMPLETED
Conditions: Sacroiliac Joint Dysfunction
Interventions: PROCEDURE: Home Exercise|PROCEDURE: Ligament Correction Kinesiotaping|PROCEDURE: Lymphatic Correction Kinesiotaping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of alpha1-antitrypsin to Treat Neuromyelitis Optica Relapses
Status: WITHDRAWN
Conditions: Neuromyelitis Optica
Interventions: DRUG: Alpha1-antitrypsin|DRUG: methylprednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mass Drug Administration of Ivermectin and Dihydroartemisinin-piperaquine as an Additional Intervention for Malaria Elimination
Status: COMPLETED
Conditions: Malaria
Interventions: DRUG: dihydroartemisinin-piperaquine (DP)|DRUG: ivermectin (IVM)|OTHER: standard malaria control interventions only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of Enzastaurin and Erlotinib in Participants With Solid Tumors and Lung Cancer
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer|Malignant Solid Tumor
Interventions: DRUG: enzastaurin|DRUG: erlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Analgesic Efficacy of Pulsed Radiofrequency in Non-cyclic Mastalgia
Status: COMPLETED
Conditions: Breast Fibroadenoma
Interventions: OTHER: pulsed radiofrequency of 2nd , 3rd and 4th thoracic dorsal root ganglia.|DRUG: Tamoxifen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of FRC Implant to Treat Skull Bone Defects
Status: UNKNOWN
Conditions: Cranial Bone Defect|Orbital Base Fracture
Interventions: DEVICE: FRC implant reconstruction|DEVICE: FRC implant reconstruction
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Domperidone on Completion Rate of Vedio Capsule Endoscopy
Status: COMPLETED
Conditions: Capsule Endoscopy|Pediatric Disorder
Interventions: DRUG: Domperidone|DIETARY_SUPPLEMENT: water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Clinical Study of Mitoxantrone Hydrochloride Liposome Combined With PD-1 Blockade in Recurrent or Metastatic NPC
Status: NOT_YET_RECRUITING
Conditions: Recurrent or Metastatic Nasopharyngeal Carcinoma
Interventions: DRUG: Mitoxantrone hydrochloride liposome injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Software Enhancements to the Respironics BiPAP Auto Servo Ventilation (AutoSV) Device
Status: COMPLETED
Conditions: Sleep Disordered Breathing|Sleep Apnea, Central
Interventions: DEVICE: Respironics BiPAP autoSV2|DEVICE: Respironics BiPAP autoSV3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Teta Burst Versus 10 Hz Repetitive Transcranial Magnetic Stimulation İn Neuropathic Pain: A Sham Controlled Comparison
Status: COMPLETED
Conditions: Neuropathic Pain
Interventions: DEVICE: Magstim Rapid2 Magnetic Stimulator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Autologous Bone Marrow Cell Transplantation in Persons With Acute Spinal Cord Injury- An Indian Pilot Study.
Status: COMPLETED
Conditions: Acute Spinal Cord Injury
Interventions: BIOLOGICAL: autologous bone marrow cell
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of CPC634 (CriPec® Docetaxel) in Platinum Resistant Ovarian Cancer
Status: COMPLETED
Conditions: Cancer|Ovarian Cancer
Interventions: DRUG: CPC634 (CriPec® docetaxel)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Microbial Evaluation of Denture Cleaning and Overnight Storage
Status: COMPLETED
Conditions: Denture Hygiene
Interventions: OTHER: denture brushing with water and soap|OTHER: ultrasonic denture cleaning|OTHER: cleansing tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Gemcitabine/Cisplatin/S-1(GCS) Combination Therapy for Patients With Advanced Biliary Tract Cancer
Status: COMPLETED
Conditions: Biliary Tract Cancer
Interventions: DRUG: S-1, Gemcitabine, Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Eradication of H-pylori in Pregnancy and Its Effect on Iron Replacement Therapy?
Status: UNKNOWN
Conditions: Pregnancy Complications|Anemia, Iron Deficiency|H Pylori Infection
Interventions: DRUG: triple attack therapy|DRUG: Ferrous(II)-glycine-sulphate complex 567.7 mg capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Compare the PK and Safety of Omalizumab (CT-P39, EU-approved Xolair, and US-licensed Xolair) in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: BIOLOGICAL: CT-P39|BIOLOGICAL: EU-approved Xolair|BIOLOGICAL: CT-P39|BIOLOGICAL: EU-approved Xolair|BIOLOGICAL: US-licensed Xolair
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Open-Label Phase 2 Efficacy Trial of Cancer Macrobeads in Patients With Treatment-Resistant Pancreatic/Colorectal Cancer
Status: COMPLETED
Conditions: Pancreatic Adenocarcinoma Non-resectable|Pancreatic Adenocarcinoma Metastatic|Colorectal Cancer Metastatic
Interventions: BIOLOGICAL: RENCA macrobeads
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: M-gCBT for Women With Provoked Localized Vulvodynia
Status: COMPLETED
Conditions: Provoked Localized Vulvodynia
Interventions: BEHAVIORAL: Mindfulness Based Group Cognitive BehaviorTherapy|BEHAVIORAL: Educational Seminars
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pivotal Evaluation of Abdominal Neuromuscular Electrical Stimulation (VentFree) for Weaning From Mechanical Ventilation
Status: ENROLLING_BY_INVITATION
Conditions: Respiration, Artificial|Ventilators, Mechanical
Interventions: DEVICE: Breath synchronized abdominal NMES|DEVICE: Sham breath synchronized abdominal NMES
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Iloperidone Virus Risperidone to Treat Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia|Iloperidone|Efficacy
Interventions: DRUG: iloperidone|DRUG: Risperidone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: HMBD-001 in Advanced HER3 Positive Solid Tumours
Status: RECRUITING
Conditions: Bladder Cancer|Triple Negative Breast Cancer|Castration-resistant Prostate Cancer|Cervical Cancer|RAS Wild Type Colorectal Cancer|Endometrial Cancer|Gastric Cancer|Hepatocellular Carcinoma (HCC)|Melanoma|Non-small Cell Lung Cancer (NSCLC)|Oesophageal Cancer|Ovarian Cancer|Pancreatic Cancer|Squamous Cell Cancer of the Head and Neck
Interventions: DRUG: HMBD-001
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intra and Inter Reliability of 30 Seconds Chair Stand Test as Self-test for Patients With Knee Osteoarthritis.
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: OTHER: Intra rater reliability|OTHER: Inter rater reliability
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: To Evaluate the Effectiveness(Immunogenicity) and Safety of 'GC1107' Administered Intramuscularly in Healthy Children
Status: COMPLETED
Conditions: Bacterial Infections
Interventions: BIOLOGICAL: GC1107|BIOLOGICAL: TD_PUR INJ / SK Td vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: mHealth Intervention to Reduce Maternal Postnatal Depression and Promote Family Health
Status: UNKNOWN
Conditions: Postnatal Depression|Quality of Life|Family Relations
Interventions: BEHAVIORAL: family-based mHealth Intervention|BEHAVIORAL: mother-only mHealth Intervention|OTHER: Health education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Tooth-Borne Versus Tooth-Bone-Borne Rapid Maxillary Expanders: A Stereophotogrammetric Evaluation of Soft Tissues
Status: COMPLETED
Conditions: Posterior Crossbite
Interventions: DEVICE: Rapid Maxillary Expansion Treatment with Tooth-borne RME appliance (Hyrax)|DEVICE: Rapid Maxillary Expansion Treatment with Hybrid hyrax RME appliance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sirolimus Therapy for Idiopathic and Lupus Membranous Nephropathy
Status: COMPLETED
Conditions: Membranous Glomerulonephritis|Lupus Membranous Nepropathy
Interventions: DRUG: Sirolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Intraoperative Intravenous Lidocaine on Postoperative Pain and Return of Bowel Function After Cesarean Sections
Status: COMPLETED
Conditions: Postoperative Pain|Postoperative Return of Bowel Function
Interventions: DRUG: Lidocaine IV|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Investigate the Pharmacokinetic Drug Interaction Between Udenafil and Bosentan After Oral Administration
Status: UNKNOWN
Conditions: Healthy Volunteers
Interventions: DRUG: Udenafil|DRUG: Bosentan|DRUG: Udenafil/Bosentan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Light Therapy for Moderate Traumatic Brain Injury
Status: COMPLETED
Conditions: Moderate Traumatic Brain Injury (TBI)
Interventions: DEVICE: Active LLLT helmet application|DEVICE: Non-active LLLT helmet application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Efficacy of Flywheel Inertial Resistance Training in the Architecture and Function of the Hamstring
Status: COMPLETED
Conditions: Hamstring Injury
Interventions: BEHAVIORAL: Exercises program for hamstring architecture and function
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Improving PRegnancy Outcomes With PReVEntive Therapy in Africa-2 (IMPROVE-2)
Status: COMPLETED
Conditions: Pregnancy; HIV; Malaria
Interventions: DRUG: Intermittent Preventive Therapy with Dihydroartemisinin-Piperaquine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Early vs Late Bladder Dissection During CS Hysterectomy in Patients With PAS With Bladder Invasion
Status: RECRUITING
Conditions: Placenta Accreta Spectrum|Cesarean Hysterectomy
Interventions: PROCEDURE: Late bladder dissection|PROCEDURE: early bladder dissection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy Plus EGFR Monoclonal Antibody in Patients With Liver Metastases From Colorectal Cancer With ctDNA Superselective Negative Genes
Status: NOT_YET_RECRUITING
Conditions: Liver Metastases of Colorectal Cancer
Interventions: DRUG: Capecitabine|DRUG: oxaliplatin|DRUG: Cetuximab|DRUG: Oxaliplatin|DRUG: Leucovorin|DRUG: 5-FU
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study on Shoulder Arthritis Treatment With Intra-articular Injections of Autologous Bone Marrow Aspirate.
Status: RECRUITING
Conditions: Shoulder Arthritis
Interventions: DEVICE: Marrow Cellution System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transpharyngeal Doppler Sonography for Cerebral Perfusion Monitoring
Status: COMPLETED
Conditions: Cerebral Perfusion
Interventions: DIAGNOSTIC_TEST: Transpharyngeal Doppler sonography (TPS)|DIAGNOSTIC_TEST: Conventional colour-coded Duplex sonography (CDS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Family-Focused, Stress-Reduction Program to Improve the Health Care of Urban Children With Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: BEHAVIORAL: Project ASPIRE Home-Based Family Intervention|BEHAVIORAL: Project ASPIRE Enhanced Treatment As Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Computer-Based Intervention for Medically Unexplained Physical Symptoms
Status: COMPLETED
Conditions: Fibromyalgia|Irritable Bowel Syndrome|Chronic Fatigue Syndrome
Interventions: BEHAVIORAL: Resilience Building Exercises|BEHAVIORAL: Journaling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study of Pomalidomide, Cyclophosphamide, Dexamethasone in Relapsed/Refractory Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma in Relapse|Multiple Myeloma, Refractory
Interventions: DRUG: Pomalidomide|DRUG: Cyclophosphamide|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Transdiagnostic Course for Common Mental Health Problems in Primary Care
Status: COMPLETED
Conditions: Depression|Anxiety
Interventions: BEHAVIORAL: Behavioral activation, evidence-based sleep strategies including sleep restriction, exposure-based strategies, promotion of physical activity and recuperating activities, psychoeducational material
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Symbiot III: A Prospective Randomized Trial Evaluating the Symbiot Covered Stent System in Saphenous Vein Grafts
Status: COMPLETED
Conditions: Symptomatic Ischemic Saphenous Vein Graft Disease
Interventions: DEVICE: Covered Stent System|DEVICE: Bare metal stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Olopatadine HCl Ophthalmic Solution for the Treatment of Allergic Conjunctivitis in Japan
Status: COMPLETED
Conditions: Allergic Conjunctivitis
Interventions: DRUG: Olopatadine HCl ophthalmic solution, 0.1%|DRUG: Epinastine HCl ophthalmic solution, 0.05%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Testing of TAK228 (MLN0128, Sapanisertib) Plus Docetaxel to the Usual Standard of Care for Advanced Squamous Cell Lung Cancer (A Lung-MAP Treatment Trial)
Status: WITHDRAWN
Conditions: Lung Squamous Cell Carcinoma|Recurrent Lung Carcinoma|Stage IV Lung Cancer AJCC v8|Stage IVA Lung Cancer AJCC v8|Stage IVB Lung Cancer AJCC v8
Interventions: DRUG: Dexamethasone|DRUG: Docetaxel|BIOLOGICAL: Ramucirumab|DRUG: Sapanisertib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Structural and Molecular Neuroplasticity in Migraine
Status: COMPLETED
Conditions: Migraine
Interventions: PROCEDURE: Pet Scan|PROCEDURE: MRI scan|PROCEDURE: Quantitative Sensory Testing (QST)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Oblimersen and Interferon Alfa in Treating Patients With Metastatic Renal Cell Cancer
Status: COMPLETED
Conditions: Recurrent Renal Cell Cancer|Stage IV Renal Cell Cancer
Interventions: BIOLOGICAL: recombinant interferon alfa|BIOLOGICAL: oblimersen sodium|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Does a Clinical Support System for Parenteral Nutrition (PN) Facilitate the Judgement on Choosing the Most Effective Commercial Solution Per Patient (and Modify it, if Necessary)?
Status: COMPLETED
Conditions: Clinical Decision Support System
Interventions: OTHER: CDSS Canceling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Pericapsular Nerve Group (PENG) Block Combined With Periarticular Multimodal Drug Injection (PMDI) Versus Isolated PMDI for Pain Management After Total Hip Arthroplasty: a Randomized Controlled Trial
Status: UNKNOWN
Conditions: Total Hip Arthroplasty, Postoperative Pain
Interventions: PROCEDURE: Pericapsular nerve group(PENG) block combined with periarticular multimodal drug injection (PMDI)|PROCEDURE: isolated periarticular multimodal drug injection (PMDI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Acute Effects of Foam Rolling and Proprioceptive Neuromuscular Facilitation Stretching
Status: RECRUITING
Conditions: Athletes
Interventions: OTHER: Foam Rolling|OTHER: Proprioceptive Neuromuscular Facilitation Stretching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: EPOCH: Eribulin and Pembrolizumab in Ovarian/Uterine Carcinosarcoma
Status: RECRUITING
Conditions: Ovarian Carcinosarcoma|Uterine Carcinosarcoma
Interventions: DRUG: Eribulin Mesylate|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PD-1 Antibody Expressing mesoCAR-T Cells for Mesothelin Positive Advanced Solid Tumor
Status: UNKNOWN
Conditions: Advanced Solid Tumor
Interventions: BIOLOGICAL: PD-1 antibody expressing mesoCAR-T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Total Intravenous Anesthesia for Rigid Bronchoscopy Using Remimazolam
Status: NOT_YET_RECRUITING
Conditions: Respiratory Disease|Tracheal Stenosis|Endobronchial Mass
Interventions: DRUG: Remimazolam besylate|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Fecal Microbiota Transplantation for Chronic Functional Constipation
Status: UNKNOWN
Conditions: Chronic Functional Constipation|Intestinal Bacteria Flora Disturbance|Fecal Microbiota Transplantation
Interventions: OTHER: Fecal Microbiota Transplantation|OTHER: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Compare Oral Itraconazole and Standard Care Versus Standard Care Alone in Patients With Non-cystic Fibrosis Related Bronchiectasis With Chronic Aspergillus Infection in Reducing Bronchiectasis Exacerbations
Status: RECRUITING
Conditions: Bronchiectasis|Bronchiectasis Adult
Interventions: DRUG: Itraconazole 65 MG|OTHER: Standard care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of Integrated Treatment Versus Standard Treatment in First Episode Psychosis
Status: UNKNOWN
Conditions: Psychotic Disorders|Schizophreniform Disorders|Schizoaffective Disorder|Psychosis, Brief Reactive|Schizophrenia, Borderline
Interventions: BEHAVIORAL: Integrated treatment, family involvement|BEHAVIORAL: Social skills training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of DHA for the Treatment of PSC
Status: COMPLETED
Conditions: Primary Sclerosing Cholangitis|Colitis
Interventions: DRUG: Docosahexaenoic Acid (DHA)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Baricitinib (LY3009104) in Healthy Chinese Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Baricitinib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Drug-drug Interaction Study Between Edaravone and 2-Aminoethanesulfonic Acid in Compound Edaravone Injection
Status: COMPLETED
Conditions: Drug-drug Interaction
Interventions: DRUG: Compound Edaravone Injection|DRUG: Edaravone Injection|DRUG: 2-Aminoethanesulfonic Acid Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Telemedicine-Delivered Unified Protocol for Cognitive Behavioral Therapy for Anxiety and Depression
Status: RECRUITING
Conditions: Diabetes|Type 1 Diabetes
Interventions: BEHAVIORAL: Unified protocol for cognitive behavioral therapy (UP-CBT)|DEVICE: Continuous Glucose Monitoring (CGM)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of EG12014 Compared With Herceptin in Subjects With HER2 Positive Early Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: EG12014|DRUG: Herceptin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Medication Maintenance Therapy in Community Pharmacy Settings
Status: UNKNOWN
Conditions: Opioid-use Disorder
Interventions: DRUG: buprenorphine/naloxone oral product|DRUG: injectable naltrexone|OTHER: Pharmacy maintenance addiction care|DRUG: oral naltrexone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Antiviral Effect, Safety and Tolerability of GSK3810109A in Viremic Human Immunodeficiency Virus (HIV)-1 Infected Adults
Status: COMPLETED
Conditions: HIV Infections
Interventions: BIOLOGICAL: GSK3810109A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Motivational Interview Teqhnique in Pregnant Women Who Are Hesitant in Childhood Vaccines
Status: NOT_YET_RECRUITING
Conditions: Vaccine Refusal|Pregnancy Related|Motivation
Interventions: BEHAVIORAL: Motivational Interwiev
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Normative Metrics of High-Resolution Anorectal Manometry With the Use of Solid-State Catheter in a Healthy Russian Cohort
Status: UNKNOWN
Conditions: Healthy Subjects
Interventions: DIAGNOSTIC_TEST: High-Resolution anorectal manometry with the use of solid-state catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Clinical Trial Assessing the Efficacy of Capsaicin Patch (Qutenza®) in Cancer Patients With Neuropathic Pain
Status: COMPLETED
Conditions: Neuropathic Pain
Interventions: DRUG: Qutenza
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EUS-guided Biliary Drainage Versus Percutanenous Transhepatic Biliary Darinage for Malignant Biliary Obstruction After Failed ERCP
Status: COMPLETED
Conditions: Cholestasis, Extrahepatic
Interventions: DEVICE: EUS-BD|DEVICE: PTBD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study to Determine the Maximum Tolerated Dose of the PARP Inhibitor CEP-9722 in Participants With Solid Tumors
Status: TERMINATED
Conditions: Solid Tumors
Interventions: DRUG: CEP-9722
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigating Fear Of Recurrence as a Modifiable Mechanism of Behavior Change
Status: COMPLETED
Conditions: Acute Coronary Syndrome|Fear|Medication Adherence
Interventions: BEHAVIORAL: Cognitive Bias Modification Training|BEHAVIORAL: Attention Control Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Pilot Study of an Online HIV Stigma Training for Nursing Students in Iran
Status: RECRUITING
Conditions: Stigma, Social|HIV Infections
Interventions: BEHAVIORAL: The online HIV-related stigma training|BEHAVIORAL: The online HIV epidemiology training with no specific content on stigma
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: SY007 in Patients With Acute Ischemic Stroke
Status: SUSPENDED
Conditions: Acute Ischemic Stroke
Interventions: DRUG: SY-007/ Placebo 15mg|DRUG: SY-007/ Placebo 30mg|DRUG: SY-007/ Placebo 60mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Chronic Bacterial Prostatitis
Status: COMPLETED
Conditions: Chronic Bacterial Prostatitis
Interventions: DRUG: Third generation fluoroquinolone|DIETARY_SUPPLEMENT: Nutritional supplement + third generation fluoroquinolone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: AFR10 - Combination Therapy of Imatinib Mesylate (IM) + Alpha-2A Interferon for Chronic Phase CML Patients Resistant or Refractory to IM Used as Single Therapy for at Least One Year
Status: UNKNOWN
Conditions: Chronic Myeloid Leukemia
Interventions: DRUG: Imatinib mesylate 600mg/day|DRUG: Peg-Interféron at 90 microg/week
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Epileptic Seizure in Epilepsy Patients After SARS-CoV-2 Vaccination
Status: COMPLETED
Conditions: Epileptic Seizures Related to Drugs|SARS-CoV-2 Acute Respiratory Disease|Vaccine Adverse Reaction
Interventions: BIOLOGICAL: inactive SARS-Cov-2 vaccine
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of Human Efficacy for Skin Moisturization and Wrinkle Improvement
Status: COMPLETED
Conditions: Dry Skin
Interventions: COMBINATION_PRODUCT: Hs-hWE cream|COMBINATION_PRODUCT: Placebo cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Interest of a 30 Minutes' Intermittent Work Exercise Test in Patients With Chronic Obstructive Pulmonary Disease: Cardiac and Pulmonary Functions
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: PROCEDURE: EFR
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Vaccine Therapy With or Without Imiquimod in Treating Patients Who Have Undergone Surgery for Stage II, Stage III, or Stage IV Melanoma
Status: COMPLETED
Conditions: Melanoma (Skin)
Interventions: BIOLOGICAL: incomplete Freund's adjuvant|BIOLOGICAL: multi-epitope melanoma peptide vaccine|BIOLOGICAL: sargramostim|BIOLOGICAL: tetanus toxoid helper peptide|DRUG: dimethyl sulfoxide|DRUG: imiquimod|PROCEDURE: adjuvant therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Celecoxib on Postoperative Analgesia and Disease Severity in AERD Patients With CRS
Status: RECRUITING
Conditions: Chronic Rhinosinusitis With Nasal Polyps|Aspirin-exacerbated Respiratory Disease
Interventions: DRUG: Celecoxib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Sugammadex Administered at 5 Minutes After Administration of 1.2 mg/kg Esmeron® (19.4.205)(P05942)
Status: COMPLETED
Conditions: Anesthesia, General
Interventions: DRUG: sugammadex|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Autologous Bone Marrow Mononuclear Cell Transplantation in Treating Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: OTHER: BMMCT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Define the Role of GLP-1 for Improving Glucose Homeostasis in Humans Following Gastric Bypass Surgery
Status: COMPLETED
Conditions: Bypass, Gastric|Roux-en-Y Gastric Bypass|Vertical Sleeve Gastrectomy|Gastric Banding|Bariatric Surgery
Interventions: DRUG: Placebo|DRUG: Lo-Xenin|DRUG: Hi-Xenin|DRUG: Extra Hi-Xenin
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Early Multimodal Neuromonitoring For Spontaneous Intracerebral Hemorrhage (ICH)
Status: COMPLETED
Conditions: Intracerebral Hemorrhage|Critically Ill|Intracranial Pressure|Cerebral Perfusion Pressure|Prognostic
Interventions: DIAGNOSTIC_TEST: Multimodal Neuromonitoring
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Transfusion Strategies for Pediatric Liver Transplantation
Status: UNKNOWN
Conditions: Pediatric Patients Who Need Liver Transplantation
Interventions: OTHER: restrictive transfusion|OTHER: liberal transfusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transcutaneous Electrical Nerve Stimulation and Interferential Currents in Chronic Low Back Pain
Status: COMPLETED
Conditions: Chronic Low Back Pain
Interventions: OTHER: TENS|OTHER: Interferential currents
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Acuvue Oasys 1-Day Contact Lenses in New Wearers
Status: COMPLETED
Conditions: Visual Acuity
Interventions: DEVICE: ACUVUE OASYS® 1-DAY with HydraLuxe™ TECHNOLOGY (AO1D)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Breast Pump Suction Patterns
Status: RECRUITING
Conditions: Insufficient Breast Milk Syndrome
Interventions: BEHAVIORAL: Breast Pump suction pattern
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Hypotaurine Supplementation Benefits in Cryopreservation
Status: COMPLETED
Conditions: Cryopreservation|Human Spermatozoa Parameters|Hypotaurine Supplementation|Spermatozoa DNA Alterations
Interventions: OTHER: Hypotaurine : antioxidant and osmoregulator
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Efficacy of Aescin in Combination With MPFF in the Early Control of Bleeding From Acute Internal Hemorrhoids, A Randomized Controlled Trial
Status: NOT_YET_RECRUITING
Conditions: Anorectal Disorder
Interventions: DRUG: Aescin in Horse Chestnut|DRUG: Flavonoid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability of Ertapenem Sodium in the Treatment of Complicated Urinary Tract Infections (0826-055)
Status: COMPLETED
Conditions: Urinary Tract Infection
Interventions: DRUG: ertapenem sodium (MK0826)|DRUG: Comparator: ceftriaxone sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: TBTC Study 30: Safety and Tolerability of Low Dose Linezolid in MDR TB
Status: COMPLETED
Conditions: Multi-drug Resistant Tuberculosis|Extensively Drug Resistant Tuberculosis
Interventions: DRUG: Linezolid|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Subcision and Suction on Acne Scars
Status: ACTIVE_NOT_RECRUITING
Conditions: Acne Scars
Interventions: PROCEDURE: Suction|PROCEDURE: Subcision
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bevacizumab With or Without Fosbretabulin Tromethamine in Treating Patients With Recurrent or Persistent Ovarian Epithelial, Fallopian Tube, or Peritoneal Cavity Cancer
Status: COMPLETED
Conditions: Recurrent Fallopian Tube Carcinoma|Recurrent Ovarian Carcinoma|Recurrent Primary Peritoneal Carcinoma
Interventions: BIOLOGICAL: Bevacizumab|DRUG: Fosbretabulin Tromethamine|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of a Digestive Enzyme Blend
Status: UNKNOWN
Conditions: Digestive Health|Indigestion|Protein Digestion|Carbohydrate Digestion|Fat Digestion|Satiety
Interventions: DIETARY_SUPPLEMENT: Digestive enzyme blend|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety and Efficacy of Non-ablative Er:YAG Laser Therapy for the Treatment of Pelvic Organ Prolapse and Coexisting Stress Urinary Incontinence: A Retrospective Case Series.
Status: COMPLETED
Conditions: Cystocele|Pelvic Organ Prolapse|Stress Urinary Incontinence
Interventions: DEVICE: Fotona ProlapLase
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Activated Recombinant Human Factor VII in Patients With Dengue Haemorrhagic Fever
Status: COMPLETED
Conditions: Acquired Bleeding Disorder|Dengue Haemorrhagic Fever
Interventions: DRUG: activated recombinant human factor VII|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Vitamin D, Diet and Activity Study
Status: COMPLETED
Conditions: Breast Cancer|Obesity|Hypovitaminosis D
Interventions: DIETARY_SUPPLEMENT: Vitamin D|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose:
Clinical trial: Effect of Pioglitazone on Insulin Resistance and Atherosclerosis in Renal Allograft Recipients Without Diabetes
Status: COMPLETED
Conditions: Kidney Transplantation|Insulin Resistance|Atherosclerosis
Interventions: DRUG: Pioglitazone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The PCSK9i Inhibitor Evolocumab - a Surgical Trial of Pharamcodynamics and Kinetics Evaluation
Status: COMPLETED
Conditions: Malignant Glioma|Glioblastoma
Interventions: DRUG: Evolocumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Evaluate the Safety and Immunogenicity of Seasonal Influenza Vaccine and an Adenovirus Serotype 26- Based Vaccine Encoding for the Respiratory Syncytial Virus Pre-fusion F Protein (Ad26.RSV.preF), With and Without Co-administration, in Adults Aged 60 Years and Older in Stable Health
Status: COMPLETED
Conditions: Healthy
Interventions: BIOLOGICAL: Ad26.RSV.preF|BIOLOGICAL: Fluarix|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Intravenous High Dose NAC and Sodium Bicarbonate for the Prevention of Contrast-induced Acute Injury
Status: COMPLETED
Conditions: Acute Renal Failure
Interventions: DRUG: Sodium bicarbonate plus saline|DRUG: Intravenous NAC plus saline|DRUG: NAC plus sodium bicarbonate plus saline|DRUG: Saline|DRUG: NAC plus saline|DRUG: NAC plus sodium bicarbonate plus saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Efficacy and Safety of QLF31907 Combination Therapy in Patients With Advanced Malignant Tumors
Status: NOT_YET_RECRUITING
Conditions: Advanced Malignant Neoplasm
Interventions: DRUG: QLF31907|DRUG: Irinotecan|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Vibostolimab Alone and in Combination With Pembrolizumab in Advanced Solid Tumors (MK-7684-001) ( KEYVIBE-001)
Status: COMPLETED
Conditions: Neoplasms
Interventions: BIOLOGICAL: vibostolimab|BIOLOGICAL: pembrolizumab|DRUG: pemetrexed|DRUG: carboplatin|BIOLOGICAL: pembrolizumab/vibostolimab coformulation|DRUG: cisplatin|DRUG: etoposide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Predictive Factors for Ruptures of Meije Duo ™ Size 1 and 2 Femoral Stems in Hip Replacement Surgery
Status: COMPLETED
Conditions: Hip Arthropathy Associated With Other Conditions
Interventions: OTHER: Radiographs
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: SEEG Guided RF-TC v.s. ATL for mTLE With HS
Status: COMPLETED
Conditions: Epilepsy, Temporal Lobe
Interventions: PROCEDURE: SEEG guided RF-TC|PROCEDURE: Anterior temporal lobectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: HIV/STI Prevention Among Black Adolescents With Mental Illnesses (Project GOLD)
Status: COMPLETED
Conditions: HIV|STI|Emotional Disturbances|Mental Disorder
Interventions: BEHAVIORAL: HIV/STI Prevention Intervention|BEHAVIORAL: General Health Control Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Combined Electromagnetic Field and a Plantar Resistance Exercise With Venous Leg Ulcer
Status: UNKNOWN
Conditions: Venous Leg Ulcer
Interventions: COMBINATION_PRODUCT: electromagnetic field and a plantar resistance exercise|DEVICE: Pulsed electromagnetic field|OTHER: usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Biomechanical and Morphological Characterization of PTTD
Status: RECRUITING
Conditions: Posterior Tibial Tendon Dysfunction
Interventions: DIAGNOSTIC_TEST: Radiography|DIAGNOSTIC_TEST: Ultrasound|DIAGNOSTIC_TEST: MRI|DIAGNOSTIC_TEST: CT-scan|DIAGNOSTIC_TEST: Gait analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety, Tolerability and Immunogenicity of Three Doses of Novartis Meningococcal B Vaccine When Administered to Healthy At-risk Adults
Status: COMPLETED
Conditions: Meningococcal Disease
Interventions: BIOLOGICAL: Men ACWY CRM|BIOLOGICAL: 4CMenB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Fixed Combination Citicoline Homotaurine and Pyrroloquinoline Quinone on Pattern-electroretinogram in Glaucoma
Status: RECRUITING
Conditions: Glaucoma|Neuroprotection
Interventions: COMBINATION_PRODUCT: Citicoline 500 mg plus Homotaurine 50 mg plus Pyrroloquinoline quinone (Neuprozin Mito® )
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Short-term L-citrulline Supplementation on Blood Pressure and Arterial Stiffness
Status: COMPLETED
Conditions: Blood Pressure
Interventions: DIETARY_SUPPLEMENT: L-Citrulline|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety Eval of Guanfacine Hydrochloride in Combination With Psychostimulants in Adults (18-65).
Status: COMPLETED
Conditions: Adult Attention-Deficit Hyperactivity Disorder
Interventions: DRUG: Guanfacine Hydrocholride|DRUG: Guanfacine Hydrocholride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Prolonged DAPT After Lower Extremity Percutaneous Transluminal Angioplasty (PTA) in Patients With LE-PAD
Status: UNKNOWN
Conditions: Peripheral Artery Disease
Interventions: DRUG: Short DAPT|DRUG: Long DAPT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety, and Tolerability, and Efficacy of Seladelpar in Patients With PSC
Status: COMPLETED
Conditions: Primary Sclerosing Cholangitis
Interventions: DRUG: Seladelpar|DRUG: Placebo to match Seladelpar
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT