pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: International Multicenter Study of the Immunogenicity of Medicinal Product GamEvac-Combi
Status: COMPLETED
Conditions: Ebola Virus Disease|Prevention
Interventions: BIOLOGICAL: GamEvac-Combi (vaccine)|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Transition With a Heart, a Transition Program for Adolescents With Congenital Heart Disease and Parents
Status: COMPLETED
Conditions: Congenital Heart Disease in Adolescence|Transitional Care
Interventions: OTHER: Transition With a Heart (TWAH)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Safety Study of Outdoor and Indoor Mobility in People With Spinal Cord Injury (ROBOtics Spinal Cord Injury EKSO).
Status: TERMINATED
Conditions: Spinal Cord Injury
Interventions: DEVICE: EKSO
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Switching From Tenofovir Disoproxi Fumarate to Tenofovir Alafenamide in Chronic Hepatitis B Patients With Antiviral Resistance
Status: UNKNOWN
Conditions: Hepatitis B|Antiviral Drug Adverse Reaction
Interventions: DRUG: Tenofovir disoproxil fumarate 300mg|DRUG: Tenofovir Alafenamide 25 mg
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Consolidation Treatment With Y90-Ibritumomab Tiuxetan After R-CHOP Induction in High Risk Patients According to Follicular Lymphoma International Prognostic Index (FLIPI) With Follicular Lymphoma
Status: UNKNOWN
Conditions: Follicular Lymphoma
Interventions: DRUG: Y90 Ibritumomab Tiuxetan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: "WB-DCE-MRI" in Multiple Myeloma as an Independent Prognostic Factor for Disease-free Survival
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DEVICE: Whole Body Dynamic Contrast Enhanced MRI (WB-DCE-MRI)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Monocentric Feasibility Study for a New Medical Device for the Treatment of Anal Fissure With Botulinum Toxin
Status: COMPLETED
Conditions: Anal Fissure
Interventions: DEVICE: Anuscope with needles
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Efficacy Study of Topical NEOSH101 to Treat Male Pattern Hair Loss
Status: COMPLETED
Conditions: Androgenetic Alopecia
Interventions: DRUG: tetrapeptide aldehyde proteasome inhibitor (NEOSH101)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Breaking Bad News to Family Members in a Pandemic
Status: RECRUITING
Conditions: Resident Education, Patient Communication, Breaking Bad News to Patients Remotely, Telemedicine
Interventions: OTHER: Education on breaking bad news to family members remotely
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Randomized Short-term Pre-surgical Study to Assess the Effects of Abemaciclib (LY2835219) in Early Breast Cancer Patients
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Abemaciclib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: FOLFOXIRI With or Without Bevacizumab as First-line Treatment for Unresectable Liver-only Metastatic Colorectal Cancer Patients With RAS Mutation-type
Status: UNKNOWN
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: FOLFOXIRI + Bevacizumab|DRUG: FOLFOXIRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Action of Caffeinated and Decaffeinated Espresso on Autonomic Function
Status: TERMINATED
Conditions: Influence of Espresso on Heart Rate Variability
Interventions: OTHER: hab cof with water|OTHER: hab cof with dec espresso|OTHER: hab cof with caf espresso|OTHER: non-hab cof with water|OTHER: non-hab cof with dec espresso|OTHER: non-hab cof with caf espresso
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: PET/CT in Diagnosing Patients With Liver Cancer Undergoing Surgical Resection
Status: COMPLETED
Conditions: Adult Hepatocellular Carcinoma|Localized Resectable Adult Liver Carcinoma
Interventions: DIAGNOSTIC_TEST: Computed Tomography|DRUG: 18F-fluoromethylcholine|DIAGNOSTIC_TEST: Positron Emission Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Subgenual Cingulate Deep Brain STIMulation for Apathetic Behavioral Variant FRONtotemporal Dementia
Status: RECRUITING
Conditions: Frontotemporal Dementia|Deep Brain Stimulation
Interventions: DEVICE: Bilateral subgenual cingulate deep brain stimulation (SGC DBS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigatory Study of Metformin's Pharmacokinetics, Pharmacodynamics and Drug Drug Interactions Classifying the Group by MATE1 Genotype in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Adult
Interventions: DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Folate-Depleted Diet Compared With Folate-Supplemented Diet in Preventing Colorectal Cancer in Patients at High Risk for Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DIETARY_SUPPLEMENT: dietary intervention|DIETARY_SUPPLEMENT: folic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Drug-Drug Interaction Study Assessing Effect of Carbamazepine on PF-07321332 Boosted With Ritonavir
Status: COMPLETED
Conditions: Healthy Participant
Interventions: DRUG: PF-07321332/ritonavir|DRUG: Carbamazepine|DRUG: PF 07321332/ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Trial of pIL-12 Electroporation in Squamous Cell Carcinoma of the Head and Neck (IL12HNSCC)
Status: TERMINATED
Conditions: Head and Neck Squamous Cell Carcinoma
Interventions: BIOLOGICAL: Tavokinogene Telseplasmid (tavo)|DEVICE: OncoSec Medical System (OMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Prophylactic TKI Therapy Post-transplants on Ph+ ALL Undergoing Allo-HSCT With MRD Positive Pre-transplants
Status: UNKNOWN
Conditions: Philadelphia Chromosome Positive Acute Lymphocytic Leukemia|Tyrosine Kinase Inhibitor|Minimal Residual Disease|Allogeneic Hematopoietic Stem Cell Transplantation
Interventions: DRUG: Tyrosine kinase inhibitor (TKIs)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Tiotropium Inhalation Capsules and Oxitropium Metered Dose Inhalator (MDI) in Patients With Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Tiotropium powder inhalation capsules|DRUG: Tersigan®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Perioperative Neurostimulation in Patients Undergoing Whipple Operation (Pancreaticoduodenectomy) on Acute Postsurgical Inflammatory Response [ENSWAPI-trial]
Status: ACTIVE_NOT_RECRUITING
Conditions: Pancreaticoduodenectomy
Interventions: DEVICE: TENS - transcutaneous electrical nerve stimulation|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Contribution of a Virtual Reality Program in the Treatment of Dysmorphophobia for Adolescent Female With Anorexia Nervosa
Status: UNKNOWN
Conditions: Anorexia Nervosa
Interventions: OTHER: self-evaluation of the Body Mass Index|OTHER: Cognitive-behavioral psychotherapies
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gefitinib Combine Radiotherapy as Therapy for Patients With NSCLC Harbouring Sensitive Mutations of EGFR
Status: NOT_YET_RECRUITING
Conditions: Lung Cancer
Interventions: DRUG: Gefitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Duodenal, Ileal or Combined Infusion of Tastants on Food Intake
Status: COMPLETED
Conditions: Obesity
Interventions: DIETARY_SUPPLEMENT: Tastants duodenal|DIETARY_SUPPLEMENT: Tastants ileal|DIETARY_SUPPLEMENT: Placebo duodenal|DIETARY_SUPPLEMENT: Placebo ileal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: SECURE Trial: Stress Echocardiography With Carotid Ultrasound vs Routine CT Coronary Angiography in Chronic Coronary Syndrome for Endpoints
Status: RECRUITING
Conditions: Chronic Coronary Syndrome|Coronary Disease|Coronary Artery Disease
Interventions: DIAGNOSTIC_TEST: Detection of obstructive coronary disease
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Sprix for Postoperative Pain Control Following Gynecologic Surgery
Status: WITHDRAWN
Conditions: Post Operative Pain Control|Narcotic Use|Pelvic Organ Prolapse|Urinary Incontinence , Stress|Surgery
Interventions: DRUG: Sprix
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Therapy With Entinostat and Pembrolizumab in Relapsed and Refractory Lymphomas
Status: ACTIVE_NOT_RECRUITING
Conditions: Lymphoma|Relapsed|Refractory
Interventions: DRUG: Entinostat|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study Assessing Intra-Metastasis Administration of Autologous KLH-pulsed Dendritic Cells With Tumoral Radiation Therapy in Patients With Metastatic Pancreatic Carcinoma
Status: TERMINATED
Conditions: Metastatic Pancreatic Carcinoma
Interventions: RADIATION: tumoral irradiation|BIOLOGICAL: Dendritic cell vaccination
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence of the Tablet and Liquid-Filled Capsule Forms of MK0974 (0974-042)
Status: COMPLETED
Conditions: Migraine
Interventions: DRUG: MK0974 tablet|DRUG: Comparator: MK0974 liquid filled capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Methadone, Morphine, or Oxycodone in Treating Pain in Patients With Cancer
Status: TERMINATED
Conditions: Brain and Central Nervous System Tumors|Chronic Myeloproliferative Disorders|Leukemia|Lymphoma|Lymphoproliferative Disorder|Multiple Myeloma and Plasma Cell Neoplasm|Myelodysplastic Syndromes|Myelodysplastic/Myeloproliferative Neoplasms|Pain|Precancerous Condition|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: methadone hydrochloride|DRUG: morphine sulfate|DRUG: oxycodone hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Cranial Stimulation for Chemotherapy Symptoms in Breast Cancer
Status: COMPLETED
Conditions: Anxiety Disorder|Breast Cancer|Depression|Fatigue|Pain|Sleep Disorders
Interventions: PROCEDURE: energy-based therapy|PROCEDURE: sham intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: ALFAURUS : A DB Randomized Parallel Group Study of Alfuzosin 10mg OD vs Placebo in the Management of AUR in Patients With a 1st Episode Due to BPH
Status: COMPLETED
Conditions: Prostatic Hyperplasia|Acute Urinary Retention
Interventions: DRUG: Alfuzosin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Non-invasive Method for Predicting the Presence of Gastroesophageal Varices in Patients With Cirrhosis-a Prospective, Multicenter Trial
Status: RECRUITING
Conditions: Gastroesophageal Varices; Decompensation Event
Interventions: OTHER: Esophagogastroduodenoscopies
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Influence of Cancer Stem-cells on Risk of Relapse in Patients Harboring Adenocarcinoma and Squamous Cell Carcinoma of the Lung
Status: COMPLETED
Conditions: Lung Cancer, Nonsmall Cell|Relapse/Recurrence|CSC
Interventions: GENETIC: Exposure to lung cancer stem cells
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study to Evaluate Interferon Gamma (IFNγ) and Other Inflammatory Mediators in Patients With Malignancy-Associated Hemophagocytic Lymphohistiocytosis (M-HLH)
Status: COMPLETED
Conditions: Hemophagocytic Lymphohistiocytosis
Interventions: OTHER: Blood Draws|OTHER: Data Collection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Neoadjuvant PD-1 Blockade for Elderly Esophageal Squamous Cell Carcinoma (BLESS)
Status: RECRUITING
Conditions: Esophageal Cancer
Interventions: DRUG: neoadjuvant anti-PD-1|DRUG: neoadjuvant anti-PD-1 with LDRT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I Clinical Trials Investigating the Potential Efficacy of Axitinib in Patients With a BRCA 1/2 Mutations
Status: ENROLLING_BY_INVITATION
Conditions: Breast Cancer|Ovarian Cancer|Breast Neoplasms|Ovarian Neoplasms|BRCA Mutation|HER2-positive Breast Cancer|HER2-negative Breast Cancer|HER-2 Protein Overexpression
Interventions: DRUG: Axitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cognitive Stimulation Therapy
Status: COMPLETED
Conditions: Alzheimer Disease 10|Dementia|Apathy|Anxiety|Loneliness
Interventions: BEHAVIORAL: Cognitive Stimulation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Probiotic Intervention on Gut Microbiota and Cognitive Functioning in Older Adults With a Mild Cognitive Impairment
Status: RECRUITING
Conditions: Mild Cognitive Impairment
Interventions: DIETARY_SUPPLEMENT: Experimental: The probiotic drink study group|DIETARY_SUPPLEMENT: Placebo Comparator: The placebo drink study group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Increased Sensitivity to Pain Caused by Opioids in People Who Have Abused Prescription Opioids
Status: TERMINATED
Conditions: Chronic Pain
Interventions: DRUG: Pregabalin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Paclitaxel-eluting Balloon Angioplasty With Provisional Use of Nitinol Stent Versus Systematic Implantation of Paclitaxel-eluting Stent for the Treatment of Femoropopliteal de Novo Lesions
Status: UNKNOWN
Conditions: Peripheral Artery Disease
Interventions: DEVICE: PEB|DEVICE: PES
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Drug Activity in Women With Breast Cancer and no Previous Herceptin Treatment
Status: TERMINATED
Conditions: Breast Neoplasm
Interventions: DRUG: Drug-AZD8931|DRUG: Drug-Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study With TMC125 in Human Immunodeficiency Virus (HIV) Type 1 Infected Patients, Who Were Treated With TMC125 Arm in a Sponsor-Selected TMC125 Study
Status: COMPLETED
Conditions: Human Immunodeficiency Virus Type 1
Interventions: DRUG: Etravirine (ETR)|DRUG: Nucleotide reverse transcriptase inhibitors (NRTIs)|DRUG: Protease inhibitors (PIs)|DRUG: Enfuvirtide (ENF)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adjunctive Treatment With L-methylfolate for Treatment-Resistant Generalized Anxiety Disorder: a Pilot Study
Status: NOT_YET_RECRUITING
Conditions: Generalized Anxiety Disorder
Interventions: DRUG: L-methylfolate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study of Genetically Targeted Enzyme Replacement Therapy for Advanced Heart Failure
Status: COMPLETED
Conditions: Ischemic Cardiomyopathy|Non-ischemic Cardiomyopathy|Heart Failure|Cardiomyopathies
Interventions: GENETIC: AAV1/SERCA2a (MYDICAR)|GENETIC: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Variable Intensive Early Walking Post-Stroke - 2 (VIEWS-2)
Status: RECRUITING
Conditions: Stroke
Interventions: BEHAVIORAL: High-intensity, task-specific (i.e., walking) interventions|BEHAVIORAL: High-intensity, non-specific physical therapy interventions|BEHAVIORAL: Low-intensity, task-specific physical therapy interventions|BEHAVIORAL: Low-intensity, non-specific physical therapy interventions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Home-based Program in Improving Sitting Balance and Upper Limb Functions in Patients With Stroke
Status: COMPLETED
Conditions: Stroke
Interventions: BEHAVIORAL: electrical stimulation with exercises|BEHAVIORAL: placebo stimulation with exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Weight Loss Interventions to Reduce Cancer Progression in Prostate Cancer Patients Under Active Surveillance
Status: RECRUITING
Conditions: Prostate Carcinoma
Interventions: PROCEDURE: Biospecimen Collection|OTHER: Dietary Intervention|OTHER: Dietary Intervention|BEHAVIORAL: Fasting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effects of Complementary Feeding on Infant Growth and Gut Health
Status: RECRUITING
Conditions: Gut Microbiome|Linear Growth
Interventions: OTHER: Baby Foods - Meat|OTHER: Baby Foods - Dairy|OTHER: Baby Foods - Plant|OTHER: Foods from the home
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Evaluate the Efficacy and Safety of Intravitreal KSI-301 in Non-proliferative Diabetic Retinopathy (NPDR)
Status: TERMINATED
Conditions: Non-proliferative Diabetic Retinopathy
Interventions: DRUG: KSI-301|OTHER: Sham injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: GLP-1 CellBeads® for the Treatment of Stroke Patients With Space-occupying Intracerebral Hemorrhage
Status: TERMINATED
Conditions: Intracerebral Hemorrhage (ICH)
Interventions: DRUG: GLP-1 CellBeads
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The RESTORE-SIRIO Randomized Controlled Trial
Status: WITHDRAWN
Conditions: Percutaneous Coronary Intervention|No-reflow Phenomen|Acute ST-segment Elevation Myocardial Infarction
Interventions: OTHER: intracoronary epinephrine|OTHER: no intracoronary epinephrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: A Study to Determine the Bioequivalence of SCH 900068 Compared to Marketed Products (Protocol No. P07551)
Status: COMPLETED
Conditions: Hyperlipidemia
Interventions: DRUG: Ezetimibe|DRUG: Ezetimibe/atorvastatin 10mg/10mg FDC|DRUG: Atorvastatin 10mg|DRUG: Atorvastatin 80mg|DRUG: Ezetimibe/atorvastatin 10mg/80mg FDC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trans Sodium Crocetinate (TSC) Study of Intra-tumoral Oxygen Concentration, Safety, and Pharmacokinetics in Patients With High Grade Glioma
Status: TERMINATED
Conditions: High Grade Glioma
Interventions: DRUG: Trans Sodium Crocetinate (TSC)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Safety of 2 Doses of Tiotropium Via Respimat Compared to Placebo in Adolescents With Moderate Persistent Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: tiotropium Respimat low dose|DRUG: placebo Respimat|DRUG: tiotropium Respimat high dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Dose-ranging Study of APD405 in Post-operative Nausea and Vomiting (PONV)
Status: COMPLETED
Conditions: Postoperative Nausea and Vomiting
Interventions: DRUG: APD405|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Subcutaneous Closed-Suction Drainage Affects Surgical Wounds Healing in Lower Gastrointestinal Open Surgery: a Randomized Controlled Study
Status: UNKNOWN
Conditions: All Diseases That Require Gastrointestinal Open Surgery
Interventions: DEVICE: Subcutaneous closed-suction drainage device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: APX005M and Doxorubicin in Advanced Sarcoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Soft Tissue Sarcoma
Interventions: DRUG: Doxorubicin|DRUG: APX005M
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study on Probiotic Formula in Autistic Children
Status: NOT_YET_RECRUITING
Conditions: Autism Spectrum Disorder
Interventions: OTHER: Probiotic formula capsule|OTHER: placebo capsule|OTHER: FMT capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Long Protocol and Freeze All Embryos vs Antagonist Protocol With Fresh Embryo Transfer in PCOS Patients Undergoing ICSI
Status: COMPLETED
Conditions: Invitro Fertilization
Interventions: DRUG: Triptorelin|DRUG: cetrorelix|DRUG: Recombinant Follicle Stimulating Hormone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Moxifloxacin/Prednisolone in Prevention of Post Surgery Inflammation
Status: UNKNOWN
Conditions: Eye Infection/Inflammation Other
Interventions: DRUG: moxifloxacin 0,5% + prednisolone 1%|DRUG: moxifloxacin/prednisolone combination
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Efficacy and Safety of Microfracture and Modified Microfracture
Status: UNKNOWN
Conditions: Defect of Articular Cartilage|Osteoarthritis|Traumatic Arthritis
Interventions: PROCEDURE: Microfracture|DEVICE: CartiFill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: In Situ Remineralisation Response of Different Artificial Caries-like Enamel Lesions to Home-care and Professional Fluoride Treatments
Status: COMPLETED
Conditions: Dental Caries
Interventions: OTHER: Application of fluoride varnish (22600 ppm F, Duraphat) at the begining of the study|OTHER: Application of fluoride toothpaste (1500 ppm F, Crest) twice a day for 3 days of the study|OTHER: Application of placebo toothpaste (0 ppm F, Ice Fresh) twice a day for 3 days of the study
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Tolcapone in Obsessive Compulsive Disorder
Status: COMPLETED
Conditions: Obsessive-Compulsive Disorder
Interventions: DRUG: Tolcapone 200 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rehabilitation of Patients With COPD Using Electrical Muscle Stimulation
Status: COMPLETED
Conditions: COPD
Interventions: PROCEDURE: Transcutaneous Electrical Muscle Stimulation (TCEMS)|OTHER: Sham TCEMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness and Safety of Partition Multi-point Defocused Myopia Management Spectacle Lens in Myopia Control
Status: ACTIVE_NOT_RECRUITING
Conditions: Myopia
Interventions: OTHER: Partition defocus myopia management spectacle lens|OTHER: Spectacle lenses with aspherical lenslets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Hemodynamic Effects of Stored Blood Transfusion in Intensive Care Patients
Status: TERMINATED
Conditions: Pulmonary Hypertension
Interventions: BIOLOGICAL: Blood transfusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects on Pain of Acupressure and Foot Reflexology Before Heel Lancing in Newborns
Status: COMPLETED
Conditions: Interventions Pain
Interventions: OTHER: Acupressure methods|OTHER: Foot Reflexology Methods|OTHER: Control Grup
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparison Between Effect of Enoxaparin and Clopidogrel on Improving Pregnancy Rate in ICSI
Status: UNKNOWN
Conditions: Female , Infertility
Interventions: DRUG: clopidogrel|DRUG: enoxaparin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Posterior Compression Distraction Reduction （CDR）Technique in the Treatment of BI-AAD
Status: UNKNOWN
Conditions: Basilar Invagination Associated With Atlantoaxial Dislocation
Interventions: PROCEDURE: Posterior Approach Compression Distraction Reduction
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II Trial of Oxaliplatin in Combination With S-1(SOX) in Patients With Recurrent or Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Neoplasms
Interventions: DRUG: TS-1 and Eloxatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of XL184 (Cabozantinib) in Advanced Medullary Thyroid Cancer
Status: COMPLETED
Conditions: Thyroid Cancer
Interventions: DRUG: XL184|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Exploratory Safety and Immunogenicity Study of HPV16+ Immunotherapy VB10.16 in Women With HSIL; CIN 2/3)
Status: COMPLETED
Conditions: High Grade Cervical Intraepithelial Neoplasia
Interventions: BIOLOGICAL: VB10.16 Immunotherapy (DNA vaccine)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Diagnosis and Treatment System of Transesophageal Echocardiography in ICU
Status: UNKNOWN
Conditions: Critically Ill
Interventions: DIAGNOSTIC_TEST: Transesophageal echocardiography
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SCREENING
Clinical trial: Open or Laparoscopic Mesolectal Excision in Low Rectum Cancer
Status: COMPLETED
Conditions: Rectal Cancer
Interventions: PROCEDURE: laparoscopic-assited excision of mesorectum with pelvic lymph nodes excision
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Atorvastatin and Pioglitazone on Carotid Atherosclerosis With the Use of Positron Emission Tomography-computed Tomography (PET-CT)
Status: TERMINATED
Conditions: Atherosclerosis|Coronary Artery Disease
Interventions: DRUG: Atorvastatin 20mg|DRUG: Atorvastatin 20 mg + Pioglitazone 30 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Dutasteride Five 0.1 mg and One 0.5 mg Soft Gelatin Capsules in Healthy Male Volunteers
Status: COMPLETED
Conditions: Alopecia
Interventions: DRUG: GI198745 0.1 mg|DRUG: GI198745 0.5 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Study on the Esketamine in the Treatment of Postherpetic Neuralgia
Status: UNKNOWN
Conditions: Postherpetic Neuralgia|Esketamine
Interventions: DRUG: esketamine|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pemetrexed Disodium and Cisplatin Followed By Surgery and Radiation Therapy in Treating Patients With Malignant Pleural Mesothelioma
Status: COMPLETED
Conditions: Malignant Mesothelioma
Interventions: DRUG: cisplatin|DRUG: pemetrexed disodium|PROCEDURE: adjuvant therapy|PROCEDURE: conventional surgery|PROCEDURE: neoadjuvant therapy|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Evaluate the Maximum Tolerated Dose of BAY87-2243 in Patients With Advanced Malignancies
Status: TERMINATED
Conditions: Neoplasms
Interventions: DRUG: BAY87-2243
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cardiovascular Risk Reduction in Atrial Fibrillation Trial
Status: RECRUITING
Conditions: Atrial Fibrillation|Hypertension
Interventions: DRUG: Intensive BP Control|DRUG: Standard BP Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sorafenib Concomitantly Used With TACE (Transarterial Chemoembolization) in uHCC (Unresectable Hepatocellular Carcinoma) Patients in China
Status: COMPLETED
Conditions: Carcinoma, Hepatocellular
Interventions: DRUG: Sorafenib (Nexavar, BAY43-9006)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: New 3D Printed Wrist Orthosis
Status: RECRUITING
Conditions: Carpal Tunnel Syndrome|Ulnar Nerve Injury|Rhizarthrosis|Tendinopathy, Thumb|Tenosynovitis de Quervain|Hand Disease
Interventions: DEVICE: Wrist and Thumb orthosis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Neoadjuvant Therapy for the Treatment of Patients With Locally Advanced Esophageal Squamous Cell Carcinoma
Status: RECRUITING
Conditions: Neoadjuvant Therapy|Esophageal Squamous Cell Carcinoma
Interventions: DRUG: anlotinib|RADIATION: Thoracic radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing the Prognosis of Lactate-directed and Goal-directed Therapy in Hyperthermic Intraperitoneal Chemotherapy.
Status: WITHDRAWN
Conditions: Organ Failure, Multiple
Interventions: OTHER: Lactate-directed therapy|OTHER: Goal-directed therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective Observational Trial to Evaluate Quality of Life After Neoadjuvant Radiation or Chemoradiation Followed by Surgery in Patients With Rectal Cancer
Status: RECRUITING
Conditions: Rectal Cancer|Quality of Life|Radiation Therapy|Chemoradiation
Interventions: OTHER: EORTC QLQ C30|OTHER: EORTC QLQ CR29
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Intracapsular Injection of Terlipressin Versus Carbitocin on Hemoglobin and Blood Loss During Laparoscopic Myomectomy Operations
Status: RECRUITING
Conditions: Myoma
Interventions: DRUG: Terlipressin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: VX-853 in Treating Patients With Solid Tumors Who Are Receiving Liposomal Doxorubicin
Status: COMPLETED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: VX-853|DRUG: pegylated liposomal doxorubicin hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Moviprep® Versus Fleet Phospho-Soda® (Golden Standard): A Study That Compared Two Laxatives on Patients Undergoing Colo-Rectal Cleansing Prior to an Abdominal Operation
Status: COMPLETED
Conditions: Colorectal Cleansing Prior Operation
Interventions: DRUG: Moviprep®|DRUG: Fleet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Changing Trunk Muscle Activation in Patients With Recurrent Low Back Pain in Remission
Status: RECRUITING
Conditions: Recurrent Low Back Pain|Remission
Interventions: BEHAVIORAL: Specific sensorimotor control training|BEHAVIORAL: Aspecific extension training|BEHAVIORAL: Fascia training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Electroacupuncture Treatment for Those With End Stage Knee Osteoarthritis on a Total Knee Arthroplasty Waitlist
Status: WITHDRAWN
Conditions: Knee Osteoarthritis
Interventions: OTHER: Electroacupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: 7T MRI Scan for the Early Detection of Melanoma Brain Metastases
Status: RECRUITING
Conditions: Clinical Stage IV Cutaneous Melanoma AJCC v8|Metastatic Malignant Neoplasm in the Brain|Metastatic Melanoma|Pathologic Stage IV Cutaneous Melanoma AJCC v8
Interventions: DIAGNOSTIC_TEST: Magnetic Resonance Imaging using 7 Tesla MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Entecavir for Biological Agents Associated HBV Reactivation in Inflammatory Arthritis Patients
Status: UNKNOWN
Conditions: Rheumatoid Arthritis|Hepatitis B Reactivation|Exposure to Hepatitis B Virus
Interventions: DRUG: Entecavir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Antibiotics Usage in Pediatric Orthopaedic Percutaneous Surgery (APOPS)
Status: COMPLETED
Conditions: Supracondylar Humerus Fracture|Post Operative Wound Infection
Interventions: DRUG: Cefazolin|DRUG: Clindamycin|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Safety and Efficacy of Inactivated Varicella-zoster Vaccine (VZV) as a Preventative Treatment for Herpes Zoster (HZ) and HZ-related Complications in Adult Participants With Solid Tumor or Hematologic Malignancy (V212-011)
Status: COMPLETED
Conditions: Herpes Zoster
Interventions: BIOLOGICAL: V212|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate and Study Drug Levels in Blood Plasma When Giving High Doses of GSK189075 to Healthy Volunteers
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus|Diabetes Mellitus, Type 2
Interventions: DRUG: GSK189075
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Virtual Task in Amyotrophic Lateral Sclerosis
Status: COMPLETED
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DEVICE: Acquisition on TouchScreen|DEVICE: Acquisition on Kinect|DEVICE: Acquisition on LeapMotion|DEVICE: Acquisition on TouchScreen Control Group|DEVICE: Acquisition on Kinect Control Group|DEVICE: Acquisition on LeapMotion Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Volar Carbon Plate Effects on Procedure Time
Status: COMPLETED
Conditions: Radiation Exposure|Surgery|Radius Distal Fracture
Interventions: PROCEDURE: The Effect of Volar Carbon Plate Applications on Radiation Exposure and Procedure Time in Intra-articular Radius Distal End Fractures
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: SIGNAL:Identifying Behavioral Anomalies Using Smartphones to Improve Cancer Care
Status: WITHDRAWN
Conditions: Ovarian Cancer|Fallopian Tube Cancer|Primary Peritoneal Carcinoma|Uterine Cancer|Cervical Cancer|Gynecologic Cancer
Interventions: BEHAVIORAL: SIGNAL
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Hemodynamic Indices Predictive of a Beneficial Response to Fluid Expansion in Case of Hemodynamic Failure After Cardiac Surgery With Altered Preoperative Ejection Fraction (LVEF≤45%)
Status: COMPLETED
Conditions: Ventricular Dysfunction
Interventions: PROCEDURE: cardiac surgery for ventricular dysfunction
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Super-selective Intra-arterial Cerebral Infusion of Trastuzumab for the Treatment of Cerebral Metastases of HER2/Neu Positive Breast Cancer
Status: TERMINATED
Conditions: Neoplasm Metastasis
Interventions: DRUG: Intra-arterial Cerebral Infusion of Trastuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neurodevelopment and Neuroimaging in Parenterally-fed Infants and Young Children
Status: COMPLETED
Conditions: Parenteral Nutrition|Necrotizing Enterocolitis|Digestive System Abnormalities|Cholestasis
Interventions: DIETARY_SUPPLEMENT: Remove Mn from PN if evidence of increased brain Mn on MRI
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Quantitative in Vivo Biomarkers of Oxidative Stress in Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes|Oxidative Stress
Interventions: BIOLOGICAL: ascorbic acid (Vitamin C)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Safety of and Immune Response to an HIV Vaccine (VRC-HIVDNA009-00-VP) Administered With Interleukin-2/Immunoglobulin (IL-2/Ig) DNA Adjuvant in Uninfected Adults
Status: COMPLETED
Conditions: HIV Infections
Interventions: BIOLOGICAL: VRC-HIVDNA009-00-VP (Gag-Pol-Nef-multiclade-Env) with adjuvant VRC-ADJDNA004-IL2-VP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Effect of Vinyasa Yoga on Frailty and Anthropometric Measurements in Elderly Individuals
Status: COMPLETED
Conditions: Geriatrics|Yoga|Complementary Therapies|Nursing Caries
Interventions: OTHER: Yoga|OTHER: Standard exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Evaluate Topically Applied SXR1096 Cream in Patients With Netherton Syndrome
Status: UNKNOWN
Conditions: Netherton Syndrome
Interventions: DRUG: SXR1096 cream|DRUG: Placebo cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Developing a Trauma-focused Intervention for Older Adults Living With HIV
Status: RECRUITING
Conditions: Trauma|Hiv|Aging
Interventions: BEHAVIORAL: CoSHA (Coping with childhood Sexual Abuse, HIV, and Aging)|BEHAVIORAL: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Pulsed 1064nm Nd:YAG in the Treatment of Verruca Vulgaris Versus Conventional Therapy With Liquid Nitrogen Cryotherapy
Status: TERMINATED
Conditions: Verruca Vulgaris
Interventions: PROCEDURE: Liquid Nitrogen Cryotherapy|PROCEDURE: Pulsed 1064nm Nd:YAG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility Study of CDDP + CPT-11 + PSK for Extensive-Stage Disease (ED) Small Cell Lung Cancer
Status: UNKNOWN
Conditions: Small Cell Lung Cancer
Interventions: DRUG: Irinotecan hydrochloride|DRUG: Cisplatin|DRUG: Krestin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of XPO-1 Inhibitors Plus CAR-T Cells in Relapsed Refractory B-cell Non-Hodgkin's Lymphoma
Status: UNKNOWN
Conditions: Relapsed/Refractory B-cell Non-Hodgkin's Lymphoma
Interventions: DRUG: Selinexor|DRUG: Flu|DRUG: CTX|DRUG: CAR-T
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of B-Type Natrieutic Peptide (BNP) Levels in Patients With Congenital Heart Disease(BNP)
Status: COMPLETED
Conditions: Congenital Heart Disease|Cardiovascular Disease
Interventions: PROCEDURE: Six minute walk test|BEHAVIORAL: Minnesota Living with Heart Failure Questionnaire
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Perineural Methylene Blue Infusion in Lower Limb Amputation Surgery
Status: RECRUITING
Conditions: Perineural|Methylene Blue|Lower Limb Amputation
Interventions: DRUG: Bupivacaine methylene blue|DRUG: bupivacaine saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of the Pharmacokinetics, Safety and Tolerability of Single Doses of VR647 Inhalation Suspension Administered Using the VR647 Inhalation System in Children With Wheezing, Reactive Airway Disease or Mild Asthma
Status: COMPLETED
Conditions: Wheezing|Reactive Airway Disease|Mild Asthma
Interventions: COMBINATION_PRODUCT: VR647 Inhalation Suspension (budesonide) 1 mg/2 mL delivered by the VR647 Inhalation System|COMBINATION_PRODUCT: 1 mg/2 mL Pulmicort Respules delivered by a conventional jet nebulizer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Vitamins Among Children of HIV-infected Women
Status: COMPLETED
Conditions: HIV Infections|Pregnancy Complications
Interventions: DRUG: Multivitamins - vitamins B complex, C and E|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Sodium-Glucose Cotransporter-2 Inhibitors: A Potential Novel Treatment for Epilepsy
Status: UNKNOWN
Conditions: Epilepsy
Interventions: DRUG: Empagliflozin 25 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Noninvasive Brain Stimulation on Memory in Individuals With Mild Cognitive Impairment and History of Brain Injury
Status: ACTIVE_NOT_RECRUITING
Conditions: Amnestic Mild Cognitive Impairment|Traumatic Brain Injury|Mild Traumatic Brain Injury
Interventions: DEVICE: High Definition Transcranial Direct Current Stimulation|DEVICE: Sham HD-tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT