pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: FIM-BR - First-in-Man Study (Brazil Part) With Sirolimus-Coated BX VELOCITY Stent
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DEVICE: sirolimus coated Bx VELOCITY stent - fast release|DEVICE: sirolimus coated Bx VELOCITY stent - slow release
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Etoposide-Carboplatin Alone or With Endostar for Extensive Disease Small Cell Lung Cancer (ED-SCLC)
Status: COMPLETED
Conditions: Small Cell Lung Cancer
Interventions: DRUG: Endostar|DRUG: Etoposide-Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Systematic Screening for Deep Vein Thrombosis in Critically Ill Patients
Status: UNKNOWN
Conditions: Deep Vein Thrombosis
Interventions: DIAGNOSTIC_TEST: Ultrasound examination of lower limb veins
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: INSPIRON Sirolimus Eluting Stent Performance in Bifurcation Coronary Arteries Treated Using Provisional Technique
Status: UNKNOWN
Conditions: Bifurcation Lesion|Coronary Artery Disease
Interventions: DEVICE: Inspiron Sirolimus Eluting Stent
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Fresh, Frozen or Lyophilized Fecal Microbiota Transplantation for Multiple Recurrent C. Difficile Associated Diarrhea
Status: COMPLETED
Conditions: Recurrent C. Difficile Associated Diarrhea
Interventions: BIOLOGICAL: Fecal Microbiota
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optune for Children With High-Grade Glioma or Ependymoma, and Optune With Radiation Therapy for Children With DIPG
Status: RECRUITING
Conditions: Malignant Glioma|Ependymoma|Diffuse Intrinsic Pontine Glioma
Interventions: DEVICE: Optune System (NovoTTF-200A System, Tumor Treating Fields, TTFields)|COMBINATION_PRODUCT: Concurrent Optune and RT followed by Optune System alone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A First-In-Human Study of Single and Multiple Ascending Doses of Oral SUL-238 in Healthy Subjects
Status: RECRUITING
Conditions: Healthy Subjects
Interventions: DRUG: Single ascending doses SUL-238|DRUG: Single dose Placebo|DRUG: Single dose SUL-238|DRUG: Multiple ascending doses SUL-238|DRUG: Multiple doses Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Transjugular Intraheptic Portosystemic Shunt (TIPS) on Gastrointestinal Motility and the Gut Microbiota
Status: COMPLETED
Conditions: Cirrhosis
Interventions: DIAGNOSTIC_TEST: SMART Pill Pre-TIPS|DIAGNOSTIC_TEST: SMART Pill Post TIPS
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of HGF Via Plasmid Vector to Improve Perfusion in Critical Limb Ischemia
Status: COMPLETED
Conditions: Arterial Occlusive Disease|Peripheral Vascular Disease|Ischemia
Interventions: GENETIC: HGF plasmid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of INT-747 in Patients With Diabetes and Presumed NAFLD
Status: COMPLETED
Conditions: Diabetes Mellitus, Type II|Fatty Liver
Interventions: DRUG: INT-747|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy, Total Body Irradiation, and Donor Blood Stem Cell Transplant in Treating Patients With Secondary Myelofibrosis
Status: RECRUITING
Conditions: Secondary Myelofibrosis
Interventions: PROCEDURE: Allogeneic Hematopoietic Stem Cell Transplantation|DRUG: Cyclophosphamide|DRUG: Fludarabine|BIOLOGICAL: Glycosylated Recombinant Human G-CSF AVI-014|OTHER: Laboratory Biomarker Analysis|DRUG: Melphalan|DRUG: Mycophenolate Mofetil|DRUG: Tacrolimus|RADIATION: Total-Body Irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low Field Magnetic Stimulation (LFMS) in Subjects With Treatment-Resistant Depression (TRD)
Status: COMPLETED
Conditions: Depression|Depressive Disorder|Depressive Disorder, Treatment-resistant|Depressive Disorder, Major
Interventions: DEVICE: LFMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Escitalopram in PCOS
Status: COMPLETED
Conditions: Polycystic Ovary Syndrome
Interventions: DRUG: Escitalopram 20 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Chemoprevention Trial in Familial Adenomatous Polyposis (FAP) Coli Using EPA
Status: COMPLETED
Conditions: Familial Adenomatous Polyposis Coli|FAP
Interventions: DRUG: Eicosapentanoic Acid (EPA)|PROCEDURE: Endoscopy|PROCEDURE: Biopsies taken|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effectiveness of Intensive Training in Upper Limb Rehabilitation After Stroke.
Status: ACTIVE_NOT_RECRUITING
Conditions: Stroke
Interventions: DEVICE: Intensive training with robotic exoskeleton for upper limbs|DEVICE: Task specific training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of DS-8201a for Participants With Advanced Solid Malignant Tumors
Status: COMPLETED
Conditions: Neoplasm Metastasis
Interventions: DRUG: DS-8201a|DRUG: Ritonavir|DRUG: Itraconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Bio-mechanical Awareness and Core Stability Exercises on Mechanical Low Back Pain
Status: NOT_YET_RECRUITING
Conditions: Mechanical Low Back Pain
Interventions: OTHER: bio-mechanical awareness|OTHER: core stability exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Study to Test the Safety of Increasing Multiple Doses of BAY2328065 Given by Mouth, How the Drug is Tolerated and Acts in the Human Body of Healthy Male Participants. Alteration of the Study Drug Effects by Another Drug and the Availability of the Drug Given in Different Formulations is Also Tested.
Status: COMPLETED
Conditions: Endometriosis
Interventions: DRUG: BAY2328065 LSF|DRUG: BAY2328065 tablet|DRUG: Placebo LSF|DRUG: Placebo tablet|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Quantitative EEG Changes Following Repetitive Transcranial Magnetic Stimulation in Patients With Post Stroke (EEG-rTMS)
Status: RECRUITING
Conditions: Stroke|Stroke, Ischemic|Stroke/Brain Attack
Interventions: DEVICE: repetitive Transcranial Magnetic Stimulation (rTMS)|OTHER: 32 electrode electroencephalography (EEG)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of AlignBabyCleft (ABaCleft)
Status: NOT_YET_RECRUITING
Conditions: Cleft Lip|Cleft Palate
Interventions: DEVICE: Appliance. Orthodontic appliance to carry out dentoalveolar movement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Effectiveness Research to Assess the Use of Primary ProphylacTic Implantable Cardioverter Defibrillators in Europe
Status: COMPLETED
Conditions: Coronary Artery Disease|Myocardial Infarction|Dilated Cardiomyopathy|Implantable Defibrillator User
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy of Prophylactic Fluconazole Therapy in Preterm and Very Low Birth Weight Neonates in Preventing Invasive Fungal Infection.
Status: COMPLETED
Conditions: Invasive Candidiases
Interventions: DRUG: Fluconazole|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Circadian Intraocular Pressure Patterns in Patients With Sleep Apnea Syndrome and Treatment With Continuous Air Pressure
Status: COMPLETED
Conditions: Obstructive Sleep Apnea
Interventions: DEVICE: SHAM Continuous positive airway pressure|DEVICE: Continuous positive airway pressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Comparative Tests of Flu Vaccination Phone Messages
Status: COMPLETED
Conditions: Influenza, Human
Interventions: BEHAVIORAL: Viral changes|BEHAVIORAL: Protect others|BEHAVIORAL: General intentions|BEHAVIORAL: Behavioral intentions|BEHAVIORAL: Accountability
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Biological Study of Resveratrol's Effects on Notch-1 Signaling in Subjects With Low Grade Gastrointestinal Tumors
Status: COMPLETED
Conditions: Neuroendocrine Tumor
Interventions: DIETARY_SUPPLEMENT: Resveratrol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 3-D Visualization of the Anti-Obstructive Effect of Levocetirizine
Status: COMPLETED
Conditions: Allergic Rhinitis
Interventions: DRUG: Levocetirizine|DRUG: Levocetirizine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impacts of Mechanistic Target of Rapamycin (mTOR) Inhibition on Aged Human Muscle (Rapamune)
Status: RECRUITING
Conditions: Muscle Atrophy|Age-Related Sarcopenia
Interventions: DRUG: Rapamune (sirolimus) 1Mg Tablet|BEHAVIORAL: Unilateral resistance exercise training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Single-Cell Map of Immune and Lymphoma Cells in B-cell Non-Hodgkin's Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Diffuse Large B-cell Lymphoma
Interventions: OTHER: Patient with histologically confirmed diffuse large B-cell lymphoma with a planned first line treatment by R-CHOP.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Hysteroscopic Suture Fixation of Mirena in the Treatment of Adenomyosis
Status: NOT_YET_RECRUITING
Conditions: Adenomyosis|Hysteroscopy
Interventions: PROCEDURE: A:hysteroscopic suture fixation of Mirena|PROCEDURE: A: simple Mirena placement under hysteroscopy|PROCEDURE: B: hysteroscopic suture fixation of Mirena|PROCEDURE: B：simple Mirena placement under hysteroscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: AI-Based Multimodal Multi-tasks Analysis Reveals Tumor Molecular Heterogeneity, Predicts Preoperative Lymph Node Metastasis and Prognosis in Papillary Thyroid Carcinoma
Status: RECRUITING
Conditions: Papillary Thyroid Carcinoma; Molecular Heterogeneity; Multi-model Analysis; Artificial Intelligence; Lymph Node Metastases; Disease-free Survival
Interventions: OTHER
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of the Effectiveness of the Remedee Solution in Fibromyalgia
Status: COMPLETED
Conditions: Fibromyalgia
Interventions: DEVICE: Immediate Remedee Solution|DEVICE: Delayed Remedee Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Safety Study Looking at the Combination of Velcade and G-CSF in Patients With Myeloma or Lymphoma
Status: COMPLETED
Conditions: Malignant Lymphoma, Stem Cell Type|Autologous Transplant
Interventions: DRUG: bortezomib and G-CSF
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of a Single Bout of Resistance Training Session on Hormonal Response in Pre-pubertal and Pubertal Boys
Status: UNKNOWN
Conditions: Hormones|Cytokines
Interventions: OTHER: Resistance Training
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Optimal Lidocaine Buffering to Reduce Injection Pain in Local Anesthesia
Status: TERMINATED
Conditions: Local Anesthesia
Interventions: DRUG: lidocaine|DRUG: sodium bicarbonate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase III Study in First-line Treatment of Patients With Metastatic Colorectal Cancer Who Are Not Candidate for Intensive Therapy.
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: Trifluridine/tipiracil hydrochloride (S95005)|DRUG: Capecitabine|BIOLOGICAL: Bevacizumab experimental|BIOLOGICAL: Bevacizumab control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Measurement of Myocardial Stiffness Using Elastometry in Patients With Aortic Stenosis
Status: RECRUITING
Conditions: Aortic Valve Stenosis
Interventions: DEVICE: Aixplorer Mach30
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Role Of Pregabalin To Decrease Postoperative Pain In Microdiscectomy
Status: COMPLETED
Conditions: Pain, Nerve|Prolapsed Intervertebral Disc
Interventions: DRUG: Pregabalin 75mg|DEVICE: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Efficacy and Safety of "On-demand" Maintenance Therapy With Rabeprazole in Patients With Non-erosive Reflux Disease (NERD)
Status: COMPLETED
Conditions: Gastroesophageal Reflux|Heartburn
Interventions: DRUG: rabeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Preemptive TIPS for Gastric Variceal Bleeding in Patients With Cirrhosis
Status: NOT_YET_RECRUITING
Conditions: Portal Hypertension|Gastric Varices Bleeding|Portosystemic Shunt
Interventions: PROCEDURE: preemptive TIPS|PROCEDURE: standard second prophylaxis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Qigong Exercise Training After Thoracotomy
Status: COMPLETED
Conditions: Pain, Shoulder|Postoperative Pain|Joint Adhesion|Muscle Weakness|Respiratory Function Loss|Quality of Life
Interventions: OTHER: Qigong exercise training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: "Platelet Rich Plasma for the Management of Post-Viral Olfactory Dysfunction.
Status: ENROLLING_BY_INVITATION
Conditions: Olfactory Disorder|Olfaction Disorders
Interventions: OTHER: Platelet rich plasma|OTHER: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Medical Care, Education, Social Support, And Goal-setting to Empower Self-management for Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: OTHER: Diabetes MESSAGES Program|OTHER: Diabetes MESSAGES Program (second trial)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Stem Cell Therapy in Non-IschEmic Non-treatable Dilated CardiomyopathiEs II: a Pilot Study
Status: UNKNOWN
Conditions: Non-ischemic Dilated Cardiomyopathy
Interventions: BIOLOGICAL: Allogeneic adipose-derived stromal cells (CSCC_ASC)|OTHER: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Swiss Dermatology Network of Targeted Therapies (SDNTT)
Status: RECRUITING
Conditions: Psoriasis
Interventions: BIOLOGICAL: Adalimumab|BIOLOGICAL: Etanercept|BIOLOGICAL: Infliximab|BIOLOGICAL: Ustekinumab|DRUG: Cyclosporine A|DRUG: Fumaric acids|DRUG: Methotrexate|DRUG: Other anti-psoriatic systemic treatments
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: L-CsA in the Prevention of Bronchiolitis Obliterans Syndrome (BOS) in Lung Transplant (LT) Patients
Status: TERMINATED
Conditions: Bronchiolitis Obliterans
Interventions: DRUG: Cyclosporine Inhalation Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Use of Wearable Sensors for Early Detection and Tracking of Viral Respiratory Tract Infections
Status: COMPLETED
Conditions: Viral Respiratory Tract Infection|Influenza
Interventions: BIOLOGICAL: Administration of FluMist (Live Attenuated Influenza Vaccine)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Metronomic Capecitabine With or Without PD-1 Antibody as Adjuvant Therapy in High-risk Nasopharyngeal Carcinoma
Status: RECRUITING
Conditions: Nasopharyngeal Carcinoma
Interventions: DRUG: PD-1 antibody|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bronchodilator Effect of CHF1535 pMDI Versus Free Combination of Beclometasone Plus Formoterol pMDI in Asthmatic Children
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: beclomethasone+formoterol 50/6 (1 inhalation)|DRUG: CHF 1535 50/6 (2 inhalations)|DRUG: CHF 1535 50/6 (4 inhalations)|DRUG: Formoterol + Beclomethasone dipropionate|DRUG: Placebo (6 inhalations)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CAMELLIA Cohort: A Longitudinal Study to Understand Sexual Health and Prevention Among Women in Alabama
Status: ENROLLING_BY_INVITATION
Conditions: Hiv|Sexually Transmitted Diseases
Interventions: BEHAVIORAL: Camelia Cohort
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Trial of Pembrolizumab (MK-3475) in Participants With Blood Cancers (MK-3475-013/KEYNOTE-013)
Status: COMPLETED
Conditions: Myelodysplastic Syndrome|Multiple Myeloma|Hodgkin Lymphoma|Non-Hodgkin Lymphoma|Diffuse Large B-Cell Lymphoma|Follicular Lymphoma|Primary Mediastinal B-Cell Lymphoma
Interventions: BIOLOGICAL: Pembrolizumab|DRUG: Lenalidomide 20 mg|DRUG: Lenalidomide 25 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Macular Pigment and Visual Performance in Glaucoma Patients
Status: TERMINATED
Conditions: Glaucoma
Interventions: DRUG: Lutein, zeaxanthin and mesozeaxanthin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Single-Arm Comprehensive Ablative Bridging Irradiation I Prior to CD19 CAR-T In High-Risk R/R LBCL
Status: RECRUITING
Conditions: Large B-cell Lymphoma|Relapsed Non-Hodgkin Lymphoma
Interventions: RADIATION: Comprehensive Ablative Bridging Irradiation (CABI)|BIOLOGICAL: Chimeric Antigen Receptor T-Cell Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of the Axillary Lymphatic /Vein Reflux Ratio on Postoperative Upper Limb Edema and Dysfunction in Breast Cancer
Status: RECRUITING
Conditions: Breast Cancer Lymphedema
Interventions: PROCEDURE: Branches Sparing|PROCEDURE: None Branches Sparing
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Intravenous Compared With Intrahepatic Chemotherapy in Treating Patients With Colorectal Cancer Metastatic to the Liver
Status: UNKNOWN
Conditions: Colorectal Cancer|Metastatic Cancer
Interventions: DRUG: fluorouracil|DRUG: isolated perfusion|DRUG: leucovorin calcium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Comparative Efficacy of Dutasteride Plus Tamulosin With Lifestyle Advice Versus Watchful Waiting Plus Lifestyle Advice in the Management of Treatment naïve Men With Moderately Symptomatic Benign Prostatic Hyperplasia and Prostate Enlargement
Status: COMPLETED
Conditions: Prostatic Hyperplasia
Interventions: DRUG: Dutasteride plus tamsulosin|DRUG: tamsulosin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Examination of the Value of Shortwave Diathermy and Hydrotherapy for Patients With Osteoarthritis of Their Knees
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: OTHER: Continuous short wave diathermy (CSWD)|OTHER: Hydrotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Dexamethasone in Attenuation of Postinduction Hypotension in Geriatric Patients Undergoing General Anesthesia
Status: COMPLETED
Conditions: Hypotension
Interventions: DRUG: Dexamethasone|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: PAtient-centered mUltidiSciplinary Care for vEterans Undergoing Surgery (PAUSE)
Status: ENROLLING_BY_INVITATION
Conditions: Frailty
Interventions: OTHER: PAUSE Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Ectoin® Mouth Wash (EML03) in the Prevention and Treatment of Radiation-induced Oral Mucositis
Status: COMPLETED
Conditions: Oral Mucositis Due to Radiation
Interventions: DRUG: Ectoin Mouth Wash|DRUG: Supersaturated solution of calcium and phosphate ions
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Treatment of the Bilateral Severe Uveitis by IVT of Regulator T-cells: Study of Tolerance of Dose
Status: SUSPENDED
Conditions: Uveitis
Interventions: OTHER: intravitreous administration of regulator T-cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Using Behavioral Science to Reduce Inappropriate Antibiotic Use in Acute Care Settings
Status: COMPLETED
Conditions: Antimicrobial Stewardship|Acute Bronchitis|Upper Respiratory Infection
Interventions: BEHAVIORAL: Antibiotic Stewardship
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Use of Photobiomodulation in the Treatment of Oral Complaints of Long COVID-19.A Randomized Controlled Trial.
Status: COMPLETED
Conditions: Xerostomia|COVID-19|Long COVID|Persistent COVID-19
Interventions: COMBINATION_PRODUCT: Institutional standard treatment for xerostomia and Long Covid|RADIATION: Photobiomodulation Therapy|RADIATION: Placebo Photobiomodulation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intralesional Ranibizumab on Pterygium Vascularity, Size and Recurrence Rate: a Pilot Study
Status: COMPLETED
Conditions: Pterygium
Interventions: DRUG: ranibizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Omega-3 Fatty Acids(Omacor®) for the Treatment of Immunoglobulin A Nephropathy
Status: COMPLETED
Conditions: IgA Nephropathy
Interventions: DRUG: Omega-3 fatty acid ethylester90
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Getting Malaria "Off the Back" of Women and Children in Western Uganda
Status: COMPLETED
Conditions: Malaria
Interventions: OTHER: Permethrin-treated Lesu (baby wrap)|OTHER: Untreated Lesu (baby wrap)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: mTor-inhibitor (EVERolimus) Based Immunosuppressive Strategies for CNI Minimisation in OLD for Old Renal Transplantation
Status: COMPLETED
Conditions: Renal Transplant
Interventions: DRUG: Anti R-IL2 + Cyclosporine|DRUG: Thymoglobulin + Everolimus|DRUG: Anti R-IL2 + Cyclosporine then Everolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antenatal Educational Intervention for Improvement of Breastfeeding
Status: COMPLETED
Conditions: Breastfeeding
Interventions: BEHAVIORAL: individual lactation counseling and educational material|BEHAVIORAL: educational material alone|BEHAVIORAL: routine antenatal care without educational intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: ECT
Clinical trial: A Phase 2b Study of SPI-1005 to Prevent Acute Noise Induced Hearing Loss
Status: UNKNOWN
Conditions: Noise Induced Hearing Loss
Interventions: DRUG: SPI-1005 200mg|DRUG: SPI-1005 400mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Long-term Efficacy, Safety, and Tolerability Study of BOTOX® in Patients With Chronic Migraine
Status: COMPLETED
Conditions: Migraine Disorders
Interventions: BIOLOGICAL: onabotulinumtoxinA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Sotatercept in Newly Diagnosed Intermediate- and High-Risk PAH Participants (MK-7962-005/A011-13)
Status: RECRUITING
Conditions: Pulmonary Arterial Hypertension
Interventions: DRUG: Sotatercept|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Volume Mode Non-invasive Ventilation in Amyotrophic Lateral Sclerosis
Status: RECRUITING
Conditions: Amyotrophic Lateral Sclerosis|Respiratory Failure|Respiratory Insufficiency|Sleep-Disordered Breathing|Neuro-Degenerative Disease|Neuron Disease, Motor|Nervous System Diseases|Neuromuscular Diseases
Interventions: DEVICE: iVAPS-AE|DEVICE: ST-mode
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Conbercept Injection Through Different Routes for Neovascular Glaucoma
Status: COMPLETED
Conditions: Neovascular Glaucoma
Interventions: PROCEDURE: Intracameral injection|PROCEDURE: Intravitreal injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pembrolizumab Plus Chemotherapy in 1st Line Treatment of Pancreatic Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Pancreatic Cancer|Chemotherapy Effect
Interventions: DRUG: Gemcitabine|DRUG: Nab-paclitaxel|DRUG: Pembrolizumab|DRUG: Oxaliplatin|DRUG: Leucovorin|DRUG: Irinotecan|DRUG: 5FU
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Lidocaine and Tetracaine Cream for Facial Laser Aesthetics in Chinese Adults
Status: NOT_YET_RECRUITING
Conditions: Analgesia
Interventions: DRUG: Lidocaine tetracaine cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Human Umbilical Cord Mesenchymal Stem Cells (MSCs) Therapy in ARDS
Status: UNKNOWN
Conditions: Acute Respiratory Distress Syndrome
Interventions: BIOLOGICAL: umbilical cord derived mesenchymal stem cells (UCMSCs) suspension|BIOLOGICAL: normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bacteriophage Therapy TP-102 in Patients With Diabetic Foot Infection
Status: RECRUITING
Conditions: Diabetic Foot Infection
Interventions: BIOLOGICAL: TP-102|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Single Dose Comfort Comparison of Travatan Z in One Eye Versus Xalatan in the Opposite Eye in Patients With Primary Open-Angle Glaucoma or Ocular Hypertension
Status: COMPLETED
Conditions: Open-Angle Glaucoma|Ocular Hypertension
Interventions: DRUG: Travoprost ophthalmic solution 0.004% with SofZia® preservative system (TRAVATAN Z®)|DRUG: Latanoprost ophthalmic solution 0.005% (XALATAN®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Dexmedetomidine (DEX) for Sedation of Subjects ≥1 Month to <17 Years Undergoing MRI Scans
Status: COMPLETED
Conditions: MRI Sedation
Interventions: DRUG: dexmedetomidine|DRUG: propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Acceptability and Tolerance of a Ready-to-use Protein Substitute in Tablet Form for the Dietary Management of Phenylketonuria
Status: COMPLETED
Conditions: Phenylketonurias|Hyperphenylalaninaemia|Tetrahydrobiopterin Deficiency
Interventions: DIETARY_SUPPLEMENT: Phenylalanine-free protein substitute in tablet form (XPhe minis)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Direct Oral Anticoagulants (DOACs) Versus LMWH +/- Warfarin for VTE in Cancer
Status: COMPLETED
Conditions: Cancer|Venous Thromboembolism|Deep Vein Thrombosis (DVT)|Pulmonary Embolism (PE)|Blood Clot
Interventions: DRUG: Rivaroxaban|DRUG: Apixaban|DRUG: Edoxaban|DRUG: Dabigatran|DRUG: Warfarin|DRUG: Dalteparin|DRUG: Enoxaparin|DRUG: Fondaparinux
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of a Monovalent Conjugated Vaccine Against Haemophilus Influenzae Type b
Status: COMPLETED
Conditions: Haemophilus Influenzae Type b
Interventions: BIOLOGICAL: Haemophilus influenzae type b vaccine|BIOLOGICAL: Commercial Haemophilus influenzae type b vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Phase III Study of Ceralasertib Plus Durvalumab Versus Docetaxel in Patients With Non Small Cell Lung Cancer (NSCLC) Whose Disease Progressed On or After Prior Anti PD (L)1 Therapy And Platinum Based Chemotherapy
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced or Metastatic Non-Small Cell Lung Cancer
Interventions: DRUG: Ceralasertib|DRUG: Durvalumab|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pain Control After Lumbar Spine Fusion
Status: ENROLLING_BY_INVITATION
Conditions: Spine Fusion|NSAID (Non-Steroidal Anti-Inflammatory Drug)|Postoperative Pain
Interventions: DRUG: Naproxen 500 Mg|DRUG: Ketorolac|DRUG: OxyCODONE 5 mg Oral Tablet|DRUG: Metaxalone 800 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Examining the Effects of Diet on Health With an Online Program
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: BEHAVIORAL: Behavioral: Low Carbohydrate, Ketogenic Diet|BEHAVIORAL: American Diabetes Association Diet|BEHAVIORAL: Mindfulness and Positive Affect Skills
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study to Assess the Effect on Pharmacokinetics of Dosing Mirabegron (YM178) and Solifenacin Simultaneously
Status: COMPLETED
Conditions: Healthy Volunteers|Pharmacokinetics of Mirabegron
Interventions: DRUG: solifenacin succinate|DRUG: mirabegron
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study Testing The Safety and Efficacy of Adjuvant Temozolomide Plus TTFields (Optune®) Plus Pembrolizumab in Patients With Newly Diagnosed Glioblastoma (2-THE-TOP)
Status: ACTIVE_NOT_RECRUITING
Conditions: Glioblastoma|Glioblastoma, WHO Grade IV
Interventions: DRUG: Temozolomide (TMZ)|DEVICE: Optune System|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Comparison of xiEnce and visioN Coronary Stents in the sAme muLtivessel Patient With Chronic kiDnEy diSease
Status: COMPLETED
Conditions: Chronic Kidney Disease|Multivessel Coronary Artery Disease
Interventions: DEVICE: Coronary stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Misago® RX Self-expanding Peripheral Stent for Common and/or External Iliac Artery
Status: ACTIVE_NOT_RECRUITING
Conditions: Iliac Artery Stenosis
Interventions: DEVICE: Misago® RX Self-expanding Peripheral Stent
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Allogeneic Donor Lymphocyte Infusions Combined With Blinatumomab
Status: WITHDRAWN
Conditions: B Cell Precursor Acute Lymphoblastic Leukemia With Mixed Chimerism or Minimal Residual Disease After Allogeneic Stem Cell Transplantation|B-Cell Acute Lymphoblastic Leukemia|Acute Lymphoblastic Leukemia|Acute Lymphoblastic Leukemia in Remission|Acute Lymphoblastic Leukemia, Adult
Interventions: DRUG: Blinatumomab in combination with donor lymphocyte infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing the Pharmacodynamics and Pharmacokinetics of Explorative Formulation of Insulin Degludec With Insulin Glargine in Subjects With Type 1 and Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 1|Diabetes Mellitus, Type 2
Interventions: DRUG: insulin degludec|DRUG: insulin glargine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Nivolumab Alone or in Combination With Ipilimumab in Treating Patients With Advanced Uterine Leiomyosarcoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Leiomyosarcoma|Unresectable Leiomyosarcoma|Uterine Corpus Leiomyosarcoma
Interventions: BIOLOGICAL: Ipilimumab|OTHER: Laboratory Biomarker Analysis|BIOLOGICAL: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Research Study Looking at a New Study Medicine (NNC0194-0499) for Weight Control in People With Overweight or Obesity
Status: COMPLETED
Conditions: Metabolism and Nutrition Disorder|Obesity
Interventions: DRUG: NNC0194-0499|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ketamine on Acute Pain in Females and Males
Status: COMPLETED
Conditions: Mouth and Tooth Diseases|Tooth, Impacted
Interventions: DRUG: Placebo males|DRUG: Ketamine 0,1 mg/kg males|DRUG: Ketamine 0,3 mg/kg males|DRUG: Ketamine 0,5 mg/kg males|DRUG: Placebo females|DRUG: Ketamine 0,1 mg/kg females|DRUG: Ketamine 0,3 mg/kg females|DRUG: Ketamine 0,5 mg/kg females
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Exercise Substrate Utilisation and Endurance Performance Following Short-term Manipulation of Dietary Fat Intake
Status: UNKNOWN
Conditions: Dietary Modification
Interventions: DIETARY_SUPPLEMENT: High Fat|DIETARY_SUPPLEMENT: Normal|DIETARY_SUPPLEMENT: Normal + Extra Fat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Treatment of Chronic Granulomatous Disease With Allogeneic Stem Cell Transplantation Versus Standard of Care
Status: COMPLETED
Conditions: Chronic Granulomatous Disease
Interventions: DRUG: T-Cell Depleted & CD34+Select/w/StemCell Enriched Product
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Study of PF-05208756, Moroctocog Alfa (AF-CC), Xyntha For Male Chinese Subjects With Hemophilia A
Status: COMPLETED
Conditions: Hemophilia A
Interventions: DRUG: Intravenous infusions of Xyntha
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Immediate Effect of Subliminal Priming With Subliminal Reward Stimuli on Standing Balance in Healthy Young Adults
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: Subliminal priming with subliminal reward stimuli|OTHER: Subliminal priming with supraliminal reward stimuli
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Controling Intestinal Colonization With Extended Spectrum ß-Lactamase Producing Enterobacteriaceae ESBL-E
Status: TERMINATED
Conditions: Cancer
Interventions: DRUG: ESBL eradication regimen|DRUG: Placebo ESBL eradication
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Improving ADHD Teen Driving
Status: COMPLETED
Conditions: Attention Deficit Disorder|Attention Deficit Disorder With Hyperactivity
Interventions: BEHAVIORAL: FOCAL+|OTHER: Rules of The road
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Retinal Neuro-vascular Coupling in Patients With Non-arteritic Anterior Ischemic Optic Neuropathy
Status: COMPLETED
Conditions: Anterior Ischemic Optic Neuropathy
Interventions: DEVICE: Dynamic Vessel Analyzer (DVA)|DEVICE: Fourier Domain Doppler Optical Coherence Tomography (FDOCT)|DEVICE: Optical coherence tomography (OCT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Use of Wearable Tech to Increase Physical Activity in Inpatient Rehabilitation for Patients With Chronic Pain
Status: COMPLETED
Conditions: Chronic Pain|Musculoskeletal Pain
Interventions: DEVICE: Wearable tech with feedback|DEVICE: Wearable tech without feedback|BEHAVIORAL: Rehabilitation program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Technology-Enhanced Quitline Services to Prevent Smoking Relapse
Status: COMPLETED
Conditions: Smoking Cessation
Interventions: BEHAVIORAL: Quitline Service + 10 automated monitoring calls|BEHAVIORAL: Quitline service + 20 automated monitoring calls
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Fixed Dose Combination of COdeine + DIpyrone to Mitigate Moderate to Intense Pain Post-impacted Third Lower Molar Extraction
Status: RECRUITING
Conditions: Pain
Interventions: DRUG: FDC of codeine 30 mg/dipyrone 500 mg|DRUG: Tylex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Obstructive Sleep Apnea in Children: An Opportunity for Cardiovascular Risk Modification
Status: COMPLETED
Conditions: Obesity|Obstructive Sleep Apnea|Sleep Disorders|Cardiovascular Disease
Interventions: DEVICE: cPAP|DEVICE: cPAP, Continuation|DEVICE: cPAP, Discontinuation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: The Efficacy and Safety of Fotona Smooth® Device for the Treatment of Stress Urinary Incontinence
Status: UNKNOWN
Conditions: Stress Urinary Incontinence
Interventions: DEVICE: Fotona Dynamis Er:YAG Laser System|DEVICE: Fotona Dynamis Er:YAG Laser System with sham handpience
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Tislelizumab Combined With S-1 Plus Oxaliplatin as a Neoadjuvant Treatment in Patients With GC/GEJC
Status: UNKNOWN
Conditions: Advanced Gastric Cancer|Advanced Gastroesophageal Junction Adenocarcinoma
Interventions: DRUG: PD-1 inhibitor(Tislelizumab) ,SOX(S-1+ Oxaliplatin)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: International Prospective Registry on Local Treatment Approaches in MLS
Status: RECRUITING
Conditions: Myxoid Liposarcoma
Interventions: PROCEDURE: Surgery|RADIATION: Preoperative RT 36Gy|RADIATION: Preoperative RT 50Gy|RADIATION: Postoperative RT 50-66Gy|RADIATION: RT 36Gy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Fitness Integrative Training for Pediatric Rheumatology Disorders
Status: RECRUITING
Conditions: Juvenile Idiopathic Arthritis|Systemic Lupus Erythematosus of Childhood|Joint Hypermobility|Juvenile Dermatomyositis
Interventions: BEHAVIORAL: FIT Teens
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: In Vivo Inhibition Profile of CYP2C9 by Pineapple Juice
Status: UNKNOWN
Conditions: Healthy Volunteers
Interventions: DIETARY_SUPPLEMENT: pineapple juice (Carrefour n°1) 500 ml/day 5 days
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Decreasing Parental Stress of Caregivers of Infants With Infantile Spasms by Using Telemedicine Technology
Status: UNKNOWN
Conditions: Infantile Spasms, Non-Intractable
Interventions: OTHER: Remote monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Clinical Efficacy Evaluation of Electroacupuncture as Adjuvant Therapy for Female Patients With Overactive Bladder
Status: RECRUITING
Conditions: Overactive Bladder
Interventions: DEVICE: electroacupuncture|DEVICE: sham acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Sleep-directed Hypnosis As A Complement To Cognitive Processing Therapy (CPT) In Treating Posttraumatic Stress Disorder (PTSD)
Status: UNKNOWN
Conditions: Posttraumatic Stress Disorder
Interventions: BEHAVIORAL: Cognitive Processing Therapy|BEHAVIORAL: Hypnosis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Efficacy of SeS2 Shampoo on Subjects Having Dandruff
Status: UNKNOWN
Conditions: Dandruff
Interventions: OTHER: dermatological product
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Axitinib (AG 013736) As Second Line Therapy For Metastatic Renal Cell Cancer
Status: COMPLETED
Conditions: Kidney Neoplasms
Interventions: DRUG: Axitinib (AG-013736)|DRUG: Sorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HepeX-B in Post Hepatic Allografts for Treatment of End Stage Liver Disease Due to Hepatitis B Infection
Status: TERMINATED
Conditions: Hepatitis B|Liver Transplantation
Interventions: DRUG: HepeX-B|DRUG: Hepatitis B Immune Globulin (HBIg)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION