pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: An Emotional Regulation Brief Procedure (PbRE) for Fibromyalgia Using ICT's
Status: UNKNOWN
Conditions: Fibromyalgia|Chronic Pain
Interventions: BEHAVIORAL: PBrE|BEHAVIORAL: PBrE-Control|BEHAVIORAL: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Explored About Temperature Packing Care to Improve the Quality of Life for Chemotherapy Induced Peripheral Neuropathy (CIPN) in Colorectal Cancer and Gastric Cancer Patient
Status: COMPLETED
Conditions: Colorectal Cancer|Gastric Cancer|Chemotherapy-induced Peripheral Neuropathy
Interventions: OTHER: Hot compressing|OTHER: Cold compressing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Cognitive-based Prosthetics to Improve Grasp and Reaching After SCI
Status: COMPLETED
Conditions: Spinal Cord Injuries|Hand Weakness
Interventions: DEVICE: Cognition glove|DEVICE: Sensory brace
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Auricular Acupuncture on Fatigue, Energy and Well-Being in Intensive Care Nurses
Status: COMPLETED
Conditions: Fatigue
Interventions: OTHER: Auricular acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of Coltect (Selenium, Curcumin and Green Tea) on Irritable Bowel Syndrome
Status: UNKNOWN
Conditions: Irritable Bowel Syndrome
Interventions: DIETARY_SUPPLEMENT: coltect|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Probiotics on Gut Microbiota Composition and Metabolic Outcomes in Post- Gestational Diabetes Women
Status: COMPLETED
Conditions: Gestational Diabetes
Interventions: DIETARY_SUPPLEMENT: Probiotics|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of Stent-Related Symptoms Between Anti-Reflux Stents and Standard DJ Stents in Children With Urolithiasis
Status: NOT_YET_RECRUITING
Conditions: Urolithiasis|Child, Only
Interventions: DEVICE: LaiKai anti-reflux ureteral stent|DEVICE: LaiKai Ureteral Stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: STOP OA: A PILOT STUDY (GLA:D Canada) - Education and Targeted, Personalized Exercise for Hip and Knee Osteoarthritis
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: BEHAVIORAL: GLA:D Canada (education and neuromuscular exercise program)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Two Community-based Mental Health Interventions for Violence-Displaced Afro-Descendants in Colombia.
Status: COMPLETED
Conditions: Post-Traumatic Stress Disorder|Depression|Anxiety|Violence
Interventions: BEHAVIORAL: Common Elements Treatment Approach|BEHAVIORAL: Narrative Community Group Therapy|OTHER: Standby group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of the Brainsway Deep Transcranial Magnetic Stimulation (TMS) H-Coil in the Treatment of Major Depression Disorder
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DEVICE: Brainsway H-Coil Deep TMS System|DEVICE: Brainsway H-Coil Deep TMS System (Sham treatment)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: EFFECT OF Salvia Hispanica l. (CHIA) IN THE BIOCHEMICAL METABOLIC SYNDROME COMPONENTS
Status: UNKNOWN
Conditions: Metabolic Syndrome X
Interventions: DIETARY_SUPPLEMENT: Chia|DIETARY_SUPPLEMENT: Oatmeal|BEHAVIORAL: Normocaloric diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Evaluate Safety, Reactogenicity and Immunogenicity of GSK Biologicals' RSV Investigational Vaccine Based on Viral Proteins Encoded by Chimpanzee-derived Adenovector (ChAd155-RSV) (GSK3389245A) in RSV-seropositive Infants
Status: COMPLETED
Conditions: Respiratory Syncytial Virus Infections
Interventions: BIOLOGICAL: RSV (GSK3389245A) low dose formulation vaccine|BIOLOGICAL: RSV (GSK3389245A) middle dose formulation vaccine|BIOLOGICAL: RSV (GSK3389245A) high dose formulation vaccine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of agenT-797 in Combination With Botensilimab, Balstilimab, Ramucirumab, and Paclitaxel for People With Esophageal, Gastric, or Gastro-esophageal Junction Cancer
Status: RECRUITING
Conditions: Metastatic Esophageal Carcinoma|Advanced Unresectable Gastric Adenocarcinoma|Metastatic Gastric Cancer|Metastatic Gastroesophageal Junction Adenocarcinoma|Metastatic Esophageal Cancer|Metastatic Esophageal Adenocarcinoma|Metastatic Gastric Adenocarcinoma|Metastatic Gastric Carcinoma|Unresectable Esophageal Cancer|Unresectable Esophageal Adenocarcinoma|Unresectable Gastric Carcinoma|Unresectable Gastric Adenocarcinoma|Unresectable Gastroesophageal Junction Adenocarcinoma
Interventions: BIOLOGICAL: AgenT-797|BIOLOGICAL: Botensilimab|DRUG: Balstilimab|DRUG: Ramucirumab|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Cardiac Function Between Left Bundle Branch Pacing and Right Ventricular Outflow Tract Septal Pacing in Pacemaker-dependent Patients
Status: COMPLETED
Conditions: Slow Arrhythmia; Left Bundle Branch Pacing; Cardiac Function
Interventions: DEVICE: pacemaker
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of Targeted Radiation Therapy in People With Non-Small Cell Lung Cancer (NSCLC)
Status: RECRUITING
Conditions: Non Small Cell Lung Cancer|Non Small Cell Lung Cancer Metastatic|Non-small Cell Carcinoma|NSCLC|NSCLC Stage IV
Interventions: RADIATION: L-SABR|BIOLOGICAL: Anti-PD-(L)1 based immunotherapy|DRUG: Platinum based chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Virtual Home-based Physical Pre-habilitation in Kidney Transplant Candidates
Status: NOT_YET_RECRUITING
Conditions: Kidney Disease, End-Stage|Frailty|Transplant;Failure,Kidney
Interventions: OTHER: Intervention Group: Exercise and education.|OTHER: Usual Care Only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: COld Exposure With Controlled BReathing And Meditation in Patients With Multiple Sclerosis (COBRAMS)
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Sclerosis
Interventions: COMBINATION_PRODUCT: Wim Hoff method
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Standing on Non-Ambulatory Children With Neuromuscular Conditions
Status: COMPLETED
Conditions: Osteopenia|Spinal Muscular Atrophy|Cerebral Palsy|Muscular Dystrophy|Spina Bifida|Rett Syndrome
Interventions: OTHER: Assisted Standing Treatment Program
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vascular Endothelial Growth Factor (VEGF) Trap-Eye: Investigation of Efficacy and Safety in Central Retinal Vein Occlusion (CRVO)
Status: COMPLETED
Conditions: Retinal Vein Occlusion
Interventions: BIOLOGICAL: Aflibercept Injection (EYLEA, VEGF Trap-Eye, BAY86-5321)|OTHER: Sham treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation Glizigen® and Ocoxin®-Viusid® in High-grade Cervical Intraepithelial Lesions
Status: RECRUITING
Conditions: Carcinoma|Neoplasia; Intraepithelial, Cervix|Glandular Neoplasms|Epithelial Neoplasm|Neoplasms
Interventions: DIETARY_SUPPLEMENT: Glizigen® + Ocoxin-Viusid®
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of BMS-986256 at Steady State on the Single Dose Pharmacokinetics of Mycophenolate Mofetil
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DRUG: BMS-986256|DRUG: Mycophenolate Mofetil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Biomarkers in Depressed Inpatients Receiving Accelerated rTMS
Status: WITHDRAWN
Conditions: Depression
Interventions: DEVICE: repetitive transcranial magnetic stimulation (MagPro X100).|DEVICE: Intermittent Theta burst stimulation ( iTBS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Probiotics for Prevention Neonatal Infection
Status: TERMINATED
Conditions: Neonatal Sepsis|Sepsis|Neonatal Infections
Interventions: DIETARY_SUPPLEMENT: Synbiotics|DIETARY_SUPPLEMENT: Maltodextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Lapatinib in Treating Patients With Persistent or Recurrent Ovarian Epithelial or Peritoneal Cancer
Status: COMPLETED
Conditions: Primary Peritoneal Cavity Cancer|Recurrent Ovarian Epithelial Cancer
Interventions: DRUG: lapatinib ditosylate|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pediatric Bipolar Depression
Status: COMPLETED
Conditions: Bipolar Depression
Interventions: DRUG: Quetiapine XR|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transcranial Magnetic Stimulation for MCI
Status: RECRUITING
Conditions: Mild Cognitive Impairment|Depression
Interventions: DEVICE: Accelerated iTBS|DEVICE: Sham Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Bupropion Versus Bupropion + Naltrexone for Smoking Cessation
Status: UNKNOWN
Conditions: Tobacco Use Disorder
Interventions: DRUG: Bupropion|DRUG: Bupropion + Naltrexone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of the 7 Days Tailored Therapy as 2nd Rescue Therapy for Eradication of H. Pylori Infection
Status: TERMINATED
Conditions: Helicobacter Infection
Interventions: PROCEDURE: H. pylori culture and antimicrobial susceptibility testing|DRUG: 14 days empirical bismuth quadruple therapy (Proton pump inhibitor)|DRUG: Metronidazole|DRUG: Tetracycline|DRUG: tripotassium dicitrate bismuthate|DRUG: 7 days tailored therapy Proton Pump Inhibitor|DRUG: Moxifloxacin|DRUG: Amoxicillin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Humanized CAR-T Cells of Anti-BCAM and Anti-CD19 Against Relapsed and Refractory Multiple Myeloma
Status: UNKNOWN
Conditions: Relapsed or Refractory Multiple Myeloma
Interventions: BIOLOGICAL: Autologous BCMA CAR-T cells and CD19 CAR-T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Parent Training to Reduce Behavioral Problems in Children With Autism Spectrum Disorder in China
Status: COMPLETED
Conditions: Child Behavior Problem|Autism Spectrum Disorder|Parent-Child Relations|Parenting|Mental Health Issue|Child Abuse|Family Relations
Interventions: BEHAVIORAL: Stars and Rain Education Institute for Autism (SREIA) Parent Training Programme
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Volar Locking Plate vs Fragment Specific Fixation in Wrist Fractures
Status: COMPLETED
Conditions: Distal Radius Fractures
Interventions: PROCEDURE: Open reduction and fixation with TriMed fragment-specific system|PROCEDURE: Open reduction and fixation with TriMed volar locking plate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immune Reconstitution of Immunosuppressed Sepsis Patients
Status: TERMINATED
Conditions: Severe Sepsis With Septic Shock
Interventions: DRUG: Interleukin-7|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigation of the Genetic and Environmental Determinants of MP Including Response to Supplementation
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Nutrof Total|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Transcranial Focused Ultrasound on Human Primary Motor Cortex Using 7T fMRI
Status: COMPLETED
Conditions: Ultrasound in MRI
Interventions: OTHER: Focused Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety and Efficacy of Different Oral Doses of BAY94-8862 in Subjects With Type 2 Diabetes Mellitus and the Clinical Diagnosis of Diabetic Nephropathy
Status: COMPLETED
Conditions: Diabetic Nephropathies
Interventions: DRUG: Finerenone (BAY94-8862)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: FES (16α-[18F]-Fluoro-17β-estradiol)-PET: Towards a New Standard to Stage Locally Advanced and Recurrent, Estrogen Receptor Positive (ER+) Breast Cancer? Pilot Study to Compare [18F]FES-PET and [18F]FDG-PET
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DIAGNOSTIC_TEST: 18F-Fluorestradiol PET/CT scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Treatment With Tamoxifen in Cryptococcal Meningitis
Status: COMPLETED
Conditions: Meningitis Streptococcal|Hiv|Meningitis|Meningoencephalitis
Interventions: DRUG: Tamoxifen|DRUG: Amphotericin B|DRUG: Fluconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Randomized Trial Comparing Urinary Diversion After Robot-assisted Radical Prostatectomy
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DEVICE: balloon catheter for suprapubic bladder-drainage|DEVICE: balloon catheter for transurethral bladder-drainage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Visual Function With Bilateral AcrySof® ReSTOR® Aspheric SN6AD1
Status: COMPLETED
Conditions: Cataract
Interventions: DEVICE: AcrySof ReSTOR Aspheric IOL model SN6AD1
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Postoperative Hypofractionated Radiation in Cervical and Endometrial Tumours: Phase II Study
Status: RECRUITING
Conditions: Cervical Cancer|Endometrial Cancer
Interventions: RADIATION: Hypofractionated Image guided External Beam Radiation Therapy (EBRT)|DRUG: Cisplatin|RADIATION: Vaginal brachytherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: (PET) Imaging in the Management of Patients With Solitary Pulmonary Nodules
Status: COMPLETED
Conditions: Benign and Malignant Solitary Pulmonary Nodules
Interventions: PROCEDURE: PET Imaging|PROCEDURE: CT scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Metabolic Cofactor Supplementation in Alzheimer's Disease (AD) and Parkinson's Disease (PD) Patients
Status: COMPLETED
Conditions: Alzheimer Disease|Parkinson Disease
Interventions: DRUG: Metabolic Cofactor Supplementation|DRUG: Sorbitol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: AcuTA: Acupuncture in Test Anxiety
Status: COMPLETED
Conditions: Test Anxiety|Experimental Setting (Trier Social Stress Test TSST)
Interventions: DEVICE: Acupuncture|DEVICE: Laser Acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Cell Therapy in Patients With Chronic Ischemic Heart Disease Undergoing Cardiac Surgery
Status: UNKNOWN
Conditions: Old Myocardial Infarction|Chronic Myocardial Ischemia|Left Ventricular Dysfunction
Interventions: PROCEDURE: bone marrow mononuclear cells injection|PROCEDURE: placebo intramyocardial injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Lumber Spine Mobilization and Spinal Traction on Lumber Radiculopathy.
Status: COMPLETED
Conditions: Lumbar Radiculopathy
Interventions: OTHER: SMWLM combined Spinal traction with belt|OTHER: SMWLM combined spinal traction without belt
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Development and Application of a New Balloon Catheter for Intraairway Hemostasis
Status: UNKNOWN
Conditions: Hemoptysis
Interventions: DEVICE: a New Balloon Catheter for Intraairway Hemostasis|DEVICE: Traditional Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 1a/1b FIH Study of PY159 and in Combination With Pembrolizumab in Subjects With Advanced Solid Tumors
Status: TERMINATED
Conditions: Advanced Solid Tumor|Gynecologic Cancer|Breast Cancer|Colorectal Cancer|Gastric Adenocarcinoma|Lung Adenocarcinoma|Pancreatic Cancer|Head and Neck Cancer
Interventions: DRUG: PY159 Single agent dose level 1|DRUG: PY159 Single agent dose level 2|DRUG: PY159 Single agent dose level 3|DRUG: PY159 Single agent dose level 4|DRUG: PY159 Single agent dose level 5|DRUG: PY159 Single agent dose level 6|DRUG: PY159 Single agent dose level 7|DRUG: PY159/Pembrolizumab Combination dose level 1|DRUG: PY159/Pembrolizumab Combination dose level 2|DRUG: PY159/Pembrolizumab Combination dose level 3|DRUG: PY159/Pembrolizumab Combination dose level 4|DRUG: PY159 Single agent dose expansion cohort|DRUG: PY159/Pembrolizumab Combination dose expansion cohort 1|DRUG: PY159/Pembrolizumab Combination dose expansion cohort 2|DRUG: PY159/Pembrolizumab Combination dose expansion cohort 3|DRUG: PY159/Pembrolizumab Combination dose expansion cohort 4|DRUG: PY159/Pembrolizumab Combination dose expansion cohort 5|DRUG: PY159/Pembrolizumab Combination dose expansion cohort 6
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Effect of Magnesium Sulfate and Dexamethasone on Postoperative Sore Throat After Spinal Surgery in Prone Position With Tracheal Intubation: a Double-blind, Randomized, Noninferiority Clinical Trial
Status: COMPLETED
Conditions: Post Operative Sore Throat
Interventions: DRUG: Magnesium Sulfate|DRUG: dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Recurrent GBM With Maximal Neurosurgical Removal and Treatment With IORT
Status: TERMINATED
Conditions: Glioblastoma|GBM|Recurrent GBM
Interventions: RADIATION: Intra-operative Radiation Therapy - IORT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Temozolomide Alone or With Pegylated Interferon-Alpha 2b (PGI) in Melanoma Patients
Status: COMPLETED
Conditions: Melanoma
Interventions: DRUG: Temozolomide (TMZ)|DRUG: Pegylated Interferon Alpha-2b (PGI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of Stellate Ganglion Block on Postoperative Nausea and Vomiting
Status: RECRUITING
Conditions: Stellate Ganglion Block|Thyroid Surgery|Postoperative Nausea and Vomiting
Interventions: PROCEDURE: Right -stellate ganglion block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Paclitaxel Eluting Balloon Versus Drug Eluting Stent in Native Coronary Artery Stenoses of Diabetic Patients
Status: COMPLETED
Conditions: Coronary Stenosis|Diabetes Mellitus
Interventions: DEVICE: Paclitaxel Eluting Balloon|DEVICE: paclitaxel eluting stent|DEVICE: bare metal stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Social-emotional and Behavioural Problems of Healthcare Workers During the Outbreak
Status: COMPLETED
Conditions: Emotional Disorder of Childhood
Interventions: DIAGNOSTIC_TEST: Brief Infant-Toddler Social and Emotional Assessment (BITSEA) questionnaire|DIAGNOSTIC_TEST: Brief Infant Sleep Questionnaire (BISQ) questionnaire|DIAGNOSTIC_TEST: Multidimensional Scale of Perceived Social Support (MSPSS) questionnaire|DIAGNOSTIC_TEST: Brief Symptom Inventory (BSI) questionnaire
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: PK Interaction Between Rifapentine or Rifampicin and a Single Dose of TMC207 in Healthy Subjects (TMC207-CL002)
Status: COMPLETED
Conditions: Tuberculosis
Interventions: DRUG: TMC207|DRUG: rifapentine|DRUG: rifampicin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Amifostine With IMRT for Submandibular and Sublingual Salivary Sparing During Head and Neck Cancer Treatment
Status: TERMINATED
Conditions: Head and Neck Cancer
Interventions: DRUG: Amifostine|PROCEDURE: Intensity- Modulated Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Drug-Drug Interaction Study Between Colchicine and Cyclosporine
Status: COMPLETED
Conditions: Pharmacokinetics|Healthy
Interventions: DRUG: Colchicine|DRUG: Cyclosporine|DRUG: Colchicine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: High-Dose Isoniazid Among Adult Patients With Different Genetic Variants of INH-Resistant Tuberculosis (TB)
Status: COMPLETED
Conditions: Tuberculosis
Interventions: DRUG: Isoniazid|DIETARY_SUPPLEMENT: Vitamin B6
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cannabidiol for Postoperative Opioid Reduction in Primary Total Knee Arthroplasty
Status: RECRUITING
Conditions: Knee Replacement Surgery|Osteoarthritis, Knee
Interventions: DRUG: Epidiolex oral solution|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: AMD3100 (Plerixafor) With G-CSF in Poor Mobilizing Adult Patients Who Previously Failed Hematopoietic Stem Cell (HSC) Collection/Attempts
Status: COMPLETED
Conditions: Autologous Stem Cell Transplantation
Interventions: DRUG: G-CSF plus plerixafor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Acupuncture on Chemotherapy-Induced Peripheral Neuropathy
Status: UNKNOWN
Conditions: Chemotherapy-Induced Peripheral Neuropathy (CIPN)
Interventions: OTHER: acupuncture|OTHER: minimal acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: FB101 Intervention in Women Screened to Have Vaginal Dysbiosis
Status: COMPLETED
Conditions: Vaginal Flora Imbalance
Interventions: OTHER: FB101|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Body Posture and the Stomatognathic System of School-age Children
Status: UNKNOWN
Conditions: Postural; Defect|Stomatognathic System Abnormalities|Malocclusion
Interventions: DIAGNOSTIC_TEST: Research Diagnostic Criteria of Functional Disorders of the Masticatory System BKD / ZCURNŻ - Polish version|DEVICE: Clinical examination of the stomatognathic system (structural and functional)|DEVICE: 3D examination of the body posture|DEVICE: Functional assessment of the spine and lower limbs|DEVICE: Complementary tests
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparing the Effects of Neck Stabilization Exercises Verses Dynamic Exercises Among Patients Having Nonspecific Neck Pain With Forward Head Posture
Status: COMPLETED
Conditions: Non-specific Neck Pain
Interventions: OTHER: Stabilization exercises|OTHER: Dynamic exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Coenzyme Q10 and Selenium on Seminal Fluid and Semen Antioxidant Status
Status: COMPLETED
Conditions: Male Infertility
Interventions: DIETARY_SUPPLEMENT: Coenzyme Q10|DIETARY_SUPPLEMENT: Selenium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non-inferiority Study of the Effect of Non-cooling Blanket on Body Temperature in Patients With Heat Stroke
Status: RECRUITING
Conditions: Heat Stroke
Interventions: DEVICE: cooling blanket|DEVICE: non-cooling blanket
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Optimization of Vonoprazan--amoxicillin Dual Therapy for Eradicating Helicobacter Pyloriinfection
Status: COMPLETED
Conditions: Helicobacter Pylori Eradication Rate
Interventions: DRUG: vonoprazan fumarate + high dose amoxicillin（H-10d）|DRUG: vonoprazan fumarate + low dose amoxicillin（L-10d)|DRUG: vonoprazan fumarate + amoxicillin（H-14d)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intermittent Therapy in Metastatic Renal Cell Carcinoma Patients Treated With Ipilimumab and Nivolumab
Status: COMPLETED
Conditions: Metastatic Renal Cell Carcinoma
Interventions: DRUG: Nivolumab|DRUG: Ipilimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Cognitive Rehab and Physical Activity on Cognition in Patients With Metastatic Brain Tumors Undergoing RT
Status: TERMINATED
Conditions: Metastatic Brain Tumor|Cerebral Metastases
Interventions: BEHAVIORAL: Physical Activity|BEHAVIORAL: Cognitive rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: HIV Vaccine Study in HIV Positive Patients
Status: COMPLETED
Conditions: HIV Infections
Interventions: BIOLOGICAL: HIV-v (Low Dose)|BIOLOGICAL: HIV-v (High Dose)|BIOLOGICAL: HIV-v (Control)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Mechanical Interference Versus Neural Mobilization on Ulnar Neuropathy Post Cubital Tunnel Syndrome
Status: NOT_YET_RECRUITING
Conditions: Cubital Tunnel Syndrome
Interventions: OTHER: Mechanical interference|OTHER: Neural mobilization|OTHER: conventional treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Influenza Vaccination for Flu Prevention in Patients With Plasma Cell Disorders
Status: COMPLETED
Conditions: Plasma Cell Neoplasm
Interventions: BIOLOGICAL: Pneumococcal 13-valent Conjugate Vaccine|BIOLOGICAL: Trivalent Influenza Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Remote Ischemic Conditioning With Local Ischemic Postconditioning in High-Risk ST-elevation Myocardial Infarction
Status: RECRUITING
Conditions: ST Elevation Myocardial Infarction
Interventions: PROCEDURE: RIC + PostC + Standard PCI|PROCEDURE: Standard PCI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Prosthesis Training on Pain, Prosthesis Satisfaction and Ambulatory Status of Lower Limb Amputees
Status: RECRUITING
Conditions: Lower Limb Amputation Below Knee (Injury)
Interventions: OTHER: Prosthesis Training|OTHER: Phantom Exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of ALLO-316 in Subjects With Advanced or Metastatic Clear Cell Renal Cell Carcinoma
Status: RECRUITING
Conditions: Advanced/Metastatic Clear Cell Renal Cell Carcinoma
Interventions: GENETIC: ALLO-316|BIOLOGICAL: ALLO-647|DRUG: Fludarabine|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endovascular Treatment for Mild Ischemic Stroke Due to Acute Large Vessel Occlusion in the Anterior Circulation
Status: RECRUITING
Conditions: Endovascular Treatment|Mild Stroke
Interventions: PROCEDURE: EVT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Assessing the Efficacy of CARDIOgoniometry (CGM) to Determine Physiologically Significant Stenosis in Patients With Stable Coronary Artery Disease in Comparison to Fractional FLOW Reserve - CARDIOFLOW
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DEVICE: Cardiogoniometry (CGM)|DEVICE: Fractional Flow Reserve (FFR)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Assessing Open Access Audio
Status: COMPLETED
Conditions: Hypertension|Diabetes
Interventions: OTHER: Open Access Audio|OTHER: No Access, Patient and Provider Aware of Recording|OTHER: No Access, Provider Unaware of Recording
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Single-dose Study of Octreotide Injection in Healthy Adult Subjects
Status: COMPLETED
Conditions: Acromegaly
Interventions: DRUG: SYHX2008 injection|DRUG: Octreotide Acetate Microspheres for Injection injection|DRUG: Sandostatin ® injection|DRUG: Placebo to SYHX2008 injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Indapamide Versus Hydrochlorothiazide in Elderly Hypertensive Patients With Renal Insufficiency
Status: COMPLETED
Conditions: Hypertension|Renal Insufficiency
Interventions: DRUG: Indapamide|DRUG: Hydrochlorothiazide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combined Tooth-implant Supported Prostheses
Status: COMPLETED
Conditions: Dental Implant|Short Dental Implant
Interventions: PROCEDURE: Insertion of 1 Nucleoss T4 dental implants in posterior mandible|PROCEDURE: Insertion of 1 Nucleoss T5 dental implants in posterior mandible|PROCEDURE: Insertion of 2 Nucleoss T4 dental implants posterior mandible
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Infection Rates of Myeloablative Allo SCT Recipients Receiving Neutropenic Diets Versus Non-Neutropenic Diets
Status: COMPLETED
Conditions: Hematologic Malignancies
Interventions: OTHER: Non-neutropenic Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Communication Strategy to PROMOTE HPV Vaccination in Pharmacies: PROMOTE Study
Status: COMPLETED
Conditions: Human Papillomavirus Infection
Interventions: OTHER: Communication Intervention|OTHER: Communication Skills Training|BEHAVIORAL: Healthcare Activity|BEHAVIORAL: Healthcare Activity|OTHER: Survey Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Semaglutide Treatment for Hyperglycaemia After Renal Transplantation
Status: RECRUITING
Conditions: Hyperglycemia|Renal Transplant Complication Primary Non-Function|Diabetes
Interventions: DRUG: Semaglutide 14 MG [Rybelsus]|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Efficacy and Safety of S303 Treated Red Blood Cells (RBCs)in Subjects With Thalassemia Major Requiring Chronic RBC Transfusion
Status: COMPLETED
Conditions: Thalassemia Major
Interventions: BIOLOGICAL: S-303 Treated Red Blood Cells (RBCs)|BIOLOGICAL: Conventional, untreated Red Blood Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: DAILIES® AquaComfort Plus® Multifocal (MF) - Comparative Assessment of Visual Performance
Status: COMPLETED
Conditions: Presbyopia|Refractive Error
Interventions: DEVICE: Nelfilcon A MF contact lenses (DACP MF)|DEVICE: Nelfilcon A single vision contact lenses (DACP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of CoQ10 During One Cycle of Doxorubicin Treatment for Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: CoQ10|OTHER: CoQ10 Placebo|DRUG: Doxorubicin|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Evaluate Pembrolizumab Plus Lenvatinib in PD-L1 Positive TKI Resistant NSCLC Patients
Status: UNKNOWN
Conditions: NSCLC
Interventions: DRUG: Pembrolizumab|DRUG: Lenvatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral Glucocorticosteroid in the Treatment of Severe Asthma Exacerbation in Hospitalized Patients
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: methylprednisolone sodium succinate (mPSL)|DRUG: prednisolone (PSL)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ointment Therapy and Prevention of Cannulation-Induced Superficial Phlebitis
Status: UNKNOWN
Conditions: Phlebitis
Interventions: DRUG: Nitroglycerin ointment|DRUG: Clobetasol Topical
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Pulsed RF Neuromodulation and Leukocyte-Rich PRP for Refractory Low Back Pain
Status: RECRUITING
Conditions: Multi-Organ Disorder
Interventions: PROCEDURE: Pulsed RF Neuromodulation|BIOLOGICAL: Leukocyte-Rich PRP Injection|PROCEDURE: Physiotherapy Alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Gabapentin in Prevention of Tourniquet Pain and Hypertension
Status: WITHDRAWN
Conditions: Tourniquet-induced Pain|Tourniquet-induced Hypertension
Interventions: DRUG: gabapentin 600 mg po|DRUG: Placebo pill given one hour before surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Eye Movement on Toric Lens Orientation and Visual Acuity
Status: COMPLETED
Conditions: Astigmatism
Interventions: DEVICE: senofilcon A|DEVICE: balafilcon A|DEVICE: omafilcon A|DEVICE: lotrafilcon B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Day Case Laparoscopic Cholecystectomy: Fundus First With Ultrasonic Dissection or Conventional Diathermy Hook
Status: COMPLETED
Conditions: Cholecystolithiasis
Interventions: PROCEDURE: dissection of gallbladder in laparoscopic cholecystectomy|PROCEDURE: dissection of gallbladder in laparoscopic cholecystectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Acid Lactase in Combination With Yoghurt Bacteria for Improvement of Lactose Digestion in Lactose Malabsorbers
Status: COMPLETED
Conditions: Lactose Malabsorption
Interventions: DIETARY_SUPPLEMENT: Acid lactase|DIETARY_SUPPLEMENT: Acid lactase|DIETARY_SUPPLEMENT: Lyoph. yoghurt bacteria|DIETARY_SUPPLEMENT: Acid lactase plus yoghurt bacteria|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized Clinical Trial Comparing Executive Function and Language Skills Training on School Readiness in Preschool Children
Status: COMPLETED
Conditions: Executive Function|Language|Preschool Child
Interventions: BEHAVIORAL: Executive functions training|BEHAVIORAL: Language skills training|OTHER: Regular school curriculum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Personalized Versus Standard Hydration for Prevention of CI-AKI: a Randomized Trial With Bioimpedance Analysis
Status: COMPLETED
Conditions: Acute Kidney Injury
Interventions: DRUG: sodium chloride infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Impact of Counseling and Education on Opioid Consumption After ACL Reconstruction
Status: ACTIVE_NOT_RECRUITING
Conditions: Pain, Postoperative|Opioid Use
Interventions: BEHAVIORAL: Perioperative Pain Management Education and Counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study FFR116365, an Open-label Study of GW685698X in Paediatric Subjects With Perennial Allergic Rhinitis
Status: COMPLETED
Conditions: Rhinitis
Interventions: DRUG: Fluticasone furoate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rituximab and Hyaluronidase Human in Patients With Advanced Melanoma Undergoing Nivolumab and Ipilimumab Therapy
Status: ACTIVE_NOT_RECRUITING
Conditions: Cutaneous Melanoma, Stage III|Cutaneous Melanoma, Stage IV|Stage III Melanoma|Stage IIIA Skin Melanoma|Stage IIIB Skin Melanoma|Stage IIIC Skin Melanoma|Stage IV Skin Melanoma|Unresectable Melanoma
Interventions: DRUG: Nivolumab|BIOLOGICAL: Rituximab and Hyaluronidase Human|DRUG: Ipilimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PPIs and Gastroesophageal Varices in Liver Cirrhosis (PPIs: Proton Pump Inhibitors)
Status: COMPLETED
Conditions: Liver Cirrhosis|Hypertension, Portal
Interventions: DRUG: Proton Pump Inhibitors|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effective Strategies for Dementia Care
Status: COMPLETED
Conditions: Dementia|Cognitive Impairment
Interventions: BEHAVIORAL: Snoezelen ©|BEHAVIORAL: structured reminiscence therapy|BEHAVIORAL: 10-minutes activation|BEHAVIORAL: Unstructured verbal communication
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Evaluation and Treatment of Elevated Left-Sided Filling Pressures by Balloon Inflation Within the IVC
Status: UNKNOWN
Conditions: Hypertension, Pulmonary|Heart Failure
Interventions: PROCEDURE: Preventing pulm HTN during exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Evaluate the Safety and Tolerability of Oral Ixazomib in Scleroderma-related Lung Disease Patients
Status: TERMINATED
Conditions: Systemic Sclerosis|Scleroderma|Diffuse Systemic Sclerosis|Diffuse Scleroderma|Diffuse Cutaneous Systemic Sclerosis|Diffuse Cutaneous Scleroderma|Progressive Systemic Sclerosis|Progressive Scleroderma|Scleroderma, Systemic|Scleroderma, Diffuse|Scleroderma;Progressive|Systemic Sclerosis, Diffuse|Systemic; Sclerosis, Progressive|Scleroderma of Lung|Scleroderma With Pulmonary Involvement|Systemic Sclerosis Pulmonary|Systemic Sclerosis With Lung Involvement|Interstitial Lung Disease|Pulmonary Fibrosis Interstitial
Interventions: DRUG: Ixazomib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunotherapy Using Lenalidomide + Bystander Vaccine in High Risk Myelodysplastic Syndrome (MDS)
Status: COMPLETED
Conditions: Leukemia
Interventions: DRUG: lenalidomide|BIOLOGICAL: bystander vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RTA 408 Capsules in Patients With Melanoma - REVEAL
Status: COMPLETED
Conditions: Melanoma|Unresectable (Stage III) Melanoma|Metastatic (Stage IV) Melanoma
Interventions: DRUG: Omaveloxolone Capsules (2.5 mg/capsule)|DRUG: Ipilimumab (3 mg/kg)|DRUG: Nivolumab (240 mg)|DRUG: Omaveloxolone Capsules (10 mg/capsule)|DRUG: Omaveloxolone Capsules (50 mg/capsule)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ethanol and Cannabinoid Effects on Simulated Driving and Related Cognition: Substudy III
Status: ACTIVE_NOT_RECRUITING
Conditions: Cannabis|Alcohol Effect|Driving Under the Influence of Alcohol and Other Drugs
Interventions: DRUG: Active Dronabinol|DRUG: Placebo|DRUG: Placebo|DRUG: Active Ethanol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study Comparing Two Alternatives of Antiretroviral Therapy as Post-exposure Prophylaxis to HIV-1: Tenofovir + Emtricitabine + Lopinavir/Ritonavir Versus Tenofovir + Emtricitabine + Raltegravir (RAL-PEP)
Status: COMPLETED
Conditions: HIV Infection
Interventions: DRUG: Tenofovir, Emtricitabine, Lopinavir/r|DRUG: Tenofovir, Emtricitabine, Raltegravir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Preparing Older Veterans With Serious and Chronic Illness for Decision Making
Status: COMPLETED
Conditions: Aging
Interventions: BEHAVIORAL: PREPARE website|BEHAVIORAL: Advance directive
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Clinical Trial of SB-509 in Subjects With Diabetic Neuropathy
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1|Diabetes Mellitus, Type 2|Diabetic Polyneuropathy
Interventions: BIOLOGICAL: SB-509|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Supervised Group Exercise and Home Exercise Program for Knee Osteoarthritis
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: OTHER: Supervised group exercise|OTHER: Home-based exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT