pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Novel Imaging Based Quantitative Model-aided Detection of Portal Hypertension in Patients With Cirrhosis (CHESS2104)
Status: NOT_YET_RECRUITING
Conditions: Portal Hypertension
Interventions: DIAGNOSTIC_TEST: CT|DIAGNOSTIC_TEST: MRI|DIAGNOSTIC_TEST: HVPG|DIAGNOSTIC_TEST: Ultrasound
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Photoacoustic Endoscopy of Barrett's Esophagus
Status: COMPLETED
Conditions: Barrett Esophagus
Interventions: PROCEDURE: Photoacoustic endoscopy|PROCEDURE: Endoscopic ultrasound (standard of care)|PROCEDURE: Endoscopic surgery (standard of care)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation of Analgesia by PENG Block Versus Intra-Articular Infiltration in Prosthetic Hip Surgery (API)
Status: UNKNOWN
Conditions: Hip Prosthesis|Analgesia|PENG Block
Interventions: PROCEDURE: Prosthetic hip surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Comparison of The Effects of Thiazolidinediones(TZD), Sodium- Glucose Cotransporter 2 Inhibitors(SGLT2i) Alone and TZD / SGLT2i Combination Therapy on Non-alcoholic Fatty Liver Disease in Type 2 Diabetic Patients With Fatty Liver
Status: UNKNOWN
Conditions: NAFLD - Nonalcoholic Fatty Liver Disease|Type2 Diabetes
Interventions: DRUG: Pioglitazone|DRUG: Empagliflozin|DRUG: Combination of pioglitazone and empagliflozin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Real Time MRI Fused to Cone Beam CT Guided Biopsies of the Prostate.
Status: UNKNOWN
Conditions: Prostate Cancer
Interventions: PROCEDURE: CT Fusion + Transrectal U/S Guided Prostate Biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of How CagriSema Works on Appetite in People With Excess Body Weight
Status: RECRUITING
Conditions: Overweight|Obesity
Interventions: OTHER: No treatment given|DRUG: Cagrilintide and Semaglutide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of 5% Lidocaine Medicated Plaster on Allodynic Symptoms of Localized Neuropathic Pain After Knee Surgery
Status: COMPLETED
Conditions: Allodynic Symptoms|Localized Neuropathic Pain
Interventions: DRUG: Lidocaine|OTHER: placebo plaster
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Preterm DElayed Cord Clamping and Early Skin-to-Skin Contact: PreDECESS
Status: RECRUITING
Conditions: Bonding|Stress|Breastfeeding|Child Development|Adverse Events
Interventions: PROCEDURE: Delayed cord clamping and early skin-to-skin contact
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Everolimus and Alemtuzumab in Treating Patients With Recurrent Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma
Status: COMPLETED
Conditions: Lymphocytic Leukemia
Interventions: DRUG: alemtuzumab|DRUG: everolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TMC278-TiDP38-C145: A Bioavailability Study in Healthy Adult Volunteers to Evaluate 3 Pediatric Formulations of TMC278 (a Solution, a Suspension, and Granules) Compared to an Adult Tablet Formulation
Status: COMPLETED
Conditions: Pharmacokinetics|Bioavailability|HIV-1
Interventions: DRUG: TMC278
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tamoxifen and SUBA-Itraconzole Combination Testing in Ovarian Cancer
Status: RECRUITING
Conditions: Ovarian Cancer
Interventions: DRUG: SUBA-itraconazole|DRUG: Tamoxifen
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nitric Oxide Therapy for COVID-19 Patients With Oxygen Requirement
Status: COMPLETED
Conditions: Hypoxemia|Pneumonia, Viral|Coronavirus Infection
Interventions: DRUG: Nitric Oxide-Sessions|DRUG: Nitric Oxide-Continuous and Sessions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of a Postpartum Training Program on Women Who Have Suffered a Levator Ani Injury.
Status: RECRUITING
Conditions: Pelvic Floor Disorders|Pelvic Floor; Perineal Rupture, Obstetric|Physiotherapy
Interventions: OTHER: Physiotherapy treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Evaluation of the Pharmacokinetics, Safety and Tolerability of Single Dose of PF-06480605 in Chinese Healthy Participants
Status: COMPLETED
Conditions: Inflammatory Bowel Disease
Interventions: DRUG: 450mg|DRUG: 150mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Efficacy of Pharmacological Treatment of Working Memory Impairment After Traumatic Brain Injury: Evaluation With fMRI
Status: UNKNOWN
Conditions: Traumatic Brain Injury|Severe Traumatic Brain Injury
Interventions: DRUG: Modafinil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Administration of a Lactobacillus GG and Vitamins Containing Mixture is Effective in Preventing Nosocomial Infection in Children
Status: COMPLETED
Conditions: Nosocomial Infection
Interventions: DIETARY_SUPPLEMENT: Lactobacillus Rhamnosus GG|DIETARY_SUPPLEMENT: PLACEBO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Automated Oxygen Administration in Patients With Hypoxemic Pneumonia and Pleuropneumonia
Status: RECRUITING
Conditions: Pneumonia|Pneumonia, Ventilator-Associated|Length of Stay
Interventions: DEVICE: O2 automated|DEVICE: O2 standard
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Music on Inflammatory Response During Laparoscopic Surgery
Status: UNKNOWN
Conditions: Laparoscopy
Interventions: OTHER: music|OTHER: No music|PROCEDURE: Laparoscopic Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: EFFECTS OF CORE STRENGTHENING WITH RESISTIVE VERSUS NON-RESISTIVE DIAPHRAGMATIC TRAINING ON CORE ENDURANCE IN LOWER CROSS SYNDROME
Status: RECRUITING
Conditions: Lower Cross Syndrome
Interventions: PROCEDURE: Core Strengthening|PROCEDURE: Self-Diaphragm breathing exercises|PROCEDURE: Resistive-Diaphragm breathing exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Post Isometric Relaxation With and Without Stretching Exercises on Neck Pain and Muscle Spasm
Status: COMPLETED
Conditions: Neck Pain|Muscle Spasm
Interventions: OTHER: Traditional Physical Therapy|OTHER: Post Isometric Relaxation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Non-Damaging Photothermal Therapy of Non-exudative Age Related Macular Degeneration
Status: COMPLETED
Conditions: Macular Degeneration|Retinal Drusen
Interventions: DEVICE: Pascal Retinal Laser Photocoagulator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Immediate Effects of Spinal Manipulative Therapy on Kinetic and Kinematic Symmetry.
Status: COMPLETED
Conditions: Asymptomatic Condition
Interventions: PROCEDURE: Spinal Manipulative Therapy|PROCEDURE: SHAM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Using an Artificial Pancreas System in Older Adult Type 1 Diabetes Mellitus Patients
Status: TERMINATED
Conditions: Type1 Diabetes Mellitus
Interventions: DEVICE: CL/AP system|DEVICE: usual diabetic care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: FROST 4: Study of the Optimal Spreading of a Coronary Stent Guided With Pressure Into the Coronary Arteries
Status: COMPLETED
Conditions: Coronary Artery Insufficiency
Interventions: PROCEDURE: Intra coronary measures of pressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Histamine Dihydrochloride and Interleukin-2 in Primary Resectable Pancreatic Cancer
Status: NOT_YET_RECRUITING
Conditions: Pancreatic Cancer|Surgery|Metastasis|Immunosuppression
Interventions: DRUG: Histamine Dihydrochloride (HDC)|DRUG: Interleukin-2 (IL-2)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acceptability Among Children and Caregivers of Amylase Porridges
Status: COMPLETED
Conditions: Malnutrition
Interventions: DIETARY_SUPPLEMENT: CSB drum dried + α-amylase|DIETARY_SUPPLEMENT: CSB + α-amylase|DIETARY_SUPPLEMENT: RSB + α-amylase|DIETARY_SUPPLEMENT: WSB + α-amylase|DIETARY_SUPPLEMENT: CSB PLUS drum dried + α-amylase|DIETARY_SUPPLEMENT: CSB PLUS + α-amylase|DIETARY_SUPPLEMENT: RSB PLUS + α-amylase|DIETARY_SUPPLEMENT: WSB PLUS + α-amylase|DIETARY_SUPPLEMENT: Commercial porridge flour|DIETARY_SUPPLEMENT: Commercial porridge bar|DIETARY_SUPPLEMENT: Commercial MSB + α-amylase
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Immunogenicity and Safety of Fluzone® Quadrivalent, Southern Hemisphere 2015 Formulation (Intramuscular Route)
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Fluzone Quadrivalent Influenza Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Low-dose Dasiglucagon for Prevention of Insulin-Induced Hypoglycemia in People With Type 1 Diabetes
Status: COMPLETED
Conditions: Type 1 Diabetes|Hypoglycemia
Interventions: DRUG: Dasiglucagon|OTHER: Carbohydrate (dextrose tablets)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Steroids Versus ECP and Steroids as First-line Treatment of Grade II Acute GVHD
Status: NOT_YET_RECRUITING
Conditions: Graft Vs Host Disease
Interventions: DRUG: Uvadex|DRUG: Steroids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BAY1003803 Single and Multiple Dose Escalation, Safety, Tolerability and Pharmacokinetics Study
Status: TERMINATED
Conditions: Psoriasis
Interventions: DRUG: BAY1003803 0.01% lipophilic cream|DRUG: BAY1003803 0.1% lipophilic cream|DRUG: BAY1003803 0.01% ointment|DRUG: BAY1003803 0.1% ointment|DRUG: Lipophilic cream vehicle|DRUG: Ointment vehicle|DRUG: Clobetasol propionate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: "Death Rattle" - A Double Blind, Randomly Controlled, Crossover Trial
Status: TERMINATED
Conditions: Noise|Death
Interventions: DRUG: Atropine Sulphate 1% ophthalmic drops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Unravelling Targets of Therapy in Bronchial Thermoplasty in Severe Asthma
Status: COMPLETED
Conditions: Asthma|Bronchial Asthma
Interventions: PROCEDURE: Bronchial thermoplasty|DEVICE: Alair system (Boston Scientific, USA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Bioavailability of EPA + DHA Enriched Canned Tuna and Its Acute Effects
Status: UNKNOWN
Conditions: Healthy Volunteers
Interventions: DIETARY_SUPPLEMENT: Meal containing canned tuna + fish oil (5 g EPA + DHA)|DIETARY_SUPPLEMENT: Meal containing canned tuna + soybean oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Low Dose Daunorubicin in Pediatric Relapsed/Refractory Acute Leukemia
Status: COMPLETED
Conditions: Relapsed Pediatric ALL|Relapsed Pediatric AML|Refractory Acute Myeloid Leukemia|Refractory Acute Lymphoblastic Leukemia
Interventions: DRUG: Daunorubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Curcumin in Reducing Joint Pain in Breast Cancer Survivors With Aromatase Inhibitor-Induced Joint Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer|Joint Pain
Interventions: DIETARY_SUPPLEMENT: Curcumin|OTHER: Placebo|OTHER: Nanoemulsion|OTHER: Quality-of-Life Assessment|BEHAVIORAL: Questionnaire
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Traumeel S for Reduction of Post Operative Pain Following Arthroscopy
Status: SUSPENDED
Conditions: Post-operative Pain
Interventions: DRUG: Traumeel S: intra-operative irrigation + oral ingestion|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial for the Surgical Treatment of Elderly Distal Radius Fractures
Status: COMPLETED
Conditions: Distal Radius Fracture
Interventions: PROCEDURE: Open Reduction and Internal Fixation|PROCEDURE: External Fixation|PROCEDURE: Percutaneous Pinning|PROCEDURE: Closed Reduction and casting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Pharmacokinetics of Quisinostat, a Histone Deacetylase Inhibitor, in Combination With Chemotherapy
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer|Epithelial Ovarian Cancer
Interventions: DRUG: Quisinostat|DRUG: Paclitaxel|DRUG: Carboplatin|DRUG: Gemcitabine|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study of Locally Advanced Pancreatic Cancer
Status: UNKNOWN
Conditions: Pancreatic Cancer
Interventions: DRUG: ICT of oxapliplatin, irinotecan, leucovorin, and fluorouracil and CCRT|DRUG: ICT of Gemcitabine,oxapliplatin, leucovorin, and fluorouracil + CCRT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial Evaluating the Efficacy and Safety of Tenecteplase Together With Unfractionated Heparin Prior to Early Percutaneous Coronary Intervention (PCI) as Compared to Standard Primary PCI in Patients With Acute Myocardial Infarction (ASSENT 4 PCI)
Status: TERMINATED
Conditions: Myocardial Infarction
Interventions: DRUG: Tenecteplase|PROCEDURE: PCI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of M2ES in Patients With Advanced Pancreatic Cancer After Gemcitabine Treatment Failure
Status: UNKNOWN
Conditions: Pancreatic Cancer
Interventions: DRUG: M2ES|DRUG: M2ES|DRUG: M2ES|DRUG: M2ES 60mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of MK0859 in Patients With Primary Hypercholesterolemia or Mixed Hyperlipidemia (MK-0859-011)(COMPLETED)
Status: COMPLETED
Conditions: Hypercholesterolemia|Hyperlipidemia
Interventions: DRUG: MK0859
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Mechanisms of Choroidal Blood Flow Changes During Dark/Light Transitions
Status: COMPLETED
Conditions: Regional Blood Flow|Ocular Physiology
Interventions: DRUG: Phenylephrine|DRUG: NG-Monomethyl-L-Arginine|DRUG: Propanolol|DRUG: Atropine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Randomized Controlled Trial for Wheat Oral Immunotherapy
Status: RECRUITING
Conditions: Allergy;Food|Wheat Allergy|Children
Interventions: OTHER: Wheat-containing food
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Efinopegdutide (MK-6024) in Participants With Nonalcoholic Fatty Liver Disease (NAFLD) (MK-6024-001)
Status: COMPLETED
Conditions: Nonalcoholic Fatty Liver Disease|Nonalcoholic Steatohepatitis
Interventions: DRUG: Efinopegdutide 20 mg/mL|DRUG: Semaglutide 1.34 mg/mL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Post Operative Pain Control After Pediatric Hip Surgery
Status: TERMINATED
Conditions: Hip Surgery|Post Operative Pain Control
Interventions: PROCEDURE: Lumbar Plexus Catheter|PROCEDURE: Lumbar Epidural Catheter|PROCEDURE: Patient Controlled Analgesia|DRUG: Fentanyl|DRUG: Morphine|DRUG: Lorazepam|DRUG: Ondansetron|DRUG: Diphenhydramine|DRUG: Acetaminophen|DRUG: Oxycodone|DRUG: Ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Lebrikizumab (RO5490255) in Participants With Severe Oral Corticosteroids (OCS) Dependent Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Lebrikizumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Roflumilast on Airway Blood Flow as an Expression of Airway Inflammation in COPD
Status: COMPLETED
Conditions: COPD
Interventions: DRUG: Roflumilast Placebo|DRUG: Roflumilast
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Ascending Dose Study of BMS-986259 to Study Safety in Healthy Participants
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DRUG: BMS-986259|OTHER: Placebo|DIAGNOSTIC_TEST: P-Aminohippurate|DIAGNOSTIC_TEST: Iohexol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Sorafenib vs.TransArterial Chemoembolization Plus RadioTherapy in Hepatocellular Carcinoma With Macrovascular Invasion
Status: COMPLETED
Conditions: Hepatocellular Carcinoma
Interventions: RADIATION: TACE+External beam RT|DRUG: Sorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Collaborative cOMMUNIty Care for Metastatic breAsT cancEr Patients in inDonesia (Communicated)
Status: NOT_YET_RECRUITING
Conditions: Metastatic Breast Cancer|Cancer
Interventions: OTHER: Health education for cadre (communicated project)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Perioperative Erector Spinae Plane Block in Thoracoscopic Surgery
Status: UNKNOWN
Conditions: Pain, Postoperative|Regional Block
Interventions: PROCEDURE: erector spinae plane block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Growth of Infants Fed Hydrolysate Formulas
Status: COMPLETED
Conditions: Growth and Tolerance
Interventions: OTHER: RTF Infant Formula|OTHER: Powder Infant Formula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Ventricular Arrhythmia After Myocarditis in Sportsman
Status: UNKNOWN
Conditions: Myocarditis Acute|Ventricular Arrythmia
Interventions: DIAGNOSTIC_TEST: Treadmill Stress test
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Utilizing the Crosstalk Among Aerosolized Phenformin , Methylene Blue, Photodynamic Therapy , Zinc and Potassium for Treating Severe COVID-19 Infection and Its Inflammatory Complication
Status: UNKNOWN
Conditions: COVID-19
Interventions: COMBINATION_PRODUCT: Combination therapy plus Standard therapy|RADIATION: Photodynamic therapy|DRUG: Standard therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Dietary and Life Style Modification on Post Liver Transplant Obesity
Status: TERMINATED
Conditions: Post Liver Transplantation Weight Gain|Post Liver Transplantation Obesity|Nonalcoholic Steatohepatitis
Interventions: BEHAVIORAL: Dietary and life style modification
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Intradialytic Exercises in Chronic Kidney Disease Patients
Status: COMPLETED
Conditions: Chronic Kidney Disease stage3
Interventions: DEVICE: leg pedaling cycling device|DEVICE: sand bags|DEVICE: hemodialysis sessions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pegfilgrastim PBPC Mobilization Study
Status: COMPLETED
Conditions: Lymphoma|Hodgkin's Lymphoma|Non-Hodgkin's Lymphoma|Hematology|Oncology
Interventions: DRUG: pegfilgrastim 12 mg|DRUG: filgrastim|DRUG: pegfilgrastim 6 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Gulf War Illness Inflammation Reduction Trial
Status: COMPLETED
Conditions: Chronic Inflammation|Chronic Pain|Fatigue|Cognitive Impairment
Interventions: DRUG: Modified-Release Prednisone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tolerance, Safety, and Activity of Rifapentine Alone and in Combination Therapy in AIDS Patients With Mycobacterium Avium Complex Bacteremia.
Status: COMPLETED
Conditions: Mycobacterium Avium-Intracellulare Infection|HIV Infections
Interventions: DRUG: Rifapentine|DRUG: Ethambutol hydrochloride|DRUG: Clarithromycin|DRUG: Azithromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Pilot Study of the Living With Hope Program for Family Caregivers of Persons With Dementia Residing in Long Term Care
Status: COMPLETED
Conditions: Dementia
Interventions: BEHAVIORAL: Living with Hope Program|BEHAVIORAL: Stories of the Present
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Remifentanil Plus Ketamine for Dynamic Flexible Bronchoscopy
Status: WITHDRAWN
Conditions: Bronchoscopy
Interventions: DRUG: Remifentanil|DRUG: Fentanyl|DRUG: Midazolam|DRUG: Ketamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Assessment of an Oral Influenza B Vaccine Tablet (VXA-BYW.10) Following Single Dose Administration in Healthy Adults
Status: COMPLETED
Conditions: Seasonal Influenza B
Interventions: BIOLOGICAL: VXA-BYW.10 (Low Dose) Oral Vaccine|BIOLOGICAL: VXA-BYW.10 (High Dose) Oral Vaccine|OTHER: Placebo Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Trial Comparing Three Strategies of Vaccination Against the Virus of Hepatitis B in HIV Infected Patients
Status: COMPLETED
Conditions: HIV Infections
Interventions: BIOLOGICAL: GenHevac B Pasteur|BIOLOGICAL: GenHevac B Pasteur|BIOLOGICAL: GenHevac B Pasteur
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Escalation of Daratumumab Frequency Following Biochemical Progression in Relapsed/Refractory Multiple Myeloma
Status: WITHDRAWN
Conditions: Multiple Myeloma
Interventions: BIOLOGICAL: Dara-SC|PROCEDURE: Blood for research assessments|PROCEDURE: Bone marrow for research assessments
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lenalidomide, Dexamethasone, and Clarithromycin in Treating Patients Who Have Undergone Stem Cell Transplant for Multiple Myeloma
Status: COMPLETED
Conditions: DS Stage I Plasma Cell Myeloma|DS Stage II Plasma Cell Myeloma|DS Stage III Plasma Cell Myeloma|Refractory Plasma Cell Myeloma
Interventions: DRUG: Clarithromycin|DRUG: Dexamethasone|DRUG: Lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Allogeneic Transplantation From Related Haploidentical Donors
Status: COMPLETED
Conditions: Blood Cancer|Leukemia|Graft Versus Host Disease|Malignancy|CLL|NHL|Hodgkin's Disease|MDS
Interventions: PROCEDURE: non-myeloablative hematopoietic cell transplantation|DRUG: Anti-Thymocyte Globulin|DRUG: Cyclosporine|DRUG: Mycophenolate Mofetil|DRUG: G-CSF|DRUG: Solumedrol|DRUG: Acetaminophen|DRUG: Diphenydramine|DRUG: Hydrocortisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Neuromuscular Electrical Stimulation in Patients With Chronic Low Back Pain
Status: COMPLETED
Conditions: Low Back Pain|Paraspinal Muscles
Interventions: DEVICE: StimaWell 120MTRS system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study of the Efficacy and Safety PF-06741086 in Adult and Teenage Participants With Severe Hemophilia A or Moderately Severe to Severe Hemophilia B
Status: ACTIVE_NOT_RECRUITING
Conditions: Hemophilia A|Hemophilia B
Interventions: DRUG: PF-06741086
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Preoperative Information to Parents Before Ear-nose-throat Pediatric Surgery
Status: COMPLETED
Conditions: Anxiety|Consumer Satisfaction
Interventions: BEHAVIORAL: Specific information brochure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Clinical Evaluation of DAILIES TOTAL 1® Performance in a Japanese Population
Status: COMPLETED
Conditions: Refractive Error
Interventions: DEVICE: Delefilcon A contact lenses|DEVICE: Narafilcon A contact lenses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Cipralex in Treatment of Depressive Symptoms and Chronic Back Pain
Status: WITHDRAWN
Conditions: Low Back Pain|Depression
Interventions: DRUG: Escitalopram|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Proximal Lower Limb Intramuscular Block : Effects on Hemiparetic Gait
Status: UNKNOWN
Conditions: Neurologic Disorder|Spastic Hemiplegia|Gait, Hemiplegic|Block
Interventions: DRUG: Ropivacaine injection|DRUG: Sodium Chloride Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Salt Intake, Microbiota, Immune Response and Endothelial Function in Hypertension
Status: UNKNOWN
Conditions: Hypertension
Interventions: DIETARY_SUPPLEMENT: Low salt diet plus sodium chloride supplements|DIETARY_SUPPLEMENT: Low salt diet plus placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Bedside Ultrasound in the Assessment of Deep Venous Thrombosis: Effectiveness of In-Person Versus Online Instruction
Status: COMPLETED
Conditions: Deep Vein Thrombosis|Pulmonary Embolism
Interventions: OTHER: Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: DIAGNOSTIC
Clinical trial: Presurgical Phase II Study of Talazoparib in Combination With Enzalutamide in Prostate Cancer
Status: NOT_YET_RECRUITING
Conditions: Prostate Cancer
Interventions: DRUG: ADT|DRUG: Enzalutamide|DRUG: Talazoparib|DRUG: Degarelix|DRUG: Luprolide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized, Double-blind, Placebo-controlled Study of ZSP1601 in Adult Subjects With Nonalcoholic Steatohepatitis (NASH)
Status: RECRUITING
Conditions: Nonalcoholic Steatohepatitis (NASH)
Interventions: DRUG: ZSP1601|DRUG: ZSP1601|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Nutritional Adequacy Therapeutic Enhancement in the Critically Ill. The NUTRIATE Study
Status: TERMINATED
Conditions: Gastroparesis
Interventions: DRUG: GSK962040 50 mg|DRUG: Metoclopramide 10 mg|DRUG: Placebo NG|DRUG: Placebo IV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Antimicrobial Photodynamic Therapy on Periodontal Treatment and Salivary Status of Type 1 Diabetes Mellitus Patients
Status: TERMINATED
Conditions: Diabetes Mellitus, Type 1|Periodontal Diseases|Periodontal Pocket
Interventions: PROCEDURE: Scaling root planing|PROCEDURE: Antimicrobial photodynamic therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: HIV Risk Reduction in Youth in the Bahamas
Status: COMPLETED
Conditions: HIV Infections
Interventions: BEHAVIORAL: FOYC|BEHAVIORAL: Goal for it (GFI)|BEHAVIORAL: Wonderous Wetlands|BEHAVIORAL: Caribbean Informed Parents and Children Together (CImPACT)|BEHAVIORAL: Bahamian Focus on Older Youth (BFOOY)|BEHAVIORAL: Health and Family Life Curriculum (HFLE)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Glycerol, Two Topical Steroids, and a Topical Immune Modulator Against Skin Irritation
Status: UNKNOWN
Conditions: Dermatitis, Contact|Dermatitis, Occupational
Interventions: DRUG: clobetasol|DRUG: triamcinolone acetonide|DRUG: tacrolimus|DRUG: glycerol|DRUG: vehicle ointment (paraffin oil/soft white paraffin)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Viscosupplementation of Hyaluronic Acid With Addition of Lecithin in Patients With Mild or Moderate Osteoarthrosis of the Knee Joint.
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: DEVICE: Intra-articular injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Surgical Treatment of Osteoarticular Infections Using Bioactive Bone Substitute
Status: NOT_YET_RECRUITING
Conditions: Osteomyelitis|Infections|Fracture|Antibiotics
Interventions: PROCEDURE: OSTEOMYELITIS SURGICAL TREATMENT WITH LOCAL ANTIBIOTICS AND PEROSSAL
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Flublok v. Standard Dose Vaccine Effectiveness Among Kaiser Permanente Northern California Adults 18-64 Years
Status: COMPLETED
Conditions: Influenza|Pneumonia|Lower Respiratory Tract Infection|Acute Myocardial Infarction|Congestive Heart Failure|Stroke
Interventions: BIOLOGICAL: Flublok Quadrivalent|BIOLOGICAL: Standard Dose Inactivated Influenza Vaccine (SD-IIV)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Cholesterol-lowering Effects of Lupin Protein
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DIETARY_SUPPLEMENT: Protein drink - low dosage|DIETARY_SUPPLEMENT: Protein drink - high dosage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Phase I Study of GW856553 (Losmapimod)
Status: COMPLETED
Conditions: Acute Coronary Syndrome
Interventions: DRUG: Losmapimod for single dose|DRUG: Losmapimod for repeat dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Clinical Efficacy Study of Salmeterol Xinafoate/Fluticasone Propionate in Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: OT329 (combination of fluticasone propionate and salmeterol xinafoate)|DRUG: Advair Diskus (combination of fluticasone propionate and salmeterol xinafoate)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Theca Cell Function in Adolescents With Polycystic Ovary Syndrome (PCOS)
Status: COMPLETED
Conditions: PCOS
Interventions: DRUG: Dexamethasone|DRUG: recombinant human chorionic gonadotropin (r-hCG)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety and Efficacy of ZP-Zolmitriptan Intracutaneous Microneedle Systems for the Acute Treatment of Migraine
Status: COMPLETED
Conditions: Acute Migraine
Interventions: DRUG: ZP-Zolmitriptan|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Youth-focused Strategies to Promote Adherence to Pre-exposure Prophylaxis Among Youth At-risk for HIV in Thailand
Status: COMPLETED
Conditions: Adherence, Medication|Adolescent Behavior|HIV Prevention|Sexual Health|Mobile Health
Interventions: BEHAVIORAL: 'Project Raincoat' Mobile Phone Application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Phase II Trial of Epirubicin, Oxaliplatin and Capecitabine (EOX) Versus Docetaxel and Oxaliplatin (ElTax) in the Treatment of Advanced Gastro-oesophageal Cancer
Status: COMPLETED
Conditions: Gastro Oesophageal Cancer
Interventions: DRUG: Epirubicin|DRUG: Oxaliplatin|DRUG: Capecitabine|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Open Label, Randomized Study of Neoadjuvant Nivolumab and Chemotherapy, With or Without Sub-ablative Stereotactic Body Radiation Therapy, for Resectable Stage IIA to IIIB Non-small Cell Lung Cancer
Status: RECRUITING
Conditions: Resectable Stage IIA to IIIB Non-small Cell Lung Cancer
Interventions: DRUG: Nivolumab|RADIATION: (8gy x 3)|DRUG: Platinum Doublet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Avastin (Bevacizumab) in Combination With Herceptin (Trastuzumab)/Docetaxel in Patients With HER2 Positive Metastatic Breast Cancer.
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: bevacizumab [Avastin]|DRUG: Docetaxel|DRUG: Herceptin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Impact of L- Carnitine in Intradialytic Hypotension in Pediatric Patients on Regular Hemodialysis
Status: ACTIVE_NOT_RECRUITING
Conditions: Intradialytic Hypotension
Interventions: DRUG: L Carnitine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Heparin-free Extracorporeal Membrane Oxygenation Support During Clinical Lung Transplantation
Status: RECRUITING
Conditions: Lung Transplantation
Interventions: DRUG: Heparin sodium|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of e-Cigarettes on Perceptions and Behavior - Remote Substudy # 2
Status: COMPLETED
Conditions: Electronic Cigarette Use|Cigarette Smoking|Cigarette Use, Electronic|Vaping
Interventions: OTHER: E-cigarette
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Efficacy and Safety Study of Methylphenidate Hydrochloride Extended Release in Adults With Childhood-onset Attention Deficit/Hyperactivity Disorder (ADHD)
Status: COMPLETED
Conditions: Attention Deficit/Hyperactivity Disorder
Interventions: DRUG: Placebo|DRUG: Ritalin LA 20 mg|DRUG: Ritalin LA 30 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trastuzumab and Irinotecan in Treating Patients With HER2/Neu Positive Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: BIOLOGICAL: trastuzumab|DRUG: irinotecan hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Everolimus Therapy in People With Birt-Hogg-Dube Syndrome (BHD)-Associated Kidney Cancer or Sporadic Chromophobe Renal Cancer
Status: TERMINATED
Conditions: Renal Cancer|Birt-Hogg-Dube Syndrome
Interventions: DRUG: Everolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Repetitive Transcranial Magnetic Stimulation as a Treatment for Tinnitus
Status: UNKNOWN
Conditions: Tinnitus
Interventions: DEVICE: Active rTMS 1|DEVICE: Active rTMS 2|DEVICE: Active rTMS 3|DEVICE: sham condition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tafasitamab + Lenalidomide + R-CHOP Versus R-CHOP in Newly Diagnosed High-intermediate and High Risk DLBCL Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Diffuse Large B-cell Lymphoma
Interventions: DRUG: Tafasitamab|DRUG: Lenalidomide|DRUG: Rituximab|DRUG: Cyclophosphamide|DRUG: Doxorubicin|DRUG: Vincristine|DRUG: Prednisone|DRUG: Tafasitamab placebo|DRUG: Lenalidomide placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: How to Optimally Train Emotional and Social Skills
Status: NOT_YET_RECRUITING
Conditions: Mental Health
Interventions: BEHAVIORAL: Emotion regulation|BEHAVIORAL: Self-acceptance|BEHAVIORAL: Mindfulness|BEHAVIORAL: Resource activation|BEHAVIORAL: Control component 1_social behaviors in groups|BEHAVIORAL: Control component 2_communication skills|BEHAVIORAL: Control component 3_stress management|BEHAVIORAL: Control component 4_constructive conflict resolution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy of Talampanel in Glioblastoma Multiforme
Status: COMPLETED
Conditions: Glioblastoma Multiforme
Interventions: DRUG: Talampanel|RADIATION: Radiation Therapy (RT) 5 days a week +|DRUG: temozolomide(TMZ) 75mg|DRUG: adjuvant TMZ 200mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cotrimoxazole Prophylaxis in Severely Malnourished Children
Status: COMPLETED
Conditions: Nutrition Disorders|Life-threatening Infection
Interventions: DRUG: Cotrimoxazole dispersible tablet|DRUG: Placebo dispersible tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Single Patient Protocol: A Phase II Study Using the Administration of Autologous T-Cells Genetically Engineered to Express T-Cell Receptors Reactive Against Mutated Neoantigens in a Patient With Metastatic Cancer Plus the Administration of Pembrolizumab
Status: NO_LONGER_AVAILABLE
Interventions: BIOLOGICAL: Individual Patient TCR Transduced PBL|DRUG: Cyclophosphamide|DRUG: Fludarabine|DRUG: Aldesleukin|DRUG: Pembrolizumab
Study Type: EXPANDED_ACCESS
Clinical trial: Pilot Study of Rituximab for the Treatment of Acute Immune Thrombocytopenic Purpura (ITP)
Status: COMPLETED
Conditions: Purpura, Thrombocytopenic, Idiopathic
Interventions: DRUG: Rituximab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: LifeFlow Fluid Study- Non- Critical Pediatric Patients Having a Trans Abdominal Ultrasound
Status: COMPLETED
Conditions: Dehydration in Children|Dehydration
Interventions: DEVICE: LifeFlow
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Acute Hemostasis Following the Use of the AQUABEAM® System for the Treatment of Benign Prostatic Hyperplasia II
Status: COMPLETED
Conditions: Benign Prostatic Hyperplasia
Interventions: DEVICE: AquaBeam System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial to Learn if REGV131-LNP1265 is Safe and Works to Help the Body Make Clotting Factor in Pediatric, Adolescent and Adult Patients With Hemophilia B
Status: NOT_YET_RECRUITING
Conditions: Hemophilia B
Interventions: DRUG: REGV131|DRUG: LNP1265
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Repeat Intravenous Infusions of B4T2-001 CAR-T Without Lymphodepleting Chemotherapy for Solid Tumors
Status: RECRUITING
Conditions: Advanced Solid Tumor
Interventions: BIOLOGICAL: B4T2-001 autologous CAR-T
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of MVA85A Prime and Bacille Calmette-Guerin Boost Vaccination
Status: COMPLETED
Conditions: Tuberculosis|HIV
Interventions: BIOLOGICAL: MVA85A|BIOLOGICAL: Candin|BIOLOGICAL: BCG Vaccine SSI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of SHC014748M in Patients With Relapsed or Refractory Follicular (FL) or Marginal Zone (MZL) Lymphoma
Status: UNKNOWN
Conditions: Follicular Lymphoma(FL)|Marginal Zone Lymphoma(MZL)
Interventions: DRUG: SHC014748M
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of Rituximab Versus Mycophenolate Mofetil (MMF) in Participants With Pemphigus Vulgaris (PV)
Status: COMPLETED
Conditions: Pemphigus Vulgaris
Interventions: DRUG: Mycophenolate Mofetil Placebo|DRUG: Mycophenolate Mofetil|DRUG: Rituximab|DRUG: Rituximab Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Imatinib Mesylate, Busulfan, Fludarabine, and Antithymocyte Globulin for CML Patients
Status: TERMINATED
Conditions: Leukemia
Interventions: DRUG: Imatinib Mesylate|DRUG: Fludarabine (Fludara)|DRUG: Busulfan|DRUG: Antithymocyte Globulin (ATG)|DRUG: Tacrolimus|DRUG: Methotrexate|PROCEDURE: Donor lymphocyte infusion (DLI)|PROCEDURE: Stem Cell Transplant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial Examining Cellular Energetics Related to Various Wound Treatment Therapies
Status: TERMINATED
Conditions: Diabetic Foot Ulcers
Interventions: DEVICE: Powered Suction Pump (VAC Freedom)|DEVICE: Powered Suction Pump|DEVICE: MWT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE