pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Spanish Pillbox App for Elderly Patients Taking Multiple Medications
Status: COMPLETED
Conditions: Diabetes|Hypertension
Interventions: DEVICE: Pillbox app named ALICE|OTHER: oral and written information
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of CAR-T Therapy in Older Patients
Status: RECRUITING
Conditions: Lymphoma|Refractory B-Cell Lymphoma|Lymphoma, B-Cell|DLBCL NOS|High-grade B-cell Lymphoma|Multiple Myeloma
Interventions: BEHAVIORAL: Activities of Daily Living/ADLs|BEHAVIORAL: Instrumental Activity of Daily Living|BEHAVIORAL: Timed Up and Go|BEHAVIORAL: Cognition|BEHAVIORAL: Geriatric Depression Scale|BEHAVIORAL: Social Support|BEHAVIORAL: Brief Test of Attention|BEHAVIORAL: Trail Making Test|BEHAVIORAL: Controlled Oral Word Association Test|BEHAVIORAL: Hopkins Verbal Learning Test-Revised|OTHER: Blood draw
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparative Study Between Autologous Adipose Tissue Graft Versus Microfracture for Treatment of Articular Cartilage Defects
Status: NOT_YET_RECRUITING
Conditions: Knee Osteoarthritis
Interventions: PROCEDURE: cartilage regeneration technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Genetic Changes in Patients With Non-Small Cell Lung Cancer Who Are Receiving Vinorelbine and Gemcitabine Before Surgery
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DRUG: gemcitabine hydrochloride|DRUG: vinorelbine ditartrate|GENETIC: cytogenetic analysis|GENETIC: loss of heterozygosity analysis|GENETIC: microarray analysis|PROCEDURE: conventional surgery|PROCEDURE: neoadjuvant therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: |Primary Purpose: TREATMENT
Clinical trial: Determining the Role of Social Reward Learning in Social Anhedonia
Status: RECRUITING
Conditions: Psychosis
Interventions: BEHAVIORAL: Motivational Interviewing|BEHAVIORAL: Nutrition Didactic Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of Intravenous Administration of Allogeneic Adipose-Derived Mesenchymal Stem Cells for COVID-19-Induced Acute Respiratory Distress
Status: WITHDRAWN
Conditions: Covid19|ARDS
Interventions: DRUG: COVI-MSC|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Anti-Inflammatory Diet in BRC Patients on Aromatase Inhibitors
Status: RECRUITING
Conditions: Breast Cancer
Interventions: DIETARY_SUPPLEMENT: Supplement|DIETARY_SUPPLEMENT: AI diet|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: FMT in Cirrhosis and Hepatic Encephalopathy
Status: COMPLETED
Conditions: Cirrhosis|Hepatic Encephalopathy
Interventions: DRUG: Fecal Microbial transplant Capsules|DRUG: Fecal Microbial Transplant Enema|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Study of Nipocalimab or Intravenous Immunoglobulin (IVIG) in Pregnancies At Risk of Fetal and Neonatal Alloimmune Thrombocytopenia (FNAIT)
Status: NOT_YET_RECRUITING
Conditions: Thrombocytopenia, Neonatal Alloimmune
Interventions: DRUG: Nipocalimab|DRUG: Intravenous immunoglobulins (IVIG)|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Utility of 18FDOPA PET/MRI for Focal Hyperinsulinism
Status: RECRUITING
Conditions: Hyperinsulinism
Interventions: DRUG: 18F-Fluoro Dopa PET/MRI Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Uncemented Hemiarthroplasty, Radiological Features Comparing Lateral Versus Anterolateral Approach
Status: COMPLETED
Conditions: Femoral Neck Fractures|Hemiarthroplasty|Heterotopic Ossification
Interventions: PROCEDURE: Hemiarthroplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Long Pulse Versus Short Pulse Laser Dusting for Renal Stones
Status: WITHDRAWN
Conditions: Kidney Stone|Ureter Stone|Renal Stone
Interventions: DEVICE: Short Pulse Duration|DEVICE: Long Pulse Duration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: VOICE Study in China 'Towards a Partnership Between Parents of Very Premature Infants and Healthcare Professionals'
Status: UNKNOWN
Conditions: Emotional Stress|Parents|Family Separation|Neonatal Intensive Care|Parents Support|Family Centered Care|Infant ALL
Interventions: BEHAVIORAL: VOICE care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of Tomosynthesis for Characterization and the Management of Breast Lesions
Status: UNKNOWN
Conditions: Breast Neoplasms|Tomosynthesis|BRCA1 Protein|BRCA2 Protein
Interventions: DEVICE: Standard mammography|DEVICE: Standard mammography and tomosynthesis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Assessing a Endoscopic Mucosal Resection Site Using Different Endoscopic Imaging Methods
Status: COMPLETED
Conditions: Post-endoscopic Mucosal Resection of Colon Polyps
Interventions: DEVICE: Olympus CF190 Colonoscope High definition white light|DEVICE: Olympus CF190 Colonoscope White light with near focus|DEVICE: Olympus CF190 Colonoscope Narrow band imaging|DEVICE: Olympus CF190 Colonoscope Narrow band imaging with near focus|PROCEDURE: Biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Three Dose Levels of CP-690,550 Monotherapy Versus Placebo, Administered Orally Twice Daily (BID) for 6 Weeks
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: CP-690,550|DRUG: CP-690,550|DRUG: CP-690,550|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Naldemedine on Opioid-induced Bowel Dysfunction
Status: RECRUITING
Conditions: Opioid-Induced Bowel Dysfunction|Constipation
Interventions: DRUG: Naldemedine|DRUG: Placebo|DRUG: Tramadol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Dose Escalation Trial of SBRT After Induction Chemotherapy for Locally Advanced Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DRUG: FOLFIRINOX or gemcitabine/abraxane|RADIATION: SBRT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial of Group Psychotherapy for Veterans and Military Personnel With Post Traumatic Stress Disorder (PTSD)
Status: COMPLETED
Conditions: Posttraumatic Stress Disorder|Depression|Insomnia Disorder
Interventions: BEHAVIORAL: Cognitive Behavioral Social Rhythm Group Therapy|BEHAVIORAL: Present Centered Group Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: To Confirm Equivalent Bronchodilator Efficacy of the Test Product Compared to the Reference Product
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Budesonide/Formoterol Easyhaler 320/9 ug/inhalation 4 inh|DRUG: Budesonide/Formoterol Easyhaler 320/9 ug/inhalation 1 inh|DRUG: Symbicort Turbuhaler 320/9 ug/inhalation 4 inh|DRUG: Symbicort Turbuhaler 320/9 ug/inhalation 1inh|DRUG: Placebo Symbicort Turbuhaler 320/9 ug/inhalation 4 inh|DRUG: Placebo Budesonide/Formoterol Easyhaler 320/9 ug/inhalation 4 inh|DRUG: Placebo Budesonide/Formoterol Easyhaler 320/9 ug/inhalation 1 inh|DRUG: Placebo Symbicort Turbuhaler 320/9 ug/inhalation 1 inh
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Real World Effectiveness of Combining an Employer-based Weight Management Program With Medication for Chronic Weight Management in Employees With Obesity
Status: COMPLETED
Conditions: Obesity
Interventions: OTHER: Weight Management Program (WMP)|DRUG: Medication for chronic weight management (Rx)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigation of Mifepristone (RU486) on Stress Sensitivity and Relapse Prevention in Cocaine Dependent Patients
Status: COMPLETED
Conditions: Cocaine Dependence
Interventions: DRUG: Mifepristone|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: China Research for Severe Spontaneous Intracerebral Hemorrhage（CRISIH）
Status: RECRUITING
Conditions: Severe Spontaneous Intracranial Hemorrhage|Long-term Antiplatelet Treatment|Emergency Surgery|Complications
Interventions: PROCEDURE: Emergency neurosurgery|PROCEDURE: Conservative treatment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Analysis of Orthodontic Tooth Movement Using 3D Imaging
Status: COMPLETED
Conditions: Tooth Crowding|Dental Crowding|Malocclusion
Interventions: DEVICE: .014"|DEVICE: .016"|DEVICE: Twin brackets|DEVICE: Self-ligating brackets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neural Correlates of Hypoalgesia Driven by Observation
Status: RECRUITING
Conditions: Pain|Virtual Reality|Placebo
Interventions: DRUG: Naloxone|OTHER: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Investigating the Influence of Semaglutide on the Pharmacokinetics of Single Doses of Atorvastatin and Digoxin in Healthy Subjects
Status: COMPLETED
Conditions: Diabetes|Healthy
Interventions: DRUG: semaglutide|DRUG: digoxin|DRUG: atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Characterisation of the Immune Response to SARS-CoV-2 Infection / COVID-19 in Type 1 Diabetes
Status: COMPLETED
Conditions: SARS-CoV2 Infection Common Pathogens|Diabetes Mellitus, Type 1
Interventions: PROCEDURE: venous blood sample
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study to Evaluate BIIB059 (Litifilimab) in Cutaneous Lupus Erythematosus (CLE) With or Without Systemic Lupus Erythematosus (SLE)
Status: COMPLETED
Conditions: Systemic Lupus Erythematosus|Active Cutaneous Lupus Erythematosus
Interventions: DRUG: BIIB059 (litifilimab)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Dose Escalation Study of LNA-i-Mir-221 for Cancer Treatment
Status: COMPLETED
Conditions: Multiple Myeloma, Refractory|Hepatocarcinoma|Advanced Solid Tumor
Interventions: BIOLOGICAL: LNA-i-miR-221
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Web-based Oncofertility Support Tool for Reproductive-age Women With Breast Cancer
Status: COMPLETED
Conditions: Breast Neoplasm Female|Fertility Preservation
Interventions: DEVICE: Web-based oncofertility support tool
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study to Evaluate the Efficacy and Safety of PANZYGA in Pediatric Patients With Chronic Immune Thrombocytopenia (ITP)
Status: TERMINATED
Conditions: Chronic Immune Thrombocytopenia
Interventions: BIOLOGICAL: Panzyga
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Validation of the Gugging Swallowing Screen for the Intensive Care Unit
Status: COMPLETED
Conditions: Dysphagia
Interventions: OTHER: Gugging swallowing screen - ICU (GUSS-ICU) index test|OTHER: Flexible Endoscopic Evaluation of Swallowing (FEES) reference test
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: "Electromagnetical Stimulation of Phrenic Nerve to Generate Contraction of the Diaphragm"
Status: COMPLETED
Conditions: Healthy Subjects|Elective Surgical Procedure
Interventions: DEVICE: Stimit Activator
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Feasibility of Home Instillation of UGN-102 for Treatment of Low-Grade (LG) Non-Muscle-Invasive Bladder Cancer (NMIBC)
Status: COMPLETED
Conditions: Bladder Cancer|Urothelial Carcinoma|Urothelial Carcinoma Bladder
Interventions: DRUG: UGN-102
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose Escalation Study to Determine the Maximum Tolerated Dose of the Combination of Ruxolitinib and Bortezomib in Patients With Relapsed or Refractory Lymphoma
Status: COMPLETED
Conditions: Hodgkin's Lymphoma|Lymphoma, Non-Hodgkin
Interventions: DRUG: Bortezomib|DRUG: Ruxolitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Myofascial Trigger Point Dry Cupping on Plantar Heel Pain
Status: COMPLETED
Conditions: Plantar Fasciitis|Heel Spur Syndrome|Chronic Plantar Fasciitis
Interventions: DEVICE: Dry cupping|OTHER: Stretching exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Directional Versus Nondirectional DBS for ET
Status: UNKNOWN
Conditions: Essential Tremor
Interventions: DEVICE: Deep brain stimulation of the VIM Thalamic nuclei
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Methylsulfonylmethane on Knee Laxity
Status: COMPLETED
Conditions: Ligament Injury|Ligament; Laxity|Tendon Rupture|Tendon Injuries
Interventions: DIETARY_SUPPLEMENT: methylsulfonylmethane|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Texas Childhood Obesity Research Demonstration (TX CORD) Project -Primary Prevention Study
Status: COMPLETED
Conditions: Pediatric Obesity
Interventions: BEHAVIORAL: Enhanced CATCH Elementary School Program|BEHAVIORAL: CATCH Early Childhood (CEC)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Immunogenicity, Safety of Measles-mumps-rubella-varicella Vaccine (MeMuRu-OKA) Compared to Priorix™ Given With Varilrix™
Status: COMPLETED
Conditions: Mumps|Rubella|Measles|Varicella
Interventions: BIOLOGICAL: MeMuRu-OKA (study vac)|BIOLOGICAL: MMR, Varicella vacc (control)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Methylprednisolone on Orthostatic Intolerance and Heart Rate Variability in Hip-arthroplasty Patients
Status: COMPLETED
Conditions: Osteoarthrosis
Interventions: DRUG: Methylprednisolone|DRUG: Isotonic Sodium Chloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Venetoclax Combined With Homoharringtonine and Cytarabine in Induction for AML
Status: RECRUITING
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Venetoclax|DRUG: Homoharringtonine|DRUG: Cytarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I Study of HY209 Gel in Healthy Male Volunteers for Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: HY209
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Better Birth Outcomes Through Technology, Education, and Reporting
Status: RECRUITING
Conditions: Pregnancy|Maternal Anemia|Pre-Term Birth|Hypertensive Disorders
Interventions: BEHAVIORAL: BETTER: motivational interviewing and text messaging|BEHAVIORAL: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: IONTOPHORESIS Versus Ultrasound in Mechanical Neck Pain
Status: UNKNOWN
Conditions: Trigger Point Pain, Myofascial
Interventions: OTHER: Magnesium Sulphate Iontophoresis +conventional therapy|OTHER: High- Power Pain Threshold Ultrasound +conventional therapy|OTHER: conventional theapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of Evacetrapib in High-Risk Vascular Disease
Status: TERMINATED
Conditions: Cardiovascular Diseases
Interventions: DRUG: Evacetrapib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Physical Activity and Protein Supplementation After Bariatric Surgery (PAPAB)
Status: COMPLETED
Conditions: Bariatric Surgery Candidate
Interventions: DIETARY_SUPPLEMENT: Protein|DIETARY_SUPPLEMENT: Placebo|BEHAVIORAL: Computer-assisted exercise|BEHAVIORAL: Usual exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Post-approval Study of the DURALOC® Option Ceramic-on-Ceramic Hip Prosthesis System
Status: TERMINATED
Conditions: Non-inflammatory Joint Disease|Osteoarthritis|Avascular Necrosis|Congenital Hip Dysplasia|Post-traumatic Arthritis
Interventions: DEVICE: Total hip replacement/arthroplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intravitreal Bevacizumab vs Photocoagulation for Proliferative Diabetic Retinopathy
Status: WITHDRAWN
Conditions: Diabetic Retinopathy
Interventions: DRUG: intravitreal injection of bevacizumab|PROCEDURE: panretinal photocoagulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intralipid Therapy for Women 35-40 Years With Positive Natural Killer Cells Undergoing Intracytoplasmic Sperm Injection (ICSI)
Status: TERMINATED
Conditions: Infertility
Interventions: DRUG: Intralipid infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Implementation of a Protocol for the Transdifferentiation of Buccal Mucosal Epithelium Into Corneal Epithelium
Status: RECRUITING
Conditions: Limbal Stem Cell Deficiency
Interventions: PROCEDURE: Conjunctival reconstruction
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: RAPA-201 Therapy of Solid Tumors
Status: RECRUITING
Conditions: Solid Tumor|Breast Cancer|Small Cell and Non-small Cell Lung Cancer|Triple Negative Breast Cancer|Gastric Cancer|Esophageal Adenocarcinoma|Gastric Junction Adenocarcinoma|Esophageal Squamous Cell Carcinoma|Head and Neck Cancer|Squamous Cell Carcinoma of Oral Cavity|Squamous Cell Carcinoma of Larynx|Squamous Cell Carcinoma of Nasopharynx|Squamous Cell Carcinoma of Other Specified Sites of Skin|Carcinoma of Unknown Primary|Bladder Cancer|Malignant Melanoma
Interventions: BIOLOGICAL: RAPA-201 Rapamycin Resistant T Cells|DRUG: Chemotherapy Prior to RAPA-201 Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Dispensing Clinical of Fanfilcon A Lens Against Lotrafilcon B Lens Over 1 Month Wear Per Lens
Status: COMPLETED
Conditions: Myopia
Interventions: DEVICE: fanfilcon A|DEVICE: lotrafilcon B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bleomycin, Etoposide, and Cisplatin in Treating Patients With Metastatic Germ Cell Cancer of the Testicles
Status: COMPLETED
Conditions: Drug/Agent Toxicity by Tissue/Organ|Testicular Germ Cell Tumor
Interventions: BIOLOGICAL: bleomycin sulfate|DRUG: cisplatin|DRUG: etoposide|PROCEDURE: management of therapy complications
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: HCQ in Resectable Localized Prostate Cancer
Status: NOT_YET_RECRUITING
Conditions: Resectable Localized Prostate Cancer
Interventions: DRUG: Hydroxychloroquine Sulfate 400Mg Tab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Transmuscular Quadratus Lumborum Block for Total Laparoscopic Hysterectomy.
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: Ropivacaine|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Short Term Results of Platelet-rich Plasma in the Treatment of Chronic Anal Fissure
Status: COMPLETED
Conditions: Anal Fissure Chronic|PRP
Interventions: BIOLOGICAL: prp injection|DRUG: Anrecta|BEHAVIORAL: sitz bath|DIETARY_SUPPLEMENT: nutrition regulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Phase II Trial of Sorafenib Combined With Concurrent HAIC for Hepatocellular Carcinoma
Status: COMPLETED
Conditions: Hepatocellular Carcinoma
Interventions: PROCEDURE: Hepatic arterial infusion chemotherapy|DRUG: Folfox Protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Exploratory Study of Erlotinib and SNDX-275 in Participants With Non-small Cell Lung Carcinoma Who Are Progressing on Erlotinib
Status: TERMINATED
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: Entinostat|DRUG: Erlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a 3-D Tomosynthesis Mammography System Used in Conjunction With Conventional 2-D Digital Mammography
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DEVICE: Tomosynthesis digital mammography imaging system
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: DIAGNOSTIC
Clinical trial: Drug Interaction of Vildagliptin (LAF237) With Voglibose in Japanese Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: Vildagliptin (LAF237)|DRUG: Voglibose|DRUG: Vildagliptin and Voglibose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: DS-8201a for trEatment of aBc, BRain Mets, And Her2[+] Disease
Status: COMPLETED
Conditions: Advanced Breast Cancer|HER2-positive Breast Cancer|Brain Metastases|Leptomeningeal Metastasis
Interventions: DRUG: Trastuzumab deruxtecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vitamin K2 and Vessel Calcification in Chronic Kidney Disease Patients
Status: UNKNOWN
Conditions: Kidney Diseases|Coronary Artery Calcification
Interventions: DRUG: Vitamin K2+10μg cholecalciferol|DRUG: Vitamin D
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Treatment Study Using Depot Naltrexone (1/6) Philadelphia Coord/Data Mgmt Site
Status: COMPLETED
Conditions: Opiate Addiction
Interventions: DRUG: Depot naltrexone|OTHER: Treatment as Usual (TAU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose-finding Study of Colchicine in Type 2 Diabetic Patients With Coronary Artery Disease
Status: COMPLETED
Conditions: Colchicine|Diabetes Mellitus, Type 2|Coronary Artery Disease|White Blood Cell|Inflammation|Diarrhea
Interventions: DRUG: Colchicine 0.5 mg|DRUG: Colchicine 0.25 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Cleft Palate Repair Using Alveolar Extension Technique on Eruption and Growth
Status: COMPLETED
Conditions: Cleft Palate
Interventions: PROCEDURE: Palatoplasty|DIAGNOSTIC_TEST: Addition silicone impression
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Incision Size and Architecture on Wound Stability and Astigmatism in Cataract Surgery: an Exploratory Study
Status: COMPLETED
Conditions: Cataract
Interventions: PROCEDURE: MICS-group|PROCEDURE: SICS-group|PROCEDURE: SICS pre-cut|PROCEDURE: SICS stab-incision
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: RP3 in Combination With 1L or 2L Therapy in Patients With Locally Advanced Unresectable or Metastatic HCC
Status: NOT_YET_RECRUITING
Conditions: Locally Advanced Hepatocellular Carcinoma|Recurrent Hepatocellular Carcinoma|Metastatic Hepatocellular Carcinoma
Interventions: BIOLOGICAL: RP3|BIOLOGICAL: atezolizumab|BIOLOGICAL: bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Zaleplon 10mg Capsules Under Fasting Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Zaleplon 10 mg Capsules|DRUG: Sonata® 10 mg Capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Non-Invasive Imaging of the Human Eye
Status: WITHDRAWN
Conditions: Willing and Able Subjects for Ocular Imaging
Interventions: DEVICE: 3D OCT-1|DEVICE: 3D OCT-2000|DEVICE: DRI OCT-1|DEVICE: NW-300|DEVICE: CT-1P|DEVICE: TRK-2P|DEVICE: SP-1P|DEVICE: SL-D701|DEVICE: MC-4S
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of Collagen-based Medical Device Treatment Combined With Physiotherapy in Subjects With Achilles Tendinopathy.
Status: RECRUITING
Conditions: Tendinopathy|Insertional Achilles Tendinopathy|Achilles Tendinopathy|Peritendinitis
Interventions: DEVICE: MD-Tissue Collagen Medical Device|OTHER: eccentric strengthening protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Nutritional Supplements and Hormonal Manipulations for Breast Cancer Prevention
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DIETARY_SUPPLEMENT: Lovaza 4gm oral|DRUG: Raloxifene 60 Mg Oral Tablet|DRUG: Raloxifene 30 Mg Oral Tablet|DRUG: Lovaza 4gm & Raloxifene 30mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Clinical Study Comparing the Pharmacokinetics and Pharmacodynamic Characteristics of Insulin Degludec Injection (RD15003) and Insulin Degludec Injection (Tresiba®) in Healthy Subjects
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: BIOLOGICAL: Insulin degludec injection, RD15003|BIOLOGICAL: Insulin degludec, Tresiba
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pectoralis (II) Block With Liposomal Bupivacaine vs Bupivacaine for Breast Surgery
Status: TERMINATED
Conditions: Pain, Postoperative
Interventions: DRUG: Liposomal bupivacaine right injection|DRUG: Liposomal bupivacaine left injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CT-FIRST: Cardiac Computed Tomography Versus Stress Imaging For Initial Risk STratification
Status: UNKNOWN
Conditions: Coronary Artery Disease|Chest Pain|Coronary Atherosclerosis|Stress Testing
Interventions: PROCEDURE: Cardiac CT Angiography|PROCEDURE: Stress Imaging Test (Stress Myocardial Perfusion Study or Stress Echocardiogram)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Phase 2, Multicenter, Randomized, Double-blind, Placebo Controlled Study for the Pain of Diabetic Peripheral Neuropathy
Status: COMPLETED
Conditions: Painful Diabetic Neuropathy
Interventions: DRUG: SKL11197|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SAbR For Oligometastatic Renal Cell Carcinoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Oligometastatic Renal Cell Carcinoma
Interventions: RADIATION: Stereotactic ablative body radiation (SABR)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I Safety and Immunogenicity Trial of UBI Microparticulate Monovalent HIV-1 MN Peptide Immunogen in HIV-1 Seronegative Human Subjects
Status: COMPLETED
Conditions: HIV Infections
Interventions: BIOLOGICAL: HIV-1 Peptide Vaccine, Microparticulate Monovalent
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: The VICTORY Trial: Virtual, Innovative, Postsurgical Care To Optimize Return Home for Older People With frailtY
Status: NOT_YET_RECRUITING
Conditions: Surgery|Frailty
Interventions: BEHAVIORAL: Virtual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Web App Technology for Boys and Parents: Improving HPV Vaccine Uptake
Status: COMPLETED
Conditions: Human Papillomavirus Virus|HPV
Interventions: BEHAVIORAL: Web App Intervention Group|BEHAVIORAL: Usual Customary Care Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluating the Impact of Incremental Doses of a Sugar Replacer Blend on Gastrointestinal Tolerance in Candies
Status: NOT_YET_RECRUITING
Conditions: Gastrointestinal Tolerance|Healthy Population
Interventions: OTHER: Low-sugar candies compared to regular sugar candies
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Sublingual Misoprostol In Medical Treatment of First Trimester Missed Miscarriage
Status: UNKNOWN
Conditions: Miscarriage
Interventions: DRUG: misoprostol 400 mcg|DRUG: misoprostol 800 mcg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Cognitive Ageing Nutrition and Neurogenesis (CANN) Trial
Status: COMPLETED
Conditions: Mild Cognitive Impairment|Subjective Memory Impairment
Interventions: DIETARY_SUPPLEMENT: fatty acid/flavonoid blend|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multidisciplinary and Personalized Care of Behavioral Disorders in Frontotemporal Lobar Degeneration.
Status: COMPLETED
Conditions: Frontotemporal Lobar Degeneration
Interventions: OTHER: 3 Home visits made by a psychologist
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Managing Acute Schizophrenia, a Comparison Between Two Atypical Antipsychotics
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Olanzapine Hydrochloride|DRUG: Risperidone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Tamoxifen Versus Etoposide After First Recurrence in GBM Patients
Status: RECRUITING
Conditions: Glioblastoma Multiforme
Interventions: DRUG: Tamoxifen|DRUG: Etoposide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized, Double Blinded, Placebo Control Clinical Trial of Pandemic Influenza Inactive Vaccine on Healthy Subjects
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: an inactivated whole virion H5N1 vaccine, adjuvanted
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Radiation Major Hepatectomy to Selectively Treat Large Unifocal Hepatocellular Carcinoma
Status: RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: PROCEDURE: Ablative radioembolization using Yttrium-90 resin microspheres
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sphenopalatine Ganglion Nerve Block vs. Elavil for Treatment of Transformed Migraines
Status: TERMINATED
Conditions: Transformed Migraine|Chronic Daily Headache
Interventions: PROCEDURE: SPG Block with 5% Lidocaine gel|DRUG: Amitriptyline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Ketorolac and Pregabalin Effects on breaSt Cancer (KePreSt)
Status: NOT_YET_RECRUITING
Conditions: Early-stage Breast Cancer|Estrogen-receptor-positive Breast Cancer
Interventions: PROCEDURE: Prospective data and sample collection|DRUG: Ketorolac 10 Mg Oral Tablet|DRUG: Pregabalin 75mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Immunogenicity and Tolerability of V503 Versus GARDASIL (V503-009)
Status: COMPLETED
Conditions: Human Papillomavirus
Interventions: BIOLOGICAL: V503|BIOLOGICAL: GARDASIL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of Erenumab in Pediatric Subjects With Chronic Migraine
Status: RECRUITING
Conditions: Migraine
Interventions: DRUG: Erenumab Dose 1|DRUG: Erenumab Dose 2|DRUG: Erenumab Dose 3|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Celecoxib or Observation After Radiation Therapy and Chemotherapy in Treating Patients With Stage II or Stage III Non-Small Cell Lung Cancer
Status: UNKNOWN
Conditions: Lung Cancer
Interventions: DRUG: celecoxib|DRUG: docetaxel|PROCEDURE: adjuvant therapy|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Coronary Artery Bypass Grafts or Percutaneous Coronary Intervention for High Risk Patients
Status: NOT_YET_RECRUITING
Conditions: IHD|LV Dysfunction
Interventions: PROCEDURE: PCI|PROCEDURE: CABG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Post Marketing Surveillance Study of Remicade in Patients With Chronic Inflammatory Diseases (P04840)
Status: COMPLETED
Conditions: Arthritis, Rheumatoid|Spondylitis, Ankylosing|Arthritis, Psoriatic|Psoriasis|Crohn's Disease
Interventions: BIOLOGICAL: Infliximab
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: In Utero Hematopoietic Stem Cell Transplantation for Alpha-thalassemia Major (ATM)
Status: ENROLLING_BY_INVITATION
Conditions: Alpha Thalassemia Major|Hemoglobinopathy; With Thalassemia|Hemoglobinopathies|Fetal Anemia|Fetal Hydrops|Alpha; Thalassemia|Thalassemia Major|Thalassemia Alpha|A-Thalassemia
Interventions: BIOLOGICAL: in utero hematopoietic stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of HBV Reactivation Between Patients With High HBV-DNA and Low HBV-DNA Loads Undergoing ICI and Concurrent Antiviral Prophylaxis: a Prospective Observational Study
Status: RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: ICI|DRUG: Antiviral Prophylaxis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Impact of the Nature and Interface of the Tracheostomy Cannula on Dyspnea in Patients Weaning From Artificial Ventilation in Weaning Unit
Status: NOT_YET_RECRUITING
Conditions: Prolonged Weaning
Interventions: DEVICE: low pressure tracheostomy cannulas|DEVICE: plated balloon tracheostomy cannulas
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Cytotoxic T Lymphocytes in Treating Patients With Malignancies With BK and/or JC Virus
Status: RECRUITING
Conditions: Acquired Immunodeficiency Syndrome|BK Virus Infection|Human Immunodeficiency Virus|JC Virus Infection|Malignant Neoplasm|Merkel Cell Carcinoma|Merkel Cell Polyomavirus Infection|Viral Encephalitis
Interventions: BIOLOGICAL: Allogeneic BK-specific Cytotoxic T-lymphocytes|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Effect of a Moderate CYP3A Inducer Efavirenz on Quizartinib Pharmacokinetics in Healthy Participants
Status: COMPLETED
Conditions: Healthy Subjects|Drug-drug Interaction|Pharmacokinetics|Quizartinib
Interventions: DRUG: Efavirenz|DRUG: Quizartinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Photon/Proton Radiation Therapy for Cancers of the Nasal Cavity and/or Paranasal Sinuses
Status: COMPLETED
Conditions: Cancers of Nasal Cavity|Cancers of Paranasal Sinuses
Interventions: OTHER: Xerostomia questionnaire
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Atomoxetine and Placebo in Children and Adolescents With ADHD and ODD
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder|Oppositional Defiant Disorder
Interventions: DRUG: atomoxetine hydrochloride|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Abdominal Aortic Aneurysm Stabilization With Truncal Cells: Controlled Clinical Trial With Historical Cohorts
Status: RECRUITING
Conditions: Aortic Aneurysm, Abdominal
Interventions: DRUG: Allogeneic adipose tissue-derived mesenchymal stem cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study to Investigate the Effect of Balovaptan on the QTC Interval in Healthy Subjects
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Balovaptan therapeutic dose Treatment A|DRUG: Balovaptan supra-therapeutic dose Treatment B|DRUG: Active control [moxifloxacin] on Day 2 Treatment C|DRUG: Active control [Moxifloxacin] on Day 15 Treatment D|DRUG: Placebo for Balovaptan Treatment C|DRUG: Placebo for Balovaptan Treatment D|DRUG: Placebo for Moxifloxacin Treatment A|DRUG: Placebo for Moxifloxacin Treatment B|DRUG: Moxifloxacin Treatment C|DRUG: Placebo for Moxifloxacin Treatment C|DRUG: Placebo for Moxifloxacin Treatment D|DRUG: Moxifloxacin Treatment D
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Influence of Respiratory Muscle Training on Objective and Subjective Training Load Measures in Triathletes
Status: COMPLETED
Conditions: Athletic Performance
Interventions: BEHAVIORAL: Respiratory Muscle Training - VIH|BEHAVIORAL: Respiratory Muscle Training - ITPL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Clinical Trial to Evaluate Efficacy and Safety of Two Different Formulations of Topical Calcipotriol in Patients With Mild to Moderate Plaque Psoriasis
Status: COMPLETED
Conditions: Mild to Moderate Plaque Psoriasis
Interventions: DRUG: Calcipotriol/AKVANO, 50 μg/g cutaneous solution|DRUG: Calcipotriol Ointment 50 micrograms/g|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of IMMU-130 in Patients With Relapsed/Refractory Colorectal Cancer
Status: COMPLETED
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: IMMU-130
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Mitoxantrone Hydrochloride Liposome Injection in the Treatment of Neuromyelitis Optica Spectrum Disorder (NMOSD)
Status: COMPLETED
Conditions: Neuromyelitis Optica Spectrum Disorder
Interventions: DRUG: Mitoxantrone Hydrochloride Liposome Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Cerebellum or Supplementary Motor Area Functional Inactivation on Gait and Balance Control
Status: COMPLETED
Conditions: Transcranial Magnetic Stimulation
Interventions: OTHER: transcranial magnetic stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety and Efficacy of a New Formulation of Bimatoprost/Timolol Ophthalmic Solution Compared With Bimatoprost/Timolol Ophthalmic Solution in Patients With Glaucoma or Ocular Hypertension
Status: COMPLETED
Conditions: Glaucoma|Ocular Hypertension
Interventions: DRUG: bimatoprost /timolol formulation A fixed combination ophthalmic solution|DRUG: bimatoprost/timolol fixed combination ophthalmic solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Gamma Tocopherol-enriched Supplement on Lower Airway Responses to Inhaled Wood Smoke in Healthy Adults
Status: COMPLETED
Conditions: Airway Inflammation|Asthma
Interventions: DRUG: Gamma Tocopherol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: First-in-man Safety and Efficacy Trial of a Novel Non-invasive Bladder Emptying Device: The NIBED Study
Status: TERMINATED
Conditions: Urinary Retention
Interventions: DEVICE: Non-invasive bladder emptying device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Metformin and Liraglutide in Obese Subjects With Type 2 Diabetes Previously Treated With an Oral Hypoglycemic Agent
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: liraglutide|DRUG: metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Renal Effect of Stribild or Other Tenofovir DF-containing Regimens Compared to Ritonavir-boosted Atazanavir Plus Abacavir/Lamivudine in Antiretroviral Treatment-naive HIV-1 Infected Adults
Status: COMPLETED
Conditions: HIV-1 Infection
Interventions: DRUG: STB|DRUG: TVD|DRUG: ATR|DRUG: RTV|DRUG: ATV|DRUG: ABC/3TC|DRUG: Iohexol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT