pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Prevention of Hypoglycaemia With Predictive Insulin Suspend Using Sensor Augmented Insulin Pump in Children
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus
Interventions: DEVICE: Medtronic MiniMed™ 640G system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Probiotics: is it Really That Good? Cost-Effectiveness of Treating the in-Patient
Status: UNKNOWN
Conditions: Diarrhea|Clostridium Difficile
Interventions: DRUG: probiotic mixture|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Outpatient Administration of High Dose Methotrexate (HD MTX) in Patients With Osteosarcoma
Status: COMPLETED
Conditions: Osteosarcoma
Interventions: DRUG: High Dose Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Short Against Long Antibiotic Therapy for Infected Orthopedic Sites
Status: RECRUITING
Conditions: Orthopedic Devices Associated With Misadventures|Infection, Surgical Site|Antibiotic Side Effect
Interventions: DRUG: Antibiotic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of SOT101 in Combination With Pembrolizumab to Evaluate the Efficacy and Safety in Patients With Selected Advanced Solid Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-Small Cell Lung Cancer|Colorectal Cancer|Cutaneous Squamous Cell Carcinoma|Hepatocellular Carcinoma|Castration-resistant Prostate Cancer|Ovarian Cancer
Interventions: DRUG: Nanrilkefusp Alfa|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Imaging Colo-rectal Cancer Using a Two Step Antibody Technique in Nuclear Imaging
Status: COMPLETED
Conditions: Colonic Neoplasms
Interventions: DRUG: Indium labeled IMP-205xm734
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Dermabond PRINEO for Total Shoulder Arthroplasty
Status: COMPLETED
Conditions: Surgical Wound|Shoulder Arthritis|Surgical Incision
Interventions: PROCEDURE: Subcuticular Sutures - Surgeon 1|PROCEDURE: Metal Staples - Surgeon 2|DEVICE: PRINEO - Surgeon 1|DEVICE: PRINEO - Surgeon 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Aprepitant and Granisetron for the Prophylaxis of Radiation Induced Nausea and Vomiting - A Pilot Study
Status: TERMINATED
Conditions: Nausea|Vomiting
Interventions: DRUG: Aprepitant|RADIATION: Palliative radiation therapy|DRUG: Granisetron
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Postprandial Effects of Milk Fats
Status: UNKNOWN
Conditions: Genomics|Postprandial Metabolism|Nutrition|Metabolism
Interventions: OTHER: 100% vegetable blend|OTHER: 100% AMF|OTHER: 100% cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Safety Study to Compare Formoterol Fumerate in the Pressair DPI to the Foradil Aerolizer in Patient With Mild to Moderate Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Formoterol Fumarate in the Pressair DPI, Low Dose|DRUG: Formoterol Fumarate in the Pressair DPI, High Dose|DRUG: Foradil Aerolizer, Low Dose|DRUG: Foradil Aerolizer, High Dose|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Foley OR MisO for the Management of Induction
Status: COMPLETED
Conditions: Delivery; Prolonged
Interventions: DEVICE: Cervical Foley & Misoprostol|DRUG: Misoprostol Alone|DEVICE: Cervical Foley Alone|DEVICE: Cervical Foley & Pitocin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Antiphospholipid Antibodies in Patients of Antiphospholipid Syndrome (APS) With Systemic Lupus Erythematosus (SLE).
Status: COMPLETED
Conditions: Anti-phospholipid Antibobodies in Patients of SLE Presenting With Thrombosis or Pregnancy Complications
Interventions: DIAGNOSTIC_TEST: Antibody testing
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: PpPfs25/ISA51 and ScPvs25/ISA51 Vaccines for Malaria
Status: COMPLETED
Conditions: Plasmodium Falciparum|Plasmodium Vivax Malaria
Interventions: DRUG: PpPfs25/ISA51 & ScPvs25/ISA51
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Lumbosciatic Syndrome: Vojta Therapy vs. TENS
Status: COMPLETED
Conditions: Lumbosciatic Syndrome|Pain|Functional Limitation|Vojta Therapy|Transcutaneous Electrical Nerve Stimulation
Interventions: OTHER: Physiotherapy technique: TENS|OTHER: Physiotherapy technique: Vojta Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Mixed Reality Technology-Based Breastfeeding Counseling on Breastfeeding Success and Self-Efficacy of Women
Status: NOT_YET_RECRUITING
Conditions: Breastfeeding|Breast Milk Expression|Pregnancy Related
Interventions: OTHER: Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Phase 3 Study to Evaluate the Efficacy and Safety of K-877 in Chinese Patients With High TG and Low HDL-C
Status: UNKNOWN
Conditions: Hyperlipidemia
Interventions: DRUG: K-877 0.1 mg tablet|DRUG: Fenofibrate 200 mg capsule|DRUG: Placebo tablet|DRUG: Placebo capsule|DRUG: K-877 0.1 mg tablet|DRUG: Placebo tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Anti-CD19-CD3E-CAR-T Cells in Relapsed/Refractory Autoimmune Disease
Status: RECRUITING
Conditions: Systemic Lupus Erythematosus (SLE)|Sjogren's Syndrome|Systemic Sclerosis|Inflammatory Myopathy|ANCA Associated Vasculitis|Antiphospholipid Syndrome
Interventions: BIOLOGICAL: Anti-CD19-CD3E-CAR-T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: NITRATE-OCT-CIN (Sub-Study of NITRATE-OCT)
Status: COMPLETED
Conditions: Cardiovascular Diseases
Interventions: DIETARY_SUPPLEMENT: Beetroot Juice|DIETARY_SUPPLEMENT: Beetroot Juice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: TOM: Testosterone in Older Men With Sarcopenia
Status: TERMINATED
Conditions: Sarcopenia|Hypogonadism|Muscular Diseases
Interventions: DRUG: Topical testosterone gel 1% (active formulation)|DRUG: Topical gel (placebo formulation)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The RESET Clinical Trial: SPRINT® Peripheral Nerve Stimulation for the Treatment of Back Pain
Status: ACTIVE_NOT_RECRUITING
Conditions: Low Back Pain|Back Pain
Interventions: DEVICE: SPRINT Peripheral Nerve Stimulation (PNS) System|PROCEDURE: Standard interventional management of low back pain
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: the Efficacy and Safety of a Modified Microfracture Using Collagen Compared to Those of a Simple Microfracture in Ankle
Status: UNKNOWN
Conditions: Defect of Articular Cartilage
Interventions: PROCEDURE: Microfracture|DEVICE: CartiFill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of RGX-202-01 (Ompenaclid) as Combination Therapy in RAS Mutant Advanced Colorectal Cancer
Status: RECRUITING
Conditions: Gastrointestinal Cancer|Gastrointestinal Neoplasms|Colorectal Cancer|Colorectal Neoplasms|Colorectal Carcinoma|Gastric Cancer|Gastric Neoplasm|KRAS Mutation-Related Tumors|CRC|Colorectal Cancer Metastatic
Interventions: DRUG: ompenaclid|DRUG: FOLFIRI|DRUG: Bevacizumab|DRUG: FOLFOX regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Peginterferon Alfa-2b (SCH 054031) vs Glycyrrhizin in Interferon (IFN)-Treated Patients With Chronic Hepatitis C and F2/F3 Liver Fibrosis (P04773)
Status: TERMINATED
Conditions: Hepatitis C, Chronic
Interventions: BIOLOGICAL: Peginterferon alfa-2b (PegIFN-2b)|DRUG: Comparator: Stronger neo minophagen C (SNMC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gemcitabine Plus Erlotinib in RASH-positive Patients With Metastatic Pancreatic Cancer
Status: UNKNOWN
Conditions: Metastatic Pancreatic Adenocarcinoma
Interventions: DRUG: Gemcitabine|DRUG: Erlotinib|DRUG: Oxaliplatin|DRUG: Folinic Acid|DRUG: Irinotecan|DRUG: 5-FU
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Short Clinical Outcome of Microscope Assisted Discectomy: Results of 90 Cases in Iraq
Status: COMPLETED
Conditions: To Evaluate the Effectiveness if Microscope in Discectomy
Interventions: PROCEDURE: Microscope assisted discectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Echocardiographic Measurement of Myocardial Work
Status: NOT_YET_RECRUITING
Conditions: Cardiovascular Physiological Phenomena|Intensive Care Unit Syndrome
Interventions: OTHER: Fluid administration|OTHER: Norepinephrine administration or increase in norepinephrine dosage
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Real-time Targeted Fluorescence Endoscopy for Detection of the Primary Cancer Lesion in Patients With a Metastasis of Unknown Primary Tumor in the Head and Neck
Status: RECRUITING
Conditions: Unknown Primary Tumors|Oropharynx Cancer
Interventions: DIAGNOSTIC_TEST: Detection of lesions using fluorescence molecular imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Vitoria Sleep Smart City: Interactive Intervention for Sleep Improvement
Status: COMPLETED
Conditions: Sleep Deprivation|Sleep Hygiene
Interventions: DEVICE: Live Chat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Toward Thriving: A Set of Reflective Tools to Empower Chronic Pain Patients and Help Them Envision a Personal Path to Thriving.
Status: COMPLETED
Conditions: Chronic Pain
Interventions: BEHAVIORAL: Self-guided at home activities
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Apalutamide Plus Cetrelimab in Patients With Treatment-Emergent Small Cell Neuroendocrine Prostate Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Small Cell Neuroendocrine Carcinoma|Prostate Cancer|Small Cell Carcinoma
Interventions: DRUG: Apalutamide|BIOLOGICAL: Cetrelimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Gene Therapy for Classic Congenital Adrenal Hyperplasia (CAH)
Status: RECRUITING
Conditions: Congenital Adrenal Hyperplasia
Interventions: BIOLOGICAL: AAV BBP-631
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Bruton's Tyrosine Kinase Inhibitor in Subjects With Relapsed or Relapsed and Refractory Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: PCI-32765|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GS3-007a Oral Solution in Healthy Subjects
Status: COMPLETED
Conditions: Healthy Subject
Interventions: DRUG: GS3-007 oral liquid or Placebo GS3-007 oral liquid oral medication
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Carboplatin, Pemetrexed, and Atezolizumab in Patients With Non-squamous Non-small Cell Lung Cancer (NSCLC) and Untreated Brain Metastases
Status: RECRUITING
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: Tiragolumab|DRUG: Atezolizumab|DRUG: Pemetrexed|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Zotarolimus vs Sirolimus Eluting Stent in High Bleeding Risk
Status: RECRUITING
Conditions: High Bleeding Risk|Coronary Artery Disease|Percutaneous Coronary Intervention
Interventions: DEVICE: Zotarolimus eluting stent|DEVICE: Sirolimus eluting stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Efficacy, Safety and Tolerability Study of Ixmyelocel-T Administered Via Transendocardial Catheter-based Injections to Subjects With Heart Failure Due to Ischemic Dilated Cardiomyopathy (IDCM)
Status: COMPLETED
Conditions: Ischemic Dilated Cardiomyopathy (IDCM)
Interventions: BIOLOGICAL: ixmyelocel-T|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Decision Support Tool
Status: UNKNOWN
Conditions: Medication Adherence|Hypertension|Decision Making, Shared|Patient-Centered Outcomes Research
Interventions: BEHAVIORAL: Control|BEHAVIORAL: Interview Only|BEHAVIORAL: Interview plus decision support tool
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Dose Escalation Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of Epelsiban Administered in Repeat Doses in Healthy Women Volunteers
Status: COMPLETED
Conditions: Embryo Transfer
Interventions: DRUG: Epelsiban (GSK557296)|DRUG: Placebo to match GSK557296
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Consistently Assess Signs and Symptom of Heart Failure
Status: RECRUITING
Conditions: Heart Failure|Heart Failure With Reduced Ejection Fraction|Heart Failure With Preserved Ejection Fraction
Interventions: OTHER: New York Heart Association Classification Guide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Validation of Renal Perfusion CEUS Against MRI, and Its Application in Acute Kidney Injury
Status: UNKNOWN
Conditions: Kidney Injury, Acute|Perfusion Imaging|Ultrasonography|Kidney Diseases
Interventions: DIAGNOSTIC_TEST: Contrast enhanced ultrasound|DIAGNOSTIC_TEST: Arterial Spin Labelling -Magnetic Resonance Imaging
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: FLASH [Fluorescent Light Activated Synthetic Hypericin] Clinical Study: Topical SGX301 (Synthetic Hypericin) for the Treatment of Cutaneous T-Cell Lymphoma (Mycosis Fungoides)
Status: COMPLETED
Conditions: Cutaneous T-Cell Lymphoma
Interventions: DRUG: SGX301 (synthetic hypericin)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Power Wheelchair Driving Performance Under Immersive and Non-immersive Conditions With Drivers With Neurological Disorders
Status: COMPLETED
Conditions: Neurologic Disorder|Brain Injuries|Neurodegeneration
Interventions: DEVICE: Immersive condition (CAVE)|DEVICE: Immersive condition (HMD)|DEVICE: Non Immersive condition (Screen alone)|DEVICE: Non Immersive condition (Screen with physical simulator)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Pacritinib Versus Best Available Therapy to Treat Patients With Myelofibrosis and Thrombocytopenia
Status: TERMINATED
Conditions: Primary Myelofibrosis|Post-polycythemia Vera Myelofibrosis|Post-essential Thrombocythemia Myelofibrosis
Interventions: DRUG: Pacritinib|DRUG: Best Available Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Plaque Test Comparing the Anti-psoriatic Effect of Marketed Products for Topical Use for Psoriasis Vulgaris
Status: COMPLETED
Conditions: Psoriasis Vulgaris
Interventions: DRUG: Daivobet® ointment|DRUG: Betnovat® ointment|DRUG: Diprosalic ointment|DRUG: Dermovat ointment|DRUG: Elocon ointment|DRUG: Daivobet® ointment vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose:
Clinical trial: Descriptive Analysis of Near Infrared Spectroscopy in Critically Ill and Injured Pediatric and Neonatal Patients
Status: TERMINATED
Conditions: Stroke|Diabetic Ketoacidosis|Increased Intracranial Pressures|Altered Mental Status
Interventions: DEVICE: NIRS
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Light Therapy in the Treatment of Leg Pain
Status: TERMINATED
Conditions: Tibial Fractures|Leg Injuries
Interventions: DEVICE: Monochromatic Near-Infrared Light Energy (MIRE)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Between Two Explorative Insulin Degludec Formulations and Between Two Explorative IDegAsp Formulations in Healthy Subjects
Status: COMPLETED
Conditions: Diabetes|Healthy
Interventions: DRUG: insulin degludec|DRUG: insulin degludec/insulin aspart
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Metoclopramide for Acute Upper GI Bleeding
Status: COMPLETED
Conditions: Acute Upper Gastrointestinal Bleeding|Effect of Drug
Interventions: DRUG: Metoclopramide|DRUG: Normal Saline 10 mL Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Double-blind, Vehicle-controlled Study of the Efficacy and Safety of SADBE in Subjects With Recurrent Herpes Labialis
Status: COMPLETED
Conditions: Herpes Labialis|Cold Sore
Interventions: DRUG: SADBE|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pravastatin Reduces Acute Phase Response of Zoledronic Acid
Status: UNKNOWN
Conditions: Postmenopausal Osteoporosis
Interventions: DRUG: Pravastatin Sodium 80 MG|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of PET/CT Scans With the Radioactive Tracer 89Zr-DFO-Daratumumab in People With Myeloma
Status: WITHDRAWN
Conditions: Multiple Myeloma
Interventions: DRUG: 89Zr-DFO-daratumumab|DIAGNOSTIC_TEST: PET/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Immunogenicity of Fluzone HD,A High Dose Influenza Vaccine, In Children With Cancer or HIV
Status: COMPLETED
Conditions: HIV|Cancer
Interventions: BIOLOGICAL: Fluzone High Dose Vaccine|BIOLOGICAL: Fluzone Standard Dose Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rituximab, Combination Chemotherapy, and 90-Yttrium Ibritumomab Tiuxetan for Patients With Stage I or II Non-Hodgkin's Lymphoma
Status: TERMINATED
Conditions: Contiguous Stage II Adult Diffuse Large Cell Lymphoma|Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue|Nodal Marginal Zone B-cell Lymphoma|Noncontiguous Stage II Adult Diffuse Large Cell Lymphoma|Splenic Marginal Zone Lymphoma|Stage I Adult Diffuse Large Cell Lymphoma|Testicular Lymphoma|Waldenström Macroglobulinemia
Interventions: BIOLOGICAL: rituximab|DRUG: prednisone|DRUG: cyclophosphamide|DRUG: doxorubicin|DRUG: vincristine|RADIATION: indium In 111 ibritumomab tiuxetan|RADIATION: radiation therapy|PROCEDURE: positron emission tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hydroxychloroquine and Temozolomide in Treating Patients With Metastatic or Unresectable Solid Tumors
Status: COMPLETED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: hydroxychloroquine|DRUG: temozolomide|GENETIC: TdT-mediated dUTP nick end labeling assay|GENETIC: western blotting|OTHER: electron microscopy|OTHER: high performance liquid chromatography|OTHER: immunoenzyme technique|OTHER: immunohistochemistry staining method|OTHER: laboratory biomarker analysis|OTHER: mass spectrometry|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SHARED Study (Saguenay Hospitals Anaphylaxis Rule for Early Discharge)
Status: TERMINATED
Conditions: Anaphylaxis|Biphasic Anaphylactic Reaction|Rebound Anaphylactic Reaction
Interventions: OTHER: Occurence of biphasic reaction following anaphylaxis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study in Healthy Males to Assess Distribution, Metabolism, and Excretion of Radio-labelled AZD9742 Administered as a 2-hour Infusion
Status: WITHDRAWN
Conditions: Healthy
Interventions: DRUG: [14C]-AZD9742
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Thoracolumber Oterfacial Plane Block for Spine Surgery
Status: UNKNOWN
Conditions: Spine Surgeries
Interventions: DRUG: Bupivacaine 0.5% injected in the thoraco-lumber inetrfacial plane block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Artesunate-Mefloquine Combination Therapy in Trat Province, Thailand
Status: COMPLETED
Conditions: Plasmodium Falciparum Malaria
Interventions: DRUG: Artesunate|DRUG: Artesunate|DRUG: Mefloquine|DRUG: Mefloquine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Topically Administered Oxybutynin Gel in Patients With Urge Incontinence
Status: COMPLETED
Conditions: Urge Urinary Incontinence|Urinary Frequency
Interventions: DRUG: Oxybutynin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Pharmacokinetic Study of DW6012 (FDC of Dapagliflozin and Sitagliptin) in Healthy Adult Volunteers
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: DW6012
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose Escalation Study of Teclistamab, a Humanized BCMA*CD3 Bispecific Antibody, in Participants With Relapsed or Refractory Multiple Myeloma
Status: RECRUITING
Conditions: Hematological Malignancies
Interventions: DRUG: Teclistamab (IV)|DRUG: Teclistamab(SC)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Early Clinical Trial to Evaluate VGN-R09b for Treatment of Aromatic L-amino Acid Decarboxylase (AADC) Deficiency.
Status: RECRUITING
Conditions: Aromatic L-amino Acid Decarboxylase (AADC) Deficiency
Interventions: DRUG: VGN-R09b
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: AG-120 in People With IDH1 Mutant Chondrosarcoma
Status: RECRUITING
Conditions: Chondrosarcoma|Chondrosarcoma, Grade 2|Chondrosarcoma, Grade 3|IDH1 Gene Mutation
Interventions: DRUG: AG-120
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Perioperative Pregabalin in Ureteroscopy: a Pilot
Status: COMPLETED
Conditions: Nephrolithiasis|Urolithiasis|Perioperative/Postoperative Complications|Pain, Postoperative|Pain, Acute|Anesthesia|Urologic Diseases|Anesthesia Morbidity
Interventions: DRUG: Pregabalin 300mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 3M™ Topical Tissue Adhesive Versus Commercially Available Tissue Adhesive for the Closure of Lacerations and Incisions
Status: NOT_YET_RECRUITING
Conditions: Trauma-related Wound|Surgical Incision|Surgical Wound|Laceration
Interventions: DEVICE: 3M Topical Tissue Adhesive|DEVICE: Histoacryl® Blue Topical Skin Adhesive
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prevalence of Serum-Vitamin D Abnormalities, Periodontitis and Anaemia in Patients With Melasma
Status: COMPLETED
Conditions: Melasma, Periodontitis, Vitamin D Abnormalities, Anaemia
Interventions: DIAGNOSTIC_TEST: vitamin D serum assay study and control groups|DIAGNOSTIC_TEST: Photometry|OTHER: Russels periodontal index
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Role of Vitamin C in Cardiac Vasoplegia After Cardiopulmonary Bypass
Status: UNKNOWN
Conditions: to Study the Effect of Vitamin C Administration on the Amount and the Time of Weaning of Noradrenaline Given Post-operatively to Patients After CPB
Interventions: DRUG: IV of vitamin C
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Randomized, 4-sequence, 2-period, Double-blind, Placebo Controlled Study With a DSM-IV-TR Diagnosis of Cocaine Abuse
Status: COMPLETED
Conditions: Opioid Dependence|Opioid Related Disorders|Cocaine Dependence
Interventions: DRUG: RBP-8000 100 mg|DRUG: Placebo|DRUG: Cocaine|DRUG: RBP-8000 200 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Prospective Comparison of Alcon LADARVision Wavefront-guided LASIK Enhancement and Conventional LASIK Enhancement for the Correction of Residual Refractive Errors Following LASIK Procedures
Status: COMPLETED
Conditions: Refractive Errors
Interventions: PROCEDURE: WAVEFRONT- GUIDED LASIK ENHANCEMENT|PROCEDURE: CONVENTIONAL LASIK ENHANCEMENT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study To Evaluate ASN002 In Subjects With Atopic Dermatitis
Status: COMPLETED
Conditions: Dermatitis, Atopic|Dermatitis Eczema|Dermatitis, Eczematous
Interventions: DRUG: ASN002|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fasting Study of Oxybutynin Chloride Extended-release Tablets 5 mg and Ditropan XL® Tablets 5 mg
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Oxybutynin Chloride Extended-release Tablets 5 mg|DRUG: Ditropan XL® Tablets 5 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Estrogen Therapy as Prevention in the Progression of Aneurysm (EPPA) Trial
Status: WITHDRAWN
Conditions: Cerebral Aneurysm|Menopause|Treatment
Interventions: DRUG: Estradiol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Oblimersen Plus Combination Chemotherapy and Dexrazoxane in Treating Children and Adolescents With Relapsed or Refractory Solid Tumors
Status: COMPLETED
Conditions: Cardiac Toxicity|Unspecified Childhood Solid Tumor, Protocol Specific
Interventions: BIOLOGICAL: oblimersen sodium|DRUG: dexrazoxane hydrochloride|DRUG: doxorubicin hydrochloride|DRUG: cyclophosphamide|BIOLOGICAL: filgrastim|OTHER: laboratory biomarker analysis|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Testing of a Co-adapted Group Programme for Parents/Carers of Children With Complex Neurodisability
Status: NOT_YET_RECRUITING
Conditions: Complex Neurodevelopmental Disorder|Cerebral Palsy
Interventions: BEHAVIORAL: "Encompass" group programme
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Hydrocortisone Versus Hydrocortisone Plus Fludrocortisone for the Treatment of Adrenal Insufficiency in Severe Sepsis
Status: WITHDRAWN
Conditions: Sepsis|Adrenal Insufficiency
Interventions: DRUG: Hydrocortisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Primary TKA Cruciate Retaining vs Cruciate Substituting With Rotating Platform Knee Prostheses
Status: TERMINATED
Conditions: Osteoarthritis|Arthritis, Rheumatoid|Avascular Necrosis of Bone|Post-traumatic Arthritis|Rheumatoid Arthritis
Interventions: DEVICE: Total Knee Replacement|DEVICE: Total knee replacement
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Non-surgical Periodontal Treatment in the Renal Function of Patients With Chronic Kidney Disease: RCT
Status: COMPLETED
Conditions: Chronic Kidney Disease|Periodontitis
Interventions: PROCEDURE: Full Mouth Non-Surgical Periodontal Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multi-channel Time-resolved Functional Near Infrared Spectroscopy for Prevention of Perioperative Brain Injury
Status: RECRUITING
Conditions: Stroke|Cerebral Oxygenation
Interventions: DEVICE: multichannel time-resolved (tr) functional near infrared spectroscopy (fNIRS) (tr-fNIRS)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Use of an Endoluminal-suturing Device for Endoscopic Gastric Reduction as an Aid for Class I Obesity, or Class II Obesity Without Comorbidity
Status: UNKNOWN
Conditions: Bariatric Surgery|Morbid Obesity
Interventions: PROCEDURE: Vertical gastric plication
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Enzastaurin in the Treatment of Persistent or Recurrent Ovarian or Primary Peritoneal Cancer
Status: COMPLETED
Conditions: Ovarian Cancer|Neoplasms|Carcinoma
Interventions: DRUG: enzastaurin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Osseointegration of THA Grafted by PolyNASS (ACTISURF-CERAFIT® ) Versus Non-grafted THA (CERAFIT®
Status: ACTIVE_NOT_RECRUITING
Conditions: Osteoarthritis, Hip
Interventions: DEVICE: Total Hip Arthroplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ADA Gene Transfer Into Hematopoietic Stem/Progenitor Cells for the Treatment of ADA-SCID
Status: COMPLETED
Conditions: Immunologic Deficiency Syndromes
Interventions: GENETIC: Gene Therapy|DRUG: Busulfan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low Impact Laparoscopic in Colorectal Resection - PAROS2
Status: RECRUITING
Conditions: Malignant or Benign Pathology
Interventions: PROCEDURE: Low pressure + microsurgical instruments|PROCEDURE: Low pressure + standard instruments
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Exploratory Clinical Trial of Safety and Efficacy of Sacral Nerve Stimulation in Patients With Ulcerative Colitis.
Status: RECRUITING
Conditions: Ulcerative Colitis
Interventions: DEVICE: G132 system, Beijing PINS Medical Co., China
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I and II Study Of Stereotactic Body Radiotherapy in Medically Unresectable Patients With Stage 1 NSCLC
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer
Interventions: PROCEDURE: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Psychological Treatment in Psychiatric Inpatient Care
Status: TERMINATED
Conditions: Compulsory Psychiatric Care Act|Psychosis|Acceptance & Commitment Therapy|Psychiatric Hospitalization|Psychiatric Disorder
Interventions: BEHAVIORAL: ACT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stereotactic Body Radiotherapy (SBRT) Versus Stereotactic Body Proton Therapy (SBPT)
Status: TERMINATED
Conditions: Non-small-cell Lung Cancer
Interventions: RADIATION: SBRT (stereotactic body radiotherapy)|RADIATION: SBPT (stereotactic body proton therapy)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Controlled Study of NGX-4010 for the Treatment of Postherpetic Neuralgia
Status: COMPLETED
Conditions: Herpes Zoster|Neuralgia|Pain|Peripheral Nervous System Diseases
Interventions: DRUG: Capsaicin Dermal Patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Using Probability of Community-Acquired Pneumonia to Tailor Antimicrobials Among Inpatients
Status: RECRUITING
Conditions: Pneumonia|Pneumonia, Viral|Pneumonia, Bacterial
Interventions: BEHAVIORAL: Electronic alert|BEHAVIORAL: Structured communication of test results
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Metformin in Kidney Disease
Status: COMPLETED
Conditions: Chronic Kidney Disease|Cardiovascular Disease|Metabolic Syndrome
Interventions: DRUG: metformin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Early Anatomical, Physiological, and Clinical Changes in Diabetic Macular Edema After Intravitreal Aflibercept Injection
Status: COMPLETED
Conditions: Diabetic Macular Edema|Diabetic Retinopathy|Clinically Significant Macular Edema
Interventions: DRUG: Aflibercept Injection [Eylea]
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Use of Brain Activity Monitoring for Prediction of Migraine Attacks
Status: UNKNOWN
Conditions: Migraine
Interventions: DEVICE: EEG monitoring (MindWave by NeuroSky)|DEVICE: EEG monitoring (EPOC by Emotiv)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Feasibility of the Radio-Frequency Microstimulator System to Improve Arm Function Following Traumatic Brain Injury
Status: TERMINATED
Conditions: Traumatic Brain Injury
Interventions: OTHER: Upper Extremity Therapy without stimulation|DEVICE: Upper Extremity Therapy with stimulation from the Radiofrequency Microstimulator (RFM) System (Alfred Mann Foundation, Santa Clarita, CA)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Amniotic Membrane for Dacryocystorhinostomy
Status: RECRUITING
Conditions: Nasolacrimal Duct Obstruction|Dacryocystorhinostomy
Interventions: PROCEDURE: Dacryocystorhinostomy and amniotic membrane|PROCEDURE: Conventional dacryocystorhinostomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Research on Optimizing the Use of Technology With Education
Status: ACTIVE_NOT_RECRUITING
Conditions: Type 1 Diabetes|Continuous Glucose Monitoring|Behavioral Intervention|Parent-Child Relations
Interventions: BEHAVIORAL: diabetes education and parent coaching support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Is Chiropractic Spinal Manipulative Therapy an Efficient Treatment Option in Cervicogenic Headache
Status: COMPLETED
Conditions: Cervicogenic Headache
Interventions: OTHER: Chiropractic|OTHER: Sham Chiropractic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PET Study to Determine the Relationship Between Plasma Concentrations and Muscarinic Type 1 Receptor (M1AChR) Occupancy of PIPE-307 in Healthy Volunteers
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DRUG: PIPE-307
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 3 Study of ThermoDox With Radiofrequency Ablation (RFA) in Treatment of Hepatocellular Carcinoma (HCC)
Status: COMPLETED
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: ThermoDox|DRUG: 5% Dextrose Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Dose-Ranging Study of the Safety and Efficacy of ADX415 in the Treatment of Essential Hypertension
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: ADX415|DRUG: ADX415|DRUG: ADX415|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ultrasound Guided Pericapsular Nerve Group Block Versus Ultrasound Guided Caudal Block for Postoperative Pain in Paediatric Hip Surgery
Status: RECRUITING
Conditions: Postoperative Pain in Paediatric Hip Surgery|PENG Block|Caudal Block
Interventions: PROCEDURE: ultrasound guided peng block in paediatric hip surgery|PROCEDURE: ultrasound guided caudal epidural block in paediatric hip surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of LAPS-Exendin on Body Weight in Obese Population
Status: COMPLETED
Conditions: Obesity
Interventions: BIOLOGICAL: HM11260C|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Tolerability, and Safety of Once-Daily Atomoxetine Hydrochloride Versus Placebo in Russian Children and Adolescents With Attention-Deficit/Hyperactivity Disorder
Status: COMPLETED
Conditions: Attention Deficit Disorder With Hyperactivity
Interventions: DRUG: atomoxetine|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Comparing Two Different Emotion Therapies for Autistic Youth and Young Adults
Status: RECRUITING
Conditions: Autism Spectrum Disorder
Interventions: BEHAVIORAL: The Emotion Awareness and Skills Enhancement Program|BEHAVIORAL: The Unified Protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Safety and Efficacy of Modafinil in Children and Adolescents With ADHD
Status: COMPLETED
Conditions: Attention Deficit/Hyperactivity Disorder|ADHD
Interventions: DRUG: Modafinil
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of the Hopeful Outdoor Parkinson Exercise (HOPE) Program on Improving Balance Performance in Parkinsonian Non-fallers and Single Fallers
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: BEHAVIORAL: an 8-week blended indoor-outdoor exercise program|BEHAVIORAL: an 8-week upper limb and hand exercise program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Role of TCM on ERAS of Rectal Cancer Patients
Status: UNKNOWN
Conditions: Rectal Cancer
Interventions: COMBINATION_PRODUCT: acupoint with TCM|COMBINATION_PRODUCT: acupoint with placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: JUPITER - Crestor 20mg Versus Placebo in Prevention of Cardiovascular (CV) Events
Status: TERMINATED
Conditions: Elevated High-sensitivity C-Reactive Protein (hsCRP)
Interventions: DRUG: Rosuvastatin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Efficacy of Intravitreal Aflibercept Injection in Improvement of Retinal Nonperfusion in Diabetic Retinopathy
Status: UNKNOWN
Conditions: Diabetic Retinopathy
Interventions: DRUG: Intravitreal Aflibercept injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Dietary Ingredients on Vascular Function
Status: COMPLETED
Conditions: Vascular Diseases|Impaired Glucose Tolerance
Interventions: DIETARY_SUPPLEMENT: A capsule containing both polyphenols and carotenoids|DIETARY_SUPPLEMENT: Placebo intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Open-label Dose Escalation Phase 1b Trial of a New Micellar Docetaxel Compound in Patients With mCRPC
Status: TERMINATED
Conditions: Metastatic Castration-resistant Prostate Cancer
Interventions: DRUG: Docetaxel micellar
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasound Guided Intra-sacroiliac Joint Injection: Methylprednisolone Versus Triamcinolone
Status: UNKNOWN
Conditions: Sacroiliac Joint Arthritis
Interventions: DRUG: sacroiliac joint injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Ultrasound-guided Erector Spinae Plane Block Versus Retrolaminar Block for Postoperative Analgesia in Thoracotomy
Status: COMPLETED
Conditions: Postoperative Analgesia|Retrolaminar Block|Ultrasound-guided Erector Spinae Plane Block|Thoracotomy
Interventions: PROCEDURE: Ultrasound-guided Erector Spinae Plane Block|PROCEDURE: Retrolaminar Block|PROCEDURE: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Co-Design and Pilot Testing of Peer-led Community Outreach to Improve Equity, Veteran-Centeredness and Uptake of Lung Cancer Screening
Status: NOT_YET_RECRUITING
Conditions: Lung Cancer
Interventions: OTHER: Veterans peer connect Program
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Abdominal Functional Electrical Stimulation to Improve Bowel Function in Spinal Cord Injury
Status: NOT_YET_RECRUITING
Conditions: Spinal Cord Injuries|Neurogenic Bowel
Interventions: BEHAVIORAL: Abdominal Functional Electrical Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acceptability and Performance of a Mobile Optical Biopsy Technology for Gastrointestinal Cancer Screening
Status: COMPLETED
Conditions: Suspected or Known Squamous Cell Neoplasia|Prior History of Squamous Cell Dysplasia and /or Neoplasia
Interventions: DRUG: Proflavine|DEVICE: Mobile, Augmented High Resolution Microendoscope
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER