pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Effects of TPV/r on the Pharmacokinetics of Carbamazepine in Healthy Adult Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Carbamazepine|DRUG: Tipranavir|DRUG: Ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Is ENI Necessary For Patients With Thoracic Esophageal Cancer After Esophagectomy And With Pathological Stage Of T1-2,N+,M0
Status: UNKNOWN
Conditions: Esophageal Squamous Cell Carcinoma
Interventions: RADIATION: Elective nodal irradiation (ENI)|OTHER: Adjuvant chemotherapy only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Aerobics on Physical and Mental Health in Polycystic Ovary Syndrome
Status: RECRUITING
Conditions: Polycystic Ovary Syndrome
Interventions: OTHER: Structured aerobics exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Histology and Ultrasound Pilot Study of HA Gels Adipose Tissue
Status: COMPLETED
Conditions: Atrophy
Interventions: DEVICE: Hyaluronic Acid filler|DEVICE: Hyaluronic Acid filler
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Ofatumumab in Treating Patients With Previously Untreated Stage II, Stage III, or Stage IV Follicular Non-Hodgkin Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: BIOLOGICAL: ofatumumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Acupuncture and Low Caloric Diet on Primary Hypothyroidism and Irregular Menstruation in Infertile Women
Status: COMPLETED
Conditions: Primary Hypothyroidism|Acupuncture|Irregular Menstruation|PCO
Interventions: DEVICE: acupuncture|DRUG: Thyroxine|DIETARY_SUPPLEMENT: low caloric diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Classroom Study to Assess the Time of Onset of Vyvanse (Lisdexamfetamine Dimesylate) in Pediatric Subjects Aged 6-12 With Attention Deficit/Hyperactivity Disorder (ADHD)
Status: COMPLETED
Conditions: ADHD
Interventions: DRUG: Vyvanse (lisdexamfetamine dimesylate)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combined Therapy in Age-Related Macular Degeneration (ARMD)
Status: COMPLETED
Conditions: Age-Related Macular Degeneration
Interventions: PROCEDURE: Low fluorescence Photodynamic therapy|PROCEDURE: core pars plana vitrectomy|DRUG: dexamethasone|DRUG: bevacizumab|PROCEDURE: core pars plana vitrectomy|DRUG: triamcincolone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral Iron for Erythropoietic Protoporphyrias
Status: COMPLETED
Conditions: Erythropoietic Protoporphyria|EPP|X-linked Protoporphyria|XLP
Interventions: DRUG: Oral Iron
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Percutaneous Acupoint Electrical Stimulation on Delirium
Status: RECRUITING
Conditions: Delirium, Postoperative
Interventions: DEVICE: Transcutaneous Electrical Acupoint Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Serum Levels of Vitamin D, Vitamin B12 and Folic Acid Among Patients With Lifelong Premature Ejaculation and Non-responding to Dapoxetine Treatment.
Status: COMPLETED
Conditions: Vitamin D, Vitamin B12 and Folic Acid Among Patients With Premature Ejaculation
Interventions: DIAGNOSTIC_TEST: Serum vitamin D, vitamin B12, folic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study Evaluating the Efficacy and the Benefit of Integrated Personalized Diabetes Management (PDM) for Diabetic Patients.
Status: COMPLETED
Conditions: Type II Diabetes Mellitus
Interventions: DEVICE: Accu-Chek Smart Pix Software|DEVICE: Accu-Chek Smart Pix readout Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Konjac-Glucomannan Fibre Blend and American Ginseng in Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DIETARY_SUPPLEMENT: American Ginseng|DIETARY_SUPPLEMENT: Konjac-glucomannan fiber blend|DIETARY_SUPPLEMENT: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study To Evaluate Efficacy, Safety And Tolerability Of Lyrica In Patients With Painful Diabetic Peripheral Neuropathy
Status: COMPLETED
Conditions: Diabetic Neuropathy, Painful
Interventions: DRUG: Pregabalin|DRUG: Placebo matched with pregabalin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: SOX Versus XELOX as Adjuvant Chemotherapy for Stage III Colorectal Cancer Patients
Status: UNKNOWN
Conditions: Colorectal Cancer Stage III|Adjuvant Chemotherapy
Interventions: DRUG: Oxaliplatin|DRUG: Tegafur，gimeracil and oteracil potassium|DRUG: Xeloda
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Clinical Trial of Difference Between Formaderm Lidocaine and Formaderm Dermal Filler Injection
Status: COMPLETED
Conditions: Dermal Fillers|Lidocaine|Hyaluronic Acid
Interventions: DEVICE: Formaderm Lidocaine|DEVICE: Formaderm Dermal Filler Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigational Agent AG-013736 In Combinations With Standard Of Care Treatments For Patient's With Advanced Solid Tumor
Status: COMPLETED
Conditions: Neoplasms
Interventions: DRUG: Axitinib + Paclitaxel + Carboplatin (Cohort 1)|DRUG: Axitinib + Paclitaxel + Carboplatin (Cohort 2)|DRUG: Axitinib + Paclitaxel + Carboplatin (Cohort 3)|DRUG: Axitinib + Paclitaxel (Cohort 4)|DRUG: Axitinib + Docetaxel + Carboplatin (Cohort 4a)|DRUG: Axitinib + Docetaxel (Cohort 5)|DRUG: Axitinib + Capecitabine (Cohort 6)|DRUG: Axitinib + Capecitabine (Cohort 7)|DRUG: Axitinib + Gemcitabine + Cisplatin (Cohort 8)|DRUG: Axitinib + Pemetrexed + Cisplatin (Cohort 9)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Renal Denervation in Patients After Acute Coronary Syndrome
Status: UNKNOWN
Conditions: Acute Coronary Syndrome|Arterial Hypertension
Interventions: PROCEDURE: Renal denervation|DRUG: Metoprolol|DRUG: Lisinopril
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Treatment for Newly Diagnosed Multiple Myeloma Patients Older Than 65 Years With Sequential Melphalan/Prednisone/Velcade (MPV) Followed by Revlimid/Low Dose Dexamethasone (Rd) Versus Alternating Velcade/Melphalan/Prednisone (MPV) With Revlimid/Low Dose Dexamethasone
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Melphalan|DRUG: Prednisone|DRUG: Velcade|DRUG: Revlimid|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Ovulation Induction Cycle Outcomes Between Early and Late Dose Increments for Low Dose Gonadotropin Step-up Protocol Among Infertile Women Diagnosed With Polycystic Ovary Syndrome: Prospective Randomised Trial
Status: UNKNOWN
Conditions: Polycystic Ovary Syndrome|Infertility, Female
Interventions: DRUG: Gonadotropin dose increment timing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Sensory Stimulation Versus Sensorimotor Therapy on Spasticity, Motor Function and Daily Activities in Stroke
Status: RECRUITING
Conditions: Stroke, Ischemic|Proprioceptive Disorders|Sensory Defect
Interventions: OTHER: exteroceptive and proprioceptive sensory stimulation training|OTHER: sensorimotor therapy group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Physical Activity Intervention for Patients Following Lumbar Spine Surgery
Status: COMPLETED
Conditions: Spinal Degenerative Disorder|Spinal Stenosis|Spondylosis
Interventions: BEHAVIORAL: Physical activity intervention|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Multicenter, Randomized, Double-Blind, Double-Dummy Trial of Azithromycin SR Compared With Levofloxacin for the Treatment of Acute Symptoms of Chronic Bronchitis
Status: COMPLETED
Conditions: Bronchitis, Chronic
Interventions: OTHER: placebo|DRUG: azithromycin SR (Zithromax; compound: CP-62,993)|OTHER: placebo|DRUG: levofloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability Evaluation of Sintilimab in Combination With Radiation in Stage IV NSCLC Patients
Status: COMPLETED
Conditions: Stage IV NSCLC
Interventions: DRUG: Sintilimab|RADIATION: stereotactic body radiation therapy|RADIATION: Low Dose Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Single Ascending Dose Trial Assessing Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ZP7570
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Dual GLP-1/GLP-2 Receptor agonists
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Suturing and Packing of Drained Abscesses
Status: COMPLETED
Conditions: Cutanoeus Abscesses
Interventions: OTHER: PRIMARY CLOSRE|OTHER: SECONDARY CLOSURE|OTHER: SPONTANEOUS HALING
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Behavioral Lifestyle Intervention on Frailty in Older Adults With Diabetes
Status: COMPLETED
Conditions: Frailty|Weight, Body|Type 2 Diabetes
Interventions: BEHAVIORAL: Lifestyle App|BEHAVIORAL: Look AHEAD behavior lifestyle intervention|BEHAVIORAL: Abbreviated Look AHEAD behavior lifestyle intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy of Functional Electrical Stimulation (FES) in Persons Receiving Botulinum Neurotoxin for Upper Extremity Spasticity
Status: COMPLETED
Conditions: Upper Extremity Spasticity|Stroke|Acquired Brain Injury
Interventions: DEVICE: Functional Electrical Stimulation (FES) through the Ness H200
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Efficacy of Cryotherapy Combined With Compression in Preventing Neuropathy
Status: RECRUITING
Conditions: Non-metastatic Breast Cancer
Interventions: DEVICE: cryotherapy alone of the upper or lower limbs|DEVICE: cryotherapy and crompression of the upper or lower limbs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Safety and Efficacy of Dual Costimulation Blockade With VIB4920 and Belatacept for Prophylaxis of Allograft Rejection in Adults Receiving a Kidney Transplant
Status: COMPLETED
Conditions: Allografts|Rejection; Transplant, Kidney|Transplant Rejection|Kidney Transplantation
Interventions: DRUG: Belatacept|DRUG: VIB4920|DRUG: Thymoglobulin|DRUG: Methylprednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Metabolic Syndrome Diagnosis and Treatment for Adults of Low Socioeconomic Status Communities
Status: UNKNOWN
Conditions: Obesity|High Blood Pressure|Hyperglycemia|Dyslipidemia
Interventions: OTHER: Healthy Lifestyle|OTHER: Placebo Comparator (Treatment of Mexican Health Minister)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Bioequivalence Study of Montelukast From Asmakast 10mg Tabs (Sandoz, Egypt) & Singulair 10mg Tabs (Merck)
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Asmakast|DRUG: Singulair
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Myocardial Salvage and Contrast Dye Induced Nephropathy Reduction by N-Acetylcystein
Status: COMPLETED
Conditions: Myocardial Infarction
Interventions: DRUG: Acetylcystein|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Use of Electrical Impedance Spectroscopy (EIS) for Early Diagnosis of Skin Damage
Status: TERMINATED
Conditions: Melanoma (Skin)|Basal Cell Carcinoma|Squamous Cell Carcinoma|Dysplastic Nevus Syndrome|Lentigo Maligna|Seborrheic Keratosis|Lichen Planus-Like Keratosis|Carcinosarcoma
Interventions: DIAGNOSTIC_TEST: Electrical Impedence Spectroscopy DermaSense
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: TI-001 (Intranasal Oxytocin) for Treatment of High Frequency Episodic Migraine and Chronic Migraine
Status: COMPLETED
Conditions: High Frequency Episodic Migraine and Chronic Migraine
Interventions: DRUG: TI-001|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial to Evaluate the Safety and Efficacy of Rreproxalap in Adults With Dry Eye Disease
Status: COMPLETED
Conditions: Dry Eye Syndromes
Interventions: DRUG: Reproxalap Ophthalmic Solution (0.25%)|DRUG: Vehicle Ophthalmic Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bevacizumab and Erlotinib Followed by Cisplatin or Carboplatin and Gemcitabine in Treating Patients With Newly Diagnosed or Recurrent Stage IIIB or Stage IV NSCLC
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DRUG: bevacizumab + erlotinib hydrochloride|DRUG: gemcitabine hydrochloride + cisplatin or carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Autologous BM-MSC Transplantation in Combination With Platelet Lysate (PL) for Nonunion Treatment
Status: UNKNOWN
Conditions: Bone Fracture
Interventions: BIOLOGICAL: Percutaneous injection|OTHER: Percutaneous injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bevacizumab Beyond Progression in Platinum Sensitive Ovarian Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Recurrent Ovarian Cancer
Interventions: DRUG: Bevacizumab|DRUG: Paclitaxel|DRUG: Carboplatin|DRUG: pegylated liposomal doxorubicin|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Anitocabtagene-autoleucel in Participants With Relapsed Refractory Multiple Myeloma
Status: ACTIVE_NOT_RECRUITING
Conditions: Relapsed and Refractory Multiple Myeloma
Interventions: DRUG: anitocabtagene-autoleucel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reduced Dose-density of Denosumab for Unresectable GCTB
Status: TERMINATED
Conditions: Bone Giant Cell Tumor
Interventions: DRUG: Denosumab 120 MG/1.7 ML Subcutaneous Solution [XGEVA]
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimization of the Primary Therapy for Patients With Hodgkin's Disease and Evaluation of PET
Status: UNKNOWN
Conditions: Hodgkin Disease
Interventions: DRUG: Combined chemotherapy (ABVD, BACOPP-D)|PROCEDURE: Radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tilting of Radioactive Plaques After Initial Accurate Placement for Treatment of Uveal Melanoma
Status: UNKNOWN
Conditions: Uveal Melanoma
Interventions: PROCEDURE: Intraoperative ultrasonography
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cyclosporine A in Combination With Abacavir Sulfate, Lamivudine, and Zidovudine and Lopinavir/Ritonavir in HIV
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Abacavir sulfate, Lamivudine, and Zidovudine|DRUG: Lopinavir/Ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating a Participatory Nutrition Education Model on Nutrition Literacy of Adolescent Girls in Rural Ghana.
Status: COMPLETED
Conditions: Malnutrition|Adolescent Development|Adolescent Behavior
Interventions: BEHAVIORAL: Participatory video
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Ciprofol Versus Propofol for Tracheal Intubation in ICU
Status: NOT_YET_RECRUITING
Conditions: Emergency Tracheal Intubation in Critically Ill Patients
Interventions: DRUG: Ciprofol|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Use of a Biological Lens of Amniotic Membrane (LV-Visio-AMTRIX) in the Treatment of Trophic Ulcers
Status: WITHDRAWN
Conditions: Corneal Ulcer|Persistent Corneal Epithelial Defect
Interventions: BIOLOGICAL: LV-Visio-AMTRIX
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Stitch Technique on the Occurrence of Incisional Hernia After Abdominal Wall Closure
Status: ACTIVE_NOT_RECRUITING
Conditions: Injury of Abdominal Wall
Interventions: DEVICE: Long stitch|DEVICE: Short Stitch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Impact of Long-term Pessary Use on Pelvic Organ Prolapse oìduring Covid-19 Pandemic in Patients Attending Surgery
Status: NOT_YET_RECRUITING
Conditions: Pelvic Organ Prolapse|Vaginal Prolapse
Interventions: PROCEDURE: Vaginal pessary before surgery for pelvic organ prolapse
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of Didanosine Use Alone or in Combination With Zidovudine in Infants Exposed to or Infected With HIV
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Zidovudine|DRUG: Didanosine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Sodium Channel Splicing in Heart Failure Trial (SOCS-HEFT) Prospective Study
Status: UNKNOWN
Conditions: Death, Sudden, Cardiac
Interventions: DEVICE: Implantable cardioverter-defibrillator (ICD)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: An Open-Label Study Examining the Long-Term Safety of Exenatide Given Twice Daily to Patients With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: exenatide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ERectile Dysfunctions, gOnadotoxicity and Sexual Health Assessment in Men With Lung Cancer
Status: RECRUITING
Conditions: NSCLC Stage IV|Sex Disorder|Hypogonadism, Male|Erectile Dysfunction
Interventions: DRUG: Alectinib|DRUG: Brigatinib|DRUG: Lorlatinib 100 mg|DRUG: Osimertinib|DRUG: Sotorasib|DRUG: Dabrafenib|DRUG: Trametinib|DRUG: Selpercatinib|DRUG: Pembrolizumab|DRUG: Cemiplimab|DRUG: Nivolumab|DRUG: Carboplatin|DRUG: Pemetrexed|DRUG: Paclitaxel
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Impact of Intermittent Hypoxia and Prednisolone on Motor Performance in Persons With SCI
Status: COMPLETED
Conditions: Spinal Cord Injuries
Interventions: OTHER: Prednisolone + Acute Intermittent Hypoxia|OTHER: Placebo + Acute Intermittent Hypoxia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tranexamic Acid in Traumatic Brain Injury
Status: RECRUITING
Conditions: Inflammatory Response
Interventions: OTHER: Saline|DRUG: Tranexamic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Kinect-based Versus Tablet-based Cognitive Training: a Pilot Study With Psychiatric Patients
Status: COMPLETED
Conditions: Psychiatric Disorder
Interventions: PROCEDURE: Kinect-based cognitive training|PROCEDURE: Tablet-based cognitive training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Influence of Oxytocin on Socio-communicative Sensitivity
Status: COMPLETED
Conditions: Oxytocin
Interventions: DRUG: Oxytocin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Topical Sulforaphane on Skin Aging and With Ultraviolet and Visible Light Exposure
Status: RECRUITING
Conditions: Skin Aging
Interventions: DRUG: Sulforaphane (broccoli sprout extract)|RADIATION: UV or visible light
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Trial of IW-1701 (A Stimulator of Soluble Guanylate Cyclase (sGC)) in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: IW-1701|DRUG: Matching Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Alemtuzumab (CAMPATH 1H) Associated to G-CSF in Adult Patients With Refractory Acute Lymphocytic Leukemia
Status: COMPLETED
Conditions: Acute Lymphocytic Leukemia
Interventions: DRUG: Alemtuzumab (CAMPATH 1H) associated to G-CSF
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Using Self-Motivating Messages to Encourage People to Exercise More
Status: COMPLETED
Conditions: Physical Activity
Interventions: BEHAVIORAL: Drafting Motivational Messages|BEHAVIORAL: Control Reminders|BEHAVIORAL: Treatment Reminders
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy Study of Diacerein on Glycemic Control and Liver Fat in Type 2 Diabetes Subjects
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Non-alcoholic Fatty Liver Disease
Interventions: DRUG: Diacerein|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Exploration of the VOLATOLOM in the Stable Severe COPD (Chronic Obstructive Pulmonary Disease)
Status: UNKNOWN
Conditions: Chronic Obstructive Pulmonary Disease Severe
Interventions: DEVICE: VOC analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study Evaluating the Safety of ABT-263 in Combination With Etoposide/Cisplatin in Subjects With Cancer
Status: COMPLETED
Conditions: Solid Tumors
Interventions: DRUG: ABT-263|DRUG: etoposide/cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SUV on 68Ga-DOTATATE PET/CT and Ki-67 Index in Neuro-Endocrine Tumors
Status: COMPLETED
Conditions: Neuroendocrine Tumors
Interventions: DRUG: 68Ga-DOTATATE PET/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Tele-rehabilitation Program: An Innovative and Sustainable Early Intervention Service for Children With Autism Spectrum Disorders
Status: ACTIVE_NOT_RECRUITING
Conditions: Autism Spectrum Disorder
Interventions: BEHAVIORAL: Foundational Skills Curriculum|BEHAVIORAL: Foundational Skills Curriculum - Telerehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: rVA576 (Coversin) Long Term Safety and Efficacy Surveillance Study
Status: TERMINATED
Conditions: Paroxysmal Nocturnal Hemoglobinuria
Interventions: DRUG: rVA576 (Coversin)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Decreasing ED Utilization by Nudging Patients to Call Their Providers
Status: COMPLETED
Conditions: Emergency Treatment|Telephone Hotlines
Interventions: BEHAVIORAL: message|BEHAVIORAL: provider|BEHAVIORAL: tele-nurse
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Low Level Laser Therapy Associated With Exercise in Subacromial Impingement Syndrome
Status: COMPLETED
Conditions: Subacromial Impingement Syndrome
Interventions: RADIATION: Laser|OTHER: EXE|RADIATION: Laser + EXE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Reducing Sedentary Behavior Among Prostate Cancer Survivors on Androgen Deprivation Therapy
Status: COMPLETED
Conditions: Prostate Cancer|Prostate Neoplasm|Cancer|Sedentary Lifestyle
Interventions: OTHER: RiseTx
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Clinical Evaluation Of Dental Implants Stability Placed In Healed Bony Sites Following Over-drilling Compared To Conventional-Drilling Protocol
Status: UNKNOWN
Conditions: Crestal Bone Resorption|Implant Primary Stability|Implant Osseointegration
Interventions: PROCEDURE: implant site over drilling protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: SIT LESS 3: The Effect of Low Intensity Physical Activity on Insulin Sensitivity, Mood and Cognitive Performance
Status: COMPLETED
Conditions: Overweight|Obesity
Interventions: BEHAVIORAL: Physical activity regime
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Calf Muscle Strength and Standing Efficiency in Children With Spastic Diplegia
Status: COMPLETED
Conditions: Cerebral Palsy
Interventions: OTHER: Strengthening exercise + Electrical stimulation of calf muscle|OTHER: selected physical therapy program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Liuzijue Exercise Versus Tai Chi Chuan Exercise in Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: OTHER: Liuzijue Exercise|OTHER: Tai Chi Chuan Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Standardized Olive Leaf Capsules; as a Co-therapy in the Treatment of COVID-19 Patients
Status: COMPLETED
Conditions: Covid19|COVID-19 Respiratory Infection|Symptoms and Signs|COVID-19 Acute Bronchitis|Disseminated Intravascular Coagulation
Interventions: DIETARY_SUPPLEMENT: Nusapure standardized olive leaves capsule, 750 mg (50% oleuropein)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Nimotuzumab Plus Paclitaxel and Cisplatin as 1st Line Treatment for Esophageal Squamous Cell Cancer
Status: UNKNOWN
Conditions: Esophageal Squamous Cell Cancer
Interventions: DRUG: Nimotuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Polyphenols and Endothelial Function
Status: TERMINATED
Conditions: Sedentary Subjects
Interventions: DIETARY_SUPPLEMENT: juice rich in polyphenols|DIETARY_SUPPLEMENT: juice poor in polyphenols
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Open-Label Extension Study of Ubenimex in Patients With Pulmonary Arterial Hypertension (WHO Group 1)
Status: TERMINATED
Conditions: Pulmonary Arterial Hypertension
Interventions: DRUG: ubenimex
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Aging Brain and Cognition: Contribution of Vascular Injury, Amyloid Plaque and Tau Protein to Cognitive Dysfunction After Stroke
Status: COMPLETED
Conditions: Post-stroke Dementia|Vascular Mild Cognitive Impairment
Interventions: DRUG: THK-5351|DRUG: AV-45
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Von Willebrand Factor Point-of-care Testing to Improve Minimally Invasive TAVI Outcomes
Status: RECRUITING
Conditions: Aortic Valve Stenosis|Aortic Valve Insufficiency
Interventions: DIAGNOSTIC_TEST: CT-ADP performed during TAVI procedure|OTHER: No CT-ADP performed during TAVI procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Safety and Tolerability, Pharmacodynamic Effects and Exploratory Efficacy of a Vaccine Against Essential Hypertension
Status: COMPLETED
Conditions: Hypertension
Interventions: BIOLOGICAL: CYT006-AngQb|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 4SCAR-CD44v6 T Cell Therapy Targeting Cancer
Status: UNKNOWN
Conditions: Cancers Which Are CD44v6 Positive
Interventions: BIOLOGICAL: CD44v6-specific CAR gene-engineered T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study on Immediate Placement to Evaluate Astra Tech Osseospeed Implants in an Immediate Loading Protocol in Extraction Sockets and Healed Ridges
Status: COMPLETED
Conditions: Dental Implants
Interventions: PROCEDURE: Immediate implants
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Freiburg ZNS-NHL Study
Status: UNKNOWN
Conditions: Primary Non Hodgkin Lymphoma of the Central Nervous System
Interventions: DRUG: methotrexate|DRUG: Rituximab|DRUG: Cytarabine|DRUG: Thiotepa|DRUG: Carmustin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: UC Health Care Planning Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Advance Care Planning|Advance Directives|Advanced Cancer
Interventions: BEHAVIORAL: Advance directive|BEHAVIORAL: Prepare|BEHAVIORAL: Facilitator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Donor Regulatory T-cells for cGVHD in Patients Who do Not Obtain Complete Remission With Ruxolitinib
Status: RECRUITING
Conditions: Chronic Graft vs Host Disease
Interventions: BIOLOGICAL: Regulatory T-cell enriched infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sotorasib in Previously Treated Locally Advanced or Metastatic NSCLC Subjects With Mutated KRAS p.G12C
Status: RECRUITING
Conditions: KRAS P.G12C|Non Small Cell Lung Cancer
Interventions: DRUG: Sotorasib 120Mg Tab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Magen Haim Project - Assessing Hand Hygiene Formulas
Status: UNKNOWN
Conditions: Comparing Use of Hand Hygiene Products
Interventions: OTHER: AniosGel 85 NPC|OTHER: Softa-Man (Braun)|OTHER: Septol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of a Topical Ketamine on Acute and Chronic Pain, Dose Finding
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: group (A)|DRUG: group (B)|DRUG: group (c)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Mitoxantrone for Venetoclax Resistant Acute Myeloid Leukemia
Status: RECRUITING
Conditions: Leukemia|Myeloid Leukemia|Monocytic Leukemia
Interventions: DRUG: Venetoclax|DRUG: Azacitidine|DRUG: Mitoxantrone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Mindfulness-Based Stress Reduction on Knee Osteoarthritis
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: BEHAVIORAL: Mindfulness-Based Stress Reduction|BEHAVIORAL: Health Enhancement Program
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Gemcitabine Plus Rapamycin Versus Gemcitabine to Treat Advanced Soft Tissue Sarcoma
Status: COMPLETED
Conditions: Advanced Soft Tissue Sarcoma
Interventions: DRUG: Gemcitabine + Rapamycin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neural Circuits in Women With Abuse and Posttraumatic Stress Disorder
Status: COMPLETED
Conditions: PTSD
Interventions: DRUG: Placebo|DRUG: Paroxetine|OTHER: Positron Emission Tomography (PET) Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Prevention of COVID-19 withVYD222 in Adults With Immune Compromise and in Participants Aged 12 Years or Older Who Are at Risk of Exposure to SARS-CoV-2
Status: ACTIVE_NOT_RECRUITING
Conditions: COVID-19|SARS-CoV-2
Interventions: DRUG: VYD222 (pemivibart)|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Rituximab as Second Line Treatment for ITP
Status: COMPLETED
Conditions: Immune Thrombocytopenia (ITP)
Interventions: DRUG: Rituximab (Mabthera)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study in a Company in Maine-et-Loire to Evaluate the Feasibility, Acceptability, and Impact on the Participation Rate of Awareness of Colorectal Cancer Screening by Occupational Health Teams
Status: UNKNOWN
Conditions: Colorectal Cancer
Interventions: OTHER: awareness campaign
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Evaluation for the Characterization of the Safety Profile of the DiamondTemp™ System for Fast Treatment of Patients With Atrial Fibrillation
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DEVICE: DiamondTemp Cardiac Ablation System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vorinostat and Trastuzumab in Treating Patients With Metastatic or Locally Recurrent Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer|Male Breast Cancer|Recurrent Breast Cancer|Stage IIIB Breast Cancer|Stage IIIC Breast Cancer|Stage IV Breast Cancer
Interventions: DRUG: vorinostat|DRUG: trastuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Safety and Efficacy of Novel Immunotherapy Combinations in Patients With Triple Negative Breast Cancer (TNBC).
Status: TERMINATED
Conditions: Triple Negative Breast Cancer (TNBC)
Interventions: BIOLOGICAL: spartalizumab|BIOLOGICAL: LAG525|DRUG: NIR178|DRUG: capmatinib|BIOLOGICAL: MCS110|BIOLOGICAL: canakinumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Test the Safety and Tolerability of PF-07220060 in Participants With Advance Solid Tumors
Status: RECRUITING
Conditions: Liposarcoma|Prostate Cancer|Breast Neoplasms|Adenocarcinoma of Lung
Interventions: DRUG: PF-07220060|COMBINATION_PRODUCT: Letrozole|COMBINATION_PRODUCT: Fulvestrant|DRUG: Midazolam|COMBINATION_PRODUCT: Enzalutamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Integrating CHWs Into Prenatal Care for Maternal Smoking Cessation
Status: RECRUITING
Conditions: Tobacco Use|Tobacco Use Cessation|Tobacco Use in Childbirth
Interventions: BEHAVIORAL: HCP-CHW Integration into Prenatal Care for Smoking Cessation|OTHER: Control Arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Homeopathic Treatment of Premenstrual Syndrome
Status: UNKNOWN
Conditions: Premenstrual Syndrome-PMS
Interventions: DRUG: Natrum muriaticum 30C|DRUG: Lachesis 30C|DRUG: Sepia 30C|DRUG: Nux vomica 30C|DRUG: Pulsatilla 30C|DRUG: Folliculinum 30C|DRUG: Placebo Natrum muriaticum|DRUG: Placebo Lachesis|DRUG: Placebo Sepia|DRUG: Placebo Nux vomica|DRUG: Placebo pulsatilla|DRUG: Placebo Folliculinum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tolerance and Utilization of Polydextrose, Inulin, and Soluble Corn Fiber
Status: COMPLETED
Conditions: Tolerance
Interventions: OTHER: polydextrose|OTHER: soluble corn fiber
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Epigenetics in PostOperative Pediatric Emergence Delirium
Status: COMPLETED
Conditions: Emergence Delirium|Postoperative Complications|DNA Methylation
Interventions: DRUG: Sevoflurane|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: A Study to Assess the Effect of Repeat Doses of GSK962040 on the Pharmacokinetics of L-DOPA in Subjects With Parkinson's Disease Exhibiting Delayed Gastric Emptying
Status: COMPLETED
Conditions: Gastroparesis
Interventions: DRUG: GSK962040 (25 mg tablet)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: MoviPrep® Versus HalfLytely®, Low-VolUme PEG Solutions for Colon Cleansing: An InvesTigator-blindEd, Randomized, Trial
Status: COMPLETED
Conditions: Colonoscopy
Interventions: OTHER: MoviPrep Kit|OTHER: HalfLytely and Bisacodyl Tablets Bowel Prep Kit
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Electrophysiological Changes Based on the Palmaris Longus
Status: UNKNOWN
Conditions: Palmaris Longus Muscle, Absence of|Carpal Tunnel Syndrome|EMG Syndrome
Interventions: DIAGNOSTIC_TEST: EMG|DIAGNOSTIC_TEST: Palmaris Longus Test
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Evaluate the Safety, Tolerability, Pharmacokinetic Properties and Immunogenicity of 9MW3811 in Healthy Subjects
Status: RECRUITING
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: DRUG: 9MW3811 Injection|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Bio-psycho-social Exercise Program (RÜCKGEWINN) for Chronic Low Back Pain in Rehabilitation Aftercare
Status: COMPLETED
Conditions: Low Back Pain
Interventions: OTHER: educational booklet|OTHER: IRENA|OTHER: RÜCKGEWINN
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Modifications in the Anaerob Threshold in Cyclists by Consuming Docosahexaenoic Acid (DHA)
Status: COMPLETED
Conditions: Performance
Interventions: DIETARY_SUPPLEMENT: docosahexaenoic acid|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Best Supportive Care With or Without Low Dose Whole Lung Radiation Therapy for the Treatment of COVID-19
Status: ACTIVE_NOT_RECRUITING
Conditions: Pneumonia|Severe Acute Respiratory Syndrome|Symptomatic COVID-19 Infection Laboratory-Confirmed
Interventions: OTHER: Best Practice|RADIATION: Low Dose Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Long-term Effectiveness of High Frequency Repetitive Transcranial Magnetic Stimulation of Stroke (RAICup)
Status: TERMINATED
Conditions: Nervous System Diseases|Stroke|Cerebrovascular Disorders|Brain Infarction|Brain Ischemia
Interventions: DEVICE: repetitive transcranial magnetic stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Eplerenone as a Supplement to Epidural Steroid Injections
Status: WITHDRAWN
Conditions: Degenerative Intervertebral Discs|Sciatic Radiculopathy|Low Back Pain
Interventions: DRUG: Eplerenone 50 Mg Tab|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, and Anti-Tumor Activity of AFM24 in Combination With SNK01 in Subjects With Advanced/Metastatic EGFR-Expressing Cancers
Status: TERMINATED
Conditions: Squamous Cell Carcinoma of Head and Neck|Carcinoma, Non-Small-Cell Lung|Colorectal Neoplasms|Advanced Solid Tumor|Refractory Tumor|Metastatic Tumor
Interventions: DRUG: AFM24|BIOLOGICAL: SNK01
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Quadruple Therapy for Triple Therapy Resistant Helicobacter Pylori Infection
Status: COMPLETED
Conditions: Treatment of Helicobacter Pylori
Interventions: DRUG: Augmentin (Amoxicillin-clavulanic)|DRUG: Furoxone (furazolidone)|DRUG: Cebes (colloidal bismuth subcitrate)|DRUG: Esso (esomeprazole)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Anaesthesia Costs and Recovery Profiles
Status: COMPLETED
Conditions: Anaesthesia
Interventions: DRUG: Sevoflurane group A|DRUG: Sevoflurane group B|DRUG: Propofol group C|DRUG: Propofol group D
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Asfotase Alfa in Adolescents and Adults With Hypophosphatasia (HPP)
Status: COMPLETED
Conditions: Hypophosphatasia
Interventions: DRUG: asfotase alfa|DRUG: asfotase alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT