pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Endobiliary Percutaneous Cryobiopsy in Malignant Biliary Obstruction
Status: RECRUITING
Conditions: Biliary Tract Carcinoma|Biliary Obstruction
Interventions: DEVICE: Cryobiopsy catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Stress and Fertility: How to Lower Stress When Trying to Conceive
Status: UNKNOWN
Conditions: Anxiety|Infertility, Female
Interventions: BEHAVIORAL: In-person yoga for fertility group|BEHAVIORAL: Online yoga for fertility group|BEHAVIORAL: In person discussion only group
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Robot Assisted Gait Training In Children With Cerebral Palsy
Status: COMPLETED
Conditions: Cerebral Palsy|Physical Therapy|Robotic Rehabilitation|Motor Skills Disorders
Interventions: DEVICE: Robot assisted gait training|OTHER: Conventional physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Healthier You: Optimizing Screening, Brief Interventions, and Referral to Treatment (SBIRT) in the Emergency Department
Status: COMPLETED
Conditions: Drug Abuse
Interventions: BEHAVIORAL: Computer-delivered Brief Intervention (CBI)|BEHAVIORAL: Intervener-delivered Brief Intervention (IBI)|BEHAVIORAL: Adapted Motivational Enhancement Therapy (AMET)|BEHAVIORAL: Enhanced Usual Care (EUC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: COPILOT-HF: Cooperative Program for ImpLementation of Optimal Therapy in Heart Failure
Status: RECRUITING
Conditions: Heart Failure
Interventions: DRUG: SGLT2i, beta blocker, ARNI, MRA, MTD|BEHAVIORAL: Education-First
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Cognitive Exercise Therapy Approach and Yoga in Adolescents With Dysmenorrhoea
Status: NOT_YET_RECRUITING
Conditions: Dysmenorrhea|Primary Dysmenorrhea
Interventions: OTHER: Cognitive Exercise Therapy Approach|OTHER: Yoga|OTHER: Routine Medical Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Phase I Study of PSD502 (Lidocaine Prilocaine Spray) Applied to the Glans Penis up to Three Times a Day for 21 Days in Healthy Male Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: PSD502
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: The Distraction of Knee Joint to Alleviate osteoArthritic Pain (DiKAP) Trial
Status: UNKNOWN
Conditions: Knee Osteoarthritis
Interventions: OTHER: Standard Physcial Therapy|OTHER: Intermittent Mechanical Traction|OTHER: Continuous Mechanical Traction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Performed at Various Medical Centers to Learn More About Survival and Expected Course of Pulmonary Arterial Hypertension, a Type of High Blood Pressure in the Lungs Related to the Narrowing of the Small Blood Vessels in the Lungs
Status: COMPLETED
Conditions: Pulmonary Arterial Hypertension
Interventions: DRUG: PAH medication
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Trial to Evaluate the Efficacy and Safety of TP-03, LIBRA Study
Status: COMPLETED
Conditions: Blepharitis
Interventions: DRUG: Lotilaner|DRUG: Vehicle Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mental Health in Veterans and Families After Group Therapies
Status: RECRUITING
Conditions: Post-Traumatic Stress Disorders
Interventions: BEHAVIORAL: CBT (Cognitive Behavior Therapy)|BEHAVIORAL: EFT (Emotional Freedom Techniques)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Comparison of Transdermal Fentanyl and Morphine for Oral Mucositis Pain in Nasopharyngeal Cancer Patients
Status: UNKNOWN
Conditions: Pain|Nasopharyngeal Carcinoma|Head and Neck Cancer|Radiation Induced Oral Mucositis
Interventions: DRUG: Fentanyl|DRUG: Morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Elders Preferences in Care Decisions
Status: COMPLETED
Conditions: Early Detection of Cancer|Colon Cancer|Decision Making|Patient-Centered Care
Interventions: BEHAVIORAL: Making A Decision About CRC Screening|BEHAVIORAL: Drivers 65 Plus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Outcomes to the Nutritional Need of Patients With Parkinson's Disease
Status: UNKNOWN
Conditions: Deglutition Disorders|Parkinson Disease|Nursing|Quality of Life
Interventions: DIETARY_SUPPLEMENT: weancare-domus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Impact of Yogurt on Gastrointestinal Health, Regularity, and Thoughts
Status: COMPLETED
Conditions: Gastrointestinal Dysfunction|Physiological Stress|Cognition - Other
Interventions: DIETARY_SUPPLEMENT: Yogurt with B. lactis and added cane sugar
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: ACT-128800 in Patients With Moderate to Severe Chronic Plaque Psoriasis
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: ACT-128800|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dimiracetam in Painful Neuropathies Affecting AIDS Patients
Status: UNKNOWN
Conditions: Acquired Immunodeficiency Syndrome
Interventions: DRUG: Dimiracetam|DRUG: Dimiracetam 25 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Placebo-controlled Study of Levetiracetam In Children (1mo to 4yrs of Age) With Partial Onset Seizures.
Status: COMPLETED
Conditions: Epilepsy, Partial
Interventions: DRUG: Levetiracetam|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Platelet Rich Plasma Versus Placebo for the Treatment of Greater Trochanteric Pain Syndrome (HiPPO Trial)
Status: COMPLETED
Conditions: Greater Trochanteric Pain Syndrome
Interventions: PROCEDURE: ultrasound guided injection of Platelet rich plasma|PROCEDURE: ultrasound guided injection of Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Vestibular Rehabilitation on Trunk Kinetic and Kinematic Parameters in Patients With Multiple Sclerosis
Status: COMPLETED
Conditions: Vestibular Rehabilitation in MS
Interventions: OTHER: Cawthorne Cooksey exercise protocol|OTHER: conventional vestibular rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Selective Spinal Anaesthesia With Hyperbaric Prilocain With 2%Provides Better Perioperative Hemodynamic Stability for Patients With Peripheral Vascular Disease and Cardiac Dysfunction in Lower Limb Surgery
Status: RECRUITING
Conditions: Hemodynamic Stability
Interventions: DRUG: Bupivacaine 0.5% Injectable Solution|DRUG: Prilocaine Hydrochloride 2% Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: OTHER
Clinical trial: A Trial to Assess the Efficacy and Safety of M1 Pram P037 Prandial Insulin in Subjects With Type 1 Diabetes (T1DM)
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus
Interventions: DRUG: M1 Pram P037|DRUG: Insulin lispro
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Tests Whether a Standardized LVR Performed With the Blue Egg Device Improves Cardiopulmonary Exercise Capacity
Status: WITHDRAWN
Conditions: Congestive Heart Failure|Ischemic Cardiomyopathy|Coronary Artery Disease|Myocardial Diseases
Interventions: DEVICE: Blue Egg Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase II Neoadjuvant Study of Apalutamide, Abiraterone Acetate, Prednisone, Degarelix and Indomethacin in Men With Localized Prostate Cancer Pre-prostatectomy
Status: COMPLETED
Conditions: Stage III Prostate Adenocarcinoma AJCC v7|Stage III Prostate Cancer AJCC v7|Stage IV Prostate Adenocarcinoma AJCC v7|Stage IV Prostate Cancer AJCC v7
Interventions: DRUG: Abiraterone Acetate|DRUG: Apalutamide|DRUG: Degarelix|DRUG: Indomethacin|OTHER: Laboratory Biomarker Analysis|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Norursodeoxycholic Acid vs. Placebo in NASH
Status: RECRUITING
Conditions: Nonalcoholic Steatohepatitis
Interventions: DRUG: norUrsodeoxycholic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and PK of BTK Inhibitor DTRMWXHS-12 in Patients With B-Cell Lymphomas
Status: COMPLETED
Conditions: Chronic Lymphocytic Leukemia|B-cell Lymphomas
Interventions: DRUG: DTRMWXHS-12
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single Dose Crossover Comparative Bioavailability Study of Bupropion Hcl MR Tablet 300mg
Status: COMPLETED
Conditions: Bioequivalence
Interventions: DRUG: Bupropion HCl MR tablets 300mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Safety of Navoximod and NLG802 With Stereotactic Body Radiotherapy (SBRT) Treatment of Advanced Solid Tumors
Status: WITHDRAWN
Conditions: Advanced Solid Tumors
Interventions: RADIATION: Stereotactic Body Radiotherapy (SBRT)|DRUG: navoximod|DRUG: NLG802 (indoximod Prodrug)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study of Rituximab for the Anticoagulation Resistant Manifestations of Antiphospholipid Syndrome
Status: COMPLETED
Conditions: Antiphospholipid Syndrome
Interventions: DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Therapeutic Fasting and Specific Diet in Patients With Rheumatoid Arthritis
Status: TERMINATED
Conditions: Rheumatoid Arthritis
Interventions: OTHER: Fasting and plant-based nutrition|OTHER: Standard Nutrition Counselling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pilot Study Evaluating the Safety and Efficacy of a Patient-Specific Enteroatmospheric Fistula Isolation and Management Device Independent of Negative Pressure Wound Therapy
Status: COMPLETED
Conditions: Fistula|Abdominal Injury|Negative Pressure Wound Therapy
Interventions: DEVICE: 3D printed EAF management device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Relative Bioavailability of a Pediatric Granule Formulation of Ozanimod in Healthy Adult Subjects
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Ozanimod|DRUG: Ozanimod
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Safety, Tolerability, and Pharmacokinetics of Single Doses BI 425809
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BI 425809 PfOS|DRUG: Placebo|DRUG: Placebo|DRUG: BI 425809 tablet|DRUG: BI 425809 PfOS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Loading With the P2Y12 Inhibitor Ticagrelor or Clopidogrel to Halt Ischemic Events in Patients Undergoing Elective Coronary Stenting
Status: COMPLETED
Conditions: Coronary Artery Disease|Myocardial Ischemia|Myocardial Infarction|Stent Thrombosis|Cardiovascular Diseases
Interventions: DRUG: Ticagrelor|DRUG: Clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hypofractionated Radiation Therapy to Improve Immunotherapy Response in Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Non Small Cell Lung Cancer Metastatic
Interventions: RADIATION: Radiation|DRUG: Immuno-Therapeutic Agent
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy in Treating Children With Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: BIOLOGICAL: filgrastim|DRUG: cyclophosphamide|DRUG: cytarabine|DRUG: daunorubicin hydrochloride|DRUG: doxorubicin hydrochloride|DRUG: etoposide|DRUG: leucovorin calcium|DRUG: methotrexate|DRUG: pegaspargase|DRUG: prednisone|DRUG: thioguanine|DRUG: vincristine sulfate|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Liver Cirrhosis Due to Hepatitis B Virus With Fuzheng Huayu and Entecavir
Status: UNKNOWN
Conditions: Liver Cirrhosis Due to Hepatitis B Virus
Interventions: DRUG: Entecavir + Placebo|DRUG: Entecavir + Fuzheng Huayu Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bladder Preservation for Patients With Muscle Invasive Bladder Cancer (MIBC) With Variant Histology
Status: NOT_YET_RECRUITING
Conditions: Muscle-Invasive Bladder Carcinoma|Tumor
Interventions: DRUG: Trimodal therapy (TMT) within 45 days of neoadjuvant chemotherapy (NAC)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial to Study the Effects of Revamilast in Patients With Chronic Persistent Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Revamilast|DRUG: Revamilast|DRUG: Revamilast|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: TRF-1101 Assessment in Sickle Cell Disease
Status: TERMINATED
Conditions: Sickle Cell Disease
Interventions: DRUG: TRF-1101|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Chemo-immunotherapy in Patients With Resectable Merkel Cell Carcinoma Prior to Surgery
Status: RECRUITING
Conditions: Merkel Cell Carcinoma
Interventions: DRUG: Retifanlimab|DRUG: Cisplatin|DRUG: Etoposide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Evaluation of the Response of Large B Cell Non Hodgkin's Lymphoma to Chemotherapy by PET/CT
Status: UNKNOWN
Conditions: Lymphoma, Large-Cell
Interventions: PROCEDURE: PET/CT 20 days after the first cycle of chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect Study of Marine Protein Hydrolysates to Prevent Loss of Muscle Mass and Physical Function in Frail Elderly
Status: COMPLETED
Conditions: Sarcopenia
Interventions: DIETARY_SUPPLEMENT: Marine Protein hydrolysate|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Desflurane Versus Sevoflurane Versus Propofol on Postoperative Delirium
Status: RECRUITING
Conditions: Postoperative Delirium|Major Noncardiac Surgery|Postoperative Cognitive Dysfunction
Interventions: DRUG: Desflurane|DRUG: Sevoflurane|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate Safety, Tolerability and Preliminary Efficacy of FP-1305 in Cancer Patients (MATINS)
Status: COMPLETED
Conditions: Cancer
Interventions: BIOLOGICAL: FP-1305 (bexmarilimab)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antiangiogenic Therapy for Children With Recurrent Medulloblastoma, Ependymoma and ATRT
Status: RECRUITING
Conditions: Medulloblastoma Recurrent|Ependymoma Recurrent|ATRT Recurrent
Interventions: DRUG: Bevacizumab|DRUG: Thalidomide|DRUG: Celecoxib|DRUG: Fenofibric acid|DRUG: Etoposide|DRUG: Cyclophosphamide|DRUG: Etoposide phosphate|DRUG: Cytarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Botulinum Toxin Urethral Sphincter Injection for Dysfunctional Voiding
Status: COMPLETED
Conditions: Dysfunctional Voiding
Interventions: DRUG: Botulinum toxin A|DRUG: Normal saline instillation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Fabrication of Sequential Naso-Alveolar Molding Appliances in the Treatment of Cleft Lip/Nose Deformities
Status: WITHDRAWN
Conditions: Cleft Lip|Congenital Nose Malformation|Deformity|Nose Deformities, Acquired
Interventions: PROCEDURE: Cleft Lip/Nose Repair without PSIO|PROCEDURE: Presurgical Infant Orthopedic Therapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Performance of Tension Free Vaginal Mesh (Prolift) Versus Conventional Vaginal Prolapse Surgery in Recurrent Prolapse.
Status: COMPLETED
Conditions: Pelvic Organ Prolapse
Interventions: DEVICE: Tensionfree vaginal mesh kit (Prolift)|PROCEDURE: classic vaginal prolapse surgery (fascia plication)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Translational Science Institute (CTSI) Brain HQ Modules vs. Active Controls for Elderly Survivors of ICU
Status: TERMINATED
Conditions: Neurocognitive Disorders
Interventions: BEHAVIORAL: Brain HQ Cognitive Modules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: FOLFIRI Alone Versus FOLFIRI Plus Bevacizumab Versus FOLFIRI Plus E7820 as Second-Line Therapy in Patients With Locally Advanced or Metastatic Colorectal Cancer
Status: TERMINATED
Conditions: Colorectal Cancer
Interventions: DRUG: FOLFIRI|DRUG: E7820|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Extended Reality Behavioral Activation: An Intervention for Major Depressive Disorder
Status: COMPLETED
Conditions: Major Depressive Disorder|MDD|Depression
Interventions: BEHAVIORAL: Extended Reality-Enhanced Behavioral Activation|BEHAVIORAL: Traditional Behavioral Activation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neurophysiological and Functional Mechanisms of Motor Control and Learning
Status: COMPLETED
Conditions: Transcranial Direct Current Stimulation
Interventions: PROCEDURE: tDCS-NeuroConn.|PROCEDURE: TMS - Magstim.|PROCEDURE: Sham tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety, Tolerability, Pharmacokinetics And Measurement Of Whole Blood Activity (WBA) Of PNU-100480 After Multiple Oral Doses In Healthy Adult Volunteers
Status: COMPLETED
Conditions: Tuberculosis
Interventions: DRUG: PNU-100480|DRUG: Placebo|DRUG: PNU-100480|DRUG: Placebo|DRUG: PNU-100480|DRUG: Placebo|DRUG: PNU-100480|DRUG: Placebo|DRUG: PNU-100480|DRUG: Placebo|DRUG: PNU-100480|DRUG: Placebo|DRUG: Linezolid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Safety and Performance of New 2-piece Ostomy Product Concept Compared With SenSura Click in Subjects With Ileostomy
Status: COMPLETED
Conditions: Subjects With an Ileostomy
Interventions: DEVICE: Coloplast A|DEVICE: Coloplast B|DEVICE: Coloplast C|DEVICE: SenSura Click
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Blue Star Cares: Innovative Approaches to Helping Military-Connected Caregivers
Status: COMPLETED
Conditions: Military Family|Mental Health Disorder|Social Skills|Social Isolation|Communication|Quality of Life
Interventions: BEHAVIORAL: avatar-based training
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to Determine the Activity of Robatumumab (SCH 717454) in Participants With Relapsed Osteosarcoma or Ewing's Sarcoma (MK-7454-002/P04720)
Status: TERMINATED
Conditions: Osteosarcoma|Sarcoma, Ewing's|Peripheral Neuroectodermal Tumor
Interventions: BIOLOGICAL: robatumumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing the Efficacy of Endoscopic FNA vs FNB in Diagnosing Solid Gastrointestinal Lesions
Status: UNKNOWN
Conditions: Pancreatic Tumor|Gastric Tumor|Esophageal Tumor|Lymphadenopathy|Duodenal Tumor
Interventions: PROCEDURE: Endoscopic ultrasound guided needle tissue acquisition.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Biomarkers in Acute Graft-Versus-Host Disease and Extracorporeal Photopheresis Added to Investigator Chosen Therapies of Steroid Refractory Acute GVHD
Status: TERMINATED
Conditions: Chronic Graft vs. Host Disease|Graft vs Host Disease|Graft-Versus-Host Disease
Interventions: PROCEDURE: Extracorporeal Photopheresis (ECP)|DRUG: Methoxsalen
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility of 18F-Fluciclovine PET/CT to Identify Brain Metastasis
Status: RECRUITING
Conditions: Brain Metastases
Interventions: DIAGNOSTIC_TEST: 18F-Fluciclovine (Axumin) PET/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Thirst-guided Subject-controlled Rehydration in Healthy Volunteers
Status: UNKNOWN
Conditions: Dehydration Hypertonic
Interventions: DEVICE: Patient controlled fluid device administering high volume thirst guided fluid bolus|DEVICE: Patient controlled fluid device administering low volume thirst guided fluid bolus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Tripterygium Wilfordii Hook F (TwHF) Treatment for Immune Non-responders With HIV-1 Infection
Status: UNKNOWN
Conditions: Human Immunodeficiency Virus
Interventions: DRUG: TwHF|DRUG: placebo treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Clinical and Basic Researches Related to ZhenQi Buxue Oral Liquid in Treating Menstrual Disorders
Status: UNKNOWN
Conditions: Menstrual Disorders
Interventions: DRUG: ZhenQi BuXue KouFuYe|DRUG: Progesterone Capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Efficacy of ACZ885 on Leg Artery Structure in Patients With Peripheral Artery Disease
Status: TERMINATED
Conditions: Peripheral Artery Disease
Interventions: DRUG: Canakinumab (ACZ885)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Reduced-volume PEG Bowel Preparation Administered the Same Day of Colonoscopy
Status: COMPLETED
Conditions: Colonic Polyps|Cancer Colon|Inflammatory Bowel Disease
Interventions: DRUG: polyethylene glycol (PEG)|DRUG: PEG low volume with bisacodyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Feasibility of VMAT and CBCT for Head and Neck Carcinomas
Status: COMPLETED
Conditions: Head and Neck Carcinoma
Interventions: RADIATION: VMAT with CBCT|RADIATION: VMAT with kV-ray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radiation Therapy in Treating Patients With Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer|Psychosocial Effects of Cancer and Its Treatment|Radiation Toxicity|Sexual Dysfunction
Interventions: RADIATION: 36.25 Gy IMRT|RADIATION: 51.6 Gy IMRT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of the Iconic Therapy for Borderline Personality Disorder Symptoms
Status: COMPLETED
Conditions: Personality Disorder, Borderline
Interventions: BEHAVIORAL: Emotional regulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effects of Ivabradine in Patients With Stable Coronary Artery Disease Without Clinical Heart Failure
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DRUG: Ivabradine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lung-MAP: Biomarker-Targeted Second-Line Therapy in Treating Patients With Recurrent Stage IV Squamous Cell Lung Cancer
Status: COMPLETED
Conditions: Recurrent Squamous Cell Lung Carcinoma|Stage IV Squamous Cell Lung Carcinoma AJCC v7
Interventions: DRUG: Docetaxel|BIOLOGICAL: Durvalumab|DRUG: Erlotinib Hydrochloride|DRUG: FGFR Inhibitor AZD4547|BIOLOGICAL: Ipilimumab|OTHER: Laboratory Biomarker Analysis|BIOLOGICAL: Nivolumab|DRUG: Palbociclib|OTHER: Pharmacological Study|BIOLOGICAL: Rilotumumab|DRUG: Talazoparib|DRUG: Taselisib|BIOLOGICAL: Tremelimumab
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: CM4620 Injectable Emulsion Versus Supportive Care in Patients With Acute Pancreatitis and SIRS
Status: COMPLETED
Conditions: Acute Pancreatitis|Systemic Inflammatory Response Syndrome
Interventions: DRUG: CM4620 Injectable Emulsion (Low Dose)|DRUG: CM4620 Injectable Emulsion (High Dose)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Liraglutide on Automated Closed-loop Glucose Control in Type 1 Diabetes
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: DEVICE: ePID closed loop system|DRUG: liraglutide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Individualized (fMRI-guided) TMS Treatment for Depression
Status: RECRUITING
Conditions: Depression|Major Depressive Disorder|Persistent Depressive Disorder
Interventions: DEVICE: Transcranial Magnetic Stimulation (TMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: This Study Tests Whether Taking the Medicines Empagliflozin, Linagliptin, and Metformin Together in 1 Pill is the Same as Taking Them in Separate Pills. The Study is Done in Healthy Men and Women and Measures the Amount of Each Medicine in the Blood
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Empagliflozin/linagliptin/metformin HCl|DRUG: Empagliflozin|DRUG: Linagliptin|DRUG: Metformin HCl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical and Radiographic Outcomes of Partial Pulpotomy Procedure in Primary Molars Utilizing Different Capping Materials and Different Restorative Methods
Status: RECRUITING
Conditions: Pulp Disease, Dental
Interventions: PROCEDURE: partial pulpotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Analgesic Strategies in Newborns Receiving Prostaglandin Therapy
Status: TERMINATED
Conditions: Pain
Interventions: DRUG: acetaminophen and nalbuphine|DRUG: acetaminophen and morphine|DRUG: acetaminophen and reduced dosage of prostaglandin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early or Delayed Intervention of Brain Radiotherapy Combined With Almonertinib in EGFR Mutated NSCLC With Brain Metastases
Status: RECRUITING
Conditions: Brain Metastases|Radiotherapy|EGFR Activating Mutation
Interventions: RADIATION: brain radiotherapy|DRUG: Almonertinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Safety of Sphenopalatine Ganglion Pulsed Radiofrequency Treatment for Cluster Headache
Status: COMPLETED
Conditions: Cluster Headache
Interventions: PROCEDURE: Pulsed Radiofrequency treatment|PROCEDURE: Nerve Block treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Automated Inferior Vena Cava Collapsibility Index Fluid Responsiveness in Ventilated Patients After Cardiac Surgery.
Status: UNKNOWN
Conditions: Hemodynamic Monitoring|ICU|Cardiac Surgery
Interventions: DIAGNOSTIC_TEST: Automated echocardiographic inferior vena cava measurement
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effective Communication to Improve Decision Making About Health Care Plans
Status: COMPLETED
Conditions: Health Literacy|Health Insurance|Health Services Accessibility
Interventions: BEHAVIORAL: Plain Language|BEHAVIORAL: Plain Language + Visuals|BEHAVIORAL: Plain Language + Narratives
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Resistance Training and Hydrolyzed Collagen Supplementation in Middle-aged Adults
Status: COMPLETED
Conditions: Diet|Food|Nutrition
Interventions: DIETARY_SUPPLEMENT: Resistance training with collagen supplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Supportive Release Center Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Mental Health|Mental Health Services|Substance Use|Continuity of Patient Care|Recidivism
Interventions: BEHAVIORAL: TASC Service Linkages - Discharge Area Only|BEHAVIORAL: SRC Overnight Stay|BEHAVIORAL: TASC Services Linkages - SRC Onsite|BEHAVIORAL: APN Appointment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Prevention and Treatment of Reperfusion Injury After Mechanical Thrombectomy in Acute Ischemic Stroke
Status: RECRUITING
Conditions: Stroke Patients
Interventions: DRUG: Antihypertensive drugs (no restriction on the type of drugs)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: An Effectiveness and Safety Study of ELMIRON (Pentosan Polysulfate Sodium) for the Treatment of Chronic Non-Bacterial Inflammation of the Prostate Gland
Status: COMPLETED
Conditions: Prostatitis
Interventions: DRUG: pentosan polysulfate sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Low Pulse Amplitude Focal ECT (LAP Study)
Status: COMPLETED
Conditions: Depression
Interventions: DEVICE: spectrum 5000Q ECT device (RUL ECT)|DEVICE: spectrum 5000Q ECT device (RUL LAP ECT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SBRT in Multi-metastatic NSCLC Patients Which Are Pan-negative for Driver Mutations
Status: UNKNOWN
Conditions: NSCLC|SBRT|GM-CSF
Interventions: RADIATION: SBRT concurrent with GM-CSF|DRUG: two-drug chemotherapy containing platinum, including carboplatin/Cisplatin + pemetrexed/docetaxel/paclitaxel/etoposide/gemcitabine/vinorelbine/albumin-bound paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Apremilast in Combination With Clobetasol Spray for the Treatment of Plaque Psoriasis
Status: UNKNOWN
Conditions: Psoriasis
Interventions: COMBINATION_PRODUCT: Apremilast and Clobetasol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acute-phase Response & Periodontal Treatment in Patients With Hypertension
Status: COMPLETED
Conditions: Periodontitis|Hypertension
Interventions: PROCEDURE: FM-SRP|PROCEDURE: Q-SRP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Probiotic Yogurt in the Treatment of Acute Diarrhea in Children
Status: COMPLETED
Conditions: Acute Diarrhea|Acute Gastroenteritis
Interventions: DIETARY_SUPPLEMENT: Probiotic yogurt|DRUG: Placebo probiotic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Humoral and Cellular Immune Response of Herpes Simplex (gD) Candidate Vaccines From 2 Different Cell Lines
Status: COMPLETED
Conditions: Prophylaxis Herpes Simplex
Interventions: BIOLOGICAL: Adjuvanted herpes simplex (gD) candidate vaccine GSK 208141|BIOLOGICAL: Herpes simplex virus containing gD-Alum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety and Effects on Responses to Stress and Pain of Natural Medical Marijuana Products
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Active CBD/THC Dose 1|DRUG: Active CBD/THC Dose 2|DRUG: matched placebo comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intrapleural AdV-tk Therapy in Patients With Malignant Pleural Effusion
Status: COMPLETED
Conditions: Malignant Pleural Effusion|Lung Cancer|Mesothelioma|Breast Cancer|Ovarian Cancer
Interventions: BIOLOGICAL: AdV-tk + valacyclovir
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Covid-19 on Training for ENT and Cervico-Facial Surgery Residents in France
Status: UNKNOWN
Conditions: Cervico-Facial Surgery ENT Academic Medical and Surgical Training in France|Cervico-Facial Surgery ENT Medical Residency (Auvergne-Rhône-Alpes, Grand Est, Ile de France, Nouvelle Aquitaine and Provence-Alpes-Côte d'Azur Areas)
Interventions: OTHER: Questionnaire
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Latino MSM Focused Pre-Exposure Prophylaxis Uptake Intervention
Status: UNKNOWN
Conditions: HIV
Interventions: BEHAVIORAL: Estoy PrEParado/ I am PrEPared intervention|BEHAVIORAL: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Temozolomide, Etoposide, Doxil, Dexamethasone, Ibrutinib, and Rituximab (TEDDI-R) in Aggressive B-cell Lymphomas With Secondary Involvement of the Central Nervous System (CNS)
Status: ACTIVE_NOT_RECRUITING
Conditions: Central Nervous System Lymphoma|Secondary Central Nervous System Lymphoma
Interventions: DRUG: TEDD-R|DRUG: TEDDI-R|DRUG: Ibrutinib|DRUG: Cytarabine|DRUG: Isavuconazole|DRUG: Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Minnesota Inclusive LTSS for LGBTQ Seniors
Status: RECRUITING
Conditions: Alzheimer Disease|Dementia
Interventions: OTHER: Training to Serve (TTS) in person training|OTHER: Training to Serve online training (eTTS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Monoclonal Antibody Therapy in Treating Patients With Myelodysplastic Syndrome or Relapsed or Refractory Acute Myeloid Leukemia or Chronic Myelogenous Leukemia
Status: COMPLETED
Conditions: Leukemia|Myelodysplastic Syndromes
Interventions: BIOLOGICAL: lintuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Inhaled Budesonide in Very Preterm Infants at Risk for Bronchopulmonary Dysplasia
Status: COMPLETED
Conditions: Bronchopulmonary Dysplasia
Interventions: DRUG: Budesonide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Fluoroscopic Analysis of Total Knee Replacement With a Kinematic Retaining or a Posterior Stabilized Design
Status: COMPLETED
Conditions: Total Knee Replacement
Interventions: DEVICE: Physica KR|DEVICE: Physica PS
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Role of Elastin Metabolites in Aortic Remodelling in AS
Status: COMPLETED
Conditions: Aortic Stenosis
Interventions: DIAGNOSTIC_TEST: ECG|DIAGNOSTIC_TEST: Blood test and biobanking|DIAGNOSTIC_TEST: Trans-thoracic Echocardiogram|DIAGNOSTIC_TEST: Vicorder recording|DIAGNOSTIC_TEST: Magnetic Resonance Imaging
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Fast-Track Colorectal Surgery in Senior Patients
Status: UNKNOWN
Conditions: Colorectal Disorders
Interventions: DIETARY_SUPPLEMENT: Preoperative Carbohydrate load|PROCEDURE: individualized i.v fluids therapy|BEHAVIORAL: Fasting state after midnight|BEHAVIORAL: No Nasogastric tube postoperatively|BEHAVIORAL: urinary catheter removal|BEHAVIORAL: Oral liquids|BEHAVIORAL: Stimulation of inspirex utilization|BEHAVIORAL: Mobilization|OTHER: Preanesthetic medication
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Physiological Study to Assess Mechanism of Action of MOBIDERM® in Lower-limb Lymphedema Patients
Status: COMPLETED
Conditions: Lymphedema of Leg|Lymphedema Congenital|Lymphedema Primary|Lymphedema, Secondary
Interventions: DEVICE: MOBIDERM® autofit : auto-adjustable compression stocking
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: COVID-19 Seroconversion Among Front Line Medical and Paramedical Staff in Emergency, Intensive Care Units and Infectious Disease Departments During the 2020 Epidemic
Status: COMPLETED
Conditions: Sars-CoV2
Interventions: OTHER: blood sample
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: HYdrocortisone and VAsopressin in Post-RESuscitation Syndrome
Status: RECRUITING
Conditions: Postresuscitation Syndrome
Interventions: DRUG: Administration of AVP|DRUG: Administration of placebo AVP|DRUG: Administration of placebo hydrocortisone|DRUG: Administration of hydrocortisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intravenous Erwinia Chrysanthemi Asparaginase in Patients With Newly Diagnosed Philadelphia Chromosome Negative Acute Lymphoblastic Leukemia Aged 60 Years or Older
Status: WITHDRAWN
Conditions: Acute Lymphoblastic Leukemia (ALL)|Newly Diagnosed Philadelphia Chromosome Negative|Aged 60 Years or Older
Interventions: DRUG: Erwinia Chrysanthemi asparaginase
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: In Vivo Preoperative Skin Preparation Efficacy Study Within a Defined Product Coverage Area
Status: COMPLETED
Conditions: Surgical Skin Preparation|Surgical Procedure, Unspecified
Interventions: DRUG: 3M CHG/IPA Prep
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study Comparing the Efficacy of TCbHP and ECHP-THP in the Neoadjuvant Treatment of HER2-positive Breast Cancer
Status: WITHDRAWN
Conditions: Breast Cancer|HER2-positive Breast Cancer
Interventions: DRUG: Docetaxel + Carboplatin + Trastuzumab + Pertuzumab|DRUG: (Epirubicin + Cyclophosphamide - Docetaxel) + (Trastuzumab + Pertuzumab)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Study of KW-0761 in Subjects With CCR4-positive Adult T-cell Leukemia-lymphoma
Status: COMPLETED
Conditions: Adult T-cell Leukemia-lymphoma
Interventions: BIOLOGICAL: KW-0761
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Two Different Intravenous Lipid Emulsions on the Outcomes of Preterm Infants With Sepsis
Status: COMPLETED
Conditions: Sepsis Newborn
Interventions: DRUG: Smoflipid ®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Phase III Trial of Anaplastic Glioma Without 1p/19q Loss of Heterozygosity (LOH)
Status: ACTIVE_NOT_RECRUITING
Conditions: Brain and Central Nervous System Tumors
Interventions: DRUG: temozolomide|GENETIC: DNA methylation analysis|OTHER: laboratory biomarker analysis|PROCEDURE: adjuvant therapy|PROCEDURE: quality-of-life assessment|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Using a Low Dose of Ketamine vs. Active Placebo in Treating Severe Depression and Suicide
Status: UNKNOWN
Conditions: Major Depressive Disorder
Interventions: DRUG: Ketamine|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Switching TDF/FTC/EFV to TDF/FTC/RPV VS Continuing TDF/FTC/EFV in HIV Patients With Complete Virological Suppression
Status: COMPLETED
Conditions: Anti-Retroviral Agents|Efavirenz|HIV-1-infection|Sustained Virologic Response|Dyslipidemias|Rilpivirine
Interventions: DRUG: Tenofovir/Emtricitabine/Rilpivirine|DRUG: Tenofovir/Emtricitabine/Efavirenz
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 3 Randomized, Masked, Controlled Trial to Evaluate Efficacy and Safety of Belzupacap Sarotalocan (AU-011) Treatment Compared to Sham Control in Subjects With Primary Indeterminate Lesions or Small Choroidal Melanoma
Status: RECRUITING
Conditions: Choroidal Melanoma|Indeterminate Lesions|Uveal Melanoma|Ocular Melanoma
Interventions: DRUG: Belzupacap Sarotalocan|DEVICE: Suprachoroidal Microinjector|DEVICE: Infrared Laser|DEVICE: Sham Infrared Laser|DEVICE: Sham Microinjector|DRUG: Sham Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Exenatide in Obese Patients With Accelerated Gastric Emptying
Status: COMPLETED
Conditions: Obesity
Interventions: DRUG: Exenatide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Metformin for Sputum Conversion in Patients With Active Pulmonary Tuberculosis
Status: UNKNOWN
Conditions: Tuberculosis, Pulmonary
Interventions: DRUG: MetFORMIN 500 Mg Oral Tablet|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT