pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Stereotactic Ablative Radiotherapy for Hepatocellular Carcinoma ≤ 5 cm
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma
Interventions: RADIATION: Stereotactic ablative radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lifestyle Intervention in Overweight/Obese Chronic Low Back Pain (CLBP) Patients: an International Multi-center RCT
Status: RECRUITING
Conditions: Overweight or Obesity|Chronic Low-back Pain
Interventions: BEHAVIORAL: Physiotherapy intervention, including behavioral weight reduction program combined with pain neuroscience education and cognition-targeted exercise therapy.|BEHAVIORAL: Physiotherapy intervention, including pain neuroscience education and cognition-targeted exercise therapy alone.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dilation and Curettage Versus Operative Hysteroscopy for Missed Abortion
Status: RECRUITING
Conditions: Spontaneous Abortion|Missed Abortion|Intrauterine Adhesion|Retained Products of Conception
Interventions: PROCEDURE: Operative Hysteroscopy|PROCEDURE: D&C|PROCEDURE: Operative Hysteroscopy - safety and feasibility
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Hypno-analgesia on Pain During a Lumbar Puncture for Diagnosis of Alzheimer's Disease
Status: WITHDRAWN
Conditions: Cognitive Impairment|Alzheimer Disease
Interventions: OTHER: Relational care|OTHER: Hypno-analgesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Autologous Blood Patch Injection Versus BioSentry Hydrogel Tract Plug in the Reduction of Pneumothorax Risk Following Lung Biopsy Procedures
Status: COMPLETED
Conditions: Lung Biopsy
Interventions: OTHER: ABPI|DEVICE: BioSentry (formerly known as Bio-Seal) hydrogel Tract Plug
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Severe Renal Disease Study in Fabry Patients Treated With Fabrazyme
Status: TERMINATED
Conditions: Fabry Disease|Chronic Kidney Disease, Stage IV (Severe)
Interventions: BIOLOGICAL: Fabrazyme (agalsidase beta)|BIOLOGICAL: Fabrazyme (agalsidase beta)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Postoperative Analgesic Nerve Block Ropivacaine Concentrations
Status: COMPLETED
Conditions: Total Hip Arthroplasty|Postoperative Pain
Interventions: DRUG: 0.1% or 0.2% ropivacaine nerve blocks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Assessment of Autologous Bone-marrow Derived Adult Mesenchymal Stem Cell Therapy in Patients With Anoxic(or Hypoxic) Brain Injury Pilot Trial
Status: UNKNOWN
Conditions: Anoxic Brain Injury
Interventions: BIOLOGICAL: HYNR-CS inj.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Determining the Extent of Diffusion Tensor Abnormalities in Focal Cortical Dysplasia
Status: COMPLETED
Conditions: Focal Cortical Dysplasia|Epilepsy
Interventions: PROCEDURE: Magnetoencephalography|PROCEDURE: MR imaging|PROCEDURE: Diffusion Tensor Imaging
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of Avutometinib and Defactinib in People With Thyroid Cancer
Status: RECRUITING
Conditions: Thyroid Cancer
Interventions: DRUG: Avutometinib|DRUG: Defactinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy, Surgery, Radiation Therapy and Bone Marrow or Peripheral Stem Cell Transplantation in Treating Patients With Primary CNS Germ Cell Tumors
Status: UNKNOWN
Conditions: Brain and Central Nervous System Tumors
Interventions: BIOLOGICAL: filgrastim|DRUG: carboplatin|DRUG: cyclophosphamide|DRUG: etoposide|DRUG: thiotepa|PROCEDURE: autologous bone marrow transplantation|PROCEDURE: bone marrow ablation with stem cell support|PROCEDURE: conventional surgery|PROCEDURE: peripheral blood stem cell transplantation|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bufei Recipe Reduces the Incidence Rate of COPD
Status: NOT_YET_RECRUITING
Conditions: Preserved Ratio Impaired Spirometry
Interventions: DRUG: Bufei Recipe|DRUG: Bufei Recipe placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Low-level Laser Therapy in Distal Radius Fractures
Status: COMPLETED
Conditions: Colles' Fracture
Interventions: OTHER: Low-Level Laser Therapy|OTHER: Placebo Low Level Laser therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: LIME Study (LFB IVIg MMN Efficacy Study)
Status: COMPLETED
Conditions: Motor Neuron Disease
Interventions: DRUG: Biological : I10E (Human normal Immunoglobulin for intravenous administration 100mg/mL)|DRUG: Biological: Kiovig® (Human normal Immunoglobulin for intravenous administration 100mg/mL)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Quantitative Evaluation of [18F]T807 as a Potential PET Radioligand for Imaging Tau in Patients With Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer's Disease (AD)
Interventions: DRUG: [18F]T807
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study of ANV419 Alone or in Combination With Approved Treatments in Patients With Multiple Myeloma (OMNIA-2)
Status: TERMINATED
Conditions: Multiple Myeloma|Relapsed Cancer|Refractory Multiple Myeloma|Adult Disease|Hematologic Diseases
Interventions: DRUG: ANV419|DRUG: Lenalidomide with low-dose dexamethasone|DRUG: Daratumumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Effect of CSJ117 on Symptoms, Pharmacodynamics and Safety in Patients With COPD
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: CSJ117|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Repeat Intranodal Injection of Memgen's Cancer Vaccine, Ad-ISF35, in Subjects With Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL)
Status: TERMINATED
Conditions: Chronic Lymphocytic Leukemia|Small Lymphocytic Lymphoma
Interventions: BIOLOGICAL: ISF35
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Effect of Gabapentin Enacarbil on Simulated Driving in Healthy Subjects
Status: COMPLETED
Conditions: Restless Legs Syndrome (RLS)
Interventions: DRUG: gabapentin enacarbil|DRUG: diphenhydramine|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Wearable Defibrillator in Heart-Failure Patients
Status: COMPLETED
Conditions: Heart Failure|Ventricular Dysfunction|Sudden Death|Sudden Cardiac Arrest|Ventricular Tachycardia|Ventricular Fibrillation
Interventions: DEVICE: wearable defibrillator (LifeVest)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Dosimetry After rhTSH or Withdrawal of Thyroid Hormone in Metastatic or Locally Advanced Thyroid Cancer
Status: TERMINATED
Conditions: Thyroid Cancer|Metastases
Interventions: DRUG: TSH stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Evaluation of CLP in Heart Failure Patients With Chronic Kidney Disease
Status: COMPLETED
Conditions: Heart Failure
Interventions: DRUG: CLP|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Del Nido Versus HTK Cardioplegia in Adult Aortic Valve Replacement
Status: ACTIVE_NOT_RECRUITING
Conditions: Aortic Valve Disease|Valve Disease, Heart|Cardiac Ischemia
Interventions: DRUG: Del Nido Cardioplegia Solution|DRUG: HTK solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Alfimeprase in Subjects With Occluded Central Catheters
Status: COMPLETED
Conditions: Thrombosis|Venous Thrombosis
Interventions: DRUG: Alfimeprase
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Sildenafil Citrate for Treatment of Growth-restricted Fetuses
Status: UNKNOWN
Conditions: Fetal Growth Restriction
Interventions: DRUG: Sildenafil Citrate 25Mg Tab|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ghrelin for Alcohol Use in Non-Treatment-Seeking Heavy Drinkers
Status: COMPLETED
Conditions: fMRI|Alcohol Drinking|Alcoholism
Interventions: DRUG: Ghrelin|DRUG: Placebo|PROCEDURE: fMRI|DRUG: Alcohol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Evaluate the Safety, Efficacy and Dose Response of GSK573719 in Combination With Fluticasone Furoate in Subjects With Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: FF/GSK573719|DRUG: FF/GSK573719|DRUG: FF/GSK573719|DRUG: FF/GSK573719|DRUG: FF/GSK573719|DRUG: FF|DRUG: FF/VI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Early diAgnosis Real-Time Healthcare System for CANcer Trial
Status: RECRUITING
Conditions: Polyps|Adenoma Colon|Colorectal Polyp|Colon Polyp|Polyps of Colon
Interventions: DEVICE: CADDIE - Computer Aided Detection and Diagnosis for Intelligent Endoscopy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study Looking at the Safety, Tolerability and Efficacy of the Combination of the Study Drugs GLPG2451 and GLPG2222 With or Without GLPG2737 in Patients With Cystic Fibrosis.
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: GLPG2451 dose regimen A|DRUG: GLPG2451 dose regimen B|DRUG: GLPG2222|DRUG: GLPG2737
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Video Education to the Febrile Child on the Knowledge, Attitudes and Behaviors of the Parents.
Status: COMPLETED
Conditions: Fever|Child, Only|Approach-Approach Conflict|Parents
Interventions: OTHER: video education|OTHER: the routine procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: PDR001 Plus Imatinib for Metastatic or Unresectable GIST
Status: COMPLETED
Conditions: Gastrointestinal Stromal Tumors
Interventions: DRUG: PDR001, Imatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Biobehavioral Pain Management in TMD
Status: COMPLETED
Conditions: Temporomandibular Joint Disorder
Interventions: BEHAVIORAL: Cognitive Therapy for Catastrophizing|BEHAVIORAL: Behavioral Therapy for Sleep Continuity Disturbance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of AZD9291 in NSCLC Patients Harboring T790M Mutation Who Failed EGFR TKI and With Brain and/or LMS
Status: UNKNOWN
Conditions: Non-Small Cell Lung Cancer With EGFR T790M Mutation|With Brain and/or Leptomeningeal Metastasis|Failed Tyrosine Kinase Inhibitors
Interventions: DRUG: AZD9291
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Alternative Dosing Of Niraparib To Decrease Dose Interruption In First Line Maintenance Treatment For Ovarian Cancer
Status: RECRUITING
Conditions: Ovarian Cancer|Stage III Ovarian Cancer|Stage IV Ovarian Cancer|High Grade Ovarian Serous Adenocarcinoma
Interventions: DRUG: Niraparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Self-Management and Recovery Technology Psychosocial Intervention Trial
Status: COMPLETED
Conditions: Schizophrenia|Affective Disorders, Psychotic|Psychotic Disorders
Interventions: BEHAVIORAL: Health intervention|BEHAVIORAL: Social intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Oral Once-Daily Vonoprazan (TAK-438) in Participants With Erosive Esophagitis
Status: COMPLETED
Conditions: Erosive Esophagitis
Interventions: DRUG: Vonoprazan|DRUG: Lansoprazole|DRUG: Vonoprazan Placebo|DRUG: Lansoprazole Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Varenicline on Blood-Oxygen-Level Dependent (BOLD) Functional Magnetic Resonance Imaging (fMRI) Activation on Smokers
Status: COMPLETED
Conditions: Nicotine Dependence
Interventions: DRUG: varenicline
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Chicken Extract and Collagen on Mobility
Status: COMPLETED
Conditions: Knee Osteoarthritis|Muscle Loss
Interventions: DIETARY_SUPPLEMENT: Collagen hydrolysate and chicken extract
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: DFD06 Cream vs Clobetasol Propionate Cream, 0.05% Hypothalamic- Pituitary-Adrenal (HPA) Axis Suppression Study in Patients With Moderate to Severe Plaque Psoriasis
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: DFD06 Cream|DRUG: Clobetasol Propionate Cream 0.05%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CPP Versus PFC to Correct Coagulation Disorders in Adult Neurosurgical Patients
Status: COMPLETED
Conditions: Intracranial Hemorrhages
Interventions: DRUG: Prothrombin Complex Concentrate|BIOLOGICAL: Fresh Frozen Plasma
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Autologous CD8+ SLC45A2-Specific T Lymphocytes With Cyclophosphamide, Aldesleukin, and Ipilimumab in Treating Patients With Metastatic Uveal Melanoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Malignant Neoplasm in the Liver|Metastatic Uveal Melanoma
Interventions: BIOLOGICAL: Aldesleukin|BIOLOGICAL: Autologous CD8+ SLC45A2-specific T Lymphocytes|DRUG: Cyclophosphamide|BIOLOGICAL: Ipilimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Azacitidine After Allo Blood And Marrow Transplantation (BMT) for Chronic Myelogenous Leukemia (CML)
Status: COMPLETED
Conditions: Stem Cell Transplantation|Leukemia
Interventions: DRUG: Fludarabine|DRUG: Busulfan|DRUG: Thymoglobulin|DRUG: Azacitidine|PROCEDURE: Stem Cell Transplant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Biomarkers of Neuropathic Pain in Women Treated for Breast Cancer
Status: COMPLETED
Conditions: Neuropathic Pain|Breast Cancer
Interventions: OTHER: Cold water test|OTHER: Autonomic nervous system monitoring|OTHER: QST
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: A Prospective Study to Evaluate the Effectiveness of a Haemostatic Agent in Primary Unilateral Total Hip Arthroplasty
Status: COMPLETED
Conditions: Arthritis
Interventions: DEVICE: Vitagel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The KP Personal Shopper: A Pilot to Improve the Impact of Dietary Advice
Status: COMPLETED
Conditions: Overweight|Obesity
Interventions: BEHAVIORAL: KP Personal Shopper Visits|BEHAVIORAL: In-Office Dietitian Visits
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Thunder Trial - Local Taxan With Short Time Contact for Reduction of Restenosis in Distal Arteries
Status: UNKNOWN
Conditions: Arterial Occlusive Diseases
Interventions: DRUG: Balloon Angioplasty with or without drug administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Effect Of The Use Of Navigation In The Alignment Obtained When Performing A Total Knee Arthroplasty In Obese Patients
Status: RECRUITING
Conditions: Osteoarthritis, Knee|Obesity|Arthropathy of Knee
Interventions: DEVICE: Total knee arthroplasty implanted with GPS navigation system|DEVICE: Total knee arthroplasty implanted with standard guides.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intranasal Oxytocin Effects in Alcohol Withdrawal and Dependence; Follow-up Study
Status: COMPLETED
Conditions: Alcoholism|Substance-Related Disorders
Interventions: DRUG: intranasal oxytocin spray|OTHER: intranasal spray without oxytocin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study To Evaluate The Response To Enbrel And The Impact Of Rheumatoid Factor(RF) And Anti-Cyclic Citrullinated Peptide(Anti-CCP) In Rheumatoid Arthritis(RA) Patients
Status: COMPLETED
Conditions: Arthritis, Rheumatoid
Interventions: DRUG: Enbrel
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Impact of Intraoperative Instillation of Normothermal Saline on the Prevention of Intraoperative Hypothermia and Perioperative Morbidity of Prostatic Enucleation With Holmium Laser
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostatic Hypertrophy
Interventions: DEVICE: Fluido® Irrigation Fluid Heater System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy of Tegaserod in Opioid-induced Constipation in Patients With Non-cancer Pain.
Status: TERMINATED
Conditions: Opioid-induced Constipation
Interventions: DRUG: Tegaserod
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of LY2484595 on Pharmacokinetics in Healthy Participants
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DRUG: LY2484595|DRUG: Placebo|DRUG: Ketoconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Annatto-derived GG for Statin-associated Myopathy
Status: RECRUITING
Conditions: Myopathy; Primary
Interventions: DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: Low GG|DIETARY_SUPPLEMENT: High GG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bexagliflozin Drug/Drug Interaction Study With Digoxin
Status: COMPLETED
Conditions: Type2 Diabetes Mellitus
Interventions: DRUG: Bexagliflozin|DRUG: Digoxin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Quantitative Assessment of Blood Supply in the Gastic Conduit With Fluorescence Angiography for Esophageal Reconstruction
Status: UNKNOWN
Conditions: Esophageal Squamous Cell Carcinoma
Interventions: PROCEDURE: Fluorescence angiography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Ribociclib and Gemcitabine Hydrochloride in Treating Patients With Advanced Solid Tumors or Lymphoma
Status: TERMINATED
Conditions: Lymphoma|Solid Neoplasm
Interventions: DRUG: Gemcitabine Hydrochloride|OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacological Study|DRUG: Ribociclib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cone-beam CT Guided Microcoil Localization of Pulmonary Nodules During Video Assisted Thoracic Surgery(VATS)
Status: RECRUITING
Conditions: Lung Cancer
Interventions: OTHER: Cone Beam CT localization and placement of microcoil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effects of Teriparatide in Postmenopausal Women With Osteoporosis
Status: COMPLETED
Conditions: Postmenopausal Osteoporosis
Interventions: DRUG: teriparatide|DRUG: aldrenodate|DRUG: raloxifene
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Radiofrequency Ablation on the Results of the Genicular Nerve Number in the Treatment of Knee Osteoarthritis
Status: COMPLETED
Conditions: Osteoarthritis, Knee|Radiofrequency Ablation|Genicular Nerve
Interventions: PROCEDURE: Radiofrequency ablation of genicular nerves
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Impact of an Online Stress Management Program on In Vitro Fertilization (IVF) Outcome
Status: WITHDRAWN
Conditions: Infertility
Interventions: BEHAVIORAL: Online Stress Management Group (Upliv)|BEHAVIORAL: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Generation of Thrombin and Prediction of Deep Vein Thrombosis Post Prosthetic Orthopedic Surgery of the Lower Limbs
Status: COMPLETED
Conditions: Deep Vein Thrombosis|Total Hip Prosthesis|Knee Prosthesis
Interventions: BIOLOGICAL: Blood test|OTHER: Doppler ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Oral Status and Prevalence of Dental Trauma in Children Treated With Ritalin Due to Attention-Deficit Hyperactivity Disorder (ADHD)
Status: COMPLETED
Conditions: Attention Deficit Disorder With Hyperactivity|Dental Caries|Dental Occlusion, Traumatic
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Ultrasound Guided Quadratus Lumborum Block Versus Transversus Abdominis Plane Block as Postoperative Analgesia in Patients Undergoing Abdominal Cancer Surgery.
Status: UNKNOWN
Conditions: Abdominal Cancer
Interventions: OTHER: quadratus lumborum|OTHER: transversus abdominis plane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Evaluating the Potentials of Biodynamic Lighting for Home Office Workers
Status: COMPLETED
Conditions: Cognitive Performance|Sleep|Alertness
Interventions: OTHER: Biodynamic|OTHER: Active Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Comparison of Intubation Rate of Macintosh Size 2 and 3 Blades in Asian Female: a Randomised Controlled Trial
Status: COMPLETED
Conditions: Intubation;Difficult
Interventions: DEVICE: Macintosh size 2 blade|DEVICE: Macintosh size 3 blade
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Low-pressure Pneumoperitoneum Associated With Deep Pipecuronium-induced Neuromuscular Blockade on Hemodynamic Parameters for High Cardiovascular Risk Patient Undergoing General Anesthesia
Status: COMPLETED
Conditions: Residual Neuromuscular Block|Cardiovascular Diseases|Neuromuscular Blockade Monitoring
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Metabolic Impact of Prospective Controlled Mediterranean Type Diets on Prostate Cancer
Status: NOT_YET_RECRUITING
Conditions: Prostate Cancer
Interventions: OTHER: Lower-Carbohydrate Med-t-Diet|OTHER: Low-Fat Med-t-Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Utilizing Battlefield Acupuncture(BFA) to Treat Chronic Pain for Homeless and at Risk Veterans.
Status: COMPLETED
Conditions: Acupuncture|Homelessness|Pain|Veterans
Interventions: OTHER: Battlefield Acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Glucocorticoid Treatment in Transaortic Valve Replacement to Reduce the Incidence of Conduction Disturbances (GLUCO-TAVR).
Status: RECRUITING
Conditions: Heart Block|Aortic Stenosis|Bundle-Branch Block
Interventions: DRUG: Methylprednisolone|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Non-endoscopic Brushing of the Esophagus Using a Non-endoscopic Inflatable Balloon of the Esophagus in Screening for Barrett Esophagus
Status: COMPLETED
Conditions: Barrett Esophagus
Interventions: DEVICE: non-endoscopic inflatable balloon for the esophagus|OTHER: Questionnaire Administration|OTHER: Laboratory Biomarker Analysis|PROCEDURE: esophagogastroduodenoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Prehab Prior to Stem Cell Transplantation in Multiple Myeloma
Status: RECRUITING
Conditions: Multiple Myeloma|Exercise|Prehabilitation
Interventions: BEHAVIORAL: Supported Exercise|BEHAVIORAL: Standard Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Anti-OX40 Antibody (MEDI6469) in Patients With Metastatic Colorectal Cancer
Status: TERMINATED
Conditions: Colorectal Neoplasms
Interventions: DRUG: MEDI6469
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Artificial Intelligence Guided Patient Selection for Atrial Fibrillation Catheter Ablation: Randomized Clinical Trial (AI-PAFA Trial)
Status: RECRUITING
Conditions: Atrial Fibrillation
Interventions: PROCEDURE: Artificial Intelligence-based atrial fibrillation catheter ablation|PROCEDURE: Medical Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Feet Mechanical Stimulation on Cardiovascular Autonomic Profile and Inflammation in Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson's Disease|Autonomic Neuropathy|Inflammation|Hypertension
Interventions: DEVICE: Foot Mechanical Stimulation (Gondola®, CE marking n° 0476)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Volume Targeted Mask Ventilation Versus Pressure Ventilation in Preterm Infants
Status: NOT_YET_RECRUITING
Conditions: Neonatal Respiratory Distress
Interventions: PROCEDURE: Volume targeted ventilation|PROCEDURE: Pressure targeted ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Safety, Tolerability and Pharmacokinetics of Ascending Intravenous Single Dose and Repeat Dose of GSK3342830
Status: TERMINATED
Conditions: Infections, Bacterial
Interventions: DRUG: GSK3342830|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Impact of Enhanced Risk Assessments in Women With a BRCA1/2 Mutation, CARE Study
Status: ACTIVE_NOT_RECRUITING
Conditions: BRCA1/2-Associated Hereditary Breast and Ovarian Cancer Syndrome
Interventions: OTHER: Best Practice|PROCEDURE: Biospecimen Collection|OTHER: Counseling|PROCEDURE: Discussion|PROCEDURE: Genotyping|PROCEDURE: Molecular Risk Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Can Parecoxib Reduce Post-operative Ipsilateral Shoulder Pain?
Status: COMPLETED
Conditions: Shoulder Pain|Post-operative Pain
Interventions: DRUG: Parecoxib|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Congenital Cataract With Persistent Fetal Vasculature
Status: UNKNOWN
Conditions: Persistent Fetal Vasculature|Congenital Cataract
Interventions: PROCEDURE: cataract surgery cataract extraction and intraocular implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Office-based Methadone Versus Buprenorphine to Address Retention in Medication for Opioid Use Disorder Treatment.
Status: RECRUITING
Conditions: Opioid Use Disorder
Interventions: DRUG: Methadone|DRUG: Buprenorphine (BUP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of YHD001 in Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: YHD001 dose level 1|DRUG: YHD001 dose level 2|DRUG: Singulair|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment Outcomes in Chronic Hepatitis B Patients on Sequential Therapy With Tenofovir Alafenamide (TAF)
Status: COMPLETED
Conditions: Hepatitis B, Chronic
Interventions: DRUG: Tenofovir Alafenamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Brazilian Green Propolis Extract (EPP-AF) as an Adjunct Treatment for Hospitalized COVID-19 Patients (BeeCovid2)
Status: COMPLETED
Conditions: Covid19|Inflammation
Interventions: DRUG: Standardized Brazilian Green Propolis Extract|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Novel Porous Bioceramic Material as a Bone Substitute
Status: TERMINATED
Conditions: Alveolar Ridge Preservation
Interventions: DEVICE: Adaptos®-Si [0.5-1 mm] (bone grafting surgery)|DEVICE: Adaptos®-Si [1-2 mm] (bone grafting surgery)|DEVICE: Geistlich Bio-Oss (bone grafting surgery)|PROCEDURE: Tooth extraction without bone graft material|DEVICE: Adaptos® (bone grafting surgery)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study In Healthy Volunteers To Estimate The Pharmacokinetics Of Four Modified-Release Formulations Of Dimebon (Latrepirdine)
Status: COMPLETED
Conditions: Alzheimer's Disease|Huntington Disease
Interventions: DRUG: Dimebon IR Tablet|DRUG: Dimebon MR1|DRUG: Dimebon MR2|DRUG: Dimebon MR3|DRUG: Dimebon MR4
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Observed Outcomes Associated With Fluticasone Propionate/Salmeterol Xinafoate or Inhaled Corticosteroids in Asthma Patients
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Higher-dose inhaled corticosteroids|DRUG: Low-dose fixed dose fluticasone propionate/salmeterol xinafoate combination
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Uppsala-Dalarna Dementia and Gait Project
Status: RECRUITING
Conditions: Dementia|Dementia, Mixed|Dementia Senile|Dementia of Alzheimer Type|Mild Cognitive Impairment|Subjective Cognitive Impairment
Interventions: DIAGNOSTIC_TEST: Timed Up-and-Go (TUG single-task)|DIAGNOSTIC_TEST: Timed Up-and-Go dual-task (TUGdt)|DIAGNOSTIC_TEST: Clinical functional assessment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Dexmedetomidine and Ketamine in VATS Surgery
Status: RECRUITING
Conditions: Postoperative Pain|Opioid Use
Interventions: DRUG: Ketamine Hydrochloride|DRUG: Dexmedetomidine Hydrochloride|COMBINATION_PRODUCT: dexmedetomidine Hydrochloride and Ketamine Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of INBRX-105 and INBRX-105 With Pembrolizumab in Patients With Solid Tumors Including Head and Neck Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Solid Tumors|Non-small Cell Lung Cancer|Melanoma|Head and Neck Squamous Cell Carcinoma|Gastric Adenocarcinoma|Renal Cell Carcinoma|Esophageal Adenocarcinoma|Nasopharyngeal Carcinoma|Oropharyngeal Carcinoma
Interventions: DRUG: INBRX-105 - PDL1x41BB antibody|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fasting Study of Hydrochlorothiazide Tablets 50 mg to Hydrochlorothiazide Tablets 50 mg
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Hydrochlorothiazide Tablets 50 mg|DRUG: Hydrochlorothiazide Tablets (50 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Comparing Different Amounts of Vitamin D Supplementation to Preschool Children Living in Northern and Southern Sweden
Status: COMPLETED
Conditions: Vitamin D Deficiency
Interventions: DIETARY_SUPPLEMENT: Vitamin D 25 microg/d|DIETARY_SUPPLEMENT: Vitamin D 10 microg/d|DIETARY_SUPPLEMENT: No extra vitamin D
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Cyclosporine A in Combination With Nab-Paclitaxel in Patients With Metastatic Breast Cancer
Status: COMPLETED
Conditions: Metastatic Breast Cancer
Interventions: DRUG: Cyclosporins|DRUG: nab-paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Observational Study to Evaluate the Efficacy of Sustained QUTENZA® Use in Painful Diabetic Peripheral Neuropathy
Status: NOT_YET_RECRUITING
Conditions: Peripheral Diabetic Neuropathy|Painful Diabetic Neuropathy
Interventions: DRUG: Capsaicin 8% Patch Kit,1
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Maveropepimut-S (MVP-S) and Low-Dose CPA in Patients With Platinum-Resistant Ovarian Cancer
Status: TERMINATED
Conditions: Platinum-resistant Epithelial Ovarian Cancer
Interventions: OTHER: Maveropepimut-S|DRUG: Cyclophosphamide 50mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Thoracolumbal Interfascial Plane Block Versus Erector Spinae Plane Block for Lumbar Posterior Decompression Stabilization
Status: UNKNOWN
Conditions: Lumbar Posterior Decompression
Interventions: PROCEDURE: Thoracolumbar interfacial plane (TLIP) Block|PROCEDURE: Erector Spinae Plane (ESP) Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cognitive and Physical Functions in Patients With Transient Ischemic Attack. A Randomized Controlled Trial of Physical Activity on Prescription up to One Year After the Event
Status: UNKNOWN
Conditions: Ischemic Attack, Transient
Interventions: OTHER: Physical activation on Prescription
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Effect of Vemurafenib on the Pharmacokinetics of Acenocoumarol in Patients With BRAFV600 Mutation-Positive Metastatic Malignancy
Status: COMPLETED
Conditions: Malignant Melanoma, Neoplasms
Interventions: DRUG: acenocoumarol|DRUG: vemurafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Cellular Immunotherapy in Treating Patients With High-Risk Acute Lymphoblastic Leukemia
Status: ACTIVE_NOT_RECRUITING
Conditions: B Acute Lymphoblastic Leukemia|Recurrent Acute Lymphoblastic Leukemia|Refractory Acute Lymphoblastic Leukemia
Interventions: BIOLOGICAL: CD19CAR-CD28-CD3zeta-EGFRt-expressing Tcm-enriched T-lymphocytes|BIOLOGICAL: CD19CAR-CD28-CD3zeta-EGFRt-expressing Tn/mem-enriched T-lymphocytes|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Pain Neuroscience Education and Physiotherapy in Patients Diagnosed With Spondyloarthritis
Status: RECRUITING
Conditions: Spondyloarthropathies|Ankylosing Spondylitis|Exercise Therapy|Physical Therapy Modalities|Pain Management
Interventions: OTHER: Pain education|OTHER: Exercise supervised by external focus|OTHER: Therapy by means of electrical stimulation (electro-massage)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Two Doses of Liarozole vs. Placebo for the Treatment of Lamellar Ichthyosis
Status: COMPLETED
Conditions: Ichthyosis, Lamellar
Interventions: DRUG: Liarozole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of ABT-414 in Participants With Newly Diagnosed Glioblastoma (GBM) With Epidermal Growth Factor Receptor (EGFR) Amplification
Status: COMPLETED
Conditions: Glioblastoma|Gliosarcoma
Interventions: DRUG: Temozolomide|DRUG: Depatuxizumab mafodotin|RADIATION: Radiation|DRUG: Placebo for ABT-414
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Post Phacoemulsification Aqueous Flare in Patients Using Ketorolac 0.45% 2 Times Daily (BID) and Bromfenac 0.09% 2 Times Daily (BID)
Status: COMPLETED
Conditions: Post Operative Anterior Chamber Inflammation (Flare)
Interventions: DRUG: Ketorolac Tromethamine 0.45%|DRUG: Bromfenac 0.09%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exercise for People With Peripheral Neuropathy and Diabetic Foot Ulcers - a Case Series on Feasibility and Safety
Status: COMPLETED
Conditions: Diabetes Mellitus|Foot Ulcer
Interventions: OTHER: Physical training as resistance and aerobic training.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Efficacy and Safety of Dignicap System for Preventing Chemotherapy Induced Alopecia
Status: UNKNOWN
Conditions: Chemotherapy Adjuvant|Breast Cancer
Interventions: DEVICE: Dignicap System
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Decitabine With or Without Valproic Acid in Treating Patients With Relapsed or Refractory Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Recurrent Adult Burkitt Lymphoma|Recurrent Adult Diffuse Large Cell Lymphoma|Recurrent Mantle Cell Lymphoma
Interventions: DRUG: decitabine|DRUG: valproic acid|OTHER: pharmacological study|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigating the Glycaemic and Satiating Capacity of PulseOn® Enriched Foods
Status: RECRUITING
Conditions: Glycaemic Response|Appetitive Behavior|Energy Intake
Interventions: OTHER: PulseOn|OTHER: Wheat flour control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparing Between CO2 and Phenylephrine Treatment in Patients With Progressive Lacunar Infarction (CARBOGEN Study)
Status: UNKNOWN
Conditions: Acute Ischemic Stroke
Interventions: DRUG: carbogen|DRUG: phenylephrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Efficacy and Safety of Intravenous Ferric Carboxymaltose (FCM) Versus Oral Iron for Iron Deficiency Anaemia in Pregnant Women
Status: COMPLETED
Conditions: Anaemia
Interventions: DRUG: ferrous sulphate|DRUG: Ferinject
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Moisturizer Containing Licochalcone A, Decanediol, L-carnitine and Salicylic Acid in Reducing Relapsing of Acne
Status: COMPLETED
Conditions: Acne Vulgaris|Acne
Interventions: OTHER: Moisturizer with active ingredients|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Scaling and Root Planning With Localized Delivery of Autogenous Growth Factors- Platelet Rich Fibrin (PRF)
Status: WITHDRAWN
Conditions: Periodontitis Chronic Generalized Severe|Periodontitis Chronic Generalized Moderate
Interventions: BIOLOGICAL: leukocyte platelet rich fibrin (L-PRF)|PROCEDURE: Scaling and Root Planing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose Escalation With SIB to Intraprostatic/Lymphatic GTV in High Risk Prostate Cancer
Status: COMPLETED
Conditions: Prostatic Neoplasms|Lymphatic Metastasis
Interventions: RADIATION: SIB Dose-Escalation Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Role of Traditional Chinese Medicine in the Treatment of Chronic Childhood Immune Thrombocytopenia (ITP)
Status: TERMINATED
Conditions: Childhood Chronic Immune Thrombocytopenia
Interventions: DRUG: Bu Zhong Yi Qi Tang, Zhi Xue Tang, Chuan xin lian kang yan pian mod, Tian Wang Bu xin Dan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Targeting Subclinical Motor and Cognitive Impairment in Patients With Early Onset Multiple Sclerosis
Status: RECRUITING
Conditions: Multiple Sclerosis, Relapsing-Remitting
Interventions: OTHER: personalized combined physical and cognitive intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Effect of Triferic Plus Heparin Infusion Compared to Heparin Alone on Coagulation Parameters in Hemodialysis Patients
Status: COMPLETED
Conditions: End Stage Renal Disease
Interventions: DRUG: Triferic|DRUG: Heparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment Efficacy and Safety of Low-dose Radioiodine Ablation for Intermediate-risk Differentiated Thyroid Carcinoma
Status: RECRUITING
Conditions: Papillary Thyroid Cancer
Interventions: DRUG: Radioiodine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pembrolizumab and Total Skin Electron Beam Radiotherapy in Mycosis Fungoides and Sézary Syndrome
Status: WITHDRAWN
Conditions: Cutaneous T-Cell Lymphomas
Interventions: RADIATION: TSEBT|DRUG: TSEBT and pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT