pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Psychological Well-being of Patients Awaiting for Cardiac Surgery During the COVID-19 Pandemic
Status: UNKNOWN
Conditions: Anxiety and Fear|Anxiety Depression|Anxiety Postoperative|Psychological Stress
Interventions: BEHAVIORAL: HADS|BEHAVIORAL: a survey
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of a New Catheter Material for Intermittent Catheterization
Status: COMPLETED
Conditions: Catheterization (Clean, Intermittent Urinary Catheterization)
Interventions: DEVICE: LoFric POBE 2.0|DEVICE: LoFric PVC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Continuous Intravenous Versus Usual Subcutaneous Insulin in Acute Ischemic Stroke
Status: COMPLETED
Conditions: Acute Stroke|Acute Cerebral Ischemia
Interventions: DRUG: Insulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Physical Exercises Program on Social Functioning, Alexithymia and Sense of Coherence Among Patients With Bipolar Disorders
Status: COMPLETED
Conditions: Social Functioning, Alexithymia and Sense of Coherence , Bipolar Disorders
Interventions: BEHAVIORAL: Physical exercises program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Stress Ball Use in Patients Undergoing Coronary Angiography
Status: COMPLETED
Conditions: Pain
Interventions: DEVICE: The Effect of Stress Ball Use on Immobilization Comfort, Pain Level and Vital Signs in Patients Undergoing Coronary Angiography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of Laser Treatment of Melasma
Status: COMPLETED
Conditions: Refractory Mixed Type Melasma
Interventions: DEVICE: Q-Switched Nd:YAG Laser (RevLite)|DRUG: Retin-A and microdermabrasion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Maintaining Visual Performance in Participants Who Engage in Electronic Visual Tasking While Using Restasis®
Status: COMPLETED
Conditions: Dry Eye Syndromes
Interventions: DRUG: Cyclosporine 0.05% Ophthalmic Emulsion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: e-Cigarettes Versus NRT Gum for Smoking Cessation
Status: TERMINATED
Conditions: Nicotine Addiction|Smoking Cessation
Interventions: DRUG: Nicotine polacrilex|OTHER: STAM 1100mAh CE4 eGo Clearomizer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study to Evaluate the Effect of Injection Lypolysis (Lipodissolve) Treatments to Reduce Body Fat
Status: COMPLETED
Conditions: Abdominal Subcutaneous Fat
Interventions: DRUG: phosphatidylcholine and deoxycholate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Metronomic Chemotherapy With Tegafur/Uracil for Head and Neck Squamous Cell Carcinoma
Status: UNKNOWN
Conditions: Head and Neck Cancer
Interventions: DRUG: tegafur-uracil
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transanal Irrigation - Best Treatment Possibility for Low Anterior Resection Syndrome? Multicenter, Randomized Clinical Trial
Status: RECRUITING
Conditions: Low Anterior Resection Syndrome
Interventions: PROCEDURE: Transanal irrigation|COMBINATION_PRODUCT: Best supportive care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Immunogenicity and Safety of Meningococcal Vaccine GSK134612 Given as 1 or 2 Doses to Healthy 9-12 Months Old Toddlers.
Status: COMPLETED
Conditions: Infections, Meningococcal
Interventions: BIOLOGICAL: Meningococcal vaccine GSK134612
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Absorption, Metabolism and Excretion of Apigenin and Apigenin Glycosides
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: Chamomile Tea|OTHER: Parsley based drink|OTHER: Parsley Yogurt|OTHER: Apigenin|OTHER: Parsley-based drink (II)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Engaging Patients to Help Achieve Increased Patient Choice and Engagement for AFib Stroke Prevention
Status: COMPLETED
Conditions: Atrial Fibrillation|Atrial Flutter|Stroke|Cardiac|Heart Failure|Arrhythmia
Interventions: BEHAVIORAL: SDMT|BEHAVIORAL: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Exploration of Theory of Mind in a Situation of Social Rejection in Borderline Personality Disorder
Status: TERMINATED
Conditions: Borderline Personality Disorder|Social Rejection|Social Skills|Cognitive Function 1, Social
Interventions: BEHAVIORAL: Cyberball
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Exploring the Outcomes of System Supports for Youth With Mental Illness and/or Addictions and Their Families
Status: COMPLETED
Conditions: Mental Health Disorder|Addiction
Interventions: OTHER: Navigation|OTHER: Resource List
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study to Investigate the Safety and Efficacy of Sofosbuvir/Velpatasvir in Adolescents and Children With Chronic HCV Infection
Status: COMPLETED
Conditions: Hepatitis C Virus Infection
Interventions: DRUG: SOF/VEL|DRUG: SOF/VEL
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Glistenings in Intraocular Lenses Implanted in Normal Patients Following Routine Cataract Extraction.
Status: WITHDRAWN
Conditions: Glistenings
Interventions: DEVICE: Intraocular lens
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: Effect of PECS II, Parasternal and Serratus Plane Blocks on Postoperative Pain in MIDCAB Surgery
Status: NOT_YET_RECRUITING
Conditions: Pain, Postoperative|Coronary Artery Disease
Interventions: PROCEDURE: pectoral nerve block (PECS II), parasternal and serratus plane blocks|OTHER: analgesic
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Determining Swallow Outcomes in Head & Neck Lymphedema Subjects Receiving Early Intervention With Pneumatic Compression
Status: TERMINATED
Conditions: Head and Neck Lymphedema
Interventions: DEVICE: FT-CC and Swallow Exercises|OTHER: Swallow Exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigation of Neurophysiological Markers, Possibly Specific of Two Subforms of Psychotic Disorders
Status: RECRUITING
Conditions: Schizophrenia
Interventions: OTHER: compare the two groups of schizophrenic patients|OTHER: compare the two groups of schizophrenic patients versus volunteers
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Topical Tacrolimus in Different Subtypes With Cutaneous Lupus Erythematosus (CLE)
Status: COMPLETED
Conditions: Cutaneous Lupus Erythematosus
Interventions: DRUG: Tacrolimus ointment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Hairy Cell Leukaemia Variant and Relapsing Hairy Cell Leukaemia With Cladribine Plus Rituximab
Status: COMPLETED
Conditions: Hairy Cell Leukemia (HCL)
Interventions: DRUG: 2CdA +/- Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Interferential Current Therapy After Total Knee Arthroplasty
Status: COMPLETED
Conditions: Total Knee Arthroplasty
Interventions: DEVICE: Interferential Current|DEVICE: Sham Interferential Current
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Oxygen Delivery Methods of Nasal Catheter on the Incidence of Hypoxemia in Patients With Painless Gastroscopy
Status: RECRUITING
Conditions: Hypoxemia
Interventions: OTHER: Oxygen delivery mode
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: REVIVE(Randomized Exploratory Clinical Trial to Evaluate the Safety and Effectiveness of Stem Cell Product in Alcoholic Liver Cirrhosis Patient)
Status: COMPLETED
Conditions: Alcoholic Liver Cirrhosis
Interventions: BIOLOGICAL: Livercellgram
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Cognitive Behavioral Couples Therapy for Post-traumatic Stress Disorder
Status: COMPLETED
Conditions: Post-traumatic Stress Disorder
Interventions: BEHAVIORAL: Cognitive behavioral couples therapy for post-traumatic stress disorder (CBCT for PTSD)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Foot Mechanical Stimulation for Treatment of Gait and Gait Related Disorders in Parkinson's Disease and Progressive Supranuclear Palsy.
Status: TERMINATED
Conditions: Idiopathic Parkinson's Disease|Progressive Supranuclear Palsy
Interventions: DEVICE: Foot Mechanical Stimulation (GONDOLA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Short-Term Endogenous Hydrogen Sulfide Upregulation For Vein Graft Disease
Status: NOT_YET_RECRUITING
Conditions: Vascular Diseases|Surgery
Interventions: DIETARY_SUPPLEMENT: Scandi-Shake
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Intraductal Secretin Stimulation Test: What Is the Proper Collection Time?
Status: COMPLETED
Conditions: Cholangiopancreatography, Endoscopic Retrograde
Interventions: PROCEDURE: Intraductal secretin test (IDST)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Low-Dose Cytarabine in Treating Infants With Down Syndrome and Transient Myeloproliferative Disorder
Status: WITHDRAWN
Conditions: Leukemia
Interventions: DRUG: cytarabine|PROCEDURE: observation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Therapeutic Monitoring of Mycophenolate Mofetil (MMF/CellCept) After Kidney Transplantation
Status: COMPLETED
Conditions: Kidney Transplantation
Interventions: DRUG: Mycophenolate mofetil|DRUG: Cyclosporine|DRUG: Tacrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Anti-Cancer Therapies Targeting the MAPK Pathway in Patients With Advanced NSCLC
Status: COMPLETED
Conditions: Advanced Non-squamous Non-small-cell Lung Cancer
Interventions: DRUG: ERAS-007|DRUG: ERAS-601|DRUG: Osimertinib|DRUG: Sotorasib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: C.A.P.A.B.L.E. (Cross-Training and Physical Activity: A Better Life Experience Study)
Status: RECRUITING
Conditions: Cancer Survivors
Interventions: BEHAVIORAL: 12 week pilot intervention study.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Empower Neuromodulation System - Pilot Study for Anxiety Treatment
Status: TERMINATED
Conditions: Generalized Anxiety Disorder
Interventions: DEVICE: Empower Neuromodulation System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Ultrasound-Guided PRP Versus Corticosteroid Injection in Patients With Ulnar Neuropathy at Elbow
Status: COMPLETED
Conditions: Ulnar Neuropathy at Elbow
Interventions: DRUG: Triamcinolone Acetonide 40mg/mL|DRUG: PRP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Postmarket Clinical Follow-Up Study on Arcadius XP L® Interbody Fusion Device
Status: ENROLLING_BY_INVITATION
Conditions: Chronic Low-back Pain|Degenerative Disc Disease|Spondylolysis Lumbar|Postdiscectomy Syndrome|Posttraumatic Instability
Interventions: DEVICE: ArcadiusXP L® Interbody Fusion System
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Mechanisms and Outcome-Prognostication for Paresthesia-based and -Free Spinal Cord Stimulation
Status: RECRUITING
Conditions: Neuropathic Pain|Chronic Pain
Interventions: DEVICE: Spinal Cord Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of High and Low Roasted Coffee on Vascular Response
Status: COMPLETED
Conditions: Cardiovascular Disease
Interventions: DIETARY_SUPPLEMENT: Low roast coffee|DIETARY_SUPPLEMENT: High roast coffee|DIETARY_SUPPLEMENT: Control (Caffeine dissolved in water)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: RO4929097 and Erlotinib Hydrochloride in Treating Patients With Stage IV or Recurrent Non-small Cell Lung Cancer
Status: TERMINATED
Conditions: Recurrent Non-Small Cell Lung Carcinoma|Stage IV Non-Small Cell Lung Cancer
Interventions: DRUG: Erlotinib Hydrochloride|DRUG: Gamma-Secretase Inhibitor RO4929097|OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacological Study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HeartCare Immuno-optimization in Cardiac Allografts (MOSAIC)
Status: NOT_YET_RECRUITING
Conditions: Heart Transplant|Immunosuppression|Allograft
Interventions: DIAGNOSTIC_TEST: HeartCare
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioavailability Study Comparing Tolvaptan Administered Via Nasogastric Tube to Tolvaptan Tablets Swallowed Intact
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Tolvaptan|DRUG: Tolvaptan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Glucose-insulin-potassium Therapy Improves Lactic Acidosis in Liver Transplantation
Status: COMPLETED
Conditions: Liver Transplantation
Interventions: OTHER: saline|OTHER: Insulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fasting Study of Metolazone Tablets 5 mg and Zaroloxyn® Tablets 5 mg
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Metolazone Tablets 5 mg|DRUG: Zaroloxyn® Tablets 5 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Spinal Cord Stimulation for Restless Legs Syndrome
Status: COMPLETED
Conditions: Restless Legs Syndrome|Neuropathic Pain
Interventions: DIAGNOSTIC_TEST: Dual-energy X-ray absorptiometry Scan|OTHER: Laboratory Measurements|OTHER: Blood Flow Measurement|OTHER: Continuous Blood Pressure|OTHER: Partial pressure of oxygen|OTHER: Microneurography|OTHER: Anthropometric Measurements|BEHAVIORAL: John Hopkins Restless Legs Severity Scale|BEHAVIORAL: Continuous Blood Pressure Diary
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Prospective Randomized Study Comparing Different Dilation Durations for Endoscopic Papillary Balloon Dilatation
Status: UNKNOWN
Conditions: Choledocholithiasis
Interventions: PROCEDURE: Endoscopic papillary balloon dilation-5 minutes|PROCEDURE: Endoscopic papillary balloon dilation-1 minute
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: The Difference of Angle of Femoral Component Rotation in TKA With Gap Balance and Measured Resection Technique
Status: UNKNOWN
Conditions: Osteoarthritis, Knee
Interventions: PROCEDURE: the gap balance type of total knee arthroplasty|PROCEDURE: the measured resection type of total knee arthroplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Sex Hormones and Orthostatic Tolerance
Status: COMPLETED
Conditions: Orthostatic Intolerance
Interventions: DRUG: Ganirelix acetate|DRUG: 17β-Oestradiol|DRUG: Progesterone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Extension of AOC 1001-CS1 (MARINA) Study in Adult Myotonic Dystrophy Type 1 (DM1) Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: DM1|Muscular Dystrophies|Myotonic Dystrophy|Myotonic Dystrophy 1|Myotonic Disorders|Muscular Disorders, Atrophic|Muscular Diseases|Musculoskeletal Diseases|Neuromuscular Diseases|Nervous System Diseases|Genetic Diseases, Inborn|Heredodegenerative Disorders, Nervous System|Neurodegenerative Diseases
Interventions: DRUG: Placebo|DRUG: AOC 1001
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: geRman-widE mulTicenter Analysis of oRal Anticoagulation-associated intraCerebral hEmorrhage
Status: COMPLETED
Conditions: OAC-ICH|Acute Management of OAC-ICH|Resumption of OAC
Interventions: OTHER: no intervention, only descriptive data analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study Comparing Two Doses of MG01CI and Placebo in Adults With Predominantly Inattentive Attention Deficit Hyperactivity Disorder
Status: COMPLETED
Conditions: ADHD Predominantly Inattentive Type
Interventions: DRUG: Metadoxine (MG01CI)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Adjuvant Study of Pyrotinib in Combination With Trastuzumab in HER2 Positive Invasive Breast Cancer
Status: NOT_YET_RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Pyrotinib|DRUG: Trastuzumab|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The PhOCus Trial: Implementation of Pharmacogenomic Testing in Oncology Care
Status: RECRUITING
Conditions: Gastrointestinal Cancer|Head and Neck Cancer|Dihydropyrimidine Dehydrogenase Deficiency|UGT1A1 Gene Mutation|Breast Cancer
Interventions: OTHER: Availability of clinical decision support based on pharmacogenomic results.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Milnacipran for Lumbosacral Radicular Pain
Status: COMPLETED
Conditions: Radicular Pain Related to Lumbosacral Disc Disease
Interventions: DRUG: Milnacipran|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Effect of a Vegetal Oil on Cognitive Impairment
Status: UNKNOWN
Conditions: Cognitive Impairments|Alzheimer Disease
Interventions: DIETARY_SUPPLEMENT: Lipidic Blend 1|DIETARY_SUPPLEMENT: Lipidic Blend 2|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Individualized Neuroimaging Biomarkers for Predicting rTMS Response in OCD
Status: RECRUITING
Conditions: Obsessive-Compulsive Disorder
Interventions: DEVICE: Repetitive Transcranial Magnetic Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study To Evaluate The Abuse Potential Of Single Oral Doses Of Dimebon (Latrepirdine) In Healthy Recreational Polydrug Users
Status: COMPLETED
Conditions: Alzheimer's Disease|Huntington's Disease
Interventions: DRUG: dimebon|DRUG: dimebon|DRUG: dimebon|DRUG: placebo|DRUG: alprazolam|DRUG: alprazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Pilot Study to Evaluate the Effects of a Vaccine (HSPPC-96) Combined With Ipilimumab in Patients With Advanced Melanoma
Status: WITHDRAWN
Conditions: Melanoma
Interventions: DRUG: ipilimumab|DRUG: HSPPC-96
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Using Smartphones to Provide Recovery Support Services
Status: COMPLETED
Conditions: Substance Use Disorder (SUD)|Recovery
Interventions: OTHER: EMA Only|OTHER: EMI Only|OTHER: EMA+EMI|OTHER: Neither - RSAU
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Long-term Comparative Analysis of Visual Outcomes With 3 Intraocular Lenses: Monofocal, Trifocal and Accommodating
Status: UNKNOWN
Conditions: Intraocular Lens
Interventions: DEVICE: Trifocal lens AT LISA TRI, Zeiss|DEVICE: Accommodating Tetraflex HD lens, Lenstec inc.|DEVICE: Monofocal lens, Softec HD
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Video Call Assisted Assessment of Acute Stroke
Status: RECRUITING
Conditions: Stroke|Cerebrovascular Disorders|Brain Diseases|Nervous System Diseases|Vascular Diseases|Central Nervous System Diseases
Interventions: DIAGNOSTIC_TEST: Video call assisted assessment of acute stroke
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Yale-Harvard Hotel-based Closed-Loop Studies in Children (HY-GRAID)
Status: COMPLETED
Conditions: Type1 Diabetes
Interventions: DEVICE: Zone-Model Predictive Control Artificial Pancreas (ZMPC_AP)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Therapeutic Effect of Scalp Acupuncture Treatment for Motor Dysfunction in Children With Cerebral Palsy
Status: COMPLETED
Conditions: Cerebral Palsy|Motor Dysfunction|Acupuncture
Interventions: OTHER: scalp acupuncture treatment|OTHER: Rehabilitation Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acute Normovolemic Hemodilution in High Risk Cardiac Surgery Patients.
Status: RECRUITING
Conditions: C.Surgical Procedure; Cardiac
Interventions: PROCEDURE: Acute normovolemic hemodilution|PROCEDURE: Standard care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Safety and Clinical Outcome of Using FR-Mask in Breast Cancer Patients With Radiation-irritated Skin After Radiotherapy
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: OTHER: FR-Mask
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Anti-suicidal Effects of Buprenorphine In Depressed Individuals
Status: WITHDRAWN
Conditions: Suicidal Ideation|Major Depressive Disorder
Interventions: DRUG: Belbuca Buccal Product|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bridging Allogeneic Hematopoietic Stem Cell Transplantation or Not After CD19 CAR - T (S1904) Cell Therapy for r/r B-cell Acute Lymphoblastic Leukemia, a Prospective, Open, Multicenter, Randomized, Control Study
Status: NOT_YET_RECRUITING
Conditions: Relapsed Adult ALL|B-cell Acute Lymphoblastic Leukemia|Refractory Acute Lymphoblastic Leukemia|Relapsed Pediatric ALL
Interventions: BIOLOGICAL: Senl_B19 autologous CAR-T (S1904) treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety and Tolerability Study of CTP-730 in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: CTP-730|DRUG: Placebo for CTP-730
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety and Efficacy of K-134 for the Treatment of Intermittent Claudication
Status: COMPLETED
Conditions: Intermittent Claudication
Interventions: DRUG: K-134|DRUG: Cilostazol 100 mg BID|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Clinical Study to Describe Biological Safety and Pharmacokinetics of Tyrphostin
Status: UNKNOWN
Conditions: Healthy
Interventions: COMBINATION_PRODUCT: Tirfostina/L-Carnitina
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Laser Therapy Following Radiotherapy for Gynecological Cancer
Status: UNKNOWN
Conditions: Pelvic Radiotherapy|Gynecological Cancer|Dyspareunia|Vaginal Dryness
Interventions: DEVICE: Microablative Fractional CO2 Laser Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Cognitive Deficits in Multiple Sclerosis With High-Definition Transcranial Direct Current Stimulation
Status: RECRUITING
Conditions: Multiple Sclerosis, Relapsing-Remitting
Interventions: DEVICE: Transcranial Direct Current Stimulation|DEVICE: Sham transcranial direct current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study to Assess the Accuracy of Blood Pressure Assessment by the Omron HeartGuide Smartwatch
Status: COMPLETED
Conditions: Hypertension|Cardiac Disease|Surgery
Interventions: OTHER: Omron Wearable Device|OTHER: Standard Arterial Line
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Doppler-guided Haemorrhoidal Artery Ligation With Suture Mucopexy vs. Suture Mucopexy Alone
Status: COMPLETED
Conditions: Third Degree Hemorrhoids
Interventions: DEVICE: mucopexy +/- Doppler-guided haemorrhoidal artery ligation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Diquafosol Prophylactic Therapy to Prevent Dry Eye Disease for Cataract Surgery Patients in Indonesia
Status: RECRUITING
Conditions: Dry Eye Disease
Interventions: DRUG: Diquafosol sodium 3%|DRUG: Sodium hyaluronate 0.1%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Tongue Muscular Assessment in Children (TMAC) - Reproducibility Testing
Status: NOT_YET_RECRUITING
Conditions: Healthy
Interventions: OTHER: Sleep quality assessment|OTHER: Anthropometry|OTHER: Tongue strength assessment|OTHER: Tongue endurance assessment|OTHER: Orofacial praxis assessment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Digital Self-efficacy Training to Bridge Waiting Times for Psychotherapy
Status: RECRUITING
Conditions: Psychiatric Disorder|Waiting for Psychotherapy
Interventions: BEHAVIORAL: Digital self-efficacy training|BEHAVIORAL: Ecological Momentary Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Clinical Evaluation of the Performance of a Newly Developed Glass Ionomer Restorative for Posterior Restorations in an Adult Population
Status: TERMINATED
Conditions: Tooth Wear|Glass Ionomer Cements
Interventions: DEVICE: Ketac Universal Aplicap Glass Ionomer Restorative (3M) (test group)|DEVICE: Ketac Molar Quick Aplicap Glass Ionomer Restorative (control group)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Cognitive Training in Older and Younger Adults
Status: NOT_YET_RECRUITING
Conditions: Cognitive Change
Interventions: BEHAVIORAL: Visual and / or Auditory Cognitive Tasks (1)|BEHAVIORAL: Visual and / or Auditory Cognitive Tasks (2)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Jianpi Huatan Decoction on Advanced Colorectal Cancer
Status: UNKNOWN
Conditions: Colorectal Neoplasms
Interventions: DRUG: Jianpi Huatan dispensing granule|DRUG: Placebo granule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Emotional Regulation in Patients With Implanted Automatic Defibrillator
Status: COMPLETED
Conditions: Cardiac Arrhythmia|Ventricular Fibrillation|Ventricular Tachycardia
Interventions: BEHAVIORAL: Mindfulness-based stress reduction program|BEHAVIORAL: App REM volver a casa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Thalomid and Carboplatin for the Treatment of Pediatric Brain Stem Glioma
Status: COMPLETED
Conditions: Brain Stem Neoplasms, Primary|Neoplasms, Brain Stem
Interventions: DRUG: Carboplatin|DRUG: Thalomid|PROCEDURE: External Beam Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chronic Effects of Fats on Satiety & Energy Needs
Status: TERMINATED
Conditions: Overweight|Obesity
Interventions: OTHER: SFA|OTHER: MUFA|OTHER: PUFA|OTHER: LCn3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Cognitive-Behavioral Therapy for Children With Nightmares
Status: RECRUITING
Conditions: Nightmare|Suicidal Ideation|Children, Only
Interventions: BEHAVIORAL: Cognitive Behavioral Therapy for Nightmares in Children
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamics of JNJ-42756493 in Adult Participants With Advanced or Refractory Solid Tumors or Lymphoma
Status: COMPLETED
Conditions: Tumor or Lymphoma
Interventions: DRUG: JNJ-42756493: Part 1|DRUG: JNJ-42756493: Part 2|DRUG: JNJ-42756493: Part 3|DRUG: JNJ-42756493: Part 4
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Beta-alanine and Elder Endurance
Status: COMPLETED
Conditions: Physical Endurance
Interventions: DIETARY_SUPPLEMENT: Beta-alanine|DIETARY_SUPPLEMENT: Placebo|BEHAVIORAL: Muscular endurance exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of PD5K3 in Healthy Adult Volunteers
Status: COMPLETED
Conditions: Lymphoblastic Leukemia, Acute|Lymphoblastic Lymphoma
Interventions: DRUG: PD5K3|DRUG: Placebo|DRUG: Pegaspargase
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of a Novel Nutraceutical on Weight Loss and Weight Maintenance in Obese Subjects
Status: COMPLETED
Conditions: Obesity
Interventions: DIETARY_SUPPLEMENT: THIAA|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Combine Effects of Brunnstorm Movement Therapy and LLLT in Chronic Stroke Patient
Status: COMPLETED
Conditions: Chronic Stroke
Interventions: OTHER: Brunnstorm movement therapy|OTHER: Combined Brunnstorm Movement therapy and low level laser therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Is MS14 Helpful in Schizophrenia?
Status: UNKNOWN
Conditions: Schizophrenia
Interventions: DRUG: MS14|DRUG: Risperidone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Carmustine Plus O6-benzylguanine in Treating Patients With Recurrent or Progressive Glioma
Status: COMPLETED
Conditions: Brain and Central Nervous System Tumors
Interventions: DRUG: O6-benzylguanine|DRUG: carmustine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Effects of SH T00658ID on Libido
Status: COMPLETED
Conditions: Contraception|Libido
Interventions: DRUG: EV/DNG (Qlaira, BAY86-5027, SH T00658ID)|DRUG: Microgynon|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Poplar Propolis on Metabolic Disturbances of Insulin Resistance
Status: COMPLETED
Conditions: Insulin Resistance
Interventions: DIETARY_SUPPLEMENT: Propolis|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Artemether/Lumefantrine and Nevirapine Interaction Study in HIV-infected Adults
Status: COMPLETED
Conditions: Malaria|HIV
Interventions: DRUG: Artemether/Lumefantrine|DRUG: Artemether/ lumefantrine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combined Resistance and Aerobic Exercise is Better Than Resistance Training Alone to Improve Functional Performance of Hemodialysis Patients - Results of a Randomized Trial
Status: COMPLETED
Conditions: End Stage Renal Disease
Interventions: BEHAVIORAL: exercise training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: CIRcadian Rhythms and CortisoL. Effects on Substrate Metabolism and Clock Gene Expression and Functioning
Status: RECRUITING
Conditions: Healthy
Interventions: DRUG: Prednisolone|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of Psilocybin-assisted Psychotherapy (PaP) for the Treatment of Post-traumatic Stress Disorder (PTSD) in Military Veterans
Status: NOT_YET_RECRUITING
Conditions: PTSD
Interventions: DRUG: Psilocybin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Bioavailability of Risankizumab in Pre-filled Syringe or Auto-injector in Healthy Adult Participants
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Risankizumab|DRUG: Risankizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Phenotypic and Genetic Assessment of Tracheal and Esophageal Birth Defects in Patients
Status: RECRUITING
Conditions: Tracheoesophageal Fistula|Esophageal Atresia|Laryngeal Cleft|Tracheal Stenosis|Bronchial Stenosis|Esophageal Bronchus|Congenital High Airway Obstruction Syndrome
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical Study to Evaluate the Efficacy of Anakinra in Patients With Rheumatoid Arthritis and Diabetes
Status: TERMINATED
Conditions: Diabetes Mellitus, Type 2|Arthritis, Rheumatoid
Interventions: DRUG: Anakinra|DRUG: TNF alpha inhibitors
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Breathox Device Inhalation Therapy in the Treatment of Acute Symptoms Associated With COVID-19 and in the Prevention of the Use of Health Resources
Status: COMPLETED
Conditions: COVID-19
Interventions: DRUG: Dispersible NaCl powder 10 sessions|DRUG: Dispersible NaCl powder 5 sessions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: DTaP and Apnea/Bradycardia in Preterm Infants
Status: COMPLETED
Conditions: Prolonged Apnea|Prolonged Bradycardia
Interventions: BIOLOGICAL: Infanrix|BIOLOGICAL: Pediatrix
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: PREVENTION
Clinical trial: Suprascapular Neuropathy in the Setting of Rotator Cuff Tears: Results of Arthroscopic Treatment
Status: COMPLETED
Conditions: Entrapment Neuropathy|Rotator Cuff Tear
Interventions: PROCEDURE: Dissection of the superior transverse scapular ligament
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mechanisms of Increased Androgen Production Among Women With Polycystic Ovary Syndrome
Status: COMPLETED
Conditions: Polycystic Ovary Syndrome
Interventions: RADIATION: 3-D Ultrasound|DRUG: recombinant human chorionic gonadotropin|DRUG: Recombinant human follicle stimulating hormone|DRUG: Adrenocorticotropin|DRUG: Dexamethasone|DRUG: Glucose
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Definitive Selection of Neuroimaging Biomarkers for the Diagnosis and Treatment to Common Mental Disorders
Status: COMPLETED
Conditions: Common Mental Disorder
Interventions: DRUG: Antipsychotic drugs|DRUG: Mood stabilizer|DRUG: Paroxetine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Glycine in Cystic Fibrosis
Status: TERMINATED
Conditions: Cystic Fibrosis
Interventions: DIETARY_SUPPLEMENT: Glycine|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Adjuvant Gemcitabine Plus Oxaliplatin Versus Gemcitabine Plus Cisplatin for Completely Resected Stage IB/II/IIIA NSCLC
Status: UNKNOWN
Conditions: Lung Cancer
Interventions: DRUG: gemcitabine|DRUG: Oxaliplatin|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Assessment of an in-Patient Glucose Monitoring System (Accu-Chek Inform Cobas IT 1000)
Status: COMPLETED
Conditions: Diabetes Mellitus|Blood Glucose|Hospital Information Systems|Medical Device
Interventions: DEVICE: Accu Chek Inform and Cobas IT 1000
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: To Assess the Effect of AZD1722 on the Pharmacokinetics of Cefadroxil in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Treatment A (cefadroxil alone)|DRUG: Treatment B - AZD1722 followed by cefadroxil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of AC2993 Compared With Insulin Glargine in Patients With Type 2 Diabetes Also Using Combination Therapy With Sulfonylurea and Metformin
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Exenatide (AC2993)|DRUG: Insulin glargine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: URMC Related Haplo-identical Donor BMT
Status: COMPLETED
Conditions: Hematological Disease|Immune Deficiencies|Solid Tumors|Myelofibrosis|Multiple Myeloma|Lymphoma
Interventions: RADIATION: Total Body Irradiation 1200 cGy|DRUG: Fludarabine|DRUG: Pre-Stem Cell Infusion Cyclophosphamide|DRUG: Pre-Stem Cell Infusion Mesna|DRUG: Busulfan|DRUG: Melphalan|PROCEDURE: Stem Cell Infusion|DRUG: Post-Stem Cell Infusion Cyclophosphamide|DRUG: Post-Stem Cell Infusion Mesna|DRUG: Thiotepa
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Glucagon Response to Prandial Insulin Administration in Persons With Type 1 Diabetes
Status: TERMINATED
Conditions: Type 1 Diabetes|Hyperglycemia, Postprandial
Interventions: DRUG: Insulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Evaluate the Safety, Tolerability, Pharmacokinetics (PK), and Pharmacodynamics (PD) of TAK-988 in Healthy Participants
Status: WITHDRAWN
Conditions: Healthy Volunteers
Interventions: DRUG: TAK-988|DRUG: TAK-988 Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: HA35 Moderate Alcoholic Hepatitis (AH) Study
Status: RECRUITING
Conditions: Alcoholic Hepatitis
Interventions: DRUG: Sodium Hyaluronate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Supervised Group Based Exercise for Men With Prostate Cancer on Androgen Deprivation Therapy
Status: COMPLETED
Conditions: Prostatic Neoplasms|Exercise Therapy|Androgen Deprivation Therapy
Interventions: BEHAVIORAL: Group based exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Palbociclib in Treating Patients With Metastatic HER-2 Positive Breast Cancer With Brain Metastasis
Status: TERMINATED
Conditions: Breast Carcinoma Metastatic in the Brain|Estrogen Receptor Negative|HER2/Neu Negative|HER2/Neu Positive|Progesterone Receptor Negative|Recurrent Breast Carcinoma|Stage IV Breast Cancer
Interventions: PROCEDURE: Cognitive Assessment|DRUG: Palbociclib|PROCEDURE: Quality-of-Life Assessment|BIOLOGICAL: Trastuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Bolus Surfactant Replacement Therapy Versus Standard Care in Term Neonates With Meconium Aspiration Syndrome
Status: COMPLETED
Conditions: Meconium Aspiration Syndrome|Surfactant Dysfunction
Interventions: DRUG: Bovine surfactant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Single-dose Study to Investigate the Effects of 3 Different Doses of Inhaled AZD2115 in COPD Patients
Status: COMPLETED
Conditions: COPD
Interventions: DRUG: AZD2115|DRUG: Placebo|DRUG: Indacaterol|DRUG: Indacaterol + Tiotropium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Effect of AMG 510 on the Pharmacokinetics (PK) of Digoxin in Healthy Participants
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DRUG: AMG 510|DRUG: Digoxin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study With IMC-A12 (Cixutumumab) in Patients Who Have Not Previously Been Treated With Chemotherapy With Metastatic Prostate Cancer
Status: COMPLETED
Conditions: Adenocarcinoma of the Prostate
Interventions: DRUG: IMC-A12 (Cixutumumab)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT