pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Facilitating Adaptive Coping With Fear of Recurrence Among Breast Cancer Survivors
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Neoplasm|Breast Cancer|Breast Carcinoma|Malignant Neoplasm of Breast|Cancer of Breast|Mammary Neoplasms, Human|Human Mammary Carcinoma|Malignant Tumor of Breast|Mammary Cancer|Mammary Carcinoma, Human|Anxiety|Fear
Interventions: BEHAVIORAL: Enhanced Usual Care|BEHAVIORAL: Acceptance Commitment Therapy|BEHAVIORAL: Cognitive Behavioral Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effectiveness of a Workplace "Sit Less and Move More" Web-based Program in Spanish Office Employees (Walk@WorkSpain)
Status: COMPLETED
Conditions: Sedentary Lifestyle|Workplace|Quality of Life|Intervention Study
Interventions: BEHAVIORAL: A workplace "sit less and move more" web-based program for Spanish office employees|BEHAVIORAL: Active Comparison group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: MCS110 in Patients With Pigmented Villonodular Synovitis (PVNS)
Status: COMPLETED
Conditions: Pigmented Villonodular Synovitis|PVNS|Giant Cell Tumor of the Tendon Sheath|GCCTS|Tenosynovial Giant Cell Tumor Localized or Diffused Type|GCTS
Interventions: DRUG: MCS110|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Single Center 2-way Crossover Study to Investigate the Mechanism of Action of Etoricoxib in Subjects With Osteoarthritis Knee Pain
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DRUG: Etoricoxib, followed by placebo (matching tablet, without active ingredient)|DRUG: Placebo (matching tablet, without active ingredient), followed by etoricoxib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety and Immunogenicity of Three V181 Dengue Vaccine Potencies in Adults (V181-003)
Status: COMPLETED
Conditions: Dengue Disease|Dengue Virus
Interventions: BIOLOGICAL: V181 High-Potency Level|BIOLOGICAL: V181 Mid-Potency Level|BIOLOGICAL: V181 Low-Potency Level|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Spinal or Epidural Fentanyl or Sufentanil for Labour Pain in Early Phase of the Labour
Status: COMPLETED
Conditions: Labor Pain
Interventions: DRUG: Spinal analgesia for labour pain|DRUG: Epidural analgesia for labour pain
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ruxolitinib in Combination With Pemetrexed/Cisplatin in Non Small Cell Lung Cancer
Status: TERMINATED
Conditions: NSCLC (Non-small Cell Lung Carcinoma)
Interventions: DRUG: Ruxolitinib|DRUG: Placebo|DRUG: Pemetrexed|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Hepatitis C Clearance on Insulin Resistance
Status: COMPLETED
Conditions: Insulin Resistance|Hepatitis C
Interventions: DRUG: Sofosbuvir 400 milligram|DRUG: Daclatasvir 60 milligram|DRUG: Ribavirin 400 milligram|DRUG: Ledipasvir 90milligram/Sofosbuvir 400 milligram Tab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Japanese phase1 Study of Belimumab (IV vs SC)
Status: COMPLETED
Conditions: Systemic Lupus Erythematosus
Interventions: DRUG: GSK1550188 IV|DRUG: GSK1550188 SC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Phase II Trial of Cisplatin-Docetaxel Induction Plus Concurrent 3-D Conformal Radiotherapy and Weekly Chemotherapy
Status: COMPLETED
Conditions: Locally Advanced Non-small Cell Lung Cancer
Interventions: DRUG: Docetaxel|RADIATION: concomitant radiotherapy|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety and Concentrations of Monoclonal Antibody Against Virus That Causes COVID-19 Disease.
Status: COMPLETED
Conditions: COVID-19 Virus Disease
Interventions: BIOLOGICAL: MAD0004J08|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CHronic Hepatopathies Associated With ALcohol Consumption aNd metAbolic Syndrome
Status: NOT_YET_RECRUITING
Conditions: Non-Alcoholic Fatty Liver Disease|Non-Alcoholic Steatohepatitis|Alcohol-related Liver Disease|Cirrhosis, Liver|Hepatocellular Carcinoma
Interventions: DIAGNOSTIC_TEST: Liver biopsy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Nimotuzumab Combined With Paclitaxel for Recurrent Metastatic Gastric or Esophagogastric Junction Adenocarcinoma
Status: RECRUITING
Conditions: Gastric or Esophagogastric Junction Adenocarcinoma
Interventions: DRUG: nimotuzumab plus paclitaxel|DRUG: placebo plus paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Jump Start on the Go: Improving Resiliency and the Social-Emotional Development of At-Risk Preschool Children
Status: NOT_YET_RECRUITING
Conditions: Mental Health Wellness 1
Interventions: BEHAVIORAL: Jump Start on the Go|BEHAVIORAL: Jump Start Plus Coronavirus Support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Normatec Pump for Relief of Leg Edema
Status: UNKNOWN
Conditions: Edema|Heart Failure|Pulmonary Hypertension
Interventions: DEVICE: NormaTec Pump
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: tDCS and Aphasia Therapy in the Acute Phase After Stroke
Status: TERMINATED
Conditions: Aphasia Following Cerebral Infarction
Interventions: DEVICE: tDCS|BEHAVIORAL: Aphasia therapy|DEVICE: Sham-tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Visualising c-MET and Activated Neutrophils in Lung Cancer
Status: TERMINATED
Conditions: Lung Cancer
Interventions: OTHER: Optical Imaging Agents (EMI-137, NAP)|DEVICE: Delivery Device Cathetar and Miniaturised imaging fibre|DEVICE: Optical endomicroscopy system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Anesthesia for Upper Endoscopy and Colonoscopy in Cardiac Patients With Acute Anemia
Status: UNKNOWN
Conditions: Anemia|Cardiomyopathies|Pulmonary Hypertension
Interventions: DRUG: Etomidate|DRUG: Ketamine Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Dexlansoprazole MR-Based Concomitant Quadruple Therapy
Status: COMPLETED
Conditions: Helicobacter Pylori Infection
Interventions: DRUG: Dexlan|DRUG: Amoxicillin|DRUG: Clarithromycin 500mg|DRUG: Metronidazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Image-guided Targeted Doxorubicin Delivery With Hyperthermia to Optimize Loco-regional Control in Breast Cancer
Status: UNKNOWN
Conditions: Metastatic Breast Cancer|Breast Cancer|Breast Neoplasms|Stage IV Breast Cancer|Metastatic Cancer|Invasive Ductal Carcinoma of Female Breast|Invasive Ductal Breast Cancer|Adenocarcinoma Breast
Interventions: DRUG: LTLD|PROCEDURE: MR-HIFU induced hyperthermia|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Staged and Combined Surgery for Cataract Patients With Corneal Endothelial Dysfunction
Status: UNKNOWN
Conditions: Cataract|Corneal Endothelial Keratopathy|Phacoemulfisication+IOL Implantation|Endothelial Keratopathy
Interventions: PROCEDURE: Staged phacoemulsification and DMEK|PROCEDURE: Combined phacoemulsification and DMEK|DEVICE: Intraocular lens (IOL) implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Study of Micafungin (FK463) Versus Placebo as Prophylactic Antifungal Therapy in the ICU
Status: TERMINATED
Conditions: Invasive Fungal Infections
Interventions: DRUG: Micafungin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: High-Intensity Interval vs. Moderate Continuous Training in Surgical Prehabilitation.
Status: COMPLETED
Conditions: Colorectal Cancer|Physical Activity
Interventions: PROCEDURE: HIT|PROCEDURE: MCT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Outcome and Fusion Results Using the SiJoin® Transfixing Sacroiliac Fusion Device
Status: ENROLLING_BY_INVITATION
Conditions: Sacroiliitis|Sacroiliac Joint Dysfunction|Iatrogenic Injury|Osteitis Condensans Ilii|Pelvic Fracture
Interventions: PROCEDURE: SiJoin® Transfixing Sacroiliac Fusion Device
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Optimizing Exposure Using Occasional Aversive Imagery in Spider Fearful Individuals
Status: COMPLETED
Conditions: Spider Fear|Arachnophobia
Interventions: BEHAVIORAL: occasional aversive imagination|BEHAVIORAL: Exposure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Physostigmine After General Anesthesia
Status: UNKNOWN
Conditions: Postoperative Nausea and Vomiting|Anesthesia Recovery Period
Interventions: DRUG: physostigmine|DRUG: Isotonic sodium chloride solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Quality of Life in Food Allergic Families
Status: COMPLETED
Conditions: Food Allergy
Interventions: BEHAVIORAL: Counseling|BEHAVIORAL: Placebo phone call
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Optimizing Post-operative Recovery in Bariatric Patients With Obstructive Sleep Apnea Undergoing Outpatient Surgery: A Comparison of Sugammadex and Neostigmine
Status: COMPLETED
Conditions: Anesthesia
Interventions: DRUG: Sugammadex|DRUG: Neostigmine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Comparison of Static Air Support Devices (Repose®) and Alternating-Pressure Devices in the Prevention of Pressure Ulcers
Status: COMPLETED
Conditions: Pressure Ulcer|Pressure Injury|Pressure Sore|Bed Sore
Interventions: DEVICE: Repose®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Appropriate Level of Continuous Adductor Canal Block in Patients Undergoing Total Knee Arthroplasty (TKA)
Status: COMPLETED
Conditions: Degenerative Arthritis
Interventions: PROCEDURE: the three different sites of continous adductor canal block: the adductor canal catheter is inserted at femoral triangle apex|PROCEDURE: the three different sites of continous adductor canal block: the adductor canal catheter is inserted femur length/15*2 cm above the location|PROCEDURE: the three different sites of continous adductor canal block: the adductor canal catheter is inserted femur length/15 cm below the location
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Different Oral Hygiene Instructions
Status: COMPLETED
Conditions: Oral Hygiene Education|Oral Hygiene Education Methods
Interventions: BEHAVIORAL: Behavioral: Verbal Oral Hygiene Instructions|BEHAVIORAL: Behavioral: Video-Based Oral Hygiene Instructions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Adding Mirtazapine to Dexamethasone and Aprepitant for Delayed Emesis
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Aprepitant|DRUG: Mirtazapine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Effect of Romosozumab (AMG 785) on Bone Quality of the Forearm in Postmenopausal Women With Low Bone Mass
Status: COMPLETED
Conditions: Osteopenia
Interventions: DRUG: Romosozumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ocular Pharmacokinetics After a Single Drop Instillation of T1225 0.5, 1, 1.5% in 91 Healthy Volunteers
Status: COMPLETED
Conditions: Eye Infections, Bacterial
Interventions: DRUG: Azithromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Interstitial Cystitis/Painful Bladder Syndrome Using Alternative Techniques: Exercise, Meditation, Tai Chi
Status: WITHDRAWN
Conditions: Cystitis, Interstitial
Interventions: PROCEDURE: Alternative Medicine|PROCEDURE: Tai Chi instruction and class participation or walking exercise and sitting meditation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study to Evaluate the Efficacy and Safety of Tacrolimus in Kidney Transplant Recipients (BLOSSOM)
Status: UNKNOWN
Conditions: Kidney Transplant
Interventions: DRUG: TacroBell SR cap.|DRUG: Tacrolimus cap.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Of The Efficacy And Safety Of Sunitinib In Patients With Advanced Well-Differentiated Pancreatic Neuroendocrine Tumors
Status: COMPLETED
Conditions: Well-differentiated Pancreatic Neuroendocrine Tumor
Interventions: DRUG: sunitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: OTHER
Clinical trial: Improving Physical Health in Patients With Psychiatric Disorders in General Practice (SOFIA)
Status: COMPLETED
Conditions: Psychiatric Disorder|Schizophrenia|Bipolar Disorder|Severe Depression
Interventions: OTHER: SOFIA model
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Transcranial Magnetic Stimulation vs Theta Burst Stimulation in Major Depressive Disorder
Status: ENROLLING_BY_INVITATION
Conditions: Major Depressive Disorder
Interventions: DEVICE: Transcranial Magnetic Stimulation|DEVICE: Theta Burst Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Volontary Inspiratory Muscles Measures Compared With Phrenic Nerves Magnetic Stimulations Measures
Status: TERMINATED
Conditions: Neuromuscular Diseases|Respiratory Failure
Interventions: OTHER: Phrenic nerves magnetic stimulations
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Efficacy of Activated Recombinant Human Factor VII in Healthy Volunteers Treated for Punch Biopsy Mediated Bleeding
Status: TERMINATED
Conditions: Haemostasis|Healthy
Interventions: DRUG: eptacog alfa (activated)|DRUG: clopidogrel|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: BFR DISTRAD NON OP: Blood Flow Restricted Training During Rehabilitation Following Distal Radius Fracture
Status: UNKNOWN
Conditions: Distal Radius Fracture|Rehabilitation
Interventions: DEVICE: DELFI PTS ii portable tourniquet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Soy Phytoestrogens and Acupuncture on Bone Mineral Density in Female Athlete Triad at Adolescence Age
Status: COMPLETED
Conditions: Osteoporosis, Osteopenia
Interventions: DEVICE: Acupuncture needles|DIETARY_SUPPLEMENT: Soy phytoestrogens
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Prospective Randomized Controlled Multicenter Trial of Delayed Gastric Emptying (DGE) After Pancreaticoduodenectomy Evaluating by Gastrointestinal Reconstruction
Status: UNKNOWN
Conditions: Postprocedural Delayed Gastric Emptying
Interventions: PROCEDURE: Retrocolic gastro- or duodeno- jejunostomy in hte pancreaticoduodenectomy|PROCEDURE: Antecolic gastro- or duodeno- jejunostomy in the pancreaticoduodenectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Non-Invasive Neurostimulation for the Prevention of Chronic Migraine
Status: COMPLETED
Conditions: Chronic Migraine
Interventions: DEVICE: GammaCore Active Device|DEVICE: GammaCore Sham Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Trial to Assess the Effect and Safety of the C-Qur™ Film
Status: UNKNOWN
Conditions: Postoperative Adhesions
Interventions: DEVICE: C-Qur
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Spinal Cord Stimulation Pioneering Analgesia for Resilient Recovery in Post Intra-Thoracic Surgery Pain
Status: NOT_YET_RECRUITING
Conditions: Pain, Postoperative|Neuropathic Pain
Interventions: DEVICE: Spinal Cord Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Master Protocol to Study Treatment Patterns, Medication Adherence, Health and Economic Outcomes and Unmet Needs in RCC
Status: COMPLETED
Conditions: Renal Cell Carcinoma (RCC)
Interventions: DRUG: Tyrosine kinase inhibitor (TKI)|DRUG: Immuno-oncology (IO)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Enhancing Digitally Delivered Diabetes Education With Real-Time CGM
Status: NOT_YET_RECRUITING
Conditions: Diabetes Type 2
Interventions: OTHER: Dulce Digital Text Messaging Intervention|OTHER: CGM Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phase Ib/II Study Assessing the Neo-adjuvant Combination Therapy of Vinflunine With Cisplatin Followed by Radical Cystectomy in Patients With Muscle-invasive Bladder Cancer (JaNEO)
Status: WITHDRAWN
Conditions: Bladder Cancer
Interventions: DRUG: Vinflunine|DRUG: Cisplatin|PROCEDURE: Radical cystectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Home-based EXergames To impRove cognitivE Function in MUltiple Sclerosis
Status: UNKNOWN
Conditions: Multiple Sclerosis
Interventions: BEHAVIORAL: Exergames|BEHAVIORAL: Adaptive COGNI-TRAcK|BEHAVIORAL: Sham COGNI-TRAcK
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Application of Auricular Point Sticking in Patients With Taste Alteration
Status: COMPLETED
Conditions: Dysgeusia|Acupressure|Chemotherapy Effect
Interventions: BEHAVIORAL: auricular point sticking
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: the Investigation of Therapeutic Effect and Platelet Activity After ILIB for Ischemic Stroke Patient
Status: RECRUITING
Conditions: Ischemic Stroke
Interventions: DEVICE: Intravascular laser irradiation of blood
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy in Treating Patients With Newly Diagnosed Stage III or Stage IV Non-Hodgkin's Lymphoma
Status: UNKNOWN
Conditions: Lymphoma
Interventions: DRUG: chlorambucil|DRUG: dexamethasone|DRUG: fludarabine phosphate|DRUG: mitoxantrone hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Effect of Behavioral Nudges on Serious Illness Conversation Documentation
Status: COMPLETED
Conditions: Cancer
Interventions: OTHER: Usual Care|OTHER: Clinician Nudge|OTHER: Patient Nudge
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Metabo-lipidomics of the Ocular Surface for Cataract Surgery
Status: RECRUITING
Conditions: Age-related Cataract
Interventions: OTHER: Ocular Surface Disease Index|OTHER: Interferometry|OTHER: Oxford score|OTHER: Conjunctival collection|OTHER: Aqueous humor collection|OTHER: Quantification of Tyndall and flare
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study to Evaluate NA-NOSE for Monitoring and Detecting Recurrence in Early Stage Lung Cancer
Status: COMPLETED
Conditions: Stage IA Non-small Cell Lung Cancer|Stage IB Non-small Cell Lung Cancer|Stage IIA Non-small Cell Lung Cancer|Stage IIB Non-small Cell Lung Cancer
Interventions: PROCEDURE: breath test|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study Comparing Different Dosing Regimens of Ixekizumab (LY2439821) in Participants With Moderate to Severe Plaque Psoriasis
Status: COMPLETED
Conditions: Plaque Psoriasis
Interventions: DRUG: Ixekizumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Peridontal and Intestinal Microbiota in Patients With Gingival Scarring Pemphigoid
Status: NOT_YET_RECRUITING
Conditions: Pemphigoid, Benign Mucous Membrane|Gingivitis Hyperplastic
Interventions: OTHER: Plaque sampling and stool collection|OTHER: periodontal examination
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase II Trial of Triapine (NSC #663249) in Combination With Gemcitabine as Second Line Treatment of Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Recurrent Non-small Cell Lung Cancer
Interventions: DRUG: triapine|DRUG: gemcitabine hydrochloride|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic, Efficacy, Safety and Tolerability Study of a Single Dose of Acoziborole in g-HAT Paediatric Patients
Status: UNKNOWN
Conditions: Trypanosomiasis, African|Trypanosoma Brucei Gambiense; Infection|Sleeping Sickness
Interventions: DRUG: Acoziborole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 3 Single-Arm Study of UGN-102 for Treatment of Low Grade Intermediate Risk Non-Muscle-Invasive Bladder Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Bladder Cancer|Urothelial Carcinoma|Urothelial Carcinoma Bladder
Interventions: DRUG: UGN-102
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Impact of Food Reformulation on Energy Intake
Status: COMPLETED
Conditions: Diet, Healthy|Eating Behavior|Obesity
Interventions: BEHAVIORAL: Low energy density lunch|BEHAVIORAL: Medium energy density lunch|BEHAVIORAL: High energy density lunch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: To Investigate the Efficacy and Safety of OPC-6535 in Chronic Obstructive Pulmonary Disease (COPD) Patients
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: tetomilast (OPC-6535)|DRUG: tetomilast (OPC-6535)|DRUG: tetomilast (OPC-6535)|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Effects of Mecamylamine and Varenicline in Schizophrenia
Status: COMPLETED
Conditions: Cognition in Schizophrenia
Interventions: DRUG: Mecamylamine|DRUG: Varenicline|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Fecal Transplantation for Primary Clostridium Difficile Infection
Status: UNKNOWN
Conditions: Clostridium Difficile Infection
Interventions: OTHER: Fecal microbiota transplantation|DRUG: Vancomycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Modified-release Compared to Conventional Hydrocortisone on Diurnal Fatigue in Secondary Hypoadrenalism
Status: UNKNOWN
Conditions: Adrenal Insufficiency
Interventions: DRUG: Hydrocortisone|DRUG: Plenadren
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A 5 Day Course of Fludarabine and Cytarabine Followed by Full Intensity Allogeneic Stem Cell Transplantation (FA5-Bucy) in Treating Patients With High-risk, Recurrent or Refractory Acute Leukemia and Advanced Myelodysplastic Syndrome
Status: UNKNOWN
Conditions: Myelodysplastic Syndromes|Leukemia, Myeloid, Acute|Precursor Cell Lymphoblastic Leukemia-Lymphoma
Interventions: DRUG: Fludarabine and Cytarabine followed by IV busulfan and cyclophosphamide
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Use of TRC Autologous Bone Marrow Cells in Posterolateral Lumbar Spine Fusion
Status: TERMINATED
Conditions: Single Level Posterolateral Spinal Fusion
Interventions: BIOLOGICAL: Bone Repair Cells (BRCs)|PROCEDURE: Autologous bone graft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Night-time Compression Systems for Breast Cancer Related Lymphedema
Status: COMPLETED
Conditions: Breast Neoplasms|Lymphedema
Interventions: BEHAVIORAL: Night-time compression system garment|BEHAVIORAL: Day-time compression sleeve
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Paclitaxel Compared With Doxorubicin in Treating Patients With Advanced AIDS-Related Kaposi's Sarcoma
Status: COMPLETED
Conditions: AIDS-related Kaposi Sarcoma
Interventions: DRUG: paclitaxel|DRUG: pegylated liposomal doxorubicin hydrochloride|OTHER: laboratory biomarker analysis|PROCEDURE: quality-of-life assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Retrograde Colonic Irrigation to Manage Spina Bifida Functional Digestive Sequelae: a Multicenter, Prospective, Randomized Controlled Trial
Status: COMPLETED
Conditions: Spina Bifida
Interventions: DEVICE: Retrograde Colonic Irrigation|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Sacubitril/Valsartan on Reduced Right Ventricular Ejection Fraction in Patients With CTD
Status: UNKNOWN
Conditions: Myocardial Injury|Connective Tissue Diseases
Interventions: DRUG: Sacubitril / Valsartan Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Examining the Effects of Nebivolol Compared to Atenolol on Endothelial Function
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Nebivolol|DRUG: atenolol|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination of Toripalimab and Neoadjuvant Chemoradiotherapy for Locally Advanced Esophageal Squamous Cell Carcinoma
Status: UNKNOWN
Conditions: Esophageal Squamous Cell Carcinoma
Interventions: DRUG: Toripalimab|DRUG: Paclitaxel liposome/Carboplatin|RADIATION: Intensity-modulated radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: DTG/3TC Fixed Dose Formulations for the Maintenance of Virological Suppression in Children With HIV Infection Aged 2 to <15 Years Old
Status: RECRUITING
Conditions: HIV Infections
Interventions: DRUG: Dolutegravir (DTG) and lamivudine (3TC)|DRUG: SOC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Investigating Role of Unalike Patient Positioning on PROMIS Scores
Status: COMPLETED
Conditions: Physical Activity|Surgery|Vaginal Hysterectomy|Vaginal Surgery
Interventions: PROCEDURE: Vaginal Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phase 2 Pilot Study to Evaluate the Safety and Efficacy of RM-131 Administered to Females With Anorexia Nervosa
Status: COMPLETED
Conditions: Anorexia Nervosa
Interventions: DRUG: RM-131|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Relationship Between Oxytocin Level, Trust, and Attachment in Individuals With Borderline Personality Disorder
Status: NOT_YET_RECRUITING
Conditions: Borderline Personality Disorder
Interventions: OTHER: baseline serum oxytocin levels|OTHER: Emotional Sensitivity test|OTHER: Neuro-economical game|OTHER: Childhood Trauma Questionnaire|OTHER: Relationships Questionnaire|OTHER: demographic questionnaire
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Treatment of the Human Anti-TNF Monoclonal Antibody Adalimumab in Moderate to Severe Crohn's Disease With Previous Exposure to Infliximab (CHOICE)
Status: COMPLETED
Conditions: Crohn's Disease
Interventions: DRUG: adalimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of Orthokeratology Lens (MCOK-01)
Status: ACTIVE_NOT_RECRUITING
Conditions: Myopia
Interventions: DEVICE: Test orthokeratology lens|DEVICE: Control orthokeratology lens
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Blood Tests and Questionnaires in Studying Adherence to Preventative Swallowing Exercises in Participants With Metastatic Head and Neck Cancer
Status: RECRUITING
Conditions: Carcinoma of Unknown Primary|Clinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8|Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8|Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8|Metastatic Head and Neck Carcinoma|Metastatic Malignant Neoplasm in the Uterine Cervix|Pathologic Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8|Pathologic Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8|Pathologic Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8|Stage I Hypopharyngeal Carcinoma AJCC v8|Stage I Nasopharyngeal Carcinoma AJCC v8|Stage II Hypopharyngeal Carcinoma AJCC v8|Stage II Laryngeal Cancer AJCC v8|Stage II Nasopharyngeal Carcinoma AJCC v8|Stage II Oropharyngeal (p16-Negative) Carcinoma AJCC v8|Stage III Hypopharyngeal Carcinoma AJCC v8|Stage III Laryngeal Cancer AJCC v8|Stage III Nasopharyngeal Carcinoma AJCC v8|Stage III Oropharyngeal (p16-Negative) Carcinoma AJCC v8|Stage IV Hypopharyngeal Carcinoma AJCC v8|Stage IV Laryngeal Cancer AJCC v8|Stage IV Nasopharyngeal Carcinoma AJCC v8|Stage IV Oropharyngeal (p16-Negative) Carcinoma AJCC v8|Stage IVA Hypopharyngeal Carcinoma AJCC v8|Stage IVA Laryngeal Cancer AJCC v8|Stage IVA Nasopharyngeal Carcinoma AJCC v8|Stage IVA Oropharyngeal (p16-Negative) Carcinoma AJCC v8|Stage IVB Hypopharyngeal Carcinoma AJCC v8|Stage IVB Laryngeal Cancer AJCC v8|Stage IVB Nasopharyngeal Carcinoma AJCC v8|Stage IVB Oropharyngeal (p16-Negative) Carcinoma AJCC v8
Interventions: PROCEDURE: Biospecimen Collection|OTHER: Questionnaire Administration
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Blueberry Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Wild blueberry containing foods|DIETARY_SUPPLEMENT: Placebo containing foods
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of PS-IPC Supplementation on Muscle Mass and Functional Outcomes in Older Adults
Status: TERMINATED
Conditions: Immune Senescence|Sarcopenia
Interventions: DIETARY_SUPPLEMENT: Oral PS-IPC supplement|DIETARY_SUPPLEMENT: Placebo supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effective Approaches & Strategies to Ease Off Nasal CPAP In Preterm Infants
Status: COMPLETED
Conditions: Neonatal Respiratory Distress Syndrome|Extremely Low Birth Weight Infant (ELBW)|BronchoPulmonary Dysplasia
Interventions: DEVICE: NCPAP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: DT-9081 Study in Participants With Advanced, Recurrent or Metastatic Solid Tumours
Status: RECRUITING
Conditions: Solid Tumor, Adult
Interventions: DRUG: DT-9081 - dose escalation|DRUG: DT-9081 - expansion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bispectral Index and Patient State Index During General Anesthesia With Remimazolam
Status: UNKNOWN
Conditions: Remimazolam|Anesthesia, General|Hypnotics and Sedatives|Thyroid Disease|Breast Diseases|Parathyroid Diseases
Interventions: DEVICE: Bispectral index and Patient state index monitoring
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phase II Pre-operative Vitamin D Supplementation to Prevent Post-thyroidectomy Hypocalcemia
Status: COMPLETED
Conditions: Thyroid Nodules|Hypocalcemia
Interventions: DIETARY_SUPPLEMENT: Calcitriol|DIETARY_SUPPLEMENT: Control Pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Trial Comparing Routine Intraoperative Transesophageal Echocardiography During Radical Cystectomy to Standard of Care
Status: COMPLETED
Conditions: Cardiac and Pulmonary Complications. Central Venous Line Insertion. Gastrointestinal Recovery
Interventions: OTHER: Transesophageal echocardiography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effectiveness Study of Scopolamine Combined With Escitalopram in Patients With MDD
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: Scopolamine|DRUG: Escitalopram|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Capecitabine and Temozolomide for Neuroendocrine Cancers
Status: COMPLETED
Conditions: Neuroendocrine Tumors
Interventions: DRUG: Capecitabine|DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Itacitinib in Adults With Systemic Sclerosis
Status: RECRUITING
Conditions: Systemic Sclerosis
Interventions: DRUG: Itacitinib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Economic Impact of Dropless Therapy Versus Usual Care for Cataract Surgery: A Real-World Study.
Status: TERMINATED
Conditions: Cataract Surgery
Interventions: COMBINATION_PRODUCT: Dropless Therapy|DRUG: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Hypertonic Saline Solution to Prevent Acute Kidney Injury After Heart Transplantation
Status: RECRUITING
Conditions: Heart Transplantation|Acute Kidney Injury
Interventions: DRUG: Sodium chloride solution 3,5%|DRUG: Sodium chloride solution 0,9%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Suprazygomatic Maxillary Nerve Block Effect on Systemic Inflammatory Response in Cleft Palate Surgeries
Status: COMPLETED
Conditions: Perioperative Inflammatory Response|Postoperative Pain
Interventions: DRUG: Bupivacaine 0.25% Injectable Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bone Biopsy Study For Dialysis Patients With Secondary Hyperparathyroidism of End Stage Renal Disease
Status: COMPLETED
Conditions: Secondary Hyperparathyroidism
Interventions: DRUG: Sensipar (Cinacalcet HCl)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reverse Breech Extraction Versus Push Technique for Fetal Delivery When Fetal Head is Deeply Impacted in the Pelvis During CS on A Fully Dilated Cervix
Status: RECRUITING
Conditions: Obstructed Labor at Second Stage of Labor
Interventions: PROCEDURE: reverse breech extraction technique or push technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Study to Evaluate the Safety, Tolerability and Pharmacokinetic Profile of XNW7201 in Subjects With Advanced Solid Tumors
Status: COMPLETED
Conditions: Advanced Solid Tumors
Interventions: DRUG: XNW7201 tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combined tDCS and TMS on Subjective Tinnitus and Combined Depression
Status: COMPLETED
Conditions: Tinnitus|Depression
Interventions: DEVICE: transcranial direct current stimulation (tDCS) and transcranial magnetic stimulation (TMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study of Pulse Reduced Dose Rate Radiation Therapy With Bevacizumab
Status: ACTIVE_NOT_RECRUITING
Conditions: Glioma
Interventions: DRUG: Bevacizumab|RADIATION: PRDR
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An RCT of NBI vs. White Light Guided Endobronchial Biopsy in Suspected Sarcoidosis
Status: COMPLETED
Conditions: Sarcoidosis, Pulmonary
Interventions: DEVICE: Narrow band imaging bronchoscopy guided endobronchial biopsy|DEVICE: White light bronchscopy guided endobronchial biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Prediction of Massive Transfusion in Trauma Patients
Status: COMPLETED
Conditions: Trauma Injury|Haemorrhagic Shock|Bleeding|Emergencies|Blood Transfusion|Massive Hemorrhage|Massive Transfusion|Adult|Bleeding Hemorrhage|Hemorrhage / Mortality|Cohort Study|Female|Male|Hospital Mortality|Humans|Models, Theoretical|Prognosis|Wounds and Injuries / Mortality
Interventions: OTHER: Comparison of score performances (Overall performance, discrimination and calibration)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Antimalarial Treatment on Gametocyte Carriage in Asymptomatic P. Falciparum
Status: COMPLETED
Conditions: Asymptomatic P.Falciparum Malaria
Interventions: DRUG: Sulfadoxine-pyrimethamine|DRUG: Sulfadoxine-pyrimethamine plus artesunate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Eribulin in Angiosarcoma and Epithelioid Hemangioendothelioma (EHE)
Status: ACTIVE_NOT_RECRUITING
Conditions: Angiosarcoma|Epithelioid Hemangioendothelioma
Interventions: DRUG: Eribulin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bacillus Calmette-Guerin Followed by Sunitinib for the Treatment of High Risk Non-muscle Invasive Lower Urinary Tract Urothelial Carcinoma
Status: COMPLETED
Conditions: Urinary Tract Urothelial Carcinoma
Interventions: DRUG: Sunitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Impact of the Intervention of a Pharmacist in the Operating Room on the Appropriate Use of Sterile Medical deviceS
Status: COMPLETED
Conditions: Surgery
Interventions: OTHER: impact of the intervention of a clinical pharmacist with expertise in sterile medical devices on non-compliances related to the use of sterile medical devices
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Stainless Steel Crowns Versus Bulkfill Composite Resin for Restoring Primary Molars After Endodontic Treatment
Status: COMPLETED
Conditions: Dental Caries
Interventions: PROCEDURE: Restoration with Stainless Steel Crowns|PROCEDURE: Restoration using BulkFill CR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharyngeal Airway Dimensions With Twinblock Versus Myobrace Appliances in Developing Skeletal Class II Patients
Status: COMPLETED
Conditions: Malocclusion, Angle Class II, Division 1
Interventions: DEVICE: Myobrace Functional Appliance|DEVICE: Twin Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cediranib Maleate in Treating Patients With Relapsed, Refractory, or Untreated Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome
Status: COMPLETED
Conditions: Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities|Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)|Adult Acute Myeloid Leukemia With t(15;17)(q22;q12)|Adult Acute Myeloid Leukemia With t(16;16)(p13;q22)|Adult Acute Myeloid Leukemia With t(8;21)(q22;q22)|de Novo Myelodysplastic Syndromes|Previously Treated Myelodysplastic Syndromes|Recurrent Adult Acute Myeloid Leukemia|Secondary Acute Myeloid Leukemia|Secondary Myelodysplastic Syndromes|Untreated Adult Acute Myeloid Leukemia
Interventions: DRUG: cediranib maleate|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Monoclonal Antibody Therapy Plus Chemotherapy Followed by Peripheral Stem Cell Transplantation in Treating Patients With Metastatic Prostate Cancer That Has Not Responded to Hormone Therapy
Status: UNKNOWN
Conditions: Prostate Cancer
Interventions: BIOLOGICAL: filgrastim|BIOLOGICAL: monoclonal antibody m170|DRUG: cyclosporine|DRUG: paclitaxel|PROCEDURE: peripheral blood stem cell transplantation|RADIATION: indium In 111 monoclonal antibody m170|RADIATION: yttrium Y 90 monoclonal antibody m170
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effective Methods of Reducing Lower Back, Neck and Shoulder Pain Among Office Workers
Status: COMPLETED
Conditions: Musculoskeletal Pain|Low Back Pain
Interventions: OTHER: office exercise training|OTHER: ergonomic modification|OTHER: Exercise and ergonomic|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC