pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Motivational Interviewing to Increase Physical Activity to Treat Depression in People Aging With MS or SCI
Status: COMPLETED
Conditions: Multiple Sclerosis|Spinal Cord Injury
Interventions: BEHAVIORAL: Motivational interviewing|BEHAVIORAL: Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of the Fixed Dose Combination of Glimepiride+Metformin in Type 2 Diabetic Patients Inadequately Controlled
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Glimepiride+metformin (Amaryl M®) - HOE4900
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Veliparib and Radiation Therapy in Treating Patients With Advanced Solid Malignancies With Peritoneal Carcinomatosis, Epithelial Ovarian, Fallopian, or Primary Peritoneal Cancer
Status: COMPLETED
Conditions: Adult Solid Neoplasm|Peritoneal Carcinomatosis|Recurrent Fallopian Tube Carcinoma|Recurrent Ovarian Carcinoma|Recurrent Primary Peritoneal Carcinoma
Interventions: OTHER: Laboratory Biomarker Analysis|OTHER: Quality-of-Life Assessment|RADIATION: Radiation Therapy|DRUG: Veliparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevention of Anthracycline-Induced Cardiac Dysfunction With Dexrazoxane in Patients With Diffuse Large-B Cell Lymphoma
Status: RECRUITING
Conditions: DLBCL - Diffuse Large B Cell Lymphoma
Interventions: DRUG: Dexrazoxane|DRUG: Rituximab|DRUG: Cyclophosphamide|DRUG: Doxorubicin|DRUG: Vincristine|DRUG: Prednisolone|DRUG: Lenalidomide|DRUG: Pegfilgrastim
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: LMA Protector Cuff Pilot vs LMA Supreme Among Anaesthetised, Non-Paralysed Patients
Status: COMPLETED
Conditions: Anesthesia
Interventions: DEVICE: LMA Protector Cuff Pilot|DEVICE: LMA Supreme
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Elderly Cancer PatIents, Safety and qualiTy of Life Under immunOtheraPies
Status: UNKNOWN
Conditions: Advanced or Metastatic Melanoma|Advanced or Metastatic NSCLC
Interventions: DRUG: immune-checkpoint inhibitors therapies
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radiation-associated Carotid Artery Disease in Patients With Nasopharyngeal Carcinoma
Status: UNKNOWN
Conditions: Nasopharyngeal Carcinoma|Carotid Artery Diseases
Interventions: DIAGNOSTIC_TEST: Measurement of intima media thickness of carotid artery|DIAGNOSTIC_TEST: Detection and measurement of carotid plaques|DIAGNOSTIC_TEST: Carotid Color Flow Duplex Testing|DIAGNOSTIC_TEST: Montreal Cognitive Assessment|OTHER: Medical history of cardiovascular risk factors and cardiovascular diseases
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phase II Doubleblind Exploratory Study of GSK2402968 in Ambulant Subjects With Duchenne Muscular Dystrophy
Status: COMPLETED
Conditions: Muscular Dystrophies
Interventions: DRUG: GSK2402968|DRUG: matched placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Treatment With Balaglitazone in Type 2 Diabetes Patients on Stable Insulin Therapy
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Balaglitazone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Tele-based Resisted Exercise for COPD
Status: COMPLETED
Conditions: COPD|Pulmonary Rehabilitation|Telerehabilitation|Cardiopulmonary Exercise Test|Compliance, Patient
Interventions: OTHER: Education|OTHER: Video-based pulmonary rehabilitation|OTHER: Booklet-based pulmonary rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Correlation Between Muscle Thickness and Inflammation With Ventilator Use in Critically Ill Patients
Status: COMPLETED
Conditions: Ventilation Therapy; Complications
Interventions: OTHER: Diaphragm thickness|OTHER: Cross-sectional area of rectus femoris muscle|OTHER: Cross-sectional area of biceps brachii|DIAGNOSTIC_TEST: C-Reactive Protein (CRP) Level
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Efficacy of the CarboFix Pedicle Screw System
Status: COMPLETED
Conditions: Degenerative Disc Disease|Spondylolisthesis|Spinal Stenosis|Spinal Curvatures|Tumor
Interventions: DEVICE: Pedicle screw system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Proximal Colon Retroflexion in Colorectal Cancer Screening Programme
Status: COMPLETED
Conditions: Colorectal Neoplasms|Adenoma Detection Rate
Interventions: PROCEDURE: Proximal retroflexion|PROCEDURE: Frontal view
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SCREENING
Clinical trial: The Effects of Different Interior Decorations in a Psychiatric Intensive Care Unit.
Status: COMPLETED
Conditions: Mental Disorders
Interventions: PROCEDURE: Psychiatric intensive care unit in Norwegian home style|PROCEDURE: Psychiatric intensive care unit sparsely furnished and not decorated
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Double Blind Crossover Study on the Effect of Methylphenidate on Decision-making Ability of Adults With ADHD Compared to Healthy Adults
Status: UNKNOWN
Conditions: ADHD
Interventions: DRUG: methylphenidate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Cisatracurium on Sccinylcholine-induced Fasciculations
Status: COMPLETED
Conditions: Fasciculations
Interventions: DRUG: Cisatracurium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Adolescent Acts of Kindness Intervention With Reflection
Status: RECRUITING
Conditions: Mental Health Wellness 1
Interventions: BEHAVIORAL: Other-Focused Acts of Kindness Intervention with Reflection|BEHAVIORAL: Other-Focused Acts of Kindness Intervention|BEHAVIORAL: Daily Reports
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pharmacokinetic (PK) and Pharmacodynamic (PD) Modeling of Ampicillin and Gentamicin in Peripartum Patients
Status: COMPLETED
Conditions: Drug Metabolism During Pregnancy
Interventions: DRUG: Ampicillin|DRUG: Ampicillin and Gentamicin|DRUG: Gentamicin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Thoracic Vibration With Classical Respiratory Physiotherapy in Patients With Mechanical Ventilation
Status: UNKNOWN
Conditions: Pulmonary Medicine|Ventilators, Mechanical
Interventions: PROCEDURE: classical respiratory physiotherapy with thoracic vibration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Milk Polar Lipids Consumption, Lipid Metabolism, and Inflammation in Menopausal Women
Status: COMPLETED
Conditions: Cardiometabolic Risk
Interventions: OTHER: 3g milk polar lipid fortified cheese consumption|OTHER: 5g milk polar lipid fortified cheese consumption|OTHER: Unfortified cheese product consumption
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Bortezomib, Rituximab, Cyclophosphamide, and Prednisone in Treating Patients With Relapsed or Refractory Indolent Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Leukemia|Lymphoma
Interventions: BIOLOGICAL: rituximab|DRUG: bortezomib|DRUG: cyclophosphamide|DRUG: prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Bifidobacterium Longum OLP-01 Supplement on Cognitive Function, Exercise Performance, Nutritional Status and Gut Microbiota in Stroke Patients
Status: UNKNOWN
Conditions: Stroke
Interventions: DIETARY_SUPPLEMENT: Bifidobacterium longum OLP-01|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Dynamic Quadriceps Muscle Stimulation for Treatment of Patellofemoral Pain
Status: COMPLETED
Conditions: Patellofemoral Pain Syndrome|Anterior Knee Pain Syndrome
Interventions: DEVICE: KneeStim mobile rehabilitation assistance device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: IMPACT-CABG Trial: IMPlantation of Autologous CD133+ sTem Cells in Patients Undergoing Coronary Artery Bypass Grafting
Status: COMPLETED
Conditions: Heart Failure|Heart Attack|Coronary Artery Bypass Surgery
Interventions: BIOLOGICAL: Injection of autologous CD133+ stem cells at the time of coronary artery bypass grafting|BIOLOGICAL: Injection of autologous CD133+ stem cells at the time of coronary artery bypass grafting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transcutaneous Electrical Nerve Stimulation for Pain Control During First-trimester Abortion
Status: COMPLETED
Conditions: Abortion in First Trimester|Pain
Interventions: DEVICE: Transcutaneous electrical nerve stimulation (TENS)|DEVICE: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Frequency of Trigeminocardiac Reflex During the Extraction of Impacted Mandibular Wisdom Teeth
Status: COMPLETED
Conditions: Trigemino-Cardiac Reflex|Impacted Third Molar Tooth
Interventions: PROCEDURE: Monitoring and Surgical removal of mandibular impacted wisdom teeth, using Gow-Gates anesthesia technique|PROCEDURE: Monitoring and Surgical removal of mandibular impacted wisdom teeth, using inferior alveolar nerve block anesthesia technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SCREENING
Clinical trial: Does Screening With the Galleri Test in the NHS Reduce the Likelihood of a Late-stage Cancer Diagnosis in an Asymptomatic Population? A Randomised Clinical Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Cancer
Interventions: DEVICE: Multi-cancer early detection test (Galleri test)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Safety Study of SCIO-469 to Treat Patients With Active Rheumatoid Arthritis Receiving Methotrexate
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: SCIO-469
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Combined Single and Multiple Ascending Dose Study of ASP6858 in Healthy Subjects
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: ASP6858|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Investigation of Cycloserine as a Smoking Cessation Treatment
Status: COMPLETED
Conditions: Nicotine Addiction
Interventions: DRUG: Cycloserine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Stabilization Exercises With and Without Connective Tissue Massage for Chronic Mechanical Neck Pain
Status: UNKNOWN
Conditions: Neck Pain Musculoskeletal
Interventions: BEHAVIORAL: "Exercise" and "connective tissue massage"|BEHAVIORAL: "Exercise"
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pain Control After Aortic EndoaneurYsmEctomy (POPEYE)
Status: RECRUITING
Conditions: Postoperative Pain|Abdominal Aortic Aneurysm
Interventions: PROCEDURE: Postoperative pain control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Real-Time Support for Exercise Persistence in COPD
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive|COPD|Emphysema|Chronic Bronchitis
Interventions: BEHAVIORAL: Coached exercise persistence intervention|BEHAVIORAL: Self-Monitored exercise persistence intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Field Evaluations of Innovative Tools for Vector-borne Disease Control in Conflict-affected Communities
Status: COMPLETED
Conditions: Malaria|Childhood ALL|Vector Borne Diseases
Interventions: COMBINATION_PRODUCT: Mesh - spatial repellent impregnated with transfluthrin (2500mg)|BEHAVIORAL: Information and Education Campaigns (IEC)|DIAGNOSTIC_TEST: test and treat malaria cases
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effects of Homemade Oral Nutrition Supplements for Patients on Hemodialysis With Protein-energy Wasting
Status: NOT_YET_RECRUITING
Conditions: Protein-Energy Wasting|Kidney Failure|Hemodialysis
Interventions: OTHER: Homemade oral nutrition supplements|OTHER: Commercial oral nutrition supplements
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stereotactic Ablative Radiotherapy (SABR) for Low Risk Prostate Cancer With Injectable Rectal Spacer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DEVICE: Injectable Rectal Spacer (SpaceOAR, Duraseal or equivalent)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare the Efficacy of QAV680 Against Placebo in Treating Seasonal Allergic Rhinitis in an Environmental Exposure Chamber
Status: COMPLETED
Conditions: Seasonal Allergic Rhinitis
Interventions: DRUG: QAV680|DRUG: QAV680|DRUG: Mometasone Furoate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Arthrometry and Clinical Tests for Diagnosing ACL Tears
Status: RECRUITING
Conditions: Anterior Cruciate Ligament Injuries|Anterior Cruciate Ligament Rupture|Anterior Cruciate Ligament Tear
Interventions: DIAGNOSTIC_TEST: Athrometer
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Performance of the Travoprost Intraocular Implant
Status: COMPLETED
Conditions: Glaucoma, Open-Angle|Ocular Hypertension
Interventions: DRUG: Travoprost Intracameral Implant exchanged at Month 12|DRUG: Travoprost Intracameral Implant exchanged at Month 3|DRUG: Travoprost Intracameral Implant exchanged at Month 6|DRUG: Travoprost Intracameral Implant exchanged at Month 24|DRUG: Travoprost intracameral implant exchanged at Month 21|DRUG: Travoprost intracameral implant exchanged at Month 18|DRUG: Travoprost intracameral implant exchanged at Month 15
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Postoperative Dose of Parathyroid Hormone as a Marker for the Occurrence of Hypoparathyroidism After Total Thyroidectomy
Status: COMPLETED
Conditions: Hypoparathyroidism
Interventions: BIOLOGICAL: immediate post operative bioassay of Parathyroid Hormone
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Platelet Rich Plasma in Carpal Tunnel Syndrome
Status: UNKNOWN
Conditions: Carpal Tunnel Syndrome
Interventions: DRUG: Local platelet rich plasma (PRP) injection-T-Lab PRP kit|DRUG: Local steroid injection-Diprospan ®, Schering Plough
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Reduced Frequency Physical Therapy in Total Knee Arthroplasty
Status: COMPLETED
Conditions: Knee Osteoarthritis|Knee Arthritis|Knee Arthropathy
Interventions: OTHER: Physical Therapy|OTHER: In-home Exercise Equipment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Switching From a Regimen of Two Nucleos(t)Ide Reverse Transcriptase Inhibitors (NRTI) Plus a Third Agent to a Fixed Dose Combination (FDC) of Bictegravir/Emtricitabine/Tenofovir Alafenamide (B/F/TAF), in Virologically-Suppressed, HIV-1 Infected African American Participants
Status: COMPLETED
Conditions: HIV-1 Infection
Interventions: DRUG: B/F/TAF|DRUG: NRTIs|DRUG: Third Agent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial of Sugemalimab and Chemotherapy in Unresectable Stage III NSCLC
Status: RECRUITING
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: Sugemalimab and Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Tamsulosin 0.4 mg Sustained Release Film-coated Tablets
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Tamsulosin 0.4 mg Sustained Release Tablet (produced by PT Dexa Medica, Indonesia)|DRUG: Harnal® OCAS 0.4 mg Prolonged Release Tablet (produced by Astellas Pharma Europe B.V., The Netherlands, imported by PT Combiphar, Indonesia)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Videolaryngoscope Versus Fiberoptic Bronchoscope for the Awake Intubation
Status: UNKNOWN
Conditions: Need of Awake Intubation for Difficult Airways
Interventions: DEVICE: Videolaryngoscope|DEVICE: Fiberoptic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: FOLFOX-A For Locally Advanced Pancreatic Cancer: A Phase II Brown University Oncology Research Group Trial
Status: COMPLETED
Conditions: Locally Advanced Pancreatic Cancer|Pancreatic Cancer
Interventions: DRUG: FOLFOXA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Eye Patch Therapy for Central Serous Retinopathy (CSR)
Status: COMPLETED
Conditions: Central Serous Retinopathy (CSR)
Interventions: DEVICE: Eye Patching
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Epigenetic Modulation in Relapsed/Refractory Diffuse Large B-Cell Lymphoma (DLBCL)
Status: TERMINATED
Conditions: Diffuse Large B-cell Lymphoma
Interventions: DRUG: RAD001|DRUG: LBH589|DRUG: Doublet (RAD001 and LBH589)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testing the Leadership and Organizational Change for Implementation (LOCI) Intervention
Status: COMPLETED
Conditions: Substance Use Disorder|Mental Health Disorder
Interventions: BEHAVIORAL: LOCI|BEHAVIORAL: Internet Based Webinar Leadership Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Pharmacogenetic Trial of Doxazosin for Treatment of Cocaine Abuse
Status: COMPLETED
Conditions: Cocaine Dependence
Interventions: DRUG: Doxazosin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Montelukast Versus Co Enzyme in Sepsis
Status: COMPLETED
Conditions: Sepsis
Interventions: DRUG: Montelukast Sodium 10 mg|DRUG: Co-Enzyme Q10|DRUG: Standard Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Acyclovir to Help Prevent HIV Infection in People With Genital Herpes
Status: COMPLETED
Conditions: HIV Infections|HIV Seronegativity|Herpes Genitalis
Interventions: DRUG: Acyclovir|DRUG: Acyclovir placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Effects of Moringa Oleifera Leaves on Glycemia, Lipemia and Inflammatory Profile in Prediabetic Patients
Status: COMPLETED
Conditions: PreDiabetes
Interventions: DIETARY_SUPPLEMENT: Moringa|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of Comfilcon A Toric Contact Lenses and Samfilcon A Toric Contact Lenses
Status: COMPLETED
Conditions: Astigmatism
Interventions: DEVICE: comfilcon A toric lens|DEVICE: samfilcon A toric lens
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Anderson Circulating Tumor Cell Burden (CTCB) Study
Status: TERMINATED
Conditions: Cancer|Spinal Disease|Vertebral Compression Fractures
Interventions: PROCEDURE: Kyphoplasty|PROCEDURE: Vertebroplasty|DEVICE: Cavity SpineWand
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Home-based Transcranial Direct Current Stimulation (tDCS) for Treatment of Attention-deficit/Hyperactivity Disorder (ADHD)
Status: RECRUITING
Conditions: Attention Deficit Disorder|Attention Deficit Disorder With Hyperactivity
Interventions: DEVICE: 2 mA transcranial direct current stimulation (tDCS)|DEVICE: 1 mA transcranial direct current stimulation (tDCS)|DEVICE: Sham transcranial direct current stimulation (tDCS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Melissa Extract on Sleep Characteristics
Status: NOT_YET_RECRUITING
Conditions: Sleep Disorder|Anxiety|Quality of Life
Interventions: DIETARY_SUPPLEMENT: Melissa phytosome|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Multimodal Strategy for Early Diagnosis of Men at High Genetic Risk of Prostate Cancer (HRPCa-II)
Status: NOT_YET_RECRUITING
Conditions: Prostate Cancer
Interventions: PROCEDURE: Multiparameric MRI with injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Sodium Lowering Vascular Effects Trial
Status: RECRUITING
Conditions: Endothelial Dysfunction|Vascular Stiffness|Left Ventricular Hypertrophy|Left Ventricular Dysfunction
Interventions: BEHAVIORAL: Sodium Reduction Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Stereotactic Radiotherapy (SBRT) in Patients With Locally Advanced Pancreatic Cancer (LAPC)
Status: COMPLETED
Conditions: Locally Advanced Pancreatic Cancer
Interventions: RADIATION: Stereotactic Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Ropivacaine and Bupivacaine in DTFNB Anesthesia in Patients Undergoing Phacoemulsification
Status: COMPLETED
Conditions: Cataract Unilateral Pending Extraction|Anesthesia
Interventions: PROCEDURE: Deep Topical Fornix Nerve block anesthesia|DRUG: Ropivacaine|DRUG: Bupivacaine|DRUG: Proparacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of Ticagrelor vs. Prasugrel on Inflammation, Arterial Stiffness, Endothelial Function, and Circulating Endothelial Progenitor Cells in Diabetic Patients With Non-ST Elevation Acute Coronary Syndrome (NSTE-ACS) Requiring Coronary Stenting
Status: COMPLETED
Conditions: Acute Coronary Syndrome
Interventions: DRUG: Ticagrelor|DRUG: Prasugrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: AImmune - Artificial Intelligence Algorithm for Identification of Immunogenic Neoepitopes of Cancer to Predict and Boost Patient's Response to Immunotherapies.
Status: UNKNOWN
Conditions: Non Small Cell Lung Cancer|Neoepitopes|Neoantigens|Immunotherapy|Next Generation Sequencing (NGS)|Personalized Neoantigen Cancer Vaccine
Interventions: BIOLOGICAL: Collection of biopsy (FFPE), blood (PBMC) and stool
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Evaluate the Pharmacokinetics in Participants After Dosing With Pegilodecakin (LY3500518)
Status: COMPLETED
Conditions: Healthy Adult Subjects
Interventions: BIOLOGICAL: Pegilodecakin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Improving Care of Osteoporosis: Multi-Modal Intervention to Increase Testing and Treatment (ICOMMIITT)
Status: COMPLETED
Conditions: Osteoporosis
Interventions: BEHAVIORAL: Patient educational DVD and brochure|BEHAVIORAL: Physician web modules|BEHAVIORAL: System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Unrefined Salmon Oil as Dietary Supplement in Adult Asthmatics
Status: ACTIVE_NOT_RECRUITING
Conditions: Asthma
Interventions: DIETARY_SUPPLEMENT: CARDIO®|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Phase 1 Trial of ERX-315 in Participants With Advanced Solid Tumors
Status: NOT_YET_RECRUITING
Conditions: Advanced Solid Tumor|Metastatic Breast Cancer|Metastatic Ovarian Cancer|Metastatic Endometrial Cancer|Metastatic Liver Cancer|Metastatic Pancreatic Cancer
Interventions: DRUG: ERX-315
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Quilting Sutures After Mastectomy
Status: NOT_YET_RECRUITING
Conditions: Breast Cancer
Interventions: PROCEDURE: Mastectomy with Quilting sutures without drain placement|PROCEDURE: Mastectomy with Conventional sutures with drain placement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Contribution of a Non Medicamentous Approach by Hypnosis on Quality of Life in Crohn Disease
Status: UNKNOWN
Conditions: Crohn Disease
Interventions: DRUG: immunosuppressor/TNFalpha|BEHAVIORAL: Hypnosis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy and Safety of IVM/ALB Co-administration
Status: COMPLETED
Conditions: Trichuriasis
Interventions: DRUG: Albendazole|DRUG: Albendazole and Ivermectin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Feasibility Study of Autologous Stromal Vascular Fraction (SVF) Cells for Treatment of Osteoarthritis
Status: WITHDRAWN
Conditions: Osteoarthritis
Interventions: BIOLOGICAL: Autologous adipose tissue stromal vascular fraction
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Compare the Effect of Different Nutritional Pathways on Improving Nutritional Status of Esophageal Cancer Patients Undergoing Chemoradiotherapy
Status: COMPLETED
Conditions: Esophageal Squamous Cell Carcinoma|Chemoradiotherapy|Enteral Nutrition
Interventions: DIETARY_SUPPLEMENT: Dietary guidance
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effectiveness and Safety of the Colonoscopy With "Visualization" Balloon
Status: COMPLETED
Conditions: Colonic Adenomatous Polyps
Interventions: DEVICE: Visualization balloon|DEVICE: Traditional CO2 insufflation colonoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Complex-Posttraumatic Stress Disorder in Urban Egypt: Pilot Testing of a Culturally-adapted Evidence-Based Treatment Manual and Development of a Culture-specific Diagnostic
Status: RECRUITING
Conditions: Complex Post-Traumatic Stress Disorder
Interventions: BEHAVIORAL: Enhanced Skills Training in Affective and Interpersonal Regulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PolyPEPI1018 Vaccine and CDx for the Treatment of Metastatic Colorectal Cancer (OBERTO)
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: BIOLOGICAL: PolyPEPI1018 CRC Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of the DALI LDL-adsorber and MONET Lipoprotein Filter
Status: COMPLETED
Conditions: Hypercholesterolemia, Familial|LIPOPROTEIN TYPES--Lp SYSTEM Lp(a) HYPERLIPOPROTEINEMIA
Interventions: DEVICE: DALI-adsorber|DEVICE: MONET-Lipoprotein filter
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study to Assess the Pharmacokinetics of GSK1278863A Coadministered With a High Fat Meal or an Inhibitor of CYP2C8 (Gemfibrozil)
Status: COMPLETED
Conditions: Anaemia
Interventions: DRUG: GSK1278863|DRUG: GSK1278863 + food|DRUG: Gemfibrozil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effects of Docosahexaenoic Acid (DHA)-Rich Fish Oil on Cerebral Haemodynamics
Status: COMPLETED
Conditions: Cerebral Blood Flow|Cognitive Function
Interventions: DIETARY_SUPPLEMENT: DHA-rich fish oil|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Utilization of Platelet Gel for Treatment of Diabetic Foot Ulcers
Status: COMPLETED
Conditions: Diabetic Foot Ulcers
Interventions: BIOLOGICAL: Platelet Gel|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: CARDIA-Salt Sensitivity of Blood Pressure (SSBP)
Status: ACTIVE_NOT_RECRUITING
Conditions: Salt Sensitivity of Blood Pressure|Hypertension
Interventions: DIETARY_SUPPLEMENT: High Salt Diet|DIETARY_SUPPLEMENT: Low Salt Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study of the Safety and Effectiveness of Simeprevir and Sofosbuvir for Patients With HIV and Hepatitis C
Status: WITHDRAWN
Conditions: Hepatitis C, Chronic|HIV CDC Category A1
Interventions: DRUG: Sofosbuvir + Simeprevir
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of CPP-ACP With/Without Fl on White Spot Lesion,Salivary pH and fl Release in High Caries Risk Patients
Status: UNKNOWN
Conditions: Caries
Interventions: DRUG: CPP-ACP paste
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Footwear and Exercise for Knee Osteoarthritis (FiREwORK Trial)
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: DEVICE: Flat Flexible Shoes|DEVICE: Stable Supportive Shoes|OTHER: Exercise Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Research Study Comparing a New Medicine Oral Semaglutide to Sitagliptin in People With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Oral semaglutide|DRUG: Sitagliptin|DRUG: Placebo (oral semaglutide)|DRUG: Placebo (sitagliptin)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transcranial Low Intensity Focused Ultrasound Neuromodulation as a Probe to Study Human Emotion and Cognitive Function
Status: NOT_YET_RECRUITING
Conditions: Depressive Disorder, Major
Interventions: DEVICE: LIFUP sonication to the amygdala
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Sleep Healthy Using The Internet for Older Adult Sufferers of Insomnia and Sleeplessness
Status: COMPLETED
Conditions: Insomnia|Sleep Initiation and Maintenance Disorders
Interventions: BEHAVIORAL: SHUTi (Sleep Health Using the Internet)|BEHAVIORAL: Patient Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Brentuximab Vedotin and Lenalidomide in Treating Patients With Stage IB-IVB Relapsed or Refractory T-Cell Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Lymphomatoid Papulosis|Primary Cutaneous Anaplastic Large Cell Lymphoma|Recurrent Primary Cutaneous T-Cell Non-Hodgkin Lymphoma|Recurrent T-Cell Non-Hodgkin Lymphoma|Refractory Primary Cutaneous T-Cell Non-Hodgkin Lymphoma|Stage I Cutaneous T-Cell Non-Hodgkin Lymphoma|Stage II Cutaneous T-Cell Non-Hodgkin Lymphoma|Stage III Cutaneous T-Cell Non-Hodgkin Lymphoma|Stage IV Cutaneous T-Cell Non-Hodgkin Lymphoma
Interventions: DRUG: Brentuximab Vedotin|OTHER: Laboratory Biomarker Analysis|DRUG: Lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CPAP in SAHS Patients With Hypertension
Status: COMPLETED
Conditions: Sleep Apnea Syndromes|Hypertension
Interventions: DEVICE: CPAP nasal|DEVICE: sham CPAP nasal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating MED2005 & Nitrostat Bioavailability
Status: COMPLETED
Conditions: Erectile Dysfunction
Interventions: DRUG: MED2005|DRUG: Nitrostat 0.6Mg Sublingual Tablet|DRUG: Nitro Pohl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation of Topic Anaesthesia for Laryngoscopy With Fibroscopy During Paediatric Ear Nose Throat (ENT)Consultation
Status: TERMINATED
Conditions: Nasofibroscopy
Interventions: DRUG: Indirect laryngoscopy in the flexible nasofibroscope|DRUG: Indirect laryngoscopy in the flexible nasofibroscope
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Salpingectomy During Conservative Hysterectomy
Status: COMPLETED
Conditions: Genital Diseases, Female|Hysterotomy; Affecting Fetus|Leiomyomata Uteri|Adenomyosis, Endometriosis|Dysfunctional Uterine Bleeding|Cervical Dysplasia|Uterine Prolapse
Interventions: PROCEDURE: conservative hysterectomy I|PROCEDURE: Conservative hysterectomy II
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Metformin Effect on Brain Function in Insulin Resistant Elderly People
Status: COMPLETED
Conditions: Insulin Resistance|Obesity|Obesity, Abdominal
Interventions: DRUG: Metformin Hydrochloride|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Melanoma Surveillance Photography (MSP) to Improve Early Detection of Melanoma in Ultra-high and High Risk Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Melanoma|Skin Cancer|Anxiety and Fear
Interventions: DEVICE: 2D or 3D Melanoma Surveillance Photography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Computed Tomography Versus Standard 2D Mammography Versus 3D Tomosynthesis
Status: COMPLETED
Conditions: Breast Cancer
Interventions: RADIATION: Tomosynthesis Breast Scanning|RADIATION: Breast CT Scanning
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Dynamic Elastic Garment (DEG) in Patients With Rotator Cuff Tendinopathy
Status: WITHDRAWN
Conditions: Rotator Cuff Tendinopathy
Interventions: DEVICE: Dynamic Elastic Garment (DEG) brace|DRUG: Corticosteroid injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Resilience and Mental Health of Abused Psychiatric Nurses: An Intervention With Biofeedback Training
Status: COMPLETED
Conditions: Psychiatric Nurses, Workplace Violence, Biofeedback Training, and Resilience
Interventions: BIOLOGICAL: bio-feedback training
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: High Intensity Exercise for Increasing Fitness in Patients With Hypertrophic Cardiomyopathy
Status: COMPLETED
Conditions: Hypertrophic Cardiomyopathy
Interventions: BEHAVIORAL: High intensity exercise|BEHAVIORAL: Moderate intensity exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Family Psychoeducation for Adults With Psychotic Disorders in Tanzania
Status: COMPLETED
Conditions: Schizophrenia Spectrum and Other Psychotic Disorders|Mental Disorders, Severe
Interventions: BEHAVIORAL: KUPAA Intervention Group (Culturally Tailored Family Psychoeducation)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Extension in AS: Sustainability of Benefits, Safety and Tolerability
Status: COMPLETED
Conditions: Spondylitis, Ankylosing
Interventions: BIOLOGICAL: Secukinumab|OTHER: Placebo (Pbo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Alemtuzumab and Cyclosporine for the Prevention of Graft vs Host Disease After Stem Cell Transplants
Status: COMPLETED
Conditions: Graft Versus Host Disease|Bone Marrow Transplantation
Interventions: DRUG: Alemtuzumab|DRUG: mycophenolate or cyclosporine and methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Decolonization Rate and Acceptance of a Complete Nasal Decolonization Kit With Povidone Iodine for MRSA Patients
Status: NOT_YET_RECRUITING
Conditions: MRSA
Interventions: DRUG: Betadine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Kidney Damage in Patients Receiving Cisplatin and Ifosfamide for Solid Tumors
Status: SUSPENDED
Conditions: Chemotherapeutic Agent Toxicity|Renal Toxicity|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: cisplatin|DRUG: ifosfamide|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: A Collaborative Public/Private Employment Training and Placement Model ASD Transition Age Youth With Autism Spectrum Disorder (ASD)
Status: COMPLETED
Conditions: Autism Spectrum Disorder
Interventions: BEHAVIORAL: Project SEARCH plus ASD Supports
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sitagliptin Mechanism of Action Study in Patients With Type 2 Diabetes Mellitus (0431-059)
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus (T2DM)
Interventions: DRUG: Comparator: sitagliptin phosphate|DRUG: Comparator: placebo (unspecified)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Finding the Optimal Resistance Training Intensity For Your Bones
Status: RECRUITING
Conditions: Osteoporosis|Osteopenia
Interventions: OTHER: Supervised strength training (group 1)|OTHER: Supervised strength training (group 2)|OTHER: Home exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of the Addition of the Kinesio Taping Method to Conventional Physical Therapy Treatment in Patients With Chronic Nonspecific Low Back Pain
Status: COMPLETED
Conditions: Nonspecific Chronic Low Back Pain
Interventions: OTHER: Conventional Physical Therapy|DEVICE: Kinesio Tex Gold ( Kinesiotaping )
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Burosumab on the Inflammatory Profile of Patients With X-linked Hypophosphatemic Rickets FLAM-XLH
Status: NOT_YET_RECRUITING
Conditions: X-Linked Hypophosphatemic Rickets
Interventions: OTHER: Expression of inflammatory markers (Il6, Il8, Il1β, CXCL1, CCL2, CXCR3, Il1R, Il6R)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Preoperative Epirubicin Paclitaxel Aranesp Study (PREPARE)
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Epirubicin, paclitaxel, cyclophosphamide, Methotrexate, 5 FU, darbepoetin alfa|DRUG: Epirubicin, Cyclophosphamide, Paclitaxel, dabepoetin alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Controlled Trial of Plantain Powder in Infantile Diarrhea
Status: TERMINATED
Conditions: Diarrhea, Infantile
Interventions: DIETARY_SUPPLEMENT: Green banana powder|OTHER: Microcrystalline cellulose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Supermarket Science: Multipronged Approaches to Increasing Fresh, Frozen and Canned Fruit and Vegetable Purchases
Status: COMPLETED
Conditions: Pediatric Obesity
Interventions: BEHAVIORAL: F&V economic incentive|BEHAVIORAL: Cooking Matters Store Tour
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Phase I/II Randomized Study of NBTXR3 Activated by Abscopal or RadScopal Radiation in Combination With Immunotherapy (Anti-PD-1/L-1) for Patients With Advanced Solid Malignancies
Status: RECRUITING
Conditions: Advanced Malignant Solid Neoplasm|Metastatic Malignant Neoplasm in the Liver|Metastatic Malignant Neoplasm in the Lung|Metastatic Malignant Solid Neoplasm
Interventions: OTHER: Hafnium Oxide-containing Nanoparticles NBTXR3|RADIATION: Radiation Therapy|RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comfort Check of CO2 Monitoring Cannulas With Oxygen Delivery
Status: COMPLETED
Conditions: Wearing Comfort
Interventions: DEVICE: Oridion Smart CapnoLine® H Plus with Wedge cannula|DEVICE: Oridion Smart CapnoLine® Plus with Non-Wedge cannula|DEVICE: Experimental sample line Model 3|DEVICE: Experimental sample line Model 4|DEVICE: Experimental sample line Model 5|DEVICE: O2/CO2 cannula w/female luer (Westmed comfort plus #0504)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Postoperative Analgesia of Quadratus Lumborum Block Versus Epidural Block After Major Abdominal Surgeries
Status: COMPLETED
Conditions: Elective Major Abdominal Surgery
Interventions: OTHER: Thoracic epidural block|OTHER: Ultrasound-guided bilateral quadratus lumborum block|DRUG: Induction of general anaesthesia with propofol|DRUG: Muscle Relaxant|DRUG: Maintenance of general anaesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION