pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Efficacy and Safety of Rizatriptan-Naproxen (10/550 mg) in the Acute Treatment of Migraine
Status: RECRUITING
Conditions: Migraine
Interventions: DRUG: Rizatriptan 10 mg + Naproxen 550mg|DRUG: Maxalt 10Mg Tablet|DRUG: Flanax 550mg|DRUG: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Valsartan on Carotid Artery Disease
Status: COMPLETED
Conditions: Carotid Artery Diseases|Atherosclerosis
Interventions: DRUG: Valsartan|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prognosis and Long Term Pubertal Outcome of Girls Previously Diagnosed With a Prenatal Ovarian Cyst
Status: RECRUITING
Conditions: Ovarian Cyst
Interventions: OTHER: Hormonal analysis, pelvic US
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: SNIFF Multi-Device Study 2
Status: ACTIVE_NOT_RECRUITING
Conditions: Mild Cognitive Impairment|Cognitive Impairment
Interventions: DRUG: 20 IU Humulin® R U-100 (NDC: 0002-8215, Eli Lilly & Company)|DRUG: 40 IU Humulin® R U-100 (NDC: 0002-8215, Eli Lilly & Company)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Capecitabine/Erlotinib Followed of Gemcitabine Versus Gemcitabine/Erlotinib Followed of Capecitabine
Status: UNKNOWN
Conditions: Pancreatic Cancer
Interventions: DRUG: Gemcitabine|DRUG: Capecitabine|DRUG: Erlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diagnosis of Metastatic Tumors on 68Ga-FAPI PET-CT and Radioligand Therapy With 177Lu-EB-FAPI
Status: UNKNOWN
Conditions: 177Lu-EB-FAPI
Interventions: DRUG: 68Ga-FAPI for PET / CT scan and 177Lu-EB-FAPI for therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ciprofol Titrated Induction in Reducing Post-induction Hypotension in Geriatric Patients
Status: RECRUITING
Conditions: Post Induction Hypotension|Elderly
Interventions: DRUG: ciprofol|DRUG: propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Community-based Assessment of Skin Care, Allergies, and Eczema
Status: ACTIVE_NOT_RECRUITING
Conditions: Atopic Dermatitis|Atopic Disorders|Eczema|Atopic Eczema
Interventions: OTHER: Participant choice of over-the-counter emollients: Vaseline, Vanicream, CeraVe Healing Ointment, CeraVe cream, Cetaphil cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Influence of Enamel Matrix Derivative (Emdogain®) on Palate Wound Healing.
Status: UNKNOWN
Conditions: Palatal Wound
Interventions: PROCEDURE: Free gingival graft|DEVICE: Enamel Matrix Derivate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Gemcitabine, Oxaliplatin in Combination With Bevacizumab in Patients With Hepatocellular Carcinoma
Status: COMPLETED
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Gemcitabine|DRUG: Oxaliplatin|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Embolization of Pelvic Varicosities in Patients With Pelvic Congestion Syndrome
Status: TERMINATED
Conditions: Pelvic Pain|Varicose Veins
Interventions: PROCEDURE: Embolization of pelvic vein varicosities
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SIR-Spheres® for the Treatment of Unresectable Hepatocellular Carcinoma
Status: TERMINATED
Conditions: Carcinoma, Hepatocellular|Hepatoma
Interventions: DEVICE: SIR-Spheres microspheres
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Learn if a Combination of Fianlimab and Cemiplimab Versus Cemiplimab Alone is More Effective for Adult Participants With Advanced Non-Small Cell Lung Cancer (NSCLC)
Status: RECRUITING
Conditions: Advanced Non-Small Cell Lung Cancer
Interventions: DRUG: fianlimab|DRUG: cemiplimab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Single-dose Dexmedetomidine on Emergence Excitement in Adults With Nasotracheal Intubation After Orthognathic Surgery
Status: COMPLETED
Conditions: Agitation
Interventions: DRUG: saline|DRUG: Dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Clinical Pharmacist-led Appropriate Acid Suppression Therapy Stewardship Program
Status: COMPLETED
Conditions: Geriatric
Interventions: OTHER: Clinical Pharmacist-led Appropriate Acid Suppression Therapy Stewardship Program
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: ''Efficacy of Propranolol in the Treatment of Infantile Hemangioma"
Status: UNKNOWN
Conditions: Infantile Hemangioma
Interventions: DRUG: Propranolol Therapy for Infantile Hemangioma
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Study of NIR178 in Combination With PDR001 in Patients With Solid Tumors and Non-Hodgkin Lymphoma
Status: TERMINATED
Conditions: NSCLC, Non Small Cell Lung Cancer|RCC, Renal Cell Cancer|Pancreatic Cancer|Urothelial Cancer|Head and Neck Cancer|DLBCL, Diffused Large B Cell Lymphoma|MSS, Microsatellite Stable Colon Cancer|TNBC, Triple Negative Breast Cancer|Melanoma|mCRPC, Metastatic Castration Resistant Prostate Cancer
Interventions: DRUG: NIR178|DRUG: PDR001
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: AZD5672 Bioavailability Study in Healthy Male and Female Subjects
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: AZD5672|DRUG: AZD5672|DRUG: AZD5672|DRUG: AZD5672
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Effectiveness of Exercise and Patient-centred Education on Fibromyalgia
Status: UNKNOWN
Conditions: Fibromyalgia
Interventions: OTHER: Experimental: Exercise and Patient-centred education|OTHER: Active Comparator: Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy and Radiation Therapy With or Without Surgery in Treating Patients With Stage I Cancer of the Cervix
Status: TERMINATED
Conditions: Cervical Cancer
Interventions: DRUG: cisplatin|PROCEDURE: adjuvant therapy|PROCEDURE: conventional surgery|RADIATION: brachytherapy|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Pharmacokinetics of Velpatasvir in Participants With Normal Renal Function and Severe Renal Impairment
Status: COMPLETED
Conditions: Hepatitis C Virus
Interventions: DRUG: Velpatasvir
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Lactobacillus Acidophilus/Rhamnosus Combination for the Prevention of Antibiotic-associated Diarrhea in the Elderly
Status: TERMINATED
Conditions: Diarrhea|Clostridium Difficile
Interventions: OTHER: Lactobacillus acidophilus/rhamnosus|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Phase IV Clinical Trial to Study the Safety, Tolerability and Efficacy of Tinefcon in Patients With Plaque Psoriasis
Status: COMPLETED
Conditions: Plaque Psoriasis
Interventions: DRUG: TINEFCON
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combined Effects of Core Stability Exercises and Back Strengthening Exercises on Pregnancy-Induced Back Pain.
Status: NOT_YET_RECRUITING
Conditions: Low Back Pain
Interventions: OTHER: Core Stability Exercises|OTHER: Back Strengthening exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: TASO-001 in Combination With Recombinant Interleukin-2(Aldesleukin) in Advanced or Metastatic Solid Tumor
Status: COMPLETED
Conditions: Solid Tumor
Interventions: DRUG: TASO-001((TGF-β2 targeting anti-sense oligonucleotide)|COMBINATION_PRODUCT: Aldesleukin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Intraocular Pressure Following a Vitreoretinal Surgery Using Goldmann Applanation Tonometry, Icare and Accupen
Status: NOT_YET_RECRUITING
Conditions: Intraocular Pressure
Interventions: OTHER: Intraocular pressure measure
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Laryngeal Mask Airway (LMA) Protector for Minimally Invasive Thyroidectomy
Status: COMPLETED
Conditions: Sore Throat|Dysphagia|Postoperative Pain
Interventions: DEVICE: LMA Protector|DEVICE: Endotracheal tube
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Mometasone-furoate for Treatment of Eosinophilic Esophagitis - a Randomized Placebo Controlled Study.
Status: TERMINATED
Conditions: Eosinophilic Esophagitis
Interventions: DRUG: Mometasone furoate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility and Efficacy Study of the CardioPulmonary Management (CPM) System in Patients With Chronic Heart Failure (Beta Study)
Status: NOT_YET_RECRUITING
Conditions: Heart Failure
Interventions: DEVICE: CardioPumlonary Management System (CPM)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Role of ABUS as an Alternative to Breast MRI in Assessing Response to Neoadjuvant Chemotherapy
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: DIAGNOSTIC_TEST: Automated whole breast ultrasound|DIAGNOSTIC_TEST: Breast MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Cognitive Self-Management Intervention for Persons With Multiple Sclerosis: Adapting Web-based Technology
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: BEHAVIORAL: Eight weekly 90-minute group educational sessions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Is Myocardial Revascularization Really Necessary in Patients With ≥50-70% Coronary Stenosis Undergoing Valvular Surgery?
Status: COMPLETED
Conditions: Coronary Artery Disease|Heart Valve Diseases
Interventions: PROCEDURE: Valvular interventions
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of Ramucirumab (IMC-1121B) in Participants With Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer|Metastatic Breast Cancer
Interventions: BIOLOGICAL: Ramucirumab|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adjuvant Doxorubicin/Cyclophosphamide and Paclitaxel Plus Sorafenib Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Doxorubicin|DRUG: Cyclophosphamide|DRUG: Paclitaxel|DRUG: Sorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Music on Cardiopulmonary Exercise Capacity in Heart Failure Patients
Status: RECRUITING
Conditions: Heart Failure
Interventions: OTHER: Music
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Confirm if Fezolinetant Helps Reduce Hot Flashes in Women With Breast Cancer Who Are Having Hormone Therapy
Status: RECRUITING
Conditions: Hot Flashes
Interventions: DRUG: Fezolinetant|DRUG: Placebo|DRUG: Tamoxifen|DRUG: Aromatase inhibitor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Palliative Care Coaching for Families With Rare Advanced Lung Diseases
Status: COMPLETED
Conditions: Lung Diseases|Rare Non-Neoplastic Disorder
Interventions: BEHAVIORAL: Intervention FamPALcare
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Allium Sativum Oil as Alternative Non-vital Pulpotomy Medicament in Primary Teeth
Status: COMPLETED
Conditions: Non-Vital Tooth
Interventions: DRUG: Formocresol|DRUG: Allium Sativum Oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Security and Efficacy of Dorilax® (Fixed Association of Paracetamol 350 mg, Carisoprodol 150 mg and Caffeine 50 mg) Plus Thermal Band Compared to Placebo Plus Thermal Band in the Treatment of Acute Low Back Pain.
Status: WITHDRAWN
Conditions: Low Back Pain
Interventions: DEVICE: Thermal Band|DRUG: Dorilax®|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Split Mouth Trial to Compare Microneedles vs. Standard Needles in Dental Anaesthetic Delivery
Status: COMPLETED
Conditions: Dental Pain|Anesthesia, Local
Interventions: DEVICE: Microneedle Device (Experimental)|DEVICE: 30-gauge Short Hypodermic Needle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Broadband Collaborative Pulse Ablation Instrument Treating Malignant Pulmonary Nodules
Status: NOT_YET_RECRUITING
Conditions: Lung Neoplasm Malignant|Secondary Lung Cancer
Interventions: DEVICE: broadband collaborative pulse ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vigabatrin for Cocaine and Alcohol Dependence
Status: TERMINATED
Conditions: Alcoholism|Cocaine Dependence
Interventions: DRUG: Vigabatrin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: V Shaped Plate Vs Champy Technique in Mandibular Angle Fractures
Status: NOT_YET_RECRUITING
Conditions: Fractures, Bone
Interventions: PROCEDURE: Open reduction and internal fixation of mandibular angle fracture using V shaped plate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Exploring the Immune Response to SARS-CoV-2 modRNA Vaccines in Patients With Secondary Progressive Multiple Sclerosis (AMA-VACC)
Status: COMPLETED
Conditions: Secondary Progressive Multiple Sclerosis
Interventions: DRUG: BAF312|DRUG: Baseline disease modifying therapies (DMTs)|BIOLOGICAL: BNT162|BIOLOGICAL: mRNA-1273
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: DapagliFLOzin in Renal AL Amyloidosis (FLORAL)
Status: NOT_YET_RECRUITING
Conditions: Renal AL Amyloidosis
Interventions: DRUG: Dapagliflozin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Getting to Zero Among Black MSM in the American South
Status: ENROLLING_BY_INVITATION
Conditions: HIV Infections
Interventions: OTHER: Health Equity|BEHAVIORAL: Social Media Influencers|BEHAVIORAL: Intersectional Stigma Reduction|BEHAVIORAL: Peer Support|OTHER: Standard-of-care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Studying Genes in Samples From Younger Patients With Ovarian or Testicular Sex Cord Stromal Tumors
Status: COMPLETED
Conditions: Childhood Germ Cell Tumor|Leydig Cell Tumor|Ovarian Cancer
Interventions: GENETIC: RNA analysis|GENETIC: gene expression analysis|GENETIC: mutation analysis|GENETIC: reverse transcriptase-polymerase chain reaction|OTHER: laboratory biomarker analysis|OTHER: medical chart review
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of a Multispecies Probiotics on Autism Symptoms and the Quality of Life in Children
Status: NOT_YET_RECRUITING
Conditions: Autism Spectrum Disorder
Interventions: DIETARY_SUPPLEMENT: Multispecies probiotics|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of a Novel Type 3 Oral Poliomyelitis Vaccine in Panama
Status: RECRUITING
Conditions: Poliomyelitis
Interventions: BIOLOGICAL: Novel Live Attenuated Type 3 Oral Poliomyelitis Vaccine (nOPV3)|BIOLOGICAL: Sabin Monovalent Oral Poliomyelitis Vaccine Type 3 (mOPV3)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of Daclizumab in Participants With RRMS Switching From Natalizumab
Status: TERMINATED
Conditions: Relapsing-Remitting Multiple Sclerosis (RRMS)
Interventions: DRUG: Daclizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Post-meal Insulin Dosing With Adjuvant Pre-meal Pramlintide in Children With Type 1 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus
Interventions: DRUG: Insulin|DRUG: Pramlintide + Insulin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Perioperative Analgesia Using Gabapentin in Head and Neck Cancer Surgery
Status: TERMINATED
Conditions: Cancer of Head and Neck|Narcotic Use
Interventions: DRUG: Gabapentin|DRUG: Placebo - Concentrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of Clofarabine in Japanese Patients With Acute Myeloid Leukemia (AML)
Status: COMPLETED
Conditions: Acute Myelogenous Leukemia
Interventions: DRUG: clofarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: General Health, Attitudes, and Activity in Self-directed Exercise in Patients With Cystic Fibrosis (GAINS-CF)
Status: UNKNOWN
Conditions: Cystic Fibrosis
Interventions: BEHAVIORAL: Team and Technology
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparation Between Two Surgical Techniques With Acellular Dermal Matrix in Treatment of Gingival Recessions
Status: COMPLETED
Conditions: Gingival Recession|Gingival Diseases|Mouth Diseases|Periodontal Atrophy|Periodontal Diseases|Stomatognathic Diseases
Interventions: PROCEDURE: root coverage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized Multicenter Double-Blind CT to Evaluate the Efficacy and Safety of Mycophenolate Mofetil . . .
Status: TERMINATED
Conditions: Interstitial Cystitis|Painful Bladder Syndrome
Interventions: DRUG: Mycophenolate Mofetil|DRUG: Mycofenolate Mofetil (MMF)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Hospital for Special Surgery Knee Arthroplasty Cohort
Status: ACTIVE_NOT_RECRUITING
Conditions: Knee Arthroplasty
Interventions: PROCEDURE: Baseline Questionnaire|PROCEDURE: Operative Data|PROCEDURE: Intra-operative data will be collected post-operatively|PROCEDURE: In-hospital post-operative data will be collected|PROCEDURE: Satisfaction data will be extracted from Press/Ganey and on follow-up questionnaires|PROCEDURE: Cost Data|PROCEDURE: Follow-up questionnaires
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Early Detection of Patients at Risk of Developing Anthracycline Cardiotoxicity With TEP/CT -FDG
Status: RECRUITING
Conditions: Lymphoma, Non-Hodgkin|Lymphoma, Hodgkin
Interventions: OTHER: intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: "Get up" - The Sleep Study in Oppegard
Status: COMPLETED
Conditions: Sleep Initiation and Maintenance Disorders
Interventions: BEHAVIORAL: Sleep Restriction Therapy/Stimulus Control|OTHER: Discussions about adverse cognitions about sleep|OTHER: Psychoeducative advice about how to improve sleep
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of an Oral Stimulation Protocol in Preterm Infants to Shorten the Period Between Enteral and Oral Nutrition
Status: COMPLETED
Conditions: Infant, Premature, Diseases
Interventions: PROCEDURE: Manual oral stimulation protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of a Food Supplement With Standardized Menthol, Limonene, and Gingerol Content in Patients With Irritable Bowel Syndrome
Status: COMPLETED
Conditions: Irritable Bowel Syndrome|Irritable Bowel Syndrome With Diarrhea|Irritable Bowel Syndrome With Constipation|Irritable Bowel Syndrome Mixed
Interventions: DIETARY_SUPPLEMENT: Food Supplement With Standardized Menthol, Limonene, and Ginger|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial Comparing Oseltamivir With Placebo And Zanamivir With Control As First Line Treatment For Human Swine Influenza Infection
Status: TERMINATED
Conditions: Upper Respiratory Tract Infection|Influenza
Interventions: DRUG: Oseltamivir|DRUG: Zanamivir|DRUG: Placebo of Oseltamivir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Norgestimate/Ethinyl Estradiol on Bone Density in Pediatric Subjects With Anorexia Nervosa
Status: COMPLETED
Conditions: Osteoporosis
Interventions: DRUG: norgestimate/ethinyl estradiol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Probiotic Use in Children Undergoing Hematopoietic Stem Cell Transplantation (HSCT)
Status: COMPLETED
Conditions: Hematopoietic Organs; Disorder
Interventions: DRUG: Lactobacillus plantarum strains 299 and 299v
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Synergistic Effect of Vitamin D Supplementation in Patients With Vitiligo and Vitamin D Deficiency
Status: COMPLETED
Conditions: Vitamin D Deficiency|Vitiligo
Interventions: DRUG: cholecalciferol (vitamin D3)|PROCEDURE: Phototherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Disease Control and Safety in Patients With Relapsing Remitting Multiple Sclerosis (RRMS) Switching From Natalizumab to Fingolimod
Status: TERMINATED
Conditions: Relapsing Remitting Multiple Sclerosis (RRMS)
Interventions: DRUG: Fingolimod|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of HOFA Versus Hydrocolloid Dressings in the Prevention of PUs in Critically Ill Prone Patients
Status: UNKNOWN
Conditions: Prone Position|Pressure Ulcer
Interventions: OTHER: Hyperoxygenated fatty acids|OTHER: Hydrocolloid dressings
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Ropivacaine Though Laterosternal Catheters After Cardiac Surgery
Status: COMPLETED
Conditions: Cardiac Surgery
Interventions: DRUG: Ropivacaine (in one arm); catheterization (in both).
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: A Phase 1 Dose Escalation Study of Intravenous VX-993 in Healthy Adults
Status: RECRUITING
Conditions: Pain
Interventions: DRUG: VX-993|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy Of Autologous Epidermal Cell Suspension And Silver Sulfadiazine Ointment In Burn
Status: COMPLETED
Conditions: Burn
Interventions: BIOLOGICAL: Autologous epidermal cell suspension|DRUG: Silver sulfadiazine ointment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Concomitant Renal and Urinary Bladder Allograft Transplantation
Status: RECRUITING
Conditions: Chronic Kidney Diseases|Bladder Dysfunction|Bladder Absence|Posterior Urethral Valve|Neurogenic Bladder|Bladder Exstrophy|Bladder Outlet Obstruction|Failure, Kidney|Transplant
Interventions: PROCEDURE: Concomitant Renal and Urinary Bladder Allograft Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study for Evaluation of the Efficacy and Safety of SI-614 Ophthalmic Solution in Patient With Dry Eye
Status: COMPLETED
Conditions: Dry Eye Disease
Interventions: DRUG: SI-614|DRUG: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sevoflurane Sedation in Patients With Septic Shock
Status: NOT_YET_RECRUITING
Conditions: Shock, Septic
Interventions: DRUG: Sevoflurane|DRUG: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study for Assessment of the Efficacy of Gabapentin (Carbatin and Neurontin) in Patients With Neuropathy Pain
Status: COMPLETED
Conditions: Neuropathy|Pain
Interventions: DRUG: Carbatin|DRUG: Neurontin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: LANDMARC Study: a Study With Focus on Aorta Ascendens
Status: NOT_YET_RECRUITING
Conditions: Aortic Diseases|Aortic Aneurysm|Aortic Dissection|Aortic Aneurysm, Thoracic|Aortic Dilatation|Aortic Elongation
Interventions: OTHER: 4D-flow MR & CT-scan
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Endoscopic Decompression Versus Microscopic Decompression in Lumbar Canal Stenosis
Status: NOT_YET_RECRUITING
Conditions: Lumbar Spinal Stenosis
Interventions: PROCEDURE: Endoscopic Decompressive Laminectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Correlation of Soluble Suppression of Tumorigenicity 2 (ST2) With Golimumab (MK-8259) Response in Participants With Ulcerative Colitis (UC) (MK-8529-022).
Status: COMPLETED
Conditions: Colitis, Ulcerative
Interventions: BIOLOGICAL: Golimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Integration of mHEALTH Into the Care of Patients With Sickle Cell Disease to Increase Hydroxyurea Utilization
Status: COMPLETED
Conditions: Sickle Cell Disease
Interventions: BEHAVIORAL: InCharge Health mobile application|BEHAVIORAL: HU Toolbox mobile application
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Project CONTINUITY: Promoting Evidence-Based Cancer Screening Among Underserved Women
Status: RECRUITING
Conditions: Cervical Cancer Screening Methods
Interventions: BEHAVIORAL: Participant Choice of HPV Self-Test|BEHAVIORAL: Survey: Participant cancer history and cervical cancer prevention/screening knowledge|BEHAVIORAL: Participant Choice of Standard of Care in-clinic Pap-test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: KRT-232 in Subjects With Relapsed or Refractory Small Cell Lung Cancer
Status: TERMINATED
Conditions: Small-cell Lung Cancer|Small Cell Lung Carcinoma|Small Cell Lung Cancer Extensive Stage|Small Cell Lung Cancer Recurrent
Interventions: DRUG: KRT-232
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Position Intervention to Reduce Hypoxemia in Sedation Patients
Status: NOT_YET_RECRUITING
Conditions: Hypoxemia|Sedation Complication|Emergencies|Airway Remodeling
Interventions: OTHER: The position adopted when patients undergoing procedure or surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: 12-Step Facilitation/MET/CBT (InTEGRA) vs. MET/CBT for Youth With Alcohol and Other Drug Use Disorder
Status: NOT_YET_RECRUITING
Conditions: Alcohol Use Disorder|Cannabis Use Disorder
Interventions: BEHAVIORAL: InTEGRA|BEHAVIORAL: MET/CBT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Virtual Reality Exposure Therapy Versus Exposure in Vivo for Social Phobia
Status: COMPLETED
Conditions: Social Anxiety Disorder|Social Phobia
Interventions: BEHAVIORAL: Exposure in vivo|BEHAVIORAL: Virtual Reality Exposure Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of an Automated Insulin Delivery System in Adult Participants With Type 1 Diabetes Mellitus During Meal Challenges
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus
Interventions: DEVICE: AID System|DRUG: Insulin Lispro
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: The Effect of Quetiapine XR in Depressive Patients Showing Aberrant N100 Amplitude Slope
Status: UNKNOWN
Conditions: Major Depressive Disorder
Interventions: DRUG: SSRI monotherapy|DRUG: Seroquel XR adjunctive
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of ARO-ANG3 in Participants With Homozygous Familial Hypercholesterolemia (HOFH)
Status: ACTIVE_NOT_RECRUITING
Conditions: Homozygous Familial Hypercholesterolemia
Interventions: DRUG: ARO-ANG 3 Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Aromatherapy Massage on Pain and Anxiety After Mastectomy
Status: UNKNOWN
Conditions: Acute Pain|Anxiety|Mastectomy|Massage Therapy|Aromatherapy
Interventions: PROCEDURE: Aromatherapy massage with sesame- lavender oil mixed|PROCEDURE: Aromatherapy massage with sesame oil|PROCEDURE: Massage with parraffin oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Progesterone for the Prevention of Miscarriage and Preterm Birth in Women With First Trimester Bleeding: PREEMPT Trial
Status: COMPLETED
Conditions: Miscarriage|Preterm Birth
Interventions: DRUG: Progesterone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A New Mindfulness Intervention Called Mindfulness Based Swinging Technique (MBST) for Women With Breast Cancer
Status: COMPLETED
Conditions: Anxiety|Stress|Self Efficacy|Depression|Breast Cancer Female|Hopefulness
Interventions: BEHAVIORAL: Mindfulness based Swinging Effect Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy of Internet and Smartphone Application-delivered Tinnitus Retraining Therapy
Status: WITHDRAWN
Conditions: Tinnitus
Interventions: DRUG: Ginkgo biloba|BEHAVIORAL: modified TRT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Evaluate the Efficacy and Safety of GV1001 in Alzheimer Patients
Status: COMPLETED
Conditions: Alzheimer Disease
Interventions: DRUG: Normal Saline 0.9%|DRUG: GV1001 0.56 mg|DRUG: GV1001 1.12 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of Full Contour Zirconia Chairside CAD/CAM Crowns
Status: RECRUITING
Conditions: Dental Disorders Hard Tissues of Teeth|Dental Diseases
Interventions: DEVICE: Crowns self-adhesively luted|DEVICE: Crowns conventionally cemented
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dose-Response, Safety and Efficacy of Febuxostat in Subjects With Gout
Status: COMPLETED
Conditions: Gout
Interventions: DRUG: Placebo|DRUG: Febuxostat|DRUG: Febuxostat|DRUG: Febuxostat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety and Efficacy of Abatacept for Treating Chronic Cytopenia in Cytotoxic T-Lymphocyte Antigen 4 (CTLA4) Haploinsufficiency
Status: WITHDRAWN
Conditions: CTLA4 Haploinsufficency|Chronic Cytopenia
Interventions: DRUG: abatacept|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Lithia Water Study: Effects of Lithia Water on BDNF and Oxidative Stress Markers in Healthy Male Participants
Status: TERMINATED
Conditions: Oxidative Stress
Interventions: DIETARY_SUPPLEMENT: Lithia water|DIETARY_SUPPLEMENT: Natural spring water with negligible lithium levels
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Surgical Outcome and Differences on Histopathology in Patients With Alcoholic & Non Alcoholic Chronic Pancreatitis
Status: COMPLETED
Conditions: Pancreatitis, Chronic
Interventions: PROCEDURE: Frey's procedure/Pylorus preserving pancreatoduodenectomy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Influence of Respiratory and Exercise Therapy on Oxygen Uptake, Quality of Life and Right Ventricular Function in Severe Pulmonary Hypertension
Status: COMPLETED
Conditions: Pulmonary Hypertension
Interventions: OTHER: respiratory and exercise therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Dorzolamide+Timolol Multidose Preservative-free vs Dorzolamida+Timolol BAK Preserved Efficacy and Safety
Status: RECRUITING
Conditions: Glaucoma, Open-Angle|Ocular Hypertension
Interventions: DRUG: Dorzolamide / Timolol Ophthalmic Solution|DRUG: dorzolamide/timolol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acoart SCB SFA: Sirolimus Coated Balloon Catheter in the Treatment of Femoropopliteal Artery Stenosis
Status: RECRUITING
Conditions: Peripheral Artery Disease
Interventions: DEVICE: Sirolimus-eluting balloon catheter|DEVICE: Paclitaxel-eluting balloon catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pre-exposure Prophylaxis for SARS-Coronavirus-2
Status: COMPLETED
Conditions: COVID-19|Corona Virus Infection|ARDS|Acute Respiratory Distress Syndrome
Interventions: DRUG: Hydroxychloroquine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Effect of Combined Glenohumeral Joint and Subdeltoid Bursa Injection With Platelet-rich Plasma (PRP), Corticosteroid, and Normal Saline in Addition to Physical Therapy for Treatment of Frozen Shoulder
Status: RECRUITING
Conditions: Frozen Shoulder|Adhesive Capsulitis|Shoulder|Platelet-rich Plasma|Corticosteroid|Injection
Interventions: OTHER: PRP injection (PRP group)|OTHER: Corticosteroid injection (CS group)|OTHER: Normal saline injection (NS group)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Carbohydrate in Diet and Supplements on the Gastrointestinal Tolerability of LIK066
Status: COMPLETED
Conditions: Obesity
Interventions: DRUG: LIK066|DIETARY_SUPPLEMENT: Carbohydrate 50%|DIETARY_SUPPLEMENT: Carbohydrate 25%|DIETARY_SUPPLEMENT: Carbohydrate 8%|DIETARY_SUPPLEMENT: Carbohydrate 0%|DIETARY_SUPPLEMENT: Psyllium|DIETARY_SUPPLEMENT: Calcium carbonate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Assessment of Safety, Tolerability, Immunogenicity, and Pharmacokinetics of AZD3427
Status: COMPLETED
Conditions: Heart Failure
Interventions: DRUG: AZD3427|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Ability of 2% Lidocaine Gel to Reduce the Discomfort of Urethral Catheterization
Status: COMPLETED
Conditions: Urinary Tract Infection
Interventions: DRUG: 2% lidocaine gel|DRUG: Health Care Lubricating Jelly
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Electro Neuro Adaptive Regulator in Patients With Fibromyalgia
Status: COMPLETED
Conditions: Fibromyalgia
Interventions: OTHER: Electro Neuro adaptative Regulator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy + Anakinra in Patients With Pancreatic Adenocarcinoma (PDAC)
Status: NOT_YET_RECRUITING
Conditions: Pancreatic Adenocarcinoma
Interventions: DRUG: Anakinra
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of an Early Warning System on the Prognosis of Patients With Hematological Malignancies Receiving Intensive Chemotherapy With or Without Hematopoietic Cell Transplantation.
Status: NOT_YET_RECRUITING
Conditions: Leukemia|Lymphoma|Multiple Myeloma
Interventions: OTHER: Real-time calculation of the NEWS with ICU admission if NEWS ≥ 7.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Potential Association of Long Non-coding RNA (NEAT1 and MALAT1) in the Process of Epithelial-mesenchymal Transition in Periodontitis
Status: ACTIVE_NOT_RECRUITING
Conditions: Periodontal Disease, AVDC Stage 3and 4|Epithelial Mesenchymal Transition|Long Noncoding RNA
Interventions: OTHER: periodontitis challenge
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Gynecological Follow-up of Patients With Autoimmune Disease or Inflammatory Rheumatism
Status: RECRUITING
Conditions: Arthritis, Rheumatoid|Spondylitis, Ankylosing|Lupus Erythematosus, Systemic|Scleroderma, Systemic|Sjogren's Syndrome|Mixed Connective Tissue Disease
Interventions: BEHAVIORAL: Questionnaire
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical Trial of Topically-applied Glyceryl Trinitrate (GTN) for the Treatment of Erectile Dysfunction (ED)
Status: COMPLETED
Conditions: Erectile Dysfunction
Interventions: DRUG: Glyceryl trinitrate|DRUG: MED Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of HCP1102 Capsule
Status: COMPLETED
Conditions: Asthma With Allergic Rhinitis
Interventions: DRUG: HCP1102+HGP0711Placebo|DRUG: HCP1102Placebo+HGP0711
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Additive Anti-inflammatory Action for Aortopathy & Arteriopathy (Sivelestat) VI
Status: NOT_YET_RECRUITING
Conditions: Aortic Dissection|Systemic Inflammatory Response Syndrome
Interventions: DRUG: Sivelestat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Holmium Laser Ablation of the Prostate (HoLAP) Versus KTP Laser Vaporization of the Prostate
Status: TERMINATED
Conditions: Benign Prostatic Hyperplasia
Interventions: OTHER: Comparison study between KTP and HoLAP for BPH
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Fresh Versus Frozen Stool for Fecal Transplant in Children
Status: COMPLETED
Conditions: Clostridium Difficile
Interventions: BIOLOGICAL: Transplant uses frozen anonymous stool|BIOLOGICAL: Transplant uses fresh familial stool
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SILS™ Port Laparoscopic Cholecystectomy Post Market Study
Status: COMPLETED
Conditions: Gallbladder Disease
Interventions: PROCEDURE: SILS™ port laparoscopic cholecystectomy|PROCEDURE: Four Port Laparoscopic Cholecystectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Physiological Effects of Grape Seed Extract in Diastolic Heart Failure
Status: COMPLETED
Conditions: Diastolic Heart Failure|Hypertensive Heart Disease|Heart Failure With Preserved Ejection Fraction|Hypertension|Oxidative Stress
Interventions: DRUG: grape seed extract (MegaNatural BP, Polyphenolics, Inc.)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Leronlimab (PRO 140) Combined With Carboplatin in Patients With CCR5+ mTNBC
Status: UNKNOWN
Conditions: Triple Negative Breast Neoplasms
Interventions: DRUG: 350 mg leronlimab|DRUG: 525 mg leronlimab|DRUG: 700 mg leronlimab|DRUG: AUC 5 Carboplatin|DRUG: Maximum Tolerated Dose (MTD) of leronlimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HIV Non-Occupational Post-Exposure Prophylaxis
Status: COMPLETED
Conditions: Human Immunodeficiency Virus
Interventions: DRUG: Single Dose Elivitegravir (150mg), Combicistat (150mg), Emtricitabine (200mg), Tenofovir DF (300mg)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION