pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: The Effects of Anabolic Steroids and Protease Inhibitors on People Living With HIV/AIDS
Status: COMPLETED
Conditions: HIV|AIDS|Lipodystrophy|Hyperlipidemia
Interventions: PROCEDURE: testosterone injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Simple Bone Cysts in Kids
Status: RECRUITING
Conditions: Bone Cyst
Interventions: PROCEDURE: Curettage with puncture (C & P)|DEVICE: Curette|DEVICE: Vitoss morsels
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Thromboelastography and Conventional Coagulation Tests in Pediatrics With Chronic Liver Disease
Status: NOT_YET_RECRUITING
Conditions: Thromboelastography|Conventional Coagulation Tests|Chronic Liver Disease
Interventions: DIAGNOSTIC_TEST: thromboelastography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Ocriplasmin for Treatment for Symptomatic Vitreomacular Adhesion Including Macular Hole
Status: COMPLETED
Conditions: Vitreomacular Adhesion Including Macular Hole
Interventions: DRUG: Ocriplasmin|OTHER: Sham injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Zolidd One ExHex Dental Implant Compared to Uncoated One ExHex Dental Implant in Subjects With Partial Edentulism
Status: COMPLETED
Conditions: Partial Edentulism
Interventions: DEVICE: Zolidd One ExHex|DEVICE: One ExHex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Effectiveness of Neuromuscular Training in Treatment of Lumbar Spine in Football Players
Status: COMPLETED
Conditions: Injury Leg|Back Pain|Sport Injury|Training Group, Sensitivity|Prevention
Interventions: OTHER: Kinetic Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy With or Without Peripheral Stem Cell Transplant in Treating Men With Previously Untreated Germ Cell Cancer
Status: COMPLETED
Conditions: Mediastinal Cancer|Metastatic Cancer|Testicular Germ Cell Tumor
Interventions: BIOLOGICAL: bleomycin sulfate|BIOLOGICAL: filgrastim|DRUG: cisplatin|DRUG: etoposide|DRUG: ifosfamide|PROCEDURE: bone marrow ablation with stem cell support|PROCEDURE: peripheral blood stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Phase II Study of Clofarabine in Pediatric Acute Lymphoblastic Leukemia (ALL)
Status: COMPLETED
Conditions: Leukemia, Lymphoblastic, Acute, Pediatric
Interventions: DRUG: clofarabine (IV formulation)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endoscopic Stenting Versus Surgical Bypass for Low Bile Duct Obstruction by Cancer of the Pancreatic Head
Status: TERMINATED
Conditions: Pancreatic Cancer
Interventions: PROCEDURE: Surgical bypass|PROCEDURE: Endoscopic stenting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use Of The Dietary Supplement 5-ALA And Its Relationship With Sleep And Mood
Status: COMPLETED
Conditions: Insomnia|Nocturnal Awakening|Irritability|Coping Behavior|Stress
Interventions: DIETARY_SUPPLEMENT: 5-Aminolevulinic Acid (5-ALA)|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose:
Clinical trial: Study to Evaluate the Efficacy of Tacrolimus in Rheumatoid Arthritis Patients Shown Unsuccessful Response to Methotrexate
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Tacrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oxaliplatin, Docetaxel, and Radiation Therapy in Treating Patients With Unresectable Stage II/III or Recurrent NSCLC
Status: TERMINATED
Conditions: Lung Cancer
Interventions: DRUG: docetaxel|DRUG: oxaliplatin|PROCEDURE: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Post-marketing Study of Gabapentin Enacarbil to Evaluate the Effect in Restless Leg Syndrome (RLS) Patients With Moderate Renal Impairment
Status: COMPLETED
Conditions: Restless Legs Syndrome (RLS)
Interventions: DRUG: Gabapentin enacarbil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Two Dietary Programs on Cardiometabolic Risk Factors in Subjects With Metabolic Syndrome
Status: COMPLETED
Conditions: Metabolic Syndrome|Overweight|Obesity|Hypercholesterolemia
Interventions: DIETARY_SUPPLEMENT: UltraMealPlus 360 (Medical food)|OTHER: Low-glycemic-load diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Drain or no Drain After Thyroid Surgery: a Randomized Clinical Trial at Mulago Hospital
Status: COMPLETED
Conditions: Hospital Admission Duration|Postoperative Hematoma Formation|Wound Sepsis
Interventions: PROCEDURE: drain was inserted after thyroid surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The CoCoS Interventional Trial: Caloric Control in Cardiac Surgery Patients
Status: COMPLETED
Conditions: Metabolism and Nutrition Disorders
Interventions: DIETARY_SUPPLEMENT: Nutrition Therapy|DIETARY_SUPPLEMENT: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Single-Ascending Dose Study of AMG 333 in Healthy Subjects and Subjects With Migraines
Status: COMPLETED
Conditions: Migraine
Interventions: DRUG: AMG 333|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Cognitive Function and Glymphatic System in Children With Epilepsy
Status: RECRUITING
Conditions: Epilepsy|Cognitive Dysfunction|Seizure, Epileptic
Interventions: DEVICE: Threshold IMT|DRUG: Antiepileptic medication
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Early MRI Detection of Myocardial Deterioration as a Preventive, Disease Staging, and Prognostic Biomarker in Insulin Resistance
Status: COMPLETED
Conditions: Cardiomyopathies|Insulin Resistance|Non-ischemic Cardiomyopathy|Cardiac Fibrosis|Diabetes
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Leucine-enriched Formulas in Patients With Tumor-induced Sarcopenia
Status: COMPLETED
Conditions: Sarcopenia|Cancer
Interventions: DIETARY_SUPPLEMENT: Standard hypercaloric hyperproteic oral nutritional supplement|DIETARY_SUPPLEMENT: Leucine-enriched hypercaloric hyperproteic oral nutritional supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparative Effectiveness Trial of Transoral Head and Neck Surgery Followed by Adjuvant Radio(Chemo)Therapy Versus Primary Radiochemotherapy for Oropharyngeal Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Oropharyngeal Cancer
Interventions: PROCEDURE: Resection|RADIATION: Radiotherapy|DRUG: Chemotherapy|PROCEDURE: Salvage neck dissection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SARS Coronavirus Vaccine (SARS-CoV)
Status: WITHDRAWN
Conditions: Coronavirus (SARS-CoV)
Interventions: DRUG: Aluminum hydroxide|DRUG: Placebo|BIOLOGICAL: SARS-CoV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Levels of Pigment Epithelium-derived Factor in Patients With Psoriasis.
Status: UNKNOWN
Conditions: Psoriasis
Interventions: OTHER: serum samples and punch skin biopsies
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: DCD IIT: Evaluating the Safety of Utilizing Donor Hearts From Donation After Circulatory Death (DCD) Donors
Status: RECRUITING
Conditions: Organ Transplant
Interventions: OTHER: DBD Donor Heart Transplantation|DEVICE: DCD Donor Heart Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Management of Knee Pain by Cooled Radiofrequency in Classical Anatomical Targets and Revised Targets
Status: UNKNOWN
Conditions: Osteoarthritis, Knee|Pain, Chronic|Analgesia
Interventions: PROCEDURE: Cooled radiofrequency in classical targets (CRF-CT)|PROCEDURE: Cooled radiofrequency in revised targets (CRF-RT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vascular and Metabolic Effects of Fenofibrate/Omega vs Fenofibrate
Status: COMPLETED
Conditions: Hypertriglyceridemia
Interventions: DRUG: placebo|DRUG: fenofibrate/omega|DRUG: fenofibrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effects of Latanoprost, Bimatoprost and Travoprost in Patients With Latanoprost-resistant Glaucoma
Status: UNKNOWN
Conditions: Ocular Hypertension|Primary Glaucoma
Interventions: DRUG: Latanoprost, bimatoprost, travoprost|DRUG: travoprost, latanoprost and bimatoprost
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial to Evaluate Genomic Expression Profiles to Direct Preoperative Chemotherapy in Early Stage Breast Cancer
Status: TERMINATED
Conditions: Early-Stage Breast Cancer
Interventions: DRUG: Doxorubicin/Cyclophosphamide (AC) or Docetaxel/Cyclophosphamide (TC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD6234 After Repeat Dose Administration in Participants Who Are Overweight or Obese
Status: RECRUITING
Conditions: Healthy Participants
Interventions: DRUG: AZD6234|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Cardio- and Renoprotective Effect of Remote Ischemic Preconditioning in Patients Undergoing Percutaneous Coronary Intervention
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: OTHER: Remote Ischemic Pre-Conditioning
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effects of Dark Chocolate on Blood Pressure in Individuals With Mildly Elevated Blood Pressure
Status: COMPLETED
Conditions: Blood Pressure
Interventions: DIETARY_SUPPLEMENT: Dark chocolate|OTHER: Dietary counselling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Effect of Hydroxychloroquine in COVID-19 Positive Pregnant Women
Status: WITHDRAWN
Conditions: COVID-19|SARS-CoV-2|Pregnant Women|Hydroxychloroquine
Interventions: DRUG: hydroxychloroquine sulfate 200 MG|DRUG: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sorafenib in Combination With Irinotecan in Metastatic Colorectal Cancer Patients With KRAS Mutated Tumors
Status: COMPLETED
Conditions: Metastatic Colorectal Cancer Patients With KRAS Mutated Tumors
Interventions: DRUG: Sorafenib and irinotecan combination|DRUG: Sorafenib monotherapy|DRUG: Irinotecan monotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tailored Response to Psychiatric Comorbidity to Improve HIV Care Engagement in the United States
Status: COMPLETED
Conditions: HIV/AIDS|Depression|Anxiety|Post-traumatic Stress Disorder|Substance Use Disorders
Interventions: BEHAVIORAL: Adapted Common Elements Treatment Approach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I/II Study to Evaluate Nab-paclitaxel in Substitution of CPT11 or Oxaliplatin in FOLFIRINOX Schedule as First Line Treatment in Metastatic Pancreatic Cancer
Status: COMPLETED
Conditions: Metastatic Pancreatic Cancer
Interventions: DRUG: Paclitaxel bound albumine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Using the PHQ-9 and GAD-7 as Feedback Instruments in Brief Psychotherapy
Status: COMPLETED
Conditions: Depressive Symptoms|Anxiety States, Neurotic
Interventions: BEHAVIORAL: Continuous Client Feedback|BEHAVIORAL: Continuous Self Feedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Primary Vaccination Study With GSK Biologicals' Pneumococcal Vaccine in Healthy Infants in Vietnam
Status: COMPLETED
Conditions: Infections, Streptococcal|Streptococcus Pneumoniae Vaccines
Interventions: BIOLOGICAL: Synflorix™( GSK1024850A)|BIOLOGICAL: Infanrix hexa™
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of INCB050465 in Participants With Autoimmune Hemolytic Anemia
Status: COMPLETED
Conditions: Autoimmune Hemolytic Anemia
Interventions: DRUG: Parsaclisib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lamotrigine in the Treatment of Binge Eating Disorder Associated With Obesity
Status: COMPLETED
Conditions: Binge Eating Disorder|Obesity
Interventions: DRUG: Lamotrigine|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Acetyl Salicylic Acid and Terbutalin in Assisted Reproductive Techniques (ART)
Status: COMPLETED
Conditions: Reproductive Techniques, Assisted
Interventions: DRUG: Acetyl Salicylic Acid and Terbutalin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of an Anxiety Intervention for Latino/Latina/Hispanic Older Adults With Cancer and Their Caregivers
Status: RECRUITING
Conditions: Cancer Patients|Care Givers
Interventions: OTHER: Managing Anxiety from Cancer (MAC)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Central Nervous System Infections in Denmark
Status: RECRUITING
Conditions: Central Nervous System Infections|Bacterial Meningitis|Viral Meningitis|Aseptic Meningitis|Encephalitis|Brain Abscess|Neuroborreliosis|Neurosyphilis|Lyme Disease|Tertiary Syphilis|Cerebral Abscess|Meningitis
Interventions: OTHER: Community-acquired CNS infections
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Supracondylar Distal Femur Fractures and Abaloparatide
Status: WITHDRAWN
Conditions: Femoral Fractures
Interventions: DRUG: Abaloparatide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Single-Dose Islatravir in Moderate Hepatic Impairment (MK-8591-030)
Status: COMPLETED
Conditions: Human Immunodeficiency Virus (HIV) Infection
Interventions: DRUG: Islatravir
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Leukotriene D4 Nasal Provocation Test in Allergic Rhinitis
Status: COMPLETED
Conditions: Allergic Rhinitis|Asthma
Interventions: DRUG: leukotriene D4|DRUG: histamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Evaluate the Safety and Efficacy of Zilganersen (ION373) in Patients With Alexander Disease (AxD)
Status: ENROLLING_BY_INVITATION
Conditions: Alexander Disease
Interventions: DRUG: zilganersen|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Multi-Site Trial of MS INFoRm (Fatigue Management Resource)
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: BEHAVIORAL: MS INFoRm|BEHAVIORAL: Usual Care Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Aliskiren in Combination With Losartan Compared to Losartan on the Regression of Left Ventricular Hypertrophy in Overweight Patients With Essential Hypertension
Status: COMPLETED
Conditions: Hypertension|Left Ventricular Hypertrophy|Overweight
Interventions: DRUG: Aliskiren 150/300 mg|DRUG: Losartan 50/100 mg|DRUG: Aliskiren placebo|DRUG: Losartan 50/100 mg placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Impact of Implementing a Nursing-driven Clinical Pathway for Inpatient Management of Children With Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: OTHER: Nursing-driven clinical pathway for management of inpatient asthma
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Music on Pain and Anxiety in Patients Receiving Chemotherapy During COVID-19
Status: COMPLETED
Conditions: Cancer|Chemotherapy
Interventions: OTHER: Listening Music|OTHER: Not Listening Music
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: An Efficacy and Safety Study of Telaprevir in Patients Infected With Both Chronic Hepatitis C Virus (HCV-1) and Human Immunodeficiency Virus (HIV-1)
Status: COMPLETED
Conditions: Chronic Hepatitis C
Interventions: DRUG: Telaprevir|DRUG: Ribavirin|DRUG: Pegylated-Interferon-alfa-2a
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Harm Reduction Program For Informal PrEP Users In A Community-based Setting (seguiPrEP)
Status: UNKNOWN
Conditions: HIV/AIDS|HIV Infections|Sexually Transmitted Diseases|Vaccination|Adherence, Medication|Side Effect of Drug|Preexposure Prophylaxis
Interventions: BEHAVIORAL: Harm reduction of informal PrEP use|OTHER: PrEP follow up based on point of care testing
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: AV-GBM-1 vs Control as Adjunctive Therapy Following Surgery and RT/TMZ in Newly Diagnosed GBM
Status: NOT_YET_RECRUITING
Conditions: Primary Glioblastoma
Interventions: BIOLOGICAL: AV-GBM-1|BIOLOGICAL: Autologous monocytes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Melphalan, Prednisone, and Thalidomide or Lenalidomide in Treating Patients With Newly Diagnosed Multiple Myeloma
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Myeloma
Interventions: OTHER: Laboratory Biomarker Analysis|DRUG: Lenalidomide|DRUG: Melphalan|DRUG: Prednisone|OTHER: Quality-of-Life Assessment|DRUG: Thalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nicotinamide Adenine Dinucleotide and Skeletal Muscle Metabolic Phenotype
Status: UNKNOWN
Conditions: Aging
Interventions: DIETARY_SUPPLEMENT: Nicotinamide Riboside|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Regimen Education and Messaging in Diabetes (REMinD)
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Medication Adherence
Interventions: BEHAVIORAL: UMS Strategy|BEHAVIORAL: SMS Text Messaging
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study of Vintafolide (MK-8109, EC145) in Participants With Advanced Ovarian and Endometrial Cancers (MK-8109-007, EC-FV-02)
Status: COMPLETED
Conditions: Ovarian Cancer|Endometrial Cancer
Interventions: DRUG: Vintafolide|DRUG: Ertafolide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neuromodulation for Exercise Adherence
Status: RECRUITING
Conditions: Executive Dysfunction|Poor Exercise Adherence
Interventions: DEVICE: rTMS|DEVICE: Sham|OTHER: No intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nutrition, Body Composition, and Sleep
Status: COMPLETED
Conditions: Sleep|Body Composition|Strength|Insulin Sensitivity|Energy Expenditure
Interventions: DIETARY_SUPPLEMENT: Whey protein|DIETARY_SUPPLEMENT: Omega-3 fatty acids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Assessing Outpatient 'Day Procedure' for Second-trimester Medical Abortion at Two Public Sector Hospitals in Nepal
Status: COMPLETED
Conditions: Abortion in Second Trimester
Interventions: DRUG: Mifepristone + Misoprostol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Endocrine Therapy +/- the PI3K Inhibitor Inavolisib in HER2+, HR+, PIK3CA Mutant Early Breast Cancer
Status: RECRUITING
Conditions: HER2-positive Breast Cancer
Interventions: DRUG: Inavolisib|DRUG: PHESGO|DRUG: Endocrine therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Immune Responses After Vaccination With an Investigational RNA-based Vaccine Against Malaria
Status: ACTIVE_NOT_RECRUITING
Conditions: Malaria
Interventions: BIOLOGICAL: BNT165b1|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Pilot Study to Compare the Pharmacokinetics Parameters in Plasma and Intracellular of Raltegravir Administered Once a Day in Adult Patients Infected With HIV
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Raltegravir
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BOTOX in Men With Prostate Cancer With Lower Urinary Tract Symptoms(LUTS)/Benign Prostatic Hyperplasia (BPH)
Status: WITHDRAWN
Conditions: Prostate Cancer|Benign Prostatic Hyperplasia|Enlarged Prostate With Lower Urinary Tract Symptoms (LUTS)
Interventions: DRUG: BOTOX
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: TheraBracelet Phase I
Status: COMPLETED
Conditions: Hand Function|Stroke|Upper Extremity|Hemiparesis|Cerebrovascular Accident|Stroke Rehabilitation
Interventions: DEVICE: Real Stimulation|DEVICE: Sham Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Study of HBI-3000
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DRUG: HBI-3000|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of MK-2206 + Endocrine Treatment in Patients With Hormone Receptor Positive Breast Cancer
Status: WITHDRAWN
Conditions: Metastatic Breast Cancer
Interventions: DRUG: MK-2206|DRUG: Exemestane|DRUG: Goserelin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness & Safety of Ovine Enoxaparin Sodium to Originator Enoxaparin in Non-ST-Segment Elevation Acute Coronary Syndrome (NSTEACS) Patients: a Multicenter, Non-randomized, Open-label, Non-inferiority Trial
Status: RECRUITING
Conditions: Safety Issues|Effect of Drug
Interventions: DRUG: Enoxaparin sodium injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Hepatitis C in Hemophilic Patients With HIV
Status: COMPLETED
Conditions: HIV Infections|Hepatitis C|Hemophilia
Interventions: DRUG: Peginterferon alfa-2a|DRUG: Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Vonapanitase (PRT-201) Administered Immediately After Radiocephalic Arteriovenous Fistula(AVF) Creation in Patients With Chronic Kidney Disease (CKD) (PATENCY-2)
Status: COMPLETED
Conditions: Chronic Kidney Disease
Interventions: DRUG: Vonapanitase|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Post-stroke Epilepsy: Primary Prophylaxis Study
Status: UNKNOWN
Conditions: Middle Cerebral Artery Stroke
Interventions: DRUG: Levetiracetam Oral Product|DRUG: Perampanel Oral Product|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Men With Fibromyalgia or Chronic Widespread Pain - Effect of Exercise on Symptoms and Body Functions
Status: COMPLETED
Conditions: Fibromyalgia|Pain
Interventions: BEHAVIORAL: Graded strength resistance training program|BEHAVIORAL: Temperate pool exercise program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of AN2728 Topical Ointment to Treat Adolescents With Atopic Dermatitis
Status: COMPLETED
Conditions: Dermatitis, Atopic
Interventions: DRUG: AN2728 Topical Ointment, 2% QD|DRUG: AN2728 Topical Ointment, 0.5% QD|DRUG: AN2728 Topical Ointment, 2% BID|DRUG: AN2728 Topical Ointment, 0.5% BID
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: NC-6004(Nanoplatin) and Gemcitabine to Treat Pancreatic Cancer in Asia
Status: COMPLETED
Conditions: Locally Advanced and Metastatic Pancreatic Cancer
Interventions: DRUG: Nanoplatin (NC-6004) and Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of Extended 2-dose Regimens of 9-valent Human Papillomavirus (9vHPV) Vaccine (V503-069)
Status: ACTIVE_NOT_RECRUITING
Conditions: Papillomavirus Infections
Interventions: BIOLOGICAL: 9vHPV vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: First In Human, Single Escalating Oral Dose Study Of PF-06882961 In Healthy Adult Subjects
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: PF-06882961|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of AZD3152 Intramuscular Injection or Intravenous Infusion in Healthy Japanese Adult Participants
Status: ACTIVE_NOT_RECRUITING
Conditions: COVID-19, SARS-CoV-2
Interventions: BIOLOGICAL: AZD3152 (Cohort 1)|BIOLOGICAL: Placebo (Cohort 1)|BIOLOGICAL: AZD3152 (Cohort 2)|BIOLOGICAL: Placebo (Cohort 2)|BIOLOGICAL: AZD3152 (Cohort 3)|BIOLOGICAL: Placebo (Cohort 3)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Training With Exergame and Treadmill on Executive Function and Dual-task Performance
Status: COMPLETED
Conditions: Parkinson's Disease|Stroke
Interventions: OTHER: Dual-task training|OTHER: Treadmill training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: EMG Biofeedback Training to Improve Balance in Individuals With Multiple Sclerosis
Status: NOT_YET_RECRUITING
Conditions: Multiple Sclerosis
Interventions: DEVICE: Integrated Dual-task EMG Biofeedback Training (EMG-BF)|BEHAVIORAL: Traditional Balance Exercise Training (BAL-EX)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Neuromuscular Electrostimulation on Scapular Stability
Status: COMPLETED
Conditions: Adult Female Handball Player
Interventions: OTHER: Therapeutic physical exercise program for scapulo-humeral stabilitation|OTHER: Therapeutic physical exercise program for scapulo-humeral stabilitation + electrostimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety Study of Bile Acid to Treat Hypercholesteremia
Status: UNKNOWN
Conditions: Hypercholesterolemia
Interventions: DRUG: AHRO-001
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Resilient, Empowered, Active Living: REAL Diabetes Study
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1|Diabetes Mellitus, Type 2
Interventions: BEHAVIORAL: Resilient, Empowered, Active Living with Diabetes|BEHAVIORAL: Information Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Peripheral Vascular Disease and Nerve Stimulation
Status: COMPLETED
Conditions: Critical Limb Ischaemia|Claudication|Ulcers|Varicose Veins|Post Angioplasty
Interventions: DEVICE: geko™ electrical stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigating Mechanism of Action of DAC HYP in the Treatment of High-Inflammatory Multiple Sclerosis (MS)
Status: COMPLETED
Conditions: Multiple Sclerosis|Multiple Sclerosis, Relapsing-Remitting
Interventions: BIOLOGICAL: DAC-HYP
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vaccine Therapy and Cyclophosphamide in Treating Patients With Stage II-III Breast or Stage II-IV Ovarian, Primary Peritoneal, or Fallopian Tube Cancer
Status: COMPLETED
Conditions: Recurrent Breast Carcinoma|Recurrent Fallopian Tube Carcinoma|Recurrent Ovarian Carcinoma|Recurrent Primary Peritoneal Carcinoma|Stage IIA Breast Cancer|Stage IIA Fallopian Tube Cancer|Stage IIA Ovarian Cancer|Stage IIB Breast Cancer|Stage IIB Fallopian Tube Cancer|Stage IIB Ovarian Cancer|Stage IIC Fallopian Tube Cancer|Stage IIC Ovarian Cancer|Stage IIIA Breast Cancer|Stage IIIA Fallopian Tube Cancer|Stage IIIA Ovarian Cancer|Stage IIIA Primary Peritoneal Cancer|Stage IIIB Breast Cancer|Stage IIIB Fallopian Tube Cancer|Stage IIIB Ovarian Cancer|Stage IIIB Primary Peritoneal Cancer|Stage IIIC Breast Cancer|Stage IIIC Fallopian Tube Cancer|Stage IIIC Ovarian Cancer|Stage IIIC Primary Peritoneal Cancer|Stage IV Fallopian Tube Cancer|Stage IV Ovarian Cancer|Stage IV Primary Peritoneal Cancer
Interventions: DRUG: Cyclophosphamide|OTHER: Laboratory Biomarker Analysis|BIOLOGICAL: Multi-epitope Folate Receptor Alpha Peptide Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acupuncture and Nausea/Vomiting in Pediatric Patients
Status: COMPLETED
Conditions: Postoperative Vomiting and Nausea
Interventions: DEVICE: Acupuncture Needle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Dupuytren´s Disease Study. Primary Disease, MCP Joint, Xiapex, PNF
Status: COMPLETED
Conditions: Dupuytren Contracture
Interventions: DRUG: Xiapex|PROCEDURE: Needle aponeurotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Relative Bioavailability Study of One Amlodipine 10mg Tablet and One Rosuvastatin 20mg Tablet to Two Fixed Dose Combinations of Amlodipine (10mg) and Rosuvastatin (20mg) in Healthy Subjects Under Fasting Conditions
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Amlodipine+Rosuvastatin|DRUG: GSK3074477 FDC - 1|DRUG: GSK3074477 FDC - 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fat and Sugar Metabolism During Exercise, With and Without L-carnitine in Patients With Carnitine Transporter Deficiency
Status: COMPLETED
Conditions: Carnitine Transporter, Plasma-membrane, Deficiency of
Interventions: DIETARY_SUPPLEMENT: Break in L-carnitine treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Heat-Activated Target Therapy of Local-Regional Relapse in Breast Cancer Patients
Status: WITHDRAWN
Conditions: Breast Cancer
Interventions: DRUG: ThermoDox (Thermally Sensitive Liposomal Doxorubicin)|RADIATION: Radiation Therapy|DEVICE: Superficial Hyperthermia
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Intentional Delivery in Women With Preterm and Prelabour Rupture of the Membranes
Status: TERMINATED
Conditions: Fetal Membranes, Premature Rupture
Interventions: PROCEDURE: Induction of delivery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neurofeedback-EEG Rehabilitation Protocol on Motor Recovery in the Subacute Phase Post-stroke (CUSTOM-NF-STROKE)
Status: RECRUITING
Conditions: Cerebrovascular Accident
Interventions: BEHAVIORAL: Neurofeedback procedure|OTHER: Fugl-Meyer test|OTHER: Intrinsic Motivation Inventory questionnaire|OTHER: Hospital Anxiety and Depression Scale|OTHER: State Anxiety Inventory scores|OTHER: Acceptability questionnaire (BCI-ACCEPT)|OTHER: System Usability Scale questionnaire|OTHER: NASA Task Load Index questionnaire|OTHER: Agency test|OTHER: Visual and Kinesthetic Imagery Questionnaire|OTHER: Technology Locus of Control Assessment Questionnaire|OTHER: POSITIVE AFFECTIVITY AND NEGATIVE AFFECTIVITY SCALE|OTHER: Self-questionnaire: OCEAN of the five major factors of per- sound (or Big Five model)|OTHER: Feeling VAS scores|OTHER: Reaching Performance Scale
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Developing a Portable Therapeutic Baby Nest for Newborns and Evaluation During Venous Blood Collection
Status: COMPLETED
Conditions: Pain|Newborn|Comfort
Interventions: PROCEDURE: Venous blood collection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Clinical Evaluation of HRV Biofeedback in Functional Neurological Disorders Compared to Placebo
Status: NOT_YET_RECRUITING
Conditions: Functional Neurological Disorder
Interventions: OTHER: Heart rate variability Biofeedback [HRV-BFB]|OTHER: Pseudo HRV-BFB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Relative Bioavailability Study of Sertraline HCl 100 mg Tablets Under Non-fasting Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Sertraline HCl 100 mg tablets, single dose|DRUG: Zoloft® 100 mg tablets, single dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Efficacy and Safety Study of MCI-186 for Treatment of Amyotrophic Lateral Sclerosis (ALS) Who Met Severity Classification III
Status: COMPLETED
Conditions: Amyotrophic Lateral Sclerosis (ALS)
Interventions: DRUG: MCI-186|DRUG: Placebo of MCI-186
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of empagliFlozin on Platelet Function profilEs in diabetiC patienTs - The EFFECT Study.
Status: COMPLETED
Conditions: Platelet Dysfunction Due to Drugs
Interventions: DRUG: SGLT2 inhibitor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Single Time-Point Study to Evaluate the ConforMIS iTotal (PS) Knee Replacement System Versus Off-the-Shelf
Status: TERMINATED
Conditions: Osteoarthritis, Knee
Interventions: DEVICE: iTotal PS Knee Replacement System|DEVICE: Off-the-Shelf Knee Replacement System
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Pilot Study: a Non-opioid Technique for Postoperative Adenoidectomy Pain Relief in Pediatric Patients
Status: COMPLETED
Conditions: Adenoid Hypertrophy
Interventions: DRUG: Dextromethorphan|DRUG: Acetaminophen|DRUG: Dexmedetomidine|DRUG: Ketamine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety and Efficacy of Two Different Dosing Schedules of Pembrolizumab (MK-3475) Compared to Ipilimumab in Participants With Advanced Melanoma (MK-3475-006/KEYNOTE-006)
Status: COMPLETED
Conditions: Melanoma
Interventions: BIOLOGICAL: Pembrolizumab|BIOLOGICAL: Ipilimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of One-to-one Service on the Continuation and Satisfaction of Contraceptive Use.
Status: UNKNOWN
Conditions: Contraception Behavior|Contraceptive Usage
Interventions: DRUG: Compound Norethisterone Enanthate Injection|OTHER: One-to-one Service|OTHER: Family Planning Service
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: PO vs. IV Acetaminophen Given Perioperatively for 24 hr Post-op Pain Control Following Total Hip or Knee Replacement
Status: COMPLETED
Conditions: Post-op Pain
Interventions: DRUG: Oral acetaminophen|DRUG: IV acetaminophen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Clinical Study Conducted in Multiple Centers Evaluating Escalating Doses of Veliparib in Combination With Capecitabine and Radiation in Patients With Locally Advanced Rectal Cancer
Status: COMPLETED
Conditions: Locally Advanced Rectal Cancer
Interventions: DRUG: veliparib|DRUG: capecitabine|RADIATION: radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Everolimus and Bendamustine Hydrochloride in Treating Patients With Relapsed or Refractory Hematologic Cancer
Status: COMPLETED
Conditions: Recurrent Adult Diffuse Large Cell Lymphoma|Recurrent Adult Hodgkin Lymphoma|Recurrent Grade 1 Follicular Lymphoma|Recurrent Grade 2 Follicular Lymphoma|Recurrent Grade 3 Follicular Lymphoma|Recurrent Mantle Cell Lymphoma|Refractory Chronic Lymphocytic Leukemia|Multiple Myeloma
Interventions: DRUG: everolimus|DRUG: bendamustine hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gases Humidification During Noninvasive Ventilation : Heat and Moisture Exchanger or Heated Humidifier ?
Status: TERMINATED
Conditions: Acute Lung Injury|Pneumonia|Chronic Obstructive Pulmonary Disease|Acute Heart Failure
Interventions: DEVICE: heated humidifier (device)|DEVICE: Heat and moisture exchanger (device)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I/II Trial of AEZS-108 in Urothelial Cancer Patients Who Failed Platinum-chemotherapy
Status: TERMINATED
Conditions: Urothelial Carcinoma
Interventions: DRUG: AEZS-108|DRUG: AEZS-108 at MTD
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ALLN-346 Single Ascending Dose (SAD) Study in Healthy Volunteers
Status: COMPLETED
Conditions: Hyperuricemia
Interventions: DRUG: ALLN-346|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of PD-1 Inhibitors Combined With Fruquintinib and Chemotherapy in First-line Treatment of HER2-negative Advanced G/GEJ Cancer
Status: RECRUITING
Conditions: Gastric Cancer/Adenocarcinoma of Esophagogastric Junction
Interventions: DRUG: Fruquintinib、Nivolumab、Sintilimab、Oxaliplatin、Teysuno、Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Extension Block Technique Versus Splinting in Mallet Finger Fracture.
Status: COMPLETED
Conditions: Mallet Finger
Interventions: PROCEDURE: Conservative treatment with splinting for 6 weeks.|PROCEDURE: Operative treatment with extension block technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: 3-midline-ports Cholecystectomy
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: PROCEDURE: 3-midline-ports laparoscopic cholecystectomy|PROCEDURE: 3-midline-ports laparoscopic cholecystectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neurobiology of Anorexia and Bulimia Nervosa
Status: COMPLETED
Conditions: Anorexia Nervosa|Bulimia Nervosa
Interventions: OTHER: Imaging|BEHAVIORAL: fast|BEHAVIORAL: regulated meals
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of Efficacy of Intraligamentary Anesthesia for Mandibular Molar Extractions
Status: RECRUITING
Conditions: Anesthesia, Local
Interventions: PROCEDURE: Mandibular Molar Extraction Under Local Anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cardiometabolic Screening Program
Status: RECRUITING
Conditions: Breast Cancer|Early-stage Breast Cancer
Interventions: OTHER: Prescreening|OTHER: Screening and Enrollment|BEHAVIORAL: Baseline|BEHAVIORAL: Interpret BMI|OTHER: Interpret HbA1c|OTHER: Interpret lipid panel and assess other risk factors|BEHAVIORAL: Assess 10 year risk of cardiovascular event|BEHAVIORAL: Recommendations|BEHAVIORAL: Follow-Up
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Study Testing the Biologic Activity and Safety of a Immunotherapeutic in Patients With Newly Diagnosed Advanced Stage Kidney Cancer in Combination With a Marketed Renal Cell Carcinoma Treatment
Status: COMPLETED
Conditions: Renal Cell Carcinoma
Interventions: BIOLOGICAL: AGS-003|DRUG: Sunitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cardiac Biofeedback, Mindfulness, and Inner Resources Mobilization Interventions on Performances of Medical Students
Status: COMPLETED
Conditions: Stress, Psychological|Stress|Stress, Physiological|Exam Stress|Performance|Mindfulness|Communication|Medical Education
Interventions: OTHER: Cardiac biofeedback|OTHER: Mindfulness|OTHER: Resources mobilization|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER