pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Erythropoietic Protoporphyrias: Studies of the Natural History, Genotype-Phenotype Correlations, and Psychosocial Impact
Status: COMPLETED
Conditions: Erythropoietic Protoporphyria|EPP|X-Linked Protoporphyria|XLP|XLPP|X-Linked Dominant Erythropoietic Protoporphyria|XLEPP|XLDP
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of Multiple Dose Regimens of MT-3724 With Lenalidomide for the Treatment of Participants With Relapsed/Refractory B-Cell Non-Hodgkin's Lymphoma (MT-3724_NHL_003)
Status: TERMINATED
Conditions: Non-hodgkin Lymphoma
Interventions: DRUG: MT-3724
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Music Therapy in Obsessive Compulsive Disorder
Status: COMPLETED
Conditions: Obsessive-Compulsive Disorder|Anxiety|Depression
Interventions: DRUG: Selective serotonin re-uptake inhibitor|BEHAVIORAL: Cognitive Behavioral Therapy|OTHER: Music therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Effect of Single and Multiple Doses Org 50081 and a Single Dose of Zopiclone on Next-day Driving Ability and Psychomotor Performance in Healthy Volunteers. (P05794) (COMPLETED)
Status: COMPLETED
Conditions: Sleep Initiation and Maintenance Disorders|Mental Disorders
Interventions: DRUG: Org 50081|DRUG: Org 50081|DRUG: Placebo|DRUG: zopiclone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Two Distraction Strategies in Reducing Preoperative Anxiety in Children
Status: COMPLETED
Conditions: Attention-Distributing Strategies|Preoperative Anxiety
Interventions: OTHER: Music Intervention|OTHER: The animation intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Clinical Trial for Examining the Therapeutic Equivalence Between Fluticasone Propionate 100 mcg/Blister Oral Inhalation Powder/Respirent Pharmaceuticals vs. FLOVENT DISKUS® 100mcg/Blister Oral Inhalation Powder/GSK in Patients With Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Fluticasone propionate 100 mcg/blister oral inhalation powder/Respirent Pharmaceuticals|DRUG: FLOVENT DISKUS® 100 mcg/blister oral inhalation powder/GSK|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: BIOTIPRA: BIOmarker-guided Treatment Decisions In Psoriatic and Rheumatoid Arthritis
Status: RECRUITING
Conditions: Arthritis, Rheumatoid
Interventions: DIAGNOSTIC_TEST: Tests for drug levels and anti-drug antibodies
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pain Sensitivity During Puberty
Status: ACTIVE_NOT_RECRUITING
Conditions: Pain
Interventions: DEVICE: Thermal Sensory Analyzer|DEVICE: Pressure Stimuli|DEVICE: Mechanical Stimuli|BEHAVIORAL: Pain Ratings|BEHAVIORAL: Thermal pain thresholds|BEHAVIORAL: Pressure pain thresholds (PPT)|BEHAVIORAL: Mechanical temporal summation|BEHAVIORAL: Conditioned pain modulation (CPM) efficiency|BEHAVIORAL: Offset analgesia efficiency|BEHAVIORAL: Cold pain tolerance
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Bendamustine Plus Rituximab (BR) for Relapsed or Progressive Marginal Zone B-cell Lymphoma (MZBCL)
Status: COMPLETED
Conditions: Marginal Zone B-cell Lymphoma
Interventions: DRUG: bendamustine plus rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Safety and Efficacy of AlphaWave® L-Theanine on Adults Who Experience Moderate Stress on a Regular Basis
Status: COMPLETED
Conditions: Stress
Interventions: DIETARY_SUPPLEMENT: AlphaWave® L-Theanine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Intervention Study to Investigate the Effect of B-vitamin Supplementation for 2-years on Bone Health
Status: COMPLETED
Conditions: Bone Health
Interventions: DIETARY_SUPPLEMENT: B-vitamin supplementation on bone health|DIETARY_SUPPLEMENT: Control group; Vitamin D, a daily capsule containing 10 µg/day vitamin D
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Resistance Swallowing Training in Patients With Tracheotomy
Status: NOT_YET_RECRUITING
Conditions: Swallowing Training on Muscle Strength
Interventions: OTHER: pure effortful swallowing|OTHER: progressive resistance swallowing training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The O'Neil Long Acting Naltrexone Implant (OLANI) Pharmacokinetic (PK)/Safety Study in Healthy Volunteers
Status: COMPLETED
Conditions: Opioid Use Disorder
Interventions: DRUG: naltrexone implant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Novel Wound Retractor Combining Continuous Irrigation and Barrier Protection Reduces Incisional Contamination and Surgical Site Infection in Colorectal Surgery
Status: ACTIVE_NOT_RECRUITING
Conditions: Colorectal Surgery
Interventions: DEVICE: CleanCision Wound Retraction and Protection System|DEVICE: Alexis O Wound Protector
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Fluorescence Imaging in Sentinel Lymph Node Biopsy for Breast Cancer and Melanoma
Status: COMPLETED
Conditions: Breast Cancer|Cancer of Breast|Cancer of the Breast|Melanoma|Malignant Melanoma
Interventions: PROCEDURE: Sentinel lymph node biopsy|DEVICE: Goggle-based device with light-emitting diodes (LED)|DRUG: Indocynanine Green
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Pharmacological Treatment of Comorbid Alcohol and Marijuana Withdrawal and Dependence
Status: COMPLETED
Conditions: Cannabis Dependence|Alcohol Dependence|Cannabis Use Disorder|Alcohol Use Disorder
Interventions: DRUG: aprepitant|DRUG: Placebo|BEHAVIORAL: Manual-guided behavioral counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Effectiveness of Topotecan HCl to Treat HIV-Infected Patients With AIDS-Related Progressive Multifocal Leukoencephalopathy (PML)
Status: COMPLETED
Conditions: HIV Infections|Leukoencephalopathy, Progressive Multifocal
Interventions: DRUG: Topotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Photobiomodulation Therapy (PBMT) in Patients With Low Back Pain (LBP)
Status: UNKNOWN
Conditions: Low Back Pain
Interventions: DEVICE: Active PBMT|DEVICE: Placebo PBMT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Verbal Memory Training Using Virtual Reality in Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder
Interventions: BEHAVIORAL: Cognitive Intervention|BEHAVIORAL: Active Control Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Low Dose IL-2, Hematopoietic Stem Cell Transplantation, IL2 for GVHD
Status: COMPLETED
Conditions: Acute Lymphoblastic Leukemia|ALL|Acute Myelogenous Leukemia|AML|Chronic Myelogenous Leukemia|Myelodysplastic Syndrome|Myeloproliferative Disorder|Hodgkin Lymphoma|Non-Hodgkin Lymphoma|Non-malignant Diseases Requiring Allogeneic HSCT
Interventions: BIOLOGICAL: IL-2
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Total Knee Arthroplasties With Oxidized Zirconium and Cobalt Chromium Femoral Components
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DEVICE: Zirconium (Zirconium Genesis II)|DEVICE: Cobalt-Chrome (Cobalt Chrome Genesis II)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ketoconazole With or Without Alendronate Sodium in Treating Patients With Metastatic Prostate Cancer
Status: TERMINATED
Conditions: Stage IV Prostate Cancer|Bone Metastases|Adenocarcinoma of the Prostate|Recurrent Prostate Cancer
Interventions: DRUG: alendronate sodium|DRUG: ketoconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: O2 Consumption and Heart Rate Response to Battle Rope Exercise Protocol Versus UE Arm Bike Test in Adults With SCI
Status: UNKNOWN
Conditions: Spinal Cord Injury at T2 and Below
Interventions: DEVICE: Seated Battle Ropes Protocol|DEVICE: Seated Upper Extremity Arm Bike
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rituximab, Gemcitabine and Oxaliplatin (R-GEMOX) for Refractory/Relapsed B-cell Lymphoma
Status: COMPLETED
Conditions: Diffuse Large Cell Lymphoma
Interventions: DRUG: Gemcitabine-Oxaliplatin plus Rituximab (R-GEMOX)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Pegylated rhG-CSF as Support to Advanced Non-Small-Cell Lung Cancer (NSCLC) Patients Receiving Chemotherapy Receiving Chemotherapy
Status: UNKNOWN
Conditions: NSCLC|Neutropenia|Febrile Neutropenia
Interventions: DRUG: Pegylated rhG-CSF: 100µg/kg|DRUG: Pegylated rhG-CSF: 6mg|DRUG: placebo and rhG-CSF 5ug/kg/d
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Paracetamol,Pregabalin and Dexamethasone on Pain and Opioid Requirements in Postoperative Patients
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: DRUG: Pregabalin; Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Stepped-Care Cognitive-Behavioral Treatment for Youth With ASD and Anxiety
Status: COMPLETED
Conditions: Cognitive Behavioral Therapy|Autism Spectrum Disorder|Anxiety Disorders|Obsessive-Compulsive Disorder|Social Anxiety Disorder|Generalized Anxiety Disorder|Specific Phobia
Interventions: BEHAVIORAL: Stepped Care CBT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radiation, Chemotherapy, Vaccine and Anti-MART-1 and Anti-gp100 Cells for Patients With Metastatic Melanoma
Status: COMPLETED
Conditions: Melanoma|Skin Cancer
Interventions: DRUG: MART-1: 26-35(27L) Peptide|DRUG: Montanide ISA 51 VG|DRUG: gp100:154-162 Peptide|PROCEDURE: Radiation|DRUG: Aldesleukin|DRUG: Fludarabine|DRUG: Cyclophosphamide|GENETIC: Anti-gp 100:154 TCR PBL|GENETIC: Anti-MART-1 F5 TCR PBL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase IIIb Study Comparing Two Boosted Protease Inhibitor-based HAART Regimens in HIV-infected Patients Experiencing Their First Virologic Failure While Receiving an NNRTI-containing HAART Regimen
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Atazanavir+ritonavir|DRUG: Lopinavir+ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: One-stage Versus Two-stage Inverted U-shaped Ridge Splitting
Status: COMPLETED
Conditions: Maxillary Ridge Augmentation
Interventions: PROCEDURE: One stage ridge splitting with simultaneous implant placement|PROCEDURE: Two-stage ridge splitting with implant placement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Post-partum Perineal Pain - Chirocaine®
Status: COMPLETED
Conditions: Post-partum Perineal Pain|Episiotomy|Vaginal Tear
Interventions: DRUG: Chirocaine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Improving Motor Function After Spinal Cord Injury
Status: COMPLETED
Conditions: Spinal Cord Injury
Interventions: DEVICE: rTMS|DEVICE: Sham rTMS|OTHER: Training|OTHER: Motor Task
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Systemic Inflammation and Obstructive Sleep Apnea Syndrome: Effect of Atorvastatin
Status: TERMINATED
Conditions: Obstructive Sleep Apnea Syndrome
Interventions: DRUG: Atorvastatin treatment|OTHER: CPAP device|OTHER: sham CPAP treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neuromuscular Electrical Stimulation in Chronic Low Back Pain
Status: COMPLETED
Conditions: Low Back Pain
Interventions: OTHER: Neuromuscular electrical stimulation and core stabilization exercise|OTHER: Sham neuromuscular electrical stimulation and core stabilization exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: OSTAP Versus TAP for Postoperative Pain Management in Laparoscopic Cholecystectomy Patients
Status: COMPLETED
Conditions: Pain Postoperative
Interventions: PROCEDURE: TAP|PROCEDURE: OSTAP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Clinical Study of a Preoperative Translational Therapy for Unresectable Gallbladder Cancer
Status: NOT_YET_RECRUITING
Conditions: Unresectable Gallbladder Cancer
Interventions: DRUG: Carrilizumab plus GEMOX
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Elderly Patients With Type 2 Diabetes and Cognitive Exercises
Status: RECRUITING
Conditions: Cognitive Impairment|Diabetes Mellitus, Type 2|Diabetes Complications
Interventions: OTHER: Educational video program|OTHER: A mobile application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy and Safety of SHR3824 in Combination With Metformin in Subjects With Type 2 Diabetes
Status: UNKNOWN
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Placebo|DRUG: SHR3824|DRUG: metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sacrocolpopexy With Posterior Repair Obstructed Defecation Symptoms
Status: ACTIVE_NOT_RECRUITING
Conditions: Vaginal Prolapse
Interventions: PROCEDURE: Laparoscopic Sacrocolopopexy|PROCEDURE: Posterior repair
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Role of Microbiome Reprogramming on Liver Fat Accumulation
Status: TERMINATED
Conditions: NAFLD
Interventions: DIETARY_SUPPLEMENT: Inulin|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: To Compare Treatment With Doxorubicin or Capecitabine for Metastatic Breast Cancer in Women 60 Years and Older
Status: TERMINATED
Conditions: Metastatic Breast Cancer
Interventions: DRUG: Pegylated liposomal doxorubicin|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Absorption Distribution Metabolism and Excretion of AQX-1125
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: AQX-1125 Oral Tablet|DRUG: [14C]-AQX-1125 IV|DRUG: [14C]-AQX-1125 Oral Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Phase I Trial of PCLX-001 in R/R Advanced Solid Malignancies and B-cell Lymphoma
Status: RECRUITING
Conditions: B-cell Non Hodgkin Lymphoma|Advanced Solid Tumor
Interventions: DRUG: PCLX-001
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: POEM (Practice of Embracing Each Moment) Study (Delivery Science)
Status: COMPLETED
Conditions: Advanced Cancer|Depression|Anxiety
Interventions: BEHAVIORAL: Mindfulness meditation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Efficacy of Hypertonic Dextrose Injection to Anterior Talofibular Ligament Sprain
Status: UNKNOWN
Conditions: Ankle Sprains
Interventions: PROCEDURE: Sham injection|PROCEDURE: Tendon injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Systemic Microvascular Reactivity After Ingestion of an Energy Drink in Young Male Volunteers
Status: COMPLETED
Conditions: Endothelial Function
Interventions: DIETARY_SUPPLEMENT: Ingestion of the energy drink (Red Bull®)|DIETARY_SUPPLEMENT: Ingestion of mineral water
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Assessment of Clinical Efficacy of Topical Application of 5% Thymoquinone Gel for Gingivitis Patients
Status: UNKNOWN
Conditions: Gingivitis
Interventions: BIOLOGICAL: 5% thymoquinone (TQ) gel|BIOLOGICAL: SRP and placebo|PROCEDURE: Only SRP-one stage prophylaxis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Antineoplaston Therapy in Treating Patients With Recurrent or Stage IV Lung Cancer
Status: TERMINATED
Conditions: Stage IV Lung Cancer
Interventions: DRUG: Antineoplaston therapy (Atengenal + Astugenal)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing the Drug Exposure in Humans After Administration of a 50 mg Tablet of Sertraline Hydrochloride as Compared to a 50 mg Capsule of Sertraline Hydrochloride Under Fasted (Nonfed) Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: sertraline hydrochloride|DRUG: sertraline hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of DC-CIK to Treat NPC
Status: UNKNOWN
Conditions: Nasopharyngeal Carcinoma
Interventions: BIOLOGICAL: DC-CIK|BIOLOGICAL: Dendritic and Cytokine-induced Killer Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Intermittent Caloric Restriction in Youth With Cardiometabolic Risk
Status: COMPLETED
Conditions: Overweight|Obesity|Cardiometabolic Risk
Interventions: BEHAVIORAL: Intermittent caloric restriction|BEHAVIORAL: Low carbohydrate diet|BEHAVIORAL: Health education on reducing the cardiometabolic risk
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: What is the Optimal Training Model for Cervical Awareness?
Status: ACTIVE_NOT_RECRUITING
Conditions: HPV Infection|Cervical Cancer|Cervical Dysplasia
Interventions: BEHAVIORAL: Education Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: CES and EGChatbot in Reducing Anxiety, Depression, Insomnia, and Mental Risk
Status: NOT_YET_RECRUITING
Conditions: Depression, Anxiety
Interventions: BEHAVIORAL: Both EGChat and CES intervention|OTHER: Exercise Chatbot|DEVICE: CES (Cranial Electrotherapy Stimulation)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of PEEP Effect on Perioperative Oxygenation and Postoperative Pulmonary Complications in Lithotomy Position
Status: UNKNOWN
Conditions: Positive End Expiratory Pressure|Lung Ultrasound
Interventions: DIAGNOSTIC_TEST: PEEP|DIAGNOSTIC_TEST: ZEEP
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: An Exploratory Study to Evaluate the Prophylactic Efficacy of a Single Immunization of Ad26.RSV.preF Against Respiratory Syncytial Virus Infection in a Virus Challenge Model in Healthy 18 to 50 Year-old Adults
Status: COMPLETED
Conditions: Healthy
Interventions: BIOLOGICAL: Ad26.RSV.preF|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Behavioural Activation Treatment for Smoking Cessation and Depressive Symptomatology: a Randomized Controlled Trial
Status: COMPLETED
Conditions: Smoking
Interventions: BEHAVIORAL: Standard cognitive-behavioural smoking cessation treatment|BEHAVIORAL: Standard cognitive-behavioural smoking cessation treatment and behavioural activation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of Gentuximab in Combination With Almonertinib in EGFR Mutation-positive Metastatic NSCLC
Status: UNKNOWN
Conditions: Metastatic Non-Small Cell Lung Cancer
Interventions: DRUG: Gentuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Study the Effect of Investigational Product on Fatigue and Cardiorespiratory Fitness in Healthy Adults.
Status: COMPLETED
Conditions: Fatigue
Interventions: OTHER: E-OJ-01|OTHER: Microcrystalline cellulose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: OTHER
Clinical trial: Immunogenicity of Co-administered Yellow Fever and Measles, Mumps, and Rubella (MMR) Vaccines
Status: COMPLETED
Conditions: Vaccine Response Impaired
Interventions: BIOLOGICAL: Co-administration of MMR/YF|BIOLOGICAL: MMR followed by YF|BIOLOGICAL: YF followed by MMR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Phase 1b/2a Study to Evaluate Safety and Efficacy of Setmelanotide in Obese Patients
Status: COMPLETED
Conditions: Overweight and Obesity
Interventions: DRUG: Setmelanotide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Nebulized Magnesium Sulfate in Children With Moderate to Severe Asthma Exacerbation
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Nebulized magnesium sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Does TMS Affect Neuroplasticity? The Role of Brain-derived Neurotrophic Factor and Neuronal Cell Adhesion Molecules - an Intensive Clinical Protocol Among Patients With Obsessive-compulsive Disorders
Status: COMPLETED
Conditions: OCD
Interventions: DEVICE: continuous theta burst stimulation - cTBS
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Acute Cardiovascular Effects of Nicotine in E-cigarettes (ACE) Study
Status: WITHDRAWN
Conditions: Cigarette Smoking Toxicity|Nicotine|Acute Cardiovascular Disease
Interventions: DRUG: Prazosin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Body Composition and Nutritional Status in Pediatric Patients With Hematological Malignancies
Status: RECRUITING
Conditions: Childhood Cancer|Child Malnutrition|Childhood Obesity
Interventions: DIAGNOSTIC_TEST: D2O dilution technique
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Evaluation of Pharmacokinetics Profiles and Bactericidal Activity of Zabofloxacin
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Zabofloxacin 183mg|DRUG: Levofloxacin 250mg|DRUG: Zabofloxacin 367mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Fasting Study of Metolazone Tablets 10 mg and Zaroloxyn® Tablets 10 mg
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Metolazone Tablets 10 mg|DRUG: Zaroloxyn® Tablets 10 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study to Evaluate the Safety and Efficacy of NG101 in Adult Participants With Symptomatic Diabetic or Idiopathic Gastroparesis
Status: COMPLETED
Conditions: Diabetic Gastroparesis|Idiopathic Gastroparesis
Interventions: DRUG: NG101|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: KLH Challenge to Explore the Human Immune Response
Status: RECRUITING
Conditions: Immune Response
Interventions: BIOLOGICAL: Keyhole-Limpet Hemocyanin|DRUG: Saline|DRUG: Montanide ISA 51 VG|DRUG: Alhydrogel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Chronic Pancreatitis. Effect of Pioglitazone on Endocrine Function, Exocrine Function & Structure, Pain & Life Quality
Status: COMPLETED
Conditions: Chronic Pancreatitis|Insulin Resistance|Normal or Mildly Abnormal Stool Fat Levels
Interventions: DRUG: Pioglitazone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Programmes de Marche Active et qualité de Vie Dans la Maladie de Parkinson
Status: WITHDRAWN
Conditions: Parkinson Disease
Interventions: BEHAVIORAL: Physical training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Prophylactic Peripheral Iridectomy Prevents Aphakic Angle-closure Glaucoma
Status: COMPLETED
Conditions: Congenital Cataract|Aphakic Glaucoma
Interventions: PROCEDURE: PPI group|PROCEDURE: cataract extraction
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: CETIC-I (CEra Traction Improves Cervical Kyphosis -I)
Status: NOT_YET_RECRUITING
Conditions: Cervical Kyphosis|Cervical Lordosis|Kyphosis
Interventions: DEVICE: CGM MB-1701 device treatment|DEVICE: CGM MB-1701 Sham device treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Checklists in Surgical Care - a Study on Complications, Death and Quality of Patient Administrative Data
Status: COMPLETED
Conditions: Postoperative Complications|Complications of Surgical Procedures or Medical Care
Interventions: OTHER: The comprehensive patient safety checklist system
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study Impact on Outcome of Eltrombopag in Elderly Patients With Acute Myeloid Leukemia Receiving Induction Chemotherapy
Status: UNKNOWN
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Eltrombopag|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Hyalase Hydro-dissection in Treatment of Carpal Tunnel: Randomized Double Blind Controlled Clinical Trial
Status: COMPLETED
Conditions: Carpal Tunnel Syndrome
Interventions: DRUG: Hyalase|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Direct Laryngoscopy With Blind Intubation Via Intubating Laryngeal Tube Suction Disposable
Status: UNKNOWN
Conditions: Adverse Anesthesia Outcome
Interventions: DEVICE: Intubating Laryngeal Tube Suction|DEVICE: Direct Laryngoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Pain Science Education in People With Symptomatic Knee Osteoarthritis
Status: COMPLETED
Conditions: Osteo Arthritis Knee
Interventions: OTHER: Pain science education driven physiotherapy program|OTHER: Biomedical education driven physiotherapy program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Trial Of Azithromycin SR For The Treatment Of Mild To Moderate Community Acquired Pneumonia In Japanese Adults
Status: COMPLETED
Conditions: Pneumonia, Community-Acquired
Interventions: DRUG: Azithromycin SR
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of mCIMT vs CT on Upper Extremity Motor Function and ADLs in Chronic Stroke Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Stroke
Interventions: BEHAVIORAL: modified constraint induced movement therapy (mCIMT)|COMBINATION_PRODUCT: conservative treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Comparison of Hylastan to Methylprednisolone Acetate in Patients With Symptomatic Osteoarthritis of the Knee
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: DEVICE: Hylastan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Postoperative Pain After Using NiTi Instruments
Status: COMPLETED
Conditions: Post-Op Complication|Endodontic Inflammation|Endodontically Treated Teeth|Apical Periodontitis
Interventions: PROCEDURE: NiTi instruments
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Experimental Denture Pastes
Status: COMPLETED
Conditions: Dental Plaque|Denture Stomatitis|Oral Candidiasis|Oral Hygiene
Interventions: OTHER: Dentifrice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effectiveness of Selective Nerve Root Injections in Preventing the Need for Surgery
Status: COMPLETED
Conditions: Radiculopathy
Interventions: DRUG: Kenalog and Sensorcaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: VERIFY: Vedolizumab for the Prevention of Immune Checkpoint Inhibitor Related Diarrhea or Colitis in Patients With Cancer
Status: NOT_YET_RECRUITING
Conditions: Cancer|Cancer Metastatic
Interventions: BIOLOGICAL: Vedolizumab|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy Study of Erythropoietin as add-on Therapy of Methylprednisolone to Treat Acute Optic Neuritis
Status: COMPLETED
Conditions: Optic Neuritis
Interventions: DRUG: Erythropoietin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Identification of Response to Hypertonic Dextrose Prolotherapy Markers in Knee Osteoarthritis Patients by Cytokine Array
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: DRUG: hypertonic dextrose prolotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Between the Analgesic Efficacy of Erector Spinae Plane Block and Psoas Compartment Block in Hip Surgery
Status: UNKNOWN
Conditions: Hip Arthropathy
Interventions: PROCEDURE: Psoas Compartment Block Group (GROUP I)|PROCEDURE: Erector Spinae Plane block ( Group II)|PROCEDURE: Control Group (GROUP III)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of CE-224,535 A Twice Daily Pill To Control Rheumatoid Arthritis In Patients Who Have Not Totally Improved With Methotrexate
Status: COMPLETED
Conditions: Arthritis, Rheumatoid
Interventions: DRUG: CE-224,535|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: NIche Development With Closure of Cesarean Uterotomy by Modified or Conventional Two-layer Technique
Status: UNKNOWN
Conditions: Cesarean Scar Niche
Interventions: PROCEDURE: Conventional|PROCEDURE: Modified
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Biphasic Insulin Aspart Versus NPH Plus Regular Human Insulin in Type 2 Diabetic Patients
Status: COMPLETED
Conditions: Diabetes Type 2
Interventions: DRUG: BIAsp 30|DRUG: NPH/Reg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Anti-PD-1 Plus Chemotherapy in Locally Advanced Resectable Esophageal Squamous Cell Carcinoma
Status: RECRUITING
Conditions: Esophageal Squamous Cell Carcinoma|Neoadjuvant Chemoimmunotherapy
Interventions: DRUG: neoadjuvant anti-PD-1 plus chemotherapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: STeP IT UP CF: STimulating ImProved Health And Well-being In CysTic Fibrosis
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DEVICE: Fitbit Tracker
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: 17% Salicylate Versus 17% Salicylate-Ethyl Pyruvate for Plantar Foot Warts
Status: UNKNOWN
Conditions: Warts
Interventions: DRUG: 17% Salicylate with ethyl pyruvate|DRUG: Salicylates
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Test to Treat TB: Impact of Sputum Sequencing-guided Individualised Therapy on Outcomes in Drug-resistant Tuberculosis
Status: NOT_YET_RECRUITING
Conditions: Tuberculosis, Multidrug-Resistant
Interventions: DIAGNOSTIC_TEST: Targeted sequencing using the GenoScreen Deeplex assay
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Influence of Epidural Analgesia in Elective Laparoscopic Colorectal Resections
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: epidural analgesia (Duracain/Fentanyl/Naropin)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Povidone-iodine and the Normal Saline Cleaning the Incision for the SSIs
Status: UNKNOWN
Conditions: Surgical Site Infections|Gastric Cancer|Dehiscence of Laparotomy Wound
Interventions: PROCEDURE: Group A (povidone-iodine wash the surgical incision)|PROCEDURE: Group B (normal saline wash the surgical incision)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vorinostat and Bortezomib in Treating Patients With Advanced Soft Tissue Sarcoma
Status: COMPLETED
Conditions: Recurrent Adult Soft Tissue Sarcoma|Stage III Adult Soft Tissue Sarcoma|Stage IV Adult Soft Tissue Sarcoma
Interventions: DRUG: vorinostat|DRUG: bortezomib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Mechanisms of Energy Medicine to Decrease Chronic Knee Pain in Outpatient Settings
Status: TERMINATED
Conditions: Ostheoporosis of the Knee
Interventions: PROCEDURE: Acupuncture|PROCEDURE: Enery Medicine Intervention|PROCEDURE: Sham Energy Medicine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: High Dose Ruxolitinib and Allogeneic Stem Cell Transplantation in Myelofibrosis Patients With Splenomegaly
Status: NOT_YET_RECRUITING
Conditions: Splenomegaly|Myelofibrosis
Interventions: DRUG: Ruxolitinib|PROCEDURE: Allogeneic Stem Cell Transplantation|DRUG: Levetiracetam|DRUG: Eltrombopag|DRUG: Busulfan|DRUG: Romiplostim|DRUG: Fludarabine phosphate|DRUG: Cyclophosphamide|DRUG: Mesna|DRUG: Tacrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Is Real-time CGM Superior to Flash Glucose Monitoring in Real Life Study (CORRIDA LIFE)
Status: UNKNOWN
Conditions: Diabetes Mellitus, Type 1
Interventions: DEVICE: Continuous Glucose Monitoring Dexcom G5 and G6 system (real-time continuous glucose monitoring)|DEVICE: Continuous Glucose Monitoring FreeStyle Libre Flash system (flash glucose monitoring)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Screening and Support for Youth (SASY) Intervention to Reduce Mental Health Disparities
Status: NOT_YET_RECRUITING
Conditions: Adolescent Health|Minority Health|Mental Health|Community Health Services
Interventions: BEHAVIORAL: Behavioral: Screening and Support for Youth (SASY) Multi-component Platform: includes screening, feedback, single session intervention, and resource information|BEHAVIORAL: Behavioral: Screening and Support for Youth (SASY) Multi-component Platform: includes screening, feedback, single session intervention, and resource information
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Home Based Tele-exercise for People With Chronic Neurological Impairments
Status: ACTIVE_NOT_RECRUITING
Conditions: Neurologic Disorder|Stroke|Spinal Cord Injuries|Cerebral Palsy|Hemiplegia|Hemiparesis|Multiple Sclerosis|Parkinson Disease|Trauma, Brain|Transverse Myelitis|Friedreich Ataxia
Interventions: BEHAVIORAL: Seated exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BOLD MRI and FMISO PET for the Assessment of Hypoxic Tumor Microenvironment in Patients With Oligometastatic Liver Cancer Undergoing Yttirum-90 Selective Internal Radiation Therapy
Status: RECRUITING
Conditions: BCLC Stage A Hepatocellular Carcinoma|BCLC Stage B Hepatocellular Carcinoma|BCLC Stage C Hepatocellular Carcinoma|Hepatocellular Carcinoma
Interventions: OTHER: 18F-Fluoromisonidazole|PROCEDURE: Biopsy|PROCEDURE: Dynamic Contrast-Enhanced Magnetic Resonance Imaging|PROCEDURE: Positron Emission Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Glycerol-Electrolyte Beverages on Fluid Balance in Healthy Euhydrated Men and Women at Rest
Status: RECRUITING
Conditions: Hydration
Interventions: OTHER: Beverage. Incomplete block where each participant will complete 3 of the 6 possible glycerol-sodium blends in random order.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Investigating the Effects of Rhythm and Entrainment on Fluency in People With Aphasia
Status: RECRUITING
Conditions: Aphasia|Apraxia of Speech
Interventions: BEHAVIORAL: Unison speech (vs. solo)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: RHA® 4 With New Anesthetic - Nasolabial Folds
Status: COMPLETED
Conditions: Aging|Pain
Interventions: DEVICE: RHA®4 with new anesthetic agent|DEVICE: RHA®4-Lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Switch From Etanercept to Infliximab in Subjects With Moderate-to-Severe Psoriasis (Study P05133)
Status: COMPLETED
Conditions: Psoriasis
Interventions: BIOLOGICAL: Infliximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antiglutamate Anticonvulsants in the Treatment of Alcohol Withdrawal Syndrome
Status: COMPLETED
Conditions: Topiramate|Lamotrigine|Memnatine|Diazepam|Placebo
Interventions: DRUG: Anticonvulsants
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Endometriosis With 18F-fluorofuranylnorprogesterone PET / MRI
Status: RECRUITING
Conditions: Endometriosis
Interventions: DRUG: 18F-fluorofuranylnorprogesterone PET / MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Repetitive Transcranial Magnetic Stimulation in Post Stroke Upper Limb Spasticity
Status: COMPLETED
Conditions: Spasticity as Sequela of Stroke
Interventions: DEVICE: Repetitive transcranial magnetic stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Regeneration of Intrabony Defects With Nano Hydroxyapatite Graft, and Periosteum as Barrier Membrane Under Magnification
Status: UNKNOWN
Conditions: Intrabony Periodontal Defect
Interventions: PROCEDURE: Regeneration of Intrabony Defects with Nano Hydroxyapatite Graft, Derived from Egg Shell along with Periosteum as Barrier Membrane|PROCEDURE: Regeneration of intrabony defects using Egg shell derived nano hydroxyapatite (EnHA) as regenerative graft material|PROCEDURE: Open flap debridement procedure in intrabony defects.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Prognostic Indicators as Provided by the EPIC ClearView
Status: COMPLETED
Conditions: Coronary Artery Disease|Congestive Heart Failure|Valvular Heart Disease|Atrial Fibrillation|Hypertension|Pyelonephritis|Acute Renal Failure|Renal Failure|Viral Hepatitis|Alcoholic Hepatitis|Steatohepatitis|Cirrhosis|Asthma|COPD|Bronchitis|Emphysema|Pneumonia|Inflammatory Bowel Disease|Crohn's Disease|Ulcerative Colitis|Diverticulitis|Peptic Ulcer Disease|Irritable Bowel Syndrome|Cholecystitis|Pancreatitis|Malabsorption Disorders|Celiac Sprue|Diabetes
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pregnancy and Neonatal Follow-up of Ongoing Pregnancies Established During Phase II Clinical Trials of Org 36286 (Study 38817)(P06054)(COMPLETED)
Status: COMPLETED
Conditions: Pregnancy
Interventions: DRUG: Org 36286 (corifollitropin alfa)|DRUG: Placebo|DRUG: recFSH
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Closed or Open Abdomen for the Management of Abdominal Sepsis
Status: RECRUITING
Conditions: Abdominal Sepsis|Abdominal Infection
Interventions: DEVICE: Open Abdomen Management with ANPPT dressing|OTHER: Closed Abdomen Management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Recombinant Human Erythropoietin in Anemic Cancer Patients Undergoing Chemotherapy
Status: COMPLETED
Conditions: Chemotherapy Induced Anemia
Interventions: DRUG: recombinant human erythropoietin|DRUG: recombinant human erythropoietin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT