pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Dynamic Laryngeal Opening for Bilateral Vocal Fold Paralysis by an Implanted Stimulator
Status: COMPLETED
Conditions: Vocal Cord Paralysis
Interventions: DEVICE: pacemaker
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Grass Pollen Immunotherapy Using a Cluster Regime for Seasonal Rhinitis and Asthma
Status: COMPLETED
Conditions: Rhinitis, Allergic, Seasonal
Interventions: BIOLOGICAL: Subcutaneous Alutard SQ grass pollen (Phleum pratense)|PROCEDURE: Venepuncture: 20 ml blood sample taken on 2 separate visits
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Modified Paramedic Sagittal vs. Transverse TMQLB
Status: COMPLETED
Conditions: Nerve Block
Interventions: PROCEDURE: transverse scan, in-plane, posterior-anterior TMQLB|PROCEDURE: paramedian sagittal scan, in-plane, caudal-cranial TMQLB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Efficacy and Safety of Hou Gu Mi Xi in Patients With Spleen Qi Deficiency and Non-organic Gastrointestinal Disorders
Status: COMPLETED
Conditions: Gastrointestinal Disease
Interventions: DIETARY_SUPPLEMENT: Hou Gu Mi Xi|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Exercise and Arterial Stiffness in Systemic Lupus Erythematosus
Status: COMPLETED
Conditions: Systemic Lupus Erythematosus
Interventions: BEHAVIORAL: Aerobic exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intubation and Ventilation Skill Training Using Modified Peyton's Four-Step Approach
Status: COMPLETED
Conditions: Educational Problems
Interventions: OTHER: Classic Peyton's Four-Step Approach|OTHER: Modified Peyton's Four-Step Approach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Catheters Dysfunction Rate After Instillation of Ethanol 60% Lock Solution in Tunneled Silicone Catheter of Chronic Hemodialysis Patients
Status: TERMINATED
Conditions: End Stage Renal Failure, Hemodialysis
Interventions: DRUG: Ethanol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: |Primary Purpose: TREATMENT
Clinical trial: Ketorolac Sublingual vs. Fentanyl Intranasal in Pain Control for Bilateral Myringotomy and Tubes (BMT) Placement in Children
Status: UNKNOWN
Conditions: Pain, Postoperative|Otitis Media
Interventions: DRUG: Ketorolac|DRUG: Fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Combined Metformin and Cabergoline in Comparison With Metformin Only Therapy on Ovarian and Hormonal Activities in Iraqi Patients With PCOS
Status: COMPLETED
Conditions: Polycystic Ovary Syndrome
Interventions: DRUG: Metformin Hydrochloride 500 MG|DRUG: Cabergoline 0.5 MG|DRUG: Metformin Hydrochloride 500 MG + Cabergoline 0.5 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Pant Type Absorbing Urinary Incontinence Products
Status: COMPLETED
Conditions: Urinary Incontinence
Interventions: DEVICE: RH1 (low waist)|DEVICE: Reference variant 1 (low waist)|DEVICE: RC2 (high waist)|DEVICE: Reference variant 2 (high waist)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Study of Combination Use of Melatonin Receptor Agonist for Dose Reduction or Interruptions of Benzodiazepine (BZD) and Non-BZD Hypnotics on Chronic Insomnia
Status: COMPLETED
Conditions: Chronic Insomnia
Interventions: DRUG: Ramelteon 8mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Improving Pain Management After Total Shoulder Replacement Using Bupivacaine Liposome
Status: WITHDRAWN
Conditions: Osteoarthritis of the Shoulder|Shoulder Pain|Pain, Postoperative
Interventions: DRUG: Bupivacaine Liposome Injection|OTHER: Standard Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Financial and Mental Health: Exploratory Research
Status: COMPLETED
Conditions: Financial Difficulties
Interventions: BEHAVIORAL: One-on-one financial counseling|BEHAVIORAL: Peer support group|BEHAVIORAL: Supported access to mainstream banking services|BEHAVIORAL: A matched savings account
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Using Placental Membranes on Healing and Post-op Pain After Gum Surgery
Status: UNKNOWN
Conditions: Pain, Postoperative|Gingival Diseases
Interventions: BIOLOGICAL: amnion-chorion membrane|PROCEDURE: Sutures
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Autologous Fibroblasts in the Treatment of Severe Facial Acne Scarring
Status: COMPLETED
Conditions: Acne Scarring of the Face
Interventions: BIOLOGICAL: Autologous Human Fibroblasts (azficel-T)|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Success Rates of Femoral Artery Catheterization
Status: COMPLETED
Conditions: Pulmonary Disease|Electrolyte Disorder|Metabolic Disease|Sepsis
Interventions: PROCEDURE: Femoral artery catheterization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: PKC412 in Participants With Acute Myeloid Leukemia or With Myelodysplastic Syndrome (CPKC412A2104 Core); and PKC412 in Participants With Acute Myeloid Leukemia or With Myelodysplastic Syndrome With Either Wild Type or Mutated FMS-like Tyrosine Kinase 3 (FLT3) (CPKC412A2104E1 and CPKC412A2104E2)
Status: COMPLETED
Conditions: Acute Myeloid Leukemia|Myelodysplastic Syndromes
Interventions: DRUG: Itraconazole|DRUG: PKC412
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Wire Instrumentation Using Radiofrequency Energy to Impact Transseptal Efficiency
Status: COMPLETED
Conditions: Atrial Fibrillation|Atrial Flutter
Interventions: DEVICE: Baylis Versacross RF wire|DEVICE: Baylis RF needle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: STP.168 Clinical Study Protocol Parakeet
Status: ACTIVE_NOT_RECRUITING
Conditions: Parathyroid; Anomaly|Parathyroid Dysfunction|Hyperparathyroidism|Parathyroid Gland Adenoma
Interventions: DEVICE: Parakeet:The Parakeet Rapid Parathyroid Testing Kit is a rapid immunoassay designed to detect Parathormone (PTH) in a test sample.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Evaluation of Asymptomatic Coronary Atherosclerotic Disease Among People of Kalamazoo, MI
Status: UNKNOWN
Conditions: Coronary Artery Disease|Atherosclerosis
Interventions: PROCEDURE: Computed Tomography (CT) Scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Thyroid Hormone Replacement on Fatigability in Untreated Older Adults With Subclinical Hypothyroidism
Status: COMPLETED
Conditions: Thyroid Dysfunction|Mental Fatigue|Fatigue
Interventions: DRUG: Levothyroxine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Bosentan for Intermittent Claudication in Peripheral Arterial Disease
Status: COMPLETED
Conditions: Peripheral Arterial Disease
Interventions: DRUG: Bosentan|DRUG: Antiaggregant therapy|DRUG: Statins|DRUG: Antihypertensive therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Supraclavicular, Suprascapular, and Interscalene Nerve Blocks for Outpatient Shoulder Surgery
Status: COMPLETED
Conditions: Pain, Postoperative|Pain|Shoulder Joint|Pathologic Processes
Interventions: PROCEDURE: Brachial plexus nerve block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: the Effect of Misoprostol on Intra-operative Blood Loss During Myomectomy Operation
Status: UNKNOWN
Conditions: Myoma;Uterus|Blood Loss
Interventions: DRUG: Misoprostol|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: An Open-Label Study of the Safety and Efficacy of Cidofovir for the Treatment of Relapsing Cytomegalovirus Retinitis in Patients With AIDS
Status: COMPLETED
Conditions: Cytomegalovirus Retinitis|HIV Infections
Interventions: DRUG: Cidofovir|DRUG: Probenecid
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intravenous Treatments Used in Medication Overuse Headache Bridge Treatment
Status: ACTIVE_NOT_RECRUITING
Conditions: Medication Overuse Headache
Interventions: OTHER: Intravenous hydration|OTHER: Intravenous prednisolone|OTHER: Intravenous lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Can Pre-operative Anemia be Timely Identified and Optimized in Patients Awaiting Primary Arthroplasty Surgery? A Randomized Clinical Trial
Status: NOT_YET_RECRUITING
Conditions: Anemia|Hip Osteoarthritis
Interventions: DIAGNOSTIC_TEST: Anemia testing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Personalized Indications for CBT and Antidepressants in Treating Depression
Status: RECRUITING
Conditions: Major Depressive Disorder|Persistent Depressive Disorder
Interventions: BEHAVIORAL: Cognitive Behavioral Therapy|DRUG: Pharmacotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Carboplatin and Pemetrexed in Recurrent Platinum Sensitive Ovarian Cancer
Status: COMPLETED
Conditions: Ovarian Cancer|Peritoneal Cancer|Fallopian Tube Cancer
Interventions: DRUG: Carboplatin|DRUG: Pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Technology-Supported Hand Strengthening and Stretching Exercises in Patients With Rheumatoid Arthritis
Status: UNKNOWN
Conditions: Rheumatoid Arthritis
Interventions: BEHAVIORAL: Digital exercise group|OTHER: General Home Hand Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Serial Ultrasound of Solid Tumor Lesions to Detect Early Response to Cancer Immunotherapy
Status: RECRUITING
Conditions: Solid Tumor
Interventions: DIAGNOSTIC_TEST: Doppler ultrasound|DIAGNOSTIC_TEST: Long Ensemble Angular-coherence Doppler [LEAD] ultrasound|DIAGNOSTIC_TEST: Contrast-enhanced ultrasound (CEUS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Follicular Flushing in Patients With Mono-follicular Growth Undergoing In Vitro Fertilization
Status: COMPLETED
Conditions: Invitro Fertilization|Diminished Ovarian Reserve|Oocyte
Interventions: BEHAVIORAL: direct follicular aspiration|BEHAVIORAL: follicular flushing
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Influence of SRP With MM on the Composition and Functional Characteristics of Subgingival Microbiome Communities
Status: RECRUITING
Conditions: Periodontitis
Interventions: PROCEDURE: SRP + MM|PROCEDURE: Scaling and Root Planing (SRP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Efficacy & Safety, of Metadoxine (MG01CI) Extended Release in Attention-Deficit Hyperactivity Disorder (ADHD)
Status: COMPLETED
Conditions: ADHD
Interventions: DRUG: Metadoxine (MG01CI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Prospectively Validate Blood Markers Associated With Differences in Efficacy of Neoadjuvant Therapy for NSCLC
Status: NOT_YET_RECRUITING
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: Chemotherapy combined with immunotherapy|DRUG: Chemotherapy only
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Oxybutynin and Omega-3 for OAB (Overactive Bladder)
Status: TERMINATED
Conditions: Overactive Bladder
Interventions: DRUG: Omega 3 Fatty Acid|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Between ThinSeed™ and OncoSeed™ for Permanent Prostate Brachytherapy
Status: UNKNOWN
Conditions: Prostate Cancer
Interventions: DEVICE: RapidStrand seeds for use with 18g needle|DEVICE: ThinStrand
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, and Effectiveness of Intramuscular Injection of CELZ-201-DDT for the Treatment of Chronic Lower Back Pain
Status: RECRUITING
Conditions: Chronic Low-back Pain|Degenerative Disc Disease
Interventions: DRUG: CELZ-201-DDT|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Immediate and Chronic Effects of Whole-Body Vibration on Neuromuscular Performance and Postural Control in Elderly
Status: COMPLETED
Conditions: Neuromuscular Performance and Balance
Interventions: OTHER: WBV exercise program|OTHER: Sham WBV exercise program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rituximab Trial for Pediatric Nephrotic Syndrome
Status: UNKNOWN
Conditions: Steroid Resistant Nephrotic Syndrome|Steroid Dependent Nephrotic Syndrome
Interventions: DRUG: Rituximab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Combined Treatment for Patients With Comorbid Substance Use Disorders and Post-traumatic Stress Disorder (PTSD): an Integration of Cognitive-behavioral Treatment (CBT) and Trauma-focused Structured Writing Therapy
Status: COMPLETED
Conditions: Substance-Related Disorders|Stress Disorders, Post-Traumatic
Interventions: BEHAVIORAL: CBT for SUD|BEHAVIORAL: Structured writing therapy for PTSD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of an Air Purifying Device (PureNight) on Sleep Quality in Obstructive Lung Disease
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: OTHER: HEPA filtration|OTHER: SHAM
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Dose Response Relationship Between Fat Ingestion and Metabolism
Status: NOT_YET_RECRUITING
Conditions: Glucose Tolerance Impaired
Interventions: OTHER: 20% fat meal|OTHER: 40% fat meal|OTHER: 60% fat meal|OTHER: 80% fat meal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Innovative Intermittent Preventive Treatment Approaches to Reduce Malaria Burden in School-age Children in Burkina Faso
Status: RECRUITING
Conditions: Malaria
Interventions: DRUG: Sulphadoxine-Pyrimethamine/Amodiaquine|DRUG: Dihydroartemisinin/Piperaquine (DP) plus Ivermectin (IVM)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of HMPL-689 in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: HMPL-689|DRUG: HMPL-689 placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Nonmyeloablative Haploidentical Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation for Sickle Cell Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Sickle Cell Disease
Interventions: PROCEDURE: haploidentical stem cell transplant|DRUG: Sirolimus|DRUG: Alemtuzumab|DRUG: Pentostatin|DRUG: Cyclophosphamide|DRUG: Hydroxyurea|DRUG: Filgrastim
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of NGX-4010 With the Use of Open Label Lidocaine (2.5%)/Prilocaine (2.5%) Cream for the Treatment of Postherpetic Neuralgia (PHN)
Status: COMPLETED
Conditions: Postherpetic Neuralgia
Interventions: DRUG: capsaicin 8%|DRUG: Lidocaine (2.5%)/Prilocaine (2.5%) Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Using Transorbital Alternating Current Stimulation for People With Glaucoma
Status: COMPLETED
Conditions: Glaucoma
Interventions: DEVICE: rtACS Stimulation|DEVICE: Sham Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Buspirone for Early Satiety and Symptoms of Gastroparesis
Status: COMPLETED
Conditions: Gastroparesis
Interventions: DRUG: Buspirone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Bevacizumab in Combination With Chemotherapy for Treatment of Osteosarcoma
Status: COMPLETED
Conditions: Osteosarcoma|Malignant Fibrous Histiocytoma (MFH) of Bone
Interventions: BIOLOGICAL: Bevacizumab|DRUG: Cisplatin|DRUG: Doxorubicin|DRUG: Methotrexate|DRUG: Ifosfamide|DRUG: etoposide|PROCEDURE: Surgery|RADIATION: Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: "COMBO-KEY" - A Home Visiting and Phone Coaching Programme to Promote Stroke Survivors' Recovery
Status: COMPLETED
Conditions: Stroke
Interventions: BEHAVIORAL: COMBO-KEY
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Auto Stem Cell Transplant for Lymphoma Patients
Status: RECRUITING
Conditions: Non-Hodgkin Lymphoma|Hodgkin Lymphoma
Interventions: DRUG: Etoposide|DRUG: BCNU|DRUG: AraC|DRUG: Melphalan|PROCEDURE: Peripheral blood stem cell transplantation|BIOLOGICAL: G-CSF|DRUG: Cyclophosphamide|RADIATION: Total Body Irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Short Duration Versus Fourteen Days Antibiotic in Common Bile Duct Cholangitis
Status: COMPLETED
Conditions: Acute Cholangitis|Common Bile Duct Calculi
Interventions: OTHER: Short duration of antibiotic|OTHER: Standard treatment of antibiotic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Evaluate the Safety and Efficacy of IM21 CAR-T Cells in the Treatment of Elderly Patients With Relapsed or Refractory Multiple Myeloma
Status: UNKNOWN
Conditions: Multiple Myeloma
Interventions: DRUG: IM21 CAR-T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neutral and Positive Attention Bias Modification Training for Young Adults With Depressive Symptoms
Status: COMPLETED
Conditions: Depressive Disorder
Interventions: BEHAVIORAL: Neutral ABMT|BEHAVIORAL: Positive ABMT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Adrenaline Infiltration on Surgical Field of View in Endoscopic Sinus Surgery
Status: COMPLETED
Conditions: Intraoperative Bleeding
Interventions: DRUG: Epinephrin|DRUG: 1% lidocaine with epinephrin 1:100,000|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Evaluate Efficacy, Safety, and Tolerability of KX-826 in Male Subjects With Androgenetic Alopecia
Status: COMPLETED
Conditions: Alopecia|Male Pattern Hair Loss
Interventions: DRUG: KX- 826 dosed at 2.5mg|DRUG: KX-826 dosed at 5mg|DRUG: KX-826 dosed at 5mg|DRUG: Matching placebo to KX-826
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Identification of Markers (Klotho-FGF23 Axis) as Determinant in the Evolution of Arterial Stiffness During the First Year of Renal Transplant
Status: COMPLETED
Conditions: Renal Transplant
Interventions: BIOLOGICAL: Biological sample|PROCEDURE: Non invasive Arterial investigations|PROCEDURE: Abdominal tomodensitometry
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Scalable Digital Delivery of Evidence-based Training for Professionals to Maximize Treatment Rates of OUD in Families
Status: COMPLETED
Conditions: Community Reinforcement And Family Training|Family Health|Substance-Related Disorders
Interventions: BEHAVIORAL: Behavioral: Digital Tutorial Overview|BEHAVIORAL: Behavioral: Training Materials|BEHAVIORAL: Behavioral: Feedback and Coaching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Cognitive Remediation and Functional Skills Training in Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder
Interventions: BEHAVIORAL: Cognitive Remediation|BEHAVIORAL: FAST
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of SARS-CoV-2 Vaccination in Liver Transplant Recipients
Status: COMPLETED
Conditions: SARS-CoV-2 Vaccination|Liver Transplantation
Interventions: DIAGNOSTIC_TEST: Immunoassay, by ECLIA, for the quantitative in vitro determination of antibodies (including IgG) to the SARS - CoV - 2 spike protein (S) anti-RBD (receptor-binding domain) in serum and plasma samples.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Clinical Trial to Examine the Efficacy of a Supplement to Support Healthy Hair and Skin
Status: ACTIVE_NOT_RECRUITING
Conditions: Hair Thinning|Hair Loss
Interventions: DIETARY_SUPPLEMENT: Live Conscious Beyond Collagen|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Copanlisib With Ibrutinib for Patients With Recurrent/ Refractory Primary Central Nervous System Lymphoma (PCNSL)
Status: ACTIVE_NOT_RECRUITING
Conditions: Refractory/Recurrent Primary Central Nervous System Lymphoma (PCNSL)
Interventions: DRUG: Ibrutinib|DRUG: Copanlisib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hematopoietic Stem Cell Support in Patients With Autoimmune Bullous Skin Disorders
Status: TERMINATED
Conditions: Pemphigus
Interventions: BIOLOGICAL: Hematopoietic stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Postoperative Delirium After Total Knee Arthroplasty Under Regional Anesthesia
Status: UNKNOWN
Conditions: Postoperative Delirium
Interventions: DRUG: Propofol|DRUG: Dexmedetomidine|DRUG: Fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Compare to the Safety of Efavirenz and Nevirapine in Treating HIV Positive Patients With Mild Baseline Liver Function Test Impairment, and/or Hepatitis B or Hepatitis C Co-infection
Status: UNKNOWN
Conditions: HIV Infections|Liver Toxicity|Hepatitis Co-infection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: 90 Y-BC8-DOTA Monoclonal Antibody, Fludarabine Phosphate, and Total-Body Irradiation Followed by Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Multiple Myeloma
Status: COMPLETED
Conditions: Plasma Cell Myeloma|Refractory Plasma Cell Myeloma
Interventions: PROCEDURE: Allogeneic Hematopoietic Stem Cell Transplantation|DRUG: Cyclosporine|DRUG: Fludarabine Phosphate|DRUG: Mycophenolate Mofetil|PROCEDURE: Peripheral Blood Stem Cell Transplantation|RADIATION: Total-Body Irradiation|RADIATION: Yttrium Y 90 Anti-CD45 Monoclonal Antibody BC8
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pulpotomy in Primary Molars Treated With Premixed Bio-ceramic MTA Versus Formocresol
Status: UNKNOWN
Conditions: Caries
Interventions: DRUG: Formocresol|DRUG: Premixed bioceramic MTA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mitiglinide in Combination With Metformin vs. Metformin Alone in Patients With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: placebo for mitiglinide|DRUG: mitiglinide|DRUG: mitiglinide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Biodegradable Stents in Lung Transplantation
Status: COMPLETED
Conditions: Lung Transplantation
Interventions: DEVICE: SX-ELLA Stent Degradable DV Bronchial (DV Stent)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimal Dosing of Vancomycin in an Adult Population of Hemato-oncology
Status: UNKNOWN
Conditions: Vancomycin|Hematologic Malignancies|Febrile Neutropenia
Interventions: OTHER: Additional blood sample
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of Relative Bioavailability of Mobic Manufactured in China in Comparison With Mobic Manufactured in Germany in Chinese Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Mobic, China, 7.5 mg|DRUG: Mobic, Germany, 7.5 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Dexamethasone on Low Dose Interscalene Brachial Plexus Block
Status: COMPLETED
Conditions: Shoulder Surgery|Nerve Block
Interventions: DRUG: Systemic Dexamethasone|DRUG: Perineural dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Opposing Step-by-step Insulin Reinforcement to Intensified Strategy
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Insulin Glargine|DRUG: Insulin Glulisine|DRUG: Metformin|DRUG: insulin secretagogue
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: P3 Study to Evaluate Efficacy and Safety of AMG 531 in Thrombocytopenic Japanese Subjects With Immune (Idiopathic) Thrombocytopenic Purpura
Status: COMPLETED
Conditions: Idiopathic Thrombocytopenic Purpura
Interventions: DRUG: Placebo|DRUG: AMG 531
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SWOG-9416: Chemotherapy, Radiation Therapy, and Surgery in Treating Patients With Stage III Non-small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DRUG: cisplatin|DRUG: etoposide|PROCEDURE: conventional surgery|RADIATION: low-LET cobalt-60 gamma ray therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Tislelizumab for Locally Advanced Non-Small Cell Lung Cancer Following Neoadjuvant Chemotherapy Plus Tislelizumab ± Bevacizumab and Definitive Concurrent Chemoradiation Therapy
Status: RECRUITING
Conditions: Stage III Non-small Cell Lung Cancer
Interventions: DRUG: Neoadjuvant chemo-immunotherapy|DRUG: Bevacizumab|RADIATION: Radiotherapy|DRUG: Tislelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Continuous Arterial Spin Labeling (CASL) MRI for Monitoring and Prediction of Drug Therapy in Alzheimers Disease (AD)
Status: UNKNOWN
Conditions: Alzheimer's Disease
Interventions: DRUG: Reminyl retard
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Vitamin D and Inflammatory Cytokine Levels After Acute Myocardial Infraction (MI)
Status: UNKNOWN
Conditions: Acute Coronary Syndrome|Cytokines
Interventions: DRUG: Vitamin D
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Non-invasive Optical Angiography in Age-related Macular Degeneration
Status: RECRUITING
Conditions: Age Related Macular Degeneration
Interventions: OTHER: Non-invasive OCT based optical angiography|OTHER: Oxymap T1|OTHER: OCT|OTHER: FLA/ICG angiography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Impact of Alna® Ocas® on Nocturia in Patients With Lower Urinary Tract Symptoms Suggestive of Benign Prostatic Hyperplasia (LUTS/BPH)
Status: COMPLETED
Conditions: Prostatic Hyperplasia
Interventions: DRUG: ALNA®OCAS®
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluating the Impact of Including Virtual Dietary Education Within an Electronic Irritable Bowel Syndrome Pathway
Status: RECRUITING
Conditions: IBS - Irritable Bowel Syndrome
Interventions: OTHER: virtually administered dietitian consults for IBS patients.|OTHER: IBS Group Online Session
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study to Assess if Scratching the Lining of the Womb Prior to IVF Treatment Increases the Chances of Pregnancy
Status: COMPLETED
Conditions: Infertility
Interventions: PROCEDURE: Endometrial biopsy|DEVICE: Transvaginal ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Combined Seed Extracts of Cassia Obtusifolia Linne and Foeniculum Vulgare Mill in Patients With Chronic Constipation
Status: COMPLETED
Conditions: Chronic Constipation
Interventions: DIETARY_SUPPLEMENT: The combined seed extracts of Cassia obtusifolia Linne and Foeniculum vulgare Mill|DIETARY_SUPPLEMENT: Placebo group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Test the Safety, Tolerability, and Blood Levels of UCB0022 in Healthy Participants and Participants With Parkinson's Disease
Status: COMPLETED
Conditions: Healthy Study Participants|Parkinson's Disease
Interventions: DRUG: UCB0022|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Interfascial Blocks Executed by Novice Operators in a Simulator Model: a Comparison of Two Types of Needles
Status: COMPLETED
Conditions: Anesthesia
Interventions: DEVICE: Ultraplex 360(Braun)|DEVICE: STIMUPLEX D SH, 30°(Braun)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Photobiomodulation and New Restorative Material for Teeth With MIH on Control of Hypersensitivity and Longevity
Status: NOT_YET_RECRUITING
Conditions: Hypomineralization Molar Incisor|Hypersensitivity Dentin
Interventions: PROCEDURE: Photobiomodulation + Restoration with Self-cure Composite Resin|PROCEDURE: Restoration with Self-cure Composite Resin|PROCEDURE: Photobiomodulation + Restoration with Photopolymerizable Bulk-fill Composite Resin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Mesenchymal Stem Cells Associated With Chronic Pancreatitis Pain
Status: RECRUITING
Conditions: Chronic Pancreatitis|Chronic Pain
Interventions: DRUG: Mesenchymal Stem Cells|OTHER: Other: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pazopanib Hydrochloride With or Without Bicalutamide in Treating Patients With Prostate Cancer That Did Not Respond to Hormone Therapy
Status: COMPLETED
Conditions: Hormone-Resistant Prostate Cancer|Recurrent Prostate Carcinoma
Interventions: DRUG: Bicalutamide|OTHER: Laboratory Biomarker Analysis|DRUG: Pazopanib Hydrochloride|OTHER: Pharmacological Study
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diabetes Companion App for Adults With Diabetes and Their Carers
Status: RECRUITING
Conditions: Diabetes|Diabetes Mellitus, Type 2|Diabetes Mellitus|Diabetes Type 2
Interventions: OTHER: GLOW
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Clinical Trial to Evaluate the Safety and Immunogenicity of Synthetic DNAs Encoding NP-GT8 and IL-12, With or Without a TLR-agonist-Adjuvanted HIV Env Trimer 4571 Boost, in Adults Without HIV
Status: ACTIVE_NOT_RECRUITING
Conditions: HIV Infections
Interventions: BIOLOGICAL: sD-NP-GT8 DNA|BIOLOGICAL: IL-12 DNA|BIOLOGICAL: Trimer 4571|BIOLOGICAL: 3M-052-AF|DRUG: Alum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Single-implant Overdentures Retained by the Novaloc Attachment System
Status: COMPLETED
Conditions: Edentulous Mouth|Edentulous Jaw
Interventions: DEVICE: Novaloc|DEVICE: Locator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dexmedetomidine on Pediatric Heart Operation
Status: COMPLETED
Conditions: Acute Renal Injury
Interventions: DRUG: Dexmedetomidine|DRUG: no dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Role of Low Level Laser Therapy in Acceleration of Teeth Alignment in Lingual Orthodontic Patients
Status: COMPLETED
Conditions: Malocclusion, Angle Class I|Crowding
Interventions: RADIATION: low level laser therapy|DEVICE: Lingual Orthodontics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Explore Potential Plasma and BALF Immunometabolic and Lipidomic Biomarkers for Identifying ARDS Endotypes
Status: UNKNOWN
Conditions: Acute Respiratory Distress Syndrome|Acute Respiratory Failure
Interventions: DIAGNOSTIC_TEST: Integrated Transcriptomics, Metabolomics, and Lipidomics Profiling
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: MOCHI: An RCT of Mindfulness as Treatment for Chronic Pelvic Pain in AD Women
Status: COMPLETED
Conditions: Chronic Pelvic Pain|Depression|Inflammation Pelvic
Interventions: BEHAVIORAL: Mindfulness based stress reduction|BEHAVIORAL: Healthy Lifestyle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Therapeutic Equivalence Study of Ketoconazole Cream 2%
Status: COMPLETED
Conditions: Tinea Pedis
Interventions: DRUG: Experimental: Ketoconazole 2% Cream (Douglas Pharmaceuticals America Ltd.)|DRUG: Active comparator: Ketoconazole 2% Cream (Teva Pharmaceuticals USA)|DRUG: Placebo comparator: Placebo (Douglas Pharmaceuticals America Ltd.)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Injection Platelet-rich Fibrin(I-PRF) in Accelerate Alignment and Leveling
Status: COMPLETED
Conditions: Orthodontic Pathological Resorption of External Root
Interventions: OTHER: injection I-PRF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Inspire Home Study: Utilization of Home Monitoring During Therapy Optimization in Patients With an Inspire Upper Airway Stimulation System (Comparison of Home Sleep Testing vs. In-lab Polysomnography Testing)
Status: COMPLETED
Conditions: Obstructive Sleep Apnea
Interventions: DIAGNOSTIC_TEST: Home Sleep Testing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exploring Relationships Among Balance Performance, Cognitive Dysfunction, Affective Dysregulation, and Community Integration in Veterans With Traumatic Brain Injury (TBI)
Status: UNKNOWN
Conditions: Traumatic Brain Injury|TBI
Interventions: OTHER: Exploring relationships among balance performance, cognitive dysfunction, affective dysregulation, and community integration in Veterans with Traumatic Brain Injury (TBI).
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparing Budesonide Via MAD or INSI Prospective Cohort Study
Status: UNKNOWN
Conditions: Chronic Rhinosinusitis With Nasal Polyps|Allergic Fungal Sinusitis
Interventions: DRUG: Budesonide|DEVICE: Mucosal Atomization Device|DEVICE: NeilMed squeeze bottle for Impregnated Nasal Saline Irrigation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TryCYCLE: A Pilot Study of Early In-bed Leg Cycle Ergometry in Mechanically Ventilated Patients
Status: COMPLETED
Conditions: Intensive Care Unit Acquired Weakness|Critical Care|Mechanical Ventilation|Respiratory Failure
Interventions: DEVICE: In-bed leg cycle ergometry
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Accelerated Theta Burst Stimulation for Treatment of Suicidality in Depressed Patients
Status: RECRUITING
Conditions: Suicide and Depression
Interventions: DEVICE: Transcranial Magnetic Stimulation MagPro R30 with the MCF-B70 figure-of-eight coil (MagVenture, Denmark)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Autogenous Demineralized Dentin Graft Vs Autogenous Bone Graft in Management of Intrabony Defects
Status: RECRUITING
Conditions: Intrabony Periodontal Defect
Interventions: BIOLOGICAL: Autogenous Demineralized Dentin Graft|BIOLOGICAL: Autogenous Bone Graft
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Exercise Induced Hypoalgesia Diabetes
Status: WITHDRAWN
Conditions: Diabetic Peripheral Neuropathy|Diabetic Peripheral Neuropathic Pain
Interventions: OTHER: Moderate Cycling|OTHER: Personalized Tourniquet System
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Pilot Study to Assess the Efficacy of and Tolerance to a QUadruple Therapy to Treat HIV-HCV Coinfected Patients Previously Null Responders
Status: COMPLETED
Conditions: HCV-HIV Co-Infection
Interventions: DRUG: Asunaprevir, Daclatasvir, Ribavirin and Peginterferon alfa-2a
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of AZD2014 in Combination With Selumetinib in Patients With Advanced Cancers
Status: UNKNOWN
Conditions: Triple-Negative Breast Cancer|Squamous Cell Lung Cancer|Non-squamous Cell Lung Cancer With KRAS Mutations|Non-squamous Cell Lung Cancer With Wild-type KRAS
Interventions: DRUG: AZD2014|DRUG: AZD6244
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 12-week Polysomnography Study of Ropinirole Controlled Release for Restless Legs Syndrome
Status: COMPLETED
Conditions: Restless Legs Syndrome (RLS)|Restless Legs Syndrome
Interventions: DRUG: ropinirole CR-RLS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Osteoarthritis by Intra-articular Injection of Bone Marrow Mesenchymal Stem Cells With Platelet Rich Plasma
Status: UNKNOWN
Conditions: Knee Osteoarthritis
Interventions: BIOLOGICAL: 100 million Bone marrow mesenchimal stem cells|BIOLOGICAL: Platelet Rich plasma (PRGF)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Efficacy and Prediction of Deep Brain Stimulation for Treatment-resistant Depression
Status: ACTIVE_NOT_RECRUITING
Conditions: Major Depressive Disorder|Deep Brain Stimulation
Interventions: DEVICE: Deep brain stimulation(Active)|DEVICE: Deep brain stimulation(Sham)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mirtazapine Versus Dexamethasone in Preventing Postoperative Nausea and Vomiting
Status: RECRUITING
Conditions: Post Operative Nausea and Vomiting
Interventions: DRUG: Mirtazapine 30 MG|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: My Best Alaskan Life: A Community-Designed Intervention to Improve Youth/Young Adults' Sexual and Mental Health
Status: NOT_YET_RECRUITING
Conditions: Community-Based Participatory Research|Adolescent Behavior|Mental Depression|Sexual Health
Interventions: BEHAVIORAL: My Best Alaska Life
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Pemetrexed Disodium in the Cerebrospinal Fluid of Patients With Leptomeningeal Metastases
Status: COMPLETED
Conditions: Brain and Central Nervous System Tumors|Chronic Myeloproliferative Disorders|Leukemia|Lymphoma|Lymphoproliferative Disorder|Metastatic Cancer|Multiple Myeloma and Plasma Cell Neoplasm|Myelodysplastic Syndromes|Precancerous Condition|Secondary Myelofibrosis|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: Pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of a Six-Month Regimen of High-Dose Rifampicin, High-Dose Isoniazid, Linezolid, and Pyrazinamide Versus a Standard Nine-Month Regimen for the Treatment of Adults and Adolescents With Tuberculous Meningitis
Status: RECRUITING
Conditions: Tuberculous Meningitis
Interventions: DRUG: Rifampicin (RIF)|DRUG: Isoniazid (INH)|DRUG: Linezolid (LZD)|DRUG: Pyrazinamide (PZA)|DRUG: ethambutol (EMB)|DRUG: Rifampicin|DRUG: Isoniazid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A PILOT STUDY OF DIFFUSION WEIGHTED MRI TO ASSESS ESOPHAGEAL TUMOR RESONSE TO NEOADJUVANT CHEMORADIATION
Status: COMPLETED
Conditions: Esophageal Cancer
Interventions: RADIATION: Chemotherapy|RADIATION: Radiation Therapy|PROCEDURE: Surgery|DEVICE: MRI Imaging|OTHER: Blood Draws
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p