pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Vascular Function, Fish Protein Hydrolysates and Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: OTHER: Placebo|OTHER: Fish protein hydrolysates
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Investigate the Pharmacokinetics and Safety After Oral Administration of CKD-378 and Co-administration of D745, D150, D029 in Healthy Adults
Status: COMPLETED
Conditions: Type II Diabetes
Interventions: DRUG: CKD-378 (low-dose)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treosulfan-based Conditioning for Allogeneic Stem-cell Transplantation (SCT) in Lymphoid Malignancies
Status: UNKNOWN
Conditions: Non Hodgkin Lymphoma|Hodgkin Lymphoma
Interventions: DRUG: treosulfan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Ureteral Stents in the Management of Stone Disease
Status: TERMINATED
Conditions: Urinary Stones|Urinary Tract Stones
Interventions: DEVICE: Randomization to size 6 French soft vs. size 6 French hydrophobic ureteral stent.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Biochemical Role of Matrix Metalloproteinase -9 in Rheumatoid Arthritis
Status: NOT_YET_RECRUITING
Conditions: Rheumatoid Arthritis
Interventions: DIAGNOSTIC_TEST: conventional pcr
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Health Influences of Puberty (HIP) Study
Status: COMPLETED
Conditions: Obesity|Insulin Resistance|Gonadal Dysfunction|Type 2 Diabetes
Interventions: DRUG: Metformin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Music Therapy on Mood, Pain, Patient and Staff Satisfaction on Adult Inpatient Neurological Units
Status: COMPLETED
Conditions: Music Therapy|Pain|Patient Satisfaction|Inpatients|Affect
Interventions: OTHER: Music therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ARREST - A Phase I Study of SABR for Poly-metastatic Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Cancer
Interventions: RADIATION: Stereotactic ablative radiotherapy - Level 1|RADIATION: Stereotactic ablative radiotherapy - Level 2|RADIATION: Stereotactic ablative radiotherapy - Level 3|RADIATION: Stereotactic ablative radiotherapy - Level 4|RADIATION: Stereotactic ablative radiotherapy - De-escalation Level
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective, Randomised Multicenter Study Comparing the Efficacy of Transbronchial Forceps Biopsy With Cryobiopsy to Diagnose Interstitial Lung Disease.
Status: COMPLETED
Conditions: Interstitial Lung Disease
Interventions: PROCEDURE: transbronchial lung biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of Liposomal Bupivacaine Versus 0.25% Bupivacaine Hydrochloride Post Breast Reduction
Status: RECRUITING
Conditions: Breast Reduction
Interventions: DRUG: Bupivacaine Hydrochloride|DRUG: Liposomal Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Milk Thistle in Trichotillomania in Children and Adults
Status: COMPLETED
Conditions: Trichotillomania|Hair Pulling Disorder
Interventions: DRUG: Milk Thistle|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Local Intraoperative Steroid Administration on Post-ACDF Dysphagia
Status: COMPLETED
Conditions: Swallowing Function
Interventions: DRUG: steroid injection|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Neoadjuvant Chemo-Immunotherapy and Surgical Resection in Locally Advanced Non-small Cell Lung Cancer With N3 Lymph Node Involvement
Status: NOT_YET_RECRUITING
Conditions: Non-small Cell Lung Cancer Stage III
Interventions: DRUG: Cemiplimab-Rwlc
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Dexmedetomidine Used in Continuous Thoracic Paravertebral Blocks
Status: COMPLETED
Conditions: Post-thoracotomy Pain Syndrome
Interventions: DRUG: Dexmedetomidine|DRUG: Ropivacaine|DEVICE: Mindray M7 series
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Pelvic Floor and Hip Muscle Strengthening in the Treatment of Stress Urinary Incontinence
Status: COMPLETED
Conditions: Stress Urinary Incontinence
Interventions: OTHER: Strengthening of pelvic floor muscles.|OTHER: Strengthening of hip muscles.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare Treatment With Sirolimus Versus Standard Treatment in Patients Who Have Received a Kidney Transplant
Status: TERMINATED
Conditions: End-Stage Renal Disease|Kidney Transplantation
Interventions: DRUG: Cyclosporine|DRUG: Sirolimus|DRUG: Tacrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: JAVLOR Association Study in CDDP-unfit Patients With Advanced Transitional Cell Carcinoma: Gemcitabine Versus Carboplatin
Status: COMPLETED
Conditions: Bladder Transitional Cell Carcinoma Stage IV
Interventions: DRUG: Vinflunine, Gemcitabine|DRUG: Vinflunine, Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cognitive Remediation Therapy Within a Secure Forensic Setting
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder|Cognitive Deficits
Interventions: BEHAVIORAL: Cognitive Remediation Therapy|OTHER: Treatment as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Suction Mini-PCNL Versus Standard PCNL for the Management of 2-4cm Kidney Stones
Status: UNKNOWN
Conditions: Kidney Calculi
Interventions: PROCEDURE: suction mini percutaneous nephrolithotomy|PROCEDURE: standard percutaneous nephrolithotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrashape System in Combination With VelaShape II Device for Circumferential Reduction
Status: COMPLETED
Conditions: Abdominal Fat
Interventions: DEVICE: Ultrashape|DEVICE: Velashape II
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigating the Role and Electrophysiological Characteristics of the Human Claustrum Based on SEEG
Status: RECRUITING
Conditions: Refractory Epilepsy|Consciousness, Loss of
Interventions: OTHER: Direct Electrical Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Bioequivalence Study of Nabumetone 750 mg Tablets of Dr. Reddy's Under Fasting Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Nabumetone|DRUG: Relafen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anlotinib Plus Sintilimab as First-line Treatment for Patients With Advanced Colorectal Cancer (APICAL-CRC)
Status: COMPLETED
Conditions: Colorectal Cancer|Immunotherapy|Anlotinib|Sintilimab|Chemo-free Therapy|First-line Treatment
Interventions: DRUG: Anlotinib plus Sintilimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Monopolar Dielectric Diathermy and Therapeutic Exercise on Chronic Neck Pain and Therapeutic Exercise on Pain, Functionality, Movement Phobia on Pain, Functionality, Movement Phobia and Quality of Life of Patients of Patients With Chronic Neck Pain. Randomized Clinical Trial
Status: RECRUITING
Conditions: Chronic Pain|Neck Pain
Interventions: OTHER: Monopolar electrical diathermy plus therapeutic exercise|OTHER: Therapeutic Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Controlled Randomized Study With Athena Base Plate Versus SenSura Base Plate on Perspiring Skin
Status: COMPLETED
Conditions: Healthy
Interventions: DEVICE: SenSura|DEVICE: Athena
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of Different Helicobacter Pylori Detection Methods in Patients With Chronic Atrophic Gastritis
Status: COMPLETED
Conditions: Helicobacter Pylori Infection
Interventions: DIAGNOSTIC_TEST: Histology，13C urea breath test，Stool antigen test，Serological antibody test for H.pylori and Serologic test with a current infection marker of H.pylori|DRUG: Rabeprazole，Minocycline，Amoxicillin and Colloidal bismuth pectin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of XL228 in Subjects With Chronic Myeloid Leukemia or Philadelphia-Chromosome-Positive Acute Lymphocytic Leukemia
Status: TERMINATED
Conditions: Chronic Myeloid Leukemia|Leukemia, Lymphoblastic, Acute, Philadelphia-Positive
Interventions: DRUG: XL228
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long Term Free Living Study With Modified Foods and Type 2 Diabetics
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus|Obesity
Interventions: BEHAVIORAL: lower fat food supplied and education|BEHAVIORAL: gift cards for grocery foods and written education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of PF-06882961 in Adults With Obesity
Status: COMPLETED
Conditions: Obesity
Interventions: DRUG: Placebo (Cohorts 1 and 2)|DRUG: PF-06882961 (Cohorts 1 and 2)|DRUG: Placebo (Cohort 3)|DRUG: PF-06882961 (Cohort 3)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Characterization of the DELPhI System in Assessing Brain's Functionality in Different Neurological Disorders
Status: COMPLETED
Conditions: Stroke|TBI|Fibromyalgia|PDD|Adhd|ABD|Ptsd|Healthy|MCI|Dementia|Cognitive Impairment|Cognitive Decline
Interventions: DIAGNOSTIC_TEST: DELPhI (TMS-EEG analysis)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: An Intervention Delivered by App Instant Messaging to Increase the Acceptability of Effective Contraception Among Young People in Tajikistan
Status: COMPLETED
Conditions: Contraception
Interventions: BEHAVIORAL: Contraceptive app instant messages|OTHER: Mobile phone app
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Metanx® in Subjects With Type 2 Diabetic Peripheral Neuropathy (DPN)
Status: COMPLETED
Conditions: Type 2 Diabetic Peripheral Neuropathy (DPN)
Interventions: OTHER: Metanx (a medical food)|OTHER: Metanx placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Febrile Urinary Tract Infection Randomized Short Treatment Trial
Status: COMPLETED
Conditions: Urinary Tract Infection
Interventions: DRUG: short treatment (ciprofloxacin)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Trial to Evaluate Efficacy and Safety of Nitazoxanide in the Treatment of Mild or Moderate COVID-19
Status: COMPLETED
Conditions: COVID-19
Interventions: DRUG: Nitazoxanide|DRUG: Placebo|DIETARY_SUPPLEMENT: Vitamin Super B-Complex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Co-developing a Novel Intervention to Promote Wellbeing of Family Caregivers of Individuals With Spinal Cord Injury
Status: NOT_YET_RECRUITING
Conditions: Spinal Cord Injuries|Caregiver Burden
Interventions: OTHER: COMPANION eHealth Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Efficacy of Cesamet™ for the Treatment of Pain in Patients With Diabetic Peripheral Neuropathy
Status: COMPLETED
Conditions: Diabetic Neuropathies
Interventions: DRUG: Cesamet™ (nabilone)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PROS Brief Smoking Cessation Counseling in Pediatric Practice to Reduce Secondhand Smoke Exposure of Young Children
Status: COMPLETED
Conditions: Health Care Quality, Access, and Evaluation|Smoking Cessation
Interventions: BEHAVIORAL: training in smoking cessation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Vorinostat and Idarubicin in Treating Patients With Relapsed or Refractory Leukemia or Myelodysplastic Syndromes
Status: COMPLETED
Conditions: Acute Myeloid Leukemia With Multilineage Dysplasia Following Myelodysplastic Syndrome|Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities|Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)|Adult Acute Myeloid Leukemia With t(15;17)(q22;q12)|Adult Acute Myeloid Leukemia With t(16;16)(p13;q22)|Adult Acute Myeloid Leukemia With t(8;21)(q22;q22)|Adult Acute Promyelocytic Leukemia (M3)|Blastic Phase Chronic Myelogenous Leukemia|Myelodysplastic/Myeloproliferative Neoplasm, Unclassifiable|Previously Treated Myelodysplastic Syndromes|Recurrent Adult Acute Lymphoblastic Leukemia|Recurrent Adult Acute Myeloid Leukemia|Relapsing Chronic Myelogenous Leukemia|Secondary Acute Myeloid Leukemia|Secondary Myelodysplastic Syndromes
Interventions: DRUG: vorinostat|DRUG: idarubicin|OTHER: laboratory biomarker analysis|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Change of the Structure and Function of Taste Buds After the Otosclerosis Surgery
Status: UNKNOWN
Conditions: Chorda Tympani Disorder|Taste Disorders|Stapes Fixation
Interventions: DIAGNOSTIC_TEST: Narrow Band Imaging|DIAGNOSTIC_TEST: Tongue sensitivity testing|OTHER: Qualitiy of life|DIAGNOSTIC_TEST: Threshold change|DIAGNOSTIC_TEST: Taste
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Eye-Movement Desensitization and Post-Traumatic Syndroms
Status: COMPLETED
Conditions: Post-Concussion Symptoms|Post-Traumatic Stress Disorder
Interventions: BEHAVIORAL: R-TEP EMDR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Clinical Study to Assess a Compression Device in Patients With Venous Leg Ulcers
Status: WITHDRAWN
Conditions: Varicose Ulcer
Interventions: DEVICE: 3M™ Coban™ Custom Fit Compression System|DEVICE: Profore
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exploratory Study of the Relationships Between the Biomarkers of Inflammation, Lipidome and Insulin Resistance and Disorders of Glycemic Regulation in a Cohort of Insulin-resistant Subjects Due to Excess Weight or Dunnigan's Lipodystrophy
Status: COMPLETED
Conditions: Lipodystrophy|Dunnigan Syndrome
Interventions: OTHER: research-specific blood sample
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study of Etanercept Monotherapy vs Methotrexate Monotherapy for Maintenance of Rheumatoid Arthritis Remission
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: etanercept pre-filled syringe subcutaneous injection|DRUG: Oral methotrexate|DRUG: Placebo for etanercept subcutaneous injection|DRUG: Placebo for methotrexate|DIETARY_SUPPLEMENT: Folic acid (non-investigational product)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Tranexemic Acid Versus Norethisterone Acetate on Endometrial Vasculature .
Status: UNKNOWN
Conditions: Dysfunctional Uterine Bleeding
Interventions: DRUG: norethisterone acetate|DRUG: tranexamic acid tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Live Supervision in Psychotherapy: Study Protocol for a Single Case Experimental Design Study (SCED)
Status: ACTIVE_NOT_RECRUITING
Conditions: Competence
Interventions: BEHAVIORAL: Live Supervision + Session Goal Formulation|OTHER: Session Goal Formulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Cultivating Resilience in Oncology Practice
Status: UNKNOWN
Conditions: Childhood Cancer|Depressive Symptoms|Anxiety Disorders and Symptoms|Mental Health Issue
Interventions: BEHAVIORAL: Awareness and insight Modules (AiM)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Sodium Bicarbonate Buffered Lidocaine on the Success of IAN Block of Teeth With Irreversible Pulpitis
Status: COMPLETED
Conditions: Local Anesthesia
Interventions: DRUG: 2% lidocaine with 1:80,000 epinephrine|DRUG: sodium bicarbonate|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Study of the Effects of Transcutaneous Vagus Nerve Stimulation on Cancer Patients
Status: COMPLETED
Conditions: Breast Cancer|Cancer, Therapy-Related|Cancer-related Fatigue|Quality of Life
Interventions: DEVICE: Transcutaneous vagus nerve stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Progressive Neuromuscular Exercise Program and Taping on Muscle Strength and Pain in Patellofemoral Pain
Status: COMPLETED
Conditions: Patellofemoral Pain Syndrome|Kinesiotape|Exercise|Strength
Interventions: OTHER: progressive neuromuscular exercise program|OTHER: Exercise and Taping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Comparison of 12% Ammonium Lactate and 10% Urea Cream in Geriatric With Xerosis Cutis
Status: COMPLETED
Conditions: Xerosis Cutis
Interventions: DRUG: Ammonium Lactate|DRUG: Urea
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects and Mechanisms of Mindfulness Intervention for Emotional Distress: Daily Interventions and Daily Assessments
Status: NOT_YET_RECRUITING
Conditions: Emotional Distress
Interventions: BEHAVIORAL: internet-based mindfulness intervention for emotional distress(iMIED）
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial Evaluating the Efficacy, Safety, and Tolerability of Cariprazine in a Dose-Reduction Paradigm in the Prevention of Relapse in Participants With Schizophrenia
Status: TERMINATED
Conditions: Schizophrenia
Interventions: DRUG: Cariprazine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Effect of Honey Supplementation on Serum Leptin in Malnourished Infants and Children
Status: COMPLETED
Conditions: Malnourished Infants and Childern
Interventions: DIETARY_SUPPLEMENT: honey supplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Multicenter, Randomized Placebo Controlled Pilot MicroCT Study to Estimate the Effect of Treatment With Denosumab (AMG 162) and Alendronate Sodium in Postmenopausal Women With Low Bone Mineral Density
Status: COMPLETED
Conditions: Postmenopausal Osteoporosis
Interventions: DRUG: Alendronate|DRUG: Denosumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Management of Mineral and Bone Disease in Hemodialysis-Calcitriol vs. Paricalcitol
Status: TERMINATED
Conditions: Kidney Failure|Secondary Hyperparathyroidism|Hyperphosphatemia|Hypercalcemia
Interventions: DRUG: Calcitriol|DRUG: Paricalcitol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Active Choice Intervention About Physical Activity for Physically Inactive Adults
Status: COMPLETED
Conditions: Physical Activity
Interventions: BEHAVIORAL: Guideline + Active Choice + action&coping planning (GA+)|BEHAVIORAL: Guideline + Active Choice (GA)|BEHAVIORAL: Guideline + information (GI)|BEHAVIORAL: Guideline (G)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Peptide Vaccinations Plus GM-CT-01 in Melanoma
Status: TERMINATED
Conditions: Metastatic Melanoma
Interventions: BIOLOGICAL: Tumor specific peptides: MAGE-3.A1 and / or NA17.A2|BIOLOGICAL: Galectin-3 inhibitor: GM-CT-01 systemic injections|BIOLOGICAL: Galectin-3 inhibitor: GM-CT-01 Peri-tumoral administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fed Study of Terbinafine Hydrochloride Tablets 250 mg and Lamisil® 250 mg
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Terbinafine Hydrochloride Tablets 250 mg|DRUG: Lamisil® Tablets 250 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Safety Study of Carotid Body Neurostimulation to Treat Cerebral Vasospasm
Status: UNKNOWN
Conditions: Aneurysmal Subarachnoid Hemorrhage|Cerebral Vasospasm
Interventions: DEVICE: Delta system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diagnostic Accuracy of Dual-energy CT
Status: COMPLETED
Conditions: Osteoarthritis|Hand Osteoarthritis|Crystal; Deposit Joint|Crystals; Arthritis, Pyrophosphate|Crystals; Arthritis, Hydroxyapatite|Crystal Arthritis|Crystal Arthropathy of Hand
Interventions: RADIATION: CT-scanning
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Sleep Apnea in TIA/Stroke: Reducing Cardiovascular Risk With Positive Airway Pressure
Status: COMPLETED
Conditions: Transient Ischemic Attack|Stroke
Interventions: DEVICE: Standard CPAP Intervention|BEHAVIORAL: Enhanced CPAP Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ibrutinib and Standard Immuno-Chemotherapy in Younger, High-Risk Patients With Diffuse Large B-Cell Lymphoma
Status: COMPLETED
Conditions: Diffuse Large B Cell Lymphoma
Interventions: DRUG: Ibrutinib Oral Capsule [Imbruvica]|DRUG: R-CHOEP chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PD-1(Programmed Death-1) Antibody +GP as First Line Treatment for Triple Negative Breast Cancer(TNBC) Patients
Status: UNKNOWN
Conditions: Triple Negative Breast Cancer
Interventions: COMBINATION_PRODUCT: JS001 120mg+GP|COMBINATION_PRODUCT: JS001 240mg+GP|COMBINATION_PRODUCT: JS001 480mg+GP|COMBINATION_PRODUCT: GP followed by JS001
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Compare Safety and Pharmacokinetic Properties of Surfolase Capsule(Acebrophylline 100mg) and Surfolase CR(200mg)
Status: COMPLETED
Conditions: Healthy Male
Interventions: DRUG: Surfolase capsule (100mg)|DRUG: Surfolase CR (200mg, T1)|DRUG: Surfolase CR (200mg, T3)|DRUG: Surfolase CR (200mg, T4)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Targeting TFPI With Concizumab to Improve Haemostasis in Glanzmann Thrombasthenia Patients: an in Vitro Study
Status: COMPLETED
Conditions: Glanzmann Thrombasthenia
Interventions: OTHER: Clot formation in whole blood under flow in a microfluidic flow chamber coated with tissue factor and collagen|OTHER: : PRP viscoelastic changes under clot formation measured by thromboelastometry using RoTEM|OTHER: Thrombin Generation Assay (TGA) in PRP using TF trigger|OTHER: Global fibrinolytic capacity in PRP using reagents for in vitro triggering of the clot and its lysis|OTHER: Concizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, Pharmacokinetics and Target Engagement of GSK3858279 in Healthy Caucasian, Chinese and Japanese Participants
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: GSK3858279|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial of Tadalafil in Patients With Squamous Cell Carcinoma of the Upper Aero Digestive Tract
Status: COMPLETED
Conditions: Head and Neck Squamous Cell Carcinoma
Interventions: DRUG: Tadalafil|OTHER: Placebo Pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: "Pilot Study: Effects of Vibration on Postoperative Early Mobilization of Cardiac Surgery Patients"
Status: RECRUITING
Conditions: Cardiovascular Risk Factor|Frailty
Interventions: OTHER: Vibration Plate|OTHER: Tilt at 15°|OTHER: Standard hospital mobilization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of Self-made Fetal Movement and Position Tracking on Prenatal Attachment and Pregnancy Distress
Status: COMPLETED
Conditions: Prenatal Attachment|Fetal Position Tracking|Distress
Interventions: BEHAVIORAL: Experimental
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Neoadjuvant Plus Adjuvant or Only Adjuvant Nab- Paclitaxel Plus Gemcitabine for Resectable Pancreatic Cancer
Status: COMPLETED
Conditions: Resectable Pancreatic Cancer|Ductal Adenocarcinoma of the Pancreas
Interventions: DRUG: perioperative nab-paclitaxel/gemcitabine|DRUG: adjuvant nab-paclitaxel/gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Timing of Maternal Antibiotic Prophylaxis During a Cesarean Section and the Early Infant Gut Microbiome
Status: COMPLETED
Conditions: Microbial Colonization|Antibiotic Side Effect|Cesarean Section Complications
Interventions: DRUG: Cefazolin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Omega-3 Monoglyceride Based Topic Products as Skin Prebiotics for Eczema
Status: RECRUITING
Conditions: Eczema
Interventions: COMBINATION_PRODUCT: Omega-3 monoglyceride based topical Serum and cream of formulation A (light)|COMBINATION_PRODUCT: Omega-3 monoglyceride based topical Serum and cream of formulation B (rich)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: REACH (Restore Energy, Activity Can Help) Lupus Study
Status: RECRUITING
Conditions: Systemic Lupus Erythematosus|Fatigue
Interventions: BEHAVIORAL: REACH Peer Coaching Program|BEHAVIORAL: REACH Mobile Health Application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Double-Blind, Randomized, Single Dose Escalation Safety Study of Intraarticular Bone Morphogenic Protein (38A BMP-7) in Subjects With Osteoarthritis (OA) of the Knee
Status: COMPLETED
Conditions: Osteoarthritis of the Knee
Interventions: DRUG: Bone morphogenetic protein 7
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Patient Preference for Oral or Intravenous Vinorelbine in the Treatment of Advanced NSCLC
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer Metastatic
Interventions: DRUG: Vinorelbine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Novel Robotic System for Single Port and Natural Orifice Transluminal Endoscopic Surgery
Status: COMPLETED
Conditions: Colorectal Neoplasms|Urologic Neoplasms|Urologic Diseases|Nasopharyngeal Neoplasms|Oropharyngeal Neoplasms|Oral Neoplasms|Hypopharyngeal Neoplasms|Laryngeal Neoplasms|ENT Diseases
Interventions: PROCEDURE: Robotic single port surgery and NOTES
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Different Regimens for Eradication of Helicobacter Pylori in Kuwait
Status: COMPLETED
Conditions: Helicobacter Pylori Infection
Interventions: DRUG: Omeprazole, Amoxicillin, Metronidazole and Clarithromycin|DRUG: Omeprazole, Amoxicillin and Clarithromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Daily Consumption of Orange Maize on Breast Milk Retinol in Lactating Zambian Women
Status: COMPLETED
Conditions: Vitamin A Deficiency
Interventions: OTHER: white maize and a corn oil capsule|OTHER: orange maize and a corn oil capsule|OTHER: white maize and a vitamin A capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose:
Clinical trial: Sorafenib in Treating Patients With Recurrent or Progressive Malignant Glioma
Status: COMPLETED
Conditions: Adult Anaplastic Astrocytoma|Adult Anaplastic Oligodendroglioma|Adult Giant Cell Glioblastoma|Adult Gliosarcoma|Recurrent Adult Brain Tumor
Interventions: DRUG: sorafenib tosylate|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nexalin Therapy for the Treatment of Depressive Symptoms
Status: COMPLETED
Conditions: Depression
Interventions: DEVICE: Nexalin 1.3mA Device|DEVICE: Nexalin 15mA device|DRUG: placebo device and Citalopram
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Long Term Safety Study of Suvorexant in Participants With Primary Insomnia (MK-4305-009 AM3)
Status: COMPLETED
Conditions: Insomnia
Interventions: DRUG: Suvorexant|DRUG: Dose-matched Placebo to Suvorexant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility of the ANDAGO System in Pediatric Neurorehabilitation
Status: COMPLETED
Conditions: Central Motor Disorders|Orthopedic Disorders
Interventions: DEVICE: ANDAGO|DEVICE: ANDAGO|DEVICE: ANDAGO|DEVICE: ANDAGO|DEVICE: ANDAGO
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: LCC-CARIS-01: Molecular Profiling in Gynaecological Cancer
Status: COMPLETED
Conditions: Epithelial Ovarian Cancer|Peritoneal Cancer|Fallopian Tube Cancer|Gynaecological Malignancy
Interventions: OTHER: Diagnostic analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Combined Cognitive and Vocational Interventions After Mild-to-moderate TBI: a Randomized Controlled Trial
Status: COMPLETED
Conditions: Brain Injuries, Traumatic|Cognitive Impairment
Interventions: BEHAVIORAL: Combined cognitive (Compensatory Cognitive Training - CCT) and vocational rehabilitation (Supported Employment)|BEHAVIORAL: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Probiotics in Neonatal Hyperbilirubinemia
Status: UNKNOWN
Conditions: Hyperbilirubinemia, Neonatal
Interventions: DRUG: Probiotic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Renal Protective Effect (Urine Albumin-to-Creatinine Ratio (UACR)), Efficacy and Safety of Ipragliflozin in Type 2 Diabetes Mellitus Patients With Albuminuria
Status: TERMINATED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: metformin|DRUG: ipragliflozin|DRUG: glimepiride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Vanoxerine for Conversion of Atrial Fibrillation or Flutter to Normal Sinus Rhythm
Status: COMPLETED
Conditions: Symptomatic Atrial Fibrillation|Atrial Flutter
Interventions: DRUG: Vanoxerine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Combination of Avelumab and Taxane (AVETAX) for Urothelial Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Urothelial Carcinoma
Interventions: DRUG: Avelumab|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Intervention to Enhance Treatment Engagement and Viral Suppression Among Sexual and Gender Minority Youth in Nigeria
Status: NOT_YET_RECRUITING
Conditions: HIV
Interventions: BEHAVIORAL: Combination Peer navigation and mHealth intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pharmacokinetic (PK) Study in Japanese Non-epileptic Renal Impaired Patients
Status: COMPLETED
Conditions: Healthy Subjects|Renal Impairments
Interventions: DRUG: Levetiracetam 250 mg|DRUG: Levetiracetam 500 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Extraperitoneal SINgle-port rObotic-assisted Radical Prostatectomy (RARP) Versus Transperitoneal Multi-port RARP in the Treatment Of Prostate Cancer (SINO-TOP)
Status: RECRUITING
Conditions: Prostate Adenocarcinoma|Localized Prostate Carcinoma
Interventions: PROCEDURE: Single-port extraperitoneal robotic-assisted radical prostatectomy with Vattikuti Institute Prostatectomy（VIP） techniques|PROCEDURE: Multi-port transperitoneal robotic-assisted radical prostatectomy with bilateral intrafascial nerve-sparing techniques
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transpulmonary Pressure and Airway Pressure Release Ventilation (APRV).
Status: COMPLETED
Conditions: Patient Mechanically Ventilated With APRV Mode
Interventions: OTHER: evaluate the variations of transpulmonary pressure during the use of APRV by clinicians.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Investigation on Safety, Tolerability and Pharmacokinetics of Multiple Doses of NNC0113-0987 in an Oral Formulation in Healthy Subjects
Status: COMPLETED
Conditions: Diabetes|Healthy
Interventions: DRUG: NNC0113-0987|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intensive Vasodilator Therapy in Patients With Essential Hypertension
Status: COMPLETED
Conditions: Essential Hypertension|High Blood Pressure
Interventions: DRUG: Amlodipine|DRUG: Ramipril|DRUG: Lercanidipine|DRUG: Losartan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Unique Effects of Perimenstrual Estradiol or Progesterone Supplementation on Perimenstrual Suicidality
Status: COMPLETED
Conditions: Suicidal Ideation
Interventions: DRUG: Transdermal Estradiol + Placebo|DRUG: Oral Micronized Progesterone + Placebo|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Ultrasound-guided Dextrose Injection Versus Dextrose With Methylprednisolone in Carpal Tunnel Syndrome
Status: RECRUITING
Conditions: Carpal Tunnel Syndrome
Interventions: DRUG: 5% dextrose injection|DRUG: 5% dextrose injections with methylprednisolone acetate 40 mg/ml
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Ablation Versus antiaRrhythmic Drugs in Persistent Atrial Fibrillation
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: PROCEDURE: Atrial fibrillation ablation|DRUG: Antiarrhythmic drug
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Basal Bolus Versus Human Insulin in Hospitalized Patients With Diabetes in Paraguay
Status: COMPLETED
Conditions: Hyperglycemia|Diabetes
Interventions: DRUG: Basal Bolus (Glargine and Glulisine)|DRUG: Human Insulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Cross Over Study to Assess Efficacy and Safety of BDP/FF and Glycopyrrolate
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Glycopyrrolate|DRUG: Glycopyrrolate|DRUG: Glycopyrrolate|DRUG: Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Autologous Bone Marrow Mesenchymal Stem Cells Transplantation for Articular Cartilage Defects Repair
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: PROCEDURE: Bone marrow aspiration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Aspirin in Stroke Patients With Glucose-6-phosphate Dehydrogenase Deficiency (SAST)
Status: RECRUITING
Conditions: G6PD Deficiency|Stroke
Interventions: DRUG: Aspirin|DRUG: Clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Oncoplastic Breast-conserving Surgery in Non-metastatic Breast Cancer Patients
Status: WITHDRAWN
Conditions: Local Recurrence of Malignant Tumor of Breast
Interventions: PROCEDURE: Breast surgery|DRUG: Chemotherapy or endocrine therapy or Trastuzumab therapy|RADIATION: Radiation therapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Trial Evaluating the Efficacy and Safety of HLD200 in Children With ADHD
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: DRUG: HLD200|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of QBECO Versus Placebo in the Treatment of Colorectal Cancer That Has Spread to the Liver
Status: RECRUITING
Conditions: Colorectal Cancer|Liver Metastases
Interventions: DRUG: QBECO|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of S(+)-Ketamine Administered as a Continuous Infusion for the Control of Postoperative Pain
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: S(+)-Ketamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Dipeptidyl Peptidase-4 Inhibitor (DPP4i) for the Control of Hyperglycemia in Patients With COVID-19
Status: COMPLETED
Conditions: Hyperglycemia|Covid19
Interventions: DRUG: Linagliptin tablet|DRUG: Insulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: TY-9591 in the Patients With EGFR Mutations in Advanced NSCLC With Brain Metastases
Status: RECRUITING
Conditions: NSCLC|EGFR Activating Mutation|Brain Metastases
Interventions: DRUG: TY-9591|DRUG: Osimertinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mechanism of Action Study for Psoriasis
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: Methotrexate|DRUG: Adalimumab (Humira)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Evaluate the Safety and Efficacy of MEDI8897 for the Prevention of Medically Attended Lower Respiratory Tract Infection Due to Respiratory Syncytial Virus in Healthy Late Preterm and Term Infants (MELODY)
Status: COMPLETED
Conditions: Respiratory Syncytial Virus Infections
Interventions: DRUG: MEDI8897|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Totally Percutaneous Approach to Endovascular Treatment of Aortic Aneurysms (PEVAR-PRO)
Status: COMPLETED
Conditions: Aneurysm|Aneurysm Abdominal|Aneurysm Thoracic|Aneurysm, Thoracoabdominal Aortic
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Home Blood Pressure Monitoring Before and After COVID-19 Vaccination in Patients at High Risk of Cardiovascular Disease
Status: UNKNOWN
Conditions: Pain|Fatigue|Headache|Myalgia|Chills|Arthralgia|Fever
Interventions: OTHER: heart rate、arrhythmia、blood pressure、central body temperature (ear temperature) and blood oxygen saturation level.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Esmolol Infusion During Laminectomy: Effect on Quality of Recovery
Status: TERMINATED
Conditions: Laminectomy
Interventions: DRUG: Esmolol|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose:
Clinical trial: Personalized Inhibitory Control Training for Compulsive Behavior Change
Status: UNKNOWN
Conditions: OCD
Interventions: BEHAVIORAL: P-CIT protocol|BEHAVIORAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Pulsed Signal Therapy in Patella Chondromalacia
Status: COMPLETED
Conditions: Patella Chondromalacia
Interventions: DEVICE: PST - Pulsed Signal Therapy|DEVICE: Placebo - Sham PST
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Continuous Non-invasive Electrophysiological Monitoring in High Risk Pregnancies
Status: RECRUITING
Conditions: Perinatal Outcomes|Preterm Birth|High Risk Pregnancy
Interventions: DEVICE: continuous eCTG monitoring using the NFMS
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC