pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Impact of Therapy Using Colesevelam Treatment Reducing Bile Acids in Patients With Fontan Circulation.
Status: NOT_YET_RECRUITING
Conditions: Fontan Circulation
Interventions: DRUG: Colesevelam|OTHER: Control Arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Testing Pfs25-EPA/Alhydrogel as a Potential Malaria Transmission Blocking Vaccine
Status: COMPLETED
Conditions: Malaria
Interventions: BIOLOGICAL: Pfs25-EPA/Alhydrogel|BIOLOGICAL: Euvax B|BIOLOGICAL: Menactra
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Study of the Experience of Patients With Osteoporosis Using the Forteo B Pen to Self Administer Once Daily Teriparatide Therapy
Status: COMPLETED
Conditions: Osteoporosis
Interventions: DRUG: teriparatide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing the Effect of Sitagliptin/Metformin and Metformin in PCOS Patients
Status: UNKNOWN
Conditions: Polycystic Ovary Syndrome|Infertility|ART
Interventions: DRUG: placebo|DRUG: metformin|DRUG: Sitagliptin|DRUG: Sitagliptin/metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Can the Thoracic Replace the Conventional Radiography for the Diagnosis of Acute Pneumonia in Children?
Status: WITHDRAWN
Conditions: Pneumonia
Interventions: OTHER: Thoracic ultrasound|OTHER: CXR
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Study to Assess the Efficacy, Immunogenicity and Safety of Liquid Human Rotavirus Vaccine, in Healthy Chinese Infants
Status: COMPLETED
Conditions: Infections, Rotavirus
Interventions: BIOLOGICAL: GSK Biologicals' liquid human rotavirus vaccine 444563|BIOLOGICAL: Placebo|BIOLOGICAL: Infanrix™|BIOLOGICAL: Institute of Medical Biology Chinese Academy of Medical Sciences' Oral poliovirus vaccine (OPV)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Oral Direct Factor Xa Inhibitor BAY59-7939 in Patients With Acute Symptomatic Proximal Deep Vein Thrombosis(ODIXa-DVT)
Status: COMPLETED
Conditions: Venous Thrombosis|Deep Vein Thrombosis
Interventions: DRUG: Xarelto (Rivaroxaban, BAY59-7939)|DRUG: Xarelto (Rivaroxaban, BAY59-7939)|DRUG: Xarelto (Rivaroxaban, BAY59-7939)|DRUG: Xarelto (Rivaroxaban, BAY59-7939)|DRUG: Enoxaparin/Vitamin K-Antagonist
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Trigger Point Dry Needling in Individuals With Patello Femoral Pain Syndrome : A Randomized Controlled Trial
Status: COMPLETED
Conditions: Patellofemoral Pain Syndrome
Interventions: OTHER: Dry Needling|OTHER: Sham Dry Needing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing Validity of Non-Invasive Hemoglobin Monitoring to Laboratory Results in Critically Ill Children
Status: COMPLETED
Conditions: Hemoglobin Results
Interventions: OTHER: Masimo Pronto Rad 7 Non-Invasive hemoglobin monitor|OTHER: Standard Laboratory Blood Draw and Hemoglobin Analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: TRANSCRANIAL DIRECT CURRENT STIMULATION (t-DCS) AS ADD-ON TO NEUROREHABILITATION OF PISA SYNDROME IN PARKINSON DISEASE
Status: COMPLETED
Conditions: Parkinson Disease|Pisa Syndrome
Interventions: OTHER: t-DCS group|OTHER: Sham group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Stratifying Crohn's Using Biomarker Assessment
Status: UNKNOWN
Conditions: Crohn Disease in Remission
Interventions: OTHER: Faecal calprotectin (FC)|OTHER: quantitative Faecal Immunochemical Testing (qFIT)|OTHER: Serum and faecal zinc
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Acute Hemostasis Following the Use of the AQUABEAM® System for the Treatment of Benign Prostatic Hyperplasia
Status: COMPLETED
Conditions: Benign Prostatic Hyperplasia
Interventions: DEVICE: AquaBeam System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tranexamic Acid Dosing in Adult Spinal Deformity Surgery
Status: COMPLETED
Conditions: Adult Spinal Deformity
Interventions: DRUG: Tranexamic Acid (Cyklokapron)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of Three Drug Combinations in HIV-Infected Patients Who Have Taken Zidovudine for More Than 12 Weeks
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Stavudine|DRUG: Zidovudine|DRUG: Didanosine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Lenalidomide/Bortezomib/Dexamethasone for Multiple Myeloma (MM)
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Lenalidomide|DRUG: Bortezomib|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Different Onset Times of Treatment With Pulsed Dye Laser on Improvement of Surgical Scars
Status: TERMINATED
Conditions: Scar
Interventions: PROCEDURE: pulsed dye laser therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Phase 2B Study on Safety and Therapeutic Efficacy of DAS181 in Adult Subjects With Naturally Acquired Influenza
Status: COMPLETED
Conditions: Influenza
Interventions: DRUG: DAS181-F02 formulation|DRUG: DAS181-F04 formulation|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Sub-dissociative Ketamine for the Management of Acute Pediatric Pain
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Ketamine|DRUG: Morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dopamine D2 Receptors(D2R) Imaging in Nonfunctioning Pituitary Adenoma(NFPA)
Status: UNKNOWN
Conditions: Pituitary Adenoma
Interventions: DRUG: Drug treatment|OTHER: Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose-response Study of the Safety and Efficacy of Beraprost Sodium Modified Release (BPS-MR) in Patients With Pulmonary Arterial Hypertension (PAH)
Status: COMPLETED
Conditions: Pulmonary Arterial Hypertension
Interventions: DRUG: Beraprost Sodium Modified Release
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: To Evaluate Safety, Tolerability, Plasma Drug Levels And Other Biological Effects In Healthy Volunteers
Status: TERMINATED
Conditions: Healthy
Interventions: DRUG: PF-03382792 Cohort 1|DRUG: PF-03382792 Cohort 2|DRUG: PF-03382792|DRUG: Food Effect cohort|DRUG: CSF cohort
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Living WELL: A Web-Based Program for Ovarian Cancer Survivors
Status: RECRUITING
Conditions: Ovarian Cancer
Interventions: BEHAVIORAL: Technology-based Mindful Living program|BEHAVIORAL: Technology-based Healthy Lifestyles program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of CST-2032 and CST-107 in Subjects With Mild Cognitive Impairment or Mild Dementia Due to Parkinson's or Alzheimer's Disease
Status: COMPLETED
Conditions: Mild Cognitive Impairment|Dementia
Interventions: DRUG: CST-2032, matching placebo for CST-2032, CST-107, matching placebo for CST-107
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Secukinumab With 2 mL Pre-filled Syringes
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: Placebo|DRUG: Secukinumab 2 mL form|DRUG: Secukinumab 1 mL form
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating Safety, Pharmacodynamics and Pharmacokinetics of HSK3486 and Etomidate for Induction of Anesthesia in Healthy Male Subjects
Status: COMPLETED
Conditions: General Anesthetic|Sedation
Interventions: DRUG: HSK3486+ etomidate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Active Release Technique and Post Isometric Relaxation Technique on Pain and Functional Disability in Patient With Mechanical Neck Pain
Status: UNKNOWN
Conditions: Neck Pain
Interventions: OTHER: Active release technique|OTHER: Post isometric relaxation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Improving Social Relationships for Adolescents With Central Disorders of Hypersomnolence
Status: RECRUITING
Conditions: Narcolepsy Type 1|Narcolepsy Type 2|Idiopathic Hypersomnia
Interventions: BEHAVIORAL: Web-based psychoeducational resource
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study Evaluating Levonorgestrel and Ethinyl Estradiol in Oral Contraception
Status: COMPLETED
Conditions: Oral Contraceptive
Interventions: DRUG: Levonorgestrel 90 mg and Ethinyl Estradiol 20 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: ECT
Clinical trial: Safety and Efficacy of MK0594 to Treat Overactive Bladder (0594-003)
Status: COMPLETED
Conditions: Urinary Incontinence|Overactive Bladder
Interventions: DRUG: MK0594
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Metformin in Patients With Fragile X
Status: UNKNOWN
Conditions: Fragile X Syndrome
Interventions: DRUG: Metformin|DRUG: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Local Antibiotic Injection Via a Catheter for Treating Acute Periprosthetic Infections After Knee DAIR Surgery
Status: NOT_YET_RECRUITING
Conditions: Local Antibiotic Injection Catheter Acute Periprosthetic Infections Knee DAIR Randomized Controlled Trial
Interventions: DEVICE: Drug infusion into joint through catheter.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fisher Wallace Neurostimulation & Depression Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Major Depressive Disorder
Interventions: DEVICE: Fisher Wallace Cranial Electrotherapy Stimulator Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lung Ultrasound-guided Fluid Resuscitation in Neonatal Septic Shock
Status: COMPLETED
Conditions: Septic Shock
Interventions: DIAGNOSTIC_TEST: lung ultrasound-guided fluid resuscitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Observational Study to Evaluate the Efficacy and Safety of Bortezomib, Melphalan, Prednisone (VMP) in Participants With Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Bortezomib|DRUG: Melphalan|DRUG: Prednisone
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Amino Acid Kinetics of GMP-AA in Healthy Human Volunteers
Status: ACTIVE_NOT_RECRUITING
Conditions: Phenylketonurias
Interventions: DIETARY_SUPPLEMENT: Casein|DIETARY_SUPPLEMENT: L-amino acids|DIETARY_SUPPLEMENT: CGMP-AA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Pilot Study Using Placenta Derived Decidual Stromal Cells for Hemorrhagic Cystitis
Status: COMPLETED
Conditions: Hemorrhagic Cystitis
Interventions: BIOLOGICAL: Decidual Stromal Cell therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial on the Ideal Duration of Oral Antibiotics in Children With Pneumonia
Status: COMPLETED
Conditions: Pneumonia
Interventions: DRUG: Amoxicillin-Potassium Clavulanate Combination|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Pharmacokinetic And QT Study Of CP-751,871 In Healthy Subjects
Status: TERMINATED
Conditions: Healthy Volunteers
Interventions: BIOLOGICAL: CP-751,871|BIOLOGICAL: CP-751,871|BIOLOGICAL: CP-751,871, moxifloxacin, saline
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Splint Versus Non-splint Implant Impressions
Status: WITHDRAWN
Conditions: Dental Implants|Dental Impression Materials|Dental Impression Techniques
Interventions: PROCEDURE: Snow white plaster 2|PROCEDURE: Primopattern LC gel + PVS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Postoperative Gastric Point of Care Ultrasound (G-POCUS) in Abdominal Surgery
Status: RECRUITING
Conditions: Ileus Postoperative|Postoperative Nausea and Vomiting
Interventions: DIAGNOSTIC_TEST: gastric point of care ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Tocilizumab for KSHV-Associated Multicentric Castleman Disease
Status: COMPLETED
Conditions: Castleman Disease|Multicentric Castleman Disease|Giant Lymph Node Hyperplasia
Interventions: DRUG: Zidovudine|DRUG: Tocilizumab|DRUG: Valganciclovir (VGC)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Coaches Activating Reaching and Engaging Patients
Status: COMPLETED
Conditions: Cancer|End-of-Life
Interventions: BEHAVIORAL: Lay Navigator Intervention|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Specialized Amino Acid Mixture on Body Composition and Skin State in Overweight and Obese Class I Postmenopausal Women
Status: COMPLETED
Conditions: Amino Acid|Body Weight Changes|Skin Manifestations|Obesity|Postmenopausal Disorder
Interventions: DIETARY_SUPPLEMENT: L-glutamine, L-arginine and calcium beta-hydroxy-beta-methylbutyrate|COMBINATION_PRODUCT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Palonosetron in Moderately and Highly Emetogenic Chemotherapy Induced Nausea and Vomiting (Study P04935)(COMPLETED)
Status: COMPLETED
Conditions: Neoplasms|Nausea|Vomiting
Interventions: DRUG: Palonosetron
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Myopia Control With Orthokeratology Contact Lenses in Spain
Status: COMPLETED
Conditions: Myopia, Progressive|Children, Only|Contact Lens Complication|Perception, Self|Axial Myopia
Interventions: DEVICE: Menicon Z Night|DEVICE: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of JNJ-90014496 in Participants With Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma
Status: RECRUITING
Conditions: Relapsed or Refractory B Cell Non-Hodgkin Lymphoma
Interventions: BIOLOGICAL: JNJ-90014496
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study on How Fiasp® Can Influence Blood Sugar Levels of type1 Diabetic Patients in Their Daily Lives, With the Help of the Freestyle Libre® Device
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 1 Diabetes
Interventions: DRUG: Fast-acting insulin aspart
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: High-intensity Laser Therapy for Sacroiliac Joint Pain
Status: ACTIVE_NOT_RECRUITING
Conditions: Sacroiliac Joint Pain
Interventions: DEVICE: Laser Therapy|OTHER: Traditional exercises|OTHER: Placebo laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effects of VMX-C001 on the Anticoagulant Effect of Different Forms of Heparin
Status: RECRUITING
Conditions: Coagulation Disorder
Interventions: DRUG: VMX-C001|DRUG: Rivaroxaban|DRUG: UFH|DRUG: Enoxaparin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Deep Brain Stimulation in Treatment Resistant Major Depression
Status: COMPLETED
Conditions: Major Depression
Interventions: DEVICE: DBS|DEVICE: No Stimulation (Sham)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Kinesiotaping in Treatment of Pes Anserinus Tendino-bursitis
Status: COMPLETED
Conditions: Pes Anserinus Tendinobursitis
Interventions: DEVICE: Kinesiotaping|PROCEDURE: NSAIDs/Physical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility of the PERformance Guided Fracture Rehablitation Method-protocol
Status: COMPLETED
Conditions: Fracture of Proximal End of Humerus|Fracture of Distal End of Radius|Upper Extremity Fracture|Upper Limb Fracture
Interventions: OTHER: PERformance guided Fracture Rehablitation Method (PERFoRM) protocol.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Gluten Free Diet in Ulcerative Colitis
Status: NOT_YET_RECRUITING
Conditions: Inflammatory Bowel Diseases|Ulcerative Colitis
Interventions: DIETARY_SUPPLEMENT: High gluten diet|DIETARY_SUPPLEMENT: Gluten free diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluating the Efficacy of Dry Eye (DE) Disease Treatment Using Novel Tear Film Imager (TFI)
Status: COMPLETED
Conditions: Dry Eye Disease
Interventions: DEVICE: Tear Film Imager
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Randomized Controlled Trials on Clinical Outcomes of Totally Laparoscopic Versus Laparoscopy Assisted Total Gastrectomy for Gastric Cancer
Status: ENROLLING_BY_INVITATION
Conditions: Stomach Neoplasms
Interventions: PROCEDURE: Totally Laparoscopic Total Gastrectomy|PROCEDURE: Laparoscopy Assisted Total Gastrectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Project HERO: Health Empowerment & Recovery Outcomes
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Cancer|Bladder Cancer|Kidney Cancer|Colon Cancer|Rectum Cancer|Thyroid Cancer|Lung Cancer|Small Intestine Cancer|Soft Tissue Cancer
Interventions: BEHAVIORAL: Body Mind Training (BMT)|BEHAVIORAL: Body Training (BT):|BEHAVIORAL: Usual Care (UC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Assessing the Efficacy of IV Ibuprofen for Treatment of Pain in Orthopedic Trauma Patients
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: IV Ibuprofen|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: High-definition Transcranial Direct Current Stimulation (HD-tDCS) in Late-life Depression (LLD)
Status: UNKNOWN
Conditions: Depression in Old Age
Interventions: DEVICE: High-definition Transcranial Direct Current Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Vascular Endothelial Dysfunction in Sleep Apnea
Status: RECRUITING
Conditions: Obstructive Sleep Apnea of Adult
Interventions: DRUG: Atorvastatin 10mg|DRUG: Placebo|OTHER: Continuous Positive Airway Pressure Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of 2 Antifungal Treatment (Empirical Versus Pre-Empirical) Strategies in Prolonged Neutropenia
Status: TERMINATED
Conditions: Malignant Hemopathy|Duration of Neutropenia Following Chemotherapy > 10 Days
Interventions: DRUG: Amphotericin B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CSD200907: A Study to Assess Elements of Abuse Liability for a Heated Tobacco Product With Four Non-Combusted Cigarette Variants
Status: COMPLETED
Conditions: Smoking|Smoking Behaviors|Tobacco Use|Tobacco Smoking
Interventions: OTHER: Product A1|OTHER: Product B|OTHER: Product C|OTHER: Product D|OTHER: Product A2|OTHER: Product E|OTHER: Product F|OTHER: Product G|OTHER: Product H|OTHER: Product N
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effect of Dexamethasone as an Adjuvant to Bupivacaine in Bilateral Erector Spinae Block on Postoperative Pain and Diaphragmatic Function After Pediatric Cardiac Surgeries : A Randomized Controlled Clinical Trial
Status: NOT_YET_RECRUITING
Conditions: Pediatric Cardiac Surgery
Interventions: PROCEDURE: bilateral erector spinae plane block in pediatric cardiac surgeries
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Tacrolimus Monotherapy for Idiopathic Membranous Nephropathy (IMN)
Status: UNKNOWN
Conditions: Idiopathic Membranous Nephropathy
Interventions: DRUG: Tacrolimus|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety, Tolerability, and Pharmacokinetics Study of a Single Intravenous Injection of Recombinant Coagulation Factor VIII Fc - Von Willebrand Factor - XTEN Fusion Protein (rFVIIIFc-VWF-XTEN) (BIVV001) in Previously Treated Adults With Severe Hemophilia A (EXTEN-A)
Status: COMPLETED
Conditions: Hemophilia A
Interventions: BIOLOGICAL: Advate (Low Dose)|BIOLOGICAL: Advate (High Dose)|BIOLOGICAL: BIVV001 (Low Dose)|BIOLOGICAL: BIVV001 (High Dose)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Efficacy and Safety of MedifoamⓇ and BetafoamⓇ in Pressure Ulcer
Status: TERMINATED
Conditions: Pressure Ulcer
Interventions: DEVICE: Foam Dressing|DEVICE: Foam Dressing with Povidone Iodine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of Nivolumab Combined With FOLFOX and Regorafenib in People Who Have HER2-Negative Esophagogastric Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Esophagogastric Cancer|HER2-Negative
Interventions: DRUG: regorafenib|DRUG: nivolumab|DRUG: FOLFOX chemotherapy with oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mobile Message Intervention for Stroke Caregivers' Psychological Support
Status: UNKNOWN
Conditions: Stroke|Caregiver Burnout|Mobile Phone Use|Depressive Symptoms|Psychological Distress
Interventions: OTHER: Ecological Momentary Intervention (EMI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Study of a Novel Antipsychotic ITI-007 in Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: ITI-007|DRUG: Placebo|DRUG: Risperidone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cannabidiol Oral Solution as an Adjunctive Therapy for Treatment of Participants With Inadequately Controlled Dravet Syndrome
Status: WITHDRAWN
Conditions: Dravet Syndrome
Interventions: DRUG: Cannabidiol Oral Solution|DRUG: Placebo Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Ivabradine on Heart Rate & Effort Tolerance in Mitral Stenosis in Sinus Rhythm
Status: COMPLETED
Conditions: Mitral Stenosis
Interventions: DRUG: Ivabradine|DRUG: Atenolol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Usefulness of Sterile Adhesive Dressing at the Exit-site of Peritoneal Dialysis Catheter
Status: COMPLETED
Conditions: Peritoneal Dialysis
Interventions: OTHER: No dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Primary Thromboprophylaxis in Patients With Malignancy and Central Venous Catheters
Status: RECRUITING
Conditions: Venous Thromboembolism|Cancer
Interventions: DRUG: Rivaroxaban 10 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Clinical Outcome After Total Knee Arthroplasty Using CR or PS Inlay
Status: ACTIVE_NOT_RECRUITING
Conditions: Knee Osteoarthritis
Interventions: DEVICE: PS TKA|DEVICE: CR TKA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of SNK01 in Participants With Moderate Alzheimer's Disease
Status: RECRUITING
Conditions: Moderate Alzheimer Disease
Interventions: BIOLOGICAL: SNK01|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Caldonirimab Plus Nimotuzumab for Recurrent or Metastatic Cervical Cancer
Status: RECRUITING
Conditions: Cervical Cancer
Interventions: DRUG: Caldonirimab and Nimotuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Tocovid Suprabio 200mg in Non-alcoholic Fatty Liver (NAFL)
Status: COMPLETED
Conditions: Hepatic Steatosis|NAFLD
Interventions: DRUG: Tocotrienols / Vitamin E|DRUG: Placebo control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Low-dose IL-2 ( Interleukin-2) Treatment in Macrophage Activation Syndrome（MAS）
Status: UNKNOWN
Conditions: Macrophage Activation Syndrome
Interventions: DRUG: Interleukin-2
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non-invasive Neurally Adjusted Ventilator Assist or Continuous Positive Airway Pressure in Preterm Infants
Status: COMPLETED
Conditions: Premature Birth|Respiratory Distress Syndrome, Newborn
Interventions: DEVICE: CPAP|DEVICE: NIV NAVA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Oprozomib, Melphalan, and Prednisone in Transplant Ineligible Patients With Newly Diagnosed Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Oprozomib|DRUG: Melphalan|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Serial Night Time Position Splint on Systemic Sclerosis
Status: UNKNOWN
Conditions: Diffuse Systemic Sclerosis
Interventions: DEVICE: Serial night time position splint|DRUG: Drug treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Optimal Catheter Placement During Sonohysterography: Comparison of Cervical to Uterine Placement
Status: COMPLETED
Conditions: Catheter Placement and Perceived Pain
Interventions: PROCEDURE: cervical vs. uterine placement of balloon catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Spinal Cord Stimulation and Physiotherapy for Treatment of Neuropathic Pain
Status: ENROLLING_BY_INVITATION
Conditions: Neuropathic Pain
Interventions: DEVICE: Spinal Cord Stimulation (SCS)|OTHER: Physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Influence of Surface Characteristics of Gait Training on Gait Kinematics and Walking Capacity in Children With Diplegic CP
Status: UNKNOWN
Conditions: Diplegic Cerebral Palsy
Interventions: OTHER: different walking surfaces|OTHER: traditional gait training over hard surface only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Biomarkers in Bone Marrow and Blood Samples From Older Patients With Acute Myeloid Leukemia Treated With Cytarabine-Based Therapy
Status: COMPLETED
Conditions: Leukemia
Interventions: GENETIC: proteomic profiling|OTHER: flow cytometry|OTHER: laboratory biomarker analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Hydrochlorothiazide (+) Losartan Potassium vs. Amlodipine Comparative Study (0954A-314)
Status: COMPLETED
Conditions: Essential Hypertension
Interventions: DRUG: MK0954A; hydrochlorothiazide (+) losartan potassium / Duration of Treatment: 12 weeks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Efficacy and Safety of AX-8 in Chronic Cough
Status: RECRUITING
Conditions: Chronic Cough
Interventions: DRUG: AX-8, Part 1 of the study|DRUG: Placebo, Part 1 of the study|DRUG: AX-8, Part 2 of the study|DRUG: Placebo, Part 2 of the study
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the New Laser PHOTOLASE PLV-585nm for the Treatment of Rosacea
Status: TERMINATED
Conditions: Erythematotelangiectatic Rosacea
Interventions: DEVICE: Excel V 532nm (KTP) green Laser|DEVICE: PHOTOLASE PLV 585 nm yellow laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Multicenter Randomized Trial Comparing IM Nails and Plate Fixation in Distal Femur Fractures
Status: COMPLETED
Conditions: Femoral Fractures
Interventions: DEVICE: reamed, interlocking intramedullary nail|DEVICE: locking periarticular plate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: tDCS & Auditory Hallucinations in Schizophrenia
Status: TERMINATED
Conditions: Schizophrenia
Interventions: DEVICE: Active tDCS|DEVICE: control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tolerability Study of the Application of a 3M Microstructure Transdermal System
Status: COMPLETED
Conditions: Healthy
Interventions: DEVICE: Transdermal Microchannel Skin System|DEVICE: Sham device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Peripheral Nerve Blocks in Elderly Patients With Hip Fracture
Status: UNKNOWN
Conditions: Hip Fracture
Interventions: PROCEDURE: Femoral nerve and the lateral cutaneous nerve block|PROCEDURE: Lumbar plexus and sacral plexus nerve block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ofatumumab With Fludarabine and Cyclophosphamide in B-CLL Patients
Status: COMPLETED
Conditions: Leukaemia, Lymphocytic, Chronic
Interventions: DRUG: Ofatumumab 500mg|DRUG: Ofatumumab 1000mg|DRUG: Fludarabine|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Arrest of Proximal Caries Using Orthodontic Bands and Glass Ionomer Cement
Status: UNKNOWN
Conditions: Dental Caries Class II|Dental Caries in Children|Dental Caries on Smooth Surface Limited to Enamel
Interventions: DEVICE: Orthodontic Band affixed with Glass Ionomer Cement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Succinylated Human Serum Albumin (Suc-HSA) for HIV-1 Infection
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: succinylated human serum albumin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: DDI Study With Multiple-dose LX4211 and Single Dose Rosuvastatin
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Treatment A (rosuvastatin)|DRUG: Treatment B (LX4211)|DRUG: Treatment C (rosuvastatin + 400 mg LX4211 administered concomitantly)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Digital Smoking Cessation Intervention for Helping American Indians and Alaska Natives Quit Smoking
Status: NOT_YET_RECRUITING
Conditions: Cigarette Smoking-Related Carcinoma
Interventions: PROCEDURE: Biospecimen Collection|BEHAVIORAL: Smoking Cessation Intervention|BEHAVIORAL: Smoking Cessation Intervention|OTHER: Survey Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Providing Postnatal Breastfeeding Support Through the Canada Prenatal Nutrition Program
Status: TERMINATED
Conditions: Breastfeeding|Breastfeeding, Exclusive|Infant Nutrition|Complementary Feeding
Interventions: BEHAVIORAL: Postnatal Lactation Support
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Trial of an Internet-based Platform for Managing Chronic Diseases at a Distance
Status: COMPLETED
Conditions: Ischemic Heart Disease|Heart Failure|Chronic Kidney Disease|Diabetes|Chronic Obstructive Pulmonary Disease
Interventions: BEHAVIORAL: iCDM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: DESOLO - SiT Peri-Launch: A Comparison of Symbicort Single Inhaler Therapy and Conventional Best Practice for the Treatment of Persistent Asthma in Adults
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Symbicort, used twice daily (b.i.d) and as needed (prn)|DRUG: Budesonide Turbuhaler 200 µg|DRUG: Fluticasone Discus 250 µg|DRUG: Formoterol Turbuhaler 4.5 µg|DRUG: Terbutaline Turbuhaler 0.5 mg|DRUG: Salbutamol pressurized metered dose inhaler (pMDI) 100 µg|DRUG: Salmeterol Discus 50 µg|DRUG: Budesonide/Formoterol Turbuhaler 160/4.5 µg|DRUG: Fluticasone/Salmeterol Discus 250/50 µg|DRUG: Fluticasone/Salmeterol Discus 500/50 µg|DRUG: Theophylline 200 mg|DRUG: Theophylline 300 mg|DRUG: Singulair 10 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Research Study Looking at Different Oral Formulations and the Effect of Food Intake on How the Medicine NNC0487-0111 Behaves in the Body of Participants Living With Overweight or Obesity
Status: RECRUITING
Conditions: Obesity|Overweight
Interventions: DRUG: NNC0487-0111 (formulation D)|DRUG: NNC0487-0111 (formulation C)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Dose Titration Study of Fentanyl Buccal Soluble Film for Breakthrough Cancer Pain in Taiwan
Status: COMPLETED
Conditions: Breakthrough Cancer Pain
Interventions: DRUG: Fentanyl buccal soluble film (FBSF)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effect of Hepatic Impairment on the Pharmacokinetics of Erdafitinib
Status: TERMINATED
Conditions: Hepatic Impairment
Interventions: DRUG: Erdafitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Efficacy of Mother's Time in Ethiopia
Status: COMPLETED
Conditions: Depression, Postpartum|Anxiety, Postpartum|Contraceptive Usage
Interventions: BEHAVIORAL: Mother's Time
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Combined Administration of Nebulized Amikacin in Patients With Acute Exacerbation of Non-Cystic Fibrosis Bronchiectasis
Status: COMPLETED
Conditions: Non-Cystic Fibrosis Bronchiectasis
Interventions: DRUG: Amikacin|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Beclomethasone Aqueous Spray and Aerosol Delivery Systems in Nasal Polyps
Status: COMPLETED
Conditions: Nasal Polyps
Interventions: DRUG: Intranasal Beclomethasone aerosol|DRUG: Intranasal Beclomethasone spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: ElectrocardioGraphic Imaging During Left bUndle Branch Implant to valiDate Ecg Criteria
Status: RECRUITING
Conditions: Cardiac Resynchronization Therapy
Interventions: DEVICE: ECGI system during LBBP implant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Artificial Tears Versus Preservative Free Ketorolac Trometamol 0.45% for Acute Viral Conjunctivitis
Status: COMPLETED
Conditions: Conjunctivitis, Viral
Interventions: DRUG: Ketorolac trometamol 0.45% with carboxymethylcellulose|DRUG: Preservative free artificial tear
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Signal-averaged ElectrocArdiogram in Long Term Follow-up of Chronic CHagas Disease - RIO de Janeiro Cohort
Status: COMPLETED
Conditions: Chagas Cardiomyopathy|Cardiac Arrhythmia|Stroke|Left Ventricular Function Systolic Dysfunction|Cardiac Death
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Oral Azacitidine (CC-486) Epigenetic Priming and Maintenance for Adult Acute Myeloid Leukemia (AML) Patients
Status: WITHDRAWN
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: oral azacitidine (CC-486)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ABLATE Post Approval Study - Synergy Ablation Lesions for Non-Paroxysmal Atrial Fibrillation
Status: COMPLETED
Conditions: Persistent Atrial Fibrillation|Longstanding Persistent Atrial Fibrillation
Interventions: DEVICE: Synergy Ablation System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Sensory-Motor Integration Training in Patients With Idiopathic Parkinson's Disease
Status: RECRUITING
Conditions: Idiopathic Parkinson Disease
Interventions: OTHER: Sensory-Motor Integration Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study on the Safety of CNT-02 for TGCV and NLSD-M
Status: TERMINATED
Conditions: Primary Triglyceride Deposit Cardiomyovasculopathy (TGCV)|Neutral Lipid Storage Disease With Myopathy (NLSD-M)
Interventions: DIETARY_SUPPLEMENT: CNT-02
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combining Non-Invasive Brain Stimulation With Cognitive Behavioral Intervention in Substance Use Disorder
Status: WITHDRAWN
Conditions: Active tDCS|Sham tDCS
Interventions: DEVICE: Active tDCS stimulation|DEVICE: Sham tDCS stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Curcumin and EGCG Supplementation to Improve Serum BDNF and Mood Disturbance
Status: NOT_YET_RECRUITING
Conditions: Mood Disturbance
Interventions: DIETARY_SUPPLEMENT: Curcumin|DIETARY_SUPPLEMENT: Epigallocatechin Gallate|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Implantable Microdevice for In Vivo Drug Sensitivity Testing in Patients With Early Stage, HER2-Positive or Triple Negative Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DEVICE: KIBUR MICRODEVICE|DRUG: anthracycline and taxane based chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Nelfinavir, Cisplatin, and External Beam Radiation Therapy for the Treatment of Locally Advanced Vulvar Cancer That Cannot Be Removed by Surgery
Status: RECRUITING
Conditions: Stage II Vulvar Cancer AJCC v8|Stage III Vulvar Cancer AJCC v8|Stage IIIA Vulvar Cancer AJCC v8|Stage IIIB Vulvar Cancer AJCC v8|Stage IIIC Vulvar Cancer AJCC v8|Stage IVA Vulvar Cancer AJCC v8
Interventions: DRUG: Cisplatin|RADIATION: External Beam Radiation Therapy|DRUG: Nelfinavir
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Co-admin of Colesevelam and Sitagliptin on Glucose Metabolism in Subjects With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Colesevelam HCl|DRUG: Sitagliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diagnosing Pulmonary Aspergillosis in Patients With Hematological Malignancies: A Multicentre Prospective Evaluation of an Aspergillus PCR Assay and a Galactomannan ELISA in Bronchoalveolar Lavage Samples
Status: COMPLETED
Conditions: Invasive Aspergillosis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Addition of Nivolumab to Anti-CD-19 CAR-T Cells in Patients With Stable/Progressive DLBCL at Lymphodepletion
Status: RECRUITING
Conditions: B Cell Lymphoma
Interventions: DRUG: Nivolumab Injection [Opdivo]
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: THE EFFICACY OF RESORBABLE PLATES VERSUS TITANIUM PLATES IN TERMS OF STABILITY IN MANDIBULAR FRACTURES.
Status: UNKNOWN
Conditions: Comparison of Resorbable Plates With Titanium Plates
Interventions: PROCEDURE: surgically mandible will be exposed to reduced the fracture anatomically and then fixated with either resorbable or the titanium plates
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT