pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Icotinib With Concurrent Radiotherapy Versus Chemotherapy With Concurrent Radiotherapy in Non-small Cell Lung Cancer
Status: UNKNOWN
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: Icotinib with concurrent radiotherapy|DRUG: Chemoradiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Urgent vs. Early Endoscopy in High Risk Patients With Upper Gastrointestinal Bleeding (UGIB)
Status: COMPLETED
Conditions: Bleeding Peptic Ulcer|Active Bleeding|Gastrointestinal Bleeding
Interventions: OTHER: Urgent endoscopy|OTHER: Early endoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Bioavailability and Tolerability of Fexofenadine Hydrochloride Topical Lotion 1%
Status: COMPLETED
Conditions: Atopic Dermatitis|Atopic Dermatitis Eczema|Atopic Rash|Rash|Pruritus|Urticaria|Urticaria Chronic|Psoriasis|Psoriasis Vulgaris|Skin Rash|Skin Inflammation|Eczema
Interventions: DRUG: Fexofenadine Hydrochloride Topical Lotion 1% (OP2101)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Chemoradiotherapy in Oesophageal Cancer Including PET Response and Dose Escalation
Status: UNKNOWN
Conditions: Oesophageal Cancer
Interventions: DRUG: Carboplatin|DRUG: Paclitaxel|DRUG: Cisplatin|DRUG: Capecitabine|RADIATION: Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of PegInterferon-Ribavirin-Boceprevir Therapy in Patients Infected With G1 HCV With Cirrhosis, Awaiting Liver Transplantation
Status: COMPLETED
Conditions: HCV Infection|Liver Cirrhosis, Experimental
Interventions: DRUG: Boceprevir|BIOLOGICAL: Peg-Interferon α-2b or Peg-Interferon α-2a|DRUG: Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Mobile Application on Hypothyroid Patients
Status: RECRUITING
Conditions: Hypothyroidism|Symptom Management|Symptoms and Signs|Mobile Application|Digital Health
Interventions: OTHER: Mobile application with symptom management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Treatment of High-Risk Cerebral Primitive Neuroectodermal Tumors in Children Aged Over 5 Years
Status: COMPLETED
Conditions: Metastatic, Cerebral Primitive Neuroectodermal Tumors
Interventions: DRUG: Chemotherapy (carboplatin, etoposide, thiotepa)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: M-Health Care for Patients After AMI on Disease Perception, Self-Efficacy, Anxiety and Cardio-Respiratory Fitness
Status: COMPLETED
Conditions: Mobile Health|Acute Myocardial Infarction|Undefined|Self-efficacy|Anxiety|Cardio-respiratory Fitness
Interventions: COMBINATION_PRODUCT: M-Health
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Long-term Outcomes After Laparoscopic Subtotal and Total Hysterectomy
Status: NOT_YET_RECRUITING
Conditions: Hysterectomy
Interventions: PROCEDURE: Subtotal Laparoscopic Hysterectomy|PROCEDURE: Total Laparoscopic Hysterectomy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of the Efficacy of Bio-K+ Cl-1285® In the Nasal Decolonization of Methicillin Resistant Staphylococcus Aureus (MRSA) Carrier Patients
Status: WITHDRAWN
Conditions: MRSA Colonization
Interventions: DIETARY_SUPPLEMENT: Bio-K+ CL1285|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Surgical and Non Surgical Treatment Option in Poly Cystic Ovary Cases
Status: RECRUITING
Conditions: Poly Cystic Ovary Treatment for Infertility
Interventions: OTHER: Non Surgical treatment|PROCEDURE: laparoscopic drilling|BEHAVIORAL: Treatment of Poly cystic ovary for infertility by Life style modification|PROCEDURE: Treatment of Poly cystic ovary for infertility by Assisted reproductive technique
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Adagrasib in Combination With BI 1701963 in Patients With Cancer (KRYSTAL 14)
Status: COMPLETED
Conditions: Advanced Cancer|Metastatic Cancer|Malignant Neoplasm of Colon|Malignant Neoplasm of Lung|Malignant Neoplastic Disease
Interventions: DRUG: MRTX849|DRUG: BI 1701963
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Smart Reminders to Promote Home-based Cognitive Training
Status: RECRUITING
Conditions: Adherence, Treatment
Interventions: BEHAVIORAL: Adherence Promotion With Person-centered Technology (APPT) System|BEHAVIORAL: Standard Reminder System (Active Control)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Trial to Determine the Safety and Anti-tumor Activity Profile of the Combination of Cetuximab and Concomitant Cisplatin Plus 5-Fluorouracil (5-FU) in Subjects With Recurrent and/or Metastatic Squamous Cell Carcinoma in Head and Neck
Status: COMPLETED
Conditions: Squamous Cell Carcinoma of the Head and Neck
Interventions: BIOLOGICAL: Cetuximab|DRUG: Cisplatin|DRUG: 5-Fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Controlled Evaluation of Robotic Cardiac Surgery Training Modalities
Status: COMPLETED
Conditions: Robotic Surgery Simulation Training
Interventions: OTHER: Wet Lab|OTHER: Dry Lab|OTHER: Virtual Reality
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: The Safety and Efficacy of Human Umbilical Cord Mesenchymal Stem Cells (19#iSCLife®-ACI) in the Treatment of Acute Cerebral Infarction
Status: SUSPENDED
Conditions: Cerebral Infarction
Interventions: BIOLOGICAL: Allogeneic umbilical cord mesenchymal stem cells (SCLnow 19#)|DRUG: Aspirin Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Combining Biomarkers (AFP, AFP-L3, and PIVKA-II) and Image Tools for Early Detection of Hepatocellular Carcinoma
Status: RECRUITING
Conditions: Liver Cirrhosis|Hepatocellular Carcinoma|Surveillance
Interventions: DIAGNOSTIC_TEST: AFP-L3|DIAGNOSTIC_TEST: AFP|DIAGNOSTIC_TEST: PIVKA-II|DIAGNOSTIC_TEST: Sonography|DIAGNOSTIC_TEST: CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Multidrug Resistance Genes in Patients With Acute Myeloid Leukemia
Status: ACTIVE_NOT_RECRUITING
Conditions: Leukemia
Interventions: GENETIC: gene expression analysis|GENETIC: molecular genetic technique|GENETIC: polymorphism analysis|GENETIC: protein expression analysis|OTHER: diagnostic laboratory biomarker analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Mobilization With Movement on Pain, Function, and Quality of Life in Patients With Thoracic Outlet Syndrome
Status: RECRUITING
Conditions: Thoracic Outlet Syndrome
Interventions: OTHER: Mobilization with Movement (MWM) and Tailored Therapeutic Exercise Program|OTHER: Conventional Physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Gravity on Cardiac Hemodynamics
Status: RECRUITING
Conditions: Diabetes type1|Healthy
Interventions: OTHER: Cardiovascular and Baroreflex stimulation by Tilting|OTHER: Cardiovascular and Baroreflex stimulation by Lower Body Negative Pressure
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: e-VITA: European-Japanese Virtual Coach for Smart Ageing (WAVE II)
Status: ACTIVE_NOT_RECRUITING
Conditions: Older Adults|Quality of Life
Interventions: DEVICE: Virtual coach with NAO robot|DEVICE: Virtual coach with Google Nest Hub (2e generation) group|DEVICE: Virtual coach with Gatebox device|DEVICE: virtual coach with CelesTE robot|OTHER: booklet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Impact of Virtual Reality on the Mental Health of Patients Undergoing Adjuvant Treatment for Colorectal Cancer
Status: RECRUITING
Conditions: Cancer of Colon|Virtual Reality
Interventions: BEHAVIORAL: Standard distraction during chemotherapy treatment period|BEHAVIORAL: Virtual distraction during chemotherapy treatment period
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Posterior Capsule Opacification and Frequency of Nd:YAG Treatment and of Two IOLs: Hoya iMics Y-60H vs. Bausch&Lomb MI60 (MIMI)
Status: COMPLETED
Conditions: Posterior Capsule Opacification|Cataract
Interventions: DEVICE: HOYA iMics Y-60H|OTHER: B&L MI60
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: The Effect of High Dose Folic Acid Versus Placebo on the Rate of Gestational Diabetes or Gestational Hypertension in Pregnant Women
Status: WITHDRAWN
Conditions: Gestational Diabetes|Gestational Hypertension
Interventions: OTHER: Placebo|DIETARY_SUPPLEMENT: Folic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: A Study Of Glasdegib In Healthy Volunteers To Establish The Bioequivalence Of The Phase 2 Formulation To The ICH Formulation
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Glasdegib|OTHER: High Fat, High Calorie Meal|DRUG: Rabeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Potential Biomarkers of the Severity of Endothelial Damage in End-stage Chronic Kidney Failure
Status: TERMINATED
Conditions: End-stage Chronic Kidney Failure
Interventions: BIOLOGICAL: Blood sample|OTHER: Retinal photography:|OTHER: dialyse
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Absolute Bioavailability of BMS-626529 After Oral and Intravenous Dosing
Status: COMPLETED
Conditions: Infection, Human Immunodeficiency Virus
Interventions: DRUG: BMS-663068|DRUG: BMS-626529
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Bioequivalence Study Between Fluticasone Propionate 500 mcg and Salmeterol Xinafoate 50 mcg Inhalation Powder/Respirent Pharmaceuticals vs. ADVAIR DISKUS® 500/50 Inhalation Powder/GSK in Healthy Volunteers
Status: COMPLETED
Conditions: Bioequivalence
Interventions: DRUG: Fluticasone propionate 500 mcg and salmeterol xinafoate 50 mcg/Respirent|DRUG: ADVAIR DISKUS® 500/50
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: CLOTBUST Hands-Free: A Phase I/II Pilot Safety Trial
Status: COMPLETED
Conditions: Stroke
Interventions: DEVICE: 2-MHz transcranial Doppler ultrasound|DEVICE: 2-MHz transcranial Doppler ultrasound insonation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: fMRI Study of Emotion Regulation in Patients Suffering From Obesity With or Without Binge Eating Disorder and Seeking Bariatric Surgery
Status: RECRUITING
Conditions: Obesity|Binge-Eating Disorder
Interventions: BEHAVIORAL: Neurofunctional characterization of emotional regulation (fMRI)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Clinical Trial of Patients With Solid Tumours Receiving Granulocyte Colony Stimulating Factor as Primary Prophylaxis for Chemotherapy-induced Neutropenia, in a Docetaxel Based Regimen
Status: COMPLETED
Conditions: Neoplasms (no Otherwise Specified)
Interventions: DRUG: LENOGRASTIM (GRANOGYTE 34)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Optical Coherence Tomography in Dentistry
Status: RECRUITING
Conditions: Dental Caries|Tooth Demineralization
Interventions: DEVICE: Transbond XT|DEVICE: Protecto®CaF2Nano|DEVICE: Pro Seal®|DEVICE: Opal®Seal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SCREENING
Clinical trial: The Dallas Asthma Brain and Cognition (ABC) Study
Status: RECRUITING
Conditions: Asthma
Interventions: OTHER: Functional and Structural Magnetic Resonance Imaging (research grade)|OTHER: Cognitive Function Testing (non-diagnostic)|OTHER: Asthma and Psychological Questionnaires (non-diagnostic)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Colposcopy and Dynamic Spectral Imaging (DSI)
Status: UNKNOWN
Conditions: Cervical Dysplasia|Cervical Disease|Cervical Lesion|Cervix Cancer|Cervical Cancer|Cervical Neoplasm
Interventions: DIAGNOSTIC_TEST: Dynamic Spectral Imaging (DYSIS)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Immersive Virtual Reality Satisfies the Women in Labor by Distracting Them From Their Labor Pain in Labor on Latent and Active Phase
Status: COMPLETED
Conditions: Labor Pain
Interventions: DEVICE: Oculus Quest All-in-one VR Gaming Headset (128 GB) VR system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Clinical Trial to Assess the Effects of Food on the Bioavailability of CKD-337
Status: COMPLETED
Conditions: Dyslipidemias
Interventions: DIETARY_SUPPLEMENT: High fat diet|DRUG: CKD-337
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Risk of Urinary Retention With Retigabine
Status: TERMINATED
Conditions: Epilepsy
Interventions: DRUG: Non-EZG containing AED polytherapy|DRUG: EZG containing AED polytherapy|DRUG: Non-EZG AED monotherapy|DRUG: EZG AED monotherapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Small Bowel Mucosal Healing Induced by Adalimumab in Crohn's Disease Patients as Assessed by Capsule Endoscopy
Status: UNKNOWN
Conditions: Crohn's Disease
Interventions: DRUG: Treatment with Adalimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of the Insulin Pump in Cystic Fibrosis Patients With Impaired Glucose Tolerance or CFRD and in Type 1 Diabetes Patients.
Status: WITHDRAWN
Conditions: Cystic Fibrosis Related Diabetes
Interventions: DEVICE: Insulin Pump|DRUG: Insulin|PROCEDURE: Oral Glucose Tolerance Test|PROCEDURE: Whole body Protein Turnover
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Pharmacokinetics of GH002 in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: 5 Methoxy N,N Dimethyltryptamine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Single Antiplatelet Treatment With Ticagrelor or Aspirin After Transcatheter Aortic Valve Implantation
Status: RECRUITING
Conditions: Severe Aortic Valve Stenosis|Aortic Valve Stenosis|Transcatheter Aortic Valve Replacement (TAVR)|Transcatheter Aortic Valve Implantation (TAVI)
Interventions: DRUG: Ticagrelor 60mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PrEP Restart for Adolescent Girls and Young Women Using STI Self Testing and Assessment of Risk
Status: RECRUITING
Conditions: HIV Prevention
Interventions: DEVICE: STI test kits (NG, CT and TV) for home use|BEHAVIORAL: Self Administered Behavioural Risk Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Clinical Evaluation of an Investigational Lubricant Eye Gel (FID 115958D)
Status: COMPLETED
Conditions: Dry Eye
Interventions: OTHER: Lubricant Eye Drop|OTHER: Refresh Liquigel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: AZD2171 in Treating Patients With Recurrent Glioblastoma Multiforme
Status: COMPLETED
Conditions: Adult Giant Cell Glioblastoma|Adult Glioblastoma|Adult Gliosarcoma|Recurrent Adult Brain Tumor
Interventions: DRUG: cediranib maleate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Intensive Care Unit Nurse Participation in Post - ICU Follow Up Clinic
Status: ENROLLING_BY_INVITATION
Conditions: Nurse-Patient Relations|Nurse Role
Interventions: BEHAVIORAL: Nurse Encounter Group|OTHER: Nurse control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: ICU Stay in Patients With Low Ejection Fraction Undergoing Cardiac Revascularization: Comparison of On-pump vs Off-pump Coronary Artery Bypass Grafting
Status: COMPLETED
Conditions: Cardiac Revascularization
Interventions: PROCEDURE: Coronary Artery Bypass Grafting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Patient Satisfaction and Microbial Changes in Complete Dentures.
Status: UNKNOWN
Conditions: Satisfaction|Microbial Colonization
Interventions: DEVICE: Thermoplastic complete denture|DEVICE: Conventional acrylic resin complete denture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: IOP Lowering Effect of PLT Versus SLT in Naiv OAG Patients
Status: UNKNOWN
Conditions: Open Angle Glaucoma,|Ocular Hypertension
Interventions: DEVICE: Laser trabeculoplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Study of Efficacy and Safety of AK120, in Subjects With Moderate-to-Severe Atopic Dermatitis
Status: UNKNOWN
Conditions: Atopic Dermatitis
Interventions: DRUG: Placebo|DRUG: AK120|DRUG: AK120
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dose Escalation and Dose Expansion Study of GSK525762 in Combination With Androgen Deprivation Therapy in Participants With Castrate-resistant Prostate Cancer
Status: TERMINATED
Conditions: Solid Tumours
Interventions: DRUG: GSK525762|DRUG: Abiraterone|DRUG: Enzalutamide|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Methoxyflurane Analgesia for Paediatric Injuries
Status: UNKNOWN
Conditions: Pain, Acute
Interventions: DRUG: Methoxyflurane|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Preoperative Intraarterial Chemoembolization Combined With Radiotherpy in Locally Advanced Rectal Cancer
Status: UNKNOWN
Conditions: Rectal Cancer
Interventions: DEVICE: intraarterial chemoembolization|DEVICE: intravenous chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Metastatic Pathologic Fractures, Short Term Results
Status: RECRUITING
Conditions: Pathologic Fracture|Bone Metastases|Metastatic Cancer
Interventions: PROCEDURE: endoprosthetic reconstruction|PROCEDURE: Intramedullary nailing|PROCEDURE: Open reduction internal fixation with plate and screws
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase 1 Dose Escalation Study to Examine the Safety of the P2-VP8 Rotavirus Vaccine
Status: COMPLETED
Conditions: Rotavirus Infection
Interventions: BIOLOGICAL: P2-VP8 subunit rotavirus vaccine|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A First-in-human Study Evaluating AMG 167 in Healthy Men and Postmenopausal Women
Status: COMPLETED
Conditions: Osteopenia
Interventions: DRUG: AMG 167|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bioavailability Study of 3 Tablet Formulations vs. Capsule Formulation of JNJ-56021927 in Fasting Healthy Male Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: JNJ-56021927 Softgel Capsule|DRUG: JNJ-56021927 Tablet Formulation 1|DRUG: JNJ-56021927 Tablet Formulation 2|DRUG: JNJ-56021927 Tablet Formulation 3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Clinical Efficacy of Naproxen, Associated or Not With Esomeprazol, in Lower Third Molar Removal
Status: COMPLETED
Conditions: Pain|Other Surgical Procedures|Impacted Third Molar Tooth
Interventions: DRUG: Surgery with Naproxen|DRUG: Surgery with Naproxen and Esomeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Understanding the Metabolic and Functional Derangement of Primary Mitral Regurgitation: a Feasibility Study Using Carbon 11(C-11) Acetate Cardiac Positron Emission Tomography Magnetic Resonance Imaging (PET-MRI)
Status: NOT_YET_RECRUITING
Conditions: Mitral Valve Regurgitation
Interventions: DRUG: [11C] acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Intraperitoneal Magnesium Sulphate and Bupivacaine Versus Intravenous Analgesia in Laparoscopic Surgeries in Pediatrics
Status: COMPLETED
Conditions: Intraperitoneal Magnesium Sulphate in Laparoscope in Pediatrics
Interventions: DRUG: Magnesium Sulfate & bupivacaine|DRUG: paracetamol & ketorolac
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Calcipotriol Plus Betamethasone Dipropionate Ointment in Patients With Psoriasis Vulgaris
Status: COMPLETED
Conditions: Psoriasis Vulgaris
Interventions: DRUG: Calcipotriol plus betamethasone dipropionate ointment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: S0521, Combination Chemotherapy With or Without Gemtuzumab Followed By Tretinoin, Mercaptopurine, and Methotrexate or Observation in Treating Patients With Acute Promyelocytic Leukemia
Status: COMPLETED
Conditions: Leukemia
Interventions: DRUG: mercaptopurine|DRUG: methotrexate|DRUG: tretinoin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Autoantibody Reduction for Acute Exacerbations of Idiopathic Pulmonary Fibrosis
Status: COMPLETED
Conditions: Idiopathic Pulmonary Fibrosis, Acute Fatal Form
Interventions: DRUG: Autoantibody Reductive Therapy|DRUG: Treatment as Usual (TAU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fibrine Clot-augmented Repair of Longitudinal Meniscus Tears
Status: RECRUITING
Conditions: Meniscus Tear|Meniscus Lesion|Fibrin Blood Clot|Knee Injuries
Interventions: PROCEDURE: Fibrine Clot-augmented Meniscal Repair|PROCEDURE: Conventional Meniscal Repair
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Melatonin in Sleep Problems of Hemodialysis and Peritoneal Dialysis Patients
Status: COMPLETED
Conditions: Hemodialysis|Peritoneal Dialysis|Sleep Problems
Interventions: DRUG: Melatonin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Post-operative Biochemical Recurrence in Patients Submitted to Radical Prostatectomy Under General Opioid-free Anesthesia Compared to Conventional General Anesthesia
Status: UNKNOWN
Conditions: Prostate Cancer
Interventions: DRUG: opioid-free group|DRUG: Opioid Group|PROCEDURE: transversus abdominal plane block with ropivacaine|PROCEDURE: transversus abdominal plane block with placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: An Effectiveness and Safety Study of CNTO 1275 in Patients With Active Psoriatic Arthritis
Status: COMPLETED
Conditions: Psoriatic Arthritis
Interventions: DRUG: CNTO 1275 63 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vestipitant Or Vestipitant/Paroxetine Combination In Subjects With Tinnitus And Hearing Loss.
Status: COMPLETED
Conditions: Tinnitus
Interventions: DRUG: Vestipitant|DRUG: Vestipitant + Paroxetine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Temozolomide for Treatment of Brain Metastases From Non-Small Cell Lung Cancer (Study P03247)
Status: COMPLETED
Conditions: Carcinoma, Non-Small-Cell Lung|Neoplasm Metastasis|Brain Neoplasms
Interventions: DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ketamine for Severe Adolescent Depression: Intermediate-term Safety and Efficacy
Status: TERMINATED
Conditions: Major Depressive Disorder
Interventions: DRUG: Ketamine infusion|DRUG: Midazolam infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of miRNA 371 in Patients With Germ Cell Tumors
Status: RECRUITING
Conditions: Germ Cell Tumor|Metachronous Malignant Neoplasm|Seminoma|Stage I Testicular Cancer AJCC v8|Stage IA Testicular Cancer AJCC v8|Stage IB Testicular Cancer AJCC v8|Stage IS Testicular Cancer AJCC v8
Interventions: OTHER: Biomarker Analysis|PROCEDURE: Blood Product Collection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Difluprednate Ophthalmic Emulsion in the Treatment of Severe Uveitis
Status: COMPLETED
Conditions: Uveitis|Panuveitis
Interventions: DRUG: Difluprednate Ophthalmic Emulsion
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Influence of Aircraft Noise Exposure on Renal Hemodynamic in Healthy Individuals
Status: COMPLETED
Conditions: Healthy Individuals|Arterial Hypertension
Interventions: PROCEDURE: Noise|PROCEDURE: Silence
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: DIAGNOSTIC
Clinical trial: E7080 in Combination With Carboplatin + Gemcitabine Versus Carboplatin + Gemcitabine Alone as Second Line Therapy in Patients With Platinum-Sensitive Recurrent Ovarian Cancer by CA125
Status: TERMINATED
Conditions: Ovarian Cancer
Interventions: DRUG: Lenvatinib|DRUG: Carboplatin|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Weekly Dosing of Malarone ® for Prevention of Malaria
Status: COMPLETED
Conditions: Malaria
Interventions: DRUG: Atovaquone Proguanil|OTHER: Procedure - malaria challenge
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of the Number of Needle Revolutions Inside the Node on the Diagnostic Yield of EBUS-TBNA in Sarcoidosis
Status: COMPLETED
Conditions: Sarcoidosis
Interventions: PROCEDURE: 10 revolutions|PROCEDURE: 20 revolutions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Predictive Value of Progastrin Titer at Diagnosis and of Progastrin Kinetics During Treatment in Cancer Patients
Status: RECRUITING
Conditions: Cancer|Breast Cancer|Gastric Cancer|Renal Cancer|Prostate Cancer|Melanoma|Lung Cancer|Hepatocellular Cancer|Colorectal Cancer|Head and Neck Cancer|Pancreatic Cancer|Ovarian Cancer|Glioblastoma|Endometrial Cancer|Bladder Cancer|Esophageal Cancer|B-cell Lymphoma
Interventions: OTHER: Blood draws
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Preoperative Oral Carbohydrate Loading on Elderly Patient Quality of Recovery in Total Knee Arthroplasty
Status: COMPLETED
Conditions: Quality Of Recovery
Interventions: DIETARY_SUPPLEMENT: Carbohydrate group (Group OC)|DIETARY_SUPPLEMENT: Placebo group (Group OP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of a Retroviral Replicating Vector Given Intravenously to Patients Undergoing Surgery for Recurrent Brain Tumor
Status: COMPLETED
Conditions: Glioblastoma Multiforme|Anaplastic Astrocytoma|Anaplastic Oligodendroglioma|Anaplastic Oligoastrocytoma
Interventions: BIOLOGICAL: Toca 511|DRUG: Toca FC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adjunctive Study of AL-37807 Ophthalmic Suspension
Status: COMPLETED
Conditions: Open-Angle Glaucoma|Ocular Hypertension
Interventions: DRUG: AL-37807 ophthalmic suspension, 0.1%|DRUG: Timolol gel forming solution, 0.5%|OTHER: AL-37807 ophthalmic solution vehicle|DRUG: Latanoprost ophthalmic solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study to Evaluate the Efficacy and Safety of Cilostazol and Probucol in Combination on Patients With Diabetic Nephropathy
Status: COMPLETED
Conditions: Diabetic Nephropathy
Interventions: DRUG: Probucol|DRUG: Probucol and Cilostazol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Single Center Clinical Evaluation of Same Sitting Hybrid Revascularization: Robotic Coronary Artery Bypass Grafting and Percutaneous Coronary Intervention for the Treatment of Coronary Artery Disease
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: PROCEDURE: Hybrid CABG/PCI|PROCEDURE: Off Pump CABG
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Hard and Soft Tissue Change During Maxillary Expansion Using a Computer-aided Design / Computer-aided Manufacturing Appliance.
Status: NOT_YET_RECRUITING
Conditions: Palatal Expansion Technique
Interventions: PROCEDURE: Maxillary Expansion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Exenatide Once Weekly and Once-Daily Insulin Glargine in Patients With Type 2 Diabetes Treated With Metformin Alone or in Combination With Sulfonylurea (DURATION - 3)
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Exenatide Once Weekly|DRUG: Insulin Glargine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Home-based Exercise for Frail Individuals Prior to Cardiac Surgery
Status: RECRUITING
Conditions: Frailty|Pre-operative Exercise|Prehabilitation|Cardiac Surgery|Telerehabilitation
Interventions: BEHAVIORAL: Prehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Use of Lung US, Fluoroscopy and Auscultation to Confirm Proper Positioning of Left Sided DLT : A Comparative Study
Status: NOT_YET_RECRUITING
Conditions: Endotracheal Tube Wrongly Placed During Anesthetic Procedure
Interventions: DEVICE: Double lumen endotracheal tube
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: International Lung Screen Trial (ILST)
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-small Cell Lung Cancer|Lung Neoplasms|Respiratory Tract Neoplasms|Thoracic Neoplasms|Neoplasms by Site|Neoplasms|Lung Diseases|Respiratory Tract Diseases|Smokers at Risk of Lung Cancer
Interventions: DIAGNOSTIC_TEST: Low dose CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: The Effect of Cycloserine on Smoking Behavior in Nicotine Dependent Smokers
Status: COMPLETED
Conditions: Smoking
Interventions: DRUG: Cycloserine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability Study of Larazotide Acetate in Celiac Disease Subjects
Status: COMPLETED
Conditions: Celiac Disease
Interventions: DRUG: larazotide acetate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Technology-Enhanced Palliative Care for Advanced Cancer Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Malignant Solid Neoplasm
Interventions: OTHER: Interview|OTHER: Palliative Therapy|OTHER: Palliative Therapy|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Efficacy of Valsartan vs Atenolol and Hydrochlorothiazide Combination on Blood Flow in Hypertensive Patients
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Atenolol|DRUG: Hydrochlorothiazide (HCTZ))|DRUG: Valsartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Advanced Hybrid Closed Loop System (AHCL) in Older Patients With Type 1 Diabetes Mellitus
Status: RECRUITING
Conditions: Diabetes Mellitus, Type 1
Interventions: DEVICE: MiniMed™ 780G Advanced Hybrid Closed Loop (AHCL) system|OTHER: MDI/CSII
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Open-label Study to Evaluate Long-term Safety and Efficacy of SPN-812 (Viloxazine Extended-release Capsule)
Status: ACTIVE_NOT_RECRUITING
Conditions: Attention-Deficit/Hyperactivity Disorder
Interventions: DRUG: SPN-812
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability of Pioglitazone-Azilsartan in Subjects With Type 2 Diabetes
Status: TERMINATED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Pioglitazone-Azilsartan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Gastric Varices Using EUS Guided Techniques
Status: COMPLETED
Conditions: Gastric Varix
Interventions: PROCEDURE: EUS-guided injection of coils with cyanoacrylate|PROCEDURE: EUS-guided injection of coils
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Comparing Arndt and Tappa Endobronchial Blocker During Pediatric One Lung Ventilation
Status: UNKNOWN
Conditions: Lung Diseases
Interventions: DEVICE: Tappa Endobronchial Blocker|DEVICE: Arndt Endobronchial Blocker
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Malnutrition in Chronic Pancreatitis, Trans-sectoral Study
Status: UNKNOWN
Conditions: Chronic Pancreatitis|Malnutrition|Sarcopenia
Interventions: OTHER: Intensified Nutritional Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Open, Randomised, Parallel Group Multicentre Study to Compare the Efficacy and Safety of Flutiform® pMDI vs Fluticasone pMDI Plus Formoterol DPI in Adolescent and Adult Subjects With Mild to Moderate-severe Persistent, Reversible Asthma
Status: COMPLETED
Conditions: Asthma Bronchiale
Interventions: DRUG: Flutiform|DRUG: Flixotide plus Foradil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HIIH Versus HMC: Randomized Clinical Trial
Status: RECRUITING
Conditions: Healthy People
Interventions: OTHER: High-intensity interval Hydrogynmastics|OTHER: Hydrogynmastics Continuous Moderate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Brain Activity Associated With Inhibition of Action in Attention-deficit
Status: RECRUITING
Conditions: Attention Deficit|Hyperactivity Disorder
Interventions: OTHER: EEG experimental sessions 1|OTHER: EEG experimental sessions 2
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Atezolizumab in Combination With Bevacizumab, Carboplatin and Pemetrexed for EGFR-mutant Metastatic NSCLC Patients After Failure of EGFR Tyrosine Kinase Inhibitors
Status: UNKNOWN
Conditions: NSCLC Stage IIIB|NSCLC Stage IV|EGFR Activating Mutation
Interventions: DRUG: Atezolizumab|DRUG: Bevacizumab|DRUG: Carboplatin|DRUG: Pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Asymptomatic Bacteriuria, Hyponatremia and Geri-atric Syndrome
Status: RECRUITING
Conditions: Asymptomatic Bacteriuria|Frailty|Geriatric Syndrome|SIADH
Interventions: DIAGNOSTIC_TEST: urine sample|DIAGNOSTIC_TEST: Blood and urine sample
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: EPI-743 for Metabolism or Mitochondrial Disorders
Status: COMPLETED
Conditions: Mitochondrial Disease|Neurology|Myopathy
Interventions: DRUG: EPI-743|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Application of Iced Normal Saline Combined With Cocktail Perfusion in Total Knee Arthroplasty
Status: COMPLETED
Conditions: Pain, Postoperative|Blood Loss, Postoperative
Interventions: DRUG: iced normal saline|DRUG: Tranexamic acid injection|OTHER: Cocktail (composing by Ropivacaine, Morphine and Epinephrine) perfusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Estimation Study to Assess the Effect of Severe Renal Impairment and End-stage Renal Disease Hemodialysis on the Pharmacokinetics of Evolocumab
Status: COMPLETED
Conditions: Hyperlipidemia|Mixed Dyslipidemia
Interventions: BIOLOGICAL: Evolocumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Electrical Impedance Tomography for Identification of Optimal Positive End-expiratory Pressure in Newborn Infants
Status: RECRUITING
Conditions: Positive End-expiratory Pressure (PEEP)
Interventions: DIAGNOSTIC_TEST: Electrical impedance tomography (EIT)|DIAGNOSTIC_TEST: Forced oscillation technique (FOT)|DIAGNOSTIC_TEST: Saturation oxygenation pressure index (SOPI)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Apatinib in the Treatment of Patients With EGFR T790M-Negative NSCLC
Status: UNKNOWN
Conditions: Lung Diseases|Neoplasms|Respiratory Tract Diseases|Thoracic Neoplasms|Non-Small-Cell Lung
Interventions: DRUG: Apatinib|DRUG: EGFR-TKI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, and Immunogenicity Study of a 24-Valent Pneumococcal Conjugate Vaccine (VAX-24) in Adults
Status: COMPLETED
Conditions: Pneumococcal Vaccines
Interventions: BIOLOGICAL: 24 valent pneumococcal conjugate vaccine|BIOLOGICAL: 20 valent pneumococcal conjugate vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparing Five Oral Analgesics for Treatment of Acute Pain in the Emergency Department (ED)
Status: COMPLETED
Conditions: Musculoskeletal Pain
Interventions: DRUG: oxycodone/APAP|DRUG: hydrocodone/APAP|DRUG: codeine/APAP|DRUG: 400 ibuprofen/APAP|DRUG: 800 ibuprofen/APAP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ketorolac on Postoperative Pain Reduction in Pediatric Patients With Adenotonsillectomy
Status: ACTIVE_NOT_RECRUITING
Conditions: Adenotonsillar Hypertrophy|Obstructive Sleep Apnea|Sleep-Disordered Breathing|Acute Post Operative Pain
Interventions: DRUG: Ketorolac
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Allogeneic Stem Cell Transplantation (ALLOSCT) in Recessive Dystrophic Epidermolysis Bullosa (RDEB)
Status: TERMINATED
Conditions: Epidermolysis Bullosa
Interventions: DRUG: Palifermin|DRUG: Fludarabine|DRUG: Busulfan|DRUG: Lorazepam|DRUG: Alemtuzumab|DRUG: Tacrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Everolimus, Bicalutamide, and Leuprolide Acetate in Treating Patients Undergoing Radiation Therapy For High-Risk Locally Advanced Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: bicalutamide|DRUG: everolimus|DRUG: leuprolide acetate|RADIATION: external beam radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 3/4 Study of a Recombinant Protein-Free Factor VIII (rAHF-PFM): Comparison of Continuous Infusion Versus Intermittent Bolus Infusion in Hemophilia A Subjects Undergoing Major Orthopedic Surgery
Status: COMPLETED
Conditions: Hemophilia A
Interventions: DRUG: Recombinant Protein-Free Factor VIII (rAHF-PFM)|DRUG: Recombinant Protein-Free Factor VIII (rAHF-PFM)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neutrophil-lymphocyte and Platelet-lymphocyte Ratios and Their Relations to Vascular Comlications and Glycemic Control in Patients With Type 2 Diabetes Attending The Diabetes Center of Assiut University Hospitals
Status: NOT_YET_RECRUITING
Conditions: Vascular Complication, Diabetic
Interventions: RADIATION: Echocardiogram
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: ER Niacin/Laropiprant Impact on Cardiovascular Markers and Atheroprogression in HIV-infected Individuals on cART
Status: TERMINATED
Conditions: HIV|Atherosclerosis
Interventions: DRUG: niacin/laropiprant|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of Rapamycin as Treatment for Autosomal Dominant Polycystic Kidney Disease (ADPKD)
Status: COMPLETED
Conditions: Polycystic Kidney Diseases
Interventions: DRUG: Rapamune
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of High-intensity Interval Training on Myocardial Strain in Metabolic Syndrome Patients
Status: COMPLETED
Conditions: High-Intensity Interval Training|Metabolic Syndrome|Myocardial Dysfunction
Interventions: BEHAVIORAL: High-intensity interval training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT