pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Setrusumab vs Bisphosphonates in Pediatric Subjects With Osteogenesis Imperfecta
Status: ACTIVE_NOT_RECRUITING
Conditions: Osteogenesis Imperfecta
Interventions: DRUG: Bisphosphonate|BIOLOGICAL: Setrusumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Pemetrexed Maintenance With or Without ADXS11-001 Immunotherapy in Patients With Human Papillomavirus Positive (HPV+), NSCLC Following First-Line Induction Chemotherapy
Status: WITHDRAWN
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: ADXS11-001|DRUG: Pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: FST-100 in the Treatment of Acute Viral Conjunctivitis
Status: COMPLETED
Conditions: Acute Viral Conjunctivitis
Interventions: DRUG: FST-100|DRUG: FST-100 Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ga-68-NODAGA-MJ9 Compared to F-18-FCH PET/CT for Prostate Cancer Patients
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DIAGNOSTIC_TEST: 1 PET/CT with F-18-FCH + 1 PET/CT with Ga-68-NODAGA-MJ9
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Using a Fan With Aromatherapy in Breathlessness Patients in Terminal Illness
Status: ENROLLING_BY_INVITATION
Conditions: Breathlessness|Aromatherapy|Fans|Terminal Illness
Interventions: BEHAVIORAL: Blow a fan to the face combine aromatherapy|BEHAVIORAL: Blow a fan to the face|BEHAVIORAL: Blow a fan to the feet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Testing the Role of Anti-fungal Therapy in Improving the Response to Therapies for Crohn's Disease
Status: NOT_YET_RECRUITING
Conditions: Crohn's Disease|Inflammatory Bowel Diseases
Interventions: DRUG: Fluconazole|DRUG: Placebo|BIOLOGICAL: IL-23 Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Foot Massage on Blood Pressure and Anxiety Levels in Pregnants With Hypertension
Status: COMPLETED
Conditions: Pre-Eclampsia|Gestational Hypertension|Chronic Hypertension With Pre-Eclampsia|Superimposed Pre-Eclampsia
Interventions: OTHER: Foot Massage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Research Study for Patients With Overactive Bladder
Status: COMPLETED
Conditions: Overactive Bladder|Urinary Incontinence
Interventions: BIOLOGICAL: botulinum toxin Type A|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Serum Biomarkers to Characterize the Effects of Therapy on Ovarian Reserve in Premenopausal Women With Early-stage Breast Cancer or BRCA Mutations
Status: RECRUITING
Conditions: Breast Cancer
Interventions: OTHER: Blood draw and questionnaires|OTHER: Blood draw and questionnaires
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Test Long-term Treatment With Spesolimab in Patients With Fistulising Crohn's Disease Who Took Part in Previous Trials
Status: TERMINATED
Conditions: Crohn Disease
Interventions: DRUG: Spesolimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of High Flow Nasal Cannula Therapy to Nasal Oxygen as a Treatment for Obstructive Sleep Apnea in Infants
Status: COMPLETED
Conditions: Obstructive Sleep Apnea
Interventions: OTHER: HFNC|OTHER: Low flow oxygen by nasal cannula
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adalimumab in Adult Japanese Subjects With Moderate to Severe Chronic Plaque Psoriasis
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: Human anti-TNF monoclonal antibody adalimumab/ up to 24 weeks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Study of Acthar® Gel (Acthar) for Amyotrophic Lateral Sclerosis (ALS)
Status: TERMINATED
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DRUG: Acthar|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Virtual Reality in Reeducation : Application to Shoulder Affections
Status: ACTIVE_NOT_RECRUITING
Conditions: Scapular Dyskinesis|Shoulder Pain
Interventions: DEVICE: Virtual reality device|OTHER: EBM rehabilitation exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Un-fractionated Heparin Versus Bivalirudin During Percutaneous Coronary Interventions (PCI) (ISAR-REACT-3)
Status: COMPLETED
Conditions: Coronary Disease|Angina Pectoris
Interventions: DRUG: Bivalirudin|DRUG: Un-fractionated heparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Growing Up Milk (GUM) Intake and Nutrient Status of Toddlers
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: Test GUM|OTHER: Standard GUM|OTHER: Cows' milk
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Combination Chemotherapy and Exisulind in Treating Patients With Extensive-Stage Small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DRUG: carboplatin|DRUG: etoposide|DRUG: exisulind
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Clinical and Bone Density Improvement After Implantation of Allogenic Mesenchymal Stem Cell From Umbilical Cord on Osteoporosis Patients
Status: UNKNOWN
Conditions: Osteoporosis
Interventions: DRUG: Mesenchymal Stem Cell
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Pharmacokinetics of HRS-1780 in Healthy Subjects and Subjects With Impaired Renal Function
Status: NOT_YET_RECRUITING
Conditions: Chronic Kidney Disease
Interventions: DRUG: HRS-1780
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Oral Microbiome as a Prognostic Tool in Oral Malignant and Premalignant Lesions and in Medication Related Osteonecrosis of the Jaw
Status: UNKNOWN
Conditions: Oral Squamous Cell Carcinoma|Medication Related Osteonecrosis of the Jaw|Oral Epithelial Dysplasia
Interventions: DIAGNOSTIC_TEST: Buccal mucosa samples for Extraction of BACTERIAL DNA
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: High-frequency vs. Low-frequency vs. Sham DMPFC-rTMS for Major Depression
Status: UNKNOWN
Conditions: Depression
Interventions: DEVICE: High-frequency rTMS|DEVICE: Low-frequency rTMS|DEVICE: Sham rTMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: DuoTrav APS Versus XALACOM® in Ocular Surface Health
Status: TERMINATED
Conditions: Open Angle Glaucoma|Ocular Hypertension
Interventions: DRUG: DuoTrav APS|DRUG: Xalacom
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Drug Resistance Molecular Biology of Apatinib Combined With EGFR-TK1 Treated for Advanced Slow-progressed Non-Small Cell Lung Cancer (NSCLC)
Status: UNKNOWN
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: Apatinib（250mg/d） combined with EGFR-TKI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Therapy With Pegylated Interferon and Ribavirin in Patients With Chronic Hepatitis C Genotype 2 or 3 Infection Who Previously Have Relapsed After Therapy With Pegylated Interferon and Ribavirin
Status: TERMINATED
Conditions: Chronic Hepatitis C
Interventions: DRUG: Pegylated interferon alfa-2a and ribavirin|DRUG: Pegylated interferon alfa-2a and ribavirin|DRUG: Pegylated interferon alfa-2a and ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chen-style Tai Chi in Pulmonary Rehabilitation for Chronic Obstructive Pulmonary Disease
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: BEHAVIORAL: Tai chi|BEHAVIORAL: Conventional exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Long-term Safety and Efficacy Study of Lebrikizumab (LY3650150) in Participants With Moderate-to-Severe Atopic Dermatitis (ADjoin)
Status: ACTIVE_NOT_RECRUITING
Conditions: Atopic Dermatitis
Interventions: BIOLOGICAL: Lebrikizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: "Phase I / II Study on Infusion of Natural Killer Cells After Haploidentical Transplantation in Pediatric Patients"
Status: UNKNOWN
Conditions: High-risk Leukemias
Interventions: BIOLOGICAL: NK cells stimulated ex vivo with IL-15|BIOLOGICAL: Alloreactive NK cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: International Penile Advanced Cancer Trial (International Rare Cancers Initiative Study)
Status: RECRUITING
Conditions: Squamous Cell Carcinoma of the Penis, Usual Type
Interventions: PROCEDURE: ILND - Inguinal Lymph Node Dissection|DRUG: Paclitaxel|DRUG: Ifosfamide|DRUG: Cisplatin|RADIATION: Intensity modulated radiation treatment (IMRT)|PROCEDURE: Prophylactic PLND - pelvic lymph node dissection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study on the Prevention of the Vascular RISK Related to Atrial Fibrillation After Intracranial Hemorrhage by Closing the Left Auricle
Status: COMPLETED
Conditions: Atrial Fibrillation|Intracranial Hemorrhages
Interventions: DIAGNOSTIC_TEST: Compare the risk of a vascular event
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: The Effects of RFA in Combination With Second-line Chemotherapy and Bevacizumab on Unresectable CRLM
Status: UNKNOWN
Conditions: Colorectal Neoplasms Malignant
Interventions: COMBINATION_PRODUCT: RFA, bevacizumab and second-line chemotherapy|DRUG: Bevacizumab and second-line chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Limb RIPC in Patients Undergoing Lung Lobectomy. Study of Oxidative Lung Damage
Status: COMPLETED
Conditions: Acute Lung Injury
Interventions: PROCEDURE: remote ischemic preconditioning (RIPC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Behavioral and Neural Representations of Subjective Effort Cost
Status: RECRUITING
Conditions: Fatigue
Interventions: BEHAVIORAL: Cognitive Fatigue|BEHAVIORAL: Physical Fatigue|BEHAVIORAL: Rewarding Stimuli
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effectiveness of Breastfeeding Techniques to Improve Latching and Prevention of Nipplesoreness
Status: NOT_YET_RECRUITING
Conditions: Breastfeeding
Interventions: BEHAVIORAL: Educational breastfeeding traning session
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Monoclonal Antibody Followed by Bone Marrow Transplantation in Treating Patients With Acute Myelogenous Leukemia in Remission or First Relapse
Status: COMPLETED
Conditions: Leukemia
Interventions: DRUG: busulfan|DRUG: cyclophosphamide|DRUG: methotrexate|PROCEDURE: allogeneic bone marrow transplantation|RADIATION: radioimmunotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Coagulation Activity and Thrombogenesis in Patients With Atrial Fibrillation
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: PROCEDURE: circumferential ablation|DEVICE: SVT ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Epidural Clonidine for Lumbosacral Radiculopathy
Status: TERMINATED
Conditions: Lumbar and Other Intervertebral Disc Disorders With Radiculopathy
Interventions: DRUG: Clonidine|DRUG: Triamcinolone hexacetonide|DRUG: Lidocaine HCl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of RPL554 on Top of Standard COPD Reliever Medications
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Salbutamol|DRUG: Ipratropium|DRUG: RPL554|DRUG: Salbutamol matched placebo|DRUG: Ipratropium matched placebo|DRUG: RPL554 matched placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Heparin 100U/L for Prevention of PVC Complications
Status: COMPLETED
Conditions: Peripheral Venous Catheter Complications|Occlusion|Phlebitis|Ecchymosis
Interventions: OTHER: heparin 100U/L flushes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Brief Intervention Based on the Theory of Planned Behavior to Reduce Alcohol Consumption in University Students
Status: COMPLETED
Conditions: Alcohol; Harmful Use
Interventions: BEHAVIORAL: Brief Intervention Based on the Theory of Planned Behavior to Reduce Alcohol Consumption in University Students
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Intravitreal Long Acting Gas in the Prevention of Early Postoperative Vitreous Hemorrhage in Diabetic Vitrectomy
Status: COMPLETED
Conditions: Diabetes Mellitus|Diabetic Retinopathy|Vitreous Hemorrhage
Interventions: PROCEDURE: Intravitreal long acting gas (10% C3F8)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Aerobic Training in Diabetic vs Non-Diabetic Post-Stroke Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Stroke
Interventions: DIAGNOSTIC_TEST: Aerobic Exercise in diabetic post-stroke patients|OTHER: Aerobic Exercise in Non diabetic post-stroke patients
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Ipilimumab With Nivolumab for Molecular-selected Patients With Castration-resistant Prostate Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostatic Neoplasms, Castration-Resistant
Interventions: BIOLOGICAL: Ipilimumab|BIOLOGICAL: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Outcome of Two Surgical Methods for IOLImplantation in Eyes With Pseudoexfoliation Syndrome
Status: RECRUITING
Conditions: Age Related Cataracts|Pseudoexfoliation Syndrome
Interventions: PROCEDURE: Phakoemulsification|DEVICE: Ziemer Z8 Femtolaser|DEVICE: Kowa Avansee Preset
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sentinel and/or Axillary Lymph Node Biopsy With or Without Axillary Reverse Mapping in Reducing Incidence and Severity of Arm Lymphedema in Stage 0-2 Patients.
Status: TERMINATED
Conditions: Lymphedema|Recurrent Breast Cancer|Stage IA Breast Cancer|Stage IB Breast Cancer|Stage II Breast Cancer
Interventions: RADIATION: technetium Tc 99m sulfur colloid|DRUG: methylene blue|DRUG: indocyanine green solution|PROCEDURE: sentinel lymph node biopsy|PROCEDURE: axillary lymph node biopsy|PROCEDURE: bioimpedance spectroscopy|PROCEDURE: quality-of-life assessment|OTHER: lymphedema management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Cognitive Training in Children With Attention Deficit Hyperactivity Disorder (ADHD)
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder (ADHD)
Interventions: BEHAVIORAL: Cogmed|BEHAVIORAL: Presco
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cervical Cytology DNA Methylation for Cervical Cancer Screening
Status: NOT_YET_RECRUITING
Conditions: Cervical Cancer|DNA Methylation|Cytology|Human Papillomavirus Infection|Cervical Intraepithelial Neoplasia|Cancer Screening
Interventions: DIAGNOSTIC_TEST: human PAX1 and JAM3 gene methylation assays (PAX1m/JAM3m)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Preemptive Paracetamol for Postoperative Pain
Status: UNKNOWN
Conditions: Pain|Surgical Wound
Interventions: DRUG: Intravenous paracetamol|DRUG: Intravenous saline 0.9%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Assessing the Safety and Efficacy of Multiple Intravitreal KH902 in Patients With CNV Due to AMD
Status: COMPLETED
Conditions: Neovascular Age-related Macular Degeneration
Interventions: BIOLOGICAL: Intravitreal injection of KH902
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Controlled Trial of Valproate Versus Risperidone in Young Children With Bipolar Disorder
Status: COMPLETED
Conditions: Bipolar Disorder
Interventions: DRUG: Risperidone|DRUG: Valproic Acid|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Usefulness of Metoclopramide to Improve Endoscopic Visualization in Upper Gastrointestinal Bleeding
Status: RECRUITING
Conditions: Upper Gastrointestinal Bleeding
Interventions: DRUG: Metoclopramide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: DIAGNOSTIC
Clinical trial: QLESP Block in Hip Surgery
Status: WITHDRAWN
Conditions: Postoperative Pain
Interventions: PROCEDURE: transmuscular quadratus lumborum and modified erector spinae plane (QLESP) block|PROCEDURE: suprainguinal fascia iliaca block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Image-Guided Functional Lung Avoidance Thoracic Radiotherapy for Lung Cancer: A Single-Blind Randomized Trial
Status: UNKNOWN
Conditions: Small Cell Lung Cancer, Limited Stage|Stage III Non-small Cell Lung Cancer
Interventions: RADIATION: Functional Lung Avoidance Thoracic Radiotherapy|RADIATION: Standard Thoracic Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Pharmacokinetic Exposure of 2 Formulations of Apremilast in Healthy Adults
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Apremilast IR|DRUG: Apremilast XL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Postcoital Testing Study of the SILCS Diaphragm Used With 3% N-9 Gel, ContraGel, or No Gel
Status: COMPLETED
Conditions: Contraception
Interventions: OTHER: SILCS diaphragm used with ContraGel|OTHER: SILCS diaphragm used with 3% Nonoxynol-9|OTHER: SILCS diaphragm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Guanfacine for PONV and Pain After Sinus Surgery
Status: COMPLETED
Conditions: Postoperative Nausea and Vomiting|Pain, Postoperative
Interventions: DRUG: Guanfacine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Half-Dose Radiopharmaceutical in Wide Beam Reconstruction
Status: TERMINATED
Conditions: Myocardial Infarction|Ischemic Heart Disease
Interventions: DRUG: Half-dose of the Tc99-m sestamibi (Cardiolite)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Vitamin D Supplement Study for Adolescents
Status: COMPLETED
Conditions: Vitamin D Deficiency|Overweight|Obesity
Interventions: DIETARY_SUPPLEMENT: 2000 IU Vitamin D3 daily supplement|DIETARY_SUPPLEMENT: 400 IU Vitamin D3 supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety and Intraocular Pressure (IOP) Lowering Effect of AL-59412C
Status: TERMINATED
Conditions: Open-angle Glaucoma|Ocular Hypertension
Interventions: DRUG: AL-59412C injectable solution|DRUG: Travoprost injectable solution|DRUG: AL-59412C Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating Safety and Efficacy of Mesenchymal Stem Cells From Umbilical Cord
Status: UNKNOWN
Conditions: Umbilical Cord Bleeding|Knee Osteoarthritis
Interventions: DRUG: mesenchymal stem cells from umbilical cord
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intravenous Iron Isomaltoside 1000 (Monofer®) Compared With Oral Iron in the Treatment of Postgastrectomy Anemia: An Open-label Randomized Controlled Trial
Status: UNKNOWN
Conditions: Post Gastrectomy Anemia
Interventions: DRUG: iron isomaltoside (Monofer) intravenous infusion|DRUG: Ferrous sulfate(Feroba-YOU) per oral
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Compare Safety and the General Imaging Pattern of Cyclotron Produced Technetium vs. Generator Produced Technetium in Patients With Thyroid Cancer
Status: COMPLETED
Conditions: Thyroid Neoplasms
Interventions: DRUG: CPERT|DRUG: GPERT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: First Line Study of Tamibarotene in Combination for Advanced Non-Small Cell Lung Cancer
Status: TERMINATED
Conditions: Stage IIIB Non-small Cell Lung Cancer With Pleural Effusion|Stage IV Non-small Cell Lung Cancer
Interventions: DRUG: Tamibarotene|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy Testing of Hibiscus Sabdariffa Extract and Collagen Products
Status: COMPLETED
Conditions: Skin Condition
Interventions: DIETARY_SUPPLEMENT: Placebo sachet|DIETARY_SUPPLEMENT: Hibiscus sabdariffa extract and collagen products
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: nHFOV Versus nCPAP in Transient Tachypnea of the Newborn
Status: COMPLETED
Conditions: Transient Tachypnea of the Newborn
Interventions: DEVICE: nHFOV|DEVICE: nCPAP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study Exploring the Efficacy and Safety of Herbal Medicine on Korean Obese Women With Metabolic Syndrome Risk Factors - Double Blinded, Randomized, Multicenter, Placebo Controlled Clinical Trial -
Status: COMPLETED
Conditions: Metabolic Syndrome|Obesity
Interventions: DRUG: Daesiho-tang|DRUG: Chowiseungcheng-tang|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nonmyeloablative Stem Cell Transplant in Children With Sickle Cell Disease and a Major ABO-Incompatible Matched Sibling Donor
Status: RECRUITING
Conditions: Sickle Cell Disease|Stem Cell Transplant Complications|Red Blood Cell Disorder|Pure Red Cell Aplasia
Interventions: DRUG: Alemtuzumab|RADIATION: Total Body Irradiation|DRUG: Sirolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Sugar-free Products With Added Sweeteners on Glycemic Responses
Status: COMPLETED
Conditions: Potential Abnormality of Glucose Tolerance|Appetitive Behavior
Interventions: OTHER: Glucose as reference food|OTHER: White bread as reference food|OTHER: White bread with apricot jam|OTHER: Cereal bar with cranberries|OTHER: Cocoa drink
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Standard Care With LLLT & Myofascial Release Versus Standard Care Alone in Pregnant Women With Temporomandibular Disorder
Status: COMPLETED
Conditions: Temporomandibular Disorder
Interventions: OTHER: Low Level laser therapy|OTHER: Myofascial release|OTHER: Standard care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fenretinide in Treating Patients Who Have Undergone Surgery for Bladder Cancer
Status: COMPLETED
Conditions: Bladder Cancer
Interventions: DRUG: Fenretinide|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Tailored Home-Based Exercise Program for Multiple Chronic Conditions
Status: COMPLETED
Conditions: Cancer|Hypertension|Diabetes
Interventions: OTHER: Tailored Technology-Enhance Home-based exercise program (iHBE)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Phase 1 Study Of Talazoparib, PARP Inhibitor, In Japanese Patients With Advanced Solid Tumors
Status: COMPLETED
Conditions: Neoplasms|Breast Neoplasms
Interventions: DRUG: talazoparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Abiraterone Acetate or Enzalutamide, Atezolizumab, GnRH Analog and Radiation Therapy in Men With Newly Diagnosed Hormone-sensitive Prostate Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Prostate Cancer
Interventions: DRUG: Atezolizumab|DRUG: Abiraterone|DRUG: Prednisone|DRUG: GnRH analog|RADIATION: Stereotactic Body Radiotherapy (SBRT)|DRUG: Enzalutamide|OTHER: Follow up
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Respiratory Muscles and Work of Breathing in Children
Status: RECRUITING
Conditions: Neuromuscular Diseases|Congenital Diaphragmatic Hernia|Lung Diseases|Cardiac Diseases|Scoliosis|Diaphragmatic Impairment|Respiratory Muscle Impairment
Interventions: OTHER: Esogastric pressure measurement
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Multiple Dose Study of Safety and Pharmacokinetics of MEDI0618 in Healthy Volunteers
Status: COMPLETED
Conditions: Chronic Pain
Interventions: DRUG: MEDI0618|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Characterization of Patients With Uncommon Presentations and/or Uncommon Diseases Associated With the Cardiovascular System
Status: RECRUITING
Conditions: Cardiomyopathy|Li-Fraumeni Syndrome|Parkinson's Disease|Atherosclerosis|Cardiovascular Capacity
Interventions: DEVICE: NSR IDE-MRI: Research pulse sequences
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Practice Change for Patients With Severe Chronic, Clinically Unexplained Gastrointestinal Symptoms
Status: RECRUITING
Conditions: Gastrointestinal Diseases|Irritable Bowel Syndrome
Interventions: BEHAVIORAL: a)standardised dietician supervised intervention, b) exercise intervention, c) internet delivered cognitive behavior therapy or d) nothing|BEHAVIORAL: a) consultant-led outpatient clinic or b) a integrated care clinic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: NEXUS™ Aortic Arch Stent Graft System First In Man Study
Status: COMPLETED
Conditions: Thoracic Aortic Arch Disease|Thoracic Aortic Aneurysm
Interventions: DEVICE: Stent Graft Placement (Nexus)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of CPAP Treatment on Blood Pressure of Resistant Hypertension Patients With Obstructive Sleep Apnea Syndrome
Status: COMPLETED
Conditions: Obstructive Sleep Apnea Syndrome|Resistant Hypertension
Interventions: PROCEDURE: Continuous positive airway pressure treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CSD201002: Study to Assess Nicotine Uptake From P10 Nicotine Pouches
Status: COMPLETED
Conditions: Smoking|Tobacco Use
Interventions: OTHER: Product A|OTHER: Product B|OTHER: Product C|OTHER: Product D|OTHER: Product E|OTHER: Product F|OTHER: Product G
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Splenectomy as a Treatment for Patient With Relapsed Haemophagocytic Lymphohistiocytosis of Unknown Etiology
Status: UNKNOWN
Conditions: Hemophagocytic Lymphohistiocytosis
Interventions: PROCEDURE: splenectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I/II Open Label Study of Belumosudil Mesylate Alone, and in Combination With Dexamethasone, in Patients With Relapsed/Refractory Multiple Myeloma
Status: RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: Belumosudil mesylate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Meal Fatty Acids on Postprandial Vascular Reactivity
Status: COMPLETED
Conditions: Cardiovascular Disease
Interventions: DIETARY_SUPPLEMENT: Saturated fat|DIETARY_SUPPLEMENT: Monounsaturated fat|DIETARY_SUPPLEMENT: n-6 polyunsaturated fat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of SI-B003, BL-B01D1+SI-B003 and BL-B01D1+PD-1 Monoclonal Antibody in Patients With Locally Advanced or Metastatic Esophageal Cancer, Gastric Cancer, Colorectal Cancer and Other Gastrointestinal Tumors
Status: RECRUITING
Conditions: Esophageal Cancer|Gastric Cancer|Colorectal Cancer
Interventions: DRUG: SI-B003|DRUG: BL-B01D1|DRUG: PD-1 Monoclonal Antibody
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A QT/QTc and Multi-Dose Pharmacokinetic Study of Abiraterone Acetate Plus Prednisone in Patients With Metastatic Castration-Resistant Prostate Cancer
Status: COMPLETED
Conditions: Prostate Neoplasms
Interventions: DRUG: Abiraterone acetate|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial of Cabazitaxel Chemotherapy in Relapsed Locally Advanced &/or Metastatic Carcinoma of the Penis
Status: COMPLETED
Conditions: Penile Neoplasm
Interventions: DRUG: Cabazitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigation of Patient Benefits With a New Supporting Ostomy Product in Patients With a Newly Stoma Formation
Status: COMPLETED
Conditions: Stoma Ileostomy|Stoma Colostomy
Interventions: DEVICE: Heylo
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Locally Advanced Pancreatic Cancer Treated With ABLAtivE Stereotactic MRI-guided Adaptive Radiation Therapy
Status: NOT_YET_RECRUITING
Conditions: Pancreatic Cancer
Interventions: RADIATION: MRIdian
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial to Evaluate the Optimal Dose of MV-LASV (V182-001)
Status: COMPLETED
Conditions: Lassa Virus Infection
Interventions: BIOLOGICAL: MV-LASV|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Probiotics in Newly Recognized Type 1 Diabetes
Status: UNKNOWN
Conditions: Diabetes Mellitus, Type 1
Interventions: DRUG: Lactobacillus rhamnosus GG and Bifidobacterium lactis BB12|OTHER: Placebo, (Placebo group)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Reduction of Intrapartum Fever With Intravenous Acetaminophen
Status: UNKNOWN
Conditions: Fever|Oxidative Stress
Interventions: DRUG: Intravenous Acetaminophen|DRUG: Oral Acetaminophen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Testosterone and Alendronate in Hypogonadal Men
Status: TERMINATED
Conditions: Hypogonadism|Osteopenia|Osteoporosis
Interventions: DRUG: Testosterone|DRUG: Alendronate|DRUG: Placebo Alendronate|DRUG: Placebo Testosterone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Revolutionizing Hepatobiliary Surgical Planning: Deep Learning-Enhanced 3D Printing Versus Traditional Digital Simulations
Status: COMPLETED
Conditions: Hepatobiliary Surgery|Liver Diseases
Interventions: DEVICE: 3D-Printed Liver Model|PROCEDURE: Digital Simulation-Based Surgical Planning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Effect of a Cognitive Task on Static Balance in Depressive Elderly Subjects According to the Double Task Principle
Status: COMPLETED
Conditions: Depression
Interventions: BEHAVIORAL: standing with both feet|BEHAVIORAL: descent of the platform|BEHAVIORAL: standing on the platform, feet together and always with simultaneous performance of a task of mental count
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: EFFECT OF A 16-SESSION QIGONG PROGRAM ON PHYSICAL AND MENTAL HEALTH IN PATIENTS WITH LYMPHOMA: A RANDOMIZED CONTROLLED TRIAL
Status: COMPLETED
Conditions: Lymphoma
Interventions: OTHER: Qigong program|OTHER: Information on healthy lifestyles, physical exercise and dietary recommendations.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pre-emptive Topical Lidocaine 5% Plaster for Prevention of Post-craniotomy Pain
Status: UNKNOWN
Conditions: Postoperative Pain|Lidocaine
Interventions: DRUG: Lidocaine 5% patch|DRUG: Placebo patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cranberry Supplementation, Viral Defense, Antibody Response to the Flu Shot
Status: COMPLETED
Conditions: Nutrition Immunology
Interventions: DIETARY_SUPPLEMENT: Cranberry|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Validation of a New Hand Held Light Emitting Diode Device for the Determination of Minimal Erythema Dose (MED)
Status: WITHDRAWN
Conditions: Phototherapy
Interventions: OTHER: LED phototherapy|OTHER: narrowband UVB phototherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Enhancement of Postocclusive Reactive Hyperaemia by Dipyridamole
Status: COMPLETED
Conditions: Hyperemia|Hypoxia
Interventions: DRUG: dipyridamole|DRUG: caffeine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Microwave vs. Radiofrequency Ablation for Benign Thyroid Nodules: A Multicenter Randomized Controlled Trial Study
Status: UNKNOWN
Conditions: Benign Thyroid Nodules|Ablation
Interventions: DEVICE: Ultrasound-guided Percutaneous Microwave Ablation|DEVICE: Ultrasound-guided Percutaneous Radiofrequency Ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial With or Without Infusion of SARS-CoV-2 Antibody Containing Plasma in High-Risk Patients With COVID-19
Status: UNKNOWN
Conditions: SARS-CoV-2 Infection
Interventions: OTHER: Convalescent/Vaccine-boosted Plasma (CP/PVP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of a 30-day Automated Text Messaging Intervention on Hospital Based Acute Care Encounters Following Ileostomy
Status: TERMINATED
Conditions: Ileostomy; Complications|Ileostomy - Stoma|Ileostomy Malfunction|Ileostomy Underactive|Complication of Surgical Procedure
Interventions: BEHAVIORAL: EpxOstomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Electrosurgical Unipolar Vessel Sealing in Vaginal Hysterectomy
Status: TERMINATED
Conditions: Vaginal Hysterectomy
Interventions: PROCEDURE: Unipolar Electrocautery sealing of vessels|PROCEDURE: Purohit technique for vaginal hysterectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Rules for Insulin Dosing in Patients Using Multiple Daily Injections
Status: UNKNOWN
Conditions: Diabetes Mellitus Type 1
Interventions: DRUG: Lispro Insulin and glargine insulin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility Clinical Trial of the Cardio Flow Orbital Atherectomy System to Treat Peripheral Artery Disease (PAD)
Status: COMPLETED
Conditions: Peripheral Arterial Disease
Interventions: DEVICE: Cardio Flow FreedomFlow™ Orbital Atherectomy System treatment|DEVICE: Balloon Angioplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimised Recovery With Accelerated Nutrition and GI Enhancement
Status: COMPLETED
Conditions: Colorectal Liver Metastases
Interventions: DRUG: Post operative laxation (Magnesium Oxide)|DIETARY_SUPPLEMENT: Preoperative metabolic conditioning postoperative nutritional supplementation|OTHER: Standard ERAS group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Post-therapeutic Imaging Evaluation of Patients With Horton's Disease (Giant Cell Arteritis) (EvHortim)
Status: RECRUITING
Conditions: Giant Cell Arteritis
Interventions: DIAGNOSTIC_TEST: Injected cerebral MRI angiography and ultrasound of the superior aortic trunks, temporal and axillary arteries
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparing Quetiapine XR Monotherapy and Augmentation With Lithium Augmentation in TRD Patients
Status: COMPLETED
Conditions: Major Depressive Disorder|Treatment Resistant Depression
Interventions: DRUG: Quetiapine XR|DRUG: Lithium carbonate|DRUG: SSRI/Venlafaxine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Activity and Safety of Oral Administration of SSR150106XB for the Reduction of Inflammation in Patients With Active Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: SSR150106|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Open-label Phase IV Clinical Trial to Evaluate the Safety and Tolerability of Zoledronic Acid in Patients With Prostate Cancer and Bone Metastases
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: Zoledronic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Programmed Environmental Illumination (PEI) of Hospital Rooms to Prevent/Reduce Cancer-Related Fatigue
Status: COMPLETED
Conditions: Cancer-related Problem/Condition|Depression|Circadian Rhythm Disorders
Interventions: DEVICE: PEI Experimental Light|DEVICE: Comparison Light
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Local Infiltration Analgesia With Ropivacaine in Posterior Vaginal Wall Prolapse:a Randomized, Double-Blind Study
Status: COMPLETED
Conditions: Vaginal Prolapse
Interventions: DRUG: Ropivacaine|DRUG: Isotonic NaCl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Nivolumab and Oral Cyclophosphamide for R/R AML and HIgh Risk MDS
Status: COMPLETED
Conditions: Acute Myeloid Leukemia|Higher Risk Myelodysplastic Syndrome
Interventions: DRUG: Nivolumab|DRUG: Low dose Cyclophosphamide (CTX) Daily|DRUG: Low dose Cyclophosphamide (CTX) Every 7 Days
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Euglycemic Clamp Dose-response Study Comparing a New Insulin Glargine Formulation With Lantus®
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus
Interventions: DRUG: Insulin glargine (HOE901)|DRUG: Insulin glargine (HOE901)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Role of [18F]-FDG Brain PET in Newly Diagnosed Primary Cerebral Lymphoma, in Immunocompetent Patient Older Than 60 Years
Status: UNKNOWN
Conditions: Primary Central Nervous System Lymphoma
Interventions: RADIATION: [18F]-FDG PET/MR
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Investigation of the Efficacy of Metformin Therapy on Pulmonary Sarcoidosis
Status: NOT_YET_RECRUITING
Conditions: Sarcoidosis, Pulmonary
Interventions: DRUG: Metformin|DRUG: Cellulose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Blood Glucose Monitoring Devices With New Insight Features
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: DEVICE: OneTouch Verio®|DEVICE: OneTouch Verio® Flex|DEVICE: Subject's Own Blood Glucose Meter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Evaluation of the Contribution of Low-pressure Intra-abdominal Insufflation for Laparoscopic Colic Resection
Status: COMPLETED
Conditions: Colonic Disease
Interventions: PROCEDURE: Conventional pressure laparoscopy|PROCEDURE: Low pressure laparoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT