pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Antiplatelet Therapy in Chronic Urticaria
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Urticaria
Interventions: DRUG: Desloratadine plus cilostazol and dipyridamole|DRUG: Desloratadine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Hyaluronic Acid in the Regeneration of Infrabony Defects
Status: COMPLETED
Conditions: Intrabony Periodontal Defect
Interventions: DEVICE: enamel matrix derivative (EMD)|DEVICE: hyaluronic acid (HA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Obesity, Lifestyle and Work Intervention
Status: COMPLETED
Conditions: Obesity|Morbid Obesity|Sick-leave|Work Related Illnesses|Life Style
Interventions: BEHAVIORAL: Lifestyle and work intervention|BEHAVIORAL: Lifestyle intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Theta-burst Repetitive Transcranial Magnetic Stimulation (TBS) of the Right Inferior Frontal Gyrus for Treatment of Nicotine Dependence
Status: NOT_YET_RECRUITING
Conditions: Tobacco Use Disorder
Interventions: DEVICE: Continuous Theta-burst stimulation (cTBS)|DEVICE: Sham Continuous Theta-burst stimulation (cTBS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Visually Enhanced Education About Prostate Cancer
Status: COMPLETED
Conditions: Stage I Prostate Cancer|Stage II Prostate Cancer|Stage III Prostate Cancer
Interventions: OTHER: Visually enhanced prostate cancer educational presentation|OTHER: Standard prostate cancer education presentation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of M802 (HER2 and CD3) in HER2-Positive Advanced Solid Tumors
Status: UNKNOWN
Conditions: HER2-Positive Solid Tumors
Interventions: DRUG: Chort 1 of M802|DRUG: Chort 2 of M802|DRUG: Cohort 3 of M802|DRUG: Cohort 4 of M802|DRUG: Cohort 5 of M802|DRUG: Cohort 6 of M802|DRUG: Cohort 7 of M802|DRUG: Cohort 8 of M802
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Irritation Potential of ATx201 in Healthy Volunteers
Status: COMPLETED
Conditions: Irritation Potential of Topic Agent
Interventions: DRUG: ATx201 Gel 2%|DRUG: ATx201 Gel 4%|DRUG: Positive Control|DRUG: Negative Control|DRUG: ATx201 Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Pea Protein and Postprandial Response (PEA)
Status: COMPLETED
Conditions: Metabolic Syndrome
Interventions: OTHER: High-fat shake with Pea protein|OTHER: High-fat shake with Pea protein hydrolysate|OTHER: High-fat shake - Control|OTHER: High-fat shake with Gluten protein|OTHER: High-fat shake with Gluten protein hydrolysate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of Functional and Aesthetic Outcomes After Wassel IV Thumb Duplication Surgery in Pediatric Population, With a Follow-up of at Least One Year
Status: NOT_YET_RECRUITING
Conditions: Wassel IV Thumb Duplication
Interventions: PROCEDURE: Wassel IV Thumb Duplication Surgery
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study to Evaluate Efficacy and Safety of Two Drug Regimens in Subjects With Moderate to Severe Crohn's Disease
Status: COMPLETED
Conditions: Crohn's Disease
Interventions: DRUG: Adalimumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multiple Ascending Dose Study of GLPG0492 in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: GLPG0492|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Evaluation of Wet Age-Related Macular Degeneration (AMD) Genetic Profile Interactions With Ranibizumab Treatment Outcomes
Status: COMPLETED
Conditions: Age Related Macular Degeneration
Interventions: DRUG: Ranibizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing the Safety, Tolerability, and Pharmacokinetics of Sabirnetug IV and Sabirnetug + rHuPH20 SC in Healthy Participants
Status: RECRUITING
Conditions: Alzheimer Disease
Interventions: DRUG: sabirnetug (ACU193)|COMBINATION_PRODUCT: Sabirnetug + rHuPH20
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate and Compare the Efficacy and Safety of AZM and AML Combined and Alone in Mild-to-moderate Essential Hypertensive Subjects
Status: ACTIVE_NOT_RECRUITING
Conditions: Essential Hypertension
Interventions: DRUG: AZM X mg + AML Y mg|DRUG: AZM X mg + AML Y' mg|DRUG: AZM X' mg + AML Y mg|DRUG: AZM X' mg + AML Y' mg|DRUG: AZM X mg|DRUG: AZM X' mg|DRUG: AML Y mg|DRUG: AML Y' mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Femoral Nerve Block With Bupivacaine and Adjuvant Dexamethasone in Patients With Hip Fracture
Status: TERMINATED
Conditions: Hip Fracture
Interventions: DRUG: Dexamethasone|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cardiovascular Effects of High-Intensity Interval Training (HIIT)
Status: COMPLETED
Conditions: Healthy Sedentary Adults With BP <140/90
Interventions: BEHAVIORAL: High-Intensity Interval Training|BEHAVIORAL: Moderate-Intensity Continuous Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Arginine and Citrulline Supplementation on Endothelial Dysfunction in Mitochondrial Diseases
Status: COMPLETED
Conditions: Mitochondrial Diseases
Interventions: DIETARY_SUPPLEMENT: Arginine|DIETARY_SUPPLEMENT: Citrulline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Systemic Versus Local Dexmedetomidine as An Adjuvant to Bupivacaine in Ultrasound Guided Erector Spinae Block
Status: RECRUITING
Conditions: Erector Spinae Block|Dexmedetomidine
Interventions: DRUG: Dexmedetomidine Injection [Precedex]|DRUG: Bupivacaine Hydrochloride|DRUG: Dexmedetomidine in 0.9 % NaCl 200 Mcg/50 mL (4 Mcg/mL) INTRAVEN INFUSION BOTTLE (ML)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase IIb Study to Evaluate Efficacy and Tolerability of ODX (Osteodex) in Metastatic CRPC
Status: TERMINATED
Conditions: Prostate Cancer Metastatic
Interventions: DRUG: Osteodex|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Proactive Treatment of Tacrolimus Ointment for Adult Facial Seborrheic Dermatitis
Status: COMPLETED
Conditions: Seborrheic Dermatitis
Interventions: DRUG: Tacrolimus|DRUG: Tacrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Targeting Auditory Hallucinations With Alternating Current Stimulation
Status: COMPLETED
Conditions: Schizophrenia|Schizo Affective Disorder
Interventions: DEVICE: tACS treatment week|DEVICE: tACS sham week|DEVICE: Maintenance tACS|DEVICE: Maintenance Sham tACS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Advanced Radiotherapy (ART) in Gynecological Cancer Patients (GYN-ART)
Status: RECRUITING
Conditions: Gynecologic Cancer|Radiotherapy Side Effect|Radiotherapy; Complications|Survivorship|Progression, Disease|Progression, Clinical
Interventions: RADIATION: Image Guided Radiotherapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phase 2b Study in NASH to Assess IVA337
Status: COMPLETED
Conditions: Non-Alcoholic Steatohepatitis (NASH)
Interventions: DRUG: IVA337|DRUG: IVA337|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pentoxifylline in Lupus Nephritis
Status: WITHDRAWN
Conditions: Lupus Nephritis
Interventions: DRUG: Pentoxifylline|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Autologous Stem Cell Transplantation of Cells Engineered to Express Alpha-Galactosidase A in Patients With Fabry Disease
Status: COMPLETED
Conditions: Fabry Disease
Interventions: BIOLOGICAL: Lentivirus Alpha-gal A transduced stem cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Metabolic Disorders and Vertigo
Status: UNKNOWN
Conditions: Benign Paroxysmal Positional Vertigo (BPPV)|Vestibular Migraine|Central Positional Vertigo|Vestibular Neuritis|Meniere Disease
Interventions: DIAGNOSTIC_TEST: diagnostic blood test|DIAGNOSTIC_TEST: neuropsychological test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Two Therapies for Upper Esophageal Sphincter (UES) Dysphagia
Status: COMPLETED
Conditions: Deglutition Disorders
Interventions: PROCEDURE: Shaker Exercise vs. Traditional Dysphagia Therapy Regime
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: High-Dose Steroid for Knee Arthroplasty
Status: COMPLETED
Conditions: Postoperative Pain|Postoperative Nausea and Vomiting|Knee Osteoarthritis|Perioperative/Postoperative Complications|Surgery
Interventions: DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial of Silk Peptide for the Evaluation of Efficacy on Immune Function
Status: UNKNOWN
Conditions: Normal Healthy Subjects
Interventions: DIETARY_SUPPLEMENT: Investigational Product (Silk Peptide)|DIETARY_SUPPLEMENT: Control Group - Placebo Product
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Orelabrutinib in Combination With Thiotepa in Refractory and Relapsed Primary CNS Lymphoma
Status: UNKNOWN
Conditions: Refractory and Relapsed Primary CNS Lymphoma|PCNSL|Non Hodgkin Lymphoma
Interventions: DRUG: Orelabrutinib|DRUG: Orelabrutinib|DRUG: Thiotepa
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Analgesic Efficacy and Safety of V120083 in Subjects With Osteoarthritis (OA) of the Knee
Status: COMPLETED
Conditions: Osteo Arthritis Knee
Interventions: DRUG: V120083|DRUG: Naproxen|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Psychological Intervention for Family Caregivers of Palliative Care Patients
Status: COMPLETED
Conditions: Palliative Care
Interventions: OTHER: Psychological intervention for family caregivers of patients at the end of life
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Research on Risk Factors and Interventions of Polycystic Ovary Syndrome Complicated With Depression and Anxiety
Status: RECRUITING
Conditions: PCOS (Polycystic Ovary Syndrome) of Bilateral Ovaries|Depression, Anxiety
Interventions: DRUG: Oral Contraceptives, Combined|DRUG: Metformin Pill|OTHER: lifestyle intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Ulimorelin Study of Efficacy and Safety (ULISES 007)
Status: COMPLETED
Conditions: Gastrointestinal Dysmotility
Interventions: DRUG: Ulimorelin Intravenously (IV)|DRUG: Ulimorelin Intravenously (IV)|DRUG: 5% dextrose in water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare Two Techniques for the Reconstruction of the Anterior Cruciate Ligament
Status: RECRUITING
Conditions: Complete Tear, Knee, Anterior Cruciate Ligament
Interventions: PROCEDURE: ACL reconstruction preserving insertion|PROCEDURE: ACL reconstruction detaching insertion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy Before Surgery in Treating Patients With High Grade Upper Urinary Tract Cancer
Status: COMPLETED
Conditions: High Grade Upper Tract Urothelial Carcinoma
Interventions: DRUG: Methotrexate|DRUG: Vinblastine|DRUG: Doxorubicin|DRUG: Cisplatin|DRUG: Gemcitabine|DRUG: Carboplatin|DRUG: Pegfilgrastim|PROCEDURE: Nephroureterectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Explore the Benefits of the MonaLisa Touch® System in Gynaecological Cancer Patients Treated by (Chemo)-RT
Status: RECRUITING
Conditions: Gynecologic Cancer
Interventions: DEVICE: MonaLisa Touch device|DEVICE: Vaginal dilatators
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of BI 201335 (Faldaprevir) in Combination With Pegylated Interferon-alpha and Ribavirin in Treatment-naïve Genotype 1 Hepatitis C Infected Patients (STARTverso 2)
Status: COMPLETED
Conditions: Hepatitis C
Interventions: DRUG: BI201335|DRUG: PegIFN/RBV|DRUG: BI201335|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Different Lugol's Solution Concentration for Image Quality of Esophageal Lesions in Chromoendoscopy With Iodine Staining
Status: UNKNOWN
Conditions: Image Quality of Early Esophageal Squamous Neoplasia|Endoscopists'Subjective Assessments
Interventions: DRUG: 1.2% Lugol's solution|DRUG: 1.0% Lugol's solution|DRUG: 0.8% Lugol's solution|DRUG: 0.6% Lugol's solution|DRUG: 0.4% Lugol's solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Arabin Pessary Combine With Vaginal Progesterone Compare With Vaginal Progesterone Alone to Prevent Preterm Delivery in Singleton Pregnancies
Status: TERMINATED
Conditions: Focus: Prevent Preterm Delivery|Incidental Short Cervix at Mid-trimester
Interventions: DRUG: Arabin Pessary
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect on Sleep of Surgical Treatment of Severe Nasal Obstruction
Status: COMPLETED
Conditions: Sleep Apnea|Obstructive Sleep Apnea|Nasal Obstruction
Interventions: OTHER: actigraphy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Neoadjuvant Radiotherapy and Immediate Implant-Based Breast Reconstruction
Status: RECRUITING
Conditions: Breast Cancer|Implant Breast Reconstruction|Neoadjuvant Radiotherapy
Interventions: RADIATION: Neoadjuvant radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Communication Modalities for Promoting Flu Shots
Status: COMPLETED
Conditions: Influenza Vaccination|Health Promotion|Health Behavior|Risk Reduction
Interventions: BEHAVIORAL: Letter|BEHAVIORAL: Patient portal|BEHAVIORAL: SMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Investigation of the Ability of the TENA SmartCare Change Indicator to Reduce the Number of Manual Checks Between Changes of Absorbing Incontinence Products
Status: COMPLETED
Conditions: Urinary Incontinence
Interventions: DEVICE: TENA SmartCare Change Indicator
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Bioavailability Study of Rifabutin and Lopinavir/Ritonavir in Healthy Adult Subjects
Status: TERMINATED
Conditions: HIV|Tuberculosis
Interventions: DRUG: lopinavir/ritonavir|DRUG: rifabutin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High-intensity Rosuvastatin and Moderate-intensity Rosuvastatin/Ezetimibe in ASCVD Patients
Status: COMPLETED
Conditions: ASCVD
Interventions: DRUG: Rosuvamibe|DRUG: Monorova
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized Controlled Trial on Malaria Primaquine Treatment in Timika, Indonesia (TRIPI)
Status: COMPLETED
Conditions: Uncomplicated Malaria
Interventions: DRUG: PQ supervised|DRUG: PQ unsupervised
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Caregiver Stress: Interventions to Promote Health and Wellbeing
Status: COMPLETED
Conditions: Health Promotion
Interventions: BEHAVIORAL: Usual Care|BEHAVIORAL: Psycho-education|BEHAVIORAL: Psycho-education plus physical exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of TQ-B3525 in Subjects With Relapse/Refractory Diffuse Large B-cell Lymphoma （DLBCL）
Status: UNKNOWN
Conditions: Diffuse Large B-cell Lymphoma
Interventions: DRUG: TQ-B3525 tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Screening of Endovascular Thrombectomy With MRI in Acute Ischemic Stroke
Status: COMPLETED
Conditions: Fluid-attenuated Inversion Recovery Sequence Vascular Hyperintensity-diffusion-weighted Imaging Mismatch(FVH-DWI Mismatch)|Image Evaluation|Endovascular Thrombectomy
Interventions: DIAGNOSTIC_TEST: Surgical criteria
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Randomized,Open,Controlled Clinical Study to Evaluate the Efficacy of ASC09F and Ritonavir for 2019-nCoV Pneumonia
Status: UNKNOWN
Conditions: 2019-nCoV Pneumonia
Interventions: DRUG: ASC09F+Oseltamivir|DRUG: Ritonavir+Oseltamivir|DRUG: Oseltamivir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Calcium and Vitamin D Malnutrition in Elderly Women
Status: COMPLETED
Conditions: Osteoporosis|Secondary Hyperparathyroidism
Interventions: DIETARY_SUPPLEMENT: calcium supplementation|DIETARY_SUPPLEMENT: calcium and vitamin D3 supplementation|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Oral Supplementation With Active Collagen Peptides and Skin Health Improvement
Status: COMPLETED
Conditions: Facial Wrinkles|Skin Hydration
Interventions: DIETARY_SUPPLEMENT: Bioactive collagen peptides|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Testing Nivolumab and Ipilimumab With Short-Course Radiation in Locally Advanced Rectal Cancer
Status: SUSPENDED
Conditions: Locally Advanced Rectal Adenocarcinoma|Stage II Rectal Cancer AJCC v8|Stage III Rectal Cancer AJCC v8
Interventions: PROCEDURE: Computed Tomography|BIOLOGICAL: Ipilimumab|PROCEDURE: Magnetic Resonance Imaging|BIOLOGICAL: Nivolumab|RADIATION: Radiation Therapy|PROCEDURE: Sigmoidoscopy|PROCEDURE: Total Mesorectal Excision
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Aliskiren and Amlodipine on Insulin Resistance and Endothelial Dysfunction in Patients With Hypertension and Metabolic Syndrome
Status: COMPLETED
Conditions: High Blood Pressure|Metabolic Syndrome|Insulin Resistance|Endothelial Dysfunction
Interventions: DRUG: Aliskiren|DRUG: Amlodipine|DRUG: Placebo Aliskiren|DRUG: Placebo Amlodipine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Targeting CD19/CD20 Dual-targeted Cell in Patients With Relapsed/Refractory B-cell Non-Hodgkin Lymphoma
Status: RECRUITING
Conditions: B-Cell Non-Hodgkin Lymphoma-Recurrent|B-Cell Non-Hodgkin Lymphoma-Refractory
Interventions: BIOLOGICAL: LUCAR-G39D cells product
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Triapine, Cisplatin, and Radiation Therapy in Treating Patients With Cervical Cancer or Vaginal Cancer
Status: COMPLETED
Conditions: Recurrent Cervical Cancer|Recurrent Vaginal Cancer|Stage IB Cervical Cancer|Stage II Vaginal Cancer|Stage IIA Cervical Cancer|Stage IIB Cervical Cancer|Stage III Cervical Cancer|Stage III Vaginal Cancer|Stage IVA Cervical Cancer|Stage IVA Vaginal Cancer|Stage IVB Cervical Cancer|Stage IVB Vaginal Cancer|Therapy-related Toxicity
Interventions: DRUG: triapine|DRUG: cisplatin|RADIATION: external beam radiation therapy|PROCEDURE: quality-of-life assessment|OTHER: questionnaire administration|RADIATION: fludeoxyglucose F 18|PROCEDURE: positron emission tomography|PROCEDURE: computed tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Patient-centered Community Health Worker Support to Help Patients Control Chronic Disease
Status: COMPLETED
Conditions: Obesity|Diabetes|Hypertension|Asthma/COPD With Tobacco Dependence
Interventions: BEHAVIORAL: CHW Goal Support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Early Feasibility Study for the Foldax TRIA Mitral Heart Valve Replacement
Status: ACTIVE_NOT_RECRUITING
Conditions: Mitral Valve Disease|Mitral Valve Stenosis|Mitral Valve Failure
Interventions: DEVICE: Foldax TRIA Mitral Valve
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I Open-Label Dose Escalation Study of Intravenous INKmune In Patients With MDS or AML
Status: TERMINATED
Conditions: Cancer|MDS-EB|Myelodysplastic Syndromes|Acute Myeloid Leukemia|AML
Interventions: BIOLOGICAL: INKmune
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Celecoxib in Patients With Newly Diagnosed GBM Who Are Receiving Anticonvulsant Drugs and Undergoing RT
Status: TERMINATED
Conditions: Brain and Central Nervous System Tumors
Interventions: RADIATION: radiation therapy|DRUG: Celecoxib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 3D-printed Reconstruction Automated Matching System Predicts Size of Double-lumen Tube: a Prospective Double-blinded Randomized Controlled Trial
Status: NOT_YET_RECRUITING
Conditions: Lung Cancer|Lung Diseases|Tracheal Intubation Morbidity|Throat Injury|Bronchus; Injury
Interventions: OTHER: 3D reconstruction automatic matching system|OTHER: traditional method for selecting double lumen tube
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy and Radiation Following Pancreatic Surgery
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: PROCEDURE: Pancreatic Surgery|RADIATION: Radiation therapy|DRUG: Cisplatin|DRUG: 5-FU|DRUG: Alpha-interferon|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I Clinical Trial Using Genetically Engineered Autologous T Cells to Express Chimeric Antigen Receptor (CAR) for Treatment of Patients With Refractory or Relapsed CD19-positive B Lymphoid Malignancies
Status: NOT_YET_RECRUITING
Conditions: Acute Lymphoblastic Leukemia, in Relapse|Acute Lymphoblastic Leukemia Refractory|B-cell Lymphoma Recurrent|B-cell Lymphoma Refractory|Chronic Lymphocytic Leukemia Recurrent|Chronic Lymphocytic Leukemia Refractory
Interventions: DRUG: Cyclophosphamide|DRUG: Fludarabine|BIOLOGICAL: Chimeric antigen receptor T cells to be implemented in a "3 + 3" design on day 0
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the ZN-d5 and ZN-c3 in Subjects With Acute Myeloid Leukemia (AML)
Status: RECRUITING
Conditions: Acute Myeloid Leukemia (AML)
Interventions: DRUG: ZN-d5 ZN-c3|DRUG: ZN-c3
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasound-Guided Curved Needle Thread Carpal Tunnel Release: Efficacy and Safety of a Single-Center, Single-Arm Clinical Trial
Status: RECRUITING
Conditions: Carpal Tunnel Syndrome
Interventions: PROCEDURE: Loop Carpal Tunnel Release
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Muscular Strengthening for Paretic Knee Flexor and Extensor by Conventional Physiotherapy on Chronic Hemiplegic Stroke Patients
Status: COMPLETED
Conditions: Hemiplegia|Stroke
Interventions: PROCEDURE: Muscular Strengthening for paretic knee flexor and extensor|OTHER: conventional physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Safety Study of LY3372689 Given By Mouth to Healthy Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: LY3372689|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of MBG453 in Combination With Hypomethylating Agents in Subjects With IPSS-R Intermediate, High or Very High Risk Myelodysplastic Syndrome (MDS).
Status: COMPLETED
Conditions: Myelodysplastic Syndromes
Interventions: DRUG: MBG453|DRUG: Placebo|DRUG: Hypomethylating agents
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Catioprost® (Unpreserved Latanoprost 0.005% Emulsion) Compared to Travatan Z® to Treat Glaucoma and Ocular Surface Disease
Status: COMPLETED
Conditions: Glaucoma|Ocular Hypertension|Ocular Surface Disease
Interventions: DRUG: Latanoprost|DRUG: Travatan Z
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Development of IVF/ICSI Children Born From Different Endometrial Preparation Protocols
Status: RECRUITING
Conditions: Child Development|Endometrial Preparation
Interventions: DIAGNOSTIC_TEST: Developmental score according to The Ages & Stages Questionnaires®, Third Edition - ASQ®-3|OTHER: Physical development and General Health|DIAGNOSTIC_TEST: Developmental Red flags
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of 18F-fluciclovine (FACBC) PET/MR Uptake in Participants With Glioma
Status: COMPLETED
Conditions: Glioma
Interventions: DRUG: 18F-fluciclovine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Proof-of-concept Study for a New Intraocular Lens, MODEL C0001
Status: COMPLETED
Conditions: Cataract
Interventions: DEVICE: Model C0001|DEVICE: Model ZCB00
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Study With CIT-013 in RA Patients
Status: NOT_YET_RECRUITING
Conditions: Rheumatoid Arthritis
Interventions: DRUG: CIT-013 low dose|DRUG: CIT-013 high dose|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Unobtrusive Technologies for Monitoring of Autonomic Nervous System Function in Elderly Frail Patients
Status: COMPLETED
Conditions: Frailty|Autonomic Nervous System Imbalance
Interventions: OTHER: Home training program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The TIME-2b Study: A Study of AKB-9778 (Razuprotafib), a Novel Tie 2 Activator, in Patients With Non-Proliferative Diabetic Retinopathy (NPDR)
Status: COMPLETED
Conditions: Nonproliferative Diabetic Retinopathy
Interventions: DRUG: AKB-9778|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of a Peri-operative Brief Mindfulness-based Intervention on Post-operative Pain and Disability
Status: WITHDRAWN
Conditions: Chronic Hip Pain|Worries; Pain or Disability|Quality of Life
Interventions: BEHAVIORAL: Brief Mindfulness-Based Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Monoclonal Antibody Therapy, Cyclophosphamide, and Total-Body Irradiation Followed by Peripheral Stem Cell Transplantation in Treating Patients With Advanced Recurrent Acute Lymphocytic Leukemia
Status: COMPLETED
Conditions: Leukemia
Interventions: DRUG: cyclophosphamide|DRUG: methotrexate|PROCEDURE: allogeneic bone marrow transplantation|RADIATION: iodine I 131 monoclonal antibody BC8|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Comparison of Topical and Nebulized Anesthesia in Patients Undergoing Esophago-Gastro-Duodenoscopy
Status: UNKNOWN
Conditions: Anesthesia of Mucous Membrane
Interventions: DRUG: Lidocaine Spray|DRUG: Nebulized Lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Partially Blind Study to Evaluate Immunogenicity & Safety of GSK Bio's HPV Vaccine 580299 in Healthy Women Aged 9-25 Yrs
Status: COMPLETED
Conditions: Infections, Papillomavirus
Interventions: BIOLOGICAL: Cervarix|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Effect of Topical and Oral Diclofenac on Pain Related to Intravitreal Injections
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Diclofenac Eye Drops|DRUG: Pacebo pill|DRUG: Oral Diclofenac|DRUG: Diclofenac Eye Drops|DRUG: Pacebo pill|DRUG: Artificial Tears
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Intraoperative Noradrenaline to Control Arterial Pressure (INPRESS Study)
Status: COMPLETED
Conditions: Control of Arterial Blood Pressure
Interventions: OTHER: noradrenaline|OTHER: Ephedryne chorydrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A New Method for Identifying Sensory Changes in Painful Chemotherapy-induced Peripheral Neuropathy (CIPN)
Status: COMPLETED
Conditions: Chemotherapy-induced Peripheral Neuropathy
Interventions: OTHER: Brief Pain Inventory|OTHER: Hospital Anxiety and Depression Scale|OTHER: Neuropathic Pain Symptom Inventory|PROCEDURE: Diode Laser fiber type Selective Stimulator|PROCEDURE: Quantitative sensory testing|PROCEDURE: Conditioned pain modulation efficiency|OTHER: Spontaneous pain at baseline on 0-10 Numerical Rating Scale (NRS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Oral Ketone and Sodium Bicarbonate Administration During Endurance Exercise in Hypoxia
Status: COMPLETED
Conditions: Exercise|Hypoxia
Interventions: DIETARY_SUPPLEMENT: Ketone ester|OTHER: Sodium bicarbonate|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pretreatments of the Skin Prior to PDT
Status: COMPLETED
Conditions: Healthy
Interventions: PROCEDURE: Microneedle pretreatment + MAL-PDT|PROCEDURE: Sandpaper pretreatment + MAL-PDT|PROCEDURE: Curettage pretreatment + MAL-PDT|PROCEDURE: Ablative Fractional Laser (AFXL) pretreatment + MAL-PDT|PROCEDURE: Non-Ablative Fractional Laser (NAFXL) pretreatment + MAL-PDT|DRUG: MAL Control.|OTHER: Untreated Control
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cognitive Behavior Therapy for Insomnia: Analysis of Components, Mediators and Moderators
Status: COMPLETED
Conditions: Sleep Initiation and Maintenance Disorders
Interventions: BEHAVIORAL: Cognitive Therapy|BEHAVIORAL: Behavior Therapy|BEHAVIORAL: Waitlist.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pediatric ACL: Understanding Treatment Options
Status: ACTIVE_NOT_RECRUITING
Conditions: Anterior Cruciate Ligament Reconstruction
Interventions: OTHER: Non-operative treatment group will undergo standardized treatment which will include rehabilitation, bracing and certain activity restrictions|PROCEDURE: Surgical technique: Transphyseal reconstruction|PROCEDURE: Surgical technique: Partial transphyseal reconstruction|PROCEDURE: Surgical technique: Physeal sparing reconstruction by the Anderson method|PROCEDURE: Surgical technique: Physeal sparing reconstruction by the Micheli/Kocher method
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Recovery of Motor Skills With the Use of Artificial Intelligence and Computer Vision
Status: NOT_YET_RECRUITING
Conditions: Stroke|Hemiparesis|Spasticity as Sequela of Stroke|Dysmetria
Interventions: DEVICE: AssistI patients|DEVICE: Habilect patients
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acupuncture for Sedation in the Intensive Care Unit (ICU)
Status: COMPLETED
Conditions: Delirium|Respiratory Depression|Overmedication
Interventions: DEVICE: Verum Acupuncture|DEVICE: Sham Acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Intralesional Hyaluronic Acid and Verapamil Injection in Peyronie's Disease
Status: NOT_YET_RECRUITING
Conditions: Peyronie's Disease|Hyaluronic Acid|Verapamil
Interventions: DRUG: Intralesional treatment with Hyaluronic acid|DRUG: Intralesional treatment with Verapamil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Continuous Adductor Canal Block in Fast Track Total Knee Arthroplasty
Status: RECRUITING
Conditions: Total Knee Arthroplasty
Interventions: DRUG: continuous adductor canal block (CACB) ropivacaine|DRUG: sham continuous adductor canal block - ShACB NaCl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Test the Safety and Feasibility of Nivolumab With Drug Eluting Bead Transarterial Chemoembolization in Patients With Liver Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Liver Cancer
Interventions: DRUG: Drug Eluting Bead Transarterial Chemoembolization|DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antibiotic Prophylaxis for HDR Brachytherapy in the Treatment of Prostate Cancer
Status: SUSPENDED
Conditions: Prostate Cancer
Interventions: DRUG: Ciprofloxacin|DRUG: Cefazolin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Vecam 40/300 and Vecam 20/300 Compared to Omeprazole 20 mg on Gastric pH
Status: COMPLETED
Conditions: Gastroesophageal Reflux
Interventions: DRUG: Omeprazole|DRUG: Vecam|DRUG: Vecam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Antibiotic Prophylactic Protocols in Preterm Premature Rupture of the Membranes
Status: UNKNOWN
Conditions: Premature Rupture of Membrane
Interventions: DRUG: I.V cefuroxime 750 mg*3/d for 2 days|DRUG: I.V ampicillin 2 gram x4/d for 2 days|DRUG: P.O cefuroxime 500 mgx2/d for 5 days|DRUG: P.O roxithromycin 150 mg*2/d for 7 days|DRUG: P.O moxypen 500 mgx3/d for 5 days
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Genexol-PM Versus Paclitaxel in Anthracycline-pretreated Metastatic Breast Cancer Patients
Status: WITHDRAWN
Conditions: Breast Cancer
Interventions: DRUG: Genexol-PM|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Polysomnographic Study of Single-Dose Gabapentin in Transient Insomnia Induced by a Sleep Phase Advance
Status: COMPLETED
Conditions: Transient Insomnia
Interventions: DRUG: Gabapentin|DRUG: Gabapentin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Possible Protective Role of Omeprazole Against Oxaliplatin Induced Neuropathy in Cancer Patients
Status: NOT_YET_RECRUITING
Conditions: Chemotherapy Induced Peripheral Neuropathy
Interventions: DRUG: Omeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Tesetaxel as First-line Therapy for Metastatic Breast Cancer
Status: UNKNOWN
Conditions: Breast Neoplasm
Interventions: DRUG: Tesetaxel once every 3 weeks|DRUG: Tesetaxel once weekly
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation Of Needle-based Confocal Laser Endomicroscopy in Cystic Tumors of the Pancreas
Status: UNKNOWN
Conditions: Cystic Tumors of Pancreas
Interventions: DIAGNOSTIC_TEST: nCLE
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Sorafenib Tosylate and Chemotherapy in Treating Older Patients With Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Acute Myeloid Leukemia With FLT3/ITD Mutation|Acute Myeloid Leukemia With Inv(16)(p13.1q22) or t(16;16)(p13.1;q22); CBFB-MYH11|Acute Myeloid Leukemia With t(8;21); (q22; q22.1); RUNX1-RUNX1T1|Acute Promyelocytic Leukemia With PML-RARA|FLT3 Gene Mutation|Therapy-Related Acute Myeloid Leukemia
Interventions: PROCEDURE: Biopsy|PROCEDURE: Bone Marrow Aspiration|DRUG: Cytarabine|DRUG: Daunorubicin Hydrochloride|OTHER: Laboratory Biomarker Analysis|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration|DRUG: Sorafenib Tosylate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Dose-Finding Study of Pertuzumab (Perjeta) in Combination With Trastuzumab (Herceptin) in Healthy Male Participants and Women With Early Breast Cancer (EBC)
Status: COMPLETED
Conditions: Early Breast Cancer
Interventions: DRUG: Trastuzumab|DRUG: Pertuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacodynamic Evaluation of Switching From Prasugrel to Ticagrelor
Status: COMPLETED
Conditions: Coronary Artery Disease|Acute Coronary Syndrome
Interventions: DRUG: Ticagrelor 180mg|DRUG: Prasugrel 10mg|DRUG: Ticagrelor 90mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long-term Effect of an Health Education Program on Daily Physical Activity in Patients With Moderate to Very Severe Chronic Obstructive Pulmonary Disease
Status: RECRUITING
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: OTHER: Health education program|OTHER: Conventional management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Integration of Telemedicine and Home-Based Cardiac Rehabilitation: Feasibility, Efficacy, and Adherence
Status: RECRUITING
Conditions: Myocardial Infarction|Percutaneous Transluminal Coronary Angioplasty|Coronary Artery Bypass|Stable Angina|Heart Failure|Valve Disease, Heart|Cardiac Rehabilitation|Stent
Interventions: DEVICE: ROMTech Portable Connect
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Patient Care Management Strategies for Severe Heart Failure in Rhône-Alpes, France.
Status: COMPLETED
Conditions: Severe Heart Failure
Interventions: OTHER: PRETICARD patient care management|OTHER: "As usual " patient care management
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Development of Non-invasive Prenatal Test for Microdeletion and Other Genetic Syndromes Based on Cell Free DNA
Status: COMPLETED
Conditions: Microdeletion Syndromes|Trisomy 21|Trisomy 18|Trisomy 13|Sex Chromosome Abnormalities
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Dose-Reduced Allogeneic Stem Cell Transplantation After Autologous High-Dose Chemotherapy in Patients With Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma|Stem Cell Transplantation
Interventions: PROCEDURE: allogeneic hematopoietic SCT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Exercise Plus Pain Neuroscience Education on Brain Function in Knee Osteoarthritis
Status: NOT_YET_RECRUITING
Conditions: Knee Osteoarthritis
Interventions: OTHER: Neuromuscular exercise plus pain neuroscience education|OTHER: Neuromuscular exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Expanded Access Study of Satraplatin Plus Prednisone in Patients With Hormone Refractory Prostate Cancer (HRPC)
Status: TERMINATED
Conditions: Prostate Cancer
Interventions: DRUG: Oral Satraplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: QT Changes as Detected From LINQ ECG During and After Antiarrhythmic Loading (LINQ QT)
Status: RECRUITING
Conditions: Atrial Arrhythmia|QT Interval, Variation in|Arrhythmias, Cardiac
Interventions: DEVICE: LINQ/LINQ II
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Efficacy of Licaminlimab Ophthalmic Suspension for the Treatment of Dry Eye Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Dry Eye Disease
Interventions: DRUG: licaminlimab|OTHER: vehicle of OCS-02
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Black Tea on Vascular Function
Status: COMPLETED
Conditions: Vascular Function
Interventions: OTHER: Black tea extract|OTHER: Positive control|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE