pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Combined Use of a Medical Device and a Dietary Complement in Patient Urinary pH Control in Patients With an Implanted Double J Stent.
Status: COMPLETED
Conditions: Stent Complications
Interventions: COMBINATION_PRODUCT: Lit control pHDown
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Rosuvastatin for Reduction of Myocardial Damage and Systemic Inflammation During Coronary Angioplasty
Status: TERMINATED
Conditions: Stable Coronary Artery Disease Undergoing PCI
Interventions: DRUG: Atorvastatin|DRUG: Rosuvastatin|DRUG: Rosuvastatin|DRUG: Ezetimibe|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Safety and Clinical Activity of Immunotherapy Plus Chemotherapy in Metastatic Melanoma Patients
Status: TERMINATED
Conditions: Melanoma
Interventions: BIOLOGICAL: Immunotherapeutic GSK2132231A|DRUG: Dacarbazine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Safety and Clinical Activity of Belantamab Mafodotin in Combination With Daratumumab, Pomalidomide and Dexamethasone in Patients With Relapsed/ Refractory Multiple Myeloma Previously Treated With One Line Therapy Who Are Lenalidomide Refractory
Status: NOT_YET_RECRUITING
Conditions: Multiple Myeloma|Multiple Myeloma in Relapse|Neoplasms|Gammopathy, Monoclonal|Paraproteinemias|Blood Protein Disorders|Haematologic Disease|Corneal Disease|Neoplasms, Plasma Cell
Interventions: DRUG: Belantamab Mafodotin-Blmf|DRUG: Daratumumab|DRUG: Pomalidomide|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Therapy With Biofeedback, Loperamide and Stool Bulking Agents
Status: COMPLETED
Conditions: Fecal Incontinence
Interventions: BEHAVIORAL: Biofeedback|DRUG: Loperamide|DRUG: Stool bulking agent (stericulia or isphagula husk)|OTHER: Combination of biofeedback and medical treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Ibuprofen Versus Acetaminophen vs Their Combination in the Relief of Musculoskeletal Pain in the Emergency Setting
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Ibuprofen|DRUG: Acetaminophen|DRUG: Ibuprofen-acetaminophen combination
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Post Intravenous tPA Monitoring in Ischemic Stroke
Status: COMPLETED
Conditions: Stroke|Ischemic Stroke
Interventions: OTHER: "Hopkins" post tPA for ischemic stroke monitoring protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Paclitaxel, Carboplatin and Gemcitabine in the Treatment of Patients With Advanced Transitional Cell Cancer of the Bladder
Status: COMPLETED
Conditions: Bladder Cancer
Interventions: DRUG: Paclitaxel|DRUG: Carboplatin|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Childhood Asthma Management Program (CAMP) Phases I (Trial), II (CAMPCS), III (CAMPCS/2), and IV (CAMPCS/3)
Status: COMPLETED
Conditions: Asthma|Lung Diseases
Interventions: DRUG: Placebo|DRUG: Nedocromil|DRUG: Budesonide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Carotid Ultrasound to Identify Head and Neck Cancer Survivors With High Cardiovascular Risk After Radiation Therapy
Status: RECRUITING
Conditions: Head and Neck Cancer|Carotid Artery Stenosis|Cardiovascular Complication
Interventions: PROCEDURE: Carotid ultrasound|OTHER: Blood draw|OTHER: Survey
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Diquafosol Tetrasodium Ophthalmic Solution in Subjects With Dry Eye Disease
Status: COMPLETED
Conditions: Dry Eye Disease
Interventions: DRUG: diquafosol tetrasodium ophthalmic solution, 2%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: T-Scan Study of Occlusion in Case of Implant Retained Overdenture
Status: COMPLETED
Conditions: Dental Occlusion, Traumatic|Edentulous Alveolar Ridge
Interventions: PROCEDURE: Monoplane Occlusion|PROCEDURE: Lingualized occlusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare Pharmacokinetics (PK) and Pharmacodynamics (PD) of SAR341402 to Insulin Aspart in Subjects With Type 1 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: DRUG: SAR341402|DRUG: Insulin Aspart|DRUG: Insulin Aspart
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Collection of Autologous Blood Products by Double Erythrocytapheresis
Status: COMPLETED
Conditions: Pre Operative Autologous Donation
Interventions: PROCEDURE: eythrocytapheresis|PROCEDURE: whole blood collection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Laparoscopic Inguinal Hernia Repair- Transabdominal Preperitoneal (TAPP) Versus Totally Extra Peritoneal (TEP)
Status: UNKNOWN
Conditions: Laparoscopic Inguinal Hernia Repair
Interventions: PROCEDURE: Laparoscopic Inguinal Hernia Repair|PROCEDURE: Laparoscopic Inguinal Hernia Repair
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Established Status Epilepticus Treatment Trial
Status: COMPLETED
Conditions: Benzodiazepine Refractory Status Epilepticus
Interventions: DRUG: Fosphenytoin|DRUG: Levetiracetam|DRUG: Valproic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Intra-articular Injection on Temporomandibular Joint Dysfunction
Status: WITHDRAWN
Conditions: Temporomandibular Joint Dysfunction
Interventions: BEHAVIORAL: Routine rehabilitation treatment|PROCEDURE: Intra-articular Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing Abelacimab to Dalteparin in the Treatment of Gastrointestinal/Genitourinary Cancer and Associated VTE
Status: RECRUITING
Conditions: Venous Thromboembolism|Deep Venous Thrombosis|Pulmonary Embolism
Interventions: BIOLOGICAL: Abelacimab|DRUG: Dalteparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Video-Supported Medication Education for Women Undergoing In Vitro Fertilization (IVF): Quality of Life and Psychosocial Effects
Status: RECRUITING
Conditions: Infertility, Female|In Vitro Fertilization|Psychosocial Support Systems|Quality of Life|Health Education
Interventions: OTHER: Education via video (QR code links)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Airway Segmented Stent Modified With 3D Printing for Malignant Stricture Involving Carina and Distal Bronchi
Status: UNKNOWN
Conditions: Stricture; Trachea|Malignant Neoplasm
Interventions: PROCEDURE: Airway stent implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Two Types of Injected Nutritional Supplements in Patients With AIDS and Pneumocystis Carinii Pneumonia (PCP)
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Fat Emulsion 2%|DRUG: Fat Emulsion 20%
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Phase II Study of DCVAC/PCa Added to Standard Chemotherapy for Men With Metastatic Castration Resistant Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer|Prostate Cancer Metastatic
Interventions: BIOLOGICAL: Dendritic Cells DCVAC/PCa|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tap Block vs Conventional Pain Medication for Patients Undergoing Robotic Sacrocolpopexy
Status: UNKNOWN
Conditions: Anesthesia, Local|Prolapse|Prolapse; Female|Prolapse, Vaginal|Prolapse; Vagina, Posthysterectomy|Pain, Postoperative
Interventions: PROCEDURE: TAP block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Breaking up Sitting Time on Cardiometabolic Risk Markers and Cardiac Function Post Myocardial Infarction
Status: RECRUITING
Conditions: Cardiovascular Diseases
Interventions: BEHAVIORAL: Prolonged sitting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Botulinum Toxin Type A (BOTOX®) Treatment of Masseter Muscle Hypertrophy
Status: COMPLETED
Conditions: Masseter Muscle Hypertrophy
Interventions: BIOLOGICAL: botulinum toxin Type A|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: National Retrospective Study of Duodenal Trauma
Status: RECRUITING
Conditions: Duodenal Diverticulization|Pyloric Exclusion|Gastrojejunostomy|Retrograde Duodenostomy|Distal Feeding Tube|Resection and Whipple Procedures|Primary Repairs
Interventions: OTHER: Observational
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Using Web-based Technology to Expand and Enhance Applied Behavioral Analysis Programs for Children With Autism in Military Families
Status: UNKNOWN
Conditions: Autism Spectrum Disorders
Interventions: BEHAVIORAL: Technology-Enhanced Parent Training|BEHAVIORAL: Technology-Enhanced Tutor Training|BEHAVIORAL: Technology-enhanced Early Intensive Behavioral Intervention|BEHAVIORAL: No-Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Near-Infrared Spectroscopy and Cranial Doppler in Premature Newborns With Anemia
Status: UNKNOWN
Conditions: Anemia of Prematurity
Interventions: DEVICE: Cranial Doppler Ultrasonography|DEVICE: Near-Infrared Spectroscopy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Multi-center, Randomized, Blinded Evaluator, Active Control, Parallel, Phase III Study to Evaluate the Efficacy and Safety of TJO-002 in POAG or Ocular Hypertension Patients
Status: COMPLETED
Conditions: Primary Open-angle Glaucoma|Ocular Hypertension
Interventions: DRUG: TJO-002|DRUG: Latanoprost
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Leflunomide+Vemurafenib in V600 Mutant Met. Melanoma
Status: TERMINATED
Conditions: Melanoma
Interventions: DRUG: Vemurafenib|DRUG: Leflunomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Single Dose Study of E6011 in Japanese Healthy Adult Male Subjects (Study E6011-J081-001)
Status: COMPLETED
Conditions: Healthy Male Volunteers
Interventions: DRUG: E6011|DRUG: E6011 Matching Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Individualized Duration of Peg-interferon/Ribavirin Treatment of Hepatitis C
Status: COMPLETED
Conditions: Chronic Hepatitis C, Genotype 1
Interventions: DRUG: Peg-interferon-alfa2a (Pegasys)|DRUG: Ribavirin (Copegus)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anagrelide Retard vs. Placebo: Efficacy and Safety in "At-risk" Patients With Essential Thrombocythaemia
Status: COMPLETED
Conditions: Essential Thrombocythaemia
Interventions: DRUG: Anagrelide retard|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Belzutifan/MK-6482 for the Treatment of Advanced Pheochromocytoma/Paraganglioma (PPGL), Pancreatic Neuroendocrine Tumor (pNET), Von Hippel-Lindau (VHL) Disease-Associated Tumors, Advanced Gastrointestinal Stromal Tumor (wt GIST), or Solid Tumors With HIF-2α Related Genetic Alterations (MK-6482-015)
Status: RECRUITING
Conditions: Pheochromocytoma/Paraganglioma|Pancreatic Neuroendocrine Tumor|Von Hippel-Lindau Disease|Advanced Gastrointestinal Stromal Tumor|HIF-2α Mutated Cancers
Interventions: DRUG: Belzutifan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of CD19 and CD22 Targeted CAR-T Therapy for Relapsed/Refractory B Cell Leukemia and Lymphoma
Status: RECRUITING
Conditions: Leukemia, B-cell|Lymphoma, B-Cell
Interventions: BIOLOGICAL: CD19 and CD22 targeted CAR-T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects and Safety of Caspofungin and Corticosteroids in Pneumocystis Pneumonia in Non-HIV Patients
Status: UNKNOWN
Conditions: Pneumocystis Pneumonia
Interventions: DRUG: caspofungin|DRUG: corticosteroids|DRUG: Sulfanilamides
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Mankai on Glycemic Control Among Patients With T2D
Status: ACTIVE_NOT_RECRUITING
Conditions: Diabetes Mellitus, Type 2
Interventions: DIETARY_SUPPLEMENT: Mankai supplementation|OTHER: Water consumption
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Blood Flow Restricted Resistance Training in Peripheral Arterial Disease
Status: COMPLETED
Conditions: Peripheral Arterial Disease
Interventions: OTHER: Blood flow restricted resistance exercise (BFR)|OTHER: Resistance exercise without blood flow restricted (NON-BFR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Explore the Antiviral Activity, Clinical Outcomes, Safety, Tolerability, and Pharmacokinetics of JNJ-53718678 at Two Dose Levels in Non-Hospitalized Adult Participants Infected With Respiratory Syncytial Virus
Status: COMPLETED
Conditions: Respiratory Syncytial Virus Infections
Interventions: DRUG: JNJ-53718678 500 mg|DRUG: JNJ-53718678 80 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Multiparametric Magnetic Resonance Imaging of the Prostate to Assess Disease Progression and Genomics in Patients Undergoing Active Surveillance for Prostate Cancer
Status: RECRUITING
Conditions: Prostate Cancer
Interventions: DIAGNOSTIC_TEST: mpMRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study of Chemoradiation Plus Pembrolizumab for Locally Advanced Laryngeal Squamous Cell Carcinoma
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: DRUG: Pembrolizumab|RADIATION: Radiation Therapy|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioprosthetic Mesh to Expand the Lower Pole in Tissue Expander Reconstruction
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DEVICE: Alloderm|DEVICE: Surgimend
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Does Montelukast Decrease Post Adenotonsillectomy Pain in Children
Status: ACTIVE_NOT_RECRUITING
Conditions: Pain
Interventions: DRUG: Montelukast|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Real-World Study of Magnetic Resonance-guided Laser Interstitial Thermal Therapy for Drug-resistant Epilepsy
Status: ENROLLING_BY_INVITATION
Conditions: Drug Resistant Epilepsy
Interventions: DEVICE: Magnetic Resonance-guided Laser Interstitial Thermal Therapy (MRgLITT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Accelerated iTBS in Smoking Cessation
Status: COMPLETED
Conditions: Nicotine Dependence|Smoking Cessation
Interventions: DEVICE: Active intermittent theta burst stimulation|DEVICE: Sham intermittent theta burst stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Replacing Invasive Cystoscopy With Urine Testing for Non-muscle Invasive Bladder Cancer Surveillance
Status: RECRUITING
Conditions: Non-muscle-invasive Bladder Cancer
Interventions: PROCEDURE: Cystoscopy|DIAGNOSTIC_TEST: Bladder EpiCheck urine test|DIAGNOSTIC_TEST: Xpert Bladder Cancer Monitor urine test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study of Cadonilimab Combined With AK112 as Second-line Therapy in Patients With Advanced Hepatocellular Carcinoma
Status: NOT_YET_RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: BIOLOGICAL: AK104+AK112
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Observation or Radiation Therapy With or Without Combination Chemotherapy in Treating Patients With Low-Grade Glioma
Status: COMPLETED
Conditions: Brain and Central Nervous System Tumors
Interventions: DRUG: lomustine|DRUG: procarbazine hydrochloride|DRUG: vincristine sulfate|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Opium Tincture (OT) With Methadone for Medication-assisted Treatment of Opioid Use Disorder
Status: COMPLETED
Conditions: Opioid Dependence
Interventions: DRUG: opium|DRUG: methadone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Safety and Effects of Intravenous (IV) Conivaptan on the Hepatic Hemodynamic Response in Cirrhotic Patients
Status: COMPLETED
Conditions: Liver Cirrhosis
Interventions: DRUG: conivaptan|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of ICP-192 in Patients With Advanced Solid Tumors
Status: RECRUITING
Conditions: Advanced Solid Tumors|Urothelial Carcinoma|Cholangiocarcinoma
Interventions: DRUG: Drug ICP-192
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: First Line Therapy of Advanced Stage Follicular Lymphoma in Patients < 60 Years Not Eligible fo Standard Immunochemotherapy and in All Patients ≥ 60 Years
Status: COMPLETED
Conditions: Indolent Non-hodgkin Lymphoma
Interventions: DRUG: Obinutuzumab|DRUG: Bendamustine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intra-operative Assessment of the Intellirod LOADPRO Spinal Rod Strain Sensor for Use During Kyphotic Corrective Surgery
Status: UNKNOWN
Conditions: Kyphosis|Spinal Fractures
Interventions: DEVICE: LOADPRO
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Malabsorption Blood Test:Toward a Novel Approach to Quantify Steatorrhea
Status: COMPLETED
Conditions: Cystic Fibrosis|Pancreatic Insufficiency
Interventions: OTHER: Pentadecanoic acid (PA) and Triheptadecanoin (THA)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: An Efficacy, Safety, and Pharmacokinetics Study of Subcutaneously Administered Ustekinumab in the Treatment of Moderate to Severe Chronic Plaque Psoriasis in Pediatric Participants Greater Than or Equal to 6 to Less Than 12 Years of Age
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: Ustekinumab 0.75 mg/kg|DRUG: Ustekinumab 45 mg|DRUG: Ustekinumab 90 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Interactions Between HIV Protease Inhibitors and Calcium Channel Blockers
Status: COMPLETED
Conditions: HIV Infections|Cardiovascular Diseases|Hypertension
Interventions: DRUG: Indinavir sulfate|DRUG: Ritonavir|DRUG: Amlodipine|DRUG: Diltiazem HCl
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Growth Hormone or Sildenafil as Therapies for Fatigue in Mild- Traumatic-brain-injury (MTBI)
Status: COMPLETED
Conditions: Traumatic Brain Injury
Interventions: DRUG: Growth Hormone|DRUG: Sildenafil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effect of Guided Imagery and Music Therapy on Post-Operative Recovery After Gynecological Oncology Surgery
Status: TERMINATED
Conditions: Ovarian Cancer|Uterine Cancer
Interventions: BEHAVIORAL: Guided imagery and music therapy|BEHAVIORAL: White Noise|OTHER: No intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Efficacy of the Use of Botox on Acne
Status: TERMINATED
Conditions: Acne Vulgaris
Interventions: DRUG: Botulinum Neurotoxin Type A|DRUG: Bacteriostatic saline
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Get Going After concussIonN Lite
Status: RECRUITING
Conditions: Brain Concussion|Mild Traumatic Brain Injury|Commotio Cerebri
Interventions: BEHAVIORAL: Enhanced usual care (EUC)|BEHAVIORAL: Get Going after concussIoN Lite
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Stepped Care aiTBS 2 Depression Study (Ghent)
Status: COMPLETED
Conditions: Depressive Disorder, Major|Treatment Resistant Depression|Melancholia
Interventions: DEVICE: aiTBS|BEHAVIORAL: CCT|DRUG: SSRI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dose Escalation, Double-Blind Treatment With Duloxetine Hydrochloride Once Daily Dosing for Evaluation of Safety in Major Depression
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: Duloxetine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: THE EFFECT OF ARGININE AND GLUTAMINE ON COVID-19 PATIENTS OUTCOME: A RANDOMIZED CLINICAL TRIAL
Status: COMPLETED
Conditions: COVID-19
Interventions: DIETARY_SUPPLEMENT: Neomune
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Herpes Labialis by Photodynamic Therapy
Status: COMPLETED
Conditions: Photodynamic Therapy|Herpes Simplex, Labial
Interventions: DEVICE: photodynamic therapy herpes labialis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Inhaled Sevoflurane Compared to Intravenous Sedation Post Coronary Artery Bypass Grafting
Status: COMPLETED
Conditions: Myocardial Reperfusion Injury|Atrial Fibrillation
Interventions: DRUG: Sevoflurane|DRUG: propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Different Endoscopic Radial Artery Harvesting Devices
Status: COMPLETED
Conditions: CABG Graft Integrity
Interventions: DEVICE: LigaSure endoscopic vessel harvesting|DEVICE: TLS2 endoscopic vessel harvesting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Yellow 577 nm Laser Versus Green 532 nm Laser for Proliferative Diabetic Retinopathy
Status: UNKNOWN
Conditions: Proliferative Diabetic Retinopathy
Interventions: PROCEDURE: Pan retinal photocoagulation laser treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Amrubicin Chemotherapy as First Line in Metastatic or Unresectable Soft Tissue Sarcoma
Status: COMPLETED
Conditions: Soft Tissue Sarcoma
Interventions: DRUG: Amrubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Metformin in Patients With Mild Graves' Ophthalmopathy
Status: UNKNOWN
Conditions: Mild Graves' Ophthalmopathy
Interventions: DRUG: Metformin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Practical Application of Accelerated iTBS for MDD
Status: COMPLETED
Conditions: Major Depressive Disorder|Major Depressive Disorder, Recurrent Episode, Severe|Major Depressive Disorder, Recurrent, Moderate
Interventions: DEVICE: NeuroStar TMS
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Dry Needling and Physical Therapy Versus Physical Therapy Alone Following Shoulder Stabilization Repair
Status: COMPLETED
Conditions: Shoulder Pain
Interventions: DEVICE: Rehabilitation and Dry Needling|DEVICE: Rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Binimetinib and Encorafenib in Advanced BRAF Mutant Cancers
Status: COMPLETED
Conditions: Advanced BRAF Mutant Cancers
Interventions: DRUG: Binimetinib|DRUG: Encorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigation of the Effect of Food on the Bioavailability of a 25 mg Empagliflozin Tablet as Well as Assessment of Dose Proportionality Between 10 mg and 25 mg Empagliflozin Tablets Under Fasting Conditions.
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Empagliflozin|DRUG: Empagliflozin|DRUG: Empagliflozin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Neurodynamics Nerve Flossing on Femoral Neuropathy in Haemophilic Patients
Status: COMPLETED
Conditions: Femoral Neuropathy in Haemophilic Patients
Interventions: OTHER: Neurodynamics Nerve flossing|OTHER: conventional selected exercise program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Cranberry Consumption in Vascular Function in Healthy Individuals
Status: COMPLETED
Conditions: Healthy Men
Interventions: DIETARY_SUPPLEMENT: Cranberry 320|DIETARY_SUPPLEMENT: Cranberry 640|DIETARY_SUPPLEMENT: Cranberry 960|DIETARY_SUPPLEMENT: Cranberry 1280|DIETARY_SUPPLEMENT: Cranberry 1600|DIETARY_SUPPLEMENT: Cranberry deprived supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Superselective Adrenal Arterial Embolization for Bilateral Idiopathic Hyperaldosteronism: A Prospective Cohort Study
Status: UNKNOWN
Conditions: Primary Aldosteronism Due to Adrenal Hyperplasia (Bilateral)
Interventions: PROCEDURE: superselective adrenal arterial embolization
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Photobiomodulation for the Treatment of Diabetic Macular Edema
Status: COMPLETED
Conditions: Diabetic Retinopathy
Interventions: DEVICE: 670nm PBM|DRUG: intravitreous VEGF-inhibitors
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hypofractionated 3-Dimensional Radiation Therapy in Treating Patients With Newly Diagnosed Stage I, Stage II, or Stage III Non-Small Cell Lung Cancer. ICORG 99-09
Status: COMPLETED
Conditions: Lung Cancer
Interventions: RADIATION: hypofractionated radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: n-3 Polysaturated Fatty Acids-rich Diet in Psoriasis
Status: COMPLETED
Conditions: Plaque-type Psoriasis|Obesity (Body Mass Index >30 kg/m2)
Interventions: DIETARY_SUPPLEMENT: Energy-restricted, n-3 polysaturated fatty acids-rich diet|DIETARY_SUPPLEMENT: Usual diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ThromboAblation in Acute Myocardial Infarction
Status: TERMINATED
Conditions: ST Elevation Acute Myocardial Infarction
Interventions: DEVICE: Laser Thromboablation|DEVICE: PTCA (Direct Stenting)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Success of Short Dental Implants Alone and Standard Dental Implants Combined With Osteotome Sinus Floor Elevation in Posterior Maxillae
Status: COMPLETED
Conditions: Jaw, Edentulous, Partially
Interventions: PROCEDURE: Dental implants installation|DEVICE: Osteotome Sinus floor elevation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of CBT and tDCS on Fibromyalgia Patients
Status: COMPLETED
Conditions: Fibromyalgia|Chronic Pain
Interventions: DEVICE: Transcranial Direct Current Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Psychoactive Substances in Newborns' Hair Whose Mothers Were Treated and Followed at the Nice University Hospital - New Born Hair Study
Status: UNKNOWN
Conditions: Newborn
Interventions: PROCEDURE: Umbilical cord blood and hair collection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Ketohexokinase Inhibition in NAFLD
Status: COMPLETED
Conditions: NAFLD
Interventions: DRUG: Ketohexokinase inhibition|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Stereotactic Radiation Therapy and Sorafenib in the Treatment of Hepatocellular Carcinoma
Status: TERMINATED
Conditions: Hepatocellular Carcinoma|Liver Cancer
Interventions: DRUG: Sorafenib|RADIATION: Stereotactic Body Radiotherapy (SBRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Features of KN069 in Participants With Obesity or Overweight
Status: RECRUITING
Conditions: Overweight or Obesity
Interventions: DRUG: KN069
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Guided Treatment Based on Mini-PDX in Metastatic Triple Negative Breast Cancer
Status: UNKNOWN
Conditions: Triple Negative Breast Cancer
Interventions: DRUG: Personalized treatment guided by mini-PDX and RNA sequencing|DRUG: Nab paclitaxel|DRUG: Eribulin|DRUG: Vinorelbine|DRUG: Gemcitabine|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility of Delivering VergeRx at FQHCs
Status: NOT_YET_RECRUITING
Conditions: Tobacco Use Cessation
Interventions: BEHAVIORAL: QuitAid|BEHAVIORAL: SmokefreeTXT|DRUG: Nicotine Replacement Therapy Patch|DRUG: Nicotine lozenge
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Cricoid Pressure During Videolaryngoscopy Versus Direct Laryngoscopy
Status: NOT_YET_RECRUITING
Conditions: Cricoid Pressure
Interventions: OTHER: Intubation device order
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Repeatability of Electroretinogram and Visual Evoked Potential
Status: UNKNOWN
Conditions: Retinal Disease|Visual Impairment|Vision Disorders
Interventions: DIAGNOSTIC_TEST: Electroretinogram (ERG)|DIAGNOSTIC_TEST: Visual evoked potential (VEP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparison of Two Types of Videolaryngoscope and Direct Laryngoscope in Expected Non-difficult Airway Patients
Status: UNKNOWN
Conditions: Laryngoscopes
Interventions: DEVICE: The laryngoscope used for tracheal intubation under general anesthesia for patients with expected non-difficult airway conditions.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: NKTR-102 Versus Irinotecan in Patients With Second-Line, Irinotecan-Naïve, KRAS Mutant, Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: NKTR-102|DRUG: irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study to Compare Dolutegravir 50mg Film-coated Tablets
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Dolutegravir 50 MG Film Coated Tablet|DRUG: Tivicay 50mg, film-coated tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Tislelizumab (One Anti-PD-1 Antibody) Plus Low-dose Bevacizumab for Bevacizumab Refractory Recurrent Glioblastoma
Status: NOT_YET_RECRUITING
Conditions: Recurrent Glioblastoma
Interventions: DRUG: Tislelizumab plus Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Listening Effort in Cochlear Implant Users
Status: RECRUITING
Conditions: Auditory Perception; Abnormal|Hearing Loss, Sensorineural|Hearing Loss
Interventions: BEHAVIORAL: sentence manipulations
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of Silicone-covered Metallic Ureteral Stent and Double-J Stent for Malignant Ureteral Obstruction
Status: UNKNOWN
Conditions: Malignant Ureteral Obstruction
Interventions: DEVICE: Silicone-covered metallic stent|DEVICE: Double-J stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Modified Mirror Therapy in Patients With Upper Limb Hemiparesis After Stroke
Status: TERMINATED
Conditions: Stroke
Interventions: BEHAVIORAL: Routine treatment|BEHAVIORAL: Rehabilitation training|BEHAVIORAL: Modified mirror therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bioavailability of Intranasal Dexmedetomidine
Status: COMPLETED
Conditions: Pharmacokinetics|Arthritis Knee|Arthritis of Hip|Anesthesia
Interventions: DEVICE: Dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Post-surgical Chronic Pain After Retroperitoneal Laparoscopic Living Kidney Donor
Status: COMPLETED
Conditions: Chronic Post Operative Pain|Kidney Transplant; Complications|Anesthesia Regional|Laparoscopy
Interventions: PROCEDURE: Quadratus lumborum (QL) block|PROCEDURE: Erector Spinae Plane (ESP) Block
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical Evaluation of Placement of Radiofrequency-based Plasma Microdebridement in the Treatment Algorithm for Foot and Ankle Tendinosis and Plantar Fasciosis
Status: WITHDRAWN
Conditions: Plantar Fasciosis, Achilles Tendinosis
Interventions: DEVICE: TOPAZ MicroDebrider
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Zemplar® Capsule in Reducing Serum Intact Parathyroid Hormone Levels in Chronic Kidney Disease Stage 5 Subjects on Hemodialysis or Peritoneal Dialysis
Status: COMPLETED
Conditions: Kidney Disease
Interventions: DRUG: Zemplar Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Algorithm to Control Postprandial, Post Exercise and Night Glucose Excursions in a Portable Closed Loop Format
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: DEVICE: Artificial Pancreas (Inreda Diabetic BV)|DEVICE: Insulin pump therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Perinatal Arterial Stroke: A Multi-site RCT of Intensive Infant Rehabilitation (I-ACQUIRE)
Status: RECRUITING
Conditions: Perinatal Stroke|Hemiparesis
Interventions: BEHAVIORAL: I-ACQUIRE - High Dosage|BEHAVIORAL: I-ACQUIRE - Moderate Dosage|BEHAVIORAL: Usual & Customary Treatment (U&CT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dose Escalation Study of the Pharmacodynamics, Pharmacokinetics, Safety, and Immunogenicity of BCD-132 in Patients With Relapsing-Remitting Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: BIOLOGICAL: BCD-132
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Differential Effects of Milk Proteins on Postprandial Lipemia in Response to a Fat-Rich Meal in Type 2 Diabetes
Status: COMPLETED
Conditions: Postprandial Lipemia|Type 2 Diabetes
Interventions: DIETARY_SUPPLEMENT: Casein|DIETARY_SUPPLEMENT: Whey Isolate|DIETARY_SUPPLEMENT: Whey Hydrolysate|DIETARY_SUPPLEMENT: Alphalact-Albumin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Exploring the MEchanism of Plaque Rupture in Acute Coronary Syndrome Using Coronary CT Angiography and computationaL Fluid Dynamic
Status: UNKNOWN
Conditions: Acute Coronary Syndrome|Myocardial Infarction|Plaque, Atherosclerotic|Rupture, Spontaneous
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Analgesic Efficacy Between of Interscalene Block With Liposomal Bupivacaine With Bupivacaine and Dexamethasone
Status: COMPLETED
Conditions: Total Shoulder Arthroplasty|Shoulder Osteoarthritis
Interventions: DEVICE: Interscalene catheter|DRUG: Liposomal bupivacaine|DRUG: Dexamethasone|DRUG: Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Cranioplasty Using Native Bone Autograft Versus Synthetic Bone Allograft
Status: UNKNOWN
Conditions: Surgical Procedure, Unspecified
Interventions: DEVICE: Synthetic Bone Allograft (ClearFit)|OTHER: Autograft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lumbar Plexus Catheter Versus Femoral Nerve Catheter for Postoperative Pain After Anterior Cruciate Ligament (ACL) Repair
Status: UNKNOWN
Conditions: Postoperative Pain
Interventions: PROCEDURE: lumbar plexus catheter|PROCEDURE: femoral nerve catheter|PROCEDURE: single-shot femoral block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Gastric Slow Wave and Autonomic Nervous Function in Cirrhotic Patients With Esophageal Varices After Ligation-A Clinical Research
Status: COMPLETED
Conditions: Esophageal Varices in Cirrhosis of the Liver
Interventions: DIAGNOSTIC_TEST: Electrogastrogram(EGG)|DIAGNOSTIC_TEST: Heart Rate Variability(HRV)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation the Effect of Using Preoperative Ibuprofen Versus Low Level Laser Therapy on Inferior Alveolar Nerve Block
Status: UNKNOWN
Conditions: Postoperative Pain
Interventions: DRUG: Ibuprofen|DEVICE: Diode laser|DEVICE: Nonactive Diode laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Assessment of Osseointegration Properties of Nano-Hydroxy Apatite Coated Titanium Implant
Status: COMPLETED
Conditions: Implant Site Reaction
Interventions: OTHER: nano-hydroxy apatite coated titanium implants|OTHER: sandblasted large acid itched coated titanium implant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Semaglutide for Alcohol Use Disorder
Status: COMPLETED
Conditions: Alcohol Use Disorder|Cigarette Smoking
Interventions: DRUG: Semaglutide|DRUG: Sham/placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Aspirin Mono Therapy 12-months After Drug-eluting Stents Implantation
Status: UNKNOWN
Conditions: Drug-eluting Stent (DES)
Interventions: DRUG: Atorvastatin (High dose statin treatment)|DRUG: Pravastatin (High dose statin treatment)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Music Therapy on High Risk Pregnant Women of Non-Stress Test
Status: COMPLETED
Conditions: Anxiety|Fetal Distress|Music
Interventions: OTHER: Music Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Ultra Curto (Ultra Short) TB Prevention Therapy
Status: COMPLETED
Conditions: Tuberculosis
Interventions: DRUG: Rifapentine 600 mg and INH 300 mg|DRUG: Rifapentine 900 mg and INH 900 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Use of Topical Subgingival Application of Simvastatin Gel in the Treatment of Peri-Implant Mucositis
Status: COMPLETED
Conditions: Peri-implant Mucositis
Interventions: DRUG: Simvastatin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Determine the Effects of Multiple-dose Omeprazole on the Single-dose Pharmacokinetics of Tipranavir (TPV) Coadministered With Ritonavir (RTV) in Healthy Adult Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Tipranavir (TPV)|DRUG: Ritonavir|DRUG: Omeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Two Oral Appliances for Managing Oral Self-biting Injuries in Patients With ALS
Status: UNKNOWN
Conditions: Satisfaction
Interventions: DEVICE: Hard occlusal splint|DEVICE: Flexible customized mouthguard
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Regulation of Intestinal and Hepatic Lipoprotein Production by Glucagon Like Peptide 2
Status: COMPLETED
Conditions: Dyslipidemia
Interventions: DRUG: GLP-2|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE