pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Aspirin Supplementation for Pregnancy Indicated Risk Reduction In Nulliparas (ASPIRIN)
Status: COMPLETED
Conditions: Premature Birth
Interventions: DRUG: Low dose aspirin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Genetic Alzheimer's Disease Mutation Carriers in Preclinical Stages of the Disease 18F-Florbetaben Positron Emission Tomography Study
Status: TERMINATED
Conditions: Alzheimer Disease
Interventions: RADIATION: Florbetaben
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Fed Study of Balsalazide Disodium Capsules 750 mg and Colazal® Capsules 750 mg
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BALSALAZIDE DISODIUM CAPSULES, 750 MG|DRUG: COLAZAL® Capsules 750 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: taVNS Cold Pressor
Status: COMPLETED
Conditions: taVNS|Brain Stimulation
Interventions: DEVICE: Active taVNS|DEVICE: Sham taVNS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Biobran/MGN-3 Increases Innate Resistance and Reduces the Incidence of Influenza-like Illnesses
Status: COMPLETED
Conditions: Influenza-like Illness
Interventions: DIETARY_SUPPLEMENT: Biobran/MGN-3|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: A Dose Response Trial to Evaluate Clinical and Mycological Effect of Nitric Oxide in Subjects With Tinea Pedis
Status: COMPLETED
Conditions: Tinea Pedis
Interventions: DRUG: 1% gaseous Nitric Oxide blended in Oxygen
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Gemigliptin on Metabolic Endotoxemia and Lipemia
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Gemigliptin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Repeated Neural Stem Cell Based Virotherapy for Newly Diagnosed High Grade Glioma
Status: NOT_YET_RECRUITING
Conditions: Glioma, Malignant|New Diagnosis Tumor
Interventions: BIOLOGICAL: NSC-CRAd-S-pk7|DIETARY_SUPPLEMENT: N-acetylcysteine amide (NACA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improving Women's Health by Using an Electronic Pelvic Floor Questionnaire
Status: COMPLETED
Conditions: Urinary Incontinence|Fecal Incontinence|Pelvic Floor Disorders
Interventions: OTHER: e-PAQ-PF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Robotic-Assisted da Vinci System Prophylactic Nipple-Sparing Mastectomy
Status: RECRUITING
Conditions: Nipple Sparing Mastectomy
Interventions: DEVICE: Nipple-Sparing Mastectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Efficacy of Two Models of Intensive Upper Limb Training on Quality of Life in Children With Congenital Hemiplegia
Status: COMPLETED
Conditions: Hemiplegia; Congenital
Interventions: OTHER: Modified Constraint-Induced Movement Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Preoperative Identification of the Histologically "Vulnerable" Plaque Using Non-invasive Imaging, Biomechanical Assessment and Baroreflex Evaluation in Patients With Severe Carotid Stenosis
Status: COMPLETED
Conditions: Carotid Artery Plaque|Diagnosis
Interventions: PROCEDURE: Carotid endarterectomy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Implementing FBT for Adolescent AN for Providers in Private Practice
Status: ACTIVE_NOT_RECRUITING
Conditions: Online Training for Therapists
Interventions: OTHER: Online FBT Training|OTHER: Webinar FBT Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Trial Comparing Metabolic Efficiency of Islet Graft to Intensive Insulin Therapy for Type 1 Diabetes's Treatment
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: BIOLOGICAL: Islet Graft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Anti-CD20 Antibodies (Rituximab Biosimilar) in the Treatment of Childhood Steroid-dependent Nephrotic Syndrome
Status: TERMINATED
Conditions: Nephrotic Syndrome Steroid-Dependent
Interventions: DRUG: Rituximab Biosimilar|DRUG: Mycophenolate Mofetil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Extension Study of RO5045337 in Participants Participating in Previous Roche-sponsored Cancer Studies
Status: COMPLETED
Conditions: Myelogenous Leukemia, Chronic, Neoplasms, Myelogenous Leukemia, Acute
Interventions: DRUG: RO5045337
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Percutaneous Peristyloid Glossopharyngeal Block After Tonsillectomy
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: PROCEDURE: glossopharyngeal nerve block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rifaximin Therapy vs Low FODMAP Diet In IBS
Status: RECRUITING
Conditions: Irritable Bowel Syndrome|Small Intestinal Bacterial Overgrowth
Interventions: DRUG: Rifaximin|OTHER: Low FODMAP diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Changes in Adaptive Immune Responses and Effector Cell Responses Upon Nasal Allergen Exposure - a Pilot Study
Status: COMPLETED
Conditions: Allergic Rhinitis|Allergic Inflammation
Interventions: DIAGNOSTIC_TEST: Nasal Provocation with Birch Extract|OTHER: Nasal Provocation with NaCl 0.9%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Spices for Cultivating a Healthy Gut Microbiome and Cardiometabolic Profile
Status: RECRUITING
Conditions: Cardiometabolic Syndrome
Interventions: OTHER: Yogurt with added Spices|OTHER: Yogurt without added Spices
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Saving Life and Limb: FES for the Elderly With PAD
Status: COMPLETED
Conditions: Peripheral Arterial Disease
Interventions: DEVICE: FES (Gait MyoElectric Stimulator)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Compassion Meditation and ReliefLink App for Suicidal, Low-Income, African Americans
Status: TERMINATED
Conditions: Suicidal Ideation
Interventions: BEHAVIORAL: Compassion meditation (CM)|BEHAVIORAL: Support group (SG)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A 30 Day Study to Evaluate Efficacy and Safety of Pre-hospital vs. In-hospital Initiation of Ticagrelor Therapy in STEMI Patients Planned for Percutaneous Coronary Intervention (PCI)
Status: COMPLETED
Conditions: Myocardial Infarction|Segment Elevation Myocardial Infarction (STEMI)
Interventions: DRUG: Ticagrelor|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Open-Label Study to Compare the Bleeding Profile of Norelgestromin/Ethinyl Estradiol in an Extended Regimen to Norelgestromin/Ethinyl Estradiol Given in a Traditional Regimen
Status: COMPLETED
Conditions: Metrorrhagia
Interventions: DRUG: norelgestromin/ethinyl estradiol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neurogenetic Pharmaceuticals (NGP) 555 in Healthy Young Volunteers (Single-ascending Dose)
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: NGP 555
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of HD-tDCS Assisted ECT for Depression Disorder
Status: RECRUITING
Conditions: Transcranial Direct Current Stimulation|Electroconvulsive Therapy|Depressive Disorder
Interventions: DEVICE: High definition transcranial direct current stimulation|DEVICE: Sham High definition transcranial direct current stimulation|DEVICE: electroconvulsive therapy device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 3 Study of Dienogest for the Treatment of Endometriosis in Chinese Patients
Status: COMPLETED
Conditions: Endometriosis
Interventions: DRUG: Dienogest (Visanne, BAY86-5258)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Can Investigators Reduce Urinary Catheter Use and Lower Urinary Tract Infection Among Women Undergoing Benign Gynecologic Surgery?
Status: COMPLETED
Conditions: Urinary Tract Infections|Urinary Retention|Satisfaction
Interventions: OTHER: Fast Track foley removal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Fasiglifam in Type 2 Diabetic Subjects With Chronic Kidney Disease Stage 4 or 5 on Hemodialysis
Status: WITHDRAWN
Conditions: Type 2 Diabetes Mellitus|Chronic Kidney Disease
Interventions: DRUG: Fasiglifam|DRUG: Placebo|DRUG: Antihyperglycemic therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bevacizumab Plus Paclitaxel Optimization Study With Interventional Aintenance Endocrine Therapy in Breast Cancer
Status: COMPLETED
Conditions: Metastatic Breast Cancer
Interventions: DRUG: Paclitaxel|DRUG: Bevacizumab|DRUG: Letrozole|DRUG: Anastrozole|DRUG: Exemestane|DRUG: Fulvestrant|DRUG: Goserelin|DRUG: leuprorelin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Study of Topical Vitamin C (THDA) Versus Topical Vitamin C (THDA) With Acetyl Zingerone
Status: ACTIVE_NOT_RECRUITING
Conditions: Wrinkle|Skin Pigmentation
Interventions: OTHER: THDA + Acetyl Zingerone Topical Product|OTHER: THDA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Global Self-management Telematic Support for Patients With Obstructive Sleep Apnea.
Status: COMPLETED
Conditions: Obstructive Sleep Apnea|Telemedicine|Compliance, Patient
Interventions: BEHAVIORAL: Telematic control and self-management program|BEHAVIORAL: Habitual follow-up in Healthcare System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Healing Touch in Treating Patients Receiving Chemotherapy for Acute Myeloid Leukemia or Acute Lymphocytic Leukemia
Status: COMPLETED
Conditions: Fatigue|Leukemia|Psychosocial Effects of Cancer and Its Treatment
Interventions: PROCEDURE: therapeutic touch
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Afatinib in Patients With Non Small Cell Lung Cancer (NSCLC) With Epidermal Growth Factor Receptor (EGFR) Mutations
Status: COMPLETED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: Afatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Quick Large Balloon Dilatation for Removal of Large Bile Duct Stones (SHODBADI)
Status: RECRUITING
Conditions: Pancreatitis, Acute|Bleeding|Cholangitis
Interventions: DEVICE: endoscopic short duration papillary large balloon dilation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I/Ib, Multicenter, Open-Label, Dose Escalation Study of E7080 in Patients With Solid Tumors and in Combination With Temozolomide in Patients With Advanced and/or Metastatic Melanoma
Status: COMPLETED
Conditions: Metastatic Melanoma
Interventions: DRUG: E7080
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Staccato Alprazolam Abuse Liability
Status: COMPLETED
Conditions: Abuse Liability of Staccato Alprazolam
Interventions: DRUG: Inhaled placebo + oral placebo|DRUG: Inhaled alprazolam 0.5 mg|DRUG: Inhaled alprazolam 1 mg|DRUG: Inhaled alprazolam 2 mg|DRUG: Oral alprazolam 1 mg|DRUG: Oral alprazolam 2 mg|DRUG: Oral alprazolam 4 m|DRUG: Oral alprazolam 2 mg qualifying session|DRUG: Oral placebo qualifying session
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ACCUvein Measure Before ULtrasound as A facilitataTION Tool for Venous Marking
Status: COMPLETED
Conditions: Other Diseases of Veins and Lymphatics
Interventions: DEVICE: ACCUVEIN plus ultrasound|DEVICE: Ultrasound only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety of Autologous Cord Blood Cells in HLHS Patients During Norwood Heart Surgery
Status: COMPLETED
Conditions: Hypoplastic Left Heart Syndrome|Heart Defects, Congenital|Pediatric Disorder
Interventions: BIOLOGICAL: Autologous Human Placental Cord Blood Mononuclear Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect on Wound Healing of Vigamox Versus Cravit
Status: COMPLETED
Conditions: Cataract Extraction
Interventions: DRUG: Moxifloxacin 0.5% ophthalmic solution (Vigamox)|DRUG: Levofloxacin 0.5% ophthalmic solution (Cravit)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of BIA Monitoring of Brain Edema on the Neurological Prognosis of Supratentorial Massive ICH
Status: UNKNOWN
Conditions: Cerebral Hemorrhage, Hypertensive|Bioelectrical Impedance Analysis|Intracranial Hypertension|Monitoring|Critical Care|Treatment Outcome
Interventions: DEVICE: Non-invasive intracranial pressure monitoring|OTHER: Parenchymal Intracranial pressure monitor|OTHER: Treatment based on clinical and imaging observations
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Comparing the Efficacy and Safety of ABT-874 to Etanercept and Placebo in Subjects With Moderate to Severe Chronic Plaque Psoriasis
Status: COMPLETED
Conditions: Moderate to Severe Plaque Psoriasis
Interventions: BIOLOGICAL: ABT-874|BIOLOGICAL: etanercept|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Investigating the Structural and Functional Changes to the Retina Following PRP in Diabetic Retinopathy Patients
Status: COMPLETED
Conditions: Diabetic Retinopathy
Interventions: DEVICE: Pan-Retinal Photocoagulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Correlation of Intra-abdominal Pressure With Gastric and Urinary Bladder Pressures in Patients With Morbid Obesity
Status: COMPLETED
Conditions: Morbid Obesity|Intra-Abdominal Hypertension|Bariatric Surgery Candidate
Interventions: DIAGNOSTIC_TEST: measuring IAP and respiratory parameters
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Ropivacaine Versus Bupivacaine for Spinal Anaesthesia in Patients Undergoing Unilateral Lower Limb Surgery
Status: COMPLETED
Conditions: Anesthesia,Spinal
Interventions: DRUG: Ropivacaine|DRUG: Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Study to Compare the Safety and Efficacy of ALZ-1101 to Latanoprost in Patients With Intraocular Pressure Inadequately Controlled by Latanoprost
Status: COMPLETED
Conditions: Primary Open Angle Glaucoma|Ocular Hypertension|Elevated Intraocular Pressure
Interventions: DRUG: ALZ-1101|DRUG: Latanoprost
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tislelizumab in Participants With Relapsed or Refractory Classical Hodgkin Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Classical Hodgkin Lymphoma
Interventions: DRUG: Tislelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Single Vaccination of an Adenovirus Serotype 26 Pre-Fusion F (Ad26.preF) Based Respiratory Syncytial Virus (RSV) Vaccine in Japanese Adults Aged 60 Years and Older
Status: COMPLETED
Conditions: Healthy
Interventions: BIOLOGICAL: RSV Vaccine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: SBRT in Combination With Sintilimab and GM-CSF for the Treatment of Advanced NSCLC
Status: UNKNOWN
Conditions: NSCLC Stage IV
Interventions: DRUG: GM-CSF|DRUG: Sintilimab|RADIATION: SBRT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of ABT-378/Ritonavir Combination in HIV-Infected Patients Who Have Taken Protease Inhibitors
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Lopinavir/Ritonavir|DRUG: Nevirapine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Understanding and Testing Recovery Processes for PTSD and Alcohol Use Following Sexual Assault
Status: RECRUITING
Conditions: Alcohol; Use, Problem|Posttraumatic Stress Disorder
Interventions: BEHAVIORAL: Imaginal Exposure|BEHAVIORAL: Alcohol Skills Training|BEHAVIORAL: Supportive Telehealth
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Zoledronic Acid in Acute Spinal Cord Injury: Prevention of Bone Loss
Status: TERMINATED
Conditions: Bone Loss
Interventions: DRUG: zoledronic acid|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pharmacodynamics of Omiganan (CLS001) in Patients With Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: CLS001|DRUG: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: STATE Trial: SusTained Attention Training to Enhance Sleep - Remote
Status: COMPLETED
Conditions: Insomnia Chronic
Interventions: OTHER: Computerized Plasticity-Based Adaptive Cognitive Training|OTHER: Active Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Early Discharged Lumbar Spine Fusion Reduced Postoperative Readmissions: A Follow-up Study in a National Cohort
Status: COMPLETED
Conditions: Lumbar Spinal Fusion|Early Discharge|Readmission
Interventions: BEHAVIORAL: Rates of readmission and reoperation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Single Instillation of Three Different Topical Lubricants on Tear Film Thickness in Patients With Dry Eye Syndrome
Status: COMPLETED
Conditions: Dry Eye Syndromes
Interventions: DEVICE: Neovis Total Multi® Eye Drops|DEVICE: Vismed Multi® Eye Drops|DEVICE: Hydrabak® Eye Drops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Botulinum Toxin Injection in Patients Undergoing Hemorrhoidectomy-A Prospective, Randomized Study
Status: UNKNOWN
Conditions: The Influence of Timing of Botulinum Toxin Injection on Postoperative Pain Control
Interventions: BIOLOGICAL: botulinum toxin type A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Plant Sterols Esterified to Fish Oil Fatty Acids on Plasma Lipid Levels
Status: COMPLETED
Conditions: Dyslipidemia
Interventions: DIETARY_SUPPLEMENT: Plant sterols esters|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Trunk Stabilization Exercises on Quality of Life and Communication in Cerebral Palsy
Status: COMPLETED
Conditions: Cerebral Palsy
Interventions: OTHER: Neurodevelopmental treatment (NDT)|OTHER: Feeding and oral-motor intervention strategies|OTHER: Neck and trunk stabilization exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Preemptive Analgesia in Cruciate Reconstruction
Status: COMPLETED
Conditions: Anterior Cruciate Ligament Injury
Interventions: DRUG: Celecoxib|DRUG: etoricoxib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Oral ABBV-932 Capsules to Evaluate Dopamine D2 and D3 Receptor Occupancy in Brain in Adult Healthy Volunteers
Status: NOT_YET_RECRUITING
Conditions: Healthy Volunteers
Interventions: DRUG: ABBV-932
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Cross-Over Study to Evaluate Lung Function Response After Treatment With Umeclidinium (UMEC) 62.5 Micrograms (mcg), Vilanterol (VI) 25 mcg, and Umeclidinium/Vilanterol (UMEC/VI) 62.5/25 mcg Once-Daily in Subjects With Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DEVICE: Umeclidinium 62.5 mcg|DEVICE: Vilanterol 25 mcg|DEVICE: Umeclidinium/Vilanterol 62.5/25 mcg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Olaparib & Radiation Therapy for Patients Triple Negative Breast Cancer (TNBC)
Status: COMPLETED
Conditions: Breast Neoplasms, Triple-Negative|Breast Neoplasm Malignant Female|Radiotherapy Side Effect
Interventions: DRUG: Olaparib|RADIATION: Radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dry Needling in Subjects With Delayed Onset Muscle Soreness
Status: COMPLETED
Conditions: Delayed Onset Muscle Soreness
Interventions: OTHER: Dry needling|OTHER: Sham needling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Evaluation of the "Treatment Group Model for Abused Women" in Shelters in Hong Kong
Status: COMPLETED
Conditions: Abused Women
Interventions: BEHAVIORAL: self-esteem enhancement group|BEHAVIORAL: Standard care for abused women
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility of FMISO in Brain Tumors
Status: RECRUITING
Conditions: Malignant Brain Neoplasm
Interventions: DRUG: ¹⁸F-Fluoromisonidazole|PROCEDURE: Computed Tomography|PROCEDURE: Magnetic Resonance Imaging|PROCEDURE: Positron Emission Tomography|PROCEDURE: Oxygen Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Programmed Cell Death Protein-1 (PD-1) Monoclonal Antibody for EBV-HLH and CAEBV as First-line Therapy
Status: UNKNOWN
Conditions: EBV Infection
Interventions: DRUG: PD-1 monoclonal antibody
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Decisional Conflicts, Health-related QoL and Satisfaction With Care in High-risk cSCC in the Head-neck Region
Status: RECRUITING
Conditions: Cutaneous Squamous Cell Carcinoma|Cutaneous Squamous Cell Carcinoma of the Head and Neck|Squamous Cell Carcinomas|Squamous Cell Carcinoma of Head and Neck|Squamous Cell Carcinoma of the Skin|Squamous Cell Carcinoma of the Head and Neck|Skin Cancer|High-Risk Cancer|Quality of Life|Satisfaction, Patient
Interventions: OTHER: Regular care with additionally administration of questionnaires
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Chlorthalidone in Chronic Kidney Disease
Status: COMPLETED
Conditions: Renal Insufficiency, Chronic|Hypertension
Interventions: DRUG: Chlorthalidone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Dexmedetomidine on the Characteristics of High Volume/Low Concentration Ropivacaine in a Caudal Block in Pediatrics
Status: COMPLETED
Conditions: Ambulatory Orchipexy
Interventions: DRUG: Caudal ropivacaine + normal saline|DRUG: Caudal ropivacaine + dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of the Glucodynamic Effects of Dulaglutide (LY2189265) in Japanese Participants With Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: Dulaglutide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Transurethral Prostate Enucleation in Surveillance Protocol for Low Risk Prostate Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Cancer Stage I|Bladder Outlet Obstruction
Interventions: PROCEDURE: Anatomical Endoscpic enucleation of the Prostate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cabazitaxel at 20 mg/m² Compared to 25 mg/m² With Prednisone for the Treatment of Metastatic Castration Resistant Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: Cabazitaxel (XRP6258)|DRUG: Prednisone (or Prednisolone)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Study Between Patellar Denervation and Non-patellar Denervation in Total Knee Arthroplasty With Patellar Resurfacing
Status: COMPLETED
Conditions: Patellar Denervation|Non-patellar Denervation|Patellar Resurfacing
Interventions: PROCEDURE: Total knee arthroplasty|PROCEDURE: Patellar denervation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intergroup Randomized Trial for Children or Adolescents With B-Cell Non Hodgkin Lymphoma or B-Acute Leukemia: Rituximab Evaluation in High Risk Patients
Status: UNKNOWN
Conditions: B-cell Non Hodgkin Lymphoma|Mature B-cell Leukemia Burkitt-type
Interventions: DRUG: Vincristine, cyclophosphamide, methotrexate, doxorubicin, cytarabine, ara-C|DRUG: Rituximab, Vincristine, cyclophosphamide, methotrexate, doxorubicin, cytarabine, ara-C
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Triglycerides on Age-Related Cognitive Function Decline in Older Subjects
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: GSK2981710|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Tomosynthesis of Pathologies of the Chest and Skeletal Structures in Comparison to CT
Status: TERMINATED
Conditions: Lung Disease|Wrist Fracture
Interventions: OTHER: Tomosythesis scan of the lung or the wrist|OTHER: CT scan of the lung or the wrist|OTHER: conventional X-ray of the lung or the wrist
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Dose-finding Study for the Ultralow-dose Levonorgestrel Intrauterine Contraceptive System (LCS)
Status: COMPLETED
Conditions: Contraception
Interventions: DRUG: Levonorgestrel IUS (BAY86-5028, G04209B)|DRUG: Levonorgestrel IUS (BAY86-5028, G04209C)|DRUG: Levonorgestrel IUS (Mirena, BAY86-5028)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Interaction Study of Ibrutinib and Cytochrome P450 (CYP) 3A Inhibitors in Participants With B-cell Malignancy
Status: COMPLETED
Conditions: B-Cell Chronic Lymphocytic Leukemia
Interventions: DRUG: Ibrutinib|DRUG: Erythromycin|DRUG: Voriconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE) Could Decrease the Incidence of Oxygen Desaturation During Suspension Laryngoscopy: a Randomized Controlled Trial (Optilaryngo)
Status: COMPLETED
Conditions: Apnea, Postanesthetic|Desaturation of Blood|Apnea|Anesthesia|Larynx Disease|Pharynx; Anomaly
Interventions: DEVICE: optiflow
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MRI Risk Maps for Prostate Cancer Diagnosis Using Targeted Biopsy
Status: RECRUITING
Conditions: Prostate Cancer|Prostate Adenocarcinoma|Prostate Neoplasm
Interventions: OTHER: Risk Map Decision Support System (DSS).|RADIATION: Magnetic Resonance Imaging (MRI)|PROCEDURE: Magnetic Resonance Imaging (MRI) Guided Biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Diet, Imaging and Energy Balance Trial (DIET)
Status: COMPLETED
Conditions: Obesity
Interventions: BEHAVIORAL: Low Carbohydrate Ketogenic Diet (LCKD)|BEHAVIORAL: Low Fat Diet (LFD)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Liposomal Bupivacaine Plus Bupivacaine Peripheral Nerve Blockade Versus Ropivacaine Plus Dexamethasone Peripheral Nerve Blockade for Arthroscopic Rotator Cuff Repair
Status: COMPLETED
Conditions: Rotator Cuff Tears|Shoulder Pain
Interventions: DRUG: Liposomal bupivacaine|DRUG: Bupivacaine Hcl 0.5% Inj|DRUG: Ropivacaine 0.5% Injectable Solution|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Supermarket and Web-Based Intervention Targeting Nutrition (SuperWIN) for Cardiovascular Risk Reduction
Status: COMPLETED
Conditions: Obesity|Hypertension|Hyperlipidemias|Diet Modification
Interventions: OTHER: In-store POP education|OTHER: Online POP education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Camrelizumab Plus Apatinib as Adjuvant Therapy in Patients With Hepatocellular Carcinoma at High Risk of Recurrence After Radical Resection or Ablation
Status: NOT_YET_RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Camrelizumab|DRUG: Apatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of ADG106 In Combination With PD-1 Antibody In Advanced or Metastatic Solid Tumors and/or Non Hodgkin Lymphoma
Status: TERMINATED
Conditions: Solid Tumor|Non Hodgkin Lymphoma
Interventions: BIOLOGICAL: ADG106 injection|BIOLOGICAL: PD-1 antibody injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Safety, Pharmacokinetics, and Preliminary Anti-tumor Activity of RO7444973 in Participants With Unresectable and/or Metastatic MAGE-A4-positive Solid Tumors
Status: TERMINATED
Conditions: Solid Tumors
Interventions: DRUG: RO7444973|DRUG: Tocilizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Motor Image Training on Balance Performance in Geriatric Individuals
Status: RECRUITING
Conditions: Imagery (Psychotherapy)|Postural Control|Postural Balance|Virtual Reality Therapy|Surface Electromyography|Geriatric Assessment|Physical Therapy Techniques|Physical Therapy|Healthy Ageing|Healthy Aging|Falling
Interventions: OTHER: Balance Training|OTHER: Motor İmagery Training|OTHER: Action Observation Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study to Compare MAR-CUTIS With Dermabond Advanced
Status: TERMINATED
Conditions: Wounds and Injuries|Lacerations|Surgical Incision
Interventions: DEVICE: MAR-CUTIS|DEVICE: Dermabond Advanced
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non-operative Treatment in First-time Patellar Dislocation
Status: RECRUITING
Conditions: Patellar Dislocation
Interventions: OTHER: Standard care|OTHER: Taping|DEVICE: Sham taping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transabdominal Plane (TAP) Blocks for Inguinal Hernia Repairs
Status: COMPLETED
Conditions: Inguinal Hernia
Interventions: DRUG: 0.25% Bupivacaine|DRUG: Placebo|PROCEDURE: TAP block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Bioequivalence Study Using Clinical Endpoint for Diclofenac Sodium Gel 1% in Osteoarthritis Knee"
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: DRUG: Diclofenac sodium gel 1%|DRUG: Voltaren® Gel (Diclofenac Sodium Topical Gel) 1%|DRUG: Placebo gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hypoferritinemia Without Anemia Among Reproductive Age Females
Status: ACTIVE_NOT_RECRUITING
Conditions: Hypoferritenemia Without Anemia (HWA)|Iron Deficiency Without Anemia)
Interventions: DRUG: Iron III Hydroxide Polymaltose Complex eq. to Elemental Iron, 100 mg|DRUG: Ferric Carboxymaltose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BIP CVC Clinical Safety and Performance Study
Status: COMPLETED
Conditions: Surgery|Central Line Associated Blood Stream Infections (CLABSI)
Interventions: DEVICE: BIP CVC|DEVICE: Uncoated Standard CVC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effectiveness of Proactive Telephone Support Provided to Breastfeeding Mothers of Preterm Infants
Status: COMPLETED
Conditions: Breastfeeding|Quality of Life|Parental Stress|Attachment
Interventions: BEHAVIORAL: Person-centred proactive breastfeeding telephone support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Window of Opportunity Study of Preoperative Immunotherapy With Atezolizumab in Local SCCHN
Status: COMPLETED
Conditions: Squamous Cell Carcinoma of Head and Neck
Interventions: DRUG: Atezolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Fecal Microbiota Transplantation (FMT) in Severe IBS Patients
Status: NOT_YET_RECRUITING
Conditions: Irritable Bowel Syndrome
Interventions: DRUG: Administration of fecal microbiota transplantation ( FMT capsules)|DRUG: Administration of the sham (PLACEBO)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Personalized Radiotherapy for Biochemical Recurrence of Prostate Cancer After Prostatectomy.
Status: RECRUITING
Conditions: Prostate Cancer
Interventions: RADIATION: Radiation to the prostate bed with or without addition of radiation of lymph node irradiation.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Hypoxic Conditioning on Cerebrovascular Health in the Elderly
Status: RECRUITING
Conditions: Hypoxia|Cerebral Hypoxia|Brain Diseases|Exercise|Aging|Cognitive Decline|Healthy Aging
Interventions: PROCEDURE: Hypoxia and/or Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Hu-Mik-beta1 to Treat T-Cell Large Granular Lymphocytic Leukemia
Status: COMPLETED
Conditions: T-Cell Large Granular Lymphocytic Leukemia|Leukemia, T-Cell Large Granular Lymphocytic
Interventions: BIOLOGICAL: Hu-MiK-Beta-1
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacotherapy in Conjunction With Lifestyle Counseling for Management of Weight Regain After Bariatric Surgery
Status: RECRUITING
Conditions: Obesity
Interventions: DRUG: Topiramate|DRUG: Phentermine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized Placebo-Controlled Study of Lovastatin in Children With Neurofibromatosis Type 1
Status: COMPLETED
Conditions: Neurofibromatosis Type 1
Interventions: DRUG: Lovastatin ™|DEVICE: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Exploratory Efficacy Study of Collagen Membrane With Mesenchymal Stem Cells in the Treatment of Skin Defects
Status: UNKNOWN
Conditions: Wounds|Diabetic Foot Ulcers|Burns
Interventions: DEVICE: Medical Collagen Membrane with MSC|DEVICE: Medical Collagen Membrane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Impact of Insulin Therapy on Protein Turnover in Pre-Diabetic Cystic Fibrosis Patients
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: novolog insulin|DRUG: levemir insulin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability of Novel Medical Nutrition Products for NAFLD Treatment
Status: UNKNOWN
Conditions: NAFLD|NASH - Nonalcoholic Steatohepatitis
Interventions: DIETARY_SUPPLEMENT: Specialized product for medical nutrition (SPP-1)|BEHAVIORAL: individualized diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Influence of Treatment for Patent Ductus Arteriosus on Cerebral Oxygenation in Preterm Infants
Status: COMPLETED
Conditions: Prematurity of Fetus|Patent Ductus Arteriosus
Interventions: DRUG: Indomethacin|PROCEDURE: Surgical Ligation|DRUG: Ibuprofen
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Inflammatory Pathogenesis of Coronary Atherosclerosis in HIV
Status: COMPLETED
Conditions: Coronary Artery Disease|Human Immunodeficiency Virus
Interventions: DRUG: Colchicine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Matching Patients With Hematologic Malignancy to Adequate Clinical Trials
Status: UNKNOWN
Conditions: Hematologic Malignancies
Interventions: OTHER: Matching on the basis of molecular analysis|OTHER: Matching on the basis of physician's choice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Glucocorticoids With Antihistamines Versus Antihistamines in Acute Urticaria in Emergency
Status: COMPLETED
Conditions: Acute Urticaria
Interventions: DRUG: placebo|DRUG: prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study for the Treatment of Mania Associated With Bipolar I Disorder in Children and Adolescents
Status: COMPLETED
Conditions: Bipolar I Disorder
Interventions: DRUG: Divalproex Sodium (Depakote ER)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Role of Capsular Tension Ring (CTR) in Anterior Capsular Contraction
Status: COMPLETED
Conditions: Retinitis Pigmentosa|Cataract
Interventions: PROCEDURE: IOL surgery|PROCEDURE: IOL surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Imaging vs. no Testing in Asymptomatic High-risk Diabetic Patients
Status: UNKNOWN
Conditions: Asymptomatic|High Risk|Diabetes
Interventions: DIAGNOSTIC_TEST: Echocardiography|DIAGNOSTIC_TEST: CT angiography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: the Effect of Vitamin B 1 on Menstrual Pattern After Insertion of the IUD.
Status: NOT_YET_RECRUITING
Conditions: Intra-uterine Device Complication
Interventions: DRUG: VITAMIN B1 500mg|DEVICE: intra-uterine contraceptive device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Acne Keloidalis Nuchae (Razor Bumps Behind the Neck) Using UV Light Therapy
Status: COMPLETED
Conditions: Acne Keloidalis Nuchae
Interventions: RADIATION: Targeted UV-B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dose-Escalation Study to Assess the Safety, Tolerability, and Pharmacokinetics of Donepezil From Single Dose of GB-5001 IM Depot and Aricept® Oral Tablets in Healthy Male Volunteers
Status: COMPLETED
Conditions: Alzheimer Disease
Interventions: DRUG: GB-5001|DRUG: Placebo|DRUG: Oral cohort
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Determine the Effects of an Investigational Malaria Vaccine Given to Adults Living in the United States and Thereafter to Adults Living in Kenya
Status: COMPLETED
Conditions: Malaria
Interventions: BIOLOGICAL: Plasmodium falciparum Malaria Protein 010 (FMP010)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Gradual Versus Abrupt Reperfusion in Primary PCI (GUARD)
Status: COMPLETED
Conditions: ST-elevation Acute Myocardial Infarction
Interventions: DEVICE: deferred coronary stenting|DEVICE: immediate stenting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT