pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: D081AC00001 Food Interaction With Olaparib Capsule in Patients With Solid Tumours
Status: COMPLETED
Conditions: Solid Tumours
Interventions: DRUG: Olaparib|OTHER: Dietary Fasted|OTHER: Dietary standard|OTHER: Dietary High Fat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Blood Pressure, Cerebral Blood Flow and Cognition in Spinal Cord Injury
Status: COMPLETED
Conditions: Spinal Cord Injury
Interventions: DRUG: Midodrine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Innovative Ultrasonic Techniques for Non-invasive Diagnosis of Liver Fibrosis in Patients With Chronic Viral Hepatitis B or C
Status: COMPLETED
Conditions: Liver Fibrosis
Interventions: DEVICE: Fibroscan® of Echosens, Aixplorer® of Supersonic Imagine, Aplio XG of Toshiba, QRS software developed by Pr I.Bricault, Acuson S2000 of Siemens
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Povidone Iodine Mouthwash, Gargle, and Nasal Spray to Reduce Naso- Pharyngeal Viral Load in Patients With COVID-19
Status: COMPLETED
Conditions: COVID-19
Interventions: DRUG: Povidone-Iodine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Levetiracetam in Essential Tremor
Status: COMPLETED
Conditions: Essential Tremor
Interventions: DRUG: levetiracetam|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Acetazolamide on Right Heart Function at Rest in Lowlanders With COPD Traveling to High Altitude
Status: RECRUITING
Conditions: Right Heart Function|Chronic Obstructive Pulmonary Disease|Altitude Sickness
Interventions: DRUG: Acetazolamide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of the Bromodomain (BRD) and Extra-Terminal Domain (BET) Inhibitors BMS-986158 and BMS-986378 in Pediatric Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Solid Tumor, Childhood|Lymphoma|Brain Tumor, Pediatric
Interventions: DRUG: BMS-986158|DRUG: BMS-986378
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Dietary Intervention in Intermediate Risk Prostate Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Adenocarcinoma|Stage I Prostate Cancer AJCC v8|Stage II Prostate Cancer AJCC v8|Stage IIA Prostate Cancer AJCC v8|Stage IIB Prostate Cancer AJCC v8|Stage IIC Prostate Cancer AJCC v8|Stage IIIA Prostate Cancer AJCC v8
Interventions: OTHER: Dietary Intervention|PROCEDURE: Radical Prostatectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Study is Being Done to See if Taking the Drug Valganciclovir Can Prevent CMV Infection.
Status: COMPLETED
Conditions: Bone Marrow Stem Cell Transplant
Interventions: DRUG: Valganciclovir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: The Influence of Polymeric Versus Oligomeric Enteral Feeding on Tolerance and Nutritional Status in Paediatric Intensive Care Pilot
Status: RECRUITING
Conditions: Enteral Feeding Intolerance
Interventions: DIETARY_SUPPLEMENT: Oligomeric enteral feeding|DIETARY_SUPPLEMENT: Polymeric enteral feeding
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Pamiparib and Temozolomide for the Treatment of Hereditary Leiomyomatosis and Renal Cell Cancer
Status: WITHDRAWN
Conditions: Clear Cell Papillary Renal Neoplasm|Collecting Duct Carcinoma|Hereditary Leiomyomatosis and Renal Cell Carcinoma|Hereditary Papillary Renal Cell Carcinoma|Metastatic Renal Cell Carcinoma|Metastatic Unclassified Renal Cell Carcinoma|Papillary Renal Cell Carcinoma|Stage III Renal Cell Cancer American Joint Committee on Cancer (AJCC) v8|Stage IV Renal Cell Cancer AJCC v8|Tubulocystic Renal Cell Carcinoma|Unresectable Renal Cell Carcinoma
Interventions: DRUG: Pamiparib|DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating the Safety, Pharmacokinetics, and Activity of RO7656594 In Participants With Advanced or Metastatic Prostate Cancer
Status: RECRUITING
Conditions: Advanced Prostate Cancer|Metastatic Prostate Cancer
Interventions: DRUG: RO7656594
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stem Cell Transplant in Treating Patients With Acute Myeloid Leukemia
Status: TERMINATED
Conditions: Leukemia
Interventions: BIOLOGICAL: sargramostim|DRUG: busulfan|DRUG: cyclophosphamide|DRUG: dexamethasone|DRUG: etoposide|PROCEDURE: bone marrow transplantation|PROCEDURE: hematopoietic stem cell transplantation|PROCEDURE: peripheral blood stem cell transplantation|RADIATION: total-body irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of a Progressive Treadmill Training Protocol for Parkinson's Disease
Status: RECRUITING
Conditions: Parkinson Disease|Gait, Festinating|Fall Due to Loss of Equilibrium|Gait, Unsteady|Gait, Shuffling
Interventions: DEVICE: AVR Treadmill training with C-Mill|DEVICE: Conventional Treadmill training with C-Mill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: TDT 067 Open Label Multi-Dose Onychomycosis Study
Status: COMPLETED
Conditions: Onychomycosis
Interventions: DRUG: TDT067 and Lamisil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Defining Strategies for Improving Endothelial and Fibrinolytic Dysfunction in Obesity
Status: TERMINATED
Conditions: Metabolic Syndrome X
Interventions: DRUG: Eplerenone|DRUG: Ramipril
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of Olopatadine 0.6% and Fluticasone Proprionate 50mcg Nasal Sprays in a Two Week Seasonal Allergic Rhinitis Trial
Status: COMPLETED
Conditions: Seasonal Allergic Rhinitis
Interventions: DRUG: Olopatadine HCL Nasal Spray, 0.6%|DRUG: Fluticasone Propionate Nasal Spray, 50 mcg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Safety and Immunogenicity of BI 695501 Versus Humira® in Patients With Moderate to Severe Chronic Plaque Psoriasis
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: BI 695501|DRUG: Humira
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial of Fruquintinib in Patients With Advanced Non-small Cell Lung Cancer
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: Fruquintinib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Breakfast, Exercise and Metabolic Health in Healthy Men
Status: RECRUITING
Conditions: Metabolic Health|Appetitive Behavior|Energy Balance
Interventions: BEHAVIORAL: Fasted exercise|BEHAVIORAL: High protein breakfast exercise|BEHAVIORAL: High carbohydrate breakfast exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of Erector Spina Plan Block and Rhombodid Intercostal Block in Breast Surgery
Status: COMPLETED
Conditions: Postoperative Pain|Analgesia
Interventions: OTHER: Erector Spinae Plane Block|OTHER: Rhomboid Intercostal Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effect of Liraglutide Adjunct to Insulin on Glucagon Response to Hypoglycaemia in Subjects With Type 1 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 1
Interventions: DRUG: liraglutide|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Multi-modal Characterisation of Hepatocellular Carcinoma (HCC) Treated With Targeted Radionuclide Therapy (TRT): Prospective Interventional Multicentre National Cohort
Status: NOT_YET_RECRUITING
Conditions: Hepatocellular Carcinoma|Radioembolization
Interventions: OTHER: Simultaneous 18F-Choline PET-MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effectiveness of Three Different Psychotherapies for Chronic Post-Traumatic Stress Disorder
Status: COMPLETED
Conditions: Post-Traumatic Stress Disorder
Interventions: BEHAVIORAL: Interpersonal Psychotherapy|BEHAVIORAL: Prolonged Exposure Therapy|BEHAVIORAL: Relaxation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Effectiveness of Axiostat Hemostatic Dressing Material Versus Conventional Method of Hemostasis and Healing of Extraction Wounds in Patients on Oral Anti-Platelet Drugs - A Comparative Study
Status: COMPLETED
Conditions: Tooth Extraction
Interventions: DEVICE: Axiostat|DEVICE: Cotton Gauze
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Role of Protein in Regulating Ad Libitum Energy Intake in Humans
Status: COMPLETED
Conditions: Energy Balance
Interventions: DIETARY_SUPPLEMENT: Consumption of NOW Foods eggwhite protein shake|DIETARY_SUPPLEMENT: Consumption of NOW Foods maltodextrin shake
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluating the Pharmacokinetic Interactions and Safety Between AD-2111 and AD-2112
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: AD-2111|DRUG: AD-2112
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Intrapleural Administration of Bevacizumab and Camrelizumab for Malignant Pleural Effusion
Status: UNKNOWN
Conditions: Malignant Pleural Effusion
Interventions: DRUG: bevacizumab and camrelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Xylocaine to Freeze During Unpleasant Nasopharyngeal Swabs
Status: COMPLETED
Conditions: Covid19
Interventions: DRUG: Xylocaine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Zotarolimus-Versus Sirolimus-Versus PacliTaxel-Eluting Stent for Acute Myocardial Infarction Patients
Status: TERMINATED
Conditions: Myocardial Infarction
Interventions: DEVICE: Endeavor, Medtronic|DEVICE: Cypher, Cordis|DEVICE: Taxus Liberte, Boston Scientific
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Randomized Phase II Trial of Chemoembolization and Sorafenib
Status: WITHDRAWN
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: conventional TACE in combination with sorafenib, administered on a continuous schedule|DRUG: conventional TACE in combination with sorafenib, administered on a sequential schedule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Closed Loop Neural Activity Triggered Stroke Rehabilitation Device
Status: RECRUITING
Conditions: Stroke
Interventions: DEVICE: Functional Electric Stimulation (FES)|BEHAVIORAL: Behavioral Assessments|OTHER: Magnetic Resonance Imaging|OTHER: EEG|OTHER: RecoveriX|OTHER: Delay|DEVICE: BCI-FES
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessing the Efficacy of Clomiphene Citrate in Patients With Azoospermia and Hypoandrogenism
Status: WITHDRAWN
Conditions: Non Obstructive Azoospermia|Hypogonadism
Interventions: DRUG: Clomiphene|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dose-response Relationship Study of S42909 on Leg Ulcer Healing
Status: COMPLETED
Conditions: Venous Leg Ulcer
Interventions: DRUG: S42909 100 mg|DRUG: S42909 200 mg|DRUG: S42909 400 mg|DRUG: S42909 800 mg|DRUG: S42909 1200 mg|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess Efficacy of New Malaria Vaccine Candidates AdCh63 AMA1, MVA AMA1, AdCh63 MSP1, MVA MSP1, AdCh63 ME-TRAP & MVA ME-TRAP
Status: COMPLETED
Conditions: Malaria
Interventions: BIOLOGICAL: AdCh63 MSP1, MVA MSP1, challenge|BIOLOGICAL: AdCh63 AMA1, MVA AMA1, challenge|BIOLOGICAL: AdCh63 AMA1, AdCh63 MSP1, MVA AMA1, MVA MSP1, challenge|BIOLOGICAL: AdCh63 MSP1, AdCh63 ME-TRAP, MVA MSP1, MVA ME-TRAP, challenge|BIOLOGICAL: Sporozoite challenge
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Chemoradiotherapy With or Without Atezolizumab in Treating Patients With Localized Muscle Invasive Bladder Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Bladder Urothelial Carcinoma|Muscle Invasive Bladder Carcinoma|Stage II Bladder Cancer AJCC v8|Stage IIIA Bladder Cancer AJCC v8
Interventions: DRUG: Atezolizumab|PROCEDURE: Biopsy of Bladder|DRUG: Cisplatin|PROCEDURE: Computed Tomography|PROCEDURE: Cystoscopy|DRUG: Fluorouracil|DRUG: Gemcitabine|PROCEDURE: Magnetic Resonance Imaging|DRUG: Mitomycin|OTHER: Quality-of-Life Assessment|RADIATION: Radiation Therapy|OTHER: Survey Administration|PROCEDURE: Transurethral Resection of Bladder Tumor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ofatumumab Added to Fludarabine-Cyclophosphamide vs Fludarabine-Cyclophosphamide Combination in Relapsed Subjects With Chronic Lymphocytic Leukemia
Status: COMPLETED
Conditions: Leukaemia, Lymphocytic, Chronic
Interventions: DRUG: OFC Infusion|DRUG: FC infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Effectiveness of the PXL-Platinum 330 System
Status: UNKNOWN
Conditions: Corneal Ectasia|Keratoconus|Pellucid Marginal Corneal Degeneration
Interventions: COMBINATION_PRODUCT: PXL-330 Platinum device for crosslinking with Peschke riboflavin solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Peri-implant Marginal Bone and Soft Tissue Conditions Around Single Laser-Lok Implants Placed in Regenerated Extraction Sockets and in Native Bone: A 2-years Results of RCT
Status: COMPLETED
Conditions: Partially Edentulous Maxilla, Partially Edentulous Mandible
Interventions: DEVICE: dental implants
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of Oral GSK4172239D Compared With Placebo in Sickle Cell Disease Participants Aged 18 to 50 Years
Status: RECRUITING
Conditions: Hematologic Diseases|Anaemia, Sickle Cell
Interventions: DRUG: GSK4172239D|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Semaglutide to Reduce Atrial Fibrillation Burden
Status: SUSPENDED
Conditions: Atrial Fibrillation|Obesity|Overweight
Interventions: DRUG: Semaglutide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: FDA Phase IV - Commitment - Retinal Function Study
Status: COMPLETED
Conditions: Safety
Interventions: DRUG: Sildenafil|DRUG: Placebo|DRUG: Vardenafil (Levitra, BAY38-9456)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Long-Term Safety of Hydrocodone Bitartrate Extended-Release Tablets (CEP-33237) in Patients Who Require Opioid Treatment for an Extended Period of Time
Status: COMPLETED
Conditions: Chronic Pain
Interventions: DRUG: Hydrocodone ER
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Montelukast in Patients With Chronic Cough and Bronchial Hyperreactivity
Status: COMPLETED
Conditions: Cough|Bronchial Hyperreactivity
Interventions: DRUG: montelukast|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Observation of Recombinant Human Growth Hormone Injection Assisted IVF-ET in the Treatment of PCOS
Status: UNKNOWN
Conditions: Polycystic Ovary Syndrome
Interventions: DRUG: Conventional controlled ovarian stimulation proctol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Kinesio Taping on Edema Control and Wrist Functions in Conservatively Followed Distal Radius Fractures.
Status: COMPLETED
Conditions: Distal Radius Fracture
Interventions: OTHER: kinesiotaping|OTHER: exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Lens Extraction in Patients With Pseudoexfoliation Glaucoma
Status: COMPLETED
Conditions: Pseudoexfoliation Glaucoma|Intraocular Pressure
Interventions: PROCEDURE: PHACOEMULSIFICATION|DRUG: MEDICAL GLAUCOMA TREATMENT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Efficacy of Etelcalcetide in Hemodialysis Patients With Secondary Hyperparathyroidism
Status: COMPLETED
Conditions: Secondary Hyperparathyroidism
Interventions: DRUG: Etelcalcetide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Selective Block of the Axillary Nerve in Postoperative Pain Management
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: DRUG: ropivacaine|DRUG: Sodium chloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of Acupoint Application in Improving the Sequelae of Pelvic Inflammatory Disease and Chronic Pelvic Pain
Status: RECRUITING
Conditions: Pelvic Inflammatory Disease|Chronic Pelvic Pain Syndrome
Interventions: DRUG: Improved warm meridians and relieve pain plaster|DRUG: Traditional warm meridians and relieve pain plaster|DRUG: Placebo plaster
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Liraglutide and a Calorie Restricted Diet Augments Weight Loss and Decreases Risk of Type 2 Diabetes and CVD.
Status: COMPLETED
Conditions: Pre-diabetes|Older Adults
Interventions: DRUG: liraglutide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison Between Bupivacaine-Dexmedetomidine Versus Bupivacaine-Dexamethasone in Pericapsular Nerve Group (PENG) Block
Status: RECRUITING
Conditions: Hip Fractures|Post Operative Pain
Interventions: DRUG: Pericapsular Nerve Group (PENG) Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gait and Balance in Thoracolumbar Spinal Deformity
Status: UNKNOWN
Conditions: Spinal Curvatures
Interventions: PROCEDURE: Surgical intervention|OTHER: None (Asymptomatic group)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Circulation and Oxygenation Changes of Deep Tissue Respond on LLLT
Status: UNKNOWN
Conditions: Low Level Light/Laser Therapy|Near Infrared Spectroscopy
Interventions: PROCEDURE: Low-Level Laser Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Kinesiotaping Applied to the Thumb in Rheumatoid Hand
Status: COMPLETED
Conditions: Rheumatoid Arthritis|Kinesiotape|Hand Deformity
Interventions: OTHER: Kinesiotaping|OTHER: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Erector Spinae Block Versus Local Field Block in Lumbar Spine Surgeries
Status: RECRUITING
Conditions: Postoperative Pain
Interventions: PROCEDURE: Erector spinae plane block|PROCEDURE: local field block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Ketoconazole on Regorafenib (BAY73-4506) Pharmacokinetics
Status: COMPLETED
Conditions: Pharmacokinetics
Interventions: DRUG: Regorafenib (BAY73-4506); Regorafenib (BAY73-4506) plus ketoconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Laparoscopic Versus Open Repair of Bilateral Primary Inguinal Hernia
Status: COMPLETED
Conditions: Bilateral Inguinal Hernia|Postoperative Complications
Interventions: PROCEDURE: Bilateral TAPP Repair|PROCEDURE: Open PP Repair|PROCEDURE: Bilateral Lichtenstein Repair
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Predictive Modeling to Improve Operating Room Scheduling Efficiency
Status: COMPLETED
Conditions: Operating Room Scheduling
Interventions: OTHER: Scheduling using historical means|OTHER: Scheduling using regression modeling system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Ropivacaine 0.75% Versus Levobupivacaine 0.5% for Conversion of Labour Epidural
Status: WITHDRAWN
Conditions: Caesarean Section
Interventions: DRUG: 0.5% levobupivacaine|DRUG: 0.75% Ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Association of Obesity and Cardiovascular Outcomes in Patients With Implantable Cardioverter-defibrillator (ICD)
Status: RECRUITING
Conditions: Implantable Defibrillator User|Arrhythmias, Cardiac|Obesity|Cardiovascular Morbidity
Interventions: DEVICE: ICD insertion
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Long-term Evaluation of Single-piece ACrysof IOL Implantation on Development of Posterior Capsule Opacification
Status: COMPLETED
Conditions: Posterior Capsule Opacification After Phacoemulsification and IOL Implantation
Interventions: PROCEDURE: Cataract surgery with IOL implantation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phase II Study of Docetaxel + ZD1839 in Elderly Patients With Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: docetaxel (Taxotere®)|DRUG: ZD1839
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Pharmacokinetic Study of Lurbinectedin in Patients With Advanced Solid Tumors and Varying Degrees of Hepatic Impairment
Status: RECRUITING
Conditions: Advanced Solid Tumor|Hepatic Impairment
Interventions: DRUG: Lurbinectedin|DRUG: Lurbinectedin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability Study of Daily Dosing Rimegepant in Episodic Migraine Prevention
Status: COMPLETED
Conditions: Migraine|Episodic Migraine|Phonophobia|Photophobia
Interventions: DRUG: Rimegepant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial Using Irreversible Electroporation for the Treatment of Liver Cancers
Status: COMPLETED
Conditions: Hepatocellular Carcinoma|Metastatic Liver Cancers
Interventions: DEVICE: Irreversible Electroporation (IRE) System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Manual Lymphatic Drainage Versus Standard Treatment for the Prevention of Breast Cancer-related Lymphoedema in Patients Who Undergo Axillary Node Clearance
Status: COMPLETED
Conditions: Breast Cancer Related Lymphoedema
Interventions: COMBINATION_PRODUCT: Decongestive lymphatic therapy (DLT)|OTHER: Standard Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of the Pharmacokinetics/Pharmacodynamics and Safety/Tolerability of IN-C005 and IN-A001 in Healthy Caucasians
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: IN-C005 X mg|DRUG: IN-A001 Y mg|DRUG: IN-C005 Y mg|DRUG: IN-C005 Z mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Memantine Hydrochloride (Namenda®) for Cognitive and Behavioral Impairment in Adults With Autism Spectrum Disorders
Status: COMPLETED
Conditions: Autism Spectrum Disorders
Interventions: DRUG: Memantine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Estradiol, Progesterone and Endometrial Thickness in Frozen Euploid Embryo Transfer
Status: COMPLETED
Conditions: Infertility|Preimplantation Genetic Diagnosis/Screening|Miscarriage
Interventions: OTHER: Estradiol level|OTHER: Progesterone level|OTHER: Endometrial thickness
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: GTI-2040, Docetaxel, and Prednisone in Treating Patients With Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: BIOLOGICAL: GTI-2040|DRUG: docetaxel|DRUG: prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of the Efficacy of the Transnasal Sphenopalatine Ganglion Block in the Treatment of Chronic Daily Headache in Children and Adolescents.
Status: NOT_YET_RECRUITING
Conditions: Chronic Daily Headache|Post-Traumatic Headache
Interventions: OTHER: Sphenopalatine ganglion block with 0.5% bupivacaine|OTHER: Sphenopalatine ganglion block with saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: NA-831, Atazanavir and Dexamethasone Combination Therapy for the Treatment of COVID-19 Infection
Status: UNKNOWN
Conditions: Coronavirus Infection|Severe Acute Respiratory Infection|Severe Acute Respiratory Syndrome Coronavirus 2
Interventions: DRUG: Drug: NA-831|COMBINATION_PRODUCT: NA-831 and Atazanavir|COMBINATION_PRODUCT: NA-831and Dexamethasone|COMBINATION_PRODUCT: Atazanavir and Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Acute Effects Of Donepezil On Brain Perfusion And Memory In Subjects With Cognitive Impairment And Mild Alzheimer's Disease
Status: TERMINATED
Conditions: Alzheimer's Disease
Interventions: DRUG: Donepezil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study to Characterize the Local Duration of Exposure From FX006 in Patients With Osteoarthritis of the Knee
Status: COMPLETED
Conditions: Osteoarthritis of the Knee
Interventions: DRUG: FX006 10 mg|DRUG: FX006 40 mg|DRUG: TCA IR 40 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Deep Neck Flexor Exercises Versus Myofascial Release of Suboccipital Muscles in Chronic Tension-type Headache
Status: NOT_YET_RECRUITING
Conditions: Chronic Tension-Type Headache
Interventions: OTHER: Suboccipital Myofascial Release(MFR) with sham Deep Neck Flexor(DNF)exercise|OTHER: Deep Neck Flexor(DNF)exercise with sham Suboccipital Myofascial Release(MFR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PG2 Phase I/II Clinical Study Intravenously Administered in Patients With Advanced Malignancy
Status: COMPLETED
Conditions: Neoplasm Metastasis|Neoplasm Recurrence
Interventions: DRUG: PG2
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low-dose Contrast Media for Low-kVp Abdomen CT
Status: NOT_YET_RECRUITING
Conditions: Appendicitis Acute
Interventions: DIAGNOSTIC_TEST: Weight-adjusted low-dose contrast media paired with low-radiation dose abdomen CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Pilot Evaluation of an Experimental BLI4600 Formulation for Bowel Preparation in Adult Patients Undergoing Colonoscopy
Status: COMPLETED
Conditions: Bowel Preparation for Colonoscopy
Interventions: DRUG: BLI4600 bowel preparation|DRUG: PEG based bowel preparation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Influence of the Vitamine E Coated Dialyzer on Inflammation and Anemia
Status: COMPLETED
Conditions: End Stage Renal Disease|Inflammation
Interventions: DEVICE: VIE high flux dialyzer|DEVICE: Leoceed H high flux dialyzer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study for Magnetic Stimulation of the Posterior Tibial Nerve in Overactive Bladder
Status: COMPLETED
Conditions: Overactive Bladder
Interventions: DEVICE: EMKinetics non-invasive Magnetic neurostimulator
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study of Adjunctive Aspirin for the Treatment of HIV Negative Adults With Tuberculous Meningitis
Status: COMPLETED
Conditions: Tuberculous Meningitis
Interventions: DRUG: 81mg aspirin|DRUG: 1000mg aspirin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Efficacy and Safety of VK2809 for 52 Weeks in Subjects With Biopsy Proven NASH
Status: COMPLETED
Conditions: NASH - Nonalcoholic Steatohepatitis
Interventions: DRUG: VK2809|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I Study Of The Safety, Tolerability, Pharmacokinetics And Pharmacodynamics Of Multiple Intravenously Administered Doses Of PF-04236921 In Patients With Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Placebo|DRUG: dose level 1|DRUG: dose level 2|DRUG: dose level 3|DRUG: dose level 4
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Safety and Efficacy of IBI188 With Azacitidine in Subjects With Newly Diagnosed Higher Risk MDS
Status: SUSPENDED
Conditions: Myelodysplastic Syndromes
Interventions: DRUG: IBI188+azacitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Value of the LightCycler® SeptiFast Test MGRADE for the Pathogen Detection in Neutropenic Hematological Patients
Status: COMPLETED
Conditions: Hematologic Diseases|Neutropenia|Febrile Neutropenia|Sepsis
Interventions: OTHER: Detection of microbial DNA in blood by SeptiFast Test|OTHER: Pathogen detection by blood culture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Platelet-Rich Plasma Therapy for Patellar Tendinopathy
Status: COMPLETED
Conditions: Patellar Tendinitis
Interventions: BIOLOGICAL: PRP|PROCEDURE: Dry Needling|PROCEDURE: Dry Needling - Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ONC206 for Treatment of Newly Diagnosed, Recurrent Diffuse Midline Gliomas, and Other Recurrent Malignant CNS Tumors
Status: RECRUITING
Conditions: Diffuse Midline Glioma (DMG)|Glioblastoma|Recurrent Ependymoma|Recurrent Malignant Central Nervous System Neoplasm|Spinal Cord Glioma|World Health Organization (WHO) Grade III Glioma|CNS Tumor|Central Nervous System Tumor
Interventions: DRUG: ONC206|RADIATION: Standard of Care Radiation Therapy|PROCEDURE: Optional Proton (1H) MR spectroscopy (MRS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: VELCADE® Plus Rituximab in Non Hodgkin's Follicular Lymphoma
Status: COMPLETED
Conditions: Non Hodgkin's Follicular Lymphoma
Interventions: DRUG: Bortezomib (VELCADE)|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of IV NTG for CD After Second Stage Arrest for the Prevention of Uterine Extension
Status: COMPLETED
Conditions: Prolonged Second Stage of Labor
Interventions: DRUG: intravenous nitroglycerin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Controlled Acute Hypoxia Study Comparing Pulse Oximetry to Arterial Blood Samples During Motion
Status: COMPLETED
Conditions: Healthy|Hypoxia
Interventions: DEVICE: Arterial line|DEVICE: Motion
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Short-course High-dose Prednisone and Dexamethasone in Children With ITP
Status: RECRUITING
Conditions: Immune Thrombocytopenia|Glucocorticoids|Child, Only
Interventions: DRUG: Prednisone|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Evaluation to Assess the Clinical and Economic Impact of Pfizer's Pain Management Program (painPREMIER) in the Treatment of Low Back Pain, in an Occupational Health Care Setting in Finland
Status: TERMINATED
Conditions: Back Pain
Interventions: OTHER: painPREMIER cohort|OTHER: Control cohort
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Magnetic Resonance Imaging (MRI) Hysterosalpingography Versus Radiographic Hysterosalpingography in Female Infertility
Status: COMPLETED
Conditions: Female Infertility
Interventions: RADIATION: Radiographic hysterosalpingography|RADIATION: Magnetic resonance imaging hysterosalpingography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Ehealth: Second Life Impacts Diabetes Education & Self-Management
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: BEHAVIORAL: eHealth program in the Virtual Environment (VE) platform Second Life
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Berberine for Endothelial Function and Intestinal Microflora in Patients With Coronary Artery Disease
Status: UNKNOWN
Conditions: Stable Coronary Artery Disease|Percutaneous Coronary Intervention
Interventions: DRUG: Berberine|DRUG: Aspirin|DRUG: Clopidogrel|DRUG: Statin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare Nivolumab Administered Subcutaneously vs Intravenous in Melanoma Participants Following Complete Resection
Status: COMPLETED
Conditions: Melanoma
Interventions: BIOLOGICAL: Nivolumab/rHuPH20|BIOLOGICAL: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Clinical Trial of Enamel Matrix Derivative: Radiographic Analysis
Status: COMPLETED
Conditions: Chronic Periodontitis
Interventions: DRUG: enamel matrix derivative|PROCEDURE: Open flap debridement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Single-blind, Placebo-controlled, Outpatient Trial to Assess the Effects of Single Oral Tablet Dose of OPC-214870
Status: COMPLETED
Conditions: Epilepsy
Interventions: DRUG: OPC-214870|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Multicenter Prospective Study on the Changes of Sexual Function Following Treatment With Alfuzosin (Xatral XL®) in Patients With Benign Prostate Hypertrophy
Status: COMPLETED
Conditions: BPH/LUTS/Sexual Functions
Interventions: DRUG: Alfuzosin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hemodynamics, Salt Sensitivity and Body Composition in Patients With Morbid Obesity
Status: COMPLETED
Conditions: Obesity|Hypertension
Interventions: OTHER: 24-hour blood pressure|OTHER: Echocardiography|OTHER: Inert gas rebreathing|RADIATION: Dexa-scan|RADIATION: Plasma volume|RADIATION: Glomerular filtration rate (GFR)|OTHER: Blood samples|OTHER: Urine analyses|DIETARY_SUPPLEMENT: Diets with low and high sodium content
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Patient Automated Text Hovering for IBD
Status: COMPLETED
Conditions: Inflammatory Bowel Diseases|Crohn Disease|Ulcerative Colitis
Interventions: BEHAVIORAL: Control|BEHAVIORAL: Text-based Clinical Hovering
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: LED Photomodulation for Prevention of Post-Radiation Treatment Dermatitis
Status: COMPLETED
Conditions: Radiation Dermatitis
Interventions: DEVICE: Gentlewaves Select™ handheld high energy LED array|RADIATION: Radiation|RADIATION: Radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: GEMOX Combined With Targeted Therapy and Immunotherapy for Patients With Advanced Cholangiocarcinoma
Status: RECRUITING
Conditions: Cholangiocarcinoma
Interventions: DRUG: GEMOX Regimen|DRUG: Lenvatinib|DRUG: Toripalimab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Impact of Obesity on Nonsurgical Periodontal Therapy
Status: UNKNOWN
Conditions: Periodontitis|Periodontal Diseases|Obesity
Interventions: DRUG: Metronidazole|DRUG: Placebo|PROCEDURE: Scaling and root planning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Single Dose Study of ALXN1101 in Healthy Volunteers
Status: COMPLETED
Conditions: Molybdenum Cofactor Deficiency (MoCD)|Rare Autosomal Recessive Disorder|Deficiency of Activity of Molybdenum-dependent Enzymes (Sulfite Oxidase [SOX], Xanthine Dehydrogenase, and Aldehyde Oxidase)
Interventions: DRUG: ALXN1101|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intravenous Immunoglobulin (IVIG, Bioven) Efficacy and Safety in Chronic Primary Immune Thrombocytopenia (ITP) in Adults
Status: RECRUITING
Conditions: Primary Immune Thrombocytopenia
Interventions: DRUG: Intravenous immunoglobulin (IVIG), 10% solution for infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A 2-week Trial Of PF-04991532 In Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: PF-04991532|DRUG: PF-04991532|DRUG: PF-04991532|DRUG: PF-0499132|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: GSK1349572 Drug Interaction Study With Fosamprenavir/Ritonavir
Status: COMPLETED
Conditions: Infections, Human Immunodeficiency Virus and Herpesviridae
Interventions: DRUG: GSK1349572|DRUG: Fosamprenavir|DRUG: Ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: XiVE® CAD/CAM Bridges (Abutment-supported/ Implant-supported)
Status: COMPLETED
Conditions: Partly Edentulous Maxilla
Interventions: DEVICE: Abutment-supported XiVE CAD/CAM bridge|DEVICE: Implant-supported XiVE CAD/CAM bridge
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PAD Combination Therapy Followed by Thal/Dex for Relapsed or Refractory Multiple Myeloma
Status: UNKNOWN
Conditions: Multiple Myeloma
Interventions: DRUG: Velcade|DRUG: Thalidomide|DRUG: Adriamycin|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Adipose Tissue Derived Stem Cells for the Treatment of Diabetic Foot Ulcers
Status: RECRUITING
Conditions: Diabetic Foot Ulcer|Diabetes Mellitus|Diabetic Foot|Diabetic Foot Infection|Diabetic Foot Ulcer Neuropathic|Foot Ulcer Due to Type 1 Diabetes Mellitus|Foot Ulcer Due to Type 2 Diabetes Mellitus|Foot Ulcer|Diabetes Complications|Chronic Diabetic Ulcer of Left Foot|Chronic Diabetic Foot Ulcer of Right Foot
Interventions: OTHER: Control; Standard-of-care management|BIOLOGICAL: Only PRP injection|BIOLOGICAL: PRP + SVF injection|BIOLOGICAL: PRP + ASCs injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Bavituximab Plus Paclitaxel and Carboplatin to Treat Breast Cancer
Status: COMPLETED
Conditions: Carcinoma Breast Stage IV
Interventions: DRUG: Bavituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transcend Auto Clinical Evaluation
Status: COMPLETED
Conditions: Obstructive Sleep Apnea
Interventions: DEVICE: Somnetics Transcend Auto|DEVICE: Respironics REMstar Auto with C-Flex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Capecitabine Plus Concomitant Radiation Therapy Followed by Durvalumab as Preoperative Treatment in Rectal Cancer
Status: RECRUITING
Conditions: RECTAL CANCER
Interventions: DRUG: Capecitabine|DRUG: Radiotherapy|DRUG: Durvalumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT