pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Study to Evaluate the Safety and Efficacy of E/C/F/TAF Versus E/C/F/TDF in HIV-1 Positive, Antiretroviral Treatment-Naive Adults
Status: COMPLETED
Conditions: HIV|HIV Infections
Interventions: DRUG: E/C/F/TAF|DRUG: E/C/F/TDF|DRUG: E/C/F/TDF Placebo|DRUG: E/C/F/TAF Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Sorafenib, Gemcitabine, and Cisplatin in Advanced Hepatocellular Carcinoma (HCC)
Status: WITHDRAWN
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Gemcitabine / Cisplatin / Sorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Premixed Nitrous Oxide and Oxygen in Patient With Out-of-hospital Moderate Acute Pain
Status: COMPLETED
Conditions: Acute Pain
Interventions: DRUG: Premixed 50% nitrous oxide and oxygen (Kalinox)|DRUG: medical air
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Remimazolam for Postoperative Atrial Fibrillation
Status: RECRUITING
Conditions: Coronary Artery Bypass Grafting|Remimazolam
Interventions: DRUG: Remimazolam|DRUG: midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Adjuvant Adenoidectomy for the Treatment of Chronic OME in Children
Status: NOT_YET_RECRUITING
Conditions: Otitis Media With Effusion in Children
Interventions: PROCEDURE: tympanostomy tube placement|PROCEDURE: adenoidectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dymista Allergen Chamber - Onset of Action Study
Status: COMPLETED
Conditions: Seasonal Allergic Rhinitis
Interventions: DRUG: Treatment A (Dymista): Fixed drug combination of azelastine hydrochloride and fluticasone propionate nasal spray at Visit 3|DRUG: Treatment B (Placebo): Nasal spray with no active dose (Dymista vehicle) at Visit 5|DRUG: Treatment A (Dymista): Fixed drug combination of azelastine hydrochloride and fluticasone propionate nasal spray at Visit 5|DRUG: Treatment B (Placebo): Nasal spray with no active dose (Dymista vehicle) at Visit 3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Preliminary Efficacy Study of an Anti-inflammatory Therapeutic Antibody in Reducing Restenosis.
Status: COMPLETED
Conditions: Patients Undergoing Repeat Peripheral Artery Revascularization
Interventions: DRUG: CV-18C3|PROCEDURE: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lurasidone HCl - A Long Term Safety Phase 3 Study of Patients With Clinically Stable Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder
Interventions: DRUG: Lurasidone HCl|DRUG: Risperidone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safe Passages: Ensuring Quality Transitions From NICU (Neonatal Intensive Care Unit) to Ambulatory Care
Status: COMPLETED
Conditions: Infant, Premature, Diseases
Interventions: BEHAVIORAL: Enhanced Discharge process
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Phototherapeutic Keratectomy (PTK) With Mitomycin in Adenoviral Opacities
Status: UNKNOWN
Conditions: Keratitis|Corneal Opacity
Interventions: PROCEDURE: PTK with mitomycin in Adenoviral Opacities
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vitrectomy and Scleral Shortening for Macular Hole Retinal Detachment or Myopic Traction Maculopathy
Status: COMPLETED
Conditions: Macular Hole Retinal Detachment|Myopic Traction Maculopathy
Interventions: PROCEDURE: Vitrectomy with scleral shortening
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Fibrinogen and Bleeding After Cardiac Surgery
Status: COMPLETED
Conditions: Complications|Bleeding|Coronary Artery Disease
Interventions: DRUG: Fibrinogen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Enhancing Use of Hydroxyurea In Sickle Cell Disease Using Patient Navigators
Status: COMPLETED
Conditions: Sickle Cell Disease
Interventions: BEHAVIORAL: Patient Navigator|BEHAVIORAL: Recruitment into Specialty Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effects of LDX on Functioning of College Students With ADHD
Status: COMPLETED
Conditions: Attention-deficit/Hyperactivity Disorder
Interventions: DRUG: lisdexamfetamine dimesylate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: From the Emergency Department Directly to Ablation of Atrial Fibrillation Study
Status: RECRUITING
Conditions: Atrial Fibrillation (AF)
Interventions: PROCEDURE: Ablation of atrial fibrillation (AF)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multicenter Trial With PegLiposomal Doxorubicin and Carboplatin Combination Chemotherapy in Gynecological Sarcomas and Mixed Epithelial-Mesenchymal Tumors
Status: COMPLETED
Conditions: Mesenchymal Tumor|Carcinosarcoma|Leiomyosarcoma
Interventions: DRUG: PegLiposomal Doxorubicin|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Informative Letters on the Prescription and Receipt of Opioids
Status: WITHDRAWN
Conditions: Economics|Fraud|Delivery of Health Care|Health Expenditures|Prescribing|Centers for Medicare and Medicaid Services (U.S.)
Interventions: OTHER: Patient Consequences Letter|OTHER: Prescriber Consequences Letter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Efficacy of Gevokizumab in the Treatment of Patients With Behçet's Disease Uveitis (EYEGUARD™-B)
Status: TERMINATED
Conditions: Behcet's Uveitis
Interventions: DRUG: Gevokizumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Impact of Virtual Reality Exposure Therapy on Epilepsy/Seizure-Specific Interictal Anxiety
Status: NOT_YET_RECRUITING
Conditions: Epilepsy|Anxiety Disorders
Interventions: DEVICE: HMD: Virtual Reality Exposure Therapy|DEVICE: HMD: Neutral Game
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Outcome Study Assessing a 75 Milligrams (mg) Dose of Macitentan in Patients With Pulmonary Arterial Hypertension
Status: ACTIVE_NOT_RECRUITING
Conditions: Pulmonary Arterial Hypertension
Interventions: DRUG: Macitentan 10 mg|DRUG: Macitentan 37.5 mg|DRUG: Macitentan 75 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Gamification With Escape-Room for Arrhythmia Identification in Critical Patients
Status: RECRUITING
Conditions: Arrythmia|Health Education|Escape-Room
Interventions: BEHAVIORAL: In-person Escape Room|BEHAVIORAL: Virtual Escape-Room
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Voluntary HIV Counseling, Testing, and Medication for Pregnant Women to Prevent Mother-to-Child HIV Transmission
Status: COMPLETED
Conditions: HIV Infections
Interventions: PROCEDURE: Intrapartum HIV counseling/testing|PROCEDURE: Postpartum HIV counseling/testing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparison Between Two Different Tissue-Level Implant Systems: A Prospective Clinical Study
Status: COMPLETED
Conditions: Peri-implant Bone Loss|Implant Stability|Vertical Soft Tissue Thickness
Interventions: OTHER: Straumann Standard Plus implant and JDental care (JD) Octa implant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Erector Spinal Plane Block (ESPB) for Analgesia in Laparoscopic Cholecystectomy
Status: UNKNOWN
Conditions: Analgesia
Interventions: PROCEDURE: Erector spinal plane block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Use of Low Molecular Weight Heparin in Hemodiafiltration
Status: COMPLETED
Conditions: Chronic Kidney Disease
Interventions: PROCEDURE: At start of the session, at the inlet line|PROCEDURE: 5 minutes after the start of the session, at the inlet line|PROCEDURE: At the start of the session, at the outlet line
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of GRN163L With Paclitaxel and Carboplatin in Patients With Advanced or Metastatic Non Small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DRUG: Imetelstat Sodium (GRN163L)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Macular Pigment Density Evolution in Unilateral Wet AMD Versus Non AMD Patients With or Without Lutein and Zeaxanthine Supplementation
Status: COMPLETED
Conditions: Exudative Age-related Macular Degeneration
Interventions: DIETARY_SUPPLEMENT: Nutrof Total|DIETARY_SUPPLEMENT: food supplement without Lutein and Zeaxanthin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: An Integrated Nutrition Intervention to Promote Healthy Eating Habits for Children With ASD
Status: ACTIVE_NOT_RECRUITING
Conditions: Autism Spectrum Disorder
Interventions: BEHAVIORAL: Autism Eats nutrition intervention|BEHAVIORAL: We Can! enhanced usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Phase I Trial of the Selective Inhibitor of Nuclear Export, KPT-330, in Relapsed Childhood ALL and AML
Status: ACTIVE_NOT_RECRUITING
Conditions: Relapsed Acute Lymphoblastic Leukemia (ALL)|Refractory Acute Lymphoblastic Leukemia (ALL)|Relapsed Acute Myelogenous Leukemia (AML)|Refractory Acute Myelogenous Leukemia (AML)|Relapsed Mixed Lineage Leukemia|Refractory Mixed Lineage Leukemia|Relapsed Biphenotypic Leukemia|Refractory Biphenotypic Leukemia|Chronic Myelogenous Leukemia (CML) in Blast Crisis
Interventions: DRUG: KPT-330
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ventriculomegaly and Gait Disturbance in the Senior Population in the Region of Västerbotten
Status: COMPLETED
Conditions: Idiopathic Normal Pressure Hydrocephalus (INPH)|Brain Diseases|Central Nervous System Diseases|Dementia|Gait Disorders, Neurologic|Hydrocephalus, Normal Pressure
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Feasibility & Acceptability of App-based Cognitive Behavioral Therapy for Postpartum Depression Prevention
Status: RECRUITING
Conditions: Postpartum Depression|Postpartum Anxiety|Stress
Interventions: BEHAVIORAL: M.Bapp|BEHAVIORAL: App-based parenting education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of PF-06410293 Following Subcutaneous Administration Using A Prefilled Syringe Or A Prefilled Pen In Healthy Adult Subjects
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DEVICE: PF-06410293 PFS|DEVICE: PF-06410293 PFP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: High Dose Chemotherapy, Peripheral Stem Cell Transplantation, and Interleukin-2 in Treating Patients With Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Leukemia
Interventions: BIOLOGICAL: aldesleukin|BIOLOGICAL: filgrastim|DRUG: cyclophosphamide|DRUG: cytarabine|DRUG: etoposide|DRUG: idarubicin|DRUG: melphalan|PROCEDURE: peripheral blood stem cell transplantation|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Platelet-rich Fibrin on Rotator Cuff Repair
Status: COMPLETED
Conditions: Rotator Cuff Tears of the Shoulder
Interventions: PROCEDURE: Arthroscopic repair without platelet rich fibrin|BIOLOGICAL: PRF (vivostat ®) administration after rotator cuff repair
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Telemedicine-based, Multidisciplinary-team, Intervention to Reduce Unnecessary Hospitalizations
Status: COMPLETED
Conditions: Dementia Alzheimers|Disruptive Behavior
Interventions: BEHAVIORAL: Behavioral modification and education on pharmacologic treatments.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: |Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Evaluate the Combination of Valsartan and Amlodipine in Hypertensive Patients Not Controlled on Monotherapy
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: valsartan|DRUG: hydrochlorothiazide|DRUG: amlodipine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: EUS-FNB vs. Single-incision Needle-knife (SINK) Biopsy for Gastrointestinal SELs
Status: UNKNOWN
Conditions: Disorder of Upper Gastrointestinal Tract|Gastrointestinal Stromal Tumors|Gastrointestinal Neoplasms
Interventions: PROCEDURE: EUS-guided fine needle biopsy|PROCEDURE: Single incision needle knife biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Pharmacokinetics, Pharmacodynamics, and Impact of Inorganic Nitrate on Exercise in HFpEF
Status: COMPLETED
Conditions: Heart Failure|Diastolic Heart Failure
Interventions: DRUG: KNO3|DRUG: KCl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Role of Circadian Clock Proteins in Innate and Adaptive Immunity
Status: RECRUITING
Conditions: Pneumonia|Necrotizing Soft Tissue Infection|Intraabdominal Infections|Infection Joint
Interventions: OTHER: Blue Light
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Quality of Life With Nutritional Supplementation in Patients With Locally Advanced/Metastatic Pancreatic Cancer.
Status: WITHDRAWN
Conditions: Quality of Life|Locally Advanced Pancreatic Carcinoma|Metastatic Pancreatic Cancer
Interventions: DIETARY_SUPPLEMENT: ARACOMPLEX®|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Repurposing Metformin as a Leukemia-preventive Drug in CCUS and LR-MDS
Status: RECRUITING
Conditions: Preleukemia|Myelodysplastic Neoplasm|Cytopenia|Preleukemic Anemia
Interventions: DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Research Study Looking at How the Use of NovoPen® 6 for Treatment With Tresiba® & Fiasp® Affects the Blood Sugar Level in Patients With Type 1 Diabetes as Part of Local Clinical Practice
Status: ENROLLING_BY_INVITATION
Conditions: Diabetes Mellitus, Type 1
Interventions: DRUG: Insulin degludec|DRUG: Fast-acting insulin aspart
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: GLP-1's Effect on Cardiac Parameters and Mesenteric Blood Flow
Status: UNKNOWN
Conditions: Healthy
Interventions: OTHER: 1,5 nmol/kg,GLP-1 sc injection|OTHER: 1,5 nmol/kg GLP-1 9-36amide, sc injection|OTHER: Exendin-4 ;10 ug,sc injection|OTHER: saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Dupilumab in Eosinophilic Gastritis
Status: ACTIVE_NOT_RECRUITING
Conditions: Eosinophilic Gastritis|Eosinophilic Gastroenteritis
Interventions: DRUG: Dupilumab (blinded)|DRUG: Placebo (blinded)|DRUG: Dupilumab (open-label)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: SPLATT to Peroneus Brevis vs TATT to Lateral Cuneiform
Status: ENROLLING_BY_INVITATION
Conditions: Recurrent Congenital Talipes Equinovarus
Interventions: PROCEDURE: SPLATT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Comparing a Virtual vs. Face to Face Weight Management Program Using Phentermine for Patients With Overweight or Obesity
Status: COMPLETED
Conditions: Obesity
Interventions: DRUG: Phentermine 37.5 Mg|BEHAVIORAL: Dietary program|BEHAVIORAL: Exercise program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Interventions to Curb Hepatitis C Reinfections Among Men Who Have Sex With Men
Status: ACTIVE_NOT_RECRUITING
Conditions: Hepatitis C Virus Infection
Interventions: BEHAVIORAL: Behavioural intervention|DIAGNOSTIC_TEST: HCV RNA home-based test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Strict Blood Pressure Control and ACE-Inhibition on Progression of Chronic Renal Failure in Pediatric Patients
Status: COMPLETED
Conditions: Children|Chronic Renal Failure|Hypertension|Acquired Kidney Disease|Congenital Kidney Disease
Interventions: DRUG: ACE Inhibition|DRUG: Intensified Blood Pressure Control|DRUG: Add-on Angiotensin Receptor Blockade
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Nitazoxanide in the Treatment of Acute Uncomplicated Influenza
Status: COMPLETED
Conditions: Influenza
Interventions: DRUG: Nitazoxanide|DRUG: Oseltamivir|DRUG: Placebo Oral Tablet|DRUG: Placebo Oral Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Web-based Home Multimodal Prehabilitation for Patients Undergoing Major Surgeries
Status: NOT_YET_RECRUITING
Conditions: Perioperative Recovery, Prehabilitation
Interventions: BEHAVIORAL: Prehabilitation group
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: LUDEC Study - Pilot Study of the Lavage of the Uterine Cavity for the Diagnosis of Endometrial Carcinoma
Status: COMPLETED
Conditions: Cancer of Endometrium|Carcinoma of Endometrium|Endometrial Neoplasms
Interventions: PROCEDURE: Lavage of the Uterus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Imatinib and Carvedilol for High Blood Pressure in the Lungs in Adults With Sickle Cell Disease
Status: WITHDRAWN
Conditions: Pulmonary Hypertension
Interventions: DRUG: Carvedilol|DRUG: Imatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Educational Program to Improve Heart Failure Outcomes in Adults Living in Rural Areas
Status: COMPLETED
Conditions: Heart Failure, Congestive
Interventions: BEHAVIORAL: Fluid Watchers LITE Educational Intervention|BEHAVIORAL: Fluid Watchers PLUS Educational Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: An Electronic Data Capture Study to Assess the Long-term Performance of the DePuy PROXIMA™ Hip in Primary Total Hip Replacement
Status: TERMINATED
Conditions: Rheumatoid Arthritis|Osteoarthritis|Post-traumatic Arthritis|Avascular Necrosis|Traumatic Femoral Fractures|Congenital Hip Dysplasia
Interventions: DEVICE: DePuy Proxima™ Hip
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pathogenesis of the Cardiometabolic Risk in Youth With Type 1 Diabetes
Status: TERMINATED
Conditions: Type 1 Diabetes|De Novo Lipogenesis
Interventions: DIAGNOSTIC_TEST: Oral Glucose Tolerance Test
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Cerebral Microembolism During Hemodialysis
Status: COMPLETED
Conditions: Complication of Dialysis|Thrombus Due to Renal Dialysis Device, Implant, or Graft|Cerebral Embolism
Interventions: DEVICE: Renal hemodialysis (Fresenius 2008K, Bad Homburg, Germany)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: VELVET, a Dose Range Finding Trial of Veltuzumab in Subjects With Moderate to Severe Rheumatoid Arthritis
Status: TERMINATED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Veltuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparative Efficacy Study: Treatment for Non-healing Diabetic Foot Ulcers
Status: TERMINATED
Conditions: Foot Ulcer, Diabetic
Interventions: DEVICE: MatriStem|DEVICE: Cellular Dermal Replacement Tissue
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Representations and Strategies for Recovery
Status: COMPLETED
Conditions: Schizophrenia, Undifferentiated|Anorexia|Bipolar Disorders|Personality Disorders
Interventions: BEHAVIORAL: Collection of the individual narrative, semi-directed interviews
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effects of Metformin in Pre-frail Elderly
Status: UNKNOWN
Conditions: Pre-frail Elderly
Interventions: DRUG: Metformin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Healing Touch in Treating Fatigue in Women Undergoing Radiation Therapy for Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer|Depression|Fatigue
Interventions: PROCEDURE: Bio-field energy therapy|PROCEDURE: fatigue assessment and management|PROCEDURE: psychosocial assessment and care|PROCEDURE: quality-of-life assessment|PROCEDURE: therapeutic touch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Lenalidomide Combined With Vorinostat/Gemcitabine/Busulfan/Melphalan With Autologous Stem-Cell Transplantation in Diffuse Large B-Cell Lymphoma of the ABC Subtype
Status: TERMINATED
Conditions: Lymphoma
Interventions: DRUG: Lenalidomide|DRUG: Vorinostat|DRUG: Gemcitabine|DRUG: Busulfan|DRUG: Melphalan|DRUG: Rituximab|DRUG: Dexamethasone|DRUG: Caphosol|DRUG: Glutamine|DRUG: Pyridoxine|DRUG: Enoxaparin|PROCEDURE: Stem Cell Transplant|DRUG: Palifermin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rivaroxaban for the Prevention of Venous Thromboembolism in Asian Patients With Cancer
Status: COMPLETED
Conditions: Rivaroxaban|Cancer-associated Thrombosis|Recurrence|Bleeding
Interventions: DRUG: Rivaroxaban
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dexamethasone-implant for the Treatment of RVO
Status: COMPLETED
Conditions: Macular Edema Caused by Retinal Vein Occlusion
Interventions: DRUG: Dexamethasone implant|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Extension Study Evaluating the Safety and Efficacy of Subcutaneous Tocilizumab (RoActemra/Actemra) Administration in Systemic and Polyarticular-Course Juvenile Idiopathic Arthritis
Status: COMPLETED
Conditions: Juvenile Idiopathic Arthritis
Interventions: DRUG: Tocilizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long-acting Parasternal Blocks for Analgesia After Cardiac Surgery
Status: COMPLETED
Conditions: Coronary Artery Bypass Graft Surgery
Interventions: DRUG: Parasternal blocks|DRUG: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pilot Study to Clinical Evaluate Lacrima Medical Device in Insomnia Patients
Status: COMPLETED
Conditions: Chronic Insomnia
Interventions: DEVICE: Lacrima Medical Device and sham comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bone Volume Changes After Socket Preservation Using Geistlich Bio-Oss Collagen and Mucograft Seal
Status: COMPLETED
Conditions: Bio-Oss; Mucograft
Interventions: DEVICE: Geistlich Bio-Oss® Collagen and Geistlich Mucograft® Seal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: To Scan or Not to Scan: The Role of Follow-up CT Scanning for Management of Chronic Subdural Hematoma After Neurosurgical Evacuation
Status: COMPLETED
Conditions: Chronic Subdural Hematoma
Interventions: OTHER: cranial CT scan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Intravenous Versus Perineural Dexmedetomidine as Adjuvant in Adductor Canal Block for Total Knee Arthroplasty
Status: COMPLETED
Conditions: Post Spinal Anesthesia Shivering
Interventions: DRUG: intravenous dexmedetomidine|DRUG: adductor canal block dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: 10-Propargyl-10-Deazaaminopterin Plus Probenecid in Treating Patients With Advanced Solid Tumors
Status: COMPLETED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: pralatrexate|DRUG: probenecid
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Effect of Pantoprazole 40mg Daily vs Placebo on Power Spectral Analysis of the Sleep EEG of Patients With GERD.
Status: COMPLETED
Conditions: Gastroesophageal Reflux Disease
Interventions: DRUG: Pantoprazole|DRUG: Pantoprazole|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Oblique-axis and Long-axis Approaches for Axillary Vein Catheterization Under Ultrasound Guidance
Status: RECRUITING
Conditions: Central Venous Catheterization
Interventions: PROCEDURE: Oblique-axis approach group|PROCEDURE: Long-axis approach group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Open-Label Extension Trial to Assess the Long-Term Safety of ZX008 (Fenfluramine Hydrochloride HCl) Oral Solution in Children and Young Adults With Dravet Syndrome
Status: COMPLETED
Conditions: Dravet Syndrome
Interventions: DRUG: ZX008 (Fenfluramine Hydrochloride)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety and Effectiveness of VOLBELLA XC Hyaluronic Acid (HA) Injectable Gel to Correct Infraorbital Hollowing
Status: COMPLETED
Conditions: Infraorbital Hollowing
Interventions: DEVICE: JUVÉDERM VOLBELLA® XC injectable gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MERCI Chronic Pain Research Clinic
Status: RECRUITING
Conditions: Chronic Pain
Interventions: BEHAVIORAL: Behavior Change Coaching|BEHAVIORAL: Nutrition|OTHER: Autonomic Recalibration|PROCEDURE: Dry Needling|OTHER: Osteopathic Manipulative Treatment|BEHAVIORAL: Counseling Psychology|OTHER: Multiple Treatments
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasound Guided Lateral Femoral Cutaneous Block (LFCNB) And Femoral Nerve Block (FNB) For Postoperative Pain Control After Hip Surgery
Status: UNKNOWN
Conditions: -Postoperative Pain
Interventions: PROCEDURE: LFCNB|PROCEDURE: FNB|PROCEDURE: LFCNB|PROCEDURE: FNB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing Effectiveness of Merocel and Packing With Tranexamic Acid in the Management of Anterior Epistaxis
Status: COMPLETED
Conditions: Tranexamic Acid|Epistaxis|Nasal Packing
Interventions: DRUG: Tranexamic Acid|DRUG: Normal saline|DEVICE: Merocel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare Various Root Canal Cleaning Devices Based on Cavitation,Ultrasonic and Conventional Methods.
Status: RECRUITING
Conditions: Apical Periodontitis
Interventions: DEVICE: Passive Ultrasonic Irrigation (PUI) group|DEVICE: Endoclean (EC) group|DEVICE: Conventional group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Optimized Titration and Delivery of Bedtime Insulin on Prevention of Nocturnal Hypoglycemia
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus
Interventions: BEHAVIORAL: Bedtime snacks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Vincristine and Irinotecan With or Without Temozolomide in Children and Adults With Refractory/Relapsed Rhabdomyosarcoma
Status: COMPLETED
Conditions: RHABDOMYOSARCOMA
Interventions: DRUG: Vincristine, Irinotecan|DRUG: Vincristine, Irinotecan, Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Cooling Therapy for Post-Operative Pain in Open Carpal Tunnel Release
Status: NOT_YET_RECRUITING
Conditions: Carpal Tunnel Syndrome|Perioperative/Postoperative Complications
Interventions: OTHER: Polarcare Machine|OTHER: Standard of care ice therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study to Evaluate the Pharmacokinetics, Safety, and Pharmacodynamics of INCB000928 in Participants With Impaired Renal Function and Hemodialysis
Status: COMPLETED
Conditions: Renal Impairment|Hemodialysis
Interventions: DRUG: INCB000928
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antibiotics Treatment of Cholangitis Post-Kasai Portoenterostomy
Status: COMPLETED
Conditions: Cholangitis, Secondary Biliary|Treatment Compliance|Antibodies Drug Specific
Interventions: DRUG: Sulperazon|DRUG: Teicoplanin|DRUG: Meropenem Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lifestyle Intervention for Women With Recent Pre-eclampsia or Gestational Diabetes Mellitus ('Mom's Healthy Heart')
Status: COMPLETED
Conditions: Pre-Eclampsia|Gestational Diabetes
Interventions: BEHAVIORAL: Web-based lifestyle intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: BCI Driving FES and Hand Orthosis for Upper Limb Rehabilitation in Chronic Stroke
Status: RECRUITING
Conditions: Stroke, Cerebrovascular|Hemiplegia and Hemiparesis|Stroke/Brain Attack
Interventions: COMBINATION_PRODUCT: EEG-based brain-computer interface|COMBINATION_PRODUCT: Sham EEG-based brain-computer interface|DEVICE: Functional Electrical Stimulation|DEVICE: Active hand orthosis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Diclofenac Gel in the Treatment of Cervicogenic Headache
Status: RECRUITING
Conditions: Cervicogenic Headache
Interventions: DRUG: Diclofenac 1% Topical|OTHER: Petroleum Jelly
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ESP vs TAP in Total Laparoscopic Hysterectomy
Status: COMPLETED
Conditions: Anesthesia|Gynecologic Cancer
Interventions: PROCEDURE: General anesthesia + TAP block|PROCEDURE: General anesthesia + ESP block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of a Special Modality of Back Muscles Strengthening for Postural Deformations in Parkinsonian Patient
Status: RECRUITING
Conditions: Parkinson Disease|Physical Medicine|Rehabilitation
Interventions: OTHER: Isokinetic reeducation|OTHER: Conventional reeducation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Japanese Bridging Study Conducted in the United States
Status: WITHDRAWN
Conditions: Hepatitis C Virus
Interventions: DRUG: BMS-791325|DRUG: BMS-791325|DRUG: BMS-791325|DRUG: BMS-791325|DRUG: BMS-791325|DRUG: BMS-791325|DRUG: Placebo|DRUG: Placebo|DRUG: Placebo|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Beneficial Effects of Korean Traditional Diets in Subjects With Hypertension and Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DIETARY_SUPPLEMENT: Korean traditional diets|DIETARY_SUPPLEMENT: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Midostaurin Associated With Standard Chemotherapy in Patients With Core-binding Factor Leukemia
Status: RECRUITING
Conditions: Core Binding Factor Acute Myeloid Leukemia (CBF-AML)
Interventions: DRUG: Midostaurin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prophylaxis With Caspofungin in High-Risk Liver Transplantation
Status: UNKNOWN
Conditions: Liver Transplantation|Fungal Infection
Interventions: DRUG: Caspofungin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study to Evaluate The Analgesic Efficacy and Safety of Intravenous Paracetamol in Subjects With Postoperative Pain After Total Hip Arthroplasty
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Paracetamol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Asymptomatic Bacteriuria Guideline Implementation Study
Status: COMPLETED
Conditions: Infection Due to Indwelling Urinary Catheter|Asymptomatic Bacteriuria
Interventions: BEHAVIORAL: Audit-Feedback
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Role of Maintenance Oral Clofarabine in Older Adults With Acute Myeloid Leukemia
Status: WITHDRAWN
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Clofarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Effect AZD4831 in Japanese and Chinese Healthy Volunteers
Status: COMPLETED
Conditions: Heart Failure With Preserved Ejection Fraction (HFpEF)
Interventions: DRUG: AZD4831|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Microdevice In Ovarian, Fallopian Tube, And Peritoneal Cancer
Status: RECRUITING
Conditions: Ovarian Cancer|Fallopian Tube Cancer|Peritoneal Cancer|Ovarian Cancer Stage III|Ovarian Cancer Stage IV|Fallopian Tube Cancer Stage IV|Fallopian Tube Cancer Stage III
Interventions: COMBINATION_PRODUCT: Microdevice
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Dendritic Cell (DC) Activated Cytokine-induced Killer Cell (DCIK) Combined With DC Treatment for Glioma
Status: UNKNOWN
Conditions: Malignant Glioma
Interventions: BIOLOGICAL: Biological: DC activated CIK combined with DC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Using CBUS™ System for Ultrasound Breast Imaging Designed for Breast Tumor Diagnosis
Status: TERMINATED
Conditions: Breast Cancer
Interventions: DEVICE: Ultrasound breast scanning
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Assessing Efficacy and Safety of Flexible Dosing With Vardenafil in Subjects With Erectile Dysfunction and Hyperlipidemia
Status: COMPLETED
Conditions: Erectile Dysfunction
Interventions: DRUG: Levitra (Vardenafil, BAY38-9456)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Standard ART Practice vs. Trophectoderm Biopsy and Whole Chromosome Analysis
Status: UNKNOWN
Conditions: Infertility|Recurrent Pregnancy Loss
Interventions: GENETIC: Next Generation Sequencing after Blastocyst biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: The Effects of a Novel Lifestyle Intervention Program on Insulin Sensitivity in Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes|Fatty Liver, Nonalcoholic
Interventions: BEHAVIORAL: Low-calorie diet supported by an app-guided digital education program, nutritional coaching calls via phone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Learn About the Study Medicine Called Infliximab (Genetical Recombination)[Infliximab Biosimilar 3] in People With Rheumatoid Arthritis, Ulcerative Colitis, Crohn's Disease, or Psoriasis
Status: COMPLETED
Conditions: Arthritis, Rheumatoid|Colitis, Ulcerative|Crohn Disease|Psoriasis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Implant Placement Using a Newly Designed Single Drill Versus Conventional Sequential Drills
Status: COMPLETED
Conditions: Implant Complication
Interventions: OTHER: drill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Association of Lenalidomide, Ixazomib, Dexamethasone and Daratumumab in Newly Diagnosed Standard Risk Multiple Myeloma
Status: RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: Ixazomib|DRUG: Lenalidomide|DRUG: Dexamethasone|DRUG: Daratumumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Micronutrient Supplementation in PCO-syndrome
Status: COMPLETED
Conditions: Polycystic Ovary Syndrome|Infertility, Female|Micronutrient Deficiency
Interventions: DIETARY_SUPPLEMENT: Profertil female|DIETARY_SUPPLEMENT: Folic acid 400 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Piloting a Patient-Reported Outcome Measure for Opioid Use Disorder Recovery in a Clinical Setting
Status: ENROLLING_BY_INVITATION
Conditions: Substance Use Disorders|Opioid Use Disorder
Interventions: OTHER: Patient Reported Outcome Measure
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Clinico-biological Characterization and Survival of Patients With Adult T-cell Leukemia / Lymphoma (ATL) and Patients Chronically Infected With the HTLV-1 Virus (HTLV-OBS)
Status: RECRUITING
Conditions: Lymphoproliferation Induced by HTLV-1|HTLV-1 Adult T-cell Lymphoma / Leukemia|HTLV-1 Infection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A First Time in Human Phase 1 Open-Label Study of the COVIDITY Vaccine Administered by Needle-free Injection
Status: ACTIVE_NOT_RECRUITING
Conditions: COVID-19
Interventions: BIOLOGICAL: COVIDITY (SCOV1 and SCOV2) administered via needle-free intradermal injection|BIOLOGICAL: COVIDITY (SCOV1 and SCOV2) administered via needle-free intramuscular injection|BIOLOGICAL: COVIDITY (SCOV2 only) administered via needle-free intradermal injection to vaccine naive and/or previously vaccinated participants|BIOLOGICAL: COVIDITY (SCOV2 only) administered via needle-free intramuscular injection to vaccine naive and/or previously vaccinated participants|BIOLOGICAL: COVIDITY (SCOV2 only) administered via needle-free intradermal injection to previously infected participants|BIOLOGICAL: COVIDITY (SCOV2 only) administered via needle-free intramuscular injection to previously infected participants
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: CD19/CD20 Dual-CAR-T in B-cell Leukemia Patients
Status: COMPLETED
Conditions: B-cell Leukemia
Interventions: BIOLOGICAL: CD19/CD20 Dual-CAR-T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Infusion of Allogeneic Mesenchymal Stem Cells in Patients With Diffuse Cutaneous Systemic Sclerosis With Refractory Pulmonary Involvement
Status: AVAILABLE
Conditions: Systemic Sclerosis Pulmonary|Pulmonary Hypertension|Pulmonary Fibrosis
Interventions: BIOLOGICAL: Mesenchymal Stem Cells from Wharton ́s jellyintravenous infusion of Mesenchymal Stem Cells from Wharton ́s jelly
Study Type: EXPANDED_ACCESS
Clinical trial: Comparison of the Effects of Green Exercise Programs Including Resistance and Aerobic Exercises
Status: RECRUITING
Conditions: Physical Inactivity
Interventions: BEHAVIORAL: Aerobic Exercise|BEHAVIORAL: Aerobic + resistance exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Sonography-guided Resection of Brain Mass Lesions
Status: RECRUITING
Conditions: Tumor, Brain|Arteriovenous Malformations|Cavernoma|Intracerebral Hematoma
Interventions: DEVICE: Sonography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Two-weeks of Time Restricted Feeding on Basal and Postprandial Metabolism in Healthy Men
Status: COMPLETED
Conditions: Metabolic Health
Interventions: BEHAVIORAL: Time restricted feeding|BEHAVIORAL: Caloric restriction
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Trial and Follow-up of the Efficacy of Two-stage Integrated Treatment for Chinese Schizophrenia Inpatients
Status: UNKNOWN
Conditions: Schizophrenia
Interventions: DRUG: Olanzapine|OTHER: Cognitive behavior therapy|OTHER: Rehabilitation treatment|OTHER: Case management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT