pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Magnetic Resonance Imaging (MRI) With Hyperpolarized Pyruvate (13C) as Diagnostic Tool in Advanced Prostate Cancer
Status: RECRUITING
Conditions: Prostate Cancer|Advanced Prostate Carcinoma
Interventions: DRUG: Hyperpolarized C13|PROCEDURE: Magnetic Resonance Imaging (MRI)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of a Peer-led Educational Intervention Based on Theory of Planned Behavior on Substance Use Intentions and Behaviors Among Secondary School Students of Dessie and Kombolcha Town, Northeast Ethiopia.
Status: COMPLETED
Conditions: Substance Use
Interventions: BEHAVIORAL: a peer-led educational intervention based on theory of planned behavior on substance use intentions and behaviors
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: RFMN in Combination With 1927 nm Thulium Laser for Treating Photoaged Skin
Status: RECRUITING
Conditions: Photoaging
Interventions: DEVICE: radiofrequency microneedling combined with 1927 nm thulium laser|DEVICE: radiofrequency microneedling monotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility of Identifying Brain Mechanisms of Qigong and Behavioral Outcomes After Qigong Practice in People With Chronic Low Back Pain
Status: RECRUITING
Conditions: Low Back Pain
Interventions: BEHAVIORAL: Qigong Exercise|BEHAVIORAL: P.Volve Exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study to Evaluate the Effect of Micardis® / MicardisPlus® on Metabolic Parameters in Patients With Essential Hypertension and Diabetes Mellitus
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Micardis®|DRUG: MicardisPlus®
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study to Evaluate the Safety, Tolerability and Pharmacokinetics of GSK2269557 Administered Via the ELLIPTA Dry Powder Inhaler to Healthy Subjects
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: GSK2269557 ELLIPTA DPI|DRUG: Placebo ELLIPTA DPI|DRUG: Activated charcoal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Activity and Risk Profile of Ponatinib in Chronic Phase Patients With Chronic Myeloid Leukemia Resistant to Imatinib
Status: UNKNOWN
Conditions: Chronic Myeloid Leukemia|Chronic Phase|Adults
Interventions: DRUG: Ponatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Supraorbital Pressure Versus Jaw Thrust for Assessing the Adequate Depth of Anesthesia for LMA Insertion in Children
Status: COMPLETED
Conditions: Laryngeal Masks
Interventions: OTHER: Supraorbital pressure|OTHER: Jaw thrust maneuver
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: A Phase 1 Trial of OPB-111077 in Combination With Bendamustine and Rituximab in Patients With r/r DLBCL
Status: ACTIVE_NOT_RECRUITING
Conditions: Relapsed or Refractory Diffuse Large B-cell Lymphoma
Interventions: DRUG: OPB-111077|DRUG: OPB-111077
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Modified Perichondral Approach Thoracoabdominal Nerve Block and Transversus Abdominal Plane Block in Analgesia Management Following Caesarean Section Surgery
Status: RECRUITING
Conditions: Cesarean Section
Interventions: OTHER: Modified Perichondral Approach Thoracoabdominal Nerve Block|OTHER: Transversus Abdominal Plane Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Subcutaneous Continuous Infusion of Interferon Alfa-2b and Ribavirin in Hepatitis C Genotype 1 Nonresponders
Status: COMPLETED
Conditions: Chronic Hepatitis C
Interventions: DRUG: interferon alfa-2b|DRUG: interferon alfa-2b|DRUG: interferon alfa-2b
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Nebulized Hypertonic Saline and Epinephrine in Hospitalized Infants With Bronchiolitis
Status: COMPLETED
Conditions: Bronchiolitis
Interventions: OTHER: 3% hypertonic saline solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Development of De-novo Stress Urinary Incontinence After Stage II-III Pelvic Organ Prolapse Surgery
Status: COMPLETED
Conditions: Pelvic Organ Prolapse
Interventions: PROCEDURE: sacrospinous ligament fixation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prophylaxis of Diarrhea in Adult Cancer Patients Receiving Targeted Cancer Therapy
Status: COMPLETED
Conditions: Cancer Therapy-Related Diarrhea|Chemotherapy-related Diarrhea|Adult Solid Tumor|Prophylaxis of Diarrhea|Symptomatic Relief of Diarrhea|Targeted Therapy-related Diarrhea
Interventions: DRUG: Crofelemer 125 MG [Mytesi]|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Complete Cytoreduction Followed by IP and Systemic Chemotherapies for Gastric Cancer With Peritoneal Carcinomatosis
Status: RECRUITING
Conditions: Gastric Cancer|Peritoneal Carcinomatosis
Interventions: OTHER: CRS followed by IP and systemic chemotherapies
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mini Versus Conventional Cardiopulmonary Bypass In CABG in Asian Patients
Status: COMPLETED
Conditions: Acute Kidney Injury|Neurological Injury
Interventions: DEVICE: Utilization of the mini CPB circuit|DRUG: Utilization of the conventional circuit
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Correlation Between VCL, AC and Spread of Intrathecal Hyperbaric Bupivacaine in the Term Parturient
Status: UNKNOWN
Conditions: Effects of; Anesthesia, Spinal and Epidural, in Pregnancy
Interventions: PROCEDURE: subarachnoid block
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Compare the Skin Barrier Repair Function of Two Ceramide Containing Moisturizers
Status: UNKNOWN
Conditions: CeraVe Moisturising Lotion
Interventions: DRUG: Ceramides
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Trial Exploring the Opportune Administration of Nab-paclitaxel in the First Line Treatment, Camrelizumab Combined With Nab-paclitaxel and Famitinib, of TNBC.
Status: RECRUITING
Conditions: Triple-Negative Breast Cancer
Interventions: DRUG: Camrelizumab plus Famitinib with/without nab-Palitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Uveitic Macular Edema Treated With Ranibizumab or Steroids
Status: WITHDRAWN
Conditions: Macular Edema|Uveitis
Interventions: DRUG: triamcinolone|DRUG: ranibizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Regarding Renal Function of Everolimus in Combination With Specific Standard Immunosuppressive Regimen Lung Transplant Recipients
Status: COMPLETED
Conditions: Lung Transplantation
Interventions: DRUG: standard therapy|DRUG: Everolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ipilimumab Combined With a Stereotactic Radiosurgery in Melanoma Patients With Brain Metastases
Status: COMPLETED
Conditions: Melanoma|Brain Metastasis
Interventions: DRUG: IPILIMUMAB|RADIATION: Stereotactic radiosurgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial to Assess the Pharmacokinetics, Safety, and Tolerability of Centanafadine in Pediatric Subjects With Attention-deficit/Hyperactivity Disorder
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: DRUG: Centanafadine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oxidized Cellulose hEmostAsis evaluatioN
Status: COMPLETED
Conditions: Intra-operative Bleeding
Interventions: DEVICE: Oxidized cellulose strip|DEVICE: Oxidized regenerated cellulose strip
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Early Signs of Efficacy Study With Riociguat in Adult Homozygous Delta F508 Cystic Fibrosis Patients
Status: TERMINATED
Conditions: Cystic Fibrosis
Interventions: DRUG: Riociguat (Adempas, BAY63-2521)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Role of Host-microbiota Interplay in Hidradenitis Suppurativa Pathogenesis
Status: NOT_YET_RECRUITING
Conditions: Hidradenitis Suppurativa (HS)
Interventions: DIAGNOSTIC_TEST: Skin Swab & Skin Biopsies & Blood Sample
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of TBI-1301 (NY-ESO-1 T Cell Receptor Gene Transduced Autologous T Lymphocytes) in Patients With Synovial Sarcoma
Status: COMPLETED
Conditions: Synovial Sarcoma
Interventions: BIOLOGICAL: TBI-1301|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Window of Opportunity Study of Black Raspberry for Patients With HNSCC
Status: NOT_YET_RECRUITING
Conditions: Squamous Cell Carcinoma of the Oral Cavity or Oropharynx
Interventions: DRUG: Black Raspberry
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Increasing Doses of CKD-516 in Patients With Advanced Solid Cancers
Status: COMPLETED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: CKD-516 inj.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Topical Ketorolac Versus Placebo for Improving Visual Outcomes Following Multifocal IOL Implantation
Status: COMPLETED
Conditions: Macula Thickening
Interventions: DRUG: Prednisolone Acetate|DRUG: Ketorolac 0.4%|DRUG: Gatifloxacin 0.3%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose:
Clinical trial: Prophylactic Uterosacral Ligament Suspension at the Time of Hysterectomy for Prevention of Vaginal Vault Prolapse
Status: UNKNOWN
Conditions: Prolapse of Vaginal Vault After Hysterectomy
Interventions: PROCEDURE: uterosacral ligament suspension colpopexy bilateral
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Decitabine in Treating Patients With Unresectable Lung or Esophageal Cancer or Malignant Mesothelioma of the Pleura
Status: COMPLETED
Conditions: Esophageal Cancer|Lung Cancer|Malignant Mesothelioma|Metastatic Cancer
Interventions: DRUG: decitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Stellate Ganglion Block in Patients Diagnosed With Parkinson's Disease
Status: NOT_YET_RECRUITING
Conditions: Parkinson Disease
Interventions: BEHAVIORAL: Rehabilitation therapy|PROCEDURE: Stellate ganglion block|DRUG: Lidocaine hydrochloride|PROCEDURE: Placebo injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Different Doses of SAR110894 on Cognition in Patients With Mild to Moderate Alzheimer's Disease on Donepezil
Status: COMPLETED
Conditions: Dementia Alzheimer's Type
Interventions: DRUG: SAR110894|DRUG: placebo (for SAR110894)|DRUG: Donepezil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ketamine-Assisted PsychoTherapy ViAbility in Treating Cancer-related Emotional Distress
Status: WITHDRAWN
Conditions: Cancer-related Problem/Condition|Depressive Symptoms|Anxiety Disorders
Interventions: DRUG: Ketamine 100 MG/ML
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Perioperative Electroacupuncture on Postoperative Analgesia in Prostatectomy
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: DRUG: Tramadol|DRUG: Ketamine|DRUG: Tramadol|DRUG: Morphine|PROCEDURE: sedation|PROCEDURE: rescue analgesia|DRUG: Parecoxib|DRUG: paracetamol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Early Phase 2 Clinical Study of TS-142 in Patients With Insomnia Disorder
Status: COMPLETED
Conditions: Insomnia Disorder
Interventions: DRUG: TS-142|DRUG: Dose-matched Placebo to TS-142
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of Methoxyflurane With Periprostatic Local Anaesthesia to Reduce the Discomfort of TRUS B
Status: COMPLETED
Conditions: Cancer
Interventions: DRUG: Methoxyflurane|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Long Term Follow-up of the TREOCAPA Study (TREOCAPA-LT)
Status: RECRUITING
Conditions: Patency of the Ductus Arteriosus Acetaminophen Extreme Prematurity
Interventions: OTHER: 2 year follow-up of neurodevelopment using a parental questionnaire
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of Golimumab in the Treatment of Indian Participants With Active Spondyloarthropathy of Ankylosing Spondylitis or Psoriatic Arthritis
Status: COMPLETED
Conditions: Spondylitis, Ankylosing|Arthritis, Psoriatic
Interventions: DRUG: Golimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Yellow 560 Microscope for Intraoperative Visualization of Fluorescein Stained Intracranial Lesions
Status: TERMINATED
Conditions: Adult Intracranial Neoplasm|Vascular: Intracranial
Interventions: DRUG: Fluorescein Sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testing BVD-523FB (Ulixertinib) as Potentially Targeted Treatment in Cancers With Genetic Changes (MATCH - Subprotocol Z1L)
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Lymphoma|Advanced Malignant Solid Neoplasm|Refractory Lymphoma|Refractory Malignant Solid Neoplasm|Refractory Multiple Myeloma
Interventions: PROCEDURE: Biopsy|PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|PROCEDURE: Echocardiography|PROCEDURE: Magnetic Resonance Imaging|PROCEDURE: Radionuclide Imaging|DRUG: Ulixertinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of a Training Program for Self-management of the Substance Addiction Consequences - a Study Protocol
Status: UNKNOWN
Conditions: Substance Related Disorders
Interventions: BEHAVIORAL: ADSProgram - Self management for substance dependence program|BEHAVIORAL: Treatment as usual - Regular nursing consultation on a medication-based program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Multi-stage Urethroplasty With Augmentation Using a Dorsal Graft Inlay Technique Comparing Graft Use in First or Second Stage
Status: RECRUITING
Conditions: Urethra Stenosis|Urethral Stricture
Interventions: PROCEDURE: Multi-stage urethroplasty with graft inlay in first stage|PROCEDURE: Multi-stage urethroplasty with graft inlay in second stage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Characterization of Sympathetic Nerve Activity in Stress Cardiomyopathy
Status: TERMINATED
Conditions: Cardiomyopathy
Interventions: DEVICE: Sympathetic Nerve Activity|BEHAVIORAL: Mental Stress Test (Color Word Test)|DRUG: The Modified Oxford Technique for Baroreflex Sensitivity|OTHER: Cold Pressor Test|DEVICE: Echocardiographic evaluation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Intraperitoneal Ropivacaine Nebulization for Pain Control After Laparoscopic Surgery
Status: COMPLETED
Conditions: Laparoscopic Cholecystectomy
Interventions: DRUG: Ropivacaine 50 mg|DRUG: Ropivacaine 100 mg|DRUG: Ropivacaine 150 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prenatal Molecular Characterisation by CGH+SNP-ARRAY of Supernumerary Marker Chromosomes and de Novo Apparently Balanced Reciprocal Translocations
Status: TERMINATED
Conditions: Pre-natal Patient
Interventions: OTHER: Blood samples
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Protocol Phototherapy Treatment for Fibromyalgia and Temporomandibular Joint Dysfunction
Status: UNKNOWN
Conditions: Pain|Quality of Life
Interventions: RADIATION: Group Phototherapy|RADIATION: Phototherapy + Physical activity|OTHER: Physical activity|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Safety of Corticosteroids in Combination With Ruxolitinib in the Management of Checkpoint Inhibitor Pneumonia
Status: RECRUITING
Conditions: Severe Checkpoint Inhibitor Pneumonitis
Interventions: DRUG: Corticosteroids|DRUG: Corticosteroids and Ruxolitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of LY3875383 in Healthy Participants and Participants With Hypertriglyceridemia
Status: COMPLETED
Conditions: Hypertriglyceridemia
Interventions: DRUG: LY3875383|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: KYSA-1: A Study of Anti-CD19 Chimeric Antigen Receptor T-Cell (CD19 CAR T) Therapy, in Subjects With Refractory Lupus Nephritis
Status: RECRUITING
Conditions: Lupus Nephritis|Lupus Nephritis - World Health Organization (WHO) Class III|Lupus Nephritis - WHO Class IV
Interventions: BIOLOGICAL: KYV-101 anti-CD19 CAR-T cell therapy|DRUG: Standard lymphodepletion regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Docetaxel in Treating Children With Recurrent Solid Tumors
Status: COMPLETED
Conditions: Brain and Central Nervous System Tumors|Neuroblastoma|Sarcoma
Interventions: BIOLOGICAL: filgrastim|DRUG: docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Glucagon Receptor Inhibition to Enable Breast Cancer Patients to Benefit From PI3K Inhibitor Therapy (REMD-477)
Status: TERMINATED
Conditions: Hyperglycemia Drug Induced
Interventions: BIOLOGICAL: REMD-477
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EPVent 2- A Phase II Study of Mechanical Ventilation Directed by Transpulmonary Pressures
Status: COMPLETED
Conditions: Acute Respiratory Distress Syndrome
Interventions: OTHER: Esophageal-pressure guided mechanical ventilation|OTHER: High PEEP mechanical ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Burst Spinal Cord Stimulation (Burst-SCS) Study
Status: RECRUITING
Conditions: Pain, Chronic|Failed Back Surgery Syndrome
Interventions: DEVICE: Burst-SCS|DEVICE: Sham SCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Awareness-Based Education Given to Individuals With Substance Use Disorder on Self-Efficacy Perception
Status: COMPLETED
Conditions: Nurse's Role|Self Efficacy|Substance Use Disorders
Interventions: OTHER: Psychoeducation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of Vitamin D Therapy on Morbidity and Moratlity in Patients With SARS-CoV 2 Infection
Status: COMPLETED
Conditions: Covid19|SARS-CoV Infection
Interventions: DRUG: Cholecalciferol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study Of Safety And Efficacy Of Ertugliflozin (PF-04971729, MK-8835) In Participants With Type 2 Diabetes (MK-8835-016)
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Placebo to Ertugliflozin|DRUG: Ertugliflozin 1 mg|DRUG: Ertugliflozin 5 mg|DRUG: Ertugliflozin 25 mg|DRUG: Sitagliptin 100 mg|DRUG: Placebo to Sitagliptin|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Hyaluronic Acid as a Therapeutic Strategy for Bone Repair in Human
Status: COMPLETED
Conditions: Alveolar Bone Loss
Interventions: DRUG: hyaluronic acid|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of CPX-351 (Vyxeos™) With Quizartinib for the Treatment of FLT3-ITD Mutation-Positive Acute Myeloid Leukemia
Status: TERMINATED
Conditions: Leukemia, Myeloid, Acute
Interventions: DRUG: CPX-351|DRUG: Quizartinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Ibrutinib in Combination With Revlimid/Dexamethasone in Relapsed/Refractory Multiple Myeloma
Status: ACTIVE_NOT_RECRUITING
Conditions: Refractory Multiple Myeloma|Multiple Myeloma in Relapse|Multiple Myeloma
Interventions: DRUG: Ibrutinib|DRUG: Lenalidomide|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevalence of SARS-CoV-2 Genome in Tears of Asymptomatic and Moderately Symptomatic COVID-19 Patients
Status: TERMINATED
Conditions: SARS-CoV-2
Interventions: DIAGNOSTIC_TEST: conjunctival swab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Research Study to See How Well CagriSema Helps People in East Asia With Excess Body Weight Lose Weight
Status: RECRUITING
Conditions: Obesity or Overweight
Interventions: DRUG: Cagrilintide|DRUG: Semaglutide|DRUG: Placebo Semaglutide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: RCT of Pulp Capping Over Carious Exposure in Adults
Status: COMPLETED
Conditions: Carious Exposure|Human Permanent First and Second Molars|Mature Teeth|Proximal Caries|Healthy Pulp|Reversible Pulpitis
Interventions: PROCEDURE: Direct pulp capping with Dycal|PROCEDURE: Direct pulp capping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of HLX07 in nsqNSCLC Patients With High EGFR Expression
Status: UNKNOWN
Conditions: HLX07, nsqNSCLC, High EGFR Expression
Interventions: DRUG: HLX07+carboplatin+pemetrexed|DRUG: HLX07+docetaxel|DRUG: HLX07
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Odiparcil For The Prevention Of Venous Thromboembolism
Status: COMPLETED
Conditions: Deep Vein Thrombosis|Fibrillation, Atrial|Venous Thromboembolism|Pulmonary Embolism
Interventions: DRUG: Odiparcil|DRUG: Warfarin|DRUG: Coumadin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Comparing Anastrozole-Placebo to the Combination Anastrozole-ZD1839 in Postmenopausal Patients With Estrogen Receptor and/or Progesterone Receptor Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Gefitinib|DRUG: Anastrozole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety of ASP2408 After Subcutaneous Administration to Healthy Male Subjects
Status: COMPLETED
Conditions: Healthy|Pharmacokinetics of ASP2408
Interventions: DRUG: ASP2408|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Easy Access to Smoking Cessation for People Receiving Opioid Agonist Therapy Who Are Smoking Tobacco
Status: ACTIVE_NOT_RECRUITING
Conditions: Smoking Cessation|Substance-Related Disorders
Interventions: DRUG: Nicotine patch|DRUG: Nicotine gum|DRUG: Nicotine lozenge|BEHAVIORAL: Smoking cessation counselling|OTHER: Screening for use of tobacco products|OTHER: Screening for interest in smoking cessation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Healthy School Start Plus Intervention Study
Status: COMPLETED
Conditions: Prevention|Overweight and Obesity|Dietary Habits|Physical Activity|Parent-Child Relations
Interventions: BEHAVIORAL: A Healthy School Start Plus intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of BiCision® Versus UltraCision® During Laparoscopic Supracervical Hysterectomy (LASH)
Status: COMPLETED
Conditions: Uterine Bleeding Disorders|Benign Uterine Conditions|Focus: Comparison of Two Instruments
Interventions: DEVICE: BiCision®|DEVICE: Ultracision® Har-monic Scalpel(Ethicon)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nexium Capsules Helicobacter Pylori Specific Clinical Experience Investigation
Status: COMPLETED
Conditions: Gastric Ulcer|Duodenal Ulcer|Gastric Mucosa-associated Lymphoid Tissue (MALT)|Lymphoma Idiopathic Thrombocytopenic Purpura|Early Gastric Cancer
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: PERSEUS: Preliminary Efficacy and Safety of Cenicriviroc in Adult Participants With Primary Sclerosing Cholangitis
Status: COMPLETED
Conditions: Primary Sclerosing Cholangitis
Interventions: DRUG: Cenicriviroc 150 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Use of Neuromuscular Electrical Stimulation to Reverse Muscle Atrophy in Patients With Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: OTHER: Neuromuscular electrical stimulation|OTHER: Volitional exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hypercapnia: Cognitive Effects and Monitoring
Status: COMPLETED
Conditions: Hypercapnia|Exercise|Nitrogen Narcosis|Diving|Immersion
Interventions: OTHER: NO exercise at depth|OTHER: exercise at depth
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Stony Brook University Calm-Mom Study
Status: COMPLETED
Conditions: Pregnancy Related|Stress, Psychological|Anxiety|Perinatal Depression
Interventions: BEHAVIORAL: SMART Mom|BEHAVIORAL: Mama Support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: To Assess TOTUM-854 on Blood Pressure in Subjects With Moderately Elevated Blood Pressure
Status: RECRUITING
Conditions: Elevated Blood Pressure
Interventions: DIETARY_SUPPLEMENT: Totum-854|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Phase I/II Study of Avelumab in Pediatric Cancer Participants
Status: TERMINATED
Conditions: Refractory or Relapsed Solid Tumors|Lymphoma
Interventions: DRUG: Avelumab|DRUG: Avelumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vaccine Therapy, Interleukin-2, and Sargramostim in Treating Patients With Advanced Tumors
Status: COMPLETED
Conditions: Breast Cancer|Esophageal Cancer|Gastric Cancer|Lung Cancer|Pancreatic Cancer|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: BIOLOGICAL: ALVAC-CEA vaccine|BIOLOGICAL: aldesleukin|BIOLOGICAL: sargramostim|BIOLOGICAL: vaccinia-CEA vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Study on the Effect of Incentive Spirometer-based Respiratory Training on the Long COVID-19
Status: NOT_YET_RECRUITING
Conditions: COVID-19 Pandemic|Diabetes|Hypertension|Cardiac Disease|Long COVID
Interventions: BEHAVIORAL: Incentive Spirometer respiratory training
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Open Label Phase II Pharmacokinetic and Pharmacodynamic Assessment of the Potential for QTc Prolongation Following First Induction Treatment With CPX-351 (Cytarabine:Daunorubicin) Liposome Injection in Acute Leukemias and MDS Patients
Status: COMPLETED
Conditions: Acute Myeloid Leukemia (AML)|Acute Lymphoblastic Leukemia (ALL)|Myelodysplastic Syndrome (MDS)
Interventions: DRUG: CPX-351
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Determining the Impact of Penicillin in Latent RHD: The GOAL Trial
Status: UNKNOWN
Conditions: Rheumatic Heart Disease in Children|Latent Rheumatic Heart Disease|Rheumatic Heart Disease|Heart Diseases
Interventions: DRUG: intramuscular benzathine penicillin G (BPG) prophylaxis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of SSGJ-613 in Gout Subjects Initiating Urate-Lowering Treatment.
Status: ACTIVE_NOT_RECRUITING
Conditions: Gout Arthritis
Interventions: DRUG: Recombinant Anti-IL-1β Humanized Monoclonal Antibody Injection 100 mg|DRUG: Recombinant Anti-IL-1β Humanized Monoclonal Antibody Injection 200 mg|DRUG: Colchicine 0.5 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Urokinase Therapy in Patients With Diabetic Foot Syndrome
Status: TERMINATED
Conditions: Diabetic Foot|Arterial Occlusive Disease|Ischemia
Interventions: PROCEDURE: standard therapy|DRUG: Urokinase
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lean Body Mass as a Determinant of Docetaxel Pharmacokinetics and Toxicity
Status: COMPLETED
Conditions: Breast Cancer|Metastatic Castration-resistant Prostate Carcinoma
Interventions: OTHER: Lean body mass|OTHER: Total body weight|OTHER: bloodsampling
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical Trial of Group ACYW135 Meningococcal Polysaccharide Vaccine 001
Status: COMPLETED
Conditions: Meningitis
Interventions: BIOLOGICAL: Group ACYW135 Meningococcal Polysaccharide Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of a Multi-strain Probiotic Formulation on Immune Response to Influenza Vaccination
Status: COMPLETED
Conditions: Influenza Vaccine
Interventions: DIETARY_SUPPLEMENT: Food Supplement|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: The Benefit/Risk Profile of AOP2014 in Low-risk Patients With PV
Status: COMPLETED
Conditions: Polycythemia Vera
Interventions: DRUG: AOP2014|PROCEDURE: Phlebotomies|DRUG: ASA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimising Microsurgical Reconstruction After Advanced Head and Neck Cancers
Status: UNKNOWN
Conditions: Head and Neck Cancer
Interventions: BEHAVIORAL: Early ambulation|BEHAVIORAL: Early oral feeding|OTHER: Multimodal opioid-sparing analgesia|PROCEDURE: Goal-directed fluid therapy|PROCEDURE: CAD/CAM system for reconstructive plates|OTHER: Functional discharge criteria|OTHER: Standard/historical postoperative regimen
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Amino Acid Concentrations in Serum After Intake of Different Protein Sources
Status: RECRUITING
Conditions: Postprandial Amino Acid Concentrations in Healthy Adults
Interventions: DIETARY_SUPPLEMENT: Protein products
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect of Different Types of Plant-Based Fiber in a Protein-Containing Meal During Satiety and Hunger States
Status: COMPLETED
Conditions: Appetitive Behavior|Satiety
Interventions: DIETARY_SUPPLEMENT: Yoghurt|DIETARY_SUPPLEMENT: Chickpea+Yoghurt|DIETARY_SUPPLEMENT: Oat+Yoghurt
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Interest Of Renal Elastography In Children As A Diagnostic Tool Of Renal Fibrosis: Confrontation To Histological Features Of Renal Biopsies
Status: COMPLETED
Conditions: RENAL FIBROSIS
Interventions: PROCEDURE: Elastography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Connective Tissue Graft Versus a Porcine-derived Membrane (Mucoderm) After Immediate Placement
Status: ACTIVE_NOT_RECRUITING
Conditions: Immediate Implants
Interventions: DEVICE: Dental implant placement, bone and soft tissue augmentation on buccal site
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: InnFocus MicroShunt Versus Trabeculectomy Study
Status: COMPLETED
Conditions: Primary Open Angle Glaucoma
Interventions: PROCEDURE: Glaucoma Surgery|DEVICE: InnFocus MicroShunt
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Nursing-Driven Primary Palliative Care for Urban-Dwelling African Americans With Chronic Lung Disease
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: OTHER: Telehealth Integrated Primary Care (TIPC)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Impact of Medication Therapy Management Intervention on Treatment Outcomes and Medication Adherence Among Adult Patients Comorbid With Diabetes Mellitus and Hypertension at Outpatient Clinics
Status: COMPLETED
Conditions: Diabetes Mellitus|Hypertension
Interventions: OTHER: Medication Therapy Management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: The Assessment of Volume Status by BIA and Lung Ultrasound in Septic AKI Patients Undergoing CRRT
Status: UNKNOWN
Conditions: Septic Acute Kidney Injury
Interventions: PROCEDURE: Fluid management by the value of over hydration in Bioelectrical impedance|PROCEDURE: Fluid management by clinical-based ultrafiltration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: As Low As Reasonable Achievable Fluoroscopy for SVT Ablation
Status: COMPLETED
Conditions: Symptomatic Supraventricular Tachycardia
Interventions: PROCEDURE: SVT ablation by ALARA protocol|PROCEDURE: SVT ablation by conventional protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Interventions for Enhancing Adherence to Syphilis Treatment and Follow-up: Study Protocol for the Health Information and Monitoring of Sexually Transmitted Infections (SIM) Randomized Controlled Trial
Status: UNKNOWN
Conditions: Syphilis
Interventions: BEHAVIORAL: follow-up by telephone|BEHAVIORAL: follow-up via a game in a smartphone app|BEHAVIORAL: conventional follow-up by a health professional
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing the Effects of Water Temperature and Actives in Glucose Solution on Pregnant Women
Status: COMPLETED
Conditions: Gestational Diabetes Mellitus
Interventions: DIAGNOSTIC_TEST: oral glucose tolerance test using water at room temperature|DIAGNOSTIC_TEST: oral glucose tolerance test using hot water|DIAGNOSTIC_TEST: oral glucose tolerance test using cold water|DIAGNOSTIC_TEST: oral glucose tolerance test using hot water with tea bag|DIAGNOSTIC_TEST: oral glucose tolerance test using room temperature water with tea bag|DIAGNOSTIC_TEST: oral glucose tolerance test using cold water with tea bag|DIAGNOSTIC_TEST: Oral glucose tolerance test using bubble water at room temperature|DIAGNOSTIC_TEST: Oral glucose tolerance test using bubble water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: N-acetylcysteine for Tobacco Smoking
Status: UNKNOWN
Conditions: Tobacco Smoking|Oxidative Stress|Inflammation
Interventions: DRUG: N-acetylcysteine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Long-Term Follow-up Study for Non-Hodgkin's Lymphoma Patients Who Received Study Treatment (Plerixafor or Placebo) in the AMD3100-3101 Study (NCT00103610).
Status: COMPLETED
Conditions: Non-Hodgkin's Lymphoma|Autologous Transplantation
Interventions: DRUG: granulocyte colony-stimulating factor (G-CSF)|DRUG: plerixafor|DRUG: Placebo
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study Of Generalized Anxiety Disorder
Status: COMPLETED
Conditions: Anxiety Disorder|Anxiety Disorders
Interventions: DRUG: Paroxetine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Metabolic Control Before and After Supplementation With Lactobacillus Reuteri DSM 17938 in Type 2 Diabetes Patients
Status: COMPLETED
Conditions: Type 2 Diabetes|Insulin Resistance
Interventions: DIETARY_SUPPLEMENT: Lactobacillus reuteri DSM 17938
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Posterior Implant-Supported Modified Monolithic Zirconia and Metal-Ceramic Single Crowns: 5 Years Study
Status: RECRUITING
Conditions: Posterior Occlusion|Fracture
Interventions: DEVICE: modified monolithic zirconia crowns|DEVICE: Metal Ceramic crowns
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: The 1200 Patients Project: Studying the Implementation of Clinical Pharmacogenomic Testing
Status: RECRUITING
Conditions: Patients Undergoing Routine Health Care|Heart Diseases|Inflammatory Bowel Diseases|Autoimmune Disease|Inflammatory Disease|Blood Coagulation Disorders|Hepatitis C|Non-Metastatic Neoplasm
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Drug Interaction Study of Levoketoconazole and Metformin
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: Metformin 500 mg Oral Tablet|DRUG: Levoketoconazole 150 - 600 mg (BID)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effects of Oxytocin on Negative Symptoms and Social Cognition in Schizophrenia and Its Possible Mechanisms
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Oxytocin|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I/II Open-Label, Dose Escalation Study To Determine The Maximum Tolerated Dose And To Evaluate The Safety Profile of Lenalidomide (Revlimid® CC-5013) With Liposomal Doxorubicin In Subjects With Advanced Ovarian and Primary Peritoneal Carcinoma
Status: TERMINATED
Conditions: Ovarian Cancer
Interventions: DRUG: CC-5013|DRUG: liposomal doxorubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GSH Supplementation on Cold/Flu Symptoms in Older Healthy Adults
Status: WITHDRAWN
Conditions: Improvement in Immune Cell Function in Elderly Humans
Interventions: DIETARY_SUPPLEMENT: Setria glutathione supplement|DIETARY_SUPPLEMENT: Crystalline Cellulose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Clinical Usefulness of Digital Single-operator Cholangioscopy(SpyGlass™) for Post-liver Transplant Anastomotic Stricture
Status: RECRUITING
Conditions: Liver Transplant; Complications|Biliary Duct Obstruction|Anastomosis, Obstructed
Interventions: DEVICE: digital single-operator cholangioscopy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: PD-1 Antibody SHR-1210 in Patients With Relapsed or Refractory Classic Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Hodgkin Lymphoma, Adult
Interventions: DRUG: SHR-1210
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of PD01 on Cardiovascular Health and Microbial Environment
Status: COMPLETED
Conditions: Overweight|Obesity
Interventions: DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: PD01
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Chinese First Episode Schizophrenia's Optimal Dynamic Antipsychotic Treatment Regime
Status: UNKNOWN
Conditions: Schizophrenia
Interventions: DRUG: Olanzapine|DRUG: Risperidone|DRUG: Aripiprazole|DRUG: Amisulpride|DRUG: Paliperidone long-acting injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Safety and Immune Response to an HIV Vaccine Boost Following the Administration of Two HIV Vaccines, in HIV-Uninfected, Healthy Adults (Study Extension to HVTN 073/SAAVI 102)
Status: COMPLETED
Conditions: HIV Infections
Interventions: BIOLOGICAL: Sub C gp140 Vaccine|BIOLOGICAL: MF59C.1 Adjuvant|OTHER: Sodium chloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy of Enteric-coated Mycophenolate Sodium (EC-MPS) Plus Valsartan in Patients With Kidney Transplants (MYTHOS
Status: COMPLETED
Conditions: De Novo Renal Transplantation
Interventions: DRUG: Enteric-coated Mycophenolate sodium (EC-MPS), valsartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION