pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Treatment of Non-Gestational Acute Uterine Bleeding: A Randomized Trial
Status: COMPLETED
Conditions: Uterine Hemorrhage|Menorrhagia
Interventions: DRUG: Provera|DRUG: Combination Birth Control pills
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase IV Study in Asthma Subjects for Dry Powder Inhaler (DPI) Versus (vs) Metered Dose Inhaler (MDI) Correct Use
Status: COMPLETED
Conditions: Asthma
Interventions: DEVICE: ELLIPTA DPI|DEVICE: GSK MDI|DEVICE: AZ MDI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CT Perfusion Imaging in Predicting Treatment Response in Patients With Non-small Cell Lung Cancer or Lung Metastases Treated With Stereotactic Ablative Radiation Therapy
Status: COMPLETED
Conditions: Malignant Lung Neoplasm|Metastatic Malignant Neoplasm in the Lung|Non-Small Cell Lung Carcinoma|Stage IV Lung Cancer
Interventions: DEVICE: CAPP-Seq|DRUG: Isovue-200|RADIATION: Computed Tomography Perfusion Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Acetylsalicylic Acid and Eflornithine in Treating Patients at High Risk for Colorectal Cancer
Status: COMPLETED
Conditions: Adenomatous Polyp
Interventions: DRUG: Aspirin|DRUG: Eflornithine|OTHER: Laboratory Biomarker Analysis|OTHER: Placebo|OTHER: Telephone-Based Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Effects of a Novel Probiotic on Gastrointestinal Health in Generally Healthy Adults
Status: COMPLETED
Conditions: Gastrointestinal Health|Immune Health|Digestive Health
Interventions: DIETARY_SUPPLEMENT: Probiotic|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Ultrasound Guided QLB III Versus Intrathecal Morphine for Analgesia After Cesarean Section
Status: COMPLETED
Conditions: Block
Interventions: DRUG: Morphine|DRUG: Quadratus lumborum block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Validation of the REMINDER Dementia Risk Reduction Program
Status: RECRUITING
Conditions: Healthy Aging|Risk Reduction|Old Age; Dementia
Interventions: BEHAVIORAL: REMINDER|BEHAVIORAL: Brain health Psychoeducation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Relative Bioavailability Study of Finasteride 5 mg Tablets Under Fasting Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Finasteride 5 mg Tablet, single dose|DRUG: Proscar® 5 mg Tablet, single dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Accelerated Tooth Movement With AcceleDent® and Aligners - a Pilot Project
Status: COMPLETED
Conditions: Tooth Movement|Malocclusion
Interventions: DEVICE: AcceleDent, Vibrational Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Enhanced Recovery Strategies in Elective Breast Surgery
Status: TERMINATED
Conditions: Pain, Acute|Nausea|Vomiting, Postoperative|Opioid Use|Satisfaction
Interventions: PROCEDURE: Paravertebral block procedure using either local anesthetic (0.25% bupivacaine) or sterile saline|OTHER: Enhanced recovery after breast surgery (ERABS) strategies|PROCEDURE: Sham paravertebral block using saline|DRUG: Paravertebral block using local anesthetic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study in Healthy Men That Tests if Taking BI 1265162 by Mouth, Intravenously, or Inhaled Influences the Amount of BI 1265162 in the Blood
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BI 1265162 (T1)|DRUG: BI 1265162 (T2)|DRUG: BI 1265162 (R)|DRUG: BI 1265162 (T3)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SPI-guided Analgesia During FESS for Intraoperative Blood Loss
Status: UNKNOWN
Conditions: Endoscopic Sinus Surgery
Interventions: DRUG: Remifentanil|DEVICE: surgical pleth index
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Neoadjuvant Therapy With Toripalimab and JS004 Combined With Platinum-based Doublet Chemotherapy for Resectable or Potentially Resectable Stage III Non-small Cell Lung Cancer: A Randomised Controlled, Open-label, Phase 2 Trial
Status: NOT_YET_RECRUITING
Conditions: Stage III Non-small Cell Lung Cancer
Interventions: DRUG: Toripalimab|DRUG: JS004|DRUG: Pemetrexed|DRUG: Nab-paclitaxel|DRUG: Carboplatin|PROCEDURE: Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 68Ga/177Lu-PSMA Theranostics in Recurrent Grade 3 and Grade 4 Glioma
Status: RECRUITING
Conditions: High Grade Glioma
Interventions: RADIATION: 177Lu-PSMA I&T
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High-flow Oxygen for Vaso-occlusive Pain Crisis
Status: UNKNOWN
Conditions: Sickle Cell Disease
Interventions: DEVICE: Stadard low-flow oxygen|DEVICE: HFNO with low FiO2 (21%-30%)|DEVICE: HFNO with intermediate FiO2 (50%)|DEVICE: HFNO with high FiO2 (100%)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Longitudinal Assessment of Cartilage Injury and Remodeling After Anterior Cruciate Ligament Rupture and Reconstruction:
Status: TERMINATED
Conditions: ACL - Anterior Cruciate Ligament Rupture|ACL Injury|Healthy
Interventions: PROCEDURE: Anterior cruciate ligament reconstruction
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Interest of ß 1-3 D Glucan Assays in Screening for the Onset of Invasive Aspergillosis in Neutropenic Patients With Acute Leukaemia.
Status: COMPLETED
Conditions: Invasive Fungal Infections
Interventions: BIOLOGICAL: blood samples
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: A Study to Compare the Efficacy and Safety of Topical Administration of FMX-101 for Treatment of Moderate-to-Severe Acne
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: FMX-101, 4% minocycline foam|DRUG: Vehicle Foam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Terlipressin on Effect of Renal Function in Cirrhotic Patients With Acute Gastrointestinal Hemorrhage
Status: COMPLETED
Conditions: Variceal Hemorrhage|Cirrhosis, Liver|Kidney Injury
Interventions: DRUG: Terlipressin|DRUG: Somatostatin|DRUG: Octreotide
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Pharmacokinetic Study of DW6013 (FDC of Linagliptin and Metformin) in Healthy Adult Volunteers in Fed Condition
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: DW6013
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Argatroban in Ischemic Stroke With Early Deterioration (EASE)
Status: COMPLETED
Conditions: Acute Progressive Ischemic Stroke
Interventions: DRUG: Argatroban
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combined Electroencephalogram, Magnetic Resonance Imaging-Positron Emission Tomography of Dexmedetomidine Induced Sleep
Status: COMPLETED
Conditions: Dexmedetomidine Induced Sedation
Interventions: DRUG: dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A 52 Week Study To Assess The Use Of Bococizumab (PF-04950615; RN316) In Subjects With Heterozygous Familial Hypercholesterolemia
Status: COMPLETED
Conditions: Heterozygous Familial Hypercholesterolemia
Interventions: DRUG: Bococizumab (PF-04950615;RN316)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Long-Term Safety and Efficacy of Tegoprubart in Kidney Transplant Recipients
Status: ENROLLING_BY_INVITATION
Conditions: Kidney Transplant Rejection
Interventions: DRUG: AT-1501|DRUG: Tacrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Effectiveness of Psoriasis Treatments on Systemic Inflammation
Status: COMPLETED
Conditions: Psoriasis|Inflammation
Interventions: DRUG: Methotrexate|DRUG: Ustekinumab|DRUG: Etanercept|DRUG: Adalimumab|DRUG: Acitretin|OTHER: UVB Excimer Laser|OTHER: Narrowband UVB
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Vestibular Rehabilitation and Severe Traumatic Brain Injury
Status: COMPLETED
Conditions: Severe Traumatic Brain Injury|Gait Disorders, Neurologic
Interventions: OTHER: Vestibular Rehabilitation (VR)|OTHER: Conventional Neurorehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Restrictive Versus Conservative Fluid Therapy in Colorectal Surgery
Status: COMPLETED
Conditions: Fluid Therapy
Interventions: PROCEDURE: restrictive fluid strategy|PROCEDURE: conservative fluid strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of Encapsulated Cell Technology (ECT) Implant for Participants With Early Stage Retinitis Pigmentosa
Status: COMPLETED
Conditions: Retinitis Pigmentosa
Interventions: DRUG: NT-501|DRUG: NT-501
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ASCT in Combination With C-CAR088 for Treating Patients With Ultra High-risk Multiple Myeloma (MM)
Status: RECRUITING
Conditions: Multiple Myeloma
Interventions: PROCEDURE: Autologous hematopoietic stem cell transplantation|BIOLOGICAL: C-CAR088
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasound-based Blood-brain Barrier Opening and Albumin-bound Paclitaxel and Carboplatin for Recurrent Glioblastoma
Status: RECRUITING
Conditions: Glioblastoma|Gliosarcoma|GBM|Glioblastoma Multiforme|Glioblastoma, IDH-wildtype|Recurrent Glioblastoma
Interventions: DEVICE: Sonication for opening of blood-brain barrier|DRUG: Chemotherapy, albumin-bound paclitaxel|DRUG: Chemotherapy, carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High Flow Nasal Cannula Use in Infants With Bronchiolitis
Status: TERMINATED
Conditions: Bronchiolitis
Interventions: DEVICE: Airvo (TM, Fisher & Paykel Healthcare) - High flow oxygen therapy|DEVICE: MedKit Finland - Usual oxygen therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Characterization of Baseline Biomarker Variability in Participants With Hepatocellular Carcinoma (MK-0000-215)
Status: TERMINATED
Conditions: Hepatocellular Carcinoma
Interventions: PROCEDURE: MRI|PROCEDURE: Pathology|PROCEDURE: Blood Samples|PROCEDURE: Blood Samples
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Targeting Resistant Prostate Cancer With ATR and PARP Inhibition (TRAP Trial)
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Cancer
Interventions: DRUG: Olaparib|DRUG: AZD6738
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low Intensity Shock Wave Therapy (LI-ESWT) for Erectile Dysfunction in Post Radical Prostatectomy Patients Not Responding to PDE5 Inhibitors (LI-ESWT)
Status: UNKNOWN
Conditions: Erectile Dysfunction
Interventions: DEVICE: Omnispec model ED1000|DEVICE: Sham control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of Perioperative Docetaxel, Oxaliplatin, and 5-Fluorouracil (FLOT) in Gastroesophageal Adenocarcinoma
Status: COMPLETED
Conditions: Gastric Adenocarcinoma|Esophageal Adenocarcinoma
Interventions: DRUG: FLOT (5-fluorouracil, oxaliplatin, docetaxel)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Using Attention Training to Reduce Adolescents' Anxious Symptoms
Status: TERMINATED
Conditions: Attentional Bias|Anxiety
Interventions: BEHAVIORAL: Attentional Bias Modification (ABM) task|BEHAVIORAL: Control task
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: VitD3 Supplementation in Patients With Multiple Myeloma
Status: NOT_YET_RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: Lenalidomide|DRUG: Vitamin D - Intensified|DRUG: Vitamin D - Therapeutic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect on Cognitive Performance and Safety/Tolerability of SSR180711C in Mild Alzheimer's Disease
Status: TERMINATED
Conditions: Alzheimer's Disease
Interventions: DRUG: SSR180711C|DRUG: donepezil|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Negative-pressure Wound Therapy on Full-thickness Skin Grafts of the Lower Leg
Status: ACTIVE_NOT_RECRUITING
Conditions: Skin Tumor
Interventions: DEVICE: Negative pressure device|PROCEDURE: Conventional care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Amniotic Fluid Ischemia Modified Albumin as a Novel e Prenatal Diagnostic Marker for Down Syndrome
Status: COMPLETED
Conditions: Down Syndrome|Prenatal Stress|Cytokines
Interventions: PROCEDURE: amniosyntesis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Azithromycin for Preterm Pre-labor Rupture of Membranes
Status: COMPLETED
Conditions: Preterm Pre-labor Rupture of Membranes
Interventions: DRUG: Azithromycin|DRUG: Ampicillin|DRUG: Azithromycin|DRUG: Azithromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Rhinocort Aqua Versus Placebo and Fluticasone Propionate
Status: COMPLETED
Conditions: Seasonal Allergic Rhinitis
Interventions: DRUG: Budesonide|DRUG: Fluticasone propionate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Comparative Controlled Study of Analgesic, Antiasthenic and Anti-Anxiety Effects of Xenon in Patients With Parkinson's Disease
Status: UNKNOWN
Conditions: Parkinson Disease
Interventions: DRUG: NBTX-001|DRUG: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mesalamine 2 g Sachet for the Maintenance of Clinical and Endoscopic Remission in Ulcerative Colitis (UC)
Status: COMPLETED
Conditions: Ulcerative Colitis
Interventions: DRUG: Mesalamine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Epigenetic Effects of a Single Bout of Exercise on Cardiovascular Risk Factors and the Metabolome
Status: COMPLETED
Conditions: Obesity|Type 2 Diabetes|Cardiovascular Diseases|Acute Exercise
Interventions: BEHAVIORAL: Acute exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Nonmyeloablative Allogeneic Stem Cell Transplant Followed by Bortezomib in High-risk Multiple Myeloma Patients
Status: COMPLETED
Conditions: Multiple Myeloma|High-Risk Cancer
Interventions: DRUG: Bortezomib following nonmyeloablative allogeneic transplant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of System Suspended Robotic Lokomat Gait in Patients With Incomplete Spinal Cord Injury
Status: COMPLETED
Conditions: Spinal Cord Injury
Interventions: OTHER: Training sessions|DEVICE: Lokomat system (Hocoma AG Switzerland)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Iodine-131 Anti-B1 Antibody for Chronic Lymphocytic Leukemia
Status: UNKNOWN
Conditions: Chronic Lymphocytic Leukemia
Interventions: DRUG: Iodine-131 Anti-B1 Antibody
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of 13-Valent Pneumococcal Conjugate Vaccine (13vPnC) in HIV-Infected Subjects 6 Years of Age or Older Who Are Naive to Pneumococcal Vaccine
Status: COMPLETED
Conditions: HIV Infections|Pneumococcal Infections
Interventions: BIOLOGICAL: 13-valent Pneumococcal Conjugate Vaccine (13vPnC)|BIOLOGICAL: 23-valent Pneumococcal Polysaccharide Vaccine (23vPS)|PROCEDURE: Blood draw|PROCEDURE: Blood draw
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Varenicline for Gait and Balance Impairment in Parkinson Disease
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: DRUG: Varenicline|DRUG: Sugar pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Care of AcromioClavicular Arthropathy in Manual Medicine Versus Corticosteroid Infiltration (ACAM)
Status: ACTIVE_NOT_RECRUITING
Conditions: Acromioclavicular Arthropathy
Interventions: OTHER: Manual medicine|DRUG: Corticosteroids infiltration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Mother's Push at Cesarean Delivery Mother's PUSHING AT CS A RANDOMIZED CONTROLLED TRIAL
Status: COMPLETED
Conditions: Caesarean Section|Mother-Child Relations|Post Operative Pain|Postpartum Depression
Interventions: PROCEDURE: Mother's push during CS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SCREENING
Clinical trial: Optic Nerve Stimulation To Prevent Visual Deficits After Endoscopic Cranial Approaches
Status: NOT_YET_RECRUITING
Conditions: Optic Nerve Injuries|Sellar Tumor|Skull Base Neoplasms
Interventions: PROCEDURE: Optic Nerve Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Maxillary Versus Bi-Maxillary Posterior Segments Intrusion Adult Subjects With Skeletal Open Bite
Status: COMPLETED
Conditions: Dental Malocclusion
Interventions: PROCEDURE: Maxillary posterior dento-alveolar intrusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Single v Dual-Operator Ultrasound Technique for Peripheral Vascular Access in the Emergency Department
Status: UNKNOWN
Conditions: Patients With Difficult Vascular Access.
Interventions: PROCEDURE: Dual Operator Ultrasound Guided IV placement|PROCEDURE: Single Operator Ultrasound Guided IV placement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Durvalumab in Combination With Platinum and Etoposide for the First Line Treatment of Patients With Extensive-stage Small Cell Lung Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Extensive-stage Small Cell Lung Cancer
Interventions: DRUG: Durvalumab|DRUG: Cisplatin|DRUG: Carboplatin|DRUG: Etoposide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hsp90 Inhibitor STA-9090 in Treating Patients With Metastatic Hormone-Resistant Prostate Cancer Previously Treated With Docetaxel-Based Chemotherapy
Status: COMPLETED
Conditions: Adenocarcinoma of the Prostate|Hormone-resistant Prostate Cancer|Recurrent Prostate Cancer|Stage IV Prostate Cancer
Interventions: DRUG: Hsp90 inhibitor STA-9090|OTHER: laboratory biomarker analysis|GENETIC: polymerase chain reaction|OTHER: enzyme-linked immunosorbent assay|GENETIC: RNA analysis|OTHER: spectrophotometry|GENETIC: reverse transcriptase-polymerase chain reaction|GENETIC: gene expression analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multimodal Quantified Analysis of Facial Movements: Comparison Between Pathological and Control Subjects
Status: RECRUITING
Conditions: Electromyography|Eye-tracking|Facial Palsy
Interventions: OTHER: dental impressions|OTHER: Simultaneous MoCap and EMG acquisition|OTHER: Eye-tracking acquisition for pathological subjects|OTHER: Follow-up visit for pathological subjects
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Diagnosing Vesicoureteric Reflux in Children by Direct Isotope Cystography and Contrast Enhanced Voiding Ultrasonography
Status: RECRUITING
Conditions: VUR - Vesicoureteric Reflux
Interventions: DIAGNOSTIC_TEST: Contrast-enhanced voiding ultrasonography (CEVUS), Direct isotope cystography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Adrenocortical Functions in Women With Nonclassical 21-hydroxylase Deficiency.
Status: UNKNOWN
Conditions: Adrenal Hyperplasia, Congenital|21-hydroxylase Deficiency
Interventions: OTHER: Functional explorations|OTHER: Functional explorations
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluating Treatment of ADHD in Children With Down Syndrome
Status: RECRUITING
Conditions: Down Syndrome|ADHD
Interventions: DRUG: Quillivant XR|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Dipeptidyl Peptidase 4 Inhibition on Growth Hormone Secretion in Women With Polycystic Ovarian Syndrome
Status: COMPLETED
Conditions: Polycystic Ovary Syndrome
Interventions: DRUG: Sitagliptin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Decitabine in Treating Patients With Melanoma or Other Advanced Cancer
Status: COMPLETED
Conditions: Chronic Myeloproliferative Disorders|Leukemia|Lymphoma|Multiple Myeloma and Plasma Cell Neoplasm|Myelodysplastic Syndromes|Precancerous Condition|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: decitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Omadacycline Versus Linezolid for the Treatment of ABSSSI (EudraCT #2013-003644-23)
Status: COMPLETED
Conditions: Bacterial Infections|Skin Structures and Soft Tissue Infections
Interventions: DRUG: Omadacycline|DRUG: Linezolid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Efficacy and Safety of Vardenafil in Patients Erectile Dysfunction Solely Secondary to Spinal Cord Injury
Status: COMPLETED
Conditions: Erectile Dysfunction
Interventions: DRUG: Vardenafil (Levitra, BAY38-9456)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Neuropsychobiology of Brain Theta-burst Stimulation: A Mind-body Interface for Depression
Status: COMPLETED
Conditions: Depression|Treatment
Interventions: DEVICE: TBS|DEVICE: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Evaluation of Sugammadex in Cardiac Patients (19.4.309)(P05934)
Status: COMPLETED
Conditions: Anesthesia
Interventions: DRUG: Sugammadex|DRUG: Sugammadex|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transcranial Photobiomodulation for Reducing Autism Symptoms in Children - Open Label Study (TPBMASDOL)
Status: COMPLETED
Conditions: Autism Spectrum Disorder
Interventions: DEVICE: Cognilum TM: Light Treatment Condition
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ExAblate Transcranial MRgFUS for the Management of Treatment-Refractory Movement Disorders
Status: ACTIVE_NOT_RECRUITING
Conditions: Movement Disorders|Essential Tremor|Holmes Tremor|Parkinson's Disease|Wilson's Disease|Huntington's Disease|Dystonia|Tardive Dyskinesia|Orofacial Dyskinesias
Interventions: DEVICE: Transcranial ExAblate System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: FAAH Inhibitor Trial for Adults With Tourette Syndrome
Status: TERMINATED
Conditions: Tourette Syndrome
Interventions: DRUG: PF-04457845|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pembrolizumab Alone or With Idelalisib or Ibrutinib in Treating Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia or Other Low-Grade B-Cell Non-Hodgkin Lymphomas
Status: COMPLETED
Conditions: Recurrent B-Cell Non-Hodgkin Lymphoma|Recurrent Chronic Lymphocytic Leukemia|Recurrent Extranodal Marginal Zone Lymphoma of Mucosa-Associated Lymphoid Tissue|Recurrent Grade 1 Follicular Lymphoma|Recurrent Grade 2 Follicular Lymphoma|Recurrent Grade 3 Follicular Lymphoma|Recurrent Lymphoplasmacytic Lymphoma|Recurrent Marginal Zone Lymphoma|Recurrent Nodal Marginal Zone Lymphoma|Recurrent Small Lymphocytic Lymphoma|Recurrent Splenic Marginal Zone Lymphoma|Recurrent Waldenstrom Macroglobulinemia|Refractory B-Cell Non-Hodgkin Lymphoma|Refractory Chronic Lymphocytic Leukemia|Refractory Extranodal Marginal Zone Lymphoma of Mucosa-Associated Lymphoid Tissue|Refractory Follicular Lymphoma|Refractory Lymphoplasmacytic Lymphoma|Refractory Nodal Marginal Zone Lymphoma|Refractory Small Lymphocytic Lymphoma|Refractory Splenic Marginal Zone Lymphoma|Refractory Waldenstrom Macroglobulinemia|Richter Syndrome|Waldenstrom Macroglobulinemia
Interventions: DRUG: Ibrutinib|DRUG: Idelalisib|OTHER: Laboratory Biomarker Analysis|BIOLOGICAL: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Safety and Efficacy of Tobramycin for Inhalation in Young Children With Cystic Fibrosis
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: Tobramycin for Inhalation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Safety, PK and Immunomodulatory Effects of AB103 in Necrotizing Soft Tissue Infections Patients
Status: COMPLETED
Conditions: Necrotizing Soft Tissue Infections
Interventions: DRUG: AB103|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact Evaluation of a Targeted mHealth Intervention to Improve Uptake of Postpartum Contraception in Kenya
Status: RECRUITING
Conditions: Postpartum Family Planning
Interventions: BEHAVIORAL: PROMPTS Enhanced Family Planning Counselling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety, Tolerability, and Pharmacokinetic/Pharmacodynamic Study of KW-2449 in Acute Myelogenous Leukemia (AML) (Protocol Number: 2449-US-002)
Status: TERMINATED
Conditions: Acute Myelogenous Leukemia (AML)
Interventions: DRUG: KW-2449
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Prospective, Open-label, Non-randomized, Clinical Trial to Determine if Natalizumab (Tysabri®) Improves Ambulatory Measures in Relapsing-remitting Multiple Sclerosis (RRMS) Patients
Status: COMPLETED
Conditions: Relapsing Remitting Multiple Sclerosis (RRMS)
Interventions: DRUG: BG00002 (natalizumab)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics and Safety of Vilaprisan in Renal Impairment
Status: COMPLETED
Conditions: Uterine Fibroids|Endometriosis
Interventions: DRUG: Vilaprisan (BAY1002670)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: hands4health: A Multi-component Intervention on Hand Hygiene in Primary Health Care Facilities in Burkina Faso and Mali
Status: ACTIVE_NOT_RECRUITING
Conditions: Hand Hygiene Behavior|Hand Hygiene Effectiveness
Interventions: OTHER: Multi-component hand hygiene intervention in primary health care facilities
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Pembrolizumab and Induction Chemotherapy in Head and Neck Squamous Cell Carcinoma (PICH Study)
Status: WITHDRAWN
Conditions: Head and Neck Squamous Cell Carcinoma (HNSCC)
Interventions: DRUG: TPF2|OTHER: Radiotherapy with carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vitamins in Nitrous Oxide Study
Status: COMPLETED
Conditions: Major Surgery|Coronary Artery Disease
Interventions: DRUG: Vitamin B12 and folic acid|DRUG: Nitrous oxide and placebo|OTHER: standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: IntensVIH: Impact Of Therapy Intensification By An Integrase Inhibitor +/- CCR5 Inhibitor On The Lymphoid Reservoir For Hiv-1 In Chronically Infected Patients
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Isentress®|DRUG: Celsentri®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of PA9159 Nasal Spray for the Treatment of Seasonal Allergic Rhinitis
Status: COMPLETED
Conditions: Allergic Rhinitis
Interventions: DRUG: PA9159 nasal spray solution, 10 μg once daily for 14 days|DRUG: PA9159 nasal spray solution, 20 μg once daily for 14 days|DRUG: PA9159 nasal spray solution, 40 μg once daily for 14 days|DRUG: Placebo nasal spray solution without PA9159, once daily for 14 days
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Avelumab in Combination With Lenvatinib for Children With Primary CNS Tumors
Status: RECRUITING
Conditions: Central Nervous System Tumors
Interventions: DRUG: Avelumab|DRUG: Lenvatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Electrostimulation on Glucose Profile of Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes|Physical Activity
Interventions: DEVICE: electrostimulation (with Compex® Compex2* (DJO, Vista, CA, USA)) 3 days per week .|DEVICE: electrostimulation (with Compex® Compex2* (DJO, Vista, CA, USA)) 5 days per week
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RAPA-201 T Cell Therapy for Relapsed, Refractory Multiple Myeloma
Status: UNKNOWN
Conditions: Relapsed, Refractory Multiple Myeloma
Interventions: BIOLOGICAL: RAPA-201 Autologous T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multiple-loading Dose Regimen Study in Patients With Chronic Plaque-type Psoriasis
Status: COMPLETED
Conditions: Chronic Plaque Psoriasis
Interventions: DRUG: AIN457|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Rifamycin in Minimal Hepatic Encephalopathy
Status: COMPLETED
Conditions: Hepatic Encephalopathy|Cirrhosis, Liver
Interventions: DRUG: Rifamycin SV MMX|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Growth-promoting and Metabolic Effects of Growth Hormone (rhGH)
Status: TERMINATED
Conditions: Small for Gestational Age
Interventions: DRUG: rhGH (Norditropine SimpleXx®)|DRUG: rhGH norditropine simple Xx
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Characterization and Functionality of Calcium Channels Cav1.4 of Th17 Lymphocytes in Human With Psoriasis
Status: COMPLETED
Conditions: Psoriasis
Interventions: BIOLOGICAL: Skin biopsies|BIOLOGICAL: Blood sample
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Target Controlled Infusion of Etomidate or Propofol for Anesthesia of Thoracoscopic Mitral Valve Replacement Surgery
Status: UNKNOWN
Conditions: Delirium|Hemodynamic Instability
Interventions: DRUG: Propofol|DRUG: Etomidate|DEVICE: Bispectral Index Monitor|DRUG: Induction of anesthesia|DRUG: Maintenance of anesthesia|OTHER: Tracheal Intubation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Translocator Protein and Inflammation After Traumatic Brain Injury
Status: COMPLETED
Conditions: Traumatic Brain Injury (TBI)|Healthy
Interventions: DRUG: [11C]PBR28 and Positron Emission Tomography (PET)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparison of Navicular Mobilization and Rigid Tape in Pes Planus
Status: COMPLETED
Conditions: Pes Planus
Interventions: OTHER: navicular mobilization|OTHER: rigid tapping|OTHER: Navicular Mobilization and Rigid Taping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study to Evaluate Efficacy and Safety of Dovitinib (TKI258) in Advanced Scirrhous Gastric Carcinoma Patients
Status: COMPLETED
Conditions: Adenocarcinoma, Scirrhous|Linitis Plastica|Stomach Neoplasms|Stomach Diseases|Neoplasms by Site|Neoplasms
Interventions: DRUG: TKI258
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Florida Cerebrovascular Disease Biorepository and Genomics Center
Status: RECRUITING
Conditions: Cerebrovascular Disease|Ischemic Stroke|Transient Ischemic Attack|Intracerebral Hemorrhage|Aneurysmal Subarachnoid Hemorrhage|Vascular Dementia|Anoxic Brain Injury|Unruptured Intracranial Aneurysm|Carotid Artery Stenosis Symptomatic|Asymptomatic Carotid Artery Stenosis|Non-Aneurysmal Perimesencephalic Subarachnoid Haemorrhage|Cerebral Venous Thrombosis|Moyamoya Disease|Fibromuscular Dysplasia|Subarachnoid Hemorrhage|Leukoaraiosis|Arteriovenous Fistula|Reversible Cerebral Vasoconstriction Syndrome|CADASIL
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy of Ursodeoxycholic Acid (UDCA) in Patients With Type 2 Diabetes
Status: UNKNOWN
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: UDCA (Ursodeoxycholic acid)|DRUG: Placebo|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Interchangeability of Two Inactivated Hepatitis A Vaccines
Status: COMPLETED
Conditions: Hepatitis A
Interventions: BIOLOGICAL: Healive+Healive|BIOLOGICAL: Healive+Havrix|BIOLOGICAL: Havrix+Havrix|BIOLOGICAL: Havrix+Healive
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of St. John´s Wort/Valerian Extract Versus Placebo in Children and Adolescents With ADHD
Status: COMPLETED
Conditions: ADHD
Interventions: DRUG: Sedariston|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Lean Beef Consumption and Insulin Sensitivity in Men and Women With Risk Factors for Diabetes
Status: COMPLETED
Conditions: Metabolic Syndrome|PreDiabetes
Interventions: OTHER: USDA Style Diet|OTHER: Lean Beef Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Oral and Long-Acting Injectable Cabotegravir and Rilpivirine in Virologically Suppressed Children Living With HIV-1, Two to Less Than 12 Years of Age
Status: RECRUITING
Conditions: HIV-1-infection
Interventions: DRUG: Once daily CAB tablet + RPV tablet|DRUG: Long acting CAB injectable + long acting RPV injectable|DRUG: Long acting CAB injectable + long acting RPV injectable
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of a New Chewable Versus the Swallowable Tablet of Mebendazole Against Hookworm
Status: COMPLETED
Conditions: Hookworm Infections
Interventions: DRUG: Mebendazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MSB11022 in Moderate to Severe Chronic Plaque Psoriasis
Status: COMPLETED
Conditions: Psoriasis|Plaque Type Psoriasis|Moderate to Severe Plaque Psoriasis
Interventions: DRUG: MSB11022|DRUG: Humira®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Mircera for the Maintenance Treatment of Participants With Chronic Renal Anemia
Status: COMPLETED
Conditions: Chronic Renal Anemia
Interventions: DRUG: Methoxy polyethylene glycol-epoetin beta
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Elsamitrucin (SPP 28090) in Patients With Relapsed or Refractory Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Non-Hodgkin's Lymphoma
Interventions: DRUG: Elsamitrusin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Evaluate the Efficacy and Safety of YVOIRE® Contour Compared With Restylane SubQ™ Injected Into the Anteromedial Malar Region
Status: UNKNOWN
Conditions: Normal, Healthy Adults With Moderate, Severe, or Very Severe Volume Loss of Anteromedial Malar Region
Interventions: DEVICE: YVOIRE® contour|DEVICE: Restylane SubQ™
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Non-invasive Phrenic Nerve Stimulation in ARDS Patient
Status: RECRUITING
Conditions: ARDS, Human|Ventilator-Induced Lung Injury|Diaphragm Injury
Interventions: DEVICE: PNS group
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Seasonal Malaria Vaccination (RTS,S/AS01) and Seasonal Malaria Chemoprevention (SP/AQ) Extension Study
Status: COMPLETED
Conditions: Malaria,Falciparum|Child, Only
Interventions: BIOLOGICAL: Tetanus/diphtheria toxoids|DRUG: SMC with SP+AQ|BIOLOGICAL: RTS,S/AS01|DRUG: SMC placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Oncological and Perioperative Outcomes of Laparoscopic Versus Robotic Partial Nephrectomy for Treatment of Renal Tumors.
Status: RECRUITING
Conditions: Renal Cell Carcinoma
Interventions: PROCEDURE: laparoscopic partial nephrectomy|PROCEDURE: robotic partial nephrectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TNF-Bound Colloidal Gold in Treating Patients With Advanced Solid Tumors
Status: COMPLETED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: BIOLOGICAL: colloidal gold-bound tumor necrosis factor|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multiple Ascending Dose Study of GLPG0974 in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: GLPG0974|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessing Efficacy of Intravenous Acetaminophen for Perioperative Pain Control for Oocyte Retrieval
Status: COMPLETED
Conditions: Infertility, Female|Pain, Postoperative
Interventions: DRUG: IV Acetaminophen|DRUG: PO Acetaminophen|OTHER: Placebo IV Acetaminophen|OTHER: Placebo PO Acetaminophen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Intraoperative GDFT on the Postoperative Brain Edema
Status: COMPLETED
Conditions: Fluid Therapy|Brain Edema|Brain Tumor
Interventions: OTHER: GDFT|OTHER: traditional fluid therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Trial to Evaluate the Safety of Long Term Treatment With Nintedanib in Patients With Scleroderma Related Lung Fibrosis
Status: COMPLETED
Conditions: Lung Diseases, Interstitial
Interventions: DRUG: Nintedanib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Low-dose Intracoronary Reteplase on Myocardial Infarct Size During Primary Percutaneous Coronary Intervention
Status: TERMINATED
Conditions: Acute ST-segment Elevation Myocardial Infarction
Interventions: DRUG: Normal Saline|DRUG: Reteplase Injection 9mg|DRUG: Reteplase Injection 18mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Preoperative and Postoperative Oral Nutritional Supplements in Malnourished Post-gastrectomy Patients
Status: COMPLETED
Conditions: Malnourished|Stomach Neoplasms|Gastrointestinal Stromal Tumors
Interventions: DIETARY_SUPPLEMENT: Ensure powder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Surgery and/or Chemotherapy in Treating Children With Infantile, Congenital, or Childhood Fibrosarcoma
Status: TERMINATED
Conditions: Sarcoma
Interventions: BIOLOGICAL: dactinomycin|DRUG: cyclophosphamide|DRUG: etoposide|DRUG: ifosfamide|DRUG: vincristine sulfate|PROCEDURE: Conventional Surgery|BIOLOGICAL: MESNA (mercaptoethane sulfonate)|BIOLOGICAL: Filgrastim
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT