pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Trial of Anti-TNF Chimeric Monoclonal Antibody (cA2) in Korean Patients With Active Rheumatoid Arthritis Despite Methorexate (Extension Part)(Study P05645)(COMPLETED)
Status: COMPLETED
Conditions: Arthritis, Rheumatoid
Interventions: BIOLOGICAL: Infliximab + methotrexate (MTX)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Brain Small Chain Fatty Acid Metabolism in Bipolar Disorder: Ketones
Status: RECRUITING
Conditions: Bipolar Disorder
Interventions: DIETARY_SUPPLEMENT: Ketone Ester Beverage|BEHAVIORAL: Low Glycemic Index Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Quisinostat, a Histone Deacetylase Inhibitor, in Combination With Chemotherapy
Status: COMPLETED
Conditions: Ovarian Cancer
Interventions: DRUG: Quisinostat|DRUG: Paclitaxel|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Brachiocephalic Arteriovenous Fistulae: Two Different Techniques of Bloodless Surgery and Their Effect on Fistula Stenosis.
Status: TERMINATED
Conditions: Arteriovenous Fistula|Tourniquet|Stenosis
Interventions: OTHER: Tourniquet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Randomized Trial for Mixed Acute Rejection
Status: COMPLETED
Conditions: Graft Rejection
Interventions: DRUG: Rabbit Antithymocyte Globulin (RATG)|DRUG: Rituximab|DRUG: Bortezomib|DRUG: Acetaminophen|DRUG: Antihistamine|DRUG: Methylprednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assesment of Muscular Unloading in Chronic Obstructive Pulmonary Disease (COPD) Patients With NIV
Status: COMPLETED
Conditions: COPD
Interventions: DEVICE: Basal record|DEVICE: PS 10 record|DEVICE: PS 15 record|DEVICE: PS 20 record
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study to Evaluate Efficacy and Safety of HLX10 Combined With Albumin-Bound Paclitaxel in Patients With Advanced Cervical Cancer Who Have Progressive Disease or Intolerable Toxicity After First-Line Standard Chemotherapy
Status: UNKNOWN
Conditions: Cervical Cancer
Interventions: DRUG: HLX10+Albumin-Bound Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Light and Ion Maintenance In Treatment for Depression (LIMIT-D): Feasibility Study
Status: RECRUITING
Conditions: Major Depressive Disorder, Recurrent, in Remission
Interventions: DEVICE: Negative ion therapy|DEVICE: Light therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating the Safety and Effectiveness of the FLEXUS(TM) Interspinous Spacer
Status: TERMINATED
Conditions: Lumbar Spinal Stenosis
Interventions: DEVICE: FLEXUS(TM) Interspinous Spacer|DEVICE: XSTOP® Interspinous Spacer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of Kinesio Taping in Women With Knee Osteoarthritis
Status: COMPLETED
Conditions: Kinesio Taping|Knee Osteoarthritis
Interventions: OTHER: application of kinesio taping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Sitagliptin on Postprandial Lipemia in Men With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus|Postprandial Lipemia
Interventions: DRUG: Sitagliptin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase Ib Trial to Evaluate the Safety and Efficacy of FMT and Nivolumab in Subjects With Metastatic or Inoperable Melanoma, MSI-H, dMMR or NSCLC
Status: UNKNOWN
Conditions: Melanoma Stage IV|Unresectable Melanoma|NSCLC Stage IV
Interventions: BIOLOGICAL: Fecal Microbial Transplantation by capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating Multiple Ascending Doses Of ATN-103 In Japanese Subjects With Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: BIOLOGICAL: ATN-103 10 mg q4wks|BIOLOGICAL: ATN-103 30 mg q4wks|BIOLOGICAL: ATN-103 80 mg q4wks|BIOLOGICAL: ATN-103 10 mg q8wks|BIOLOGICAL: ATN-103 80 mg q8wks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Golazo® Peripheral Atherectomy System for a Safe and Effective Atherectomy (GREAT Trial)
Status: RECRUITING
Conditions: Peripheral Arterial Disease
Interventions: DEVICE: Golazo® Peripheral Atherectomy System (Golazo® Peripheral AS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ATTUNE Revision System in the Revision Total Knee Arthroplasty Population
Status: ACTIVE_NOT_RECRUITING
Conditions: Revision Total Knee Arthroplasty
Interventions: DEVICE: ATTUNE Revision Knee System in Revision Total Knee Arthroplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of the Exoskeleton for Assisting Ambulatory Activities in People With Subacute Stroke
Status: RECRUITING
Conditions: Stroke|Exoskeleton
Interventions: DEVICE: FREE Walk Exoskeleton|OTHER: Traditional Rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Measurement of Hemodynamic Variables Under Spinal Anesthesia With Varied Positioning
Status: COMPLETED
Conditions: Pregnancy|Anesthesia
Interventions: OTHER: Supine position|OTHER: Right lateral position|OTHER: Left lateral position
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Hippocampus Avoidance PCI vs PCI
Status: COMPLETED
Conditions: Small Cell Lung Cancer|Lung Cancer
Interventions: RADIATION: Radiation Prophylactic Cranial Irradiation|RADIATION: Radiation Hippocampal Avoidance PCI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Endoscopic Ultrasound (EUS) Guided-Celiac Plexus Neurolysis (CPN) in Unresectable Pancreatic Cancer
Status: COMPLETED
Conditions: Pain|Pancreatic Cancer
Interventions: PROCEDURE: Ultrasound guided celiac plexus neurolysis (CPN)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose:
Clinical trial: Evaluation of the Effect of Changyou Probiotic Flavored Yogurt on Intestinal Health
Status: COMPLETED
Conditions: Intestinal Health
Interventions: DIETARY_SUPPLEMENT: Bright Changyou probiotic flavored yogurt|DIETARY_SUPPLEMENT: Bright Changyou lactobacillus flavored yogurt|DIETARY_SUPPLEMENT: Bright flavored yogurt
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The G Protein-Coupled Receptor Kinase Type 2 Inhibitor Paroxetine as Adjunctive Therapy to Improve Insulin Sensitivity in Patients With Type 2 Diabetes Mellitus
Status: NOT_YET_RECRUITING
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Paroxetine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: the Effect of Combined Bilateral Infraorbital and Infratrochlear Nerve Block in Nasal Surgeries
Status: NOT_YET_RECRUITING
Conditions: Anesthesia
Interventions: PROCEDURE: combined bilateral infraorbital and infratrochlear nerve blocks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Oral Glucose Stimulation in Normal-weight and Obese Volunteers
Status: COMPLETED
Conditions: Endocrine System Diseases
Interventions: DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: Glucose 25g|DIETARY_SUPPLEMENT: Glucose 10g
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Dialectical Behavior Therapy for Adolescents With Self-harm and Suicidal Behavior- an Open Trial
Status: RECRUITING
Conditions: Self-harm|Suicidal Ideation|Suicide and Self-harm
Interventions: BEHAVIORAL: Dialectical behavior therapy for adolescents (DBT-A)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Oral Nutritional Supplements With Specialized Nutrients on Functional Recovery and Morbidity After Gastrointestinal Surgery
Status: TERMINATED
Conditions: Patients Following Gastrointestinal Surgery
Interventions: DIETARY_SUPPLEMENT: Resource Support®|DIETARY_SUPPLEMENT: Resource Protein®|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: A Study in Healthy Men to Test How Esomeprazole Influences the Amount of BI 1819479 in the Blood
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BI 1819479|DRUG: Esomeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability of Lacosamide in Patients With Gain-of-function Nav1.7 Mutations Related Small Fiber Neuropathy
Status: COMPLETED
Conditions: Small Fiber Neuropathy
Interventions: DRUG: Lacosamide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Efficacy Study of Compound LY2624803 in the Treatment of Patients With Chronic Insomnia
Status: COMPLETED
Conditions: Primary Insomnia|Secondary Insomnia
Interventions: DRUG: LY2624803|DRUG: LY2624803|DRUG: Placebo|DRUG: zolpidem
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Evaluation of Hyperthermic Baths in the Treatment of Seizures in Children With CDKL5 Deficiency
Status: NOT_YET_RECRUITING
Conditions: CDKL5 Deficiency Disorder
Interventions: OTHER: Hyperthermic Baths
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of AI Genetic Counseling Program vs In-person Genetic Counseling in Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer
Interventions: GENETIC: Automated program (ChatBot)|GENETIC: Genetics counselor|OTHER: BCGCKQ Survey|OTHER: Satisfaction Survey|DEVICE: Genetic testing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Lapatinib and Doxorubicin Hydrochloride Liposome in Treating Patients With Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: lapatinib ditosylate|DRUG: Doxil
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tailored ImmunoTherapy Approach With Nivolumab in Subjects With Metastatic or Advanced Transitional Cell Carcinoma
Status: UNKNOWN
Conditions: Transitional Cell Carcinoma|Advanced Cancer|Metastatic Cancer
Interventions: BIOLOGICAL: Nivolumab/Ipilimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PD-1 Combined With Chemotherapy and PULSAR in LAPC and Local Recurrence Patients
Status: RECRUITING
Conditions: Pancreatic Cancer
Interventions: DRUG: PD-1|DRUG: Nab-paclitaxel|DRUG: Gemcitabine|RADIATION: PULSAR
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Volasertib With or Without Azacitidine in Patients With Myelodysplastic Syndromes
Status: TERMINATED
Conditions: Myelodysplastic Syndromes
Interventions: DRUG: Volasertib|DRUG: Volasertib|DRUG: Azacitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rotator Cuff Repair Under Isolated Loco-regional Anesthesia
Status: RECRUITING
Conditions: Shoulder Cuff Surgical Repair
Interventions: PROCEDURE: Arthroscopic rotator cuff repair|DRUG: naropeine or chirocaine (Arthroscopic rotator cuff repair under LRA associated to GA)|DRUG: naropeine or chirocaine (Arthroscopic rotator cuff repair under LRA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Irinotecan, Carboplatin and Radiation Therapy Followed by Bevacizumab in Limited Stage Small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DRUG: Irinotecan|DRUG: Carboplatin|DRUG: Bevacizumab|RADIATION: Radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Polidocanol Foam 3% in the Treatment of II Degree Hemorrhoidal Disease
Status: COMPLETED
Conditions: Second-degree Hemorrhoids
Interventions: DRUG: Polidocanol foam (Atossisclerol® 3%)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Impact of Qigong on Quality of Life and Sleep Disturbance in Head and Neck Patients Undergoing Radiotherapy
Status: UNKNOWN
Conditions: Head and Neck Cancer
Interventions: BEHAVIORAL: Qigong|BEHAVIORAL: Wait-list control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Exploring the Effectiveness the Attitude, Competence of Care, Empathy Among the Home Care Workers With Dementia People
Status: COMPLETED
Conditions: Empathy|Attitude|Competence
Interventions: OTHER: VR films
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Partial Thromboplastin Time During the First 24 Hours of Antithrombotic Prophylaxis Using Unfractionated Heparin (UFH)
Status: COMPLETED
Conditions: Thrombosis
Interventions: DRUG: Variation of heparin dose|DRUG: Variation of heparin dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multicenter Comparison of Fluconazole (UK-49,858) and Amphotericin B as Treatment for Acute Cryptococcal Meningitis
Status: COMPLETED
Conditions: Meningitis, Cryptococcal|HIV Infections
Interventions: DRUG: Flucytosine|DRUG: Fluconazole|DRUG: Amphotericin B
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: The Immediate Effects of Kinesio-Taping on Scapular Muscle Endurance and Strength in Asymptomatic Subjects
Status: COMPLETED
Conditions: Asymptomatic Subjects
Interventions: OTHER: -Scapular endurance test|OTHER: -Muscle strength test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Phase 3 Evaluation of Re-Injection of NX-1207 for the Treatment of Benign Prostatic Hyperplasia (BPH)
Status: COMPLETED
Conditions: Benign Prostatic Hyperplasia
Interventions: DRUG: NX-1207
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non-opioid Based Pain Control After Thyroidectomy
Status: COMPLETED
Conditions: Pain|Thyroidectomy
Interventions: OTHER: Acetaminophen and hydrocodone based pain control|OTHER: Acetaminophen and ibuprofen based pain control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Metabolic Effects of Angiotensin-(1-7)
Status: RECRUITING
Conditions: Obesity|Insulin Resistance|Hypertension|Metabolic Cardiovascular Syndrome
Interventions: DRUG: Angiotensin-(1-7)|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Efficacy of Pioglitazone on Bone Metabolism in Postmenopausal Women With Impaired Fasting Glucose.
Status: COMPLETED
Conditions: Bone Metabolism
Interventions: DRUG: Pioglitazone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Patients' Postpartum Recovery Using ObsQoR-10 Score in Pregnant Women in Vaginal Delivery With and Without Neuraxial Labor Analgesia
Status: RECRUITING
Conditions: Analgesia
Interventions: PROCEDURE: labor with neuraxial labor analgesia|PROCEDURE: labour without noroaxial labor analgesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Low Level Laser Therapy on Prevention of Radiotherapy Induced Xerostomia in Cancer Patients.
Status: UNKNOWN
Conditions: Head and Neck Cancer
Interventions: DEVICE: low level laser|DRUG: citric acid solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Double Dose Magnesium Sulphate in Moderate-severe Asthma in Paediatrics
Status: UNKNOWN
Conditions: Asthma in Children
Interventions: DRUG: Magnesium Sulfate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Naproxen for Acute Pain After Surgery: A Randomized, Placebo-Controlled Trial
Status: UNKNOWN
Conditions: Pain, Postoperative
Interventions: DRUG: naproxen|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: TOTAL: A Multisite RCT
Status: RECRUITING
Conditions: Obesity|Overweight
Interventions: BEHAVIORAL: Teaching Obesity Treatments to Adult Learners (TOTAL)|BEHAVIORAL: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study to Investigate the Safety and Immunogenicity of the Quadrivalent Influenza mRNA Vaccines in Adults Aged 18 Years and Above
Status: ACTIVE_NOT_RECRUITING
Conditions: Influenza Immunization
Interventions: BIOLOGICAL: Quadrivalent Influenza mRNA Vaccine MRT5421|BIOLOGICAL: Quadrivalent Influenza mRNA Vaccine MRT5424|BIOLOGICAL: Quadrivalent Influenza mRNA Vaccine MRT5429|BIOLOGICAL: Quadrivalent Influenza Standard Dose Vaccine|BIOLOGICAL: Quadrivalent Influenza High-Dose Vaccine|BIOLOGICAL: Quadrivalent Recombinant Influenza Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The PRESS RA: Protein and Resistance Exercise Supplementation Study for Rheumatoid Arthritis
Status: TERMINATED
Conditions: Rheumatoid Arthritis
Interventions: DIETARY_SUPPLEMENT: Protein|DIETARY_SUPPLEMENT: Carbohydrate (Placebo)|OTHER: Resistance Exercise Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Stepwise Strategy to Improve CANcer Screening Adherence: Cervical Cancer
Status: COMPLETED
Conditions: Mass Screening|Early Detection of Cancer|Uterine Cervical Neoplasm|Text Message|Reminder Systems
Interventions: OTHER: Customized text message invitation ( Step 1a)|OTHER: Customized automatic phone call invitation (Step 1b)|OTHER: Secretary phone call (Step 2)|OTHER: Health professional face-to-face appointment (Step 3)|OTHER: Written Letter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: A Study to Evaluate Safety, Tolerability and P-Glucose After Multiple Ascending Oral Doses of AZD1656 in Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: AZD1656|DRUG: AZD1656
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Magnevist® Injection Enhanced MRA Compared to Non Contrast MRA for the Detection of Stenosis in the Calf and/or Pedal Arteries
Status: COMPLETED
Conditions: Stenosis
Interventions: DRUG: Gadopentetate dimeglumine (Magnevist)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy of Acupuncture in Radiotherapy-induced Dysphagia in Patients With Head and Neck Cancer
Status: UNKNOWN
Conditions: Acupuncture
Interventions: PROCEDURE: acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of the Serum Soluble Fractalkine as a Biomarker of Pulmonary Fibrosis in Systemic Sclerosis
Status: UNKNOWN
Conditions: Systemic Scleroderma
Interventions: BIOLOGICAL: blood samples
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Application of the Alfred SmartBag System After Ileostomy Creation in Colorectal Surgery: A Pilot Study
Status: UNKNOWN
Conditions: Ileostomy - Stoma|Ileostomy; Complications
Interventions: DEVICE: Alfred SmartBag
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety and Early Feasibility Study of the Harpoon Medical Device (EFS)
Status: COMPLETED
Conditions: Mitral Valve Regurgitation|Mitral Valve Prolapse|Mitral Valve Insufficiency
Interventions: DEVICE: Harpoon Medical Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stimulate Brain and Reduce Knee Pain Due to Degeneration
Status: UNKNOWN
Conditions: Knee Osteoarthritis
Interventions: OTHER: Transcranial direct current stimulation|OTHER: Conventional Physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Elranatamab in R/R Multiple Myeloma
Status: RECRUITING
Conditions: Refractory Multiple Myeloma|Relapse Multiple Myeloma|Multiple Myeloma
Interventions: DRUG: Elranatamab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non-Pharmacologic Alternatives for Childhood Obesity
Status: COMPLETED
Conditions: Obesity in Childhood
Interventions: DIETARY_SUPPLEMENT: Agave inulin|DIETARY_SUPPLEMENT: Curcumin|DIETARY_SUPPLEMENT: O3FA|BEHAVIORAL: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endovascular Repair of Abdominal Aortic Aneurysms
Status: COMPLETED
Conditions: Aortic Aneurysm, Abdominal
Interventions: DEVICE: Endovascular Repair of Abdominal Aortic Aneurysms Using TALENT AAA Stent Graft System
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Smoking Cessation Program for the Elderly
Status: RECRUITING
Conditions: Smoking Cessation|Aged|Telemedicine|Motivation
Interventions: BEHAVIORAL: Mobile health support|BEHAVIORAL: Financial incentive|BEHAVIORAL: Combine intervention|BEHAVIORAL: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Paliperidone Palmitate 6-Month Formulation
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: PP6M injection Dose 1|DRUG: PP6M injection Dose 2
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bevacizumab and Trastuzumab With Weekly Paclitaxel Followed, After Surgery, by Encapsuled Liposomal Doxorubicin, Cyclophosphamide and Trastuzumab as Adjuvant Treatment After Surgery on Women With Her2+ Breast Cancer
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: DRUG: Bevacizumab,Trastuzumab,Paclitaxel,Cyclophosphamide,Myocet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Pioglitazone on Insulin Resistance, Atherosclerosis Progression and Clinical Course of Coronary Heart Disease
Status: COMPLETED
Conditions: Adverse Effect|Atherosclerosis, Coronary|Insulin Resistance Syndrome
Interventions: DRUG: Pioglitazone 15 mg Tablet|DRUG: Isosorbide Dinitrate 10Mg Tablet|DRUG: Acetylsalicylic Acid 75Mg Tablet|DRUG: Bisoprolol Fumarate 2.5 MG Oral Tablet|DRUG: Rosuvastatin Calcium 20 MG Oral Tablet|DRUG: Ramipril 5 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Robotically-assisted Minimally-invasive Direct Coronary Artery Bypass With Stenting, Randomized Against Coronary Artery Bypass Graft Surgery
Status: NOT_YET_RECRUITING
Conditions: Coronary Artery Disease|Multivessel Coronary Artery Disease
Interventions: PROCEDURE: Coronary Artery Bypass Graft|PROCEDURE: Robotically-assisted minimally-invasive direct coronary artery bypass|PROCEDURE: Percutaneous Coronary Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Feasibility Study of Detection of IL-11 and Other Cytokines in the Exhaled Breath Condensate (EBC) and Blood of Healthy Volunteers
Status: RECRUITING
Conditions: Healthy
Interventions: OTHER: Exhaled breath condensate collection and blood draw
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: EFFICACY OF MORUS ALBA FRUIT EXTRACTS AND CHLORHEXIDINE ON SALIVARY STREPTOCOCCUS MUTANS AND pH LEVELS
Status: COMPLETED
Conditions: Dental Caries
Interventions: OTHER: Chlorhexidine Mouthwash|OTHER: Morus Alba 20%|OTHER: Morus Alba 30%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Assessing the Effects of Sublingual Sufentanil 30 µg on Postoperative Recovery
Status: TERMINATED
Conditions: Knee Arthroscopy
Interventions: DRUG: Sufentanil|DRUG: Fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Single Centre, Prospective, Observational Study to Assess the Use of the Rehabilitation Tool, GripAble, in Patients With Upper Limb Spasticity Receiving Botulinum Toxin-A (BoNT-A) in the United Kingdom (UK).
Status: COMPLETED
Conditions: Upper Limb Spasticity (ULS)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Use of Transcranial Ultrasound Treatment of Obsessive-Compulsive Disorder
Status: ENROLLING_BY_INVITATION
Conditions: Obsessive-Compulsive Disorder
Interventions: DEVICE: Focused Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of [68Ga]Ga-PentixaFor PET Imaging for the Identification of Unilateral Adrenal Secretion of ALdosterON in Patients With Primary Aldosteronism
Status: NOT_YET_RECRUITING
Conditions: Primary Aldosteronism
Interventions: COMBINATION_PRODUCT: [68Ga]Ga-PentixaFor PET imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study in Dentinal Hypersensitivity (DH) Participants to Assess the Efficacy of an Occluding Dentifrice.
Status: COMPLETED
Conditions: Dentin Sensitivity
Interventions: DEVICE: Experimental Oral Rinse 1|DEVICE: Experimental Oral Rinse 2|OTHER: Placebo Oral Rinse|DRUG: Fluoride toothpaste
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Alimta® Versus Its Combination With Carboplatin in Advanced Non-small-cell Lung Cancer in Patients Performance Status 2
Status: COMPLETED
Conditions: Non Small Cell Lung Carcinoma
Interventions: DRUG: Pemetrexed|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Quality of Life and Sexual Life in Hemodialysis Patients: Effects of an Intradialytic Exercise Program
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Kidney Diseases|Sexual Dysfunction
Interventions: OTHER: Intradialytic exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimizing the Anticoagulation Regimen of Enoxaparin During Percutaneous Coronary Intervention (OPTIENOX-PCI)
Status: COMPLETED
Conditions: Coronary Artery Disease|Percutaneous Coronary Intervention
Interventions: DRUG: Enoxaparin (Staged-dose PCI Group)|DRUG: Enoxaparin (Single-dose PCI Group)|DRUG: Enoxaparin (High-dose Group)|DRUG: Enoxaparin (Standard-dose Group)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: IV vs Oral Acetaminophen in Spine Fusion Perioperative Care
Status: ENROLLING_BY_INVITATION
Conditions: Multimodal Analgesic Approach
Interventions: DRUG: Ofirmev|DRUG: Per Os Acetaminophen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Aminolevulinic Acid in Visualizing a Tumor During Surgery in Patients With Glioblastoma Multiforme
Status: TERMINATED
Conditions: Adult Giant Cell Glioblastoma|Adult Glioblastoma|Adult Gliosarcoma|Recurrent Adult Brain Tumor
Interventions: DRUG: aminolevulinic acid|PROCEDURE: therapeutic conventional surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Temocillin Pharmacokinetic in Hemodialysis
Status: COMPLETED
Conditions: Gram-Negative Bacterial Infections|Renal Failure Chronic Requiring Hemodialysis
Interventions: DRUG: temocillin PK/PD in haemodialysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Eye Movement Desensitization and Reprocessing (EMDR) in Non-specific Chronic Back Pain
Status: COMPLETED
Conditions: Non-specific Chronic Back Pain
Interventions: BEHAVIORAL: Eye-Movement-Desensitization-Reprocessing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Comparison of Efficacy and Safety of the Mesenchymal Stem Cells From Adipose and Hyaluronic Acid
Status: UNKNOWN
Conditions: Knee Osteoarthritis
Interventions: BIOLOGICAL: Mesenchymal Stem Cells from adipose|BIOLOGICAL: Hyaluronic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Reducing Disparity in Receipt of Mother's Own Milk in Very Low Birth Weight Infants
Status: RECRUITING
Conditions: Pumping, Breast|Milk, Human|Infant, Very Low Birth Weight|Preterm Birth
Interventions: BEHAVIORAL: NICU Acquires MOM|BEHAVIORAL: Mother Provides MOM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: AZD2423 Single Ascending Dose Study in Healthy Japanese Subjects
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: AZD2423|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Oxcarbazepine for the Treatment of Chronic Peripheral Neuropathic Pain
Status: COMPLETED
Conditions: Polyneuropathy|Peripheral Nerve Injury|Postherpetic Neuralgia
Interventions: DRUG: Oxcarbazepine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Contact Lenses With New UV-blocker Manufactured With Different Techniques
Status: COMPLETED
Conditions: Correction of Refraction Error|Attenuation of Bright Light
Interventions: DEVICE: senofilcon A TEST Lens|DEVICE: senofilcon A CONTROL Lens
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Sirolimus Treatment in Hospitalized Patients With COVID-19 Pneumonia
Status: COMPLETED
Conditions: COVID-19
Interventions: DRUG: Sirolimus|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized, Placebo-Controlled, Double-Blind Pilot Study of Pioglitazone Hydrochloride in Severe, Refractory Asthma
Status: COMPLETED
Conditions: Severe, Refractory Asthma|Airway Inflammation|Airflow Obstruction
Interventions: DRUG: Pioglitazone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Liberal vs. Restricted Post-discharge Opioid Prescribing Following Midurethral Sling
Status: COMPLETED
Conditions: Postoperative Pain|Opioid Use
Interventions: OTHER: Liberal post-discharge opioid prescribing|OTHER: Restricted post-discharge opioid prescribing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Subjects With Psoriatic Arthritis to Investigate the Effectiveness of Adalimumab Introduction Compared With Methotrexate Dose Escalation (CONTROL)
Status: COMPLETED
Conditions: Psoriatic Arthritis
Interventions: DRUG: methotrexate (MTX)|BIOLOGICAL: adalimumab (ADA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radioimmunotherapy (211At-OKT10-B10) and Chemotherapy (Melphalan) Before Stem Cell Transplantation for the Treatment of Multiple Myeloma
Status: WITHDRAWN
Conditions: Plasma Cell Myeloma
Interventions: BIOLOGICAL: Astatine At 211 Anti-CD38 Monoclonal Antibody OKT10-B10|DRUG: Melphalan|PROCEDURE: Peripheral Blood Stem Cell Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Screening for Chromosomal Microarrangements by CGH-array in Developmental Anomalies of the Skin Suggestive of Mosaicism.
Status: COMPLETED
Conditions: Malformations With Skin Manifestations Suggesting Mosaicism
Interventions: BIOLOGICAL: Peripheral blood samples in EDTA tubes|PROCEDURE: Skin biopsies
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Laser Ablation for Intermediate and Advanced Hepatocellular Carcinoma With Portal Vein Tumor Thrombus
Status: COMPLETED
Conditions: Hepatocellular Carcinoma|Laser Ablation|Portal Vein Tumor Thrombus
Interventions: PROCEDURE: LA|PROCEDURE: 3D-CRT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: JASPER Implementation in NFLD
Status: ACTIVE_NOT_RECRUITING
Conditions: Autism Spectrum Disorder
Interventions: BEHAVIORAL: Alternate Coaching and Video Feedback Phase 1|BEHAVIORAL: Weekly Coaching in Phase 1|BEHAVIORAL: Weekly Coaching plus Intensive Refresher Course Phase 2|BEHAVIORAL: Weekly Coaching plus Peer Coaching Phase 2|BEHAVIORAL: Video Feedback Only Phase 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: WBRT & Erlotinib in Advanced NSCLC and Brain Metastases
Status: TERMINATED
Conditions: Lung Cancer|Metastatic Cancer
Interventions: DRUG: erlotinib hydrochloride|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Diabetic Macular Edema (DME) Treatment With Ranibizumab and Dexamethasone or Ranibizumab Only.
Status: UNKNOWN
Conditions: Macular Edema
Interventions: DRUG: Ranibizumab Ophthalmic and Intravitreal Dexamethasone|DRUG: Ranibizumab Ophthalmic only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Trial of TST of PD 0332991 Followed by Cytarabine and Mitoxantrone for Adults With Relapsed and Refractory Acute Leukemias and High-Risk Myelodysplasia
Status: TERMINATED
Conditions: Relapsed Acute Leukemia|Refractory Acute Leukemia|High-Risk Myelodysplasia
Interventions: DRUG: PD 0332991
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dipole Density Mapping of Right and Left Atrial Supraventricular Tachycardia
Status: WITHDRAWN
Conditions: Supraventricular Tachycardia
Interventions: DEVICE: Mapping with the Acutus Medical System followed by Ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Usefulness and Predictive Capacity of ANI and SPI of the Hemodynamic Response
Status: COMPLETED
Conditions: Pain|Tachycardia|Hypertension
Interventions: DEVICE: Metrodoloris Medical System|DEVICE: Aisys® care station, Acertys
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Investigating the Effects of Dietary Phospholipids on Measures of Human Brain Health and Psychological Wellbeing
Status: RECRUITING
Conditions: Mood|Cognitive Change|Well-Being, Psychological
Interventions: DIETARY_SUPPLEMENT: Active|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Building Resilience During the COVID-19 Pandemic: a Randomized Controlled Trial
Status: RECRUITING
Conditions: Healthy|COVID-19|Distress, Emotional
Interventions: BEHAVIORAL: RASMUS Resilience Training|BEHAVIORAL: Progressive Muscle Relaxation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Penetrance of Third Generation Fluoroquinolones in Eyes With Functioning Filtering Blebs
Status: COMPLETED
Conditions: Cataract
Interventions: DRUG: Ofloxacin 0.3%|DRUG: Ciprofloxacin 0.3%|DRUG: Levofloxacin 0.5%|DRUG: Ofloxacin 400mg|DRUG: Ciprofloxacin 400mg|DRUG: Levofloxacin 250mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Feasibility Randomized Trial for an Intensive Memory-Focused Training Program for School Aged Children With Acquired br.Inj.
Status: COMPLETED
Conditions: Acquired Brain Injury
Interventions: OTHER: rehabilitation|OTHER: Intensive Memory-Focused Training Program (IM-FTP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Head to Head Mailed Cologuard to Mailed FIT
Status: RECRUITING
Conditions: Colorectal Cancer
Interventions: DIAGNOSTIC_TEST: Cologuard|DIAGNOSTIC_TEST: Fecal Immunochemical Test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Evaluation of Alpha-Lipoic Acid in Diabetic Cardiomyopathy
Status: TERMINATED
Conditions: Diabetic Cardiomyopathies
Interventions: DIETARY_SUPPLEMENT: Physiomance acide lipoïque gold|DIETARY_SUPPLEMENT: Placebo - Physiomance acide lipoïque gold
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effect of Stair Climbing and Descending on Postprandial Blood Glucose
Status: COMPLETED
Conditions: Postprandial Blood Glucose
Interventions: OTHER: 1 minute of stair climbing and descending|OTHER: 3 minute of stair climbing and descending|OTHER: 10 minute of stair climbing and descending
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to See if we Can Predict How Your Liver Tumor or Liver Metastases Will Respond to Trans-Arterial Embolization (TAE)
Status: WITHDRAWN
Conditions: Liver Cancer|Liver Metastases
Interventions: PROCEDURE: Hepatic trans-arterial embolization (TAE)|DEVICE: MRI/CT scan|PROCEDURE: biopsy|OTHER: blood draw
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Alster Man and Machine: Comparison of Manual and Mechanical Remote Robotic Catheter Ablation for Drug-Refractory Atrial Fibrillation
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: PROCEDURE: Pulmonary vein isolation with radiofrequency current
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Diabetes Control on Outcome in Hospitalized Patients: A National Israeli Study
Status: UNKNOWN
Conditions: Diabetes
Interventions: DRUG: Basal bolus insulin regimen (tight glucose control)|DRUG: Basal bolus insulin regimen (standard control)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Does Inspection During Insertion Improve Adenoma Yields During Colonoscopy?
Status: COMPLETED
Conditions: Colorectal Cancer|Colorectal Polyps
Interventions: PROCEDURE: Inspection during insertion|PROCEDURE: Inspection during withdrawal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Impact of tDCS on Emotional Processing in Healthy Subjects.
Status: TERMINATED
Conditions: Transcranial Direct Current Stimulation
Interventions: DEVICE: tDCS Anode session|DEVICE: tDCS Cathode session|DEVICE: tDCS Placebo session
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Denosumab Administration After Spinal Cord Injury
Status: UNKNOWN
Conditions: Osteoporosis|Spinal Cord Injury
Interventions: DRUG: Denosumab|DRUG: Placebo (identical Denosumab volume of normal saline)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Aerobic Exercise in Parkinson's Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Parkinson's Disease
Interventions: BEHAVIORAL: Aerobic walking|BEHAVIORAL: Usual care with PD specific health education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Study to Evaluate JCXH-105, an SrRNA-based Herpes Zoster Vaccine
Status: NOT_YET_RECRUITING
Conditions: Herpes Zoster (HZ)|Infectious Diseases|Shingles
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Plant Stanols on Immune Function in Asthma Patients
Status: COMPLETED
Conditions: Asthma|Allergy
Interventions: DIETARY_SUPPLEMENT: Plant stanol enriched soy-based yoghurt|DIETARY_SUPPLEMENT: Soy-based yoghurt without added plant stanols
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Continuation Electroconvulsive Therapy Vs Medication to Prevent Relapses in Patients With Major Depressive Disorder
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: Nortriptyline-lithium (NOR-Li)|PROCEDURE: Bilateral electroconvulsive therapy (ECT)|DRUG: Continuation therapy|BEHAVIORAL: Continuation ECT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: SINGLE|Primary Purpose: TREATMENT