pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Buprenorphine for Cancer Pain
Status: RECRUITING
Conditions: Cancer-Related Pain
Interventions: DRUG: Use of buprenorphine with FAO > 30 OME|BEHAVIORAL: CPM Rx application use
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Umbilical Cord Blood Derived MAK Immune Cells Combined With Standard Second-Line Treatments for Hepatobiliary and Pancreatic Malignancies
Status: NOT_YET_RECRUITING
Conditions: Stage IV Pancreatic Cancer|Hepatocellular Carcinoma , Cholangiocarcinoma
Interventions: BIOLOGICAL: Umbilical Cord Blood Derived MAK Immune Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Acetazolamide on Cognition in Patients With Respiratory Disease at Altitude
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: DRUG: ACETAZOLAMIDE oral capsule|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Dexrazoxane as a Protective Agent in Anthracycline Treated Breast Cancer
Status: TERMINATED
Conditions: Breast Cancer
Interventions: DRUG: Dexrazoxane hydrochloride|DRUG: Dexrazoxane hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RBN-2397 in Combination With Pembrolizumab in Patients With SCCL
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Squamous Non-Small Cell Lung Carcinoma
Interventions: DRUG: RBN-2397
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vitamin D Supplementation in HIV
Status: COMPLETED
Conditions: HIV-infection/Aids
Interventions: DIETARY_SUPPLEMENT: Vitamin D3|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Individualized Blood Pressure Management in Patients Undergoing Cardiac Surgery
Status: WITHDRAWN
Conditions: Cardiac Surgery
Interventions: OTHER: Individualized intraoperative BP management|OTHER: Standard intraoperative BP management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study to Determine the Difference in Reduction of Bioaerosols in a Long-term Care Facility
Status: NOT_YET_RECRUITING
Conditions: Air Pollution
Interventions: OTHER: Use of C-Polar coated HVAC Filter versus conventional HVAC Filter
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Extension of Phase 3 Gene Therapy for Painful Diabetic Neuropathy
Status: COMPLETED
Conditions: Painful Diabetic Neuropathy|Diabetic Neuropathy, Painful
Interventions: GENETIC: Long-Term Follow-Up of Patients who Received Engensis (VM202)|DRUG: Long-Term Follow-Up of Patients who Received Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Topical Nepafenac 0.1% on Pain Related to Intravitreal Injections
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Nepafenac Eye Drops|DRUG: Placebo (Artificial Tears)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Antibiotic Prophylaxis for TEVAR
Status: ACTIVE_NOT_RECRUITING
Conditions: Aortic Dissection|Aortic Diseases|Aortic Aneurysm, Thoracic|Coarctation of Aorta|Hematoma; Aorta
Interventions: PROCEDURE: thoracic endovascular aortic repair
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy of Guided Tissue Regeneration in the Healing of Periapical Defects With Periodontal Communication Using CBCT
Status: UNKNOWN
Conditions: Apico Marginal Defects
Interventions: PROCEDURE: Periapical surgery with amniotic membrane|PROCEDURE: periapical surgery without amniotic membrane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Glutamatergic Modulation of Cocaine-related Deficits
Status: COMPLETED
Conditions: Cocaine Dependence
Interventions: DRUG: Ketamine 0.41 mg/kg|DRUG: Ketamine 0.71 mg/kg|DRUG: Lorazepam 2 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MRI Simulation-guided Boost in Short-course Preoperative Radiotherapy for Unresectable Rectal Cancer
Status: RECRUITING
Conditions: Rectal Neoplasms
Interventions: RADIATION: SCPRT|RADIATION: CRT|DRUG: CAPOX
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Safety and Efficacy of Sitagliptin Addition During Metformin Up-titration (MK-0431-848)
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Sitagliptin|DRUG: Placebo|DRUG: Metformin IR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Double-syringe vs Single-syringe Technique of Adenosine for Termination of Regular Narrow Complex Tachycardia
Status: RECRUITING
Conditions: Supraventricular Tachycardia
Interventions: PROCEDURE: Single-syringe diluted with normal saline technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Sub-total Parathyroidectomy Reduces Vascular Calcification in Haemodialysis Patients
Status: UNKNOWN
Conditions: Hemodialysis
Interventions: PROCEDURE: Sub-total Parathyroidectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Partnered Dance Aerobic Exercise as a Neuroprotective, Motor and Cognitive Intervention in Parkinson's Disease
Status: RECRUITING
Conditions: Parkinson's Disease|Exercise Therapy|Cognition
Interventions: BEHAVIORAL: PDAE|BEHAVIORAL: WAE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Prevention of Cow's Milk Allergy in Children
Status: COMPLETED
Conditions: Milk Hypersensitivity
Interventions: OTHER: Fermented milk|OTHER: Standard milk
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Assessment of the Effect of Restriction on Alimentary AGE in Progression of Chronic Kidney Disease
Status: NOT_YET_RECRUITING
Conditions: Kidney Failure, Chronic|Chronic Kidney Disease stage3|Chronic Kidney Disease Stage 3B|Chronic Kidney Disease Stage 3A (Disorder)|Chronic Kidney Disease, Stage 3 (Moderate)|Diet Habit
Interventions: BEHAVIORAL: Low-AGE diet|BEHAVIORAL: High-AGE diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Bone Mineral Density, Body Composition and Growth Following Severe Burn Injury
Status: TERMINATED
Conditions: Burn|Growth|Malnutrition
Interventions: DIETARY_SUPPLEMENT: Calcium, Vitamin D|DIETARY_SUPPLEMENT: Calcium,Vitamin D|DIETARY_SUPPLEMENT: Calcium, VitaminD|OTHER: Sugar Pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: RiSE to Prevent Cardiovascular Disease in African Americans
Status: COMPLETED
Conditions: Atherosclerosis|Stress|Hypertension|Dyslipidemias|Obesity|Diabetes|Coronary Artery Disease
Interventions: BEHAVIORAL: Resilience, Stress, and Ethnicity (RiSE)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Neuroprotection During Open Heart Surgery
Status: COMPLETED
Conditions: Open Heart Surgery
Interventions: DRUG: Ketofol (propofol to ketamine ratio 1:1)|DRUG: propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Randomized Clinical Trial of Standard FMT Treatments
Status: WITHDRAWN
Conditions: Clostridium Difficile
Interventions: DRUG: PRIM-DJ2727
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Brain Gym Therapy on Quality of Sleep Among Elderly People
Status: NOT_YET_RECRUITING
Conditions: Sleep Disorder|Insomnia|Cognitive Function Abnormal|Old Age; Debility|Brain Gym Therapy
Interventions: OTHER: Brain Gym Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of Samsca on Control of Hyponatremia and Extracellular Fluid in Cirrhotic Patients With Ascites
Status: TERMINATED
Conditions: Hyponatremia and Extracellular Fluid in Cirrhotic
Interventions: DRUG: Tolvaptan|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Testing an Integrated Bio-Behavioral Primary HIV Prevention Intervention Among High-Risk People Who Use Drugs
Status: COMPLETED
Conditions: Risk Behavior|HIV/AIDS|Medication Adherence|Substance Abuse
Interventions: OTHER: CHRP-BB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Investigation of Dynamic Hyperinflation and Its Relationship With Functional Exercise Capacity in Children With Bronchiectasis
Status: COMPLETED
Conditions: Bronchiectasis
Interventions: OTHER: Respiratory assessment using "Spiropalm 6MWT" portable spirometry|OTHER: Evaluation of functional exercise capacity|OTHER: Evaluation of peripheral muscle strength|OTHER: Evaluation of chronic cough
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Hyperbaric Oxygen Therapy Compared to Cognitive Training in FASD
Status: NOT_YET_RECRUITING
Conditions: FASD
Interventions: DEVICE: Hyperbaric Oxygen|BEHAVIORAL: Cognitive training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cell Salvage During Caesarean Section (CSCS)
Status: UNKNOWN
Conditions: Blood Transfusion
Interventions: COMBINATION_PRODUCT: intra-operative cell salvage|COMBINATION_PRODUCT: allogeneic blood transfusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Quality of Life in Patients With Allergic Rhinitis: Clinical Trial With Bilastine or Loratadine
Status: COMPLETED
Conditions: Allergic Rhinitis
Interventions: DRUG: Bilastine|DRUG: Loratadine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Research of Circulating Tumor Cells Released During Cervical Cancer Surgery
Status: SUSPENDED
Conditions: Cervical Cancer Stage IA1|Cervical Cancer Stage IB1|Cervical Cancer Stage IA2|Cervical Cancer Stage IB2
Interventions: OTHER: Blood samples
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy, Safety, and Withdrawal and Retreatment With Brodalumab in Moderate to Severe Plaque Psoriasis Subjects
Status: TERMINATED
Conditions: Psoriasis
Interventions: DRUG: 210 mg brodalumab|DRUG: 140 mg brodalumab|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Transcranial Magnetic Stimulation on Recovery of Upper Limb Among Stroke Survivors
Status: COMPLETED
Conditions: Stroke
Interventions: DEVICE: Transcranial magnetic stimulation (TMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Topical SGX302 for Mild-to-Moderate Psoriasis
Status: RECRUITING
Conditions: Psoriasis|Plaque Psoriasis|Psoriasis Vulgaris
Interventions: DRUG: Hypericin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Physical Activity Immediately After Acute Cerebral Ischemia
Status: UNKNOWN
Conditions: Acute Ischemic Stroke|Physical Activity|Accelerometer
Interventions: BEHAVIORAL: physical activity 15 minutes/day|BEHAVIORAL: physical activity, 2 x 30 minutes/day
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ex Vivo-Activated Lymph Node Lymphocytes in Treating Patients With Stage IIIC-IV Melanoma
Status: TERMINATED
Conditions: Stage IIIC Skin Melanoma|Stage IV Melanoma
Interventions: PROCEDURE: lymph node|BIOLOGICAL: X-ACT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Camrelizumab With AC in Patients With Brain Metastases of Driven Gene-negative,NSCLC
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-squamous Non-small-cell Lung Cancer|Brain Metastases
Interventions: DRUG: Camrelizumab|DRUG: Pemetrexed|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of AMD3100 (Plerixafor) and Rituximab in Patients With Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma
Status: COMPLETED
Conditions: Chronic Lymphocytic Leukemia (CLL)|Small Lymphocytic Lymphoma (SLL)
Interventions: DRUG: plerixafor
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy Followed By Vaccine Therapy Plus Sargramostim in Treating Patients With Stage III or Stage IV Non-Hodgkin's Lymphoma
Status: UNKNOWN
Conditions: Lymphoma
Interventions: BIOLOGICAL: autologous immunoglobulin idiotype-KLH conjugate vaccine|BIOLOGICAL: keyhole limpet hemocyanin|BIOLOGICAL: sargramostim|DRUG: cyclophosphamide|DRUG: prednisone|DRUG: vincristine sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: DIAGNOSIS of PULMONARY TUBERCULOSIS Through HUMAN BREATH (TBENOSE)
Status: COMPLETED
Conditions: Tuberculosis, Pulmonary|HIV Seropositivity
Interventions: DEVICE: Tor Vergata Electronic Nose (TV eNose)|OTHER: Survey & Physical Exam|DIAGNOSTIC_TEST: TB LAMP test|OTHER: Sputum Samples|OTHER: Chest X-Ray|OTHER: Follow Up 5 days after beginning of Tx.|OTHER: Follow Up & 15 days after beginning of Tx.|OTHER: Follow Up & 30 days after beginning of Tx.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of CXA-10 in Healthy Volunteers
Status: COMPLETED
Conditions: Acute Kidney Injury (Nontraumatic)
Interventions: DRUG: CXA-10 emulsion|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Implantation of Capsular Tension Ring in Primary Angle Closure Patients With Zonular Laxity or Dialysis
Status: NOT_YET_RECRUITING
Conditions: Glaucoma|Angle-Closure
Interventions: PROCEDURE: Capsular tension ring implantation|PROCEDURE: No capsular tension ring implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ph 1 Study in Subjects With Tumors Requiring Arginine to Assess ADI-PEG 20 With Pemetrexed and Cisplatin
Status: TERMINATED
Conditions: Pleural Mesothelioma Malignant Advanced|Peritoneal Mesothelioma Malignant Advanced|Non-squamous Non-small Cell Lung Carcinoma|Uveal Melanoma|Hepatocellular Carcinoma|Glioma|Sarcomatoid Carcinoma
Interventions: DRUG: ADI-PEG 20
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of Hesperidin and Vitamin C on Uric Acid Concentration
Status: COMPLETED
Conditions: Higher Uric Acid Concentrations (>5,5 mg/dl)|Healthy
Interventions: DIETARY_SUPPLEMENT: Control|DIETARY_SUPPLEMENT: Hesperidin|DIETARY_SUPPLEMENT: Vitamin C|DIETARY_SUPPLEMENT: Hesperidin + Vitamin C
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Ofatumumab and High-dose Methylprednisolone in Patients With Chronic Lymphocytic Leukemia (CLL)
Status: COMPLETED
Conditions: CLL
Interventions: DRUG: Ofatumumab/HDMP
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: FID-007 in Treating Participants With Advanced Solid Tumors
Status: RECRUITING
Conditions: Advanced Malignant Solid Neoplasm|Refractory Malignant Solid Neoplasm
Interventions: OTHER: Laboratory Biomarker Analysis|DRUG: PEOX-based Polymer Encapsulated Paclitaxel FID-007|OTHER: Pharmacokinetic Study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, and Antiviral Activity of ACH-0141625 or Placebo in Combination With Peginterferon and Ribavirin in Hepatitis C Virus (HCV) Positive Participants
Status: COMPLETED
Conditions: Hepatitis C
Interventions: DRUG: ACH-0141625 (Sovaprevir)|DRUG: ACH-0141625 (Sovaprevir)|DRUG: ACH-0141625 (Sovaprevir)|DRUG: Placebo|DRUG: Pegylated Interferon alpha-2a|DRUG: Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Radio-Immunotherapy Before Cystectomy in Locally Advanced Urothelial Carcinoma of the Bladder
Status: UNKNOWN
Conditions: Urinary Bladder Cancer
Interventions: DRUG: Nivolumab|RADIATION: Radiation therapy of the pelvis|PROCEDURE: Radical cystectomy with standardized pelvic lymphadenectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Drug Interaction Between Revaprazan and Itopride HCl in Healthy Male Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: Sequence 1|OTHER: Sequence 2|OTHER: Sequence 3|OTHER: Sequence 4|OTHER: Sequence 5|OTHER: Sequence 6
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Liposomal Paclitaxel Combined Nedaplatin in Treatment of Advanced or Recurrent Esophageal Carcinoma
Status: COMPLETED
Conditions: Esophageal Carcinoma
Interventions: DRUG: Liposomal Paclitaxel|DRUG: Nedaplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Utility of an EEC for Assessing Efficacy of SIT in Pivotal Clinical Trials
Status: TERMINATED
Conditions: Allergic Rhinoconjunctivitis|Healthy Volunteers
Interventions: DRUG: Placebo|BIOLOGICAL: Allergovit 6-grasses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Therapeutic Drug Monitoring and Continuous Infusion of Beta-lactam Antibiotics in Patients With Bacteraemia
Status: WITHDRAWN
Conditions: Bacteremia
Interventions: DRUG: Continuous infusion of beta-lactam antibiotics .|OTHER: Therapeutic drug monitoring of beta-lactam antibiotics.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: METIMMOX: Colorectal Cancer METastasis - Shaping Anti-tumor IMMunity by OXaliplatin
Status: ACTIVE_NOT_RECRUITING
Conditions: Colorectal Cancer Metastatic
Interventions: DRUG: Nivolumab|DRUG: FLOX
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Use of Probiotics in Patients With Symptomatic Oral Lichen Planus
Status: COMPLETED
Conditions: Oral Lichen Planus|Candida Infection
Interventions: BIOLOGICAL: Probiotic lactobacilli reuteri|DRUG: Nystatin|DRUG: fluocinolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Theory Menu-Based Intervention on Vitamin D Adherence in People With Osteoporosis-Pilot Study
Status: COMPLETED
Conditions: Osteoporosis
Interventions: BEHAVIORAL: HAPA menu-based mini-video|BEHAVIORAL: Standard care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effects of Spinal Mobilizations on Symptoms, Neck 3D Movement, Neck Muscle Electromyography and Sympathetic Nervous System Activity in People With Neck Pain
Status: COMPLETED
Conditions: Neck Pain
Interventions: OTHER: Neck passive mobilizations|OTHER: Manual contact
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Feasibility to Reliably Measure Functional Abilities' Changes in Nonambulant Neuromuscular Patients Without Trial Site Visiting
Status: WITHDRAWN
Conditions: Spinal Muscular Atrophy|Neuromuscular Disorders
Interventions: OTHER: Direct current stimulation of cervical spinal cord
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Underutilization of Hospice Care in Older Black Adults
Status: ACTIVE_NOT_RECRUITING
Conditions: Hospice Care|Decision Aid|Decision-Making|Aging|Knowledge|Attitude
Interventions: OTHER: IDECIDE-HOSPICE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Use of Jet-injection in Photodynamic Therapy for Basal Cell Carcinoma
Status: ACTIVE_NOT_RECRUITING
Conditions: BCC|BCC - Basal Cell Carcinoma|Basal Cell Carcinoma|Basal Cell Cancer|Superficial Basal Cell Carcinoma|Nodular Basal Cell Carcinoma
Interventions: DRUG: Jet injection of ALA|PROCEDURE: Surgical excision|PROCEDURE: Illumination|OTHER: Incubation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Efficacy and Safety of HBM9161(HL161)Subcutaneous Injection in Patients With Generalized MG Patients
Status: COMPLETED
Conditions: Myasthenia Gravis
Interventions: DRUG: HBM9161 Injection (680mg)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Newborn Infant Parasympathetic Evaluation (NIPE) for Guiding Intraoperative Fentanyl in Children Under 2 Years
Status: COMPLETED
Conditions: Post Operative Pain|Analgesia|Children, Only|Narcotic Use
Interventions: PROCEDURE: NIPE monitor|PROCEDURE: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ZOLEDRONIC ASSOCIATED With Hight Hypofractionated Radiotherapy Dose in Bone Metastases Vertebral Prostate Adenocarcinoma
Status: COMPLETED
Conditions: Prostate Adenocarcinoma
Interventions: RADIATION: external radiotherapy|DRUG: Acide zoledronic
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Intranasal MSP-2017 (Etripamil) for the Conversion of PSVT to Sinus Rhythm
Status: COMPLETED
Conditions: Paroxysmal Supraventricular Tachycardia (PSVT)
Interventions: DRUG: Etripamil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess Adverse Events When Subcutaneous Risankizumab Injection is Given to Adult Participants With Psoriasis in Real World Setting
Status: WITHDRAWN
Conditions: Psoriasis
Interventions: DRUG: Risankizumab|BIOLOGICAL: Comparator 1|DRUG: Comparator 2
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Vandetanib and Bevacizumab in Treating Patients With Advanced Solid Tumors or Lymphoma
Status: COMPLETED
Conditions: Lung Cancer|Lymphoma|Lymphoproliferative Disorder|Small Intestine Cancer|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: BIOLOGICAL: bevacizumab|DRUG: vandetanib|OTHER: laboratory biomarker analysis|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Lidocaine for Pain After Urodynamic Testing
Status: COMPLETED
Conditions: Voiding Disorders|Overactive Bladder|Urinary Incontinence
Interventions: DRUG: Lidocaine gel 2%|OTHER: Standard lubricant gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Implementation Research on the Intervention Mode of " Comorbidity-Co-causes-Joint-prevention" Comprehensive Demonstration District of Depression and Obesity Among Children and Adolescents in Beijing
Status: NOT_YET_RECRUITING
Conditions: Depression|Obesity|High Risk of Depression|Overweight
Interventions: COMBINATION_PRODUCT: combination intervention strategy of [Comorbidity-Co-causes-Joint-prevention]|COMBINATION_PRODUCT: routine health education and mental health knowledge
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Anticoagulant Clinics and Vitamin K Antagonists
Status: COMPLETED
Conditions: Blood Coagulation Disorders
Interventions: DRUG: Anticoagulant (warfarin, acenocoumarol, fluindione)|DRUG: Anticoagulant (warfarin, acenocoumarol, fluindione)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Influence of Magnification and Clinical Experience on the Outcome of Pulpotomy in Mature Adult Teeth
Status: RECRUITING
Conditions: Irreversible Pulpitis
Interventions: OTHER: Adult full pulpotomy procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study for the Evaluation of the Safety and Performance of a Combined OCT System
Status: COMPLETED
Conditions: Healthy
Interventions: DEVICE: combined Coaxial Optical Coherence Tomography (OCT) System
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: ELO Water In Diabetes Care For Enhancement Of Blood Sugar Control
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: DIETARY_SUPPLEMENT: ELO Water|DIETARY_SUPPLEMENT: Placebo drinking water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Roll-Over Protocol To Provide Atv And/Or Truvada For Extended Access
Status: COMPLETED
Conditions: HIV
Interventions: DRUG: Atazanavir|DRUG: Atazanavir/Ritonavir|DRUG: Tenofovir/Emtricitabine|DRUG: Lopinavir/ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Interactions of Medicine and Exercise With Meal Timing
Status: RECRUITING
Conditions: Metabolic Syndrome, Protection Against|Exercise Training|Metformin|Statins|Angiotensin-Converting-Enzyme Inhibitor|Fasting, Intermittent|Angiotensin Hypertension
Interventions: DRUG: EXERCISE TRAINING WITH OR WITHOUT MEDICATION
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Occupational Distress in Doctors: The Effect of an Induction Programme
Status: COMPLETED
Conditions: Burnout, Professional|Anxiety|Grief|Adaptation, Psychological|Eating Behavior|Alcohol Drinking|Drug Use
Interventions: OTHER: Induction|OTHER: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Effects of Empagliflozin on Endogenous Glucose Production in End Stage Renal Disease(ESRD).
Status: COMPLETED
Conditions: End Stage Renal Disease
Interventions: COMBINATION_PRODUCT: Empagliflozin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Cognitive Behavioral Therapy Intervention for Internet Gaming Disorder
Status: UNKNOWN
Conditions: Internet Gaming Disorder
Interventions: BEHAVIORAL: Cognitive behavioral therapy|OTHER: Education material about IGD|OTHER: Education material about CBT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Glucocorticoids Plus Rituximab Compared to Glucocorticoids Plus Placebo for the Treatment of Patients With Newly-Diagnosed or Relapsing IgA Vasculitis
Status: RECRUITING
Conditions: IgA Vasculitis
Interventions: DRUG: Rituximab Injection|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of the APTIMA® HPV Assay and Comparison With the HR HC2® Test Using LBC ThinPrep® Specimens
Status: COMPLETED
Conditions: Human Papilloma Virus Infection
Interventions: OTHER: Thinprep® LBC|OTHER: APTIMA® HPV Assay|OTHER: HR HC2® HPV DNA|OTHER: Colposcopy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Pharmacokinetics Study of Multiple Ascending Doses of VV116 in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: VV116 200 mg Group|DRUG: VV116 400mg Group|DRUG: VV116 600mg Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prevalence of COVID-19 (Coronavirus Disease 19) in Pregnant Women on Labor in a Public Hospital in Chile (COroNavirus diSease Covid-19 pandEmic iN ChilE)
Status: COMPLETED
Conditions: Pregnancy|Covid19|Labor (Obstetrics)--Complications|Demography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: An Investigational Immunotherapy Study of Nivolumab in Combination With Rucaparib, Docetaxel, or Enzalutamide in Metastatic Castration-resistant Prostate Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Cancer
Interventions: BIOLOGICAL: nivolumab|DRUG: docetaxel|DRUG: enzalutamide|DRUG: rucaparib|DRUG: prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Duloxetine vs. Placebo in the Treatment of Osteoarthritis Knee Pain
Status: COMPLETED
Conditions: Osteoarthritis Knee Pain
Interventions: DRUG: Duloxetine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Whole Body Diffusion MRI for Non-invasive Lesion Detection and Therapy Follow-up: Study With Patients With Gastro-intestinal Tumors
Status: UNKNOWN
Conditions: Gastro-intestinal Tumor|Accurate Staging|Whole-body Diffusion Weighted MRI|Non-invasive
Interventions: PROCEDURE: Whole body diffusion MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: An Exploratory Clinical Study of Anti-CD19 CAR NK Cell (KN5501) in the Treatment of Relapsed/Refractory Immune Nephropathy
Status: RECRUITING
Conditions: Nephropathy
Interventions: DRUG: KN5501
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hepcidine and Iron Deficiency in Critically Ill Patients
Status: COMPLETED
Conditions: Anemia|Critical Illness|Hospitalized for 5 Days or More
Interventions: BIOLOGICAL: hepcidin|BIOLOGICAL: ferritin and transferrin saturation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Enfortumab Vedotin Schedule De-escalation in Metastatic Urothelial Carcinoma
Status: RECRUITING
Conditions: Urothelial Carcinoma|Metastatic Urothelial Carcinoma|Locally Advanced Urothelial Carcinoma
Interventions: DRUG: Enfortumab vedotin|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Diet Versus Sleeve Gastrectomy and Gastric Bypass on Appetite
Status: COMPLETED
Conditions: Obesity
Interventions: DIETARY_SUPPLEMENT: VLED group|PROCEDURE: Sleeve Gastrectomy group|PROCEDURE: Gastric Bypass group
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HAIC Plus Toripalimab vs. HAIC Plus Sorafenib for HCC With PVTT: a Non-comparative, Prospective, Randomized Trial
Status: RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: PROCEDURE: Hepatic arterial infusion chemotherapy|DRUG: Toripalimab|DRUG: Sorafenib|DRUG: systemic treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Middle Cerebral and Umbilical Arteries Doppler Indices in the Prediction of Adverse Neonatal Outcome Among Diabetic Pregnant Women
Status: UNKNOWN
Conditions: Diabetes Mellitus, Type 1
Interventions: DIAGNOSTIC_TEST: umbilical and middle cerebral artery Doppler
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Muscle Glycogen Synthesis When Caffeine and Protein is Co-Ingested With Carbohydrates
Status: COMPLETED
Conditions: Exercise Recovery
Interventions: DIETARY_SUPPLEMENT: Carbohydrate|DIETARY_SUPPLEMENT: Carbohydrate and protein ingestion|DIETARY_SUPPLEMENT: Carbohydrate and caffeine ingestion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Blood Pressure and Metabolic Effects of Nebivolol in Hypertensive Patients With Impaired Glucose Tolerance or Impaired Fasting Glucose
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Nebivolol with concomitant losartan or lisinopril|DRUG: HCTZ with concomitant losartan or lisinopril|DRUG: Placebo with concomitant losartan or lisinopril
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Aqueous Dynamics and Glaucoma Surgeries
Status: UNKNOWN
Conditions: Glaucoma|Ocular Hypertension
Interventions: DEVICE: HiFU|DEVICE: Baerveldt implant|DEVICE: Ahmed implant|DEVICE: STARflo|DEVICE: Hydrus Microstent implant|DEVICE: iStent implant|DEVICE: Kahook Dual Blade
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical Effectiveness of the "PICU Up!" Multifaceted Early Mobility Intervention for Critically Ill Children
Status: RECRUITING
Conditions: Child|Intensive Care Unit Acquired Weakness|Critical Illness|Hospital Acquired Pressure Ulcer
Interventions: OTHER: PICU Up!
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Treatment of Pregnancy RA
Status: UNKNOWN
Conditions: Rheumatoid Arthritis|Pregnancy Related
Interventions: DRUG: Certolizumab Pegol 200 MG/ML [Cimzia]|DRUG: Hydroxychloroquine|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Two-Part Study to Assess the Safety, Tolerability, PK and PD of ONO-7684 in Healthy Adult Volunteers
Status: COMPLETED
Conditions: Venous Thromboembolism
Interventions: DRUG: ONO-7684|DRUG: ONO-7684 Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of an Automated Insulin Delivery System in Participants With Type 1 Diabetes Mellitus (T1DM)
Status: COMPLETED
Conditions: Type1 Diabetes Mellitus
Interventions: DEVICE: AID System|DRUG: Insulin Lispro
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Concomitant Intraperitoneal and Systemic Chemotherapy in Patients With Extensive Peritoneal Carcinomatosis of Gastric Origin
Status: RECRUITING
Conditions: Gastric Cancer|Peritoneal Metastases
Interventions: DRUG: Irinotecan|DRUG: CAPOX
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vital Signs Changes During Dental Procedures
Status: COMPLETED
Conditions: Vital Signs Changes During Dental Procedures
Interventions: PROCEDURE: Scaling without LA|PROCEDURE: Simple restoration under LA|PROCEDURE: Simple exodontia under LA
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: A Study to Evaluate the Efficacy of Sage-217 in the Treatment of Adult Participants With Major Depressive Disorder (MDD)
Status: COMPLETED
Conditions: Depressive Disorder, Major
Interventions: DRUG: SAGE-217|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Influence of Neostigmine vs. Sugammadex on PORC and PPCs by Ultrasonography
Status: UNKNOWN
Conditions: Postoperative Pulmonary Complications
Interventions: DRUG: sugammadex as reversal drugs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Lumbar Puncture in Emergency Under Nitrous OXide
Status: UNKNOWN
Conditions: Pain|Anxiety
Interventions: DRUG: Fixed 50:50 mixture of nitrous oxide and oxygen|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: HIgh Power Short Duration Radiofrequency Ablation or Cryoballoon Ablation for Paroxysmal Atrial Fibrillation
Status: UNKNOWN
Conditions: Atrial Fibrillation and Flutter|Atrial Fibrillation|Paroxysmal Atrial Fibrillation
Interventions: PROCEDURE: Ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial of Chidamide Combined With Etoposide in Relapsed or Refractory NK/T-cell Lymphoma
Status: UNKNOWN
Conditions: NK/T-Cell Lymphoma
Interventions: DRUG: Chidamide+ Etoposide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Cottonseed Oil on Oxidative Stress, Inflammation, and Metabolism
Status: COMPLETED
Conditions: Inflammation|Healthy|Oxidative Stress|Metabolic Syndrome
Interventions: BEHAVIORAL: High dose CSO|BEHAVIORAL: Low dose CSO|BEHAVIORAL: Low dose OO|BEHAVIORAL: High dose OO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Possibilities of Interpreting the Night-to-Day Ratio Specified by 24-hour Blood Pressure Monitoring
Status: COMPLETED
Conditions: Cardiovascular Diseases
Interventions: OTHER: Ambulatory blood pressure monitoring|OTHER: Combined aerobic-resistance exercise|OTHER: The cardiovascular exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: iNOPulse for COVID-19
Status: WITHDRAWN
Conditions: COVID-19|Hypoxemia|Hypoxemic Respiratory Failure
Interventions: DRUG: Inhaled nitric oxide (iNO)|DRUG: Nitrogen gas|DRUG: Oxygen gas
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study for Epidemiology and Characterization of Myelodysplastic Syndromes (MDS) and Juvenile Myelomonocytic Leucemia (JMML) in Childhood
Status: ACTIVE_NOT_RECRUITING
Conditions: Myelodysplastic Syndromes|Juvenile Myelomonocytic Leukemia
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Everolimus and Docetaxel in Treating Patients With Recurrent, Locally Advanced, or Metastatic Head and Neck Cancer
Status: TERMINATED
Conditions: Head and Neck Cancer
Interventions: DRUG: docetaxel|DRUG: everolimus|OTHER: laboratory biomarker analysis|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: N-Acetylcysteine for Patients With COPD and Chronic Bronchitis
Status: TERMINATED
Conditions: COPD|Chronic Bronchitis
Interventions: DRUG: N-Acetylcysteine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: High-flow Nasal Oxygen Therapy to Prevent Extubation Failure in Adult Trauma Intensive Care Patients
Status: RECRUITING
Conditions: Intensive Care|Airway Extubation|Critical Care|Oxygen Therapy
Interventions: DEVICE: High flow nasal oxygen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: In-home Versus Hospital Preoperative Training for Patients Undergoing Total Knee Replacement
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: OTHER: Preoperative training (hospital)|OTHER: Preoperative training (home)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect on Adaptation to Cancer of Mobile Application Developed for Gynecological Cancer Patients
Status: COMPLETED
Conditions: Gynecologic Cancer|Chemotherapy Effect|Mobile Application|Physiological Adaptation|Psychosocial Adaptation
Interventions: BEHAVIORAL: A mobile application intervention developed for gynecological cancer patients receiving chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Acute Effect of Mirror Therapy on Rehabilitation of Paretic Upper Extremity After Chronic Stroke
Status: UNKNOWN
Conditions: Stroke
Interventions: OTHER: Mirror Therapy|OTHER: Control Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Improving the Referral of Patients With Chest Pain
Status: TERMINATED
Conditions: Acute Coronary Syndrome|Myocardial Infarction|Chest Pain
Interventions: DIAGNOSTIC_TEST: General Practitioner diagnosis with Heart score
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effects of Multi-day Interruptions in Sitting on Type 2 Diabetes-relevant Outcomes in Children
Status: RECRUITING
Conditions: Sedentary Behavior|Affect|Metabolic Disturbance|Anxiety|Cardiac Autonomic Nervous System Function
Interventions: BEHAVIORAL: SIT+WALK|BEHAVIORAL: EX
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Late Onset Postoperative Nausea and Vomiting
Status: COMPLETED
Conditions: Postoperative Nausea and Vomiting
Interventions: DRUG: Placebo|DRUG: Ondansetron, Dexamethasone|DRUG: Midazolam, dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION