pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Development of a Software Tool, Using Artificial Intelligence, That Integrates Clinical, Biological, Genetic and Imaging Data to Predict Diagnosis and Outcome of Depressed Patients in Order to Enhance Prognosis and Limiting Healthcare Costs.
Status: RECRUITING
Conditions: Bipolar Disorder|Unipolar Depression
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Liposomal Doxorubicin and Carboplatin in Treating Patients With Gynecologic Cancer
Status: COMPLETED
Conditions: Cervical Cancer|Endometrial Cancer|Fallopian Tube Cancer|Ovarian Cancer|Sarcoma
Interventions: DRUG: carboplatin|DRUG: pegylated liposomal doxorubicin hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study of SD-101 (a Novel C Type Toll-like Receptor 9 (TLR9) Agonist) for the Treatment of Chronic Hepatitis C Virus (HCV) Infection
Status: COMPLETED
Conditions: Chronic Hepatitis C
Interventions: DRUG: SD-101|DRUG: ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Supporting Prescribing in Irish Primary Care: General Practice Pharmacist Study
Status: COMPLETED
Conditions: Polypharmacy|Multimorbidity
Interventions: OTHER: Main Study|OTHER: PROM Study
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: New Therapeutical Perspectives in Cases of Phonological Disorders
Status: COMPLETED
Conditions: Speech Sound Disorders
Interventions: BEHAVIORAL: Traditional Phonological Therapy|BEHAVIORAL: Software Phonological Therapy- SIFALA|BEHAVIORAL: Placebo Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: AccuVein AV400 Device Versus Ultrasound-guided Cannulation of the Great Saphenous Vein at the Ankle in Infants
Status: UNKNOWN
Conditions: Intravenous Cannulation
Interventions: DEVICE: AccuVein AV400 Device Versus Ultrasound-guided Cannulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Pharmacodynamics, Safety and Tolerability of Oral BL-7040 in Patients With Moderately Active Ulcerative Colitis
Status: COMPLETED
Conditions: Ulcerative Colitis
Interventions: DRUG: BL-7040
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Metabolic and Cognitive Consequences of Noise-induced Sleep Disturbance
Status: COMPLETED
Conditions: Noise Exposure|Sleep Disturbance|Sleep Hygiene|Metabolic Disturbance|Cognitive Change
Interventions: RADIATION: Pink noise exposure|RADIATION: Traffic noise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety and Immunogenicity of Direct Venous Inoculation of a Radiation-attenuated PfSPZ Vaccine in Equatoguinean Adults
Status: COMPLETED
Conditions: Malaria|Plasmodium Falciparum
Interventions: BIOLOGICAL: PfSPZ Vaccine|OTHER: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: TheraSphere for the Treatment of Liver Metastases
Status: COMPLETED
Conditions: Colorectal Cancer|Carcinoma, Neuroendocrine|Neoplasm Metastasis
Interventions: DEVICE: Yttrium 90 glass microspheres
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Post-Revascularization Optimization and PHysiological Evaluation of intermediaTe Lesions
Status: RECRUITING
Conditions: Ischemic Heart Disease|Angina, Stable|Non ST Elevation Myocardial Infarction|ST Elevation Myocardial Infarction|Unstable Angina|Coronary Disease
Interventions: DIAGNOSTIC_TEST: Invasive functional evaluation with either Pd/Pa, FFR, iFR or contrast FFR
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Nab-paclitaxel in Sensitive and Refractory Relapsed SCLC
Status: UNKNOWN
Conditions: Small Cell Lung Cancer
Interventions: DRUG: Nabpaclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Comparative Effectiveness of Initial OAB Treatment Options Among Older Women at High Risk of Falls
Status: RECRUITING
Conditions: Urinary Bladder, Overactive|Urinary Incontinence|Accidental Falls
Interventions: BEHAVIORAL: Pelvic Floor Muscle Training|DRUG: Mirabegron|DRUG: Trospium Chloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multiparametric Cardiac MRI in Patients Under CAR T-cell Therapy
Status: RECRUITING
Conditions: DLBCL|Multiple Myeloma|Cytokine Release Syndrome|Myocarditis|CAR T-cell Therapy|ALL|PCBCL|Follicular Lymphoma|MCL
Interventions: DIAGNOSTIC_TEST: Cardiac MRI
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Dynamic Stability Exercises in Patients With Hypermobile Ehlers-Danlos Syndrome and Hypermobility Spectrum Disorder
Status: COMPLETED
Conditions: Hypermobility Syndrome|Hypermobile Ehlers-Danlos Syndrome
Interventions: BEHAVIORAL: Dynamic stability exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Prepopik® in Children for Overall Colon Cleansing in Preparation for Colonoscopy
Status: COMPLETED
Conditions: Need for Bowel Preparation
Interventions: DRUG: Prepopik® ½ Sachet x 2 (9-12 years)|DRUG: Prepopik® 1 Sachet x 2 (9-12 years)|DRUG: Oral polyethylene glycol (PEG) based preparation (9-12 years)|DRUG: Prepopik® 1 Sachet x 2 (13-16 years)|DRUG: Oral polyethylene glycol (PEG) based preparation (13-16 years)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Omega-3 Fatty Acids Efficacy in First-episode of Schizophrenia
Status: UNKNOWN
Conditions: Schizophrenia
Interventions: DIETARY_SUPPLEMENT: essential fatty acids|DIETARY_SUPPLEMENT: olive oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: High-Flow Nasal Cannula and Desaturation Episodes in the Morbidly Obese Patients
Status: COMPLETED
Conditions: Desaturation of Blood|Obesity|Colonoscopy|Sleep Apnea|High Flow Nasal Cannula
Interventions: DEVICE: The Comfort Flo system|DEVICE: The Salter nasal cannula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of the Effect of MN-504 Cobiotic Formulation on the Efficacy and Tolerability of Metformin
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: OTHER: NM504
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Neural and Psychological Mechanisms of Pain Perception
Status: RECRUITING
Conditions: Pain|Normal Physiology|Healthy Volunteers
Interventions: BEHAVIORAL: Instructions|BEHAVIORAL: Attention|BEHAVIORAL: Thermal Pain|BEHAVIORAL: Placebo instructions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: To Study the Effect of Adjunctive Oral Methylprednisolone Therapy in Pediatric Urinary Tract Infection
Status: UNKNOWN
Conditions: Urinary Tract Infection
Interventions: DRUG: Methylprednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Meningococcal C Vaccine Programmes in Canadian Children
Status: COMPLETED
Conditions: Meningococcal Sero-type C Infection
Interventions: BIOLOGICAL: NeisVac C vaccine (12mth)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: The Effect of Mindfulness-Based Self-Compassion Education Given to Parents of Children With Autism Spectrum Disorder
Status: COMPLETED
Conditions: Autism Spectrum Disorder
Interventions: BEHAVIORAL: Session 1|BEHAVIORAL: Session 2|BEHAVIORAL: Session 3|BEHAVIORAL: Session 4|BEHAVIORAL: Session 5|BEHAVIORAL: Session 6|BEHAVIORAL: Session 7|BEHAVIORAL: Session 8|BEHAVIORAL: Session 9|BEHAVIORAL: Session 10
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Borderline Resectable Pancreatic Cancer Neoadjuvant Chemoradiotherapy Clinicaltrial-1
Status: RECRUITING
Conditions: Pancreatic Cancer
Interventions: DRUG: Neoadjuvant gemcitabine plus nab-paclitaxel|DRUG: Neoadjuvant gemcitabine plus nab-paclitaxel with SBRT|DRUG: Neoadjuvant S-1 plus nab-paclitaxel with SBRT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: UC Cohort - The Influence of Diet on Gut Microbiotas
Status: COMPLETED
Conditions: Ulcerative Colitis
Interventions: DIETARY_SUPPLEMENT: High Protein and Low Fiber Diet|DIETARY_SUPPLEMENT: Low Protein and High Fiber Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Demonstration of a Decongestant Effect of "Coldamaris Akut" Compared to Saline Nasal Spray.
Status: COMPLETED
Conditions: Allergic Rhinitis|Allergic Rhinoconjunctivitis
Interventions: DEVICE: nasal spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Liraglutide on Pancreatic Hormones and Its Size
Status: COMPLETED
Conditions: Obesity
Interventions: DRUG: Liraglutide (Saxenda) 6Mg/Ml Inj Pen 3Ml
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effectiveness of Tailored Rehabilitation Education on Health Literacy and Health Status of Postoperative Patients With Breast Cancer: a Randomized Controlled Trial
Status: COMPLETED
Conditions: Health Behavior
Interventions: OTHER: tailored education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: To Explore Cognitive Neural Mechanism of Autoimmune Encephalitis by Using Neuropsychological Tests and Multi-modal MRI
Status: COMPLETED
Conditions: Cognitive Impairment|Autoimmune Encephalitis
Interventions: DRUG: rituximab|DRUG: cyclophosphamide|DRUG: Steroids|DRUG: Intravenous immunoglobulin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Circadian Influence on Prolonged Exposure Therapy for PTSD
Status: RECRUITING
Conditions: PTSD
Interventions: BEHAVIORAL: Prolonged Exposure Therapy for Posttraumatic Stress Disorder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Adjuvant PROSTVAC-V/F in Subjects at High Risk for Relapse After Radical Prostatectomy
Status: COMPLETED
Conditions: Prostatic Neoplasms
Interventions: BIOLOGICAL: PROSTVAC-V/F
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Management With Fear of Cancer in Women Undergoing Colposcopy: Randomized Controlled Study
Status: RECRUITING
Conditions: Cancer Fear|Cervical Cancer
Interventions: BEHAVIORAL: Awareness-Based Coping with Fear of Cancer Programme
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of the Effects of Increasing Doses of a Drug for the Treatment of Nail Fungus
Status: COMPLETED
Conditions: Onychomycosis
Interventions: DRUG: Albaconozole|DRUG: Placebo|DRUG: Albaconozole|DRUG: Placebo|DRUG: Albaconozole|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Clinical Trial About the Safety of Surgical Treatment in Severe Primary Pontine Hemorrhage
Status: RECRUITING
Conditions: Cerebrovascular Disorders|Pontine Hemorrhage|Primary|Surgery
Interventions: PROCEDURE: hematoma evacuation by craniotomy|PROCEDURE: hematoma evacuation by stereotactic puncture|PROCEDURE: hematoma evacuation by neuroendoscopy|OTHER: life support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effectiveness of Home-Use Desensitizing Agents on Dentin Hypersensitivity
Status: COMPLETED
Conditions: Dentin Sensitivity
Interventions: OTHER: Control group|OTHER: Arginine|OTHER: Novamin|OTHER: Propolis|OTHER: Casein Phosphopeptide Amorphous Calcium Phosphate|OTHER: Potassium Nitrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Can Vitamin D3 Supplementation Affect Treatment Outcomes in Patients With Depression
Status: UNKNOWN
Conditions: Depression
Interventions: DIETARY_SUPPLEMENT: Vitamin D3|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bone Physiology & Mechanics in Osteomyoplasty Amputation Rehabilitation
Status: TERMINATED
Conditions: Amputation|Fracture|Inflammation|Osteoporosis
Interventions: BEHAVIORAL: Amputation rehabilitation exercise program|PROCEDURE: Osteomyoplasty vs. routine long posterior flap
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Effects of Ordinary and Differential Learning Based Physiotherapy on Subjects With Ischemic Stroke Torso Control, Balance and Gait in the Second Phase of Rehabilitation
Status: COMPLETED
Conditions: Ischemic Stroke
Interventions: OTHER: Intervention group|OTHER: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: MNK-6105 for Patients With Cirrhosis and High Ammonia Levels Affecting Brain Function
Status: WITHDRAWN
Conditions: Hepatic Encephalopathy
Interventions: DRUG: MNK-6105|DRUG: Placebo|DRUG: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Healthy Volunteer Pilot Study Using 3 Types of Modified Release Formulations of Firategrast to Investigate How Quickly Absorption From the Digestive System Takes Place.
Status: COMPLETED
Conditions: Multiple Sclerosis, Relapsing-Remitting
Interventions: DRUG: A|DRUG: B|DRUG: C|DRUG: D
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Blueberry Enhances Activity and Cognition Through Increased Vascular Efficiency
Status: COMPLETED
Conditions: Sedentary Lifestyle|Blood Pressure|Arterial Stiffness|Overweight and Obesity
Interventions: DIETARY_SUPPLEMENT: Blueberry Plus Exercise (BB-EX)|DIETARY_SUPPLEMENT: Blueberry Placebo Plus Exercise (P-EX)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of GRT-R910 COVID-19 Boost Vaccine in Healthy Volunteers
Status: COMPLETED
Conditions: COVID-19
Interventions: BIOLOGICAL: GRT-R910 10 mcg Dose (after AZ)|BIOLOGICAL: GRT-R910 30 mcg Dose (after AZ)|BIOLOGICAL: GRT-R910 10 mcg Dose (After Adenovirus based vaccine)|BIOLOGICAL: GRT-R910 10 mcg Dose (after mRNA based vaccine)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of Single And Double Bundle Anterior Cruciate Ligament (ACL) Graft Cross-sectional Dimensions
Status: UNKNOWN
Conditions: Rupture of Anterior Cruciate Ligament
Interventions: PROCEDURE: single bundle ACL reconstruction|PROCEDURE: double bundle ACL reconstruction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combinating Fingolimod With Alteplase Bridging With Thrombectomy in Acute Ischemic Stroke
Status: RECRUITING
Conditions: Stroke|Inflammation
Interventions: DRUG: Fingolimod|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transforming Robot-mediated Telerehabilitation: Citizen Science for Rehabilitation
Status: RECRUITING
Conditions: Hemiparesis|Stroke
Interventions: BEHAVIORAL: Output-Focus Condition|BEHAVIORAL: Input-Focus Condition
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Dose-escalating Therapeutic Study of Allogeneic Bone Marrow Derived Mesenchymal Stem Cells for the Treatment of Fistulas in Patients With Refractory Perianal Crohn's Disease
Status: COMPLETED
Conditions: Crohn's Disease|Fistula
Interventions: PROCEDURE: Localization, curettage of the fistulous tract and closure of the internal opening without MSC injection.|PROCEDURE: Localization, curettage of the fistulous tract and closure of the internal opening with local MSC injection.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Management of Antiplatelet Drug Resistance in Patients With Drug Eluting Coronary Stents
Status: WITHDRAWN
Conditions: Coronary Artery Disease
Interventions: DRUG: Plavix (Clopidogrel)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Manual Therapy With TECAR in Woman With Chronic Neck Pain
Status: ACTIVE_NOT_RECRUITING
Conditions: Neck Pain
Interventions: OTHER: Manual Therapy with TECAR|OTHER: Manual Therapy without TECAR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD0780 in Healthy Subjects
Status: COMPLETED
Conditions: Dyslipidemia
Interventions: DRUG: AZD0780|DRUG: AZD0780|DRUG: AZD0780|DRUG: Placebo|DRUG: Placebo|DRUG: Placebo|DRUG: Rosuvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety of Desloratadine in Children With Allergy Sensitivity and Chronic Hives, Who Are Poor Metabolizers of Desloratadine (Study P02994)
Status: COMPLETED
Conditions: Chronic Idiopathic Urticaria|Atopy
Interventions: DRUG: desloratadine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Gemcitabine in Treating Children With Relapsed or Refractory Acute Lymphoblastic Leukemia or Acute Myelogenous Leukemia
Status: COMPLETED
Conditions: Leukemia
Interventions: DRUG: gemcitabine hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Role of Dietary Tryptophan on Aryl Hydrocarbon Receptor Activation
Status: COMPLETED
Conditions: Diet Modification
Interventions: DIETARY_SUPPLEMENT: L-tryptophan|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Stylet Shape in Simulated Endotracheal Intubation by Medical Students
Status: RECRUITING
Conditions: Endotracheal Intubation|Medical Education
Interventions: PROCEDURE: Endotracheal intubation using an endotracheal tube with a 30 degree straight to cuff shape|PROCEDURE: Endotracheal intubation using an endotracheal tube with an arcuate cuff shape
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: OTHER
Clinical trial: ONL1204 Ophthalmic Solution in Patients With Geographic Atrophy Associated With Age-related Macular Degeneration
Status: COMPLETED
Conditions: Geographic Atrophy
Interventions: DRUG: ONL1204 Ophthalmic solution|PROCEDURE: sham injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Efficacy of Platelets Treated With Pathogen Reduction Process
Status: COMPLETED
Conditions: Aplasia With Expected Thrombocytopenia
Interventions: BIOLOGICAL: Autologous plasma|BIOLOGICAL: Additive solution|BIOLOGICAL: Pathogen reduction process
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Exercise Therapy to Reduce Heart Failure Symptoms; Sorting Mechanisms of Benefit
Status: COMPLETED
Conditions: Heart Failure
Interventions: BEHAVIORAL: Aerobic Exercise Intervention|BEHAVIORAL: Combined Aerobic and Strength Exercise Intervention|BEHAVIORAL: Inspiratory Muscle Training Exercise Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Self-sampling for Non-participants in an Organised Cervical Cancer Screening Programme
Status: COMPLETED
Conditions: Cervical Cancer
Interventions: BEHAVIORAL: HPV self-sampling kit mailed directly|BEHAVIORAL: HPV self-sampling kit on demand|BEHAVIORAL: Second reminder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Nutrition, Inflammation and Insulin Resistance in End Stage Renal Disease-Aim 2
Status: COMPLETED
Conditions: ESRD
Interventions: DRUG: anakinra|DRUG: actos|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intensive Lipid-lowering for Plaque and Major Adverse Cardiovascular Events in Low to Intermediate 10-year ASCVD Risk Population
Status: RECRUITING
Conditions: Coronary Artery Disease Progression
Interventions: DRUG: Intensive lipid-lowering control|DRUG: Moderate-intensity lipid-lowering control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison Between Serratus Anterior Plane Block and Erector Spinae Plane Block for Mastectomy
Status: COMPLETED
Conditions: Breast Cancer Postoperative Pain
Interventions: PROCEDURE: Plane block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Prospective Randomized Endovascular Therapy in Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: OTHER: Venous Angioplasty|OTHER: Sham Angioplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Coversin in Paroxysmal Nocturnal Haemoglobinuria (PNH)
Status: COMPLETED
Conditions: Paroxysmal Nocturnal Haemoglobinuria (PNH)
Interventions: DRUG: Coversin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Pazopanib and Ixabepilone in Patients With Solid Tumors
Status: TERMINATED
Conditions: Breast Cancer|Lung Cancer|Colon Cancer|Pancreatic Cancer|Head and Neck Cancer|Kidney Cancer|Sarcoma|Hepatocellular Cancer
Interventions: DRUG: Pazopanib|DRUG: Ixabepilone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Sorafenib on ccRCC Uptake of Radiolabeled Bevacizumab or cG250
Status: COMPLETED
Conditions: Clear Cell Renal Cell Carcinoma
Interventions: DRUG: Sorafenib|DRUG: 111Indium-bevacizumab|DRUG: 111Indium-cG250
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effectiveness, Immunogenicity and Safety of Meningococcal ABCWY Vaccine Administered to Healthy Adolescents
Status: COMPLETED
Conditions: Meningococcal Disease
Interventions: BIOLOGICAL: MenABCWY|OTHER: Placebo|BIOLOGICAL: MenACWY
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Practical Nomogram Based on Systemic Inflammatory Markers for Predicting Portal Vein Thrombosis in Patients With Liver Cirrhosis
Status: COMPLETED
Conditions: Systemic Inflammatory Markers|Portal Vein Thrombosis
Interventions: DIAGNOSTIC_TEST: clinical laboratory tests, and imaging characteristics
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Evaluate Pazopanib as an Adjuvant Treatment for Localized Renal Cell Carcinoma (RCC)
Status: COMPLETED
Conditions: Renal Cell Carcinoma (RCC)|Cancer
Interventions: DRUG: pazopanib|DRUG: placebo|DRUG: pazopanib|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Erector Spinae Plane Block or Serratus Anterior Plane (SAP) Block Following Video Assisted Thoracic Surgery
Status: COMPLETED
Conditions: Lung Diseases
Interventions: OTHER: ESP block (Group ESP)|OTHER: SAP block (Group SAP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficiency Study of Siwu Tang to Treat Brain Hypoperfusion Syndrome
Status: UNKNOWN
Conditions: Brain Hypoperfusion Syndrome|Ischemia Brain
Interventions: DRUG: Siwu Tang
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic of Tadalafil Co-administered With Tipranavir/Ritonavir to Healthy Male Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Tadalafil|DRUG: Tipranavir|DRUG: Ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Combination Product (Sumatriptan Succinate and Naproxen Sodium) in Migraine Subjects Who Report Poor Response or Intolerance to Short Acting Triptans (Study 1 of 2)
Status: COMPLETED
Conditions: Migraine Disorders
Interventions: DRUG: Combination Product (sumatriptan succinate / naproxen sodium)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Skills-based RCT for Physical Activity Using Peer Mentors
Status: COMPLETED
Conditions: Health Behavior|Obesity|Motor Activity
Interventions: BEHAVIORAL: Mentoring to be Active with Accelerometers|BEHAVIORAL: Planning to be Active with Accelerometers
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Phase 3 Study Evaluating Safety and Effectiveness of Immune Globulin Intravenous (IGIV 10%) for the Treatment of Mild-to-Moderate Alzheimer´s Disease
Status: COMPLETED
Conditions: Alzheimer´s Disease
Interventions: BIOLOGICAL: Immune Globulin Intravenous (Human), 10% (IGIV, 10%) 400 mg/kg|BIOLOGICAL: Immune Globulin Intravenous (Human), 10% (IGIV, 10%) 200 mg/kg|BIOLOGICAL: Placebo solution: Human Albumin 0.25% - 4 mL/kg|BIOLOGICAL: Placebo solution: Human Albumin 0.25% - 2 mL/kg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: PICk-UP: PersonalIsed CommUnity-based Physical Activities for Patients With Chronic Obstructive Pulmonary Disease
Status: COMPLETED
Conditions: COPD
Interventions: OTHER: Community-based physical activity programme|OTHER: Pulmonary Rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Early Versus Delayed Carotid Endarterectomy (CEA) for Small to Medium-sized Ischemic Stroke Caused by High-grade Carotid Stenosis
Status: WITHDRAWN
Conditions: Stroke|Carotid Stenosis
Interventions: PROCEDURE: carotid endarterectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of 100% Medical Grade Manuka Honey on Tympanic Membrane Reconstruction Healing.
Status: COMPLETED
Conditions: Otitis Media, Suppurative|Tympanic Membrane Perforation
Interventions: DRUG: Manukamed - Manukapli 100% sterile honey wound dressing - Premium medical grade 16+ Leptospermum Scoparium New Zealand honey
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy and Tolerability of Tonabersat in the Prophylaxis of Migraine Headache
Status: COMPLETED
Conditions: Migraine Without Aura|Migraine With Aura
Interventions: DRUG: Tonabersat|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Total Joint Arthroplasty (TJA) Weight Loss Study
Status: RECRUITING
Conditions: Osteoarthritis, Hip|Osteoarthritis, Knee|Obesity, Morbid
Interventions: PROCEDURE: Bariatric surgery|BEHAVIORAL: Medical weight loss|OTHER: Patient research surveys|PROCEDURE: Total joint arthroplasty (TJA)|OTHER: Usual standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Pharmacokinetics of Three Dosages of Niagen in Healthy Subjects
Status: COMPLETED
Conditions: Pharmacokinetics
Interventions: DIETARY_SUPPLEMENT: Niagen 100mg|DIETARY_SUPPLEMENT: Niagen 300mg|DIETARY_SUPPLEMENT: Niagen 1000mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Safety and Expulsion of Delayed Versus Immediate Postpartum Intrauterine Device Placement
Status: TERMINATED
Conditions: Contraception
Interventions: DEVICE: Mirena (levonorgestrel-releasing intrauterine system)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Shockwave C2+ 2Hz Coronary IVL Catheter in Calcified Coronary Arteries (Disrupt CAD DUO)
Status: RECRUITING
Conditions: Coronary Artery Disease|Myocardial Infarction
Interventions: DEVICE: IVL with Shockwave C2+ 2Hz Coronary IVL Catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Diode Laser in Maturogenesis of Immature Teeth With Necrotic Pulps
Status: COMPLETED
Conditions: Effects of the Elements
Interventions: DEVICE: Diode laser disinfection|DEVICE: Diode Laser bio-stimulation.|DRUG: Triple antibiotic paste disinfection|PROCEDURE: revascularization using the standard method "Blood Clot"
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Silmitasertib (CX-4945) in Combination With Chemotherapy for Relapsed Refractory Solid Tumors
Status: NOT_YET_RECRUITING
Conditions: Neuroblastoma Recurrent|Ewing's Sarcoma Recurrent|Osteosarcoma Recurrent|Rhabdomyosarcoma Recurrent|Liposarcoma Recurrent
Interventions: DRUG: Silmitasertib|DRUG: Irinotecan|DRUG: Temozolomide|DRUG: Vincristine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Learn More About the Effect of a New Drug Called BAY2327949 on the Blood Flow Through Kidneys in Adult Participants With Moderate Chronic Kidney Disease
Status: TERMINATED
Conditions: Moderate Chronic Kidney Disease
Interventions: DRUG: BAY2327949|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of Tadalafil Use With Finasteride in Men With Enlarged Prostates and Urinary Symptoms
Status: COMPLETED
Conditions: Benign Prostatic Hyperplasia|Enlarged Prostate
Interventions: DRUG: Tadalafil|DRUG: Placebo|DRUG: Finasteride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Post Isometric Relaxation Versus Myofascial Release Therapy in the Management of Non Specific Neck Pain
Status: COMPLETED
Conditions: Neck Pain
Interventions: OTHER: 1.Post Isometric Relaxation|OTHER: 1.Myofascial Release therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Uses of Titanium Nail in Pediatric Fractures
Status: RECRUITING
Conditions: Trauma Injury of Upper Extremity Forearm Multiple|Fracture of Distal End of Radius
Interventions: PROCEDURE: Distal radius fracture fixation in pediatrics.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of PPI-668, BI 207127 and Faldaprevir, With and Without Ribavirin, in the Treatment of Chronic Hepatitis C
Status: COMPLETED
Conditions: Chronic Hepatitis C
Interventions: DRUG: PPI-668|DRUG: BI 207127 Dose 1|DRUG: BI 207127 Dose 2|DRUG: Faldaprevir|DRUG: Ribavirin|DRUG: BI 207127 Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety of Vaccine Against Tetanus and Diphtheria.
Status: ACTIVE_NOT_RECRUITING
Conditions: Diphtheria|Tetanus
Interventions: BIOLOGICAL: Clodivac|BIOLOGICAL: Td-Impfstoff Merieux
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Spatial and Dynamic Characterization of Brain Activity for Language and Posture (Verticality) During Normal Aging. Magnetoencephalography (MEG) Study (MEG-AGING)
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: BEHAVIORAL: Cognitive tasks
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effectiveness of a Cardiac Rehabilitation Program in Elderly Patients With Heart Failure.
Status: RECRUITING
Conditions: Heart Failure With Preserved Ejection Fraction|Sarcopenia|Frail Elderly Syndrome|Comorbidities and Coexisting Conditions
Interventions: PROCEDURE: Cardiac Rehabilitation Program (CR)|BEHAVIORAL: Control Group (CG)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mindfulness Relaxation Compared With Relaxing Music and Standard Symptom Management Education in Treating Patients Who Are Undergoing Chemotherapy For Newly Diagnosed Solid Tumors
Status: COMPLETED
Conditions: Chemotherapy-induced Nausea and Vomiting|Unspecified Adult Solid Tumor, Protocol Specific|Breast Cancer|Gastrointestinal Cancer|Disease (or Disorder); Gynecological|Prostate Cancer
Interventions: BEHAVIORAL: MR Therapy|BEHAVIORAL: Relaxing Music (RM) Therapy|BEHAVIORAL: Standard Symptom Management|BEHAVIORAL: Questionnaires
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Clinical Study of CEA-targeted CAR-T Therapy for CEA-positive Advanced/Metastatic Malignant Solid Tumors
Status: RECRUITING
Conditions: Gastric Cancer|Colon Cancer|Pancreas Cancer|Esophagus Cancer|Cholangiocarcinoma|Lung Cancer|Breast Cancer
Interventions: BIOLOGICAL: CEA CAR-T cells|BIOLOGICAL: CEA CAR-T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of Palivizumab in Japanese Newborns, Infants and Young Children at the Age of 24 Months or Less With Immunocompromised Medical Conditions
Status: COMPLETED
Conditions: Respiratory Syncytial Virus Infection
Interventions: DRUG: Palivizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: SP-304 Dose Ranging Study in Patients With Chronic Idiopathic Constipation
Status: COMPLETED
Conditions: Chronic Idiopathic Constipation
Interventions: DRUG: SP-304 0.3 mg|DRUG: SP-304 1.0 mg|DRUG: SP-304 3.0 mg|DRUG: SP-304 9.0 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: High-Dose Weekly Carfilzomib Plus Cyclophosphamide and Dexamethasone in the Treatment of Relapsed Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Carfilzomib|DRUG: Cyclophosphamide|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Nicotine Pouches Among Daily Smokers
Status: NOT_YET_RECRUITING
Conditions: Tobacco Dependence
Interventions: OTHER: 0 mg nicotine pouch|OTHER: 3 mg nicotine pouch|OTHER: 6 mg nicotine pouch|OTHER: Smooth nicotine pouch|OTHER: Wintergreen nicotine pouch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Vaccination by Leukemic Apoptotic Corpse Autologous Pulsed Dendritic Cells for Acute Myelogenous Leukemia (AML) Patients in First or Second Complete Remission (CR)(CD laM)
Status: UNKNOWN
Conditions: Acute Myelogenous Leukemia
Interventions: OTHER: cell therapy product|PROCEDURE: injection of the cell therapy product
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oxulumis® Suprachoroidal Microcatherization of Triesence® in Diabetic Macular Edema
Status: COMPLETED
Conditions: Diabetic Macular Edema
Interventions: DRUG: Triamcinolone Acetonide|DEVICE: Semi-automated Suprachoroidal Microcatheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Caphosol® Versus State-of-the-art Mouthcare in Patients With Allogeneic Stem Cell Transplantation: a Randomized Controlled Study About the Efficacy of the Mouth Rinse Caphosol®
Status: COMPLETED
Conditions: Allogeneic Stem Cell Transplantation
Interventions: DEVICE: Caphosol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Virus and Bronchial Epithelium in Children and the Elderly
Status: RECRUITING
Conditions: SARS-CoV-2
Interventions: BIOLOGICAL: SARS-CoV-2|BIOLOGICAL: Adenovirus (AdV)|BIOLOGICAL: Rhinovirus|BIOLOGICAL: No Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Preoxygenation With Nasal Cannula and Noninvasive Positive Pressure Ventilation
Status: COMPLETED
Conditions: Hypoxia
Interventions: DEVICE: Ventilation with nasal cannula|DEVICE: Ventilation without nasal cannula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Impacts of PIO/MET Following Short-term Intensive Insulin Treatment in Newly Diagnosed Type 2 Diabetes
Status: UNKNOWN
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Pioglitazone + Metformin|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Safety and Tolerability Study of JNJ-42160443 in Patients With Moderate to Severe, Chronic Knee Pain From Osteoarthritis
Status: TERMINATED
Conditions: Osteoarthritis|Osteoarthritis, Knee|Pain|Arthralgia|Joint Pain
Interventions: DRUG: Oxycodone CR (standard pain medication)|DRUG: JNJ-42160443|DRUG: JNJ-42160443|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intra-Individual Reproducibility of the Non-Invasive Assessment of the Portal Circulation
Status: COMPLETED
Conditions: Hepatitis C, Chronic|Non-Alcoholic Fatty Liver Disease
Interventions: DEVICE: Cholate-24-13C (IND 65121) & Cholate-2,2,4,4-d4 (IND 65123)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Does a Multi-ingredient Pre-workout Supplement Enhance Cycling Time Trial Performance?
Status: UNKNOWN
Conditions: Healthy Volunteers
Interventions: DIETARY_SUPPLEMENT: Ladder Supplement|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Subcutaneous-Sublingual Immunotherapy With Depigmented and Polymerized Dermatophagoides Pteronyssinus Allergen Extract
Status: TERMINATED
Conditions: Allergic Asthma
Interventions: BIOLOGICAL: DEPIGOID Dermatophagoides pteronyssinus|BIOLOGICAL: Polymerized TOL of Dermatophagoides pteronyssinus|BIOLOGICAL: Placebo Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety of Accelerated Rule-out Protocols in Patients Admitted With Chest Pain to a Crowded Chest Pain Unit (CPU)
Status: COMPLETED
Conditions: Acute Coronary Syndrome|NSTEMI - Non-ST Segment Elevation MI
Interventions: DIAGNOSTIC_TEST: NSTEMI Rule-Out according to hs-TnT
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Randomized Controlled Trial of Acupuncture in Treating Migraine
Status: UNKNOWN
Conditions: Migraine Without Aura
Interventions: PROCEDURE: Acupuncture combined with placebo|PROCEDURE: Sham acupuncture combined with flunarizine hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Carboplatin, Paclitaxel, and Bevacizumab in Treating Patients With Stage IV Melanoma That Cannot Be Removed By Surgery
Status: COMPLETED
Conditions: Recurrent Melanoma|Stage IV Melanoma
Interventions: DRUG: carboplatin|DRUG: paclitaxel|BIOLOGICAL: bevacizumab|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Action of Photodynamic Therapy on Wound Quality and Tissue Repair in the Diabetic Foot
Status: NOT_YET_RECRUITING
Conditions: Diabetic Foot Ulcer
Interventions: PROCEDURE: antimicrobial photodynamic therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Dose Ranging Study of the Aeris Polymeric Lung Volume Reduction (PLVR) System in Patients With Advanced Upper Lobe Predominant Emphysema
Status: COMPLETED
Conditions: Advanced Emphysema
Interventions: DEVICE: Polymeric Lung Volume Reduction System (PLVR)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Flufirvitide-3 Nasal Spray in Healthy Subjects
Status: COMPLETED
Conditions: Influenza
Interventions: DRUG: Flufirvitide-3 0.05 mg single dose|DRUG: Flufirvitide-3, 0.1 mg single dose|DRUG: Flufirvitide-3, 0.2 mg single dose|DRUG: Flufirvitide-3, 0.4 mg single dose|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: BAY 0 9867 Cipro Pediatric Use Study (QUIP)
Status: COMPLETED
Conditions: Infectious Diseases
Interventions: DRUG: Ciprofloxacin|DRUG: Non-quinolone antibiotic
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT