pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Chronic Inflammatory Disease, Lifestyle and Risk of Disease
Status: UNKNOWN
Conditions: Autoimmune Diseases|Inflammatory Bowel Diseases|Crohn Disease (CD)|Ulcerative Colitis (UC)|Arthritis, Rheumatoid (RA)|Spondylarthropathies|Arthritis, Psoriatic (PsA)|Psoriasis (PsO)|Multiple Sclerosis (MS)
Interventions: OTHER: Intake of red and processed meat and fibres|OTHER: Lifestyle factors independently or combined
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of DOXIL/CAELYX (Pegylated Liposomal Doxorubicin) and VELCADE (Bortezomib) or VELCADE Monotherapy for the Treatment of Relapsed Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Bortezomib (VELCADE)|DRUG: Bortezomib (VELCADE)|DRUG: Doxorubicin hydrochloride (DOXIL/CAELYX)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect Of Paricalcitol (Zemplar) On Endothelial Function And Inflammation In Type 2 Diabetes And Chronic Kidney Disease
Status: UNKNOWN
Conditions: Type 2 Diabetes|Chronic Kidney Disease
Interventions: DRUG: Zemplar|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Feasibility of Home Based Transcutaneous Spinal Cord Stimulation for Persons With SCI
Status: NOT_YET_RECRUITING
Conditions: Tetraplegia
Interventions: BEHAVIORAL: transcutaneous Spinal Cord Stimulation (tSCS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Dose Ranging Phase IIa Study of 6 Hour Intravenous Dosages of CXL-1427 in Patients Hospitalized With Heart Failure
Status: COMPLETED
Conditions: Heart Failure|Decompensated Heart Failure|Acute Heart Failure
Interventions: DRUG: CXL-1427|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Theta Burst Stimulation in Binge Eating Disorder: A Single Session RCT
Status: WITHDRAWN
Conditions: Binge-Eating Disorder
Interventions: DEVICE: Intermittent Theta Burst Stimulation|DEVICE: Sham Intermittent Theta Burst Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Nedaplatin in Treatment for Nasopharyngeal Carcinoma
Status: COMPLETED
Conditions: Nasopharyngeal Carcinoma
Interventions: DRUG: Docetaxel, nedaplatin, fluorouracil|RADIATION: IMRT|DRUG: Nedaplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RCT of Cognitive Therapy, Paroxetine, Combined CT and Paroxetine and Placebo
Status: COMPLETED
Conditions: Phobic Disorders
Interventions: DRUG: Seroxat, Cognitive therapy, Seroxat+ cognitive therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Adebrelimab Plus Chemotherapy, Bevacizumab and Fluzoparib in Platinum-Sensitive Relapsed Ovarian Cancer
Status: NOT_YET_RECRUITING
Conditions: Platinum-sensitive Relapsed Ovarian Cancer
Interventions: DRUG: Adebrelimab, paclitaxel, carboplatin, bevacizumab, fluzoparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy of MuGard for the Amelioration of Oral Mucositis in Head and Neck Cancer Patients
Status: COMPLETED
Conditions: Oral Mucositis
Interventions: DEVICE: MuGard|DEVICE: Control Rinse
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Influence of Different At-home Exercise Strategies on 24h Glycemic Control
Status: COMPLETED
Conditions: Metabolic Disturbance
Interventions: BEHAVIORAL: Bodyweight interval exercise|BEHAVIORAL: Walking
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hyper-Spectral Endoscopy for Detection of Early Neoplasia in Barrett's Oesophagus
Status: NOT_YET_RECRUITING
Conditions: Endoscopy
Interventions: DEVICE: Hyper-Spectral Endoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation of the Non-inferiority of Cefoxitin Versus Imipenem/Cilastatin in the Treatment of Urinary Tract Infections Caused by ESBL-producing Escherichia Coli
Status: TERMINATED
Conditions: Urinary Tract Infections
Interventions: DRUG: Cefoxitin|DRUG: imipenem
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Invasive Group B Streptococcus Disease Burden and Its Antimicrobial Resistance in Malaysia Among Non-pregnant Adults.
Status: RECRUITING
Conditions: Invasive Infection|Diabetic Foot|Immunocompromised Patients|Group B Streptococcal Infections
Interventions: OTHER: No Intervention in This study
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Interferon Beta in Treating Patients With Metastatic Cutaneous Melanoma or Ocular Melanoma
Status: COMPLETED
Conditions: Stage IV Melanoma|Recurrent Melanoma
Interventions: BIOLOGICAL: recombinant interferon beta
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Induction of Regulatory t Cells by Low Dose il2 in Autoimmune and Inflammatory Diseases
Status: COMPLETED
Conditions: Rheumatoid Arthritis|Ankylosing Spondylitis|Systemic Lupus Erythematosus|Psoriasis|Behcet's Disease|Wegener's Granulomatosis|Takayasu's Disease|Crohn's Disease|Ulcerative Colitis|Autoimmune Hepatitis|Sclerosing Cholangitis|Gougerot-sjögren|Idiopathic Thrombocytopenic Purpura|Systemic Sclerosis
Interventions: DRUG: Interleukin 2
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ZOE BIOME Study: Biotics Influence on Microbiome Ecosystem
Status: RECRUITING
Conditions: Gut Microbiome|Prebiotic|Probiotic|Postprandial Period
Interventions: OTHER: Prebiotic-like nut and seed mix|OTHER: Bread Crouton|DIETARY_SUPPLEMENT: Probiotic capsule|OTHER: White bread and low fat spread
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Toripalimab in Combination With Platinum Plus Etoposidein Patients With Extensive-Stage Small Cell Lung Cancer
Status: UNKNOWN
Conditions: Small Cell Lung Cancer
Interventions: DRUG: TORIPALIMAB INJECTION(JS001 ) Carboplatin Cisplatin Etoposide Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Utility of Continuous Pulse Oximetry for Pediatric Patients With Stable Respiratory Illness
Status: COMPLETED
Conditions: Respiratory Disease|Asthma in Children|Pneumonia in Children|Bronchiolitis Acute
Interventions: DEVICE: Continous Pulse oximeter|DEVICE: Intermittent Pulse oximeter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Addition of P1101 to Imatinib Treatment in Patients With Chronic Phase Chronic Myeloid Leukaemia Not Achieving a Complete Molecular Response
Status: COMPLETED
Conditions: Chronic Phase Chronic Myeloid Leukemia
Interventions: DRUG: P1101
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Inland Norway Healthy Life Center Study
Status: NOT_YET_RECRUITING
Conditions: Non-Communicable Chronic Diseases|Obesity|Insulin Resistance|Musculoskeletal Diseases|Psychological Disorder|Cardiovascular Diseases
Interventions: OTHER: Physical activity
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Liquid Biopsies for the Personalized Management of Patients With Hereditary Diffuse Gastric Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Hereditary Diffuse Gastric Cancer
Interventions: GENETIC: Liquid biopsies (blood, gastric fluid).
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Photobiomodulation With Red and Infrared LED Device for Temporomandibular Dysfunction
Status: UNKNOWN
Conditions: Temporomandibular Disorder
Interventions: RADIATION: LED photobiomodulation|RADIATION: Placebo LED photobiomodulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Omega 3 and Vitamin E Supplementation on the Serum Antioxidant Enzymes and Gene Expressions of PGC-1a, h TERT, FOXOs and SIRTs in CAD Patients
Status: UNKNOWN
Conditions: Coronary Artery Disease
Interventions: DIETARY_SUPPLEMENT: omega 3|DIETARY_SUPPLEMENT: vitamin E|DIETARY_SUPPLEMENT: placebo of omega 3|DIETARY_SUPPLEMENT: placebo of vitamin E
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Multiple Daily Doses Of Aspirin To Overcome Aspirin Hyporesponsiveness Post Cardiac Bypass Surgery
Status: COMPLETED
Conditions: Postoperative; Dysfunction Following Cardiac Surgery
Interventions: DRUG: Aspirin|DRUG: Aspirin|DRUG: Aspirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Double-blind Study to Investigate Efficacy, Safety and Tolerability of BAY1142524 in Patients With Type II Diabetes and a Clinical Diagnosis of Diabetic Kidney Disease
Status: COMPLETED
Conditions: Diabetic Kidney Disease
Interventions: DRUG: Fulacimstat (BAY1142524)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Deltoid Ligament Repair in Patients With Weber B Ankle Fracture; Randomized Controlled Trial.
Status: NOT_YET_RECRUITING
Conditions: Weber B Ankle Fractures
Interventions: PROCEDURE: Deltoid ligament repair
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Pioglitazone and Evogliptin on Hepatic Fibrosis in Patients With Chronic Hepatitis B With Type 2 Diabetes
Status: UNKNOWN
Conditions: Hepatitis B, Chronic|Fibrosis, Liver|Diabetes Mellitus, Type 2
Interventions: DRUG: Pioglitazone 15 Mg Oral Tablet|DRUG: Evogliptin 5mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exercise and Diet for Pediatric Obesity
Status: COMPLETED
Conditions: Pediatric Obesity|COVID-19
Interventions: OTHER: High-intensity aerobic training with high protein diet|OTHER: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Comparison of Graft Quality and Patient Morbidity Following Palatal Harvesting.
Status: COMPLETED
Conditions: Gingival Recession|Palate; Wound
Interventions: PROCEDURE: DGG Harvesting approach|PROCEDURE: ET harvesting approach|PROCEDURE: TDT harvesting approach|PROCEDURE: MT harvesting approach|PROCEDURE: Root coverage procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Carboplatin and Paclitaxel in Treating Patients With Locally Recurrent or Metastatic Nasopharyngeal Cancer
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: DRUG: carboplatin|DRUG: paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Erythritol Air Polishing in Mucositis Treatment
Status: RECRUITING
Conditions: Peri-implant Mucositis
Interventions: PROCEDURE: Air-polishing with erythritol at different time points|PROCEDURE: Single Air-polishing with erythritol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adjuvant Therapy of Pegylated Interferon- 2b Plus Melanoma Peptide Vaccine
Status: COMPLETED
Conditions: Melanoma
Interventions: DRUG: Pegylated Interferon-Alfa 2b (PEG Intron)|DRUG: GP-100 Peptide Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of ActiSight™ Needle Guidance System in Patients Undergoing CT-Guided Procedures
Status: COMPLETED
Conditions: Lung Diseases|Liver Diseases
Interventions: DEVICE: ActiSight Needle Guidance System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Chronic Postherpetic Pain With Autologous Fat Grafting - A RCT
Status: COMPLETED
Conditions: Postherpetic Neuralgia|Shingles|Varicella Zoster|Herpes Zoster|Chronic Pain
Interventions: PROCEDURE: Autologous Fat Grafting / Fat Transplant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fibromyalgia of Less Than One Year Duration. Study of Pregabalin
Status: WITHDRAWN
Conditions: Fibromyalgia
Interventions: DRUG: Pregabalin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MR-guided High Intensity Focused Ultrasound (HIFU) on Pediatric Solid Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Relapsed Pediatric Solid Tumors|Refractory Pediatric Solid Tumors|Rhabdomyosarcoma|Ewing Sarcoma|Osteosarcoma|Neuroblastoma|Wilms Tumor|Hepatic Tumor|Germ Cell Tumor|Desmoid Tumor
Interventions: DEVICE: Magnetic Resonance High Intensity Focused Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CONTIGO - Informing Latinas About HBOC Risk
Status: ENROLLING_BY_INVITATION
Conditions: Hereditary Breast and Ovarian Cancer
Interventions: BEHAVIORAL: Culturally Targeted Narrative Video: "Is My Cancer Hereditary? Rosa Visits a Genetic Counselor."|BEHAVIORAL: FORCE Fact Sheet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effect of High-dose Remifentanil on Established Capsaicin-induced Hyperalgesia in Human Volunteers
Status: UNKNOWN
Conditions: Hyperalgesia
Interventions: DRUG: Remifentanil|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Randomized Clinical Trial to Evaluate Immunogenicity and Safety in Mexicans Newborns
Status: UNKNOWN
Conditions: Poliomyelitis
Interventions: BIOLOGICAL: Trivalent OPV Birmex|BIOLOGICAL: Trivalent OPV Sanofi Pasteur
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose:
Clinical trial: Communication Practices to Develop the Health Literacy Competencies in Nursing Students
Status: COMPLETED
Conditions: Health Literacy|Competence|Nursing Students
Interventions: BEHAVIORAL: Multimodal intervention (communication and education simulations) for EG1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Acalabrutinib Safety Study in Untreated and Relapsed or Refractory Chronic Lymphocytic Leukemia Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Lymphocytic Leukemia
Interventions: DRUG: Acalabrutinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: E-B-FAHF-2, Multi OIT and Xolair (Omalizumab) for Food Allergy
Status: UNKNOWN
Conditions: Food Allergy
Interventions: DRUG: Chinese Herbal Medication|DRUG: Placebo|DRUG: Omalizumab|DRUG: Multi OIT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Efficacy of EV06 Ophthalmic Solution in Improving Vision in Subjects With Presbyopia
Status: COMPLETED
Conditions: Presbyopia
Interventions: DRUG: EV06 Ophthalmic Solution|DRUG: Placebo Ophthalmic Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: LIFU for Treatment for Refractory Opioid Use Disorder
Status: RECRUITING
Conditions: Opioid Use Disorder
Interventions: DEVICE: Low Intensity Focussed Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Study Evaluating Autologous CD30.CAR-T Cells in Patients With Relapsed/Refractory Hodgkin Lymphoma (CHARIOT)
Status: ACTIVE_NOT_RECRUITING
Conditions: Hodgkin Lymphoma, Adult|Hodgkin Disease Recurrent|Hodgkin Disease Refractory|Hodgkin Disease, Pediatric
Interventions: DRUG: CD30.CAR-T|DRUG: Fludarabine|DRUG: Bendamustine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Two Separate But Identical Studies Evaluating the Safety and Efficacy of ALTROPANE® in the Use of SPECT Imaging for Upper Extremity Tremor
Status: UNKNOWN
Conditions: Parkinsonian Syndromes
Interventions: DRUG: 123 I - ALTROPANE®
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Pembrolizumab and Itacitinib (INCB039110) for Non-Small Cell Lung Cancer
Status: TERMINATED
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: Itacitinib|BIOLOGICAL: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of a Self-management App in Improving the Control of Asthma Among School Adolescents
Status: NOT_YET_RECRUITING
Conditions: Asthma
Interventions: DEVICE: The KmAsthma self-management smart phone app intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Effects of MDMA-like Substances in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: 3,4-methylenedioxymethamphetamine|DRUG: 3,4-methylenedioxyamphetamine|DRUG: lysine-3,4-methylenedioxymethamphetamine|DRUG: lysine-3,4-methylenedioxyamphetamine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: 131MIBG to Treat Malignant Pheochromocytoma
Status: COMPLETED
Conditions: Pheochromocytoma
Interventions: DRUG: [131]I-MIBG|DRUG: 6-[18F]Fluorodopamine|DRUG: [123]I-MIBG
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Vestibular Function and Vestibular Rehabilitation in SSHL With Vertigo
Status: UNKNOWN
Conditions: Vestibular Disorder
Interventions: BEHAVIORAL: Vestibular rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Long-Term Schroth Exercises on Scoliosis Severity and Quality of Life in Braced AIS Individuals
Status: COMPLETED
Conditions: Adolescent Idiopathic Scoliosis
Interventions: OTHER: Scroth and brace|DEVICE: Brace
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: BENdamustine at Elevated Dose for Relapsed Follicular Lymphoma in Intensification Therapy and Transplantation (BENEFIT)
Status: TERMINATED
Conditions: Follicular Lymphoma
Interventions: DRUG: BeEAM
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Benefit of Paramedical Care in Accompanying Caregivers of Patients That Had Surgery for an Head and Neck Invasive Cancer
Status: RECRUITING
Conditions: Head and Neck Cancer
Interventions: OTHER: Accompanying caregivers by paramedical team
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of the Effect of Multiple Dosing With BI 201335 on CYP2B6 Metabolism and Effect of Multiple Dosing With Efavirenz on the Steady-state Pharmacokinetics of BI 201335 and on CYP3A4/5 Metabolism in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: low dose|DRUG: normal dose|DRUG: low dose
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comprehensive Aneurysm Management Trial
Status: RECRUITING
Conditions: Saccular Aneurysm|Intracranial Aneurysm|Unruptured Cerebral Aneurysm
Interventions: DEVICE: microsurgery; endovascular interventions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Creatine Supplementation and Resistance Training in Patients With Breast Cancer
Status: RECRUITING
Conditions: Breast Cancer|Supplementation|Resistance Training|Physical Performance|Quality of Life
Interventions: DIETARY_SUPPLEMENT: Creatine supplementation|OTHER: Resistance training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Immune Reconstitution of Lopinavir/Ritonavir-Based vs Efavirenz-based HAART in Advanced HIV Disease
Status: TERMINATED
Conditions: Acquired Immune Deficiency Syndrome
Interventions: DRUG: Lopinavir 400 mg/ritonavir 100 mg|DRUG: Efavirenz
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vedic Medical Astrology in Essential Hypertension
Status: COMPLETED
Conditions: Essential Hypertension
Interventions: COMBINATION_PRODUCT: Vedic Medical Astrology|OTHER: Placebo vedic medical astrology (PMA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: AG-013736 (Axitinib) In Patients With Poor Prognosis Acute Myeloid Leukemia (AML) Or Myelodysplastic Syndrome (MDS)
Status: COMPLETED
Conditions: Acute Myeloid Leukemia (AML)|Myelodysplastic Syndrome
Interventions: DRUG: AG-013736 (Axitinib)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PReventive Efficacy and Safety of rEbamipide on Nsaid Induced Mucosal Toxicity
Status: COMPLETED
Conditions: Rheumatoid Arthritis|Osteoarthritis|Ankylosing Spondylitis
Interventions: DRUG: Rebamipide|DRUG: Misoprostol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Adhesiveness of Coronary Drug-Eluting Stents to the Delivery Balloon-Catheter: A Randomized Comparison
Status: UNKNOWN
Conditions: Coronary Artery Disease
Interventions: PROCEDURE: Percutaneous coronary intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics Study of Colchicine in Familial Mediterranean Fever (FMF) Patients
Status: COMPLETED
Conditions: Familial Mediterranean Fever
Interventions: DRUG: colchicine sprinkle capsules|DRUG: colchicine sprinkle capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Validations of New cut-of for the Stratification of Postoperative Complications,Drains Management
Status: UNKNOWN
Conditions: Pancreas Cancer|Pancreatic Fistula
Interventions: PROCEDURE: Surgical Drains Management
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low Dose Aspirin for Venous Leg Ulcers
Status: COMPLETED
Conditions: Venous Leg Ulcer
Interventions: DRUG: Aspirin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Tolerability and Pharmacokinetic of BI 409306
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Placebo|DRUG: Placebo|DRUG: BI 409306|DRUG: BI 409306
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Phase 1 PK, Bioavailability, Safety Study of Clonidine MBT w Catapres in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Clonidine MBT 50µg|DRUG: Clonidine MBT 100µg|DRUG: Catapres 100μg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomization of Single vs Multiple Arterial Grafts
Status: ACTIVE_NOT_RECRUITING
Conditions: Coronary Artery Disease|Heart Diseases
Interventions: PROCEDURE: Single arterial graft|PROCEDURE: Multiple arterial grafting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized, Double-Blind Placebo-Controlled Peanut Sublingual Immunotherapy Trial
Status: COMPLETED
Conditions: Food Hypersensitivity|Hypersensitivity|Immediate Hypersensitivity|Peanut Hypersensitivity
Interventions: DRUG: Glycerinated peanut allergenic extract|DRUG: Placebo for peanut extract (glycerin)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Liver Glycogen and Hypoglycemia in Humans
Status: ACTIVE_NOT_RECRUITING
Conditions: Hypoglycemia; Iatrogenic
Interventions: DRUG: Low Fructose|DRUG: Saline|DRUG: Somatostatin|DRUG: Insulin|DRUG: Glucagon|DRUG: Dextrose solution|DRUG: High Fructose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Orbital Radiotherapy in Grave's Ophthalmopathy 1 Week vs 2 Weeks (OraGO-1 Trial)
Status: NOT_YET_RECRUITING
Conditions: Thyroid Associated Ophthalmopathy
Interventions: RADIATION: Short course radiation therapy|RADIATION: Standard course radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multimodal Morpho-functional Study in Glaucoma Patients-Citicoline Oral Solution
Status: RECRUITING
Conditions: Primary Open Angle Glaucoma
Interventions: DIETARY_SUPPLEMENT: Citicoline|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomised, Cross-over, Relative Bioavailability Study of Nicotine Delivery and Nicotine Extraction From Oral Products
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: OTHER: A|OTHER: B|OTHER: C|OTHER: D|OTHER: E
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Comparison of Reduced Fluence Versus Standard Photodynamic Therapy (in Combination With Intravitreal Triamcinolone Acetate)
Status: COMPLETED
Conditions: Macular Degeneration
Interventions: PROCEDURE: Photodynamic therapy and intravitreal triamcinolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Pharmacokinetics of Besylsartan Tablet in Healthy Male Subject
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Besylsartan|DRUG: Amosartan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Estrogen on Fear Extinction R61
Status: COMPLETED
Conditions: Fear|Fear; Examination, Phobic
Interventions: DRUG: Estradiol 2Mg Tablet|DRUG: Estradiol 4Mg Tablet|DRUG: Placebo Pills
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Phase 3 Clinical Trials for Bowel Preparation for Colonoscopy
Status: ACTIVE_NOT_RECRUITING
Conditions: Bowel Preparation
Interventions: DRUG: CTP0302-A|DRUG: CTP0302-B|DRUG: Conventional OST
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dexmedetomidine or Fentanyl as Additives to Epidural Levobupivacaine in Painless Labor
Status: COMPLETED
Conditions: Epidural Analgesia|Painless Labor|Dexmedetomidine|Fentanyl|Levobupivacaine
Interventions: DRUG: levobupivacaine|DRUG: Dexmedetomidine|DRUG: Fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: MDMA-assisted Massed Prolonged Exposure for PTSD
Status: NOT_YET_RECRUITING
Conditions: Post-Traumatic Stress Disorder
Interventions: DRUG: 3,4 Methylenedioxymethamphetamine|BEHAVIORAL: Prolonged Exposure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Ground and Unground Enamel on the Clinical Performance of Direct Composite Build-ups
Status: ACTIVE_NOT_RECRUITING
Conditions: Trial of Labor; Failure
Interventions: OTHER: Direct composite build-ups
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SCREENING
Clinical trial: Motivational Interviewing for Adult Kidney Transplant Recipients
Status: UNKNOWN
Conditions: Motivational Interviewing|Adult|Kidney Transplantation|Self-Management|Treatment Adherence|Medication Adherence|Patient Outcome Assessment
Interventions: BEHAVIORAL: Motivational Interviewing for Adult Kidney Transplant Recipients|OTHER: Routine care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Feasibility Trial of a Single Session of Crisis Response Planning for Youth at High Risk for Suicide
Status: RECRUITING
Conditions: Suicide Prevention
Interventions: BEHAVIORAL: Virtual Crisis Response Planning|BEHAVIORAL: In-Person Crisis Response Planning|BEHAVIORAL: Crisis Risk Counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Phase 1b Study of the Selective HDAC Inhibitor Mocetinostat in Combination With Ipilimumab and Nivolumab in Patients With Unresectable Stage III or Stage IV Melanoma
Status: TERMINATED
Conditions: Melanoma
Interventions: DRUG: Mocetinostat Induction Phase + Ipilimumab + Nivolumab|DRUG: Mocetinostat Maintenance Phase + Ipilimumab + Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Reduced Dosing of the Nonavalent HPV Vaccine in Women Living With HIV
Status: RECRUITING
Conditions: HPV|Human Papilloma Virus|Human Immunodeficiency Virus
Interventions: BIOLOGICAL: Nonavalent HPV vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: M-Vax + Low Dose Interleukin-2 Versus Placebo Vaccine in Metastatic Melanoma in Patients With Stage IV Melanoma
Status: UNKNOWN
Conditions: Melanoma
Interventions: BIOLOGICAL: M-Vax- autologous, hapten-modified melanoma vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of a Probiotic Formula on Reducing SIBO in IBS Patients
Status: TERMINATED
Conditions: Irritable Bowel Syndrome|Small Intestinal Bacterial Overgrowth
Interventions: DIETARY_SUPPLEMENT: Probiotic|DRUG: Rifaximin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Smoking Cessation Programme in Workplaces in Hong Kong (Phase IV)
Status: COMPLETED
Conditions: Smoking Cessation
Interventions: BEHAVIORAL: Occupational-specific health talk|BEHAVIORAL: WhatsApp interaction|BEHAVIORAL: Phone follow-up/counselling service|BIOLOGICAL: Text message
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Intravesical Instillation of Botulinum Toxin Type A to Patients With Urge Urinary Incontinence
Status: UNKNOWN
Conditions: Urge Urinary Incontinence
Interventions: DRUG: botulinum toxin type A
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Study of Nivolumab+Ipilimumab+/- SBRT for Metastatic Merkel Cell Carcinoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Merkel Cell Carcinoma|Skin Cancer
Interventions: DRUG: Nivolumab|DRUG: Ipilimumab|RADIATION: Stereotactic Body Radiation Therapy (SBRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial to Evaluate the Efficacy and Safety of Two Concentrations of VBP-926 Solution for the Treatment of Chemotherapy-associated Paronychia in Cancer Patients
Status: COMPLETED
Conditions: Chemotherapy-Associated Paronychia
Interventions: DRUG: VBP-926
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study of Optimized CT-guided Pulmonary Nodule Microcoil Localization Technique
Status: COMPLETED
Conditions: Pulmonary Nodule, Solitary
Interventions: PROCEDURE: Optimized Localization Technique
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose-escalation by Hypofractionated Stereotactic Radiotherapy for Brain Metastases in Non Small Cell Lung Cancer
Status: RECRUITING
Conditions: Non Small Cell Lung Cancer|Stage IV Non-small Cell Lung Cancer|Brain Metastases
Interventions: RADIATION: Hypofractionated Stereotactic Radiotherap
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tailored Anti-platelet Therapy After DES Implantation in High-risk Patients
Status: RECRUITING
Conditions: Coronary Artery Disease
Interventions: DRUG: Clopidogrel monotherapy|DRUG: Tailored anti-platelet therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of VIR-2482 in Healthy Volunteers
Status: COMPLETED
Conditions: Influenza A
Interventions: DRUG: VIR-2482|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Phase I/II Trial of Radiation, Avastin and Tarceva for Pancreatic Adenocarcinoma
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DRUG: Avastin|DRUG: Tarceva|RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: General Anesthesia for Endovascular Thrombectomy; A Pilot Study.
Status: COMPLETED
Conditions: Stroke|Cerebrovascular Stroke|Brain Ischemia|Brain Diseases|Cardiovascular Diseases|Central Nervous System Diseases|Cerebrovascular Disorders|Nervous System Diseases|Vascular Diseases
Interventions: DRUG: Sevoflurane|DRUG: Lidocaine
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Gliadel, XRT, Temodar, Avastin Followed by Avastin, Temodar for Newly Diagnosed Glioblastoma Multiforme (GBM)
Status: TERMINATED
Conditions: Glioblastoma Multiforme|Gliosarcoma
Interventions: DRUG: Gliadel|RADIATION: Radiation Therapy|DRUG: Avastin|DRUG: Temodar
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: First-pass Recanalization With EmboTrap II in Acute Ischemic Stroke (FREE-AIS)
Status: UNKNOWN
Conditions: Acute Ischemic Stroke Due to Intracranial Large Artery Occlusion
Interventions: DEVICE: Thrombectomy using EmboTrap II
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The PATH Study to Promote Physical Activity After Knee Replacement
Status: COMPLETED
Conditions: Knee Arthroplasty
Interventions: BEHAVIORAL: Standard Physical Therapy|BEHAVIORAL: Physical therapist discuss aerobic physical activity|BEHAVIORAL: Physical activity session
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Outcomes of Patients Who Survived Treatment on an Intensive Care Unit for COVID-19 in England and Wales
Status: ACTIVE_NOT_RECRUITING
Conditions: Covid19|Myocardial Infarction|Stroke|Critical Illness|Heart Failure|Deep Vein Thrombosis|Pulmonary Embolism|Renal Failure
Interventions: OTHER: Not applicable as observational study
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Trial to Assess the Safety, Tolerability and Pharmacokinetics of MDT-637 in Healthy Volunteers
Status: COMPLETED
Conditions: Drug Safety
Interventions: DRUG: MDT-637|DRUG: MDT-637
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety And Efficacy Study Of Sunitinib Malate As First-Line Systemic Therapy In Chinese Patients With Metastatic Renal Cell Carcinoma
Status: COMPLETED
Conditions: Carcinoma, Renal Cell
Interventions: DRUG: Sunitinib Malate (SU011248)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reversal of Remimazolam by a Single Dose of Flumazenil
Status: COMPLETED
Conditions: Flumazenil Adverse Reaction|Ambulatory Surgery|Postoperative Nausea|Remimazolam
Interventions: DRUG: Flumazenil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Effectiveness of Dry Needling for Treating Shoulder Pain
Status: COMPLETED
Conditions: Chronic Shoulder Pain
Interventions: OTHER: Active Dry Needling|OTHER: Sham Dry needling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Left Versus Right Transradial Approach for Percutaneous Coronary Procedures
Status: COMPLETED
Conditions: Coronary Angiography|Angioplasty, Transluminal, Percutaneous Coronary
Interventions: PROCEDURE: Right radial|PROCEDURE: left radial
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Budesonide With Intratracheal Surfactants in Extremely Preterm Infants
Status: UNKNOWN
Conditions: Bronchopulmonary Dysplasia|Respiratory Distress Syndrome in Premature Infant
Interventions: DRUG: Budesonide in bovine lipid extract surfactant (BLES)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Role of Sleep Reactivity in Shift Work Disorder
Status: RECRUITING
Conditions: Shift-work Disorder
Interventions: BEHAVIORAL: Active phototherapy|BEHAVIORAL: Control phototherapy|BEHAVIORAL: Cognitive Behavioral Therapy (CBT)|BEHAVIORAL: Sleep education control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Acute and Subacute Iliofemoral and/or Caval Deep Vein Thrombosis: Evaluation of Mechanical Thrombectomy Systems
Status: NOT_YET_RECRUITING
Conditions: Thrombosis, Venous
Interventions: OTHER: mechanical thrombectomy of caval and iliofemoral veins
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Assess the Safety, Tolerability, and Pharmacokinetics of AZD5462 Following Single and Multiple Ascending Dose Administration to Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DRUG: AZD5462|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: CORonaRy Angiography and intErventions Via Distal vs Proximal aCcess
Status: RECRUITING
Conditions: Coronary Angiography|Coronary Artery Disease
Interventions: PROCEDURE: Use of radial artery for access for a coronary angiography or intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pelvic Pain Treated With MR-guided Cryoanalgesia
Status: WITHDRAWN
Conditions: Pelvic Pain Syndrome|Groin Pain|Meralgia Paresthetica|Low Back Pain|Perineal Neuralgia
Interventions: DEVICE: MR neurography-guided cryoanalgesia
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vibratory PEP Device and Hospital Length of Stay for Acute Exacerbation of COPD
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DEVICE: Acapella Vibratory PEP Therapy Device plus usual care|DEVICE: Sham Acapella Vibratory PEP Device plus usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Impact of Computerized Decision Support for ANTIBIOtic Prescription in Cancer Patients With Febrile NEutropenia in the Emergency Department on Treatment Failure.
Status: UNKNOWN
Conditions: Febrile Neutropenia
Interventions: OTHER: routine care|OTHER: Computerized Decision support app (CDSA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Trial of SHR-1210 (an Anti-PD-1 Inhibitor) in Combination With FOLFOX4 in Subjects With Advanced HCC Who Have Never Received Prior Systemic Treatment.
Status: UNKNOWN
Conditions: Advanced Hepatocellular Carcinoma
Interventions: DRUG: SHR-1210|DRUG: FOLFOX4|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Alectinib in RET-rearranged Non-small Cell Lung Cancer or RET-mutated Thyroid Cancer
Status: TERMINATED
Conditions: ALK-positive Non-small Cell Lung Cancer (NSCLC)|RET-positive Non-small Cell Lung Cancer (NSCLC)|RET-positive Thyroid Cancer
Interventions: DRUG: Alectinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Popliteal Sciatic Nerve Block Catheter Placement for Foot Surgery
Status: COMPLETED
Conditions: Foot Surgery|Ankle Surgery
Interventions: PROCEDURE: Placement of nerve block catheter|PROCEDURE: Placement of nerve block catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Screen to Save 2: Rural Cancer Screening Educational Intervention
Status: COMPLETED
Conditions: Cancer|Colorectal Cancer|Lung Cancer
Interventions: OTHER: In-person cancer screening education|OTHER: Online educational video and website module|OTHER: Online educational video|OTHER: Message from healthcare system and online educational video and website module
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SCREENING
Clinical trial: Effect of Probiotics on the Digestibility and Immunity in Infants
Status: COMPLETED
Conditions: Gastrointestinal Tract Flora Composition
Interventions: DRUG: Biostime probiotics sachet children's formula|DRUG: Biostime probiotics sachet children's formula（placebo）
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION