pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Effectiveness of Positive Psychotherapy on Mental Wellbeing Among Caregivers of Cerebral Palsy Children
Status: RECRUITING
Conditions: Caregiver Burden|Mental Health Issue|Cerebral Palsy
Interventions: BEHAVIORAL: Positive Psychotherapy|BEHAVIORAL: Counseling Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combined Conventional Speech Therapy and Functional Electrical Stimulation in Dysphagia Following Stroke
Status: COMPLETED
Conditions: Dysphagia, Oropharyngeal|Stroke, Ischemic
Interventions: OTHER: Functional Electrical Stimulation|OTHER: Conventional Speech Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: [CREMA]Combination of R-M Followed by R-A in Elderly Patients With Primary CNS Lymphoma
Status: RECRUITING
Conditions: Primary CNS Lymphoma
Interventions: DRUG: Rituximab|DRUG: Methotrexate|DRUG: Cytarabine Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Weekly Paclitaxel and Trastuzumab in Metastatic Breast Cancer
Status: COMPLETED
Conditions: Metastatic Breast Cancer
Interventions: DRUG: paclitaxel plus trastuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of ProSeal Laryngeal Mask Airway to Laryngeal Mask Airway Supreme
Status: COMPLETED
Conditions: Adverse Effect of Unspecified General Anesthetics
Interventions: DEVICE: Supreme Laryngeal mask airway|DEVICE: Proseal laryngeal mask airway
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Effect of Bread Fortification With Phosphorus and Lysine on Postprandial Glycaemia and Thermogenesis
Status: UNKNOWN
Conditions: Postprandial Hyperglycemia|Energy Expenditure
Interventions: DIETARY_SUPPLEMENT: lysine and phosphorus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: VSV Versus PSV as a Weaning Mode of Mechanically Ventilated Chronic Obstructive Pulmonary Disease Patients
Status: UNKNOWN
Conditions: COPD
Interventions: PROCEDURE: pressure support ventilation mode|PROCEDURE: volume support ventilation mode
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Studies to Gain Insight How the Drugs PCSK9-inhibitors and Statins Affect Cholesterol and Bile Acid Metabolism
Status: NOT_YET_RECRUITING
Conditions: Acute Metabolic Effects of Evolocumab and Atorvastatin
Interventions: DRUG: Evolocumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Visa-versa! Breaking Instead of Pushing the Pedals-D
Status: COMPLETED
Conditions: Healthy (Controls)
Interventions: PROCEDURE: 15 minutes eccentric cycling|PROCEDURE: 15 minutes concentric (normal) cycling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Study of Forodesine in Children With Relapsed or Refractory T-cell or B-cell Precursor Acute Lymphoblastic Leukaemia or T-cell Non- Hodgkin's Lymphoma.
Status: TERMINATED
Conditions: Relapsed or Refractory T-cell Acute Lymphoblastic Leukaemia|B-cell Precursor Acute Lymphoblastic Leukaemia|T-cell Non-Hodgkin's Lymphoma
Interventions: DRUG: Forodesine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Trial of Neo-adjuvant Chemotherapy With or Without Metformin for HER2 Positive Operable Breast Cancer
Status: UNKNOWN
Conditions: HER2-positive Breast Cancer
Interventions: DRUG: Taxotere, Carboplatin, Herceptin + Pertuzumab|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Study Designed to Look at Disease Progression Using 2 Currently FDA Approved Drugs for the Treatment of RRMS
Status: TERMINATED
Conditions: Relapsing Remitting Multiple Sclerosis
Interventions: DRUG: Glatiramer Acetate|DRUG: Betaseron|DRUG: Rebif
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Nivolumab and Ipilimumab in Combination With Immunogenic Chemotherapy for Patients With Advanced NSCLC
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced NSCLC
Interventions: DRUG: Nivolumab|DRUG: Oxaliplatin|DRUG: Ipilimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of BBI608 Administrated With Sorafenib in Adult Patients With Advanced Hepatocellular Carcinoma
Status: COMPLETED
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: BBI608|DRUG: Sorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Treatment With Umbilical Cord Blood Platelet Lysate on Diabetic Foot Ulcers
Status: COMPLETED
Conditions: Diabetic Foot
Interventions: OTHER: Umbilical cord blood platelel lysate gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Video-laryngoscope With a Novel Video-stylet for Difficult Intubation
Status: COMPLETED
Conditions: Difficult Endotracheal Intubation
Interventions: DEVICE: aScope (Ambu Inc. 6740 Baymeadow Drive Glen Burnie, MD)|DEVICE: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of Saxagliptin on Glucose Fluctuation and Immune Regulation in Patients With Type 1 Diabetes
Status: UNKNOWN
Conditions: Type 1 Diabetes
Interventions: DRUG: Saxagliptin|DRUG: Insulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multimodal Pain Therapy After Hernia Repair
Status: WITHDRAWN
Conditions: Hernia, Abdominal|Pain
Interventions: DRUG: acetominophen, ibuprofen, oxycodone|DRUG: Oxycodone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of an Acceptance-based Group Behavioral Therapy for Generalized Anxiety Disorder.
Status: COMPLETED
Conditions: Generalized Anxiety Disorder
Interventions: BEHAVIORAL: Acceptance-based Behavior Therapy|BEHAVIORAL: Non-directive Supportive Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Dating Violence and HIV Prevention in Girls: Adapting Mental Health Interventions
Status: UNKNOWN
Conditions: Dating Violence|HIV Infections
Interventions: BEHAVIORAL: Cognitive-Behavioral Dating Violence and HIV Prevention Group|BEHAVIORAL: Psycho-educational Dating Violence and HIV prevention group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Use of Ultrasound in Nasogastric Tube Placement in Children Admitted to the Pediatric ICU
Status: WITHDRAWN
Conditions: Nasogastric Tube
Interventions: DIAGNOSTIC_TEST: Ultrasound following X-ray
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Randomized Study of Sulindac in Oral Premalignant Lesions
Status: COMPLETED
Conditions: Leukoplakia, Oral|Benign Neoplasms
Interventions: DRUG: sulindac|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Optic Nerve Sheath Diameter in Preeclamptic Pregnant Women Using Ultrasonography and Anesthetic Management
Status: NOT_YET_RECRUITING
Conditions: Preeclampsia|Intracranial Pressure Increase|Pregnancy; Anesthesia, Adverse Effect, Central Nervous System
Interventions: DEVICE: ultrasonography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Diabetes Medication Adherence Promotion Intervention Trial
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: BEHAVIORAL: Diabetes MAP Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Rudi Kundini, Pamoja Kundini
Status: RECRUITING
Conditions: HIV (Human Immunodeficiency Virus)
Interventions: BEHAVIORAL: PKC (adapted adherence counseling) and Conditional Cash Transfers
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Standard (180mg) Versus Double (360mg) Loading Dose of Ticagrelor in Patients With ST-elevation Myocardial Infarction (STEMI), Undergoing Primary Percutaneous Coronary Intervention (PCI)
Status: COMPLETED
Conditions: ST-elevation Myocardial Infarction
Interventions: DRUG: Ticagrelor|DRUG: Ticagrelor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combined Treatment of RFA and Sorafenib on Recurrent HCC
Status: UNKNOWN
Conditions: HCC|Radiofrequency Ablation|Sorafenib
Interventions: OTHER: RFA + Sorafenib|OTHER: RFA
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Use of Local Infiltration Analgesia Following Total Hip Arthroplasty
Status: COMPLETED
Conditions: Pain, Postoperative|Pain
Interventions: DRUG: ropivacaine and ketorolac|DRUG: Ketorolac
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Green Tea on Obese Pediatrics With Prediabetes
Status: RECRUITING
Conditions: PreDiabetes
Interventions: DRUG: Green Tea Leaf Extract Decaffeinated|DRUG: Metformin Hydrochloride 500 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparison of Subgingival Mechanotherapy With and Without the Use of a Perioscope: Clinical Trial
Status: RECRUITING
Conditions: Periodontitis
Interventions: DEVICE: subgingival mechanotherapy with perioscopy|DEVICE: classical subgingival mechanotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Radiation Therapy to the Brain or Observation in Preventing Brain Metastases in Patients With Advanced Non-Small Cell Lung Cancer
Status: UNKNOWN
Conditions: Lung Cancer
Interventions: DRUG: erlotinib hydrochloride|DRUG: gefitinib|OTHER: questionnaire administration|PROCEDURE: quality-of-life assessment|RADIATION: whole-brain radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: PREVENTION
Clinical trial: Resilience-Based Diabetes Self-Management Education (RB-DSME) for African Americans
Status: ACTIVE_NOT_RECRUITING
Conditions: Type 2 Diabetes
Interventions: BEHAVIORAL: Resilience-Based Diabetes Self-Management Education|BEHAVIORAL: Standard Diabetes Self-Management Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Dentine Hypersensitivity Treated With Laser and Fluoride.
Status: ENROLLING_BY_INVITATION
Conditions: Sensitive Dentin
Interventions: DEVICE: Laser and Fluoride|OTHER: Fluoride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Compare the Efficacy and Tolerability of the Combination of Aripiprazole and Selective Serotonin Reuptake Inhibitors (SSRIs) Used in Major Depression
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: aripiprazole , sertraline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pain Response to Cannabidiol in Induced Acute Nociceptive Pain, Allodynia and Hyperalgesia By Using a Model Mimicking Acute Pain in Healthy Adults
Status: COMPLETED
Conditions: Pain Sensation|Hyperalgesia|Allodynia
Interventions: DRUG: CBD 800 mg p.o|DRUG: Placebo p.o
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Analgesic Efficacy of External Oblique Intercostal Block vs Subcostal Transversus Abdominis Plane Block in Open Surgical Nephrectomy
Status: NOT_YET_RECRUITING
Conditions: Analgesic Efficacy|External Oblique Intercostal Block|Subcostal Transversus Abdominis Plane Block|Open|Nephrectomy
Interventions: DRUG: Transversus abdominis plane block|DRUG: External Oblique Intercostal Plane Block|DRUG: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Rubella Immunity. Response to Vaccination of Subjects With Very Low, Equivocal or Undetectable Titers of Rubella Virus Antibodies
Status: COMPLETED
Conditions: Pregnancy
Interventions: BIOLOGICAL: Determination of Anti-Rubella Antibody, E1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy of Adipose Derived Regenerative Cells (ADRCs) Delivered Via the Intracoronary Route in the Treatment of Patients With ST-elevation Acute Myocardial Infarction (AMI)
Status: COMPLETED
Conditions: Acute Myocardial Infarction
Interventions: BIOLOGICAL: Dose A|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cerebral Embolism (CE) in Catheter Ablation of Atrial Fibrillation (AF)
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: PROCEDURE: PVI with PVAC gold|PROCEDURE: PVI with Cooled-RF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess Recurrence of Actinic Keratosis in Participants Treated With Methyl Aminolevulinate Hydrochloride Cream or Vehicle Cream Who Achieved Complete Response to Treated Lesions in Earlier Study
Status: TERMINATED
Conditions: Keratosis, Actinic
Interventions: DRUG: MAL Cream|DRUG: Vehicle cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Use of Blood Biochemical Markers for Diagnostics of Heart Muscle Diseases
Status: ACTIVE_NOT_RECRUITING
Conditions: Heart Failure|Heart Dilation|Left Ventricular Hypertrophy
Interventions: DIAGNOSTIC_TEST: microRNA test|DIAGNOSTIC_TEST: Heart ultrasound examination
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Prophylactic Use of Entecavir for HBsAg Positive Lymphoma Patients Treated With Rituximab-based Immunochemotherapy
Status: UNKNOWN
Conditions: Hepatitis B
Interventions: DRUG: Entecavir prophylaxis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Brain and Renal Regional Oxygenation Using NIRS in Preterm Infants
Status: COMPLETED
Conditions: Pre-Term|Persistent Ductus Arteriosus
Interventions: DEVICE: NONIN SenSmart model X-100 near- infrared spectrometer
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Prediction of Cognitive Properties of New Drug Candidates for Neurodegenerative Diseases in Early Clinical Development
Status: COMPLETED
Conditions: Alzheimer Disease|Battery
Interventions: DRUG: Donepezil .|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Mechanical Thrombectomy for Acute Lower Limb Deep Vein Thrombosis in Tumor Patients
Status: RECRUITING
Conditions: Cancer Patients With Acute Lower Limb Deep Vein Thrombosis (DVT)
Interventions: PROCEDURE: mechanical thrombectomy (PMT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: An Open-label Study to Investigate the Clinical Efficacy of Different Dosing Regimens of Efgartigimod IV in Patients With Generalized Myasthenia Gravis
Status: ACTIVE_NOT_RECRUITING
Conditions: Generalized Myasthenia Gravis
Interventions: BIOLOGICAL: Efgartigimod concentrate for solution for infusion 20 mg/mL|BIOLOGICAL: Efgartigimod concentrate for solution for infusion 20 mg/mL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Head-to-head Comparison of [18F]F-PSMA-N5 With [18F]F-PSMA-1007 PET/CT in PCa Diagnosis, Recurrence, and Metastasis
Status: RECRUITING
Conditions: Prostate Cancer|PET/CT
Interventions: DRUG: [18F]F-PSMA-N5|DRUG: [18F]F-PSMA-1007
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Evaluate the Efficacy and Tolerance of WR279,396 for Old World Cutaneous Leishmaniasis
Status: COMPLETED
Conditions: Old World Cutaneous Leishmaniasis
Interventions: DRUG: WR279,396 with Tegaderm Dressing|DRUG: WR 279,396 with Gauze and Tape Dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I/II Study Evaluating Temferon in Multiple Myeloma Patients With Early Relapse After Front Line Therapy (TEM-MM)
Status: TERMINATED
Conditions: Multiple Myeloma
Interventions: DRUG: Temferon
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase II Clinical Trial of Reduced Port Totally Laparoscopic Distal Gastrectomy With D2 Lymph Node Dissection
Status: UNKNOWN
Conditions: Gastric Cancer
Interventions: PROCEDURE: reduced port laparoscopic distal gastrectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Determination Of Dispersion In Ultrasound Guided Quadratus Lumborum Block In Cadavers
Status: UNKNOWN
Conditions: Nerve Block
Interventions: PROCEDURE: Quadratus Lumborum Block type 2|PROCEDURE: Quadratus Lumborum Block type 3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treating Depressed Mood With a Smartphone-delivered Positive Word Stimulation for Subthreshold Depression
Status: COMPLETED
Conditions: Subthreshold Depression
Interventions: DEVICE: Smartphone Application (SPSRS)|DEVICE: Smartphone Application (YouTube)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Cohort Study of Hyperthermia and Imiquimod for the Treatment of Flat Warts
Status: UNKNOWN
Conditions: Human Papilloma Virus
Interventions: DRUG: Imiquimod treatment|DEVICE: Local Hyperthermia at 44℃
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CHIPS (Control of Hypertension in Pregnancy Study): A Pilot Trial
Status: COMPLETED
Conditions: Transient Hypertension, Pregnancy
Interventions: PROCEDURE: Randomized to either a 'less tight' group or a 'tight' group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevention of Micro-architectural Bone Decay in Males With Non-metastatic Prostate Cancer Receiving Androgen Deprivation Therapy (ADT)
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: Zoledronic acid|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Bevacizumab (Avastin) in Combination With Neoadjuvant Treatment Regimens in Participants With Primary Human Epidermal Growth Factor Receptor 2 (HER2) Negative Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Aromatase Inhibitor|DRUG: Bevacizumab|DRUG: Epirubicine|DRUG: 5-Fluorouracil (5FU)|DRUG: Cyclophosphamide|DRUG: Paclitaxel|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Single Intravenous Dose Study of E3112 in Japanese Healthy Adult Male Subjects
Status: COMPLETED
Conditions: Healthy Male Volunteers
Interventions: DRUG: Placebo|DRUG: E3112
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Mindfulness Based Cognitive Therapy for Youth With Anxiety at Risk for Bipolar Disorder
Status: COMPLETED
Conditions: Anxiety|Bipolar Disorder
Interventions: BEHAVIORAL: MBCT-C|BEHAVIORAL: Waitlist Control
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase IB Study to Evaluate the Safety of Selinexor (KPT-330) in Combination With Multiple Standard Chemotherapy or Immunotherapy Agents in Patients With Advanced Malignancies
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Malignant Solid Neoplasm|Clinical Stage III Cutaneous Melanoma AJCC v8|Clinical Stage IV Cutaneous Melanoma AJCC v8|Fallopian Tube Carcinoma|Metastatic Lung Non-Small Cell Carcinoma|Metastatic Malignant Solid Neoplasm|Metastatic Melanoma|Metastatic Renal Cell Carcinoma|Ovarian Carcinoma|Pathologic Stage III Cutaneous Melanoma AJCC v8|Pathologic Stage IIIA Cutaneous Melanoma AJCC v8|Pathologic Stage IIIB Cutaneous Melanoma AJCC v8|Pathologic Stage IIIC Cutaneous Melanoma AJCC v8|Pathologic Stage IIID Cutaneous Melanoma AJCC v8|Pathologic Stage IV Cutaneous Melanoma AJCC v8|Primary Peritoneal Carcinoma|Stage III Lung Cancer AJCC v8|Stage III Renal Cell Cancer AJCC v8|Stage IIIA Lung Cancer AJCC v8|Stage IIIB Lung Cancer AJCC v8|Stage IIIC Lung Cancer AJCC v8|Stage IV Lung Cancer AJCC v8|Stage IV Renal Cell Cancer AJCC v8|Stage IVA Lung Cancer AJCC v8|Stage IVB Lung Cancer AJCC v8|Triple-Negative Breast Carcinoma|Unresectable Lung Non-Small Cell Carcinoma|Unresectable Melanoma|Unresectable Renal Cell Carcinoma
Interventions: DRUG: Capecitabine|DRUG: Carboplatin|DRUG: Cyclophosphamide|DRUG: Doxorubicin|DRUG: Eribulin|DRUG: Fluorouracil|BIOLOGICAL: Ipilimumab|DRUG: Irinotecan Hydrochloride|DRUG: Leucovorin Calcium|BIOLOGICAL: Nivolumab|DRUG: Olaparib|DRUG: Oxaliplatin|DRUG: Paclitaxel|BIOLOGICAL: Pembrolizumab|DRUG: Pemetrexed|DRUG: Selinexor|DRUG: Topotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Augmented Reality in Learning Anatomy: The TEACHANATOMY Randomized Cross-over Trial
Status: NOT_YET_RECRUITING
Conditions: Augmented Reality|Anatomy Education
Interventions: OTHER: learning with augmented reality|OTHER: learning with traditional methods
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Efficacy of a Compassion Program in University Students
Status: ACTIVE_NOT_RECRUITING
Conditions: Mental Health Wellness
Interventions: BEHAVIORAL: Attachment-based compassion therapy|BEHAVIORAL: Relaxation program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Subjective Evaluation of Inflow Pain Associated With the Use of an Experimental Solution for Peritoneal Dialysis
Status: COMPLETED
Conditions: End Stage Renal Disease
Interventions: DRUG: Experimental Peritoneal Dialysis Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Continuous Oral Contraceptive Treatment in Premenstrual Dysphoric Disorder (PMDD)
Status: COMPLETED
Conditions: Premenstrual Dysphoric Disorder
Interventions: DRUG: Continuous OC (EE/DROS)|DRUG: Intermittent OC (EE/DROS)|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Adductor Canal Block Combined With IPACK vs Genicular Nerves Block in Knee Arthroscopy
Status: UNKNOWN
Conditions: Arthroscopy|Genicular Nerves Block
Interventions: PROCEDURE: Spinal anesthesia only|BIOLOGICAL: Spinal anesthesia and ultrasound-guided Genicular nerves block|BIOLOGICAL: Ultrasound-guided Adductor Canal block (ACB) technique with infiltration of the interspace between popliteal artery and the capsule of posterior knee block ('PACK)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ShOrt neCK AAA RAndomized Trial - ESAR and FEVAR: SOCRATES
Status: RECRUITING
Conditions: Aortic Aneurysm, Abdominal
Interventions: DEVICE: ESAR treatment: Endograft + Heli-FX Endoanchor|DEVICE: FEVAR treatment : Fenestrated endograft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Shortwave Diathermy and Therapeutic Ultrasound on Medial Tibial Stress Syndrome Among Military Cadets
Status: UNKNOWN
Conditions: Medial Tibial Stress Syndrome
Interventions: DEVICE: Therapeutic Ultrasound|DEVICE: Short wave diathermy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Radiotherapy With Hyperthermia in Recurrent and Radiation-Induced Sarcomas
Status: UNKNOWN
Conditions: Radiation Induced Neoplasms|Radiation-Induced Cancer|Recurrent Sarcoma|Recurrent Soft Tissue Sarcoma
Interventions: RADIATION: Hypofractionated radiotherapy|OTHER: Hyperthermia|RADIATION: Hypofractionated radiotherapy with boost
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chronic Cough and CANVAS (Cerebellar Ataxia With Neuropathy and Bilateral Vestibular Areflexia Syndrome)
Status: COMPLETED
Conditions: Cough|Cerebellar Ataxia|Gastroesophageal Reflux
Interventions: GENETIC: To determine the presence of biallelic expansion of AAGGG in RFC1 in patients with chronic cough, regardless of the presence of neurological symptoms.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical Evaluation of Some Local Antimicrobial Agents' Adjunctive Effects On Periodontal Parameters and Halitosis
Status: COMPLETED
Conditions: Halitosis
Interventions: DEVICE: ultrasonic (Piezon Master 700) performed with Listerine|DEVICE: ultrasonic (Piezon Master 700) performed with CHX|DEVICE: ultrasonic (Piezon Master 700) performed with serum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Blinatumomab and Nivolumab With or Without Ipilimumab in Treating Patients With Poor-Risk Relapsed or Refractory CD19+ Precursor B-Lymphoblastic Leukemia
Status: ACTIVE_NOT_RECRUITING
Conditions: Recurrent B Acute Lymphoblastic Leukemia|Recurrent Mixed Phenotype Acute Leukemia|Refractory B Acute Lymphoblastic Leukemia|Refractory Mixed Phenotype Acute Leukemia
Interventions: PROCEDURE: Biospecimen Collection|BIOLOGICAL: Blinatumomab|PROCEDURE: Bone Marrow Aspiration and Biopsy|BIOLOGICAL: Ipilimumab|BIOLOGICAL: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparative Analysis of Intertransverse Nerve Block and Paravertebral Nerve Block in Endoscopic Hepatectomy
Status: ACTIVE_NOT_RECRUITING
Conditions: Pain
Interventions: OTHER: Nerve block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of the NanoDetect-TB Mycobacterium Tuberculosis Detection Kit for the Diagnosis of Tuberculosis Disease
Status: NOT_YET_RECRUITING
Conditions: Tuberculosis, Pulmonary|Tuberculosis, Extrapulmonary|Tuberculosis Active
Interventions: DEVICE: NanoDetect-TB
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Comparison of Cognitive Function After Carotid Endarterectomy and Stenting
Status: COMPLETED
Conditions: Carotid Artery Occlusive Disease
Interventions: PROCEDURE: Carotid endarterectomy vs. carotid stenting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: How to Reduce Dry Needling Pain in Treatment of Trigger Points of Muscle Triceps Sural in Ankle Post Fracture Patients
Status: TERMINATED
Conditions: Physical Therapy Modalities|Pain Measurement|Trigger Point Pain, Myofascial|Ankle Fractures|Rehabilitation|Needles
Interventions: OTHER: Treadmill exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Analgesic Efficacy, Safety and Tolerability of Two Paracetamol-Containing Solutions in Post-Surgical Hip Replacement Pain
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: DRUG: Paracetamol (acetaminophen)|DRUG: Paracetamol 1% solution|DRUG: 0.9% sodium chloride solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Carpal Tunnel Syndrome and Static Magnetic Field Therapy
Status: UNKNOWN
Conditions: Carpal Tunnel Syndrome
Interventions: DEVICE: neodymium permanent magnet|DEVICE: neodymium magnet|DEVICE: magnet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trigger Finger Corticosteroid Injection With and Without Local Anesthetic
Status: COMPLETED
Conditions: Trigger Finger
Interventions: DRUG: Corticosteroid with lidocaine with epinephrine|DRUG: Corticosteroid with normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Improving Care for Peritoneal Dialysis Patients With the CKD-PD App
Status: COMPLETED
Conditions: Kidney Failure, Chronic|Peritoneal Dialysis Complication
Interventions: OTHER: CKD-PD app with home monitoring equipment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phase 1 Dose Escalation Study of ARQ 092 in Adult Subjects With Advanced Solid Tumors and Recurrent Malignant Lymphoma
Status: COMPLETED
Conditions: Solid Tumor|Malignant Lymphoma|Tumor
Interventions: DRUG: ARQ 092
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: NYUCI-ES: Psychosocial Intervention to Improve Health Outcomes for Chinese and Korean ADRD Caregivers
Status: RECRUITING
Conditions: Dementia Caregivers|Diabetes|Heart Disease|Overweight
Interventions: BEHAVIORAL: Treatment Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Phase I/II Study of Chondrogen Delivered by Intra-Articular Injection Following Meniscectomy
Status: COMPLETED
Conditions: Recovery Following Partial Medial Meniscectomy
Interventions: DRUG: Mesenchymal Stem Cells|DRUG: Hyaluronan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dose Escalation, MTD, Safety and PK Study of a Single Dose SC Injection of TransCon PEG Treprostinil in Healthy Male Volunteers
Status: WITHDRAWN
Conditions: PAH
Interventions: DRUG: TransCon PEG treprostinil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Short Antibiotic Treatment in High Risk Febrile Neutropenia
Status: RECRUITING
Conditions: Febrile Neutropenia
Interventions: OTHER: Early Discontinuation of Antibiotics|OTHER: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Enhancing Psychotherapy for Veterans and Service Members With PTSD and Anxiety
Status: RECRUITING
Conditions: Posttraumatic Stress Disorder|Anxiety Disorders
Interventions: BEHAVIORAL: iTCBT-I|BEHAVIORAL: iTCBT-G|BEHAVIORAL: TAU
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Estimated Oxygen Extraction Versus Dynamic Parameters for Perioperative Hemodynamic Optimization
Status: UNKNOWN
Conditions: Perioperative/Postoperative Complications|Morality
Interventions: DIAGNOSTIC_TEST: Dynamic parameters of fluid responsiveness protocol|DIAGNOSTIC_TEST: Estimated oxygen extraction protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: PRevEnting FracturEs in REnal Disease 1
Status: RECRUITING
Conditions: Kidney Diseases|Dialysis; Complications|Fragility Fracture|Chronic Kidney Disease-Mineral and Bone Disorder
Interventions: DRUG: Denosumab 60 mg/ml|OTHER: Calcium and vitamin D prophylaxis|DIAGNOSTIC_TEST: Monitoring of post-injection calcium and phosphate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: ACVBP Plus Rituximab Versus CHOP Plus Rituximab in Patients With Diffuse Large B-cell Lymphoma and Age-adjusted IPI of 1
Status: COMPLETED
Conditions: Diffuse Large-Cell Lymphoma
Interventions: DRUG: rituximab|DRUG: doxorubicin|DRUG: cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics (PK) and Safety Evaluation of Daptomycin in Children Ages 3-24 Months With Proven or Suspected Gram-positive Infections or Peri-Operative Subjects Receiving Prophylactic Antibiotics
Status: COMPLETED
Conditions: Gram Positive Bacterial Infection
Interventions: DRUG: Daptomycin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Resveratrol and First-degree Relatives of Type 2 Diabetic Patients
Status: COMPLETED
Conditions: Pre-diabetes
Interventions: DIETARY_SUPPLEMENT: placebo|DIETARY_SUPPLEMENT: resveratrol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparative Efficacy Study of 10 mg Dequalinium Chloride (Fluomizin) in the Treatment of Vulvovaginal Candidiasis
Status: COMPLETED
Conditions: Vulvovaginal Candidiasis
Interventions: DRUG: Fluomizin vaginal tablets|DRUG: Canesten vaginal tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Mobile Direct Observation Therapy (DOT) Approach in Children and Young People With Asthma
Status: COMPLETED
Conditions: Asthma in Children
Interventions: DEVICE: Mobile Direct Observation of Therapy (MDOT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Investigation of the Change of Vision-related Quality of Life in Subjects Treated With Aflibercept According to EU Label for DME.
Status: COMPLETED
Conditions: Macular Edema
Interventions: DRUG: Eylea (Aflibercept, VEGF Trap-Eye, BAY86-5321)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cognitive-Existential Group Therapy to Reduce Fear of Cancer Recurrence: A RCT Study
Status: COMPLETED
Conditions: Breast Neoplasms|Ovarian Neoplasms|Endometrial Neoplasms|Uterine Cervical Neoplasms
Interventions: BEHAVIORAL: Cognitive Existential Therapy Group 1|BEHAVIORAL: Supportive Therapy Group 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Peking University Birth Cohort in Tongzhou
Status: ACTIVE_NOT_RECRUITING
Conditions: Health Problems in Pregnancy|Pregnancy Outcomes|Gestational Diabetes|Gestational Hypertension|Preterm Birth|Obesity|Mother-Infant Interaction|Child Development|Anemia
Interventions: OTHER: No intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Reduction of Antibiotic Therapy by Biomakers in Patients With CAP Episodes (REDUCE Study)
Status: COMPLETED
Conditions: Community Acquired Pneumonia
Interventions: DRUG: Discontinuation of treatment according to CRP levels|DRUG: Discontinuation of treatment according to PCT levels|DRUG: Treatment according to current guidelines
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immediate Implant Placement Using Volume-Stable Collagen Matrix Combined With rhPDGF-BB
Status: WITHDRAWN
Conditions: Tooth Extraction|Immediate Implant Placement
Interventions: DEVICE: Xenogeneic Volume-Stable Collagen (VCMX) graft with growth factor-BB
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The MObile Health InterVEntion in Pulmonary Arterial Hypertension (MOVE PAH) Study
Status: RECRUITING
Conditions: Pulmonary Arterial Hypertension
Interventions: DEVICE: mHealth Intervention|DEVICE: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Raperazole 20mg DR Tabs and PARIET® 20 mg DR Tabs Under Fed Conditions
Status: COMPLETED
Conditions: Gastrointestinal Diseases
Interventions: DRUG: IDIAZOLE 20mg DR tabs|DRUG: PARIET 20 mg DR tabs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Effects of Acute vs. Chronic of Screen Illumination on: Sleep Efficacy and Architecture, Physiology, Emotion and Behavior: Possible Effect on Human Health
Status: COMPLETED
Conditions: Sleep|Emotion
Interventions: OTHER: No intervention- base line|OTHER: Acute|OTHER: Chronic
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of a New Communication Aid Tool to Favor Global Patient Centered Care
Status: RECRUITING
Conditions: Parkinson's Disease
Interventions: OTHER: Consulting with PARKINSUN as communication aid-tool|OTHER: Consulting without PARKINSUN as communication aid-tool
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Vinorelbine (Oral) Plus Trastuzumab for 1st-line Treatment of HER2/Neu Overexpressing Breast Cancer
Status: COMPLETED
Conditions: Carcinoma Breast Stage IV
Interventions: DRUG: Navelbine|DRUG: Herceptin|DRUG: Navelbine (oraly)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Computer Guided Placement of Zygomatic Implants in Two Different Approaches
Status: RECRUITING
Conditions: Atrophic Maxilla|Zygomatic Implants
Interventions: PROCEDURE: Zygomatic implants
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating the Safety, Tolerability, PK, and Activity of Topical ATx201 Gel in Outpatients With Impetigo
Status: COMPLETED
Conditions: Impetigo
Interventions: DRUG: ATx201|OTHER: ATx201 GEL Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Biological Efficacy Study of HerpV Vaccine With QS-21 to Treat Participants With Recurrent Genital Herpes
Status: COMPLETED
Conditions: Herpes Simplex Type 2
Interventions: DRUG: HerpV and QS-21|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Mepolizumab in Subjects With Moderate to Severe Atopic Dermatitis
Status: TERMINATED
Conditions: Dermatitis, Atopic
Interventions: DRUG: Mepolizumab 100 mg|DRUG: Placebo matching mepolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Safety and Performance Outcomes of Eyedeal IOL Implantation After Cataract Removal
Status: RECRUITING
Conditions: Lens Implantation, Intraocular
Interventions: PROCEDURE: Cataract surgery|DEVICE: Eyedeal® Model PX65AS1 IOL
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of EVP 1001-1 (SeeMore) in the Assessment of Myocardial Viability in Patients With Cardiovascular Disease
Status: COMPLETED
Conditions: ISCHEMIC CARDIOMYOPATHY
Interventions: DRUG: 'SEEMORE' - MANGANESE-ENHANCED MRI CONTRAST REAGENT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Subjective and Objective Outcome of ESS in CRSwNP
Status: RECRUITING
Conditions: CRS
Interventions: PROCEDURE: 1) Fronto-Sphenoethmoidektomie 2) Draf 2b 3) Draf 3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Encorafenib, Binimetinib and Cetuximab for Patients With BRAF V600E Mutated/pMMR Localized Colorectal Cancer
Status: RECRUITING
Conditions: Colorectal Cancer|Colon Cancer|BRAF V600E|BRAF V600 Mutation|Localized Cancer
Interventions: DRUG: Binimetinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral Hypoglycemic Therapy for Monogenic Variant Carriers of the Joslin Medalist Study
Status: ENROLLING_BY_INVITATION
Conditions: Type 1 Diabetes|Monogenic Diabetes
Interventions: DRUG: Metformin Extended Release Oral Tablet|DRUG: Sitagliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 3 Study of a H5N1 Vaccine in Adults, Elderly and Specified Risk Groups
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: H5N1 Influenza Vaccine Whole virion, Vero cell-derived, Inactivated Influenza Vaccine, non-adjuvanted|BIOLOGICAL: H5N1 Influenza Vaccine Whole virion, Vero cell-derived, Inactivated Influenza Vaccine, non-adjuvanted
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Bone Marrow Concentrate (BMC) Injection in Intervertebral Discs
Status: UNKNOWN
Conditions: Low Back Pain|Disc Disease|Disc Degeneration|Arthropathy Vertebrae|Sacral Disorder|Radiculopathy|Spinal Stenosis
Interventions: BIOLOGICAL: Bone Marrow Concentrate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Effectiveness of ABM-168 in Adults With Advanced Solid Tumors.
Status: RECRUITING
Conditions: Advanced Solid Tumor|RAS Mutation|RAF Mutation|NF1 Mutation
Interventions: DRUG: ABM-168
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vincristine Sulfate, Topotecan Hydrochloride, and Cyclophosphamide With or Without Bevacizumab in Treating Young Patients With Refractory or First Recurrent Extracranial Ewing Sarcoma
Status: COMPLETED
Conditions: Ewing Sarcoma of Bone|Extraosseous Ewing Sarcoma|Peripheral Primitive Neuroectodermal Tumor|Recurrent Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor
Interventions: DRUG: topotecan hydrochloride|DRUG: vincristine sulfate|DRUG: cyclophosphamide|BIOLOGICAL: bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT