pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: HIV Educational Programs for Villagers of Funan County or Yingzhou District, Anhui Province, China
Status: WITHDRAWN
Conditions: HIV Infections
Interventions: BEHAVIORAL: HIV skills training program and questionnaire|BEHAVIORAL: Community-level stigma reduction program|BEHAVIORAL: Cross-sectional survey
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Inotuzumab Ozogamicin Post-Transplant For Acute Lymphocytic Leukemia
Status: RECRUITING
Conditions: Acute Lymphocytic Leukemia
Interventions: DRUG: Inotuzumab Ozogamicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intravitreal Infliximab for Proliferative Vitreoretinopathy
Status: COMPLETED
Conditions: Rhegmatogenous Retinal Detachment|Proliferative Vitreoretinopathy|Retinal Detachment
Interventions: DRUG: Intravitreal infliximab|PROCEDURE: Pars plana vitrectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Cycle Ergometer Training and Heart Failure on Heart Rate Recovery and Mind Fullness
Status: COMPLETED
Conditions: Heart Failure NYHA Class I|Heart Failure NYHA Class II
Interventions: OTHER: Cycle ergometer training|OTHER: Conventional therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study to Evaluate the Tolerance, Pharmacokinetics and Efficacy of TQ-A3334 Tablets
Status: TERMINATED
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: TQ-A3334 tablets|DRUG: TQ-A3334 tablets + Anlotinib capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Palliation of Dyspnea in Advanced Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: DRUG: Opioid (morphine sulphate) in low dose
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Test the Safety of Immunotherapy With Nivolumab Alone or With Ipilimumab Before Surgery for Bladder Cancer Patients Who Are Not Suitable for Chemotherapy
Status: RECRUITING
Conditions: Bladder Cancer
Interventions: DRUG: Nivolumab|DRUG: Ipilimumab|PROCEDURE: Radical cystectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Feasibility Open Trial of App-Enhanced Brief CBT for Suicidal Inpatients
Status: COMPLETED
Conditions: Suicidal and Self-injurious Behavior
Interventions: BEHAVIORAL: App-Enhanced Brief Cognitive-Behavioral Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ipatasertib (GDC-0068) Study to Evaluate Formulation Change and Food Effect on Bioavailability in Healthy Subjects
Status: COMPLETED
Conditions: Cancer
Interventions: DRUG: Ipatasertib (capsule)|DRUG: Ipatasertib (tablet)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Lycra Garments on Spastic Diplegic Cerebral Palsy Patients With Scoliosis
Status: ACTIVE_NOT_RECRUITING
Conditions: Balanced; Rearrangement|Respiratory Function Test
Interventions: DEVICE: Lycra garment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SCREENING
Clinical trial: Melatonin's Effect on Nighttime Blood Pressure and Sleep in OSA Patients (MEBP-OSA)
Status: RECRUITING
Conditions: Obstructive Sleep Apnea of Adult
Interventions: DRUG: Melatonin 3 MG Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Pioglitazone Combination Therapy in Type 2 Diabetes Patients on a Background of Empagliflozin With Metformin
Status: RECRUITING
Conditions: T2DM
Interventions: DRUG: CT-L03-301 Group 1|DRUG: CT-L03-301 Group 2|DRUG: Placebo|DRUG: Empagliflozin|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Primary Pigmented Nodular Adrenocortical Disease (PPNAD) and the CARNEY Complex (CNC)
Status: COMPLETED
Conditions: Primary; Complex|Pigmented Nodular Adrenocortical Disease, Primary, 1|Periorificial Lentiginosis|Cardiac Myxoma
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Use of Finasteride to Reduce Hematuria and Hematospermia Following TRUS Prostate Biopsy
Status: TERMINATED
Conditions: Hematuria|Hematospermia
Interventions: DRUG: Finasteride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: To Demonstrate the Relative Bioequivalency of Generic Haloperidol Tablets Versus Haldol in Normal Volunteers
Status: COMPLETED
Conditions: Psychosis
Interventions: DRUG: Haloperidol 10 mg Tablets (Cord Laboratories)|DRUG: Haldol 10 mg Tablets (McNeil Pharmaceuticals)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Observational Study on Effectiveness and Safety of Integrative Korean Medicine Treatment for Inpatients With Sciatica Due to Lumbar Intervertebral Disc Herniation
Status: COMPLETED
Conditions: Sciatica Due to Intervertebral Disc Disorder|Intervertebral Disc Displacement|Sciatica|Sciatic Radiculopathy
Interventions: DRUG: Herbal medicine|PROCEDURE: Chuna manual therapy|PROCEDURE: Bee venom pharmacopuncture|PROCEDURE: Pharmacopuncture|PROCEDURE: Acupuncture|PROCEDURE: Electroacupuncture|PROCEDURE: Cupping|OTHER: Other intervention(s)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Naproxen for Pain Control With Intrauterine Device Insertion
Status: COMPLETED
Conditions: Contraception
Interventions: DRUG: Naproxen sodium|OTHER: Placebo tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Incidence of Mortality and Complications After Lung Surgery, Open Thoracic Aortic Repair, TEVAR, EVAR.
Status: UNKNOWN
Conditions: Morality|Lung Cancer|Aortic Aneurysm|Aortic Dissection
Interventions: PROCEDURE: Lung surgery|PROCEDURE: Open aortic surgery|PROCEDURE: TEVAR|PROCEDURE: EVAR
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Subcutaneous Anifrolumab in Adult Patients With Systemic Lupus Erythematosus
Status: RECRUITING
Conditions: Systemic Lupus Erythematosus
Interventions: DRUG: Medi-546|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of Sea Grapes-antioxidants Extract in Obese Men : 4 Weeks Randomized-Double Blind Controlled Trial
Status: COMPLETED
Conditions: Obesity|Aging|Diabetes
Interventions: DRUG: Sea grapes extract 1.68 g/70kg BW|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Efficiency and Usability of the Iontophoretic Patch Feeligreen Diclofenac in Treating Acute Osteoarthritic Knee Pain
Status: WITHDRAWN
Conditions: Osteoarthritis
Interventions: DEVICE: Feeligreen patch
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Relapsing Forms of Multiple Sclerosis (RMS) Study of Bruton's Tyrosine Kinase (BTK) Inhibitor Tolebrutinib (SAR442168) (GEMINI 2)
Status: ACTIVE_NOT_RECRUITING
Conditions: Relapsing Multiple Sclerosis
Interventions: DRUG: Tolebrutinib|DRUG: Teriflunomide HMR1726|DRUG: Placebo to match Tolebrutinib|DRUG: Placebo to match Teriflunomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Acute and Subacute Effects of Nicotine Free Electronic Cigarette(NCFE) Vapors
Status: TERMINATED
Conditions: Healthy Lifetime Non-smokers
Interventions: OTHER: Propylene Glycol|OTHER: vegetable glycerin|OTHER: PG+VG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Efficacy of Perifosine Alone and in Combination With Dexamethasone for Patients With Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: perifosine|DRUG: dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vernakalant Versus Amiodarone for Post-operative Atrial Fibrillation in Cardiac Surgery Patients
Status: NOT_YET_RECRUITING
Conditions: Atrial Fibrillation|Post-cardiac Surgery
Interventions: DRUG: Vernakalant|DRUG: Amiodarone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Relative Bioavailability Study of a Prasugrel Orally Disintegrating Tablet
Status: COMPLETED
Conditions: Sickle Cell Disease
Interventions: DRUG: Prasugrel (clinical formulation)|DRUG: Prasugrel (Orally Disintegrating Tablet [ODT])
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PET/MRI in Predicting the Outcome of Neoadjuvant Chemoradiotherapy With Esophagectomy in Esophageal Cancer Patients
Status: COMPLETED
Conditions: Esophageal Cancer
Interventions: DIAGNOSTIC_TEST: PET/MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Aspirin in Colorectal Cancer Liver Metastases
Status: ACTIVE_NOT_RECRUITING
Conditions: Colorectal Cancer Liver Metastases|Colorectal Cancer|Liver Metastases
Interventions: DRUG: Acetylsalicylic acid|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Aspirin on Hemostatic and Vascular Function After Live Fire Fighting
Status: COMPLETED
Conditions: Cardiovascular Risk Factor|C.Medical Procedure; Vascular, Functional or Late|Electrolyte and Fluid Balance Conditions
Interventions: DRUG: 81 mg enteric coated aspirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Negative Pressure Wound Therapy for Surgical Wounds of the Foot and Ankle
Status: COMPLETED
Conditions: Negative Pressure Wound Therapy|Vacuum Therapy|Closed Incisions
Interventions: DEVICE: PICO, Smith & Nephew
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Ultrasound Guided Local Infiltration Analgesia for Hip Arthroscopy
Status: TERMINATED
Conditions: Hip Injuries
Interventions: DRUG: liposomal bupivacaine|DRUG: Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Communicating Multiple Disease Risks: A Translation of Risk Prediction Science
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: BEHAVIORAL: Risk Assessment App|BEHAVIORAL: Audio Recording - Sleep|OTHER: Surveys|BEHAVIORAL: Audio Recording - Exercise|OTHER: Text message reminders|OTHER: Text Message Survey
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: R-CHOP and Alemtuzumab in Patients With Chronic Lymphocytic Leukemia
Status: WITHDRAWN
Conditions: Chronic Lymphocytic Leukaemia|Patients Resistant to a Purine Analogous|Patients Relapsed With Purines Therapy
Interventions: DRUG: Rituximab-CHOP-Alemtuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of the BETACONNECT Auto-injector on BETASERON Therapy Adherence and Patient Satisfaction
Status: COMPLETED
Conditions: Multiple Sclerosis, Relapsing-Remitting
Interventions: DRUG: Interferon beta-1b (Betaseron, BAY86-5046)|DEVICE: BETACONNECT device
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Assess the Safety, Tolerability, and Pharmacokinetics of Cefiderocol in Hospitalized Pediatric Participants
Status: RECRUITING
Conditions: Gram-negative Bacterial Infections|Hospital Acquired Bacterial Pneumonia (HABP)|Complicated Urinary Tract Infection (cUTI)|Ventilator Associated Bacterial Pneumonia (VABP)
Interventions: DRUG: Cefiderocol|DRUG: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Letrozole Versus Gonadotropins in Clomiphene Citrate Resistance
Status: COMPLETED
Conditions: Clomiphene Citrate Resistance|Ovulation Induction|Letrozole|Gonadotropins
Interventions: DRUG: Letrozole 2.5mg|DRUG: Gonadotropin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Vitamin E Supplementation in Methylation and microRNAs Profile
Status: COMPLETED
Conditions: Obesity
Interventions: DIETARY_SUPPLEMENT: vitamin E|DIETARY_SUPPLEMENT: starch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Testing Olaparib and Temozolomide Versus the Usual Treatment for Uterine Leiomyosarcoma After Chemotherapy Has Stopped Working
Status: SUSPENDED
Conditions: Locally Advanced Uterine Corpus Leiomyosarcoma|Metastatic Uterine Corpus Leiomyosarcoma|Stage III Uterine Corpus Leiomyosarcoma AJCC v8|Stage IV Uterine Corpus Leiomyosarcoma AJCC v8|Unresectable Uterine Corpus Leiomyosarcoma
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Bone Scan|PROCEDURE: Computed Tomography|PROCEDURE: Magnetic Resonance Imaging|PROCEDURE: Multigated Acquisition Scan|DRUG: Olaparib|DRUG: Pazopanib|DRUG: Temozolomide|DRUG: Trabectedin|PROCEDURE: Transthoracic Echocardiography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Nitazoxanide, Peginterferon Alfa-2a and Ribavirin for the Treatment of Hepatitis C
Status: COMPLETED
Conditions: Chronic Hepatitis C
Interventions: DRUG: Nitazoxanide|DRUG: Placebo|BIOLOGICAL: Peginterferon alfa-2a|DRUG: Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Two Week Study to Assess the Tolerability of AZD9668 in Chronic Obstructive Pulmonary Disease (COPD) Patients
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: DRUG: AZD9668|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study in Healthy Volunteers to Assess Immune Response to Multiple Injections of Filgrastim Hospira or Neupogen Reference Product.
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: BIOLOGICAL: Filgrastim Hospira|BIOLOGICAL: US-Approved Neupogen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: CBD Oil-Scar Healing Study
Status: NOT_YET_RECRUITING
Conditions: Paramedian Forehead Flap
Interventions: DRUG: Lazarus Naturals THC-Free CBD Tincture (flavorless) + Silicone patch|DRUG: Silicone patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Finacea 15% and Brimonidine 0.33% Gel in the Treatment of Rosacea - A Pilot Study
Status: COMPLETED
Conditions: Acne Rosacea
Interventions: DRUG: Azelaic acid 15%|DRUG: Brimonidine 0.33%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Vaginal Oxytocin Gel on Vaginal Cytologic Parameters in Postmenopausal Woman
Status: TERMINATED
Conditions: Vaginal Atrophy|Oxytocin Gel|Postmenopausal Women|Vaginal Maturation Index
Interventions: DRUG: Oxytocin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Probiotic Lactobacillus Reuteri in the Treatment of Mucositis and Periimplantitis
Status: COMPLETED
Conditions: Mucositis|Peri-implantitis
Interventions: DRUG: Probiotic|DEVICE: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phenylephrine Versus Norepinephrine in Ophthalmic Surgery
Status: COMPLETED
Conditions: Bloodpressure
Interventions: DRUG: phenylephrine|DRUG: norepinephrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Stratified Medicine of Eplerenone in Acute MI/Injury (StratMed-MINOCA)
Status: RECRUITING
Conditions: Myocardial Infarction, Acute|Myocardial Infarction With Nonobstructive Coronary Arteries|Myocardial Injury
Interventions: DRUG: Stratified medicine - Microvascular dysfunction and eplerenone therapy, tablets|OTHER: Stratification and standard care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase II Double-Blind Study of Two Doses of SC-49483 in Combination With Zidovudine (ZDV) Versus ZDV
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Glycovir|DRUG: Zidovudine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Misoprostol for Non-Viable Pregnancies
Status: COMPLETED
Conditions: Abortifacient Agents, Nonsteroidal|Abortion, Incomplete|Misoprostol|Pregnancy
Interventions: DRUG: Misoprostol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Metabolic Changes Induced by a Very Low Carbohydrate Diet in Youth With Type 1 Diabetes
Status: ACTIVE_NOT_RECRUITING
Conditions: Type1diabetes, Low Carbohydrate Diet
Interventions: OTHER: low carbohydrate diet|OTHER: standard carbohydrate diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Is Using Fondaparinux (Blood Thinner) to Treat Lung Clot Cheaper Than Traditional Therapy
Status: WITHDRAWN
Conditions: Pulmonary Embolism
Interventions: DRUG: Fondaparinux
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sonazoid Enhanced Liver Cancer Trial for Early Detection
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma|Liver Cirrhosis|Hepatitis B|Hepatitis C
Interventions: DEVICE: CE-US (Sonazoid™)|DEVICE: B-mode US
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Physical Exercise and Dairy Probiotics in Childhood Cancer Survivors
Status: COMPLETED
Conditions: Acute Lymphoblastic Leukemia, Pediatric
Interventions: OTHER: Lacticaseibacillus paracasei subsp. Paracasei CNCMI-1518|OTHER: Physical exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluating the Clinical Effectiveness of a Patient-specific Silicone Stent
Status: RECRUITING
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DEVICE: Patient-Specific Silicone Airway Stent
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Efficacy and Safety of CF101 to Patients With Osteoarthritis of the Knee
Status: WITHDRAWN
Conditions: Osteoarthritis of the Knee
Interventions: DRUG: CF101|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Dose Range of Remimazolam Besylate in Different Age Groups
Status: RECRUITING
Conditions: Remimazolam|Anesthesia
Interventions: DRUG: Remimazolam besylate|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study To Evaluate Safety, Tolerability, And Pharmacokinetics Of PF-06473871 In Normal Healthy Adults
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: 80 mg PF-06473871|DRUG: 160 mg PF-06473871|DRUG: 320 mg PF-06473871|DRUG: 480 mg PF-06473871
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The First 1,000 Days Program: Maternal-Child Obesity Prevention in Early Life
Status: COMPLETED
Conditions: Overweight and Obesity|Social Determinants of Health|Physical Activity|Sleep|Feeding Behavior|Diet Habit
Interventions: BEHAVIORAL: First 1,000 Days Program Site
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Clinical Evaluation of Nanoionomer Filling in Primary Teeth
Status: COMPLETED
Conditions: Dental Caries
Interventions: PROCEDURE: Dental caries was removed from primary molars and was filled with the recent filling material; Ketac Nano.|PROCEDURE: Dental caries was removed from primary molars and was filled with the conventional filling material;Vitremer
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bronchodilator Effect of Oral Doxofylline and Procaterol in Chronic Obstructive Pulmonary Disease
Status: NOT_YET_RECRUITING
Conditions: COPD
Interventions: DRUG: Doxofylline|DRUG: Procaterol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Topotecan, High-Dose Cyclophosphamide, Carboplatin, and an Autologous Peripheral Blood Cell Transplant in Treating Patients With Recurrent Ovarian Cancer or Primary Peritoneal Cancer
Status: COMPLETED
Conditions: Ovarian Cancer|Peritoneal Cavity Cancer
Interventions: BIOLOGICAL: filgrastim|DRUG: carboplatin|DRUG: cyclophosphamide|DRUG: topotecan hydrochloride|PROCEDURE: autologous hematopoietic stem cell transplantation|PROCEDURE: peripheral blood stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: "Alcohol Based Hand Sanitizers for the Prevention of Acute Diarrheal Disease and Acute Respiratory Infection in Children Under 5 Attending Childcare Centers in Bogotá, Cundinamarca and Tolima, in Colombia: a Cluster Randomized Control Trial"
Status: COMPLETED
Conditions: Acute Diarrheal Disease|Acute Respiratory Infection
Interventions: OTHER: ABHS use
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Methotrexate, Procarbazine, Lomustine, Dexamethasone, and Cytarabine in Treating Patients With Primary CNS Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: DRUG: cytarabine|DRUG: dexamethasone|DRUG: lomustine|DRUG: methotrexate|DRUG: procarbazine hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Postoperative Cognitive Dysfunction in Elderly Urologic Oncology Patients (POCD)
Status: UNKNOWN
Conditions: Postoperative Cognitive Dysfunction|Postoperative Delirium|Frailty
Interventions: DEVICE: Near Infrared Spectroscopy (NIRS)|DIAGNOSTIC_TEST: Blood sample|DIAGNOSTIC_TEST: Addenbrooke Cognitive Examination III (ACE-III)|DIAGNOSTIC_TEST: Confusion Assessment Method
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Aprepitant for Chemotherapy Induced Nausea and Vomiting in Chinese Advanced Non-small Cell Lung Cancers
Status: COMPLETED
Conditions: Carcinoma, Non-small Cell Lung
Interventions: DRUG: Aprepitant|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Developing and Testing of Culturally Adapted Cognitive Behavior Therapy (CaCBT) for Pashto Speaking Pakistanis and Afghans
Status: COMPLETED
Conditions: Depression, Anxiety
Interventions: OTHER: CaCBT|OTHER: Medication/ Psychotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of CG-806 in Patients With Relapsed or Refractory AML or Higher-Risk MDS
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Myeloid Leukemia|Myelodysplastic Syndromes
Interventions: DRUG: CG-806
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Perfusion Index Predicts Post-spinal Hypotension in Obese Parturients for Cesarean Section
Status: COMPLETED
Conditions: Perfusion Index Predicts Post-spinal Hypotension
Interventions: PROCEDURE: correlation between baseline perfusion index and decrease in systolic blood pressure post spinal induction
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Impact of Preoperative Oral Glutamine Intake on the Immunocompetence and Outcomes of Malnourished Patients Undergoing Major Abdominal Surgery Due to Malignancies
Status: COMPLETED
Conditions: Malnourishment|Gastrointestinal Tumors
Interventions: DIETARY_SUPPLEMENT: Glutamine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: OptiMesh® for Lumbar Interbody Fusion Trial (OLIF)
Status: COMPLETED
Conditions: Degeneration of Lumbar Intervertebral Disc
Interventions: DEVICE: Structural Allograft Spacer|DEVICE: OptiMesh 1500S
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Markerless Image Guidance Using Intrafraction Kolovoltage X-ray Imaging for Lung Cancer Radiotherapy
Status: RECRUITING
Conditions: Lung Cancer|Markerless Image Guidance|Intrafraction Kolovoltage X-ray Imaging
Interventions: RADIATION: Markerless Tumour Tracking
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Assessment of the Impact on the Quality of Life of Surgically Assisted Maxillary Expansion in Adult Patients Followed for Obstructive Sleep Apnea Syndrome
Status: RECRUITING
Conditions: Obstructive Sleep Apnea
Interventions: OTHER: Filling the Quebec Sleep Questionnaire
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Safety and Exploratory Efficacy Study of UCMSCs in Patients With Ischemic Heart Disease (SEESUPIHD)
Status: UNKNOWN
Conditions: Acute Myocardial Infarction|Myocardial Infarction|Ischemic Cardiomyopathy
Interventions: BIOLOGICAL: umbilical cord mesenchymal stem cells
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Trial of Hydrus Microstent Versus Goniotomy
Status: NOT_YET_RECRUITING
Conditions: Glaucoma|Glaucoma, Open-Angle
Interventions: PROCEDURE: Hydrus Microstent|PROCEDURE: Incisional goniotomy|PROCEDURE: Excisional goniotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study in Healthy Volunteers and Patients With Chronic Hepatitis B
Status: COMPLETED
Conditions: Chronic Hepatitis B
Interventions: DRUG: ABI-H0731|DRUG: Placebo for ABI-H0731|DRUG: Entecavir|DRUG: Tenofovir disoproxil fumarate|DRUG: Pegasys|DRUG: Nucleos(t)ide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cardio-respiratory Events in Preterm Infants During Transition
Status: COMPLETED
Conditions: Apnea of Prematurity|Apneic Spells of Newborn Nos|Patent Ductus Arteriosus|Premature Birth|Desaturation of Blood|Bradycardia Neonatal
Interventions: DEVICE: pulse oximetry monitoring
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The SWOAR Trial Sparing of Swallowing and Aspiration Related Organs at Risk & Submandibular Gland With Intensity Modulated Radiotherapy Versus Standard IMRT in Head and Neck Squamous Cell Carcinomas
Status: RECRUITING
Conditions: Head and Neck Neoplasms|Swallowing Sparing IMRT
Interventions: RADIATION: Swallowing and submandibular sparing IMRT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Information and Acceptability of Biosimilars
Status: RECRUITING
Conditions: Rheumatoid Arthritis|Spondyloarthritis|Psoriatic Arthritis
Interventions: OTHER: Generic information leaflet|OTHER: Individual information by nurse on biosimilars
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: An Epidemiological Survey to Establish the Spectrum of Circulating Serotypes of S. Pneumoniae, in Patients Older 18 Years
Status: COMPLETED
Conditions: Pneumonia, Pneumococcal|Invasive Pneumococcal Disease|Acute Otitis Media
Interventions: OTHER: Detection of Streptococcus pneumoniae strains
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: A Study of An Approved Vaccine at Mumps Expiry Potency in Healthy Children 12 to 18 Months of Age (V205C-007)(COMPLETED)
Status: COMPLETED
Conditions: Measles|Mumps|Rubella|Varicella
Interventions: BIOLOGICAL: Comparator: M-M-R(TM) II, measles, mumps, and rubella virus vaccine live|BIOLOGICAL: Comparator: VARIVAX(TM) Varicella Virus Vaccine Live (Oka-Merck)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: ISe-santé, a Study Evaluating a Model for Implementing E-health in the Management of HIV Patients
Status: UNKNOWN
Conditions: HIV|Telemedicine
Interventions: OTHER: Teleconsultation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Pudendal Nerve Block for Postoperative Posterior Repair Pain Relief
Status: COMPLETED
Conditions: Pelvic Organ Prolapse
Interventions: DRUG: Pudendal Nerve Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Dexmedetomidine During Radiofrequency Ablation of Abdominal Tumours
Status: COMPLETED
Conditions: Cancer of Kidney and Renal Pelvis|Cancer of Liver
Interventions: DRUG: Dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Feasibility Study of Gallium-68 Citrate PET to Detect Aberrant MYC Proto-Oncogene, BHLH Transcription Factor (MYC) Protein Expression in Diffuse Large B-Cell Lymphoma
Status: WITHDRAWN
Conditions: Lymphoma, Large B-Cell, Diffuse|Burkitt Lymphoma
Interventions: DRUG: Gallium citrate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effects of Tolcapone on Frontotemporal Dementia
Status: COMPLETED
Conditions: Frontotemporal Lobar Degeneration
Interventions: DRUG: Tolcapone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare FKB327 Efficacy and Safety With Humira® in Rheumatoid Arthritis Patients
Status: COMPLETED
Conditions: Arthritis, Rheumatoid
Interventions: DRUG: FKB327|DRUG: Humira®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase II Dose-Ranging, Open-Labelled Trial of Foscarnet Salvage Therapy for AIDS Patients With Sight-Threatening CMV Retinitis Who Cannot Be Treated With Ganciclovir Due To Myelosuppression or Treatment Failure
Status: COMPLETED
Conditions: Cytomegalovirus Retinitis|HIV Infections
Interventions: DRUG: Foscarnet sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Pre-Exposure Prophylaxis (PrEP)- Gender Affirming Hormone Therapy (GAHT) Interactions in TGW
Status: RECRUITING
Conditions: Hiv|Prophylaxis|Transgender
Interventions: DRUG: Truvada alone|DRUG: Truvada plus Leuprolide|DRUG: Truvada plus Estradiol 1 mg|DRUG: Truvada plus Estradiol 6 mg|DRUG: Estradiol 6 mg alone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Improving Arm Function Using Wearable Exoskeletons
Status: NOT_YET_RECRUITING
Conditions: Hemiparesis; Poststroke/CVA
Interventions: DEVICE: Wearable Shoulder Exoskeleton|DEVICE: Wearable Hand Exoskeleton
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Effect of Different Virtual Reality Trainings on Gait, Balance and Posture of Individuals With Dementia
Status: COMPLETED
Conditions: Dementia
Interventions: OTHER: exergame|OTHER: exergame|OTHER: exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of rHuTPO on Platelet Engraftment After Allo-HSCT
Status: UNKNOWN
Conditions: Allogeneic Hematopoietic Stem Cell Transplantation|Myeloablative|Delayed Platelet Engraftment
Interventions: DRUG: Recombinant Human Thrombopoietin (rHTPO)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Promotion of Sleep for Patients Submitted to Percutaneous Intervention to Treat Heart Diseases
Status: UNKNOWN
Conditions: Sleep Hygiene
Interventions: DEVICE: Intervention to decrease disruptive sleep in patients undergoing percutaneous intervention to treat cardiac disorders admitted to the ICU: ear protector and eye mask.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Effect of a High Calcium Breakfast on Exercise Metabolism and Appetite
Status: COMPLETED
Conditions: Exercise Fat Oxidation
Interventions: DIETARY_SUPPLEMENT: High calcium milk|DIETARY_SUPPLEMENT: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Zinc Supplementation in Sickle Cell Disease
Status: NOT_YET_RECRUITING
Conditions: Sickle Cell Disease
Interventions: DRUG: 25 mg/day zinc|DRUG: 40 mg/day zinc
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Evaluation of a Stepped Care Approach to Manage Depression in Diabetes
Status: COMPLETED
Conditions: Major Depressive Disorder|Minor Depressive Disorder|Sub-Threshold Depression|Diabetes Mellitus
Interventions: BEHAVIORAL: Step 1: Diabetes-Specific CBT (5 group sessions)|BEHAVIORAL: Step 2: Depression-Specific CBT (6 single sessions)|BEHAVIORAL: Step 3: Referral to Psychotherapist and/or Psychiatrist|BEHAVIORAL: Standard Diabetes Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prognostic Value of the Right Ventricular Function by Portable Ultrasound in Patients With Pulmonary Hypertension.
Status: UNKNOWN
Conditions: Pulmonary Hypertension|Pulmonary Arterial Hypertension|Cardiac Ultrasound
Interventions: DEVICE: cardiac ultrasound
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety & Efficacy of Omega-3 Fish Oil in Overweight Children & Adolescents
Status: TERMINATED
Conditions: Overweight|Obesity
Interventions: DRUG: Supplement: Omega-3 Fish Oil|BEHAVIORAL: Multi-Disciplinary Nutrition & Exercise program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Oxytocin vs. Placebo for the Treatment Hyperphagia in Children and Adolescents With Prader-Willi Syndrome
Status: COMPLETED
Conditions: Prader-Willi Syndrome|Hyperphagia
Interventions: DRUG: Intranasal Oxytocin (IN-OXT)|OTHER: Matched Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Safety and Tolerability Study OF PUR118 In Subjects With Cystic Fibrosis
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: PUR118
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A 3-Month Clinical Trial to Assess the Safety and Efficacy of the OZURDEX® Intraocular Implant in Patients With Diabetes Mellitus
Status: COMPLETED
Conditions: Macular Edema|Diabetes Mellitus
Interventions: DRUG: Dexamethasone intravitreal implant|DRUG: Steroid plus NSAID eye drop combination therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Efficacy and Safety of LO2A Eye Drops in Patients With Moderate to Severe Conjunctivochalasis
Status: COMPLETED
Conditions: Conjunctivochalasis
Interventions: DRUG: LO2A|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vision Restoration Therapy (VRT) to Treat Non-Arteritic Anterior Ischemic Optic Neuropathy
Status: COMPLETED
Conditions: Non-Arteritic Anterior Ischemic Optic Neuropathy
Interventions: DEVICE: Vision Restoration Therapy (NOVAVISION)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Long Term Extension Study Evaluating Safety, Tolerability And Immunogenicity Of ACC-001 In Japanese Subjects With Mild To Moderate Alzheimer's Disease
Status: TERMINATED
Conditions: Alzheimer's Disease
Interventions: BIOLOGICAL: ACC-001|BIOLOGICAL: ACC-001|BIOLOGICAL: ACC-001
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: No Treatment Versus Oral Ibuprofen Treatment for Patent Ductus Arteriosus in Preterm Infants
Status: COMPLETED
Conditions: Bronchopulmonary Dysplasia (BPD)
Interventions: DRUG: Oral ibuprofen|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating Single Ascending Doses of AAB-001 Vaccine SAD Japanese Patients With Alzheimers Disease
Status: COMPLETED
Conditions: Alzheimer Disease
Interventions: DRUG: bapineuzumab|DRUG: bapineuzumab|DRUG: bapineuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Pre-Operative Effects of Mifepristone on Dilation and Evacuation Services
Status: COMPLETED
Conditions: Legally Induced Abortion Without Mention of Complication
Interventions: OTHER: Hygroscopic cervical dilators|DRUG: Misoprostol|DRUG: Intra-amniotic digoxin|DRUG: Mifepristone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Long-term Benefits of Abdominal Fat Loss in Abdominally Obese Dyslipidemic Patients (SYNERGIE Study)
Status: COMPLETED
Conditions: Obesity, Visceral|Diet, Healthy|Cardiometabolic Syndrome|Lifestyle-related Condition
Interventions: BEHAVIORAL: Lifestyle modification program
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Prevention of Substance Use in At-Risk Students: A Family-Centered Web Program
Status: COMPLETED
Conditions: Substance Use|Conduct Disorders in Adolescence|Depression|Anxiety
Interventions: BEHAVIORAL: FCU-Online, web/ mobile only|BEHAVIORAL: FCU-Online, web/ mobile + coach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: COVID-19 Subcutaneously and Orally Administered Supplemental Vaccine Boost to Enhance T Cell Protection in Those Who Have Already Received EUA S-Based Vaccines
Status: WITHDRAWN
Conditions: Covid19
Interventions: BIOLOGICAL: hAd5-S-Fusion+N-ETSD vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1/2 Study of CAN04 in Combination With Different Chemotherapy Regimens in Subjects With Advanced Solid Tumors
Status: COMPLETED
Conditions: Advanced Solid Tumors|Colorectal Cancer|Non Small Cell Lung Cancer|Biliary Tract Cancer
Interventions: DRUG: CAN04 (nadunolimab)|DRUG: mFOLFOX|DRUG: DTX|DRUG: G/C
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Subthreshold Nanosecond Laser for Non-resolving Central Serous Chorioretinopathy
Status: RECRUITING
Conditions: Central Serous Chorioretinopathy
Interventions: DEVICE: 2RT subthreshold nanosecond laser - active|DEVICE: 2RT subthreshold nanosecond laser - sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: BAX 855 Pediatric Study
Status: COMPLETED
Conditions: Hemophilia A
Interventions: BIOLOGICAL: Antihemophilic Factor (Recombinant) - Plasma/Albumin Free Method|BIOLOGICAL: PEGylated Recombinant Factor VIII|BIOLOGICAL: PEGylated Recombinant Factor VIII
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of CC-99677 in Healthy Adult Japanese Participants.
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: CC-99677|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Oral Hygiene Gels on Peri-implant Mucositis
Status: COMPLETED
Conditions: Mucositis
Interventions: OTHER: Livionex gel|OTHER: Aquafresh gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of the Immunogenicity and Safety of a Dose-Sparing BioThrax® AVA Schedule
Status: COMPLETED
Conditions: Bacillus Anthracis (Anthrax)
Interventions: BIOLOGICAL: BioThrax®|BIOLOGICAL: BioThrax®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Autogenic Inhibition Versus Reciprocal Inhibition Muscle Energy Techniques Effect on Swimming Performance on Swimmers With Scapular Dyskinesis
Status: RECRUITING
Conditions: Scapular Dyskinesis
Interventions: PROCEDURE: Autogenic Inhibition-MET|PROCEDURE: Reciprocal Inhibition-MET protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Accelerated TMS to a Novel Brain Target in MDD and PTSD
Status: COMPLETED
Conditions: Post Traumatic Stress Disorder|Major Depressive Disorder
Interventions: DEVICE: Transcranial Magnetic Stimulation (TMS)|BEHAVIORAL: Task|PROCEDURE: fMRI-guided TMS target
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: The Effects of LAF237 on Gastric Function in Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Non-Insulin-Dependent
Interventions: DRUG: LAF237 = vildagliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT