pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: EPLBD With Limited EST vs. EPLBD for Choledocholithiasis
Status: RECRUITING
Conditions: Choledocholithiasis
Interventions: PROCEDURE: EPLBD|PROCEDURE: ELPBD+ESD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety of Cat-PAD to Treat Cat Allergy in Cat Allergic Subjects With Controlled Asthma
Status: COMPLETED
Conditions: Cat Allergy
Interventions: BIOLOGICAL: Cat-PAD|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: REFOCUS: A First-in-Human Study of Highly Selective FGFR2 Inhibitor, RLY-4008, in Patients With ICC and Other Advanced Solid Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: FGFR2 Amplification|FGFR2 Gene Mutation|FGFR2 Gene Fusion/Rearrangement|FGFR2 Gene Translocation|FGFR2 Gene Activation|Intrahepatic Cholangiocarcinoma|Cholangiocarcinoma|Other Solid Tumors, Adult
Interventions: DRUG: RLY-4008
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of BHV-3241 in Participants With Multiple System Atrophy
Status: COMPLETED
Conditions: Multiple System Atrophy
Interventions: DRUG: Verdiperstat|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Red and Processed Meat Effects on the Metabolome and Microbiome
Status: COMPLETED
Conditions: Controlled Feeding Trial|Healthy Eating Index|Red Meat|Meat
Interventions: OTHER: Randomized, cross-over controlled feeding trial testing a Healthy Eating Index 2015 (HEI-2015) diet with and without red and processed meat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Comparing Tunlametinib Capsules and Combination Chemotherapy in Advanced NRAS-mutant Melanoma
Status: RECRUITING
Conditions: Melanoma
Interventions: DRUG: tunlametinib|DRUG: paclitaxel +carboplatin, or temozolomide +cisplatin, or dacarbazine +cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Effects of Cytochrome P450 1A2 Induction by Ritonavir on BMS-986165 Drug Levels and Effects in Healthy Participants
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DRUG: BMS-986165|DRUG: Ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Treatment of Obesity With Topiramate in Patients With Polycystic Ovary Syndrome
Status: UNKNOWN
Conditions: Obesity|Polycystic Ovary Syndrome|Hyperandrogenism
Interventions: DRUG: Topiramate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of a Plasmid HIV Vaccine in HIV Uninfected Adults
Status: COMPLETED
Conditions: HIV Infection
Interventions: BIOLOGICAL: ADVAX
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Trial to Compare the Duration of Analgesic Efficacy and Safety of Naproxen Sodium Tablets and Ibuprofen Tablets in Postsurgical Dental Pain
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: DRUG: Naproxen Sodium (Aleve, BAY117031)|DRUG: Ibuprofen (Advil)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Association Between Bolus Rate and the Adequacy of Labor Analgesia Using Timed-intermittent Boluses
Status: COMPLETED
Conditions: Labor Pain|Obstetric Pain
Interventions: DEVICE: CADD-Solis pump (Smiths Medical)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Pantoprazole in Patients Older Than 18 Years Who Have Symptoms of Acid Reflux (Gastroesophageal Reflux Disease) (BY1023/M3-339)
Status: COMPLETED
Conditions: Gastroesophageal Reflux
Interventions: DRUG: Pantoprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tenodesis vs. Self-locking Tenotomy in Long Head of the Biceps Tendon Lesions: A Randomized Clinical Trial
Status: TERMINATED
Conditions: Tenodesis|Tenotomy
Interventions: PROCEDURE: Biceps Tenodesis|PROCEDURE: Self-locking "T" Tenotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of TK3 in Improving Quality of Life in Patients With Malignancy Under Chemotherapy
Status: UNKNOWN
Conditions: Cancer
Interventions: DIETARY_SUPPLEMENT: TK3|DIETARY_SUPPLEMENT: 1 capsule, 3 times per day
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: DP13 - A Phase II Study in Patients With Primary Aldosteronism
Status: COMPLETED
Conditions: Primary Aldosteronism
Interventions: DRUG: DP13
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Therapy With Camostat Mesilate + Hydroxychloroquine for COVID-19
Status: WITHDRAWN
Conditions: COVID
Interventions: DRUG: Camostat Mesilate|DRUG: Placebo|DRUG: Hydroxychloroquine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rituximab and Cyclophosphamide in Treating Patients With High Risk, Refractory, or Relapsed Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma and Plasma Cell Neoplasm
Interventions: BIOLOGICAL: rituximab|DRUG: cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HPV Self-Sampling in Somali Women
Status: ACTIVE_NOT_RECRUITING
Conditions: Cervical Cancer|Papillomavirus Infection|Uterine Diseases|Uterine Cervical Disease
Interventions: DEVICE: COPAN 552c.80 FLOQSwab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Bioequivalence Study of Bicalutamide 50 mg Tablet and Casodex® 50 mg Tablet in Healthy Subjects Under Fed Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Bicalutamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Efficacy and Safety of LY06006 in Postmenopausal Women With Osteoporosis at High Risk for Fracture
Status: UNKNOWN
Conditions: Postmenopausal Osteoporosis
Interventions: DRUG: LY06006
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Effectiveness of Treatment of Sarcopenia With the Use of a Medicinal Product (Nandrolone), Comprehensive Physiotherapy and Diet
Status: RECRUITING
Conditions: Sarcopenia
Interventions: DRUG: Nandrolone Decanoate|BEHAVIORAL: Physiotherapy Intervention|BEHAVIORAL: Nutritional Intervention|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Continuous Adductor Canal Block in Outpatient Total Knee Arthroplasty
Status: RECRUITING
Conditions: Knee Arthroplasty, Total|Anesthesia, Regional|Acute Pain
Interventions: DRUG: Continuous adductor canal block (CACB)|DRUG: Sham continuous adductor canal block (ShACB).
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Near-infrared Spectroscopy Neurofeedback as a Treatment for Children With Attention Deficit Hyperactivity Disorder
Status: UNKNOWN
Conditions: Neurofeedback|Attention Deficit Hyperactivity Disorder (ADHD)
Interventions: BEHAVIORAL: NIRS neurofeedback|DRUG: Methylphenidate or Tomoxetine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SHR-A1904 Combinations in CLDN18.2-Positive Advanced Solid Tumor
Status: RECRUITING
Conditions: Cldn18.2-positive Advanced Solid Tumor
Interventions: DRUG: SHR-A1904; Adebrelimab|DRUG: SHR-A1904; CAPOX; Adebrelimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Robotic vs. Laparoscopic vs. Open Living Donor Hepatectomy
Status: ENROLLING_BY_INVITATION
Conditions: End Stage Liver Disease|Acute Liver Failure|Acute-On-Chronic Liver Failure|Hepatocellular Carcinoma
Interventions: PROCEDURE: Donor hepatectomy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Disitamab Vedotin Combined With BCG Therapy in HER2-expressing High-risk Non-muscle Invasive Bladder Cancer
Status: RECRUITING
Conditions: Non-muscle Invasive Bladder Cancer|HER-2 Protein Overexpression
Interventions: DRUG: Disitamab vedotin|DRUG: Bacillus Calmette Guerin Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effect of Fluconazole and Itraconazole on Erdafitinib Pharmacokinetics in Healthy Adult Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Erdafitinib|DRUG: Fluconazole|DRUG: Itraconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Dementia Family Caregiver Study
Status: RECRUITING
Conditions: Dementia Caregiver
Interventions: BEHAVIORAL: Community Health Worker (CHW) Home Visit Intervention|BEHAVIORAL: Attention Control Group with WIoT Technology|BEHAVIORAL: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy of Philips Sonicare Flexcare Platinum Toothbrush® Compared to Manual Brushing in Healthy Patients: a 1 Year Follow up
Status: COMPLETED
Conditions: Gingivitis
Interventions: DEVICE: Sonic Toothbrush|DEVICE: Manual Toothbrush
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Minimal Clinically Significant Difference (MCID) of Multidimensional Dyspnea Profile (MDP) in COPD Patients Undergoing Respiratory Rehabilitation
Status: NOT_YET_RECRUITING
Conditions: COPD
Interventions: OTHER: constant work-rate cycling exercise test
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pilot Study for the Evaluation of Intravitreal Infliximab in the Treatment of Uveitic Macular Edema
Status: WITHDRAWN
Conditions: Uveitic Macular Edema|Intraocular Inflammation
Interventions: DRUG: Infliximab (intravitreal, 2.0mg/0.05ml)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of MM-398 With or Without 5-FU/LV, Versus 5-FU/LV in Patients With Metastatic Pancreatic Cancer
Status: COMPLETED
Conditions: Metastatic Pancreatic Cancer
Interventions: DRUG: MM-398|DRUG: 5 Fluorouracil|DRUG: Leucovorin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intra-articular Analgesia Versus Adductor Canal Block for Arthroscopic Knee Surgery
Status: UNKNOWN
Conditions: Post-Operative Pain, Chronic
Interventions: DRUG: Adductor Canal Block|DRUG: Intra-articular Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, Pharmacokinetic Characteristics, and Preliminary Efficacy Evaluation of GST-HG161
Status: UNKNOWN
Conditions: Solid Tumor|C-Met Mutation-Related Tumors
Interventions: DRUG: GST-HG161
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 0.3% Sodium Hyaluronate in the Treatment of Dry Eye of Diabetic Patients
Status: UNKNOWN
Conditions: Dry Eye Syndromes|Diabetes Mellitus
Interventions: DRUG: 0.3% Sodium Hyaluronate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Dexmedetomidine for Sedation During Flexible Bronchoscopy in Patients With COPD: A Descriptive Study
Status: COMPLETED
Conditions: Sedation|Flexible Bronchoscopy|COPD
Interventions: DRUG: dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multicenter Trial of Abiraterone Acetate With or Without Cabazitaxel in Treatment of Metastatic Castration Resistant Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: Abiraterone acetate 1000 mg po daily|DRUG: Cabazitaxel 25 mg/m2 IV|DRUG: prednisone 5 mg po BID
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Plinabulin vs. Pegfilgrastim in Patients With Solid Tumors Receiving Docetaxel Myelosuppressive Chemotherapy Phase 3
Status: COMPLETED
Conditions: Chemotherapy-induced Neutropenia
Interventions: DRUG: Plinabulin|DRUG: Pegfilgrastim|OTHER: Saline Placebo|OTHER: D5W Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Combination of Ibuprofen With Curcumin Covered With Liquorice Root Supplementation in the Management of Postoperative Dental Pain in Adults
Status: NOT_YET_RECRUITING
Conditions: Dental Pain
Interventions: DIETARY_SUPPLEMENT: ibuprofen 400 mg in combination with Curcumin covered with liquorice root 100 mg|DIETARY_SUPPLEMENT: ibuprofen 200 mg in combination with Curcumin covered with liquorice root 100 mg|OTHER: The combination of ibuprofen 400 mg and placebo in patients after 2-4 molars procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Analgosedative adjuncT keTAmine Infusion iN Mechanically vENTilated ICU Patients
Status: COMPLETED
Conditions: Critical Illness|Sedation|Mechanical Ventilation
Interventions: DRUG: Ketamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I/II Trial of VELCADE & Gemcitabine for Patients With Relapsed or Refractory Aggressive B- and T-cell Non-Hodgkin's Lymphoma
Status: TERMINATED
Conditions: Lymphoma
Interventions: DRUG: bortezomib|DRUG: gemcitabine hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Azacitidine, Venetoclax, and Trametinib for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia or Higher-Risk Myelodysplastic Syndrome
Status: COMPLETED
Conditions: Recurrent Acute Myeloid Leukemia|Recurrent Chronic Myelomonocytic Leukemia|Recurrent Myelodysplastic Syndrome|Refractory Acute Myeloid Leukemia|Refractory Chronic Myelomonocytic Leukemia|Refractory Myelodysplastic Syndrome
Interventions: DRUG: Azacitidine|DRUG: Trametinib|DRUG: Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Glucomannan for the Treatment of Abdominal Pain-related Functional Gastrointestinal Disorders in Childhood
Status: COMPLETED
Conditions: Functional Gastrointestinal Disorders
Interventions: DRUG: Glucomannan|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Research on Diagnosis and Prognosis of Myocardial Ischemia Level Using Magnetocardiography
Status: NOT_YET_RECRUITING
Conditions: Stable Ischemic Heart Disease; Acute Coronary Syndrome; Myocardial Infarction; Myocardial Ischemia
Interventions: DEVICE: Magnetocardiography
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Intervention With Riboflavin to Improve Vascular Health and ENdothelial Functioning in Genetically at- Risk Adults
Status: UNKNOWN
Conditions: Blood Pressure|Hypertension
Interventions: DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: Riboflavin 1.6mg/d|DIETARY_SUPPLEMENT: Riboflavin 5mg/d|DIETARY_SUPPLEMENT: Riboflavin 20mg/d
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Efficacy, Safety and Pharmacokinetics of Three-times Weekly Dosing of GSK1278863 in Hemodialysis-dependent Subjects With Anemia Associated With Chronic Kidney Disease Who Are Switched From a Stable Dose of an Erythropoiesis-stimulating Agent
Status: COMPLETED
Conditions: Anaemia
Interventions: DRUG: GSK1278863|DRUG: GSK1278863 matching Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Personal Health Libraries for Formerly Incarcerated Individuals
Status: NOT_YET_RECRUITING
Conditions: Personal Health Information|Incarcerated Individuals
Interventions: DEVICE: Personal Health Library (PerHL) + MyChart|DEVICE: Epic®MyChart
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Neural Facilitation of Movements in People With SCI
Status: TERMINATED
Conditions: Spinal Cord Injuries
Interventions: OTHER: Electrophysiology assessment - corticospinal tract|OTHER: Electrophysiology assessment - reticulospinal tract|OTHER: Training with some stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Platelet Rich Plasma (PRP) on the Esthetic Outcome and Scar Formation of Unilateral Cleft Lip Repair
Status: TERMINATED
Conditions: Unilateral Cleft Lip
Interventions: BIOLOGICAL: platelet rich plasma
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Multi-center Study to Evaluate the Safety and Efficacy of PEP005 (Ingenol Mebutate) Gel, When Used to Treat Actinic Keratoses on Non-head Locations (Trunk and Extremities)
Status: COMPLETED
Conditions: Actinic Keratosis
Interventions: DRUG: PEP005 Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: AK117 (Anti-CD47) + Anti-EGFR for R/M HNSCC
Status: NOT_YET_RECRUITING
Conditions: Head and Neck Squamous Cell Carcinoma
Interventions: DRUG: AK117|DRUG: anti-EGFR
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improving College Students' Mental Help-Seeking Intention During the COVID-19 Pandemic
Status: COMPLETED
Conditions: Help-Seeking Behavior|Mental Health Issue
Interventions: BEHAVIORAL: Mental help-seeking self-persuasion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Comparison of Stryker's Tritanium Posterior Lumbar Cage and PEEK Implant
Status: TERMINATED
Conditions: Degenerative Disc Disease|Degenerative Scoliosis
Interventions: DEVICE: Tritanium Posterior Lumbar Cage|DEVICE: AVS UniLIF PEEK Posterior Lumbar Cage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of Herceptin (Trastuzumab) in Combination Chemotherapy in Women With Locally Advanced Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Trastuzumab|DRUG: Doxorubicin|DRUG: Paclitaxel|DRUG: CMF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of SLC19A3 Inhibition on the Pharmacokinetics of Thiamine
Status: COMPLETED
Conditions: Vitamin B1 Deficiency|Thiamine Deficiency
Interventions: DRUG: Trimethoprim|DRUG: Metformin|DIETARY_SUPPLEMENT: Vitamin B1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Clinical Performance of Bioactive Restorative Material Versus Glass Hybrid Restorative in Posterior Restorations
Status: UNKNOWN
Conditions: Dental Restoration Failure
Interventions: OTHER: Resin-modified glass ionomer|OTHER: Bulk-fill glass hybrid restorative
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Suvorexant (MK-4305) for the Treatment of Insomnia in Participants With Alzheimer's Disease (MK-4305-061)
Status: COMPLETED
Conditions: Sleep Initiation and Maintenance Disorders|Alzheimer Disease
Interventions: DRUG: Suvorexant|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Passive Static Stretching and Proprioceptive Neuromuscular Facilitation in Musculoskeletal Aspects
Status: COMPLETED
Conditions: Flexibility|Range of Motion
Interventions: OTHER: Muscle Stretching Exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety, Tolerability, and Effect of Alirocumab in High Cardiovascular Risk Patients With Severe Hypercholesterolemia Not Adequately Controlled With Conventional Lipid-modifying Therapies (ODYSSEY APPRISE)
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DRUG: ALIROCUMAB SAR236553 (REGN727)|DRUG: placebo (for injection training only)|DRUG: ezetimibe|DRUG: atorvastatin|DRUG: rosuvastatin|DRUG: simvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of an Intervention in Improving Medication Adherence Among Malay Patients With Underlying Type 2 Diabetes Mellitus in Malaysia
Status: COMPLETED
Conditions: Medication Adherence|Type 2 Diabetes Mellitus
Interventions: BEHAVIORAL: Know Your Medicine - Take It For Health (KYM-TIFH)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: First-in-Man Trial of NNC114-0005 in Healthy Subjects and Subjects With Rheumatoid Arthritis
Status: COMPLETED
Conditions: Inflammation|Rheumatoid Arthritis|Healthy
Interventions: DRUG: NNC0114-0000-0005|DRUG: NNC0114-0000-0005|DRUG: NNC0114-0000-0005|DRUG: NNC0114-0000-0005|DRUG: NNC0114-0000-0005|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1b Study of Imvotamab in Moderate to Severe Rheumatoid Arthritis
Status: RECRUITING
Conditions: Rheumatoid Arthritis|Arthritis, Rheumatoid|Arthritis
Interventions: DRUG: Imvotamab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Online WIC Nutrition Education to Promote Farmers' Market Fruit and Vegetable Purchases and Consumption
Status: COMPLETED
Conditions: Cardiovascular Diseases|Cancer|Type 2 Diabetes|Obesity
Interventions: BEHAVIORAL: WIC Fresh Start Program|BEHAVIORAL: Existing Online Health Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparative Effectiveness Study of Bubble CPAP Devices in the NICU
Status: COMPLETED
Conditions: Respiratory Distress Syndrome
Interventions: DEVICE: Bubble CPAP- BabiPlus, Respiralogics|DEVICE: Bubble CPAP- B&B Bubbler, B&B Medical devices
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Effect of Rabeprazole 50 mg DDR Capsules and 20 mg Enteric-coated Tablets
Status: COMPLETED
Conditions: Gastroesophageal Reflux Disease
Interventions: DRUG: Rabelis DDR 50 mg Capsules|DRUG: Pariet 20 mg Enteric Coated Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study to Evaluate the Safety and Efficacy of TQB2450 Injection in Relapsed or Refractory Classical Hodgkin's Lymphoma
Status: UNKNOWN
Conditions: Safety and Effectiveness
Interventions: DRUG: TQB2450
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PROPHY-VAP: Prevention of Early Ventilation Acquired Pneumonia (VAP) in Brain Injured Patients by a Single Dose of Ceftriaxone
Status: COMPLETED
Conditions: Early Ventilation Acquired Pneumonia in Brain Injured Patients
Interventions: DRUG: Anti-Infective Agents|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Impact of High-dose Pretreatment of Rosuvastatin in Patients With Acute Coronary Syndrome Following Off-pump Coronary Artery Bypass: Results From the HIROP-ACS (HIgh-dose Pretreatment of Rosuvastatin During Off-Pump Coronary Bypass in Acute Coronary Syndrome) Study
Status: COMPLETED
Conditions: A Total of 234 Patients With Acute Coronary Syndrome Who Will Undergo OPCAB.
Interventions: DRUG: Rosuvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: An Internet Cognitive-Behavioral Intervention for Youth With Type 1 Diabetes - Participation and Efficacy
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: BEHAVIORAL: An Internet Cognitive-Behavioral Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Percutaneous Radiofrequency Thermal Ablation in Compressive Thyroid Nodules
Status: COMPLETED
Conditions: Thyroid Nodule
Interventions: PROCEDURE: Percutaneous Radiofrequency Thermal Ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Personalized Objects Can Improve the Diagnosis of EMCS From MCS
Status: COMPLETED
Conditions: Patients in Minimally Conscious State
Interventions: BEHAVIORAL: Personalized Objects|BEHAVIORAL: non-personalized Objects
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Effects of Sitaglpitin on Endothelial Function During the OGTT in T2DM
Status: UNKNOWN
Conditions: Type 2 Diabetes
Interventions: OTHER: dieting|DRUG: Sitagliptin|DRUG: Glimepiride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Impact of a Novel Cannabinoid Product for Endometriosis
Status: NOT_YET_RECRUITING
Conditions: Endometriosis
Interventions: DRUG: Cannabidiol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: The Acute Effect of Proprioceptive Neuromuscular Facilitation on Cervical Range of Motion, Strength and Proprioception.
Status: COMPLETED
Conditions: Proprioception|Neck
Interventions: OTHER: Proprioceptive Neuromuscular Facilitation Patterns|OTHER: Proprioceptive Neuromuscular Facilitation stretching|OTHER: Passive range of motion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Oral AHR Antagonist in Combination With Nivolumab in Patients With PD-1 Resistant Metastatic or Recurrent Head and Neck Cancer
Status: WITHDRAWN
Conditions: Head and Neck Squamous Cell Carcinoma|Head and Neck Cancer|Head Cancer|Neck Cancer|Head Cancer Neck|Neck Carcinoma
Interventions: DRUG: IK-175 + nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Prospective, Randomized, Open, Parallel-controlled, Superior-efficacy Clinical Study of Radical Sigmoidectomy for Sigmoid Cancer Versus Radical Sigmoidectomy Combined With Indocyanine Green Fluorescence Imaging Lymphatic Tracing Dissection in the Treatment of Sigmoid Cancer
Status: NOT_YET_RECRUITING
Conditions: Sigmoid Cancer
Interventions: PROCEDURE: indocyanine green fluorescence imaging lymphatic tracing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Community-Onset Bacteremia Due to ESBL Producing E.Coli or K.Pneumoniae in China: Prevalence, Risk Factors and Prognosis
Status: COMPLETED
Conditions: Community Acquired Infection
Interventions: OTHER: bacteremia caused by ESBL producing E.coli or K.pneumoniae
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of a Mixture of New Probiotic Strains in Preterm Infants
Status: COMPLETED
Conditions: Premature Infant
Interventions: DIETARY_SUPPLEMENT: Lactobacillus PS11603 & Bifidobacterium PS10402|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Screening and Treatment of Obstructive Sleep Apnea in High-risk Pregnancy
Status: COMPLETED
Conditions: Sleep Apnea, Obstructive|Pre-Eclampsia|Hypertension, Pregnancy-Induced
Interventions: DEVICE: Continuous positive airway pressure (CPAP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Menstrual Cycle on Injection Pain of Rocuronium
Status: COMPLETED
Conditions: Pain, Menstrual
Interventions: DRUG: Rocuronium 0,6mg/kg|DRUG: Rocuronium 0,6mg/kg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Neoadjuvant Treatment of Locally-advanced Breast Cancer Patients With Ribociclib and Letrozole
Status: COMPLETED
Conditions: Breast Cancer|HER2-negative Breast Cancer|ER-positive Breast Cancer|Locally Advanced Breast Cancer|Luminal A Breast Cancer|Luminal B Breast Cancer
Interventions: DRUG: Letrozole 2.5mg oral tablet; Ribociclib 600mg oral tablet|DRUG: Goserelin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Resistive Inspiratory Muscle Training Optimizing Lung Function in Spinal Cord Injury
Status: NOT_YET_RECRUITING
Conditions: Spinal Cord Injury (SCI), Respiratory Complication
Interventions: OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Reduction of Human Papillomavirus (HPV) Viral Infectivity and Transmission in HPV-Positive Women After Vaccination With 9vHPV (RIFT-HPV)
Status: RECRUITING
Conditions: Cervical Intraepithelial Neoplasia Grade I/ II/ III (CIN I/II/III)|Human Papillomavirus (HPV) Infections|High-risk HPV|HPV-16/ 18
Interventions: BIOLOGICAL: Nonavalent HPV vaccine (9vHPV/Gardasil-9™).
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of Vanucizumab (RO5520985) Alone or in Combination With Atezolizumab in Participants With Locally Advanced or Metastatic Solid Tumors
Status: COMPLETED
Conditions: Neoplasms
Interventions: BIOLOGICAL: Atezolizumab [TECENTRIQ]|BIOLOGICAL: Vanucizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Treatment Efficacy With HD/MD Flu Plus Sal in Chronic Obstructive Pulmonary Disease (COPD) Patients
Status: UNKNOWN
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: fluticasone/ salmeterol 125/25 mcg/puff|DRUG: fluticasone/ salmeterol 250/25 mcg/puff
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Priming in Repetitive Transcranial Magnetic Stimulation in the Treatment of Obsessive Compulsive Disorder
Status: RECRUITING
Conditions: Obsessive-Compulsive Disorder
Interventions: DEVICE: Active Priming|DEVICE: Sham Priming
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An Open-label, Clinical Feasibility Study of the Efficacy of Remdesivir for Long-COVID.
Status: NOT_YET_RECRUITING
Conditions: SARS-CoV-2 Infection|COVID-19
Interventions: DRUG: Remdesivir
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Assessment of Fatigue in Psoriatic Arthritis and Cutaneous Psoriasis Patients
Status: RECRUITING
Conditions: Psoriatic Arthritis|Psoriasis
Interventions: BEHAVIORAL: Fatigue assessment|BEHAVIORAL: Quality of life assessment|OTHER: Assess severity of psoriatic arthritis|OTHER: Assess severity of cutaneous psoriasis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study of CD20/CD22 Targeted CAR T-cell Therapy for Relapsed or Refractory Lymphoid Malignancies
Status: RECRUITING
Conditions: Relapsed and Refractory|Lymphoid Hematological Malignancies
Interventions: DRUG: CD20/CD22 dual Targeted CAR T-cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CD19-CART(Relma-cel) for Moderate to Severe Active Systemic Lupus Erythematosus
Status: RECRUITING
Conditions: Systemic Lupus Erythematosus
Interventions: BIOLOGICAL: Relma-cel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antibiotic Prophylaxis and Renal Damage In Congenital Abnormalities of the Kidney and Urinary Tract
Status: ACTIVE_NOT_RECRUITING
Conditions: Vesicoureteral Reflux|Renal Hypodysplasia, Nonsyndromic, 1|Chronic Kidney Disease
Interventions: DRUG: nitrofurantoin|OTHER: No prophylaxis|DRUG: Amoxicillin-Potassium Clavulanate Combination|DRUG: Trimethoprim/sulfamethoxazole|DRUG: Cefixime
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Robust Evaluation to Measure Improvements in Nonadherence From Low-cost Devices
Status: COMPLETED
Conditions: Cardiovascular Disease|Diabetes|Breast Cancer|Depression|Mental Health Disorder|Prostatic Hypertrophy, Benign|Parkinson's Disease|Epilepsy
Interventions: BEHAVIORAL: RxTimerCap|BEHAVIORAL: Take-N-Slide|BEHAVIORAL: Pillbox
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Dual JAK1/TYK2 Inhibitor for Cicatricial Alopecia
Status: COMPLETED
Conditions: Cicatricial Alopecia
Interventions: DRUG: PF-06700841|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: L-carnitine to Treat Fatigue Associated With Crohn's Disease
Status: WITHDRAWN
Conditions: Crohn's Disease|Fatigue
Interventions: DRUG: L-carnitine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Automatic Oxygen Titration With O2matic® to Patients Admitted With COVID-19 and Hypoxemic Respiratory Failure
Status: COMPLETED
Conditions: Covid19|Hypoxemic Respiratory Failure|Hypoxemia
Interventions: DEVICE: Closed-loop control of oxygen supplementation by O2matic
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Breath-Hold Technique for Pancreatic Stereotactic Body Radiation Therapy (SBRT) Patients
Status: TERMINATED
Conditions: Pancreas Cancer
Interventions: BEHAVIORAL: Biofeedback|BEHAVIORAL: Active Breathing Control Technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: c9,t11-CLA in Children and Adolescents With Allergic Asthma
Status: COMPLETED
Conditions: Allergic Bronchial Asthma
Interventions: DIETARY_SUPPLEMENT: conjugated linoleic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sub-retinal Transplantation of hESC Derived RPE(MA09-hRPE)Cells in Patients With Stargardt's Macular Dystrophy
Status: COMPLETED
Conditions: Stargardt's Macular Dystrophy
Interventions: BIOLOGICAL: MA09-hRPE
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Phase 3 Trial for AML Patients in CR2 Comparing 8Gy TBI /Fludarabine to Conditioning With TBI 12Gy/Cyclophosphamide
Status: TERMINATED
Conditions: Acute Myeloid Leukemia
Interventions: PROCEDURE: conditioning for allogeneic HSCT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Camrelizumab Combined With Radiotherapy and Chemotherapy for the Treatment of Recurrent or Metastatic Cervical Cancer
Status: RECRUITING
Conditions: Locally Advanced Cervical Cancer
Interventions: BIOLOGICAL: Camrelizumab|RADIATION: radiotherapy|DRUG: Albumin Paclitaxel|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Regenerative Endodontics Using Different Intracanal Medicaments on Radiographic Outcomes and Periapical MMP-8 Levels
Status: COMPLETED
Conditions: Regenerative Endodontics
Interventions: COMBINATION_PRODUCT: Place the freshly prepared calcium hydroxide in to the root canals|COMBINATION_PRODUCT: Place the freshly prepared double antibiotic paste in to the root canals|DIAGNOSTIC_TEST: Taking standart periapical radiography with film holder|OTHER: Sample collection for immunofluorometric assay
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Iguratimod in Systemic Sclerosis
Status: UNKNOWN
Conditions: Systemic Sclerosis, Diffuse
Interventions: DRUG: Iguratimod|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bespoke vs Standard Instrumentation in TKR
Status: UNKNOWN
Conditions: Knee Osteoarthritis
Interventions: PROCEDURE: Patient specific cutting blocks|PROCEDURE: Conventional cutting blocks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Phase II Combination Stem Cell Therapy for the Treatment of Severe Leg Ischemia
Status: COMPLETED
Conditions: Critical Limb Ischemia|Severe Leg Ischemia|Peripheral Artery Disease|Peripheral Vascular Disease
Interventions: BIOLOGICAL: MESENDO|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Artificial Intelligence/Computer Guided Ridge Splitting for Treating Horizontal Ridge Defects
Status: RECRUITING
Conditions: Alveolar Bone Resorption|Dental Implant Failure Nos
Interventions: PROCEDURE: free-hand ridge splitting|PROCEDURE: AI/guided ridge splitting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Gefitinib Plus Combination Chemotherapy in Treating Patients With Locally Advanced or Metastatic Bladder Cancer
Status: COMPLETED
Conditions: Metastatic Transitional Cell Cancer of the Renal Pelvis and Ureter|Recurrent Transitional Cell Cancer of the Renal Pelvis and Ureter
Interventions: DRUG: gemcitabine hydrochloride|DRUG: cisplatin|DRUG: gefitinib|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigating the Acute Effects of THC on Functional Brain Systems
Status: COMPLETED
Conditions: Reward|Tetrahydrocannabinol|Endocannabinoids|Memory|Magnetic Resonance Imaging
Interventions: DRUG: Delta9-tetrahydrocannabinol (THC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Allogeneic Bone Marrow Mesenchymal Stem Cells Transplantation in Patients With Liver Failure Caused by Hepatitis B Virus (HBV)
Status: UNKNOWN
Conditions: Liver Failure
Interventions: OTHER: Group 1|OTHER: Group 2|OTHER: Group 3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety And Efficacy Of Azacitidine, and Lenalidomide In Higher Risk Myelodysplastic Syndrome
Status: UNKNOWN
Conditions: Myelodysplastic Syndrome
Interventions: DRUG: 5-Azacytidine and Lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Total Neoadjuvant Therapy Followed by 'Watch and Wait' Approach or Organ Preservation for Low-risk Rectal Cancer
Status: UNKNOWN
Conditions: Rectum Cancer
Interventions: DRUG: Oxaliplatin|DRUG: Capecitabine|RADIATION: intensity modulated radiotherapy|PROCEDURE: DRE-Endoscopy-MRI-CEA|PROCEDURE: Nonoperative Management|PROCEDURE: Local excision|PROCEDURE: Total Mesorectal Excision|BEHAVIORAL: Quality of Life Questionnaires
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase 2a, Randomized, Placebo Controlled, Study to Evaluate the Safety and Efficacy of AMG 557/MEDI5872 in Primary Sjögren's Syndrome
Status: COMPLETED
Conditions: Primary Sjögren's Syndrome
Interventions: BIOLOGICAL: AMG 557/MEDI5872|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Subcutaneous Abatacept to Treat Diffuse Cutaneous Systemic Sclerosis
Status: COMPLETED
Conditions: Diffuse Cutaneous Systemic Sclerosis
Interventions: DRUG: Abatacept|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Evaluate the Impact of aKwa Skincare System on Skin Health
Status: COMPLETED
Conditions: Sin Health|Skin Hydration|Skin Wrinkles|Skin Porphyrins|Facial Skin Red Spots|Facial Skin Red Vasculature
Interventions: OTHER: äKwä skincare system products|OTHER: competitor products (control)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Bioequivalence Study of L04TD3 Compared to Administration of L04RD1 in Healthy Volunteers
Status: COMPLETED
Conditions: Essential Hypertension
Interventions: DRUG: L04RD1|DRUG: L04TD3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of CC-122 Combined With Sorafenib for Primary Liver Cancer
Status: TERMINATED
Conditions: Carcinoma, Hepatocellular
Interventions: DRUG: CC-122|DRUG: Sorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Efficacy of 3M Dry Mouth Moisturizing Spray
Status: COMPLETED
Conditions: Xerostomia
Interventions: DEVICE: 3M Dry Mouth Moisturizing Spray to Biotene Moisturizing Mouth Spray|DEVICE: Biotene Moisturizing Mouth Spray to 3M Dry Mouth Moisturizing Spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT