pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Cabozantinib With Radiation Therapy for the Treatment of Sarcomas of the Extremities
Status: ACTIVE_NOT_RECRUITING
Conditions: Sarcoma of the Extremity|Stage I Soft Tissue Sarcoma of the Trunk and Extremities|Stage IA Soft Tissue Sarcoma of the Trunk and Extremities|Stage IB Soft Tissue Sarcoma of the Trunk and Extremities|Stage II Soft Tissue Sarcoma of the Trunk and Extremities
Interventions: DRUG: Cabozantinib S-malate|RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Galantamine Effects on Nicotine Responses in Smokers
Status: COMPLETED
Conditions: Smoking|Tobacco Withdrawal
Interventions: DRUG: Galantamine|DRUG: IV Nicotine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Living With CKD: An E-Learning Platform for Adolescents With CKD About the Disease and Its Management
Status: COMPLETED
Conditions: Chronic Kidney Diseases|Chronic Kidney Disease stage3|Chronic Kidney Disease stage4|Chronic Kidney Disease Stage V|Chronic Kidney Disease Stage 5|Chronic Kidney Disease Stage 2|Chronic Kidney Disease, Stage I|Chronic Kidney Disease, Stage IV (Severe)|Pediatric Kidney Disease
Interventions: OTHER: My Kidney Guru
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: FT819 in Subjects With B-cell Malignancies
Status: ACTIVE_NOT_RECRUITING
Conditions: Lymphoma, B-Cell|Chronic Lymphocytic Leukemia|Precursor B-Cell Acute Lymphoblastic Leukemia
Interventions: DRUG: FT819|DRUG: Cyclophosphamide|DRUG: Fludarabine|DRUG: IL-2|DRUG: Bendamustine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Of Three Different Stomach Acid Reducing Agents When Given With Palbociclib (PD-0332991) And Food
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: palbociclib commercial free base|DRUG: famotidine|DRUG: rabeprazole|DRUG: palbociclib commercial free base|DRUG: antacid|DRUG: antacid
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Persistent Pulmonary Hypertension After Percutaneous Mitral Commissurotomy
Status: UNKNOWN
Conditions: Pulmonary Hypertension
Interventions: PROCEDURE: Percutaneous Mitral Commissurotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effects of the Different Orthodontic Fixed Retainers on Enamel Colour Change
Status: UNKNOWN
Conditions: Tooth Color
Interventions: OTHER: Bond-a braid|OTHER: EverStick-Ortho|OTHER: Ribbond
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: InfasurfAero™ Versus Sham Treatment in Preterm Newborns With RDS
Status: NOT_YET_RECRUITING
Conditions: Respiratory Distress Syndrome (Neonatal)|Intubation Complication|Death; Neonatal
Interventions: COMBINATION_PRODUCT: Infasurf Aero™
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Checklist for Early Recognition and Treatment of Acute Illness (CERTAIN)
Status: COMPLETED
Conditions: Critical Illness|Sepsis|Respiratory Failure|Shock|Coma|Bleeding|Trauma
Interventions: OTHER: Checklist for Early Recognition and Treatment of Acute Illness (CERTAIN)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy and Safety of FIAsp Compared to Insulin Aspart in Combination With Insulin Glargine and Metformin in Adults With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: Faster-acting insulin aspart|DRUG: Insulin aspart|DRUG: Insulin glargine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Development of Cocktail for Measuring the Activity of Important Cytochrome P450 Enzymes
Status: TERMINATED
Conditions: Cytochrome P450 Phenotype and Genotype Metrics
Interventions: DRUG: Tramadol|DRUG: Omeprazole, losartan, caffeine|DRUG: Tramadol, omeprazole, losartan, caffeine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Efficacy and Safety of the LovenoxTM (Enoxaparin) Versus HeparinTM Gynecologic Oncology Patients
Status: SUSPENDED
Conditions: Malignant Female Reproductive System Neoplasm
Interventions: DRUG: Enoxaparin, Heparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Microcirculation and Bone Metabolism in Patients With Type 2 Diabetes Mellitus and Charcot Foot - A Pilot Study
Status: COMPLETED
Conditions: Diabetic Angiopathies|Bone Diseases, Metabolic
Interventions: OTHER: Baseline comparison of microcirculation and bone metabolism
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Double-Blind Placebo-Controlled Trial of the Safety and Immunogenicity of a Seven Valent Pneumococcal Conjugate Vaccine in Presumed HIV-Infected Infants
Status: COMPLETED
Conditions: HIV Infections|Pneumococcal Infections
Interventions: BIOLOGICAL: Pneumococcal Vaccine, Polyvalent (23-valent)|BIOLOGICAL: Pneumococcal Conjugate Vaccine, Heptavalent|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Brain Network Changes Accompanying and Predicting Responses to Pharmacotherapy in OCD
Status: RECRUITING
Conditions: Obsessive-Compulsive Disorder
Interventions: DRUG: Fluoxetine - immediate treatment|DRUG: Fluoxetine - delayed treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Multiple Ascending Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Efficacy of Bendavia™ (MTP-131) in Patients With Heart Failure
Status: WITHDRAWN
Conditions: Heart Failure
Interventions: DRUG: MTP-131|DRUG: MTP-131|DRUG: MTP-131|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of a Botanical Ingredient in Healthy Subjects With Anxiety and Poor Sleep Quality
Status: COMPLETED
Conditions: Poor Quality Sleep
Interventions: DIETARY_SUPPLEMENT: Botanical ingredient|DIETARY_SUPPLEMENT: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Developing a Clinical Outcome Assessment for Opioid Craving
Status: RECRUITING
Conditions: Opioid Craving|Opioid Use Disorder|Measure Development
Interventions: BEHAVIORAL: Neutral Cue-induced Craving|BEHAVIORAL: Visual Opioid Cue-induced Craving|BEHAVIORAL: Visual and Tactile Opioid Cue-induced Craving
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Evaluation of the Value of 18F-Fluoromisonidazole (18F-FMISO) Positron Emission Tomography Hypoxia Imaging in Idiopathic Pulmonary Fibrosis
Status: RECRUITING
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: RADIATION: FMISO-PET Protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Induction Chemotherapy in Young Patients With Locoregionally Advanced Nasopharyngeal Carcinoma
Status: UNKNOWN
Conditions: Nasopharyngeal Carcinoma|Children
Interventions: DRUG: Paclitaxel liposome|DRUG: Cisplatin|DRUG: 5-fu|RADIATION: Radical radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Infusion of Autologous T Cells Engineered to Target FSH Receptor in Recurrent Ovarian Cancer
Status: RECRUITING
Conditions: Ovarian Cancer
Interventions: DRUG: Follicle Stimulating Hormone Receptor T Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tart Cherry Juice and Markers of Inflammation, CVD, and Diabetes
Status: COMPLETED
Conditions: Hyperuricemia|Insulin Resistance|Obesity|CVD
Interventions: DIETARY_SUPPLEMENT: Tart cherry juice|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Randomised Controlled Trial to Evaluate Efficacy and Safety of Anaprazole in Patients With Duodenal Ulcers.
Status: COMPLETED
Conditions: Duodenal Ulcer，DU
Interventions: DRUG: Anaprazole Sodium|DRUG: Anaprazole Sodium|DRUG: Rabeprazole sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Enhanced Detection in Glioma Excision
Status: TERMINATED
Conditions: Glioma
Interventions: DIAGNOSTIC_TEST: Intra-operative imaging of 5-ALA fluorescence using ultra-high sensitivity camera|DIAGNOSTIC_TEST: Intra-operative imaging of 5-ALA fluorescence using in-built operative microscope camera|DIAGNOSTIC_TEST: Biopsies
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Stromal Vascular Fraction and Autologous Activated Platelet-Rich Plasma Combination in Treating Treatment of Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Platelet-rich Plasma|Stromal Vascular Fraction
Interventions: BIOLOGICAL: SVF and aaPRP
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GORE® CARDIOFORM Septal Occluder and Antiplatelet Medical Management for Reduction of Recurrent Stroke in Patients With Patent Foramen Ovale (PFO): the REDUCE Post Approval Study
Status: RECRUITING
Conditions: Stroke|PFO - Patent Foramen Ovale
Interventions: DEVICE: PFO closure with GORE® CARDIOFORM Septal Occluder
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Validation of Macimorelin as a Test for Adult Growth Hormone Deficiency
Status: COMPLETED
Conditions: Growth Hormone Deficiency With Pituitary Anomalies
Interventions: DRUG: Macimorelin|DRUG: Insulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Spinal Cord Stimulation With Precision® System Versus Reoperation for Failed Back Surgery Syndrome
Status: TERMINATED
Conditions: Failed Back Surgery Syndrome|Pain|Back Pain
Interventions: DEVICE: Precision Spinal Cord Stimulator|PROCEDURE: Back Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Efficacy and Acceptability of Antimanic Drugs in Acute Mania
Status: UNKNOWN
Conditions: Bipolar Disorder
Interventions: DRUG: Lithium|DRUG: Valproate|DRUG: Oxcarbazepine|DRUG: Quetiapine|DRUG: Olanzapine|DRUG: Ziprasidone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Kegel Exercise-focused Interventions in Elderly Women
Status: COMPLETED
Conditions: Urinary Incontinence|Kegel Exercises|Nursing
Interventions: BEHAVIORAL: Kegel exercise-focused interventions|OTHER: Home visit and scale evaluations
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Gemcitabine and Pemetrexed Disodium in Treating Patients With Advanced Mycosis Fungoides or Sézary Syndrome
Status: TERMINATED
Conditions: Lymphoma
Interventions: DRUG: Gemcitabine|DRUG: Pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Quercetin in the Treatment and Prevention of Chemotherapy-induced Neuropathic Pain in Cancer Patients
Status: WITHDRAWN
Conditions: Polyneuropathies and Other Disorders of the Peripheral Nervous System|Chemotherapy Induced Neuropathic Pain
Interventions: BEHAVIORAL: Questionnaires|DRUG: Quercetin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Ganovo （Danoprevir ） Combined With Ritonavir in the Treatment of SARS-CoV-2 Infection
Status: COMPLETED
Conditions: COVID-19
Interventions: DRUG: Ganovo+ritonavir+/-Interferon nebulization
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Different Types of Physical Training in Patients With Pulmonary Arterial Hypertension.
Status: UNKNOWN
Conditions: Pulmonary Arterial Hypertension|Cardiovascular Diseases|Respiratory Disease|Hypertension, Pulmonary|Pulmonary Hypertension
Interventions: OTHER: Physical activity
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Capoeira on the Physical and Psychological Performance of Adults
Status: ENROLLING_BY_INVITATION
Conditions: Training|Mental Health|Physical Fitness
Interventions: OTHER: CAPOEIRA TRAINING|OTHER: CONTROL GROUP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Efficacy of Inhaled Albuterol Spiromax® in Subjects With Persistent Asthma With Steady State Pharmacokinetics
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Placebo MDPI|DRUG: Albuterol MDPI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Using Game-based Exercise to Improve Balance in Cancer Patients
Status: COMPLETED
Conditions: Chemotherapy Induced Peripheral Neuropathy|Cancer
Interventions: OTHER: sensor-based interactive exercise (game-based exercise)|OTHER: Intervention without game-based exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Clinical Investigation of the Benefit: BTE Hearing Aids Versus ITE Hearing Aids
Status: COMPLETED
Conditions: Hearing Loss
Interventions: DEVICE: Mermaid 9 ITE|DEVICE: Mermaid 9 BTE
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intraarticular Pulse Radiofrequency to Treat Chronic Knee Pain
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: PROCEDURE: Unipolar pulsed radiofrequency thermocoagulation|PROCEDURE: Bipolar pulsed radiofrequency thermocoagulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: PharmacOdynamic compaRison of piTavastatin Versus atOrvastatin on Platelet Reactivity
Status: UNKNOWN
Conditions: Coronary Artery Disease
Interventions: DRUG: Atorvastatin|DRUG: Pitavastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Dose-ranging Study of Fluticasone Furoate (FF)
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Fluticasone Furoate|DRUG: Fluticasone Propionate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Amniotic Suspension Allograft in Patients With Osteoarthritis of the Knee
Status: ACTIVE_NOT_RECRUITING
Conditions: Knee Osteoarthritis
Interventions: BIOLOGICAL: Amniotic Suspension Allograft|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Combination of KD019 and Trastuzumab in Subjects With HER2-Positive Metastatic Breast Cancer
Status: TERMINATED
Conditions: HER-2 Positive Breast Cancer|Metastatic Malignant Neoplasm to Brain
Interventions: DRUG: Tesevatinib|DRUG: Trastuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ATHN 8: Previously Untreated Patients (PUPs) Matter Study
Status: COMPLETED
Conditions: Hemophilia|Hemophilia A|Hemophilia B|Hemophilia A With Inhibitor|Hemophilia B With Inhibitor|Haemophilia B Without Inhibitor|Haemophilia A Without Inhibitor|Haemophilia
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Antithrombin III Supplementation for Cardiopulmonary Bypass in Neonates
Status: TERMINATED
Conditions: Postoperative Hemorrhage
Interventions: DRUG: Antithrombin (Recombinant)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Cosmotic Outcome of Distal Penile Hypospidias Repair Using Stitch by Stitch Glanuloplasty Versus TIP
Status: COMPLETED
Conditions: Distal Penile Hypospadias
Interventions: PROCEDURE: TIP|PROCEDURE: STITCH BY STITCH
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CamTac Trial:Campath-Tacrolimus vs IL2R MoAb/Tacrolimus/MMF in Renal Transplantation
Status: COMPLETED
Conditions: Kidney Transplantation|Kidney Diseases|Kidney Failure
Interventions: DRUG: Campath|DRUG: Daclizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Dexmedetomidine vs Fentanyl for BMT
Status: COMPLETED
Conditions: Otitis
Interventions: DRUG: Saline|DRUG: Fentanyl|DRUG: Dexmedetomidine|DRUG: Dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Vaccine Therapy in Treating Patients With Kidney Cancer
Status: COMPLETED
Conditions: Kidney Cancer
Interventions: BIOLOGICAL: human prostate-specific membrane antigen plasmid DNA vaccine|BIOLOGICAL: mouse prostate-specific membrane antigen plasmid DNA vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TBTC Study 29: Rifapentine During Intensive Phase Tuberculosis (TB) Treatment
Status: COMPLETED
Conditions: Pulmonary Tuberculosis
Interventions: DRUG: rifampin|DRUG: rifapentine|DRUG: rifapentine|DRUG: rifapentine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MATCHED (MC-1 and ACE Therapeutic Combination for Hypertensive Diabetics)
Status: COMPLETED
Conditions: Diabetes Mellitus Type 2|Hypertension|Metabolic Syndrome
Interventions: DRUG: pyridoxal-5'-phosphate with and without ACE inhibitor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Allergy to Neuromuscular Blocking Agents and Pholcodine Exposure
Status: UNKNOWN
Conditions: Neuromuscular Blocking Agents Anaphylaxis
Interventions: OTHER: intradermal pholcodine allergy test in cases|OTHER: Blood sampling
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Novel Predictors of Post Spinal Hypotension in Cesarean Sections: Evaluating Jugular Vein Collapsibility Index and Shock Indices
Status: RECRUITING
Conditions: Cesarean Section Complications|Regional Anesthesia Morbidity|Hemodynamic Instability|Shock
Interventions: DIAGNOSTIC_TEST: Right Jugular Vein Collapsibility Index
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: SGLT-2i and ARB Combination Therapy in Patients With T2DM and Nocturnal Hypertension (SACRA Study)
Status: COMPLETED
Conditions: Nocturnal Hypertension|T2DM (Type 2 Diabetes Mellitus)
Interventions: DRUG: Empagliflozin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Chlorhexidine Versus Povidone-Iodine Antisepsis for Reduction of Post Cesarean Section Surgical Site Infection
Status: UNKNOWN
Conditions: Surgical Site Infection
Interventions: DRUG: Chlorhexidine|DRUG: Povidone-Iodine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: First-In-Human (FIH), Single Ascending Dose (SAD) Study of FluoroEthylNorMemantine (FENM)
Status: WITHDRAWN
Conditions: PTSD|Alzheimer Disease|Brain Diseases|Neuro-Degenerative Disease|Major Depressive Disorder|Treatment Resistant Depression
Interventions: DRUG: Fluoroethylnormemantine (FENM)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Sphenopalatine Ganglion Block for Postop Pain Management
Status: NOT_YET_RECRUITING
Conditions: Pituitary|Pain, Postoperative
Interventions: DRUG: Bupivacaine-Epinephrine 0.5%-1:200,000 Injectable Solution|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Supplementation of n-3 PUFA in the Modulation of Lean Mass in Patients With Lung Cancer Receiving a High-protein Diet
Status: RECRUITING
Conditions: Lung Cancer
Interventions: DRUG: Placebo|DRUG: Fish oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multi Interventional Study Exploring HIV-1 Residual Replication: a Step Towards HIV-1 Eradication and Sterilizing Cure
Status: COMPLETED
Conditions: Chronic Infection|HIV
Interventions: DRUG: Maraviroc|DRUG: Dolutegravir|BIOLOGICAL: Dendritic Cell Vaccine|DRUG: Auranofin|DRUG: Sirtuin Histone deacetylase inhibitor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Labour Epidural Top-up With Warmed Ropivacaine
Status: UNKNOWN
Conditions: Epidural Top-up|Labour|Caesarian Section|Ropivacaine
Interventions: OTHER: warming of ropivacaine for BT|DRUG: Ropivicaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: JT001 (VV116) for the Treatment of COVID-19
Status: COMPLETED
Conditions: Mild to Moderate COVID-19
Interventions: DRUG: JT001|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: "A Comparative Clinical Evaluation of the Efficacy of Topical Adapalene, Benzoyl Peroxide Gel, Oral Lactobacillus Rhamnosus, D-chiro-inositol, Inulin Capsule, and Their Fixed Combination in Mild to Moderate Acne Vulgaris Patients."
Status: ACTIVE_NOT_RECRUITING
Conditions: Acne Vulgaris
Interventions: DIETARY_SUPPLEMENT: Oral Lactobacillus Rhamnosus, D-chiro-inositol, Inulin Capsule|DRUG: Topical Adapalene, Benzoyl Peroxide Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low-level Laser Therapy in Wrist Fractures
Status: COMPLETED
Conditions: Colles' Fracture
Interventions: OTHER: Low level laser therapy|OTHER: Placebo Low Level Laser Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Efficacy and Safety Study of Jaktinib Hydrochloride Tablets in the Treatment of Severe Novel Coronavirus Pneumonia
Status: NOT_YET_RECRUITING
Conditions: Novel COVID-19-Infected Pneumonia
Interventions: DRUG: Jaktinib hydrochloride tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Understand How Effective is Tofacitinib When Compared to Other Advanced Treatments in Patients With Rheumatoid Arthritis
Status: ACTIVE_NOT_RECRUITING
Conditions: Rheumatoid Arthritis
Interventions: DRUG: tofacitinib|DRUG: tumor necrosis factor inhibitors (TNFi)|DRUG: abatacept|DRUG: tocilizumab or sarilumab
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Biotype Enhancing Strategy For The Patient Undergoing Accelerated Orthodontics
Status: UNKNOWN
Conditions: Class I Malocclusion|Other Periodontal Diseases|Thin Gingival Biotype
Interventions: PROCEDURE: Decortication|DEVICE: Orthodontics|DRUG: Mucograft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dosing Interval Study of SST-0225 Topical Ibuprofen Cream in the Treatment of Delayed Onset Muscle Soreness
Status: COMPLETED
Conditions: Delayed Onset Muscle Soreness
Interventions: DRUG: SST-0225|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Nasal Carbon Dioxide (CO2)for the Treatment of Temporomandibular Disorders (TMD)Related Pain
Status: COMPLETED
Conditions: Temporomandibular Disorders|Pain|Headaches
Interventions: DRUG: Nasal Carbon Dioxide|OTHER: Air
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Azithromycin Treatment for the Airway Microbiome in Asthma
Status: TERMINATED
Conditions: Asthma Chronic
Interventions: DRUG: Azithromycin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical and Translational Study of MK-0646 in Patients With Metastatic Neuroendocrine Tumors (NET)
Status: COMPLETED
Conditions: Neuroendocrine Tumors|Metastatic Neuroendocrine Tumors
Interventions: DRUG: MK-0646
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Music Therapy Model "The Bonny Method of Guided Imagery and Music" on Patients With Rheumatoid Arthritis
Status: UNKNOWN
Conditions: Rheumatoid Arthritis|Quality of Life|Chronic Pain
Interventions: OTHER: Music therapy-conversation sessions|OTHER: Discussion sessions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Strategic Training to Optimize Neurocognitive Functions in Older Adults
Status: COMPLETED
Conditions: Cognitive Aging|Functional Magnetic Resonance Imaging
Interventions: BEHAVIORAL: Low-C|BEHAVIORAL: High-C|BEHAVIORAL: High-C+
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effectiveness of a Web and Mobile Guided Psychological Intervention for Depressive Symptoms in Turkey
Status: UNKNOWN
Conditions: Depressive Symptoms
Interventions: BEHAVIORAL: Her Sey Kontrol Altinda (HSKA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Stem Cell Recruitment in Osteoporosis Therapy
Status: TERMINATED
Conditions: Low Bone Density
Interventions: DRUG: Teriparatide|DRUG: Alendronate|DIETARY_SUPPLEMENT: calcium and vitamin D
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: rTMS in First Episode Psychosis
Status: COMPLETED
Conditions: Schizophrenia|Schizophreniform Disorder|Schizoaffective Disorder
Interventions: DEVICE: rTMS|DEVICE: Sham Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dose Escalation by Boosting Radiation Dose Within the Primary Tumor Using FDG-PET-CT Scan in Stage IB, II and III NSCLC
Status: UNKNOWN
Conditions: NSCLC
Interventions: RADIATION: Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Microbiome and Sarcopenia in Patients With Liver Cirrhosis
Status: RECRUITING
Conditions: Sarcopenia|Liver Cirrhosis
Interventions: DIETARY_SUPPLEMENT: Fresubin energy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: B7.1/IL-2 Leukaemia Cell Vaccine for Non-Transplant AML RFUSIN2-AML2 (NTX)
Status: UNKNOWN
Conditions: Leukemia, Myeloid, Acute|Myelodysplastic Syndromes
Interventions: BIOLOGICAL: AML Cell Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of an Oral Growth Hormone Drug in the Treatment of Fibromyalgia
Status: COMPLETED
Conditions: Fibromyalgia
Interventions: DRUG: Ibutamoren Mesylate (MK-0677)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Clinical Outcomes After the Use of SYSTANE® HYDRATION
Status: COMPLETED
Conditions: Dry Eye
Interventions: DEVICE: SYSTANE HYDRATION lubricant eye drops|DEVICE: Hyabak 0.15% eye drops|DRUG: 0.9% saline eye drops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Efficacy and Safety of Bevacizumab Combined With PD-1 Monoclonal Antibody in Preoperative Neoadjuvant Therapy for MSS Colorectal Cancer With Liver Metastases
Status: NOT_YET_RECRUITING
Conditions: Colorectal Cancer
Interventions: DRUG: Bevacizumab Combined With PD-1 Monoclonal Antibody
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Tegaderm vs. EyeGard for Eye Protection
Status: COMPLETED
Conditions: Erythema
Interventions: DEVICE: Medical tapes: TegadermTM and EyeGard®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Methadone in Cystectomy Patients
Status: COMPLETED
Conditions: Pain, Postoperative|Postoperative Complications|Pathologic Processes|Bladder Cancer|Pain|Signs and Symptoms|Neurologic Manifestations|Neurologic Symptoms|Side Effect of Drug
Interventions: DRUG: Methadone|DRUG: Morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Atelectasis by Electrical Impedance Tomography
Status: RECRUITING
Conditions: Gynecologic Surgical Procedures|Urologic Surgical Procedures
Interventions: OTHER: Recruitment maneuver (RM)|OTHER: Reverse Trend (REV TREND)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Phase 3 Study to Evaluate the Efficacy of Lifitegrast in Subjects With Dry Eye
Status: COMPLETED
Conditions: Dry Eye Disease
Interventions: DRUG: Lifitegrast|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ROPI Study : Ropivacaine Interest in Postsurgical Pain After Mastectomy
Status: COMPLETED
Conditions: Pain After Mastectomy
Interventions: DRUG: Ropivacaine in one arm and placebo (NaCl) in the other arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Tranexamic Acid in Foot and Ankle Surgeries
Status: COMPLETED
Conditions: Foot and Ankle Surgeries|Bunion
Interventions: DRUG: Tranexamic Acid|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Obtain a Good Blood Glucose Control With the Paradigm Real Time System
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: DEVICE: Minimed paradigm Real Time Sytem|DEVICE: Minimed Paradigm 512/712 Insulin pump
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hodgkin's Disease and Chemotherapy Before 40 Years
Status: NOT_YET_RECRUITING
Conditions: Hodgkin Disease
Interventions: OTHER: Morphological and functional magnetic resonance imaging (MRI)|OTHER: Neuropsychological assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evolution of Proteomic Profiles of Intestinal Microbiota in Patients With Locally Advanced or Metastatic Urothelial Carcinomas
Status: UNKNOWN
Conditions: Urothelial Carcinoma
Interventions: BIOLOGICAL: Blood test|BIOLOGICAL: Stool sample|OTHER: Questionnaires
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Nilotinib Efficacy in Pigmented Villo-Nodular Synovitis/ Tenosynovial Giant Cell Tumour (PVNS/TGCT)
Status: COMPLETED
Conditions: Pigmented Villonodular Synovitis
Interventions: DRUG: Tasigna
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dexrazoxane Hydrochloride in Preventing Heart-Related Side Effects of Chemotherapy in Participants With Blood Cancers
Status: RECRUITING
Conditions: Acute Myeloid Leukemia|Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive|Blasts 10 Percent or More of Bone Marrow Nucleated Cells|High Risk Myelodysplastic Syndrome|Myeloid Sarcoma|Myeloproliferative Neoplasm|Philadelphia Chromosome Positive
Interventions: DRUG: Cladribine|DRUG: Cytarabine|DRUG: Dexrazoxane Hydrochloride|DRUG: Gemtuzumab Ozogamicin|DRUG: Idarubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluate the Effect of Injectable Neucardin on the Cardiac Function of Subjects With Chronic Systolic Heart Failure
Status: COMPLETED
Conditions: Chronic Systolic Heart Failure
Interventions: DRUG: Recombinant human Neuregulin for injection|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Two Tutorial Action Programs, Incidental and Structured, on the General Welfare of Elementary School Students.
Status: ACTIVE_NOT_RECRUITING
Conditions: Mental Health Wellness 1
Interventions: BEHAVIORAL: Structured emotional education program (PEE)|BEHAVIORAL: Incidental tutorial action based on the school's regular curriculum (PCO)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of Apatinib Plus Radiotherapy and S-1 for Treatment of Refractory or Metastatic Esophageal Squamous Cell Carcinoma
Status: UNKNOWN
Conditions: Refractory or Metastatic Esophageal Squamous Cell Carcinoma
Interventions: COMBINATION_PRODUCT: apatinib S-1 radiotherapy|COMBINATION_PRODUCT: S-1 radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Interactive Text-Message Based Brief Intervention to Reduce Substance-Impaired Driving Among College Students
Status: COMPLETED
Conditions: Alcohol-Impaired Driving
Interventions: BEHAVIORAL: Personalized feedback|BEHAVIORAL: Personalized feedback and text messages|BEHAVIORAL: Information Only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reduced Dissemination of Tumor Cells With Primary Ligation of the Vein in Patients With Lung Cancer
Status: UNKNOWN
Conditions: Lung Cancer|Surgery|Circulating Tumor Cell
Interventions: PROCEDURE: Vein ligation first|PROCEDURE: Artery ligation first
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Olopatadine HCl Nasal Spray in 6-11 Year Old Patients
Status: COMPLETED
Conditions: Seasonal Allergic Rhinitis
Interventions: DRUG: Olopatadine Hydrochloride Nasal Spray 0.6%|DRUG: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Capecitabine Versus Bolus 5-Fu Associated to Radiotherapy as Neoadjuvant Treatment for Rectal Cancer.
Status: COMPLETED
Conditions: Rectal Neoplasm Malignant
Interventions: DRUG: Capecitabine Oral Product|DRUG: 5Fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acalabrutinib in Patients With Relapsed/Refractory and Treatment naïve Deletion 17p CLL/SLL
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Lymphocytic Leukemia|Small Lymphocytic Lymphoma
Interventions: DRUG: Acalabrutinib (Arm A)|DRUG: Acalabrutinib (Arm B)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study To Further Evaluate The Efficacy Of Dabrafenib Plus Trametinib In Patients With Rare BRAF V600E Mutation-Positive Unresectable or Metastatic Solid Tumors
Status: RECRUITING
Conditions: Rare Unresectable or Metastatic BRAF V600E Mutation-positive Solid Tumors
Interventions: OTHER: Non-investigational
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Assessment of Er:YAG Laser for the Control of Hypersensitivity During Tooth Whitening With Hydrogen Peroxide
Status: NOT_YET_RECRUITING
Conditions: Hypersensitivity|Hypersensitivity, Immediate|Hypersensitivity Response
Interventions: PROCEDURE: Hypersensitivity prevention protocol with Er:YAG laser|PROCEDURE: Hypersensitivity prevention protocol with neutral sodium fluoride gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase Ib Study of TNO155 in Combination With Spartalizumab or Ribociclib in Selected Malignancies
Status: TERMINATED
Conditions: Non-small Cell Lung Carcinoma|Head and Neck Squamous Cell Carcinoma|Esophageal SCC|Gastrointestinal Stromal Tumors|Colorectal Cancer
Interventions: DRUG: TNO155|DRUG: Spartalizumab|DRUG: Ribociclib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant TCHP Versus THP in Patients With HER2-positive Breast Cancer (neoCARHP Study)
Status: RECRUITING
Conditions: Neoadjuvant Therapies for HER2+ Breast Cancer
Interventions: DRUG: investigator-selected taxane/carboplatin/trastuzumab/pertuzumab (TCHP)|DRUG: investigator-selected taxane/trastuzumab/pertuzumab (THP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Safety and Tolerability of Sub-retinal Transplantation of SCNT-hES-RPE Cells in Patients With Advanced Dry AMD
Status: UNKNOWN
Conditions: Dry Age Related Macular Degeneration
Interventions: DRUG: SCNT-hES-RPE Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial for Acute Severe Ulcerative Colitis
Status: RECRUITING
Conditions: Ulcerative Colitis Acute
Interventions: DRUG: Cyclosporine Injection (IV)|DRUG: Cyclosporine Oral Product|DRUG: Upadacitinib Extended Release Oral Tablet|DRUG: Intravenous Methylprednisolone|DRUG: Prednisone Oral Product
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TMC125IFD1001 - Drug-Drug Interaction of Etravirine With Telaprevir and TMC278 With Telaprevir.
Status: COMPLETED
Conditions: Hepatitis C|HIV
Interventions: DRUG: ETR/telaprevir|DRUG: TMC278/telaprevir|DRUG: telaprevir/ETR|DRUG: telaprevir/TMC278
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EMR Defaults to Nudge Opioid Prescribing
Status: COMPLETED
Conditions: Pain, Acute|Opioid Use, Unspecified
Interventions: OTHER: Default settings for opioid prescriptions (acetaminophen/hydrocodone, oxycodone, acetaminophen/oxycodone)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Assessment of Ultrasonographic Measurement of Inferior Vena Cava Collapsibility Index in Prediction of Hypotension Associated With Tourniquet Release in Total Knee Replacement Surgeries Under Spinal Anesthesia
Status: COMPLETED
Conditions: Fluid Hypovolemia, Cerebrospinal
Interventions: DIAGNOSTIC_TEST: ultrasound
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Zinc on the Gingival Crevicular Fluid Level of Total Oxidant Capacity in Type 2 Diabetic Patients
Status: UNKNOWN
Conditions: Chronic Periodontitis
Interventions: DRUG: Zinc Sulfate|PROCEDURE: scaling and root planing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ovarian Cancer Vaccine for Patients Who Have Progressed During the CAN-003 Study
Status: COMPLETED
Conditions: Epithelial Ovarian Cancer
Interventions: BIOLOGICAL: MUC1 Dendritic Cell Vaccine (Cvac)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study for the Evaluation of Safety and Tolerability of PRO-172 Ophthalmic Solution+
Status: COMPLETED
Conditions: Safety|Tolerability|Ocular Surface|Ocular Comfort
Interventions: DRUG: Bepotastine Besilate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study to Learn About the Tastes of Different Suspensions With the Study Medicine (PF-07923568) in Healthy Adult Participants.
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Sinsunatovir|OTHER: Bitrex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Calorie Reduction Or Surgery: Seeking Remission for Obesity And Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Obesity
Interventions: PROCEDURE: laparoscopic Roux-en-Y gastric bypass (RYGB) procedure|BEHAVIORAL: Lifestyle Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Telmisartan/Amlodipine Fixed Dose Combination Compared With Its Monocomponents in Healthy Male and Female Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Telmisartan/Amlodipine|DRUG: Telmisartan|DRUG: Amlodipine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testosterone, Metformin, or Both, for Hypogonadism in Obese Males
Status: COMPLETED
Conditions: Hypogonadism|Obesity
Interventions: DRUG: Placebo|DRUG: Metformin|DRUG: Testosterone Undecanoate|DRUG: Metformin + Testosterone Undecanoate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Antiemetic Effect of the Addition of Ondansetron to the Morphine Solution in Patient-Controlled Analgesia (PCA)
Status: COMPLETED
Conditions: Postoperative Nausea and Vomiting
Interventions: DRUG: ondansetron adding in PCA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Utility of Brexanolone to Target Stress-induced Alcohol Use Among Men and Women With Posttraumatic Stress Disorder
Status: RECRUITING
Conditions: PTSD|Alcohol Use Disorder
Interventions: DRUG: Brexanolone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT