pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Treatment of Fatigue With Methylphenidate, Modafinil and Amantadine in Multiple Sclerosis
Status: COMPLETED
Conditions: Fatigue in Multiple Sclerosis
Interventions: DRUG: Amantadine|DRUG: Modafinil|DRUG: Methylphenidate|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Increase HIV Testing Among Truck Drivers and Female Sex Workers in Kenya Through Offering HIV Self-Testing
Status: COMPLETED
Conditions: HIV Testing
Interventions: BEHAVIORAL: Intervention|BEHAVIORAL: Enhanced Standard of Care|BEHAVIORAL: Traditional Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SCREENING
Clinical trial: Comparison of Subjective Outcomes and Changes of Ultrasonographic Morphology of Median Nerves of Mini-open and Endoscopic Carpal Tunnel Release in Patients With Idiopathic Carpal Tunnel Syndrome
Status: COMPLETED
Conditions: Idiopathic Carpal Tunnel Syndrome
Interventions: PROCEDURE: Mini-incision carpal tunnel release|PROCEDURE: Endoscopic carpal tunnel release
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Single Daily Dose of Ceftriaxone and Metronidazole for Treatment of Complicated Appendicitis in Children
Status: COMPLETED
Conditions: Complicated Appendicitis
Interventions: DRUG: ceftriaxone, metronidazole/ampicillin, gentamicin, and metronidazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunization of Children Previously Primed With GSK Pneumococcal Vaccine GSK1024850A and of Unprimed Children in Mali
Status: COMPLETED
Conditions: Infections, Streptococcal
Interventions: BIOLOGICAL: Pneumococcal vaccine GSK1024850A
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effects of Iloprost on Hypoxic Pulmonary Vasoconstriction and Exercise Capacity at High Altitude
Status: UNKNOWN
Conditions: Hypoxic Pulmonary Vasoconstriction
Interventions: DRUG: iloprost
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of CPAP on Abnormal Gastroesophageal Reflux and Lung Inflammation in IPF
Status: RECRUITING
Conditions: Idiopathic Pulmonary Fibrosis|Obstructive Sleep Apnea|Gastro Esophageal Reflux
Interventions: DEVICE: Positive Airway Pressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Micro-Clinic Obesity and Metabolic Risk Prevention Program
Status: COMPLETED
Conditions: Diabetes Mellitus, Type II|Heart Disease|Obesity|Hypertension|Dyslipidemia
Interventions: BEHAVIORAL: Microclinic Diabetes Education Program|BEHAVIORAL: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: IDEAL: Intended to Determine the Effects of Seladelpar on Normalization of Alkaline Phosphatase Levels in Subjects With Primary Biliary Cholangitis (PBC) and an Incomplete Response or Intolerance to Ursodeoxycholic Acid (UDCA)
Status: RECRUITING
Conditions: Primary Biliary Cholangitis
Interventions: DRUG: Seladelpar 10 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: PET/CT Guided Robotic Arm-assisted Pain Palliation in Chronic Nociceptive Low Backache
Status: UNKNOWN
Conditions: Chronic Low-back Pain|Nociceptive Pain
Interventions: PROCEDURE: F-18 sodium fluoride PET/CT guided robotic arm assisted injection of combination of local anesthetic and steroids
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Pemafibrate in Patients With Nonalcoholic Fatty Liver Disease (NAFLD)
Status: COMPLETED
Conditions: Non-Alcoholic Fatty Liver Disease
Interventions: DRUG: K-877|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Baricitinib in Participants From 1 Year to Less Than 18 Years Old With Juvenile Idiopathic Arthritis
Status: RECRUITING
Conditions: Juvenile Idiopathic Arthritis
Interventions: DRUG: Baricitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transepidermal Application of Metilaminolevulinate in Daylight PDT in the Treatment of Photodamaged Skin
Status: COMPLETED
Conditions: Skin Diseases
Interventions: PROCEDURE: Group I (Standard DL-PDT)|PROCEDURE: Group II (DL-PDT with microneedles)|PROCEDURE: Group III (DL-PDT with CO2 laser)|PROCEDURE: Group IV (DL-PDT with microdermabrasion)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sipuleucel-T, CT-011, and Cyclophosphamide for Advanced Prostate Cancer
Status: TERMINATED
Conditions: Prostatic Neoplasms
Interventions: DRUG: CT-011 (Anti-PD1 Antibody)|OTHER: Sipuleucel-T (Provenge)|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exploration of Adaptive Antitumoral Immune Cells Through Lymphapheresis in Cancer Patients : ALCYTA
Status: RECRUITING
Conditions: Cancer|Immune System or Toxicities Suspected
Interventions: OTHER: blood sample|OTHER: blood sample
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Theralux Extracorporeal Photochemotherapy (ECP) in Patients With Extensive Chronic Graft Versus Host Disease (GvHD)
Status: COMPLETED
Conditions: Graft vs Host Disease
Interventions: BIOLOGICAL: Theralux extracorporeal photochemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Priority-Matching Correction Technique in Degenerative Lumbar Scoliosis
Status: NOT_YET_RECRUITING
Conditions: Degenerative Lumbar Disease|Scoliosis|Degenerative Scoliosis
Interventions: PROCEDURE: Priority-matching correction technique in DLS|PROCEDURE: Traditional correction technique in DLS
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sleep Apnea in Type 1 Diabetes
Status: COMPLETED
Conditions: Type 1 Diabetes, Sleep Apnea Syndrome
Interventions: OTHER: Polysomnography|OTHER: Evaluation of the autonomous nervous system|OTHER: Clinical examination of the sleep|OTHER: Clinical examination of diabetology|OTHER: Biological dosages|OTHER: Electrocardiogram (ECG)|OTHER: Carotid echography|OTHER: Blood pressure
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Blood Flow Restriction Exercise in Patients With Pancreatic, Biliary Tract, and Liver Cancer (PREV-Ex)
Status: RECRUITING
Conditions: Pancreatic Cancer|Biliary Tract Cancer|Liver Cancer
Interventions: OTHER: Physical exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Mometasone and Markers of Airway Inflammation
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Placebo|DRUG: Mometasone Furoate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Recombinant Human Keratinocyte Growth Factor to Reduce Oral Mucositis in Hematologic Malignancy Patients Undergoing Peripheral Blood Stem Cell Transplantation After Radiation and High-dose Chemotherapy
Status: COMPLETED
Conditions: Stomatitis
Interventions: DRUG: Recombinant Human Keratinocyte Growth Factor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Peri-operative Use of a Pain Injection in Pediatric Patients With Cerebral Palsy
Status: COMPLETED
Conditions: Cerebral Palsy|Hip Dysplasia|Pain, Postoperative
Interventions: DRUG: Ropivacaine injection|DRUG: normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Tislelizumab Combined With Chemotherapy in the Cross-line Treatment of First-line Resistant Advanced Gastric Cancer
Status: NOT_YET_RECRUITING
Conditions: Gastric Cancer
Interventions: DRUG: Tislelizumab|DRUG: 5Fu|DRUG: Paclitaxel injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Brief Online Mindfulness Intervention: An RCT Protocol
Status: RECRUITING
Conditions: Stress|Anxiety|Depression
Interventions: BEHAVIORAL: A brief (14-day) online mindfulness intervention|BEHAVIORAL: Psychoeducation online
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Trail Evaluating Apatinib With IMRT for Inoperable or Iodine Refractory Thyroid Cancer
Status: UNKNOWN
Conditions: Thyroid Cancer
Interventions: DRUG: Apatinib|RADIATION: Intensity modulated radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ABT-888 With Modified FOLFOX6 in Patients With Metastatic Pancreatic Cancer
Status: UNKNOWN
Conditions: Metastatic Pancreatic Cancer
Interventions: DRUG: ABT-888 and mFOLFOX-6
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neural Operant Conditioning
Status: NOT_YET_RECRUITING
Conditions: Stroke|Chronic Stroke|Gait, Hemiplegic|Gait, Spastic|Walking, Difficulty
Interventions: DEVICE: Peripheral Nerve Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reverse Shoulder Arthroplasty With or Without Concomitant Latissimus and Teres Major Transfer for Shoulder Pseudoparalysis With Teres Minor Dysfunction
Status: COMPLETED
Conditions: Osteoarthritis of the Shoulder
Interventions: PROCEDURE: Transfer group|PROCEDURE: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Randomized Study to Compare Ultrasonic Drug Delivery to Standard of Care for the Treatment of Infections in Non-Healing Wounds
Status: UNKNOWN
Conditions: Acute Bacterial Skin and Skin Structure Infection (ABSSSI)|Non-healing Wound
Interventions: COMBINATION_PRODUCT: Ultrasonic Drug Delivery|DRUG: Standard of Care Antibiotic Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Systemic Therapy With or Without Local Consolidative Therapy in Treating Patients With Oligometastatic Solid Tumor
Status: ACTIVE_NOT_RECRUITING
Conditions: Oligometastatic Malignant Solid Neoplasm
Interventions: OTHER: Best Practice|PROCEDURE: Local Consolidation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: KV-CBCT and Ultrasound Imaging in Guiding Radiation Therapy in Patients With Prostate, Liver, or Pancreatic Cancer
Status: COMPLETED
Conditions: Adult Liver Carcinoma|Malignant Pancreatic Neoplasm|Prostate Carcinoma
Interventions: DEVICE: Cone-Beam Computed Tomography|RADIATION: 3-Dimensional Ultrasound-Guided Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Video-Based Exercise Program in Degenerative Meniscus Tears
Status: ENROLLING_BY_INVITATION
Conditions: Degenerative Disease|Meniscus Tear|Knee Pain Swelling
Interventions: OTHER: The video-based exercise (VBE) group|OTHER: The standard exercise group (SE)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Envarsus XR Compared to Immediate Release Tacrolimus
Status: ACTIVE_NOT_RECRUITING
Conditions: Kidney Transplant Recipients
Interventions: DRUG: Envarsus XR|DRUG: Tacrolimus twice daily
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of Lung Deposition of Aerosol Via HFNC in Healthy Adults
Status: UNKNOWN
Conditions: Healthy
Interventions: OTHER: 10l/min|OTHER: 30l/min|OTHER: 50l/min
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Brief Peer Supported webSTAIR Compared to Enhanced Wait List
Status: COMPLETED
Conditions: Post Traumatic Stress Disorder|Depression|Emotion Regulation
Interventions: OTHER: Brief Peer Supported webSTAIR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dexamethasone for the Treatment of Vasogenic Pericontusional Edema.
Status: UNKNOWN
Conditions: Traumatic Brain Injury|Cerebral Edema
Interventions: DRUG: Dexamethasone Oral|DRUG: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bridging the Gap From Postpartum to Primary Care
Status: ACTIVE_NOT_RECRUITING
Conditions: Hypertension|Hypertension in Pregnancy|Diabetes Mellitus|Gestational Diabetes|Obesity|Depressive Disorder|Anxiety Disorders
Interventions: BEHAVIORAL: Default appointment scheduling|BEHAVIORAL: Targeted messaging|BEHAVIORAL: Nudge Reminders
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Study to Evaluate the Anti-pruritic Effectiveness of ASN008 in Adults With Mild to Moderate Atopic Dermatitis
Status: COMPLETED
Conditions: Dermatitis, Atopic|Pruritus
Interventions: DRUG: ASN008|OTHER: ASN008 Matching Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Kappa Chimeric Antigen Receptor (CAR) T Lymphocytes Co-Expressing the Kappa and CD28 CARs for Relapsed/Refractory Kappa+ Non-Hodgkin Lymphoma and Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma.
Status: RECRUITING
Conditions: Mantle Cell Lymphoma|Follicular Lymphoma|Splenic Marginal Zone Lymphoma|Extranodal Marginal Zone Lymphoma of Mucosa-Associated Lymphoid Tissue|Nodal Marginal Zone Lymphoma|Indolent Non-hodgkin Lymphoma
Interventions: DRUG: CAR.k.28|DRUG: Fludarabine|DRUG: Cyclophosphamide|DRUG: Bendamustine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Breastfeeding Infants Receiving Respiratory Support Trial
Status: TERMINATED
Conditions: Intensive Care, Neonatal|Neonatal Respiratory Distress Syndrome|Continuous Positive Airway Pressure|Breast Feeding|Infant, Premature
Interventions: OTHER: Breast feeding|OTHER: Nasogastric feeding
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Hallucinations in Parkinson's Disease
Status: UNKNOWN
Conditions: Parkinson Disease Psychosis
Interventions: BEHAVIORAL: Clinical and neuropsychological assessments|BEHAVIORAL: Induction of PH and associated bodily states|OTHER: Resting-state fMRI acquisition|OTHER: Induction of PH and associated bodily states (MRI)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Nasal Expiratory Positive Airway Pressure for the Treatment of Pediatric Obstructive Sleep Apnea Syndrome
Status: COMPLETED
Conditions: Organic Pediatric Obstructive Sleep Apnea
Interventions: DEVICE: Nasal Expiratory Positive Airway Pressure Device|DEVICE: placebo sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Chimeric Vaccine to Prevent ETEC Diarrhea
Status: COMPLETED
Conditions: Escherichia Coli Infection
Interventions: BIOLOGICAL: Recombinant fimbrial adhesin dsc14CfaE-sCTA2/LTB5|BIOLOGICAL: Recombinant fimbrial adhesin dscCfaE|BIOLOGICAL: Modified E. coli heat labile enterotoxin LTR192G
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Phase 3 Study to Compare Safety and Efficacy of Smoflipid 20% to Intralipid 20% in Hospitalized Neonates and Infants
Status: TERMINATED
Conditions: Hospitalized Neonates and Infants, Expected to Require Parenteral Nutrition for 28 Days
Interventions: DRUG: Smoflipid 20% (investigational lipid for parenteral nutrition)|DRUG: Intralipid® 20%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study to Evaluate the Efficacy and Safety of Minocycline in Angelman Syndrome
Status: COMPLETED
Conditions: Angelman Syndrome
Interventions: DRUG: MINOCYCLINE|DRUG: PLACEBO (for Minocycline)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, and Efficacy of ISIS-PTP1BRx in Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus|Obese
Interventions: DRUG: ISIS-PTP1BRx|DRUG: Placebo|DRUG: daily OAD (metformin and/or sulfonylurea)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Interventional Therapy Sequential With the Fourth-generation CAR-T Targeting Nectin4/FAP for Malignant Solid Tumors
Status: UNKNOWN
Conditions: Nectin4-positive Advanced Malignant Solid Tumor
Interventions: BIOLOGICAL: CAR-T therapy for nectin4-positive malignant solid tumor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Wedge Resection and Segmentectomy for Ground Glass Opacity- Dominant Stage IA NSCLC
Status: RECRUITING
Conditions: Lung Neoplasms|Surgery
Interventions: PROCEDURE: Wedge resection|PROCEDURE: Segmentectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bosentan in Pulmonary Hypertension in Interstitial Lung Disease Treatment Study
Status: UNKNOWN
Conditions: Pulmonary Hypertension|Interstitial Lung Disease|Idiopathic Pulmonary Fibrosis|Nonspecific Interstitial Pneumonia
Interventions: DRUG: Bosentan|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Radial Pressure Waves Therapy in the Treatment of Non-Specific Neck Pain (rPWT)
Status: RECRUITING
Conditions: Neck Pain
Interventions: OTHER: Radial pressure waves Therapy|OTHER: Therapeutic Exercise and Manual Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Psychophysiological Effect of Simulated and Terrestrial Altitude
Status: COMPLETED
Conditions: Hypoxia|Altitude Hypoxia|Altitude Sickness|Altitude|Mountain Sickness|Hypoxia, Altitude
Interventions: BEHAVIORAL: Terrestrial altitude|BEHAVIORAL: Cloud 9
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Cryotechnique as a Diagnostic and Therapeutic Tool of Endobronchial Tumors
Status: COMPLETED
Conditions: Cryotherapy Effect|Bronchial Neoplasms
Interventions: PROCEDURE: Endobronchial cryobiopsy and cryotherapy using flexible bronchoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy of a Probiotic Lozenges in Chronic Periodontitis Patients.
Status: COMPLETED
Conditions: Chronic Periodontitis
Interventions: DRUG: Probiotic (Inersan)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Use of Transcranial Electrical Stimulation for Hallucinations
Status: TERMINATED
Conditions: Schizophrenia
Interventions: DEVICE: Transcranial Direct Current Stimulation|DEVICE: Transcranial Random Noise Stimulation|DEVICE: Transcranial Sham Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immune Modulation Study in Patients With Metastatic Melanoma Treated With Anti-PD1 Monoclonal Antibodies
Status: UNKNOWN
Conditions: Metastatic Melanoma
Interventions: BIOLOGICAL: blood sampling|DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effect of Ingesting a Tomato Pomace Extract on Platelet Aggregation
Status: COMPLETED
Conditions: Cardiovascular Diseases
Interventions: DIETARY_SUPPLEMENT: Placebo control|DIETARY_SUPPLEMENT: Low dose pomace extract|DIETARY_SUPPLEMENT: High dose pomace extract
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Randomized, Controlled Trial of Regular Sildenafil Citrate in the Prevention of Altitude Illness
Status: COMPLETED
Conditions: High Altitude Pulmonary Edema|Acute Mountain Sickness
Interventions: DRUG: Sildenafil citrate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pemetrexed and TAS-102 in Combination With Bevacizumab in Refractory Colorectal Cancer
Status: UNKNOWN
Conditions: Colorectal Neoplasms
Interventions: DRUG: Pemetrexed|DRUG: TAS-102|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Direct Pulp Capping Agent on Human Pulp Tissue
Status: RECRUITING
Conditions: Reversible Pulpitis
Interventions: DRUG: Biodentine|DRUG: Mineral Tri-Oxide Aggregate|DRUG: THERACAL LC|DRUG: TRISTRONTIUM ALUMINATE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: MNCH Programming in Southwest Uganda Maternal and Child Health In Bushenyi and Rubirizi Districts, UGANDA
Status: COMPLETED
Conditions: Child Mortality|Maternal Mortality (All Cause)
Interventions: OTHER: MNCH programming in health district
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Memantine for Disability in Amyotrophic Lateral Sclerosis (MEDALS)
Status: COMPLETED
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DRUG: Memantine (Ebixa)|DRUG: riluzole|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Randomized Clinical Trial of Change My Story
Status: NOT_YET_RECRUITING
Conditions: Hiv|Depression|Psychological Distress
Interventions: BEHAVIORAL: Problem Solving Therapy|OTHER: Change My Story
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Masitinib in Non-Resectable or Metastatic Stage 3/4 Melanoma Carrying a Mutation in the Juxta Membrane Domain of c-Kit
Status: TERMINATED
Conditions: Metastatic Melanoma
Interventions: DRUG: Masitinib|DRUG: Dacarbazine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of a Dietary Approach to Iron Deficiency in Premenopausal Women Affected by Celiac Disease
Status: UNKNOWN
Conditions: Celiac Disease|Iron Deficiency (Without Anemia)
Interventions: DRUG: Iron sulfate 105 mg|DIETARY_SUPPLEMENT: Iron-rich diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial of AMXI-5001 for Treatment in Patients With Advanced Malignancies
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Malignant Neoplasm|Breast Cancer|Ovarian Cancer|Homologous Recombination Deficiency|Prostate Cancer|Pancreatic Cancer
Interventions: DRUG: AMXI-5001:Dose Escalation Phase I|DRUG: AMXI-5001:Dose Expansion Phase II
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intrabdominal Hyperthermic Chemotherapy and Pancreatic Cancer
Status: RECRUITING
Conditions: Resectable Pancreatic Adenocarcinoma
Interventions: DRUG: HIPEC-gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Surgicel® Fibrillar for Delayed Bleeding After ESD
Status: COMPLETED
Conditions: Benign Neoplasm of Stomach|Malignant Neoplasm of Stomach
Interventions: OTHER: PPI|OTHER: H2RA and surgicel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: The Role of Clinical Pharmacist in Management of DDIs in CHF Patients
Status: UNKNOWN
Conditions: Chronic Heart Failure
Interventions: BEHAVIORAL: Advice on DDIs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: HEART Rate Variability Biofeedback in LOng COVID-19 (HEARTLOC)
Status: RECRUITING
Conditions: COVID-19
Interventions: BEHAVIORAL: Heart Rate Variability Biofeedback (HRV-B)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Home Follow-up After Medication Abortion
Status: WITHDRAWN
Conditions: Medical; Abortion, Fetus
Interventions: OTHER: Follow-up clinic visit|OTHER: Text message|OTHER: Low Sensitivity Pregnancy Test (LSPT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Efficacy of N-Acetylcysteine in Treatment of Overt Diabetic Nephropathy
Status: COMPLETED
Conditions: Diabetic Nephropathy|Chronic Kidney Disease|Diabetes Type 2
Interventions: DRUG: N-acetylcysteine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Danicopan as Add-on Therapy to a C5 Inhibitor in Paroxysmal Nocturnal Hemoglobinuria (PNH) Participants Who Have Clinically Evident Extravascular Hemolysis (EVH)(ALPHA)
Status: COMPLETED
Conditions: Paroxysmal Nocturnal Hemoglobinuria
Interventions: DRUG: Danicopan|DRUG: Placebo|DRUG: C5 Inhibitor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Double Lock Versus Continuous Non-locking Technique for Closure of Rectus Sheath in Cesarean Sections on Post-operative Pain
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: PROCEDURE: lower segment cesarean section and double lock closure of rectus sheath|PROCEDURE: lower segment cesarean section and continuous non-locking closure of rectus sheath
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Ranibizumab to Treat Choroidal Neovascularization (CNV) in Patients With Pseudoxanthoma Elasticum (PXE)
Status: COMPLETED
Conditions: Choroidal Neovascularization
Interventions: DRUG: Intravitreal injection ranibizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Bipolar vs Monopolar Transurethral Resection of Bladder Tumor-A Randomized Controlled Trial
Status: COMPLETED
Conditions: Obturator Jerk in TURBT
Interventions: DEVICE: TURBT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: mFOLFOX6 Chemotherapy With Apatinib as Postoperative Treatment in Stage IIIB or IIIC Colorectal Cancer
Status: COMPLETED
Conditions: Apatinib
Interventions: DRUG: Apatinib|DRUG: Oxaliplatin|DRUG: 5-fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Investigation of the LCS® Complete Posterior Stabilized Mobile-bearing Total Knee System
Status: COMPLETED
Conditions: Osteoarthritis|Rheumatoid Arthritis|Post-traumatic Arthritis|Juvenile Arthritis
Interventions: DEVICE: Total knee arthroplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Glucose Evaluation Through Continuous Glucose Monitors in Polycystic Ovary Syndrome
Status: RECRUITING
Conditions: PCOS (Polycystic Ovary Syndrome) of Bilateral Ovaries|Dysglycemia|Insulin Resistance
Interventions: DEVICE: DEXCOM Continuous Glucose Monitor (CGM)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Post-dilatation for Optimization of Drug-eluting Stents (DES) Deployment Assessed by Intravascular Ultrasound Multicenter Analysis
Status: UNKNOWN
Conditions: Implant
Interventions: PROCEDURE: post dilatation after stent deployment|PROCEDURE: stent deployment without post-dilatation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Facilitating Treatment Entry and Family Planning in Substance-using Neonatal Intensive Care Unit (NICU) Mothers
Status: COMPLETED
Conditions: Substance Use Disorders
Interventions: BEHAVIORAL: Motivational Interviewing (MI) and Acceptance and Commitment Therapy (ACT)|BEHAVIORAL: Conventional Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of AL-78898A in Exudative Age-Related Macular Degeneration
Status: COMPLETED
Conditions: Exudative Age-Related Macular Degeneration
Interventions: DRUG: AL-78898A|DRUG: Ranibizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating LAMICTAL Extended-Release Therapy Added To Current Seizure Treatments In Patients With Partial Seizures
Status: COMPLETED
Conditions: Epilepsy|Epilepsy, Partial
Interventions: DRUG: LAMICTAL extended-release
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Study of Treatment of Depression in Refractory Asthma
Status: UNKNOWN
Conditions: Asthma
Interventions: DRUG: Citalopram|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Labor Stages and Interventions on Hemodynamic Measures During & After Childbirth With Noninvasive Sensors
Status: COMPLETED
Conditions: Rupture of Membranes; Premature|Cesarean Section; Infection|Preeclampsia
Interventions: DEVICE: biobeat sensor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Utilization of Target Ranges to Treat Persons With Parkinson's Disease by Objective Measurement Using the PKG
Status: WITHDRAWN
Conditions: Parkinson Disease
Interventions: DEVICE: Personal KinetiGraph® (PKG®) System|DEVICE: Personal KinetiGraph® (PKG®) Watch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: INcentives and ReMINDers to Improve Long-term Medication Adherence
Status: ACTIVE_NOT_RECRUITING
Conditions: HIV/AIDS
Interventions: BEHAVIORAL: Daily Text Messages|BEHAVIORAL: Incentivization based on timely ART adherence
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Itacitinib for the Treatment of Chronic Graft Versus Host Disease (cGVHD)
Status: TERMINATED
Conditions: Chronic Graft-versus-host-disease
Interventions: DRUG: Itacitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sugammadex Hypersensitivity Study (Study P06042)
Status: COMPLETED
Conditions: Hypersensitivity
Interventions: DRUG: Placebo run-in dose|DRUG: Sugammadex 4 mg/kg|DRUG: Sugammadex 16 mg/kg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial of Rosiglitazone for Ulcerative Colitis
Status: COMPLETED
Conditions: Ulcerative Colitis|Inflammatory Bowel Disease
Interventions: DRUG: Rosiglitazone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of the Kv7-channel Opener Flupirtine on the Excitability of Human Peripheral Myelinated Axons in Vivo
Status: COMPLETED
Conditions: Axonal Change, Neuronal|Pain
Interventions: DRUG: flupirtine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Ozonated Gel Phonophoresis On Chronic Lateral Epicondylitis
Status: NOT_YET_RECRUITING
Conditions: Epicondylitis
Interventions: DEVICE: phonophoresis|OTHER: conventional physical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of a Springtime Home Cleanse on Skin, Gut, Metabolic and Mental Health
Status: UNKNOWN
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: 9-day detoxification cleanse and 1 week of pre-cleanse transition
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility and Impact of Malaria Rapid Diagnostic Tests in the African Retail Sector
Status: COMPLETED
Conditions: Malaria
Interventions: BEHAVIORAL: RDT Training and Subsidy Offered|BEHAVIORAL: Information/Education Campaign
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Does GM-CSF Restore Neutrophil Phagocytosis in Critical Illness?
Status: COMPLETED
Conditions: Critical Illness|Sepsis|Immuno-suppression
Interventions: DRUG: Leukine|DRUG: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Prospective Study to Determine the Safety and Effectiveness of a Connective Tissue Allograft Active Matrix (AM) vs. Standard of Care in Arthroscopic Rotator Cuff Repair
Status: NOT_YET_RECRUITING
Conditions: Rotator Cuff Tears
Interventions: OTHER: ActiveMatrix® Dosage A|OTHER: ActiveMatrix® Dosage B|PROCEDURE: Saline injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Combination of Everolimus and Octreotide LAR in Aggressive Recurrent Meningiomas
Status: COMPLETED
Conditions: Recurrent Meningiomas|Resistant Meningiomas
Interventions: DRUG: Everolimus|DRUG: Octreotide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of Intermittent Positive Pressure Breathing (IPPB)
Status: COMPLETED
Conditions: Lung Diseases|Lung Diseases, Obstructive|Chronic Obstructive Pulmonary Disease
Interventions: PROCEDURE: intermittent positive-pressure breathing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Reflex Excitability in Post-stroke Stiff-Knee Gait
Status: RECRUITING
Conditions: Stroke|Chronic Stroke|Gait, Hemiplegic|Gait, Spastic|Gait Disorder, Sensorimotor|Gait Disorders, Neurologic|Walking, Difficulty
Interventions: OTHER: Peripheral nerve stimulation|DEVICE: Commercial knee brace
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Phase 1 / 2 Dose Escalation Study of Locally-Administered OncoGel™ in Subjects With Recurrent Glioma
Status: TERMINATED
Conditions: Glioblastoma Multiforme|Brain Neoplasms
Interventions: DRUG: OncoGel (ReGel/Paclitaxel)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Precision Vaginal Microbiome Transplantation in Women With Bacterial Vaginosis
Status: RECRUITING
Conditions: Bacterial Vaginosis
Interventions: OTHER: Lactobacillus cispatus|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Standard Versus Hyperangulated Video Laryngoscopy Blades for Intubation in Neonates and Small Infants
Status: RECRUITING
Conditions: Intubation; Difficult or Failed
Interventions: DEVICE: Cobalt video laryngoscope blade|DEVICE: Miller video laryngoscope blade
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Investigate the Effect of Hepatic Impairment on the Pharmacokinetics, Safety, and Tolerability of AZD0780
Status: RECRUITING
Conditions: Hepatic Impairment
Interventions: DRUG: AZD0780
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of Umbilical Cord Mesenchymal Stem Cells (UC-MSC) for Treatment of Knee Osteoarthritis
Status: UNKNOWN
Conditions: Osteoarthritis of the Knee
Interventions: BIOLOGICAL: Umbilical-cord mesenchymal stromal cells (UC-MSCs)|OTHER: Hyaluronic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ABC-08: Phase Ib Trial of Acelarin in Combination With Cisplatin in Locally Advanced/ Metastatic Biliary Tract Cancers
Status: COMPLETED
Conditions: Biliary Tract Cancer|Gallbladder Cancer|Cholangiocarcinoma|Ampullary Cancer
Interventions: DRUG: Acelarin|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cardiovascular Contrast-enhanced Magnetic Resonance Imaging Using Polysaccharide Superparamagnetic Iron Oxide Injection in Diabetic Patients
Status: COMPLETED
Conditions: Diabetes|Magnetic Resonance Imaging
Interventions: DRUG: Polysaccharide superparamagnetic iron oxide injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Prospective Trial Comparing Transoral Endoscopic Thyroidectomy Vestibular Approach (TOETVA) and Conventional Open Thyroidectomy
Status: RECRUITING
Conditions: Benign Thyroid Nodule|Suspicious Malignant Thyroid Nodule
Interventions: PROCEDURE: Transoral endoscopic thyroidectomy vestibular approach (TOETVA)|PROCEDURE: Traditional Open Thyroidectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Hormonal Cahanges During Menstrual Cycle on Subcostal Transversus Abdominis Plane Block
Status: NOT_YET_RECRUITING
Conditions: Menstrual Cycle|Subcostal Transversus Abdominis Plane Block
Interventions: OTHER: Subcostal Transversus Abdominis Plane Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Standard Versus Transepithelial Corneal Crosslinking
Status: COMPLETED
Conditions: Keratoconus
Interventions: PROCEDURE: Transepithelial versus epithelium-off CXL|DRUG: Ricrolin TE|DRUG: Isotonic riboflavin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Social Media for ART Adherence and Retention in Adolescents and Young Adults: the Vijana-SMART Study
Status: COMPLETED
Conditions: HIV-1-infection|Adherence, Medication|Depression
Interventions: BEHAVIORAL: Vijana-SMART
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of Phenylephrine and Ephedrine in the Treatment of Hemodynamic Disorders After Spinal Anesthesia in the Elderly
Status: COMPLETED
Conditions: Hip Fractures|Elderly Patients|Spinal Anesthesia|Lower Limb Surgery
Interventions: DRUG: Ephedrine|DRUG: Phenylephrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Study of Pharmacokinetics, Safety and Tolerability of Intravenous Methylnaltrexone Bromide
Status: COMPLETED
Conditions: Healthy Adults
Interventions: DRUG: methylnaltrexone|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Aesthetic Performance of an Injective Treatment for the Inner Thighs, Knees and Arms
Status: COMPLETED
Conditions: Skin Flaccidity Inner Thighs Knees Arms
Interventions: DEVICE: SUNEKOS ® Body
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Safety and Efficacy of FG-3019 (Pamrevlumab) in Participants With Idiopathic Pulmonary Fibrosis (IPF)
Status: COMPLETED
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: DRUG: Pamrevlumab|DRUG: Placebo|DRUG: Sub-Study: Pirfenidone|DRUG: Sub-Study: Nintedanib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of Narlumosbart (JMT103) in Patients With Giant Cell Tumor of Bone
Status: NOT_YET_RECRUITING
Conditions: Giant Cell Tumor of Bone
Interventions: DRUG: Narlumosbart|DRUG: Denosumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: EMST and Swallowing in Long-Term Survivors of HNCA
Status: RECRUITING
Conditions: Head and Neck Neoplasms|Deglutition Disorders
Interventions: BEHAVIORAL: Expiratory Muscle Strength Training|BEHAVIORAL: Pharyngeal Muscle Strengthening Exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Physiotherapy in Patients Hospitalized Due to Pneumonia.
Status: UNKNOWN
Conditions: Pneumonia
Interventions: DRUG: cephalosporin with or without erythromycin|OTHER: Physiotherapy program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Unilateral Dual TAP (Transverses Abdominal Plane) Blok i Forbindelse Med Laparoskopisk Nyre Operation
Status: COMPLETED
Conditions: Laparoscopic Nephrectomy|TAP Block
Interventions: DRUG: TAP block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Safety of Elotuzumab Administered Over Approximately 60 Minutes in Combination With Lenalidomide and Dexamethasone for Newly Diagnosed or Relapsed/Refractory Multiple Myeloma Patients
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Elotuzumab|DRUG: Lenalidomide|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT