pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Smartphone Application for University Students With Binge Drinking Behavior
Status: RECRUITING
Conditions: Alcohol Drinking|Binge Drinking
Interventions: BIOLOGICAL: blood microsampling
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Natural Seawater Based Throat Spray in Acute Sore Throat Relief
Status: UNKNOWN
Conditions: Sore Throat
Interventions: DEVICE: Angiflash|DEVICE: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intern Health Study 2021
Status: COMPLETED
Conditions: Telemedicine
Interventions: BEHAVIORAL: Intern Health Study competition-related mobile notification|BEHAVIORAL: Intern Health Study mobile app|BEHAVIORAL: Intern Health Study mobile app competition scoreboard and history
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ALiskiren or Losartan Effects on bioMARKers of Myocardial Remodeling
Status: COMPLETED
Conditions: Hypertension|Left Ventricle Hypertrophy
Interventions: DRUG: Aliskiren|DRUG: Losartan|DRUG: Amlodipine|DRUG: Hydrochlorothiazide (HCTZ)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Omeprazole and Reflux Disease - Improvement of Clinical Outcome by Genotype-adjusted Dosing
Status: TERMINATED
Conditions: Gastroesophageal Reflux
Interventions: DRUG: omeprazole|DRUG: omeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Antiplaque, Antigingivitis and Anti-inflammatory Effects of Myrrh Mouthwash
Status: COMPLETED
Conditions: Gingivitis|Dental Plaque
Interventions: DRUG: Myrrh mouthwash|DRUG: Chlorhexidine mouthwash|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Application and Effect Evaluation of Medium Chain Fatty Acid Rich Milk Powder in Infants With Cholestatic Liver Disease
Status: NOT_YET_RECRUITING
Conditions: Cholestatic Liver Disease
Interventions: DIETARY_SUPPLEMENT: Rich medium chain fatty acid milk powder group|DIETARY_SUPPLEMENT: Regular milk powder group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pembrolizumab +/- SD-101 in Hormone-Naïve Oligometastatic Prostate Cancer With RT and iADT
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostatic Neoplasms
Interventions: DRUG: Pembrolizumab|DRUG: SD-101|DRUG: Leuprolide acetate|DRUG: Abiraterone Acetate|DRUG: Prednisone|RADIATION: Stereotactic Body Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BREMEN Eye Drops Versus Combigan for Open-angle Glaucoma or Intraocular Hypertension
Status: COMPLETED
Conditions: Ocular Hypertension|Primary Open-angle Glaucoma
Interventions: DRUG: BREMEN eye drops|DRUG: Combigan®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized Controlled Comparative Study of Ultrasound-guided Paravertebral Blocks as Part of a Multimodal Regimen for Ambulatory Breast Cancer Surgery
Status: UNKNOWN
Conditions: Breast Diseases
Interventions: OTHER: Paravertebral Blocks (PVB)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Correlation Intraocular Pressure With Intracranial Pressure
Status: UNKNOWN
Conditions: Intraocular Pressure|Intracranial Pressure Increase|Trauma, Brain|Children, Only
Interventions: DIAGNOSTIC_TEST: with intraocular pressure high|DIAGNOSTIC_TEST: without intraocular pressure high
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Opioid Reduction in Orthopaedic Surgery (OREOS) - Knees
Status: ACTIVE_NOT_RECRUITING
Conditions: Knee Osteoarthritis|Chronic Post Operative Pain
Interventions: OTHER: Multicomponent opioid reduction and pain management pathway|OTHER: Standard care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Analysis of Simultaneous Pancreas-kidney Transplantation for End-stage Renal Disease Associated With Diabetes Mellitus
Status: UNKNOWN
Conditions: Diabetes Mellitus；Uremia
Interventions: PROCEDURE: simultaneous pancreas-kidney transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Visual Performance Measures in a Virtual Reality Environment for Assessing Clinical Trial Outcomes in Those With Severely Reduced Vision
Status: UNKNOWN
Conditions: Low Vision|Retinitis Pigmentosa|Stargardt Disease 1|Stargardt Disease 3|Stargardt Disease 4|Albinism
Interventions: DEVICE: Virtual Reality Headset based tests
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Platinum Doublet Chemotherapy and Proton Beam Radiation Therapy in Treating Patients With Stage II-III Non-small Cell Lung Cancer That Cannot Be Removed by Surgery
Status: COMPLETED
Conditions: Recurrent Lung Non-Small Cell Carcinoma|Stage II Lung Cancer AJCC v8|Stage III Lung Cancer AJCC v8|Unresectable Lung Non-Small Cell Carcinoma
Interventions: DRUG: Carboplatin|DRUG: Cisplatin|DRUG: Etoposide|DRUG: Paclitaxel|DRUG: Pemetrexed|RADIATION: Proton Beam Radiation Therapy|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Failed Retrograde Cholangiopancreatography (ERCP) Stone Extraction: Surgical Interference
Status: NOT_YET_RECRUITING
Conditions: Common Bile Duct Calculi
Interventions: PROCEDURE: Endoscopic stenting Retrograde Cholangiopancreatography (ERCP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Licorice Root Extract and Pomegranate Juice on Atherosclerotic Parameters in Diabetic Patients
Status: UNKNOWN
Conditions: Diabetes Mellitus|Atherosclerosis
Interventions: DRUG: Licorice root extract or Pomegranate juice
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multicenter Prospective Randomized Controlled Trial of Plicated Laparoscopic Adjustable Gastric Banding
Status: TERMINATED
Conditions: Morbid Obesity
Interventions: DEVICE: Standard-LAGB|DEVICE: Plicated-LAGB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Addition of Chloroquine to Chemoradiation for Glioblastoma
Status: COMPLETED
Conditions: Glioblastoma Multiforme
Interventions: DRUG: Chloroquine|RADIATION: Radiotherapy|DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Haploidentical Stem Cell Transplantation for Children With Acquired Severe Aplastic Anemia
Status: UNKNOWN
Conditions: Acquired Aplastic Anemia
Interventions: DRUG: Fludarabine|DRUG: Cyclophosphamide|BIOLOGICAL: anti-thymocyte globulin|BIOLOGICAL: filgrastim|RADIATION: Total body irradiation|PROCEDURE: CD3-depleted hematopoietic cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Phenylketonuria-type Diet on Appetite, Appetite Hormones and Diet Induced Thermogenesis
Status: COMPLETED
Conditions: Phenylketonuria (PKU)
Interventions: DIETARY_SUPPLEMENT: Phenylketonuria-type diet|OTHER: Normal (control) diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: Adjusted Value of Thromboprophylaxis in Hospitalized Obese Patients: A Comparative Study of Two Regimens of Enoxaparin
Status: COMPLETED
Conditions: Thromboprophylaxis in Hospitalized Obese Patients
Interventions: DRUG: Enoxaparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Personalized Dietary Advice After Discharge From Hospital in Geriatrics: Factors Associated With Improved Nutritional Status and Autonomy
Status: UNKNOWN
Conditions: Undernutrition of Elderly Peopole
Interventions: DIETARY_SUPPLEMENT: Personalized dietary management at home
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study of Olaparib and Durvalumab in IDH-Mutated Solid Tumors
Status: RECRUITING
Conditions: Glioma|Cholangiocarcinoma|Solid Tumor|IDH Mutation
Interventions: DRUG: Olaparib|DRUG: Durvalumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RCT of a Neuroplasticity Agent and CI Therapy for Severe Arm Paresis After Stroke
Status: WITHDRAWN
Conditions: Severe Stroke With Affected Arm Motor Function
Interventions: DRUG: Fluoxetine|DRUG: Placebo|PROCEDURE: eCMIT|PROCEDURE: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Biomarkers of Dementia in Chronic Sleep and Breathing Disorders
Status: RECRUITING
Conditions: COPD|Overlap Syndrome|OSA
Interventions: DIAGNOSTIC_TEST: High density electroencephalogram (HdEEG)|DIAGNOSTIC_TEST: Functional near infrared spectroscopy (fNIRS)|DIAGNOSTIC_TEST: Magnetic resonance imaging (MRI)|BIOLOGICAL: Blood collection|DIAGNOSTIC_TEST: Neuropsychological battery|OTHER: Questionnaires|DIAGNOSTIC_TEST: Pulmonary Function Test (PFT)|OTHER: Cognitive Assessment|DIAGNOSTIC_TEST: Polysomnogram (PSG)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Postoperative Analgesia Using Ganglion Impar Block After Anal Surgery
Status: NOT_YET_RECRUITING
Conditions: Postoperative Pain
Interventions: PROCEDURE: Ganglion impar block with Bupivacaine.|PROCEDURE: Ganglion impar block with normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neuro-cardiac Rehabilitation in Youth With Congenital Heart Disease (QUALINEUROREHAB)
Status: NOT_YET_RECRUITING
Conditions: Congenital Heart Disease
Interventions: OTHER: Neurocardiac rehabilitation program|OTHER: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: İntraoperative Awareness Under General Anesthesia
Status: UNKNOWN
Conditions: To Investigate the Incidence and Causes of Awareness During General Anesthesia|To Investigate the of Dreaming During Anesthesia|To Investigate the Intra-operative Experiences of Patients Who Report Awareness|To Investigate the Risk Factors That May be Associated With Awareness|To Analyze the Frequency of Posttraumatic Stress Disorder in Cases With Awareness and Possible Awareness|To Investigate the Risk Factors That May be Associated With Posttraumatic Stress Disorder
Interventions: OTHER: General anesthesia
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Virtual Surgical Planning in Mandibular Segmental Resection
Status: RECRUITING
Conditions: Virtual Surgical Planning|Benign Neoplasm|Mandible
Interventions: PROCEDURE: Traditional Medthod|PROCEDURE: Virtual surgical planning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: HIV and Alcohol Research Center Focused on Polypharmacy (HARP) Pilot 1
Status: COMPLETED
Conditions: HIV|Alcohol Use
Interventions: BEHAVIORAL: IMB-motivational interviewing (MI) techniques (IMB-MI)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Two Interforaminal Implants in an Immediate or Delayed Loading Protocol for the Elderly
Status: COMPLETED
Conditions: Edentulous Jaw
Interventions: PROCEDURE: Implant placement|PROCEDURE: immediate loading|PROCEDURE: conventional loading
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Novel Erythropoiesis Stimulating Protein (NESP; Darbopoetin Alfa) for the Treatment of Anemia in Lung Cancer Patients Receiving Multi-cycle Platinum-Containing Chemotherapy
Status: COMPLETED
Conditions: Anemia
Interventions: DRUG: Darbepoetin alfa|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Trial for Optimal Number of Passes Required for Molecular Profiling During EUS-FNB of Pancreatic Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Pancreatic Cancer|Pancreatic Neoplasms|Adenocarcinoma of the Pancreas
Interventions: PROCEDURE: 2 passes during EUS-guided fine needle biopsy|PROCEDURE: 3 passes during EUS-guided fine needle biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Sodium Citrate in Smell Retraining for People With Post-COVID-19 Olfactory Dysfunction
Status: RECRUITING
Conditions: Long Haul COVID-19|Post-Acute COVID-19 Syndrome|Anosmia|Olfaction Disorders
Interventions: DRUG: Sodium Citrate|DRUG: Normal Saline|OTHER: Olfactory Training Kit - "The Olfactory Kit, by AdvancedRx"
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: N-Acetyl-Cysteine (NAC) in Early Phase Schizophrenia Spectrum Psychosis
Status: COMPLETED
Conditions: Schizophrenic Psychoses
Interventions: DRUG: n-acetylcysteine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Michigan Emergency Department Improvement Collaborative (MEDIC) Alert; Pulmonary Embolism (PE)
Status: ACTIVE_NOT_RECRUITING
Conditions: Pulmonary Embolism
Interventions: BEHAVIORAL: Pulmonary Embolism (PE) Care in Emergency Department (ED)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Comparison Between Colorectal Stents and Primary Surgery in Obstructive Colonic Cancer. A Randomized, Controlled Study
Status: TERMINATED
Conditions: Colorectal Obstruction|Left Colonic Adenocarcinoma
Interventions: PROCEDURE: stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anterior Capsulectomy vs. Repair in Direct Anterior THA
Status: COMPLETED
Conditions: Total Hip Arthroplasty
Interventions: PROCEDURE: Direct anterior approach with capsulectomy|PROCEDURE: Direct anterior approach without capsulectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Cost-effectiveness of Different Caries Preventive Protocols
Status: NOT_YET_RECRUITING
Conditions: Caries Prevention
Interventions: DRUG: Fluoride based varnish (Dentkist Charm Fill Varnish )|DRUG: pro care gel remineralizing agent|DEVICE: Mobile application|COMBINATION_PRODUCT: tooth brushing/fluoridated toothpaste over the counter 1450 ppm, interdental cleaning,fluoride rinse OTC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study to Investigate the Pharmacokinetic Comparability of Dosing Triferic AVNU IV by Continuous Infusion and IV Bolus.
Status: COMPLETED
Conditions: End Stage Renal Disease
Interventions: DRUG: Triferic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transcranial Direct-Current Stimulation (tCDS) and Robotics for Children With Hemiplegia
Status: UNKNOWN
Conditions: Cerebral Palsy|Hemiplegia
Interventions: OTHER: tDCS plus robotic training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Dupilumab in Patients With Persistent Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Dupilumab SAR231893|DRUG: Placebo|DRUG: Asthma Controller Therapies (include prednisone/prednisolone)|DRUG: Asthma Reliever Therapies
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Bioavailability and Effect of Food of BMS-986419 Immediate-release Tablet Formulation in Healthy Adult Participants
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: BMS-986419 DR Capsule|DRUG: BMS-986419 IR Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Zoledronic Acid in Preventing Osteoporosis in Patients Undergoing Donor Stem Cell Transplant
Status: COMPLETED
Conditions: Leukemia|Lymphoma|Myelodysplastic Syndromes|Osteoporosis|Ovarian Cancer
Interventions: DIETARY_SUPPLEMENT: calcium|DIETARY_SUPPLEMENT: cholecalciferol|DRUG: zoledronic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PanACEA DElpazolid Dose-finding and COmbination DEvelopment (DECODE)
Status: COMPLETED
Conditions: Infections and Infestations|Pulmonary Tuberculosis
Interventions: DRUG: Delpazolid|DRUG: Bedaquiline, Delamanid, Moxifloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Absorption-Distribution-Metabolism-Excretion (ADME) of [14C]IMP4297 to China Healthy Male Subjects
Status: UNKNOWN
Conditions: Solid Tumor
Interventions: DRUG: 14C-IMP4297
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Impacts of an Advanced Practice Physiotherapy Model of Care for Adults With a Peripheral Musculoskeletal Disorders Referred to an Orthropaedic Outpatient Clinic
Status: RECRUITING
Conditions: Musculoskeletal Disorders
Interventions: OTHER: Advanced practice physiotherapy and orthopedic surgeon management|OTHER: Orthopedic surgeon management
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of TelmisartanFor the Prevention of Acute GVHD Post Allogeneic Hematopoietic Stem Cell Transplantation
Status: TERMINATED
Conditions: GVHD
Interventions: DRUG: Telmisartan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Trial of the Effectiveness of Topical "ABH Gel" vs. Placebo in Cancer Patients With Nausea
Status: COMPLETED
Conditions: Nausea|Vomiting
Interventions: DRUG: ABH gel|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Hysterosalpingography and Comfort Theory
Status: COMPLETED
Conditions: Nursing Caries
Interventions: OTHER: Nursing Care Based on Kolcaba's Comfort Theory
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Safety, Efficacy, and Pharmacokinetics of Topical ACD440 in Healthy Volunteers
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: ACD440|DRUG: PLAC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy,Immunogenicity and Safety of COVID-19 Vaccine , Inactivated Booster Dose in Adults Aged 18 Years and Above
Status: WITHDRAWN
Conditions: COVID-19
Interventions: BIOLOGICAL: Medium-dosage COVID-19 Vaccine,Inactivated|BIOLOGICAL: High-dosage COVID-19 Vaccine,Inactivated|BIOLOGICAL: Placebo-comparator group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Iron Absorption From Regular, Biofortified and Post-harvest Fortified Pearl Millet
Status: COMPLETED
Conditions: Iron Deficiency|Biofortification
Interventions: OTHER: Regular iron|OTHER: Iron biofortified millet|OTHER: Post-harvest iron-fortifed millet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Safety of GSK Biologicals' Infanrix-IPV+HibTM Vaccine in Healthy Vietnamese Toddlers
Status: COMPLETED
Conditions: Acellular Pertussis|Haemophilus Influenzae Type b|Tetanus|Poliomyelitis|Diphtheria|Diphtheria-Tetanus-aPertussis-Poliomyelitis-Haemophilus Influenzae Type b Vaccines
Interventions: BIOLOGICAL: Infanrix-IPV+Hib™
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Estimate The Effect Of Lersivirine On The Pharmacokinetics Of Abacavir/Lamivudine In Healthy Subjects
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Abacavir/Lamivudine|DRUG: Abacavir/Lamivudine|DRUG: Lersivirine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Investigate the Absorption, Metabolism and Excretion of [14C] Anlotinib in Patients With Advanced Cancer Patients
Status: COMPLETED
Conditions: Advanced Solid Tumors
Interventions: DRUG: Anlotinib and 14C-labeled Anlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial of Percutaneous vs. Endoscopic Drainage of Suspected Klatskin Tumors
Status: TERMINATED
Conditions: Cholangiocarcinoma|Hilar Lymphadenopathy|Biliary Stricture
Interventions: PROCEDURE: PTBD|PROCEDURE: ERC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Oxybutynin for the Treatment of Urge Urinary Incontinence
Status: COMPLETED
Conditions: Urinary Incontinence, Urge
Interventions: DRUG: oxybutynin|DRUG: oxybutynin|DRUG: oxybutynin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Deep Cervical Lymphatlc-Venous Anastomosis Surgery for the Treatment of Alzheimer's Disease: A Pilot Study (DIVA Study)
Status: RECRUITING
Conditions: Alzheimer's Disease
Interventions: PROCEDURE: Deep Cervical lymphatlc-Venous Anastomosis Surgery|DRUG: Lecanemab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non-specific Effects of a Modified Measles Vaccination Schedule to Prevent Allergy and Unrelated Infection in Children
Status: RECRUITING
Conditions: Respiratory Tract Infections|Infections|Allergy|Eczema
Interventions: BIOLOGICAL: Measles-Mumps-Rubella vaccine (MMR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparative Efficiency of Three Regimen, CEFci, CEF and EC as Neoadjuvant Chemotherapy for Primary Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: 5-FU（intravenous infusion）+epirubicin+cyclophosphamide|DRUG: 5-FU（intravenous bolus）+epirubicin+cyclophosphamide|DRUG: epirubicin+cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The HOPE Trial and the SMART Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Gynecologic Cancer
Interventions: DEVICE: Fitbit Zip|OTHER: HOPE App|OTHER: Standard of Care|DEVICE: Fitbit Charge 2|OTHER: SMART Study Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effects of Ketamine and Methadone on Postoperative Pain for Laminectomy
Status: TERMINATED
Conditions: Laminectomy
Interventions: DRUG: Ketamine|DRUG: Methadone|DRUG: Ketamine + methadone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multicenter Pilot-study for the Therapy of Medulloblastoma of Adults
Status: COMPLETED
Conditions: Medulloblastoma
Interventions: DRUG: maintenance chemotherapy (vincristin, cisplatin and CCNU)|RADIATION: Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Efficacy Trial of the MindFi App for Stress, Well-being, and Sleep Quality in Working Adults
Status: COMPLETED
Conditions: Stress|Burnout
Interventions: BEHAVIORAL: MindFi app: Standard content|BEHAVIORAL: Mindfi app: Standard content without practice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of PAP on Lower Limb Explosive Force in Basketball Players in CHINA
Status: RECRUITING
Conditions: Physical Fitness
Interventions: BEHAVIORAL: PAP induced at an intensity of 70% 1RM combined with complex training|BEHAVIORAL: PAP induced at an intensity of 80% 1RM combined with complex training|BEHAVIORAL: PAP induced at an intensity of 90% 1RM combined with complex training|BEHAVIORAL: Routine warm-up combined with complex training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Injections of Botulinic Toxin in Plantar Lesions of Localized Epidermolysis Bullosa Simplex
Status: RECRUITING
Conditions: Epidermolysis Bullosa Simplex
Interventions: DRUG: Botulinic toxin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of a Motor Imagery Exercise Protocol in Patients With Fibromyalgia
Status: COMPLETED
Conditions: Fibromyalgia|Pain, Chronic|Image, Body|Psychological Distress
Interventions: OTHER: Motor Imagery physical therapy|OTHER: Conventional physical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Accelerated Continue Theta-burst Stimulation (acTBS)Treatment for Obsessive Compulsive Disease
Status: RECRUITING
Conditions: Obsessive-Compulsive Disorder|Accelerated Continue Theta-burst Stimulation|Transcranial Magnetic Stimulation|Functional Magnetic Resonance Imaging
Interventions: DEVICE: Accelerated transcranial magnetic stimulation with real coil|DEVICE: Transcranial magnetic stimulation with real coil|DEVICE: Transcranial magnetic stimulation with sham coil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Pharmacodynamics and Pharmacokinetics Study of Generic and Reference Clopidogrel Products
Status: COMPLETED
Conditions: Pharmacodynamics
Interventions: DRUG: Generic clopidogrel product Apolets®|DRUG: Original clopidogrel product Plavix®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: Effect of Inhaled Ciclesonide Versus Fluticasone Propionate in Patients With Mild to Moderate Asthma (18 to 65 y) (BY9010/M1-129)
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Ciclesonide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Back School or Brain School for Patients Undergoing Surgery for Lumbar Radiculopathy?
Status: COMPLETED
Conditions: Lumbar Radiculopathy
Interventions: BEHAVIORAL: Brain school|BEHAVIORAL: Back school
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Bioequivalence Study of Cephalexin Suspension 125
Status: COMPLETED
Conditions: Infections, Respiratory Tract
Interventions: DRUG: Cephalexin 125 mg/5ml|DRUG: Cephalexin 125 mg/5ml
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Evaluation of PHP-201 Ophthalmic Solution in Patients With Normal Tension Glaucoma
Status: COMPLETED
Conditions: Normal Tension Glaucoma
Interventions: DRUG: PHP-201 0.25% ophthalmic solution|DRUG: PHP-201 0.5% ophthalmic solution|DRUG: Placebo ophthalmic solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of cccDNA and Total HBV DNA Kinetics in Lymphocytes, Total Blood and Serum in Chronic Hepatitis B Patients Treated With Adefovir Dipivoxil and Peg Interferon Alpha 2a
Status: COMPLETED
Conditions: Chronic Hepatitis B
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Cetuximab in Combination With Chemotherapy in Patients With Recurrent and/or Metastatic Squamous Cell Carcinoma of the Head and Neck (SCCHN)
Status: COMPLETED
Conditions: Squamous Cell Carcinoma of the Head and Neck
Interventions: DRUG: Cetuximab|DRUG: Cisplatin/Carboplatin|DRUG: 5-Fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early and Midterm Outcomes of Intravascular Ultrasound (IVUS) Versus Non-IVUS Guidance in Complex Coronary Chronic Total Occlusion (CTO) Revascularization.
Status: NOT_YET_RECRUITING
Conditions: Chronic Total Occlusion of Coronary Artery
Interventions: PROCEDURE: intravascular ultrasound (IVUS)|PROCEDURE: Conventional CTO PCI (non-IVUS guided)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Study of MultiGeneAngio in Patients With Chronic Critical Limb Ischemia
Status: ACTIVE_NOT_RECRUITING
Conditions: Peripheral Arterial Disease|Peripheral Vascular Disease|Critical Limb Ischemia
Interventions: BIOLOGICAL: MultiGeneAngio|BIOLOGICAL: MultiGeneAngio
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stereotactic Radiotherapy of the Resection Cavity of Brain Metastases vs. Post-operative Whole-brain Radiotherapy
Status: COMPLETED
Conditions: Brain Metastases, Adult
Interventions: RADIATION: post-operative stereotactic radiosurgery (SRS)|RADIATION: Whole brain radiotherapy (WBRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Brief Physical Activity Intervention for Older People With Multimorbidity
Status: COMPLETED
Conditions: Chronic Conditions, Multiple|Old Age; Debility|Physical Inactivity
Interventions: BEHAVIORAL: Brief physical activity intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Smoking Reduction In Gravid Substance Use Disorders
Status: COMPLETED
Conditions: Tobacco Smoking in Mother Complicating Pregnancy|Tobacco Use Disorder|Tobacco Smoking
Interventions: DIAGNOSTIC_TEST: knowledge of expired maternal carbon monoxide and fetal carboxyhemoglobin levels
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Eosinophilic Gastrointestinal Disorders Registry
Status: RECRUITING
Conditions: Eosinophilic Esophagitis|Eosinophilic Gastroenteritis|Eosinophilic Colitis|Eosinophilic Gastrointestinal Disease
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Diaphragmatic Breathing Retraining in Heart Failure Patients: Health-Behavior Related Outcomes
Status: TERMINATED
Conditions: Dyspnea
Interventions: BEHAVIORAL: diaphragmatic breathing retraining|BEHAVIORAL: Health Promotion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of KRAS Neoantigen mRNA Vaccine (ABO2102) in Patients With KRAS -Mutated Advanced Pancreatic Cancer
Status: NOT_YET_RECRUITING
Conditions: Pancreatic Neoplasms
Interventions: DRUG: ABO2102|DRUG: Toripalimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Second-line Study of PEGPH20 and Pembro for HA High Metastatic PDAC
Status: UNKNOWN
Conditions: Pancreatic Ductal Adenocarcinoma|Pancreatic Cancer|Pancreatic Neoplasms
Interventions: DRUG: PEGPH20|BIOLOGICAL: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Trial Using Isatuximab to Overcome Platelet Transfusion Refractoriness in Human Leukocyte Antigen Allo-Immunized Patients (SuppCare 001)
Status: TERMINATED
Conditions: Platelet Refractoriness|Hematologic Malignancy
Interventions: DRUG: isatuximab 10 mg/kg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Suprachoroidal Injection of Triamcinolone Acetonide in Subjects With Macular Edema Following Non-Infectious Uveitis
Status: COMPLETED
Conditions: Uveitis|Macular Edema|Uveitis, Posterior|Uveitis, Anterior|Panuveitis|Uveitis, Intermediate
Interventions: DRUG: 4 mg CLS-TA|DRUG: 0.8 mg CLS-TA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of a New Local Anesthesia Method for Transperineal Prostate Biopsy
Status: COMPLETED
Conditions: Prostate Biopsy|Local Anesthesia
Interventions: PROCEDURE: local anesthesia of trnasperineal prostate biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Post-prostatectomy Radiation Therapy--Moderate Versus Ultra-hypofractionated (Also Known as Stereotactic Body Radiation Therapy [SBRT])
Status: RECRUITING
Conditions: Prostate Cancer
Interventions: RADIATION: Ultra-hypofractionated radiation therapy|RADIATION: Moderately Hypo-fractionated Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neoepitope-based Personalized Vaccine Approach in Pediatric Patients With Recurrent Brain Tumors
Status: WITHDRAWN
Conditions: Pediatric Brain Tumor
Interventions: BIOLOGICAL: Personalized peptide vaccine|DRUG: Poly ICLC|PROCEDURE: Peripheral blood draw
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of BPL-1357, A BPL-Inactivated, Whole-Virus, Universal Influenza Vaccine
Status: COMPLETED
Conditions: Influenza
Interventions: OTHER: IN Placebo|OTHER: IM Placebo|DRUG: BPL-1357
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Patient Reported Outcomes by Patients With Metastatic Renal Cell Carcinoma
Status: UNKNOWN
Conditions: Metastatic Renal Cell Carcinoma|Kidney Cancer|Kidney Neoplasm|Urologic Cancer|Urologic Neoplasms|Advanced Renal Cell Carcinoma
Interventions: DEVICE: Electronic patient-reported outcomes regarding symptoms and health-related quality of life
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Bone Mineral Density in Human Immunodeficiency Virus Type 1 (HIV-1)-Infected Adult Subjects Switching From a Tenofovir Regimen to a Dolutegravir Plus Rilpivirine Regimen
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Subjects do not receive study medication in this study 202094
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevention of Syncope Trial 6 - Atomoxetine in Vasovagal Syncope
Status: COMPLETED
Conditions: Vasovagal Syncope
Interventions: DRUG: Atomoxetine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Growth Factor to Prevent Oral Mucositis in Patients With Hematologic Cancer
Status: COMPLETED
Conditions: Drug/Agent Toxicity by Tissue/Organ|Leukemia|Lymphoma|Multiple Myeloma and Plasma Cell Neoplasm|Oral Complications|Radiation Toxicity
Interventions: BIOLOGICAL: filgrastim|BIOLOGICAL: palifermin|DRUG: cyclophosphamide|DRUG: etoposide|DRUG: ifosfamide|PROCEDURE: quality-of-life assessment|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Atazanavir (BMS-232632) in Combination With Ritonavir or Saquinavir, and Lopinavir/Ritonavir, Each With Tenofovir and a Nucleoside in Subjects With HIV
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Atazanavir + ritonavir + tenofovir + nucleoside|DRUG: Atazanavir + saquinavir + tenofovir + nucleoside|DRUG: Lopinavir/ritonavir + tenofovir + nucleoside
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of MOXR0916 in Combination With Atezolizumab Versus Atezolizumab Alone in Participants With Untreated Locally Advanced or Metastatic Urothelial Carcinoma Who Are Ineligible for Cisplatin-Based Therapy
Status: TERMINATED
Conditions: Urothelial Carcinoma
Interventions: DRUG: MOXR0916|DRUG: Atezolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Sensory Re-education of the Hand With a Sensor Glove Model
Status: COMPLETED
Conditions: Peripheral Nerve Injuries
Interventions: OTHER: Early sensory re-education of the hand with a sensor glove model
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Safety, Tolerability and Pharmacokinetics of ZX-7101A and the Food Effect in Healthy Volunteers
Status: COMPLETED
Conditions: Safety Issues|Tolerance|Pharmacokinetics|Food Effect
Interventions: DRUG: ZX-7101A|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: TALAVE: Induction Talazoparib Followed by Combination of Talazoparib and Avelumab in Advanced Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Talazoparib|DRUG: Avelumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness and Safety of STYLAGE® M LIDOCAINE Versus STYLAGE® M in Filling Nasolabial Folds
Status: COMPLETED
Conditions: Aging
Interventions: DEVICE: STYLAGE® M Lidocaïne|DEVICE: STYLAGE® M
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Single-Arm Study Evaluating Use of the CORA Catheters for the Crossing of Coronary Chronic Total Occlusions
Status: NOT_YET_RECRUITING
Conditions: Coronary Occlusion
Interventions: DEVICE: coraFlex Catheter|DEVICE: coraForce Catheter|DEVICE: coraCross Catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Re-irradiation at Relapse Versus RT and Multiple Elective rt Courses
Status: ACTIVE_NOT_RECRUITING
Conditions: Diffuse Intrinsic Pontine Glioma
Interventions: DRUG: Nimotuzumab|DRUG: Vinorelbine|OTHER: Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Docetaxel +/- Suramin in 2nd Line Advanced Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Carcinoma, Non Small Cell Lung
Interventions: DRUG: Docetaxel|DRUG: Suramin|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hygienic Socks With Antifungal Agent-loaded Microcapsules for Patients With Tinea Pedis
Status: COMPLETED
Conditions: Tinea Pedis
Interventions: DRUG: Anti-fungal agent (Clotrimazole) loaded microcapsules|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: T-cell and B-cell Depletion in Allogeneic Peripheral Blood Stem Cell Transplantation
Status: TERMINATED
Conditions: Leukemia, Myeloid|Leukemia, Lymphocytic|Myelodysplastic Syndrome|Leukemia, Myeloid, Chronic|Lymphoma
Interventions: PROCEDURE: T-cell and B-cell depletion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 68Ga-PSMA-R2 in Patients With Biochemical Relapse (BR) and Metastatic Prostate Cancer (mPCa)
Status: COMPLETED
Conditions: Prostate Cancer Metastatic
Interventions: DRUG: [68Ga]-PSMA-R2
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Herceptin (Trastuzumab) in Treating Women With Human Epidermal Growth Factor Receptor (HER) 2-Positive Primary Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Herceptin|DRUG: Herceptin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of ctDNA Guided Change in Tx for Refractory Minimal Residual Disease in Colon Adenocarcinomas
Status: RECRUITING
Conditions: Colon Adenocarcinoma|Colorectal Cancer
Interventions: DRUG: TAS-102|DRUG: Irinotecan|COMBINATION_PRODUCT: Standard Treatment|DIAGNOSTIC_TEST: Signatera MRD ctDNA Assay
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Patient Satisfaction and Safety Outcomes After Enrollment in a Same-Day (SD) Percutaneous Coronary Intervention Program
Status: COMPLETED
Conditions: To Evaluate Clinical Outcomes, Safety, and Satisfaction of Patients Who Have Participated in a Same Day Outpatient Percutaneous Coronary Artery Intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Forodesine (BCX-1777) in Treating Patients With Refractory Stage IIA, Stage IIB, Stage III, Stage IVA, or Stage IVB Cutaneous T-Cell Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: DRUG: forodesine hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 802NP301 Efficacy and Safety Study of BIIB074 in Participants With Trigeminal Neuralgia
Status: WITHDRAWN
Conditions: Trigeminal Neuralgia
Interventions: DRUG: BIIB074|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Denosumab (AMG 162) in Bisphosphonate Naive Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer|Metastases|Bone Metastases in Subjects With Advanced Breast Cancer
Interventions: BIOLOGICAL: Denosumab|DRUG: IV Bisphosphonates
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of a CarePartner-Integrated Telehealth Rehabilitation Program for Persons With Stroke
Status: COMPLETED
Conditions: Stroke
Interventions: BEHAVIORAL: CARE-CITE Education Program|BEHAVIORAL: Traditional Education|BEHAVIORAL: Constraint-Induced Movement Therapy (CIMT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pressure-enabled Delivery in Radioembolization (TriNav Study)
Status: RECRUITING
Conditions: Liver Cancer|Hepatocellular Carcinoma|Metastatic Colorectal Cancer
Interventions: DEVICE: Standard microcatheter|DEVICE: PEDD device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC