pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Hearing Preservation Using Dexamethasone and Hyaluronic Acid for Cochlear Implantation
Status: COMPLETED
Conditions: Hearing Loss
Interventions: DEVICE: Cochlear Implantation|DRUG: Cochlear Implantation+dexamethasone|DRUG: Cochlear Implantation+dexamethasone+hyaluronic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: BEETroot Juice to Reverse Functional Impairment in PAD
Status: RECRUITING
Conditions: Peripheral Artery Disease
Interventions: OTHER: Beetroot juice|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy With or Without Filgrastim in Treating Patients With Previously Untreated Extensive-Stage Small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer
Interventions: BIOLOGICAL: filgrastim|DRUG: carboplatin|DRUG: topotecan hydrochloride|RADIATION: WBRT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Do Discounted Vouchers for Medical Cannabis Reduce Opioid Use in Adults With Pain
Status: COMPLETED
Conditions: Opioid Use|Marijuana|Chronic Pain
Interventions: OTHER: Discounted Vouchers for Medical Cannabis Soft-Gel Capsule Products
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Treatment of Hepatocirrhosis and Portal Hypertension
Status: COMPLETED
Conditions: Hepatic Cirrhosis|Portal Hypertension
Interventions: PROCEDURE: Endoscopic therapy+ beta blockers|PROCEDURE: Endoscopic therapy+ PSE+beta blockers|PROCEDURE: beta blockers|PROCEDURE: Endoscopic therapy|PROCEDURE: Endoscopic therapy+ PSE|PROCEDURE: Somatostatin+Endoscopic therapy|PROCEDURE: Somatostatin+Endoscopic therapy+PSE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Psychometric Evaluation of Commonly Used Measures in Stroke
Status: UNKNOWN
Conditions: Stroke
Interventions: DIAGNOSTIC_TEST: The Computerized Adaptive Testing system of the Functional Assessment of Stroke|DIAGNOSTIC_TEST: The Barthel Index|DIAGNOSTIC_TEST: The National Institutes of Health Stroke Scale
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: First Live Birth Rate With eSET After Preimplantation Methylome Screening (PIMS) Versus Conventional In-vitro Fertilization
Status: RECRUITING
Conditions: Reproductive Techniques, Assisted|DNA Methylation
Interventions: OTHER: Using DNA methylome to select embryos|OTHER: Using morphologic score to select embryos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gemcitabine and Cisplatin for Gallbladder and Biliary Tract Cancer
Status: COMPLETED
Conditions: Gallbladder Cancer|Biliary Tract Cancer
Interventions: DRUG: Gemcitabine|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Feasibility of Performing Erector Spinae (ESP) Nerve Block in Bariatric Patients; a Case Series Study
Status: WITHDRAWN
Conditions: Nerve Pain
Interventions: PROCEDURE: Ultrasound Guided Erector Spinae Plane (ESP) Nerve Block|DRUG: Bupivacaine Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Between iLux and LipiFlow in the Treatment of Meibomian Gland Dysfunction (MGD): A 12-month, Multicenter Study
Status: COMPLETED
Conditions: Meibomian Gland Dysfunction|Evaporative Dry Eye Disease
Interventions: DEVICE: Systane iLux® Dry Eye System|DEVICE: LipiFlow® Thermal Pulsation System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Study on Effect and Neural Network Mechanism of Transcranial Direct Current Stimulation for Sudden Deafness With Tinnitus
Status: RECRUITING
Conditions: Tinnitus, Subjective|Sudden Deafness|Transcranial Direct Current Stimulation|Double-Blind Method|Female|Male|Human|Treatment Outcome
Interventions: DEVICE: Receive traditional medical therapy and transcranial direct current stimulation|DEVICE: Receive traditional medical therapy and sham stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: TACE Combined With Camrelizumab and Apatinib in the Treatment of Advanced Liver Cancer
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: camrelizumab& apatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Graft Material in Coronary Artery Bypass Grafting (CABG)
Status: COMPLETED
Conditions: Angina Pectoris
Interventions: PROCEDURE: Coronary artery bypass grafting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination of SBRT, PD-L1 Inhibitor, and Lenvatinib in Hepatocellular Carcinoma (HSBRT2401)
Status: RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: RADIATION: Stereotactic body radiotherapy|DRUG: Adebrelimab|DRUG: Lenvatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Investigating Tailored Treatment With Infliximab for Active Crohn's Disease
Status: COMPLETED
Conditions: Crohn's Disease
Interventions: DRUG: Infliximab|DRUG: Infliximab|DRUG: Infliximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: High Dose Versus Low Dose Oxytocin for Augmentation of Delayed Labour
Status: COMPLETED
Conditions: Birth; Delayed
Interventions: DRUG: Oxytocin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Corneal Endothelial Cell Density in Eyes Treated With a Fluocinolone Acetonide Intravitreal Implant
Status: COMPLETED
Conditions: Uveitis, Posterior
Interventions: DEVICE: Retisert|DRUG: Fluocinolone Acetonide Intravitreal Implant
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Red Wine, White Wine and Beer on Contrast-Medium Induced Acute Kidney Injury
Status: COMPLETED
Conditions: Chronic Renal Failure/ Kidney Disease|Contrast-medium Induced Acute Kidney Injury
Interventions: DIETARY_SUPPLEMENT: Red wine|DIETARY_SUPPLEMENT: White wine|DIETARY_SUPPLEMENT: Beer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of Safety, Tolerability, and Pharmacokinetics of Single Ascending Dosed of HSK31858 in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: HSK31858, tablet|DRUG: Placebo, tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Progesterone to Enhance the Efficacy and Success of Expectantly Managed Preterm Severe/Superimposed Preeclampsia
Status: RECRUITING
Conditions: Pregnancy
Interventions: DRUG: 17 OHPC
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: OTO-104 for Meniere's Disease
Status: COMPLETED
Conditions: Meniere's Disease
Interventions: DRUG: OTO-104 (steroid) 3 mg|DRUG: Placebo|DRUG: OTO-104 (steroid) 12 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nephropathy In Type 2 Diabetes and Cardio-renal Events
Status: COMPLETED
Conditions: Diabetic Nephropathy
Interventions: DRUG: SoC therapy|DRUG: irbesartan|DRUG: ramipril|DRUG: hydrochlorothiazide|DRUG: furosemide|DRUG: amlodipine|DRUG: atenolol|DRUG: doxazosin|DRUG: clonidine|DRUG: insulin|DRUG: simvastatin|DRUG: fibrate|DRUG: erythropoietin|DRUG: aspirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Phase I Study of Docetaxel and Temsirolimus in Resistant Solid Malignancies
Status: COMPLETED
Conditions: Resistant Solid Malignancies
Interventions: DRUG: Temsirolimus|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase III Clinical Trial to Evaluate the Efficacy and Safety of the Live Attenuated Varicella Vaccine
Status: ACTIVE_NOT_RECRUITING
Conditions: Varicella
Interventions: BIOLOGICAL: Investigational live attenuated varicella vaccine|BIOLOGICAL: Placebo of live attenuated varicella vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Patient Skin Dose in Interventional Radiology
Status: COMPLETED
Conditions: Aneurysm|Arteriovenous Malformations|Coronary Occlusion|Lung Neoplasms|Liver Neoplasms
Interventions: PROCEDURE: Interventional radiology : skin dose measurements
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Omitting Biopsy of SEntinel Lymph Node With Radiation After Neoadjuvant Chemotherapy in Breast Cancer (OBSERB) Trial
Status: NOT_YET_RECRUITING
Conditions: Breast Neoplasm Female|Lymphatic Metastasis
Interventions: PROCEDURE: Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Imaging Cardiac Amyloidosis: A Pilot Study Using F-18 Florbetapir Positron Emission Tomography
Status: TERMINATED
Conditions: Cardiac Amyloidosis
Interventions: DRUG: F-18 florbetapir PET
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Mindful SensoriMotor Therapy With Brain Modulation in Highly Impaired Extremities
Status: UNKNOWN
Conditions: Neuropathic Pain|Phantom Limb Pain
Interventions: DEVICE: Mindful SensoriMotor Therapy Enhanced with Brain Modulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vaginal Self-sampling for Detecting High-risk Human Papillomavirus Cervical Infection in Patients With Immune-mediated Inflammatory Diseases
Status: RECRUITING
Conditions: HPV Infection|Systemic Disease
Interventions: PROCEDURE: Vaginal self sampling detecting HPV
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Bryostatin 1 and Rituximab in Treating Patients With B-Cell Non-Hodgkin's Lymphoma or Chronic Lymphocytic Leukemia
Status: COMPLETED
Conditions: Leukemia|Lymphoma
Interventions: BIOLOGICAL: rituximab|DRUG: bryostatin 1
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Topical Ruxolitinib Evaluation in Vitiligo Study 1 (TRuE-V1)
Status: COMPLETED
Conditions: Non-segmental Vitiligo
Interventions: DRUG: Ruxolitinib cream|DRUG: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Exercise Training on Cognitive Performance and Sympathetic Activity in Obstructive Sleep Apnea
Status: UNKNOWN
Conditions: Obstructive Sleep Apnea
Interventions: OTHER: Exercise Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Gemcitabine/Cisplatin/Nab-Paclitaxel and Rilvegostomig in Resectable iCCA
Status: NOT_YET_RECRUITING
Conditions: Cholangiocarcinoma Resectable
Interventions: DRUG: Gemcitabine/Cisplatin/Nab-Paclitaxel and Rilvegostomig
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Lanadelumab (SHP643) in Chinese Participants With Hereditary Angioedema (HAE)
Status: COMPLETED
Conditions: Hereditary Angioedema (HAE)
Interventions: DRUG: Lanadelumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevalence of Temporomandibular Joint Dysfunction in Patients With Ankylosing Spondylitis
Status: COMPLETED
Conditions: Ankylosing Spondylitis
Interventions: DIAGNOSTIC_TEST: Diagnostic Criteria for Temporomandibular Disorders (DC/TMD) Axis I and II
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Post-marketing Safety Study of GlaxoSmithKline (GSK) Biologicals' Synflorix™ Vaccine, in Healthy Infants and Children in Sri Lanka
Status: WITHDRAWN
Conditions: Immunisation Against Streptococcus Pneumoniae
Interventions: OTHER: Synflorix™ data collection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of Silodosin and Pelvic Floor Muscle Training in Men With Benign Prostatic Hyperplasia and Overactive Bladder
Status: COMPLETED
Conditions: Benign Prostatic Hyperplasia (BPH)|Overactive Bladder
Interventions: BEHAVIORAL: Pelvic floor muscle training (PFMT) with suppressive urgency technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Learning Effects of Attentional Strategy on Dual-task Walking in Patients With Parkinson's Disease: Behavioral Performance and Neural Plasticity
Status: TERMINATED
Conditions: Parkinson Disease
Interventions: BEHAVIORAL: [year1] dual-task training with task priority strategy|BEHAVIORAL: [year2-3] dual-task training with internal and external focus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Diagnostic Potential of Artificial Intelligence-assisted Fecal Microbiome Testing for Colon Cancer
Status: RECRUITING
Conditions: Colon Cancer|Microbiota|Colonoscopy
Interventions: DIAGNOSTIC_TEST: Artificial Intelligence-assisted Fecal Microbiome Testing|PROCEDURE: Colonoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of Psyllium 6.8 g Versus Placebo on Satiety in Healthy Volunteers
Status: COMPLETED
Conditions: Hunger
Interventions: DIETARY_SUPPLEMENT: psyllium fiber 6.8g|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Phase I Single-dose Escalation Clinical Trial of Salvianolic Acid A Tablets
Status: UNKNOWN
Conditions: Neuropathy of Diabetes
Interventions: DRUG: Salvianolic Acid A|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Characteristics of Patients Diagnosed With NSAID Sensitivity in Thailand
Status: COMPLETED
Conditions: Aspirin Sensitivity|Aspirin-exacerbated Respiratory Disease|Aspirin-Induced Angioedema-Urticaria|Aspirin Allergy|NSAID-Induced Asthma|NSAID-Induced Angioedema-Urticaria|NSAID-Induced Anaphylactoid Reaction|Aspirin-Induced Anaphylactoid Reaction
Interventions: DRUG: aspirin, NSAIDs, paracetamol
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Zalutumumab Pharmacokinetics (PK) in Squamous Cell Carcinoma of the Head and Neck (SCCHN)
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: BIOLOGICAL: zalutumumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improving Functions in Veterans With Post-traumatic Peripheral Neuropathic Pain
Status: COMPLETED
Conditions: Neuropathic Pain
Interventions: DEVICE: Active Transcutaneous Magnetic Stimulation|DEVICE: Sham Transcutaneous Magnetic Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigate the Efficacy of Chemotherapy in Patients With Positive ctDNA After Surgery and Adjuvant Chemotherapy for a Stage III Colorectal Cancer
Status: NOT_YET_RECRUITING
Conditions: Colon or Upper Rectum Adenocarcinoma
Interventions: DRUG: "FOLFIRI" cures|DRUG: Trifluridine cures|BIOLOGICAL: BIOLOGICAL ASSESSMENT|OTHER: Questionnaires|OTHER: Thoracic-abdomino-pelvic scan or MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CO2 Laser vs Lidocaine for Vestibulodynia in Premenopausal Women
Status: COMPLETED
Conditions: Vulvodynia
Interventions: DEVICE: CO2 laser|DRUG: Lidocaine patch 5%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Using Mobile Devices for Neurofeedback to Reduce Opioid Use in Chronic Pain
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Pain|Opioid Use
Interventions: DEVICE: Mobile Neurofeedback App
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: A Bioequivalence Study of Pegylated Interferon Alfa-2a (PEG-IFN Alfa-2a) Benzyl Alcohol (BA)-Free Formulation Versus PEG-IFN Alfa-2a (Pegasys) Following Subcutaneous Administration
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: PEG-IFN alfa-2a BA-free formulation (Test)|DRUG: PEG-IFN alfa-2a market formulation (Reference)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Assess the Safety, Pharmacokinetics, and Preliminary Efficacy of ATG 016 Monotherapy in Patients With Advanced Solid Tumors
Status: TERMINATED
Conditions: Advanced Solid Tumors
Interventions: DRUG: ATG-016
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating the Safety and Efficacy of GLPG5101 (19CP02) in Participants With Non-Hodgkin Lymphoma
Status: RECRUITING
Conditions: Relapsed/Refractory B-cell Non-Hodgkin Lymphoma|Lymphomas Non-Hodgkin's B-cell
Interventions: GENETIC: GLPG5101
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Assessing the Drug Levels, Drug Effects, and Safety of BMS-986322 in Healthy Participants
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DRUG: BMS-986322|OTHER: BMS-986322 Placebo|DRUG: famotidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Beans to Enrich the Gut Microbiome vs. Obesity's Negative Effects (BE GONE) Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Colorectal Cancer Prevention
Interventions: OTHER: Regular Diet|OTHER: Navy Beans (Canned)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Small Subcutaneous Glucagon Dose to Treat Hypoglycemia in Adults With Type 1 Diabetes
Status: WITHDRAWN
Conditions: Type 1 Diabetes
Interventions: PROCEDURE: Hypoglycaemic hyperinsulinemic clamp|DRUG: Glucagon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Blood Flow Stimulation in the Lower Limbs by Application of Different External Devices
Status: COMPLETED
Conditions: Venous Stasis|Deep Vein Thrombosis
Interventions: DEVICE: Foot IPC|DEVICE: Rapid calf IPC|DEVICE: Slow calf IPC|DEVICE: Calf NMES
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Flavocoxid, A Plant-Derived Therapy, for the Treatment of Knee Osteoarthritis
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DRUG: Flavocoxid|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Optical Quality, Threshold Target Identification, and Military Target Task Performance After Advanced Keratorefractive Surgery
Status: COMPLETED
Conditions: Myopia|Myopic Astigmatism
Interventions: PROCEDURE: WFG PRK|PROCEDURE: WFG LASIK|PROCEDURE: WFO PRK|PROCEDURE: WFO LASIK
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sensory Testing of Multiple Forms of Spinal Cord Stimulation for Pain
Status: COMPLETED
Conditions: Chronic Pain|Failed Back Surgery Syndrome|Complex Regional Pain Syndromes|Neuropathic Pain
Interventions: DEVICE: Spinal cord stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lesinurad/Allopurinol 200/300 Fixed-Dose Combination (FDC) Tablets Bioequivalence.
Status: COMPLETED
Conditions: Gout
Interventions: DRUG: lesinurad/allopurinol 200/300 FDC tablets|DRUG: lesinurad 200 mg|DRUG: allopurinol 300 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study of MM-121 in Combination With Multiple Anticancer Therapies in Patients With Advanced Solid Tumors
Status: COMPLETED
Conditions: Solid Tumors
Interventions: DRUG: MM-121|DRUG: Carboplatin|DRUG: Pemetrexed|DRUG: Cabazitaxel|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single-Use Negative Pressure Wound Therapy for Free Flap Donor Sites
Status: COMPLETED
Conditions: Surgical Wound
Interventions: DEVICE: PICO Single Use Negative Pressure Wound Therapy System|DEVICE: xeroform gauze
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: National,Multicentric Randomised Study of the Correction of Genital Prolapse With Fascial Repair or Mesh-Prolift
Status: UNKNOWN
Conditions: Genital Prolapse
Interventions: PROCEDURE: fascial repair|PROCEDURE: mesh repair
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Value of Using Pioglitazone in Chronic Myeloid Leukemia Treatment
Status: COMPLETED
Conditions: Chronic Myelogenous Leukemia, BCR-ABL Positive|CML, Chronic Phase
Interventions: DRUG: Pioglitazone 15mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of Reduning Injection for the Treatment of Influenza in Children
Status: UNKNOWN
Conditions: Influenza in Children
Interventions: DRUG: Reduning injection|DRUG: Oseltamivir phosphate granules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dural Puncture Epidural Technique During Cesarean Section
Status: COMPLETED
Conditions: Anesthesia, Obstetric
Interventions: PROCEDURE: Dural Puncture Epidural technique using pencil-point 25G Whitacre needle|PROCEDURE: Dural Puncture Epidural technique using pencil-point 27G Whitacre needle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Failure Rate of GLyburide And Metformin Among Gestational Diabetics
Status: WITHDRAWN
Conditions: Gestational Diabetes Mellitus, Class A2
Interventions: DRUG: Glyburide|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Carbohydrate Counting and DASH Intervention Among Children With Diabetes and Celiac Disease.
Status: UNKNOWN
Conditions: Diabetes Mellitus, Type 1|Celiac Disease in Children
Interventions: BEHAVIORAL: diet therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Percutaneous Electrical Stimulation on Radial Nerve in Patients With Lateral Epicondylalgia
Status: WITHDRAWN
Conditions: Lateral Epicondylitis
Interventions: OTHER: PENS plus exercise|OTHER: Sham PENS plus exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vitamine D in Drug Resistant Epilepsy
Status: COMPLETED
Conditions: Drug Resistant Epilepsy
Interventions: DRUG: Cholecalciferol|DRUG: Placebo Oral
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Immunotherapy +/- EGFR Inhibitor In Advanced/Metastatic cSCC: Tackling Primary And Secondary Resistance
Status: UNKNOWN
Conditions: Skin Neoplasm
Interventions: DRUG: Pembrolizumab|DRUG: Cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Myocardial Characterization of Arrhythmogenic Mitral Valve Prolapse (STAMP: STretch and Myocardial Characterization in Arrhythmogenic Mitral Valve Prolapse)
Status: COMPLETED
Conditions: Mitral Valve Prolapse
Interventions: DEVICE: Cardiac MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: MK3207 for Treatment of Acute Migraines (3207-005)
Status: COMPLETED
Conditions: Migraine
Interventions: DRUG: MK3207- 2.5 mg|DRUG: MK3207- 5 mg|DRUG: MK3207- 10 mg|DRUG: MK3207- 20 mg|DRUG: MK3207- 50 mg|DRUG: MK3207- 100 mg|DRUG: Comparator: placebo (unspecified)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of a Nurse-led mHealth Program for Symptom Self-management of Breast Cancer Patients Undergoing Chemotherapy
Status: UNKNOWN
Conditions: Breast Cancer|Chemotherapeutic Toxicity
Interventions: DEVICE: mChemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Carpal Tunnel Syndrome - Randomized Clinical Trial Evaluating Effectiveness of Ultrasound in Corticosteroid Injection
Status: UNKNOWN
Conditions: Carpal Tunnel Syndrome
Interventions: DEVICE: Ultrasound|DRUG: methylprednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Omega-3 Fatty Acids on Risk Factors for Breast Cancer in Pre-menopausal Women
Status: COMPLETED
Conditions: Healthy|Premenopausal Period
Interventions: DIETARY_SUPPLEMENT: omega-3 fatty acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Physical Exercise for Education ('Fit to Study')
Status: COMPLETED
Conditions: Physical Activity|Mental Health Wellness 1|Cognitive Function 1, Social|Academic Attainment|Fitness Testing
Interventions: BEHAVIORAL: Physical Education (PE) Programme
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Influences of Balance Training With a Dynamometric Platform in Total Knee Arthroplasty
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: OTHER: Functional Recovery|OTHER: Balance Training|OTHER: Dynamometric Platform Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fibrinogen Concentrate In Children Cardiac Surgery 2
Status: UNKNOWN
Conditions: C.Surgical Procedure; Cardiac|Blood Coagulation Disorders|Hypofibrinogenemia
Interventions: DRUG: Fibrinogen Concentrate|OTHER: control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of Glaucoma Therapy to Treat Open-Angle Glaucoma or Ocular Hypertension
Status: COMPLETED
Conditions: Glaucoma|Ocular Hypertension
Interventions: DRUG: Travoprost 40 mcg/ml + Timolol 5 mg/ml eye drops, solution (DuoTrav)|DRUG: Dorzolamide 20 mg/ml + Timolol 5 mg/ml eye drops, solution (Cosopt)|OTHER: Timolol Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study Comparing Two Test Products With One Reference Product, All Containing 5 mg Yohimbine
Status: COMPLETED
Conditions: Erectile Dysfunction
Interventions: DRUG: Yohimbine|DRUG: Yohimbine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Experimental Pneumococcal Carriage in People Living With HIV
Status: NOT_YET_RECRUITING
Conditions: Pneumococcus; Pneumonia|Hiv
Interventions: OTHER: Streptococcus pneumoniae serotype 6B
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Non-invasive Intervention (BreEStim) for Management of Phantom Limb Pain (PLP) After Limb Amputation (Experiment 1)
Status: RECRUITING
Conditions: Pain Management
Interventions: DEVICE: BreEStim|DEVICE: EStim
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: RIC Allo-HSCT vs. Venetoclax-Based Consolidation in Elderly AML Patients After First CR
Status: RECRUITING
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Venetoclax|DRUG: Allogeneic transplant
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Changes in Biomarkers Using Prostaglandin Inhibitors
Status: COMPLETED
Conditions: Biomarker Change Linked to Breast Cancer
Interventions: DRUG: placebo/celecoxib 400 mg and cholecalciferol 400 IU/cholecalciferol 2,000 IU
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of Oral Minoxidil to Treat Hair Loss in Children, Teens, and Young Adults Who Are Cancer Survivors
Status: RECRUITING
Conditions: Survivors of Childhood Cancer|Alopecia
Interventions: DRUG: Oral Minoxidil|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Evaluate the Efficacy and Safety of Fesoterodine in Comparison to Tolterodine for Overactive Bladder (OAB)
Status: COMPLETED
Conditions: Overactive Bladder
Interventions: DRUG: fesoterodine fumarate|DRUG: placebo|DRUG: tolterodine tartrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Continuous Infusion Versus Intermittent Boluses of Cisatracurium in the Early Management of Pediatric ARDS
Status: UNKNOWN
Conditions: Respiratory Distress Syndrome, Pediatric|Acute Lung Injury/Acute Respiratory Distress Syndrome (ARDS)
Interventions: DRUG: Intermittent boluses of Cisatracurium|DRUG: Intravenous infusion of Cisatracurium for 24 hours
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Probiotics as a Prophylactic Aid in Women With Recurrent Urinary Tract Infections (UTI's)
Status: UNKNOWN
Conditions: Urinary Tract Infections
Interventions: DIETARY_SUPPLEMENT: UREX-cap-5|DIETARY_SUPPLEMENT: UREX-cap-5|DIETARY_SUPPLEMENT: Placebo Y cap G-3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Bendamustine and Idarubicin in Treating Older Patients With Previously Untreated AML or MDS
Status: COMPLETED
Conditions: Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities|Adult Acute Myeloid Leukemia With Del(5q)|Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)|Adult Acute Myeloid Leukemia With t(15;17)(q22;q12)|Adult Acute Myeloid Leukemia With t(16;16)(p13;q22)|Adult Acute Myeloid Leukemia With t(8;21)(q22;q22)|de Novo Myelodysplastic Syndromes|Myelodysplastic Syndrome With Isolated Del(5q)|Untreated Adult Acute Myeloid Leukemia
Interventions: DRUG: bendamustine hydrochloride|DRUG: idarubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intravitreal Ranibizumab For Persistent New Vessels In Diabetic Retinopathy(Inipe Study)
Status: UNKNOWN
Conditions: Proliferative Diabetic Retinopathy
Interventions: DRUG: Intravitreal injection of ranibizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Therapeutic Effect of Isogladine Maleate on Small Intestinal Mucosal Injury Associated With NSAIDS in Population
Status: UNKNOWN
Conditions: NSAIDs-associated Intestinal Mucosal Injury
Interventions: DRUG: Irsogladine Maleate|DRUG: Hydrotalcite
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Verify Effectiveness and Safety of Paclitaxel-Coated Coronary Balloon Catheters Swide®
Status: NOT_YET_RECRUITING
Conditions: Coronary Artery Disease
Interventions: DEVICE: Paclitaxel-Coated Coronary Balloon Catheters|DEVICE: Paclitaxel-Releasing Coronary Balloon Catheters
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cone Beam CT for Diagnosis of Select Otorhinolaryngology (ENT) Indications at Lower Dose
Status: COMPLETED
Conditions: CerebroSpinal Fluid (CSF) Leak|Chronic Otitis Media|Otospongiosis|Otosclerosis|Pulsatile Tinnitus|Cholesteatoma
Interventions: RADIATION: Radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Blended Gaming COVID-19 Training System (BGCTS) With WHO Guidelines for Staff in Residential Care Homes
Status: UNKNOWN
Conditions: Infection Control|COVID-19
Interventions: BEHAVIORAL: Blended Gaming COVID-19 Training System (BGCTS)|BEHAVIORAL: Usual care, infection control briefing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Breath Analysis in Obstructive Sleep Apnoea
Status: COMPLETED
Conditions: Obstructive Sleep Apnoea (OSA)
Interventions: DEVICE: Placebo-CPAP device|DEVICE: CPAP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Phase II Study of Capecitabine and Docetaxel in Previously Untreated Advanced Non-Small Cell Lung Cancer Patients
Status: COMPLETED
Conditions: Lung Cancer|Non-Small-Cell Lung Carcinoma
Interventions: DRUG: Capecitabine|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of OSA Associated Hypertension With Alpha 2 Agonist or Diuretic
Status: COMPLETED
Conditions: Obstructive Sleep Apnea
Interventions: DRUG: Guanfacine|DRUG: Hydrochlorothiazide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acrylamide and Health Outcomes
Status: RECRUITING
Conditions: Dementia|Dementia Alzheimers|Parkinson Disease|Myocardial Infarction
Interventions: OTHER: dietary acrylamide exposure measured via biomarkers in blood (hemoglobin adducts of acrylamide and glycidamide)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparing the Secondary Stability of Dental Implants: Immediate Gradual Loading Versus Early Loading Protocol in Posterior Maxilla
Status: UNKNOWN
Conditions: Dental Implant|Transmucosal Healing|Bone Loss
Interventions: PROCEDURE: immediate progressive loading using gingival formers|PROCEDURE: submerged healing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Acutherapy to Prevent Aromatase Inhibitor-Associated Arthralgias in Non-Hispanic Black Postmenopausal Women With Early-Stage Breast Cancer
Status: NOT_YET_RECRUITING
Conditions: Anatomic Stage I Breast Cancer AJCC v8|Anatomic Stage II Breast Cancer AJCC v8|Anatomic Stage III Breast Cancer AJCC v8|HER2-Negative Breast Carcinoma|Hormone Receptor-Positive Breast Carcinoma
Interventions: PROCEDURE: Acupressure Therapy|DEVICE: Acupuncture Therapy|DRUG: Aromatase Inhibition Therapy|OTHER: Discussion|OTHER: Survey Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: VIsceral Fat Reduction Assessed by CT-scan On RImonabAnt
Status: COMPLETED
Conditions: Metabolic Syndrome
Interventions: DRUG: Rimonabant|DRUG: Placebo (for Rimonabant)|OTHER: Mild hypocaloric diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Lucentis as an Adjuvant Therapy With TTT-ICG Based in Choroidal Melanoma
Status: COMPLETED
Conditions: Choroidal Melanoma
Interventions: DRUG: Ranibizumab injection and TTT - ICG based
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Imatinib Mesylate in Neurofibromatosis Type I Patients Aged 2 to 21 With Plexiform Neurofibromas
Status: TERMINATED
Conditions: Plexiform Neurofibromas
Interventions: DRUG: Imatinib Mesylate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I Safety and Feasibility Study of Intracoronary Delivery of Autologous Bone Marrow Derived Mononuclear Cells
Status: COMPLETED
Conditions: Congenital Heart Disease
Interventions: BIOLOGICAL: Autologous Bone Marrow-derived Mononuclear Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stem Cell Spinal Cord Injury Exoskeleton and Virtual Reality Treatment Study
Status: ENROLLING_BY_INVITATION
Conditions: Spinal Cord Injuries|Spinal Cord Compression|Spinal Cord Ischemia|Spinal Cord Diseases|Spinal Paralysis|Paraplegia|Paraplegia, Spinal|Paraplegia/Paraparesis|Paraplegia; Traumatic|SCI - Spinal Cord Injury
Interventions: PROCEDURE: Paraspinal|PROCEDURE: Paraspinal EX|PROCEDURE: Paraspinal VR
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study in Older Subject to Evaluate the Safety and Ability of Andexanet Alfa to Reverse the Anticoagulation Effect of Rivaroxaban
Status: COMPLETED
Conditions: Bleeding
Interventions: BIOLOGICAL: Andexanet|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: NADPH Oxidase Correction in mRNA-transfected Granulocyte-enriched Cells in Chronic Granulomatous Disease (CGD)
Status: RECRUITING
Conditions: Chronic Granulomatous Disease|Infection
Interventions: BIOLOGICAL: gp91 Grans
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intraperitoneal Analgesia After Laparoscopic Cholecystectomy
Status: COMPLETED
Conditions: Laparoscopic Cholecystectomy
Interventions: DRUG: lignocaine|DRUG: bupevacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Platinum-doublet Chemotherapy and Nivolumab for the Treatment of Subjects With Neuroendocrine Neoplasms (NENs) of the Gastroenteropancreatic (GEP) Tract or of Unknown (UK) Origin.
Status: ACTIVE_NOT_RECRUITING
Conditions: Neuroendocrine Tumors|Neuroendocrine Neoplasm|Gastroenteropancreatic Neuroendocrine Tumor
Interventions: DRUG: Nivolumab|DRUG: Carboplatin|DRUG: Etoposide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Radiofrecuency on Stretch Marks
Status: SUSPENDED
Conditions: Stretch Marks
Interventions: DEVICE: Fractitional Radiofrecuency with Drug Delivery|DEVICE: Fractitional Radiofrecuency
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: TMC435-TiDP16-C121: A Study Comparing 2 Tablet Formulations of TMC435 to an Established Capsule Formulation and Evaluating the Effect of Food on Blood Levels of TMC435
Status: COMPLETED
Conditions: Hepatitis C Virus
Interventions: DRUG: TMC435
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fentanyl vs. Low-Dose Ketamine for the Relief of Moderate to Severe Pain in Aeromedical Patients
Status: WITHDRAWN
Conditions: Trauma|Pain
Interventions: DRUG: Ketamine|DRUG: Fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Ketamine In Thoracic Surgery (KITS) Trial
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DRUG: Ketamine|DRUG: 0.9% saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 2B Active: Outpatient Rehabilitation for Adolescents With Chronic Pain
Status: COMPLETED
Conditions: Chronic Pain
Interventions: BEHAVIORAL: Multimodal Rehabilitation Program|BEHAVIORAL: Care as Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sit-to-stand Test in Cystic Fibrosis Children and Adolescents
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: BEHAVIORAL: Sit-to-stand test|BEHAVIORAL: 6-Minute Walk Test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: The Gut Microbiome and Immune Checkpoint Inhibitor Therapy in Solid Tumors
Status: RECRUITING
Conditions: Non-Small-Cell Lung Carcinoma|Malignant Melanoma|Renal Cell Carcinoma|Triple-Negative Breast Cancer
Interventions: DRUG: Checkpoint Inhibitor, Immune
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Neutrophil Gelatinase Associated Lipocalin and Kidney Injury Molecule-1 As Biomarkers of AKI in Children With DKA
Status: NOT_YET_RECRUITING
Conditions: Diabetes Mellitius
Interventions: DIAGNOSTIC_TEST: Neutrophil Gelatinase and Kidney Injury Molecule-1
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Combined Physical-cognitive Exercise and Dietary Intervention for Postmenopausal Obese Women
Status: COMPLETED
Conditions: Obesity
Interventions: BEHAVIORAL: Dietary intervention combined with physical-cognitive exergaming|BEHAVIORAL: Dietary intervention|BEHAVIORAL: Physical-cognitive intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Enteral Feeding of Premature Babies and Olive Oil Supplementation
Status: RECRUITING
Conditions: Premature|Olive Oil|Enteral Feeding
Interventions: DIETARY_SUPPLEMENT: Extra virgin organic olive oil (ULTRA PREMIUM)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of Transfers of Fresh and Thawed Embryos in Normal Responder Patients
Status: COMPLETED
Conditions: Infertility
Interventions: PROCEDURE: Embryo cryopreservation|PROCEDURE: Fresh blastocyst transfer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT