pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Prospective Study Comparing Methods of Obtainment of Specimen After EUS-FNA in Patients With Peri-pancreatic Mass
Status: COMPLETED
Conditions: Pancreatic Neoplasm|Neoplasm of Intra-abdominal Lymph Nodes
Interventions: PROCEDURE: 1.EUS-FNA with or without suction|PROCEDURE: 2.Pushing the stylet or injecting air
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effect of Transcranial Direct Current Stimulation on Visual Attention - Single Sessions
Status: COMPLETED
Conditions: Healthy Aging|Cognitive Change|Cognitive Decline
Interventions: DEVICE: Transcranial direct current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Testing Olaparib and AZD6738 in IDH1 and IDH2 Mutant Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Malignant Solid Neoplasm|Refractory Cholangiocarcinoma|Refractory Malignant Solid Neoplasm
Interventions: PROCEDURE: Biopsy|PROCEDURE: Biospecimen Collection|PROCEDURE: Bone Marrow Aspiration|PROCEDURE: Bone Marrow Biopsy|DRUG: Ceralasertib|PROCEDURE: Computed Tomography|PROCEDURE: Magnetic Resonance Imaging|DRUG: Olaparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Recombinant Vaccine to Prevent ETEC Diarrhea
Status: COMPLETED
Conditions: Escherichia Coli Infection
Interventions: BIOLOGICAL: Recombinant fimbrial adhesin dscCfaE|BIOLOGICAL: Recombinant fimbrial adhesin dscCfaE|BIOLOGICAL: Recombinant fimbrial adhesin dscCfaE|BIOLOGICAL: Modified E. coli heat labile enterotoxin LTR192G
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy, Safety and Tolerability of PF-06687234 as Add-on Therapy to Infliximab in Active UC Subjects Not in Remission.
Status: TERMINATED
Conditions: Ulcerative Colitis
Interventions: DRUG: PF-06687234|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Voices for Food: Food Policy Councils, Food Security and Healthy Food Choices
Status: COMPLETED
Conditions: Food Security|Nutritive Value
Interventions: BEHAVIORAL: Coaching and Voices for Food Kit|BEHAVIORAL: Voices for Food Kit
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Chewing Gum After Cesarean Section on Gastrointestinal System Functions, Pain and Sleep Quality
Status: RECRUITING
Conditions: Mothers|Cesarean Section Complications
Interventions: OTHER: Gum chewing group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Exercise and Weight Loss for Improving Mobility in Older Adults Who Are Obese
Status: COMPLETED
Conditions: Cardiovascular Diseases|Heart Diseases|Metabolic Syndrome X|Obesity
Interventions: BEHAVIORAL: Exercise|BEHAVIORAL: Weight Loss|BEHAVIORAL: Health Education Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Imatinib Mesylate in Treating Patients With Liver Metastasis From a Gastrointestinal Stromal Tumor
Status: COMPLETED
Conditions: Gastrointestinal Stromal Tumor|Metastatic Cancer
Interventions: DRUG: imatinib mesylate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cranberry Extract and Urinary Infection Prevention: a Clinical Trial
Status: UNKNOWN
Conditions: Urinary Tract Infections
Interventions: DIETARY_SUPPLEMENT: Cranberry extract
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study to Evaluate the Safety and Efficacy of a Proprietary "Joint Health" Dietary Supplement in Subjects With Joint and Connective Tissue Pain
Status: COMPLETED
Conditions: Joint Pain
Interventions: DIETARY_SUPPLEMENT: Joint Health Product|DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: Glucosamine / Chondroitin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: THERMOCOOL® SMARTTOUCH™ Catheter for the Treatment of Symptomatic Paroxysmal Atrial Fibrillation CONTINUED ACCESS
Status: COMPLETED
Conditions: Drug Refractory Symptomatic Paroxysmal Atrial Fibrillation
Interventions: DEVICE: THERMOCOOL® SMARTTOUCH™ Catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pancreatic Cancer Adaptive Neoadjuvant Chemotherapy Trial
Status: RECRUITING
Conditions: Pancreatic Cancer
Interventions: DRUG: First-line Chemotherapy|DRUG: Second-line Chemotherapy|RADIATION: Chemoradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neuromodulation of the Autonomic Nervous System in Athletes
Status: RECRUITING
Conditions: Efficacy, Self|Fatigue; Muscle, Heart|Fatigue, Mental|Fatigue; Combat
Interventions: DEVICE: tVNS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Supporting Patient Activation in Transition to Home Intervention
Status: COMPLETED
Conditions: Medication Adherence|Self-care|Heart Failure|Chronic Obstructive Pulmonary Disease
Interventions: BEHAVIORAL: Motivational Interviewing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Optimal Cardiopulmonary Bypass and Anticoagulation Management Strategies in Obese Patients Undergoing Cardiac Surgery
Status: RECRUITING
Conditions: Cardiopulmonary Bypass|Obesity
Interventions: DRUG: Heparin|PROCEDURE: cardiopulmonary bypass pump flow rate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of CyclaPlex Implant for Correction of First Inter Metatarsal Angle in Subjects Suffering From Hallux Valgus Deformity
Status: UNKNOWN
Conditions: Hallux Valgus
Interventions: DEVICE: CyclaPlex Implant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treprostinil Sodium Inhalation for Patients At High Risk for ARDS
Status: TERMINATED
Conditions: Respiratory Distress Syndrome, Adult
Interventions: DRUG: Treprostinil Inhalation Solution|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Neoadjuvant Ifosfamide, Doxorubicin, Gemcitabine, and Cisplatin in Treating Patients Who Are Undergoing Radical Cystectomy for Locally Advanced Carcinoma (Cancer) of the Urothelium
Status: COMPLETED
Conditions: Bladder Cancer|Transitional Cell Cancer of the Renal Pelvis and Ureter|Urethral Cancer
Interventions: BIOLOGICAL: filgrastim|DRUG: cisplatin|DRUG: doxorubicin hydrochloride|DRUG: gemcitabine hydrochloride|DRUG: ifosfamide|PROCEDURE: conventional surgery|PROCEDURE: neoadjuvant therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Inflammatory Markers in Patients With and Without Depression With Chronic Periodontitis
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Periodontitis|Depression
Interventions: PROCEDURE: Periodontal Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Trial to Evaluate Safety, Tolerability, Efficacy of PerioSept® as Adjunct to SRP in Subjects With Periodontitis
Status: COMPLETED
Conditions: Periodontitis
Interventions: DRUG: PerioSept(r)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Alendronate on Bone in People With Chronic Spinal Cord Injury (SCI) Previously Treated With Teriparatide
Status: COMPLETED
Conditions: Spinal Cord Injury|Bone Loss|Osteoporosis
Interventions: DRUG: Alendronate|DIETARY_SUPPLEMENT: Calcium|DIETARY_SUPPLEMENT: Vitamin D
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Behavioral Treatment of Menopausal Insomnia; Sleep and Daytime Outcomes
Status: COMPLETED
Conditions: Menopause
Interventions: BEHAVIORAL: Cognitive Behavioral Therapy for Insomnia|BEHAVIORAL: Sleep Education|BEHAVIORAL: Sleep Restriction Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Traditional Chinese Medicine or Low-dose Dexamethasone in COVID-19 Pneumonia
Status: RECRUITING
Conditions: COVID-19 Pneumonia
Interventions: OTHER: conventional western medicine treatment|DRUG: Dexamethasone oral tablet|OTHER: Traditional Chinese medicine decoction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: N-methyl-D-aspartic Acid (NMDA) and Cognitive Remediation in Schizophrenia
Status: UNKNOWN
Conditions: Schizophrenia|Schizoaffective Disorder
Interventions: DRUG: D-serine|DRUG: placebo|BEHAVIORAL: Sensory Based remediation paradigm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Retrovir and Epivir Alone or in Combination With 141W94 in HIV-Infected Patients
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Amprenavir|DRUG: Lamivudine|DRUG: Zidovudine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: Flourish™ Pediatric Esophageal Atresia
Status: COMPLETED
Conditions: Esophageal Atresia|Digestive System Abnormalities|Esophageal Disorders Congenital
Interventions: DEVICE: Flourish Pediatric Esphogeal Atresia device
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Placebo in Acupuncture
Status: UNKNOWN
Conditions: Nausea|Vomiting
Interventions: DRUG: Acupuncture|DEVICE: Sham acupuncture|DEVICE: Laser acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: Evaluation of Efficacy of Lycium Barbarum Polysaccharide in People With Subthreshold Depression
Status: UNKNOWN
Conditions: Subthreshold Depression|Depressive Symptoms|Anxious Symptoms
Interventions: DIETARY_SUPPLEMENT: Lycium barbarum polysaccharide|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Systematic Aerobics and Intelligent Monitoring System in Executive Skill Training for School-aged Children With ADHD
Status: RECRUITING
Conditions: ADHD
Interventions: PROCEDURE: systematic aerobic exercise and intelligent monitoring system in executive skill training|PROCEDURE: executive skill training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Standard Oral Colonoscopic Preparations With or Without Neostigmine Compared to Pulse-Irrigation Colonic Lavage
Status: COMPLETED
Conditions: Spinal Cord Injury
Interventions: DRUG: Neostigmine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Study to Investigate Safety, Absorption, Elimination, and Drug Effect of BAY2327949 in Participants With Different Renal Function Status
Status: COMPLETED
Conditions: Pharmacokinetics
Interventions: DRUG: BAY2327949
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Comparison of Lymph Drainage and Connective Tissue Massage in Fibromyalgia Patients
Status: COMPLETED
Conditions: Fibromyalgia
Interventions: OTHER: Manual Lymph Drainage Therapy and Connective Tissue Massage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics of Enteral Omeprazole Suspension in Patients With Cerebral Palsy and Mental Retardation
Status: COMPLETED
Conditions: Gastreoesophageal Reflux Disease
Interventions: DRUG: Administration of omeprazole suspension|DRUG: omeprazole administered as a multi-unit-pellet system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Capecitabine and Bevacizumab With or Without Atezolizumab in Treating Patients With Refractory Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Metastatic Colorectal Carcinoma|Recurrent Colorectal Carcinoma|Refractory Colorectal Carcinoma|Stage IV Colorectal Cancer AJCC v7|Stage IVA Colorectal Cancer AJCC v7|Stage IVB Colorectal Cancer AJCC v7
Interventions: DRUG: Atezolizumab|BIOLOGICAL: Bevacizumab|DRUG: Capecitabine|OTHER: Laboratory Biomarker Analysis|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Orphenadrine' in the Treatment of Muscle Cramps in Patients With Cirrhosis
Status: RECRUITING
Conditions: Liver Cirrhosis|Muscle Cramps
Interventions: DRUG: orphenadrine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Therapeutic Ultrasound in the Treatment of Migraine
Status: COMPLETED
Conditions: Migraine|Ultrasound
Interventions: DEVICE: therapeutic ultrasound|DEVICE: placebo ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating a Patient-Centered Tool to Help Medicare Beneficiaries Choose Prescription Drug Plans
Status: COMPLETED
Conditions: Prescription Drug Insurance Decision Making
Interventions: BEHAVIORAL: Expert Recommendation|BEHAVIORAL: Individual Analysis|BEHAVIORAL: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Ketamine for Acute Suicidal Ideation in the Emergency Department: Randomized Controlled Trial
Status: UNKNOWN
Conditions: Suicide
Interventions: DRUG: Ketamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Opioid System Cerebral Activity in Endurance Sportswomen - Addiction or Denutrition ? [11C]Diprenorphine PET Study
Status: COMPLETED
Conditions: Sports Nutritional Sciences
Interventions: OTHER: [11C]diprenorphine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Bilateral Rhomboid Intercostal Block for Perioperative Analgesia in Patients Undergoing Bilateral Reduction Mammoplasty
Status: RECRUITING
Conditions: Analgesia
Interventions: PROCEDURE: general anesthesia|PROCEDURE: Erector spinae plane block|PROCEDURE: a rhomboid intercostal nerve block|DRUG: Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Ripple Mapping in Atrial Tachycardia Ablation
Status: COMPLETED
Conditions: Atrial Tachycardia
Interventions: DEVICE: Ripple Mapping guided AT ablation|DEVICE: Local activation Time Mapping AT Ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, Pharmacokinetics and Food Effects of Oral EC5026 in Healthy Subjects
Status: COMPLETED
Conditions: Healthy Adults
Interventions: DRUG: EC5026 oral tablet|OTHER: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Serum Sample Collection to Determine Analytical Performance Characteristics of the ADVIA Centaur PAPPA and BhCG Assays
Status: COMPLETED
Conditions: Trisomy 21 in Fetus|Trisomy 18 in Fetus|Trisomy 13 in Fetus
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Different Deflation Methods on Coughing Response and Hemodynamics During Extubation
Status: RECRUITING
Conditions: Deflating Method
Interventions: BEHAVIORAL: Tracheal tube cuffs differ in deflation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Vertebral Derotation on Pulmonary Functions
Status: RECRUITING
Conditions: Adolescent Idiopathic Scoliosis|Scoliosis Idiopathic
Interventions: PROCEDURE: vertebral derotation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Clinical Information and Biospecimen Collection From Patients With Recurrent or Stage IV Breast Cancer
Status: SUSPENDED
Conditions: Anatomic Stage IV Breast Cancer AJCC v8|Invasive Breast Carcinoma|Metastatic Breast Carcinoma|Peritoneal Effusion|Recurrent Breast Carcinoma
Interventions: PROCEDURE: Biospecimen Collection|OTHER: Medical Chart Review
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Evaluate the Safety, Reactogenicity and Immunogenicity of Prophylactic Hepatitis B Vaccine
Status: COMPLETED
Conditions: Vaccine-Preventable Diseases|Hepatitis B
Interventions: BIOLOGICAL: CVI-HBV-002
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Nasobiliary Drain Assisted EUS-guided Gastroenterostomies in Unresectable Malignant Gastric Outlet Obstruction
Status: COMPLETED
Conditions: Gastric Outlet Obstruction|Gastric Cancer|Pancreatic Cancer
Interventions: DEVICE: EUS-guided gastroenterostomy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phase 2 Reduction of Dietary Mycotoxin Exposure by ACCS100"
Status: COMPLETED
Conditions: Dietary Carcinogenesis
Interventions: DRUG: ACCS100|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Mapping and Pacing of the His Bundle for Heart Failure Patients With Left Bundle Branch Block
Status: COMPLETED
Conditions: Heart Failure|Left Bundle-Branch Block
Interventions: PROCEDURE: Mapping and Pacing the His Bundle|PROCEDURE: Placing a guidewire in Coronary sinus for measurement of Q-LV during His Bundle pacing or, if needed, for LV pacing
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity of a Recombinant Human Papillomavirus Nonavalent (Types 6,11,16,18,31,33,45,52,58)Vaccine(E.Coli) Versus Gardasil®9 in Healthy Females 18-26 Years of Age
Status: COMPLETED
Conditions: Cervical Cancer|Condylomata Acuminata
Interventions: BIOLOGICAL: Recombinant Human Papillomavirus Nonavalent (Types 6,11,16,18,31,33,45,52,58 )Vaccine(E.Coli)|BIOLOGICAL: Gardasil®9
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Study on Optimal Oxygen Concentration During Pulmonary Rehabilitation
Status: RECRUITING
Conditions: High-flow Nasal Cannula|Exercise Capacity|Chronic Respiratory Failure|Optimal SpO2 Value
Interventions: OTHER: High-flow nasal cannula|OTHER: Low SpO2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Postoperative Neurocognitive Dysfunction: Is There Any Place for Emergency Agitation: A Prospective Cohort Trial
Status: COMPLETED
Conditions: Emergence Delirium|Emergence Agitation|Postoperative Delirium
Interventions: DIAGNOSTIC_TEST: RASS|DIAGNOSTIC_TEST: CAM-ICU
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phase III Efficacy and Safety Clinical Study of UF-021 for Treatment of Retinitis Pigmentosa
Status: TERMINATED
Conditions: Retinitis Pigmentosa
Interventions: DRUG: UF-021|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Robotic Therapy and Brain Stimulation in the Early Phase After Stroke
Status: ACTIVE_NOT_RECRUITING
Conditions: Stroke
Interventions: DEVICE: Robotic Therapy|DEVICE: Active stimulation|DEVICE: Sham stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Mindfulness Based Childbirth and Parenting Education - RCT of Effects on Parent and Child Health
Status: COMPLETED
Conditions: Parent-Child Relations|Depression, Postpartum|Stress, Physiological|Stress, Psychological
Interventions: BEHAVIORAL: MBCP|BEHAVIORAL: Psychoprophylaxis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparing the Safety, Effectiveness, and Tolerability of Three Anti-HIV Drug Regimens for Treatment-Naive Patients
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Lopinavir/ritonavir|DRUG: Efavirenz|DRUG: Stavudine|DRUG: Zidovudine|DRUG: Lamivudine|DRUG: Tenofovir disoproxil fumarate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Addition of Lidocaine to Levobupivacaine Reduces Intrathecal Block Duration
Status: COMPLETED
Conditions: Benign Prostate Hyperplasia
Interventions: DRUG: Levobupivacaine lidocaine spinal anesthesia|DRUG: levobupivacaine Spinal anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Remimazolam Tosilate for Sedation in the Upper Gastrointestinal Endoscopy
Status: COMPLETED
Conditions: Sedation in the Upper Gastrointestinal Endoscopy
Interventions: DRUG: Remimazolam Tosilate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hypofractionated vs Standard Radiotherapy in Breast Cancer With an Indication for Regional Lymph Node Irradiation About Lymphedema Occurrence
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer Female
Interventions: RADIATION: HYPOFRACTIONATED|RADIATION: NORMOFRACTIONATED
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A HR20031 BE Study on Healthy Subjects
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: ARM A|DRUG: ARM B|DRUG: ARM C|DRUG: ARM D|DRUG: ARM E|DRUG: ARM F
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Efficacy and Safety of VX-864 in Participants With the PiZZ Genotype
Status: ACTIVE_NOT_RECRUITING
Conditions: Alpha-1 Antitrypsin Deficiency
Interventions: DRUG: VX-864
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Adapted Brazilian Cardioprotective Diet, Phytosterols and Krill Oil in Familial Hypercholesterolemia (DICA-FH)
Status: NOT_YET_RECRUITING
Conditions: Familial Hypercholesterolemia
Interventions: OTHER: Placebo phytosterol|OTHER: Placebo krill oil|DIETARY_SUPPLEMENT: Phytosterol|DIETARY_SUPPLEMENT: Krill oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Pharmacokinetics and Safety of Loncastuximab Tesirine in Participants With Relapsed or Refractory Diffuse Large B-cell Lymphoma or High-grade B-cell Lymphoma With Hepatic Impairment (LOTIS-10)
Status: RECRUITING
Conditions: Diffuse Large B-Cell Lymphoma|High-grade B-cell Lymphoma
Interventions: DRUG: Loncastuximab Tesirine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Treatment of Elderly Patients (>65 Years) With Acute Lymphoblastic Leukemia
Status: COMPLETED
Conditions: Adult Acute Lymphocytic Leukemia
Interventions: DRUG: Adriamycin|DRUG: Cyclophosphamide|DRUG: Cytarabine|DRUG: Dexamethasone|DRUG: Idarubicin|DRUG: Ifosfamide|DRUG: Methotrexate|DRUG: Mercaptopurine|DRUG: VM26|DRUG: Vincristine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of High-Dose Trivalent Inactivated Influenza Vaccine in Adults 50 to 64 Years of Age
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: High-Dose Trivalent Inactivated Influenza Vaccine|BIOLOGICAL: Trivalent Inactivated Influenza Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Trial to Assess Efficacy, Safety, Pharmacokinetics of Octreotide Subcutaneous Injection in Patients With Gastroentero-pancreatic Neuroendocrine Tumor (GEP-NET)
Status: RECRUITING
Conditions: Gastrointestinal Neuroendocrine Pancreatic Tumor
Interventions: DRUG: SYHX2008 injection|DRUG: Sandostatin LAR@
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Camrelizumab Plus Apatinib in Patients With High-risk Gestational Trophoblastic Neoplasia
Status: UNKNOWN
Conditions: Gestational Trophoblastic Neoplasia
Interventions: DRUG: Camrelizumab plus apatinib CohortA|DRUG: Camrelizumab plus apatinib Cohort B
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cardiovascular Mechanisms of Exercise Intolerance in Diabetes and the Role of Sex
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus|Healthy|Overweight|Cardiovascular Risk Factor
Interventions: OTHER: Cardiovascular exercise training
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Study of Targeting ROS1 in Combination With Endocrine Therapy in Invasive Lobular Carcinoma of the Breast (ROSALINE)
Status: ACTIVE_NOT_RECRUITING
Conditions: Invasive Lobular Breast Carcinoma|ER+ Breast Cancer|HER2-negative Breast Cancer
Interventions: DRUG: Entrectinib|DRUG: Letrozole|DRUG: Goserelin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Magnesium and Alpha Lipoic Acid Supplementation in Reducing Premature Uterine Contractions
Status: COMPLETED
Conditions: Pregnancy
Interventions: DIETARY_SUPPLEMENT: Magnesium plus alpha-lipoic acid|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose:
Clinical trial: Pragmatic Randomised Trial of the ESC 0/1 Versus 0/3 Hour Troponin Pathway
Status: RECRUITING
Conditions: Acute Coronary Syndrome|Troponin|Chest Pain|Point-of-care Systems
Interventions: DIAGNOSTIC_TEST: ESC 0/1 hour troponin pathway
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy of Jianpi Qushi Huatan Decoction in the Treatment of Polycystic Ovary Syndrome
Status: RECRUITING
Conditions: Polycystic Ovary Syndrome
Interventions: DRUG: Jianpi Qushi Huatan Decoction|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of mDCF in Combination or Not With Atezolizumab in Advanced Squamous Cell Anal Carcinoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Anal Cancer
Interventions: DRUG: MPDL3280A|DRUG: mDCF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Probiotics on GBS Colonization Status During Pregnancy: A Pilot Randomized Controlled Trial
Status: COMPLETED
Conditions: Group B Streptococcal Infection
Interventions: DRUG: Probiotic|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Effect of Juvederm Volift With Lidocaine on Aging Hands in Participants Age 35 and Older
Status: COMPLETED
Conditions: Skin Depressions|Skin Elasticity|Skin Laxity
Interventions: DEVICE: Juvéderm® VOLIFT with Lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Inflammation, NK Cells, Antisense Protein and Exosomes, and Correlation With Immune Response During HIV Infection
Status: UNKNOWN
Conditions: HIV Infections
Interventions: BIOLOGICAL: 20 ml blood test
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of Postoperative Pain After Single Visit Retreatment of Symptomatic and Asymptomatic Teeth
Status: COMPLETED
Conditions: Post-operative Pain|Retreatment|Symptomatic Periapical Periodontitis|Endodontic Disease|Asymptomatic Periapical Periodontitis
Interventions: PROCEDURE: Endodontic Retreatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of UB-921 in Healthy Volunteers
Status: COMPLETED
Conditions: Breast Neoplasm
Interventions: BIOLOGICAL: UB-921|BIOLOGICAL: Herceptin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study on Improved Dynamic Myocardial Perfusion With Less Effective Radiation Dose in CT (SIMPLE CT)
Status: COMPLETED
Conditions: Myocardial Ischemia
Interventions: PROCEDURE: Myocardial CT perfusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation the Pharmacokinetics, Safety, Tolerability of BCD-021 in Patients With Neovascular Age-related Macular Degeneration
Status: WITHDRAWN
Conditions: Neovascular Age-related Macular Degeneration
Interventions: DRUG: Bevacizumab (BCD-021)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: The Feasibility of Cognitive Process Therapy in Earthquake-affected Population With Mental Health Problems in Türkiye
Status: NOT_YET_RECRUITING
Conditions: Post Traumatic Stress Disorder|Depressive Symptoms|Well-Being, Psychological|Anxiety Disorders and Symptoms
Interventions: OTHER: Cognitive Processing Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lacosamide Versus Propranolol in Migraine
Status: COMPLETED
Conditions: Migraine Disorders
Interventions: DRUG: Lacosamide tablet|DRUG: Propranolol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Organ-Sparing Marrow-Targeted Irradiation Before Stem Cell Transplant in Treating Patients With High-Risk Hematologic Malignancies
Status: COMPLETED
Conditions: Adult Acute Lymphoblastic Leukemia in Remission|Adult Acute Myeloid Leukemia in Remission|Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities|Adult Acute Myeloid Leukemia With Del(5q)|Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)|Adult Acute Myeloid Leukemia With t(15;17)(q22;q12)|Adult Acute Myeloid Leukemia With t(16;16)(p13;q22)|Adult Acute Myeloid Leukemia With t(8;21)(q22;q22)|de Novo Myelodysplastic Syndromes|Previously Treated Myelodysplastic Syndromes|Recurrent Adult Acute Lymphoblastic Leukemia|Recurrent Adult Acute Myeloid Leukemia|Secondary Myelodysplastic Syndromes|Untreated Adult Acute Lymphoblastic Leukemia|Untreated Adult Acute Myeloid Leukemia
Interventions: RADIATION: radiation therapy|DRUG: cyclophosphamide|BIOLOGICAL: anti-thymocyte globulin|DRUG: tacrolimus|DRUG: methotrexate|PROCEDURE: allogeneic bone marrow transplantation|PROCEDURE: allogeneic hematopoietic stem cell transplantation|PROCEDURE: peripheral blood stem cell transplantation|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Telephone-Based Support Programs for People With Epilepsy
Status: RECRUITING
Conditions: Epilepsy
Interventions: BEHAVIORAL: UPLIFT (Using Practice and Learning to Increase Favorable Thoughts)|BEHAVIORAL: BOOST (Bringing Out Our Strength Together)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Improving Medication Prescribing-Related Outcomes for Vulnerable Elderly In Transitions
Status: RECRUITING
Conditions: Patient Discharge|Drug-Related Side Effects and Adverse Reactions|Aged|Health Care Costs
Interventions: OTHER: Medication Coordinated care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Influence of the Shoulder Position on the Catheter Tip Location During Infraclavicular Subclavian Approach
Status: COMPLETED
Conditions: Catheter Tip Location
Interventions: PROCEDURE: neutral shoulder position|PROCEDURE: lowered shoulder position
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Probiotics in Reducing Infections and Allergies in Young Children Starting Daycare
Status: COMPLETED
Conditions: Days Absent From Daycare|Respiratory Tract Infections|Gastrointestinal Infections|Allergy
Interventions: DIETARY_SUPPLEMENT: Probiotic (2 * 10^9 cfu/day)|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: This Prospective Study Has 2 Objectives: First, to Assess the Post-obturation Pain Utilizing Bioceramic Sealer and One Cone Technique. Second, to Compare the Intensity of Post-obturation Pain Following Unintentional Sealer Extrusion
Status: COMPLETED
Conditions: Pain, Postoperative|Endodontic Overfill
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Maintenance Plasma Exchange for Neuromyelitis Optica
Status: COMPLETED
Conditions: Neuromyelitis Optica|Neuromyelitis Optica Spectrum Disorder|Recurrent Idiopathic Longitudinally Extensive Transverse Myelitis
Interventions: PROCEDURE: Plasma exchange (PLEX)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: PEA in Functional Dyspepsia
Status: RECRUITING
Conditions: Dyspepsia and Other Specified Disorders of Function of Stomach
Interventions: DIETARY_SUPPLEMENT: Palmitoylethanolamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CPI-613 in Treating Patients With Locally Advanced or Metastatic Pancreatic Cancer
Status: COMPLETED
Conditions: Acinar Cell Adenocarcinoma of the Pancreas|Duct Cell Adenocarcinoma of the Pancreas|Recurrent Pancreatic Cancer|Stage III Pancreatic Cancer|Stage IV Pancreatic Cancer
Interventions: DRUG: 6,8-bis(benzylthio)octanoic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nab-paclitaxel Combined With S-1 as Adjuvant Chemotherapy for Stage Ⅲ Gastric Cancer
Status: RECRUITING
Conditions: Stomach Cancer
Interventions: DRUG: nab paclitaxel|DRUG: Tegafur|DRUG: Oxaliplatin|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study On The Relation Among Prescription, Syndrome and Disease of Turbid Phlegm and Blood Stasis for Coronary Heart Disease
Status: UNKNOWN
Conditions: Coronary Heart Disease
Interventions: DRUG: Danlou Tablets|DRUG: Tongmai Yangxin Pills
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Diclofenac Potassium Versus Prednisolone on Post-endodontic Pain and Pulpal IL-8 Expression
Status: UNKNOWN
Conditions: Symptomatic Irreversible Pulpitis
Interventions: DRUG: Prednisolone 30 mg|DRUG: Diclofenac Potassium 50mg Tab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neural Mechanisms of Meditation for Opioid-Treated Chronic Low Back Pain
Status: RECRUITING
Conditions: Low Back Pain|Opioid Use
Interventions: BEHAVIORAL: Meditation|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Toric Multifocal Contact Lens Manufactured in Etafilcon Material in a Low ADD Hyperopic Population
Status: COMPLETED
Conditions: Visual Acuity
Interventions: DEVICE: Toric Multifocal etafilcon A with PVP
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tongue Exercises and Reflux Therapy for Upper Airway Resistance Syndrome
Status: WITHDRAWN
Conditions: Obstructive Sleep Apnea|Upper Airway Resistance Syndrome|Gastroesophageal Reflux
Interventions: DRUG: omeprazole|BEHAVIORAL: Tongue exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Safety and Tolerability Study of Subcutaneous C.E.R.A. in Pre-Dialysis Participants With Chronic Renal Anemia
Status: TERMINATED
Conditions: Anemia
Interventions: DRUG: Methoxy polyethylene glycol-epoetin beta (C.E.R.A.)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Angiotensin-Neprilysin Inhibition in Hemodialysis Initiation
Status: RECRUITING
Conditions: Hemodialysis
Interventions: DRUG: Sacubitril-valsartan|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Software Treatments for Actively Reducing Severity of Cognitive Deficits in MDD (STARS-MDD)
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DEVICE: HOLD: Videogame
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II Study of RT-PEPC in Relapsed Mantle Cell Lymphoma
Status: COMPLETED
Conditions: Non-Hodgkin's Lymphoma
Interventions: DRUG: PEPC|DRUG: Thalidomide|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Safety, Tolerability and Efficacy of Saroglitazar Mg in Patients With Primary Biliary Cholangitis
Status: COMPLETED
Conditions: Primary Biliary Cirrhosis
Interventions: DRUG: Saroglitazar magnesium 2 mg|DRUG: Saroglitazar magnesium 4 mg|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Double-Blind, Randomized, Placebo-Controlled Study of Topical VDO for the Treatment of Herpes Simplex Labialis
Status: COMPLETED
Conditions: Herpes Labialis
Interventions: DRUG: VDO gel|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of the Sore Throat Lozenges to Treat Acute Sore Throats
Status: COMPLETED
Conditions: Tonsillopharyngitis|Respiratory Tract Infection Viral
Interventions: DRUG: A. Vogels Sore Throat lozenges
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized Trial of Base-in Prism Reading Glasses Convergence Insufficiency in Children
Status: COMPLETED
Conditions: Convergence Insufficiency
Interventions: PROCEDURE: Base-in prism glasses for reading|PROCEDURE: Placebo reading glasses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Post-operative Dental Pain Study Comparing Analgesic Efficacy
Status: COMPLETED
Conditions: Post-surgical Dental Pain
Interventions: DRUG: Paracetamol 1000 mg|DRUG: Paracetamol 500 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Metformin Hydrochloride and Doxycycline in Treating Patients With Head and Neck Squamous Cell Carcinoma That Can Be Removed by Surgery
Status: ACTIVE_NOT_RECRUITING
Conditions: Larynx|LIP|Oral Cavity|Pharynx
Interventions: DRUG: Metformin Hydrochloride|DRUG: Doxycycline|DRUG: Metformin +Doxycycline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Antitumor Activity of ADCT-901 in Participants With Selected Advanced Solid Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Solid Tumors
Interventions: DRUG: ADCT-901
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Efficacy of SNA-120 for Treatment of Pruritus and Psoriasis in Subjects Treated With Calcipotriene
Status: COMPLETED
Conditions: Pruritus|Psoriasis
Interventions: DRUG: SNA-120|DRUG: Placebo|DRUG: Calcipotriene
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study of the Efficacy of Natalizumab on Reducing Disability Progression in Participants With Secondary Progressive Multiple Sclerosis
Status: TERMINATED
Conditions: Secondary Progressive Multiple Sclerosis
Interventions: DRUG: natalizumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect Of Strengthening Hip Rotators And Ankle Muscles On Knee Osteoarthritis
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: OTHER: therapeutic exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Length and Quality of Prostate Biopsies Taken by a New Biopsy Needle
Status: RECRUITING
Conditions: Prostate Cancer (Diagnosis)
Interventions: DEVICE: Novel needle (18 G, 25 cm with 19 mm sample notch) in a new actuator.|DEVICE: Standard Tru Cut biopsy needle (Argon 18G, 25 cm biopsy needle with a 19 mm sample notch) in a standard actuator (Möller Medical Blue RBG-1000-10-1000)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Assessment Of Dose-Dependent Immunomodulatory Effect Of Alveofact With or Without Steroisd In Neonatal RDS
Status: RECRUITING
Conditions: Neonatal Respiratory Distress Syndrome|Inflammatory Response|Premature Lungs|Neutrophil Extracellular Trap Formation|Preterm Birth
Interventions: DRUG: Alveofact|DRUG: Budesonide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT