pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Study to Evaluate the Safety and Pharmacokinetics of Regadenoson in Pediatric Patients
Status: RECRUITING
Conditions: Myocardial Ischemia|Coronary Artery Disease
Interventions: DRUG: Regadenoson
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Clinical Trial for the Prevention of Vasovagal Syncope
Status: COMPLETED
Conditions: Syncope, Vasovagal, Neurally-Mediated
Interventions: DRUG: fludrocortisone acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Selexipag Assessing Right Ventricular Remodeling in Pulmonary Arterial Hypertension by Cardiac Magnetic Resonance Imaging
Status: TERMINATED
Conditions: Pulmonary Arterial Hypertension
Interventions: DRUG: JNJ-67896049
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Impact and Adverse Events of Topical Eyedrops of AGN-190584 on Night-driving Performance in Participants, 40 to 55 Years of Age
Status: COMPLETED
Conditions: Presbyopia
Interventions: DRUG: AGN-190584
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Graded Protein Intake on Body Composition in Older Adults
Status: UNKNOWN
Conditions: Sarcopenia
Interventions: DIETARY_SUPPLEMENT: Graded Protein plus Resistance Training|DIETARY_SUPPLEMENT: RDA Protein plus Resistance Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Phase II Study of Crenolanib in Relapsed/Refractory Acute Myeloid Leukemia Patients With FLT3 Activating Mutations
Status: COMPLETED
Conditions: Acute Myeloid Leukemia With FLT3 Activating Mutations That Has Relapsed or Been Refractory After One or More Prior Therapies
Interventions: DRUG: Crenolanib besylate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Individualized-Exercise Based Cardiac Rehabilitation Programs in Patients With Acute Myocardial Infarction
Status: UNKNOWN
Conditions: Acute Myocardial Infarction
Interventions: BEHAVIORAL: Exercise-based cardiac rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Glyburide Advantage in Malignant Edema and Stroke - Remedy Pharmaceuticals
Status: COMPLETED
Conditions: Ischemic Stroke|Malignant Edema
Interventions: DRUG: Glyburide for Injection|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Exemestane With or Without Entinostat in Treating Patients With Recurrent Hormone Receptor-Positive Breast Cancer That is Locally Advanced or Metastatic
Status: ACTIVE_NOT_RECRUITING
Conditions: Anatomic Stage III Breast Cancer AJCC v8|Anatomic Stage IV Breast Cancer AJCC v8|Breast Adenocarcinoma|HER2/Neu Negative|Locally Advanced Breast Carcinoma|Metastatic Breast Carcinoma|Recurrent Breast Carcinoma
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|DRUG: Entinostat|DRUG: Exemestane|DRUG: Goserelin|DRUG: Goserelin Acetate|PROCEDURE: Magnetic Resonance Imaging|OTHER: Placebo Administration|OTHER: Quality-of-Life Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Erlotinib in Treating Patients With Malignant Mesothelioma of the Lung
Status: COMPLETED
Conditions: Advanced Malignant Mesothelioma|Epithelial Mesothelioma|Recurrent Malignant Mesothelioma|Sarcomatous Mesothelioma
Interventions: DRUG: erlotinib hydrochloride|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Intravenous Iron Therapy in Maintaining Hemoglobin Concentration on Patients Undergoing Bimaxillary Orthognathic Surgery
Status: UNKNOWN
Conditions: Facial Asymmetry|Retrognathism|Prognathism
Interventions: DRUG: Iron Isomaltoside 1000|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pilocarpine in Treating Vaginal Dryness in Patients With Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer|Vaginal Dryness
Interventions: DRUG: pilocarpine hydrochloride|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Comparison of the Drug Therapy Versus Re-Ablation
Status: COMPLETED
Conditions: Paroxysmal Atrial Fibrillation|Failed First Radiofrequency Ablation Procedure
Interventions: DRUG: Anti-Arrhythmia Agents (propafenone, flecainide, and/or sotalol, or amiodarone)|PROCEDURE: re-ablation procedure|PROCEDURE: ILR implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 2a, Dose-ranging Study With PF-05221304 in Nonalcoholic Fatty Liver Disease (NAFLD)
Status: COMPLETED
Conditions: Nonalcoholic Fatty Liver Disease|Nonalcoholic Steatohepatitis
Interventions: DRUG: Placebo|DRUG: PF-05221304
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Reducing Fasting Time in Children for Sedation
Status: COMPLETED
Conditions: Pediatric ALL
Interventions: OTHER: 4 hours of fasting time|OTHER: 2 hours of fasting time
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy of Viusid and Asbrip in Hospitalized Patients Infected by SARS-Cov-2 With COVID-19
Status: COMPLETED
Conditions: Covid-19|Sars-CoV2|Diabete Mellitus|Cardiopathy|Pulmonary Disease|Renal Disease|Liver Diseases
Interventions: DIETARY_SUPPLEMENT: Viusid and Asbrip
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Developing a Team-Delivered Intervention for Smoking and Hazardous Drinking for Primary Care Veterans With Cardiovascular Diseases
Status: COMPLETED
Conditions: Cigarette Use|Alcohol Use Above Recommended Limits|Cardiovascular Risk Factors (e.g., Hypertension)|Cardiovascular Diseases
Interventions: BEHAVIORAL: CARE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Prospective Trial of Serial CT Imaging for Evaluation of Dosimetric/Volumetric Changes During IMRT for Head/Neck Cancer
Status: COMPLETED
Conditions: Head and Neck Cancer|Head and Neck Squamous Cell Carcinoma
Interventions: RADIATION: Postop IMRT for head/neck cancer|DEVICE: CT for Radiation Treatment Planning
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Non-steroidal Anti-inflammatory Drugs (NSAIDS) on Acclimatization to High Altitude
Status: COMPLETED
Conditions: High Altitude
Interventions: DRUG: Ibuprofen|DRUG: Sugar pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Blood Salvage From Liver Donors: a Feasibility Pilot Study
Status: RECRUITING
Conditions: Liver Transplantation|Erythrocyte Transfusion
Interventions: BIOLOGICAL: Red Blood Cell concentrates from organ donor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Role of TXA in Patients Undergoing Breast Free Flap Reconstruction
Status: RECRUITING
Conditions: Breast Cancer|Blood Loss, Surgical
Interventions: DRUG: Tranexamic acid|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Intravenous Ceftolozane/Tazobactam Compared to Piperacillin/Tazobactam in Ventilator-Associated Pneumonia
Status: TERMINATED
Conditions: Ventilator-Associated Pneumonia (VAP)
Interventions: DRUG: Ceftolozane/Tazobactam|DRUG: Piperacillin/Tazobactam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Brain Plasticity Underlying Acquisition of New Organizational Skills in Children-R61 Phase
Status: COMPLETED
Conditions: ADHD|Attention Deficit Hyperactivity Disorder|Neurodevelopmental Disorders
Interventions: BEHAVIORAL: OST Intervention for participants with Organizational skill difficulties
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Drug-drug Interactions Between DZD9008 and Itraconazole/Carbamazepine
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: DZD9008 and intraconazole|DRUG: DZD9008 and carbamazepine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Clinical Randomisation of an Antifibrinolytic in Significant Head Injury
Status: COMPLETED
Conditions: Traumatic Brain Injury
Interventions: DRUG: Tranexamic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: University of Texas H.S.C. San Antonio Pioglitazone in Non-Alcoholic Steatohepatitis Trial (UTHSCSA NASH Trial)
Status: COMPLETED
Conditions: Nonalcoholic Steatohepatitis|Nonalcoholic Fatty Liver Disease|Type 2 Diabetes Mellitus
Interventions: DRUG: Pioglitazone study drug|DRUG: Placebo|DRUG: Pioglitazone Open Label
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Different Regimens of Vaniprevir (MK7009) for the Treatment of Chronic Genotype 1 Hepatitis C Virus Infection in Treatment-naive Patients (MK-7009-019)(WITHDRAWN)
Status: WITHDRAWN
Conditions: Chronic Genotype 1 Hepatitis C Virus Infection
Interventions: DRUG: vaniprevir (MK7009)|DRUG: Comparator: vaniprevir (MK7009)|DRUG: Comparator: Pegylated Interferon (peg-IFN) alfa-2a|DRUG: Comparator: Ribavirin|DRUG: Comparator: Placebo to vaniprevir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Milk, Growth and Microbiota Study
Status: SUSPENDED
Conditions: Preterm Infant|Growth Delay|Microbial Colonization|Breastfeeding|Breast Milk Substitute Intolerance
Interventions: OTHER: Donor milk|OTHER: Preterm infant formula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Aquamin F on NSAID Dose Reduction in Osteoarthritis of the Knee
Status: COMPLETED
Conditions: Osteoarthritis of the Knee
Interventions: DRUG: Aquamin F|DRUG: Placebo (maltodextran)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Bioequivalence of Lacosamide Tablet (200mg) and Syrup (10mg/ml) in Healthy Chinese Male Subjects
Status: COMPLETED
Conditions: Healthy Male Volunteers
Interventions: DRUG: Lacosamide (LCM) tablet|DRUG: Lacosamide (LCM) syrup
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Propacetamol to Reduce Post Cesarean Section Uterine Contraction Pain
Status: COMPLETED
Conditions: Uterine Pain
Interventions: DRUG: Propacetamol 1g|DRUG: Propacetamol 2g|DRUG: IVPCA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Secukinumab Compared to Fumaderm® in Adults With Moderate to Severe Psoriasis.
Status: COMPLETED
Conditions: Psoriasis
Interventions: BIOLOGICAL: Secukinumab|DRUG: Fumaric acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Breast Margin Study: Routine Cavity Shave Margins Vs. Selective Margins Using Savi Scout®
Status: RECRUITING
Conditions: Breast Cancer
Interventions: PROCEDURE: Arm 1 Partial mastectomy with Savi Scout® localization and shave margins.|PROCEDURE: Arm 2 Partial mastectomy with Savi Scout® localization and selective shave margins.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Ventricular Tachyarrhythmias Refractory To Shock With Beta Blockers: The SHOCK and BLOCK Trial
Status: TERMINATED
Conditions: Cardiac Arrest|Sudden Cardiac Death|Ventricular Fibrillation|Tachycardia, Ventricular
Interventions: DRUG: Epinephrine|DRUG: Metoprolol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of the Safety and Ability of a Once-a-day Dose of an Orally Inhaled Medicine [i.e., Glycopyrrolate Inhalation Solution = GIS] to Improve Airflow in the Lungs When Delivered Using an eFlow Nebulizer in Patients With Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Glycopyrrolate Inhalation Solution12.5μg|DRUG: Glycopyrrolate Inhalation Solution 50μg|DRUG: Glycopyrrolate Inhalation Solution 100μg|DRUG: Glycopyrrolate Inhalation Solution 200μg|DRUG: Glycopyrrolate Inhalation Solution 400μg|DRUG: Placebo 0.5mL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Individual Adult and Pediatric Patient Dose-escalated Interleukin-2 Therapy for Refractory Chronic GVHD
Status: COMPLETED
Conditions: Chronic Versus Graft Host Disease
Interventions: DRUG: Interleukin-2
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Efficacy and Safety of Paricalcitol Injection With Maxacalcitol Injection in Adult Japanese Chronic Kidney Disease Subjects Receiving Hemodialysis With Secondary Hyperparathyroidism
Status: COMPLETED
Conditions: Secondary Hyperparathyroidism|Hemodialysis
Interventions: DRUG: paricalcitol|DRUG: maxacalcitol|DRUG: paricalcitol placebo|DRUG: maxacalcitol placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Evaluate OrienX010 in Combination With Toripalimab as Neoadjuvant Treatment in Advanced Melanoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Melanoma
Interventions: BIOLOGICAL: OrienX010 Combination with Toripalimab injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Doxorubicin and Strontium-89 With or Without Celecoxib in Treating Patients With Progressive Androgen-Independent Prostate Cancer and Bone Metastases
Status: TERMINATED
Conditions: Metastatic Cancer|Prostate Cancer
Interventions: DRUG: Celecoxib|DRUG: Doxorubicin Hydrochloride|RADIATION: Strontium chloride Sr 89
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Understanding of Chest Pain in Microvascular Disease Proved by Cardiac Magnetic Resonance Image
Status: UNKNOWN
Conditions: Microvascular Angina
Interventions: DRUG: Udenafil|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of GS-1811 Given Alone or With Zimberelimab in Adults With Advanced Solid Tumors
Status: RECRUITING
Conditions: Advanced Solid Tumor
Interventions: DRUG: GS-1811|DRUG: Zimberelimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Transjugular Intrahepatic Portosystemic Shunts on Liver Stiffness
Status: TERMINATED
Conditions: Portal Hypertension|Liver Fibroses
Interventions: DIAGNOSTIC_TEST: Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: An Open-Label, Multicenter, Rollover, Long-term Study of Aripiprazole Intramuscular Depot in Participants With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Aripiprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Implementation of Physical Exercise at the Workplace (IRMA10) - Occupational Load
Status: COMPLETED
Conditions: Musculoskeletal Disorders|Stress
Interventions: BEHAVIORAL: Biopsychosocial|BEHAVIORAL: Reference
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Brain Gym® Exercises for Institutionalized Elderly People With Cognitive Impairment
Status: COMPLETED
Conditions: Cognition Disorders in Old Age|Physical Activity
Interventions: BEHAVIORAL: Brain Gym Exercises|BEHAVIORAL: Standard exercise program for institutionalized older adults.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Combination Ultra Q10 and L-carnitine on the Course of Myelodysplastic Syndrome
Status: UNKNOWN
Conditions: Myelodysplastic Syndrome
Interventions: DIETARY_SUPPLEMENT: Coenzyme Q10U, L-carnitine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Motor Learning in Gait in Subjects With Diabetic Peripheral Neuropathy
Status: COMPLETED
Conditions: Diabetes|Peripheral Neuropathy
Interventions: BEHAVIORAL: Gait Training with Feedback|BEHAVIORAL: Gait Training with no feedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: MIDRIX4-LUNG Dendritic Cell Vaccine in Patients With Metastatic Non-small Cell Lung Cancer
Status: UNKNOWN
Conditions: Non-small Cell Lung Cancer Metastatic
Interventions: BIOLOGICAL: Dendritic cell immunotherapy|BIOLOGICAL: Antigen-specific DTH|BIOLOGICAL: Control DTH
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Don't be Late! Postponing Cognitive Decline and Preventing Early Unemployment in People With Multiple Sclerosis
Status: RECRUITING
Conditions: Multiple Sclerosis
Interventions: BEHAVIORAL: Strenghtening the brain|BEHAVIORAL: Strengthening the mind
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Clinical Trial to Assess the Efficacy of Darunavir/Ritonavir (DRV/r), Etravirine (ETV) and Raltegravir (MK-0518) in HIV Patients With Resistant Viruses
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: raltegravir potassium|DRUG: darunavir/ritonavir|DRUG: etravirine|DRUG: Optimized background regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of 4 Weeks Treatment With Inhaled BI 1744 CL in Japanese Patients With COPD
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: BI 1744 CL 2 Âµg|DRUG: BI 1744 CL 5 Âµg|DRUG: BI 1744 CL 10 Âµg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Maxillary Molar Distalization Supported by Mini-implants With the Advanced Molar Distalization Appliance (Amda®)
Status: RECRUITING
Conditions: Angle Class II
Interventions: DEVICE: Advanced Molar Distalization Appliance (amda®)|DEVICE: Buccal mini-implants
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of HB0017 in Patients With Moderate to Severe Plaque Psoriasis
Status: COMPLETED
Conditions: Plaque Psoriasis
Interventions: OTHER: Placebo|DRUG: HB0017
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Activity, Safety and Pharmacokinetics in Pediatric Subjects With Moderate and Severe Chronic Graft vs. Host Disease After Allogeneic Stem Cell Transplant
Status: ACTIVE_NOT_RECRUITING
Conditions: Graft vs Host Disease
Interventions: DRUG: INC424
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reduced Opioid Prescription After Laparoscopic Hysterectomy
Status: ACTIVE_NOT_RECRUITING
Conditions: Pain, Postoperative|Opioid Misuse|Opioid Use|Pain
Interventions: DRUG: OxyCODONE 5 mg Oral Tablet|DRUG: Acetaminophen 500 mg Tab|DRUG: Ibuprofen 600 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Does a Migraine Medication Decrease Rotational Motion Sickness in People Suffering From Migraines?
Status: COMPLETED
Conditions: Migraine
Interventions: DRUG: Rizatriptan|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Mouthwashes on Oral Wound Healing and Microbiome
Status: COMPLETED
Conditions: Wound Heal|Oral Microbiome
Interventions: OTHER: cetylpyridinium chloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Sub Occipital Muscle Inhibition Technique on Hamstring Flexibility in Post-laminectomy Patients.
Status: RECRUITING
Conditions: Hamstring Tightness
Interventions: OTHER: Sub-occipital muscle inhibition technique|OTHER: conventional therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: FOLFOXIRI for Neoadjuvant Treatment of High-risk Locally Advanced Colorectal Cancer
Status: UNKNOWN
Conditions: High-risk Locally Advanced Colorectal Cancer|Neoadjuvant Chemotherapy|FOLFOXIRI Regimen
Interventions: DRUG: Oxaliplatin|DRUG: Irinotecan|DRUG: Folinic Acid|DRUG: 5FU|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Baseline Cortical Haemodynamics in MS
Status: UNKNOWN
Conditions: Multiple Sclerosis
Interventions: DEVICE: Magnetic Resonance Imaging|DRUG: Prohance (Gadoteridol)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Repetitive Transcranial Magnetic Stimulation in Symptoms of Attention Deficit Hyperactivity Disorder and Cognitive Function In Cocaine Addicts
Status: UNKNOWN
Conditions: Cognition Disorders|Cocaine Dependence|ADHD
Interventions: OTHER: repetitive Transcranial Magnetic Stimulation (rTMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lung Protection in ARDS Using Neurally Adjusted Ventilatory Assist
Status: UNKNOWN
Conditions: ARDS, Human|Mechanical Ventilation Pressure High
Interventions: DEVICE: Neurally adjusted ventilatory assist
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of Recombinant Human Erythropoietin in Anemic Cancer Patients Undergoing Chemotherapy
Status: COMPLETED
Conditions: Chemotherapy Induced Anemia
Interventions: DRUG: recombinant human erythropoietin|DRUG: recombinant human erythropoietin placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: EF5 in Detecting Oxygen Level and Blood Vessels in Tumor Cells of Patients Undergoing Photodynamic Therapy for Intraperitoneal or Pleural Cancer
Status: TERMINATED
Conditions: Advanced Malignant Mesothelioma|Localized Malignant Mesothelioma|Malignant Ascites|Primary Peritoneal Cavity Cancer|Recurrent Malignant Mesothelioma
Interventions: DRUG: etanidazole|PROCEDURE: therapeutic conventional surgery|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Optimizing the Therapeutic Dose of Apatinib Mesylate Tablets in Patients With Lung Cancer by Dose Titration：A Real World Exploratory Study
Status: UNKNOWN
Conditions: NSCLC Stage IV|NSCLC Stage IIIB
Interventions: OTHER: Intervention/treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility Study of Intraoperative Detection of Residual Cancer in Breast Cancer Patients
Status: TERMINATED
Conditions: Breast Cancer|Neoadjuvant Therapy
Interventions: COMBINATION_PRODUCT: Study Device Arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Effects of Exercise on Energy Intake-Prescription of Resistance Exercise
Status: COMPLETED
Conditions: Eating Behavior|Food Reward
Interventions: OTHER: short inter-set rest resistance exercise|OTHER: medium inter-set rest|OTHER: long inter-set rest|OTHER: medium inter-set rest with failure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High Intensity Laser Therapy in the Treatment of Hemiplegic Shoulder Pain
Status: UNKNOWN
Conditions: Shoulder Pain|Hemiplegia|Arthralgia|Joint Diseases|Musculoskeletal Diseases
Interventions: DEVICE: High intensity laser therapy|OTHER: Therapeutic Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: OV Precision: Study Examining the Benefit of a Tumor- and Patient-specific Cancer Therapy
Status: NOT_YET_RECRUITING
Conditions: Ovarian Neoplasm Epithelial|Fallopian Tube Neoplasms|Ovarian Endometrioid Carcinoma|High-grade Serous Ovarian Carcinoma (HGSOC)
Interventions: OTHER: Treatment recommendation by molecular tumorboard (mTB) based on tumor profiling|DRUG: Carboplatin / Paclitaxel Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Antimicrobial Soft Silicone, Silver Containing, Foam Dressing, Mepilex Border Ag, in Second Degree Burns
Status: COMPLETED
Conditions: Burns
Interventions: DEVICE: Mepilex Border Ag
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Safety, Pharmacodynamics and Efficacy of ANB-002 in Patients With Hemophilia B (SAFRAN)
Status: RECRUITING
Conditions: Hemophilia B
Interventions: GENETIC: ANB-002, dose 1|GENETIC: ANB-002, dose 2
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Outcomes of Transrenal Artery Perfusion Versus Transrenal Vein Perfusion Using LifePort for Deceased Donor Kidney Transplantation
Status: COMPLETED
Conditions: Kidney Transplantation|Organ Preservation
Interventions: DEVICE: LifePort transrenal artery perfusion|DEVICE: LifePort transrenal vein perfusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Comparison Between High-density Electroencephalography and Conventional Electroencephalography for Comatose Patients
Status: TERMINATED
Conditions: Post Anoxic Coma
Interventions: DEVICE: high-density electroencephalography|DEVICE: Conventional electroencephalography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Measuring Stress in Women With Newly Diagnosed Stage I, Stage II, or Stage III Breast Cancer or Ductal Carcinoma In Situ of the Breast
Status: COMPLETED
Conditions: Anxiety Disorder|Breast Cancer|Depression|Psychosocial Effects of Cancer and Its Treatment
Interventions: OTHER: laboratory biomarker analysis|OTHER: questionnaire administration|OTHER: study of socioeconomic and demographic variables|PROCEDURE: assessment of therapy complications|PROCEDURE: psychosocial assessment and care|PROCEDURE: therapeutic conventional surgery
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: An Open-label, Phase I/II Study of PLENA Regimen in Patients With Unresectable Pancreatic Cancer or BTC
Status: UNKNOWN
Conditions: Pancreatic Cancer|Biliary Tract Cancer
Interventions: DRUG: Durvalumab|DRUG: Lenvatinib|DRUG: Nab paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic, Efficacy and Safety of BT524 in Patients With Congenital Fibrinogen Deficiency
Status: COMPLETED
Conditions: Congenital Afibrinogenemia|Congenital Hypofibrinogenemia
Interventions: BIOLOGICAL: BT524 (fibrinogen concentrate from human plasma)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Follow-up Assessment of Resistance to ABT-333 in Hepatitis C Virus (HCV)-Infected Subjects Who Have Received ABT-333 in ABT-333 Studies
Status: COMPLETED
Conditions: HCV Infection
Interventions: PROCEDURE: Blood sample collection only|DRUG: ABT-333
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Effects of Core Strengthening and PNF Pattern on Balance and Plantar Pressure in Chronic Stroke
Status: UNKNOWN
Conditions: Stroke; Paralysis
Interventions: OTHER: core strengthening exercises|OTHER: Routine physical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Preliminary Assessment of Safety and Tolerability of Dostarlimab in Combination Antiretroviral Therapy (cART) Refractory HIV Associated Kaposi Sarcoma
Status: RECRUITING
Conditions: Refractory HIV Associated Kaposi Sarcoma
Interventions: DRUG: Dostarlimab in Combination Antiretroviral Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Individualization of Dosage of Irinotecan in the FOLFIRI According to the Genetic Polymorphism of UGT1A1 in the First Line Treatment of Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: First Line Metastatic Colorectal Cancer
Interventions: DRUG: Irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exploring the Role of Online Discussion Forums in Internet-Delivered Therapy for Canadian Public Safety Personnel
Status: COMPLETED
Conditions: Depression|Anxiety|Stress Disorders, Post-Traumatic
Interventions: BEHAVIORAL: The Self-Guided PSP Wellbeing Course|BEHAVIORAL: Online Discussion Forum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Effect of Ketoconazole on the Pharmacokinetics of Abiraterone Following Administration of Abiraterone Acetate Tablets in Healthy Adult Men
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Period 1: Abiraterone|DRUG: Period 2: Abiraterone/Ketoconazole|DRUG: Period 2: Abiraterone/Ketoconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of ABT-493/ABT-530 in Adults With Chronic Hepatitis C Virus (HCV) Genotype 2 Infection
Status: COMPLETED
Conditions: Chronic Hepatitis C Virus (HCV) Infection
Interventions: DRUG: ABT-493/ABT-530|DRUG: Placebo for ABT-493/ABT-530
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of The Efficacy And Safety of Intra-Articular Etanercept in Patients With Refractory Knee Joint Synovitis
Status: COMPLETED
Conditions: Persistent Knee Joint Synovitis
Interventions: DRUG: etanercept|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effects of Manipulative Therapy and Pain Education in Individuals With CLBP
Status: COMPLETED
Conditions: Low Back Pain
Interventions: OTHER: Manipulative Therapy|OTHER: Pain Education|OTHER: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Postpartum Depression With Psychotherapy and Add-on Sertraline
Status: COMPLETED
Conditions: Postpartum Depression
Interventions: DRUG: Sertraline|DRUG: placebo|OTHER: psychotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of NT Vs Body Weight Supported TT Along With CT on Lower Extremity in Chronic Stroke Patients
Status: COMPLETED
Conditions: Chronic Stroke
Interventions: DIAGNOSTIC_TEST: Neurodevelopmental Treatment|DIAGNOSTIC_TEST: Body weight supported treadmill training along with conventional therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: An Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics Study of JNJ-17299425 in Participants With Traumatic Brain Injury
Status: TERMINATED
Conditions: Traumatic Brain Injury
Interventions: DRUG: JNJ-17299425
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of Transcranial Direct Current Stimulation as Adjunctive Treatment for Chronic Daily Headache in Systemic Lupus Erythematosus
Status: NOT_YET_RECRUITING
Conditions: Systemic Lupus Erythematosus|Chronic Headache
Interventions: DEVICE: Transcranial Direct Current Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Caloric Restriction on Fat Oxidation in Obese Men and Women (Magellan II)
Status: COMPLETED
Conditions: Obesity|Overweight|Metabolic Diseases
Interventions: BEHAVIORAL: Low Calorie Diet (LCD)|DRUG: Phentermine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Phase I Study of ZN-c3 and Bevacizumab ± Pembrolizumab in Metastatic CCNE1 Amplified and TP53 Mutant Solid Tumors
Status: WITHDRAWN
Conditions: Tumors|Ovarian Cancer|Breast Cancer|Lung Cancer|Pancreatic Cancer
Interventions: DRUG: ZN-c3|DRUG: Bevacizumab|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate Efficacy and Safety With LEO 90100 Compared With Daivobet® Ointment in Adult Chinese Subjects With Stable Plaque Psoriasis
Status: COMPLETED
Conditions: Stable Plaque Psoriasis
Interventions: DRUG: LEO 90100|DRUG: Daivobet® ointment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating the Effect of IMA-026 on Allergen-Induced Late Asthma Response in Mild Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: IMA-026|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Excitatory Amino Acids and Activated Microglia After Traumatic Brain Injury: a (R)-[11C]PK11195 PET Study
Status: UNKNOWN
Conditions: Traumatic Brain Injury
Interventions: DEVICE: Positron Emission Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Development and Validation of a Smart Phone Based System to Enhance Gait, Cognition and Socialization in Elderly Fallers
Status: UNKNOWN
Conditions: Older Adults
Interventions: DEVICE: Monitoring and training using the system|BEHAVIORAL: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of SHR-1210 Versus Investigator's Choice of Chemotherapy for Participants With Advanced Esophageal Cancer
Status: COMPLETED
Conditions: Esophageal Carcinoma
Interventions: BIOLOGICAL: camrelizumab|DRUG: Docetaxel|DRUG: Irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of a Percussion Device to Mobilise Sputum From Respiratory Passage
Status: COMPLETED
Conditions: Chronic Bronchiectasis|Chronic Obstructive Pulmonary Disease (COPD)
Interventions: PROCEDURE: Conventional Chest Physiotherapy (CCPT)|DEVICE: Mechanical percussion (LEGA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Safety and Efficacy on New Peritoneal Dialysis Solutions
Status: WITHDRAWN
Conditions: End-Stage Renal Disease
Interventions: DRUG: PD solution for nocturnal exchanges|DRUG: PD solution for diurnal exchanges
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Extension Study (Extended Access) of Syk-inhibition Using Fostamatinib to Treat Posttransplant Immune-mediated Cytopenias
Status: ENROLLING_BY_INVITATION
Conditions: Immune Mediated Anemia|Immune Mediated Thrombocytopenia|Chronic GVHD
Interventions: DRUG: fostamatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety, Tolerability, and Immunogenicity of V114 in Children With Sickle Cell Disease (V114-023/PNEU-SICKLE)
Status: COMPLETED
Conditions: Pneumococcal Infections
Interventions: BIOLOGICAL: V114|BIOLOGICAL: Prevnar 13™
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Study With CY, Pembrolizumab, GVAX Pancreas Vaccine, and SBRT in Patients With Locally Advanced Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DRUG: Cyclophosphamide|DRUG: GVAX Pancreatic Cancer Vaccine|DRUG: Pembrolizumab|RADIATION: SBRT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Bone Preservation When OsseoSpeed™ Implants Are Placed Immediately Following Tooth Extraction
Status: COMPLETED
Conditions: Jaw, Edentulous, Partially
Interventions: DEVICE: OsseoSpeed™|DEVICE: OsseoSpeed™
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Glycemic Response of Sorghum
Status: COMPLETED
Conditions: Blood Glucose
Interventions: OTHER: Glycemic response of F-1000|OTHER: Glycemic response to sumac sorghum flour|OTHER: Glycemic response to MMR sorghum flour|OTHER: Glycemic response to wheat flour|OTHER: Glycemic response to sucrose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Safety and Immunogenicity Study of a DNA Vaccine Combined With Protein Vaccine Against HIV/AIDS
Status: COMPLETED
Conditions: HIV/AIDS
Interventions: BIOLOGICAL: DNA|BIOLOGICAL: AIDSVAX B/E
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Enhancing Cognitive Reserve of the Offsprings of Bipolar and Schizophrenic Patients
Status: UNKNOWN
Conditions: Bipolar and Related Disorders
Interventions: BEHAVIORAL: Enhancing Cognitive Reserve|BEHAVIORAL: Support intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Safety of TZP-101 (IV Ulimorelin) Administered Post-Operatively in Patients Who Have Undergone Partial Bowel Resection
Status: COMPLETED
Conditions: Postoperative Ileus
Interventions: DRUG: TZP-101|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Residual Antimicrobial Efficacy of One Test Material Based on a Modification of ASTM E1115-11 Test Method
Status: COMPLETED
Conditions: Hand Hygiene
Interventions: DRUG: Chlorhexidine Gluconate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Early Usage of Bakri Ballon in Managing Postpartum Hemorrhage
Status: COMPLETED
Conditions: Postpartum Hemorrhage
Interventions: DEVICE: Bakri Balloon|DRUG: Oxytocin|DRUG: Hemabate|DRUG: Duratocin|PROCEDURE: Uterine Massage|PROCEDURE: B-lynch Suture|PROCEDURE: Uterine Artery Embolization using sponges|PROCEDURE: Cervical cerclage|PROCEDURE: Hysterectomy|DRUG: Blood Product
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lifestyle Program (Scalable Nutrition and Physical Activity) for the Improvement of Nutrition and Physical Activity in Stage 0-III Breast Cancer Survivors
Status: COMPLETED
Conditions: Anatomic Stage 0 Breast Cancer AJCC v8|Anatomic Stage I Breast Cancer AJCC v8|Anatomic Stage IA Breast Cancer AJCC v8|Anatomic Stage IB Breast Cancer AJCC v8|Anatomic Stage II Breast Cancer AJCC v8|Anatomic Stage IIA Breast Cancer AJCC v8|Anatomic Stage IIB Breast Cancer AJCC v8|Anatomic Stage III Breast Cancer AJCC v8|Anatomic Stage IIIA Breast Cancer AJCC v8|Anatomic Stage IIIB Breast Cancer AJCC v8|Anatomic Stage IIIC Breast Cancer AJCC v8|Prognostic Stage 0 Breast Cancer AJCC v8|Prognostic Stage I Breast Cancer AJCC v8|Prognostic Stage IA Breast Cancer AJCC v8|Prognostic Stage IB Breast Cancer AJCC v8|Prognostic Stage II Breast Cancer AJCC v8|Prognostic Stage IIA Breast Cancer AJCC v8|Prognostic Stage IIB Breast Cancer AJCC v8|Prognostic Stage III Breast Cancer AJCC v8|Prognostic Stage IIIA Breast Cancer AJCC v8|Prognostic Stage IIIB Breast Cancer AJCC v8|Prognostic Stage IIIC Breast Cancer AJCC v8
Interventions: BEHAVIORAL: One Diet and Physical Activity Session|OTHER: Electronic (e) Health (eHealth) Communication Intervention|BEHAVIORAL: Twelve Diet and Physical Activity Group Sessions|OTHER: Questionnaire Administration|OTHER: Quality-of-Life Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Nutrition in Gastrointestinal Tumors
Status: COMPLETED
Conditions: Pancreatic Cancer|Oesophageal Cancer|Colon Cancer|Liver Cancer|Rectal Cancer|Bile Duct Cancer|GIST, Malignant|Neuroendocrine Tumors|Small Intestine Cancer|Gastric Cancer
Interventions: OTHER: No intervention - observational study only
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study to Evaluate Efficacy and Safety of Selective Internal Radiation Therapy Plus Xelox, Bevacizumab and Atezolizumab (Immune Chekpoint Inhibitor) in Patients With Liver-dominant Metastatic Colorectal Cancer
Status: RECRUITING
Conditions: Metastatic Colorectal Cancer|pMMR|MSS|Immune Checkpoint Inhibitor|Internal Radiotherapy
Interventions: DRUG: Atezolizumab|DEVICE: Therasphere|DRUG: XELOX|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Breathe for Hot Flashes Randomized Controlled Trial
Status: COMPLETED
Conditions: Hot Flashes
Interventions: BEHAVIORAL: Paced respiration|BEHAVIORAL: Sham comparator: fast shallow breathing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE