pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Dehydroepiandrosterone Versus Growth Hormone in Women Undergoing ICSI With Expected Poor Ovarian Response
Status: UNKNOWN
Conditions: Subfertility
Interventions: DRUG: DHEA|DRUG: Growth Hormone-Releasing Hormone|DRUG: Placebo 1|DRUG: Placebo 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Vapocoolant Spray and Eutectic Mixture of Local Anesthetics in Reducing Pain From Spinal Injection
Status: COMPLETED
Conditions: Adult Patient Undergoing Elective Surgery With Spinal Anesthesia
Interventions: DRUG: Vapocoolant spray, EMLA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Nebulized PL for Post-COVID-19 Syndrome
Status: TERMINATED
Conditions: Covid19
Interventions: BIOLOGICAL: Nebulized Platelet Lysate|OTHER: Nebulized Sterile Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Radiographic and Intravascular (IVUS) Evaluation of Venous Morphology During CCSVI Treatment
Status: UNKNOWN
Conditions: To Determine the Safety and Validity of Venous Angioplasty and|Valvuloplasty in the Treatment of CCSVI. In Addition, it Will|Allow Researchers to Sub-classify Valve Morphology in Relation|to Treatment Success. This Will be Evidenced by Venous Patency|Forty-eight Hours by Doppler Ultrasound as Well as Clinical|Symptom Improvement.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Efficacy of PCI-32765 in Participants With Relapsed/Refractory Mantle Cell Lymphoma (MCL)
Status: COMPLETED
Conditions: Mantle Cell Lymphoma
Interventions: DRUG: PCI-32765
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Viability-Guided Angioplasty After Acute Myocardial Infarction-Trial (The VIAMI-Trial)
Status: UNKNOWN
Conditions: Myocardial Infarction|Coronary Artery Disease
Interventions: PROCEDURE: coronary balloon-angioplasty with stenting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: First-Line Gemcitabine, Cisplatin + Ipilimumab for Metastatic Urothelial Carcinoma
Status: COMPLETED
Conditions: Urothelial Carcinoma
Interventions: DRUG: Gemcitabine|DRUG: Cisplatin|DRUG: Ipilimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Tumor Tissue Samples From Patients With Stage I, Stage II, or Stage III Malignant Melanoma
Status: TERMINATED
Conditions: Melanoma (Skin)
Interventions: GENETIC: gene expression analysis|GENETIC: polymerase chain reaction|GENETIC: polymorphism analysis|OTHER: matrix-assisted laser desorption/ionization time of flight mass spectrometry|OTHER: medical chart review
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: PRophylaxis of Exposed COVID-19 Individuals With Mild Symptoms Using choloroquinE Compounds
Status: TERMINATED
Conditions: Sars-CoV2|Symptomatic Condition|Covid-19
Interventions: DRUG: Hydroxychloroquine Sulfate Regular dose|DRUG: Hydroxychloroquine Sulfate Loading Dose|DRUG: Chloroquine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Cognitive Exercises With Sensory Motor Relearning Program on Upper Limb Function in Sub-Acute Stroke Patients
Status: COMPLETED
Conditions: Stroke|Ischemic
Interventions: OTHER: Cognitive sensory motor relearning|OTHER: Sensory motor relearning|OTHER: Motor Relearning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Computational Modeling of 60 Hz Subthalamic Nucleus Deep Brain Stimulation for Gait Disorder in Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: DEVICE: Deep Brain Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: AADAPT - Analysis of Advagraf Dose Adaptation Post Transplantation
Status: COMPLETED
Conditions: Renal Transplantation
Interventions: DRUG: Advagraf Capsule|DRUG: Prograf Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 1b Study of PLX5622 in Rheumatoid Arthritis Patients Who Are Receiving Methotrexate
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: PLX5622|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Pirtobrutinib (LOXO-305) in Participants With Impaired Liver Function and Healthy Participants
Status: COMPLETED
Conditions: Healthy|Hepatic Insufficiency
Interventions: DRUG: Pirtobrutinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Online Social Learning Program for Parents With Irritable Bowel Syndrome: Raising Resilient Children
Status: RECRUITING
Conditions: Irritable Bowel Syndrome|Abdominal Pain
Interventions: BEHAVIORAL: Social Learning and Cognitive Behavioral Therapy (SLCBT)|BEHAVIORAL: Attention Education Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Dun Ye Guan Xin Ning Tablet in Patients With Stable Angina Pectoris
Status: UNKNOWN
Conditions: Coronary Heart Disease
Interventions: DRUG: Dun Ye Guan Xin Ning
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Study of EDG-5506 in Becker Muscular Dystrophy (GRAND CANYON)
Status: RECRUITING
Conditions: Becker Muscular Dystrophy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vaccine Therapy With or Without Interleukin-2 in Treating Patients With Locally Advanced or Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: BIOLOGICAL: aldesleukin|BIOLOGICAL: ras peptide cancer vaccine|PROCEDURE: adjuvant therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Comparison of TG-873870(Nemonoxacin) to Levofloxacin in Community-Acquired Pneumonia
Status: COMPLETED
Conditions: Community-Acquired Pneumonia
Interventions: DRUG: TG-873870(Nemonoxacin)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Rotator Cuff Repair Using Standard Double Row Technique With Platelet Rich Fibrin Membrane vs. Standard Double Row Technique
Status: COMPLETED
Conditions: Rotator Cuff Tear
Interventions: DEVICE: PRFM|PROCEDURE: Double Row
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Utility of a Smart Phone Application in Assessing Radial Artery Patency - the CAPITAL iRADIAL Study
Status: COMPLETED
Conditions: Coronary Heart Disease
Interventions: OTHER: Modified Allen Test|OTHER: Iphone artery assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Pilot Study of Losartan and N-acetylcysteine as Inhibitors of Muscle Oxidative Stress in Elderly
Status: COMPLETED
Conditions: Aging
Interventions: DRUG: N-acetylcysteine|DRUG: Losartan|DRUG: Placebo losartan|DRUG: Placebo N-acetylcysteine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study of Selinexor Plus Cytarabine and Idarubicin in Patients With Relapsed/Refractory Acute Myeloid Leukemia (AML)
Status: COMPLETED
Conditions: Acute Myeloid Leukemia (Relapsed/Refractory)
Interventions: DRUG: Selinexor|DRUG: Idarubicin|DRUG: Cytarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess Safety, Tolerability and Pharmacokinetics of XC221 in Healthy Volunteers
Status: COMPLETED
Conditions: Influenza|Acute Respiratory Infection
Interventions: DRUG: XC221 60 mg|DRUG: XC221 200 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Protein Nutrition for Muscle Hypertrophy in Older Adults
Status: COMPLETED
Conditions: Healthy Elderly Muscle|Anabolically Resistant Elderly Muscle
Interventions: DIETARY_SUPPLEMENT: isolated whey protein|DIETARY_SUPPLEMENT: micellar whey protein|DIETARY_SUPPLEMENT: glycine|DIETARY_SUPPLEMENT: citrulline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Recombinant Human Erythropoietin on Platelet Function in Patients With Acute Myocardial Infarction
Status: COMPLETED
Conditions: Myocardial Infarction
Interventions: DRUG: Recombinant human erythropoietin alfa (drug)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Safety and Activity of TRL345 in Healthy Volunteers
Status: RECRUITING
Conditions: Healthy Volunteers
Interventions: DRUG: TRL345, a human monoclonal antibody
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A 16 Week Study Evaluating the Introduction of a GMP Based Protein Substitute in Participants With PKU
Status: COMPLETED
Conditions: Phenylketonurias
Interventions: DIETARY_SUPPLEMENT: PKU Sphere
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Randomized Controlled Trial Between Laparoscopic and Open Surgery in Transverse and Descending Colon Cancer Patients
Status: UNKNOWN
Conditions: Malignant Neoplasm of Transverse Colon|Malignant Neoplasm of Descending Colon
Interventions: PROCEDURE: Open surgery|PROCEDURE: Laparoscopic surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Muscle Fatigability and Trip-specific Fall Risk in Adults With Knee Osteoarthritis
Status: RECRUITING
Conditions: Osteoarthritis, Knee
Interventions: BEHAVIORAL: 30 minute treadmill walk
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Seaweed, the Food Matrix, and Iodine Bioavailability
Status: UNKNOWN
Conditions: Iodine Bioavailability
Interventions: DIETARY_SUPPLEMENT: Pizza|DIETARY_SUPPLEMENT: Seaweed Sheets|DIETARY_SUPPLEMENT: Seaweed Powder|DIETARY_SUPPLEMENT: Potassium iodide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Computer-Based Weight Maintenance in Primary Care
Status: COMPLETED
Conditions: Body Weight|Weight Loss|Motor Activity
Interventions: BEHAVIORAL: 24 months of personalized coaching through the EHR patient portal, with 24 scheduled contacts.|BEHAVIORAL: Online self-monitoring|BEHAVIORAL: Real-time updates to Primary Care physicians
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Potassium Correction for RAAS Optimization in Chronic Kidney Disease
Status: RECRUITING
Conditions: Chronic Kidney Diseases|Hyperkalemia|Hypertension
Interventions: DRUG: Patiromer 8400 MG [Veltassa]|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of a High Density Formula on Growth and Safety in Congenital Heart Disease Infants
Status: COMPLETED
Conditions: Congenital Heart Disease
Interventions: DIETARY_SUPPLEMENT: normal density formula (Necocate)|DIETARY_SUPPLEMENT: high density formula(Infatrini)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Combination Chemotherapy and Rituximab in Treating Patients With Newly Diagnosed Burkitt's Lymphoma or Leukemia
Status: COMPLETED
Conditions: Leukemia|Lymphoma
Interventions: BIOLOGICAL: Filgrastim|BIOLOGICAL: Rituximab|DRUG: Cyclophosphamide|DRUG: Cytarabine|DRUG: Methotrexate|DRUG: Prednisone|DRUG: Hydrocortisone|DRUG: Vincristine|DRUG: Leucovorin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tislelizumab Monotherapy Versus Salvage Chemotherapy for Relapsed/Refractory Classical Hodgkin Lymphoma
Status: RECRUITING
Conditions: Classical Hodgkin Lymphoma
Interventions: DRUG: Tislelizumab|DRUG: Salvage Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Research Study to Evaluate Selegiline in the Treatment of Borderline Personality Disorder
Status: COMPLETED
Conditions: Borderline Personality Disorder
Interventions: DRUG: Selegiline|DRUG: Placebo (for Selegiline)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Ontamalimab as Maintenance Treatment in Participants With Moderate to Severe Crohn's Disease (CARMEN CD 307)
Status: TERMINATED
Conditions: Crohn's Disease
Interventions: DRUG: Ontamalimab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Carbohydrate-protein Co-ingestion on Short-term Recovery
Status: COMPLETED
Conditions: Dietary Supplementations
Interventions: DIETARY_SUPPLEMENT: Carbohydrate|DIETARY_SUPPLEMENT: Carbohydrate-Protein|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: The Use of Melatonin for Delirium Prevention in Medically Hospitalized Patients
Status: NOT_YET_RECRUITING
Conditions: Delirium
Interventions: DRUG: Intervention 1|DRUG: Intervention 2|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Radiotherapy Combined With Realgar-Indigo Naturalis Formula (RIF) in the Treatment of Rhabdomyosarcoma(RMS) in Children
Status: NOT_YET_RECRUITING
Conditions: Rhabdomyosarcoma, Child
Interventions: DRUG: Realgar-Indigo Naturalis Formulation|RADIATION: Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Study of Abiraterone Acetate Tablets (I) or ZYTIGA® in Patients With Metastatic Castration-resistant Prostate Cancer
Status: COMPLETED
Conditions: Metastatic Castration-resistant Prostate Cancer (mCRPC)
Interventions: DRUG: Abiraterone Acetate Tablets (I)|DRUG: ZYTIGA®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Feasibility of Radioembolization Using Ho-166 in Patients With Unresectable Hepatocellular Carcinoma
Status: COMPLETED
Conditions: Hepatocellular Carcinoma
Interventions: RADIATION: Radioembolization using Holmium-166
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Haploidentical PBMC Transplant for Severe Congenital Anemias
Status: ACTIVE_NOT_RECRUITING
Conditions: Sickle Cell Anemia
Interventions: PROCEDURE: PBSC Transplant|DRUG: Alemtuzumab|DRUG: Sirolimus|DRUG: Cyclophosphamide|PROCEDURE: Low Dose Irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of a Therapy Without Drugs, Supplementary to an Usual Treatment for the Pains Caused by Removing the Redon's Drain From a 7 to 17 Years Old Child in Pediatric Surgery.
Status: COMPLETED
Conditions: Surgical Operation With the Settle of a Redon's Drain
Interventions: OTHER: Relaxing-touch method
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Repeat BCG Vaccinations For The Treatment Of Pediatric Type 1 Diabetes
Status: RECRUITING
Conditions: Diabetes Mellitus, Type 1|Diabetes type1|Autoimmune Diabetes
Interventions: BIOLOGICAL: Bacillus Calmette-Guérin|BIOLOGICAL: Saline Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety of Sanofi Pasteur's Combined Vaccine Given as a Three-Dose Primary Series at 2, 3,4 Months of Age and Followed by a Booster Dose Given at 16 to 17 Months of Age in Vietnamese Infants Who Previously Received a Dose of Hepatitis B Vaccine at Birth or Within 1 Week After Birth
Status: COMPLETED
Conditions: Diphtheria|Tetanus|Pertussis|Poliomyelitis|Hepatitis B|Haemophilus Influenzae Type b
Interventions: BIOLOGICAL: Hexaxim®
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Inspiratory Muscle Training and Expiratory Muscle Thickness
Status: COMPLETED
Conditions: Intensive Care Unit Syndrome|Muscle Weakness|Rehabilitation
Interventions: OTHER: conventional physiotherapy+ IMT|OTHER: conventional physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase Ib Study of Anetumab Ravtansine in Combination With Pemetrexed and Cisplatin in Mesothelin-expressing Solid Tumors
Status: COMPLETED
Conditions: Medical Oncology
Interventions: DRUG: BAY 94-9343|DRUG: Pemetrexed|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study to Explore Combination of Gefitinib (ZD1839, Iressa) and Radiotherapy in Non-Metastatic Prostate Cancer
Status: COMPLETED
Conditions: Non-Metastatic Prostate Cancer
Interventions: DRUG: Gefitinib, radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: "Surgical vs. Non-surgical Peri-implant Therapy"
Status: UNKNOWN
Conditions: Peri-Implantitis|Implant Complication|Bone Loss
Interventions: PROCEDURE: Surgical therapy|PROCEDURE: Non-surgical therapy of peri-implantitis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Autonomic Nervous System Role in Uncontrolled ASTHMA and the Paucigranulocitic Phenotype
Status: COMPLETED
Conditions: Asthma
Interventions: DEVICE: EKG (electrocardiogram)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pain Control Without Opioids
Status: WITHDRAWN
Conditions: Perioperative Pain
Interventions: DRUG: Ibuprofen 600 mg|DRUG: OxyCODONE 5 Mg Oral Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Low-grade Inflammation and Gut Symptoms From A2 and Hydrolyses A1 Milk
Status: COMPLETED
Conditions: Milk Intolerance
Interventions: OTHER: Dietary intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Decreasing Unnecessary Antibiotics Prescribed for Possible Pneumonia Despite Normal Respiratory Rate and Oxygenation
Status: ENROLLING_BY_INVITATION
Conditions: Pneumonia
Interventions: BEHAVIORAL: Antibiotic stewardship messaging
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effect of Adding Dexamethasone to 2% Lidocaine
Status: COMPLETED
Conditions: Pulpitis - Irreversible
Interventions: DRUG: Lidocaine Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Prospective, Randomized, Controlled Study of rhTPO in Combination With Herombopag + CsA vs Herombopag + CsA for the Treatment of Primary TD-NSAA
Status: NOT_YET_RECRUITING
Conditions: Aplastic Anemia|Drug Effect
Interventions: DRUG: Herombopag + CsA|DRUG: rhTPO combined with Herombopag + CsA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Surface NeuroMuscular Electrical Stimulation in the Treatment of Chronic Venous Leg Ulcers
Status: COMPLETED
Conditions: Chronic Venous Disease
Interventions: DEVICE: VASGARD stimulator|OTHER: Compression bandaging
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Massage Therapy and Kinesthetic Stimulation on Pre-Term Infants
Status: COMPLETED
Conditions: Prematurity
Interventions: BEHAVIORAL: Massage therapy without exercise|BEHAVIORAL: Massage therapy with exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Mobilization of Stem Cells With AMD3100 (Plerixafor) and G-CSF in Non-Hodgkin's Lymphoma and Multiple Myeloma Patients
Status: COMPLETED
Conditions: Lymphoma, Non-Hodgkin|Multiple Myeloma
Interventions: DRUG: G-CSF Plus Plerixafor
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Skate Skin Extract on Cognitive Function in Adults
Status: COMPLETED
Conditions: Subjective Memory Impairment
Interventions: DIETARY_SUPPLEMENT: Skate group|DIETARY_SUPPLEMENT: Placebo group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Genome Sequencing Strategies for Genetics Diagnosis of Patients With Intellectual Disability
Status: ACTIVE_NOT_RECRUITING
Conditions: Intellectual Disability
Interventions: GENETIC: Trio Whole Genome Sequencing|GENETIC: Simplex Whole Genome Sequencing|GENETIC: Current French Reference strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Randomized, Controlled Study to Evaluate Algisyl-LVR™ as a Method of Left Ventricular Augmentation for Heart Failure
Status: COMPLETED
Conditions: Heart Failure|Dilated Cardiomyopathy
Interventions: DEVICE: Algisyl-LVR|DRUG: Standard medical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of KW-136 and Sofosbuvir for Treatment of Chronic Hepatitis C
Status: COMPLETED
Conditions: Hepatitis C, Chronic
Interventions: DRUG: KW-136|DRUG: Sofosbuvir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rationale, Design and Methods for the Early Surgery in Infective Endocarditis Study (ENDOVAL)
Status: UNKNOWN
Conditions: Infective Endocarditis
Interventions: PROCEDURE: Cardiac surgery|PROCEDURE: State-to-the-art treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study for Characterisation of Predictive Parameters of Clonal Evolution in Subjects With GATA2 Germline Mutation
Status: RECRUITING
Conditions: GATA2 Gene Mutation
Interventions: OTHER: Biological samples (blood and bone marrow samples).
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Chemotherapy and Radiation Therapy in Treating Patients With Stage II or Stage III Bladder Cancer That Was Removed by Surgery
Status: COMPLETED
Conditions: Bladder Cancer
Interventions: DRUG: induction cisplatin|DRUG: induction 5-fluorouracil|DRUG: induction gemcitabine|RADIATION: Induction BID radiation therapy|RADIATION: Induction QD radiation therapy|RADIATION: Consolidation BID radiation therapy|RADIATION: Consolidation QD radiation therapy|DRUG: consolidation gemcitabine|DRUG: consolidation 5-fluorouracil|DRUG: consolidation cisplatin|PROCEDURE: radical cystectomy|PROCEDURE: Post-Induction Chemoradiotherapy Endoscopic Response Evaluation|DRUG: adjuvant gemcitabine|DRUG: adjuvant cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Patient-Controlled Analgesia With Different Background Infusion
Status: COMPLETED
Conditions: Patient-Controlled Analgesia
Interventions: DEVICE: Patient-Controlled Analgesia(PCA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Centella Asiatica in Older Adults
Status: NOT_YET_RECRUITING
Conditions: Endothelial Dysfunction
Interventions: DIETARY_SUPPLEMENT: Centella Asiatica|DIETARY_SUPPLEMENT: Placebo Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Study to Evaluate the Safety of bb2121 in Subjects With High Risk, Newly Diagnosed Multiple Myeloma (NDMM)
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: BIOLOGICAL: bb2121|DRUG: Fludarabine|DRUG: Cyclophosphamide|DRUG: Lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy, Safety and Tolerability of Oral LPCN 1144 in Subjects With Nonalcoholic Steatohepatitis
Status: COMPLETED
Conditions: Nonalcoholic Steatohepatitis (NASH)
Interventions: DRUG: LPCN 1144 Formulation A|DRUG: LPCN 1144 Formulation B|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Safety and Tolerability of Long-term TEV-50717 (Deutetrabenazine) for Treatment of Tourette Syndrome in Children and Adolescents
Status: TERMINATED
Conditions: Tourette Syndrome
Interventions: DRUG: TEV-50717|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial of Bare Metal Stent - Cobalt Chromium Versus Stent Coating With Sirolimus
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DEVICE: DRUG ELUTING STENT|DEVICE: BARE METAL STENT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of IV Iron in Patients With Heart Failure With Preserved Ejection Fraction
Status: COMPLETED
Conditions: Iron-deficiency|Heart Failure
Interventions: DRUG: Ferric Carboxymaltose 50Mg/Ml Inj 15Ml|DRUG: Saline Solution for Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Silicone Gel Versus Contractubex Phonophoresis for Post-burn Hypertrophic Scars
Status: COMPLETED
Conditions: Hypertrophic Scar
Interventions: COMBINATION_PRODUCT: phonophoresis with different material
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Remineralizing Efficacy of Giomer Varnish vs. Fluoride Varnish in Management of White Spot Lesions in Adult Patients
Status: UNKNOWN
Conditions: Caries, Dental|Remineralization|White Spot Lesion
Interventions: DRUG: Bio-smart Light Cured Protective Shield with bioactive S-PRG (Surface Pre- Reacted Glass ionomer) filler technology (PRG Barrier Coat) by (By SHOFU Inc., Japan).
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Deep rTMS (H-coil) for Neuropathic Pain or Fibromyalgia
Status: RECRUITING
Conditions: Neuropathic Pain|Fibromyalgia
Interventions: DEVICE: Deep active rTMS with Hesed coil|DEVICE: Sham rTMS with Hesed coil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Of FOLFIRI Chemotherapy With Or Without Sunitinib In Patients With Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: 5 fluorouracil|DRUG: irinotecan|DRUG: levo- leucovorin|DRUG: sunitinib|DRUG: 5 fluorouracil|DRUG: irinotecan|DRUG: levo- leucovorin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Glimepiride vs Metformin as Monotherapy in Pediatric Subjects With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: glimepiride|DRUG: metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Randomized Trial for Botox Urinary Incontinence
Status: COMPLETED
Conditions: Urinary Incontinence
Interventions: OTHER: Bladder diary|OTHER: Questionnaires|PROCEDURE: Urodynamics|OTHER: Pad weight
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Posterior Segment Intrusion Using Miniplates
Status: UNKNOWN
Conditions: Orthodontic Anchorage Procedures
Interventions: DEVICE: mini-plates supported molar intrusion|PROCEDURE: Application of ULTRACARE benzocaine 20%,|PROCEDURE: Administration of , Mepivacaine-l|PROCEDURE: BETADINE povidone-iodine 10%|DRUG: (150g Clindamycin/tds) for 1 week|DRUG: (Cataflam 25mg), are prescribed post-operatively
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Catheter Ablation on Clinical Course of Migraine in AF Patients With or Without Previous History of Migraine
Status: COMPLETED
Conditions: Migraine|Atrial Fibrillation
Interventions: PROCEDURE: Radiofrequency catheter ablation|PROCEDURE: Radiofrequency catheter ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Use of Oral Omeprazole and Intravenous Pantoprazole in Patients With Hypersecretion of Gastric Acid
Status: COMPLETED
Conditions: Gastrinoma|Zollinger Ellison Syndrome
Interventions: DRUG: Pantoprazole|DRUG: Omeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: [18F]FTT Positron Emission Tomography for the Measurement of PARP Tumor Expression in Patients With Metastatic Breast Cancer
Status: NOT_YET_RECRUITING
Conditions: Anatomic Stage IV Breast Cancer AJCC v8|Metastatic Breast Carcinoma
Interventions: OTHER: Best Practice|PROCEDURE: Biopsy of Breast|PROCEDURE: Computed Tomography|OTHER: Electronic Health Record Review|OTHER: Fludeoxyglucose F-18|RADIATION: Fluorine F 18 Fluorthanatrace|DRUG: Immune Checkpoint Inhibitor|DRUG: Poly (ADP-Ribose) Polymerase Inhibitor|PROCEDURE: Positron Emission Tomography|PROCEDURE: Positron Emission Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparison of Two Periarticular Injection Medications for Adjunctive Pain Management Following Total Knee Arthroplasty (TKA)
Status: UNKNOWN
Conditions: Total Knee Arthroplasty
Interventions: DRUG: Exparel|DRUG: Marcaine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose:
Clinical trial: Global Study to Assess the Safety and Effectiveness of Edoxaban (DU-176b) vs Standard Practice of Dosing With Warfarin in Patients With Atrial Fibrillation
Status: COMPLETED
Conditions: Stroke|Atrial Fibrillation|Embolism
Interventions: DRUG: warfarin tablets|DRUG: Edoxaban tablets (high dose regimen-60mg)|DRUG: Edoxaban tablets (low dose regimen-30mg)|DRUG: placebo warfarin|DRUG: placebo edoxaban
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Screening, Motivational Assessment, Referral, and Treatment in Emergency Departments
Status: COMPLETED
Conditions: Drug Abuse
Interventions: BEHAVIORAL: screening|BEHAVIORAL: assessment|BEHAVIORAL: referral|BEHAVIORAL: Brief intervention|BEHAVIORAL: booster sessions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Program on Lung Cancer Screening and Tobacco Cessation
Status: COMPLETED
Conditions: Smoking
Interventions: BEHAVIORAL: TLC monthly|BEHAVIORAL: TLC quarterly|BEHAVIORAL: MTM|BEHAVIORAL: 4 week assessment|BEHAVIORAL: 8 week assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Clinical Performance of Reinforced Glass Ionomer Restorations
Status: COMPLETED
Conditions: Dental Caries
Interventions: OTHER: Equia Forte Fil|OTHER: Zirconomer Improved
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transcranial Direct Current Stimulation (tDCS) in Vasomotor Symptoms of Menopause
Status: COMPLETED
Conditions: Hot Flashes
Interventions: PROCEDURE: Transcranial Direct Current Stimulation|PROCEDURE: Sham Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Behavioral Alcohol Responses (BAR) Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Alcohol Drinking|Alcohol Use Disorder|Alcohol Intoxication|Alcohol; Harmful Use|Alcoholism|Binge Drinking
Interventions: DRUG: Alcohol|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Ephedrine, Phenylephrine and Metaraminol Effects on Maternal Cardiac Output, Uterine Blood Flow and Fetal Circulation
Status: UNKNOWN
Conditions: Preeclampsia
Interventions: DRUG: Ephedrine|DRUG: Phenylephrine|DRUG: Metaraminol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Middle Meningeal Artery Embolization for the Treatment of Subdural Hematomas With TRUFILL® n-BCA
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Subdural Hematoma
Interventions: DEVICE: Experimental: Interventional Cohort: Treatment Arm|OTHER: Active Comparator: Interventional Cohort: Control Arm|DEVICE: Experimental: Observational Cohort: Treatment Arm|OTHER: Active Comparator: Observational Cohort: Control Arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Influence of Esophageal Washout on Local Carcinoma Recurrence After Curative Resection
Status: COMPLETED
Conditions: Esophageal Neoplasms
Interventions: DRUG: Povidone-Iodine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of Oral Ibrexafungerp (SCY-078) vs. Placebo in Subjects With Acute Vulvovaginal Candidiasis (VANISH 303)
Status: COMPLETED
Conditions: Candida Vulvovaginitis
Interventions: DRUG: Ibrexafungerp|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Effect of Osteo Introducer System in Total Hip Arthroplasty
Status: COMPLETED
Conditions: Joint Disease
Interventions: PROCEDURE: Minimum invasive total hip arthroplasty|PROCEDURE: Common total hip arthroplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinic-based Nasopharyngoesophagogastroscopy Following Bariatric Surgery
Status: WITHDRAWN
Conditions: Obesity
Interventions: PROCEDURE: clinic-based nasopharyngoendoscopy|PROCEDURE: Standard Endoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Manuel Therapy on Tonus, Proprioseption and Balance in Multiple Sclerosis
Status: COMPLETED
Conditions: Postural Balance|Multiple Sclerosis|Cervical Region Disorder Nos|Muscle Tonus|Proprioception
Interventions: OTHER: classic rehabilitation|OTHER: classic rehabilitation+mobilization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Proton Pump Inhibitor Plus Propranolol Versus Proton Pump Inhibitor Alone on Peptic Ulcer Healing in Patients With Liver Cirrhosis
Status: TERMINATED
Conditions: Liver Cirrhosis|Peptic Ulcer
Interventions: DRUG: Proton-pump inhibitor|DRUG: Propranolol+Proton-pump inhibitor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CAD-EYE System for the Detection of Neoplastic Lesions in Patients With Lynch Syndrome
Status: NOT_YET_RECRUITING
Conditions: Lynch Syndrome
Interventions: DEVICE: Colorectal cancer screening with CAD EYE colonoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Vaccine Therapy in Treating Patients With Epstein-Barr Virus-Related Cancer
Status: COMPLETED
Conditions: Gastric Cancer|Head and Neck Cancer|Lymphoma|Lymphoproliferative Disorder|Nonneoplastic Condition
Interventions: BIOLOGICAL: EBNA1 C-terminal/LMP2 chimeric protein-expressing recombinant modified vaccinia Ankara vaccine|OTHER: laboratory biomarker analysis|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: A Study of KW-6356 in Subjects With Early Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DRUG: KW-6356|DRUG: KW-6356|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I/II Randomized Study of Stereotactic Ablative Radiotherapy (SABR) Versus Standard of Care for Refractory Structural Cardiac Arrhythmias (SABR-HEART)
Status: WITHDRAWN
Conditions: Cardiac Arrhythmia|Cardiac|Ventricular Tachyarrhythmias
Interventions: DEVICE: stereotactic ablative radiotherapy (SABR)|OTHER: Standard of Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics and Safety Between "DWJ1421" and "DWC201903" in Healthy Male Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: DWJ1421|DRUG: DWC201903
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Compare Pharmacokinetics and Pharmacodynamics of IPX066 to Standard Carbidopa-Levodopa
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DRUG: IPX066|DRUG: IR CD-LD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Tumor Treating Fields (TTFields, 150 kHz) as Front-Line Treatment of Locally-advanced Pancreatic Adenocarcinoma Concomitant With Gemcitabine and Nab-paclitaxel (PANOVA-3)
Status: ACTIVE_NOT_RECRUITING
Conditions: Pancreas Adenocarcinoma
Interventions: DEVICE: NovoTTF-200T|DRUG: Gemcitabine|DRUG: nab paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of CC-90001 in Subjects With Idiopathic Pulmonary Fibrosis
Status: TERMINATED
Conditions: Idiopathic Pulmonary Fibrosis|Fibrosis|Idiopathic Interstitial Pneumonias|Pathologic Processes|Lung Diseases, Interstitial|Lung Diseases|Respiratory Tract Diseases
Interventions: DRUG: CC-90001|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Repurposing a Histamine Antagonist to Benefit Patients With Pulmonary Hypertension
Status: COMPLETED
Conditions: Pulmonary Arterial Hypertension|Right Heart Failure
Interventions: DRUG: Famotidine 20 MG|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Opioids With or Without Olanzapine in Treating Patients With Moderate to Severe Cancer Pain
Status: WITHDRAWN
Conditions: Hematopoietic/Lymphoid Cancer|Pain|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: olanzapine|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Investigation of 1.2% Sodium Hyaluronate for Treatment of Painful Chronic Osteoarthritis of the Knee
Status: COMPLETED
Conditions: Osteoarthritis of the Knee
Interventions: DEVICE: 1.2% Sodium Hyaluronate|DEVICE: Buffered Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of FAST PV and mGFR Technology™
Status: COMPLETED
Conditions: Kidney Diseases|Renal Insufficiency, Chronic|Acute Kidney Injury|Urologic Diseases|Renal Insufficiency
Interventions: DEVICE: VFI|DEVICE: Iohexol
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Duration of Sciatic Nerve Block After Injection of Local Anesthetic In or Around the Nerve
Status: COMPLETED
Conditions: Orthopedic Surgical Procedures|Postoperative Pain
Interventions: PROCEDURE: Intraneural Injection for Subgluteal Sciatic Nerve Block|PROCEDURE: Perineural Injection for Subgluteal Sciatic Nerve Block|PROCEDURE: Femoral Nerve Block|PROCEDURE: Patient-controlled postoperative analgesia|DRUG: Mepivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, PK and Efficacy of AZD1152 in Patients With Relapsed Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Myeloid Leukemia
Interventions: DRUG: AZD1152
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neuroprotective Goal Directed Hemodynamic Optimization in Post-cardiac Arrest Patients
Status: COMPLETED
Conditions: Cerebral Ischemia|Cardiac Arrest
Interventions: OTHER: Neuroprotective goal directed hemodynamic optimization|OTHER: MAP > 65mmHg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 3 Study to Evaluate the Efficacy and Safety of CLS006 Versus Vehicle in Subjects 2 Years of Age or Older With Cutaneous Common Warts
Status: COMPLETED
Conditions: Cutaneous Common Warts
Interventions: DRUG: CLS006 (Furosemide) Topical Gel|DRUG: Vehicle Topical Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT