pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Single Dose Pharmaco-Diagnostic for Peripheral Nerve Continuity After Trauma
Status: TERMINATED
Conditions: Nerve Injury
Interventions: DRUG: 4-Aminopyridine|DRUG: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Desmopressin on the Nocturnal Micturition Frequency in Patients With Parkinson Disease
Status: TERMINATED
Conditions: Parkinson Disease
Interventions: DRUG: Desmotabs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Sorafenib Tosylate in Treating Patients With Liver Cancer Who Have Undergone a Liver Transplant
Status: COMPLETED
Conditions: Adult Primary Hepatocellular Carcinoma|Advanced Adult Primary Liver Cancer|Localized Resectable Adult Primary Liver Cancer|Localized Unresectable Adult Primary Liver Cancer|Recurrent Adult Primary Liver Cancer
Interventions: DRUG: sorafenib tosylate|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Conventional Photorefractive Keratectomy (PRK) in U.S. Army Personnel, Substudy of: Initial Evaluation of Excimer Laser Keratorefractive Surgery in U.S. Army Personnel
Status: COMPLETED
Conditions: Myopia
Interventions: PROCEDURE: Photorefractive Keratectomy (PRK)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Effectiveness of HIV-1 LAI gp120 (an HIV Vaccine) Given With or Without HIV-1 MN rgp120 (Another HIV Vaccine) to HIV-Negative Volunteers
Status: COMPLETED
Conditions: HIV Infections|HIV Seronegativity
Interventions: BIOLOGICAL: Salmonella typhi CVD 908-HIV-1 LAI gp 120 (VVG 203)|BIOLOGICAL: Aluminum hydroxide|BIOLOGICAL: MF59|BIOLOGICAL: rgp120/HIV-1MN
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: DEX Combined With RTX, CSA and IVIG in the Management of Newly Diagnosed ITP Patients
Status: UNKNOWN
Conditions: Immune Thrombocytopenia
Interventions: DRUG: DEX Combined With RTX, CSA and IVIG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Utility of Ultrasound in Identification of Midline and Placement of Epidural in Severely Obese Parturients
Status: COMPLETED
Conditions: Epidural Anesthesia|Spinal Ultrasound|Obesity
Interventions: PROCEDURE: Palpation|DEVICE: Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: QL1101 in Combination With JS001 in Patients With pMMR/MSS Refractory Metastatic Colorectal Cancer
Status: UNKNOWN
Conditions: Refractory Metastatic Colorectal Cancer|pMMR|MSS
Interventions: DRUG: Bevacizumab|DRUG: Tripleitriumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lateral Rectus Resection Versus Lateral Rectus Plication in Patients With Residual Esotropia
Status: UNKNOWN
Conditions: Strabismus
Interventions: PROCEDURE: Lateral rectus plication|PROCEDURE: Lateral rectus Resection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Phonophoresis of Lidocaine Gel and Its Effect on Sensory Blockage
Status: COMPLETED
Conditions: Pain|Impairment, Light Touch Sensation
Interventions: DEVICE: pulsed ultrasound device with lidocaine|OTHER: off device|DEVICE: continuous ultrasound device with lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Electrographic Flow Mapping Validation in Patients With Persistent Atrial Fibrillation (EVAL AF)
Status: WITHDRAWN
Conditions: Persistent Atrial Fibrillation|Longstanding Persistent Atrial Fibrillation
Interventions: DEVICE: Electrographic Flow Mapping
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Open-Label Study Evaluating Synera® in the Treatment of Patients With Carpal Tunnel Syndrome
Status: COMPLETED
Conditions: Carpal Tunnel Syndrome
Interventions: DRUG: Synera (lidocaine 70 mg and tetracaine 70 mg) topical patch
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy, Safety, and Tolerability of Mirabegron in Men With OAB Symptoms While Taking Tamsulosin Hydrochloride for Lower Urinary Tract Symptoms (LUTS) Due to Benign Prostatic Hyperplasia (BPH)
Status: COMPLETED
Conditions: Benign Prostatic Hyperplasia|Overactive Bladder
Interventions: DRUG: Mirabegron|DRUG: Placebo|DRUG: Tamsulosin Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Methotrexate Infusion and Intrasilicone Injection During Diabetic Vitrectomy
Status: COMPLETED
Conditions: Diabetic Retinopathy|Vitreomacular Traction
Interventions: DRUG: Methotrexate 25 MG/ML|PROCEDURE: parsplana vitrectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Efficacy of Immunoglobulin Plus Prednisolone in Reducing Coronary Artery Lesion in Patients With Kawasaki Disease
Status: RECRUITING
Conditions: Kawasaki Disease
Interventions: DRUG: IVIG|DRUG: Aspirin|DRUG: Prednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intervention Assessing the Role of Exercise Program and Nutrition Supplement for Sarcopenia
Status: COMPLETED
Conditions: Sarcopenia
Interventions: BEHAVIORAL: Exercise program alone|DIETARY_SUPPLEMENT: Combined exercise program and nutrition supplement|OTHER: Waitlist control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of a Blue Monochromatic Light Intervention on Evening-type Individuals' Sleep and Circadian Rhythms
Status: COMPLETED
Conditions: Circadian Rhythm Sleep Disorder, Delayed Sleep Phase|Sleep
Interventions: OTHER: Blue light exposure|OTHER: Full spectrum light exposure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Reduction of Catheterization Radiation Exposure Pad
Status: COMPLETED
Conditions: Radiation; Exposure Occupational|Coronary Interventions
Interventions: DEVICE: (sham) radiation absorbing drape (RADPAD®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of PEG 3350 for Treatment of Chronic Constipation
Status: UNKNOWN
Conditions: Constipation - Functional
Interventions: DRUG: PEG 3350|DRUG: Lactulose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Brace Versus No Brace for the Treatment of Thoracolumbar Burst Fractures Without Neurologic Injury
Status: COMPLETED
Conditions: Thoracolumbar Burst Fractures Without Neurologic Deficit
Interventions: OTHER: TLSO|OTHER: No Orthosis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Homeopathic Vaccine Trial
Status: UNKNOWN
Conditions: Healthy Volunteers
Interventions: BIOLOGICAL: MMR|BIOLOGICAL: Tdap|OTHER: Diphtherinum®|OTHER: Pertussinum®|OTHER: Tetanotxicum®|OTHER: Morbilinum®|OTHER: Ourlianum®|OTHER: Sterile saline|OTHER: Sugar pellets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Effects of the Mediterranean Diet During Pregnancy on the Onset of Allergies in the Offspring
Status: RECRUITING
Conditions: Allergies|Obesity|Gestational Complications|Gestational Weight Gain|Perinatal Condition|Birth Weight|Chronic Diseases in Children|Breast Feeding
Interventions: OTHER: Nutritional intervention based on Mediterranean Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Pharmacokinetic Evaluation of Intranasal Nalmefene
Status: COMPLETED
Conditions: Pharmacokinetics
Interventions: DRUG: Nalmefene Hydrochloride|DRUG: Nalmefene
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: the PHENOSAR Trial: Use of Antibiotics in Treatment of Sarcoidosis
Status: NOT_YET_RECRUITING
Conditions: Sarcoidosis, Pulmonary|Sarcoidosis Skin
Interventions: RADIATION: FDG-PET/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I Clinical Trial of Recombinant SARS-CoV-2 Spike Protein Vaccine (CHO Cell) for the Prevention of COVID-19
Status: ACTIVE_NOT_RECRUITING
Conditions: COVID-19
Interventions: BIOLOGICAL: 202-CoV low adjuvant dose|BIOLOGICAL: 202-CoV low antigen dose|BIOLOGICAL: 202-CoV standard dose|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Combination Plerixafor (AMD3100)and Bortezomib in Relapsed or Relapsed/Refractory Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Plerixafor|DRUG: bortezomib|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sinemet for Spasticity and Function in Amyotrophic Lateral Sclerosis and Primary Lateral Sclerosis
Status: COMPLETED
Conditions: Amyotrophic Lateral Sclerosis|Motor Neuron Disease
Interventions: DRUG: carbidopa-levodopa|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of ARi With OpSens SavvyWire
Status: RECRUITING
Conditions: Aortic Valve Insufficiency
Interventions: DEVICE: Transcatheter Aortic Valve Replacement (TAVR)|DEVICE: Balloon Aortic Valvuloplasty (BAV)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: TheraCal LC Coronal Pulpotomy and MTA Coronal Pulpotomy in Mature Permanent Molars
Status: ACTIVE_NOT_RECRUITING
Conditions: Irreversible Pulpitis|Deep Caries
Interventions: DRUG: Theracal LC|DRUG: MTA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Oral Treprostinil in Subjects With Pulmonary Hypertension Associated With Pulmonary Fibrosis
Status: WITHDRAWN
Conditions: Pulmonary Hypertension|Pulmonary Fibrosis
Interventions: DRUG: Oral treprostinil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Meditation Versus Education for Improving Depression in Chronic Pain, a Randomized Controlled Trial
Status: COMPLETED
Conditions: Chronic Pain|Depression
Interventions: BEHAVIORAL: Health Enhancement Program (HEP)|BEHAVIORAL: Sahaj Samadhi Meditation (SSM)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Proof-of-concept Study of LymphMonitor 1.0 to Assess the Lymphatic Vessel Function
Status: COMPLETED
Conditions: Lymphedema|Secondary Lymphedema
Interventions: COMBINATION_PRODUCT: Lymphatic clearance measurement
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Reappraising Intergeneration Relationships in Dementia Caregiving
Status: UNKNOWN
Conditions: Alzheimer Dementia
Interventions: BEHAVIORAL: Perspective Taking Reappraisal|OTHER: Basic Skill Building
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Acute Leukemia Relapse After Allotransplantation
Status: UNKNOWN
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Combined use of azacitidine, valproic acid, hydroxurea and eventually donor leukocyte infusions.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intravenous Estramustine With Taxol in Hormone Refractory Prostate Adenocarcinoma
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: Estramustine|DRUG: Taxol
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Remote Monitoring System for Patients, Who Had Myocardial Infarction
Status: UNKNOWN
Conditions: Myocardial Infarction|Adherence, Patient
Interventions: DEVICE: The remote monitoring system
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Cocoa Flavanols for Modulating Immune Response and Accelerating Recovery
Status: COMPLETED
Conditions: Surgical Recovery
Interventions: DRUG: CocoaVia®|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Fasting Mimicking Diet (FMD) in Women With Polycystic Ovary Syndrome (PCOS)
Status: ACTIVE_NOT_RECRUITING
Conditions: Polycystic Ovarian Syndrome
Interventions: DIETARY_SUPPLEMENT: Fasting mimicking diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Adverse Events and Change in Disease Activity With Oral Capsules of Galicaftor/Navocaftor/ABBV-119 or Galicaftor/Navocaftor/ABBV-576 Combination Therapies in Adult Participants With Cystic Fibrosis
Status: TERMINATED
Conditions: Cystic Fibrosis (CF)
Interventions: DRUG: ABBV-576|DRUG: Galicaftor|DRUG: Placebo|DRUG: Navocaftor|DRUG: ABBV-119
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Long-term Effect of Dupilumab on Skin Barrier Function in Pediatric Participants With Atopic Dermatitis
Status: RECRUITING
Conditions: Dermatitis Atopic
Interventions: DRUG: dupilumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vitamin D Supplementation and Glycemic Control Improvement Among Type 1 Diabetic Children
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus|Vitamin D Deficiency
Interventions: DIETARY_SUPPLEMENT: vitamin D supplements (2000 IU/day)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Planned Conversion From TAC to SRL-based Regimen in de Novo Kidney Transplant Recipients
Status: COMPLETED
Conditions: Kidney Transplant
Interventions: DRUG: Conversion from Tacrolimus to Sirolimus|DRUG: Maintenance on tacrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Trans-Nasal Afferent Loop Decompression on Post-Pancreaticoduodenectomy Pancreatic Fistula
Status: COMPLETED
Conditions: Pancreatic Fistula|Pancreaticoduodenectomy|Complication of Surgical Procedure
Interventions: PROCEDURE: Trans-Nasal Afferent Loop Decompression|PROCEDURE: Without Trans-Nasal Afferent Loop Decompression
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Walking After Surgery to Improve Recovery and Outcomes After Surgery, AIRTECH Study
Status: RECRUITING
Conditions: Lung Carcinoma
Interventions: OTHER: Best Practice|OTHER: Health Promotion and Education|OTHER: Medical Device Usage and Evaluation|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Outcome of Palliative Management of Malignant Large Bowel Obstruction w/Colorectal Stents or Surgery
Status: COMPLETED
Conditions: Large Bowel Obstruction
Interventions: DEVICE: Luminal stents|PROCEDURE: Minimally Invasive Surgical Bowel Diversion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Myocardial Infarction Triage and Intervention Project (MITI)
Status: COMPLETED
Conditions: Cardiovascular Diseases|Coronary Disease|Heart Diseases|Myocardial Infarction|Myocardial Ischemia
Interventions: DRUG: tissue plasminogen activator
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Ultrasound-Guided Glenohumeral Steroid Injection
Status: COMPLETED
Conditions: Adhesive Capsulitis of Shoulder
Interventions: PROCEDURE: Glenohumeral triamcinolone injection by anterior approach|PROCEDURE: Glenohumeral triamcinolone injection by posterior approach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Surgical Treatments for Neuroma Pain in Amputees
Status: ENROLLING_BY_INVITATION
Conditions: Pain, Neuropathic|Amputation Neuroma|Phantom Limb Pain
Interventions: PROCEDURE: TMR|PROCEDURE: RPNI|PROCEDURE: VDMT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assisted Hatching Versus Endometrial Scratch in Recurrent Implantation Failure
Status: UNKNOWN
Conditions: Recurrent Implantation Failure
Interventions: PROCEDURE: endometrial scratch|PROCEDURE: assisted hatching|PROCEDURE: controlled ovarian hyperstimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Immunogenicity of Fluzone® With and Without JVRS-100 in Elderly Subjects
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Fluzone® vaccine with JVRS-100 adjuvant or Fluzone alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Positron Emission Tomography (PET)/Computed Tomography (CT) and Roentgen in Lung Cancer: Evaluation of Patients in General Practice
Status: UNKNOWN
Conditions: Lung Cancer
Interventions: RADIATION: PET/CT (low-dose)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Alveolar Recruitment Maneuver During Cesarean Section Improves Lung Compliance
Status: COMPLETED
Conditions: Decreased Lung Compliance|Hypoxia|Hypercapnia|Atelectasis|Pneumonia
Interventions: PROCEDURE: Alveolar Recruitment maneuver
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Eltrombopag Taste Testing in Healthy Adult Volunteers
Status: COMPLETED
Conditions: Healthy Subjects|Purpura, Thrombocytopenic, Idiopathic
Interventions: DRUG: eltrombopag
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Study of Betalutin for Treatment of Relapsed or Refractory Non-Hodgkin Lymphoma (LYMRIT-37-05)
Status: COMPLETED
Conditions: Relapsed, Diffuse Large B-cell Lymphoma|Refractory Diffuse Large B-Cell Lymphoma
Interventions: DRUG: Betalutin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Oral SCIO-469 Pharmacokinetics (Study of a Drug in the Body to Watch How the Drug is Absorbed, Distributed, Metabolized and Eliminated Over a Period of Time) in the Body of Female Patients With Active Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Oral SCIO-469 capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial of XZP-6019 Tablets in Healthy Subjects
Status: UNKNOWN
Conditions: Non-alcoholic Fatty Liver Disease
Interventions: DRUG: XZP-6019 tablet|DRUG: Placebo|DRUG: XZP-6019 tablet|DRUG: XZP-6019 tablet|DRUG: XZP-6019 tablet|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Sapanisertib, Combination of Sapanisertib With MLN1117, Paclitaxel and Combination of Sapanisertib With Paclitaxel in Women With Endometrial Cancer
Status: COMPLETED
Conditions: Endometrial Neoplasms
Interventions: DRUG: Paclitaxel|DRUG: Sapanisertib|DRUG: MLN1117
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adjuvant Radiation Therapy Compared With Observation After Surgery in Treating Women With Estrogen Receptor Positive or Progesterone Receptor Positive Ductal Carcinoma In Situ of the Breast Who Are Receiving Tamoxifen or Anastrozole
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: DRUG: anastrozole|DRUG: tamoxifen citrate|PROCEDURE: adjuvant therapy|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: PET-Adjusted Intensity Modulated Radiation Therapy and Combination Chemotherapy in Treating Patients With Stage II-IV Non-small Cell Lung Cancer
Status: COMPLETED
Conditions: Metastatic Malignant Neoplasm in the Brain|Recurrent Non-Small Cell Lung Carcinoma|Stage IIA Non-Small Cell Lung Carcinoma|Stage IIB Non-Small Cell Lung Carcinoma|Stage IIIA Non-Small Cell Lung Cancer|Stage IIIB Non-Small Cell Lung Cancer|Stage IV Non-Small Cell Lung Cancer
Interventions: DRUG: Carboplatin|PROCEDURE: Computed Tomography|RADIATION: Intensity-Modulated Radiation Therapy|DRUG: Paclitaxel|PROCEDURE: Positron Emission Tomography|RADIATION: Proton Beam Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Side-by-Side Comparison of P200TE and Spectral OCT/SLO on Diseased Eyes
Status: UNKNOWN
Conditions: Retinal Disease|Glaucoma
Interventions: DEVICE: P200TE|DEVICE: Spectral OCT/SLO
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Evaluation of MST-188 in Acute Lower Limb Ischemia
Status: TERMINATED
Conditions: Acute Limb Ischemia
Interventions: DRUG: MST-188|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study on the Safety and Tolerability, Pharmacokinetics and Pharmacodynamics of SHR-2004 Injection in Adult Patients With Atrial Fibrillation
Status: NOT_YET_RECRUITING
Conditions: Atrial Fibrillation
Interventions: DRUG: SHR-2004 injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Assessment of Osteopathic Manipulative Treatment in the Suboptimal Breastfeeding Behaviour
Status: COMPLETED
Conditions: Breast Feeding, Exclusive
Interventions: OTHER: Osteopathic Manipulative Treatment|OTHER: No Osteopathic manipulative Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Role of Concomitant Diseases in Postoperative Complications Risk Stratification.
Status: RECRUITING
Conditions: Coronary Heart Disease|Anemia|Bronchial Asthma|Stroke|Epilepsy|Parkinson's Disease|Heart Rhythm Disorders|Alzheimer's Disease|Neuromuscular Diseases|Diabetes|Chronic Heart Failure|Chronic Obstructive Pulmonary Disease|Chronic Kidney Diseases
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Yoga Vs. Stretching on Chronic Back Pain
Status: COMPLETED
Conditions: Chronic Non-specific Low Back Pain
Interventions: BEHAVIORAL: Yoga|BEHAVIORAL: Exercise|BEHAVIORAL: Self-care book recommendations
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transplant Regimen Adherence for Kidney Recipients by Engaging Information Technologies: The TAKE IT Trial
Status: COMPLETED
Conditions: Kidney Transplant
Interventions: BEHAVIORAL: TAKE IT Strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: PRESENCE Project: An Early Palliative Care Intervention in Brain Tumors
Status: TERMINATED
Conditions: Malignant Brain Tumors
Interventions: OTHER: Research Questionnaires|OTHER: Palliative Care Team|OTHER: Educational Information Session for Patients and Caregivers|OTHER: Contact every 2 weeks|OTHER: Follow-up Surgical Visit Session|OTHER: Medical and/or Radiation Oncology Appointment Session
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Influence of Menopausal Status on Myocardial Stiffness and Exercise Capacity Among Female Masters Endurance Athletes.
Status: NOT_YET_RECRUITING
Conditions: Myocardial Stiffness
Interventions: DIAGNOSTIC_TEST: Stress Echocardiogram|DIAGNOSTIC_TEST: Cardiovascular Magnetic Imaging (cMRI)|DIAGNOSTIC_TEST: Cardiac Magnetic Resonance Elastography (cMRE)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Ivermectin Safety in Small Children
Status: RECRUITING
Conditions: Scabies
Interventions: DRUG: Oral ivermectin|DRUG: Permethrin Cream|OTHER: Placebo tablet|OTHER: Placebo cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessments of Genetic Counseling Augmented With an Educational Video or Pamphlet Versus Traditional Counseling
Status: COMPLETED
Conditions: Quality|Prostate Cancer|Gastrointestinal Cancer|Gynecologic Cancer|Ovarian Cancer|Pancreatic Cancer
Interventions: OTHER: Educational video and pamphlet|OTHER: Traditional genetic counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Non-Interventional Study of NovoSeven® Used in Patients With Haemophilia A and B With Inhibitors When Undergoing Surgery
Status: COMPLETED
Conditions: Congenital Bleeding Disorder|Haemophilia A With Inhibitors|Haemophilia B With Inhibitors
Interventions: DRUG: eptacog alfa (activated)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Analysis and Suppression of Tremor During Grasp Using Ultrasound Imaging and Electrical Stimulation
Status: RECRUITING
Conditions: Parkinson Disease|Essential Tremor
Interventions: DEVICE: Ultrasound Imaging|DEVICE: Electromyography|DEVICE: Inertial Measurement Units (IMU)|DEVICE: Functional Electrical Stimulation (FES)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Evaluation of Therapeutic Effect of 0.5 mg Colchicine and 5 mg Prednisolone on Oral Aphthae
Status: UNKNOWN
Conditions: Oral Aphthae
Interventions: DRUG: Prednisolone|DRUG: Colchicine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of rTMS in Combination With a Low-carbohydrate Diet in Patients With Obesity
Status: COMPLETED
Conditions: Obesity|Anxiety
Interventions: DEVICE: rTMS|DEVICE: sham rTMS|OTHER: Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Surgery Or Lifestyle Intervention for Type 2 Diabetes (SOLID)
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: PROCEDURE: Roux-en-Y Gastric Bypass surgery|PROCEDURE: Laparoscopic Adjustable Gastric Banding surgery|BEHAVIORAL: Intensive Lifestyle Modification
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Intratumoral Injections of TTI-621 in Subjects With Relapsed and Refractory Solid Tumors and Mycosis Fungoides
Status: TERMINATED
Conditions: Solid Tumors|Mycosis Fungoides|Melanoma|Merkel-cell Carcinoma|Squamous Cell Carcinoma|Breast Carcinoma|Human Papillomavirus-Related Malignant Neoplasm|Soft Tissue Sarcoma
Interventions: DRUG: TTI-621 Monotherapy|DRUG: TTI-621 + PD-1/PD-L1 Inhibitor|DRUG: TTI-621 + pegylated interferon-α2a|OTHER: TTI-621 + T-Vec|OTHER: TTI-621 + radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Platelet-rich Plasma, Corticosteroid, or Lidocaine for Acromioclavicular Joint Pain
Status: RECRUITING
Conditions: Acromioclavicular Sprain
Interventions: DRUG: Lidocaine injection|DRUG: Corticosteroid Injection|DRUG: Protein Rich Plasma(PRP) Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: XERECEPT® (hCRF) for Primary Glioma Patients Requiring Dexamethasone to Treat Peritumoral Brain Edema
Status: WITHDRAWN
Conditions: Brain Edema|Brain Tumor
Interventions: DRUG: hCRF|DRUG: placebo hCRF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Routine Therapy Plus Moxifloxacin in Advanced Breast Cancer
Status: COMPLETED
Conditions: Advanced Breast Cancer|Antibiotic|Stable Disease With a Trend of Progression
Interventions: DRUG: Moxifloxacin Hydrochloride 400mg Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating Diltiazem in Combination With Standard Treatment in the Management of Patients Hospitalized With COVID-19 Pneumonia
Status: WITHDRAWN
Conditions: COVID-19
Interventions: DRUG: DILTIAZEM TEVA 60 mg or placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: TREAD-20: Trial of Hyalgan Three Injection-Regimen for the Treatment of Knee Pain Due to Osteoarthritis
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DRUG: Hyalgan (sodium hyaluronate)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: The Public Private Partnership Addressing Literacy-Numeracy to Improve Diabetes Care
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: OTHER: Enhanced Diabetes Education|OTHER: Standard Diabetes Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study to Evaluate Effect of Food on Bioavailability of Single 3 mg Tablet and Pharmacokinetics (PK) of Multiple 3 mg Doses in Healthy Adult Smokers
Status: COMPLETED
Conditions: Smoking Cessation
Interventions: DRUG: Cytisinicline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sustaining Smoking Cessation in Smokers With Kids With Asthma
Status: COMPLETED
Conditions: Asthma|Smoking Cessation
Interventions: BEHAVIORAL: PAM|BEHAVIORAL: PAM-Enhanced/Asthma Counseling Phone Calls|BEHAVIORAL: Follow-Up Phone Calls - Child Wellness Topic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Glucosanol™ in Body Weight Reduction
Status: COMPLETED
Conditions: Overweight and Obesity
Interventions: DIETARY_SUPPLEMENT: Glucosanol 350mg|DIETARY_SUPPLEMENT: Glucosanol 500mg|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Bioequivalence of the Metformin Component of the Fixed Dose Combination Tablet of Canagliflozin and Metformin Extended Release With Respect to Metformin XR Tablet Coadministered With Canagliflozin in Healthy Fed and Fasted Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Canagliflozin and Metformin Extended Release (XR) Fixed Dose Combination [FDC]|DRUG: Canagliflozin|DRUG: Metformin Extended Release (XR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Pilot Study of (MR) Imaging With Pyruvate (13C) to Detect High Grade Prostate Cancer
Status: RECRUITING
Conditions: Prostate Cancer
Interventions: DRUG: Hyperpolarized 13C-Pyruvate|DRUG: Hyperpolarized 13C,15N2-urea|PROCEDURE: Magnetic Resonance Spectroscopic Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Clinical Efficacy of Tranexamic Acid and ε-Aminocaproic Acid in Reducing Blood Loss Following Total Knee Replacement
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DRUG: Tranexamic Acid (TXA)|DRUG: ε-Aminocaproic Acid (EACA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Long-term Extension Study of the Safety, Tolerability, and Efficacy of Aclidinium Bromide in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD) (LAS-MD-36)
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Aclidinium bromide|DRUG: Aclidinium bromide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Exploratory Study of the Relevance of a Blood Test in the Management of Patients in the Context of Colorectal Cancer Screening
Status: RECRUITING
Conditions: Colorectal Cancer
Interventions: DIAGNOSTIC_TEST: Blood sample|OTHER: Tumor tissue|OTHER: stool collection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of CAR T-Cells Targeting the GD2 With IL-15+iCaspase9 for Relapsed/Refractory Neuroblastoma or Relapsed/Refractory Osteosarcoma
Status: RECRUITING
Conditions: Neuroblastoma|Osteosarcoma
Interventions: BIOLOGICAL: iC9.GD2.CAR.IL-15 T-cells|DRUG: Cyclophosphamide|DRUG: Fludarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influenza Vaccine To Prevent Adverse Vascular Events:Pilot
Status: COMPLETED
Conditions: Heart Failure
Interventions: DRUG: inactivated trivalent influenza vaccine|OTHER: Sterile saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of LY3522348 in Healthy Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: LY3522348|DRUG: Placebo|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Cardiometabolic Health Program Linked With Clinical-Community Support and Mobile Health Telemonitoring to Reduce Health Disparities
Status: RECRUITING
Conditions: Hypertension|High Blood Pressure|Diabetes|Chronic Kidney Diseases
Interventions: BEHAVIORAL: LINKED-HEARTS Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effect of Gemcabene on Insulin Sensitivity in Nondiabetic Subjects
Status: COMPLETED
Conditions: Insulin Sensitivity
Interventions: DRUG: Gemcabene 900 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effects of Antihypertensive Agents on Central Blood Pressure in Healthy Participants and Participants With Hypertension (MK-0000-166) (COMPLETED)
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Placebo|DRUG: Comparator: Amlodipine|DRUG: Comparator: ISMN ER
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Project TEAM (Teens Making Environmental and Activity Modifications)
Status: COMPLETED
Conditions: Transition-age Youth|Developmental Disabilities|Cerebral Palsy|Autism|Intellectual Disability
Interventions: BEHAVIORAL: Project TEAM|BEHAVIORAL: Matched Comparison
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Short-term Synbiotic Treatment on Plasma P-cresol Levels in Hemodialysis Patients
Status: UNKNOWN
Conditions: Hemodialysis
Interventions: DIETARY_SUPPLEMENT: SYNBIOTIC (Probinul neutro®)|DIETARY_SUPPLEMENT: PLACEBO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Timing of Transmural Stent Removal in Necrotizing Pancreatitis
Status: NOT_YET_RECRUITING
Conditions: Acute Pancreatitis|Necrotizing Pancreatitis|Walled-Off Necrosis
Interventions: PROCEDURE: Stent removed by the novel strategy|PROCEDURE: Stent removed by the conventional strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early and Whole Course Nutritional Support by Nutren® Optimum During IMRT for Nasopharyngeal Carcinoma
Status: UNKNOWN
Conditions: Nasopharyngeal Carcinoma|Nutritional Support
Interventions: RADIATION: Radiotherapy|DRUG: Chemotherapy|DIETARY_SUPPLEMENT: Nutren® Optimum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of NBO in Acute Intracerebral Hemorrhage
Status: UNKNOWN
Conditions: Normobaric Oxygen|Cerebral Hemorrhage
Interventions: OTHER: Normobaric Oxygen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Outcomes of Septic Shock Patients Treated With a Metabolic Resuscitation Bundle Consisting of Intravenous Hydrocortisone, Ascorbic Acid and Thiamine.
Status: COMPLETED
Conditions: Septic Shock|Ascorbic Acid Deficiency
Interventions: DRUG: Intravenous Ascorbic Acid
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Proteomics for Identification of Hyperoxia-induced Changes in Protein Expression
Status: UNKNOWN
Conditions: Hyperoxia
Interventions: DRUG: Oxygen (FiO2 1,0)|DEVICE: Facemask
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Biomarkers in Tissue Samples From Patients With Breast Cancer Treated With Bevacizumab
Status: COMPLETED
Conditions: Breast Cancer
Interventions: GENETIC: DNA analysis|GENETIC: gene expression analysis|GENETIC: polymorphism analysis|GENETIC: protein expression analysis|OTHER: immunohistochemistry staining method|OTHER: laboratory biomarker analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Doxycycline- and Furazolidone-containing Quadruple Regimen is Superior of Tailored Therapy
Status: UNKNOWN
Conditions: Helicobacter Pylori Infection
Interventions: DRUG: Doxycycline|DRUG: Furazolidone|DRUG: Esomeprazole|DRUG: Colloidal Bismuth Subcitrate|DRUG: Sensitivity antibiotics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Differential Vascular and Endocrine Effects of Valsartan/Sacubitril in Heart Failure With Reduced Ejection Fraction
Status: COMPLETED
Conditions: Heart Failure
Interventions: DRUG: Valsartan/Sacubitril or placebo|DRUG: Valsartan or placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Progressive Relaxation Exercises on Fatigue and Sleep Quality in İndividuals With Epilepsy
Status: COMPLETED
Conditions: Epilepsy|Sleep|Fatigue
Interventions: BEHAVIORAL: PROGRESSIVE RELAXATION EXERCISE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Microbiome Modulation on Sleep in Working People
Status: ACTIVE_NOT_RECRUITING
Conditions: Sleep
Interventions: DIETARY_SUPPLEMENT: Omnibiotic Stress Repair|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety, Tolerability, PD & PK of Calcipotriene 0.005% Foam, Under Maximal Use in 12-16 Year Olds With Plaque Psoriasis
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: Calcipotriene 0.005% Foam
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Comparison of Postprandial Inflammation in Lean and Obese Subjects
Status: COMPLETED
Conditions: Nutritional Intervention|Nutritional and Metabolic Diseases|Obesity
Interventions: DIETARY_SUPPLEMENT: High-fat meal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Stereotactic Radiosurgery or Whole Brain Radiation Therapy in Treating Patients With Newly Diagnosed Non-melanoma Brain Metastases
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Malignant Neoplasm|Metastatic Malignant Neoplasm in the Brain
Interventions: OTHER: Cognitive Assessment|OTHER: Quality-of-Life Assessment|RADIATION: Stereotactic Radiosurgery|RADIATION: Whole-Brain Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endoxifen in Adults With Hormone Receptor Positive Solid Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Hormone Receptor-Positive Breast|Gynecologic|Desmoid|Hormone Receptor-Positive Neoplasms
Interventions: DRUG: Z-Endoxifen
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lutein & Zeaxanthin in Pregnancy - Carotenoid Supplementation During Pregnancy: Ocular and Systemic Effects
Status: COMPLETED
Conditions: Nutrient Deficiency|Pregnancy Related
Interventions: DRUG: Carotenoid Group|DIETARY_SUPPLEMENT: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of CryoSpray Ablation(TM)to Determine Treatment Effect, Depth of Injury, and Side Effects in the Esophagus.
Status: COMPLETED
Conditions: Barrett's Esophagus|Esophageal Cancer
Interventions: DEVICE: Cryo Spray Ablation|DEVICE: Cryo Spray Ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Investigate the Effect of Continuous Versus Interrupted Subcutaneous Fat Closure in Reducing Surgical Site Infection Among Over-weight or Obese Women Who Are Undergoing Elective Caesarean Section
Status: NOT_YET_RECRUITING
Conditions: Overweight or Obese Women, Elective Lower Segment Cesarean Section
Interventions: PROCEDURE: continuous subcutaneous tissue closure|PROCEDURE: Interrupted subcutaneous tissue closure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Clinical Study to Evaluate the Pharmacokinetic Profiles and Safety of CKD-387 in Healthy Volunteers Under Fed Conditions
Status: COMPLETED
Conditions: Endocrine, Nutritional and Metabolic Diseases
Interventions: DRUG: CKD-387|DRUG: D484
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT