pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Video Capsule Endoscopy Versus Colonoscopy in Patients With Melena and Negative Upper Endoscopy
Status: TERMINATED
Conditions: Gastrointestinal Hemorrhage
Interventions: PROCEDURE: Video Capsule Endoscopy|PROCEDURE: Colonoscopy|DEVICE: 1.0 X 2.5 cm 'pill' containing a camera
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Phase II Pharmacokinetics Study of Humalog and Humulin-R With and Without rHuPH20 in Type 1 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus
Interventions: DRUG: Humalog|DRUG: Humulin-R|DRUG: Recombinant human hyaluronidase PH20 (rHuPH20)|OTHER: Liquid meal
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Two Inhalation Formulations Containing Budesonide 200 µg
Status: COMPLETED
Conditions: Allergy
Interventions: DRUG: Budesonida Pulmictan® 200 µg|DRUG: Budesonide 200 µg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Capsule Endoscopy Crohn's Disease Activity Index - Validation Multi Center Study
Status: COMPLETED
Conditions: Crohn's Disease
Interventions: DEVICE: Given® Diagnostic System including PillCamTM SB Capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Identify Predictors That Distinguish Between Tofacitinib Responders and Non-responders Based on Genotype and Cellular and Molecular Profiles From Pinch Biopsies, Blood and Stool Samples
Status: COMPLETED
Conditions: Ulcerative Colitis
Interventions: DIAGNOSTIC_TEST: GWAS analysis by Illumina BeadChip
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Subcutaneous Injection of Sodium Thiosulfate for Ectopic Calcifications or Ossifications. A Pilot Study
Status: RECRUITING
Conditions: Systemic Sclerosis|Dermatomyositis|iPPSD2
Interventions: DRUG: STS
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mycophenolate Mofetil Versus Intravenous Cyclophosphamide Pulses in the Treatment of Crescentic IgA Nephropathy
Status: COMPLETED
Conditions: IGA Nephropathy
Interventions: DRUG: Mycophenolate mofetil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Gut Microbiome in Women With Polycystic Ovary Syndrome
Status: COMPLETED
Conditions: PCOS|Obesity|Metabolic Syndrome
Interventions: DIETARY_SUPPLEMENT: dietary advice plus myo-inositol and folic acid|DRUG: dietary advice plus Liraglutide Pen Injector
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Wear of Enamel Antagonist to Two Different Types of Monolithic Zirconia Monolithic Zirconia
Status: UNKNOWN
Conditions: Wear, Occlusal
Interventions: PROCEDURE: Newly Introduced Gradient Monolithic Zirconia|PROCEDURE: Full Strength Monolithic Zirconia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dyadic Yoga Intervention in Improving Physical Performance and Quality of Life in Patients With Stage I-IV Non-small Cell Lung or Esophageal Cancer Undergoing Radiotherapy and Their Caregivers
Status: RECRUITING
Conditions: Esophageal Carcinoma|Lung Non-Small Cell Carcinoma|Stage I Lung Cancer AJCC v8|Stage IA1 Lung Cancer AJCC v8|Stage IA2 Lung Cancer AJCC v8|Stage IA3 Lung Cancer AJCC v8|Stage IB Lung Cancer AJCC v8|Stage II Lung Cancer AJCC v8|Stage IIA Lung Cancer AJCC v8|Stage IIB Lung Cancer AJCC v8|Stage III Lung Cancer AJCC v8|Stage IIIA Lung Cancer AJCC v8|Stage IIIB Lung Cancer AJCC v8|Stage IIIC Lung Cancer AJCC v8|Stage IV Lung Cancer AJCC v8|Stage IVA Lung Cancer AJCC v8|Stage IVB Lung Cancer AJCC v8
Interventions: OTHER: Educational Intervention|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration|PROCEDURE: Yoga
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Prospective Study on Oncologic Cerebral Imagery Contribution by 18F-FDOPA Position Emission Tomography (PET)
Status: COMPLETED
Conditions: Glioma|Cerebral Metastases
Interventions: OTHER: PET 18FDOPA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of Different Doses of Megestrol Acetate in Patients With AIDS Who Have Anorexia and Malnutrition
Status: COMPLETED
Conditions: Anorexia|Cachexia|HIV Infections
Interventions: DRUG: Megestrol acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Study to Investigate the Effect of Inhaled Tiotropium Bromide on Neurokinin-A Induced Bronchoconstriction in Patients With Mild-to-moderate Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Administration of inhaled tiotropium bromide|DRUG: Administration of placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Determine the Safety and Efficacy of NT-501 in Macular Telangiectasia Type 2 - Protocol A
Status: COMPLETED
Conditions: Macular Telangiectasia Type 2
Interventions: COMBINATION_PRODUCT: NT-501|PROCEDURE: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Efficacy and Safety of Epoetin Alfa Administered Weekly in Patients With Gastric or Rectal Cancers Undergoing a Treatment Plan of Preoperative Chemotherapy and Radiation Therapy, Followed by Surgery
Status: COMPLETED
Conditions: Stomach Neoplasms|Rectal Neoplasms
Interventions: DRUG: epoetin alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: WEST-KOaST Study: WES Analysis of Testicular Cancer Patientsand Their First-degree Family Members
Status: NOT_YET_RECRUITING
Conditions: Testicular Cancer
Interventions: GENETIC: Analysis of biological samples of saliva from testicular cancer patients and from their first-degree family members
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Pilot Study for the Evaluation of the Safety and Performance of the RenaSense System in Hospitalized Acute Decompensated Heart Failure Patients
Status: UNKNOWN
Conditions: Heart Decompensation|Heart Failure, Congestive|Renal Insufficiency
Interventions: DEVICE: RenaSense Stimulation|DEVICE: RenaSense Sham Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: NBI-98854 for the Treatment of Tardive Dyskinesia in Subjects With Schizophrenia or Schizoaffective Disorder
Status: COMPLETED
Conditions: Tardive Dyskinesia
Interventions: DRUG: NBI-98854|DRUG: NBI-98854|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II Study of Stereotypes and Mental Retardation: Neurobiological Basis
Status: SUSPENDED
Conditions: Stereotyped Behavior|Mental Retardation
Interventions: DRUG: bromocriptine|DRUG: sertraline hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: To Evaluate Efficacy and Tolerability of Sodium Bicarbonate Toothpaste and Its Effect on Opportunistic or Resistant Organisms
Status: COMPLETED
Conditions: Oral Hygiene
Interventions: DRUG: Sodium bicarbonate and sodium fluoride|DRUG: Sodium fluoride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Carnosine on Diabetes and Cardiovascular Risk Factors
Status: COMPLETED
Conditions: Metabolic Diseases, Type 2 Diabetes, Cardiovascular Disease
Interventions: DIETARY_SUPPLEMENT: Carnosine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Impact of Splenic Artery Ligation in LDLT for Patients With Portal Hypertension
Status: UNKNOWN
Conditions: Living Donor Liver Transplantation
Interventions: PROCEDURE: splenic artery ligation|PROCEDURE: No intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Sirolimus and Mycophenolate Mofetil in Preventing GVHD in Patients With Hematologic Malignancies Undergoing HSCT
Status: TERMINATED
Conditions: Adult Hodgkin Lymphoma|Adult Myelodysplastic Syndrome|Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive|Childhood Chronic Myelogenous Leukemia, BCR-ABL1 Positive|Childhood Hodgkin Lymphoma|Childhood Myelodysplastic Syndrome|Chronic Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive|Myelofibrosis|Primary Myelofibrosis|Recurrent Adult Acute Lymphoblastic Leukemia|Recurrent Adult Acute Myeloid Leukemia|Recurrent Adult Non-Hodgkin Lymphoma|Recurrent Childhood Acute Lymphoblastic Leukemia|Recurrent Childhood Acute Myeloid Leukemia|Recurrent Childhood Non-Hodgkin Lymphoma|Recurrent Chronic Myelogenous Leukemia, BCR-ABL1 Positive|Refractory Chronic Myelogenous Leukemia, BCR-ABL1 Positive|Refractory Non-Hodgkin Lymphoma
Interventions: PROCEDURE: Allogeneic Hematopoietic Stem Cell Transplantation|OTHER: Laboratory Biomarker Analysis|DRUG: Mycophenolate Mofetil|DRUG: Sirolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Clinical Trial Evaluating the Effect of BCG Vaccination on the Incidence and Severity of SARS-CoV-2 Infections Among Healthcare Professionals During the COVID-19 Pandemic in Poland
Status: UNKNOWN
Conditions: Covid19|BCG Vaccination Reaction|SARS-CoV Infection
Interventions: DRUG: BCG-10 vaccine|DRUG: 0.9% saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Minoxidil in Children With Williams-Beuren Syndrome
Status: COMPLETED
Conditions: Williams Beuren Syndrome
Interventions: DRUG: Minoxidil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Tacrolimus in Combination With Ripertamab in the Initial Treatment of Patients With MCD
Status: NOT_YET_RECRUITING
Conditions: Minimal Change Disease
Interventions: DRUG: Supportive care+Prednisone|DRUG: Supportive care+Tacrolimus+Ripertamab|DRUG: Supportive care+Ripertamab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 1/2-MC4R Genotype and Pediatric Antipsychotic Drug- Induced Weight Gain
Status: TERMINATED
Conditions: High Risk MC4R Genotype|Low Risk MC4R Genotype|One Week or Less Antipsychotic Lifetime Exposure
Interventions: DRUG: Ziprasidone|DRUG: aripiprazole, quetiapine, or risperidone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Chemoradiation and Tetrathiomolybdate (TM) in Patients With Esophageal Carcinoma
Status: COMPLETED
Conditions: Esophageal Carcinoma
Interventions: DRUG: Tetrathiomolybdate (TM)|PROCEDURE: Radiation|PROCEDURE: Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Methylphenidate on Cancer-related Cognitive Impairment
Status: TERMINATED
Conditions: Breast Cancer Female|Cancer-Related Condition
Interventions: DRUG: Methylphenidate HCl 10Mg SR|DRUG: Placebo Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: To Compare the Incidence of POST Between a TaperGuard ETT and Cylindrical-shaped ETT Under High Cuff Pressure
Status: UNKNOWN
Conditions: Postoperative Complications
Interventions: OTHER: TaperGuard ETT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of Sevoflurane, Propofol, and Sevoflurane Plus Propofol for Maintenance of Anaesthesia
Status: COMPLETED
Conditions: Laparoscopic Surgery|Hysteroscopic Surgery
Interventions: DRUG: Propofol for maintenance|DRUG: Sevoflurane|DRUG: Sevoflurane+Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Guided Fluid-balance Optimization With Mini-fluid chALlenge During Septic Shock
Status: COMPLETED
Conditions: Septic Shock
Interventions: OTHER: Minifluid challenge|OTHER: Usual practice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy Plus Ofatumumab Followed by G-CSF for Mobilization of Peripheral Blood Stem Cells in Patients With Non-Hodgkin's Lymphomas
Status: COMPLETED
Conditions: Lymphoma
Interventions: DRUG: Ofatumumab|DRUG: Ifosfamide|DRUG: Etoposide|DRUG: Mesna|DRUG: G-CSF|PROCEDURE: Stem Cell Collection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BNP (Nesiritide) vs. Placebo to Protect Kidney Function in Patients Undergoing Heart Bypass Surgery.
Status: COMPLETED
Conditions: Acute Kidney Failure
Interventions: DRUG: Neseritide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of ALTY-0501 for the Treatment of Dry Eye Administered 4 Times a Day for a 56 Day Period
Status: COMPLETED
Conditions: Dry Eye
Interventions: DRUG: doxycycline|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: A Conditioning Paradigm to Increase Affinity for Sacredness of Life
Status: COMPLETED
Conditions: Suicidal Ideation|Suicide, Attempted|Suicide and Self-harm|Non-suicidal Self-injury
Interventions: BEHAVIORAL: TEC-Sacredness|BEHAVIORAL: TEC-Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study of Ataluren for Previously Treated Participants With Nonsense Mutation Duchenne/Becker Muscular Dystrophy (nmDBMD) in Europe, Israel, Australia, and Canada
Status: COMPLETED
Conditions: Duchenne Muscular Dystrophy|Becker Muscular Dystrophy|Dystrophinopathy
Interventions: DRUG: Ataluren
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study for Monthly Methoxy Polyethylene Glycol-Epoetin Beta Treatment in Patients With Chronic Renal Anaemia
Status: TERMINATED
Conditions: Anemia
Interventions: DRUG: methoxy polyethylene glycol-epoetin beta [Mircera]
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acute Application of Antibiotic Powder in Open Fracture Wounds
Status: COMPLETED
Conditions: Fractures, Open|Wounds and Injuries--Infections|Anti-Bacterial Agents|Fractures, Bone|Extremity Fracture Lower|Extremity Fractures Upper
Interventions: DRUG: Vancomycin|DRUG: Tobramycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Oral Potentially Malignant Disorders: Comparison Between Surgical Treatment and Wait and See Approach
Status: RECRUITING
Conditions: Leukoplakia, Oral
Interventions: PROCEDURE: Surgical excision of the lesion|OTHER: Wait and see approach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Transcranial Direct Current Stimulation and the Interaction Between Chronic Pain and the Intestinal Epithelial Barrier in Patients With Chronic Inflammatory Bowel Diseases (IBD)
Status: UNKNOWN
Conditions: Inflammatory Bowel Diseases
Interventions: DEVICE: Sham OR active Transcranial direct current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of A/H1N1-SOIV (Swine Flu) Vaccine With and Without Adjuvant in Children, Adolescents and Adults (3 to 64 Years)
Status: COMPLETED
Conditions: Novel 2009 Influenza H1N1
Interventions: BIOLOGICAL: MF59-eH1N1_f|BIOLOGICAL: eH1N1_f
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of ASP8273 in Subjects With Non-small Cell Lung Cancer (NSCLC) Harboring Epidermal Growth Factor Receptor (EGFR) Mutations
Status: TERMINATED
Conditions: Non-small Cell Lung Cancer (NSCLC)|Epidermal Growth Factor Receptor (EGFR) Mutations
Interventions: DRUG: naquotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Complementary Medicine Techniques (Therapeutic Touch and Hypno Analgesia) on the Term of Delivery of Patients Hospitalized for Preterm Labor (Hypnorelax)
Status: COMPLETED
Conditions: Premature Birth
Interventions: OTHER: Touching relaxant|OTHER: Hypnoses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Unilateral Biportal Endoscopy Lumbar Interbody Fusion (ULIF) Versus Posterior Lumbar Interbody Fusion (PLIF) in Management of Single Level Lumbar Degenerative Disease: A Retrospective Study
Status: COMPLETED
Conditions: Lumbar Degenerative Disease
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Pilot Study of Single Fraction Stereotactic Body Radiation Therapy (SBRT) in Central Non-Small Cell Lung Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Non Small Cell Lung Cancer
Interventions: RADIATION: SBRT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Evaluation of Effectiveness of Hall Technique and Resin Modified Glass Ionomer Cement in Controlling Occlusoproximal Caries in Primary Molars in Children
Status: UNKNOWN
Conditions: Dental Caries
Interventions: PROCEDURE: Hall technique|PROCEDURE: RMGIC restoration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ventilator Weaning Outcome Between NIV-NAVA and Nasal CPAP (or IMV ) Modes in Premature Neonates
Status: UNKNOWN
Conditions: Respiratory Distress Syndrome in Premature Infant
Interventions: PROCEDURE: NIV-NAVA|PROCEDURE: Nasal CPAP or NIMV mode
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of the Effect NT-I7 on CD4 Counts in Patients With High Grade Gliomas
Status: TERMINATED
Conditions: Lymphopenia|Malignant Glioma
Interventions: OTHER: Laboratory Biomarker Analysis|BIOLOGICAL: NT-I7|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Use of Red Light Emitting Diode (LED) and Polydioxanone Thread in Glabellar Wrinkles
Status: COMPLETED
Conditions: Skin Wrinkling|Edema
Interventions: DEVICE: Photobiomodulation|PROCEDURE: PDO thread
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Preliminary Antitumor Activity, Safety and Tolerability of Tislelizumab in Combination With Lenvatinib for Hepatocellular Carcinoma
Status: COMPLETED
Conditions: Hepatocellular Carcinoma|Unresectable Hepatocellular Carcinoma|Metastatic Hepatocellular Carcinoma
Interventions: DRUG: Lenvatinib|DRUG: Tislelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Safety, Reactogenicity, and Immune Response of GVGH iNTS-TCV Vaccine Against Invasive Nontyphoidal Salmonella and Typhoid Fever
Status: RECRUITING
Conditions: Salmonella Infections
Interventions: BIOLOGICAL: Invasive nontyphoidal Salmonella-typhoid conjugate vaccine (iNTS-TCV) low dose|BIOLOGICAL: Invasive nontyphoidal Salmonella-generalized modules for membrane antigens vaccine (iNTS-GMMA) low dose|BIOLOGICAL: Typhoid conjugate vaccine (TCV) low dose|BIOLOGICAL: Invasive nontyphoidal Salmonella-typhoid conjugate vaccine (iNTS-TCV) full dose|BIOLOGICAL: Invasive nontyphoidal Salmonella-generalized modules for membrane antigens vaccine (iNTS-GMMA) full dose|BIOLOGICAL: Typhoid conjugate vaccine (TCV) full dose|BIOLOGICAL: GSK's Meningococcal A, C, Y and W-135 conjugate vaccine|COMBINATION_PRODUCT: GSK's Tetanus toxoid, reduced diphtheria toxoid and acellular pertussis vaccine|COMBINATION_PRODUCT: Sanofi Pasteur's Typhoid Vi polysaccharide vaccine|DRUG: Placebo|OTHER: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: MAFLD-simplified Definition as an Optimized Risk Stratification Tool for Predicting Metabolic Outcomes
Status: COMPLETED
Conditions: Metabolic Associated Fatty Liver Disease
Interventions: DIAGNOSTIC_TEST: the differences of MAFLD and MAFLD-simplified definitions were compared in predicting metabolic diseases
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Promotion of Egg and Eggshell Powder Consumption Improve Nutritional Status of Children in Halaba Ethiopia
Status: COMPLETED
Conditions: Thinness|Food Habits|Health Knowledge, Attitudes, Practices
Interventions: BEHAVIORAL: Promotion of chicken eggs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate a Study Drug, DCB-BO1202, for Alleviating Liver Fibrosis in Liver Cancer Patients
Status: WITHDRAWN
Conditions: Liver Fibrosis|HEPATITIS B CHRONIC|Hepatocellular Carcinoma
Interventions: DRUG: DCB-BO1202|DRUG: Placebo|DRUG: DCB-BO1202+Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Behavioural and Electrophysiological Effects of rTMS in Functional Neurological Disorders
Status: COMPLETED
Conditions: Functional Neurological Disorder
Interventions: DEVICE: MagStim Rapid2 Transcranial Magnetic Simulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Self-regulation of Prefrontal Cortex During Emotional Cognitive Control
Status: COMPLETED
Conditions: Healthy Volunteers|Cognitive Function
Interventions: OTHER: Real-time functional magnetic resonance neurofeedback (rtfMRI-nf)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Maternal-Infant Exercise Program on Body Composition, Stress, Fatigue, and Attachment in Postpartum Women
Status: UNKNOWN
Conditions: Postpartum|Body Composition|Stress|Fatigue|Attachment
Interventions: OTHER: Maternal-Infant Exercise Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Superselective Adrenal Arterial Embolization for Resistant Hypertension
Status: NOT_YET_RECRUITING
Conditions: Resistant Hypertension
Interventions: PROCEDURE: SAAE|DRUG: traditional triple antihypertensive treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison Of Reduced DAPT Followed by P2Y12 Inhibitor Monotherapy With Prasugrel vs stAndard Regimen in STEMI Patients
Status: RECRUITING
Conditions: ST Elevated Myocardial Infarction|Dual Antiplatelet Therapy
Interventions: DRUG: Prasugrel based short DAPT|DRUG: Prasugrel based standard DAPT|DEVICE: OCT guided revascularization|DEVICE: Angio guided revascularization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Perfusion Estimation For Optimal Treatment Strategy in Chronic Coronary Syndrome
Status: RECRUITING
Conditions: Chronic Coronary Syndrome|Myocardial Ischemia|Stable Angina|Coronary Artery Disease
Interventions: OTHER: Optimization of guideline-directed medical therapy|DIAGNOSTIC_TEST: Immediate referral for invasive coronary angiography|DIAGNOSTIC_TEST: 3-months delayed referral for invasive coronary angiography|OTHER: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Influence by Dietary Human Milk Oligosaccharide in Low Birth Weight Infants
Status: COMPLETED
Conditions: Low Birth Weight Infants
Interventions: DIETARY_SUPPLEMENT: Infant formula with Human Milk Oligosaccharide|DIETARY_SUPPLEMENT: Infant formula without Human Milk Oligosaccharide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Etude Tomos- Apport de la Tomosynthèse Dans le Bilan d'Extension locorégional préthérapeutique d'Une Tumeur du Sein : Recherche de multicentricité Tomos Study- Contribution of Tomosynthesis In Locoregional Pretherapeutic Staging of a Breast Tumor: Multicentricity Search
Status: TERMINATED
Conditions: Mammary Tumor
Interventions: OTHER: Evaluation of the Tomosynthesis|OTHER: Avaluation of a medical device: the tomosynthesis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy and Safety of Short Course Therapy With Peginterferon Alpha-2b (PEG-IFN Alfa-2b) and Ribavirin (RBV) for Chronic Hepatitis C (Genotype 4) Participants Achieving a Rapid Virological Response at Week 4 of Treatment (MK-8908B-059)
Status: TERMINATED
Conditions: Hepatitis C, Chronic
Interventions: DRUG: PEG-IFN alfa-2b|DRUG: ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of ACT-541468 in Adult Subjects With Insomnia Disorder
Status: COMPLETED
Conditions: Insomnia Disorder
Interventions: DRUG: ACT-541468 5 mg|DRUG: ACT-541468 10 mg|DRUG: ACT-541468 25 mg|DRUG: Zolpidem|DRUG: Placebo 1|DRUG: Placebo 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Trial of the Effect of Vorinostat and AGS-004 on Persistent HIV-1 Infection
Status: TERMINATED
Conditions: HIV-1 Infection
Interventions: DRUG: Vorinostat|BIOLOGICAL: AGS-004
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Women Focused Encounters for Resilience Independence Strength and Eudaimonia
Status: RECRUITING
Conditions: HIV Infections|Substance Use|Trauma|Medication Adherence
Interventions: BEHAVIORAL: Acceptance and Commitment Therapy (ACT)|BEHAVIORAL: Body weight circuit training|BEHAVIORAL: Empathetic social support|OTHER: Control - list of resources
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of High-dose Intravenous Immunoglobulin Therapy for Hyperbilirubinemia Due Rh Hemolytic Disease
Status: COMPLETED
Conditions: Hyperbilirubinemia|Erythroblastosis, Fetal
Interventions: DRUG: Intravenous Immunoglobulin|DRUG: Normal saline solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study Evaluating the Efficiency and the Tolerance of the PDT in the Treatment of Epidermal Dysplasia for Patients Affected by Hereditary DEB
Status: WITHDRAWN
Conditions: Dystrophic Epidermolysis Bullosa
Interventions: PROCEDURE: Photodynamic therapy (PDT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of a Self-Supporting Nasopharyngeal Airway in Hypotonia
Status: COMPLETED
Conditions: Sleep Apnea, Obstructive|Hypotonia|Child, Only
Interventions: DEVICE: ssNPA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Connect 'n Unite: Couples-Based HIV/STI Prevention for Drug-Involved, Black MSM
Status: COMPLETED
Conditions: HIV|Sexually Transmitted Infections
Interventions: BEHAVIORAL: CNU Intervention|BEHAVIORAL: WP Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Investigation of the Effect of White Noise Listening on Pain and Comfort During Invasive Interventions in Newborns
Status: COMPLETED
Conditions: Pain, Acute|Child Behavior|Newborn
Interventions: BEHAVIORAL: invasive interventions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Molecular Response to Custom Manual Physiotherapy Treatment of Fibromyalgia & Chronic Fatigue Syndrome (CFS)
Status: COMPLETED
Conditions: Fibromyalgia (FM)|Chronic Fatigue Syndrome (CFS)
Interventions: PROCEDURE: Manual Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating AI-Gatekeeper Software in Coronary Artery Stenosis Screening: A Multicenter RCT
Status: RECRUITING
Conditions: Coronary Artery Disease|Diagnosis
Interventions: DIAGNOSTIC_TEST: Assisted by the AI-Gatekeeper software group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Intra-luminal Radiofrequency Ablation for Inoperable Malignant Biliary Stenosis
Status: COMPLETED
Conditions: Liver Cancer|Bile Duct Cancer|Pancreatic Cancer
Interventions: DEVICE: 'Intra-luminal radiofrequency ablation (Habib EndoHPB)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Thalidomide, Prednisone, and Cyclophosphamide in Treating Patients With Myelofibrosis and Myeloid Metaplasia
Status: COMPLETED
Conditions: Chronic Myeloproliferative Disorders|Secondary Myelofibrosis
Interventions: DRUG: cyclophosphamide|DRUG: prednisone|DRUG: thalidomide|OTHER: immunohistochemistry staining method|OTHER: laboratory biomarker analysis|PROCEDURE: biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Pharmacodynamic Effects of Unfractionated Heparin (UFH) in Healthy Volunteers With and Without Bendavia
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Unfractionated heparin (UFH)|DRUG: Bendavia|DRUG: Saline (0.9%, sterile, for infusion)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Clinical Study to Assess the Long-term Safety, Tolerability, and Efficacy of Macitentan in Subjects With Eisenmenger Syndrome
Status: TERMINATED
Conditions: Pulmonary Arterial Hypertension
Interventions: DRUG: Macitentan 10 mg tablet, once daily.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pharmacokinetic Study of a Novel Nutritional Product on Healthy Men and Women
Status: NOT_YET_RECRUITING
Conditions: Healthy Aging
Interventions: DIETARY_SUPPLEMENT: Nutritional supplement|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of the Efficacy of Inflexal V With a Commercially Available Influenza Vaccine in Young Children
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Inflexal V|BIOLOGICAL: Inflexal V|BIOLOGICAL: Agrippal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Molecular Detection of Advanced Neoplasia in Pancreatic Cysts
Status: RECRUITING
Conditions: Pancreas Cyst
Interventions: DIAGNOSTIC_TEST: Blood, stool, pancreatic juice and cyst fluid collection|PROCEDURE: Pancreatic Surgery|PROCEDURE: Endoscopy Exam
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Double-masked Study of PG324 Ophthalmic Solution in Patients With Glaucoma or Ocular Hypertension
Status: COMPLETED
Conditions: Open-angle Glaucoma|Ocular Hypertension
Interventions: DRUG: PG324 Ophthalmic Solution 0.02%/0.005%|DRUG: Netarsudil (AR-13324) Ophthalmic Solution 0.02%|DRUG: Latanoprost Ophthalmic Solution 0.005%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Does Postoperative Gabapentin Reduce Pain, Opioid Consumption and Anxiety and Have a Positive Effect on Health Related Quality of Life After Radical Prostatectomy?
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: Gabapentin|DRUG: Placebo Sugar Pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Standardization of Ambulance Equipment
Status: UNKNOWN
Conditions: Safety Issues
Interventions: PROCEDURE: Administration of oxygen|PROCEDURE: Administration of drug in a nebulizer|PROCEDURE: Securing intravenous line|PROCEDURE: Administration of IV drug|PROCEDURE: Needle decompression of tension pneumothorax
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Hyperbaric Oxygen (HBO) on Blood Count Recovery After Autologous Hematopoietic Stem Cell (HSPC) Transplant for Multiple Myeloma
Status: COMPLETED
Conditions: Myeloma
Interventions: BIOLOGICAL: Hyperbaric Oxygen Therapy|OTHER: No Hyperbaric Oxygen Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Melatonin in Patients With Low Anterior Resection Syndrome
Status: ACTIVE_NOT_RECRUITING
Conditions: Low Anterior Resection Syndrome
Interventions: DRUG: Melatonin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Sublingual Immunotherapy (SLIT) to Treat House Dust Mite Allergic Rhinitis
Status: COMPLETED
Conditions: Allergic Rhinitis
Interventions: DRUG: 300 IR house dust mites allergen extract tablet|DRUG: 500 IR house dust mites allergen extract tablet|DRUG: Placebo tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Submucosal Cryotherapy on Postoperative Endodontic Pain
Status: COMPLETED
Conditions: Post-endodontic Pain
Interventions: PROCEDURE: Cryotherapy|PROCEDURE: Diclofenac sodium|PROCEDURE: Dexamethasone sodium phosphate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating the Safety and Efficacy of Fixed-dose Once-daily Oral Aripiprazole in Children and Adolescents With Tourette's Disorder
Status: COMPLETED
Conditions: Tourette's Disorder|Tic Disorder
Interventions: DRUG: Aripiprazole|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Use of Flowable Resin Composite Stent in Reduction of Donor Site Morbidity After Free Gingival Graft Harvesting
Status: RECRUITING
Conditions: Free Gingival Graft
Interventions: DEVICE: Flowble resin composite stent|DEVICE: periodontal pack
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Efficacy and Safety of Intravenous Cefiderocol (S-649266) Versus Imipenem/Cilastatin in Complicated Urinary Tract Infections
Status: COMPLETED
Conditions: Urinary Tract Infections
Interventions: DRUG: Cefiderocol|DRUG: Imipenem/cilastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact on the Nitrogen Balance, Autonomy, Safety and Tolerance of Enteral Diets Made of With Nutrilon Without Lactose® Fortified by Concentration Versus by Maltodextrin and Oil Supplementation,After Surgery for Congenital Heart Disease, in Infants.
Status: TERMINATED
Conditions: Congenital Heart Disease in Children
Interventions: DIETARY_SUPPLEMENT: Nutrilon without lactose® fortified by concentration|DIETARY_SUPPLEMENT: Nutrilon without lactose® fortified by Maltodextrin and oil supplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Candesartan in Heart Failure Assessment of Reduction in Mortality and Morbidity (CHARM Alternative)
Status: COMPLETED
Conditions: Congestive Heart Failure
Interventions: DRUG: Candesartan|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Safety of Flublok® Versus Licensed IIV in Healthy, Medically Stable Adults ≥ 50 Years of Age
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Flublok|BIOLOGICAL: Afluria
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Improving Response to Immunotherapy in Patients With Advanced Hepatocellular Carcinoma and Chronic Hepatitis C Virus Infection With Direct-Acting Antiviral Therapy
Status: RECRUITING
Conditions: Liver Cancer
Interventions: DRUG: Bevacizumab|DRUG: Atezolizumab|DRUG: Sofosbuvir|DRUG: Velpatasvir|DRUG: Voxilaprevir|DRUG: Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tools to Improve Medication Continuity in Adolescents With ADHD
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: OTHER: Mehealth for ADHD software with medication continuity tools|OTHER: Mehealth for ADHD software without medication continuity tools
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: aiTBS for NSSI and Suicide in Adolescent Depression
Status: RECRUITING
Conditions: Non Suicidal Self Injury|Suicidal Ideation|Suicide and Self-harm
Interventions: DEVICE: Active iTBS|DEVICE: Sham iTBS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: OTC Naproxen and Acetaminophen Anti-Inflammatory Action in Dental Implant Patients
Status: COMPLETED
Conditions: Osseointegrated Dental Implantation|Pain, Acute
Interventions: DRUG: Naproxen|DRUG: Acetaminophen|DRUG: Tramadol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Phase II Study of Ibrutinib in Advanced Carcinoid and Pancreatic Neuroendocrine Tumors
Status: COMPLETED
Conditions: Carcinoid Tumors|Pancreatic NET
Interventions: DRUG: Ibrutinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Sodium Fluorescein Use During Intraoperative Cystoscopy After Total Laparoscopic Hysterectomy
Status: COMPLETED
Conditions: Ureteral Injury
Interventions: DRUG: sodium fluorescein injection 10%
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: RecoverPC: Relugolix vs GnRH Agonist in Quality of Life
Status: RECRUITING
Conditions: Prostate Cancer|Prostatic Neoplasms
Interventions: DRUG: Relugolix|DRUG: Leuprolide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Preemptive HLA Genotyping for the Safe Use of Infliximab-combination Therapy in Inflammatory Bowel Disease
Status: UNKNOWN
Conditions: Inflammatory Bowel Diseases|Ulcerative Colitis|Crohn Disease
Interventions: GENETIC: HLADQA1*05A>G screening|OTHER: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: CHemotherapy And Stool Transplant in PDAC (CHASe-PDAC)
Status: NOT_YET_RECRUITING
Conditions: Unresectable or Metastatic Advanced Pancreatic Ductal Adenocarcinoma
Interventions: DRUG: Fecal Microbiota Transplantation|DRUG: PEG3350|DRUG: Gemcitabine|DRUG: nab-Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Lumasiran in Patients With Advanced Primary Hyperoxaluria Type 1
Status: ACTIVE_NOT_RECRUITING
Conditions: Primary Hyperoxaluria Type 1|Primary Hyperoxaluria
Interventions: DRUG: Lumasiran
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Personalized Transcranial Direct Current Stimulation in Stroke Recovery
Status: NOT_YET_RECRUITING
Conditions: Stroke
Interventions: DEVICE: Transcranial direct current stimulation (tDCS) with OT|DEVICE: Sham tDCS with OT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: 221AD301 Phase 3 Study of Aducanumab (BIIB037) in Early Alzheimer's Disease
Status: TERMINATED
Conditions: Alzheimer's Disease
Interventions: DRUG: Aducanumab (BIIB037)|DRUG: Aducanumab (BIIB037)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Early Screening of Emotional, Behavioral and Autism Spectrum Disorders in Children With Functional Constipation.
Status: UNKNOWN
Conditions: Functional Constipation|Emotional Problems|Behavioural Problems|Developmental Disorder|Autism Spectrum Disorder
Interventions: OTHER: Screening Questionnaires
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Filgotinib in Long-Term Extension Study of Adults With Crohn's Disease
Status: TERMINATED
Conditions: Crohn's Disease
Interventions: DRUG: Filgotinib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Superiority of Newly Developed Over Basic Echinacea Formulations for the Treatment of Respiratory Tract Infections
Status: COMPLETED
Conditions: Respiratory Tract Infections
Interventions: DRUG: Echinacea purpurea alcoholic extract
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study to Evaluate the Interest of PDL in the Management of Telangiectasia of the Face and Neckline in Systemic Scleroderma
Status: COMPLETED
Conditions: Telangiectasia
Interventions: DEVICE: pulsed dye laser
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lipid Efficacy and Safety in Participants With Mixed Hyperlipidemia (MK-0524B-024)
Status: COMPLETED
Conditions: Mixed Hyperlipidemia
Interventions: DRUG: MK-0524A|DRUG: Atorvastatin|DRUG: Simvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT