pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: The Role of a Motion Sensor With Accompanying Web Application on Step Counts, Energy Balance, and Metabolic Markers in Nurses
Status: COMPLETED
Conditions: Cardiovascular Risk Factor|Cardiovascular Diseases
Interventions: BEHAVIORAL: Motion sensor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Different Doses of Salacinol Extract on Glycemic and Insulinemic Response in Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: DRUG: nutritional herbal extract from Salacia oblonga
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Nutritional Counseling for Cancer Patients
Status: COMPLETED
Conditions: Esophageal Cancer|Gastric Cancer|Uterine Cancer
Interventions: BEHAVIORAL: Weekly nutritional counseling|DIETARY_SUPPLEMENT: Forticare®.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Visual Acuity After the Combined Binocular Implantation of +2.5 Diopters and +3.0 Diopters ReSTOR Multifocal Intraocular Lenses.
Status: COMPLETED
Conditions: Cataract
Interventions: DEVICE: Binocular cataract surgery with phacoemulsification and implantation of multifocal intraocular lenses
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Laparoscopic Ventrosuspension for Women With Retroverted Uterus and Pelvic Pain Syndromes: A New Approach
Status: UNKNOWN
Conditions: Chronic Pelvic Pain
Interventions: PROCEDURE: Laparoscopic guided Ventrosuspension
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Framework For Linking Sequential Pattern Rules in DLD: Perception in Adults
Status: RECRUITING
Conditions: Developmental Language Disorder|Speech Sound Disorder|Specific Language Impairment
Interventions: BEHAVIORAL: Sensitivity to phonological rules: Adults|BEHAVIORAL: Sensitivity to semantic category cues: Adults
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Peer to Peer Mentoring For Individuals With Early Inflammatory Arthritis: An Effectiveness Study (Pilot RCT)- Peer Mentor Training
Status: COMPLETED
Conditions: Early Inflammatory Arthritis
Interventions: BEHAVIORAL: Peer Mentor Training
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: |Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Influence of Sevoflurane and Desflurane on Postoperative Sore Throat
Status: UNKNOWN
Conditions: Hip Arthroplasty
Interventions: DRUG: Sevoflurane|DRUG: Desflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Cell Therapy by Bone Marrow-derived Mononuclear Cells (BMC) for Large Bone Defect Repair: Phase-I Clinical Trial
Status: COMPLETED
Conditions: Humerus Fracture Displaced Proximal
Interventions: OTHER: BMC2012
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dexamethasone in the Treatment of Bronchiolitis in Patients With Either Eczema and or Family History of Asthma
Status: COMPLETED
Conditions: Bronchiolitis
Interventions: DRUG: Dexamethasone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cytotoxic T Cells and Interleukin-2 in Treating Adult Patients With Recurrent Brain Tumors
Status: COMPLETED
Conditions: Brain and Central Nervous System Tumors
Interventions: BIOLOGICAL: aldesleukin|BIOLOGICAL: muromonab-CD3|BIOLOGICAL: therapeutic tumor infiltrating lymphocytes|PROCEDURE: conventional surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Reverse Drilling Technique in Improving Outcomes After Arthroscopic Anterior Cruciate Ligament Reconstruction
Status: NOT_YET_RECRUITING
Conditions: Anterior Cruciate Ligament Injuries
Interventions: PROCEDURE: Reverse drilling technique|PROCEDURE: Traditional extraction drilling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of Hematopoietic Stem Cell Transplantation From Two Matched Sibling Donors in Treating Patients With Poor Prognosis Acute Leukemia and Advanced Lymphoproliferative Malignancies
Status: UNKNOWN
Conditions: Relapsed and Refractory Acute Leukemia
Interventions: BIOLOGICAL: Double matched sibling transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antisecretory Factor In Severe Traumatic Brain Injury
Status: RECRUITING
Conditions: Traumatic Brain Injury
Interventions: DIETARY_SUPPLEMENT: Salovum|DIETARY_SUPPLEMENT: Placebo egg yolk powder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Heavier- and Lighter-load Resistance Training on Arm and Leg Muscle Mass in Young Adult Women
Status: COMPLETED
Conditions: Skeletal Muscle Hypertrophy
Interventions: OTHER: Higher-load resistance training|OTHER: Lower-load resistance training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Lymphocyte Reconstitution After Administration of Pegfilgrastim Versus Filgrastim After Peripheral Stem Cell Transplantation
Status: TERMINATED
Conditions: Non Hodgkin Lymphoma
Interventions: DRUG: Pegfilgrastim|DRUG: Filgrastim
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pre-Operative Trial (PGHA vs. PGH) for Resectable Pancreatic Cancer
Status: TERMINATED
Conditions: Pancreatic Cancer Resectable
Interventions: DRUG: Gemcitabine, Nab-Paclitaxel, hydroxychloroquine and Avelumab|DRUG: Gemcitabine, Nab-Paclitaxel, and hydroxychloroquine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: New Medication Treatment for Stimulant Dependence
Status: COMPLETED
Conditions: Cocaine Dependence
Interventions: DRUG: Ondansetron|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Olfactory Training in Chronic Rhinosinusitis
Status: WITHDRAWN
Conditions: Olfactory Dysfunction
Interventions: OTHER: Olfactory Training with Essential Oils|OTHER: Olfactory Training with Pure Fragrance Oils
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Perioperative Chemoimmunotherapy With/Without Preoperative Chemoradiation for Locally Advanced Gastric Cancer
Status: RECRUITING
Conditions: Stomach Neoplasms|Esophagogastric Junction Disorder|Neoadjuvant Therapy|Chemoradiotherapy|Immunotherapy|Gastrectomy|Adenocarcinoma|Adjuvant Therapy
Interventions: DRUG: Oxaliplatin|DRUG: Tegafur-Gimeracil-Oteracil|DRUG: Sintilimab|RADIATION: Concurrent chemoradiation|PROCEDURE: D2/R0 gastrectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: IMPACT: A Safety and Feasibility Study of the IOWA Approach Cardiac Ablation System
Status: COMPLETED
Conditions: Paroxysmal Atrial Fibrillation
Interventions: DEVICE: IOWA Approach Cardiac Ablation System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intravitreal Bevacizumab (Avastin) for Pseudophakic Macular Edema (PME)
Status: WITHDRAWN
Conditions: Cystoid Macular Edema
Interventions: DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: The Effect of Dienogest vs. Norethindrone Acetate Treatment in Endometriosis
Status: COMPLETED
Conditions: Endometriosis
Interventions: DRUG: Dienogest Pill|DRUG: Norethindrone Acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Kegel Exercise Device in Strengthening Pelvic Floor and Treating Urinary Incontinence (UI)
Status: COMPLETED
Conditions: Stress Urinary Incontinence|Sexual Dysfunction
Interventions: DEVICE: Pelvic floor exerciser
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improving Post-acute Stroke Follow-up Care by Adopting Telecare Consultations in a Nurse-led Clinic
Status: RECRUITING
Conditions: Stroke
Interventions: PROCEDURE: Telecare consultation|PROCEDURE: Usual face-to-face consultation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Paclitaxel (Albumin-bound) and Oxaliplatin for Advanced Hepatobiliary and Malignant Tumors
Status: UNKNOWN
Conditions: Advanced Hepatobiliary and Malignant Tumors
Interventions: DRUG: albumin-bound paclitaxel + oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Is Second Knee at Risk During Simultaneous Bilateral Total Knee Arthroplasty.
Status: UNKNOWN
Conditions: Osteoarthritis, Knee|Infection|Periprosthetic Fracture Around Prosthetic Joint Implant
Interventions: PROCEDURE: First Arthroplasty|PROCEDURE: Second Arthroplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Tarceva and Targretin in Stage I-II Lung Cancer
Status: COMPLETED
Conditions: Carcinoma, Non-small-cell Lung
Interventions: DRUG: erlotinib (Tarceva) and bexarotene (Targretin)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of RP-6306 With Gemcitabine in Advanced Solid Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Adult Solid Tumor
Interventions: DRUG: RP-6306 (oral PKMYT1 inhibitor)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Clinical Impact of the Basophil Activation Test to Diagnose Food Allergy
Status: RECRUITING
Conditions: Food Allergy|Food Allergy in Infants|Food Allergy in Children|Food Allergen Sensitisation|Milk Allergy|Egg Allergy|Nut Allergy
Interventions: DIAGNOSTIC_TEST: Basophil activation test (BAT)|DIAGNOSTIC_TEST: Oral food challenge (OFC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Impact of Intraduodenal Acetic Acid Infusion on Pancreatic Duct Cannulation During Endoscopic Retrograde Cholangiopancreatography: a Double-blind, Randomized Controlled Trial
Status: COMPLETED
Conditions: Pancreatic Duct Cannulation During Endoscopic Retrograde Choledochopancreatography
Interventions: DIETARY_SUPPLEMENT: acetic acid|DIETARY_SUPPLEMENT: saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Kinesthetic Motor Imagery Training and Dual Task Training on Cognitive and Motor Functions in Healthy Youth
Status: RECRUITING
Conditions: Imagery, Psychotherapy|Exercise|Stroop Test|Healthy Participants|Multi-Tasking Behavior|Balance, Postural|Motor Activity|Cognitive Function|Cognitive Rehabilitation|Cognitive Test
Interventions: OTHER: Dual task training|OTHER: Kinesthetic motor imagery training|OTHER: Balance exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Total Knee Replacement Study Using Standard Cutting Guide vs Otismed MRI Generated Cutting Guide
Status: COMPLETED
Conditions: Osteoarthritis of the Knee
Interventions: DEVICE: Standard cutting guide for TKA|DEVICE: Otismed MRI generated cutting guide for TKA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: On-treatment Biomarkers in Metastatic Colorectal Cancer for Life
Status: RECRUITING
Conditions: Metastatic Colorectal Cancer|Chemotherapy Effect|Peritoneal Metastases|Liver Metastasis Colon Cancer|Lung Metastases
Interventions: DRUG: Chemotherapy|PROCEDURE: Resection of the primary tumor|PROCEDURE: Resection of tumour metastases|PROCEDURE: Blood sampling during chemotherapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Co-Use of Opioid Medications and Alcohol Prevention Study
Status: RECRUITING
Conditions: Alcohol Drinking|Opioid Use
Interventions: BEHAVIORAL: Alcohol-targeted Brief Intervention-Medication Therapy Management|BEHAVIORAL: Standard medication counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Ablation of Intestinal Metaplasia Containing Dysplasia
Status: COMPLETED
Conditions: Barrett Esophagus
Interventions: DEVICE: Ablation System plus anti-secretory medication|DEVICE: Sham procedure plus anti-secretory medication
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Landmark Guided Intercostobrachial Nerve Block Versus Serratus Plane Block After Supraclavicular Plexus Block for Anesthesia in Creation of Arteriovenous Fistula in the Medial Side of the Arm
Status: RECRUITING
Conditions: Intercostobrachial Nerve Block|Serratus Plane Block|Supraclavicular Plexus Block|Arteriovenous Fistula
Interventions: OTHER: Landmark Guided Intercostobrachial Nerve Block|OTHER: Ultrasound Guided Intercostobrachial Nerve Block|OTHER: Serratus Plane Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Microfluidic Chip vs Density Gradient Centrifugation on the Euploidy Rate of Pre-implantation Genetic Testing
Status: NOT_YET_RECRUITING
Conditions: Infertility|Genetic Disease|Chromosomal Rearrangement|Aneuploidy
Interventions: DEVICE: microfluidic chip|DEVICE: density gradient centrifugation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 3-year Clinical Performance of Prefabricated and Composite Veneers
Status: COMPLETED
Conditions: Dental Diseases|Tooth Discoloration
Interventions: PROCEDURE: Edelweiss prefabricated veneers|PROCEDURE: Ceram-X Duo SphereTec with U-Veneer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Feeding Length on the Oxygenation Instability Among Premature Infants
Status: COMPLETED
Conditions: Premature Infant|Respiratory Disease
Interventions: PROCEDURE: Continuous gavage feeding|PROCEDURE: Bolus feeding
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of LY2623091 in Male and Females With Chronic Kidney Disease
Status: COMPLETED
Conditions: Chronic Kidney Disease
Interventions: DRUG: LY2623091|DRUG: Eplerenone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Aquatic and Land Aerobic Training, Cardiorespiratory and Metabolic Variables in Cardiorespiratory Diseases
Status: UNKNOWN
Conditions: Arteriosclerosis, Coronary
Interventions: OTHER: Exercise, Aerobic (Water based)|OTHER: Land Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Oral Ketamine in the Treatment of Depression and Anxiety in Patients With Cancer
Status: TERMINATED
Conditions: Cancer|Depression|Anxiety
Interventions: DRUG: Ketamine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phase III Study Comparing Two Methods of Cardioplegia in Aortic Valve Surgery Custodiol-N Versus Custodiol
Status: COMPLETED
Conditions: Aortic Valve Disease|Coronary Artery Disease (CAD)
Interventions: DRUG: Custodiol-N|DRUG: Custodiol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Diathermy on Healing Power of Cesarean Section Scar
Status: COMPLETED
Conditions: Healing Surgical Wounds
Interventions: DEVICE: diathermy|DEVICE: scalpel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Efficacy Study Comparing the Effect of Clomiphencitrate to an Antagonist Protocol
Status: COMPLETED
Conditions: Female Infertility|Ovarian Insufficiency
Interventions: DRUG: High Dose Clomiphencitrat|DRUG: Low Dose Clomiphencitrat|DRUG: High Dose Placebo|DRUG: Low dose Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial Comparing Gemcitabine With and Without IMM-101 in Advanced Pancreatic Cancer
Status: COMPLETED
Conditions: Advanced Pancreatic Cancer
Interventions: BIOLOGICAL: IMM-101|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lay Health Worker Outreach in Increasing Colorectal Cancer Screening in Asian Americans
Status: COMPLETED
Conditions: Colorectal Carcinoma|Health Status Unknown|Healthy Subject
Interventions: OTHER: Educational Intervention|OTHER: Educational Intervention|OTHER: Informational Intervention|OTHER: Survey Administration|BEHAVIORAL: Telephone-Based Intervention|BEHAVIORAL: Telephone-Based Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Improving Sleep and the Patient Experience in the Emergency Department
Status: COMPLETED
Conditions: Sleep Deprivation
Interventions: DEVICE: Sleep mask|OTHER: Standard of care|DEVICE: Ear Plugs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Exploring Muscle Breakdown During Exercise Recovery
Status: COMPLETED
Conditions: Muscle Damage|Healthy
Interventions: DIETARY_SUPPLEMENT: Recover Vegan Protein Supplement|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Safety, Pharmacokinetics and Efficacy of FMX114 Versus Vehicle in Adults With Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: FMX114|OTHER: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of PEP02, Irinotecan or Docetaxel in Gastric or Gastroesophageal Junction Adenocarcinoma
Status: COMPLETED
Conditions: Stomach Neoplasms|Esophageal Neoplasms
Interventions: DRUG: PEP02|DRUG: irinotecan|DRUG: docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low Intensity Ultrasound Neuromodulation of Repetitive Negative Thinking In Depression
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: OTHER: Low-intensity focused ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Cost-effectiveness of CYP2D6 and CYP2C19 Genotyping in Psychiatric Patients in Curacao
Status: COMPLETED
Conditions: CYP2D6, Psychiatric Patients
Interventions: OTHER: Dose adjustment according to genotype
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mediators and Moderators of Treatment Outcome in Recent-Onset Psychosis
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder|Bipolar Disorder With Psychotic Features|Major Depression With Psychotic Features|Psychotic Disorder Not Otherwise Specified (NOS)
Interventions: BEHAVIORAL: Group Cognitive Behavioral Therapy|BEHAVIORAL: Multifamily Group Psychoeducation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Enhanced Multicenter Dietary Portfolio Study
Status: WITHDRAWN
Conditions: Cardiovascular Diseases|Type 2 Diabetes|Hypercholesterolemia
Interventions: BEHAVIORAL: Enhanced portfolio plus structured exercise|BEHAVIORAL: High fiber diet plus routine exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prebiotics in Patients With Non-alcoholic Liver Disease
Status: COMPLETED
Conditions: Non-alcoholic Fatty Liver Disease|Metabolic Syndrome
Interventions: DIETARY_SUPPLEMENT: ITF (Inulin/OFS 75/25)|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intracardiac Echocardiography Guided Watchman Device Implant
Status: RECRUITING
Conditions: Atrial Fibrillation|Left Atrial Appendage Thrombosis
Interventions: DEVICE: Intracardiac Echocardiography (ICE)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study In Healthy Subjects To Evaluate The Photo-Irritant Potential Of Eltrombopag
Status: COMPLETED
Conditions: Purpura, Thrombocytopaenic, Idiopathic
Interventions: DRUG: Ciprofloxacin|DRUG: Eltrombopag|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dietary Nitrate, Vascular Function and Inflammation
Status: COMPLETED
Conditions: Hypertension|Inflammation
Interventions: DIETARY_SUPPLEMENT: High-nitrate intervention|DIETARY_SUPPLEMENT: Low-nitrate intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 3B Study to Evaluate Bone Mineral Density With Long-Term Use of Relugolix Combination Tablet in Women With Uterine Fibroids or Endometriosis
Status: RECRUITING
Conditions: Uterine Fibroids|Endometriosis
Interventions: DRUG: Relugolix Combination Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Preladenant for the Treatment of Neuroleptic Induced Akathisia (Study P05145)
Status: TERMINATED
Conditions: Akathisia, Drug-Induced|Antipsychotic Agents|Movement Disorders
Interventions: DRUG: Preladenant|DRUG: Placebo|DRUG: Anticholinergic agents or propanolol|DRUG: Haloperidol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Breastfeeding Position on Breastfeeding Self-efficacy, Success and Postpartum Comfort
Status: NOT_YET_RECRUITING
Conditions: Breastfeeding
Interventions: OTHER: Giving a biological breastfeeding position|OTHER: Giving a football ( armpit) position
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Atazanavir-ritonavir on the Pharmacokinetics and Toxicity of Lumefantrine
Status: COMPLETED
Conditions: Drug Interaction
Interventions: DRUG: Artemether-lumefantrine|DRUG: Atazanavir-ritonavir 300/100 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Drug-Drug Interaction Study Between Colchicine and Diltiazem ER
Status: COMPLETED
Conditions: Healthy; Adult; Volunteer; Colchicine; Pharmacokinetics; Diltiazem; Cytochrome p450 3A4; P-glycoprotein
Interventions: DRUG: Colchicine|DRUG: Diltiazem ER|DRUG: Colchicine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Evaluate the Safety and Tolerability of ONL1204 in Patients With Macula-off, Rhegmatogenous Retinal Detachment
Status: COMPLETED
Conditions: Rhegmatogenous Retinal Detachment - Macula Off
Interventions: DRUG: ONL1204|PROCEDURE: Intravitreal Injection|PROCEDURE: Collection of ocular fluids
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase ⅠStudy of the Recombinant Mycobacterium Tuberculosis Vaccine Freeze-dried
Status: COMPLETED
Conditions: Tuberculosis
Interventions: BIOLOGICAL: Placebo|BIOLOGICAL: Low dose adjuvant|BIOLOGICAL: High dose adjuvant|BIOLOGICAL: Low dose vaccine|BIOLOGICAL: High dose vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Understanding the Sleep Apnea/Insomnia Interaction
Status: COMPLETED
Conditions: Sleep Apnea Syndromes|Sleep Initiation and Maintenance Disorders
Interventions: DEVICE: CPAP|BEHAVIORAL: CBT|DEVICE: sham CPAP|BEHAVIORAL: CC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: EFFECTS OF THE MICRO REINJECTION OF AUTOLOGOUS ADIPOSE TISSUE IN THE FACE OF PATIENTS WITH SYSTEMIC SCLEROSIS
Status: UNKNOWN
Conditions: Systemic Sclerosis
Interventions: OTHER: Micro reinjection of autologus adipose tissue
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: MRI Screening for Patients With Myelodysplastic Syndrome (MDS), Who Have Received Multiple Red Blood Cell Transfusions
Status: COMPLETED
Conditions: Myelodysplastic Syndrome (MDS)
Interventions: OTHER: T2* Cardiac and Liver MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Paramedic Initiated Lisinopril For Acute Stroke Treatment
Status: COMPLETED
Conditions: Stroke
Interventions: DRUG: Lisinopril|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 6 Week Open-label Trial With Lumiracoxib 200mg o.d. in Primary Knee Osteoarthritis or Rheumatoid Arthritis
Status: COMPLETED
Conditions: Osteoarthritis|Rheumatoid Arthritis
Interventions: DRUG: Lumiracoxib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Longitudinal (Weekly) Follow-up of Active Plaques in Multiple Sclerosis With 3 Teslas Multi-modality MRI Using Diffusion, Perfusion, Venography and Proton Spectroscopy
Status: COMPLETED
Conditions: Lesions|Multiple Sclerosis
Interventions: PROCEDURE: 3T MR scanner
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Effect of Treatment of Pre-induction Hypertension on Hemodynamic Stability During Induction of General Anesthesia
Status: NOT_YET_RECRUITING
Conditions: Hypertension
Interventions: DRUG: Clevidipine|DRUG: Lactated Ringers, Intravenous
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Effects of MEDI6012 on Apolipoprotein B100 Metabolism
Status: TERMINATED
Conditions: Cardiovascular Diseases
Interventions: DRUG: MEDI6012|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy in Treating Patients With Metastatic Ovarian Cancer or Non-small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer|Neurotoxicity|Ovarian Cancer
Interventions: DRUG: amifostine trihydrate|DRUG: carboplatin|DRUG: paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Stress and Pain Self-management m-Health App for Adult Outpatients With Sickle Cell Disease
Status: RECRUITING
Conditions: Sickle Cell Disease
Interventions: BEHAVIORAL: Self-monitoring of pain, stress, and opioid use + alerts/reminders + use of YCWS. [three video banks of RDE + Support]).|BEHAVIORAL: Self-monitoring of pain, stress, and opioid use + alerts/reminders.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GetHealthy-OA: A Program to Improve Pain and Function for Patients With Knee Osteoarthritis, Obesity, and Depression
Status: WITHDRAWN
Conditions: Knee Osteoarthritis|Obese|Depression
Interventions: DRUG: Fisetin|BEHAVIORAL: GetHealthy-OA mind-body program|DRUG: Placebo oral capsule|BEHAVIORAL: Health education booklet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Medico-economic Evaluation of Subcutaneous Automatic Resorbable Staples Device
Status: COMPLETED
Conditions: ENT Surgery|Gynecological Surgery|Plastic Surgery
Interventions: DEVICE: Insorb resorbable staples|DEVICE: Monocryl resorbable wire
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Gene Therapy for Ischemic Heart Disease in Korea
Status: COMPLETED
Conditions: Ischemic Heart Disease
Interventions: BIOLOGICAL: VM202RY|BIOLOGICAL: VM202RY|BIOLOGICAL: VM202RY
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I/II Study of Intratumoral Injection of SD-101
Status: COMPLETED
Conditions: Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue|Nodal Marginal Zone B-cell Lymphoma|Recurrent Grade 1 Follicular Lymphoma|Recurrent Grade 2 Follicular Lymphoma|Recurrent Marginal Zone Lymphoma|Recurrent Small Lymphocytic Lymphoma|Splenic Marginal Zone Lymphoma
Interventions: BIOLOGICAL: Ipilimumab|DRUG: SD-101|RADIATION: Radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Teenagers: Impact of Eccentric eXercise Training on Overweight and Obesity
Status: UNKNOWN
Conditions: Adolescents (12 to 17 Years Old)|Obese (BMI>90th Percentile)
Interventions: OTHER: Cycling exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Effectiveness of a Cognitive and Physical Intervention to Reduce Head and Muscle Pain in a Large Population
Status: UNKNOWN
Conditions: Migraine|Tension Type Headache|Cervical Pain
Interventions: BEHAVIORAL: Behavioral: Cognitive, Relaxation, Exercise Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Safety and Preliminary Efficacy of MAGE-A4 TCR Gene-Modified T Cells to Treat Malignant Tumors
Status: UNKNOWN
Conditions: Malignant Solid Tumors
Interventions: BIOLOGICAL: MAGE-A4 TCR Gene-Modified T Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy and Safety of Toluedesvenlafaxine Hydrochloride Extended-release Tablets in Somatic Symptoms of Depression
Status: NOT_YET_RECRUITING
Conditions: Somatic Symptom
Interventions: DRUG: toludesvenlafaxine hydrochloride sustained-release tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Liver Test Study of Using JKB-122 in Autoimmune Hepatitis (AIH) Patients Who Are Refractory or Intolerant to Current Therapies
Status: COMPLETED
Conditions: Autoimmune Hepatitis
Interventions: DRUG: JKB-122
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rapid Maxillary Expansion and Protraction by Expander Differential Opening EDO in Cleft Lip and Palate Patients
Status: UNKNOWN
Conditions: Cleft Lip and Palate
Interventions: DEVICE: expander with deferential opening and petit face mask
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lenvatinib and Capecitabine in Patients With Advanced Malignancies
Status: WITHDRAWN
Conditions: Advanced Cancer|Malignant Neoplasm of Breast|Malignant Neoplasms of Bone and Articular Cartilage|Malignant Neoplasms of Digestive Organs|Malignant Neoplasms of Eye Brain and Other Parts of Central Nervous System|Malignant Neoplasms of Female Genital Organs|Malignant Neoplasms of Ill-defined Secondary and Unspecified Sites|Malignant Neoplasms of Independent (Primary) Multiple Sites|Malignant Neoplasms of Lip Oral Cavity and Pharynx|Malignant Neoplasms of Male Genital Organs|Malignant Neoplasms of Mesothelial and Soft Tissue|Malignant Neoplasms of Respiratory and Intrathoracic Organs|Malignant Neoplasms of Thyroid and Other Endocrine Glands|Malignant Neoplasms of Urinary Tract
Interventions: DRUG: Lenvatinib|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transcranial Photobiomodulation as a Therapy for Patients With Parkinson's Disease: Relationship Between Pain and Brain Functional Connectivity (FBM)
Status: RECRUITING
Conditions: Parkinson Disease|Pain|Photobiomodulation
Interventions: RADIATION: Photobiomodulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study in Participants With Diabetic Peripheral Neuropathic Pain in China
Status: COMPLETED
Conditions: Diabetic Neuropathy, Painful
Interventions: DRUG: Duloxetine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Improving Knowledge in Heart Failure Inpatient With Therapeutic Education
Status: TERMINATED
Conditions: Heart Failure With Reduced Ejection Fraction|Heart Failure; With Decompensation|Pharmacist-Patient Relations|Medication Adherence|Knowledge, Attitudes, Practice
Interventions: OTHER: Patient therapeutic education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Open Eye Corneal Swelling With Daily Disposable Contact Lenses and no Lens Wear
Status: COMPLETED
Conditions: Corneal Swelling
Interventions: DEVICE: etafilcon A with Lacreon|DEVICE: etafilcon A with Lacreon with print|DEVICE: etafilcon A with print|DEVICE: Spectacles (habitual)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Efficacy of Two Probiotic Strains for Irritable Bowel Syndrome
Status: COMPLETED
Conditions: Irritable Bowel Syndrome
Interventions: DIETARY_SUPPLEMENT: Bifidobacterium longum R0175|DIETARY_SUPPLEMENT: Lactobacillus paracasei HA-196|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: ChoicesPlus: Reducing Alcohol- and Tobacco-Exposed Pregnancy
Status: COMPLETED
Conditions: Alcohol Use|Smoking|Contraception
Interventions: BEHAVIORAL: Choices Plus|BEHAVIORAL: Information
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Trial of Cabozantinib (XL184) and Gemcitabine in Advanced Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DRUG: CABOZANTINIB|DRUG: gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High Intensity vs Low Intensity Resistive Exercise In Patient With Upper Extremity Lymphedema
Status: COMPLETED
Conditions: Lymphedema
Interventions: OTHER: High intensity resistive exercise|OTHER: Low intensity resistive exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Interface With/Without Oral Appliance of Sleep Apnea Treatment
Status: TERMINATED
Conditions: Obstructive Sleep Apnea
Interventions: DEVICE: Nasal mask and oral appliance vs oro-nasal mask during autoCPAP therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasound Guided A1 Pulley Release For The Treatment of Trigger Finger
Status: COMPLETED
Conditions: Surgical Release of Ai Pulley Trigger Finger
Interventions: PROCEDURE: Surgical release A1 pulley for Trigger finger of the hand
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Safety and Tolerability of a Novel Malathion Formulation in Patients 2 Years and Older With Head Lice
Status: COMPLETED
Conditions: Pediculosis
Interventions: DRUG: Malathion gel 0.5%|DRUG: Permethrin 1% rinse
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing Combinations of Targeted Drugs for Advanced Non-Small Cell Lung Cancer That Has EGFR and MET Gene Changes (A Lung-MAP Treatment Trial)
Status: RECRUITING
Conditions: Recurrent Lung Non-Small Cell Carcinoma|Stage IV Lung Cancer AJCC v8
Interventions: PROCEDURE: Biospecimen Collection|DRUG: Capmatinib|PROCEDURE: Computed Tomography|PROCEDURE: Magnetic Resonance Imaging|DRUG: Osimertinib|BIOLOGICAL: Ramucirumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Study on Intensive Early Rheumatoid Arthritis Treatment
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: adalimumab, plus prednisone|DRUG: adalimumab plus placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transplantation of Autologous Bone Marrow or Leukapheresis-Derived Stem Cells for Treatment of Spinal Cord Injury
Status: UNKNOWN
Conditions: Spinal Cord Injury
Interventions: BIOLOGICAL: Stem Cell Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Hydroxychloroquine and Azithromycin for Patients With Moderate to Severe COVID-19
Status: SUSPENDED
Conditions: COVID-19
Interventions: DRUG: Hydroxychloroquine Sulfate|DRUG: Azithromycin Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Glucagon-like Peptide-2 Mediated Secretion of Stored Enteral Lipids
Status: COMPLETED
Conditions: Hyperlipidemias
Interventions: DRUG: Teduglutide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Probiotics in the Treatment of Irritable Bowel Syndrome
Status: COMPLETED
Conditions: Irritable Bowel Syndrome
Interventions: DRUG: Probiotic|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Oral Iron Supplementation on Vaccine Response in Iron Deficient Kenyan Women
Status: RECRUITING
Conditions: Iron Deficiency Anemia
Interventions: DIETARY_SUPPLEMENT: Oral iron supplementation (pre-treatment)|BIOLOGICAL: COVID-19 vaccine|BIOLOGICAL: MenACWY vaccine|DIETARY_SUPPLEMENT: Oral iron supplementation (simultaneous treatment)|BIOLOGICAL: Typhim Vi vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Operative Treatment Of Metatarsalgia: Triple Weil Osteotomy Or Distal Metatarsal Minimal Invasive Osteotomy (DMMO)?
Status: UNKNOWN
Conditions: Metatarsalgia
Interventions: PROCEDURE: Triple Weil´s Osteotomy|PROCEDURE: Distal metatarsal minimally invasive osteotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Feasibility of Arrhythmia Ablation Using the Amigo Remote Robotic System as Compared With Manual Ablation
Status: UNKNOWN
Conditions: Arrhythmias
Interventions: DEVICE: Amigo|DEVICE: Manual ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cytokine and MMP Levels in Gingival Crevicular Fluid in the Treatment of Localized Gingival Recessions
Status: COMPLETED
Conditions: Gingival Recession
Interventions: PROCEDURE: Connective tissue graft|PROCEDURE: Platelet Rich Fibrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Multiple Doses of JNJ-38431055 in Volunteers With Type 2 Diabetes Mellitus
Status: TERMINATED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: JNJ-38431055; Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Opt-IN: Optimization of Remotely Delivered Intensive Lifestyle Treatment for Obesity
Status: COMPLETED
Conditions: Weight Loss
Interventions: BEHAVIORAL: 12 Telephone Coaching Sessions|BEHAVIORAL: 24 Telephone Coaching Sessions|BEHAVIORAL: Report to Primary Care Physician|BEHAVIORAL: Text Messages|BEHAVIORAL: Recommendations to use meal replacements|BEHAVIORAL: Buddy Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Closed-Loop Deep Brain Stimulation for Refractory Chronic Pain
Status: RECRUITING
Conditions: Spinal Cord Injuries|Nerve Injury|Pain, Postoperative|Post Herpetic Neuralgia|Complex Regional Pain Syndromes|Post-Stroke Pain|Post Radiation Brain Injury|Post Radiation Plexopathy|Nerve Root Avulsion
Interventions: DEVICE: Medtronic Summit RC+S or Percept RC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Are Standard Dosing Regimens of Piperacillin-Tazobactam Suitable in Critically Ill Patients With Open Abdomen and Negative Pressure Wound Therapy? A Population Pharmacokinetic Study.
Status: COMPLETED
Conditions: Laparotomy|Critical Illness|Piperacillin, Tazobactam Drug Combination
Interventions: PROCEDURE: Blood sampling (T0, inclusion)|PROCEDURE: other samplings (T1)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Transit Time and Bacterial Overgrowth Using SmartPill Capsule
Status: TERMINATED
Conditions: Small Bowel Bacterial Overgrowth|Gastrointestinal Diseases|Stomach Diseases|Digestive System Diseases
Interventions: DRUG: Xifaxan|DEVICE: SmartPill|PROCEDURE: Lactulose hydrogen breath test (H_2BT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Safety, Pharmacokinetics and Efficacy Study of MAU868 for the Treatment of BK Viremia in Kidney Transplant Recipients
Status: COMPLETED
Conditions: BK Virus Infection
Interventions: DRUG: MAU868|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT