pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Study of SKB264 for the Treatment of Participants With Advanced or Metastatic Non-small Cell Lung Cancer (NSCLC)
Status: RECRUITING
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: SKB264|DRUG: Pembrolizumab|DRUG: Carboplatin|DRUG: Osimertinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Telemonitoring of Uncontrolled Hypertension
Status: WITHDRAWN
Conditions: Hypertension
Interventions: DEVICE: Omron 9200T plus Telemonitoring|DEVICE: Omron 9200T without Telemonitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cefadroxil and Cephalexin Drug Levels and Dosing in Pediatric Musculoskeletal Infections
Status: COMPLETED
Conditions: Osteomyelitis|Septic Arthritis|Pyomyositis
Interventions: DRUG: Cefadroxil|DRUG: Cephalexin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Therapeutic Potential for Aldosterone Inhibition in Duchenne Muscular Dystrophy
Status: COMPLETED
Conditions: Duchenne Muscular Dystrophy
Interventions: DRUG: Eplerenone|DRUG: Spironolactone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Hyperbaric Oxygen Therapy on Patients Suffering From Neurologic Deficiency Due Traumatic Brain Injury
Status: COMPLETED
Conditions: Neurologic Deficiency|Traumatic Brain Injury
Interventions: PROCEDURE: Hyperbaric Oxygen Therapy (HBOT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Virtual Reality in Teachers' Vocal Motor Behavior Acquisition (VirtuVox)
Status: COMPLETED
Conditions: Voice Disorders|Virtual Reality Therapy
Interventions: BEHAVIORAL: Direct Method|BEHAVIORAL: Indirect Method
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Pharmacokinetic Profile (How the Body Absorbs, Distributes, Metabolizes and Eliminates a Drug) of TMC125 Plus Tenofovir/Emtricitabine Once Daily With or Without Darunavir/r Once Daily in Antiretroviral (ARV) Naive HIV-1 Patients (Patients Have Never Received ARV Treatment).
Status: COMPLETED
Conditions: HIV-1 Infection
Interventions: DRUG: TMC125; darunavir; ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparative Study Between Oncoplastic Breast Surgery and Standard Conservative Surgery:Margin Status and Patient Satisfaction
Status: COMPLETED
Conditions: Breastcancer
Interventions: PROCEDURE: Standard conservative breast surgery|PROCEDURE: Oncoplastic breast surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Learning Method (CAM-ICU) Between E-learning and Conventional Face-to-face Lecture and Demonstration
Status: COMPLETED
Conditions: Delirium
Interventions: OTHER: learning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Biphasic Effects of Different Doses Ephedrine on Hemodynamics in Elderly Patients Under General Anesthesia
Status: UNKNOWN
Conditions: Blood Pressure
Interventions: DRUG: Ephedrine|DRUG: Ephedrine|DRUG: Ephedrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Randomized Controlled Trial Testing the Effect of the Youth Mindful Awareness Program on Negative Affect (YMAP2).
Status: RECRUITING
Conditions: Prevention|Control
Interventions: BEHAVIORAL: Mindfulness Program|BEHAVIORAL: Active Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Consolidative Radiotherapy for Colorectal Cancer Liver Metastases Receiving Surgery or Radiofrequency Ablation
Status: WITHDRAWN
Conditions: Radiotherapy|Colorectal Cancer|Liver Metastases
Interventions: RADIATION: adjuvant SBRT|DRUG: Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Do Changes in ctDNA Predict Response for Patients With Oesophageal Cancer Receiving Durvalumab
Status: ACTIVE_NOT_RECRUITING
Conditions: Oesophageal Cancer
Interventions: DRUG: Durvalumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Relative Bioavailability Study of Metformin HCl 750 mg ER Tablets Under Non-fasting Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Metformin HCl 750 mg Extender Release tablets, single dose|DRUG: GLUCOPHAGE® XR 750 mg tablets, single dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Evaluation of a Scalable Decision Support and Shared Decision Making Tool for Lung Cancer Screening
Status: ACTIVE_NOT_RECRUITING
Conditions: Early Detection of Cancer|Lung Neoplasms
Interventions: OTHER: EHR-integrated Shared Decision Making Tool and Clinical Decision Support for Lung Cancer Screening
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Tumor Hypoxia and Proliferation in Patients With High-Grade Glioma
Status: RECRUITING
Conditions: Glioma
Interventions: DRUG: 18F-FMISO PET|DRUG: 18F-FLT PET
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effect of Education and Telephone Follow-up Given to Cancer Patients Receiving Immunotherapy on Symptom Management and Self-care Power
Status: UNKNOWN
Conditions: Self Care|Symptom Management|Immunotherapy|Cancer Patient
Interventions: DEVICE: TRAINING BOOKLET
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study Comparing Standard Care for Diabetes to Case-Managed Care for Diabetes in Patients With Coronary Artery Disease
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Coronary Disease
Interventions: BEHAVIORAL: Consultation with Endocrinologist|BEHAVIORAL: Counseling from Dietician|BEHAVIORAL: Counseling from Diabetes Educator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Preventing Preterm Birth With a Negative Pressure Cervical Cup: a Feasibility Study
Status: UNKNOWN
Conditions: Preterm Birth|Cervical Incompetence|Cervical Insufficiency|Short Cervix|Soft Cervix
Interventions: DEVICE: Hannah Cervical Cup (2 mm Delta)|DEVICE: Hannah Cervical Cup (4 mm Delta)|DEVICE: Hannah Cervical Cup (6 mm Delta)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Technology Assisted Nudging to Increase Physical Activity Among Hospitalised Medical Patients
Status: RECRUITING
Conditions: COPD|Heart Failure|Parkinson Disease|Arthritis|Old Age; Cachexia|Stroke Sequelae
Interventions: BEHAVIORAL: Digital nudging intervention target to change behavior
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Testing the Addition of Activity Monitoring With a Wearable Electronic Device to Improve Patient Care During Treatment for Lung Cancer
Status: TERMINATED
Conditions: Non-small Cell Lung Cancer|Non-small Cell Lung Cancer Stage III|Recurrent Non Small Cell Lung Cancer
Interventions: OTHER: Garmin Vivofit Activity Tracker
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Chemotherapy Plus Interferon Alfa Alone or With Radiation Therapy and Peripheral Stem Cell Transplantation in Treating Patients With Stage III or Stage IV Follicular Non-Hodgkin's Lymphoma
Status: TERMINATED
Conditions: Lymphoma
Interventions: BIOLOGICAL: filgrastim|BIOLOGICAL: recombinant interferon alfa|DRUG: cyclophosphamide|DRUG: prednisone|DRUG: vincristine sulfate|PROCEDURE: autologous bone marrow transplantation|PROCEDURE: bone marrow ablation with stem cell support|PROCEDURE: peripheral blood stem cell transplantation|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Effect of Hydrocortisone Iontophoresis Versus Hydrocortisone Phonophoresis On Post Surgical Scar
Status: COMPLETED
Conditions: Scar|Hydrocortisone|Iontophoresis|Phonophoresis
Interventions: OTHER: Iontophoresis|OTHER: Phonophoresis|OTHER: traditional PT program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of VagiVitalAC for Treatment of Candida Vulvovaginitis
Status: UNKNOWN
Conditions: Vaginal Candidiasis|Vulvovaginal Candidiasis|Candidal Vulvovaginitis
Interventions: DEVICE: VagiVitalAC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effect of Intravitreal Injections of Anti-VEGF on Macular Perfusion in Diabetic Patients Using OCTA
Status: COMPLETED
Conditions: Diabetic Macular Edema|Ischemic Maculopathy
Interventions: DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Concentration of Ertapenem in Colorectal Tissue
Status: COMPLETED
Conditions: Diverticulosis, Colonic|Rectal Neoplasms|Colonic Neoplasms
Interventions: DRUG: Ertapenem
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of DermStream(tm) - an Irrigation Product for Chronic Wound Management
Status: COMPLETED
Conditions: Venous Insufficiency|Diabetes
Interventions: DEVICE: DermaStream(tm) application and Streaming of Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Postprandial Walking in Obese Pregnant Women and Perinatal Outcomes - a Multicenter Randomized Clinical Trial
Status: WITHDRAWN
Conditions: Obesity|Gestational Diabetes|Preeclampsia
Interventions: BEHAVIORAL: Postprandial walks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Nutrition, Vision, and Cognition in Sport Study: Beef
Status: UNKNOWN
Conditions: Cognitive Change|Nutrient Deficiency|Nutritional Anemia|Visual Spatial Processing|Diet, Healthy|Diet; Deficiency|Dietary Deficiency|Dietary B12 Deficiency|Dietary Zinc Deficiency|Dietary Vitamin B12 Deficiency Anemia|Dietary Deficiency of Selenium and Vitamin E
Interventions: DIETARY_SUPPLEMENT: 30 day Daily consumption of 1 serving of beef|DIETARY_SUPPLEMENT: 30 day Daily consumption of 1 serving of the vegatable protein source
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility Study of Pemetrexed in Combination With Cisplatin or Carboplatin as Adjuvant Treatment of Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: pemetrexed|DRUG: cisplatin|DRUG: carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Venetoclax in Combination With Low Dose Cytarabine Versus Low Dose Cytarabine Alone in Treatment Naive Patients With Acute Myeloid Leukemia Who Are Ineligible for Intensive Chemotherapy
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Myeloid Leukemia (AML)
Interventions: DRUG: Placebo|DRUG: Venetoclax|DRUG: Cytarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Oral Dydrogesterone in the Management of Preterm Labor
Status: COMPLETED
Conditions: Preterm Labor
Interventions: DRUG: Dydrogesterone|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness and Safety of EuBone® Capsules for Bone Health in Postmenopausal Women
Status: UNKNOWN
Conditions: Osteoporosis, Postmenopausal
Interventions: DRUG: EuBone ® capsule|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Boneview-ED - Impact of Artificial Intelligence Detecting Fractures in the Emergence Department : a Pragmatic Prospective Study
Status: RECRUITING
Conditions: Fractures, Bone
Interventions: DIAGNOSTIC_TEST: processing the radiography with the "Boneview" software
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effect of Direct Cyclophotocoagulation Using Endolaser in Silicon Induced Glaucoma: a Pilot Study.
Status: COMPLETED
Conditions: Glaucoma
Interventions: PROCEDURE: Cyclophotocoagulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lutronic LaseMD for Treatment of Benign Pigmented Lesions
Status: COMPLETED
Conditions: Benign Pigmented Lesions
Interventions: DEVICE: LaseMD and DUAL 1927nm Laser|DEVICE: LaseMD
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of DR-0201 in Healthy Adult Volunteers
Status: COMPLETED
Conditions: Healthy Adult Volunteers
Interventions: DRUG: DR-0201|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Synergistic Immunomodulatory Effect of Synbiotics Pre and Postoperative Resection of Pancreatic Ductal Adenocarcinoma
Status: COMPLETED
Conditions: Pancreatic Ductal Adenocarcinoma
Interventions: DIETARY_SUPPLEMENT: probiotic agent 25 Billion CFU (Nowfoods, USA) , ). Inulin capsules 1000mg Herbamama USA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy and Safety Evaluation of IBI188 in Combination With Demethylating Agents in Treatment of Patients With Acute Myeloid Leukemia
Status: SUSPENDED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: IBI188|DRUG: Azacitidine|DRUG: Decitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study of hMN14 to Treat Either Colorectal or Breast Cancer
Status: COMPLETED
Conditions: Colorectal Cancer|Colon Cancer|Rectal Cancer|Colorectal Neoplasms|Colorectal Carcinoma|Breast Cancer|Breast Neoplasms
Interventions: DRUG: hMN14 (labetuzumab)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose Ranging Study of Ba 679 BR Inhalation Powder in Chronic Obstructive Pulmonary Disease (COPD) Patients
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Ba 679 BR low dose|DRUG: Ba 679 BR middle dose|DRUG: Ba 679 BR high dose|DRUG: Placebo inhalation powder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Lurasidone - A 6-week Study of Patients With Bipolar I Depression (Add-on)
Status: COMPLETED
Conditions: Bipolar Depression
Interventions: DRUG: lurasidone + (lithium or divalproex)|DRUG: Placebo + (lithium or divalproex)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Quantitative Assessment of Training Effects Using EKSOGT Exoskeleton in Quantitative Assessment of Training Effects Using EKSOGT Exoskeleton in Parkinson Disease Patients
Status: UNKNOWN
Conditions: Parkinson Disease
Interventions: DEVICE: Experimental: EksoGT|OTHER: Functional kinematic training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Lymphocyte Depletion and Stem Cell Transplantation to Treat Severe Systemic Lupus Erythematosus
Status: COMPLETED
Conditions: Lupus Erythematosus, Systemic
Interventions: DRUG: fludarabine phosphate|DRUG: cyclophosphamide|BIOLOGICAL: Rituxan (rituximab)|BIOLOGICAL: filgrastim|DRUG: methylprednisolone|OTHER: immunologic technique|OTHER: laboratory biomarker analysis|PROCEDURE: autologous hematopoietic stem cell transplantation|DRUG: Diphenhydramine|DRUG: Mesna
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Patient Specific Instrumentation in ACL Reconstruction
Status: NOT_YET_RECRUITING
Conditions: Anterior Cruciate Ligament Injuries
Interventions: DEVICE: ACL reconstruction using the SONAR Femoral Aimer PSI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Cognitive-Behavioral and Pharmacologic (LDX) Treatment of Binge-Eating Disorder and Obesity: Maintenance Treatment
Status: ACTIVE_NOT_RECRUITING
Conditions: Binge-Eating Disorder|Obesity
Interventions: DRUG: Lisdexamfetamine Dimesylate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mascot Study: Management of Atrial Fibrillation (AF) Suppression in AF-Heart Failure (HF) COmorbidity Therapy
Status: COMPLETED
Conditions: Heart Failure|Atrial Fibrillation|Ventricular Dysfunction
Interventions: DEVICE: Atrial Overdrive Pacing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Method Evaluation Study of Truview Picture Capture Device(PCD) Versus MacIntosh Laryngoscope
Status: COMPLETED
Conditions: Intubation
Interventions: PROCEDURE: Truwiev PCD laryngoscope
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of the Effects of Four Different Flap Designs on Tissue Healing in Lower Third Molar Surgery
Status: ENROLLING_BY_INVITATION
Conditions: Soft Tissue Injuries
Interventions: PROCEDURE: Triangular Flap|PROCEDURE: Berwick Flap|PROCEDURE: Saurez Flap|PROCEDURE: Heitz Flap
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Single Dose, Dose Escalation Healthy Volunteers Study Of PF-05105679
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: PF-05105679|DRUG: PF-05105679|DRUG: PF-05105679
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of 188-0551 Spray Versus Vehicle Spray in Subjects With Plaque Psoriasis (307)
Status: COMPLETED
Conditions: Plaque Psoriasis
Interventions: DRUG: 188-0551 Spray|DRUG: Vehicle Spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: QDISS Stud: QD Isentress as Switch Strategy in Virologically Suppressed HIV-1 Infected-Patient
Status: COMPLETED
Conditions: Virus-HIV
Interventions: DRUG: Raltegravir and 2 Nucleoside/Nucleotide reverse transcriptase inhibitor (NRTI)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Focused Incentive Spirometry Monitoring to Reduce Postoperative Oxygen Therapy and Respiratory Complications After Bariatric Surgery
Status: COMPLETED
Conditions: Respiratory Complication
Interventions: BEHAVIORAL: Focused incentive spirometer education and monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: To Evaluate the Efficacy and Safety of Genalumab for Injection in the Treatment of Active Systemic Juvenile Idiopathic Arthritis.
Status: NOT_YET_RECRUITING
Conditions: Active Systemic Juvenile Idiopathic Arthritis
Interventions: DRUG: GenaKumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Compare Efficacy of Low Dose Diclofenac (25mg) in Management of Postoperative Pain After Periodontal Flap Surgery
Status: COMPLETED
Conditions: Chronic Periodontitis
Interventions: DRUG: low dose diclofenac
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: US 10 mL Bronchoscopic Lung Volume Reduction (BLVR) Phase 1 Emphysema Study - Initial Formulation
Status: COMPLETED
Conditions: Pulmonary Emphysema
Interventions: BIOLOGICAL: BLVR
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Crohn's Disease With an Antibiotic Regimen Directed Against Mycobacterium Avium Paratuberculosis
Status: WITHDRAWN
Conditions: Crohn's Disease
Interventions: DRUG: Rifabutin, Clarithromycin, and Clofazimine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study on Endoscopic Management of GOV1 Esophagogastric Varices
Status: NOT_YET_RECRUITING
Conditions: Esophageal and Gastric Varices
Interventions: PROCEDURE: Endoscopic gel embolization of gastric fundus varices and ligation of esophageal varices|PROCEDURE: Endoscopic gel embolization of gastric fundus varices and sclerotherapy of esophageal varices|PROCEDURE: Endoscopic gelatinous embolization of gastric varices (esophageal varices not treated)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Noninvasive Surrogate Marker for Advanced Hepatocellular Carcinoma Response to Concurrent Chemoradiotherapy: MR Perfusion, Contrast Enhanced Ultrasound and Biomarkers
Status: UNKNOWN
Conditions: Advanced Adult Hepatocellular Carcinoma
Interventions: RADIATION: DCE MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: n-3 Polyunsaturated Fatty Acids to Prevent and Treat Diabetic Neuropathy
Status: SUSPENDED
Conditions: Diabetic Neuropathies
Interventions: DIETARY_SUPPLEMENT: Fish-oil derived n-3 polyunsaturated fatty acids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Evaluation of Paxlovid for COVID-19: a Real-world Case-control Study
Status: UNKNOWN
Conditions: COVID-19 Pneumonia
Interventions: DRUG: standard-of-care plus Paxlovid|DRUG: standard-of-care
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intermittent High-Dose Lapatinib in Tandem With Capecitabine for HER2 Overexpressed/Amplified Metastatic Breast Cancer With Central Nervous System (CNS) Metastases
Status: COMPLETED
Conditions: Metastatic Breast Cancer|Central Nervous System (CNS) Metastases
Interventions: DRUG: Lapatinib in Tandem With Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevalence of Amyloidosis in Heart Failure (PREVAMIC)
Status: UNKNOWN
Conditions: Heart Failure
Interventions: DIAGNOSTIC_TEST: Bone-cardiac scintigraphy with Tc-DPD (or similar: Tc-PYP or Tc-HMDP).|DIAGNOSTIC_TEST: Proteinogram and serum immunoglobulins. Light chains free in serum -Freelite-. Immunofixation in serum and urine
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Influence on Food Liking of Adding Spices to Replace Sugar Using CLT
Status: COMPLETED
Conditions: Normal Subjects Who Agree to Participate in Taste Testing
Interventions: OTHER: Apple Crisp|OTHER: Tea|OTHER: Oatmeal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Effect of Myofunctional Therapy on OSA
Status: RECRUITING
Conditions: Obstructive Sleep Apnea
Interventions: BEHAVIORAL: OMT Exercises|BEHAVIORAL: Nasal Breathing Exercises|OTHER: Use of Nasal Lavage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Antineoplastons A10 and AS2-1 In Patients With Carcinoma of the Bladder
Status: TERMINATED
Conditions: Stage IV Bladder Cancer
Interventions: DRUG: Antineoplaston therapy (Atengenal + Astugenal)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Immersion in Dead Sea Water on Glucose Levels in Type 2 Diabetes Mellitus Patients
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: PROCEDURE: Dead Sea water|PROCEDURE: Pool water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Postoperative Analgesic Effect Of Dexmedetomidine Administration in Wound Infiltration for Total Abdominal Hysterectomy
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Dexmedetomidine|DRUG: Levobupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Perhexiline Therapy in Patients With Hypertrophic Cardiomyopathy
Status: COMPLETED
Conditions: Hypertrophic Cardiomyopathy
Interventions: DRUG: Perhexiline/Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Stem Cell Transplant for Hemoglobinopathy
Status: COMPLETED
Conditions: Sickle Cell Disease|Thalassemia|Severe Congenital Neutropenia|Diamond-Blackfan Anemia|Shwachman-Diamond Syndrome
Interventions: DRUG: Busulfan, Fludarabine, ATG, TLI|DRUG: Busulfan, Cyclophosphamide, ATG, GCSF|DRUG: Campath, Fludarabine, Cyclophosphamide|RADIATION: Total Body Irradiation|PROCEDURE: Stem cell infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Photobiomodulation for Myofascial Pelvic Pain
Status: RECRUITING
Conditions: Pelvic Pain|Levator Ani Syndrome|Spastic Pelvic Floor Syndrome|Chronic Pelvic Pain Syndrome|Myalgia of Pelvic Floor
Interventions: DEVICE: SoLá therapy|OTHER: Pelvic floor physical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Emicizumab PUPs and Nuwiq ITI Study
Status: WITHDRAWN
Conditions: Hemophilia A
Interventions: DRUG: Nuwiq (low dose protocol)|DRUG: HEMLIBRA|DRUG: Nuwiq (Atlanta protocol)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Psychosocial and Psychophysical Factors and Preemptive Analgesia on Postoperative Pain in Upper Limb Surgery
Status: UNKNOWN
Conditions: Postoperative Pain
Interventions: COMBINATION_PRODUCT: Paracetamol and Ibuprofen|DRUG: Pregabalin 150mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Use of Prophylactic Steroids in the Prevention of Post-thyroidectomy Hypocalcaemia and Voice Dysfunction
Status: COMPLETED
Conditions: Thyroid Diseases|Hypocalcemia|Vocal Cord Dysfunction
Interventions: DRUG: Dexamethasone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: To Evaluate Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics of DWRX2003 Against COVID-19
Status: UNKNOWN
Conditions: Healthy
Interventions: DRUG: DWRX2003|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Investigational Tirzepatide (LY3298176) Doses in Participants With Type 2 Diabetes and Obesity
Status: RECRUITING
Conditions: Type 2 Diabetes|Obesity
Interventions: DRUG: Tirzepatide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Evaluate the Safety and Efficacy of JTM201 to Treat Moderate or Severe Glabellar Lines
Status: NOT_YET_RECRUITING
Conditions: Glabellar Lines
Interventions: BIOLOGICAL: JTM201|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dexmedetomidine in Mechanically Ventilated Neonates With Single-Organ Respiratory Failure.
Status: COMPLETED
Conditions: Mechanically-ventilated Neonates With Single-organ Respiratory Failure
Interventions: DRUG: Dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: tES Effects on Associative Memory Performance
Status: COMPLETED
Conditions: Healthy|Mild Cognitive Impairment|Alzheimer Disease
Interventions: DEVICE: real anodal transcranial direct current stimulation|DEVICE: real transcranial alternating current stimulation|DEVICE: sham transcranial electric current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparative Study Between Dexmedetomidine & Neostigmine as an Adjuvant to Local Anesthetic Mixture in Peribulbar Block in Vitreoretinal Surgeries
Status: COMPLETED
Conditions: Vitreoretinal Surgeries|Local Anesthesia
Interventions: DRUG: Dexmedetomidine|DRUG: Neostigmine|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Combination Chemotherapy in Treating Women With Stage IIIB or Stage IV Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: cyclophosphamide|DRUG: Taxotere|DRUG: Adriamycin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Less Chronic Pain After Lichtenstein Hernioplasty Using the Self-gripping Parietex Progrip Mesh
Status: UNKNOWN
Conditions: Hernia, Inguinal|Unilateral Inguinal Hernia
Interventions: PROCEDURE: Self-fixating Parietex Progrip Mesh
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of SGLT2 Inhibitors in Pre-heart Failure Populations With Hypertension
Status: RECRUITING
Conditions: Pre-Heart Failure|Hypertension
Interventions: DRUG: Empagliflozin 10 MG|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pharmacokinetics and Pharmacodynamics of Multiple 5 mg Doses of BI 1356 p.o. Given Once Daily Compared to Multiple 2.5 mg Doses Given Twice Daily in Healthy Male and Female Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BI 1356, high dose|DRUG: BI 1356, low dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Patient Journey Application for Discontinuing Inappropriate PPI Use: a Randomized Controlled Trial
Status: COMPLETED
Conditions: Proton Pump Inhibitor|Inappropriate Drug Use|Discontinuation|E-health
Interventions: OTHER: Patient Journey App|OTHER: Information folder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Predicting Response to Interventional Pain Management Techniques in Chronic Low Back Pain in a Prospective Cohort.
Status: COMPLETED
Conditions: Low Back Pain|Pain Measurement|Chronic Pain|Analgesia, Epidural|Clinic, Pain
Interventions: PROCEDURE: Fluoroscopically guided lumbar medial branch nerve radiofrequency denervation.|PROCEDURE: Fluoroscopically guided lumbar medial branch nerve injection.|PROCEDURE: Fluoroscopically guided lumbar epidural corticosteroid injection.|PROCEDURE: Fluoroscopically guided caudal epidural corticosteroid injection.|PROCEDURE: Fluoroscopically guided pulsed radiofrequency of the lumbar dorsal root ganglion.|PROCEDURE: Fluoroscopically guided transforaminal epidural corticosteroid injection or lumbar selective root block.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of the Efficacy and Mechanisms of Change of Compassion Cultivation Training in Medical Students
Status: COMPLETED
Conditions: Stress|Depression|Anxiety|Burn Out|Well-being|Resilience|MIndfulness|Compassion|Self-Compassion|Empathy
Interventions: BEHAVIORAL: Compassion Cultivation Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Clinical Study of Taurine Combined With Neoadjuvant Chemo-Immunotherapy for Treatment of Locally Advanced Gastric Cancer
Status: RECRUITING
Conditions: Gastric Cancer
Interventions: DIETARY_SUPPLEMENT: Taurine|BIOLOGICAL: Serplulimab|DRUG: XELOX regimen|DRUG: FLOT regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Adding Azathioprine/Hydroxyurea Preconditioning to Alemtuzumab/TBI to Reduce Risk of Graft Failure in MSD HSCT in Adult SCD Patients
Status: RECRUITING
Conditions: Sickle Cell Disease
Interventions: OTHER: Preconditioning with azathiprine and hydroxyurea (3 months)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pilot Study of Whole Body Vibration for Children With Cerebral Palsy (CP) From 12 Months of Age
Status: COMPLETED
Conditions: Cerebral Palsy (CP)
Interventions: DEVICE: Galileo® tilt table for children
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Antiarrhythmic and Symptomatic Effect of ISIS CRP Rx Targeting CRP in Paroxysmal Atrial Fibrillation
Status: COMPLETED
Conditions: Paroxysmal Atrial Fibrillation
Interventions: DRUG: ISIS CRP Rx|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Supplementation of Fluoride on Maternal Periodontal Health, Preterm Delivery, and Perinatal Well-Being
Status: COMPLETED
Conditions: Preterm Birth|Preterm Labor|Bacteremia|Preterm Premature Rupture of Fetal Membranes
Interventions: DRUG: Prenatal vitamin-mineral containing 3 mg fluoride|DIETARY_SUPPLEMENT: Prenatal vitamin-mineral containing 0 mg fluoride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Fixed-schedule Benzodiazepine Dosing vs Based on a CIWA-Ar Alcohol Protocol in Alcohol Detoxification.
Status: COMPLETED
Conditions: Alcoholdependence|CIWA-R|Benzodiazepines
Interventions: OTHER: diazepam (or equivalence if other benzodiazepine)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pilot Study of a Text Message Platform to Reduce Risky Drinking in Young Adults
Status: COMPLETED
Conditions: Alcohol Abuse|Alcohol Consumption|Drinking Behavior
Interventions: BEHAVIORAL: Motivational and Normative Feedback|BEHAVIORAL: Self-Awareness
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Alpha Omega Trial: Study of Omega-3 Fatty Acids and Coronary Mortality
Status: COMPLETED
Conditions: Cardiovascular Diseases
Interventions: DIETARY_SUPPLEMENT: margarine spread
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study Looking at Kidney Function in Kidney Transplant Recipients Who Are Taking Anti-rejection Medication Including Tacrolimus and With or Without Sirolimus.
Status: COMPLETED
Conditions: Kidney Transplantation
Interventions: DRUG: Advagraf|DRUG: Mycophenolate Mofetil|DRUG: Sirolimus|DRUG: Corticosteroids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparison of the Angiographic Result of the Orsiro Hybrid Stent With Resolute Integrity Stent
Status: COMPLETED
Conditions: Coronary Artery Disease|Coronary Heart Disease|Stable Angina|Unstable Angina|ST-segment Elevation Myocardial Infarction|Non-ST-segment Elevation Myocardial Infarction
Interventions: DEVICE: Osiro Hybrid Drug-Eluting Stent|DEVICE: Resolute Integrity
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PET and CT Scans to Evaluate Patients With Stage III or Stage IV Melanoma
Status: COMPLETED
Conditions: Melanoma (Skin)
Interventions: DRUG: iodinated contrast dye|PROCEDURE: computed tomography|PROCEDURE: positron emission tomography|RADIATION: fludeoxyglucose F 18
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: DIAGNOSTIC
Clinical trial: A 52 Week Study to Evaluate the Effects of Losartan With or Without HCTZ on Plasma Glucose, Metabolic Parameters, Blood Pressure in Hypertensive Patients With Metabolic Syndrome (0954A-331)
Status: COMPLETED
Conditions: Hypertension|Metabolic Disorder
Interventions: DRUG: losartan potassium (+) hydrochlorothiazide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: McGrath Videolaryngoscopy and Direct Laryngoscopy Rapid Sequence Intubation
Status: RECRUITING
Conditions: Surgery
Interventions: OTHER: Conventional direct laryngoscopy using a Macintosh blade|DEVICE: McGrath videolaryngoscope for rapid sequence endotracheal intubation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: A Clinical Trial to Study the Effects of GRC 17536 in Patients With Painful Diabetic Neuropathy (Painful Extremities Due to Peripheral Nerve Damage in Diabetic Patients)
Status: WITHDRAWN
Conditions: Painful Diabetic Neuropathy
Interventions: DRUG: GRC 17536 (Medium Dose)|DRUG: GRC 17536 (Low Dose)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Patellar Resurfacing Versus Patellar Retention in Total Knee Arthroplasty - A Randomized Clinical Trial
Status: COMPLETED
Conditions: Total Knee Replacement
Interventions: DEVICE: Patellar Replacement Prosthesis|DEVICE: Profix TKR with Patellar Retention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Role of Endogenous GIP in Glycosis Metabolism During Fasting
Status: ENROLLING_BY_INVITATION
Conditions: Obesity
Interventions: BIOLOGICAL: GIP[3-30]NH2|OTHER: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of N-acetylcysteine as Add on Therapy With SSRI in Moderate to Severe OCD Patients
Status: UNKNOWN
Conditions: OCD
Interventions: DRUG: N-acetylcysteine tablet 600mg|DRUG: Placebo tablet 600mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: BLOOM Forward: Investigating Weight Loss Impact on TJAC Patients
Status: NOT_YET_RECRUITING
Conditions: Obesity|Knee Osteoarthritis|Hip Osteoarthritis|Arthroplasty Complications
Interventions: BEHAVIORAL: Building Lifestyle Options for Orthopedic Mobility (BLOOM)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radiation Therapy and Cisplatin With or Without Surgery in Treating Patients With Stage III-IV Oropharyngeal Cancer
Status: WITHDRAWN
Conditions: Stage III Squamous Cell Carcinoma of the Oropharynx|Stage IVA Squamous Cell Carcinoma of the Oropharynx|Tongue Cancer
Interventions: PROCEDURE: therapeutic conventional surgery|RADIATION: intensity-modulated radiation therapy|DRUG: cisplatin|PROCEDURE: quality-of-life assessment|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study of a Contact Lens With Ketotifen in Healthy, Normal Volunteers
Status: COMPLETED
Conditions: Allergic Conjunctivitis
Interventions: DEVICE: contact lens with ketotifen|DEVICE: contact lens
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bone Histomorphometry in Postmenopausal Men and Women With Osteoarthritis Undergoing Total Hip Replacement
Status: COMPLETED
Conditions: Osteoporosis
Interventions: OTHER: Tetracycline|OTHER: Demeclocycline|PROCEDURE: Total Hip Replacement
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Use of Ketamine vs Methohexital for Electroconvulsive Therapy (ECT) on Patient Recovery and Re-orientation Time
Status: COMPLETED
Conditions: Post-anesthesia Recovery|Orientation
Interventions: DRUG: Ketamine|DRUG: Methohexital
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Optimal Dosing of IC-Green for Visualization of Rotator Cuff Vascularity Using Advanced Imaging Modality Arthroscopy
Status: RECRUITING
Conditions: Rotator Cuff Tears
Interventions: DRUG: Indocyanine Green
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effects of a Short-term Exercise Intervention on Sleep in Women Exposed to Trauma: A Randomized Controlled Trial
Status: COMPLETED
Conditions: Traumatic Stress Disorder|Post Traumatic Stress Disorder|Trauma and Stressor Related Disorders|Mental Disorders|Exercise
Interventions: BEHAVIORAL: High Intensity Interval Training (HIIT)|OTHER: Waitlist
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Optimal Duration of Preoperative Anti-tuberculosis Treatment of Spinal Tuberculosis
Status: UNKNOWN
Conditions: Tuberculosis, Spinal
Interventions: DRUG: Isoniazid|DRUG: Rifampicin|DRUG: Ethambutol|DRUG: Pyrazinamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Left Ventricular Filling Pressures During Exercise
Status: COMPLETED
Conditions: Heart Failure With Preserved Ejection Fraction (HFPEF)|Left Ventricular End Diastolic Pressure (LVEDP)
Interventions: PROCEDURE: measure of left ventricular and diastolic pressure at exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: High Frequency Repetitive Transcranial Magnetic Stimulation (rTMS) in the Treatment of Post-traumatic Stress Disorder (PTSD)
Status: COMPLETED
Conditions: Post-Traumatic Stress Disorder
Interventions: DEVICE: Repetitive Transcranial Magnetic Stimulation (rTMS) (MagPro, Medtronic)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT