pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: An 8-Week Refractory Chronic Cough Study (MK-7264-021)
Status: COMPLETED
Conditions: Refractory Chronic Cough
Interventions: DRUG: Gefapixant|DRUG: Placebo (for gefapixant)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Enduring Exercise Habits
Status: COMPLETED
Conditions: Healthy
Interventions: BEHAVIORAL: Sweet Spot: Flexible high incentive condition|BEHAVIORAL: Sweet Spot: Flexible low incentive condition|BEHAVIORAL: Sweet Spot: Rigid high incentive condition|BEHAVIORAL: Sweet Spot: Rigid low incentive condition|BEHAVIORAL: FOTW: High incentive control condition|BEHAVIORAL: FOTW: Low incentive control condition|BEHAVIORAL: FOTW: High incentive treatment condition|BEHAVIORAL: FOTW: Low incentive treatment condition|BEHAVIORAL: Think Twice: Control condition|BEHAVIORAL: Think Twice: Treatment condition|BEHAVIORAL: WDR: Control condition|BEHAVIORAL: WDR: Treatment condition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of Lumigan® in Patients With Primary Open Angle Glaucoma (POAG) or Ocular Hypertension (OHT)
Status: COMPLETED
Conditions: Glaucoma, Open-Angle|Ocular Hypertension
Interventions: DRUG: bimatoprost 0.01%
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Risk-adapted Therapy in HPV+ Oropharyngeal Cancer Using Circulating Tumor (ct)HPV DNA Profile - The ReACT Study
Status: RECRUITING
Conditions: HPV-Associated Oropharyngeal Squamous Cell Carcinoma|HPV Positive Oropharyngeal Squamous Cell Carcinoma|HPV-Mediated (P16-Positive) Oropharyngeal Carcinoma by AJCC V8 Stage|HPV-Related Squamous Cell Carcinoma|Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8|Pathologic Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8|Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8|Pathologic Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8|Clinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8|Pathologic Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8|HPV-Mediated (P16-Positive) Oropharyngeal Carcinoma by AJCC V8 Clinical Stage|HPV-Mediated (P16-Positive) Oropharyngeal Carcinoma by AJCC V8 Pathologic Stage
Interventions: DEVICE: NavDx HPV ctDNA Testing|RADIATION: Radiotherapy|DRUG: Chemotherapy drug
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Safety and Efficacy of Ruxolitinib Cream in Participants With Genital Vitiligo
Status: ACTIVE_NOT_RECRUITING
Conditions: Nonsegmental Vitiligo With Genital Involvement
Interventions: DRUG: Ruxolitinib Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Sulforaphane (SFN) on Immune Response to Live Attenuated Influenza Virus in Smokers and Nonsmokers
Status: COMPLETED
Conditions: Smoking
Interventions: DIETARY_SUPPLEMENT: Broccoli sprout homogenate|DIETARY_SUPPLEMENT: Alfalfa sprout homogenate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose:
Clinical trial: Phase II Study of Forodesine in Subjects With Chronic Lymphocytic Leukemia (CLL)
Status: COMPLETED
Conditions: Chronic Lymphocytic Leukemia (CLL)
Interventions: DRUG: forodesine HCl
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Imatinib in Combination With Dacarbazine and Capecitabine in Medullary Thyroid Carcinoma
Status: TERMINATED
Conditions: Solid Tumor|Thyroid Cancer
Interventions: DRUG: Capecitabine (Xeloda)|DRUG: DTIC-Dome (Dacarbazine)|DRUG: Gleevec (Imatinib Mesylate)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study of PT-523 in Cancer Patients to Treat Solid Tumors Including a Preliminary Assessment of Effectiveness
Status: TERMINATED
Conditions: Neoplasms
Interventions: DRUG: PT-523 for Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Bioequivalence of Atripla in an Oral Liquid Formulation Compared With the Tablet Formulation in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: tenofovir, emtricitabine and efavirenz fixed dose tablet|DRUG: tenofovir, emtricitabine and efavirenz tablet added to solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: A Study of the Treatment of Postmenopausal Women With Osteoporosis
Status: COMPLETED
Conditions: Osteoporosis, Post-Menopausal
Interventions: DRUG: teriparatide 20 micrograms/day subcutaneous|DRUG: salmon calcitonin 100 IU/day subcutaneous
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination of Atezolizumab and Pirfenidone in Second-line and Beyond NSCLC
Status: RECRUITING
Conditions: NSCLC Stage IV|NSCLC, Recurrent
Interventions: DRUG: Atezolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Patient Self Measurement of Post-Void Residual Bladder Volume (PVR) Using Ultrasound
Status: COMPLETED
Conditions: Voiding Disorders|Voiding Dysfunction
Interventions: DEVICE: Butterfly portable ultrasound device with bladder ultrasound images|DEVICE: Butterfly portable ultrasound device with abstract bladder images
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Efficacy of a Multi-faceted Intervention to Deprescribe Proton Pump Inhibitors (PPI) in Primary Care: a Population-based, Pragmatic, Cluster-randomized Controlled Trial.
Status: COMPLETED
Conditions: Proton Pump Inhibitors|Deprescription
Interventions: OTHER: General practitioner and Patient receive informations related to PPI deprescribing.|OTHER: Only General practitioner receive informations related to PPI deprescribing.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Neoadjuvant Triplet Chemotherapy Regimen in Patients With Resectable Colorectal Cancer
Status: UNKNOWN
Conditions: Colorectal Cancer
Interventions: DRUG: oxaliplatin;irinotecan;leucovorin;5-fluorouracil;capecitabine;S-1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Effectiveness of Bonded Versus Vacuum-formed Retainers
Status: COMPLETED
Conditions: Relapse
Interventions: DEVICE: V-bend Bonded Retainer|DEVICE: Vacuum-formed Retainer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Role of Dry Needling in Hallux Valgus
Status: COMPLETED
Conditions: Hallux Valgus|Myofascial Pain Syndrome
Interventions: OTHER: Toe spread out|OTHER: Dry needling+Toe spread out
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Water And Saline Head-to-head In The Blinded Evaluation Study Trial
Status: COMPLETED
Conditions: Acute Appendicitis|Abscess
Interventions: PROCEDURE: Normal Saline|PROCEDURE: Sterile Water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Impact of Soiled Airway Management on CPR Quality
Status: COMPLETED
Conditions: Airway Aspiration|Cardiopulmonary Arrest
Interventions: DEVICE: SALAD simulation device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Impact of Home Intraocular Pressure Telemonitoring on Intraocular Pressure Control and Glaucoma Progression
Status: NOT_YET_RECRUITING
Conditions: Glaucoma|Intraocular Pressure|Primary Open Angle Glaucoma
Interventions: DEVICE: Standard care and home IOP telemonitoring with smart phone-based intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Short vs Long Arm Cast for Distal Radius Fractures: the Verona Trial
Status: COMPLETED
Conditions: Radius Fracture Distal
Interventions: PROCEDURE: Short arm cast|PROCEDURE: Long arm cast
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: "NAVA-PAV" Study: a Cross-over Comparative Study of 2 Advanced Modes
Status: COMPLETED
Conditions: Critical Illness|Mechanical Ventilation|Intensive Care|Ventilation Weaning
Interventions: OTHER: NAVA ventilatory mode|OTHER: PAV+ ventilatory mode
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Serious Game-based Interventions in Patients With Mild Cognitive Impairment Outside the Clinic
Status: RECRUITING
Conditions: Mild Cognitive Impairment
Interventions: DEVICE: Neuro-World
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Conventional Bronchoscope With BAL vs. Thin Bronchoscope With BW to Diagnose Pulmonary TB
Status: RECRUITING
Conditions: Tuberculosis, Pulmonary
Interventions: DEVICE: bronchial washing using a thin bronchoscope
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Heart Outcomes Prevention Evaluation-3
Status: COMPLETED
Conditions: Cardiovascular Disease|Stroke
Interventions: DRUG: Candesartan/HCT|DRUG: Rosuvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Drug Counseling and Abstinent-Contingent Take-Home Buprenorphine in Malaysia
Status: COMPLETED
Conditions: Opiate Dependence
Interventions: BEHAVIORAL: behavioral drug and HIV risk reduction counseling (BDRC)|BEHAVIORAL: abstinence-contingent buprenorphine (ACB)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Risk of Positive Doping Tests Following Ingestion of Supplements Contaminated With Trace Quantities of Nandrolone Metabolites
Status: COMPLETED
Conditions: Positive Doping Tests in Sports
Interventions: DIETARY_SUPPLEMENT: 19-norandrostendione
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Impact Evaluation of a Social Franchise Model for Improving Infant and Young Child Feeding and Child Nutrition in Vietnam
Status: COMPLETED
Conditions: Child Nutrition|Stunting|Exclusive Breastfeeding|Complementary Feeding
Interventions: BEHAVIORAL: Standard government health services|BEHAVIORAL: Alive & Thrive IYCF franchise services|BEHAVIORAL: Mass media campaign
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparison of Prevena Negative Pressure Incision Management System vs. Standard Dressing After Vascular Surgery
Status: UNKNOWN
Conditions: Peripheral Artery Disease|Critical Limb Ischemia|Claudication
Interventions: OTHER: standard gauze dressing|OTHER: Prevena Incision Management system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: McGrath Mac Videolaryngoscope Versus Macintosh Laryngoscope for Orotracheal Intubation in Critical Care Unit
Status: COMPLETED
Conditions: Intratracheal Intubation in Critical Care
Interventions: DEVICE: Videolaryngoscope|DEVICE: Standard laryngoscope
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: SerUm and Plasma MicroRNAs in Malignant Ovarian gERm Cell Tumours
Status: NOT_YET_RECRUITING
Conditions: Germ Cell Ovarian Cancer|Germ Cell Tumor|Germ Cell Cancer|Germ Cell Neoplasia|Ovary Cancer|Ovary Neoplasm|Ovarian Cancer|Ovarian Neoplasms
Interventions: DIAGNOSTIC_TEST: Blood test|DIAGNOSTIC_TEST: Pathology specimen miRNA expression
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Propofol and Isoflurane on Pulmonary Vascular Resistance
Status: COMPLETED
Conditions: Hypertension, Pulmonary
Interventions: DRUG: propofol and isoflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Multiple Dose Comparison of the Effect of Two Dose Combinations of Tipranavir/Ritonavir (TPV/RTV), on the Pharmacokinetic Characteristics of Efavirenz (Sustiva®) in Healthy Adult Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: EFV|DRUG: TPV/RTV - low dose|DRUG: TPV/RTV - high dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Evaluation of Limb Health Associated With a Prosthetic Vacuum Socket System
Status: UNKNOWN
Conditions: Lower Limb Amputation
Interventions: DEVICE: Prosthetic Suction or Pin Socket|DEVICE: Prosthetic LimbLogic Vacuum Socket
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Group Based Exposure Therapy for Combat-Related PTSD
Status: COMPLETED
Conditions: Posttraumatic Stress Disorder
Interventions: BEHAVIORAL: Group Based Exposure Therapy|BEHAVIORAL: Present Centered Group Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Longitudinal Study for the Characterization of the Phases of Subjective Perception of Cognitive Decline and Mild Cognitive Impairment of Alzheimer's Disease.
Status: RECRUITING
Conditions: Alzheimer Disease|Mild Cognitive Impairment|Subjective Cognitive Decline
Interventions: OTHER: No intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: An Exploratory Study to Evaluate Attention Biases in Adults With Multiple Sclerosis, Breast Cancer, and Lung Cancer
Status: COMPLETED
Conditions: Multiple Sclerosis|Lung Cancer|Breast Cancer
Interventions: DEVICE: CT-100-D-004-A|DEVICE: CT-100-D-004-B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: STAT3 Inhibitor WP1066 in Treating Patients With Recurrent Malignant Glioma or Progressive Metastatic Melanoma in the Brain
Status: COMPLETED
Conditions: Metastatic Malignant Neoplasm in the Brain|Metastatic Melanoma|Recurrent Brain Neoplasm|Recurrent Glioblastoma|Recurrent Malignant Glioma
Interventions: OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacological Study|DRUG: STAT3 Inhibitor WP1066
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral Ifetroban to Treat Aspirin Exacerbated Respiratory Disease (AERD)
Status: COMPLETED
Conditions: Asthma, Aspirin-Induced
Interventions: DRUG: Ifetroban Oral Capsule|DRUG: Placebo Oral Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Early Feasibility Study to Evaluate the Efficacy and Safety of the RenewalNail™ Plasma Treatment System in Patients With Mild to Moderate Onychomycosis (Fungal Nail)
Status: COMPLETED
Conditions: Onychomycosis Due to Trichophyton Rubrum|Onychomycosis Due to Trichophyton Mentagrophytes
Interventions: DEVICE: RenewalNail™ Plasma Treatment System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Efficacy and Safety of Eliglustat Tartrate (Genz-112638) in Type 1 Gaucher Patients
Status: COMPLETED
Conditions: Gaucher Disease, Type 1|Cerebroside Lipidosis Syndrome|Glucocerebrosidase Deficiency Disease|Glucosylceramide Beta-Glucosidase Deficiency Disease|Gaucher Disease, Non-Neuronopathic Form
Interventions: DRUG: Eliglustat tartrate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigation to Evaluate the Efficacy and Safety of Exufiber Versus Aquacel Extra in Moderately or Strongly Exuding Venous and Mixed Ulcers of Predominantly Venous Origin
Status: COMPLETED
Conditions: Venous Leg Ulcer
Interventions: DEVICE: Exufiber Gelling Fibre Dressing|DEVICE: Aquacel Extra Hydrofiber® Dressing with Strengthening Fibre
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of HPN217 in Participants With Relapsed/Refractory Multiple Myeloma MK-4002 (HPN217)
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Myeloma in Relapse|Multiple Myeloma|Multiple Myeloma of Bone|Multiple Myeloma With Failed Remission
Interventions: DRUG: MK-4002
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics of Bendamustine Hydrochloride in Patients With Relapsed or Refractory Malignancy
Status: COMPLETED
Conditions: Malignancy
Interventions: DRUG: bendamustine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Are Carvedilol and Metoprolol Succinate Comparable Treatments in Heart Failure Patients With Reduced Ejection Fraction
Status: NOT_YET_RECRUITING
Conditions: Chronic Heart Failure
Interventions: DRUG: Carvedilol|DRUG: Metoprolol Succinate
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Resistance Exercise Breaks Improve Ratings of Discomfort and Fatigue in College Students (REX)
Status: COMPLETED
Conditions: Sedentary Behavior|Fatigue|Sleepiness|Pain
Interventions: BEHAVIORAL: Resistance Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Urokinase Versus Primary Video-Assisted Thorascopic Surgery for Empyema
Status: COMPLETED
Conditions: Empyema
Interventions: DRUG: insertion of a chest drain with urokinase instillation|PROCEDURE: primary video-assisted thorascopic surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anti-Mesothelin Immunotoxin LMB-100 Followed by Pembrolizumab in Malignant Mesothelioma
Status: TERMINATED
Conditions: Mesothelioma
Interventions: DRUG: LMB-100|BIOLOGICAL: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Experiment Among Smokers in Which Two Variables Are Manipulated: Ostracism and Concealability
Status: NOT_YET_RECRUITING
Conditions: Ostracism
Interventions: BEHAVIORAL: Do men and women differ in their reactions to the experimental conditions.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Ultrasound-guided Percutaneous Neuromodulation in Anterior Cruciate Reconstruction
Status: COMPLETED
Conditions: ACL Injury
Interventions: OTHER: Ultrasound-Guided Percutaneous Neuromodulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: TReatment Of Pulmonary HYpertension 1-US Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Pulmonary Arterial Hypertension
Interventions: DEVICE: Therapeutic Intra-Vascular UltraSound (TIVUS™) System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vitamin D 24'000 IU for Oral Intermittent Supplementation
Status: COMPLETED
Conditions: Vitamin D Deficiency
Interventions: DRUG: Vitamin D3|DRUG: Vitamin D oily capsules|DRUG: Vitamin D oily capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Application of PNE in Postoperative Pain Management of Patients With Primary Total Knee Arthroplasty
Status: COMPLETED
Conditions: Pain
Interventions: BEHAVIORAL: Pain Neuroscience Education|BEHAVIORAL: Routine Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study To Evaluate The Efficacy, Safety, Pharmacokinetics, And Pharmacodynamic Effects Of GDC-6599 In Patients With Chronic Cough
Status: RECRUITING
Conditions: Chronic Refractory Cough (CRC) With Non-atopic Asthma|CRC With Atopic Asthma|Unexplained Chronic Cough|CRC With Chronic Obstructive Pulmonary Disease|CRC With Chronic Obstructive Pulmonary Disease With Chronic Bronchitis
Interventions: DRUG: GDC-6599|OTHER: GDC-6599-matching placebo|DIAGNOSTIC_TEST: Mannitol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Chuna Manual Treatment as an Adjunctive Therapy After Total Knee Arthroplasty: A Study Protocol for a Single-Center, Randomized, Assessor Blind, Parallel-Group Clinical Trial
Status: COMPLETED
Conditions: Total Knee Replacement|Manipulation
Interventions: PROCEDURE: Chuna + Usual care(Celecoxib and esomeprazole)|DRUG: Usual care(Celecoxib and esomeprazole)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dose Escalation Study of MLN0128 in Combination With Paclitaxel, With/Without Trastuzumab, in Subjects With Advanced Solid Malignancies
Status: COMPLETED
Conditions: Advanced Solid Malignancies|Hematologic Malignancies
Interventions: DRUG: MLN0128|DRUG: paclitaxel|DRUG: trastuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Epidemiology and Genetics of the Amyotrophic Lateral Sclerosis in the French West Indies
Status: UNKNOWN
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DIETARY_SUPPLEMENT: Blood sample and environmental survey
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Delta-8-THC vs. Delta-9-THC on Simulated Driving Performance
Status: RECRUITING
Conditions: Cannabis
Interventions: DRUG: Delta-9-THC|DRUG: Delta-8-THC|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Core Stability Exercises and Hereditary Ataxia
Status: COMPLETED
Conditions: Hereditary Ataxia|Spinocerebellar Degenerations|Cerebellar Ataxia
Interventions: OTHER: Therapeutic core stability exercises|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Double-Blind, Randomized, Placebo-controlled Comparison of CC-10004 in Subjects With Moderate to Severe Plaque Type Psoriasis
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: CC-10004|DRUG: CC-10004|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The TG01 Study With TG01/QS-21 Vaccine in Patients With High-risk Smouldering Multiple Myeloma and Multiple Myeloma
Status: RECRUITING
Conditions: Multiple Myeloma|Smoldering Multiple Myeloma
Interventions: BIOLOGICAL: TG01
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics of Sotrovimab as Pre-exposure Prophylaxis for COVID-19 in Hematopoietic Stem Cell Transplant Recipients, COVIDMAB Study
Status: TERMINATED
Conditions: COVID-19 Infection|Hematopoietic and Lymphoid Cell Neoplasm|Malignant Solid Neoplasm
Interventions: OTHER: Questionnaire Administration|BIOLOGICAL: Sotrovimab|PROCEDURE: Biospecimen Collection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effects of TAP Block on Thiol/Disulfide Homeostasis and Pain in Laparoscopic Gynecological Surgery
Status: NOT_YET_RECRUITING
Conditions: Pain, Postoperative|Oxidative Stress
Interventions: OTHER: Transversus abdominis plane (TAP) block
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Cemiplimab, Low-Dose Paclitaxel and Carboplatin for the Treatment of Recurrent/Metastatic Squamous Cell Carcinoma of the Head and Neck
Status: RECRUITING
Conditions: Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8|Metastatic Head and Neck Squamous Cell Carcinoma|Metastatic Hypopharyngeal Squamous Cell Carcinoma|Metastatic Laryngeal Squamous Cell Carcinoma|Metastatic Oral Cavity Squamous Cell Carcinoma|Metastatic Oropharyngeal Squamous Cell Carcinoma|Pathologic Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8|Recurrent Head and Neck Squamous Cell Carcinoma|Recurrent Hypopharyngeal Squamous Cell Carcinoma|Recurrent Laryngeal Squamous Cell Carcinoma|Recurrent Oral Cavity Squamous Cell Carcinoma|Recurrent Oropharyngeal Squamous Cell Carcinoma|Squamous Cell Carcinoma of Unknown Primary|Stage IV Hypopharyngeal Carcinoma AJCC v8|Stage IV Laryngeal Cancer AJCC v8|Stage IV Lip and Oral Cavity Cancer AJCC v8|Stage IVA Hypopharyngeal Carcinoma AJCC v8|Stage IVA Laryngeal Cancer AJCC v8|Stage IVA Lip and Oral Cavity Cancer AJCC v8|Stage IVB Hypopharyngeal Carcinoma AJCC v8|Stage IVB Laryngeal Cancer AJCC v8|Stage IVB Lip and Oral Cavity Cancer AJCC v8|Stage IVC Hypopharyngeal Carcinoma AJCC v8|Stage IVC Laryngeal Cancer AJCC v8|Stage IVC Lip and Oral Cavity Cancer AJCC v8
Interventions: DRUG: Carboplatin|BIOLOGICAL: Cemiplimab|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Topical Pharyngeal Anesthesia With Articaine for Gastroscopy
Status: COMPLETED
Conditions: Gastroscopy
Interventions: DRUG: articaine|OTHER: 9% Sodium Chloride solution for injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Autologous Dendritic Cells and Allogenic Dendritic Secretomes for Patients With Advanced Nasopharyngeal Cancer
Status: UNKNOWN
Conditions: Nasopharyngeal Cancer
Interventions: BIOLOGICAL: Auto-Dendritic Adjuvant Therapy|BIOLOGICAL: Allo-Dendritic-Secretome Adjuvant Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Study of the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ACU-4429 in Subjects With Geographic Atrophy
Status: COMPLETED
Conditions: Dry Age-related Macular Degeneration|Geographic Atrophy
Interventions: DRUG: ACU-4429|DRUG: Matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prognostic Contribution of Abdominal Ultrasound in Necrotizing Enterocolitis in Preterm Infants Less Than 33SA.
Status: UNKNOWN
Conditions: the Necrotizing Enterocolitis|Preterm Infants
Interventions: DEVICE: Abdominal ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Optimal Margin Evaluation of Online Adaptive Radiotherapy for Postoperative Treatment of Endometrial and Cervical Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Uterine Cervical Neoplasm|Endometrial Neoplasms
Interventions: RADIATION: online adaptive radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dexmedetomidine or Clonidine Infusion for Prevention of Delirium After Open Heart Surgery
Status: RECRUITING
Conditions: Delirium|Cognitive Decline|Frailty
Interventions: DRUG: Dexmedetomidine|DRUG: Clonidine|DRUG: Natriumchlorid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Biomakers in Tissue Samples From Patients With Recurrent and/or Metastatic Squamous Cell Cancer of the Head and Neck Previously Treated With Cisplatin With or Without Cetuximab
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: OTHER: immunohistochemistry staining method|OTHER: laboratory biomarker analysis|OTHER: medical chart review
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Ketamine Versus Etomidate for Procedural Sedation for Pediatric Orthopedic Reductions
Status: COMPLETED
Conditions: Conscious Sedation Failure During Procedure
Interventions: DRUG: ketamine and midazolam|DRUG: etomidate, fentanyl, and lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigation of Immediate, Short and Long Term Effects of Mulligan Mobilization With Movement Techniques in Nonspesific Chronic Low Back Pain
Status: COMPLETED
Conditions: Chronic Low Back Pain
Interventions: OTHER: Mulligan mobilization with movement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Mulligan's Mobilization and Proprioceptive Neuromuscular Facilitation Technique in Sacroiliac Joint Dysfunction
Status: UNKNOWN
Conditions: SACROILIAC JOINT DYSFUNCTION
Interventions: OTHER: Mulligan Mobilization|OTHER: PNF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Double-blind Randomized Clinical Trial of Transcranial Magnetic Stimulation in Chronic Migraine
Status: COMPLETED
Conditions: Chronic Migraine
Interventions: DEVICE: 10Hz active rTMS|DEVICE: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Elotuzumab in Combination With Thalidomide and Dexamethasone in Relapsed and/or Refractory Multiple Myeloma
Status: COMPLETED
Conditions: Relapsed and/or Refractory Multiple Myeloma
Interventions: BIOLOGICAL: Elotuzumab|BIOLOGICAL: Thalidomide|BIOLOGICAL: Dexamethasone|BIOLOGICAL: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ibrutinib With Radiation and Temozolomide in Patients With Newly Diagnosed Glioblastoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Glioblastoma
Interventions: DRUG: Ibrutinib|RADIATION: Radiation|DRUG: Temozolomide (TMZ)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lifestyle Modification Program in the Prevention and Treatment of Depression
Status: COMPLETED
Conditions: Depression
Interventions: BEHAVIORAL: Lifestyle Modification Program (LMP)|BEHAVIORAL: Lifestyle Modification Program (LMP) + Information Communication Technologies (ICTs)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bupivacaine vs Oxybuprocaine Topical Anesthesia in IVI
Status: COMPLETED
Conditions: Pain, Acute
Interventions: DRUG: bupivacaine 0.5% and oxubuprocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Resistant Starch in a Beverage on Post-prandial Glycemic and Insulinemic Responses
Status: COMPLETED
Conditions: Hyperglycemia, Diabetes, and Obesity
Interventions: DIETARY_SUPPLEMENT: Resistant Starch|DIETARY_SUPPLEMENT: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of the Use of Irreversible Electroporation in Pancreatic Ductal Cancer
Status: COMPLETED
Conditions: Pancreatic Ductal Adenocarcinoma
Interventions: PROCEDURE: Irreversible Electroporation|DEVICE: NanoKnife System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 506U78 in Treating Patients With Recurrent or Refractory Non-Hodgkin's Lymphoma or T-cell Lymphoma
Status: TERMINATED
Conditions: Angioimmunoblastic T-cell Lymphoma|Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue|Nodal Marginal Zone B-cell Lymphoma|Recurrent Adult T-cell Leukemia/Lymphoma|Recurrent Grade 1 Follicular Lymphoma|Recurrent Grade 2 Follicular Lymphoma|Recurrent Marginal Zone Lymphoma|Recurrent Small Lymphocytic Lymphoma|Splenic Marginal Zone Lymphoma|Waldenström Macroglobulinemia
Interventions: DRUG: nelarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase II/III Study of Sargramostim
Status: COMPLETED
Conditions: COVID-19
Interventions: DRUG: Sargramostim|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of CoVid-19 (CoronaVirusDisease-19) and Exercise on Myocardial Fibrosis and Ventricular Arrhythmias
Status: COMPLETED
Conditions: Covid19|Athletes Heart|Myocarditis Viral|Ventricular Arrythmia
Interventions: OTHER: ILR implantation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Psychological Support Group and Its Effects on Mood, Anxiety and Coping
Status: ACTIVE_NOT_RECRUITING
Conditions: Coping Strategies|Anxiety|Nurse-Patient Relations|Psychological|Mood Depressed|Rehabilitation|Neurologic Manifestations
Interventions: DIAGNOSTIC_TEST: evalutaion scales
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Everolimus and Tacrolimus Combination for Regression of Left Ventricular Hypertrophy in Renal Transplants
Status: COMPLETED
Conditions: Hypertrophy, Left Ventricular
Interventions: DRUG: Everolimus|DRUG: Mycophenolate mofetil|DRUG: Tacrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: the Effect of a Red Rice Nutrition Supplement on Cholesterol Levels
Status: COMPLETED
Conditions: Cholesterol Level|HDL Level|LDL Level|TG Level
Interventions: DIETARY_SUPPLEMENT: red rice supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Individually Marked Panretinal lasEr phoTokoagUlation for Proliferative Diabetic Retinopathy Study - DETECT
Status: COMPLETED
Conditions: Proliferative Diabetic Retinopathy
Interventions: PROCEDURE: Panretinal laser photocoagulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SpyGlass Versus ESWL for Large Common Bile Duct Stones
Status: COMPLETED
Conditions: Choledocholithiasis|Common Bile Duct Calculi
Interventions: PROCEDURE: ERCP+ SpyGlass|PROCEDURE: ESWL+ ERCP
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Unilateral vs Bilateral Application of Muscle Energy Techniques in Pelvic Somatic Dysfunction
Status: NOT_YET_RECRUITING
Conditions: Pelvic Somatic Dysfunction
Interventions: OTHER: Osteopathic Treatment Technique- Muscle Energy Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of Mizoribine in the Treatment of Lupus Nephritis
Status: COMPLETED
Conditions: Lupus Nephritis
Interventions: DRUG: Mizoribine (MZR)|DRUG: Cyclophosphamide (CTX)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety, Tolerability and Efficacy of XEN1101 in Major Depressive Disorder
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: XEN1101 10 mg|DRUG: XEN1101 20 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Ozonated Oil on Healing of Palatal Area.
Status: NOT_YET_RECRUITING
Conditions: Healing Surgical Wounds
Interventions: PROCEDURE: ozonated oil|PROCEDURE: non ozonated oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Volumetric Specimen Imager Device for the Intraoperative Imaging of Patients With Breast Carcinoma and Breast Ductal Carcinoma In Situ, The VIVID Study
Status: RECRUITING
Conditions: Anatomic Stage 0 Breast Cancer AJCC v8|Bilateral Breast Carcinoma|Breast Ductal Carcinoma In Situ|Invasive Breast Carcinoma|Multicentric Breast Carcinoma|Prognostic Stage 0 Breast Cancer AJCC v8
Interventions: PROCEDURE: Intraoperative Imaging|DEVICE: Lumpectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Testing New Marketing Models for Improved Cookstoves - Uganda
Status: COMPLETED
Conditions: Air Pollution, Indoor|Behavior
Interventions: OTHER: RCT 1- Testing the Effectiveness of Marketing Messages in Increasing Willingness to Pay|OTHER: RCT 3-Measure the Effects of Fuel Efficient Cookstoves on Health, Fuel Use and Time Spent Collecting Fuel|OTHER: RCT 2- Testing the Effectiveness of the Novel Sales Offer and its ability to Increase Uptake of Purchasing Energy Efficient Cookstoves
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Refractory Schizophrenia With Riluzole
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective
Interventions: DRUG: Riluzole|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Prediction of Clinical Response to SSRI Treatment in Bipolar Disorder Using Serotonin 1A Receptor PET Imaging
Status: COMPLETED
Conditions: Bipolar Disorder
Interventions: DRUG: Fluoxetine|DRUG: Citalopram
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: LDCT-SC-FI Low-dose CT Screening for Lung Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Lung Cancer Screening
Interventions: DEVICE: Smoking cessation mobile application|BEHAVIORAL: Written material for smoking cessation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Phase 3 Study - Safety and Efficacy of PTK 0796 in Patients With Complicated Skin and Skin Structure Infection (CSSSI)
Status: WITHDRAWN
Conditions: Skin Structures and Soft Tissue Infections
Interventions: DRUG: PTK 0796|DRUG: Linezolid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vitamin D and Pregnancy Outcome in PCOS Patients
Status: UNKNOWN
Conditions: Polycystic Ovary Syndrome|in Vitro Fertilization
Interventions: DRUG: vitamin D|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Gabapentin vs. Placebo for Adjuvant Pain Control Following Acute Rib Fractures
Status: COMPLETED
Conditions: Acute Pain
Interventions: DRUG: Gabapentin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Web-based Smoking Cessation Intervention: Transition From Inpatient to Outpatient
Status: COMPLETED
Conditions: Cigarette Smoking|Home Access to Internet and Email|Cognitively and Physically Able to Participate|English Speaking and Reading
Interventions: BEHAVIORAL: Web-based smoking cessation program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Tolerability, Pharmacokinetics, and Pharmacodynamics of INS50589 Intravenous Infusion in Healthy Volunteers
Status: COMPLETED
Conditions: Cardiovascular Disease
Interventions: DRUG: INS50589 Intravenous Infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Study of LY900014 in Participants With Type 1 Diabetes on Insulin Injection Therapy
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: DRUG: LY900014|DRUG: Insulin Lispro
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Early Versus Late DC-cardioversion of Persistent Atrial Fibrillation. Effect on Atrial Remodeling,Inflammatory and Neurohumoral Markers and Recurrence of Atrial Fibrillation
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DRUG: Pradaxa|PROCEDURE: TEE|OTHER: Compare TEE guided cardioversion to Dabigatran + DC cardioversion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Post-Marketing Surveillance of Dehydrated Human Amnion/Chorion Membrane (DHACM) in Non-Ischemic Chronic Wounds
Status: RECRUITING
Conditions: Diabetic Foot Ulcer|Venous Leg Ulcer
Interventions: DEVICE: EPIFIX
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trauma and Truth Interventions (NET) Versus Conflict Resolution and Social Skills Trainings for Vulnerable Youths in Northern Uganda
Status: COMPLETED
Conditions: PTSD|Depression|Aggression
Interventions: BEHAVIORAL: NET Truth Education|BEHAVIORAL: Conflict Resolution and Social Competence Skills|BEHAVIORAL: Traditional Ways of Coping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Actions to Decrease Disparities in Risk and Engage in Shared Support for Blood Pressure Control (ADDRESS-BP) in Blacks
Status: NOT_YET_RECRUITING
Conditions: Hypertension (HTN)
Interventions: OTHER: Practice support And Community Engagement (PACE)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Lisdexamfetamine Dimesylate (LDX) Pilot Cognition Study to Evaluate the Utility of a Standardized Battery of Tests in Adults With Attention-Deficit Hyperactivity Disorder (ADHD)
Status: COMPLETED
Conditions: Attention-Deficit Hyperactivity Disorder
Interventions: DRUG: Lisdexamfetamine Dimesylate (LDX)|DRUG: Immediate Release Mixed Amphetamine Salts (MAS-IR)|DRUG: LDX Placebo + MAS-IR Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Study of Obeldesivir to Treat Nonhospitalized Adults With Acute Respiratory Syncytial Virus (RSV) Infection
Status: NOT_YET_RECRUITING
Conditions: RSV Infection
Interventions: DRUG: Obeldesivir|DRUG: Obeldesivir Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Hepatic Artery Injection of Autologous Human Bone Marrow-Derived MSCs in Patients With Alcoholic LC
Status: UNKNOWN
Conditions: Alcoholic Liver Cirrhosis
Interventions: BIOLOGICAL: Cellgram™ (Bone marrow-derived MSCs)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT