pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Study to Assess the Safety and Efficacy of Etoricoxib Versus Ibuprofen in the Treatment of Dysmenorrhea (MK-0663-145 AM1)
Status: COMPLETED
Conditions: Dysmenorrhea
Interventions: DRUG: Etoricoxib|DRUG: Ibuprofen|DRUG: Placebo to etoricoxib|DRUG: Placebo to ibuprofen|DRUG: Acetaminophen 250 mg, isopropylantipyrine 150 mg and anhydrous caffeine 50 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: EFFORT Further Extension Study
Status: UNKNOWN
Conditions: Hepatitis B, Chronic
Interventions: DRUG: Telbivudine|DRUG: Adefovir dipivoxil|OTHER: off-treatment follow-up
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the NeoTree in Malawi and Zimbabwe
Status: UNKNOWN
Conditions: Prematurity|Neonatal Encephalopathy|Neonatal Sepsis|Neonatal Death|Neonatal Seizure|Neonatal Jaundice|Neonatal Hypoglycemia|Neonatal Hypothermia|Neonatal Disorder|Neonatal Respiratory Failure
Interventions: DEVICE: Neotree
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Double-Blind Study of E5555 in Japanese Subjects With Coronary Artery Disease
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DRUG: E5555 50 mg|DRUG: E5555 100 mg|DRUG: E5555 200 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Outcomes of Multiple Platforms for Assisted Robotic - Gastrectomy
Status: RECRUITING
Conditions: Gastric Cancer|Gastrointestinal Cancer|Neoplasms|Gastric Diffuse Adenocarcinoma|Gastric Neoplasm|Stomach Adenocarcinoma
Interventions: DEVICE: DaVinci® Surgical System|DEVICE: Hugo™ RAS System|DEVICE: Versius® Robotic Surgery System
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adjunctive Use of Fute (Flupentixol) in Multi-acting Receptor-targeted Antipsychotics Treated Schizophrenia Patients
Status: COMPLETED
Conditions: Schizophrenia; Psychosis|Metabolic Syndrome|Flupentixol|Antipsychotic Agents|Central Nervous System Diseases|Clinical Therapy|Olanzapine|Quetiapine
Interventions: DRUG: Flupentixol|DRUG: Multi-acting receptor-targeted antipsychotics (MARTAs)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Safety & Tolerability of BMS-906024 in Combination With Chemotherapy & to Define DLTs & MTD of BMS-906024 in Combination With One of the Following Chemotherapy Regimens; Weekly Paclitaxel, 5FU+Irinotecan or Carboplatin+Paclitaxel in Subjects With Advanced / Metastatic Solid Tumors
Status: COMPLETED
Conditions: Cancer
Interventions: DRUG: Paclitaxel|DRUG: 5-Fluorouracil (5FU)|DRUG: Carboplatin|DRUG: Leucovorin|DRUG: Irinotecan|DRUG: Paclitaxel|DRUG: BMS-906024
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Relevance of the Ethanol Dose in the Generation of Endogenous Hydroxytyrosol
Status: COMPLETED
Conditions: Contribution of Ethanol on Hydroxytyrosol Formation
Interventions: DIETARY_SUPPLEMENT: Ethanol|OTHER: Water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of the Addition of Dexmedetomidine to Bupivacaine During Supraclavicular Brachial Plexus Blockade
Status: COMPLETED
Conditions: Sequelae of Fracture of Forearm and Upper Arm
Interventions: DRUG: dexmedetomidine|DRUG: bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Efficacy of Botox in the Treatment of Social Anxiety Disorder
Status: TERMINATED
Conditions: Anxiety Disorder Social|Anxiety
Interventions: DRUG: botulinum toxin A|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Visualizing Vascular Endothelial Growth Factor (VEGF) Producing Lesions in Von Hippel-Lindau Disease
Status: COMPLETED
Conditions: Von Hippel-Lindau Disease|Hemangioblastoma|Renal Cell Carcinoma|Pheochromocytoma|Pancreatic Neuroendocrine Tumor
Interventions: OTHER: 89Zr bevacizumab PET scan
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Strength Training as Prevention and Treatment of Late Effects in Long-term Survivors of Pediatric HSCT.
Status: UNKNOWN
Conditions: Stem Cell Transplant|Late Effect|Metabolic Syndrome|Cardiovascular Diseases
Interventions: OTHER: Strength training
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: RMT in Combination With Durvalumab + Chemo in Untreated Adenocarcinoma NSCLC. A Randomized Double Blind Phase II Trial
Status: RECRUITING
Conditions: Adenocarcinoma of Lung|Lung Cancer
Interventions: DRUG: Oral Restorative Microbiota Therapy (RMT) Capsules|DRUG: Durvalumab 1500 mg IV|DRUG: Cisplatin/pemetrexed or Carboplatin/pemetrexed|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study for Participants Who Participated in Prior Clinical Studies of ASTX727 (Standard Dose), With a Food Effect Substudy at Select Study Centers
Status: ENROLLING_BY_INVITATION
Conditions: Acute Myeloid Leukemia|Chronic Myelomonocytic Leukemia|Myelodysplastic Syndromes
Interventions: DRUG: ASTX727
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Weekly Isotretinoin vs Tetracycline for Moderate Acne
Status: NOT_YET_RECRUITING
Conditions: Acne Vulgaris
Interventions: DRUG: Isotretinoin|DRUG: Tetracycline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of Bromfenac Ophthalmic Solution in Patients Undergoing Cataract Surgery
Status: COMPLETED
Conditions: Pain|Inflammation
Interventions: DRUG: Bromfenac Ophthalmic Solution|DRUG: Placebo Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Exploratory Study to Assess the Short Term Intratumoural and Peripheral Effects of BN83495 in Postmenopausal Women With Newly Diagnosed Breast Cancer
Status: TERMINATED
Conditions: Breast Cancer
Interventions: DRUG: BN83495
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: BFR Therapy After ACL Reconstruction
Status: WITHDRAWN
Conditions: ACL Injury|Quadriceps Muscle Atrophy
Interventions: DEVICE: Blood flow restriction therapy - with Delfi Personalized Tourniquet System|DEVICE: Sham blood flow restriction therapy - with Delfi Personalized Tourniquet System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MK0633 Single Dose Study in Japanese Asthmatic Children Aged 12 to Less Than 16 Years (0633-028)
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: MK0633
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Peritoneal Bridging in Laparoscopic Ventral Hernia Repair
Status: COMPLETED
Conditions: Hernia, Ventral|Laparoscopy|Seroma
Interventions: PROCEDURE: Conventional defect closure|PROCEDURE: Peritoneal bridging
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Probiotics on Cognition and Health
Status: COMPLETED
Conditions: Physiological Stress|Cognition - Other
Interventions: OTHER: Lactose Free 1% Milk|OTHER: Probiotic Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Understanding Everyday Stress
Status: COMPLETED
Conditions: Stress|Psychological Stress
Interventions: BEHAVIORAL: Self-monitoring and personalized stress management|BEHAVIORAL: Self-monitoring and general stress management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of CM310 in Patients With Chronic Rhinosinusitis With Nasal Polyposis （CROWNS-2）
Status: UNKNOWN
Conditions: Chronic Rhinosinusitis With Nasal Polyposis
Interventions: BIOLOGICAL: CM310|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Scheduling Nab-paclitaxel With Gemcitabine
Status: COMPLETED
Conditions: Pancreatic Adenocarcinoma Metastatic
Interventions: DRUG: Abraxane (nab-paclitaxel)|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: n-3 Polyunsaturated Fatty Acids (PUFAs) in the Prevention of Atrial Fibrillation
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DRUG: n-3 PUFAs|DRUG: Placebo|DRUG: RASS inhibitors and/or RAS blockers|DRUG: Amiodarone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of Tetrathiomolybdate (TM) Plus Capecitabine
Status: NOT_YET_RECRUITING
Conditions: Triple Negative Breast Cancer|Residual Disease
Interventions: DRUG: Tetrathiomolybdate|DRUG: Capecitabine|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diagnostic Value of 18F-Fluoride-PET/MRI in the Management of Suspected Facet Joint Arthropathy
Status: COMPLETED
Conditions: Arthropathy of Lumbar Facet|Pain, Back
Interventions: DEVICE: 18F-Fluoride-PET/MRI|PROCEDURE: facet injection|OTHER: pain assessment by VAS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Determine the Immunogenicity and Safety Profile of CSL Limited's Influenza Virus Vaccine Compared to a US Licensed Comparator Influenza Virus Vaccine
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: CSL Limited Influenza Virus Vaccine (Afluria®)|BIOLOGICAL: US Licensed Influenza Virus Vaccine (Fluzone®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Assessment of the Response to Etoricoxib in Patients With Ankylosing Spondylitis and Inadequate Response to ≥2 NSAIDs
Status: COMPLETED
Conditions: Ankylosing Spondylitis
Interventions: DRUG: Etoricoxib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phone-call With a Student/General Practitioner Team to Impact Morbidity of Chronic Patients During COVID-19 Containment
Status: COMPLETED
Conditions: Cardiovascular Diseases|Mental Disorder
Interventions: BEHAVIORAL: Phone-call screening and management by a medical student/general practitioner tandem
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Safety and Immunogenicity of GSK Bio's Candidate HBV-MPL Vaccines Compared to Engerix™-B, in Healthy Adolescents
Status: COMPLETED
Conditions: Hepatitis B
Interventions: BIOLOGICAL: HBV-MPL vaccine Formulation A|BIOLOGICAL: HBV-MPL vaccine Formulation B|BIOLOGICAL: Engerix™-B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy of BC LisPram
Status: UNKNOWN
Conditions: Type1 Diabetes Mellitus
Interventions: DRUG: 50-Hour Intervention - Rapid Insulin lispro|DRUG: 50-Hour Intervention - BC LisPram
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Haplo-HSCT + Rivogenlecleucel vs Haplo-HSCT + Post Transplant Cyclophosphamide in Patients With AML or MDS
Status: TERMINATED
Conditions: Acute Myeloid Leukemia|Myelodysplastic Syndromes
Interventions: BIOLOGICAL: rivogenlecleucel|DRUG: rimiducid|DRUG: Cyclophosphamide|PROCEDURE: haplo-HSCT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preoperative Radiotherapy And ASTX660 in Rectum Cancer
Status: RECRUITING
Conditions: Locally-advanced Rectal Cancer
Interventions: DRUG: mFOLFIRINOX|RADIATION: Pelvic radiotherapy LCRT|DRUG: Capecitabine|DRUG: TOLINAPANT (ASTX660)|RADIATION: Pelvic radiotherapy SCRT|DRUG: FOLFOX4|DRUG: CAPOX
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: OTX-15:003: A Phase 3 Study Evaluating the Safety and Efficacy of OTX-DP for the Treatment of Ocular Inflammation and Pain After Cataract Surgery
Status: COMPLETED
Conditions: Post-Surgical Ocular Pain|Post-Surgical Ocular Inflammation
Interventions: DRUG: Dexamethasone|OTHER: Placebo Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Test the Efficacy, Safety, and Pharmacokinetics of Rozanolixizumab in Adult Study Participants With Leucine-Rich Glioma Inactivated 1 Autoimmune Encephalitis
Status: TERMINATED
Conditions: Leucine-Rich Glioma Inactivated 1 Autoimmune Encephalitis
Interventions: DRUG: Rozanolixizumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Acetyllevocarnitine Hydrochloride Tablets in Chinese Patients With Paresthesias Caused by DPN
Status: COMPLETED
Conditions: Diabetic Peripheral Neuropathy (DPN)|Paresthesia
Interventions: DRUG: Acetyllevocarnitine Hydrochloride Tablets|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Inspiratory Muscle Training in Patients With End Stage Renal Failure
Status: UNKNOWN
Conditions: Renal Failure|Chronic Renal Insufficiency
Interventions: DEVICE: Inspiratory muscle training (URES HS730)|DEVICE: Sham inspiratory muscle training (URES HS730)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Medical Food for the Dietary Management of Advanced/Metastatic Pancreatic Cancer
Status: RECRUITING
Conditions: Metastatic Pancreatic Adenocarcinoma|Locally Advanced Unresectable Pancreatic Adenocarcinoma
Interventions: OTHER: NEAAR Medical Food
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Legionella Urine Antigen Testing (LUAT) on the Local Epidemiology and Diagnosis of Legionella Pneumonia
Status: COMPLETED
Conditions: Legionella Pneumophila Pneumonia
Interventions: DIAGNOSTIC_TEST: Immunocatch™ Legionella Urine Antigen Test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Can we Promote Bone Lengthening With Vibration Therapy?
Status: UNKNOWN
Conditions: Leg Length Discrepancy|Leg Length Difference
Interventions: DEVICE: LIV 30 Hz
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Study of BAX 930 in Children, Teenagers, and Adults Born With Thrombotic Thrombocytopenic Purpura (TTP)
Status: COMPLETED
Conditions: Thrombotic Thrombocytopenic Purpura (TTP)
Interventions: BIOLOGICAL: BAX930|BIOLOGICAL: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Cost Effectiveness Analysis for Induction of Ovulation in the Polycystic Ovary Syndrome by Letrozole Versus Clomiphene Citrate
Status: UNKNOWN
Conditions: Infertility
Interventions: DRUG: Letrozole|DRUG: Clomiphine Citrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SCREENING
Clinical trial: CMC-544 in Relapsed Refractory Acute Lymphoblastic Leukemia (ALL)
Status: COMPLETED
Conditions: Acute Lymphoblastic Leukemia
Interventions: DRUG: CMC-544 (Inotuzumab Ozogamycin)|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vitamin K2 Supplements for Muscle Recovery
Status: UNKNOWN
Conditions: Muscle Atrophy|Cachexia
Interventions: DIETARY_SUPPLEMENT: Vitamin K2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Hearing Aids With "Notched Amplification" for the Treatment of Chronic Tinnitus
Status: COMPLETED
Conditions: Tinnitus
Interventions: DEVICE: Notched filtering (verum)|DEVICE: No filtering (placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of a Scleral Lens on the Anterior Chamber Depth and Minimum Rim Width
Status: COMPLETED
Conditions: Ocular Hypertension
Interventions: DEVICE: Scleral Lens|OTHER: No lens
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL OF ENEMA ALOE VERA GEL IN ACTIVE ULCERATIVE PROCTOSIGMOIDITIS.
Status: COMPLETED
Conditions: Aloe Vera Gel, Proctosigmoiditis, Remission, Trial, Ulcerative Colitis (UC)
Interventions: DRUG: Aloe vera gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Infected Surgical Wounds With Negative Pressure Topical Therapy and Instillation (With or Without Antiseptic) Versus no Instillation
Status: UNKNOWN
Conditions: Infected Surgical Wound
Interventions: DEVICE: PTNiA|DEVICE: PTNiB|DEVICE: PTN
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: AMD3100 for Sensitizing in Allogeneic Blood or Marrow Transplant for Chemotherapy Resistant Pediatric Acute Leukemia
Status: TERMINATED
Conditions: Pediatric Acute Myeloblastic Leukemia, Relapsed|Pediatric Acute Lymphoblastic Leukemia, Relapsed
Interventions: DRUG: AMD3100
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Protocol Design for Evaluating the Immunity of Bivalve Fluids From Anodonta Cygnea in SARS and COVID-19
Status: UNKNOWN
Conditions: Coronavirus Infections|Coronavirus Sars-Associated|SARS (Severe Acute Respiratory Syndrome)|COVID-19
Interventions: BIOLOGICAL: Marine liquid and fluids|BIOLOGICAL: Impregnation|BIOLOGICAL: Incubation|BIOLOGICAL: Manipulation|BIOLOGICAL: Refrigeration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Validation of an Integrated Digital Solution (SUNrise®) Versus Polysomnography for Obstructive Sleep Apnea Diagnosis
Status: ACTIVE_NOT_RECRUITING
Conditions: Obstructive Sleep Apnea
Interventions: DEVICE: Sunrise|DEVICE: polysomnography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effects of Kinesiotaping Technique on Lung Function & Functional Capacity of Chronic Obstructive Lung Disease Patients
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: OTHER: KT|OTHER: Standardized physiotherapy protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: 70% Ethanol for Decontamination of CVL Exposed to Calcineurine Inhibitors Version 1.0, 1/9/2014
Status: COMPLETED
Conditions: Hematopoietic Stem Cell Transplant|GVHD
Interventions: OTHER: 70% Ethanol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Etiology of the Platelet-Cancer Metastatic Pathway - A Study of Inflammatory Markers, Platelet Characteristics and Metastatic Surrogates in Cancer Patients and Controls
Status: UNKNOWN
Conditions: Neoplasm
Interventions: DRUG: Everolimus|DRUG: Letrozole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Anesthetic Agents and Acute Kidney Injury After Liver Resection Surgery
Status: WITHDRAWN
Conditions: Hepatocellular Carcinoma|Hepatoma|Cholangiocarcinoma|Gallbladder Neoplasms
Interventions: DRUG: Sevoflurane|DRUG: Desflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Tanita BIA System Validation
Status: COMPLETED
Conditions: Body Composition|Circumference Measurements|Tissue Thickness Measurements
Interventions: OTHER: Body Measurements|OTHER: Body Composition and Circumference measurements|OTHER: Whole Body DXA scan|OTHER: Bioelectrical Impedance Analysis (BIA)|OTHER: BodPod|OTHER: Circumferences|OTHER: Ultrasound
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Enhancing Medication-based Analgesia in Humans
Status: COMPLETED
Conditions: Pain|Cannabis|Opioid Use, Unspecified
Interventions: DRUG: Within-subject test of blinded study medications
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: MICRO-study: The IntelliCap® System as a Gastrointestinal Fluid Sampling Tool
Status: COMPLETED
Conditions: Microbiota Composition in the Human Small Intestine
Interventions: OTHER: diet|DEVICE: IntelliCap® system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of the Antihypertensive effectIveness, Tolerability, and Adherence With Amlodipine/ Indapamide/ Perindopril Triple Single-pill Combination in Hypertensive Patients Without Concomitant Antihypertensive Therapy (TRIPTYCH)
Status: NOT_YET_RECRUITING
Conditions: Arterial Hypertension|HTN
Interventions: DRUG: Amlodipine 5 mg + indapamide 1.25 mg + perindopril 5 mg|DRUG: Amlodipine 5 mg + indapamide 2.5 mg + perindopril 10 mg|DRUG: Amlodipine 10 mg + indapamide 2.5 mg + perindopril 10 mg
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: PeRfusion Emergency VEiNlite Transillumination
Status: UNKNOWN
Conditions: Emergencies|Toxicomania|Hypotension|Obesity|Cachexia|Hypothermia
Interventions: DEVICE: transillumination dispositif
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Cerebral pAlsy Motor Promotion With Transcranial Direct Current Stimulation (CAMP-tDCS)
Status: NOT_YET_RECRUITING
Conditions: Cerebral Palsy, Hemiplegic
Interventions: DEVICE: tDCS|BEHAVIORAL: CIMT|DEVICE: sham tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Inspiratory Muscle Training on Diaphragm Thickness, Inspiratory Muscle Strength and Exercise Capacity in Individuals With Sarcopenia
Status: ACTIVE_NOT_RECRUITING
Conditions: Sarcopenia
Interventions: DEVICE: Inspiratory Muscle Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: N-Acetyl Cysteine and Aspirin as an Adjunctive Treatment for Bipolar Disorder
Status: COMPLETED
Conditions: Bipolar Disorder
Interventions: DRUG: Aspirin|DIETARY_SUPPLEMENT: N-acetyl-cysteine (NAC)|DRUG: Sugar Pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Care Given Using Levine's Conservation Model on Postpartum Quality of Life in Primiparas
Status: COMPLETED
Conditions: Breastfeeding|Quality of Life|Nursing Caries|Postpartum|Nursing Model|Levine Conservation Model
Interventions: BEHAVIORAL: breastfeeding education|BEHAVIORAL: personal hygiene education|BEHAVIORAL: nutrition education|BEHAVIORAL: fatigue education|BEHAVIORAL: sleep education|BEHAVIORAL: pilates exercises education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial Comparing Low Dose and High Dose Steroids in Patients Undergoing Colorectal Surgery
Status: COMPLETED
Conditions: Orthostatic Hypotension|Hemodynamic Instability|Fever|Hypothermia
Interventions: DRUG: Hydrocortisone High Dose|DRUG: Hydrocortisone Low Dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Needlescopic Versus Transvaginal/Transumbilical Cholecystectomy
Status: COMPLETED
Conditions: Calculus of Gallbladder With or Without Cholecystitis|Laparoscopic Cholecystectomy
Interventions: PROCEDURE: Transvaginal/transumbilical|PROCEDURE: Needlescopic with 3 trocars
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Crystal Solution and Colloid Solution on Mother and Fetus
Status: COMPLETED
Conditions: Cesarean Section|Spinal Anesthesia|Parturition
Interventions: DRUG: hydroxyethl starch|DRUG: Lactated Ringer's solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of Robotic Telesonography
Status: UNKNOWN
Conditions: Adult Abdominal Imaging|Pediatric Abdominal Imaging|Obstetric Imaging
Interventions: DEVICE: Robotic telesonography (MELODY Patient System, AdEchoTech)|DEVICE: Conventional sonography (EPIQ 5, Philips or LOGIQ E9, GE Healthcare)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy and Safety of HU007 Eye Drops in Patients With Dry Eye Syndrome
Status: COMPLETED
Conditions: Dry Eye Syndrome
Interventions: DRUG: HU007|DRUG: Restasis|DRUG: Moisview
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety Study of GSK Biologicals' Meningococcal Vaccine Given as One Dose to Healthy Subjects Above 56 Years
Status: COMPLETED
Conditions: Infections, Meningococcal
Interventions: BIOLOGICAL: Meningococcal vaccine GSK 134612|BIOLOGICAL: MencevaxACWY TM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Bevacizumab, Everolimus, and Erlotinib in Treating Patients With Advanced Solid Tumors
Status: COMPLETED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: BIOLOGICAL: bevacizumab|DRUG: erlotinib hydrochloride|DRUG: everolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Licorice Root on Metabolic Syndrome in Polycystic Ovary Syndrome Females
Status: COMPLETED
Conditions: Metabolic Syndrome|Polycystic Ovary Syndrome
Interventions: DIETARY_SUPPLEMENT: Licorice Root Powder Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Leukocyte Populations in Patients With Chronic Inflammatory
Status: NOT_YET_RECRUITING
Conditions: Systemic Autoimmune Disease|Chronic Inflammatory Rheumatism|Sjogren's Syndrome|Spondyloarthritis|Rheumatoid Arthritis|Systemic Lupus Erythematosus
Interventions: OTHER: blood sample
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluating the Safety and Effectiveness of Mozobil Mobilization in Adults With Beta-Thalassemia Major
Status: COMPLETED
Conditions: Beta-Thalassemia
Interventions: DRUG: Mozobil|DRUG: Mozobil|DRUG: Mozobil
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Open Study of the Safety, Tolerability and Immunogenicity of "Gam-COVID-Vac Lyo" Vaccine Against COVID-19
Status: COMPLETED
Conditions: Preventive Immunization COVID-19
Interventions: BIOLOGICAL: Gam-COVID-Vac Lyo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: GARDASIL 9: 3 Dose vs. 2 Dose With Delayed 3rd Dose
Status: ACTIVE_NOT_RECRUITING
Conditions: Immunization|Efficacy|Human Papilloma Virus
Interventions: BIOLOGICAL: 9-valent HPV vaccine, 2 dose efficacy|BIOLOGICAL: 9-valent HPV vaccine, 3 doses standard timing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Apixaban Versus Warfarin in the Evaluation of Progression of Atherosclerotic Calcification and Vulnerable Plaque
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DRUG: apixaban|DRUG: warfarin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: tACS for Neuropathic Pain Management After SCI
Status: NOT_YET_RECRUITING
Conditions: Neuropathic Pain Management
Interventions: DEVICE: tACS Sham|DEVICE: tACS 10Hz|DEVICE: tACS 20Hz
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of Selinexor (Seli) + Low-dose Dexamethasone (LDD) in Penta-refractory Multiple Myeloma (MM), Seli and Bortezomib + LDD in Triple-class Refractory MM, and Seli and Pomalidomide + LDD in Relapsed Refractory MM
Status: RECRUITING
Conditions: Multiple Myeloma, Refractory
Interventions: DRUG: Selinexor|DRUG: Dexamethasone|DRUG: Bortezomib|DRUG: Pomalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hymovis™ Versus Placebo in Knee Osteoarthritis
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: DEVICE: Hymovis Intra-articular Injection|PROCEDURE: Phosphate Buffered Saline Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of USG- Guided Modified Pectoral Nerve Block and Erector Spinae Plane Block on Postoperative Analgesia in Video Assisted Thoracoscopic Surgery
Status: COMPLETED
Conditions: Postoperative Analgesia|Video-assisted Thoracoscopic Surgery
Interventions: PROCEDURE: erector spina plane block|PROCEDURE: modified pectoral nerve block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Primary Mesh Closure of Abdominal Midline Wounds
Status: COMPLETED
Conditions: Incisional Hernia Occurence
Interventions: PROCEDURE: mesh supported closure|PROCEDURE: primary closure|PROCEDURE: mesh supported closure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Standard Diagnostic Procedures With or Without Fludeoxyglucose F 18 Positron Emission Tomography in Finding Cancer in Patients With a Blood Clot in a Vein
Status: COMPLETED
Conditions: Thromboembolism|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: PROCEDURE: diagnostic procedure|RADIATION: fludeoxyglucose F 18
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Long Term Safety and Efficacy of Biphasic Insulin Aspart 30 in Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: biphasic insulin aspart
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: "First-in-human" Study To Assess the Safety and Tolerability of PBF-677 in Healthy Volunteers
Status: COMPLETED
Conditions: Glaucoma
Interventions: DRUG: PBF-677|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating the Safety, Tolerability, and Pharmacokinetics of GDC-0973 in Combination With GDC-0068 When Administered in Participants With Locally Advanced or Metastatic Solid Tumors
Status: COMPLETED
Conditions: Neoplasms
Interventions: DRUG: Ipatasertib|DRUG: Cobimetinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Home-based Physical Activity Telemonitoring Program in Patients With Heart Failure and Muscle Wasting
Status: UNKNOWN
Conditions: Sarcopenia|Muscular Atrophy|Wasting Syndrome|Heart Failure
Interventions: BEHAVIORAL: home-based physical activity telemonitoring program
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Early Sedation With Dexmedetomidine vs. Placebo in Older Ventilated Critically Ill Patients
Status: NOT_YET_RECRUITING
Conditions: Respiratory Insufficiency
Interventions: DRUG: Dexmedetomidine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Benefits of Long-read High-throughput Genomic Sequencing for the Causal Diagnosis of Cerebellar Ataxias
Status: NOT_YET_RECRUITING
Conditions: Cerebellar Ataxias
Interventions: BIOLOGICAL: blood sampling for high molecular weight DNA extraction
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effects of Hemiplegic Shoulder Pain
Status: COMPLETED
Conditions: Stroke|Shoulder Pain
Interventions: OTHER: Disabilities of the Arm, Shoulder, and Hand Questionnaire|OTHER: Arm Motor Ability Test|OTHER: Nine Hole Peg Test|OTHER: Pittsburg Sleep Quality Index|OTHER: Functional Independence Measure
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Assess Safety and Tolerabiltiy Associated With a Switch From Oral Antipsychotic Medications to Long-acting Injectable Risperidone in Patients With Schizophrenia.
Status: COMPLETED
Conditions: Schizophrenia|Psychotic Disorders
Interventions: DRUG: risperidone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Outpatient and Intermittent Dosing of Elranatamab in Relapsed/Refractory Multiple Myeloma
Status: NOT_YET_RECRUITING
Conditions: Refractory Multiple Myeloma
Interventions: DRUG: Elranatamab injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Innovative Approaches to Increase F&V Intake Thru Worksites
Status: COMPLETED
Conditions: Food Habits|Eating Behavior
Interventions: OTHER: Access Intervention|BEHAVIORAL: Enhanced Intervention|BEHAVIORAL: Comparison Behavioral Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Mitomycin-C Application in Laryngotracheal Stenosis
Status: TERMINATED
Conditions: Laryngeal Stenosis|Subglottic Stenosis|Tracheal Stenosis
Interventions: DRUG: Mitomycin -C|OTHER: Saline application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fluzopalil in Combination With Anlotinib for Extensive Small-cell Lung Cancer
Status: UNKNOWN
Conditions: Extensive Stage Small Cell Lung Cancer
Interventions: DRUG: Fluzoparil|DRUG: Anlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intervention With Cerebral Embolic Protection in TEVAR: Gaseous Protection
Status: RECRUITING
Conditions: Stroke|Silent Cerebral Infarction|Neurocognitive Dysfunction|Vascular Brain Injury
Interventions: OTHER: CO2 flushing|OTHER: Saline flushing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: MK-2206 and AZD6244 in Patients With Advanced Colorectal Carcinoma
Status: COMPLETED
Conditions: Colorectal Neoplasms
Interventions: DRUG: MK-2206 + AZD6244
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of a Low-glycemic-load and Milk-free Diet on Acne Severity
Status: UNKNOWN
Conditions: Acne Vulgaris
Interventions: OTHER: Low-glycemic-load and milk-free diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Validation Of Preference Module Of Experience With Allergic Rhinitis Nasal Sprays Questionnaire (EARNS-Q)
Status: COMPLETED
Conditions: Rhinitis, Allergic, Perennial
Interventions: DRUG: Beclomethasone dipropionate|DRUG: Flunisolide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study to Validate ex Vivo Expression of Specific Biomarkers of Human Resolutive Macrophages
Status: UNKNOWN
Conditions: Inflammation
Interventions: PROCEDURE: blood sample or joint fluid or gingival exudate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Different Probiotic Strains in Hypercholesterolemic Patients
Status: COMPLETED
Conditions: Hyperlipidemias
Interventions: DIETARY_SUPPLEMENT: Only Lactobacillus rhamnosus GG strains|COMBINATION_PRODUCT: Combined Lactobacillus acidophilus and Bifidobacterium animalis subsp.lactis strains|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Safety and Immunogenicity of Fluzone® in Healthy Children
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Influenza Vaccine 2004-2005 Paediatric Formulation|BIOLOGICAL: Influenza Vaccine 2004-2005 Paediatric Formulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Non-surgical Periodontal Therapy in Patients With Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis|Periodontitis
Interventions: PROCEDURE: Non-surgical Periodontal Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Botox in the Treatment of Forward Head Posture With Associated Episodic Headache Disorder
Status: COMPLETED
Conditions: Forward Head Posture With Associated Episodic Headache Disorder
Interventions: DRUG: Botox|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Telephone Intervention for Caregivers of Persons With Traumatic Brain Injury
Status: COMPLETED
Conditions: Brain Injuries
Interventions: BEHAVIORAL: Problem-solving, education based telephone counseling|OTHER: No Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Theragun vs Dry Needling on Neck Pain, Range of Motion and Disability Among Heavy Weightlifters
Status: RECRUITING
Conditions: Dry Needling|Neck Pain|Range of Motion|Weight Lifting
Interventions: OTHER: Theragun Technique|OTHER: Dry Needling Technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: NSCLC Relapse Therapy After Surgery and Peri-operative Chemotherapy
Status: TERMINATED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: Chemotherapy with platine|DRUG: Chemotherapy without Cisplatine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cracking the Code to Better Sleep: A Pioneering Study on Remote Support for Insomnia Relief
Status: RECRUITING
Conditions: Insomnia
Interventions: BEHAVIORAL: Cognitive Behavioural Therapy for Insomnia with Motivational Interviewing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Study Comparing Long-acting Methylphenidate (ConcertaTM) vs. Placebo in the Treatment of Memory Loss Due to HIV
Status: UNKNOWN
Conditions: HIV Dementia
Interventions: DRUG: Long acting methylphenidate|DRUG: Long acting methylphenidate|DRUG: Matched placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Detecting Errors In Using Metered Dose Inhalers (MDI) Among Asthma And Chronic Obstructive Pulmonary Disease (COPD) Patients
Status: COMPLETED
Conditions: Asthma|Chronic Obstructive Pulmonary Disease
Interventions: OTHER: Education on Use of MDI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Pre-emptive Caudal Epidural Analgesia With Ropivacaine With or Without Dexamethasone in Lumbosacral Spine Surgery
Status: NOT_YET_RECRUITING
Conditions: Post Operative Pain
Interventions: DRUG: caudal epidural injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Impact of Soft Tissue Grafts on Tissue Alterations After Immediate Tooth Replacement
Status: COMPLETED
Conditions: Tooth Socket|Dental Implants
Interventions: BIOLOGICAL: Connective tissue graft|BIOLOGICAL: Collagen matrix graft|DEVICE: Immediate implant|PROCEDURE: Tooth extraction|DEVICE: Immediate restoration|BIOLOGICAL: Bone regeneration|DRUG: Post operative medication|DEVICE: Definitive prosthesis|OTHER: No soft tissue graft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Perioperative Hydrogen Inhalation on Post-operative Pain and Inflammation Cytokines
Status: UNKNOWN
Conditions: Pain, Acute
Interventions: OTHER: hydrogen inhalation, 4% concentration, given via nasal cannula
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacodynamics, Pharmacokinetics, Safety and Tolerability of SHR3824 in Type 2 Diabetes Mellitus Patients
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: SHR3824|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intravenous CTLA4-lg Treatment in Recent Onset Type 1 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus
Interventions: DRUG: CTLA-4 Ig|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: BIOPROP20: Biologically Optimised IMRT for Prostate Radiotherapy Hypofractionated Radiotherapy With Intra-prostatic Boosts to Tumour Nodules in Men With Intermediate and High Risk Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: RADIATION: Hypofractionated IMRT boost Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT