pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Evaluation Of Anchorage Control During Canine Retraction Using Arch Wire Stopper Versus Mini-Screws
Status: RECRUITING
Conditions: Orthodontic Appliance Complication
Interventions: DEVICE: archwire stopper mesial to the maxillary first molar group|DEVICE: inter-radicular mini-screw
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating E2007 (Perampanel) in Patients With Painful Diabetic Neuropathy (PDN) or Post-Herpetic Neuralgia (PHN)
Status: COMPLETED
Conditions: Neuralgia
Interventions: DRUG: E2007
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cognitive and Balance Dual Task Training for People With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia|Cognition|Balance|Dual Task|Mental Illness|Psychiatric Disorder|Fall Prevention
Interventions: BEHAVIORAL: cognitive and balance dual task training|BEHAVIORAL: balance training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Study Using TRIMELVax for Stage IIIC / IV Melanoma Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Melanoma Stage IIIc|Melanoma Stage IV
Interventions: BIOLOGICAL: TRIMELVAX
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Efficient Lifestyle Counseling Method on the Risks of Cardiovascular Disease in Health Care Center Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Obesity
Interventions: BEHAVIORAL: Group counseling|BEHAVIORAL: Intensive group counseling|BEHAVIORAL: Persuasive ICT support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neointimal Coverage After Implantation of Biolimus Eluting Stent With Biodegradable Polymer: Optical Coherence Tomographic Assessment According to the Treatment of Dyslipidemia and Hypertension and the Types of Implanted Drug-eluting Stents
Status: COMPLETED
Conditions: Stable Angina or Acute Coronary Syndrome Considered for Percutaneous Coronary Intervention With Dyslipidemia or Hypertension
Interventions: DEVICE: Sirolimus-eluting stent|DEVICE: Biolimus-eluting stents|DRUG: pravastatin 20mg/day after DES implantation|DRUG: pitavastatin 2mg/day after DES implantation|DRUG: Non-ARB /day after DES implantation|DRUG: Eposartan 600mg/day after DES implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effect of a Postural Reflex Rehabilitation Program on a Foam Surface on Stress Urinary Incontinence in Women
Status: UNKNOWN
Conditions: Urinary Incontinence,Stress
Interventions: OTHER: intervenions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Intervention for Emotions in Caregivers of Dementia
Status: NOT_YET_RECRUITING
Conditions: BPSD|Expressed Emotion|Depressive Symptoms
Interventions: BEHAVIORAL: Caregivers Of dementia Processing Emotions (COPE) program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Dupilumab in Adult Patients With Extrinsic Moderate-to-Severe Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: Placebo|DRUG: Dupilumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Single-dose Cross-over Study to Assess Direct and Indirect Effects of Dapagliflozin on Pancreatic Alpha and Beta Cells in Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Dapagliflozin|DRUG: Saxagliptin|DRUG: Glucose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Evaluate the Efficacy of an Anti-Fungal Supplement
Status: COMPLETED
Conditions: Candida Systemic|Candida Albicans Infection|Candida Infection
Interventions: DIETARY_SUPPLEMENT: CanXida Remove (Formula RMV)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Primary and Secondary Prevention of Human Papillomavirus (HPV) Disease in China
Status: UNKNOWN
Conditions: HPV Infections|Precancerous Disease of the Cervix|Cervical Cancer|HPV Related Diseases
Interventions: BIOLOGICAL: Gardasil (VLP, HPV Quadrivalent prophylactic vaccine)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of add-on Apremilast Versus add-on Methotrexate in Patients With Oral Lichen Planus
Status: NOT_YET_RECRUITING
Conditions: Oral Lichen Planus
Interventions: DRUG: Prednisolone|DRUG: Apremilast|DRUG: Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Prospective, Single-center, One-arm Clinical Study of Apatinib Combined With Chemotherapy for Pretreated Patients With Advanced Small Cell Lung Cancer
Status: COMPLETED
Conditions: Small-cell Lung Cancer
Interventions: DRUG: Apatinib|DRUG: chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Resistant Maltodextrin for Gut Microbiome in Parkinson's Disease: Safety and Tolerability Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Parkinson Disease|Intestinal Bacteria Flora Disturbance|Dietary Modification
Interventions: DIETARY_SUPPLEMENT: Resistant maltodextrin|DIETARY_SUPPLEMENT: maltodextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A New Spinal Brace Design Concept for the Treatment of Adolescent Idiopathic Scoliosis
Status: TERMINATED
Conditions: Adolescent Idiopathic Scoliosis
Interventions: DEVICE: 3D Printed Brace
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: European Multicenter, Randomized, Comparative Efficacy/Safety Study of the Mar-Tyn TiN-Coated Stent
Status: UNKNOWN
Conditions: Coronary Artery Disease|Angioplasty, Transluminal, Percutaneous Coronary|Stents
Interventions: DEVICE: Mar-Tyn TiN coated Co-Cr Numen stent implant|DEVICE: Vision Co-Cr stent implant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Proof-of-Concept Trial of a Positive Psychology Intervention for Allogeneic Stem Cell Transplant Patients
Status: COMPLETED
Conditions: Hematologic Malignancy|Hematopoietic/Lymphoid Cancer|Blood Cancer
Interventions: BEHAVIORAL: Positive Psychology Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Prospective Study of UDP-gluconoryltransferase 2B17 Genotype as a Predictive Marker of Exemestane PK and PD
Status: UNKNOWN
Conditions: Breast Carcinoma
Interventions: DRUG: Exemestane
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Safety of HCQ Plus Pred in ANA Positive ITP
Status: RECRUITING
Conditions: Immune Thrombocytopenia With Positive ANA Antibodies
Interventions: DRUG: Hydroxychloroquine Oral Tablet|DRUG: Prednisone tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Photodegraded Edible Food Dyes
Status: WITHDRAWN
Conditions: Thyroid; Functional Disturbance
Interventions: DIETARY_SUPPLEMENT: Erythrosine, prepared in drinking water (0.69 mg/kg bw/day)|DIETARY_SUPPLEMENT: SODIS-treated erythrosine, prepared in drinking water (0.69 mg/kg bw/day)|DIETARY_SUPPLEMENT: Iodine, prepared in drinking water 0.075 mg/kg bw/day)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Conversion of Hyperglycemic Patients Being Treated With Intravenous Insulin Infusions to Lantus Insulin
Status: COMPLETED
Conditions: Hyperglycemia|Diabetes
Interventions: DRUG: insulin glargine|DRUG: insulin glargine|DRUG: insulin glargine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Huperzine A on Cognitive Function and Perception of Effort During Exercise
Status: COMPLETED
Conditions: Cognitive Enhancement During Exercise
Interventions: OTHER: Huperzine A|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Feasibility of Two New Software Modules for the Rehabilitation of Patients With Neuromuscular Upper Limb Impairments
Status: WITHDRAWN
Conditions: Stroke|Parkinson Disease|Traumatic Brain Injury|Guillain-Barre Syndrome
Interventions: OTHER: VR-based training including AO and MI
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Investigation of the Femoral Shortening Osteotomy in the Developmental Dislocation of the Hip (FSODDH)
Status: UNKNOWN
Conditions: Hip Dislocation|Femur Head Necrosis
Interventions: PROCEDURE: Osteotomy|PROCEDURE: Non-osteotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Impact of Genetic Counseling for Individuals With Mental Illness
Status: COMPLETED
Conditions: Schizophrenia|Bipolar Disorder|Schizoaffective Disorder
Interventions: BEHAVIORAL: Genetic Counseling|BEHAVIORAL: Educational Booklet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: The Effect of Valacyclovir on the Detection of HIV From Genital Herpes Lesions in HIV-Infected Patients
Status: COMPLETED
Conditions: Herpes Simplex|HIV Infections
Interventions: DRUG: Valacyclovir hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: The Impact of a Technology-enabled Decision Aid, for Patients With Hip and Knee Osteoarthritis on Decision Quality, Level of Shared Decision-making, Patient Satisfaction and Magnitude of Limitations
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: OTHER: OM1 Dell Shared Decision Making Tool|OTHER: Education material from OM1 Dell Shared Decision Making Tool
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: CBD for Dental Pain
Status: COMPLETED
Conditions: Odontalgia|Toothache
Interventions: DRUG: Epidiolex 100 mg/mL Oral Solution|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Bazedoxifene for Prevention of Glucocorticoid-induced Bone Loss in RA Patients
Status: COMPLETED
Conditions: Arthritis, Rheumatoid
Interventions: DRUG: Bazedoxifene|DRUG: Calcium/Vit D
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Traditional Dorsal Digital Block vs Volar Subcutaneous Digital Block
Status: ACTIVE_NOT_RECRUITING
Conditions: Hand Injuries
Interventions: PROCEDURE: Volar digital block with lidocaine|PROCEDURE: Volar digital block with saline|PROCEDURE: Dorsal digital block with lidocaine|PROCEDURE: Dorsal digital block with saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Modeling the Effects of Vocal Cord Atrophy on Airflow and Voice Quality in Elderly Individuals
Status: WITHDRAWN
Conditions: Vocal Cord Atrophy
Interventions: OTHER: Cone Beam Computed Tomography|DIAGNOSTIC_TEST: Acoustic/Auerodynamic testing|DIAGNOSTIC_TEST: Laryngovideostroboscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The LISA (Lactoferrin InStead of Antibiotics/Antifungals) Feasibility Study
Status: NOT_YET_RECRUITING
Conditions: Bacterial Vaginosis|Candida Vaginal
Interventions: OTHER: Vaginal lactoferrin|DRUG: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Paricalcitol Compared to Maxacalcitol in Chronic Kidney Disease Patients With Secondary Hyperparathyroidism
Status: COMPLETED
Conditions: Secondary Hyperparathyroidism|Hemodialysis
Interventions: DRUG: paricalcitol|DRUG: maxacalcitol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy With or Without Total-Body Irradiation Followed By Stem Cell Transplant in Treating Patients With Non-Hodgkin Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: DRUG: carmustine|DRUG: cyclophosphamide|DRUG: etoposide|PROCEDURE: autologous hematopoietic stem cell transplantation|PROCEDURE: peripheral blood stem cell transplantation|RADIATION: total-body irradiation|DRUG: G-CSF
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Meniscal Repair Biologic Augmentation: Marrow Venting Procedure Versus PRP (MVP Trial)
Status: UNKNOWN
Conditions: Meniscal Tear
Interventions: OTHER: Bone marrow venting procedure (BMVP)|OTHER: Platelet Rich Plasma (PRP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Clinical Decision Rule Validation Study to Predict Low Recurrent Risk in Patients With Unprovoked Venous Thromboembolism
Status: COMPLETED
Conditions: Idiopathic Venous Thromboembolism
Interventions: OTHER: Application of the"Men continue and HER DOO2" rule
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Corticosteroid Therapy of Septic Shock - Corticus
Status: COMPLETED
Conditions: Shock, Septic
Interventions: DRUG: hydrocortisone sodium succinate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: High Altitude (HA) Residents With High Altitude Pulmonary Hypertension (HAPH), Pulmonary Artery Pressure (PAP) Assessed at HA (3200 m) vs LA (760 m)
Status: NOT_YET_RECRUITING
Conditions: High Altitude Pulmonary Hypertension
Interventions: OTHER: Echocardiography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Effect of Training Prepared in Line With Fracture Liaison Service Model on Frailty in Hip Surgery Patients
Status: RECRUITING
Conditions: Geriatric Patients
Interventions: OTHER: Training Prepared in Line with the Fracture Liaison Service Model
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Study of Aortic Root Reimplantation Procedure
Status: COMPLETED
Conditions: Ascending Aortic Aneurism|Aortic Valve Insufficiency
Interventions: PROCEDURE: Aortic Root Reimplantation Procedure|PROCEDURE: Aortic Valve Reimplantation Procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effects on the Awakening With Laryngeal Mask vs Endotracheal Tube in Endoscopic Endonasal Transsphenoidal Base Surgery
Status: COMPLETED
Conditions: Skull Base Neoplasms
Interventions: DEVICE: endotracheal tube|DEVICE: Laryngeal mask
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Namodenoson in the Treatment of Advanced Hepatocellular Carcinoma in Patients With Child-Pugh Class B7 Cirrhosis
Status: RECRUITING
Conditions: Hepatocellular Carcinoma|Cirrhosis
Interventions: DRUG: Namodenoson|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Aromatherapy to Reduce Pain and Anxiety During Cervical Colposcopy
Status: COMPLETED
Conditions: Colposcopy
Interventions: OTHER: Essential Lavender Oil|OTHER: Lavender Scent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: SENSE Study: Remote Symptom Monitoring for Patients With Chemotherapy-induced Peripheral Neuropathy
Status: ENROLLING_BY_INVITATION
Conditions: Chemotherapy-induced Peripheral Neuropathy
Interventions: BEHAVIORAL: Mobile Ecological Momentary Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of Tamoxifen on Clinical Outcome in Women With Thin Endometrium Undergoing Frozen Thawed Cycle.
Status: UNKNOWN
Conditions: Endometrium
Interventions: DRUG: Tamoxifen|DRUG: estradiol valerate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Single Group Study of Empower@Home-an Internet Cognitive Behavioral Therapy Intervention
Status: COMPLETED
Conditions: Depression|Depressive Disorder|Behavioral Symptoms|Mood Disorders|Mental Disorders
Interventions: BEHAVIORAL: Empower@Home
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GSK2894512 Vehicle-Controlled Study for Adult Plaque Psoriasis
Status: WITHDRAWN
Conditions: Psoriasis
Interventions: DRUG: GSK2894512 1% cream|DRUG: Vehicle cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Antagonist/Letrozole in Poor Responders
Status: COMPLETED
Conditions: Ovarian Stimulation
Interventions: DRUG: letrozole|DRUG: oral contraceptive (Marvelone)|DRUG: GnRH agonist (buserelin)|DRUG: recombinant FSH or hMG|DRUG: ganirelix acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: NAFLD and Liver Fibrosis in Obese Adolescents
Status: COMPLETED
Conditions: Liver Fibrosis|Liver Steatosis|Weight Loss
Interventions: PROCEDURE: laparoscopic sleeve gastrectomy (LSG) and laparoscopic single anastomosis gastric bypass (LSAGB)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Turmeric and Turmeric-containing Tablets and Sebum Production
Status: COMPLETED
Conditions: Skin Inflammation
Interventions: DIETARY_SUPPLEMENT: Turmeric|DIETARY_SUPPLEMENT: Turmeric-containing combination tablet|DIETARY_SUPPLEMENT: Placebo tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Su-Huang Antitussive Capsule on Cough Variant Asthma
Status: UNKNOWN
Conditions: Asthma
Interventions: DRUG: Su-Huang antitussive capsule|DRUG: Sugar pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Essential Surgical Skills-Emergency Maternal and Child Health Training
Status: COMPLETED
Conditions: Sepsis|Asthma|Heart Failure|Seizure|Coma
Interventions: BEHAVIORAL: ESS-EMCH training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: The Tapering Dose of Luspatercept in Patients With Lower-risk Myelodysplastic Syndromes
Status: RECRUITING
Conditions: Lower Risk MDS Per IPSS-R
Interventions: DRUG: Luspatercept
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy at 24 Weeks and Safety, Tolerability and Long Term Efficacy of Secukinumab (AIN457) in Patients With Active Rheumatoid Arthritis (RA) and an Inadequate Response to Anti-Tumor Necrosis Factor α (Anti-TNFα) Agents (CAIN457F2309 and CAIN457F2309E1)
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: BIOLOGICAL: AIN457|BIOLOGICAL: Placebo|BIOLOGICAL: Abatacept
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rilonacept for Treatment of Cryopyrin-Associated Periodic Syndromes (CAPS)
Status: COMPLETED
Conditions: Familial Cold Autoinflammatory Syndrome (FCAS)|Familial Cold Urticaria|Muckle-Wells Syndrome (MWS)|Genetic Diseases, Inborn
Interventions: DRUG: rilonacept 160 mg|DRUG: Placebo|DRUG: rilonacept 160 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Incidence of Postoperative Residual Neuromuscular Blockade in Portugal
Status: COMPLETED
Conditions: Residual Neuromuscular Blockade|Residual Paralysis, Post-Anesthesia|Observational Study|Complication of Anesthesia|Neuromuscular Blockade
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Inflation on the Angiographic Result After Balloon Angioplasty in the Femoropopliteal Segment
Status: UNKNOWN
Conditions: Femoropopliteal Arterial Stenosis
Interventions: PROCEDURE: Balloon dilation during 180 seconds|PROCEDURE: Balloon dilation during 300 seconds
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: NIA_Improving Function and Well-being by Improving Patient Memory: Transdiagnostic Sleep and Circadian Treatment
Status: RECRUITING
Conditions: Sleep Disorder|Circadian Dysregulation|Memory Impairment
Interventions: BEHAVIORAL: Memory Support Intervention|BEHAVIORAL: Transdiagnostic Intervention for Sleep and Circadian Dysfunction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vaginal Hysterectomy Versus Laparoscopically Assisted Vaginal Hysterectomy for Large Uteri
Status: UNKNOWN
Conditions: Minimally Invasive Hysterectomy in Large Uteri
Interventions: PROCEDURE: Vaginal hysterectomy|PROCEDURE: Laparoscopic assisted vaginal hysterectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating the Safety, Efficacy, and Pharmacodynamic Effects of ABT-981 in Patients With Knee Osteoarthritis
Status: COMPLETED
Conditions: Knee Osteoarthritis|Medial Compartment Knee Osteoarthritis
Interventions: BIOLOGICAL: ABT-981|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cardiac Arrhythmia Pilot Study (CAPS)
Status: COMPLETED
Conditions: Arrhythmia|Cardiovascular Diseases|Heart Diseases|Ventricular Arrhythmia
Interventions: DRUG: encainide|DRUG: moricizine|DRUG: flecainide|DRUG: imipramine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Beyond Bias - Reducing Provider Bias Towards Adolescents to Increase Contraception Take-Up in Tanzania, Burkina Faso, and Pakistan
Status: COMPLETED
Conditions: Family Planning Services
Interventions: OTHER: Beyond Bias Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Efficacy and Safety of LCZ696 in Comparison to Olmesartan in Japanese Patients With Essential Hypertension
Status: COMPLETED
Conditions: Essential Hypertension
Interventions: DRUG: LCZ696|DRUG: Olmesartan|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dose-Escalating Study Of SB-485232 Administered Intravenously Every 28 Days To Adults With Solid Tumors Or Lymphomas
Status: COMPLETED
Conditions: Solid Tumor Cancer|Lymphoma
Interventions: DRUG: SB-485232
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Brachial Artery Dilatation, Uterine Artery Doppler, Umbilical Artery Doppler and 1st-trimester Visceral Adipose Tissue Measurement in Obese and Normal Pregnant Women
Status: COMPLETED
Conditions: Obese|Vascular Diseases|Pregnancy Related|Visceral Obesity
Interventions: OTHER: ultrasonography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Managment and Outcome of Urinary Bladder Trauma After Gynaecological and Obstetric Operations
Status: NOT_YET_RECRUITING
Conditions: Urinary Bladder Trauma
Interventions: PROCEDURE: Surgical managment of Urinary bladder trauma after gynaecological and obstetric operation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Patients With Major Depressive Disorder and Residual Apathy
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: Duloxetine|DRUG: Escitalopram
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II Clinical Trial of Safety and Immunogenicity of Recombinant Subunit Tuberculosis Vaccine GamTBvac
Status: COMPLETED
Conditions: Healthy
Interventions: BIOLOGICAL: GamTBvac vaccine|BIOLOGICAL: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: ELRR by TEM Versus Laparoscopic TME in iT2N0M0 SMALL LOW RECTAL CANCER
Status: COMPLETED
Conditions: Rectal Cancer
Interventions: PROCEDURE: ELRR BY TEM|PROCEDURE: LTME
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 2c Dose Comparison Study of MP4OX in Trauma
Status: WITHDRAWN
Conditions: Trauma|Hemorrhagic Shock|Lactic Acidosis
Interventions: DRUG: MP4OX|DRUG: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ruxolitinib and Decitabine for High Risk Hematological Malignancies
Status: RECRUITING
Conditions: Peripheral Blood Stem Cell Transplantation
Interventions: DRUG: modified By/Cy conditioning regimen intensified by Ruxolitinib and Decitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dynamic Whole Body Positron Emission Tomography/Computed Tomography Imaging
Status: UNKNOWN
Conditions: Neuroendocrine Tumors|Prostate Cancer|Prostatic Neoplasms|Carcinoid Tumor|Paraganglioma|Neuroblastoma
Interventions: DIAGNOSTIC_TEST: 18F-FDG PET/CT|DIAGNOSTIC_TEST: 68Ga-DOTATOC PET/CT|DIAGNOSTIC_TEST: 18F-DCFPyL PET/CT
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of AMG 181 in Healthy Subjects and Subjects With Mild to Moderate Ulcerative Colitis
Status: TERMINATED
Conditions: Ulcerative Colitis
Interventions: DRUG: Amg 181
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of FEETME® Soles and GAITRITE® Walkway for the Evaluation of Gait Disorders in CIDP.
Status: RECRUITING
Conditions: Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)
Interventions: OTHER: Clinical examination|OTHER: Functional scales|DIAGNOSTIC_TEST: Walking test
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Pilot Study to Test the Feasibility and the Efficacy of the German Language Adapted PRO-SELF© Plus Pain Control Program
Status: COMPLETED
Conditions: Neoplasm Metastasis
Interventions: BEHAVIORAL: German PRO-SELF(c) Plus Pain Control Program (PCP)|OTHER: Standard Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Single-Session "Empowered Relief" Class for Marfan Syndrome and Related Conditions
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Pain|Marfan Syndrome|Vascular Ehlers-Danlos Syndrome|Loeys-Dietz Syndrome
Interventions: BEHAVIORAL: Empowered Relief
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Safety, Tolerability and Immune Response Following Vaccination With Immunose™ FLU in Older Adults
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Immunose™ FLU 1%|BIOLOGICAL: Immunose™ FLU 2%, 200 μl|BIOLOGICAL: Immunose™ FLU 2%, 300 μl|BIOLOGICAL: Influenza antigen|DRUG: Placebo|BIOLOGICAL: i.m comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Implanted Myoelectric Control for Restoration of Hand Function in Spinal Cord Injury
Status: ACTIVE_NOT_RECRUITING
Conditions: Spinal Cord Injury|Tetraplegia
Interventions: DEVICE: IST-12
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate an Immunomodulatory Therapy in Adult Patients With Perennial Allergic Rhinoconjunctivitis
Status: COMPLETED
Conditions: Perennial Allergic Rhinoconjunctivitis|House Dust Mite Allergy
Interventions: DRUG: CYT005-AllQbG10 (combination of house dust mite allergen extract with CYT003-QbG10)|DRUG: House dust mite allergen extract in combination with CYT003-QbG10-placebo|DRUG: CYT003-AllQbG10 in combination with house dust mite allergen extract placebo|DRUG: CYT003-QbG10-placebo in combination with house dust mite allergen extract placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Study to Assess the Safety of NLY01 in Healthy Subjects
Status: COMPLETED
Conditions: Safety and Tolerability in Healthy Volunteers
Interventions: DRUG: NLY01
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effect of Vagus Nerve Stimulation in Patients Undergoing VT Ablation
Status: COMPLETED
Conditions: Arrhythmia|Ventricular Tachycardia (VT)
Interventions: OTHER: Vagus Nerve Stimulation (VNS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluate The Utility Of 124I-cG250 for The Early Detection Of Response to Therapy In Patients With Metastatic Renal Cell Carcinoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Renal Cancer
Interventions: DRUG: 124IcG250
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Brain Ketone Body Challenge Imaging Study
Status: WITHDRAWN
Conditions: Alzheimer Disease
Interventions: DIETARY_SUPPLEMENT: Challenge A - low calorie Ensure®|DIETARY_SUPPLEMENT: Challenge B - Ensure® plus ketone esters (KE)|PROCEDURE: PET Scan|BEHAVIORAL: Cognitive Testing - FCSRT|BEHAVIORAL: Story Recall|BEHAVIORAL: BVRT|BEHAVIORAL: CogState One Card Learning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Learn About the Study Medicine (Called Ontorpacept or TTI-621) Given Alone and in Combination With Doxorubicin in People With Leiomyosarcoma
Status: TERMINATED
Conditions: Leiomyosarcoma
Interventions: DRUG: Ontorpacept (TTI-621)|DRUG: Doxorubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Retrospective Evaluation of Clinical and Radiographic Outcomes Following Total Talus Replacement
Status: COMPLETED
Conditions: Talus|Ankle Arthropathy
Interventions: PROCEDURE: Total Talus Replacement (TTR)|PROCEDURE: Total Ankle Total Talus Replacement (TATTR)|PROCEDURE: Total Ankle Total Talus Replacement + Subtalar Fusion (TATTR + STJ)|PROCEDURE: Total Talus Replacement + Subtalar Fusion (TTR + STJ)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Dose Escalation and Expansion Study of GIGA-564 in Participants With Locally Advanced or Metastatic Solid Tumor Malignancies
Status: RECRUITING
Conditions: Advanced or Metastatic Solid Tumor Malignancies
Interventions: DRUG: GIGA-564|DRUG: GIGA-564
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mediterranean Diet- and Psychological Well-being Theory-based Intervention to Reverse Metabolic Syndrome in Chile
Status: UNKNOWN
Conditions: Metabolic Syndrome
Interventions: BEHAVIORAL: Low fat diet|BEHAVIORAL: Mediterranean diet|BEHAVIORAL: Mediterranean diet plus psychological well-being support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lapatinib in Treating Patients With Advanced or Metastatic Breast Cancer That Overexpresses HER2
Status: COMPLETED
Conditions: Breast Cancer|Metastatic Cancer
Interventions: DRUG: lapatinib ditosylate|GENETIC: gene expression analysis|OTHER: diagnostic laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Retrieval of Displaced Root in the Maxillary Sinus Via Lateral Bony Window Using the Piezoelectric Device
Status: COMPLETED
Conditions: Oroantral Fistula|Displaced Tooth
Interventions: DEVICE: lateral bony window
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: In Vitro Fertilisation Versus Intracytoplasmic Sperm Injection in Patients Without Severe Male Factor Infertility
Status: ACTIVE_NOT_RECRUITING
Conditions: Infertility
Interventions: PROCEDURE: IVF|PROCEDURE: ICSI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Evaluation AZD2014 Alone and in Combination With Rituximab in Relapsed/Refractory Diffuse Large B Cell Lymphoma
Status: COMPLETED
Conditions: Diffuse Large B-Cell Lymphoma
Interventions: DRUG: AZD 2014|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Melatonin Oral Gel for Oral Mucositis in Patients With Head and Neck Cancer Undergoing Chemoradiation
Status: COMPLETED
Conditions: Oral Mucositis
Interventions: DRUG: Melatonin oral gel 3%|DRUG: Placebo oral gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Phase 1 Study of CK-301 (Cosibelimab) as a Single Agent in Subjects With Advanced Cancers
Status: RECRUITING
Conditions: Lung Neoplasms|Carcinoma, Non-Small-Cell Lung|Carcinoma, Small Cell|Malignant Mesothelioma, Advanced|Head and Neck Cancer|Melanoma|Merkel Cell Carcinoma|Renal Cell Carcinoma|Urothelial Carcinoma|Classical Hodgkin Lymphoma|Cutaneous Squamous Cell Carcinoma|Non Hodgkin Lymphoma|Endometrial Cancer
Interventions: DRUG: CK-301 (cosibelimab)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevention and Treatment of Epstein-Barr Virus (EBV) Lymphoma Following a Solid Organ Transplant Using EBV Specific Cytotoxic T Lymphocytes (CTLs).
Status: COMPLETED
Conditions: Epstein-Barr Virus Infections|Lymphoproliferative Disorders
Interventions: BIOLOGICAL: Intravenous injection of EBV specific CTLs
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigating Biological Targets, Markers, and Intervention for Chronic Pain
Status: COMPLETED
Conditions: Chronic Pain|Pain, Chronic|Pain Syndrome|Pain, Neuropathic|Pain, Intractable
Interventions: BEHAVIORAL: Mindfulness Based Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of Absorbability Between Calcium Tablet and Calcium Ion Water
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Calcium tablet|DIETARY_SUPPLEMENT: Calcium ion water (250mg)|DIETARY_SUPPLEMENT: Calcium ion water (125mg)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Heterogeneously Hypofractionated Radiotherapy for Locally Advanced NSCLC
Status: NOT_YET_RECRUITING
Conditions: Non-small Cell Lung Cancer Stage III|Radiotherapy Side Effect|Frailty
Interventions: RADIATION: Photon|RADIATION: Proton
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized, Double-Blind, Parallel-Group, Vehicle-Controlled, Multicenter Study Comparing Diclofenac Sodium Gel, 3% to Solaraze® Gel, 3% in the Treatment of Actinic Keratosis on the Face or Bald Scalp
Status: COMPLETED
Conditions: Actinic Keratosis
Interventions: DRUG: Diclofenac sodium|DRUG: Diclofenac sodium|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Oxidative Stress In Stargardt Disease, Age Related Macular Degeneration and Diabetic Retinopathy
Status: TERMINATED
Conditions: Stargardt Disease|Diabetic Retinopathy|Macular Degeneration (Age Related)
Interventions: OTHER: Anterior Chamber (AC) Tap
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effects of Kefir on Pediatric Obesity
Status: NOT_YET_RECRUITING
Conditions: Obesity
Interventions: DIETARY_SUPPLEMENT: Kefir peptide|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Adjustable Compression Wrap Versus Compression Sleeve to Control Breast Cancer-related Lymphedema
Status: COMPLETED
Conditions: Breast Cancer Related Lymphedema|Lymphedema, Secondary|Lymphedema of Upper Arm|Breast Neoplasms
Interventions: DEVICE: Adjustable Compression Wrap|DEVICE: Compression Sleeve
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: EDOCH Alternating With DHAP for New Diagnosed Younger MCL
Status: UNKNOWN
Conditions: Mantle Cell Lymphoma
Interventions: DRUG: Etoposide|DRUG: Doxorubicin|DRUG: Dexamethasone|DRUG: Vincristine|DRUG: Cyclophosphamide|DRUG: Cytarabine|DRUG: Cisplatin|DRUG: Rituximab|DRUG: Thalidomide|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: NB1011 Administered by Continuous Infusion in Cancers That Overexpress Thymidylate Synthase (TS)
Status: COMPLETED
Conditions: Tumors
Interventions: DRUG: NB1011
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Osteopathic Treatment on Motor Development of Hypotonic Infants.
Status: RECRUITING
Conditions: Hypotonia
Interventions: OTHER: ostheopathy|OTHER: simulated osteopathic treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Subcutaneous C.E.R.A. for the Maintenance of Hemoglobin Levels in Participants With Chronic Renal Anemia Not on Dialysis.
Status: COMPLETED
Conditions: Anemia
Interventions: DRUG: methoxy polyethylene glycol-epoetin beta [C.E.R.A.]
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunosuppressant Medication Dosed Daily After Kidney Transplant
Status: TERMINATED
Conditions: Kidney Transplant Rejection|Medication Adherence
Interventions: OTHER: Medication Event Monitoring System (MEMS)|DRUG: Once-Daily Tacrolimus extended release
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Trial of SHR-1707 in Healthy Young Adult and Elderly Subjects
Status: COMPLETED
Conditions: Alzheimer Disease
Interventions: DRUG: SHR-1707|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Intraarticular Injection of Tenoxicam and Hyaluronic Acid Versus Platelet-Rich Plasma and Hyaluronic Acid in Temporomandibular Joint Internal Derangement
Status: ACTIVE_NOT_RECRUITING
Conditions: Temporomandibular Joint Internal Derangement
Interventions: DRUG: Tenoxicam Injectable Product|DRUG: Hyaluronic Acid 20 MG/1 ML Injection Gel/Jelly
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Post-marketing Surveillance (PMS) Use-Result Surveillance With SPIKEVAX BIVALENT and SPIKEVAX X Injection.
Status: RECRUITING
Conditions: SARS-CoV-2
Interventions: BIOLOGICAL: SPIKEVAX Bivalent|BIOLOGICAL: SPIKEVAX X
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of BI 1181181 on Midazolam, Warfarin, Omeprazole and Digoxin
Status: WITHDRAWN
Conditions: Healthy
Interventions: DRUG: Omeprazole|DRUG: Warfarin|DRUG: BI 1181181|DRUG: Midazolam|DRUG: Omeprazole|DRUG: BI 1181181|DRUG: Midazolam|DRUG: Midazolam|DRUG: Warfarin|DRUG: BI 1181181|DRUG: Digoxin|DRUG: Digoxin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Does Cricoid Pressure Reduce the Risk of Aspiration?
Status: COMPLETED
Conditions: Microaspiration|Acute Respiratory Distress Syndrome (ARDS)|Hospital Acquired Pneumonia
Interventions: PROCEDURE: Cricoid pressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Trial of Transcatheter Arterial Chemoembolization (TACE) With Sorafenib for Locally Advanced Hepatocellular Carcinoma (HCC)
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Sorafenib|PROCEDURE: TACE (Transcatheter arterial chemoembolization)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial Of Oral Chloral Hydrate Versus Intranasal Dexmedetomidine For Sedated Abr Exams
Status: COMPLETED
Conditions: Sedation
Interventions: DRUG: Chloral Hydrate|DRUG: Dexmedetomidine|OTHER: Oral placebo|OTHER: Intranasal placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Topiramate and Severe Obesity
Status: COMPLETED
Conditions: Obese Children and Adolescents
Interventions: DRUG: Topiramate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tislelizumab Plus Chemotherapy as First-Line Treatment for Advanced Squamous NSCLC With Brain Metastases
Status: UNKNOWN
Conditions: Non-Small Cell Squamous Lung Cancer|Brain Metastases
Interventions: DRUG: Tislelizumab, paclitaxel, Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mirror Therapy and Treadmill Training for Patients With Chronic Stroke
Status: COMPLETED
Conditions: Stroke
Interventions: DEVICE: Mirror Therapy|DEVICE: Placebo Mirror Therapy|DEVICE: Treadmill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT