pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Efficacy and Safety Study of Haporine-S for Treatment of Moderate to Severe Dry Eye Syndromes
Status: COMPLETED
Conditions: Dry Eye Syndromes
Interventions: DRUG: Haporine-S|DRUG: Restasis (cyclosporine 0.05%)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Topical CP-690,550 For Chronic Plaque Psoriasis
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: CP-690,550|DRUG: CP-690,550|DRUG: CP-690,550|DRUG: CP-690,550|DRUG: CP-690,550|DRUG: CP-690,550|DRUG: Placebo Vehicle|DRUG: Placebo Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Curing Atopic Dermatits in Children With a Commerical Medical Device and Maintaining Healthy Skin by Using a New Cosmetic Product
Status: COMPLETED
Conditions: Dermatitis, Atopic
Interventions: DEVICE: Bepanthen Itch Relief Cream: Phoenix 2 (Bepanthen Sensiderm, BAY207543)|OTHER: New cosmetic Bepanthen product: Pumpkin (BAY207543)|OTHER: Stelatopia (cosmetic comparator)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Belimumab and Rituximab Combination Therapy for the Treatment of Diffuse Cutaneous Systemic Sclerosis
Status: RECRUITING
Conditions: Systemic Sclerosis
Interventions: DRUG: Belimumab|DRUG: Rituximab|OTHER: Placebo Subcutaneous Injection|OTHER: Placebo Infusion|DRUG: MMF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: CYCLE-AD (CYcling to Cease or Limit the Effects of Alzheimer's Disease)
Status: RECRUITING
Conditions: High Intensity Exercise|Normal Cognition|Exercise Intervention
Interventions: OTHER: Indoor Cycling (IC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of WhatsApp-Based and Face-to-face Nursing Education on Mothers' Quality of Life and Traditional Practices
Status: ACTIVE_NOT_RECRUITING
Conditions: Postpartum Period
Interventions: OTHER: WhatsApp Group|OTHER: Face-to-face Group|OTHER: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Assess the Safety, Tolerability and Pharmacokinetics of Multiple Doses of ASP8062 With a Single Dose of Morphine in Recreational Opioid Using Participants
Status: COMPLETED
Conditions: Opioid Use Disorder
Interventions: DRUG: ASP8082|DRUG: morphine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Symptom Adapted Therapy in GERD Patients
Status: COMPLETED
Conditions: Gastroesophageal Reflux Disease
Interventions: DRUG: esomeprazole|DRUG: Gelusil-Lac (Aluminum hydroxide gel,magnesium trisilicate)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neuromedulatory Effect of Transcranial Direct Current Electrical Stimulation in Carpal Tunnel Syndrome
Status: UNKNOWN
Conditions: Carpal Tunnel Syndrome
Interventions: DEVICE: transcranial direct current electrical stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparative Study of the SoftTouch Non-Invasive Finger-Mounted Device
Status: COMPLETED
Conditions: Accuracy of the SofTouch Device Measuring Blood Glucose and Other Parameters
Interventions: DEVICE: Non Invasive peripheral blood screening (Cnoga Medical Ltd.,SofTouch,OnlyTouch, CM-CL-R-007, CMC 07015922,HT 4502, HTA 4502)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Needle-Aspirated Compression Dressing Following Ostomy Reversal
Status: UNKNOWN
Conditions: Colostomy Stoma|Ileostomy - Stoma|Surgical Site Infection|Wound Complication
Interventions: PROCEDURE: Needle-Aspirated Negative Pressure Dressing|PROCEDURE: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase IIb Clinical Trial With TGF-β2 Antisense Compound AP 12009 for Recurrent or Refractory High-grade Glioma
Status: COMPLETED
Conditions: Glioblastoma|Anaplastic Astrocytoma
Interventions: DRUG: AP 12009 10 µM|DRUG: AP 12009 80 µM|DRUG: temozolomide or PCV|DEVICE: Drug delivery system for administration of AP 12009|PROCEDURE: Placement of Drug Delivery System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Accelerated rTMS for Psychomotor Slowing
Status: RECRUITING
Conditions: Schizophrenia; Psychosis|Schizophrenia and Related Disorders|Schizo Affective Disorder|Brief Psychotic Disorder
Interventions: DEVICE: cTBS (continuous Theta Burst Stimulation)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improvement of IVF Fertilization Rates, by the Cyclic Tripeptide FEE - Prospective Randomized Study
Status: TERMINATED
Conditions: Infertility|Pregnancy
Interventions: OTHER: cFFE increase the fusiogenic capacities of a gamete
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diphenhydramine in Catheter Related Bladder Discomfort
Status: ENROLLING_BY_INVITATION
Conditions: Catheter Complications
Interventions: DRUG: DiphenhydrAMINE 50 Mg/mL Injectable Solution|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Safety and Tolerability Evaluation of Two 10-Week Dose Regimens of Orally-Administered PF-04494700 in Alzheimer's Patients
Status: COMPLETED
Conditions: Alzheimer Disease
Interventions: DRUG: PF-04494700 - Low Dose Arm|DRUG: PF-04494700 - High Dose Arm|DRUG: Placebo Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Power Walking On Quality Of Life In Post CABG Patient Undergoing Phase 2 Cardiac Rehabilitation
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: OTHER: Power Walking|OTHER: Standardized Outpatient Cardiac Rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: BG9924 in Combination With Methotrexate for Participants With Active Rheumatoid Arthritis
Status: TERMINATED
Conditions: Rheumatoid Arthritis
Interventions: BIOLOGICAL: BG9924|OTHER: Placebo Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Multiple Wrist-worn Actigraphy Devices and Polysomnography
Status: WITHDRAWN
Conditions: Insomnia
Interventions: DEVICE: ActiSleep Activity Monitor|DEVICE: Jawbone Activity Monitor|DEVICE: Actiwatch 2 Activity Monitor|DEVICE: FitBit Activity Monitor|DEVICE: Actigraph by Ambulatory Monitoring Activity Monitor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Lemborexant in Delayed Sleep Phase Syndrome
Status: RECRUITING
Conditions: Delayed Sleep Phase Syndrome
Interventions: DRUG: Lemborexant|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigating the Effects of QVM149 on MRI Ventilation Defects
Status: WITHDRAWN
Conditions: Asthma
Interventions: DRUG: QVM149|DRUG: High Dose Dual Therapy (ICS/LABA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Development and Validation of a Mindfulness Intervention for Problem Gambling: An Exploratory Study
Status: COMPLETED
Conditions: Gambling
Interventions: BEHAVIORAL: Mindfulness-enhanced cognitive behavioural therapy (MCBT)|BEHAVIORAL: relaxation-enhanced cognitive behavioural therapy (RCBT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Export in Primary Percutaneous Coronary Intervention
Status: RECRUITING
Conditions: ST-segment Elevation Myocardial Infarction (STEMI)|Total Occlusion of Coronary Artery|Primary Percutaneous Coronary Intervention
Interventions: DEVICE: Export Catheter|DEVICE: Balloon catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Special Drug Use-results Survey to Evaluate Safety and Efficacy of Cosentyx in Pediatric Patients With PsV, PsA, or GPP
Status: ACTIVE_NOT_RECRUITING
Conditions: Psoriasis Vulgaris|Psoriatic Arthritis|Pustular Psoriasis
Interventions: OTHER: Cosentyx
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Storz C-MAC and D-MAC Orotracheal Intubation Systems in Morbidly Obese Patients
Status: COMPLETED
Conditions: Obesity
Interventions: DEVICE: DMAC|DEVICE: CMAC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PF-05212384 (PKI-587) for t-AML/MDS or de Novo Relapsed or Refractory Acute Myeloid Leukemia (AML)
Status: TERMINATED
Conditions: Therapy-related Acute Myeloid Leukemia and Myelodysplastic Syndrome|Acute Myeloid Leukemia, in Relapse|de Novo Acute Myeloid Leukemia at Diagnostic
Interventions: DRUG: PF-05212384
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Association Between Dapagliflozin-induced Improvement and Anemia in Heart Failure Patients (ADIDAS)
Status: RECRUITING
Conditions: Anemia|Heart Failure
Interventions: DRUG: Dapagliflozin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Clinical PRoduct DevelOpment StudyinG the QT Ultrasound® BReast ScannEr With Volunteer SubjectS
Status: UNKNOWN
Conditions: Volunteer Subjects
Interventions: OTHER: QT Ultrasound Breast Scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effectiveness and Safety of Adipose-derived Regenerative Cells for Reduction of Risk of Bladder Neck Contracture
Status: UNKNOWN
Conditions: Bladder Neck Obstruction|Bladder Outlet Obstruction|Benign Prostatic Hyperplasia|Urinary Bladder Neck Obstruction
Interventions: PROCEDURE: Liposuction|PROCEDURE: Transurethral bladder neck resection.|BIOLOGICAL: ADRC|OTHER: ADRC isolation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Epanova® Compared to Lovaza® In a Pharmacokinetic, Single-dose, Evaluation
Status: COMPLETED
Conditions: Severe Hypertriglyceridemia
Interventions: DRUG: Epanova (4 g) and Lovaza (4 g)|DRUG: Lovaza (4 g) and Epanova (4 g)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Project ASPIRE Efficacy Pilot: Achieving Superior Parental Involvement for Rehabilitative Excellence
Status: COMPLETED
Conditions: Parental Language Behaviors
Interventions: BEHAVIORAL: Linguistic Feedback Report|BEHAVIORAL: Multimedia Education Sessions|BEHAVIORAL: EI-As-Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effectiveness of Alcohol Interventions Among Tuberculosis (TB) Patients in Tomsk Oblast, Russia
Status: COMPLETED
Conditions: Tuberculosis|Alcohol Use Disorders
Interventions: BEHAVIORAL: Brief Counseling Intervention (BCI)|DRUG: Naltrexone|OTHER: BCI + Naltrexone|BEHAVIORAL: Treatment as Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Single Intravesical Doses of TTI-1612 in Women With Interstitial Cystitis/Bladder Pain Syndrome
Status: COMPLETED
Conditions: Interstitial Cystitis
Interventions: DRUG: TTI-1612
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Pharmacokinetics and Gonadotropin Suppression of Nestorone®-Testosterone (NES/T) Combination Gel in Men
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Nestorone® /testosterone gel|DRUG: Testosterone only gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Efficacy and Tolerance of the Association of ANIFROLUMAB (300mg) IV Every Four Weeks and Phototherapy Versus Phototherapy in Adults With Progressive Vitiligo
Status: RECRUITING
Conditions: Vitiligo
Interventions: DRUG: Anifrolumab Infusion Product|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An Evaluation of the Efficacy of HEXI-PREP by Clinell Wipes
Status: COMPLETED
Conditions: Antimicrobial Effect
Interventions: DRUG: HEXI-PREP By Clinell Wipes|DRUG: Chloraprep|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: A Study to Learn How Different Products of the Study Medicine Called PF-07940367 Are Taken up Into the Blood in Healthy Adults
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: PF-07940367|DRUG: PF-07940367
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase II Trial to Assess Hemodynamic Effects of Istaroxime in Pts With Worsening HF and Reduced LV Systolic Function
Status: COMPLETED
Conditions: Heart Failure
Interventions: DRUG: Istaroxime|DRUG: Istaroxime|DRUG: Istaroxime|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Distraction on Procedure-Related Emotional Appearance, Pain, Fear, and Anxiety During Phlebotomy in Children
Status: COMPLETED
Conditions: Pain, Acute|Fear|Anxiety State
Interventions: DEVICE: virtual reality|BEHAVIORAL: stress ball
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of Inhibitory Control Processes Induced by Rectal Distension on Impulse Control Measured by Stroop Task Performance and Intertemporal Discounting.
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: OTHER: induction of urge by rectal distension
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Multidimensional Assessment of Quality of Life, Social and Professional Life and Care Utilization in Patients With Diffuse Large Cell B-cell Lymphoma Treated With CAR-T Cells
Status: NOT_YET_RECRUITING
Conditions: Diffuse Large B-cell Lymphoma (DLBCL)|CAR-T Cells Treatment
Interventions: OTHER: self-administered questionnaires
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: CPAP Effect on Lipid Profile and Hyperuricemia in Patients With Dyslipidemia and Moderate-severe Obstructive Sleep Apnea
Status: RECRUITING
Conditions: Sleep Apnea|Dyslipidemias|Hyperuricemia
Interventions: DEVICE: Continuous positive airway pressure|OTHER: Hygienic-dietary recommendations and daily physical activity promotion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Addressing Neuromuscular Deficits for Improved Outcomes in Ankle Rehabilitation
Status: RECRUITING
Conditions: Ankle Sprains
Interventions: OTHER: SMART Intervention|OTHER: Standard of Care Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study To Examine Safety, Tolerability And Pharmacokinetics Of Intravenous Doses And Oral Dose Of GSK233705
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: GSK233705
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Allogenic Bone Marrow Transplantation (BMT) Compare With Cytoreduction and Chemotherapy in Acute Lymphoblastic Leukemia (ALL) Patients
Status: COMPLETED
Conditions: Acute Lymphoblastic Leukemia
Interventions: PROCEDURE: Bone Marrow Transplantation|PROCEDURE: Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of SAR442720 in Combination With Other Agents in Advanced Malignancies
Status: TERMINATED
Conditions: Metastatic Neoplasm
Interventions: DRUG: SAR442720|DRUG: Pembrolizumab|DRUG: Adagrasib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Fractionated 90Y-hPAM4 Plus Gemcitabine in Pancreatic Cancer Patients Receiving at Least 2 Prior Therapies.
Status: WITHDRAWN
Conditions: Metastatic Pancreatic Adenocarcinoma|Pancreatic Cancer|Metastatic Pancreatic Cancer
Interventions: DRUG: 90Y-hPAM4|DRUG: 90Y-hPAM4|DRUG: 90Y-hPAM4 + gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Low Dose Lenalidomide and Dexamethasone in Relapsed/Refractory Myeloma in Patients at High Risk for Myelosuppression
Status: UNKNOWN
Conditions: Multiple Myeloma
Interventions: DRUG: Lenalidomide|DRUG: dexamethasone|DRUG: aspirin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PRS-343 in HER2-Positive Solid Tumors
Status: COMPLETED
Conditions: HER2-positive Breast Cancer|HER2-positive Gastric Cancer|HER2-positive Bladder Cancer|HER2-positive Solid Tumor
Interventions: DRUG: PRS-343
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Emervel® Deep Lidocaine vs. Juvederm® Ultra Plus in Treatment of Moderate to Severe Facial Wrinkles and Folds
Status: COMPLETED
Conditions: Skin Wrinkling
Interventions: DEVICE: Emervel Deep Lidocaine|DEVICE: Juvederm Ultra Plus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Open Label, Multicentre Trial to Assess Safety and Efficacy of ITF2357 in Active Systemic Juvenile Idiopathic Arthritis
Status: COMPLETED
Conditions: Active Systemic|Onset Juvenile Idiopathic Arthritis
Interventions: DRUG: ITF2357
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Effectiveness and Stimulation Coverage of Closed-loop Spinal Cord Stimulation (CL-SCS) Therapy in Patients With Cervical Lead Placement
Status: ENROLLING_BY_INVITATION
Conditions: Chronic Pain Syndrome|Multi Focal Pain|Failed Neck Surgery Syndrome|Polyneuropathies
Interventions: DEVICE: cervical lead placement
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: ILLUMENATE Pivotal Post-Approval Study (PAS)
Status: COMPLETED
Conditions: Peripheral Artery Disease
Interventions: DEVICE: Stellarex 0.035" OTW Drug-coated Angioplasty Balloon|DEVICE: EverCross™ 0.035 PTA Balloon Catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Low-frequency Electroacupuncture (EA) on Polycystic Ovary Syndrome
Status: COMPLETED
Conditions: Polycystic Ovary Syndrome
Interventions: OTHER: acupuncture protocol 1|OTHER: Acupuncture protocol 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vorinostat in Treating Patients With Progressive Metastatic Prostate Cancer
Status: COMPLETED
Conditions: Recurrent Prostate Cancer|Stage IV Prostate Cancer
Interventions: DRUG: vorinostat|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: B Cell Tailored Ocrelizumab Versus Standard Ocrelizumab in Relapsing Remitting Multiple Sclerosis
Status: RECRUITING
Conditions: Multiple Sclerosis, Relapsing-Remitting
Interventions: DRUG: Ocrelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Understand Risk and Resilience Opportunity for Newborns After Delivery
Status: ACTIVE_NOT_RECRUITING
Conditions: A. Longitudinal Cohort n=400|B. Lower Risk (n=45) and Higher Risk (n=105) Randomized 2:1 to PERCCS Intervention
Interventions: BEHAVIORAL: PERCCS: Personalized Education Regarding Clinical and Community Supports
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Study to Assess the Effects of an Oral Dietary Supplement on Overall Facial Appearance Among Healthy Adult Women With Existing Skin Damage From Sun Exposure
Status: COMPLETED
Conditions: Photodamaged Skin
Interventions: DIETARY_SUPPLEMENT: Imedeen|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Phase Ib/II Study of Buparlisib Plus Carboplatin or Lomustine in Patients With Recurrent Glioblastoma Multiforme
Status: COMPLETED
Conditions: Recurrent Glioblastoma Multiforme
Interventions: DRUG: buparlisib|DRUG: carboplatin|DRUG: lomustine|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Study of Regorafenib as Maintenance Therapy
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Soft Tissue Sarcoma
Interventions: DRUG: Regorafenib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Mesenchymal Stem Cell Therapy (MSCs) and Conditioned Medium Therapy for Osteoartrithis
Status: RECRUITING
Conditions: Osteoarthritis, Knee
Interventions: BIOLOGICAL: Arthroscopy with Mesenchymal Stem Cells + Secretome + Secretome|BIOLOGICAL: Arthroscopy with Secretome + Mesenchymal Stem Cells + Secretome|BIOLOGICAL: Non Arthroscopy with Mesenchymal Stem Cells + Secretome + Secretome|BIOLOGICAL: Non Arthroscopy with Secretome + Mesenchymal Stem Cells + Secretome
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Luspatercept for Anemia in Lower Risk MDS or Non-proliferative MDS/MPN Neoplasms
Status: RECRUITING
Conditions: Myelodysplastic Syndromes|Myeloproliferative Neoplasm|Anemia
Interventions: DRUG: Luspatercept
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Envafolimab Combined With Chemoradiotherapy and Recombinant Human Endostatin for LA-NPC.
Status: RECRUITING
Conditions: Nasopharyngeal Carcinoma
Interventions: DRUG: Envafolimab and recombinant human endostatin combined with chemoradiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of CHK-336 in Healthy Volunteers
Status: TERMINATED
Conditions: Healthy Volunteers
Interventions: DRUG: CHK336|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: SYMPLICITY HTN-3 Renal Denervation in Patients With Uncontrolled Hypertension
Status: COMPLETED
Conditions: Uncontrolled Hypertension
Interventions: DEVICE: Renal denervation (Symplicity Catheter System)|DIAGNOSTIC_TEST: Renal angiogram
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Whether Food Has an Effect on the Uptake of Solifenacin and Tamsulosin When Administered in a Combination Tablet
Status: COMPLETED
Conditions: EC905|Pharmacokinetics|Healthy Subjects
Interventions: DRUG: EC905
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Biological Therapy in Treating Patients Undergoing Radiation Therapy, Chemotherapy, and Peripheral Stem Cell Transplantation for Hematologic Cancer
Status: COMPLETED
Conditions: Leukemia|Lymphoma|Oral Complications
Interventions: BIOLOGICAL: filgrastim|BIOLOGICAL: palifermin|DRUG: cyclophosphamide|DRUG: etoposide|DRUG: ifosfamide|PROCEDURE: peripheral blood stem cell transplantation|PROCEDURE: quality-of-life assessment|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Intraprostatic Injection of Botulinum Toxin A Versus Ethanol for Treatment of Patients With Benign Prostatic Hyperplasia
Status: COMPLETED
Conditions: Male|Ultrasonography|Botulinum Toxins, Type A|Injection; Complications, Infection|Prostatic Hyperplasia
Interventions: PROCEDURE: Botulinum toxin A|PROCEDURE: Ethanol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Behavioral Activation, Nutrition, and Activity Intervention
Status: NOT_YET_RECRUITING
Conditions: HIV
Interventions: BEHAVIORAL: Social Connection|BEHAVIORAL: Nutritional Coaching|BEHAVIORAL: Physical Activity Coaching
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Changes in Insulin Resistance in Healthy Volunteers on STRIBILD® Medication
Status: COMPLETED
Conditions: Insulin Resistance
Interventions: DRUG: Tenofovir disaproxil fumarate/emtricitabine/elvitegravir/cobicistat|DRUG: Tenofovir disaproxil fumarate/emtricitabine + Lopinavir/ritonavir|DRUG: Tenofovir disaproxil fumarate/emtricitabine + ritonavir-boosted darunavir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: N-acetylcysteine to Reduce Oxidative Stress and Improve Endothelial Function in HIV-infected Older Adults
Status: COMPLETED
Conditions: HIV|Endothelial Dysfunction|Oxidative Stress
Interventions: DIETARY_SUPPLEMENT: PharmaNAC (N-acetylcysteine)|DIETARY_SUPPLEMENT: Matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Peritoneum Vaginoplasty; Implementation According to IDEAL Framework
Status: RECRUITING
Conditions: Rokitansky Kuster Hauser Syndrome|Vaginal Neoplasms|Gender Incongruence|Vaginal Obstruction|Penoscrotal Hypoplasia
Interventions: PROCEDURE: Laparoscopic pedicled single flap peritoneum vaginoplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Prospective Study of Misoprostol Administration in Asymptomatic Patients With Pregnancies of Unknown Location
Status: UNKNOWN
Conditions: Pregnancies of Unknown Location (PUL)
Interventions: DRUG: CYTOTEC|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Quality of Life of Adults With Diffuse Large B-cell Lymphoma Treated With Tisagenlecleucel
Status: TERMINATED
Conditions: Lymphoma, Large B-Cell, Diffuse
Interventions: BEHAVIORAL: Digital Health Coaching
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study to Assess the Efficacy and Safety of Tizaspray® Versus Sirdalud®, in Patients With Acute Low Back Pain
Status: COMPLETED
Conditions: Low Back Pain
Interventions: DEVICE: Tizaspray® administered intranasally|DRUG: Sirdalud® 2 mg tablets administered
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stanford Letter or Traditional Advance Directive in Advance Care Planning in Patients Undergoing Bone Marrow Transplant
Status: COMPLETED
Conditions: Advance Directives|Bone Marrow Transplant
Interventions: OTHER: Stanford Letter|OTHER: Interview|OTHER: Questionnaire Administration|OTHER: CA Advance Health Care Directive Form
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Congestive Heart Failure Surgical Treatmment With Autologous Stem Cell Therapy
Status: UNKNOWN
Conditions: Congestive Heart Failure
Interventions: PROCEDURE: intramiocardiac autograft of autologous stem cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Temozolomide & RT Followed by Dose Dense vs Temozolomide & Retinoic Acid in Pts w/Glioblastoma
Status: COMPLETED
Conditions: Glioblastoma|Gliomas
Interventions: DRUG: Temozolomide|DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Body Weights Via Visual Estimation, Anthropometric Calculation, and Actual Measured in Critically Ill Patients
Status: RECRUITING
Conditions: Critically Ill|Body Weight
Interventions: DEVICE: patient transfer scale
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Impact of tDCS on Cannabis Craving in Schizophrenia
Status: NOT_YET_RECRUITING
Conditions: Schizophrenia|Cannabis Use Disorder
Interventions: DEVICE: tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acceptance and Commitment Therapy for Depressed Individuals Living With Spinal Cord Injury Sustained Within 5 Years
Status: RECRUITING
Conditions: Depression|Spinal Cord Injuries
Interventions: BEHAVIORAL: Acceptance and commitment therapy (ACT)|BEHAVIORAL: Wait-list control group with psychoeducation materials provided
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial to Evaluate the Potential Benefit of Adjuvant Chemotherapy for Small Bowel Adenocarcinoma
Status: RECRUITING
Conditions: Small Bowel Adenocarcinoma
Interventions: DRUG: Fluoropyrimidine|DRUG: Oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dry Needling Versus Percutaneous Electrolysis in Lumbar Multifidus Muscles in Patients With Chronic Low Back Pain.
Status: NOT_YET_RECRUITING
Conditions: Chronic Low-back Pain
Interventions: OTHER: Dry needling|OTHER: Percutaneous electrolysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Effect of Increased Gastric pH on the Oral Bioavailability of the Orexin-2 Receptor Antagonist JNJ-42847922 in Healthy Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: JNJ-42847922|DRUG: Rabeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Exercise and Yogurt on Bone Mineral Density and Immunological Factors in Human Milk: The MEEMA Study
Status: TERMINATED
Conditions: Lactational Amenorrhea|Body Weight Changes|Bone Loss
Interventions: OTHER: Exercise and dietary
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Nurse-Guided BBTi for Improving Insomnia : in Patients at the Recovery Following Traumatic Brain Injury
Status: RECRUITING
Conditions: Insomnia|Traumatic Brain Injury
Interventions: BEHAVIORAL: Nurse-guided BBTi group|BEHAVIORAL: Mobile-delivered BBTi group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Study of an Investigational Drug, Patisiran (ALN-TTR02), for the Treatment of Transthyretin (TTR)-Mediated Amyloidosis in Participants Who Have Already Been Treated With ALN-TTR02 (Patisiran)
Status: COMPLETED
Conditions: Amyloidosis
Interventions: DRUG: Patisiran
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Selinexor in People With Wilms Tumors and Other Solid Tumors
Status: RECRUITING
Conditions: Wilms Tumor|Rhabdoid Tumor|Malignant Peripheral Nerve Sheath Tumors|MPNST|Nephroblastoma|XPO1 Gene Mutation|Solid Tumor
Interventions: DRUG: Selinexor
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Laparoscopic Versus Open Gastrectomy With Splenic Hilum Lymph Nodes Dissection
Status: UNKNOWN
Conditions: Gastric Cancer
Interventions: PROCEDURE: Laparoscopic total gastrectomy|PROCEDURE: Open total gastrectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Motivational Enhancement Therapy to Improve Adherence to Aromatase Inhibitors
Status: UNKNOWN
Conditions: Breast Cancer|Medication Adherence
Interventions: BEHAVIORAL: Motivational enhancement therapy|BEHAVIORAL: Attention Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: GLP-1 Receptor Agonist for Reduction of Myocardial Injury After Non-cardiac Surgery
Status: NOT_YET_RECRUITING
Conditions: Myocardial Injury
Interventions: DRUG: Semaglutide 0.25mg subcutaneous injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Pedometer-based Intervention With and Without Email Counselling in General Practice
Status: COMPLETED
Conditions: Physical Activity|Primary Care|General Practice
Interventions: BEHAVIORAL: pedometer-plus-email|BEHAVIORAL: pedometer-only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety, Pharmacokinetics, and Pharmacodynamics of BIRT 2584 XX Administered as Multiple Doses and Safety and Pharmacokinetics of BIRT 2584 XX Administered With and Without Food as Single Dose to Healthy Male Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BIRT 2584 XX - multiple escalating dose|DRUG: Placebo|DRUG: BIRT 2584 XX - single dose|OTHER: high caloric meal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Bioavailability Study of SPARC001 (Study 2) in Healthy Adult Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: SPARC001 type I|DRUG: SPARC001 type II|DRUG: Reference001 type I|DRUG: Reference001 type II
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II SBRT & Chemo for Unresectable Cholangiocarcinoma Followed by Liver Transplantation
Status: TERMINATED
Conditions: Cholangiocarcinoma|Hepatobiliary Neoplasm|Liver Cancer|Bile Duct Cancer|Cancer of Gallbladder
Interventions: PROCEDURE: Stereotactic Body Radiotherapy|DRUG: Gemcitabine|DRUG: Cisplatin|DRUG: Carboplatin|DRUG: Capecitabine|DRUG: 5FU|PROCEDURE: Liver transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Vismodegib (GDC-0449, Hedgehog Pathway Inhibitor) As Maintenance Therapy in Patients With Ovarian Cancer in a Second or Third Complete Remission
Status: COMPLETED
Conditions: Ovarian Cancer
Interventions: DRUG: Vismodegib 150 mg|DRUG: Placebo to vismodegib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Tocilizumab in Combination With DMARD Therapy in Patients With Active Rheumatoid Arthritis.
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: tocilizumab [RoActemra/Actemra]|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Solitaire™ With the Intention For Thrombectomy as PRIMary Endovascular Treatment (SWIFT PRIME) Trial
Status: COMPLETED
Conditions: Acute Ischemic Stroke
Interventions: DRUG: Intravenous (IV) recombinant human tissue plasminogen activator (rtPA)|DEVICE: Solitaire revascularization device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Osteopathic Manual Treatment Parkinson's Disease and Truncal Dystonia
Status: COMPLETED
Conditions: Parkinson Disease|Dystonia|Autonomic Dysreflexia
Interventions: OTHER: osteopathic manual therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Epinephrine and Cortisol in Depression
Status: WITHDRAWN
Conditions: Depression
Interventions: DRUG: Hydrocortisone Acetate (CORT)|DRUG: Epinephrine Sulfate (EPI)|DRUG: Placebo (PLB)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Premedication Properties of Oral Melatonin in Pediatrics Undergoing Therapeutic Cardiac Catheterization
Status: NOT_YET_RECRUITING
Conditions: Anesthesia
Interventions: DRUG: melatonin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: GC 2nd Line Durvalumab(MEDI4736)/Tremelimumab Plus Paclitaxel Study
Status: COMPLETED
Conditions: Metastatic Gastric Cancer
Interventions: DRUG: durvalumab, tremelimumab, paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Muscle Activity, Bite Force and Salivary Cortisol in Children With Bruxism
Status: UNKNOWN
Conditions: Sleep Bruxism
Interventions: DEVICE: Laser|DEVICE: Occlusal splint|DEVICE: Placebo laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Motion Analysis of EMP Knee Versus Posterior Stabilized Knee Arthroplasty for Osteoarthritis
Status: COMPLETED
Conditions: Arthropathy of Knee Joint
Interventions: PROCEDURE: Total Knee Arthroplasty|PROCEDURE: Motion analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Clinical Trial to Assess The Efficacy and Safety of the Combination of Tisagenlecleucel And Ibrutinib in Mantle Cell Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Mantle Cell Lymphoma Recurrent
Interventions: COMBINATION_PRODUCT: ibrutinib and Tisagenlecleucel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dietary Supplements for COVID-19
Status: TERMINATED
Conditions: Covid19
Interventions: DRUG: Vitamin D3 50,000 IU|DIETARY_SUPPLEMENT: Vitamin C/Zinc|DIETARY_SUPPLEMENT: Vitamin K2/D|OTHER: Microcrystalline Cellulose Capsule|OTHER: Medium Chain Triglyceride Oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fluoroscopic and RSA Evaluation of the Triathlon Total Knee Prosthetic Design
Status: TERMINATED
Conditions: Complications; Arthroplasty, Mechanical|Aseptic Loosening
Interventions: DEVICE: Triathlon PS total knee system with mobile-bearing|DEVICE: Triathlon PS total knee system with fixed-bearing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Multicenter, Prospective, Non-interventional, Observational Study to Confirm the Long-term Efficacy and Safety of Rosuampin Tab. in Patients With Hypertension and Hypercholesterolemia
Status: ACTIVE_NOT_RECRUITING
Conditions: Hypertension|Hypercholesterolemia
Interventions: DRUG: Rosuampin 5/5mg, 10/5mg, 20/5mg, 10/10mg
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: PIMA - Individualized Adherence Improvement Plan
Status: UNKNOWN
Conditions: Sleep Apnea, Obstructive
Interventions: BEHAVIORAL: Motivational Interview (MI) & Adherence Follow-Up|DEVICE: Adherence Follow-Up
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: An Investigational Study of Infliximab With Prednisone or Methylprednisolone Versus Prednisone Combination Treatment in Immune Related or Severe Diarrhea in Patients Treated With Yervoy and/or Opdivo
Status: WITHDRAWN
Conditions: Renal Cell Carcinoma|Melanoma|Lung Cancer
Interventions: DRUG: Infliximab + Prednisone|DRUG: Methylprednisolone + Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Local Anesthetic and Clonidine on the Cutaneous Silent Period During Spinal Anesthesia
Status: ACTIVE_NOT_RECRUITING
Conditions: Inguinal Hernia|Spinal Anesthesia
Interventions: DRUG: levobupivacaine|DRUG: clonidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bilateral Transforaminal Epidural Steroid Injections for Degenerative Lumbar Spinal Stenosis
Status: TERMINATED
Conditions: Spinal Stenosis, Lumbar Region, With Neurogenic Claudication
Interventions: DRUG: bilateral transforaminal epidural steroid injections
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Palisade Lateral Branch Technique Using Multi-tined Needles for Sacro-iliac Joint Radiofrequency Ablation
Status: RECRUITING
Conditions: Sacroiliac; Backache|Chronic Pain
Interventions: PROCEDURE: Palisade sacroiliac joint radiofrequency ablation using 3-tined needles
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Efficacy and Safety of Bimagrumab in Patients After Hip Fracture Surgery
Status: COMPLETED
Conditions: Muscle Wasting (Atrophy) After Hip Fracture Surgery
Interventions: DRUG: bimagrumab|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Perineural Injection Therapy in Patients With Carpal Tunnel Syndrome
Status: COMPLETED
Conditions: Carpal Tunnel Syndrome
Interventions: PROCEDURE: Ultrasound-guided perineural injection with 5% dextrose|PROCEDURE: Ultrasound-guided perineural injection with normal saline|DRUG: Normal Saline|DRUG: 5% Dextrose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of the Composition From Fish on Promoting Hair Growth
Status: COMPLETED
Conditions: Hair Loss/Baldness|Androgenic Alopecia|Male Pattern Baldness|Female Pattern Alopecia
Interventions: OTHER: SF DNA extraction composition|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER