pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: MRI-guided Focused Ultrasound : Feasibility Study for the Treatment of Bone Metastases and osteoïd Osteoma
Status: RECRUITING
Conditions: Painful Bone Metastases|Superficial Osteoid Osteoma
Interventions: DEVICE: UFOGUIDE "patient transducer"
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Evaluation of Rebamipide and Rabeprazole Effect Associated or Not to Prevent Naproxen-induced Gastric Lesions
Status: COMPLETED
Conditions: Gastric Lesion
Interventions: DRUG: 550 mg naproxen + 300 mg rebamipide + 20 mg rabeprazole.|DRUG: 550 mg naproxen + placebo + 20 mg rabeprazole|DRUG: 550 mg naproxen + 300 mg rebamipide + placebo|DRUG: 550 mg naproxen + placebo + placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate Safety of Single Doses of BMS-986177 in Patients With End Stage Renal Disease (ESRD) Treated With Hemodialysis
Status: COMPLETED
Conditions: Antithrombotic
Interventions: DRUG: Enoxaparin|DRUG: unfractionated heparin (UFH)|DRUG: BMS-986177
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pegfilgrastim on Day +3 Compared to Day +1 After Salvage Chemotherapy for Patients With Refractory or Relapsed Aggressive Lymphoma
Status: UNKNOWN
Conditions: Lymphoma|Neutropenia
Interventions: DRUG: Pegfilgrastim
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pharmacokinetic Study of Capecitabine After Total Gastrectomy for Stomach Adenocarcinoma
Status: TERMINATED
Conditions: Adenocarcinoma of the Stomach
Interventions: DRUG: capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Dose Ranging Study of RPC4046 in Eosinophilic Esophagitis
Status: COMPLETED
Conditions: Eosinophilic Esophagitis
Interventions: DRUG: RPC4046|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare Two Techniques for Articular Cartilage Repair: Cultured Chondrocytes Vs. Cultured BMAC
Status: UNKNOWN
Conditions: The Focus of the Study is the Quality and Amount of Regenerated Articular Cartilage.
Interventions: PROCEDURE: Cultured Chondrocytes|PROCEDURE: Cultured BMAC
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Biomarkers of Response of TBS in Treatment Resistant Depression
Status: RECRUITING
Conditions: Resistant Depression, Treatment|Bipolar Depression
Interventions: DEVICE: Theta Burst Transcranial Magnetic Bilateral Stimulation|DEVICE: Theta Burst Transcranial Magnetic Sham Stimulation|DEVICE: Theta Burst Transcranial Magnetic Unilateral Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Mitoxantrone Hydrochloride Liposome Combined With Rituximab and Lenalidomide (M+R2) in Patients With Relapsed and Refractory Diffuse Large B-Cell Lymphoma
Status: NOT_YET_RECRUITING
Conditions: Diffuse Large B-cell Lymphoma
Interventions: DRUG: Mitoxantrone Hydrochloride Liposome|DRUG: Rituximab|DRUG: Lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pembrolizumab Plus Neoadjuvant Chemotherapy vs. Neoadjuvant Chemoradiotherapy for Locally Advanced ESCC (KEYSTONE-002)
Status: RECRUITING
Conditions: Esophageal Squamous Cell Carcinoma
Interventions: BIOLOGICAL: Pembrolizumab|DRUG: Paclitaxel|DRUG: Cisplatin|RADIATION: neoadjuvant chemoradiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Minimally Invasive Surgery vs Standard Posterior Approach in the Treatment of Developmental Idiopathic Scoliosis
Status: RECRUITING
Conditions: Adolescent Idiopathic Scoliosis
Interventions: PROCEDURE: mini invasive scoliosis surgery|PROCEDURE: posterior spinal fusion technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hypothalamic Obesity Following Craniopharyngioma Surgery: A Pilot Trial of Combined Metformin and Diazoxide Therapy
Status: COMPLETED
Conditions: Hypothalamic Obesity
Interventions: DRUG: Diazoxide|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Developing the Precision Nursing Education Program to Young Colorectal Cancer Survivors
Status: NOT_YET_RECRUITING
Conditions: Depression
Interventions: BEHAVIORAL: 8-weeks's on-line precision nursing education program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy and Safety Assessment of T4090 Ophthalmic Solution Versus Rhopressa® Ophthalmic Solution in Patients With Open-angle Glaucoma or Ocular Hypertension
Status: RECRUITING
Conditions: Glaucoma|Ocular Hypertension
Interventions: DRUG: T4090 0.2%|DRUG: T4090 0.3%|DRUG: Rhopressa®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Use of Penile Vibratory Stimulation to Decrease Spasticity Following Spinal Cord Injury
Status: COMPLETED
Conditions: Spinal Cord Injury|Muscle Spasticity
Interventions: PROCEDURE: Penile Vibratory Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Postoperative Pain After Conservative Root Canal Preparation
Status: ACTIVE_NOT_RECRUITING
Conditions: Periapical Diseases|Periapical Periodontitis|Postoperative Pain|Pulp Necroses|Flare Up, Symptom
Interventions: PROCEDURE: Root Canal Treatment with ProTaper Next Nickel-Titanium File (PTN)|PROCEDURE: Root Canal Treatment withTruNatomy Nickel-Titanium File (TN)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Improving Diabetes Care and Outcomes on the South Side of Chicago
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: BEHAVIORAL: Patient Activation|BEHAVIORAL: Provider Training|BEHAVIORAL: Quality Improvement|BEHAVIORAL: Community Outreach
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: NY-ESO-1 TCR （TAEST16001）for Patients With Advanced NSCLC
Status: UNKNOWN
Conditions: Lung Cancer, Nonsmall Cell, Recurrent
Interventions: DRUG: Cyclophosphamide and Fludarabine|BIOLOGICAL: Anti-NY-ESO-1 TCR transduced T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Ketone Supplementation on Acute Alcohol Withdrawal
Status: ENROLLING_BY_INVITATION
Conditions: Alcohol Use Disorder|Alcohol Withdrawal|Alcohol Dependence|Ketosis
Interventions: DIETARY_SUPPLEMENT: Kenetik; Ketone Concentrate|DIETARY_SUPPLEMENT: Isocaloric dextrose placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Clinical Study of Intravenous Immunoglobulin
Status: COMPLETED
Conditions: Immunologic Deficiency Syndromes
Interventions: DRUG: Immune Globulin Intravenous (Human) Omr-IgG-am IGIV
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Dalantercept in Treating Patients With Recurrent Ovarian Epithelial, Fallopian Tube, or Primary Peritoneal Cavity Cancer
Status: COMPLETED
Conditions: Recurrent Fallopian Tube Carcinoma|Recurrent Ovarian Carcinoma|Recurrent Primary Peritoneal Carcinoma
Interventions: BIOLOGICAL: Dalantercept|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Glycemic Response After Palaeolithic-type Meals
Status: COMPLETED
Conditions: Glycemic Index of a Meal
Interventions: OTHER: Palaeolithic meal 1|OTHER: Palaeolithic meal 2|OTHER: Reference meal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Conversational AI System to Enhance Knowledge About Vaccines and Promote Vaccination
Status: COMPLETED
Conditions: Vaccination Hesitancy
Interventions: DEVICE: Conversational AI system|OTHER: Printed educational Brochure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Metformin for Overweight & OBese ChILdren and Adolescents With BDS Treated With SGAs
Status: COMPLETED
Conditions: Bipolar Disorder
Interventions: DRUG: Metformin|BEHAVIORAL: healthy lifestyle intervention (LIFE)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Evaluation of Clotting Factor Activity Before and After Total Hip Arthroplasty
Status: COMPLETED
Conditions: Arthroplasty, Replacement|Coagulation Factors
Interventions: DIAGNOSTIC_TEST: analysis of the concentration of the clotting factors in patients who underwent primary hip arthroplasty
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Novel Shoulder Rehabilitation Program (SPARS-REHAB)
Status: ACTIVE_NOT_RECRUITING
Conditions: Rotator Cuff Pathology
Interventions: DEVICE: Smart Physiotherapy Activity Recognition System (SPARS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Open-Label, Phase I, Escalating Dose Study to Evaluate the Safety, Tolerability, and Pharmacodynamics of PDS0101
Status: COMPLETED
Conditions: High-risk HPV Infection and Biopsy-proven CIN1
Interventions: BIOLOGICAL: R-enantiomer of 1,2-dioleoyl-3-trimethylammonium-propane chloride + Peptides from HPV-16 E6 and E7
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Targeted Melanoma Detection With Skin Self-Examination During COVID-19 Restricted Physician Access
Status: COMPLETED
Conditions: Melanoma
Interventions: BEHAVIORAL: SSE educational intervention|BEHAVIORAL: Active control:Healthy Living
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Impact of the Nutritional Product PTM202 on Acute and Long-Term Recovery From Childhood Diarrheal Disease
Status: COMPLETED
Conditions: Diarrhea
Interventions: DIETARY_SUPPLEMENT: PTM202|DIETARY_SUPPLEMENT: Enfamil Puramino
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Cosmetic Therapy on Self-esteem and Depression for Elderly Residents in Long-Term Care Institutions
Status: COMPLETED
Conditions: Long-Term Care|Aged
Interventions: BEHAVIORAL: Cosmetic therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Psychosocial Treatment for Attention Deficit Hyperactivity Disorder in Adults
Status: COMPLETED
Conditions: Attention Deficit Disorder With Hyperactivity
Interventions: BEHAVIORAL: Meta-Cognitive Therapy|BEHAVIORAL: Supportive Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dexamethasone and Respiratory Function After Mastectomy
Status: COMPLETED
Conditions: Respiratory; Disorder, Functional, Impaired
Interventions: DRUG: Intravenous Dexamethasone|DRUG: intravenous salin water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Pilot Study of the Effect of Liraglutide 3.0 mg on Weight Loss and Gastric Functions in Obesity
Status: COMPLETED
Conditions: Obesity
Interventions: DRUG: Liraglutide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Refractory Ascitis Diagnosis by the Study of Labelled Albumin Pharmacokinetics
Status: UNKNOWN
Conditions: Refractory Ascites in Patients With Cirrhosis
Interventions: RADIATION: labelled human serumalbumin (125-I, Séralb®CisBio)|RADIATION: labelled albumin (99m-Tc, Vasculocis®, Cisbio)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Aprepitant on Cyclophosphamide Pharmacokinetics in Patients With Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer|Nausea and Vomiting
Interventions: DRUG: aprepitant|DRUG: cyclophosphamide|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intercostal Nerve Cryoablation Versus Epidural Analgesia for Nuss Repair of Pectus Excavatum
Status: RECRUITING
Conditions: Pectus Excavatum|Funnel Chest
Interventions: PROCEDURE: Intercostal nerve cryoablation|DRUG: Thoracic epidural analgesia (continuous infusion with sufentanyl (1 µg/ml) and bupivacaine (1.25 mg/ml))|DRUG: Intercostal nerve block (single shot bupivacaine (1.25 mg/ml))|DRUG: Opioids (oxycodone with prolonged discharge 10 mg PO every 12 hours and oxycodone 5 mg every 6 hours, as needed)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study to Assess the Safety and Effectiveness of Palivizumab Administered to Children at High Risk of Severe Respiratory Syncytial Virus (RSV) Infection in the Russian Federation and the Republic of Belarus
Status: COMPLETED
Conditions: Respiratory Syncytial Virus (RSV)
Interventions: DRUG: Palivizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Feasibility of St. Mark's Electrode for the Hypoglossal Nerve and Cortico-lingual Pathway Study
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DIAGNOSTIC_TEST: Hypoglossal nerve conduction study|DIAGNOSTIC_TEST: Transcranial magnetic stimulation of hypoglossal nerve
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of VX-661 Alone and in Combination With Ivacaftor in Subjects Homozygous or Heterozygous to the F508del-Cystic Fibrosis Transmembrane Conductance Regulator(CFTR) Mutation
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: VX-661|DRUG: Ivacaftor|DRUG: Placebo matched to VX-661|DRUG: Placebo matched to ivacaftor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment With Intravitreal Aflibercept Injection For Proliferative Diabetic Retinopathy, The A.C.T Study
Status: COMPLETED
Conditions: Proliferative Diabetic Retinopathy
Interventions: DRUG: Intravitreal Aflibercept Injection (IAI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of the Combination of Simvastatin Plus Rifaximin in Patients With Decompensated Cirrhosis to Prevent ACLF Development
Status: COMPLETED
Conditions: Liver Cirrhoses
Interventions: DRUG: Simvastatin|DRUG: Rifaximin|DRUG: Placebo of Simvastatin|DRUG: Placebo of Rifaximin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Arginine in Treating Patients With Anti-VEGF Induced Kidney Injury
Status: WITHDRAWN
Conditions: Drug-Induced Nephropathy|Hypertension|Proteinuria
Interventions: DIETARY_SUPPLEMENT: Arginine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Efficacy and Safety of Aliskiren Alone and in Combination With Amlodipine in Essential Hypertension
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Placebo|DRUG: Aliskiren 150 mg tablet|DRUG: Aliskiren 300 mg tablet|DRUG: Amlodipine 5 mg capsule|DRUG: Amlodipine 10 mg capsule|DRUG: Aliskiren/amlodipine 150/5 mg tablet|DRUG: Aliskiren/amlodipine 150/10 mg tablet|DRUG: Aliskiren/amlodipine 300/5 mg tablet|DRUG: Aliskiren/amlodipine 300/10 mg tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Role of Chronotropic Incompetence in Heart Failure With Normal Ejection Fraction (HFNEF)
Status: COMPLETED
Conditions: Heart Failure
Interventions: DRUG: Ivabradine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Noninvasive Brain Stimulation for Stroke
Status: SUSPENDED
Conditions: Stroke
Interventions: DEVICE: tdcs (ELDITH, Neuroconn, Ilmenau, Germany)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized, Double-Blind Study Comparing Dexelvucitabine (DFC) to Lamivudine (3TC) in Subjects With Resistance to NRTIs, PIs, and NNRTIs
Status: TERMINATED
Conditions: HIV Infections|Human Immunodeficiency Virus
Interventions: DRUG: Dexelvucitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Recovering Arm Function in Chronic Post-stroke Patients Using Combined HD-tDCS and Virtual Reality Therapy
Status: RECRUITING
Conditions: Chronic Post Stroke Individuals
Interventions: DEVICE: HD-tDCS|DEVICE: Sham HD-tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Silica Gel Fiber Wound Dressing for Chronic Venous Leg Ulcers
Status: TERMINATED
Conditions: Venous Ulcer
Interventions: DEVICE: Silica Gel Fiber|DEVICE: Standard-of-Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Volasertib + Decitabine in Patients With Acute Myeloid Leukemia (AML)
Status: TERMINATED
Conditions: Leukemia, Myeloid, Acute
Interventions: DRUG: decitabine iv|DRUG: volasertib iv infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Balanced Solution Versus Saline in Intensive Care Study
Status: COMPLETED
Conditions: Critical Illness|Acute Kidney Injury
Interventions: DRUG: Plasma-Lyte|DRUG: Saline 0.9%|OTHER: Slow infusion speed|OTHER: Fast Infusion Speed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Endometrial Volume as a Predictor of Endometrial Pathology in Perimenopausal Uterine Bleeding Endometrial Volume as a Predictor of Endometrial Pathology in Perimenopausal Uterine Bleeding
Status: UNKNOWN
Conditions: Endometrial Disorder
Interventions: DIAGNOSTIC_TEST: endometrial volume 2D TVS
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Iseganan Hydrochloride in Preventing Oral Mucositis in Patients Who Are Undergoing Radiation Therapy for Head and Neck Cancer
Status: UNKNOWN
Conditions: Head and Neck Cancer|Oral Complications of Radiation Therapy|Radiation Toxicity
Interventions: DRUG: iseganan HCl oral solution|PROCEDURE: management of therapy complications
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety of Cetuximab and Oxaliplatin/5-FU/FA/Irinotecan in First-Line Treatment of Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: Cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treating Violence-Prone Substance Use Disorder Patients
Status: COMPLETED
Conditions: Substance-related Disorders|Violence
Interventions: BEHAVIORAL: Interpersonal Violence Prevention Intervention|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Compare Bosutinib To Imatinib In Subjects With Newly Diagnosed Chronic Phase Philadelphia Chromosome Positive CML
Status: COMPLETED
Conditions: Chronic Myeloid Leukemia
Interventions: DRUG: Bosutinib|DRUG: imatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect and Safety Study of Atorvastatin to Treat Chronic Subdural Hematoma
Status: COMPLETED
Conditions: Chronic Subdural Hematoma
Interventions: DRUG: Atorvastatin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Greater Occipital Nerve Block for Migraine Prophylaxis
Status: COMPLETED
Conditions: Migraine Headache
Interventions: DRUG: bupivicaine|DRUG: normal saline|DRUG: methylprednisolone|DRUG: lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Pre-operative SRS or Post-operative SRS in Treating Cancer Patients With Brain Metastases
Status: RECRUITING
Conditions: Malignant Neoplasm|Metastatic Malignant Neoplasm in the Brain
Interventions: OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration|RADIATION: Stereotactic Radiosurgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Single and Combination Diuretics in Low-Renin Hypertension
Status: UNKNOWN
Conditions: Hypertension
Interventions: DRUG: Hydrochlorthiazide|DRUG: Amiloride|DRUG: Hydrochlorthiazide and Amiloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing Mobile Health Strategies to Improve Pre-exposure Prophylaxis Use (PrEP) for HIV Prevention
Status: UNKNOWN
Conditions: HIV Infections|Sexually Transmitted Diseases
Interventions: OTHER: PrEPmate|DEVICE: Dot Diary
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Definitive Concurrent Chemoradiotherapy With Docetaxel Plus Cisplatin Versus 5-fluorouracil Plus Cisplatin in Patients With Esophageal Squamous Cell Carcinoma
Status: UNKNOWN
Conditions: Esophageal Neoplasm|Chemoradiation
Interventions: DRUG: Docetaxel|DRUG: Fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Ready and Healthy for Kindergarten Study
Status: ENROLLING_BY_INVITATION
Conditions: Parenting|Language Development|Literacy|Health Behavior
Interventions: BEHAVIORAL: Family Wellness Program (FWP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of TL-925 Ophthalmic Emulsion as a Treatment for Dry Eye Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Dry Eye Disease
Interventions: DRUG: TL-925|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: R101933 Combined With Chemotherapy in Treating Patients With Metastatic Breast Cancer That Has Not Responded to Previous Chemotherapy
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: docetaxel|DRUG: laniquidar|DRUG: paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Comparison of Surveillance Versus Aortic Endografting for Small Aneurysm Repair
Status: TERMINATED
Conditions: Aortic Aneurysm, Abdominal|Endovascular
Interventions: PROCEDURE: EVAR (Endovascular repair of Abdominal Aortic aneurysm)|PROCEDURE: Surveillance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intervention for Pregnancy Related Pain
Status: COMPLETED
Conditions: Other Specified Pregnancy-Related Conditions
Interventions: OTHER: Mulligan Concept Intervention|OTHER: Sham Mulligan Concept Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ethanol-Free Clobetasol Propionate Foam 0.05% (Olux-E Foam) vs Vehicle Foam in the Treatment of Chronic Hand Dermatitis.
Status: COMPLETED
Conditions: Dermatitis, Chronic
Interventions: DRUG: clobetasol propionate 0.05%|DRUG: Vehicle / Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Managing Type 1 and High Risk Type 2 Diabetes in the Hospital Setting: Glucose as a Vital Sign
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1|Diabetes Mellitus, Type 2
Interventions: DEVICE: Real-time CGM data
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Efficacy and Safety of BIA 9-1067 in Idiopathic Parkinson's Disease Patients With "Wearing-off" Phenomenon
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DRUG: BIA 9-1067|DRUG: Entacapone|DRUG: Placebo|DRUG: Levodopa|DRUG: Carbidopa|DRUG: Benserazide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Open-label, Prospective, Multicenter, Post-market Study to Evaluate the Reverse Medacta Shoulder System of Total Shoulder Prosthesis.
Status: RECRUITING
Conditions: Shoulder Prosthesis
Interventions: DEVICE: Medacta Shoulder System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Masitinib in Severe Indolent or Smoldering Systemic Mastocytosis
Status: COMPLETED
Conditions: Indolent Systemic Mastocytosis
Interventions: DRUG: Masitinib|DRUG: Placebo|OTHER: Best Supportive Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The MOCA I Study - Microvascular Obstruction With CoFI™ System Assessment
Status: RECRUITING
Conditions: STEMI - ST Elevation Myocardial Infarction|Microvascular Obstruction
Interventions: DEVICE: CorFlow Controlled Flow Infusion System - CoFI™
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Metoclopramide Versus Ketorolac for Tension-type Headache
Status: COMPLETED
Conditions: Headache
Interventions: DRUG: Metoclopramide|DRUG: Ketorolac
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Anti-Diabetic Medications to Fight PD and LBD
Status: RECRUITING
Conditions: Lewy Body Dementia|Parkinson Disease
Interventions: DRUG: Sitagliptin|DRUG: Dapagliflozin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Pharmacodynamic Study of SLM0807, HKB0701 and CJ30001 in Healthy Subject
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: DRUG: Period I : HKB0701, Period II : HKB0701 and SLM0807, Period III : CJ30001|DRUG: Period I : HKB0701 and SLM0807, Period II : CJ30001, Period III : HKB0701|DRUG: Period I : CJ30001, Period II : HKB0701, Period III : HKB0701 and SLM0807
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Safety of Frontline Tislelizumab in Patients With de Novo Hodgkin Lymphoma Unsuitable for Standard Frontline Chemotherapy
Status: RECRUITING
Conditions: Hodgkin Lymphoma
Interventions: DRUG: Tislelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Denosumab Compared With Risedronate in Individuals Taking Glucocorticoids
Status: COMPLETED
Conditions: Steroid-induced Osteopor, Glucocorticoid-induced Ostepor
Interventions: DRUG: Denosumab|DRUG: Placebo for risendronate|DRUG: Risendronate|DRUG: Placebo for denosumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Toripalimab in HER2- Metastatic Breast Cancer Patients Treated With Metronomic Vinorelbine
Status: UNKNOWN
Conditions: Metastatic Breast Cancer
Interventions: DRUG: Vinorelbine 40mg|BIOLOGICAL: Toripalimab 240mg|BIOLOGICAL: Bevacizumab 5 mg/kg|DRUG: Cyclophosphamide 50 mg|DRUG: Capecitabine 500Mg Oral Tablet|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Asian Myeloproliferative Neoplasm (MPN) Registry
Status: RECRUITING
Conditions: Myeloproliferative Neoplasm|Polycythemia Vera|Essential Thrombocythemia|Post-polycythemia Vera Myelofibrosis|Post-essential Thrombocythemia Myelofibrosis|Primary Myelofibrosis|Primary Myelofibrosis, Prefibrotic Stage|Primary Myelofibrosis, Fibrotic Stage
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Double Blind Trial of Duloxetine in Chronic Fatigue Syndrome
Status: COMPLETED
Conditions: Fatigue Syndrome, Chronic
Interventions: DRUG: Duloxetine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Efficacy, and Pharmacokinetic Study of Intravenous Ibuprofen in Pediatric Patients
Status: COMPLETED
Conditions: Fever
Interventions: DRUG: ibuprofen|DRUG: acetaminophen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endometrial Safety Study
Status: COMPLETED
Conditions: Postmenopause
Interventions: DRUG: 0.25mg DRSP / 0.5mg E2 (BAY86-4891)|DRUG: 0.5mg NETA / 1.0mg E2 (Activella)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety of VAX102 Vaccine Given With Seasonal Flu Vaccine in Healthy Adults
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: VAX102|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Impact of "No-touch" Technique on the Outcome of Liver Transplantation for Hepatocellular Carcinoma
Status: NOT_YET_RECRUITING
Conditions: Liver Transplantation|No-touch Technique|Hepatocellular Carcinoma
Interventions: PROCEDURE: Liver transplantation with "No-touch" technique
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study to Evaluate the Safety and Efficacy of 13 Weeks of the Selective Androgen Receptor Modulator (SARM) GSK2881078 in Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Cachexia
Interventions: DRUG: GSK2881078|DRUG: Matching Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: High-sensitivity Troponin in Cardiac Surgery
Status: COMPLETED
Conditions: Heart; Dysfunction Postoperative, Cardiac Surgery|Myocardial Infarction|Myocardial Injury
Interventions: OTHER: serum concentration changes cardiac biomarkers
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Electroencephalography (EEG) Predictors of Transcranial Direct Current Stimulation (tDCS) in Obsessive-Compulsive Disorder (OCD)
Status: UNKNOWN
Conditions: Obsessive-Compulsive Disorder
Interventions: DEVICE: High-Definition transcranial direct current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Docetaxel, Trabectedin, and G-CSF or Pegfilgrastim in Treating Patients With Recurrent or Persistent Ovarian Epithelial Cancer, Primary Peritoneal Cavity Cancer, or Fallopian Tube Cancer
Status: COMPLETED
Conditions: Fallopian Tube Cancer|Ovarian Cancer|Primary Peritoneal Cavity Cancer
Interventions: BIOLOGICAL: filgrastim|BIOLOGICAL: pegfilgrastim|DRUG: docetaxel|DRUG: trabectedin
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Of Galcanezumab In Participants With Episodic Cluster Headache
Status: COMPLETED
Conditions: Episodic Cluster Headache
Interventions: DRUG: Galcanezumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II Combination of Temsirolimus and Sorafenib in Advanced Hepatocellular Carcinoma
Status: COMPLETED
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Temsirolimus|DRUG: Sorafenib:
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Zeiss® IOLMaster 700 Corneal Topography Module Comparison With Schwind's Sirius Corneal Topography®
Status: UNKNOWN
Conditions: Cataract
Interventions: OTHER: measurement of axial length and keratometry by sonographers with a topographic module
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of PSB and RIFPB Combination With PSB and ESPB Combination in Cardiac Surgery With Sternotomy
Status: NOT_YET_RECRUITING
Conditions: Post Operative Pain
Interventions: OTHER: Parasternal Block and Recto-İntercostal Fascial Plane Block|OTHER: Parasternal Block and Erector Spinae Plane Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Safety, Tolerability and Efficacy of PfSPZ Vaccine in Healthy Children and Infants 5 Months - 9 Years Living in Kenya
Status: COMPLETED
Conditions: Malaria
Interventions: BIOLOGICAL: PfSPZ Vaccine|OTHER: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of ACUITY™ X4 Quadripolar Coronary Venous Leads and RELIANCE™ 4-FRONT Defibrillation Leads
Status: COMPLETED
Conditions: Cardiac Resynchronization Therapy
Interventions: DEVICE: ACUITY X4 quadripolar coronary venous lead and RELIANCE 4-FRONT defibrillation lead
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High Intensity Laser Therapy in Carpal Tunnel Syndrome
Status: COMPLETED
Conditions: Carpal Tunnel Syndrome|Entrapment Neuropathy|Median Neuropathy|Musculoskeletal Diseases
Interventions: DEVICE: High-intensity laser therapy (HILT)|DEVICE: Sham High-intensity laser therapy (sham HILT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Elbasvir/Grazoprevir (EBR/GZR) and Sofosbuvir (SOF) With and Without Ribavirin (RBV) in Cirrhotic Subjects With Chronic Hepatitis C Virus (HCV) Genotype 3 (GT3) Infection (MK-5172-083)
Status: COMPLETED
Conditions: Hepatitis C
Interventions: DRUG: Grazoprevir|DRUG: Elbasvir|DRUG: Ribavirin|DRUG: Sofosbuvir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immune Response to Vaccinations in Hematopoietic Stem Cell Transplant Recipients
Status: COMPLETED
Conditions: Vaccination|Hematopoietic Stem Cells
Interventions: BIOLOGICAL: immune biomarkers to evaluate vaccine response in HSCT recipients
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Increased Calorie Intake to Reverse Energy Deficiency in Exercising Women: Impact on Bone and Menstrual Cyclicity
Status: COMPLETED
Conditions: Menstrual Irregularity
Interventions: BEHAVIORAL: EAMD+Calories
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of ST266 Versus Saline in Treating Skin Irritation From Radiation
Status: COMPLETED
Conditions: Radiation-induced Dermatitis
Interventions: BIOLOGICAL: ST266
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Stereotactic Body Radiotherapy for Oligo-Progression Metastatic Non-Small Cell Lung Cancer
Status: RECRUITING
Conditions: Metastatic Non-Small Cell Lung Cancer|NSCLC Stage IV|OligoProgressive Metastatic Disease
Interventions: RADIATION: Stereotactic Body Radiotherapy|DRUG: second-line systemic therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Protest Trial: TXA vs Saline
Status: ENROLLING_BY_INVITATION
Conditions: Lung Transplant; Complications
Interventions: DRUG: Tranexamic Acid|OTHER: Saline (placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: 3-part Study to Evaluate Safety, Tolerability, Pharmacokinetics & Pharmacodynamics of Multiple Doses of CC-220 and Relative Bioavailability of a Formulated CC-220 Capsule
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: CC-220|DRUG: CC-220|DRUG: CC-220|DRUG: CC-220|DRUG: Placebo|DRUG: CC-220|DRUG: CC-220|DRUG: CC-220
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Renal Stent Placement for the Treatment of Renal Artery Stenosis in Patients With Resistant Hypertension
Status: COMPLETED
Conditions: Renal Artery Stenosis|Hypertension, Renovascular
Interventions: DEVICE: iCAST™ Rx Stent System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study to Evaluate the Efficacy and Safety of TLC388 in Advanced/Metastatic RCC Patients
Status: COMPLETED
Conditions: Advanced/Metastasis Renal Cell Carcinoma
Interventions: DRUG: Lipotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Soticlestat in Adults and Children With Rare Epilepsies
Status: ACTIVE_NOT_RECRUITING
Conditions: Epilepsy|Dravet Syndrome (DS)|Lennox-Gastaut Syndrome (LGS)
Interventions: DRUG: Soticlestat
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pembrolizumab in Neoplasms or Lymphomas
Status: SUSPENDED
Conditions: Lymphoma|Histiocytic Sarcoma|Follicular Dendritic Cell Sarcoma|Interdigitating Dendritic Cell Sarcoma
Interventions: DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diagnostic Accuracy of a Panel of Bacterial Gene Markers (M3) for Colorectal Advanced Neoplasia
Status: RECRUITING
Conditions: Colorectal Cancer|Colorectal Neoplasms|Colorectal Adenoma
Interventions: DIAGNOSTIC_TEST: Fecal immunochemical test (FIT)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparing Efficacy Preoperative Nebulized: Ketamine , Mgspo4 ,and Lidocaine In Attenuating Endotracheal Sore Throat
Status: COMPLETED
Conditions: Sore Throat
Interventions: DRUG: Ketamine|DRUG: Magnesium Sulfate|DRUG: Lidocaine|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Zoledronate in Preventing Osteoporosis in Patients With Primary Malignant Glioma
Status: COMPLETED
Conditions: Brain Tumors|Osteoporosis|Central Nervous System(CNS)Malignancies
Interventions: DRUG: IV Zometa
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Potassium Oxalate and Placebo and Post-bleaching Sensitivity
Status: COMPLETED
Conditions: Medicaments Substances in Therapeutic Use
Interventions: PROCEDURE: Potassium oxalate 5% gel|PROCEDURE: Placebo gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized, Double-Blind, Placebo-Controlled, Phase 2 Study In Subjects With Osteoarthritic Pain Of The Knee
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: DRUG: PF-04136309|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Telerehabilitation Exercise for Bening Paroxysmal Positional Vertigo
Status: COMPLETED
Conditions: Benign Paroxysmal Vertigo
Interventions: OTHER: Telerehabilitation group (n=21)|OTHER: Control Group (n=21)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Prospective Multicenter Study for Early Evaluation of Acute Chest Pain
Status: UNKNOWN
Conditions: Chest Pain|Acute Aortic Dissection|Pulmonary Embolism|Acute Myocardial Infarction Type 1|Acute Coronary Syndrome
Interventions: DIAGNOSTIC_TEST: Coronary angiography|DIAGNOSTIC_TEST: CT angiography of aorta|DIAGNOSTIC_TEST: CT angiography of pulmonary arteries.|DIAGNOSTIC_TEST: Electrocardiogram|DIAGNOSTIC_TEST: Cardiac Troponin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety, Tolerability, Pharmacokinetic, and Efficacy Study of AZD5213 in Adolescents With Tourette's Disorder
Status: COMPLETED
Conditions: Tourette Syndrome
Interventions: DRUG: AZD5213 and placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Carotenoid and Flavonoid Absorption From Red and Tangerine-Type Tomatoes
Status: ACTIVE_NOT_RECRUITING
Conditions: Carotenoid and Flavonoid Absorption
Interventions: OTHER: Tangerine tomato juice|OTHER: Red tomato juice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: FOLFOX With Bevacizumab in Metastatic or Unresectable Gastroesophageal and Gastric Cancer
Status: COMPLETED
Conditions: Gastroesophageal Cancer|Gastric Cancer
Interventions: DRUG: FOLFOX|DRUG: bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Risk-Oriented Therapeutic Strategy for Adult Acute Myelogenous Leukemia
Status: COMPLETED
Conditions: Acute Myelogenous Leukemia
Interventions: BEHAVIORAL: Two-step remission induction and risk-oriented consolidation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bacteremia in Periodontal Patients
Status: COMPLETED
Conditions: Gingivitis|Periodontitis
Interventions: DRUG: Chlorhexidine gluconate mouth rinse|PROCEDURE: Periodontal instrumentation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION