pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Safety and Efficacy of PHP in the Treatment of Shock Associated With Systemic Inflammatory Response Syndrome (SIRS)
Status: COMPLETED
Conditions: Shock|Systemic Inflammatory Response Syndrome
Interventions: DRUG: pyridoxalated hemoglobin polyoxyethylene conjugate (PHP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: FLT-PET/DW-MRI for Detection of Brain Metastases and Early Therapy Evaluation in Patients With Small Cell Lung Cancer
Status: COMPLETED
Conditions: Small Cell Lung Cancer
Interventions: DEVICE: FLT-PET|DEVICE: MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Morphine Consumption in Joint Replacement Patients, With or Without Gabapentin Treatment
Status: COMPLETED
Conditions: Post Operative Pain|Total Knee Replacement
Interventions: DRUG: Gabapentin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Study of MKC-1 in Patients With Refractory Hematologic Malignancies
Status: COMPLETED
Conditions: Hematological Malignancies|Myelodysplasia|Agnogenic Myeloid Metaplasia
Interventions: DRUG: MKC-1
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SCREENING OF EPIGENETIC BIOMARKERS (miRNAs) IN THE GINGIVAL SULCUS
Status: UNKNOWN
Conditions: Periodontal Diseases|Inflammatory Response
Interventions: DIAGNOSTIC_TEST: Levels of epigenetic biomarkers present in the gingival fluid and its possible relationship with bone metabolism.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Efficacy of Nigella Sativa Oil Mouth Rinse in the Management of Recurrent Minor Aphthous Ulcer
Status: NOT_YET_RECRUITING
Conditions: Aphthous Ulcer
Interventions: OTHER: Nigella Sativa Oil Mouth Rinse|OTHER: isotonic (normal saline) with concentration 0.90% of sodium chloride (NaCl)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Psychoeducational Intervention Model to Improve Nutritional Status in Low Resource Settings
Status: COMPLETED
Conditions: Child Malnutrition|Child Overnutrition|Malnutrition in Children|Malnutrition, Child|Nutrition Disorders, Child|Malnutrition
Interventions: BEHAVIORAL: Psychoeducational intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Vorinostat on Nervous System Hemangioblastomas in Von Hippel-Lindau Disease (Missense Mutation Only)
Status: COMPLETED
Conditions: Von Hippel-Lindau Disease
Interventions: DRUG: Vorinostat
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Mirena® IUD's Effect on Fallopian Tube Fimbriae and Ovarian Cortical Inclusion Cyst Cell Proliferation
Status: COMPLETED
Conditions: Epithelial Ovarian Cancer
Interventions: DEVICE: Mirena® intra-uterine device (IUD)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Online Tailored Interventions & Relational Agents for Exercise and Sun Protection
Status: COMPLETED
Conditions: Sedentary|Skin Cancer
Interventions: OTHER: Tailored Internet Communication with Relational Agent|OTHER: Tailored Internet Communications
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Isotonic Saline for Children With Bronchiolitis
Status: NOT_YET_RECRUITING
Conditions: Bronchiolitis|Respiratory Disease|Asthma in Children|Viral Infection|Acute Respiratory Infection
Interventions: OTHER: Nebulized isotonic saline|OTHER: Nasal irrigation with isotonic saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Intrapleural Instillation of the Nivolumab in Cancer Patients With Pleural Effusion.
Status: COMPLETED
Conditions: Renal Cell Cancer Metastatic|Non-small Cell Lung Cancer Metastatic|Pleural Effusion, Malignant
Interventions: DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BPM31510 in Treating Patients With Recurrent High-Grade Glioma Previously Treated With Bevacizumab
Status: COMPLETED
Conditions: Gliosarcoma|Recurrent Glioblastoma|Astrocytoma of Brain|Glioblastoma
Interventions: OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacological Study|DRUG: Ubidecarenone Injectable Nanosuspension
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: LOcoregional vs Systemic Therapy in Patients With BCLC Stage B HCC
Status: RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Atezolizumab and bevacizumab|RADIATION: transarterial chemoembolization (TACE) or transarterial radioembolization (TARE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Nivolumab Combined With Ipilimumab Versus Nivolumab Alone in Participants With Advanced Kidney Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Renal Cell Carcinoma
Interventions: BIOLOGICAL: Nivolumab|BIOLOGICAL: Ipilimumab|OTHER: Ipilimumab placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Assessing the Efficacy and Safety of Sarilumab Added to MTX in Japanese Patients With Moderately to Severely Active Rheumatoid Arthritis (SARIL-RA-KAKEHASI)
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Sarilumab SAR153191 (REGN88)|OTHER: Placebo (for sarilumab)|DRUG: Methotrexate|DRUG: Folic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Group Cognitive Behavioral Therapy Versus Fluoxetine for Obsessive-Compulsive Disorder: a Practical Trial
Status: COMPLETED
Conditions: Obsessive Compulsive Disorder
Interventions: BEHAVIORAL: Group Cognitive Behavior Therapy|DRUG: SSRI (fluoxetine, sertraline, paroxetine, citalopram)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Dabrafenib in Treating Patients With Solid Tumors and Kidney or Liver Dysfunction
Status: TERMINATED
Conditions: BRAF Gene Mutation|Hepatic Complication|Renal Failure|Solid Neoplasm
Interventions: DRUG: Dabrafenib|OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacogenomic Study|OTHER: Pharmacological Study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Immuno-bridging Study of a Nonavalent HPV Vaccine (E.Coli) in Healthy Population Aged 9-17 vs Aged 18-26 Years Old
Status: ACTIVE_NOT_RECRUITING
Conditions: Cervical Cancer|Condylomata Acuminata
Interventions: BIOLOGICAL: 3 doses of the Recombinant Human Papillomavirus Nonavalent (Types 6,11,16,18,31,33,45,52,58 )Vaccine(E.Coli)|BIOLOGICAL: 2 doses of theRecombinant Human Papillomavirus Nonavalent (Types 6,11,16,18,31,33,45,52,58 )Vaccine(E.Coli)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of Standard CHOP Versus Biweekly CHOP in Aggressive Non-Hodgkin's Lymphoma (JCOG9809)
Status: TERMINATED
Conditions: Non-Hodgkin's Lymphoma
Interventions: DRUG: Standard CHOP|DRUG: Bi-CHOP (dose intensified CHOP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Decrease Fatigue With Light Therapy
Status: COMPLETED
Conditions: Hodgkin Lymphoma|Diffuse Large B Cell Lymphoma
Interventions: DEVICE: Light therapy intensity 1|DEVICE: Light therapy intensity 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Safety, Tolerability and Immune Responses of Ebola-S and Marburg Vaccines in Healthy Adults
Status: COMPLETED
Conditions: Ebola Virus Disease|Marburg Virus Disease
Interventions: BIOLOGICAL: cAd3-Marburg|BIOLOGICAL: cAd3-EBO-S
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Inpatient Exposure Therapy and Response Prevention & Cognitive Remediation Therapy for Anorexia Nervosa
Status: COMPLETED
Conditions: Anorexia Nervosa
Interventions: BEHAVIORAL: Exposure Therapy for AN (AN-EX/RP)|BEHAVIORAL: Cognitive Remediation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PCI and Brain MRI Follow-up vs Brain MRI Follow-up Alone in Limited-stage SCLC Patients
Status: RECRUITING
Conditions: Small Cell Lung Cancer Limited Stage
Interventions: RADIATION: Prophylactic cranial irradiation|RADIATION: Thoracic radiotherapy|DRUG: Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: LOGIC-Insulin Algorithm-guided Versus Nurse-directed Blood Glucose Control During Critical Illness
Status: COMPLETED
Conditions: Critical Illness
Interventions: PROCEDURE: Nurse directed|PROCEDURE: LOGIC-Insulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Characterize the Effects of Cytochrome p450 1A2 Inhibition on Systemic Exposure to BMS-986165
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BMS-986165|DRUG: Fluvoxamine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study to Evaluate the Efficacy of an RSV F Vaccine in Older Adults
Status: COMPLETED
Conditions: Respiratory Syncytial Virus (RSV)
Interventions: BIOLOGICAL: RSV-F Vaccine|BIOLOGICAL: Phosphate Buffer Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Dose-Escalation Study Of Palbociclib + Nab-Paclitaxel In mPDAC
Status: COMPLETED
Conditions: Metastatic Pancreatic Ductal Adenocarcinoma
Interventions: DRUG: Palbociclib|DRUG: Nab-Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Topical AP611074 Gel to Treat Genital Warts
Status: COMPLETED
Conditions: Anogenital Warts|Condylomata Acuminata|Human Papillomavirus Infection
Interventions: DRUG: AP611074|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Racial Differences in the Natriuretic Peptide Response to Glucose Challenge
Status: COMPLETED
Conditions: Healthy|Natriuretic Peptides|Metabolic Syndrome
Interventions: DIETARY_SUPPLEMENT: Study diet|OTHER: Glucose Challenge
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Reinfection After Eradication of Helicobacter Pylori Infection
Status: UNKNOWN
Conditions: Bacterial Infection Due to Helicobacter Pylori (H. Pylori)|Eradication Therapy of Helicobacter Pylori|Detection of Helicobacter Pylori
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Postoperative Analgesia in Cesarean Delivery
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: PROCEDURE: Quadratus lumborum block|PROCEDURE: İlioinguinal-İliohipogastric nerve block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Depression Symptoms and Brain Activity Associated With Response to Treatment of Depression
Status: COMPLETED
Conditions: Depression
Interventions: DRUG: Venlafaxine (Effexor), Duloxetine (Cymbalta), Escitalopram (Lexapro)|OTHER: Placebo|BEHAVIORAL: Interpersonal Clinical Interaction (ICI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of MK-2060 in Healthy Participants (MK-2060-016)
Status: NOT_YET_RECRUITING
Conditions: Venous Thrombosis
Interventions: BIOLOGICAL: MK-2060|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lenalidomide in Combination With R-GemOx in First-line Treatment of Elderly Diffuse Large B Cell Lymphoma
Status: RECRUITING
Conditions: Diffuse Large B Cell Lymphoma
Interventions: DRUG: Lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Compassionate Use of Beraprost Sodium 314d Modified Release for Patients With Pulmonary Arterial Hypertension (PAH)
Status: COMPLETED
Conditions: Pulmonary Arterial Hypertension
Interventions: DRUG: BPS-314d-MR
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pre-emptive Pregabalin on Attenuating Maternal Anxiety And Stress Response To Intubation During Caesarean Section
Status: UNKNOWN
Conditions: Anxiety State|Sedation
Interventions: DRUG: Pregabalin 150mg|DRUG: multivitamin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Investigation of Omega Refractive Capsule Model V With Use of an FDA Approved IOL
Status: COMPLETED
Conditions: Cataract
Interventions: DEVICE: Omega Refractive Capsule with FDA approved Intraocular Lens|DEVICE: FDA approved Intraocular lens
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evidence Based Management of Acute Biliary Pancreatitis
Status: COMPLETED
Conditions: Acute Pancreatitis
Interventions: DIAGNOSTIC_TEST: serum lipase or amylase|DEVICE: ultrasound|DEVICE: CT|DIAGNOSTIC_TEST: Liver enzymes (Bilirubin, alanine transferase (ALT), aspartate aminotransferase, (AST) and alkaline phosphatase). Calcium. Triglycerides.|DEVICE: EUS /Secretin-stimulated magnetic resonance cholangiopancreatography (MRCP)|DRUG: Ringer lactate|COMBINATION_PRODUCT: NSAID / paracetamol +/- opiates+/- epidural analgesia|COMBINATION_PRODUCT: Quinolones + Metronidazole /Carbapenems ± Metronidazole|DIETARY_SUPPLEMENT: Fresubin 2Kcal fiber drink|DEVICE: nasogastric tube|PROCEDURE: retroperitoneal necrosectomy|PROCEDURE: open necrosectomy|PROCEDURE: Endoscopic transmural cystogastrostomy|PROCEDURE: open cystogastrostomy|PROCEDURE: percutaneous catheter drainage (PCD) for infected necrosis|PROCEDURE: Endoscopic ultrasound (EUS) guided aspiration for infected necrosis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Stearidonic Acid-Containing Foods on Eicosapentaenoic Acid Levels in Red Blood Cells and Omega-3 Index
Status: COMPLETED
Conditions: Sudden Cardiac Death|Sudden Cardiac Arrest|Cardiovascular Disease
Interventions: DIETARY_SUPPLEMENT: Sunflower Oil Softgels|DIETARY_SUPPLEMENT: EPA softgels|OTHER: Sunflower Oil Food|OTHER: SDA soybean Oil Food
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Exclusion of the Left Atrial Appendage (LAA) With the LAAx, Inc. TigerPaw System
Status: UNKNOWN
Conditions: Stroke
Interventions: DEVICE: LAAx TigerPaw System
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluation of the Efficacy and Usability of Artificial Intelligence (ChatGPT) for Health Sciences Students
Status: COMPLETED
Conditions: Educational Activities|AI (Artificial Intelligence)
Interventions: OTHER: Artificial Intelligence (ChatGPT) Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: The Effect of Acupressure on Fatigue in Individuals With Chronic Fatigue Syndrome
Status: COMPLETED
Conditions: Acupressure|Fatigue Syndrome, Chronic|Complementary Therapies|Quality of Life|Depression
Interventions: OTHER: Acupressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Investigate Changes in Airway Inflammation, Symptoms, and Rescue Therapy Utilization With AIRSUPRA Compared to Albuterol as Needed in Adults With Mild Asthma
Status: NOT_YET_RECRUITING
Conditions: Mild Asthma
Interventions: COMBINATION_PRODUCT: Albuterol/Budesonide|COMBINATION_PRODUCT: Albuterol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II Study of HMPL-004 in Patients With Ulcerative Colitis
Status: COMPLETED
Conditions: Ulcerative Colitis
Interventions: DRUG: HMPL-004 low dose|DRUG: Placebo|DRUG: HMPL-004 high dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessing the Feasibility of the Use of Visual Aids in Patient Education in Adults With Down Syndrome (DS)
Status: COMPLETED
Conditions: Down Syndrome
Interventions: BEHAVIORAL: Verbal instructions with picture diagram|BEHAVIORAL: Verbal instructions with video of ADSC|BEHAVIORAL: verbal instructions w. video of w/o DS|BEHAVIORAL: verbal instructions w. video w/DS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Exclusive Human Milk Feeding in Infants With Single Ventricle Physiology
Status: COMPLETED
Conditions: Congenital Heart Defect
Interventions: OTHER: Human Milk Derived Fortifier|OTHER: Human/Bovine Milk
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: EValuation of HumIRA® in Patients With Active Rheumatoid Arthritis, Psoriatic Arthritis and Ankylosing Spondylitis in EASTern European Countries
Status: COMPLETED
Conditions: Ankylosing Spondylitis (AS)|Psoriatic Arthritis (PsA|Rheumatoid Arthritis (RA
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Addition of Sufentanil Interscalene Block in Shoulder Surgery
Status: COMPLETED
Conditions: Postoperative Pain|Shoulder Surgery
Interventions: DRUG: Naropin 0.1% cum sufentanil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effectiveness of Intravenous Immunoglobulins (IVIG) in Toxic Shock Syndromes in Children
Status: WITHDRAWN
Conditions: Staphylococcal Infection|Streptococcal Infection
Interventions: DRUG: PRIVIGEN (CSL Behring)|DRUG: Albumin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Addressing Quality of Life, Clinical Outcomes, and Mechanisms in Uncontrolled Asthma Following the DASH Dietary Pattern
Status: RECRUITING
Conditions: Asthma
Interventions: BEHAVIORAL: Group A - Patient Education|BEHAVIORAL: Group B - Patient Education with Nutrition Counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Adherence and Compliance to ERAS in Gynecological Surgery
Status: RECRUITING
Conditions: ERAS|Gynecologic Cancer|Post Operative Pain|Ovarian Cancer|Endometrial Cancer|Cervix Cancer|Uterine Cancer|Gynecologic Neoplasm
Interventions: OTHER: Assessment of compliance to ERAS.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of RC48-ADC in Subjects With HER2-negative Locally Advanced or Metastatic Urothelial Cancer
Status: COMPLETED
Conditions: Urothelial Carcinoma
Interventions: DRUG: RC48-ADC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EFFECT OF USING SAME DERMATOME LİNE FOR ALL PORT SİTES IN LAPAROSCOPIC APPENDECTOMY IN ACUTE APANDICITIS
Status: COMPLETED
Conditions: Appendicitis
Interventions: PROCEDURE: laparoscopic appendectomy port sites
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Comparison of 000-0551 Lotion Versus Vehicle Lotion in Subjects With Plaque Psoriasis (Study -304)
Status: COMPLETED
Conditions: Plaque Psoriasis
Interventions: DRUG: 000-0551 Lotion|DRUG: Vehicle Lotion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Exploration of an Active Training Tool to Reduce Weight Bias Among Students Pursuing a Healthcare-related Degree
Status: COMPLETED
Conditions: Obesity Bias
Interventions: BEHAVIORAL: An active training tool on weight bias and knowledge about obesity|BEHAVIORAL: A short-written document on obesity
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Nigella Sativa as an Adjuvant Therapy in the Treatment of Pediatric Pneumonia
Status: RECRUITING
Conditions: Nigella Sativa Oil as an Adjuvant Therapy in the Treatment of Pneumonia
Interventions: DRUG: Nigella Sativa Oil capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Phase lb/lI Clinical Study in Advanced or Metastatic Esophageal Squamous Cell Carcinoma
Status: NOT_YET_RECRUITING
Conditions: Esophageal Squamous Cell Carcinoma
Interventions: DRUG: fruquintinib++Candonilimab+ Tegafur，Gimeracil and Oteracil Potassium
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transcranial Magnetic Stimulation (TMS) in Obsessive Compulsive Disorder (OCD): Mechanisms and Biomarkers
Status: COMPLETED
Conditions: Obsessive Compulsive Disorder
Interventions: DEVICE: Transcranial Magnetic Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Compariing a Bioactive Resin Material Used As A Fissure Sealant To A Conventional Resin
Status: UNKNOWN
Conditions: Demineralization, Tooth|Demineralization, Fissure|Non-Cavitated Caries
Interventions: OTHER: Fissure sealing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Investigation of Kidney and Urothelial Tumor Metabolism in Patients Undergoing Surgical Resection and/or Biopsy
Status: RECRUITING
Conditions: Kidney Cancer|Renal Cell Carcinoma|Clear Cell Carcinoma|Urothelial Carcinoma|Metastatic Kidney Cancer|Metastatic Urothelial Carcinoma|Papillary Renal Cell Carcinoma|Chromophobe Renal Cell Carcinoma|Fumarate Hydratase Deficiency|Succinate Dehydrogenase-Deficient Renal Cell Carcinoma|HLRCC|Hereditary Leiomyomatosis and Renal Cell Cancer
Interventions: OTHER: 13C-Glucose|OTHER: 13C-Acetate|OTHER: 13C-Lactate|OTHER: 13C-Glutamine|OTHER: 13C-Fructose
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy of Panobinostat in Patients With Relapsed and Bortezomib-refractory Multiple Myeloma
Status: COMPLETED
Conditions: Relapsed and Bortezomib Refractory Multiple Myeloma|Refractory Multiple Myeloma|Multiple Myeloma in Relapse
Interventions: DRUG: panobinostat|DRUG: bortezomib|DRUG: dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Web-based Single-session Intervention of Mindset for Improving Pre-practicum Anxiety and Coping
Status: RECRUITING
Conditions: Anxiety
Interventions: BEHAVIORAL: Web-based Single-session Intervention of Mindset on Intelligence, Failure, and Emotion (We-SMILE)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Oral Propionate to Treat and Prevent Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: DIETARY_SUPPLEMENT: Sodium propionate|DIETARY_SUPPLEMENT: Sodium Chloride|PROCEDURE: Oral glucose tolerance test|PROCEDURE: Intravenous glucose tolerance test.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Urinary Catheter 'Fill and Flush' Valve: Safety, Effectiveness, Acceptability and Feasibility Trial
Status: WITHDRAWN
Conditions: Indwelling Urinary Catheter Users
Interventions: DEVICE: Fill and Flush Valve
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Calcitriol Plus Paclitaxel in Treating Patients With Advanced Solid Tumors
Status: COMPLETED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DIETARY_SUPPLEMENT: calcitriol|DRUG: paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Effects of Core Stability Combined With Diaphragmatic Strengthening Exercises Among Asthmatic Patients
Status: COMPLETED
Conditions: Mild Intermittent Asthma
Interventions: PROCEDURE: Core stability exercise|PROCEDURE: Diaphragmatic Strengthening Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Semi-quantitative Pregnancy Test to Monitor hCG Levels After Assisted Fertility Treatment
Status: COMPLETED
Conditions: Embryo Transfer|Intrauterine Insemination (IUI)
Interventions: DEVICE: Semi-quantitative urine pregnancy test
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Prospective Assessment of Patients With Neuroendocrine Tumors and Current or Prior History of Carcinoid Syndrome or Diarrhea Undergoing Peptide Receptor Radionuclide Therapy With or Without Telotristat Ethyl
Status: WITHDRAWN
Conditions: Neuroendocrine Tumors|Carcinoid Syndrome|Diarrhea
Interventions: DRUG: Telotristat ethyl|DRUG: Peptide Receptor Radionuclide Therapy|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phase 2 Study of Human Umbilical Cord Derived Mesenchymal Stem Cell for the Treatment of Lupus Nephritis
Status: UNKNOWN
Conditions: Lupus Nephritis
Interventions: BIOLOGICAL: Human Umbilical Cord derived MSCs|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Physical and Mental Health of People With Type II Diabetes Mellitus.
Status: COMPLETED
Conditions: Adult ALL|Diabete Type 2
Interventions: OTHER: Pilates
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Nivolumab (BMS-936558) in Combination With Gemcitabine/Cisplatin, Pemetrexed/Cisplatin, Carboplatin/Paclitaxel, Bevacizumab Maintenance, Erlotinib, Ipilimumab or as Monotherapy in Subjects With Stage IIIB/IV Non-small Cell Lung Cancer (NSCLC) (CheckMate 012)
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer
Interventions: BIOLOGICAL: Nivolumab|DRUG: Gemcitabine|DRUG: Cisplatin|DRUG: Pemetrexed|DRUG: Paclitaxel|DRUG: Carboplatin|DRUG: Bevacizumab|DRUG: Erlotinib|BIOLOGICAL: Ipilimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Functional and Clinical Screening Assesment of the Shoulder Complex A New Methodological Model for Injury Management
Status: UNKNOWN
Conditions: Rotator Cuff Disease|Shoulder Impingement
Interventions: PROCEDURE: OCBRA ( Objective Criteria Based REhabilitation Algorithm
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of Mitoxantrone Hydrochloride Liposome Injection in the Treatment of Advanced Gastric Carcinoma
Status: TERMINATED
Conditions: Advanced Gastric Carcinoma
Interventions: DRUG: Mitoxantrone Hydrochloride Liposome, intravenous injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MOTIVATE to Improve Outcomes for Older Veterans With Musculoskeletal Pain and Depression
Status: RECRUITING
Conditions: Chronic Back Pain|Depression|Aging|Musculoskeletal Pain
Interventions: BEHAVIORAL: Behavioral Intervention Group (MOTIVATE)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Transcutaneous Vagus Nerve Stimulation (taVNS) Dosage Study 1
Status: RECRUITING
Conditions: Healthy
Interventions: DEVICE: transcutaneous auricular vagus nerve stimulation 30/30|DEVICE: transcutaneous auricular vagus nerve stimulation 10/10
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: International Post-Stroke Epilepsy Research Repository
Status: ENROLLING_BY_INVITATION
Conditions: Post Stroke Epilepsy|Post Stroke Seizure|Stroke|Epilepsy
Interventions: OTHER: Presence of stroke, either ischemic or hemorrhagic (intracerebral and subarachnoid)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Modulating Impulsivity in Suicidal Adolescents With Transcranial Direct Current Stimulation (tDCS)
Status: COMPLETED
Conditions: Impulsive Behavior
Interventions: DEVICE: anodal tDCS over the rIFG,|DEVICE: anodal tDCS over the lOFC,|DEVICE: sham tDCS stimulation condition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Metformin for the Treatment of Hidradenitis Suppurativa (HS)
Status: COMPLETED
Conditions: Hidradenitis Suppurativa
Interventions: COMBINATION_PRODUCT: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of the Use of Jigsaw Technique on Nursing Students' Critical Article Reviews and Students' Opinions on the Technique- Quasi-Experimental Study
Status: RECRUITING
Conditions: Education, Distance|Students, Nursing
Interventions: BEHAVIORAL: Jigsaw Technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Integrative Neuro-social Cognitive Strategy Programme for Instilling REcovery (INSPIRE) a Community-Based Cognitive Remediation Trial
Status: NOT_YET_RECRUITING
Conditions: Schizophrenia|Schizoaffective Disorder
Interventions: BEHAVIORAL: Cognitive Remediation: Adapted Neuropsychological and Education Approach to Remediation (NEAR)|BEHAVIORAL: Standard Psychiatric Rehabilitation at Anglican Care Centers
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating a Comprehensive Multimodal Outpatient Rehabilitation Program for PASC Program to Improve Functioning of Persons Suffering From Post-COVID-19 Syndrome: A Randomized Controlled Trial
Status: ENROLLING_BY_INVITATION
Conditions: Post-Acute COVID-19|Post-Acute COVID-19 Syndrome|Post-Acute COVID-19 Infection|Long COVID|Long Covid19|Dyspnea|Orthostasis|Cognitive Impairment
Interventions: OTHER: Comprehensive Rehabilitation|OTHER: Augmented Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Molecular Fluorescence Endoscopy in Patients With Familial Adenomatous Polyposis, Using Bevacizumab-IRDye800CW
Status: COMPLETED
Conditions: Adenomatous Polyposis Coli
Interventions: DRUG: Bevacizumab-IRDye800CW|DEVICE: Near infrared fluorescence endoscopy platform
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Tele-Collaborative Outreach to Rural Patients With Chronic Pain
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Pain
Interventions: BEHAVIORAL: CORPs Intervention|BEHAVIORAL: Minimally Enhanced Usual Care (MEUC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Evaluation of Efficacy and Safety of Enhanced External Counter-pulsation on Patients With Atopic Dermatitis and Inflammatory Skin Disease Requiring Wet Wrap Therapy
Status: NOT_YET_RECRUITING
Conditions: Atopic Dermatitis|Inflammatory Skin Disease
Interventions: PROCEDURE: wet wrap therapy|DEVICE: External compression counter-pulsation (EECP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radiofrequency Ablation Combined With S-1 for Pancreatic Cancer With Liver Metastasis
Status: UNKNOWN
Conditions: Carcinoma, Pancreatic
Interventions: PROCEDURE: radiofrequency ablation|DRUG: S-1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: DZD9008 in Pretreated Lung Cancer Patients With EGFR Exon20 Insertion Mutation
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: DZD9008
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the PK Profiles of LY03010 in Patients With Schizophrenia or Schizoaffective Disorder
Status: COMPLETED
Conditions: Schizophrenia|Psychotic Disorders|Mood Disorders|Schizophrenia Spectrum and Other Psychotic Disorders|Mental Disorders|Antipsychotic Agents|Tranquilizing Agents|Central Nervous System Depression|Physiological Effects of Drugs|Psychotropic Drugs|Neurotransmitter Agents|Molecular Mechanisms of Pharmacological Action
Interventions: DRUG: LY03010 156 mg treatment group, deltoid|DRUG: LY03010 156 mg treatment group, gluteal|DRUG: LY03010 351 mg treatment group, deltoid|DRUG: LY03010 351 mg treatment group, gluteal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vorinostat in Treating Patients With Stage IV Breast Cancer Receiving Hormone Therapy
Status: COMPLETED
Conditions: Male Breast Cancer|Recurrent Breast Cancer|Stage IV Breast Cancer
Interventions: DRUG: vorinostat|DRUG: anastrozole|DRUG: letrozole|DRUG: exemestane|PROCEDURE: positron emission tomography|RADIATION: F-18 16 alpha-fluoroestradiol|RADIATION: fludeoxyglucose F 18|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Iron and Prebiotics Fortification in Kenyan Infants
Status: COMPLETED
Conditions: Anemia|Iron Deficiency|Diarrhea|Malaria|Respiratory Tract Infections (RTI)|Antibiotics|Gut Inflammation|Prebiotics|Vaccine Response
Interventions: DIETARY_SUPPLEMENT: Fortified maize porridge
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect of Methylphenidate on Decision-making Ability of Attention Deficit Hyperactivity Disorder (ADHD) Adults
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: DRUG: methylphenidate|DIETARY_SUPPLEMENT: sweetener pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single Ascending Oral Doses and Effect of Food on the Bioavailability of BI 1060469
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Placebo to BI 1060469|DRUG: BI 1060469|DRUG: BI 1060469
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Short Term Effects of HMG-CoA Reductase Inhibition (Atorvastatin)on Renal Hemodynamics, Tubular Function and Vasoactive Hormones on Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: HMG-CoA reductase inhibition (atorvastatin)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose:
Clinical trial: The Effect of Doppler Ultrasound on Calcified Tendinitis
Status: NOT_YET_RECRUITING
Conditions: Calcific Tendinitis of Shoulder
Interventions: DIAGNOSTIC_TEST: ultrasound Doppler function detection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Shifting Pain Modulation From Pro-to Anti-nociceptive
Status: TERMINATED
Conditions: Post-operative Chronic Pain
Interventions: DRUG: Duloxetine|DRUG: Pregabalin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of ALS-4 in Healthy Adults Subjects
Status: COMPLETED
Conditions: Healthy Subject
Interventions: DRUG: ALS-4|DRUG: Placebo|DRUG: ALS-4|DRUG: ALS-4|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Shortwave Diathermy and Pilates Exercises in Patients With Chronic Non-specific Low Back
Status: COMPLETED
Conditions: Low Back Pain
Interventions: DEVICE: Pilates and Shortwave placebo|DEVICE: Pilates and Shortwave active
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Agonist Gonadotropin-Releasing Hormone (GnRH) Versus Antagonist GnRH
Status: UNKNOWN
Conditions: Infertility
Interventions: DRUG: ganirelix|DRUG: suprefact
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Home Based Exercises With and Without Posture and Ergonomics Training Among Students During COVID-19
Status: COMPLETED
Conditions: Musculoskeletal Pain
Interventions: OTHER: Home based exercises with postural and ergonomic training|OTHER: Home based exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Magnesium Infusion for Pain Relief After Thoracotomy. A Randomized Controlled Trial.
Status: TERMINATED
Conditions: Magnesium Sulphate|Post Pulmonary Resection|Pain
Interventions: DRUG: Placebo|DRUG: magnesium sulphate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Influence of Reducing Diets on Changes in Thyroid Parameters in Obese Women With Hashimoto's Disease
Status: COMPLETED
Conditions: Hashimoto Disease|Obesity
Interventions: BEHAVIORAL: Individually balanced elimination/reducing diets|BEHAVIORAL: Individually balanced reducing diets (without elimination)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Efficacy and Safety of Synera in Osteoarthritis Pain
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: DRUG: Synera|DRUG: Inactive patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Preventive Effect of Cow's Milk Fermented With Lactobacillus Paracasei CBA L74 on Common Infectious Diseases in Children
Status: UNKNOWN
Conditions: Upper Respiratory Tract Infections|Gastrointestinal Infection|Children, Only
Interventions: DIETARY_SUPPLEMENT: milk fermented with lactobacillus paracasei CBA L74|DIETARY_SUPPLEMENT: placebo milk formula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study Evaluating Retinal Health Monitoring System Visual Acuity Module.
Status: COMPLETED
Conditions: Age Related Macular Degeneration
Interventions: DIAGNOSTIC_TEST: Retinal Health Monitoring System Visual Acuity Module|DIAGNOSTIC_TEST: Sloan letter, logarithmic near visual acuity chart (Reference Chart)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Analysis of the Effects of Oral Colostrum Administration in Premature Infants on the Breastfeeding
Status: UNKNOWN
Conditions: Oral Colostrum Administration in Very Low Birth Weight Premature Infants
Interventions: OTHER: Oral colostrum administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Increased Enteral Protein on Body Composition of Preterm Infants
Status: ACTIVE_NOT_RECRUITING
Conditions: Premature Infant
Interventions: DIETARY_SUPPLEMENT: High protein supplementation|DIETARY_SUPPLEMENT: Standard protein supplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of TCP-ATRA for Adult Patients With AML and MDS
Status: COMPLETED
Conditions: Acute Myelogenous Leukemia|Myelodysplastic Syndromes|Leukemia
Interventions: DRUG: Tranylcypromine|DRUG: Tretinoin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cefepime vs. Ceftriaxone to Treat Nursing Home-Acquired Pneumonia
Status: COMPLETED
Conditions: Pneumonia
Interventions: DRUG: cefepime|DRUG: ceftriaxone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: S095035 in Adult Participants With Advanced or Metastatic Solid Tumors With Deletion of the Methylthioadenosine Phosphorylase (MTAP) Gene
Status: RECRUITING
Conditions: MTAP-deleted Solid Tumors
Interventions: DRUG: S095035
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ocular Surface Tolerability Study of Prostaglandin Analogues in Patients With Open-Angle Glaucoma or Ocular Hypertension
Status: COMPLETED
Conditions: Glaucoma, Open-Angle|Ocular Hypertension
Interventions: DRUG: bimatoprost ophthalmic solution 0.01%|DRUG: travoprost ophthalmic solution 0.004%|DRUG: latanoprost ophthalmic solution 0.005%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Sharing Histories: Test of a Teaching Method for Community Health Workers
Status: COMPLETED
Conditions: Infant Nutrition Disorders|Health Behavior
Interventions: BEHAVIORAL: Sharing Histories training method for CHW|BEHAVIORAL: Standard training method for CHW
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of the Cataractogenic Potential of Seroquel and Risperdal in the Treatment of Participants With Schizophrenia or Schizoaffective Disorder
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder
Interventions: DRUG: quetiapine fumarate|DRUG: risperidone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single-file Pulpectomy in Primary Molars
Status: COMPLETED
Conditions: Pulpal Necrosis
Interventions: OTHER: One Shape Single-file rotary system|OTHER: manual stainless steel K-file
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT