pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: An Investigation of the Mechanism of Action of Seretide in Chronic Obstructive Pulmonary Disease
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Seretide 500 Accuhaler
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Phase 2a Safety and Efficacy Open-Label Study of PRA023 in Subjects With Moderately to Severely Active Crohn's Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Crohn Disease
Interventions: DRUG: PRA023 IV|DEVICE: Companion diagnostic (CDx)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: FLAVIOLA Health Study
Status: COMPLETED
Conditions: Vascular Health
Interventions: DIETARY_SUPPLEMENT: Flavanol (410 mg)|DIETARY_SUPPLEMENT: Control (no flavanols)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Delta Shock Index in Predicting Massive Transfusion
Status: COMPLETED
Conditions: Trauma Patients Received Blood Transfusion ≥ 10 U|Trauma Patients Had Not Received Blood Transfusion ≥ 10 U
Interventions: OTHER: Massive transfusion|OTHER: Non-Massive Transfusion
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Multidisciplinary Prehabilitation and Postoperative Rehabilitation in Patients Undergoing Resection of Colon Cancer
Status: ENROLLING_BY_INVITATION
Conditions: Colon Cancer|Postoperative Complications
Interventions: BEHAVIORAL: Prehabilitation program (4 week before the surgery)|BEHAVIORAL: Postoperative program (12 week after the surgery)|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Centella Asiatica (Gotukola) Mouthwash as an Adjunct to Mechanical Plaque Control
Status: COMPLETED
Conditions: Gingival Diseases
Interventions: DRUG: Gotukola|PROCEDURE: Scaling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dexmedetomidine (Precedex®) for Severe Alcohol Withdrawal Syndrome (AWS) and Alcohol Withdrawal Delirium (AWD)
Status: TERMINATED
Conditions: Alcohol Withdrawal Delirium|Alcohol Withdrawal Associated Autonomic Hyperactivity|Alcohol Withdrawal Hallucinosis|Alcohol Withdrawal-Induced Delirium Tremens
Interventions: DRUG: Dexmedetomidine|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Intrapulmonary Pharmacokinetics of Cefepime and Taniborbactam in Healthy Subjects
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: cefepime-taniborbactam
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Digital Individualized and Collaborative Treatment of T2D in General Practice Based on Decision Aid
Status: NOT_YET_RECRUITING
Conditions: Diabetes type2
Interventions: BEHAVIORAL: Clinical decision support|BEHAVIORAL: Digital Lifestyle Coaching|BEHAVIORAL: Integration to Standard Electronic Health Record
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Remifentanil Versus Morphine for Sedation of Premature Neonates With Respiratory Distress Syndrome
Status: COMPLETED
Conditions: Respiratory Distress Syndrome
Interventions: DRUG: Remifentanil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Dual-task Training Under Different Priority Instructions on Gait Speed in Community-dwelling Older Adults
Status: COMPLETED
Conditions: Gait|Postural Balance
Interventions: OTHER: Dual task with variable- and fixed-priority instructions|OTHER: Dual-task with variable-priority instructions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vorinostat, Cytarabine, and Etoposide in Treating Patients With Relapsed and/or Refractory Acute Leukemia or Myelodysplastic Syndromes or Myeloproliferative Disorders
Status: COMPLETED
Conditions: Accelerated Phase Chronic Myelogenous Leukemia|Adult Acute Basophilic Leukemia|Adult Acute Eosinophilic Leukemia|Adult Acute Megakaryoblastic Leukemia (M7)|Adult Acute Minimally Differentiated Myeloid Leukemia (M0)|Adult Acute Monoblastic Leukemia (M5a)|Adult Acute Monocytic Leukemia (M5b)|Adult Acute Myeloblastic Leukemia With Maturation (M2)|Adult Acute Myeloblastic Leukemia Without Maturation (M1)|Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities|Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)|Adult Acute Myeloid Leukemia With t(15;17)(q22;q12)|Adult Acute Myeloid Leukemia With t(16;16)(p13;q22)|Adult Acute Myeloid Leukemia With t(8;21)(q22;q22)|Adult Acute Myelomonocytic Leukemia (M4)|Adult Acute Promyelocytic Leukemia (M3)|Adult Erythroleukemia (M6a)|Adult Pure Erythroid Leukemia (M6b)|Atypical Chronic Myeloid Leukemia, BCR-ABL1 Negative|Blastic Phase Chronic Myelogenous Leukemia|Chronic Eosinophilic Leukemia|Chronic Myelomonocytic Leukemia|Chronic Neutrophilic Leukemia|de Novo Myelodysplastic Syndromes|Essential Thrombocythemia|Myelodysplastic/Myeloproliferative Neoplasm, Unclassifiable|Polycythemia Vera|Previously Treated Myelodysplastic Syndromes|Primary Myelofibrosis|Recurrent Adult Acute Lymphoblastic Leukemia|Recurrent Adult Acute Myeloid Leukemia|Relapsing Chronic Myelogenous Leukemia|Secondary Acute Myeloid Leukemia|Secondary Myelodysplastic Syndromes
Interventions: DRUG: vorinostat|DRUG: cytarabine|DRUG: etoposide|OTHER: pharmacological study|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective, Randomized, Multi-center Clinical Study of Plasma Disc Decompression
Status: COMPLETED
Conditions: Radicular Pain
Interventions: DEVICE: Perc-DLR/Perc-DLG|DRUG: Fluoroscopy guided transforaminal epidural steroid injection (TFESI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: H-9926-LCH III: Treatment Protocol of the Third International Study for Langerhans Cell Histiocytosis
Status: WITHDRAWN
Conditions: Leukemia
Interventions: DRUG: Prednisone, Vinblastin, 6-mercaptopuroine|DRUG: Leucovorin, Methotrexate, Vinblastine, Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Palatability of Experimental Cigarettes - Study 2
Status: COMPLETED
Conditions: Smoking
Interventions: OTHER: Low level nicotine cigarette|OTHER: Intermediate nicotine level cigarette|OTHER: High level nicotine cigarette
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: PMEG for Repair of Pararenal and Thoracoabdominal Aortic Aneurysm
Status: RECRUITING
Conditions: Pararenal Aortic Aneurysm|Thoracoabdominal Aortic Aneurysm
Interventions: DEVICE: PMEG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Photobiomodulation Therapy on Inflammatory Mediators on Low Back Pain
Status: COMPLETED
Conditions: Low Back Pain
Interventions: DEVICE: Placebo PBMT|DEVICE: Active PBMT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: No Power Bionic Lower Extremity Prosthesis
Status: COMPLETED
Conditions: Amputation|Amputation, Traumatic|Amputation; Traumatic, Leg, Lower
Interventions: DEVICE: Compliant Adaptive Energy Storage and Return Foot|DEVICE: AllPro
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: ADvance II Study: DBS-f in Patients With Mild Alzheimer's Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Alzheimer Disease
Interventions: DEVICE: DBS-f On|DEVICE: DBS Off
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cognitive Behavior Therapy for Health Anxiety: A Comparison of Three Forms of Self-help
Status: COMPLETED
Conditions: Severe Health Anxiety|Somatic Symptom Disorder|Illness Anxiety Disorder
Interventions: BEHAVIORAL: Cognitive Behavior Therapy, exposure and response prevention (Internet, guided)|BEHAVIORAL: Cognitive Behavior Therapy, exposure and response prevention (Internet, unguided)|BEHAVIORAL: Cognitive Behavior Therapy, exposure and response prevention (Book, unguided)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Photodynamic Therapy for COVID-19 Prevention
Status: COMPLETED
Conditions: COVID-19 Respiratory Infection|SARS-CoV-2 Acute Respiratory Disease
Interventions: DEVICE: Nasal Photodisinfection|DEVICE: Sham Comparator: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: LCI-LUN-ABR-001: Carbo With Nab-Paclitaxel in Patients With Advanced NSCL Cancer
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DRUG: Carboplatin|DRUG: Abraxane
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of Ramosetron in the Setting of Hematopoietic Stem Cell Transplantation
Status: UNKNOWN
Conditions: Hematologic Malignancies
Interventions: DRUG: ramosetron
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Remote Ischemic Conditioning Combined With Endovascular Stenting for Symptomatic Intracranial Atherosclerotic Stenosis
Status: NOT_YET_RECRUITING
Conditions: Intracranial Arteriosclerosis|Ischemic Preconditioning|Endovascular Procedures
Interventions: OTHER: Remote Ischemic Conditioning
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The RE-ENERGIZE Study: RandomizEd Trial of ENtERal Glutamine to minimIZE Thermal Injury
Status: UNKNOWN
Conditions: Burns
Interventions: DIETARY_SUPPLEMENT: Enteral Glutamine|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Measurement and Analysis of Gas Composition in Digestive Tract
Status: NOT_YET_RECRUITING
Conditions: Inflammatory Bowel Diseases|Irritable Bowel Syndrome|Functional Dyspepsia|Colorectal Neoplasms|Helicobacter Pylori Infection
Interventions: OTHER: gas component of digestive tract
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effectiveness of Non-invasive Vagus Nerve Stimulation as an Adjuvant Treatment in Patients With Sepsis in Intensive Care.
Status: RECRUITING
Conditions: Sepsis|Septic Shock
Interventions: OTHER: SNV activ group (Non-invasive transcutaneous stimulation of the vagus nerve )|OTHER: Placebo group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Efficacy of Shortwave Diathermy in Ulnar Nerve Entrapment on the Elbow
Status: COMPLETED
Conditions: Ulnar Nerve Entrapment at Elbow
Interventions: OTHER: shortwave diathermy treatment|OTHER: placebo shortwave diathermy treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hormonal and Inflammatory Changes During Pregnancy in Women With Glucose Metabolic Disorders.
Status: RECRUITING
Conditions: Diabetes Mellitus, Type 2|Gestational Diabetes|Overweight and Obesity|Pregnancy in Diabetic|Insulin Resistance|Insulin Sensitivity|Pregnancy, High Risk
Interventions: OTHER: No interventions
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Twelve Week Study of Virtually Supervised Mouth Rinse and Flossing
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: Listerine Cool Mint|OTHER: Colgate Cavity Protection Toothpaste|OTHER: Reach Unflavored Waxed Dental Floss|OTHER: American Dental Association (ADA) Ref Toothbrush
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: OTHER
Clinical trial: ACTHAR Gel for Cutaneous Sarcoidosis: An Open Label Trial
Status: UNKNOWN
Conditions: Sarcoidosis|Cutaneous Sarcoidosis
Interventions: DRUG: ACTHAR Gel 40 units twice weekly|DRUG: ACTHAR Gel 80 units twice weekly.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness and Safety of Mesenchymal Stem Cell (MSC) Implantation on Degenerative Discus Disease Patients
Status: UNKNOWN
Conditions: Degenerative Disc Disease|Low Back Pain|Disc Degeneration
Interventions: DRUG: Mesenchymal Stem Cell + NaCl 0,9% 2ml
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nasal Decolonization of Dialysis Patients Noses
Status: ACTIVE_NOT_RECRUITING
Conditions: Staphylococcus Aureus Infection
Interventions: DRUG: Povidone-Iodine Topical Ointment|OTHER: Standard Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Left Atrial Imaging Prior to Cardioversion: Leveraging Computed Tomography to Rule Out Thrombus
Status: RECRUITING
Conditions: Atrial Fibrillation
Interventions: DIAGNOSTIC_TEST: Contrast enhanced ECG-gated cardiac CT (CCT)|DIAGNOSTIC_TEST: Transesophageal Echocardiography (TEE)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Combined Effect of Pregabalin and Oxycodone, and Lacosamide and Oxycodone, on Breathing
Status: COMPLETED
Conditions: Opioid-induced Respiratory Depression
Interventions: DRUG: Pregabalin 150mg|DRUG: Oxycodone 10mg|DRUG: Lacosamide 150 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluating the Incidence of Pseudo-Acute Kidney Injuries in Patients With Metastatic Breast Cancer on CDK4/6 Inhibitors Trough Cystatin C Analysis
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Breast Cancer
Interventions: OTHER: no intervention, observational study of AKI under CDK4/6 inhibitor treatment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Dexmedetomidine for Sedation of Endobronchial Ultrasound-guided Transbronchial Needle Aspiration
Status: COMPLETED
Conditions: Bronchoscopy
Interventions: DRUG: Dexmedetomidine arm|DRUG: Propofol arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Comparison of Alemtuzumab and Rebif® Efficacy in Multiple Sclerosis, Study Two
Status: COMPLETED
Conditions: Multiple Sclerosis, Relapsing-Remitting
Interventions: BIOLOGICAL: Alemtuzumab 12 mg|BIOLOGICAL: Alemtuzumab 24 mg|BIOLOGICAL: Interferon beta-1a
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cetuximab + / - Carboplatin for Estrogen Receptor-Negative, Progesterone Receptor-Negative Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: BIOLOGICAL: cetuximab|DRUG: carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: STUDIIO-Diabetes Pilot: STUdy of Drug Insurance to Improve Outcomes of Diabetes
Status: NOT_YET_RECRUITING
Conditions: Type 2 Diabetes Mellitus|Medication Adherence|Medication Compliance|Medication Nonadherence
Interventions: OTHER: No-cost Medications
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: B1 and Magnesium Supplements on Glucose Metabolism in Low-carb Dieters
Status: SUSPENDED
Conditions: Diet, Carbohydrate-restricted
Interventions: DIETARY_SUPPLEMENT: vitamin B1 and magnesium supplements
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Marsupialization of Anal Fistulotomy Wound Accelerates Healing and Decreases Post Operative Pain
Status: COMPLETED
Conditions: Anal Fistula
Interventions: PROCEDURE: fistulotomy and marsupialization of wound edges|PROCEDURE: fistulotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Approaches For ThE pRioritization of Patients in priMAry Care Post-COVID To Reduce Health Inequities (AFTERMATH)
Status: NOT_YET_RECRUITING
Conditions: Schizophrenia|Bipolar Disorder
Interventions: OTHER: Community Health Worker
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Relieving Pain and Improving Sleep: Evaluating Topical Pain Relief and Sleep Patches
Status: NOT_YET_RECRUITING
Conditions: Pain, Back|Pain, Acute|Sleep Disorder|Sleep Disorders, Circadian Rhythm|Sleep|Sleep Deprivation|Insomnia
Interventions: DEVICE: Drug- free, non-invasive patch (FREEDOM or REM Patch) with haptic vibrotactile trigger technology (VTT) Other Names:|DEVICE: Sham Patch without haptic vibrotactile trigger technology (VTT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Comparison of 27+® and 23-gauge ULTRAVIT® 7500 Cpm Vitrectomy Outcomes
Status: COMPLETED
Conditions: Vitreoretinal Disease
Interventions: DEVICE: CONSTELLATION® 27-gauge Combined Surgical Pak|DEVICE: CONSTELLATION® 23-gauge Combined Surgical Pak|PROCEDURE: Vitrectomy surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evolution of Albumin on AOA1 Patients Supplemented With Coenzyme Q10
Status: COMPLETED
Conditions: Ataxia-oculomotor Apraxia 1
Interventions: DIETARY_SUPPLEMENT: CoQ10|OTHER: Sanomit Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Detoxification of the Liver In PSC (Dolphin)
Status: RECRUITING
Conditions: Primary Sclerosing Cholangitis
Interventions: DRUG: BRS201|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: GM-CSF Vaccinations After Allogeneic Blood Stem Cell Transplantation in Patients With Advanced Myeloid Malignancies
Status: COMPLETED
Conditions: Myelodysplastic Syndrome RAEB-I or RAEB-II|Refractory Acute Myeloid Leukemia|Refractory CML Myeloid Blast Crisis
Interventions: BIOLOGICAL: GM-CSF secreting leukemia vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Personalized Rituximab Treatment Based on Artificial Intelligence in Membranous Nephropathy (iRITUX)
Status: NOT_YET_RECRUITING
Conditions: Membranous Nephropathy
Interventions: DRUG: RiTUXimab Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study of TAB006 in Patients With Previously Treated, Advanced Malignancies
Status: WITHDRAWN
Conditions: Previously Treated, Advanced|Malignancies
Interventions: DRUG: TAB006|DRUG: Toripalimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ICCRT vs. CRT for Locally Advanced Nasopharyngeal Carcinoma
Status: RECRUITING
Conditions: Locally Advanced Nasopharyngeal Carcinoma
Interventions: DRUG: Induction Chemotherapy|DRUG: Concurrent Chemotherapy|RADIATION: Definitive Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Predicting SSRI Efficacy in Veterans With PTSD
Status: RECRUITING
Conditions: Posttraumatic Stress Disorder|Major Depressive Disorder
Interventions: DIAGNOSTIC_TEST: LDAEP|DRUG: Placebo|DRUG: sertraline
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Prospective Study of Adjunctive Carotenoids Plus Anti-oxidants in Anti-VEGF Treated Diabetic Macular Edema
Status: UNKNOWN
Conditions: Center-involved Diabetic Macular Edema (CI-DME)
Interventions: DIETARY_SUPPLEMENT: Diabetes Visual Function Study (DiVFuSS) softgels|OTHER: canola oil placebo softgels, 2 per day
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Dose-Escalation Study of GDC-0994 in Patients With Locally Advanced or Metastatic Solid Tumors
Status: COMPLETED
Conditions: Solid Tumor
Interventions: DRUG: GDC-0994|DRUG: GDC-0994
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Pharmacokinetic and Safety Study of Lower Doses of Ceritinib Taken With a Low-fat Meal Versus 750 mg of Ceritinib in the Fasted State in Adult Patients With (ALK-positive) Metastatic Non-small Cell Lung Cancer (NSCLC)
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: ceritinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vit D and Post-extractive Bone Turnover
Status: COMPLETED
Conditions: Vitamin D Deficiency|Alveolar Bone Loss|Alveolar Bone Resorption
Interventions: PROCEDURE: Tooth extraction, guided bone regeneration and dental implant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mechanism and Efficacy of Rehabilitation Approaches
Status: COMPLETED
Conditions: Cerebrovascular Accidents
Interventions: OTHER: Constraint-induced therapy (CIT)|OTHER: Bilateral arm training (BAT)|OTHER: Combined therapy (CT)|BEHAVIORAL: Control intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effective Feedback to Improve Primary Care Prescribing Safety
Status: COMPLETED
Conditions: Complications of Surgical and Medical Care: General Terms
Interventions: OTHER: Usual care|OTHER: Feedback of Performance|OTHER: Feedback of Performance + Health Psychology Informed Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Examination of Pain in Individuals With Non-Specific Lack Pain
Status: COMPLETED
Conditions: Back Pain|Balance|Proprioception
Interventions: OTHER: Visual Analogue Scale (VAS),|OTHER: Oswestry Low Back Pain and Disability Questionnaire|OTHER: Functional Low Back Pain Scale|DEVICE: Prokin TecnoBody isokinetic balance 2 device|DEVICE: EMG|DEVICE: Algometer|DEVICE: Goniometer
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Laryngoscopy and Coronary Artery Bypass Graft Surgery
Status: NOT_YET_RECRUITING
Conditions: Videolaryngoscopy
Interventions: OTHER: Tracheal intubation using Storz VL|OTHER: Tracheal intubation using Macintosh laryngoscopy|OTHER: Tracheal intubation using MacGrath VL|OTHER: Tracheal intubation using EzVision VL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effect of Pomegranate Peel Added Bread on Blood Sugar, Fats, and the Body's Defense Response
Status: UNKNOWN
Conditions: Type 2 Diabetes
Interventions: DIETARY_SUPPLEMENT: Pomegranate Peel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy and Tolerability of Cisplatin Plus Alternating Weekly Temozolomide in Recurrent High-grade Gliomas
Status: COMPLETED
Conditions: High-grade Gliomas
Interventions: DRUG: CDDP|DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess Safety, Tolerability and Immunogenicity of the Live Attenuated hRSV Vaccine rBCG-N-hRSV
Status: COMPLETED
Conditions: Respiratory Syncytial Virus Infections
Interventions: BIOLOGICAL: rBCG-N-hRSV 1/100|BIOLOGICAL: rBCG-N-hRSV 1/10|BIOLOGICAL: rBCG-N-hRSV full dose|BIOLOGICAL: Conventional BCG full dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Novel Treatment for Dental Ankylosis
Status: RECRUITING
Conditions: Dental Ankylosis
Interventions: DEVICE: Electric Toothbrush-Generated Vibration|DEVICE: Mini-Implant-Assisted Orthodontic Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ingestion of Simethicone After Capsule Ingestion and Its Impact on Quality of Video Capsule Endoscopy- a Pilot Study
Status: UNKNOWN
Conditions: Video Capsule Endoscopy
Interventions: DRUG: Simethicone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: MK-2060 and Clopidogrel Co-administration Safety and Tolerability Study in Participants With End-Stage Renal Disease (ESRD) (MK-2060-008)
Status: COMPLETED
Conditions: End-Stage Renal Disease|Kidney Failure, Chronic
Interventions: DRUG: MK-2060
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Toileting at Night in Older Adults: Light to Maximize Balance, Minimize Insomnia
Status: COMPLETED
Conditions: Falls|Balance|Insomnia|Aging
Interventions: BEHAVIORAL: White light exposure|BEHAVIORAL: Dim white light exposure|BEHAVIORAL: Very dim white light exposure|BEHAVIORAL: Dim orange light exposure
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Technetium Tc 99m Demobesin-4 for Imaging Procedures in Patients With Prostate Cancer
Status: TERMINATED
Conditions: Prostate Cancer
Interventions: OTHER: immunohistochemistry staining method|OTHER: laboratory biomarker analysis|OTHER: pharmacological study|PROCEDURE: computed tomography|PROCEDURE: magnetic resonance imaging|PROCEDURE: single photon emission computed tomography|RADIATION: technetium Tc 99m demobesin-4
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Bilateral vs. Unilateral Neuromobilization in Carpal Tunnel Syndrome
Status: RECRUITING
Conditions: Carpal Tunnel Syndrome
Interventions: OTHER: Unilateral Intervention|OTHER: Bilateral Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Selenium as an Alternative or Complementary Topical Treatment of Oral Lichen Planus
Status: NOT_YET_RECRUITING
Conditions: Lichen Planus, Oral
Interventions: DRUG: Triamcinolone Acetonide 0.1% Oint|DRUG: Tacrollimus Topical|DRUG: Selenium|DRUG: Selenium & Triamcinolone Acetonide 0.1% Oint|DRUG: Selenium& Tacrollimus topical
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study of Varencline Effects on Cigarette Smoking Reward and Craving During a Model of Brief Quit Attempt
Status: WITHDRAWN
Conditions: Nicotine Dependence
Interventions: DRUG: varencline|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: PK & PD Study of Pegylated rhEPO, and Evaluated Its Safety and Tolerability in Male Healthy Individual
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Pegylated rhEPO|DRUG: EPIAO®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: The Study is Designed to Evaluate Single Ascending Doses of AR882 in Healthy Adult Males
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Cohort 1: AR882|DRUG: Cohort 2: AR882|DRUG: Cohort 3: AR882|DRUG: Cohort 4: AR882|DRUG: Cohort 5: AR882|DRUG: Cohort 6: AR882 Food Effect|DRUG: Cohort 7: AR882 Solid Oral Formulation|DRUG: Cohort 8: AR882 in combination with allopurinol|DRUG: Cohort 9: AR882 in combination with febuxostat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Neutralization of Endogenous Acid Production on BMD and Bone Microarchitectural
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: potassium citrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Sevoflurane Consumption During General Anesthesia When Using the MemsorbTM Membrane
Status: COMPLETED
Conditions: Laparoscopic General, Gynecological and Urologic Surgeries
Interventions: DEVICE: To evaluate sevoflurane consumption when using Memsorb|DEVICE: To evaluate sevoflurane consumption when using classical Dräegersorb
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Combined Spinal Epidural Anaesthesia on QTc Interval Undergoing Cesarean Section
Status: RECRUITING
Conditions: Analgesia
Interventions: OTHER: BMI≥30; Combined Spinal Epidural Anesthesia|OTHER: BMI:18,5-24,9; Combined Spinal Epidural Anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Patient Education Video Program for Post-Operative Recovery After Upper Extremity Surgery
Status: UNKNOWN
Conditions: Analgesics, Opioid|Orthopedic Surgery|Ambulatory Surgery|Education, Patient|Injuries and Wounds
Interventions: BEHAVIORAL: Pain Management Patient Education Video|BEHAVIORAL: Wound Care Patient Education Video
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluate the Safety, Immunogenicity and Potential Efficacy of an rVSV-SARS-CoV-2-S Vaccine
Status: COMPLETED
Conditions: Covid19
Interventions: BIOLOGICAL: IIBR-100, low dose (prime)|BIOLOGICAL: IIBR-100 medium dose (prime)|BIOLOGICAL: IIBR-100 high-dose (prime)|BIOLOGICAL: IIBR-100 low-dose (prime-boost)|OTHER: Saline Placebo (single)|OTHER: Saline Placebo (double)|BIOLOGICAL: IIBR-100 medium-dose (prime-boost)|BIOLOGICAL: IIBR-100 high-dose (prime-boost)|BIOLOGICAL: IIBR-100 top-dose (prime-boost)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Intravenous Paracetamol in Combination With Caudal Ropivacaine
Status: COMPLETED
Conditions: Postoperative Analgesia
Interventions: DRUG: Paracetamol +caudal ropivacaine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigating Age Dependence of Fibroblast and Extracellular Matrix Responses to Cross-linked Hyaluronic Acid Filler in Human Skin
Status: RECRUITING
Conditions: Photoaging
Interventions: DEVICE: Restylane-L|DEVICE: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Dry Cupping and Ischemic Compression on the Trigger Point on the Upper Trapezius Muscle
Status: COMPLETED
Conditions: Trigger Point Pain, Myofascial
Interventions: OTHER: 1) cupping therapy|OTHER: 2) control test (no intervention)|OTHER: 3) ischemic compression
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: LiquiBand Versus Dermabond Versus Sutures for Closure of Surgical Wounds
Status: COMPLETED
Conditions: Surgical Incisions
Interventions: DEVICE: LiquiBand Flex|DEVICE: Dermabond Advanced|DEVICE: Sutures (Prolene)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Gait Performance and Brain Activity After Robot-assisted Gait Training (RAGT) On Patients With Lower Extremity Thermal Injury
Status: NOT_YET_RECRUITING
Conditions: Gait Disorder, Sensorimotor
Interventions: OTHER: robot assited gati training|OTHER: conventional traiing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: NOACs for Stroke Prevention in Patients With Atrial Fibrillation and Previous ICH
Status: COMPLETED
Conditions: Atrial Fibrillation|Intracerebral Hemorrhage
Interventions: DRUG: NOAC|DRUG: Acetylsalicylic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An EFS Assessing the Electrolytic eCLIPs System for Treatment of Intracranial Aneurysms
Status: WITHDRAWN
Conditions: Aneurysm, Intracranial
Interventions: DEVICE: Electrolytic eCLIPs Bifurcation System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Quantum Molecular Resonance (QMR) Rehabiltative Treatment of Knee Osteoarthritis
Status: COMPLETED
Conditions: Knee Pain Chronic
Interventions: DEVICE: QMR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pre-operAtive Non-Anthracycline Chemotherapy, Durvalumab +/- RAdiation Therapy in Triple Negative Breast Cancer
Status: WITHDRAWN
Conditions: Breast Cancer|Triple Negative Breast Cancer
Interventions: DRUG: Durvalumab|RADIATION: Radiation Therapy|DRUG: Carboplatin|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of a Quadrivalent Meningococcal Conjugate Vaccine When Administered Concomitantly With Routine Pediatric Vaccines in Healthy Infants and Toddlers in the Russian Federation and Mexico
Status: COMPLETED
Conditions: Healthy Volunteers (Meningococcal Infection)
Interventions: BIOLOGICAL: Meningococcal Polysaccharide (Serogroups A, C, Y, and W) Tetanus Toxoid Conjugate Vaccine|BIOLOGICAL: Meningococcal (Groups A, C, Y and W 135) Oligosaccharide Diphtheria CRM197 Conjugate Vaccine|BIOLOGICAL: Measles, Mumps, and Rubella Virus Vaccine Live|BIOLOGICAL: Pneumococcal 13-valent Conjugate Vaccine|BIOLOGICAL: Diphtheria, Tetanus, Pertussis (Acellular, Component) Poliomyelitis (inactivated) Vaccine, and Haemophilus influenza type b Conjugate Vaccine|BIOLOGICAL: Hepatitis B Vaccine|BIOLOGICAL: Rotavirus Vaccine, Live, Pentavalent|BIOLOGICAL: Diphtheria, tetanus, pertussis (acellular component), hepatitis B, poliomyelitis (inactivated), and Haemophilus influenzae type b conjugate vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Pulse Versus Continuous Cyclophosphamide for Induction of Remission in ANCA-Associated Vasculitides
Status: COMPLETED
Conditions: ANCA Associated Systemic Vasculitis|Wegener's Granulomatosis|Microscopic Polyangiitis
Interventions: DRUG: cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Spontaneous Breathing Trial With T-piece or Inspiratory Pressure Augmentation
Status: RECRUITING
Conditions: Ventilator Weaning
Interventions: DIAGNOSTIC_TEST: Spontaneous breathing trial (SBT) crossover sequence 1|DIAGNOSTIC_TEST: Spontaneous breathing trial (SBT) crossover sequence 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Impact of Culture Conditions on the Embryo Quality
Status: COMPLETED
Conditions: Embryo Development
Interventions: PROCEDURE: Standard incubator|PROCEDURE: Mini incubator|PROCEDURE: 5% oxygen|PROCEDURE: 20% oxygen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Tenofovir in Early Pregnancy to Prevent Mother-to-child Transmission of Hepatitis B Virus
Status: COMPLETED
Conditions: Hepatitis B
Interventions: DRUG: Tenofovir Disoproxil Fumarate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: NEO-PTC-01 in Patients With Advanced or Metastatic Melanoma
Status: RECRUITING
Conditions: Unresectable Melanoma|Metastatic Melanoma
Interventions: BIOLOGICAL: NEO-PTC-01|DRUG: IL-2|DRUG: αPD-1 therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Intradiscal Injection of Autologous BM-MSC in Worker Patients Affected by Chronic LBP Due to Multilevel IDD
Status: ACTIVE_NOT_RECRUITING
Conditions: Intervertebral Disc Degeneration|Chronic Low-back Pain
Interventions: DRUG: Autologous BM-MSC|OTHER: Sham Procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Diabetes and Aquatic Training Study (DATS)
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: OTHER: Aerobic training|OTHER: Combined training|OTHER: Training placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Veliparib, Cyclophosphamide, and Doxorubicin Hydrochloride in Treating Patients With Metastatic or Unresectable Solid Tumors or Non-Hodgkin Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Ann Arbor Stage III Non-Hodgkin Lymphoma|Ann Arbor Stage IV Non-Hodgkin Lymphoma|Solid Neoplasm
Interventions: DRUG: Cyclophosphamide|DRUG: Doxorubicin Hydrochloride|OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacological Study|DRUG: Veliparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Determine the Safety and Efficacy of a New Non-invasive Heating Garment to Reduce Urinary Hesitancy
Status: COMPLETED
Conditions: Benign Prostatic Hyperplasia (BPH)|Urinary Retention|Urinary Hesitancy Intermittent
Interventions: DEVICE: FlowPants(R) Garment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Guo's Subclavian Artery Reconstruction: The Prospective, Multiple Center Study of WeFlow-Tbranch Stent Graft System(GUEST Study)
Status: ACTIVE_NOT_RECRUITING
Conditions: Type B Aortic Dissection
Interventions: DEVICE: WeFlow-Tbranch Stent Graft System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Esketamine as Treatment for Chronic Pain Due to Endometriosis: a RCT Study
Status: RECRUITING
Conditions: Endometriosis|Chronic Pelvic Pain Syndrome
Interventions: DRUG: Esketamine hydrochloride|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Postoperative Nausea and Vomiting After Laparoscopic Cholecystectomy
Status: COMPLETED
Conditions: Postoperative Nausea|Postoperative Vomiting
Interventions: DRUG: midazolam and palonosetron group|DRUG: palonosetron group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Role of Sustained Inflation on Short Term Respiratory Outcomes in Term Infants
Status: COMPLETED
Conditions: Respiratory Distress Syndrome, Newborn|Transient Tachypnea of the Newborn|Respiratory Morbidity
Interventions: OTHER: Sustained Inflation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy Study of Transcranial Magnetic Stimulation for Treatment of Obsessive-Compulsive Disorder
Status: COMPLETED
Conditions: Obsessive Compulsive Disorder
Interventions: DEVICE: Repetitive Transcranial Magnetic Stimulation (rTMS)|DEVICE: Sham repetitive transcranial magnetic stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: N-Acetyl Cysteine Plus Behavioral Therapy for Nicotine Dependent Pathological Gamblers
Status: COMPLETED
Conditions: Gambling|Tobacco Use Disorder
Interventions: DRUG: N Acetyl Cysteine|OTHER: Sugar Pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Regenerative Medicine for COVID-19 and Flu-Elicited ARDS Using Lomecel-B (RECOVER)
Status: ACTIVE_NOT_RECRUITING
Conditions: ARDS, Human|Covid19
Interventions: BIOLOGICAL: Longeveron Mesenchymal Stem Cells (LMSCs)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Visible vs. Non-Visible Mesh in Underlay Positon After Repair of Umbilical Hernias
Status: COMPLETED
Conditions: Umbilical Hernia
Interventions: DEVICE: DynaMeshVisible|DEVICE: DynaMeshCICAT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Reactogenicity and Immunogenicity of HB-502 and HB-501 Versus Placebo in People With HIV on Suppressive ART
Status: RECRUITING
Conditions: Human Immunodeficiency Virus (HIV) Infection
Interventions: BIOLOGICAL: HB-502 and HB-501 alternating 2-vector therapy Dose Level 1|BIOLOGICAL: HB-502 and HB-501 alternating 2-vector therapy Dose Level 2|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Surgical Removal of Visceral Fat Tissue (Omentectomy) Associated to Bariatric Surgery: Effects on Insulin Sensitivity
Status: COMPLETED
Conditions: Insulin Resistance|Obesity|Metabolic Syndrome X
Interventions: PROCEDURE: Roux-en-Y Gastric Bypass plus total omentectomy|PROCEDURE: Roux-en-Y Gastric Bypass
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Brentuximab Vedotin in High-Risk CD30+ Lymphoma Post Allogeneic Stem Cell Transplantation (AlloSCT)
Status: TERMINATED
Conditions: Lymphoma
Interventions: DRUG: Brentuximab Vedotin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Bifidobacterium Combined With High-frequency Transcranial Magnetic Stimulation in the Treatment of Adolescent Depression
Status: COMPLETED
Conditions: Adolescent Depression
Interventions: DRUG: Bifidobacterium|DEVICE: High-frequency rTMS|DRUG: Escitalopram Oxalate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Retention Rate of Hydroxyapatite Nano-Fiber Reinforced Flowable Composite Versus Conventional
Status: UNKNOWN
Conditions: Retention Rate of Flowable Composite in Demenerlized Pits and Fissure
Interventions: OTHER: Hydroxyapatite Nanofiber reinforced flowable composite|OTHER: conventional resin-based flowable composite
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER