pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Intravenous Ketorolac Administration to Attenuate Post-procedural Pain Associated With Intrauterine Device Placement
Status: RECRUITING
Conditions: IUD|Healthy Female|Contraception|IUD Insertion Complication
Interventions: DRUG: Ketorolac|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Tacrolimus (FK506) P-III, Open-label Study in Refractory Ulcerative Colitis Patients
Status: COMPLETED
Conditions: Ulcerative Colitis
Interventions: DRUG: Tacrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety Study of Self-amplifying mRNA COVID-19 Vaccine Administered With Influenza Vaccines in Adults
Status: ACTIVE_NOT_RECRUITING
Conditions: COVID-19
Interventions: BIOLOGICAL: ARCT-2303|BIOLOGICAL: Influenza vaccine|BIOLOGICAL: Influenza vaccine, adjuvanted|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Evobrutinib in Participants With RMS
Status: TERMINATED
Conditions: Relapsing-remitting Multiple Sclerosis
Interventions: DRUG: Evobrutinib|DRUG: Avonex®|DRUG: Avonex® matched Placebo|DRUG: Evobrutinib matched Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Percutaneous Nephrolithotomy Without a Ureteral Catheter
Status: RECRUITING
Conditions: Nephrolithotomy Percutaneous|Kidney Calculi
Interventions: PROCEDURE: PCNL without reverse insertion of a ureteral catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Shared Care Approach for Seriously Ill Cancer Patients Between General Practice, Discharge Department and a Specialist Palliative Care Team
Status: WITHDRAWN
Conditions: Palliative Care|Neoplasms
Interventions: OTHER: Organisational intervention|OTHER: Referral to a specialist palliative care team.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Evaluation of ArTificial Intelligence System (Gi-Genius) for adenoMa dEtection in Lynch Syndrome.
Status: UNKNOWN
Conditions: Lynch Syndrome
Interventions: DEVICE: Gi Genius, Medtronic|OTHER: White light standart colonoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: 0.12% Chlorhexidine Oral Care for the Prevention of Non-ventilator Hospital-acquired Pneumonia
Status: COMPLETED
Conditions: Hospital-acquired Pneumonia
Interventions: DRUG: 0.12% Chlorhexidine Oral Liquid Product|DRUG: Listerine Oral Liquid Product|OTHER: Normal Saline Product
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Caring Contacts: A Strength-based, Suicide Prevention Trial in 4 Native Communities
Status: ACTIVE_NOT_RECRUITING
Conditions: Suicidal Ideation|Suicide, Attempted
Interventions: BEHAVIORAL: Caring Contacts Messages|BEHAVIORAL: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Analgesic Effect of Ultrasound Guided Maxillary Nerve Block in Trigeminal Neuralgia
Status: WITHDRAWN
Conditions: Trigeminal Neuralgia
Interventions: PROCEDURE: US guided block of maxillary nerve
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transabdominal Electrical Stimulation for Constipation
Status: COMPLETED
Conditions: Constipation
Interventions: DEVICE: Interferential Stimulation|DEVICE: TENS stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tendon-Bone Versus All-Soft-Tissue for ACL Reconstruction: A Patient-Blinded Randomized Clinical Trial
Status: RECRUITING
Conditions: Anterior Cruciate Ligament Injuries|Anterior Cruciate Ligament Rupture|Anterior Cruciate Ligament Tear
Interventions: PROCEDURE: ACL Reconstruction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: OBese Patients With Obstructive Sleep Apnea Syndrome(OSAS) and EXercise Training
Status: UNKNOWN
Conditions: Obesity|Sleep Apnea
Interventions: OTHER: Rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety of Synbiotics as Adjuvant to Influenza Vaccine in Elderly
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Synbiotic AKSB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: The Effect of the Feldenkrais Method on Pain and Function in Patients With Chronic Neck Pain
Status: ACTIVE_NOT_RECRUITING
Conditions: Neck Pain
Interventions: BEHAVIORAL: Feldenkrais Awareness Through Movement technique|BEHAVIORAL: Acupuncture|BEHAVIORAL: Stretching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluate Established Anti-DEFA5 mAbs Diagnostic Efficacy and Safety in IBD
Status: NOT_YET_RECRUITING
Conditions: Inflammatory Bowel Diseases|Ulcerative Colitis|Crohn Colitis|Indeterminate Colitis
Interventions: DIAGNOSTIC_TEST: Diagnostic Test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Single-Dose Study of MK6349 in Patients With Type 2 Diabetes (6349-002)
Status: TERMINATED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: MK6349|DRUG: Comparator: Placebo to MK6349
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Durvalumab Given With Chemoradiation Therapy in Patients With Unresectable Non-small Cell Lung Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: Durvalumab|OTHER: Placebo|DRUG: Cisplatin/ Etoposide|DRUG: Carboplatin/ Paclitaxel|DRUG: Pemetrexed/ Cisplatin|DRUG: Pemetrexed/ Carboplatin|RADIATION: Radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Implant Supported Oral Appliance Treatment of OSA
Status: TERMINATED
Conditions: Obstructive Sleep Apnea
Interventions: DEVICE: Implant Supported Mandibular Advancement Oral Appliance|DEVICE: Orthodontic Mini Implant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: More Than a Movement Disorder: Applying Palliative Care to Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson Disease|Parkinsonism|Lewy Body Disease|Supranuclear Palsy, Progressive|Parkinsonism Vascular|Multiple System Atrophy|Corticobasal Degeneration|Alzheimer Disease|Frontotemporal Dementia|Primary Progressive Aphasia|Vascular Dementia
Interventions: BEHAVIORAL: Palliative Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pre Radiotherapy Daily Exercise Training in Non-Small Cell Lung Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-Small Cell Lung Cancer Stage|Chemoradiation
Interventions: OTHER: Exercise +|OTHER: Control +
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pemetrexed-free vs. Pemetrexed-based Immunochemotherapy in Metastatic TTF-1 Negative Lung Adenocarcinoma
Status: RECRUITING
Conditions: Non-Small Cell Lung Cancer Metastatic
Interventions: DRUG: Atezolizumab|DRUG: Nab paclitaxel|DRUG: Carboplatin|DRUG: Pembrolizumab|DRUG: Cisplatin|DRUG: Carboplatin|DRUG: Pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Vasculera in Prevention on Post-op Pain and Edema Following Lower Extremity Venous Treatment in the Outpatient Setting
Status: WITHDRAWN
Conditions: Venous Insufficiency of Leg|Venous Reflux|Varicose Veins|Lower Extremity Edema Chronic
Interventions: OTHER: Vasculera|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: COACT Study: CGRPmAbs + OnabotulinumtoxinA Assessment of Chronic Migraine Treatments Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Migraine, Headache
Interventions: DRUG: Combination of Botox + CGRPmAb (Fremanezumab 225mg/1.5mL)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Local Analgesia Versus Local Peroperative Infiltration After Total Hip Replacement
Status: COMPLETED
Conditions: Total Hip Replacement
Interventions: DRUG: Locoregional anesthesia|DRUG: peroperative infiltration of local anesthetics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Electrical Neurostimulation in Cyclic Vomiting Syndrome.
Status: TERMINATED
Conditions: Cyclic Vomiting Syndrome
Interventions: DEVICE: The Bridge device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I Trial of CCT303-406 in Patients With Relapsed or Refractory HER2 Positive Solid Tumors
Status: RECRUITING
Conditions: Solid Tumor|Gastric Cancer|Breast Cancer|Ovarian Cancer|Sarcoma
Interventions: BIOLOGICAL: CCT303-406
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Posterior Quadratus Lumborum Block Using 0.125% Versus 0.25% Bupivacaine for Analgesia in Children Undergoing LPEC
Status: UNKNOWN
Conditions: Postoperative Pain
Interventions: DRUG: Bupivacaine hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Reducing Empiric VAncomycin Use in Pediatric Suspected Sepsis
Status: RECRUITING
Conditions: Sepsis|Sepsis Mrsa|Sepsis Bacteremia|Antimicrobial - Induced Nephropathy|Sepsis, Severe|Septic Shock|Septic Syndrome
Interventions: BEHAVIORAL: Multifaceted de-implementation strategy to reduce vancomycin overuse
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Clinical Trial to Evaluate the Pharmacokinetics, Safety and Tolerability of ZL-2306 (Niraparib) in Patients With Ovarian Cancer
Status: COMPLETED
Conditions: Ovarian Cancer
Interventions: DRUG: ZL-2306 (niraparib)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pragmatic Pediatric Trial of Balanced Versus Normal Saline Fluid in Sepsis
Status: RECRUITING
Conditions: Shock|Septic
Interventions: DRUG: Lactated Ringer|DRUG: Normal Saline|DRUG: Plasma-lyte
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Accuracy and Treatment Experience of Two Glucose Monitoring Systems Tested in Patients With Type 1 Diabetes and Renal Impairment
Status: COMPLETED
Conditions: Diabetes Mellitus Complication|Renal Impairment
Interventions: DEVICE: Simultanious CGM/FGM
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Local Powder Prophylactics
Status: UNKNOWN
Conditions: Infection
Interventions: BIOLOGICAL: Vancomycin|BIOLOGICAL: Vancomycin and Gentamycin|BIOLOGICAL: Cefuroxime
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety, Tolerability, and Pharmacokinetics Study of ATH-1020
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: ATH-1020|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The ELEGANT Trial: Elevate Transvaginal Mesh vs. Anterior Colporrhaphy
Status: TERMINATED
Conditions: Pelvic Organ Prolapse
Interventions: PROCEDURE: Elevate Mesh|PROCEDURE: Anterior Colporrhaphy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Olmesartan Medoxomil Versus Losartan Potassium in Patients With Mild to Moderate Essential Hypertension
Status: COMPLETED
Conditions: Essential Hypertension
Interventions: DRUG: olmesartan medoxomil|DRUG: losartan potassium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of the Quantity of Repetitive Transcranial Magnetic Stimulation(rTMS) on the Recovery After Stroke
Status: TERMINATED
Conditions: Stroke|Hemiplegia
Interventions: DEVICE: repetitive transcranial magnetic stimulation (rTMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Two Colonoscopy AI Systems for Colon Polyp Detection
Status: COMPLETED
Conditions: Adenoma|Colonoscopy|Sessile Serrated Adenoma
Interventions: DEVICE: Assist by artificial intelligence system for colon polyp detection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of Application of Transcutaneous Pulsed Electrical Stimulation Around Eye in Age-related Macular Degeneration
Status: RECRUITING
Conditions: Early to Moderate Dry Age-Related Macular Degeneration
Interventions: DRUG: Transcutaneous Pulsed Electrical Stimulation (Device: Nu Eyne M02)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GW824575 First Time in Human
Status: TERMINATED
Conditions: Retinal Diseases
Interventions: DRUG: GW824575|DRUG: GW824575 matched-placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: PEG-Intron Plus Rebetol Treatment of Chronic Hepatitis C Subjects Who Failed Response to Alpha-Interferon Plus Ribavirin (Study P02370)
Status: COMPLETED
Conditions: Hepatitis|Hepatitis C, Chronic|Fibrosis|Liver Cirrhosis
Interventions: BIOLOGICAL: PegIntron (peginterferon alfa-2b; SCH 54031)|DRUG: REBETOL (ribavirin; SCH 18908)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Daily Dose Regimens of Tiotropium 5 µg Once Daily and Tiotropium 2.5 µg Twice Daily for 4 Weeks on Top of Maintenance Therapy With Inhaled Corticosteroid Controller Medication
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Tiotropium 5 mcg qd|DRUG: Tiotropium 2.5 mcg bid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Radiosensitization With Celecoxib and Chemoradiation for Head and Neck Cancer
Status: COMPLETED
Conditions: Cancer
Interventions: DRUG: celecoxib|DRUG: Carboplatin|DRUG: Paclitaxel|RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Safety and Effectiveness of Clarithromycin Plus Zidovudine or Dideoxyinosine in the Treatment of Mycobacterium Avium Complex (MAC) Infections in Children With AIDS
Status: COMPLETED
Conditions: Mycobacterium Avium-intracellulare Infection|HIV Infections
Interventions: DRUG: Clarithromycin|DRUG: Zidovudine|DRUG: Didanosine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: A Single-ascending Dose (Part A) and Repeat-dose (Part B) Study to Investigate the Safety, Pharmacokinetics and Efficacy (Part B Only) of UCB1381 in Healthy Study Participants (Part A) and in Study Participants With Moderate to Severe Atopic Dermatitis (Part B)
Status: RECRUITING
Conditions: Atopic Dermatitis
Interventions: BIOLOGICAL: UCB1381|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Cryotherapy With Tranexamic Acid Versus Normal Saline in the Treatment of Melasma
Status: NOT_YET_RECRUITING
Conditions: Cryotherapy Effect
Interventions: DEVICE: TargetCool
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Treatment Efficacy of Combination Atypical Antipsychotics With Sertraline in Patients With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: olanzapine-sertraline combination|DRUG: only olanzapine|DRUG: risperidone-sertraline combination|DRUG: only risperidone|DRUG: paliperidone-sertraline combination|DRUG: only paliperidone|DRUG: ziprasidone-sertraline combination|DRUG: only ziprasidone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Supplementation With Conjugated Linoleic Acid (CLA) as Complementary Therapy in the Management of Type 2 Diabetes Mellitus (Women's Diabetes Study)
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: DIETARY_SUPPLEMENT: Conjugated Linoleic Acid (CLA)|DIETARY_SUPPLEMENT: Safflower OIl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lung Structure-Function In Survivors of Mild and Severe COVID-19 Infection
Status: ACTIVE_NOT_RECRUITING
Conditions: Covid19
Interventions: DIAGNOSTIC_TEST: Hyperpolarized Xenon-129 MRI of the lungs|DIAGNOSTIC_TEST: Computed Tomography (CT)|DIAGNOSTIC_TEST: Pulmonary Function Tests (PFT)|DIAGNOSTIC_TEST: Six Minute Walk Test (6MWT)|DIAGNOSTIC_TEST: Sputum analysis|DIAGNOSTIC_TEST: Blood analysis|OTHER: Questionnaires
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Mild Cognitive Impairment in Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson's Disease|Mild Cognitive Impairment
Interventions: DRUG: Exelon Patch (rivastigmine transdermal system)|DRUG: Placebo Patches
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cow's Milk and Hen's Egg Hyposensitization in Adults
Status: UNKNOWN
Conditions: Egg Allergy|Cow's Milk Allergy
Interventions: DIETARY_SUPPLEMENT: Specific Oral Tolerance Induction with Egg or Cow's milk
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Lymphatic Drainage Massage on Interdialytic Weight Gain and Fatigue
Status: RECRUITING
Conditions: Interdialytic Weight Gain|Fatigue
Interventions: OTHER: lymphatic drainage massage|OTHER: classic massage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Molar Sodium Lactate Filling in Severe Meningeal Hemorrhage
Status: RECRUITING
Conditions: Subarachnoid Hemorrhage, Aneurysmal
Interventions: DRUG: Molar Sodium Lactate|DRUG: physiological serum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Sinonasal Risk Factors for Occurrence of Unilateral Versus Bilateral Allergic Fungal Rhinosinusitis .
Status: NOT_YET_RECRUITING
Conditions: Allergic Fungal Rhinosinusitis
Interventions: DIAGNOSTIC_TEST: functional endoscopic sinus surgery
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Magnesium Sulphate, Dexemeditomedine and Emergency Agitation
Status: UNKNOWN
Conditions: Postoperative Confusion
Interventions: DRUG: Dexmedetomidine injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Cognitive Exercise Therapy Approach in Individuals With Systemic Sclerosis
Status: COMPLETED
Conditions: Systemic Sclerosis
Interventions: OTHER: Cognitive Exercise Therapy Approach (BETY)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Remimazolam Bolus for General Anesthesia
Status: COMPLETED
Conditions: Loss of Consciousness
Interventions: DRUG: 0.02 mg/kg, age<65|DRUG: 0.07 mg/kg, age<65|DRUG: 0.12 mg/kg, age<65|DRUG: 0.17 mg/kg, age<65|DRUG: 0.22 mg/kg, age<65|DRUG: 0.27 mg/kg, age<65|DRUG: 0.02 mg/kg, age≥65|DRUG: 0.07 mg/kg, age≥65|DRUG: 0.12 mg/kg, age≥65|DRUG: 0.17 mg/kg, age≥65|DRUG: 0.22 mg/kg, age≥65|DRUG: 0.27 mg/kg, age≥65
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Tranexamic Acid for Unilateral Total Knee Arthroplasty
Status: COMPLETED
Conditions: Blood Loss
Interventions: DRUG: Tranexamic Acid|DRUG: Tranexamic Acid|OTHER: haemostasia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluate the Safety and Immunogenicity of Ad5 COVID-19 Vaccines for Booster Use in Children Aged 6-17 Years.
Status: ACTIVE_NOT_RECRUITING
Conditions: COVID-19
Interventions: BIOLOGICAL: 1 Nebulized inhalation for booster groups|BIOLOGICAL: 2 Nebulized inhalation for booster groups|BIOLOGICAL: 3 Nebulized inhalation for booster groups|BIOLOGICAL: 4 Nebulized inhalation for booster groups|BIOLOGICAL: 5 Intramuscular injection for booster groups|BIOLOGICAL: 6 Intramuscular injection for booster groups|BIOLOGICAL: 7 Intramuscular injection for booster groups|BIOLOGICAL: 8 Intramuscular injection for booster groups|BIOLOGICAL: 9 Intramuscular injection for booster groups|BIOLOGICAL: 10 Intramuscular injection for booster groups|BIOLOGICAL: 11 Nebulized inhalation for booster groups|BIOLOGICAL: 12 Nebulized inhalation for booster groups|BIOLOGICAL: 13 Nebulized inhalation for booster groups|BIOLOGICAL: 14 Nebulized inhalation for booster groups|BIOLOGICAL: 15 Intramuscular injection for booster groups|BIOLOGICAL: 16 Intramuscular injection for booster groups|BIOLOGICAL: 17 Intramuscular injection for booster groups|BIOLOGICAL: 18 Intramuscular injection for booster groups|BIOLOGICAL: 19 Intramuscular injection for booster groups|BIOLOGICAL: 20 Intramuscular injection for booster groups|BIOLOGICAL: 21 Nebulized inhalation for primary groups|BIOLOGICAL: 22 Nebulized inhalation for primary groups|BIOLOGICAL: 23 Nebulized inhalation for primary groups|BIOLOGICAL: 24 Nebulized inhalation for primary groups
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety and Effectiveness of the Alma System in Treating Primary Postpartum Hemorrhage
Status: NOT_YET_RECRUITING
Conditions: Postpartum Hemorrhage \(PPH\)|Postpartum Hemorrhage \(Primary\)|PPH
Interventions: DEVICE: Alma system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: First-Line Treatment for Advanced Non-squamous Non-Small-Cell Lung Cancer With Negative Driver Gene: a Single-center, Single-Arm Trial
Status: RECRUITING
Conditions: Advanced Non-squamous Non-Small-Cell Lung Cancer
Interventions: DRUG: Sintilimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Efficacy and Side Effects Between the Obtryx and Solyx Band With 5-year Follow-up.
Status: RECRUITING
Conditions: Stress Urinary Incontinence
Interventions: DEVICE: Solyx™ SIS System|DEVICE: Obtryx™ II System (Halo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non-REm Sleep inTervention to improvE Diabetes RESTED
Status: UNKNOWN
Conditions: Type 2 Diabetes
Interventions: OTHER: Sleep Audiological Intervention Device (SleepAID)|OTHER: sham control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Value of Botox-A for Management of Low Anterior Resection Syndrome
Status: COMPLETED
Conditions: Low Anterior Resection Syndrome|Rectal Cancer
Interventions: DRUG: intra-rectal Botulinum toxin A injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RCT of the Effect of Uvulopalatopharyngoplasty Compared to Expectancy in Patients With Obstructive Sleep Apnea
Status: COMPLETED
Conditions: Obstructive Sleep Apnea Syndrome
Interventions: PROCEDURE: Uvulopalatopharyngoplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate ITCA 650 for the Treatment of Type 2 Diabetes in Patients With High Baseline HbA1c
Status: TERMINATED
Conditions: Type 2 Diabetes
Interventions: DRUG: ITCA 650 (exenatide in DUROS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study on Precutting Methods of Endoscopic Submucosal Dissection for Gastric Neoplasms Located at Lesser Curvature Side of Antrum
Status: WITHDRAWN
Conditions: Gastric Adenoma and Early Gastric Cancer
Interventions: PROCEDURE: Partial precutting|PROCEDURE: Whole precutting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Personalized Therapy for Esophagogastric Cancer Using Thymidylate Synthase Genetic Markers
Status: WITHDRAWN
Conditions: Esophagogastric Cancer
Interventions: DRUG: Pemetrexed|DRUG: Oxaliplatin|DRUG: Leucovorin|DRUG: Fluorouracil|GENETIC: Germline genotyping analyses for TSER
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multiple Dose Effects of Hydrochlorothiazide and Isosorbide Mononitrate on Glucose Homeostasis (MK-0000-117)(Completed)
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Hydrochlorothiazide (HCTZ)|DRUG: Comparator: Placebo to HCTZ|DRUG: Isosorbide mononitrate (ISMN)|DRUG: Comparator: Placebo to ISMN
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effect of Oral Paliperidone Extended-Release and Oral Risperidone Immediate-Release on Cognitive Function in Clinically Stable Patients With Schizophrenia
Status: TERMINATED
Conditions: Schizophrenia
Interventions: DRUG: Paliperidone extended-release|DRUG: Risperidone immediate-release
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficiency of Methotrexate and Tofacitinib in Mild and Moderate Patients
Status: UNKNOWN
Conditions: Takayasu Arteritis|Methotrexate|Inhibition|Treatment
Interventions: DRUG: Methotrexate Tablets|DRUG: Tofacitinib tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Osteopathic Manipulative Treatments and Neurogenic Bowel Dysfunction in Patients With Spinal Cord Injuries.
Status: COMPLETED
Conditions: Spinal Cord Injuries
Interventions: OTHER: Osteopathic Manipulative treatment (OMT)|OTHER: Manual Placebo (MP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Debulking Atherectomy Versus Stent Angioplasty for Limb Ischaemia of Diabetic Lower Limb Atherosclerosis-occlusive Disease.
Status: RECRUITING
Conditions: Peripheral Arterial Disease
Interventions: PROCEDURE: Debulking Atherectomy|PROCEDURE: Stent Angioplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cardiovascular Reserve Evaluation in Survivors of Transplant, CREST Study
Status: RECRUITING
Conditions: Acute Lymphoblastic Leukemia|Acute Myeloid Leukemia|Hematopoietic and Lymphoid Cell Neoplasm|Hodgkin Lymphoma|Myelodysplastic Syndrome|Non-Hodgkin Lymphoma|Plasma Cell Myeloma
Interventions: PROCEDURE: Bioelectric Impedance Analysis|PROCEDURE: Biospecimen Collection|PROCEDURE: Cardiopulmonary Exercise Testing|PROCEDURE: Echocardiography|PROCEDURE: Physical Performance Testing|PROCEDURE: Pulmonary Function Test|OTHER: Questionnaire Administration|PROCEDURE: Ultrasound
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study To Assess The Clinical Benefit Of Droxidopa In Subjects With Chronic Fatigue Syndrome
Status: TERMINATED
Conditions: Chronic Fatigue Syndrome|Orthostatic Hypotension|Neurally Mediated Hypotension|Neurogenic Orthostatic Hypotension
Interventions: DRUG: Droxidopa
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Social Activity, Loneliness and Stigma During COVID-19 Outbreak
Status: COMPLETED
Conditions: Covid19|Fear|Loneliness
Interventions: BEHAVIORAL: Digital social activity video intervention|BEHAVIORAL: Informational sheet|BEHAVIORAL: Stigma awareness video intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The GP's Role in Cancer Rehabilitation: a Randomised, Controlled Study.
Status: COMPLETED
Conditions: HRQOL (Health Related Quality Of Life)
Interventions: BEHAVIORAL: Two step intervention including patient interview followed by an extended information routine to the patients' GP about the patients' rehabilitation needs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Cough Assist Device in Mechanically Ventilated Patients
Status: UNKNOWN
Conditions: Mechanically Ventilated Patients
Interventions: DEVICE: Conventional tracheal suctioning|DEVICE: Mechanical insufflation/exsufflation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Drug Interaction Study Between Tegoprazan, Bismuth, Amoxicillin and Clarithromycin
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Tegoprazan|DRUG: Bismuth|DRUG: Amoxicilli|DRUG: Clarithromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Belzutifan (MK-6482) in Participants With Advanced Renal Cell Carcinoma (MK-6482-013)
Status: ACTIVE_NOT_RECRUITING
Conditions: Carcinoma, Renal Cell
Interventions: DRUG: Belzutifan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety of LEAD Radiotherapy Plus Chemoradiation in Patients With Bulky Stage III Non-Small Cell Lung Cancer
Status: TERMINATED
Conditions: Non-Small Cell Lung Cancer|NSCLC
Interventions: RADIATION: Lattice Extreme Ablative Dose (LEAD) Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of Recombinant Hepatitis B Vaccines in the Neonates
Status: UNKNOWN
Conditions: Hepatitis|Hepatitis B|Liver Diseases|Digestive System Diseases
Interventions: BIOLOGICAL: 10μg/0.5ml recombinant hepatitis B vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effectiveness of Integrating Prenatal Care in Reducing HIV/STDs Among Young Pregnant Women
Status: COMPLETED
Conditions: Pregnancy|HIV Infections|Sexually Transmitted Diseases
Interventions: BEHAVIORAL: CenteringPregnancy Plus (CP+)|BEHAVIORAL: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effect of Digital Reminiscence Therapy on People With Mild and Moderate Dementia
Status: UNKNOWN
Conditions: Dementia
Interventions: OTHER: Experimental: digital reminiscence group (DRG)|OTHER: Experimental: general reminiscence group (GRG)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Milk Types and Fish Oil in 9- to 12-Month-Old Infants
Status: COMPLETED
Conditions: Obesity|Metabolic Syndrome|Growth|Blood Pressure|Cardiovascular Disease
Interventions: BEHAVIORAL: Cow's milk with fish oil|BEHAVIORAL: Cow's milk without fish oil|BEHAVIORAL: Formula with fish oil|BEHAVIORAL: Formula without fish oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE|Primary Purpose: PREVENTION
Clinical trial: Intravitreal AAVCAGsCD59 for Advanced Dry Age-related Macular Degeneration (AMD) With Geographic Atrophy (GA)
Status: WITHDRAWN
Conditions: Dry Age-related Macular Degeneration|Geographic Atrophy|Gene Therapy|Intravitreal Injection
Interventions: BIOLOGICAL: Intravitreal AAVCAGsCD59|OTHER: Intravitreal Sham Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of the Safety and Performance of Knee Ligament Supports in the Context of a Return to Sport After Sprain
Status: UNKNOWN
Conditions: Knee Sprain (Mild)|Knee Sprain (Moderate)|Anterior Cruciate Ligament Tear
Interventions: DEVICE: kneeMID500-STRONG700
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety of Oxybutynin Versus Paroxetine in Aromatase Inhibitor-induced Vasomotor Symptoms
Status: RECRUITING
Conditions: Vasomotor Symptoms
Interventions: DRUG: oxybutynin ER|DRUG: Paroxetine CR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Personal Cancer Vaccine (NEO-PV-01) With Pembrolizumab and Chemotherapy for Patients With Lung Cancer
Status: COMPLETED
Conditions: Carcinoma, Non-Small-Cell Lung|Lung Cancer|Nonsquamous Nonsmall Cell Neoplasm of Lung
Interventions: BIOLOGICAL: NEO-PV-01|BIOLOGICAL: Pembrolizumab|OTHER: Adjuvant|DRUG: Carboplatin|DRUG: Pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination of Thrombopoietin Mimetic and Immunosuppressive Therapy in Aplastic Anaemia
Status: COMPLETED
Conditions: Aplastic Anemia
Interventions: DRUG: Combination of thrombopoietin mimetic and cyclosporin A
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Plan A Birth Control: Randomized Controlled Trial of a Mobile Health Application for Contraception Information
Status: COMPLETED
Conditions: Mobile Applications|Contraception|Contraception Behavior
Interventions: OTHER: Mobile Health Application|OTHER: Health Educator Counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Randomized Controlled Study for Analyzing Clinical Benefit of Pain Focused Sedation With Combination of Fentanyl and Propofol During Endoscopic Retrograde Cholangiopancreatography (ERCP)
Status: COMPLETED
Conditions: Endoscopic Retrograde Cholangiopancreatography
Interventions: DRUG: Conventional sedation|DRUG: Experimental sedation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: Evaluation of an Introductory Videotape Intervention to Improve Cardiac Rehabilitation Participation
Status: COMPLETED
Conditions: Myocardial Infarction|Unstable Angina|Coronary Angioplasty|Coronary Artery Bypass Surgery
Interventions: BEHAVIORAL: Survey|BEHAVIORAL: Survey and videotape
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: OTHER
Clinical trial: Effect of VLCD on the Reduction of Liver Steatosis and Fibrosis in Subjects With Obesity and NAFLD
Status: RECRUITING
Conditions: NAFLD
Interventions: DIETARY_SUPPLEMENT: Dietary intervention with very low calorie diet (VLCD)|OTHER: Control Arm
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Enriched Gardens in Nursing Home Residents With Dementia
Status: COMPLETED
Conditions: Alzheimer Disease
Interventions: OTHER: INCENTIVE VISITING A GARDEN : ENRICHED OR CONVENTIONAL SENSORY GARDEN
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Photodynamic Therapy for Papulopustular Rosacea
Status: COMPLETED
Conditions: Rosacea|Papulopustular Rosacea
Interventions: DRUG: Aminolevulinic acid topical solution 20%|DEVICE: Blu-U Light Therapy|OTHER: Placebo vehicle only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Anterior Deprogrammers for Reducing Pain and Masticatory Muscles Tension
Status: UNKNOWN
Conditions: Temporomandibular Disorders
Interventions: DEVICE: Deprogramer Sliding Guide|DEVICE: Deprogrammer Dawson B-Splint|DEVICE: Deprogrammer Kois
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Antioxydant-enriched Media on Blastocyst Euploidy Rates.
Status: RECRUITING
Conditions: Infertility|In Vitro Fertilization
Interventions: DRUG: antioxidants-enriched culture medium (Gx)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Asenapine Using an Active Control in Subjects With Schizophrenia or Schizoaffective Disorder (25520)(P05846)
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder
Interventions: DRUG: asenapine|DRUG: olanzapine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Echogenic Amniotic Fluid on Perinatal Outcome
Status: COMPLETED
Conditions: Amniotic Fluid; Disorder
Interventions: BEHAVIORAL: Significance of Echogenic Amniotic Fluid on Perinatal Outcome
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy of Pulse Electromagnetic Field Therapy (PEMF) in Patients With Subacromial Impingement Syndrome
Status: COMPLETED
Conditions: Shoulder Pain|Musculoskeletal Diseases|Subacromial Impingement Syndrome|Shoulder Injuries and Disorders
Interventions: DEVICE: Pulse electromagnetic field therapy|DEVICE: Sham pulse electromagnetic field therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Electrical Nerve Stimulation (TENS) Therapy for Pain Relief Following Total Knee Arthroplasty (TKA)
Status: COMPLETED
Conditions: Osteoarthritis, Knee|Arthritis|Pain
Interventions: DEVICE: EMPI Select TENS|DEVICE: Placebo EMPI Select TENS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: OCS Liver PROTECT Trial: Preserving and Assessing Donor Livers for Transplantation
Status: COMPLETED
Conditions: Liver Transplantation|Liver Preservation for Transplant
Interventions: DEVICE: OCS™ Liver System|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: QuitFast: Evaluating Transcranial Magnetic Stimulation as a Tool to Reduce Smoking Directly Following a Quit Attempt
Status: COMPLETED
Conditions: Smoking|Smoking Cessation|Craving|Addiction|Addiction Nicotine|Nicotine Dependence|Cigarette Smoking
Interventions: DEVICE: Real TBS to the vmPFC|DEVICE: Sham cTBS to the vmPFC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: PReoperative Very Low Energy Diets for Obese PAtients Undergoing Non-bariatric Surgery
Status: RECRUITING
Conditions: Obesity|Non-Bariatric Surgery|Preoperative Weight Loss|Preoperative Optimization
Interventions: DIETARY_SUPPLEMENT: Very Low Energy Diet with Liquid Supplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Single-stage Bilayered Skin Reconstruction With Glyaderm®
Status: COMPLETED
Conditions: Burns|Full Thickness Burn|Necrotizing Fascitis
Interventions: PROCEDURE: Dermal subsitute Glyaderm + skin graft|PROCEDURE: Skin graft alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: To Evaluate the Superiority of Fixed Combination (Orfenadrine 35mg, Acetaminophen 325mg, Caffeine 65mg and Diclofenac Sodium 50mg) Compared to Voltaren® (Diclofenac Sodium 50mg) in the Treatment of Acute Postural Low Back Pain.
Status: UNKNOWN
Conditions: Postural Low Back Pain|Mechanical Low Back Pain
Interventions: DRUG: orphenadrine, acetaminophen, caffeine and diclofenac sodium|DRUG: Diclofenac Sodium 50 MG|DRUG: Placebo (for experimental drug)|DRUG: Placebo (for Voltaren)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Low Dose Chemotherapy Versus Best Supportive Care in Progressive Pediatric Malignancies
Status: COMPLETED
Conditions: Malignant Childhood Neoplasm
Interventions: DRUG: Low dose chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Concomitant Chemo-radiotherapy in Locally Advanced Non Small Cell Lung Cancer
Status: TERMINATED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: PROCEDURE: Toxicity : Time to progression, 1 and 2 years survival
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized, Comparative Study of Hexvix Fluorescence Cystoscopy and Standard Cystoscopy in Patients With Non-invasive Bladder Cancer
Status: COMPLETED
Conditions: Bladder Cancer
Interventions: DRUG: Hexvix|OTHER: Standard white light cystoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Icotinib With Whole Brain Radiation Therapy in NSCLC Patients With Brain Metastases
Status: UNKNOWN
Conditions: Non-small-cell Lung Cancer
Interventions: DRUG: Icotinib plus WBRT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aging and the Mitochondrial Response to Exercise Training, Measured by Noninvasive 31P Magnetic Resonance Spectroscopy
Status: RECRUITING
Conditions: Physical Activity
Interventions: OTHER: Isometric Contraction Exercise - Young Adults (Age group 18-39)|OTHER: Isometric Contraction Exercise - Middle Age Adults (Age group 40-59)|OTHER: Isometric Contraction Exercise - Old Adults (Age group >60)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: HARapan kiTa ECP (External Counter Pulsation) Study HARTEC Study
Status: UNKNOWN
Conditions: Cardiac Rehabilitation|Angiogenesis|Refractory Angina
Interventions: DEVICE: External Counter Pulsation (ECP) therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT