pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Effects of Mental Practice for Mobility in Post-stroke Hemiparesis
Status: UNKNOWN
Conditions: Stroke|Hemiparesis
Interventions: OTHER: Mental practice|OTHER: Cognitive training and Relaxation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacogenetic Prediction of Metoprolol Effectiveness
Status: TERMINATED
Conditions: Hypertension
Interventions: DRUG: metoprolol succinate|GENETIC: Genotyping|PROCEDURE: CYP2D6 Phenotyping
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy Followed by Donor Stem Cell Transplant in Treating Patients With Relapsed or High-Risk Primary Refractory Hodgkin Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: DRUG: cyclophosphamide|DRUG: cyclosporine|DRUG: fludarabine phosphate|DRUG: gemcitabine hydrochloride|DRUG: ifosfamide|DRUG: mechlorethamine hydrochloride|DRUG: melphalan|DRUG: methotrexate|DRUG: mycophenolate mofetil|DRUG: prednisone|DRUG: procarbazine hydrochloride|DRUG: vincristine sulfate|DRUG: vinorelbine tartrate|PROCEDURE: allogeneic bone marrow transplantation|PROCEDURE: allogeneic hematopoietic stem cell transplantation|PROCEDURE: nonmyeloablative allogeneic hematopoietic stem cell transplantation|PROCEDURE: peripheral blood stem cell transplantation|PROCEDURE: umbilical cord blood transplantation|RADIATION: total-body irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Renal Sympathetic Denervation From the Adventitia on Resistant Hypertension（RSDARH）
Status: UNKNOWN
Conditions: Resistant Hypertension
Interventions: DEVICE: Radiofrequency ablation instruments
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Precision and Accuracy Study of the Codman Valve Position Verification (VPV) System.
Status: COMPLETED
Conditions: Hydrocephalus|Normal Pressure Hydrocephalus
Interventions: DEVICE: Codman VPV System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Informative Value of Determining the Level of NF-κB Translocation in Lymphocyte Populations in Children With Psoriasis
Status: COMPLETED
Conditions: Psoriasis Vulgaris
Interventions: DIAGNOSTIC_TEST: Peripheral blood samples were obtained following the standard procedures.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: pBFS-guided rTMS Over DMPFC for Treatment-Resistant Depression
Status: RECRUITING
Conditions: Treatment Resistant Depression|Major Depressive Disorder
Interventions: DEVICE: active rTMS treatment|DEVICE: sham rTMS treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Difluprednate Ophthalmic Emulsion in the Treatment of Uveitis
Status: COMPLETED
Conditions: Anterior Uveitis
Interventions: DRUG: Difluprednate Ophthalmic Emulsion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Cardiac and Metabolic Effects of Semaglutide in Heart Failure With Preserved Ejection Fraction
Status: RECRUITING
Conditions: Cardiomyopathy|Heart Failure With Preserved Ejection Fraction (HFpEF)|Obesity
Interventions: DRUG: Semaglutide|DRUG: Placebo|BEHAVIORAL: Counselling on healthy lifestyle intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Donor Stem Cell Transplant in Treating Patients With Relapsed Hematologic Cancer
Status: COMPLETED
Conditions: Leukemia|Lymphoma|Multiple Myeloma|Plasma Cell Neoplasm|Myelodysplastic Syndromes|Myeloproliferative Neoplasms
Interventions: BIOLOGICAL: anti-thymocyte globulin|BIOLOGICAL: G-CSF|DRUG: busulfan|DRUG: fludarabine phosphate|DRUG: methotrexate|DRUG: mycophenolate mofetil|DRUG: tacrolimus|PROCEDURE: allogeneic cell transplantation|DRUG: allopurinol
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long Term Safety Study of NVA237 vs QAB149 in COPD Patients
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: DRUG: NVA237|DRUG: Long-acting beta 2-agonist (LABA)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: LZM009 to Treat Patients With Advanced Solid Tumors
Status: COMPLETED
Conditions: Solid Tumor
Interventions: BIOLOGICAL: LZM009,recombinant humanized anti-PD-1 monoclonal antibody for injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Potential Effects of Electronic Nicotine Delivery System Flavor Regulations on African American Menthol Smokers
Status: RECRUITING
Conditions: Electronic Nicotine Delivery System Flavors
Interventions: OTHER: Tobacco product administration and assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Compare the Efficacy of Rapydan Versus Tetracaine Gel
Status: WITHDRAWN
Conditions: Healthy|Anesthesia
Interventions: DRUG: Rapydan|DRUG: tetracaine gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate ONO-4474 in Patients With Pain Due to Osteoarthritis of the Knee
Status: TERMINATED
Conditions: Osteoarthritis, Knee|Pain
Interventions: DRUG: ONO-4474|DRUG: Placebo matching ONO-4474
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Exploratory Bioavailability of Fentanyl Sublingual Spray Under Fasting Conditions
Status: COMPLETED
Conditions: Bioavailability
Interventions: DRUG: Fentanyl Sublingual Spray (FSS)|DRUG: Fentanyl Citrate Injection (FCI)|DRUG: Naltrexone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Hormonal Contraceptives on Liver Proteins and Coagulation Factors: A Comparison of a Contraceptive Vaginal Ring and an Oral Contraceptive
Status: COMPLETED
Conditions: Contraception
Interventions: DRUG: Nestorone/ethinyl estradiol contraceptive vaginal ring; levonorgestrel/ethinyl estradiol oral contraceptive
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Phase I Pilot Study of CD34 Enriched, Fanconi's Anemia Complementation Group C Gene Transduced Autologous Peripheral Blood Stem Cell Transplantation in Patients With Fanconi's Anemia
Status: UNKNOWN
Conditions: Fanconi's Anemia
Interventions: DRUG: filgrastim|GENETIC: Autologous stem cells transduced with FACC retroviral vector|PROCEDURE: Autologous Stem Cell Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: N10: A Study of Reduced Chemotherapy and Monoclonal Antibody (mAb)-Based Therapy in Children With Neuroblastoma
Status: RECRUITING
Conditions: High-risk Neuroblastoma|Neuroblastoma|Childhood Neuroblastoma
Interventions: BIOLOGICAL: DANYELZA|BIOLOGICAL: Sargramostim|DRUG: Cytoxan|DRUG: Topotecan|DRUG: Vincristine|DRUG: Doxorubicin|DRUG: Ifosfamide|DRUG: Etoposide|DRUG: Carboplatin|DRUG: Irinotecan|DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Morphine, Dyspnea, Exercise and COPD
Status: UNKNOWN
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Morphine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: S0022:Combination Chemotherapy and Radiation Therapy in Treating Patients With Stage IIIB Non-Small Cell Lung Cancer
Status: TERMINATED
Conditions: Lung Cancer
Interventions: DRUG: cisplatin|DRUG: docetaxel|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TelePharmaceutical Care Diabetes Trial
Status: UNKNOWN
Conditions: Diabete Mellitus|Diabete Type 2|Telemedicine|Telehealth
Interventions: BEHAVIORAL: Telepharmaceutical Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: COMPANION: A Couple Intervention Targeting Cancer-related Fatigue
Status: ACTIVE_NOT_RECRUITING
Conditions: Neoplasms|Fatigue
Interventions: BEHAVIORAL: Samen Minder Moe (Dutch intervention name)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Non-surgical Spinal Decompression Therapy and Outcomes
Status: NOT_YET_RECRUITING
Conditions: Low Back Pain|Herniation, Disc|Sciatic Radiculopathy|Intervertebral Disc Stenosis of Neural Canal|Intervertebral Disc Injury
Interventions: DEVICE: NSSD|DEVICE: Sham NSSD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Building Capacity and Promoting Smoking Cessation in the Community Via "Quit to Win" Contest 2018
Status: COMPLETED
Conditions: Smoking Cessation
Interventions: BEHAVIORAL: Personalized active referral plus financial incentive|BEHAVIORAL: AWARD advice|BEHAVIORAL: Warning leaflet|BEHAVIORAL: Referral card|BEHAVIORAL: COSH booklet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: American Ginseng to Improve HIV-Associated Fatigue: A Randomized, Placebo-Controlled, Parallel Design, Multiple-Dose Clinical Trial
Status: COMPLETED
Conditions: HIV/AIDS-associated Fatigue
Interventions: DRUG: American ginseng|DIETARY_SUPPLEMENT: Placebo for American ginseng
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: First In Human Study To Evaluate The Safety, Tolerability, Pharmacokinetics And Pharmacodynamics Of PF-04427429 Administered Intravenously To Healthy Adult Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: PF-04427429|DRUG: PF-04427429|DRUG: PF-04427429
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Laser Therapy to Treat the Dry Mouth of Sjogren's Syndrome
Status: COMPLETED
Conditions: KERATOCONJUNCTIVITIS SICCA|XEROSTOMIA|SICCA SYNDROME|PRIMARY SJOGREN SYNDROME
Interventions: DEVICE: Lasertherapy|DEVICE: Sham Lasertherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neuspera's Implantable Sacral Nerve Stimulation System in Patients With Symptoms of Urinary Urgency Incontinence (UUI)
Status: ACTIVE_NOT_RECRUITING
Conditions: Urinary Urgency Incontinence
Interventions: DEVICE: Neuspera Implantable Sacral Nerve Stimulation System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Leveraging mHealth Messaging to Promote Adherence in Teens With CKD
Status: COMPLETED
Conditions: Chronic Kidney Diseases|Adherence, Medication|Communication
Interventions: BEHAVIORAL: mHealth Messaging Intervention Group|BEHAVIORAL: Standard mHealth Messaging Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Intensive Blood Pressure Reduction in Acute Cerebral Haemorrhage
Status: COMPLETED
Conditions: CVA (Cerebrovascular Accident)|Cerebral Hemorrhage|Intracranial Hemorrhages
Interventions: DRUG: Labetalol Hydrochloride|DRUG: Metoprolol tartrate|DRUG: Hydralazine Hydrochloride|DRUG: Glycerol Trinitrate|DRUG: Phentolamine mesylate|DRUG: Nicardipine|DRUG: Urapidil|DRUG: Esmolol|DRUG: Clonidine|DRUG: Enalaprilat|DRUG: Nitroprusside
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Mental and Physical Fatigue to Force Production in Adults
Status: COMPLETED
Conditions: Mental Fatigue|Muscle Weakness
Interventions: OTHER: Physical Fatiguing Task only|OTHER: Physical and Mental Fatiguing Task
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Effectiveness of START (Startle Adjuvant Rehabilitation Therapy) in Enhancing Arm Function Post-Stroke
Status: RECRUITING
Conditions: Stroke
Interventions: OTHER: START - Startle Adjuvant Rehabilitation Therapy|OTHER: Sham Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Analgesic Use for Pain Relief in Scorpion Sting
Status: COMPLETED
Conditions: Scorpion Stings
Interventions: DRUG: paracetamol|DRUG: Dexketoprofen Trometamol|DRUG: Lidocaine topical|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Mesenchymal Stem Cell Conditioned Medium-derived Pleiotropic Factor in Treating Residual Burn Wound
Status: UNKNOWN
Conditions: Mesenchymal Stem Cell-derived Pleiotropic Factor in Treating Residual Burn Wound
Interventions: BIOLOGICAL: epidermal growth factor|BIOLOGICAL: mesenchymal stem cell conditioned medium-derived pleiotropic factor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Antioxidant Supplementation on Multiple Endurance Race Performance, Physiology, and Recovery.
Status: COMPLETED
Conditions: Oxidative Stress|Muscle Strength|Resistance Training|Body Composition|Muscle Damage
Interventions: OTHER: Cross Training Course|DIETARY_SUPPLEMENT: Oceanix
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Regulating Homeostatic Plasticity and the Physiological Response to rTMS
Status: TERMINATED
Conditions: Tinnitus
Interventions: DEVICE: sham tDCS and sham rTMS|DEVICE: sham tDCS and active rTMS|DEVICE: active tDCS and active rTMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study Evaluating the Safety and Efficacy of Islatravir in Combination With Lenacapavir in Virologically Suppressed People With HIV
Status: ACTIVE_NOT_RECRUITING
Conditions: HIV-1 Infection
Interventions: DRUG: ISL|DRUG: LEN|DRUG: B/F/TAF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reduced Intensity Conditioning and Familial HLA-Mismatched BMT for Non-Malignant Disorders
Status: RECRUITING
Conditions: Severe Sickle Cell Disease|Bone Marrow Failure Syndromes|Metabolic Disorders|Immunologic Disorders|Hemoglobinopathies|Non-malignant Disorders
Interventions: DRUG: RIC regimen|DRUG: GVHD prophylaxis regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral Bacterial Extract for the Prevention of Wheezing Lower Respiratory Tract Illness
Status: ACTIVE_NOT_RECRUITING
Conditions: Asthma|Wheezing
Interventions: DRUG: Broncho-Vaxom (BV)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effects Of Low Level Laser Therapy On Tooth Movement,Treatment Related Complications Of Gingivitis,Periodontitis And Pain In Fixed Orthodontic Patients
Status: UNKNOWN
Conditions: Gingivitis|Pain|Periodontitis|Tooth Migration
Interventions: DEVICE: low level laser therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effects of Conventional Versus Skeletally Anchored Facemask in Treatment of the Prepubertal Skeletal Class III Patients
Status: UNKNOWN
Conditions: Maxillary Deficiency|Maxillary Retrusion
Interventions: OTHER: Maxillary protraction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Orange Juice on Glycemic Response
Status: COMPLETED
Conditions: Effect of Food on Postprandial Hyperglycemia
Interventions: OTHER: control|OTHER: test meal 1|OTHER: test meal 2|OTHER: test meal 3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Slow Opioid Tapering Pilot Study of Patients Using Chronic Opioid Therapy
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Pain|Opioid Use
Interventions: OTHER: Slow Tapering of Chronic Opioid Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Assessing PA-824 for Tuberculosis (the APT Trial)
Status: COMPLETED
Conditions: Pulmonary Tuberculosis
Interventions: DRUG: PA-824|DRUG: Rifampin|DRUG: Rifabutin|DRUG: Pyrazinamide|DRUG: Ethambutol|DRUG: Isoniazid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Zinc, β-carotene, and Vitamin D3 in Preterm Delivery Through Placental MyD88, TRIF, NFkB, and IL-1β
Status: COMPLETED
Conditions: PreTerm Birth
Interventions: DRUG: Zinc|DRUG: Nifedipine|DRUG: Beta Carotene|DRUG: Vitamin D3|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Lenalidomide Plus Melphalan as a Preparative Regimen for Autologous Stem Cell Transplantation in Relapsed Multiple Myeloma: A Phase 1 / 2 Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: lenalidomide|DRUG: melphalan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation Of CanADVICE+®M-Health System To Support Breast Cancer Patients Receiving Capecitabine
Status: COMPLETED
Conditions: Metastatic Breast Cancer
Interventions: DEVICE: CanADVICE+® (smart phone app)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: CGM (Continuous Glucose Monitoring) Use in Diagnosis of Spontaneous and Reactive Hypoglycaemia
Status: TERMINATED
Conditions: Hypoglycemia, Reactive|Hypoglycaemia Night|Hypoglycemia Non-Diabetic|Hypoglycemia Unawareness|Insulinoma|Insulinoma; Malignant, Pancreas|Insulin Hypoglycemia|Insulin Resistance|Spontaneous Hypoglycemia|Neuro Endocrine Tumours
Interventions: DEVICE: use of continuous glucose monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Alternative Paracetamol Treatments for the Neonate With a hsPDA
Status: UNKNOWN
Conditions: Ductus Arteriosus, Patent
Interventions: DRUG: Rectal Solution|DRUG: Intravenous Infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transition cAre inteRvention tarGeted to High-risk patiEnts To Reduce rEADmission
Status: COMPLETED
Conditions: Patient Readmission
Interventions: OTHER: TARGET
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Bariatric Surgery and Fatty Liver Disease
Status: COMPLETED
Conditions: Morbid Obesity|Diabetes|Hypertension
Interventions: DIAGNOSTIC_TEST: Biochemistry analysis|DIAGNOSTIC_TEST: NAFLD fibrosis score|OTHER: BMI measurement|DIAGNOSTIC_TEST: Fibrosis 4 Index|DIAGNOSTIC_TEST: Fatty Liver Index
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety Study of GNbAC1 Monoclonal Antibody in Healthy Male Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: GNbAC1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Endothelial Dysfunction During Aortic Valvular Replacement by Bioprosthesis With and Without Extracorporeal Circulation
Status: COMPLETED
Conditions: Endothelial Dysfunction|Aortic Valve Disease
Interventions: OTHER: Study of endothelial function biological markers
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Titanium Elastic Nailing Versus Hip Spica Cast in Treatment of Femoral Fractures in Children
Status: COMPLETED
Conditions: Femoral Shaft Fracture
Interventions: PROCEDURE: titanium elastic nailing|DEVICE: Hip spica casting
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of 18F-Florbetaben Whole-body PET for the Detection of Cardiac and Extracardiac Sites of Amyloid Deposits
Status: RECRUITING
Conditions: Cardiac Amyloidosis
Interventions: DRUG: Neuraceq PET/CT imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: CAR-T Cells Therapy in Relapsed/Refractory Multiple Myeloma
Status: TERMINATED
Conditions: Relapsed/Refractory Multiple Myeloma(MM)
Interventions: BIOLOGICAL: CART therapy in Relapsed/Refractory multiple myeloma
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study of IV Peramivir in Hospitalized Subjects With Confirmed or Suspected Influenza
Status: COMPLETED
Conditions: Seasonal Influenza|Cough|Sore Throat|Nasal Congestion|Myalgia|Headache|Fatigue
Interventions: DRUG: Peramivir|DRUG: Peramivir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Erythropoietin to Prevent Unnecessary Transfusions In Patients With Cyanotic CHD - A Prospective Control Trial
Status: TERMINATED
Conditions: Cyanotic Congenital Heart Disease|Anemia|Cyanosis|Congenital Heart Disease
Interventions: DRUG: Epoetin Alfa and Iron|DRUG: Iron
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Patient's Choice in the Reduction of Their Treatment in Women Over 65 Year With Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer
Interventions: RADIATION: Whole breast radiotherapy|RADIATION: Intra Operative Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Maribavir Versus Oral Ganciclovir For The Prevention of Cytomegalovirus (CMV) Disease in Liver Transplant Recipients
Status: COMPLETED
Conditions: Cytomegalovirus Infections
Interventions: DRUG: maribavir|DRUG: ganciclovir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Lanreotide Autogel in Non-functioning Entero-pancreatic Endocrine Tumours
Status: COMPLETED
Conditions: Endocrine Tumors
Interventions: DRUG: lanreotide (Autogel formulation)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: T-cell And General Immune Response to Seasonal Influenza Vaccine (SLVP018) Year 2, 2010
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: High Dose Fluzone® (intramuscular)|BIOLOGICAL: Fluzone® (intramuscular)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Single-dose Nicotine Pharmacokinetics With Four Oral Nicotine Replacement Products
Status: COMPLETED
Conditions: Tobacco Dependence
Interventions: DRUG: Nicotine Medicated Gum|DRUG: 4 mg Nicotine Gum|DRUG: 2 mg Nicotine Gum|DRUG: 4 mg Nicotine Lozenge
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Reverse Genetic H9N2 Influenza Vaccine Study in Adults
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Reverse Genetic (RG) reassortant A/H9N2 influenza vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Bipolar RF Microneedling for Improved Laxity and Lift of the Submental and Neck Tissue and Effect on Elastin
Status: WITHDRAWN
Conditions: Skin Laxity
Interventions: DEVICE: Dermal Handpiece / SubQ Handpiece
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: QXZS in Menopausal Syndrome Based on 16S rRNA Sequencing Technology
Status: RECRUITING
Conditions: Menopause
Interventions: DRUG: Qingxin Zishen decoction|DRUG: Femoston
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rosiglitazone Versus Theophylline in Asthmatic Smokers
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: rosiglitazone|DRUG: theophylline|DRUG: beclomethasone|DRUG: inhaled beclomethasone and oral theophylline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Improving Occupational Therapy Students' Holistic Care Competencies Through a Structured Holistic Thinking Curriculum: a Mixed Design
Status: RECRUITING
Conditions: Holistic Care Competencies of Occupational Therapy Students
Interventions: OTHER: Structured holistic thinking course(2 hr)|OTHER: Clinical practice training
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Quality of Cardiopulmonary Resuscitation Without and With Defibrillator Feedback
Status: COMPLETED
Conditions: Cardiac Arrest
Interventions: DEVICE: automated direct feedback on CPR from defibrillator
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Positron Emission Tomography in Extrapulmonary Tuberculosis
Status: COMPLETED
Conditions: Extrapulmonary Tuberculosis|Lymph Node Tuberculosis|Bone Tuberculosis
Interventions: OTHER: Positron Emission Tomography with 18F-Fluoro-deoxy-glucose
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of Gemcitabine/Carboplatin/Bevacizumab to Treat Ovarian, Fallopian Tube or Primary Peritoneal Cancer
Status: COMPLETED
Conditions: Ovarian Cancer|Fallopian Tube Cancer|Peritoneal Cancer
Interventions: DRUG: Bevacizumab|DRUG: Gemcitabine|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of a Probiotic-based Formula on Digestive Symptoms and Mood in Ultra Marathon Runners
Status: COMPLETED
Conditions: Signs and Symptoms
Interventions: DIETARY_SUPPLEMENT: Experimental product|DIETARY_SUPPLEMENT: Control product
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Collagen Sponge Versus Collagen Membrane on Ridge Preservation of Periodontally Compromised Teeth
Status: RECRUITING
Conditions: Periodontitis
Interventions: PROCEDURE: alveolar ridge preservation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized Study to Examine the Ability of a Caffeine-Based Energy Drink to Impact Energy Expenditure, Fat Oxidation, Reaction Time, and Other Perceptual Indicators
Status: COMPLETED
Conditions: Energy Expenditure|Cognition|Reaction Time
Interventions: DIETARY_SUPPLEMENT: Caffeine-Based Energy Drink|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Treatment of Chronic Bothersome Tinnitus Using Cognitive Training and D-cycloserine
Status: COMPLETED
Conditions: Tinnitus
Interventions: BEHAVIORAL: Cognitive Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Pancreas Interception Center (PIC) for Early Detection, Prevention, and Novel Therapeutics
Status: RECRUITING
Conditions: Pancreatic Ductal Adenocarcinoma|Pancreatic Cyst|Chronic Pancreatitis|Fatty Pancreas|Genetic Pancreatic Cancer|Genetic Pancreatitis|BRCA Mutation|Lynch Syndrome|FAP|Familial Atypical Multiple Mole-Melanoma|PALB2 Gene Mutation|Peutz-Jeghers Syndrome|Ataxia Telangiectasia
Interventions: OTHER: Data collection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Intracoronary Infusion of Autologous Bone Marrow Cells for Treatment of Idiopathic Dilated Cardiomyopathy
Status: COMPLETED
Conditions: Dilated Cardiomyopathy
Interventions: PROCEDURE: Intracoronary infusion of autologous bone marrow cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Digital Therapeutic on Metabolic Parameters
Status: COMPLETED
Conditions: Insulin Resistance|Prediabetic State|Diabetes Mellitus, Type 2|Obesity
Interventions: DEVICE: Vitadio|BEHAVIORAL: Conventional high-intensity lifestyle intervention program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Enzalutamide and Mifepristone in Treating Patients With Metastatic Hormone Resistant Prostate Cancer
Status: COMPLETED
Conditions: Hormone-resistant Prostate Cancer|Recurrent Prostate Cancer|Stage IV Prostate Cancer
Interventions: DRUG: enzalutamide|DRUG: mifepristone|OTHER: laboratory biomarker analysis|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Selenium Supplementation Versus Placebo in Patients With Graves' Hyperthyroidism
Status: UNKNOWN
Conditions: Graves' Hyperthyroidism
Interventions: DIETARY_SUPPLEMENT: Selenium|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Topical Cyclosporine 0.05% in the Prevention of Ocular Surface Inflammation Secondary to Pterygia
Status: COMPLETED
Conditions: Pterygia
Interventions: DRUG: Topical Cyclosporine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Percutaneous Device Closure for Significant Paravalvular Leakage After Transcatheter or Surgical Valve Replacement
Status: WITHDRAWN
Conditions: Cardiac Valves|Heart Valve Diseases|Valvular Insufficiency
Interventions: DEVICE: Percutaneous Device Closure: Vascular plug
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Simultaneous Injection of Propofol and Rocuronium in Inducing General Anesthesia
Status: COMPLETED
Conditions: Anesthesia; Functional
Interventions: DRUG: administration of propofol and rocuronium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Bupropion in Sexual Dysfunction Among Methadone Maintenance Treatment Men
Status: COMPLETED
Conditions: Sexual Dysfunctions, Psychological|Hypoactive Sexual Desire Disorder|Erectile Dysfunctions
Interventions: DRUG: Bupropion hydrochloride sustained-release|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of the Addition of Metyrapone to Antidepressant Therapy in Depression With Dexamethasone Suppression Test Non-suppression.
Status: UNKNOWN
Conditions: Depressive Disorder|Hormone Disturbance
Interventions: DRUG: Metyrapone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Development of Pregnenolone as a Treatment for Depression
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: Pregnenolone 500 mg|DRUG: Pregnenolone 800 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Modafinil on Olanzapine Weight Gain
Status: COMPLETED
Conditions: Weight Gain
Interventions: DRUG: Olanzapine plus modafinil|DRUG: Olanzapine plus placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Tissue Reinforcement of Incisional Closure Among High Risk Patients
Status: TERMINATED
Conditions: Wound Complication
Interventions: DEVICE: Biologic Mesh|PROCEDURE: Small Bites|PROCEDURE: Large Bites
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Subcutaneous Versus Intravenous Administration of Bortezomib in Patients With Multiple Myeloma in China
Status: UNKNOWN
Conditions: Multiple Myeloma Proved by Laboratory Tests
Interventions: OTHER: Subcutaneous bortezomib|OTHER: Intravenous bortezomib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Comparing Travoprost Intraocular Implants to Timolol Ophthalmic Solution
Status: COMPLETED
Conditions: Glaucoma Open-angle
Interventions: DRUG: Travoprost Intraocular Implant, high elution|DRUG: Travoprost Intraocular Implant, low elution|DRUG: Timolol Maleate Ophthalmic Solution, 0.5%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Point-Of-Care Testing for Congenital Syphilis in Mothers and Newborns
Status: WITHDRAWN
Conditions: Maternal Syphilis During Pregnancy - Baby Not Yet Delivered|Congenital Syphilis
Interventions: DIAGNOSTIC_TEST: Syphilis Health Check POC-test (Diagnostics Direct LLC, NJ)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: VivaSight Left-sided Double Lumen Tube Study
Status: COMPLETED
Conditions: Intubation, Intratracheal
Interventions: DEVICE: intubation with VivaSight double-lumen tube|DEVICE: intubation with standard double-lumen tube|PROCEDURE: fiberoptic bronchoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Transversus Abdominis Plane Block Using Dexmedetomidine and Bupivacaine
Status: COMPLETED
Conditions: Laparoscopic Orcheopexy
Interventions: DRUG: Dexmedetomidine|DRUG: Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pegylated Liposomal Doxorubicin Hydrochloride and Carboplatin Followed by Surgery and Paclitaxel in Treating Patients With Triple Negative Stage II-III Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Estrogen Receptor-negative Breast Cancer|HER2-negative Breast Cancer|Progesterone Receptor-negative Breast Cancer|Stage IIA Breast Cancer|Stage IIB Breast Cancer|Stage IIIA Breast Cancer|Stage IIIB Breast Cancer|Stage IIIC Breast Cancer|Triple-negative Breast Cancer
Interventions: DRUG: pegylated liposomal doxorubicin hydrochloride|DRUG: epirubicin hydrochloride|DRUG: carboplatin|PROCEDURE: therapeutic conventional surgery|DRUG: paclitaxel|OTHER: laboratory biomarker analysis|OTHER: quality-of-life assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Implementing Technology Enhanced Real Time Action Observation Therapy in Persons With Chronic Stroke
Status: COMPLETED
Conditions: Chronic Stroke|Hemiplegia|Hemiparesis|Paralysis
Interventions: DEVICE: Real-time action observation with augmented Kinect
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Effect of Non-estrogenic Pollen Extract PCC-100 on Hot Flushes
Status: COMPLETED
Conditions: Breast Cancer|Hot Flashes|Postmenopausal Symptoms
Interventions: DIETARY_SUPPLEMENT: non-estrogenic pollen extract PCC-100|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dose Escalation Study of IL-7 and Bi-therapy in HCV Patients Resistant After 12 Weeks of Bi-therapy (ECLIPSE 1)
Status: COMPLETED
Conditions: Hepatitis C
Interventions: DRUG: Interleukin-7
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Supplementation of Antidepressants With Fish Oil to Improve Time to Clinical Response
Status: WITHDRAWN
Conditions: Major Depressive Disorder
Interventions: DIETARY_SUPPLEMENT: Omega-3 fatty acid|DRUG: Bovine gelatin capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Pharmacokinetics and Safety of IDV/r With NRTIs in HIV/TB Co-infected Patients Receiving Rifampicin
Status: COMPLETED
Conditions: HIV Infections|Tuberculosis
Interventions: DRUG: indinavir/ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GLAD-AML - Glasdegib (Pf-04449913) With Two Standard Decitabine Regimens for Older Patients With Poor-risk Acute Myeloid Leukemia
Status: TERMINATED
Conditions: ACUTE MYELOID LEUKEMIA
Interventions: DRUG: Glasdegib|DRUG: Decitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Virtual Reality Effects on Food Intake Game to Decrease Food Intake
Status: COMPLETED
Conditions: Food Intake
Interventions: OTHER: Real Food|OTHER: Real Nonfood|OTHER: Virtual reality Food|OTHER: Virtual reality Nonfood|OTHER: Virtual reality Food Branded
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Self-Administered Nitrous Oxide (SANO) During Transrectal Prostate Biopsy to Reduce Patient Anxiety and Pain
Status: COMPLETED
Conditions: Prostate Disease|Malignancy|Benign Prostatic Hyperplasia|Prostate Cancer|Prostate Adenocarcinoma|Anxiety and Fear|Pain
Interventions: DRUG: Self-Administered Nitrous Oxide|OTHER: Oxygen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pharmacokinetic (PK) Study of Twice Daily vs Once Daily Lamivudine (3TC) and Abacavir (ABC) as Part of Combination Antiretroviral Therapy (ART) in HIV Infected Children
Status: COMPLETED
Conditions: HIV Infection
Interventions: DRUG: ABC Twice Daily|DRUG: ABC Once Daily|DRUG: 3TC Once Daily|DRUG: 3TC Twice Daily
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability of SPD503 and Psychostimulants in Children and Adolescents Aged 6-17 With Attention-Deficit/Hyperactivity Disorder (ADHD)
Status: COMPLETED
Conditions: Attention Deficit Disorder With Hyperactivity
Interventions: DRUG: Methylphenidate + SPD503 (Guanfacine hydrochloride)|DRUG: Amphetamine + SPD503
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Paclitaxel Liposome and S-1 as First-line Therapy in \ Advanced Pancreatic Cancer Patients
Status: UNKNOWN
Conditions: Advanced Pancreatic Cancer
Interventions: DRUG: Paclitaxel liposome|DRUG: S-1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Smoking Cessation Advice Combined With Spirometric Results in Adult Smokers (ESPITAP)
Status: COMPLETED
Conditions: Smoking Cessation
Interventions: BEHAVIORAL: Smoking cessation advice|BEHAVIORAL: Spirometry and smoking cessation advice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Integrated Care (iCare) at Mount Sinai to Improve Substance Use Diagnosis and Treatment Practices in HIV Clinic Settings
Status: COMPLETED
Conditions: Substance Abuse
Interventions: BEHAVIORAL: Patient-administered screening tool|BEHAVIORAL: Patient health navigator-administered screening tool|BEHAVIORAL: Patient health navigator-assisted linkage to treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of an Cognitive Behaviour Therapy for Internalised Stigma Intervention for Inpatients With Psychosis
Status: UNKNOWN
Conditions: Cognitive Behaviour Therapy for Internalised Stigma|Psychoeducation
Interventions: OTHER: Cognitive Behaviour Therapy|OTHER: Psychoeducation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Use of High Concentration Hyaluronic Acid (HA) Transfer Medium in Repeated Implantation Failure (RIF) Patients
Status: RECRUITING
Conditions: IVF|Embryo Loss|Miscarriage, Recurrent
Interventions: DRUG: EmbryoGlue®, Vitrolife|DRUG: Conventional Transfer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study Evaluating Sulforaphane in Atypical Nevi-Precursor Lesions
Status: COMPLETED
Conditions: Atypical Nevi|Melanoma
Interventions: DRUG: broccoli sprout extract - sulforaphane (BSE-SFN)|DRUG: broccoli sprout extract - sulforaphane (BSE-SFN)|DRUG: broccoli sprout extract - sulforaphane (BSE-SFN)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Vestibular Rehabilitation in Patients With Vestibular Migraine
Status: COMPLETED
Conditions: Vestibular Migraine|Vestibular Disorder|Migraine Variant
Interventions: OTHER: Control|BEHAVIORAL: Vestibular Rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intervention to Reduce Stress in 0-5 Year Olds With Burns
Status: COMPLETED
Conditions: Stress, Psychological|Post-Traumatic Stress Disorder|Major Injury
Interventions: BEHAVIORAL: DEF-only|BEHAVIORAL: DEF + COPE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Treatment of Insomnia in Patients With Parkinson's Disease: A Multi-site, Placebo-controlled Study of Eszopiclone
Status: COMPLETED
Conditions: Parkinson's Disease|Insomnia
Interventions: DRUG: eszopiclone|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT