pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: T1-mapping by Cardiovascular Magnetic Resonance Imaging to Assess Non-Alcoholic Fatty Liver Disease
Status: UNKNOWN
Conditions: NAFLD|Heart Failure|Valvular Disease|Coronary Disease
Interventions: DIAGNOSTIC_TEST: T1 mapping on Cardiovascular Magnetic Resonance Studies
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: HELICOBACTER PYLORI INFECTION IN TYPE 2 DIABETES MELLITUS IN ASSIUT UNIVERSITY HOSPITAL
Status: NOT_YET_RECRUITING
Conditions: H Pylori Infection
Interventions: DIAGNOSTIC_TEST: ALL PATIENT DIABETIC IN THIS PERIOD WILL BE INCLUDED IN THE STUDY
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Combination Chemotherapy, Monoclonal Antibody, and Radiation Therapy in Treating Patients With Primary Central Nervous System Lymphoma
Status: COMPLETED
Conditions: Brain and Central Nervous System Tumors|Lymphoma
Interventions: DRUG: rituximab|DRUG: methotrexate|DRUG: temozolomide 100 mg/m^2|DRUG: temozolomide 150 mg/m^2|DRUG: temozolomide 200 mg/m^2|RADIATION: radiation therapy|DRUG: post-radiation therapy temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of AIN457 in Patients With Active Non-infectious Uveitis
Status: TERMINATED
Conditions: Uveitis
Interventions: DRUG: AIN457|DRUG: AIN457|DRUG: AIN457|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Development and Evaluation of Sleep Intervention for Perinatal Family
Status: NOT_YET_RECRUITING
Conditions: Sleep|Psychological Distress|Perinatal Problems
Interventions: BEHAVIORAL: sleep intervention|BEHAVIORAL: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Corneal Confocal Microscopy in Patients With Type 1 Diabetes
Status: WITHDRAWN
Conditions: Diabetic Neuropathies
Interventions: DEVICE: Corneal confocal microscopy|PROCEDURE: Skin biopsy|PROCEDURE: Nerve conduction study|OTHER: Blood draw
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: An Exercise Intervention for Prostate Cancer Patients Receiving Androgen Deprivation Therapy
Status: COMPLETED
Conditions: Prostate Cancer|Physical Activity|Side-effects
Interventions: BEHAVIORAL: Supervised and Home Based Exercise|BEHAVIORAL: Stretching Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Randomized, Double-blind, Placebo-controlled Study to Evaluate the Effect of Roflumilast on Endothelial Function in Patients With Chronic Obstructive Pulmonary Disease
Status: UNKNOWN
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Roflumilast 500|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Explorative Trial Evaluating the Efficacy and Tolerability of LEO43204 in Moderate to Severe Acne
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: LEO43204|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Infrared Transillumination of the Front of the Neck
Status: COMPLETED
Conditions: Tracheal Intubation
Interventions: PROCEDURE: Tracheal intubation by endoscopy with flexible bronchoscope
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Laparoscopic Complete Mesocolic Excision on Colon Cancer
Status: COMPLETED
Conditions: Operation Finding|Complications|Pathology|Quality of Life|Neoplasms Recurrence
Interventions: PROCEDURE: laparoscopic complete mesocolic excision|PROCEDURE: D3-laparoscopic colectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Videolaryngoscopy vs. Direct Laryngoscopy for Elective Airway Management in Pediatric Anesthesia
Status: COMPLETED
Conditions: Tracheal Intubation Morbidity
Interventions: DEVICE: Videolaryngoscopy|DEVICE: Direct laryngoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Feasibility and Safety Study of the Automated Insulin Delivery Closed Loop System Pancreas4ALL
Status: UNKNOWN
Conditions: Type 1 Diabetes
Interventions: DEVICE: Pancreas4ALL - meal announcement or full closed loop
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Testing Response Bias on Sensitive Topics in Self- Versus Enumerator-administered Surveys
Status: RECRUITING
Conditions: Bias, Implicit
Interventions: BEHAVIORAL: Self-administered survey|BEHAVIORAL: Enumerator-administered survey
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Safety of SG001 Combined With PLD in Patients With Platinum-resistant Relapsed EOC
Status: UNKNOWN
Conditions: Epithelial Ovarian Cancer|Fallopian Tube Cancer|Peritoneal Cancer
Interventions: DRUG: SG001|DRUG: Doxorubicin hydrochloride liposome injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Challenge of the Nasopharynx With Neisseria Lactamica Expressing the Meningococcal Protein Neisseria Adhesin A (NadA)
Status: COMPLETED
Conditions: Meningitis, Bacterial|Neisseria Infection
Interventions: BIOLOGICAL: N. lactamica
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Clinical Trial of Adsorbed Cell-free DPT Vaccine (5-component) (for People Aged 6 Years and Above)
Status: RECRUITING
Conditions: Diphtheria|Tetanus|Pertussis
Interventions: BIOLOGICAL: Tetanus, Reduced Diphtheria and Acellular Pertussis (Five Components) Combined Vaccine, Adsorbed (Aged 6 Years and Older) (Tdcp)|BIOLOGICAL: 23-Valent Pneumococcal Polysaccharide Vaccine（PPV23）|BIOLOGICAL: Diphtheria and Tetanus Combined Vaccine, Adsorbed (DT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Hypohydration and Cardiorespiratory Function
Status: COMPLETED
Conditions: Dehydration
Interventions: DIETARY_SUPPLEMENT: Carbohydrate|DIETARY_SUPPLEMENT: Carbohydrate protein|DIETARY_SUPPLEMENT: Starved
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Evaluate Finerenone on Clinical Efficacy and Safety in Patients With Heart Failure Who Are Intolerant or Not Eligible for Treatment With Steroidal Mineralocorticoid Receptor Antagonists
Status: NOT_YET_RECRUITING
Conditions: Heart Failure
Interventions: DRUG: Finerenone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Open-label Extension Trial of Cannabidiol (GWP42003-P, CBD) for Seizures in Tuberous Sclerosis Complex (GWPCARE6)
Status: COMPLETED
Conditions: Tuberous Sclerosis Complex|Seizures
Interventions: DRUG: GWP42003-P
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Bioequivalence Study of Capecitabine Tablets
Status: COMPLETED
Conditions: Metastatic Breast Cancer or Metastatic Colorectal Cancer
Interventions: DRUG: Capecitabine tablets|DRUG: XELODA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study on the Effect of Eye-covering Pretreatment on Acute Delirium After General Anesthesia in Pre-school Aged Children
Status: UNKNOWN
Conditions: Ophthalmology
Interventions: BEHAVIORAL: To explore whether pretreatment with eye covering can reduce the incidence of acute delirium and the score of delirium after general anesthesia in ophthalmology pre-age children.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of D-allulose on the Glycemic Changes in Patients With Type 2 Diabetes Mellitus During Ramadan Fasting
Status: COMPLETED
Conditions: Glucose, High Blood
Interventions: OTHER: Control period|DIETARY_SUPPLEMENT: D-allulose period
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 12 Week Evaluation of the Safety and Efficacy of 3 Doses of CP-526,555 and Placebo for Smoking Cessation
Status: COMPLETED
Conditions: Smoking Cessation
Interventions: DRUG: CP-526,555 (varenicline)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Study on the Effect of Cilostazol in Patients With Chronic Tinnitus
Status: COMPLETED
Conditions: Tinnitus
Interventions: DRUG: Cilostazol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Long-term Consequences of Neuroimaging and Perceived Cognitive Dysfunction in oPRES
Status: UNKNOWN
Conditions: Neuroimaging|Cognitive Dysfunction|Posterior Reversible Encephalopathy Syndrome
Interventions: BIOLOGICAL: neuroimaging examination,neuro-cognitive test,blood pressure,blood sample
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Efficacy Study of Novel Gene Therapy ZM-02 for Retinitis Pigmentosa Patients
Status: RECRUITING
Conditions: Retinitis Pigmentosa
Interventions: DRUG: ZM-02-L|DRUG: ZM-02-H|PROCEDURE: ZM-02-S
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Antibiotic Treatment for Infections of Short Term In-dwelling Vascular Catheters Due to Gram Positive Bacteria
Status: COMPLETED
Conditions: Bacterial Infections|Gram-Positive Bacterial Infections|Bacteremia
Interventions: DRUG: Linezolid|DRUG: Vancomycin|DRUG: Oxacillin|DRUG: Dicloxacillin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Staccato Fentanyl Single and Multidose PK
Status: COMPLETED
Conditions: Breakthrough Pain
Interventions: DRUG: Inhaled Placebo|DRUG: Inhaled Fentanyl 25 mcg|DRUG: Intravenous Fentanyl 25 mcg|DRUG: Inhaled Fentanyl 25 mcg x 2|DRUG: Inhaled Fentanyl 25 mcg x 4|DRUG: Inhaled Fentanyl 25 mcg x 6|DRUG: Inhaled Fentanyl 25 mcg x 12
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Posterior and Anterior Approach to Sacrospinous Ligament Apical Fixation - Randomized Controlled Trial
Status: RECRUITING
Conditions: Pelvic Organ Prolapse|Surgical Procedure, Unspecified
Interventions: PROCEDURE: Apical prolapse fixation - anterior access|PROCEDURE: Apical prolapse fixation - posterior access
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endovascular Management of Direct Carotid-cavernous Fistula
Status: RECRUITING
Conditions: Carotid-Cavernous Sinus Fistula
Interventions: PROCEDURE: Endovascular management of direct carotid-cavernous fistula
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reducing Metabolic Dysregulation in Obese Latina Breast Cancer Survivors Using Physical Activity
Status: RECRUITING
Conditions: Breast Cancer|Coronary Artery Disease|Stroke|Type2 Diabetes
Interventions: BEHAVIORAL: Progressive combine training (PCT)|BEHAVIORAL: Attention Control (AC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Follow-up Study of the Effectiveness of Virtual Reality Therapy in MS Patients
Status: COMPLETED
Conditions: Multiple Sclerosis, Chronic Progressive|Multiple Sclerosis, Primary Progressive
Interventions: OTHER: Training groupe|OTHER: PNF|OTHER: Spinning grp|OTHER: Balance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Rifaximin Delayed Release for the Prevention of Recurrent Acute Diverticulitis and Diverticular Complications.
Status: TERMINATED
Conditions: Diverticulitis
Interventions: DRUG: Rifaximin delayed released 400mg Tablet|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety, Tolerability,Pharmacokinetics and Pharmacodynamics of ODM-106 in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteer Study
Interventions: DRUG: ODM-106|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Dose, Safety, Tolerability and Immunogenicity of an Influenza H10 Stabilized Stem Ferritin Vaccine, VRC-FLUNPF0103-00-VP, in Healthy Adults
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: VRC-FLUNPF0103-00-VP (H10ssF-6473)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: To Evaluate the Efficacy and Safety of SHR0302 Tablet in Subjects of Active Psoriatic Arthritis
Status: ENROLLING_BY_INVITATION
Conditions: Psoriatic Arthritis
Interventions: DRUG: SHR0302 tablets、Placebo|DRUG: SHR0302 tablets、Placebo|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Home Based Swallowing Exercise in Stroke Patients With Dysphagia
Status: NOT_YET_RECRUITING
Conditions: Dysphagia Following Cerebrovascular Accident
Interventions: BEHAVIORAL: home based IOPI swallow training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Exercise Programs on Gait in Children With Scoliosis Diagnosed JIA
Status: RECRUITING
Conditions: Scoliosis Idiopathic|Juvenile Idiopathic Arthritis|Gait, Frontal
Interventions: OTHER: Conventional exercises|OTHER: 3D exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Study To Evaluate The Safety Of Apixaban In Atrial Fibrillation
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DRUG: Apixaban|DRUG: Apixaban|DRUG: Warfarin sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Posterior Vitreous Detachment (PVD) Assessment During Dual Retinal Vein Occlusion (RVO) Lucentis Evaluations
Status: COMPLETED
Conditions: Retinal Vein Occlusion|Posterior Vitreous Detachment
Interventions: DRUG: Ranibizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Temozolomide and O6-benzylguanine in Treating Children With Solid Tumors
Status: COMPLETED
Conditions: Brain and Central Nervous System Tumors|Childhood Germ Cell Tumor|Extragonadal Germ Cell Tumor|Kidney Cancer|Liver Cancer|Neuroblastoma|Ovarian Cancer|Sarcoma|Unspecified Childhood Solid Tumor, Protocol Specific
Interventions: DRUG: O6-benzylguanine|DRUG: temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Intravenous Magnesium Sulfate in Aneurysmal Subarachnoid Haemorrhage (IMASH)
Status: COMPLETED
Conditions: Subarachnoid Hemorrhage
Interventions: DRUG: Intravenous magnesium sulfate infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: --SuPERIOR Trial--
Status: NOT_YET_RECRUITING
Conditions: Non-Small Cell Lung Cancer (NSCLC)|Clinical Staging T2b-3 N0-1 M0
Interventions: DRUG: Durvalumab|RADIATION: Non-ablative oligofractionated radiation (NORT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Supervised Center-based vs. Unsupervised Home-based Exercise Programs (PRO-Training)
Status: RECRUITING
Conditions: Physical Inactivity|Healthy|Older Adult
Interventions: BEHAVIORAL: Unsupervised home-based exercise group without motivational intervention (UNSUP)|BEHAVIORAL: Unsupervised home-based exercise group with motivational intervention (UNSUP+)|BEHAVIORAL: Supervised center-based exercise group without motivational intervention (SUP)|BEHAVIORAL: Supervised center-based exercise group with motivational intervention (SUP+)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of BC-DN-01 in Painful Diabetic Peripheral Neuropathy
Status: WITHDRAWN
Conditions: Diabetic Neuropathy, Painful
Interventions: DRUG: BC-DN-01 topically applied cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prime-boost Vaccine Study in Women With Low-grade Cervical HPV Lesions
Status: COMPLETED
Conditions: HPV Infection|CIN1
Interventions: BIOLOGICAL: ChAdOx1-HPV|BIOLOGICAL: MVA-HPV|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Castleman Disease Collaborative Network Biobank
Status: WITHDRAWN
Conditions: Castleman Disease|Castleman's Disease|Giant Lymph Node Hyperplasia|Angiofollicular Lymph Hyperplasia|Angiofollicular Lymph Node Hyperplasia|Angiofollicular Lymphoid Hyperplasia|GLNH|Hyperplasia|Giant Lymph Node
Interventions: OTHER: Sample Collection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Occupational Therapy and Home Exercises for Adults With Operatively Treated Distal Radius Fractures
Status: COMPLETED
Conditions: Distal Radius Fractures
Interventions: OTHER: Independent Excercises|OTHER: Occupational Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Topical Treatment With Clonidine + Pentoxifylline in Patients With Neuropathic Pain
Status: TERMINATED
Conditions: Neuralgia Peripheral
Interventions: DRUG: Topical Solution|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nuedexta in the Treatment of Pseudobulbar Affect in Patients With Alzheimer's Disease
Status: TERMINATED
Conditions: Alzheimer's Disease|Pseudobulbar Affect (PBA)
Interventions: DRUG: Nuedexta (20/10)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Autologous Fecal Microbiota Transplantation (Auto-FMT) for Prophylaxis of Clostridium Difficile Infection in Recipients of Allogeneic Hematopoietic Stem Cell Transplantation
Status: ACTIVE_NOT_RECRUITING
Conditions: Allogeneic Hematopoietic Stem Cell
Interventions: BIOLOGICAL: fecal microbiota transplantation (FMT)|OTHER: No fecal microbiota transplantation (FMT), routine management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: NWP09 in Children With Attention Deficit Hyperactivity Disorder (ADHD)
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: DRUG: NWP09|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pancreatic Nutritional Program for Weight Loss in Overweight/Obese Patients With Stage I-III Breast Cancer
Status: COMPLETED
Conditions: Obesity|Stage IA Breast Cancer|Stage IB Breast Cancer|Stage IIA Breast Cancer|Stage IIB Breast Cancer|Stage IIIA Breast Cancer|Stage IIIB Breast Cancer|Stage IIIC Breast Cancer
Interventions: DIETARY_SUPPLEMENT: Dietary Intervention|OTHER: Educational Intervention|OTHER: Laboratory Biomarker Analysis|OTHER: Quality-of-Life Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparative Study Between Intravascular Ultrasonography Guided and Angiography-guided Recanalization of Coronary Chronic Total Occlusions
Status: UNKNOWN
Conditions: Coronary Occlusion
Interventions: DEVICE: intravascular ultrasonography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Safety of Artemether - Lumefantrine, and Other Malaria Drugs and Their Effect on the Auditory Function
Status: TERMINATED
Conditions: Malaria|Falciparum
Interventions: DRUG: Artemether-lumefantrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Ocrelizumab on Cerebrospinal Fluid Biomarkers at Multiple Sclerosis Onset
Status: ACTIVE_NOT_RECRUITING
Conditions: Relapsing Multiple Sclerosis|Clinically Isolated Syndrome
Interventions: DRUG: Ocrelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of the Association of Berberine Fitosoma® and Monacolin K MonaKoPure® on Glyco-metabolic Parameters in Dysglycemic and Dyslipidemic Patients.
Status: RECRUITING
Conditions: Dyslipidemias|Dysglycemia
Interventions: DIETARY_SUPPLEMENT: Berberol® K|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Outcomes Associated With Progressive Balance And Gait Training Using The KineAssist® Robot
Status: COMPLETED
Conditions: Cerebrovascular Accident
Interventions: BEHAVIORAL: Balance Task Training with therapist guarding support|BEHAVIORAL: Balance task training with robotic guarding support|BEHAVIORAL: Challneged balance task training with robotic guarding support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cuff Shape and Postoperative Sore Throat in Breast Cancer Patients
Status: NOT_YET_RECRUITING
Conditions: Breast Cancer|Postoperative Sore Throat|Subglottic Airway Injury|Endotracheal Tube Cuff
Interventions: DEVICE: Tapered-shaped cuff tracheal tube|DEVICE: Cylindrical-shaped cuff tracheal tube
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Describe the Safety and Immunogenicity of a Respiratory Syncytial Virus Vaccine IN006 in Healthy Adults
Status: NOT_YET_RECRUITING
Conditions: Respiratory Syncytial Virus Infections
Interventions: BIOLOGICAL: Bivalent RSV Vaccine (IN006)|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Lumbrokinase for Long Covid Clinical Trial
Status: NOT_YET_RECRUITING
Conditions: Long Covid|Post-treatment Lyme Disease Syndrome|Chronic Fatigue Syndrome|Myalgic Encephalomyelitis
Interventions: DIETARY_SUPPLEMENT: Lumbrokinase
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity Study of the Western Equine Encephalitis (WEE) Vaccine
Status: UNKNOWN
Conditions: Western Equine Encephalitis
Interventions: BIOLOGICAL: Western Equine Encephalitis (WEE) Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Supernormal Oxygen Delivery for Elderly Surgical Patients
Status: UNKNOWN
Conditions: Femoral Fractures
Interventions: PROCEDURE: SV maximization|PROCEDURE: supernormal DO2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Intragastric pH Profile After 5 Days Pantoprazole 40 mg iv Followed by Oral Esomeprazole 40 mg po or Oral Pantoprazole 40 mg po
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Esomeprazole|DRUG: pantoprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Comparison of IN 10 003 to Placebo in Subjects With Insomnia Suffering From Difficulty in Falling Asleep and Staying Asleep
Status: COMPLETED
Conditions: Subjects With Insomnia Suffering From Difficulty in Falling Asleep and Staying Asleep
Interventions: DRUG: IN 10 003 formulation A|DRUG: IN 10 003 formulation B|DRUG: Placebo capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety of Overestimation of a Meal Insulin Bolus in the Context of Dual-hormone Closed-loop Operation - Part 2
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: OTHER: Dual-hormone closed-loop|DRUG: Insulin|DRUG: Glucagon|DEVICE: Dexcom G4 Platinum glucose sensor|DEVICE: Accu Chek Combo insulin pump
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Primary Peritoneal Carcinosis of Digestive Origin Using Cytoreductive Surgery and Hyperthermic Intraoperative Peritoneal Chemotherapy With Mitomycin C and Irinotecan
Status: COMPLETED
Conditions: Peritoneal Carcinosis (PC)
Interventions: PROCEDURE: cytoreductive surgery and HIPEC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Saphenous Nerve Radiofrequency for Knee Osteoarthritis Trial
Status: UNKNOWN
Conditions: Osteoarthritis, Knee
Interventions: PROCEDURE: Saphenous Nerve|PROCEDURE: Genicular nerves
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Aliskiren and Losartan on Peritoneal Membrane in Continuous Ambulatory Peritoneal Dialysis Patients
Status: UNKNOWN
Conditions: Peritoneal Membrane Failure
Interventions: DRUG: placebo|DRUG: Aliskiren|DRUG: Aliskiren plus Losartan|DRUG: Enalapril plus Losartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Color Doppler Ultrasound in Lacrimal Sac Space-occupying Lesions
Status: COMPLETED
Conditions: Dacryocystitis; Chronic|Lacrimal Sac Space-occupying Lesions|Color Doppler Ultrasound|Computed Tomography
Interventions: OTHER: CDU and CT-DCG or CT examination
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Concurrent Surgery for Prolapse and Stress Urinary Incontinence to Reduce Further Surgery for Incontinence
Status: NOT_YET_RECRUITING
Conditions: Stress Urinary Incontinence
Interventions: PROCEDURE: anti incontinence surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Carbo/Paclitaxel Followed by Doxorubicin/Cyclophosphamide in Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer|Triple Negative Breast Cancer
Interventions: DRUG: Carboplatin|DRUG: Paclitaxel|DRUG: Doxorubicin|DRUG: Cyclophosphamide|DRUG: Pegfilgrastim|DRUG: Filgrastim
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non-invasive Stimulation of Brain Networks and Cognition in Alzheimer's Disease and Frontotemporal Dementia
Status: COMPLETED
Conditions: Alzheimer's Disease|Frontotemporal Dementia, Behavioral Variant
Interventions: DEVICE: transcranial direct current stimulation (tDCS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Role of ChatGPT in Educating Patients With Early-stage Hepatocellular Carcinoma
Status: RECRUITING
Conditions: Carcinoma, Hepatocellular
Interventions: BEHAVIORAL: ChatGPT|BEHAVIORAL: patient education with traditional methods.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Evaluation of [18F]APN-1607 PET Uptake in Alzheimer's Disease Patients Compared With Healthy Subjects
Status: ACTIVE_NOT_RECRUITING
Conditions: Alzheimer's Disease|Mild Cognitive Impairment Due to Alzheimer's Disease|Healthy Volunteers
Interventions: DRUG: [18F]APN-1607
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Neuroendocrine Tumors - Patient Reported Outcomes
Status: ENROLLING_BY_INVITATION
Conditions: Neuroendocrine Tumors|Gastroenteropancreatic Neuroendocrine Tumor|Lung Neuroendocrine Neoplasm|Neuroendocrine Carcinoma
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Chronic Pain on Delay Discounting in Methadone Patients
Status: TERMINATED
Conditions: Opioid-use Disorder|Chronic Pain Syndrome
Interventions: DRUG: Naloxone Hydrochloride|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Magnetic Resonance (MR) Guided Functional Ultrasound-Neurosurgery for Movement Disorders
Status: COMPLETED
Conditions: Essential Tremor|Dystonia|Parkinson's Disease
Interventions: DEVICE: Non-invasive intervention with focused ultrasound (ExAblate 4000)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Placebo Controlled, Randomized, Double-blind, Multi-center Study to Investigate the Efficacy and Tolerability of BAY58-2667
Status: TERMINATED
Conditions: Congestive Heart Failure
Interventions: DRUG: Placebo|DRUG: Cinaciguat (BAY58-2667)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SafeHeal Colovac Colorectal Anastomosis Protection Device Evaluation (SAFE-2) Pivotal Study
Status: TERMINATED
Conditions: Colorectal Cancer|Rectal Cancer|Rectal Tumor|Rectal/Anal
Interventions: DEVICE: Colovac|PROCEDURE: Stoma Creation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bronchoscopy in Determining the Effect of E-Cigarette Smoking on Biomarkers in the Lungs
Status: RECRUITING
Conditions: Cigarette Smoker|Current Every Day Smoker
Interventions: PROCEDURE: Bronchoscopy with Bronchoalveolar Lavage|DRUG: Cigarette|OTHER: Electronic Cigarette|OTHER: Electronic Cigarette|OTHER: Laboratory Biomarker Analysis|DRUG: Nicotine Replacement|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Phase IV-Pharmacovigilance Study of Keppra Greece - S.K.A.T.E.: Safety of Keppra as Adjunctive Therapy in Epilepsy
Status: COMPLETED
Conditions: Epilepsy
Interventions: DRUG: Levetiracetam (Keppra)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Toripalimab Plus Pemetrexed+Platinus in Advanced Non-small-cell Lungcancer Patients Previsouly Treated EGFR-TKI
Status: RECRUITING
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: TORIPALIMAB INJECTION(JS001 )
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Collaborative Open Research Initiative Study (CORIS-1)
Status: NOT_YET_RECRUITING
Conditions: Patient Engagement|COVID-19|Preventable Disease, Vaccine|Burnout, Professional|Emerging Infectious Disease|Artificial Intelligence|Climate Change|Online Education|Mental Health Issue|Substance Use Disorders
Interventions: OTHER: No intervention. This is an observational study
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Cold Water Immersion Modulates Reinforcing Effects of Nitrous Oxide - 2
Status: COMPLETED
Conditions: Opioid-Related Disorders|Substance-Related Disorders
Interventions: DRUG: 0% N2O|DRUG: 40% N2O
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Fourth Dose of Human Papillomavirus (HPV) DNA Plasmid (VGX-3100) + EP in Adult Females Previously Vaccinated With Three Doses of VGX-3100
Status: COMPLETED
Conditions: Human Papillomavirus (HPV)
Interventions: BIOLOGICAL: VGX-3100
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Predictive Markers in Chinese Growth Hormone Deficiency (GHD) Children Treated With Saizen®
Status: COMPLETED
Conditions: Dwarfism, Pituitary
Interventions: DRUG: Recombinant human growth hormone (r-hGH)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Ritonavir-Boosted Danoprevir in Combination With Pegasys (Peginterferon Alfa-2a) and Copegus (Ribavirin) in Patients of Asian Origin With Chronic Hepatitis C Genotype 1 With or Without Cirrhosis
Status: COMPLETED
Conditions: Hepatitis C, Chronic
Interventions: DRUG: danoprevir + ritonavir|DRUG: danoprevir + ritonavir|DRUG: peginterferon alfa-2a [Pegasys]|DRUG: peginterferon alfa-2a [Pegasys]|DRUG: ribavirin [Copegus]|DRUG: ribavirin [Copegus]
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevalence of Pneumonia After Adding Repetitive Transcranial Magnetic Stimulation in Poststroke Dysphagia
Status: RECRUITING
Conditions: Stroke, Acute|Dysphagia|Pneumonia
Interventions: DEVICE: Repetitve transcranial magnetic stimulation|DEVICE: Sham transcranial magnetic stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Ibuprofen and Paracetamol Pharmacokinetic Study
Status: COMPLETED
Conditions: Healthy Volunteer Study
Interventions: DRUG: Ibuprofen Acid|DRUG: Ibuprofen Lysine|DRUG: Ibuprofen Sodium|DRUG: Ibuprofen Liquid Capsules|DRUG: Paracetamol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Clinical Trial of the PfSPZ Vaccine
Status: COMPLETED
Conditions: Plasmodium Falciparum
Interventions: BIOLOGICAL: Plasmodium falciparum Sporozoite (strain NF-54; Anopheles stephensi mosquitoes) Vaccine, Live, Inactivated (gamma irradiation)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Influences of Watching a Movie Clip of Normal Walking on Measurable Walking Parameters Among Post-Brain-Stroke Patients as Opposed to the Influences of a Control Movie Clip Showing Backwards Walking
Status: UNKNOWN
Conditions: Stroke
Interventions: OTHER: watching a normal walking clip|OTHER: watching walk backward clip
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Application of IPC During Surgery to Prevent Venous Thrombosis in Gastrointestinal Surgery Patients.
Status: ACTIVE_NOT_RECRUITING
Conditions: Gastrointestinal Neoplasms|Stomach Neoplasms|Intestinal Neoplasms
Interventions: DEVICE: Intermittent Pneumatic Compression Devices
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Corticosteroid Effects on Asymptomatic Gadolinium-enhancing Lesions in Multiple Sclerosis
Status: UNKNOWN
Conditions: Multiple Sclerosis, Relapsing-Remitting|Magnetic Resonance Imaging|Methylprednisolone
Interventions: DRUG: Methylprednisolone succinate|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Olmesartan Medoxomil, Amlodipine and Hydrochlorothiazide Combination Therapy in Patients With Hypertension Not Controlled With Olmesartan Medoxomil and Hydrochlorothiazide Combination Therapy
Status: COMPLETED
Conditions: Essential Hypertension
Interventions: DRUG: CS8635 20/5/12.5mg and placebo|DRUG: Olmetec® Plus 20/12.5mg and placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Placebo-controlled Trial of Percutaneous Coronary Intervention for the Relief of Stable Angina
Status: COMPLETED
Conditions: Stable Angina
Interventions: PROCEDURE: Percutaneous coronary intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ultrasound-guided Injection of Glucocorticoid Into Infrapatellar Fat Pad in Patients With Knee Osteoarthritis
Status: UNKNOWN
Conditions: Osteoarthritis, Knee
Interventions: DRUG: Glucocorticoids|DRUG: Saline|DRUG: Hyaluronic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparative Clinical Study to Evaluate the Effectiveness of ProFlor vs. Lichtenstein for Inguinal Hernia Repair
Status: COMPLETED
Conditions: Inguinal Hernia
Interventions: DEVICE: ProFlor Hernia Repair System|DEVICE: Lichtenstein hernia repair
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of LY3556050 in Healthy Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: LY3556050|DRUG: Placebo|DRUG: Iohexol|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Phase II Study DCVAC/OvCa Plus Carboplatin Gemcitabine Relapsed Platinum (Pt)-Sensitive Epithelial Ovarian Carcinoma
Status: COMPLETED
Conditions: Ovarian Neoplasms|Ovarian Cancer (OvCa)|Ovarian Epithelial Cancer
Interventions: BIOLOGICAL: DCVAC/OvCa in parallel with chemotherapy|DRUG: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Infliximab in the Treatment of Patients Affected by Corticodependent Crohn's Disease (P02732)
Status: TERMINATED
Conditions: Crohn's Disease
Interventions: BIOLOGICAL: Infliximab|DRUG: AZA|DRUG: Placebo Prednisolone|DRUG: Prednisolone|DRUG: AZA|BIOLOGICAL: Placebo Infliximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Relative Bioavailability of Telmisartan and SR26334 After Co-administration Compared to the Bioavailability of Telmisartan and SR26334 After Administration of Telmisartan and Clopidogrel Alone in Healthy Male and Female Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Telmisartan|DRUG: Clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized, Double-blind, Placebo-controlled Phase 1 Study to Evaluate the Safety, Tolerability and Pharmacokinetics of JX2105 in Healthy Chinese Subjects
Status: ENROLLING_BY_INVITATION
Conditions: Parkinson's Disease
Interventions: DRUG: JX2105|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Enzalutamide and Decitabine in Treating Patients With Metastatic Castration Resistant Prostate Cancer
Status: WITHDRAWN
Conditions: Castration Levels of Testosterone|Castration-Resistant Prostate Carcinoma|Metastatic Prostate Carcinoma in the Soft Tissue|Prostate Carcinoma Metastatic in the Bone|PSA Level Greater Than or Equal to Two|PSA Progression|Stage IV Prostate Cancer AJCC v8|Stage IVA Prostate Cancer AJCC v8|Stage IVB Prostate Cancer AJCC v8
Interventions: DRUG: Decitabine|DRUG: Enzalutamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Increasing HCV Linkage to Care Among People Who Inject Drugs
Status: COMPLETED
Conditions: Hepatitis C
Interventions: OTHER: Simplified HCV care within a mobile medical unit
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Safety, Reactogenicity, and Immunogenicity Study of Heterologous Booster Vaccination of a SARS-CoV-2 Recombinant Protein Nanoparticle Vaccine (GBP510)
Status: ACTIVE_NOT_RECRUITING
Conditions: COVID-19 (Healthy Volunteers)
Interventions: BIOLOGICAL: SARS-CoV-2 Recombinant Protein Nanoparticle Vaccine (GBP510) (RBD of SARS-CoV-2 25ug / dose) Adjuvanted with AS03|OTHER: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Fatigue Alleviation Through Neuromodulating Therapy in Multiple Sclerosis
Status: NOT_YET_RECRUITING
Conditions: Multiple Sclerosis, Relapsing-Remitting|Fatigue
Interventions: DEVICE: Real Repetitive Transcranial Magnetic Stimulation|DEVICE: Sham Repetitive Transcranial Magnetic Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: UTOLA: UTerin OLAparib
Status: ACTIVE_NOT_RECRUITING
Conditions: Endometrial Carcinoma
Interventions: DRUG: Olaparib Oral Capsule|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Prevalence of Foot Complaints/Problems and Ulcers in a Pre-dialysis Population
Status: COMPLETED
Conditions: Foot Ulcer|Diabetes Mellitus|Chronic Kidney Diseases|Pre-dialysis
Interventions: OTHER: Pre-dialysis population
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: rTMS to Improve Cognition in Parkinson's
Status: RECRUITING
Conditions: Parkinson's Disease|Mild Cognitive Impairment
Interventions: DEVICE: MagVenture MagProX100 stimulator (MagVenture, Falun, Denmark)|DEVICE: MagVenture MagProX100 stimulator (MagVenture, Falun, Denmark)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hemodynamics and Extravascular Lung Water in Acute Lung Injury
Status: COMPLETED
Conditions: Acute Lung Injury
Interventions: DRUG: Diuresis (furosemide) part I|OTHER: Fluid Bolus (crystalloid or albumin)|OTHER: Fluid Bolus (crystalloid or albumin)|DRUG: Vasopressors (Norepinephrine, Vasopressin, Phenylephrine, Epinephrine)|DRUG: Vasopressors (Norepinephrine, Vasopressin, Phenylephrine, Epinephrine)|DRUG: Dobutamine|DRUG: Dobutamine|OTHER: Concentrate all drips and nutrition|DRUG: Diuresis (furosemide) part II|PROCEDURE: Dialysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT