pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Levofloxacin For The Management Of Patients With Abnormal Prostate Specific Antigen (PSA)
Status: COMPLETED
Conditions: Prostatic Hyperplasia|Prostatitis
Interventions: DRUG: Levofloxacin oral tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effect of 12 Weeks of Resistive Exercises Versus Aerobic Exercises in Overweight Hypertensive Postmenopausal Women
Status: COMPLETED
Conditions: Exercise
Interventions: DEVICE: resistive exercise|DEVICE: aerobic exercise in form of treadmill walking
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Anhedonia, Development, and Emotions: Phenotyping and Therapeutics
Status: ACTIVE_NOT_RECRUITING
Conditions: Depression|Anhedonia
Interventions: DEVICE: Continuous theta burst stimulation (cTBS)|BEHAVIORAL: Positive Affect Training|DRUG: Ketamine Injectable Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Use of a Prehospital Ultrasound System and Standard Prehospital Care in Thoracoabdominal Trauma
Status: COMPLETED
Conditions: Thoracoabdominal Trauma|Focused Assessment With Sonography for Trauma (FAST)|NanoMaxx Ultrasound System (SonoSite)|RP-Xpress (InTouch Technologies)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Healthy Patterns Sleep Study
Status: COMPLETED
Conditions: Dementia|Alzheimer Disease|Circadian Rhythm Disorders|Circadian Rhythm Sleep Disorder|Insomnia|Hypersomnia|Cognitive Impairment|Cognitive Decline|Mild Cognitive Impairment|Frontotemporal Dementia|Neurocognitive Disorders|Vascular Dementia|Sleep Disorder|Memory Impairment
Interventions: BEHAVIORAL: Attention-Control Condition|BEHAVIORAL: Timed Activity Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Impact of Intravenous Bendavia™ on Endothelial Reactivity Dysfunction in Cigarette Smoking
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Bendavia|DRUG: Sterile saline (0.9%)|OTHER: Cigarette smoking
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Tizanidine on Postoperative Urinary Retention After Sacrospinous Suspension
Status: NOT_YET_RECRUITING
Conditions: Postoperative Urinary Retention|Sacrospinous Vaginal Vault Suspension|Reconstructive Pelvic Surgery
Interventions: DRUG: Tizanidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Phase III Randomized, Double-Blind Study of Dexamethasone Vs Dexamethasone/Methylprednisolone Vs Placebo for Bronchopulmonary Dysplasia
Status: COMPLETED
Conditions: Bronchopulmonary Dysplasia
Interventions: DRUG: dexamethasone|DRUG: methylprednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: An Efficacy and Safety Study of LYC-30937-EC in Subjects With Moderate Chronic Plaque-type Psoriasis
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: Drug: LYC-30937-EC|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Transcutaneous Vagus Nerve Stimulation (tVNS) for Improved Recovery After Exertion.
Status: NOT_YET_RECRUITING
Conditions: Post-COVID-19 Syndrome
Interventions: DEVICE: transcutaneous vagus nerve stimulation|BEHAVIORAL: Monitoring|DEVICE: cardiowatch bracelet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Heart Failure Optimization at Home to Improve Outcomes (Hozho): A Pragmatic in Navajo Nation
Status: COMPLETED
Conditions: Heart Failure
Interventions: BEHAVIORAL: EHR-based GDMT Optimization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Screening for Hepatitis C Using a Rapid Diagnostic Orientation Test (TROD) in Patients Over 50 Years Old in the Digestive Endoscopy Department of the Europeen Hospital Marseille
Status: UNKNOWN
Conditions: Hepatitis C
Interventions: DIAGNOSTIC_TEST: Rapid diagnostic orientation test (TROD) for Hepatitis C
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of De-epithelized Connective Tissue Grafts and Modified Combined Approach for Connective Tissue Grafts
Status: RECRUITING
Conditions: Gingival Recession
Interventions: PROCEDURE: modified combined approach|PROCEDURE: de-epithelized gingival graft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Self-Assembling Peptides on the Progression of Non-Cavitated Proximal Caries
Status: COMPLETED
Conditions: Proximal Caries
Interventions: DEVICE: Curodont™ Repair|DEVICE: MI Varnish™|DEVICE: Profluorid® Varnish
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical, Inflammatory and Functional Evaluation of a Population of Severe and Obese Asthmatics: Follow up
Status: UNKNOWN
Conditions: Severe Asthma|Obesity
Interventions: PROCEDURE: Bariatric
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of Alpha Lipoid Acid and Vitamin B Preparation on Diabetic Polyneuropathy in Type 2 Diabetes Mellitus Patient
Status: RECRUITING
Conditions: Diabetic Polyneuropathy
Interventions: DRUG: Alpha-Lipoic Acid/Vitamin/Mineral Supplement PolyMVA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Long-term Use of CCB and Breast Cancer Risk
Status: ACTIVE_NOT_RECRUITING
Conditions: Hypertension,Essential|Breast Cancer
Interventions: DRUG: Calcium channel blocker|DRUG: Beta blocker|DRUG: Diuretic|DRUG: RAS|DRUG: Other AHT|DRUG: None AHT
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Safety and Efficacy Evaluation of BLI801 Laxative in Constipated Adults
Status: COMPLETED
Conditions: Constipation
Interventions: DRUG: BLI801 laxative - low dose|DRUG: BLI801 laxative - high dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: MRX-800: A Long-Term Safety Study of Maralixibat in the Treatment of Cholestatic Liver Disease in Subjects Who Previously Participated in a Maralixibat Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Cholestatic Liver Disease
Interventions: DRUG: Maralixibat
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of CRT on the Frank Starling Mechanism
Status: RECRUITING
Conditions: Pacemaker|Heartfailure
Interventions: OTHER: Test Of The Frank Starling Mechanism - Adjustment Of Av Delay And Measurement Of Pre-load -Control|OTHER: Other: Test Of The Frank Starling Mechanism - Adjustment Of Av Delay And Measurement Of Pre-load -CRT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Estimation Of Effect Of Ketoconazole On Pharmacokinetics Of Crizotinib In Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: crizotinib|DRUG: ketoconazole|DRUG: crizotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Erector Spinae Plane Block Versus Transversus Abdominis Plane Block in Abdominoplasty Surgery
Status: UNKNOWN
Conditions: Abdominoplasty
Interventions: PROCEDURE: Erector spinea plane block group|PROCEDURE: Transversus abdominis plane block|PROCEDURE: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Coronary Artery Bypass Grafting Strategies for the Anterolateral Territory: a Prospective Randomized Clinical Trial
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: PROCEDURE: LIMA to SVG Bridge Technique|PROCEDURE: Conventional CABG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: IMPULSE: A Safety and Feasibility Study of the IOWA Approach Endocardial Ablation System to Treat Atrial Fibrillation
Status: COMPLETED
Conditions: Paroxysmal Atrial Fibrillation
Interventions: DEVICE: IOWA Approach Endocardial Ablation System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Musculoskeletal Pain, Motor Control, Risk of Falls and Virtual Reality
Status: NOT_YET_RECRUITING
Conditions: Musculoskeletal Pain|Task Performance and Analysis|Accidental Falls|Virtual Reality
Interventions: DEVICE: Virtual Reality
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Coronary Atherectomy System in Patients With Coronary Calcification (CORECT)
Status: ENROLLING_BY_INVITATION
Conditions: Calcification of Coronary Artery
Interventions: DEVICE: Coronary atherectomy system of Shanghai MicroPort Rhythm|DEVICE: Rotablator Rotational Atherectomy System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study of NST-6179 in Healthy Subjects
Status: COMPLETED
Conditions: Short Bowel Syndrome|Parenteral Nutrition Associated Liver Disease
Interventions: DRUG: NST 6179|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating Safety and Biomarkers Using DK210 (EGFR) for Locally Advanced or Metastatic EGFR+ Tumors
Status: RECRUITING
Conditions: Cancer|Solid Tumor|Colorectal Cancer|Pancreas Cancer|Non Small Cell Lung Cancer|Head and Neck Cancer|Gynecologic Cancer|Skin Cancer|Kidney Cancer
Interventions: BIOLOGICAL: DK210 (EGFR)|RADIATION: Radiation therapy|BIOLOGICAL: Immune checkpoint blockers|DRUG: Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PROSTVAC®-VF/TRICOM™ Vaccine for the Treatment of Metastatic Prostate Cancer After Failing Hormone Therapy
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: BIOLOGICAL: PROSTVAC®-VF/TRICOM™
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Hypofraction Radiotherapy for Locally Advanced Non-small Cell Lung Cancer
Status: RECRUITING
Conditions: Toxicity Due to Radiotherapy|Non-small Cell Lung Cancer
Interventions: RADIATION: High-dose fractionated radiotherapy|RADIATION: Low-dose fractionated radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Interest of Continuous Ropivacaine Administration Through an Elastomeric Pump (Pain Buster) for the Surgery of Latissimus Dorsi and Serratus Micro Anastomotic Flaps
Status: TERMINATED
Conditions: Post Operative Analgesia
Interventions: DRUG: Naropeine (Ropivacaine)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Node and Atrial Fibrillation Ablation for Persistent Atrial Fibrillation
Status: UNKNOWN
Conditions: Persistent Atrial Fibrillation
Interventions: PROCEDURE: AF ablation and AV node ablation|PROCEDURE: AV node ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Central Sensitization, Neuropathic Pain, Sleep Quality and Daily Life Activities in Behcet's Disease
Status: COMPLETED
Conditions: Behcet's Disease|Central Sensitisation
Interventions: DIAGNOSTIC_TEST: Central sensitisation|DIAGNOSTIC_TEST: Neuropathic pain|OTHER: Sleep disturbance|OTHER: Quality of life
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Evaluate Multiple Oral Doses of Luvadaxistat in Adults With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Luvadaxistat|DRUG: Matching Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Remifentanil Only vs. Midazolam and Meperidine During Elective Colonoscopy
Status: COMPLETED
Conditions: Diagnostic Colonoscopy Screening
Interventions: DRUG: Remifentanil|DRUG: Midazolam|DRUG: Meperidine|DRUG: placebo (for remifentanil)|DRUG: placebo (for midazolam)|DRUG: placebo (for meperidine)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of GC1008 in Patients With Idiopathic Pulmonary Fibrosis (IPF)
Status: COMPLETED
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: BIOLOGICAL: GC1008|BIOLOGICAL: GC1008|BIOLOGICAL: GC1008|BIOLOGICAL: GC1008|BIOLOGICAL: GC1008
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neurostimulation and Cognitive Intervention in Alzheimer's Disease
Status: UNKNOWN
Conditions: Alzheimer's Disease
Interventions: DEVICE: active tDCS|DEVICE: sham tDCS|BEHAVIORAL: real CT|BEHAVIORAL: placebo CT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Using Stable Isotope Techniques to Monitor and Assess the Vitamin A Status of Children Susceptible to Infection
Status: COMPLETED
Conditions: Vitamin A Deficiency
Interventions: DIETARY_SUPPLEMENT: Mega-dose of vitamin A supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect of Flipped Classroom and Peer-Supported Education
Status: ACTIVE_NOT_RECRUITING
Conditions: Stoma Colostomy|Self Efficacy
Interventions: OTHER: Stoma care education with flipped classroom|OTHER: Stoma care education with peer-supported education model
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: A Study to Test the Long-term Use of Oral Lacosamide in Pediatric Study Participants Who Completed NCT01964560 (EP0034) or NCT00938912 (SP848) and Received Lacosamide Treatment
Status: ACTIVE_NOT_RECRUITING
Conditions: Epilepsy
Interventions: DRUG: Lacosamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Single Administration Intravenous Treatment for Influenza
Status: TERMINATED
Conditions: Influenza
Interventions: DRUG: AVI-7100|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Edoxaban Compared to Standard Care After Heart Valve Replacement Using a Catheter in Patients With Atrial Fibrillation (ENVISAGE-TAVI AF)
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DRUG: Edoxaban-based Regimen|DRUG: VKA-based Regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy Drug Sensitivity Microculture (MiCK) Assay for Apoptosis
Status: COMPLETED
Conditions: Breast Neoplasms|Lung Neoplasms|Ovarian Neoplasms|Sarcoma, Soft Tissue
Interventions: OTHER: Laboratory Assay|OTHER: Mick Assay
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Smartphone Delivered In-home Cardiopulmonary Rehabilitation
Status: ACTIVE_NOT_RECRUITING
Conditions: Cardiovascular Disease|Coronary Artery Disease
Interventions: BEHAVIORAL: MULTIFIT Cardiac Rehabilitation|BEHAVIORAL: Movn Pulmonary Rehabilitation|BEHAVIORAL: Standard of Care Cardiac Rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Immunogenicity of Two Doses of DCVC H1 HA mRNA-LNP in Healthy Adults
Status: RECRUITING
Conditions: Influenza
Interventions: BIOLOGICAL: DCVC H1 HA mRNA vaccine|BIOLOGICAL: Quadrivalent Recombinant Seasonal Influenza Vaccine|OTHER: Sodium Chloride, 0.9%
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Cascade PRFM Study: The Evaluation of Cascade Platelet-Rich Fibrin Matrix (PRFM) on Rotator Cuff Healing
Status: WITHDRAWN
Conditions: Rotator Cuff|Tendon Injuries
Interventions: PROCEDURE: Placement of Platelet Rich Fibrin Matrix During Arthroscopic Rotator Cuff Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Effect of Preoperative Aspirin in Patients Undergoing Off-pump Coronary Artery Bypass Grafting
Status: UNKNOWN
Conditions: Coronary Artery Disease|Aspirin
Interventions: DRUG: Aspirin|DRUG: vitamin C
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Peptide-based Glioma Vaccine IMA950 in Patients With Glioblastoma
Status: TERMINATED
Conditions: Glioblastoma
Interventions: DRUG: Cyclophosphamide|BIOLOGICAL: IMA950 plus GM-CSF|BIOLOGICAL: IMA950|DRUG: Imiquimod
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Circulating Tumor DNA Guided Surveillance Strategy of Stage III Colorectal Cancer: an Open, Prospective, Randomized Controlled Cohort Study
Status: UNKNOWN
Conditions: Stage III Colorectal Cancer|Circulating Tumor DNA
Interventions: DIAGNOSTIC_TEST: ctDNA dynamic monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: CryoSpray Ablation(tm)in Malignant Airway Disease to Determine Safety, and Tissue Effect in the Lung (ICE the MAD)
Status: TERMINATED
Conditions: Lung Cancer|Mesothelioma
Interventions: DEVICE: CryoSpray Ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Psychoeducation Program for Families Caregivers of Schizophrenic Patients : Randomized Study in Two Arms
Status: UNKNOWN
Conditions: Schizophrenia|Mental Disorder|Educational Problems|Family Relations|Relapse|Medication Adherence|Psychiatric Disorder|Psychiatric Hospitalization
Interventions: BEHAVIORAL: Psychoeducation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Non Invasive Cardiac Output Monitoring to Guide Goal Directed Fluid Therapy in High Risk Patients Undergoing Urgent Surgical Repair of Proximal Femoral Fractures
Status: COMPLETED
Conditions: Hip Fractures
Interventions: OTHER: Fluid optimisation|DRUG: Optimisation of blood pressure|DEVICE: Application of clearsight monitor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prone Partial Breast Irradiation (PBI): a Prospective Randomized Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer
Interventions: RADIATION: PBI Radiotherapy 6 Gy|RADIATION: PBI Radiotherapy 8 Gy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I Study of Bavituximab, Capecitabine, and Radiation for the Treatment of Rectal Adenocarcinoma
Status: COMPLETED
Conditions: Rectal Adenocarcinoma
Interventions: RADIATION: Radiation|DRUG: Bavituximab|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Technology Based Psychosocial Intervention for Symptom Management and HRQOL in Men Living With Advanced Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: BEHAVIORAL: Technology based cognitive behavioral stress management|BEHAVIORAL: Technology based health promotion group-based attention matched control condition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Terlipressin Administration in Patients Undergoing Major Liver Resection
Status: TERMINATED
Conditions: Liver Resection|Liver Failure
Interventions: DRUG: Terlipressin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety of Different rMenB Plus MenACWY Formulations in Adolescents
Status: COMPLETED
Conditions: Meningococcal Disease|Meningococcal Meningitis
Interventions: BIOLOGICAL: Meningococcal Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy, Safety and Tolerability of AEB071 in Patients With Active, Moderate to Severe Ulcerative Colitis
Status: COMPLETED
Conditions: Ulcerative Colitis
Interventions: DRUG: AEB071|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Multispectral Optoacoustic Tomography in Patients With Cystic Fibrosis
Status: RECRUITING
Conditions: Cystic Fibrosis|Liver Fibrosis|Gastrointestinal Transport Disorder|Dios
Interventions: DIAGNOSTIC_TEST: Acoustic Radiation Forced Impulse Imaging|DIAGNOSTIC_TEST: Multispectral Optoacoustic Tomography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Vaginal Hysterectomy vs Supracervical Hysterectomy at the Time of Sacrocolpopexy
Status: RECRUITING
Conditions: Vaginal Hysterectomy|Laparoscopic Supracervical Hysterectomy
Interventions: OTHER: Laparoscopic supracervical hysterectomy|OTHER: Vaginal hysterectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Percutaneous Trigger Finger Release Concomitant Steroid Injection Versus Percutaneous Trigger Finger Release Alone
Status: COMPLETED
Conditions: Trigger Finger|Percutaneous A1 Pulley Release|Steroid Injection|Postoperative Pain
Interventions: PROCEDURE: percutaneous A1 pulley release|DRUG: Triamcinolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: OXN PR Compared to OXY PR in Subjects With Postoperative Pain After Knee Arthroplasty
Status: COMPLETED
Conditions: Post Operative Pain
Interventions: DRUG: Oxycodone/Naloxone PR 20/10mg or 10/5mg tablets|DRUG: Oxycodone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PHOTOFINISH: a Clinical Study To Evaluate The Efficacy And Safety Of the System VULNOFAST® Plus/VULNOLIGHT® In Addition To The Usual Care (UC) Vs UC Alone For The Treatment Of Infected Diabetic Foot Ulcers
Status: RECRUITING
Conditions: Diabetic Foot Infection
Interventions: OTHER: Usual Care alone|DEVICE: System VULNOFAST® plus / VULNOLIGHT® in addition to Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TP0502-Pharmaco-Scintigraphic-Study and Amendment
Status: COMPLETED
Conditions: Ulcerative Colitis
Interventions: DRUG: TP05 Coating D|DRUG: TP05 Coating E|DRUG: TP05 Coating H
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Analgesic Induces Similar Upper and Lower Body Pain Pressure Threshold Increases
Status: COMPLETED
Conditions: Pain, Acute|Muscle Soreness|Tendon Injuries
Interventions: COMBINATION_PRODUCT: Menthol based topical analgesic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Pilot Study Using Short-Term Cultured Anti-Tumor Autologous Lymphocytes
Status: TERMINATED
Conditions: Metastatic Melanoma
Interventions: DRUG: Tumor Infiltrating Lymphocytes|DRUG: Nivolumab and Ipilimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chidamide in Combination With ART for Reactivation of the Latent HIV-1 Reservoir
Status: UNKNOWN
Conditions: Chronic HIV Infections
Interventions: DRUG: ART plus Chidamide|DRUG: ART plus Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 2, Double-blind Study to Evaluate Intranasal Trivalent Influenza Virus Vaccine in Healthy Adult
Status: COMPLETED
Conditions: Influenza Infection
Interventions: BIOLOGICAL: AD07010|BIOLOGICAL: Inactivated trivalent influenza vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Autologous Transplant Using Dose-Escalated Total Body Irradiation & Cyclophosphamide & Palifermin for NHL
Status: COMPLETED
Conditions: Relapsed Non Hodgkin Lymphoma|Refractory Non-Hodgkin Lymphoma
Interventions: RADIATION: Total body irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Orally Fludarabine, Adriamycin and Dexamethasone (FAD) in Newly Diagnosed Peripheral T-cell Lymphomas (PTCL)
Status: UNKNOWN
Conditions: T-Cell Lymphomas|Chemotherapy
Interventions: DRUG: FAD
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dynamics of Androgen Receptor Genomics and Transcriptomics After Neoadjuvant Androgen Ablation
Status: COMPLETED
Conditions: Prostate Cancer|DNA|Androgen Receptor Abnormal
Interventions: DRUG: Enzalutamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neurofeedback Impact on Veterans With mTBI
Status: ACTIVE_NOT_RECRUITING
Conditions: Concussion|mTBI|Post-Concussive Symptoms|Chronic Headache|Chronic Insomnia|Chronic Attention Disorder
Interventions: PROCEDURE: Neurofeedback (NFB)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Evaluate the Efficacy of Probiotics Toothpastes in Improvement of Gingivitis and Prevention of Periodontal Diseases Via Modulating the Oral Microbiota
Status: COMPLETED
Conditions: Gingivitis
Interventions: OTHER: Placebo|OTHER: GMNL-143 Probiotic Toothpastes|OTHER: GMNL-464 Probiotic Toothpastes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy, Safety, and Tolerability of ACZ885 in Patients With Muckle-Wells Syndrome
Status: COMPLETED
Conditions: Muckle Wells Syndrome
Interventions: DRUG: ACZ885|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Partially Hydrolyzed Formula in Cow's Milk Protein Allergy After 6 Months of Elimination
Status: RECRUITING
Conditions: Cow's Milk Protein Allergy
Interventions: DIETARY_SUPPLEMENT: Partially hydrolyzed formula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Feasibility Study of Image Guided Noninvasive Single Fraction Stereotactic Radiosurgery for the Treatment of Brain Metastases
Status: COMPLETED
Conditions: Metastatic Brain Cancer
Interventions: OTHER: Fabrication of thermoplastic face (The Orfit thermoplastic face mask system is routinely used for the treatment of brain and head)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Interest of a Nursing Consultation in the Empowerment of the Patient With Rheumatoid Arthritis in the Management of His Subcutaneous Biotherapy
Status: ACTIVE_NOT_RECRUITING
Conditions: Biotherapies|Rheumatology|Rheumatoid Arthritis
Interventions: DEVICE: nursing consultation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Icotinib as Consolidation Therapy After Chemoradiotherapy in EGFR-Mutant Stage IIIA-IIIB Non-small Cell Lung Cancer
Status: UNKNOWN
Conditions: EGFR Gene Mutation|Non Small Cell Lung Cancer Stage IIIA|Non Small Cell Lung Cancer Stage IIIB
Interventions: DRUG: Icotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: S-Equol in Alzheimer's Disease 2 Trial
Status: COMPLETED
Conditions: Alzheimer Disease
Interventions: DRUG: S-equol and Placebo|DRUG: Placebo and S-equol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Stellate Ganglion Block on New Atrial Fibrillation After Coronary Artery Bypass Grafting
Status: RECRUITING
Conditions: Stellate Ganglion Block
Interventions: PROCEDURE: Stellate nerve block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effects of Rotator Interval Hydro-dissection in Primary Adhesive Capsulitis.
Status: NOT_YET_RECRUITING
Conditions: Adhesive Capsulitis of Shoulder
Interventions: DRUG: Rotator interval hydro-dissection with dextrose 5%|DRUG: Rotator interval hydro-dissection with corticosteroid solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Controlled Trial of Genomically Directed Therapy in Patients With Triple Negative Breast Cancer
Status: COMPLETED
Conditions: Malignant Neoplasm of Breast|Breast Cancer
Interventions: DRUG: Genomically Directed Monotherapy|OTHER: Observation/Standard Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RESTORE: REducing Future fractureS and Improving ouTcOmes of fRagility fracturE
Status: NOT_YET_RECRUITING
Conditions: Osteoporosis|Osteoporotic Fractures
Interventions: BEHAVIORAL: Augmented-Fracture Liaison Service Arm|BEHAVIORAL: Enhanced Usual Care Arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Ultrasound Guided Axillary Brachial Plexus Block Versus Supraclavicular Block in Emergency Crushed Hand Patients
Status: COMPLETED
Conditions: the Study Focuses on Comparing Between Supraclavicular and Axillary Blocks
Interventions: PROCEDURE: brachial plexus block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: |Primary Purpose: OTHER
Clinical trial: Fitmore Versus CLS Stem in Total Hip Arthroplasty. Bilateral One-stage Operations
Status: ACTIVE_NOT_RECRUITING
Conditions: Primary Hip Osteoarthritis|Secondary Hip Osteoarthritis Due to Idiopathic Femoral Head Necrosis, Childhood or Inflammatory Disease|Bilateral Hip Disease|Surgical Treatment
Interventions: DEVICE: Total hip arthroplasty (Fitmore or CLS uncemented femoral stem made by Zimmer-Biomet, Warshaw, USA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combined Treatment for Tobacco and Alcohol Use
Status: WITHDRAWN
Conditions: Smoking Cessation
Interventions: BEHAVIORAL: Questionnaires|BEHAVIORAL: Motivational Relapse Prevention Counseling|BEHAVIORAL: Relapse Plus Alcohol Risk Reduction Counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of Using Computerized Education to Increase Patients' Confidence in Their Ability to Be Screened for Colon Cancer
Status: COMPLETED
Conditions: Colorectal Cancer Screening
Interventions: DEVICE: Personally-tailored educational software program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Investigation of Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Multiple Dosing of NNC0174-0833 in Subjects With Obesity or Overweight
Status: COMPLETED
Conditions: Metabolism and Nutrition Disorder|Obesity
Interventions: DRUG: NNC0174-0833|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Ketamine and Guanfacine on Working Memory in Healthy Subjects
Status: COMPLETED
Conditions: NMDA Receptor Function
Interventions: DRUG: Guanfacine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study to Estimate the Pharmacokinetics, Bioavailability and Effect of Food on Single Dose Modified-release Lersivirine 500 mg in Healthy Subjects
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: Lersivirine Immediate-Release (fasted)|DRUG: Lersivirine Modified-Release #1 (fasted)|DRUG: Lersivirine Modified-Release #2 (fasted)|DRUG: Lersivirine Modified-Release #3 (fasted)|DRUG: Lersivirine Modified-Release (fed)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Dietary Biomarkers Intervention Core
Status: RECRUITING
Conditions: Biological Markers|Diet, Healthy|Metabolomics|Nutrition, Healthy
Interventions: OTHER: Pharmacokinetic (PK)- Controlled Feeding Diet|OTHER: Dose Response (DR)- Controlled Feeding Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Interventional Endoscopy Database for Pancreatico-biliary, Gastrointestinal and Esophageal Disorders
Status: UNKNOWN
Conditions: Ampullary Cancer|Duodenal Cancer|Bile Duct Cancer|Bile Duct Disorders|Gallstones|Obstructive Jaundice|Pancreatic Disorders (Noncancerous)|Colorectal Cancer|Esophageal Cancer|Barrett's Esophagus|Gastric Malignancies|Pancreatic Cancer|Pediatric Gastroenterology|Cholangiocarcinoma|Pancreatic Pseudocysts|Acute and Chronic Pancreatitis|Recurrent Pancreatitis|Cholangitis|Bile Leak|Biliary Strictures|Pancreatic Divisum|Biliary and Pancreatic Stones|Choledocholithiasis
Interventions: PROCEDURE: Interventional Endoscopy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Safety and Effectiveness Trial of Spinal Cord Stimulation of the Dorsal Root Ganglion for Chronic Lower Limb Pain
Status: COMPLETED
Conditions: Chronic Lower Limb Pain
Interventions: DEVICE: AXIUM Neurostimulator System|DEVICE: Control Spinal Cord Stimulation Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: VISUPRIME® Eye Drops
Status: COMPLETED
Conditions: Macular Degeneration, Age Related|Myopic Choroidal Neovascularisation|Proliferative Diabetic Retinopathy|Diabetic Macular Edema|Macular Edema of Right Retina (Diagnosis)
Interventions: DEVICE: VISUPRIME|DEVICE: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Lungs of Normal Individuals by Lung Lavage, Brushing and Bronchial Wall Biopsy
Status: COMPLETED
Conditions: Smoking|Lung Diseases
Interventions: PROCEDURE: Bronchopulmonary Lung Lavage|PROCEDURE: Bronchial Brushing|PROCEDURE: Bronchial Wall Biopsy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Additive Effect of Endonase on Eradication Rate of Second Line Therapy for HP Infection
Status: TERMINATED
Conditions: Helicobacter Pylori Infection
Interventions: DRUG: Second-line quadruple therapy with endonase
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Low Dose Ketamine on Cardiovascular Function
Status: TERMINATED
Conditions: Healthy
Interventions: DRUG: Ketamine|DRUG: Saline (placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: HIPEC in the Treatment of Stage IIc-IV Epithelial Ovarian Cancer After CRS (HIPECOC)
Status: UNKNOWN
Conditions: Ovarian Cancer|Hyperthermic Intraperitoneal Chemotherapy
Interventions: PROCEDURE: Hyperthermic Intraperitoneal Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: IDP-023 as a Single Agent and in Combination With Antibody Therapies in Patients With Advanced Hematologic Cancers
Status: RECRUITING
Conditions: NHL|Multiple Myeloma|Blood Cancer|Refractory Non-Hodgkin Lymphoma|Relapsed Non-Hodgkin Lymphoma|Refractory Multiple Myeloma|Relapsed Multiple Myeloma
Interventions: DRUG: IDP-023|DRUG: Rituximab|DRUG: Daratumumab|DRUG: Interleukin-2|DRUG: Cyclophosphamide|DRUG: Fludarabine|DRUG: Mesna
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diet Modulation of Bacterial Sulfur and Bile Acid Metabolism and Colon Cancer Risk
Status: ACTIVE_NOT_RECRUITING
Conditions: Colorectal Cancer
Interventions: OTHER: High taurine and saturated fat diet|OTHER: Low in taurine and saturated fat diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Evaluate The Clinical Effectiveness, Safety And Tolerability Of Sildenafil Used In Doses ≥20mg TID For The Treatment Of Pulmonary Arterial Hypertension
Status: COMPLETED
Conditions: Pulmonary Arterial Hypertension
Interventions: DRUG: sildenafil citrate
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of a Unique Co-created Intervention With Care Home Residents and University Students Following a Service-learning Methodology to Reduce Sedentary Behaviour.
Status: COMPLETED
Conditions: Physical Activity|Sedentary Behaviour|Care Home Residents
Interventions: BEHAVIORAL: Co-created intervention - Get Ready (GR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effects of Peri-operative Pregabalin Administration on Post-operative Analgesia in Patients Undergoing Coronary Bypass Grafting
Status: UNKNOWN
Conditions: Postoperative Pain.
Interventions: DRUG: Pregabalin|DRUG: Placebo/Lactose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Virtual Reality (VR) Treatment for Balance Problems in Traumatic Brain Injury (TBI)
Status: COMPLETED
Conditions: Traumatic Brain Injury
Interventions: BEHAVIORAL: Virtual Reality Based Exercise|BEHAVIORAL: Standard Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Obesity and Mindful Eating in Patients With Anxiety
Status: RECRUITING
Conditions: Anxiety|Obesity|Eating Behavior|Mindfulness|Inflammation|Self-Control
Interventions: BEHAVIORAL: Mindful Eating|BEHAVIORAL: Video Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Two Different Exercise Methods in Geriatrics
Status: COMPLETED
Conditions: Elderly People|Nursing Homes
Interventions: OTHER: Otago-based (slow rhythmic) exercise group|OTHER: LSVT BIG-based (large amplitude) exercise group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Multi-center Study to Assess the Efficacy and Safety of LX211 in Active Non-infectious Anterior Uveitis
Status: COMPLETED
Conditions: Uveitis, Anterior|Panuveitis
Interventions: DRUG: Placebo|DRUG: LX211|DRUG: LX211|DRUG: LX211
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation the Efficiency of Intravenous Dexmedetomidine Under Nasal Humidification Rapid Ventilation Device Without Intubation in Laryngoscope Microsurgery
Status: RECRUITING
Conditions: Dexmedetomidine
Interventions: PROCEDURE: Non-intubated Laryngomicrosurgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized, Double-blind Study to Evaluate Efficacy and Safety of Cenobamate Adjunctive Therapy in POS
Status: ACTIVE_NOT_RECRUITING
Conditions: Partial Seizure|Focal Seizure
Interventions: DRUG: Cenobamate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Whole-body Hyperthermia for Depression
Status: RECRUITING
Conditions: Major Depressive Disorder
Interventions: DEVICE: Active whole-body hyperthermia|DEVICE: Sham whole-body hyperthermia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Labor Induction With Misoprostol Versus Oxytocin in Women With Premature Rupture of Membranes
Status: UNKNOWN
Conditions: Prelabor Rupture of Membranes|Premature Rupture of Membrane
Interventions: DRUG: Misoprostol|DRUG: Oxytocin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Detection and Intervention for Mild and Moderate Lymphedema in Patients Treated for Breast Cancer
Status: TERMINATED
Conditions: Lymphedema|Breast Cancer
Interventions: DEVICE: Compression Sleeve|DEVICE: Short-Stretch Compression Bandage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Modafinil Treatment for Cocaine-Dependent Individuals
Status: COMPLETED
Conditions: Cocaine-Related Disorders
Interventions: DRUG: Low Dose Modafinil|DRUG: High Dose Modafinil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Intralesional MMR Vaccine,Intralesional Candidal Antigen&Topical Podophyllin in Treatment of Genital Warts
Status: UNKNOWN
Conditions: Condylomata Acuminata
Interventions: BIOLOGICAL: MMR vaccine|BIOLOGICAL: Candida antigen|DRUG: Topical Podophyllin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Next Generation INCEPTA Implantable Cardioverter Defibrillator (ICD) and Cardiac Resynchronization Therapy (CRT-D) Field Following Study
Status: COMPLETED
Conditions: Sudden Cardiac Death|Heart Failure
Interventions: DEVICE: INCEPTA ICD or CRT-D
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phase I Dose Escalation Study of BAY 1163877 (Rogaratinib) in Japanese Subjects With Refractory, Locally Advanced or Metastatic Solid Tumors
Status: COMPLETED
Conditions: Neoplasms
Interventions: DRUG: BAY1163877
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT