pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Optical Coherence Tomography Guided C&D
Status: WITHDRAWN
Conditions: Basal Cell Carcinoma
Interventions: DEVICE: Optical Coherence Tomography (OCT)|PROCEDURE: Curettage & Desiccation (C&D) Procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: PET/MRI in Patients With Suspected Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: 68Ga- PSMA-HBED-CC|DEVICE: Biograph mMR, Siemens
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Omega-6/Omega-3 Ratio and Neural Development in Preterm Infants.
Status: COMPLETED
Conditions: Impaired Psychomotor Development
Interventions: DIETARY_SUPPLEMENT: Preterm infants formula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SCREENING
Clinical trial: Effectiveness of Board Game on Improving Elementary School Students' Infection Control
Status: COMPLETED
Conditions: Knowledge of Infection Control|Attitude of Infection Control|Behavioral Intentions of Infection Control
Interventions: OTHER: gamified instruction|OTHER: conventional lesson lecture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Mismatch vs. Standard Intervention During Memory Reconsolidation Blockade With Propranolol: Effect on Psychophysiological Reactivity During Traumatic Imagery
Status: RECRUITING
Conditions: Stress Disorders, Post-Traumatic
Interventions: BEHAVIORAL: Memory reactivation procedures|DRUG: Propranolol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Endoscopic Biliary Drainage in Malignant High Grade Biliary Stricture
Status: TERMINATED
Conditions: Malignant Biliary Stricture
Interventions: PROCEDURE: ERCP with biliary stenting|PROCEDURE: EUS guided biliary drainage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of OC000459 Dosed Twice Daily for 28 Days in Asthmatic Subjects
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: OC000459|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Smoking Cessation in Menthol Flavored Cigarette Smokers
Status: COMPLETED
Conditions: Tobacco Use Disorder
Interventions: OTHER: switch to non-menthol cigarettes prior to cessation attempt|OTHER: continue smoking menthol cigarettes prior to cessation attempt
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Feasibility of PCI Using a 7-Fr Thin-Walled Sheath Via the DRA
Status: ACTIVE_NOT_RECRUITING
Conditions: Coronary Artery Disease|Distal Radial Artery|Complex Intervention
Interventions: PROCEDURE: Percutaneous coronary intervention via the distal radial approach
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Annular Reshaping of the Mitral Valve for Patients With Mitral Regurgitation Using the Millipede IRIS System
Status: COMPLETED
Conditions: Mitral Valve Insufficiency
Interventions: DEVICE: Mitral Valve IRIS Ring
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Risk Factors for Development of Incisional Hernia in Transverse Incisions
Status: UNKNOWN
Conditions: Incisional Hernia|Malignancy
Interventions: PROCEDURE: Mass closure technique|PROCEDURE: Layered closure technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Cx611-0204 SEPCELL Study
Status: COMPLETED
Conditions: Bacterial Pneumonia
Interventions: BIOLOGICAL: Cx611|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: TPO-Mimetic Use in Children for Hematopoietic Failure
Status: COMPLETED
Conditions: Bone Marrow Failure Disorders|Aplastic Anemia|Thrombocytopenia|Refractory Cytopenia of Childhood|Myelodysplastic Syndrome(MDS)
Interventions: DRUG: Romiplostim
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study in Participants With Acute Major Bleeding to Evaluate the Ability of Andexanet Alfa to Reverse the Anticoagulation Effect of Direct and Indirect Oral Anticoagulants (Extension Study)
Status: COMPLETED
Conditions: Bleeding
Interventions: BIOLOGICAL: Andexanet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Usefulness of Supportive SMS in Addition to an Internet Based Quit Smoking Program (Www.Slutta.no)
Status: COMPLETED
Conditions: Smoking Cessation|Smoking
Interventions: DEVICE: Internet-based behavioral coaching|DEVICE: SMS based coaching|DEVICE: SMS coaching - UNN recruited|DEVICE: SMS craving function - UNN recruited
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Ultra Low Dose CT and Use of Iomeron 400 in PCD-CT
Status: RECRUITING
Conditions: Radiation Exposure|Lung Embolism|Lung Cancer|Pneumonia
Interventions: RADIATION: Computed Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effects of Breezy Candy on Halitosis
Status: UNKNOWN
Conditions: Halitosis
Interventions: OTHER: no scraping microcapsules|OTHER: scraping microcapsules containing inert TCP microcapsules|OTHER: scraping microcapsules containing Propolis|OTHER: scraping microcapsules containing and Zinc|OTHER: scraping microcapsules containing Propolis and Zinc
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase IIa Trial to Determine the Effects of Bardoxolone Methyl on Renal Function in Patients With Diabetic Nephropathy
Status: COMPLETED
Conditions: Diabetic Nephropathy
Interventions: DRUG: RTA 402 (Bardoxolone Methyl)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rehabilitation Exercise Using Digital Healthcare System in Patients With Anterior Cruciate Ligament Reconstruction
Status: UNKNOWN
Conditions: Anterior Cruciate Ligament Injuries
Interventions: DEVICE: Rehabilitation using Digital Healthcare System (Uincare Homeplus)|OTHER: Conventional Rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Improving Health Equity for COVID-19 Vaccination for At-risk Populations Using Online Social Networks
Status: ACTIVE_NOT_RECRUITING
Conditions: Vaccination Refusal|Covid19|Heart Diseases
Interventions: BEHAVIORAL: Online Social Network and Collective Intelligence Intervention|BEHAVIORAL: Independent Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Local Therapy for Oligorecurrent and Oligometastatic Esophageal Squamous Cell Carcinoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Oligorecurrent and Oligometastatic Esophageal Squamous Cell Carcinoma
Interventions: OTHER: Radiation, Surgery or Radiofrequency ablation|DRUG: Systemic therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Renoprotective Effects of Fluid Prophylaxis Strategies for Contrast Induced Nephropathy (CIN)
Status: WITHDRAWN
Conditions: Contrast Induced Nephropathy
Interventions: DRUG: Bicarbonate Hydration|DRUG: Hypotonic hydration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: SM-1 vs. an Active Comparator in A Model of Transient Insomnia
Status: NOT_YET_RECRUITING
Conditions: Transient Insomnia
Interventions: DRUG: SM-1|DRUG: Active Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: ALL Reconstruction Versus Modified Lemaire's LET in Combination With ACL Reconstruction With a Minimum Follow up of 2 Years
Status: RECRUITING
Conditions: Anterior Cruciate Ligament Injuries
Interventions: PROCEDURE: ACL reconstruction with hamstrings combined with ALL plasty|PROCEDURE: ACL reconstruction with hamstrings combined with modified Lemaire's LET
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Study to Evaluate the Safety, Feasibility and Immunogenicity of an Allogeneic, Cell-based Vaccine (DCP-001) in High Grade Serous Ovarian Cancer Patients After Primary Treatment
Status: ACTIVE_NOT_RECRUITING
Conditions: Ovarian Cancer
Interventions: BIOLOGICAL: DCP-001
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chiropractic Dosage for Lumbar Stenosis
Status: COMPLETED
Conditions: Lumbar Spinal Stenosis
Interventions: PROCEDURE: flexion distraction|OTHER: placebo control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Physical Rehabilitation Program for Cardiorespiratory Health and Quality of Life Among Breast Cancer Survivors in UAE.
Status: RECRUITING
Conditions: Breast Cancer
Interventions: OTHER: Supervised Training|OTHER: Individually tailored home program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Paraorbital-Occipital Electric Stimulation in Patients With Optic Neuropathy (BCT_optnerve)
Status: COMPLETED
Conditions: Visual Impairment
Interventions: DEVICE: rtACS (verum condition)|DEVICE: placebo stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Programmed Intermittent Epidural Bolus Time Interval and Injection Volume
Status: COMPLETED
Conditions: Labor Pain
Interventions: PROCEDURE: Programmed Intermittent Epidural Bolus (PIEB)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Biodegradable Synthetic Scaffold as a Substitute for hAM in Limbal Epithelial Cells Transplant in LSCD Patients
Status: COMPLETED
Conditions: Limbal Stem Cell Deficiency
Interventions: DEVICE: PLGA scaffold
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Volumetric Analysis of Alveolar Ridge Contour Using Sub-epithelial Connective Tissue Graft
Status: COMPLETED
Conditions: Alveolar Ridge Collapse
Interventions: OTHER: SubEpithelial connective graft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Carboplatin With or Without Decitabine in Treating Patients With Progressive, Advanced Ovarian Epithelial Cancer, Fallopian Tube Cancer, or Primary Peritoneal Cancer
Status: TERMINATED
Conditions: Fallopian Tube Cancer|Ovarian Cancer|Peritoneal Cavity Cancer
Interventions: DRUG: carboplatin|DRUG: decitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combined Intensive and Conventional Exercise on Nonalcoholic Fatty Liver Disease (NAFLD)
Status: COMPLETED
Conditions: Non-alcoholic Fatty Liver Disease (NAFLD)
Interventions: OTHER: Intensive exercise|OTHER: Conventional exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Determine the Safety and Efficacy of Albiglutide in Subjects With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: placebo to match albiglutide|BIOLOGICAL: albiglutide|DRUG: metformin|DRUG: glimepiride|DRUG: pioglitazone|DRUG: placebo to match pioglitazone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Moderately Preterm Infants With Caffeine at Home for Apnea (MoCHA) Trial
Status: TERMINATED
Conditions: Apnea of Prematurity
Interventions: DRUG: Caffeine Citrate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effectiveness, Safety, and Tolerability of Canagliflozin in Combination With Metformin in the Treatment of Patients With Type 2 Diabetes Mellitus With Inadequate Glycemic Control With Diet and Exercise
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Canagliflozin 100 mg|DRUG: Canagliflozin 300 mg|DRUG: Metformin XR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Nutrition and Swallowing Function of Head and Neck Cancer Patients During the Course of Treatment
Status: WITHDRAWN
Conditions: Head and Neck Cancer|Surgery|Nutrition|Swallowing
Interventions: BEHAVIORAL: nutrition /swallowing counseling|BEHAVIORAL: G-tube/swallowing intervention|BEHAVIORAL: nutrition /swallowing intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Investigation of the Acute Effect of Myofascial Release Techniques and Dynamic Stretch on Vertical Jump Performance in Recreationally Active Individuals
Status: COMPLETED
Conditions: Healthy
Interventions: DEVICE: Graston Technique|OTHER: Dynamic stretch exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Interaction Study of Clopidogrel 300/75 mg Given Alone or Concomitantly With Pantoprazole 80 mg in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Clopidogrel|DRUG: Placebo|DRUG: Pantoprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: GKT137831 in IPF Patients With Idiopathic Pulmonary Fibrosis
Status: RECRUITING
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: OTHER: Placebo Oral Tablet|DRUG: GKT137831
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dosing Regimen of Eculizumab Added to Conventional Treatment in Positive Crossmatch Deceased Donor Kidney Transplant
Status: TERMINATED
Conditions: Kidney Transplant
Interventions: DRUG: Eculizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Etiology of Sleep Apnea-related Hyperaldosteronism - BP Treatment
Status: COMPLETED
Conditions: Obstructive Sleep Apnea|Resistant Hypertension|Hyperaldosteronism
Interventions: DRUG: Spironolactone|DRUG: BP medication uptitration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: VELCADE in MALT Lymphoma Pretreated With Prior Systemic Therapy
Status: COMPLETED
Conditions: Lymphoma, Mucosa-Associated Lymphoid Tissue
Interventions: DRUG: Bortezomib (drug)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Changing to TRAVATAN® From Prior Therapy
Status: COMPLETED
Conditions: Open-Angle Glaucoma|Ocular Hypertension
Interventions: DRUG: Travoprost 0.004%
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Outcomes of Patients Not Responding to Antibiotics in the Community
Status: COMPLETED
Conditions: Sinusitis|Bronchitis, Chronic|Pneumonia, Bacterial
Interventions: DRUG: all macrolide antibiotics|DRUG: all beta-lactam antibiotics
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: HEP-FYN 12-Years Follow-up
Status: UNKNOWN
Conditions: Peptic Ulcer|Dyspepsia|Reflux
Interventions: OTHER: 13C-Urea breath test for Helicobacter Pylori|OTHER: Questionaire
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Prospective and Non-randomized Registry of CardioCel 3D
Status: RECRUITING
Conditions: Intracardiac and Septal Defects|Valve and Anulus Repair|Great Vessel Reconstruction|Peripheral Vessel Reconstruction|Suture Line Buttressing
Interventions: DEVICE: CardioCel implantation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Directional Subthalamic Deep Brain Stimulation on Gait and Balance in Parkinson's Disease Patients
Status: UNKNOWN
Conditions: Parkinson Disease
Interventions: PROCEDURE: Directional and single ring STN-DBS on gait
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of I COUGH Program to Dyspnea, Respiratory Parameters, Mobility and Pain After Major Abdominal Surgery
Status: COMPLETED
Conditions: Dyspnea|Pain|Respiratory Insufficiency|Mobility Limitation
Interventions: OTHER: I COUGH care program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Target Engagement of Centella Asiatica in Cognitive Impairment
Status: RECRUITING
Conditions: Mild Cognitive Impairment|Alzheimer's Disease
Interventions: DRUG: Centella asiatica product|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Trauma-Focused Cognitive-Behavioral Therapy (TF-CBT) for Children With Post-traumatic Stress Disorder (TreatChildTrauma)
Status: COMPLETED
Conditions: Post-Traumatic Stress Disorder
Interventions: BEHAVIORAL: Trauma-Focused Cognitive Behavioral Therapy (TF-CBT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of TQB2450 Combined With Anlotinib in Patients With Advanced Non-small Cell Lung Cancer（NSCLC）
Status: UNKNOWN
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: TQB2450|DRUG: Anlotinib|DRUG: Anlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SPA Therapy in the Treatment of Sleep Apnea Syndrome
Status: WITHDRAWN
Conditions: Obstructive Sleep Apnea Syndrome|Chronic Venous Insufficiency
Interventions: OTHER: 3-week immediate SPA treatment|OTHER: 3-week late SPA treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: REnin-guided TherApy With MinEralocorticoid Receptor Antagonists in Primary Aldosteronism - Feasibility Study
Status: RECRUITING
Conditions: Primary Aldosteronism
Interventions: OTHER: Renin measurements
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Osteoporosis, Trabecular Bone Score and Fracture Risk Assessment in Male Patients After Radical Cystectomy
Status: COMPLETED
Conditions: Osteoporosis|Bladder Disease
Interventions: DIAGNOSTIC_TEST: Bone mineral density (BMD)|DIAGNOSTIC_TEST: Trabecular bone score (TBS)|DIAGNOSTIC_TEST: Fracture risk Assessment Tool (FRAX)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Zip-Stitch™ for Vaginal Cuff Closure in Laparoscopic Hysterectomy - Safety & Efficacy Study
Status: TERMINATED
Conditions: Laparoscopic Hysterectomy
Interventions: DEVICE: Zip-stitch(TM)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The WavelinQ™ Arterio-Venous Endovascular Fistula: A Global, Post-Market Investigation
Status: TERMINATED
Conditions: End Stage Kidney Disease|Chronic Kidney Diseases|Kidney Failure|Kidney Insufficiency|Kidney Disease, Chronic|AV Fistula|Fistulas Arteriovenous
Interventions: DEVICE: WavelinQ™ EndoAVF System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improving Care Pathway Using Simplified Digital Tools for Oncology Patients: a Multicenter "Before-and-after" Study
Status: NOT_YET_RECRUITING
Conditions: Oncology|Adverse Event|Numeric Application|Care Telemonitoring|Compliance, Treatment|Patient Reported Outcome (PRO)
Interventions: OTHER: Nouveal numeric application "Onco'nect"
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Statins on Asthma Control in Smokers With Asthma
Status: COMPLETED
Conditions: Asthma|COPD|Smoking
Interventions: DRUG: Atorvastatin|DRUG: atorvastatin|DRUG: matched placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Reducing Hypotensive Anesthesia Use With TXA During Orthognathic Surgery
Status: ENROLLING_BY_INVITATION
Conditions: Hypotension During Surgery|Blood Loss, Surgical
Interventions: OTHER: Avoidance of Deliberate Hypotensive Anesthesia|DRUG: TRANEXAMIC ACID 1 G in 10 mL INTRAVENOUS INJECTION, SOLUTION
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Safety of Transcranial Direct Current Stimulation in the Subacute Phase After Stroke
Status: COMPLETED
Conditions: Stroke
Interventions: DEVICE: Active tDCS|OTHER: Physical Therapy|DEVICE: Sham tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Frail Status of Elderly Patients After Repair and Anesthesia Guided by the bispectraL Index
Status: TERMINATED
Conditions: Anesthesia, General|Aged, 70 and Over
Interventions: OTHER: Toolbox: Automated group|OTHER: Manual group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Efficacy of Venavine Intensive® on the Quality of Life in Females With Chronic Venous Insufficiency
Status: COMPLETED
Conditions: Venous Insufficiency
Interventions: OTHER: Gelatine Capsule|OTHER: Venavine Intensive®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: The Effect of SHR20004（Noiiglutide ） on Body Weight in Obese Subjects Without Diabetes
Status: UNKNOWN
Conditions: Obesity
Interventions: DRUG: SHR20004|DRUG: SHR20004|DRUG: SHR20004|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Adenoviral Endostatin in the Treatment of Advanced Solid Tumor
Status: UNKNOWN
Conditions: Advanced Solid Tumor
Interventions: DRUG: Antangiogenesis|GENETIC: endostatin gene
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Statins for Venous Event Reduction in Patients With Venous Thromboembolism
Status: RECRUITING
Conditions: Venous Thromboembolism|Blood Clot|Post Thrombotic Syndrome
Interventions: DRUG: Rosuvastatin Calcium|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase III Study Assessing the Efficacy and Safety of Pegcetacoplan in Patients With C3 Glomerulopathy or Immune-Complex Membranoproliferative Glomerulonephritis
Status: ACTIVE_NOT_RECRUITING
Conditions: C3G|IC-MPGN|C3 Glomerulopathy|C3 Glomerulonephritis|Complement 3 Glomerulopathy|Complement 3 Glomerulopathy (C3G)|Complement 3 Glomerulonephritis|Dense Deposit Disease|DDD|Membranoproliferative Glomerulonephritis|Membranoproliferative Glomerulonephritis (MPGN)|Immune Complex Membranoproliferative Glomerulonephritis (IC-MPGN)
Interventions: DRUG: Pegcetacoplan|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Studying DNA in Blood and Bone Marrow Samples From Younger Patients With Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Adult Acute Myeloid Leukemia in Remission|Childhood Acute Myeloid Leukemia in Remission
Interventions: OTHER: Laboratory Biomarker Analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Deep Neuromuscular Blockade on Postoperative Shoulder Tip Pain After Laparoscopic Cholecystectomy
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: DRUG: Rocuronium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Hypofractionated Radiation Therapy for Treating Prostate Cancer High-Risk Features Following Radical Prostatectomy
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Adenocarcinoma|Stage IIB Prostate Cancer AJCC v8|Stage III Prostate Cancer AJCC v8|Stage IIIA Prostate Cancer AJCC v8|Stage IIIB Prostate Cancer AJCC v8|Stage IIIC Prostate Cancer AJCC v8
Interventions: DRUG: Androgen Suppression|RADIATION: Hypofractionated Radiation Therapy|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Taper Or Abrupt Steroid Stop: TOASSTtrial
Status: RECRUITING
Conditions: Inflammatory Disorder|Autoimmune
Interventions: DRUG: Prednisone|OTHER: Placebo Arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sensory Motor Interventions on Preterm Infants
Status: NOT_YET_RECRUITING
Conditions: Preterm Infants
Interventions: BEHAVIORAL: oral stimulation|BEHAVIORAL: infants massage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Value of Measuring Cervical Angle and Length by Ultrasound in Prediction of Successful Induction of Delivery
Status: COMPLETED
Conditions: Induced; Birth
Interventions: DIAGNOSTIC_TEST: Transvaginal ultrasound|DIAGNOSTIC_TEST: Vaginal examination
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Effectiveness and Safety of BMS-986165 Compared to Placebo and Active Comparator in Participants With Psoriasis
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: BMS-986165|OTHER: Placebo|DRUG: Apremilast
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comapre Effects Of Proprioceptive Training And Core Instability Strength Training In Knee Osteoarthritis Patients
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: OTHER: Conservational Physical Therapy and Proprioceptive Strength Training|OTHER: Conservational Physical Therapy and Core Instability Strength Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Questionnaire and Tissue Banking For Multiple Myeloma, Waldenstrom Macroglobulinemia and Related Disorders
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Myeloma|Waldenstrom's Macroglobulinemia|Smoldering Multiple Myeloma|Lymphoblastic Lymphoma
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: 3D HD Versus 2D HD in Cholecystectomy
Status: UNKNOWN
Conditions: Cholelithiasis|Gall Bladder Disease
Interventions: DEVICE: 3D HD laparoscopy|DEVICE: 2D HD laparoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Levalbuterol, Racemic Albuterol and Placebo in Subjects Twelve Years of Age and Older With Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: levalbuterol tartrate MDI|DRUG: racemic albuterol MDI|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sympathetic Regulation of Large Artery Stiffness in Humans With ISH
Status: RECRUITING
Conditions: Hypertension, Systolic|Stiffness, Aortic
Interventions: DRUG: Clonidine|DRUG: Hydrochlorothiazide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility, Acceptability and the Effects of Two Publicly Available Physical Activity Mobile Apps
Status: COMPLETED
Conditions: PHYSICAL FITNESS
Interventions: DEVICE: Exercise app: 7 Minute Workout Challenge|DEVICE: Running app: One You Couch to 5K
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Myofascial Release in Addition to Foot Core Exercises in Young Adults With Asymptomatic Flexible Pes Planus
Status: COMPLETED
Conditions: Pes Planus
Interventions: OTHER: Foam Roller|OTHER: Foot Core Exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ZENFlex-Registry to Evaluate the Outcome of Bare Metal Stent-assisted Angioplasty
Status: UNKNOWN
Conditions: Atherosclerosis of Femoral Artery
Interventions: DEVICE: ZENFLEX peripheral stent system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exosome-miRNA and Transcriptome Profiling of Dry Eye Syndrome and Sjogren's Syndrome
Status: NOT_YET_RECRUITING
Conditions: Dry Eye Syndrome|Sjogren's Syndrome|Xerophthalmia
Interventions: OTHER: TBDESJS|OTHER: Acupuncture
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Cognitive Training Video Game to Target Subclinical Depressive Symptoms in Youth
Status: ACTIVE_NOT_RECRUITING
Conditions: Depression|Subclinical Depressive Symptoms
Interventions: DEVICE: Computerized cognitive training (CCT) using EndeavorRx
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Hartmann vs R/A in Peritonitis by Perforated Diverticulitis
Status: COMPLETED
Conditions: Peritonitis Caused by Perforated Left-sided Colon Diverticulitis
Interventions: PROCEDURE: Primary sigmoid resection with end colostomy (Hartmann)|PROCEDURE: Primary sigmoid resection and immediate anastomosis with diverting stoma (PRA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: Validation of the RADIAL Algorithm for Diagnosis of Autosomal Recessive Cerebellar Ataxia
Status: RECRUITING
Conditions: Autosomal Recessive Cerebellar Ataxia
Interventions: GENETIC: Genetic diagnosis (PMDA panel)|DIAGNOSTIC_TEST: Use of RADIAL algorithm
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study to Determine the Effectiveness of GSK1120212 in BRAF Mutation-positive Melanoma Previously Treated With or Without a BRAF Inhibitor
Status: COMPLETED
Conditions: Cancer
Interventions: DRUG: GSK1120212
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Photobiomodulation to Demonstrate Safety and Reduce the Incidence of Oral Mucositis in Adult Head & Neck Cancer Patients
Status: COMPLETED
Conditions: Oral Mucositis (Ulcerative)|Oral Mucositis (Ulcerative) Due to Radiation|Oral Mucositis (Ulcerative) Due to Antineoplastic Therapy|Head and Neck Cancer
Interventions: DEVICE: Photobiomodulation|OTHER: Routine Oral Care and Analgesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Feasibility & Effect of a Tele-rehabilitation Program in Pulmonary Sarcoidosis Pulmonary Sarcoidosis
Status: RECRUITING
Conditions: Sarcoidosis, Pulmonary|Telerehabilitation
Interventions: BEHAVIORAL: Telerehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Different Doses of Indacaterol in Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Indacaterol|DRUG: Salmeterol 50 μg|DRUG: Placebo to indacaterol|DRUG: Placebo to salmeterol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Therapy Using Cellcept and Rebif in RRMS
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DRUG: mycophenolate mofetil (Cellcept)|DRUG: human interferon beta 1a (Rebif)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Efficacy and Safety of Treatments for Patients Hospitalized for COVID-19 Infection Without Signs of Acute Respiratory Failure, in Tunisia
Status: WITHDRAWN
Conditions: COVID 19|Patients Hospitalized
Interventions: DRUG: HCQ|DRUG: Azithromycin|DRUG: Doxycycline|DIETARY_SUPPLEMENT: Zinc
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Antiretroviral Therapy and Pre-exposure Prophylaxis for HIV Prevention Among Female Sex Workers in Cotonou, Benin
Status: COMPLETED
Conditions: Adherence to Medication Regime
Interventions: BIOLOGICAL: TasP using ART regimen as per Benin guidelines|BIOLOGICAL: PrEP using Truvada
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Cognitive Stimulation Therapy for Dementia: A Two-Armed Pragmatic Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Dementia|Cognitive Impairment, Mild|Dementia, Vascular|Dementia, Mixed|Dementia With Lewy Bodies|Dementia Frontal|Dementia Moderate|Dementia of Alzheimer Type|Dementia, Mild
Interventions: BEHAVIORAL: Referral for Cognitive Stimulation Therapy|OTHER: No change to Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Multi-Indication, Retrospective Oncological Study to Validate the Accuracy in Predicting TTP by PrediCare in Patients Under SOC
Status: UNKNOWN
Conditions: Non-Small Cell Lung Cancer|Small Cell Lung Cancer|Prostate Cancer|Breast Cancer|Colon Cancer
Interventions: DEVICE: PrediCare
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Oat and Cholesterol
Status: COMPLETED
Conditions: Elevated LDL Cholesterol
Interventions: OTHER: Active oat beverage|OTHER: Control rice beverage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Intrathecal Enzyme Replacement Therapy for Spinal Cord Compression in Mucopolysaccharidosis (MPS) I
Status: TERMINATED
Conditions: Mucopolysaccharidosis I|Lysosomal Storage Diseases|Spinal Cord Compression
Interventions: DRUG: laronidase
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Detecting Traumatic Intracranial Hemorrhage With the InfraScanner 2500™ in Uganda
Status: RECRUITING
Conditions: Head Trauma|Crushing Skull Injury|Head Injury|Head Injuries, Multiple|Head Injuries, Closed|Head Trauma,Closed|Head Injury Major|Head Injury, Minor|Head Injury, Open|Injury, Craniocerebral|Injury, Head|Multiple Head Injury|Trauma, Head|Head Trauma Injury|Head Trauma, Penetrating|Craniocerebral Injury
Interventions: DEVICE: InfraScanner 2500™
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Ivabradine for Heart Rate Control In Septic Shock
Status: RECRUITING
Conditions: Septic Shock
Interventions: DRUG: Ivabradine|DRUG: Ivabradine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Antiplatelet Effect of Ticagrelor vs Tirofiban in Patients With Non-ST Elevation Acute Coronary Syndrome
Status: UNKNOWN
Conditions: Non-ST Segment Elevation Acute Coronary Syndrome
Interventions: DRUG: Tirofiban|DRUG: Ticagrelor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Different Concentrations of Sirolimus in the Treatment of Kaposiform Hemangioendothelioma.
Status: COMPLETED
Conditions: Kaposiform Hemangioendothelioma
Interventions: DRUG: Sirolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Efficacy of Less Invasive Surfactant Treatment Under Nasal CPAP and Nasal IPPV
Status: UNKNOWN
Conditions: Respiratory Distress Syndrome
Interventions: OTHER: NCPAP|OTHER: NIPPV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of TNM001 in Chinese Healthy Preterm and Term Infants
Status: COMPLETED
Conditions: Respiratory Syncytial Virus Infections
Interventions: BIOLOGICAL: TNM001|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Exercise and Body Composition in Juvenile Idiopathic Arthritis
Status: COMPLETED
Conditions: Arthritis, Juvenile
Interventions: OTHER: Ren-Ex Machine|OTHER: Dual-Emission X-ray Absorptiometry (DEXA) scan|OTHER: Biodex dynamometer|OTHER: Sub-maximal test|OTHER: Quality of life questionnaires
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: |Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Randomized, Open-label, Single-dose, Single-center, Crossover Study in Healthy Subjects to Assess the Relative Bioavailability of PT010
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Regimen A|DRUG: Regimen B|DRUG: Regimen C|DRUG: Regimen D
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Development of an in Vitro Hematopoietic Culture System and Application to Myelodysplastic Syndromes.
Status: COMPLETED
Conditions: Hematopoietic Cell Proliferation|Myelodysplastic Syndromes
Interventions: OTHER: Dynamic cultures of in vitro hematopoietic stem cells
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy of D-Cycloserine for Enhancing the Effects of CBT for Substance Use
Status: TERMINATED
Conditions: Substance-Related Disorders
Interventions: DRUG: D-cycloserine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Safety Study of BMS-852927 in Subjects With Hypercholesterolemia
Status: TERMINATED
Conditions: Hypercholesterolemia
Interventions: DRUG: BMS-852927|DRUG: BMS-852927|DRUG: BMS-852927|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Imatinib in Dermatofibrosarcoma Protuberans (DFSP)
Status: COMPLETED
Conditions: Dermatofibrosarcoma
Interventions: DRUG: Imatinib (Glivec)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Sodium Heparin (Hipolabor) in Patients
Status: COMPLETED
Conditions: Cardiac Surgery
Interventions: BIOLOGICAL: Heparin sodium Hipolabor|BIOLOGICAL: Heparin sodium APP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Trial With Gemcitabine and Rapamycin in Second Line of Metastatic Osteosarcoma
Status: COMPLETED
Conditions: Osteosarcoma
Interventions: DRUG: Gemcitabine plus rapamycin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Lymphdiaral Basistropfen (HDC) in the Treatment of Chronic Low-back Pain
Status: COMPLETED
Conditions: Low Back Pain
Interventions: DRUG: HDC|DRUG: Placebo solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Trial Of Urinary Nerve Growth Factor (NGF) As Biomarker for Male Lower Urinary Tract Symptoms
Status: COMPLETED
Conditions: Lower Urinary Tract Symptoms
Interventions: DRUG: Tamsulosin|DRUG: Solifenacin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Visualization of Rectal Cancer During Endoscopy, Using a Fluorescent Tracer
Status: COMPLETED
Conditions: Rectal Cancer
Interventions: DRUG: Bevacizumab-IRDye800CW|DEVICE: NIR fluorescence endoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Vaccine Therapy in Treating Patients With Stage IIB, Stage IIC, Stage III, or Stage IV Melanoma
Status: COMPLETED
Conditions: Intraocular Melanoma|Melanoma (Skin)
Interventions: BIOLOGICAL: mouse gp100 plasmid DNA vaccine|DEVICE: The Dermal PowderMed® devices|OTHER: intramuscularly (IM injection)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Safety and Efficacy of Cefdinir and Levofloxacin for the Treatment of Subjects With Acute Bacterial Sinusitis
Status: COMPLETED
Conditions: Acute Bacterial Sinusitis
Interventions: DRUG: cefdinir (Omnicef)|DRUG: levofloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Different Combination Chemotherapy Regimens in Treating Infants With Acute Lymphoblastic Leukemia
Status: COMPLETED
Conditions: Leukemia
Interventions: DRUG: asparaginase|DRUG: cytarabine|DRUG: mercaptopurine|DRUG: methotrexate|DRUG: prednisolone|DRUG: vincristine sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of BRAF ( B-Rapidly Accelerated Fibrosarcoma) Mutated Papillary Craniopharyngioma
Status: RECRUITING
Conditions: Craniopharyngioma
Interventions: DRUG: Oral dabrafenib and trametinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Chemotherapy and Ramucirumab Versus Chemotherapy Alone in Second Line Non-Small Cell Lung Cancer (NSCLC) Participants Who Received Prior First Line Platinum-based Chemotherapy
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer
Interventions: BIOLOGICAL: Ramucirumab|DRUG: Placebo (for Ramucirumab)|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT