pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Clinical Study of Neoadjuvant Therapy With Apatinib and Paclitaxel in Local Advanced Triple-negative Breast Cancer
Status: UNKNOWN
Conditions: Triple Negative Breast Cancer
Interventions: DRUG: Apatinib|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vinorelbine and Bevacizumab in Treating Older Patients With Stage III or Stage IV Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer
Interventions: BIOLOGICAL: bevacizumab|DRUG: vinorelbine tartrate
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Role of Surgery of the Primary Tumour in Patients With Synchronous Unresectable Metastases of Colorectal Cancer
Status: COMPLETED
Conditions: Colon Cancer|Primary Tumour|Rectal Cancer
Interventions: PROCEDURE: Surgery of the primary tumour|DRUG: Systemic treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Temozolomide All-Case-Registered Surveillance (Designated Drug Use Investigation)(Study P05062)
Status: COMPLETED
Conditions: Glioma|Astrocytoma
Interventions: DRUG: Temozolomide (for newly diagnosed malignant glioma)|DRUG: Temozolomide (for relapsed malignant glioma)|RADIATION: Radiotherapy (for patients with newly diagnosed malignant glioma)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Safety and Efficacy of Long-term Treatment of PINS Stimulator System for Tourette Syndrome
Status: UNKNOWN
Conditions: Tourette Syndrome
Interventions: DEVICE: deep brain stimulation (DBS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Beta-blockers or Placebo for Primary Prophylaxis (BOPPP) of Oesophageal Varices Trial.
Status: RECRUITING
Conditions: Cirrhosis, Liver|Portal Hypertension|Variceal Hemorrhage|Varices, Esophageal
Interventions: DRUG: Carvedilol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Open-Label, Phase 1 Study to Evaluate Duration of Severe Neutropenia After Same-Day Dosing of Eflapegrastim in Patients With Breast-Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Neutropenia|Breast Cancer
Interventions: BIOLOGICAL: Eflapegrastim|BIOLOGICAL: Eflapegrastim|BIOLOGICAL: Eflapegrastim|BIOLOGICAL: Eflapegrastim|DRUG: Docetaxel|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TENS to Alleviate the Effect of Thirty After Surgery Xerostomia (Dry Mouth) After Surgery
Status: COMPLETED
Conditions: Postoperative Complications
Interventions: DEVICE: Transcutaneous electrical nerve stimulation (TENS)|OTHER: routine care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of Immunogenicity Bridging of a Recombinant New Coronavirus（COVID-19） Vaccine (CHO Cell)
Status: COMPLETED
Conditions: COVID-19
Interventions: BIOLOGICAL: Recombinant new coronavirus vaccine (CHO cell)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Multimedia Training for Family Caregivers in Use of Touch and Massage in Supportive Cancer Care
Status: COMPLETED
Conditions: Cancer
Interventions: BEHAVIORAL: Attention control (reading)|BEHAVIORAL: Touch, Caring and Cancer DVD program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Sunitinib Malate or Sorafenib Tosylate in Treating Patients With Kidney Cancer That Was Removed By Surgery
Status: COMPLETED
Conditions: Clear Cell Renal Cell Carcinoma|Stage I Renal Cell Cancer AJCC v6 and v7|Stage II Renal Cell Cancer AJCC v7|Stage III Renal Cell Cancer AJCC v7
Interventions: OTHER: Laboratory Biomarker Analysis|OTHER: Placebo|OTHER: Quality-of-Life Assessment|DRUG: Sorafenib Tosylate|DRUG: Sunitinib Malate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: MILADY: A Randomized, Placebo-controlled Safety and Efficacy Trial of SSR240600C in Treatment of Overactive Bladder or Urge Urinary Incontinence.
Status: COMPLETED
Conditions: Overactive Bladder
Interventions: DRUG: SSR240600C|DRUG: Placebo|DRUG: Tolterodine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Hysteroscopic Morcellator in Hysteroscopic Treatment of Submucosal Fibroids
Status: UNKNOWN
Conditions: Evaluate Both Technics on Procedure Duration|Characteristics and Perioperative Complications
Interventions: DEVICE: morcellator uterine system (MH)Karl Storz, Tuttligen- Germany
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Individualizing Anti-Inflammatory Medications for Adults With Axial Spondyloarthritis: A Series of N-of 1 Trials
Status: TERMINATED
Conditions: Axial Spondyloarthritis
Interventions: DRUG: Celecoxib|DRUG: Naproxen|DRUG: Meloxicam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Decitabine as Maintenance Therapy After Standard Therapy in Treating Patients With Previously Untreated Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Acute Myeloid Leukemia|Acute Myeloid Leukemia With Myelodysplasia-Related Changes|Adult Acute Myeloid Leukemia With Inv(16)(p13.1q22); CBFB-MYH11|Adult Acute Myeloid Leukemia With t(16;16)(p13.1;q22); CBFB-MYH11|Adult Acute Myeloid Leukemia With t(8;21); (q22; q22.1); RUNX1-RUNX1T1|Adult Acute Myeloid Leukemia With t(9;11)(p22.3;q23.3); MLLT3-KMT2A|Untreated Adult Acute Myeloid Leukemia
Interventions: PROCEDURE: Autologous Bone Marrow Transplantation|PROCEDURE: Autologous Hematopoietic Stem Cell Transplantation|DRUG: Busulfan|DRUG: Cytarabine|DRUG: Daunorubicin Hydrochloride|DRUG: Decitabine|DRUG: Etoposide|BIOLOGICAL: Filgrastim|OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacological Study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PEctin Rapid Fentanyl Efficacy Clinical Trial For pAin at Swallowing Undergoing radioTherapy
Status: WITHDRAWN
Conditions: Predictable BTP at Swallowing in in Head/Neck Cancer Patients Undergoing Radiotherapy Already Receiving Opioid Therapy for Background Pain
Interventions: DRUG: Fentanyl pectin nasal spray (FPNS)|DRUG: Physician choice-Usual care (PC-UC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Clinical Outcomes of Deep Brain Stimulator (DBS) Electrodes Placed Using Intraoperative Computed Tomography (CT) and Frameless Stereotaxis
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DEVICE: Deep Brain Stimulation|PROCEDURE: DBS surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Trial GA101 Inbrutinib B CLL
Status: COMPLETED
Conditions: Leukemia, Lymphocytic, Chronic, B-Cell
Interventions: DRUG: GA101|DRUG: Ibrutinib|DRUG: Cyclophosphamide|DRUG: Fludarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Moxibustion Combined With Characteristic Lifestyle Intervention of Traditional Chinese Medicine in the Treatment of Abdominal Obesity: A Study Protocol for a Randomized Controlled Trial
Status: UNKNOWN
Conditions: Obesity
Interventions: DEVICE: moxibustion combined with characteristic lifestyle intervention of traditional chinese medicine|DEVICE: Moxibustion combined with lifestyle intervention.|DEVICE: lifestyle intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Transcatheter Mitral Valve Replacement in Patients With Severe Symptomatic Mitral Regurgitation - APOLLO-EU Trial
Status: RECRUITING
Conditions: Mitral Regurgitation
Interventions: DEVICE: Medtronic Intrepid™ TMVR TF System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: [18F] FACBC and [18F] FLT PET Imaging in Central Nervous System Tumors
Status: COMPLETED
Conditions: Brain Cancer|Gliomas
Interventions: RADIATION: [18F]FACBC PET and [18F]FLT PET imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose Escalation and Efficacy Study of mRNA-2416 for Intratumoral Injection Alone and in Combination With Durvalumab for Participants With Advanced Malignancies
Status: TERMINATED
Conditions: Relapsed/Refractory Solid Tumor Malignancies or Lymphoma|Ovarian Cancer
Interventions: BIOLOGICAL: mRNA-2416|BIOLOGICAL: Durvalumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Developing Optimal Parameters for Hyperpolarized Noble Gas and Inert Fluorinated Gas MRI of Lung Disorders
Status: RECRUITING
Conditions: Lung Transplant|Lung Resection|Lung Cancer|Asthma|Cystic Fibrosis|Chronic Obstructive Pulmonary Disease|Emphysema|Mesothelioma|Asbestosis|Pulmonary Embolism|Interstitial Lung Disease|Pulmonary Fibrosis|Bronchiectasis|Seasonal Allergies|Cold Virus|Lung Infection|Pulmonary Hypertension|Pulmonary Dysplasia|Obstructive Sleep Apnea
Interventions: DRUG: HP 3He|DRUG: HP 129Xe|DRUG: PFP|DRUG: SF6|DEVICE: 129Xe Small and Large Human Lung Coil|DEVICE: 3He Human Lung Coil|DEVICE: PFP and SF6 Human Lung Coil
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effect of Ginger and Peppermint on Postoperative Nausea and Vomiting in Patients After Thyroid Surgery
Status: UNKNOWN
Conditions: Postoperative Nausea and Vomiting
Interventions: OTHER: Ginger|OTHER: Peppermint
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Rapid Hormonal Cycling as Treatment for Patients With Prostate Cancer: The Men's Cycle
Status: COMPLETED
Conditions: Prostate|Cancer|Hormonal Cycling
Interventions: DRUG: GnRH|DRUG: Ketoconazole|DRUG: Bicalutamide|DRUG: Testosterone transdermal gel|DRUG: Estrogen transdermal patch
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Leucine and Beta-hydroxy-beta-methylbutyrate (HMB) as Anabolic Nutrients After 36 Hours of Fasting
Status: COMPLETED
Conditions: Fasting|Metabolism|Nutrition Support
Interventions: DIETARY_SUPPLEMENT: low leucine content drink|DIETARY_SUPPLEMENT: high leucine content drink|DIETARY_SUPPLEMENT: low leucine + HMB drink|DIETARY_SUPPLEMENT: Control/carbohydrate|BEHAVIORAL: 36 hour fasting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Ovarian Injection of PRP (Platelet -Rich Plasma) Vs Normal Saline in Premature Ovarian Insufficiency
Status: UNKNOWN
Conditions: Premature Ovarian Failure
Interventions: BIOLOGICAL: platelet rich plasma|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Enhancement of Physical and Combat Preparedness of SAF Members - Validation Study
Status: COMPLETED
Conditions: Physical Fitness|Cardio Respiratory Fitness|Aerobic Capacity|Physical Examination|Combat Preparedness
Interventions: DIAGNOSTIC_TEST: Cardio Respiratory Fitness testing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: To Evaluate the Safety and Efficacy of GC1111 (Recombinant Human Iduronate-2-sulfatase) in Hunter Syndrome Patients
Status: COMPLETED
Conditions: Mucopolysaccharidosis II
Interventions: DRUG: GC1111_0.5mg/kg|DRUG: GC1111_1.0mg/kg|DRUG: Elaprase_0.5mg/kg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Efficacy and Safety of Valoctocogene Roxaparvovec, With Prophylactic Steroids in Hemophilia A
Status: ACTIVE_NOT_RECRUITING
Conditions: Hemophilia A
Interventions: BIOLOGICAL: valoctocogene roxaparvovec
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Effectiveness Study Comparing Fluticasone Furoate (FF, GW685698)/Vilanterol (VI, GW642444) With Standard Treatment in Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: fluticasone furoate + vilanterol|DRUG: inhaled corticosteroid with or without a long acting beta2-agonist
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Identifying Responders to Xolair (Omalizumab) Using Eosinophilic Esophagitis as a Disease Model
Status: COMPLETED
Conditions: Eosinophilic Esophagitis
Interventions: BIOLOGICAL: Omalizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: COMPARISON OF LAPAROSCOPY AND ULTRASOUND ASSISTED TRANSVERSUS ABDOMINIS PLANE BLOCK METHODS IN LAPAROSCOPIC TOTAL EXTRAPERITONEAL HERNIA REPAIR
Status: UNKNOWN
Conditions: Postoperative Pain|Inguinal Hernia|Transversus Abdominis Plane Block
Interventions: PROCEDURE: Ultrasound assisted - Laparoscopy assisted Transversus Abdominis Plane Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: TransCon (TC) TLR7/8 Agonist, TC IL-2 β/γ, Pembrolizumab Prior to Surgery for Advanced Head and Neck Squamous Cell Carcinoma
Status: RECRUITING
Conditions: Head and Neck Neoplasms
Interventions: DRUG: TransCon TLR7/8 Agonist|DRUG: Pembrolizumab|DRUG: TransCon IL-2 β/γ
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chronic Kidney Disease Antidepressant Sertraline Trial
Status: COMPLETED
Conditions: Chronic Kidney Disease|Depression
Interventions: DRUG: Sertraline|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Thoracoscopic Pleural Lavage and Brushing in Undiagnosed Pleural Effusion
Status: NOT_YET_RECRUITING
Conditions: Disorder of Pleura and Pleural Cavity
Interventions: PROCEDURE: medical thoracoscope|DIAGNOSTIC_TEST: Forceps biopsy and pleural brush histopathology|DIAGNOSTIC_TEST: pleural lavage cytology
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Study of Eustachian Tube Dysfunction and Laryngopharyngeal Reflux
Status: WITHDRAWN
Conditions: Eustachian Tube Dysfunction|Laryngopharyngeal Reflux
Interventions: DRUG: Omeprazole|DRUG: Ranitidine|DRUG: Pantoprazole|PROCEDURE: 24-Hour Diagnostic pH-Probe Test|PROCEDURE: Laryngoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Clinical Trial for Primary Molar Pulpotomy, Biodentine Vs Formocresol-ZOE
Status: COMPLETED
Conditions: Deep Dental Caries
Interventions: PROCEDURE: Pulpotomies with Formocresol/OZE and Biodentine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of LY2484595 in Healthy Subjects
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: LY2484595 Reference Formulation (RF)|DRUG: LY2484595 spray-dried solid dispersion-propyl gallate (SDSD-PG)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Clinical Trial Comparing Tranexamic Acid (TXA) With Aquamantys Sealer in Total Knee Arthroplasty (TKA)
Status: COMPLETED
Conditions: Blood Loss
Interventions: DRUG: Tranexamic Acid|DEVICE: Aquamantys System|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Digital Interventions to Understand and Mitigate Stress Response
Status: COMPLETED
Conditions: Distress, Emotional|Stress Response Among Nursing Professionals During the COVID-19|Stress Reaction; Acute
Interventions: BEHAVIORAL: Digital Intervention Group
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effects of High-intensity Interval Training and Aerobic Exercise on Obstructive Sleep Apnea.
Status: UNKNOWN
Conditions: Respiratory Function Loss|Exercise Capacity|Fatigue|Selective Attention|Physical Parameters
Interventions: OTHER: Aerobic Exercise, High Intensity Interval Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Incidence of Cancer in the Follow-up of Women With 3 Consecutive Embryonic Demises Before 10 Weeks or 1 Fetal Death, According to Their Thrombophilia Status, With a Special Focus on Women With an Obstetric Antiphospholipid Symdrome (oAPS)
Status: COMPLETED
Conditions: Antiphospholipid Syndrome|Pregnancy Related|Cancer
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparing Patients After ESWL Treated With Ureteral Stents Versus Expulsion Therapy With Tamsulosin
Status: UNKNOWN
Conditions: Upper Tract Ureterolithiasis
Interventions: DRUG: Tamsulosin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Adaptive Deep Brain Stimulation to Improve Motor and Gait Functions in Parkinson's Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Parkinson Disease
Interventions: DEVICE: Summit RC+S|DEVICE: Summit RC+S|DEVICE: Summit RC+S|DEVICE: Summit RC+S
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ketamine Infusion for Acute Sickle Cell Crisis in the Emergency Department
Status: TERMINATED
Conditions: Pain|Sickle Cell Disorder
Interventions: DRUG: Normal saline|DRUG: Ketamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Analgesic Effect of Bilateral Erector Spinae Plane Block With Ropivacaine After Sternotomy for Cardiac Surgery
Status: COMPLETED
Conditions: Cadiac Surgery|Median Sternotomy|Regional Anesthesia|Postoperative Pain
Interventions: DRUG: Ropivacaine 0,2% Injectable Solution|OTHER: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Camrelizumab in Combination With Anlotinib in Subjects Advanced Ovarian Clear Cell Carcinoma
Status: NOT_YET_RECRUITING
Conditions: Ovarian Clear Cell Carcinoma
Interventions: DRUG: Camrelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: "Clinical Evaluation of Opto-Acoustic Tomography for Detection and Diagnostic Differentiation of Thyroid Nodules"
Status: TERMINATED
Conditions: Feasibility Study for Thyroid Indication
Interventions: DEVICE: Imagio OA/US
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of a Soluble Fibre Blend and Medium Chain Triglycerides on Body Composition and Cardiometabolic Risk Factors
Status: COMPLETED
Conditions: People Who Are Overweight or Obesity
Interventions: DIETARY_SUPPLEMENT: soluble fibre complex and medium chain triglycerides|DIETARY_SUPPLEMENT: cellulose and soybean oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cryotherapy and Doppler in Inflammatory Rheumatic Diseases
Status: COMPLETED
Conditions: Rheumatoid Arthritis|Crystal-induced Arthritides|Spondyloarthritis
Interventions: DEVICE: ice|DEVICE: cold gas
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II Iressa & Carbo/Gem in NSCLC
Status: COMPLETED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: Gefitinib|DRUG: Gemcitabine|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preserved Umbilical Vein Use as Autologous Shunt Conduits in Neonatal Cardiac Surgery
Status: COMPLETED
Conditions: Congenital Heart Defects
Interventions: PROCEDURE: Preserved umbilical vein as shunt/conduit
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bevacizumab and Rucaparib in Recurrent Carcinoma of the Cervix or Endometrium
Status: COMPLETED
Conditions: Cervical Cancer|Endometrial Cancer
Interventions: DRUG: Rucaparib|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PS-341 in Treating Patients With Hematologic Cancer
Status: COMPLETED
Conditions: Leukemia|Lymphoma|Multiple Myeloma and Plasma Cell Neoplasm|Myelodysplastic Syndromes
Interventions: DRUG: bortezomib
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Use of Tilapia Skin (Oreochromis Niloticus), in the Treatment of Burn Wounds
Status: COMPLETED
Conditions: Burns
Interventions: DRUG: Sulfadiazine, Silver|DEVICE: Skin of Nile tilapia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Femoral Neck System and Multiple Cannulated Screws in Femoral Neck Fracture
Status: RECRUITING
Conditions: Femoral Neck Fractures
Interventions: DEVICE: Femoral Neck System|DEVICE: Multiple Cannulated Screw
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Three Types of Nucleotide/Nucleoside Analogues Therapy in Patients With Hepatitis b Virus Related Compensated Cirrhosis
Status: UNKNOWN
Conditions: Hepatitis B|Compensated Cirrhosis
Interventions: DRUG: Entecavir|DRUG: Tenofovir Disoproxil Fumarate|DRUG: Tenofovir alafenamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Locomotion Training With Assistance of a Robot-Driven Gait Orthosis in Hemiparetic Patients After Subacute Stroke
Status: COMPLETED
Conditions: Stroke|Hemiparetic Patients After Subacute Stroke
Interventions: OTHER: Robot-assisted gait therapy|OTHER: conventional gait training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Toxins Removal and Inflammatory State modulAtion During Online Hemodiafiltration: Comparison of Two Different Dialyzers
Status: UNKNOWN
Conditions: Hemodialysis Complication|Inflammation|Uremic; Toxemia
Interventions: DEVICE: 1) high flux hemodiafiltration thrice -weekly during a 24 month follow-up
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Patient-Centered Approach to Improve Screening for Side Effects of Second Generation Antipsychotics (SGAs)
Status: COMPLETED
Conditions: Schizophrenia|Psychotic Disorders
Interventions: BEHAVIORAL: Patient-centered computerized tool|BEHAVIORAL: Written educational materials
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Dose Ranging Study of Amlitelimab in Adult Participants With Moderate-to-severe Asthma
Status: ACTIVE_NOT_RECRUITING
Conditions: Asthma
Interventions: DRUG: Amlitelimab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Efficacy and Safety of Intravenous Pamrevlumab, in Hospitalized Participants With Acute COVID-19 Disease
Status: TERMINATED
Conditions: COVID-19
Interventions: DRUG: Pamrevlumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Hypoxia Inducible Factor and Autophagy Related Genes in Patients With Non-Segmental Vitiligo
Status: RECRUITING
Conditions: Vitiligo
Interventions: DEVICE: Punch Biopsy 5mm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Trial of Cabozantinib (XL184) in Non-Small Cell Lung Cancer With Brain Metastases
Status: TERMINATED
Conditions: Non Small Cell Lung Cancer (NSCLC)|Metastases to the Brain
Interventions: DRUG: cabozantinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate eFT508 Alone and in Combination With Avelumab in Subjects With MSS Colorectal Cancer
Status: COMPLETED
Conditions: Microsatellite Stable Relapsed or Refractory Colorectal Cancer
Interventions: DRUG: eFT508|DRUG: Avelumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: IMMNC-HF: IntraMyocardial Injection of Bone Marrow MonoNuclear Cells in Heart Failure (HF) Patients
Status: UNKNOWN
Conditions: Heart Failure
Interventions: BIOLOGICAL: Intramyocardial injection of stem cell|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Prospective Cohort Study on the Prediction of PHLF by Comparing the Prediction Model Based on VEGFA and PEDF With Indocyanine Green Clearance Test
Status: NOT_YET_RECRUITING
Conditions: Liver Failure After Operative Procedure
Interventions: PROCEDURE: Extensive hepatectomy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Using Transcranial Magnetic Stimulation (TMS) to Understand Hallucinations in Schizophrenia
Status: RECRUITING
Conditions: Schizophrenia|Schizo Affective Disorder
Interventions: DEVICE: Repetitive Transcranial Magnetic Stimulation (rTMS)|DEVICE: Sham Repetitive Transcranial Magnetic Stimulation (rTMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Retroperitoneal Ligation of Uterine Artery in Total Laparoscopic Hysterectomy for Enlarged Uterus
Status: SUSPENDED
Conditions: Hysterectomy
Interventions: PROCEDURE: Retroperitoneal liagation of uterine artery|PROCEDURE: Classical ligation of uterine artery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Phenylephrine 2.5%-Tropicamide 1% Microdose Ophthalmic Solution for Pupil Dilation
Status: COMPLETED
Conditions: Mydriasis
Interventions: DRUG: Tropicamide/Phenylephrine ophthalmic solution (TR/PE)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparison of Analgesic Efficacy in Video-Assisted Thoracoscopic Surgery Patients
Status: COMPLETED
Conditions: Video-Assisted Thoracoscopic Surgery
Interventions: PROCEDURE: erector spina plan block|PROCEDURE: Serratus posterior superior intercostal plan block (SPSIPB)|DRUG: 0.25% bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of the Sterile Single-use Circular Stapling Device CIRCCURER II (Jiangxi Langhe Medical Instrument Co., Ltd., Guangzhou, China)
Status: UNKNOWN
Conditions: Phimosis|Foreskin; Tightness|Redundant Prepuce
Interventions: DEVICE: Circumcision in adults using sterile single-use circular stapling device|PROCEDURE: Circumcision in adults
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Efficacy and Safety Study of Two Dose Levels of Certolizumab Pegol (CZP) in Subjects With Plaque Psoriasis (PSO)
Status: COMPLETED
Conditions: Psoriasis|Plaque Psoriasis
Interventions: BIOLOGICAL: Certolizumab Pegol|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Study of Bintrafusp Alfa in Recurrent/Metastatic Olfactory Neuroblastoma (BARON).
Status: ACTIVE_NOT_RECRUITING
Conditions: Olfactory Neuroblastoma|Esthesioneuroblastoma|Neoplasm of the Nasal Cavity
Interventions: DRUG: Bintrafusp alfa / M7824
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Carboplatin Plus Paclitaxel or Docetaxel in Treating Patients With Ovarian Epithelial Cancer
Status: COMPLETED
Conditions: Ovarian Cancer|Primary Peritoneal Cavity Cancer
Interventions: DRUG: carboplatin|DRUG: docetaxel|DRUG: paclitaxel|PROCEDURE: surgical procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Letrozole or Tamoxifen Citrate in Treating Older Postmenopausal Women Undergoing Surgery for Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: letrozole|DRUG: tamoxifen citrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Internet-based Diabetes Education and Case Management
Status: COMPLETED
Conditions: Diabetes Mellitus|Hypertension
Interventions: PROCEDURE: Web-based care management|PROCEDURE: Telephone and face-to-face care management|PROCEDURE: Internet access alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Peripheral Stem Cell Transplantation With Specially Treated Stem Cells in Treating Patients With Non-Hodgkin's Lymphoma or Hodgkin's Disease
Status: WITHDRAWN
Conditions: Lymphoma
Interventions: DRUG: carmustine|DRUG: cyclophosphamide|DRUG: cytarabine|DRUG: dexamethasone|DRUG: etoposide|DRUG: filgrastim|DRUG: mitoxantrone hydrochloride|DRUG: retrovirus vector LN|PROCEDURE: in vitro-treated peripheral blood stem cell transplantation|PROCEDURE: peripheral blood stem cell transplantation|PROCEDURE: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Whole Body Vibration and External Load Exercise Training on Cardiovascular and Autonomic Function in Obese Individuals
Status: COMPLETED
Conditions: Obesity
Interventions: OTHER: Unloaded-Whole Body Vibration (WBVT)|OTHER: Loaded-Whole Body Vibration (WBVT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Cardioprotective Effect of RIPC in Patients Undergoing TAVI
Status: WITHDRAWN
Conditions: Effectivity of RIPC in Outcomes of TAVI Procedure
Interventions: OTHER: without RIPC|PROCEDURE: RIPC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Conservative Management for PAS Pilot
Status: RECRUITING
Conditions: Placenta Accreta
Interventions: PROCEDURE: Conservative management for placenta accreta spectrum (PAS)|PROCEDURE: Cesarean hysterectomy for placenta accreta spectrum (PAS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of RO4917838 in Combination With Antipsychotic Treatment in Patients With Schizophrenia.
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: RO4917838|DRUG: RO4917838|DRUG: RO4917838|DRUG: Placebo|DRUG: Standard antipsychotic therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of an Herbal Topical Cream on Osteoarthritis Symptoms, Biomarkers, and Disease Progression in the Knee
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DRUG: herbal topical cream
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Single Centre, Double-blind, Single and Multiple Ascending Inhaled Doses of AZD9819 in Healthy Subjects
Status: COMPLETED
Conditions: Healthy Volunteers|Safety|Tolerability
Interventions: DRUG: AZD9819|DRUG: AZD9819|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Clinical Study to Compare Two Revascularization Protocols to Treat Non-vital Teeth With Incomplete Root Formation
Status: COMPLETED
Conditions: Dental Pulp Necrosis|Disorder of Tooth Development
Interventions: PROCEDURE: Endodontic Regeneration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Promoting Stress Management and Engagement in Introductory Physics Courses With Mindfulness and Relaxation
Status: ACTIVE_NOT_RECRUITING
Conditions: Psychological Stress|Coping Skills|Emotions|Emotion Regulation
Interventions: BEHAVIORAL: Mindfulness|BEHAVIORAL: Relaxation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study on the Immune Response and Safety of a Vaccine Against N. Meningitidis Serogroup B Infection in Healthy Infants From 2 Months of Age
Status: NOT_YET_RECRUITING
Conditions: Meningitis, Meningococcal
Interventions: BIOLOGICAL: rMenB+OMV NZ
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Vaginal Administration of ALA vs Progesterone for the Subchorionic Hematoma Treatment
Status: COMPLETED
Conditions: Subchorionic Hematoma in the First Trimester Pregnancy|Miscarriage
Interventions: DEVICE: Lipoic acid|DRUG: Progesterone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Research Study of Bipolar Mood Symptoms and Cognitive Problems
Status: COMPLETED
Conditions: Bipolar Disorder
Interventions: DRUG: Valacyclovir|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of a Single-session Implicit Theories of Personality Intervention on Early Adolescent Psychopathology
Status: COMPLETED
Conditions: Anxiety Symptoms|Depressive Symptoms
Interventions: OTHER: Implicit Theories of Personality Program|OTHER: Control Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: YSPSL for Prevention of Delayed Graft Function in Cadaveric Liver Transplantation
Status: UNKNOWN
Conditions: Liver Diseases
Interventions: DRUG: YSPSL|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Efficacy and Safety of Giredestrant in Combination With Phesgo (Pertuzumab, Trastuzumab, and Hyaluronidase-zzxf) Versus Phesgo in Participants With Locally Advanced or Metastatic Breast Cancer (heredERA Breast Cancer)
Status: RECRUITING
Conditions: Locally Advanced or Metastatic Breast Cancer
Interventions: DRUG: Phesgo|DRUG: Giredestrant|DRUG: Docetaxel|DRUG: Paclitaxel|DRUG: LHRH Agonist|DRUG: Optional Endocrine Therapy of Investigator's Choice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study to Determine if Working Memory Training Aids Cognitive Functioning in Patients With Parkinson's Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Parkinson Disease
Interventions: BEHAVIORAL: Adaptive working memory training task|BEHAVIORAL: Non-adaptive working memory training task (i.e. an active control task)|BEHAVIORAL: No training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Plum-blossom Needle vs. Tropicamide Eye Drops on Juvenile Myopia
Status: UNKNOWN
Conditions: Myopia
Interventions: OTHER: Plum-blossom Needle|DRUG: Tropicamide Eye Drops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Accelerometry at the Neck: Comparison With m. Adductor Pollicis Stimulation
Status: COMPLETED
Conditions: Feasibility of Measurement of a Neuromuscular Block at the m. Trapezius
Interventions: DEVICE: accelerometry m. trapezius and m. adductor pollicis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: NPWTi on Closure of Chronic Pressure Sores
Status: RECRUITING
Conditions: Pressure Sore
Interventions: DEVICE: V.A.C.Ulta™ Negative Pressure Wound Therapy System|OTHER: Standard of Care (Wet-to-dry dressings)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sensorimotor Replacement With Electronic and De-nicotinised Cigarettes
Status: COMPLETED
Conditions: Nicotine Withdrawal
Interventions: BEHAVIORAL: Stress Ball vs Nicotine-free E-Cigarette|BEHAVIORAL: Nicotine-free E-Cigarette vs De-nicotinised Cigarette
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Consequences of Changing Current Standards: Endocrine Status After Routine Fallopian Tube Removal
Status: COMPLETED
Conditions: Pelvic Surgery|Routine Fallopian Tube Removal
Interventions: PROCEDURE: Routine fallopian tube removal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparing ATG or Post-Transplant Cyclophosphamide to Calcineurin Inhibitor-Methotrexate as GVHD Prophylaxis After Myeloablative Unrelated Donor Peripheral Blood Stem Cell Transplantation
Status: WITHDRAWN
Conditions: Acute Lymphoblastic Leukemia in Remission|Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome|Chronic Myelomonocytic Leukemia|Chronic Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive|Hematopoietic and Lymphoid System Neoplasm|Myelodysplastic Syndrome|Myelofibrosis|Myeloproliferative Neoplasm|Recurrent Acute Myeloid Leukemia|Recurrent Hodgkin Lymphoma|Recurrent Non-Hodgkin Lymphoma|Refractory Acute Myeloid Leukemia|Therapy-Related Acute Myeloid Leukemia
Interventions: BIOLOGICAL: Anti-Thymocyte Globulin|DRUG: Busulfan|DRUG: Cyclophosphamide|DRUG: Cyclosporine|DRUG: Fludarabine Phosphate|DRUG: Methotrexate|PROCEDURE: Peripheral Blood Stem Cell Transplantation|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration|DRUG: Tacrolimus|RADIATION: Total-Body Irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improvement of EPO-resistance in Hemodialysis Patients With Chronic Inflammation by High Cut-off Hemodialysis
Status: COMPLETED
Conditions: End-Stage Renal Disease (ESRD)
Interventions: DEVICE: Theralite (high cut-off hemodialysis)|DEVICE: Conventional high-flux dialyzer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Insoles Adapted in Flip-flop Sandals in People With Heel Pain
Status: COMPLETED
Conditions: Heel Pain Syndrome|Heel
Interventions: OTHER: Insoles adapted in flip-flop sandals
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Study on the Relationship Among Meridian, Acupoint and Internal Visceral Organs
Status: COMPLETED
Conditions: Meridian
Interventions: OTHER: sham electroacupuncture (EA) session|OTHER: Zusanli session|OTHER: Shaohai session
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Reappraisal of Atrial Fibrillation: Interaction Between HyperCoagulability, Electrical Remodeling, and Vascular Destabilisation in the Progression of Atrial Fibrillation
Status: ACTIVE_NOT_RECRUITING
Conditions: Atrial Fibrillation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of Guselkumab and Interleukin-17 (IL-17) Inhibitor Therapies in Participants With Psoriatic Arthritis in Routine Clinical Practice
Status: ACTIVE_NOT_RECRUITING
Conditions: Arthritis, Psoriatic
Interventions: DRUG: Guselkumab|DRUG: IL-17i
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: 4 Week Correction Study in Subjects With Anemia Associated With Chronic Kidney Disease Who Are Not Undergoing Dialysis
Status: COMPLETED
Conditions: Anaemia
Interventions: DRUG: GSK1278863|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study for Gemigliptin/Metformin 50/1000 mg and Coadministration of Gemigliptin 50 mg and Metformin 1000 mg.
Status: UNKNOWN
Conditions: Type2 Diabetes
Interventions: DRUG: gemigliptin 50 mg and metformin hydrochloride 1000 mg prolonged release|DRUG: Gemigliptin tartrate sesquihydrate and metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sargramostim in Decreasing Mucositis in Patients Receiving Radiation Therapy for Head and Neck Cancer
Status: COMPLETED
Conditions: Head and Neck Cancer|Oral Complications|Radiation Toxicity
Interventions: BIOLOGICAL: sargramostim|PROCEDURE: quality-of-life assessment|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Transbronchial vs Transthoracic Ablation for Early-stage Peripheral Lung Cancer
Status: RECRUITING
Conditions: Stage IA Lung Cancer
Interventions: DEVICE: The disposable pulmonary radiofrequency ablation catheter and pulmonary radiofrequency ablation system|DEVICE: The disposable percutaneous radiofrequency ablation needle and pulmonary radiofrequency ablation system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Exam Findings in Coronavirus Disease 2019 (COVID-19) With Point-of-Care Ultrasonography (POCUS)
Status: COMPLETED
Conditions: Coronavirus Infection|COVID|Covid-19|SARS-CoV-2
Interventions: DIAGNOSTIC_TEST: Point-of-Care Ultrasonography (POCUS)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Just-in-time Elastomeric Training and Fit Testing (JET FIT)
Status: COMPLETED
Conditions: Infection
Interventions: OTHER: Reusable respirator fit test and competency evaluation|OTHER: Control fit test evaluation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Internal Fixation vs Hip Arthroplasty in Older Adults With an Undisplaced Femoral Neck Fracture: A Substudy of the Hipsther Trial
Status: RECRUITING
Conditions: Hip Fractures|Femoral Neck Fractures|Undisplaced Fracture|Treatment Complication|Internal Fixation; Complications|Arthroplasty Complications
Interventions: DEVICE: Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT