pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Phase II Study With ITF2984 in Acromegalic Patients
Status: COMPLETED
Conditions: Acromegaly
Interventions: DRUG: Octreotide|DRUG: ITF2984 500 mcg|DRUG: ITF2984 1000 mcg|DRUG: ITF2984 2000 mcg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cathodal Transcranial Direct Current Stimulation in Patients With Drug-resistant Focal Epilepsy
Status: RECRUITING
Conditions: Drug Resistant Epilepsy
Interventions: DEVICE: Transcranial Direct Current Stimulation-TessaNova (Teknofil-Turkiye)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Electronic Cigarettes and Tobacco Cigarettes on Cardiovascular Function and Oxidative Stress
Status: COMPLETED
Conditions: Cardiovascular Risk Factor
Interventions: DEVICE: e-cigarette (PG+VG without nicotine; low temperature)|DEVICE: e-cigarette (PG+VG with nicotine; low temperature)|DEVICE: e-cigarette (PG+VG without nicotine; high temperature)|DEVICE: e-cigarette (PG+VG with nicotine; high temperature)|OTHER: tobacco cigarette
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Aromatherapy on Preoperative Anxiety Level
Status: COMPLETED
Conditions: Anxiety|Aromatherapy|Anesthesia, Spinal|Postoperative Period
Interventions: DRUG: lavender essential oil inhaled using cotton balls|DRUG: lavender essential oil inhaled using face mask|DRUG: Distilled water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Relationship Between Pet Therapy and "Well-being" in Geriatric Rehabilitation In-patients
Status: UNKNOWN
Conditions: Cerebrovascular Accident|Hip Fracture
Interventions: BEHAVIORAL: care of guinea pigs|BEHAVIORAL: guinea pigs
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Dietary Interventions on the Brain in Mild Cognitive Impairment (MCI)
Status: COMPLETED
Conditions: Mild Cognitive Impairment
Interventions: BEHAVIORAL: caloric restriction|BEHAVIORAL: omega-3 supplementation|BEHAVIORAL: resveratrol supplementation|BEHAVIORAL: Placebo|BEHAVIORAL: 2nd step: intervention + physical / cognitive training|BEHAVIORAL: 2nd step: intervention + control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Go Fit Fast, Recovery Trajectory Using PROMIS®, Linking PROMIS®
Status: RECRUITING
Conditions: Hip Fractures|Tibial Fractures|Ankle Fractures|Humeral Fracture, Proximal|Distal Radius Fracture
Interventions: OTHER: All treatments will remain the standard (routine) care procedures based on individual clinician's judgment and the patient characteristics.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Flaxseed Mucilage and Satiety
Status: UNKNOWN
Conditions: Appetite
Interventions: DIETARY_SUPPLEMENT: Flaxseed drink|DIETARY_SUPPLEMENT: Flaxseed drink|DIETARY_SUPPLEMENT: Flaxseed tablet|DIETARY_SUPPLEMENT: Control drink
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Sequential Therapy Versus Quadruple Therapy as Second Line Treatment After Failure of the Standard Triple Therapy for H Pylori Infection
Status: COMPLETED
Conditions: Optimization of Second Line Treatment Protocol for H Pylori Eradication
Interventions: DRUG: Lansoprazole , Tab Amoxycillin , Tab Clarithromycin ,Tab Tinidazole|DRUG: Lansoprazole, Bismuth Subsalicylate, Metronidazole, Tetracycline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SU011248 in Combination With Irinotecan and Cetuximab as a Second Line Regimen for Stage IV Colorectal Cancer
Status: TERMINATED
Conditions: Colorectal Carcinoma
Interventions: DRUG: SU011248|DRUG: Irinotecan|DRUG: Cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Microbiota Restoration Therapy for Recurrent Clostridium Difficile Infection (PUNCHCD3)
Status: COMPLETED
Conditions: Clostridium Difficile Infection (CDI)
Interventions: DRUG: RBX2660|DRUG: Placebo|DRUG: Open label RBX2660 (only for confirmed CDI recurrence)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Black Bean (Phaseolus Vulgaris L.) Protein Hydrolysates Reduce Acute Postprandial Glucose Levels
Status: COMPLETED
Conditions: PreDiabetes
Interventions: DIETARY_SUPPLEMENT: Black bean protein hydrolysates (BPH)|OTHER: Commercial non-caloric beverage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Relative Bioavailability of Gantenerumab Produced by G4 Process Versus G3 Process Following Subcutaneous (SC) Injection in Healthy Participants
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DRUG: Gantenerumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Study of Hemp Oil CBD for Evaluation of Efficacy and Safety in Treatment of Pain, Anxiety and Insomnia Management
Status: UNKNOWN
Conditions: CBD|Pain, Chronic|Anxiety|Insomnia|Opioid Use
Interventions: DRUG: CBD
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hypothermic Oxygenated (HOPE) Versus Normothermic Machine Perfusion (NMP) in Human Liver Transplantation
Status: RECRUITING
Conditions: Hepatocellular Injury|Liver Transplant Disorder
Interventions: DEVICE: Hypothermic oxygenated perfusion (HOPE)|DEVICE: Normothermic machine perfusion (NMP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant SBRT With Concomitant Capecitabine in Resectable Pancreatic Cancer
Status: COMPLETED
Conditions: Stage IA Pancreatic Cancer|Stage IB Pancreatic Cancer|Stage IIA Pancreatic Cancer|Stage IIB Pancreatic Cancer
Interventions: RADIATION: stereotactic body radiation therapy|DRUG: capecitabine|PROCEDURE: therapeutic conventional surgery|PROCEDURE: magnetic resonance imaging|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Functional Outcomes of Ejaculation-preserving Partial Trans Urethral Resection of the Prostate With Complete Trans Urethral Resection of the Prostate for Benign Prostatic Obstruction
Status: RECRUITING
Conditions: Benign Prostatic Hyperplasia
Interventions: PROCEDURE: Partial surgery preserving the prostatic apex|PROCEDURE: Conventional endoscopic prostatic surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Dehydroepiandrosterone Supplementation for Poor Responder Patients During in Vitro Fertilization Treatment
Status: COMPLETED
Conditions: Ovarian Stimulation
Interventions: DRUG: dehydroepiandrosterone crystalline fine powder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of SNS-101 (Anti VISTA) Monotherapy and in Combination With Cemiplimab in Patients With Advanced Solid Tumors
Status: RECRUITING
Conditions: Solid Tumor, Adult|Advanced Solid Tumor|Head and Neck Cancer|Breast Cancer|Colon Cancer|Pancreatic Cancer|Gastric Cancer|Esophageal Cancer|Prostate Cancer|Uterine Cancer|Cervix Cancer|Ovarian Cancer|Kidney Cancer|Bladder Cancer|Thyroid Cancer|Melanoma|Sarcoma|Advanced Cancer|Metastatic Cancer|Refractory Cancer|Non Small Cell Lung Cancer
Interventions: DRUG: SNS-101 (anti-VISTA)|DRUG: Cemiplimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rosiglitazone Effect on Mitochondria and Lipoatrophy
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Rosiglitazone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Linperlisib in Combination With CHOP in Previously Untreated Peripheral T-Cell Lymphoma
Status: RECRUITING
Conditions: Peripheral T-cell Lymphoma
Interventions: DRUG: Linperlisib in combination with CHOP
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Robot Mediated Therapy-Upper Limb Outcomes in Stroke
Status: NOT_YET_RECRUITING
Conditions: Stroke, Acute
Interventions: DEVICE: Robot mediated upper limb therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Application of Botulinum Toxin at the Yonsei Point for the Treatment of Gummy Smile
Status: COMPLETED
Conditions: Smiling|Botulinum Toxins, Type A
Interventions: PROCEDURE: the injection of onabotulinumtoxinA at different point
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Folic Acid on the Presentation of Nuclear Abnormalities in People With a History Drug Abuse
Status: NOT_YET_RECRUITING
Conditions: Drug Abuse|Genotoxicity
Interventions: DRUG: Folic Acid 5 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Allogeneic Human Umbilical Cord Mesenchymal Stem Cells for a Single Male Patient With Duchenne Muscular Dystrophy (DMD)
Status: COMPLETED
Conditions: Duchenne's Muscular Dystrophy
Interventions: BIOLOGICAL: Umbilical Cord Mesenchymal Stem Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Electrocorticography in Mapping Functional Brain Areas During Surgery in Patients With Brain Tumors
Status: RECRUITING
Conditions: Brain Neoplasm|Metastatic Malignant Neoplasm in the Brain|Recurrent Brain Neoplasm
Interventions: PROCEDURE: Direct Electrocortical Stimulation|OTHER: Electrocorticography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Hydroxychloroquine With or Without Erlotinib in Advanced Non-small Cell Lung Cancer (NSCLC)
Status: TERMINATED
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: erlotinib|DRUG: hydroxychloroquine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Temsirolimus, Irinotecan Hydrochloride, and Temozolomide in Treating Younger Patients With Relapsed or Refractory Solid Tumors
Status: COMPLETED
Conditions: Unspecified Childhood Solid Tumor, Protocol Specific
Interventions: DRUG: temsirolimus|DRUG: temozolomide|DRUG: irinotecan hydrochloride|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study on Safety and Performance of Medtentia Mitral Valve Repair System in Surgical Repair of Mitral Regurgitation
Status: TERMINATED
Conditions: Mitral Regurgitation|Mitral Insufficiency
Interventions: DEVICE: Mitral valve repair using the Medtentia Annuloplasty Ring (MAR)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Electroacupuncture Intervention in Catheter Ablation of Atrial Fibrillation
Status: NOT_YET_RECRUITING
Conditions: Atrial Fibrillation|Catheter Ablation
Interventions: PROCEDURE: Acupuncture plus morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Research Study to See How Much Semaglutide and SNAC is in the Milk of Healthy, Breastfeeding Women Taking Semaglutide Tablets
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Oral semaglutide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Fostair® on Biomarkers of Platelet Adhesion in Idiopathic Pulmonary Fibrosis
Status: COMPLETED
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: DRUG: fostair|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Pharmacokinetics of BIRB 796 BS Tablets Administered Twice Daily Orally to Healthy Human Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BIBR 796 BS|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: NeoAdj. Therapy Comparing Sacituzumab Govitecan (SG) vs. SG+Pembrolizumab in Low-risk, Triple-neg. EBC (ADAPT-TN-III)
Status: NOT_YET_RECRUITING
Conditions: Triple Negative Breast Cancer
Interventions: DRUG: Sacituzumab govitecan|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ambisome® Preemptive Treatment of Multiple Candida Colonization in Sepsis Patients
Status: UNKNOWN
Conditions: Sepsis|Candida
Interventions: DRUG: Amphotericine in liposome (Ambisome®)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Eyecontrol coMmunication Platform for dEliRium manaGemEnt in Intensive Care Units (EMERGE)
Status: RECRUITING
Conditions: Delirium|Delirium in Old Age|Critical Illness|Intensive Care Unit Delirium
Interventions: DEVICE: EyeControl-Pro|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Frontal iTBS for Impulsivity and Suicidal Ideation in Veterans With Mild Traumatic Brain Injury
Status: RECRUITING
Conditions: Mild Traumatic Brain Injury|Suicidal Ideation|Impulsivity
Interventions: DEVICE: intermittent theta burst stimulation|DEVICE: placebo intermittent theta burst stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Dasatinib (BMS-354825) in Patients With Solid Tumors
Status: COMPLETED
Conditions: Tumors
Interventions: DRUG: Dasatinib|DRUG: Dasatinib|DRUG: Dasatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy in Treating Children With Newly Diagnosed Acute Lymphoblastic Leukemia
Status: COMPLETED
Conditions: Leukemia
Interventions: DRUG: asparaginase|DRUG: cyclophosphamide|DRUG: cytarabine|DRUG: daunorubicin hydrochloride|DRUG: dexamethasone|DRUG: doxorubicin hydrochloride|DRUG: mercaptopurine|DRUG: methotrexate|DRUG: pegaspargase|DRUG: prednisone|DRUG: therapeutic hydrocortisone|DRUG: thioguanine|DRUG: vincristine sulfate|RADIATION: low-LET cobalt-60 gamma ray therapy|RADIATION: low-LET photon therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Topical Imiquimod 5% Cream for Treatment of Cutaneous Neurofibromas in Adults With Neurofibromatosis 1
Status: COMPLETED
Conditions: Neurofibromatosis Type 1|Cutaneous Neurofibromas
Interventions: DRUG: Imiquimod 5% Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Sotagliflozin Prototype Tablets With Reference Tablet in Healthy Subjects
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus|Type 2 Diabetes Mellitus
Interventions: DRUG: sotagliflozin (SAR439954)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Drug-Drug Interaction Study of IV QPX2014 Combined With QPX7728 in Healthy Adult Subjects
Status: COMPLETED
Conditions: Bacterial Infections
Interventions: DRUG: QPX7728|DRUG: QPX2014
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: MEtformin and Lorcaserin for WeighT Loss in Schizophrenia
Status: TERMINATED
Conditions: Schizophrenia|Schizoaffective Disorder|Overweight
Interventions: DRUG: Lorcaserin|DRUG: Metformin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sequential Intravesical Bacillus Calmette-Guérin and Electromotive Mitomycin-C After Transuretheral Resection
Status: TERMINATED
Conditions: Bladder Carcinoma
Interventions: DEVICE: Intravesical BCG and EMDA/MMC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I, Open-label Study to Assess Bioavailability of a Single Oral Dose of AZD9291 vs an IV Dose of [14C]AZD9291
Status: COMPLETED
Conditions: Oncology
Interventions: DRUG: AZD9291|DRUG: [14C]AZD9291
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TOlerance MOlecular and Genome-wide Studies With Renal Allograft Recipient Material
Status: COMPLETED
Conditions: Kidney Transplantation
Interventions: GENETIC: High throughput DNA and RNA sequencing
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Digital Health Coaching Program on Self-efficacy and Patient Reported Outcomes of Patients With Newly Diagnosed Acute Myeloid Leukemia or Chronic Lymphocytic Leukemia
Status: COMPLETED
Conditions: Acute Myeloid Leukemia|Chronic Lymphocytic Leukemia
Interventions: OTHER: Educational Intervention|OTHER: Questionnaire Administration|OTHER: Supportive Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of Physical Therapy Modalities and Kinesio Taping in Patients With Knee Osteoarthritis
Status: UNKNOWN
Conditions: Knee Osteoarthritis|Knee Pain Chronic
Interventions: OTHER: physical therapy modalities and exercise|OTHER: kinesio taping and exercise|OTHER: exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Accelerating COVID-19 Clinical Recovery in the Outpatient Setting: Retrospective Analysis
Status: UNKNOWN
Conditions: COVID-19|COVID-19 Pandemic|COVID-19 Respiratory Infection|SARS CoV 2 Infection|SARS-CoV-2 Acute Respiratory Disease
Interventions: DRUG: ClorNovir® (Chlorpheniramine) 0.4% Nasal Spray
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Trial for Salvage Re-Irradiation of Metastatic Spine Lesions Using Single-Fraction Stereotactic Radiosurgery
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Spine Lesions
Interventions: RADIATION: single-fraction radiation|DEVICE: MRI and/or CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Between 2l vs 3l in HFNC During the Initial Management of Severe Bronchiolitis in Infants
Status: COMPLETED
Conditions: Bronchiolitis
Interventions: DEVICE: treatment by 2l/min/kg in High Flow Nasal cannula (HFNC)|DEVICE: treatment by 3l/min/kg in High Flow Nasal cannula (HFNC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Anlotinib in Patients With Gastroenteropancreatic Neuroendocrine Tumor G3
Status: UNKNOWN
Conditions: Gastroenteropancreatic Neuroendocrine Tumor G3
Interventions: DRUG: Anlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GM-CSF for Reversal of immunopAralysis in pediatriC sEpsis-induced MODS Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Pediatric Sepsis-induced MODS
Interventions: DRUG: GM-CSF
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of Ropinirole IR (Immediate Release) Tablets in Patients Who Are Diagnosed With Symptomatic Restless Legs Syndrome (RLS) Associated With Chronic Kidney Disease (CKD) Managed With Haemodialysis (Including Haemofiltration and Haemodiafiltration)
Status: TERMINATED
Conditions: Restless Legs Syndrome
Interventions: DRUG: Ropinirole immediate release (IR)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety and Immunogenicity of MEDI-517P in Healthy Adult Female Volunteers Who Are HPV-16 or HPV-18 DNA Positive
Status: COMPLETED
Conditions: Healthy
Interventions: BIOLOGICAL: MEDI 517|OTHER: Aluminum hydroxide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of the Preventing AIDS Through Live Movement and Sound (PALMS) Intervention for Minority Adolescents
Status: COMPLETED
Conditions: HIV Infections
Interventions: BEHAVIORAL: Preventing AIDS Through Live Movement and Sound (PALMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparative Study of Osteosynthesis for Chevron Osteotomy of Hallux Valgus Using Degradable Versus Non-degradable Metallic Device
Status: COMPLETED
Conditions: Hallux Valgus
Interventions: DEVICE: Fracture compressing screw ZfW 102 Königsee Implantate GmbH|DEVICE: Fracture compressing screw titanium Königsee Implantate GmbH
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study To Find Out How Fesoterodine Works In Children Aged 6 To 17 Years With Bladder Overactivity Caused By A Neurological Condition
Status: COMPLETED
Conditions: Urinary Bladder, Neurogenic
Interventions: DRUG: Fesoterodine PR 4 mg|DRUG: Fesoterodine PR 8 mg|DRUG: Fesoterodine PR 8 mg|DRUG: Oxybutynin|DRUG: Fesoterodine PR|DRUG: Fesoterodine BIC 2 mg|DRUG: Fesoterodine BIC 4 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Direct Comparison of Altered States of Consciousness Induced by LSD and Psilocybin
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: LSD|DRUG: LSD|DRUG: Psilocybin|DRUG: Psilocybin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Biomarkers in Patients With Metastatic or Recurrent Head and Neck Cancer Treated With Cisplatin and Cetuximab on ECOG-E5397
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: BIOLOGICAL: cetuximab|DRUG: cisplatin|GENETIC: gene expression analysis|GENETIC: microarray analysis|OTHER: immunohistochemistry staining method|OTHER: laboratory biomarker analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of PB-718 Injection in Chinese Obese Subjects.
Status: COMPLETED
Conditions: Obesity
Interventions: DRUG: PB-718|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Impact on Recurrence Risk of Adjuvant Transarterial Chemoinfusion (TAI) Versus Adjuvant Transarterial Chemoembolization (TACE) for Patients With Hepatocellular Carcinoma And Portal Vein Tumor Thrombosis (PVTT) After Hepatectomy : A Random, Controlled, Stage III Clinical Trial.
Status: RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: PROCEDURE: TAI|PROCEDURE: TACE|DRUG: epidoxorubicin and cisplatin and lipiodol|DRUG: mFOLFOX6 (oxaliplatin, calcium folinate, and 5-FU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate P2X7 Receptor Occupancy by JNJ-54175446 With the Newly Developed P2X7 Receptor Positron Emission Tomography (PET) Tracer 18F-JNJ-64413739
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: JNJ-54175446|DRUG: 18F-JNJ-64413739
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Ultrasound-guided Continuous Erector Spinae Plane Block Versus Thoracic Epidural Analgesia in Open Nephrectomy
Status: UNKNOWN
Conditions: Erector Spinae Plane Block|Thoracic Epidural Analgesia|Nephrectomy
Interventions: PROCEDURE: Thoracic epidural analgesia|PROCEDURE: Ultrasound guided continuous erector spinae plane block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Single Group Study to Evaluate the Efficacy of Bye Bye Bloat Capsules in Relieving Bloating and Promoting Healthy Digestion.
Status: COMPLETED
Conditions: Digestive Health|Digestion
Interventions: DIETARY_SUPPLEMENT: Bye Bye Bloat Capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improving Radical Treatment Through MRI Evaluation of Pelvic Sigmoid Cancers
Status: RECRUITING
Conditions: Cancer|Colorectal Neoplasms|Colon, Sigmoid|Magnetic Resonance Imaging|General Surgery
Interventions: OTHER: Preoperative MRI scan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Three Way Crossover Closed Loop Study With Xeris Glucagon
Status: COMPLETED
Conditions: Type1diabetes
Interventions: DEVICE: Artificial Pancreas Controller in Dual Hormone Mode|DEVICE: Artificial Pancreas Controller in Single Hormone Mode|DEVICE: Artificial Pancreas Controller in Predictive Low Glucose Suspend Mode|DRUG: XeriSol glucagon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Curved Soft-Picks on Plaque Accumulation on Patients With Gingivitis
Status: COMPLETED
Conditions: Gingivitis
Interventions: DEVICE: Soft-Picks Advanced|DEVICE: Floss
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Antimicrobial Coating Suture Coated Vicryl Plus Compared With Vicryl in Reduced Surgical Site Infection of Dental Implant Surgeries: A Uni-Blind Randomized Clinical Trial Study
Status: COMPLETED
Conditions: Infection, Surgical Site
Interventions: DRUG: Vicryl plus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Maxi-Analgesic Phase 2 Study to Compare the Analgesic Effects in Different Dosing Groups to Treat Teeth Extraction Pain
Status: WITHDRAWN
Conditions: Dental Pain
Interventions: DRUG: Full Dose Strength|DRUG: Quarter dose strength|DRUG: Half dose strength|DRUG: Acetaminophen standard dose|DRUG: Ibuprofen low dose|DRUG: Ibuprofen high dose|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Diagnostic Yield of 20-gauge Procore Needle for EUS-guided FNA Biopsy in Solid Pancreatic Lesions
Status: COMPLETED
Conditions: Pancreatic Neoplasms
Interventions: DEVICE: EUS-FNB with 20 gauge ProCore needle|DEVICE: EUS-FNB with 22 gauge ProCore needle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluating Refractive and Visual Outcomes With the Alcon Toric ReSTOR +2.5 and +3.0 Models
Status: COMPLETED
Conditions: Cataract
Interventions: DEVICE: ReSTOR Toric
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: "Fermented Dairy Beverage on Inflammation/Immune Function in Stressful Exercise"
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: OTHER: Placebo comparator|OTHER: Single Active dose|OTHER: Double Active dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Trial to Evaluate the Efficacy of a Zinc, Selenium, and L-Tyrosine Supplement in the Prevention of Thyrotoxicosis in Subjects With r25191G/A SEPP1 Polymorphism
Status: NOT_YET_RECRUITING
Conditions: Thyrotoxicosis
Interventions: DIETARY_SUPPLEMENT: zinc, selenium, and L-tyrosine in SEPP1|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Amplification With Hearing Aids for Tinnitus Relief
Status: COMPLETED
Conditions: Tinnitus, Subjective|Hearing Impairment
Interventions: DEVICE: Amplification with hearing aid|DEVICE: Customized music
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: TMS and Exercise for Post-stroke Pain
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Post-stroke Headache
Interventions: DEVICE: Active rTMS and exercise|COMBINATION_PRODUCT: Sham rTMS+Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multifunctional Nutrition Tube in Dysphagia for Nasopharyngeal Carcinoma
Status: RECRUITING
Conditions: Dysphagia
Interventions: DEVICE: Intermittent Oral-esophageal Tube Feeding|DEVICE: Nasogastric Tube Feeding|BEHAVIORAL: comprehensive rehabilitation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Safety and Efficacy of VX-661 in Combination With Ivacaftor in Subjects With Cystic Fibrosis, Homozygous for the F508del-CFTR Mutation With an Open-Label Expansion
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: VX-661|DRUG: Ivacaftor|DRUG: Placebo matched to VX-661|DRUG: Placebo matched to Ivacaftor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Preliminary Efficacy of MK0759 in Postherpetic Neuralgia (PHN)(0759-004)
Status: TERMINATED
Conditions: Neuralgia, Postherpetic
Interventions: DRUG: MK0759
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pathways for Patient-centered Diagnosis and Management of Endometriosis-associated Deep Dyspareunia
Status: COMPLETED
Conditions: Endometriosis-related Pain|Dyspareunia Deep
Interventions: DEVICE: Phallus Length Reducer|OTHER: Self-assessment of dyspareunia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Brain-Computer Interface (BCI) Based Intervention for Attention Deficit Hyperactivity Disorder (ADHD)
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: DEVICE: BCI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Anatomopathology of the Subscapularis and Infraspinatus Muscles in Children With Brachial Plexus Obstetric Paralysis
Status: TERMINATED
Conditions: Brachial Obstetrical Palsy
Interventions: PROCEDURE: arthrolysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Haloperidol for the Treatment of Nausea and Vomiting in the ED
Status: COMPLETED
Conditions: Vomiting|Nausea|Abdominal Pain|Cannabis Use
Interventions: DRUG: Haloperidol|DRUG: Ondansetron
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Mepolizumab in Chronic Obstructive Pulmonary Diseases (COPD) With Eosinophilic Bronchitis
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Diseases|Chronic Airways Limitation|Bronchitis
Interventions: DRUG: Mepolizumab|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Non Invasive Imaging Methods for Detecting PA：a Clinical PET Study of 18F-Pentixather
Status: RECRUITING
Conditions: Primary Aldosteronism Due to Adrenal Hyperplasia (Bilateral)
Interventions: OTHER: [18F]AlF-NOTA-Pentixather
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Second-look Surgery With or Without Intraperitoneal Chemotherapy in Treating Patients With Recurrent Colorectal Cancer
Status: TERMINATED
Conditions: Colorectal Cancer|Metastatic Cancer|Primary Peritoneal Cavity Cancer
Interventions: DRUG: chemotherapy|DRUG: fluorouracil|DRUG: leucovorin calcium|DRUG: mitomycin C|PROCEDURE: conventional surgery|PROCEDURE: laparoscopic surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Study of Aprepitant (MK-0869) for Chemotherapy-Induced Nausea and Vomiting (CINV) in Adolescent Participants (MK-0869-097)
Status: COMPLETED
Conditions: Vomiting
Interventions: DRUG: aprepitant|DRUG: ondansetron|DRUG: dexamethasone|DRUG: placebo to aprepitant|DRUG: placebo to dexamethasone|DRUG: rescue medication
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: SB-715992 in Treating Patients With Metastatic or Unresectable Solid Tumors or Hodgkin's or Non-Hodgkin's Lymphoma
Status: TERMINATED
Conditions: Adult Grade III Lymphomatoid Granulomatosis|Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue|Nodal Marginal Zone B-cell Lymphoma|Recurrent Adult Burkitt Lymphoma|Recurrent Adult Diffuse Large Cell Lymphoma|Recurrent Adult Diffuse Mixed Cell Lymphoma|Recurrent Adult Diffuse Small Cleaved Cell Lymphoma|Recurrent Adult Grade III Lymphomatoid Granulomatosis|Recurrent Adult Hodgkin Lymphoma|Recurrent Adult Immunoblastic Large Cell Lymphoma|Recurrent Adult Lymphoblastic Lymphoma|Recurrent Grade 1 Follicular Lymphoma|Recurrent Grade 2 Follicular Lymphoma|Recurrent Grade 3 Follicular Lymphoma|Recurrent Mantle Cell Lymphoma|Recurrent Marginal Zone Lymphoma|Recurrent Small Lymphocytic Lymphoma|Splenic Marginal Zone Lymphoma|Stage IV Adult Burkitt Lymphoma|Stage IV Adult Diffuse Large Cell Lymphoma|Stage IV Adult Diffuse Mixed Cell Lymphoma|Stage IV Adult Diffuse Small Cleaved Cell Lymphoma|Stage IV Adult Hodgkin Lymphoma|Stage IV Adult Immunoblastic Large Cell Lymphoma|Stage IV Adult Lymphoblastic Lymphoma|Stage IV Grade 1 Follicular Lymphoma|Stage IV Grade 2 Follicular Lymphoma|Stage IV Grade 3 Follicular Lymphoma|Stage IV Mantle Cell Lymphoma|Stage IV Marginal Zone Lymphoma|Stage IV Small Lymphocytic Lymphoma|Unspecified Adult Solid Tumor, Protocol Specific|Waldenström Macroglobulinemia
Interventions: DRUG: ispinesib|OTHER: laboratory biomarker analysis|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Detection of Barrett s Esophagus in Patients Without GERD Symptoms
Status: RECRUITING
Conditions: Barrett's Esophagus
Interventions: DIAGNOSTIC_TEST: EsoCheck/EsoGuard (EC/EG)|DIAGNOSTIC_TEST: Esophago-gastro-duodenoscopy (EGD)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: ReachPR Trial Resynchronization Therapy in Heart Failure Patients With Prolonged PR Interval
Status: UNKNOWN
Conditions: Atrioventricular Dyssynchrony|Heart Failure
Interventions: DEVICE: Cardiac resynchronization therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Atrial Pacing for Termination and Prevention of Atrial Fibrillation
Status: COMPLETED
Conditions: Bradycardia|Atrial Fibrillation
Interventions: DEVICE: AT501 pacemaker
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Buscopan® in Comparison With 654-II (Anisodamine) in Acute Gastric or Intestinal Pain
Status: COMPLETED
Conditions: Intestinal Diseases
Interventions: DRUG: 654-II (anisodamine)|DRUG: Buscopan® (hyoscine butylbromide)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Dyspnea in Do-not-intubate Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Respiratory Failure|Acute on Chronic Respiratory Failure|Dyspnea
Interventions: DEVICE: NIV|DEVICE: CPAP|DEVICE: Standard oxygen|DEVICE: HFNC
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Pharmacokinetic Study of Carbamylated Erythropoietin (CEPO) to Treat Patients With Acute Ischemic Stroke
Status: COMPLETED
Conditions: Acute Ischemic Stroke
Interventions: DRUG: Lu AA24493 (CEPO)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Osteopathic Manipulative Medicine in Pregnancy: Physiologic and Clinical Effects
Status: COMPLETED
Conditions: Low Back Pain|Pregnancy
Interventions: OTHER: Osteopathic Manipulative Treatment|OTHER: Placebo Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Radiofrequency Ablation Assisted Hepatectomy Versus Hepatectomy Alone for Advanced Hepatocellular Carcinoma
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma
Interventions: PROCEDURE: RFA assisted Hepatectomy|PROCEDURE: Hepatectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Salbutamol on Walking Capacity in Ambulatory ALS Patients
Status: NOT_YET_RECRUITING
Conditions: Walking Capacity|Amyotrophic Lateral Sclerosis
Interventions: DRUG: Salbutamol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: NUTRItion-driven Detoxification of OPioid Addicted patiEnts
Status: ENROLLING_BY_INVITATION
Conditions: Psychiatry
Interventions: DIETARY_SUPPLEMENT: Pomegranate juice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Solifenacin Succinate 5mg or 10mg Once Daily in the Treatment of Urgency Symptoms
Status: COMPLETED
Conditions: Urinary Bladder, Overactive
Interventions: DRUG: Solifenacin succinate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Arsenic Trioxide and Thalidomide in the Treatment of Refractory Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Arsenic Trioxide|DRUG: Thalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Apalutamide in Participants With High-Risk, Localized or Locally Advanced Prostate Cancer Who Are Candidates for Radical Prostatectomy
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostatic Neoplasms
Interventions: DRUG: Apalutamide|DRUG: Androgen Deprivation Therapy (ADT)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Oral Disintegrating Ondansetron Tablet to Reduce Vomiting From Gastroenteritis in a Pediatric Emergency Department
Status: COMPLETED
Conditions: Gastroenteritis|Vomiting|Diarrhea|Dehydration
Interventions: DRUG: Ondansetron Oral Disintegrating Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: A Phase I, Multicenter, Randomized, Double-Blind, Placebo-Controlled HIV-1 Vaccine Trial to Evaluate the Safety and Immunogenicity of rgp120/HIV-1MN (Genentech) in Combination With QS21 Adjuvant and/or Alum in Healthy Adults.
Status: COMPLETED
Conditions: HIV Infections
Interventions: BIOLOGICAL: Aluminum hydroxide|BIOLOGICAL: QS-21|BIOLOGICAL: rgp120/HIV-1MN
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Extended Release Tramadol for Treating Prescription Opioid Withdrawal
Status: COMPLETED
Conditions: Substance Withdrawal Syndrome
Interventions: DRUG: Tramadol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fluorescence Surgery for Sentinel Node Identification in Melanoma
Status: UNKNOWN
Conditions: Melanoma|Lymph Node Metastasis
Interventions: PROCEDURE: Near infra red sentinel node biopsy|DRUG: Indocyanine green|DEVICE: Intraoperative Near-Infrared Imaging System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Complementary Combination Therapy for Cocaine Dependence
Status: COMPLETED
Conditions: Cocaine Dependence
Interventions: DRUG: Doxazosin|DRUG: Modafinil|DRUG: cocaine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: MEBO Ointment and Hyaluronic Acid Gel in the Management of Pain After Free Gingival Graft Harvesting
Status: UNKNOWN
Conditions: Graft Pain|Gingival Recession
Interventions: DRUG: MEBO ointment|DRUG: Hyaluronic Acid gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Maternal Involvement in Pain Management in NICU
Status: COMPLETED
Conditions: Procedural Pain|Mother-Infant Interaction|Infant, Newborn|Stress, Physiological
Interventions: OTHER: Intervention group|OTHER: Standard care group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Treatment of Malignant Peritoneal Mesothelioma (MESOTIP)
Status: RECRUITING
Conditions: Peritoneal Mesothelioma|Peritoneal Carcinomatosis
Interventions: PROCEDURE: PIPAC|DRUG: Cisplatin|DRUG: Pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Total Intravenous Anesthesia With Propofol-remifentanil Versus Inhalational Anesthesia With Sevoflurane on Quality of Recovery in Patients Undergoing Transsphenoidal Surgery for Pituitary Tumor
Status: COMPLETED
Conditions: Pituitary Tumor
Interventions: DRUG: total intravenous anesthesia (TIVA)|DRUG: inhalation anesthesia group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Efficacy, Safety and Pharmacokinetics of SPK-843 in the Treatment of Pulmonary Mycosis
Status: UNKNOWN
Conditions: Cryptococcosis or Aspergillosis Infections
Interventions: DRUG: SPK-843
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Transdermal Nicotine Replacement Therapy (NRT) Activity Through Metabolic Induction
Status: COMPLETED
Conditions: Smoking|Addiction
Interventions: DRUG: Nicabate 21mg transdermal NRT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Combination of Nimotuzumab and Radiotherapy for Recurrent Uterine Cervical Squamous Carcinoma
Status: UNKNOWN
Conditions: Recurrent Cervical Carcinoma|Radiotherapy|Epidermal Growth Factor Receptor|Nimotuzumab|Objective Response Rate|Progression-free Survival|Overall Survival
Interventions: COMBINATION_PRODUCT: Combination of nimotuzumab and radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT