pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: BRIGHT-SC: Blisibimod Response in IgA Nephropathy Following At-Home Treatment by Subcutaneous Administration
Status: COMPLETED
Conditions: IgA Nephropathy
Interventions: DRUG: Blisibimod|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Habit Formation for Adherence to Statin Use and LDL Reduction
Status: COMPLETED
Conditions: Medication Adherence
Interventions: BEHAVIORAL: Sweepstake Incentive 1|BEHAVIORAL: Sweepstake Incentive 2|BEHAVIORAL: Sweepstake Incentive 3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Does Topical Ophthalmic Proparacaine 0.5% Prior to Probing and Irrigation Decrease Pain?
Status: RECRUITING
Conditions: Epiphora|Dacryostenosis|Dacryocystitis
Interventions: DRUG: Proparacaine Hydrochloride ophthalmic solution, USP 0.5%|DRUG: Balanced salt solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Phase 3, Double-blind/Double-dummy, Safety/Efficacy/Superiority of Sibutramine/Topiramate XR in Adults With Overweight
Status: NOT_YET_RECRUITING
Conditions: Overweight|Obesity
Interventions: DRUG: ADF1 Group Eurofarma drug association of Sibutramine IR 15mg / Topiramate XR 75mg|DRUG: ADF2 Group Eurofarma drug association of Sibutramine IR 15mg / Topiramate XR 100mg|DRUG: SIB Group Sibus (Sibutramine) 15mg|DRUG: Placebo Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: rTMS on Mismatch Negativity of Schizophrenia
Status: UNKNOWN
Conditions: Schizophrenia|Mismatch Negativity
Interventions: DEVICE: Transcranial magnetic stimulation|DEVICE: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of New Formulations of GlaxoSmithKline Biologicals' DTPa-HBV-IPV/Hib Vaccine (GSK217744)
Status: COMPLETED
Conditions: Tetanus|Poliomyelitis|Hepatitis B|Haemophilus Influenzae Type b|Acellular Pertussis|Diphtheria
Interventions: BIOLOGICAL: Infanrix hexa™|BIOLOGICAL: Prevenar 13®|BIOLOGICAL: GSK217744
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Prospective Decision Impact Clinical Utility Trial of KidneyIntelX
Status: ACTIVE_NOT_RECRUITING
Conditions: Diabetic Kidney Disease|Chronic Kidney Diseases|Chronic Kidney Disease Stage 1|Chronic Kidney Disease Stage 2|Chronic Kidney Disease Stage 3
Interventions: DIAGNOSTIC_TEST: KidneyIntelX
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Feasibility of the Geriatric Activation Program Pellenberg With Caregiver Involvement
Status: COMPLETED
Conditions: Hip Fractures|Stroke|Frailty
Interventions: OTHER: GAPP+Care|OTHER: +Care|OTHER: Observation of GAPP+Care
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Adhering Flowable Composite With and Without Adhesive Vs Flowable in Cervical Lesions
Status: UNKNOWN
Conditions: Dental Restoration Failure
Interventions: OTHER: flowable resin composite|OTHER: self adhering flowable|OTHER: self adhering flowable with adhesive
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ceramic Modular Dual Mobility in Primary Total Hip Arthroplasty (THA)
Status: RECRUITING
Conditions: Coxarthrosis; Primary
Interventions: DEVICE: Dual Mobility Cup|DEVICE: Standard Acetabular component
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Cutaneous Metastases With Diphenylcyclopropenone (DPCP)
Status: COMPLETED
Conditions: Neoplasm Metastasis|Melanoma
Interventions: DRUG: Diphenylcyclopropenone (DPCP)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility of Exosome Analysis in Cerebrospinal Fluid During the Diagnostic Workup of Metastatic Meningitis (Exo-LCR)
Status: RECRUITING
Conditions: Breast Cancer
Interventions: PROCEDURE: Consultation|PROCEDURE: Cerebral and medullary MRI, lumbar puncture, CSF sampling|BIOLOGICAL: biological test
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Trial to Evaluate Efficacy of Magnetic Resonant Therapy (MRT) in PTSD
Status: COMPLETED
Conditions: Stress Disorders, Post-Traumatic
Interventions: DEVICE: Magnetic EEG/ECG-guided Resonance Therapy|DEVICE: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: An Observational LTFU Study for Patients Previously Treated With Autologous ex Vivo Gene Therapy for ADA-SCID
Status: ENROLLING_BY_INVITATION
Conditions: Adenosine Deaminase Deficiency|Severe Combined Immunodeficiency (SCID)
Interventions: BIOLOGICAL: autologous ex vivo gene therapy products based on the EFS LV encoding for the human adenosine deaminase (ADA) gene (EFS-ADA LV)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Chemotherapy Based on PET Scan in Treating Patients With Stage I or Stage II Hodgkin Lymphoma
Status: TERMINATED
Conditions: Lymphoma
Interventions: DRUG: Doxorubicin|DRUG: Bleomycin|DRUG: Vinblastine|DIAGNOSTIC_TEST: PET|RADIATION: INRT|DRUG: Dacarbazine|DRUG: Etoposide|DRUG: Cyclophosphamide|DRUG: Vincristine|DRUG: Procarbazine|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Combination of Pemetrexed and Irinotecan Every Two Weeks in Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: pemetrexed|DRUG: irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Nebulized Ampion for the Treatment of Adult COVID-19 Patients With Respiratory Distress
Status: COMPLETED
Conditions: Covid19
Interventions: BIOLOGICAL: Ampion|OTHER: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Self-efficacy Enhancement in a Virtual Reality Training for Fear of Heights
Status: ENROLLING_BY_INVITATION
Conditions: Fear of Heights|Specific Phobia, Situational
Interventions: BEHAVIORAL: Visual Feedback|BEHAVIORAL: Self-efficacy enhancement:|BEHAVIORAL: placebo intervention|BEHAVIORAL: No visual feedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Suvorexant and Alcohol
Status: RECRUITING
Conditions: Alcohol Use Disorder
Interventions: DRUG: Alcohol|DRUG: Placebo|DRUG: Suvorexant|DRUG: Suvorexant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of Trastuzumab Emtansine (T-DM1) Plus Pertuzumab/Pertuzumab Placebo Versus Trastuzumab [Herceptin] Plus a Taxane in Participants With Metastatic Breast Cancer (MARIANNE)
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: docetaxel|DRUG: paclitaxel|DRUG: pertuzumab|DRUG: pertuzumab-placebo|DRUG: trastuzumab [Herceptin]|DRUG: trastuzumab emtansine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Biomarker Signature and Musculoskeletal Ultrasound Profile in Rheumatoid Arthritis Patients
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: OTHER: Musculoskeletal Ultrasound Imaging|OTHER: Synovial biopsy|OTHER: Biological samples collection|OTHER: Questionnaires
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Evaluate the Efficacy and Safety of Reldesemtiv in Patients With Amyotrophic Lateral Sclerosis (ALS)
Status: TERMINATED
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DRUG: Reldesemtiv|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Improving Congenital Heart Disease Care
Status: NOT_YET_RECRUITING
Conditions: Congenital Heart Disease|Behavior, Health|Quality of Life|Empowerment, Patient|Activation, Patient
Interventions: BEHAVIORAL: Digital patient empowerment intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Dexmedetomidine for the Control of Post-Operative Pain in Thoracotomy Patients
Status: COMPLETED
Conditions: Post-operative Pain|Respiratory Depression
Interventions: DRUG: Dexmedetomidine|OTHER: Placebo (Normal Saline)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Controlled Trial of Comet Via the Internet or in Group Format.
Status: COMPLETED
Conditions: Oppositional Defiant Disorder|Attention Deficit Hyperactivity Disorder
Interventions: BEHAVIORAL: Comet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Dietary DHA Supplementation on Sperm Quality
Status: COMPLETED
Conditions: SPERM
Interventions: DIETARY_SUPPLEMENT: Sunflower oil|DIETARY_SUPPLEMENT: Docosahexanoic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: To Compare the Effectiveness of Suvorexant vs Placebo on Sleep Pressure in Hypertensives With Insomnia
Status: COMPLETED
Conditions: Hypertension|Insomnia
Interventions: DRUG: suvorexant|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of TQB2450 in Patients With Recurrent or Metastatic Squamous Cell Cancer of the Head and Neck（R/M SCCHN）
Status: UNKNOWN
Conditions: Squamous Cell Carcinoma of the Head and Neck
Interventions: DRUG: TQB2450+cisplatin or carboplatin + 5-Fluorouracil (5-FU)|DRUG: placebo+cisplatin or carboplatin + 5-Fluorouracil (5-FU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Nasal Symptom Relief and Side Effects in Hayfever Patients Treated With Aerius (Desloratadine)(P03442)
Status: COMPLETED
Conditions: Rhinitis, Allergic, Seasonal
Interventions: DRUG: desloratadine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase III Study of Idebenone in Duchenne Muscular Dystrophy (DMD)
Status: COMPLETED
Conditions: Muscular Dystrophy, Duchenne|Ambulatory Care
Interventions: DRUG: Placebo|DRUG: Idebenone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Virtual Reality Exposure Intervention on Social Physical Anxiety in Women With Obesity
Status: RECRUITING
Conditions: Obesity|Exercise|Virtual Reality
Interventions: BEHAVIORAL: Exposure intervention in virtual reality|BEHAVIORAL: Exercise|BEHAVIORAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Local Tolerability of Chitosan-N-acetylcysteine Eye Drops in Healthy Young Volunteers
Status: COMPLETED
Conditions: Dry Eye Syndromes
Interventions: DEVICE: 0.05% Chitosan-N-Acetylcysteine eye drops|DEVICE: 0.1% Chitosan-N-Acetylcysteine eye drops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of Novartis Meningococcal B Vaccine Formulated With OMV Manufactured at Two Different Sites, in Healthy Adolescents Aged 11-17 Years
Status: COMPLETED
Conditions: Meningococcal Disease|Meningococcal Meningitis
Interventions: BIOLOGICAL: Serogroup B meningococcal vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: An Extension Study to Provide Continued Bevacizumab Therapy to Participants With Solid Tumors Who Were Previously Enrolled in a Roche/Genentech Sponsored Study
Status: COMPLETED
Conditions: Neoplasms
Interventions: DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Immunogenicity and Safety of Two Formulations of GSK Biologicals' Human Rotavirus (HRV) Vaccine (444563), in Healthy Infants Starting at Age 6-12 Weeks
Status: COMPLETED
Conditions: Infections, Rotavirus|Rotavirus Vaccines
Interventions: BIOLOGICAL: HRV PCV-free liquid vaccine|BIOLOGICAL: Rotarix
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Quetiapine XR Versus Sertraline in Acute Bipolar Depression as add-on Therapy
Status: COMPLETED
Conditions: Bipolar Disorder|Bipolar Depression
Interventions: DRUG: Extended release quetiapine (quetiapine XR)|DRUG: Sertraline|DRUG: adequate mood stabilizer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Systemic and Topical Antivirals for Control of Cytomegalovirus Anterior Uveitis: Treatment Outcomes
Status: RECRUITING
Conditions: Cytomegalovirus Anterior Uveitis
Interventions: DRUG: Valganciclovir Hydrochloride|DRUG: Ganciclovir Sodium|DRUG: Placebo Oral Tablet|DRUG: Topical placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vaccine and Antibody Treatment of Prostate Cancer
Status: COMPLETED
Conditions: Prostatic Neoplasms
Interventions: BIOLOGICAL: PROSTVAC-V/TRICOM|BIOLOGICAL: PROSTVAC-F/TRICOM|DRUG: MDX-010|DRUG: Sargramostim
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Returning to Work. Efficacy of "Tailored Physical Activity or" "Chronic Pain Self-management Program" in Sicklisted Citizens With Chronic Musculoskeletal Pain
Status: COMPLETED
Conditions: Musculoskeletal Pain
Interventions: OTHER: Tailored Physical Activity|BEHAVIORAL: "Chronic Pain Self-management Programme"|BEHAVIORAL: Health counselling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Exploring the Modulatory Role of Sex Hormones Along the Neuromechanical Axis in Females
Status: COMPLETED
Conditions: Role of Sex Hormones Along the Neuromechanical Axis
Interventions: DEVICE: Transcranial Magnetic Stimulation Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects Of Gamma Aminobutyric Acid On The Progression Of New Onset Juvenile Type 1 Diabetes
Status: UNKNOWN
Conditions: Type 1 Diabetes
Interventions: DRUG: Gamma Aminobutyric Acid (GABA)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of SB-742457, Added to Donepezil for the Treatment of Mild-to-moderate Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: SB-742457 15mg|DRUG: SB-742457 35mg|DRUG: Placebo|DRUG: donepezil 5-10mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Early Postoperative Drinking Water on Postoperative Recovery Quality of Patients With Thyroid Surgery
Status: UNKNOWN
Conditions: Thyroid Tumor
Interventions: BEHAVIORAL: Early resumption of oral intake|BEHAVIORAL: Late resumption of oral intake
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Combination Chemotherapy With or Without Radiation Therapy in Treating Patients With Hodgkin's Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Lymphoma
Interventions: BIOLOGICAL: bleomycin sulfate|DRUG: ABVD regimen|DRUG: BEACOPP regimen|DRUG: epirubicin hydrochloride|DRUG: prednisone|DRUG: vinblastine sulfate|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Efficacy of Dexamethasone - Ondansetron Versus Dexamethasone - Haloperidol in Reducing PONV
Status: COMPLETED
Conditions: Laparoscopic Cholecystectomy
Interventions: DRUG: Ondansetron|DRUG: Haloperidol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Complete Twelve Month Bone Remodeling With a Bi-phasic Injectable Bone Substitute in Benign Bone Tumors
Status: COMPLETED
Conditions: Bone Cyst
Interventions: DEVICE: CERAMENT™ |BONE VOID FILLER
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigation of the Performance and Safety of New 1-piece Open Ostomy Appliances Compared to Standard Care
Status: COMPLETED
Conditions: Ileostomy - Stoma
Interventions: DEVICE: Coloplast Test product 1|DEVICE: Coloplast Test product 2|DEVICE: Standard Care (Coloplast SenSura; Dansac Nova 1; Hollister Moderma FLex; Convatec Esteem; B.Braun Flexima Active)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Phase I/II Trial of Rhenium 188-P2045 in Small Cell Lung Cancer and Other Advanced Neuroendocrine Carcinomas
Status: WITHDRAWN
Conditions: Small Cell Lung Cancer (SCLC)|Neuroendocrine (NE) Tumors|Large Cell Neuroendocrine (NE) Tumors
Interventions: DRUG: Rhenium Re 188-P2045
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Prebiotic or Probiotic Supplements on Symptoms of Functional Constipation
Status: COMPLETED
Conditions: Constipation
Interventions: DIETARY_SUPPLEMENT: Prebiotics or Probiotics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Examine the, Safety, Tolerability and Pharmacokinetics Co-Administered Baclofen and Memantine in Obese and Lean, Otherwise Healthy Adults
Status: COMPLETED
Conditions: Healthy Volunteers;|Obese, Otherwise Healthy Volunteers
Interventions: DRUG: Baclofen|DRUG: Memantine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose:
Clinical trial: Health Assessment Study (0954-946)
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: MK0954, /Duration of Treatment : 16 Weeks|DRUG: Comparator : atenolol /Duration of Treatment : 16 Weeks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Trial of the LSD1 Inhibitor SP-2577 (Seclidemstat) in Patients With Advanced Solid Tumors
Status: COMPLETED
Conditions: Advanced Solid Tumors
Interventions: DRUG: SP-2577 Seclidemstat
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neural Basis of Language Processing
Status: COMPLETED
Conditions: Oligoastrocytoma|Astrocytoma|Oligodendroglioma
Interventions: DEVICE: fMRI|PROCEDURE: tractography|OTHER: neuropsychological examination
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Comparing the Effectiveness of Two Dietary Interventions for Fecal Incontinence
Status: COMPLETED
Conditions: Fecal Incontinence
Interventions: OTHER: low fodmap diet|DIETARY_SUPPLEMENT: Psyllium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Targeting Pediatric Brain Tumors With Sodium Glucose Cotransporter 2 Inhibitors (SGLT2i)
Status: RECRUITING
Conditions: Pediatric Brain Tumor
Interventions: DRUG: Dapagliflozin|DRUG: Carmustine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Total Blood Volume Measurement During Dialysis on the Incidence of Intradialytic Hypotension
Status: COMPLETED
Conditions: Hemodialysis Complication|Hypotension During Dialysis|Diagnostic Tests
Interventions: DIAGNOSTIC_TEST: adjustment of dry weight based on absolute blood volume measurement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: An Efficacy and Safety Study of SRM003 in the Treatment of Subjects Undergoing Placement of an Arteriovenous Graft to Facilitate Hemodialysis Access
Status: TERMINATED
Conditions: Arteriovenous Graft
Interventions: BIOLOGICAL: SRM003|OTHER: Participating Site's standard practice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Trial of All-trans Retinoic Acid (ATRA) in Advanced Adenoid Cystic Carcinoma
Status: COMPLETED
Conditions: Adenoid Cystic Carcinoma
Interventions: DRUG: Tretinoin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immersive Virtual Reality Exergames and Office Workers' Cardiometabolic Health
Status: NOT_YET_RECRUITING
Conditions: Exergaming|Metabolic Syndrome
Interventions: BEHAVIORAL: 12-week at-home immersive virtual reality exergame
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: AT-001 for Long-term Preservation of Brain Health in Aging
Status: COMPLETED
Conditions: Oxidative Stress
Interventions: DIETARY_SUPPLEMENT: AT-001|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Outcomes of the Use of Sodium Bicarbonate (8.4%) Solution as a Catheter Lock Solution to Prevent Hemodialysis Catheter Loss Due to Lumen Clot Formation
Status: COMPLETED
Conditions: End Stage Renal Disease|Acute Renal Failure|Hemodialysis Catheter Infection|Hemodialysis Complication|Hemodialysis Access Failure|Hemodialysis Catheter-Associated Bacteremia
Interventions: DRUG: Sodium Bicarbonate Catheter Lock Solution|DRUG: Normal Saline Catheter Lock Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Fertility Preservation Using Tamoxifen and Letrozole in Estrogen Sensitive Tumors Trial
Status: RECRUITING
Conditions: Infertility
Interventions: DRUG: Tamoxifen|DRUG: Letrozole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reduced Fluence Visudyne-Anti-VEGF-Dexamethasone In Combination for AMD Lesions (RADICAL)
Status: COMPLETED
Conditions: Choroidal Neovascularization|Macular Degeneration
Interventions: DRUG: verteporfin|DRUG: verteporfin|DRUG: ranibizumab|DRUG: dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Young Women's CoOp Study
Status: COMPLETED
Conditions: HIV|Sexual Risk|Sexually Transmitted Diseases|Substance Abuse|Violence|Victimization
Interventions: BEHAVIORAL: Young Women's CoOp|BEHAVIORAL: Staying Healthy and Eating Well
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Neoadjuvant Toripalimab in Combination With Gemcitabine and Cisplatin Therapy in Local Advanced Bladder Cancer Subjects
Status: RECRUITING
Conditions: Urinary Bladder Cancer
Interventions: DRUG: Neoadjuvant Toripalimab in Combination With Gemcitabine and Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Lee Silverman Voice Treatment BIG on Dynamic Balance in Parkinson's Patients
Status: COMPLETED
Conditions: Parkinson Disease|Motor Disorders|Balance; Distorted
Interventions: OTHER: Lee Silverman Voice Treatment BIG|OTHER: conventional treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Savings Intervention to Reduce Men's Engagement in HIV Risk Behaviors
Status: ACTIVE_NOT_RECRUITING
Conditions: Human Immunodeficiency Virus|STI|Alcohol Consumption|Incentives|Behavior
Interventions: BEHAVIORAL: Receives mobile banking account with incentives to save
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Matching Assessment and Treatment for Children With Disruptive Behaviour and Their Parents
Status: RECRUITING
Conditions: Disruptive Behavior Disorder|Emotional Disorder|Behavioural Disorder|Attention Deficit Hyperactivity Disorder|Conduct Disorder|Oppositional Defiant Disorder
Interventions: BEHAVIORAL: Behavioral Parent Training
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: DOnor Milk to REpair the Full-term Infant MIcrobiome in Infants Born Via Cesarean Section.
Status: NOT_YET_RECRUITING
Conditions: Microbial Colonization
Interventions: OTHER: Donor Human Milk - Nutritional Replacement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Stapled Transanal Rectal Resection (STARR) Surgery in Refractory Constipation Associated With Obstructive Defecation Syndrome (ODS)
Status: COMPLETED
Conditions: Obstructive Defecation Syndrome|Chronic Constipation|Rectocele|Intussusception
Interventions: PROCEDURE: Stapled Transanal Resection (STARR) with Transtar (PROXIMATE®) 33 mm Circular Stapler
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Polyphenols, Exercise, and Metabolomics
Status: COMPLETED
Conditions: Exercise-induced Inflammation|Exercise-induced Oxidative Stress|Exercise-induced Immune Dysfunction
Interventions: DIETARY_SUPPLEMENT: Nutrasorb|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Long-term Safety Study of Fluticasone Furoate (FF)/GW642444 and FF in Japanese Subjects With Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Fluticasone Furoate/GW642444 Inhalation Powder|DRUG: Fluticasone Furoate Inhalation Powder
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A First-in-human Study of YN001 in Healthy Volunteers
Status: RECRUITING
Conditions: Cardiovascular Diseases
Interventions: DRUG: YN001|DRUG: Placebo for YN001
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Utility of Adjusting Chemotherapy Dose & Dosing Schedule With the SALVage Weekly Dose-dense Regimen in Patients With Poor Prognostic OVARian Cancers Based on the Tumor Unfavorable Primary Chemosensitivity and Incomplete Debulking Surgery
Status: RECRUITING
Conditions: Ovarian Cancer
Interventions: DRUG: Carboplatin|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomised Controlled Trial of Mechanistic Effects of Rifaximin in Cirrhosis and Chronic Hepatic Encephalopathy
Status: COMPLETED
Conditions: Liver Cirrhosis|Hepatoencephalopathy, Early Fatal Progressive
Interventions: DRUG: Rifaximin-α|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Phase 2 Study to Evaluate Pharmacodynamics of YKP10811 in Patients With Chronic or Functional Constipation
Status: COMPLETED
Conditions: Chronic Constipation|Functional Constipation
Interventions: DRUG: Placebo Capsule|DRUG: YKP10811 Drug Product Capsule|DRUG: YKP10811 Drug Product Capsule|DRUG: YKP10811 Drug Product Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Diagnostic Study of Tumor Characteristics in Patients With Ewing's Sarcoma
Status: COMPLETED
Conditions: Localized Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor|Metastatic Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor|Recurrent Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor
Interventions: OTHER: laboratory biomarker analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Randomized Control Trial, Cryoablation as an Adjunct to Surgical Stabilization of Rib Fractures
Status: RECRUITING
Conditions: Pain, Postoperative|Rib Fracture Multiple
Interventions: DEVICE: Cryoablation of Intercostal Nerves|PROCEDURE: Standard surgical treatment of patients with multiple rib fractures
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Fluid Balance Neutralization During CRRT (Continuous Renal Replacement Therapy)
Status: COMPLETED
Conditions: Fluid Overload
Interventions: PROCEDURE: Increased net ultrafiltration with advanced hemodynamic monitoring|PROCEDURE: Zero or near-zero net ultrafiltration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Community Intervention to Prevent Nipah Spillover
Status: UNKNOWN
Conditions: Human NiV Infection
Interventions: BEHAVIORAL: Ask people not to drink raw sap|BEHAVIORAL: Ask people not to drink sap or drink sap from skirt protected trees|OTHER: No Intervention|OTHER: No Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Mean Arterial Pressure After Out-of-hospital Cardiac Arrest
Status: NOT_YET_RECRUITING
Conditions: Cardiac Arrest
Interventions: PROCEDURE: Maintain MAP ≥ 90 mmHg|PROCEDURE: Maintain MAP ≥ 65 mmHg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Pharmacokinetics/Pharmacodynamics and Safety/Tolerability of IN-C005 in Healthy Male Subjects
Status: UNKNOWN
Conditions: Healthy
Interventions: DRUG: IN-C005 dose A|DRUG: IN-C005 dose B|DRUG: IN-C005 dose C|DRUG: IN-C005 dose D|DRUG: IN-C005 dose E|DRUG: IN-C005 dose F
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Monitoring of Bone Free Flaps With Microdialysis
Status: COMPLETED
Conditions: Microsurgery|Head and Neck Reconstructive Surgery|Head and Neck Cancer|Head and/or Neck Shotgun Trauma|Bone Free Flap
Interventions: DEVICE: CMA 70 catheter directly positioned in bone tissue
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Oral Dietary Fucoxanthin Rich Supplement for Liver Health
Status: UNKNOWN
Conditions: Non Alcoholic Fatty Liver
Interventions: DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: FucoVital
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pharmacokinetic and Pharmacodynamic Study in Healthy Subjects Comparing the Interactions Between E5501 and Verapamil and Cyclosporine.
Status: COMPLETED
Conditions: Idiopathic Thrombocytopenic Purpura (ITP)
Interventions: DRUG: E5501
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Extracorporeal Shock Wave Therapy on Spastic Equinus Foot in Stroke Patients
Status: RECRUITING
Conditions: Stroke|Equinus Deformity|Spasticity, Muscle
Interventions: DEVICE: fESWT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tranexamic Acid Versus Placebo to Reduce Perioperative Bleeding After Major Hepatectomy
Status: TERMINATED
Conditions: Blood Loss, Surgical
Interventions: DRUG: acid tranexamic|DRUG: Nacl 0.9%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Oxaliplatin, Capecitabine, and Radiation Therapy in Patients Undergoing Surgery for Stage II, III, IV Esophageal Cancer
Status: COMPLETED
Conditions: Esophageal Cancer
Interventions: DRUG: capecitabine|DRUG: oxaliplatin|GENETIC: gene expression analysis|GENETIC: microarray analysis|GENETIC: reverse transcriptase-polymerase chain reaction|PROCEDURE: adjuvant therapy|PROCEDURE: biopsy|PROCEDURE: conventional surgery|PROCEDURE: neoadjuvant therapy|PROCEDURE: quality-of-life assessment|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Safety, Tolerability and Preliminary Efficacy of NLX-112 Versus Placebo in L-dopa-induced Dyskinesia
Status: COMPLETED
Conditions: Medication-Induced Dyskinesia
Interventions: DRUG: NLX-112|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Swedish Trial on Embolization of Middle Meningeal Artery Versus Surgical Evacuation in Chronic Subdural Hematoma
Status: RECRUITING
Conditions: Chronic Subdural Hematoma
Interventions: PROCEDURE: Endovascular treatment of the middle meningeal artery|PROCEDURE: Standard neurosurgical hematoma evacuation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Developing and Optimizing Transcranial Magnetic Stimulation for Motor Rehabilitation
Status: NOT_YET_RECRUITING
Conditions: Motor Cortex|Motor Skills
Interventions: DEVICE: Transcranial Magnetic Stimulation (TMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Administration of Intranasal Midazolam for Anxiety in Palliative Care
Status: NOT_YET_RECRUITING
Conditions: Anxiety|Acute Anxiety
Interventions: DRUG: Placebo Nasal Spray 0 mg/spray|DRUG: Midazolam Nasal Spray 0.45 mg/spray|DRUG: Midazolam Nasal Spray 0.9 mg/spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Diagnostic Performance of [18F]PSMA-1007 PET/CT Imaging in Patients With Newly-Diagnosed Prostate Cancer
Status: RECRUITING
Conditions: Prostate Cancer
Interventions: DRUG: [18F]PSMA-1007
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Prevention of Broncho-aspiration (BA) in Adult Subjects During Their ICU Stay
Status: COMPLETED
Conditions: Bronchial Aspiration
Interventions: OTHER: Bed Head elevation, H2 blockers and mouth wash|OTHER: Data collection for comparison
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: D-dimer to Improve Anticoagulation Outcome During ECMO loNg-term supporteD
Status: ACTIVE_NOT_RECRUITING
Conditions: Extracorporeal Membrane Oxygenation Complication|Thrombosis|Hemorrhage|Heparin Overdose
Interventions: DIAGNOSTIC_TEST: D-dimer-guided adjustment stratege|DIAGNOSTIC_TEST: Thepeautic-heparin therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Impact of Disease and Visual Disability on Quality of Life and Loss of Independence of Patients Living in France With Leber's Hereditary Optic Neuropathy (LHON) Through Qualitative and Quantitative Data Collection
Status: COMPLETED
Conditions: Leber's Hereditary Optic Neuropathy (LHON)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Indoor Air Pollutants and Their Impact in Childhood Health and Wellbeing
Status: NOT_YET_RECRUITING
Conditions: Asthma in Children|Allergy
Interventions: OTHER: Performing lung function tests (spirometry and fraction of exhaled nitric oxide (FeNO))|OTHER: Filling of standardized questionnaires|OTHER: Using an App on a device|OTHER: Urine sample|OTHER: Sensors and devices will be used to assess air pollutants in classrooms during the survey
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Exercise in OI
Status: COMPLETED
Conditions: Orthostatic Intolerance|Postural Tachycardia Syndrome
Interventions: DRUG: Propranolol then Placebo|DRUG: Placebo then Propranolol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Torsion Optimization to Reduce Symptoms and Improve Outcomes in Non-responders
Status: UNKNOWN
Conditions: Heart Failure, Congestive
Interventions: OTHER: Torsion optimized|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Systemic Air Embolism After CT-guided Lung Biopsy
Status: COMPLETED
Conditions: Patients Who Underwent Percutaneous Lung Biopsy Under CT Guidance|Patients Who Presented Systemic Air Embolism After Percutaneous Lung Biopsy Under CT Guidance Depicted at the Time of the Procedure on a Whole Thoracic CT
Interventions: PROCEDURE: Percutaneous lung biopsy under CT guidance
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Caregiver Burden, Quality of Life, and Symptom Distress at Different Palliative Cancer Care Settings
Status: COMPLETED
Conditions: Advanced Malignant Neoplasm|Locally Advanced Malignant Neoplasm|Metastatic Malignant Neoplasm|Recurrent Malignant Neoplasm
Interventions: OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Application of a Reimbursable Form of Constraint-Induced Movement Therapy for Upper Extremity
Status: COMPLETED
Conditions: CVA (Cerebrovascular Accident)|Stroke|Upper Extremity Paresis
Interventions: BEHAVIORAL: Keys Constraint-induced Movement Therapy protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety And Effectiveness Of Daily Dosing With 37.5 mg Sunitinib Malate In Patients With Advanced Kidney Cancer
Status: COMPLETED
Conditions: Carcinoma, Renal Cell
Interventions: DRUG: Sunitinib malate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Validity Study of Glutamine to Improve Cardiac Function in Cardiac Surgery
Status: COMPLETED
Conditions: Rheumatic Heart Disease|Coronary Heart Disease
Interventions: DRUG: Glutamine|DRUG: Ringer's solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Effect of Omalizumab on Markers of Asthma Impairment in Patients With Persistent Allergic Asthma
Status: COMPLETED
Conditions: Persistent Allergic Asthma
Interventions: DRUG: Omalizumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: E3810-A001-313: Efficacy and Safety of 10 mg Rabeprazole for Treating Heartburn in Frequent Sufferers
Status: COMPLETED
Conditions: Heartburn
Interventions: DRUG: rabeprazole sodium|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Application of Economics & Social Psychology to Improve Opioid Prescribing Safety (AESOPS): R21 Pilot Phase
Status: COMPLETED
Conditions: Opioid Use, Unspecified
Interventions: BEHAVIORAL: Opioid naive|BEHAVIORAL: At-risk for long term use|BEHAVIORAL: Long-term opioid recipient
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: NEW MONITORING IN DIFFERENTIAL DIAGNOSIS OF HYPERLACTATHEMIA IN CARDIOPULMONARY BYPASS SURGERY
Status: COMPLETED
Conditions: Etiology of Hyperlactathemia|Early Period After Cardiopulmonary Bypass Surgery|Washout Phenomenon
Interventions: DEVICE: Near infrared spectroscopy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: SERUR: COVID-19 Serological Survey of Staff From the University Reims-Champagne Ardennes
Status: COMPLETED
Conditions: Covid19
Interventions: DIAGNOSTIC_TEST: Anti-SARS-CoV2 Serology
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: PROCO Neck: The Course and Neuroplasticity in Neck Pain-Associated Disorders and Whiplash-Associated Disorders
Status: NOT_YET_RECRUITING
Conditions: Neck Pain|Whiplash|Pain, Acute|Psychosocial Functioning|Activity, Motor|Alteration of Cognitive Function|Pain, Chronic|Pain Catastrophizing|Overactivity; Behavior
Interventions: OTHER: no intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Docetaxel and Gemcitabine Compared With Docetaxel and Cisplatin in Treating Patients With Metastatic or Locally Advanced Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DRUG: cisplatin|DRUG: docetaxel|DRUG: gemcitabine hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Effects of Multiple-Session tDCS on Behavioral, Physiological, and Electrophysiological Measures With Autistic Adults
Status: NOT_YET_RECRUITING
Conditions: Autism Spectrum Disorder|Autism or Autistic Traits
Interventions: DEVICE: Anodal tDCS + Social Learning|BEHAVIORAL: Placebo Anodal tDCS + Social Learning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Zimmer Biomet Mymobility Application on Reverse Total Shoulder Arthroplasty (RTSA) Outcomes
Status: ENROLLING_BY_INVITATION
Conditions: Reverse Total Shoulder Arthroplasty|Physical Therapy
Interventions: OTHER: mymobility Physical Therapy|OTHER: Standard Office-based Physical Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Efficacy of Manual Toothbrushes in Removing Dental Plaque
Status: COMPLETED
Conditions: Dental Plaque|Oral Hygiene
Interventions: OTHER: Oral B Indicator 123|OTHER: Dr Best Original|OTHER: Dr Best Multi Expert|OTHER: parodontax Interdental
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Phase 2 Spectra Study to Evaluate the Safety and Efficacy of OPL-0401 in Patients With Diabetic Retinopathy
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-proliferative Diabetic Retinopathy|Proliferative Diabetic Retinopathy
Interventions: DRUG: OPL-0401 Dose 1|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT