pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Comparision Between Hemodynamic Response of Dexmedetomidine and Remifentanil on Anesthesia in Endoscopic Sinus Surgery
Status: UNKNOWN
Conditions: Hemodynamic Instability
Interventions: DRUG: Dexmedetomidine|DRUG: Remifentanil|DRUG: Epinephrine|DRUG: Propofol|DRUG: Rocuronium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy and Safety of Deoxycholic Acid Injections for Removal of Adipose Tissue in the "Bra Strap Fat" Region
Status: COMPLETED
Conditions: Brassiere Strap Fat (BSF)|Bra Strap Fat (BSF)
Interventions: DRUG: Deoxycholic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Impact of Altitude Level on Surgical Outcomes of Pancreaticoduodenectomy
Status: COMPLETED
Conditions: Periampullary Cancer
Interventions: PROCEDURE: PANCREATICODUDENECTOMY
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Axitinib for Downstaging Large Renal Tumors Not Primarily Suitable for Partial Nephrectomy (AXIPAN)
Status: COMPLETED
Conditions: cT2a N0NxM0 Renal Tumor
Interventions: DRUG: AXITINIB
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, and Pharmacokinetics of Dapsone in Acne Vulgaris
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: Dapsone Formulation A|DRUG: Dapsone Formulation B|DRUG: Dapsone Formulation C|DRUG: Dapsone 5% Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of Baricitinib (LY3009104) in Patients With Moderate to Severe Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: Baricitinib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Impact of Bed Rest, Aging and NMES on Skeletal Muscle
Status: RECRUITING
Conditions: Disuse Atrophy (Muscle) of Lower Extremities|Muscle Function|Neuromuscular Electrical Stimulation|Myofibrillar Protein Synthesis
Interventions: OTHER: Bed rest|OTHER: Neuromuscular electrical stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of Lung Administration With Three Different Nebulizer
Status: UNKNOWN
Conditions: Healthy Subjects
Interventions: DEVICE: Jet Nebulizer|DEVICE: Trunk Mask Nebulizer|DEVICE: Aerobika Nebulizer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Music on Pregnant Women With Gestational Hypertension
Status: COMPLETED
Conditions: Gestational Hypertension|Music|Blood Pressure|Anxiety|Maternal-Fetal Relations
Interventions: OTHER: music
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Autologous Myoblast Intrasphincteric Injection for Fecal Incontinence
Status: COMPLETED
Conditions: Fecal Incontinence
Interventions: OTHER: Myoblast injection|PROCEDURE: saline solution injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Total Tubeless Mini-PCNL Versus Tubeless Mini-PCNL
Status: NOT_YET_RECRUITING
Conditions: Surgery-Complications|Nephrolithiasis Staghorn Calculus|Safety Issues
Interventions: OTHER: total tubeless mini-PCNL|OTHER: tubeless mini-PCNL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: OTHER
Clinical trial: Adaptive Therapy for Post-Second-Line Advanced Breast Cancer
Status: RECRUITING
Conditions: HER2-negative Metastatic Breast Cancer
Interventions: DRUG: Gemcitabine, Vinorelbine, or Eribulin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Safety and Efficacy of IC265 Ophthalmic Solution for Dry Eye in Adult Participants
Status: RECRUITING
Conditions: Dry Eye Syndromes
Interventions: DRUG: IC265 Ophthalmic Solution 1%|DRUG: Placebo Ophthalmic Solution (Vehicle)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Aquacel Versus Iodoform Gauze for Filling Abscess Cavity Following Incision and Drainage
Status: COMPLETED
Conditions: Abscess|Cellulitis
Interventions: DEVICE: Type of dressing - Iodoform|DEVICE: Type of dressing - Aquacel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Relative Bioavailability of Different Formulations of GSK2018682, a Sphingosine-1-phosphate Receptor Subtype 1 Agonist, in Healthy Volunteers.
Status: COMPLETED
Conditions: Multiple Sclerosis, Relapsing-Remitting
Interventions: DRUG: GSK2018682 CD2 Capsule; GSK2018682 CD3 non-micronised Tablet; GSK2018682 CD3 micronised Tablet; GSK2018682 CD3 non-micronised Tablet in fed state
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Odanacatib in Postmenopausal Women Previously Treated With Alendronate (MK-0822-050)
Status: WITHDRAWN
Conditions: Osteoporosis|Postmenopausal Osteoporosis
Interventions: DRUG: Odanacatib|DRUG: Alendronate|OTHER: Placebo (odanacatib)|DIETARY_SUPPLEMENT: Cholecalciferol (Vitamin D3)|DIETARY_SUPPLEMENT: Calcium carbonate|OTHER: Placebo (alendronate)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pemetrexed Disodium and Erlotinib in Treating Patients With Advanced Non-Small Cell Lung Cancer or Other Solid Tumors
Status: COMPLETED
Conditions: Lung Cancer|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: erlotinib hydrochloride|DRUG: pemetrexed disodium
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Periodontal Treatment in Non-controlled Type 2 Diabetes Mellitus Patients. Clinical Trial
Status: COMPLETED
Conditions: Diabetes Mellitus.|Chronic Periodontitis
Interventions: PROCEDURE: conventional periodontal treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Metacognitive Therapy and Work Interventions for Patients on Sick Leave Due to Common Mental Disorders
Status: UNKNOWN
Conditions: Anxiety|Depression
Interventions: BEHAVIORAL: Metacognitive therapy and work-focused interventions|OTHER: Waiting list
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Web-administered STAIR for Patients on Behavioral Health Waitlists
Status: NOT_YET_RECRUITING
Conditions: Post Traumatic Stress Disorder
Interventions: BEHAVIORAL: webSTAIR|BEHAVIORAL: CHW coaching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Clinical Trial Evaluating the Effect of ASLAN001 in Patients With Recurrent/Metastatic Gastric Cancer Whose Tumors Are Either HER-2 Amplified or Co-expressing HER-1 and HER-2
Status: COMPLETED
Conditions: Stomach Neoplasms|Cancer of Stomach|Cancer of the Stomach|Gastric Cancer|Gastric Neoplasms
Interventions: DRUG: ASLAN001
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Misoprostol for Secondary Prevention of Postpartum Hemorrhage at the Community Level in India
Status: COMPLETED
Conditions: Postpartum Hemorrhage
Interventions: DRUG: Misoprostol|DRUG: Misoprostol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study of Icotinib Hydrochloride Cream in Patients With Mild to Moderate Psoriasis
Status: TERMINATED
Conditions: Mild to Moderate Psoriasis
Interventions: DRUG: Icotinib hydrochloride cream|DRUG: Placebo cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Soft Mist Spray Device for Airway Anaesthesia During Awake Videolaryngoscopy
Status: COMPLETED
Conditions: Airway|Anesthesia, Local
Interventions: DEVICE: Trachospray for awake videolaryngoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Fractional CO2 Laser With Topical Pentostam Treatment for Cutaneous Leishmaniasis.
Status: UNKNOWN
Conditions: Leishmaniasis
Interventions: DRUG: Local application pentostam|DRUG: intra-lisional pentostam|DEVICE: fractional CO2 laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lanreotide (Somatuline Autogel) in Thyroid-associated Ophthalmopathy Treatment
Status: TERMINATED
Conditions: Thyroid-Associated Ophthalmopathy
Interventions: DRUG: Lanreotide (Autogel formulation). Duration of treatment - 3 injections, 1 every 28 days
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Hereditary Hemorrhagic Telangiectasia (HHT) Research Outcomes Registry
Status: ACTIVE_NOT_RECRUITING
Conditions: Hereditary Hemorrhagic Telangiectasia|HHT|Arteriovenous Malformation of Brain
Interventions: OTHER: Registry and Saliva sample
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Silver Diamine Fluoride Modified Restoration In Treating Hypomineralized First Permanent Molar.
Status: COMPLETED
Conditions: Molar Incisor Hypomineralization
Interventions: OTHER: Silver Diamine Fluoride 38%|OTHER: fluoride varnish
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Medication-Assisted Treatment Implementation in Community Correctional Environments (MATICCE)
Status: COMPLETED
Conditions: Opioid-Related Disorders|Alcohol-Related Disorders
Interventions: OTHER: KPI training only|OTHER: KPI plus OLI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: A Study to Evaluate Drug-Drug Interaction of TQB3909 Tablets
Status: NOT_YET_RECRUITING
Conditions: Advanced Malignant Neoplasm
Interventions: DRUG: TQB3909 tablets|DRUG: Itraconazole capsule|DRUG: Rifampicin capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Maplirpacept (PF-07901801),Tafasitamab, and Lenalidomide in People With Relapsed or Refractory Diffuse Large B-cell Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Diffuse Large B-Cell Lymphoma
Interventions: DRUG: Maplirpacept|DRUG: Tafasitamab|DRUG: Lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Two Different Distention Medium in Diagnostic Hysteroscopy
Status: COMPLETED
Conditions: Hysteroscopy, Distension Medium, Pain
Interventions: PROCEDURE: diagnostic hysteroscopy|DRUG: physiological solution|DRUG: carbon dioxide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: COVID-19 Supplemental Vaccine Boost to Enhance T Cell Protection in Those Who Have Already Received EUA S-Based Vaccines
Status: WITHDRAWN
Conditions: Covid19
Interventions: BIOLOGICAL: hAd5-S-Fusion+N-ETSD vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety of Testosterone Undecanoate i.m. in Hypogonadal Men
Status: COMPLETED
Conditions: Hypogonadism
Interventions: DRUG: Testosterone Substitution by Testosterone Undecanoate i.m.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical and Microbiological Comparison of 0.2% CHX and 0.05% CHX+0.05%CPC Mouthwashes in TPS Patients
Status: RECRUITING
Conditions: Chlorhexidine|Gingivitis|Periodontitis|Cetylpyridinium Chloride
Interventions: DEVICE: Mouthwash containing 0.12% CHX (Chlorhexidine)|DEVICE: Mouthwash containing 0.05% CHX (Chlorhexidine) and 0.05% CPC (Cetylpyridinium Chloride)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Hemodynamic Effects of Delayed Umbilical Cord Clamping in Full-term Newborns
Status: COMPLETED
Conditions: Cardiac Output, High|Cardiac Output, Low
Interventions: PROCEDURE: Delayed cord clamping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Prolonged Intravenous Therapy Versus Early Initiation of an Oral Loop Diuretic in Decompensated Heart Failure
Status: RECRUITING
Conditions: Heart Failure
Interventions: DRUG: Furosemide Pill 150% equivalent iv dose|DRUG: Furosemide Pill 200% equivalent iv dose|DRUG: Furosemide Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Medroxyprogesterone +/- Cyclophosphamide & Methotrexate in Hormone Receptor-Negative Recurrent/Metastatic Breast Cancer
Status: COMPLETED
Conditions: Estrogen Receptor-negative Breast Cancer|Progesterone Receptor-negative Breast Cancer|Recurrent Breast Cancer|Stage IV Breast Cancer
Interventions: DRUG: Medroxyprogesterone progesterone acetate (MPA)|DRUG: Medroxyprogesterone with Cyclophosphamide + Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Vaginal and Sublingual Misoprostol 50 µg for Cervical Ripening Prior to Induction of Labor
Status: COMPLETED
Conditions: Cervical Ripening
Interventions: DRUG: Sublingual misoprostol|DRUG: Vaginal misoprostol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Olodaterol Bridging Study in Asthma
Status: WITHDRAWN
Conditions: Asthma
Interventions: DEVICE: Respimat|DEVICE: Respimat|DEVICE: Respimat|DEVICE: Respimat|DEVICE: Respimat|DEVICE: Respimat|DEVICE: Respimat|DRUG: Olodaterol|DRUG: Olodaterol|DRUG: Olodaterol|DRUG: Olodaterol|DRUG: Olodaterol|DRUG: Olodaterol|DRUG: Olodaterol|DRUG: Olodaterol & BI54903|DRUG: Olodaterol & BI54903|DRUG: Olodaterol & BI54903|DRUG: Olodaterol & BI54903|DRUG: Olodaterol & BI54903|DRUG: Olodaterol & BI54903|DRUG: Olodaterol & BI54903|DRUG: BI54903|DRUG: BI54903|DRUG: BI54903|DRUG: BI54903|DRUG: BI54903|DRUG: BI54903|DRUG: BI54903
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: AMP30: Autologous Fat Grafting, Amputation Sites Pain: Randomized
Status: COMPLETED
Conditions: Wounded Warrior|Limb Shortening|Amputation
Interventions: DEVICE: Enhanced Fat Grafting|PROCEDURE: Standard fat graft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Evaluate the Effect of Advagraf Conversion From Prograf in Liver Transplant Subjects
Status: COMPLETED
Conditions: de Novo Liver Transplant Subjects
Interventions: DRUG: Prograf|DRUG: Advagraf
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Life Coaching With Diabetes on Glycemic Control, Strengthening Diabetes and Self-management
Status: COMPLETED
Conditions: Diabetes Mellitus|Nurse-Patient Relations|Nurse's Role
Interventions: BEHAVIORAL: life coaching group with diabetes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Magnetic Prefrontal Stimulation for Studying the Role of the Cortex in High-level Cognition Processes and Reward System
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DEVICE: TMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Self Regulated Physical Activity and Bone Growth Enhancement in Premature Infants
Status: COMPLETED
Conditions: Prematurity|VLBW - Very Low Birth Weight Infant
Interventions: OTHER: Prepod|PROCEDURE: Joint compression exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: LIFEMEL Efficacy in Preventing Haematopoietic Toxicity in Patients Treated With Chemotherapy
Status: COMPLETED
Conditions: Neutropenia|Adverse Event
Interventions: DIETARY_SUPPLEMENT: Lifemel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study to Determine the Efficacy of Bendamustin in Patients With Recurrent Small Cell Lung Cancer (SCLC)
Status: UNKNOWN
Conditions: Recurrent Small Cell Lung Cancer
Interventions: DRUG: Bendamustin/Ribomustin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Autologous Conditioned Plasma Treatment for Conservative Treated Total Achilles Tendon Tears
Status: COMPLETED
Conditions: Tendon Rupture
Interventions: OTHER: Saline|OTHER: ACP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acceptability, Feasibility, Safety and Efficacy of a Optimized Rehabilitation Program for Treated Patients With Spinal Muscular Atrophy (SMA).
Status: RECRUITING
Conditions: Spinal Muscular Atrophy
Interventions: OTHER: Optimized rehabilitation program
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Efficacy and Safety Study of BF2.649 in the Treatment of Excessive Daytime Sleepiness in Narcolepsy
Status: COMPLETED
Conditions: Narcolepsy|Excessive Daytime Sleepiness|Cataplexy|Sleep Disorders
Interventions: DRUG: BF2.649|DRUG: Modafinil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Rollover Study for Patients With Sickle Cell Disease Who Have Completed a Prior Novartis-Sponsored Crizanlizumab Study
Status: RECRUITING
Conditions: Sickle Cell Disease
Interventions: DRUG: Crizanlizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Benazepril Hydrochloride, Lisinopril, Ramipril, or Losartan Potassium in Treating Hypertension in Patients With Solid Tumors
Status: TERMINATED
Conditions: Hypertension|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: lisinopril|DRUG: losartan potassium|OTHER: laboratory biomarker analysis|DRUG: benazepril hydrochloride|DRUG: ramipril
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Subcutaneous Wound Infiltration of Ketamine or Bupivacaine Pain Perception After Cesarean Section
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: Ketamine|DRUG: Bupivacaine|DRUG: Placebo (0.9% saline solution)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Hemopatch to Prevent Lymphatic Leak After Robotic Prostatectomy and Pelvic Lymph Node Dissection
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DEVICE: Hemopatch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Nursing Students' Performance During Guided Debriefing With the Lasater Clinical Judgement Rubric
Status: COMPLETED
Conditions: Educational Activities
Interventions: OTHER: Debriefing with TeamGAINS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Angiotensin-converting-enzyme (ACE) Inhibitors in Hemodialysis
Status: COMPLETED
Conditions: Left Ventricular Hypertrophy|Hypertension
Interventions: DRUG: ACE inhibitor Ramipril|DRUG: non-RAS inhibitor antihypertensive therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Metformin and Sitagliptin in Women With Previous Gestational Diabetes
Status: COMPLETED
Conditions: Pre-diabetes
Interventions: DRUG: Metformin|DRUG: Sitagliptin|DRUG: Sitagliptin + Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics of Immediate-Release vs. Delayed-Release Omeprazole in Gastroparesis
Status: COMPLETED
Conditions: Gastroparesis|Gastroesophageal Reflux Disease
Interventions: DRUG: Immediate-release omeprazole|DRUG: Delayed-release omeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mostafa Maged Maneuveur to Prevent and Control Post-partum Haemorrhage During Normal Vaginal Delivery
Status: COMPLETED
Conditions: Post Partum Hemorrhage
Interventions: PROCEDURE: Mostafa Maged maneuver
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate YH001 in Combination With Toripalimab in Subjects With Advanced NSCLC and HCC
Status: WITHDRAWN
Conditions: HCC|NSCLC Stage IIIB|NSCLC Stage IV
Interventions: DRUG: YH001 + Toripalimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Novel Method for Chronic Anal Fissure Treatment
Status: COMPLETED
Conditions: Anal Fissure
Interventions: OTHER: ADRCs therapy|DEVICE: Celution|DEVICE: Tulip cannulas|OTHER: 20mL Lidocaine 2% and Epinephrine 1:100 000
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Detection of Aspergillus Fumigatus and Sensitization in COPD Patients With Bronchiectasis vs Without Bronchiectasis
Status: UNKNOWN
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: PROCEDURE: Sputum induction|PROCEDURE: Skin prick test|OTHER: Questionnaires
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Safety and Tolerability Study of Denufosol in 2-4 Year Olds
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: denufosol tetrasodium Inhalation Solution|DRUG: 0.9% w/v sodium chloride solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Appalachians Together Restoring the Eating Environment: Improving Healthy Diet in Rural Appalachian Kentucky
Status: COMPLETED
Conditions: Feeding Behavior|Drinking Behavior
Interventions: BEHAVIORAL: School-based water campaign|BEHAVIORAL: Community cooking classes
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluating Long Acting Beta Agonists Used to Treat Asthma Among Those With Either Arg/Arg or Gly/Gly Genotypes
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Fluticasone with salmeterol|DRUG: Fluticasone HFA|DRUG: Ipratropium HFA|DRUG: Albuterol HFA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rehabilitation After Coronary Bypass Grafting. Comparison of Different Types of Rehabilitation Programs
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: BEHAVIORAL: Rehabilitation in institution|BEHAVIORAL: Rehabilitation at home|BEHAVIORAL: Out-patient rehabilitation at the hospital
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic (PK) Study of the 200 Microgram (mcg) Misoprostol Vaginal Insert (MVI 200) in Women at Term Gestation (The MVI-PK Study)
Status: COMPLETED
Conditions: Cervical Ripening|Induction of Labor
Interventions: DRUG: MVI 200
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Cabozantinib Plus Durvalumab With or Without Tremelimumab in Patients With Gastroesophageal Cancer and Other Gastrointestinal Malignancies
Status: ACTIVE_NOT_RECRUITING
Conditions: Gastric Cancer|Esophageal Adenocarcinoma|Hepatocellular Carcinoma|Colorectal Cancer
Interventions: DRUG: Cabozantinib|DRUG: Durvalumab|DRUG: Tremelimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A DDI Study of FDL169 and FDL176 in Healthy Subjects
Status: SUSPENDED
Conditions: Cystic Fibrosis
Interventions: DRUG: FDL169|DRUG: FDL176
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Determine the Efficacy, Safety and Pharmacokinetics of GMI-1271 as Adjunct to Standard of Care for the Treatment of Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: GMI-1271
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Effectiveness of NXY-059 for the Treatment of Patients Who Have Suffered From a Stroke
Status: COMPLETED
Conditions: Cerebral Stroke|Stroke, Acute|Cerebrovascular Stroke|Ischemic Attack, Transient
Interventions: DRUG: NXY-059
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: High Dose Donor Hematopoietic Stem Cell Infusion for Relapsed/Refractory AML
Status: UNKNOWN
Conditions: Leukemia, Myeloid
Interventions: BIOLOGICAL: hematopoietic stem cell
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Total Neoadjuvant Chemoradiotherapy Plus Anti-PD-1 in Subperitoneal Patients With Locally Advanced Rectal CancerPatients With Locally Advanced Rectal Cancer: A Prospective, Single Arm, Exploratory Study
Status: NOT_YET_RECRUITING
Conditions: Locally Advanced Rectal Cancer|Total Neoadjuvant Treatment|Anti-PD-1
Interventions: OTHER: nCRT → (CapeOX+Sintilimab)×6 → Surgery/W&W
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Detection of Circulating Tumor Cells (CTCs) in Patients With Colorectal Cancer Undergoing Cryosurgery Combined With DC-CIK Treatment
Status: COMPLETED
Conditions: Neoplastic Cells, Circulating
Interventions: OTHER: Flow cytometry (FCM)|OTHER: RT-PCR
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Identification of Criteria of the Success of the Endarterectomy in Chronic Pulmonary Post Embolic Hypertension
Status: COMPLETED
Conditions: Chronic Thromboembolic Pulmonary Hypertension
Interventions: OTHER: Angiography and Computed Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Hydrocortisone Replacement in Patients With Secondary Adrenal Insufficiency (SUPREME CORT)
Status: COMPLETED
Conditions: Adrenal Insufficiency
Interventions: DRUG: Hydrocortisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Atrial Fibrillation Management in Congestive Heart Failure With Ablation
Status: COMPLETED
Conditions: Persistent Atrial Fibrillation|Heart Failure|ICD
Interventions: DEVICE: ICD/CRT implant|PROCEDURE: AF ablation|OTHER: Best Medical Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CPPopt Guided Therapy: Assessment of Target Effectiveness
Status: COMPLETED
Conditions: Brain Injuries, Traumatic|Cerebrovascular Circulation|Homeostasis
Interventions: OTHER: For both groups, CPP targets will be achieved first by ICP control if this is raised and then by ABP support by titration (up or down) of vasopressors and fluids according to local protocols.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Low-dose Spiral Breast CT With MRI in Major Indications of MRI for Breast Diagnostics
Status: RECRUITING
Conditions: Breast Cancer Diagnosis
Interventions: DIAGNOSTIC_TEST: Injection of contrast enhancing agent Gadovist for MRI investigation|DIAGNOSTIC_TEST: Injection of contrast enhancing agent Imeron for B-CT investigation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Atlas of Retinal Imaging in Alzheimer's Study
Status: RECRUITING
Conditions: Alzheimer Disease|Mild Cognitive Impairment|Mild Dementia|Aging|Cognitive Change
Interventions: OTHER: Retinal Imaging|OTHER: Pupillometry|OTHER: Contrast Sensitivity|DIAGNOSTIC_TEST: Neuropsychological Evaluation|GENETIC: APOE genotyping|OTHER: blood draw|OTHER: Gait Assessment|OTHER: Actigraphy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of Tirzepatide (LY3298176) in Chinese Participants With Type 2 Diabetes (SURPASS-CN-MONO)
Status: ACTIVE_NOT_RECRUITING
Conditions: Type 2 Diabetes
Interventions: DRUG: Tirzepatide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of the NO-donor Pentaerythrithyltetrantrate on Perinatal Outcome in High-risk Pregnancies
Status: COMPLETED
Conditions: High Risk Pregnancy
Interventions: DRUG: PETN|DRUG: Placebo control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Nab-paclitaxel Plus Gemcitabine in Chinese Patients With Advanced Pancreatic Cancer
Status: UNKNOWN
Conditions: Advanced Pancreatic Cancer
Interventions: DRUG: nanoparticle albumin-bound paclitaxel|DRUG: gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vitamin Deficiency and Blood Pressure in Hospitalized Jewish General Hospital (JGH) Patients
Status: COMPLETED
Conditions: Vitamin C Deficiency|Vitamin D Deficiency
Interventions: DIETARY_SUPPLEMENT: Vitamin D|DIETARY_SUPPLEMENT: Vitamin C
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Shoulder Stretches
Status: COMPLETED
Conditions: Shoulder Impingement|Shoulder Pain|Adhesive Capsulitis|Rotator Cuff Tears|Posterior Capsule Tear|Glenohumeral Subluxation|Glenohumeral Dysplasia|Acromioclavicular; Sprain (Strain)|Internal Rotation Contracture-shoulder|External Rotation Contracture-Shoulder|Flexion Contracture|Extension Contracture-Shoulder
Interventions: OTHER: pragmatic posterior capsular stretch|OTHER: cross body stretch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effects of Acupuncture Press Needle in Mild to Moderate Obstructive Sleep Apnea Patients
Status: UNKNOWN
Conditions: Apnea, Obstructive Sleep|Snoring
Interventions: DEVICE: acupuncture press needle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Vitamin K2 and D3 Intervention Trial in Children and Adolescents With the Low-energy Fractures
Status: UNKNOWN
Conditions: Fracture Healing|Vitamin D3|Deficiency of Vitamin K2
Interventions: DIETARY_SUPPLEMENT: Vitamin D and K2 supplementation|DIETARY_SUPPLEMENT: Vitamin D supplementation|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Examining the Effect of Exercise in People With Rheumatoid Arthritis Taking Anti-TNFalpha Medication
Status: UNKNOWN
Conditions: Arthritis, Rheumatoid
Interventions: OTHER: Gym exercise group intervention|OTHER: Hydrotherapy group exercise intervention|OTHER: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of Meptin® Swinghaler® and Ventolin® MDI in Stable Asthma Patients
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Meptin® Swinghaler|DRUG: Ventolin® MDI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pain and Quality of Life After Retromuscular Ventral Hernia Repair (RECOVER)
Status: RECRUITING
Conditions: Ventral Hernia
Interventions: PROCEDURE: Open retromuscular ventral hernia repair|PROCEDURE: Laparoscopic retromuscular ventral hernia repair|DEVICE: Robotic-assisted retromuscular ventral hernia repair
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Oral Motor Facilitation Technique And Traditional Exercises on Children With Cerebral Palsy
Status: RECRUITING
Conditions: Cerebral Palsy (CP)
Interventions: BEHAVIORAL: oral motor facilitation technique group|OTHER: traditional oral motor exercises group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Toripalimab and Gemcitabine in Recurrent or Metastatic Nasopharyngeal Carcinoma.
Status: ACTIVE_NOT_RECRUITING
Conditions: Nasopharyngeal Carcinoma|Recurrent Nasopharyngeal Carcinoma|Metastatic Nasopharyngeal Carcinoma|Chemotherapy Effect|Immunotherapy
Interventions: DRUG: Toripalimab plus gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Compare Two Skin Substitute Categories for Their Effectiveness to Treat Diabetic Foot Ulcers
Status: RECRUITING
Conditions: Diabetic Foot Ulcer
Interventions: DEVICE: SOC and Advanced Bioengineered Skin Substitute|OTHER: SOC and Active Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Curcumin/Turmeric as a Treatment for Patients With Subdural Hematomas Recurrence
Status: WITHDRAWN
Conditions: Hematoma, Subdural, Chronic
Interventions: DRUG: Curcumin Pill|DRUG: Placebo pills
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Ondansetron on Hemodynamics in Cesarean Section Under Spinal Anesthesia
Status: COMPLETED
Conditions: Ondansetron|Cesarean Section|Spinal Anesthesia|Hemodynamics
Interventions: DRUG: Ondansetron 8Mg/4mL Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Phase I-II Study of PAXG in Stage III-IV Pancreatic Adenocarcinoma
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DRUG: cisplatin|DRUG: capecitabine|DRUG: gemcitabine|DRUG: nab-paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Evobrutinib in Participants With RMS (evolutionRMS 1)
Status: TERMINATED
Conditions: Relapsing Multiple Sclerosis
Interventions: DRUG: Evobrutinib|DRUG: Placebo (match to Teriflunomide)|DRUG: Teriflunomide|DRUG: Placebo (match to Evobrutinib)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: To Evaluate the Safety, Tolerability, and Pharmacokinetics Profiles of TG-1000 in Healthy Volunteers, and the Food Effect on Pharmacokinetics of Single Oral Dose of TG-1000 in Healthy Volunteers.
Status: COMPLETED
Conditions: Healthy Chinese Volunteers
Interventions: DRUG: TG-1000|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Platelet Transfusion and Repeat TEG-PM in Patients With Severe TBI on Antiplatelet Therapy (Repeat TEG-PM)
Status: ENROLLING_BY_INVITATION
Conditions: Traumatic Intracranial Hemorrhage
Interventions: DIAGNOSTIC_TEST: Repeat Thromboelastography with Platelet Mapping
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of the Effectiveness and Safety of the Ulthera® DeepSEE® System for Treating Skin Laxity in the Lower Face and Submentum
Status: COMPLETED
Conditions: Improvement in Skin Laxity of the Lower Face and Submentum
Interventions: DEVICE: Ultherapy treatment|DEVICE: Untreated-control / delayed-treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Non-antithrombotic Therapy After Transcatheter Aortic Valve Implantation Trial
Status: RECRUITING
Conditions: Aortic Stenosis|TAVI(Transcatheter Aortic Valve Implantation)|Aspirin|DAPT(Dual Antiplatelet Therapy)|SAPT(Single Antiplatelet Therapy)
Interventions: DRUG: Aspirin group|DRUG: Non-antithrombotic group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: NAVA Unloading - Effects on Distribution of Ventilation
Status: UNKNOWN
Conditions: Acute Respiratory Failure
Interventions: DEVICE: Neurally adjusted ventilatory assist|DEVICE: PScli1|DEVICE: PScli2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Quantitative Electroencephalogram and Bispectral Index Brain Mapping During Propofol vs Sevoflurane General Anesthesia
Status: COMPLETED
Conditions: Neurophysiology
Interventions: DRUG: Propofol 1 % Injectable Suspension|DRUG: Sevoflurane inhalant product
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pilot Study on the Effects of Intravenous Ketamine on Acute Pain Crisis in Patients With Sickle Cell Disease
Status: TERMINATED
Conditions: Sickle Cell Disease
Interventions: DRUG: Ketamine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assess the Safety and Immunogenicity of NDV-HXP-S Vaccine in Thailand
Status: COMPLETED
Conditions: Covid-19|SARS Pneumonia|Pneumonia, Viral|Covid-19 Vaccine
Interventions: BIOLOGICAL: Normal Saline|BIOLOGICAL: NDV-HXP-S vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy Study of Vemurafenib and High-dose Interferon Alfa-2b in Melanoma
Status: COMPLETED
Conditions: Melanoma
Interventions: DRUG: High-dose Interferon alfa-2b|DRUG: Vemurafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Autologous Tumor-infiltrating Lymphocytes Therapy in Patients With Hepatocellular Carcinoma
Status: RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: PROCEDURE: Autologous Tumor-infiltrating Lymphocytes
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study in Patients With Metastatic Prostate Cancer to Assess How the Drug Eligard®, Affects Certain Markers in Blood and Urine, Which Are Indicators for the Disease
Status: TERMINATED
Conditions: Metastatic Prostate Cancer
Interventions: DRUG: Eligard
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: HER2 Expression Detection and Radionuclide Therapy in Breast Cancer Using 99mTc/188Re Labeled Single Domain Antibody
Status: RECRUITING
Conditions: Breast Cancer|Radiotoxicity
Interventions: DRUG: Injection of 99mTc-NM-02|DRUG: Injection of 188Re-NM-02
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Analysis of Neuromuscular Responses and the Balance After the Application of Physiotherapy Resources
Status: COMPLETED
Conditions: Musculoskeletal Injuries|Cryotherapy Effect|Complication of Diathermy Procedure
Interventions: OTHER: Physiotherapy resources
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Tolerability and Efficacy of UV1 Vaccine in Patients With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma Planned for First-line Treatment With Pembrolizumab
Status: RECRUITING
Conditions: Head and Neck Squamous Cell Carcinoma
Interventions: BIOLOGICAL: UV1|DRUG: Sargramostim for Injection|DRUG: Pembrolizumab injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Routinely Measured Patient-reported Outcomes in Hemodialysis Care
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Kidney Disease Requiring Chronic Dialysis
Interventions: OTHER: PROMs Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Meta-analyses of the Effect of 'Catalytic' Doses of Fructose and Its Epimers on Carbohydrate Metabolism
Status: UNKNOWN
Conditions: Overweight|Obesity|Dysglycemia|Prediabetes|Metabolic Syndrome|Type 2 Diabetes
Interventions: OTHER: fructose, allulose, tagatose, or sorbose
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: EUS-guided Choledochoduodenostomy for Primary Drainage of Malignant Distal Biliary Obstruction
Status: RECRUITING
Conditions: Biliary Obstruction|Pancreas Neoplasm|Distal Cholangiocarcinoma
Interventions: DEVICE: EUS-CDS
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Therapeutic Effect of Transcranial Direct Current Stimulation on Depression in Parkinson's Disease
Status: TERMINATED
Conditions: Parkinson Disease|Depression
Interventions: DEVICE: active tDCS|DRUG: Sertraline|DEVICE: sham tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Developing a Test for the Detection of Ovarian Cancer
Status: RECRUITING
Conditions: Ovarian Neoplasms|Ovarian Epithelial Carcinoma|Fallopian Tube Neoplasms|High Grade Ovarian Serous Adenocarcinoma|Stage I Ovarian Cancer|Stage II Ovarian Cancer|Stage III Ovarian Cancer AJCC v8|Stage IIIA Ovarian Cancer AJCC v8|Stage IIIA1 Ovarian Cancer AJCC v8|Stage IIIA2 Ovarian Cancer AJCC v8|Stage IIIB Ovarian Cancer AJCC v8|Stage IIIC Ovarian Cancer AJCC v8|Stage IV Ovarian Cancer AJCC v8|Stage IVA Ovarian Cancer AJCC v8|Stage IVB Ovarian Cancer AJCC v8
Interventions: DIAGNOSTIC_TEST: Uterine lavage, or a wash of the womb|DIAGNOSTIC_TEST: Blood sample|DIAGNOSTIC_TEST: Pap smear
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Evaluate the Efficacy and Safety of CYH33 in Patients With Recurrent/Persistent Ovary Clear Cell Carcinoma
Status: UNKNOWN
Conditions: Ovarian Cancer|Recurrent Cancer
Interventions: DRUG: CYH33
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cervical Orthosis Versus no Orthosis Following Multi-level Posterior Cervical Fusion
Status: COMPLETED
Conditions: Posterior Cervical Spinal Surgery|Myelopathy Cervical|Radiculopathy, Cervical|Spinal Stenosis Cervical|Spondylosis, Cervical
Interventions: DEVICE: Cervical Orthosis (CO)|DEVICE: No Orthosis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT