pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Prospective Randomised Phase II Trial Evaluating Adjuvant Pelvic Radiotherapy Using Either IMRT or 3-Dimensional Planning for Endometrial Cancer. ICORG 09-06
Status: TERMINATED
Conditions: Endometrial Cancer|Gastrointestinal Complications|Radiation Toxicity|Urinary Complications
Interventions: RADIATION: 45 Gy/25 fractions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Grass Sublingual Tablet in Children and Adolescents (P05239 AM3)(COMPLETED)
Status: COMPLETED
Conditions: Rhinoconjunctivitis|Rhinitis|Conjunctivitis|Allergy
Interventions: DRUG: Placebo|BIOLOGICAL: SCH 697243|DRUG: Loratadine Syrup 1 mg/mL Rescue Treatment|DRUG: Loratadine 10 mg Rescue Treatment|DRUG: Olopatadine 0.1% Rescue Treatment|DRUG: Mometasone furoate 50 mcg Rescue Treatment|DRUG: Albuterol 108 mcg Rescue Treatment|DRUG: Fluticasone 44 mcg Rescue Treatment|DRUG: Prednisone 5 mg Rescue Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Whole Almonds on Biomarkers of Cardiovascular Disease in Chinese Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: OTHER: Almond diet first, then NCEP Diet|OTHER: NCEP diet first, then Almond diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diet and Exercise Plus Metformin to Treat Frailty in Obese Seniors
Status: RECRUITING
Conditions: Frailty|Sarcopenic Obesity|Aging
Interventions: BEHAVIORAL: Lifestyle therapy|DRUG: Metformin Hydrochloride|DRUG: Placebo|BEHAVIORAL: Healthy Lifesylte
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Microbiota in Dietary Approach to Obesity
Status: COMPLETED
Conditions: Obesity
Interventions: OTHER: Standard hypocaloric die|OTHER: Intermittent fasting 16/8 (early fasting)|OTHER: Intermittent fasting 16/8 (late fasting)|OTHER: Alternate-day fasting|OTHER: Ketogenic diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Carbohydrate Oxidation in Elite Wheelchair Racers During Marathon Simulation
Status: UNKNOWN
Conditions: Dietary Carbohydrate|Para-Athletes
Interventions: OTHER: Carbohydrate dosing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of Pupilometer and Ultrasound of Optic Nerve Sheath Diameter in Estimating Intracranial Pressure (ICP)
Status: COMPLETED
Conditions: Intracranial Hemorrhages|Brain Injuries|Subarachnoid Hemorrhage|Ischemic Stroke|Stroke
Interventions: DEVICE: Ultrasound|DEVICE: Pupilometer
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Campylobacter Spp. Bone and Joint Infection: a Retrospective Cohort Study
Status: RECRUITING
Conditions: Campylobacter Infections
Interventions: OTHER: Management, progression and risk factors for failure of BJI caused by Campylobacter spp.|OTHER: Description of the evolution and risk factors for failure of osteoarticular infections caused by Campylobacter spp.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Lot Consistency Clinical Trial of Bivalent HPV Vaccine in 9 to 30 Years Old Healthy Females
Status: COMPLETED
Conditions: HPV Infection
Interventions: BIOLOGICAL: Recombinant Human Papillomavirus Bivalent (Types 16, 18) Vaccine (Pichia pastoris)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Lower Dose Chemotherapy Given More Frequent With Avastin to Treat Advanced Non-Squamous Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: Paclitaxel|DRUG: Gemcitabine|BIOLOGICAL: Avastin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of a Behavioral Tele-health Program on the Quality of Recovery for Patients Undergoing Total Joint Replacement Surgery
Status: UNKNOWN
Conditions: Opioid Dependence|Opioid Use|Pain, Joint
Interventions: BEHAVIORAL: Lucid Lane Therapy Program|BEHAVIORAL: Surgical Preparedness Course
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Vitamin D as a Therapeutic Adjunct in the Stimulant Treatment of ADHD
Status: COMPLETED
Conditions: ADHD
Interventions: PROCEDURE: Magnetic Resonance Imaging (MRI)|DRUG: PHNO|DIETARY_SUPPLEMENT: calcitriol|DRUG: Placebo oral capsule|PROCEDURE: high-resolution research tomography|DRUG: Dextro Amphetamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Inhaled Nitric Oxide in Prevention/Treatment of Ischemia-Reperfusion Lung Injury Related to Lung Transplantation
Status: TERMINATED
Conditions: Ischemia-Reperfusion Injury
Interventions: DRUG: nitric oxide for inhalation|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Mechanisms of Endothelial Cell Dysfunction in Sleep Apnea
Status: COMPLETED
Conditions: Obstructive Sleep Apnea|Hypoxemia
Interventions: DEVICE: Continuous Positive Airway Pressure (CPAP)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Three Different Post-Feeding Positions on Vital Signs and Comfort Levels in Preterm Infants
Status: COMPLETED
Conditions: Premature
Interventions: OTHER: The application of right lateral, supine, and prone positions to preterm infants after feeding
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of Increasing Strengths, Safety and Efficacy of Two Formulas of LEO 43204 on the Face or the Chest in Patients With Actinic Keratosis
Status: COMPLETED
Conditions: Actinic Keratosis
Interventions: DRUG: LEO 43204 Formulation 1|DRUG: LEO 43204 Formulation 2|DRUG: LEO 43204 Formulation 1 Dose X|DRUG: LEO 43204 Formulation 1 Dose Y|DRUG: LEO 43204 Formulation 2 Dose XX|DRUG: LEO 43204 Formulation 2 Dose YY|DRUG: Placebo Formulation 1|DRUG: Placebo Formulation 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Non-grafted Maxillary Sinus Floor Elevation With Simultaneous Implant Placement Using Different Implant Lengths
Status: UNKNOWN
Conditions: Maxillary Sinus Lift
Interventions: PROCEDURE: maxillary sinus lift
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety of Clonidine in Infants With Hypoxic Ischemic Encephalopathy During Therapeutic Hypothermia
Status: COMPLETED
Conditions: Encephalopathy, Hypoxic-Ischemic
Interventions: DRUG: Clonidine (Duraclon®)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SMS Reminders and Treatment Compliance and Efficacy in Patients With FGIDs
Status: UNKNOWN
Conditions: Functional Gastrointestinal Disorders|Patient Compliance
Interventions: BEHAVIORAL: SMS follow-up
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Ultrasound Guided Ozone, Platelet-Rich Plasma or Steroid Injection in the Treatment of Sacroiliitis; a Randomized Double Blinded Controlled Study
Status: RECRUITING
Conditions: the Efficacy of Ultrasound Guided Sacroiliac Injection of Ozone, Platelet Rich Plasma (PRP) or Steroid for Treatment of Sacroiliitis
Interventions: PROCEDURE: ultrasound guided Ozone, platelet-rich plasma or steroid injection in the treatment of sacroiliitis|DRUG: methylprednisolone acetate and lidocaine|DRUG: PRP and lidocaine|DRUG: medical ozone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Cross Over Study to Compare the Effect of Combined Treatment With QAV680 and Cetirizine
Status: COMPLETED
Conditions: Allergic Rhinitis
Interventions: DRUG: QAV680 + Cetirizine Placebo|DRUG: QAV680 + Cetirizine|DRUG: Cetirizine + QAV680 Placebo|DRUG: QAV680 Placebo + Cetirizine Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Preoperative Immunotherapy (Pembrolizumab) for Patients With Colorectal Cancer and Resectable Hepatic Metastases
Status: RECRUITING
Conditions: Metastatic Malignant Neoplasm in the Liver|Stage IV Colorectal Cancer AJCC v8|Stage IVA Colorectal Cancer AJCC v8|Stage IVB Colorectal Cancer AJCC v8|Stage IVC Colorectal Cancer AJCC v8
Interventions: PROCEDURE: Hepatectomy|BIOLOGICAL: Pembrolizumab|DRUG: Vactosertib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Morbidity After Laparoscopic Cholecystectomy for Acutely Inflamed Gall Bladder With and Without Drain
Status: COMPLETED
Conditions: Acute Cholecystitis|Pain|Morbidity, Multiple|Surgery|Drain Site Complication
Interventions: OTHER: Suction drain
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Impact of Multiple Doses of BAY63-2521 on Safety, Tolerability, Pharmacokinetics and Pharmacodynamics in Patients With Interstitial Lung Disease (ILD) Associated Pulmonary Hypertension (PH)
Status: ACTIVE_NOT_RECRUITING
Conditions: Hypertension, Pulmonary
Interventions: DRUG: Riociguat (Adempas, BAY63-2521)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Thoracolumbar Interfascial Plane Block With Erector Spinae Plane Block
Status: COMPLETED
Conditions: Spinal Surgery|Quality of Recovery|Postoperative Analgesia|Postoperative Complications
Interventions: PROCEDURE: TLIPB|PROCEDURE: ESPB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of PEGASYS (Peginterferon Alfa-2a (40KD)) in Patients With Lamivudine Resistant HBeAg-Negative Chronic Hepatitis B.
Status: TERMINATED
Conditions: Hepatitis B, Chronic
Interventions: DRUG: peginterferon alfa-2a (40KD) [PEGASYS]
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Effectiveness of Tenofovir Disoproxil Fumarate (Tenofovir DF) Plus Other Anti-HIV Drugs in HIV-Infected Patients
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Tenofovir disoproxil fumarate
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Psoriatic Arthritis Dose Ranging Study for BMS-945429 in Subjects Who Are Not Responding to NSAIDs or Non-biologic Disease Modifying Anti-rheumatic Drugs (DMARDs) Therapy
Status: COMPLETED
Conditions: Arthritis, Psoriatic
Interventions: BIOLOGICAL: Placebo matching BMS-945429|BIOLOGICAL: BMS-945429|BIOLOGICAL: BMS-945429|BIOLOGICAL: BMS-945429
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Vitamin K2 in the Treatment of Nocturnal Leg Cramps in Older Population
Status: ENROLLING_BY_INVITATION
Conditions: Nocturnal Leg Cramps
Interventions: DRUG: Vitamin K2|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Energy Transfer Therapy in Treatment of Medial Gastrocnemius
Status: COMPLETED
Conditions: Strain of Gastrocnemius Muscle (Diagnosis)|Diathermy Plate Burn|Thermography|Sports Physical Therapy
Interventions: PROCEDURE: TECAR Therapy|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: To Explore the Safety and Efficacy of Intravenous Infusion of Different Doses of Lidocaine in Patients
Status: UNKNOWN
Conditions: Liver Cancer
Interventions: DRUG: Lidocaine Hydrochloride, Injectable
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Barzolvolimab in Patients With Prurigo Nodularis
Status: RECRUITING
Conditions: Prurigo Nodularis
Interventions: BIOLOGICAL: barzolvolimab|OTHER: Matching Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Extension Study To Evaluate Safety And Tolerability Of 24-Hour Daily Exposure Of Continuous Subcutaneous Infusion of ABBV-951 In Adult Participants With Parkinson's Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Parkinson's Disease (PD)
Interventions: DRUG: ABBV-951
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High Intensity Multi-Modal Exercise Training in Postmenopausal Women
Status: COMPLETED
Conditions: Postmenopausal Osteoporosis|Postmenopausal Osteopenia
Interventions: OTHER: High Intensity Exercises|OTHER: General Exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Physiotherapy in Order to Improve Walking Capacity and Participation in Chronic Stroke Subjects
Status: COMPLETED
Conditions: Stroke
Interventions: OTHER: Cardiovascular and task-oriented training|OTHER: Upper limb strength training program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sonography-Guided Volumetric Rejuvenation on Dorsal Hands
Status: RECRUITING
Conditions: Ultrasound|Injection Site
Interventions: PROCEDURE: Volumetric rejuvenation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pre-pregnancy Lifestyle Intervention to Prevent the Recurrence of Gestational Diabetes in Overweight and Obese Women
Status: COMPLETED
Conditions: Gestational Diabetes Mellitus
Interventions: BEHAVIORAL: Lifestyle intervention|OTHER: Health Promotion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Designer Functional Foods on Parameters of Metabolic and Vascular in Prediabetes
Status: WITHDRAWN
Conditions: Pre-Diabetes
Interventions: DIETARY_SUPPLEMENT: Functional Ingredient Group|DIETARY_SUPPLEMENT: Control Ingredient Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Study Evaluating the Safety and Efficacy of Eribulin Mesilate in Combination With Irinotecan Hydrochloride in Children With Refractory or Recurrent Solid Tumors
Status: COMPLETED
Conditions: Refractory or Recurrent Solid Tumors|Rhabdomyosarcoma|Non-Rhabdomyosarcoma Soft Tissue Sarcoma|Ewing Sarcoma
Interventions: DRUG: Eribulin mesilate|DRUG: Irinotecan hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Assess the Safety and Efficacy of Ciclesonide Applied as a Nasal Spray in the Treatment of Perennial Allergic Rhinitis (BY9010/M1-402)
Status: COMPLETED
Conditions: Rhinitis, Allergic, Perennial
Interventions: DRUG: Ciclesonide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Coenzyme Q10 on Hearing and Tinnitus Characteristics of Chronic Tinnitus Patients
Status: UNKNOWN
Conditions: Tinnitus
Interventions: DIETARY_SUPPLEMENT: Q10|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Glycemic Excursions in Patients With Type 1 Diabetes Mellitus Using Closed-loop Systems
Status: RECRUITING
Conditions: Type 1 Diabetes Mellitus|Type 1 Diabetes Mellitus With Hypoglycemia|Drive
Interventions: DEVICE: MiniMed 780 G
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety of M281 in Adults With Warm Autoimmune Hemolytic Anemia
Status: RECRUITING
Conditions: Warm Autoimmune Hemolytic Anemia
Interventions: DRUG: M281|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Moderate Physical Activity on Early Symptoms of Peripheral Diabetic Neuropathy in Type-II Diabetes: A Randomized Clinical Trial
Status: COMPLETED
Conditions: Peripheral Diabetic Neuropathy
Interventions: OTHER: Moderate Physical Activity for Peripheral Diabetic Neuropathy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Millimeter Wave Emission Bracelet for Improving Parkinson's Disease Symptoms
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: DEVICE: Evaluation of a millimeter wave emission bracelet for improving Parkinson's disease symptoms
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: NCPAP + Heliox as a Treatment for Infant Respiratory Distress Syndrome (RDS)
Status: COMPLETED
Conditions: Respiratory Distress Syndrome|Bronchopulmonary Dysplasia
Interventions: OTHER: NCPAP + standard air|OTHER: NCPAP + Heliox
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dynamic Humeral Centering Exercises in Subacromial Pain Syndrome
Status: RECRUITING
Conditions: Shoulder Pain|Shoulder Impingement Syndrome
Interventions: BEHAVIORAL: Conventional physical therapy|BEHAVIORAL: Conventional physical therapy + Dynamic Humeral Centering exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Examine the Effects of Maintaining Body Core Temperature During CABGs
Status: UNKNOWN
Conditions: Anesthesia|Hypothermia|Coronary Artery Bypass Grafting
Interventions: DEVICE: Allon Thermowrap. MTRE Advanced Technologies Ltd.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial of mFOLFIRI With MEK162 in Patients With Advanced RAS (HRAS, NRAS, or KRAS) Positive Metastatic Colorectal Cancers
Status: COMPLETED
Conditions: Advanced KRAS Positive Metastatic Colorectal Cancer
Interventions: DRUG: MEK162 and mFOLFIRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Characterization of Heart Failure With Preserved Ejection Fraction
Status: RECRUITING
Conditions: Heart Failure, Preserved Ejection Fraction|Cardiac Fibrosis|Biomarkers|Magnetic Resonance Imaging
Interventions: DIAGNOSTIC_TEST: cMR|BIOLOGICAL: biomarker
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Glofitamab With Obinutuzumab, Venetoclax, and Lenalidomide for the Treatment of Patients With Newly Diagnosed High Risk Mantle Cell Lymphoma
Status: RECRUITING
Conditions: Blastoid Variant Mantle Cell Lymphoma|Mantle Cell Lymphoma|Pleomorphic Variant Mantle Cell Lymphoma
Interventions: PROCEDURE: Biopsy|PROCEDURE: Biospecimen Collection|PROCEDURE: Bone Marrow Biopsy|PROCEDURE: Computed Tomography|BIOLOGICAL: Glofitamab|DRUG: Lenalidomide|BIOLOGICAL: Obinutuzumab|PROCEDURE: Positron Emission Tomography|DRUG: Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Foot and Ankle Ability Measure (FAAM) is Translated From English to Turkish and Assess the Validity and Reliability in Athletic Population Who Have Foot and Ankle Disorders.
Status: COMPLETED
Conditions: Ankle; Injury, Superficial, Multiple (With Foot)
Interventions: OTHER: Foot and Ankle Ability Measure Turkish version (FAAM-T) questionnaire
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Cardiac Progenitor Cell Infusion to Treat Univentricular Heart Disease (PERSEUS)
Status: COMPLETED
Conditions: Hypoplastic Left Heart Syndrome|Single Right Ventricle|Single Left Ventricle
Interventions: GENETIC: Cardiac progenitor cell infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Biomarkers of Liver Pathology in Patients With Presumed Non-Alcoholic Steatohepatitis Following Bariatric Surgery
Status: COMPLETED
Conditions: NASH - Nonalcoholic Steatohepatitis; NAFLD - Nonalcoholic Fatty Liver Disease
Interventions: PROCEDURE: Bariatric surgery|DEVICE: HepQuant SHUNT Dual Cholate Liver Diagnostic Kit
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Digital Motivational Behavioral Economic Intervention to Reduce Risky Drinking Among Community-Dwelling Emerging Adults
Status: RECRUITING
Conditions: Alcohol Drinking
Interventions: BEHAVIORAL: Motivational Behavioral Economic Alcohol Intervention|BEHAVIORAL: Health Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Safety and Tolerability of VS-01 in Adult Patients With Acute-on-Chronic Liver Failure and Ascites (UNVEIL-IT)®
Status: RECRUITING
Conditions: Acute-On-Chronic Liver Failure|Ascites
Interventions: DRUG: VS-01 on top of SOC|OTHER: SOC (Control Group)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Imiquimod and Laser Therapy With or Without a Green Dye in Treating Patients With Stage III or Stage IV Melanoma That Has Spread to Other Parts of the Skin
Status: COMPLETED
Conditions: Melanoma (Skin)|Metastatic Cancer
Interventions: DRUG: imiquimod|DRUG: indocyanine green solution|OTHER: flow cytometry|OTHER: immunologic technique|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gene Expression Profiling in Patients With Invasive Bladder Cancer Receiving Methotrexate, Vinblastine, Doxorubicin, and Cisplatin
Status: TERMINATED
Conditions: Bladder Cancer
Interventions: DRUG: cisplatin|DRUG: doxorubicin hydrochloride|DRUG: methotrexate|DRUG: vinblastine|GENETIC: gene expression profiling|PROCEDURE: neoadjuvant therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radiotherapy + Metronidazole vs Radiotherapy Alone In Improving Treatment Outcomes in Advanced Cervical Cancer in Uganda
Status: COMPLETED
Conditions: Cervix Carcinoma
Interventions: DRUG: Radiotherapy plus metronidazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: This Study Intends to Describe the Characteristics of Patients Given the Pfizer-BioNTech Bivalent mRNA COVID-19 Vaccine and Any Commercially Available Influenza Vaccines at the Same Time Versus at Different Times.
Status: COMPLETED
Conditions: Influenza, Human|COVID-19
Interventions: BIOLOGICAL: Comirnaty|BIOLOGICAL: Quadrivalent Influenza Vaccine
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase 1/2 Study of Oral SB1518 in Subjects With Chronic Idiopathic Myelofibrosis
Status: COMPLETED
Conditions: Myelofibrosis|Myeloproliferative Disorders|Polycythemia Vera|Essential Thrombocythemia
Interventions: DRUG: SB1518
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cardiopulmonary Bypass-Induced Lymphocytopenia and the Potential Effects of Protease Inhibitor
Status: TERMINATED
Conditions: Cardiopulmonary Bypass
Interventions: DRUG: Nelfinavir/placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Oro-gastro-intestinal Digestion of Emulsified Fat
Status: COMPLETED
Conditions: Obesity
Interventions: DIETARY_SUPPLEMENT: administration of fat (sunflower oil), emulsified|PROCEDURE: Insertion of nasoduodenal tube
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Omega-3 Fatty Acids and Exercise on Mobility and Cognition in Older Women
Status: COMPLETED
Conditions: Aging|Cognitive Decline
Interventions: DIETARY_SUPPLEMENT: Efamol Active 50+|BEHAVIORAL: Aerobic exercise|DIETARY_SUPPLEMENT: Placebo multinutrient
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study to Explore the Optimal Dosage/Administration in Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: PM012|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Epidural Analgesia on Electrophysiological Function
Status: COMPLETED
Conditions: Prolonged Labor|Healthy|Pelvic Floor Disorders
Interventions: DRUG: CSEA (ropivocaine and sufentanil)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Methotrexate in Ankylosing Spondylitis (MTX in AS)
Status: UNKNOWN
Conditions: Ankylosing Spondylitis
Interventions: DRUG: Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: ECT
Clinical trial: Tacrolimus Monotherapy for Idiopathic Membranous Nephropathy
Status: UNKNOWN
Conditions: Tacrolimus|Idiopathic Membranous Nephropathy|Clinical Trial
Interventions: DRUG: Tacrolimus|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Adebrelimab Plus Irinotecan Liposome (II) With or Without Famitinib in ES-SCLC Pre-treated With Immunotherapy
Status: NOT_YET_RECRUITING
Conditions: Extensive-stage Small-cell Lung Cancer
Interventions: DRUG: Adebrelimab, Irinotecan Liposome (II)|DRUG: Adebrelimab, Irinotecan Liposome (II), Famitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Different Remineralizing Agents on White Spot Lesions and Dental Plaque During Orthodontic Retention
Status: UNKNOWN
Conditions: Orthodontic Appliance Complication
Interventions: COMBINATION_PRODUCT: Fluoridated toothpaste|COMBINATION_PRODUCT: fluoride varnish (5% sodium fluoride)|COMBINATION_PRODUCT: CPP-ACP plus crème group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exercise Effects on Brain Health and Learning From Minutes to Months
Status: COMPLETED
Conditions: Sedentary Lifestyle
Interventions: BEHAVIORAL: Cardiorespiratory fitness training|BEHAVIORAL: Functional fitness training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Relative Bioavailability Study to Assess an LC350189 Tablet Compared to an LC350189 Capsule in Healthy Adults
Status: COMPLETED
Conditions: Gout|Hyperuricemia
Interventions: DRUG: LC350189 Tablet|DRUG: LC350189 Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PAP Systems Internal Clinical Studies (ICS)
Status: NOT_YET_RECRUITING
Conditions: Obstructive Sleep Apnea
Interventions: DEVICE: PAP System A (with Amalfi) then PAP System B (with CLA11)|DEVICE: PAP System B (with CLA11) then PAP System A (with Amalfi)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Use of Autologous Stem/Stromal Cells In Chronic Lung Disorders: Obstructive (COPD) & Restrictive (RLD)
Status: SUSPENDED
Conditions: COPD|Respiratory Insufficiency
Interventions: PROCEDURE: Lipoaspiration|PROCEDURE: AD-cSVF|PROCEDURE: Normal Saline IV
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Lip Injections With Emervel Lips and Juvederm Ultra Smile
Status: COMPLETED
Conditions: Local Tolerability After Lip Filler Injections
Interventions: DEVICE: Emervel Lips|DEVICE: Juvederm Ultra Smile
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cellular Adoptive Immunotherapy in Treating Patients With Relapsed or Refractory Follicular Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: BIOLOGICAL: aldesleukin|BIOLOGICAL: rituximab|BIOLOGICAL: therapeutic autologous lymphocytes|DRUG: fludarabine phosphate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Relative Bioavailability of Two Different Capsule Formulations of Sitravatinib in Healthy Adults
Status: COMPLETED
Conditions: Tumor
Interventions: DRUG: Sitravatinib|DRUG: Sitravatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Use of a Restrictive Fluid Regimen With Hypertonic Saline for Patients Undergoing Pancreaticoduodenectomy
Status: UNKNOWN
Conditions: Pancreaticoduodenectomy
Interventions: DRUG: 3% NaCl Solution|DRUG: Lactated Ringers Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Inspiratory Muscle Training in Chronic Venous Diseases
Status: NOT_YET_RECRUITING
Conditions: Chronic Venous Insufficiency
Interventions: OTHER: Inspiratuar Muscle Training Group|OTHER: Thoracic Expansion Exercise Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: P4 Approach in Diabetes Type 2
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: BEHAVIORAL: Intervention A: Diet|BEHAVIORAL: Intervention B: Exercise|BEHAVIORAL: Intervention C: Diet and Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Intraperitoneal Paclitaxel-loaded TPM for Treatment of Peritoneal Carcinomatosis
Status: RECRUITING
Conditions: Peritoneal Carcinomatosis
Interventions: DRUG: Paclitaxel-loaded tumor penetrating microparticles
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A First-in-Human Study of JNJ-28431754 in Healthy Male Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: JNJ-28431754/ Placebo|DRUG: JNJ-28431754
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of DEXYCU® for the Treatment of Ocular Pain Associated With Cataract Surgery
Status: UNKNOWN
Conditions: Cataract
Interventions: DRUG: Dexycu|OTHER: Placebo/Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Combined Immunotherapy With Trastuzumab and Cetuximab in Patients With Metastatic Breast Cancer
Status: UNKNOWN
Conditions: Metastatic Breast Cancer
Interventions: DRUG: Cetuximab|DRUG: Trastuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Registration Trial of the Intracranial Visualized Stent for the Wide-necked Intracranial Aneurysms:REBRIDGE
Status: RECRUITING
Conditions: Brain Diseases|Aneurysm|Intracranial Aneurysm
Interventions: DEVICE: Intracranial stent for wide-necked aneurysms
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Almonertinib Combined With Cerebral Radiation Treat Brain Metastases From EGFR Positive NSCLC
Status: UNKNOWN
Conditions: Non-Small Cell Lung Cancer (NSCLC)
Interventions: DRUG: Almonertinib|RADIATION: Stereotactic Radiotherapy(SRT) or Stereotactic Radiosurgery(SRS) or Whole-Brain Radiotherapy(WBRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: T Cell Receptor-transduced T Cells Targeting NY-ESO-1 for Treatment of Patients With NY-ESO-1- Expressing Malignancies
Status: UNKNOWN
Conditions: Bladder Carcinoma|Breast Cancer|Esophagus Carcinoma|Lung Cancer|Melanoma|Multiple Myeloma|Neuroblastoma|Ovarian Cancer|Synovial Sarcoma|Other Metastatic Solid Cancers
Interventions: DRUG: Cyclophosphamide|DRUG: Fludarabine|BIOLOGICAL: Anti-NY ESO-1 TCR-transduced T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Perception and Attitude Toward Estrogen Therapy Among Surgically Menopausal Women
Status: UNKNOWN
Conditions: Menopause, Premature|Hysterectomy|Ovariectomy|Estrogen Replacement Therapy|Attitude|Perception
Interventions: PROCEDURE: Hysterectomy and Bilateral salpingo-oophorectomy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Prophylactic Antibiotics for Manual Removal of Retained Placenta in Vaginal Birth: a Randomized Controlled Trial
Status: UNKNOWN
Conditions: Endometritis
Interventions: DRUG: Antibiotic prophylaxis|DRUG: Ampicillin|DRUG: Gentamycin|DRUG: Clindamycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Different Ways for Using Lidocaine During FB
Status: NOT_YET_RECRUITING
Conditions: Lidocaine Spray|Nebulized Lidocaine|Lung Diseases|Lung Cancer
Interventions: PROCEDURE: Nebulized lidocaine|PROCEDURE: Lidocaine spray|PROCEDURE: Combination of nebulized lidocaine and lidocaine spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Spider Versus Emboshield Distal Protection on Cerebral Microembolization During Vulnerable Plaque in Carotid Artery Stenting
Status: NOT_YET_RECRUITING
Conditions: Stroke|Carotid Stenosis|Carotid Artery Stent
Interventions: DEVICE: Emboshield|DEVICE: Spider
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Betaferon/ Betaseron (Interferon Beta-1b) in Patients With Chronic Viral Cardiomyopathy
Status: COMPLETED
Conditions: Cardiomyopathies|Heart Diseases
Interventions: DRUG: Interferon beta-1b (Betaferon/Betaseron, BAY86-5046)|DRUG: Interferon beta-1b (Betaferon/Betaseron, BAY86-5046)|DRUG: Placebo|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Metformin on Fecundability in an ART(Assisted Reproductive Technology) Setting - the Correlation to Uterine Flows
Status: UNKNOWN
Conditions: Infertility Female
Interventions: DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Chronic Hepatitis C With PEG Interferon alfa2a and Ribavirin in HIV-Infected Patients
Status: COMPLETED
Conditions: HIV Infections|Hepatitis C, Chronic|Treatment Failure
Interventions: DRUG: Peginterferon alfa2a|DRUG: Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Glasdegib (PF-04449913) With Temozolomide Newly Diagnosed Glioblastoma
Status: COMPLETED
Conditions: Glioblastoma
Interventions: DRUG: PF-04449913|DRUG: Temozolomide Oral Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Molecular Breast Imaging Guidance for Breast Biopsy for Patients With Breast Abnormalities
Status: RECRUITING
Conditions: Breast Neoplasm
Interventions: PROCEDURE: Biopsy of Breast|OTHER: Medical Device Usage and Evaluation|RADIATION: Scintimammography|OTHER: Technetium Tc-99m Sestamibi
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effectiveness of Transcranial Direct Current in Patients With Persistent COVID-19 With Headaches and Chronic Pain.
Status: RECRUITING
Conditions: COVID-19|Long COVID|Long Covid19|SARS CoV 2 Infection|Persistent COVID-19|Migraine Disorders|Headaches Chronic|Cluster Headache|Arthralgia|Myalgia|Chronic Pain|Post-COVID-19 Syndrome|Post COVID-19 Condition
Interventions: DEVICE: Transcranial Direct Current Therapy (tDCS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anti-Argonaute Antibodies for the Diagnosis of Sensory Neuronopathies
Status: COMPLETED
Conditions: Autoimmune Diseases
Interventions: DIAGNOSTIC_TEST: Diagnosis of sensitive neuronopathy - phase 1|DIAGNOSTIC_TEST: Diagnosis of sensitive neuronopathy - phase 2|OTHER: Comparison with Chi2 method|OTHER: Comparison of data with parametric Test (T-test)|OTHER: Comparison of data with non-parametric test (ANNOVA)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Collecting and Storing Blood and Brain Tumor Tissue Samples From Children With Brain Tumors
Status: COMPLETED
Conditions: Childhood Atypical Teratoid/Rhabdoid Tumor|Childhood Central Nervous System Germ Cell Tumor|Childhood Cerebral Anaplastic Astrocytoma|Childhood Cerebral Astrocytoma|Childhood Choroid Plexus Neoplasm|Childhood Craniopharyngioma|Childhood Grade I Meningioma|Childhood Grade II Meningioma|Childhood Grade III Meningioma|Childhood Infratentorial Ependymoma|Childhood Oligodendroglioma|Childhood Supratentorial Ependymoma|Ependymoma|Newly Diagnosed Childhood Ependymoma|Recurrent Childhood Cerebellar Astrocytoma|Recurrent Childhood Cerebral Astrocytoma|Recurrent Childhood Ependymoma|Recurrent Childhood Medulloblastoma|Recurrent Childhood Supratentorial Embryonal Tumor, Not Otherwise Specified|Recurrent Childhood Visual Pathway Glioma
Interventions: OTHER: Cytology Specimen Collection Procedure
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Anlotinib Combined With Osimertinib as Second-line Treatment in Stage IIIb-IV NSCLC With Confirmed EGFRm and T790M
Status: UNKNOWN
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: Anlotinib Combined With Osimertinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Long-term Follow-up Study to Evaluate the Safety and Efficacy of RGX-501
Status: ACTIVE_NOT_RECRUITING
Conditions: Homozygous Familial Hypercholesterolemia (HoFH)
Interventions: DRUG: Single intravenous (IV) dose of human Low Density Lipoprotein Receptor (LDLR) Gene Therapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Transvaginal Cholecystectomy Versus Laparoscopic Cholecystectomy in Patients With Biliary Colic
Status: COMPLETED
Conditions: Biliary Colic
Interventions: PROCEDURE: transvaginal cholecystectomy|PROCEDURE: laparoscopic cholecystectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Metronidazole and Doxycycline to Treat Oral Lichen Planus and to Compare Their Efficacy With Each Other
Status: COMPLETED
Conditions: Oral Lichen Planus
Interventions: DRUG: metronidazole,doxycycline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Effect of CBD on the Brain
Status: NOT_YET_RECRUITING
Conditions: Fragile X Syndrome
Interventions: DRUG: CBD Oral Solution (eCBD system Target)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Active Video Games on Chinese Overweight and Obese College Students' Physical and Mental Health
Status: RECRUITING
Conditions: Physical Inactivity|Mental Health Issue|Body Weight Changes
Interventions: BEHAVIORAL: Active video games intervention（1-6weeks）|BEHAVIORAL: Active video games intervention（7-12weeks）
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect of Curcumin on the Development of Prednisolone-induced Hepatic Insulin Resistance
Status: TERMINATED
Conditions: Insulin Resistance|Non-Alcoholic Fatty Liver Disease
Interventions: DRUG: Curcumin Liposome|DRUG: Prednisolone|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Identifying Best Approach in Improving Quality of Life and Survival After a Donor Stem Cell Transplant in Older, Medically Infirm, or Frail Patients With Blood Diseases
Status: RECRUITING
Conditions: Hematopoietic and Lymphoid Cell Neoplasm|Non-Neoplastic Hematologic and Lymphocytic Disorder
Interventions: OTHER: Supportive Palliative Care|OTHER: Clinical Management|OTHER: Best Practice|PROCEDURE: Allogeneic Hematopoietic Stem Cell Transplantation|OTHER: Questionnaire Administration|OTHER: Quality-of-Life Assessment|OTHER: Survey Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Trigona Honey and Intestinal Microbiota Among Obese People
Status: UNKNOWN
Conditions: Obesity
Interventions: DIETARY_SUPPLEMENT: Trigona honey|DIETARY_SUPPLEMENT: control
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of ARO-MUC5AC in Healthy Subjects and Patients With Muco-Obstructive Lung Disease
Status: RECRUITING
Conditions: Asthma|Chronic Obstructive Pulmonary Disease
Interventions: DRUG: ARO-MUC5AC|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The CLARICOR Trial: Effect of Clarithromycin on Mortality and Morbidity in Patients With Ischemic Heart Disease
Status: COMPLETED
Conditions: Heart Disease|Cardiovascular Disease
Interventions: DRUG: clarithromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Double-blinded,Double-dummy Clinical Trial of Chinese Herbal Medicine (MaZiRenWan) for Functional Constipation
Status: COMPLETED
Conditions: Functional Constipation|Gastrointestinal Disorders
Interventions: DRUG: MZRW|DRUG: Senna|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Isometric Conditioning Activity on Subsequent Jumping Performance in Volleyball Players
Status: COMPLETED
Conditions: Resistance Training
Interventions: OTHER: Dominant Limb Overcoming Isometric Conditioning Activity|OTHER: Non-dominant Limb Overcoming Isometric Conditioning Activity
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT