pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Clofarabine, Cytarabine, and Filgrastim Followed by Infusion of Non-HLA Matched Ex Vivo Expanded Cord Blood Progenitors in Treating Patients With Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Adult Acute Megakaryoblastic Leukemia (M7)|Adult Acute Minimally Differentiated Myeloid Leukemia (M0)|Adult Acute Monoblastic Leukemia (M5a)|Adult Acute Monocytic Leukemia (M5b)|Adult Acute Myeloblastic Leukemia With Maturation (M2)|Adult Acute Myeloblastic Leukemia Without Maturation (M1)|Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities|Adult Acute Myeloid Leukemia With Del(5q)|Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)|Adult Acute Myeloid Leukemia With t(15;17)(q22;q12)|Adult Acute Myeloid Leukemia With t(16;16)(p13;q22)|Adult Acute Myeloid Leukemia With t(8;21)(q22;q22)|Adult Acute Myelomonocytic Leukemia (M4)|Adult Acute Promyelocytic Leukemia (M3)|Adult Erythroleukemia (M6a)|Adult Pure Erythroid Leukemia (M6b)|Recurrent Adult Acute Myeloid Leukemia|Untreated Adult Acute Myeloid Leukemia
Interventions: DRUG: cytarabine|DRUG: clofarabine|DRUG: filgrastim|BIOLOGICAL: Ex-vivo expanded cord blood progenitor cell infusion|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pre-operative Short-term Administration of a Formula Diet Containing a Non-milk-derived Protein Source for Prevention of Acute Kidney Injury After Cardiac Surgery
Status: COMPLETED
Conditions: Acute Renal Failure|Acute Kidney Injury
Interventions: OTHER: Non-milked derived protein source formula diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Maximising Time With a Normal Blood Glucose to Restore the Glucagon Response in Type 1 Diabetes
Status: ACTIVE_NOT_RECRUITING
Conditions: Type 1 Diabetes|Type 1 Diabetes Mellitus With Hypoglycemia|Hypoglycemia|Hypoglycemia Unawareness|Glucagon Deficiency|Insulin Hypoglycemia
Interventions: PROCEDURE: Stepped hyperinsulinaemic-hypoglycaemic clamp study|DEVICE: Insulin pump|DEVICE: Continuous glucose monitor|OTHER: Low carbohydrate diet|DEVICE: Blinded continuous glucose monitor|PROCEDURE: Stable isotope studies- D2 Glucose and D5 Glycerol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Trial of Zinc and Micronutrients in Tanzanian Children
Status: COMPLETED
Conditions: Diarrheal Illnesses|Respiratory Illness|Growth Faltering
Interventions: DRUG: Zinc|DRUG: Multivitamins|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Spinal Anaesthesia for Knee Arthroscopy: Does Lignocaine Shorten the Effect of Bupivacaine
Status: COMPLETED
Conditions: Spinal Anesthesia
Interventions: DRUG: Lidocaine|DRUG: bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PF-3512676 (CPG 7909) Injection For Patients Who Completed An Oncology Study Using PF-3512676 (CPG 7909)
Status: COMPLETED
Conditions: Melanoma|Breast Neoplasms|Carcinoma, Renal Cell|Lymphoma, T-Cell|Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: PF-3512676
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 1, Single and Multiple Doses Study of Sitaxentan in Japanese and Western Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Sitaxentan sodium/Placebo|DRUG: Sitaxentan sodium/Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dose-escalation Trial of Preoperative Radiotherapy and Concurrent Chemotherapy in Locally Advanced Rectal Cancer
Status: UNKNOWN
Conditions: Locally Advanced Rectal Cancer
Interventions: RADIATION: 3DCRT treatment (sequential boost)|RADIATION: Dose Escalation Intensity Modulated Radiotherapy treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Soft Tissue Wound Healing Following Different Gingivectomy Techniques
Status: COMPLETED
Conditions: Gingival Overgrowth
Interventions: DEVICE: Ceramic rotary bur|DEVICE: Diode laser|DEVICE: Scalpel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Oral Nutritional Supplements on Body Weight Loss of Patients With Nasopharyngeal Carcinoma
Status: RECRUITING
Conditions: Nasopharyngeal Carcinoma|Nutritional Support
Interventions: DIETARY_SUPPLEMENT: Abbott®Ensure|RADIATION: Intensity Modulated Radiation Therapy|DRUG: cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Is a Knee Arthroscopy of Any Benefit for the Middleaged Patient With Meniscal Symptoms?
Status: COMPLETED
Conditions: Chronic Meniscus Injury
Interventions: PROCEDURE: Knee arthroscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Performance of Elucirem® in DSC-MRI Perfusion of Brain Gliomas
Status: RECRUITING
Conditions: Brain Tumor, Primary|Brain Tumor, Recurrent
Interventions: DRUG: Elucirem|DRUG: Dotarem
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety of Effivia®, a Bevacizumab Biosimilar
Status: RECRUITING
Conditions: Metastatic Colorectal Cancer|Metastatic Cervical Cancer|Non Squamous Non Small Cell Lung Cancer
Interventions: DRUG: Bevacizumab Biosimilar MB02
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of MM-151 + Nal-IRI + 5-FU + Leucovorin in RAS/RAF Wild-type Metastatic Colorectal Cancer
Status: WITHDRAWN
Conditions: Colorectal Cancer
Interventions: DRUG: MM-151|DRUG: nal-IRI|DRUG: Leucovorin|DRUG: 5-FU
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of the Non-invasive Brain Stimulation on the Speech Fluency Enhancement
Status: COMPLETED
Conditions: Stuttering/ Developmental
Interventions: DEVICE: Anodal tDCS|BEHAVIORAL: fluency intervention/ Delayed Auditory Feedback|DEVICE: Sham tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Optic Nerve Sheath Diameter: A Non-Invasive Indicator of Intracranial Pressure in the Intensive Care Unit Monitoring
Status: COMPLETED
Conditions: ICP (Intracranial Pressure) Increase|Optic Nerve Sheath Diameter|Intracranial Hypertension
Interventions: PROCEDURE: After 5 ml CSF Drainage
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Phase III Clinical Study of Pegylated Somatropin (PEG Somatropin) to Treat Growth Hormone Deficiency Children
Status: COMPLETED
Conditions: Growth Hormone Deficiency
Interventions: BIOLOGICAL: PEG-somatropin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Acute Tryptophan Depletion (ATD) on Esophageal Sensitivity in Healthy Volunteers
Status: COMPLETED
Conditions: Esophageal Sensitivity
Interventions: DIETARY_SUPPLEMENT: Acute tryptophan depletion|DIETARY_SUPPLEMENT: Placebo|DEVICE: Multimodal stimulation probe
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Neutrophil Extracellular Traps in Different Forms of Systemic Sclerosis
Status: RECRUITING
Conditions: Systemic Sclerosis|Other Connective Tissue Disease|Systemic Lupus Erythematosus|Dermatomyositis|ANCA Associated Vasculitis
Interventions: OTHER: Blood sample
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Is Kinesio Taping More Effective Than Medical Adhesive Tape in Patients With Chronic Non-specific Low Back Pain?
Status: COMPLETED
Conditions: Low Back Pain
Interventions: OTHER: Kinesio Taping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Core Strengthening vs Pilates Exercises on Posture, Body Awareness and Fatigue Among Female Athletes
Status: COMPLETED
Conditions: Exercise Movement Techniques|Muscle Strength|Athletes|Posture
Interventions: OTHER: core strengthening exercise|OTHER: Pilates exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Comparison of Bronchodilator Treatment Practices in Group E COPD Patients
Status: NOT_YET_RECRUITING
Conditions: COPD Exacerbation Acute
Interventions: DEVICE: Comparison of bronchodilator effectiveness of nebulizer therapy devices
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Carrelizumab Combined With Chemotherapy for Adjuvant Therapy of Esophageal Squamous Cell Carcinoma
Status: RECRUITING
Conditions: Esophagus Cancer
Interventions: DRUG: Camrelizumab|DRUG: Paclitaxel|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Laser Therapy Effect on Oral Mucositis in Childhood Acute Lymphoblastic Leukemia Patients
Status: RECRUITING
Conditions: Oral Mucositis|Childhood Acute Lymphoblastic Leukemia
Interventions: DEVICE: Laser Therapy|DEVICE: Sham procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Relative Bioavailability of Two Lutikizumab Formulations and Pharmacokinetics, Safety, and Tolerability of Lutikizumab in Chinese Participants
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Lutikizumab Dose A|DRUG: Lutikizumab Dose B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Preoperative Magnetic Resonance Imaging to Obtain Adequate Resection Margins in Breast Conserving Surgery, (PRIMAR) Trial
Status: RECRUITING
Conditions: Breast Cancer
Interventions: DEVICE: Breast MRI|DIAGNOSTIC_TEST: standard breast imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Investigation of the Relationship Between Central Sensitization and Neuropathic Pain in Lumbar Disc Herniation
Status: RECRUITING
Conditions: Central Sensitisation
Interventions: DIAGNOSTIC_TEST: Central sensitization inventory|OTHER: Short form-36|OTHER: Oswestry Low Back Pain Disability Questionnaire|OTHER: Douleur Neuropathique 4|OTHER: Visual analogue scale
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: SIMPLifying Elements of Standardized Automated Office Blood Pressure Measurements (Pilot Study)
Status: NOT_YET_RECRUITING
Conditions: Blood Pressure
Interventions: DIAGNOSTIC_TEST: Mean awake ambulatory BP measurements
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Rectal Acetaminophen During Oocyte Retrievals
Status: NOT_YET_RECRUITING
Conditions: Oocyte Retrieival and Post Operative Pain Control
Interventions: DRUG: Tylenol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Drug-Drug Interaction Study Between Danoprevir/Low-Dose Ritonavir and Cyclosporine in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: cyclosporine|DRUG: danoprevir|DRUG: ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: An Open-Label Study of Aficamten for Chinese Patients With Symptomatic oHCM
Status: RECRUITING
Conditions: Obstructive Hypertrophic Cardiomyopathy
Interventions: DRUG: Aficamten
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of XL147 (SAR245408) or XL765 (SAR245409) in Combination With Letrozole in Subjects With Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: XL147 (SAR245408)|DRUG: XL765 (SAR245409)|DRUG: letrozole (Femara)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of IDEC-114 in the Treatment of Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Non-Hodgkin's Lymphoma
Interventions: DRUG: IDEC-114
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Iron Deposits in the Pancreas by MRI Method of Dialysis Patients With Hemosiderosis Iatrogenic (ERDFP)
Status: NOT_YET_RECRUITING
Conditions: Iron Deposition|Dialysis|Iatrogenic Hemosiderosis
Interventions: PROCEDURE: MRI
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Renal Denervation in Patients With Chronic Heart Failure
Status: WITHDRAWN
Conditions: Chronic Heart Failure|Cardio-Renal Syndrome
Interventions: DEVICE: Renal denervation (Symplicity™)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Feasibility Study of Integrating Maternal Nutrition Interventions Into Antenatal Care Services in Ethiopia
Status: COMPLETED
Conditions: Maternal Dietary Diversity|Iron-Folic Acid Supplementation|Early Initiation of Breastfeeding
Interventions: BEHAVIORAL: Health Facility Interventions|BEHAVIORAL: Community Interventions|BEHAVIORAL: Health System Interventions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effects of Denosumab on Bone Microarchitecture After Total Knee Arthroplasty
Status: UNKNOWN
Conditions: Osteoarthritis, Knee
Interventions: DRUG: Denosumab 60 MG/ML Injectable Solution [Prolia]|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Repeat Nasal Allergen Challenge
Status: COMPLETED
Conditions: Hayfever
Interventions: PROCEDURE: Skin Prick Test|PROCEDURE: Nasal allergen challenge|PROCEDURE: Nasal filter paper placement|PROCEDURE: Nasal lavage|PROCEDURE: Nasal scrape|PROCEDURE: Nasal symptoms score
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Fludeoxyglucose F 18 Positron Emission Tomography in Predicting Risk of Relapse in Patients With Non-Hodgkin's Lymphoma Who Are Undergoing Combination Chemotherapy With or Without Autologous Stem Cell or Bone Marrow Transplant
Status: COMPLETED
Conditions: Lymphoma
Interventions: BIOLOGICAL: filgrastim|BIOLOGICAL: rituximab|DRUG: busulfan|DRUG: cisplatin|DRUG: cyclophosphamide|DRUG: cytarabine|DRUG: doxorubicin hydrochloride|DRUG: etoposide|DRUG: methylprednisolone|DRUG: prednisone|DRUG: vincristine sulfate|PROCEDURE: autologous bone marrow transplantation|PROCEDURE: peripheral blood stem cell transplantation|PROCEDURE: positron emission tomography|RADIATION: fludeoxyglucose F 18|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluating the Safety and Effectiveness of a Dengue Virus Vaccine in Healthy Adults
Status: COMPLETED
Conditions: Dengue
Interventions: BIOLOGICAL: TetraVax-DV-TV003|BIOLOGICAL: rDEN2∆30-7169|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Intervention Study on Iodine Biofortification Vegetables ( Nutri-I-Food
Status: COMPLETED
Conditions: Healthy Individuals
Interventions: DIETARY_SUPPLEMENT: Lettuce with not biofortification|DIETARY_SUPPLEMENT: Lettuce biofortificated with Iodine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effect of a Liquid Protein Modular on Growth and Outcomes in the NICU
Status: COMPLETED
Conditions: Problem With Growth of an Infant
Interventions: DIETARY_SUPPLEMENT: Powder protein modular|DIETARY_SUPPLEMENT: Liquid protein modular
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluate the Efficacy and Safety of "Formosa 1-Breath Free (NRICM101) " in Subjects With the Symptoms of COVID-19 or Influenza-like Disease
Status: NOT_YET_RECRUITING
Conditions: Influenza Viral Infections|COVID-19
Interventions: DRUG: Formosa 1-Breath Free (NRICM101)|DRUG: Placebo control drug
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Bifido Bacteria to Improve Lactose Digestion and Tolerance
Status: RECRUITING
Conditions: Lactose Intolerance
Interventions: DIETARY_SUPPLEMENT: Bifidobacterium adolescentis IVS-1 capsule|OTHER: Placebo cellulose capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Customizing Myopia Control With Multifocal Toric Contact Lens
Status: WITHDRAWN
Conditions: Refractive Errors|Myopia
Interventions: DEVICE: Intelliwave multifocal, toric, soft contact lens|DEVICE: Intelliwave toric, soft contact lens
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neurectomy Vs Nerve Sparing in Open Inguinal Hernia Repair
Status: COMPLETED
Conditions: Inguinal Hernia
Interventions: PROCEDURE: Neurectomy in inguinal hernia repair|PROCEDURE: nerve sparing in inguinal hernia repair
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Drain Antisepsis After Tissue Expander Breast Reconstruction
Status: COMPLETED
Conditions: Nonmalignant Breast Conditions|Breast Cancer
Interventions: DEVICE: Sodium hypochlorite (Dakin's Solution)|DEVICE: Chlorhexidine gluconate disk|PROCEDURE: Control|DEVICE: Occlusive Adhesive Dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Second Clinical Evaluation of THERANOVA-500 Dialyzer in Chronic Hemodialysis (HD)
Status: UNKNOWN
Conditions: End Stage Renal Disease on Dialysis
Interventions: DEVICE: THERANOVA-500 dialyzer|DEVICE: REVACLEAR-400 dialyzer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: A Multi-site Feasibility Clinical Trial of Retraining and Control Therapy (ReACT), a Mind and Body Treatment for Pediatric Functional Seizures
Status: RECRUITING
Conditions: Functional Seizures|Convulsion, Non-Epileptic
Interventions: BEHAVIORAL: ReACT|BEHAVIORAL: CATCH-IT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of STX209 (Arbaclofen) for Social Withdrawal in Adolescents and Adults With Fragile X Syndrome
Status: COMPLETED
Conditions: Fragile X Syndrome
Interventions: DRUG: arbaclofen|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Therapy With Ursodeoxycholic Acid (UDCA) and All-Trans Retinoic Acid (ATRA) for Treatment of Primary Sclerosing Cholangitis
Status: COMPLETED
Conditions: Cholangitis, Sclerosing
Interventions: DRUG: Oral all-trans retinoic acid (ATRA)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Role of Hyoid Suspension With Barbed Reposition Pharyngoplasty in Management of Lateral Pharyngeal Wall Collapse in Obstructive Sleep Apnea Patients
Status: UNKNOWN
Conditions: Obstructive Sleep Apnea
Interventions: PROCEDURE: Hyoid suspension
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Correlation Between Molecular Typing and Neoadjuvant Chemotherapy in Breast Cancer Patients Based on Mammaprint/Blueprint Test
Status: UNKNOWN
Conditions: Evaluation of the Value of Mammaprint Test Gene Variation in the Prediction of Neoadjuvant Chemotherapy for Breast Cancer
Interventions: COMBINATION_PRODUCT: neoadjuvant chemotherapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Romidepsin Versus Combination of Romidepsin Plus Pralatrexate in PTCL
Status: WITHDRAWN
Conditions: Lymphoma, T-Cell, Peripheral
Interventions: DRUG: Romidepsin|DRUG: Pralatrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effects of Normobaric Hypoxia Exercise Program on Bone Turnover Markers and Metabolism in Premenopausal Women
Status: RECRUITING
Conditions: Hypoxia
Interventions: OTHER: exercise and environmental conditions|OTHER: exercise and environmental conditions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Hemodynamic Response to Exercise in HFpEF Patients After Upregulation of SERCA2a
Status: COMPLETED
Conditions: Heart Failure, Congestive
Interventions: DRUG: Istaroxime|OTHER: Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Bintrafusp Alfa and Pimasertib for the Treatment of Patients With Brain Metastases
Status: COMPLETED
Conditions: Anatomic Stage IV Breast Cancer AJCC v8|Clinical Stage IV Cutaneous Melanoma AJCC v8|Hematopoietic and Lymphoid Cell Neoplasm|Hormone Receptor Positive Breast Adenocarcinoma|Metastatic Lung Non-Small Cell Carcinoma|Metastatic Malignant Neoplasm in the Brain|Metastatic Malignant Solid Neoplasm|Metastatic Melanoma|Metastatic Triple-Negative Breast Carcinoma|Pathologic Stage IV Cutaneous Melanoma AJCC v8|Prognostic Stage IV Breast Cancer AJCC v8|Stage IV Lung Cancer AJCC v8|Stage IVA Lung Cancer AJCC v8|Stage IVB Lung Cancer AJCC v8
Interventions: DRUG: Bintrafusp Alfa|DRUG: Pimasertib|OTHER: Quality-of-Life Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of RAD001 in Treating Plexiform Neurofibromas (PN) Associated With Neurofibromatosis (NF1)
Status: TERMINATED
Conditions: Plexiform Neurofibroma Associated With Neurofibromatosis Type 1
Interventions: DRUG: Everolimus (RAD001)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Probiotic Supplement and Microbiome, Immune System and Metabolic Syndrome
Status: COMPLETED
Conditions: Metabolic Syndrome|Microbiome|Immune Function|Inflammation
Interventions: DIETARY_SUPPLEMENT: Probiotic supplement|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Immunogenicity of PanBlok Influenza Vaccine in Healthy Adults
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: 0.5mL Intramuscular Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Treatment of Poor Ovarian Responders With Corifollitropin Alfa Followed by hpHMG in a Short GnRH Agonist Protocol
Status: COMPLETED
Conditions: Infertility|Poor Ovarian Response
Interventions: DRUG: Triptorelin|DRUG: Corifollitropin alfa|DRUG: hpHMG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Octreotide in Preventing or Reducing Diarrhea in Patients Receiving Chemoradiotherapy for Anal or Rectal Cancer
Status: COMPLETED
Conditions: Anal Cancer|Colorectal Cancer|Drug/Agent Toxicity by Tissue/Organ|Radiation Enteritis
Interventions: DRUG: octreotide acetate|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Pilot Study to Evaluate Safety and Performance of Neuromuscular Electrical Stimulation With the Inko RS Device for the Treatment of Stress Urinary Incontinence
Status: COMPLETED
Conditions: Stress Urinary Incontinence
Interventions: DEVICE: Inko RS Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Ixmyelocel-T (Formerly Catheter-based Cardiac Repair Cell [CRC]) Treatment in Patients With Heart Failure Due to Dilated Cardiomyopathy
Status: COMPLETED
Conditions: Dilated Cardiomyopathy
Interventions: BIOLOGICAL: Ixmyelocel-T|OTHER: Vehicle Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 2, Study of Ficlatuzumab Plus Erlotinib vs. Placebo Plus Erlotinib in Subjects With Previously Untreated Metastatic, EGFR-mutated NSCLC and BDX004 Positive Label
Status: TERMINATED
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: Ficlatuzumab|DRUG: Erlotinib|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intranasal Sufentanil Pain-management at Entrance of Emergency Department : Influence on Pain-relief Delay
Status: COMPLETED
Conditions: Single Traumatic Limb Injury With Severe Pain (Score > 5/10 on Numerical Pain Scale)
Interventions: DRUG: Placebo|DRUG: Sufentanil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Depemokimab in Participants With Hypereosinophilic Syndrome, Efficacy, and Safety Trial
Status: RECRUITING
Conditions: Hypereosinophilic Syndrome
Interventions: DRUG: Depemokimab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mechanism of Action Underlying Ketamine's Antidepressant Effects: The AMPA Throughput Theory in Patients With Treatment-Resistant Major Depression
Status: RECRUITING
Conditions: Depression|Major Depressive Disorder|Major Depression
Interventions: DEVICE: Arm 1, 2, 3 device interventions|OTHER: Arm 2 Interventions|DRUG: Arm 1, 2, 3 drug Interventions|DRUG: Arm 1 and 2 Interventions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Inhaled Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) in Hereditary Pulmonary Alveolar Proteinosis (PAP)
Status: COMPLETED
Conditions: Hereditary Pulmonary Alveolar Proteinosis
Interventions: DRUG: Leukine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Research Study to Assess the Mechanism By Which Glucovance, Metformin, and Glyburide Work To Control Glucose Levels In Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Non-Insulin-Dependent
Interventions: DRUG: Glucovance (metformin HCl/glyburide)|DRUG: or Metformin HCl alone|DRUG: or Glyburide alone.
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Isolated Limb Perfusion of Melphalan With or Without Tumor Necrosis Factor in Treating Patients With Soft Tissue Sarcoma of the Arm or Leg
Status: COMPLETED
Conditions: Stage IVB Adult Soft Tissue Sarcoma|Stage IIB Adult Soft Tissue Sarcoma|Stage IIC Adult Soft Tissue Sarcoma|Recurrent Adult Soft Tissue Sarcoma|Stage IVA Adult Soft Tissue Sarcoma|Stage III Adult Soft Tissue Sarcoma
Interventions: DRUG: melphalan|DRUG: tumor necrosis factor
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Haemodynamic Stability of Ketamine/Propofol Admixture "Ketofol" in Patient Undergoing Endoscopic Retrograde Cholangio Pancreatography
Status: TERMINATED
Conditions: Pancreatitis|Cholangitis
Interventions: DRUG: Ketamine / Propofol Admixture|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: To Test the Effect of Calcifediol Hy.D Supplementation on Muscle Function and Bone Quality in Younger Postmenopausal Women With Osteopenia
Status: COMPLETED
Conditions: Osteopenia/Osteoporosis
Interventions: DIETARY_SUPPLEMENT: Calcifediol|DIETARY_SUPPLEMENT: Vitamin D3|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Amicar for Children Having Craniofacial Surgery
Status: ACTIVE_NOT_RECRUITING
Conditions: Craniosynostosis
Interventions: DRUG: Amicar (ε-aminocaproic acid)|DRUG: normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Rituximab in Progressive Immunoglobulin A (IgA) Nephropathy
Status: COMPLETED
Conditions: IgA Nephropathy
Interventions: DRUG: Intravenous Rituximab|DRUG: ACE/ARB|DIETARY_SUPPLEMENT: Omega-3 Fatty Acid Fish Oil Supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Screening COVID-19 by Point-of-care Lung Ultrasound: a Validation Study
Status: UNKNOWN
Conditions: COVID-19 Pneumonia|Lung Ultrasound
Interventions: DIAGNOSTIC_TEST: Lung ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Ixazomib Plus Pomalidomide and Dexamethasone in Treating Patients With Relapsed or Relapsed/Refractory Multiple Myeloma
Status: COMPLETED
Conditions: Refractory Plasma Cell Myeloma|Recurrent Plasma Cell Myeloma
Interventions: DRUG: ixazomib citrate|DRUG: dexamethasone|DRUG: pomalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Stoss Therapy of Vitamin D3 on Peri-operative Outcomes in Patients Receiving General Surgery
Status: WITHDRAWN
Conditions: Vitamin D Deficiency|Surgery
Interventions: DRUG: Vitamin D3|OTHER: 95% MCT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: NBTXR3 Crystalline Nanoparticles and Radiation Therapy in Treating Patients With Soft Tissue Sarcoma of the Extremity
Status: COMPLETED
Conditions: Adult Soft Tissue Sarcoma
Interventions: DEVICE: NBTXR3
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Hydroxychloroquine Sulphate in Healthy Lean Females
Status: UNKNOWN
Conditions: Obesity
Interventions: DRUG: Hydroxychloroquine Sulphate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Dopamine and Muscle Function in the Heat
Status: UNKNOWN
Conditions: Muscle Force|Hyperthermia
Interventions: DRUG: Ritalin 20 mg Tablet|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Telemedicine Use in Preoperative Counseling for Endometrial Cancer Survivors
Status: RECRUITING
Conditions: Telemedicine|Counseling
Interventions: BEHAVIORAL: Preoperative counseling|BEHAVIORAL: Asynchronous telemedicine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Black Seed Oil in Treatment of Osteoarthritis
Status: COMPLETED
Conditions: Osteo Arthritis Knee
Interventions: DIETARY_SUPPLEMENT: Black seed oil capsule|DIETARY_SUPPLEMENT: Placebo Black seed oil capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Stereotactic Body Radiotherapy and Microwave Ablation for Recurrent Small Hepatocellular Carcinoma
Status: UNKNOWN
Conditions: Recurrent Hepatocellular Carcinoma|Microwave Ablation|Stereotactic Body Radiotherapy
Interventions: DEVICE: microwave ablation (MWA)|RADIATION: stereotactic body radiotherapy (SBRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Coping Skills for Patients With Chronic Obstructive Pulmonary Disease (COPD) and Their Caregivers
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: BEHAVIORAL: Telephone-based Enhanced Coping Skills Training (CST)|OTHER: Usual Medical Care and COPD education and symptom monitoring (UMC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Tai Chi Chuan on Psychobiological Indicators of Anxiety and Sleep Quality in Young Adults
Status: COMPLETED
Conditions: Anxiety
Interventions: BEHAVIORAL: Anxiety Management Education|BEHAVIORAL: 10 week tai chi intervention|BEHAVIORAL: Enhanced tai chi instruction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of AT-1501 in Patients With IgA Nephropathy (IgAN)
Status: TERMINATED
Conditions: IgA Nephropathy|IgAN
Interventions: DRUG: AT-1501
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Rehabilitation After Transfemoral Amputation in Moderately Active Patients
Status: RECRUITING
Conditions: Transfemoral Amputation
Interventions: OTHER: Amputation-specialized rehabilitation|OTHER: Non-amputation-specialized rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: 3DPCT Combined With CT Guided RISI in the Treatment of Thoracic Malignant Tumors
Status: RECRUITING
Conditions: Radioactive Iodine-125 Brachytherapy|Thoracic Cancer|3D Printing Coplanar Template|Nuclear Radiation Effects
Interventions: RADIATION: Radioactive seed brachytherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Filling Bone Defects/Voids With Autologous BonoFill For Maxillofacial Bone Regeneration
Status: COMPLETED
Conditions: Bone Void in the Maxillofacial Area
Interventions: PROCEDURE: Single Arm - Liposuction procedure and BonoFill transplantation will be done for all subjects on study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Dietary Palmitic Acid Triacylglyceride Position on Bone Strength Parameters in Infants
Status: COMPLETED
Conditions: Personal Satisfaction
Interventions: OTHER: InFat™ based infant formula|OTHER: Standard vegetable oil based infant formula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Epicardial Infarct Repair Using CorMatrix®-ECM: Clinical Feasibility Study
Status: COMPLETED
Conditions: Acute Coronary Syndrome|Heart Failure
Interventions: DEVICE: Epicardial Infarct Repair with CorMatrix-ECM|PROCEDURE: Coronary Artery Bypass Grafting Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Risk Factors of Post-ERCP Sepsis
Status: RECRUITING
Conditions: Sepsis|Intraoperative Hypotension|Bacteremia Sepsis
Interventions: PROCEDURE: exposure to hypotension during the Endoscopic Retrograde Cholangiopancreatography (ERCP) for obstructive jundice.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Predictors of Treatment Response to Aflibercept and Aqueous Cytokine Levels in Patients With Persistent Diabetic Macular Edema Following Treatment With Ranibizumab: An Interventional Prospective Study
Status: UNKNOWN
Conditions: Diabetic Macular Edema
Interventions: BIOLOGICAL: aflibercept
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I/II Study of CK-101 in NSCLC Patients and Other Advanced Solid Tumors
Status: COMPLETED
Conditions: Lung Neoplasms|Carcinoma, Non-Small-Cell Lung|Lung Diseases|Adenocarcinoma
Interventions: DRUG: CK-101
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transepithelial Corneal Collagen Crosslinking for Keratoconus and Corneal Ectasia
Status: ACTIVE_NOT_RECRUITING
Conditions: Keratoconus|Corneal Ectasia
Interventions: DRUG: Riboflavin|DRUG: Riboflavin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Sequential or Concomitant Therapy for Helicobacter Pylori Infection
Status: COMPLETED
Conditions: Helicobacter Infection
Interventions: DRUG: 10-day sequential treatment|DRUG: 10-day concomitant therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: PPOS vs GnRH Antagonist in Ovarian Stimulation (ProGanOS Study)
Status: RECRUITING
Conditions: Progestins Primed Ovarian Stimulation
Interventions: DRUG: Dydrogesterone 10 mg|DRUG: Cetrorelix 0.25 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Radiation Therapy and Paclitaxel and Carboplatin in Patients With Uterine Papillary Serous Carcinoma
Status: COMPLETED
Conditions: Uterine Cancer
Interventions: DRUG: Carboplatin and Paclitaxel and Pelvic Radiation Therapy|PROCEDURE: Carboplatin and Paclitaxel and Pelvic Radiation Therapy|DRUG: Carboplatin and Paclitaxel and Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PDCN for Treatment of Cervical Vertigo
Status: UNKNOWN
Conditions: Cervical Vertigo
Interventions: PROCEDURE: percutaneous disc decompression with coblation nucleoplasty|PROCEDURE: Manual Therapy (SNAGs plus PJMs)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of LY3041658 in Participants With Skin Diseases
Status: COMPLETED
Conditions: Skin Diseases|Psoriasis
Interventions: DRUG: LY3041658|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Treatment With the Ketone Body 3-hydroxybutyrate in Patients With Cardiogenic Shock
Status: COMPLETED
Conditions: Cardiogenic Shock
Interventions: DIETARY_SUPPLEMENT: KetoneAid Ketone Ester|DIETARY_SUPPLEMENT: Maltodextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Impact of Aspirin Dose Modification on the Innate Immune Response - Will Lower Dose Aspirin Therapy Reduce the Response to Endotoxin
Status: COMPLETED
Conditions: Acute Coronary Syndrome
Interventions: DRUG: Aspirin|DRUG: Ticagrelor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Single-Radiolabeled Dose Mass Balance Study To Investigate The Absorption, Metabolism, And Excretion Of [14C] Palbociclib (PD-0332991) In Healthy Male Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: RADIATION: [14C]-PD-0332991
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of New Tablet Formulations and Suspension Formulation Compared to Current (1B) Formulation of BILR 355 BS in Healthy Male Volunteer Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BILR 355 BS /1B, current low dose formulation|DRUG: BILR 355 BS /1B, current high dose formulation|DRUG: BILR 355 BS - Jet Milled (JM) + Sodium Dodecyl Sulfate (SDS) formulation|DRUG: BILR 355 BS - Hammer Milled (HM) + Sodium Dodecyl Sulfate (SDS) formulation|DRUG: BILR 355 BS - Suspension low dose|DRUG: BILR 355 BS - Suspension high dose|DRUG: Ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Using an APP in Post Oral Cancer Surgery to Affect Patients' Needs and Quality of Life.
Status: COMPLETED
Conditions: Oral Cancer
Interventions: DEVICE: Mobile health application (APP)|OTHER: Routine health care and instruction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: SEMA4D Blockade Safety and Brain Metabolic Activity in Alzheimer's Disease (AD)
Status: COMPLETED
Conditions: Alzheimer Disease
Interventions: DRUG: Pepinemab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Xenon-129 Lung Magnetic Resonance Imaging: Study of Healthy Volunteers and Participants With Pulmonary Disease
Status: RECRUITING
Conditions: Cystic Fibrosis|Asthma
Interventions: DRUG: Xenon-129|DEVICE: Magnetic Resonance Imaging|DEVICE: Lung Clearance Index
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparison of Capsular Stretching and Passive Joint Mobilization in Idiopathic Adhesive Capsulitis
Status: COMPLETED
Conditions: Adhesive Capsulitis
Interventions: OTHER: Mobilization|OTHER: Cyriax capsular stretching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant CCI-779 Followed By Radical Prostatectomy in Treating Patients With Newly Diagnosed Prostate Cancer Who Have a High Risk of Relapse
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: temsirolimus|PROCEDURE: conventional surgery|PROCEDURE: neoadjuvant therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dynamic SAX vs Conventional LAX in Internal Jugular Vein Catheterization
Status: COMPLETED
Conditions: Cardiac Surgical Procedures|Central Venous Catheterization|Ultrasonography
Interventions: PROCEDURE: Dynamic needle tip positioning under ultrasound-guidance|PROCEDURE: Conventional long-axis view
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Randomized Ph 2 Trial Of Paclitaxel/Carboplatin /Bevacizumab + PF-3512676 And P/C/B Alone In Advanced Nonsquamous NSCLC
Status: TERMINATED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: paclitaxel + carboplatin + bevacizumab|DRUG: carboplatin + paclitaxel + bevacizumab + PF-3512676
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Echinacea Purpurea and Osteopathy in Children With Recurrent Otitis Media
Status: COMPLETED
Conditions: Otitis Media
Interventions: PROCEDURE: Cranial osteopathic manipulative treatment.|DIETARY_SUPPLEMENT: Echinacea purpurea|PROCEDURE: Sham osteopathic manipulative treatment|DIETARY_SUPPLEMENT: "Echinacea purpurea" placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION