pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Comparison of TIcagrelor and Clopidogrel in Patients With Coronary Artery diseaSe and Type 2 Diabetes Mellitus (TICS-DM)
Status: UNKNOWN
Conditions: Coronary Artery Disease|Diabetes Mellitus. Type 2
Interventions: DRUG: Ticagrelor|DRUG: Clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Insulin Aspart vs. Regular Human Insulin in Gestational Diabetes
Status: COMPLETED
Conditions: Diabetes|Gestational Diabetes
Interventions: DRUG: human insulin|DRUG: insulin NPH|DRUG: insulin aspart
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Melanoma Vaccine Against Neoantigen and Shared Antigens by CD40 Activation and TLR Agonists In Patients With Melanoma (Including Ocular Melanoma)
Status: COMPLETED
Conditions: Melanoma|Ocular Melanoma|Uveal Melanoma
Interventions: DRUG: 6MHP|DRUG: NeoAg-mBRAF|DRUG: PolyICLC|DRUG: CDX-1140
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Different Schemes of Magnesium Sulfate for Preeclampsia
Status: TERMINATED
Conditions: Preeclampsia
Interventions: DRUG: Magnesium sulfate 50% - 1g/h|DRUG: Magnesium sulfate 50% - 2g/h
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Learn About the Study Medicine Called PF-07799544 in People With Advanced Solid Tumors
Status: RECRUITING
Conditions: Melanoma|Glioma|Thyroid Cancer|Non-Small Cell Lung Cancer|Malignant Neoplasms|Brain Neoplasms|Colorectal Cancer
Interventions: DRUG: PF-07799544|DRUG: PF-07799933|DRUG: encorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Virtual Dental Office Experience for Children With Autism Spectrum Disorder
Status: ENROLLING_BY_INVITATION
Conditions: Autism Spectrum Disorder
Interventions: DEVICE: Control Condition (Social Story)|DEVICE: Experimental Condition (360° Video)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: OTHER
Clinical trial: A Study of Azelaic Acid (AzA) 15% Gel in the Treatment of Seborrheic Dermatitis of the Face
Status: COMPLETED
Conditions: Seborrheic Dermatitis on the Face
Interventions: DRUG: Azelaic Acid 15% Gel|DRUG: Inactive 15% gel base
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to testABI-009 in Patients With Metastatic, Unresectable, Low or Intermediate Grade Neuroendocrine Tumors of the Lung or Gastroenteropancreatic System
Status: TERMINATED
Conditions: Neuroendocrine Tumors
Interventions: DRUG: ABI-009
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multiple Dose Study Evaluating the Safety and Tolerability of NSA-789
Status: COMPLETED
Conditions: Alzheimer Disease|Healthy Subjects
Interventions: DRUG: NSA-789|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of AdCh63 ME-TRAP and MVA ME-TRAP Vaccines in Malaria Endemic Areas
Status: COMPLETED
Conditions: Malaria
Interventions: BIOLOGICAL: AdCh63 ME-TRAP followed by MVA ME-TRAP|BIOLOGICAL: AdCh63 ME-TRAP followed by MVA ME-TRAP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Safety, Pharmacokinetics, and Pharmacodynamics Study of ABX464 in HIV-1 Seronegative and Seropositive Adults
Status: COMPLETED
Conditions: HIV Infections|Health Volunteers
Interventions: DRUG: ABX464 150mg|DRUG: ABX464 50mg|DRUG: ABX464 50mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of AK104 in Combination With Chiauranib in Patients With Extensive Stage Small Cell Lung Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: SCLC,Extensive Stage
Interventions: DRUG: AK104 IV infusion；Chiauranib oral
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Daclatasvir, Asunaprevir Plus Ribavirin for HCV Genotype 1b Without NS5A RAV
Status: COMPLETED
Conditions: Hepatitis C
Interventions: DRUG: daclatasvir|DRUG: asunaprevir|DRUG: Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Doravirine Concentrations and Antiviral Activity in Genital Fluids in HIV-1 Infected Individuals
Status: COMPLETED
Conditions: HIV-1-infection
Interventions: DRUG: Doravirine|DRUG: Descovy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Interventions With a Diet and Exercise on the Cardio-metabolic Status in Multi-risk Population
Status: ENROLLING_BY_INVITATION
Conditions: Cardiovascular Diseases|Metabolic Syndrome x|Mediterranean Diet
Interventions: DIETARY_SUPPLEMENT: Mediterranean diet and exercise plan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: µMRI of Therapeutic Intervention in Postmenopausal Osteoporosis
Status: COMPLETED
Conditions: Osteoporosis, Osteopenia
Interventions: OTHER: Virtual Bone Biopsy|DRUG: Teriparatide|DRUG: Zoledronic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Injection Site Pain Comparison of Excipient Solutions
Status: COMPLETED
Conditions: Obesity
Interventions: OTHER: Trial product 1|OTHER: Trial product 2|OTHER: Trial product 3|OTHER: Trial product 4|OTHER: Trial product 5|OTHER: Trial product 6|OTHER: Trial product 7|OTHER: Trial product 8|OTHER: Trial product 9|OTHER: Trial product 10|OTHER: Trial product 10|OTHER: Trial product 12
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Endovascular Stenting of Medically Refractory ICASD (Clinical and Sonographic Study)
Status: COMPLETED
Conditions: Stroke, Ischemic
Interventions: DEVICE: Intracranial Stenting by Intracranial Stent Device|DRUG: Optimum medical treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pfizer/IVGTT/Ziprasidone/Olanzapine
Status: COMPLETED
Conditions: Schizophrenia|Type 2 Diabetes Mellitus
Interventions: DRUG: Ziprasidone, Olanzapine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multi-Centre Clinical Trial to Evaluate a Left-Right Design in Adults With Mild to Moderate Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: pimecrolimus 10 mg/g cream|DRUG: Vehicle cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Molecular Mechanisms of Dutasteride and Dietary Interventions to Prevent Prostate Cancer and Reduce Its Progression
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostatic Neoplasms|Low Grade Prostate Cancer
Interventions: OTHER: Dietary intervention first|DRUG: Drug (Dutasteride) intervention first
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Open Label, Dose Escalation Trial of Oral Eg5 Kinesin-spindle Inhibitor 4SC-205 in Patients With Advanced Malignancies
Status: COMPLETED
Conditions: Advanced and Incurable Solid Tumors|Malignant Lymphomas
Interventions: DRUG: 4SC-205
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Methodology Study to Evaluate a Sitting Knee Measuring Device in Assessing Growth in Indian Children.
Status: COMPLETED
Conditions: Nutritional Status
Interventions: DIETARY_SUPPLEMENT: Nutritional supplement with micronutrient|DIETARY_SUPPLEMENT: Nutritional supplement without micronutrient
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: SAMe in Prevention of Oxaliplatin-associated Liver Injury
Status: NOT_YET_RECRUITING
Conditions: Colorectal Cancer|Liver Metastases|Liver Metastasis Colon Cancer|Liver Injury|Sinusoidal Obstruction Syndrome|5-Fluorouracil Toxicity|Liver Toxicity, Chemically-Induced
Interventions: RADIATION: Standard of care oxaliplatin-based chemotherapy|DIETARY_SUPPLEMENT: S-adenosylmethionine (SAMe) supplement|PROCEDURE: Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Evaluate the Whitening Effect of Mineral Sunscreens in Multi-Cultural Skin Tones
Status: COMPLETED
Conditions: Sunscreen
Interventions: OTHER: Sunscreen A|OTHER: Sunscreen B|OTHER: Sunscreen C|OTHER: Sunscreen D|OTHER: Sunscreen E|OTHER: Sunscreen F
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Immediate Mobilization Versus 2 Weeks Cast Immobilization After Distal Radius Fracture Treated With Volar Locking Plate
Status: RECRUITING
Conditions: Distal Radius Fracture
Interventions: OTHER: Cast treatment|OTHER: Immediate mobilization|PROCEDURE: Volar plating
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Efficacy and Tolerability Study of TEGAFOX Sequential S-1 in the Treatment of Adjuvant Chemotherapy for Gastric Cancer
Status: UNKNOWN
Conditions: Gastric Cancer
Interventions: DRUG: SOX Sequential S-1|DRUG: SOX|DRUG: TEGAFOX Sequential S-1.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tailored Web and Peer Email Cessation Counseling for College Smokers
Status: COMPLETED
Conditions: Cigarette Smoking
Interventions: BEHAVIORAL: Tailored Web|BEHAVIORAL: Peer Coaching|OTHER: Untailored Web
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Phototoxicity Potential of 6% Bemotrizinol
Status: COMPLETED
Conditions: Phototoxic Response
Interventions: DRUG: Sunscreen oil with 6% Bemotrizinol|OTHER: Sunscreen oil vehicle|DRUG: Dispersion of 6% BEMT in petrolatum|OTHER: Petrolatum vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Aromatase Inhibitor and Durvalumab in Postmenopausal Breast Cancer
Status: TERMINATED
Conditions: Breast Cancer|Hormone Receptor Positive Tumor
Interventions: DRUG: Durvalumab|DRUG: Anastrozole 1mg|DRUG: Letrozole 2.5mg|DRUG: Exemestane 25 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Metabolic Study of Highly Active Antiretroviral Therapy (HAART) in Malnourished Children With HIV
Status: COMPLETED
Conditions: Kwashiorkor|Marasmus|Severe Acute Malnutrition|HIV
Interventions: DRUG: zidovudine, lamivudine, nevirapine
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Colloidal Silver, Treatment of COVID-19
Status: UNKNOWN
Conditions: SARS (Severe Acute Respiratory Syndrome)
Interventions: DRUG: Colloidal Silver|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: CM-101 in PSC Patients -The SPRING Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Primary Sclerosing Cholangitis
Interventions: BIOLOGICAL: Anti-human CCL24 monoclonal antibody (CM-101)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prevalence and Natural History of Functional Gastrointestinal Disorders Among At-risk Infants.
Status: RECRUITING
Conditions: Functional Gastrointestinal Disorders|Gastroesophageal Reflux|Constipation - Functional|Diarrhea|Dyschezia|Colic, Infantile|Vomiting; Cyclical
Interventions: OTHER: Questionnaire, clinical examination
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Fibrinogen Concentrate In Children After Cardiac Surgery
Status: COMPLETED
Conditions: Cardiac Surgical Procedures|Blood Coagulation Disorders|Fibrinogen|Cryoprecipitate
Interventions: DRUG: Fibrinogen concentrate|DRUG: Cryoprecipitate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Sphincter Preservation Surgery and Abdominoperineal Resection (APR): Prospective Clinical Trial
Status: UNKNOWN
Conditions: Rectal Cancer
Interventions: PROCEDURE: Abdominoperineal resection|PROCEDURE: Sphincter preservation surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Desensitizing Effect and Tooth Color Change After Using Giomer-based Varnish Versus Bioactive Glass Air Polishing in Treating Cervical Hypersensitive Lesions
Status: NOT_YET_RECRUITING
Conditions: Dentin Hypersensitivity, Non-carious Cervical Lesions, Bioactive Glass Air Polishing, S-PRG
Interventions: OTHER: Giomer varnish containing surface pre-reacted glass fillers
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Plasma Concentration of YM150 After Repeated Administration to Elderly Subjects
Status: COMPLETED
Conditions: Healthy Elderly Subject|Pharmacokinetic of YM150
Interventions: DRUG: YM150|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Pediatric and Adolescent Patellar Instability
Status: ENROLLING_BY_INVITATION
Conditions: Patellar Instability
Interventions: PROCEDURE: Medial patellofemoral ligament reconstruction surgery|OTHER: Physical therapy and rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Preliminary Efficacy of Engineered Red Blood Cell in Patients With Advanced Malignancies
Status: RECRUITING
Conditions: Cancer|Solid Tumor|Hematologic Malignancy
Interventions: DRUG: engineered red blood cell
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase Ib Trial of the KRASG12C Inhibitor Adagrasib (MRTX849) in KRAS G12C Mutant Metastatic Pancreatic Cancer Patients
Status: RECRUITING
Conditions: Metastatic Pancreatic Cancer
Interventions: DRUG: MRTX849
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cellular Immune Responses in Typhoid Fever Patients and Vaccinees
Status: UNKNOWN
Conditions: Typhoid Fever Patients and Healthy Volunteers to Receive Typbar-TCV Vaccine
Interventions: BIOLOGICAL: Typbar-TCV vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Use of New Supraglottic Airway Devices in Severely Obese Patients: A Feasibility Study
Status: WITHDRAWN
Conditions: Obesity
Interventions: DEVICE: IGEL|DEVICE: King airway
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Nicotine Delivery Rate and Its Abuse Potential: Impact of Menthol
Status: COMPLETED
Conditions: Nicotine Dependence
Interventions: DRUG: Nicotine saline infusion 0.00mcg/kg/s|DRUG: Nicotine infusion 0.24mcg/kg/s|DRUG: Nicotine infusion 0.096mcg/kg/s|DRUG: Nicotine infusion 0.048 mcg/kg/s|DRUG: Nicotine infusion 0.024mcg/kg/s
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study About the Effect of Preventive Adjacent Level Cement Augmentation After Osteoporotic Vertebral Compression Fractures
Status: TERMINATED
Conditions: Osteoporosis|Vertebral Fracture
Interventions: PROCEDURE: Augmentation vertebroplasty|PROCEDURE: Augmentation and prophylactic vertebroplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Multicenter Study of Oral Versus Intravenous Hydration in AIDS Patients With CMV Retinitis Treated With Foscavir (Foscarnet Sodium)
Status: COMPLETED
Conditions: Cytomegalovirus Retinitis|HIV Infections
Interventions: DRUG: Foscarnet sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy and Bevacizumab With the NovoTTF-100L(P) System in Treating Participants With Advanced, Recurrent, or Refractory Hepatic Metastatic Cancer
Status: RECRUITING
Conditions: Advanced Malignant Neoplasm|Colorectal Carcinoma Metastatic in the Liver|Metastatic Malignant Neoplasm in the Liver|Refractory Malignant Neoplasm
Interventions: BIOLOGICAL: Bevacizumab|DRUG: Fluorouracil|DRUG: Leucovorin|DRUG: Oxaliplatin|DRUG: Pegylated Liposomal Doxorubicin Hydrochloride|DRUG: Temsirolimus|PROCEDURE: Tumor Treating Fields Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of "Sputnik Lite" for the Prevention of COVID-19 With Altered Antigenic Composition.
Status: NOT_YET_RECRUITING
Conditions: COVID-19
Interventions: BIOLOGICAL: "Sputnik Lite" vaccine for the prevention of COVID-19 with altered antigenic composition
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Clinical Effectiveness of the ReHand App in Hand Rehabilitation After Stroke
Status: COMPLETED
Conditions: Stroke|Mobility Limitation|Neurologic Disorder|Motor Disorders|Hand Presentation
Interventions: OTHER: Tablet Application|OTHER: Conventional Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Perioperative iv Dexmedetomidine vs. Lidocaine on Postoperative Pain, Analgesic Consumption and Recovery After Abdominal Gynaecological Surgery
Status: UNKNOWN
Conditions: Hysterectomy|Myomectomy
Interventions: DRUG: Lidocaine Iv|DRUG: Dexmedetomidine|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Immunogenicity and Safety Study of GSK Biologicals' Human Papillomavirus 580299 Vaccine in Healthy Female Subjects
Status: COMPLETED
Conditions: Infections, Papillomavirus
Interventions: BIOLOGICAL: CervarixTM|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of Nebivolol Versus Metoprolol in Hypertensive Subject Taking Amlodipine
Status: COMPLETED
Conditions: JNC 7 Stage 1 or 2 Hypertension
Interventions: DRUG: Nebivolol I|DRUG: Nebivolol II|OTHER: Baseline Washout Phase
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Lidocaine: Effect of Lidocaine in Chronic Cough
Status: COMPLETED
Conditions: Chronic Cough
Interventions: DRUG: 10 % Lidocaine|DRUG: 10 % Lidocaine|DRUG: 0.9% saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Provider Commitments to Choose Wisely
Status: COMPLETED
Conditions: Health Services Misuse|Physician's Practice Patterns|Guideline Adherence|Unnecessary Procedures|Health Care Costs
Interventions: BEHAVIORAL: Commitment Invitation for Clinicians (Clinician Intervention)|OTHER: Health Education Materials to Patients (Patient Intervention)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Maimonides Minocycline in Stroke Study
Status: RECRUITING
Conditions: Stroke, Acute|Ischemic Stroke|Hemorrhagic Stroke|Mortality|Morbidity
Interventions: DRUG: Minocycline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Growth Hormone in Poor Responders to IVF Trial
Status: TERMINATED
Conditions: Infertility
Interventions: DRUG: Saizen (Human Growth Hormone)|DRUG: Saizen (Human Growth Hormone)|DRUG: No Saizen Control (Standard IVF Protocol)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparison of 3D and 2D Telemedicine During Covid 19
Status: UNKNOWN
Conditions: Telehealth
Interventions: OTHER: 3D Telemedicine|OTHER: 2D Telemedicine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Targeting Microenvironment and Cellular Immunity in Sarcomas Weekly Trabectedin Combined With Metronomic Cyclophosphamide
Status: COMPLETED
Conditions: Soft-tissue Sarcomas
Interventions: DRUG: Phase 1: Trabectedin|DRUG: Phase 2: Trabectedin|DRUG: Phase 1: Cyclophosphamide|DRUG: Phase 2: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sunitinib as Second-Line Therapy in Treating Patients With Locally Advanced or Metastatic Transitional Cell Cancer
Status: COMPLETED
Conditions: Bladder Cancer|Transitional Cell Cancer of the Renal Pelvis and Ureter
Interventions: DRUG: sunitinib malate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MEDI2228 in Subjects With Relapsed/Refractory Multiple Myeloma
Status: COMPLETED
Conditions: Relapsed/Refractory Multiple Myeloma
Interventions: BIOLOGICAL: Dose Escalation, MEDI2228, ADC (antibody drug conjugate)|BIOLOGICAL: Dose Expansion, MEDI2228, ADC (antibody drug conjugate)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Omalizumab (Xolair®) to Treat Chronic Urticaria
Status: COMPLETED
Conditions: Chronic Urticaria
Interventions: BIOLOGICAL: Omalizumab|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability of a Single Intra-anal Dose of NRL001 in Healthy Volunteers
Status: COMPLETED
Conditions: Fecal Incontinence
Interventions: DRUG: Placebo control|DRUG: NRL001 cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prophylactic Tamsulosin in Prevention of Post-operative Urinary Retention in Men After Transanal Endoscopic Microsurgery
Status: UNKNOWN
Conditions: Urinary Retention
Interventions: DRUG: Tamsulosin Hydrochloride 0.4 MG|DRUG: Placebo oral capsule|DEVICE: Foley catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Subcutaneous Immunoglobulin for Myasthenia Gravis
Status: RECRUITING
Conditions: Myasthenia Gravis
Interventions: DRUG: subcutaneous immunoglobulin (SCIG)|DRUG: intravenous immunoglobulin + subcutaneous immunoglobulin (SCIG)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Protocol Calcineurin Inhibitor (CNI) Weaning
Status: TERMINATED
Conditions: Function of Renal Transplant
Interventions: DRUG: Tacrolimus|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Long-term Treatment Study of MRA for Polyarticular Juvenile Idiopathic Arthritis (pJIA)
Status: COMPLETED
Conditions: Polyarticular Juvenile Idiopathic Arthritis
Interventions: DRUG: MRA(Tocilizumab)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ph2a Study to Evaluate IW-3718 in Patients With Gastroesophageal Reflux Not Completely Responsive to Proton Pump Inhibitors
Status: COMPLETED
Conditions: Gastroesophageal Reflux
Interventions: DRUG: IW-3718|DRUG: Matching Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of CAEL-101 in Patients With Mayo Stage IIIb AL Amyloidosis
Status: ACTIVE_NOT_RECRUITING
Conditions: AL Amyloidosis
Interventions: DRUG: CAEL-101|OTHER: Placebo|DRUG: cyclophosphamide, bortezomib, and Dexamethasone (CyBorD) regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Basel Enteral High Protein Study
Status: TERMINATED
Conditions: High Enteral Protein Nutrition|Muscle Breakdown|Autophagy
Interventions: OTHER: Standardized high protein enteral nutrition|OTHER: Standardized normal protein enteral nutrition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Optimizing Mental Health Management With AI-Guided (GenAIS TM) Dietary Supplementation
Status: COMPLETED
Conditions: Mental Disorder
Interventions: OTHER: Standard therapy group|OTHER: AI-Guided group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: OPtimising thERapy to Prevent Avoidable Hospital Admissions in the Multimorbid Older People
Status: COMPLETED
Conditions: 3 or More Chronic Conditions for 6 Months or Longer|5 or More Regular Drugs
Interventions: OTHER: STRIP intervention|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: rTMS in Aphasic Patients With Neuroimage Assessments
Status: UNKNOWN
Conditions: Stroke|Aphasia
Interventions: DEVICE: repetitive transcranial magnetic stimulation (rTMS)|DEVICE: Sham stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combining Antidepressant Medication and Psychotherapy for Insomnia to Improve Depression Outcome
Status: COMPLETED
Conditions: Major Depressive Disorder|Insomnia
Interventions: DRUG: Escitalopram|BEHAVIORAL: CBTI|BEHAVIORAL: CTRL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vyvanse in Children Aged 6 to 12 Years
Status: RECRUITING
Conditions: Obesity, Childhood
Interventions: DRUG: Lisdexamfetamine Dimesylate|BEHAVIORAL: Lifestyle therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cayenne Pepper Cataplasm - Safety Study
Status: COMPLETED
Conditions: Low Back Pain
Interventions: DRUG: Cayenne Pepper topical|DEVICE: Electrical stimulation|PROCEDURE: Massage
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Development of an Optimal Approach to Return of Results for Next-generation Sequencing for Prenatal Diagnosis
Status: WITHDRAWN
Conditions: Major Fetal Anomaly
Interventions: GENETIC: Whole Genome Sequencing|PROCEDURE: Amniocentesis|OTHER: Psychosocial assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Carpentier-Edwards PERIMOUNT Magna Ease Pericardial Bioprosthesis, Model 3300TFX
Status: COMPLETED
Conditions: Coronary Artery Disease|Aortic Valve Disorder|Heart Failure|Aortic Valve Stenosis|Aortic Valve Insufficiency
Interventions: DEVICE: Implantation of CEP Magna Ease Model 3300TFX
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Dose Escalation Study in Solid Tumors and a Dose Expansion Study of PRN1371 in Adult Patients With Metastatic Urothelial Carcinoma
Status: TERMINATED
Conditions: Solid Tumors|Metastatic Urothelial Carcinoma & Renal Pelvis & Ureter
Interventions: DRUG: PRN1371
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized Control Trial for Patient Reported Outcomes and Safety in Outpatient Thyroid Lobectomy
Status: NOT_YET_RECRUITING
Conditions: Thyroid Lobectomy
Interventions: BEHAVIORAL: Pre-Surgery Survey|BEHAVIORAL: Post-Surgery Surveys
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Impact of Integrative Medicine on Patient-Reported Outcomes in Management of Chronic Pelvic Pain
Status: COMPLETED
Conditions: Chronic Female Pelvic Pain Syndrome (Disorder)
Interventions: BEHAVIORAL: Mindfulness counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Influence of Soy Isoflavnoids on the Hypocholesterolemic Effects of Soy
Status: COMPLETED
Conditions: Hyperlipidemia|Cardiovascular Diseases
Interventions: PROCEDURE: dairy food control diet and high- and low- isoflavone soyfood diets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Rifabutin Versus Rifampicin for Treatment of Staphylococcal PJI Treated With DAIR
Status: RECRUITING
Conditions: Prosthetic Infection
Interventions: DRUG: Rifabutin|DRUG: Rifampicin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Compare the Efficacy Between 3 Fetal Monitoring Methods (EUM)
Status: UNKNOWN
Conditions: Fetal Heartbeat Tracings
Interventions: DEVICE: Scalp electrode,|DEVICE: Fetal doppler|DEVICE: EUM
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Phase III Study of Compound Formula Realgar-Indigo Naturalis Plus Imatinib Versus Placebo Plus Imatinib in Adult CML-CP Patients With Ph+
Status: SUSPENDED
Conditions: Chronic Myelogenous Leukemia
Interventions: DRUG: Compound realgar natural indigo Tablet|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of IPX054, IR Carbidopa-Levodopa, and CR Carbidopa-Levodopa in Subjects With Parkinson's Disease
Status: COMPLETED
Conditions: Idiopathic Parkinson's Disease
Interventions: DRUG: IPX054 200 mg|DRUG: IPX054 250 mg|DRUG: CD-LD IR|DRUG: CD-LD CR|DRUG: IPX054 200 mg Placebo|DRUG: IPX054 250 mg Placebo|DRUG: CD-LD IR Placebo|DRUG: CD-LD CR Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Does Continuous Adductor Canal Nerve Block Improve the Quality of Recovery for Outpatient Total Knee Arthroplasty Patients?
Status: COMPLETED
Conditions: Arthroplasty, Replacement, Knee|Nerve Block|Anesthesia, Regional|Ambulatory Surgical Procedures
Interventions: DRUG: Normal Saline|DRUG: Ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Olfactory Training on Smell Dysfunction Patients in HK
Status: RECRUITING
Conditions: Olfaction Disorders|Smell Disorders|Anosmia|Hyposmia|Olfactory Impairment|Smell Loss|Smell Dysfunction
Interventions: OTHER: Olfactory Training|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Coparenting Intervention to Prevent Postpartum Depression
Status: COMPLETED
Conditions: Postpartum Depression|Anxiety
Interventions: BEHAVIORAL: eHealth Antenatal Coparenting Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effectiveness of Gabapentin for Post-operative Pain Following Cesarean Section
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: lactose|DRUG: Gabapentin 300mg|DRUG: Gabapentin 600mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pneumatic Displacement of Subretinal Hemorrhage With Perfluorocarbon Gases
Status: UNKNOWN
Conditions: Subretinal Hemorrhage and Exudative Maculopathy
Interventions: PROCEDURE: Pneumatic displacement
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Short-term Blinatumomab as a Bridge Therapy for Allo-HSCT in Low Burden B-ALL
Status: RECRUITING
Conditions: Leukemia, Lymphoid
Interventions: DRUG: blinatumomab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testing a Prediction Algorithm Into a Running Telehealth System for Patients With COPD
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease|COPD Exacerbation|COPD Exacerbation Acute|COPD
Interventions: OTHER: Algorithm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Assessment and Treatment of Cognitive Functioning Deficits in Veterans With PTSD
Status: RECRUITING
Conditions: Posttraumatic Stress Disorder
Interventions: BEHAVIORAL: Compensatory Cognitive Training (CCT)|BEHAVIORAL: Treatment as Usual (TAU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Exenatide Plus Pioglitazone Versus Insulin in Poorly Controlled T2DM
Status: UNKNOWN
Conditions: Type 2 Diabetes
Interventions: DRUG: Pioglitazone plus exenatide|DRUG: insulin glargine and insulin aspart
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: WiserAD: The Effect of a Structured Online Intervention on Antidepressant Deprescribing in Primary Care
Status: RECRUITING
Conditions: Depression
Interventions: BEHAVIORAL: WiserAD|BEHAVIORAL: Attention control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Blossom Project: "BlossomUP" Methods to Decrease Sedentary Time in Pregnancy
Status: UNKNOWN
Conditions: Sedentary Lifestyle|Diabetes Mellitus, Gestational
Interventions: OTHER: Limit accumulation of sedentary time|OTHER: Walk|OTHER: Normal daily routine; Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Mind Over Matter for Black and African American Women: A Single Arm Trial Examining Feasibility and Acceptability of a Supportive Intervention
Status: ACTIVE_NOT_RECRUITING
Conditions: Cancer|Breast Cancer|Brain Cancer|Central Nervous System Cancer|Colorectal Cancer|Esophageal Cancer|Gynecologic Cancer|Head and Neck Cancer|Gastrointestinal Cancer|Genitourinary Cancer|Melanoma|Blood Cancer|Lung Cancer|Acceptance and Commitment Therapy|Mind-Body Therapies|Psychosocial Intervention
Interventions: OTHER: Mind Over Matter (MOM)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Periodontal Therapy in Coronary Artery Patients
Status: COMPLETED
Conditions: Cardiovascular Diseases|Atheroma|Coronary Artery Disease
Interventions: DEVICE: Subgingival scaling and root planing|DEVICE: Oral prophylaxis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Randomized Comparative Study of a Weekly Versus Every Other Week Nurse Practitioner-led Symptom Management Clinic for Head and Neck Cancer Patients Undergoing Concurrent Chemotherapy and Radiation
Status: WITHDRAWN
Conditions: Head and Neck Cancer
Interventions: OTHER: Nurse Practitioner Clinic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Intranasal Sedation With Dexmedetomidine and Ketamine in Pediatric Dentistry (NASO II)
Status: COMPLETED
Conditions: Caries of Infancy|Dental Anxiety
Interventions: DRUG: Dexmedetomidine Hydrochloride|DRUG: Ketamine Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prostaglandin E1 in Outpatients With Intermittent Claudication
Status: COMPLETED
Conditions: Stage II Peripheral Arterial Occlusive Disease|Intermittent Claudication Fontaine Stage II PAOD
Interventions: DRUG: Alprostadil (Prostaglandin E1)|DRUG: Pentoxifylline|DRUG: Placebo to Pentoxifylline oral|DRUG: Placebo to Alprostadil (Prostaglandin E1) intravenous
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Effect of Iodized Oil Supplementation During Infancy
Status: COMPLETED
Conditions: Iodine Deficiency
Interventions: DIETARY_SUPPLEMENT: Iodized oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of Efficacy of Intralesional Triamcinolone Injection and Clobetasol Propionate Ointment for Psoriatic Nails
Status: COMPLETED
Conditions: Psoriatic Nails
Interventions: DRUG: 0.1% triamcinolone , 0.05% clobetasol propionate ointment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Length of Hospital Stay, Nursing Hours and Recovery After Laparoscopic Versus Open Colon Resection Without Fast Track
Status: TERMINATED
Conditions: Sigmoid Neoplasms
Interventions: PROCEDURE: laparoscopic colonic resection|PROCEDURE: laparoscopic sigmoid resection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: 12 Week Study Of PF-00734200 For The Treatment Of Type 2 Diabetes Mellitus In Subjects Treated With Metformin
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Placebo|DRUG: PF-00734200 10 mg QD|DRUG: PF-00734200 20 mg QD|DRUG: PF-00734200 5 mg QD|DRUG: PF-00734200 2 mg QD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective, Randomized Clinical Trial Comparing Early Versus Delayed Postoperative Mobilization After Arthroscopic Rotator Cuff Tear Reapair.
Status: UNKNOWN
Conditions: Rotator Cuff Tear Repair
Interventions: OTHER: Standard rehabilitation program|OTHER: Early rehabilitation program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of NanoDOX Hydrogel vs Placebo for Dehisced Surgical Wounds
Status: WITHDRAWN
Conditions: Dehisced Surgical Wounds
Interventions: DRUG: NanoDOX 1% doxycycline monohydrate Hydrogel|DRUG: placebo hydrogel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Vibegron in Pediatric Participants 2 Years to Less Than (<) 18 Years of Age With NDO and on CIC
Status: RECRUITING
Conditions: Neurogenic Detrusor Overactivity
Interventions: DRUG: Vibegron
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Cardioprotective Effect of Intralipid in Decreasing the Ischemic Insults During Off-pump Coronary Artery Revascularization
Status: COMPLETED
Conditions: Anesthesia
Interventions: DRUG: Intralipid|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Needs and Preferences of Patients With Head-neck Cutaneous SCC
Status: ACTIVE_NOT_RECRUITING
Conditions: Cutaneous Squamous Cell Carcinoma|Cutaneous Squamous Cell Carcinoma of the Head and Neck|Squamous Cell Carcinoma|Squamous Cell Carcinoma of Head and Neck|Squamous Cell Carcinoma of the Head and Neck|Skin Cancer|Patient Satisfaction|High-Risk Cancer|Preference, Patient|Decision Making|Interview
Interventions: OTHER: Regular care with additional administration of a semi-structured interview
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Open Versus Laparoscopic Left Hepatic Sectionectomy
Status: UNKNOWN
Conditions: Hepatolithiasis|Laparoscopic Liver Resection|Open Liver Resection|Enhanced Recovery
Interventions: PROCEDURE: laparoscopic hepatic sectionectomy|PROCEDURE: open left hepatic sectionectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: n-CPAP Versus n-BiPAP and NIPPV for Postextubation in RDS in Preterms
Status: COMPLETED
Conditions: Respiratory Distress Syndrome
Interventions: DEVICE: N-CPAP|DEVICE: n-BiPAP|DEVICE: NIPPV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multi-modality Imaging of Ischemia With 18F-FDG PET and CTA
Status: TERMINATED
Conditions: Myocardial Ischemia
Interventions: RADIATION: PET MPI imaging with 18F-Fluorodeoxyglucose
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Ethically Accepted With Code 851/2971 A Comparison of Class Ⅱ Malocclusion Treatment Using Van Beek-headgear Activator Versus Andresen Activator
Status: ENROLLING_BY_INVITATION
Conditions: Class II Growth Modification
Interventions: DEVICE: Van-Beek activator and a headgear|DEVICE: Andresen activator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of SB-509 in Subjects With Diabetic Neuropathy
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1|Diabetes Mellitus, Type 2|Diabetic Polyneuropathy
Interventions: DRUG: SB-509|OTHER: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Safety and Efficacy Study of NAC in Patients With TA-TMA
Status: COMPLETED
Conditions: Thrombotic Microangiopathies|Hematologic Diseases
Interventions: DRUG: N-Acetylcysteine|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Effects of Hepatic Impairment on the Pharmacokinetics of Relacorilant
Status: COMPLETED
Conditions: Hepatic Impairment
Interventions: DRUG: Relacorilant
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER