pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: The CBF Study Evaluating the Effect of Betahistine on the Cerebral Blood Flow
Status: COMPLETED
Conditions: Gait or Balance Disorder Problems
Interventions: DRUG: betahistine dihydrochloride|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treating Pediatric NAFLD With Nutrition
Status: RECRUITING
Conditions: Non-Alcoholic Fatty Liver Disease|Liver Diseases|Liver Fat|Hepatic Steatosis|Nutritional and Metabolic Disease
Interventions: OTHER: Whole Dairy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Methylcobalamin and Cyanocobalamin Consumption on Vitamin B12 Nutritional Status
Status: RECRUITING
Conditions: Vitamin B12 Nutritional Deficiency
Interventions: DIETARY_SUPPLEMENT: Methylcobalamin|DIETARY_SUPPLEMENT: Cyanocobalamin group|DIETARY_SUPPLEMENT: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Combination of Ipi/Nivo Plus Sacituzumab Govitecan in Metastatic Cisplatin Ineligible Urothelial Carcinoma Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Urothelial Carcinoma
Interventions: DRUG: Ipilimumab|DRUG: Nivolumab|DRUG: Sacituzumab govitecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Ramosetron Plus DX, Dexamethasone, Compared to Granisetron Plus DX for the Prevention of Vomiting and Nausea
Status: COMPLETED
Conditions: Vomiting|Nausea
Interventions: DRUG: Ramosetron|DRUG: Granisetron
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Effect of an Individualized Physical Activity Intervention for Gastric Cancer Patient Undergoing Minimally Invasive Gastrectomy: a Phase III, Prospective Randomized Controlled Trial
Status: COMPLETED
Conditions: Gastric Cancer
Interventions: BEHAVIORAL: physical activity intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: the Sequential Therapy of CD19-targeted and CD20-targeted CAR-T Cell Therapy for Diffuse Large B Cell Lymphoma(DLBCL)
Status: UNKNOWN
Conditions: Lymphoma, Large B-Cell, Diffuse
Interventions: BIOLOGICAL: Anti-CD19 CAR-T cells and Anti-CD20 CAR-T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Impact of Indocyanine Green-enhanced Fluorescence Imaging on Bowel Transection in Left-sided Colorectal Resection
Status: UNKNOWN
Conditions: Anastomotic Leak
Interventions: DRUG: indocyanine green|DEVICE: Fluorescence imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Application of KANG FU PEN in Radical Concurrent Radiotherapy and Chemotherapy for Cervical Cancer to Prevent and Treat Radiation-induced Rectal Injury
Status: RECRUITING
Conditions: Cervical Cancer|Radiotherapy Side Effect|Radiotherapy; Complications
Interventions: DRUG: KANG FU PEN
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Observational Study Investigating the Effectiveness of Fentanyl Matrix in Relieving Pain and Improving Function in Patients With Osteoarthritis of the Knee or Hip
Status: COMPLETED
Conditions: Pain|Osteoarthritis, Hip|Osteoarthritis, Knee
Interventions: DRUG: fentanyl matrix|DRUG: fentanyl matrix
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Validation Study of the Lab Clasp Device: A Point of Care Sepsis Risk Monitor
Status: ACTIVE_NOT_RECRUITING
Conditions: Sepsis|Sepsis Bacterial|Lactate Blood Increase|Infectious Disease
Interventions: DEVICE: Lab Clasp
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Mild Compression Sock for Control of Lower Extremity Edema in Individuals With Diabetes
Status: COMPLETED
Conditions: Edema
Interventions: DEVICE: mild compression diabetic sock|DEVICE: Standard diabetic sock
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Elbow Arthroscopy Data Analysis
Status: ACTIVE_NOT_RECRUITING
Conditions: Osteoarthritis Elbow Left|Osteoarthritis Elbow Right|Lateral Epicondylitis, Left Elbow|Lateral Epicondylitis, Right Elbow|Plica Syndromes|Osteochondritis Dissecans
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Imatinib Mesylate (Gleevec) and Docetaxel in Patients With Head and Neck Squamous Cell Cancer
Status: COMPLETED
Conditions: Head and Neck Cancer|Squamous Cell Cancer
Interventions: DRUG: Imatinib Mesylate|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endocrine Therapy + OSI-906 With or Without Erlotinib for Hormone-Sensitive Metastatic Breast Cancer
Status: TERMINATED
Conditions: Hormone-sensitive Metastatic Breast Cancer
Interventions: DRUG: OSI-906|DRUG: Erlotinib|DRUG: Letrozole|DRUG: Goserelin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating Impact and Implementation of Choose to Move (Phase 4)
Status: ACTIVE_NOT_RECRUITING
Conditions: Aging|Mobility Limitation|Sedentary Behaviour|Loneliness|Social Isolation|Social Connectedness
Interventions: BEHAVIORAL: Choose to Move
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Interactive Mobile Doctor (iMD) to Promote Tobacco Cessation Among Cancer Patients
Status: RECRUITING
Conditions: Tobacco Dependence|Tobacco Use Cessation|Cancer
Interventions: OTHER: Interactive Mobile Doctor (iMD)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study of Oral Dasatinib in Subjects With Myelodysplastic Syndrome (MDS) and Excess Marrow Blasts
Status: COMPLETED
Conditions: Myelodysplastic Syndromes
Interventions: DRUG: Dasatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Trifunctional Antibody Catumaxomab to Treat Recurrent Symptomatic Malignant Ascites
Status: COMPLETED
Conditions: Malignant Ascites
Interventions: DRUG: catumaxomab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Dexmedetomidine and Midazolam for Intra-op Sedation in TIVA in Children Undergoing Inguinal Hernia Repair
Status: UNKNOWN
Conditions: Inguinal Hernia
Interventions: DRUG: Dexmedetomidine|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effectiveness of autoHYpnosis in the Prevention of Anxiety During Radiotherapy of Head and Neck Tumors (HYMACO)
Status: RECRUITING
Conditions: Head and Neck Tumors
Interventions: OTHER: Standard care|OTHER: Autohypnosis|OTHER: Musicotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Neural Responses and Dysphoria: Modulation by a Pharmacological Probe
Status: COMPLETED
Conditions: Dysphoria
Interventions: DRUG: Escitalopram|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Phase II Study of SPI-1620 in Combination With Docetaxel as a Second-Line to Treat Biliary Cancer
Status: TERMINATED
Conditions: Biliary Cancer
Interventions: DRUG: SPI-1620|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stem Cell (Modified Bone Marrow) Transplantation in HIV-Infected Patients With Blood Cancer
Status: COMPLETED
Conditions: Hematologic Neoplasm|HIV Infection
Interventions: DRUG: GCSF Mobilized Allogeneic PBSC Cultured w/Cytokines; Transduced w/RV
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: A Trial to Investigate the Single Dose Pharmacokinetics of Insulin Degludec/Liraglutide Compared With Insulin Degludec and Liraglutide in Healthy Chinese Subjects
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: insulin degludec/liraglutide|DRUG: insulin degludec|DRUG: liraglutide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Preoperative Intervention With Folic Acid and Vitamin B12 on Postoperative Neurobehavioral Changes in Children
Status: RECRUITING
Conditions: Delirium
Interventions: DIETARY_SUPPLEMENT: Folic acid and vitamin B12|DIETARY_SUPPLEMENT: brown sugar aqueous
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study to Assess Safety and Efficacy of PRI-002 in Patients With MCI to Mild Dementia Due to Alzheimer's Disease (AD)
Status: RECRUITING
Conditions: Mild Cognitive Impairment Due to Alzheimer's Disease|Alzheimer's Disease, Early Onset
Interventions: DRUG: PRI-002|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Imprime PGG, Alemtuzumab, and Rituximab in Treating Patients With High Risk Chronic Lymphocytic Leukemia
Status: COMPLETED
Conditions: B-cell Chronic Lymphocytic Leukemia|Refractory Chronic Lymphocytic Leukemia|Stage 0 Chronic Lymphocytic Leukemia|Stage I Chronic Lymphocytic Leukemia|Stage II Chronic Lymphocytic Leukemia
Interventions: BIOLOGICAL: alemtuzumab|BIOLOGICAL: rituximab|DRUG: PGG beta-glucan|OTHER: flow cytometry|OTHER: laboratory biomarker analysis|GENETIC: DNA analysis|GENETIC: fluorescence in situ hybridization|GENETIC: polymerase chain reaction|GENETIC: polymorphism analysis|GENETIC: mutation analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Dronabinol (Oral THC) on Cannabis Use
Status: COMPLETED
Conditions: Marijuana Smoking
Interventions: DRUG: Dronabinol 120mg/day|DRUG: Placebo|DRUG: Dronabinol 240mg/day
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Analysis of Data Collected in the European Group for Blood and Marrow Transplantation (EBMT) Registry for Off-Label Transplant Use of Plerixafor
Status: COMPLETED
Conditions: Acute Leukemia|Chronic Leukemia|Myelodysplastic Syndrome|Myeloproliferative Neoplasm|Solid Tumors|Lymphoma|Plasma Cell Disorders
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison Between TICL and ICL+AK for High Myopic Astigmatism
Status: COMPLETED
Conditions: Astigmatism|High Myopia
Interventions: DEVICE: Toric Implantable Collamer Lens|DEVICE: ICL + Astigmatic keratotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety & Immunogenicity of RVM-V001/RVM-V002 or RVMV001+RVMV002 (Co Administered as Separate Injections) in Healthy Individuals
Status: TERMINATED
Conditions: Infectious Disease|COVID-19
Interventions: BIOLOGICAL: RVM-V001 30 µg|BIOLOGICAL: RVM-V002 30 µg|BIOLOGICAL: RVM-V001 (15 µg) + RVM-V002 (15 µg) co-administration|BIOLOGICAL: RVM-V001 30 µg|BIOLOGICAL: RVM-V002 30 µg|BIOLOGICAL: RVM-V001 (15 µg) + RVM-V002 (15 µg) co-administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effect of Pre-Frontal tDCS on Sleep Propensity During an Afternoon Nap: RCT
Status: COMPLETED
Conditions: Sleep
Interventions: DEVICE: transcranial Direct Current Stimulation (tDCS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Time to Intubation (TTI) of Obese Patients. A Comparison Macintosh Laryngoscope and Stortz Video Laryngoscope
Status: COMPLETED
Conditions: Obese
Interventions: DEVICE: Conventional Macintosh laryngoscope|DEVICE: Stortz videolaryngoscope
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of Grazoprevir (MK-5172) in Hepatitis C-Infected Male Participants (MK-5172-004)
Status: COMPLETED
Conditions: Hepatitis C
Interventions: DRUG: Grazoprevir|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Inactivated and Live, Attenuated Influenza Vaccine in Children 5-9 Years of Age-Year 3 Amendment
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: FluMist|BIOLOGICAL: Fluzone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to Assess the Efficacy of RO5459072 in Participants With Primary Sjogren's Syndrome
Status: COMPLETED
Conditions: Sjogren's Syndrome
Interventions: DRUG: Placebo|DRUG: RO5459072
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: D-chiro Inositol in Prevention of Gestational Diabetes Mellitus in China
Status: COMPLETED
Conditions: Gestational Diabetes Mellitus in Pregnancy
Interventions: DIETARY_SUPPLEMENT: D-chiro inositol|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Comparison of ANCA and Anti-GBM Auto-antibodies Removal Kinetics Between Plasma Exchanges and Immunoadsorption in Patients With ANCA-associated Vasculitis or Anti-GBM Disease
Status: UNKNOWN
Conditions: Kidney Failure, Acute
Interventions: PROCEDURE: Apheresis technics
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Dose-Escalation Study Designed to Evaluate the Tolerability, Safety, Pharmacokinetics (PK), and Efficacy of Chronic Topical Ocular Application of INO-8875 in Adults With Ocular Hypertension or Primary Open-Angle Glaucoma
Status: COMPLETED
Conditions: Glaucoma|Ocular Hypertension
Interventions: DRUG: INO-8875|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Internet-delivered Cognitive Behaviour Therapy (ICBT) for Post-secondary Students
Status: COMPLETED
Conditions: Anxiety|Depression
Interventions: BEHAVIORAL: Internet-delivered cognitive behaviour therapy|BEHAVIORAL: Motivational Interviewing|BEHAVIORAL: Booster Session
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Long-acting Levodopa on Obstructive Sleep Apnea in Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson's Disease|Obstructive Sleep Apnea
Interventions: DRUG: Sinemet CR|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Distribution of FMT After Delivery by · Lower GI Endoscopy vs Enema With and Without Positioning of the Patient
Status: COMPLETED
Conditions: Fecal Microbiota Transplantation
Interventions: OTHER: Delivery of contrast fluid by lower GI endoscopy|OTHER: Delivery of contrast fluid by enema with and without positioning
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Studying Physiological and Anatomical Cerebral Effects of Carbon Dioxide and Tilt
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: 0.5% CO2|OTHER: ambient air
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effectiveness of Lymphatic Bypass Supermicrosurgery
Status: RECRUITING
Conditions: Breast Cancer Related Lymphedema|Lymphedema Arm
Interventions: PROCEDURE: Lymphatic Bypass Supermicrosurgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Effect Psychological Triaging Intervention on Students' Psychological Distress and Resilience Capacity
Status: COMPLETED
Conditions: Psychological Distress|Resilience
Interventions: BEHAVIORAL: Psychological Triaging Intervention|BEHAVIORAL: Routine psychological support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Nonmyeloablative Peripheral Blood Stem Cell Transplant With High-dose Posttransplantation Cyclophosphamide in Hematopoietic Malignancies Including Those That Are Challenging to Engraft
Status: TERMINATED
Conditions: Hematopoietic Malignancies
Interventions: DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study on Fermentable Carbohydrates in Healthy Infants
Status: COMPLETED
Conditions: Infant|Growth|Nutrition|Healthy
Interventions: DIETARY_SUPPLEMENT: Fermentable carbohydrates.|OTHER: Standard infant formula.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose:
Clinical trial: Quick Epidural Top-up With Alkalinized Lidocaine for Emergent Caesarean Delivery
Status: COMPLETED
Conditions: Obstetric Labor Complications
Interventions: DRUG: Lidocaine epinephrine buffered with sodium bicarbonate|DRUG: Lidocaine epinephrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Role of Emotional Freedom Techniques in Reducing Postoperative Nausea and Vomiting After Laparoscopic Cholecystectomy
Status: COMPLETED
Conditions: Postoperative Nausea and Vomiting
Interventions: BEHAVIORAL: EFTs (emotional freedom techniques)|DRUG: Tab. Midazolam 7.5 mg|DRUG: Inj. Midazolam 0.7mg/kg|DRUG: Inj. Propofol 2.5mg/kg|DRUG: Inj. Atracurium 0.5 mg/kg|DRUG: Sevoflurane 2.5 vol %|DRUG: Inj. Cefuroxime 1.5 g IV|DRUG: Drug: Inj. Ketorolac 30 mg IV|DRUG: Inj. Zantac 50mg IV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Index of Microcirculatory Resistance After Drug-Eluting Stent Implantation With High Dose Atorvastatin Loading
Status: UNKNOWN
Conditions: Acute Coronary Syndrome
Interventions: DRUG: Pre-procedural High dose atorvastatin loading|DRUG: No pre-procedural high-dose atorvastatin loading
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cortisone or Drug Eluting Stents (DES) as Compared to Bare Metal Stents (BMS) to EliminAte Restenosis
Status: COMPLETED
Conditions: Coronary Artery Disease|Ischemic Heart Disease|Atherosclerosis
Interventions: DRUG: Prednisone|DEVICE: Drug eluting coronary stent|DEVICE: Bare metal coronary stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Cerebrospinal Fluid Samples in Diagnosing Carcinomatous Meningitis in Patients With Cancer or Meningeal Syndrome
Status: UNKNOWN
Conditions: Brain and Central Nervous System Tumors|Breast Cancer|Metastatic Cancer
Interventions: OTHER: diagnostic laboratory biomarker analysis|OTHER: immunoenzyme technique|PROCEDURE: magnetic resonance imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The ARIES HeartMate 3 Pump IDE Study
Status: COMPLETED
Conditions: Heart Failure
Interventions: DEVICE: LVAD Implant|DRUG: Aspirin 100mg|DRUG: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Evaluate the Efficacy and Safety of ABBV-8E12 in Participants With Early Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: ABBV-8E12|DRUG: placebo for ABBV-8E12
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ivermectin and Nitazoxanide Combination Therapy for COVID-19
Status: UNKNOWN
Conditions: COVID-19
Interventions: COMBINATION_PRODUCT: Ivermectin plus Nitazoxanide|OTHER: Standard Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Pharmacokinetics of Intra-articular (IA) Single Ascending Dose of 4P-004 in Patient With Kellgren and Lawrence Grade 2 to 4 Osteoarthritic (OA) Knee
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: DRUG: 4P-004|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Two-Part, Open-Label, Multi-Center, Phase 1/2 Study of BIW-8962 as Monotherapy in Subjects With Lung Cancer
Status: TERMINATED
Conditions: Phase 1 Portion : Non Small Cell Lung Cancer(NSCLC), Small Cell Lung Cancer(SCLC), Mesothelioma|Phase 2 Portion : Small Cell Lung Cancer(SCLC)
Interventions: DRUG: BIW-8962
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy Plus Subsequent Loco-regional Radiotherapy Combined With Toripalimab in the De Novo Metastatic Nasopharyngeal Carcinoma
Status: UNKNOWN
Conditions: Nasopharyngeal Carcinoma
Interventions: DRUG: Chemotherapy plus radiotherapy and Toripalimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PCA Ketamine-Morphine VS PCA Morphine as Post-Operative Analgesia in Colorectal Surgery.
Status: COMPLETED
Conditions: Ketamine|Morphine
Interventions: DRUG: Ketamine-Morphine|DRUG: Morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Virtual Reality-Based Disaster Education Given to Nursing Students on Disaster Preparedness
Status: COMPLETED
Conditions: Disaster; Personality|Disorder, Mood
Interventions: BEHAVIORAL: virtual reality
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Investigate the Safety, Pharmacokinetics, and Clinical Activity of AP203 in Patients With Locally Advanced or Metastatic Solid Tumors, and Expansion to Selected Malignancies
Status: NOT_YET_RECRUITING
Conditions: Locally Advanced or Metastatic Solid Tumors|Non Small Cell Lung Cancer (NSCLC)|Head and Neck Squamous Cell Carcinoma (HNSCC)|Esophageal Squamous Cell Carcinoma (ESCC)
Interventions: DRUG: AP203|DRUG: AP203
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Evaluate the Efficacy and Safety of DW1903 in Acute and Chronic Gastritis Patient
Status: COMPLETED
Conditions: Gastritis Acute|Gastritis Chronic
Interventions: DRUG: DW1903|DRUG: DW1903-R1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Reliability of ULRT in Overhead Athletes and Its Relationship With Selected UEPT
Status: COMPLETED
Conditions: Upper Limb Asymmetry
Interventions: DIAGNOSTIC_TEST: Upper Limb Rotation Test|DIAGNOSTIC_TEST: Closed Kinetic Chain Upper Extremity Stability Test|DIAGNOSTIC_TEST: Upper Quarter Y Balance Test
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effects of Low-dose Atropine and Orthokeratology in Pediatric Myopia Control
Status: UNKNOWN
Conditions: Myopia
Interventions: DRUG: low-dose atropine eye drops|DEVICE: orthokeratology
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immunity Modification of Full Term Infants According to the Type of Feeding and Mode of Delivery
Status: UNKNOWN
Conditions: Innate Immunity
Interventions: DIETARY_SUPPLEMENT: Feeding infants with formula milk with fermented matrix at dosage of 4.6 g per 100g of powder|DIETARY_SUPPLEMENT: Feeding infants with formula milk with fermented matrix at dosage of 6.9 g per 100g of powder|OTHER: Feeding infants with standard formula milk|OTHER: Breastfeeding infants
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy Study of 4975 in Patients Undergoing Total Knee Replacement
Status: COMPLETED
Conditions: Total Knee Arthroplasty (Replacement)
Interventions: DRUG: 4975, 15 and 5 mg|DRUG: Placebo Comparator|DRUG: 4975 - 5 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Unmasking Right Ventricular and Pulmonary Derangements With Exercise and Oxygen in Early Stage Cardiopulmonary Diseases
Status: COMPLETED
Conditions: Cardiopulmonary Disease
Interventions: OTHER: Echocardiography|OTHER: Pulmonary Gas Exchange
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: IMPAACT P1058A: Pharmacokinetic Effects of New Antiretroviral Drugs on Children, Adolescents and Young Adults
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Raltegravir (RAL)|DRUG: Atazanavir (ATV)|DRUG: Ritonavir (RTV)|DRUG: Tenofovir (TDF)|DRUG: Etravirine (ETV)|DRUG: Darunavir (DRV)|DRUG: Maraviroc (MVC)|DRUG: Lopinavir/ritonavir (LPV/r)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Parenteral Nutrition Supplement on Esophagectomy Patients
Status: COMPLETED
Conditions: Esophagus Cancer
Interventions: OTHER: Parenteral supplement with enteral nutrition for patients after esophagectomy|OTHER: Enteral Nutrition alone for patients after esophagectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study on the Occurrence of Possible Relapses and on the Quality of Life in Patients Who Underwent TURBK.
Status: RECRUITING
Conditions: Non Muscle Invasive Bladder Cancer|Non-Muscle Invasive Bladder Neoplasms|Non-Muscle Invasive Bladder Urothelial Carcinoma|Bladder Cancer|Bladder Disease|Bladder Neoplasm|Bladder Urothelial Carcinoma|Bladder Cancer Stage I, With Cancer in Situ|Bladder Cancer Recurrent|Bladder Urothelial Carcinoma in Situ|Bladder Urothelial Dysplasia
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Single-dose Study in Two Panels of Healthy Adult Participants to Assess Immediate-Release and Dispersible Formulations of Pretomanid
Status: COMPLETED
Conditions: Multi-drug Resistant Tuberculosis
Interventions: DRUG: Pretomanid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of LP-300 With Carboplatin and Pemetrexed in Never Smokers With Advanced Lung Adenocarcinoma
Status: RECRUITING
Conditions: Adenocarcinoma of Lung|Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: LP-300|DRUG: Pemetrexed|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Intravenous Paracetamol and Ibuprofen on Postoperative Pain and Morphine Consumption in Hysterectomy
Status: COMPLETED
Conditions: Postoperative Pain Management
Interventions: DRUG: Morphine Sulfate|DRUG: Intravenous paracetamol|DRUG: Intravenous ibuprofen|DRUG: Morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Combination Study of PF-04449913 (Glasdegib) and Azacitidine In Untreated MDS, AML and CMML Patients
Status: COMPLETED
Conditions: Myelodysplastic Syndrome|Acute Myeloid Leukemia|Chronic Myelomonocytic Leukemia
Interventions: DRUG: PF-04449913 (Glasdegib)|DRUG: Azacitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multispectral Bimodal Fluorescence Guided Surgery of High-grade Glioma With Cetuximab-800CW and 5-ALA (5-aminolevulinic Acid)
Status: RECRUITING
Conditions: Glioblastoma|High-grade Glioma
Interventions: DRUG: Cetuximab-IRDye800
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Educational-Medical-Behavioral Treatment of Fecal Incontinence
Status: TERMINATED
Conditions: Fecal Incontinence
Interventions: OTHER: Education|DIETARY_SUPPLEMENT: Fiber supplements|DRUG: Laxatives or anti-diarrheals|BEHAVIORAL: Pelvic floor muscle exercises|BEHAVIORAL: Tips on how to prevent fecal incontinence|BEHAVIORAL: Daily diary|OTHER: Protective pads or garments
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of DIDALA Monotherapy in Patients With Type 2 Diabetes Compared With Metformin.
Status: NOT_YET_RECRUITING
Conditions: Type 2 Diabetes
Interventions: DRUG: DIDALA hard capsules|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of IMC-I109V in Non-cirrhotic HBeAg-negative Chronic HBV Infection
Status: RECRUITING
Conditions: Hepatitis B, Chronic
Interventions: DRUG: IMC-I109V Single Ascending Dose|DRUG: IMC-I109V Multiple Ascending Doses|DRUG: HBV HCC Module MAD
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacist-Physician Collaborative Medication Therapy Management Services (MTMS) Demonstration Project
Status: COMPLETED
Conditions: Hypertension
Interventions: OTHER: Pharmacist-Physician Collaborative Medication Therapy Management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Comparison of the Q-NRG+ Indirect Calorimetry Device Versus the V(Max) Encore Device in Mechanically Ventilated Children
Status: RECRUITING
Conditions: Calorimetry, Indirect|Oxygen Consumption|Metabolism|Mechanical Ventilation
Interventions: DEVICE: Q-NRG+ Indirect Calorimetry Device|DEVICE: V(max) Encore Indirect Calorimetry Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effect of Dexamedetomidine for Interscalene Brachial Plexus Block on Plasma Biomarkers After Rotator Cuff Repair
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: dexmedetomidine|PROCEDURE: ISB|DRUG: Ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Clinical Trial Scheme of Tanreqing Capsules in the Treatment of COVID-19
Status: COMPLETED
Conditions: Novel Coronavirus Pneumonia
Interventions: DRUG: Tanreqing capsule|DRUG: Tanreqing capsule simulator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I/II Pilot Treatment Study Of CSF Penetration And Response To Ganciclovir And Foscarnet In CMV Neurologic Disease.
Status: WITHDRAWN
Conditions: Encephalopathy|HIV Infections|Radiculitis
Interventions: DRUG: Foscarnet sodium|DRUG: Ganciclovir
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: Salvage Surgeries for Splanchnic Artery Aneurysms After Failed Endovascular Therapies: Cases Series
Status: COMPLETED
Conditions: Failure in Endovascular Therapy|Splanchnic Aneurysm|Mass Effect|Surgery
Interventions: PROCEDURE: Aneurysmectomy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Methylphenidate for Cancer-Related Fatigue
Status: TERMINATED
Conditions: Cancer
Interventions: DRUG: methylphenidate|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Perifosine in Treating Patients With Refractory Solid Tumors or Hematologic Cancer
Status: COMPLETED
Conditions: Leukemia|Lymphoma|Myelodysplastic Syndromes|Myelodysplastic/Myeloproliferative Neoplasms|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: perifosine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Efficacy and Tolerance of Honey-impregnated Dressings in the Local Management of Pressure Ulcers
Status: TERMINATED
Conditions: Pressure Ulcer
Interventions: DEVICE: MELECTIS G|PROCEDURE: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of a Sub-maximal Exercise Program on Adolescents Who Sustained a Concussion
Status: COMPLETED
Conditions: Concussion, Mild|Concussion, Brain|Concussion, Severe|Exertion; Excess
Interventions: OTHER: Sub-maximal exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Dose-response Evaluation of the SQ Tree SLIT-tablet Using an Environmental Exposure Chamber
Status: COMPLETED
Conditions: Allergic Rhinoconjunctivitis
Interventions: DRUG: SQ tree SLIT-tablet|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neurophysiological Measures of Auditory Perception and Rehabilitation in Cochlear Implanted Patients
Status: COMPLETED
Conditions: Deafness
Interventions: OTHER: Auditory steady-state response ASSR|OTHER: Speech-ABR|OTHER: Acoustic Change Complex ACC|OTHER: P1-N1-P2 complex and Mismatch Negativity MMN
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Temporomandibular Joint Problems and Core Stabilization
Status: COMPLETED
Conditions: Temporomandibular Joint Disorders|Core Stability
Interventions: OTHER: TMJ dysfunction|OTHER: Maximum pain-free mouth opening (MMO)|OTHER: Forward head posture|OTHER: Tongue strength and endurance|OTHER: Static endurance evaluation of the trunk muscles|OTHER: Dynamic endurance evaluation of the core muscles
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Bioelectric Stimulation in Patients With Non-Dialysis Dependent Chronic Kidney Disease
Status: UNKNOWN
Conditions: Renal Insufficiency, Chronic|Electric Stimulation
Interventions: DEVICE: Bioelectric stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Safety, Tolerability, Pharmacokinetics, and Effect on Disease Progression of BIIB078 Administered to Previously Treated Adults C9ORF72-Associated Amyotrophic Lateral Sclerosis (ALS)
Status: TERMINATED
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DRUG: BIIB078
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Sustained Natural Apophyseal Glides Versus Cervical Manipulation on Pain and Disability in Wrestle
Status: COMPLETED
Conditions: Neck Pain|Disability Physical
Interventions: OTHER: SNAGs|OTHER: Manipulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Project HOME: Home-Based Treatment Options and Mechanisms for Eating Disorders
Status: RECRUITING
Conditions: Anorexia Nervosa|Eating Disorders
Interventions: BEHAVIORAL: Family-based treatment (FBT)|BEHAVIORAL: Integrative family therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Parasternal Subpectoral Plane Blocks for Cardiac Surgery Via a Midline Sternotomy
Status: UNKNOWN
Conditions: Pain, Postoperative
Interventions: PROCEDURE: Parasternal Subpectoral Plane Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of the Endotracheal Tube Used in Prone Position Ventilation Condition
Status: COMPLETED
Conditions: Mechanical Ventilation Complication
Interventions: DEVICE: prone position endotracheal tube(PPT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Controlled Exposure of Healthy Nonsmokers to Secondhand and Thirdhand Cigarette Smoke
Status: SUSPENDED
Conditions: Pollution; Exposure|Smoke Inhalation|Exposure to Pollution
Interventions: OTHER: Cigarette Smoke|OTHER: Clean Air and Clean Clothing/Sham exposure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: E-T Tube Cuff Pressure Change After Changing Position From Neutral to Hyperextension of Neck
Status: UNKNOWN
Conditions: Thyroidectomy
Interventions: DEVICE: Mallinckrodt, COVIDIEN|DEVICE: Endotracheal tube, Unomedica
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Alisertib and TAK-228 in Participants With Human Papilloma Virus (HPV) Associated Malignancies
Status: WITHDRAWN
Conditions: Malignant Neoplasms of Digestive Organs|Malignant Neoplasms of Female Genital Organs|Malignant Neoplasms of Lip Oral Cavity and Pharynx|Malignant Neoplasms of Male Genital Organs
Interventions: DRUG: Alisertib|DRUG: TAK-228
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Physiological Impact of Surgical Mask and N95 Mask on Obese Operating Room
Status: COMPLETED
Conditions: Obesity
Interventions: DEVICE: N95 mask and surgical mask
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Oxidative Stress In Semen And Male Infertility
Status: UNKNOWN
Conditions: Antioxidants|Infertility, Male|Semen Quality
Interventions: DRUG: Fairhaven Pro for men|DIAGNOSTIC_TEST: Semen analysis|DIAGNOSTIC_TEST: Sperm DNA fragmentation|DIAGNOSTIC_TEST: Static Oxidation reduction potential in semen
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective, Non-interventional, Multi-center Safety Study of Mirena for Heavy Menstrual Bleeding and Dysmenorrhea
Status: COMPLETED
Conditions: Menorrhagia, Dysmenorrhea
Interventions: DRUG: Levonorgestrel IUS (Mirena, BAY86-5028)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Blood Loss Reduction After Total Knee Arthroplasty. Comparison Topical Tranexamic Acid vs Platelet Rich Plasma
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DRUG: Group 1 Tranexamic Acid|BIOLOGICAL: Group 2 Platelet rich plasma
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Therapeutic Tapping in Primary Dysmenorrhea
Status: COMPLETED
Conditions: Primary Dysmenorrhea
Interventions: OTHER: KinesioTape|OTHER: Sham Tape|OTHER: General Physio session
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of BMS-908662 in Combination With Ipilimumab in Subjects With Advanced Melanoma
Status: COMPLETED
Conditions: Melanoma
Interventions: DRUG: BMS-908662|DRUG: BMS-908662|DRUG: Ipilimumab|DRUG: Ipilimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Culturally-Adapted Diet for Puerto Rican Adults
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Obesity|Hypertension|Dyslipidemias|High Triglycerides|High Blood Glucose|Abdominal Obesity
Interventions: BEHAVIORAL: Culturally tailored food and diet advice|BEHAVIORAL: Standard healthy eating advice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Assessment of the Reliability and Validity of the Leg Lateral Reach Test in Adolescent Tennis Players
Status: COMPLETED
Conditions: Trunk Injury|Mobility Limitation|Spine Injury|Athletic Injuries
Interventions: DIAGNOSTIC_TEST: Leg Lateral Reach Test
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Investigation of Antipsoriatic Effects of UVB-induced Synthesis of 1alpha, 25-Dihydroxyvitamin D3 (1alpha, 25(OH)2D3, Calcitriol)in Keratinocytes of Psoriatic Skin, Using Cytochrom-P(CYP)Inhibitor Ketokonazol
Status: UNKNOWN
Conditions: Psoriasis Vulgaris
Interventions: DRUG: Ketokonazol 2% cream|RADIATION: UVB-radiation 311nm
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: VINCI-AD: An Investigation of Transcutaneous Vagus Nerve Stimulation in Mild Cognitive Impairment.
Status: COMPLETED
Conditions: Mild Cognitive Impairment|Neurocardiogenic Syncope|Memory Impairment|Inflammatory Response|Alzheimer Disease
Interventions: DEVICE: Active t-VNS|DEVICE: Sham t-VNS|OTHER: Baseline assessments
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: An Open-Label, Randomized Pilot Study Comparing the Safety of a Single Dose of TNX-1300 to Usual Care (UC) Alone for the Treatment of Signs and Symptoms of Acute Cocaine Intoxication in Male Emergency Department (ED) Subjects
Status: WITHDRAWN
Conditions: Cocaine Intoxication
Interventions: DRUG: TNX-1300|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tofacitinib Registry of Patients With Ulcerative Colitis in Germany
Status: TERMINATED
Conditions: Colitis, Ulcerative|Biologics|Tofacitiniib|Chronic Inflammatory Small Bowel Disease|Bowel Diseases, Inflammatory|Bowel Disease|CED
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: High Spinal Anesthesia and the Incidence of Delirium After Cardiac Surgery
Status: ACTIVE_NOT_RECRUITING
Conditions: Post-Operative Confusion
Interventions: DRUG: Intrathecal bupivacaine and morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: The Effect of a 2-week Preoperative Vegan Diet Versus Omnivorous Diet on the Protein Turnover in the Osteoarthritic Knee
Status: NOT_YET_RECRUITING
Conditions: Osteo Arthritis Knee|Protein Synthesis
Interventions: DIETARY_SUPPLEMENT: Vegan diet|DIETARY_SUPPLEMENT: Omnivorous diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Tenofovir Disoproxil Fumarate (TDF) in Chinese Chronic Hepatitis B (CHB) Subjects With Advanced Fibrosis & Compensated Cirrhosis
Status: COMPLETED
Conditions: Hepatitis B, Chronic
Interventions: DRUG: Tenofovir disoproxil fumarate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT