pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Proof of Principle Study of Aminolevulinic Acid (ALA) - Induced Fluorescence Detection in Resectable Non-Small Cell Lung Cancer
Status: WITHDRAWN
Conditions: Lung Cancer in Normal and Malignant Tumors
Interventions: DRUG: ALA-induced Fluorescence
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: To Assess the Relative Bioavailability (BA) of TRIUMEQ® and Dolutegravir and Lamivudine (DTG/3TC) Pediatric Dispersible Tablet Formulations in Healthy Volunteers
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Treatment A|DRUG: Treatment B|DRUG: Treatment C|DRUG: Treatment D|DRUG: Treatment E|DRUG: Treatment F
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Remin Pro Forte Versus Remin Pro on Treatment of White Spot Lesions Post Orthodontic Treatment
Status: UNKNOWN
Conditions: White Spot Lesion
Interventions: COMBINATION_PRODUCT: Remin Pro Forte|COMBINATION_PRODUCT: Remin Pro
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Therapy of Anlotinib Combined With Toripalimab and Chemotherapy for Resectable Esophageal Carcinoma
Status: NOT_YET_RECRUITING
Conditions: Esophageal Carcinoma|Neoadjuvant Therapy
Interventions: DRUG: Toripalimab|DRUG: Anlotinib hydrochloride|DRUG: Albumin paclitaxel|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of High Nitrate Vegetable Juice Supplementation on Plasma Nitrate and Blood Pressure in Healthy Adults
Status: COMPLETED
Conditions: Blood Pressure
Interventions: OTHER: Food-based - beetroot juice|OTHER: Food-based - leafy green vegetable juice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Interventional Strategy for Non-culprit Lesions With Major Vulnerability Criteria at OCT in Patients With ACS
Status: RECRUITING
Conditions: Coronary Artery Disease|Coronary Disease|Ischemic Heart Disease
Interventions: DEVICE: Optical coherence tomography|DEVICE: iFR/FFR/RFR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Electro-acupuncture for the Prevention and Treatment of Oxaliplatin-induced Neurotoxicity in Colorectal Cancer Patients
Status: NOT_YET_RECRUITING
Conditions: Colorectal Cancer|Oxaliplatin|Electro-acupuncture|Neurotoxicity
Interventions: DEVICE: Acupuncture|DEVICE: Sham-acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Accelerometer-linked Online Intervention to Promote Physical Activity in Adolescents
Status: COMPLETED
Conditions: Health Behavior|Adolescent Behavior|Motivation
Interventions: BEHAVIORAL: Intervention Group (motivational website, activity meter)|BEHAVIORAL: Active Control (active video game, activity meter)|OTHER: Passive Control (activity meter)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Postpartum Pelvic Floor Muscle Training in Women With and Without Injured Pelvic Floor Muscles
Status: COMPLETED
Conditions: Urinary Incontinence
Interventions: OTHER: Postpartum pelvic floor muscle training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Dolutegravir Plus Lamivudine Dual Therapy in Treatment Naïve HIV-1 Patients
Status: COMPLETED
Conditions: HIV-1 Infection
Interventions: DRUG: Dolutegravir|DRUG: Lamivudine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Group Education Trial to Improve Transition for Parents of Adolescents With T1D
Status: ACTIVE_NOT_RECRUITING
Conditions: Diabetes Mellitus|Diabetes Mellitus, Type 1|Glucose Metabolism Disorders|Metabolic Disease|Endocrine System Diseases|Autoimmune Diseases|Immune System Diseases
Interventions: BEHAVIORAL: Group education sessions for parents plus usual diabetes care|OTHER: Usual diabetes care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comprehensive Disease Management Program in Chronic Obstructive Pulmonary Disease (COPD) Patients in the Community
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: OTHER: Disease management|OTHER: Best care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Efficacy of 10-day and 14-day Sequential Therapy Versus Triple Therapy on the Eradication of Helicobacter Pylori
Status: COMPLETED
Conditions: H. Pylori Infection
Interventions: DRUG: Sequential therapy for 14 days|DRUG: Sequential therapy for 10 days|DRUG: Triple therapy for 14 days
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing the Use of Deep or Standard Neuromuscular Blockade in Combination With Low or Standard Insufflation Pressures in Participants Undergoing Laparoscopic Cholecystectomy (P07982)
Status: COMPLETED
Conditions: Gallbladder Disease
Interventions: DRUG: Rocuronium|OTHER: Insufflation|DRUG: Sugammadex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study to Evaluate Magnetic Marker Imaging on Diabetic Polyneuropathy and Gastroparesis
Status: COMPLETED
Conditions: Diabetic Polyneuropathy|Diabetic Gastroparesis|Diabetes Mellitus
Interventions: DEVICE: Magnetic Marker Imaging (MMI) with Magma 3D system
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Health Promotion on Allergic Rhinitis by Infrared-C Ray Irradiation
Status: COMPLETED
Conditions: Allergic Rhinitis
Interventions: DEVICE: infrared-C ray irradiation|DEVICE: eye mask|DRUG: Xyzal Oral Product|DRUG: Fluticasone Furoate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: 50 Hz Repetitive Transcranial Magnetic Stimulation (rTMS) for the Treatment of Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: PROCEDURE: 50 HZ Repetitive TMS|PROCEDURE: Sham rTMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Inorganic NItrate and EXercise Performance in Heart Failure (iNIX-HF): Dose Response
Status: ACTIVE_NOT_RECRUITING
Conditions: Heart Failure
Interventions: DRUG: KNO3, potassium nitrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Patient-Controlled Sedation in Port Implantation (PACSPI-2)
Status: RECRUITING
Conditions: Pain|Patient Satisfaction|Cancer|Venous Puncture
Interventions: DRUG: Propofol + Alfentanil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess Safety, Tolerability and MTD of a Central Pattern Generator-activating Tritherapy (SPINALON) in Patients With Chronic Spinal Cord Injury
Status: COMPLETED
Conditions: Spinal Cord Injury
Interventions: DRUG: SPINALON (buspirone + levodopa + cardidopa)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Combined DEB-TACE, Lenvatinib and Pucotenlimab as Conversion Therapy for Unresectable Intrahepatic Cholangiocarcinoma
Status: RECRUITING
Conditions: Cholangiocarcinoma Non-resectable
Interventions: PROCEDURE: DEB-TACE|DRUG: Lenvatinib plus pucotenlimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Laser Acupuncture and Pelvic Floor Training on Stress Urinary Incontinence Postmenopausal
Status: UNKNOWN
Conditions: Stress|Urinary|Incontinence
Interventions: OTHER: Laser acupuncture therapy and pelvic floor training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: DEB-after-Cutting Balloon-PTA in Dialysis Fistula Stenosis
Status: UNKNOWN
Conditions: Renal Insufficiency
Interventions: DEVICE: Angioplasty with drug-coated balloon|DEVICE: Angioplasty with plain old balloon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Developing a Learning COmmunity to Increase eNgagemeNt and Enrollment in Cardiovascular Clinical Trials (CONNECT)
Status: RECRUITING
Conditions: Cardiovascular Diseases|Hypertension|Diabetes Type 2|Stroke|Recruitment|Overweight and Obesity|Hyperlipidemias
Interventions: BEHAVIORAL: EHR-informed Recruitment Method of Contact|BEHAVIORAL: Educational Text-Messages and Connection to Cardiovascular Research Opportunities
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: tDCS Interventions for Subthreshold Depressive Symptoms in Young Individuals.
Status: RECRUITING
Conditions: Subthreshold Depression|Young People|Transcranial Direct Current Stimulation
Interventions: DEVICE: tdcs lDLPFC|DEVICE: tdcs rVLPFC|DEVICE: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety & Effectiveness of TENS Weight Management Compared to a Sham
Status: COMPLETED
Conditions: Obesity, Mild
Interventions: DEVICE: TENS Active Treatment|DEVICE: Sham Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Hybrid Closure of Congenital Heart Disease
Status: COMPLETED
Conditions: Pediatric Ventricular Septal Defects
Interventions: DRUG: sufentanil anesthesia|PROCEDURE: Hybrid closure|PROCEDURE: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Ixekizumab in Participants With Active Ankylosing Spondylitis (AS)
Status: WITHDRAWN
Conditions: Spondylitis, Ankylosing
Interventions: DRUG: Ixekizumab|DRUG: Placebo|DRUG: Adalimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Efficacy and Safety of Histrelin Subdermal Implant in Men With Advanced Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer|Adenocarcinoma of the Prostate
Interventions: DRUG: histrelin acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness and Safety of Berberine Hydrochloride and Bifidobacterium in People With Abnormal Glucose Level
Status: COMPLETED
Conditions: Berberine Hydrochloride
Interventions: DRUG: Berberine Hydrochloride group|DRUG: Bifidobacterium group|DRUG: Berberine Hydrochloride and Bifidobacterium group|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: FOLFIRINOX vs FLOT Chemotherapy for Resectable Gastric or Esophagogastric Junction Adenocarcinoma
Status: RECRUITING
Conditions: Stomach Neoplasms|Gastrointestinal Neoplasms|Docetaxel|Oxaliplatin|Fluoruracil|Irinotecan Hydrochloride
Interventions: DRUG: Irinotecan|DRUG: 5-FU|DRUG: Leucovorin|DRUG: Oxaliplatin|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gemcitabine or Combination Chemotherapy Followed by Chemoradiation for Stage IB, II, or III Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DRUG: capecitabine|DRUG: cisplatin|DRUG: epirubicin hydrochloride|DRUG: fluorouracil|DRUG: gemcitabine hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of a Probiotic Mixture on the Gut Microbiome and Fatigue in Patients With Quiescent Inflammatory Bowel Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Inflammatory Bowel Diseases|Crohn Disease|Ulcerative Colitis
Interventions: DIETARY_SUPPLEMENT: Probiotic Mixture|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation of the Efficacy of an inTerdialytic "Ethanol 40% v/v - enoxapaRin 1000 U/mL" Lock solutioN to Prevent Tunnelled Catheter Infections in Chronic Hemodialysis Patients
Status: RECRUITING
Conditions: Tunnelled Hemodialysis Catheter Infection
Interventions: DRUG: Ethanol|DRUG: enoxaparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Elucidating the Neurocircuitry of Irritability With High-Field Neuroimaging to Identify Novel Therapeutic Targets
Status: RECRUITING
Conditions: Major Depressive Disorder|Healthy Controls
Interventions: DRUG: Ketamine Hydrochloride|DRUG: Midazolam injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Translational Study of MSS, TP53 Mutation and Chromosome Instability Relationship in Endometrial Carcinoma
Status: NOT_YET_RECRUITING
Conditions: Endometrial Neoplasms|TP53 Gene Mutation|Chromosomal Instability|Microsatellite Stable Endometrial Carcinoma
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Cumulative Live Birth Rates in Dual Ovarian Stimulation Versus Two Antagonist Stimulations in Poor Ovarian Responders
Status: NOT_YET_RECRUITING
Conditions: Infertility
Interventions: PROCEDURE: duostim vs. two antagonist ovarian stimulations
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Can Fecal Calprotectin Be Used as a Biomarker of Non-alcoholic Fatty Liver Disease In Obese Adolescents?
Status: COMPLETED
Conditions: Obesity, Childhood|NAFLD
Interventions: DIAGNOSTIC_TEST: Fecal Calprotectin Test
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Bevacizumab, Docetaxel, and Gemcitabine Patients With Stage IIIB, Stage IV, or Recurrent Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer
Interventions: BIOLOGICAL: bevacizumab|DRUG: docetaxel|DRUG: gemcitabine hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testing the Combination of Nivolumab and ASTX727 for Relapsed or Refractory B-Cell Lymphoma
Status: RECRUITING
Conditions: Recurrent B-Cell Non-Hodgkin Lymphoma|Recurrent Diffuse Large B-Cell Lymphoma|Recurrent Hodgkin Lymphoma|Refractory B-Cell Non-Hodgkin Lymphoma|Refractory Diffuse Large B-Cell Lymphoma|Refractory Hodgkin Lymphoma
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|DRUG: Decitabine and Cedazuridine|BIOLOGICAL: Nivolumab|PROCEDURE: Positron Emission Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of the Stability of Immediately Loaded All-on-four Dental Implants in FFF Used for Reconstruction of the Jaws
Status: COMPLETED
Conditions: Reconstructed Jaws|Free Fibula Flaps|All on Four Technique
Interventions: DEVICE: immediate loading with all on four technique in FFF
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasonographic Measurement of Diaphragmatic Thickness in Adolescents With Pectus Deformity
Status: RECRUITING
Conditions: Pectus Deformity|Pectus Excavatum|Pectus Carinatum|Pectus Abnormalities
Interventions: DIAGNOSTIC_TEST: Pectus deformity study form|DIAGNOSTIC_TEST: Pulmonary function test|DIAGNOSTIC_TEST: Ultrasonographic Diaphragm Thickness Measurement
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Supervised Exercise Training Effects on Older Community Dwellers
Status: COMPLETED
Conditions: Aging
Interventions: BEHAVIORAL: Supervised exercise training|BEHAVIORAL: Aerobic exercise training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Heart Spare the Nephron (STN) Study - A Study of CellCept (Mycophenolate Mofetil) and Rapamune (Sirolimus) in Heart Transplant Recipients
Status: TERMINATED
Conditions: Heart Transplantation
Interventions: DRUG: mycophenolate mofetil [CellCept]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Serine and Fenofibrate Study in Patients With MacTel Type 2
Status: ACTIVE_NOT_RECRUITING
Conditions: Macular Telangiectasia Type 2
Interventions: DIETARY_SUPPLEMENT: Serine|DRUG: Fenofibrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Chronic Plaque Psoriasis Study With Topical Formulation Of GW786034
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: Pazopanib|DRUG: Pazopanib vehicle|DRUG: Betamethasone valerate|DRUG: Calcipotriol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: Chemotherapy, Stem Cell Transplantation and Donor and Patient Vaccination for Treatment of Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Myeloma Immunoglobulin Idiotype Vaccine|DRUG: Bortezomib|DRUG: Cyclophosphamide|DRUG: Cyclosporine|DRUG: Doxorubicin hydrochloride|DRUG: Etoposide|DRUG: Fludarabine phosphate|DRUG: Prednisone|DRUG: Vincristine Sulfate|DRUG: Methotrexate|BIOLOGICAL: GMCSF (granulocyte macrophage colony stimulating factor)|BIOLOGICAL: GCSF (granulocyte colony stimulating factor)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability of VK2809 in Patients With Primary Hypercholesterolemia and Non-Alcoholic Fatty Liver Disease
Status: COMPLETED
Conditions: Hyperlipidemia|NAFLD
Interventions: DRUG: VK2809|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Laparoscopic Hepatectomy and Radiofrequency Ablation in the Treatment of Early Hepatocellular Carcinoma
Status: COMPLETED
Conditions: Hepatocellular Carcinoma
Interventions: PROCEDURE: Laparoscopic Hepatectomy|PROCEDURE: Radiofrequency Ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: RedStroke - Reducing Europe's Stroke Incidence
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DEVICE: App measurement|DEVICE: 14 day Holter ECG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SCREENING
Clinical trial: Effectiveness of ROTEM-based Coagulation Surveillance on Reducing Blood Product Utilization During Complex Spine Surgery
Status: TERMINATED
Conditions: Spine Surgery|Rotational Thrombo-elastometry (ROTEM)
Interventions: DEVICE: ROTEM-based coagulation monitoring|PROCEDURE: Spine surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Efficacy and Safety of Treatment With a Calcineurin Inhibitor (CNI)Versus a CNI-free Treatment in Renal Transplantation (CIME)
Status: UNKNOWN
Conditions: Kidney Failure
Interventions: DRUG: cyclosporin + mycophenolate mofetil|DRUG: everolimus + mycophenolate mofetil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Patient-Centered Intervention to Reduce Cancer Patients' Financial Toxicity
Status: COMPLETED
Conditions: Gynecologic Cancer|Colorectal Cancer|Lung Cancer
Interventions: BEHAVIORAL: I Can PIC|OTHER: Historical control survey|OTHER: Post-intervention survey (I Can PIC participants)|OTHER: Follow-Up survey (I Can PIC participants)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Clinical Performance of Prime&Bond Active in Self-etch or Selective-etch Mode With or Without Bioglass
Status: UNKNOWN
Conditions: Self-etch|Selective-etch|Bioactive Glass|Direct Resin Composite Restoration|Non-carious Cervical Lesion|Universal Adhesive
Interventions: PROCEDURE: Non-carious cervical lesion restoration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Single Rising Dose (SRD), Multiple Rising Dose (MRD) Study of BI 671800 in Healthy Asian Volunteers
Status: COMPLETED
Conditions: Asthma|Rhinitis, Allergic, Perennial
Interventions: DRUG: BI 671800|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Effect of Dietary Amino Acid Profile on Lipoprotein Metabolism, Vascular Reactivity and Inflammatory Markers
Status: COMPLETED
Conditions: Hyperlipidemias|Metabolic Syndrome X|Cardiovascular Diseases
Interventions: BEHAVIORAL: Comparison of dietary protein amino acid profile
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Enoxaparin as Treatment for Vulvodynia
Status: COMPLETED
Conditions: Vulvodynia
Interventions: DRUG: Clexane (enoxaparin)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Oral Supplementation With Curcumin on Insulin Sensitivity in Subjects With Prediabetes
Status: UNKNOWN
Conditions: PreDiabetes
Interventions: DRUG: Curcumin|DRUG: Starch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Phase I/II Study of Nilotinib/Ruxolitinb Therapy for TKI Resistant Ph-Leukemia
Status: COMPLETED
Conditions: Chronic Phase Chronic Myeloid Leukemia|Accelerated Phase Chronic Myeloid Leukemia|Blastic Phase Chronic Myeloid Leukemia|Philadelphia Positive Acute Lymphoblastic Leukemia|Resistant to Tyrosine Kinase Inhibitor Therapy
Interventions: DRUG: Nilotinib|DRUG: Ruxolitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Guanfacine Immediate-release Electrocardiogram Results (QTc) Study
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: immediate release guanfacine hydrochloride|DRUG: moxifloxacin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Antenatal Education on Knowledge,Attitude and Preferences Taward Delivery Modes
Status: NOT_YET_RECRUITING
Conditions: Antenatal Education|Modes of Delivery
Interventions: BEHAVIORAL: antenatal education
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: QLB and Laparoscopic Nephrectomy, Postoperative Pain and Recovery
Status: UNKNOWN
Conditions: Postoperative Pain|Chronic Pain Post-Proceduraal|Nausea and Vomiting, Postoperative
Interventions: DRUG: Dexamethasone sodium phosphate|DRUG: Ropivacaine Hydrocloride|DRUG: Sodium Chloride 9mg/mL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: the Efficacy and Safety of LDP in Patients With Urinary and Male Genital Tumors
Status: UNKNOWN
Conditions: Bladder Cancer|Renal Carcinoma|Advanced Penile Carcinoma
Interventions: DRUG: Human Anti-PD-L1 Monoclonal Antibody Injection (LDP)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anakinra for the Prevention of Cytokine Release Syndrome and Neurotoxicity in Patients With B-Cell Non-Hodgkin Lymphoma Receiving CD19-Targeted CAR-T Cell Therapy
Status: RECRUITING
Conditions: B-Cell Non-Hodgkin Lymphoma
Interventions: BIOLOGICAL: Anakinra|PROCEDURE: X-Ray Imaging|PROCEDURE: Positron Emission Tomography|PROCEDURE: Computed Tomography|PROCEDURE: Bone Marrow Aspiration|PROCEDURE: Bone Marrow Biopsy|PROCEDURE: Lumbar Puncture|PROCEDURE: Biospecimen Collection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Umifenovir in Hospitalized COVID-19 Patients
Status: UNKNOWN
Conditions: COVID-19
Interventions: DRUG: Umifenovir|DRUG: Interferon-β 1a|DRUG: Lopinavir / Ritonavir|DRUG: Single Dose of Hydroxychloroquine|DRUG: Standards of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Topical Bromfenac for Intraoperative Miosis and Pain Reduction
Status: UNKNOWN
Conditions: Cataract
Interventions: DRUG: 0,09% Bromfenac|DRUG: 0,1% sodium hyaluronate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacology Space Kit (PSK) - Dried Blood Spot for Caffeine Pharmacokinetics Under Microgravity Conditions
Status: COMPLETED
Conditions: Drug Mechanism|Metabolism Medication Toxicity|Space Motion Sickness
Interventions: DIAGNOSTIC_TEST: prick test
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Safety and Pharmacokinetic Study of N6022 in Subjects With Cystic Fibrosis Homozygous for the F508del-CFTR Mutation
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: N6022|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy Plus Gefitinib Followed by Chemotherapy, Radiation Therapy, and Gefitinib For Head and Neck Cancer
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: DRUG: Gefitinib|DRUG: Docetaxel|DRUG: Carboplatin|DRUG: Fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Soft Contacts Observation of Risk and Education (SCORE)
Status: COMPLETED
Conditions: Contact Lens Complication|Contact Lens Acute Red Eye|Contact Lens Related Corneal Infiltrate (Disorder)|Contact Lens-Induced Corneal Fluorescein Staining
Interventions: OTHER: No intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: SHIFT: Studying HIV Immunology After Fecal Transplant
Status: WITHDRAWN
Conditions: HIV/AIDS|Dysbiosis|Inflammation
Interventions: BIOLOGICAL: Fecal Inoculum Capsule|BIOLOGICAL: Placebo (for Fecal Inoculum Capsule)|DRUG: Antibiotic|DRUG: Antibiotic Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pharmacodynamic Biomarkers to Support Biosimilar Development: PCSK9 Inhibitors
Status: COMPLETED
Conditions: Healthy Subjects|Pharmacokinetics|Pharmacodynamics
Interventions: BIOLOGICAL: Evolocumab|BIOLOGICAL: Evolocumab|BIOLOGICAL: Evolocumab|BIOLOGICAL: Evolocumab|BIOLOGICAL: Alirocumab|BIOLOGICAL: Alirocumab|BIOLOGICAL: Alirocumab|BIOLOGICAL: Alirocumab|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Study of Camrelizumab in Combination With Apatinib Mesylate Plus Albumin-bound Paclitaxel and Cisplatin as the First Line Treatment of Recurrent or Metastatic, UnresectableHead and Neck Squamous Cell Carcinoma
Status: NOT_YET_RECRUITING
Conditions: Head and Neck Squamous Cell Carcinoma
Interventions: DRUG: Camrelizumab+Apatinib mesylate+Albumin-bound paclitaxel+cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Longitudinal Study of Music Therapy's Effectiveness for Premature Infants and Their Caregivers
Status: COMPLETED
Conditions: Preterm Birth
Interventions: BEHAVIORAL: MT during NICU|BEHAVIORAL: MT after NICU|OTHER: Standard care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SIESTA (Sleep of Inpatients: Empower Staff to Act) for Acute Stroke Rehabilitation
Status: ENROLLING_BY_INVITATION
Conditions: Sleep|Sleep Disordered Breathing|Stroke
Interventions: BEHAVIORAL: SIESTA Rehab Education|DIAGNOSTIC_TEST: ApneaLink
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Alvocidib in Treating Patients With Locally Advanced or Metastatic Solid Tumors
Status: TERMINATED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: alvocidib|OTHER: pharmacological study|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dietary Counseling or Potassium Supplement to Increase Potassium Intake in Patients With High Blood Pressure
Status: RECRUITING
Conditions: Hypertension
Interventions: BEHAVIORAL: Dietary Counselling|DRUG: Potassium Citrate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Relationship Between Insulin Resistance and Statin Induced Type 2 Diabetes, and Integrative Personal Omics Profiling
Status: COMPLETED
Conditions: Hyperlipidemia|Insulin Resistance|Type 2 Diabetes
Interventions: DRUG: Atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nocturnal Insulin-Glucose in Hospital: Tight Control
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: DEVICE: Artificial pancreas system consisting of a predictive rule-based algorithm integrated on the Medtronic Portable Glucose Control System (PGCS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: |Primary Purpose: TREATMENT
Clinical trial: Study of Tecovirimat for Human Mpox Virus
Status: RECRUITING
Conditions: MPOX
Interventions: DRUG: Tecovirimat Oral Capsule|DRUG: Placebo|DRUG: Tecovirimat Oral Capsule (Open Label)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Lenalidomide After Donor Stem Cell Transplant and Bortezomib in Treating Patients With High Risk Multiple Myeloma
Status: TERMINATED
Conditions: Refractory Multiple Myeloma|Stage I Multiple Myeloma|Stage II Multiple Myeloma|Stage III Multiple Myeloma
Interventions: DRUG: fludarabine phosphate|RADIATION: total-body irradiation|PROCEDURE: nonmyeloablative allogeneic hematopoietic stem cell transplantation|DRUG: cyclosporine|DRUG: mycophenolate mofetil|DRUG: bortezomib|DRUG: lenalidomide|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Efficacy of Aflibercept in Neovascular Age-related Macular Degeneration Patients Non Responders to Anti-Vascular Endothelial Growth Factor
Status: COMPLETED
Conditions: Wet Macular Degeneration
Interventions: DRUG: 0.5mg aflibercept
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Screening in Oculopharyngeal Muscular Dystrophy
Status: COMPLETED
Conditions: Oculopharyngeal Muscular Dystrophy
Interventions: PROCEDURE: Videofluoroscopic swallowing study|OTHER: Functional Oral Intake Scale|OTHER: Eating Assessment Tool-10
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Trial to Evaluate the Safety and Efficacy of NCR300 in Preventing Recurrence of Acute Myeloid Leukemia（AML) After Transplantation
Status: NOT_YET_RECRUITING
Conditions: Acute Myeloid Leukemia
Interventions: BIOLOGICAL: NCR300 injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Development and Testing of a Social Cognitive Theory-based Dietary Behavioral Intervention in Gastric Cancer Survivors
Status: COMPLETED
Conditions: Stomach Neoplasms|Cancer Survivors
Interventions: BEHAVIORAL: The intervention group|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Multifactorial Intervention on Diabetes (MIDiab Study)
Status: UNKNOWN
Conditions: Diabetes Mellitus, Type 2
Interventions: BEHAVIORAL: Lifestyle therapy|DRUG: Pharmacotherapy|OTHER: Monitoring and management|OTHER: General treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose-response Study of Efficacy and Safety of Botulinum Toxin Type A to Treat Spasticity of the Arm(s) or of Arm(s) and Leg(s) in Cerebral Palsy
Status: COMPLETED
Conditions: Cerebral Palsy|Spasticity
Interventions: DRUG: IncobotulinumtoxinA (8 Units per kg body weight)|DRUG: IncobotulinumtoxinA (6 Units per kg body weight)|DRUG: IncobotulinumtoxinA (2 Units per kg body weight)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I/II Study of Celebrex and EPO906 in Patients With Metastatic Colorectal Cancer
Status: UNKNOWN
Conditions: Colon Cancer|Colorectal Cancer
Interventions: DRUG: EPO906, celecoxib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 8mm-TIPS Versus Endoscopic Variceal Ligation (EVL) Plus Propranolol for Prevention of Variceal Rebleeding
Status: COMPLETED
Conditions: Portal Hypertension
Interventions: PROCEDURE: 8mm-TIPS|PROCEDURE: Endoscopic variceal ligation|DRUG: Propranolol|DEVICE: 8mm ePTFE-covered stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of V503 Given Concomitantly With Menactra™ and Adacel™ in 11 to 15 Year Olds (V503-005)
Status: COMPLETED
Conditions: Human Papillomavirus Infection
Interventions: BIOLOGICAL: V503|BIOLOGICAL: Comparator: Menactra™ (Concomitant)|BIOLOGICAL: Comparator: Adacel™ (Concomitant)|BIOLOGICAL: Comparator: Menactra™ (Non-Concomitant)|BIOLOGICAL: Comparator: Adacel™ (Non-concomitant)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Phase II, Stratified, Randomized, Double-Blind, Multi-Center Study of the Safety and Efficacy of Adefovir Dipivoxil (ADF) at Two Dose Levels in Triple Combination Therapies With Protease Inhibitors (PI) and Nucleoside Reverse Transcriptase Inhibitors (RTI) for the Treatment of HIV-Infected Patient
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Nelfinavir mesylate|DRUG: Levocarnitine|DRUG: Adefovir dipivoxil|DRUG: Saquinavir|DRUG: Lamivudine|DRUG: Stavudine|DRUG: Zidovudine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: The Insulin Response to the Gut Hormone GIP After Near-normalisation of Plasma Glucose in Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Type2 Diabetes
Interventions: OTHER: Placebo|OTHER: GIP receptor antagonization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Outcomes Of Perioperative Pregabalin On Total Knee Arthroplasty
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: DRUG: pregabalin|DRUG: Placebo|DRUG: Etoricoxib|DRUG: paracetamol|DRUG: Morphine|DRUG: Ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigation on Appropriate Duration of Dabigatran Use After Catheter Ablation for Paroxysmal Atrial Fibrillation in Patients With Low Thromboembolic Risk
Status: UNKNOWN
Conditions: Atrial Fibrillation|Thromboembolism
Interventions: DRUG: dabigatran|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Sodium Zirconium Cyclosilicate to Allow Liberal Fruit and Vegetable Intake for Patients With CKD Stage 3b and 4
Status: NOT_YET_RECRUITING
Conditions: Hyperkalemia|Diet Modification|Chronic Kidney Disease|Sodium Zirconium Cyclosilicate
Interventions: DRUG: Sodium zirconium cyclosilicate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Barbed Suture Versus Non-Barbed Suture for Posterior Colporrhaphy
Status: COMPLETED
Conditions: Rectocele
Interventions: DEVICE: 2-0 dioxanone, glycolide and trimethylene carbonate|DEVICE: 2-0 polydioxanone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Drug Eluting Balloon in peripherAl inTErvention for Below-The-Knee Arteries With Freeway and Lutonix
Status: UNKNOWN
Conditions: Peripheral Artery Disease
Interventions: DEVICE: Freeway PTA|DEVICE: Lutonix PTA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Automatic Classification of Colorectal Polyps Using Probe-based Endomicroscopy With Artificial Intelligence
Status: UNKNOWN
Conditions: Probe-based Confocal Laser Endomicroscopy|Artificial Intelligence|Colorectal Polyps
Interventions: OTHER: AI presentation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy and Safety of WPQW Granule for Overlap of NERD and IBS-D
Status: UNKNOWN
Conditions: Non-erosive Reflux Disease|Diarrhea-Predominant Irritable Bowel Syndrome
Interventions: DRUG: WPQW granule|DRUG: WPQW granule simulant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dose Escalation Study of Preoperative SBRT for High Risk Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: RADIATION: Stereotactic Body Radiation Therapy (SBRT)|PROCEDURE: Prostatectomy|OTHER: Quality of Life Questionnaires
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: a Clinical Research of Sequential CAR-T Bridging HSCT in the Treatment of Relapse/Refractory B-cell Malignancies
Status: UNKNOWN
Conditions: Lymphoma, Large B-Cell, Diffuse|Leukemia, Lymphocytic, Chronic, B-Cell|Lymphoma，Malignant
Interventions: BIOLOGICAL: CD19 or CD20 CAR T cells briging HSCT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Postorthodontic White Spot Lesions
Status: UNKNOWN
Conditions: White Spot Lesion of Tooth
Interventions: DRUG: MI varnish GC|DRUG: White varnish 3M
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: AMS AdVance and AdVance XP Male Sling Systems for the Treatment of Stress Urinary Incontinence Following Prostatectomy: Evaluation of Safety, Efficacy, and Quality of Life Through Retrospective Chart Review and Prospective Follow-up
Status: COMPLETED
Conditions: Urinary Incontinence, Stress|Intrinsic Sphincter Deficiency
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Homemade Yogurt Supplementation to Prevent Stunting
Status: COMPLETED
Conditions: Child Malnutrition
Interventions: BEHAVIORAL: Nutrition education|DIETARY_SUPPLEMENT: Homemade yogurt supplementation|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Combination Chemotherapy and Interferon Alfa-2b in Treating Patients With Nonmetastatic Liver Cancer That Cannot Be Removed by Surgery
Status: UNKNOWN
Conditions: Liver Cancer
Interventions: BIOLOGICAL: recombinant interferon alfa-2b|DRUG: doxorubicin hydrochloride|DRUG: fluorouracil|DRUG: oxaliplatin|OTHER: diagnostic laboratory biomarker analysis|OTHER: immunoenzyme technique|OTHER: immunohistochemistry staining method|PROCEDURE: adjuvant therapy|PROCEDURE: biopsy|PROCEDURE: neoadjuvant therapy|PROCEDURE: therapeutic conventional surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The INTER-CARDIO Study: The Impact of Commonly Consumed Fat on Cardiovascular Health; a Randomised Controlled Trial
Status: COMPLETED
Conditions: Healthy Adults
Interventions: DIETARY_SUPPLEMENT: Interesterified fat|DIETARY_SUPPLEMENT: Non- interesterified fat|DIETARY_SUPPLEMENT: Rapeseed oil|DIETARY_SUPPLEMENT: Butter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Music or Hypnotherapy on Cancer Patients During Chemotherapy
Status: TERMINATED
Conditions: Breast Neoplasm|Ovary Cancer
Interventions: OTHER: Interventions are self controlled by the patient via a mp3 player and noise reduction headphones.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of the Fine Structure and Temporal Envelope of the Human Cochlea in Response to Human Vocalizations
Status: RECRUITING
Conditions: Structure Cochlea|Temporal Envelope Cochlea
Interventions: PROCEDURE: near field recording of human auditory nerve activity during retro sigmoid approach with contact electrode
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Monoclonal Antibody Therapy in Treating Patients With Stage III or Stage IV Melanoma
Status: COMPLETED
Conditions: Melanoma (Skin)
Interventions: BIOLOGICAL: monoclonal antibody 4B5 anti-idiotype vaccine|BIOLOGICAL: sargramostim|DRUG: alum adjuvant
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Mechanism Based Proof of Concept Study of the Effects of Duloxetine in the Treatment of Patients With Osteoarthritic Knee Pain
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: DRUG: Duloxetine|DRUG: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Patient Preference, Sleep Quality, and Anxiety/Depression: A Randomized Comparison of Etravirine and Efavirenz
Status: COMPLETED
Conditions: Sleep Disorders
Interventions: DRUG: etravirine|DRUG: efavirenz
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: OPTIMOX-aflibercept as First-line Therapy in Patients With Unresectable Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Unresectable Metastatic Colorectal Cancer
Interventions: BIOLOGICAL: aflibercept
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT