pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Integrative Cardiac Health Project Cognitive-Behavior Therapy for Insomnia
Status: TERMINATED
Conditions: Insomnia|Cardiovascular Risk Factor
Interventions: BEHAVIORAL: Cognitive-Behavior Therapy for Insomnia (CBT-I)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Early CRRT InTerventions in Patients With ECMO(ELITE)
Status: COMPLETED
Conditions: Cardiogenic Shock
Interventions: DEVICE: Simultaneous CRRT|DEVICE: Conventional-indication CRRT|DRUG: Esmolol|DRUG: Standard care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Irinotecan, 5-Fluorouracil and Leucovorin With or Without Iressa in the Treatment of Metastatic Colorectal Cancer
Status: WITHDRAWN
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: Iressa (Gefitinib)|DRUG: Irinotecan|DRUG: 5Fluorouracil|DRUG: Leucovorin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Single Arm, Open-label Clinical Trial to Evaluate the Efficacy and Safety of Maintenance Treatment With Capecitabine Plus Cetuximab in Metastatic Colorectal Cancer
Status: UNKNOWN
Conditions: Colorectal Neoplasms
Interventions: OTHER: maintenance treatment with capecitabine plus cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Orchidopexy Randomized Clinical Assessment
Status: RECRUITING
Conditions: Unilateral Cryptorchidism
Interventions: PROCEDURE: Single-stage Fowler-Stephens orchidopexy (FSO)|PROCEDURE: Two-stage Fowler-Stephens orchidopexy (FSO)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: NATO Litter: Fluid Immersion System (FIS) Versus Traditional Mattress for Pressure Dispersion
Status: COMPLETED
Conditions: Pressure Distribution|Military Litters|Peak Pressure Index|Total Surface Area|Tissue Perfusion
Interventions: OTHER: NATO WELP combination|OTHER: NATO FIS combination|OTHER: RAVEN WELP combination|OTHER: RAVEN FIS combination
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Trial to Assess the Ocular Safety of Vorapaxar (SCH 530348) in Participants With Atherosclerosis (Study P05183)
Status: COMPLETED
Conditions: Atherosclerosis|Ischemia|Myocardial Infarction|Cerebrovascular Accident
Interventions: DRUG: Vorapaxar 2.5 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: SBRT Compared With IMRT Concurrently With Chemotherapy in Treating Patients With LS-SCLC
Status: UNKNOWN
Conditions: Small Cell Lung Cancer
Interventions: RADIATION: SBRT|RADIATION: IMRT|DRUG: EP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Tocilizumab as Monotherapy or in Combination With DMARDs in Patients With Moderate to Severe Active Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: tocilizumab [RoActemra/Actemra]
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HIBOC = Hepatic Imaging Biomarkers in Obese Children
Status: NOT_YET_RECRUITING
Conditions: Elastography|Shear Wave Elastography|Shear Wave Dispersion|Attenuation Imaging|Child Obesity|Metabolic Disease|Metabolic and Genetic Disorder Affecting the Liver|Fibrosis, Liver|Diagnosis|Inflammation; Liver|Steatosis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Prevalence of HPV Transmission During Medically Assisted Procreation Procedures
Status: COMPLETED
Conditions: Human Papillomavirus (HPV)|Medically Assisted Procreation (MAP)|Infertility
Interventions: OTHER: Systematic HPV DNA assay in semen and cervicovaginal scrape|OTHER: Systematic HPV DNA cervicovaginal scrape|OTHER: systematic HPV Status in newborns in case of pregnancy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: A Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ION904
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: ION904|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Topical Thalidomide to Treat Chronic Graft-Versus-Host-Disease Related Stomatitis
Status: TERMINATED
Conditions: Graft-versus-Host Disease|Stomatitis
Interventions: DRUG: Thalidomide Gel|DRUG: Placebo Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Colonization of the Female Urethra With Mycoplasma Hominis, Ureaplasma Urealyticum, Chlamydia Trachomatis, or Neisseria Gonorrhea in Patients With Lower Urinary Tract Symptoms
Status: COMPLETED
Conditions: Overactive Bladder Syndrome
Interventions: PROCEDURE: retrospective data analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Optimization of Mass Drug Administration With Existing Drug Regimens for Lymphatic Filariasis and Onchocerciasis
Status: COMPLETED
Conditions: Lymphatic Filariasis|Soil Transmitted Helminth Infections
Interventions: DRUG: Albendazole (annual)|DRUG: Diethylcarbamazine (annual)|DRUG: Albendazole (semiannual)|DRUG: Diethylcarbamazine (semiannual)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: SPECT/CT in Measuring Lung Function in Patients With Cancer Undergoing Radiation Therapy
Status: COMPLETED
Conditions: Lung Carcinoma|Malignant Neoplasm
Interventions: DIAGNOSTIC_TEST: SPECT/CT|PROCEDURE: Single Photon Emission Computed Tomography|RADIATION: Technetium Tc-99m Albumin Aggregated|DRUG: Technetium Tc-99m DTPA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety, Tolerance, and Pharmacokinetics of Single Oral Doses of BI 201335 NA and Bioavailability in Healthy Male Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BI 201335 NA|DRUG: Placebo solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Volumetric Modulated Arc Therapy (VMAT) for Brain Metastases
Status: ACTIVE_NOT_RECRUITING
Conditions: Brain Metastases
Interventions: RADIATION: whole brain radiotherapy (WBRT) and a simultaneous integrated boost (SIB) using volumetric modulated arc therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Losartan on Insulin Sensitivity and Secretion in Type 2 Diabetes and Nephropathy
Status: COMPLETED
Conditions: Type 2 Diabetes|Diabetic Nephropathy
Interventions: DRUG: losartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ARTEMIS-002: HS-20093 in Patients With Relapsed or Refractory Osteosarcoma and Other Sarcomas
Status: RECRUITING
Conditions: Osteosarcoma|Sarcoma
Interventions: DRUG: HS-20093
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Xerosis and Use of Topical Moisturizer
Status: ACTIVE_NOT_RECRUITING
Conditions: Xerosis Due to Atopic Dermatitis
Interventions: OTHER: Cetaphil Pro Eczema moisturizer|BEHAVIORAL: Electronic interaction|BEHAVIORAL: GPSkin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Blood Brain Barrier (BBB) Disruption Using Exablate Focused Ultrasound With Doxorubicin for Treatment of Pediatric DIPG
Status: RECRUITING
Conditions: Brain Tumor
Interventions: DEVICE: Exablate|DRUG: Doxorubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: A Study to Evaluate the Effectiveness of Laser-Ablated Implant-Abutments to Promote Tissue Healing
Status: COMPLETED
Conditions: Jaw, Edentulous, Partially
Interventions: DEVICE: Dental implant-abutments
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectivity and Safety of Combination Cream of Salicylic Acid, Aqua Posae Filiformis, Niacinamide, Lipohydroxy Acid, Procerad and Zinc PCA
Status: ACTIVE_NOT_RECRUITING
Conditions: Acne Vulgaris
Interventions: DRUG: Combination Cream|DRUG: Adapalene 0,1% cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Adiposity Related hypErTension (TARGET)
Status: COMPLETED
Conditions: Hypertension|Abdominal Obesity|Metabolic Syndrome
Interventions: DRUG: Aliskiren|DRUG: Moxonidine|DRUG: Hydrochlorothiazide|DRUG: Placebo (for aliskiren)|DRUG: Placebo (for moxonidine and hydrochlorothiazide)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Restoring Hemodynamic Stability Using Targeted Epidural Spinal Stimulation Following Spinal Cord Injury
Status: UNKNOWN
Conditions: Spinal Cord Injuries
Interventions: DEVICE: Targeted Epidural Spinal Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Duloxetine for Postoperative Pain of Laparoscopic Cholecystectomy
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: DRUG: Duloxetine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Calcineurin Inhibitor-Free GVHD Prevention Regimen After Related Haplo PBSCT
Status: COMPLETED
Conditions: Non-Hodgkin's Lymphoma|Acute Leukemia in Remission|Chronic Myeloid Leukemia|Primary Myelofibrosis|Chronic Myelomonocytic Leukemia|Myelodysplastic Syndromes|Hodgkin Lymphoma|Multiple Myeloma
Interventions: DRUG: Fludarabine|DRUG: Busulfan|DRUG: Cyclophosphamide|RADIATION: Total body irradiation (TBI)|PROCEDURE: Peripheral Blood Hematopoietic Cell Transplantation (HCT)|DRUG: Sirolimus (SIR)|DRUG: Mycophenolate mofetil (MMF)|DRUG: Granulocyte-colony stimulating factor (G-CSF)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study on Antiretroviral Therapy (ART) Naïve Patients On Different Regimens to Treat Hiv (NORTHIV)
Status: COMPLETED
Conditions: HIV
Interventions: DRUG: Lopinavir ritonavir|DRUG: Atazanavir ritonavir|DRUG: Efavirenz
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Determine Safety and Efficacy of (REMD-477) in Controlling Hyperglycemia Due to Copanlisib
Status: TERMINATED
Conditions: Hyperglycemia Drug Induced
Interventions: BIOLOGICAL: REMD-477
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Interactive Games on Children Receiving Intravenous Injection
Status: UNKNOWN
Conditions: Pain|Fear|Emotions
Interventions: DEVICE: The somatosensory interactive game for preschool children|DEVICE: A VR (virtual reality) game for school-age children
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sentinel Lymph Node (SLN) in Colorectal Carcinoma (CRC) With a Near-infrared (NIR)-Dye
Status: COMPLETED
Conditions: Sentinel Lymph Node|Colorectal Cancer|Metastasis
Interventions: PROCEDURE: Near-Infrared (NIR) dye Indocyanin Green (ICG)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Evaluate the Safety and Efficacy of Pregabalin in Patients With Painful Diabetic Peripheral Neuropathy.
Status: COMPLETED
Conditions: Diabetic Neuropathy, Painful
Interventions: DRUG: Pregabalin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of ZW25 (Zanidatamab) in Patients With Advanced HER2-expressing Cancers
Status: ACTIVE_NOT_RECRUITING
Conditions: HER2-expressing Cancers
Interventions: DRUG: ZW25 (Zanidatamab)|DRUG: Paclitaxel|DRUG: Capecitabine|DRUG: Vinorelbine|DRUG: Tucatinib|DRUG: Tucatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: T Cell Receptor Immunotherapy Targeting NY-ESO-1 for Patients With NY-ESO-1 Expressing Cancer
Status: COMPLETED
Conditions: Melanoma|Meningioma|Breast Cancer|Non-Small Cell Lung Cancer|Hepatocellular Cancer
Interventions: BIOLOGICAL: Anti-NY ESO-1 mTCR PBL|DRUG: Cyclophosphamide|DRUG: Fludarabine|DRUG: Aldesleukin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Intervention Mapping Approach to Closing the Gap in Maternal OUD and Infant NAS Care (SUPPORT)
Status: RECRUITING
Conditions: Opioid Use Disorder|Neonatal Abstinence Syndrome
Interventions: BEHAVIORAL: An implementation model for co-located Medications for Opioid Use Disorder (MOUD) prescription in the NICU
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Comparison of the Macintosh, King Vision®, Glidescope® and AirTraq® Laryngoscopes in Routine Airway Management
Status: COMPLETED
Conditions: Patients Need Tracheal Intubation
Interventions: DEVICE: Macintosh|DEVICE: King Vision|DEVICE: Glidescope|DEVICE: AirTraq
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study to Evaluate the Analgesic Efficacy of 28 Days' Oral Administration of AZD2066 Compared With Placebo in Patients With Painful Diabetic Neuropathy
Status: COMPLETED
Conditions: Pain|Diabetic Neuropathy
Interventions: DRUG: AZD2066|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Determine the Safety and Efficacy of Once Daily Raltegravir Compared to Twice Daily Raltegravir (MK-0518-071)
Status: TERMINATED
Conditions: HIV
Interventions: DRUG: Comparator: Raltegravir 400 mg b.i.d.|DRUG: Experimental: Raltegravir 800 mg q.d.|DRUG: TRUVADA™
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of CWP232291 in Relapsed or Refractory Myeloma Patients
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Phase 1a: CWP232291|DRUG: Phase 1b: CWP232291, Lenalidomide, Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Bumetanide to Improve Cognitive Functions in Down Syndrome
Status: RECRUITING
Conditions: Down Syndrome
Interventions: DRUG: Bumetanide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Robotic Exoskeletons Therapy for Gait Rehabilitation in Patients With Incomplete Spinal Cord Injury.
Status: COMPLETED
Conditions: Spinal Cord Injury|Incomplete Spinal Cord Injury
Interventions: DEVICE: Walking therapy with Exo-H2 exoskeleton
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Investigate CSL112 in Subjects With Acute Coronary Syndrome
Status: COMPLETED
Conditions: Acute Coronary Syndrome
Interventions: BIOLOGICAL: Apolipoprotein A-I [human] (apoA-I)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: CAR T Cells in Patients With MMP2+ Recurrent or Progressive Glioblastoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Glioblastoma Multiforme of Brain
Interventions: BIOLOGICAL: CHM-1101 CAR-T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Niraparib Added to Anti-PD-L1 Antibody Maintenance in SLFN11-positive, Extensive-disease SCLC
Status: RECRUITING
Conditions: SCLC,Extensive Stage|SLFN11-positive
Interventions: DRUG: Niraparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Community Pharmacist Managed Asthma Consultation Service
Status: COMPLETED
Conditions: Uncontrolled Asthma
Interventions: OTHER: Pharmacist led Asthma Management|OTHER: Pharmacist Intervention (when requested by patient)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Developing Inclusive Youth: Promoting Intergroup Friendships and Inclusive Classrooms in Childhood
Status: COMPLETED
Conditions: Social Exclusion|Prejudice, Racial|Prejudice|Sexism|Peer Group
Interventions: BEHAVIORAL: Developing Inclusive Youth (DIY)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Safety Study of Octreotide Implant in Patients With Acromegaly
Status: TERMINATED
Conditions: Acromegaly
Interventions: DRUG: Octreotide Implant|DRUG: Sandostatin LAR Depot
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial Using Bipolar Technology for Transurethral Resection of Bladder Tumor
Status: UNKNOWN
Conditions: Urinary Bladder Tumor
Interventions: DEVICE: Monopolar diathermy|DEVICE: Bipolar diathermy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tanespimycin and Cytarabine in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Chronic Myelogenous Leukemia, Chronic Myelomonocytic Leukemia, or Myelodysplastic Syndromes
Status: COMPLETED
Conditions: Accelerated Phase Chronic Myelogenous Leukemia|Adult Acute Basophilic Leukemia|Adult Acute Eosinophilic Leukemia|Adult Acute Megakaryoblastic Leukemia (M7)|Adult Acute Minimally Differentiated Myeloid Leukemia (M0)|Adult Acute Monoblastic Leukemia (M5a)|Adult Acute Monocytic Leukemia (M5b)|Adult Acute Myeloblastic Leukemia With Maturation (M2)|Adult Acute Myeloblastic Leukemia Without Maturation (M1)|Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities|Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)|Adult Acute Myeloid Leukemia With t(16;16)(p13;q22)|Adult Acute Myeloid Leukemia With t(8;21)(q22;q22)|Adult Acute Myelomonocytic Leukemia (M4)|Adult Erythroleukemia (M6a)|Adult Pure Erythroid Leukemia (M6b)|Blastic Phase Chronic Myelogenous Leukemia|Chronic Myelomonocytic Leukemia|de Novo Myelodysplastic Syndromes|Previously Treated Myelodysplastic Syndromes|Recurrent Adult Acute Lymphoblastic Leukemia|Recurrent Adult Acute Myeloid Leukemia|Refractory Anemia With Excess Blasts in Transformation|Relapsing Chronic Myelogenous Leukemia|Secondary Acute Myeloid Leukemia|Secondary Myelodysplastic Syndromes
Interventions: DRUG: tanespimycin|DRUG: cytarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Novel Application of Indocyanine Green as a Biomarker to Identify Tissue Necrosis in Mastectomy Patients
Status: COMPLETED
Conditions: Breast Cancer|Necrosis
Interventions: DIAGNOSTIC_TEST: ICG microangiography
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Whole Body Vibration on Insulin Resistance in Females With Polycystic Ovarian Syndrome
Status: COMPLETED
Conditions: Polycystic Ovarian Syndrome|Insulin Resistance
Interventions: DEVICE: whole body vibration|DEVICE: Treadmill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Testing the Contribution of Orbitofrontal Cortex Networks to Decision-making
Status: RECRUITING
Conditions: Healthy
Interventions: DEVICE: Real transcranial magnetic stimulation (TMS) before conditioning|DEVICE: Real transcranial magnetic stimulation (TMS) before devaluation test|DEVICE: Sham transcranial magnetic stimulation (TMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Tolerability of Rimegepant for the Prevention of Migraine in Adults With History of Inadequate Response to Oral Preventive Medications
Status: RECRUITING
Conditions: Migraine
Interventions: DRUG: Rimegepant|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Benefits of a Household WASH Package to Community-based Management of Acute Malnutrition (CMAM) Program, Chad
Status: COMPLETED
Conditions: Severe Malnutrition
Interventions: BEHAVIORAL: Hygiene promotion sessions|DEVICE: Household WASH package|BEHAVIORAL: Household visit|BEHAVIORAL: Group discussions after successful discharge|PROCEDURE: Outpatient Therapeutic Programme
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mobile Behavioral Ecological Momentary Assessment and Intervention in Rakai, Uganda
Status: COMPLETED
Conditions: Ecological Momentary Assessment and Intervention
Interventions: BEHAVIORAL: Ecological momentary assessment and intervention: Behaviorally-dependent messaging|BEHAVIORAL: Ecological momentary assessment only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Early Detection of Atherosclerosis: a Randomized Trial in the Primary Prevention of Cardiovascular Diseases.
Status: UNKNOWN
Conditions: Atherosclerosis|Cardiovascular Diseases
Interventions: DRUG: Simvastatin or Atorvastatin|DRUG: Enalapril|DRUG: Aspirin or clopidogrel|DRUG: Rimonabant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Monitoring of Chimerism After Transplantation in Patients With β Thalassemia Major and the Treatment Strategies for the Reduction of Chimerism
Status: UNKNOWN
Conditions: Beta Thalassemia Major
Interventions: DRUG: Interleukin-2|DRUG: Donor Regulatory T-Lymphocytes
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Safety of Liraglutide as Adjunct Therapy to Insulin in the Treatment of Type 1 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 1
Interventions: DRUG: liraglutide|DRUG: placebo|DRUG: liraglutide|DRUG: placebo|DRUG: liraglutide|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Autologous Bone Marrow Derived Mesenchymal Stromal Cells (BM-MSCs) in Patients With Chronic Kidney Disease (CKD)
Status: COMPLETED
Conditions: Chronic Kidney Disease
Interventions: BIOLOGICAL: Intravenous injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Imaging and Genomic Biomarkers to Predict Response in Prostate Cancer
Status: RECRUITING
Conditions: Prostate Cancer
Interventions: RADIATION: External beam radiation therapy|RADIATION: Prostate brachytherapy boost|DRUG: Androgen deprivation therapy|DIAGNOSTIC_TEST: Positron emission tomography (PET)/magnetic resonance imaging (MRI)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Olaparib as Adjuvant Treatment in Patients With Germline BRCA Mutated High Risk HER2 Negative Primary Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Olaparib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect Of Educational Intervention Based On Supportive Leadership
Status: COMPLETED
Conditions: The Effects of Educational Intervention on Nurses Performance
Interventions: OTHER: Assessing the Effect Of Educational Intervention Based On Supportive Leadership Behavior on Iranian head nurses leadership performance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Effect of Nerve Blockades in Addition to General Anesthesia in Surgical Fixation of Ankle Fractures.
Status: WITHDRAWN
Conditions: Ankle Fracture in Need of Surgical Fixation
Interventions: DRUG: Ropivacaine block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Gut Microbiota and Glioblastoma Multiforme Prognosis
Status: UNKNOWN
Conditions: Gut Microbiota, Glioblastoma Multiforme, Microglia, Tumor Related Macrophagocyte, Prognosis
Interventions: OTHER: Chemotherapy with temozolomide or no chemotherapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: "Holding-cuddling" Plus Oral Sucrose Versus Oral Sucrose for Reducing Venipuncture Pain in Newborns and Infants
Status: COMPLETED
Conditions: Blood Sampling
Interventions: PROCEDURE: Holding-cuddling|PROCEDURE: Sucrose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Novel Use of Probenecid to Alleviate Symptoms of Opioid Withdrawal
Status: RECRUITING
Conditions: Chronic Pain|Drug Dependence of Morphine Type|Symptom, Withdrawal
Interventions: DRUG: Probenecid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Relative Bioavailability Study of Gabapentin Tablets 800 mg Under Fasting Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Gabapentin 800 mg Tablets, single dose|DRUG: NEURONTIN® 800 mg Tablets, single dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: PK Bioequivalence Single-dose Safety Tolerability Study in Healthy Male Volunteers to Compare CBT124 & Avastin(EU&US)
Status: UNKNOWN
Conditions: Healthy
Interventions: BIOLOGICAL: CBT124|BIOLOGICAL: EU Sourced Avastin®|BIOLOGICAL: US Sourced Avastin®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Safety and Immunogenicity Study of AIDS Vaccine (Combined Use of DNA Vaccine and Recombinant Vaccinia Virus Tiantan)
Status: COMPLETED
Conditions: AIDS
Interventions: BIOLOGICAL: DNA vaccine|BIOLOGICAL: DNA vaccine prime with the addition of electroporation|BIOLOGICAL: rTV boost|BIOLOGICAL: rTV boost|BIOLOGICAL: rTV boost
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Self Abrading Rapidly Applied Electrode Validation
Status: COMPLETED
Conditions: ELECTROENCEPHALOGRAPHIC VARIANT PATTERN 1 (Disorder)
Interventions: DEVICE: SARA electrode|DEVICE: Gold cup
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Endoscopic Evaluation of Lower Gastrointestinal Bleeding (GIB) in Patients Presenting With Melena
Status: COMPLETED
Conditions: Gastrointestinal Hemorrhage
Interventions: PROCEDURE: Capsule endoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Curcumin in Pediatric Ulcerative Colitis
Status: WITHDRAWN
Conditions: Ulcerative Colitis
Interventions: DIETARY_SUPPLEMENT: Curcumin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of National Cancer Institute (NCI) Smoking Intervention Resources
Status: COMPLETED
Conditions: Smoking Cessation|Smoking|Nicotine Dependence
Interventions: OTHER: CIS - telephone cessation quitline counseling|OTHER: Lozenge - nicotine mini-lozenges|OTHER: Emails - Brief smoking prevention messages|OTHER: Full website - standard smokefree.gov website content|OTHER: Lite website - lite version of smokefree.gov|OTHER: Full mailed booklet - NCI's detailed 36-page quit guide|OTHER: brief mailed booklet - smaller version of NCI's booklet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Use of One Kind of Controllable Tube Ileostomy in the Low Rectal Cancer
Status: COMPLETED
Conditions: Rectal Neoplasms|Low Anterior Resection
Interventions: DEVICE: Low anterior resection|DEVICE: tube ileostomy|DEVICE: loop ileostomy|DEVICE: accept reversal operation|DEVICE: remove the tube ileostomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Ovamax on Oocyte Quality
Status: RECRUITING
Conditions: Female|Infertility
Interventions: OTHER: Ova-max|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CAP-100 for Subjects With Relapsed/Refractory Chronic Lymphocytic Leukemia
Status: RECRUITING
Conditions: Lymphocytic Leukemia, Chronic|SLL
Interventions: DRUG: CAP-100
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combining Intratumoral Flu Vaccine and Systemic Pembrolizumab in Patients With Early pMMR Colorectal Cancer
Status: NOT_YET_RECRUITING
Conditions: Colorectal Cancer
Interventions: DRUG: Influenza vaccine|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Virological and Immunological Determinants of Arbovirus Infection in New Caledonia
Status: RECRUITING
Conditions: Arbovirus Infections|Zika|Dengue|Chikungunya
Interventions: OTHER: Blood sample collection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study To Evaluate The Efficacy, Safety, Pharmacokinetics, And Pharmacodynamics Of Satralizumab In Participants With Thyroid Eye Disease
Status: RECRUITING
Conditions: Thyroid Eye Disease|TED
Interventions: DRUG: Satralizumab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Optimizing Viral Load Suppression in Kenyan Children on Antiretroviral Therapy
Status: COMPLETED
Conditions: Chronic HIV Infection
Interventions: DIAGNOSTIC_TEST: POC VL and targeted DRM testing.|DIAGNOSTIC_TEST: SOC VL testing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Docetaxel and Irinotecan in Treating Patients With Advanced Solid Tumors
Status: COMPLETED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: docetaxel|DRUG: irinotecan hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Dry Needling for Cervicogenic Headache
Status: COMPLETED
Conditions: Headache|Cervicogenic Headache
Interventions: PROCEDURE: Dry Needling|OTHER: Upper extremity stretching program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Study Testing CP-675,206 In Combination With Gemcitabine In Patients With Previously Untreated, Advanced Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DRUG: CP-675,206 and gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study Evaluating Wound Closure With Endoform™ and Symphony™
Status: RECRUITING
Conditions: Wound Healing|Diabetic Foot|Chronic Foot Ulcer|Foot Ulcer
Interventions: DEVICE: Endoform™ Antibacterial|DEVICE: Endoform™ Natural|DEVICE: Symphony™
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Therapy Treatment Response Trial in Patients With Leptomeningeal Metastases ((LM) Using CNSide
Status: TERMINATED
Conditions: Leptomeningeal Metastasis|Leptomeningeal Disease|Leptomeningeal Neoplasms|Breast Cancer|Non-Small Cell Lung Cancer
Interventions: DEVICE: CNSide
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Honolulu Heart Program
Status: COMPLETED
Conditions: Cardiovascular Diseases|Coronary Disease|Cerebrovascular Accident|Heart Diseases|Heart Failure, Congestive|Myocardial Infarction|Asthma|Emphysema|Lung Diseases, Obstructive|Aortic Aneurysm, Abdominal|Bronchitis|Dementia|Hypertension|Chronic Obstructive Pulmonary Disease|Heart Failure
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Spironolactone and Vitamin E in Patients With Nonalcoholic Fatty Liver Disease
Status: COMPLETED
Conditions: Fatty Liver|Steatohepatitis
Interventions: DRUG: Spironolactone/Vitamin E
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nivolumab Plus Relatlimab in Patients With Metastatic Uveal Melanoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Uveal Melanoma
Interventions: DRUG: Nivolumab|DRUG: Relatlimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 180 Degree vs. 360 Degree Selective Laser Trabeculoplasty as Initial Therapy for Glaucoma
Status: COMPLETED
Conditions: Open Angle Glaucoma|Ocular Hypertension|Glaucoma, Open Angle, Pseudo-exfoliative|Pigment Dispersion Syndrome|Glaucoma
Interventions: PROCEDURE: Selective Laser Trabeculoplasty|DEVICE: Neodymium:Yttrium Aluminum Garnet (YAG) laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cardiopulmonary Rehabilitation In Heart Valve Surgery
Status: RECRUITING
Conditions: Heart Valve Diseases
Interventions: OTHER: Conventional Cardiopulmonary Rehabilitation|OTHER: Bottle P.E.P. (Pozitive Expiratory Pressure)|OTHER: Early Mobilization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Open Label Study of Alacramyn® in Pediatric Patients With Scorpion Sting Envenomation
Status: COMPLETED
Conditions: Scorpion Sting Envenomation
Interventions: BIOLOGICAL: Antivenin Centruroides (scorpion) equine immune F(ab')2
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility Study on the Use of Redormin®500 on Day-time Cognition
Status: COMPLETED
Conditions: Sleep Disorders, Circadian Rhythm|Cognitive Dysfunction
Interventions: DRUG: Valerian-Hop Extract|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Bevacizumab Plus Modiifed FOLFIRINOX in Ovarian, Fallopian Tube, or Primary Peritoneal Mucinous Carcinoma
Status: RECRUITING
Conditions: Mucinous Ovarian Cancer|Fallopian Tube Cancer|Primary Peritoneal Cancer
Interventions: DRUG: Bevacizumab + modified FOLFIRINOX
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Validity and Reliability of the Modified Four Square Step Test (mFSST)
Status: COMPLETED
Conditions: Cerebral Palsy|Diplegic Cerebral Palsy|Hemiplegic Cerebral Palsy|Gait Disorders, Neurologic|Gait, Spastic|Gait Disorders in Children
Interventions: OTHER: repeated assessments
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phase III Trial Comparing Methotrexate and Cetuximab in First-line Treatment of Recurrent and/or Metastatic Squamous Cell Head and Neck Cancer
Status: COMPLETED
Conditions: Head Neck Cancer Squamous Cell Recurrent
Interventions: DRUG: Cetuximab|DRUG: Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety, Tolerability and Efficacy Study of ACE-011 in Patients With Osteolytic Lesions of Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: BIOLOGICAL: ACE-011|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dose Finding for the Treatment of Rhinitis/Rhinoconjunctivitis Against Grass Pollen Allergy
Status: COMPLETED
Conditions: Rhinitis|Rhinoconjunctivitis
Interventions: BIOLOGICAL: MG56 Mannosylated 500 subcutaneous|BIOLOGICAL: MG56 Mannosylated 1000 subcutaneous|BIOLOGICAL: MG56 Mannosylated 3000 subcutaneous|BIOLOGICAL: MG56 Mannosylated 5000 subcutaneous|BIOLOGICAL: MG56 Mannosylated 500 sublingual|BIOLOGICAL: MG56 Mannosylated 1000 sublingual|BIOLOGICAL: MG56 Mannosylated 3000 sublingual|BIOLOGICAL: MG56 Mannosylated 5000 sublingual|BIOLOGICAL: Subcutaneous placebo|BIOLOGICAL: Sublingual placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SCREENING
Clinical trial: Evaluation of Clinical Performance of Class IV Restoration Using Organically Modified Ceramic (OMNOCER) in Comparison to a Methacrylate Based Composite Resin
Status: COMPLETED
Conditions: Shade Match
Interventions: OTHER: (Admira Fusion, Voco GmbH, Germany)|OTHER: Methacrylate Based Composite
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Paliperidone Palmitate 3 Month and 1 Month Formulations for the Treatment of Patients With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: PP3M 175 mg eq.|DRUG: PP3M 263 mg eq.|DRUG: PP3M 350 mg eq.|DRUG: PP3M 525 mg eq.|DRUG: Placebo (20% Intralipid)|DRUG: PP1M 50 mg eq.|DRUG: PP1M 75 mg eq.|DRUG: PP1M 100 mg eq.|DRUG: PP1M 150 mg eq.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Single-dose Incremental Intravenous Injection of SY-007 in Healthy Subjects
Status: COMPLETED
Conditions: Cerebral Apoplexy
Interventions: DRUG: SY-007
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fluoride Therapies on Hypersensitive Carious Lesions in Primary Teeth
Status: COMPLETED
Conditions: Dentin Hypersensitivity|Active Dental Caries
Interventions: DRUG: 38% Silver Fluoride and Potassium Iodide solution (generic name; Riva Star®)|DRUG: Sodium fluoride varnish (generic name; Duraphat®)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ABG Oxidative Stress Study Protocol-1
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Plant concentrate A|DIETARY_SUPPLEMENT: Plant concentrate B|DIETARY_SUPPLEMENT: Plant concentrate C|DIETARY_SUPPLEMENT: Plant concentrate D
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Effective Treatment of Oral Helicobacter Pylori With the Success Rate of Gastric Eradication
Status: COMPLETED
Conditions: Oral Helicobacter Pylori
Interventions: DRUG: Amoxicillin and Tetracyclines|DRUG: Mouth washing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Effects of Paraffin Bath Therapy and ESWT on Quality of Life and Sleep in De Quervain Tenosynovitis
Status: COMPLETED
Conditions: De Quervain Disease
Interventions: DEVICE: Paraffin Bath Therapy|DEVICE: Extracorporeal Shock Wave Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Onnit Labs New Mood Supplementation in Healthy College Students
Status: COMPLETED
Conditions: Mental Health Wellness 1
Interventions: DIETARY_SUPPLEMENT: Multi-Ingredient Herbal Supplement|DIETARY_SUPPLEMENT: Placebo Supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of a Paleolithic Lifestyle Intervention in Breast Cancer Patients Undergoing Radiotherapy
Status: COMPLETED
Conditions: Breast Cancer|Body Weight Changes
Interventions: RADIATION: Curative radiotherapy|OTHER: Paleolithic lifestyle intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Combining Bortezomib With High Dose Melphalan to Treat Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Bortezomib 1 mg/m2|DRUG: Bortezomib 1.3 mg/m2|DRUG: Bortezomib 1.6 mg/m2|DRUG: Melphalan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stopping Postpartum Vitamin A Supplementation: Missing Concealed Benefit
Status: COMPLETED
Conditions: Vitamin A Deficiency
Interventions: DIETARY_SUPPLEMENT: Vitamin A (<3-day postpartum)|DIETARY_SUPPLEMENT: Vitamin A (6 wk postpartum)|DIETARY_SUPPLEMENT: Vitamin A (<3-day and 6 wk postpartum)|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: HER-2 Pulsed DC Vaccine to Prevent Recurrence of Invasive Breast Cancer Post Neoadjuvant Chemotherapy
Status: COMPLETED
Conditions: Breast Cancer
Interventions: BIOLOGICAL: HER-2 pulsed Dendritic Cell Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Comparison of Gentle Human Touch's Effect by Mother and Nurse on Pain Level During Heel Blood Sampling in Preterm Infants
Status: NOT_YET_RECRUITING
Conditions: Infant, Premature
Interventions: OTHER: Gentle Human Touch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of Treatment With Pridopidine (ACR16) in Participants With Huntington's Disease
Status: COMPLETED
Conditions: Huntington's Disease
Interventions: DRUG: ACR16|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effect of Low Level Laser Light on Low Back Pain
Status: COMPLETED
Conditions: Low Back Pain
Interventions: DEVICE: Erchonia FX-635|DEVICE: Placebo Laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of the Variation in the Time of Systemic Administration of Metronidazole and Amoxicillin Associated to the Non-surgical Therapy of Chronic Periodontitis.
Status: COMPLETED
Conditions: Chronic Periodontitis|Clinical and Microbiological Effects
Interventions: DRUG: Administration of Metronidazole plus Amoxicillin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT