pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Effects of Omega-3 Fatty Acids on Bone and Frailty
Status: UNKNOWN
Conditions: Osteoporosis|Frailty
Interventions: DIETARY_SUPPLEMENT: DHA/EPA|DIETARY_SUPPLEMENT: Placebo capsule|DIETARY_SUPPLEMENT: Calcium with vitamin D
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PH Weighted Chemical Exchange Saturation Transfer MRI-Based Surgical Resection to Improve Survival in Patients With Glioblastoma
Status: NOT_YET_RECRUITING
Conditions: Glioblastoma
Interventions: PROCEDURE: Chemical Exchange Saturation Transfer Magnetic Resonance Imaging|PROCEDURE: Contrast-enhanced Magnetic Resonance Imaging|PROCEDURE: Magnetic Resonance Imaging|RADIATION: Radiation Therapy|PROCEDURE: Surgical Procedure|DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Enhancing SKIN Health and Safety in Aged CARE
Status: COMPLETED
Conditions: Xerosis Cutis|Dry Skin|Pruritus|Pressure Ulcer|Intertrigo|Incontinence-associated Dermatitis|Skin Tear|Skin Care
Interventions: OTHER: Implementation of skin care algorithm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: DUPIlumab Dose REDUCtion in Patients With Controlled Atopic Eczema
Status: RECRUITING
Conditions: Atopic Dermatitis|Atopic Dermatitis Eczema
Interventions: DRUG: Dupilumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Anamnestic Immune Response in Healthy 4 to 7 Year-old Children After a Primary Vaccination Series With Either HEXAVAC® or INFANRIX®-HEXA
Status: COMPLETED
Conditions: Hepatitis B
Interventions: BIOLOGICAL: HBVaxPRO® 5 µg / 0.5 mL|BIOLOGICAL: Engerix B® 10 µg / 0.5 mL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Magnetic Resonance Imaging and Thermal Imaging of Adiposity in Neonates of Women With Metabolic Diseases
Status: UNKNOWN
Conditions: Diabetes Mellitus|Intrahepatic Cholestasis of Pregnancy|Metabolic Disease
Interventions: DIAGNOSTIC_TEST: Thermal imaging|DIAGNOSTIC_TEST: Echocardiogram|DIAGNOSTIC_TEST: ECG|DIAGNOSTIC_TEST: MRI scan|DIAGNOSTIC_TEST: Serum blood markers
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Capecitabine + Irinotecan Followed by Combined Modality Capecitabine and Radiation in Locally Advanced Rectal Cancer
Status: TERMINATED
Conditions: Rectal Cancer
Interventions: DRUG: Capecitabine|DRUG: Irinotecan|PROCEDURE: EUS|DRUG: Neoadjuvant Chemotherapy|PROCEDURE: Preoperative Radiation|PROCEDURE: Surgery|PROCEDURE: Adjuvant Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Metacognitive Training for Schizophrenia - a Study Protocol
Status: COMPLETED
Conditions: Schizophrenia
Interventions: BEHAVIORAL: Metacognitive Training in Schizophrenia (MCT)|OTHER: Treatment As Usual (TAU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of Microwave Ablation With Breast Conserving Surgery for Breast Tumor
Status: UNKNOWN
Conditions: Breast Tumor|Microwave Ablation|Breast Conserving Surgery
Interventions: PROCEDURE: microwave ablation|PROCEDURE: breast conserving surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Homeopathic Treatment of Chronic Pelvic Pain in Women With Endometriosis
Status: COMPLETED
Conditions: Endometriosis|Pelvic Pain
Interventions: DRUG: dynamized estrogen|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Locally Delivered Doxycycline Adjunct to Nonsurgical Periodontal Therapy.
Status: COMPLETED
Conditions: Periodontal Disease
Interventions: DRUG: Doxicicline|PROCEDURE: Full-mouth debridment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: MENJAGA: Continuous Quality Improvement for Antenatal HIV, Syphilis and Hepatitis B Testing in Indonesia
Status: NOT_YET_RECRUITING
Conditions: Hiv|Syphilis|Hepatitis B
Interventions: OTHER: Continuous quality improvement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: TSA Techniques in Glenohumeral OA
Status: RECRUITING
Conditions: Osteoarthritis, Shoulder
Interventions: PROCEDURE: Eccentric Reaming|PROCEDURE: Augmented Glenoid Component Implantation|PROCEDURE: Posterior Glenoid Bone Grafting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mesenchymal Stem Cells for Treatment of Poor Graft Function After Allogeneic Hematopoietic Stem Cell Transplant
Status: UNKNOWN
Conditions: Stem Cell Transplantation, Hematopoietic|Mesenchymal Stem Cells|Poor Graft Function|Hematological Diseases
Interventions: BIOLOGICAL: Mesenchymal stem cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Telephone-delivered Mindfulness Intervention for African American Dementia Caregivers
Status: COMPLETED
Conditions: Alzheimer Dementia|Caregiver|Dementia Alzheimers
Interventions: BEHAVIORAL: Telephone-delivered Mindfulness
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Gefitinib Combined With Thalidomide to Treat NSCLC
Status: UNKNOWN
Conditions: NSCLC
Interventions: DRUG: Thalidomide|DRUG: placebo|DRUG: Gefitinib|DRUG: Aspirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Chidamide Plus Etoposide and Cisplatin/Carboplatin as First-line Treatment for Extrapulmonary Neuroendocrine Carcinoma
Status: RECRUITING
Conditions: Neuroendocrine Tumors|Neuroendocrine Carcinoma
Interventions: DRUG: Chidamide|DRUG: Etoposide + Cisplatin/Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vestibular Rehabilitation for Persons With Multiple Sclerosis: Who Benefits the Most? (MSVR3trial)
Status: COMPLETED
Conditions: Multiple Sclerosis|Balance|Fatigue|Eye Movement
Interventions: OTHER: Vestibular rehabilitation: balance and eye movement exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: 8 Week Multi-site Study of MYDAYIS® for Bipolar Depression
Status: RECRUITING
Conditions: Bipolar Depression
Interventions: DRUG: Mydayis Extended-Release Capsule|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Explore the the Amyloid Beta Draining Effect of Thiethylperazine (TEP) in Subjects With Newly Diagnosed Early-to-mild Dementia Due to Alzheimer's Disease (AD) in Comparison to Healthy Volunteers
Status: COMPLETED
Conditions: Alzheimer Disease
Interventions: DRUG: TEP
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transcranial Magnetic Stimulation and Mental Representation Techniques for the Treatment of Stroke Patients
Status: COMPLETED
Conditions: Stroke
Interventions: DEVICE: Repetitive Transcranial Magnetic Stimulation (rTMS)|DEVICE: Motor Imagery (MI) through a Brain-Computer Interface (BCI) training platform in Virtual Reality (VR) with NeuRow
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Palonosetron in Preventing Chemotherapy-induced Nausea and Vomiting
Status: COMPLETED
Conditions: Nausea|Vomiting|Chemotherapy
Interventions: DRUG: Palonosetron|DRUG: Granisetron
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phase II Study to Evaluate the Efficacy and Safety of 177Lu-Dotatate in the First-line Treatment of Patients With Locally Advanced or Metastatic, Somatostatin Receptor-positive G2 or G3 Gastroenteropancreatic Neuroendocrine Tumors
Status: NOT_YET_RECRUITING
Conditions: Neuroendocrine Tumors
Interventions: DRUG: Lutetium[177Lu] Oxodotreotide Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non-dependent HFPPV Versus CPAP for Video-assisted Thoracoscopy
Status: COMPLETED
Conditions: Elective Video-assisted Thoracoscopic Surgery|One-lung Ventilation Lasts at Least One Hour
Interventions: PROCEDURE: Non-dependent lung ventilation|PROCEDURE: Non-dependent lung ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dual Tasking and Upper Extremity Disability in Adolescent Idiopathic Scoliosis
Status: RECRUITING
Conditions: Scoliosis Idiopathic
Interventions: OTHER: Single and Dual-Task Timed Up and Go Test|OTHER: Single and Dual-Task Tandem Walking Test|OTHER: Simple Shoulder Test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study Evaluating Nelotanserin for Treatment of REM Sleep Behavior Disorder in Subjects With Dementia (DLB or PDD)
Status: COMPLETED
Conditions: Dementia With Lewy Bodies|REM Sleep Behavior Disorder|Parkinson's Disease Dementia
Interventions: DRUG: Nelotanserin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fibromyalgia Sleep A to ZZZ Study
Status: NOT_YET_RECRUITING
Conditions: Fibromyalgia
Interventions: DEVICE: Light Therapy|BEHAVIORAL: Sleep Stabilization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of Two Different Pelvic Floor Muscle Training Programs in Stress Urinary Incontinence
Status: COMPLETED
Conditions: Stress Urinary Incontinence
Interventions: OTHER: Classical Pelvic Floor Muscle Training|OTHER: Functional Pelvic Floor Muscle Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Plasmodium Falciparum Exposure and Sickle Cell Trait on Infection Rates and Kinetics After IV Administration of PfSPZ Challenge
Status: COMPLETED
Conditions: Plasmodium Falciparum Malaria|Malaria
Interventions: BIOLOGICAL: PfSPZ Challenge
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: engAGE: Managing cognitivE decliNe throuGh Theatre Therapy, Artificial Intelligence and Social Robots drivEn Interventions
Status: RECRUITING
Conditions: Mild Cognitive Impairment|Older Adults
Interventions: DEVICE: engAGE system|OTHER: Group practicing with only the support of a booklet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Impact Of Different Ablation Approaches on Outcome In Coexistent Atrial Fibrillation and Flutter
Status: COMPLETED
Conditions: Atrial Arrhythmia|Quality of Life
Interventions: PROCEDURE: Catheter ablation|PROCEDURE: Catheter ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Low-Dose Intravenous Ketamine Bolus Versus Conventional Technique
Status: UNKNOWN
Conditions: Procedural Sedation
Interventions: DRUG: Ketamine Hydrochloride 50Mg/1mL Solution for Injection|DRUG: Ketamine Hcl 50Mg/Ml Inj
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: First-in-Human Positron Emission Tomography Study Using the 18F-αvβ6-Binding-Peptide
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Carcinoma|Colorectal Carcinoma|Lung Carcinoma|Metastatic Malignant Neoplasm in the Breast|Metastatic Malignant Neoplasm in the Colon|Metastatic Malignant Neoplasm in the Lung|Metastatic Malignant Neoplasm in the Rectum|Pancreatic Carcinoma
Interventions: DRUG: 18F-αvβ6-BP
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ventricular Arrhythmias Incidence According to Sleep Apnea Syndrome in Implantable Cardioverter-Defibrillator (ICD) Patients
Status: COMPLETED
Conditions: Sleep Apnoea
Interventions: DEVICE: ICD|DEVICE: CRT-D
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Epcoritamab and Tazemetostat for the Treatment of Relapsed or Refractory Grade I-IIIa Follicular Lymphoma
Status: NOT_YET_RECRUITING
Conditions: Recurrent Grade 1 Follicular Lymphoma|Recurrent Grade 2 Follicular Lymphoma|Recurrent Grade 3a Follicular Lymphoma|Refractory Grade 1 Follicular Lymphoma|Refractory Grade 2 Follicular Lymphoma|Refractory Grade 3a Follicular Lymphoma
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Bone Marrow Biopsy|PROCEDURE: Computed Tomography|BIOLOGICAL: Epcoritamab|PROCEDURE: Positron Emission Tomography|DRUG: Tazemetostat
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing the Effect of Chiropractic Manipulation and Spinal Decompression Device Treatment
Status: COMPLETED
Conditions: Chronic Low-back Pain
Interventions: OTHER: Chiropractic Manipulation|OTHER: Spinal Decompression Device Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study in Severe Patients With Takayasu Arteritis.
Status: RECRUITING
Conditions: Takayasu Arteritis|Tocilizumab|Adalimumab|Treatment
Interventions: BIOLOGICAL: Tocilizumab|BIOLOGICAL: Adalimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anti-adhesive Effect and Safety of "Thermo-sensitive Adhesion Barrier (MEDICLORE)"
Status: COMPLETED
Conditions: Adhesion|Thyroidectomy
Interventions: COMBINATION_PRODUCT: MEDICLORE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Lenalidomide, Cytarabine, and Idarubicin in Treating Patients With Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome|Adult Acute Myeloid Leukemia With Inv(16)(p13.1q22); CBFB-MYH11|Adult Acute Myeloid Leukemia With t(16;16)(p13.1;q22); CBFB-MYH11|Adult Acute Myeloid Leukemia With t(8;21)(q22;q22); RUNX1-RUNX1T1|Adult Acute Myeloid Leukemia With t(9;11)(p22;q23); MLLT3-MLL|Adult Acute Promyelocytic Leukemia With t(15;17)(q22;q12); PML-RARA|Alkylating Agent-Related Acute Myeloid Leukemia|de Novo Myelodysplastic Syndrome|Previously Treated Myelodysplastic Syndrome|Recurrent Adult Acute Myeloid Leukemia|Secondary Acute Myeloid Leukemia|Secondary Myelodysplastic Syndrome|Untreated Adult Acute Myeloid Leukemia
Interventions: DRUG: Lenalidomide|DRUG: Cytarabine|DRUG: Idarubicin|OTHER: Pharmacological Study|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Histamine H3 Receptor Radioligand [11C]AZ12807110 and Histamine H3 Receptor Occupancy of AZD5213 After Oral Administration
Status: COMPLETED
Conditions: Brain Distribution of [11C]AZ12807110 and AZD5213
Interventions: OTHER: [11C]AZ12807110|DRUG: AZD5213
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study to Compare the Addition of Umeclidinium Bromide (UMEC) to Fluticasone Furoate (FF)/Vilanterol (VI), With Placebo Plus FF/VI in Subjects With Chronic Obstructive Pulmonary Disease (COPD) -Study 2
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: FF|DRUG: VI|DRUG: UMEC|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prophylactic Entecavir for HBV Reactivation in Past HBV Infected Patients With Hematopoietic Stem Cell Transplantation
Status: ENROLLING_BY_INVITATION
Conditions: Hepatitis B Reactivation|Hematopoietic Stem Cell Transplantation|Antiviral Drug|HBV
Interventions: DRUG: Entecavir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TAmoxifen Versus LIdocaine Cream. A Randomized Clinical Trial for Reducing Pain and Discomfort During Mammography
Status: UNKNOWN
Conditions: Pain|Discomfort
Interventions: DRUG: Placebo|DRUG: Lidocaine|DRUG: Tamoxifen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Restoring Vision With the Intelligent Retinal Implant System (IRIS V1)in Patients With Retinal Dystrophy
Status: COMPLETED
Conditions: Retinitis Pigmentosa|Cone Rod Dystrophy|Choroideremia
Interventions: DEVICE: Intelligent Retinal Implant System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect Low Pressure Pneumoperitoneum and Pulmonary Recruitment on Postoperative Pain
Status: UNKNOWN
Conditions: Pneumoperitoneum|Recruitment|Postoperative Pain
Interventions: PROCEDURE: Pulmonary recruitment|PROCEDURE: No pulmonary recruitment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Multifamily Psychoeducation and Cognitive Remediation for Recent-Onset Psychosis
Status: COMPLETED
Conditions: Recent-Onset Psychosis|Schizophrenia|Schizoaffective Disorder|Bipolar Disorder With Psychotic Features|Major Depression With Psychotic Features|Psychotic Disorder Not Otherwise Specified (NOS)
Interventions: BEHAVIORAL: Multifamily Group Psychoeducation (MFG)|BEHAVIORAL: Cognitive Remediation (CR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Aspirin on Gut Microbiome
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Aspirin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Echocardiography Versus no Echocardiography in S. Aureus Bacteraemia and VIRSTA Score < 3
Status: NOT_YET_RECRUITING
Conditions: Staphylococcus Aureus|Bacteremia|Infective Endocarditis
Interventions: PROCEDURE: systematic echocardiography|PROCEDURE: no echocardiography arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Karydakis Procedure Vs Limberg Flap in Treatment of Sacrococcygeal Pilonidal Sinus
Status: COMPLETED
Conditions: Pilonidal Sinus
Interventions: PROCEDURE: Karydakis procedure|PROCEDURE: Limberg Flap
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Colchicine Resistance in Familial Mediterranean Fever
Status: COMPLETED
Conditions: Mediterranean Fever|Colchicine Resistance
Interventions: BIOLOGICAL: Capillary colchicine dosage in colchicine-resistant Familial Mediterranean Fever patients.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Evaluate the Safety and Efficacy of Max-40279 and Toripalimab in Patients With Advanced Solid Tumors
Status: UNKNOWN
Conditions: Solid Tumor
Interventions: DRUG: "MAX-40279-01" and "Toripalimab"
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Time Spent on Floor After Falls of Frailty People Overnight
Status: WITHDRAWN
Conditions: Dependence|Fall From Bed|Fall Injury|Fall in Nursing Home|Cognition Disorders
Interventions: OTHER: run-in period|DEVICE: Control period|DEVICE: Etolya-F ® devices
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: A Clinical Study to Evaluate the Safety and Tolerability of JS001sc in Advanced Nasopharyngeal Carcinoma
Status: RECRUITING
Conditions: Advanced Nasopharyngeal Carcinoma
Interventions: BIOLOGICAL: Toripalimab injection(subcutaneous)/JS001sc|BIOLOGICAL: Toripalimab injection(subcutaneous)/JS001sc|BIOLOGICAL: Toripalimab /JS001|BIOLOGICAL: Toripalimab injection(subcutaneous)/JS001sc
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Healthy Diet and Lifestyle Study II
Status: RECRUITING
Conditions: Intra-Abdominal Fat
Interventions: BEHAVIORAL: IER+MED|BEHAVIORAL: MED/DER
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Sarpogrelate and High Dose Statin on the Reduction of Coronary Spasm
Status: UNKNOWN
Conditions: Variant Angina
Interventions: DRUG: Sarpogrelate|DRUG: Atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Nitric Oxide-Releasing Acetylsalicyclic Acid in Preventing Colorectal Cancer in Patients at High Risk of Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: nitric oxide-releasing acetylsalicylic acid derivative|OTHER: laboratory biomarker analysis|PROCEDURE: biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Early Intervention Based on Neonatal Crawling in Very Premature Infants Without Major Brain Damage
Status: ACTIVE_NOT_RECRUITING
Conditions: Prematurity
Interventions: BEHAVIORAL: Crawling stimulation with the crawliskate|BEHAVIORAL: Tummy time without the crawliskate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evolocumab Added to Statin Therapy in Symptomatic Intracranial Atherosclerotic Stenosis (EAST-ICAS)
Status: RECRUITING
Conditions: Stroke Patients With Symptomatic Intracranial Atherosclerotic Stenosis
Interventions: DRUG: Evolocumab|DRUG: Atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Quality Improvement to Reduce Mortality or Severe Intracranial Hemorrhage in Neonatal Extracorporeal Life Support
Status: WITHDRAWN
Conditions: Extracorporeal Life Support|Extracorporeal Membrane Oxygenation|Quality Improvement|Intracranial Hemorrhage|Mortality|Neonate
Interventions: BEHAVIORAL: Collaborative quality improvement
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nationwide Utilization of Danish Government Electronic Letter System for Increasing Guideline-directed Medical Therapy in Chronic Kidney Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Kidney Diseases|Behavior and Behavior Mechanisms
Interventions: BEHAVIORAL: Electronically delivered nudging letters to patients with CKD|BEHAVIORAL: Electronically delivered nudging letter to associated GPs of patients with CKD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study of the Safety and Efficacy of UHE-105 Shampoo in Subjects With Scalp Psoriasis
Status: COMPLETED
Conditions: Scalp Psoriasis
Interventions: DRUG: UHE-105|DRUG: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Investigational Scan (64Cu-Labeled M5A Antibody) in Combination With SOC Chemotherapy and Radiotherapy in Locally Advanced Rectal Cancer
Status: RECRUITING
Conditions: Locally Advanced Rectal Carcinoma|Stage III Rectal Cancer AJCC v8|Stage IIIA Rectal Cancer AJCC v8|Stage IIIB Rectal Cancer AJCC v8|Stage IIIC Rectal Cancer AJCC v8
Interventions: BIOLOGICAL: Copper Cu 64 Anti-CEA Monoclonal Antibody M5A|PROCEDURE: Imaging Technique
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intraoperative Diagnosis of Neurocognitive Complications Via Electroencephalographic Analysis
Status: NOT_YET_RECRUITING
Conditions: Surgery|Postoperative Delirium|Anesthesia|Silent Stroke|Emergence Delirium
Interventions: DEVICE: Intraoperative electroencephalography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Spartan Cube CYP2C19 Method Comparison Study
Status: COMPLETED
Conditions: Genotyping Techniques
Interventions: DEVICE: Spartan Cube CYP2C19 System
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SCREENING
Clinical trial: A Study of Olumacostat Glasaretil Gel in Subjects With Acne Vulgaris
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: Olumacostat Glasaretil Gel, 5.0%|OTHER: Olumacostat Glasaretil Gel, Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Structured Shared Decision Making for Patients Undergoing SAVR or TAVR
Status: RECRUITING
Conditions: Aortic Valve Stenosis|Symptomatic Aortic Stenosis
Interventions: OTHER: Structured SDM|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison Between Different Filling Pressures in Diagnostic Outpatient Hysteroscopy
Status: COMPLETED
Conditions: Hysteroscopy
Interventions: DEVICE: Filling pressure 80|DEVICE: Filling pressure 50|DEVICE: Filling pressure 30
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Ergonomic Classroom Furniture on the Printing Legibility of Elementary Students With Cerebral Palsy
Status: COMPLETED
Conditions: Cerebral Palsy
Interventions: DEVICE: ergonomic chair and desk (Q-Learn Classic Chair and Q-Learn Desk)|DEVICE: ergonomic desk and chair (Q-Learn Desk)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Stem Cell Therapy to Improve the Muscle Function of Patients With Partly Denervated Muscles of the Arm
Status: UNKNOWN
Conditions: Brachial Plexus Injury
Interventions: PROCEDURE: Mononuclear cell injection: 4 * 10e8 cells|PROCEDURE: Mononuclear cell injection: 8 * 10e8 cells|PROCEDURE: No mononuclear cell injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Histological Outcome of the Use of Different Biomaterials for Fresh Socket Regeneration. A Split-mouth Design
Status: COMPLETED
Conditions: Alveolar Bone Loss
Interventions: PROCEDURE: dental socket regeneration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating Three Methods for Helping Syringe Exchangers Begin Methadone Maintenance
Status: COMPLETED
Conditions: Substance Abuse Disorder
Interventions: BEHAVIORAL: Low intensity care|BEHAVIORAL: Voucher reinforcement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A RCT of the Efficacy of Vonoprazan 20mg QD in the Treatment of Helicobacter Pylori Infection
Status: RECRUITING
Conditions: Vonoprazan|Helicobacter Pylori Infection|Proton Pump Inhibitor
Interventions: DRUG: Vonoprazan Tablets|DRUG: Amoxicillin Capsules|DRUG: Esomeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Therapeutic Zinc in Infant Bacterial Illness
Status: COMPLETED
Conditions: Sepsis|Bacterial Infections|Pneumonia
Interventions: DRUG: Drug: Zinc (zinc sulphate)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Proposal to Test the Efficacy and Tolerability of Bortezomib in Pulmonary Chronic GVHD
Status: TERMINATED
Conditions: Bronchiolitis Obliterans
Interventions: DRUG: Bortezomib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Study for Solid Metastatic Tumors
Status: COMPLETED
Conditions: Breast Cancer|Metastatic Breast Cancer|Solid Tumor
Interventions: RADIATION: Radiation therapy|DRUG: Xeloda|DRUG: paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Palbociclib in Combination With Bicalutamide for the Treatment of AR(+) Metastatic Breast Cancer (MBC)
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Breast Cancer (MBC)
Interventions: DRUG: Palbociclib|DRUG: Bicalutamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Environment's Impact on Thinking When Added to Leg Cycling in People With TBI: VITAL
Status: COMPLETED
Conditions: Traumatic Brain Injury
Interventions: BEHAVIORAL: Exercise Only|BEHAVIORAL: Exercise + Non-Immersive Virtual Reality|BEHAVIORAL: Exercise + Immersive Virtual Reality
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Safety, Tolerability and Pharmacokinetics of Nivolumab in Chinese Subjects With Previously Treated Advanced or Recurrent Solid Tumors
Status: COMPLETED
Conditions: Solid Tumors
Interventions: DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Accurately Assess Lymph Node Response to NACT by Wire Localization of Clip-marked Lymph Nodes
Status: UNKNOWN
Conditions: Neoplasm, Breast|Neoadjuvant Chemotherapy|Lymph Node Metastases|Response
Interventions: PROCEDURE: wire localization
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Implantable Microdevice for TNBC - Pilot Study
Status: WITHDRAWN
Conditions: Triple Negative Breast Cancer|Breast Cancer Stage II|Breast Cancer Stage III|Breast Cancer|Early Stage Triple-Negative Breast Carcinoma|Breast Neoplasms|Breast Carcinoma
Interventions: COMBINATION_PRODUCT: Implantable Microdevice (IMD)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Substance P Antagonist in the Treatment of Posttraumatic Stress Disorder
Status: COMPLETED
Conditions: PTSD
Interventions: DRUG: NK1 Antagoist (GR205171)|PROCEDURE: Psychophysiology (Trauma Script)|PROCEDURE: Psychophysiology (Verbal Threat)|PROCEDURE: Psychophysiology (Fear Conditioning)|PROCEDURE: Psychophysiology (Affective Modulation)|PROCEDURE: Psychophysiology (Heart rate variability)|PROCEDURE: Lumbar Puncture|PROCEDURE: 24-hour plasma sampling|PROCEDURE: MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Long-term Treatment Study of MRA for Rheumatoid Arthritis (RA) From Study MRA220JP or MRA221JP
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: MRA(Tocilizumab)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety Study of FSME-IMMUN 0.5 mL in Adult Subjects Previously Vaccinated According to a Rapid Immunization Schedule
Status: COMPLETED
Conditions: Encephalitis, Tick-Borne
Interventions: BIOLOGICAL: Formaldehyde inactivated, sucrose gradient purified TBE virus antigen, strain Neudörfl
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Activity-Based Therapy and Transcutaneous Spinal Cord Stimulation After Spinal Cord Injury (ABT-TCSCS)
Status: RECRUITING
Conditions: Spinal Cord Injuries|Spinal Cord Injury Cervical
Interventions: OTHER: Activity-based therapy and transcutaneous spinal cord stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MPH966 for Prevention of Graft-versus-host Disease After Allogeneic Hematopoietic Stem Cell Transplantation
Status: WITHDRAWN
Conditions: Hematologic Malignancy
Interventions: DRUG: MPH966|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Additional Effect of Pain Neuroscience Education to Spinal Manipulative Therapy in Chronic Low Back Pain
Status: COMPLETED
Conditions: Low Back Pain
Interventions: PROCEDURE: Spinal Manipulative Technique|BEHAVIORAL: Pain Neuroscience Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Beta Blocker De-prescription Following Coronary Artery Bypass Graft Surgery (BEEFBURGER Trial).
Status: RECRUITING
Conditions: Coronary Artery Disease|Acute Myocardial Infarction|Coronary Artery Stenosis|ST Elevation Myocardial Infarction|Non-ST Elevation Myocardial Infarction (NSTEMI)
Interventions: DRUG: De-prescribe beta blocker therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: p53 Gene in Treatment of Recurrent Ovarian Epithelial Cancer, Fallopian Tube Cancer, and Primary Peritoneal Cancer
Status: UNKNOWN
Conditions: Ovarian Epithelial Cancer|Fallopian Tube Cancer|Primary Peritoneal Cancer
Interventions: DRUG: p53 gene|DRUG: Cisplatin|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Progesterone in Treatment of Vasomotor Symptoms
Status: TERMINATED
Conditions: Menopause Related Conditions
Interventions: DRUG: Progesterone oral capsule|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Palliative Treatment of Hepatocellular Carcinoma in Patient With CHILD B Cirrhosis
Status: COMPLETED
Conditions: Hepatocellular Carcinoma|CHILD B
Interventions: DRUG: sorafenib|DRUG: Pravastatin|DRUG: Sorafenib + Pravastatin|OTHER: patients receiving best supportive care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Low, Moderate and High Carbohydrate Diet on Insulin Requirements and Metabolic Control in Type 1 Diabetes
Status: ACTIVE_NOT_RECRUITING
Conditions: Type1diabetes
Interventions: BEHAVIORAL: traditional diabetes diet|BEHAVIORAL: moderately low carbohydrate diet|BEHAVIORAL: strictly low carbohydrate diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: i2TransHealth: Interdisciplinary, Internet-based Trans Health Care
Status: COMPLETED
Conditions: Gender Dysphoria|Gender Identity Disorder|Transsexualism|Gender Identity|Gender Incongruence
Interventions: OTHER: i2TransHealth
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Use of Drug-Coated Balloon to Improve Recanalization of a Coronary Chronic Total Occlusion After Failed Angioplasty
Status: COMPLETED
Conditions: Chronic Total Occlusion
Interventions: DEVICE: Paclitaxel-coated Balloon dilation angioplasty|DEVICE: Non-coated Balloon dilation angioplasty
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety of Viusid in Patients With Hepatic Cirrhosis Secondary to Hepatitis C Virus Infection.
Status: COMPLETED
Conditions: Cirrhosis|Chronic Hepatitis C
Interventions: DIETARY_SUPPLEMENT: Viusid (nutritional supplement)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Spinal Cord Injury Model Systems (SCIMS) - Education Module
Status: RECRUITING
Conditions: Spinal Cord Injuries|Obesity|Cardiometabolic Syndrome
Interventions: BEHAVIORAL: PVA Consumer Guide|BEHAVIORAL: WebMD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of ARX788 Combined With Pyrotinib Maleate Versus TCBHP (Trastuzumab Plus Pertuzumab With Docetaxel and Carboplatin) as Neoadjuvant Treatment in HER2-positive Breast Cancer Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: HER2-positive Breast Cancer
Interventions: DRUG: ARX788|DRUG: Pyrotinib maleate|DRUG: Trastuzumab|DRUG: Pertuzumab|DRUG: Docetaxel|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of DCB Therapy for ISR Under the Guidance of QFR (UNIQUE-DCB-II Study )
Status: NOT_YET_RECRUITING
Conditions: Coronary Heart Disease
Interventions: DEVICE: drug coated balloon|DEVICE: drug eluted stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Weight and Insulin Sensitivity on Reproductive Function in PCOS
Status: TERMINATED
Conditions: Polycystic Ovary Syndrome
Interventions: DRUG: Metformin|BEHAVIORAL: Dietary Restriction|BEHAVIORAL: Exercise Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of the Levitation Knee Brace
Status: ACTIVE_NOT_RECRUITING
Conditions: Knee Osteoarthritis
Interventions: DEVICE: Levitation 2 Tri-Compartment Offloader (TCO) knee brace|DEVICE: Knee sleeve
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effectiveness of Cosopt® as First Line Therapy (MK-0507A-153)
Status: COMPLETED
Conditions: Glaucoma|Ocular Hypertension
Interventions: DRUG: dorzolamide hydrochloride (+) timolol maleate|DRUG: Comparator: dorzolamide HCl/timolol maleate + prostaglandin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: First-line Nab-paclitaxel Plus Cisplatin Plus Carilizumab in mTNBC Patients
Status: RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: nab-paclitaxel plus cisplatin plus carilizumab (AP+PD-1)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effective Dose of Dexmedetomidine for Sedation in Patients Undergoing TURP/TURB Under Spinal Anesthesia With or Without Fentanyl by Age Groups: Randomized Comparative Study
Status: COMPLETED
Conditions: Benign Prostate Hyperplasia|Bladder Tumor
Interventions: DRUG: dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Treatment Of CORONAVIRUS DISEASE 2019 (COVID-19) With Anti-Sars-CoV-2 Convalescent Plasma (ASCoV2CP)
Status: NO_LONGER_AVAILABLE
Conditions: Severe Acute Respiratory Syndrome Coronavirus 2
Interventions: BIOLOGICAL: Anti-Sars-CoV-2 Convalescent Plasma
Study Type: EXPANDED_ACCESS
Clinical trial: The Relationship Between Macular OCTA and GCIPL and Their Combinational Index Using AI
Status: UNKNOWN
Conditions: Angiography|Glaucoma, Open-Angle
Interventions: DIAGNOSTIC_TEST: Optical Coherence Tomography Angiography (OCTA)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Investigation of The Effects of Different Exercise Methods on Swallowing Function in Stroke Patients
Status: COMPLETED
Conditions: Stroke|Dysphagia|Swallowing Disorder
Interventions: OTHER: Active Comparator: Routine Exercise Group|OTHER: Experimental: PNF Exercise|OTHER: Experimental: CTAR Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Safety, Tolerability and Pharmacokinetic (PK) Study of GSK1070806 for the Prevention of Delayed Graft Function (DGF) in Adult Subjects After Renal Transplantation
Status: TERMINATED
Conditions: Kidney Transplantation (Status Post)
Interventions: BIOLOGICAL: GSK1070806|DRUG: 1) basiliximab 2) mycophenolate mofetil (MMF) OR azathioprine 3) tacrolimus 4) corticosteroids
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diagnostic Benefits of HyperQTM vs. Conventional ECG Stress Test. Comparison of HyperQ vs. Stress ECG in Women Before Angiography
Status: UNKNOWN
Conditions: Ischemic Heart Disease
Interventions: DEVICE: Exercise test with HyperQ technology
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Multicenter Study to Evaluate the Effects of a 91-Day Extended Cycle Oral Contraceptive on Hemostatic Parameters in Healthy Women
Status: COMPLETED
Conditions: Hemostasis|Oral Contraceptive
Interventions: DRUG: 91-day Levonorgestrel Oral Contraceptive|DRUG: 28-day Levonorgestrel Oral Contraceptive|DRUG: 28-day Desogestrel Oral Contraceptive
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Feasibility and Acceptability of a Complex Intervention to Improve Initial Medication Adherence
Status: COMPLETED
Conditions: Adherence, Medication
Interventions: BEHAVIORAL: Initial Medication Adherence (IMA) Intervention|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effects of Phototherapy Associated With Sprint and Squat Training on Cardiac Autonomic Modulation
Status: COMPLETED
Conditions: Phototherapy|Autonomic Nervous System|Training
Interventions: OTHER: Phototherapy|OTHER: Placebo|OTHER: Passive recovery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Mentalization-based Intervention for Children of Parent(s) With Borderline Personality Disorder
Status: RECRUITING
Conditions: Child's Internalizing and Externalizing Problems
Interventions: BEHAVIORAL: Mentalization-based treatment for children (MBT-C)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sublingual Immunotherapy of Birch Pollen Associated Apple Allergy
Status: COMPLETED
Conditions: Birch Pollen Related Apple Allergy|Birch Pollen Allergy
Interventions: DRUG: rMal d 1|DRUG: rBet v 1|OTHER: placebo drops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Reducing Stomach Acid on Post-tonsillectomy Pain
Status: TERMINATED
Conditions: Post-tonsillectomy Pain|Post-tonsillectomy Activity|Post-tonsillectomy Hydration
Interventions: DRUG: Lansoprazole|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT