pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Combination Chemotherapy With or Without Hypofractionated Radiation Therapy Before Surgery in Treating Patients With Pancreatic Cancer
Status: UNKNOWN
Conditions: Pancreatic Adenocarcinoma|Borderline Resectable Adenocarcinoma of the Head of the Pancrease
Interventions: RADIATION: radiation therapy|PROCEDURE: surgery|DRUG: mFOLFIRINOX|DRUG: FOLFOX
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasound-Guided Injections for Meniscal Injuries in Active-Duty Military
Status: RECRUITING
Conditions: Tibial Meniscus Injuries|Knee Injuries|Knee Injuries and Disorders
Interventions: DEVICE: Lipogems|DRUG: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Ovarian Reserve in Patients Who Hypogastric Arteries and or Uterine Arteries Had Been Ligated
Status: UNKNOWN
Conditions: Ovarian Reserve|Hypogastric Artery Ligation|Uterine Artery Ligation
Interventions: PROCEDURE: Hypogastric and/or uterine artery ligation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study Evaluating 24-Week and 48-Week Telaprevir-Based Regimen in Treatment Naïve Subjects With Genotype 1 Chronic Hepatitis C Who Achieve an Extended Rapid Viral Response
Status: COMPLETED
Conditions: Hepatitis C
Interventions: DRUG: telaprevir|DRUG: ribavirin|BIOLOGICAL: peginterferon alfa-2a
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: W0261-101: A Phase 1, Single Center, Randomized, Open-Label Study to Evaluate the Bioavailability of Clindamycin From Clindamycin 1%-Benzoyl Peroxide 3% Gel, Topical Gel (Clindamycin 1%- Benzoyl Peroxide 5%), and Once Daily Gel (Clindamycin 1%-Benzoyl Peroxide 5%) in Subjects With Acne
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: Clindamycin 1%-Benzoyl Peroxide (BPO) 3% Gel,
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PH III Study of Lenalidomide and Dexamethasone With or Without Elotuzumab to Treat Previously Untreated Multiple Myeloma (ELO 1 Substudy)
Status: TERMINATED
Conditions: Newly Diagnosed, Previously Untreated Multiple Myeloma
Interventions: DRUG: Lenalidomide|DRUG: Dexamethasone|BIOLOGICAL: Elotuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Serum Cholesterol Reduction Efficacy of Biscuit With Plant Stanol Ester
Status: COMPLETED
Conditions: Dyslipidemias|Hypercholesterolemia|Hyperlipidemias
Interventions: DIETARY_SUPPLEMENT: Plant stanol ester|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Functional Assessment of a Vibration Feedback on the Gripping Pressure in the Territory of the Median Nerve
Status: TERMINATED
Conditions: Sensory Deficit
Interventions: PROCEDURE: pressure sensor and wrist shaker, not marked CE, developped by Texisense
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Clinical Study in Healthy Subjects to Evaluate 9MW1911 Injection
Status: COMPLETED
Conditions: Asthma|COPD|Atopic Dermatitis
Interventions: DRUG: 9MW1911 Injection|DRUG: 9MW1911 Injection Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intergenerational Program for Social Isolation and Loneliness in Older Adults Discharged From the Emergency Department
Status: RECRUITING
Conditions: Social Isolation|Loneliness|Geriatric
Interventions: BEHAVIORAL: Intergenerational HOW R U?|BEHAVIORAL: Same-Generation Peer Support HOW R U?
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of the Efficacy and Tolerance of a Light Therapy Mask on Mild to Moderate Brown Spots and Moderate to Severe Facial Wrinkles
Status: COMPLETED
Conditions: Skin Aging
Interventions: DEVICE: Active Mask|DEVICE: Sham Mask
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acute Achilles Repair With or Without OrthADAPT Augmentation
Status: WITHDRAWN
Conditions: Achilles Tendon Tear
Interventions: DEVICE: Achilles repair with OrthADAPT augmentation|PROCEDURE: Achilles repair without OrthADAPT Augmentation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy & Safety of TD-1473 in Ulcerative Colitis
Status: TERMINATED
Conditions: Ulcerative Colitis (UC)
Interventions: DRUG: TD-1473 Dose A|DRUG: TD-1473 Dose B|DRUG: TD-1473 Dose C|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of the Liquid Embolic System (Tonbridge) for Endovascular Treatment of Cerebrovascular Malformations
Status: NOT_YET_RECRUITING
Conditions: Intracranial Arteriovenous Malformations
Interventions: DEVICE: Liquid Embolic System (Tonbridge)|DEVICE: Onyx Liquid Embolic System (Medtronic)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Walnut Consumption on Endothelial Function in Type 2 Diabetes
Status: COMPLETED
Conditions: DIABETES MELLITUS TYPE 2
Interventions: DIETARY_SUPPLEMENT: Walnut supplementation|DIETARY_SUPPLEMENT: Ad lib diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Point-of-Care Ultrasonography for Intussusception
Status: COMPLETED
Conditions: Intussusception|Emergencies
Interventions: DIAGNOSTIC_TEST: Point-of-care ultrasound prior to radiology ultrasound|DIAGNOSTIC_TEST: Radiology-performed ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Bifidobacterium Animalis Subsp. Lactis HN019 on Oral Lichen Planus
Status: COMPLETED
Conditions: Oral Lichen Planus
Interventions: DRUG: Bifidobacterium animalis subsp. lactis HN019|DRUG: Clobetasol propionate 0.05%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Hemodynamically Important Patent Ductus Arteriosus in Newborns Under 32 Weeks
Status: RECRUITING
Conditions: Patent Ductus Arteriosus After Premature Birth
Interventions: DIAGNOSTIC_TEST: Echocardiography, Doppler ultrasonography, Near-infrared spectroscopy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Evaluate the Pharmacokinetics and Safety Between HCP2202 and Co-administration of Each Component in Healthy Volunteers Under Fed Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: HCP2202|DRUG: RLD2202|DRUG: RLD2203
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Disgust and Shame Based Safe Water and Handwashing Promotion
Status: COMPLETED
Conditions: Develop a New Group Version of the Becker-DeGroot-Marsckek (BDM) Auction to Measure Willingness to Pay of Compound Members for Shared Hardware.|Develop a New Survey Instrument to Measure Behavioural Determinants of Hand Washing and Water Treatment Like Disgust and Shame or Social Pressure.|Identify New Methods for Measuring Hand Washing and Water Treatment Behaviour.|Compare the Effectiveness of the Disgust and Shame Based Interventions With Standard Public Health Interventions.
Interventions: BEHAVIORAL: Standard Public Health Intervention with Water Treatment|BEHAVIORAL: Standard Public Health Intervention with Water Treatment & Hand Washing|BEHAVIORAL: Disgust and Shame Based Intervention with Water Treatment|BEHAVIORAL: Disgust and Shame Based Intervention with Water Treatment & Hand Washing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: pBFS Guided rTMS Treating Mild Alzheimer's Disease(AD)
Status: RECRUITING
Conditions: Mild Alzheimer's Disease
Interventions: DEVICE: active rTMS|DEVICE: sham rTMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Terazosin and Tolterodine on Ureteral Stent Related Symptoms
Status: COMPLETED
Conditions: Disorder of Urinary Stent
Interventions: DRUG: Placebo|DRUG: Terazosine|DRUG: Tolterodine|DRUG: Tolterodine + Terazosin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study of SHR-1314 Injection in the Treatment of Moderate to Severe Plaque Psoriasis in Adults
Status: SUSPENDED
Conditions: Plaque Psoriasis
Interventions: BIOLOGICAL: IL-17A Antagonist|BIOLOGICAL: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trans-Pacific Multicenter Collaborative Study of Minimally Invasive Proximal Versus Total Gastrectomy for Proximal Gastric and Gastroesophageal Junction Cancers
Status: RECRUITING
Conditions: Gastrostomy|Gastric|GastroEsophageal Cancer
Interventions: OTHER: Standard of Care|OTHER: Control Group
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Suppressive Antibacterial Therapy With Once-Weekly Secnidazole Granules to Prevent Recurrent Bacterial Vaginosis; A Pilot Study
Status: COMPLETED
Conditions: Recurrent Bacterial Vaginosis
Interventions: DRUG: Secnidazole 2 GM Oral Granules
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Decentralized N=1 Study: A Feasible Approach to Evaluate Individual Therapy Response to Dapagliflozin.
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Diabetes Mellitus Type 2 With Proteinuria|Diabetes Mellitus|Diabetes|Diabetes Complications|Albuminuria|Chronic Kidney Diseases|Chronic Kidney Disease Due to Type 2 Diabetes Mellitus|CKD|Proteinuria
Interventions: DRUG: Dapagliflozin 10mg Tab|DRUG: Placebo|DEVICE: Withings BPM Connect|DEVICE: Withings Body+|DIAGNOSTIC_TEST: Hem-Col Capillary Blood Collection Device|DEVICE: MEMS (Medication Electronic Monitoring System) Cap|BEHAVIORAL: Questionnaire: participants' perspectives toward remote data collection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Transplantation of Hematopoietic Progenitors From Haploidentical Donor With Selective in Vitro Depletion Allo-reactive Lymphocytes in Patient With High Risk Hematological Malignancies
Status: WITHDRAWN
Conditions: Transplant-Related Hematologic Malignancy
Interventions: OTHER: Allo-depleted lymphocyte infusion|OTHER: Haploidentical transplantation of hematopoietic progenitors
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Desensitization Therapy in Sensitized Participants Awaiting Heart Transplantation
Status: TERMINATED
Conditions: Primary Heart Transplant|Heart Transplantation|Heart Transplant
Interventions: DRUG: bortezomib|PROCEDURE: plasmapheresis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Exploring the Safety, Tolerability and Efficacy of a 4 Week Course of INCB018424 in Subjects With Active Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: INCB018424|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: NAN-101 in Patients With Class III Heart Failure
Status: RECRUITING
Conditions: Congestive Heart Failure|Heart Failure|Heart Disease, Ischemic|Cardiovascular Diseases|Heart Failure, Systolic|Heart Failure，Congestive|Heart Arrhythmia|Heart Failure, Diastolic|Heart; Complications
Interventions: BIOLOGICAL: 3 x 10e13vg NAN-101
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Severe Limb Ischemia With Autologous Bonemarrow Derived Mononuclear Cells
Status: UNKNOWN
Conditions: Ischemia
Interventions: PROCEDURE: Stem cell implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Proof-of-Concept Study to Correlate Retinal Nerve Fiber Layer Changes in Patients With Multiple Sclerosis Treated With Natalizumab or Interferon Beta 1-a
Status: WITHDRAWN
Conditions: Relapsing-remitting Multiple Sclerosis
Interventions: DRUG: TYSABRI and AVONEX
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Rectal Indomethacin in Prevention of Post-operative Pancreatitis After Pancreaticoduodenectomy
Status: COMPLETED
Conditions: Pancreatoduodenectomy
Interventions: DRUG: Indomethacin suppository|OTHER: Standard Medical Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluate the Efficacy and Safety of DWJ1506 and DWJ1507
Status: UNKNOWN
Conditions: Dyslipidemias
Interventions: DRUG: DWJ1506|DRUG: DWJ1507|DRUG: DWC202011|DRUG: DWJ1177
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Primary carE PPi dEprescRibing Trial
Status: RECRUITING
Conditions: Heartburn|Dyspepsia|Reflux
Interventions: PROCEDURE: de-prescription of PPI via intermittent scheme|PROCEDURE: de-prescription of PPI via on-demand scheme|DRUG: Alginate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Kinesio Taping on Muscle Strength in Quadriceps Femoris
Status: COMPLETED
Conditions: Anterior Knee Pain|Muscle Weakness|Knee Symptoms
Interventions: OTHER: Kinesio tape
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluatioon of 177Lu-TATE-EB-01（LNC1010）in SSTR2-positive Tumors
Status: RECRUITING
Conditions: SSTR2-positive Tumors
Interventions: DRUG: 177Lu-LNC1010 1|DRUG: 177Lu-LNC1010 2|DRUG: 177Lu-LNC1010 3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Microdosing Psychedelics to Improve Mood
Status: RECRUITING
Conditions: Major Depressive Disorder
Interventions: DRUG: Psilocybin first|DRUG: Placebo first
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: AMP-BPT and His-BPT for Assessment of Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: inhaled corticosteroids (usually budesonide/fomorterol 160/4.5mcg; fluticasone/salmeterol 250/50mcg)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Multimodal Approach in Patients With mHSPC. Randomized Trial of APA+ADT vs APA-ADT and Local Treatment
Status: RECRUITING
Conditions: Metastatic Hormone-Sensitive Prostate Cancer (mHSPC)
Interventions: DRUG: APA + ADT|PROCEDURE: Local Treatmetn RT or RP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hepatic Glycogen and Fat Oxidation
Status: COMPLETED
Conditions: Fatty Liver, Nonalcoholic|Meal Time|Fasting|Glycogen Depletion
Interventions: BEHAVIORAL: Overnight fasting duration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Sequencing Antibody Drug Conjugates in ER+/HER2 LOW MBC
Status: RECRUITING
Conditions: Breast Cancer|Metastatic Breast Cancer|Advanced Breast Cancer|Hormone-receptor-positive Breast Cancer|Human Epidermal Growth Factor 2 Low Breast Cancer
Interventions: DRUG: Sacituzumab govitecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Progesterone on Latent Phase Prolongation in Patients With Preterm Premature Rupture of Membranes
Status: COMPLETED
Conditions: Preterm Premature Rupture of Membrane
Interventions: DRUG: 17-hydroxyprogesterone caproate|DRUG: Castor Oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: BOAT: Beta Blocker Uptitration With OptiVol After Cardiac Resynchronization Therapy (CRT)
Status: TERMINATED
Conditions: Congestive Heart Failure
Interventions: DRUG: Beta blocker (carvedilol or metoprolol succinate)|PROCEDURE: CRT (cardiac resynchronization therapy)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Apatinib for Resectable Colorectal Cancer
Status: WITHDRAWN
Conditions: Apatinib|Outcome, Fatal|Colorectal Cancer|Surgery|Adjuvant Chemotherapy
Interventions: DRUG: Apatinib|DRUG: CAPEOX
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating the Bioavailability of Naproxen 500 mg in Three Formulations
Status: COMPLETED
Conditions: Arthritis
Interventions: DRUG: PN400|DRUG: naproxen|DRUG: naproxen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Phase 3 Study of Zalunfiban in Subjects With ST-elevation MI
Status: RECRUITING
Conditions: ST-elevation Myocardial Infarction (STEMI)
Interventions: DRUG: zalunfiban|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: T Cells Expressing a Fully-human AntiCD19 Chimeric Antigen Receptor for Treating B-cell Malignancies
Status: COMPLETED
Conditions: Lymphoma, B-Cell|Lymphoma, Non-hodgkins
Interventions: BIOLOGICAL: Anti-cluster of differentiation 19 (CD19)-Chimeric Antigen Receptor (CAR) T cells|DRUG: Cyclophosphamide|DRUG: Fludarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Auditory-somatosensory Stimulation to Alleviate Tinnitus
Status: COMPLETED
Conditions: Tinnitus
Interventions: DEVICE: Sham Treatment: unimodal auditory stimulation|DEVICE: Active Treatment: Bimodal auditory-somatosensory stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility of Primer Shot Radiotherapy for Non-small Cell Lung Cancer - PRIMER
Status: NOT_YET_RECRUITING
Conditions: Patients With NSCLC Stage 2-4
Interventions: RADIATION: RT (5x6 Gy) to the primary tumor and, if indicated, to lymph node and/or distant metastases.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sumatriptan 4 mg Statdose in the Acute Treatment of Cluster Headache
Status: UNKNOWN
Conditions: Episodic Cluster Headache|Chronic Cluster Headache
Interventions: DRUG: Sumatriptan 4mg Statdose injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Evaluate the Safety and Efficacy of IM21 CAR-T Cells in Patients With Relapsed and Refractory (R/R) Multiple Myeloma
Status: UNKNOWN
Conditions: Multiple Myeloma
Interventions: BIOLOGICAL: IM21 CAR-T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Autologous Stem Cells Transplantation in Patients With Idiopathic and Drug Induced Premature Ovarian Failure
Status: UNKNOWN
Conditions: Premature Ovarian Failure
Interventions: BIOLOGICAL: Biological: Stem Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: the Effect of Broken Ganoderma Lucidum Spore Powder on Quality of Life and Immune Function in Patients With Diffuse Large B-cell Lymphoma After Chemotherapy
Status: UNKNOWN
Conditions: Diffuse Large B-cell Lymphoma
Interventions: OTHER: broken Ganoderma lucidum spore powder|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cranio- Cervical Flexion Training With and Without Pressure Biofeedback in Mechanical Neck Pain
Status: COMPLETED
Conditions: Mechanical Neck Pain
Interventions: DEVICE: Craniocervical flexion training with pressure biofeedback|OTHER: Craniocervical flexion training without pressure biofeedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Impact of Chyme Reinfusion Compared to Parenteral Nutrition on the Incidence of Complications in Patients With a Temporary High-output Double Enterostomy: a Multicentre Randomized Controlled Trial - FRY: efFiciency of Reinfusion of chYme - (FRY)
Status: UNKNOWN
Conditions: Intestinal Failure With a Temporary High-output Double Enterostomy
Interventions: DEVICE: Entéromate™|DRUG: parenteral nutrition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase II Trial of TPF Induction Chemotherapy in cN2 OSCC Patients
Status: TERMINATED
Conditions: Mouth Neoplasms|Carcinoma, Squamous Cell
Interventions: DRUG: TPF induction chemotherapy|PROCEDURE: surgery|RADIATION: radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Local Glucocorticoids for the Treatment of Acute Radiation-Induced Intestinal Injury
Status: RECRUITING
Conditions: Radiation-Induced Intestinal Injury
Interventions: DRUG: Dexamethasone|DRUG: Antibiotics, probiotics, vitamins, antidiarrheal drugs, enteral nutrition, and endoscopic argon plasma coagulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: mLab App Plus: A Randomized Controlled Trial of a Mobile Health (mHealth) Intervention
Status: RECRUITING
Conditions: HIV Infections|Sexually Transmitted Diseases, Viral|Syphilis
Interventions: BEHAVIORAL: mLab App Plus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy and Safety of Volinanserin on Sleep Maintenance Insomnia - Polysomnographic Study
Status: COMPLETED
Conditions: Sleep Initiation and Maintenance Disorders
Interventions: DRUG: volinanserin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Lidocaine Infusion as a Treatment for Cocaine Relapse and Craving
Status: COMPLETED
Conditions: Cocaine Addiction
Interventions: DRUG: lidocaine following cue-induced craving|DRUG: lidocaine following neutral stimulus|DRUG: saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Comparing Tan EndoGlide With the Busin Glide for Insertion of the Donor Graft in DSAEK
Status: UNKNOWN
Conditions: Endothelial Cell Loss With Different Insertion Devices
Interventions: DEVICE: Use of the Tan EndoGlide to insert donor graft|DEVICE: Busin Glide for delivery of the donor graft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Treatment With Olverembatinib in CML-CP Patients Who Failed to at Least Two Previously Administered Second-generation TKIs.
Status: RECRUITING
Conditions: Olverembatinib|Chronic Myeloid Leukemia, Chronic Phase|Tyrosine Kinase Inhibitors
Interventions: DRUG: olverembatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of PD-L1 Antibody KN035 in Japanese Subjects With Locally Advanced or Metastatic Solid Tumors
Status: COMPLETED
Conditions: Advanced or Metastatic Solid Tumors
Interventions: DRUG: KN035
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacological Treatment In Osteoarthritis
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DRUG: Hydroxychloroquine|DRUG: cellulose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Myofascial Release in Patients With Chronic Obstructive Pulmonary Disease
Status: NOT_YET_RECRUITING
Conditions: Copd
Interventions: OTHER: Experimental-Myofascial + Respiratory rehabilitation|OTHER: Sham Myofascial + Respiratory rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hyaluronic Acid Versus Red Injectable Platelet Rich Fibrin in Treatment of Periodontitis
Status: COMPLETED
Conditions: Periodontitis Chronic Generalized Severe
Interventions: DRUG: Hyaluronic acid|PROCEDURE: red injectable platelet rich fibrin (i-prf)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of tDCS on Motor Performance and Cortical Excitability
Status: COMPLETED
Conditions: Cortical Excitability|Motor Performance|tDCS
Interventions: DEVICE: transcranial direct current stimulation (tDCS) (NeuroConn DC-stimulator)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety of Flunotinib Maleate Tablets for the Treatment of Patients With Myeloproliferative
Status: RECRUITING
Conditions: Myeloproliferative Neoplasm (MPN)|Myelofibrosis，MF
Interventions: DRUG: flonoltinib 25mg|DRUG: flonoltinib 50mg|DRUG: flonoltinib 100mg|DRUG: flonoltinib 150mg|DRUG: flonoltinib 225mg|DRUG: flonoltinib 325mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Carboplatin, Gemcitabine Hydrochloride, and Berzosertib in Treating Patients With Recurrent and Metastatic Ovarian, Primary Peritoneal, or Fallopian Tube Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Fallopian Tube Carcinoma|Metastatic Ovarian Carcinoma|Metastatic Primary Peritoneal Carcinoma|Ovarian Endometrioid Tumor|Ovarian High Grade Serous Adenocarcinoma|Platinum-Sensitive Ovarian Carcinoma|Recurrent Fallopian Tube Carcinoma|Recurrent Ovarian Carcinoma|Recurrent Primary Peritoneal Carcinoma|Stage IV Fallopian Tube Cancer AJCC v6 and v7|Stage IV Ovarian Cancer AJCC v6 and v7|Stage IV Primary Peritoneal Cancer AJCC v7
Interventions: DRUG: Berzosertib|DRUG: Carboplatin|DRUG: Gemcitabine Hydrochloride|OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacological Study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Minimally Invasive Treatment of Primary Great Saphenous Vein (GSV) Insufficiency Using High Intensity Focused Ultrasound (HIFU)
Status: COMPLETED
Conditions: Great Saphenous Vein Insufficiency
Interventions: DEVICE: Sonovein Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Spine Biomechanics During Gait Following Lower Extremity Treatment in Different Patient Groups
Status: COMPLETED
Conditions: Leg Length Inequality|Cerebral Palsy
Interventions: OTHER: Ankle foot orthosis|OTHER: Shoe insole|OTHER: Modified shoe with sole lift
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: the Efficacy and Safety of Sugammadex in Children 0-2 Years Old
Status: UNKNOWN
Conditions: Anesthesia|Pediatric Cancer|Pediatric Tumor|Pediatric Hepatoblastoma|Beta-Thalassemia|Hepatic Metastases
Interventions: DRUG: Sugammadex
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevention of Cervical Cancer Through an HPV-based Screen-and-treat Strategy in Malawi
Status: COMPLETED
Conditions: Cervical Cancer
Interventions: OTHER: Community-based HPV screening strategy|OTHER: Clinic-based HPV screening strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Preoperative Corticosteroid Therapy in Neonates Undergoing Cardiopulmonary Bypass
Status: COMPLETED
Conditions: Congenital Heart Disease|Disorder of Fetus or Newborn
Interventions: DRUG: methylprednisolone (IVMP)|DRUG: methylprednisolone (two doses IVMP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Impact of Perioperative Gabapentin on Chronic Groin Pain After Inguinal Hernia Repair
Status: UNKNOWN
Conditions: Peripheral Nerve Disorder Associated With Repair of Hernia
Interventions: DRUG: Gabapentin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Human Myeloid Progenitor Cells (CLT-008) After Chemotherapy for Leukemia
Status: COMPLETED
Conditions: Acute Myeloid Leukemia|Acute Lymphoblastic Leukemia|Chronic Myeloid Leukemia|Myelodysplasia
Interventions: BIOLOGICAL: human myeloid progenitor cells|DRUG: G-CSF
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Cutaneous Prostaglandin Application: Nail Growth, Nail Brittleness, and Eye Pressure
Status: COMPLETED
Conditions: Nail Growth Cessation|Intraocular Pressure
Interventions: DRUG: Bimatoprost 0.01%|OTHER: Placebo: saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Comparing Two Populations of Patients Treated With Anti VEGF for Diabetic Macular Edema, One Being Followed at the Hospital and the Other One Being Followed at Home Using a Software Allowing Self-assessment of Visual Acuity
Status: UNKNOWN
Conditions: Diabetic Macular Edema
Interventions: OTHER: telemedecine follow-up
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Continuous Labor Epidural Catheter for Tubal Ligation Study
Status: TERMINATED
Conditions: Tubal Ligation|Bilateral Tubal Ligation
Interventions: OTHER: Epidural anesthetic|OTHER: Spinal anesthetic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Impact of Energy Drinks on the Manual Dexterity of Final Year Dental Students
Status: COMPLETED
Conditions: Hand Skill, Relative
Interventions: OTHER: Test Cavity Preparation|DRUG: Taurine|OTHER: Post intervention test cavity|DIETARY_SUPPLEMENT: Carbonated Apple Juice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Prospective Trial for Endoscopic Ultrasound Guided Gallbladder Drainage for Acute Cholecystitis in High Risk Patients
Status: COMPLETED
Conditions: Cholecystitis
Interventions: PROCEDURE: EUS-guided gallbladder drainage|PROCEDURE: percutaneous transhepatic gallbladder drainage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Thymosin Alpha 1, Interferon Alpha, or Both, in Combination With Dacarbazine in Patients With Malignant Melanoma
Status: COMPLETED
Conditions: Malignant Melanoma
Interventions: BIOLOGICAL: Dacarbazine + Interferon alpha + Thymosin-alpha-1 1.6 mg|BIOLOGICAL: Dacarbazine + Interferon alpha + Thymosin-alpha-1 3.2 mg|BIOLOGICAL: Dacarbazine + Interferon alpha + Thymosin-alpha-1 6.4 mg|BIOLOGICAL: Dacarbazine + Thymosin-alpha-1 3.2 mg|DRUG: Dacarbazine + Interferon alpha
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exploit the Functional Higher Neural Connectivity and Electrophysiological Intervention of Freezing of Gait in PD and PSP During Different Ambulatory Complexities
Status: UNKNOWN
Conditions: Transcranial Direct Current Stimulation
Interventions: DEVICE: Transcranial direct current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Early Menopause Hormone Treatment and Cognition
Status: COMPLETED
Conditions: Menopausal Syndrome
Interventions: DRUG: Estradiol (E2)|DRUG: Progesterone (P10) x90|DRUG: Progesterone (P10) x10
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Topotecan and Thalidomide in Treating Patients With Recurrent or Refractory Malignant Glioma
Status: TERMINATED
Conditions: Brain and Central Nervous System Tumors
Interventions: DRUG: thalidomide|DRUG: topotecan hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Testing of Collagen Peptide Drink
Status: COMPLETED
Conditions: Skin Condition
Interventions: DIETARY_SUPPLEMENT: Collagen Peptide Drink|DIETARY_SUPPLEMENT: Placebo drink
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Photodynamic Therapy Incubation Times for Actinic Keratosis
Status: ACTIVE_NOT_RECRUITING
Conditions: Actinic Keratoses
Interventions: DRUG: ALA (5-aminolevulinic acid)|DEVICE: Blue light therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PLD Combined With Cisplatin in the Treatment of Advanced Poorly Differentiated Thyroid Carcinoma
Status: UNKNOWN
Conditions: Poorly Differentiated Thyroid Carcinoma
Interventions: DRUG: PLD|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Applied Study on the Use of Stone Needles Therapy to Assist the Rehabilitation of Maternal Diastasis Rectus Abdominis Based on the Theory of Belt Channel
Status: RECRUITING
Conditions: Diastasis Recti Abdominis
Interventions: OTHER: Stone needle therapy follows the Belt channel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dapsone 100 Mg Versus 50 as Primary Prophylaxis for Pneumocystis Carinii Pneumonia (PCP) in Patients With AIDS-Related Complex (ARC)
Status: COMPLETED
Conditions: Pneumonia, Pneumocystis Carinii|HIV Infections
Interventions: DRUG: Dapsone
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Comparative Analysis of Spinal Anesthesia Versus General Anesthesia for vNOTES
Status: ENROLLING_BY_INVITATION
Conditions: Anesthesia|Tubal Ligation
Interventions: PROCEDURE: Spinal Anesthesia|PROCEDURE: General Anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Clinical Trial of West-China Perioperative Transfusion Score (WCPTS）for Massive Hemorrhagic Surgery
Status: COMPLETED
Conditions: Transfusion Related Complications
Interventions: OTHER: Maintenance of hemoglobin level not less than 10g/dL|OTHER: Transfusion trigger based on WCPTS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Remote Ischemic Conditioning in Abdominal Surgery
Status: UNKNOWN
Conditions: Laparotomy|Laparoscopy|Retroperitoneal Disease|Pelvis Disease|Pancreatic Diseases|Liver Diseases|Gastrointestinal Disease|Urologic Diseases|Complication of Surgical Procedure
Interventions: PROCEDURE: Remote ischemic conditioning|PROCEDURE: No Remote ischemic conditioning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Diclofenac Suppository for Pain Control in Ultrasound Guided Biopsy of Prostate
Status: COMPLETED
Conditions: Carcinoma Prostate
Interventions: DRUG: Diclofenac suppository plus lidocaine gel|DRUG: Lidocaine gel only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Fruit and Vegetable Concentrates on Endothelial Function in Persons With Metabolic Syndrome
Status: COMPLETED
Conditions: Metabolic Syndrome
Interventions: DIETARY_SUPPLEMENT: Blend 1|DIETARY_SUPPLEMENT: Blend 2|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Home-based Exercise on Functional Capacity of Covid-19 Survivor With Cardiovascular Comorbidity
Status: COMPLETED
Conditions: Covid19|Breathing Exercise|Cardiovascular Diseases
Interventions: BEHAVIORAL: Breathing and chest mobilization exercises|BEHAVIORAL: Second phase cardiac rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Quantitative Sensory Testing and PET/CT Scanning in Assessment of Surgical Outcome for Lumbar Disc Herniation
Status: COMPLETED
Conditions: Lumbar Disc Herniation|Radiculopathy Lumbar
Interventions: DIAGNOSTIC_TEST: PET/CT scan|DIAGNOSTIC_TEST: Quantitative Sensory Testing
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparing Laparoscopic and Open Surgery for Pancreatic Carcinoma
Status: RECRUITING
Conditions: Pancreatic Carcinoma|Laparoscopic|Pancreaticoduodenectomy
Interventions: PROCEDURE: TLPD Surgery|PROCEDURE: OPD Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Upper and Lower Extremity Isometrics on Cognition in Healthy Adolescents
Status: COMPLETED
Conditions: Healthy Adolescents
Interventions: OTHER: Alternating unilateral Isometric Handgrip Exercise|OTHER: Dominant knee extension Isometric Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: BMS-986156, Ipilimumab, and Nivolumab With or Without Stereotactic Body Radiation Therapy in Treating Patients With Advanced or Metastatic Lung/Chest or Liver Cancers
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Malignant Solid Neoplasm|Metastatic Carcinoma in the Liver|Metastatic Carcinoma in the Lung|Metastatic Malignant Neoplasm in the Thoracic Cavity|Metastatic Malignant Solid Neoplasm
Interventions: DRUG: Anti-GITR Agonistic Monoclonal Antibody BMS-986156|BIOLOGICAL: Ipilimumab|BIOLOGICAL: Nivolumab|RADIATION: Stereotactic Body Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Thermo-plastic Versus Carbon Foot Ankle Orthosis to Improve Gait and Reduce Fatigue in Post-stroke Patients: a Biomechanical and Neurophysiological Study
Status: COMPLETED
Conditions: Hemiparesis;Poststroke/CVA|Gait, Hemiplegic
Interventions: DEVICE: Ankle Foot orthosis (AFO)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Supervised Motor Control Exercises on Rotator Cuff Tendinopathies
Status: COMPLETED
Conditions: Shoulder Impingement Syndrome|Shoulder Rotator Cuff Tendinopathy
Interventions: OTHER: Upper Extremity Neuromuscular Training Program|OTHER: Usual Physiotherapy Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of a Donor Lymphocyte Preparation Depleted of Functional Host Alloreactive T-cells (ATIR) in Patients Undergoing a Peripheral Blood Stem Cell Transplant From a Related, Haploidentical Donor
Status: TERMINATED
Conditions: Myeloid Leukemia|Lymphoblastic Leukemia|Lymphoma|Multiple Myeloma|Myelodysplastic Syndrome|Myeloproliferative Disorders
Interventions: BIOLOGICAL: Donor lymphocyte preparation depleted of host functional alloreactive T-cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Insulin and Abatacept in Recently-diagnosed Type 1 Diabetes
Status: ACTIVE_NOT_RECRUITING
Conditions: Type 1 Diabetes|Diabetes Mellitus, Type 1
Interventions: DRUG: Abatacept (CTLA4-Ig) and nasal insulin (Humulin R®)|DRUG: Abatacept (CTLA4-Ig) and nasal placebo (0.9% sodium chloride)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Gemcitabine/Taxotere/Xeloda (GTX) in Combination With Cisplatin and Irinotecan in Subjects With Metastatic Pancreatic Cancer
Status: COMPLETED
Conditions: Metastatic Pancreatic Adenocarcinoma
Interventions: DRUG: Gemcitabine|DRUG: Taxotere|DRUG: Xeloda|DRUG: Cisplatin|DRUG: Irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of an Increased Restrictive Factor of One Anastomosis Gastric Bypass on Metabolic Outcomes Type 2 Diabetes.
Status: COMPLETED
Conditions: Obesity, Morbid|Diabetes Mellitus, Type 2
Interventions: PROCEDURE: One anastomosis gastric bypass with combined fundoplication|PROCEDURE: One anastomosis gastric bypass without combined fundoplication
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Urinary Incontinence in Men After Prostatectomy With Autologous Adipose-derived Mesenchymal Stem Cells
Status: COMPLETED
Conditions: Urinary Incontinence
Interventions: BIOLOGICAL: Autologous adipose-derived mesenchymal stem cells|OTHER: Standard treatment according to the Clinical protocols
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non-Invasive Respiratory Monitor
Status: RECRUITING
Conditions: Neuromuscular Diseases|Healthy Volunteers
Interventions: DEVICE: pneuRIP (breathing with resistance)|DEVICE: Respitrace system (Carefusion) (breathing without resistance)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: High-definition Transcranial Electrical Stimulation for Upper Extremity Rehabilitation
Status: RECRUITING
Conditions: Stroke
Interventions: DEVICE: HD-tES|DEVICE: Sham HD-tES|OTHER: UE rehabilitation|DEVICE: HD-tES (Bilateral)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Influence of nCPAP on Metabolic Consequences Associated With OSAS
Status: COMPLETED
Conditions: Obstructive Sleep Apnea Syndrome|Obesity
Interventions: PROCEDURE: nasal continuous positive airway pressure
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE