pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Evaluation of Impact of AI Assistance on Workload Associated w Preparation of Rare Tumor Case Repts
Status: NOT_YET_RECRUITING
Conditions: Cognitive Burden|Cognitive Symptom
Interventions: BEHAVIORAL: Artificial Intelligence
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Docetaxel-based Chemoradiotherapy Plus Periradiation Chemotherapy Compared With INT 0116 Adjuvant Arm in Gastric Cancer
Status: UNKNOWN
Conditions: Gastric Cancer
Interventions: RADIATION: docetaxel-based chemoradiotherapy|RADIATION: FU-based chemoradiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: PRF and Bone Graft in Endodontic Surgeries
Status: COMPLETED
Conditions: Periapical; Infection
Interventions: BIOLOGICAL: Platelet Rich Fibrin|BIOLOGICAL: FDBA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess Safety and Tolerability of ASP1941 After Single and Repeated Administration in Healthy Subjects
Status: COMPLETED
Conditions: Healthy Volunteer|Pharmacokinetics of ASP1941
Interventions: DRUG: ASP1941|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: Neotililty Trial: Effect of Coenzyme Q10 on Semen Parameters in Men With Idiopathic Infertility
Status: WITHDRAWN
Conditions: Idiopathic Infertility
Interventions: DRUG: Coenzyme Q10
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Sulfamethoxazole-trimethoprim in the Treatment of Chronic Otitis Media
Status: COMPLETED
Conditions: Chronic Otitis Media
Interventions: DRUG: Sulfamethoxazole-trimethoprim|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mindfulness-based Intervention to Address PTSD in Trauma-exposed, Homeless Women
Status: COMPLETED
Conditions: Stress Disorders, Post-Traumatic|Depressive Symptoms|Hydrocortisone|Substance Use
Interventions: BEHAVIORAL: Modified Mindfulness-based Stress Reduction|BEHAVIORAL: Health Promotion Wellness Classes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase IV Study With a 36-week Extension Period to Evaluate the Efficacy and Safety of Dapagliflozin Therapy When Added to the Therapy of Japanese Patients With Type 2 Diabetes With Inadequate Glycemic Control on Insulin.
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Dapagliflozin 5 mg|DRUG: Placebo tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ultrasound-Guided Serratus Plane Block Vs Paravertebral Block For Chronic Post-mastectomy Pain.
Status: UNKNOWN
Conditions: Post-mastectomy Pain Syndrome
Interventions: PROCEDURE: serratus plane block by ultra-sound|PROCEDURE: paravertebral block by ultra-sound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Metabolic Preparation by a Low-carbohydrate Diet as Atkins-diet to Help in Detecting Infective Endocarditis by 18F-FDG PET
Status: COMPLETED
Conditions: Infective Endocarditis
Interventions: OTHER: Strict low carbohydrate diet (< 3gr/day of carbohydrate) before a 18F-FDG PET/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Targeting the Neurobiology of RRB in Autism Using N-acetylcysteine: Single-dose
Status: RECRUITING
Conditions: Autism Spectrum Disorder
Interventions: DRUG: N-Acetylcysteine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: StressLess Yoga Study
Status: COMPLETED
Conditions: Stress
Interventions: BEHAVIORAL: Yoga with High Breath work & meditation; Low movement/postures|BEHAVIORAL: Yoga with Low Breath work & meditation; High movement/postures
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of Pinatuzumab Vedotin (DCDT2980S) Combined With Rituximab or Polatuzumab Vedotin (DCDS4501A) Combined With Rituximab or Obinutuzumab in Participants With Relapsed or Refractory B-Cell Non-Hodgkin's Lymphoma (NHL)
Status: COMPLETED
Conditions: Follicular Lymphoma|Diffuse Large B-Cell Lymphoma
Interventions: DRUG: Obinutuzumab|DRUG: Pinatuzumab Vedotin|DRUG: Polatuzumab Vedotin|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Implant With an Acid-etched Fixture Surface and Internal-hex Collar May Achieve Greater Osseointegration.
Status: COMPLETED
Conditions: Jaw, Edentulous|Dental Implant
Interventions: DEVICE: Configuration 1|DEVICE: Configuration 2|DEVICE: Configuration 3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of PF-05212384 (Also Known as PKI-587)Administered Intravenously To Subjects With Solid Tumors
Status: COMPLETED
Conditions: Neoplasms
Interventions: DRUG: PF-05212384 (also known as PKI-587)
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Three Good Things 2020: a Brief Text-based Wellness Intervention
Status: COMPLETED
Conditions: Job Related Stress
Interventions: BEHAVIORAL: Three Good Things|BEHAVIORAL: Wait list control arm and then Three Good Things
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Ultrasound-guided PVB
Status: TERMINATED
Conditions: Thoracotomy Surgery|Anesthesia|Ultrasound-guided PVB|Post-operative Pain
Interventions: DEVICE: ultrasoundguided paravertebral catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HEalth Advocate for Liver Transplantation: Improving Transition of Care for Adolescent Liver Transplant Recipients
Status: RECRUITING
Conditions: Liver Transplant; Complications|Pediatric ALL
Interventions: BEHAVIORAL: Health Advocate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Prevention of Pocket Hematoma After Implantation Cardiovascular Implanted Electronic Devices
Status: UNKNOWN
Conditions: Hematoma Postoperative|Cardiac Resynchronization Therapy Devices|Compression Bandages
Interventions: DEVICE: pocket compression fixation belt
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Longitudinal Assessment of Arthralgia and Related Symptoms in Breast Cancer Patients Receiving Aromatase Inhibitors
Status: TERMINATED
Conditions: Breast Cancer
Interventions: BEHAVIORAL: Questionnaire|OTHER: Phone Calls
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Vitamin/Mineral Supplement for Children and Adults With Autism
Status: COMPLETED
Conditions: Autism
Interventions: DIETARY_SUPPLEMENT: Multi-Vitamin/Mineral Supplement|OTHER: Liquid Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase IIA Study in Patients With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: AZD2624|DRUG: Olanzapine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Tacrolimus Formulation and Glucose Metabolism After Kidney Transplantation (TAGLUMET Trial)
Status: COMPLETED
Conditions: Posttransplant Diabetes Mellitus
Interventions: DRUG: LCP-tacrolimus|DRUG: twice-daily tacrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improving Clinical Trial Awareness in NSCLC: Pilot Testing A Novel Healthcare IT Platform for Incorporating Education at the Point of Care
Status: COMPLETED
Conditions: Non-Small Cell Lung Carcinoma (NSCLC)
Interventions: OTHER: Survey
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Role of 5-Aminolevulinic Acid Fluorescence-Guided Surgery in Head and Neck Cancers: a Pilot Trial
Status: RECRUITING
Conditions: Neoplasm|Skull Base Neoplasm
Interventions: DRUG: 5-Aminolevulinic acid Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: PRospective rEgistry OF Advanced Stage cancER (PREFER) Patients to Assess Prevalence of Actionable Biomarkers and Driver Mutations to Address Disparities in Precision Medicine
Status: RECRUITING
Conditions: Lung Cancer|Ovarian Cancer|Uterine Cancer|Colorectal Cancer|Stomach Cancer|Esophageal Cancer|Pancreatic Cancer|Melanoma|Breast Cancer|Head and Neck Cancer|Soft Tissue Sarcoma|Rhabdomyosarcoma|Prostate Cancer
Interventions: DIAGNOSTIC_TEST: OmniSeq Test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: UMCC 9609 Tretinoin in Preventing Cancer of the Cervix in Patients With Cervical Neoplasia
Status: COMPLETED
Conditions: Cervical Cancer|Precancerous/Nonmalignant Condition
Interventions: DRUG: tretinoin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: PREVENTION
Clinical trial: Trial and Cost Effectiveness Evaluation of Intra-arterial Thrombectomy in Acute Ischemic Stroke
Status: TERMINATED
Conditions: Cerebral Stroke|Cerebrovascular Accident
Interventions: DRUG: Alteplase (rt-PA)/Actilyse|PROCEDURE: Mechanic thrombectomy (MERCI, PENUMBRA, CATCH, SOLITAIRE)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect on the Older's Cognition of Dual-loop Target Controlled Infusion Guided by Narcotrend Index
Status: UNKNOWN
Conditions: Anesthesia
Interventions: DEVICE: Dual-Loop TCI|DEVICE: Open-Loop TCI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nivolumab Plus FOLFOXIRI/Bevacizumab in First Line Chemotherapy of Advanced Colorectal Cancer RASm/BRAFm Patients
Status: UNKNOWN
Conditions: Colorectal Cancer
Interventions: DRUG: Nivolumab|DRUG: Bevacizumab|DRUG: Irinotecan|DRUG: Oxaliplatin|DRUG: Leucovorin|DRUG: fluoruracil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Perfluorohexylcotane (NOV03) for the Treatment of Signs and Symptoms of Dry Eye Disease Associated With Meibomian Gland Dysfunction (Gobi Study)
Status: COMPLETED
Conditions: Dry Eye Disease (DED)
Interventions: DRUG: NOV03|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment Optimization in Patients With Untreated Multiple Myeloma
Status: TERMINATED
Conditions: Multiple Myeloma
Interventions: DRUG: Lenalidomide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Losartan Potassium (100 mg Tablet) [Test Formulation, Torrent Pharmaceuticals Ltd., India] Versus Cozaar® (100 mg Tablet) [Reference Formulation, Merck & Co. Inc., USA] in Healthy Human Volunteers Under Fed Condition
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Losartan Potassium Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose:
Clinical trial: A Study to Evaluate 2 Doses Of Oral Administration Of Laquinimod Compared to Interferon ß-1a Administered by Injection in Participants With Relapsing Remitting Multiple Sclerosis (RRMS)
Status: WITHDRAWN
Conditions: Relapsing Remitting Multiple Sclerosis
Interventions: DRUG: Laquinimod|DRUG: Avonex®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Autologous Mitochondrial Transfer in ICSI to Improve Oocyte and Embryo Quality in IVF Patients. Pilot Study
Status: COMPLETED
Conditions: Infertility
Interventions: OTHER: Autologous mitochondria with ICSI|OTHER: STANDARD ICSI PROCEDURE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A 12-week, Randomized, Double-masked, Parallel Group Comparison of Evening Dosing With Xalacom in Subjects With Glaucoma
Status: COMPLETED
Conditions: Open Angle Glaucoma|Ocular Hypertension
Interventions: DRUG: Xalacom|DRUG: Xalatan|DRUG: Timolol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of a Booster Dose of New Formulations of GlaxoSmithKline Biologicals' DTPa-HBV-IPV/Hib Vaccine (GSK217744)
Status: COMPLETED
Conditions: Acellular Pertussis|Hepatitis B|Haemophilus Influenzae Type b|Tetanus|Diphtheria|Poliomyelitis
Interventions: BIOLOGICAL: Infanrix hexa|BIOLOGICAL: Prevenar 13|BIOLOGICAL: GSK217744
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of Ciprofol in Laparoscopic Sleeve Gastrectomy
Status: COMPLETED
Conditions: Bariatric Surgery
Interventions: DRUG: Ciprofol|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bortezomib and Temozolomide in Treating Patients With Advanced Refractory Solid Tumors or Melanoma
Status: TERMINATED
Conditions: Brain and Central Nervous System Tumors|Melanoma|Solid Tumor
Interventions: DRUG: PS-341 (VELCADE)|DRUG: temozolomide|OTHER: immunoenzyme technique|DRUG: PS-341 (VELCADE)|DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy Compared With Mitoxantrone in Treating Older Patients With Advanced Breast Cancer
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: DRUG: CMF regimen|DRUG: cyclophosphamide|DRUG: fluorouracil|DRUG: methotrexate|DRUG: mitoxantrone hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Treatment of Lateral Elbow Tendinopathy
Status: COMPLETED
Conditions: Epicondylitis, Lateral Humeral
Interventions: OTHER: Strength Training|PROCEDURE: Placebo|DRUG: Cortico-Steroid Injection. Depomedrol 40mg/1ml.|PROCEDURE: Dry Needling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intra-articular Pulsed Radiofrequency Neuromodulation Versus Intra-articular Steroids for Painful Knee Osteoarthritis
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: PROCEDURE: Pulse Radiofrequency|PROCEDURE: Standard of Care Intra- Articular Injection|PROCEDURE: Placebo Intra-Articular Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Test and Reference 400 mg Ibuprofen Coated Tablets in Healthy Volunteers
Status: COMPLETED
Conditions: Bioequivalence|Healthy Subjects
Interventions: DRUG: Darfen 400, 400 mg ibuprofen coated tablets (512 mg ibuprofen sodium dihydrate)|DRUG: Nurofen® Forte Express, 400 mg ibuprofen coated tablets (512 mg ibuprofen sodium dihydrate)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Perioperative Dexamethasone Reduces Postoperative Pain and Nausea After Hip Arthroscopy
Status: COMPLETED
Conditions: Pain, Postoperative|Nausea, Postoperative|Opioid Use
Interventions: DRUG: Dexamethasone 4mg|DRUG: NaCl 0.9%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intra-articular Injection Versus Normal Rehabilitation Therapy on Temporomandibular Joint Dysfunction
Status: NOT_YET_RECRUITING
Conditions: Temporomandibular Joint Dysfunction
Interventions: BEHAVIORAL: Routine rehabilitation treatment|PROCEDURE: Intra-articular Injection|DRUG: Lidocaine Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 'Dialogue and Guidance' - a Policy Intervention for Improved OHS Among Workplaces With WEA Violations
Status: UNKNOWN
Conditions: Occupational Diseases|Occupational Injuries|Safety Issues
Interventions: BEHAVIORAL: Treatment as usual|BEHAVIORAL: Dialogue and guidance over telephone|BEHAVIORAL: Dialogue and guidance at physical meeting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Intrapartum Sildenafil in Laboring Mothers
Status: NOT_YET_RECRUITING
Conditions: Neonatal Asphyxia|Intrapartum Fetal Distress|Development, Infant|Intrapartum Asphyxia
Interventions: DRUG: Sildenafil 50 mg Oral Tablet|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Robotic Cochlear Implantation on Hearing Performance in Noise
Status: NOT_YET_RECRUITING
Conditions: Severe to Profound Hearing Loss
Interventions: PROCEDURE: Surgery with RobOtol®|PROCEDURE: Conventional manual surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Aspirin Reload Before Percutaneous Coronary Intervention: Reperfusion Indexes Evaluation.
Status: COMPLETED
Conditions: Coronary Arteriosclerosis
Interventions: DRUG: Aspirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intra-Arrest-Ventilation in Human Cadavers
Status: NOT_YET_RECRUITING
Conditions: Cardiac Arrest
Interventions: OTHER: Endotracheal Intubation|OTHER: Laryngeal tube|OTHER: Laryngeal mask|OTHER: I-Gel-Laryngeal Mask
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Palonosetron Versus Ondansetron for the Prevention of Nausea and Vomiting
Status: COMPLETED
Conditions: Acute Myelogenous Leukemia|Chemotherapy-induced Nausea and Vomiting
Interventions: DRUG: Ondansetron|DRUG: Palonosetron
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: PET Imaging of Brain mGluR5 Receptors Using [18F]SP203
Status: COMPLETED
Conditions: Healthy|Glutamate Receptor|mGlur5 Protein|Excitatory Amino Acid Receptors|Drug Kinetics|PET Scan
Interventions: DRUG: [18F]SP203
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Cilengitide and Whole-Brain Radiation Therapy in Treating Patients With Brain Metastases From Lung Cancer
Status: COMPLETED
Conditions: Brain and Central Nervous System Tumors|Lung Cancer
Interventions: DRUG: cilengitide|OTHER: pharmacological study|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TLR4 Agonist GLA-SE and Radiation Therapy in Treating Patients With Soft Tissue Sarcoma That Is Metastatic or Cannot Be Removed by Surgery
Status: COMPLETED
Conditions: Stage III Adult Soft Tissue Sarcoma|Stage IV Adult Soft Tissue Sarcoma
Interventions: OTHER: Laboratory Biomarker Analysis|RADIATION: Radiation Therapy|DRUG: TLR4 Agonist GLA-SE
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Salvage Therapy With Sunitinib,Docetaxel and Platinum on Metastatic or Unresectable Non Small Cell Lung Cancer
Status: UNKNOWN
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: sunitinib, docetaxel, cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clopidogrel Aspirin Therapy (CAT) Versus Apixiban Aspirin Therapy (AAT) After Lower Limb Revascularization
Status: COMPLETED
Conditions: Ischemia|Anticoagulants
Interventions: DRUG: Combination drug
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Double-Blind Placebo Controlled Study of Adjunctive Aripiprazole for Symptomatic Hyperprolactinemia In Premenopausal Women With Schizophrenia
Status: COMPLETED
Conditions: Hyperprolactinemia
Interventions: DRUG: Aripiprazole|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of XmAb®23104 in Subjects With Selected Advanced Solid Tumors (DUET-3)
Status: COMPLETED
Conditions: Melanoma (Excluding Uveal Melanoma)|Cervical Carcinoma|Pancreatic Carcinoma|Breast Carcinoma That is Estrogen Receptor, Progesterone Receptor, and Her2 Negative|Hepatocellular Carcinoma|Urothelial Carcinoma|Squamous Cell Carcinoma of the Head and Neck|Nasopharyngeal Carcinoma|Renal Cell Carcinoma|Colorectal Carcinoma|Endometrial Carcinoma|Non-small Cell Lung Carcinoma|Small Cell Lung Cancer|Gastric or Gastroesophageal Junction Adenocarcinoma|Advanced Solid Tumors|Undifferentiated Pleomorphic Sarcoma
Interventions: BIOLOGICAL: XmAb®23104|BIOLOGICAL: Yervoy® (ipilimumab)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Green Tea Extract on Arterial Stiffness in Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: green tea extract|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The WORKER Study: Escitalopram and Telephone-based Cognitive Behaviour Therapy (CBT) for Depressed Working People
Status: COMPLETED
Conditions: Major Depressive Disorder (MDD)
Interventions: BEHAVIORAL: Telephone-based Cognitive Behaviour Therapy (CBT)|BEHAVIORAL: Telephone reminder calls
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Research Study of a New Medicine (NNC0650-0013) in Healthy Men
Status: RECRUITING
Conditions: Healthy Participants
Interventions: DRUG: NNC0650-0013 A|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An 8-Week Study to Evaluate Tenapanor in the Treatment of Hyperphosphatemia in End-Stage Renal Disease Patients on Hemodialysis (ESRD-HD)
Status: COMPLETED
Conditions: Hyperphosphatemia
Interventions: DRUG: Tenapanor|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Bobath/Halliwick on Children With Cerebral Palsy
Status: ACTIVE_NOT_RECRUITING
Conditions: Cerebral Palsy
Interventions: OTHER: Halliwick Concept
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Yili "Changqing" Pro-ABB Yoghurt in the Improvement of Human Gastrointestinal Tract System
Status: COMPLETED
Conditions: Constipation|Dyspepsia|Flatulence|Abdominal Pain
Interventions: DIETARY_SUPPLEMENT: Placebo yoghurt|DIETARY_SUPPLEMENT: Yili "Chang Qing" Pro-ABB yoghurt (Formula 1)|DIETARY_SUPPLEMENT: Yili "Chang Qing" Pro-ABB yoghurt (Formula 2)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Fingolimod Effect on Cytokine and Chemokine Levels
Status: COMPLETED
Conditions: Relapsing Remitting Multiple Sclerosis
Interventions: DRUG: Fingolimod 0.5 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of TNM002 in Chinese Healthy Adults
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: TNM002|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: In Vivo Assessment of Natural Tooth Color After Orthognathic Surgery. A Pilot Controlled Clinical Trial
Status: COMPLETED
Conditions: Discoloration, Tooth
Interventions: PROCEDURE: Combined orthodontic-orthognathic treatment|PROCEDURE: Standard orthodontic treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: The Efficacy of Potassium-competitive Acid Blocker in Patients With Laryngopharyngeal Reflux Disease
Status: COMPLETED
Conditions: Laryngopharyngeal Reflux Disease
Interventions: DRUG: Tegoprazan|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Prevention of Postpartum Depression: A Pilot Placebo-controlled Trial of Trazodone
Status: UNKNOWN
Conditions: Postpartum Depression
Interventions: DRUG: Trazodone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Changes in Breast Density and Blood Hormone Levels in Postmenopausal Women Receiving Anastrozole or Exemestane for Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: GENETIC: polymorphism analysis|OTHER: high performance liquid chromatography|OTHER: laboratory biomarker analysis|PROCEDURE: radiomammography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Chronic Thalidomide Administration in Patients Undergoing Chemoembolization for Unresectable Hepatocellular Cancer
Status: UNKNOWN
Conditions: Liver Cancer
Interventions: DRUG: thalidomide|PROCEDURE: chemoembolization with doxorubicin/collagen
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neratinib in Treating Older Patients With Stage IV HER2-Positive Breast Cancer
Status: COMPLETED
Conditions: HER2 Positive Breast Carcinoma|Stage IV Breast Cancer AJCC v6 and v7
Interventions: OTHER: Comprehensive Geriatric Assessment|OTHER: Laboratory Biomarker Analysis|DRUG: Neratinib|OTHER: Pharmacological Study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Safety and Tolerability of SerpinPC in Healthy Men and in Men With Severe Blood Disorders (Haemophilia A and B)
Status: ACTIVE_NOT_RECRUITING
Conditions: Hemophilia A|Hemophilia B
Interventions: DRUG: SerpinPC|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Vitamin D Supplementation in Patients With Severe and Extremely Severe COVID-19
Status: COMPLETED
Conditions: SARS-CoV2 Infection
Interventions: DIETARY_SUPPLEMENT: Vitamin D (cholecalciferol)|DIETARY_SUPPLEMENT: Herbal oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: PECS Block With Bupivacaine Vs Bupivacaine and Dexmedetomidine in Modified Radical Mastectomy
Status: UNKNOWN
Conditions: Anesthesia
Interventions: OTHER: General anesthesia (GA).|OTHER: PECS block using bupivacaine .|OTHER: PECS block using bupivacaine and dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Helical Blade vs Lag Screw Fixation for Cephalomedullary Nailing of Low Energy Intertrochanteric Hip Fractures
Status: UNKNOWN
Conditions: Hip Fractures
Interventions: DEVICE: Osteosynthesis with Trochanteric Fixation Nail (TFN), using a lag screw as a proximal fixation.|DEVICE: Osteosynthesis with Trochanteric Fixation Nail (TFN), using a helical blade as a proximal fixation.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radiofrequency Ablation Combined With Toripalimab and Lenvatinib in the Treatment of Short-term Recurrent Hepatocellular Carcinoma.
Status: NOT_YET_RECRUITING
Conditions: Recurrent Hepatocellular Cancer
Interventions: DRUG: toripalimab|DRUG: Lenvatinib|DEVICE: Radiofrequency ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination of Osimertinib and Aspirin to Treat Osimertinib Resistance Non-small Cell Lung Cancer ( NSCLC)
Status: UNKNOWN
Conditions: Non-Small Cell Lung Cancer Stage IIIB|Non-small Cell Lung Cancer Stage IV|EGFR T790M
Interventions: DRUG: Aspirin|DRUG: Osimertinib
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Neural Mobilization Versus PNF Hold Relax Technique on Lower Extremity in Hemiplegic Stroke
Status: COMPLETED
Conditions: Hemiplegic Stroke
Interventions: OTHER: Neural mobilization|OTHER: PNF hold relax technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effects of Yoga on Pulmonary Parameters, Posture, Body Awareness and Quality of Life Among Chronic Smokers
Status: COMPLETED
Conditions: Smoking
Interventions: OTHER: Asana Practice|OTHER: Pranayam Practice (Rhythmic regulated breathing)|BEHAVIORAL: Smoking Education Program
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Impact of DuoTherm on Opioid Use and Chronic Low Back Pain
Status: ACTIVE_NOT_RECRUITING
Conditions: Opioid-use Disorder|Chronic Low-back Pain|Opioid Use|Opioid Dependence
Interventions: DEVICE: Duotherm VibraCool Back Device|DEVICE: TENS 8-channel unit
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: STaR Trial: Multiple Ligament Knee Injuries
Status: RECRUITING
Conditions: Knee Dislocations|Multiple Ligament Knee Injuries
Interventions: PROCEDURE: Early Surgery|PROCEDURE: Delayed Surgery|PROCEDURE: Early Rehab|PROCEDURE: Delayed Rehab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating Safety and Efficacy of JCAR017 in Subjects With Relapsed or Refractory Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Lymphoma (SLL)
Status: RECRUITING
Conditions: Leukemia, Lymphocytic, Chronic, B-Cell|Lymphoma, Small Lymphocytic
Interventions: BIOLOGICAL: JCAR017 (lisocabtagene maraleucel)|BIOLOGICAL: JCAR017 (lisocabtagene maraleucel) + ibrutinib|BIOLOGICAL: JCAR017 (lisocabtagene maraleucel) + venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of Upadacitinib in Participants With Takayasu Arteritis (TAK)
Status: ACTIVE_NOT_RECRUITING
Conditions: Takayasu Arteritis (TAK)
Interventions: DRUG: Upadacitinib|DRUG: Placebo for Upadacitinib|DRUG: Prednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Umbilical Cord Mesenchymal Stem Cells Transplantation Combined With Plasma Exchange for Patients With Liver Failure
Status: UNKNOWN
Conditions: Liver Failure
Interventions: OTHER: Conventional plus UC-MSC treatment|OTHER: Conventional plus PE treatment|OTHER: Conventional plus UC-MSC and PE therapy|OTHER: Conventional treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transgender Men and HIV in Uganda: PrEP Uptake and Persistence
Status: COMPLETED
Conditions: HIV|Sexually Transmitted Infections|PrEP|Transgender Men
Interventions: DRUG: Lamivudine-Tenofovir 300 Mg-300 Mg Oral Tablet
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Doxorubicin vs. Trabectedin Plus Doxorubicin in Non Operable and/or Metastatic STS
Status: TERMINATED
Conditions: Sarcoma
Interventions: DRUG: Doxorubicin|DRUG: Trabectedin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BBV152/BBV154 Heterologus Prime-Boost Study
Status: COMPLETED
Conditions: Corona Virus Infection
Interventions: BIOLOGICAL: COVAXIN(BBV152)|BIOLOGICAL: BBV154 Intranasal Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: T-cells Expressing Anti-CD19 CAR in Pediatric and Young Adults With B-cell Malignancies
Status: UNKNOWN
Conditions: Acute Lymphoblastic Leukemia, B-precursor|Non-Hodgkin Lymphoma, B-cell
Interventions: BIOLOGICAL: CD19 CAR T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Percutaneous Dilatational Tracheostomy and Thyroid Isthmus Penetration
Status: ENROLLING_BY_INVITATION
Conditions: Tracheostomy Complication
Interventions: PROCEDURE: percutaneous dilatational tracheostomy (PDTS)|DIAGNOSTIC_TEST: Ultrasound examination|DIAGNOSTIC_TEST: Bronchoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Phase 4 Study of Brodalumab (KHK4827) in Subjects With Moderate to Severe Plaque Psoriasis
Status: WITHDRAWN
Conditions: Moderate to Severe Plaque Psoriasis
Interventions: DRUG: KHK4827-Active|DRUG: KHK4827-Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Epoetin Alfa With or Without Dexamethasone in Treating Fatigue and Anemia in Patients With Hormone-Refractory Prostate Cancer
Status: COMPLETED
Conditions: Anemia|Fatigue|Prostate Cancer
Interventions: BIOLOGICAL: epoetin alfa|DRUG: dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Mood and Cognitive Effects of Psilocybin in Healthy Participants
Status: WITHDRAWN
Conditions: Mood Disturbance|Mood Change|Sleep Disturbance|Drug Effect|Psychedelic Experiences|Health, Subjective|Psilocin Toxicity|Psilocybin Toxicity|Psilocybin Causing Adverse Effects in Therapeutic Use|Anxiety
Interventions: DRUG: Psilocybin|DRUG: Inonotus Obliquus Whole Extract
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dexmedetomidine Hydrochloride in the Prevention of Organ Failure Following Severe Acute Pancreatitis
Status: UNKNOWN
Conditions: Pancreatitis, Acute Necrotizing
Interventions: DRUG: Infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The INSIGHT Feasibility Study Ultrasound in the Intensive Care Unit: A Randomised Controlled Feasibility Trial
Status: NOT_YET_RECRUITING
Conditions: Critical Illness|Cardiac Complication|Pleural Effusion|Consolidation|Ascites|Thrombosis
Interventions: DIAGNOSTIC_TEST: Whole body point of care ultrasound scan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparison of Oxygen Controllers in Preterm InfanTs
Status: TERMINATED
Conditions: Premature Infant|Respiratory Insufficiency|Hypoxia|Hyperoxia
Interventions: DEVICE: Automated oxygen control by the CLiO2 algorithm|DEVICE: Automated oxygen control by the Oxygenie algorithm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Change of Dual Antiplatelet Therapy in Patients With Acute Coronary Syndrome
Status: COMPLETED
Conditions: Acute Coronary Syndrome|Percutaneous Coronary Intervention|Drug-Eluting Stents
Interventions: DRUG: Clopidogrel|DRUG: Ticagrelor
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Feasibility of a Self-Efficacy Ecological Momentary Intervention (EMA) App
Status: ACTIVE_NOT_RECRUITING
Conditions: Self Efficacy
Interventions: BEHAVIORAL: Self-Efficacy Training and Ecological Momentary Assessment|BEHAVIORAL: Control intervention: Ecological Momentary Assessment only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity of Gardasil-9 HPV Vaccine in People Living With HIV
Status: RECRUITING
Conditions: Papillomavirus Vaccines|Human Immunodeficiency Virus|Papillomavirus Infection|Serology|Cervical Intraepithelial Neoplasia|Anal Intraepithelial Neoplasia|Oral Cavity Infection
Interventions: BIOLOGICAL: Human papillomavirus 9-valent vaccine, recombinant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evolocumab Versus LDL Apheresis in Patients With Hypercholesterolemia
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DRUG: evolocumab|DRUG: evolocumab and LDL apheresis|PROCEDURE: LDL apheresis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 2 Years Prospective Study to Collect Real-life Data on the Retention, Quality of Life, Effectiveness and Treatment Pattern of Secukinumab in Adult Patients With Moderate to Severe Plaque Psoriasis, Psoriatic Arthritis, Ankylosing Spondylitis and Non-radiographic Axial Spondyloarthritis
Status: ACTIVE_NOT_RECRUITING
Conditions: Moderate to Severe Plaque Psoriasis|Psoriatic Arthritis|Ankylosing Spondylitis|Non-radiographic Axial Spondyloarthritis
Interventions: OTHER: secukinumab
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Health Benefits of Functional Oil (Mega 3 Fatty Acids From Fish Oil) on Obese People
Status: COMPLETED
Conditions: Obesity
Interventions: DIETARY_SUPPLEMENT: functional oil|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Community Trial for Visceral Leishmaniasis (VL)
Status: COMPLETED
Conditions: Visceral Leishmaniasis
Interventions: DRUG: Albendazole, Iron, Zinc and Vitamin A|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: How Does Iron Supplementation Affect Training and Performance in Female Collegiate Rowers?
Status: COMPLETED
Conditions: Iron Deficiency (Without Anemia)
Interventions: DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: Ferrous sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of the Effects of Advanced Exercise Treatment Performed Under the Supervision of a Physiotherapist and Provided as a Home Program on Adduction Angle, Pain, Functional Status, Quality of Life and Kinesophobia in Individuals With Hallux Valgus
Status: UNKNOWN
Conditions: Exercise|Hallux Valgus
Interventions: OTHER: Stretching the intrinsic muscles|OTHER: Thumb Abduction with MTF Joint Traction|OTHER: Thumb active extension exercise|OTHER: Toe spread out|OTHER: Short foot|OTHER: Heel rise|OTHER: Towel toe curl|OTHER: Gastrocnemius active static stretching exercise|OTHER: Plantar fascia and gastrocnemius stretching exercise on step
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GPI 15715 For Sedation in the Intensive Care Unit (ICU) Setting
Status: COMPLETED
Conditions: Postoperative Sedation|Intubation|Respiration, Artificial
Interventions: DRUG: AQUAVAN (fospropofol disodium; GPI 15715 )
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bright IDEAS for Pediatric Palliative Care: A Problem-Solving Skills Intervention to Empower Parent Resilience
Status: RECRUITING
Conditions: Psychological Distress|Quality of Life
Interventions: BEHAVIORAL: Bright IDEAS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: SAD Study of APR002 Investigating the Safety/Tolerability, Pharmacokinetics/Pharmacodynamics in Healthy Subjects
Status: COMPLETED
Conditions: COVID-19
Interventions: DRUG: APR002|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study Evaluating AGG-523 in Subjects With Severe Osteoarthritis Requiring Total Knee Replacement
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DRUG: AGG-523 (Aggrecanase Inhibitor)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Benefits of the Xiaxi Postural Hammock and a Xiaxi Exercise Program
Status: COMPLETED
Conditions: Chronic Pain|Low Back Pain|Exercise
Interventions: DEVICE: Xiaxi postural hammock|BEHAVIORAL: Yoga mat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Family-Focused Treatment Plus Pharmacotherapy for Bipolar Disorder in Adolescents
Status: COMPLETED
Conditions: Bipolar Disorder
Interventions: BEHAVIORAL: Family-Focused Treatment Plus Pharmacotherapy|BEHAVIORAL: Enhanced Care Plus Pharmacotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Testogel® in Men With Partial Androgen Deficiency of Aging Males (PADAM)
Status: COMPLETED
Conditions: Androgens (Deficiency)|Male
Interventions: DRUG: Testogel (Testosterone, BAYV001915)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating IGSC 20% Flexible Dosing in Treatment-Experienced and Treatment-Naive Subjects With Primary Immunodeficiency
Status: WITHDRAWN
Conditions: Primary Immunodeficiency
Interventions: BIOLOGICAL: IGSC 20% daily push versus every 2 weeks pump|BIOLOGICAL: IGSC 20% daily push versus once a week pump|BIOLOGICAL: IGSC 20% daily push versus 2 times per week pump|BIOLOGICAL: IGSC 20% 150 mg/kg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Safety and Effectiveness of Interferon-Free Treatment of Hepatitis C Virus Infection in HIV-Coinfected Adults on Antiretroviral Therapy
Status: TERMINATED
Conditions: HIV Infections|Hepatitis C
Interventions: DRUG: Paritaprevir/ritonavir/ombitasvir (PTV/r/OBT)|DRUG: Dasabuvir (DSV)|DRUG: Ribavirin (RBV)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT