pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Performance Evaluation of the ex Utero Cord Blood Collection Technique: Procedure, Quality and Results
Status: RECRUITING
Conditions: Umbilical Cord Blood
Interventions: PROCEDURE: Ex-utero cord blood collection|PROCEDURE: In-utero cord blood collection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Transcutaneous Electrical Nerve Stimulation (TENS) on Arterial Stiffness and Blood Pressure
Status: UNKNOWN
Conditions: Hypertension|Vascular Stiffness|Autonomic Nervous System Diseases
Interventions: DEVICE: Transcutaneous Electrical Stimulation|DEVICE: No Transcutaneous Electrical Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of tDCS in Pediatric DoC
Status: NOT_YET_RECRUITING
Conditions: Disorder of Consciousness
Interventions: DEVICE: tDCS|DEVICE: sham tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CompaRison of Paresthesia Mapping to anatomIc Midline-based burSt Programming Strategies
Status: COMPLETED
Conditions: Chronic Pain
Interventions: DEVICE: Paresthesia mapping lead evaluation first|DEVICE: Anatomical midline lead evaluation first
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Viscosupplementation for the Treatment of Knee Pain After Menisectomy
Status: WITHDRAWN
Conditions: Arthralgia
Interventions: DRUG: Hylan G-F 20|OTHER: Sham Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Test How Different Doses of BI 1815368 Are Tolerated and How BI 1815368 is Taken up in the Body of Healthy Japanese Men
Status: RECRUITING
Conditions: Healthy
Interventions: DRUG: BI 1815368|DRUG: Placebo matching BI 1815368
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Postoperative Pulmonary Complications in Robotic Versus Non-robotic Laparoscopic Surgery
Status: COMPLETED
Conditions: Postoperative Respiratory Complication
Interventions: PROCEDURE: Robot-assisted laparoscopic surgery|PROCEDURE: Conventional (non-robotic) laparoscopic surgery
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Myoelectric Activity Following Colorectal Surgery and Return of Bowel Function
Status: ENROLLING_BY_INVITATION
Conditions: Gastrointestinal Diseases|Ileus Paralytic|Ileus
Interventions: DEVICE: G-tech WPS
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparison of a Laser Keratome to a Mechanical Microkeratome
Status: COMPLETED
Conditions: Myopia|Astigmatism|Myopic Astigmatism
Interventions: DEVICE: Amadeus Microkeratome|DEVICE: IntraLase
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Improvement of Peritoneal Catheter Placement in VPS With a Splitable Trocar
Status: UNKNOWN
Conditions: Hydrocephalus
Interventions: PROCEDURE: Open Mini-Laparotomy|PROCEDURE: Abdominal Puncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CD34+ Enriched Transplants From HLA-Compatible Patients With Hematologic Malignancies
Status: WITHDRAWN
Conditions: Hematologic Diseases|Hematologic Malignancy|Acute Lymphoblastic Leukemia|Acute Myeloid Leukemia|Chronic Myelogenous Leukemia|Chronic Lymphocytic Leukemia
Interventions: DEVICE: CliniMACS|PROCEDURE: Bone Marrow Transplant|DRUG: Hyperfractionated Total Body Irradiation|DRUG: Thiotepa|DRUG: Cyclophosphamide|DRUG: Busulfan|DRUG: Melphalan|DRUG: Fludarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Relieve the Patient's Thirst, Refresh the Mouth First (ICU-MIC)
Status: COMPLETED
Conditions: Hypernatremia|Dehydration
Interventions: OTHER: Mint Ice Cube|PROCEDURE: Blood test|OTHER: Patient's questioning
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pre-meal Protein Drink Improve Glycemic Regulation
Status: TERMINATED
Conditions: Type 2 Diabetes Mellitus
Interventions: DIETARY_SUPPLEMENT: Pre-meal protein drink|OTHER: Water drink
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment Resistant Depression and Vagus Nerve Stimulation
Status: NOT_YET_RECRUITING
Conditions: Treatment Resistant Depression (TRD)
Interventions: DEVICE: Vagus Nerve Stimulation (VNS)|OTHER: Best Medical Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Prospective and Retrospective Observational Study of Multidrug-Resistant Patient Outcomes With and Without Ibalizumab
Status: RECRUITING
Conditions: HIV Infections|Multi-Antiviral Resistance
Interventions: OTHER: No ibalizumab or Pre-ibalizumab treatment|BIOLOGICAL: On ibalizumab treatment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Evaluate the Safety, Tolerability and Pharmacokinetic Properties of IN-A002 Ointment in Healthy Adult Male Volunteers and Mild to Moderate Atopic Dermatitis Patients
Status: NOT_YET_RECRUITING
Conditions: Mild to Moderate Atopic Dermatitis
Interventions: DRUG: IN-A002 Ointment 0.3% or IN-A002 Placebo Ointment|DRUG: IN-A002 Ointment 0.5% or IN-A002 Placebo Ointment|DRUG: IN-A002 Ointment 1% or IN-A002 Placebo Ointment|DRUG: IN-A002 Ointment 3% or IN-A002 Placebo Ointment|DRUG: IN-A002 Ointment 5% or IN-A002 Placebo Ointment|DRUG: IN-A002 Ointment 1%|DRUG: IN-A002 Ointment 3%|DRUG: Elidel Cream 1% (pimecrolimus)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neurofeedback of Amygdala Activity for Post-traumatic Stress Disorder
Status: TERMINATED
Conditions: Post-Traumatic Stress Disorder
Interventions: DEVICE: Experimental Feedback|DEVICE: Control Feedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Results of a Monofocal Aspheric Bitoric Intraocular Lens With Plate Haptics in Hyperopic Eyes (HIPER-AT-TORBI)
Status: COMPLETED
Conditions: Astigmatism|Far Sightedness|Cataracts
Interventions: DEVICE: Implant of the AT-TORBI 709 lens
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Validation of Criteria for Identification of Epileptiform Discharges in EEG Recordings of Patients With Epilepsy
Status: COMPLETED
Conditions: Epilepsy|Non-Epileptic Seizure
Interventions: DIAGNOSTIC_TEST: Electroencephalogram (EEG) and visual evaluation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Wearable Postural Feedback Devices Combined With Exercise in Office Workers With Chronic Neck Pain
Status: NOT_YET_RECRUITING
Conditions: Neck Pain
Interventions: DEVICE: Wearable Postural Feedback Device|OTHER: Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Type-1 Polarized Dendritic Cell (αDC1) Vaccine in Combination With Tumor-Selective Chemokine Modulation (Interferon-α2b, Rintatolimod, and Celecoxib) in Subjects With Chemo-Refractory Metastatic Colorectal Cancer
Status: WITHDRAWN
Conditions: Metastatic Colorectal Cancer
Interventions: BIOLOGICAL: αDC1 vaccine|DRUG: CKM
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Facing Your Fears in Schools: Implementing a CBT Program for Students With ASD or Other Special Learning Needs
Status: COMPLETED
Conditions: Autism Spectrum Disorder
Interventions: BEHAVIORAL: Facing Your Fears - School Based|BEHAVIORAL: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Nintedanib on Biomarkers of Extracellular Matrix Turnover in Patients With Idiopathic Pulmonary Fibrosis and Limited Forced Vital Capacity Impairment
Status: COMPLETED
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: DRUG: nintedanib|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Improve Cancer-related Cognitive Impairment
Status: NOT_YET_RECRUITING
Conditions: Gynecologic Cancer|Chemotherapy Effect|Chemo-brain|Cancer-related Cognitive Difficulties
Interventions: BEHAVIORAL: Cognitive training application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Impact of the Addition of a Device Providing Continuous Pneumatic Regulation of Tube Cuff Pressure to an Overall Strategy Aimed at Preventing Ventilator-associated Pneumonia in the Severe Trauma Patient. A Multicentre, Randomised, Controlled Study.
Status: COMPLETED
Conditions: Ventilation-associated Pneumonia|Severe Trauma Patient
Interventions: DEVICE: NOSTEN
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: |Primary Purpose: PREVENTION
Clinical trial: Clinical Application of AI-assisted Ultrasound Technology in the Preoperative Evaluation of Thyroid Cancer
Status: NOT_YET_RECRUITING
Conditions: Thyroid Cancer
Interventions: DIAGNOSTIC_TEST: Supplementary Pathological Examination|OTHER: No Need for Supplementary Pathological Examination
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluate the Efficacy of Xuebijing Injection in Acute Exacerbations of COPD
Status: UNKNOWN
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Xuebijing|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Physiotherapy and Rehabilitation Programs Following Botulinum Toxin on Children With Cerebral Palsy
Status: COMPLETED
Conditions: Cerebral Palsy
Interventions: OTHER: Goal directed physiotherapy group|OTHER: Routine physiotherapy group
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Topical Gentamicin Cream Versus Alternating Gentamicin and Mupirocin Cream in Peritoneal Dialysis
Status: UNKNOWN
Conditions: Rate of Exit Site Infection|Rate of Atypical Mycobacterial Infection|Rate of Peritoneal Dialysis
Interventions: DRUG: gentamicin|DRUG: gentamicin cream alternating with mupirocin cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of MEK162 vs. Physician's Choice Chemotherapy in Patients With Low-grade Serous Ovarian, Fallopian Tube or Peritoneal Cancer
Status: TERMINATED
Conditions: Low-grade Serous Ovarian Cancer|Low-grade Serous Fallopian Tube Cancer|Low-grade Serous Peritoneal Cancer
Interventions: DRUG: MEK162, MEK inhibitor; oral|DRUG: Physician's choice chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Test of Nutritional Interventions to Enhance Weight Loss Maintenance
Status: COMPLETED
Conditions: Overweight|Obesity|Weight Loss Maintenance
Interventions: BEHAVIORAL: Behavior Therapy|DIETARY_SUPPLEMENT: Meal Replacements|BEHAVIORAL: Nutritrol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Bictegravir/Emtricitavine/Tenofovir Alafenamide in HIV-1 Infected naïve Patients Using Test and Treat Stategy Rapid-initiation Model of Care: BIC-NOW Clinical Trial (BIC-NOW)
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: BIC/FTC/TAF
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CSD170501: Study to Assess Biomarkers of Tobacco Exposure in Smokers During In-Clinic Confinement Switch to an Electronic Cigarette
Status: COMPLETED
Conditions: Smoking
Interventions: OTHER: FT21039|OTHER: FT21092|OTHER: FT21018
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Carboplatin and Paclitaxel Combined With Cetuximab and/or IMC-A12 in Patients With Advanced Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Recurrent Non-small Cell Lung Cancer|Stage IIIB Non-small Cell Lung Cancer|Stage IV Non-small Cell Lung Cancer
Interventions: BIOLOGICAL: cixutumumab|DRUG: carboplatin|DRUG: paclitaxel|BIOLOGICAL: cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Monoclonal Antibody Treatment for Systemic Lupus Erythematosus
Status: COMPLETED
Conditions: Systemic Lupus Erythematosus
Interventions: DRUG: MRA 003 US
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of JINLINGGUAN and TOFER Formula in Formula-fed Chinese Term Infants
Status: UNKNOWN
Conditions: Infant Formula Intolerance|Well-being
Interventions: OTHER: JINLINGGUAN Infant formula,PRO-KIDO™ I-PROTECH®|OTHER: TOFER Infant formula,TOFER®|OTHER: Breast milk
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of Pembrolizumab Plus Local Chemotherapy Using Isolated Limb Infusion (ILI) for Patients With Sarcoma in the Arm or Leg
Status: RECRUITING
Conditions: Sarcoma|Myxofibrosarcoma|Undifferentiated Pleomorphic Sarcoma|Alveolar Soft Part Sarcoma
Interventions: PROCEDURE: Isolated Limb Infusion|DRUG: Pembrolizumab|DRUG: infusion of melphalan and dactinomycin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Personalized Integrated Alcohol and Sexual Assault Prevention Among College Students
Status: ENROLLING_BY_INVITATION
Conditions: Alcohol Drinking|Sexual Assault
Interventions: BEHAVIORAL: Positive Change (+Change)|BEHAVIORAL: A healthy lifestyles attention control|BEHAVIORAL: Positive Change (+Change) Plus Booster
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Aromatherapy Massage on Pain, Anxiety and Comfort
Status: RECRUITING
Conditions: Respiratory Insufficiency|Pulmonary Disease, Chronic Obstructive|Diabetes Mellitus, Type 2|High Blood Pressure|Stroke, Ischemic
Interventions: OTHER: Effect of aromatherapy massage on vital signs, pain, anxiety and comfort level
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Induction of Sustained Unresponsiveness to Peanuts Using High- and Low-dose Peanut Oral Immunotherapy
Status: RECRUITING
Conditions: Peanut Allergy
Interventions: DIETARY_SUPPLEMENT: High dose OIT|DIETARY_SUPPLEMENT: Low dose OIT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of PTX-9908 Injection for Non-resectable HCC With TACE
Status: RECRUITING
Conditions: Carcinoma, Hepatocellular
Interventions: DRUG: PTX-9908 Injection|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of AB1010 in Patients With Systemic Indolent Mastocytosis
Status: COMPLETED
Conditions: Mastocytosis
Interventions: DRUG: masitinib (AB1010)|DRUG: masitinib (AB1010)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Safety, Tolerability and Pharmacokinetic of ND-003 Tablets in Healthy Adults
Status: ENROLLING_BY_INVITATION
Conditions: Healthy
Interventions: DRUG: ND-003 40mg|DRUG: ND-003 placebo 40mg|DRUG: ND-003 80mg|DRUG: ND-003 placebo 80mg|DRUG: ND-003 160mg|DRUG: ND-003 placebo 160mg|DRUG: ND-003 240mg|DRUG: ND-003 placebo 240mg|DRUG: ND-003 300mg|DRUG: ND-003 placebo 300mg|DRUG: MAD_ND003_Dose 1|DRUG: MAD_placebo_Dose 1|DRUG: MAD_ND003_Dose 2|DRUG: MAD_placebo_Dose 2|DRUG: MAD_ND003_Dose 3|DRUG: MAD_ placebo_Dose 3|DRUG: Food effect_Cohort 1|DRUG: Food effect_Cohort 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Double Wire Technique With Pancreatic Duct Stent Placement for Difficult Bile Duct Cannulation
Status: COMPLETED
Conditions: Endoscopic Retrograde Cholangiopancreatography (ERCP)|Bile Duct Cannulation
Interventions: PROCEDURE: Pancreatic duct stent|PROCEDURE: Pancreatic wire placement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effects of Donepezil and Memantine on Cognitive Functions After a Sleep Deprivation Challenge in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Modafinil|DRUG: Donepezil|DRUG: Memantine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Lifting and Tightening of the Face and Neck Utilizing the Ulthera® System
Status: COMPLETED
Conditions: Facial and Neck Skin Laxity
Interventions: DEVICE: Ulthera® System treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Immunogenicity of Oral Polio Vaccine Type 2 in Infants and Children
Status: COMPLETED
Conditions: Adverse Event Following Immunisation
Interventions: BIOLOGICAL: SABIN monovalent OPV2
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Assessment of the Safety and Tolerability of ex Vivo Next-generation Neoantigen-selected Tumor-infiltrating Lymphocyte (TIL) Therapy in Advanced Epithelial Tumors and Immune Checkpoint Blockade (ICB) Resistant Solid Tumors
Status: RECRUITING
Conditions: Epithelial Tumors, Malignant|Malignant Solid Tumor
Interventions: BIOLOGICAL: NEXTGEN-TIL|DRUG: Non-myeloablative Lymphodepletion (NMA-LD) Regimen|DRUG: Interleukin-2
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study on The Efficacy and Safety of Vonoprazan-containing Berberine Triple Therapy in Helicobacter Pylori First-Line Eradication
Status: NOT_YET_RECRUITING
Conditions: Helicobacter Pylori Infection|Chronic Gastritis
Interventions: DRUG: Berberine|DRUG: Vonoprazan|DRUG: Amoxicillin|DRUG: Bismuth|DRUG: Clarithromycin|DRUG: Esomeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Emotional Freedom Technique and Virtual Reality Glasses on Anxiety and Vital Signs
Status: NOT_YET_RECRUITING
Conditions: Anxiety
Interventions: OTHER: Emotional Freedom Technique|OTHER: Virtual Reality Glasses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Assess the Effect of Rho-Kinase Inhibitor AR-12286 Ophthalmic Solution 0.5% and 0.7% in Patients With Chronic Angle-closure Glaucoma
Status: UNKNOWN
Conditions: Chronic Angle-closure Glaucoma
Interventions: DRUG: Rho-Kinase Inhibitor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Rectal Indomethacin vs Intravenous Ketorolac
Status: RECRUITING
Conditions: Post-ERCP Acute Pancreatitis
Interventions: DRUG: Rectal indomethacin|DRUG: IV ketorolac
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: PACE-PC: Primary Care Management of Adolescent Obesity
Status: COMPLETED
Conditions: Obesity|Overweight|Weight Loss
Interventions: BEHAVIORAL: Physician Counseling|BEHAVIORAL: Health Educator|BEHAVIORAL: Phone Counseling|BEHAVIORAL: Health promotion materials on physical activity and nutrition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Investigation of Underlying Mechanism of Lumbar Multifidus Muscle Activation Deficits
Status: COMPLETED
Conditions: Low Back Pain
Interventions: DEVICE: Transcranial magnetic stimulation|DEVICE: Neuromuscular electrical stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I Study in Asthma Patients Evaluating the Effect of Doses of FlutiForm™ on the Amount, if Any, of Cortisol Produced by the Adrenal Glands
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: FlutiForm 250/10 ug|DRUG: FlutiForm 100/10 ug|DRUG: Oral Prednisone 10mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Telomerase Activity in Endometrial Tissue and Serum in Endometriosis Patients
Status: COMPLETED
Conditions: Endometriosis Ovaries|Infertility, Female
Interventions: PROCEDURE: Cystectomy|PROCEDURE: Endometrial sampling|PROCEDURE: Peripheric blood sampling|PROCEDURE: Ovarian tissue sampling
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study To Assess The Clinical Benefit Of Droxidopa And Droxidopa/Carbidopa In Subjects With Fibromyalgia
Status: COMPLETED
Conditions: Fibromyalgia
Interventions: DRUG: Droxidopa|DRUG: Carbidopa|DRUG: Droxidopa/carbidopa|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison Between CHF5993 pMDI 200/6/12,5mg HFA-152a VS CHF5993 pMDI 200/6/12,5mg HFA-134a in Subjects With Asthma (Trecos)
Status: RECRUITING
Conditions: Asthma
Interventions: DRUG: CHF5993 200/6/12.5 μg pMDI HFA-152a|DRUG: Inhaler CHF5993 200/6/12.5 μg pMDI HFA-134a
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Lowering Dialysate Sodium in Hypertensive Hemodialysis Patients
Status: COMPLETED
Conditions: Hypertension|Arteriosclerosis|Left Ventricular Hypertrophy
Interventions: OTHER: Decreasing dialysate sodium from 138 mmol/L to 136 mmol/L
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Topical Tranexamic Acid and Floseal® in Total Knee Arthroplasty
Status: UNKNOWN
Conditions: Osteoarthritis, Knee
Interventions: DRUG: Topical tranexamic acid|DRUG: Floseal®|DRUG: Enoxaparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: The Impact of Antimicrobial Treatment for Asymptomatic Bacteriuria in Renal Transplant Patients
Status: UNKNOWN
Conditions: Urinary Tract Infection|Bacteriuria|Renal Transplantation
Interventions: OTHER: antimicrobial treatment according to in-vitro susceptibility
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Sorafenib, Lenalidomide, and Dexamethasone in Treating Patients With Relapsed or Refractory Multiple Myeloma
Status: TERMINATED
Conditions: Multiple Myeloma and Plasma Cell Neoplasm
Interventions: DRUG: dexamethasone|DRUG: sorafenib tosylate|DRUG: Lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cognitive Rehabilitation and Exposure-based Class for Compulsive Hoarding
Status: ACTIVE_NOT_RECRUITING
Conditions: Hoarding Disorder
Interventions: BEHAVIORAL: Cognitive Rehabilitation and Exposure-based Class for Compulsive Hoarding
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Camrelizumab Plus Chemotherapy vs Placebo Plus Chemotherapy as Neoadjuvant Therapy in Participants With Triple Negative Breast Cancer (TNBC)
Status: COMPLETED
Conditions: Triple Negative Breast Cancer
Interventions: DRUG: Camrelizumab Plus Chemotherapy|DRUG: placebo+chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Telitacicept for the Treatment of Moderately to Severely Active Systemic Lupus Erythematosus (REMESLE-1)
Status: RECRUITING
Conditions: Systemic Lupus Erythematosus
Interventions: DRUG: Telitacicept|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Osteoinductivity of Atorvastatin Combined With β-TCP
Status: NOT_YET_RECRUITING
Conditions: Infection|Bone Loss
Interventions: PROCEDURE: Cyst enucleation and bone grafting
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation and Implementation of an mHealth Intervention Called Mami-educ to Fight Against Gestational Obesity
Status: RECRUITING
Conditions: Gestational Weight Gain|Obesity, Maternal
Interventions: OTHER: mami-educ
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Pilot Study of Denosumab in BRCA1/2 Mutation Carriers Scheduled for Risk-Reducing Salpingo-Oophorectomy
Status: TERMINATED
Conditions: Ovarian Carcinoma
Interventions: BIOLOGICAL: Denosumab|PROCEDURE: Salpingo-Oophorectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to Test Whether BI 767551 Can Prevent COVID-19 in People Who Have Been Exposed to SARS-CoV-2
Status: WITHDRAWN
Conditions: COVID-19
Interventions: DRUG: BI 767551 intravenous|DRUG: BI 767551 inhalation|DRUG: Placebo intravenous|DRUG: Placebo inhalation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Machine Learning-based Models in Prediction of DVT and PTE in AECOPD Patients
Status: RECRUITING
Conditions: Machine Learning|Chronic Obstructive Pulmonary Disease|Chronic Obstructive Pulmonary Disease With Acute Exacerbation, Unspecified|Pulmonary Thromboembolisms|Deep Vein Thrombosis
Interventions: OTHER: Machine learning-based prediction model
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study in Subjects With Late Prodromal & Early Manifest HD to Assess the Safety, Tolerability, pk, and Efficacy of Pepi
Status: COMPLETED
Conditions: Huntington's Disease
Interventions: DRUG: VX15/2503|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MamaConecta: Digital Tool for Maternal Mental Health
Status: NOT_YET_RECRUITING
Conditions: Pregnancy Related|Mental Health Issue|Postpartum Depression|Postpartum Anxiety|Well-Being, Psychological
Interventions: OTHER: Mobile application|OTHER: Monitoring via wearable
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Respiratory Challenge on the BOLD Signal
Status: ENROLLING_BY_INVITATION
Conditions: Hypoxia, Brain|Hyperoxia|Hypercapnia|Hypocapnia
Interventions: OTHER: Carbon Dioxide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: MassCONECT (Massachusetts Community Networks to Eliminate Cancer Disparities Through Education) 4 Kids: Promoting Smoke-free Homes
Status: COMPLETED
Conditions: Tobacco Smoking Behavior
Interventions: BEHAVIORAL: Motivational Interview|BEHAVIORAL: Usual best practices
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cognitive Frailty in Older Adults: The Role of Technology in Physical Activity Enhancement
Status: UNKNOWN
Conditions: Mild Cognitive Impairment|Frailty
Interventions: DEVICE: Mobile phone application and smart watch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Clinical and Comparative Evaluation of the Treatment Results of Arthroscopic Reconstruction of Cartilage Defects in the Knee Joint With the Use of Autogenous Cartilage Graft With PRP GF (Platelet-rich Plasma With Growth Factors)
Status: UNKNOWN
Conditions: Cartilage Damage|Cartilage Injury|Knee Injuries
Interventions: PROCEDURE: Arthroscopic reconstruction of cartilage defects in the knee joint with the use of autogenous cartilage transplant with PRP GF (platelet plasma with growth factor)|PROCEDURE: Arthroscopic reconstruction of the cartilage defects of the knee joint using the microfracture method
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Long-Term Versus Short-Term Treatment of Generalized Anxiety Disorder With Venlafaxine XR
Status: COMPLETED
Conditions: Anxiety Disorders
Interventions: DRUG: Venlafaxine XR|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I/II Study Evaluating AUTO4 in Patients With TRBC1 Positive T Cell Lymphoma
Status: RECRUITING
Conditions: T Cell Non-Hodgkin Lymphoma|Peripheral T-Cell Lymphoma, Not Otherwise Specified|Angioimmunoblastic T-cell Lymphoma|Anaplastic Large Cell Lymphoma
Interventions: BIOLOGICAL: AUTO4
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Nilotinib on Safety, Tolerability, Pharmacokinetics and Biomarkers in Dementia With Lewy Bodies
Status: RECRUITING
Conditions: Dementia With Lewy Bodies
Interventions: DRUG: Placebo oral capsule|DRUG: Nilotinib Oral Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of GDT in Robot-assisted Laparoscopic Urological Surgery for Low to Moderate Risk Patients
Status: WITHDRAWN
Conditions: Vascular Hypotension|Hypovolemia|Hypervolemia
Interventions: OTHER: Control Group|OTHER: Treatment Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Concurrent Chemoradiotherapy With Famitinib for Patients With Locally Advanced Nasopharyngeal Carcinoma
Status: COMPLETED
Conditions: Locally Advanced Nasopharyngeal Carcinoma
Interventions: DRUG: Famitinib|DRUG: Cisplatin|RADIATION: radiation（IMRT）
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PK/PD of EA-230 During Endotoxemia
Status: COMPLETED
Conditions: Endotoxemia|Systemic Inflammatory Response
Interventions: DRUG: EA-230|DRUG: Endotoxin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effectiveness of Platelet Rich Plasma in Wound Healing
Status: COMPLETED
Conditions: Impacted Third Molar Tooth
Interventions: DRUG: Local anesthesia|PROCEDURE: surgical extraction of impacted third molar|BIOLOGICAL: Preparation of PRP gel|PROCEDURE: Placing platelet Rich plasma and suturing|PROCEDURE: Suturing|DRUG: Postoperative medication
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vaccine Therapy in Treating Patients With Stage II Melanoma That Can Be Removed by Surgery
Status: COMPLETED
Conditions: Melanoma (Skin)
Interventions: BIOLOGICAL: gp100 antigen|BIOLOGICAL: incomplete Freund's adjuvant|BIOLOGICAL: sargramostim|BIOLOGICAL: tyrosinase peptide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Acute Probiotic Supplementation and Endothelial Function
Status: COMPLETED
Conditions: Coronary Artery Disease|Hypertension|Hyperlipidemias|Peripheral Vascular Diseases|Cerebral Arterial Diseases
Interventions: DIETARY_SUPPLEMENT: Goodbelly|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Nivolumab in Combination With Ipilimumab Versus Nivolumab in Combination With Ipilimumab Placebo in Patients With Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: BIOLOGICAL: Nivolumab|BIOLOGICAL: Ipilimumab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of TRK-700 in Patient With Post-Herpetic Neuralgia
Status: COMPLETED
Conditions: Post-Herpetic Neuralgia
Interventions: DRUG: TRK-700|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ligation of Intersphincteric Track (LIFT) Versus Fistulectomy in Trans-sphincteric Anal Ffistula.
Status: COMPLETED
Conditions: Transsphincteric Anal Fistula
Interventions: PROCEDURE: LIFT|PROCEDURE: fistulectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment Study Comparing UVA-1 Phototherapy Versus Placebo Treatment for Morphea
Status: COMPLETED
Conditions: Scleroderma, Localized|Morphea|Scleroderma, Circumscribed
Interventions: PROCEDURE: UVA-1 Phototherapy|PROCEDURE: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: TCM Clinical Practice Rehabilitation of Post-stroke Spasticity
Status: UNKNOWN
Conditions: Stroke
Interventions: OTHER: Modern rehabilitation treatment|OTHER: Modern rehabilitation &TCM|OTHER: modern rehabilitation &Baimai Ruangao|OTHER: modern rehabilitation &Tibetan medicine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Beet-root Juice and PBM Treatments on Muscle Fatigue
Status: RECRUITING
Conditions: Health Care Utilization|Healthy Aging
Interventions: DIETARY_SUPPLEMENT: Beet-root juice|RADIATION: red-light therapy|DIETARY_SUPPLEMENT: Placebo|RADIATION: sham light
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Perioperative Analgesia by Femoral Perineural Catheter for Femoral Neck Fracture - Study KTcol
Status: COMPLETED
Conditions: Femoral Neck Fracture
Interventions: DRUG: ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study to Evaluate the Maximum Maxillary Bite Force (BF) When Using Two Novel Denture Adhesives Compared to Using No-Adhesive
Status: COMPLETED
Conditions: Denture Retention
Interventions: DEVICE: Super Poligrip Free|DEVICE: Experimental Denture Adhesive 1|DEVICE: Experimental Denture Adhesive 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: A Three-part Study of Eltrombopag in Thrombocytopenic Subjects With Myelodysplastic Syndromes or Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Thrombocytopaenia
Interventions: DRUG: eltrombopag|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Using Cranial Nerve Non-invasive Neuromodulation to Improve Pain and Upper Extremity Function After a Stroke
Status: COMPLETED
Conditions: Stroke
Interventions: PROCEDURE: Strength training intervention|PROCEDURE: Cranial nerve non-invasive neuromodulation (CN-NINM)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adefovir Dipivoxil For The Treatment Of Chinese Compensated Chronic Hepatitis B(CHB)Patients
Status: COMPLETED
Conditions: Chronic Hepatitis B
Interventions: DRUG: adefovir dipivoxil
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Subacromial Corticosteroid Injections and tDCS in Rotator Cuff Tendinopathy
Status: COMPLETED
Conditions: Rotator Cuff Tendinosis|Rotator Cuff Impingement Syndrome|Rotator Cuff Impingement|Rotator Cuff Injuries|Rotator Cuff Syndrome of Shoulder and Allied Disorders
Interventions: DEVICE: Transcranial direct current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Can Computer-based Telephone Counseling Improve Long-term Adherence to Strength Training in Elders With Knee OA?
Status: COMPLETED
Conditions: Osteoarthritis of the Knee
Interventions: BEHAVIORAL: TLC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of The Neuromuscular Control-Based Exercise Training in the Treatment of Partial-Thickness Rotator Cuff Tears
Status: COMPLETED
Conditions: Rotator Cuff Tear or Rupture, Not Specified as Traumatic|Pain, Shoulder
Interventions: OTHER: Neuromuscular Control-Based Exercise Training Group|OTHER: Conventional Exercise Training Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Open-label Study of FT-2102 With or Without Azacitidine or Cytarabine in Patients With AML or MDS With an IDH1 Mutation
Status: COMPLETED
Conditions: Acute Myeloid Leukemia|Acute Myelogenous Leukemia|Myelodysplastic Syndrome
Interventions: DRUG: FT-2102 (olutasidenib)|DRUG: Azacitidine|DRUG: Cytarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigation of Bioequivalence of Ethinylestradiol (EE) and Drospirenone (DRSP) in Two Different Tablet Formulations: Yasmin and Yasmin + Levomefolate Calcium (Metafolin) & L-5-MTHF in Two Different Tablet Formulations: Levomefolate Calcium (Metafolin) and Yasmin + Levomefolate Calcium (Metafolin)
Status: COMPLETED
Conditions: Contraception
Interventions: DRUG: EE 0.03 mg/DRSP 3 mg (Yasmin, BAY86-5131)|DRUG: EE 0.03mg/DRSP 3mg/L-5-MTHF Ca 0.451mg (EE30/DRSP/L-5-MTHF Ca)|DRUG: L-5-MTHF Ca 0.451 mg (Metafolin)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sentinel Lymph Node Identification in Patients With Breast Cancer Using SPECT/CT
Status: UNKNOWN
Conditions: Early-stage Breast Cancer
Interventions: DEVICE: lymphoscintigraphy|DEVICE: Single Photon Emission Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Impact of Repeated Anthelmintic Treatment on the Risk of Malaria in Kenyan School Children
Status: COMPLETED
Conditions: Intestinal Helminthiasis|Ascariasis|Hookworm|Malaria
Interventions: DRUG: Albendazole|DIETARY_SUPPLEMENT: Vitamin C
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Allogeneic "Gammadelta T Cells (γδ T Cells)" Cell Immunotherapy in Phase 1 Hepatocellular Carcinoma Clinical Trial
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma
Interventions: BIOLOGICAL: Ex-vivo expanded allogeneic γδT cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial of Mycobacterium w in Critically Ill COVID 19 Patients
Status: COMPLETED
Conditions: COVID-19
Interventions: DRUG: Suspension of heat killed (autoclaved) Mycobacterium w|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Elotuzumab, Lenalidomide and Dexamethasone in Treatment of Transplant-Eligible Newly Diagnosed Multiple Myeloma Patients
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: elotuzumab|DRUG: Lenalidomide|DRUG: Dexamethasone|PROCEDURE: autologous stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial That Compound Clobetasol Propionate Ointment Treats Patients With Mild to Moderate Psoriasis Vulgaris.
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: Compound Clobetasol Propionate Ointment|DRUG: Calcipotriol Betamethasone Ointment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Diagnosis Performances of DEC LTS-2 Skin Patch for Onchocerciasis in Central Africa
Status: UNKNOWN
Conditions: Onchocerciasis|Loiasis|Diagnoses Disease|Neglected Diseases
Interventions: DIAGNOSTIC_TEST: LTS-2 DEC patch|DIAGNOSTIC_TEST: Skin snips
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Proton Pump Inhibitors on CF Pulmonary Exacerbations
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: Esomeprazole|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Sleep-disordered Breathing in Patients With SCI
Status: COMPLETED
Conditions: Spinal Cord Injury|Sleep-disordered Breathing|Spinal Cord Disease|Multiple Sclerosis
Interventions: BEHAVIORAL: Best practices PAP + patient Education +ongoing Support and Training|BEHAVIORAL: Sleep Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Stop Transmission of Gambiense Human African Trypanosomiasis (STROgHAT)
Status: NOT_YET_RECRUITING
Conditions: Human African Trypanosomiasis
Interventions: DRUG: Treatment of seropositive individuals (positive serology test, but parasitology not confirmed)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dyslipidemia in Type 2 Diabetes (0767-034)
Status: TERMINATED
Conditions: Diabetes Mellitus, Type II|Dyslipidemia
Interventions: DRUG: MK0767
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Capecitabine (Xeloda) in Combination Chemotherapy Versus Surgery Alone in Participants With Gastric Cancer
Status: COMPLETED
Conditions: Gastric Cancer
Interventions: DRUG: Capecitabine|DRUG: Oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Biomechanical and Microstructural Properties of Ascending Aortic Aneurysms
Status: RECRUITING
Conditions: Thoracic Aortic Aneurysms
Interventions: OTHER: Biomechanical and microstructural analysis of ATAA|RADIATION: ECG-gated CT
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p