pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Bupropion For Reducing High-Risk Behaviors in Depressed Men Who Have Sex With Men (MSM)
Status: COMPLETED
Conditions: HIV Infections|Depression
Interventions: DRUG: Bupropion|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: PKU Carriers Trial (Pilot Study): Impact on Cognition, Mental Health, Blood Pressure and Metabolism
Status: RECRUITING
Conditions: Autosomal Recessive Disorder (Genetic Carriers of PKU)
Interventions: DIETARY_SUPPLEMENT: L-Phenylalanine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Volar Locked Plating vs Bridging External Fixation in Distal Radius Fracture
Status: COMPLETED
Conditions: Distal Radius Fracture
Interventions: DEVICE: Volar locked plating|DEVICE: Hoffman external fixator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of ARO-APOC3 (Plozasiran) in Adults With Familial Chylomicronemia Syndrome (FCS)
Status: ACTIVE_NOT_RECRUITING
Conditions: Familial Chylomicronemia
Interventions: DRUG: Plozasiran|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Plasticity-based Adaptive Cognitive Remediation for Alzheimer Disease
Status: COMPLETED
Conditions: Older Adults, Aging Brain
Interventions: BEHAVIORAL: Computerized Plasticity-based Software|BEHAVIORAL: Commercially available Video Game
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Improvement of Lung and Thoracic Compliance in ARDS Patients in Prone Position by Using Inflatable Air Bag
Status: UNKNOWN
Conditions: ARDS|Prone Position|Mechanical Ventilation|Airbag
Interventions: OTHER: prone position with airbags|OTHER: prone position without airbags
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Value of an Intervention to Enhance Adherence in Glaucoma Patients
Status: COMPLETED
Conditions: Glaucoma
Interventions: DEVICE: TDA adherence monitor for travoprost therapy|DEVICE: TDA and travoprost monotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: HEPMET-1: Evaluate the Feasibility, Mental Sideeffects and the Efficacy of Hepatitis C Treatment in a MMT Group.
Status: COMPLETED
Conditions: Opiate Dependence|Hepatitis
Interventions: DRUG: Ribavirin|DRUG: Pegylated Interferon
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transcranial Alternating Current Stimulation in Back Pain- Pilot Sudy
Status: COMPLETED
Conditions: Chronic Low Back Pain
Interventions: DEVICE: XCSITE100 Stimulator Sham|DEVICE: XCSITE100 Stimulator tACS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Immune Monitoring and CNI Withdrawal in Low Risk Recipients of Kidney Transplantation
Status: TERMINATED
Conditions: Kidney Transplant Recipients
Interventions: DRUG: Tacrolimus (CNI) Withdrawal|DRUG: Standard Immunosuppressive Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of VR and Mural Curtain During Colonoscopy
Status: UNKNOWN
Conditions: Misadventure During Endoscopic Examination
Interventions: DEVICE: Virtual Reality Glasses group|OTHER: mural curtain group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Seaweed Extract on Postprandial Response to White Bread
Status: ACTIVE_NOT_RECRUITING
Conditions: Glycemic Control|Diabetes Mellitus Risk|Glucose Intolerance|Postprandial Hyperglycemia|Healthy Subjects
Interventions: DIETARY_SUPPLEMENT: Seaweed extract LD and white bread|DIETARY_SUPPLEMENT: Seaweed extract HD and white bread|DIETARY_SUPPLEMENT: White bread
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Fractional Photothermolysis for Hair Follicle Induction
Status: ACTIVE_NOT_RECRUITING
Conditions: Alopecia
Interventions: DEVICE: Fraxel Dual laser|DEVICE: Halo laser
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ipilimumab Administered to Stage IIIC Stage IV Melanoma After Reg. T Cell Depletion With Denileukin Diftitox
Status: TERMINATED
Conditions: Metastatic Melanoma
Interventions: DRUG: Ipilimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Can the Venus 1000 Help Clinicians Treat Patients With Severe Sepsis or Acute Heart Failure? The CVP Trial
Status: UNKNOWN
Conditions: Severe Sepsis|Acute Heart Failure
Interventions: DEVICE: Mespere Venus 1000 Non-Invasive CVP System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Adjustment of Mask Pressure, for Bilevel Positive Airways Pressure Therapy, by Automated Algorithm
Status: COMPLETED
Conditions: Respiratory Insufficiency|Sleep Disordered Breathing
Interventions: DEVICE: AutoVPAP with addition of AutoEPAP|DEVICE: AutoVPAP with EPAP manually selected
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Descriptive Analysis of Clinical Outcomes in Patients With Prostate Gland Cancer, Which Spreads to Other Parts of the Body, Who Were Treated First With Novel Anti-hormone Therapy Followed by a Second Line Treatment With Novel Anti-Hormone Therapy or RadIum-223 (Xofigo).
Status: COMPLETED
Conditions: Metastatic Castration-resistant Prostate Cancer (mCRPC)
Interventions: DRUG: Radium-223 (Xofigo, BAY88-8223)|DRUG: Abiraterone|DRUG: Enzalutamide
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Radiofrequency Applications and Alcoholic Neurolysis of Genicular Nerve for the Treatment of Knee Osteoarthritic Pain
Status: RECRUITING
Conditions: Radiofrequency|Alcohol|Genicular Nerve|Knee Osteoarthritis|Pain
Interventions: DEVICE: Radiofrequency|DRUG: Alcohol 30%|DRUG: Alcohol 50%|DRUG: Alcohol 70%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Combination Therapy With Guselkumab and Golimumab in Participants With Moderately to Severely Active Ulcerative Colitis
Status: ACTIVE_NOT_RECRUITING
Conditions: Colitis, Ulcerative
Interventions: BIOLOGICAL: Guselkumab|BIOLOGICAL: Golimumab|BIOLOGICAL: JNJ-78934804|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Sevoflurane and Percutaneous Coronary Intervention by Stent
Status: TERMINATED
Conditions: Myocardial Infarction
Interventions: DRUG: sevoflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Performance of Two Cad-cam Fabricated Ceramic Restoration in Teeth Affected With MIH
Status: COMPLETED
Conditions: Molar Incisor Hypomineralization
Interventions: PROCEDURE: occlusal veneer restorations|PROCEDURE: endocrown restorations
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Olverembatinib Combined With Reduced-Intensity Chemotherapy and Venetoclax for de Novo Ph+ ALL
Status: RECRUITING
Conditions: Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia
Interventions: DRUG: Olverembatinib|DRUG: Venetoclax|DRUG: prednisone|DRUG: Vincristine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Carboplatin and Irinotecan in Treating Children With Refractory Solid Tumors
Status: COMPLETED
Conditions: Unspecified Childhood Solid Tumor, Protocol Specific
Interventions: DRUG: carboplatin|DRUG: irinotecan hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of TAK-559 in Treating Subjects With Type 2 Diabetes Mellitus
Status: TERMINATED
Conditions: Diabetes Mellitus
Interventions: DRUG: TAK-559|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Alternative Access Approaches for Transcatheter Aortic Valve Replace (TAVR) in Inoperable Patients With Aortic Stenosis
Status: COMPLETED
Conditions: Severe Symptomatic Aortic Stenosis
Interventions: DEVICE: Edwards SAPIEN Transcatheter Heart Valve
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Thrombolysis in Ischemic Spinal Cord Stroke
Status: TERMINATED
Conditions: Motor Weakness in Two or Four Limbs|Damage in the Anterior Spinal Artery (ASA)|Temperature and Superficial Sensation|Urinary Retention or Bowel Disorder
Interventions: DRUG: Intravenuse Alteplase
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Uric Acid in Essential Hypertension in Children
Status: COMPLETED
Conditions: Essential Hypertension
Interventions: DRUG: Allopurinol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Rt-PA Thrombolytic Therapy in Combination With Remote Ischemic Conditioning for Acute Ischemic Stroke
Status: COMPLETED
Conditions: Ischemic Stroke
Interventions: DEVICE: Remote ischemic conditioning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nutritional Evaluation of Canola Protein in Comparison With Soy Protein
Status: COMPLETED
Conditions: Men
Interventions: DIETARY_SUPPLEMENT: Protein drink - protein isolate|DIETARY_SUPPLEMENT: Protein drink - protein hydrolyzate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Effect of Empagliflozin Versus Placebo on Brain Insulin Sensitivity in Patients With Prediabetes
Status: COMPLETED
Conditions: PreDiabetes|Body Weight
Interventions: DRUG: Empagliflozin 25mg|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Survey of Physician and Molecular Tumor Board Perspectives on the Clinical Utility and Usability of Cellworks Singula™ and Ventura™ Reports in Facilitating Patient Treatment Decisions for Pan-Cancer Patients
Status: RECRUITING
Conditions: Pan-cancer
Interventions: OTHER: Cellworks Singula and Ventura reports
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Ultrasound to Prevent Leg Wound Complications in Heart Bypass.
Status: TERMINATED
Conditions: Surgical Wound Infection|Coronary Artery Bypass
Interventions: PROCEDURE: Ultrasound imaging of the long saphenous vein
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effects of rTMS on Respiratory Function and Gut Microbiota in Patients With Brain Injury
Status: NOT_YET_RECRUITING
Conditions: Brain Injuries|Respiratory Function Impaired|Gut Microbiota
Interventions: DEVICE: active rTMS|DEVICE: sham rTMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Nuts in Obese Children.
Status: TERMINATED
Conditions: Child Obesity
Interventions: DIETARY_SUPPLEMENT: wNUTS, low-caloric diet plus nuts|OTHER: w/oNUTS, low-caloric diet without nuts
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Phase I/II Trial of HER-2/Neu Pulsed DC1 Vaccine Combined With Trastuzumab for Patients With DCIS
Status: WITHDRAWN
Conditions: Breast Cancer
Interventions: BIOLOGICAL: HER-2 pulsed DC1|DRUG: trastuzumab|DRUG: pertuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Post-marketing Surveillance of Donepezil Hydrochloride - Investigation of Long Term Safety and Efficacy of Aricept as Well as Its Proper Use Information in Patients With Dementia With Lewy Bodies (DLB).
Status: COMPLETED
Conditions: Dementia With Lewy Body Disease
Interventions: DRUG: Donepezil Hydrochloride
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy of Metformin Versus Sitagliptin on Benign Thyroid Nodules in Type 2 Diabetes
Status: UNKNOWN
Conditions: Diabetes Mellitus, Type 2|Thyroid Nodule (Benign)
Interventions: DRUG: METFORMIN|DRUG: Sitagliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Wakȟáŋyeža (Little Holy One)
Status: RECRUITING
Conditions: Suicide|Trauma, Psychological|Parenting
Interventions: BEHAVIORAL: Newly created cultural components, adapted Family Spirit lessons, adapted CETA modules|BEHAVIORAL: Active nutrition control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Delafloxacin vs Vancomycin and Aztreonam for the Treatment of Acute Bacterial Skin and Skin Structure Infections
Status: COMPLETED
Conditions: Skin and Subcutaneous Tissue Bacterial Infections|Skin Structures and Soft Tissue Infections
Interventions: DRUG: delafloxacin|DRUG: vancomycin|DRUG: aztreonam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Dazostinag as Single Agent and Dazostinag in Combination With Pembrolizumab in Adults With Advanced or Metastatic Solid Tumors
Status: RECRUITING
Conditions: Solid Neoplasms
Interventions: DRUG: Dazostinag|DRUG: Pembrolizumab|DRUG: Platinum|DRUG: 5-fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Gunnar Computer Glasses on Viewing Comfort and Performance
Status: TERMINATED
Conditions: Dry Eye|Eye Strain|Visual Acuity|Color Perception|Reading
Interventions: DEVICE: Gunnar OTC Glasses Condition
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Long-Term Follow-up of Tandem High-Dose Therapy With Peripheral Blood Stem Cell for Adults With High-Risk Age-Adjusted IPI Aggressive Non-Hodgkin's Lymphomas
Status: COMPLETED
Conditions: Lymphoma
Interventions: DRUG: CEEP regimen|PROCEDURE: Tandem high-dose therapy (HDT) followed by autologous peripheral blood stem cell (PBSC)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endoesophageal Cryotherapy For Ablating Barrett's Esophagus and Early Stage Esophageal Cancer
Status: UNKNOWN
Conditions: Barrett's Esophagus
Interventions: PROCEDURE: Endoscopic spray cryotherapy|PROCEDURE: Endoscopic spray cryotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Manchester Intermittent and Daily Diet Type 1 Diabetes App Study (MIDDAS-Type 1)
Status: RECRUITING
Conditions: Type 1 Diabetes|Obesity
Interventions: DIETARY_SUPPLEMENT: Optifast meal replacement shakes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Cooled Radiofrequency for the Treatment of Hip Pain Associated With Hip OA Compared to Intra-articular Steroid Injections
Status: UNKNOWN
Conditions: Osteoarthritis, Hip
Interventions: PROCEDURE: Cooled RFA treatment with COOLIEF* device|DRUG: intra-articular corticosteroid injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bortezomib and Temozolomide in Treating Patients With Brain Tumors or Other Solid Tumors That Have Not Responded to Treatment
Status: COMPLETED
Conditions: Brain and Central Nervous System Tumors|Lymphoma|Metastatic Cancer|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: bortezomib|DRUG: temozolomide|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Controlled Trial of Doxycycline to Prevent Acquisition of Mycoplasma Pneumoniae in an Outbreak Setting
Status: COMPLETED
Conditions: Mycoplasma Pneumoniae
Interventions: DRUG: Doxycycline treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose:
Clinical trial: Safety and Quality of Life Study of Aflibercept in Patients With Metastatic Colorectal Cancer Previously Treated With an Oxaliplatin-Based Regimen
Status: COMPLETED
Conditions: Colorectal Cancer Metastatic
Interventions: DRUG: AFLIBERCEPT AVE0005|DRUG: FOLFIRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Quetiapine Fumarate Bipolar Maintenance Monotherapy
Status: COMPLETED
Conditions: Bipolar Disorder
Interventions: DRUG: quetiapine fumarate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Safety of Esketamine in Elective Laparoscopic Surgery
Status: COMPLETED
Conditions: Laparoscopy|Anesthesia, Intravenous
Interventions: DRUG: BT-KTM-I|DRUG: Ketanest®S
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CINSARC Signature and Correlation With Hemotherapy Efficacy in Soft-tissue Sarcomas. A Biomarker Study.
Status: RECRUITING
Conditions: Soft-tissue Sarcomas
Interventions: OTHER: Procedure/Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study To Evaluate The Efficacy And Safety Of Oral PF-06651600 And PF-06700841 In Subjects With Moderate To Severe Crohn's Disease
Status: COMPLETED
Conditions: Crohn's Disease
Interventions: DRUG: PF-06651600 Placebo|DRUG: PF-06651600|DRUG: Placebo PF-06700841|DRUG: PF-06700841
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety and Immunogenicity of GlaxoSmithKline Biologicals' Influenza Vaccine in Elderly People
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: GSK investigational vaccine 2186877A|BIOLOGICAL: FluarixTM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of the Efficacy, Safety and Tolerability Profile of CSL Limited's Influenza Virus Vaccine (CSL's IVV) Administered Intramuscularly in Healthy Adults
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: CSL Limited Influenza Vaccine|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: AC105 in Patients With Acute Traumatic Spinal Cord Injury
Status: TERMINATED
Conditions: Acute Spinal Cord Injury
Interventions: DRUG: AC105|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Suprachoroidal Injection of Triamcinolone Acetonide With IVT Aflibercept in Subjects With Macular Edema Following RVO
Status: COMPLETED
Conditions: Macular Edema|Retinal Vein Occlusion
Interventions: DRUG: 4 mg CLS-TA|DRUG: Sham|DRUG: IVT aflibercept
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Metformin in Obese Non-diabetic Pregnant Women
Status: COMPLETED
Conditions: Pregnancy Complications|Obesity
Interventions: DRUG: Metformin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Self-Care Insufficiency Care Model and Mobile Application Supported Care on Symptoms and Quality of Life of Gastrointestinal Cancer Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Nursing Care for Gastrointestinal Cancer Patients
Interventions: OTHER: routine care group|OTHER: Care in accordance with Orem's theory group
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Multicenter, Double-blind, Parallel Phase III Study
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: GC3110A(Quadrivalent)|BIOLOGICAL: GC Flu(Trivalent)|BIOLOGICAL: GC3110A(Trivalent)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Project Attention Deficit Hyperactivity Disorder (ADHD) and Electroencephalography (EEG)-Neurofeedback THERapy
Status: COMPLETED
Conditions: ADHD
Interventions: OTHER: Placebo EEG Neurofeedback|OTHER: EEG-Neurofeedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Emergency (Red Code) Cesarean Section : Maternal and Fetal Prognosis Depending on Anesthetic Modalities in a Level 3 Maternity Ward
Status: COMPLETED
Conditions: Anesthesia Complication
Interventions: PROCEDURE: epidural anesthesia|PROCEDURE: general anesthesia
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Clinical Activity Study of Combination Azacitidine and Avelumab in Patients With Acute Myeloid Leukemia (AML) and Minimal Residual Disease (MRD)
Status: WITHDRAWN
Conditions: Acute Myeloid Leukemia (AML)|Minimal Residual Disease
Interventions: DRUG: Azacitidine|DRUG: Avelumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic/Pharmacodynamic Study of 3 Subcutaneous Single Dose Epoetin Alfa Formulations in Healthy Volunteers
Status: COMPLETED
Conditions: Anemia
Interventions: DRUG: Epoetin Alfa 40000 UNT/ML
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: E. Coli Nissle in Oncology
Status: COMPLETED
Conditions: Gastric Cancer|Colorectal Cancer
Interventions: DRUG: E. coli Nissle suspension|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Bispectral Index and Levels of Sedation With Propofol With/Without Remifentanil in Healthy Volunteers (SONORA)
Status: COMPLETED
Conditions: Anesthesia
Interventions: DEVICE: BIS
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Testing AZD1775 inC Combination With Radiotherapy and Chemotherapy in Cervical, Upper Vaginal and Uterine Cancers
Status: TERMINATED
Conditions: Cervical Carcinoma|Endometrioid Adenocarcinoma|Malignant Female Reproductive System Neoplasm|Recurrent Cervical Carcinoma|Stage I Uterine Corpus Cancer AJCC v7|Stage I Vaginal Cancer AJCC v6 and v7|Stage IA Uterine Corpus Cancer AJCC v7|Stage IB Cervical Cancer AJCC v6 and v7|Stage IB Uterine Corpus Cancer AJCC v7|Stage IB2 Cervical Cancer AJCC v6 and v7|Stage II Cervical Cancer AJCC v7|Stage II Uterine Corpus Cancer AJCC v7|Stage II Vaginal Cancer AJCC v6 and v7|Stage IIA Cervical Cancer AJCC v7|Stage IIB Cervical Cancer AJCC v6 and v7|Stage III Cervical Cancer AJCC v6 and v7|Stage III Uterine Corpus Cancer AJCC v7|Stage III Vaginal Cancer AJCC v6 and v7|Stage IIIA Cervical Cancer AJCC v6 and v7|Stage IIIA Uterine Corpus Cancer AJCC v7|Stage IIIB Cervical Cancer AJCC v6 and v7|Stage IIIB Uterine Corpus Cancer AJCC v7|Stage IIIC Uterine Corpus Cancer AJCC v7|Vaginal Carcinoma
Interventions: DRUG: Adavosertib|DRUG: Cisplatin|RADIATION: External Beam Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Amifostine and Melphalan in Treating Patients With Primary Systemic Amyloidosis Who Are Undergoing Peripheral Stem Cell Transplantation
Status: TERMINATED
Conditions: Drug/Agent Toxicity by Tissue/Organ|Multiple Myeloma and Plasma Cell Neoplasm
Interventions: BIOLOGICAL: filgrastim|DRUG: amifostine trihydrate|DRUG: melphalan|PROCEDURE: bone marrow ablation with stem cell support|PROCEDURE: peripheral blood stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of Bimekizumab Compared to an Active Comparator in Adult Subjects With Moderate to Severe Chronic Plaque Psoriasis
Status: COMPLETED
Conditions: Chronic Plaque Psoriasis|Moderate to Severe Chronic Plaque Psoriasis
Interventions: DRUG: Bimekizumab|DRUG: Secukinumab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study on the Safety, Efficacy of Home RF Cosmetic Instrument in the Treatment of Facial or Periorbital Wrinkles（F-MFR300-RD-003）
Status: COMPLETED
Conditions: Skin Wrinkles
Interventions: DEVICE: Home radiofrequency skin treatment instrument|OTHER: Ultrasonic coupler for medical purposes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Peer Led Outreach to Engage Male Partners of Pregnant Women in Uganda (Okutuuka Study)
Status: COMPLETED
Conditions: Engagement, Patient|Male Peer Recruitment|HIV Testing|Linkage to Care
Interventions: BEHAVIORAL: Male peer engagement|BEHAVIORAL: SOC and delayed intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Optimize Heart Failure Care During TRANSitional Period in Patients With Acute Heart Failure.
Status: UNKNOWN
Conditions: Heart Failure With Reduced Ejection Fraction|Acute Heart Failure
Interventions: OTHER: Checklist|OTHER: Education|OTHER: Telephone monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long Term Immunogenicity of Quadrivalent Human Papillomavirus Vaccine (Gardasil®)in HIV-infected Adolescents and Young Adults
Status: UNKNOWN
Conditions: HPV|HIV
Interventions: BIOLOGICAL: Quadrivalent Human Papillomavirus (6, 11, 16 and 18) vaccine (Gardasil ®)|BIOLOGICAL: Quadrivalent Human Papillomavirus (6, 11, 16 and 18) vaccine (Gardasil ®)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effect of Interscalene Peripheral Nerve Block With 0.25% Bupivacaine vs 0.125% Bupivacaine on Lung Function
Status: COMPLETED
Conditions: Diaphragm Paralysis
Interventions: DRUG: interscalene nerve block with 0.25% bupivacaine|DRUG: interscalene block with 0.125% bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Radiolabeled Monoclonal Antibody Therapy After Radiation Therapy in Treating Patients With Primary Brain Tumors
Status: COMPLETED
Conditions: Brain and Central Nervous System Tumors|Neuroblastoma
Interventions: DRUG: carmustine|DRUG: irinotecan hydrochloride|PROCEDURE: surgical procedure|RADIATION: iodine I 131 monoclonal antibody 81C6
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: DF(Oat Bran) Intervention on Inflammation, Intestinal Flora, Disease Activity and Quality of Life in Patients With RA
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DIETARY_SUPPLEMENT: Oat bran (dietary fiber)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study to Evaluate the Role of EBUS in the Diagnosis of Acute PE in Critically Ill Patients
Status: ENROLLING_BY_INVITATION
Conditions: Acute Pulmonary Embolism
Interventions: DEVICE: Endobronchial ultrasound (EBUS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Sofosbuvir and Daclatasvir in Treating Hepatitis C, A Study on 1000 Patients
Status: COMPLETED
Conditions: Hepatitis C
Interventions: DRUG: sofosbuvir and daclatasvir
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Linaclotide in Patients With Overlapping Functional Gastrointestinal Disorders
Status: UNKNOWN
Conditions: Functional Dyspepsia|Constipation-predominant Irritable Bowel Syndrome
Interventions: DRUG: Linaclotide|DRUG: Lactulose|DRUG: Omeprazol|DRUG: Itopride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sulforaphane in Treating Patients With Recurrent Prostate Cancer
Status: COMPLETED
Conditions: Adenocarcinoma of the Prostate|Recurrent Prostate Cancer
Interventions: DRUG: Sulforaphane|OTHER: Laboratory biomarker analysis|OTHER: Pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study for Participants With Small-Cell Lung Cancer
Status: COMPLETED
Conditions: Small Cell Lung Cancer
Interventions: DRUG: LY2523355|DRUG: Granulocyte colony-stimulating factor (G-CSF)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Pharmacokinetics of AVL-292 Following Multiple Doses and the Effect of Food on the Single-dose Pharmacokinetics of AVL-292
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: 50 mg AVL-292|DRUG: 100 mg AVL-292|DRUG: 200 mg AVL-292|DRUG: 350 mg AVL-292|DRUG: Placebo capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: The Emirates Heart Health Project: A Family-based Diet and Exercise Intervention in Obese and Overweight Patients
Status: UNKNOWN
Conditions: Overweight and Obesity|Cardiovascular Risk Factor
Interventions: BEHAVIORAL: Family-based diet and exercise intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Randomized, Double-Blinded, Placebo-Controlled Trial of Corticosteroid Therapy Following Portoenterostomy
Status: COMPLETED
Conditions: Biliary Atresia
Interventions: DRUG: Corticosteroids|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Cervix as a Natural Tamponade in Postpartum Hemorrhage Caused by Placenta Previa and Placenta Previa Accreta
Status: UNKNOWN
Conditions: Placenta Previa|Placenta Previa Accreta
Interventions: PROCEDURE: The cervix as a natural tamponade (cervical inversion)
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Effect of Galantamine on Inflammation and Cognition
Status: COMPLETED
Conditions: HIV Associated Cognitive Motor Complex
Interventions: DRUG: Galantamine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Role of Gut Bacteria in the Immune Response to Vaccination in Patients With Ulcerative Colitis
Status: ACTIVE_NOT_RECRUITING
Conditions: Ulcerative Colitis
Interventions: DIETARY_SUPPLEMENT: Dietary Fiber Mixture|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Nylon Flocked Swabs and Saline Aspirates for Detection Respiratory Viruses
Status: UNKNOWN
Conditions: Respiratory Syncytial Virus|Human Metapneumovirus|Influenza|Bronchiolitis|Pediatric
Interventions: DEVICE: Nylon Flocked swab (Nasal secretion sampling)|DEVICE: Nylon Flocked swab (Nasal secretion sampling)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Impact of a Smartphone Intervention on Tanzanian Women's Childbirth Location
Status: COMPLETED
Conditions: Maternal Death Affecting Fetus or Newborn|Delivery Complication|Obstetric Complication|Birth Injuries|Delivery; Injury, Maternal|Delivery Problem for Fetus
Interventions: BEHAVIORAL: SUSTAIN Smartphone training of CHW (SP+)|BEHAVIORAL: SUSTAIN Paperbased training of CHW (SOC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Pharmacokinetics and Pharmacodynamics of Linezolid Continuous and Intermittent Administration
Status: RECRUITING
Conditions: Side-effect of Antibiotic|Efficacy|Pharmacokinetics|Critical Illness|Intensive Care Unit ICU
Interventions: OTHER: Linezolid continuous infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Advanced or Metastatic Triple-negative Breast Cancer With Adoptive Therapy of PD1+ TILS
Status: RECRUITING
Conditions: Metastatic Triple-Negative Breast Carcinoma
Interventions: DRUG: PD1+ TILs (NUMARZU-001) product infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluate HM-002-1005 in Subjects With Type 2 Diabetes Mellitus
Status: RECRUITING
Conditions: Diabetes Mellitus, Type II
Interventions: DRUG: HM-002-1005
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Dose-finding Phase IIb Study With AZD0865 and Esomeprazole in GERD Patients Without Erosive Esophagitis.
Status: COMPLETED
Conditions: GERD Without Erosive Esophagitis
Interventions: DRUG: AZD0865
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Effect of Oral Collagen Tripeptide on Skin Moisture and Wrinkles in Adult Women
Status: COMPLETED
Conditions: Skin Manifestations|Skin Wrinkling
Interventions: DIETARY_SUPPLEMENT: CTP|DIETARY_SUPPLEMENT: placebo (starch)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: PD-L1 Inhibitor Rechallenge After PD-1 Immunotherapy for Patients With Solid Tumor Beyond Lung Cancer
Status: UNKNOWN
Conditions: Efficacy|Safety
Interventions: DRUG: PD-L1 inhibitor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Neuro-Stim System on Pain, Sleep, and Opioid Use
Status: TERMINATED
Conditions: Pain (Visceral, Somatic, or Neuropathic)
Interventions: DEVICE: Experimental NSS|DEVICE: Sham NSS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bitter Chocolate or Orange Juice for Non-reactive Non-stress Test (NST) Patterns
Status: COMPLETED
Conditions: Nonreassuring Fetal Status
Interventions: DIETARY_SUPPLEMENT: Bitter chocolate|DIETARY_SUPPLEMENT: Orange juice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose:
Clinical trial: Possible Effects of Supplement Therapy With Oral Phenolics on Cluster of Differentiation 163 (CD-163) Biomarker of Patients With Age-related Macular Degeneration
Status: UNKNOWN
Conditions: Age Related Macular Degeneration
Interventions: DRUG: Oral intake of medication|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: The Comparison of 50% AS Versus PFAT+ 0.05 % COE in Severe Dry Eye Syndrome
Status: COMPLETED
Conditions: Dry Eye Syndrome
Interventions: DRUG: COE 2*1 (Restasis) + PFAT Refresh Single dose) 8*1|BIOLOGICAL: AS 50% eye drops 8*1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: El DORADO STUDY (Evaluation of Delivery of Oxygen on Renal, Arrhythmia and Delirium Outcomes Study)
Status: RECRUITING
Conditions: AKI|Neurocognitive Disorders|Atrial Fibrillation
Interventions: DEVICE: Edwards ClearSight and Masimo SET
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Diagnostic Laparoscopy in the Preoperative Staging of Pancreatobiliary Cancer
Status: UNKNOWN
Conditions: Pancreatic Cancer
Interventions: PROCEDURE: Staging Laparoscopy|DEVICE: Laparoscopic ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Single Oral Dose Study Of PF-06427878 In Healthy Adult Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: PF-06427878|DRUG: Placebo|DRUG: PF-06427878|DRUG: Placebo|DRUG: PF-06427878|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Platelet Rich Plasma VS Platelet Fibrin Plasma in Treatment of Diabetes Related Wound：a Randomized Controlled Trial
Status: RECRUITING
Conditions: Diabetic Foot
Interventions: DEVICE: Platelet Fibrin Plasma|DEVICE: Platelet Rich Plasma
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Medication Reconciliation in Pulmonary Hypertension
Status: COMPLETED
Conditions: Pulmonary Hypertension|Pulmonary Hypertension Chronic Thromboembolic|Pulmonary Arterial Hypertension
Interventions: OTHER: Medication reconciliation|OTHER: Medication reconciliation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Evaluate the Effect of ASP1941 in Combination With Metformin in Adult Patients With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: ipragliflozin|DRUG: Placebo|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Allogeneic ABCB5-positive Stem Cells for Treatment of DFU "Malum Perforans"
Status: COMPLETED
Conditions: Diabetic Neuropathic Ulcer
Interventions: BIOLOGICAL: allo-APZ2-DFU
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Itopride Hydrochloride in Diabetes: Effects on Gastric Emptying and Glycemia
Status: COMPLETED
Conditions: Gastroparesis
Interventions: DRUG: Itopride|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Study of Amcenestrant (SAR439859) Versus Physician's Choice in Locally Advanced or Metastatic ER-positive Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer Metastatic
Interventions: DRUG: Amcenestrant|DRUG: Fulvestrant|DRUG: Anastrozole|DRUG: Letrozole|DRUG: Exemestane|DRUG: Tamoxifen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of TACE Combined With Camrelizumab in the Treatment of HCC Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: TACE combined with Camrelizumab|PROCEDURE: TACE plus Camrelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Jet Injectors Versus Conventional Anesthetic Technique in Children
Status: COMPLETED
Conditions: Anesthesia
Interventions: OTHER: Group I A (Conventional needle syringe)|OTHER: Group I B (Conventional needle syringe)|DEVICE: Group II A (Comfort-in Jet Injector)|DEVICE: Group II B (Comfort-in Jet Injector)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: PD-1 Inhibitor or PD-1 Inhibitor Plus GVD for Relapsed/Refractory CHL
Status: RECRUITING
Conditions: Classical Hodgkin Lymphoma|Refractory or Relapsed Classical Hodgkin Lymphoma
Interventions: DRUG: PD-1 inhibitor|DRUG: PD-1 inhibitor, gemcitabine, vinorelbine and doxorubicin liposome
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stanford Neuromodulation Therapy (SNT) for Non-suicidal Self-injury (NSSI)
Status: RECRUITING
Conditions: Transcranial Magnetic Stimulation|Non-suicidal Self-injury
Interventions: DEVICE: Transcranial Magnetic Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: rhBNP in Type 3 Pulmonary Hypertension
Status: ENROLLING_BY_INVITATION
Conditions: Group 3 Pulmonary Hypertension
Interventions: DRUG: recombinant human brain natriuretic peptide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I/II Study With CEA(6D) VRP Vaccine in Patients With Advanced or Metastatic CEA-Expressing Malignancies
Status: COMPLETED
Conditions: Colorectal Cancer|Breast Cancer|Lung Cancer|Pancreatic Cancer|Colon Cancer
Interventions: BIOLOGICAL: AVX701|BIOLOGICAL: AVX701|BIOLOGICAL: AVX701|BIOLOGICAL: AVX701|BIOLOGICAL: AVX701
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bronchodilator Effects and Safety of Glycopyrronium Bromide (25 ug and 50 ug o.d.) in Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: NVA237 (glycopyrronium bromide)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: In Vivo Succinate Detection After External Beam Radiation Therapy in SDHx- Paragangliomas
Status: RECRUITING
Conditions: Paraganglioma of Head and Neck
Interventions: DIAGNOSTIC_TEST: 1H-Spectroscopy MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation of Spironolactone Efficacy in Patient With Rheumatoid Arthritis (RA)
Status: RECRUITING
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Spironolactone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT