pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: To Demonstrate the Relative Bioavailability of Cyclobenzaprine HCl Tablets
Status: COMPLETED
Conditions: Depression
Interventions: DRUG: Cyclobenzaprine HCl Tablets 10 mg, Cord Laboratories|DRUG: Cyclobenzaprine HCl Tablets 10 mg, Merck Sharp & Dohme
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Efficacy and Safety of Wishbone HA as Bone Graft Substitute, a Pre-market Clinical Investigation
Status: UNKNOWN
Conditions: Bone Loss in Jaw
Interventions: DEVICE: Bone graft substitute
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adolescents as Change Agents in the Incorporation of a Parental Component for a School Based Prevention Program
Status: UNKNOWN
Conditions: Primary Prevention
Interventions: BEHAVIORAL: Prevention Program "young In Favor of Myself", active parents|BEHAVIORAL: Prevention Program "young In Favor of Myself", no parental involvement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: N-3 PUFA and Rheumatoid Arthritis in Korea
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DIETARY_SUPPLEMENT: Omega-3 fatty acid|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Physical Fitness/Training and Inflammatory Immune Responses in Patients With End-stage Renal Disease
Status: RECRUITING
Conditions: End-stage Renal Disease
Interventions: OTHER: aerobic training by a cycle ergometer and Biodex system 4 pro
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Airtraq in Class 2-3 Obese and Nonobese Men During Intubation: a Prospective Randomized Clinical Study
Status: NOT_YET_RECRUITING
Conditions: Obesity, Morbid|Intubation; Difficult or Failed|Video Laryngoscope|Men
Interventions: DEVICE: airtraq video laryngoscope
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: ANIMATE: Phase II Study of Nivolumab Monotherapy for Relapsed/Refractory Hodgkin Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Hodgkin Lymphoma
Interventions: DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare the Efficacy and Safety of FK506MR vs Prograf® in Patients Undergoing Kidney Transplantation
Status: COMPLETED
Conditions: Kidney Transplantation
Interventions: DRUG: FK506MR|DRUG: Prograf|DRUG: Mycophenolate Mofetil|DRUG: Methylprednisolone|DRUG: Prednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Cardiac Autonomic Control System Response to Vestibular Stimulation in Subjects With and Without BPPV
Status: COMPLETED
Conditions: Benign Paroxysmal Positional Vertigo|Vertigo|Autonomic Nervous System
Interventions: DIAGNOSTIC_TEST: Heart rate variability parameters monitoring
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of Olezarsen (ISIS 678354) Administered to Participants With Severe Hypertriglyceridemia
Status: ACTIVE_NOT_RECRUITING
Conditions: Severe Hypertriglyceridemia
Interventions: DRUG: Olezarsen|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study in Healthy Men to Test Whether Rifampicin Influences the Amount of BI 894416 in the Blood
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BI 894416|DRUG: Rifampicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lignocaine Versus Sodium Bicarbonate on Reducing Pain During Propofol Injection
Status: COMPLETED
Conditions: Propofol Adverse Reaction
Interventions: DRUG: Propofol Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Safety of Cultured Allogeneic Adult Umbilical Cord Derived Mesenchymal Stem Cell Intravenous Infusion for CP
Status: RECRUITING
Conditions: Cerebral Palsy
Interventions: BIOLOGICAL: AlloRx
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized Prospective Trial of Total Knee Arthroplasty Options Comparing Standard Knee Cutting Guides and MRI Generated Patient Specific Custom Cutting Guides
Status: COMPLETED
Conditions: Osteoarthritis of the Knee
Interventions: OTHER: Instrument
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Primary Dynamization Versus Standard Interlocking Intramedullary Nail in Treatment of Tibial Shaft Fractures in Adults
Status: RECRUITING
Conditions: Tibial Shaft Fractures
Interventions: PROCEDURE: interlocking intramedullary tibial nail
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination of Tislelizumab and Chemoradiotherapy in Esophageal Cancer (EC-CRT-002)
Status: RECRUITING
Conditions: Esophageal Squamous Cell Carcinoma|Locally Advanced Esophageal Squamous Cell Carcinoma
Interventions: DRUG: Paclitaxel, Cisplatin|DRUG: tislelizumab|RADIATION: Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasound-Monitored Changes in Achilles Tendinopathy After Extracorporeal Shock Wave Therapy
Status: COMPLETED
Conditions: Achilles Tendinopathy
Interventions: DEVICE: BTL-6000 FSWT|DEVICE: BTL-6000 FSWT with sham applicator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Cephalic Spread of Block With Head Down Tilt in Spinal Anaesthesia - A Randomised Controlled Study
Status: COMPLETED
Conditions: Head-Down Tilt Following Spinal Anesthesia
Interventions: PROCEDURE: Group X - head low tilt|PROCEDURE: Group Y - head low tilt|PROCEDURE: Group C - neutral
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: RCT of the Naturopathic Anti-Inflammatory Diet
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Prediabetes
Interventions: BEHAVIORAL: Diet (Anti-Inflammatory or standard diabetic diet)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Emerfetamab (AMG 673) in Adults With Relapsed/Refractory Acute Myeloid Leukemia (AML)
Status: TERMINATED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Emerfetamab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Suprazygomatic Maxillary Nerve Block in Cleft Palate Outcomes
Status: UNKNOWN
Conditions: Cleft Palate Children
Interventions: PROCEDURE: Ultrasound-guided bilateral suprazygomatic maxillary nerve block|PROCEDURE: Local anesthetic infiltration of the palate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Design and Development of a Novel Food Supplement for Osteoporosis Based on Gut Microbiome Mechanisms
Status: COMPLETED
Conditions: Osteopenia|Postmenopausal Osteopenia
Interventions: DIETARY_SUPPLEMENT: Calcium and vitamin D supplement|DIETARY_SUPPLEMENT: Calcium, vitamin D and prebiotic supplement|DIETARY_SUPPLEMENT: Calcium, vitamin D and flavonoid supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Neoadjuvant Chemotherapy of Nimotuzumab Plus Nab-Paclitaxel in Squamous Cell Carcinoma of Esophagus
Status: WITHDRAWN
Conditions: Squamous Cell Carcinoma of Esophagus
Interventions: DRUG: Nimotuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vaccine Therapy Plus QS21 in Treating Patients With Progressive Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: BIOLOGICAL: QS21|BIOLOGICAL: TF(c)-KLH conjugate vaccine|BIOLOGICAL: Thomsen-Friedenreich antigen|BIOLOGICAL: keyhole limpet hemocyanin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Investigating the Safety, Tolerability, and Efficacy of Elamipretide Topical Ophthalmic Solution for Treatment of Leber's Hereditary Optic Neuropathy
Status: COMPLETED
Conditions: Leber's Hereditary Optic Neuropathy
Interventions: DRUG: elamipretide (MTP-131) 1% topical ophthalmic solution|DRUG: Vehicle topical ophthalmic solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Biomarkers in Repetitive Transcranial Magnetic Stimulation (rTMS) for Adolescent Depression
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DEVICE: NeuroStar TMS Therapy® System|DEVICE: NeuroStar XPLOR®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: DURABILITY™ Iliac Study
Status: COMPLETED
Conditions: Peripheral Arterial Disease|Claudication
Interventions: DEVICE: Protégé® EverFlex™ Self-Expanding Stent System, and Protégé® GPS™ Self-Expanding Stent System.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Impact of a Health Video Game on User-Game Engagement and Dietary Choices
Status: COMPLETED
Conditions: Dietary Habits|Nutrition Knowledge
Interventions: BEHAVIORAL: fooya!™|OTHER: WordSearch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Overcoming Chemotherapy Resistance In Refractory Multiple Myeloma With Simvastatin and Zoledronic Acid
Status: TERMINATED
Conditions: Multiple Myeloma
Interventions: DRUG: Simvastatin and zoledronic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fentanyl Effect on Blood Pressure in Elderly Patients After Induction of General Anesthesia
Status: UNKNOWN
Conditions: Hypotension
Interventions: DRUG: Sodium chloride|DRUG: Fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility and Acceptability of a Novel Cognitive Behavioral Skills Mobile App for Pregnant and Postpartum Individuals
Status: RECRUITING
Conditions: Perinatal Anxiety|Perinatal Depression
Interventions: BEHAVIORAL: Experimental: Maya Perinatal Cognitive Behavioral Skills App
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Immune Suppression Treatment for People With Sickle Cell Disease or β-Thalassemia Who Are Going to Receive an Allogeneic Hematopoietic Cell Transplantation (HCT)
Status: RECRUITING
Conditions: Sickle Cell Disease|Thalassemia, Beta|Thalassemia
Interventions: DRUG: Fludarabine|DRUG: Cyclophosphamide|DRUG: Tacrolimus|DRUG: Mycophenolate Mofetil|BIOLOGICAL: Rabbit ATG|DRUG: Dexamethasone|DRUG: Bortezomib|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: the Effect of Reiki Application on Depression, Anxiety and Physical Activity in Patient With Multiple Sclerosis
Status: RECRUITING
Conditions: Multiple Sclerosis, Relapsing-Remitting
Interventions: BEHAVIORAL: Reiki
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of LY3295668 Erbumine in Participants With Relapsed/Refractory Neuroblastoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Neuroblastoma
Interventions: DRUG: LY3295668 Erbumine|DRUG: Topotecan|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Diastolic Function During the Transitional Period and Infancy Using Serial Echocardiography
Status: NOT_YET_RECRUITING
Conditions: Diastolic Dysfunction|Neonatal Encephalopathy|Small for Gestational Age at Delivery|Transient Tachypnea of the Newborn|Trisomy 21|Gestational Diabetes
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Interferon-alpha Lozenges for Prevention of Relapse in Hepatitis C
Status: COMPLETED
Conditions: Hepatitis C, Chronic
Interventions: DRUG: interferon-alpha lozenges|DRUG: placebo lozenges
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Genetic Analysis-Guided Irinotecan Hydrochloride Dosing of mFOLFIRINOX in Treating Patients With Locally Advanced Gastroesophageal or Stomach Cancer
Status: RECRUITING
Conditions: Esophageal Adenocarcinoma|Gastric Adenocarcinoma|Stage IIB Gastric Cancer|Stage IIIA Esophageal Adenocarcinoma|Stage IIIA Gastric Cancer|Stage IIIB Esophageal Adenocarcinoma|Stage IIIB Gastric Cancer|Stage IIIC Esophageal Adenocarcinoma|Stage IIIC Gastric Cancer
Interventions: DRUG: Oxaliplatin|DRUG: Leucovorin Calcium|DRUG: Irinotecan Hydrochloride|DRUG: Fluorouracil|PROCEDURE: Conventional Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Study of Different I-131 Doses in Graves' Disease
Status: UNKNOWN
Conditions: Graves' Disease
Interventions: DRUG: Low dose of I-131|DRUG: Intermediate dose|DRUG: High dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Respiratory and Hemodynamic Targets During General Anesthesia
Status: RECRUITING
Conditions: Patients Undergoing General Anesthesia
Interventions: PROCEDURE: Blood pressure|PROCEDURE: Positive end expiratory pressure|PROCEDURE: Tidal volume|PROCEDURE: Fraction of inspired oxygen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Hospice Advanced Dementia Symptom Management and Quality of Life Trial
Status: COMPLETED
Conditions: Dementia
Interventions: BEHAVIORAL: Dementia symptom management at home hospice edition|BEHAVIORAL: Education and Training
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Epsilon-Aminocaproaic Acid to Reduce the Need for Blood Transfusions During and Following Spine Surgery
Status: COMPLETED
Conditions: Scoliosis|Kyphosis|Lordosis|Spondylitis|Spinal Stenosis
Interventions: DRUG: Epsilon-Aminocaproic Acid (EACA)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Nebulized 3% Hypertonic Saline vs. Standard of Care in Patients With Bronchiolitis
Status: TERMINATED
Conditions: Bronchiolitis
Interventions: DRUG: 3% Nebulized Hypertonic Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of T-DXd for the Treatment of Solid Tumors Harboring HER2 Activating Mutations
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Solid Tumors With HER2 Mutation,eg:Colorectal,Urothelial,Gastric, Hepatobiliary,Endometrial,Melanoma,Ovarian,Cervical,Salivary Gland,Pancreatic,Breast
Interventions: DRUG: Trastuzumab deruxtecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Association of Gene Polymorphism With Susceptibility to T2DM and the Therapeutic Responses to Exenatide in Chinese Patients With T2DM
Status: RECRUITING
Conditions: Type 2 Diabetes Mellitus|Susceptibility, Genetic
Interventions: DRUG: GLP-1 receptor agonist|DRUG: responders group and nonresponders group
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Efficacy β-Alanine Supplementation in Performance Outcomes of Road Professional Endurance Cyclists
Status: COMPLETED
Conditions: Supplementation|Cyclists
Interventions: DIETARY_SUPPLEMENT: β-alanine|DIETARY_SUPPLEMENT: wheat semolina
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: HBM for Empowering Parental Toothbrushing and Sugar Intake Control
Status: UNKNOWN
Conditions: Health Behavior|Mobile Phone Use|Early Childhood Caries
Interventions: BEHAVIORAL: HBM-based text messages|BEHAVIORAL: Standard text message
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Immuno-inflammatory Profile and Response to Ischemic Stroke Reperfusion Therapies (IMMUNOSTROKE)
Status: NOT_YET_RECRUITING
Conditions: Stroke|Ischemic Stroke
Interventions: OTHER: Immuno-inflammatory profile description in patients with ischemic stroke
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Measuring Effects of Contact to Dogs
Status: COMPLETED
Conditions: Physiological Responses to Contact With Dogs|Psychological Responses to Contact With Dogs|Behavioural Responses to Contact With Dogs
Interventions: OTHER: Different intensities of contact to dogs
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Mesylate Apatinib Combined With Irinotecan in Treatment of Recurrent Small Cell Lung Cancer
Status: UNKNOWN
Conditions: Small Cell Lung Cancer
Interventions: DRUG: Apatinib|DRUG: Irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioavailability Study of (Buspar) Buspirone HCl Tablets Under Fasting Conditions
Status: COMPLETED
Conditions: To Determine Bioequivalence Under Fasting Conditions
Interventions: DRUG: buspirone HCl|DRUG: Buspar
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Colchicine for the Prevention of Vascular Events After an Acute Intracerebral Hemorrhage
Status: ACTIVE_NOT_RECRUITING
Conditions: Intracranial Hemorrhages
Interventions: DRUG: Colchicine Pill|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Impact of Disease Modifying Therapies (DMTs) and Associated Support Services in Relapsing Multiple Sclerosis (RMS) Patients
Status: COMPLETED
Conditions: Relapsing Multiple Sclerosis
Interventions: DRUG: Rebif|OTHER: Other: Disease modifying therapies (DMT)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Development of Three Dimensional Preoperative Planning System for the Osteosynthesis of Distal Humerus Fractures
Status: RECRUITING
Conditions: Distal Humerus Fracture
Interventions: DEVICE: Digital preoperative planning
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TACE With or Without Radiation Therapy in Treating Patients With Stage A-C Liver Cancer
Status: WITHDRAWN
Conditions: Adult Primary Hepatocellular Carcinoma|Recurrent Adult Primary Liver Cancer|Stage I Adult Primary Liver Cancer|Stage II Adult Primary Liver Cancer|Stage IIIA Adult Primary Liver Cancer
Interventions: PROCEDURE: transarterial chemoembolization|RADIATION: stereotactic radiosurgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Two Standard Therapies in the Management of Dementia With Agitation
Status: COMPLETED
Conditions: Senile Dementia, Alzheimer Type|Dementia, Alzheimer Type|Alzheimer Disease|Dementia
Interventions: DRUG: risperidone|DRUG: quetiapine|DRUG: olanzapine|DRUG: divalproex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Secondary Prophylaxis in Non-Hodgkin Lymphoma (NHL) and Chemotherapy-induced Thrombocytopenia
Status: COMPLETED
Conditions: Non-Hodgkin Lymphoma
Interventions: DRUG: Romiplostim
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Hepatitis B Surface Antigen(HBsAg) Loss in Chronic Hepatitis B Patients With Low Viral Load
Status: COMPLETED
Conditions: Chronic Hepatitis B
Interventions: DRUG: Peg-Interferon alfa 2a + Adefovir dipivoxil, Peg-Interferon alfa 2a + Tenofovir disoproxil fumarate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Respiratory Syncytial Virus (RSV)-Fusion (F) Protein Particle Vaccine
Status: COMPLETED
Conditions: Respiratory Syncytial Virus Infections
Interventions: BIOLOGICAL: RSV-F Particle Vaccine|BIOLOGICAL: RSV-F Particle Vaccine|BIOLOGICAL: RSV-F Particle Vaccine|BIOLOGICAL: RSV-F Particle Vaccine|BIOLOGICAL: Placebo|BIOLOGICAL: RSV-F Particle Vaccine|BIOLOGICAL: RSV-F Particle Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Nalmefene in Impulse Control Disorders in Parkinson's Disease: A Prospective Open Label Study
Status: UNKNOWN
Conditions: Impulse Control Disorders|Parkinson Disease
Interventions: DRUG: Nalmefene
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Patients With Diffuse Large B Cell Lymphoma Who Are Not Suitable for Anthracycline Containing Chemotherapy
Status: COMPLETED
Conditions: Diffuse Large B Cell Lymphoma
Interventions: DRUG: Cyclophosphamide|DRUG: Vincristine|DRUG: Prednisolone|DRUG: Rituximab|DRUG: Inotuzumab Ozogamicin|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tyrosine Kinase Inhibitor (TKI) + Anti-PD-1 Antibody in TKI-responded Microsatellite Stability/Proficient Mismatch Repair (MSS/pMMR) Metastatic Colorectal Adenocarcinoma.
Status: UNKNOWN
Conditions: MSS|pMMR|Metastatic Colorectal Adenocarcinoma
Interventions: DRUG: TKI ± anti-PD-1 antibody
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Full-fat Yogurt and Glucose Tolerance
Status: COMPLETED
Conditions: Pre-Diabetes
Interventions: DIETARY_SUPPLEMENT: Full-fat yogurt|DIETARY_SUPPLEMENT: Non-fat yogurt
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Nephrotoxicity of Iopamidol Versus Iodixanol in High-Risk Patients
Status: TERMINATED
Conditions: Chronic Renal Disease
Interventions: DRUG: Iopamidol injection 76%|DRUG: iodixanol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Nebulized Resveratrol Plus Carboxymethyl-β-Glucan for Reducing IL-5 in Children With Allergic Rhinitis
Status: COMPLETED
Conditions: Allergic Rhinitis
Interventions: DRUG: Resveratrol plus Carboxymethyl-β-Glucan|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Sirolimus in Complicated Vascular Anomalies
Status: UNKNOWN
Conditions: Kaposiform Hemangioendotheliomas|Tufted Angioma|Capillary Venous Lymphatic Malformation|Venous Lymphatic Malformation|Microcystic Lymphatic Malformation|Mucocutaneous Lymphangiomatosis and Thrombocytopenia|Capillary Lymphatic Arterial Venous Malformations|PTEN Overgrowth Syndrome With Vascular Anomaly|Lymphangiectasia Syndromes
Interventions: DRUG: sirolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sleep Loss and Glucose Metabolism in People With Family History of Type 2 Diabetes.
Status: COMPLETED
Conditions: Sleep|Sleep Deprivation|Insulin Resistance|Type 2 Diabetes
Interventions: OTHER: 5-hour bedtime|OTHER: 8.5-hour bedtimes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Whole Breast + Lymph Node Irradiation: Prone Compared to Supine Position in 15 or 5 Fractions
Status: COMPLETED
Conditions: Breast Neoplasms|Radiotherapy|Lymph Node Metastases
Interventions: DEVICE: Prone Radiotherapy|RADIATION: Acceleration|DEVICE: Supine Radiotherapy|RADIATION: Hypofractionation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Surgical Ablation of AF Efficacy Trial
Status: RECRUITING
Conditions: Atrial Fibrillation|Heart Failure
Interventions: PROCEDURE: Surgical Atrial Fibrillation Ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Manuka Honey Nano-Formulation in the Treatment of Acne Vulgaris
Status: NOT_YET_RECRUITING
Conditions: Acne Vulgaris
Interventions: OTHER: Manuka honey( MgO 850, UMF+20) loaded nano-formulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: QA108 Phase II Study in Subjects With Intermediate Age-Related Macular Degeneration
Status: COMPLETED
Conditions: Intermediate Age-Related Macular Degeneration
Interventions: DRUG: QA108 granules|DRUG: QA108 granules placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Motor-Point Stimulation for Conditioning the Diaphragm of Patients With Amyotrophic Lateral Sclerosis (ALS)
Status: UNKNOWN
Conditions: Amyotrophic Lateral Sclerosis (ALS)
Interventions: DEVICE: Intramuscular diaphragm electrodes
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase IIa Clinical Study of Puesta Mesylate for Injection in Patients With T-Cell Lymphoma and Cutaneous T-Cell Lymphoma
Status: RECRUITING
Conditions: Relapsed or Refractory Peripheral T-cell Lymphoma (PTCL)|Cutaneous T-cell Lymphoma (CTCL)
Interventions: DRUG: 11.2 mg/m2 Purinostat Mesylate|DRUG: 15 mg/m2 Purinostat Mesylate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Non-interventional Study Evaluating Clinical Utility and Implications on Improved Patient Management of Serum Neurofilament as a Prognostic Marker for Disease Activity in Patients With Relapsing Multiple Sclerosis
Status: NOT_YET_RECRUITING
Conditions: Multiple Sclerosis
Interventions: OTHER: ofatumumab|OTHER: DMT category 1
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Performance and Safety of I-020805 in Prevention of Cerebrospinal Fluid (CSF) Leakage Following Elective Craniotomy
Status: COMPLETED
Conditions: Cerebrospinal Fluid Leakage
Interventions: DEVICE: I-020805
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Clinical Trial to Evaluate the Use of an Adsorption Membrane (oXiris®) During Cardiopulmonary Bypass Surgery
Status: COMPLETED
Conditions: Cardiac Surgical Procedures|Cardiopulmonary Bypass
Interventions: DEVICE: OXIRIS®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Preoperative Muscle Training on Postoperative Orthopaedic Surgery Recovery
Status: COMPLETED
Conditions: Arthroplasty|Osteoarthritis
Interventions: OTHER: Rehabilitation|OTHER: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Laparoscopic Versus Open Devascularization for Portal Hypertension, a Randomized Controlled Trial
Status: UNKNOWN
Conditions: Portal Hypertension|Liver Cirrhosis
Interventions: PROCEDURE: open surgical procedure|PROCEDURE: laparoscopic surgical procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Schedules of Dexamethasone in Patients Incorrectly Taking Dexamethasone Premedication (REaCT-dexamethasone)
Status: COMPLETED
Conditions: Cancer
Interventions: DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Repurposing Probenecid as a Positive Inotrope for the Treatment of Heart Failure
Status: COMPLETED
Conditions: Systolic Heart Failure
Interventions: DRUG: Probenecid 1 gr oral twice daily|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study for Patients That Have Been Previously Been Treated in Waldenstrom's Macroglobulinemia or Multiple Myeloma
Status: COMPLETED
Conditions: Waldenstrom's Macroglobulinemia|Multiple Myeloma
Interventions: DRUG: Enzastaurin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ex-Plissit Model Based Counseling on Sexual Function and Sexual Satisfaction
Status: COMPLETED
Conditions: MS (Multiple Sclerosis)|Sexual Dysfunctions|Counseling
Interventions: OTHER: Sexual counseling, based on the extended (EX-PLISSIT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Serological Evaluation of Varicella and Hepatitis A Vaccines Using Injector Delivery
Status: UNKNOWN
Conditions: Varicella|Hepatitis A
Interventions: BIOLOGICAL: Varicella Vaccine|BIOLOGICAL: Hepatitis A Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: An Open-label, Single-dose, Two-treatment, Randomized, Cross-over Study to Investigate the Effects of the SLCO2B1 c.1457C>T Polymorphism and Apple Juice on the Pharmacokinetics and Pharmacodynamics of Acebutolol in Healthy Korean and Japanese Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Acebutolol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Aminolevulinic Acid Used to Enhance Visualization and Surgical Removal of Brain Tumors
Status: TERMINATED
Conditions: Malignant Glioma|Glioma|Glioblastoma|Glioblastoma Multiforme|Astrocytoma
Interventions: DRUG: Aminolevulinic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Passive Heat Therapy in Patients With Chronic Kidney Disease
Status: RECRUITING
Conditions: Renal Insufficiency, Chronic
Interventions: PROCEDURE: Whole-body Passive Heat Therapy (HT)|PROCEDURE: Thermoneutral Control (CON)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: 68Ga-PMD22 PET/CT Examination Targeting CLDN18.2
Status: RECRUITING
Conditions: Gastrointestinal Cancer
Interventions: DRUG: Intravenous injection of 68Ga-PMD22
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety and Tolerability Study of K0706 in Subjects With Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: DRUG: K0706|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Freedom® Cervical Disc Use In The Treatment of Cervical Degenerative Disc Disease
Status: UNKNOWN
Conditions: Symptomatic Cervical Degenerative Disc Disease (DDD) From C3-C7
Interventions: DEVICE: Freedom Cervical Disc
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Erythropoietin in Radiocontrast Induced Nephropathy (ERIN) Trial
Status: TERMINATED
Conditions: Contrast Induced Nephropathy
Interventions: DRUG: erythropoeitin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Integrated Moral Reasoning Development Intervention for Management of Violence in Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia|Moral Status|Violence
Interventions: OTHER: integrated Moral Reasoning Development Intervention (MRDI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of Phrenic Nerve Block on Postoperative Shoulder Pain in Patients for Liver Resection.
Status: UNKNOWN
Conditions: Shoulder Pain|Surgery|Nerve Block
Interventions: DRUG: Ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Memantine Treatment for Obsessive-compulsive Disorder and Generalized Anxiety Disorder
Status: COMPLETED
Conditions: Obsessive-Compulsive Disorder|Generalized Anxiety Disorder
Interventions: DRUG: Memantine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Influence of Nevirapine to Atazanavir in Steady State Equilibrium in HIV Patients
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Atazanavir (Reyataz)|DRUG: Ritonavir (Norvir)|DRUG: Nevirapine (Viramune)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Text Messaging for Human Immunodeficiency Virus (HIV) Testing in Sexual and Gender Minority (SGM) Teens
Status: RECRUITING
Conditions: HIV
Interventions: BEHAVIORAL: Information, motivation, behavioral skills treatment arm|BEHAVIORAL: Information only control arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: the Effect of Exercise and Oral Supplement Intervention in Sarcopenia Markers in Hemodialysis Patients
Status: ENROLLING_BY_INVITATION
Conditions: Sarcopenia
Interventions: OTHER: 1 hour combined intervention ( Exercise and nutrition)|OTHER: 3 hours combined intervention ( Exercise and nutrition)|DIETARY_SUPPLEMENT: Nutrition intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevention of Postoperative Hypocalcemia of Oral Vitamin D Supplementation Before Total Thyroidectomy
Status: RECRUITING
Conditions: Total Thyroidectomy|Hypocalcemia|Vitamin D Deficiency
Interventions: DRUG: Cholecalciferol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparison Between Lactulose and Lactulose-Paraffin in Cirrhotic Patients
Status: COMPLETED
Conditions: Cirrhosis|Hepatic Encephalopathy
Interventions: DRUG: Comparison between Lactulose and Lactulose-Paraffin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Azithromycin in Bronchiolitis Obliterans Syndrome
Status: COMPLETED
Conditions: Bronchiolitis Obliterans Syndrome|Graft Rejection|Lymphocytic Bronchiolitis|Respiratory Infection
Interventions: DRUG: Azithromycin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Calcium Channel Blockade in Primary Aldosteronism
Status: COMPLETED
Conditions: Primary Aldosteronism|Primary Aldosteronism Due to Adrenal Hyperplasia (Bilateral)
Interventions: DRUG: Amlodipine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sintilimab in Combination With Chemoradiotherapy in High-risk Locoregionally-advanced Nasopharyngeal Carcinoma
Status: RECRUITING
Conditions: Nasopharyngeal Carcinoma|Sintilimab
Interventions: DRUG: Sintilimab (PD-1 Antibody)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Oral Administration of Anti-CD3 Monoclonal Antibody in Non-responder Genotype-I Chronic Hepatitis C Subjects
Status: UNKNOWN
Conditions: Chronic Hepatitis C
Interventions: DRUG: anti-CD3 monoclonal antibody|DRUG: Sodium Chloride placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Probiotic Supplementation With Weight Reducing Plan in Patients With Food Addiction and Weight Regain After Bariatric Surgery
Status: COMPLETED
Conditions: Weight Regain After Bariatric Surgery and Food Addiction
Interventions: DIETARY_SUPPLEMENT: Probiotic supplement|OTHER: Placebo supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hepatic Histopathology in Urea Cycle Disorders
Status: RECRUITING
Conditions: Urea Cycle Disorder|Ornithine Transcarbamylase Deficiency|Citrullinemia 1|ARGI Deficiency|ASL Deficiency|Argininosuccinic Aciduria|ASS Deficiency|Hyperargininemia|Carbamyl Phosphate Synthetase Deficiency|NAGS Deficiency
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phase II Study of Ultra-high-dose Hypofractionated vs. Single-dose Image-Guided Radiotherapy for Prostate Cancer
Status: COMPLETED
Conditions: PROSTATE CANCER
Interventions: RADIATION: IGRT 45 Gy in 5 fractions of 9 Gy|RADIATION: IGRT 24 Gy single dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Proof of Mechanism of a New Ketogenic Supplement Using Dual Tracer PET (Positron Emission Tomography)
Status: COMPLETED
Conditions: Mild Cognitive Impairment
Interventions: DIETARY_SUPPLEMENT: ketogenic drink|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Renalof in the Treatment of Elderly Patients With Gallstones
Status: COMPLETED
Conditions: Cholelithiasis
Interventions: DIETARY_SUPPLEMENT: Renalof|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nalbuphine Versus Ketamine for Prevention of Emergence Agitation After Sevoflurane in Children Undergoing Tonsillectomy
Status: COMPLETED
Conditions: Pediatric ALL|Pediatric Anesthesia
Interventions: DRUG: Nalbuphine Injection|DRUG: Ketamine|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Predicting 28-Day Mortality in Subarachnoid Hemorrhage
Status: COMPLETED
Conditions: Subarachnoid Hemorrhage, Aneurysmal
Interventions: OTHER: Glasgow coma scale|OTHER: Hunt-Hess scale|OTHER: World Federation of Neurological Surgeons (WFNS) scale|OTHER: modified Fisher scale|OTHER: VASOGRADE scale|OTHER: Ogilvy and Carter scale
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Carboxyamidotriazole and Paclitaxel in Treating Patients With Advanced Solid Tumors or Refractory Lymphomas
Status: COMPLETED
Conditions: Brain and Central Nervous System Tumors|Breast Cancer|Kidney Cancer|Lung Cancer|Lymphoma|Melanoma (Skin)|Ovarian Cancer|Small Intestine Cancer|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: carboxyamidotriazole|DRUG: paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Assessment of the Emfit Mattress Sensor for Detection and Alarm of Night-time Generalized Tonic-clonic Seizures.
Status: UNKNOWN
Conditions: Epilepsy|Seizures
Interventions: DEVICE: Emfit mattress sensor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effect of Micro Fragmented Adipose Tissue (MFAT) on Knee Osteoarthritis
Status: ACTIVE_NOT_RECRUITING
Conditions: Osteoarthritis, Knee|Knee Pain
Interventions: BIOLOGICAL: Micro Fragmented Adipose Tissue|BIOLOGICAL: Corticosteroid injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of Tdap Vaccine Compared to DTaP Vaccine in Children 4 to 6 Years of Age
Status: COMPLETED
Conditions: Tetanus|Diphtheria|Pertussis
Interventions: BIOLOGICAL: Tdap (Tetanus Toxoid Reduced Diphtheria Toxoid/Acellular Pertussis)|BIOLOGICAL: DTaP (Diphtheria & Tetanus Toxoids & Acellular Pertussis Adsorbed)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The 90% Effective Flow of High Flow Nasal Oxygenation (HFNO) During Sedated Bronchoscopy
Status: COMPLETED
Conditions: Hypoxia
Interventions: DEVICE: high flow nasal cannula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of BIA 5-1058 400 mg on Warfarin Pharmacokinetics
Status: COMPLETED
Conditions: Pulmonary Arterial Hypertension
Interventions: DRUG: BIA 5-1058|DRUG: Warfarin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endotracheal Tube Cuff Pressures in Ventilated Patients
Status: COMPLETED
Conditions: Pneumonia, Ventilator-Associated
Interventions: OTHER: monitoring of cuff pressures
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Glutamine to Treat Intestinal Permeability in Functional Dyspepsia
Status: RECRUITING
Conditions: Functional Dyspepsia
Interventions: DRUG: Glutamine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bosutinib in Combination With Pemetrexed in Patients With Selected Metastatic Solid Tumors
Status: COMPLETED
Conditions: Carcinoma, Non-Small-Cell Lung|Mesothelioma|Bladder Cancer|Ovarian Cancer|Peritoneal Cancer|Thymoma|Thymus Cancer|Uterine Cervical Cancer
Interventions: DRUG: Bosutinib|DRUG: Pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sub-Hertz Analysis of Viscoelasticity of Limbs in Patients With Lymphedema
Status: ENROLLING_BY_INVITATION
Conditions: Lymphedema
Interventions: DIAGNOSTIC_TEST: Ultrasound Procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: FCR and Bevacizumab in the Treatment of Relapsed Chronic Lymphocytic Leukemia (CLL)
Status: COMPLETED
Conditions: Chronic Lymphocytic Leukemia
Interventions: DRUG: Fludarabine|DRUG: Cyclophosphamide|DRUG: Rituximab|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT