pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Tarceva With Whole Brain Radiation Therapy - Brain Mets From Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer|Brain Cancer
Interventions: DRUG: Tarceva (Erlotinib hydrochloride)|RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Upper Extremity Dysfunction Post Radial Percutaneous Coronary Intervention
Status: UNKNOWN
Conditions: Upper Extremity Dysfunction
Interventions: PROCEDURE: Trans-Radial Percutaneous Coronary Intervention (TR-PCI)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparative Safety, Tolerability, Pharmacokinetic Study of AVT02 (100MG/ML) and Humira (100MG/ML) in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Adalimumab 100 MG/ML [Humira]|DRUG: AVT02 100MG/ML
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Postoperative Pain Scores and Opioid Consumption in Video Assisted Thoracic Surgery
Status: UNKNOWN
Conditions: Pain, Acute|Opioid Use
Interventions: PROCEDURE: ultrasound-guided erector spinae plane block catheter|PROCEDURE: thoracic epidural catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Low, Intermediate, or High Dose Suramin in Treating Patients With Hormone-Refractory Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: suramin|DRUG: suramin|DRUG: Suramin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Initial Resuscitation for Acute Kidney Injury in Cirrhosis
Status: NOT_YET_RECRUITING
Conditions: Cirrhosis, Liver|Acute Kidney Injury|Hepatorenal Syndrome
Interventions: OTHER: Recommendation: No Further Resuscitation|OTHER: Recommendation: Resuscitation with Crystalloid|OTHER: Recommendation: Resuscitation with Colloid|OTHER: Recommendation: Standard of Care IV Albumin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Results of Endoscopic Sinus Surgery in Management of Ophthalmological Complications of Chronic Rhino Sinusitis
Status: COMPLETED
Conditions: Chronic Sinusitis
Interventions: PROCEDURE: Endoscopic sinus evacuation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Azithromycin as a Quorum-Sensing Inhibitor for the Prevention of Pseudomonas Aeruginosa Ventilator-Associated Pneumonia
Status: TERMINATED
Conditions: Pneumonia, Ventilator-Associated|Pseudomonas Infections
Interventions: DRUG: azithromycin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Oral Rivaroxaban in Children With Venous Thrombosis
Status: COMPLETED
Conditions: Venous Thrombosis
Interventions: DRUG: Rivaroxaban (Xarelto, BAY59-7939)|DRUG: Active comparator|DRUG: Rivaroxaban (BAY59-7939) suspension
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cost-effective Treatment of Unexplained Infertility
Status: NOT_YET_RECRUITING
Conditions: Unexplained Infertility
Interventions: DRUG: Clomiphene Citrate.|DRUG: Sildenafil Citrate|PROCEDURE: Intrauterine Insemination
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immediate Surgery or Surgery After Sunitinib Malate in Treating Patients With Metastatic Kidney Cancer
Status: UNKNOWN
Conditions: Kidney Cancer
Interventions: PROCEDURE: timing of surgery|GENETIC: gene expression analysis|OTHER: biologic sample preservation procedure|OTHER: laboratory biomarker analysis|PROCEDURE: therapeutic conventional surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose-Ranging Study of the Efficacy and Safety of TAK-101 for Prevention of Gluten-Specific T Cell Activation in Participants With Celiac Disease on a Gluten-Free Diet
Status: RECRUITING
Conditions: Celiac Disease
Interventions: DRUG: Placebo|DRUG: TAK-101|DIETARY_SUPPLEMENT: Gluten
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Phase 3 Study of Barzolvolimab in Participants With Chronic Spontaneous Urticaria
Status: RECRUITING
Conditions: Chronic Spontaneous Urticaria
Interventions: BIOLOGICAL: barzolvolimab|BIOLOGICAL: Matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: One-piece and Two-piece Zirconia Abutments in Single Implant Crowns in Esthetic Region
Status: RECRUITING
Conditions: Partial-edentulism
Interventions: DEVICE: restored abutment (OPZAs)|DEVICE: restored abutment (TPZAs)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Modified Constrained - Induced Movement Therapy Compared to Intensive Bimanual Training
Status: TERMINATED
Conditions: Stroke
Interventions: BEHAVIORAL: Modified Constraint-Induced Movement therapy|BEHAVIORAL: Task-specific bimanual training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Rituximab in Treatment of Membranoproliferative Glomerulonephritis
Status: UNKNOWN
Conditions: Membranoproliferative Glomerulonephritis
Interventions: DRUG: Rituximab|DRUG: Cyclosporin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Decreasing Intakes & Absorption of Phosphorus in Haemodialysis Patients Through Food Choices
Status: COMPLETED
Conditions: Renal Dialysis|Hyperphosphatemia|Dietary Modification
Interventions: OTHER: Current Low Phosphorus Diet Prescription|OTHER: Modified Low Phosphorus Diet Prescription
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Glucosamine and Chondroitin in Gut in Preventing People From Inflammation
Status: COMPLETED
Conditions: Healthy Subject
Interventions: DIETARY_SUPPLEMENT: Glucosamine Sulfate/Chondroitin Sulfate Tablet|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effect of Light Level Applied During Breastfeeding on Maternal Stress, Anxiety, Psychological Well-being and Breastfeeding Motivation
Status: NOT_YET_RECRUITING
Conditions: Stress|Anxiety
Interventions: OTHER: Light level
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: High-Sensitivity Troponin in the Evaluation of Patients With Acute Coronary Syndrome
Status: COMPLETED
Conditions: Acute Coronary Syndrome|Myocardial Infarction
Interventions: DEVICE: High-sensitivity troponin I assay
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Single-Arm Study Evaluating Carboplatin/Gemcitabine in Combination With BSI-201 in Patients With Platinum-Sensitive Recurrent Ovarian Cancer
Status: COMPLETED
Conditions: Ovarian Cancer
Interventions: DRUG: BSI-201
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigation of the Effect of Motor Control Exercises in Patients Undergoing Rotator Cuff Surgery
Status: RECRUITING
Conditions: Rotator Cuff Tears
Interventions: OTHER: Motor control exercise|OTHER: Standard exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Persistent Pulmonary Hypertension of the Newborn (PPHN) Observational Study
Status: COMPLETED
Conditions: Infant, Newborn|Infant, Low Birth Weight|Infant, Small for Gestational Age|Infant, Premature|Persistent Fetal Circulation Syndrome|Persistent Pulmonary Hypertension of Newborn
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Assessment of the Predictive Value of the Acetic Acid Test in Surgery Condition for the Detection of Dysplastic Lesions in Patients With Anal Condylomatosis
Status: COMPLETED
Conditions: Anal Condyloma
Interventions: PROCEDURE: acetic acid test
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Pilot Pharmacokinetic Study of Daily Versus Monthly High-Dose Cholecalciferol Supplementation
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DIETARY_SUPPLEMENT: Single High Dose Cholecalciferol|DIETARY_SUPPLEMENT: Daily Dose Cholecalciferol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: PEMF Effects on Pain After Abdominal Body Contouring
Status: WITHDRAWN
Conditions: Abdominal Body Contouring Surgery|Postoperative Pain
Interventions: DEVICE: Active Device (IVIVI SofPulse)|DEVICE: Sham Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of ARNI in Patients With Persistent AF and Enlarged Left Atrium After Catheter Ablation
Status: UNKNOWN
Conditions: Atrial Fibrillation|Cardiac Remodeling, Atrial|Sacubitril/Valsartan
Interventions: DRUG: Sacubitril-Valsartan|DRUG: Valsartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BAY59-7939 Japanese in Atrial Fibrillation (2nd)
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DRUG: Xarelto (Rivaroxaban, BAY59-7939)|DRUG: Xarelto (Rivaroxaban, BAY59-7939)|DRUG: Xarelto (Rivaroxaban, BAY59-7939)|DRUG: Warfarin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Open-Label Assessment of the Albuterol Spiromax® Dry Powder Inhaler (DPI)
Status: COMPLETED
Conditions: Asthma|Chronic Obstructive Pulmonary Disease (COPD)
Interventions: DRUG: Albuterol Spiromax®
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Concentric Exercise With and Without Mulligan Wrist Mobilization After Distal Radius Fracture.
Status: UNKNOWN
Conditions: Distal Radius Fracture
Interventions: OTHER: Concentric exercises with wrist mobilization|OTHER: Concentric exercises without wrist mobilization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Explore the Individual Treatment of Docetaxel and Paclitaxel in NSCLC, NPC and BRC by PK-guided Dosing Strategy
Status: UNKNOWN
Conditions: Non-small Cell Lung Cancer|Breast Cancer|Nasal Cancer
Interventions: DEVICE: PK guided arm|DRUG: PTX 175mg/m2, DOC 75mg/m2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Exercise and Exercise Counselling in Hemodialysis Patients.
Status: UNKNOWN
Conditions: Physical Activity|Kidney Diseases|Kidney Failure|Chronic Kidney Diseases|End Stage Renal Disease
Interventions: OTHER: Functional training and cycling|OTHER: Cycling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Immunogenicity and Safety of V503 in Chinese Males 9 Through 19 Years Old (V503-053)
Status: ACTIVE_NOT_RECRUITING
Conditions: Genital Warts
Interventions: BIOLOGICAL: 9vHPV vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Early Diagnosis and Prognosis of Postoperative Sepsis by Presepsin and Syndecan-1
Status: UNKNOWN
Conditions: Sepsis Following A Procedure|Diagnoses, Syndromes, and Conditions
Interventions: DIAGNOSTIC_TEST: Quantitative determination of serum Presepsin (sCD-14), and Syndecan-1 concentrations
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of Ixekizumab (LY2439821) Compared to Guselkumab in Participants With Moderate-to-Severe Plaque Psoriasis
Status: COMPLETED
Conditions: Plaque Psoriasis
Interventions: DRUG: Ixekizumab|DRUG: Guselkumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Soy Isoflavones in Treating Patients Who Are Undergoing Radical Prostatectomy for Stage I or Stage II Adenocarcinoma of the Prostate
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DIETARY_SUPPLEMENT: soy isoflavones|PROCEDURE: neoadjuvant therapy|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effects of Evolocumab Versus Placebo Added to Standard Lipid-lowering Therapy on Fasting and Post Fat Load Lipids in Patients With Familial Dysbetalipoproteinemia
Status: UNKNOWN
Conditions: Familial Dysbetalipoproteinemia|Hyperlipoproteinemia Type III
Interventions: DRUG: Evolocumab Auto-Injector [Repatha]|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Topical Brimonidine on Post Cataract Surgery Corneal Edema
Status: UNKNOWN
Conditions: Corneal Edema|Visual Acuity
Interventions: DRUG: Brimonidine Tartrate 0.2%|DRUG: Timolol maleate 0.5%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Safety of Pulsed Radiofrequency Combined With Platelet-rich Plasma for the Trigeminal Neuralgia
Status: NOT_YET_RECRUITING
Conditions: Trigeminal Neuralgia, Idiopathic|PRP
Interventions: PROCEDURE: PRF+PRP, PRF
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effectiveness of Pimozide in Augmenting the Effects of Clozapine in the Treatment of Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia|Psychotic Disorders
Interventions: DRUG: Pimozide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1, Open-Label Evaluation of the Pharmacokinetics and Safety of a Single Dose of Apraglutide in Subjects With Normal and Impaired Hepatic Function
Status: COMPLETED
Conditions: Hepatic Impairment
Interventions: DRUG: Apraglutide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testing the Competency-based Theory of Change for Suicide Risk Among Young Male Internet Users With Societal Masculinity
Status: RECRUITING
Conditions: Self-Harm, Deliberate|Suicidal Ideation|Masculinity
Interventions: BEHAVIORAL: Competency-based physical training (CbM)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Bio-equivalence Study of Sofosbuvir From Sofodelevier 400 mg Film Coated Tablets (Al-debeiky Pharma, Egypt) Versus Sovaldi 400 mg Tablets (Gilead Sciences, Canada)
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Sofodelevier|DRUG: Sovaldi (fist dose)|DRUG: Sovaldi (second dose)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Glucose and Lipid Metabolism on Antipsychotic Medication
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder|Type 2 Diabetes Mellitus|Hyperglycemia
Interventions: DRUG: risperidone|DRUG: olanzapine|DRUG: quetiapine|DRUG: ziprasidone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diagnosis of Respiratory Viruses in Children With Rhinoswab Junior
Status: COMPLETED
Conditions: SARS CoV 2 Infection|COVID-19
Interventions: DEVICE: Rhinoswab Junior|DEVICE: Combined nose and throat swab|DEVICE: Saliva swab|DIAGNOSTIC_TEST: Abbott Panbio™ COVID-19 antigen self-test kit
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: 0.2 ml vs. 0.5 Inseminated Volume in Donor Intrauterine Insemination Cycles: A Prospective RCT
Status: COMPLETED
Conditions: Infertility|Infertility, Male|Same-Sex Marriage|Parent, Single
Interventions: PROCEDURE: Intrauterine insemination
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Does Radioiodine Treatment Prevent Atrial Fibrillation and Bone Loss in Endogenous Subclinical Hyperthyroidism?
Status: UNKNOWN
Conditions: Hyperthyroidism
Interventions: PROCEDURE: treatment with 131I
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effects of Seaweed Extract on Mental Performance Following a High-carbohydrate Meal
Status: COMPLETED
Conditions: Cognitive Change
Interventions: DIETARY_SUPPLEMENT: 500mg brown seaweed powder|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Zevalin-Containing Nonmyeloablative Conditioning for Stem Cell Transplantation (SCT)
Status: COMPLETED
Conditions: Leukemia|Lymphoma
Interventions: DRUG: Rituximab|DRUG: 111In Ibritumomab|PROCEDURE: Planar Scintigraphy Imaging|DRUG: 90Y IbritumomabTiuxetan|DRUG: Fludarabine|DRUG: Bendamustine|DRUG: Thymoglobulin|DRUG: Tacrolimus|DRUG: Methotrexate|DRUG: Mycophenolate|DRUG: G-CSF|PROCEDURE: Stem Cell Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment Patients With Pulmonary Metastasis of Liver Cancer With Apatinib Combination With TACE: a Clinical Study
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma|Pulmonary Metastasis
Interventions: DRUG: Apatinib|PROCEDURE: TACE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial to Compare Femoral Nerve Block With Local Anaesthetic Injection for Post-operative Pain After Knee Replacement.
Status: COMPLETED
Conditions: Arthritis Knee
Interventions: PROCEDURE: Femoral nerve block|PROCEDURE: Local Infiltration Analgesia|PROCEDURE: Sub arachnoid analgesia|PROCEDURE: Sedation or general anaesthesia|DRUG: Pre-medication|DRUG: Intra-operative medication|DRUG: Post-operative analgesia - morphine|DRUG: Post-operative analgesia - ibuprofen and paracetamol|DRUG: Regular anti emetics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Individualized Perioperative Open Lung Ventilatory Strategy
Status: COMPLETED
Conditions: Moderated-high Risk of Postoperative Pulmonary Complication|Abdominal Surgery Expected More Than Two Hours
Interventions: PROCEDURE: Alveolar recruitment maneuver|PROCEDURE: Calculation of optimal PEEP|PROCEDURE: Postoperative CPAP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Trial of Cytisine in Adult Smokers
Status: COMPLETED
Conditions: Smoking Cessation
Interventions: DRUG: Cytisine|DRUG: Placebo Comparator|BEHAVIORAL: Behavioral support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dutch Intracerebral Hemorrhage Surgery Trial Pilot Study
Status: COMPLETED
Conditions: Intracerebral Hemorrhage|Surgical Procedures, Minimally Invasive
Interventions: DEVICE: Minimally-invasive endoscopy-guided surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective Validation of Liver Cancer Risk Computation (LIRIC) Models
Status: ACTIVE_NOT_RECRUITING
Conditions: Predictive Cancer Model
Interventions: OTHER: Liver Risk Computation Model (LIRIC)|OTHER: Liver Risk Computation Model (LIRIC)_cirrhosis|OTHER: Liver Risk Computation Model (LIRIC)_no_cirrhosis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of the Human Anti-TNF Antibody Adalimumab for the Induction of Clinical Remission in Subjects With Crohn's Disease
Status: COMPLETED
Conditions: Crohn's Disease
Interventions: DRUG: Adalimumab (D2E7)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Non-interventional Study on Xarelto for Treatment of Venous Thromboembolism (VTE) and Prevention of Recurrent VTE in Patients With Active Cancer
Status: COMPLETED
Conditions: Venous Thrombosis and Pulmonary Embolism
Interventions: DRUG: Rivaroxaban (Xarelto, BAY 59-7939)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Adoptive Immunotherapy in Relapsed Hematological Malignancy: Early GVHD Prophylaxis
Status: COMPLETED
Conditions: Hodgkin's Lymphoma|Lymphoid Leukemia|Lymphoma|Leukemia|Myeloma|Acute Lymphocytic Leukemia|Non Hodgkin Lymphoma|Chronic Lymphocytic Leukemia|Multiple Myeloma|Chronic Myelogenous Leukemia|Myelodysplastic Syndromes|Recurrent Acute Myeloid Leukemia, Adult|Recurrent Hodgkin Lymphoma|Recurrent Non-Hodgkin Lymphoma|Recurrent Plasma Cell Myeloma|Recurrent Chronic Lymphocytic Leukemia|Recurrent Chronic Myelogenous Leukemia|Acute Myelogenous Leukemia
Interventions: DRUG: mycophenolate mofetil|BIOLOGICAL: Sargramostim|BIOLOGICAL: Filgrastim
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Is Venous to Arterial Conversion (v-TAC) of Blood Gas Reliable in Critical Ill Patients in the ICU?
Status: UNKNOWN
Conditions: Respiratory Insufficiency|Metabolic Disease|Acidosis|Alkalosis|Sepsis|Abdomen, Acute
Interventions: DIAGNOSTIC_TEST: venous to arterial conversion (v-TAC)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pre-emptive Scalp Infiltration With Dexamethasone Plus Ropivacaine for Post-Craniotomy Pain in Children
Status: COMPLETED
Conditions: Pain, Postoperative|Children
Interventions: DRUG: The dexamethasone plus ropivacaine|DRUG: The ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison Between Direct Composite and Indirect Ceramic Laminate Veneers in Multiple Diastema Closure Cases
Status: COMPLETED
Conditions: Dental Leakage
Interventions: PROCEDURE: Direct technique|PROCEDURE: Indirect technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Brigatinib in Treating Patients With ALK and ROS1 Gene Alterations and Locally Advanced or Metastatic Solid Cancers
Status: WITHDRAWN
Conditions: Advanced Malignant Neoplasm|ALK Fusion Protein Expression|ALK Gene Amplification|ALK Gene Mutation|Locally Advanced Malignant Solid Neoplasm|Metastatic Malignant Neoplasm in the Brain|Metastatic Malignant Neoplasm in the Central Nervous System|Metastatic Malignant Solid Neoplasm|ROS1 Fusion Positive|ROS1 Gene Amplification|ROS1 Gene Mutation
Interventions: DRUG: Brigatinib|OTHER: Laboratory Biomarker Analysis|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fructose and Glucose and TAS1R2 in Type 1 Diabetes
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: DIETARY_SUPPLEMENT: Glucose|DIETARY_SUPPLEMENT: Fructose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Crossover Study to Compare RAYOS to IR Prednisone to Improve Fatigue and Morning Symptoms for SLE
Status: COMPLETED
Conditions: Lupus Erythematosus, Systemic|Lupus Erythematosus|Fatigue
Interventions: DRUG: RAYOS|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: First-in-Human Study to Investigate the Safety and Tolerability and Pharmacokinetics of HS-10383
Status: UNKNOWN
Conditions: Cough
Interventions: DRUG: HS-10383|DRUG: HS-10383 Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Biomarkers and Cardiorenal Syndrome in Acute Decompensated Heart Failure With Vasodilator Therapy
Status: COMPLETED
Conditions: Acute Decompensated Heart Failure
Interventions: DRUG: Nesiritide|DRUG: Nitroglycerin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non-opioids for Analgesia After Adenotonsillectomy in Children
Status: TERMINATED
Conditions: Adenotonsillectomy|Post-operative Analgesia|Opioid Use
Interventions: DRUG: Oxycodone|DRUG: Ibuprofen|DRUG: Acetaminophen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endobronchial Valve in Patients With Heterogeneous Emphysema
Status: UNKNOWN
Conditions: Chronic Obstructive Pulmonary Disease|Emphysema
Interventions: DEVICE: Zephyr endobronchial valve placement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hepatitis B Vaccine in Seniors
Status: COMPLETED
Conditions: Hepatitis B Vaccination
Interventions: BIOLOGICAL: Subcutaneous fat injection of Recombivax-HB|BIOLOGICAL: Intramuscular injection of Recombivax-HB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Phase I Clinical Trial of DA-6886 in Healthy Male Subjects
Status: COMPLETED
Conditions: Irritable Bowel Syndrome
Interventions: DRUG: DA-6886|DRUG: Placebo of DA-6886
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Reducing Adenoviral Patient Infected Days
Status: COMPLETED
Conditions: Conjunctivitis|Adenoviral Conjunctivitis
Interventions: DRUG: Betadine 5%|DRUG: Artificial Tears
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Quantitative Ultrasound With Liver Incytes for Evaluation of Non-Alcoholic Fatty Liver Disease
Status: TERMINATED
Conditions: NAFLD|NASH - Nonalcoholic Steatohepatitis
Interventions: DIAGNOSTIC_TEST: Velacur by Sonic Incytes
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: BRIM-P: A Study of Vemurafenib in Pediatric Patients With Stage IIIC or Stage IV Melanoma Harboring BRAFV600 Mutations
Status: TERMINATED
Conditions: Malignant Melanoma
Interventions: DRUG: vemurafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Escitalopram in the Treatment of Children and Adolescents With Generalized Anxiety Disorder
Status: COMPLETED
Conditions: Anxiety Disorders,Generalized Anxiety Disorder
Interventions: DRUG: Escitalopram|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Drug Use Surveillance of Takecab for "Supplement to Helicobacter Pylori Eradication"
Status: COMPLETED
Conditions: Gastric/Duodenal Ulcer, Gastric MALT Lymphoma, Idiopathic Thrombocytopenic Purpura, or H. Pylori Gastritis, and Other
Interventions: DRUG: Vonoprazan|DRUG: Amoxicillin hydrate|DRUG: Clarithromycin|DRUG: Metronidazole
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Amnion Chorion Membrane vs. Dense Polytetrafluoroethylene Membrane in Ridge Preservation Procedures
Status: COMPLETED
Conditions: Alveolar Bone Loss|Pathological Conditions, Anatomical
Interventions: DEVICE: Placing Amnion chorion membrane over grafted site|DEVICE: Placing d-PTFE membrane over grafted site
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of FMPO in Improving the Quality of Care for Persons With Severe Mental Illness.
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder|Major Depression
Interventions: BEHAVIORAL: Family Member Provider Outreach|BEHAVIORAL: Enhanced treatment as usual (e-TAU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use of the Leva Incontinence System in Treating Bladder Incontinence.
Status: COMPLETED
Conditions: Stress Urinary Incontinence
Interventions: DEVICE: Leva Incontinence System For Pelvic Floor Muscle strengthening
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: pBFS Guided VS "5-cm Rule" rTMS Over DLPFC for MDD
Status: RECRUITING
Conditions: Major Depression|MDD
Interventions: DEVICE: pBFS rTMS|DEVICE: 5-cm rTMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparison of McGrath MAC Videolaryngoscopy and Macintosh Laryngoscopy for Orotracheal Intubation in Children
Status: COMPLETED
Conditions: Anesthesia, Endotracheal
Interventions: DEVICE: McGrath MAC videolaryngoscopy|DRUG: Macintosh Laryngoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Intrawound Vancomycin Prophylaxis for Neural Stimulator
Status: UNKNOWN
Conditions: Vancomycin|Implantable Neural Stimulator|Deep Brain Stimulation|Surgical Site Infection
Interventions: DRUG: Vancomycin Hydrochloride|DRUG: Saline Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: HA-WBRT-SIB for Brain Metastasis of Lung Cancer
Status: COMPLETED
Conditions: Lung Neoplasm|Brain Metastases|Simultaneous Integrated Boost|Hippocampal Avoidance|Cognitive Function
Interventions: RADIATION: HA-WBRT-SIB
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Application of Docozine Combined With Sufentanil for Awake Tracheal Intubation
Status: COMPLETED
Conditions: Awake Tracheal Intubation
Interventions: DRUG: Docozine|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Study of JS001 Compared to High-Dose Interferon In Patients With Mucosal Melanoma That Has Been Removed by Surgery
Status: ACTIVE_NOT_RECRUITING
Conditions: Mucosal Melanoma
Interventions: BIOLOGICAL: humanized anti-PD-1 monoclonal antibody Toripalimab|BIOLOGICAL: high-dose recombinant interferon a-2B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy Followed by Surgery in Treating Infants With Newly Diagnosed Neuroblastoma
Status: COMPLETED
Conditions: Neuroblastoma
Interventions: DRUG: carboplatin|DRUG: cyclophosphamide|DRUG: doxorubicin hydrochloride|DRUG: etoposide|DRUG: vincristine sulfate|PROCEDURE: conventional surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Effects of Rehabilitation and Kinesio Taping to Prevent Axillary Web Syndrome After Breast Cancer Surgery
Status: COMPLETED
Conditions: Axillary Web Syndrome
Interventions: OTHER: Kinesio taping, Lymphatic drainage|OTHER: Lymphatic drainage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Guided Bone Regeneration With Custom Made Meshes
Status: COMPLETED
Conditions: The Presence of Horizontal and Vertical Alveolar Defects in Both Jaws, Inadequate for the Placement of at Least Two Fixtures, Even ≤6 mm Long Ones
Interventions: DEVICE: guided bone regeneration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: |Primary Purpose: TREATMENT
Clinical trial: A Study of The Impact of Severe Hepatic Impairment on the Pharmacokinetics and Safety of Vemurafenib in BRAF V600 Mutation-Positive Cancer Participants
Status: COMPLETED
Conditions: Neoplasms
Interventions: DRUG: Vemurafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TWICE (Ezetimibe Together With Any Statin Cholesterol Enhancement)(0653-060)
Status: COMPLETED
Conditions: Hypercholesterolaemia|Hyperlipidaemia
Interventions: DRUG: MK-0653, ezetimibe|DRUG: Duration of Treatment: 3 months
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Examination of the Effects of Liraglutide on the Mode of Action of Insulin Detemir
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: liraglutide|DRUG: insulin detemir
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Venetoclax in Combination With Azacitidine Versus Azacitidine in Treatment Naïve Participants With Acute Myeloid Leukemia Who Are Ineligible for Standard Induction Therapy
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Myeloid Leukemia (AML)
Interventions: DRUG: Azacitidine|DRUG: Venetoclax|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intensive Chemotherapy and Autotransplantation for Patients With Newly Diagnosed Anaplastic Oligodendroglioma
Status: COMPLETED
Conditions: CNS Cancer|CNS BRAIN
Interventions: DRUG: temozolomide followed by high dose busulfan and thiotepa
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Hsp90 Inhibitor, STA-9090 for Relapsed or Refractory Small Cell Lung Cancer
Status: COMPLETED
Conditions: Small Cell Lung Cancer
Interventions: DRUG: STA-9090
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Prospective Registry for Patients at High-Risk for Pancreatic Cancer
Status: RECRUITING
Conditions: Pancreatic Cancer|Pancreatic Ductal Adenocarcinoma|PDAC|PDAC - Pancreatic Ductal Adenocarcinoma
Interventions: OTHER: Bio-specimen Collection: Blood|OTHER: Bio-specimen Collection: Pancreatic Juice|DIAGNOSTIC_TEST: MRI
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety Study of TroVax Alone vs. TroVax Plus Interferon Alpha in Patients With Renal Cancer
Status: COMPLETED
Conditions: Carcinoma, Renal Cell
Interventions: BIOLOGICAL: TroVax® (Immunological Vaccine Therapy)|DRUG: Interferon-alpha
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A phase3 Study Measuring the Effect of Rosuvastatin 20 mg on Carotid Intima-Media Thickness in Chinese Subjects With Subclinical Atherosclerosis
Status: COMPLETED
Conditions: Atherosclerosis
Interventions: DRUG: Rosuvastatin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mechanisms of Disuse Atrophy in Human Skeletal Muscle (iMOB)
Status: UNKNOWN
Conditions: Muscular Atrophy|Immobility Syndrome
Interventions: BEHAVIORAL: Single leg immobilisation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Prevalence and Reproductive Outcome of Infertile Women With Genital Tuberculosis
Status: UNKNOWN
Conditions: Infertility, Female|Genital Tuberculoses, Female
Interventions: DIAGNOSTIC_TEST: QuantiFERON-TB test & endometrial pathology & endometrial tissue GeneXpert Ultra
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase 2 Evaluation of Anti-VEGF Therapy for Diabetic Macular Edema: Bevacizumab (Avastin)
Status: COMPLETED
Conditions: Diabetic Retinopathy
Interventions: PROCEDURE: Laser Photocoagulation|DRUG: Bevacizumab|DRUG: Bevacizumab|DRUG: Bevacizumab|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Results From a Health System-wide Implementation of a Quality of Life Questionnaire
Status: COMPLETED
Conditions: Medical Oncology|Cardiology|Integrative Medicine|Physical and Rehabilitation Medicine|Orthopedics|Spine|Palliative Care|Pulmonary Medicine|Primary Care
Interventions: OTHER: PROMIS-10 questionnaire
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effectiveness of Almotriptan Malate (AXERT®) 12.5 Milligrams When Taken at the Onset of Migraine Pain
Status: COMPLETED
Conditions: Migraine
Interventions: DRUG: almotriptan malate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Carbon Ion Radiotherapy in Treating Patients Undergoing Systemic Therapy for Oligo-metastatic Prostate Cancer
Status: UNKNOWN
Conditions: Metastatic Prostate Carcinoma
Interventions: RADIATION: CIRT with systemic therapy arm
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Short-term Antibiotic for Pyelonephritis in Women
Status: COMPLETED
Conditions: Acute Uncomplicated Pyelonephritis
Interventions: DRUG: Ceftriaxone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transcranial Direct Current Stimulation (TDCS) as an Intervention for Patients With Traumatic Brain Injury
Status: ACTIVE_NOT_RECRUITING
Conditions: Traumatic Brain Injury
Interventions: DEVICE: Anodal Transcranial Direct Current Stimulation|DEVICE: Sham stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Single and Multiple Ascending Dose Study of CORT113176 in Healthy Participants
Status: COMPLETED
Conditions: Healthy Adults
Interventions: DRUG: CORT113176 Lipid Capsule Formulation|DRUG: Placebo matching CORT113176 Lipid Capsule Formulation|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Compare Ceftazidime-Avibactam + Metronidazole vs Meropenem for Hospitalized Adults With Complicated Intra-Abd Infections
Status: COMPLETED
Conditions: Complicated Intra-abdominal Infection
Interventions: DRUG: Ceftazidime-avibactam|DRUG: metronidazole|DRUG: Meropenem
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sensor-Augmented Insulin Delivery: Insulin Plus Glucagon Versus Insulin Alone
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: DRUG: Insulin, Asp(B28)-|DRUG: Glucagon|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Steroid-sparing Therapy (Olanzapine) Versus Dexamethasone-based Therapy for Chemotherapy-induced Nausea and Vomiting
Status: RECRUITING
Conditions: Chemotherapy-induced Nausea and Vomiting
Interventions: DRUG: OLA group: Olanzapine|DRUG: DEX group: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of Topical ABI-1968 in Subjects With Precancerous Cervical Lesions From Human Papillomavirus (HPV) Infection
Status: COMPLETED
Conditions: HSIL|HSIL of Cervix|High-Grade Squamous Intraepithelial Lesions|High-grade Cervical Intraepithelial Neoplasia|Human Papilloma Virus|Cervical Cancer|Cervical Intraepithelial Neoplasia|Cervical Neoplasm|Cervical Dysplasia|CIN
Interventions: DRUG: ABI-1968
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical And Radiographic Evaluation Of Nano-Propolis, Nano-Curcumin and MTA as Direct Pulp Capping Agents in Young Permanant Teeth
Status: RECRUITING
Conditions: Traumatic Pulp Exposure in Children
Interventions: COMBINATION_PRODUCT: MTA Cement, propolis nano particle, curcumin nanoparticles
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Aromatic Solution Applied After Surgery
Status: COMPLETED
Conditions: Surgery|Nurse's Role|Throat, Sore|Thirst|Nausea and Vomiting, Postoperative
Interventions: PROCEDURE: group treated with aromatic solution|PROCEDURE: group treated with drinking water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effectiveness of SMS-text Message Support for Patients With Hypertension to Improve Blood Pressure
Status: COMPLETED
Conditions: Hypertension|SMS-text|mHealth
Interventions: BEHAVIORAL: Informational SMS-text|BEHAVIORAL: Interactive SMS-text|BEHAVIORAL: Enhanced usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effectiveness of WBV Versus RAS on Spasticity, Balance, and Lower Limb Motor Function on Hemiplegic Stroke Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Stroke
Interventions: PROCEDURE: Vibration Therapy|COMBINATION_PRODUCT: Rhythmic auditory stimulation therapy.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Comparing Level 1 Compression Sleeves With Routine Care in Preventing Breast Cancer-related Arm Lymphedema
Status: RECRUITING
Conditions: Breast Cancer-related Arm Lymphedema
Interventions: DEVICE: compression sleeves for upper limbs with a pressure level of 1 (15-20mmHg)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Bevacizumab in Combination With 5-FU, Oxaliplatin and External Beam Radiation Followed by Gemcitabine and Bevacizumab for Locally Advanced Pancreatic Cancer
Status: TERMINATED
Conditions: Pancreatic Cancer|Pancreatic Ductal Adenocarcinoma
Interventions: DRUG: bevacizumab|DRUG: 5-Fluorouracil|DRUG: Oxaliplatin|DRUG: gemcitabine|PROCEDURE: External Beam Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Azithromycin Microspheres in Patients With Low Risk Community Acquired Pneumonia
Status: COMPLETED
Conditions: Community-Acquired Pneumonia
Interventions: DRUG: Azithromycin microspheres 2.0 single dose
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sildenafil Citrate Before Surgery in Improving Kidney Function in Patients With Kidney Cancer
Status: COMPLETED
Conditions: Kidney Tumor
Interventions: DRUG: sildenafil citrate|OTHER: placebo|PROCEDURE: therapeutic conventional surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE