pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Skin Sympathetic Nerve Activity and Cardiac Arrhythmia
Status: COMPLETED
Conditions: Sudden Death|Ventricular Tachycardia|Persistent Atrial Fibrillation
Interventions: DEVICE: SKNA recording
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Oral Microbiota as Reservoir for Systemic Opportunistic Pathogens
Status: COMPLETED
Conditions: COPD Exacerbation|Pulmonary Disease, Chronic Obstructive|Dental Plaque
Interventions: PROCEDURE: Dental cleaning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Pazopanib and Pemetrexed in Advanced Non-small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer, Non-Small Cell
Interventions: DRUG: pazopanib and pemetrexed|DRUG: pemetrexed and cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Synflutide HFA Inhaler and Seretide Evohaler in Healthy Volunteers With Charcoal Block
Status: COMPLETED
Conditions: Asthma|Chronic Obstructive Pulmonary Disease (COPD)
Interventions: DRUG: Fluticasone propionate|DRUG: Salmeterol (as xinafoate)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Neuromuscular Training Versus Traditional Exercise on Balance and Fall in Geriatric Population With Fall Risk
Status: RECRUITING
Conditions: Geriatric
Interventions: DIAGNOSTIC_TEST: Neuromuscular Training|DIAGNOSTIC_TEST: Traditional Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Cytarabine and Daunorubicin With or Without Gemtuzumab Ozogamicin in Treating Older Patients With Acute Myeloid Leukemia or Myelodysplastic Syndromes
Status: COMPLETED
Conditions: Leukemia|Myelodysplastic Syndromes
Interventions: DRUG: cytarabine|DRUG: daunorubicin hydrochloride|DRUG: gemtuzumab ozogamicin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Laminaria and Misoprostol for Cervical Preparation Before Second Trimester Surgical Abortion
Status: COMPLETED
Conditions: Induced; Abortion, Nonmedical
Interventions: DEVICE: Laminaria, MedGyn Products, Inc. USA.|DRUG: Misoprostol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ropivacaine Plasma Concentration With or Without Epinephrine for Posterior Quadratus Lumborum Block
Status: COMPLETED
Conditions: Local Anesthetic Systemic Toxicity|Anesthesia, Local
Interventions: DRUG: Epinephrine / Ropivacaine|DRUG: Ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TLIP Block Versus Modified TLIP Block for Posterior Decompression and Stabilization Surgery
Status: COMPLETED
Conditions: Analgesia|Surgical Procedure, Unspecified
Interventions: PROCEDURE: Thoracolumbar Interfascial Plane block|PROCEDURE: Modified Thorcolumbar Interfascial Plane block
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Strict Versus Permissive Thresholds for Initiation of Pharmacotherapy in Gestational Diabetes (START 2)
Status: NOT_YET_RECRUITING
Conditions: Gestational Diabetes|Pregnancy Related
Interventions: DRUG: Insulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Blockade of Vascular Potassium Channels During Human Endotoxemia
Status: COMPLETED
Conditions: Endotoxemia
Interventions: DRUG: endotoxin|DRUG: Potassium channel blockers: TEA, Quinin, Tolbutamide|DRUG: L-NMMA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fetoscopic Open Spina Bifida Repair Using the SAFER Technique
Status: COMPLETED
Conditions: Open Spina Bifida|Myelomeningocele|Meningomyelocele|Chiari Malformation With Spina Bifida|Chiari Malformation Type 2
Interventions: OTHER: Neuropsicomotor developmental test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Clinical Trial to Compare the Pharmacokinetics and Safety of "BR1016A" With "BR1016B" in Healthy Volunteers
Status: COMPLETED
Conditions: Chronic Heart Failure
Interventions: DRUG: BR1016A|DRUG: BR1016B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Different Extended Release (ER)-Formulations and Multiple Ascending Dosing of AZD3241
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: AZD3241|DRUG: Placebo Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: COX-2 Inhibitor to Prevent Post-ERCP Pancreatitis
Status: UNKNOWN
Conditions: Pancreatitis, Acute
Interventions: DRUG: Cox-2|DRUG: Indomethacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Norwegian Study of Oral Cladribine and Rituximab in Multiple Sclerosis (NOR-MS)
Status: RECRUITING
Conditions: Relapsing Multiple Sclerosis|Multiple Sclerosis
Interventions: BIOLOGICAL: Rituximab|DRUG: Cladribine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Isolating and Testing Circulating Tumor DNA and Soluble Immune Markers During the Course of Treatment for Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer|Lung Neoplasms|Cancer of Lung|Cancer of the Lung|Neoplasms, Lung|Neoplasms, Pulmonary|Pulmonary Cancer|Pulmonary Neoplasms|Carcinoma, Non-small-cell Lung|Adenocarcinoma|Squamous Cell Carcinoma
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pinaverium Bromide in Post-cholecystectomy Sphincter of Oddi Dysfunction
Status: UNKNOWN
Conditions: Sphincter of Oddi Dysfunction
Interventions: DRUG: Danshu Capsules|DRUG: Pinaverium Bromide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Analysis of Changes in Medication Prescriptions After Hospitalization for 4 Disciplines: Gerontology, Diabetology, Cardiology and Rheumatology: Medical, Pharmaceutical and Economic Aspects
Status: UNKNOWN
Conditions: Diabetes|Cardiac Disease|Rheumatic Diseases
Interventions: OTHER: collection of prescription data
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Piroxicam Addition During Arthrocentesis on Mouth Opening and Postoperative Pain
Status: COMPLETED
Conditions: Temporomandibular Joint Disorders
Interventions: PROCEDURE: arthrocentesis with lactate ringer only|PROCEDURE: arthrocentesis with lactate ringer followed by injection with piroxicam 2 ml (40mg)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Two Physiotherapy's Approaches in Chronic Low Back Pain: Is Addressing Psychosocial Factors Beneficial?
Status: COMPLETED
Conditions: Low Back Pain, Recurrent
Interventions: OTHER: Physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Determine the Safety and Immunogenicity of Bivalent GI.1 and GII.4 Vaccines in Healthy Volunteers
Status: ACTIVE_NOT_RECRUITING
Conditions: Norovirus Infections
Interventions: DRUG: Open label Bivalent GII.4/GI.1 high dose vaccine 2×10 to the power 11 IU/dose|DRUG: Bivalent GII.4/GI.1 high dose vaccine 2×10 to the power 11 IU/dose|DRUG: Bivalent GII.4/GI.1 medium dose vaccine 1×10 to the power 11 IU/dose|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: S1+ Paclitaxel (IV&IP) + Bevacizumab (IP) Versus S1+Oxaliplatin as First-line Treatment in Gastric Cancer With Malignant Ascites
Status: UNKNOWN
Conditions: Metastatic Gastric Adenocarcinoma
Interventions: DRUG: S1|DRUG: Paclitaxel|DRUG: Bevacizumab|DRUG: Oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Etanercept in Active RA Despite Methotrexate Therapy in Japan
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: ETN Alone|DRUG: ETN+MTX
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Bioavailability of Tazarotene Foam, 0.1%, and Tazorac Gel, 0.1%, in Subjects With Acne Vulgaris
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: Tazarotene|DRUG: Tazaroc Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Disseminating and Implementing a Smoking Cessation Program for Pregnant and Postpartum Women
Status: COMPLETED
Conditions: Smoking|Tobacco Use Disorder
Interventions: BEHAVIORAL: brief pre-delivery smoking cessation counseling|BEHAVIORAL: additional pre-delivery smoking cessation counseling|BEHAVIORAL: post- delivery smoking cessation counseling|BEHAVIORAL: incentives
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Qinggongshoutao Bolus in aMnestic Mild Cognitive Impairment
Status: COMPLETED
Conditions: Mild Cognitive Impairment|Herbal Medicine Allergy
Interventions: DRUG: Qinggongshoutao Bolus|DRUG: Ginkgo Biloba Extract 761|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Oral Probiotics on Oral Hygiene and Halitosis in Orthodontic Patients.
Status: COMPLETED
Conditions: Halitosis|Probiotics|Orthodontic Appliance Complication
Interventions: DIETARY_SUPPLEMENT: Prodilac Oral, Frezyderm|DIETARY_SUPPLEMENT: placebo lozenges
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Triathlon Tritanium Cone Augments Outcomes Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Arthroplasty|Replacement|Knee
Interventions: DEVICE: Triathlon Tritanium Cone Augments
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Intraoperative Pulmonary Nodules Localization Guided by Virtual Reality Technology
Status: WITHDRAWN
Conditions: Lung Neoplasm
Interventions: DEVICE: LungBrella marker implantation and VATS partial lobe resection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pantoprazole With Doxorubicin for Advanced Cancer Patients With Extension Cohort of Patients With Solid Tumours
Status: COMPLETED
Conditions: Advanced Solid Tumours
Interventions: DRUG: pantoprazole sodium for injection|DRUG: doxorubicin hydrochloride injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of Improved BEAM Conditioning Regimen for ASCT in Lymphoma
Status: NOT_YET_RECRUITING
Conditions: Lymphoma|Autologous Hematopoietic Stem Cell Transplantation
Interventions: DRUG: Improved BEAM regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility Study for the Determination of Oxysterols in Patients With Breast Cancer Receiving Hormonal Therapy With Tamoxifen or Not
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Tamoxifen,|DRUG: Exemestane|DRUG: Anastrozole|DRUG: Letrozole
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single Agent Versus Combination Chemotherapy to Treat High-risk Elderly With Non-small Cell Lung Cancer
Status: TERMINATED
Conditions: Carcinoma, Non-small Cell Lung
Interventions: DRUG: Carboplatin|DRUG: Nab-paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Performance and Safety of Hyalo Gyn Gel on the Treatment of Vaginal Atrophy in Postmenopausal Women
Status: COMPLETED
Conditions: Vulvovaginal Atrophy
Interventions: DEVICE: Hyalo Gyn gel in prefilled applicators
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Prebent Plates and Custom Plates After le Fort 1 in Orthognathic Surgery
Status: COMPLETED
Conditions: Orthognathic Surgery
Interventions: PROCEDURE: Orthognathic surgery (lefort1)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fronto-parietal tDCS in Severely Brain Injured Patients With Disorders of Consciousness
Status: COMPLETED
Conditions: Vegetative State|Minimally Conscious State|Disorders of Consciousness
Interventions: DEVICE: Anodal tDCS|DEVICE: Sham tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Biofreeze on Post Manipulation Soreness in Patients With Mechanical Neck Pain
Status: COMPLETED
Conditions: Neck Pain
Interventions: DRUG: BioFreeze|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Improving Aphasia Using Electrical Brain Stimulation
Status: RECRUITING
Conditions: Stroke|Aphasia
Interventions: DEVICE: Active transcranial direct current stimulation (tDCS)|DEVICE: Sham transcranial direct current stimulation (tDCS)|BEHAVIORAL: Language Specific Attention Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Effects of Chronobiology-guided Lifestyle Interventions on Insomnia Severity, Cognitive Performance, and Sleepiness
Status: RECRUITING
Conditions: Circadian Rhythm Sleep Disorder
Interventions: BEHAVIORAL: Chronobiology-guided lifestyle interventions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: The Effect of Boceprevir in Russian Participants Diagnosed With Chronic Hepatitis C Genotype 1 (P08160)
Status: COMPLETED
Conditions: Chronic Hepatitis C Genotype 1
Interventions: DRUG: Boceprevir|DRUG: Placebo|BIOLOGICAL: peginterferon alfa-2b|DRUG: Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Effect of Protein Prescription Strategies on Nitrogen Balance and Upshots in Critically Ill Patients
Status: COMPLETED
Conditions: Critical Illness|Malnutrition|Protein
Interventions: OTHER: Two differnt protien prescription (ig per kg per day and 2g per kg /day )will be assigned to each group interventional
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety and Immunogenicity of GSK Biologicals' Malaria Vaccine 257049 When Administered on 7 Schedules to African Infants
Status: COMPLETED
Conditions: Malaria
Interventions: BIOLOGICAL: GSK Biological's Investigational Malaria Vaccine 257049|BIOLOGICAL: Engerix-B|BIOLOGICAL: Tritanrix HepB Hib|BIOLOGICAL: BCG|BIOLOGICAL: OPV|BIOLOGICAL: Rouvax
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Relative Bioavailability of 1 mg and 10 mg BI 1356 BS as Powder in the Bottle (PIB) to 1 mg and 10 mg BI 1356 BS as Tablets as Single Oral Administration in Healthy Male Volunteers Including the Influence of Food on the Bioavailability of 10 mg BI 1356 BS
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BI 1356 BS PIB - low dose|DRUG: BI 1356 BS tablet - low dose|DRUG: BI 1356 BS PIB - high dose|DRUG: BI 1356 BS tablet - high dose|DRUG: BI 1356 BS tablet - high dose with food
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety Study to Determine the Maximum Tolerated Dose of Elesclomol Sodium in Patients With Solid Tumors
Status: SUSPENDED
Conditions: Metastatic Solid Tumors
Interventions: DRUG: Elesclomol Sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Value-Driven Study on Reducing Immune Checkpoint Inhibitor Dosing Frequency in Advanced Cancers
Status: NOT_YET_RECRUITING
Conditions: Carcinoma, Hepatocellular|Gastric Adenocarcinoma|GastroEsophageal Cancer|Oesophageal Cancer|Non-small Cell Lung Cancer|Head and Neck Squamous Cell Carcinoma
Interventions: DRUG: Extended Dosing Interval - A|DRUG: Extended Dosing Interval - B|DRUG: Extended Dosing Interval - C|DRUG: Standard of Care - A|DRUG: Standard of Care - B|DRUG: Standard of Care - C
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Biometrics and Self-reported Health Changes in Adults Receiving Behavioral Treatments for Chronic Pain
Status: NOT_YET_RECRUITING
Conditions: Chronic Pain|Sedentary Time
Interventions: BEHAVIORAL: Cognitive Behavioral Therapy|BEHAVIORAL: Acceptance and Commitment Therapy (ACT)|BEHAVIORAL: Moderate to high Intensity Group Exercise
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study to Evaluate the Effect of Naltrexone and Bupropion Extended-Release Combination on Cardiac Repolarization in Healthy Participants
Status: COMPLETED
Conditions: Heart Repolarization
Interventions: DRUG: Naltrexone HCl/bupropion HCl|OTHER: Placebo|DRUG: Moxifloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Lung Deflation in Pediatric Subclavian Vein Catheterization
Status: COMPLETED
Conditions: Pediatric Subclavian Vein Catheterization
Interventions: PROCEDURE: lung deflation|PROCEDURE: lung inflation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Carbetocin Versus Oxytocin in Caesarean Section for the Control of Postpartum Haemorrhage
Status: UNKNOWN
Conditions: Postpartum Haemorrhage
Interventions: DRUG: Carbetocin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Pharmacokinetic (PK) and Pharmacodynamic (PD) Study of CD 2027 Spray in Adults With Plaque-type Psoriasis
Status: COMPLETED
Conditions: Plaque-type Psoriasis
Interventions: DRUG: CD 2027
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Efficacy and Safety of OxabactTM on Reduction of Urinary Oxalate in Primary Hyperoxaluria Patients
Status: COMPLETED
Conditions: Primary Hyperoxaluria
Interventions: BIOLOGICAL: Oxalobacter formigenes|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Safety and Efficacy Study of JNJ-42165279 in Participants With Social Anxiety Disorder
Status: COMPLETED
Conditions: Phobic Disorders
Interventions: DRUG: JNJ-42165279|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Cost Effectiveness of Malaria Diagnosis Procedures and the Rational Use of ACT in Zanzibar
Status: COMPLETED
Conditions: Malaria
Interventions: DEVICE: Rapid Diagnostic Test for P. falciparum malaria
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Randomized Controlled Clinical Study of Biplanar Ultrasound-guided Puncture of Lumbar Interforamen
Status: COMPLETED
Conditions: Lumbar Disc Herniation|Percutaneous Endoscopic Lumbar Discectomy|Three-dimension Ultrasound|Learning Curves
Interventions: DEVICE: Real-time 3D Xplane ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study of Tremelimumab and IV Durvalumab Plus Poly-ICLC in Subjects With Biopsy-accessible Cancers
Status: COMPLETED
Conditions: Head and Neck Squamous Cell Carcinoma|Breast Cancer|Sarcoma|Merkel Cell Carcinoma|Cutaneous T-Cell Lymphoma|Melanoma|Renal Cancer|Bladder Cancer|Prostate Cancer|Testicular Cancer|Solid Tumor
Interventions: DRUG: Durvalumab|DRUG: Tremelimumab|DRUG: Poly-ICLC
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cont. of a Study to Evaluate Implanting Peripheral Nerve Grafts Into Subjects With Parkinson's Disease (PD) During DBS
Status: ACTIVE_NOT_RECRUITING
Conditions: Parkinson's Disease
Interventions: PROCEDURE: Autologous Peripheral Nerve Graft
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Claims-based Algorithm for the Identification of Transthyretin-mediated Amyloidosis (ATTR) Amyloidosis in Medical Records
Status: RECRUITING
Conditions: Transthyretin Amyloidosis
Interventions: DEVICE: Computer algorithm for ATTR
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: The Impact of Milk-products Differing in Their Glycaemic Properties on the Behaviour of Infants
Status: UNKNOWN
Conditions: Mood Behaviour|Cognitive Function
Interventions: OTHER: Low Glycaemic index growing up milk|OTHER: High GI growing up milk
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Evaluation Comparing Tau PET Radiotracers, [18F]GTP1 and [18F]PI-2620 or [18F]MK-6240 in Subjects With Normal Cognition or Prodromal to Moderate Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer Disease (AD)
Interventions: DRUG: [18F]GTP1|DRUG: [18F]PI-2620|DRUG: [18F]MK-6240
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation of Maintenance With Bortezomib Plus Daratumumab (V-Dara) After Induction With Bortezomib, Melphalan, Prednisone Plus Daratumumab (VMP-Dara) in Newly Diagnosed Multiple Myeloma (MM) Patients Non-eligible for autoSCT
Status: RECRUITING
Conditions: Multiple Myeloma|Non-eligible for Autologous Stem Cell Transplantation (ASCT)
Interventions: DRUG: Bortezomib|DRUG: Daratumumab
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety, and Efficacy of a New Buccal Film of Montelukast in Patients With Mild to Moderate Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer Disease
Interventions: DRUG: Montelukast buccal film|OTHER: Placebo buccal film
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Collection of Whole Blood Samples for the Evaluation of Preeclampsia (Pre-E) Biomarkers From Pregnant Women
Status: UNKNOWN
Conditions: Pre-Eclampsia|Hypertension|Proteinuria in Pregnancy|Thrombocytopenia|Renal Insufficiency|Impaired Liver Function|Pulmonary Edema|Headache|Visual Impairment
Interventions: OTHER: Non-interventional study
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Azithromycin in the Prevention of Lung Injury in Premature Newborn
Status: COMPLETED
Conditions: Bronchopulmonary Dysplasia
Interventions: DRUG: Azithromycin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Intrathecal Autologous Adipose-derived Mesenchymal Stromal Cells for Amyotrophic Lateral Sclerosis (ALS)
Status: ACTIVE_NOT_RECRUITING
Conditions: ALS|Amyotrophic Lateral Sclerosis
Interventions: DRUG: Autologous Adipose-derived Mesenchymal Stromal Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pretreatment of Patients Expecting Bariatric Surgery With the GLP-1 Analogon Liraglutid
Status: TERMINATED
Conditions: Obesity
Interventions: DRUG: GLP-1 (Liraglutide)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Conversion From Brand to Generic Tacrolimus in High Risk Transplant Recipients
Status: COMPLETED
Conditions: Complication of Transplant
Interventions: DRUG: Prograf|DRUG: Tacrolimus, Sandoz|DRUG: Tacrolimus, Reddy Laboratory|DRUG: Tacrolimus, Mylan|DRUG: Tacrolimus, Accord|DRUG: Tacrolimus, Pancea Biotech Limited
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nerve Ablation by Cooled Radiofrequency Compared to Corticosteroid Injection for Management of Knee Pain
Status: COMPLETED
Conditions: Osteoarthritis of the Knee
Interventions: DEVICE: Cooled Radiofrequency|DRUG: Corticosteroid injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study-Quantitative Analysis of Positional Fatty Acids in Postprandial Chylomicron Triacylglycerol Using 13C NMR Spectroscopy
Status: UNKNOWN
Conditions: Healthy
Interventions: OTHER: Palm olein vs Lard
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Efficacy and Safety Study of Two Doses of Apremilast (CC-10004) In Japanese Patients With Moderate-To-Severe Plaque-Type Psoriasis
Status: COMPLETED
Conditions: Psoriasis|Psoriatic Arthritis|Psoriasis Arthropatica
Interventions: DRUG: Apremilast|DRUG: Apremilast|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Study of Physiological vs Right Ventricular Pacing in Patients With Normal Ventricular Function Post TAVI
Status: RECRUITING
Conditions: Transcatheter Aortic Valve Implantation|Physiological Pacing|Right Ventricular Pacing|AV Block|Preserved Left Ventricular Systolic Function
Interventions: PROCEDURE: Conduction system pacing|PROCEDURE: Right ventricular pacing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neuromuscular Electrical Stimulation on Humeral Adductors in Subjects With Rotator Cuff Tear: an Observational Study
Status: RECRUITING
Conditions: Rotator Cuff Tears
Interventions: DEVICE: novel brace with neuromuscular electrical stimulation|BEHAVIORAL: scapular and adductor exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing the Effects of Insulin Glargine on Blood Glucose Between Needle-free Jet Injection and Insulin Pen
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DEVICE: The needle-free jet injector|DEVICE: Conventional insulin pen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: QT Interval Abnormalities in Sulfonylurea Treated Type 2 Diabetes: Relationship to Treatment Induced Hypoglycaemia
Status: COMPLETED
Conditions: Diabetes Related Complications
Interventions: DEVICE: Holter and Glucose monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Breathing Training and Exercise Capacity in Non-CFB
Status: RECRUITING
Conditions: Non-cystic Fibrosis Bronchiectasis
Interventions: DEVICE: LungTrainers|BEHAVIORAL: LungTrainers Pulmonary Rehabilitation regime
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pemetrexed Plus Cetuximab in Patients With Recurrent Non Small Cell Lung Cancer
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: Pemetrexed|DRUG: Cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigation of U1-A Uterine Anomalies Implantation Markers From the Lateral Walls of the Endometrium
Status: UNKNOWN
Conditions: T-Shaped Uterus|Infertility, Female|Genital Tract Anomalies
Interventions: DEVICE: Bipolar cutting electrode (26040 BL1 Karl Storz, Tuttlingen)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tocilizumab Versus Methylprednisolone in the Cytokine Release Syndrome of Patients With COVID-19
Status: TERMINATED
Conditions: Cytokine Release Syndrome|Covid-19
Interventions: DRUG: Tocilizumab 180 MG/ML|DRUG: Methylprednisolone Sodium Succinate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RPCRC Validation Study
Status: UNKNOWN
Conditions: Multivariate Risk Assessment for ISUP ≥2 Prostate Cancer
Interventions: OTHER: Assessment of the diagnostic performance of the PI-RADS score (as a stand-alone) and of the RPCRC for predicting the presence of ISUP ≥2 prostate cancer at subsequent biopsy in 251 patients.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Attention, Teleconferencing and Social Anxiety
Status: COMPLETED
Conditions: Social Anxiety Disorder
Interventions: BEHAVIORAL: Experimental: Attention Guidance + Exposure|BEHAVIORAL: Active Comparator: Exposure Alone|BEHAVIORAL: Experimental: Attention Control + Exposure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tri Staple Technology Stapler Used in Gastric Bypass
Status: COMPLETED
Conditions: Sleep Apnea|Hypertension|Hyperlipidemia|Coronary Artery Disease|Gastroesophageal Reflux Disease|Osteoarthritis|Diabetes
Interventions: DEVICE: Tri Staple Technology stapler
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study on The Effect of Multiple Dose Carbamazepine on Single Dose Pharmacokinetics of RO4917838 in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: RO4917838|DRUG: carbamazepine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Decompressive Craniectomy In Malignant Middle Cerebral Artery Infarcts
Status: TERMINATED
Conditions: Malignant Middle Cerebral Artery Infarction
Interventions: PROCEDURE: Decompressive hemicraniectomy and duraplasty|PROCEDURE: hemicraniectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Determining Optimal Free Dose Combination of Tiotropium Bromide and BI 1744 CL in Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: olodaterol (BI 1744) low|DRUG: low tiotropium bromide|DRUG: olodaterol (BI 1744) high|DRUG: medium tiotropium bromide|DRUG: high tiotropium bromide|DRUG: Placebo|DEVICE: Respimat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Assessing the Efficacy of Sirolimus in Patients With COVID-19 Pneumonia for Prevention of Post-COVID Fibrosis
Status: RECRUITING
Conditions: Pulmonary Fibrosis|COVID-19 Pneumonia|Long COVID
Interventions: DRUG: Sirolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Oncolytic Virus (OVV-01) Injection in the Treatment of Patients With Advanced Solid Tumors
Status: RECRUITING
Conditions: Neoplasms
Interventions: DRUG: oncolytic virus (OVV-01) injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open Label Study Evaluating the Efficacy and Safety of JUVÉDERM VOLUMA™ XC for the Facial Temporal Regions
Status: COMPLETED
Conditions: Aging
Interventions: DEVICE: JUVÉDERM VOLUMA™ XC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Renal Allograft Tolerance Through Mixed Chimerism (Belatacept)
Status: COMPLETED
Conditions: Kidney Failure, Chronic|Renal Insufficiency
Interventions: DRUG: Belatacept|DRUG: ATG|DRUG: Rituximab|RADIATION: Total Body Irradiation|RADIATION: Thymic Irradiation|PROCEDURE: Combined Bone Marrow/Kidney Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vaccination With Autologous Breast Cancer Cells Engineered to Secrete Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF) in Metastatic Breast Cancer Patients
Status: COMPLETED
Conditions: Breast Cancer
Interventions: BIOLOGICAL: Autologous, Lethally Irradiated Breast Cancer Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study of Use of Calcium Channel Blocker to Decrease Inflammation and Pain in Hereditary Pancreatitis
Status: COMPLETED
Conditions: Pancreatitis
Interventions: DRUG: amlodipine (drug)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial on No-touch Vein Graft (NT-graft) in Coronary Surgery
Status: ACTIVE_NOT_RECRUITING
Conditions: Ischemic Heart Disease
Interventions: PROCEDURE: No touch technique|PROCEDURE: Control technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Clinical Study of Carrimycin on Treatment Patients With COVID-19
Status: UNKNOWN
Conditions: Novel Coronavirus Infectious Disease (COVID-19)
Interventions: DRUG: Carrimycin|DRUG: lopinavir/ritonavir tablets or Arbidol or chloroquine phosphate|DRUG: basic treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Nemolizumab in PN
Status: COMPLETED
Conditions: Prurigo Nodularis
Interventions: DRUG: CD14152 Dose A|DRUG: CD14152 placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Genomic Investigation of Unusual Responders
Status: RECRUITING
Conditions: Cancer|Breast Cancer|Non-small Cell Lung Cancer|Colorectal Cancer|Genitourinary Cancer|Gynecological Cancer|Upper Aerodigestive Tract Cancer|Pancreatobiliary Gastrointestinal Cancer|Melanoma (Skin)|Rare Cancer|Carcinoma of Unknown Primary
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Enteric-coated Mycophenolate Sodium Versus Mycophenolate Mofetil in Adult de Novo Renal Transplant Patients
Status: COMPLETED
Conditions: Renal Transplant
Interventions: DRUG: Mycophenolate sodium (enteric coated)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Cardioinhibitory Reflex Syncope. Permanent Pacemaker Therapy or Cardioneuroablation?
Status: RECRUITING
Conditions: Reflex Syncope
Interventions: PROCEDURE: Cardioneuroablation|DEVICE: Permanent pacemaker therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prolonged Grief and Perception of Femininity in Gynecological Cancer Patients
Status: COMPLETED
Conditions: Cervix Cancer|Uterine Cancer|Ovarian Cancer|Endometrial Cancer|Vulva Cancer|Grief|Femininity
Interventions: BEHAVIORAL: Such as art therapy, play therapy, breathing techniques
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy of Lactose-free Milk in Treating Acute Gastroenteritis in Infants
Status: RECRUITING
Conditions: Acute Gastroenteritis
Interventions: DIETARY_SUPPLEMENT: Lactose-free milk formula (Frisolac LF ®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Web-based Interpretation Training For Anxiety
Status: COMPLETED
Conditions: Anxiety
Interventions: BEHAVIORAL: Positive Cognitive Bias Modification - Interpretation|BEHAVIORAL: 50/50 Cognitive Bias Modification - Interpretation|BEHAVIORAL: Anxious Imagery Prime|BEHAVIORAL: Neutral Imagery Prime
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 3 Study to Evaluate the Efficacy and Safety of Elafibranor Versus Placebo in Patients With Nonalcoholic Steatohepatitis (NASH)
Status: TERMINATED
Conditions: Nonalcoholic Steatohepatitis (NASH) With Fibrosis
Interventions: DRUG: Elafibranor|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Kidney and Hematopoietic Cell Transplants Using a Regimen to Promote Hematopoietic Cell Engraftment
Status: ENROLLING_BY_INVITATION
Conditions: Immune Tolerance
Interventions: BIOLOGICAL: Combined Deceased Donor Kidney and Hematopoietic Cell Transplants
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Digital App and Platform for Supporting Medicines Control and Optimization in Older Individuals With Heart Failure
Status: COMPLETED
Conditions: Heart Failure
Interventions: OTHER: Digital App and Platform for Supporting Medicines Control and Optimizationin Older Individuals With Heart Failure
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Safety and Efficacy Study of BBI-4000 in Subjects With Axillary Hyperhidrosis
Status: COMPLETED
Conditions: Hyperhidrosis
Interventions: DRUG: BBI-4000 Gel, 5%|DRUG: BBI-4000 Gel, 10%|DRUG: BBI-4000 Gel, 15%|DRUG: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Feelings Club: Evaluating a School-based Intervention for Children at Risk for Depression and Anxiety Disorders
Status: COMPLETED
Conditions: Anxiety|Depression
Interventions: BEHAVIORAL: Cognitive Behavioral Therapy|BEHAVIORAL: School-based CBT|BEHAVIORAL: activity control condition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Modafinil Augmentation Therapy for Excessive Daytime Sleepiness and Negative Symptoms in Patients With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Modafinil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Isolate and Test Circulating Tumor Cells Using the ClearCell® FX EP+ System
Status: COMPLETED
Conditions: Lung Cancer|Lung Neoplasms|Cancer of Lung|Cancer of the Lung|Neoplasms, Lung|Neoplasms, Pulmonary|Pulmonary Cancer|Pulmonary Neoplasms|Carcinoma, Non-small-cell Lung|Adenocarcinoma|Squamous Cell Carcinoma
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Stereotactic Body Radiation Therapy and Vertebroplasty in Treating Patients With Localized Spinal Metastasis
Status: COMPLETED
Conditions: Metastatic Cancer|Pain|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: RADIATION: radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Two Way Crossover Closed Loop Study MPC vs FMPD
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: DEVICE: FMPD AP algorithm|DEVICE: MPC AP system|DEVICE: Dexcom G6 Continuous Glucose Monitoring (CGM) System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of RC28-E Versus Aflibercept in Diabetic Macular Edema
Status: RECRUITING
Conditions: Diabetic Macular Edema
Interventions: BIOLOGICAL: RC-28E|BIOLOGICAL: Aflibercept
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Cardiac Ultrasound Evaluation of Two Types of Weaning Trials of Mechanical Ventilation for a First Weaning Trial
Status: COMPLETED
Conditions: Critical Care|Weaning of Mechanical Ventilation|Trans-thoracic Echocardiography|Mitral Doppler|Diastolic Function
Interventions: OTHER: trans thoracic echocardiography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Experiential Classroom on Establishing Healthy Behaviors During Pregnancy
Status: RECRUITING
Conditions: Experiential Classroom|Health Behavior|Preconception Education|Adverse Pregnancy Outcome
Interventions: BEHAVIORAL: Experiential Classroom
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: ENhanced Recovery in CHildren Undergoing Surgery
Status: RECRUITING
Conditions: Inflammatory Bowel Disease|Crohn's Disease|Ulcerative Colitis
Interventions: PROCEDURE: Perioperative surgical care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Tolerability/PoP Study in Allergic Rhinitis After Intranasal Administration of AZD8848
Status: COMPLETED
Conditions: Allergic Rhinitis
Interventions: DRUG: AZD8848|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Anti-Cytokine Therapy for Vasculitis
Status: COMPLETED
Conditions: Wegener's Granulomatosis|Renal Limited Vasculitis|Microscopic Polyangiitis
Interventions: BIOLOGICAL: Infliximab|DRUG: Cyclophosphamide|DRUG: Prednisolone|DRUG: Azathioprine|PROCEDURE: Plasma exchange|DRUG: Mycophenolate mofetil|DRUG: Methylprednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Tolerance and Efficacy of Mitoxantrone Hydrochloride Liposome Injection Combined With Cytarabine in Patients With Acute Myeloid Leukemia (AML)
Status: UNKNOWN
Conditions: Treatment-naive or Relapsed or Refractory Acute Myeloid Leukemia (AML)
Interventions: DRUG: Mitoxantrone Hydrochloride liposome injection|DRUG: Cytarabine (LoDAC)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TELI COM - Telithromycin in Children With Otitis Media
Status: TERMINATED
Conditions: Otitis Media, Suppurative|Otitis Media, Purulent
Interventions: DRUG: Telithromycin|DRUG: Azithromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of a Multicomponent Intervention on Cognitive Function for the Caregiver-patient Dyad
Status: NOT_YET_RECRUITING
Conditions: Mild Cognitive Impairment
Interventions: OTHER: Multi-component, transdisciplinary and multifocal intervention for the cognition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT