pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Treatment of Facial Burns With Flammacerium Compared to Flammazine and the Impact of Facial Burns on Psychosocial Wellbeing
Status: COMPLETED
Conditions: Burns
Interventions: DRUG: ceriumnitrate silversulfadiazine (flammacerium)|DRUG: silversulfadiazine (flammazine)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: First In Human, Phase 1 Study of AG013736 In Patients With Solid Tumors
Status: COMPLETED
Conditions: Advanced Solid Tumors
Interventions: DRUG: AG-013736|DRUG: AG-013736|DRUG: AG-013736|DRUG: AG-013736|DRUG: AG-013736|DRUG: AG-013736
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Positive Feeding of the Preterm Infant
Status: NOT_YET_RECRUITING
Conditions: Preterm Infant|Breast Feeding|Bottle Feeding|Enteral Feeding|Cue Based Feeding|Develomentally Supportive Care
Interventions: OTHER: Positive feeding of the preterm infant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: An Open-Label Extension Study to Evaluate the Safety and Effectiveness of RWJ 333369 in Patients With Epilepsy
Status: COMPLETED
Conditions: Epilepsy|Epilepsies, Partial
Interventions: DRUG: RWJ 333369:
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chidamide With PET Regimen for Angioimmunoblastic T Cell Lymphoma (PET: Prednisone, Etoposide and Thalidomide)
Status: UNKNOWN
Conditions: Angioimmunoblastic T-cell Lymphoma
Interventions: DRUG: Chidamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gastric- Versus Jejunal Feeding Tubes in Alcoholic Liver Diseases
Status: COMPLETED
Conditions: Malnutrition|Liver Diseases, Alcoholic
Interventions: DEVICE: Gastric tube (Nutricia Flocare® Pur Tube Enlock)|DEVICE: Jejunal tube (Nutricia Flocare® Bengmark®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of the Third Dose Immunization Schedule of COVID-19 Inactivated Vaccine, (Vero Cells) Based on Different COVID-19 Inactivated Vaccine in Adults Aged 18 Years and Above
Status: UNKNOWN
Conditions: SARS-CoV-2 Infection
Interventions: BIOLOGICAL: SARS-CoV-2 Vaccine, Inactivated (Vero Cell)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Long-Term Study of TS-142 in Patients With Insomnia
Status: COMPLETED
Conditions: Patients With Insomnia
Interventions: DRUG: TS-142 5 mg|DRUG: TS-142 10 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Minocycline Hydrochloride in Reducing Chemotherapy Induced Depression and Anxiety in Patients With Stage I-III Breast Cancer
Status: UNKNOWN
Conditions: Anxiety Disorder|Depression|Recurrent Breast Cancer|Stage IA Breast Cancer|Stage IB Breast Cancer|Stage II Breast Cancer|Stage IIIA Breast Cancer|Stage IIIB Breast Cancer|Stage IIIC Breast Cancer
Interventions: DRUG: minocycline hydrochloride|OTHER: placebo|OTHER: laboratory biomarker analysis|OTHER: Questionnaire administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Ablation at Virtual-hEart pRedicted Targets for VT
Status: RECRUITING
Conditions: Ventricular Tachycardia|Ischemic Cardiomyopathy
Interventions: DEVICE: Virtual Heart Guided Ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Assess the Efficacy and Safety of Tacrolimus Ointment Treatment of Atopic Dermatitis in Adult Patients
Status: COMPLETED
Conditions: Dermatitis, Atopic
Interventions: DRUG: tacrolimus ointment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Slow-SPEED-NL: Slowing Parkinson's Early Through Exercise Dosage-Netherlands
Status: RECRUITING
Conditions: Parkinson Disease|Prodromal Stage|Neurodegenerative Diseases|Parkinsonian Disorders|REM Sleep Behavior Disorder|Basal Ganglia Diseases|Central Nervous System Diseases|Synucleinopathies|Nervous System Diseases|Cerebral Disorder|Brain Diseases
Interventions: BEHAVIORAL: Increase of physical activity volume and intensity with the use of a motivational smartphone application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Polidocanol Versus Glucose Treatment of Telangiectasia Trial
Status: COMPLETED
Conditions: Varicose Veins|Telangiectasis
Interventions: DRUG: Glucose|DRUG: Polidocanol with Glucose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial Evaluating Postop Pain and Muscle Strength Among Regional Anesthesia Techniques for Ambulatory ACL Reconstruction
Status: COMPLETED
Conditions: Rupture of Anterior Cruciate Ligament|Tear of Anterior Cruciate Ligament
Interventions: DRUG: Mepivacaine|PROCEDURE: adductor canal continuous nerve catheter|DRUG: Normal Saline as bolus followed by bupivacaine|PROCEDURE: adductor canal nerve block|DRUG: ropivacaine and dexamethasone|DRUG: Propofol|DRUG: Fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Carboxylesterase 1 Genetic Variation and Methylphenidate in ADHD
Status: RECRUITING
Conditions: ADHD|Attention Deficit Hyperactivity Disorder
Interventions: DRUG: Methylphenidate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Family-Focused Therapy for Individuals at High Clinical Risk for Psychosis: A Confirmatory Efficacy Trial
Status: RECRUITING
Conditions: Psychotic Disorders|Prodromal Symptoms|Prodromal Schizophrenia|Psychosis|Family
Interventions: BEHAVIORAL: Family Focused Therapy for Clinical High Risk Youth (FFT-CHR)|BEHAVIORAL: Enhanced Care (EC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Heated Chemotherapy for Cancers That Have Spread to the Chest Cavity
Status: COMPLETED
Conditions: Pleural Metastases|Breast Cancer|Colon Cancer|Ovarian Cancer|Uterine Cancer|Renal Cell Cancer|Thymic Cancer
Interventions: PROCEDURE: Surgical debulking and Intrathoracic Hyperthermic Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sleep Profile of Patients With Septo-optic Dysplasia
Status: RECRUITING
Conditions: Septo-Optic Dysplasia|Agenesis of Corpus Callosum|Blindness
Interventions: DIAGNOSTIC_TEST: Actigraphy, blood and salivary sample, and sleep evaluation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Metabolic and Molecular Responses Under the Effect of Taurine Supplementation With and Without Multicomponent Training
Status: UNKNOWN
Conditions: Sarcopenic Obesity
Interventions: DIETARY_SUPPLEMENT: Taurine and Exercise (Tau+Ex)|OTHER: Placebo and Exercise (PL+Ex)|DIETARY_SUPPLEMENT: Taurine (Tau)|OTHER: Placebo (PL)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison Study of Sentinel Lymph Node Biopsy by Multimodal Method in Breast Cancer
Status: COMPLETED
Conditions: Breast Neoplasms
Interventions: DEVICE: the mixture including indocyanine green|DEVICE: radioisotope
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Incidence of IV Fluid Over-administration in Pediatric Dental Surgeries When Infusion Pumps Are Employed
Status: COMPLETED
Conditions: Dental Caries
Interventions: DEVICE: Hospira plum pump|DEVICE: Gravity drip device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of a Psycho-cognitive Nursing Intervention on Patients' Outcomes in Critical Illness
Status: UNKNOWN
Conditions: Critical Illness|Stress|Inflammatory Response
Interventions: BEHAVIORAL: Massage, Relaxation, Guided imagery and music listening.|OTHER: No Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SIKAMIC (SIklos on Kidney Function and AlbuMInuria Clinical Trial)
Status: COMPLETED
Conditions: Sickle Cell Disease
Interventions: DRUG: Hydroxycarbamide|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study of Re-treatment of Myelofibrosis Patients With Ruxolitinib/Jakavi After Treatment Interruption Due to Loss of Response and/or Adverse Event (ReTreatment Trial)
Status: TERMINATED
Conditions: Primary Myelofibrosis
Interventions: DRUG: Ruxolitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigation of a Long-Acting Follicle Stimulating Hormone in Infertile Women Undergoing Assisted Reproductive Technology (ART)
Status: COMPLETED
Conditions: Infertility
Interventions: DRUG: AS900672-Enriched 50 microgram (mcg)|DRUG: AS900672-Enriched 100 mcg|DRUG: AS900672-Enriched 150 mcg|DRUG: Follitropin alfa 150 international unit (IU)|DRUG: Recombinant human chorionic gonadotropin (r-hCG)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Benefit of Hypothermia in OHCA Complicating AMI
Status: ACTIVE_NOT_RECRUITING
Conditions: Out-Of-Hospital Cardiac Arrest|Myocardial Infarction, Acute|Hypothermia Neonatal
Interventions: DEVICE: Hypothermia
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intraoperative Electron Radiotherapy in Rectal Cancer - A Feasibility Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Locally Advanced Rectal Cancer|Locally Recurrent Rectal Cancer
Interventions: RADIATION: Intraoperative Electron Radiotherapy (IOERT)|PROCEDURE: Extended Margin Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Dasatinib With Bortezomib (Velcade®) and Dexamethasone for Multiple Myeloma
Status: TERMINATED
Conditions: Multiple Myeloma
Interventions: DRUG: Dasatinib|DRUG: Bortezomib|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Compare the Effects of Herbal Medicines With Traditional Allopathic Medicines in Cases of Patients With Metabolic Syndrome
Status: RECRUITING
Conditions: Metabolic Syndrome
Interventions: DRUG: rosuvastatin, METFORMIN, Sitagliptin, Telmisartan, Cinnamon. garlic, Ginger, Methi dana, Arjun
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Skin-to-Skin Contact Based on Clinical Guidelines
Status: NOT_YET_RECRUITING
Conditions: Breastfeeding|Newborn
Interventions: OTHER: Skin contact immediately after birth|OTHER: Very Early Skin contact|OTHER: Early Skin contact
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Awareness and Self-Compassion Enhancing Narcolepsy Treatment
Status: COMPLETED
Conditions: Narcolepsy|Narcolepsy Without Cataplexy|Narcolepsy With Cataplexy
Interventions: BEHAVIORAL: Brief MBI|BEHAVIORAL: Standard MBI|BEHAVIORAL: Extended MBI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase II Pilot Study to Assess the Presence of Molecular Factors Predictive for Hematologic Response in Myelodysplastic Syndrome Patients Receiving Deferasirox Therapy.
Status: TERMINATED
Conditions: Myelodysplastic Syndrome
Interventions: PROCEDURE: Bone marrow aspirate|DRUG: Deferasirox
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Hyaluronic Acid Gels for Lower Lid Retraction
Status: WITHDRAWN
Conditions: Ectropion
Interventions: PROCEDURE: Hyaluronic acid|PROCEDURE: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Studying the Effect of Mediterranean Diet on Insulin Resistance Among Obese Children and Adolescents
Status: UNKNOWN
Conditions: Obesity, Childhood|Insulin Resistance
Interventions: OTHER: the effect of Mediterranean diet on insulin sensitivity among obese children and adolescents aged
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Use of D5LR Versus LR for Induction of Labor and Time to Delivery in Multiparous and Primiparous Patient's With Favorable and Unfavorable Bishop's Scores
Status: COMPLETED
Conditions: Induction of Labor Affected Fetus / Newborn
Interventions: OTHER: Lactated ringers|OTHER: 5% dextrose lactated ringers
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison Between Different Types of Oxygen Treatment Following Traumatic Brain Injury
Status: COMPLETED
Conditions: Traumatic Brain Injury
Interventions: PROCEDURE: Hyperbaric Oxygen Treatment (HBOT)|PROCEDURE: Enhanced Oxygen Treatment (Enhanced FiO2)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic and Safety Trial of Intravenous Levetiracetam in the Treatment of Neonatal Seizures
Status: COMPLETED
Conditions: Seizures|Disorder of Fetus or Newborn
Interventions: DRUG: Low dose levetiracetam|DRUG: High dose levetiracetam
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nutritional Rehabilitation in Senegalese HIV-infected Children and Adolescents
Status: COMPLETED
Conditions: Malnutrition|HIV/AIDS
Interventions: DIETARY_SUPPLEMENT: Plumpy Nut|DIETARY_SUPPLEMENT: Plumpy Sup
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Aerobic Exercising Program on Respiratory Muscle Strength in Patients With Adolescent Idiopathic Scoliosis
Status: COMPLETED
Conditions: Adolescent Idiopathic Scoliosis
Interventions: OTHER: Aerobic exercise program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Arginase Inhibition and Microvascular Endothelial Function in Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: OTHER: N-hydroxy-nor-L-arginine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Assessing the Impact of Lipoprotein (a) Lowering With Pelacarsen (TQJ230) on Major Cardiovascular Events in Patients With CVD
Status: ACTIVE_NOT_RECRUITING
Conditions: Cardiovascular Disease and Lipoprotein(a)
Interventions: DRUG: TQJ230|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of High-intensity Interval Training (HIIT) in Recent Onset Polymyositis and Dermatomyositis
Status: UNKNOWN
Conditions: Polymyositis|Dermatomyositis
Interventions: OTHER: High-intensity interval training (HIIT) - myositis|OTHER: Standard low-intensity home exercise|OTHER: High-intensity interval training (HIIT) - healthy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Effectiveness of a New Way of Organizing Primary Health Care to Improve the Management of Alzheimer's Disease
Status: RECRUITING
Conditions: Alzheimer's Disease
Interventions: OTHER: Multidimensional fragility index questionnaire RAI-Home Care|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Use Feasibility of the iThermonitor in Pediatrics Patients on Myelosuppresive Therapies
Status: COMPLETED
Conditions: Acute Lymphocytic Leukemia|Acute Myeloid Leukemia|Non-Hodgkin Lymphoma
Interventions: DEVICE: iThermonitor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Intraperitoneal Atomization of Levobupivacaine During Gynaecological Laparoscopic Procedures ; Impact on Pain, Opioid Use and Length of Recovery Room Stay (IPLA).
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: DRUG: Standard Injection of Levobupivacaine in portal sites.|DRUG: Additional injection of 0,5% levobupivacaine.|DRUG: Intraperitoneal atomization of levobupivacaine.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect Of Tele-Yoga On Aerobic Capacity, Respiratory Muscle Strength, And Cognitive Performance In Patients With OSAS
Status: COMPLETED
Conditions: Obstructive Sleep Apnea
Interventions: OTHER: Tele - Yoga|OTHER: Thoracic Expansion Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Perioperative Rescue Transesophageal Echocardiography in Intensive and Critical Status
Status: RECRUITING
Conditions: Transesophageal Echocardiography
Interventions: DIAGNOSTIC_TEST: The PReTEE group|DIAGNOSTIC_TEST: The conventional TEE group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Randomized Controlled Trial Comparing Surgical Decompression With an Interlaminar Implant in Patients With Intermittent Neurogenic Claudication Caused by Lumbar Stenosis
Status: COMPLETED
Conditions: Intermittent Neurogenic Claudication (INC) as a Result of Spinal Stenosis
Interventions: PROCEDURE: Decompression
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of BL-M17D1 in Patients With Locally Advanced or Metastatic HER2 Positive/Lower Expression Gastrointestinal Cancer and Other Solid Tumors
Status: RECRUITING
Conditions: Esophageal Cancer|Gastric Cancer|Pancreatic Cancer|Colorectal Cancer|Solid Tumor
Interventions: DRUG: BL-M17D1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Effectiveness of Lamivudine When Given Once a Day Versus Twice a Day in Combination With Other Anti-HIV Drugs in HIV-Infected Adults Who Have Never Received Anti-HIV Drugs
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Efavirenz|DRUG: Lamivudine|DRUG: Zidovudine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of ABT-493/ABT-530 in Japanese Adults With Chronic Hepatitis C Virus Infection
Status: COMPLETED
Conditions: Chronic Hepatitis C Virus|Hepatitis C Virus
Interventions: DRUG: ABT-493/ABT-530|DRUG: OBV/PTV/r
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rituximab, Bendamustine Hydrochloride, and Bortezomib Followed by Rituximab and Lenalidomide in Treating Older Patients With Previously Untreated Mantle Cell Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Lymphoma|Neurotoxicity|Therapy-related Toxicity
Interventions: BIOLOGICAL: rituximab|DRUG: bendamustine hydrochloride|DRUG: bortezomib|DRUG: lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Leflunomide in Treating Patients With Relapsed or Refractory Multiple Myeloma
Status: COMPLETED
Conditions: Recurrent Plasma Cell Myeloma|Refractory Plasma Cell Myeloma
Interventions: OTHER: Laboratory Biomarker Analysis|DRUG: Leflunomide|OTHER: Pharmacological Study
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Poly-ICLC to Prevent Respiratory Viral Infections A Safety Study
Status: COMPLETED
Conditions: Influenza|Severe Acute Respiratory Distress Syndrome|Smallpox|Ebola|Unknown Respiratory Viruses
Interventions: DRUG: Poly-ICLC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: |Primary Purpose: TREATMENT
Clinical trial: Prognostic Evaluation of 18fmiso Pet-ct in Head and Neck Cancer
Status: COMPLETED
Conditions: Cancer of Head and Neck|Head and Neck Neoplasms
Interventions: RADIATION: Positon Emission Tomography using 18F-FMISO
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: DAHANCA 19: The Importance of the EGFr-inhibitor Zalutumumab for the Outcome After Curative Radiotherapy for HNSCC
Status: COMPLETED
Conditions: Cancer of the Head and Neck
Interventions: RADIATION: Radiotherapy|DRUG: Zalutumumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of CBT-001 Ophthalmic Solution in Patients With Pterygium
Status: COMPLETED
Conditions: Pterygium
Interventions: DRUG: CBT-001 single dose|DRUG: Vehicle|DRUG: CBT-001 Multi-dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Prospective Study on the Long-Term Vascular Burden in Thrombotic Thrombocytopenic Purpura Patients
Status: RECRUITING
Conditions: Thrombotic Thrombocytopenic Purpura
Interventions: DIAGNOSTIC_TEST: CT Perfusion Study|DIAGNOSTIC_TEST: Echocardiogram|DIAGNOSTIC_TEST: neuro-cognitive assessment|DIAGNOSTIC_TEST: MRI
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phase II Study of Adenovirus/PSA Vaccine in Men With Recurrent Prostate Cancer After Local Therapy APP21
Status: COMPLETED
Conditions: Recurrent Prostate Cancer
Interventions: BIOLOGICAL: Adenovirus/PSA Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy Plus Bone Marrow Transplantation in Treating Patients With Refractory Non-Hodgkin's Lymphoma, Hodgkin's Disease, or Multiple Myeloma
Status: COMPLETED
Conditions: Lymphoma|Multiple Myeloma and Plasma Cell Neoplasm
Interventions: BIOLOGICAL: filgrastim|BIOLOGICAL: sargramostim|DRUG: carmustine|DRUG: cyclophosphamide|DRUG: cytarabine|DRUG: etoposide|DRUG: leucovorin calcium|DRUG: methotrexate|DRUG: perfosfamide|DRUG: therapeutic hydrocortisone|PROCEDURE: allogeneic bone marrow transplantation|PROCEDURE: autologous bone marrow transplantation|PROCEDURE: in vitro-treated bone marrow transplantation|PROCEDURE: peripheral blood stem cell transplantation|PROCEDURE: syngeneic bone marrow transplantation|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Nivolumab and RT in Treating Patients With Localized/Locally Advanced Urothelial Bladder Cancer Ineligible for Chemo
Status: COMPLETED
Conditions: Stage II Bladder Urothelial Carcinoma AJCC v6 and v7|Stage III Bladder Urothelial Carcinoma AJCC v6 and v7|Stage IV Bladder Urothelial Carcinoma AJCC v7
Interventions: DRUG: Nivolumab|RADIATION: Radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Gradual Versus Rapid Weight Loss
Status: ACTIVE_NOT_RECRUITING
Conditions: Obesity
Interventions: OTHER: Rapid weight loss (RWL) program|OTHER: Gradual weight loss (GWL) program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Irinotecan or Fluorouracil Plus Leucovorin in Treating Patients With Previously Treated Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: fluorouracil|DRUG: irinotecan hydrochloride|DRUG: leucovorin calcium
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fecal Microbiome Transplantation in Cirrhosis: Trial in Patients With Decompensated Cirrhosis
Status: NOT_YET_RECRUITING
Conditions: Decompensated Cirrhosis
Interventions: DRUG: Fecal Microbiome Transplantation (FMT)|OTHER: FMT Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Ruboxistaurin on Clinically Significant Macular Edema
Status: COMPLETED
Conditions: Diabetic Macular Edema
Interventions: DRUG: Ruboxistaurin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of I-DXd in Combination With Atezolizumab With or Without Carboplatin as First-Line Induction or Maintenance in Subjects With Extensive Stage-Small Cell Lung Cancer (IDeate-Lung03)
Status: RECRUITING
Conditions: Extensive Stage-small Cell Lung Cancer
Interventions: DRUG: Ifinatamab deruxtecan|DRUG: Atezolizumab|DRUG: Carboplatin|DRUG: Etoposide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Risk Factors for PONV in Patients Undergoing Hysteroscopic Surgery
Status: COMPLETED
Conditions: Gynecologic Nursing|Postoperative Complications
Interventions: OTHER: The presence of nausea and vomiting within 24 hours after surgery|OTHER: Non-existence of nausea and vomiting within 24 hours after surgery
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Treatment for Patients With Multiple Hepatocellular Carcinomas Based on the NDR Scoring System
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma
Interventions: PROCEDURE: Hepatectomy|PROCEDURE: TACE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Emergency Front of the NecK Access (eFONA) in Children
Status: COMPLETED
Conditions: Pediatric Anesthesia|Intubation;Difficult
Interventions: OTHER: a rapid sequence tracheostomy (RST) on rabbit cadaver
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effect of Walker vs Wheeled Device on Mobility After Total Knee Arthroplasty
Status: NOT_YET_RECRUITING
Conditions: Total Knee Arthroplasty
Interventions: DEVICE: Mobility Tool
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of n-3 Intake on Lipid Profile, Biochemical and Inflammatory Markers in Subjects With Obesity
Status: COMPLETED
Conditions: Obesity
Interventions: DIETARY_SUPPLEMENT: n-3 supplementation group|DIETARY_SUPPLEMENT: Placebo group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Feasibility Study of Remote Support for Implantable Pulse Generator (IPG)/Implantable Cardioverter Defibrillator (ICD) Implant
Status: COMPLETED
Conditions: Bradycardia|Sudden Cardiac Arrest
Interventions: OTHER: Remote Implant Support Capability
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study Comparing the Effectiveness and Safety of Extended Release Tramadol HCl at 100 mg, 200 mg and 300 mg Doses to Placebo for the Treatment of Moderate to Severe Pain Due to Osteoarthritis (OA)
Status: COMPLETED
Conditions: Chronic Pain
Interventions: DRUG: tramadol HCl ER; celecoxib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Pharmacoeconomic Analysis of First Line Meropenem Versus Standard Antibiotic Treatment in Seriously Infected Secondary Nosocomial Sepsis Syndrome Patients.
Status: COMPLETED
Conditions: Sepsis
Interventions: DRUG: Meropenem
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the PF-06700841 Effect on QTc Interval in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: PF-06700841|DRUG: Placebo|DRUG: moxifloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: AMD3100 Plus Mitoxantrone, Etoposide and Cytarabine in Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Leukemia, Myeloid, Acute
Interventions: DRUG: AMD3100|DRUG: Mitoxantrone|DRUG: Etoposide|DRUG: Cytarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Does Body Mass Index Impact the Outcome of Dural Puncture Epidural in Parturients Undergoing Normal Vaginal Delivery
Status: COMPLETED
Conditions: Morbid Obesity
Interventions: OTHER: Dural puncture epidural
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Erythropoietin on Depressive Symptoms and Neurocognitive Deficits in Depression and Bipolar Disorder
Status: COMPLETED
Conditions: Mood Disorders
Interventions: DRUG: Erythropoietin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Chronic Fatigue Syndrome: A Presumptive Mitochondrial Disorder
Status: WITHDRAWN
Conditions: Chronic Fatigue Syndrome
Interventions: DRUG: Nutraceutical supplements|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Emibetuzumab in Non Small Cell Lung Cancer (NSCLC) Participants
Status: COMPLETED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: Emibetuzumab|DRUG: Erlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Open-label Dose Escalation/Expansion Trial to Evaluate the Safety and Anti-tumor Activity of TEV-56278 Alone or in Combination With Pembrolizumab in Participants With Advanced or Metastatic Solid Tumors
Status: RECRUITING
Conditions: Advanced Solid Tumors
Interventions: DRUG: TEV-56278|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sonidegib and Lenalidomide After Stem Cell Transplant in Treating Patients With Multiple Myeloma
Status: COMPLETED
Conditions: Recurrent Plasma Cell Myeloma|Refractory Plasma Cell Myeloma
Interventions: OTHER: Laboratory Biomarker Analysis|DRUG: Lenalidomide|DRUG: Sonidegib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Long-term, Continued Treatment and Follow-up Study in Participants With Hematologic Malignancies Treated With Duvelisib (IPI-145)
Status: COMPLETED
Conditions: Hematologic Malignancy
Interventions: DRUG: Duvelisib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Using Micronised Progesterone (Crinone® 8%) in the Luteal Phase Support of Women Undergoing in Vitro Fertilisation (IVF) and Embryo Transfer (ET)
Status: COMPLETED
Conditions: Infertility
Interventions: DRUG: Micronised Progesterone|DRUG: Progesterone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare Two Different Subcutaneously-administered JNJ-64304500 Formulations in Healthy Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: JNJ 64304500|DRUG: JNJ 64304500
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sequential Chemo-immunotherapy Plus Thoracic Radiotherapy for Elderly and/or Frail Stage III Non-small-cell Lung Cancer
Status: RECRUITING
Conditions: Non-small Cell Lung Cancer Stage III
Interventions: RADIATION: standar thoracic RT dose|RADIATION: decreased thoracic RT dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Probucol for Symptomatic Intracranial and Extracranial Artery Stenosis
Status: RECRUITING
Conditions: Ischemic Stroke|TIA
Interventions: DRUG: Probucol|DRUG: Placebo probucol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Electric Massage on the Cervical Region in Subjects Diagnosed With Temporomandibular Disorders
Status: COMPLETED
Conditions: Temporomandibular Disorders
Interventions: OTHER: Group 1: Manual Therapy|OTHER: Group 2: Interferential massage plus Manual Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Qlaris Study of QLS-111 in Combination With a PGA for OAG and/or OHT Patients
Status: RECRUITING
Conditions: Open-angle Glaucoma (OAG)|Ocular Hypertension (OHT)|Glaucoma
Interventions: DRUG: QLS-111, 0.015%|DRUG: QLS-111, 0.030%|DRUG: QLS-111, 0.075%|DRUG: QLS-111 vehicle ophthalmic solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Upper Extremity Rehabilitation Using Immersive Virtual Reality in Chronic Stroke Patients.
Status: RECRUITING
Conditions: Stroke
Interventions: DEVICE: Virtual reality exergames|BEHAVIORAL: Conventional occupational therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Thiosulfate Enhanced Organ Preservation Solution in Kidney Transplantation
Status: NOT_YET_RECRUITING
Conditions: Renal Transplant|Kidney Transplant
Interventions: DRUG: Sodium Thiosulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Gravity- Versus Suction-driven Large Volume Thoracentesis
Status: COMPLETED
Conditions: Pleural Effusion
Interventions: PROCEDURE: Suction-Driven Thoracentesis|PROCEDURE: Gravity-Driven Thoracentesis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of an Artificial Tear for the Treatment of Dry Eye
Status: COMPLETED
Conditions: Dry Eye Syndrome
Interventions: DRUG: Carboxymethylcellulose and Glycerin based artificial tear|DRUG: Carboxymethylcellulose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Adjuvant Continuous Infusion of Nefopam Versus Standard of Care in Mechanically Ventilated Critically Ill Patients: Randomized Double-blind Controlled Study
Status: RECRUITING
Conditions: Analgesia|Critical Illness|Mechanical Ventilation|Sedation
Interventions: DRUG: Nefopam|DRUG: Standard of care in the ICU for assessment and management of pain, sedation, and delirium.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate The Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of JZP441 in Sleep-deprived Healthy Participants
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DRUG: JZP441|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Rasagiline Rescue in Alzheimer's Disease Clinical Trial
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: Rasagiline|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Hematopoietic Stem Cell Transplant Survivors Study
Status: RECRUITING
Conditions: Stem Cell Transplant
Interventions: OTHER: Standard of Care - Observation Only|DRUG: Group 2: Quercetin|DRUG: Group 2: Dasatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Double-blind, Randomised Study to Assess the Influence of Tiotropium (Spiriva®)
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: tiotropium 18 mcg or 54 mcg qd|DRUG: placebo matching tiotropium qd|DRUG: moxifloxacin 200 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Drug Use Surveillance of Vonoprazan for "Gastric Ulcer, Duodenal Ulcer, and Reflux Esophagitis"
Status: COMPLETED
Conditions: Gastric Ulcer, Duodenal Ulcer, and Reflux Esophagitis
Interventions: DRUG: Vonoprazan
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Hepatectomy Versus Hepatectomy With Lymphadenectomy in Hepatocellular Carcinoma
Status: COMPLETED
Conditions: Hepatocellular Carcinoma
Interventions: PROCEDURE: hepatectomy combined with lymphadenectomy|PROCEDURE: hepatectomy alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Enhancing Self-Efficacy for Caregivers of Family Members With Spinal Cord Injury
Status: COMPLETED
Conditions: Spinal Cord Injury
Interventions: BEHAVIORAL: Reinvention Protocol Participants|BEHAVIORAL: Wait List
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1/2 Trial of ARV-471 Alone and in Combination With Palbociclib (IBRANCE®) in Patients With ER+/HER2- Locally Advanced or Metastatic Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: ARV-471|DRUG: ARV-471 in combination with palbociclib (IBRANCE®)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MINDSpeed Food and Brain Training RCT
Status: COMPLETED
Conditions: Low Education|Cognition|Cognitive Training|Polyphenols
Interventions: BEHAVIORAL: Speed of processing training|BEHAVIORAL: MIND foods|BEHAVIORAL: Cognitive training control|BEHAVIORAL: Control foods
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of Genetic and Environmental Factors and Their Effect on Response to Treatment With Lucentis (Ranibizumab) for Wet AMD
Status: COMPLETED
Conditions: Macular Degeneration
Interventions: DRUG: Ranibizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Two Therapies for the Treatment of Osteoarticular Inflammation in Dyspeptic Patients
Status: COMPLETED
Conditions: Acute and Chronic Inflammation|Dyspepsia
Interventions: DRUG: Nimesulide + Pantoprazole|DRUG: Naproxen + Esomeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Minimal Opioid Use After Total Hip Replacement (THR)
Status: COMPLETED
Conditions: Osteoarthritis, Hip
Interventions: PROCEDURE: Periarticular injection (Deep injection)|PROCEDURE: Periarticular injection (Superficial injection)|DRUG: Bupivacaine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Suboccipital Release Technique in Individuals With Anxiety
Status: COMPLETED
Conditions: Anxiety|Trapezius Muscle Strain|Pain
Interventions: OTHER: Suboccipital Release Technique|OTHER: Sham Suboccipital Release
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: AMG 176 First in Human Trial in Participants With Relapsed or Refractory Multiple Myeloma and Participants With Relapsed or Refractory Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Relapsed or Refractory Multiple Myeloma|Relapsed or Refractory Acute Myeloid Leukemia
Interventions: DRUG: AMG 176|DRUG: Azacitidine|DRUG: Itraconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Open-label, Bridging Study of BARYCELA Inj. in Healthy Vietnamese Children Aged Between 12 Months to 12 Years
Status: NOT_YET_RECRUITING
Conditions: Varicella Zoster Virus Infection
Interventions: BIOLOGICAL: MG1111
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: An Internet Delivered Intervention for Re-Adjustment to Sexual Intimacy With an Ostomy After Cancer
Status: UNKNOWN
Conditions: Colorectal Cancer|Sexual Dysfunction
Interventions: OTHER: Internet-Delivered Intervention for Sexual Re-Adjustment|OTHER: Written Educational Material
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: This Study Tests the Effect of Certain Medicines on the Transport of Other Medicines in the Body of Healthy Men
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Digoxin|DRUG: Furosemide|DRUG: Metformin|DRUG: Rosuvastatin|DRUG: Verapamil|DRUG: Rifampin|DRUG: Cimetidine|DRUG: Probenecid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Evaluation of the Gastric Tube Guide to Place Orogastric Tubes
Status: COMPLETED
Conditions: Orogastric Tube Placement
Interventions: DEVICE: Gastric Tube Guide|DEVICE: Conventional placement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: HYPAZ: Hypertension Induced by Pazopanib
Status: TERMINATED
Conditions: Renal Cell Carcinoma|Soft Tissue Sarcoma|Glioblastoma|Ovarian Cancer|Cervical Cancer|Breast Cancer|Non-small Cell Lung Cancer|Small Cell Lung Cancer|Pancreatic Cancer|Melanoma|Gastrointestinal Cancer
Interventions: DRUG: Pazopanib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Calcium- D Supplement on Hypertension
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Calcium D|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Determining the Safe Dosage of Ascorbic Acid Used in the Treatment of Occluded Totally Implanted Central Venous Catheter
Status: COMPLETED
Conditions: Occluded Totally Implanted Central Venous Catheter
Interventions: DRUG: Ascorbic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Pharmacokinetics, Safety and Efficacy of P03277 in Pediatric Patients Undergoing Central Nervous System Contrast-enhanced MRI
Status: COMPLETED
Conditions: Central Nervous System Indication|Pediatric Patients|Body Indication
Interventions: DRUG: P03277
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Polysomnographic Study Of Single-Dose Gabapentin In Transient Insomnia
Status: COMPLETED
Conditions: Transient Insomnia
Interventions: DRUG: Gabapentin|DRUG: Gabapentin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT