pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Combined Supine/Prone Acquisitions in Stress-First/Stress-Only Myocardial Perfusion Imaging to Reduce Equivocal Results
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DEVICE: Gamma Camera|PROCEDURE: Prone Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of a Propranolol (HEMANGIOL®) and Oral Metronomic Vinorelbine (NAVELBINE®) Combination for Children and Teenagers With Refractory/Relapsing Solid Tumors
Status: UNKNOWN
Conditions: Pediatric Cancer
Interventions: DRUG: administration of a propranolol (HEMANGIOL®) and oral metronomic vinorelbine (NAVELBINE®) combination
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prostate Cancer Diagnosis by Multiparametric Ultrasound (Wholemount)
Status: RECRUITING
Conditions: Prostate Carcinoma
Interventions: DRUG: Perflutren Lipid Microspheres|PROCEDURE: Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Biological Investigations in Active Surveillance (BIAS) IGAR 2008 I 19 in Prostate Cancer Using High Field MRI (3 Tesla), PET, and Biomarkers
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: PROCEDURE: 3T MR Imaging|PROCEDURE: C-Choline PET Scanning|PROCEDURE: Gene Rearrangement
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: The Nitazoxanide Plus Atazanavir for COVID-19 Study
Status: TERMINATED
Conditions: Covid-19
Interventions: DRUG: Nitazoxanide and atazanavir/ritonavir|OTHER: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: What the Nose Knows: Hedonic Capacity, Psychosocial Interventions and Outcomes in Schizophrenia
Status: RECRUITING
Conditions: Schizophrenia
Interventions: BEHAVIORAL: Cognitive Enhancement Therapy|BEHAVIORAL: Social Skills Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Ticagrelor Versus Prasugrel on Coronary Microcirculation in Patients Undergoing Elective Percutaneous Coronary Intervention: Results of the PROtecting MICROcirculation During Coronary Angioplasty (PROMICRO)-3 Randomised Study
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DRUG: Ticagrelor|DRUG: Prasugrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Nasal Mask Ventilation During the Induction of General Anesthesia
Status: COMPLETED
Conditions: Mechanical Ventilation Complication|Upper Airway Obstruction
Interventions: PROCEDURE: nasal mask|PROCEDURE: full face mask
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Registry for Esophageal and Gastroesophageal Junction Cancer
Status: RECRUITING
Conditions: Gastroesophageal-junction Cancer|Esophageal Cancer
Interventions: OTHER: EORTC QLQ-C30 questionnaire|OTHER: QLQ-OGS25 questionnaire
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Use of a Dietary Supplement to Support Digestive Health in Children With Chronic Diarrhea
Status: UNKNOWN
Conditions: Antibiotic-associated Diarrhea
Interventions: DIETARY_SUPPLEMENT: polyphenol supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: BIP ETT Clinical Tolerability, Safety and Performance Study
Status: COMPLETED
Conditions: Endotracheal Intubation During Surgery|Hospital Acquired Infections
Interventions: DEVICE: BIP ETT (Bactiguard)|PROCEDURE: Standard ETT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study to Determine the Safety and Preliminary Efficacy of CC-1088 in the Treatment of Myelodysplastic Syndromes
Status: COMPLETED
Conditions: Myelodysplastic Syndrome
Interventions: DRUG: CC-1088
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RCT of At-Home tDCS for Depression in Pregnancy
Status: RECRUITING
Conditions: Major Depression|Pregnancy|Postpartum Depression
Interventions: DEVICE: active tDCS|OTHER: workbook|DEVICE: sham tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Safety of Contraloid Acetate in Patients With Mild Cognitive Impairment Due to Alzheimer's Disease
Status: COMPLETED
Conditions: Mild Cognitive Impairment Due to Alzheimer's Disease
Interventions: DRUG: Contraloid acetate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Oglemilast for the Treatment of Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Oglemilast|DRUG: Placebo then Oglemilast
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of Galcanezumab (LY2951742) in Participants 6 to 17 Years of Age With Episodic Migraine
Status: RECRUITING
Conditions: Episodic Migraine
Interventions: DRUG: Galcanezumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of PR Oxycodone and of Levodopa, vs Placebo, on Central Neuropathic Pain in Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: DRUG: PR Oxycodone|DRUG: Levodopa|DRUG: Oxycodone Placebo|DRUG: Levodopa placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cheeks Appearance as a Novel Predictor of Obstructive Sleep Apnea The CASA Score Study
Status: COMPLETED
Conditions: Obstructive Sleep Apnea|Breathing, Sleep-Disordered|Muscle Weakness|Muscle Disorder|Face|Swallowing Disorder
Interventions: DIAGNOSTIC_TEST: CASA score protocol to Non-obstructive sleep apnea Group|DIAGNOSTIC_TEST: CASA score protocol to Mild obstructive sleep apnea Group|DIAGNOSTIC_TEST: CASA score protocol to Moderate obstructive sleep apnea Group|DIAGNOSTIC_TEST: CASA score protocol to Severe obstructive sleep apnea Group
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: LEO 90100 Compared With Calcipotriol Plus Betamethasone Dipropionate Ointment, LEO 90100 Vehicle and Ointment Vehicle in Subjects With Psoriasis Vulgaris
Status: COMPLETED
Conditions: Psoriasis Vulgaris
Interventions: DRUG: LEO 90100|DRUG: Betamethasone plus calcipotriol|DRUG: Ointment vehicle|DRUG: LEO 90100 vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Viral Kinetics of Treatment With Peginterferon Alpha-2a, Ribavirin and Epoetin β in Patients Coinfected HCV/HIV
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Peginterferon alfa-2a, Ribavirin, epoetin-β|DRUG: Peginterferon alfa-2a + Ribavirin for 12 weeks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ischemic Conditioning to Promote Microvascular Resiliency in Frail Individuals
Status: RECRUITING
Conditions: Aging|Fragility|Endothelial Dysfunction
Interventions: OTHER: Ischemic Conditioning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nasal Iodine Swab Versus Oral Antibiotic to Prevent Surgical Site Infection After Undergoing Mohs Micrographic Surgery
Status: NOT_YET_RECRUITING
Conditions: Skin Cancer|Skin Cancer Face|Malignant Cutaneous Adnexal Neoplasm
Interventions: OTHER: Povidone-Iodine Swabs|DIAGNOSTIC_TEST: Staphylococcus nasal swab|DRUG: Antibiotic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Donor Peripheral Stem Cell or Bone Marrow Transplant in Treating Patients With Relapsed or Refractory Metastatic Kidney Cancer
Status: COMPLETED
Conditions: Kidney Cancer
Interventions: BIOLOGICAL: anti-thymocyte globulin|BIOLOGICAL: graft-versus-tumor induction therapy|BIOLOGICAL: therapeutic allogeneic lymphocytes|DRUG: cyclophosphamide|DRUG: fludarabine phosphate|DRUG: mycophenolate mofetil|DRUG: tacrolimus|PROCEDURE: allogeneic bone marrow transplantation|PROCEDURE: peripheral blood stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Record Voxel Rate Nonlinear Optical Microscope to Unravel Brain Connectome and Signaling-Establish Reliably Electrophysiological Readouts From Human-induced Pluripotent Stem Cells (hiPSCs)-Derived Cerebral Organoids and Surgically Dissected Human Live Brains
Status: RECRUITING
Conditions: Brain Diseases|Brain Tumor
Interventions: DEVICE: Electrophysiological system|DEVICE: Multiphoton microscope
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: VO2peak and Exercise Efficiency in Upper-body Poling
Status: COMPLETED
Conditions: Spinal Cord Injuries
Interventions: DIAGNOSTIC_TEST: upper-body double-poling|DIAGNOSTIC_TEST: arm crank ergometry
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Compare the Efficacy of Nivolumab and Relatlimab Plus Chemotherapy vs Pembrolizumab Plus Chemotherapy for Stage IV/Recurrent Non-squamous Non-small Cell Lung Cancer With PD-L1 1-49%
Status: NOT_YET_RECRUITING
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: Nivolumab|DRUG: Relatlimab|DRUG: Pembrolizumab|DRUG: Carboplatin|DRUG: Pemetrexed|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: LIFSCREEN : Evaluation of Whole Body MRI for Early Detection of Cancers in Subjects With P53 Mutation (Li-Fraumeni Syndrome)
Status: COMPLETED
Conditions: Li Fraumeni Syndrome
Interventions: OTHER: whole body MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Heated Circuit for One-lung Ventilation
Status: UNKNOWN
Conditions: One-lung Ventilation|Oxygenation|Temperature
Interventions: DEVICE: Heated and humidified breathing circuit on|DEVICE: Heated and humidified breathing circuit off
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phase 2b Evaluation of Efficacy and Safety of AR882 in Gout Patients
Status: COMPLETED
Conditions: Gout|Arthritis, Gouty|Hyperuricemia|Gout Chronic
Interventions: DRUG: AR882 Dose 1|DRUG: AR882 Dose 2|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 1/2a Trial of Pf GAP p52-/p36- Sporozoite Malaria Vaccine
Status: TERMINATED
Conditions: Malaria
Interventions: BIOLOGICAL: p52-/p36- GAP Vaccine|BIOLOGICAL: p52-p36- GAP Vaccine|BIOLOGICAL: p52-/p36- GAP Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Neoadjuvant Immunotherapy in Early Stage Non-small-cell Lung Cancer Presenting as Synchronous Ground-glass Nodules
Status: NOT_YET_RECRUITING
Conditions: Multiple Pulmonary Nodules
Interventions: DRUG: Nivolumab Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Carevive Survivor Care Planning System in Improving Quality of Life in Breast Cancer Survivors
Status: COMPLETED
Conditions: Stage I Breast Cancer|Stage I Cervical Cancer|Stage I Ovarian Cancer|Stage I Uterine Corpus Cancer|Stage IA Breast Cancer|Stage IA Cervical Cancer|Stage IA Ovarian Cancer|Stage IA Uterine Corpus Cancer|Stage IB Breast Cancer|Stage IB Cervical Cancer|Stage IB Ovarian Cancer|Stage IB Uterine Corpus Cancer|Stage IC Ovarian Cancer|Stage II Breast Cancer|Stage II Cervical Cancer|Stage II Ovarian Cancer|Stage II Uterine Corpus Cancer|Stage IIA Breast Cancer|Stage IIA Cervical Cancer|Stage IIA Ovarian Cancer|Stage IIB Breast Cancer|Stage IIB Cervical Cancer|Stage IIB Ovarian Cancer|Stage IIC Ovarian Cancer|Stage III Breast Cancer|Stage III Cervical Cancer|Stage III Ovarian Cancer|Stage III Uterine Corpus Cancer|Stage IIIA Breast Cancer|Stage IIIA Cervical Cancer|Stage IIIA Ovarian Cancer|Stage IIIA Uterine Corpus Cancer|Stage IIIB Breast Cancer|Stage IIIB Cervical Cancer|Stage IIIB Ovarian Cancer|Stage IIIB Uterine Corpus Cancer|Stage IIIC Breast Cancer|Stage IIIC Ovarian Cancer|Stage IIIC Uterine Corpus Cancer
Interventions: OTHER: Informational Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Promoting Intensive Transitions for Children and Youth With Medical Complexity From Pediatric to Adult Care
Status: RECRUITING
Conditions: Children and Youth With Medical Complexity
Interventions: OTHER: Intensive Transition Support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Reduction of the Metabolic Syndrome in Navarra-Spain
Status: COMPLETED
Conditions: Metabolic Syndrome|Obesity|Diabetes|Cardiovascular Disease
Interventions: BEHAVIORAL: Crononutrition|BEHAVIORAL: American Heart Association
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Nanocrystal Gels on the Management of Peri-implant Diseases
Status: NOT_YET_RECRUITING
Conditions: Dental Implant Failure Nos
Interventions: DEVICE: NeoPhylaxis|DEVICE: ImplanTreat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Consumption of Orange Juice on Vascular Protection and Immune Function: Clinical Study on the Specific Contribution of Citrus Flavanones
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Flavanones of orange juice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Dose Finding Study of Pegylated-P-Interferon-alpha-2b(P1101) in Treatment-Naive Subjects With Hepatitis C Virus Genotype 1 Infection
Status: COMPLETED
Conditions: Hepatitis C, Chronic
Interventions: BIOLOGICAL: PEGASYS 180 µg Q1W|BIOLOGICAL: P1101 180 µg Q1W, 48 doses|BIOLOGICAL: P1101 270µg Q1W, 48 doses|BIOLOGICAL: P1101 450µg Q2W, 24 doses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Intravenous Tranexamic Acid on Reduction of Blood Losses in Hip Fracture Patients
Status: COMPLETED
Conditions: Hip Fractures|Anemia
Interventions: DRUG: Tranexamic Acid|DRUG: Saline Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SAD of IVT PYC-001 in OPA1 Mutation-Associated Autosomal Dominant Optic Atrophy (Sundew)
Status: NOT_YET_RECRUITING
Conditions: OPA1 Gene Mutation|Autosomal Dominant Optic Atrophy|Hereditary Optic Atrophies|Kjer Optic Atrophy
Interventions: DRUG: PYC-001
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Relaxing Breathing With Biofeedback or Meditative Stimulation on Performances During OSCE of Medical Students
Status: COMPLETED
Conditions: Stress, Psychological|Stress, Physiological|Exam Stress|Performance Anxiety|Rumination
Interventions: OTHER: Biofeedback|OTHER: Meditation|OTHER: Control and biofeedback post OSCE|OTHER: Control and control post OSCE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Yttrium-90 Anti CD66 Monoclonal Antibody in Childhood Relapsed/Refractory Leukaemia
Status: COMPLETED
Conditions: Acute Myeloblastic Leukemia|Acute Lymphoblastic Leukemia|Juvenile Myelomonocytic Leukemia
Interventions: OTHER: Yttrium-90 labelled monoclonal antibody against CD66
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: First-line Treatment Of Subjects With Extensive Disease Small Cell Lung Cancer With Weekly Hycamtin And Paraplatin
Status: COMPLETED
Conditions: Lung Cancer, Small Cell
Interventions: DRUG: topotecan|DRUG: carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Smooth Extubation With Ketofol for Induction of General Anesthesia in Laparoscopic Drilling of Polycystic Ovary
Status: COMPLETED
Conditions: Smooth Extubation
Interventions: DRUG: Ketofol as induction agent|DRUG: Propofol as induction agent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Making SPARX Fly in Nunavut: Pilot Testing an E-intervention for Boosting Resilience Against Youth Depression
Status: COMPLETED
Conditions: Depressive Symptoms|Emotion Regulation
Interventions: OTHER: SPARX (Smart, Positive, Active, Realistic, X-Factor thoughts)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PMCF Study to Evaluate Performance and Safety of "Distilled Waters-based Eyedrops" Used to Relieve Dry Eye Symptoms
Status: COMPLETED
Conditions: Dry Eye|Dry Eye Disease|Kerato Conjunctivitis Sicca
Interventions: DEVICE: Distilled waters based eye drops
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Biofeedback Training's Impact on Cognitive and Motor Skills in Kids With Intellectual Disabilities
Status: RECRUITING
Conditions: Intellectual Disability, Mild
Interventions: OTHER: Biofeedback method|OTHER: Conventional therapy program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunological Effect of Pembrolizumab in Resectable or Borderline Resectable Pancreatic Cancer
Status: UNKNOWN
Conditions: Pancreatic Cancer
Interventions: DRUG: Pembrolizumab|RADIATION: Neoadjuvant Chemoradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I Protocol for the Evaluation of the Safety and Immunogenicity of Vaccination With Synthetic HIV Envelope Peptides in Patients With Early Human Immunodeficiency Virus Infection
Status: COMPLETED
Conditions: Acquired Immunodeficiency Syndrome|HIV Infection
Interventions: DRUG: PCLUS 3-18 MN|DRUG: PCLUS 6.1 MN
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: SAHARA-04 : Adaptive Radiotherapy in Hypersensitive Patients and High Locoregional Risk Breast Cancer With ETHOS Technology
Status: NOT_YET_RECRUITING
Conditions: Breast Cancer
Interventions: RADIATION: Treatment ETHOS radiotherapy|RADIATION: Conventional IMRT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Population Based Lighting Study on Older Adults
Status: RECRUITING
Conditions: Lightning Strategies on Health|Circadian Rhythms Photoentrainment|Photoentrainment and Sleep|DLMO
Interventions: BEHAVIORAL: indoor light intervention|BEHAVIORAL: no indoor light
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Cadonilimab Combined With Fruquintinib and SBRT as Athird-line and Posterior Line Treatment in Patients With MSS CRC
Status: RECRUITING
Conditions: Colorectal Cancer
Interventions: DRUG: Fruquintinib|DRUG: Cadonilimab|RADIATION: SBRT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Aprepitant/Dexamethasone Versus Mertazepine /Dexamethasone on Postoperative Nausea and Vomiting
Status: COMPLETED
Conditions: Nausea and Vomiting, Postoperative
Interventions: DRUG: Aprepitant and Dexamethasone|DRUG: Mirtazapine and Dexamethasone|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Reducing Skin Surface pH During Skin Occlusion: Changes to Skin Microbiome and Skin Parameters
Status: ACTIVE_NOT_RECRUITING
Conditions: Incontinence-associated Dermatitis
Interventions: OTHER: Test patches
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Secondary Interval Cytoreductive Surgery in Platinum-sensitive Recurrent Epithelial Ovarian Cancer
Status: RECRUITING
Conditions: Recurrent Ovarian Carcinoma
Interventions: PROCEDURE: Carboplatin or cisplatin|DRUG: Paclitaxel, gemcitabine or liposomal doxorubicin with or without bevacizumab or biosimilar|DRUG: Bevacizumab or biosimilar|PROCEDURE: Cytoreductive surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Validation Study of the Watch HWA09 and Its Softwares ECG-SW1 and PPG-SW1 for the Detection of Atrial Fibrillation
Status: COMPLETED
Conditions: Atrial Fibrillation|Arrythmia, Cardiac
Interventions: DEVICE: AF Detection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Growth Hormone and/or Rosiglitazone for HIV-Associated Increased Abdominal Fat and Insulin Resistance
Status: COMPLETED
Conditions: HIV-Associated Lipodystrophy Syndrome|Insulin Resistance|HIV Infections|Metabolic Syndrome X|Body Weight Changes
Interventions: DRUG: Rosiglitazone|DRUG: Recombinant human growth hormone + rosiglitazone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: XELOX in Advanced Biliary Tract Carcinoma After Failure of Gemcitabine-based Chemotherapy
Status: UNKNOWN
Conditions: Biliary Tract Cancer
Interventions: DRUG: capecitabine|DRUG: oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intraperitoneal Aerosolized Delivery of a Local Anesthetic for Post Operative Pain Management. A Double Blind, Randomised Controlled Clinical Trial.
Status: UNKNOWN
Conditions: Pain, Postoperative|Postoperative Pain|Abdominal Pain|Obesity|Pneumoperitoneum
Interventions: DEVICE: Intraperitoneal Aerosolization System, IntraMyst
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Study of TBX-3400 in Patients With Stage III and IV Melanoma Resistant or Refractory to Immune Checkpoint Inhibitors
Status: RECRUITING
Conditions: Stage III Melanoma|Stage IV Melanoma
Interventions: BIOLOGICAL: TBX-3400
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Repeated Doses of GnRH Agonist as Oocyte Triggering in Antagonist Protocol for Patients With Polycystic Ovary Syndrome
Status: COMPLETED
Conditions: Polycystic Ovary Syndrome
Interventions: OTHER: Repeated dose of GnRH agonist
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sipuleucel-T and Stereotactic Ablative Body Radiation (SABR) for Metastatic Castrate-resistant Prostate Cancer (mCRPC)
Status: COMPLETED
Conditions: Metastatic Castrate-resistant Prostate Cancer|mCRPC
Interventions: DRUG: Sipuleucel-T|RADIATION: Stereotactic Ablative Body Radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Peritoneal Cavity Conditioning Decreases Pain, Inflammation and Adhesions
Status: TERMINATED
Conditions: Endometriosis of the Cul-de-sac|Chocolate Cyst of Ovary|Fibroid/Myoma (Uterus/Cervix)
Interventions: PROCEDURE: full conditioning|PROCEDURE: standard pneumoperitoneum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Randomized Study of AZD2014 in Combination With Fulvestrant in Metastatic or Advanced Breast Cancer
Status: UNKNOWN
Conditions: Estrogen Receptor Positive Breast Cancer
Interventions: DRUG: AZD2014|DRUG: Everolimus|DRUG: Fulvestrant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Positron Emission Tomography Before Surgery in Evaluating Women With Primary or Recurrent Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: PROCEDURE: positron emission tomography|PROCEDURE: radionuclide imaging|RADIATION: fludeoxyglucose F 18
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy and Safety of Semaglutide Injection in Subjects With Type 2 Diabetes
Status: NOT_YET_RECRUITING
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Semaglutide Injection|DRUG: Semaglutide Injection(Ozempic®)|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Imatinib Discontinuation in Patients With Chronic Myeloid Leukemia Chronic Phase With Sustained MR4log
Status: UNKNOWN
Conditions: Leukemia, Myeloid, Chronic-Phase
Interventions: OTHER: imatinib discontinuation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dexamethasone (Sterodex) Versus Loteprendol (Lotemax) Eye Drops Following Strabismus Surgery
Status: UNKNOWN
Conditions: Ophthalmology
Interventions: DRUG: Loteprendol etabonate 0.5%|DRUG: Dexamethasone 0.1%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ketoprofen Topical Patch, 20% in the Treatment of Pain Associated With Osteoarthritis Flare of the Knee
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DRUG: Ketoprofen Topical Patch , 20%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Efficacy and Safety of Rituximab With Mycophenolate Mofetil in Patients With Interstitial Lung Diseases
Status: COMPLETED
Conditions: Lung Disease, Interstitial
Interventions: DRUG: Rituximab|DRUG: Placebo of Rituximab|DRUG: Mycophenolate Mofetil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial Comparing 3 Schedules of Hypofractionated Whole Breast Irradiation in Females With Early Stage Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer Female
Interventions: OTHER: Whole Breast Irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Postcoital Sponge on Self-Reported Vaginal Health Parameters
Status: NOT_YET_RECRUITING
Conditions: Vaginal Infection|Vaginal Discharge|Vaginosis|Sexual Dysfunction
Interventions: DEVICE: LiviWell Postcoital Vaginal Insert
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study to Compare the Pharmacokinetics, Safety, and Tolerability Following Administration of Palovarotene in Healthy Japanese and Non-Asian Subjects
Status: COMPLETED
Conditions: FOP
Interventions: DRUG: palovarotene low-dose|DRUG: palovarotene high-dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Chiropractic Spinal Manipulative Therapy for Acute Sciatica Secondary to Lumbar Disc Herniation
Status: UNKNOWN
Conditions: Acute Sciatica|Lumbar Disc Herniation
Interventions: OTHER: Chiropractic Spinal Manipulative Therapy|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Clinical Evaluation of Two Marketed Artificial Tears in Non-contact Lens Wearing Patients
Status: COMPLETED
Conditions: Visual Acuity
Interventions: DEVICE: Test Eye Drops|DEVICE: Control Eye Drops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Data Analysis for Drug Repurposing for Effective Alzheimer's Medicines (DREAM) - PDE5 Inhibitors vs Endothelin Receptor Antagonist
Status: COMPLETED
Conditions: Pulmonary Arterial Hypertension
Interventions: DRUG: PDE5 inhibitor|DRUG: Endothelin Receptor Antagonists
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Rapamycin for Immunosuppression and B Cell Modulation Post Stem Cell Transplant for Acute Lymphoblastic Leukemia (ALL)
Status: COMPLETED
Conditions: Acute Lymphoblastic Leukemia
Interventions: DRUG: RAPAMYCIN
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Forearm Tourniquet With Small Dose Intravenous Lidocaine
Status: UNKNOWN
Conditions: Local Anaesthesia
Interventions: PROCEDURE: intravenous regional anaesthesia|PROCEDURE: forearm IVRA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Immunogenicity Induced by the THV01 Treatment in Patients Infected With HIV-1 Clade B and Treated With Highly Active Antiretroviral Therapy (HAART).
Status: COMPLETED
Conditions: HIV Infection
Interventions: BIOLOGICAL: THV01-1|BIOLOGICAL: THV01-2|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Vitamin D Supplementation on Host Immunity to Mycobacterium Tuberculosis and Response to Treatment
Status: COMPLETED
Conditions: Tuberculosis
Interventions: DIETARY_SUPPLEMENT: Vitamin D pill|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Combining Interventions of Fertility Preservation to Mitigate Fertility Loss After Breast Cancer
Status: RECRUITING
Conditions: Breast Cancer Female
Interventions: PROCEDURE: Ovarian biopsy via laparoscopy|PROCEDURE: Transvaginal oocyte retrieval
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Clinical Outcomes and Costs Analyses in Use of Goal Directed Therapy
Status: COMPLETED
Conditions: Postoperative Complications
Interventions: DEVICE: Goal Directed Fluid Therapy FloTrac/Vigileo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Spine Pain INtervention to Enhance Care Quality And Reduce Expenditure
Status: COMPLETED
Conditions: Back Pain|Neck Pain
Interventions: OTHER: Identify, Coordinated, Enhanced (ICE) Decision Making + PCP led care|OTHER: Individualized Postural Therapy (IPT) + PCP led care|OTHER: Usual PCP led care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of the Whisperflow CPAP System Versus Nasal High Flow in Patients at High Risk for Postextubation Failure
Status: UNKNOWN
Conditions: Respiratory Failure
Interventions: DEVICE: Nasal high-flow|DEVICE: CPAP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Vitamin C to Reduce Vasopressor Dose in Septic Shock
Status: WITHDRAWN
Conditions: Septic Shock|Sepsis
Interventions: DRUG: Vitamin C|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Integrated Patient Care Intradialysis Programme in Hemodialysis Through a Virtual Health Platform
Status: RECRUITING
Conditions: End Stage Renal Disease|Hemodialysis-Induced Symptom|Chronic Kidney Diseases
Interventions: OTHER: Virtual reality health platform during hemodialysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of FP-025, on Allergen-induced Airway Responses in Mild Eosinophilic House Dust Mite (HDM)-Allergic Asthma.
Status: COMPLETED
Conditions: Asthma, COPD
Interventions: DRUG: FP-025 capsules|DRUG: Placebo FP-025 capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Dose-response Trial Using rFSH FE 999049 in Women Undergoing IVF/ICSI Treatment
Status: COMPLETED
Conditions: Infertility
Interventions: DRUG: FE 999049|DRUG: Gonal - F
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Trial Of Platelet Transfusion Policies After Blood Stem Cells Transplantation In Young Children: Reduction Of Number Of Single Platelet Concentrate Donors Per Child
Status: UNKNOWN
Conditions: Children Treated With High-Dose Chemotherapy (HDC) Followed by Haematopoietic Stem Cell Transplantation (HSCT)
Interventions: PROCEDURE: Platelet concentrates
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Human Amniotic Membrane and Mesenchymal Stem Cells Composite
Status: UNKNOWN
Conditions: Brachial Plexus Neuropathies
Interventions: PROCEDURE: Nerve transfer procedure|PROCEDURE: Nerve transfer with HAM-AdMSC composite wrapping
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Growth and Tolerance of Young Infants Fed Infant Formulas
Status: COMPLETED
Conditions: Infant Newborn
Interventions: OTHER: experimental infant formula with alternate protein source|OTHER: Infant formula powder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Combination of Vemurafenib, Cytarabine and 2-chlorodeoxyadenosine in Children With LCH and BRAF V600E Mutation
Status: RECRUITING
Conditions: Langerhans Cell Histiocytosis
Interventions: DRUG: Vemurafenib|DRUG: Cytarabine|DRUG: 2-chlorodeoxyadenosine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cetuximab-IRDye 800CW in Detecting Tumors in Patients With Malignant Glioma Undergoing Surgery
Status: TERMINATED
Conditions: Brain Neoplasm|Malignant Glioma
Interventions: BIOLOGICAL: Cetuximab|DRUG: Cetuximab-IRDye 800CW|PROCEDURE: Tumor resection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect on Allogenic Mesenchymal Stem Cells on Osseointegration of Dental Implants
Status: UNKNOWN
Conditions: Edentulous Alveolar Ridge
Interventions: DRUG: Allogenic Mesenchymal stem cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: mil60 Versus Bevacizumab in Patients With Treatment-naïve Non-squamous Non-small Cell Lung Cancer
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: mil60|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: HALT Progression of Polycystic Kidney Disease Study A
Status: COMPLETED
Conditions: Kidney, Polycystic
Interventions: DRUG: Lisinopril|DRUG: Telmisartan|DRUG: Placebo|OTHER: Standard Blood Pressure Control|OTHER: Low Blood Pressure Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pudendal Block Using Liposomal Bupivacaine vs. Standard Treatment During Sacrospinous Ligament Fixation
Status: UNKNOWN
Conditions: Vaginal Prolapse
Interventions: DRUG: Liposomal Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Safety, Tolerability, PK and PD of DCR-PHXC in PH Type 3 Patients
Status: COMPLETED
Conditions: Primary Hyperoxaluria Type 3
Interventions: DRUG: DCR-PHXC|DRUG: Sterile Normal Saline (0.9% NaCl)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Echocardiography Examination Of The Cardiac Effects Of Different Regional Anesthesia Methods
Status: UNKNOWN
Conditions: Femur Fracture|Spinal Anesthesia|Lumbar Plexus Block
Interventions: DEVICE: Transthoracic echocardiogram
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Fresh Frozen Plasma and Plasmalyte ® for Priming Cardiopulmonary Bypass in Infants and Children
Status: COMPLETED
Conditions: Congenital Heart Disease
Interventions: PROCEDURE: Surgery with CPB|OTHER: Fresh Frozen Plasma|OTHER: Plasmalyte
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: New Cross-linked Hyaluronan Gel to Prevent Adhesion After USG-MVA: RCT
Status: RECRUITING
Conditions: First Trimester Abortion|Surgical Abortion|Miscarriage With Afibrinogenemia
Interventions: DEVICE: MateRegen® gel (BioRegen)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Phase 1/2 Study to Determine Optimal Dose for Treating Bone Metastases Using Novel STAT-RT Workflow
Status: UNKNOWN
Conditions: Metastatic Bone Lesion
Interventions: RADIATION: Stereotactic Body Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lucky Iron Fish Home Fortification of Iron
Status: COMPLETED
Conditions: Anemia|Anemia, Iron-Deficiency|Hemoglobinopathies
Interventions: OTHER: Lucky Iron Fish - home fortification system|DIETARY_SUPPLEMENT: 18 mg elemental iron|OTHER: Nutrition Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Acarbose, Postprandial Hypotension and Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes|Postprandial Hypotension
Interventions: DRUG: Acarbose|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ultra Low-Dose Radiation Therapy in Treating Patients With Stage I-IV Stomach MALT Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Gastric Mucosa-Associated Lymphoid Tissue Lymphoma
Interventions: DRUG: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Behavioural Activation on Emotional Cognition and Mood
Status: COMPLETED
Conditions: Depression|Depressive Disorder|Mood Disorders|Cognition
Interventions: BEHAVIORAL: Behavioural activation|BEHAVIORAL: Activity monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Tracleer (Bosentan) on Pulmonary Arterial Hypertension Related to Eisenmenger Physiology
Status: COMPLETED
Conditions: Pulmonary Arterial Hypertension Related to Eisenmenger Physiology
Interventions: DRUG: bosentan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence and Wear Study of Mylan Fentanyl Transdermal System 25 µg/h and Mylan Fentanyl Transdermal System With Askina Derm Overlay
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Fentanyl Transdermal System 25 mcg/h + Askina Derm Overlay|DRUG: Fentanyl Transdermal System 25 mcg/h
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Efficacy of Metacognitive Training Single Modules: Jumping to Conclusions and To Empathize...
Status: COMPLETED
Conditions: Schizophrenia|Psychotic Disorders
Interventions: BEHAVIORAL: Metacognitive Training Jumping to Conclusion|BEHAVIORAL: Group discussion|BEHAVIORAL: Metacognitive Training To Empathize
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, Pharmacodynamic Effects and Preliminary Evidence for Efficacy of the Anti-Hypertension Vaccine CYT006-AngQb
Status: COMPLETED
Conditions: Essential Hypertension
Interventions: BIOLOGICAL: CYT006-AngQb
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Chronic Lymphocytic B-Leukemia With IL-2 and CD-40 Autologous Tumor Cells
Status: COMPLETED
Conditions: Chronic Lymphocytic B-Leukemia
Interventions: BIOLOGICAL: Injection of IL-2-secreting CD40L-expressing autologous B-CLL cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Durvalumab in Patients With HER-2 Positive Metastatic Breast Cancer Receiving Trastuzumab
Status: COMPLETED
Conditions: Metastatic Breast Cancer
Interventions: DRUG: Durvalumab|DRUG: Trastuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study to Assess the Safety, Tolerability, and Pharmacokinetics of PUR3100 in Health Adults
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: PUR3100|DRUG: Dihydroergotamine (D.H.E 45)|OTHER: Matching Placebo for PUR3100|OTHER: Matching Placebo for D.H.E 45
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Primary Cyto-reductive Surgery Vs Neo-adjuvant Chemotherapy (NAC) in Epithelial Ovarian Cancer
Status: UNKNOWN
Conditions: Advanced Cancer
Interventions: PROCEDURE: 1ry cyto-reductive surgery|COMBINATION_PRODUCT: Neoadjuvant chemotherapy followed by surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess ACH-0145228 When Administered as Immediate Release Tablet Versus Powder-In-Capsule in Healthy Adult Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: ACH-0145228: Immediate Release|DRUG: ACH-0145228: Powder-in-capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE