pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Evaluating the Effects of Kombucha as a Hyperglycemic Therapeutic Agent Within Diabetic Human Subjects
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: DIETARY_SUPPLEMENT: Ginger Kombucha|DIETARY_SUPPLEMENT: Ginger Water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Baseline V-RESOLVE Score Guided Versus Angiography Guided Stent Implantation in Coronary Bifurcation Lesions (CIT-RESOLVE II)
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: PROCEDURE: Baseline V-RESOLVE score-guided PCI|PROCEDURE: Angiography-guided PCI
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Takepron Intravenous 30 mg Specified Drug-use Survey [Acute Stress Ulcer and Acute Gastric Mucosal Lesions]
Status: COMPLETED
Conditions: Acute Stress Ulcer and Acute Gastric Mucosal Lesions
Interventions: DRUG: Lansoprazole
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Randomised, Phase II, Comparative Study With a Parallel Control for Evaluating the Efficacy and Safety of Combined Treatment of Lutropin Alpha and Recombinant Human Luteinizing Hormone in the Middle of the Controlled Ovarian Stimulation Follicular Phase in Women With Reduced Ovarian Reserve
Status: COMPLETED
Conditions: Infertility|Ovulation Induction
Interventions: DRUG: Recombinant human follicle stimulating hormone (r-hFSH)|DRUG: Recombinant human luteinizing hormone (r-hLH)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Percutaneous Microelectrolysis (MEP) Versus Ischemic Compression in Miofascial Trigger Points
Status: COMPLETED
Conditions: Myofascial Trigger Point Pain
Interventions: DEVICE: MEP|OTHER: Ischemic compression
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 3D Bioprinted Models for Predicting Chemotherapy Response in Colorectal Cancer With/Without Liver Metastases
Status: UNKNOWN
Conditions: Colorectal Cancer|Colorectal Cancer Liver Metastasis
Interventions: PROCEDURE: surgical resection|OTHER: adjuvant chemotherapy|OTHER: neoadjuvant therapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Gamma-tACS on Memory and Sleep
Status: COMPLETED
Conditions: Transcranial Alternating Current Stimulation|Aging|Cognitive Decline|Memory|Sleep
Interventions: DEVICE: Gamma transcranial alternating current stimulation|DEVICE: Control transcranial alternating current stimulation|DEVICE: EEG headband|DEVICE: Actigraphy wristband
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Oxfendazole in Mild Parenchymal Brain Cysticercosis
Status: NOT_YET_RECRUITING
Conditions: Brain Cysticercosis
Interventions: DRUG: Oxfendazole single dose|DRUG: Oxfendazole three doses|DRUG: albendazole plus praziquantel regime
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dronabinol for Post-operative Pain After Lumbar Fusion
Status: UNKNOWN
Conditions: Post-operative Pain
Interventions: DRUG: Dronabinol 2.5mg Cap|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Integration of Stepped Care for Perinatal Mood and Anxiety Disorders Among Women Attending MCH Clinics
Status: NOT_YET_RECRUITING
Conditions: Depression, Anxiety|Antenatal Depression|Postnatal Depression
Interventions: BEHAVIORAL: Integrated Perinatal Mental health program (systematic screening for PMAD, PM+ and tele-psychiatry)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Language Development Deficits and Early Interactive Music Intervention
Status: RECRUITING
Conditions: Dyslexia, Developmental|Language Development Disorders|Language Development
Interventions: BEHAVIORAL: Music intervention|BEHAVIORAL: Circus intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Positron Emission Tomography (PET) Imaging Study to Investigate the Biodistribution and Clearance of an Albumin Binding Domain Antibody (AlbudAb) GSK3128349 in Healthy Male Subjects
Status: COMPLETED
Conditions: Drug-Related Side Effects and Adverse Reactions
Interventions: DRUG: 89Zr-GSK3128349 1 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Feasibility Testing of Patient Reported Outcomes - Informed Symptom Management System (PRISMS)
Status: COMPLETED
Conditions: Colorectal Cancer|Bladder Cancer|Ovarian Cancer|Cervical Cancer|Uterine Cancer
Interventions: BEHAVIORAL: Patient-Reported Outcomes-Informed Symptom Management System (PRISMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Is the Evaluation of Anal Distensibility by Endoflip® Technique Useful for the Diagnosis of Anismus?
Status: UNKNOWN
Conditions: Anismus|Distal Constipation
Interventions: DEVICE: Anal EndoFLIP®|DIAGNOSTIC_TEST: Anal Manometry|DIAGNOSTIC_TEST: Defecography|DIAGNOSTIC_TEST: Electromyogram
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Intelligent Remote Intervention for High-risk Breast Cancer Populations
Status: NOT_YET_RECRUITING
Conditions: Ultrasonography|Breast Neoplasm Female|Breast Carcinoma|Health Education
Interventions: OTHER: the Remote Intervention|OTHER: the Traditional Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Immunological Memory Induced in Children by a Full 4 Dose Vaccination Schedule of 11 Valent Pneumococcal Conjugate Vaccine by Giving 1 Dose of Aventis Pasteur's 23-valent Pneumococcal Polysaccharide Vaccine (Pneumo 23)
Status: COMPLETED
Conditions: Prophylaxis Pneumococcal Vaccine
Interventions: BIOLOGICAL: Pneumococcal (vaccine)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy of Celecoxib Versus Placebo in the Treatment of Knee Osteoarthritis in Patients Who Were Unresponsive to Naproxen and Ibuprofen
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: DRUG: Celecoxib|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Safety and Efficacy of 3 Doses of ALX1-11 (50, 75, and 100µg) in the Treatment of Postmenopausal Osteoporosis
Status: COMPLETED
Conditions: Osteoporosis
Interventions: DRUG: ALX1-11 50 mcg|DRUG: placebo|DRUG: ALX1-11 75mcg|DRUG: ALX1-11
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing Inpatient COVID-19 Outcomes in 2 Different PT Dosing Groups
Status: WITHDRAWN
Conditions: COVID-19|Cardiopulmonary Disease|Weakness, Muscle|Hypoxia|Debility Due to Disease
Interventions: OTHER: Shorter duration higher frequency PT|OTHER: Standard PT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A1Check: the External Validation of a Machine Learning Model Predicting Colorectal Anastomotic Leakage
Status: RECRUITING
Conditions: Anastomotic Leak|Anastomotic Leak Large Intestine|Anastomotic Complication|Anastomotic Leak Rectum
Interventions: PROCEDURE: Colorectal resection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Efficacy and Safety of Apatinib Combined With Etoposide in Heavily Pretreated Advanced Non-small Cell Lung Cancer
Status: UNKNOWN
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: Apatinib|DRUG: Etoposide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Oral Supplementation in Improving Nutritional Status in Patients Undergoing Hematopoietic Stem Cell Transplant
Status: TERMINATED
Conditions: Malignant Neoplasm
Interventions: DIETARY_SUPPLEMENT: Boost Plus|DIETARY_SUPPLEMENT: Pro-Stat 101|DIETARY_SUPPLEMENT: Milkshake|OTHER: daily food diaries
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Moringa Oleifera on Metformin Plasma Level in Type 2 Diabetes Mellitus Patients
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DIETARY_SUPPLEMENT: Moringa oleifera tea
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Investigational Study of NKTR-214 Combined With Nivolumab in Japanese Participants With Advanced Solid Tumors
Status: COMPLETED
Conditions: Advanced Cancer
Interventions: BIOLOGICAL: NKTR-214|BIOLOGICAL: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity Study of BCG, H4:IC31, and H56:IC31 Revaccination in Healthy Adolescents
Status: COMPLETED
Conditions: Tuberculosis
Interventions: BIOLOGICAL: H4:IC31|BIOLOGICAL: H56:IC31|BIOLOGICAL: BCG|BIOLOGICAL: Control Sodium Chloride 0.9%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Magnetic Resonance Imaging Guided Gynecologic Brachytherapy
Status: COMPLETED
Conditions: Cervix Neoplasms|Uterine Neoplasms|Vaginal Neoplasms|Vulvar Neoplasms
Interventions: PROCEDURE: Brachytherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Induction of Pluripotent Stem Cells From Human Fibroblasts of DM1 Patients
Status: COMPLETED
Conditions: DM1
Interventions: OTHER: Clinical examination, skin biopsy, blood and urine sampling
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparative Clinical Evaluation of Daily Disposable Lenses in Symptomatic Lens Wearers
Status: COMPLETED
Conditions: Myopia
Interventions: DEVICE: Nelfilcon A contact lens|DEVICE: Narafilcon A contact lens|DEVICE: Etafilcon A contact lens|DEVICE: Omafilcon A contact lens|DEVICE: Hilafilcon B contact lens
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Relative Bioavailability of Four New Formulations of GSK1605786 in Healthy Subjects
Status: COMPLETED
Conditions: Crohn's Disease
Interventions: DRUG: GSK1605786 ChemoCentryx: formulation A|DRUG: GSK1605786 GSK: formulation B|DRUG: GSK1605786 GSK direct-fill: formulation C|DRUG: GSK1605786 GSK modified-process: formulation D|DRUG: GSK1605786 GSK tablet: formulation E
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: [18F]BF3-BPA Injection for PET Imaging Study of Gliomas in the Brain
Status: RECRUITING
Conditions: Cerebral Gliosis|Positron Emission Tomography
Interventions: RADIATION: [18F]BF3-BPA Injection for PET Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Digital Support for Parents of Children in Child Health Care
Status: UNKNOWN
Conditions: Parenting|Children, Only|Health Care Seeking Behavior|Health Knowledge, Attitudes, Practice|Nurse-Patient Relations
Interventions: OTHER: Intervention, digital support
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Platelet Rich Fibrin VS Hyaloronic Acid in Management of Pain After Harvesting a Free Gingival Graft
Status: UNKNOWN
Conditions: Pain, Postoperative
Interventions: DRUG: Topical application of 0.2% hyaluronic acid gel|BIOLOGICAL: Platelet rich fibrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: POWER UP: Participating Online While Exercising to Recover Using Play
Status: SUSPENDED
Conditions: Exercise|Central Nervous System Tumors|Tumors
Interventions: OTHER: Focus Groups|OTHER: Pilot randomized controlled trial
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: DUrable Polymer-based STent CHallenge of Promus Element Versus ReSolute Integrity in an All Comers Population
Status: COMPLETED
Conditions: Acute Coronary Syndrome|Angina Pectoris|Angina, Unstable|Myocardial Infarction|Coronary Artery Disease|Coronary Stenosis|Coronary Restenosis
Interventions: DEVICE: Resolute Integrity (Zotarolimus-eluting stent)|DEVICE: Promus Element (Everolimus-eluting stent)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Advanced Coronary Plaque Morphology Assessment Using Photon-counting Detection and Invasive Coronary Imaging
Status: NOT_YET_RECRUITING
Conditions: Coronary Artery Disease|Coronary Disease|PCI|Stent Restenosis
Interventions: DIAGNOSTIC_TEST: Photon-counting detector computed tomography (PCD-CT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: PENG-block Versus FIB-block in Emergency Room
Status: COMPLETED
Conditions: Pain Relief in Proximal Femoral Fracture
Interventions: PROCEDURE: Regional Anesthesia - Nerve Blocks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Continuous Glucose Monitoring on Glycemic Control and Pregnancy Outcomes in Gestational Diabetes Mellitus
Status: UNKNOWN
Conditions: Gestational Diabetes|Continuous Glucose Monitoring
Interventions: DEVICE: Continuous Glucose Monitoring System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: IN10018 in Combination With Standard Chemotherapy in High-grade Serous Epithelial Ovarian Cancer
Status: RECRUITING
Conditions: Platinum-resistant Ovarian Cancer
Interventions: DRUG: IN10018 in combination with PLD
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Diet and Exercise on Ductal Carcinoma in Situ
Status: COMPLETED
Conditions: Ductal Carcinoma In Situ|Breast Cancer
Interventions: BEHAVIORAL: Active Comparator: Progressive Resistance Training (PRT) and a healthy diet|BEHAVIORAL: Experimental: PRT and a healthy diet, plus weight loss
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Vision Restoration Training in Glaucoma
Status: COMPLETED
Conditions: Glaucoma
Interventions: BEHAVIORAL: vision restoration training|BEHAVIORAL: Discrimination Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Trial of the Elipse™ Intragastric Balloon System for the Treatment of Overweight and Obese Individuals
Status: UNKNOWN
Conditions: Obesity|Overweight
Interventions: DEVICE: Elipse Intragastric Balloon
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Corticosteroids in Reducing Renal Scarring in Acute Pyelonephritis in Children
Status: RECRUITING
Conditions: Urinary Tract Infections in Children|Dexamethasone|Kidney Scarring|Acute Pyelonephritis|Hypertension in Children|Chronic Renal Failure|UTI
Interventions: DRUG: Dexamethasone Oral|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Radiation Therapy, Docetaxel, and Hormone Therapy in High-Risk Locally Advanced Metastasized Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: bicalutamide|DRUG: docetaxel|DRUG: goserelin|RADIATION: intensity-modulated radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Use of Self Retaining Sutures in Open and Laparoscopic Partial Nephrectomy
Status: TERMINATED
Conditions: Kidney Neoplasms
Interventions: DEVICE: Quill knotless tissue-closure device|DEVICE: 2-0 absorbable vicryl suture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Vit D to Treat Asthma in Children: a Randomized, Double-blind, Placebo-controlled Trial
Status: WITHDRAWN
Conditions: Asthma
Interventions: DIETARY_SUPPLEMENT: Vitamin D3 (Cholecalciferol)|DIETARY_SUPPLEMENT: Placebo Drops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Pitavastatin for Hypercholesterolemia
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DRUG: 1PC002|DRUG: Lipitor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prophylactic Antibiotics in Comatose Survivors of Out-of-hospital Cardiac Arrest
Status: COMPLETED
Conditions: Out-of-hospital Cardiac Arrest
Interventions: DRUG: Amoxicillin-Clavulanic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trauma-informed Collaborative Care for Low-income African Americans With PTSD
Status: COMPLETED
Conditions: PTSD
Interventions: OTHER: PTSD Care Management (PCM)|OTHER: Minimally Enhanced Usual Care (MEU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study Of Pembrolizumab In Combination With Trastuzumab-DM1
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: T-DM1|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasound-guided Stellate Ganglion Block for Treatment of Chronic Migraine in Adult
Status: RECRUITING
Conditions: Chronic Migraine
Interventions: PROCEDURE: Stellate Ganglion Block (SGB)|DRUG: standardized drug treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Weekly Oral RAD001 in Combination With Oral Topotecan in Patients With Advanced or Recurrent Endometrial Cancers
Status: COMPLETED
Conditions: Endometrial Cancer
Interventions: DRUG: Topotecan|DRUG: RAD001
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Different Local Anesthetic Dose in Suprascapular and Axillary Blocks in Shoulder Arthroscopies
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: DRUG: Bupivacaine hydrogen chloride (HCl) 0.025 % in 15+15 ML Injection|DRUG: Bupivacaine HCl 0.025 % in 10+10 ML Injection|DRUG: Bupivacaine HCl 0.025 % in 5+5 ML Injection|DRUG: Isotonic solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Two Multiple-dose Regimens of BIA 3-202 on the Pharmacokinetics and Motor Response of Levodopa, and on the Erythrocyte Comt Activity in Parkinson's Disease Patients
Status: COMPLETED
Conditions: Parkinson's Disease (PD)
Interventions: DRUG: Placebo|DRUG: BIA 3-202|DRUG: Comtan®|DRUG: Sinemet®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Active Versus Expectant Management of the Third Stage of Labor
Status: COMPLETED
Conditions: Postpartum Hemorrhage
Interventions: PROCEDURE: Active management of the third stage of labor|PROCEDURE: Expectant management of the third stage of labor|DRUG: Oxytocin and gentle cord traction with fundal massage|DRUG: Oxytocin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Relation Between Blood Concentration of Colchicine and Response to Colchicine Treatment in Gout Flare
Status: TERMINATED
Conditions: Gout Flare
Interventions: DRUG: Colchicine,|DRUG: midazolam,|DRUG: fexofenadine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: New York Blood Center National Cord Blood Program
Status: TERMINATED
Conditions: Leukemia|Lymphoma|Genetic Disease|Severe Aplastic Anemia|Myelodysplasia
Interventions: BIOLOGICAL: Umbilical Cord Blood Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Application of Internet+ Home-based Cardiac Rehabilitation in Atrial Fibrillation Patients After RFCA
Status: UNKNOWN
Conditions: Atrial Fibrillation|Cardiac Rehabilitation
Interventions: BEHAVIORAL: Internet+ home-based cardiac rehabilitation|BEHAVIORAL: Conventional rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of the AERin Medical Vivaer® ARC Stylus for Nasal AirWAY Obstruction
Status: ACTIVE_NOT_RECRUITING
Conditions: Nasal Obstruction
Interventions: DEVICE: Vivaer Stylus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of the Combo Bio-engineered Sirolimus-eluting Stent Versus the Nano Polymer-free Sirolimus-eluting Stent in the Treatment of Patients With de Novo Stenotic Lesions
Status: COMPLETED
Conditions: Coronary Arteriosclerosis
Interventions: DEVICE: OrbusNeich Combo stent™|DEVICE: sirolimus-eluting stent system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Baricitinib in the Treatment of Refractory Axial Spondyloarthritis Patients: A Comparison With Tofacitinib
Status: RECRUITING
Conditions: Spondyloarthritis, Axial
Interventions: DRUG: Baricitinib 2mg|DRUG: Tofacitinib 5 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acceptability, Feasibility and Preliminary Efficacy of CFWP to Treat Clinically Elevated Fatigue in Adults With CF
Status: COMPLETED
Conditions: Cystic Fibrosis|Fatigue
Interventions: OTHER: CF Wellness Program Sessions
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Momelotinib Combined With Trametinib in Adults With Metastatic KRAS-mutated Non-Small Cell Lung Cancer (NSCLC) Who Have Failed Platinum-Based Chemotherapy Preceded by a Dose-finding Lead-in Phase
Status: TERMINATED
Conditions: Relapsed Metastatic KRAS-Mutated Non-Small Cell Lung Cancer
Interventions: DRUG: Momelotinib (MMB)|DRUG: Trametinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate The Efficacy, Safety and Immunogenicity of Inactivated SARS-CoV-2 Vaccines (Vero Cell) in Healthy Population Aged 18 Years Old and Above
Status: COMPLETED
Conditions: COVID-19
Interventions: BIOLOGICAL: Inactivated SARS-CoV-2 Vaccine (Vero cell)|BIOLOGICAL: Inactivated SARS-CoV-2 Vaccine (Vero cell)|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Assess the Short Term Efficacy of Intravenous Ibandronate (Bondronat) in Participants With Metastatic Bone Pain Due to Breast Cancer
Status: COMPLETED
Conditions: Pain; Bone Neoplasms; Neoplasm Metastasis
Interventions: DRUG: Ibandronate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Allogeneic Hematopoietic Cell Transplantation From HLA-matched Donor After Flu-Mel-PTCy Versus Flu-Mel-ATG Reduced-intensity Conditioning
Status: RECRUITING
Conditions: Acute Myeloid Leukemia in Remission|Myelodysplastic Syndromes|Chronic Myeloid Leukemia in Remission|Myeloproliferative Syndrome|Myeloproliferative Disorder|Acute Lymphoid Leukemia in Remission|Multiple Myeloma|Chronic Lymphoid Leukemia|Non Hodgkin Lymphoma|Hodgkin Lymphoma
Interventions: DRUG: Thymoglobulin|DRUG: Melphalan|DRUG: Fludarabine|DRUG: Cyclophosphamid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Circulation Improving Resuscitation Care (CIRC)
Status: COMPLETED
Conditions: Cardiac Arrest|Cardiopulmonary Resuscitation
Interventions: DEVICE: AutoPulse|OTHER: Manual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: IPH5201 and Durvalumab in Patients With Resectable Non-Small Cell Lung Cancer (MATISSE)
Status: RECRUITING
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: IPH5201 + durvalumab + standard chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Interest of Prior Relaxation on the Recordings of the SomatoSensory Evoked Potentials
Status: RECRUITING
Conditions: Relaxation|Somatosensory Evoked Potentials|Patient Experience
Interventions: OTHER: SSEP|OTHER: relaxation session
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Adjuvant Pazopanib in Stage I NSCLC
Status: COMPLETED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: PAZOPANIB|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of TTMPB in Adult Cardiac Surgery
Status: RECRUITING
Conditions: Acute Post Operative Pain
Interventions: DRUG: Transversus thoracic muscle plane block|PROCEDURE: Standard postoperative analgesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Classical Ultrasound Screen and Combined Wearable Display in Interscalene Nerve Blocks
Status: RECRUITING
Conditions: Nerve Block
Interventions: DEVICE: Ultrasound guided smart glasses assisted|DEVICE: Ultrasound guided
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of a Needle-free Local Anesthetic Technique With Traditional Syringe [ Needle Syringe] Technique for the Restoration of Primary Molars and Permanent Molars
Status: COMPLETED
Conditions: Child Behaviour
Interventions: DEVICE: INJEX [Needle less anesthesia]|DEVICE: Syringe Needle [ Traditional technique]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Evaluate Safety and Efficacy of KAM1403 Gel to Treat Radiation Dermatitis
Status: UNKNOWN
Conditions: Radiation Dermatitis
Interventions: DEVICE: KAM1403 Gel|DEVICE: aloevera gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study to Detect V-Raf Murine Sarcoma Viral Oncogene Homolog B1 (BRAF) V600 Mutation on Cell-Free Deoxyribonucleic Acid (cfDNA) From Plasma in Participants With Advanced Melanoma
Status: COMPLETED
Conditions: Metastatic Melanoma
Interventions: DRUG: Cobimetinib|DRUG: Vemurafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Biologic Glue for First Degree Perineal Tears
Status: COMPLETED
Conditions: Grade 1 Perineal Tears
Interventions: DEVICE: 1. Dermabond Topical Skin Adhesive 2-Octyl Cyanoacrylate|PROCEDURE: 3. traditional suturing with vicryl rapid 2X0
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Motor Imagery on Balance in Persons With Multiple Sclerosis
Status: RECRUITING
Conditions: Falls|Motor Imagery|Multiple Sclerosis|Balance|Fatigue
Interventions: OTHER: Motor Imagery as compared to physical practice for balance tasks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Split-face Study Comparing the Cosmetic Efficacy and Tolerability of Two Topical Products in Participants With Moderate Facial Melasma
Status: COMPLETED
Conditions: Melasma
Interventions: OTHER: Lytera 2.0|DRUG: 4% Hydroquinone Topical Cream|OTHER: SkinMedica Facial Cleanser|OTHER: SkinMedica Rejuvenative Moisturizer|OTHER: SkinMedica Essential Defense Mineral Shield Broad Spectrum SPF 35 Sunscreen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Biological Activity of TroVax® Vaccine Given With IL-2 in Renal Cell Carcinoma
Status: COMPLETED
Conditions: Carcinoma, Renal Cell
Interventions: BIOLOGICAL: TroVax|DRUG: IL-2
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of TQB2618 Injection Combined With Toripalimab Injection in Patients With Advanced Melanoma
Status: UNKNOWN
Conditions: Melanoma
Interventions: DRUG: TQB2618 injection|DRUG: Toripalimab injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EfFect of Ablation of Persistent AtriaL Fibrillation on COgNitive Function in Individuals With Mild Cognitive Impairment
Status: RECRUITING
Conditions: Mild Cognitive Impairment|Persistent Atrial Fibrillation
Interventions: PROCEDURE: Atrial fibrillation ablation + antiarrhythmic drugs|DRUG: Antiarrhythmic drug
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Effect of Dietary Supplement on Muscle Mass and Physical Performance for Over 50 Years Old People
Status: COMPLETED
Conditions: Muscle Loss
Interventions: DIETARY_SUPPLEMENT: Dietary supplement|DIETARY_SUPPLEMENT: vitamin B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: App and Body Fat Scale in the Management of Overweight Patients
Status: NOT_YET_RECRUITING
Conditions: Schizophrenia|Bipolar Disorder|Metabolic Syndrome
Interventions: DEVICE: self-monitoring of weight using smart body fat scale with high-precision weighing chip (Huawei Scale 2pro), a mobile phone app (Huawei Health), dietary management, and exercise management.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Psilocybin vs Ketamine for Alcohol Use Disorder
Status: NOT_YET_RECRUITING
Conditions: Alcohol Use Disorder|Alcohol Dependence|Alcohol Abuse
Interventions: DRUG: Psilocybin|DRUG: Ketamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Natural History Study of Monoclonal B Cell Lymphocytosis (MBL), Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL), Lymphoplasmacytic Lymphoma (LPL)/Waldenstrom Macroglobulinemia (WM), and Splenic Marginal Zone Lymphoma (SMZL)
Status: RECRUITING
Conditions: Waldenstrom Macroglobulinemia|Lymphoplasmacytic Lymphoma|Monoclonal B-Cell Lymphocytosis|Small Lymphocytic Lymphoma|CLL (Chronic Lymphocytic Leukemia)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Impact of Detecting Initial and Active Caries Lesions in Primary Teeth
Status: COMPLETED
Conditions: Dental Caries
Interventions: OTHER: Advanced caries lesions detection (no activity assessment)|OTHER: All caries lesions detection (+activity assessment)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Exploratory Study to Evaluate the Efficacy and Safety of CD07223 Gel in Subjects With Acne
Status: COMPLETED
Conditions: Acne
Interventions: DRUG: Epiduo vehicle gel|DRUG: CD07223|DRUG: CD07223|DRUG: Epiduo (adapalene and benzoyl peroxide) 0.1%/2.5% gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intraoperative Radiation Therapy for Locally Advanced or Recurrent Abdomino-pelvic Solid Tumors With the CivaSheet
Status: ACTIVE_NOT_RECRUITING
Conditions: Abdominal Malignancy|Pelvic Malignancy
Interventions: DEVICE: CivaSheet|RADIATION: Brachytherapy|PROCEDURE: surgical resection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Antioxidant Activity of Oral Lutein in Preterm and Term Newborn
Status: COMPLETED
Conditions: Infant, Newborn, Diseases|Other Lipid Storage Disorders
Interventions: DIETARY_SUPPLEMENT: Lutein drops|DIETARY_SUPPLEMENT: Glucose drops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate Preemptive Therapy in Hepatitis C (HCV) Organ Transplant Recipients
Status: RECRUITING
Conditions: Hepatitis C|Kidney Transplant; Complications|Heart Transplant Infection
Interventions: DRUG: Mavyret
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Remote Ischemic Preconditioning of Human Myocardium
Status: COMPLETED
Conditions: Coronary Artery Bypass Graft Triple Vessel|Apoptotic DNA Damage
Interventions: PROCEDURE: Remote ischemic preconditioning|PROCEDURE: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of Biological Response to SARS-COV2 (COVID-19) in Patients With Pre-existing Neurological Disease or Newly Neurological Symptoms (BIO-COCO-NEUROSCIENCES)
Status: COMPLETED
Conditions: Covid19|Neurologic Manifestations|Psychiatric Manifestations
Interventions: OTHER: blood sample
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Transversus Abdominis Plane (TAP) Block for Cesarean Section
Status: COMPLETED
Conditions: Hyperalgesia, Secondary
Interventions: DRUG: Bupivacaine Placebo|DRUG: Clonidine Placebo|DRUG: Bupivacaine|DRUG: Clonidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Benefit of Adding Trastuzumab to Second Line Chemotherapy in Breast Cancer Patients Previously Treated With Trastuzumab
Status: TERMINATED
Conditions: Breast Cancer
Interventions: DRUG: Vinorelbine|DRUG: Capecitabine|DRUG: Trastuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Foot Massage After Open Heart Surgery on Postoperative Pain, Sleep Quality and Mood of Patients
Status: COMPLETED
Conditions: Pain, Postoperative|Sleep Disturbance|Mood|Bypass Complication
Interventions: OTHER: massage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: FOLFOX-4 3months Versus 6 Months and Bevacizumab as Adjuvant Therapy for Patients With Stage II/III Colon Cancer
Status: COMPLETED
Conditions: Colon Cancer
Interventions: DRUG: FOLFOX (Oxaliplatin, 5Fluorouracil, Lederfolin)|DRUG: FOLFOX (Oxaliplatin, 5Fluorouracil, Lederfolin)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Safety, Dose Response and Immunogenicity of the Measles Vaccine MVA mBN85B in Healthy Children Aged 6 Months to 6 Years
Status: COMPLETED
Conditions: Measles
Interventions: BIOLOGICAL: MVA-mBN85B|BIOLOGICAL: MVA-mBN85B|BIOLOGICAL: Rouvax
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Structured Nutrition Education in Type 1 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: BEHAVIORAL: Structured education in carbohydrate counting|BEHAVIORAL: Structured education in healthy food choices and low glycemic index
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Weekly Docetaxel Plus Cisplatin or Oxaliplatin for AGC
Status: UNKNOWN
Conditions: Stomach Neoplasm|Stage IV|Recurrent
Interventions: DRUG: oxaliplatin|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of ODM-109 on Respiratory Function in Patients With Amyotrophic Lateral Sclerosis
Status: COMPLETED
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DRUG: ODM-109|DRUG: Placebo for ODM-109
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Investigation of Sleep Architecture in Ziprasidone-Treated Bipolar Depression
Status: COMPLETED
Conditions: Depression, Bipolar
Interventions: DRUG: ziprasidone hydrochloride|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Development of an Adjustment Assistance Tool Dosage of Fluoroquinolones in a Population Pharmacokinetic Model
Status: COMPLETED
Conditions: Infection
Interventions: DRUG: Patients in intensive care : infection treated with ciprofloxacin IV|DRUG: Osteoarticular infected patients : infection treated with oral ofloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Hemostatic Forceps vs. Bipolar Electrocautery Probes for High-Risk Bleeding Gastroduodenal Ulcers
Status: RECRUITING
Conditions: Gastroduodenal Ulcer
Interventions: DEVICE: Hemostatic Forceps|DEVICE: Bipolar Electrocautery Probes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Vaginal Preparation With Chlorhexidine-alcohol vs. Povidine-iodine vs. Saline
Status: COMPLETED
Conditions: Cesarean Section; Infection|Surgical Site Infection
Interventions: DRUG: Chlorhexidine-alcohol|DRUG: Povidine-iodine|DRUG: Sterile saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of IMU-201 (PD1-Vaxx), a B-Cell Immunotherapy, in Adults With Non-Small Cell Lung Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Non Small Cell Lung Cancer|Non Small Cell Lung Cancer Stage IIIB|Non-small Cell Lung Cancer Stage IV|Squamous Non-small-cell Lung Cancer|Large Cell Carcinoma Lung|Adenocarcinoma Lung
Interventions: BIOLOGICAL: IMU-201 (administered as PD1-Vaxx) - Regimen 1|BIOLOGICAL: IMU-201 (administered as PD1-Vaxx) - Regimen 2|BIOLOGICAL: IMU-201 (administered as PD1-Vaxx) - Regimen 3|DRUG: Atezolizumab|DRUG: Standard of care chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Bepirovirsen in Nucleos(t)Ide Analogue-treated Participants With Chronic Hepatitis B (B-Well 1)
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Hepatitis B|Hepatitis B, Chronic
Interventions: DRUG: Bepirovirsen|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Study inTreatment of Trigeminal Neuralgia
Status: UNKNOWN
Conditions: Trigeminal Neuralgia
Interventions: PROCEDURE: percutaneous radiofrequency trigeminal rhizotomy|PROCEDURE: Microvascular decompression of the trigeminal nerve
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Co-Sér: Serological Analysis and Viral Neutralization in People With a Documented COVID-19 Infection
Status: COMPLETED
Conditions: SARS-CoV Infection|Immune System Disorder
Interventions: DIAGNOSTIC_TEST: Blood sample
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of NN5401 Versus Insulin Glargine, Both Combined With Metformin Treatment, in Subjects With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: insulin degludec/insulin aspart|DRUG: insulin glargine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Transcranial Direct Current Stimulation on Fine Motor Skills in Parkinson's Disease: a Pilot Study
Status: COMPLETED
Conditions: Parkinson's Disease|Transcranial Direct Current Stimulation|Fine Motor Skills|Handwriting
Interventions: DEVICE: transcranial direct current stimulation (tDCS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Intravenous Ferric Carboxymaltose in Pediatric Patients With Iron Deficiency Anemia and Unsatisfactory Response Oral Iron Under Study Protocol 1VIT17044
Status: COMPLETED
Conditions: Iron Deficiency Anemia
Interventions: DRUG: Ferric carboxymaltose
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Surgical / Economic Effect of the Aquamantys System in Blood Management for Aseptic and Septic Revision TKA
Status: COMPLETED
Conditions: Infection of Total Knee Joint Prosthesis|Aseptic Loosening of Prosthetic Joint
Interventions: PROCEDURE: Aquamantys System
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Atorvastatin and Alkali Therapy in Patients With Autosomal Dominant Polycystic Kidney Disease
Status: ENROLLING_BY_INVITATION
Conditions: Autosomal Dominant Polycystic Kidney Disease|Chronic Kidney Diseases
Interventions: DRUG: Atorvastatin 20 Mg Oral Tablet|DRUG: Sodium Bicarbonate 600 Mg Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Subarachnoid Administration of Levobupivacaine for Cesarean Section
Status: UNKNOWN
Conditions: Stillborn Caesarean Section
Interventions: DRUG: Bupivacaine plain|DRUG: Ropivacaine plain|DRUG: Levobupivacaine plain|DRUG: bupivacaine plain +fentanyl|DRUG: ropivacaine plain +. fentanyl|DRUG: Levobupivacaine plain +fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: To Evaluate the Cardiac Safety and PK Following a Single Oral Dose Administration of Pacritinib in Healthy Subjects
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: A: pacritinib|OTHER: B: Placebo|DRUG: C: moxifloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER