pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Double Rewire Versus Double Kissing Crush Stenting Technique in Left Main Bifurcation Lesions
Status: UNKNOWN
Conditions: Coronary Artery Disease
Interventions: PROCEDURE: DK crush|PROCEDURE: DR crush
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anterior Knee Pain in Mobile Bearing Versus Fixed Bearing in TKA
Status: COMPLETED
Conditions: Joint Diseases|Arthritis Knee|Arthroplasty Complications
Interventions: PROCEDURE: Total knee arthroplasty with a Mobile Bearing system.|PROCEDURE: Total knee arthroplasty with a Fixed Bearing system.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: HPI in Older Patients Undergoing Major Gastrointestinal Surgery
Status: COMPLETED
Conditions: the Severity and Duration of Intraoperative Hypotension
Interventions: DEVICE: hypotension prediction index guided|OTHER: without hypotesion prediction index guided
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Online MBCT vs HEP for Depressive Symptoms in Older Adults: RCT
Status: RECRUITING
Conditions: Older Age; Depression
Interventions: BEHAVIORAL: Online Mindfulness Based Cognitive Therapy or Health Education Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: First-In-Human Study in Subjects With Advanced or Metastatic Solid Malignant Tumors
Status: RECRUITING
Conditions: Advanced Solid Tumors|Metastatic Solid Tumors
Interventions: DRUG: JSKN003
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Multiple Injections of (PRF) on The Rate of Canine Retraction
Status: RECRUITING
Conditions: Platelet-Rich Fibrin|Acceleration|Orthodontics
Interventions: PROCEDURE: Injectable platelet rich fibrin (i-PRF): in acceleration of orthodontic tooth movement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vinblastine and Temsirolimus in Pediatrics With Recurrent or Refractory Lymphoma or Solid Tumours Including CNS Tumours
Status: COMPLETED
Conditions: Recurrent Lymphoma|Refractory Lymphoma|Solid Tumours|Central Nervous System
Interventions: DRUG: Vinblastine|DRUG: Temsirolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: S9700 Combination Chemotherapy in Treating Patients With Stage II or Stage III Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DRUG: dipyridamole|DRUG: fluorouracil|DRUG: leucovorin calcium|DRUG: mitomycin C
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized Controlled Trial Evaluating the Efficacy of Intralesional Triamcinolone in Hidradenitis Suppurativa.
Status: COMPLETED
Conditions: Hidradenitis Suppurativa
Interventions: DRUG: Triamcinolone Acetonide 10mg/mL|DRUG: Triamcinolone Acetonide 40mg/mL|DRUG: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Adjusting Challenge-Skill Balance to Improve the Elderly's Quality of Life
Status: COMPLETED
Conditions: Elderly
Interventions: OTHER: Adjusted the challenge-skill balance|OTHER: Non-adjusted the challenge-skill balance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Second Line Therapy for the Cure of Helicobacter Pylori (H. Pylori) Infection
Status: UNKNOWN
Conditions: Helicobacter Infections|Gastritis|Gastric Ulcer|Duodenal Ulcer
Interventions: DRUG: rabeprazole, amoxicillin, clarithromycin, metronidazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Prediction of Pathology Response of Chemoradiotherapy With FLT PET
Status: TERMINATED
Conditions: Esophageal Cancer|Non-small Cell Lung Cancer
Interventions: DRUG: Fluoro-L-Thymidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Colonisation Efficacy of Oral Probiotic Fast Melt Powder
Status: UNKNOWN
Conditions: Microbial Colonization
Interventions: DIETARY_SUPPLEMENT: Probiotic Streptococcus salivarius K12 Fast Melt Powder 1 Billion colony forming units /g)|DIETARY_SUPPLEMENT: Probiotic Streptococcus salivarius K12 Fast Melt Powder 100 Million colony forming units /g)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Application of Remote Ischemic Preconditioning in Patients Undergoing Open Heart Surgeries
Status: UNKNOWN
Conditions: Coronary Artery Disease|Valvular Heart Disease
Interventions: PROCEDURE: IRPC, Remote preconditioning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Reach Out: Emergency Department-Initiated Hypertension Behavioral Intervention Connecting Multiple Health Systems
Status: COMPLETED
Conditions: Hypertension
Interventions: BEHAVIORAL: Healthy Behavior Texts|BEHAVIORAL: No healthy behavior texts|BEHAVIORAL: BP Monitoring Daily Via Text Messaging|BEHAVIORAL: BP Monitoring Weekly Via Text Messaging|BEHAVIORAL: Physician appointment and transportation scheduling|BEHAVIORAL: No physician appointment and transportation scheduling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Suprascapular Nerve Block Guided by Ultrasound
Status: COMPLETED
Conditions: Rotator Cuff Syndrome
Interventions: PROCEDURE: Lidocaine|PROCEDURE: Saline solution|OTHER: Homemade exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of MgSO4 as Tocolytics Compared to Ritodrine in Preterm Labor
Status: COMPLETED
Conditions: Preterm Labor
Interventions: DRUG: MgSO4|DRUG: YTP(Ritodrine)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment With Romosozumab Versus Denosumab to Improve Bone Mineral Density and Architecture in Subacute SCI
Status: ACTIVE_NOT_RECRUITING
Conditions: Osteoporosis|Spinal Cord Injuries
Interventions: DRUG: Romosozumab|DRUG: Denosumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparison Between Propofol-remifentanil Total Intravenous Anesthesia and Desflurane-remifentanil Balanced Anesthesia With Regard to Post-anesthetic Functional Recovery Measured With QoR-40
Status: COMPLETED
Conditions: Thyroid Operation Under General Anesthesia
Interventions: DRUG: desflurane group|DRUG: TIVA group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Safety, Tolerability, and Immunogenicity of ALFQ in a HIV Vaccine Containing A244 and B.65321 in Healthy Adults
Status: RECRUITING
Conditions: Human Immunodeficiency Virus (HIV)|AIDS Virus
Interventions: BIOLOGICAL: A244|BIOLOGICAL: B.63521|BIOLOGICAL: 50μg ALFQ|BIOLOGICAL: 100μg ALFQ|BIOLOGICAL: 200μg ALFQ
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Intrapleural Bevacizumab After Pleural Drainage in the Context of Breast Cancer
Status: TERMINATED
Conditions: Pleural Effusion, Malignant|Breast Cancer
Interventions: DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of the Monoclonal Antibody VYD222 in Healthy Adult Participants
Status: COMPLETED
Conditions: COVID-19
Interventions: DRUG: VYD222|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Pain After Laparoscopic Cholecystectomy
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: Desflurane|DRUG: Sevoflurane|DRUG: Isoflurane|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Recombinant Human Endostatin in Non-Small Cell Lung Cancer With Leptomeningeal Metastasis
Status: UNKNOWN
Conditions: Leptomeningeal Metastasis
Interventions: DRUG: Recombinant Human Endostatin|DRUG: intrathcal methotrexate|DRUG: Targeted drugs for non-small cell lung cancer
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Heated Intraperitoneal Chemotherapy and Gastrectomy for Gastric Cancer With Positive Peritoneal Cytology
Status: COMPLETED
Conditions: Gastric Adenocarcinoma|Esophagogastric Junction|Gastric Cancer
Interventions: PROCEDURE: Surgery|DRUG: Cisplatin|DRUG: Mitomycin C|DRUG: Sodium Thiosulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 3, Multicenter, Open-label Continuation Study in Moderate to Severe Asthmatic Subjects Who Completed FlutiForm HFA pMDI Study SKY2028-3-005
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: SKP FlutiForm HFA pMDI
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Outpatient Cervical Preparation to Reduce Induction Duration in NTSV Women
Status: WITHDRAWN
Conditions: Cervical Ripening|Outpatient|Patient Satisfaction|Nulliparous|Length of Stay
Interventions: OTHER: Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of 3 Learning Methods to Improve Independent Activities of Daily Living (IADLs) in Alzheimer Disease
Status: UNKNOWN
Conditions: Alzheimer Disease
Interventions: BEHAVIORAL: Errorless Learning|BEHAVIORAL: Modeling|BEHAVIORAL: Trial and Error
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of Exercise Endurance and Lung Hyperinflation in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Aclidinium Bromide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: D-Stress Baltimore: School-based Mindfulness Instruction
Status: COMPLETED
Conditions: Coping|Stress Disorders, Post-Traumatic|Mental Health Wellness 1
Interventions: BEHAVIORAL: Mindfulness Instruction|BEHAVIORAL: Health Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of the Safety, Pharmacodynamics (PD) and Efficacy of KRN23 in Children From 1 to 4 Years Old With X-linked Hypophosphatemia (XLH)
Status: COMPLETED
Conditions: X-Linked Hypophosphatemia
Interventions: BIOLOGICAL: Burosumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of CD19 Targeted CAR T Cell Therapy in Pediatric Patients With Relapsed or Refractory B Cell Acute Lymphoblastic Leukaemia (B ALL) and Aggressive Mature B-cell Non-Hodgkin Lymphoma (B NHL)
Status: RECRUITING
Conditions: Relapsed or Refractory B Cell Acute Lymphoblastic Leukemia|Relapsed or Refractory B Cell Non-Hodgkin Lymphoma
Interventions: BIOLOGICAL: AUTO1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ibrutinib in Previously Untreated Binet Stage A Chronic Lymphocytic Leukemia With Risk of Disease Progression
Status: COMPLETED
Conditions: Chronic Lymphocytic Leukemia
Interventions: DRUG: Ibrutinib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of T-APCs Following CAR T Cell Immunotherapy for CD19+ Leukemia
Status: ACTIVE_NOT_RECRUITING
Conditions: CD 19+ Acute Leukemia
Interventions: BIOLOGICAL: T-cell Antigen Presenting Cells expressing truncated CD19 (T-APC)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nitric Oxide Releasing Solutions to Prevent and Treat Mild/Moderate COVID-19 Infection
Status: COMPLETED
Conditions: Corona Virus Infection
Interventions: DRUG: NORS (Nitric Oxide Releasing Solution)|DRUG: NORS (Nitric Oxide Releasing Solution)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: US Guided GNB vs Saline Injection for TKA
Status: TERMINATED
Conditions: Postoperative Pain|Total Knee Arthroplasty|Nerve Block
Interventions: DRUG: bupivacaine|DRUG: saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Corneal Oxygen Uptake With Apioc Contact Lenses
Status: COMPLETED
Conditions: Contact Lens-Induced Corneal Disorder of Both Eyes (Diagnosis)
Interventions: DEVICE: Apioc Contact Lens
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Pulsed Electromagnetic Field (PEMF) Systems to Promote the Maintenance of Bone and Muscle
Status: UNKNOWN
Conditions: Muscle Loss Post Anterior Cruciate Ligament Reconstruction
Interventions: DEVICE: Pulsed Electromagnetic Field Therapy|DEVICE: Sham Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study of TQB2450 Injection Combined With Anlotinib Hydrochloride Capsules Versus Paclitaxel as Weekly Treatment of Relapsed Platinum-resistant Ovarian Cancer
Status: RECRUITING
Conditions: Recurrent Platinum-resistant Ovarian Cancer
Interventions: DRUG: Anlotinib Hydrochloride Capsules|DRUG: Paclitaxel injection|DRUG: TQB2450 injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Soluble Corn Fiber Supplementation for Asthma
Status: COMPLETED
Conditions: Asthma in Children
Interventions: DRUG: Soluble Corn Fiber
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cognitive Remediation in Schizophrenia: Efficacy and Role of Neuroplasticity in "Top-down" and "Bottom-up" Mechanisms
Status: RECRUITING
Conditions: Schizophrenia
Interventions: BEHAVIORAL: Cognitive Remediation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Oral Lactulose Versus Polyethylene Glycol for Bowel Preparation in Low-risk Patients
Status: COMPLETED
Conditions: Colonic Neoplasms
Interventions: DRUG: Lactulose oral solution|DRUG: PEG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Treatment Pause Versus Treatment Continuation in IMDC Good or Intermediate Risk With Only One Adverse Prognostic Factor in mRCC Patients With an Objective Response at 12 Months of Treatment With PD1/ PDL1 ICIs + VEGFR-Tyrosine Kinase Inhibitors
Status: RECRUITING
Conditions: Metastatic Renal Cell Carcinoma|Good or Only One Adverse Prognostic Factor Intermediate Risk Per IMDC Score
Interventions: DRUG: Combination PD-1/PD-L1 ICI + VEGFR-TKI|OTHER: Treatment pause
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Evaluate the Effect of Multiple Doses of Itraconazole on the Pharmacokinetics of BV100
Status: COMPLETED
Conditions: Bacterial Infections
Interventions: DRUG: BV100 (300 mg)|DRUG: Itraconazole 200 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Efficacy of Micardis® (Telmisartan) and Valsartan in Patients With Mild-to-moderate Hypertension After Missing One Dose Using Ambulatory Blood Pressure Monitoring
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Telmisartan|DRUG: Valsartan|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Combination of Plants in Anxiety-related Sleep Disorders: Randomized Trial Versus Placebo
Status: COMPLETED
Conditions: Sleep Troubles Associated With Anxiety
Interventions: DIETARY_SUPPLEMENT: Noctesia|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hand Therapy or Not Following Collagenase Treatment for Dupuytren's Contracture?
Status: COMPLETED
Conditions: Dupuytren Disease of Palm and Finger, With Contracture
Interventions: OTHER: Hand therapy MCPJ affected|OTHER: Hand therapy PIPJ affected
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Non-elastic Compression Garment Therapy Versus Control for Deep Vein Thrombosis
Status: RECRUITING
Conditions: Deep Vein Thrombosis|Post Thrombotic Syndrome
Interventions: DEVICE: Circaid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Supplementation With Two Different Doses of Vitamin D on Bone Mineral Density, Vitamin D Levels and Hand Grip Strength in Children With Diabetes Mellitus Type 1
Status: COMPLETED
Conditions: Diabetes Mellitus Type 1
Interventions: DRUG: Vitamin D3|DRUG: Vitamin D3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Brain Vascular and Neurocognitive Health
Status: RECRUITING
Conditions: Cognitive Decline|Cognitive Dysfunction|Alzheimer Disease|Vascular Disease, Peripheral
Interventions: DEVICE: Transcranial Photobiomodulation|DEVICE: Transcranial Photobiomodulation helmet (Neuradiant 1070 Plus) with no light administered
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Assess Safety, Tolerability, Pharmacokinetics (PK), Immunogenicity, and Pharmacodynamics (PD) of Intravenous Infusions of E2814 in Healthy Participants
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: E2814|DRUG: E2814-matched placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: The Effects of Mental Practice Combined With Proprioceptive Neuromuscular Facilitation on Muscle Strength of Upper Limb and Hand Grip
Status: COMPLETED
Conditions: Motor Activity|Physical Activity|Neuromuscu
Interventions: PROCEDURE: PNF|PROCEDURE: PNFMP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study to Compare the Overall Survival of Patients Receiving INGN 201 (Study Drug) With Patients Receiving Methotrexate
Status: UNKNOWN
Conditions: Carcinoma, Squamous Cell
Interventions: GENETIC: INGN 201
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Tolerance and Safety of a Peptide-based Enteral Formula With Partially Hydrolyzed Guar Gum (PHGG)
Status: COMPLETED
Conditions: Enteral Nutrition
Interventions: OTHER: Enteral Formula With (PHGG)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: One Year Clinical Evaluation of Milled BioHPP Polyetheretherketone (PEEK)-Based Versus Metal Ceramic Single Crowns
Status: UNKNOWN
Conditions: Single Posterior Crowns|Badly Decayed Teeth, Teeth Restored With Large Filling Restorations or Endodontically Treated Teeth|Malformed Teeth, Malposed Teeth (Tilted, Over-erupted, Rotated, Etc.) or Spacing Between Posterior Teeth
Interventions: OTHER: BioHPP PEEK-based single posterior crowns|OTHER: Metal ceramic single posterior crowns
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use of a Smartphone Application (App) to Assist a Cognitive-Behavioral Smoking Cessation Treatment
Status: COMPLETED
Conditions: Smoking
Interventions: BEHAVIORAL: Cognitive-behavioral treatment to quit smoking along with an App with active therapeutic components|BEHAVIORAL: Cognitive-behavioral treatment to quit smoking along with a control App
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Various Combinations of BiDil Capsules and BiDil Tablets in Healthy Human Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Isosorbide dinitrate / hydralazine capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparing Telephone Symptom Monitoring Interventions for Managing Symptoms and Psychological Distress During Oral Anti-Cancer Treatment
Status: RECRUITING
Conditions: Hematopoietic and Lymphoid System Neoplasm|Malignant Solid Neoplasm
Interventions: OTHER: Counseling|BEHAVIORAL: Health Education|OTHER: Interview|OTHER: Medical Chart Review|OTHER: Monitoring|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Radiolabeled Monoclonal Antibody in Treating Patients With Previously Treated Large Cell Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: RADIATION: iodine I 131 monoclonal antibody Lym-1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral Dydrogesterone vs. Micronized Vaginal Progesterone for Luteal Phase Support in Frozen-thawed Embryo Transfer Cycles
Status: UNKNOWN
Conditions: Infertility, Female|Infertility, Male|Embryo Transfer|Fertilization in Vitro|Drug Effect|Reproductive Techniques, Assisted|Progesterone|Dydrogesterone
Interventions: DRUG: Dydrogesterone 10 MG Oral Tablet|DRUG: Progesterone Vaginal Gel [Crinone]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sildenafil for Swimming-Induced Pulmonary Edema (SIPE) Prevention
Status: COMPLETED
Conditions: Edema, Pulmonary|Immersion|Diving
Interventions: DRUG: Sildenafil Citrate|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Optimal Site of Administration for Continuous Wound Infusion After Cesarean Section
Status: COMPLETED
Conditions: Cesarean Section
Interventions: PROCEDURE: Continuous wound infusion|PROCEDURE: Continuous wound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Does Ultrasound Guidance Improve Time to Perform a Spinal or Number of Attempts in Obese Patients?
Status: COMPLETED
Conditions: Spinal Anesthesia Administration
Interventions: PROCEDURE: Ultrasound guidance|PROCEDURE: Palpation of Tuffier's line|PROCEDURE: Spinal anesthetic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Use Of Virtual Reality To Reduce Anxiety And Pain During Repair Of Perineal Laceration And Episiotomy
Status: RECRUITING
Conditions: Perineum; Injury|Episiotomy Wound|Anxiety
Interventions: DEVICE: Virtual Reality for Anxiety Reduction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Clinical Trial to Evaluate the Initial Safety and Efficacy of Repetitive BBB (Blood Brain Barrier) Disruption Using High Intensity Focused Ultrasound 'ExAblate 4000 Type 2.1' in Patients With Alzheimer's Disease
Status: NOT_YET_RECRUITING
Conditions: Alzheimer Disease
Interventions: DEVICE: ExAblate 4000 Type 2.1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vaccine Therapy With Bevacizumab Versus Bevacizumab Alone in Treating Patients With Recurrent Glioblastoma Multiforme That Can Be Removed by Surgery
Status: TERMINATED
Conditions: Recurrent Glioblastoma|Recurrent Adult Brain Tumor|Gliosarcoma
Interventions: BIOLOGICAL: HSPPC-96|DRUG: bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study on OsseoSpeed™ Implants Replacing 2-5 Teeth in the Posterior Upper Jaw, Restored With Provisional Teeth Attached 6-7 Weeks Later
Status: COMPLETED
Conditions: Jaw, Edentulous, Partially
Interventions: DEVICE: OsseoSpeed™
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ambulatory Rehabilitation Program in Patients With Degenerative Rupture of the Rotator Cuff Tendons of the Shoulder
Status: UNKNOWN
Conditions: Shoulder Pain
Interventions: PROCEDURE: Ambulatory rehabilitation program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Trial of Oxytocin Alone Versus Oxytocin and Propranolol for the Treatment of Abnormal Labor
Status: WITHDRAWN
Conditions: Dysfunctional Labor
Interventions: DRUG: Propranolol|OTHER: IV Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Allogeneic Mesenchymal Bone Marrow Cells in Subjects With ST Segment Elevation Myocardial Infarction (STEMI)
Status: WITHDRAWN
Conditions: ST Segment Elevation Myocardial Infarction (STEMI)|Allogeneic Mesenchymal Bone Marrow Cells
Interventions: BIOLOGICAL: Stem cells
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hartmann's Versus Primary Anastomosis in Left-sided Colon Perforation
Status: COMPLETED
Conditions: Surgery|Diverticulitis|Neoplasms|Postoperative Complications
Interventions: PROCEDURE: Hartmann's operation|PROCEDURE: Primary anastomosis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Concomitant Use of Clopidogrel With Atorvastatin or Rosuvastatin in Patients With Minor Stroke or TIA
Status: RECRUITING
Conditions: Ischemic Stroke
Interventions: DRUG: Atorvastatin 40mg|DRUG: Rosuvastatin 20mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Amifostine in Treating Patients With Stage II or Stage III Non-small Cell Lung Cancer
Status: COMPLETED
Conditions: Drug/Agent Toxicity by Tissue/Organ|Lung Cancer|Oral Complications|Radiation Toxicity
Interventions: BIOLOGICAL: filgrastim|DRUG: amifostine trihydrate|DRUG: carboplatin|DRUG: paclitaxel|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: High Versus Low Blood-Pressure Target in the Post Operative Care of Liver Transplantation A Randomized, Controled, Open and Unicentric Trial.
Status: COMPLETED
Conditions: Liver Transplant; Complications
Interventions: OTHER: Usual Care + High Target of Mean Arterial Pressure|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study in Patients With Amyotrophic Lateral Sclerosis (ALS)
Status: COMPLETED
Conditions: Amyotrophic Lateral Sclerosis (ALS)
Interventions: DRUG: E0302 (mecobalamin)|DRUG: E0302 (mecobalamin)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: REgistRy BRAnch goRE EndopRosthEsis
Status: NOT_YET_RECRUITING
Conditions: Aortic Aneurysm, Thoracic|Aortic Dissection
Interventions: DEVICE: GORE TAG Thoracic Branch Endoprosthesis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Randomized, Pharmacodynamic Comparison of Low Dose Ticagrelor to Clopidogrel in Patients With Prior Myocardial Infarction
Status: COMPLETED
Conditions: Myocardial Infarction|Diabetes Mellitus|Renal Disease|Coronary Artery Disease
Interventions: DRUG: Ticagrelor|DRUG: Clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Emergency Use of Donor Lymphocytes in Treating Patients Who Have Undergone Donor Stem Cell Transplant and Have Cytomegalovirus Infections
Status: UNKNOWN
Conditions: Cancer
Interventions: BIOLOGICAL: cytomegalovirus IE-1-specific cytotoxic T lymphocytes|BIOLOGICAL: cytomegalovirus pp65-specific cytotoxic T lymphocytes|BIOLOGICAL: therapeutic allogeneic lymphocytes|GENETIC: polymerase chain reaction|OTHER: flow cytometry|OTHER: immunological diagnostic method|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Xenogeneic Collagen Matrix on the Peri-implant Tissues of Immediate Implants.
Status: UNKNOWN
Conditions: Xenograft Model
Interventions: DEVICE: Xenogenic collagen matrix|DEVICE: Autogenous connective tissue graft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Melasma Using Q-switched Nd: YAG Laser and Fractional CO2 Laser Separately and in Combination
Status: COMPLETED
Conditions: Melasma
Interventions: DEVICE: Q switched Nd YAG laser|DEVICE: Fractional CO2 laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of BI 10773 in Type II Diabetes Patients With Different Degrees of Renal Impairment
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: BI 10773|DRUG: BI 10773|DRUG: BI 10773|DRUG: BI 10773|DRUG: BI 10773
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pomalidomide and Dexamethasone (PDex) in AL Amyloidosis
Status: COMPLETED
Conditions: Primary Amyloidosis of Light Chain Type
Interventions: DRUG: Pomalidomide and Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study of Fluconazole Plus Flucytosine for the Treatment of AIDS Patients With Acute Cryptococcal Meningitis.
Status: COMPLETED
Conditions: Meningitis, Cryptococcal|HIV Infections
Interventions: DRUG: Flucytosine|DRUG: Fluconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Peripheral Nerve Stimulation to Improve Upper Extremity Function After Severe Stroke
Status: TERMINATED
Conditions: Stroke
Interventions: DEVICE: Peripheral nerve stimulation (PNS)|BEHAVIORAL: Intensive upper extremity motor training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: STARchy Staples: a Randomised Controlled Trial on Cardiometabolic Health
Status: RECRUITING
Conditions: Cardiometabolic Health
Interventions: DIETARY_SUPPLEMENT: Habitual potato consumption|DIETARY_SUPPLEMENT: Habitual non-nutrient-dense staple consumption
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of Brexucabtagene Autoleucel (KTE-X19) in Participants With Relapsed/Refractory Mantle Cell Lymphoma (Cohort 1 and Cohort 2)
Status: COMPLETED
Conditions: Relapsed/Refractory Mantle Cell Lymphoma
Interventions: BIOLOGICAL: brexucabtagene autoleucel|DRUG: Cyclophosphamide|DRUG: Fludarabine|DRUG: Axicabtagene Ciloleucel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exercise Timing and the Circadian Clock in Individuals With Type 2 Diabetes and Those at Risk
Status: NOT_YET_RECRUITING
Conditions: Diabetes Mellitus, Type 2
Interventions: BEHAVIORAL: HIIT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Simvastatin as a Treatment for Pulmonary Hypertension
Status: COMPLETED
Conditions: Pulmonary Hypertension
Interventions: DRUG: Simvastatin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Single Centre Blinded Randomized Controlled Trial Evaluating the Effectiveness of Two Pelvic Support Garments
Status: COMPLETED
Conditions: Pelvic Pain|Symphysis Pubis Dysfunction
Interventions: DEVICE: Customised Dynamic Elastomeric fabric Orthoses|DEVICE: Serola Sacroiliac Belt
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Patient-centered Communication Tool (UR-GOAL) for Older Patients With Acute Myeloid Leukemia, Their Caregivers, and Their Oncologists
Status: COMPLETED
Conditions: Acute Myeloid Leukemia
Interventions: BEHAVIORAL: Behavioral: UR-GOAL communication tool
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Electrical Stimulation After Total Knee Arthroplasty
Status: UNKNOWN
Conditions: Total Knee Arthroplasty|Osteoarthritis
Interventions: PROCEDURE: Neuromuscular electrical stimulation|PROCEDURE: Voluntary exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Phase 1 PK Study of XOMA 3AB
Status: COMPLETED
Conditions: Botulism
Interventions: DRUG: XOMA 3AB|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Does Modified Ultrafiltration Improves Inflammatory Response and Cardiopulmonary Function After CABG Procedures?
Status: COMPLETED
Conditions: Coronary Artery Disease|Cardiac Surgical Procedures
Interventions: PROCEDURE: Modified Ultrafiltration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Adjuvant Dabrafenib (GSK2118436) in Patients With Surgically Resected AJCC Stage IIIC Melanoma Characterized by a BRAFV600E/K Mutation
Status: COMPLETED
Conditions: Melanoma
Interventions: DRUG: Dabrafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Whole-body Vibration Exercise in Brain Injury Patients With Minimally Conscious State
Status: UNKNOWN
Conditions: Brain Injuries|Minimally Conscious State
Interventions: DEVICE: Whole body vibration|OTHER: Exersice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Photopheresis Plus Standard Therapy to Treat Chronic Graft-versus-Host Disease
Status: COMPLETED
Conditions: Graft-versus-Host Disease
Interventions: DRUG: Methoxsalen|PROCEDURE: Extracorporeal Photopheresis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Topical Cannabidiol Application and Skin Vascular Reactivity
Status: ENROLLING_BY_INVITATION
Conditions: Effect of Drug
Interventions: BIOLOGICAL: Cannabidiol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Topical CBD for Musculoskeletal Pain
Status: UNKNOWN
Conditions: Pain
Interventions: DRUG: GoodFOR Pain|DRUG: Icy Hot|DRUG: Tiger Balm|DRUG: Bengay|DRUG: CBD Clinic Muscle and Joint Pain Relief Ointment|DRUG: CBD FX CBD Muscle and Joint Cream: Cooling Formula|DRUG: Essential Wholesale Muscle Gel|DRUG: Extract Labs Muscle Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Anlotinib Combined With TQB2450 (PD-L1 Inhibitor) in the Treatment of Advanced Esophageal Squamous Cell Carcinoma(ESCC)
Status: ACTIVE_NOT_RECRUITING
Conditions: Esophageal Squamous Cell Carcinoma
Interventions: DRUG: Anlotinib+TQB2450
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aesthetic Outcome of Running Subcuticular Suture Versus Running Horizontal Mattress Suture Closure of Linear Wounds on the Trunk and Extremities
Status: ACTIVE_NOT_RECRUITING
Conditions: Wound of Skin|Scar
Interventions: OTHER: Suture Closure of Linear Wounds
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: University of North Carolina-Healthwise Partnership Project on Birth Options Decision Aid
Status: COMPLETED
Conditions: Scar; Previous Cesarean Section|Vaginal Birth After Cesarean|Decision Making, Shared
Interventions: OTHER: Decision Aid
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Prospective Clinical Surveillance With Application of Trigger Tools in Critically Ill Patients
Status: COMPLETED
Conditions: Critical Illness
Interventions: OTHER: KDIGO|OTHER: Delta SOFA|COMBINATION_PRODUCT: Hypoglycemia|DRUG: Drug interaction risk D or X|DRUG: Antimicrobial stewardship
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Upper Extremity Aerobic Exercise Training on Exercise Capacity Patients With Chronic Heart Failure
Status: WITHDRAWN
Conditions: Chronic Heart Failure
Interventions: OTHER: Upper extremity aerobic exercise|OTHER: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Enhanced Recovery After Surgery for Total Knee Arthroplasty, Left Colectomy and Hysterectomy
Status: UNKNOWN
Conditions: Surgery|Total Knee Arthroplasty|Colectomy|Hysterectomy
Interventions: PROCEDURE: One year before awareness-raising phase in favour of Enhanced Recovery After Surgery|PROCEDURE: One year after awareness-raising phase in favour of Enhanced Recovery After Surgery|PROCEDURE: No specific program toward improving practices
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Auricular Acupressure : Improves Oxaliplatin-induced Peripheral Neuropathy
Status: UNKNOWN
Conditions: Oxaliplatin-induced Peripheral Neuropathy|Chemotherapy
Interventions: OTHER: auricular acupressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Participatory Design of Electronic Health Record Tools for Problem Solving Therapy
Status: COMPLETED
Conditions: Depression
Interventions: BEHAVIORAL: Problem Solving Therapy as Usual|BEHAVIORAL: Assisted Problem Solving Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Safety and Immunogenicity Study of Rift Valley Fever Vaccine, Inactivated
Status: COMPLETED
Conditions: Rift Valley Fever
Interventions: BIOLOGICAL: Inactivated, Dried (TSI-GSD 200), RVF Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of Single and Multiple SC Doses of ALXN1830 in Healthy Adult Participants
Status: TERMINATED
Conditions: Healthy
Interventions: DRUG: ALXN1830|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Sutezolid
Status: COMPLETED
Conditions: Tuberculosis|Tuberculosis, Pulmonary
Interventions: DRUG: Sutezolid|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Dose Escalation Study Using Collagenase Clostridium Histolyticum in the Treatment of Lipoma
Status: COMPLETED
Conditions: Lipoma
Interventions: DRUG: Collagenase Clostridium Histolyticum
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SensAwake™ Sleep Quality Trial
Status: COMPLETED
Conditions: Sleep Apnea, Obstructive
Interventions: DEVICE: SleepStyle 200 Auto Series with SensAwake|DEVICE: SleepStyle 200 Auto Series with out SensAwake
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Compare CE-Budesonide Nasal Solution & Rhinocort Aqua in an EEC Study of AR
Status: COMPLETED
Conditions: Seasonal Allergic Rhinitis
Interventions: DRUG: Budesonide|DRUG: Placebo|DRUG: Budesonide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study to Evaluate the Clinical Performance and Safety of LiquiBand FIX8® Versus AbsorbaTack™ for Hernia Mesh Fixation and Peritoneal Closure in Groin Hernia Repair
Status: COMPLETED
Conditions: Hernia|Inguinal Hernia|Femoral Hernia|Groin Hernia
Interventions: DEVICE: LiquiBand FIX8®|DEVICE: AbsorbaTack™
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Allogeneic Tumor Cell Vaccination in Patients With Chronic Myeloid Leukemia
Status: WITHDRAWN
Conditions: Chronic Myeloid Leukemia
Interventions: BIOLOGICAL: Allogeneic tumor cell vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Implementation a Data-to-Care Strategy to Improve HIV Continuum Outcomes for Out of Care People Living With HIV (PLWH) in Ukraine
Status: RECRUITING
Conditions: HIV Infections
Interventions: BEHAVIORAL: Data to care|BEHAVIORAL: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Regional Anesthesia in Hip Arthroscopy
Status: WITHDRAWN
Conditions: Femoroacetabular Impingement
Interventions: DRUG: regional anesthesia bupivacaine|DRUG: regional anesthesia placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH