pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Gastric Volumetry by Gastric Tomodensitometry With Gas
Status: COMPLETED
Conditions: Morbid Obesity
Interventions: DEVICE: gastric tomodensitometry with gas at 3 months and 12 months
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Preoxygenation With High-flow Nasal Oxygen in Adult Trauma Patients During Rapid Sequence Induction Anaesthesia
Status: COMPLETED
Conditions: Anesthesia|Hypoxia|Trauma|Rapid Sequence Induction
Interventions: DEVICE: Tight Fitting Facemask|DEVICE: High Flow Nasal Oxygen (HFNO)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Ambrisentan in Single Ventricle
Status: COMPLETED
Conditions: Hypoplastic Left Heart Syndrome|Hypoplastic Right-sided Heart Complex
Interventions: DRUG: Ambrisentan|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects Of Adjuvants to Caudal Anesthesia on Hemodynamics Measured By Electrical Cardiometry In Children
Status: COMPLETED
Conditions: Caudal Block
Interventions: DRUG: Caudal block with dexmedetomedine|DRUG: Caudal dexamethasone|DRUG: Control (bupivacaine)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: New Stage 1 Formula on Gut Comfort and Gut Health
Status: COMPLETED
Conditions: Health Behavior
Interventions: DIETARY_SUPPLEMENT: Oral intake of Feihe New Formula|DIETARY_SUPPLEMENT: Oral intake of Feihe Stage 1 Formula|DIETARY_SUPPLEMENT: Breast Feeding
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Electronic Frailty Index (eFI)Cacious-Diabetes Care
Status: ACTIVE_NOT_RECRUITING
Conditions: Diabetes|Type2 Diabetes
Interventions: BEHAVIORAL: Pharmacist-Led Optimization Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Ph I Study of Lithium During Whole Brain Radiotherapy For Patients With Brain Metastases
Status: TERMINATED
Conditions: Brain and Central Nervous System Tumors|Cognitive/Functional Effects|Neurotoxicity|Solid Tumor
Interventions: DRUG: lithium carbonate|PROCEDURE: cognitive assessment|PROCEDURE: quality-of-life assessment|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Feasibility Study of the DragonFire for Hypertrophic Obstructive Cardiomyopathy
Status: NOT_YET_RECRUITING
Conditions: Obstructive Hypertrophic Cardiomyopathy
Interventions: DEVICE: DragonFire Transcatheter Myocardial Radiofrequency Ablation System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High-dose Intravenous Vitamin C (HDIVC) as Adjuvant Therapy in Critical Patients With Positive COVID-19. A Pilot Randomized Controlled Dose-comparison Trial.
Status: UNKNOWN
Conditions: Covid19
Interventions: DRUG: High doses of intravenous vitamin C|DRUG: Dextrose 500 mL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Benefits and Safety of Combined Polynucleotides and Hyaluronic Acid - Newest - for Acne Scars Treatment
Status: RECRUITING
Conditions: Atrophic Scar
Interventions: DEVICE: Subjects treated with Newest medical device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multi-center Trial of Single-Branched Stent Graft System to Treat Aortic Dissection
Status: UNKNOWN
Conditions: Distal Aortic Dissection
Interventions: DEVICE: Castor Stent Graft
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vascular Inflammation ReDuction and Perivascular Fat Imaging by Computed Tomography
Status: RECRUITING
Conditions: Coronary Artery Disease|Atheroscleroses, Coronary|Vascular Inflammation
Interventions: DEVICE: CaRi-Heart device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effectiveness of Stress Self-management Health Education Based on IMB Theory Among Nursing Students
Status: NOT_YET_RECRUITING
Conditions: Psychological Stress|Nursing Students
Interventions: BEHAVIORAL: IMB stress self-management health education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of the Administration of Levosimendan and Placebo in the Preparation of Critical Patients for Heart Surgery
Status: COMPLETED
Conditions: Cardiac Surgery
Interventions: DRUG: Levosimendan|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Safety of Gadovist in Renally Impaired Patients
Status: COMPLETED
Conditions: Fibrosis|Renal Impairment
Interventions: DRUG: Gadobutrol (Gadovist, BAY86-4875)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Does Psilocybin Require Psychedelic Effects to Treat Depression?
Status: RECRUITING
Conditions: Treatment-resistant Depression
Interventions: DRUG: Psilocybin 25 mg|DRUG: Risperidone 1 MG|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Ropinirole and Gabapentin for the Treatment of RLS in Patients on Maintenance HD
Status: TERMINATED
Conditions: Restless Legs Syndrome|End Stage Renal Disease
Interventions: DRUG: Ropinirole|DRUG: Gabapentin|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Effect of Electroacupuncture Combined With Paclitaxel Clinical Efficacy of Patients With Recurrence of High-grade Glioma
Status: RECRUITING
Conditions: Glioma
Interventions: DRUG: Temozolomide（TMZ） injection or oral administration|DRUG: Albumin-Bound Paclitaxel(ABX) intravenous drip|DEVICE: Specific mode electroacupuncture stimulation(SMES) intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Physiological Ventricular Pacing Vs Managed Ventricular Pacing for Persistent AF Prevention in Prolonged AV Interval
Status: RECRUITING
Conditions: Sinus Node Disease|Atrioventricular; Block, Second Degree (Types I and II)
Interventions: DEVICE: PhysioVP|DEVICE: DDD-VPA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Are Patients Suffering From DSPS Show Compromising in Everyday Functions and Abilities Before Handling the Disorder?
Status: UNKNOWN
Conditions: Delayed Sleep Phase Syndrome
Interventions: OTHER: Melatonin and light therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Seven Trial: Exploiting the Unfolded Protein Response
Status: NOT_YET_RECRUITING
Conditions: Pancreatic Cancer Metastatic|Pancreatic Adenocarcinoma Metastatic
Interventions: DRUG: Botensilimab|DRUG: Balstilimab|DRUG: Chloroquine Phosphate|DRUG: Celecoxib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: OraVescent Fentanyl (OVF) for the Treatment of Breakthrough Pain in Opioid Tolerant Cancer Patients
Status: COMPLETED
Conditions: Pain|Cancer
Interventions: DRUG: OraVescent fentanyl citrate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Vidaza (Azacitidine) Versus Support Treatment in Patients With Low Risk Myelodysplastic Syndrome (Low and Intermediate-1 IPSS) Without the 5q Deletion and Transfusion Dependent Anaemia
Status: COMPLETED
Conditions: Myelodysplastic Syndrome (MDS)
Interventions: DRUG: Azacitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PROSPECT - Profiling of Resistance Patterns & Oncogenic Signaling Pathways in Evaluation of Cancers of the Thorax and Therapeutic Target Identification
Status: RECRUITING
Conditions: Lung Cancer|Cancer of Thorax
Interventions: OTHER: Group Specific Aim 1|OTHER: Group Specific Aim 2|OTHER: Group Specific Aim 3|OTHER: Group Specific Aim 4|OTHER: Group Specific Aim 5|OTHER: Group Specific Aim 6
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Abscopal Effect for Metastatic Small Cell Lung Cancer
Status: WITHDRAWN
Conditions: Small Cell Lung Cancer|Radiotherapy|Thymalfasin
Interventions: RADIATION: Radiotherapy|DRUG: Thymalfasin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Ibrutinib in Subjects With Acute Myeloid Leukemia
Status: TERMINATED
Conditions: Acute Myeloid Leukemia (AML)
Interventions: DRUG: Ibrutinib|DRUG: Ibrutinib + LD-AraC|DRUG: Ibrutinib+Azacitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of the Pre-phonatory Inspiratory Volume on the Speech Quality of Neuromuscular Patients Dependent on Non-invasive Ventilation
Status: UNKNOWN
Conditions: Neuromuscular Diseases|Non Invasive Ventilation
Interventions: OTHER: speech trial
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: PROSPER: PostpaRtum PrOphylaxiS for PE Randomized Control Trial Pilot
Status: COMPLETED
Conditions: Venous Thromboembolism|Postpartum
Interventions: DRUG: Dalteparin Sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy of the InterX 5000 in the Treatment of Chronic Neck Pain
Status: COMPLETED
Conditions: Neck Pain|Shoulder Pain
Interventions: DEVICE: InterX 5000|DEVICE: InterX 5000
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Electronic LogMar Visual Acuity and Contrast Sensitivity in a Population of Contact Lens Wearers
Status: COMPLETED
Conditions: Visual Acuity
Interventions: DEVICE: senofilcon A|DEVICE: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of MOVI Interventions on Adiposity, Cognition and Subclinical Atherosclerosis: MOVI-daFit!
Status: COMPLETED
Conditions: Physical Activity|Obesity|Children|Cardiovascular|Cardiorespiratory Fitness
Interventions: BEHAVIORAL: MOVI intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparison of Routine IM Influenza Immunization and Administration by Jet-injector (Med-Jet H4™) in Healthy Young Adults
Status: COMPLETED
Conditions: Needle Phobia
Interventions: BIOLOGICAL: Fluviral influenza vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Rule Out of ACS in Primary Care Using a Decision Rule for Chest Pain Including Hs-troponin I POCT
Status: ACTIVE_NOT_RECRUITING
Conditions: Chest Pain|Myocardial Infarction|Acute Coronary Syndrome
Interventions: DIAGNOSTIC_TEST: Clinical decision rule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy and Safety Study to Evaluate MT-6548 in Hemodialysis Subjects Currently Receiving ESAs With Anemia Associated With Chronic Kidney Disease in Japan
Status: COMPLETED
Conditions: Anemia; Hemodialysis Dependent Chronic Kidney Disease
Interventions: DRUG: MT-6548|DRUG: Darbepoetin alfa|DRUG: MT-6548-matching placebo|DRUG: Darbepoetin alfa-matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Combination Chemotherapy Regimens in Treating Patients With Extensive-Stage Small Cell Lung Cancer
Status: COMPLETED
Conditions: Extensive Stage Small Cell Lung Cancer
Interventions: BIOLOGICAL: G-CSF|DRUG: Cisplatin|DRUG: Etoposide|DRUG: Irinotecan|DRUG: Topotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prostate MRI and Pylarify PSMA PET/CT
Status: NOT_YET_RECRUITING
Conditions: Prostate Cancer
Interventions: DRUG: Pylarify Piflufolastat Flourine-18 (18F-DCFPyL)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of 25% Trichloroacetic Acid Peel Versus 30% Salicylic Acid Peel in Mild to Moderate Acne Vulgaris
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: 25% TRICHLOROACETIC ACID|DRUG: 30% salicylic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clomiphene Citrate, Estradiol and Sildenafil for Induction of Ovulation in Unexplained Infertility
Status: COMPLETED
Conditions: Female Infertility
Interventions: DRUG: Clomid, Respatio and Ethinyl estradiol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of HRS9531 Injection in Obese Subjects Without Diabetes
Status: ACTIVE_NOT_RECRUITING
Conditions: Overweight or Obesity
Interventions: DRUG: HRS9531 injection|DRUG: HRS9531 injection|DRUG: HRS9531 injection|DRUG: HRS9531 injection|DRUG: HRS9531 injection Placebo|DRUG: HRS9531 injection Placebo|DRUG: HRS9531 injection Placebo|DRUG: HRS9531 injection Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Lidocaine Injection: A Nove Block Therapy for Stroke-related Dysphagia
Status: COMPLETED
Conditions: Dysphagia
Interventions: BEHAVIORAL: Comprehensive rehabilitation|PROCEDURE: Injection|DRUG: Lidocaine Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Non-surgical Periodontal Therapy on Gingival Crevicular Fluid Interleukin-21 Levels
Status: COMPLETED
Conditions: Chronic Peridontitis Patients|Chronic Gingivitis|Healthy
Interventions: PROCEDURE: non surgical periodontal therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Single Oral Doses of VBY-036 in Healthy Volunteers (VBY036P1A)
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: VBY-036|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multi-national, Multi-center, Randomized Controlled Trial to Evaluate the Clinical Utility of Non-invasive Endometrial Receptivity Test (Ora) in Patients With Implantation Failure
Status: RECRUITING
Conditions: IVF|Window of Implantation|microRNA|Implantation|Non-invasive Testing|Endometrial Receptivity
Interventions: DIAGNOSTIC_TEST: Window of Implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Immunogenicity and Safety of Bivalent Meningococcal Serogroups A and C Tetanus Toxoid Conjugate Vaccine in Chinese
Status: COMPLETED
Conditions: Vaccine
Interventions: BIOLOGICAL: experimental vaccine|BIOLOGICAL: Positive control vaccine 1|BIOLOGICAL: Positive control vaccine 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of Omalizumab in Children (6 - < 12 Years) With Moderate-severe, Inadequately Controlled Allergic Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Omalizumab|DRUG: Placebo|DRUG: Fluticasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of LY900014 in Participants With Type 2 Diabetes on Insulin Injection Therapy
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: LY900014|DRUG: Insulin Lispro
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Use of 2-Octyl Cyanoacrylate (Dermabond) in Neonatal Circumcision: A Randomized Controlled Trial
Status: RECRUITING
Conditions: Redundant Prepuce
Interventions: DRUG: 2-octyl cyanoacrylate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Factors Influencing Volumetric MR-HIFU Ablation of Uterine Fibroids
Status: COMPLETED
Conditions: Uterine Fibroid
Interventions: DEVICE: Contrast-enhancement ultrasound with Sonovue
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluating the Infectivity, Safety, and Immunogenicity of a Respiratory Syncytial Virus Vaccine (RSV 6120/∆NS2/1030s) in RSV-Seropositive Children and RSV-Seronegative Infants and Children
Status: COMPLETED
Conditions: RSV Infection
Interventions: BIOLOGICAL: RSV 6120/∆NS2/1030s|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Efficacy and Safety of Apremilast (CC-10004) in Japanese Subjects With Palmoplantar Pustulosis
Status: COMPLETED
Conditions: Palmoplantaris Pustulosis
Interventions: DRUG: Apremilast|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: First-in-Human Exploratory Single Ascending Dose of GLPG0974
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: GLPG0974|DRUG: GLPG0974
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Activated Recombinant Human Factor VII to Reduce Bleeding Caused by Warfarin Treatment
Status: COMPLETED
Conditions: Haemostasis|Healthy
Interventions: DRUG: warfarin|DRUG: eptacog alfa (activated)|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Drug-drug Interaction and Safety Between "BR6001-1" and "BR6001-2"
Status: COMPLETED
Conditions: Gastric or Duodenal Ulcer
Interventions: DRUG: BR6001-1|DRUG: BR6001-2
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Use of Probiotic Bacteria in Prevention of Allergic Disease in Children 1999-2008
Status: UNKNOWN
Conditions: Atopic Dermatitis|Food Hypersensitivity|Allergic Rhinitis, Seasonal|Allergic Conjunctivitis|Asthma
Interventions: DRUG: Mixture of probiotic bacteria and prebiotic oligosaccharide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Magnetic Resonance Spectroscopy at Term-equivalent Age and Executive Functions at 5 Years of Age Corrected in Very Preterm Infants
Status: UNKNOWN
Conditions: Children Born Very Prematurely in Relation to Structural Brain Abnormalities
Interventions: OTHER: an advanced technique as magnetic resonance spectroscopy (MRS)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Immunogenicity of Single Dose Choleragarde® in HIV-Seropositive Adults
Status: COMPLETED
Conditions: Cholera|Vibrio Infections|Diarrhea
Interventions: BIOLOGICAL: CholeraGarde®|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Tocilizumab for Patients With Giant Cell Arteritis
Status: COMPLETED
Conditions: Giant Cell Arteritis
Interventions: DRUG: Tocilizumab + Glucocorticoids (GCs)|DRUG: Placebo + Glucocorticoids (GCs)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vorinostat, Paclitaxel, and Carboplatin in Treating Patients With Advanced or Refractory Solid Tumors
Status: COMPLETED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: vorinostat|DRUG: paclitaxel|DRUG: carboplatin|OTHER: laboratory biomarker analysis|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Urate Lowering Therapies and Left Ventricular Diastolic Dysfunction
Status: UNKNOWN
Conditions: Hyperuricemia|Metabolic Syndrome|Left Ventricular Diastolic Dysfunction
Interventions: DRUG: Febuxostat 40 mg|DRUG: Benzbromarone 50mg|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare the Effect of a Double Dose of Two Long-acting Insulin Therapies in Participants With Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Insulin Peglispro|DRUG: Insulin Glargine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pivotal-Safety and Therapeutic Measures of tDCS in Patients With Refractory Focal Epilepsy
Status: RECRUITING
Conditions: Refractory Epilepsy|Focal Seizure|Seizures, Focal|Seizures|Epilepsy in Children|Epilepsy|Epilepsy, Tonic-Clonic
Interventions: DEVICE: STARSTIM device|DEVICE: Sham Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: 24-week Study Comparing Lixisenatide to Sitagliptin as add-on to Metformin in Obese Type 2 Diabetic Patients Younger Than 50 Years
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Lixisenatide (AVE0010)|DRUG: Lixisenatide Placebo|DEVICE: Pen auto-injector|DRUG: Sitagliptin|DRUG: Sitagliptin Placebo|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Hippocampal Network Function in Epilepsy
Status: ENROLLING_BY_INVITATION
Conditions: Mesial Temporal Lobe Epilepsy
Interventions: DEVICE: TMS targeting the hippocampus indirectly via its network
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Circulating Tumor Cell Reducing No-touch Nephrectomy
Status: COMPLETED
Conditions: Renal Cell Carcinoma|Circulating Tumor Cell
Interventions: PROCEDURE: No-touch laparoscopic radical nephrectomy|PROCEDURE: Conventional laparoscopic radical nephrectomy|PROCEDURE: Laparoscopic total nephrectomy control arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Injection Snoreplasty: Comparison Between Ethanol and Ethanolamine Oleate
Status: UNKNOWN
Conditions: Snoring|Apnea
Interventions: PROCEDURE: Injection Snoreplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Stereotactic Body Radiotherapy and Radiofrequency Ablation for Lung Tumors Near Central Airways
Status: COMPLETED
Conditions: Lung Cancer
Interventions: RADIATION: Stereotactic Body Radiation|RADIATION: Radiofrequency Ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Parenteral ω-3 Polyunsaturated Fatty Acid on Postoperative Complications of Patients With Crohn's Disease
Status: UNKNOWN
Conditions: Crohn Disease
Interventions: DRUG: ω-3 polyunsaturated fatty acid|PROCEDURE: Intestinal surgery for Crohn's Disease
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: High-Flow Heated and Humidified Oxygen Therapy and Gastric Distension
Status: COMPLETED
Conditions: Gastric Distention
Interventions: DEVICE: High-Flow Heated and Humidified Oxygen Therapy (HFHHNO)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Single Dose Study With 4SC-203 in Healthy Volunteers
Status: COMPLETED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: 4SC-203|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Single Doses of MK -5475 on Pulmonary Vascular Resistance (MK-5475-002)
Status: COMPLETED
Conditions: Pulmonary Arterial Hypertension
Interventions: DRUG: MK-5475|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Rilematovir (JNJ-53718678) in Adult Outpatients With Respiratory Syncytial Virus (RSV) Infection
Status: TERMINATED
Conditions: Respiratory Syncytial Virus
Interventions: DRUG: Rilematovir|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Spouses' Involvement Through Case Management in Older Patients' Fast-track Program
Status: COMPLETED
Conditions: Arthroplasty, Replacement, Hip
Interventions: BEHAVIORAL: Case management|BEHAVIORAL: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: CCTA Improves Clinical Management of Stable Chest Pain
Status: RECRUITING
Conditions: Coronary Computed Tomography Angiography|Stable Chest Pain|Optimal Medical Therapy|Invasive Coronary Angiography|Revascularization|Major Adverse Cardiovascular Events|Coronary Artery Disease
Interventions: DIAGNOSTIC_TEST: CCTA
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Microbiology of Severe Acute Tonsillitis, Peritonsillar Cellulitis, and Infectious Mononucleosis
Status: UNKNOWN
Conditions: Acute Tonsillitis|Peritonsillar Cellulitis|Infectious Mononucleosis
Interventions: OTHER: Throat swabbing
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Botulinum Toxin Type A Versus Saline Trigger Point Injections for Myofascial Pelvic Pain
Status: UNKNOWN
Conditions: Myofascial Pelvic Pain
Interventions: DRUG: Intervention-Botulinum Toxin Type A|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pancreatic Stent for Distal Pancreatectomy
Status: COMPLETED
Conditions: Distal Pancreatectomy
Interventions: DEVICE: Pancreatic stent: PSOF COOK®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Peptides Derived From Fermented Milk on Blood Pressure Regulation System in Healthy Volunteers.
Status: TERMINATED
Conditions: Healthy
Interventions: DRUG: repeated intake of fermented milk followed by a single oral dose of an ACE inhibitor
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Lymphedema After Urologic Surgery
Status: RECRUITING
Conditions: Urinary Bladder Neoplasms|Prostatic Neoplasms|Testicular Neoplasms|Penile Cancer
Interventions: OTHER: Self-reported lymphedema|OTHER: Dielectric constant ratio|OTHER: Limb volume
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: HRS9531 Controls Weight Regain in Obese Subjects
Status: ACTIVE_NOT_RECRUITING
Conditions: Obesity
Interventions: DRUG: HRS9531|DRUG: HRS9531 placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Exercise Prehab in Older Adults With Hematologic Malignancies
Status: UNKNOWN
Conditions: Hematopoietic and Lymphoid Cell Neoplasm
Interventions: BEHAVIORAL: Exercise Intervention|OTHER: Laboratory Biomarker Analysis|PROCEDURE: Physical Therapy|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Pilot Study of FOLFIRINOX in Combination With Neoadjuvant Radiation for Gastric and GE Junction Cancers
Status: UNKNOWN
Conditions: GastroEsophageal Cancer
Interventions: DRUG: Irinotecan|DRUG: Oxaliplatin|DRUG: Leucovorin|DRUG: 5-Fluorouracil|DRUG: Paclitaxel|RADIATION: Radiation Therapy|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Testing of Different Tourniquet Pressure Used for Postoperative Pain Reduction in Total Knee Arthroplasty
Status: UNKNOWN
Conditions: Osteoarthritis, Knee
Interventions: DEVICE: Tourniquet: Systolic blood pressure + 75 mmHg|DEVICE: Tourniquet: Systolic blood pressure + 100 mmHg|DEVICE: Tourniquet: Systolic blood pressure + 150 mmHg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial of Chazhu Xiaozhi Decoction Against Non-alcoholic Fatty Liver Disease
Status: NOT_YET_RECRUITING
Conditions: Hepatic Steatosis|Symptoms and Signs
Interventions: DRUG: Chazhu Xiaozhi decoction|DRUG: Control placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Cyclobenzaprine Hydrochloride 10 mg Tablets, USP Under Fasting Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Cyclobenzaprine hydrochloride 10 mg tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Efficacy of Calmmax Cream in the Management of Chronic Uremic Pruritus
Status: UNKNOWN
Conditions: Calmmax Cream on UP in CKD Patients.
Interventions: DRUG: Callmax cream application over affected skin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Determine Effective Prophylaxis and Treatment of Nelfinavir-Associated Diarrhea
Status: TERMINATED
Conditions: Diarrhea
Interventions: DRUG: Calcium Carbonate|DRUG: nelfinavir|DRUG: lamivudine|DRUG: loperamide|OTHER: Calcium carbonate not administered|DRUG: nelfinavir|DRUG: lamivudine + zidovudine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Limb Remote Ischemic Preconditioning for Heart and Intestinal Protection During Laparoscopic Colorectal Surgery
Status: UNKNOWN
Conditions: Laparoscopic Colorectal Surgery
Interventions: PROCEDURE: Limb remote ischemic preconditioning (LRIP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Antidepressant Therapy in Treating Bipolar Type II Major Depression
Status: COMPLETED
Conditions: Bipolar Disorder|Depression
Interventions: DRUG: Venlafaxine|DRUG: Lithium Carbonate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Improving Everyday Task Performance Through Repeated Practice in Virtual Reality.
Status: COMPLETED
Conditions: Alzheimer Disease|Mild Dementia|Mild Cognitive Impairment|Dementia|Dementia, Vascular|Dementia Alzheimers|Dementia, Mild|Dementia, Mixed|Dementia of Alzheimer Type
Interventions: BEHAVIORAL: Virtual Kitchen Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Effect of Biphasic Insulin Aspart 50 in Patients With Type 2 Diabetes Mellitus.
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: biphasic insulin aspart|DRUG: biphasic human insulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Applications Site Reactions After Injection of Insulin Detemir and Saline in Subjects With Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: DRUG: insulin detemir|DRUG: saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Immunosuppressants With Adalimumab Biosimilars vs Corticosteroids on Noninfectious Uveitis
Status: RECRUITING
Conditions: Uveitis
Interventions: DRUG: Adalimumab Biosimilars Injection|DRUG: Corticosteroid|DRUG: Immunosuppressive Agents
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transmuscular Quadratus Lumborum Block for Postoperative Pain After Laparoscopic Adrenalectomy
Status: COMPLETED
Conditions: Pain Management|Nerve Block|Laparoscopic Adrenalectomy
Interventions: PROCEDURE: single-injection QLB(quadratus lumborum block)|PROCEDURE: Placebo Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lamotrigine Alone Compared to Lamotrigine Plus Antidepressant for the Treatment of Bipolar II Depression
Status: COMPLETED
Conditions: Bipolar II Disorder, Most Recent Episode Major Depressive
Interventions: DRUG: Lamotrigine|DRUG: Lamotrigine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: OXN PR Compared to OxyPR to Demonstrate Non-inferiority in Pain & Locomotor Function & Improvement in Symptoms of Constipation in OA Subjects
Status: COMPLETED
Conditions: Chronic Osteoarthritis
Interventions: DRUG: Oxycodone naloxone prolonged release tablets (OXN)|DRUG: oxycodone prolonged release tablet|DRUG: oxycodone naloxone tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing Sentinel Lymph Node (SLN) Biopsy With Standard Neck Dissection for Patients With Early-Stage Oral Cavity Cancer
Status: RECRUITING
Conditions: Buccal Mucosa Squamous Cell Carcinoma|Floor of Mouth Squamous Cell Carcinoma|Gingival Squamous Cell Carcinoma|Hard Palate Squamous Cell Carcinoma|Lip Squamous Cell Carcinoma|Lower Alveolar Ridge Squamous Cell Carcinoma|Oral Cavity Squamous Cell Carcinoma|Retromolar Trigone Squamous Cell Carcinoma|Stage I Lip and Oral Cavity Cancer AJCC v8|Stage II Lip and Oral Cavity Cancer AJCC v8|Tongue Squamous Cell Carcinoma|Upper Alveolar Ridge Squamous Cell Carcinoma
Interventions: PROCEDURE: Computed Tomography (CT)|DRUG: Imaging Agent|PROCEDURE: Neck Dissection|PROCEDURE: Planar Imaging|PROCEDURE: Sentinel Lymph Node Biopsy|PROCEDURE: Single Photon Emission Computed Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hepatectomy Combined With Camrelizumab and Apatinib in CNLC Stage IIIb HCC
Status: RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Hepatectomy Combined With Camrelizumab and Apatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Enhancing Exposure Therapy for Post Traumatic Stress Disorder (PTSD): Virtual Reality and Imaginal Exposure With a Cognitive Enhancer
Status: COMPLETED
Conditions: Post Traumatic Stress Disorder
Interventions: DRUG: DCS (D-Cycloserine ) + Prolonged Imaginal Exposure|DRUG: DCS (D-Cycloserine ) + Virtual Reality Exposure|DRUG: Placebo + Prolonged Imaginal Exposure|DRUG: Placebo (sugar pill) + Virtual Reality Exposure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial on Contrast-enhanced Ultrasound Versus Conventional Ultrasound Guided Biopsy of Liver Neoplasms
Status: UNKNOWN
Conditions: Liver Neoplasms
Interventions: OTHER: CEUS guided biopsy|OTHER: US guided biopsy|DEVICE: Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Restoration® Anatomic Dual Mobility (ADM) X3® Acetabular System Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Arthroplasty, Replacement, Hip
Interventions: DEVICE: Restoration ADM X3 Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Medical & Economical Evaluation of Fenestrated & Branched Stent-grafts to Treat Complex Aortic Aneurysms
Status: COMPLETED
Conditions: Aortic Aneurysms
Interventions: DEVICE: Endovascular aortic repair with branched/fenestrated stent-graft|PROCEDURE: Open Surgical Repair
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of an Anti-HER3 Antibody, HMBD-001, With or Without Chemotherapy in Patients With Solid Tumors Harboring an NRG1 Fusion or HER3 Mutation
Status: RECRUITING
Conditions: Non-Small Cell Lung Cancer|Pancreatic Cancer|Locally Advanced Solid Tumor|Metastatic Solid Tumor
Interventions: DRUG: HMBD-001|DRUG: Docetaxel|DRUG: Nab-paclitaxel|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Caduet vs Usual Care in Subjects With Hypertension and Additional Risk Factors
Status: COMPLETED
Conditions: Hypertension|Hypercholesterolemia
Interventions: DRUG: Amlodipine besylate/atorvastatin calcium single pill combination
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: pCO2 Oscillations During Exercise: Relation to Cerebral Blood Flow and to Cognitive Dysfunction in COPD
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: OTHER: Pulmonary Rehabilitation program
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Preventing Childhood Antibiotic-associated Diarrhea by Prebiotics
Status: COMPLETED
Conditions: Antibiotic-Associated Diarrhea
Interventions: DIETARY_SUPPLEMENT: Inulin and fructo-oligosaccharides.|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Linagliptin 2.5 mg Twice Daily Versus 5 mg Once Daily as add-on Therapy to Twice Daily Metformin in Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: linagliptin low dose|DRUG: placebo|DRUG: linagliptin medium dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Prospective Cohort Study for Patients With Adrenal Diseases
Status: ENROLLING_BY_INVITATION
Conditions: Adrenal Adenoma|Cushing Syndrome|Pheochromocytoma|Adrenal Incidentaloma|Adrenocortical Carcinoma|Primary Hyperaldosteronism
Interventions: OTHER: Hormone study and Imaging study
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: S0204 Thalidomide, Chemotherapy, and Peripheral Stem Cell Transplant in Treating Patients With Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: BIOLOGICAL: filgrastim|BIOLOGICAL: sargramostim|DRUG: cyclophosphamide|DRUG: dexamethasone|DRUG: melphalan|DRUG: prednisone|DRUG: thalidomide|PROCEDURE: peripheral blood stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: AuraGain and iGel Crossover Comparison
Status: TERMINATED
Conditions: Airway Management|Laryngeal Mask Airway
Interventions: DEVICE: Insertion of Ambu AuraGain laryngeal mask airway and Igel|DEVICE: Fibreoptic assessment with Ambu A-scope|DEVICE: Ability to insert nasogastric tube|DEVICE: Measurement of OLP|DEVICE: Ability to perform positive pressure ventilation|DEVICE: Assessment of ease of insertion|DEVICE: Record number of manipulations|DEVICE: Assessment of device related trauma
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: S0008: Chemotherapy Plus Biological Therapy in Treating Patients With Melanoma
Status: COMPLETED
Conditions: Melanoma (Skin)
Interventions: BIOLOGICAL: interleukin-2|BIOLOGICAL: filgrastim|BIOLOGICAL: interferon alfa|DRUG: cisplatin|DRUG: dacarbazine|DRUG: vinblastine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immune Profiles and Circulating Tumor Cell Status Following Prostate Cryotherapy
Status: UNKNOWN
Conditions: Prostate Cancer|Immune Profile|Circulating Cancer Cells|Clinical Corelation
Interventions: PROCEDURE: Prostate cryotherapy|PROCEDURE: Radical prostatectomy|PROCEDURE: Radiation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study in Participants With Non-cirrhotic NASH With Fibrosis
Status: COMPLETED
Conditions: Non-Cirrhotic Non-alcoholic Steatohepatitis With Fibrosis
Interventions: DRUG: AZD4831|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Nelfinavir as Bortezomib-sensitizing Drug in Patients With Proteasome Inhibitor-nonresponsive Myeloma
Status: COMPLETED
Conditions: Myeloma
Interventions: DRUG: Nelfinavir|DRUG: bortezomib|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of Genakumab for Injection in Chinese Healthy Volunteers
Status: UNKNOWN
Conditions: Juvenile Idiopathic Arthritis
Interventions: DRUG: Genakumab|DRUG: Placebo for this trial
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: The Comparison of the Analgesic Effects of Dezocine and Sufentanil in Patient-controlled Analgesia After Laryngectomy
Status: COMPLETED
Conditions: Patient-controlled Analgesia
Interventions: DRUG: Dezocine|DRUG: Sufentanil injection|DRUG: Flurbiprofen|DRUG: Granisetron Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Proof of Concept Human Study: Dietary Intervention to Modify Intestinal Inflammation in IBD
Status: RECRUITING
Conditions: Reduction of Intestinal Inflammatory Activity
Interventions: DIETARY_SUPPLEMENT: Gluten-free diet
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT