pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: VR Smoking Cessation During a Dental Hygiene Visit
Status: RECRUITING
Conditions: Smoking Cessation
Interventions: BEHAVIORAL: Experimental smoking cessation video|BEHAVIORAL: Control video|OTHER: Brochure of smoking cessation EBTs|BEHAVIORAL: Tailored text message program|OTHER: Assessment text messages
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Quadratus Lumborum Block Versus Transversus Abdominis Block
Status: NOT_YET_RECRUITING
Conditions: Postoperative Pain
Interventions: OTHER: General anesthesia|OTHER: Transverse abdominal block|OTHER: Quadratus lumborum block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Optimal Tailored Treatment for H. Pylori Infection
Status: WITHDRAWN
Conditions: Helicobacter Pylori Infection|Antibiotic Resistant Infection
Interventions: DIAGNOSTIC_TEST: Dual-priming oligonucleotide-based multiplex polymerase chain reaction (DPO-PCR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acupuncture and Acupressure in Treating Patients With Moderate or Severe Pain Related to Stage III or Stage IV Pancreatic Cancer
Status: COMPLETED
Conditions: Pain|Pancreatic Cancer
Interventions: PROCEDURE: complementary or alternative medicine procedure|PROCEDURE: pain therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Evaluate Safety, Tolerability, and Pharmacokinetics of Escalating Doses of AGS67E Given as Monotherapy in Subjects With Refractory or Relapsed Lymphoid Malignancies
Status: COMPLETED
Conditions: Relapsed Lymphoid Malignancy|Refractory Lymphoid Malignancy
Interventions: DRUG: AGS67E
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Silver-Coated vs Standard Catheter for UTI Prevention
Status: ACTIVE_NOT_RECRUITING
Conditions: UTI
Interventions: DEVICE: 2-Way Foley Urethral Urinary Catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Veliparib, Cisplatin, and Gemcitabine Hydrochloride in Treating Patients With Advanced Biliary, Pancreatic, Urothelial, or Non-Small Cell Lung Cancer
Status: TERMINATED
Conditions: Advanced Adult Primary Liver Cancer|Localized Unresectable Adult Primary Liver Cancer|Metastatic Transitional Cell Cancer of the Renal Pelvis and Ureter|Regional Transitional Cell Cancer of the Renal Pelvis and Ureter|Stage III Bladder Cancer|Stage III Pancreatic Cancer|Stage IIIA Non-small Cell Lung Cancer|Stage IIIB Non-small Cell Lung Cancer|Stage IV Bladder Cancer|Stage IV Non-small Cell Lung Cancer|Stage IV Pancreatic Cancer|Transitional Cell Carcinoma of the Bladder|Unresectable Extrahepatic Bile Duct Cancer|Unresectable Gallbladder Cancer
Interventions: DRUG: gemcitabine hydrochloride|DRUG: veliparib|OTHER: diagnostic laboratory biomarker analysis|OTHER: pharmacological study|DRUG: cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Zelavespib (PU-H71) in Subjects With AP-MPN or BP-MPN
Status: WITHDRAWN
Conditions: Accelerated Phase MPN|Blast Phase MPN
Interventions: DRUG: zelavespib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of Unrestricted Introduction of Pacifiers on Breastfeeding Duration
Status: UNKNOWN
Conditions: Lactation
Interventions: BEHAVIORAL: offer a pacifier|BEHAVIORAL: no pacifier
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Anti-infectious Therapy of Periodontitis - Comparison of Different Clinical Strategies
Status: COMPLETED
Conditions: Periodontitis
Interventions: OTHER: Q-SRP|OTHER: FMS|OTHER: FMD|OTHER: FMDP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial to Learn if REGN7999 is Safe and Well Tolerated, and How it Works in the Body of Healthy Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: REGN7999|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics of Dihydroartemisinin-Piperaquine in the Treatment of Uncomplicated Malaria in Children in Burkina Faso
Status: COMPLETED
Conditions: Uncomplicated Malaria
Interventions: DRUG: Dihydroartemisinin-Piperaquine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: The Effect of Dexmedetomidine on Airway Complications After Deep or Awake Extubation
Status: TERMINATED
Conditions: Adenotonsillar Hypertrophy|Obstructive Sleep Apnea|Tonsillitis|Adenoiditis
Interventions: DRUG: Normal Saline|DRUG: Dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Stability of Patient-specific Root-analogue Implants and Conventional Root-form Implants for Treating Non-restorable Single-rooted Maxillary Teeth
Status: UNKNOWN
Conditions: Implant Stability|Root Analog Implant|Conventional Root Form Implant|Non Restorabl Teeth
Interventions: DEVICE: Root analog implant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Replacing Refined Carbohydrates With Healthy Fats on Cardio-metabolic Markers
Status: COMPLETED
Conditions: Pre-diabetes|Metabolic Syndrome
Interventions: DIETARY_SUPPLEMENT: Active|DIETARY_SUPPLEMENT: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Sequential Chemotherapy in Treating Patients With Residual Disease Following Surgery for Stage IIB, Stage III, or Stage IV Ovarian Cancer
Status: UNKNOWN
Conditions: Ovarian Cancer
Interventions: DRUG: carboplatin|DRUG: paclitaxel|DRUG: topotecan hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: MISA to NRDS：a Multicenter Study in China
Status: COMPLETED
Conditions: Bronchopulmonary Dysplasia|Patent Ductus Arteriosus|Intraventricular Hemorrhage|Necrotizing Enterocolitis|Periventricular Leukomalacia
Interventions: PROCEDURE: Minimal Invasive surfactant administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Pre-Operative Treatment With Cryoablation and Immune Therapy in Early Stage Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: PROCEDURE: Cryoablation|DRUG: Ipilimumab|DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I Study to Assess the Effect of Itraconazole and Rifampicin on Pharmacokinetics Profile of BPI-7711
Status: COMPLETED
Conditions: NSCLC
Interventions: DRUG: BPI-7711|DRUG: BPI-7711|DRUG: Itraconazole|DRUG: Rifampicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Acupuncture Therapy in Patients With Subacromial Impingement Syndrome
Status: NOT_YET_RECRUITING
Conditions: Acupuncture|Subacromial Impingement Syndrome
Interventions: OTHER: Acupuncture|OTHER: Placebo acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Delayed Mycophenolate Mofetil in Single-Donor Islet Allotransplantation in Type 1 Diabetes
Status: COMPLETED
Conditions: Type 1 Diabetes|Hypoglycemia
Interventions: BIOLOGICAL: Allogeneic islets of Langerhans transplant
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety Study of IMOVAX Polio Vaccine in Selected Cities in China
Status: COMPLETED
Conditions: Polio|Poliomyelitis
Interventions: BIOLOGICAL: IMOVAX Polio™: Inactivated Poliomyelitis Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Cytarabine and Daunorubicin Hydrochloride or Idarubicin and Cytarabine With or Without Vorinostat in Treating Younger Patients With Previously Untreated Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Acute Myeloid Leukemia|Untreated Adult Acute Myeloid Leukemia
Interventions: PROCEDURE: Allogeneic Hematopoietic Stem Cell Transplantation|DRUG: Cytarabine|DRUG: Daunorubicin Hydrochloride|DRUG: Idarubicin|OTHER: Laboratory Biomarker Analysis|DRUG: Vorinostat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Sago-based Product on Glycaemic and Lipid Control in Diabetes
Status: RECRUITING
Conditions: Diabetes Mellitus, Type 2
Interventions: DIETARY_SUPPLEMENT: Sago starch drink|DIETARY_SUPPLEMENT: Corn starch drink
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of Real Time Colorectal Polyp Diagnosis During Colonoscopy - the VALID Colonoscopy Study
Status: COMPLETED
Conditions: Colorectal Neoplasm|Colonic Polyps
Interventions: DEVICE: Close focus HD NBI Colonoscopy System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of Biomarkers Associated With Fatigue in Patients With Early-Stage Breast Cancer Treated With Metformin or Placebo on NCIC-CTG-MA.32
Status: UNKNOWN
Conditions: Breast Cancer|Depression|Fatigue|Sleep Disorders
Interventions: DRUG: Metformin|DRUG: Placebo
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: PREDICT 2: Personalized Responses to Dietary Composition Trial 2
Status: COMPLETED
Conditions: Diabetes|Heart Diseases|Diet Habit|Diet Modification|Microbial Colonization|Healthy|Obesity|Metabolism
Interventions: OTHER: Dietary Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Dexamethasone Solution and Dexamethasone in Mucolox™
Status: COMPLETED
Conditions: Oral Lichen Planus|Mucous Membrane Pemphigoid|Pemphigus Vulgaris|Chronic Graft-versus-host-disease
Interventions: DRUG: dexamethasone 0.5mg/5ml solution|DRUG: dexamethasone 0.5mg/5ml solution in Mucolox™
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Elotuzumab With Pomalidomide, Bortezomib, and Dexamethasone in Relapsed Multiple Myeloma
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: Elotuzumab|DRUG: Pomalidomide|DRUG: Bortezomib|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dynepo Infrequent Dosing Study
Status: TERMINATED
Conditions: Anemia|Kidney Failure
Interventions: DRUG: Dynepo (Epoetin delta)|DRUG: Dynepo|DRUG: Dynepo|DRUG: Dynepo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Evaluate the Tolerability and Pharmacokinetics of a New Ultra Low Molecular Weight Heparin (RO-14) Administered Subcutaneously Increasing Single-doses to Healthy Male Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: RO-14
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety Study of LY3493269 Given as a Single Injection in Healthy Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: LY3493269 - SC|DRUG: Placebo - SC|DRUG: LY3493269 - IV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Association Between Proton Pump Inhibitors and Hematologic Toxicity of Pemetrexed
Status: COMPLETED
Conditions: Patients With Non-small Cell Lung Cancer (NSCLC) and Pleural Mesothelioma and Treated With a Pemetrexed-based Chemotherapy
Interventions: OTHER: pemetrexed-related hematological toxicity
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: 2R2: Higher Dose Rifampin for 2 Months vs Standard Dose Rifampin for Latent TB.
Status: ACTIVE_NOT_RECRUITING
Conditions: Latent Tuberculosis
Interventions: DRUG: Rifampin double dose|DRUG: Rifampin triple dose|DRUG: Rifampin standard dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bridging Gaps in the Neuroimaging Puzzle: New Ways to Image Brain Anatomy and Function in Health and Disease Using Electroencephalography and 7 Tesla Magnetic Resonance Imaging
Status: RECRUITING
Conditions: Healthy|Epilepsy|Psychosis|Essential Tremor
Interventions: DEVICE: Simultaneous EEG-fMRI at 7 Tesla|DEVICE: Structural MRI at 7 Tesla
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phase II Study Using CHFR Methylation Status in Patients With Metastatic Esophageal, Gastroesophageal, Gastric Cancer.
Status: COMPLETED
Conditions: Metastatic Esophageal Cancer|Gastroesophageal Cancer|Gastric Cancer
Interventions: DRUG: Docetaxel|DRUG: Leucovorin|DRUG: Fluorouracil|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HEALTH4CLL2: A Randomized Waitlist Control Trial of Behavioral Interventions in Patients With Chronic Lymphocytic Leukemia
Status: RECRUITING
Conditions: Chronic Lymphocytic Leukemia
Interventions: BEHAVIORAL: Questionnaires|OTHER: Fit Bit
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Randomized Trial of Coartemether and Artekin for the Treatment of Uncomplicated Malaria in Papua, Indonesia.
Status: COMPLETED
Conditions: Falciparum Malaria|Vivax Malaria
Interventions: DRUG: Artekin / Coartemther
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Future Thinking to Improve Parent-Child Relationships
Status: ENROLLING_BY_INVITATION
Conditions: Behavior, Health
Interventions: BEHAVIORAL: Episodic Future Thinking (EFT)|BEHAVIORAL: Episodic Recent Thinking (ERT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Pilot Study of Nivolumab w/Ipilimumab or Relatlimab in Surgically Resectable Melanoma Brain Metastases
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Melanoma|Metastasis to Brain
Interventions: DRUG: Nivolumab|DRUG: Ipilimumab|DRUG: Nivolumab + Relatlimab|PROCEDURE: Standard of Care Craniotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ankaferd Blood Stopper for Hemostasis After Transradial Coronary Angiography
Status: UNKNOWN
Conditions: Radial Artery Injury|Hematoma|Bleed
Interventions: OTHER: ABS|DEVICE: TR Band|OTHER: CS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Serological Response to Antipneumococcal Vaccination and Impact on Streptococcus Pneumoniae Nasal Carriage in HIV Adults
Status: COMPLETED
Conditions: HIV Infection|Pneumococcal Infections
Interventions: BIOLOGICAL: pneumococcal conjugate 13 valent vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: BrUOG 295: Adjuvant FOLFOX-A For Resected Pancreatic Cancer: A Phase II Brown University Oncology Research Group Trial
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DRUG: FOLFOXA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pegylated Recombinant Human Arginase 1 in Combination With Oxaliplatin and Capecitabine for the Treatment of HCC
Status: COMPLETED
Conditions: Hepatocellular Carcinoma
Interventions: BIOLOGICAL: PACOX
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Changes After Angiotensin Converting Enzyme (ACE) Inhibitor Replacement by Angiotensin II Receptor Type I (AT1) Blocker
Status: UNKNOWN
Conditions: Hypertension
Interventions: DRUG: Candesartan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Brief Internet-delivered Intervention for Children and Adolescents With Anxiety and Depression Symptoms
Status: COMPLETED
Conditions: Childhood Anxiety Disorder|Childhood Depression
Interventions: BEHAVIORAL: Telepsychotherapy|BEHAVIORAL: Psychoeducational Videos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess Safety and Target Engagement of E2814 in Participants With Mild to Moderate Cognitive Impairment Due to Dominantly Inherited Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer Disease
Interventions: DRUG: E2814
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Topical Budesonide Treatment for Eosinophilic Esophagitis (EoE)
Status: COMPLETED
Conditions: Eosinophilic Esophagitis
Interventions: DRUG: inhaled/swallowed budesonide|DRUG: viscous/swallowed budesonide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, Pharmacokinetics(PK), Pharmacodynamics(PD) and Food Effect of HRS9950 in Healthy and CHB Subjects
Status: UNKNOWN
Conditions: Chronic Hepatitis b
Interventions: DRUG: HRS9950|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Glycemic Response to Wild Rice and Wild Rice Blends in Humans Study
Status: COMPLETED
Conditions: Blood Glucose
Interventions: OTHER: Whole white rice (control)|OTHER: Whole brown rice|OTHER: Whole wild rice|OTHER: 15% Wild rice and 85% Brown rice blend - Stovetop|OTHER: 15% Wild rice and 85% Brown rice blend - Microwaved
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Low QRS Voltages in Young Healthy Individuals and Athletes
Status: RECRUITING
Conditions: Sudden Cardiac Death|Sudden Cardiac Arrest|Sudden Cardiac Death Due to Cardiac Arrhythmia|Arrhythmogenic Right Ventricular Cardiomyopathy|Arrhythmogenic Left Ventricular Cardiomyopathy|Dilated Cardiomyopathy
Interventions: DIAGNOSTIC_TEST: Cardiovascular magnetic resonance scan - 3T scanner (Siemens Vida)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase 1b/2 Safety and Tolerability Study of MEDI6469 in Combination With Therapeutic Immune Agents or Monoclonal Antibodies
Status: TERMINATED
Conditions: Advanced Solid Tumors|Aggressive B-cell Lymphomas
Interventions: BIOLOGICAL: MEDI6469 Monotherapy|BIOLOGICAL: MEDI6469 Plus Tremelimumab|BIOLOGICAL: MEDI6469 Plus Durvalumab|BIOLOGICAL: MEDI6469 plus Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vitamin B6 and Depression in Pregnant and Peri-partum Women
Status: RECRUITING
Conditions: Postpartum Depression|Heart Rate Variability
Interventions: COMBINATION_PRODUCT: Vitamin B6|COMBINATION_PRODUCT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Enhancing Graft vs Leukemia Via Delayed Ex-Vivo Co-Stimulated DLI After Non-Myeloablative Stem Cell Transplantation
Status: COMPLETED
Conditions: Acute Myelogenous Leukemia|Acute Lymphoblastic Leukemia|Myelodysplastic Syndrome
Interventions: DRUG: Non-myeloablative allogeneic stem cell transplant with prophylactic activated DLI|DRUG: "Prophylactic" delayed ADLI|DRUG: "Prophylactic" delayed activated donor lymphocyte infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Human Repeated Insult Patch Test (HRIPT) of Azelaic Acid Pre Foam Formulation
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: azelaic acid pre foam formulation|DRUG: Vehicle pre foam formulation|DRUG: Water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Cadisegliatin as Adjunctive Therapy in Type 1 Diabetes
Status: SUSPENDED
Conditions: Diabetes Mellitus, Type 1
Interventions: DRUG: Cadisegliatin 800 mg QD|DRUG: Cadisegliatin 800 mg BID|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Superior Hypogastric Nerve Plexus Block With Bupivacaine After Robotic Resection of Endometriosis
Status: RECRUITING
Conditions: Endometriosis
Interventions: DRUG: Bupivacaine Hydrochloride|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Comparative Effect of Active Release Technique Versus Self-myofascial Release in Improving Piriformis Syndrome
Status: COMPLETED
Conditions: Piriformis Syndrome
Interventions: OTHER: Active release technique|OTHER: Self-myofascial release
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: MIVetsCan: Cannabidiol (CBD)-Care Trial
Status: RECRUITING
Conditions: Pain, Chronic
Interventions: DRUG: Placebo|DRUG: Cannabidiol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Endostomal Three-dimensional Ultrasonography for Parastomal Hernia
Status: UNKNOWN
Conditions: Parastomal Hernia
Interventions: DIAGNOSTIC_TEST: Endostomal three-dimensional ultrasonography|DIAGNOSTIC_TEST: Computerized tomography of the abdomen|DIAGNOSTIC_TEST: Clinical examination|DIAGNOSTIC_TEST: Evaluation at laparotomy/laparoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Sorrel 25R Injector - Sorrel Clinical Study Protocol
Status: UNKNOWN
Conditions: Injection Site|Injection Site Reaction|Injection Site Irritation
Interventions: DEVICE: Sorrel Wearable Injector
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Safety and Efficacy Study of Alefacept in the Treatment of Moderate to Severe Erosive Mucosal Lichen Planus
Status: TERMINATED
Conditions: Lichen Planus
Interventions: DRUG: Amevive (Alefacept)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Soy Isoflavones on Non-alcoholic Fatty Liver Disease and the Level of FGF-21 and Fetuin A
Status: COMPLETED
Conditions: NAFLD
Interventions: DIETARY_SUPPLEMENT: Soy isoflavone|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phytoestrogen, NO Donors, N-acetyl Cysteine Add Therapy to Clomiphene Citrate to Improve Pregnancy Rate in PCO Patients
Status: UNKNOWN
Conditions: Infertility
Interventions: DRUG: Phytoestrogens, Isosorbid mononitrate, N-acetyl cysteine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Alternative Treatments for Premenstrual Dysphoric Disorder
Status: COMPLETED
Conditions: Premenstrual Dysphoric Disorder
Interventions: OTHER: LWT+AM BWL|OTHER: EWT+PM BWL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Arthritis Foundation Exercise Program & "10 Keys" to Healthy Aging--Prevention Research Center
Status: COMPLETED
Conditions: Arthritis|Diabetes|Hypertension|Preventive Behaviors
Interventions: BEHAVIORAL: AFEP|BEHAVIORAL: "10 Keys" to Healthy Aging
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Short Term Omega-3 Supplementation on Performance
Status: COMPLETED
Conditions: Muscle Fatigue|Muscle Strength
Interventions: DIETARY_SUPPLEMENT: Omega-3|DIETARY_SUPPLEMENT: Olive oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: The Effect of Anesthetic Technique on VEGF-C and PGE2
Status: COMPLETED
Conditions: Uterine Leiomyomas
Interventions: OTHER: general anesthesia and patient controlled intravenous analgesia|OTHER: spinal anesthesia and continuous postoperative epidural analgesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Study in Healthy Adult Subjects to Assess the Effect of Phosphate Binders on the Pharmacokinetics of a Single Dose of Vadadustat
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Vadadustat|DRUG: Sevelamer carbonate|DRUG: Calcium acetate|DRUG: Auryxia®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pegylated Interferon Alfa-2b Plus Ribavirin in Chronic Hepatitis B and Delta
Status: UNKNOWN
Conditions: Chronic Hepatitis B|Chronic Hepatitis D
Interventions: DRUG: pegylated IFN alfa-2b plus ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: FOLFIRINOX + RT for Pancreatic Cancer
Status: UNKNOWN
Conditions: Pancreatic Cancer
Interventions: DRUG: FOLFIRINOX|DRUG: Capecitabine|RADIATION: Short Course Radiation|PROCEDURE: Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of the Combination of Isosorbide Dinitrate Spray and Chitosan in Diabetic Foot Ulcers
Status: COMPLETED
Conditions: Diabetic Foot Ulcers
Interventions: DRUG: Chitosan|DRUG: Isosorbide dinitrate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Screening For Asymptomatic Obstructive Coronary Artery Disease Among High-Risk Diabetic Patients Using CT Angiography, Following Core 64
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: PROCEDURE: CT Angiography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparison of Venlafaxine and Fluoxetine in the Treatment of Postmenopausal Women With Major Depression
Status: COMPLETED
Conditions: Major Depression
Interventions: DRUG: venlafaxine|DRUG: fluoxetine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Stereotactic Body Radiation Therapy for Spinal Metastases in Favorite Tumors
Status: RECRUITING
Conditions: Breast Cancer|Prostate Cancer|Non Small Cell Lung Cancer
Interventions: RADIATION: Stereotactic Body Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 2a Study of HU6 in Subjects With Elevated Liver Fat and High BMI Volunteers
Status: COMPLETED
Conditions: NASH - Nonalcoholic Steatohepatitis
Interventions: DRUG: HU6|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Intravenous OAV101 (AVXS-101) in Pediatric Patients With Spinal Muscular Atrophy (SMA) (OFELIA)
Status: COMPLETED
Conditions: Muscular Atrophy, Spinal
Interventions: GENETIC: OAV101
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HIV Self Testing of Male Partners of Women in PMTCT
Status: COMPLETED
Conditions: ART Adherence|PMTCT|Linkage to Care|HIV|PrEP
Interventions: BEHAVIORAL: HIV self-test kit|BEHAVIORAL: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Clinical Efficacy of Acupuncture as an Adjunct to Methadone Treatment Services for Heroin Addicts
Status: COMPLETED
Conditions: Opiate Dependence
Interventions: PROCEDURE: Ture acupuncture|PROCEDURE: Sham acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Bioavailability of Two Doses of cogniVida™ With One Dose of Rebaudioside A in Healthy Male Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: cogniVida 50mg/day|DIETARY_SUPPLEMENT: cogniVida100mg/day|DIETARY_SUPPLEMENT: Rebaudioside-A 303.7mg/day
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Single Ascending Dose Study of GZ402668 in Patients With Progressive Multiple Sclerosis
Status: COMPLETED
Conditions: Progressive Multiple Sclerosis
Interventions: DRUG: GZ402668|DRUG: Placebo|DRUG: Acyclovir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of ALGRX 4975 in the Treatment of Postoperative Pain After Gall Bladder Removal
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: ALGRX 4975
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Study of ALKS 5461 for the Treatment of Major Depressive Disorder (MDD) - the FORWARD-4 Study
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: High Dose ALKS 5461|DRUG: Low Dose ALKS 5461|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of a Dietary Supplement in Breastfeeding Mothers (WellFed)
Status: RECRUITING
Conditions: Dietary Habits|Dietary Supplements|Maternal Health|Breastfeeding|Infant Health
Interventions: DIETARY_SUPPLEMENT: Supplement containing a protein hydrolysate + beta glucan (Wellmune®)|DIETARY_SUPPLEMENT: Placebo supplement containing maltodextron
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Fascia Release Techniques Applied to Plantar Flexor Muscles and Acute Efficacy of Kinesio Taping
Status: COMPLETED
Conditions: Balance; Distorted|Fascia; Anomaly
Interventions: OTHER: taping|OTHER: massage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Efficacy of Everolimus With Lower Versus Higher Levels of Tacrolimus in de Novo Renal Transplant Patients
Status: COMPLETED
Conditions: Renal Transplantation
Interventions: DRUG: Everolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Impact of Immunoscore Colon Test on Adjuvant Therapeutic Strategy in Non-Metastatic Colon Cancer
Status: WITHDRAWN
Conditions: Colonic Neoplasms
Interventions: DIAGNOSTIC_TEST: Immunoscore Colon Test
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety Study to Assess the FEasibility of Use of the TRYTON Bifurcation Coronary Stent System (SAFE-TRY)
Status: COMPLETED
Conditions: Coronary Artery Disease|Angioplasty, Transluminal, Percutaneous Coronary
Interventions: DEVICE: Tryton
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Visualizing Vascular Mechanisms of Salt Sensitivity
Status: COMPLETED
Conditions: Obesity|Cardiovascular Risk Factor|Salt; Excess
Interventions: DIETARY_SUPPLEMENT: Low-salt diet|DIETARY_SUPPLEMENT: High-salt diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of LEGALON SIL on Hepatitis C Virus Recurrence in Stable Liver Transplanted Patients
Status: TERMINATED
Conditions: Hepatitis C Virus Recurrence
Interventions: DRUG: Silibinin (Legalon-SIL)|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: FNA Guided Ultrasonography Needle Technique Axial Vs Lateral Approach Study
Status: UNKNOWN
Conditions: Thyroid Nodule
Interventions: PROCEDURE: long axis FNA method
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: The Impact of a School-Based, Trauma-Informed CBT Intervention for Young Women
Status: COMPLETED
Conditions: Anxiety|Anxiety Disorders|Behavioral Symptoms|Depression|Mental Disorders|Stress Disorders, Post-Traumatic|Stress Disorders, Traumatic|Trauma and Stressor Related Disorders|Wounds and Injuries
Interventions: BEHAVIORAL: Working on Womanhood (WOW)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Erythritol and Xylitol on Dental Caries Prevention in Children
Status: UNKNOWN
Conditions: Dental Caries
Interventions: DIETARY_SUPPLEMENT: A, erythritol|DIETARY_SUPPLEMENT: xylitol|DIETARY_SUPPLEMENT: C, sorbitol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: rTMS for the Treatment of Primary Progressive Aphasia: A Randomized Controlled Trial
Status: WITHDRAWN
Conditions: Aphasia, Primary Progressive|Repetitive Transcranical Magnetic Stimulation
Interventions: DEVICE: Magstim rTMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Confirm the Efficacy and Safety of Different Dupilumab Dose Regimens in Adults With Atopic Dermatitis (AD)
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: Dupilumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Non-percutaneous Vertebroplasty With Macroporous Calcium Phosphate Cement (MCPC)
Status: COMPLETED
Conditions: Vertebra Trauma
Interventions: PROCEDURE: non percutaneous vertebroplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial Of [S,S]-Reboxetine In Patients With Chronic Painful Diabetic Peripheral Neuropathy.
Status: TERMINATED
Conditions: Diabetic Neuropathies
Interventions: DRUG: Placebo|DRUG: [S,S]-Reboxetine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Symptomatic Study Investigating Degarelix in Patients Suffering From Prostate Cancer
Status: TERMINATED
Conditions: Prostate Cancer
Interventions: DRUG: Degarelix|DRUG: Goserelin|DRUG: Bicalutamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Efficacy and Safety Study of Fluticasone Furoate/Vilanterol (FF/VI) 200/25 Microgram (mcg) , FF/VI 100/25 mcg, and FF 100 mcg in Adults and Adolescents With Persistent Asthma.
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Fluticasone Furoate/ Vilanterol 200/25 mcg|DRUG: Fluticasone Furoate/ Vilanterol 100/25 mcg|DRUG: Fluticasone Furoate 100 mcg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Activity and Education Program on Patients With Chronic Hepatitis C Infection
Status: UNKNOWN
Conditions: Hepatitis C Virus Infection, Response to Therapy of
Interventions: BEHAVIORAL: Personalized Physical Activity and Psycho-Education (PPAPE) Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Immunogenicity Study of Group B Meningococcal Vaccine to Prevent Meningitis.
Status: COMPLETED
Conditions: Meningitis, Meningococcal, Serogroup B
Interventions: BIOLOGICAL: 25ug Group B Meningococcal 44/76 MOS NOMV 5D Vaccine|BIOLOGICAL: 50ug Group B Meningococcal 44/76 MOS NOMV 5D Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Two-in-one Covered and Uncovered Metal Stent
Status: UNKNOWN
Conditions: Extrahepatic Bile Duct Cancer|Pancreatic Cancer|Lymph Node Metastases|Gallbladder Cancer
Interventions: DEVICE: Two-in-one stent
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acceptability Research on Integrated Point of Care Sexually Transmitted Infection (STI) Testing and Expedited Partner Therapy (EPT)
Status: ACTIVE_NOT_RECRUITING
Conditions: Neisseria Gonorrhea|Trichomoniasis Vaginalis|Chlamydia Trachomatis Infection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Intensive Systolic Blood Pressure Lowering Treatment on Out-of-office Blood Pressure - an Ancillary Study to Effects of Intensive Systolic Blood Pressure Lowering Treatment in Reducing RIsk of Vascular evenTs (ESPRIT) Study
Status: UNKNOWN
Conditions: Blood Pressure
Interventions: DRUG: Intensive BP Arm|DRUG: Standard BP Arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Small Cell Lung Carcinoma Trial With Nivolumab and IpiliMUmab in LImited Disease
Status: UNKNOWN
Conditions: Limited Stage Small Cell Lung Cancer|Small Cell Lung Cancer
Interventions: DRUG: Ipilimumab|DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of H2-BP Electronic Sphygmomanometer
Status: RECRUITING
Conditions: Low Blood Pressure|Normal Blood Pressure|Prehypertension|Hypertension
Interventions: DEVICE: H2-BP
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Early Oral Feeding Versus Traditional Delayed Oral Feeding Post-perforated Peptic Ulcer Repair
Status: RECRUITING
Conditions: Peptic Ulcer Perforation
Interventions: OTHER: Post operative early oral feeding|OTHER: Traditional delayed oral Feeding Post-perforated Peptic Ulcer Repairs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of Fish-oil on Non-alcoholic Steatohepatitis (NASH)
Status: COMPLETED
Conditions: Non-alcoholic Fatty Liver Disease|Non-alcoholic Steatohepatitis
Interventions: OTHER: Omega-3 capsules-Fish Oil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Regorafenib in Combination With Multimodal Metronomic Chemotherapy for Chemo-resistant Metastatic Colorectal Cancers
Status: NOT_YET_RECRUITING
Conditions: Metastatic Colorectal Cancer
Interventions: PROCEDURE: Blood sample|OTHER: Quality of life questionnaires|PROCEDURE: Biopsy|DRUG: Regorafenib|COMBINATION_PRODUCT: Regorafenib + metronomic chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Trastuzumab Emtansine in Participants With Human Epidermal Growth Factor Receptor (HER)2 Immunohistochemistry (IHC)-Positive, Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: Trastuzumab Emtansine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Inspiratory Muscle Training in Sarcoidosis
Status: COMPLETED
Conditions: Sarcoidosis
Interventions: DEVICE: Inspiratory muscle training|DEVICE: Sham inspiratory muscle training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy and Safety of Prophylactic Treatment for Pneumocystis Jirovecii Pneumonia in Patients With Autoimmune Inflammatory Rheumatic Disease
Status: RECRUITING
Conditions: Pneumonia, Pneumocystis|Autoimmune Inflammatory Rheumatic Disease|Autoimmune Diseases|Connective Tissue Disease|Prevention
Interventions: DRUG: Trimethoprim/Sulfamethoxazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of AIN457 on Ozone-induced Airway Neutrophilia Compared to Placebo and Corticosteroid in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: BIOLOGICAL: AIN457|OTHER: Placebo|DRUG: prednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: ALI Post Radiation Therapy in Patients With Lung and Esophageal Canter
Status: ACTIVE_NOT_RECRUITING
Conditions: Solid Tumor Malignancies
Interventions: PROCEDURE: Autologous lymphocyte infusion (ALI)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Safety, Tolerability, Pharmacokinetics and Safety of BG00010 (Neublastin) in Subjects With Sciatica.
Status: COMPLETED
Conditions: Sciatica
Interventions: DRUG: BG00010 (Neublastin)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Engaging Seronegative Youth to Optimize HIV Prevention Continuum
Status: COMPLETED
Conditions: HIV|Mental Health|Substance Use|STI
Interventions: BEHAVIORAL: Automated Messaging & Monitoring|BEHAVIORAL: Peer Support|BEHAVIORAL: Coaching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Computational Cranial and Cervical Muscle Network in Normal and Disordered Voice
Status: ENROLLING_BY_INVITATION
Conditions: Dysphonia
Interventions: DIAGNOSTIC_TEST: surface electromyogram (sEMG)|DIAGNOSTIC_TEST: flexible laryngoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Home-based Physical Activity Programme for Patients With Advanced Interstitial Lung Diseases (iLiFE)
Status: COMPLETED
Conditions: Interstitial Lung Diseases (ILD)
Interventions: OTHER: Home-based physical activity programme|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized Study to Evaluate the Effect of Reminder Notifications and Motivational/Adaptive Messaging on Treatment Adherence
Status: TERMINATED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: COMBINATION_PRODUCT: Concept2 inhaler|COMBINATION_PRODUCT: Concept2 inhaler with patient application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY