pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Treatment of Spontaneous Hyperventilation With Remifentanil in Traumatic Brain Injury Patients
Status: UNKNOWN
Conditions: Hyperventilation|Traumatic Brain Injury
Interventions: DRUG: Remifentanil Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of Triheptanoin in Patients With Glucose Transporter 1 Deficiency Syndrome
Status: UNKNOWN
Conditions: Glucose Transporter Type 1 Deficiency Syndrome
Interventions: DRUG: Triheptanoin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pivotal Study of VNS During Rehab After Stroke (VNS-REHAB)
Status: COMPLETED
Conditions: Cerebrovascular Stroke|Upper Extremity Paresis
Interventions: DEVICE: Paired Vagus Nerve Stimulation|OTHER: Rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immunotherapy, Hormone Therapy, and AKT Inhibitor for Premenopausal ER Positive MBC
Status: RECRUITING
Conditions: Premenopausal Breast Cancer|Metastatic Breast Cancer|ER Positive Breast Cancer
Interventions: DRUG: Goserelin|DRUG: Fulvestrant|DRUG: Capivasertib|DRUG: Durvalumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Observational Cohort Study to Investigate the Risk of Thromboembolic Events in Patients Receiving Kcentra® or Plasma to Reverse Vitamin K Antagonist (VKA) Therapy in the Setting of Acute Major Bleeding
Status: COMPLETED
Conditions: Hemorrhage
Interventions: BIOLOGICAL: Kcentra®|BIOLOGICAL: Plasma
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Prospective Comparison of the Effect on Antiadhesive Barriers During Thyroid or Parathyroid Surgery
Status: RECRUITING
Conditions: Thyroidectomy|Goiter|Thyroid Cancer
Interventions: DRUG: Oxidized regenerated cellulose(ORC)|DRUG: Hyaluronic acid(HA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Headache in Undergraduate Students and Biopsychosocial Status
Status: COMPLETED
Conditions: Headache Disorders, Primary|Prevalence|Migraine|Student|Psychosocial Problem
Interventions: OTHER: personal information form|OTHER: headache-specific questionnaires|OTHER: Questionnaires for assessing biopsychosocial status
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Women's Interventions for Sexual Health: WISH
Status: COMPLETED
Conditions: Sexual Dysfunction, Physiological|Body Image|Libido; Loss, Aversion
Interventions: OTHER: Hypnotic Relaxation Intervention (HRI)|DEVICE: Vulvovaginal Atrophy (VVA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: MEM-288 Oncolytic Virus Alone and in Combination With Nivolumab in Solid Tumors Including Non-Small Cell Lung Cancer
Status: RECRUITING
Conditions: Solid Tumor|Advanced Cancer|Metastatic Cancer|Non Small Cell Lung Cancer|Cutaneous Squamous Cell Carcinoma|Merkel Cell Carcinoma|Melanoma|Pancreatic Cancer|Triple Negative Breast Cancer|Head and Neck Cancer
Interventions: BIOLOGICAL: MEM-288 Intratumoral Injection|BIOLOGICAL: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of Zingo in Chinese Children
Status: COMPLETED
Conditions: Catheter Site Pain|Pain, Acute|Anesthesia, Local
Interventions: DRUG: Lidocaine (Zingo)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Sirolimus Prophylaxis for aGVHD in TME SCID
Status: WITHDRAWN
Conditions: Severe Combined Immunodeficiency|Transplacental Maternal Engraftment|Stem Cell Transplant
Interventions: DRUG: Sirolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Diet as a Potential Treatment for Autosomal Dominant Polycystic Kidney Disease
Status: COMPLETED
Conditions: Autosomal Dominant Polycystic Kidney Disease (ADPKD)
Interventions: BEHAVIORAL: Diet and water adjustment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Transcutaneous Acupoint Electrical Stimulation on Postoperative Spontaneous Voiding for Laparoscopic Patients
Status: COMPLETED
Conditions: Voiding Disorders
Interventions: DEVICE: TAES treatmen|DEVICE: Sham TAES treatmen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Late Effects of Ethanol Intake on the Glucose Response to Subcutaneous Glucagon in Type 1 Diabetes
Status: COMPLETED
Conditions: Hypoglycemia|Diabetes Mellitus, Type 1
Interventions: DIETARY_SUPPLEMENT: Alcohol|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Fastreset Study: Metabolic Effects of a Five-day Remotely Delivered Hypocaloric and Ketogenic Program
Status: RECRUITING
Conditions: Healthy Nutrition|Healthy Lifestyle
Interventions: OTHER: Five-day hypocaloric and ketogenic programme
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Safety and Immune Response of Candidate H1N1 Influenza Vaccines GSK2340274A and GSK234072A in Children 3 to Less Than 10 Years Old
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: GSK Biologicals' GSK2340274A (two different formulations)|BIOLOGICAL: GSK Biologicals' - GSK2340272A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Short-term Oxygen During CPET in HFpEF
Status: COMPLETED
Conditions: Heart Failure, Diastolic (HFpEF)
Interventions: PROCEDURE: Oxygen application|PROCEDURE: Sham room air
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Shensong Yangxin Capsule in the Treatment of Heart Failure Complicated With Ventricular Premature Beat
Status: UNKNOWN
Conditions: Heart Failure|Ventricular Premature Complex
Interventions: DRUG: Shensong Yangxin capsule|DRUG: placebo Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Symptom-related Screening for Early Detection of CTEPH.
Status: COMPLETED
Conditions: CTEPH|Pulmonary Embolism|Symptoms and Signs|Dyspnea
Interventions: DIAGNOSTIC_TEST: dyspnea grade ≥ II according NYHA-WHO
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy and Safety of Metamizole Versus Placebo as Antithermic Therapy in the Acute Phase of Ischemic Stroke
Status: TERMINATED
Conditions: Stroke
Interventions: DRUG: Metamizole|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Monitoring of Donor-specific Antibodies After Treatment With Immunoglobulins, Plasmapheresis and Rituximab in Lung Transplantation
Status: RECRUITING
Conditions: Lung Transplantation|Donor-specific Anti-human Leukocyte Antigen(HLA) Antibodies
Interventions: DIAGNOSTIC_TEST: blood samples
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of LY3322207 in Healthy Participants and in Participants With Hypertension (High Blood Pressure)
Status: TERMINATED
Conditions: Hypertension
Interventions: DRUG: LY3322207|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: MaxSimil and Vitamin K2: Determining Their Bioavailability
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Omega-3 + vitamin K2 (TG form of omega-3)|DIETARY_SUPPLEMENT: Omega-3 + vitamin K2 (EE form of omega-3)|DIETARY_SUPPLEMENT: Omega-3 + vitamin K2 [MaxSimil (MAG form of omega-3)]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Balloon Catheter Versus Ocytocin for Cervical Ripening on Scarred Uterus With Unfavorable Cervix
Status: COMPLETED
Conditions: Scarred Uterus
Interventions: DRUG: oxytocin|PROCEDURE: balloon catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose:
Clinical trial: PUBMIC (Prophylactic Use of Biologic Mesh in Ileal Conduit)
Status: ACTIVE_NOT_RECRUITING
Conditions: Bladder Carcinoma|Hernia
Interventions: OTHER: Acellular Cadaveric Dermal Matrix
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Efficacy of PSB and Recto-intercostal Block Combination on Postoperative Pain in Patients Undergoing Cardiac Surgery Via Sternotomy: Case Series
Status: NOT_YET_RECRUITING
Conditions: Post Operative Pain
Interventions: OTHER: Parasternal Block and Recto-İntercostal Fascial Plane Block
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Prospect Eval of Efficacy of CMV-TCIP Direct Letermovir Prophylax After Allogen Hemato Cell Transpla
Status: RECRUITING
Conditions: CMV|Allogeneic Stem Cell Transplantation
Interventions: DRUG: Letermovir|DEVICE: CMV T Cell Immunity Panel (CMV-TCIP)|DIAGNOSTIC_TEST: CMV DNA PCR
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Association Between Smell Training and Quality of Life in Patients With Impaired Sense of Smell Following COVID-19
Status: RECRUITING
Conditions: COVID-19
Interventions: OTHER: Olfactory training with essential oils|OTHER: Olfactory training with fragrance-free oils
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mesh Suture for Internal Load Bearing Closures
Status: WITHDRAWN
Conditions: Suture; Complications, Mechanical|Suture; Complications, Infection or Inflammation|Suture, Complication
Interventions: DEVICE: Duramesh Suturable Mesh
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Study of Multiple Doses of ORM-12741 (Nebula PK 2)
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: ORM-12741 MR A|DRUG: ORM-12741 MR B|DRUG: ORM-12741 IR
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Internet-Versus Group-Administered Cognitive Behavior Therapy for Panic Disorder
Status: COMPLETED
Conditions: Panic Disorder
Interventions: BEHAVIORAL: Internet-based cognitive behavior therapy (CBT).|BEHAVIORAL: Group CBT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Multicenter Phase 3 Study of Interferon-beta-1a for the Treatment of Chronic Hepatitis C in Asian Subjects
Status: COMPLETED
Conditions: Hepatitis C
Interventions: DRUG: Interferon-beta-1a|DRUG: Placebo|DRUG: Ribavirin plus Interferon-beta-1a
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The OPENS Trial: Offering Women PrEP (Aim 1)
Status: COMPLETED
Conditions: Human Immunodeficiency Virus Transmission|Sexually Transmitted Diseases
Interventions: BEHAVIORAL: HIV Prevention Decision Support Tool (DST)|BEHAVIORAL: Standard Counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Comparative Study of Capsule Endoscopy, Magnetic Resonance Imaging and Computer Tomography Scanning of the Small Bowel in Crohn's Disease
Status: COMPLETED
Conditions: Crohn's Disease
Interventions: PROCEDURE: Magnetic resonance imaging, computed tomography scanning and capsule endoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: DIAGNOSTIC
Clinical trial: Distracting Through Procedural Pain and Distress
Status: COMPLETED
Conditions: Chronic Illness|Hematologic Malignancy|Bone Marrow Transplant Infection|Oncology|Sickle Cell Disease
Interventions: OTHER: Guided Imagery|OTHER: Virtual Reality
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Long Term Effects of Oral Versus Transdermal Estrogen Replacement Therapy in Turner Syndrome
Status: RECRUITING
Conditions: Turner Syndrome|Hypogonadism; Ovarian|Hormone Replacement Therapy|Estrogen Replacement Therapy|Estrogen Deficiency
Interventions: DRUG: 17-beta estradiol|DRUG: 17-beta estradiol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of EECP on Anterior Ischemic Optic Neuropathy
Status: UNKNOWN
Conditions: Anterior Ischemic Optic Neuropathy
Interventions: DEVICE: Enhanced external counterpulsation|DRUG: Aspirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Human Umbilical Cord Blood (RegeneCyte) Infusion in Patients With Post-COVID Syndrome
Status: ACTIVE_NOT_RECRUITING
Conditions: Long COVID|Post-COVID Syndrome|Post COVID-19 Condition
Interventions: BIOLOGICAL: RegeneCyte|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: SCH-58500 in Treating Patients With Primary Ovarian, Fallopian Tube, or Peritoneal Cancer (C95084)
Status: COMPLETED
Conditions: Fallopian Tube Cancer|Metastatic Cancer|Ovarian Cancer|Primary Peritoneal Cavity Cancer
Interventions: BIOLOGICAL: recombinant adenovirus-p53 SCH-58500
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: A Bioequivalence Study Comparing Amodiaquine Tablet (Pfizer) To Amodiaquine Tablets (Arsuamoon-Guilin China) In Healthy Subjects
Status: COMPLETED
Conditions: Falciparum Malaria
Interventions: DRUG: Amodiaquine (Test)|DRUG: Amodiaquine (Comparator)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Combination of Abemaciclib and Endocrine Therapy in Hormone Receptor Positive HER2 Negative Locally Advanced or Metastatic Breast Cancer With Focus on Digital Side Effect Management
Status: RECRUITING
Conditions: Hormone Receptor-positive Metastatic Breast Cancer|HER2-negative Metastatic Breast Cancer
Interventions: DRUG: Abemaciclib + Aromatase Inhibitor|DRUG: Abemaciclib + Fulvestrant
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Study of APRF/CGF Technology in GTR
Status: UNKNOWN
Conditions: Chronic Periodontitis|Intrabony Periodontal Defect
Interventions: OTHER: APRF|OTHER: CGF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Radial Artery Assessment in Surgical Coronary Revascularisation
Status: RECRUITING
Conditions: Coronary Artery Bypass Grafting|Coronary Artery Disease
Interventions: DIAGNOSTIC_TEST: Modified Allen Test|DIAGNOSTIC_TEST: Pulse-oximetry guided Modified Allen Test|DIAGNOSTIC_TEST: Barbeau Test|DIAGNOSTIC_TEST: Ultrasound examination of the forearm arteries|DIAGNOSTIC_TEST: Measurement of oxygen saturation|OTHER: Radial Artery Quality Evaluation Survey|OTHER: Follow-up Radial Artery Harvesting Scale
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phase 3 Study to Evaluate Intravenous Trappsol(R) Cyclo(TM) in Pediatric and Adult Patients With Niemann-Pick Disease Type C1
Status: ACTIVE_NOT_RECRUITING
Conditions: Niemann-Pick Disease, Type C1
Interventions: DRUG: Hydroxypropyl-beta-cyclodextrin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial of Vitamin D and Health Advice for the Prevention of Upper Respiratory Tract Infections
Status: COMPLETED
Conditions: Upper Respiratory Tract Infections|Rhinovirus|Infections
Interventions: DIETARY_SUPPLEMENT: cholecalciferol (vitamin D3)|BEHAVIORAL: Gargling|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Backward vs Forward Gait Training With Auditory Feedback in Patients With Stroke
Status: RECRUITING
Conditions: Stroke, Ischemic
Interventions: OTHER: Backward Gait Training|OTHER: Forward Gait Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Topical Bevacizumab for Preventing Recurrent Pterygium
Status: COMPLETED
Conditions: Pterygium|Bevacizumab|VEGF|Anti-VEGF
Interventions: DRUG: bevacizumab eye drop 0.05%|DRUG: normal saline 0.9%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Capsaicin 8% Patch for Spinal Cord Injury Neuropathic Pain
Status: COMPLETED
Conditions: Spinal Cord Injuries|Neuropathic Pain
Interventions: DRUG: Capsaicin 8% Patch|DRUG: Low Dose Capsaicin 0.025% Well Patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: CC-5013 With or Without Dexamethasone in Treating Patients With Primary Systemic Amyloidosis
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: dexamethasone|DRUG: lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Bioactiveglass Air Abrasion Versus Fluoride Varnish in Management of Dentin Hypersensitivity
Status: COMPLETED
Conditions: Hypersensitivity Dentin|Tooth Hypersensitivity
Interventions: COMBINATION_PRODUCT: Sylc|COMBINATION_PRODUCT: fluoride varnish (Bifluorid 10)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Effects of Savolitinib on the Pharmacokinetics of Digoxin, Rosuvastatin, Metformin, and Furosemide in Healthy Male Subjects
Status: COMPLETED
Conditions: Healthy Male Subjects
Interventions: DRUG: Savolitinib|DRUG: Digoxin|DRUG: Metformin Hydrochloride|DRUG: Rosuvastatin|DRUG: Furosemide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Trial to Compare the Efficacy and Safety of a Single Bolus of TNK-tPA (Tenecteplase, Metalyse®) With Accelerated Infusion of Rt-PA (Alteplase, Actilyse®) in Asian Patients With Acute Myocardial Infarction
Status: COMPLETED
Conditions: Myocardial Infarction
Interventions: DRUG: TNK-tPA|DRUG: rt-PA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Two Cognitive-Behavioral Interventions on Cervical Cancer Patients
Status: ENROLLING_BY_INVITATION
Conditions: Cervical Cancer|Psychological Distress|Coping Skills
Interventions: OTHER: Psychoeducation|OTHER: Relaxation|OTHER: Cognitive Restructuring|OTHER: Solving Problems
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Adjuvant Nivolumab After Salvage Resection in Head and Neck Cancer Patients Previously Treated With Definitive Therapy
Status: ACTIVE_NOT_RECRUITING
Conditions: Head and Neck Cancer
Interventions: DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Nutrition Labeling on Fast Food Choices
Status: COMPLETED
Conditions: Healthy
Interventions: BEHAVIORAL: Menu: calories=yes, value pricing=no|BEHAVIORAL: Menu: calories=yes, value pricing = yes|BEHAVIORAL: Menu: calories=no, value pricing = no
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Temsirolimus (CCI-770, Torisel) Combined With Cetuximab in Cetuximab-Refractory Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer|Colorectal Adenocarcinoma
Interventions: DRUG: Temsirolimus|DRUG: Cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Anesthesia Maintenance Methods on 5-year Survival After Surgery
Status: UNKNOWN
Conditions: Aged|Neoplasms|Surgical Procedure, Operative|Anesthesia, Inhalation|Anesthesia, Intravenous|Survival
Interventions: DRUG: Sevoflurane|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Intraparenchymal Therapy With Irinotecan Drug Eluting Beads as Adjunct to Recurrent Surgically Resectable High Grade Glioma
Status: TERMINATED
Conditions: Glioma
Interventions: PROCEDURE: CM-BC2 Irinotecan drug-eluting bead
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Abiraterone Acetate in Combination With Docetaxel After Disease Progression to Abiraterone Acetate in Metastatic Castration Resistant Prostate Cancer.
Status: COMPLETED
Conditions: Metastatic Prostate Cancer
Interventions: DRUG: docetaxel 75 mg/m2 + prednisone 10 mg/d + abiraterone 1000 mg/d|DRUG: docetaxel 75 mg/m2 + prednisone 10 mg/d
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cognitive Behavioral Therapy for Insomnia and Depression Among Menopausal Women
Status: COMPLETED
Conditions: Depression|Insomnia|Cognitive Behavioral Therapy|Menopausal Depression
Interventions: BEHAVIORAL: Cognitive Behavioral Therapy Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Perineal Massage and Pelvic Floor Exercise in the Antenatal Period
Status: COMPLETED
Conditions: Urinary Incontinence|Fecal Incontinence|Sexual Dysfunction|Sexuality
Interventions: BEHAVIORAL: Pelvic Floor Dysfunction Prevention Training|BEHAVIORAL: Pelvic Floor Dysfunction Prevention Training and Perineal Massage|BEHAVIORAL: Pelvic Floor Dysfunction Prevention Training and Perineal Massage and Pelvic Floor Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of LRG-002 Hard Capsules (Lek d.d., Slovenia) Used in the Prophylaxis of Antibiotic-associated Diarrhea in Adults.
Status: COMPLETED
Conditions: Antibiotic-associated Diarrhea
Interventions: DRUG: LRG-002|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Allergy Immunotherapy for the Reduction of Asthma
Status: COMPLETED
Conditions: Wheezing|Asthma|Allergy
Interventions: BIOLOGICAL: Allergen extracts (subcutaneous injections)|OTHER: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Volatile Anaesthesia and Perioperative Outcomes Related to Cancer Feasibility Study
Status: COMPLETED
Conditions: Cancer, Breast|Cancer Colorectal|Cancer Prostate|Cancer, Lung|Cancer Melanoma Skin|Cancer, Other
Interventions: DRUG: Propofol|DRUG: isoflurane, sevoflurane or desflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Virtual Reality in the Rehabilitation in Patients With Lower Limb Amputation.
Status: RECRUITING
Conditions: Amputation|Lower Limb|Rehabilitation|Activities of Daily Living|Virtual Reality|Lower Extremity
Interventions: DEVICE: virtual reality rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Cervical SNAG Half Rotation Technique in Cervicogenic Headache Patients.
Status: COMPLETED
Conditions: Cervicogenic Headache
Interventions: OTHER: Cervical SNAGs along with conventional therapy|OTHER: Conventional Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Staccato Loxapine Pulmonary Safety in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Inhaled Placebo|DRUG: Inhaled Loxapine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Stress Factors Induced by Patient and Young Clinicien During Endodontic Treatment
Status: COMPLETED
Conditions: Endodontic Treatment
Interventions: PROCEDURE: Endodontic treatment|OTHER: VAS of stress|OTHER: CORAH scale|OTHER: HAD Scale|OTHER: Cardiovascular Parameters|OTHER: Cortisol Measurements|OTHER: Discomfort and Pain Experienced During Treatment|OTHER: Patient's preferences.|OTHER: student preferences.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pharmacokinetics and Pharmacodynamics of Biphasic Insulin Aspart 30 in Healthy Volunteers
Status: COMPLETED
Conditions: Diabetes|Healthy
Interventions: DRUG: biphasic insulin aspart 30|DRUG: biphasic human insulin 30
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Measurement of Circulating Cell-free DNA (cfDNA) for Diagnosis and Prognosis of Various Diseases and Evaluation of Tissue Damage
Status: COMPLETED
Conditions: Correlation of cFDNA During CPB to Laboratories SIRS Parameters and Clinical Outcomes
Interventions: DIAGNOSTIC_TEST: Blood samples
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: EXecution of Trans-Esophagus Echo Cardiogram in CardioPulmonary Resuscitation for Patients With Out-of-hospital Cardiac Arrest
Status: COMPLETED
Conditions: Out-Of-Hospital Cardiac Arrest
Interventions: DEVICE: transesophageal echocardiography examination during cardiopulmonary resuscitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pazopanib vs. Pazopanib Plus Gemcitabine
Status: ACTIVE_NOT_RECRUITING
Conditions: Leiomyosarcoma or Carcinosarcoma
Interventions: DRUG: Pazopanib plus Gemcitabine|DRUG: Pazopanib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimal Duration of Anticoagulation Therapy for Low-risk Pulmonary Embolism Patients With Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Venous Thrombosis|Neoplasms|Anticoagulants
Interventions: DRUG: Long DOAC|DRUG: Short DOAC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacogenetic-guided Choice of Post-surgery Analgesics
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Pain|Post Operative Pain
Interventions: OTHER: Pharmacogenetic testing|OTHER: Pharmacist note with genotype-guided analgesic recommendations|OTHER: Pharmacist detailed note with genotype-guided recommendations per CPIC guidelines
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Karenitecin in Pediatric Patients With Refractory or Recurrent Solid Tumors N10010)
Status: COMPLETED
Conditions: Solid Tumors
Interventions: DRUG: Kareniticin and cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SUPER-DIALYSIS-Study: Supera Stent Interventions in Juxta-anastomotic (re)Stenosis
Status: RECRUITING
Conditions: Stenosis of Arteriovenous Dialysis Fistula
Interventions: DEVICE: Supera™ Peripheral Stent System
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Improving Lactation Success in Mothers of Critically Infants
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Pumping
Interventions: BEHAVIORAL: Text message including biomarker of breast pumping adequacy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Post-marketing Surveillance to Assess the Safety of Infanrix-IPV Vaccine Among Infants and Children in Korea
Status: COMPLETED
Conditions: Acellular Pertussis|Diphtheria|Tetanus|Poliomyelitis|Diphtheria-Tetanus-acellular Pertussis Vaccines
Interventions: OTHER: Infanrix-IPV data collection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Impact of Sitagliptin as an Add on Therapy With Closed Loop Control in Adolescents With Diabetic Nephropathy
Status: COMPLETED
Conditions: Type 1 Diabetic Nephropathy
Interventions: DRUG: oral sitagliptin supplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Equol Supplementation on Arterial Stiffness and Cognition in Healthy Volunteers
Status: RECRUITING
Conditions: Arterial Stiffness|White Matter Lesions|Cognitive Decline
Interventions: DRUG: S-equol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Etanercept Versus Adalimumab in the Treatment of Patients With Ankylosing Spondylitis. A Switch Study
Status: UNKNOWN
Conditions: Ankylosing Spondylitis
Interventions: BIOLOGICAL: Adalimumab|BIOLOGICAL: Etanercept
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimal Treatment Protocol for Selective Laser Trabeculoplasty - Repeat Trial
Status: ENROLLING_BY_INVITATION
Conditions: Glaucoma, Open-Angle|Pseudoexfoliation Glaucoma|Ocular Hypertension
Interventions: PROCEDURE: SLT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Surfactant Administration Via Thin Catheter Using a Specially Adapted Video Laryngoscope
Status: UNKNOWN
Conditions: Respiratory Distress Syndrome
Interventions: DEVICE: using specially adapted VNscope|DRUG: surfactant administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Efficacy of Clevudine Plus Lamivudine for Lamivudine-resistant Chronic Hepatitis B Patients
Status: TERMINATED
Conditions: Chronic Hepatitis B
Interventions: DRUG: adefovir|DRUG: clevudine|DRUG: lamivudine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Mass Balance Recovery (Absorption, Distribution, Metabolism and Excretion) of [14C]CCX168 in Healthy Participants
Status: COMPLETED
Conditions: Anti-neutrophil Cytoplasmic Antibody-associated Vasculitis
Interventions: DRUG: [14C]CCX168
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: RTA 744 Injection in Patients With Leptomeningeal Disease
Status: TERMINATED
Conditions: Neoplastic Meningitis|Solid Tumor|Lymphoma|Leukemia|Brain Tumor
Interventions: DRUG: RTA 744
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adaptation of STEPPS Program for Addressing Emotional Dysregulation and Self-harming Behaviors in Penitentiary Centers
Status: ACTIVE_NOT_RECRUITING
Conditions: Self Harm
Interventions: BEHAVIORAL: Systems Training for Emotional Predictability & Problem Solving (STEPPS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reducing Sugar-sweetened Beverage Consumption Among Children
Status: COMPLETED
Conditions: Pediatric Obesity|Diet, Food, and Nutrition
Interventions: BEHAVIORAL: Commercially-available caffeine-free soda|BEHAVIORAL: Carbonated water|BEHAVIORAL: Regular soda
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: KYSA-3: A Study of Anti-CD19 Chimeric Antigen Receptor T-Cell (CD19 CAR T) Therapy, in Subjects With Refractory Lupus Nephritis
Status: RECRUITING
Conditions: Lupus Nephritis|Lupus Nephritis - WHO Class III|Lupus Nephritis - WHO Class IV
Interventions: BIOLOGICAL: KYV-101 anti-CD19 CAR-T cell therapy|DRUG: Standard lymphodepletion regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sapacitabine, Cyclophosphamide, Rituximab for Relapsed Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma (CLL/SLL) With Deletion (11q22-23)
Status: TERMINATED
Conditions: Leukemia
Interventions: DRUG: Cyclophosphamide|DRUG: Rituximab|DRUG: Sapacitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of DARZALEX (Daratumumab) In Indian Participants With Relapsed and Refractory Multiple Myeloma, Whose Prior Therapy Included a Proteasome Inhibitor and an Immunomodulatory Agent
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Daratumumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Chitosan, Ankaferd and Tranexamic Acid in Dental Extraction in Liver Pre-Transplant Children
Status: COMPLETED
Conditions: Liver Cirrhosis
Interventions: DRUG: tranexamic acid|DRUG: Ankaferd Blood Stopper|DRUG: Chitosan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: OPTIMIzation of Treatment SElection and Follow up in Oligometastatic Colorectal Cancer
Status: RECRUITING
Conditions: Colorectal Cancer|Metastatic Cancer
Interventions: OTHER: Standard of care|OTHER: Circulating tumor DNA guided treatment approach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Microcurrent Stimulation Reduces Post-Operative Swelling and Healing Time Following Knee Replacement Surgery
Status: UNKNOWN
Conditions: Osteoarthritis of Knee|Edema|Wounds and Injuries
Interventions: DEVICE: ODIN1|OTHER: Standard Care|DEVICE: Diagnostic Device Testing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bone Marrow Mononuclear Cell and Hyperbaric Oxygen Therapy in Diabetes Mellitus
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: BM-MNC+HOT|DRUG: BM-MNC|DEVICE: HOT|DRUG: SMT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Detection of Cav1 Calcium Channels in Inflammatory Cells of Asthmatic Children
Status: COMPLETED
Conditions: Asthma
Interventions: PROCEDURE: Induced sputum method using hypertonic serum
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of Naltrexone for Methamphetamine Addiction
Status: COMPLETED
Conditions: Methamphetamine Dependence
Interventions: DRUG: Naltrexone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study to Investigate the Efficacy and Safety of Lacosamide as an Add on Therapy in Children With Epilepsy With Partial-onset Seizures
Status: COMPLETED
Conditions: Epilepsy
Interventions: DRUG: Lacosamide|DRUG: Lacosamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endourology Disease Group Excellence (EDGE) Consortium: Antibiotics (Abx) for Percutaneous Nephrolithotomy (PCNL) Part 2
Status: RECRUITING
Conditions: Nephrolithiasis|Urinary Tract Infection (UTI)|Sepsis
Interventions: DRUG: Nitrofurantoin 100 MG, 7d|DRUG: Gentamicin, 5mg/kg|DRUG: Ampicillin 2g|DRUG: Nitrofurantoin 100 mg, 48 hrs|DRUG: Gentamicin, 80 mg, 7d|DRUG: Gentamicin, 80 mg, 48hr
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Prevention of Ulnar Collateral Ligament (UCL) Injuries in Minor League Pitchers
Status: UNKNOWN
Conditions: Elbow Injuries|Sprain Ulnar Collateral Ligament|Upper Extremity Injuries|Strain of Ulnar Collateral Ligament|Complete Tear Ulnar Collateral Ligament
Interventions: OTHER: Strengthening program|OTHER: Exercise program
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Outcomes for Medicare Asthma Patients Taking Fluticasone Propionate/Salmeterol Xinafoate Combination Versus Inhaled Corticosteroids or Other Combination Therapy
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: fluticasone propionate/salmeterol xinafoate combination|DRUG: inhaled corticosteroids
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Impact of Oligosaccharides and Bifidobacteria on the Intestinal Microflora of Premature Infants
Status: COMPLETED
Conditions: Fecal Microflora in the Formula Fed Premature Infant
Interventions: DIETARY_SUPPLEMENT: ProlactPlus|DIETARY_SUPPLEMENT: GOS galacto-oligosaccharides|DIETARY_SUPPLEMENT: Bifidobacterium infantis|DIETARY_SUPPLEMENT: Bifidobacterium animalis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Assess Extent of Agreement Between Online 24-hr Dietary Recall and Interviewer-administered 24-hr Dietary Recall on the Same Day for 2 Non-consecutive 2 Days 1 wk Apart to Adults and School Age Children
Status: COMPLETED
Conditions: Dietary Habits
Interventions: OTHER: Dietary assessment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study to Evaluate the Safety, Tolerability, and Efficacy of ASC41 in Adults With NASH
Status: WITHDRAWN
Conditions: Nonalcoholic Steatohepatitis (NASH)
Interventions: DRUG: ASC41 2 mg|DRUG: ASC41 4 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immunosuppression During Penetrating Keratoplasty, Using a Subconjunctival Implant Releasing Dexamethasone : Tolerance and Safety Pilot Study
Status: COMPLETED
Conditions: Keratoconus|Fuchs' Endothelial Dystrophy|Congenital Hereditary Stromal Dystrophy of the Cornea
Interventions: DRUG: Dexamethasone implant OZURDEX
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effects of Transcranial Direct Current Stimulation (tDCS) for the Treatment of Refractory Epilepsy
Status: UNKNOWN
Conditions: Epilepsy Intractable
Interventions: PROCEDURE: Cathodal Transcranial Direct Current Stimulation|PROCEDURE: Sham Transcranial direct current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mechanisms of Adverse Effects of Long-Acting Beta-Agonists in Asthma
Status: RECRUITING
Conditions: Asthma
Interventions: DRUG: Salmeterol Xinafoate|DRUG: Salmeterol Fluticasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Yoga for Painful Chemotherapy-Induced Peripheral Neuropathy: A Pilot, Randomized-Controlled Study
Status: COMPLETED
Conditions: Chemotherapy-induced Peripheral Neuropathy|Yoga|Chronic Pain|Neuropathic Pain
Interventions: BEHAVIORAL: Yoga
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluating Efficacy of Tivozanib (AV-951) in Biliary Tract Cancers
Status: RECRUITING
Conditions: Cholangiocarcinoma|Bile Duct Neoplasm|Biliary Tract Malignancy
Interventions: DRUG: Tivozanib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: COMPASS Across Settings (CAST) for Improving Transition Outcomes for Students With ASD
Status: RECRUITING
Conditions: Autism|Autism Spectrum Disorder|Autistic Disorder
Interventions: BEHAVIORAL: COMPASS Across Settings (CAST)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acute Effect of Positive Expiratory Pressure Versus Breath Stacking Technique After Cardiac Surgery
Status: COMPLETED
Conditions: Complication, Postoperative|Cardiac Complication
Interventions: OTHER: Breath Stacking|OTHER: Expiratory Positive Airway Pressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Immunochemotherapy for Adenocarcinoma of the Esophagogastric Junction
Status: NOT_YET_RECRUITING
Conditions: Esophageal Cancer
Interventions: DRUG: neoadjuvant anti-PD-1 with DOC chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Oxytocin on the Gastric Emptying
Status: COMPLETED
Conditions: Postprocedural Delayed Gastric Emptying
Interventions: DRUG: oxytocin|DRUG: oxytocin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Analytical and Functional Evaluation of Recovery Following Acute Rupture of the Achilles Tendon and Surgical Repair in Young Patients
Status: COMPLETED
Conditions: Acute Unilateral Rupture of the Achilles Tendon
Interventions: OTHER: Questionnaire|OTHER: Static stabilometry|OTHER: Isokinetic test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Studies on Tumors of the Thyroid
Status: RECRUITING
Conditions: Hurthle Cell Thyroid Cancer|Tall Cell Variant Thyroid Cancer|Follicular Thyroid Cancer|Thyroid Cancer|Papillary Thyroid Cancer
Interventions: DRUG: 68-Gallium Dotatate
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: An All Comers Registry For Normothermic Ex Vivo Lung Perfusion (EVLP) as Assessment of Donor Lungs for Transplant
Status: RECRUITING
Conditions: Lung Transplant
Interventions: DEVICE: XVIVO Perfusion System (XPS™) with STEEN Solution™
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical Trial to Examine the Pain Relief of PH-797804 Alone Or With Naproxen in Subjects With Osteoarthritis of the Knee
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DRUG: PH-797804|DRUG: Placebo|DRUG: Placebo|DRUG: PH-797804|DRUG: Naproxen|DRUG: Naproxen + PH-797804|DRUG: Naproxen + PH-797804|DRUG: Naproxen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Acute Effect of Static Stretching and Pilates Stretching on the Muscle Strength
Status: COMPLETED
Conditions: Muscle Strength|Muscle Strength Dynamometer
Interventions: OTHER: Static stretching|OTHER: Pilates stretching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Venous Stent for the Iliofemoral Vein Investigational Clinical Trial Using the DUO Venous Stent System
Status: ACTIVE_NOT_RECRUITING
Conditions: May-Thurner Syndrome|Deep Vein Thrombosis|Chronic Venous Insufficiency
Interventions: DEVICE: Duo Venous Stent System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT