pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Microneedle Pretreatment as a Strategy to Improve the Effectiveness of Topical Anesthetics Formulations
Status: COMPLETED
Conditions: Oral Cavity Disease
Interventions: DRUG: Topical Anesthetic|DRUG: Local anesthetic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Etanercept and Gemcitabine in Patients With Advanced, Chemotherapy Naive Pancreatic Adenocarcinoma
Status: COMPLETED
Conditions: Pancreatic Neoplasms|Adenocarcinoma
Interventions: DRUG: Gemcitabine|DRUG: Etanercept
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SMOOTH - Blood Pressure Control in Diabetic/Obese Patients
Status: COMPLETED
Conditions: Hypertension|Diabetes Mellitus, Type 2
Interventions: DRUG: telmisartan combined with hydrochlorothiazide (80/12.5 mg)|DRUG: valsartan combined with hydrochlorothiazide (160/12.5mg)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Blueberry Powder Supplementation on Cardiovascular Risk Factors in Subjects With the Metabolic Syndrome
Status: WITHDRAWN
Conditions: Metabolic Syndrome
Interventions: DIETARY_SUPPLEMENT: Blueberry Powder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Capecitabine (NX) Versus Docetaxel Plus Capecitabine (TX) as 1-line Chemotherapy on Metastatic Breast Cancer (MBC)
Status: UNKNOWN
Conditions: Carcinoma, Invasive Ductal, Breast
Interventions: DRUG: Vinorelbine plus Capecitabine for 6 cycles, followed by Capecitabine|DRUG: Docetaxel plus Capecitabine for 6 cycles, followed by Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Validation of An Optimized Multi-Target Stool DNA (Mt-sDNA 2.0) Test, for Colorectal Cancer Screening "BLUE-C"
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DIAGNOSTIC_TEST: mt-sDNA 2.0 screening test|DIAGNOSTIC_TEST: FIT test|PROCEDURE: Colonoscopy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: LBH589 Plus Decitabine for Myelodysplastic Syndromes (MDS) or Acute Myeloid Leukemia (AML)
Status: COMPLETED
Conditions: Leukemia, Myeloid, Acute|Myelodysplastic Syndromes
Interventions: DRUG: LBH589|DRUG: Decitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Additional Value of Noninvasive Ventilation Next to Rehabilitation in Hypercapnic COPD Patients
Status: UNKNOWN
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DEVICE: Noninvasive positive pressure ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Promoting Repeat Blood Donation Through Social Media Among First-time Donors in a Peruvian Blood Bank
Status: COMPLETED
Conditions: Blood Donors
Interventions: OTHER: Social Media Publications
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Randomised, Phase 3 Non-inferiority Study of DOR/3TC/TDF Compared to DTG/TAF/FTC in Participants Infected With HIV-1 Starting First-line Antiretroviral Therapy
Status: RECRUITING
Conditions: HIV-1-infection
Interventions: DRUG: Delstrigo|DRUG: KOCITAF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anti-PD-1/PD-L1 Antibodies Plus Anti-VEGF Antibody Treatment in Patients With Advanced-Stage HCC
Status: RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Anti-PD-1/PD-L1 antibodies|DRUG: Anti-VEGF
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Recolonisation of Bacteria in Hands and Possible Bacterial Leakage From Glove Cuff in Cardiac Surgery
Status: COMPLETED
Conditions: Bacterial Growth
Interventions: PROCEDURE: Surgical hand disinfection.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: A Study to Investigate the Efficacy, Safety, and Tolerability of Repeat Doses of Inhaled GSK2269557 in Adults With Persistent, Uncontrolled Asthma
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: GSK2269557 DPI|DRUG: Placebo DPI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study for Comparative Assessment of Efficacy and Safety of Angal S, Topical Spray and ANTI-ANGIN® FORMULA, Topical Metered Spray in Treatment of Patients With Uncomplicated Acute Infectious and Inflammatory Diseases of the Pharynx, Accompanied by a Sore Throat
Status: COMPLETED
Conditions: Sore Throat
Interventions: DRUG: Angal S, topical spray [Menthol]|DRUG: ANTI-ANGIN® FORMULA, topical metered spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Aspects of 25-mg Estradiol Pellet in Climacteric Women
Status: ACTIVE_NOT_RECRUITING
Conditions: Climacteric Syndrome|Menopause|Hypoestrogenism
Interventions: DRUG: s.c 25 mg estradiol pellet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Novel Flower-type Covered Stent and Conventional Covered Stent
Status: UNKNOWN
Conditions: Malignant Biliary Obstruction
Interventions: DEVICE: Endoscopic Retrograde CholangioPancreatography(ERCP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Stavanger UncomPlicatEd Elective PCI Same DaY Discharge Study (SPEEDY Study)
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: PROCEDURE: same day discharge
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Safety and Tolerability of FITC-Adalimumab Administration During Confocal Laser Endomicroscopy of the Gut
Status: COMPLETED
Conditions: Crohn's Disease
Interventions: DRUG: FITC-Adalimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of Carbon-14-Labelled [14C] LY3871801 in Healthy Male Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: [14C]-LY3871801
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Diagnostic Genicular Nerve Block Prior to Radiofrequency Ablation for Knee Osteoarthritis Pain
Status: COMPLETED
Conditions: Osteoarthritis, Knee|Pain|Nerve; Lesion
Interventions: PROCEDURE: genicular nerve diagnostic block with lidocaine (local anesthetic)|PROCEDURE: genicular nerve radiofrequency ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Unsupported Arm Exercise and Breathing Strategy in Patients With Chronic Obstructive Pulmonary Disease
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: BEHAVIORAL: breathing strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigating a Marijuana-based Compound as a Treatment for Anxiety in Autistic Adults
Status: NOT_YET_RECRUITING
Conditions: Autism Spectrum Disorder|Anxiety
Interventions: DRUG: MB-IMP|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Different Early Intensive Therapies on Long-term β-cell Function
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: CSII|DRUG: CSII, Metformin, Pioglitazone|DRUG: CSII, Sitagliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Injections of Autologous PRP in Women With Primary Ovarian Insufficiency
Status: COMPLETED
Conditions: Primary Ovarian Insufficiency|Premature Menopause
Interventions: PROCEDURE: A-PRP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Everolimus in de Novo Liver Transplantation: a Multicentre Randomized Study
Status: UNKNOWN
Conditions: Liver Failure|Liver Diseases|Liver Cirrhosis|Liver Neoplasms
Interventions: DRUG: Everolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Evaluate the Efficacy and Safety of Neuronox and Botox With Moderate to Severe Glabellar Lines
Status: COMPLETED
Conditions: Glabellar Lines
Interventions: DRUG: Neuronox|DRUG: Botox
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study of Perioperative Nivolumab and Paricalcitol to Target the Microenvironment in Resectable Pancreatic Cancer
Status: TERMINATED
Conditions: Pancreatic Cancer
Interventions: DRUG: Nivolumab|DRUG: Nab-Paclitaxel|DRUG: Gemcitabine|DRUG: Paricalcitol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of LY3437943 in Japanese Participants With Type 2 Diabetes Mellitus (T2DM)
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: LY3437943|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Clinical Study to Evaluate the Anti-Sensitivity Effect of a Calcium Sodium Phosphosilicate Toothpaste in a Population of Dentin Hypersensitivity Sufferers
Status: ACTIVE_NOT_RECRUITING
Conditions: Dentin Sensitivity
Interventions: DRUG: CSPS toothpaste|DRUG: Regular fluoride toothpaste (Crest Cavity Protection)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Short Femoral Stem in Total Hip Arthroplasty
Status: WITHDRAWN
Conditions: Osteoarthritis, Hip
Interventions: DEVICE: Short stem hip arthroplasty (SHA)|DEVICE: Total hip arthroplasty (THA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Weighted Blanket Use to Reduce Anxiety in Oncology Patients
Status: RECRUITING
Conditions: Hematopoietic and Lymphoid Cell Neoplasm|Malignant Solid Neoplasm
Interventions: OTHER: Best Practice|OTHER: Supportive Care|OTHER: Survey Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Trial of Enzastaurin and Bevacizumab in Participants With Recurrent Malignant Gliomas
Status: COMPLETED
Conditions: Recurrent Glioblastoma
Interventions: DRUG: enzastaurin|DRUG: bevacizumab|DRUG: Enzyme-inducing antiepileptic drugs (EIAED)|DRUG: Non-enzyme inducing antiepileptic drugs (NEIAED)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combined Medial and Caudal Approach for Right Hemicolectomy
Status: COMPLETED
Conditions: Colon Cancer
Interventions: PROCEDURE: combined medial and caudal approach right hemicolectomy open and laparoscopic
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vaccine Therapy in Treating Patients With Recurrent Glioblastoma
Status: COMPLETED
Conditions: Giant Cell Glioblastoma|Recurrent Glioblastoma|Recurrent Gliosarcoma
Interventions: OTHER: Laboratory Biomarker Analysis|BIOLOGICAL: Malignant Glioma Tumor Lysate-Pulsed Autologous Dendritic Cell Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Dual Trigger (GnRH Agonist + hCG) for Final Maturation in Oocyte Donors With History of a Previous Cycle With Suboptimal Response to GnRH Agonist Only Trigger
Status: RECRUITING
Conditions: Ovarian Stimulation|Human Chorionic Gonadotropin|Oocyte Donors
Interventions: DRUG: Dual trigger (human chorionic gonadotropin plus GnRH-agonist)|DRUG: GnRH-agonist only trigger
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Serum Progesterone on the Day of Thawed Embryo Transfer and Pregnancy Rate After an Artificial Endometrial Preparation
Status: COMPLETED
Conditions: IVF
Interventions: DRUG: Progesterone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: A Phase 3 Study With P2B001 in Subjects With Early Parkinson's
Status: COMPLETED
Conditions: Parkinson Disease|Early Parkinson's Disease
Interventions: DRUG: P2B001 0.6/0.75 mg|DRUG: Rasagiline 0.75 mg|DRUG: Pramipexole 0.6 mg|DRUG: Marketed Pramipexole ER
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Trial of Continuous Portable Postoperative Hemodynamic And Saturation Monitoring On Hospital Wards
Status: COMPLETED
Conditions: Hemodynamic Instability|Respiratory Complications of Care
Interventions: DEVICE: ViSi device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Palonosetron Versus Combination of Palonosetron and Dexamethasone for Preventing Postoperative Vomiting in Patients Receiving Fentanyl by Patient-controlled Analgesia After Minor Orthopedic Surgery
Status: COMPLETED
Conditions: Orthopedic Surgery
Interventions: DRUG: palonosetron|DRUG: palonosetron with dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of the Physiopathological Phenomena and the Haemodynamic and Cerebral Metabolic Effects From Semi-seated Position to Lying Position in Patients With Brain Trauma
Status: UNKNOWN
Conditions: Traumatic Brain Injury
Interventions: OTHER: Change from semi-seated position to supine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Total Knee Arthroplasty Combined With Psychological Intervention for Patients With Psychological Disorders
Status: COMPLETED
Conditions: Osteoarthritis, Knee|Psychological Disorder|Psychological Intervention|Satisfaction|Total Knee Arthroplasty
Interventions: OTHER: Psychological Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of SyntheCelTM Dura Replacement to Other Dura Replacements
Status: COMPLETED
Conditions: Cranial Dura Repair
Interventions: DEVICE: SyntheCel|DEVICE: Other FDA cleared dura replacements
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Fluticasone Propionate Associated With Salmeterol Using Inhalation Chamber Versus Placebo to Improve the Respiratory Function in Children Over Six Years of Age Who Underwent Allogeneic Hematopoietic Stem Cell Transplantation With a Decline of FEV1 ≥10% From Pre Transplantation
Status: TERMINATED
Conditions: Stem Cell Transplant Complications|Respiratory Disease|Bronchiolitis Obliterans
Interventions: DRUG: Seretide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Relacorilant in Combination With Nab-Paclitaxel in Advanced, Platinum-Resistant, High-Grade Epithelial Ovarian, Primary Peritoneal, or Fallopian-Tube Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Ovarian Neoplasm|Fallopian Tube Neoplasms|Peritoneal Neoplasms
Interventions: DRUG: Nab-paclitaxel 80 mg/m^2|DRUG: Relacorilant 150 mg once daily (QD)|DRUG: Nab-paclitaxel 100 mg/m^2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Emotion Endophenotypes in Schizophrenia
Status: UNKNOWN
Conditions: Schizophrenia
Interventions: OTHER: MRI (Magnetic resonance imaging)|GENETIC: Polymorphism (SNP in DNA)|GENETIC: quantitative measures of mRNA|OTHER: Neuropsychological assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Effect of Atracurium and Rocuronium on the State and Response Entropy During Isoflurane Anesthesia
Status: COMPLETED
Conditions: Entropy Device and How Will Muscle Relaxants Affect it
Interventions: DRUG: Atracurium Besylate|DRUG: Rocuronium Bromide|DEVICE: Entropy|DEVICE: train of four
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Erector Spinae Plane Block and Subcostal Transverse Abdominis Plane Block in Laparoscopic Cholecystectomy
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: OTHER: Standard Pain Followup and Monitorization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Prevention and Treatment With Calcifediol of COVID-19 Induced Acute Respiratory Syndrome
Status: COMPLETED
Conditions: SARS-CoV 2|COVID19|SARS (Severe Acute Respiratory Syndrome)|Cytokine Release Syndrome|Cytokine Storm
Interventions: DRUG: BAT + Calcifediol|DRUG: BAT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Analgesic Efficacy of Nerve Blocks on Otoplastic Surgery
Status: UNKNOWN
Conditions: Microtia|Microtia, Congenital
Interventions: PROCEDURE: intercostal nerve block under direct vision|PROCEDURE: intercostal nerve block under ultrasound guidance|PROCEDURE: paravertebral block under ultrasound guidance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of 3D Printed Myoelectric Prosthetic Devices in Children With Upper Congenital Limb Deficiency
Status: NOT_YET_RECRUITING
Conditions: Limb Deformities, Congenital|Upper Extremity Deformities, Congenital|Congenital Abnormalities
Interventions: DEVICE: 3D myoelectric prosthetic device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multiomics and Imaging-based Assessment of Vulnerable Coronary Plaques in Acute Coronary Syndromes
Status: COMPLETED
Conditions: Coronary Stenosis|Acute Coronary Syndrome|Acute Myocardial Infarction|Atheromatous Plaques|Atherosclerosis|Unstable Angina|Non-ST Elevation Myocardial Infarction
Interventions: DIAGNOSTIC_TEST: cardiac imaging tests
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effects of Antioxidants in Blueberry Powder on Inflammation Induced by a Single High Fat Meal.
Status: COMPLETED
Conditions: Inflammation
Interventions: OTHER: Breakfast meal with placebo powder|OTHER: Breakfast meal with 2 serving equivalents of blueberries|OTHER: Breakfast meal with 4 serving equivalents of blueberries
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effectiveness of Autonomic Nervous System, Sleep Quality, and Immune Regulation for Shift Nurses Practicing Alternative Nostril Breathing
Status: UNKNOWN
Conditions: Shift Nurses
Interventions: BEHAVIORAL: Alternative nostril breathing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Aflibercept for Retinopathy of Prematurity - Intravitreal Injection Versus Laser Therapy
Status: COMPLETED
Conditions: Retinopathy of Prematurity (ROP)
Interventions: DRUG: Eylea (Aflibercept, BAY86-5321)|PROCEDURE: Laser photocoagulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Amantadine Sulphate Usage in Spine Deformities Corrective Surgeries Patients
Status: COMPLETED
Conditions: Spinal Curvatures
Interventions: DRUG: Group A amantadine sulfate|OTHER: Group B ringer lactate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Cetuximab, Paclitaxel, Carboplatin & Radiation for Esoph, Gastroesoph & Gastric Cancer
Status: COMPLETED
Conditions: Esophageal Cancer|Gastric Cancer
Interventions: DRUG: Cetuximab,Paclitaxel, Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Individually Tailored Web-Based Program to Improve Blood Pressure Control
Status: COMPLETED
Conditions: Hypertension
Interventions: BEHAVIORAL: Web-Based Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Blood Pressure Interaction Between Sildenafil and Sublingual Glyceryl Trinitrate (GTN) in Men With Angina
Status: COMPLETED
Conditions: Angina Pectoris
Interventions: DRUG: Sildenafil citrate|DRUG: Glyceryl trinitrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Vitamin D Supplementation on Calcium Excretion in Thalassemia: a Dose Response Study
Status: UNKNOWN
Conditions: Thalassemia Major
Interventions: DRUG: Vitamin D3|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy of Artesunate + Amodiaquine Versus Artemether-lumefantrine for Falciparum Malaria in Zanzibar, 2005
Status: COMPLETED
Conditions: Plasmodium Falciparum Malaria
Interventions: DRUG: Artemether-lumefantrine|DRUG: Artesunate + Amodiaquine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of Rotavirus (Bio Farma) Vaccine in Adults, Children & Neonates
Status: COMPLETED
Conditions: Safety Issues
Interventions: BIOLOGICAL: Rotavirus (Bio Farma) Vaccine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Itacitinib + Everolimus in Hodgkin Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Classical Hodgkin Lymphoma
Interventions: DRUG: Itacitinib|DRUG: Everolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of a Personalized Maintenance Therapy With the Standard Treatment in Pemphigus
Status: NOT_YET_RECRUITING
Conditions: Pemphigus|Dermatologic Disease
Interventions: DRUG: RiTUXimab Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of BRIZO on Lower Urinary Tract Symptoms (LUTS) Related to Benign Prostatic Hypertrophy (BPH)
Status: UNKNOWN
Conditions: BPH Without Urinary Obstruction and Other Lower Urinary Tract Symptoms (LUTS)
Interventions: DIETARY_SUPPLEMENT: BRIZO|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: SARS-Cov-2 (COVID-19) Nasal Pharyngeal and Oral Pharyngeal Wash (SNOW) Trial
Status: RECRUITING
Conditions: Covid19|SARS-CoV Infection
Interventions: COMBINATION_PRODUCT: Shampoo and saline|COMBINATION_PRODUCT: Saline and Listerine|COMBINATION_PRODUCT: Shampoo and Listerine|COMBINATION_PRODUCT: Saline and Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cultural Adaptation of a Behavioral Intervention for Latino Caregivers
Status: RECRUITING
Conditions: Alzheimer Disease|Dementia
Interventions: BEHAVIORAL: STAR-C Virtual Training and Follow-up (STAR-VTF)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Feasibility Trial for Inhibitory-Control Training to Reduce Cocaine Use
Status: COMPLETED
Conditions: Cocaine Use Disorder
Interventions: BEHAVIORAL: Active Inhibitory Control Training|BEHAVIORAL: Neutral Inhibitory Control Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Interest of a Weekly Consultation by a Medical Electro Radiology Manipulator (MERM) in Addition to the Follow-up by the Radiotherapist to Improve the Collection of Radio-induced Toxicities in Patients Undergoing Proton Therapy
Status: RECRUITING
Conditions: Paramedical Consultation|Radiotherapy|Proton Therapy|Brain Tumor
Interventions: OTHER: Consultation with Manipulator in Medical Radiology and a radiotherapist|OTHER: Consultation with a radiotherapist
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Brief Motivational Interviewing to Reduce Child Body Mass Index
Status: COMPLETED
Conditions: Childhood Obesity
Interventions: BEHAVIORAL: Standard Care|BEHAVIORAL: Moderate Dose Motivational Interviewing|BEHAVIORAL: Higher Dose Motivational Interviewing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Treatment of Children With Cerebral Palsy With Autologous Umbilical Cord Blood, a Pilot Study
Status: RECRUITING
Conditions: Cerebral Palsy
Interventions: OTHER: Autologous umbilical cord blood transfusion|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: GM-CSF and Combination Chemotherapy in Treating Patients Who Are Undergoing Surgery for Stage II or Stage III Colon Cancer
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: BIOLOGICAL: sargramostim|DRUG: fluorouracil|DRUG: leucovorin calcium|DRUG: oxaliplatin|PROCEDURE: adjuvant therapy|PROCEDURE: conventional surgery|PROCEDURE: neoadjuvant therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of COVID-19 on Cavernous Smooth Muscle
Status: COMPLETED
Conditions: Erectile Dysfunction Due to Diseases Classified Elsewhere|Covid19
Interventions: DIAGNOSTIC_TEST: corpus cavernosum electromyography
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Determining the Specificity of High Definition Electrical Brain Stimulation Using Simultaneous Magnetoencephalography
Status: COMPLETED
Conditions: Real HD-tDCS|Sham HD-tDCS|Visual Task|Motor Task|Auditory Task|Working Memory Task
Interventions: DEVICE: HD-tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Visual Perturbation Training to Reduce Fall Risk in People With Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson Disease|Vestibular Disorder|Gait|Falling
Interventions: OTHER: Visual perturbation treadmill training|OTHER: Regular treadmill training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Calcium, Vitamin D and Metformin to Treat Insulin Resistance in Obese African American Adolescent Females
Status: WITHDRAWN
Conditions: Insulin Resistance|Insulin Sensitivity|Obesity|Vitamin D Deficiency
Interventions: DRUG: Calcium and Vit D|DRUG: Metformin, Vit D and Calcium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anti-vasculaR Endothelial Growth Factor plUs Anti-angiopoietin 2 in Fixed comBination therapY: Evaluation for the Treatment of Diabetic Macular Edema
Status: COMPLETED
Conditions: Diabetic Macular Edema
Interventions: DRUG: REGN910-3|DRUG: Intravitreal Aflibercept Injection (IAI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study on the Use of Acupuncture for Postpartum Depression
Status: COMPLETED
Conditions: Post-partum Depression
Interventions: PROCEDURE: Active acupuncture|PROCEDURE: Placebo acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Long Term Open-label Study Evaluating Safety of Diacerein 1% Ointment Topical Formulation in Subjects With Epidermolysis Bullosa Simplex
Status: COMPLETED
Conditions: Epidermolysis Bullosa|Epidermolysis Bullosa Simplex
Interventions: DRUG: diacerein 1% ointment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Herceptin for Ductal Carcinoma In Situ of the Breast
Status: COMPLETED
Conditions: Ductal Carcinoma In Situ
Interventions: DRUG: Herceptin (Trastuzumab)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Baby Smell Visual Stimulus Program Cortical and Breast Oxygenation Milk Amount Mother-Infant Attachment
Status: COMPLETED
Conditions: Cesarean Delivery Affecting Fetus|Preterm Labor
Interventions: BEHAVIORAL: Olfactory stimulation|BEHAVIORAL: Visual stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Randomized Comparison of Catheter-based Strategies for Interventional Access Site Closure During Transfemoral Transcatheter Aortic Valve Implantation
Status: COMPLETED
Conditions: Aortic Valve Stenosis
Interventions: DEVICE: Manta|DEVICE: ProGlide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mild Versus Conventional Ovarian Stimulation for Poor Responders Undergoing In Vitro Fertilisation
Status: COMPLETED
Conditions: Infertility
Interventions: PROCEDURE: mild ovarian stimulation|PROCEDURE: conventional ovarian stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Study Evaluating the Efficacy and Safety of OK-101 in Subjects With Dry Eye Disease
Status: COMPLETED
Conditions: Dry Eye Disease
Interventions: DRUG: OK-101|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Stereotactic Body Radiation Therapy (SBRT) vs Trans-Arterial Chemoembolization (TACE) as Bridge to Transplant
Status: TERMINATED
Conditions: Hepatocellular Carcinoma|HCC
Interventions: RADIATION: Stereotactic Body Radiation Therapy (SBRT)|PROCEDURE: Trans-Arterial Chemoembolization (TACE)|DRUG: Doxorubin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transplantation of Tissue Cultured Human Amniotic Epithelial Cells Onto Damaged Ocular Surfaces
Status: WITHDRAWN
Conditions: Corneal Epithelial Dystrophy
Interventions: PROCEDURE: Transplantation of Tissue-Cultured Human Amniotic Epithelial Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Eyetronix Flicker Glasses to the Treatment of Anisometropic Amblyopia
Status: UNKNOWN
Conditions: Amblyopia, Anisometropic
Interventions: DEVICE: EFG group|DEVICE: Patching group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: O-ARM Stereotactic Imaging in Deep Brain Stimulation for Parkinson's Disease
Status: RECRUITING
Conditions: Parkinson Disease
Interventions: PROCEDURE: O-Arm Stereotactic imaging|PROCEDURE: Standard Stereotactic imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: FRIEND: Fibroids and Unexplained Infertility Treatment With Epigallocatechin Gallate; A Natural CompounD in Green Tea
Status: RECRUITING
Conditions: Leiomyoma, Uterine
Interventions: DRUG: Green Tea Extract|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Reeducation of Chronic Achilles Tendinopathy by Wearing Shoes Inclined Versus Reeducation by Kinesitherapy
Status: TERMINATED
Conditions: Tendinopathy|Rupture of Achilles Tendon|Chronic Disease
Interventions: DEVICE: 8° incline shoe|OTHER: kinesitherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Anti-CD3 mAb Treatment of Recent Onset Type 1 Diabetes
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus
Interventions: DRUG: mAb hOKT3gamma1(Ala-Ala), Teplizumab|DRUG: Placebo Arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Expiratory Muscle Strength Training (EMST) in Neuromuscular Disorders
Status: UNKNOWN
Conditions: Oculopharyngeal Muscular Dystrophy|Muscular Dystrophies|Myopathy; Hereditary
Interventions: DEVICE: Expiratory muscle strength therapy (EMST150, Aspire LLC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nutrition and Prostate Cancer
Status: TERMINATED
Conditions: Prostate Cancer
Interventions: DRUG: Fermented Soy|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Triple Therapy - PDT Plus IVD and Intravitreal Ranibizumab Versus Lucentis Monotherapy to Treat Age-Related Macular Degeneration
Status: COMPLETED
Conditions: Age Related Macular Degeneration
Interventions: DRUG: ranibizumab, dexamethasone and verteporfin|DRUG: Ranibizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study of the Pharmacokinetics and Safety of BCD-263 and Opdivo® as Monotherapy in Subjects With Advanced Melanoma of the Skin
Status: RECRUITING
Conditions: Advanced Melanoma
Interventions: DRUG: BCD-263|DRUG: Opdivo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: ON-Q Pump Infusion of Ketorolac and Ropivacaine at the Wound Site for Postoperative Pain Management
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: Ketorolac|DRUG: Ketorolac and Ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Reactogenicity of DTPa-HBV-IPV/Hib, Compared to DTPa-HBV-IPV and Hib Administered Separately
Status: COMPLETED
Conditions: Hepatitis B|Diphtheria|Haemophilus Influenzae Type b (Hib)|Poliomyelitis|Pertussis|Tetanus
Interventions: BIOLOGICAL: DTPa-HBV-IPV/Hib (Infanrix hexa™)|BIOLOGICAL: DTPa-HBV-IPV (Infanrix penta™)|BIOLOGICAL: Hib (Hiberix™)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Erbitux Combined With Chemo-radiotherapy in Esophageal Squamous Cell Carcinoma
Status: COMPLETED
Conditions: Esophageal Cancer
Interventions: DRUG: cetuximab (Erbitux)|DRUG: Paclitaxel|DRUG: Cisplatin|RADIATION: Radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of KN510, KN713
Status: RECRUITING
Conditions: Advanced Solid Tumors
Interventions: DRUG: KN510 60mg/day + KN713 60mg/day|DRUG: KN510 120mg/day + KN713 60mg/day|DRUG: KN510 120mg/day + KN713 90mg/day|DRUG: KN510 120mg/day + KN713 120mg/day
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anemia Studies in Chronic Kidney Disease (CKD): Erythropoiesis Via a Novel Prolyl Hydroxylase Inhibitor (PHI) Daprodustat-in Incident Dialysis (ASCEND-ID)
Status: COMPLETED
Conditions: Anaemia
Interventions: DRUG: Daprodustat|DRUG: Darbepoetin alfa|DRUG: Iron therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: IBD-Sleep: A Pilot Study Looking at Changes in Sleep Timing and IBD Symptoms
Status: RECRUITING
Conditions: Inflammatory Bowel Diseases|Ulcerative Colitis|Crohn Disease
Interventions: DEVICE: Morning light treatment|BEHAVIORAL: Treatment-as-usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Pharmacokinetics of Firsocostat or Fenofibrate in Adults With Normal and Impaired Hepatic Function
Status: COMPLETED
Conditions: Nonalcoholic Steatohepatitis (NASH)
Interventions: DRUG: Firsocostat|DRUG: Fenofibrate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety, Tolerability, and Efficacy of Escalating Doses of BMS-986463 in Participants With Select Advanced Malignant Tumors.
Status: RECRUITING
Conditions: High-grade Serous Ovarian Carcinoma (HGSOC)|Uterine Serous Carcinoma (USC)|Non-small Cell Lung Cancer (NSCLC)
Interventions: DRUG: BMS-986463
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Drug-Drug Interaction Study to Evaluate the Effects of Ecopipam on the Pharmacokinetics of Multiple Substrates for Drug Metabolism and Transport
Status: COMPLETED
Conditions: Drug Interaction
Interventions: DRUG: Ecopipam|COMBINATION_PRODUCT: Cohort 1 Probe Substrate Cocktail|DRUG: Cohort 2 Probe Substrate|COMBINATION_PRODUCT: Cohort 3 Probe Substrate Cocktail
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Addition of Mannitol to Bupivacaine on IANB Success and Post-endodontic Pain
Status: COMPLETED
Conditions: Irreversible Pulpitis
Interventions: DRUG: bupivacaine plus mannitol|DRUG: bupivacaine alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Sham Feeding on Small Bowel Transit Time in Patients Undergoing Capsule Endoscopy
Status: COMPLETED
Conditions: Slow Transit
Interventions: OTHER: Sham Feeding of Bacon Bits|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Dietary Intervention Trial Targeting Metabolic Syndrome After Kidney Transplantation
Status: UNKNOWN
Conditions: Kidney Transplant; Complications
Interventions: OTHER: high-protein, carbohydrate-reduced diet|OTHER: Dutch Nutritional Guidelines
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of ZN-c3 in Women With Recurrent or Persistent Uterine Serous Carcinoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Uterine Serous Carcinoma
Interventions: DRUG: ZN-c3
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Annovera™ and Tampon Co-Usage on the Pharmacokinetics of Segesterone Acetate and Ethinyl Estradiol
Status: COMPLETED
Conditions: Contraception
Interventions: DRUG: Segesterone Acetate and Ethinyl Estradiol|OTHER: Tampon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effect of Food on the Level of Circulating Elafibranor in Healthy Participants After Intake of a Single Tablet
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DRUG: elafibranor|DRUG: elafibranor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Bioavailability of Vitamin D in Children and Adolescents With Crohn's Disease
Status: COMPLETED
Conditions: Crohn's Disease
Interventions: DRUG: Vitamin D3 3000 UI daily|DRUG: Vitamin D3 4000 UI daily
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cetylated Fatty Acid for Reducing Pain After TKA
Status: RECRUITING
Conditions: Postoperative Pain|Postoperative Inflammation
Interventions: DRUG: cetylated fatty acid|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Auryzon Devices in the Optimization of Ear and Nose Reconstruction Procedures
Status: SUSPENDED
Conditions: Ear Deformities, Acquired|Ear; Deformity, Congenital|Microtia|Nose Deformity|Nose Deformities, Acquired|Nose; Deformity, Congenital|Nose; Deformity, Congenital, Bent or Squashed|Nose; Deformity, Syphilitic, Congenital|Nose; Deformity, Bone (Nose Cartilage)|Nose; Deformity, Septum, Congenital|Nose; Deformity, Sinus (Wall), Congenital|Nose; Deformity, Syphilitic, Late (Etiology)|Ear; Deformity, External|Ear; Deformity, Auricle, Ear, Acquired|Ear; Deformity, Auricle, Ear (Congenital)
Interventions: DEVICE: AuryzoN Family of Devices
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Role of Triptorelin 0.1 mg as a Luteal Phase Support in Assisted Reproductive Technique After Embryo Transfer : a Randomized Controlled Trial
Status: UNKNOWN
Conditions: Effect of Adding GnRHa as Luteal Phase Support in Antagonist ART Cycles
Interventions: DRUG: Effect of adding gonadotropins releasing hormone agonist to progesterone for luteal phase support in assisted reproductive technique )antagonist cycles(: a randomized controlled trial
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Clinical Performance and Wear Resistance of Highly Translucent Nano Zirconia Reinforced Glass Ionomer Filling Versus Conventional Resin Composite Restorations in Patients With Proximal Carious Teeth. (A One-year Randomized Clinical Trial).
Status: UNKNOWN
Conditions: Dental Caries
Interventions: OTHER: Zirconomer improved
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Kinesiotape Tensiomyography in Low Back Region
Status: UNKNOWN
Conditions: Bandages|Muscle Tonus|Low Back Pain
Interventions: OTHER: Kinesiotape (KT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dasatinib Combined With Chemotherapy in Relapsed t(8;21) Acute Myeloid Leukemia With KIT D816 Mutation
Status: WITHDRAWN
Conditions: Relapsed AML|T(8;21)|C-KIT Mutation
Interventions: DRUG: Dasatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Panobinostat or Placebo With Bortezomib and Dexamethasone in Patients With Relapsed Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Panobinostat|DRUG: Bortezomib|DRUG: Dexamethasone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT