pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Modification of the "Edmonton Protocol" to Allow for Successful Islet Transplantation From a Single Pancreas and Extension of the "Edmonton Protocol" to Kidney Transplant Recipients
Status: UNKNOWN
Conditions: Diabetes Mellitus
Interventions: PROCEDURE: human cadaveric islet cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Detection of Coronary Stenosis With Intravenous Microbubbles
Status: WITHDRAWN
Conditions: Coronary Stenosis|Carotid Stenosis|Myocardial Reperfusion
Interventions: DRUG: Optison|DRUG: Definity|DRUG: PESDA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Addition of Carboplatin to Neoadjuvant Therapy for Triple-negative and HER2-positive Early Breast Cancer
Status: COMPLETED
Conditions: Tubular Breast Cancer Stage II|Mucinous Breast Cancer Stage II|Breast Cancer Female NOS|Invasive Ductal Breast Cancer|Tubular Breast Cancer Stage III|HER-2 Positive Breast Cancer|Inflammatory Breast Cancer Stage IV|Inflammatory Breast Cancer
Interventions: DRUG: Carboplatin|DRUG: background treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Electrophysiology, Safety, Tolerability, Pharmacokinetics and Pharmacodynamics Response Using Magnetic Resonance Imaging of SAGE-718 Using a Ketamine Challenge in Healthy Subjects
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: SAGE-718|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Impact of Donor Diabetes on DMEK Success and Endothelial Cell Loss
Status: ACTIVE_NOT_RECRUITING
Conditions: Corneal Endothelial Decompensation|Fuchs' Endothelial Dystrophy
Interventions: PROCEDURE: Descemet membrane endothelial keratoplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Cognitive Behavioral Therapy With Panic Control Treatment for Adolescents With Panic Disorder
Status: COMPLETED
Conditions: Panic Disorder
Interventions: BEHAVIORAL: Cognitive behavioral therapy (CBT) with panic control treatment (PCT) for adolescents|BEHAVIORAL: Waitlist control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ankle Proprioceptive Training In Patients With Diabetic Peripheral Neuropathy
Status: COMPLETED
Conditions: Diabetic Peripheral Neuropathy
Interventions: OTHER: Ankle proprioceptive training (APT)|OTHER: Balance training (BT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: BE Study of the Combinations of Gemigliptin 50mg and Metformin HCl Extended Release 500mg in Comparison to Each Component Administered Alone
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: gemigliptin and metformin HCl extended release|DRUG: gemigliptin/metformin HCl extended release
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Quetiapine SR and Divalproex Sodium ER in the Treatment of Anxiety in Bipolar Disorder With Panic Disorder and/or GAD
Status: COMPLETED
Conditions: Bipolar Disorder|Panic Disorder|Generalized Anxiety Disorder
Interventions: DRUG: quetiapine SR|DRUG: divalproex sodium ER|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: 5-year Follow up Study on the Comparative Performance of Two-piece Zirconia and Titanium Implants
Status: RECRUITING
Conditions: Dental Implants|Single Tooth Lost|Dental Implant Failed
Interventions: DEVICE: Ceramic Dental Implant|DEVICE: Titanium Dental Implant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Does Tranexamic Acid Improve Visualization During Arthroscopic Rotator Cuff Repair
Status: UNKNOWN
Conditions: Rotator Cuff Tears|Rotator Cuff Injuries|Subacromial Impingement|Subacromial Impingement Syndrome
Interventions: DRUG: Tranexamic Acid 100 MG/ML
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Life-long Monitoring of COPD in Veneto Region
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: PROCEDURE: self-monitoring for patients with severe COPD|PROCEDURE: nurse-monitoring for patients with severe COPD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy Study of Recombinant Interleukin-21 in the Treatment of Ovarian Cancer
Status: COMPLETED
Conditions: Cancer|Ovarian Cancer
Interventions: DRUG: recombinant interleukin-21|DRUG: caelyx (pegylated liposomal doxorubicin)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics of Valacyclovir Oral Solution in Children
Status: TERMINATED
Conditions: Herpes Simplex Virus Infection|Varicella Zoster Virus Infection
Interventions: DRUG: Valacyclovir
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Sequential High-Dose Chemotherapy and Stem Cell Transplantation in Treating Patients With Chemotherapy-Sensitive Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: BIOLOGICAL: filgrastim|DRUG: cyclophosphamide|DRUG: megestrol acetate|DRUG: melphalan|DRUG: tamoxifen citrate|DRUG: thiotepa|PROCEDURE: conventional surgery|PROCEDURE: peripheral blood stem cell transplantation|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Adolescent Community Reinforcement Approach in Combination With Buprenorphine/Naloxone for Severe Opioid Use
Status: WITHDRAWN
Conditions: Opioid-Related Disorders|Behavior, Addictive
Interventions: BEHAVIORAL: Adolescent Community Reinforcement Approach (A-CRA)|OTHER: Combination of buprenorphine/naloxone 4/1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Safety and Pharmacokinetic Profile of CPL-01 in the Management of Acute Postoperative Pain
Status: COMPLETED
Conditions: Abdominoplasty
Interventions: DRUG: CPL-01|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cerebrovascular and Cognitive Improvement by Resveratrol (resVida) and Fruitflow-II (CCIRF-II)
Status: UNKNOWN
Conditions: Memory Impairment
Interventions: DRUG: Fruitflow-II|DRUG: resVida
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Investigational Study of Experimental Medication BMS-986231 Given in Participants With Different Levels of Liver Function
Status: COMPLETED
Conditions: Liver Dysfunction|Liver Insufficiency|Hepatic Failure|Myocardial Failure|Cardiac Failure|Congestive Heart Failure|Heart Decompensation
Interventions: DRUG: BMS-986231
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gemcitabine Hydrochloride and Smac Mimetic TL32711 in Treating Patients With Advanced Solid Tumors
Status: TERMINATED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: Smac mimetic TL32711|DRUG: gemcitabine hydrochloride|OTHER: laboratory biomarker analysis|OTHER: pharmacological study|PROCEDURE: biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CLUE: CLinical Utility Study of EsoGuard
Status: RECRUITING
Conditions: Barrett Esophagus|Barretts Esophagus With Dysplasia|Esophagus Adenocarcinoma
Interventions: DEVICE: EsoGuard
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Kava for the Treatment of Generalised Anxiety Disorder: A Double-Blind Randomised Placebo-Controlled Trial
Status: COMPLETED
Conditions: Generalized Anxiety Disorder
Interventions: DIETARY_SUPPLEMENT: Kava (240mg of kavalactones per day)|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Green Laser Photocoagulation Study in Proliferative Diabetic Retinopathy
Status: COMPLETED
Conditions: Diabetic Retinopathy
Interventions: DEVICE: Green Laser (Aurolas, Aurolab)|DEVICE: Green Laser (Iridex)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Plaque REgression With Cholesterol Absorption Inhibitor or Synthesis Inhibitor Evaluated by IntraVascular UltraSound
Status: COMPLETED
Conditions: Hypercholesterolemia|Coronary Artery Disease
Interventions: DRUG: Combination therapy with Lipitor [Atorvastatin] and Zetia [Ezetimibe]|DRUG: Lipitor (Atorvastatin) monotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Single Center, Randomized, Double-blind, Crossover Pilot Trial Comparing the Onset of Action of Parcopa™ With Sinemet® in Subjects With Stable Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DRUG: Parcopa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose:
Clinical trial: HepciFer Study: Hepcidin Overexpression After Hepatectomy : Does Iron Supplementation Make Sense ?
Status: COMPLETED
Conditions: Anemia|Postoperative Blood Loss
Interventions: DRUG: IV iron|DRUG: IV placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Pilot Study of Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF) in Generalized Myasthenia Gravis
Status: UNKNOWN
Conditions: Myasthenia Gravis
Interventions: DRUG: Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Feasibility and Effect of an Individualized Physical Activity Intervention for Gastric Cancer Patient Undergoing Minimally Invasive Gastrectomy: a Pilot Study
Status: COMPLETED
Conditions: Gastric Cancer Patient
Interventions: BEHAVIORAL: physical activity intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of Implementation of a National Point-of-Care Ultrasound Training Program
Status: COMPLETED
Conditions: Other Acute Illnesses Presenting to the Hospital|Heart Failure|Pneumonia|Deep Venous Thrombosis|Cellulitis|Abdominal Aortic Aneurysm|Acute Cholecystitis|Peritoneal Free Fluid|Hydronephrosis|Pleural Effusion|Urinary Retention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Metabolic Effects of Atazanavir/Ritonavir Versus Darunavir/Ritonavir in Combination With Tenofovir/Emtricitabine in naïve HIV-1 Infected Patients
Status: COMPLETED
Conditions: HIV-1
Interventions: DRUG: Darunavir / Ritonavir + Tenofovir / Emtricitabine|DRUG: Atazanavir / Ritonavir + Tenofovir / Emtricitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Citalopram Hydrobromide Tablets 40 mg of Dr.Reddy's Laboratories Limited Under Fed Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Citalopram Hydrobromide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dry Needling for Provoked Vestibulodynia
Status: RECRUITING
Conditions: Provoked Vestibulodynia
Interventions: OTHER: Real Dry needling|OTHER: Non penetrating dry needling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: HIV-1 Infection Study of Once a Day Versus Twice a Day Protease Inhibitor in Antiretroviral Treatment Naive Adults
Status: COMPLETED
Conditions: Infection, Human Immunodeficiency Virus I|HIV-1 Infection
Interventions: DRUG: fosamprenavir/ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ipsilateral Hepatic Vein Embolization After Portal Vein Embolization
Status: COMPLETED
Conditions: Procedure-Related Complication|Degree of Liver Regeneration
Interventions: PROCEDURE: Right hepatic vein embolization
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Gum Arabic Ingestion on Hormonal and Metabolic Changes in Patients With Polycystic Ovary Syndrome
Status: UNKNOWN
Conditions: Polycystic Ovary Syndrome
Interventions: DIETARY_SUPPLEMENT: Acacia Senegal extract|DIETARY_SUPPLEMENT: Pectin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of the optImuM Dose of calcineUrin Inhibitor and Mycophenolate Sodium in Kidney Recipients
Status: COMPLETED
Conditions: Kidney Transplantation
Interventions: DRUG: routine dose tacrolimus and less myfortic|DRUG: reduced dose tacrolimus and conventional myfortic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 1, Two-part, Randomized Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of a Liquid Formulation of Tricaprilin and Matching Placebo in Healthy Subjects
Status: COMPLETED
Conditions: Alzheimer Disease
Interventions: DRUG: AC-OLE-01-VA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Rectal Indomethacin Versus Intraperitoneal Lidocaine for Analgesia After Laparoscopic Cholecystectomy
Status: COMPLETED
Conditions: Post-Operative Pain
Interventions: DRUG: Indomethacin suppository|DRUG: Lidocaine 2% Injectable Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Hematoma Block as an Adjunct to Procedural Sedation for Forearm Fracture Reduction
Status: TERMINATED
Conditions: Forearm Fracture
Interventions: DRUG: Lidocaine|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Survey in a Population of Sickle Cell Disease Patients to Evaluate the Transition Between the Queen Fabiola Children Hospital and the CHU Brugmann Hospital, and the Quality of the Hospital Care Within the CHU Brugmann Hospital.
Status: COMPLETED
Conditions: Sickle Cell Disease
Interventions: OTHER: Survey
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Trichomonas Vaginalis Repeat Infections Among HIV Negative Women
Status: COMPLETED
Conditions: Vaginitis Trichomonal or Due to Trichomonas
Interventions: DRUG: MTZ 500 mg twice daily x 7 days|DRUG: MTZ 2 g
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sodium-glucose Transport 2 Inhibitors (SGLT2i) in HFrEF Patients
Status: RECRUITING
Conditions: Heart Failure|Reduced Ejection Fraction Heart Failure
Interventions: DRUG: Empagliflozin 10 MG|DRUG: Dapagliflozin 10 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study Investigating the Effect of Everolimus Monotherapy in Patients With Advanced Non-small Cell Lung Cancer (NSCLC)
Status: COMPLETED
Conditions: Non-small-cell Lung Carcinoma
Interventions: DRUG: RAD001
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gemcitabine - Oxaliplatin for Advanced Refractory Thyroid Cancer Patients: a Phase II Study
Status: TERMINATED
Conditions: Thyroid Cancer
Interventions: DRUG: gemcitabine -oxaliplatine combination
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Pembrolizumab With or Without Defactinib Following Chemotherapy as a Neoadjuvant and Adjuvant Treatment for Resectable Pancreatic Ductal Adenocarcinoma
Status: RECRUITING
Conditions: Resectable Pancreatic Ductal Adenocarcinoma (PDAC)|Pancreatic Ductal Adenocarcinoma
Interventions: DRUG: Pembrolizumab|DRUG: Defactinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of ICBT for Severe Health Anxiety in Clinical Psychiatry.
Status: COMPLETED
Conditions: Health Anxiety|Hypochondriasis|Illness Anxiety Disorder|Somatic Symptom Disorder|Severe Health Anxiety|Hypochondriacal Disorder, Unspecified
Interventions: BEHAVIORAL: Internet based Cognitive Behavioural Therapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Fecal Microbiota Transplantation to Relieve Symptoms of Irritable Bowel Syndrome Without Constipation
Status: RECRUITING
Conditions: Irritable Bowel Syndrome
Interventions: PROCEDURE: Fecal microbiota transplantation (FMT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Open Label Study Telmisartan and Amlodipine in Hypertension
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: telmisartan/amlodipine 40/5 mg fixed combination|DRUG: telmisartan/amlodipine 80/5 mg fixed combination
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Can Caudal Dexmedetomidine Provide Effective Analgesia?
Status: NOT_YET_RECRUITING
Conditions: Anesthesia|Local Anesthesia
Interventions: DRUG: Caudal Bupivacaine injection|DRUG: Caudal Dexmedetomidine Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of the Efficacy of Hippocampal Avoidance on the Cognitive Toxicity of Whole-Brain Radiation Therapy After Surgical Resection of Single Brain Metastasis of Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer|Brain Metastasis
Interventions: RADIATION: Radiation therapy Brain metastasis in breast cancer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Drug Eluting Balloons PTA in Infra-popliteal Arteries in Patients With Critical Limb Ischemia
Status: UNKNOWN
Conditions: Critical Limb Ischemia
Interventions: PROCEDURE: DEB PTA|PROCEDURE: Standard PTA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I Study of Autologous, Activated CD8(+) Lymphocytes Expanded In Vitro and Infused With or Without Recombinant Interleukin-2 to Patients With AIDS or Severe ARC
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Zidovudine|DRUG: Aldesleukin
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Peri-Articular Anaesthetic for Replacement of the Knee
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: DRUG: Liposomal bupivacaine|DRUG: Bupivacaine hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Does Active Parent Involvement in Deliberation and Choice Improve Medication Persistence for Their Child With ADHD
Status: COMPLETED
Conditions: Attention-Deficit/Hyperactivity Disorder (ADHD)
Interventions: BEHAVIORAL: Choice|BEHAVIORAL: Recommendation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Warm Patch Decrease Propofol Injection Pain
Status: COMPLETED
Conditions: Pain Syndrome|Propofol Infusion Syndrome|Injection Site Irritation
Interventions: DEVICE: Warming patch|DEVICE: Cotton patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Efficacy of Medical Students to Identify Pathological Lung Sound Over a Period of Time
Status: ENROLLING_BY_INVITATION
Conditions: Lung Sound
Interventions: OTHER: Identify pathological and not pathological lung sounds
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Gene Therapy For Children With Variant Late Infantile Neuronal Ceroid Lipofuscinosis 6 (vLINCL6) Disease
Status: COMPLETED
Conditions: Variant Late-Infantile Neuronal Ceroid Lipofuscinosis
Interventions: GENETIC: AT-GTX-501
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Interest of Stiripentol and Carbamazepine in the Treatment of Patients With Pharmacoresistant Focal Epilepsies
Status: COMPLETED
Conditions: Pharmacoresistant Focal Epilepsies
Interventions: DRUG: Stiripentol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Single and Repeat Dose Trial in Participants With Hepatic Impairment
Status: ACTIVE_NOT_RECRUITING
Conditions: Hepatic Impairment
Interventions: DRUG: GB1211|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study of Danirixin in Japanese Healthy Elderly Male Subjects
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: GSK1325756H|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Performance and Safety of the Aktiia Spot-check Optical Blood Pressure Monitoring Device at Wrist Against Double Auscultation
Status: NOT_YET_RECRUITING
Conditions: Hypertension
Interventions: DEVICE: Device under test evaluation against references
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Effect of Topical Treatment With Combigan Compared to Timolol and Brimonidine on Pupil Diameter
Status: UNKNOWN
Conditions: Healthy
Interventions: DRUG: Combigan (Combination of Brimonidine and Timolol)|DRUG: Timolol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Post-Discharge Risk-Based Management in Patients Undergoing High-Risk Elective Major Cancer Operations (PRS II)
Status: RECRUITING
Conditions: Surgery|Cancer
Interventions: PROCEDURE: Intensified post-discharge surveillance|PROCEDURE: Standard post-discharge surveillance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intraartecular Platelet Rich Plasma for Sacroiliitis
Status: COMPLETED
Conditions: Sacroiliitis
Interventions: OTHER: Ultrasound guided Sacroiliac intra-articular injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Zidovudine Plus Lamivudine in HTLV-I-associated Myelopathy: a Randomised Trial
Status: COMPLETED
Conditions: HTLV-I-associated Myelopathy
Interventions: DRUG: Zidovudine/lamivudine|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Individualized Selection of Chemotherapy in Patients With Advanced Pancreatic Carcinoma According to Therapeutic Targets
Status: COMPLETED
Conditions: Advanced Pancreatic Carcinoma
Interventions: DRUG: gemcitabine, or gemcitabine and capecitabine, or gemcitabine and erlotinib, or FOLFIRINOX, or FOLFOX, or FOLFIRI.|DRUG: Gemcitabine, Gemcitabine-Capecitabine, Gemcitabine-Erlotinib, FOLFOXIRI, FOLFOX, FOLFIRI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Concurrent Stereotactic Body Radiotherapy With Opdualag in Metastatic Uveal Melanoma
Status: RECRUITING
Conditions: Uveal Melanoma
Interventions: RADIATION: stereotactic body radiotherapy|DRUG: Immunotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Capsaicin-induced Muscle Pain in Humans
Status: COMPLETED
Conditions: Healthy
Interventions: PROCEDURE: Intramuscular capsaicin injection|PROCEDURE: Suprascapular nerve block|PROCEDURE: Local anesthetic infiltration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Dietary Supplementation on Gastrointestinal Barrier Function
Status: RECRUITING
Conditions: Intestinal Permeability
Interventions: DIETARY_SUPPLEMENT: plant derived phenolics|OTHER: Microcrystaline cellulose (MCC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Standard Chemotherapy Compared With High-Dose Chemotherapy Plus Peripheral Stem Cell Transplant in Treating Women With Advanced or Inflammatory Breast Cancer
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: DRUG: CMF regimen|DRUG: cyclophosphamide|DRUG: fluorouracil|DRUG: methotrexate|DRUG: tamoxifen citrate|DRUG: thiotepa|PROCEDURE: peripheral blood stem cell transplantation|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: A Nutritional Intervention in Police Officers
Status: SUSPENDED
Conditions: Overweight|Blood Pressure|Diabetes Mellitus, Type 2
Interventions: DIETARY_SUPPLEMENT: Plant-based diet|DIETARY_SUPPLEMENT: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Ultrasound-guided Transversus Abdominis Plane Block After Laparoscopic Bariatric Surgery
Status: UNKNOWN
Conditions: Nausea and Vomiting|Laparoscopic Bariatric Surgery
Interventions: DRUG: Ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: LifePearl-Doxo Pharmacokinetic (PK) Study
Status: COMPLETED
Conditions: HCC|Hepatocellular Carcinoma
Interventions: DEVICE: Chemoembolization|OTHER: Pharmacokinetics
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase Ib Study of Rocbrutinib in Combination With R-CHOP in Patients With Newly Diagnosed B-cell Non-Hodgkin Lymphoma
Status: RECRUITING
Conditions: B-cell Non-Hodgkin Lymphoma
Interventions: DRUG: Rocbrutinib|BIOLOGICAL: Rituximab|DRUG: Cyclophosphamide|DRUG: doxorubicin|DRUG: Vincristin|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating 13-valent Pneumococcal Conjugate Vaccine (13vPnC) in Children With Sickle Cell Disease
Status: COMPLETED
Conditions: Pneumococcal Conjugate Vaccine
Interventions: BIOLOGICAL: 13-valent Pneumoccocal Conjugate Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Use of Adiana Tubal Occlusive Devices in Women With Hydrosalpinx Prior to In Vitro Fertilization
Status: UNKNOWN
Conditions: Women Suffering From Unilateral or Bilateral Tubal Occlusion Due to Hydrosalpinx
Interventions: DEVICE: Adiana placement
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study on the Use of Tanakan® for Recovery of Neurological Impairment Following Ischaemic Stroke
Status: COMPLETED
Conditions: Stroke, Acute|Neurological Impairment
Interventions: DRUG: EGb761|DRUG: Placebo|DRUG: Acetylsalicylic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Serotonin Role on Brain Circuits Involved in Food Avoidance in Anorexia Nervosa
Status: RECRUITING
Conditions: Anorexia Nervosa
Interventions: OTHER: PET imaging using [11C]DASB radioligand.|BEHAVIORAL: Eye Tracker
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation and Comparison of Efficacy Between Extracorporeal Magnetic Innervation and High-intensity Kegel Exercise Regimen in Treatment of Stress Urinary Incontinence in Female
Status: UNKNOWN
Conditions: Stress Urinary Incontinence
Interventions: DEVICE: Peritron perineometer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: "Effects of Oral Citrulline on Protein Metabolism in Healthy Humans: a Prospective, Randomized, Double-blind , Cross-over Study" (Citrugrêle)
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: citrulline|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dose-Finding Trial to Evaluate the Safety and Immunogenicity of Cytomegalovirus (CMV) Vaccine mRNA-1647 in Healthy Adults
Status: COMPLETED
Conditions: Cytomegalovirus Infection
Interventions: BIOLOGICAL: mRNA-1647|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The ODYSSEY TRIAL Phase IV Trial Evaluating the Palliative Benefit of Pamidronate or Zoledronic Acid in Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Pamidronate|DRUG: Zoledronic acid|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cell-free Tumor DNA in Head and Neck Cancer Patients
Status: RECRUITING
Conditions: Head and Neck Cancer|Head and Neck Neoplasms|Head and Neck Squamous Cell Carcinoma|Oropharynx Cancer|Oropharynx Neoplasm|Oropharynx Carcinoma|Oral Cavity Cancer|Oral Cancer|Oral Neoplasm|Larynx Cancer|Larynx Carcinoma|Larynx Neoplasm|Nasopharyngeal Carcinoma|Nasopharyngeal Cancer|Nasopharynx Neoplasm|Hypopharynx Cancer|Hypopharynx Neoplasm|Hypopharynx Carcinoma|Sinonasal Carcinoma|Thyroid Carcinoma|Thyroid Cancer|Thyroid Neoplasms|Salivary Gland Cancer|Salivary Gland Neoplasms|Salivary Gland Carcinoma|Sinonasal Cancer|Sinonasal Neoplasm
Interventions: DIAGNOSTIC_TEST: Liquid biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Accelerating the Implementation of a Breast and Cervical Cancer Screening and HPV Vaccination Intervention
Status: NOT_YET_RECRUITING
Conditions: Cancer Prevention
Interventions: BEHAVIORAL: Salud en Mis Manos - Dissemination and Implementation Assistance|BEHAVIORAL: Salud en Mis Manos- Usual Implementation Practice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Clinical Trial to Assess the Efficacy and Safety of JMT103 in Patients With Refractory HCM
Status: UNKNOWN
Conditions: Hypercalcemia of Malignancy
Interventions: DRUG: JMT103
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of the Effect of Low-Molecular-Weight Heparin (LMWH) Versus Warfarin on Mortality in the Long-Term Treatment of Proximal Deep Vein Thrombosis (DVT) (Main LITE Study)
Status: COMPLETED
Conditions: Thrombosis|Thromboembolism|Venous Thrombosis
Interventions: DRUG: Tinzaparin sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cardiac Responsiveness Assessment by CO2
Status: UNKNOWN
Conditions: VCO2 Variation in Intensive Care as a Marker of Fluid Responsiveness|Cardiac Index Variation Transpulmonary Thermodilution in Patients on Controlled Ventilation With Shock
Interventions: DIAGNOSTIC_TEST: impact of fluid challenge on the cardiac index and CO2 respiratory parameters analysis (VCO2, EtCO2)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Can a Subcostal Nerve Block Add Benefit to a Lateral Femoral Cutaneous Nerve Block for Open Hip Surgery
Status: UNKNOWN
Conditions: Anesthesia, Local
Interventions: PROCEDURE: Lateral Cutaneous Nerve Of The Thigh Nerve Block Using Local Anaesthetic|PROCEDURE: Subcostal Nerve Block Using Local Anaesthetic
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fentanyl Test and A Short OSAS Screening Scale for Severe Obstructive Sleep Apnea
Status: COMPLETED
Conditions: Obstructive Sleep Apnea
Interventions: OTHER: the short OSAS scale|DIAGNOSTIC_TEST: fentanyl test
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Influence of Aromatase Inhibition on Hepatic- and Cardiac Function in Severe Obese Men
Status: COMPLETED
Conditions: Obesity
Interventions: DRUG: Letrozole|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Can Birthly, an Online Childbirth Education Platform, Reduce Pregnancy-related Anxiety Compared to Usual Care
Status: COMPLETED
Conditions: Pregnancy, High Risk
Interventions: OTHER: Birthly|OTHER: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Aromatase Inhibitors in the Treatment of Male Infertility
Status: TERMINATED
Conditions: Obesity|Oligospermia
Interventions: DRUG: Anastrozole|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: S0433 Iodine I 131 Tositumomab, Rituximab, and Combination Chemotherapy in Treating Older Patients With Stage II, Stage III, or Stage IV Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: BIOLOGICAL: rituximab|DRUG: cyclophosphamide|DRUG: doxorubicin hydrochloride|DRUG: prednisone|DRUG: vincristine sulfate|RADIATION: tositumomab and iodine I 131 tositumomab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Massage, Oxidative and Antioxidant Enzymes in Hemodialysis Patients With Restless Legs Syndrome(RLS)
Status: COMPLETED
Conditions: Renal Failure Chronic|Restless Legs Syndrome
Interventions: OTHER: Massage
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Medical and Surgical Treatment for Idiopathic Granulomatous Mastitis
Status: UNKNOWN
Conditions: Granulomatous Mastitis
Interventions: DRUG: Hydrocortisone Butyrate|PROCEDURE: extended excision
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Concordance of Three Imaging Methods by Dynamic CT, Contrast Ultrasound and CT Angiography in the Characterization of Endoleaks in Patients With an Aortic Endoprosthesis
Status: RECRUITING
Conditions: Aortic Diseases
Interventions: OTHER: three-phase CT angiography|OTHER: CEUS ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Two Year Developmental Follow-up for PREMOD2 Trial (Premature Infants Receiving Milking or Delayed Cord Clamping)
Status: RECRUITING
Conditions: Neurodevelopmental Abnormality
Interventions: PROCEDURE: Randomized to Umbilical Cord Milking at birth|PROCEDURE: Randomized to Delayed Cord Clamping at birth
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Randomized Evaluation of D-dimer Guiding dUration of Oral antiCoagulation thErapy
Status: UNKNOWN
Conditions: Valve Heart Disease|Anticoagulants; Increased
Interventions: DRUG: Warfarin Sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluating the Efficacy and Safety of Bemcentinib in Patients With Myelodysplastic Syndromes
Status: COMPLETED
Conditions: Acute Myeloid Leukemia|High-risk Myelodysplastic Syndrome|Low-risk Myelodysplastic Syndrome
Interventions: DRUG: Bemcentinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A PiLot ClinicaL TrIal of ParicAlcitol for ChroNiC PancrEatitis
Status: RECRUITING
Conditions: Chronic Pancreatitis
Interventions: DRUG: Paricalcitol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PET Study to Determine Muscarinic Receptor Occupancy in Lungs After Inhalation of AZD2115 and Tiotropium
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: AZD2115|DRUG: SPIRIVA|RADIATION: [11C]AZ13754366
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Sphincter-preserving Surgery After Preoperative Treatment of Ultra-low Rectal Carcinoma
Status: COMPLETED
Conditions: Rectal Cancer
Interventions: RADIATION: High-Dose radiotherapy|RADIATION: Chemo-radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Immune Response and Safety of Two Doses of GSK Biologicals' HRV Liquid Vaccine in Healthy Infants.
Status: COMPLETED
Conditions: Infections, Rotavirus|Rotavirus Vaccines
Interventions: BIOLOGICAL: Rotarix™|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Fluvoxamine Administration in Moderate SARS-CoV-2 (COVID-19) Infected Patients
Status: COMPLETED
Conditions: Covid19
Interventions: DRUG: Placebo|DRUG: Fluvoxamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ADenosine Following Pulmonary Vein Isolation to Target Dormant Conduction Elimination: the ADVICE Trial
Status: COMPLETED
Conditions: Paroxysmal Atrial Fibrillation|Pulmonary Vein Isolation|Dormant Pulmonary Vein Conduction
Interventions: PROCEDURE: Additional ablation until elimination of dormant conduction|PROCEDURE: No additional ablation|PROCEDURE: Registry group|PROCEDURE: Usual medical care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Gingival Thickness Using Colored Periodontal Probe
Status: RECRUITING
Conditions: Gingival Phenotype
Interventions: DIAGNOSTIC_TEST: colored periodontal probes (CPP)|DIAGNOSTIC_TEST: standard periodontal probes (SPP)|DIAGNOSTIC_TEST: transgingival sounding with an endodontic file
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Improving the Quality of End-of-Life Communication for Patients With Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Pulmonary Disease|COPD|Chronic Bronchitis|Emphysema
Interventions: BEHAVIORAL: Audit and Feedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Targeting the Gut Microbiome for Prader-Willi Syndrome Treatment
Status: COMPLETED
Conditions: Prader-Willi Syndrome
Interventions: DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: Probiotic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Dance and Tai Chi on Balance and Wellbeing on Healthy Adults
Status: NOT_YET_RECRUITING
Conditions: General Population
Interventions: OTHER: Dance|OTHER: Tai Chi
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Post-marketing Evaluation of Mudan Granule Intervention on Type 2 Diabetic Peripheral Neuropathy
Status: UNKNOWN
Conditions: Diabetic Peripheral Neuropathy Type 2
Interventions: DRUG: Mudan granule|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Examining the Effect of Mental Health Disorders on Vascular Function and Exercise Tolerance
Status: COMPLETED
Conditions: Mental Health Disorders
Interventions: DIETARY_SUPPLEMENT: PTSD/GAD Antioxidant|DIETARY_SUPPLEMENT: PTSD/GAD Placebo|DIETARY_SUPPLEMENT: Healthy Control Antioxidant|DIETARY_SUPPLEMENT: Healthy Control Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Primary Non-surgical Endodontic Therapy on Glycaemic Control in Type 2 Diabetic Patients With Asymptomatic Apical Periodontitis
Status: COMPLETED
Conditions: Diabete Type 2|Apical Periodontitis
Interventions: PROCEDURE: Primary endodontic treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial Using the Proteolytic Fraction P1G10 From V. Cundinamarcensis to Heal Diabetic Foot Ulcer
Status: COMPLETED
Conditions: Diabetic Foot|Neuropathy, Diabetic|Foot Ulcer
Interventions: DRUG: Hydrogel treatment|DRUG: P1G10
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Gestional Trophoblastic Neoplasia Ultrasound Assessment: Titanium Study
Status: RECRUITING
Conditions: Describe Typical Gray Scale/Color Doppler Ultrasound Features of Gestational Trophoblastic Neoplasia at the US Examination|To Assess if There Are Differences at the Baseline US Scan Between Low-risk and High-risk Patients|To Identify Ultrasound Predictors of Resistance to First-line Single Drug Chemotherapy in Low-risk GTN Patients|To Investigate if Machine Learning (ML) Algorithms (Radiomics, Deep Neural Networks (DNN), and Other Machine Learning Algorithms
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Insulin Detemir and Insulin Glargine on Blood Glucose Control in Subjects With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: insulin detemir|DRUG: insulin glargine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Abilify® Tablet(Aripiprazole) as an Adjunctive Treatment in the Bipolar Depression
Status: RECRUITING
Conditions: Depression, Bipolar
Interventions: DRUG: Abilify 2, 5, 10, 15mg (Tablet)|DRUG: Placebo of Abilify 2, 5, 10, 15mg (Tablet)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT