pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Effect of Early Eating and BCAA Supplementation on Body Composition
Status: NOT_YET_RECRUITING
Conditions: eTRE (Early Time Restricted Eating) With BCAA|eTRE (Early Time Restricted Eating)
Interventions: BEHAVIORAL: Time Restricted Eating
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lantus Versus NPH: Comparison in Insulin Naive People Not Adequately Controlled With at Least One Oral Anti Diabetics (OAD) Treatment
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Insulin Glargine (HOE901) [Lantus]|DRUG: Glimepiride|DRUG: human insulin [NPH]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess Safety and Efficacy of DF01 in Reducing Prolonged Labor
Status: COMPLETED
Conditions: Pregnancy|Labor
Interventions: DRUG: DF01|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Dose Finding Study of IDH305 With Standard of Care in IDH1 Mutant Acute Myeloid Leukemia
Status: WITHDRAWN
Conditions: Acute Myeloid Leukemia (AML)
Interventions: DRUG: IDH305
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Spread of Muscle Hyperalgesia and Pain in a Low Dose NGF-induced Pain Model
Status: COMPLETED
Conditions: Hyperalgesia|Healthy Subjects
Interventions: DRUG: NGF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Phase II Trial of XP Versus XG in Advanced Esophageal Squamous Cell Carcinoma
Status: COMPLETED
Conditions: Advanced or Recurrent Esophageal Squamous Cell Carcinoma
Interventions: DRUG: Capecitabine/Cisplatin(XP)|DRUG: Capecitabine/Paditaxel(XG)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The FLOT Regimen Conversion Therapy of Adenocarcinoma of the Stomach / Gastroesophageal
Status: UNKNOWN
Conditions: Adenocarcinoma of the Stomach / Gastroesophageal
Interventions: DRUG: FLOT regimen chemotherapy|PROCEDURE: D2 gastric and imaging metastases resection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Comfort & Ocular Surface Parameters w Novel Designs of Daily Disposable Silicone Hydrogel Contact Lenses
Status: COMPLETED
Conditions: Visual Acuity|Contact Lens Comfort
Interventions: DEVICE: Menicon Modified Lens Design
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Docetaxel Monotherapy or DOXIL and Docetaxel in Patients With Advanced Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Docetaxel|DRUG: DOXIL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Total Thyroidectomy on Voice and Swallowing
Status: UNKNOWN
Conditions: Thyroidectomy|Voice Alteration|Swallowing Alteration
Interventions: OTHER: Endoscopy of larynx|OTHER: Voice Handicap Index|OTHER: Swallowing Assesment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Efficacy of GSMs-TACE Combined With Surgical Resection in the Treatment of Hepatocellular Carcinoma (HCC) With Type III Portal Vein Tumor Thrombus (PVTT)
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma (HCC) With Type III Portal Vein Tumor Thrombus (PVTT)
Interventions: DEVICE: GSMs-TACE|PROCEDURE: Surgical Resection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess Immune Responses and Safety of the GSK-580299 Vaccine in Healthy Women (26 to 45 Years)
Status: COMPLETED
Conditions: Infections, Papillomavirus
Interventions: BIOLOGICAL: GSK580299 (CervarixTM)|BIOLOGICAL: Engerix-BTM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Phase 2 Study Evaluating Olutasidenib in Patients With IDH1-mutated Clonal Cytopenia of Undetermined Significance and Lower-risk Myelodysplastic/Syndromes/Chronic Myelomonocytic Leukemia.
Status: NOT_YET_RECRUITING
Conditions: Myelodysplastic Syndromes|Chronic Myelomonocytic Leukemia|Clonal Cytopenia of Undetermined Significance
Interventions: DRUG: Olutasidenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Transbronchial Cryobiopsy and Forceps Biopsy in Lung Transplant Recipients
Status: COMPLETED
Conditions: Lung Transplant Rejection|Lung Transplant Failure and Rejection
Interventions: PROCEDURE: CB study arm|PROCEDURE: FB-CB study arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Tacrolimus Ointment in Oral Lichen Planus
Status: TERMINATED
Conditions: Oral Lichen Planus
Interventions: DRUG: 0.1 % tacrolimus ointment|DRUG: 0.1 % triamcinolone paste|DRUG: Orabase paste
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Efficacy and Safety of Daily Oral TAK-875 25 and 50mg in Asia Pacific Adults With Type 2 Diabetes
Status: TERMINATED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: TAK-875|DRUG: TAK-875 Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Routine Versus Symptomatic Protein Pump Inhibitor Therapy for Prevention of Gastroesophageal Reflux After Per Oral Endoscopic Myotomy for Esophageal Achalasia
Status: RECRUITING
Conditions: Esophageal Achalasia
Interventions: DRUG: Protein pump inhibitor therapy systematically
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Identification in Obese Patients of the Mechanism Involved in Intramuscular Lipid Accumulation
Status: COMPLETED
Conditions: Obesity|Insulin Resistance|Hyperlipidemia
Interventions: OTHER: Lipid accumulation analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Improving Tolerance of Treatment of Pulmonary MAC Infections
Status: WITHDRAWN
Conditions: Mycobacterium Avium Complex|Adverse Effects
Interventions: DRUG: Zofran (8mg)|DIETARY_SUPPLEMENT: Ensure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Drug-Drug Interaction Between Colchicine and Verapamil ER
Status: COMPLETED
Conditions: Pharmacokinetics
Interventions: DRUG: Colchicine|DRUG: Verapamil HCl ER|DRUG: Colchicine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of TMC647055 in Combination With Ritonavir (Part 1) and the Co-administration of TMC435, TMC647055 and Ritonavir (Part 2) in Healthy Japanese Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: TMC647055|DRUG: TMC435|DRUG: Placebo|DRUG: Ritonavir (RTV)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Hemodynamic Comparison of Stationary and Portable Pneumatic Compression Devices
Status: COMPLETED
Conditions: Total Hip Arthroplasty
Interventions: DEVICE: ActiveCare+SFT Supine|DEVICE: VenaFlow Elite Supine|DEVICE: ActiveCare+SFT Standing|DEVICE: VenaFlow Elite Standing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: BLINAtumomab After R-CHOP Debulking Therapy for Patients With Richter Transformation
Status: COMPLETED
Conditions: Richter Syndrome
Interventions: DRUG: RCHOP|DRUG: Blinatumomab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare the Safety and Efficacy of Dysport® and Botox® in Adults With Upper Limb Spasticity.
Status: RECRUITING
Conditions: Upper Limb Spasticity
Interventions: BIOLOGICAL: AboBoNT-A|BIOLOGICAL: OnaBoNT-A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study of TQB3912 Tablets in Patients With Advanced Malignant Tumor
Status: NOT_YET_RECRUITING
Conditions: Advanced Malignant Neoplasm
Interventions: DRUG: TQB3912 tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: rTMS Target Identification for Functional Disability in AUD+mTBI
Status: RECRUITING
Conditions: Alcohol Use Disorder|Mild Traumatic Brain Injury
Interventions: DEVICE: Magventure MagProX100 with MagOption stimulator and Magpro Cool Coil B65 A/P
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sirolimus Blood Concentrations on Conversion From Oral Solution to Tablets
Status: UNKNOWN
Conditions: Transplantation|Kidney Transplantation|Immunosuppression
Interventions: DRUG: sirolimus, cyclosporine, tacrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy of 500µg Roflumilast Once Daily Versus Placebo Over 12 Weeks in Patients With Diabetes Mellitus Type 2. A Double Blind, Parallel Group, Proof of Concept Clinical Study
Status: COMPLETED
Conditions: Diabetes Mellitus Type 2
Interventions: DRUG: Roflumilast
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Levcromakalim in Individuals With Migraine Pretreated With Erenumab
Status: COMPLETED
Conditions: Migraine Without Aura
Interventions: DRUG: Levcromakalim|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Non-interventional Study Describing Epidemiology, Prognosis and Patient Healthcare Costs in France, 2010-2017
Status: UNKNOWN
Conditions: Lung Diseases, Interstitial|Lung Disease With Systemic Sclerosis
Interventions: OTHER: epidemiology, healthcare costs in non-IPF PF-ILD and SSc-ILD
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical Trial on Ceramic Partial Laminate Veneers With Different Luting Agents
Status: ENROLLING_BY_INVITATION
Conditions: Healthy
Interventions: PROCEDURE: Conventional Resin Cement vs Preheated Resin Composite
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Chinese Medicine and Lactobacillus in Persistent HPV Infection
Status: RECRUITING
Conditions: Human Papilloma Virus Infection
Interventions: DRUG: Chinese medicine and Lactobacillus|DRUG: Chinese medicine|DRUG: Lactobacillus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cytokines of Patients With Transversus Abdominis Plane Block After Laparoscopic Colonic Surgery
Status: COMPLETED
Conditions: Laparoscopic Colonic Surgery
Interventions: DRUG: transversus abdominis plane block|DRUG: transversus abdominis plane block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Pharmacokinetics Study to Evaluate Safety and Tolerability of JNJ-37822681 in Participants With Stable Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: JNJ-37822681|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: B.R.A.I.N in People Living With HIV Study
Status: RECRUITING
Conditions: HIV-associated Neurocognitive Disorders
Interventions: BEHAVIORAL: Combined Cognitive Symptom Management and Rehabilitation Therapy (CogSMART) and BrainHQ©
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Relative Bioavailability Study of Amlodipine Besylate 10 mg Tablets Under Fasting Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: AMLODIPINE (as BESILATE) TABLETS 10 mg , single dose|DRUG: Norvasc® 10 mg Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Effect of Vitamin B12 Supplementation on Glycaemic Control in Uncontrolled Hyperhomocysteinemic Type 2 Diabetic Patients
Status: COMPLETED
Conditions: Type 2 Diabetes|Vitamin B12 Deficiency|Hyperhomocysteinemia
Interventions: DIETARY_SUPPLEMENT: METHYLCOBALAMIN 500 micrograms
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Topical Fluorescent Nanoparticles Conjugated Somatostatin Analog for Suppression and Bioimaging Breast Cancer
Status: UNKNOWN
Conditions: Breast Cancer|Skin Cancer|Skin Diseases
Interventions: DRUG: Quantum dots coated with veldoreotide|DRUG: Topical approved placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Ignite Pilot: Goal Setting in a Digital Weight Loss Intervention
Status: COMPLETED
Conditions: Obesity|Overweight|Weight Loss|Health Behavior
Interventions: BEHAVIORAL: Core Behavioral Weight Loss Intervention|BEHAVIORAL: Easier Step Goal|BEHAVIORAL: Harder Step Goal|BEHAVIORAL: Easier Calorie Goal|BEHAVIORAL: Harder Calorie Goal|BEHAVIORAL: Easier Eating Window Goal|BEHAVIORAL: Harder Eating Window Goal|BEHAVIORAL: Easier Red Zone Food Goal|BEHAVIORAL: Harder Red Zone Food Goal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phytocannabinoids for the Treatment of Chronic Chemotherapy-Induced Peripheral Neuropathy in Breast and Colon Cancer Survivors
Status: WITHDRAWN
Conditions: Breast Carcinoma|Chemotherapy-Induced Peripheral Neuropathy|Colon Carcinoma
Interventions: DRUG: Cannabidiol|DRUG: Delta-8-Tetrahydrocannabinol|DRUG: Placebo Administration|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Pre and Post Test Intervention Design to Prevent Abortion and Contraceptive-use Stigma Among School Youths in Kenya
Status: COMPLETED
Conditions: Social Stigma|Pregnancy|Contraception
Interventions: BEHAVIORAL: Abortion- and contraceptive-use stigma reduction program|BEHAVIORAL: Usual Standards
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Standard Clopidogrel Versus Prasugrel Low Dose Therapy in Elderly Patients With Acute Coronary Syndrome
Status: UNKNOWN
Conditions: Coronary Artery Disease
Interventions: DRUG: Clopidogrel|DRUG: Prasugrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ride to Care - Quality of Life With Transportation for RT
Status: WITHDRAWN
Conditions: Locally Advanced Malignant Neoplasm|Metastatic Malignant Neoplasm
Interventions: OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration|PROCEDURE: Supportive Care
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Dose Finding Study To Evaluate Safety, Drug Interaction, Tumor Markers Of Axitinib In Combination With MK-3475 In Adult Patients With Previously Untreated Advanced Renal Cell Cancer
Status: COMPLETED
Conditions: Renal Cell Carcinoma
Interventions: DRUG: Axitinib|DRUG: MK-3475
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Isunakinra Alone and in Combination With a PD-1/PD-L1 Inhibitor in Patients With Solid Tumors
Status: COMPLETED
Conditions: Solid Tumor, Adult
Interventions: BIOLOGICAL: Isunakinra|BIOLOGICAL: PD-(L)1 Inhibitor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High and Low Intensity Expiratory Muscle Strength Training in Patients With Obstructive Sleep Apnea Syndrome
Status: COMPLETED
Conditions: Obstructive Sleep Apnea Syndrome
Interventions: OTHER: Expiratory muscle trainig
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Combined Oral L-ornithine-L-aspartate and Lactulose in Patients With Hepatic Encephalopathy
Status: COMPLETED
Conditions: Hepatic Encephalopathy
Interventions: DRUG: L-ornithine-L-aspartate and lactulose|DRUG: placebo and lactulose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Type 1 Hybrid Trial of Our Plan - a Brief, Couples-based HIV/STI Prevention Intervention
Status: RECRUITING
Conditions: HIV/AIDS
Interventions: BEHAVIORAL: Intervention Our Plan|BEHAVIORAL: Internation Informational Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: The Correlation and Intervention of Intestinal Flora and Frailty in the Elderly
Status: ENROLLING_BY_INVITATION
Conditions: Frailty Syndrome
Interventions: DIETARY_SUPPLEMENT: Inulin|DIETARY_SUPPLEMENT: Maltodextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: A Phase 1 Study To Evaluate The Safety And Tolerability Of Different Doses Of PF-03893787 In Healthy Adult Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: PF-03893787|DRUG: PF-03893787|DRUG: PF-03893787
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Identification of Polymorphisms Involved in the Metabolism of Propofol
Status: COMPLETED
Conditions: UGT1A1*28 Polymorphism
Interventions: DRUG: propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of Maribavir in Chinese Adults With Cytomegalovirus (CMV) Infections
Status: NOT_YET_RECRUITING
Conditions: Cytomegalovirus (CMV)
Interventions: DRUG: Maribavir
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Digital Occlusal Wafer Versus Waferless Distal Segment Repositioning for BSSO in Skeletal Mandibular Deformities
Status: UNKNOWN
Conditions: Maxillofacial Abnormalities|Jaw Abnormalities|Prognathism|Retrognathia|Micrognathism|Dentofacial Deformities|Congenital Abnormalities|Craniofacial Abnormalities
Interventions: PROCEDURE: wafer-less approach|PROCEDURE: Computer Guided orthognathic surgery using occlusal wafers
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability of Vildagliptin Versus Placebo in Patients With Type 2 Diabetes and Moderate or Severe Renal Insufficiency
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Vildagliptin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Exenatide as Monotherapy
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: exenatide|DRUG: exenatide|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Optimal Conditioning Regimen for Autologous Transplantation of Relapsing Remitting Multiple Sclerosis
Status: WITHDRAWN
Conditions: Multiple Sclerosis, Relapsing-Remitting
Interventions: OTHER: Autologous hematopoietic stem cell transplantation|DRUG: Cyclophosphamide/ATG|DRUG: Cyclophosphamide/Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of CNOP Chemotherapy in Diffuse Large B Cell Lymphoma
Status: WITHDRAWN
Conditions: Diffuse Large B Cell Lymphoma
Interventions: DRUG: Cyclophosphamide|DRUG: Vincristine|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Ritonavir-Boosted Danoprevir and RO5024048 in Different Combinations in Null Responder or Treatment-Naïve Patients With Chronic Hepatitis C and Compensated Cirrhosis
Status: COMPLETED
Conditions: Hepatitis C, Chronic
Interventions: DRUG: RO5024048|DRUG: danoprevir|DRUG: peginterferon alfa-2a [Pegasys]|DRUG: ribavirin|DRUG: ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose-dependent Effects of Blueberry Polyphenols on Endothelial Function in Healthy Individuals
Status: COMPLETED
Conditions: Endothelial Function
Interventions: DIETARY_SUPPLEMENT: Freeze-dried blueberry powder dissolved in water|DIETARY_SUPPLEMENT: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pilot Study of Antithrombin as Prophylaxis of Acute Respiratory Distress Syndrome in Patients With COVID-19
Status: COMPLETED
Conditions: Covid19|Severe Acute Respiratory Syndrome|Distress Respiratory Syndrome
Interventions: DRUG: Antithrombin + best available treatment|DRUG: Best available treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Alster Stem Cells - Intramyocardial Stem Therapy
Status: TERMINATED
Conditions: Acute Myocardial Infarction|Early Left Ventricular Dysfunction
Interventions: PROCEDURE: Percutaneous Coronary Intervention|PROCEDURE: BMNC therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Postoperative Pain After Using Different Single-File Glide Path Systems
Status: COMPLETED
Conditions: Post Operative Pain
Interventions: DEVICE: Control|DEVICE: ProGlider|DEVICE: WaveOne Gold Glider
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating 18F-FDG PET/CT With Liver SUVmax-based Criteria for Prognosis of Patients With Natural Killer/T-cell Lymphoma
Status: UNKNOWN
Conditions: Lymphoma, Extranodal NK-T-Cell
Interventions: DEVICE: 18F-FDG PET/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Vanderbilt ICU Recovery Program Pilot Trial
Status: COMPLETED
Conditions: Intensive Care Unit Syndrome|Intensive Care Neurological Disorder|Intensive Care (ICU) Myopathy|Intensive Care Psychiatric Disorder (Diagnosis)
Interventions: OTHER: VANDERBILT ICU RECOVERY PROGRAM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: An Expanded Clinical Study of Triple Therapy for Refractory Solid Tumors That Failed First-line Treatment for Recurrence and Metastasis
Status: UNKNOWN
Conditions: Advanced Cancer|Metastatic Cancer
Interventions: BIOLOGICAL: Autologous Adoptive immune cells|DEVICE: Thermotron RF-8EX|DRUG: Chemotherapy，checkpoint immunotherapy, targeted therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Ischemic Preconditioning After Aortic Clamping
Status: TERMINATED
Conditions: Vascular Surgery|Ischemia-reperfusion|Ischemia Preconditioning
Interventions: PROCEDURE: Ischemic preconditioning during aortic clamping|PROCEDURE: Procedure/Surgery: usual surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: An Open-label, Dose Escalation Multi-center Study in Patients With Advanced Cancer to Determine the Infusion Rate Effect of ASA 404 With Paclitaxel Plus Carboplatin Regimen or Docetaxel on the Pharmacokietics of Free and Total ASA404
Status: TERMINATED
Conditions: Metastatic Cancer With Impaired Renal Function|Metastatic Cancer With Normal Renal Function
Interventions: DRUG: ASA404
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: "Enhancing Surgical Safety in Developing Nations: Investigating Antibiotics' Role in Hand Surgeries."
Status: NOT_YET_RECRUITING
Conditions: Soft Tissue Injuries
Interventions: DRUG: Antibiotic|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Lung Disease and Its Affect on the Work of White Blood Cells in the Lungs
Status: RECRUITING
Conditions: Alpha-1 Antitrypsin Deficiency|AAT Deficiency|AATD|Cystic Fibrosis (CF)
Interventions: PROCEDURE: History and physical exam.|PROCEDURE: Blood draw.|PROCEDURE: Pulmonary function testing.|DRUG: Albuterol inhaler.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Bryostatin 1 and Cytarabine in Treating Patients With Relapsed Acute Myelogenous Leukemia
Status: COMPLETED
Conditions: Leukemia
Interventions: DRUG: bryostatin 1|DRUG: cytarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The GAPSID Study - How GLP-1 Analogues Prevent Steroid-Induced Diabetes
Status: NOT_YET_RECRUITING
Conditions: Steroid-Induced Diabetes|Steroid Induced Hyperglycemia
Interventions: DRUG: Semaglutide Oral Product|DRUG: Metformin Oral Tablet|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Corticosteroid Therapy for Severe Community-Acquired Pneumonia
Status: UNKNOWN
Conditions: Community Acquired Pneumonia
Interventions: DRUG: methylprednisolone|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Anti-age Dietary Supplements in Healthy Older Adults: the proBNPage Reduction Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Aging
Interventions: DIETARY_SUPPLEMENT: Coenzyme Q10|DIETARY_SUPPLEMENT: Selenium|DIETARY_SUPPLEMENT: Resveratrol|DIETARY_SUPPLEMENT: TA-65 MD|OTHER: Placebo-1|OTHER: Placebo-2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Zinc Dosing Trial - Does Dose Reduction Reduce Side Effects But Retain Efficacy in Diarrhoea Management
Status: COMPLETED
Conditions: Diarrhea
Interventions: DIETARY_SUPPLEMENT: Zinc tablets, 20 mg per day|DIETARY_SUPPLEMENT: Zinc tablets, 10 mg per day|DIETARY_SUPPLEMENT: Zinc tablets, 5 mg per day
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Ondansetron During Intramuscular Ketamine Use in Children: A Trial in Emergency Department
Status: UNKNOWN
Conditions: Sedation and Analgesia|Side Effect of Drug
Interventions: DRUG: Ondansetron
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ascorbic Acid to Prevent Postreperfusion Syndrome in Liver Transplantation
Status: RECRUITING
Conditions: Liver Transplantation|Postreperfusion Syndrome|Ascorbic Acid
Interventions: DRUG: Ascorbic acid|DRUG: 0.9% Saline solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Clinical Outcomes in Cataract Surgery With OMNI Canaloplasty vs Cataract Surgery With OMNI Canaloplasty and Hydrus Stent
Status: RECRUITING
Conditions: Glaucoma, Open-Angle
Interventions: DEVICE: OMNI canaloplasty|DEVICE: Hydrus microstent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ventilation During Cardiopulmonary Bypass
Status: COMPLETED
Conditions: Lung Injury|Postoperative Complications|Pulmonary Collapse
Interventions: OTHER: ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Optimizing Induction Chemotherapy Regimens for ND Elderly AML Patients Who Are Eligible for Intense Chemotherapy
Status: RECRUITING
Conditions: Acute Myeloid Leukemia
Interventions: OTHER: Different induction chemotherapy regimens
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nab-paclitaxel Plus Carboplatin Versus Nab-paclitaxel Plus Capecitabine in the Treatment of Advanced Triple-negative Breast Cancer
Status: UNKNOWN
Conditions: Triple Negative Breast Cancer|Nab-paclitaxel
Interventions: DRUG: Nab-paclitaxel + Carboplatin|DRUG: Nab-paclitaxel + Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sleep Quality, Daytime Sleepiness and Insomnia in Patients With Endometriosis: a Case-control Study.
Status: COMPLETED
Conditions: Endometriosis|Sleep
Interventions: OTHER: Pittsburgh Sleep Quality Index.|OTHER: Epworth sleepiness scale.|OTHER: Insomnia Severity Index.|OTHER: The Endometriosis Health Profile.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Metadoxine on Oxidative Stress in Non-alcoholic Hepatic Steatosis
Status: UNKNOWN
Conditions: NAFLD|Pre-diabetes
Interventions: DRUG: Metadoxine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transcutaneous Electrical Muscle Stimulation In Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DEVICE: Transcutaneous electrical muscle stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study With Clinical Endpoint Comparing Brinzolamide 1% Ophthalmic Suspension to Azopt® 1% Ophthalmic Suspension In the Treatment of Chronic Open Angle Glaucoma or Ocular Hypertension in Both Eyes
Status: COMPLETED
Conditions: Glaucoma
Interventions: DRUG: Test-Brinzolamide 1% Ophthalmic suspension|DRUG: Reference-Brinzolamide 1% Ophthalmic suspension
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Phase 3 Study of Tadalafil Once-Daily in Asian Men With Benign Prostatic Hyperplasia (BPH)
Status: COMPLETED
Conditions: Benign Prostatic Hyperplasia
Interventions: DRUG: Tadalafil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vaginal Uphold Hysteropexy and Laparoscopic Sacral Hysteropexy for the Treatment of Uterovaginal Pelvic Organ Prolapse
Status: COMPLETED
Conditions: Pelvic Organ Prolapse
Interventions: DEVICE: Laparoscopic sacral hysteropexy|DEVICE: Vaginal mesh hysteropexy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Efficacy Study of GEN1046 as a Single Agent or in Combination With Pembrolizumab for Treatment of Recurrent (Non-small Cell) Lung Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Non Small Cell Lung Cancer Metastatic
Interventions: BIOLOGICAL: Acasunlimab|BIOLOGICAL: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ESP Catheter Vs Single Shot ESP for Open Heart Surgery in Infants
Status: COMPLETED
Conditions: Opioid Use|Pain, Postoperative|Quality of Life
Interventions: DRUG: Continuous infusion of ropivacain in ESP catheter|DRUG: Continuous infusion of Iso Saline in ESP catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Early Versus Delayed Surgery for Gallstone Pancreatitis
Status: COMPLETED
Conditions: Gallstone Pancreatitis
Interventions: PROCEDURE: Laparoscopic cholecystectomy within 48 hours of admission|PROCEDURE: Laparoscopic cholecystectomy after resolution of abdominal pain and laboratory values
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Oncoxin Plus Surafineb in Hepatocellular Carcinoma
Status: UNKNOWN
Conditions: Quality of Life
Interventions: DIETARY_SUPPLEMENT: Oncoxin|DRUG: Suranix
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Predictive Model for Oropharyngeal Dysphagia in Non-hospitalized Older Patients
Status: NOT_YET_RECRUITING
Conditions: Deglutition Disorders|Otorhinolaryngologic Diseases|Oropharyngeal Dysphagia
Interventions: OTHER: No intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Analgesic Efficacy of Ropivacaine Alone or in Combination With Adjuvants on Post-operative Analgesia Following Video-Assisted Thoracoscopic Surgery.
Status: COMPLETED
Conditions: Postoperative Analgesia
Interventions: DRUG: Ropivacaine + Ketamine|DRUG: Ropivacaine + Tramadol|DRUG: Ropivacaine + Midazolam|DRUG: Ropivacaine + Dexmedetomidine|DRUG: Ropivacaine + Dexamethasone|DRUG: Ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cognitive Resilience Intervention as a Recovery Therapy for Mental Health
Status: NOT_YET_RECRUITING
Conditions: Reduction in Mental Health and Suicide Are the Focus of Interest|Four Assessment Time Points Would be Used to Monitor Participants Through a Laid Down Conditions
Interventions: BEHAVIORAL: Cognitive Resilience Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ANRS HB 05 Multicenter Study Evaluating Efficacy and Safety of Clevudine Monotherapy Versus Tenofovir Monotherapy Versus Combination Therapy of Clevudine and Tenofovir for 96 Weeks in HBeAg Negative Patients With Chronic Hepatitis B, naïve to Anti-VHB Therapy
Status: TERMINATED
Conditions: HBe Negative Chronic Hepatitis B|Hepatitis B Viral Infection
Interventions: DRUG: CLEVUDINE + TENOFOVIR PLACEBO|DRUG: CLEVUDINE IN ASSOCIATION TENOFOVIR|DRUG: TENOFOVIR + CLEVUDINE PLACEBO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Melatonin on Postoperative Delirium in Elderly ICU Patients
Status: TERMINATED
Conditions: Delirium
Interventions: DIETARY_SUPPLEMENT: Melatonin|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Pomalidomide in Anal Cancer Precursors
Status: UNKNOWN
Conditions: High Grade Squamous Intra-epithelial Lesion (HSIL)
Interventions: DRUG: Pomalidomide 2 MG Oral Capsule [Pomalyst]
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clocks in Sync - Circadian Rhythm and Bipolar Mania
Status: NOT_YET_RECRUITING
Conditions: Bipolar Disorder|Mania
Interventions: DEVICE: Blue-blocking glasses|BEHAVIORAL: Time-restricted eating|DEVICE: Lightly tinted glasses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intestines and Liver Contribution to Fasting Postprandial Hypertriglyceridemia
Status: COMPLETED
Conditions: Hypertriglyceridemia|Metabolic Syndrome
Interventions: OTHER: Postprandial test
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study to Evaluate the Immunogenicity and Safety of 2 Formulations of GlaxoSmithKline (GSK) Biologicals' GSK1247446A Low Dose Influenza Vaccine Candidate
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Fluarix™|BIOLOGICAL: GSK1247446A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Study Called VICTORIA to Learn More About How Well Larotrectinib Works in Adults With TRK Fusion-positive Cancer by Comparing Larotrectinib Data From Clinical Studies With Data of Other Treatments From Actual Practice
Status: COMPLETED
Conditions: Solid Tumors Harboring NTRK Fusion
Interventions: DRUG: Larotrectinib(Vitrakvi, BAY2757556)|DRUG: Data on other treatments
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Stem Cell Heart Injections During Laser Revascularization Surgery for Treatment of Chronic Ischemic Heart Disease
Status: COMPLETED
Conditions: Chronic Ischemic Heart Disease
Interventions: DRUG: Bone Marrow Derived Autologous CD133+ Selected Cell Product
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Apatinib in Combination With Stereotactic Body Radiation Therapy (SBRT) Treatment for Symptomatic Metastatic Prostate Cancer
Status: COMPLETED
Conditions: Quality of Life
Interventions: DRUG: Apatinib|RADIATION: SBRT to symptomatic bony metastatic bony site(s)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Sedentary Behavior Reduction in Pregnancy Intervention Study
Status: COMPLETED
Conditions: Pregnancy Complications|Sedentary Behavior
Interventions: BEHAVIORAL: Sedentary Behavior Reduction|BEHAVIORAL: Information on Physical Activity Recommendations during Pregnancy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Safety, Tolerability, and Preliminary Efficacy of CBL-514 Injection for Reducing Convexity or Fullness of Abdominal Subcutaneous Fat
Status: COMPLETED
Conditions: Subcutaneous Fat
Interventions: DRUG: CBL-514
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Biomarkers of Neurodegeneration in Parkinsonian Syndromes
Status: NOT_YET_RECRUITING
Conditions: Parkinson Disease|Progressive Supranuclear Palsy
Interventions: PROCEDURE: 7 Tesla MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Low-dose Arginine-vasopressin Supplementation on Post-transplant Acute Kidney Injury After Liver Transplantation (AVENIR Trial)
Status: NOT_YET_RECRUITING
Conditions: Acute Kidney Injury Post Liver Transplantation
Interventions: DRUG: Arginine vasopressin|DRUG: Norepinephrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of an Antioxidants Mix on Cognitive Performance and Well Being: The Bacopa, Licopene, Astaxantina, Vitamin B12
Status: COMPLETED
Conditions: Cognitive Dysfunction
Interventions: DIETARY_SUPPLEMENT: A mix of bioactive natural compounds|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Patients Who Underwent Sleeve Gastrectomy With Jejunoileal Anastomosis for the Treatment of Morbid Obesity
Status: COMPLETED
Conditions: Sleeve Gastrectomy With Jejunoileal Anastomosis
Interventions: PROCEDURE: Sleeve gastrectomy with jejunoileal anastomosis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Effectiveness Study of RF Ablation of Uterine Fibroids to Reduce Menstrual Bleeding: the Fibroid Ablation Study
Status: WITHDRAWN
Conditions: Leiomyoma|Uterine Fibroids|Menorrhagia
Interventions: DEVICE: VizAblate Intrauterine Ultrasound-Guided RF Ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigating the Safety and Efficacy of Rituximab and Pembrolizumab in Relapsed/Refractory Waldenström's Macroglobulinaemia
Status: COMPLETED
Conditions: Waldenstrom Macroglobulinemia
Interventions: DRUG: Pembrolizumab|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparison Between Two Video Laryngoscopes,in Successfully Intubating Pediatric Mannequins w/wo Difficult Airways
Status: COMPLETED
Conditions: Intubation; Difficult
Interventions: DEVICE: Miller blade|DEVICE: Truview PCD|DEVICE: Glidescope Cobolt
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Effectiveness and Safety of High Frequency Electrotherapy in Patients With Meibomian Gland Dysfunction
Status: UNKNOWN
Conditions: Meibomian Gland Dysfunction
Interventions: DEVICE: Rexon-eye
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dinoprostone Vaginal Insert Versus Double Balloon Catheter for Preinduction Cervical Ripening
Status: UNKNOWN
Conditions: Labor Induction
Interventions: DEVICE: Cook Double Balloon Catheter|DRUG: Dinoprostone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Randomized Placebo-controlled Analysis of Superior Laryngeal Nerve Block for Neurogenic Cough
Status: RECRUITING
Conditions: Cough|Nerve Block
Interventions: DRUG: Superior laryngeal nerve block - Intervention (Bupivacaine and triamcinolone acetonide suspension)|DRUG: Superior laryngeal nerve block - Placebo (saline)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study of the Microbiological Profile of Stool in Patients With Anorexia Nervosa
Status: WITHDRAWN
Conditions: Anorexia Nervosa|Eating Disorder
Interventions: BIOLOGICAL: blood sampling|OTHER: stool sampling|OTHER: urine sampling|DIAGNOSTIC_TEST: neuropsychological tests
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Corticospinal and Motor Behavior Responses After Physical Therapy Intervention in Patients With Chronic Low Back Pain.
Status: RECRUITING
Conditions: Low Back Pain
Interventions: DEVICE: Active-tDCS priming MCE|DEVICE: Sham-tDCS priming MCE|DEVICE: NMES priming MCE|OTHER: Conventional physical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT