pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Modification of Cue Reactivity by Neurofeedback in Human Addiction
Status: UNKNOWN
Conditions: Alcohol Use Disorder (AUD)
Interventions: BEHAVIORAL: Treatment as usual (TAU) and neurofeedback (NFB)|BEHAVIORAL: mindfulness-based relapse prevention (MBRP) and NFB|BEHAVIORAL: TAU and sham NFB|BEHAVIORAL: MBT and sham NFB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Red Blood Cells Storage Duration on Biochemical Changes in Pediatric Patients
Status: COMPLETED
Conditions: Red Blood Cells Transfusion
Interventions: BIOLOGICAL: Red blood cells unit age 14 days or less|BIOLOGICAL: Red blood cells unit age more than 14 days
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Isolated and Combined Effect of a Low Carbohydrate Diet and Exercise in Hypoxia in Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Carbohydrate|Hypoxia|Exercise|Diabetes Mellitus, Type 2
Interventions: OTHER: Exercise in normoxia|OTHER: Control diet|OTHER: Exercise in hypoxia|OTHER: Low carbohydrate diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Replacement of Lamivudine by Telbivudine to Improve Renal Function
Status: COMPLETED
Conditions: Disorder Related to Transplantation|Virus Diseases|Injury Due to Exposure to External Cause
Interventions: DRUG: telbivudine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study of Oral JAK1/JAK2 Inhibitor INC424 in Adult Patients With Relapsed/Refractory Classical Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Hodgkin's Lymphoma
Interventions: DRUG: Ruxolitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Demonstrate the Efficacy, Safety and Tolerability of Intravenous Secukinumab up to 52 Weeks in Subjects With Active Psoriatic Arthritis
Status: COMPLETED
Conditions: Psoriatic Arthritis
Interventions: DRUG: AIN457 6 mg/kg i.v.|DRUG: Placebo|DRUG: AIN457 3 mg/kg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study on Safety and Efficacy of TQB2450 Injection Combined With Anlotinib Hydrochloride Capsule in Patients With Advanced Biliary Adenocarcinoma/Hepatocellular Carcinoma
Status: UNKNOWN
Conditions: Advanced Biliary Adenocarcinoma/Hepatocellular Carcinoma
Interventions: DRUG: TQB2450 injection|DRUG: Anlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Uterus Transplantation LD - Feasibility Study - Sahlgrenska - BMC
Status: COMPLETED
Conditions: Mrk Anomaly|Infertility, Female
Interventions: PROCEDURE: uterus transplantation surgery and IVF
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fruquintinib Plus S-1 and Raltitrexed (RSF) for mCRC
Status: RECRUITING
Conditions: Fruquintinib|S-1|Raltitrexed
Interventions: DRUG: Fruquintinib|DRUG: S-1|DRUG: raltitrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Remote Ischemic Conditioning Treatment for Community-based Essential Hypertension
Status: RECRUITING
Conditions: Essential Hypertension
Interventions: DEVICE: Patients are treated with previous antihypertensive treatment plus remote ischemic conditioning.|OTHER: Previous antihypertensive treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bevacizumab, Lenalidomide, and Dexamethasone in Patients With Relapsed or Refractory Stage II or III Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma in Relapse|Stage II Multiple Myeloma|Stage III Multiple Myeloma
Interventions: BIOLOGICAL: bevacizumab|DRUG: lenalidomide|DRUG: dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Liberal Versus Restrictive Transfusion Guidelines for Preterm Infants
Status: COMPLETED
Conditions: Infant, Premature|Anemia|Intracranial Hemorrhages|Leukomalacia, Periventricular|Apnea
Interventions: PROCEDURE: Red blood cell transfusion guidelines
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Safety, Tolerability, Pharmacokinetics (PK) and Pharmacodynamics (PD) of Multiple Ascending Doses of AZD5069 in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: AZD5069|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: S0408: Capecitabine, Oxaliplatin, and Bevacizumab in Pts Undergoing Surgery for Liver Mets From Colorectal Cancer
Status: WITHDRAWN
Conditions: Colorectal Cancer|Metastatic Cancer
Interventions: BIOLOGICAL: bevacizumab|DRUG: capecitabine|DRUG: oxaliplatin|PROCEDURE: conventional surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Betaine Effect in Speed-strength Athletes
Status: UNKNOWN
Conditions: Supplementation|Sport
Interventions: DIETARY_SUPPLEMENT: Betaine supplementation|DIETARY_SUPPLEMENT: Placebo treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Multiple Component Mobile-aid Pain Reduction Intervention to Decrease Myofascial Pain
Status: NOT_YET_RECRUITING
Conditions: Myofascial Pain Syndrome
Interventions: BEHAVIORAL: Multiple Component Mobile-Aid Pain Reduction Intervention|OTHER: Osteopathic Manipulation Treatment|OTHER: Sham Osteopathic Manipulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Iliac Branch Excluder ReGistry (IceBERG)
Status: ACTIVE_NOT_RECRUITING
Conditions: Abdominal Aortic Aneurysms|Common Iliac Aneurysms|Aneurysm
Interventions: DEVICE: The Gore® EXCLUDER® ILIAC BRANCH Endoprosthesis.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical Research on the Application of Single-channel Uterine Fibroid Morcellation System in Laparoscopic Myomectomy
Status: NOT_YET_RECRUITING
Conditions: Leiomyoma, Uterine
Interventions: DEVICE: single-channel uterine fibroid morcellation system|DEVICE: Multi-channel specimen retrieval bag + conventional laparoscopic uterine fibroid morcellator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II Trial of Alisertib (MLN8237) in Salvage Malignant Mesothelioma
Status: COMPLETED
Conditions: Lung Cancer|Mesothelioma
Interventions: DRUG: Alisertib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Physiological Response to Protein and Energy-enhanced Food Products During Winter Military Training
Status: COMPLETED
Conditions: Military Operational Stress Reaction|Malnutrition (Calorie)|Weight Loss|Muscle Wasting
Interventions: DIETARY_SUPPLEMENT: EAA|DIETARY_SUPPLEMENT: Energy Dense|DIETARY_SUPPLEMENT: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Natural History Study of Pyruvate Dehydrogenase Deficiency
Status: RECRUITING
Conditions: Pyruvate Dehydrogenase Complex Deficiency|Pyruvate Dehydrogenase E1 Alpha Deficiency|Pyruvate Dehydrogenase E1-Beta Deficiency|Pyruvate Dehydrogenase E2 Deficiency|Pyruvate Dehydrogenase Phosphatase Deficiency
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A 6-week Study to Evaluate the Safety and Efficacy of Quillichew ERCT in 4-5 Year Old Children With ADHD.
Status: WITHDRAWN
Conditions: Attention Deficit Hyperactivity Disorder (ADHD)|Attention Deficit Hyperactivity Disorder
Interventions: DRUG: methylphenidate HCl ERCT|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of a Psychological Intervention on Antiretroviral Therapy and Mental Health Outcomes in HIV-positive Adults in Zimbabwe
Status: COMPLETED
Conditions: Mental Disorder|HIV Infections
Interventions: BEHAVIORAL: Friendship bench intervention|OTHER: Enhanced Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of Ultrashort-term Heat Inactivation of Cytomegalovirus (CMV) Containing Raw Breast Milk to Prevent CMV-infection of Preterm Infants
Status: COMPLETED
Conditions: Cytomegalovirus Infection|Preterm Infants
Interventions: PROCEDURE: ultrashort heat inactivation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: |Primary Purpose: PREVENTION
Clinical trial: Renal Denervation on Quality of 24-hr BP Control by Ultrasound In Resistant Hypertension
Status: COMPLETED
Conditions: Hypertension|Vascular Diseases
Interventions: DEVICE: PRDS-001 Renal Denervation Ultrasound System|PROCEDURE: Sham Procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Applying a Person-Centered Approach to Enhance Cognitive Training in Senior Living Community Residents With Mild Cognitive Impairment
Status: COMPLETED
Conditions: Mild Cognitive Impairment
Interventions: BEHAVIORAL: PEP|BEHAVIORAL: CCI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: To Evaluate Plasma and Pulmonary Pharmacokinetics of GSK2140944
Status: COMPLETED
Conditions: Infections, Bacterial
Interventions: DRUG: GSK2140944 (Single dose)|DRUG: GSK2140944 (Multiple dose)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MabRella Study: A Study to Evaluate the Safety of Switching From Intravenous to Subcutaneous Administration of Rituximab During First-Line Treatment for Lymphoma
Status: COMPLETED
Conditions: Lymphoma, Non Hodgkin
Interventions: DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study About Effect of Preoperative Bowel Preparation Versus no Bowel Preparation Before Spinal Surgery
Status: COMPLETED
Conditions: Constipation|Ileus|Surgery
Interventions: DRUG: Docusate natrium and sorbitol|DRUG: Bisacodyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Role of Pre-existing Cross-reactive Antibodies in Determining the Efficacy of Vaccination in Humans
Status: COMPLETED
Conditions: Yellow Fever|Encephalitis, Japanese
Interventions: BIOLOGICAL: Japanese Encephalitis vaccine|BIOLOGICAL: Yellow Fever vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: A Crossover Study to Evaluate Relative Bioavailability of Two JNJ-54781532 Tablet Formulations in Healthy Adult Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Formulation 2|DRUG: Formulation 1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: B Vitamin Status in Premature and Small for Gestational Age(SGA) Infants
Status: COMPLETED
Conditions: Biochemical Cobalamin Status|Motor Neurodevelopment
Interventions: DIETARY_SUPPLEMENT: Hydroxycobalamin|DIETARY_SUPPLEMENT: Sham injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study To Estimate The Amount Of CP-690,550 (Study Drug) That Is Absorbed Into The Blood Of Healthy Subjects Following Oral Administration Of CP-690,550 In Tablet Form
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Tasocitinib 10 mg oral tablet|DRUG: Tasocitinib 10 mg IV Infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: MP470 in Treating Patients With Unresectable or Metastatic Solid Tumor or Lymphoma
Status: TERMINATED
Conditions: Lymphoma|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: multitargeted receptor tyrosine kinase inhibitor MP470|OTHER: laboratory biomarker analysis|OTHER: pharmacological study|PROCEDURE: positron emission tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: To Evaluate the Blockade of CGRP in Preventing PACAP-38 Induced Migraine-like Attacks With AMG 334 in Migraine Patients
Status: COMPLETED
Conditions: Migraine
Interventions: DRUG: Erenumab|DRUG: Placebo|DRUG: PACAP-38 Challenge Agent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Pharmacological Effects of Neurapas® Balance and Pascoflair® 425 mg on Brain Activity in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Neurapas balance|DRUG: Pascoflair 425 mg|DRUG: P-Tabletten weiß
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Combination Oral Acetazolamide and Intravenous Furosemide on Acute Decompensated Heart Failure Outcomes
Status: RECRUITING
Conditions: Acute Decompensated Heart Failure
Interventions: DRUG: Oral Acetazolamide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Observational Study for Assessing Treatment and Outcome of Patients With Primary Brain Tumours Using cIMPACT-NOW and 2021 WHO Classification
Status: RECRUITING
Conditions: Glioma|Glioneuronal Tumor|Choroid Plexus Tumor|Pineal Tumors|Germ Cell Tumor|Tumor of the Sellar Region|Diffuse Midline Glioma, H3 K27M-Mutant|Ependymoma|Embryonal Tumor|Pineal Tumor|Hemangiopericytoma|Hemangioblastoma|Melanocytic Tumor of CNS
Interventions: OTHER: Observational
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Serious Game-based Intervention in Gait Rehabilitation for Children With Cerebral Palsy
Status: RECRUITING
Conditions: Cerebral Palsy|Gait Disorders, Neurologic
Interventions: OTHER: Serious game ARROW CP|OTHER: Treadmill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Ultrasound Guided Erector Spinae Plane Block
Status: COMPLETED
Conditions: Hemodynamic Instability|Patient Satisfaction|Postoperative Pain|Regional Block
Interventions: PROCEDURE: Erector spinae plane block|OTHER: control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: DIAGNOSTIC
Clinical trial: Providing Hygiene Education Using the Teach-back Method to Pregnant Women Diagnosed With Urinary Tract Infections
Status: RECRUITING
Conditions: Urinary Tract Infections During Pregnancy
Interventions: OTHER: Providing hygiene education based on the method of teaching what has been learned in the context of a genital hygiene guide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Healthy for Two-Home Visiting (H42-HV): Health Coaching for Pregnant Women
Status: RECRUITING
Conditions: Postpartum Weight Retention|Pregnancy Weight Gain|Overweight and Obesity|Behavior, Health
Interventions: BEHAVIORAL: Healthy for Two-Health Coaching (H42)|BEHAVIORAL: Maintain Healthy in Pregnancy and Postpartum(mHIPP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Korean Nationwide Multicenter Pooled Registry of Drug-Eluting Stents
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DEVICE: Biomatrix; Biomatrix Flex; Nobori|DEVICE: Xience Prime|DEVICE: Xience V/Promus; Cypher|DEVICE: DP-ZES-RI|DEVICE: Endeavor; Resolute
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Botulinum Toxin Treatment of Glabellar Lines: Efficacy and Safety Study II
Status: COMPLETED
Conditions: Glabellar Frown Lines
Interventions: DRUG: Botulinum Toxin A|DRUG: Placebo|DRUG: Botulinum Toxin A - Open Label
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intramedullary Nail Versus Hip Arthroplasty in Unstable Trochanteric Hip Fractures
Status: RECRUITING
Conditions: Hip Injuries and Disorders|Hip Fractures
Interventions: PROCEDURE: Intramedullary nail|PROCEDURE: Hip arthroplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combined Intense Pulsed Light (IPL) With Fractional Erbium:YAG Laser Ablation in Scar Prevention
Status: UNKNOWN
Conditions: Intense Pulsed Light|Erbium-yttrium Aluminum Garnet Laser|Scar Prevention
Interventions: DEVICE: fractional Er:YAG laser|DEVICE: Intense pulse light
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimal Dose of Extracorporeal Shock Wave Therapy After Botulinum Toxin Type A Injection for Post-stroke Spasticity
Status: UNKNOWN
Conditions: Post-Stroke Elbow Spasticity
Interventions: PROCEDURE: Extracorporeal shock wave therapy 60mj|PROCEDURE: Extracorporeal shock wave therapy 120mj|PROCEDURE: non extracorporeal shock wave therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: New Technology for Individualised, Intensive Training of Gait After Stroke Study I
Status: TERMINATED
Conditions: Stroke|Ambulation Difficulty|Hemiparesis
Interventions: DEVICE: Hybrid Assistive Limb (HAL)|OTHER: Conventional gait training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study To Evaluate An Interaction Between Maraviroc And Raltegravir In Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Maraviroc|DRUG: Maraviroc|DRUG: Raltegravir|DRUG: Raltegravir
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Testing of INSTI™ HIV-1 Antibody Test Kit in Volunteer Subjects at Risk for HIV Infection
Status: COMPLETED
Conditions: HIV Infections
Interventions: OTHER: Behavioral counseling|DEVICE: HIV-1 Antibody Test Kit
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE|Primary Purpose: DIAGNOSTIC
Clinical trial: Assessment of the Efficacy and Barrier Protection of Two Cosmetic Products
Status: COMPLETED
Conditions: Aged Skin
Interventions: OTHER: C - pH 4 Cosmetic Product WO 3741|OTHER: D - pH 5.8 Cosmetic Product WO 4081-1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Different Types of Higher Dietary Protein Intake on Sleep Quality in Singapore Older Adults
Status: RECRUITING
Conditions: Sleep|Gut Microbiome|Cardiometabolic Risk
Interventions: OTHER: Dietary protein
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pharmacokinetic Study Evaluating Staccato® Alprazolam 1 mg Inhaler in Smokers Versus Non-Smokers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Staccato Alprazolam 1 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study on Evaluation of Zoledronic Acid to Prevent Bone Loss in Men Receiving Androgen Deprivation Therapy for Prostate Cancer
Status: COMPLETED
Conditions: Prostatic Neoplasms|Bone Density
Interventions: DRUG: Zolderonic acid (Zometa)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Correlation and Relationship Between Chromaticity Parameters and Treatment Satisfaction Before and After Tooth Bleaching
Status: UNKNOWN
Conditions: Bleaching; Satisfactory
Interventions: OTHER: Common toothpaste
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Indacaterol in Heart Failure Patients: Any Role on Lung Fluid Regulation
Status: COMPLETED
Conditions: Heart Failure
Interventions: DRUG: Indacaterol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Oral Chloral Hydrate and Combination of Intranasal Dexmedetomidine and Ketamine for Procedural Sedation in Children
Status: RECRUITING
Conditions: Sedation
Interventions: DRUG: Intranasal dexmedetomidine and ketamine|DRUG: Oral chloral hydrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Dose Escalation Phase I Study to Assess the Safety and Clinical Activity of Multiple Cancer Indications
Status: UNKNOWN
Conditions: Acute Myeloid Leukemia/Myelodysplastic Syndrome|Multiple Myeloma (MM)
Interventions: BIOLOGICAL: NKR-2 cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Birch Pollen Immunotherapy in Local Allergic Rhinitis
Status: COMPLETED
Conditions: Allergic Rhinitis|Allergic Reaction
Interventions: DRUG: Purethal Birch immunotherapy|OTHER: Placebo and symptomatic treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Combining APL-101 With Frontline Osimertinib in Patients With EGFR-mutated Metastatic Non-small Cell Lung Cancer (NSCLC)
Status: RECRUITING
Conditions: Metastatic Non Small Cell Lung Cancer
Interventions: DRUG: APL-101|DRUG: Osimertinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Nasal Decolonisation of Staphylococcus Aureus (SA) and the Safety and Tolerability of XF-73 Nasal Gel in Healthy Subjects
Status: COMPLETED
Conditions: Staphylococcus Aureus Infection
Interventions: DRUG: XF-73 nasal gel|DRUG: Placebo nasal gel|OTHER: Chlorhexidine gluconate 2% topical cloths
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Impact of Phosphate Metabolism on Healthy Aging
Status: SUSPENDED
Conditions: Hypophosphatemia|Rickets|Hypercalciuria|XLH|HHRH
Interventions: DRUG: phosphate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Safety of Cettum for Perennial Allergic Rhinitis
Status: UNKNOWN
Conditions: Rhinitis, Allergic
Interventions: PROCEDURE: Cettum|PROCEDURE: Acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Safety and Preliminary Efficacy of AZD0156 at Increasing Doses Alone or in Combination With Other Anti-cancer Treatment in Patients With Advanced Cancer
Status: COMPLETED
Conditions: Advanced Solid Tumours
Interventions: DRUG: AZD0156|DRUG: Olaparib|DRUG: irinotecan|DRUG: Fluorouracil|DRUG: Folinic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Designed to Optimize the Treatment of Primary Pneumothorax
Status: RECRUITING
Conditions: Primary Spontaneous Pneumothorax|Pleural Disease
Interventions: PROCEDURE: VATS bullectomy and mechanical pleuradesis.|PROCEDURE: Chest tube insertion|DRUG: Epidural|RADIATION: High-resolution Computer Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety of and Immune Response to a Dengue Virus Vaccine (rDEN2/4delta30[ME]) in Healthy Adults
Status: COMPLETED
Conditions: Dengue Fever
Interventions: BIOLOGICAL: rDEN2/4delta30(ME) Vaccine|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Antineoplaston Therapy in Treating Patients With Primary Central Nervous System Lymphoma
Status: WITHDRAWN
Conditions: Primary Central Nervous System Lymphoma
Interventions: DRUG: antineoplaston A10|DRUG: antineoplaston AS2-1|PROCEDURE: alternative product therapy|PROCEDURE: biological therapy|PROCEDURE: biologically based therapies|PROCEDURE: cancer prevention intervention|PROCEDURE: complementary and alternative therapy|PROCEDURE: differentiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: R-ICE and Lenalidomide in Treating Patients With First-Relapse/Primary Refractory Diffuse Large B-Cell Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Recurrent B-Cell Non-Hodgkin Lymphoma|Recurrent Diffuse Large B-Cell Lymphoma|Recurrent Primary Mediastinal (Thymic) Large B-Cell Lymphoma|Recurrent Transformed Non-Hodgkin Lymphoma|Refractory B-Cell Non-Hodgkin Lymphoma|Refractory Diffuse Large B-Cell Lymphoma|Refractory Primary Mediastinal (Thymic) Large B-Cell Lymphoma|Refractory Transformed Non-Hodgkin Lymphoma
Interventions: DRUG: Carboplatin|DRUG: Etoposide|DRUG: Ifosfamide|OTHER: Laboratory Biomarker Analysis|DRUG: Lenalidomide|BIOLOGICAL: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tisleilizumab (PD-1 Antibody) and Chemoradiotherapy in Locoregionally-advanced Nasopharyngeal Carcinoma
Status: NOT_YET_RECRUITING
Conditions: Nasopharyngeal Neoplasms
Interventions: DRUG: Tis-U-Sol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Open Label Study of the Effect of Telaprevir in Combination With Ribavirin and Peginterferon on HCV Infection in Stable Liver Transplant Patients
Status: TERMINATED
Conditions: Hepatitis C
Interventions: DRUG: Telaprevir|DRUG: Ribavirin|DRUG: Pegylated Interferon Alfa-2a|DRUG: Immunosuppressant Regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of External Warming During Laparoscopic Bariatric Surgery
Status: TERMINATED
Conditions: Hypothermia|Morbid Obesity|Bariatric Surgery Candidate
Interventions: OTHER: No external heating used during surgery|OTHER: External heating blanket used during surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vitamin Supplementation After Bariatric Surgery
Status: UNKNOWN
Conditions: Complications of Bariatric Procedures|Avitaminosis
Interventions: DIETARY_SUPPLEMENT: Chewable Multivitamin with Iron|DIETARY_SUPPLEMENT: PatchMD Vitamin D3/Calcium Patch|DIETARY_SUPPLEMENT: PatchMD Multivitamin Patch|DIETARY_SUPPLEMENT: PatchMD B12 Energy Plus Patch|DIETARY_SUPPLEMENT: Chewable Calcium|DIETARY_SUPPLEMENT: Quick Dissolve B12
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Sacral Nerve Stimulation for Anal Incontinence and Bowel Control
Status: COMPLETED
Conditions: Fecal Incontinence and Constipation
Interventions: DEVICE: Type: Implantable neurostimulator; InterStim
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Drug Interaction Potential Between Dolutegravir and Simeprevir in HIV/HCV Seronegative Volunteers
Status: COMPLETED
Conditions: HIV|Hepatitis C
Interventions: DRUG: dolutegravir|DRUG: simeprevir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Capecitabine Plus Aflibercept as Maintenance Therapy Following Capecitabine Plus Oxaliplatin Plus Aflibercept in Patients With Metastatic Colorectal Cancer
Status: WITHDRAWN
Conditions: Colorectal Cancer Metastatic
Interventions: DRUG: Capecitabine|DRUG: Aflibercept AVE0005|DRUG: Oxaliplatin SR96669
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cost-effectiveness of Two Forms of DOTS in a Demonstration Area of the DOTS Strategy in Colombia
Status: COMPLETED
Conditions: Tuberculosis, Pulmonary
Interventions: OTHER: Intramural|OTHER: Extramural
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Functional Changes in the Stomach and Esophagus After One Anastomosis Gastric Bypass- OAGB
Status: RECRUITING
Conditions: Obesity, Morbid|GERD|Ulcer, Gastric
Interventions: PROCEDURE: One Anastomosis Gastric Bypass (OAGB)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Rivaroxiban Compare With Vitamin K Antagonist Warfarin
Status: WITHDRAWN
Conditions: Mitral Valve Stenosis|Atrial Fibrillation
Interventions: DRUG: Rivaroxaban 15 mg|DRUG: Warfarin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Disitamab Vedotin Combined With Radiotherapy for Bladder Preservation
Status: NOT_YET_RECRUITING
Conditions: Urothelial Carcinoma
Interventions: DRUG: Disitamab Vedotin|RADIATION: radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose-Escalating Study of Pfs230D1 in Combination With R21 in Matrix-M in African Adults
Status: NOT_YET_RECRUITING
Conditions: Prevention of Malaria Transmission and Clinical Malaria
Interventions: BIOLOGICAL: R21|BIOLOGICAL: Pfs230D1-CRM197|BIOLOGICAL: Pfs230D1-EPA|OTHER: Matrix-M
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Testing the Addition of an Anti-cancer Drug, Copanlisib, to the Usual Immunotherapy (Nivolumab With or Without Ipilimumab) in Patients With Advanced Solid Cancers That Have Changes in the Following Genes: PIK3CA and PTEN
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Malignant Solid Neoplasm|Metastatic Malignant Solid Neoplasm|Unresectable Malignant Solid Neoplasm
Interventions: PROCEDURE: Biopsy|PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|DRUG: Copanlisib Hydrochloride|PROCEDURE: Echocardiography|BIOLOGICAL: Ipilimumab|BIOLOGICAL: Nivolumab|PROCEDURE: X-Ray Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of rhTPO's Prophylactic Treatment of CTIT in Patients With High Risk of Cardiac Injury
Status: RECRUITING
Conditions: Cancer Treatment Induced Thrombocytopenia
Interventions: DRUG: rhTPO|DRUG: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: First Line Comparative Study of EN3348 (MCC) vs BCG in NMIBC
Status: WITHDRAWN
Conditions: Bladder Cancer
Interventions: BIOLOGICAL: Mycobacterial Cell-Wall DNA Complex|BIOLOGICAL: Bacillus Calmette-Guerin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Placebo Controlled Trial of the Dopamine D-2 Receptor Agonist Ropinirole in Treatment of 60 Patients With Refractory Bipolar Depression.
Status: UNKNOWN
Conditions: Bipolar Disorder|Major Depressive Disorder
Interventions: DRUG: ropinirole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Phase 3b Study to Evaluate Advagraf in Combination With Mycophenolate Mofetil and Basiliximab in Liver Transplantation
Status: COMPLETED
Conditions: Liver Transplantation
Interventions: DRUG: Advagraf|DRUG: Mycophenolate Mofetil|DRUG: Basiliximab|DRUG: Corticosteroids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of TX103 CAR-T Cell Therapy for Recurrent or Progressive Grade 4 Glioma.
Status: NOT_YET_RECRUITING
Conditions: High-grade Glioma|WHO Grade Ⅳ Glioma
Interventions: BIOLOGICAL: Anti-B7-H3 Chimeric Antigen Receptor T-Cell (CAR-T Cell) Injection/TX103
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nivolumab and the Antagonistic CSF-1R Monoclonal Antibody Cabiralizumab (BMS-986227) in Patients With Relapsed/Refractory Peripheral T Cell Lymphoma
Status: COMPLETED
Conditions: Peripheral T Cell Lymphoma
Interventions: DRUG: Nivolumab|DRUG: cabiralizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Arginine and Buphenyl in Patients With Argininosuccinic Aciduria (ASA), a Urea Cycle Disorder
Status: COMPLETED
Conditions: Argininosuccinic Aciduria|Amino Acid Metabolism, Inborn Errors|Urea Cycle Disorders
Interventions: DRUG: Sodium Phenylbutyrate|DRUG: Arginine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Sintilimab Combined With Lenvatinib in Local Advanced Hepatocellular Carcinoma
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma
Interventions: BIOLOGICAL: Sintilimab|DRUG: Lenvatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Retrospective Examination of Initial Care of Severe Bacterial Infections of the Child
Status: COMPLETED
Conditions: Bacterial Infection
Interventions: OTHER: Retrospective examination by experts whether care given fo child admitted at the ICU for suspicion of bacterial infection (not nosocomial) was optimal or not
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effects of Mindfulness Based Therapy on Illness and Depression in Cardiac Rehab Phase-i
Status: RECRUITING
Conditions: Coronary Artery Stenosis
Interventions: OTHER: cardiac rehabilitation phase I protocols|OTHER: Cardiac rehab phase I protocols + Mindfullness base therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Adipose Mesenchymal Stem Cells (AMSC) for Treatment of Ulcerative Colitis
Status: UNKNOWN
Conditions: Ulcerative Colitis (UC)
Interventions: BIOLOGICAL: Adipose-cord mesenchymal stromal cells (A-MSCs)|OTHER: Conventional drugs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Equal Oral Health in Children: The Hageby-model
Status: COMPLETED
Conditions: Dental Caries in Children|Economic Problems|Infant Conditions|Child, Preschool|Pregnancy Related|Educational Problems|Risk Reduction
Interventions: BEHAVIORAL: Dental education - Motivational Interviewing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety, Tolerability, Pharmacodynamics and Pharmacokinetics of BI 653048 BS H3PO4 Capsule Assessing Endotoxin-induced Inflammatory Response in Healthy Male Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BI 653048 BS|DRUG: Prednisolone low|DRUG: Prednisolone high|DRUG: Placebo|DRUG: sodium chloride infusion|DRUG: endotoxin escherichia coli (E. coli) lipopolysaccharide (LPS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Effects of Hypocaloric Diets With Different Glycemic Loads on Pulse Wave Velocity
Status: UNKNOWN
Conditions: Glycemic Index|Overweight|Obesity|Pulse Wave Velocity
Interventions: OTHER: Low glycemic load diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neoantigen-primed DC Vaccines Therapy for Refractory Lung Cancer
Status: UNKNOWN
Conditions: Carcinoma, Non-Small Cell Lung|Carcinoma, Small Cell Lung
Interventions: BIOLOGICAL: Neoantigen loaded DC vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Advancing Cardiac Care Unit-based Rapid Assessment and Treatment of hypErcholesterolemia
Status: RECRUITING
Conditions: Familial Hypercholesterolemia|Familial Hypercholesterolemia Due to Genetic Defect of Apolipoprotein B|Familial Hypercholesterolemia Due to Heterozygous LDL Receptor Mutation|Familial Hypercholesterolemia - Heterozygous|Acute Coronary Syndrome|NSTEMI - Non-ST Segment Elevation MI|STEMI|Familial Hypercholesterolemia With Hyperlipemia
Interventions: DIAGNOSTIC_TEST: Research-based genetic test for Familial Hypercholesterolemia
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: MART-1 Antigen With or Without TLR4 Agonist GLA-SE in Treating Patients With Stage II-IV Melanoma That Has Been Removed by Surgery
Status: COMPLETED
Conditions: Stage IIA Skin Melanoma|Stage IIB Skin Melanoma|Stage IIC Skin Melanoma|Stage IIIA Skin Melanoma|Stage IIIB Skin Melanoma|Stage IIIC Skin Melanoma|Stage IV Skin Melanoma
Interventions: BIOLOGICAL: MART-1 Antigen|DRUG: TLR4 Agonist GLA-SE|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Bio-availability of Artemether-Lumefantrine in Severely Malnourished Children
Status: COMPLETED
Conditions: Malaria|Severe Acute Malnutrition
Interventions: DRUG: Artemether-lumefantrine fixed combination
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Training of Psychosocial Skills Based on Cognitive Behavioural Therapy for Patients With Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson's Disease|Mild Cognitive Impairment
Interventions: BEHAVIORAL: Psycho-social CBT based training|BEHAVIORAL: Unspecific group training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Moderated-fat Diet Complemented With Green Tea Reduces oxLDL and Fat Mass in Obese Women
Status: COMPLETED
Conditions: Nutritional and Metabolic Disease
Interventions: OTHER: Nutritional intervention|DIETARY_SUPPLEMENT: Green tea
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Progevera 10 mg® Versus Orgalutran® in Ovarian Stimulation Cycles of Oocyte Donors
Status: COMPLETED
Conditions: Infertility
Interventions: DRUG: Progevera|DRUG: Orgalutran
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study to Assess the Efficacy and Safety of Raxone in LHON Patients
Status: COMPLETED
Conditions: Leber's Hereditary Optic Neuropathy (LHON)
Interventions: DRUG: Idebenone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Everolimus With and Without Temozolomide in Adult Low Grade Glioma
Status: TERMINATED
Conditions: Low Grade Glioma|World Health Organization (WHO) Grade II Astrocytomas|Oligodendrogliomas|Mixed Oligoastrocytomas
Interventions: DRUG: Everolimus|DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Levetiracetam in Cocaine-Abusing Methadone Maintained Patients
Status: COMPLETED
Conditions: Cocaine Dependence|Opioid Dependency
Interventions: DRUG: levetiracetam|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Rifaximin and Norfloxacin for Prevention of SBP in Adults With Decompensated Cirrhosis
Status: COMPLETED
Conditions: Cirrhosis, Liver
Interventions: DRUG: Rifaximin 550 mg twice a day and Norfloxacin 400 mg once a day
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A 24 Week, Multicenter, Prospective, Open-labeled, Single-arm, Exploratory Phase 4 Clinical Trial to Evaluate the Safety and Efficacy of Lobeglitazone in Decreasing Intrahepatic Fat Contents in Type 2 Diabetes With NAFLD
Status: COMPLETED
Conditions: Type 2 Diabetes|Non-alcoholic Fatty Liver Disease
Interventions: DRUG: Oral administration of Lobeglitazone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Atrial Fibrillation Burden and Long-term Risk of Thromboembolic Complications- the FinCV-4 Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Atrial Fibrillation|Stroke, Ischemic
Interventions: DRUG: Anticoagulation Therapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: ITCH Trial: Protocol for a Randomized, Double Blind Placebo-controlled Trial
Status: COMPLETED
Conditions: Cerebral Hemorrhage
Interventions: DRUG: Tranexamic Acid 500 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Voluven® in Paediatric Patients
Status: COMPLETED
Conditions: Cardiac Surgery|Cardiopulmonary Bypass
Interventions: DRUG: HES 130/0.4 (6%) in sodium chloride (Voluven®, solution for infusion), Human serum albumin (HSA 50g/L)|DRUG: Human serum albumin (HSA 50g/L)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Local Anesthetic Response in Ehlers-Danlos Syndrome (EDS) and Healthy Volunteers
Status: ENROLLING_BY_INVITATION
Conditions: Ehlers-Danlos Syndrome|Anesthesia, Local
Interventions: DRUG: 0.9% Sodium Chloride Injection|DRUG: Lidocaine Injection 2%|DRUG: Bupivacaine Injection 0.5%
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: An Evaluation of Low Level Laser Light Therapy for Autistic Disorder 2
Status: COMPLETED
Conditions: Autistic Disorder
Interventions: DEVICE: Erchonia HLS Laser|DEVICE: Placebo Laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Glycemic And Blood Pressure Control In Type 2 Diabetes, In A Primary Care Unit: A Staged Management Strategy
Status: UNKNOWN
Conditions: Diabetes Mellitus|Arterial Hypertension
Interventions: DRUG: Metformin|DRUG: Glybenclamide|DRUG: NPH insulin|DRUG: Hydrochlorothiazide|DRUG: Propranolol|DRUG: Captopril|DRUG: Amlodipine
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Positron Emission Tomography (PET) Imaging of Neuroinflammation in Patients With Neurological Dysfunction After Severe Acute Respiratory Syndrome Coronavirus 2 (SARS CoV 2) Infection
Status: RECRUITING
Conditions: SARS CoV-2 Post-Acute Sequelae
Interventions: DRUG: DPA-714 PET/MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC