pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Efficacy and Safety of Low-dose Laser Acupuncture on Treating Insomnia Associated With Major Depressive Disorder
Status: NOT_YET_RECRUITING
Conditions: Major Depressive Disorder|Insomnia
Interventions: DEVICE: Low-Dose Laser Acupuncture (LLA)|DEVICE: Sham Laser Acupuncture (SLA)|DRUG: Standard Medication Management (Control Group)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Provenge® (Sipuleucel-T) Active Cellular Immunotherapy Treatment of Metastatic Prostate Cancer After Failing Hormone Therapy
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: BIOLOGICAL: Sipuleucel-T|BIOLOGICAL: APC-Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Replacing Starchy Vegetables and Refined Grains With Beef on Cardio-metabolic Disease Risk Factors (S53)
Status: COMPLETED
Conditions: Diet Modification
Interventions: OTHER: Controlled healthy vegetarian diet|OTHER: Controlled beef diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Impatto Emodinamico Dell'Anestesia Subaracnoidea Titrata Versus Tecnica Single-shot Nei Pazienti Sottoposti ad Artroprotesi d'Anca. RCT
Status: COMPLETED
Conditions: Anesthesia; Adverse Effect|Anesthesia, Local
Interventions: PROCEDURE: subarachnoid block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Comparison of Ondansetron, Metoclopramide and Promethazine for the Treatment of Nausea and Vomiting in the Adult ED
Status: TERMINATED
Conditions: Nausea
Interventions: DRUG: Ondansetron|DRUG: Metoclopramide|DRUG: Promethazine|DRUG: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I/II Study of Human Anti-Cytomegalovirus (CMV) Monoclonal Antibody MSL-109 in Newborns With Symptomatic Congenital CMV Infection Without Central Nervous System Disease
Status: COMPLETED
Conditions: Cytomegalovirus Infections
Interventions: DRUG: SDZ MSL-109
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Palliative Care in Spinal Muscular Atrophy (SMA) 1
Status: COMPLETED
Conditions: Spinal Muscular Atrophy 1
Interventions: OTHER: Follow-up diary and questionnaire
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study Protocol of Online DBT-Mindfulness Intervention in Multiple Sclerosis
Status: RECRUITING
Conditions: Multiple Sclerosis
Interventions: BEHAVIORAL: Online DBT-Mindfulness Intervention|BEHAVIORAL: Online psychoeducational intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Nonintubated Thoracic Epidural Anesthesia Versus Double-lumen Intubated Anesthesia in Video-assisted Thoracic Surgery
Status: UNKNOWN
Conditions: Anaesthesia|Video Assisted Thoracic Surgery
Interventions: PROCEDURE: no-intubated thoracic epidural anesthesia|PROCEDURE: double-lumen endotracheal intubated anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ACX-362E [Ibezapolstat] for Oral Treatment of Clostridioides Difficile Infection
Status: COMPLETED
Conditions: Clostridium Difficile Infection
Interventions: DRUG: Ibezapolstat|DRUG: Vancomycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Atezolizumab (MPDL3280A) Compared With a Platinum Agent (Cisplatin or Carboplatin) + (Pemetrexed or Gemcitabine) in Participants With Stage IV Non-Squamous or Squamous Non-Small Cell Lung Cancer (NSCLC) [IMpower110]
Status: COMPLETED
Conditions: Non-Squamous Non-Small Cell Lung Cancer, Squamous Non-Small Cell Lung Cancer
Interventions: DRUG: Atezolizumab (MPDL3280A) [TECENTRIQ], an engineered anti-PDL1 antibody|DRUG: Carboplatin|DRUG: Cisplatin|DRUG: Gemcitabine|DRUG: Pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Controlled Phase 2a Study to Evaluate the Efficacy of EDP-323 Against Respiratory Syncytial Virus Infection in a Virus Challenge Model
Status: RECRUITING
Conditions: RSV Infection
Interventions: DRUG: EDP-323 Dose Regimen 1|DRUG: EDP-323 Dose Regimen 2|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Postoperative Pain Relieve for Patients Undergoing Surgical Treatment of Femoral Fracture
Status: RECRUITING
Conditions: Proximal Femur Fracture
Interventions: DRUG: Intrathecal morphine administration|DRUG: Parenteral administration of analgesics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: F18-PSMA-1007 PET for Early Biochemical Recurrence of Prostate Cancer
Status: UNKNOWN
Conditions: Prostate Cancer Recurrent
Interventions: DIAGNOSTIC_TEST: F18-fluciclovine PET/CT|DIAGNOSTIC_TEST: F18-PSMA-1007 PET/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Hepatectomy Versus Radiofrequency Ablation for Hepatocellular Carcinoma Adjacent to Major Blood Vessels
Status: COMPLETED
Conditions: Hepatocellular Carcinoma
Interventions: PROCEDURE: surgical resection|PROCEDURE: percutaneous radiationfrequency ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Strong Albumin Solutions in Patients With Septic Shock
Status: RECRUITING
Conditions: Sepsis|Septic Shock|Shock, Toxic
Interventions: DRUG: hyperoncotic human albumin solution|DRUG: Buffered crystalloid solutions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multi-center, Comparative Clinical Trial to Evaluate the Efficacy and Safety of Inject BMP in Patients Undergoing Transforaminal Lumbar Interbody Fusion
Status: UNKNOWN
Conditions: Transforaminal Lumbar Interbody Fusion
Interventions: DEVICE: Inject BMP|PROCEDURE: Locally Harvested Bone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Minimal Invasive Procedure for Myocardial Infarction
Status: COMPLETED
Conditions: ST Elevation Myocardial Infarction
Interventions: PROCEDURE: MIMI procedure (two-step strategy)|PROCEDURE: Immediate Stenting (one-step strategy)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Pharmacokinetics of Multiple Ascending Doses of AZD8871 in Healthy Male Japanese Subjects
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease - COPD
Interventions: DRUG: AZD8871|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Paclitaxel vs Paclitaxel + Cetuximab in Recurrent - Metastatic Head & Neck Carcinoma After Failure of a 1º Chemotherapy
Status: TERMINATED
Conditions: Head and Neck Cancer
Interventions: DRUG: Paclitaxel|DRUG: Cetuximab + Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Autologous Adipose Tissue Derived Mesenchymal Stem Cells for Rotator Cuff Disease
Status: COMPLETED
Conditions: Rotator Cuff Disease
Interventions: BIOLOGICAL: Autologous Adipose Tissue Derived MSCs Transplantation|BIOLOGICAL: Autologous Adipose Tissue Derived MSCs Transplantation|BIOLOGICAL: Autologous Adipose Tissue Derived MSCs Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multicenter, Randomized, Double-Blind, Placebo-Controlled Efficacy Study Comparing 4 Weeks of Treatment With Esomeprazole 20 mg qd and 40 mg qd to Placebo qd in Patients With Heartburn and Sleep Disturbances Associated With Gastroesophageal Reflux Disease (GERD)
Status: COMPLETED
Conditions: Gastroesophageal Reflux Disease (GERD)
Interventions: DRUG: Esomeprazole|DRUG: Esomeprazole|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Exercise Fatigue Parameters and Endothelial Function in Pediatric Patients With a History of COVID-19 Infection or MIS-C
Status: UNKNOWN
Conditions: COVID-19|MIS-C Associated With COVID-19
Interventions: DEVICE: Cardiopulmonary exercise test (CPET)|DEVICE: Peripheral Arterial Tonography (PAT) using the EndoPAT™ device|DIAGNOSTIC_TEST: Endothelin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Drug-Drug Interaction Study of GK Activator (2) and Simvastatin in Patients With Type 2 Diabetes.
Status: COMPLETED
Conditions: Diabetes Mellitus Type 2
Interventions: DRUG: GK Activator (2)|DRUG: Simvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Efficacy of Povetacicept in Adults With Immunoglobulin A Nephropathy (IgAN)
Status: NOT_YET_RECRUITING
Conditions: Immunoglobulin A Nephropathy
Interventions: DRUG: Povetacicept|DRUG: Placebo (matched to Povetacicept)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Interferon Gamma-1b by Injection for the Treatment of Patients With Cystic Fibrosis
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: interferon gamma-1b
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of the GORE® EXCLUDER® Conformable AAA Endoprosthesis In the Treatment of Abdominal Aortic Aneurysms
Status: ACTIVE_NOT_RECRUITING
Conditions: Abdominal Aortic Aneurysm (AAA)
Interventions: PROCEDURE: endovascular repair of the AAA
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of Intervention on Impaired Glucose Tolerance(IGT) in Patients With Coronary Heart Disease.
Status: UNKNOWN
Conditions: Coronary Heart Disease|Impaired Glucose Tolerance
Interventions: DRUG: Voglibose tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Slopped Shoulder Implant Neck vs Conventional Implant Neck Design on Crestal Bone Level in the Maxilla
Status: UNKNOWN
Conditions: Missing Tooth
Interventions: OTHER: slopped shoulder implant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: High-yield HIV Testing, Facilitated Linkage to Care, and Prevention for Female Youth in Kenya
Status: COMPLETED
Conditions: HIV|Adolescent Behavior
Interventions: BEHAVIORAL: SMART Randomization 1 - Referral|BEHAVIORAL: SMART Randomization 1 - Referral and SMS|BEHAVIORAL: SMART Randomization 2 - SMS|BEHAVIORAL: SMART Randomization 2 - Incentive|BEHAVIORAL: High Risk Negative Cohort (N=185)|OTHER: All participants. Approximately (N=1200)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Treatment of Children CD19+ Leukemia and Non-Hodgkin Lymphoma With CD19-TriCAR-T/SILK Cell Therapy
Status: UNKNOWN
Conditions: Non-Hodgkin Lymphoma of Intestine|Leukemia
Interventions: BIOLOGICAL: CD19-TriCAR-T/SILK
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Prophylactic Treatment of Oral Prochlorperazine for Acute Mountain Sickness
Status: COMPLETED
Conditions: AMS|Acute Mountain Sickness
Interventions: OTHER: Immediate descent from altitude.|DRUG: Diphenhydramine|DRUG: Prochlorperazine 10 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Laboratory Evaluation of the Humoral Immune Response in Adults and Children to the H1 Hemagglutinin (HA) Stalk Domain and Other Influenza A Virus Protein Epitopes, After Administration of GlaxoSmithKline (GSK) Biologicals' Pandemic Influenza Vaccines
Status: COMPLETED
Conditions: Immunologic Tests
Interventions: OTHER: Serum samples
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of Adalimumab on Inflammatory Mediators Following a Systemic Endotoxin Challenge
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Adalimumab|DRUG: Lipopolysaccharide (LPS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Estrogen for Treating Depression in Menopausal Women With Hot Flashes and Insomnia
Status: COMPLETED
Conditions: Sleep Initiation and Maintenance Disorders|Depression
Interventions: DRUG: Estrogen Replacement Therapy|DRUG: Zolpidem|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility Trial of CBT for Depersonalisation in Psychosis
Status: COMPLETED
Conditions: Psychotic Disorders|Depersonalization
Interventions: OTHER: CBT for Depersonalization/Derealization|OTHER: Treatment as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study of Induction Chemotherapy Followed by Surgery for Locally Advanced Resectable Head and Neck Cancer
Status: TERMINATED
Conditions: Head and Neck Cancer
Interventions: OTHER: radiation combined with weekly carboplatin|PROCEDURE: conservation surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Vaccine Therapy and OPT-821 or OPT-821 Alone in Treating Patients With Ovarian Epithelial Cancer, Fallopian Tube Cancer, or Primary Peritoneal Cancer in Complete Remission
Status: WITHDRAWN
Conditions: Fallopian Tube Cancer|Ovarian Cancer|Primary Peritoneal Cavity Cancer
Interventions: BIOLOGICAL: immunological adjuvant OPT-821|BIOLOGICAL: polyvalent antigen-KLH conjugate vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Pharmacodynamic Evaluation of Stool Output Following Oral Administration of Various Low Volume PEG3350-based Gut Cleansing Solutions Using the Split Dose Intake in Healthy Subjects
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: NER1006|DRUG: NER1006|DRUG: NER1006|DRUG: Moviprep|DRUG: NER1006|DRUG: NER1006|DRUG: NER1006|DRUG: NER1006
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Eccentric Training for Patients With Lateral Epicondylalgia
Status: COMPLETED
Conditions: Tennis Elbow|Epicondylitis, Lateral Humeral
Interventions: OTHER: Eccentric training|DEVICE: Forearm band|DEVICE: Forearm band
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Empowerment Model Towards Type 2 Diabetic Adults To Enhance Vegetable Intake in Achieving Glycemic Control
Status: COMPLETED
Conditions: Glycemic Control for Diabetes Mellitus
Interventions: BEHAVIORAL: Empowerment model to improve dietary intake|OTHER: Control group following conventional approach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy and Safety of Bortezomib as First-line Treatment of Acquired TTP
Status: NOT_YET_RECRUITING
Conditions: Thrombotic Thrombocytopenic Purpura, Acquired
Interventions: DRUG: Bortezomib Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence of Two Ciprofloxacin 0.3%/Dexamethasone 0.1% Sterile Otic Suspensions in Otitis Media in Children With Tympanostomy Tubes
Status: TERMINATED
Conditions: Otitis Media in Patients With Tympanostomy Tubes
Interventions: DRUG: Ciprofloxacin 0.3%/dexamethasone 0.1% sterile otic suspension|DRUG: CIPRODEX® (ciprofloxacin 0.3%/dexamethasone 0.1%)|DRUG: Placebo Sterile Otic Suspension
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Relative Bioavailability of Two Tepotinib Film-Coated Tablet Formulations in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Tepotinib test (Treatment Period 1)|DRUG: Tepotinib reference (Treatment Period 2)|DRUG: Tepotinib reference (Treatment Period 1)|DRUG: Tepotinib test (Treatment Period 2)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Universal Transvaginal Cervical Length Screening Program for Prevention of Preterm Birth in Singletons Without Prior Preterm Birth
Status: UNKNOWN
Conditions: Preterm Birth
Interventions: DIAGNOSTIC_TEST: cervical length screening
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of the Sensitivity of Merz Lips Fullness Assessment Scale Following Etermis 4® Treatment for Lips Volume Augmentation
Status: COMPLETED
Conditions: Subjects Desiring Lip Augmentation
Interventions: DEVICE: Etermis 4®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Botulinum Neurotoxin Type A (BoNT-A) in Paediatric Non-neurogenic Therapy Resistant Overactive Bladder (OAB)
Status: COMPLETED
Conditions: Overactive Bladder|Incontinence, Daytime Urinary|Incontinence, Nighttime Urinary
Interventions: PROCEDURE: Intradetrusor BoNT-A
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Sequencing and Combination of Mirabegron and TTNS in Overactive Bladder Syndrome: a Multicenter, Randomized, Open-label, Crossover Trial
Status: UNKNOWN
Conditions: Overactive Bladder Syndrome
Interventions: DRUG: mirabegron|PROCEDURE: TTNS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cannabidiol, Morphine, Pain
Status: RECRUITING
Conditions: CBD|Chronic Pain
Interventions: DRUG: Immediate-release Oral Morphine Sulfate Tablets|OTHER: Thermal and Pressure Nociceptive Sensitivity
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Multi-Center, Randomized, Double-Masked, Parallel-Group, Vehicle-Controlled, Clinical Trial of Reproxalap to Assess the Safety and Efficacy in Subjects With Dry Eye Disease
Status: COMPLETED
Conditions: Dry Eye
Interventions: DRUG: Reproxalap Ophthalmic Solution (0.25% Novel Formulation) QID to BID|DRUG: Vehicle Ophthalmic Solution (0.25% Novel Formulation) QID to BID
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Effects of Single Ascending Doses of ASP1707 in Healthy Young Japanese Male Subjects
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: ASP1707|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Preemptive and Preventive Acetaminophen/Ibuprofen Fixed-dose Combination After Robot-assisted Radical Prostatectomy
Status: RECRUITING
Conditions: Postoperative Pain
Interventions: DRUG: Acetaminophen/Ibuprofen fixed-dose combination
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Continuous Positive Pressure Versus Bi-level in Overlap Syndrome
Status: UNKNOWN
Conditions: Overlap Syndrome|Nocturnal Hypoventilation
Interventions: DEVICE: Bi-level positive airway pressure with ventilatory support|DEVICE: continuous positive airway pressure without ventilatory support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of MNRP1685A in Combination With Bevacizumab With or Without Paclitaxel in Patients With Locally Advanced or Metastatic Solid Tumors
Status: COMPLETED
Conditions: Solid Cancers
Interventions: DRUG: bevacizumab|DRUG: MNRP1685A|DRUG: paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial to Test for Bioequivalence Between NN1045 and NN5401 in Subjects With Type 1 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 1
Interventions: DRUG: insulin degludec/insulin aspart
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Thoracic Mobility Exercise Versus Manual Release Technique in Minimizing Upper Back Pain
Status: COMPLETED
Conditions: Upper Back Pain
Interventions: OTHER: Thoracic Mobility exercises|OTHER: Manual Release technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Acceptability and Feasibility of an ED-based, Peer-delivered, Suicide Safety Planning Intervention
Status: COMPLETED
Conditions: Suicidal Ideation|Suicide, Attempted|Mental Health Issue
Interventions: OTHER: Peer Supporter Safety Planning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Randomized Controlled Study of the Traditional Percutaneous Coronary Intervention and Intervention Using Optical Coherence Tomography of Incomplete Stent Adhesion and Extent of the Formation of Neointima by Resolute Zotarolimus-eluting Stent Insertion
Status: UNKNOWN
Conditions: Coronary Artery Disease|Stable Angina|Unstable Angina
Interventions: PROCEDURE: percutaneous coronary intervention|PROCEDURE: OCT-guided percutaneous coronary intervention|PROCEDURE: percutaneous coronary intervention|PROCEDURE: OCT-guided percutaneous coronary intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose Response Effects of Inhaled Fluticasone on Airway Effects of Hypertonic-saline in Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Fluticasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Development of Advanced Double Intravenous Vasopressor Automated (ADIVA) System
Status: ACTIVE_NOT_RECRUITING
Conditions: Hypotension|Anesthesia
Interventions: DRUG: Phenylephrine|DRUG: Ephedrine|DEVICE: ADIVA System|DEVICE: DIVA System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Sleep Apnea in Multiple Sclerosis Positive Airway Pressure Trial
Status: COMPLETED
Conditions: Obstructive Sleep Apnea-hypopnea in Multiple Sclerosis Patients
Interventions: DEVICE: Effective continuous positive airway pressure (CPAP)|DEVICE: Sham continuous positive airway pressure (CPAP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Thalidomide, Doxorubicin, and Dexamethasone in Treating Patients With Untreated Stage II or Stage III Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma and Plasma Cell Neoplasm
Interventions: DRUG: dexamethasone|DRUG: doxorubicin hydrochloride|DRUG: thalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: TAP Block Catheters vs Liposomal Bupivacaine for Pain Control After Colorectal Surgery
Status: COMPLETED
Conditions: Colorectal Surgery|TAP Blocks
Interventions: DRUG: Exparel|DRUG: Ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adaptative MR-Guided Stereotactic Body Radiotherapy of Liver Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Radiotherapy
Interventions: RADIATION: Adaptative MR-Guided Stereotactic Body Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study Using Autologous Regulatory T Cell Infusion Zortress (Everolimus) in Renal Transplant Recipients
Status: COMPLETED
Conditions: End Stage Renal Disease|Kidney Transplant
Interventions: DRUG: Treg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Comparing the Use of Laser and of Kinesiotherapy for the Treatment of Female Stress Urinary Incontinence
Status: UNKNOWN
Conditions: Urinary Stress Incontinence
Interventions: PROCEDURE: Laser|PROCEDURE: kinesiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical and Biological Interest of Taxanes in Advanced Squamous Cell Anal Carcinoma
Status: COMPLETED
Conditions: Anal Canal Carcinoma
Interventions: DRUG: Docetaxel, Cisplatin and 5-Fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Transcutaneous Electrostimulation (TENS) on Pain and Physical Function in Patients With Knee Osteoarthritis
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: DEVICE: TENS|DEVICE: Sham TENS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Electrical Impedance Tomography for Optimization of Positive End-Expiratory Pressure: Acute Respiratory Distress Syndrome
Status: COMPLETED
Conditions: Acute Respiratory Distress Syndrome|ARDS
Interventions: OTHER: Usual care|DEVICE: PEEP titration by EIT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Self vs. Physician Application of Triamcinolone-Econazole in Otomycosis
Status: RECRUITING
Conditions: Otomycosis
Interventions: PROCEDURE: physician-applied Triamcinolone Acetonide Econazole Cream|PROCEDURE: patient-applied Triamcinolone Acetonide Econazole Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single-Laser PVI: Single-encirclement Laserballoon Ablation for Pulmonary Veins Isolation
Status: TERMINATED
Conditions: Assessment of Safety of Laser Balloon Ablation|Assessment of Procedural Times of Laser Ballon Ablation
Interventions: OTHER: Laser ballon ablation for Pulmonary vein isolation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Translating ECHOS2 Into an mHealth Platform
Status: COMPLETED
Conditions: Childhood Cancer|Cardiac Toxicity|Pediatric Cancer
Interventions: BEHAVIORAL: Computerized Intervention Authoring Software (CIAS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Activation of Brown Adipose Tissue Metabolism Using Mirabegron
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: Mirabegron|DRUG: Bisoprolol Fumarate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Use of Bone-, Tooth- and Mucosa- Supported Stereolithographic Guides for Dental Implant Placement
Status: COMPLETED
Conditions: Stereolithography|Dental Implants|Prosthesis
Interventions: DEVICE: Mucosa-supported single-type guides|DEVICE: Bone-supported guides|DEVICE: Dental Implants
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of AZD0486 in Subjects With Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma
Status: RECRUITING
Conditions: B-cell Non Hodgkin Lymphoma|Diffuse Large B Cell Lymphoma|High-grade B-cell Lymphoma|Follicular Lymphoma
Interventions: DRUG: AZD0486 IV
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Daylight-mediated Photodynamic Therapy of Actinic Keratoses:Comparing 0.2%HAL With 16%MAL
Status: COMPLETED
Conditions: Actinic Keratoses
Interventions: DRUG: Hexylaminolaevulinate cream|DRUG: Methylaminolaevulinate cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nasal Mask and Prong Use in Non-invasive Ventilation for Newborns
Status: UNKNOWN
Conditions: Bronchopulmonary Dysplasia
Interventions: DEVICE: binasal prongs|DEVICE: nasal mask
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CPT-SMART for Treatment of PTSD and Cigarette Smoking
Status: RECRUITING
Conditions: Smoking|Stress Disorders, Post-Traumatic
Interventions: BEHAVIORAL: Smoking Cessation Cognitive Behavioral Therapy (CBT)|DRUG: Bupropion|BEHAVIORAL: Cognitive Processing Therapy|BEHAVIORAL: Smoking Abstinence Reinforcement Therapy|BEHAVIORAL: Yoked Contingency Management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of New Dentifrices Containing Centella Asiatica and Bamboo Salt on Reducing Plaque and Gingivitis
Status: COMPLETED
Conditions: Labor Trial Refused
Interventions: OTHER: Centella asiatica and bamboo salt|OTHER: Centella asiatica
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of 68Ga-FAPI-46 PET and 18F-FDG PET in Lung Cancer
Status: RECRUITING
Conditions: Lung Cancer
Interventions: DIAGNOSTIC_TEST: 68Ga-FAPI-46
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Robot-assisted Function-sparing Cystectomy Followed by Modified Orthotopic Ileal Neobladder
Status: RECRUITING
Conditions: Negative Surgical Margins
Interventions: PROCEDURE: Prostate and seminal-sparing Cystectomy|PROCEDURE: Conventional Radical Cystoprostatectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hexaminolevulinate (HAL) Photodynamic Therapy (PDT) of Cervical Intraepithelial Neoplasia (CIN) Grade 1
Status: TERMINATED
Conditions: Cervical Intraepithelial Neoplasia
Interventions: DRUG: Hexaminolevulinate (HAL)|DRUG: Placebo|DRUG: Hexaminolevulinate (HAL)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial to Assess the SYNERGY 48 mm Stent System for the Treatment of Atherosclerotic Lesion(s)
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DEVICE: SYNERGY 48 mm
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of a Single Image Guided Injection of CTM for Glenohumeral Arthritis
Status: ACTIVE_NOT_RECRUITING
Conditions: Osteoarthritis Shoulder|Glenohumeral Osteoarthritis|Shoulder Osteoarthritis
Interventions: DEVICE: CTM Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimizing Adherence and Glycemia in Youth With New Insulin-dependent Diabetes Mellitus (IDDM)
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus
Interventions: BEHAVIORAL: Family Teamwork Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Fetal Movement Counting in Third Trimester of Pregnancy
Status: COMPLETED
Conditions: Decreased Fetal Movements, Unspecified Trimester, Other Fetus|Worries|Pregnancy
Interventions: OTHER: Fetal Movement Counting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Zactima With Temodar During Radiation Treatment for Newly Diagnosed Stage IV Brain Tumors
Status: COMPLETED
Conditions: Glioblastoma Multiforme|Gliosarcoma
Interventions: DRUG: ZD6474|DRUG: temozolomide|RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Supporting Understanding of PCOS Education and Research (SUPER) Study
Status: RECRUITING
Conditions: Polycystic Ovary
Interventions: BEHAVIORAL: DASH diet|BEHAVIORAL: Very low-carbohydrate diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Pharmacokinetic Study Comparing EG12014 and Herceptin (Trastuzumab) in Healthy Male Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: BIOLOGICAL: EG12014|BIOLOGICAL: EU-sourced Herceptin|BIOLOGICAL: US-sourced Herceptin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Placebo Controlled Trial With Baclofen for the Treatment of GERD Patients With Incomplete PPI Response
Status: COMPLETED
Conditions: Gastro Esophageal Reflux
Interventions: DRUG: Baclofen|OTHER: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Opicapone in Clinical Practice
Status: COMPLETED
Conditions: Parkinson's Disease With Wearing-off Motor Fluctuations
Interventions: DRUG: BIA 9-1067|DRUG: levodopa/dopa decarboxylase inhibitor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of Audiovisual Intervention
Status: NOT_YET_RECRUITING
Conditions: Parent-Child Relations|Premature; Infant, Light-for-dates|Premature Infant Disease
Interventions: BEHAVIORAL: Audiovisual Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: IL-4(38-37)-PE38KDEL Immunotoxin in Treating Patients With Recurrent Malignant Astrocytoma
Status: UNKNOWN
Conditions: Brain and Central Nervous System Tumors
Interventions: BIOLOGICAL: interleukin-4 PE38KDEL cytotoxin|DRUG: isolated perfusion|PROCEDURE: surgical procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Feasibility of Adaptive Radiation Therapy for Human-papilloma Virus-positive Oropharyngeal Cancer Patients on MRIdian Linac
Status: NOT_YET_RECRUITING
Conditions: Oropharynx Cancer
Interventions: DEVICE: MRIdian Linac
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Extended-Release RANCAD in the Patients With Stable Angina Pectoris
Status: COMPLETED
Conditions: Stable Angina Pectoris
Interventions: DRUG: RANCAD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Induction-Maintenance With Atazanavir in HIV Naïve Patients (The INDUMA Study)
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Atazanavir + 2 NRTIs|DRUG: Atazanavir + Ritonavir + 2 NRTIs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TMC435-TiDP16-C108 - A Study in Healthy Volunteers Investigating the Pharmacokinetic Interaction Between TMC435 and Digoxin and Between TMC435 and Rosuvastatin
Status: COMPLETED
Conditions: Hepatitis C Virus
Interventions: DRUG: Rosuvastatin|DRUG: Rosuvastatin|DRUG: TMC435|DRUG: Digoxin|DRUG: Digoxin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Syringes Replacement for Insulin Application for Pens Device in a Population of Elderly Patients With Type 2 Diabetes: Multifactorial Intervention to Improve Glycemic Control
Status: UNKNOWN
Conditions: Diabetes
Interventions: DEVICE: Pens Device|DEVICE: Syringe|OTHER: Monitoring capillary blood glucose with blood glucose monitor, lancet tapes and capillary blood glucose tests (3 tests/day)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bortezomib, Thalidomide, and Dexamethasone After Melphalan and Stem Cell Transplant in Treating Patients With Stage I-III Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma and Plasma Cell Neoplasm|Neurotoxicity
Interventions: DRUG: bortezomib|DRUG: dexamethasone|DRUG: melphalan|DRUG: thalidomide|GENETIC: cytogenetic analysis|GENETIC: fluorescence in situ hybridization|OTHER: laboratory biomarker analysis|OTHER: questionnaire administration|PROCEDURE: autologous hematopoietic stem cell transplantation|PROCEDURE: peripheral blood stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of RPL554 in Addition to Tiotropium in COPD Patients
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease Moderate
Interventions: DRUG: 1.5 mg RPL554 plus tiotropium|DRUG: 6 mg RPL554 plus tiotropium|DRUG: Placebo plus tiotropium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Internet-delivered Cognitive Behavioral Treatment of Depression and Anxiety in Latin American College Students
Status: ACTIVE_NOT_RECRUITING
Conditions: Major Depressive Disorder|Generalized Anxiety Disorder
Interventions: BEHAVIORAL: Yo Puedo Sentirme Bien- Clinician-Guided version|BEHAVIORAL: Yo Puedo Sentirme Bien- Self-Guided version
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Abraxane and RT for Non-Small Cell Lung Cancer (NSCLC)
Status: WITHDRAWN
Conditions: Non-small Cell Lung Cancer, Stage III
Interventions: RADIATION: radiation therapy|DRUG: Paclitaxel Protein-Bound, and CARBOPLATIN
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Per Oral Endoscopic Myotomy (POEM) and Prolonged Dilatation (PRD) for Achalasia
Status: RECRUITING
Conditions: Esophageal Achalasia
Interventions: PROCEDURE: Endoscopic intervention A|PROCEDURE: Endoscopic intervention B|PROCEDURE: Endoscopic intervention C|PROCEDURE: Laparoscopic Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gallium-68 NODAGA-JR11 PECT/CT in Neuroendocrine Tumors
Status: RECRUITING
Conditions: Neuroendocrine Tumors
Interventions: DRUG: Gallium-68 NODAGA-JR11
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy and Safety of Estradiol and Progesterone Microspheres for the Treatment of Climacteric Symptoms.
Status: COMPLETED
Conditions: Menopause
Interventions: DRUG: Estradiol and Progesterone|DRUG: Estradiol and Progesterone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Doxycycline In Lymphangioleiomyomatosis (LAM)
Status: COMPLETED
Conditions: Lymphangioleiomyomatosis|Tuberous Sclerosis
Interventions: DRUG: Doxycycline|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ibuprofen Versus Acetaminophen for Treatment of Mild Traumatic Brain Injury
Status: WITHDRAWN
Conditions: Brain Concussion
Interventions: DRUG: Ibuprofen|DRUG: Acetaminophen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Empagliflozin Reduces Progression of Diabetic Retinopathy in Patients With High Risk of Diabetic Macular Edema
Status: TERMINATED
Conditions: Diabetes Mellitus, Type II
Interventions: DRUG: Empagliflozin|DRUG: Glimepiride|DRUG: Empagliflozin placebo|DRUG: Glimepiride placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Endovascular Treatment With Versus Without Intravenous rhTNK-tPA in Stroke
Status: RECRUITING
Conditions: Stroke, Acute|Stroke, Ischemic
Interventions: DRUG: rhTNK-tPA|OTHER: Endovascular treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Role of Progesterone in Hypoactive Sexual Desire Disorder in Menopausal Women
Status: UNKNOWN
Conditions: Menopause|Sexual Desire Disorder|Hypoactive Sexual Desire Disorder
Interventions: DEVICE: Vaginal progesterone 8%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of Neuromuscular Blockade on Pulmonary Complications in Elective Cardiac Surgery
Status: COMPLETED
Conditions: Neuromuscular Blockade|Postoperative Complications
Interventions: DRUG: Succinylcholine|DRUG: Cisatracurium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Randomized Trial Investigating Melatonin Supplementation vs Placebo on Sleep Disturbance Following Total Joint Arthroplasty
Status: UNKNOWN
Conditions: Sleep Disturbance|Total Joint Arthroplasty
Interventions: DRUG: melatonin 6mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oxygen Nanobubble Drink Impact on Exercise in Elite Athletes
Status: NOT_YET_RECRUITING
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Oxygen Nanobubble|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Denosumab for Prolonging Bone Metastasis-Free Survival in Men With Hormone-Refractory Prostate Cancer
Status: COMPLETED
Conditions: Castrate-resistant Prostate Cancer
Interventions: BIOLOGICAL: Denosumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Determine the Pharmacokinetics on TPV/r in Subjects With Mild and Moderate Hepatic Insufficiency
Status: COMPLETED
Conditions: Hepatic Insufficiency
Interventions: DRUG: Tipranavir (TPV)|DRUG: Ritonavir (r)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Intermittent Calorie Restriction on MASLD Patients With Abnormal Glucose Metabolism
Status: COMPLETED
Conditions: Fatty Liver Disease|Type 2 Diabetes|Impaired Glucose Regulation
Interventions: BEHAVIORAL: Intermittent calorie restriction (ICR)|BEHAVIORAL: Continuous calorie restriction (CCR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT