pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Acute Labetalol Use in Preeclampsia
Status: TERMINATED
Conditions: Preeclampsia With Severe Features
Interventions: DRUG: Experimental labetalol dose|OTHER: Current standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assess the Drug Interactions of BBT-877 and Midazolam, Itraconazole, and Esomeprazole in Healthy Adult Subjects
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DRUG: BBT-877|DRUG: Midazolam|DRUG: Itraconazole|DRUG: Esomeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety Trial of Nivolumab in Patients With Advanced or Metastatic Non-Small Cell Lung Cancer Who Have Progressed During or After Receiving At Least One Prior Chemotherapy Regimen
Status: COMPLETED
Conditions: Non Small Cell Lung Cancer (NSCLC)
Interventions: DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral Risperidone Versus Injectable Paliperidone Palmitate for Treating First-Episode Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia (Recent-onset)
Interventions: DRUG: paliperidone palmitate|DRUG: risperidone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Regulatory Post-marketing Surveillance (rPMS) Study to Evaluate the Safety and Effectiveness of Saxenda®(Liraglutide 3.0 mg) in Obese Patients and Overweight Patients With Obesity-related Comorbidities in Routine Clinical Practice in Korea.
Status: COMPLETED
Conditions: Obesity|Overweight
Interventions: DRUG: Liraglutide
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Patient Reported Outcomes With UVA-1 Therapy for Treatment of Sclerosing Skin Diseases
Status: ENROLLING_BY_INVITATION
Conditions: Scleroderma, Systemic|Morphea|Graft Vs Host Disease
Interventions: DEVICE: UVA-1 Phototherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transhiatal Tunnel Valvuloplasty for Reconstruction Following the Laparoscopic Proximal Gastrectomy
Status: RECRUITING
Conditions: Gastric Cancer
Interventions: PROCEDURE: the Transhiatal Tunnel Valvuloplasty technique
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rapamycin+Estradiol- vs. Rapamycin-Eluting Stents to Reduce Restenosis (ISAR-PEACE)
Status: COMPLETED
Conditions: Coronary Heart Disease
Interventions: DEVICE: rapamycin plus 17beta estradiolvalerat-eluting stent|DEVICE: rapamycin-eluting stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Individualized Music Playlist Based on ISO Principle for De-escalation of Agitation in Dementia
Status: NOT_YET_RECRUITING
Conditions: Dementia
Interventions: BEHAVIORAL: Individualized music playlist|BEHAVIORAL: Preferred music|BEHAVIORAL: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: CpG-STAT3 siRNA CAS3/SS3 and Localized Radiation Therapy for the Treatment of Relapsed/Refractory B-Cell NHL
Status: WITHDRAWN
Conditions: Recurrent B-Cell Non-Hodgkin Lymphoma|Recurrent Diffuse Large B-Cell Lymphoma|Recurrent Grade 1 Follicular Lymphoma|Recurrent Grade 2 Follicular Lymphoma|Recurrent Grade 3 Follicular Lymphoma|Recurrent Grade 3a Follicular Lymphoma|Recurrent Grade 3b Follicular Lymphoma|Recurrent Mantle Cell Lymphoma|Recurrent Marginal Zone Lymphoma|Recurrent Small Lymphocytic Lymphoma|Refractory B-Cell Non-Hodgkin Lymphoma|Refractory Diffuse Large B-Cell Lymphoma|Refractory Grade 1 Follicular Lymphoma|Refractory Grade 2 Follicular Lymphoma|Refractory Grade 3 Follicular Lymphoma|Refractory Grade 3a Follicular Lymphoma|Refractory Mantle Cell Lymphoma|Refractory Marginal Zone Lymphoma|Refractory Small Lymphocytic Lymphoma|Refractory Grade 3b Follicular Lymphoma
Interventions: BIOLOGICAL: CpG-STAT3 siRNA CAS3/SS3|RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 2, Observer-Blind, Placebo-Controlled, Randomized, Multi-Center Extension Study to Evaluate the Safety and Immunogenicity of a Booster Dose of a MenABCWY Vaccine Administered 24 Months Following the Primary Series to Adolescents and Young Adults Who Participated in V102_03 (NCT01272180)
Status: COMPLETED
Conditions: Meningococcal Disease
Interventions: BIOLOGICAL: MenABCWY+OMV|BIOLOGICAL: MenABCWY+¼OMV|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of Immunogenicity of Inactivated Poliovirus Vaccine (IPV) Administered Intramuscularly or Intradermally
Status: COMPLETED
Conditions: Polio
Interventions: BIOLOGICAL: Inactivated poliovirus vaccine in reduced doses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Using a PET Imaging Agent, 18F-Clofarabine (CFA), to Measure Deoxycytidine Kinase Activity in Metastatic Cancer
Status: RECRUITING
Conditions: Metastatic Cancer|Carcinoma|Adenocarcinoma
Interventions: DRUG: 18F-Clofarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Valsartan Compared to Enalapril on Sitting Systolic Blood Pressure in Children With High Blood Pressure
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Valsartan|DRUG: Enalapril
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Neuroprotection With Statin Therapy for Acute Recovery Trial Phase 2
Status: COMPLETED
Conditions: Stroke|Rhabdomyolysis|Jaundice
Interventions: DRUG: Low Dose Lovastatin|OTHER: Placebo|DRUG: High Dose Lovastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study to Evaluate the Efficacy and Safety of F520 Combined With F007 in Patients With RR DLBCL
Status: UNKNOWN
Conditions: RR DLBCL; PD-1; CD20
Interventions: DRUG: F520+F007
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Lovaza® in Acute Myocardial Infarction
Status: TERMINATED
Conditions: Myocardial Infarction
Interventions: DRUG: Lovaza®|DRUG: The placebo contained 1 gram of corn oil in each capsule.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The MObile AssessMENT of Behavioral and Psychological Symptoms of Dementia in Amnestic MCI and AD (MOMENT) Study
Status: TERMINATED
Conditions: Alzheimer Disease|Mild Memory Disturbance|Mild Cognitive Impairment
Interventions: OTHER: Mobile Phone Application Assessments|OTHER: Standard Assessments
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Randomized,Double-blind, Placebo Controlled, Multicenter Study to Evaluate the Safety and Efficacy of MT2004 Capsule in DILI Subjects
Status: RECRUITING
Conditions: Drug-Induced Liver Injury|Cholestatic Liver Injury|Mixed Liver Injury
Interventions: DRUG: MT2004 Capsule|DRUG: MT2004 Capsule Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Vedolizumab IV in Chinese Participants With Ulcerative Colitis
Status: RECRUITING
Conditions: Moderately to Severely Active Ulcerative Colitis
Interventions: DRUG: Vedolizumab IV|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety of Aerius Syrup in Pediatric Patients Aged 1-5 Years Old With Allergic Rhinitis or Chronic Idiopathic Urticaria (Study P04446AM1)(COMPLETED)
Status: COMPLETED
Conditions: Rhinitis|Urticaria
Interventions: DRUG: Desloratadine
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Relative Bioavailability of Three Oral Formulations Candidates of Rilpivirine for Potential Pediatric Use Compared to Oral Tablet
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Rilpivirine Oral Tablet|DRUG: Rilpivirine formulation G007|DRUG: Rilpivirine formulation G009-01|DRUG: Rilpivirine formulation G002|DIETARY_SUPPLEMENT: Standardized Breakfast
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Conservative Treatments of Retinoblastoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Retinoblastoma|Children|Retinal Neoplasm
Interventions: DRUG: VP16, carboplatin|DRUG: Melphalan|DRUG: VP16, carboplatin, vincristin|DRUG: Carboplatin + laser day 1 (chemothermotherapy)|DEVICE: Laser (local treatment)|DEVICE: cryoapplication (local treatment)|RADIATION: I125 radioactive plaques (local treatment)|DRUG: intravitreal Melphalan (local treatment)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Pharmacodynamic Trial to Determine the Effects of Bardoxolone Methyl on eGFR in Patients With Type 2 Diabetes and Chronic Kidney Disease
Status: COMPLETED
Conditions: Renal Insufficiency, Chronic|Diabetes Mellitus, Type 2
Interventions: DRUG: Bardoxolone methyl (amorphous dispersion)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adding Modified Visual Feedback Training in Patients Following ACL Reconstruction
Status: RECRUITING
Conditions: Anterior Cruciate Ligament Reconstruction
Interventions: OTHER: Physical therapy traditional neuromuscular training, NMT|OTHER: Physical therapy modified visual feedback, MVF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Neural Basis of Music-based Neurological Rehabilitation for Traumatic Brain Injury
Status: COMPLETED
Conditions: Traumatic Brain Injury (TBI)
Interventions: BEHAVIORAL: Music-based Neurological Rehabilitation (MBNR)|OTHER: Standard Care (SC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Crossover Study to Evaluate the Safety, Tolerability and Efficacy of XPF-002 in Subjects With Postherpetic Neuralgia (PHN)
Status: COMPLETED
Conditions: Postherpetic Neuralgia
Interventions: DRUG: XPF-002|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: First-in-Human Study of the SHP2 Inhibitor BBP-398 in Patients With Advanced Solid Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Tumor, Solid
Interventions: DRUG: BBP-398 (Formerly known as IACS-15509)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assess Efficacy and Safety of TachoComb H vs. Standard Surgical Treatment (i.e. Suturing) in Patients Undergoing Prostatectomy (TC-017-AU)
Status: COMPLETED
Conditions: Control of Local Bleeding in Patients Undergoing Prostatectomy.
Interventions: DRUG: Human fibrinogen/thrombin and bovine aprotinin (TachoComb H)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Survivorship Care Planning in Patients With Colorectal or Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Stage I Colon Cancer|Stage I Rectal Cancer|Stage IA Non-small Cell Lung Cancer|Stage IB Non-small Cell Lung Cancer|Stage IIA Colon Cancer|Stage IIA Non-small Cell Lung Cancer|Stage IIA Rectal Cancer|Stage IIB Colon Cancer|Stage IIB Non-small Cell Lung Cancer|Stage IIB Rectal Cancer|Stage IIC Colon Cancer|Stage IIC Rectal Cancer|Stage IIIA Colon Cancer|Stage IIIA Non-small Cell Lung Cancer|Stage IIIA Rectal Cancer|Stage IIIB Colon Cancer|Stage IIIB Non-small Cell Lung Cancer|Stage IIIB Rectal Cancer|Stage IIIC Colon Cancer|Stage IIIC Rectal Cancer
Interventions: OTHER: educational intervention|OTHER: questionnaire administration|PROCEDURE: quality-of-life assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: GEM+Nab-Paclitaxel Plus Losartan Followed by Stereotactic Radiotherapy for Locally Advanced Pancreatic Cancer
Status: RECRUITING
Conditions: Pancreatic Cancer
Interventions: DRUG: Losartan|DRUG: Gemcitabine|DRUG: Nab paclitaxel|RADIATION: Stereotactic Body Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Craniosacral Therapy in Migraine: A Feasibility Study
Status: COMPLETED
Conditions: Migraine Headaches
Interventions: OTHER: Craniosacral therapy|PROCEDURE: Low strength static magnets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Vaginal Misoprostol and Dinoprostone Prior to Copper Intrauterine Device Insertion in Nulliparous Women
Status: COMPLETED
Conditions: IUD Insertion Complication
Interventions: DRUG: Dinoprostone|DRUG: Misoprostol|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tumor Cell and DNA Detection in the Blood, Urine and Bone Marrow of Patients With Solid Cancers
Status: RECRUITING
Conditions: Non-small Cell Lung Cancer|Esophageal Cancer|Gastric Cancer|Pancreatic Cancer|Hepatocellular Cancer|Colorectal Cancer
Interventions: PROCEDURE: Study sample collection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Blood Flow Restriction Training to Muscle Strength, Dynamic Stability, and ACL Injury Prevention
Status: RECRUITING
Conditions: Healthy Subjects|Sports Level 1
Interventions: PROCEDURE: Low-load Blood Flow Restriction training|PROCEDURE: Sham Low-load Blood Flow Restriction training|PROCEDURE: High-load Eccentric training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Bariatric Surgery vs. Lifestyle Modification for NASH
Status: UNKNOWN
Conditions: NASH - Nonalcoholic Steatohepatitis
Interventions: PROCEDURE: Bariatric Surgery|BEHAVIORAL: Lifestyle modification
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effect of Multiple Doses of Isavuconazole on the Pharmacokinetics of Methotrexate
Status: COMPLETED
Conditions: Pharmacokinetics of Isavuconazole|Pharmacokinetics of Methotrexate|Pharmacokinetics of 7-hydroxymethotrexate|Healthy Subjects
Interventions: DRUG: isavuconazole|DRUG: methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: BEZ235 Phase II Trial in Patients With Advanced Pancreatic Neuroendocrine Tumors (pNET) After Failure of mTOR Inhibitor Therapy.
Status: COMPLETED
Conditions: Pancreatic Neuroendocrine Tumors (pNET)
Interventions: DRUG: BEZ235 (Stage 1)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Evaluate Papilocare® Gel Efficacy Into Repairment of Cervical Lesions Caused by HPV
Status: COMPLETED
Conditions: HPV Infection|Lesion Cervix
Interventions: DEVICE: PAPILOCARE|DEVICE: PLACEBO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Validity and Reliability of Diagnostic Findings of SI Joint Blocking
Status: TERMINATED
Conditions: SI Joint Pain
Interventions: DRUG: 0.75% bupivacaine|DRUG: .75% bupivacaine|DRUG: .75% bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety and Efficacy Study of Pazopanib and MK 3475 in Advanced Renal Cell Carcinoma (RCC; KEYNOTE-018)
Status: COMPLETED
Conditions: Carcinoma, Renal Cell
Interventions: DRUG: Pazopanib|DRUG: MK-3475
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: New Prognostic and Predictive Biomarkers for HPV-associated Oropharyngeal Cancer
Status: RECRUITING
Conditions: PREDICTIVE BIOMARKERS|Evaluation of HPV-specific E5 Transcript Expression in a Cohort of Patients With HPV-associated OPC|HPV 16 Positive Oropharyngeal Tumors (OPC)
Interventions: DIAGNOSTIC_TEST: HPV-ASSOCIATED OROPHARYNGEAL CANCER
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: What SSI Duration is Most Effective? An Online Experiment With American Adults
Status: ACTIVE_NOT_RECRUITING
Conditions: Depression
Interventions: BEHAVIORAL: Action Brings Change Project (15-minute adult version)|BEHAVIORAL: Action Brings Change Project (10-minute adult version)|BEHAVIORAL: Action Brings Change Project (6-minute adult version)|BEHAVIORAL: Action Brings Change Project (2-minute adult version)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Vitamin D and Glucose Metabolism in Pediatrics
Status: UNKNOWN
Conditions: Insulin Resistance|Obesity|Vitamin D25 Insufficiency
Interventions: DRUG: Vitamin D drops|DRUG: Placebo drops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Open-label Extension to the Phase 2 Crossover Study (PRESIDIO) Evaluating KZR-616 in Patients With PM and DM.
Status: COMPLETED
Conditions: Polymyositis|Dermatomyositis
Interventions: DRUG: KZR-616
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 3BNC117 and 10-1074 in HIV Uninfected Adults
Status: COMPLETED
Conditions: Human Immunodeficiency Virus
Interventions: DRUG: 3BNC117|DRUG: 10-1074|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy of Recombinant Grass Pollen Allergen Cocktail in the Treatment of Allergic Rhinoconjunctivitis
Status: COMPLETED
Conditions: Allergy
Interventions: BIOLOGICAL: Recombinant grass pollen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Neuroscience Pain Education in Patients With Chronic Low Back Pain
Status: COMPLETED
Conditions: Chronic Low Back Pain|Manual Therapy|Neuroscience Pain Education
Interventions: OTHER: neuroscience pain education|OTHER: manual therapy|OTHER: home exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Automatic Diagnosis of Early Esophageal Squamous Neoplasia Using pCLE With AI
Status: UNKNOWN
Conditions: Esophageal Neoplasms|Artificial Intelligence|Confocal Laser Endomicroscopy
Interventions: DIAGNOSTIC_TEST: The diagnosis of Artificial Intelligence and endoscopist
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Use of Tranexamic Acid to Reduce Perioperative Blood Loss During High Risk Spine Fusion Surgery
Status: COMPLETED
Conditions: Curvature of Spine
Interventions: DRUG: Tranexamic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study on Mindfulness for Tobacco and Alcohol in University Students
Status: COMPLETED
Conditions: Nicotine Dependence|Alcohol Use
Interventions: BEHAVIORAL: Mindfulness Training for Smokers|BEHAVIORAL: Interactive Learning for Smokers
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Dietary Intake of Dried Whole Food Concentrates (Juice Plus) on Clinical Outcomes Following Periodontal Therapy: A Pilot Study
Status: COMPLETED
Conditions: Periodontitis
Interventions: DIETARY_SUPPLEMENT: Daily Juice Plus+ with vegetable & fruit & berry capsule|DIETARY_SUPPLEMENT: Daily Juice Plus+ vegetable & fruit & placebo capsule|DIETARY_SUPPLEMENT: Placebo in the form of 6 capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Inhaled Beta-adrenergic Agonists to Treat Pulmonary Vascular Disease in Heart Failure With Preserved EF (BEAT HFpEF): A Randomized Controlled Trial
Status: COMPLETED
Conditions: Congestive Heart Failure|Heart Failure, Left-Sided|Left-Sided Heart Failure
Interventions: DRUG: Albuterol|OTHER: Saline placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Tetanus and Diphtheria Toxoids Adsorbed Combined With Component Pertussis Vaccine and Inactivated Poliomyelitis
Status: COMPLETED
Conditions: Pertussis|Tetanus|Diphtheria|Poliomyelitis|Hepatitis B
Interventions: BIOLOGICAL: Tetanus and Diphtheria Toxoids Adsorbed Combined with Component Pertussis Vaccine and IPV|BIOLOGICAL: Hepatitis B vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Optimal Head and Neck Position During Videolaryngoscopy
Status: COMPLETED
Conditions: Head and Neck Position for Intubation
Interventions: OTHER: C-Mac D-Blade Videolaryngoscope|OTHER: C-Mac D-Blade Videolaryngoscope|OTHER: King Vision Videolaryngoscope|OTHER: King Vision Videolaryngoscope
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Escalating Single-dose Safety, Tolerability, and Pharmacokinetics of SQ109 in Healthy Volunteers
Status: COMPLETED
Conditions: Tuberculosis
Interventions: DRUG: SQ109
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ledipasvir/Sofosbuvir Fixed-Dose Combination for 12 or 24 Weeks in Genotype 1 or 4 HCV Infected Adults With Sickle Cell Disease
Status: COMPLETED
Conditions: Hepatitis C Virus Infection
Interventions: DRUG: LDV/SOF
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 3D Breast Ultrasound Elastography in Patients Under Neoadjuvant Chemotherapy
Status: COMPLETED
Conditions: Malignant Breast Tumours
Interventions: DEVICE: 3D Ultrasound elastography by means of shear wave propagation into breast tissue
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Lap TAP Block for Laparoscopic TEP Inguinal Hernia Repair: a Prospective, Double-blinded, Randomized, Clinical Trial
Status: UNKNOWN
Conditions: Laparoscopic TAP Block in TEP Inguinal Hernia Repair.
Interventions: DRUG: TAP Block Group|DRUG: Peri-Portal Block Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Inspiratory Muscle Training in Acute Decompensated Heart Failure
Status: NOT_YET_RECRUITING
Conditions: Acute Decompensated Heart Failure
Interventions: DEVICE: inspiratory muscle training device|OTHER: Physical training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: V-sitting Posture Stabilization Versus Modified Clamshell in Patients With Non-specific Chronic Low Back Pain.
Status: UNKNOWN
Conditions: Non-specific Chronic Low Back Pain
Interventions: OTHER: V-sitting posture stabilization|OTHER: Modified clamshell exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Trial of Iron Supplementation to Prevent Anemia in Very-low-birth-weight Infants
Status: COMPLETED
Conditions: Anemia
Interventions: DRUG: Iron Supplement|DRUG: control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 11C-acetate/18Fluorodeoxyglucose-FDG PET/CT and Cardiac MRI in Pulmonary Hypertension
Status: COMPLETED
Conditions: Pulmonary Hypertension
Interventions: DRUG: 11C-acetate|DRUG: [18F]Fluoro-2-deoxy-2-D-glucose|OTHER: Cardiac MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Testing an Evidence-Based Self-Help Program for Infertility-Related Distress in Women
Status: NOT_YET_RECRUITING
Conditions: Infertility|Distress, Emotional|Mental Health Issue
Interventions: BEHAVIORAL: Coping with Infertility Self-Help Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CytOSorb TreatMent Of Critically Ill PatientS Registry
Status: RECRUITING
Conditions: Septic Shock|Acute Respiratory Distress Syndrome|Trauma|Rhabdomyolysis|Cardiogenic Shock|Pancreatitis|Acute on Chronic Liver Failure|Acute Liver Failure|Burns|Chimeric Antigen Receptor T-Cell Therapy (CAR-T) Cytokine Release Syndrome (CRS)|Extracorporeal Life Support|Postoperative Endocarditis|Hemophagocytic Lymphohistiocytoses|Liver Transplant; Complications|Infectious Disease|Postoperative Vasoplegic Syndrome|Drug Overdose|Sepsis
Interventions: DEVICE: CytoSorb
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Combined tDCS+PNS After Acute Stroke
Status: UNKNOWN
Conditions: Acute Ischaemic Stroke
Interventions: DEVICE: combined transcranial direct current stimulation and electrical peripheral nerve stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: TAME-PD - Physical Therapy, Atomoxetine and, Methylphenidate, to Enhance Gait and Balance in Parkinson's Disease
Status: RECRUITING
Conditions: Parkinson's Disease, Idiopathic
Interventions: DRUG: Methylphenidate|OTHER: Physical Therapy|DRUG: Atomoxetine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ipratropium Bromide Spray as Treatment for Sialorrhea in Children
Status: UNKNOWN
Conditions: Sialorrhea
Interventions: DRUG: Ipratropium bromide|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Laser Etching Effect on Application Mode of Universal Adhesive
Status: ACTIVE_NOT_RECRUITING
Conditions: Healthy Participant
Interventions: PROCEDURE: Total-etch mode with 35% phosphoric acid (K-ETCHANT) (TE-A group)|PROCEDURE: Selective-etch mode with 35% phosphoric acid (K-ETCHANT) (SE-A group)|PROCEDURE: Total-etch mode with Er, Cr: YSGG laser (Waterlase MD) (TE-L group)|PROCEDURE: Selective-etch mode with Er, Cr: YSGG laser (Waterlase MD) (SE-L group).|PROCEDURE: Self-etch mode Clearfil Universal Bond Quick (Kuraray, Japan) (SE group)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Safety of SAB-176 to Prevent the Flu, Given IM in Healthy Adults Compared With Placebo
Status: RECRUITING
Conditions: PHA1A
Interventions: DRUG: Single Ascending Dose of SAB-176|DRUG: Single Ascending Dose of Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study Of AVANDAMET® With Or Without Insulin In Type II Diabetes Mellitus Patients. AVANDAMET® is a Registered Trademark of the GSK Group of Companies.
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Rosiglitazone/metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Epoetin Alfa Biosimilar in the Management of Chemotherapy-Induced Symptomatic Anemia in Haematology and Oncology
Status: COMPLETED
Conditions: Chemotherapy-induced Symptomatic Anemia|Solid Tumors|Malignant Hemopathies|Lymphomas|Myelomas
Interventions: DRUG: Epoetin biosimilar
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Safety and Efficiency of a Single Dose of CARC-101C in Patients With Autoimmune Type 1 Diabetes Mellitus
Status: NOT_YET_RECRUITING
Conditions: Autoimmune Type 1 Diabetes Mellitus(T1DM)
Interventions: DRUG: CARC-101C
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Does Botulinum A Toxin Help With Pain From Rotator Cuff Arthropathy?
Status: COMPLETED
Conditions: Rotator Cuff Tear Arthropathy
Interventions: DRUG: Botulinum Toxin Type A
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Statins on Oxidative Stress and Endothelial Progenitor Cells
Status: COMPLETED
Conditions: Diabetes Mellitus|Metabolic Syndrome X|Hypercholesterolemia
Interventions: DRUG: Atorvastatin|DRUG: Pravastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tranexamic Acid and Pediatric Adenotonsillectomy
Status: COMPLETED
Conditions: Tonsillectomy|Adenoidectomy|Tranexamic Acid
Interventions: DRUG: Tranexamic Acid|OTHER: normal saline solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Captisol Enabled Melphalan and Pharmacokinetics for Patients With Multiple Myeloma or Light Chain Amyloidosis That Are Receiving an Autologous Transplant.
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Myeloma|Amyloidosis
Interventions: DEVICE: Melphalan|DRUG: Pegfilgrastim|PROCEDURE: Autologous Hematopoietic Progenitor Cell Transplant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effect of Repeated Usage on the Tear Film Characteristics of an Investigational Eye Drop in Dry Eye Sufferers
Status: COMPLETED
Conditions: Dry Eye Syndrome
Interventions: DEVICE: Carboxymethylcellulose sodium, glycerin and polysorbate 80
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Novel Treatment Option for Neuropathic Pain
Status: COMPLETED
Conditions: Neuralgia|Complex Regional Pain Syndromes
Interventions: DRUG: Cetuximab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Metabolomic Impacts of Branched-chain Amino Acid Supplementation During Endurance Exercise
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Branched Chain Amino Acids|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Lenvatinib in Recurrent and/or Metastatic Adenoid Cystic Carcinomas of the Salivary Glands: ACC-LEN14
Status: COMPLETED
Conditions: Adenoid Cystic Carcinomas of the Salivary Glands
Interventions: DRUG: Lenvatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioavailability of Magnesium Supplements
Status: COMPLETED
Conditions: Healthy|Magnesium Deficiency
Interventions: DIETARY_SUPPLEMENT: Magnesium|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Surgical Management of Optic Disc Pit Maculaopathy
Status: COMPLETED
Conditions: Optic Disc Structural Anomaly|Maculopathy
Interventions: PROCEDURE: pars plana vitrectomy with internal limiting membrane (ILM) peeling
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TEMOkids Study : A Phase I Pediatric Study for KIMOZO, Oral Suspension of Temozolomide
Status: ACTIVE_NOT_RECRUITING
Conditions: Pediatric Cancer
Interventions: DRUG: Temozolomide Oral Suspension
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Effects of Different Physiotherapy and Rehabilitation Methods on Open Heart Surgery
Status: UNKNOWN
Conditions: Open Heart Surgery
Interventions: OTHER: Group A: Group routine cardiac rehabilitation program (RCRP)|OTHER: Group B: Group RCRP and inspiratory muscle training|OTHER: Group C: Group RCRP and virtual reality application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Trial to Evaluate the Efficacy, Safety, and Tolerability of Centanafadine Sustained-release Tablets in Adults With Attention-deficit/Hyperactivity Disorder
Status: COMPLETED
Conditions: Attention Deficit Disorder|Attention Deficit Hyperactivity Disorder
Interventions: DRUG: Centanafadine SR|OTHER: Placebo|DRUG: Centanafadine SR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Long-term Study of ERN/LRPT (Extended Release Niacin/Laropiprant [MK0524A]) in Patients With Dyslipidemia (0524A-102)
Status: COMPLETED
Conditions: Dyslipidemia
Interventions: DRUG: ER niacin (+) laropiprant (ERN/LRPT)|DRUG: ER niacin (+) laropiprant (ERN/LRPT)|DRUG: Extended-release niacin (ERN)|DRUG: Placebo to ERN/LRPT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Study of BMS-986165 in Healthy Subjects and to Treat Psoriasis
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: BMS-986165|DRUG: Interferon alpha-2a recombinant|DRUG: Famotidine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Electrophysiologic Changes in Blacks Treated With CBT for Insomnia
Status: COMPLETED
Conditions: Insomnia
Interventions: BEHAVIORAL: Cognitive Behavioral Therapy for Insomnia (CBT-I)|BEHAVIORAL: Self-Monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Preoperative Endoscopic Pancreatic Stent for Distal Pancreatectomy
Status: RECRUITING
Conditions: Pancreatectomy|Pancreatic Fistula
Interventions: PROCEDURE: Pancreatic Stenting|PROCEDURE: No Stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy of inControl Advice: A Decision Support System (DSS) for Diabetes
Status: COMPLETED
Conditions: Type1 Diabetes Mellitus
Interventions: DEVICE: Continuous Glucose Monitor (CGM)+Decision Support System (DSS)|OTHER: Continuous Glucose Monitor (CGM) alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Methotrexate With or Without Antineoplaston Therapy in Treating Postmenopausal Women With Advanced Refractory Breast Cancer
Status: WITHDRAWN
Conditions: Stage IV Breast Cancer|Recurrent Breast Cancer
Interventions: DRUG: antineoplaston A10|DRUG: methotrexate|PROCEDURE: alternative product therapy|PROCEDURE: biological therapy|PROCEDURE: biologically based therapies|PROCEDURE: cancer prevention intervention|PROCEDURE: chemotherapy|PROCEDURE: complementary and alternative therapy|PROCEDURE: differentiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Applicability of 3D-HDRA in Patients With Primary Liver Cancer: A Randomized Controlled Trial
Status: RECRUITING
Conditions: Liver, Cancer of, Primary Resectable
Interventions: DRUG: Oxaliplatin|DRUG: Doxorubicin|DRUG: Lobaplatin|DRUG: Cisplatin|DRUG: Oxaliplatin, Leucovorin, fluorouracil|DRUG: Lobaplatin, Raltitrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RCT of Meditation and Health Education on CIMT and MACE in Black Women and Men
Status: COMPLETED
Conditions: Cardiovascular Disease
Interventions: BEHAVIORAL: didactic health education control|BEHAVIORAL: Transcendental Meditation technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Feasibility Study of Intranasal Mesenchymal Trophic Factor (MTF) for Treatment of Asthma
Status: UNKNOWN
Conditions: Asthma
Interventions: BIOLOGICAL: Trophic factors from umbilical cord mesenchymal stem cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non Invasive Neurostimulation Technology for the Treatment of Type I Complex Regional Pain Syndrome (CRPS I)
Status: RECRUITING
Conditions: Type I Complex Regional Pain Syndrome
Interventions: DEVICE: Non-invasive Neuromodulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Assessments of a Peritoneal Dialysis Solution Containing Glucose, Xylitol, and L-Carnitine in CAPD
Status: TERMINATED
Conditions: End Stage Renal Disease
Interventions: DRUG: 1.5% Xylitol, 0.5% Glucose, and 0.02% L-carnitine|DRUG: 0.7% Xylitol, 0.5% Glucose, and 0.02% L-carnitine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Pembrolizumab (MK-3475) Versus Paclitaxel, Docetaxel, or Vinflunine for Participants With Advanced Urothelial Cancer (MK-3475-045/KEYNOTE-045)
Status: COMPLETED
Conditions: Urothelial Cancer
Interventions: BIOLOGICAL: pembrolizumab|DRUG: paclitaxel|DRUG: vinflunine|DRUG: docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: NOVOSYN® Quick Versus MONOSYN® Quick Suture Material in Resective Periodontal Surgery
Status: RECRUITING
Conditions: Gingivitis|Gingival Diseases|Periodontal Diseases
Interventions: DEVICE: Novosyn® in resective periodontal surgery|DEVICE: Monosyn® in resective periodontal surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cardiac Shock Wave Therapy for the Treatment of Myocardial Infarction With Non-obstructive Coronary Arteries
Status: RECRUITING
Conditions: Myocardial Infarction With Non-obstructive Coronary Arteries|Cardiac Shock Wave Therapy
Interventions: DEVICE: Cardiac Shock Wave Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: MK-7625A Plus Metronidazole Versus Meropenem in Pediatric Participants With Complicated Intra-Abdominal Infection (cIAI) (MK-7625A-035)
Status: COMPLETED
Conditions: Complicated Intra-Abdominal Infection
Interventions: DRUG: Ceftolozane/Tazobactam|DRUG: Metronidazole|DRUG: Meropenem|DRUG: Placebo for Metronidazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Testing Obeticholic Acid for Familial Adenomatous Polyposis
Status: RECRUITING
Conditions: Attenuated Familial Adenomatous Polyposis|Colorectal Carcinoma|Duodenal Carcinoma|Familial Adenomatous Polyposis
Interventions: PROCEDURE: Biopsy|PROCEDURE: Biospecimen Collection|PROCEDURE: Gastrointestinal Endoscopy|BIOLOGICAL: Obeticholic Acid|DRUG: Placebo Administration|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Steroid Sparing Potential Study of DGLA Cream in Patients With Moderate to Severe Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: DS107E|DRUG: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Observational Study Evaluating the Safety of NovoMix® in Type 2 Diabetes Patients Previously Treated With a Human Premix Insulin
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: biphasic insulin aspart 30|DRUG: biphasic insulin aspart 50|DRUG: biphasic insulin aspart 70
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Erector Spine Block for Back Surgery
Status: COMPLETED
Conditions: Spine Disease|Regional Anaesthesia
Interventions: PROCEDURE: erector spinae block|DRUG: Ropivacaine|PROCEDURE: Spine surgery|PROCEDURE: anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effect of Nebulized Budesonide and Oral Corticosteroids on Wheezing Episode Relapse in Children
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Nebulized Budesonide|DRUG: Usual care (albuterol with or without oral steroid)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effect of Ventilation on Cerebral Oxygenation in the Sitting Position
Status: COMPLETED
Conditions: Cerebral Ischemia
Interventions: OTHER: Hypocapnic group|OTHER: Normocapnic group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Fasting Study of Mercaptopurine 50 mg and Purinethol® Tablets 50 mg
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Mercaptopurine 50 mg|DRUG: Purinethol® Tablets 50 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Oestradiol Pre-treatment in an Ultrashort Flare GnRH Agonist/GnRH Antagonist Protocol in Poor Responders Undergoing IVF
Status: TERMINATED
Conditions: Infertility
Interventions: PROCEDURE: Oestradiol pre-treatment and combination of GnRH agonist/antagonist protocol|PROCEDURE: GnRH agonist or antagonist protocol without oestradiol pre-treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Efficacy Of S-1226 in Moderate Severity Covid-19 Bronchiolitis/Pneumonia
Status: SUSPENDED
Conditions: Covid19|SARS-CoV-2 Infection
Interventions: DRUG: S-1226
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparison of the Effects of Intraoperative Administration of Metoprolol or Esmolol on General Anesthetic Requirement
Status: COMPLETED
Conditions: Myocardial Ischemia
Interventions: DRUG: Metoprolol|DRUG: Esmolol|DRUG: P-Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER