pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Validation Study of Coronary CT Angiography as a Screening Tool in Asymptomatic Diabetes
Status: COMPLETED
Conditions: Coronary Atherosclerosis|Diabetes Mellitus
Interventions: PROCEDURE: coronary computed tomography angiography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Influence of Fampridine on Working Memory in Individuals With Post COVID-19 Condition With Subjective Cognitive Impairment
Status: TERMINATED
Conditions: Working Memory|Post-covid-19
Interventions: DRUG: Fampridine SR|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Evaluation of Nitric Oxide Generating Lozenges on Outcome in Newly Diagnosed COVID-19 Patient of African American and Hispanic Origin
Status: TERMINATED
Conditions: COVID-19
Interventions: DRUG: Nitric Oxide lozenges, 30 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: SARC038: Phase 2 Study of Regorafenib and Nivolumab in Osteosarcoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Osteosarcoma|Osteosarcoma in Children|Osteosarcoma Recurrent|Osteosarcoma Metastatic
Interventions: DRUG: Regorafenib 40 MG|DRUG: Regorafenib 20MG|DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Personalized Atrial Fibrillation Ablation With QDOT
Status: RECRUITING
Conditions: Atrial Fibrillation
Interventions: DEVICE: Atrial fibrillation ablation using the QDOT® catheter|PROCEDURE: Standard atrial fibrillation ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of Combining Physical Exercise and Cognitive Training for Individuals With Mild Cognitive Impairment
Status: UNKNOWN
Conditions: Mild Cognitive Impairment
Interventions: BEHAVIORAL: Sequential training
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Immune Response to a Recombinant Adenovirus HIV-1 Vaccine in Healthy Adults
Status: COMPLETED
Conditions: HIV Infections
Interventions: BIOLOGICAL: Ad5.ENVA.48 HIV-1 vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Impact of a Prehospital Identification of Trauma Patients in Need for Damage Control Resuscitation.
Status: UNKNOWN
Conditions: Trauma|Coagulopathy|Hemorrhage|Emergencies
Interventions: DIAGNOSTIC_TEST: Use of the Trauma Induced Coagulopathy Clinical Score (TICCS) as a diagnostic tool.|DIAGNOSTIC_TEST: Regular care|OTHER: STTTOPPP the bleeding|OTHER: Regular Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Regional Distribution of Ventilation at Different Respiratory Rates
Status: RECRUITING
Conditions: Mechanical Ventilation|Atelectasis|Distribution of Ventilation
Interventions: DEVICE: Ventilation 20-40-60|DEVICE: Ventilation 60-40-20|DEVICE: Ventilation 40-60-20
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of OroPharyngeal Exercises on Patients With Moderate Obstructive Sleep Apnea
Status: COMPLETED
Conditions: Obstructive Sleep Apnea
Interventions: BEHAVIORAL: Deep breathing, bilateral alternate chewing, nasal lavage|BEHAVIORAL: Oropharyngeal exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: IX001 TCR-T In the Treatment of Advanced Pancreatic Cancer and Colorectal Cancer Induced by KRAS Mutations
Status: RECRUITING
Conditions: Pancreatic Cancer|Colorectal Cancer
Interventions: BIOLOGICAL: IX001 TCR-T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study for Treatment of Pain in Patients With Diabetic Neuropathy.
Status: COMPLETED
Conditions: Diabetic Neuropathy, Painful
Interventions: DRUG: Placebo|DRUG: Pregabalin|DRUG: LY545694 21 mg|DRUG: LY545694 49 mg|DRUG: LY545694 105 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Open Study to Evaluate Whether Pack Size Affects Compliance of Metformin Treatment in Subjects With Type II Diabetes
Status: TERMINATED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Metformin Small Pack|DRUG: Metformin Large Pack
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Foot and Ankle Clinic Application for Liposomal Related Anesthetic
Status: COMPLETED
Conditions: Ankle Arthrodesis|Hindfoot Arthrodesis|Tibitalocalceal Arthrodesis
Interventions: DRUG: Exparel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Topical Liposomal Form of Drugs in Cutaneous Leishmaniasis
Status: COMPLETED
Conditions: Cutaneous Leishmaniasis
Interventions: DRUG: Liposomal meglumine antimoniate (Glucantime)|DRUG: Liposomal meglumine antimoniate|DRUG: Liposomal Paromomycin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: This Study Aim is to Compare the Effect of Oral Methyl Prednisolone on Different Radiological Patterns of Hypersensitivity Pneumonitis as it Was Found That Not All Patients Get Satisfying Therapeutic Effect After Taking Corticosteroids.
Status: UNKNOWN
Conditions: Hypersensitivity Pneumonitis
Interventions: DRUG: Methyl Prednisolonate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Balneotherapy With Acquabios Thermal Water in Knee Osteoarthritis
Status: UNKNOWN
Conditions: Knee Osteoarthritis
Interventions: OTHER: Balneotherapy with thermal water|OTHER: Balneotherapy with tap water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Local Heat Therapy Versus Sodium Stibogluconate for the Treatment of Cutaneous Leishmaniasis
Status: COMPLETED
Conditions: Cutaneous Leishmaniasis
Interventions: DRUG: Sodium stibogluconate (Pentostam)|DEVICE: ThermoMed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Febuxostat Compared to Placebo on Exercise Tolerance in Participants With Chronic Stable Angina
Status: TERMINATED
Conditions: Angina
Interventions: DRUG: Febuxostat|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use of the Nine Holes Peg Test in Multiple Sclerosis: Participation of Elementary Neurological Components in the Functional Evaluation of Manual Dexterity
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DIAGNOSTIC_TEST: Scale for the assessment and rating of ataxia (SARA)|DEVICE: JAMAR hand dynamometer|DEVICE: Vibratory sensibility testing|DEVICE: Sermes and Weinstein test|DEVICE: Weber test
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: ACTIV-6: COVID-19 Study of Repurposed Medications - Arm F (Montelukast)
Status: COMPLETED
Conditions: Covid19
Interventions: OTHER: Placebo|DRUG: Montelukast
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Use of Ketorolac in Management of Post-Operative Pain After Heart Surgery
Status: COMPLETED
Conditions: Pain Management Following Cardiopulmonary Bypass Surgery
Interventions: DRUG: Ketorolac|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pramipexole as a Treatment for Cocaine Dependence
Status: COMPLETED
Conditions: Cocaine Addiction|Cocaine Abuse|Cocaine Dependence|Substance Abuse
Interventions: DRUG: Pramipexole|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Study to Evaluate Safety, Tolerability, Pharmacokinetics & Pharmacodynamics of JTT-662 in Subjects With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: JTT-662|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Compare the Efficacy and Safety of Ponesimod to Placebo in Subjects With Active Relapsing Multiple Sclerosis Who Are Treated With Dimethyl Fumarate (Tecfidera®)
Status: TERMINATED
Conditions: Multiple Sclerosis
Interventions: DRUG: Ponesimod|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics and Safety of BI 1744 CL Plus Tiotropium Bromide in Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: BI 1744 CL|DRUG: BI 1744 CL/Tiotropium FDC|DRUG: Tiotropium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Pembrolizumab Plus Paclitaxel, Cisplatin Followed by Surgery for Locally Advanced ESCC (KEYSTONE-001)
Status: ACTIVE_NOT_RECRUITING
Conditions: Esophageal Squamous Cell Carcinoma|Stage III
Interventions: DRUG: Pembrolizumab Injection [Keytruda]
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Clinical Performance and Safety of Zirconia vs. Titanium Implants: a Multi-national RCT.
Status: ACTIVE_NOT_RECRUITING
Conditions: Dental Implants, Single-Tooth
Interventions: DEVICE: Ceramic Dental Implant|DEVICE: Titanium Dental Implant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Improving Diagnostic and Communication Skills on Antibiotic Prescribing Appropriateness in Acute Cough
Status: UNKNOWN
Conditions: Respiratory Tract Infections|Cough
Interventions: DIAGNOSTIC_TEST: C-reactive protein rapid testing|PROCEDURE: Communication skill enhancement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Open and Minimally Invasive Surgical Techniques in the Treatment of Degenerative One-level Stenosis of Lumbar Spine
Status: TERMINATED
Conditions: Spinal Stenosis Lumbar Canal With Neurogenic Claudication (Diagnosis)
Interventions: PROCEDURE: Decompression|PROCEDURE: PLIF|PROCEDURE: MIS TLIF|PROCEDURE: Screw Fixation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Reminder App to Reduce Radiation Dermatitis Rates in Patients With Head-and-Neck Cancer
Status: UNKNOWN
Conditions: Radiation Dermatitis|Radiation-induced Oral Mucositis
Interventions: DEVICE: mobile application (reminder app)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of Capecitabine (Xeloda®) and Concomitant Radiation Therapy in Children With Newly Diagnosed Brainstem Gliomas
Status: COMPLETED
Conditions: Brainstem Glioma
Interventions: DRUG: Capecitabine|RADIATION: Radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Drug-drug Interaction Study Between Lopinavir/Ritonavir and Isavuconazole
Status: COMPLETED
Conditions: Pharmacokinetics of Isavuconazole|Pharmacokinetics of Lopinavir/Ritonavir|Healthy Volunteers
Interventions: DRUG: Isavuconazole|DRUG: Lopinavir/ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Safety and Immunogenicity of Live Attenuated Varicella Vaccine in Healthy Population Aged ≥13 Years Old
Status: COMPLETED
Conditions: Varicella
Interventions: BIOLOGICAL: Live attenuated varicella vaccines manufactured by Shanghai Institute of Biological Products Co.,Ltd.|BIOLOGICAL: Live attenuated varicella vaccines manufactured by Changchun BCHT Biotechnology Co.,Ltd
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Head-up Tilt Sleeping to Alleviate Orthostatic Hypotension, Supine Hypertension and Nocturia in Parkinson's Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Parkinson Disease|Parkinsonism
Interventions: OTHER: Head-up tilt sleeping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: beCLomethasone Efficacy in Acute Rhinosinusitis - CLEAR Study
Status: COMPLETED
Conditions: Acute Rhinosinusitis
Interventions: DRUG: beclomethasone dipropionate 800 mcg/2 ml suspension for nebulization,one administration b.i.d. for 14 days|DRUG: placebo 2 ml suspension for nebulization, one administration b.i.d. for 14 days
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Analgesic Efficacy of Serratus Posterior Superior Intercostal Plane (SPSIP) Block in Shoulder Arthroscopies
Status: RECRUITING
Conditions: Pain, Postoperative|Shoulder Pain|Block
Interventions: PROCEDURE: Serratus Posterior Superior Intercostal Plane Block|DEVICE: patient controlled analgesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pre-market, Multi-center, International, Double-blind, Randomized, Two-arms, Controlled, Prospective Clinical Investigation Assessing the Safety and Performance of a Medical Device (ClearPlasma™) for the Treatment of Patients Undergoing Coronary Artery Bypass or Valve Replacement
Status: RECRUITING
Conditions: Bleeding|Bypass Complication|Valve Replacement
Interventions: DEVICE: ClearPlasma
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Fascia Iliaca Block in Hip Fracture Patients
Status: COMPLETED
Conditions: Hip Fractures (i.e. Femoral Neck or Intertrochanteric Hip Fractures)
Interventions: PROCEDURE: Fascia iliaca block arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Ultrasonographic Guided Insulin Injection With Dexamethasone and Local Anesthetic Mixture in Diabetic Patients With Mild to Moderate Carpal Tunnel .
Status: UNKNOWN
Conditions: Pain Relief
Interventions: DRUG: insulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Lutonix Drug Coated Balloon for Treatment of Femoropopliteal Arteries in United States Females (CONFIRM)
Status: TERMINATED
Conditions: Femoral Artery Stenosis|Popliteal Artery Stenosis|Femoral Artery Occlusion|Popliteal Artery Occlusion
Interventions: DEVICE: Lutonix® 035 Drug Coated Balloon PTA Catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Arousal Response Tool for Neurological Disease
Status: UNKNOWN
Conditions: Parkinson Disease|Stroke|Healthy
Interventions: DEVICE: MS Band 2|BEHAVIORAL: Emotion Assessment|BEHAVIORAL: Single Task|BEHAVIORAL: Dual Task|BEHAVIORAL: Rest
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Vibrotactile Coordinated Reset in Parkinson's Disease - Proof of Concept Study
Status: NOT_YET_RECRUITING
Conditions: Parkinson Disease
Interventions: DEVICE: Stanford Glove
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of LVGN6051 Combination Therapy in Patient With Head and Neck Squamous Cell Carcinoma (HNSCC)
Status: RECRUITING
Conditions: Head and Neck Squamous Cell Carcinoma
Interventions: BIOLOGICAL: LVGN6051 Monoclonal Antibody Injection|BIOLOGICAL: toripalimab Injection|DRUG: Paclitaxel injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non-invasive Imaging Technique for the Study of Lordosis in Pregnant Women and Its Relationship to Birth Outcome
Status: RECRUITING
Conditions: Pregnancy Outcome|Biomechanics|Back Disorder|Diagnostic Imaging|Biomedical Technology
Interventions: DIAGNOSTIC_TEST: Arrow Test|DIAGNOSTIC_TEST: Angle measurement by imaging device
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Influences of Propofol and Sevoflurane Anesthesia in Brain Tumor
Status: RECRUITING
Conditions: Brain Tumor
Interventions: DRUG: Propofol|DRUG: Sevoflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Effect of Physiotherapy Protocol in Treatment of Depression: Longitudinal Study
Status: NOT_YET_RECRUITING
Conditions: Fibromyalgia|Depression
Interventions: OTHER: Physiotherapy protocol|DRUG: Selective serotonin reuptake inhibitors (SSRI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of TAK-954 on Gastrointestinal and Colonic Transit in Diabetic or Idiopathic Gastroparesis Participants
Status: COMPLETED
Conditions: Diabetic Gastroparesis|Idiopathic Gastroparesis
Interventions: DRUG: TAK-954|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Exercise Therapy and Patient Education for Individuals With Hip Osteoarthritis. Long-term Follow-up.
Status: UNKNOWN
Conditions: Hip Osteoarthritis
Interventions: OTHER: A 12 week exercise therapy program and patient education.|OTHER: Patient education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Four Combination Chemotherapy Regimens Using Cisplatin in Treating Patients With Stage IVB, Recurrent, or Persistent Cancer of the Cervix
Status: COMPLETED
Conditions: Cervical Adenocarcinoma|Cervical Adenosquamous Carcinoma|Cervical Squamous Cell Carcinoma|Recurrent Cervical Carcinoma|Stage IVB Cervical Cancer
Interventions: DRUG: Cisplatin|DRUG: Gemcitabine Hydrochloride|DRUG: Paclitaxel|OTHER: Quality-of-Life Assessment|DRUG: Topotecan Hydrochloride|DRUG: Vinorelbine Tartrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Inflammation REduction to Prevent cArdiovascular Injury in Renal Disease (REPAIR)
Status: NOT_YET_RECRUITING
Conditions: Chronic Kidney Diseases|Renal Failure
Interventions: DRUG: Colchicine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Macrophage Polarization in Response to Macronutrient Intake in Healthy Humans: A Randomized Clinical Study
Status: COMPLETED
Conditions: Atherosclerosis
Interventions: DIETARY_SUPPLEMENT: Lipid Intake|DIETARY_SUPPLEMENT: Glucose intake|DIETARY_SUPPLEMENT: Protein intake
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Clinic Waiting Room-based Study of Swahili Language Artificial Intelligence-driven Symptom Assessments in Tanzanian Primary Health Care Facilities
Status: UNKNOWN
Conditions: Abdominal Pain/Gastrointestinal Issues|Lower Respiratory System Conditions|Upper Respiratory System Conditions|Mental Health Conditions|Ophthalmology Conditions|Orthopedic Conditions|Cardiovascular System Conditions|Genitourinary System Conditions|ENT Conditions|Dermatology Conditions|Gynecology/Obstetrics Conditions|Neurological Conditions
Interventions: DEVICE: Ada Waiting Room App (WRA) and Ada Diagnostic Support Application (HDA)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical Trial of Bilhvax,a Vaccine Candidate Against Schistosomiasis
Status: COMPLETED
Conditions: Schistosomiasis|Bilharziasis|Urinary Schistosomiasis
Interventions: BIOLOGICAL: rSh28GST
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Study on the Efficacy and Safety of Chiglitazar Sodium in PCOS With T2DM
Status: ENROLLING_BY_INVITATION
Conditions: PCOS (Polycystic Ovary Syndrome) of Bilateral Ovaries|T2D
Interventions: DRUG: pioglitazone group: lifestyle intervention+ metformin+ orlistat (obese patients)+ pioglitazone|DRUG: the Chiglitazar group: lifestyle intervention+ metformin+ orlistat (obese patients)+ Chiglitazar
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cookstove Replacement for Prevention of ALRI and Low Birthweight in Nepal
Status: COMPLETED
Conditions: Acute Lower Respiratory Illness
Interventions: OTHER: Improved biomass cookstove with exterior ventilation|OTHER: Phase 2 intervention arm (LPG stove)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Intra-Arterial Chemotherapy for Newly Diagnosed, Residual, or Recurrent Atypical Choroid Plexus Papilloma and Choroid Plexus Carcinoma Prior to Second-Look Surgery
Status: RECRUITING
Conditions: Atypical Choroid Plexus Papilloma|Choroid Plexus Carcinoma
Interventions: DRUG: Melphalan|DRUG: Carboplatin|DRUG: Topotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Melphalan, Total Marrow Irradiation, and Autologous Stem Cell Transplantation in Treating Patients With High-Risk Multiple Myeloma
Status: WITHDRAWN
Conditions: Plasma Cell Leukemia in Remission|Plasma Cell Myeloma
Interventions: PROCEDURE: Autologous Hematopoietic Stem Cell Transplantation|DRUG: Cyclophosphamide|BIOLOGICAL: Filgrastim|OTHER: Laboratory Biomarker Analysis|DRUG: Lenalidomide|PROCEDURE: pheresis|DRUG: Melphalan|BIOLOGICAL: Palifermin|RADIATION: Total Marrow Irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CD19-Directed CAR-T Cell Therapy for the Treatment of Relapsed/Refractory B Cell Malignancies
Status: RECRUITING
Conditions: Recurrent B-Cell Non-Hodgkin Lymphoma|Recurrent Chronic Lymphocytic Leukemia|Recurrent Small Lymphocytic Lymphoma|Recurrent Transformed Chronic Lymphocytic Leukemia|Refractory B-Cell Non-Hodgkin Lymphoma|Refractory Chronic Lymphocytic Leukemia|Refractory Small Lymphocytic Lymphoma|Refractory Transformed Chronic Lymphocytic Leukemia
Interventions: BIOLOGICAL: Autologous Anti-CD19 CAR-expressing T-lymphocytes IC19/1563|DRUG: Bendamustine|PROCEDURE: Biospecimen Collection|PROCEDURE: Bone Marrow Aspiration|PROCEDURE: Bone Marrow Biopsy|PROCEDURE: Computed Tomography|DRUG: Cyclophosphamide|DRUG: Fludarabine|PROCEDURE: Magnetic Resonance Imaging|PROCEDURE: Positron Emission Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EVESOR: a Phase 1 Trial of Everolimus and Sorafenib
Status: UNKNOWN
Conditions: Metastatic or Locally Advanced Solid Tumors
Interventions: DRUG: Everolimus and sorafenib|DRUG: Everolimus and sorafenib|DRUG: Everolimus and sorafenib|DRUG: Everolimus and sorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Genecept Assay™ vs. Treatment-as-Usual to Evaluate Efficacy of Assay-Guided Treatment in Adults With MDD
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: GENETIC: Assay-guided treatment (AGT)|OTHER: Treatment-as-usual (TAU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Safety and Efficacy of OPC-34712 as Adjunctive Therapy in the Treatment of Adults With Major Depressive Disorder
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: OPC-34712|DRUG: Placebo|DRUG: ADT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Longitudinal Study on Glaucoma Surgery Using XEN® Gel Stent
Status: UNKNOWN
Conditions: Glaucoma|Glaucoma, Open-Angle|Glaucoma, Angle-Closure|Glaucoma, Primary Open Angle
Interventions: PROCEDURE: XEN® Gel Stent implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Patient Satisfaction Study of Single-Use Autoinjector for the Delivery of Pre-Filled Avonex Syringe
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DRUG: Interferon beta-1a|DEVICE: Single-use autoinjector
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Impact of Information Strategy Based on Booklet on Anxiety in Family in ICU
Status: UNKNOWN
Conditions: Anxiety|Depression|Post-traumatic Stress Disorders
Interventions: OTHER: booklet deliverance and use in the process of daily information
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Trial of Afatinib (BIBW 2992) + Cetuximab in Advanced Solid Tumours
Status: COMPLETED
Conditions: Neoplasms
Interventions: DRUG: Cetuximab( erbitux®)|DRUG: Afatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Intravenous Lidocaine on Propofol Requirements
Status: COMPLETED
Conditions: Analgesia
Interventions: DRUG: Lidocaine IV|DRUG: 0.9% normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: In-vivo Analysis and Clinical Evaluation of the Performance of a Fractional CO2 Laser System (eMatrixCO2)
Status: COMPLETED
Conditions: Aesthetic Dermatology
Interventions: PROCEDURE: Ablation and skin resurfacing
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Supra-aortic Trunks Debranching Techniques in Open Arch Repair by Means of Frozen Elephant Trunk Procedure With Two Configurations of the Jotec E-Vita Hybrid Graft (FETOPT)
Status: COMPLETED
Conditions: Aneurysms Aortic Arch
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Perioperative Intravenous Lidocaine on Postoperative Quality of Recovery in Patients Undergoing Spine Surgery
Status: WITHDRAWN
Conditions: Pain
Interventions: DRUG: Lidocaine|OTHER: Placebo (normal saline)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prescription Opioid Addiction Treatment Study (POATS)
Status: COMPLETED
Conditions: Opiate Dependence|Substance-related Disorders|Opioid-related Disorders
Interventions: BEHAVIORAL: Standard Medical Management (SMM) of Prescription Opiate Abuse|BEHAVIORAL: Enhanced Medical Management (EMM) of Prescription Opiate Abuse
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Characterization of the Gut Microbiota Composition and Activity After Three Weeks of Chitin-glucan Supplementation
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Chitin-glucan fiber
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Connectomic Targeted TMS Target for Refractory Anxiety
Status: NOT_YET_RECRUITING
Conditions: Anxiety Disorders|Mental Disorder|Psychiatric Disorder
Interventions: PROCEDURE: Transcranial magnetic stimulation|PROCEDURE: Sham transcranial magnetic stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ADVANCE-D: Antitachycardia Pacing (ATP) Delivery for Painless Implantable Cardioverter Defibrillator (ICD) Therapy
Status: COMPLETED
Conditions: Tachycardia, Ventricular|Ventricular Fibrillation
Interventions: DEVICE: Implantable Cardiac Defibrillator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Trial of Acquired Haemophilia With Steroid Combined With Cyclophosphamide Versus Steroid Combined With Rituximab
Status: COMPLETED
Conditions: Acquired Hemophilia A
Interventions: DRUG: Steroid|DRUG: Rituximab|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Paricalcitol in the Reduction of Secondary Hyperparathyroidism After Kidney Transplantation.
Status: COMPLETED
Conditions: Secondary Hyperparathyroidism Due to Renal Causes
Interventions: DRUG: Paricalcitol|DRUG: Calcifediol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Graston Technique in Deep Gluteal Syndrome
Status: COMPLETED
Conditions: Deep Gluteal Syndrome|Piriformis Syndrome
Interventions: DEVICE: Graston|OTHER: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Study of ABT-869 in Combination With Paclitaxel Versus Paclitaxel Alone to Treat Metastatic Breast Cancer
Status: COMPLETED
Conditions: Metastatic Breast Cancer
Interventions: DRUG: ABT-869|DRUG: paclitaxel|DRUG: Placebo for ABT-869
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Airway Inflammation In Patients With Chronic Obstructive Pulmonary Disease
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Salmeterol/fluticasone propionate 50/500mcg Diskus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Study in Participants With Moderate to Severe Psoriasis (UNCOVER-3)
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: Placebo|DRUG: 50 mg etanercept|DRUG: 80 mg ixekizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Anxiety Intervention for Preschool Children With ASD
Status: COMPLETED
Conditions: Anxiety Disorder|Autism Spectrum Disorder
Interventions: BEHAVIORAL: DINO Strategies for Anxiety and fear of Uncertainty Reduction (DINOSAUR)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Digital Therapeutic Lifestyle Intervention Program for Patients With MASLD
Status: NOT_YET_RECRUITING
Conditions: NASH|NASH - Nonalcoholic Steatohepatitis|Liver Diseases
Interventions: OTHER: Noom Weight Application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Manual Treatment on Respiratory Parameters, Pain, Posture and Quality of Life in Chronic Neck Pain
Status: COMPLETED
Conditions: Neck Pain
Interventions: OTHER: cervical|OTHER: thoracic|OTHER: exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multiple Dose Trial Comparing the Plasma Levels of Two Different Analgesic Transdermal Patch Formulations
Status: TERMINATED
Conditions: Healthy
Interventions: DRUG: Patch with centrally acting analgesic|DRUG: Transtec(R) PRO (buprenorphine)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fasting Study of Meloxicam Tablets 15 mg and Mobic® Tablets 15 mg
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Meloxicam Tablets 15 mg|DRUG: Mobic® Tablets 15 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Efficacy of Teacher-delivered Child Mental Healthcare in Primary Schools of India
Status: COMPLETED
Conditions: Child Behavior Disorders
Interventions: BEHAVIORAL: Tealeaf-Mansik Swasta (Tealeaf)|BEHAVIORAL: Enhanced Usual Care (EUC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Embrace TDD: Post-Market Study to Evaluate Intrathecal Morphine as an Alternative to Systemic Opioids for Chronic Pain
Status: COMPLETED
Conditions: Chronic Non-malignant Pain|Chronic Pain|Pain, Back|Pain, Leg
Interventions: DEVICE: Medtronic SynchroMed™ II infusion system|DRUG: Preservative-free morphine sulfate (PFMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Interactive Survivorship Program for the Improvement of Healthcare Resources in Adolescent and Young Adult Cancer Survivors, INSPIRE-AYA Study
Status: RECRUITING
Conditions: Clinical Stage I Cutaneous Melanoma AJCC v8|Clinical Stage II Cutaneous Melanoma AJCC v8|Clinical Stage III Cutaneous Melanoma AJCC v8|Hematopoietic and Lymphoid Cell Neoplasm|Invasive Malignant Neoplasm|Leukemia|Lymphoma|Malignant Solid Neoplasm|Sarcoma|Stage I Colorectal Cancer AJCC v8|Stage II Colorectal Cancer AJCC v8|Stage III Colorectal Cancer AJCC v8|Anatomic Stage I Breast Cancer AJCC v8|Anatomic Stage II Breast Cancer AJCC v8|Anatomic Stage III Breast Cancer AJCC v8|Thyroid Gland Carcinoma
Interventions: OTHER: Internet Mobile Technology|OTHER: Internet-Based Intervention|OTHER: Questionnaire Administration|PROCEDURE: Supportive Care|OTHER: Informational Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Cardiovascular Health Education Program on Community-dwelling Older Adults at Risk of ASCVD
Status: UNKNOWN
Conditions: Cardiovascular Diseases|Healthy Lifestyle|Health Education
Interventions: BEHAVIORAL: HE programme|BEHAVIORAL: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Exploratory Clinical Study to Evaluate the Optimal Dosage of Mosapride and Probiotics in Irritable Bowel Syndrome Without Predominant Diarrhea
Status: COMPLETED
Conditions: Irritable Bowel Syndrome Without Diarrhea
Interventions: DRUG: Probiotics (Medirac)|DRUG: Probiotics (Medirac)|DRUG: Probiotics (Medirac)|DRUG: Probiotics (Medirac)|DRUG: Probiotics (Medirac) placebo/mosapride placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cetuximab in Combination With Anti-PD-1 and mFOLFOX Treat For RAS/BRAF wt Right-Sided Colon Cancer
Status: RECRUITING
Conditions: Colonic Neoplasms
Interventions: COMBINATION_PRODUCT: neoadjuvant chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Side-to-end Anastomosis Versus Colon J Pouch for Reconstruction After Low Anterior Resection for Rectal Cancer (SAVE)
Status: UNKNOWN
Conditions: Rectal Cancer
Interventions: PROCEDURE: side-to-end anastomosis|PROCEDURE: colon j pouch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Metabolic Syndrome and Gen-polymorphs Influence on Weightloss Among Children in Treatment for Overweight
Status: COMPLETED
Conditions: Childhood Obesity|NAFLD (Non-alcoholic Fatty Liver Disease)|Hypertension|Hyperlipidemia|Insulin Sensitivity
Interventions: OTHER: Chronic care multidisciplinary intervention of childhood obesity
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Different Forms of Recovery on the Functionality After Physical Exercise
Status: COMPLETED
Conditions: Massage|Inflammatory Response|Muscle, Skeletal|Cryotherapy Effect|Functional Disturbance
Interventions: OTHER: Foam Roller Recovery|OTHER: Active recovery|OTHER: Immersion in cold water|OTHER: Passive recovery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: AcrySof® IQ ReSTOR® +2.5 D Multifocal Intraocular Lens (IOL) Model SN6AD2 [SV25T0] in Japan
Status: COMPLETED
Conditions: Cataracts
Interventions: DEVICE: AcrySof® IQ ReSTOR® +2.5 D Multifocal IOL Model SN6AD2 [SV25T0]
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Electromyographic Study for the Help and Guidance of BoNTA Administration in the Treatment of Chronic Pelvic Floor Pain
Status: COMPLETED
Conditions: Electromyography|EMG: Myopathy|EMG Syndrome|Pelvic Pain|Pelvic Floor Disorders|Pelvic Pain Syndrome|ElectroPhys: Myopathy
Interventions: DRUG: Clostridium botulinum type A (BoNTA)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dry Powder Inhalation of Cyclosporine A in Lung Transplant Patients With Bronchiolitis Obliterans Syndrome
Status: UNKNOWN
Conditions: Lung Transplantation|Bronchiolitis Obliterans
Interventions: DRUG: Cyclosporine A dry powder inhalation (Drug)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Eliglustat With or Without Imiglucerase in Pediatric Patients With Gaucher Disease (GD) Type 1 and Type 3
Status: ACTIVE_NOT_RECRUITING
Conditions: Gaucher's Disease Type I|Gaucher's Disease Type III
Interventions: DRUG: Eliglustat GZ385660|DRUG: Imiglucerase GZ437843
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dapagliflozin Delays the Loss of Renal Function in Peritoneal Dialysis Patients
Status: RECRUITING
Conditions: Peritoneal Dialysis Complication|Renal Function Aggravated|Sodium-glucose Co-transporter-2 Inhibitors
Interventions: DRUG: Dapagliflozin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of HRS9531 in Healthy Subjects
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: HRS9531|OTHER: placebo|DRUG: HRS9531|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: GM-CSF and Rituximab in Treating Patients With Previously Untreated Follicular Non-Hodgkin Lymphoma
Status: UNKNOWN
Conditions: Lymphoma
Interventions: BIOLOGICAL: rituximab|BIOLOGICAL: sargramostim|GENETIC: gene expression analysis|GENETIC: gene rearrangement analysis|GENETIC: polymerase chain reaction|GENETIC: polymorphism analysis|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Induction of Immunogenicity With Different Doses of Grass MATA in Subjects Allergic to Grass and Rye Pollen
Status: COMPLETED
Conditions: Type I Hypersensitivity
Interventions: BIOLOGICAL: Grass MATA MPL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Safety & Reactogenicity of GSK Biologicals' DTPa/Hib Vaccine When Given at 3, 4 and 5 Months of Age
Status: COMPLETED
Conditions: Tetanus|Haemophilus Influenzae Type b|Acellular Pertussis|Diphtheria
Interventions: BIOLOGICAL: diphtheria, tetanus, pertussis & Hib vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Aveir VR Coverage With Evidence Development Post-Approval Study
Status: RECRUITING
Conditions: Cardiac Pacemaker|Arrythmia|Bradycardia
Interventions: DEVICE: Aveir VR Leadless Pacemaker System|DEVICE: Single-Chamber Transvenous Pacemaker
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Molecular Phenotyping in Predicting Response in Patients With Stage IB-III Esophageal Cancer Receiving Combination Chemotherapy
Status: TERMINATED
Conditions: Stage IB Esophageal Adenocarcinoma|Stage IIA Esophageal Adenocarcinoma|Stage IIB Esophageal Adenocarcinoma|Stage IIIA Esophageal Adenocarcinoma|Stage IIIB Esophageal Adenocarcinoma|Stage IIIC Esophageal Adenocarcinoma
Interventions: DRUG: Paclitaxel|DRUG: Carboplatin|DRUG: Oxaliplatin|DRUG: Leucovorin Calcium|DRUG: Fluorouracil|RADIATION: Radiation Therapy|PROCEDURE: Therapeutic Conventional Surgery|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Quality of Life and Psychosocial Status in Children With Inflammatory Bowel Disease
Status: COMPLETED
Conditions: Inflammatory Bowel Diseases|Psychosocial Impairment
Interventions: DIAGNOSTIC_TEST: Pediatric Quality of Life Inventory (PedsQL)|DIAGNOSTIC_TEST: Strengths and Difficulties Questionnaire (SDQ)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effect of tDCS Combined With Functional Task Training on Motor Recovery in Stroke Patients
Status: UNKNOWN
Conditions: Stroke|Stroke, Acute|Motor Function
Interventions: DEVICE: Repetitive Transcranial Magnetic Stimulation (rTMS)|DEVICE: Transcranial Direct Current Stimulation (tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Triple-arm pH Comparison
Status: COMPLETED
Conditions: In Vitro Fertilisation Outcome
Interventions: OTHER: Transfer embryo from pH 7.20±0.02 on either Day 3 or day 5/6|OTHER: Transfer embryo from pH 7.3±0.02 either Day 3 or day 5/6|OTHER: Transfer embryo from pH of 7.4±0.02 on either Day 3 or day 5/6
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy of 0.12% Chlorhexidine Gluconate for Peri-implant Mucositis and Gingivitis
Status: COMPLETED
Conditions: Mucositis|Gingivitis
Interventions: DRUG: Chlorhexidine gluconate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: FAMS-T1D Self-Regulation and Social Support for T1D
Status: ENROLLING_BY_INVITATION
Conditions: Type 1 Diabetes
Interventions: BEHAVIORAL: FAMS-T1D|BEHAVIORAL: Digital resources for diabetes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Methotrexate Alone Versus Combination of Methotrexate and Subcutaneous Fludarabine for Severe Rheumatoid Arthritis: Safety, Tolerance and Efficacy
Status: COMPLETED
Conditions: Arthritis, Rheumatoid|Synovitis
Interventions: DRUG: Methotrexate|DRUG: Fludarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT