pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Effects of Perioperative Transauricular Vagus Nerve Electrical Stimulation on POD, POCD and CPSP
Status: UNKNOWN
Conditions: Postoperative Cognitive Dysfunction|Postoperative Delirium|Chronic Post Operative Pain
Interventions: DEVICE: transaricular vagus nerve stimulation|DEVICE: fake transaricular vagus nerve stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Modified Pilates Training on Hemodynamic Responses
Status: COMPLETED
Conditions: Cerebral Palsy|Physical Inactivity|Gait Disorders in Children|Gait, Spastic
Interventions: OTHER: exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Basal/Bolus Versus Sliding Scale Insulin In Hospitalized Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes|Hyperglycemia
Interventions: DRUG: sliding scale regular insulin|DRUG: glargine basal insulin and glulisine prandial insulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cereset Research For Chronic Nausea
Status: WITHDRAWN
Conditions: Nausea|Gastroparesis|Stress|Anxiety|Hyperarousal|Quality of Life|Vomiting|Heart Rate Variability
Interventions: DEVICE: Cereset Research
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Investigation of PICOPREP and PEG-ELS for Bowel Preparation for Colonoscopy
Status: COMPLETED
Conditions: Colonoscopy
Interventions: DRUG: PICOPREP|DRUG: PEG-ELS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Different Stimuli Were Given to Patients With Chronic Pure Tone Tinnitus to Verify the Effective Treatment of Tinnitus.
Status: UNKNOWN
Conditions: Tinnitus|Acoustic Stimulation|Somatic Stimulation|Vestibular Stimulation
Interventions: DEVICE: multiple sensory stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: To Evaluate the Efficacy, Safety, and Tolerability of BBT-877 in Patients With IPF
Status: ACTIVE_NOT_RECRUITING
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: DRUG: BBT-877|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Dose-range Finding Study of MAA868 in Patients With Atrial Fibrillation
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: BIOLOGICAL: MAA868 Cohort 1|BIOLOGICAL: MAA868 Cohort 2|BIOLOGICAL: MAA868 Cohort 3|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Supporting Primary Care in Diagnosis and Choice of Treatment for Patients With Psychosocial Symptoms: SGEPsyScan.
Status: COMPLETED
Conditions: Mental Disorders
Interventions: OTHER: SGE-PsyScan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effect of Propolis on Patients Infected With H. Pylori
Status: UNKNOWN
Conditions: Helicobacter Pylori Infection
Interventions: DIETARY_SUPPLEMENT: propolis solved in lactic acid solvent|DRUG: Amoxicillin-Clarithromycin-Lansoprazole|OTHER: IV saline 0.9%|OTHER: Lactic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of BLYG8824A in Participants With Locally Advanced or Metastatic Colorectal Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Colorectal Cancer
Interventions: DRUG: BLYG8824A
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study of CTX-100 Inhalation Solution (Formerly ETX-100)
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: DRUG: CTX-100 (formerly ETX-100) (hyaluronic acid)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of CLE-400 (Topical Gel) for the Treatment of Chronic Pruritus in Adult Subjects With Notalgia Paresthetica
Status: RECRUITING
Conditions: Chronic Pruritus in Adult Subjects With Notalgia Paresthetica (NP)
Interventions: DRUG: CLE-400|DRUG: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prognostic Value of Heart-type Fatty Acid-Binding Protein (h-FABP) in Acute Pulmonary Embolism
Status: COMPLETED
Conditions: Pulmonary Embolism
Interventions: BIOLOGICAL: Dosage de l'h-FABP
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Breath Synchronized Abdominal Muscle Stimulation to Facilitate Ventilator Weaning: a Pilot Study
Status: TERMINATED
Conditions: Electric Stimulation|Respiration, Artificial|Ventilator Weaning
Interventions: DEVICE: Breath synchronized abdominal NMES|DEVICE: Sham breath synchronized abdominal NMES
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acute Ischemic Stroke Interventional Study
Status: COMPLETED
Conditions: Acute Ischemic Stroke
Interventions: DRUG: Intravenous ACT017 1000 mg|OTHER: Intravenous Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Transvaginal Botulinum Toxin A for Interstitial Cystitis / Bladder Pain Syndrome
Status: ACTIVE_NOT_RECRUITING
Conditions: Interstitial Cystitis|Bladder Pain Syndrome
Interventions: DRUG: Transvaginal botulinum toxin A (BTA) injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adapting the HITSystem to Support Prevention of Mother-to-child HIV Transmission
Status: COMPLETED
Conditions: HIV
Interventions: BEHAVIORAL: HIV Infant Tracking System (HITSystem) 2.0|BEHAVIORAL: Standard of PMTCT care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparison of Kinesio Taping and Local Injection in Chronic Low Back Pain
Status: COMPLETED
Conditions: Chronic Low Back Pain
Interventions: OTHER: kinesio tape|OTHER: local anesthetic|OTHER: local serum physiologic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Enhanced Programming Stimulation With the Enterra® Therapy System
Status: RECRUITING
Conditions: Gastroparesis|Gastroparesis Nondiabetic|Gastroparesis Due to Diabetes Mellitus
Interventions: DEVICE: Enterra Therapy System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Transcutaneous Tibial Nerve Stimulation of Patients With Overactive Bladder (OAB) Syndrome
Status: COMPLETED
Conditions: Overactive Bladder|Multiple Sclerosis
Interventions: DEVICE: The Geko
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: B&O for TLH Post-operative Pain and Nausea
Status: COMPLETED
Conditions: Hysterectomy|Pain, Postoperative
Interventions: DRUG: Belladonna Opium|DRUG: Glycerin Suppository
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigating the Anti-inflammatory Effects of Frondanol in Adults With Inflammatory Bowel Disease
Status: RECRUITING
Conditions: Ulcerative Colitis Chronic Mild|Ulcerative Colitis Chronic Moderate|Crohn Colitis
Interventions: DRUG: Frondanol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lymph Node 14v Dissection in Clinical Stage T3N+, T4N+ of Gastric Cancer
Status: UNKNOWN
Conditions: Gastric Cancer
Interventions: PROCEDURE: D2 lymphadenectomy|PROCEDURE: D2 and #14v lymphadenectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Duloxetine to Prevent Oxaliplatin-Induced Peripheral Neuropathy in Patients With Stage II-III Colorectal Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Stage II Colorectal Cancer AJCC v8|Stage III Colorectal Cancer AJCC v8
Interventions: DRUG: Oxaliplatin|DRUG: Duloxetine Hydrochloride|DRUG: Duloxetine|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Vitamin D3 Treatment and Homocysteine Concentrations Among Overweight Reproductive Women
Status: COMPLETED
Conditions: Homocystinaemia|Vitamin D Deficiency
Interventions: DRUG: Vit D|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate How Effective and Safe Solifenacin Succinate Suspension is in Treating Children/Adolescents Aged 5 to Less Than 18 Years With Symptoms of Overactive Bladder (OAB) Compared to a Non-active Drug
Status: COMPLETED
Conditions: Urinary Bladder, Overactive
Interventions: DRUG: Solifenacin Succinate Suspension|DRUG: Placebo|BEHAVIORAL: Urotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Mitopure (Urolithin A) on Skeletal Muscle Function, Iron Metabolism and Endurance Performance
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Mitopure|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Social Cognition in Youth Who Have a First Degree Relative With Schizophrenia
Status: RECRUITING
Conditions: Schizophrenia
Interventions: BEHAVIORAL: Emotion Recognition Training|BEHAVIORAL: Active Control Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Patients Perceptions of Using the "Libre" System Compared With Conventional SMBG in Adolescents With Type 1 Diabetes The Libre Sat Trial
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: DEVICE: Libre Flash CGMS|DEVICE: Self-Measurement Blood Glucose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Biomarkers in Samples of Bone Marrow From Patients With Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Leukemia
Interventions: GENETIC: DNA analysis|GENETIC: gene rearrangement analysis|GENETIC: microarray analysis|GENETIC: polymerase chain reaction|OTHER: immunological diagnostic method|OTHER: laboratory biomarker analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Increasing Human Papillomavirus Vaccine Uptake in Low-Income, Ethnic Minority Adolescents in Los Angeles County
Status: COMPLETED
Conditions: Human Papilloma Virus Infection
Interventions: BEHAVIORAL: Tailored education and referral|BEHAVIORAL: Staff training and patient reminders|BEHAVIORAL: Clinic-level reminder systems
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety, Tolerability, Efficacy Study of PUR 0110 Rectal Enema in Mild-to-Moderate Distal Ulcerative Colitis
Status: COMPLETED
Conditions: Left-Sided Ulcerative Colitis|Proctosigmoiditis
Interventions: DRUG: PUR 0110 Rectal Enema 250 mg|DRUG: PUR 0110 Rectal Enema 500 mg|DRUG: PUR 0110 Rectal Enema 1000 mg|DRUG: Placebo Enema
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Latanoprost/Brinzolamide BID Versus Latanoprost BID in Patients With OAG or OH
Status: WITHDRAWN
Conditions: Open Angle Glaucoma|Ocular Hypertension
Interventions: DRUG: Latanoprost+Brinzolamide combination|DRUG: Latanoprost
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of KW-2478 in Combination With Bortezomib in Subjects With Relapsed and/or Refractory Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: KW-2478|DRUG: Bortezomib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of Two Doses of aH5N1 Vaccine in Adult and Elderly Subjects With and Without Immunosuppressive Conditions *aH5N1:Monovalent H5N1 Influenza Vaccine
Status: COMPLETED
Conditions: Influenza, Human|Flu, Human|Flu, Avian|Influenza|Influenza A Virus, H5N1 Subtype
Interventions: BIOLOGICAL: Novartis Investigational H5N1 vaccine|BIOLOGICAL: Novartis Investigational H5N1 vaccine|BIOLOGICAL: Novartis Seasonal Influenza Vaccine|BIOLOGICAL: Novartis Seasonal Influenza Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Adipose Tissue After Switch to Doravirine
Status: ACTIVE_NOT_RECRUITING
Conditions: HIV Infections
Interventions: DRUG: Switch from an INSTI-based regimen to the non INSTI-based regimen combining TDF/3TC/Doravirine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Evaluation of a Topical Treatment for Actinic Keratosis
Status: COMPLETED
Conditions: Actinic Keratosis of Face and Scalp
Interventions: DRUG: AD17137 topical treatment|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Head Position After Endovascular Therapy
Status: RECRUITING
Conditions: Stroke, Acute|Endovascular Therapy
Interventions: OTHER: The lying flat (0°-10°) head position for 72 hours|OTHER: The The head elevation (30°-40°) position for 72 hours
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: The Pharmacokinetics of Dolutegravir, Darunavir/Cobocistat When Co-administered in Healthy Volunteers
Status: COMPLETED
Conditions: HIV
Interventions: DRUG: Tivicay|DRUG: Rezolsta
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Influence of Somatuline Autogel 120mg on Post-operative Drainage After Total Mesorectum Excision for Rectumcarcinoma
Status: COMPLETED
Conditions: Rectal Carcinoma
Interventions: DRUG: Lanreotide Autogel 120mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Functional MRI of Hypoxia-mediated Rectal Cancer Aggressiveness
Status: COMPLETED
Conditions: Rectal Diseases|Rectal Neoplasms|Gastrointestinal Diseases|Gastrointestinal Neoplasms
Interventions: PROCEDURE: new functional magnetic resonance imaging (MRI) protocols
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: CYclosporine A in Shockable Out-of-hospital Cardiac Arrest ResUScitation
Status: WITHDRAWN
Conditions: Shockable Out of Hospital Cardiac Arrest
Interventions: DRUG: Single intravenous bolus of cyclosporine A (2.5 mg/kg) at the onset of resuscitation|DRUG: Single intravenous bolus of placebo at the onset of resuscitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Collagen Protein Versus Placebo on Muscle Recovery
Status: NOT_YET_RECRUITING
Conditions: Anthropometrics: Height and Weight|Isometric Standing and Seated Plantarflexion|Calf Muscle Thickness|Achilles Tendon Length and Thickness|Myotonography of the Calf Musculature and Achilles Tendon|Pain Pressure Threshold of the Calf|Pain Scale|Endurance Calf Test|Dietary Analysis
Interventions: DIETARY_SUPPLEMENT: Collagen|DIETARY_SUPPLEMENT: Maltodextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: pCCLCHIM-p47 (Lentiviral Vector Transduced CD34 Plus Cells) in Patients With p47 Autosomal Recessive Chronic Granulomatous Disease (AR-CGD)
Status: ENROLLING_BY_INVITATION
Conditions: p47|Autosomal Recessive|Chronic Granulomatous Disease
Interventions: BIOLOGICAL: Cryopreserved Autologous CD34+ cells transduced with pCCLCHIM-p47
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cladribine and Rituximab as Remission Induction Therapy Followed By Rituximab and Stem Cell Mobilization in Treating Patients With CLL
Status: COMPLETED
Conditions: Leukemia
Interventions: BIOLOGICAL: filgrastim|BIOLOGICAL: rituximab|DRUG: CHOP regimen|DRUG: cladribine|DRUG: cyclophosphamide|DRUG: doxorubicin hydrochloride|DRUG: prednisone|DRUG: vincristine sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 18F-Fluorocholine for the Detection of Parathyroid Adenomas
Status: COMPLETED
Conditions: Hyperparathyroidism, Primary
Interventions: DRUG: 18F-Fluorocholine|PROCEDURE: Positron Emission Tomography (PET)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of a Self-hypnosis on Attention Disorders and Anxiety in Children With Attention Deficit/Hyperactivity Disorder
Status: RECRUITING
Conditions: Attention Deficit/Hyperactivity Disorder
Interventions: BEHAVIORAL: Self-hypnosis application|OTHER: Questionnaires
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of Budesonide and How It Interacts With Antifungal Drugs in People With Gastrointestinal Graft-Versus-Host Disease
Status: TERMINATED
Conditions: Stem Cell Transplantation|Graft vs Host Disease
Interventions: DRUG: Budesonide|DRUG: Fluconazole|DRUG: Voriconazole|DRUG: Micafungin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Enfortumab Vedotin Versus (vs) Chemotherapy in Subjects With Previously Treated Locally Advanced or Metastatic Urothelial Cancer (EV-301)
Status: ACTIVE_NOT_RECRUITING
Conditions: Ureteral Cancer|Urothelial Cancer|Bladder Cancer
Interventions: DRUG: Enfortumab Vedotin|DRUG: Docetaxel|DRUG: Vinflunine|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vaginal Microbiome Exposure and Immune Responses in C-section Infants
Status: RECRUITING
Conditions: Allergic Diseases|Asthma
Interventions: BIOLOGICAL: C-section -Vaginal seeding|DRUG: C-section - Placebo Seeding|OTHER: standard care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of FID 114675A on Lens Wettability
Status: COMPLETED
Conditions: Contact Lens Wettability
Interventions: DEVICE: FID 114675A multi-purpose disinfecting solution (MPDS)|DEVICE: Soft contact lens|DEVICE: Blister pack solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Sugammadex Versus Neostigmine in Pediatric Less Than Two Years Undergoing Cardiac Catheterization
Status: COMPLETED
Conditions: Cardiac Catheterization
Interventions: DRUG: Reversal Neostigmine|DRUG: Reversal Sugammadex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Therapeutic Confirmatory Study to Evaluate the Efficacy and Safety of Cilostazol in Subjects With Vasospastic Angina
Status: COMPLETED
Conditions: Vasospastic Angina
Interventions: DRUG: Cilostazol|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Anti-CD22 CAR-T Therapy for CD19-refractory or Resistant Lymphoma Patients
Status: UNKNOWN
Conditions: Recurrent Adult Diffuse Large Cell Lymphoma|Recurrent Follicular Lymphoma|Recurrent Mantle Cell Lymphoma|Stage III/IV Adult Diffuse Large Cell Lymphoma|Stage III/IV Follicular Lymphoma|Stage III/IV Mantle Cell Lymphoma
Interventions: DRUG: Retroviral vector-transduced autologous T cells to express CD22-specific CARs
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Controlled Trial of Long-term Treatment Effectiveness for Meibomian Gland Dysfunction (MGD) and Dry Eye
Status: COMPLETED
Conditions: Meibomian Gland Dysfunction|Dry Eye
Interventions: DEVICE: LipiFlow System|DEVICE: Warm Compress Therapy + Lid Scrub
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Outcomes of Seamless ADL Training Between Occupational Therapist and Nurse in Stroke Patients
Status: COMPLETED
Conditions: Stroke
Interventions: PROCEDURE: Seamless ADL training|PROCEDURE: Conventional ADL training
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Finding Treatments for COVID-19: A Trial of Antiviral Pharmacodynamics in Early Symptomatic COVID-19 (PLATCOV)
Status: RECRUITING
Conditions: COVID-19
Interventions: DRUG: Nirmatrelvir/ritonavir (e.g. PAXLOVID™)|DRUG: Nitazoxanide|DRUG: Molnupiravir and nirmatrelvir/ritonavir (e.g. PAXLOVID™)|DRUG: Hydroxychloroquine|OTHER: No treatment|DRUG: Monoclonal antibodies|DRUG: Fluoxetine|DRUG: Molnupiravir|DRUG: Sotrovimab|DRUG: Ensitrelvir|DRUG: Monoclonal antibodies|DRUG: Favipiravir|DRUG: Ivermectin|DRUG: Remdesivir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Complementary Testing to Evaluate Immunogenicity of Human Papillomavirus (HPV) Vaccine (580299) in Healthy Female Subjects Aged >/= 26 Years
Status: COMPLETED
Conditions: Infections, Papillomavirus
Interventions: BIOLOGICAL: Placebo|BIOLOGICAL: Cervarix TM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Prospective Placebo-controlled Study of Synochi Scar Spray
Status: NOT_YET_RECRUITING
Conditions: Burns Multiple
Interventions: OTHER: Synochi Scar Spray Cosmetic|OTHER: Synochi Scar Spray Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Impact of JuicePlus+ on the Health Status of an Overweight Stressed Population
Status: COMPLETED
Conditions: Inflammation
Interventions: DIETARY_SUPPLEMENT: Juice Plus+|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Natalizumab on Infarct Volume in Acute Ischemic Stroke
Status: COMPLETED
Conditions: Acute Ischemic Stroke
Interventions: DRUG: natalizumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Biomarkers in Neural Disorders
Status: COMPLETED
Conditions: Parkinson's Disease|Alzheimer's Disease|Progressive Supranuclear Palsy|Essential Tremor|Multiple System Atrophy|Drug Induced Parkinson's Disease|Diffuse Lewy Body Disease|Myasthenia Gravis|Spinal Cord Injuries
Interventions: OTHER: Electrical Brainstem Responses|OTHER: Olfactory Tests|OTHER: Visual Deprivation|OTHER: Peripheral Nerve Stimulation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: An Efficacy and Safety Study of Long Acting Injectable Risperidone and Oral Risperidone in Participants With Schizophrenia or Schizoaffective Disorder
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Risperidone long acting injectables|DRUG: Risperidone tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Psychosocial Intervention for Young Children With Chronic Tics
Status: COMPLETED
Conditions: Tourette's Syndrome|Tourette's Disorder|Tourette's Disease|Tourette Disorder|Tourette Disease|Tic Disorder, Combined Vocal and Multiple Motor|Multiple Motor and Vocal Tic Disorder, Combined|Gilles de La Tourette's Disease|Gilles de la Tourette Syndrome|Gilles De La Tourette's Syndrome|Combined Vocal and Multiple Motor Tic Disorder|Combined Multiple Motor and Vocal Tic Disorder|Chronic Motor and Vocal Tic Disorder
Interventions: BEHAVIORAL: Comprehensive Behavioral Intervention for Tics (CBIT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Magnitude, Types, and Associated Factors of External Abdominal Hernias Among Adult Patients Visiting the Surgical Outpatient Department at Hiwotfana Comprehensive Specialized Hospital and Jugol Regional Hospital, Eastern Ethiopia: A Cross-Sectional Study
Status: COMPLETED
Conditions: Abdominal Wall Hernia
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Pre-operative Pelvic Floor Muscle Exercise on Surgical Outcomes in Women With Stress Urinary Incontinence
Status: COMPLETED
Conditions: Stress Urinary Incontinence
Interventions: OTHER: Pelvic Floor muscle strengthening exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dose Escalation Trial of Nitroglycerin, 5-flourouracil and Rad Therapy for Rectal Cancer
Status: COMPLETED
Conditions: Rectal Cancer
Interventions: DRUG: Nitroglycerin 0.2 MG/HR|DRUG: Nitroglycerin 0.4 MG/HR|DRUG: Nitroglycerin 0.6 MG/HR
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Simunye: A Couples-focused Intervention for HIV Prevention and Care in South Africa
Status: ACTIVE_NOT_RECRUITING
Conditions: Human Immunodeficiency Virus
Interventions: BEHAVIORAL: A couples-focused intervention for HIV prevention and care in South Africa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Safety And Immunogenicity Of HDT-301 Targeting A SARS-CoV-2 Variant Spike Protein
Status: ACTIVE_NOT_RECRUITING
Conditions: SARS-CoV2 Infection
Interventions: BIOLOGICAL: HDT-301
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Levofloxacin as an Empirical Therapy in Patients With Complicated Urinary Tract Infections
Status: UNKNOWN
Conditions: Urinary Tract Infection
Interventions: DRUG: Levofloxacin|DRUG: Levofloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Sensory and Motor Transcutaneous Electrical Nervous Stimulation on Electromyographic and Kinesiographic Activity of Patients With Temporomandibular Disorder: a Controlled Clinical Trial
Status: COMPLETED
Conditions: Temporomandibular Disorders
Interventions: DEVICE: Transcutaneous electrical nerve stimulation|DEVICE: Placebo transcutaneous electrical nerve stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Virtual Reality on Pain, Anxiety and Satisfaction Level Before Mammography
Status: RECRUITING
Conditions: Mammography|Early Diagnosis of Cancer
Interventions: OTHER: Virtual reality|OTHER: routine maintenance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety Study of Preimplantation Factor (PIF-1) to Treat Acute Steroid-Resistant Graft-Versus-Host Disease (GVHD)
Status: UNKNOWN
Conditions: Graft Vs Host Disease
Interventions: DRUG: Preimplantation factor (PIF-1)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Evaluation of Mechanical Assistance for the Treatment of Congestive Heart Failure (REMATCH)
Status: COMPLETED
Conditions: Cardiovascular Diseases|Heart Diseases|Heart Failure|Heart Failure, Congestive
Interventions: DEVICE: Left ventricular assist device|DEVICE: Optimal medical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Anti-Inflammatory Effect of Extrafine HFA-Beclometasone Versus HFA-Fluticasone, by Means of Inflammometry
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: extrafine HFA-beclomethasone|DRUG: HFA-fluticasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of 14-days of HMB-free Acid on Changes in Muscle During 4-days of Survival Training
Status: COMPLETED
Conditions: Survival Training
Interventions: DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: HMB-FA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: PET/CT-Assessment of Liver Tumor Ablation
Status: COMPLETED
Conditions: Liver Tumor|Liver Neoplasms
Interventions: DIAGNOSTIC_TEST: N-13 ammonia or F-18 fluorodeoxyglucose|DIAGNOSTIC_TEST: PET scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: ImproviNg rEnal Outcomes Following Coronary angiograPhy and/or percuTaneoUs coroNary intErventions
Status: RECRUITING
Conditions: Contrast-Induced Acute Kidney Injury
Interventions: PROCEDURE: Personalized hydration strategy|PROCEDURE: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of Epicardial VT Ablation Using Contact Force Irrigated Tip Catheter - Pilot Study
Status: COMPLETED
Conditions: Tachycardia, Ventricular
Interventions: PROCEDURE: Epicardial VT ablation|PROCEDURE: Endocardial VT Ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Anesthetic Efficacy of 3% Mepivacaine Plus 2% Lidocaine With 1:100,000 Epinephrine for Lower Jaw Dental Injections
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: mepivacaine + lidocaine followed by lidocaine +lidocaine|DRUG: lidocaine + lidocaine followed by mepivacaine + lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Hypercapnia on Physiological Parameters During Short-term Breathing
Status: UNKNOWN
Conditions: Hypoxia|Hypercapnia|Cardiac Output, High
Interventions: OTHER: Hypoxic|OTHER: Hypercapnic|OTHER: Hypoxic and Hypercapnic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Interrater Reliability of Infant Motor Profile
Status: UNKNOWN
Conditions: Premature Infants|Cerebral Palsy|Down Syndrome|Metabolic Disorders|Spina Bifida|Low; Birthweight, Extremely (999 Grams or Less)
Interventions: OTHER: Video based assessment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: FINDER® Instrument and FINDER® FLU A/B, RSV, SARS-CoV-2 Test Clinical Evaluation Protocol
Status: NOT_YET_RECRUITING
Conditions: Influenza A|Influenza Type B|SARS CoV 2 Infection|RSV Infection
Interventions: DIAGNOSTIC_TEST: Diagnostic Test for identification of influenzas A, influenzas B, RSV and SARS-CoV-2 infections
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Thymic Function in Patients With COVID-19
Status: COMPLETED
Conditions: Covid19
Interventions: GENETIC: Single-Nucleotide Polymorphisms (SNP) within the TCRA/D region|BIOLOGICAL: Blood sample|DIAGNOSTIC_TEST: CT Scan|BIOLOGICAL: Bronchial fibroscopy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: ABI-007 With Carboplatin as First-Line Therapy in Patients With Epithelial Ovarian, Primary Peritoneal, or Fallopian Tube Carcinoma
Status: TERMINATED
Conditions: Fallopian Tube Neoplasms|Peritoneal Neoplasms|Ovarian Neoplasms
Interventions: DRUG: ABI-007|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Real-world Evidence Study of BNT162b2 mRNA Covid-19 Vaccine Among Children in Brazil
Status: COMPLETED
Conditions: COVID-19
Interventions: BIOLOGICAL: Pfizer/BioNTech BNT162b2 mRNA COVID-19 vaccine|BIOLOGICAL: CoronaVac COVID-19 vaccine
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Nutritional Preconditioning on the Patient's Outcomes After Surgery
Status: UNKNOWN
Conditions: Major Abdominal/GI Surgery
Interventions: DIETARY_SUPPLEMENT: HMB|DIETARY_SUPPLEMENT: Protein and HMB|DIETARY_SUPPLEMENT: ERAS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Potential Benefits of Expanded Hemodialysis in Prevention of Sarcopenia
Status: COMPLETED
Conditions: Chronic Kidney Disease Requiring Chronic Dialysis
Interventions: DEVICE: A medium cut-off dialyzer (Theranova) will be used for HDx.|DEVICE: A synthetic high-flux dialyzer (Polyflux)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study to Compare ISOVUE®-250 and VISIPAQUE™ 270 for Motion Artifact and Pain in Peripheral DSA
Status: COMPLETED
Conditions: Peripheral Arterial Occlusive Disease
Interventions: DRUG: VISIPAQUE 270|DRUG: Isovue 250
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Building Emotion Awareness and Mental Health (BEAM): Community Partnership With Family Dynamics
Status: COMPLETED
Conditions: Depression, Anxiety
Interventions: BEHAVIORAL: Experimental: Building Emotion Awareness and Mental Health (BEAM)|BEHAVIORAL: Control: MoodMission
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Examining the Effect of Occupational Therapy-Based Parent Coaching on Feeding Problems in Children With a Preterm Birth
Status: NOT_YET_RECRUITING
Conditions: Feeding Behavior|Mother-Child Relations|Feeding and Eating Disorders
Interventions: BEHAVIORAL: Ergotherapy Based Parent Coaching|OTHER: Informative Brochure Distribution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Dendritic Cell Cancer Vaccine for High-grade Glioma
Status: COMPLETED
Conditions: Glioblastoma Multiforme
Interventions: DRUG: Trivax, Temozolomide, Surgery, Radiotherapy|DRUG: Temozolomide, Surgery, Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study of Oxaliplatin in Association With 5FU and Folinic Acid in the Treatment of Subjects With Non-Surgical or Advanced Metastatic Gastric Cancer
Status: COMPLETED
Conditions: Stomach Neoplasms
Interventions: DRUG: Oxaliplatin, 5-Fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Pharmacokinetics, Safety and Tolerability of HCP1903
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: HGP1910|DRUG: HGP1909|DRUG: HCP1903
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Externalization and Stimulation
Status: RECRUITING
Conditions: Healthy Participants
Interventions: PROCEDURE: High-definition transcranial direct current (HD-tDCS), active condition|PROCEDURE: High-definition transcranial direct current (HD-tDCS), placebo condition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: An Emergency Department (ED) Provider Centered Intervention for Non-Traumatic Dental Condition Management (NTDC)
Status: NOT_YET_RECRUITING
Conditions: Emergency Department Visit|Odontalgia
Interventions: BEHAVIORAL: Clinical decision support tool
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Single Dose Study to Measure Blood Levels and Safety of a Drug for Children With Overactive Bladder
Status: COMPLETED
Conditions: Overactive Bladder|Neurogenic Detrusor Overactivity
Interventions: DRUG: Solifenacin succinate suspension 5 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Relationship Between Hand Dynamometer Measurements, PFT, and mFI With Postoperative Outcomes
Status: NOT_YET_RECRUITING
Conditions: Complication,Postoperative|Lung Cancer
Interventions: DEVICE: Hand Dynamometer|DIAGNOSTIC_TEST: Pulmonary Function Test|OTHER: Modified Frailty Index
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: BAFF-var as a Biomarker of Response to B-depletive Treatment in Systemic Lupus Erythematosus and Rheumatoid Arthritis
Status: RECRUITING
Conditions: Systemic Lupus Erythematosus|Rheumatoid Arthritis|BLyS Polymorphism
Interventions: DRUG: Belimumab in SLE patients / Rituximab in RA patients
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Sarcopenia and Multimodal Rehabilitation on the Prognosis of Rectal Cancer Patients Receiving CCRT
Status: NOT_YET_RECRUITING
Conditions: Rectal Cancer
Interventions: OTHER: for excise, nutrition consultant, nutrition supplement and psychologic intervention.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Mild Alzheimer''s Disease to Assess the of Extended Release Formulation of Rosiglitazone (RSG XR)
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: Rosiglitazone (Extended Release)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Small Extracellular Vesicles and Insulin Action
Status: RECRUITING
Conditions: Obesity|Insulin Resistance|Metabolically Healthy Obesity|Obesity, Metabolically Benign
Interventions: BEHAVIORAL: People with Metabolically Unhealthy Obesity - Low Calorie Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Validation of the VascuQoL-6 Questionnaire to Assess ePROM After Revascularization for Lower Limb Peripheral Arterial Disease in German-speaking Part of Switzerland
Status: UNKNOWN
Conditions: Peripheral Arterial Disease
Interventions: OTHER: Quality of life assessment - elective|OTHER: Quality of life assessment - emergent
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Trial of an Intratumoral Injections of INXN-3001 in Subjects With Stage III or IV Melanoma
Status: COMPLETED
Conditions: Melanoma
Interventions: DRUG: INXN-1001|BIOLOGICAL: INXN-3001
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Debio 025 in Combination With PegIFN Alpha-2a and Ribavirin in Chronic HCV Patients Non-responders to Standard Treatment
Status: COMPLETED
Conditions: Chronic Hepatitis C
Interventions: DRUG: Debio 025|DRUG: Peg-IFNα2a|DRUG: Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial to Compare Antibacterial vs. Placebo Mouthwash to Reduce the Incidence of Sexually Transmitted Infections (STIs) in Men Who Have Sex With Men (MSM) Taking HIV Pre-Exposure Prophylaxis (PrEP)
Status: TERMINATED
Conditions: Sexually Transmitted Diseases
Interventions: OTHER: Mouthwash with LCM|OTHER: Mouthwash with placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Laser Acupuncture Alone or Combined With Pranayama Exercise on Inflammation in Allergic Rhinitis in Geriatrics
Status: RECRUITING
Conditions: Allergic Rhinitis
Interventions: OTHER: pranayama plus acupoint stimulation by laser|OTHER: acupoint stimulation by laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effect of an Acidic Formulation of Acalabrutinib (ACP-196), Acidic Beverage, or Grapefruit Juice on the Pharmacokinetics (PK) of ACP-196 Alone and Coadministered With Omeprazole
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: ACP-196|DRUG: Omeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pembrolizumab After Radiation Therapy and Chemotherapy in Limited Stage Small Cell Lung Cancer
Status: RECRUITING
Conditions: Limited Stage Lung Small Cell Carcinoma|Stage I Lung Cancer|Stage II Lung Cancer|Stage III Lung Cancer
Interventions: DRUG: Cisplatin|DRUG: Carboplatin|DRUG: Etoposide|BIOLOGICAL: Pembrolizumab|PROCEDURE: Computed Tomography|PROCEDURE: Positron Emission Tomography|PROCEDURE: Magnetic Resonance Imaging|PROCEDURE: Biospecimen Collection|RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of N-SWEAT Patch for Treatment of Primary Axillary Hyperhidrosis or Excessive Axillary Sweating
Status: COMPLETED
Conditions: Primary Axillary Hyperhidrosis
Interventions: DEVICE: Roll-In Cohort: Single Application of N-SWEAT Patch|DEVICE: Randomized Cohort: Single Application of N-SWEAT Patch|DEVICE: Randomized Cohort: Single Application of Sham Patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Peak Study - A Study of Pegasys (Peginterferon Alfa-2a (40KD)) in Combination With Copegus (Ribavirin) in Interferon-Naive Patients With Chronic Hepatitis C (CHC).
Status: COMPLETED
Conditions: Hepatitis C, Chronic
Interventions: DRUG: Ribavirin|DRUG: Peginterferon alfa-2b (PEG-Intron)|DRUG: Ribavirin|DRUG: Peginterferon alfa-2a [Pegasys]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioavailability Study of Fixed Dose Combination (FDC) Formulations of Dapagliflozin and Metformin XR Versus Individual Component Coadministered to Healthy Subjects in a Fasted State
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus (T2DM)
Interventions: DRUG: Dapagliflozin|DRUG: Metformin XR|DRUG: Glucophage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: AMO-01 to Treat Adolescents and Adults With Phelan-McDermid Syndrome (PMS) and Co-morbid Epilepsy
Status: COMPLETED
Conditions: Phelan-McDermid Syndrome|Epilepsy
Interventions: DRUG: AMO-01
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT