pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: An Absorption, Distribution, Metabolism, Excretion (ADME) Study of [14C]Subasumstat in Adults With Advanced or Metastatic Solid Tumors
Status: TERMINATED
Conditions: Solid Tumors
Interventions: DRUG: [14C] Subasumstat|DRUG: Subasumstat
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ezetimibe and Atorvastatin vs. Atorvastatin in Patients Age 65 and Older at High Risk for Coronary Heart Disease (CHD)(0653-112)
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DRUG: ezetimibe and atorvastatin|DRUG: atorvastatin|DRUG: Placebo (unspecified)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I/II Study of Recombinant Botulinum Toxin Type A for the Treatment of Moderate to Severe Glabellar Lines
Status: COMPLETED
Conditions: Moderate to Severe Glabellar Lines
Interventions: BIOLOGICAL: YY001|BIOLOGICAL: OnabotulinumtoxinA|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two NN1250 Formulations in Subjects With Type 1 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 1
Interventions: DRUG: insulin degludec|DRUG: insulin degludec
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Performance Evaluation on the Upper Limb Closed Kinetic Chain Test After Scapular Elastic Taping on Jiu Jitsu Practitioners
Status: UNKNOWN
Conditions: Healthy
Interventions: OTHER: Elastic Tapping
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Assessment of the Effects of Long-term Lipid-lowering Therapy in Patients With Primary STEMI or NSTEMI
Status: RECRUITING
Conditions: Myocardial Infarction, Acute|Myocardial Strain|Arterial Stiffness|Quality of Life
Interventions: DRUG: Atorvastatin 80mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pediatrics Anal Fissures Treatment With Polyethylene Glycol
Status: UNKNOWN
Conditions: Fissure in Ano
Interventions: DRUG: Polyethylene glycol|DRUG: Polyethylene glycol with Diltiazem
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mini- Percutaneous Nephrolithotomy Versus Extracorporeal Shock Wave Lithotripsy for High Density Renal Stones
Status: COMPLETED
Conditions: Renal Stone|Extracorporeal Shockwave Lithotripsy|Percutaneous Nephrolithotomy
Interventions: PROCEDURE: mini-PNL|PROCEDURE: SWL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: HAIC Combined With PD-1 Inhibitor in Potentially Resectable Locally Advanced HCC
Status: ACTIVE_NOT_RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: COMBINATION_PRODUCT: HAIC+PD1|DRUG: HAIC
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Nangibotide in Patients With COVID-19 Receiving Ventilatory Support
Status: COMPLETED
Conditions: COVID19
Interventions: DRUG: nangibotide|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating the Bioavailability of Two Formulations of Linifanib and Food Effect on Pharmacokinetics of Linifanib in Subjects With Advanced or Metastatic Solid Tumors
Status: TERMINATED
Conditions: Advanced or Metastatic Solid Tumors
Interventions: DRUG: linifanib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: tDCS on Parkinson's Disease Cognition
Status: RECRUITING
Conditions: Parkinson Disease|Mild Cognitive Impairment
Interventions: DEVICE: High-definition transcranial direct current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: "Chou's Tiaoshen" Acupoints for Short-term Insomnia.
Status: NOT_YET_RECRUITING
Conditions: Short-term Insomnia
Interventions: OTHER: Acupuncture|DRUG: Estazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing Pressure Versus Simple Adhesive Dressing After Mohs Reconstruction
Status: COMPLETED
Conditions: Non-melanoma Skin Cancer
Interventions: OTHER: Pressure Dressing|OTHER: Simple Adhesive Dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of the Effect of Online Physical Exercise and Computerized Cognitive Stimulation in Patients With Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer Disease|Telerehabilitation|Online Physical Exercise|Computerized Cognitive Stimulation|Covid-19 Pandemic
Interventions: OTHER: Physical exercise|OTHER: Physical exercise and computerized cognitive training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity Study of GlaxoSmithKline (GSK) Biologicals' 10-valent Pneumococcal Conjugate Vaccine.
Status: COMPLETED
Conditions: Infections, Streptococcal
Interventions: BIOLOGICAL: Pneumococcal (vaccine)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Phase 1 Safety, Tolerability and Pharmacokinetics (PK) Study of FP-025 in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: FP-025|DRUG: Placebo|DRUG: FP-025|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Research Study To Test How Multiple Doses Of Filgrastim Hospira Works In The Body Of Healthy Study Subjects When Given by Subcutaneous Injection (SC) (Shot) Compared To An Already U.S.-Approved Drug Neupogen® (Amgen)
Status: COMPLETED
Conditions: Neutropenia (Low White Blood Cell Count)
Interventions: BIOLOGICAL: Filgrastim Hospira (US)|BIOLOGICAL: U.S.-approved Neupogen®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of Ridaforolimus in Pediatric Participants With Advanced Solid Tumors (MK-8669-056)
Status: TERMINATED
Conditions: Solid Tumors
Interventions: DRUG: Ridaforolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Inetetamab + Pyrotinib + Chemotherapy in Previously Untreated HER2-Positive Metastatic Breast Cancer
Status: NOT_YET_RECRUITING
Conditions: HER2-positive Recurrent/Metastatic Breast Cancer
Interventions: DRUG: Inetetamab, pyrotinib, chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Segment Transport Versus Acute Shortening In The Treatment of Tibial Pseudarthroses With Bone Loss
Status: COMPLETED
Conditions: TIBIA PSEUDOARTHROSES
Interventions: OTHER: ASR METHOD
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Use of CoreBone Coral Particles vs. Cones for Preservation of Alveolar Bone
Status: UNKNOWN
Conditions: Bone Loss
Interventions: DEVICE: CoreBone Cone device|DEVICE: CoreBone 500 device
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Home Blood Pressure Variability and Its Link to Arteriosclerosis and Metabolic Dysfunction in Hypertensive Patients
Status: RECRUITING
Conditions: Hypertension|Blood Pressure Monitoring, Home|Arteriosclerosis|Metabolic Syndrome X
Interventions: BEHAVIORAL: Healthscan App
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Umbrella Review and Updated Systematic Review and Meta-analysis of Pulses/Legumes and Incident Cardiometabolic Diseases
Status: UNKNOWN
Conditions: Cardiovascular Diseases|Coronary Heart Disease|Stroke|Diabetes Mellitus, Type 2|Hypertension|Obesity
Interventions: OTHER: Dietary pulses or legumes
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study to Evaluate the Efficacy of MONotherapy of TiviCAY® Versus a Triple Therapy in HIV-1-infected Patients
Status: TERMINATED
Conditions: HIV
Interventions: DRUG: dolutegravir 50mg +abacavir 600mg +lamivudine 300mg|DRUG: dolutegravir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Helicobacter Eradication Relief of Dyspeptic Symptoms
Status: COMPLETED
Conditions: Functional Dyspepsia
Interventions: DRUG: Amoxicillin, Clarythromycin, Omeprazole for ten days
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Combined SAD and MAD Study to Investigate the Safety, Tolerability and Pharmacokinetic Profile of IFB-088
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: IFB-088 (2.5-60.0mg) oral capsule|DRUG: Placebo (2.5-60.mg) oral capsule|DRUG: IFB-088 (15.0-50.0mg) oral capsule|DRUG: Placebo oral (15.0-50.0mg) capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Gender Specific Differences in Postoperative Sore Throat for Ambu® AuraGain™ Laryngeal Mask
Status: COMPLETED
Conditions: Postoperative Complications|Postoperative Pain
Interventions: DEVICE: Ambu® AuraGain™ Laryngeal Mask (LM)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Localizing the Epileptogenic Zone With High Resolution Electroencephalography
Status: COMPLETED
Conditions: Partial Epilepsy
Interventions: DEVICE: High Resolution EEG|DEVICE: Stereo-electroencephalography
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Lung Function and Patient Preference With QVA149 vs. Tiotropium in COPD Patients
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease|COPD
Interventions: DRUG: QVA149|DRUG: Tiotropium
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stopping Cognitive Decline and Dementia by Fighting Covert Cerebral Small Vessel Disease
Status: RECRUITING
Conditions: Cerebral Small Vessel Diseases|Stroke|Dementia
Interventions: PROCEDURE: Retinal Imaging|GENETIC: Blood sample|PROCEDURE: Evaluation of cardiovascular risks|PROCEDURE: Brain imaging (MRI)|OTHER: Cognitive Tests|OTHER: Geriatric Depression Scale (GDS)|OTHER: Instrumental Activities of Daily Living (IADL)|DIAGNOSTIC_TEST: Unipodal standing test|OTHER: Walking speed measurement
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: In Vivo Kinematics Comparison of Stryker or Zimmer Total Knee Arthroplasty
Status: COMPLETED
Conditions: Knee Prosthesis
Interventions: DEVICE: Stryker posterior cruciat retaining (PCR) total knee arthroplasty (TKA)|DEVICE: Zimmer PCR TKA
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy of Thrice Weekly Directly Observed Treatment, Short-course (DOTS) in HIV-associated Tuberculosis
Status: COMPLETED
Conditions: HIV Infections|Acquired Immunodeficiency Syndrome|Tuberculosis
Interventions: DRUG: INH, Rifampicin, Ethambutol and Pyrazinamide|DRUG: INH, Rifampicin, Ethambutol and Pyrazinamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preoperative Optimisation of Modifiable Risk Factors in Surgery of the Pancreas
Status: NOT_YET_RECRUITING
Conditions: Prehabilitation|Pancreas Cancer|Surgery|Postoperative Complications
Interventions: BEHAVIORAL: Preoperative optimisation program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Efficacy of Chlorella Supplementation on Health and Performance Following a 12-week Training Programme
Status: COMPLETED
Conditions: Sedentary|Overweight
Interventions: DIETARY_SUPPLEMENT: Chlorella supplementation|OTHER: 12 week cardiovascular training programme|DIETARY_SUPPLEMENT: Placebo Supplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Personalized Persistent Atrial Fibrillation Ablation: The PeAF-by-LAWT Trial
Status: RECRUITING
Conditions: Persistent Atrial Fibrillation|Persistent Atrial Fibrillation Longstanding
Interventions: PROCEDURE: Atrial Fibrillation transcatheter ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Extremely Low Frequency Electromagnetic Field Device Improving Sleep and Stress
Status: UNKNOWN
Conditions: Stress|Sleep Quality|Fatigue|Extremely Low Frequency Electromagnetic Field Device|Schumann Resonance
Interventions: DEVICE: Extremely low frequency electromagnetic field device|DEVICE: electromagnetic field with no wave
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Efficacy and Safety of Tocilizumab in Combination With DMARDs in Patients With Moderate to Severe Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: tocilizumab|DRUG: DMARDs|DRUG: Placebo|DRUG: DMARDs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The WATS3D (Wide Area Transepithelial Sample Biopsy With 3-Dimensional Computer-Assisted Analysis) U.S. Registry
Status: TERMINATED
Conditions: Barrett Esophagus|Gastroesophageal Reflux|Esophageal Dysplasia|Esophageal Diseases
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Simplified Meal Approach Using Hybrid Closed-loop Insulin Delivery in Youth and Young Adults With Type 1 Diabetes
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: DEVICE: SMA bolus option|DEVICE: Exactly estimated carbohydrate content bolus option
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ziv-aflibercept in Treating Patients With Locally Advanced, Unresectable, or Metastatic Gynecologic Soft Tissue Sarcoma
Status: COMPLETED
Conditions: Fallopian Tube Cancer|Female Reproductive Cancer|Ovarian Carcinosarcoma|Ovarian Sarcoma|Recurrent Ovarian Epithelial Cancer|Recurrent Uterine Sarcoma|Stage III Ovarian Epithelial Cancer|Stage III Uterine Sarcoma|Stage IV Ovarian Epithelial Cancer|Stage IV Uterine Sarcoma|Uterine Carcinosarcoma|Uterine Leiomyosarcoma
Interventions: DRUG: ziv-aflibercept
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Delayed Umbilical Cord Clamping Versus Cord Milking in Preterm Neonate
Status: TERMINATED
Conditions: Premature Birth
Interventions: PROCEDURE: Delayed cord clamping|PROCEDURE: Milking of the cord
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Efficacy and Safety Evaluation Study of Neuramis® Deep Lidocaine in Correction of Nasolabial Fold
Status: COMPLETED
Conditions: Nasolabial Fold
Interventions: DEVICE: Neuramis® Deep Lidocaine|DEVICE: Restylane® PERLANE-L
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Mobile Health Application Based on Omaha System on Symptoms and Quality of Life in COVID-19 Patients
Status: COMPLETED
Conditions: COVID-19|Symptoms and Signs|Quality of Life
Interventions: OTHER: COVOS app|OTHER: Standard Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Immunogenicity Study of the Hepatitis B Vaccine, HEPLISAV™, Compared to Engerix-B® Vaccine
Status: COMPLETED
Conditions: Healthy
Interventions: BIOLOGICAL: HEPLISAV|BIOLOGICAL: Engerix-B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Acetylcysteine Against Acute Renal Insult During Cardiopulmonary Bypass.
Status: SUSPENDED
Conditions: Cardiovascular Disease|Renal Insufficiency, Acute|Cardiopulmonary Bypass
Interventions: DRUG: N-Acetylcysteine 600mg/tab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Posturing-Adherence in Patients After Intraocular Surgery
Status: COMPLETED
Conditions: Retina; Lesion|Adherence
Interventions: DEVICE: Positioning measurement|DEVICE: Patient feedback|PROCEDURE: Usefulness of a sketch|DEVICE: Closure rate of macular holes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of Lumber Regression Technique on Disc Bulge Randomized Control Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Disc Disease
Interventions: COMBINATION_PRODUCT: Advanced Physiotherapy|OTHER: Conventional Physiotherapy Techniques
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Pembrolizumab and Nab Paclitaxel in Patients With Metastatic Urothelial Carcinoma
Status: COMPLETED
Conditions: Metastatic Urothelial Carcinoma
Interventions: DRUG: Pembrolizumab and Nanoparticle Albumin-bound Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of EPA in Men With Biochemical Recurrence or Progression of Prostate Cancer.
Status: RECRUITING
Conditions: Prostate Cancer
Interventions: COMBINATION_PRODUCT: MAG-EPA|DIETARY_SUPPLEMENT: Placebo group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Vinegar Consumption on Visceral Fat and Blood Glucose Concentration
Status: COMPLETED
Conditions: Visceral Obesity|Tooth Erosion|Insulin Resistance
Interventions: DIETARY_SUPPLEMENT: liquid vinegar|DIETARY_SUPPLEMENT: vinegar pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Clinical Investigation to Evaluate the Hemanext® Red Blood Cell Processing System for Extended Storage of Leukoreduced Red Blood Cells
Status: WITHDRAWN
Conditions: Whole Blood Donations and Leukoreduction
Interventions: DEVICE: Hemanext One
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Efficacy and Safety of CDP870 Versus Placebo in the Treatment of the Signs and Symptoms of Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: CDP870
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized Trial Assessing the Effects of Inclisiran on Clinical Outcomes Among People With Cardiovascular Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Atherosclerotic Cardiovascular Disease
Interventions: DRUG: Inclisiran|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Electro-acupuncture for Abdominal Obesity: Study for a Randomized Controlled Trial
Status: COMPLETED
Conditions: Obesity, Abdominal
Interventions: DEVICE: Electro-acupuncture|DEVICE: Sham electro-acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Study of Melphalan in Pediatric Hematopoietic Stem Cell Transplantation
Status: RECRUITING
Conditions: Hematopoietic Stem Cell Transplantation
Interventions: DRUG: Melphalan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nebivolol Effect on Nitric Oxide Levels, Blood Pressure, and Renal Function in Kidney Transplant Patients
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Nebivolol|DRUG: Metoprolol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Collateral-based reSetting of Endovascular Treatment Time Window for Stroke (CoSETS)
Status: TERMINATED
Conditions: Acute Ischemic Stroke
Interventions: PROCEDURE: endovascular thrombectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MIO-CPP to Improve the Well-being, Permanency, and Safety Outcomes for Young Children at Risk of or in Out-of-home Placement in Philadelphia and Bucks Counties, and Affected by Maternal Substance Use
Status: ENROLLING_BY_INVITATION
Conditions: Substance Use Disorders|Parent-Child Relations|Parent Child Abuse
Interventions: BEHAVIORAL: MIO-CPP|BEHAVIORAL: MIO-CPP-CRS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Irritation Study With New Calcipotriol Ointment Formulations in Healthy Subjects
Status: COMPLETED
Conditions: Irritation
Interventions: DRUG: Six different calcipotriol ointment formulations, and two currently marketed topical vitamin D analogues.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose:
Clinical trial: A Dose Escalation Study of Tenofovir Alafenamide in Treatment-Naive Patients
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Tenofovir DF|DRUG: Tenofovir alafenamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: L-Arginine and Spironolactone Trial in Dialysis-Dependent ESRD
Status: WITHDRAWN
Conditions: End Stage Renal Disease|Hemodialysis
Interventions: DRUG: Spironolactone|DIETARY_SUPPLEMENT: L-arginine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Role of Prophylactic Antibiotics in Preventing Pelvic Infection After Surgical Evacuation
Status: UNKNOWN
Conditions: Antibiotics Causing Adverse Effects in Therapeutic Use
Interventions: DRUG: Group 1: Antibiotic receiving group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: BTX-A51 in Patients with Liposarcoma
Status: RECRUITING
Conditions: Liposarcoma|Recurrent Liposarcoma|Metastatic Liposarcoma|Unresectable Liposarcoma|MDM2 Gene Amplification
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: AdvanTIG-202: Anti-PD-1 Monoclonal Antibody Tislelizumab (BGB-A317) Combined With or Without Anti-TIGIT Monoclonal Antibody Ociperlimab (BGB-A1217) in Participants With Previously Treated Recurrent or Metastatic Cervical Cancer
Status: COMPLETED
Conditions: Cervical Cancer
Interventions: DRUG: Tislelizumab|DRUG: Ociperlimab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Management of OAB in Female Patients .
Status: COMPLETED
Conditions: Overactive Bladder
Interventions: DRUG: Solfenacin|DRUG: Mirabegron|DRUG: Tadalafil 5mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Non Invasive Methods for Differential Diagnosis Radionecrosis/Recurrence After Radiosurgery of Brain Metastases
Status: COMPLETED
Conditions: Brain Metastases|Growing Lesions After Radiosurgical Treatment
Interventions: OTHER: imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Early Transcranial Doppler Goal Directed Therapy After Cardiac Arrest: a Pilot Study
Status: UNKNOWN
Conditions: Cardiac Arrest|Cerebral Lesion|Ischemic Encephalopathy|Ischemic Reperfusion Injury
Interventions: OTHER: MAP increased to optimize cerebral blood flow|OTHER: MAP between 65 and 85 mmHg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of EUS-Guided 22 Gauge Core Biopsy Versus Fine-needle Aspiration for Suspected Pancreatic Neoplasms
Status: COMPLETED
Conditions: Pancreatic Tumor
Interventions: DEVICE: Fine Needle Aspiration (FNA) and Core biopsy (FNB)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Assessment of Different Protocols for Cervical Dentin Hypersensitivity Treatment
Status: COMPLETED
Conditions: Hypersensitivity Dentin|Dentin Sensitivity|Dentin Hypersensitivity|Dentine Hypersensitivity
Interventions: DRUG: Resin modified glass ionomer|DRUG: Potassium Nitrate 2%|PROCEDURE: Low level laser therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of a Multi-faceted Intervention Combining an Educational Outreach Visit to General Practitioners and Patient Education Material to Deprescribe Proton Pump Inhibitors (PPI): a Population-based, Pragmatic, Cluster-randomized Controlled Trial
Status: COMPLETED
Conditions: Proton Pump Inhibitors|Deprescription
Interventions: OTHER: GP will receive the educational outreach visit by a DAM (healthcare representative).|OTHER: Patient education material on PPI deprescribing will be sent to the patients
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Interventions in Mathematics and Cognitive Skills
Status: RECRUITING
Conditions: Math Learning Disability|Child Development|Developmental Disability|Learning Disabilities|Learning Disabled|Learning Curve|Mathematics Disorder|Dyscalculia|Dyscalculia, Primary|Dyscalculia, Acquired|Specific Learning Disorder, With Impairment in Mathematics|Individuality|Behavior, Child|Behavior and Behavior Mechanisms|Behavior|Decision Making|Neuronal Plasticity|Cognition|Cognition Disorder|Cognitive Dysfunction|Cognitive Change|Cognitive Impairment, Mild|Cognitive Developmental Delay|Cognitive Orientation|Cognitive Delay, Mild|Cognitive Deficits, Mild|Cognitive Abnormality|Neuroscience
Interventions: OTHER: Interventions in Mathematics and Cognitive Skills - Experimental|OTHER: Interventions in Mathematics and Cognitive Skills - Active Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Lebrikizumab in Participants With Persistent Moderate to Severe Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: Lebrikizumab|DRUG: Placebo|DRUG: TCS Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Efficacy and Safety of Deucravacitinib in Participants With Active Discoid and/or Subacute Cutaneous Lupus Erythematosus (DLE/SCLE)
Status: ACTIVE_NOT_RECRUITING
Conditions: Lupus Erythematosus, Discoid|Lupus Erythematosus, Subacute Cutaneous
Interventions: DRUG: Deucravacitinib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of HR071603(Ketamine Nasal Spray) in Healthy Subjects
Status: COMPLETED
Conditions: Depression
Interventions: DRUG: HR071603|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cognitive Behavior Therapy for Social Media Addiction, Insomnia, and Family Relationship Among Individuals With Social Media Addiction: A Randomized Control Tria
Status: ACTIVE_NOT_RECRUITING
Conditions: Cognitive Behavior Therapy for Social Media Addiction
Interventions: BEHAVIORAL: Cognitive behavioral therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Thoracentesis: Symptoms and Prediction of the Need for Therapeutic Thoracentesis
Status: COMPLETED
Conditions: Pleural Effusion|Dyspnea|Patient Reported Outcomes|Diaphragm Movement|Ultrasound
Interventions: OTHER: Assesment of diaphragm shape and diaphragm movement (by M-mode and the AREA-method) by ultrasound before and after thoracentesis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Trial of TRX518 (Anti-GITR mAb) in Stage III or IV Malignant Melanoma or Other Solid Tumors
Status: COMPLETED
Conditions: Unresectable Stage III or Stage IV Malignant Melanoma or Other Solid Tumor Malignancies
Interventions: BIOLOGICAL: TRX518
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial on the Efficacy of Tegaderm Chlorhexidine Gluconate (CHG) in Reducing Catheter Related Bloodstream Infections
Status: UNKNOWN
Conditions: Catheterization|Infection
Interventions: DEVICE: Transparent adhesive dressing with an integrated gel pad containing 2% w/w chlorhexidine gluconate (CHG) (TegaDerm CHG)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The CLiFF Study: Change in Liver Function and Fat in Pre-operative Chemotherapy for Colorectal Liver Metastases
Status: UNKNOWN
Conditions: Colorectal Cancer|Liver Metastasis Colon Cancer|Chemotherapy Effect|Obesity
Interventions: DIAGNOSTIC_TEST: MR|DIAGNOSTIC_TEST: LiMAx
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Examination of a New Irrigation System for Transanal Irrigation in Children With Fecal Incontinence
Status: COMPLETED
Conditions: Fecal Incontinence|Constipation - Functional
Interventions: DEVICE: Cone Small, Qufora A/S|DEVICE: Colotip, Coloplast A/S
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Learn How Different Amounts of PF-06954522 Are Tolerated and Act in Adults With Type 2 Diabetes Mellitus
Status: RECRUITING
Conditions: Type 2 Diabetes Mellitus (T2DM)|Obesity
Interventions: DRUG: Placebo|DRUG: Rosuvastatin|DRUG: Midazolam|DRUG: Omeprazole|DRUG: PF-06954522
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Hepatic Arterial Infusion Plus Chemotherapy in Treating Patients With Colorectal Cancer Metastatic to the Liver
Status: COMPLETED
Conditions: Adenocarcinoma of the Colon|Adenocarcinoma of the Rectum|Liver Metastases|Recurrent Colon Cancer|Recurrent Rectal Cancer|Stage IV Colon Cancer|Stage IV Rectal Cancer
Interventions: DRUG: floxuridine|DRUG: dexamethasone|DRUG: oxaliplatin|DRUG: capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Acceptance and Commitment Therapy in Patients With Chronic Renal Failure
Status: ACTIVE_NOT_RECRUITING
Conditions: Kidney Failure, Chronic
Interventions: BEHAVIORAL: psychoeducation based on acceptance and commitment therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Using Aromatherapy in Substance Use Disorder
Status: COMPLETED
Conditions: Substance Use Disorders
Interventions: OTHER: Aroma Inhaler with Bergamot essential oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Autologous BMA Vs Saline and LAM + LP-PRP Vs Saline Evaluations in Knee OA
Status: NOT_YET_RECRUITING
Conditions: Osteoarthritis, Knee
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: GlaucoT Glaucoma Treatment Glasses in the Treatment of Primary Open-Angle Glaucoma
Status: SUSPENDED
Conditions: Primary Open-Angle Glaucoma
Interventions: DEVICE: GlaucoT Glaucoma Treatment Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Impact of Early Intervention on Maternal Stress in Mothers of Fetuses Diagnosed With Single Ventricle Physiology
Status: COMPLETED
Conditions: Heart Defects, Congenital|Hypoplastic Left Heart Syndrome|Single Ventricle Defect|Stress, Psychological
Interventions: BEHAVIORAL: Early palliative care team consultation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Atomoxetine for Children With Acquired Attentional Disorders Following Completion of Chemotherapy for ALL
Status: TERMINATED
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: DRUG: Atomoxetine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study on The Efficacy and Safety of Berberine-containing Triple Therapy in Helicobacter Pylori First-Line Eradication
Status: COMPLETED
Conditions: Helicobacter Pylori Infection|Chronic Gastritis
Interventions: DRUG: Berberine|DRUG: Vonoprazan|DRUG: Amoxicillin|DRUG: Rabeprazole|DRUG: Bismuth|DRUG: Clarithromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Texting to Improve Adherence in HIV+ With Bipolar Disorder
Status: COMPLETED
Conditions: HIV Disease|Bipolar Disorder
Interventions: BEHAVIORAL: Psychoeducation|BEHAVIORAL: individualized Texting for Adherence Building (iTAB)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Trial of Three Stem Cell Mobilization Regimens for Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: bortezomib (Velcade)|DRUG: cyclophosphamide|DRUG: G-CSF|DRUG: Plerixafor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intracolonic FODMAP Infusion in Healthy Volunteers
Status: RECRUITING
Conditions: Irritable Bowel Syndrome
Interventions: DIETARY_SUPPLEMENT: Fermentable Oligo-, Di- Monosaccharides And Polyols (FODMAPs)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Efficacy of ABI-007 Plus Gemcitabine or sLV5FU2 as First-line Therapy in Patients With Metastatic Pancreatic Cancer
Status: UNKNOWN
Conditions: Metastatic Pancreatic Cancer
Interventions: DRUG: ABI-007|DRUG: Gemcitabine|DRUG: simplified LV5FU2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety and Efficacy Study of Tavilermide (MIM-D3) Ophthalmic Solution for the Treatment of Dry Eye Disease
Status: COMPLETED
Conditions: Keratoconjunctivitis Sicca
Interventions: DRUG: 1% Tavilermide Ophthalmic Solution|DRUG: Placebo Ophthalmic Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, Pharmacokinetic, and Pharmacodynamic Study in Healthy Male and Female Subjects and Safety, Tolerability, Pharmacokinetics, and Pilot Efficacy Biomarkers in Subjects With Cold Agglutinin Disease
Status: RECRUITING
Conditions: First in Man Study to Evaluate Initial Safety
Interventions: DRUG: GL-0719|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Interventions for HIV Negative Men and Women Who Have High-risk Suspected Exposure to HIV
Status: COMPLETED
Conditions: HIV Prevention|HIV Infections
Interventions: DRUG: tenofovir + emtricitabine, lopinavir/ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: AV-23-001 AVAVA MIRIA Pilot Study
Status: RECRUITING
Conditions: Wrinkle|Acne Scars - Mixed Atrophic and Hypertrophic|Pigmented Lesions|Skin Laxity|Scars
Interventions: DEVICE: MIRIA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Bilateral Infraorbital Block Versus Intranasal Bupivacaine in Transsphenoidal Pituitary Adenoma Resection
Status: UNKNOWN
Conditions: Intraoperative Hypertension
Interventions: PROCEDURE: infraorbital block|PROCEDURE: topical intranasal bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of Naoqingzhiming Tablets in Healthy Chinese Subjects
Status: UNKNOWN
Conditions: Healthy Volunteers
Interventions: DRUG: Naoqingzhiming Tablets (contains echinacoside 180mg)|DRUG: placebo of Naoqingzhiming Tablets (without echinacoside)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Home-based Pulmonary Rehabilitation and Health Coaching in Fibrotic Interstitial Lung Disease
Status: RECRUITING
Conditions: Fibrotic Interstitial Lung Disease
Interventions: BEHAVIORAL: Home-based pulmonary rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of Osseointegration Process of Dental Implants
Status: COMPLETED
Conditions: Dental Implant Failed|Osseointegration Failure of Dental Implant
Interventions: OTHER: Patients selection|OTHER: Implnat placement|OTHER: Recall visits
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Treatment of Insufficient Superficial and Perforating Veins of the Lower Limb Using HIFU
Status: COMPLETED
Conditions: Varicose Ulcer|Veins Diseases|Vein, Varicose
Interventions: DEVICE: ECHOPULSE
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Pilates on Biopsychosocial Characteristics in the Covid-19 Pandemic
Status: COMPLETED
Conditions: COVID-19|Healthy|Sedentary|Exercise|Pilates
Interventions: BEHAVIORAL: Sedantary|BEHAVIORAL: Exercise therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Weekly Versus Every Three Weeks of Carboplatin Plus Paclitaxel in Patients With Advanced Epithelial Ovarian Cancer
Status: COMPLETED
Conditions: Advanced Epithelial Ovarian Cancer
Interventions: DRUG: Carboplatin/paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Foreign Body Airway Obstruction Interventions Through Simulation
Status: NOT_YET_RECRUITING
Conditions: Choking|Airway Obstruction
Interventions: OTHER: Dechoker|OTHER: LifeVac|OTHER: Abdominal Thrusts
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Efficiency of Preoxygenation in Obese Patients: Pressure Assisted Versus Traditional Method
Status: COMPLETED
Conditions: Obesity
Interventions: PROCEDURE: Standard preoxygenation|PROCEDURE: BiPAP assisted preoxygenation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: High-Dose Steroid for Knee Arthroplasty Patients Expected to Have Postoperative Pain
Status: COMPLETED
Conditions: Postoperative Pain|Postoperative Nausea and Vomiting|Knee Osteoarthritis|Perioperative/Postoperative Complications|Surgery|Opioid Use|Catastrophizing Pain|Chronic Pain
Interventions: DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Lifestyle Medicine Practice
Status: COMPLETED
Conditions: Chronic Lifestyle Related Disease|Diabetes|Overweight and Obesity|Dyslipidemias|Hypertension|Cardiovascular Diseases
Interventions: BEHAVIORAL: Lifestyle Medicine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Sufentanil vs. Remifentanil in Total Intravenous Anesthesia With Remimazolam on Postoperative Pain
Status: RECRUITING
Conditions: Stomach Neoplasms
Interventions: DRUG: sufentanil-remimazolam group|DRUG: remifentanil-remimazolam group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Basel Stent Kosten Effektivitäts Trial Drug Eluting Balloons vs. Drug Eluting Stents in Small Vessel Interventions
Status: COMPLETED
Conditions: Coronary Heart Disease
Interventions: DEVICE: Drug eluting balloon|DEVICE: Drug eluting stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Onset of Action of Loratadine and Fexofenadine in Participants With Seasonal Allergic Rhinitis (P08712)
Status: COMPLETED
Conditions: Rhinitis
Interventions: DRUG: loratadine|DRUG: fexofenadine|DRUG: placebo to loratadine|DRUG: placebo to fexofenadine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Being Conducted at Multiple Locations to Compare Safety and Efficacy of Three Different Regimens; (1) High-Dose Lenalidomide; (2) Lenalidomide + Azacitidine; or (3) Azacitidine in Subjects ≥ 65 Years With Newly-Diagnosed Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Acute Myeloid Leukemia|Acute Myelogenous Leukemia
Interventions: DRUG: Azacitidine|DRUG: Lenalidomide|OTHER: Best Supportive Care (BSC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Analysis of a Virtual Reality Task in Patients With Duchenne Muscular Dystrophy
Status: COMPLETED
Conditions: Duchenne Muscular Dystrophy
Interventions: DEVICE: Acquisition on TouchScreen|DEVICE: Acquisition on Kinect|DEVICE: Acquisition on LeapMotion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: An Efficacy, Safety, Tolerability and Dose Finding Study of XXB750 in Resistant Hypertension Patients.
Status: ACTIVE_NOT_RECRUITING
Conditions: Resistant Hypertension
Interventions: BIOLOGICAL: Experimental drug|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT