pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Impact of Pantoprazole on 24-H Glycemic Control and on Post-prandial Glucose Excursion in Patients With Type 2 Diabetes
Status: UNKNOWN
Conditions: Diabetes Mellitus
Interventions: DRUG: Pantoprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: DYNAmic Immune Microenvironment of HCC Treated With atezolIzumab Plus bevaCizumab
Status: RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Aatezolizumab plus Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Relaxation and Meditation Techniques on Pain, Fatigue and Quality of Life
Status: COMPLETED
Conditions: Neuropathy, Diabetic
Interventions: BEHAVIORAL: Progressive muscle relaxation|BEHAVIORAL: Mindfulness meditation|OTHER: Attention matched control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pilot Study Evaluating Stress Response and Immune Function in Mechanically Ventilated Patients With Alcohol Use Disorders Treated With Propofol or Midazolam
Status: WITHDRAWN
Conditions: Alcoholism|Respiration, Artificial
Interventions: DRUG: Propofol|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Phase Ib/II Trial to Evaluate the Safety and Efficacy of QL1706 in Patients With Advanced Hepatocellular Carcinoma
Status: RECRUITING
Conditions: Advanced Liver Cancer
Interventions: DRUG: QL1706|DRUG: QL1604|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasound Guided Sciatic Nerve Block
Status: COMPLETED
Conditions: Sciatic Nerve
Interventions: OTHER: Sciatic Nerve block|OTHER: Leg raised 30°|OTHER: Distal tourniquet placed on the lower part of the leg|OTHER: Leg in a neutral position
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Value of Cortactin Expression in Invasive and Non-invasive Urinary Bladder Urothelial Carcinoma in Egyptian Population
Status: COMPLETED
Conditions: Urothelial Carcinoma
Interventions: GENETIC: Expression of Cortactin anti body
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of Efficacy and Tolerance of JOE on 4 to 11 Years Old Asthmatic Patients of GINA 2,3,4 and 5 Grades
Status: ACTIVE_NOT_RECRUITING
Conditions: Asthma in Children
Interventions: DEVICE: JOE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Gemcitabine With Oxaliplatin (GEMOX) in Patients With Advanced Hepatocellular Carcinoma After Failure of Sorafenib Treatment
Status: COMPLETED
Conditions: Hepatocellular Carcinoma, Unresectable, Advanced
Interventions: DRUG: Gemcitabine, Oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RECOVER-NEURO: Platform Protocol, Appendix_A to Measure the Effects of BrainHQ, PASC CoRE and tDCS Interventions on Long COVID Symptoms
Status: ACTIVE_NOT_RECRUITING
Conditions: Long COVID|Long Covid19|Long Covid-19
Interventions: OTHER: BrainHQ/Active Comparator Activity|OTHER: BrainHQ|OTHER: PASC CoRE|DEVICE: tDCS-active|DEVICE: tDCS-sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Early Feasibility Study of the CardiAQ™ TMVI System (Transfemoral and Transapical DS)
Status: WITHDRAWN
Conditions: Mitral Insufficiency|Heart Valve Disease|Cardiovascular Disease|Heart Disease
Interventions: DEVICE: CardiAQ TMVI System (Transapical & Transfemoral DS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessing the Clinical Utility of Adding Pentoxifylline to Neoadjuvant Chemotherapy Protocols in Breast Cancer Patients"
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer Female
Interventions: DRUG: Pentoxifylline Oral Tablet|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Amr Maneuver for Prevention of Postpartum Hemorrhage
Status: UNKNOWN
Conditions: Post Partum Hemorrhage
Interventions: DRUG: Oxytocin IV shot|DRUG: Oxytocin IV drip|PROCEDURE: Amr maneuver
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Using Drug Levels and Drug Resistance Testing to Select Effective Anti-HIV Drug Combinations in Patients With Drug-resistant HIV
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: lopinavir/ritonavir|DRUG: indinavir sulfate|DRUG: tenofovir disoproxil fumarate|DRUG: ritonavir|DRUG: fosamprenavir
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rapid Diagnosis of COVID-19 by Chemical Analysis of Exhaled Air
Status: COMPLETED
Conditions: Covid19
Interventions: DIAGNOSTIC_TEST: Performance evaluation (sensitivity and specificity) for COVID-19 diagnosis of the Vocus PTR-TOF process
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy, Safety, Tolerability and Pharmacokinetics of BIBN 4096 BS Versus Placebo in the Treatment of a Single Attack of Acute Migraine Headache
Status: COMPLETED
Conditions: Migraine Disorders
Interventions: DRUG: BIBN 4096 BS|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Effectiveness of Multifaceted Implementation Strategies for Implementing a Guideline for the Prevention of Common Mental Disorders at the Workplace in Schools
Status: COMPLETED
Conditions: Common Mental Disorders
Interventions: BEHAVIORAL: Multifaceted implementation strategies|BEHAVIORAL: Single implementation strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Dysphagia in Oculopharyngeal Muscular Dystrophy (OPMD)- Evaluation, Endoscopic Examination of Swallowing, Treatment and Long Term Follow up
Status: UNKNOWN
Conditions: Dysphagia
Interventions: PROCEDURE: Upper esophageal sphincter myotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of CC-122 to Assess the Safety and Tolerability in Japanese Patients With Advanced Solid Tumors and Non-Hodgkin's Lymphoma (NHL)
Status: COMPLETED
Conditions: Lymphoma, Non-Hodgkin
Interventions: DRUG: CC-122
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Oxaliplatin, Cytosine Arabinoside, Dexamethasone With Rituxan (ROAD) in Patients With Relapsed Non-Hodgkins Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: DRUG: Oxaliplatin, Cytosine Arabinoside, Dexamethasone With Rituxan (ROAD)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Respiratory Muscle Training by Spirotiger in Chronic Patients
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease|Congestive Heart Failure
Interventions: DEVICE: Spirotiger
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Probe-based Volumetric Laser Endomicroscopy (pVLE) of Endoscopic Mucosal Resection (EMR) Tissue in Patients With Barrett's Dysplasia
Status: COMPLETED
Conditions: Barrett's Esophagus With High Grade Dsyplasia|Early Esophageal Cancer
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of Pharmacokinetics and Safety of AJU-A51 in Healthy Adults
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: AJU-A51 Tab.|DRUG: A51R1 Tab. and A51R2 Tab.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non-Invasive Mechanical Ventilation in Elderly Patients
Status: TERMINATED
Conditions: Acute Respiratory Failure
Interventions: DEVICE: Non-invasive mechanical ventilation using a BiPAP Vision or any other ICU ventilators with NIV option|DRUG: standard medical therapy plus oxygen that includes salbutamol, prednisolone and antibiotics as needed|DRUG: standard medical therapy that includes salbutamol, prednisolone and antibiotics as needed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Quality of Life Between Patients Underwent Transoral Endoscopic Thyroid Surgery and Conventional Surgery
Status: UNKNOWN
Conditions: Quality of Life|Transoral Endoscopic Thyroidectomy|Conventional Thyroidectomy
Interventions: PROCEDURE: Transoral endoscopic thyroidectomy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Intranasal Dexmedetomidine vs Intranasal Midazolam as Anxiolysis Prior to Pediatric Laceration Repair
Status: COMPLETED
Conditions: Laceration|Anxiety
Interventions: DRUG: Dexmedetomidine|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Perioperative Analgesic Effect of Two Different Volumes of Local Anesthetic Solution in Erector Spinae Plane Block in Patients Undergoing Modified Radical Mastectomy
Status: RECRUITING
Conditions: Erector Spinae Plane Block|Modified Radical Mastectomy
Interventions: DRUG: Erector spinae plane block(15 ml bupivacaine 0.5%)|DRUG: Erector spinae plane block (15 ml bupivacaine 0.5% and 15ml normal saline)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Effect of Pharmacological Heart Rate Reduction on Visco-elastic Properties of the Arterial Wall (BRADYVASC)
Status: UNKNOWN
Conditions: Healthy|Vascular Stiffness|Aging
Interventions: DRUG: ivabradine|DRUG: lactose capsule (placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Bone Density Before and After Placement of Implant Using Osseodensification Technique
Status: NOT_YET_RECRUITING
Conditions: Evaluation of Osseointegration and Stability of Dental Implants in Bone Density Enhanced by Osseodensification Technique
Interventions: PROCEDURE: Osseodensification
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open Preperitoneal Mesh Versus Retromuscular Mesh Versus Suture Repair for Abdominal Wall Hernias
Status: UNKNOWN
Conditions: Ventral Hernia|Ventral Incisional Hernia|Umbilical Hernia
Interventions: PROCEDURE: Ventral hernia repair
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Scaling a Decision Aid on Prenatal Screening for Trisomy 21, 18 and 13
Status: RECRUITING
Conditions: Decision Aid
Interventions: OTHER: DA Scaling Strategies
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effects of Iloprost on Oxygenation During One-lung Ventilation in Supine-positioned Patients
Status: UNKNOWN
Conditions: Mediastinal Mass
Interventions: DRUG: 5ml of inhaled normal saline|DRUG: 20μg (2ml) of inhaled iloprost (Ventavis®) and 3ml of inhaled normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Olaptesed (NOX-A12) Alone and in Combination With Pembrolizumab in Colorectal and Pancreatic Cancer
Status: COMPLETED
Conditions: Metastatic Colorectal Cancer|Metastatic Pancreatic Cancer
Interventions: DRUG: Olaptesed pegol - Monotherapy|DRUG: Olaptesed pegol + Pembrolizumab - Combination Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stem Cell Transplantation for Hematological Malignancies
Status: TERMINATED
Conditions: Leukemia, Lymphocytic, Acute|AML|MDS
Interventions: PROCEDURE: Stem Cell Transplant|DRUG: Busulfan|DRUG: Cyclophosphamide|DRUG: Melphalan|DRUG: G-CSF|DRUG: ATG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: FitLink: Improving Weight Loss Maintenance by Using Digital Data to Provide Support and Accountability
Status: COMPLETED
Conditions: Obesity|Overweight|Overweight and Obesity|Weight Loss
Interventions: BEHAVIORAL: Gold Standard Behavior Therapy for Weight Loss|BEHAVIORAL: Standard Remote Behavior Therapy for Weight Loss|BEHAVIORAL: Digital Data Sharing Behavior Therapy for Weight Loss
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of CACICOL20 on Corneal Epithelial Healing After Cross-linking in Patients With Keratoconus
Status: COMPLETED
Conditions: Keratoconus
Interventions: DEVICE: RGTA OTR 4120 (CACICOL20)|DEVICE: Genteal HA eye drops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: rTMS in Overactive Bladder
Status: RECRUITING
Conditions: Overactive Bladder|Overactive Bladder Syndrome|Urge Incontinence|Urgency-frequency Syndrome|Urinary Incontinence|Urinary Incontinence, Urge
Interventions: DEVICE: Transcranial Magnetic Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Trial of Weight Bearing Status Following Femoral Revision With Tapered, Fluted, Titanium Stems
Status: UNKNOWN
Conditions: Postoperative Pain|Hip Arthroplasty
Interventions: PROCEDURE: immediate weight bearing after surgery|PROCEDURE: 6 weeks of toe-touch weight bearing after surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Effectiveness of Cartiva Implant in the Treatment of First CMC Joint Osteoarthritis Compared to LRTI (GRIP 2)
Status: UNKNOWN
Conditions: Osteoarthritis
Interventions: DEVICE: Cartiva
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Effects of Esketamine on Safety of On-road Driving in Healthy Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Esketamine|DRUG: Mirtazapine|DRUG: Placebo (Matched to Esketamine)|DRUG: Placebo (Matched to Mirtazapine)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Ipilimumab in Treating Patients With Relapsed or Refractory High-Risk Myelodysplastic Syndrome or Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome|Chronic Myelomonocytic Leukemia|Myelodysplastic Syndrome|Previously Treated Myelodysplastic Syndrome|Recurrent Adult Acute Myeloid Leukemia|Secondary Myelodysplastic Syndrome
Interventions: BIOLOGICAL: Ipilimumab|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Extended CPAP on Bronchopulmonary Dysplasia
Status: COMPLETED
Conditions: Bronchopulmonary Dysplasia|Prematurity
Interventions: OTHER: Protocolized weaning of respiratory support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Ventilator Adapters for Combivent Respimat
Status: TERMINATED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Combivent Respimat via tee adapter|DRUG: Combivent Respimat via ventilator adapter
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Acetazolamide for Reversal of Metabolic Alkalosis in Mechanically Ventilated Chronic Obstructive Pulmonary Disease Patients
Status: COMPLETED
Conditions: Decompensated Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Acetazolamide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics of Ingenol Mebutate Gel in Actinic Keratosis Under Maximum Use Conditions
Status: COMPLETED
Conditions: Actinic Keratosis
Interventions: DRUG: Ingenol mebutate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Amlodipine and Norvasc Under Fasting and FED Conditions in Chinese Healthy Volunteers
Status: COMPLETED
Conditions: Bioequivalence
Interventions: DRUG: LANDI-Amlodipine Besylate Tablet 5mg|DRUG: Norvasc Tablets 5mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Microbiome and Non-caloric Sweeteners in Humans
Status: COMPLETED
Conditions: Glucose Intolerance|Glucose, Low Blood|Glucose, High Blood
Interventions: DIETARY_SUPPLEMENT: Glucose|DIETARY_SUPPLEMENT: Aspartame|DIETARY_SUPPLEMENT: Sucralose|DIETARY_SUPPLEMENT: Saccharin|DIETARY_SUPPLEMENT: Stevia|OTHER: No Supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Fludarabine and Rituximab With or Without Pixantrone in Treating Patients With Relapsed or Refractory Indolent Non-Hodgkin Lymphoma
Status: WITHDRAWN
Conditions: Leukemia|Lymphoma
Interventions: BIOLOGICAL: rituximab|DRUG: fludarabine phosphate|DRUG: pixantrone dimaleate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: Patient Augmented Reality and Vibratory Array Otorhinolaryngology Procedures
Status: RECRUITING
Conditions: Pain, Acute|Vocal Fold Polyp|Vocal Cord Paralysis|Laryngeal Neoplasms
Interventions: OTHER: Vibroacoustic stimulation on|OTHER: Augmented Reality on|OTHER: Vibroacoustic stimulation off|OTHER: Augmented reality off
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effectiveness of Lubiprostone in Constipated Diabetics
Status: COMPLETED
Conditions: Constipation|Diabetes
Interventions: DRUG: Lubiprostone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: the Effect of Ozone Oil on the Postoperative Sequalae After Surgical Removal of Third Molar
Status: COMPLETED
Conditions: Impacted Third Molar Tooth
Interventions: DRUG: Ozone-Based Agent|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Chronic Exertional Compartment Syndrome (CECS) Treated With Abobotulinumtoxin A
Status: RECRUITING
Conditions: Compartment Syndrome of Leg
Interventions: DRUG: AbobotulinumtoxinA|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Recovery and Aftercare in Post Intensive Care Therapy Patients - RAPIT Study
Status: COMPLETED
Conditions: Intensive Care (ICU) Patients
Interventions: OTHER: Standardized Followup program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Psychological Prevention of Internalizing Disorders
Status: COMPLETED
Conditions: Anxiety Symptoms|Depressive Symptoms|Somatoform Symptoms
Interventions: BEHAVIORAL: Cognitive Behavioral Group Therapy|BEHAVIORAL: Cognitive Behavioral Group Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Esthetic, Clinical and Radiographic Outcomes of Immediately Placed Implants (Type 1) and Early Placed Implants (Type 2)
Status: COMPLETED
Conditions: Jaw, Edentulous, Partially|Acquired Absence of Single Tooth
Interventions: PROCEDURE: Placement of a dental implant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating Safety and Tolerability of Escalating Single and Multiple Doses of PIPE-791 and Food Effect in Healthy Volunteers
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DRUG: PIPE-791|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Efficacy and Pharmacokinetics of an Antifungal in Patients Undergoing Chemotherapy
Status: COMPLETED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Isavuconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Personalized Risk Estimation for Crohn's Disease (PRE-CD): Implementation and Feasibility
Status: NOT_YET_RECRUITING
Conditions: Inflammatory Bowel Diseases|Crohn Disease|Crohn Colitis|Crohn's Ileocolitis|Crohn's Gastritis|Crohn's Jejunitis|Crohn's Duodenitis|Crohn's Esophagitis
Interventions: BEHAVIORAL: Personalized Risk Estimation for Crohn's Disease (PRE-CD) tool|BEHAVIORAL: Standard Crohn's Disease Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Accuracy of Commercially Available Heart Rate Monitors III
Status: COMPLETED
Conditions: Cardiac Rehabilitation
Interventions: DEVICE: Fit Bit Blaze|DEVICE: Garmin Forerunner 235|DEVICE: Tom Tom Spark Cardio|DEVICE: Apple Watch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Comparison of Digital Intubation (Two-finger) and Video Laryngoscopy
Status: COMPLETED
Conditions: Intubated Patients
Interventions: DEVICE: Digital Intubation (Two-finger)|DEVICE: Video Laryngoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Duble Lumen Intubation
Status: COMPLETED
Conditions: Intubation;Difficult|Intubation; Difficult or Failed|Difficult Airway
Interventions: DEVICE: Standard double-lumen tube|DEVICE: Double-Lumen Tube Vivasight-DL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Adalimumab for the Induction of Clinical Remission in Japanese Subjects With Crohn's Disease
Status: COMPLETED
Conditions: Crohn's Disease
Interventions: BIOLOGICAL: adalimumab|BIOLOGICAL: adalimumab|BIOLOGICAL: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Myofascial Release With and Without Support Belt for Sacroiliac Joint Pain in Pregnant Females.
Status: COMPLETED
Conditions: Sacroiliac Joint Pain
Interventions: OTHER: Myofascial release|OTHER: pelvic Support belt
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tolerability/Safety and Efficacy of Inhaled AZD4818 in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: DRUG: AZD4818|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Brain Activity and Hormonal Changes During Food Administration
Status: COMPLETED
Conditions: Appetite Regulation
Interventions: DIETARY_SUPPLEMENT: Water with guar gum - Non Caloric|DIETARY_SUPPLEMENT: Chocolate milk - Oral Caloric|DIETARY_SUPPLEMENT: Chocolate milk - Intra Gastric Caloric
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of the Genome, Gut Metagenome and Lifestyle of Patients With Incident Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Metagenome|Genetic Predisposition
Interventions: DIAGNOSTIC_TEST: 16S rRNA gene sequencing|GENETIC: DNA-microarray genotyping
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Tourniquet on Sensory Nerve Conduction Threshold (sNCT) and OxyNeuroGram (ONG) Index- A Volunteer Study
Status: COMPLETED
Conditions: Sensory Nerve Conduction|Oxyneurogram Index
Interventions: DEVICE: tourniquet, sensory nerve conduction abnormality
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Managing Sleep Symptoms and Modifying Mechanisms of Traumatic Stress
Status: COMPLETED
Conditions: Stress Disorders, Post-Traumatic|Depression|Sleep
Interventions: BEHAVIORAL: Cognitive Behavioral Therapy|BEHAVIORAL: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Endoscopic Ultrasound-guided Ethanol Injection of Pancreatic Cystic Neoplasms
Status: COMPLETED
Conditions: Neoplasms, Cystic, Mucinous, and Serous
Interventions: DRUG: Ethanol|DRUG: Lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fluconazole Prophylaxis for the Prevention of Candidiasis in Infants Less Than 750 Grams Birthweight
Status: COMPLETED
Conditions: Candidiasis
Interventions: DRUG: fluconazole|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Type of Exercise and Education in Patients With SubAcromial Pain Syndrome
Status: COMPLETED
Conditions: Shoulder Pain
Interventions: PROCEDURE: Eccentric Strengthening|PROCEDURE: Traditional Strengthening|BEHAVIORAL: Pain education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Is Pulsed Ultrasound Treatment Effective in Knee Osteoarthritis
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: OTHER: Pulsed Ultrasound Treatment|OTHER: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Oral Microdose Lupron Versus Luteal Estradiol Trial in Poor Responder In Vitro Fertilization (IVF) Patients
Status: WITHDRAWN
Conditions: Infertility
Interventions: DRUG: Oral contraceptive pill and microdose lupron|DRUG: E2 patch/antagonist
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Intravesical Enfortumab Vedotin For Treatment of Patients With Non-muscle Invasive Bladder Cancer (NMIBC)
Status: RECRUITING
Conditions: Urinary Bladder Neoplasms|Carcinoma in Situ|Carcinoma Transitional Cell|Non-muscle Invasive Bladder Cancer|NMIBC
Interventions: DRUG: Enfortumab vedotin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Prognostic Value of Cervical Elastography for Identifying Patients at Risk for Preterm Delivery
Status: TERMINATED
Conditions: Obstetric Labor|Labor Onset|Obstetric Labor, Premature
Interventions: PROCEDURE: Cervical ultrasound +elastography 1|BIOLOGICAL: Vaginal fibronectin measurement|DRUG: Tocolytic treatment for 2 hours|PROCEDURE: Cervical ultrasound +elastography 2
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Feasibility Study of Closed Loop Control in Type 1 Diabetes Using Heart Rate Monitoring as an Exercise Marker
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus
Interventions: DEVICE: Heart rate informed SSM+HMM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Oral XIGO Tablets to Treat The Common Cold
Status: COMPLETED
Conditions: Common Cold
Interventions: DIETARY_SUPPLEMENT: lactoferrin, L-Glutamine and beta-glucans|DIETARY_SUPPLEMENT: Placebo Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Motor Imagery Intervention for Chronic Painful Shoulder in Primary Care
Status: UNKNOWN
Conditions: Shoulder Pain
Interventions: OTHER: Motor Imaginery and Action Observation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Vitamin D Deficiency in Intestinal Rehabilitation Clinic Patients With a Portable Ultraviolet B Lamp
Status: COMPLETED
Conditions: Vitamin D Deficiency|Short Bowel Syndrome
Interventions: DEVICE: Ultraviolet B lamp
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Dosage Regimens of Oral Dapsone for Prophylaxis of Pneumocystis Carinii Pneumonia in Pediatric HIV Infection
Status: COMPLETED
Conditions: Pneumonia, Pneumocystis Carinii|HIV Infections
Interventions: DRUG: Dapsone
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: LAMPP Trial for Peripheral and Cutaneous T-Cell Lymphoma
Status: TERMINATED
Conditions: T-Cell Lymphoma
Interventions: DRUG: Doxil, Methotrexate, L-Asparaginase, Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Relative Abuse Potential of Almorexant in Recreational Drug Users
Status: COMPLETED
Conditions: Abuse Potential Study
Interventions: DRUG: 200 mg almorexant|DRUG: 400 mg almorexant|DRUG: 1000 mg almorexant|DRUG: 20 mg zolpidem|DRUG: 40 mg zolpidem|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Human-centered Injury Thrivorship Pathway for Survivors of Physical Trauma
Status: NOT_YET_RECRUITING
Conditions: Injury Traumatic|Survivorship|Trauma Injury
Interventions: OTHER: Human-Centered Injury Thrivorship Pathway
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Confirm Rx™ Versus Reveal LINQ™ - Which is More Reliable in Data Transmission? A Randomized Clinical Study
Status: COMPLETED
Conditions: Cardiac Arrythmias|Syncope|Atrial Fibrillation|Atrial Flutter|Tachycardia|Stroke
Interventions: DEVICE: Abbott, Inc Confirm Rx™ versus Medtronic, Inc Reveal LINQTM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Administration of Low-level Laser on Muscles of Mastication Following the Induction of Initial Fatigue
Status: UNKNOWN
Conditions: Muscle Fatigue
Interventions: RADIATION: Active laser|RADIATION: Sham laser|DIAGNOSTIC_TEST: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: CAR-T Cells in Treating Patients With Relapsed or Refractory NHL
Status: UNKNOWN
Conditions: Refractory Indolent Adult Non-Hodgkin Lymphoma
Interventions: DRUG: CD19 CAR-T|DRUG: CD22 CAR-T|DRUG: CD19+CD22 CAR-T|DRUG: Fludarabine|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Zirconia Vs Titanium Implants in Deficient Ridges
Status: UNKNOWN
Conditions: Alveolar Bone Loss|Periodontitis
Interventions: DEVICE: Zirconia implant|DEVICE: Titanium implant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PACIFIC: Providing Adults Collaborative Interventions For Ideal Changes
Status: COMPLETED
Conditions: Overweight|Obesity
Interventions: BEHAVIORAL: Regulation of Cues (ROC)|BEHAVIORAL: Behavioral Weight Loss (BWL)|BEHAVIORAL: BWL + ROC|BEHAVIORAL: Nutrition Education, Stress Management and Social Support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MESA Versus ESA in the Treatment of Early Stage NK/T-cell Lymphoma
Status: UNKNOWN
Conditions: Extranodal NK/T-cell Lymphoma, Nasal Type
Interventions: DRUG: Methotrexate|DRUG: Etoposide|DRUG: Dexamethasone|DRUG: Pegaspargase|RADIATION: Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Does Allopurinol Reduce Thickening of the Left Ventricle of the Heart in Patient With Treated Hypertension?
Status: COMPLETED
Conditions: Hypertension|Hypertrophy, Left Ventricular
Interventions: DRUG: Allopurinol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The New Strategy for Pharmacological Treatment in People With Schizophrenia
Status: UNKNOWN
Conditions: Schizophrenia
Interventions: DRUG: Rispridoen and Aripiprazole|DRUG: Risperidne|DRUG: Abilify
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Multifaceted Online Interventions to Increase Clinicians Searching of Current Best Evidence to Answer Clinical Questions
Status: COMPLETED
Conditions: Physicians Evidence Retrieval Skills
Interventions: BEHAVIORAL: Intervention A - Online Clinical Questions Recorder|BEHAVIORAL: Intervention B - Online Evidence Retrieval Coach|BEHAVIORAL: Intervention C - Online Audit and Feedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose:
Clinical trial: Trial of Inquiry Based Stress Reduction (IBSR) Program for BRCA1/2 Mutation Carriers
Status: COMPLETED
Conditions: Hereditary Breast and Ovarian Cancer Syndrome
Interventions: BEHAVIORAL: Inquiry Based Stress Reduction (IBSR) program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intensive Statin Therapy in PCI Patient With Acute Coronary Syndrome
Status: UNKNOWN
Conditions: Myocardial Infarction|Unstable Angina
Interventions: DRUG: Atorvastatin|DRUG: Statin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of CDP-choline in Patients With Methamphetamine Dependence
Status: COMPLETED
Conditions: Methamphetamine Dependence
Interventions: DIETARY_SUPPLEMENT: CDP-choline|DIETARY_SUPPLEMENT: Placebo (fructose)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, and Immunogenicity of Trivalent Coronavirus Vaccine Candidate VBI-2901a
Status: ACTIVE_NOT_RECRUITING
Conditions: COVID-19|Coronavirus Infections
Interventions: BIOLOGICAL: VBI-2901a
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Association of Pembrolizumab Infusion Time and Efficacy in Patients With Non-metastatic Triple-negative Breast Cancer (TNBC) Treated With Neoadjuvant Chemotherapy and Immunotherapy
Status: NOT_YET_RECRUITING
Conditions: Non-Metastatic Breast Carcinoma
Interventions: OTHER: No intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Treatment for Achilles Tendinopathy
Status: UNKNOWN
Conditions: Achilles Tendinopathy|Achilles Tendon Enthesopathy|Mid-Portion Achilles Tendinopathy|Insertional Achilles Tendinopathy|Non-Insertional Achilles Tendinopathy
Interventions: DRUG: 25% Dextrose and 1% Lidocaine|DRUG: Lidocaine|PROCEDURE: sclerotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pomalidomide or Lenalidomide and Dexamethasone in Treating Patients With Relapsed or Refractory Multiple Myeloma Previously Treated With Lenalidomide
Status: COMPLETED
Conditions: Recurrent Plasma Cell Myeloma|Refractory Plasma Cell Myeloma
Interventions: DRUG: Dexamethasone|DRUG: Lenalidomide|DRUG: Pomalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Pulmonary Vein Isolation to Pulmonary Vein Isolation + OPTIMA Ablation in Patients Undergoing Ablation for Atrial Fibrillation
Status: RECRUITING
Conditions: Atrial Fibrillation Chronic
Interventions: DEVICE: OPTIMA-guided catheter ablation|DEVICE: Standard PVI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Prospective Study of LessRay Enhanced Versus Standard Fluoroscopic Visualization in Surgical Placement of Spinal Cord Stimulator
Status: WITHDRAWN
Conditions: Fluoroscopy for Spine Surgery
Interventions: DEVICE: LessRay|DEVICE: Standard Fluoroscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Fluoroscopy-guided Versus Traditional Placement of Epidural Catheters
Status: COMPLETED
Conditions: Pain, Postoperative|Pain, Chronic
Interventions: DEVICE: Fluoroscopy|PROCEDURE: Traditional
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Bezlotoxumab (BEZLO) In Addition To Standard Of Care (SOC) Vancomycin For The Treatment of Multi-Recurrent Clostridium Difficile Infection
Status: COMPLETED
Conditions: Clostridium Difficile Infection Recurrence
Interventions: DRUG: bezlotoxumab|DRUG: Vancomycin Oral
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Omega-3 Dietary Supplements in Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia|Schizophreniform Disorder|Schizoaffective Disorder|Bipolar Disorder|Psychosis NOS
Interventions: DRUG: Risperidone|DRUG: Omega-3 capsules|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Safety and Tolerability of BI 894416 in Patients With Mild Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: BI 894416|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Duke Transplant University
Status: COMPLETED
Conditions: Kidney Transplant; Complications|Patient Empowerment|Medication Adherence|Patient Satisfaction
Interventions: BEHAVIORAL: SOC + Educational Videos Designed Especially for post-transplant patients
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Paclitaxel Micelles for Injection in Chinese Patients With Advanced Solid Tumors.
Status: RECRUITING
Conditions: Advanced Solid Tumors
Interventions: DRUG: Paclitaxel Micelles for Injection|DRUG: Paclitaxel injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized, Placebo-controlled, Double-blind Phase II Study Evaluating if Glucophage Can Avoid Liver Injury Due to Chemotherapy Associated Steatosis
Status: TERMINATED
Conditions: Colorectal Cancer|Steatohepatitis
Interventions: DRUG: Metformin/Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Stability of rTMS on Cognition and Brain Networks on Healthy Subjects.
Status: TERMINATED
Conditions: Healthy
Interventions: DEVICE: ineffective rTMS|DEVICE: active TBS|DEVICE: Sham TBS|DEVICE: fMRI|DEVICE: EEG|DEVICE: Effective rTMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: Maintaining Nonsmoking
Status: COMPLETED
Conditions: Nicotine Dependence
Interventions: DRUG: Varenicline|BEHAVIORAL: Initial Individual counseling|BEHAVIORAL: Check-ins with medical staff|BEHAVIORAL: Extended Individual Counseling - Health Model|BEHAVIORAL: Extended Individual Counseling - Relapse Prevention Model
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimizing Bilateral and Single-sided-deafness Cochlear Implants for Functioning in Complex Auditory Environments
Status: ENROLLING_BY_INVITATION
Conditions: Hearing Loss|Hearing Loss, Sensorineural|Cochlear Hearing Loss
Interventions: DIAGNOSTIC_TEST: Diagnostic tests of cochlear implant or acoustic hearing function|BEHAVIORAL: Targeted aural rehabilitation of the poorer performing ear
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Adherence to Care for Children With Congenital Zika Virus Infection in Puerto Rico
Status: COMPLETED
Conditions: Zika Virus Infection|Adherence, Patient
Interventions: BEHAVIORAL: Community Health Worker
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: PerQseal® Elite Venous Clinical Study (ELITE-Venous)
Status: NOT_YET_RECRUITING
Conditions: Large Hole Percutaneous Venous Closure
Interventions: DEVICE: PerQseal ELITE
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: COVID-19 PRIORITY (Pregnancy CoRonavIrus Outcomes RegIsTrY)
Status: COMPLETED
Conditions: Pregnancy|Coronavirus|COVID-19
Interventions: OTHER: Pregnant women under investigation for Coronavirus or diagnosed with COVID-19|OTHER: Postpartum women under investigation for Coronavirus or diagnosed with COVID-19
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Suture vs Staples for Skin Closure After Liver Resection
Status: COMPLETED
Conditions: Closure of the Skin After Liver Resection
Interventions: PROCEDURE: Suture Group|BIOLOGICAL: Staple Group (control)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Package of Mentholated Measures for the Relief of Thirst in the Anesthesia Recovery Room
Status: COMPLETED
Conditions: Thirst|Mouth Dryness|Irritation Lips
Interventions: OTHER: Mentholated lip moisturizer and ice popsicle|OTHER: Non-mentholated lip moisturizer and ice popsicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of mRNA-1010 Seasonal Influenza Vaccine in Adults 50 Years Old and Older
Status: COMPLETED
Conditions: Seasonal Influenza
Interventions: BIOLOGICAL: mRNA-1010|BIOLOGICAL: Licensed quadrivalent inactivated seasonal influenza vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Combination Chemotherapy Plus Radiation Therapy To Preserve the Larynx in Patients With Cancer of the Hypopharynx or Larynx
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: DRUG: cisplatin|DRUG: fluorouracil|PROCEDURE: conventional surgery|PROCEDURE: neoadjuvant therapy|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT