pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: The Clinical Utility of Extracorporeal Shock Wave Therapy on Burns
Status: COMPLETED
Conditions: Burn Scar
Interventions: OTHER: Extracorporeal shock wave therapy|OTHER: conventional occupational therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Biological Effects of Quercetin in COPD
Status: RECRUITING
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Quercetin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Oxidative Stress in Response to Electroacupuncture Against Physical Activity in Diabetic Patients
Status: UNKNOWN
Conditions: Diabetes Mellitus, Type 2
Interventions: DEVICE: high intensity elliptical training|DEVICE: electrocaupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1/1b Study of IAM1363 in HER2 Cancers
Status: RECRUITING
Conditions: HER2 Mutation-Related Tumors
Interventions: DRUG: IAM1363|DRUG: Trastuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Role of Heme-oxygenase (HO) and Nitric Oxide (NO) Pathway in Patients With Obstructive Sleep Apnea (OSA) and Pulmonary Hypertension (PH)
Status: UNKNOWN
Conditions: Obstructive Sleep Apnea|Pulmonary Hypertension
Interventions: OTHER: measure exhaled carbon monoxide and nitric oxide
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical Study of Stent Versus Direct Atherectomy to Treat Iliac Artery Occlusive Diseases
Status: UNKNOWN
Conditions: Iliac Artery Occlusion
Interventions: DEVICE: stent|DEVICE: plaque excision system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Labetalol and Esmolol: Vital Signs and Post Operative Pain Management
Status: COMPLETED
Conditions: Laparoscopic Surgery
Interventions: DRUG: Fentanyl|DRUG: Labetalol|DRUG: Esmolol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Outcomes of the Hall Technique and Conventional Pulp Therapy for the Management of Caries in Primary Molars
Status: COMPLETED
Conditions: Deep Caries|Pulpitis - Reversible
Interventions: OTHER: Hall Technique|OTHER: Formecresol Pulpotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Minds and Mentors Program- R33
Status: RECRUITING
Conditions: Opioid Use Disorder|Substance Use Disorders|Medication Assisted Treatment
Interventions: BEHAVIORAL: Minds and Mentors|BEHAVIORAL: Twelve Step Intervention Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Oral Health Promotion Interventions Amongst Stroke Survivors During Rehabilitation
Status: COMPLETED
Conditions: Stroke
Interventions: DEVICE: Powered toothbrush|DEVICE: Manual toothbrush|OTHER: Toothpaste|OTHER: 0.2% chlorhexidine gluconate mouth rinse
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Levonorgestrel-Releasing Intrauterine System in Treating Patients With Complex Atypical Hyperplasia or Grade I Endometrial Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Atypical Endometrial Hyperplasia|Stage I Uterine Corpus Cancer AJCC v7|Stage IA Uterine Corpus Cancer AJCC v7|Stage IB Uterine Corpus Cancer AJCC v7|Stage II Uterine Corpus Cancer AJCC v7
Interventions: OTHER: Laboratory Biomarker Analysis|DEVICE: Levonorgestrel-Releasing Intrauterine System|OTHER: Quality-of-Life Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Standard Duodenal Switch vs. Single Anastomosis Duodeno-Ileostomy Duodenal Switch
Status: ACTIVE_NOT_RECRUITING
Conditions: Obesity|Surgery|Metabolic Syndrome|Malnutrition
Interventions: PROCEDURE: Duodenal Switch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of Lavender Oil on Vital Signs in Oral Surgery Patients
Status: COMPLETED
Conditions: Dental Anxiety|Sedative; Anxiety Disorder
Interventions: BEHAVIORAL: Inhalation|OTHER: Anxiety Questionnaires 1|OTHER: Anxiety Questionnaires 2|DIAGNOSTIC_TEST: Vital Signs 1|DIAGNOSTIC_TEST: Vital Signs 2|DIAGNOSTIC_TEST: Vital Signs 3|DIAGNOSTIC_TEST: Vital Signs 4
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Investigating the Effect of a Prenatal Family Planning Counseling Intervention Led by Community Health Workers on Postpartum Contraceptive Use Among Women in the West Bank
Status: COMPLETED
Conditions: Focus: Contraceptive Counseling|Focus: Postpartum Contraception
Interventions: OTHER: family planning counseling let by community health workers
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Effect of Dapagliflozin on Blood Pressure Variability in Prediabetes and Prehypertension
Status: COMPLETED
Conditions: PreDiabetes|Prehypertension
Interventions: DRUG: Dapagliflozin|DRUG: Placebo - Cap
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Activated Carbon Interphase Effect on Surgical Incisions vs.Two Common Wound Dressings
Status: WITHDRAWN
Conditions: Surgical Wound, Healed
Interventions: DEVICE: Activated Carbon Cloth Dressing|DEVICE: Knitted Cellulose Acetate Mesh|DEVICE: Antimicrobial Alginate Dressing with Silver
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of Vayarin in Children With Autism and Comorbid Attention Deficit Hyperactivity Disorder (ADHD)
Status: COMPLETED
Conditions: Autism Spectrum Disorder|Attention Deficit Hyperactivity Disorder
Interventions: DIETARY_SUPPLEMENT: Vayarin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Norepinephrine-ephedrine Combination on Maternal Hemodynamics
Status: UNKNOWN
Conditions: Cesarean
Interventions: OTHER: Ephedrine, Noradrenaline ,ephedrine+Noradrenaline)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Evaluation of Treatment Outcome of Lower Incisors Crowding Using Clear Aligners With Laser Acceleration .
Status: COMPLETED
Conditions: Tooth Movement
Interventions: PROCEDURE: Low-Level Laser acceleration|PROCEDURE: clear aligner therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Pharmacokinetic Drug-drug Interactions Between VX-548, Midazolam, and Digoxin
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: VX-548|DRUG: Midazolam|DRUG: Digoxin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Enhancing Capacity in Churches to Implement PA Programs
Status: RECRUITING
Conditions: Cardiovascular Diseases
Interventions: BEHAVIORAL: Faith in Action|BEHAVIORAL: Faith in Action+|BEHAVIORAL: Faith in Action++
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Effectiveness and Safety of Extended-Release (ER) Paliperidone Compared With Placebo in Delaying the Recurrence of Symptoms in Bipolar I Disorder
Status: COMPLETED
Conditions: Bipolar Disorder
Interventions: DRUG: Olanzapine|DRUG: Paliperidone ER|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Thorough QT (TQT) Study of CHF5993 pMDI in Healthy Volunteers (HV)
Status: COMPLETED
Conditions: Asthma|Chronic Obstructive Pulmonary Disease (COPD)
Interventions: DRUG: CHF5993|DRUG: CHF5259|DRUG: Moxifloxacin 400mg|DRUG: CHF5993 Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety Study for Refractory or Relapsed Neuroblastoma With DFMO Alone and in Combination With Etoposide
Status: COMPLETED
Conditions: Neuroblastoma
Interventions: DRUG: DFMO|DRUG: Etoposide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Exploring Two Treatment Strategies in Patients With Atrial Fibrillation Who Undergo Catheter Ablation Therapy
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DRUG: rivaroxaban|DRUG: uninterrupted vitamin K antagonist (VKA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Double-Blind, Placebo-Controlled Trial of Paromomycin for Treatment of Cryptosporidiosis in Patients With Advanced HIV Disease and CD4 Counts Under 150 Cells/mm3
Status: COMPLETED
Conditions: Cryptosporidiosis|HIV Infections
Interventions: DRUG: Paromomycin sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: Neurofeedback for Treatment-resistant Obsessive-compulsive Disorder (OCD)
Status: UNKNOWN
Conditions: Obsessive-Compulsive Disorder|OCD
Interventions: BEHAVIORAL: Real neurofeedback|BEHAVIORAL: Sham neurofeedback
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Early Detection of High Grade Ovarian Cancer Using Uterine Lavage EHUD Study and Duplex Sequencing
Status: COMPLETED
Conditions: Ovarian Epithelial Cancer|Carcinoma in Situ|Ovarian Cancer
Interventions: PROCEDURE: Speiser-catheter for uterine and tubal lavage
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Mechanistic Clinical Trial of Colchicine in Patients Undergoing Femoral Endarterectomy
Status: NOT_YET_RECRUITING
Conditions: Peripheral Artery Disease
Interventions: DRUG: Colchicine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Efficacy and Safety of Clostridium Botulinum Toxin Type A to Improve Appearance of Moderate to Severe Glabellar Lines
Status: COMPLETED
Conditions: Moderate to Severe Glabellar Lines
Interventions: BIOLOGICAL: Botulinum toxin type A|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intralesional Injection of Combined Digoxin and Furosemide Versus 5-Flurouracil in Plantar Warts
Status: NOT_YET_RECRUITING
Conditions: Plantar Wart
Interventions: DRUG: intralesional combined digoxin and furosemide|DRUG: intralesional injection of 5- Fluorouracil|OTHER: intralesional saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Reducing Sexual Risk Behaviors and Improving Health for People at a Sexually Transmitted Infection Clinic
Status: COMPLETED
Conditions: HIV|Sexually Transmitted Diseases|HIV Infections
Interventions: BEHAVIORAL: DVD 1|BEHAVIORAL: DVD 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Voice-activated Intelligent Personal Assistant (VIPA) Intervention for People With Parkinson's Disease
Status: RECRUITING
Conditions: Parkinson's Disease and Parkinsonism
Interventions: DEVICE: Voice-activated Intelligent Personal Assistant (VIPA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Venetoclax and a Pediatric-Inspired Regimen for the Treatment of Newly Diagnosed B Cell Acute Lymphoblastic Leukemia
Status: ACTIVE_NOT_RECRUITING
Conditions: B Acute Lymphoblastic Leukemia|Ph-Like Acute Lymphoblastic Leukemia
Interventions: DRUG: Cyclophosphamide|DRUG: Cytarabine|DRUG: Daunorubicin Hydrochloride|DRUG: Mercaptopurine|DRUG: Methotrexate|DRUG: Pegaspargase|DRUG: Prednisone|DRUG: Venetoclax|DRUG: Vincristine Sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Implantable Tibial Neuromodulation (TITAN 1) Feasibility Study
Status: COMPLETED
Conditions: Overactive Bladder
Interventions: DEVICE: Medtronic Implantable Tibial Neuromodulation (TNM) System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Proteasome Inhibitor PS-341 Relapsed or Refractory B Cell Lymphomas Previously Treated With Chemotherapy
Status: COMPLETED
Conditions: Lymphoma, B-Cell
Interventions: DRUG: PS341 (Bortezomib)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Prednisolone and Dexamethasone on Mortality in Patients on Oxygen Therapy, With CoViD-19
Status: COMPLETED
Conditions: Coronavirus Infection
Interventions: DRUG: DEXAMETHASONE|DRUG: PREDNISOLONE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of IntraSPINE® Associated With Discectomy in the Treatment of Lumbar Disc Herniation.
Status: UNKNOWN
Conditions: Disk Herniated Lumbar
Interventions: DEVICE: Insertion of INTRASPINE device|PROCEDURE: Discectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effects of L-thyroxine Replacement on Serum Lipid and Atherosclerosis in Hypothyroidism
Status: UNKNOWN
Conditions: Hypothyroidism|Thyroid Diseases|Endocrine System Diseases
Interventions: DRUG: L-thyroxine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics of HR17031 Injection in Healthy Subjects
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: HR17031 injection ；INS068 injection；SHR20004 injection|DRUG: HR17031 injection ；INS068 injection；SHR20004 injection|DRUG: HR17031 injection ；INS068 injection；SHR20004 injection|DRUG: HR17031 injection ；INS068 injection；SHR20004 injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevention of Asthma Exacerbations Using Dupilumab in Urban Children and Adolescents
Status: RECRUITING
Conditions: Asthma
Interventions: DRUG: Dupilumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Study To Evaluate Antiviral Activity Of Small Molecule Direct Antiviral Agent At Multiple Doses In Subjects With Chronically Infected Hepatitis C Virus.
Status: COMPLETED
Conditions: Hepatitis, Chronic|Hepatitis C Virus
Interventions: DRUG: Small Molecule Agent (PF-868554)|DRUG: Small Molecule Agent (PF-868554)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Proprioseptive Vestibular Rehabilitation in Patients With Peripheral Vestibular Hypofunction
Status: COMPLETED
Conditions: Vertigo, Peripheral|Vestibular Disease
Interventions: OTHER: Proprioceptive vestibular exercise|OTHER: Standard vestibular rehabilitation exercises|OTHER: Controlled
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Nadolol Versus Propranolol in Children With Infantile Hemangiomas
Status: COMPLETED
Conditions: Infantile Hemangioma
Interventions: DRUG: Nadolol|DRUG: Propranolol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of Inspiratory Muscle Rest and Exercise in Chronic Obstructive Lung Disease
Status: COMPLETED
Conditions: Lung Diseases|Lung Diseases, Obstructive|Chronic Obstructive Pulmonary Disease
Interventions: DEVICE: ventilators, negative pressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: A 14-Month Study On The Effects Of CP-945,598 For The Prevention Of Weight Regain In Obese Patients
Status: TERMINATED
Conditions: Obesity
Interventions: DRUG: CP-945,598|BEHAVIORAL: Non-pharmacological weight loss program (NPP)|BEHAVIORAL: Low Calorie Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Nitrates and Citrulline Malate on Performance in Professional Professional Soccer
Status: COMPLETED
Conditions: Supplementation
Interventions: DIETARY_SUPPLEMENT: Nitrates and Citrulline Malate|DIETARY_SUPPLEMENT: Control product
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Oncolytic Virus Plus PD-1 Inhibitor to Patients With Advanced Pancreatic Cancer
Status: NOT_YET_RECRUITING
Conditions: Pancreatic Cancer
Interventions: DRUG: H101|DRUG: Camrelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 31P-MRS Imaging to Assess the Effects of CNM-Au8 on Impaired Neuronal Redox State in Multiple Sclerosis.
Status: RECRUITING
Conditions: Multiple Sclerosis
Interventions: DRUG: gold nanocrystals
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral Versus Vaginal Progesterone for Luteal Phase Supplementation in Frozen Embryo Transfer Cycles
Status: COMPLETED
Conditions: Frozen Embryo Transfer|Hormone Replacement Therapy|Dydrogesterone|Infertility, Female
Interventions: DRUG: Dydrogesterone 10 MG Oral Tablet|DRUG: Micronized progesterone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Visual Function After Bilateral Implantation of Presbyopia-correcting Intraocular Lenses (IOLs)
Status: COMPLETED
Conditions: Cataract
Interventions: DEVICE: ReSTOR +3|DEVICE: Tecnis MF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Interpersonal Psychotherapy on Quality of Life Among People Living With HIVAIDS
Status: COMPLETED
Conditions: Breif Description: Patients' Quality of Life of
Interventions: BEHAVIORAL: Interpersonal Psychotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Post COVID-19 REspiratory Mechanisms and the Efficacy of a Breathing Exercise Intervention for DYsregulated Breathing
Status: ACTIVE_NOT_RECRUITING
Conditions: COVID-19|Respiratory Disease
Interventions: OTHER: Breathing techniques over 12 sessions / 6 weeks inc yoga
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence of a Fixed Dose Combination Tablet of Empagliflozin/Linagliptin Compared With the Free Combination of Empagliflozin Tablet and Linagliptin Tablet in Healthy Male and Female Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Empagliflozin|DRUG: Linagliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fluticasone Propionate-salmeterol Combination Adherence in Patients With Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: fluticasone propionate/salmeterol xinafoate combination
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Autologous Mesenchymal Stem Cells From Adipose Tissue in Patients With Secondary Progressive Multiple Sclerosis
Status: COMPLETED
Conditions: Autoimmune Diseases|Immune System Diseases|Demyelinating Diseases|Nervous System Diseases|Demyelinating Autoimmune Diseases, CNS|Autoimmune Diseases of the Nervous System
Interventions: OTHER: Autologous mesenchymal stem cells from adipose tissue.|OTHER: Autologous mesenchymal stem cells from adipose tissue.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of 3D Overlay During Transjugular Intrahepatic Portosystemic Shunt (TIPS) Procedure
Status: COMPLETED
Conditions: Portal Hypertension
Interventions: PROCEDURE: TIPS with 3D Overlay
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Evaluation of the Effect of Preoperatively Applied Throat Lozenge
Status: COMPLETED
Conditions: Anesthesia|Pain, Postoperative
Interventions: OTHER: strepsilis|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Single-arm, Multicenter Study to Assess the Efficacy, Safety, and Tolerability of P1101 in Adults With ET
Status: RECRUITING
Conditions: Essential Thrombocythemia
Interventions: DRUG: Ropeginterferon alfa-2b-njft (P1101)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dietary Supplementation With Omega-3 Fatty Acid in Muscle Response
Status: UNKNOWN
Conditions: Elderly Women|Sarcopenia
Interventions: DRUG: Fish oil|DRUG: sunflower oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Effect of a Gait Retraining Intervention and a Minimalist Footwear Transition on Foot-ankle Strength, Running Economy and Injury in Endurance Runners.
Status: ENROLLING_BY_INVITATION
Conditions: Running|Wounds and Injuries|Oxygen Consumption
Interventions: BEHAVIORAL: Gait retraining intervention|DEVICE: Transition to minimalist footwear.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Immunogenicity and Safety Study to Assess Influenza Vaccine Formulated With Haemagglutinin (HA) Antigen From Two Suppliers
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Inflexal V influenza vaccine (CSL HA Antigen) 2010|BIOLOGICAL: Inflexal V influenza vaccine (AdImmune HA antigen) 2010/2011
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Clinico-Bacteriological Study and Effect of Stress Ulcer Prophylaxis on Occurrence of Ventilator Associated Pneumonia
Status: COMPLETED
Conditions: Ventilator Associated Pneumonia|Etiological Organisms|Antimicrobial Drug Susceptibility Pattern|Stress Ulcer Prophylaxis
Interventions: DRUG: Ranitidine|DRUG: Sucralfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Spinal Morphine for Patients With Obstructive Sleep Apnea
Status: SUSPENDED
Conditions: Obstructive Sleep Apnea
Interventions: DRUG: Intrathecal Morphine|DRUG: No Intrathecal Morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dabigatran Etexilate vs Enoxaparin in Prevention of Venous Thromboembolism (VTE) Post Total Knee Replacement
Status: COMPLETED
Conditions: Arthroplasty, Replacement, Knee|Thromboembolism
Interventions: DRUG: Dabigatran Dose 1 - day 2 to completion|DRUG: Dabigatran Dose 1 - day 1|DRUG: Dabigatran Dose 2 - day 2 to completion|DRUG: Dabigatran Dose 2 - day 1|DRUG: Enoxaparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: MK0431 and Pioglitazone Co-Administration Factorial Study in Patients With Type 2 Diabetes Mellitus (0431-102 AM2)
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Sitagliptin phosphate|DRUG: Pioglitazone hydrochloride|DRUG: Matching placebo to sitagliptin|DRUG: Matching placebo to pioglitazone|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Omega-3 on Selected Cytokines Involved in Cytokine Storm
Status: COMPLETED
Conditions: Cytokine Storm|Cytokines
Interventions: DIETARY_SUPPLEMENT: 300 mg of omega3-FA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Phase 2B Dose-Ranging Study of PAC113 Mouthrinse in HIV Seropositive Individuals With Oral Candidiasis
Status: COMPLETED
Conditions: Oral Candidiasis
Interventions: DRUG: PAC113
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: To Demonstrate Equivalence of Pharmacokinetics and Noninferiority of Efficacy for CT-P10 in Comparison With Rituxan
Status: COMPLETED
Conditions: Lymphoma, Follicular
Interventions: BIOLOGICAL: Rituxan|BIOLOGICAL: CT-P10|DRUG: Cyclophosphamide|DRUG: Vincristine|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Virtual Peer-to-Peer (VP2P) Support Mentoring for Adolescents With Cancer
Status: COMPLETED
Conditions: Cancer
Interventions: BEHAVIORAL: Virtual Peer-to-Peer Support Mentoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study Evaluating FMC-376 in Participants With KRAS G12C Mutated Solid Tumors
Status: RECRUITING
Conditions: Advanced Solid Tumors With KRAS G12C Mutations|Solid Tumor, Adult|Unresectable Solid Tumor|Metastatic Solid Tumor|Non Small Cell Lung Cancer|Colorectal Cancer|KRAS G12C|Pancreatic Cancer
Interventions: DRUG: FMC-376
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Clinical Benefit and Safety of Droxidopa in Parkinson's Disease
Status: UNKNOWN
Conditions: Parkinson's Disease|Freezing of Gait|Cognitive Ability, General
Interventions: DRUG: Droxidopa|DRUG: sugar pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Combined Trab+Trab Versus Combined Trab+Trab With Subconjunctival Implantation of Ologen for Primary Congenital Glaucoma
Status: UNKNOWN
Conditions: Congenital Glaucoma
Interventions: DEVICE: Ologen Collagen Matrix|PROCEDURE: Combined trabeculotomy-trabeculectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Research Evaluating an Investigational Medication for Erectile Dysfunction - Diabetic ED (REVIVE-D)
Status: COMPLETED
Conditions: Erectile Dysfunction
Interventions: DRUG: placebo|DRUG: avanafil|DRUG: avanafil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Topical Antipsoriatics in the Psoriasis Plaque Test
Status: COMPLETED
Conditions: Psoriasis Vulgaris
Interventions: DRUG: Protopic, Advantan|PROCEDURE: Blood and Urine Test|PROCEDURE: coherence tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of XyloCore Peritoneal Dialysis Solution.
Status: RECRUITING
Conditions: End Stage Renal Disease
Interventions: DRUG: XyloCore Low Strenght, XyloCore Medium Strenght, XyloCore High Strenght|DRUG: 1.36%, 1.5%, 2.27%, 2.5%, 3.86%, 2.25% Glucose PD Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Long-term Treatment With Deferasirox in Patients With Beta-thalassemia and Transfusional Hemosiderosis
Status: COMPLETED
Conditions: Beta-Thalassemia|Hemosiderosis
Interventions: DRUG: deferasirox
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bevacizumab, Fluorouracil, Leucovorin Calcium, and Oxaliplatin Before Surgery in Treating Patients With Stage II-III Rectal Cancer
Status: UNKNOWN
Conditions: Mucinous Adenocarcinoma of the Rectum|Signet Ring Adenocarcinoma of the Rectum|Stage IIA Rectal Cancer|Stage IIB Rectal Cancer|Stage IIC Rectal Cancer|Stage IIIA Rectal Cancer|Stage IIIB Rectal Cancer|Stage IIIC Rectal Cancer
Interventions: BIOLOGICAL: bevacizumab|DRUG: oxaliplatin|DRUG: leucovorin calcium|DRUG: fluorouracil|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trunk Rehabilitation Compared to Core Stability in Patients With Multiple Sclerosis
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Sclerosis|Trunk|Physical Therapy
Interventions: OTHER: Trunk Rehabilitation|OTHER: Core Stability
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Antidepressant Augmentation With Lamotrigine
Status: COMPLETED
Conditions: Depression
Interventions: DRUG: Lamotrigine|DIETARY_SUPPLEMENT: Amide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of MT-5199 in Subjects With Tardive Dyskinesia
Status: COMPLETED
Conditions: Tardive Dyskinesia
Interventions: DRUG: MT-5199|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Oral Propranolol Versus Placebo for Early Stages of Retinopathy of Prematurity: A Randomized and Prospective Study
Status: COMPLETED
Conditions: Retinopathy of Prematurity
Interventions: DRUG: propranolol|DRUG: sucrose 5%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Brillant Blue Versus Indocyanine Green for Macular Hole Surgery
Status: COMPLETED
Conditions: Idiopathic Macular Holes
Interventions: PROCEDURE: Brillant Blue|PROCEDURE: Indocyanine Green
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ESCAPE Migraine Trial
Status: TERMINATED
Conditions: Migraine Disorders|Heart Septal Defects, Atrial
Interventions: DEVICE: PFO Closure with Premere investigational device.|DRUG: Medical management/current medications per standard of care by personal physician.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ph3 Study To Determine Safety,Tolerability&Tumor Response Of Oraxol Compared To Taxol In Metastatic Breast Cancer
Status: COMPLETED
Conditions: Metastatic Breast Cancer
Interventions: DRUG: Oraxol|DRUG: IV paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase II Trial of Early Medical Adrenalectomy for "D0.5" Prostate Cancer
Status: TERMINATED
Conditions: Prostate Cancer
Interventions: DRUG: aminoglutethimide|DRUG: ketoconazole|DRUG: therapeutic hydrocortisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Learn More About the Study Medicine Called Inotuzumab Ozogamicin (InO) in Children (1 to <18 Years) With First Relapse ALL
Status: RECRUITING
Conditions: ACUTE LYMPHOBLASTIC LEUKEMIA
Interventions: DRUG: Inotuzumab ozogamicin|DRUG: ALLR3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acute Changes in the Mineral Metabolism After a High Phosphorous Containing Meal in Dialysis Patients
Status: COMPLETED
Conditions: Chronic Kidney Disease Stage 5|Mineral Metabolism Disorder
Interventions: DIETARY_SUPPLEMENT: High phosphorous containing meal|DIETARY_SUPPLEMENT: Low phosphorous containing meal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Study of Mometasone Furoate Metered Dose Inhaler in Children With Persistent Asthma (P04223)
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Mometasone Furoate (MF) Metered Dose Inhaler (MDI), 25 mcg|DRUG: Mometasone Furoate (MF) Metered Dose Inhaler (MDI), 50 mcg|DRUG: Mometasone Furoate (MF) Metered Dose Inhaler (MDI), 100 mcg|DRUG: Mometasone Furoate (MF) Dry Powder Inhaler (DPI), 100 mcg|DRUG: Placebo Metered Dose Inhaler (MDI)|DRUG: Placebo Dry Powder Inhaler (DPI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: OCL 500 Treatment of Women With Symptomatic Uterine Fibroids
Status: COMPLETED
Conditions: Uterine Fibroid|Myoma|Leiomyoma
Interventions: DEVICE: Occlusin 500 Microspheres
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Efficacy and Safety of CJM112 in Patients With Moderate to Severe Inflammatory Acne
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: BIOLOGICAL: CJM112|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Longitudinal Monitoring of Microsurgical Socket Augmentation Healing With Ultrasonography
Status: COMPLETED
Conditions: Healing Wound
Interventions: DEVICE: Orascopic HDL 3.0 Loupes|DEVICE: Semorr DOM3000D Operation Microscope
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tandem Auto-Allo Transplant for Lymphoma
Status: COMPLETED
Conditions: Diffuse, Large B-Cell, Lymphoma|Lymphoma, Low-Grade|T-Cell Lymphoma|Mantle-Cell Lymphoma|Hodgkin's Lymphoma|Chronic Lymphocytic Leukemia|Lymphoma, Small Lymphocytic
Interventions: DRUG: Busulfan (conditioning for AUTO transplant)|DRUG: Etoposide (conditioning for AUTO transplant)|DRUG: Cyclophosphamide (conditioning for AUTO transplant)|DRUG: Mesna (prior to AUTO transplant)|OTHER: autologous (auto) peripheral blood stem cell transplantation|DRUG: Neupogen|DRUG: Fludarabine (conditioning for ALLO Transplant)|DRUG: Busulfan (conditioning for ALLO Transplant)|OTHER: non-myeloablative allogeneic (allo) transplant|DRUG: Tacrolimus|DRUG: Sirolimus|DRUG: Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BMAC & Allograft vs BMP-2
Status: ACTIVE_NOT_RECRUITING
Conditions: Spinal Fusion
Interventions: DEVICE: Bone Marrow Aspirate Concentrate (BMAC) + Allograft|DEVICE: Recombinant Human Bone Morphogenetic Protein-2 (BMP)|PROCEDURE: Autograft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Thoracic Manipulation Versus Myofascial Release in Patients With Shoulder Impingement Syndrome
Status: UNKNOWN
Conditions: Impingement Shoulder
Interventions: OTHER: scapular stabilization exercises.|OTHER: Thoracic manipulation.|OTHER: Myofascial release.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Multi-Center Clinical Trial to Determine the Impact of a Mobile Health Application on Rheumatoid Arthritis Shared Decision Making
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: BEHAVIORAL: Mobile Health App
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study to Test the Safe and Effective Use of an e-Device for the Self-injection of Certolizumab Pegol Solution by Subjects With Moderate to Severe Active Rheumatoid Arthritis, Active Ankylosing Spondylitis, Active Psoriatic Arthritis, or Moderately to Severely Active Crohn's Disease
Status: COMPLETED
Conditions: Moderate and Severe Active Rheumatoid Arthritis|Active Psoriatic Arthritis|Active Ankylosing Spondylitis|Moderately to Severely Active Crohn's Disease
Interventions: DRUG: e-Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study for Participants Continuing From Pfizer-sponsored Palbociclib (a Study Medicine) Studies
Status: RECRUITING
Conditions: Breast Cancer|Head and Neck Cancer
Interventions: DRUG: Palbociclib|DRUG: Cetuximab|DRUG: Fulvestrant|DRUG: Letrozole
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: T Cell Receptor (TCR) Sequencing and Transcriptional Profiling in Adult Celiac Disease Patients Undergoing Gluten Challenge
Status: COMPLETED
Conditions: Celiac Disease
Interventions: DIETARY_SUPPLEMENT: Gluten Powder
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Transcutaneous Spinal Cord Stimulation to Promote Walking Recovery After Spinal Cord Injury
Status: RECRUITING
Conditions: Spinal Cord Injuries
Interventions: DEVICE: Exo + TSCS|DEVICE: Exo + Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Peanut Oral Immunotherapy in Children
Status: COMPLETED
Conditions: Peanut Hypersensitivity
Interventions: BIOLOGICAL: Peanut Oral Immunotherapy - Liquid Extract|BIOLOGICAL: Placebo for Peanut Oral Immunotherapy - Liquid Extract form|BIOLOGICAL: Peanut Oral Immunotherapy - Peanut Flour|BIOLOGICAL: Placebo for Peanut Oral Immunotherapy - Peanut Flour
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Health Benefits of Air Purifiers in Primary School Students
Status: UNKNOWN
Conditions: Cardiopulmonary Function|Child
Interventions: BEHAVIORAL: Air purifier and fresh air ventilation systems with high-efficiency particulate air (HEPA) filters|BEHAVIORAL: Air purifier and fresh air ventilation systems without high-efficiency particulate air (HEPA) filters
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Intra-arterial Stem Cell Therapy for Patients With Chronic Limb Ischemia (CLI)
Status: COMPLETED
Conditions: Peripheral Vascular Diseases|Arterial Occlusive Diseases|Leg Ulcer|Gangrene|Ischemia
Interventions: PROCEDURE: Bone marrow punction|PROCEDURE: BM-MNC infusion|PROCEDURE: Placebo infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Prospective Evaluation of the Catheter Science C3 "Umbrella Catheter."
Status: UNKNOWN
Conditions: Urinary Retention|Urinary Bladder, Neurogenic|Intermittent Catheterization
Interventions: DEVICE: C3 "UMBRELLA CATHETER"
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Behavioural Science Messages in Breast Cancer Screening
Status: COMPLETED
Conditions: Breast Cancer
Interventions: BEHAVIORAL: Behavioural Message|BEHAVIORAL: Behavioural Message + Video|OTHER: Usual Care Message
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: SCREENING
Clinical trial: Psychosocial Mobile App for Chronic Graft-Versus-Host Disease
Status: RECRUITING
Conditions: Chronic Graft-Versus-Host Disease|Allogeneic Stem Cell Transplant
Interventions: BEHAVIORAL: App|BEHAVIORAL: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Laparoscopic Bariatric Surgery to Treat Type 2 Diabetes in Obese Patients
Status: TERMINATED
Conditions: Type 2 Diabetes
Interventions: PROCEDURE: laparoscopic gastric bypass surgery|PROCEDURE: laparoscopic adjustable gastric banding|PROCEDURE: Intensive Medical Management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Zuojin Wan Combined With Rabeprazole or Mosapride for the Treatment of Functional Dyspepsia Combined With Depression
Status: NOT_YET_RECRUITING
Conditions: Functional Dyspepsia|Depression
Interventions: DRUG: zuojinwan|DRUG: Rabeprazole sodium enteric-coated tablets|DRUG: mosapride citrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of Two Botulinum Toxins Type A on Forehead Wrinkles
Status: COMPLETED
Conditions: Wrinkles
Interventions: DRUG: Botulinum Toxin Type A - Azzalure|DRUG: Botulinum Toxin Type A - Vistabel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Recombinant Humanized Anti-CD47 / PD-1 Bifunctional Antibody HX009 Injection in the Treatment of Advanced Solid Tumors
Status: UNKNOWN
Conditions: Advanced Solid Tumor
Interventions: DRUG: HX009
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RCT of an Oral Acne Supplement for Adult Women
Status: RECRUITING
Conditions: Acne
Interventions: DIETARY_SUPPLEMENT: Skin Nutraceutical Supplement|OTHER: Placebo pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Crossover Study to Evaluate Relative Bioavailability of Simeprevir Age-appropriate Oral Formulation Candidates Compared With 150-milligram (mg) Oral Capsule in Healthy Adult Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Treatment A|DRUG: Treatment B|DRUG: Treatment C|DRUG: Treatment D|DRUG: Treatment E|DRUG: Treatment F
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Socket Augmentation Using Atorvastatin With Or Without PRGF (Clinical and Histomorphometric Study)
Status: COMPLETED
Conditions: Socket Preservation
Interventions: DRUG: PRGF/ATV|DRUG: ATV gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Long-Term Safety of Renzapride in Women With Constipation-Predominant Irritable Bowel Syndrome (IBS-C)
Status: TERMINATED
Conditions: Constipation-Predominant Irritable Bowel Syndrome
Interventions: DRUG: Renzapride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Personalized Screening Plans to Increase Colorectal Cancer Screening in Healthy Participants
Status: UNKNOWN
Conditions: Colorectal Cancer
Interventions: OTHER: medical chart review|OTHER: survey administration|PROCEDURE: fecal occult blood test|PROCEDURE: screening colonoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: SINGLE|Primary Purpose: HEALTH_SERVICES_RESEARCH