pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Nutrition Intervention During Chemotherapy
Status: UNKNOWN
Conditions: Cancer Patients Receiving Chemotherapy or Chemoradiotherapy
Interventions: DIETARY_SUPPLEMENT: Daily intake for 10 weeks (+/- 2 weeks)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of Daratumumab in Patients With Newly Diagnosed Multiple Myeloma
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: daratumumab|DRUG: carfilzomib|DRUG: lenalidomide|DRUG: dexamethasone|DRUG: dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Wheelchair In-Seat Activity Tracker
Status: COMPLETED
Conditions: Pressure Ulcer, Buttock|Pressure Injury|Pressure Ulcer
Interventions: OTHER: WiSAT System, Passive Feedback|OTHER: WiSAT System, Active Feedback
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Phase III Xevinapant (Debio 1143) and Radiotherapy in Resected LA SCCHN, High Risk, Cisplatin-ineligible Participants (XRAY VISION)
Status: ACTIVE_NOT_RECRUITING
Conditions: Head and Neck Cancer
Interventions: DRUG: Xevinapant (Debio 1143)|RADIATION: IMRT|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of BMS-986205 Alone and in Combination With Nivolumab in Chinese Patients With Advanced Malignant Solid Tumors
Status: COMPLETED
Conditions: Advanced Cancer
Interventions: DRUG: BMS-986205|BIOLOGICAL: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Systolic Hypertension in Europe Placebo-Controlled Trial
Status: TERMINATED
Conditions: Isolated Systolic Hypertension
Interventions: DRUG: Active treatment with nitrendipine (10-40 mg/day).
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Chest Tube After a Video-assisted Thoracoscopic Surgery Pulmonary Wedge Resection
Status: UNKNOWN
Conditions: Lung Diseases, Interstitial|Pulmonary Nodule, Solitary
Interventions: PROCEDURE: Do not leave a chest tube in the pleural cavity.|PROCEDURE: Do leave a chest tube in the pleural cavity.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of CI-135 CAR-T Cells in Subjects With Relapsed or Refractory Acute Myeloid Leukemia
Status: RECRUITING
Conditions: Acute Myeloid Leukemia
Interventions: BIOLOGICAL: CI-135 CAR-T cells (0.5 x 10^6 CAR-T+ cells/kg，1.0 x 10^6 CAR-T+ cells/kg)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bortezomib and Docetaxel in Treating Patients With Recurrent or Metastatic Head and Neck Cancer
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: DRUG: bortezomib|DRUG: docetaxel|OTHER: laboratory biomarker analysis|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Donor Bone Marrow Transplant With or Without G-CSF in Treating Young Patients With Hematologic Cancer or Other Diseases
Status: COMPLETED
Conditions: Childhood Acute Lymphoblastic Leukemia in Remission|Childhood Acute Myeloid Leukemia in Remission|Childhood Chronic Myelogenous Leukemia|Childhood Myelodysplastic Syndromes|Chronic Phase Chronic Myelogenous Leukemia|de Novo Myelodysplastic Syndromes|Juvenile Myelomonocytic Leukemia|Previously Treated Myelodysplastic Syndromes|Recurrent Childhood Acute Lymphoblastic Leukemia|Secondary Myelodysplastic Syndromes
Interventions: PROCEDURE: allogeneic bone marrow transplantation|OTHER: laboratory biomarker analysis|BIOLOGICAL: filgrastim
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immune Checkpoint Inhibitor Nivolumab in People With Recurrent Select Rare CNS Cancers
Status: RECRUITING
Conditions: Medulloblastoma|Ependymoma|Pineal Region Tumors|Choroid Plexus Tumors|Atypical/Malignant Meningioma
Interventions: DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Tipifarnib in Patients With Previously-Treated, Advanced, HRAS Mutant Urothelial Carcinoma
Status: UNKNOWN
Conditions: Urothelial Carcinoma
Interventions: DRUG: tipifarnib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Effectiveness of CAM Therapies in Pediatric Patients Undergoing Sedation
Status: COMPLETED
Conditions: Neurological Disorders
Interventions: OTHER: Active Music Therapy|OTHER: Passive Music Therapy|OTHER: Distraction Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pulmonary Inflammation in COVID-19 ARDS
Status: UNKNOWN
Conditions: ARDS Due to Disease Caused by Severe Acute Respiratory Syndrome Coronavirus 2|COVID-19 Acute Respiratory Distress Syndrome
Interventions: DIAGNOSTIC_TEST: Bronchoalveolar lavage
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: 10cmH2O Peep Application and Cerebral Oxygenation in Laparoscopic Surgery: a Comparative Study With Invos and Foresight Devices
Status: COMPLETED
Conditions: Laparoscopic Cholecystectomy
Interventions: DEVICE: FORESİGHT cerebral oxygen monitor and INVOS cerebral oxygen monitor|DEVICE: FORESIGHT and INVOS monitor
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Trial of Overminus Spectacle Therapy for Intermittent Exotropia
Status: COMPLETED
Conditions: Intermittent Exotropia
Interventions: DEVICE: Overminus treatment|DEVICE: Non-overminus treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prevention Management Model for Early Childhood Caries (MAYA Project)
Status: COMPLETED
Conditions: Dental Caries
Interventions: DRUG: Chlorhexidine gluconate|DEVICE: Fluoride Varnish
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: NeuMoDx PrEDiCTiNG Study Evaluation Plan
Status: COMPLETED
Conditions: Chlamydia Trachomatis Infection|Neisseria Gonorrheae Infection
Interventions: DIAGNOSTIC_TEST: NeuMoDx CT/NG Assay|DIAGNOSTIC_TEST: FDA-cleared NAATs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: mDCF + Avelumab in Resectable Esophago-gastric Adenocarcinoma (EGA)
Status: UNKNOWN
Conditions: Gastric Adenocarcinoma|Esophageal Adenocarcinoma
Interventions: DRUG: mDCF + Avelumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cytokine Filtration in Lung Transplantation: A Swedish National Study (GLUSorb)
Status: RECRUITING
Conditions: Lung Transplant Failure|Lung Transplant; Complications
Interventions: DEVICE: Device: CytoSorb
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Registry of Patients for MRI With Non-MRI Conditional Pacemakers and ICD Non-MRI Conditional Pacemakers and ICD
Status: COMPLETED
Conditions: MRI Scans|Magnetic Resonance Imaging|Pacemaker|Implantable Cardioverter Defibrillator
Interventions: OTHER: MRI Scan
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Randomized Controlled Trial: A Digital Intervention to Prevent the Initiation of Opioid Misuse in Adolescents in School-based Health Centers
Status: ACTIVE_NOT_RECRUITING
Conditions: Opioid Misuse
Interventions: BEHAVIORAL: PlaySmart|OTHER: Video Game Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: PI3K Inhibitor BYL719 in Combination With the HSP90 Inhibitor AUY922 in Patients With Advanced or Metastatic Gastric Cancer
Status: COMPLETED
Conditions: Stomach Neoplasms Esophageal Neoplasms Metastatic Gastric Cancer Mutated PI3KCA Protein Overexpressed HER2 Protein
Interventions: DRUG: AUY922|DRUG: BYL719
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating Navitoclax After Failure of Standard Treatments of Azacitidine or Decitabine and Venetoclax in Patients With Aggressive Myelodysplastic Syndrome
Status: RECRUITING
Conditions: Myelodysplastic Syndrome|Recurrent Myelodysplastic Syndrome|Refractory Myelodysplastic Syndrome
Interventions: BIOLOGICAL: Navitoclax|DRUG: Venetoclax|DRUG: Decitabine|PROCEDURE: Bone Marrow Biopsy|PROCEDURE: Biospecimen Collection|OTHER: Laboratory Biomarker Analysis|OTHER: Quality-of-Life Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HR070803 in Combination With Oxaliplatin, 5-FU/LV Versus AG for First-line Treatment of Advanced Pancreatic Cancer
Status: RECRUITING
Conditions: First-line Treatment of Advanced Pancreatic Cancer
Interventions: DRUG: HR070803; Oxaliplatin; 5Fluorouracil; Calcium folinate|DRUG: nab-paclitaxel; gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Patient and Staff Safety During Aorto-iliac Revascularization Procedures Under Automated Fusion Imaging Guidance With Controls
Status: TERMINATED
Conditions: Patient and Staff Radiation Exposure During Aorto-iliac Endovascular Revascularization
Interventions: DEVICE: Control with imaging guidance|DEVICE: Control without imaging guidance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Resistant Starch, Epigallocatechin Gallate and Chlorogenic Acid for Body Weight Loss in Menopause
Status: UNKNOWN
Conditions: Overweight
Interventions: OTHER: Nutritional counseling|DIETARY_SUPPLEMENT: Equikilon-3 months|DIETARY_SUPPLEMENT: Equikilon-6 months
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating Cancer Survivorship Care Models
Status: COMPLETED
Conditions: Quality of Life|Cancer
Interventions: OTHER: Organizational Interview|OTHER: Organizational Survey|OTHER: Survivor Survey (1): Pre-Visit Baseline|OTHER: Survivor Survey (2): Post-Visit|OTHER: Survivor Survey (3): 3 Month Post-Visit|OTHER: Survivor Survey (4): 6 Month Post-Visit|OTHER: Clinician Survey
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: PDE-4 Inhibitor Roflumilast and GLP-1 Agonist Liraglutide in Polycystic Ovary Syndrome
Status: COMPLETED
Conditions: PCOS|Obesity
Interventions: DRUG: metformin|DRUG: liraglutide|DRUG: roflumilast
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Pemetrexed and Bevacizumab for Participants With Advanced Non-Small Cell Cancer
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: Pemetrexed|DRUG: Cisplatin|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rosiglitazone for Clozapine Induced Glucose Metabolism Impairment
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: rosiglitazone|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Promoting Benzodiazepine Cessation Through an Electronically-delivered Patient Self-management Intervention
Status: ACTIVE_NOT_RECRUITING
Conditions: Taking Benzodiazepines for Any Reason for 3 Months|Benzodiazepine Dependence
Interventions: BEHAVIORAL: EMPOWER-ED
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Finding the Best Tamoxifen Dose for Breast Cancer Risk Reduction in Premenopausal Women, RENAISSANCE Trial
Status: NOT_YET_RECRUITING
Conditions: Breast Carcinoma|Breast Ductal Carcinoma In Situ|Breast Lobular Carcinoma In Situ|Estrogen Receptor-Positive Breast Carcinoma
Interventions: PROCEDURE: Biopsy|PROCEDURE: Biospecimen Collection|PROCEDURE: Mammography|OTHER: Questionnaire Administration|DRUG: Tamoxifen
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Sirolimus In Liver Transplantation for Hepatocellular Carcinoma (HCC)
Status: COMPLETED
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Sirolimus|DRUG: m-TOR inhibitor free
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cetuximab Compared to Mitomycin-C and 5-Fluorouracil for Locally Advanced Squamous Cell Carcinomas of the Head and Neck
Status: TERMINATED
Conditions: Head and Neck Neoplasms
Interventions: DRUG: Cetuximab|DRUG: Mitomycin-C/ 5-Fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of 2 Doses of a Hepatitis B Vaccine (V232 RECOMBIVAX HB) in Healthy Infants (V232-057)
Status: COMPLETED
Conditions: Hepatitis B
Interventions: BIOLOGICAL: Modified Process Hepatitis B Vaccine (Experimental)|BIOLOGICAL: Hepatitis B Vaccine (Recombinant)|BIOLOGICAL: Hepatitis B Vaccine (Recombinant)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Mibefradil Dihydrochloride and Temozolomide in Treating Patients With Recurrent Glioma
Status: COMPLETED
Conditions: Brain and Central Nervous System Tumors
Interventions: DRUG: temozolomide|OTHER: 3'-deoxy-3'-[18F]fluorothymidine|OTHER: pharmacological study|DRUG: Mibefradil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Thales Thermography Triage (3T) - Pilot Project
Status: UNKNOWN
Conditions: Fever
Interventions: DEVICE: Thermography|DEVICE: Tympanic Thermometer|DEVICE: Forehead Thermometer|DEVICE: 62 Max + Infra-red thermometer
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evidence-Based Osteopathy for Tension-Type Headache (EBOTTH)
Status: WITHDRAWN
Conditions: Tension-Type Headache
Interventions: OTHER: osteopathic manipulative treatment|OTHER: sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tipifarnib and Gemcitabine Hydrochloride in Treating Women With Metastatic Breast Cancer
Status: COMPLETED
Conditions: Recurrent Breast Carcinoma|Stage IV Breast Cancer
Interventions: DRUG: Gemcitabine Hydrochloride|DRUG: Tipifarnib|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stereotactic Radiotherapy for Renal Cancers
Status: COMPLETED
Conditions: Renal Cancer
Interventions: RADIATION: Stereotactic radiotherapy 4 x 8 Gy|RADIATION: Stereotactic radiotherapy 5 x 8 Gy|RADIATION: Stereotactic radiotherapy 4 x 10 Gy|RADIATION: Stereotactic radiotherapy 4 x 12 Gy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anti-tumour Activity of (177Lu) rhPSMA-10.1 Injection
Status: RECRUITING
Conditions: Prostate Cancer|Metastatic Castration-resistant Prostate Cancer|mCRPC|Urogenital Neoplasms|Prostatic Neoplasms|Prostatic Diseases
Interventions: DRUG: 177Lu-rhPSMA-10.1 injection|DIAGNOSTIC_TEST: 18F-rhPSMA-7.3 injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Activity Study of Sunitinib In Metastatic Pretreated Urothelial Cancer
Status: UNKNOWN
Conditions: Urinary Bladder Neoplasms
Interventions: DRUG: SUNITINIB
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Cycloset on Glycemic Control When Added to Glucagon-like Peptide 1 (GLP-1) Analogue Therapy
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: Cycloset
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Study of Letrozole Alone or Letrozole With Zoledronic Acid in Early Breast Cancer, Neoadjuvant Therapy
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Zoledronic Acid; Letrozole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized Trial of Medical and Surgical Treatments for Patients With GERD Symptoms That Are Refractory to Proton Pump Inhibitors
Status: COMPLETED
Conditions: GERD
Interventions: DEVICE: Nissen fundoplication|DRUG: baclofen|DRUG: Desipramine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Valsartan and Amlodipine Compared to Losartan and Amlodipine in Hypertensive Patients
Status: UNKNOWN
Conditions: Essential Hypertension
Interventions: DRUG: valsartan/amlodpine|DRUG: losartan/amlodpine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Predictive Value of the Immune Response of the Host in Clostridium Difficile Infections
Status: COMPLETED
Conditions: Clostridium Difficile Infection
Interventions: BIOLOGICAL: Serum|BIOLOGICAL: Stools|BIOLOGICAL: Saliva|BIOLOGICAL: Whole blood
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety and Performance Evaluation of a New Catheter Range for Lead Implantation at Interventricular Septum
Status: NOT_YET_RECRUITING
Conditions: Bradycardia|Cardiac Resynchronization Therapy|Left Bundle Branch Area Pacing
Interventions: DEVICE: Use of FLEXIGO delivery catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Decline in Walking Performance in Adults With Cerebral Palsy - Influence of Performance Fatigability
Status: RECRUITING
Conditions: Muscle Spasticity|Paralysis; Cerebral
Interventions: OTHER: Fatigability assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: An Open, Non-comparative, Multicenter Investigation to Evaluate the Safety and Performance of Exufiber Ag+, a Gelling Fiber Silver Dressing, When Used in Medium to High Exuding Chronic Wounds
Status: TERMINATED
Conditions: Pressure Ulcer|Diabetic Foot Ulcer|Venous Leg Ulcer
Interventions: DEVICE: ExufiberAG+
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Active Isolated Stretching Versus Myofascial Release of Knee Joint in Office Workers
Status: ACTIVE_NOT_RECRUITING
Conditions: Stiffness; Spine|Mobility Limitation
Interventions: DIAGNOSTIC_TEST: Active isolated stretching (AIS)|DIAGNOSTIC_TEST: Myofascial release (MFR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Clonidine to Treat Iatrogenic-induced Opioid Dependence in Infants
Status: TERMINATED
Conditions: Neonatal Abstinence Syndrome
Interventions: DRUG: Clonidine HCL|DRUG: saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Heliox and Posture in Patients With Asthma
Status: COMPLETED
Conditions: Acute Asthma
Interventions: OTHER: HELIOX|OTHER: OXYGEN|OTHER: HELIOX+POSTURE|OTHER: OXYGEN + POSTURE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Hydrochlorothiazide in the Treatment of Hypernatremia in Critically Ill Patients
Status: UNKNOWN
Conditions: Hypernatremia|Critical Illness
Interventions: DRUG: Hydrochlorothiazide 50Mg|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of a Psychosocial Intervention for Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Neoplasms
Interventions: BEHAVIORAL: Psycho-behavioural intervention arm (PBI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Corticosteroid Injection Verses High Energy Extracorporeal Shock Wave Therapy for Lateral Epicondylitis
Status: UNKNOWN
Conditions: Lateral Epicondylitis|Tennis Elbow
Interventions: PROCEDURE: extracorporeal shock wave therapy|DRUG: Kenalog (triamcinolone)|DRUG: lidocaine 1% (lidocaine HCl 20mg)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of [68Ga]FAPI-46 PET in Patients With Pancreatic Ductal Carcinoma
Status: RECRUITING
Conditions: PDAC - Pancreatic Ductal Adenocarcinoma|FAP
Interventions: DRUG: [68Ga]FAPI-46
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Mapracorat Ophthalmic Suspension, 3% for the Treatment of Ocular Inflammation and Pain Following Cataract Surgery
Status: COMPLETED
Conditions: Cataract|Inflammation|Surgery
Interventions: DRUG: Mapracorat|DRUG: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Olorinab in Irritable Bowel Syndrome With Predominant Constipation (IBS-C) and Irritable Bowel Syndrome With Predominant Diarrhea (IBS-D)
Status: TERMINATED
Conditions: Irritable Bowel Syndrome
Interventions: DRUG: Olorinab|DRUG: Olorinab|DRUG: Olorinab|DRUG: Placebo|DRUG: Olorinab|DRUG: Olorinab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics of Sugammadex for the Reversal of Moderate Neuromuscular Blockade in Patients During Renal Transplantation
Status: UNKNOWN
Conditions: Pharmacokinetics
Interventions: DRUG: Sugammadex
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Efficacy, Safety, and Tolerability of BOS-589 in the Treatment of Patients With Diarrhea-predominant Irritable Bowel Syndrome (IBS-D)
Status: COMPLETED
Conditions: Diarrhea-predominant Irritable Bowel Syndrome
Interventions: DRUG: BOS-589|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Supplementation With HMB and Glutamine in Wound Healing on Bloody Areas
Status: UNKNOWN
Conditions: Wound Healing|Diabetic
Interventions: DRUG: glutamine supplementation|DRUG: HMB|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Tiotropium Bromide Combined With Odaterol on Small Airway Remodeling in Patients With Mild to Moderate Chronic Obstructive Pulmonary Disease
Status: RECRUITING
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Tiotropium Bromide Combined With Odaterol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Reduced Intensity Donor Stem Cell Transplant in Treating Patients With High Risk Acute Lymphocytic Leukemia in Complete Remission
Status: COMPLETED
Conditions: Adult Acute Lymphoblastic Leukemia in Remission|Childhood Acute Lymphoblastic Leukemia in Remission|Recurrent Adult Acute Lymphoblastic Leukemia|Recurrent Childhood Acute Lymphoblastic Leukemia
Interventions: PROCEDURE: nonmyeloablative allogeneic hematopoietic stem cell transplantation|BIOLOGICAL: donor lymphocytes|DRUG: cyclosporine|RADIATION: total-body irradiation|DRUG: fludarabine phosphate|DRUG: mycophenolate mofetil|OTHER: laboratory biomarker analysis|PROCEDURE: peripheral blood stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study: 3 mg Estradiol Valerate (EV) With and Without Levomefolate Calcium
Status: COMPLETED
Conditions: Contraception|Ovulation Inhibition
Interventions: DRUG: Estradiol Valerate (EV) / Levomefolate Calcium (BAY98-7078)|DRUG: Estradiol Valerate (EV) (BAY86-4980)|DRUG: Levomefolate Calcium (BAY86-7660)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioheart Rapamycin Drug-Eluting Bioresorbable Coronary Stent System Clinical Study
Status: UNKNOWN
Conditions: Coronary Artery Disease|Antineoplastic Agents
Interventions: DEVICE: study group|DEVICE: control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Effectiveness of BOTOX (Botulinum Toxin Type A) Injections for the Change of Masseter Muscle Prominence in Adult Participants
Status: RECRUITING
Conditions: Masseter Muscle Prominence
Interventions: DRUG: BOTOX|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Stereotactic Radiosurgery in Treating Patients With Brain Metastases
Status: TERMINATED
Conditions: Metastatic Cancer|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: PROCEDURE: therapeutic conventional surgery|RADIATION: stereotactic radiosurgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Exergame Program Structured Via Analytic Hierarchy Process on Trunk Control and Upper Extremity Functionality
Status: COMPLETED
Conditions: Cerebral Palsy
Interventions: OTHER: Video-game based exercise - Exergame|OTHER: Activity Based Exercise Group (AG)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Rifaximin for the Treatment of Persistent Symptoms in Patients With Celiac Disease
Status: COMPLETED
Conditions: Celiac Disease
Interventions: DRUG: Rifaximin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Thalidomide to Patients With Previously Untreated Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: thalidomide|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Natrecor (Nesiritide) in Transplant-Eligible Management of Congestive Heart Failure-TMAC
Status: TERMINATED
Conditions: Congestive Heart Failure|Cardiac Transplantation|Renal Insufficiency|Renal Failure
Interventions: DRUG: Natrecor (nesiritide)+Standard Care+dobutamine or milrinone|DRUG: Placebo+Standard Care+dobutamine or milrinone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Anti-obesity Effect of Koji-extracted Beverage Fermented With Pediococcus Pentosaceus LP28
Status: COMPLETED
Conditions: Overweight
Interventions: DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: Koji-extracted beverage fermented with Pediococcus pentosaceus LP28
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Selinexor Combined With Chidamide in Relapsed/Refractory Acute Leukemia (AML) Patients
Status: RECRUITING
Conditions: Acute Myeloid Leukemia (Relapsed/Refractory)
Interventions: DRUG: Selinexor|DRUG: Chidamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Danish Non-vitamin K Antagonist Oral Anticoagulation Study in Patients With Venous Thromboembolism (DANNOAC-VTE)
Status: RECRUITING
Conditions: Deep Vein Thrombosis|Pulmonary Embolism
Interventions: DRUG: Dabigatran Etexilate Oral Capsule|DRUG: Rivaroxaban Oral Tablet|DRUG: Edoxaban Oral Tablet|DRUG: Apixaban Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Of The Repeat Dosing Of Ketoconazole On The Pharmacokinetics Of A Single Dose Of Pazopanib (GW786034) Eye Drops
Status: COMPLETED
Conditions: Macular Degeneration
Interventions: DRUG: pazopanib eye drops|DRUG: Ketoconozole tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Safety and Tolerability of SCR-6920 Capsule in Patients With Advanced Malignant Tumors
Status: RECRUITING
Conditions: Solid Tumor|Non Hodgkin Lymphoma
Interventions: DRUG: SCR-6920 capsule|DRUG: SCR-6920 capsule|DRUG: SCR-6920 capsule|DRUG: SCR-6920 capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility of Cetuximab Associated With Concomitant Radio-Chemotherapy in Patients With Locally Advanced Non Small Cell Lung Cancer
Status: COMPLETED
Conditions: Non-Small-Cell Lung Carcinoma
Interventions: DRUG: cisplatin, vinorlebine, cetuximab|DRUG: cisplatine, etoposide, cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: rTMS for Working Memory Deficits in Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder
Interventions: DEVICE: Repetitive Transcranial Magnetic Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Platelet-rich Fibrin and Vitamin Dꝫ Injections on Canine Retraction
Status: RECRUITING
Conditions: Acceleration of Tooth Movement
Interventions: OTHER: Platelet-rich fibrin|OTHER: Vitamin D3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase IB Study of Gemcitabine, Docetaxel and Bevacizumab in Patients With Soft Tissue Sarcoma
Status: COMPLETED
Conditions: Sarcoma
Interventions: DRUG: Gemcitabine, Docetaxel and Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dissecting the Role of Distal Embolization of Athero-thrombotic Material in Primary PCI: the ThrombOticBurden and mIcrovAscularobStruction (TOBIAS) Study.
Status: UNKNOWN
Conditions: Acute Myocardial Infarction
Interventions: DEVICE: angio-guided thrombus aspiration (Eliminate catheter, Terumo, Tokyo, Japan)|DEVICE: OCT-guided thrombus aspiration (Eliminate catheter, Terumo, Tokyo, Japan)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective Randomized Trial of Stratafix vs. Vicryl in Total Hip Arthroplasty.
Status: COMPLETED
Conditions: Wound; Hip
Interventions: DEVICE: STRATIFIX|DEVICE: VICRYL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: REMAP-WEST-FLARE - FLAg for Review Efficacy Investigation
Status: NOT_YET_RECRUITING
Conditions: COPD
Interventions: DEVICE: Senti Wear device system with Senti-AI subsystem
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Comparative Study of an Innovative 3-lead Wireless Water Resistant Holter System and a Conventional Holter System
Status: COMPLETED
Conditions: Cardiac Arrhythmia
Interventions: DEVICE: An innovative 3-lead wireless water resistant Holter device|DEVICE: A conventional device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Clinical Trial to Evaluate a Recombinant Hepatitis E Vaccine in Healthy Adults
Status: COMPLETED
Conditions: Hepatitis E
Interventions: BIOLOGICAL: 30μg/0.5ml Hepatitis E vaccine|BIOLOGICAL: 30μg/0.5ml Recombinant Hepatitis E vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: ERAS Protocol in Pancreaticoduodenectomy and Total Pancreatectomy
Status: TERMINATED
Conditions: Pancreatic Cancer|Surgery--Complications|Pancreatic Fistula|Delayed Gastric Emptying|Pancreatic Hemorrhage
Interventions: PROCEDURE: ERAS protocol preoperative actions|PROCEDURE: ERAS protocol intraoperative actions|PROCEDURE: ERAS protocol postoperative actions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Efficacy and Safety of GSK239512 in Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: GSK239512|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: BRown Fat Activity Measurement With Infrared imaginG tHermography andThermogenesis - the BRIGHT Study
Status: COMPLETED
Conditions: Energy Expenditure|Obesity|Adipose Tissue, Brown
Interventions: OTHER: Cold air|OTHER: Cold water
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Low-Intensity Preparation and Allogeneic Transplant in Patients With Cancers of the Blood
Status: COMPLETED
Conditions: Myeloma, Plasma-Cell|Lymphoma, Malignant|Myeloproliferative Disorders|Myelodysplastic Syndromes|Waldenstrom's Macroglobulinemia
Interventions: PROCEDURE: Reduced intensity conditioning with allogeneic transplant
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating Safety & Efficacy of Apremilast in the Treatment of Cutaneous Disease in Patients With Recalcitrant Dermatomyositis
Status: COMPLETED
Conditions: Dermatomyositis, Adult Type
Interventions: DRUG: Apremilast 30mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Therapy in Amyotrophic Lateral Sclerosis (ALS)
Status: COMPLETED
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DRUG: Pioglitazone and Tretinoin|DRUG: Tretinoin and Pioglitazone HCL|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Treatment on Activity and Muscle Function in Pediatric Patients With Scoliosis
Status: ENROLLING_BY_INVITATION
Conditions: Scoliosis
Interventions: PROCEDURE: Spinal Fusion Surgery|OTHER: Bracing|DEVICE: Tri-axial Accelerometers|OTHER: Shear Wave Elastography (SWUE)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Venous Thromboembolism in Renally Impaired Patients and Direct Oral Anticoagulants
Status: TERMINATED
Conditions: Renal Insufficiency
Interventions: DRUG: Apixaban|DRUG: Rivaroxaban|DRUG: Heparin|DRUG: VKA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study in Rheumatoid Arthritis for Subjects Who Completed Preceding Study M13-390 With Adalimumab
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: BIOLOGICAL: New formulation adalimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of VVD-101 for the Treatment of Delayed Alcohol-Induced Headaches
Status: COMPLETED
Conditions: Delayed Alcohol Induced Headache
Interventions: DRUG: VVD-101|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Non-Interventional Study of NovoSeven® Used in Patients With Haemophilia A and B With Inhibitors Under Normal Clinical Practice
Status: COMPLETED
Conditions: Congenital Bleeding Disorder|Haemophilia A With Inhibitors|Haemophilia B With Inhibitors
Interventions: DRUG: eptacog alfa (activated)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Randomized Phase 2 Study to Investigate Efficacy of ALECSAT in Patients With GBM Measured Compared to Avastin/Irinotecan
Status: TERMINATED
Conditions: Glioblastoma Multiforme
Interventions: BIOLOGICAL: ALECSAT|DRUG: Bevacizumab/Irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SH-SS and GSH-GSSG Homeostasis in Post-stroke Patients
Status: COMPLETED
Conditions: Stroke
Interventions: OTHER: Standard neurorehabilitation|DIAGNOSTIC_TEST: Thiol-Disulphide Homeostasis|DIAGNOSTIC_TEST: Oxidized-reduced Glutathione Homeostasis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: MiniMUD Study - Unrelated Reduced Intensity Conditioning With Treosulfan® for Allogeneic Stem Cell Transplantation in Patients With Hematological Malignancies
Status: UNKNOWN
Conditions: Hematological Malignancies|Allogeneic Transplantation
Interventions: DRUG: treosulfan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: First-in- Human Imaging of Multiple Myeloma Using 89Zr-DFO-daratumumab, a CD38-targeting Monoclonal Antibody
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: 89Zr-daratumumab|DEVICE: PET/CT scans|OTHER: Blood draws
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Temozolomide and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme or Anaplastic Astrocytoma
Status: COMPLETED
Conditions: Glioblastoma Multiforme/Anaplastic Astrocytoma
Interventions: DRUG: temozolomide|RADIATION: Hypofractionated radiation therapy|RADIATION: Intensity-modulated radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Meloxicam Tablets on Bleeding Time in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Meloxicam - low|DRUG: Meloxicam - medium|DRUG: Meloxicam - high|DRUG: Placebo|DRUG: Extended-release indomethacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Retinal and Choroidal Microvascular Changes During Pregnancy Period Detected With Optical Coherence Tomography Angiography
Status: TERMINATED
Conditions: Pregnancy Related
Interventions: DIAGNOSTIC_TEST: Optical Coherence Tomography,Optical Coherence Tomography Angiography(Topcon)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Endoscopic Balloon Dilation vs Surgery to Treat Short Strictures in Fibrostenosing Crohns Disease: An RCT
Status: UNKNOWN
Conditions: Crohn Disease
Interventions: PROCEDURE: Surgery|PROCEDURE: TTS balloon dilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I Trial of BCMA-TGF-BETA CAR-T Cells in Relapsed, Refractory Myeloma
Status: NOT_YET_RECRUITING
Conditions: Multiple Myeloma
Interventions: BIOLOGICAL: BCMA-TGFβ CAR-T cells (0.50 x 10^6 cells/kg)|BIOLOGICAL: BCMA-TGFβ CAR-T cells (0.75 x10^6 cells/kg)|BIOLOGICAL: BCMA-TGFβ CAR-T cells (1 x 10^6 cells/kg)|BIOLOGICAL: BCMA-TGFβ CAR-T cells (2.5 x 10^6 cells/kg)|BIOLOGICAL: Maximum tolerated dose
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Sc-FOS for Pouchitis Prevention
Status: COMPLETED
Conditions: Pouchitis
Interventions: DRUG: Short-Chain Fructooligosaccharide|DRUG: Maltodextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Stereotactic Ablative Radiotherapy(SBRT) Followed by Atezolizumab / Tiragolumab in Treatment-naive Patients With Metastatic Non-small Cell Lung Cancer
Status: UNKNOWN
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: atezolizumab / tiragolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Parenting Matters: Helping Parents With Young Children
Status: COMPLETED
Conditions: Sleep Problems|Behavior Problems|Child Behavior
Interventions: BEHAVIORAL: Self-help treatment booklet and telephone support|BEHAVIORAL: Usual care by a family physician
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fitness Assessment in Young Adults Recovered From Lymphoma
Status: COMPLETED
Conditions: Young Adults|Lymphoma, Non-Hodgkin|Hodgkin Disease
Interventions: OTHER: Indirect calorimetric test during submaximal exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparison of Topical Treatment for Inflammatory Secretions of the Conjonctiva (Patients With Ocular Prostheses)
Status: RECRUITING
Conditions: Ocular Inflammation|Ocular Prostheses
Interventions: DRUG: Hydrocortisone|DRUG: Dexamethasone|OTHER: Povidone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: NOYA CoCr Biodegradable Coating Sirolimus-Eluting Coronary Stent System
Status: UNKNOWN
Conditions: Coronary Artery Diseases
Interventions: DEVICE: stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: General Anesthesia and Paravertebral Blocks vs. General Anesthesia Only: Influence Inflammation Factors and Clinical Outcomes in Modified Radical Mastectomy
Status: COMPLETED
Conditions: Anesthesia, Local|Anesthesia|Inflammatory Response|Pain, Postoperative
Interventions: PROCEDURE: Paravertebral block|PROCEDURE: General Anesthesia
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of a Novel Intervention Aimed at Instilling Future-oriented Mindsets and Behaviors Using a Smartphone Application and Immersive Virtual Reality
Status: COMPLETED
Conditions: Future Orientation|Self-defeating Behavior|Future Self-identification
Interventions: BEHAVIORAL: FutureU|BEHAVIORAL: Goal-setting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Using an Online Patient Monitoring System to Improve Care for Children With Chronic Conditions
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder|Asthma|Autism Spectrum Disorder|Depression|Epilepsy
Interventions: OTHER: TriVox for clinical care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Morphologic Changes After Membrane Peeling With Air Tamponade and Balanced Salt Solution
Status: COMPLETED
Conditions: Epiretinal Membrane|Macular Pucker
Interventions: PROCEDURE: Air tamponade|PROCEDURE: Balanced salt solution filling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT