pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Clopidogrel for High Atherothrombotic Risk and Ischemic Stabilization, Management and Avoidance (CHARISMA)
Status: COMPLETED
Conditions: Arteriosclerosis
Interventions: DRUG: clopidogrel (SR25990)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: PES to Avoid Extubation Failure in Intubated Stroke Patients at High Risk of Severe Dysphagia
Status: UNKNOWN
Conditions: Stroke|Dysphagia|Extubation Failure
Interventions: DEVICE: Pharyngeal Electrical Stimulation (PES)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Home-based Psychoeducation for Older Adults With Frailty: A Feasibility Trial
Status: COMPLETED
Conditions: Frailty|Well-Being, Psychological
Interventions: OTHER: Psychoeducation|OTHER: Attention control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Geniculate Artery Embolization for Treatment of Persistent Knee Pain Post Total Knee Arthroplasty
Status: RECRUITING
Conditions: Knee Pain
Interventions: DEVICE: Embozene Color-Advanced Microspheres.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Home Based Transcranial Direct Current Stimulation (tDCS) With Exercise on Upper and Lower Limb Motor Functions in Chronic Stroke
Status: COMPLETED
Conditions: Transcranial Direct Current Stimulation|Chronic Stroke
Interventions: DEVICE: Transcranial direct current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Post-operative Pain Control With Acetaminophen and Ibuprofen After Functional Endoscopic Sinus Surgery
Status: NOT_YET_RECRUITING
Conditions: Chronic Rhinosinusitis (Diagnosis)
Interventions: OTHER: Comparison of medication administration for pain control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of BGB324(Bemcentinib) in Combination With Erlotinib in Patients With Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: erlotinib|DRUG: bemcentinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preoperative High Dose Steroids for Liver Resection- Effect on Complications in the Immediate Postoperative Period
Status: COMPLETED
Conditions: Complication, Postoperative
Interventions: DRUG: Methylprednisolone|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Impact of Transcutaneous Spinal Cord Stimulation (TSCS) and Gait Training on Walking Function in Patients With Spinal Cord Injury
Status: COMPLETED
Conditions: Spinal Cord Injuries
Interventions: OTHER: Transcutaneous Spinal Cord Stimulation and Gait Training
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Endovascular Treatment for Mild Stroke With Acute Anterior Circulation Large Vessel Occlusion
Status: RECRUITING
Conditions: Endovascular Treatment
Interventions: OTHER: Experimental group:Intervention Group|OTHER: Control group:best medical treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: S0716 Vandetanib and Docetaxel in Treating Patients With Advanced Solid Tumors
Status: WITHDRAWN
Conditions: Breast Cancer|Head and Neck Cancer|Lung Cancer|Prostate Cancer|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: docetaxel|DRUG: vandetanib|GENETIC: proteomic profiling|OTHER: laboratory biomarker analysis|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cortical Stimulation to Treat Mood and Behavioral Symptoms in Parkinson's Disease Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Parkinson's Disease
Interventions: DEVICE: Activa PC+S Prefrontal
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bone Toxicity Following Pelvic Radiotherapy
Status: ACTIVE_NOT_RECRUITING
Conditions: Gynecologic Cancer|Radiotherapy Side Effect|Fracture
Interventions: COMBINATION_PRODUCT: Musculoskeletal health package
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PERFECT Project - Part 2 - Study 1
Status: COMPLETED
Conditions: Diabetes|Obesity
Interventions: OTHER: Control|OTHER: Small particle size pea flour|OTHER: Large particle size pea flour|OTHER: Lentil flour|OTHER: Navy bean flour|OTHER: Pinto bean flour
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Ejaculatory Sparing Transurethral Incision Of The Prostate (ES-TUIP) Versus Conventional TUIP
Status: UNKNOWN
Conditions: Prostate Hyperplasia|Transurethral Incision Of The Prostate|Ejaculatory Dysfunction
Interventions: PROCEDURE: Ejaculatory sparing TUIP|PROCEDURE: Conventional TUIP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Ketamine and Neuropathic Pain
Status: UNKNOWN
Conditions: Neuropathic Pain
Interventions: DRUG: Ketamine|DRUG: Magnesium Sulfate|DRUG: placebo : sodium chloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Tunneling During Minimally Invasive Sacrocolpopexy
Status: COMPLETED
Conditions: Lower Urinary Tract Symptoms|Lower Gastrointestinal Tract Symptoms
Interventions: PROCEDURE: tunneling|PROCEDURE: non-tunneling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Icotinib as First-line and Maintenance Treatment in EGFR Mutated Patients With Lung Adenocarcinoma
Status: UNKNOWN
Conditions: EGFR Positive Non-small Cell Lung Cancer|Adenocarcinoma
Interventions: DRUG: Experimental|DRUG: Chemotherapy|DRUG: Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Celecoxib Versus Diclofenac In The Treatment Of Osteoarthritis Of The Hip
Status: COMPLETED
Conditions: Osteoarthritis, Hip
Interventions: DRUG: Celecoxib|DRUG: Diclofenac
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Investigation of Otelixizumab in New-Onset, Autoimmune Type 1 Diabetes Mellitus Patients
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: BIOLOGICAL: Otelixizumab|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Effectiveness of a Nasal Spray to Treat Seasonal Allergies
Status: COMPLETED
Conditions: Seasonal Allergic Rhinitis
Interventions: DRUG: MP29-02|DRUG: azelastine Hcl|DRUG: fluticasone propionate|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pelvic Floor Dysfunction and Quality of Life in Uterine Cancer Survivors
Status: ACTIVE_NOT_RECRUITING
Conditions: Endometrial Carcinoma|Malignant Uterine Neoplasm|Uterine Corpus Cancer|Uterine Corpus Sarcoma
Interventions: OTHER: Questionnaire Administration
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of ITCA 650 (Exenatide in DUROS) in Subjects With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: OTHER: ITCA 650|DRUG: Exenatide Injection|OTHER: Ex Inj/ITCA 650
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cryoablation for Monomorphic Ventricular Tachycardia (CryoCure-VT)
Status: ACTIVE_NOT_RECRUITING
Conditions: Monomorphic Ventricular Tachycardia
Interventions: DEVICE: Ablation in the ventricles with the Adagio Medical VT Cryoablation System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Helium-Neon Laser Therapy Versus Infrared Laser Therapy in Treating Patients With Diabetic Foot Ulcer
Status: COMPLETED
Conditions: Diabetic Mellitus|Laser
Interventions: OTHER: Helium Neon Laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ascending Dose Study of HU6 in Healthy Volunteers
Status: COMPLETED
Conditions: NASH - Nonalcoholic Steatohepatitis
Interventions: DRUG: HU6
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Pacemaker Algorithms to Avoid Unnecessary Right Ventricular Pacing
Status: COMPLETED
Conditions: Pacemaker Implantation for Sinus Node Disease
Interventions: OTHER: pacemaker programming to mode switch to atrial pacing versus atrioventricular hysteresis function
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Developing a Nationwide Registry to Track Longitudinal Clinical Outcomes of Corneal Surgery and Disease
Status: RECRUITING
Conditions: Corneal Disease|Endothelial Corneal Dystrophy|Corneal Transplant Failure|Corneal Transplant Rejection
Interventions: DIAGNOSTIC_TEST: Optical Coherence Tomography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Bevacizumab + CHOP-Rituximab in Untreated Mantle Cell Lymphoma
Status: COMPLETED
Conditions: Untreated Mantle Cell Lymphoma
Interventions: DRUG: Bevacizumab|DRUG: Rituximab|DRUG: CHOP
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: DoVe Trial: Dorsal Onlay Versus Ventral Onlay in Isolated Bulbar Urethral Strictures
Status: RECRUITING
Conditions: Urethra Stenosis
Interventions: PROCEDURE: Free graft urethroplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Impact of iv Dexamethasone on Reversal of Rocuronium-induced Neuromuscular Block by Sugammadex
Status: WITHDRAWN
Conditions: Neuromuscular Blockade
Interventions: DRUG: Normal saline|DRUG: IV dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Conscious Dying/Conscious Living: Ketamine-Assisted Psychotherapy
Status: UNKNOWN
Conditions: Illness Terminal
Interventions: DRUG: Ketamine Injectable Solution|OTHER: Naturalistic Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Aerobic Plus Resistance Training and Insulin Sensitivity in African American Men
Status: UNKNOWN
Conditions: Insulin Resistance|Type 2 Diabetes
Interventions: BEHAVIORAL: Aerobic Plus Resistance Training Group|BEHAVIORAL: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Improvement of Immunologic and Molecular Techniques for the Diagnosis and Follow-up of Patients With Thrombotic Thrombocytopenic Purpura
Status: RECRUITING
Conditions: Acquired Thrombotic Thrombocytopenic Purpura
Interventions: DEVICE: ADAMTS13 Activity Assays
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Theca Cell Function in Women With Polycystic Ovary Syndrome (PCOS)
Status: COMPLETED
Conditions: Polycystic Ovary Syndrome
Interventions: DRUG: recombinant human chorionic gonadotropin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Pembrolizumab With Sitravatinib in Recurrent Endometrial Cancer and Other Solid Tumors With Deficient Mismatch Repair System
Status: WITHDRAWN
Conditions: Recurrent Endometrial Cancer|Solid Tumors
Interventions: DRUG: pembrolizumab|DRUG: Sitravatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant PRRT With Y-90-DOTATOC in pNET
Status: UNKNOWN
Conditions: Pancreatic Neuroendocrine Tumor
Interventions: OTHER: peptide receptor radionuclide therapy with Y-90-DOTATOC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Cognitive-Behavioral Therapy for Chronic Insomnia After Breast Cancer Treatment
Status: COMPLETED
Conditions: Breast Cancer
Interventions: BEHAVIORAL: Cognitive Behavioral Therapy for Insomnia (CBTI)|BEHAVIORAL: Behavioral Placebo Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Prediction of Spinal Anesthesia-Induced Hypotension in Cesarian Section: Carotid Artery-Corrected Flow Time Versus Cardiometry
Status: COMPLETED
Conditions: Spinal Anesthesia|Hypotension|Cesarian Section|Carotid Artery|Corrected Flow Time|Cardiometry
Interventions: OTHER: Carotid Ultrasound|OTHER: Electrical cardiometry
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Thermal Micro-cautery for Painful Knee Osteoarthritis
Status: COMPLETED
Conditions: Chronic Pain Syndrome
Interventions: OTHER: Peripheral Nerve Field Stimulation by Thermal Micro-Cautery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trametinib for Pediatric Neuro-oncology Patients With Refractory Tumor and Activation of the MAPK/ERK Pathway.
Status: ACTIVE_NOT_RECRUITING
Conditions: Low-grade Glioma|Plexiform Neurofibroma|Central Nervous System Glioma
Interventions: DRUG: Trametinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Effect of the Aerobika Device in Addition to Standard of Care Treatment in Sputum Producing COPD Patients Using FRI
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive|COPD
Interventions: DEVICE: Aerobika® Device|RADIATION: HRCT scans
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study to Assess the Efficacy and Safety of a Healing Ointment on Diaper Rash
Status: COMPLETED
Conditions: Diaper Rash
Interventions: DRUG: "Cetaphil Healing Ointment"
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Treatment of NAs and Peg IFN α-2b for Hepatitis B Related, Compensatory Cirrhosis Patients
Status: UNKNOWN
Conditions: Cirrhosis of Liver Due to Hepatitis B (Disorder)
Interventions: DRUG: pegylated interferon (Peg IFN)α-2b|DRUG: Nucleoside （acid）analogue (NAs)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CBP-201 in Adolescent and Adult Patients With Moderate-to-severe Atopic Dermatitis
Status: WITHDRAWN
Conditions: Atopic Dermatitis
Interventions: DRUG: CBP-201|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Different Subsequent Treatments After Radical Surgery
Status: UNKNOWN
Conditions: Cervical Cancer
Interventions: RADIATION: Radiotherapy (RT)|OTHER: Concurrent chemoirradiation (CCRT)|OTHER: Sequence chemotherapy and radiotherapy (SCRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multiparametric Assessment to Investigate Prognostic Factors for Disease Evolution a nd Evolutionary Patterns of Cognitive Status in RRMS
Status: RECRUITING
Conditions: Multiple Sclerosis, Relapsing-Remitting
Interventions: OTHER: Multiparametric assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Evaluation of Two Methods of Administration of Photobiomodulation in the Context of the Prevention and Treatment of Mucositis Induced by Radiotherapy, During the Treatment of Head and Neck Cancers
Status: NOT_YET_RECRUITING
Conditions: Head and Neck Neoplasms
Interventions: DEVICE: Photobiomodulation session - intraoral|DEVICE: Photobiomodulation session - transcutaneous
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Quantitative Assessment of BB-02 Therapy Effect on Cartilage Status in Patients Affected by Early Knee Osteoarthritis
Status: NOT_YET_RECRUITING
Conditions: Osteoarthritis, Knee
Interventions: DEVICE: BB-02 therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phototherapy and Radiofrecuency for Cellulite
Status: SUSPENDED
Conditions: Cellulite
Interventions: DEVICE: Sanae method with LED|DEVICE: Sanae method with Radiofrecuency
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: NKTR-255 vs Placebo Following CD19-directed CAR-T Therapy in Patients With Relapsed/Refractory Large B-cell Lymphoma
Status: RECRUITING
Conditions: Non-Hodgkin Lymphoma|Relapsed/Refractory Diffuse Large B-cell Lymphoma
Interventions: DRUG: NKTR-255 at 1.5 µg/kg|DRUG: NKTR-255 at 3.0 μg/kg|DRUG: NKTR-255 at 3.0/6.0 μg/kg|OTHER: Placebo Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cellulose Triacetate Dialyzer in Hemodiafiltration-online
Status: COMPLETED
Conditions: Chronic Kidney Disease Requiring Chronic Dialysis
Interventions: DEVICE: Asymmetric cellulose triacetate (ATA™)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Prospective Study on the Tolerability and Efficacy of the de Novo Use of Myfortic in Liver Transplant Recipients
Status: COMPLETED
Conditions: Immunosuppression
Interventions: DRUG: Myfortic|DRUG: CellCept
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of L-Citrulline on Vascular Function
Status: COMPLETED
Conditions: Citrulline|Blood Flow|Aging
Interventions: DIETARY_SUPPLEMENT: L-citrulline|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Brain Circuitry Therapeutics for Schizophrenia
Status: NOT_YET_RECRUITING
Conditions: Schizophrenia; Psychosis
Interventions: DEVICE: iTBS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Guidelines to Practice: Reducing Asthma Health Disparities Through Guideline Implementation
Status: UNKNOWN
Conditions: Asthma
Interventions: BEHAVIORAL: Enhanced Clinic+ Unified Plan + CHW|BEHAVIORAL: Enhanced Clinic+ Unified Management Plan|BEHAVIORAL: CHW Home Visit Only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose:
Clinical trial: Open-label Study to Evaluate Safety, Tolerability and PK of BHV-0223 in ALS
Status: COMPLETED
Conditions: Amyotrophic Lateral Sclerosis|ALS|Lou Gehrig Disease|Lou Gehrig's Disease|Lou-Gehrigs Disease|Motor Neuron Disease, Amyotrophic Lateral Sclerosis
Interventions: DRUG: BHV-0223
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open-Label Study to Evaluate Safety and Efficacy of CCX168 in Subjects With IGA Nephropathy on Stable RAAS Blockade
Status: COMPLETED
Conditions: Immunoglobulin A Nephropathy
Interventions: DRUG: CCX168
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral Health Policy for Patients With Type 2 Diabetes Mellitus in Chile: A Microsimulation Model Based on Real-world Data
Status: ACTIVE_NOT_RECRUITING
Conditions: Type 2 Diabetes Mellitus|Periodontitis|Diabetic Complication|Dental Care
Interventions: PROCEDURE: Periodontal treatment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: MultiPulse Therapy (MPT) for AF
Status: TERMINATED
Conditions: Atrial Fibrillation, Paroxysmal|Atrial Fibrillation, Persistent|Atrial Fibrillation
Interventions: DEVICE: Multi Pulse Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Identification of Gut Microbiome Biomarkers Associated to Acquisition of Enterobacteriae Highly Resistant to Third Generation Cephalosporines Following Ceftriaxone Treatment.
Status: TERMINATED
Conditions: Patients Receiving Ceftriaxone in Hospital Emergency Unit
Interventions: OTHER: Rectal swab collection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of the Safety and Tolerability of a Higher Potency Dose of an Investigational Vaccine Among Adults 50 Years of Age and Older (V211-009)
Status: COMPLETED
Conditions: Healthy
Interventions: BIOLOGICAL: Comparator: Varicella Zoster Virus Vaccine|BIOLOGICAL: Comparator: Varicella Zoster Virus Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Accuracy of Detection Using ENdocuff Optimisation of Mucosal Abnormalities
Status: UNKNOWN
Conditions: Colorectal Neoplasms|Colonic Polyps|Adenoma
Interventions: DEVICE: Endocuff Vision
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety and Efficacy of CERE-120 in Subjects With Parkinson's Disease
Status: COMPLETED
Conditions: Idiopathic Parkinson's Disease
Interventions: BIOLOGICAL: CERE-120: Adeno-Associated Virus Delivery of Neurturin|PROCEDURE: Sham Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: HIgh Dose Thymoglobulin Instead of Cyclosporine With a Low Dose of Thymoglobulin for GVHD Prophylaxis
Status: RECRUITING
Conditions: Graft-versus-host-disease|Relapse
Interventions: DRUG: Treatment Arm - high dose ATG|DRUG: Control Arm - standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigations of Mechanisms and Treatment in Post-traumatic Joint Contractures
Status: COMPLETED
Conditions: Joint Contractures
Interventions: DRUG: Ketotifen|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Dimensional Changes Following Immediate Implant Placement in Molar Extraction Sockets With or Without Bone Graft
Status: NOT_YET_RECRUITING
Conditions: Immediate Implants
Interventions: PROCEDURE: Immediate implant placement + customized healing abutment|PROCEDURE: Immediate implant placement + xenogeneic bone graft material + customized healing abutment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Tissue Adhesive vs. Sterile Strips After Cesarean Delivery
Status: TERMINATED
Conditions: Wound Complication|Complications; Cesarean Section
Interventions: DEVICE: Tissue Adhesive|DEVICE: Sterile strips
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Phase II Study of Simvastatin for Relapsed/Refractory Myeloma
Status: WITHDRAWN
Conditions: Myeloma
Interventions: DRUG: Simvastatin,Zoledronic Acid,Bortezomib,Bendamustine,Methylprednisolone.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study of Fludarabine Plus Cyclophosphamide in Refractory Severe Aplastic Anemia
Status: COMPLETED
Conditions: Aplastic Anemia|Neutropenia|Pancytopenia|Severe Aplastic Anemia
Interventions: DRUG: Cyclophosphamide|DRUG: Fludarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Rye Crisp Bread on Appetite and Metabolic Function
Status: COMPLETED
Conditions: Appetite Regulation
Interventions: OTHER: Rye crisp bread A|OTHER: Rye crisp bread B|OTHER: Wheat crisp bread C
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Role of Uttarbasti in the Management of Mutra Marga Sankoch (Urethral Stricture)
Status: COMPLETED
Conditions: Urethral Stricture
Interventions: PROCEDURE: uttarbasti (per urethral administration of medicated oil )
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Placebo-Controlled Trial of Modafinil (Provigil) Added to Clozapine in Patients With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: modafinil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Intravenous Lidocaine on the Tolerability of Early Oral Feeding After Laparoscopic Colorectal Surgery
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: Lidocaine|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Diaphragmatic Ultrasound as a Predictor of Mechanical Ventilation in Patients With Respiratory Diseases on Admission to Intensive Care Unit
Status: NOT_YET_RECRUITING
Conditions: Respiratory Disease
Interventions: PROCEDURE: Diaphragmatic ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: IMPACT-CABG Trial: IMPlantation of Autologous CD133+ sTem Cells in Patients Undergoing CABG
Status: COMPLETED
Conditions: Myocardial Infarct|Heart Failure
Interventions: PROCEDURE: Injection of stem cells at time of coronary artery bypass grafting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of the Analgesic Effects of PF-06372865 in Healthy Volunteers Using Evoked Pain Endpoints
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: PF-06372865 (65mg)|DRUG: PF-06372865 (15mg)|DRUG: Pregabalin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Randomized Study to Evaluate the Safety and Efficacy of Various Doses of STP705 in Subjects With Hypertrophic Scar
Status: COMPLETED
Conditions: Hypertrophic Scar
Interventions: DRUG: STP705|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Adjuvant Gemcitabine and Capecitabine Chemotherapy in Resected Pancreatic Cancer Following Neoadjuvant Chemotherapy
Status: RECRUITING
Conditions: Pancreatic Cancer
Interventions: DRUG: Gemcitabine and Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I Study of ONO-4538HSC in Subjects With Advanced or Metastatic Solid Tumors
Status: RECRUITING
Conditions: Advanced or Metastatic Solid Tumors
Interventions: DRUG: ONO-4538HSC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety and Efficacy Study of Lepu® Drug Coated Balloon in Treatment of Coronary Small-vessel Disease
Status: UNKNOWN
Conditions: Coronary Artery Disease
Interventions: DEVICE: DCB of Lepu Medical(dimeter≥2.00 mm)|DEVICE: Restore DEB|DEVICE: DCB of Lepu Medical(dimeter<2.00 mm)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Tramadol and Oxycodone on Sleep Apnea
Status: COMPLETED
Conditions: Sleep Apnea
Interventions: DRUG: Oxycodone|DRUG: Tramadol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Investigation of SM-01 Stenting Versus PTA for the Treatment of Superficial Femoral Artery Disease
Status: COMPLETED
Conditions: Peripheral Vascular Diseases
Interventions: DEVICE: SM-01|DEVICE: PTA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Oral Versus Intravenous Ibuprofen for PDA Treatment in ELBW Infants
Status: COMPLETED
Conditions: Patent Ductus Arteriosus
Interventions: DRUG: oral ibuprofen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of Erugliflozin On Liver Fat, Liver Fibrosis and Glycemic Control in Type II DM Patients With NASH/NAFLD
Status: NOT_YET_RECRUITING
Conditions: Liver Fat|Liver Fibrosis|Glycemic Control|Body Weight Changes|Waist Circumference|Tolerance
Interventions: DRUG: Ertugliflozin 5 mg, 15mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Once Daily Metronidazole for Perforated Appendicitis
Status: WITHDRAWN
Conditions: Appendicitis
Interventions: DRUG: Metronidazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing Marginal Bone Loss for Immediately Loaded Implants in Maxillary Full Arch Interim Prosthesis Using Welded Titanium Bar Versus Polyetheretherketone Bar
Status: NOT_YET_RECRUITING
Conditions: Edentulous Jaw
Interventions: PROCEDURE: splinting dental implants with titanium bar|PROCEDURE: splinting dental implants with PEEK bar
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of Startle-response Test to Assess Transcranial Direct Current Stimulation-induced Modulation of Hyperphagia in Prader-Willi Syndrome
Status: COMPLETED
Conditions: Hyperphagia|Prader-Willi Syndrome
Interventions: DEVICE: tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Carbohydrate Count Aided by a Simulation in People With Type 1 Diabetes Mellitus. A Protocol for a Clinical Trial
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: BEHAVIORAL: STUDIA app
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of taVNS on Fibromyalgia Pain
Status: NOT_YET_RECRUITING
Conditions: Fibromyalgia, Pain
Interventions: DEVICE: Transauricular vagus nerve stimulation (taVNS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fecal Microbiome Transplant
Status: RECRUITING
Conditions: Clostridium Difficile|Inflammatory Bowel Disease|Crohn's Disease|Ulcerative Colitis
Interventions: BIOLOGICAL: Fecal Microbiota Transplant
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Electrical Vestibular Nerve Stimulation (VeNS) Compared to Sham Control as a Means of Reducing Excess Body Weight
Status: COMPLETED
Conditions: Overweight|Obesity|Overweight and Obesity|Overweight or Obesity|Metabolic Syndrome
Interventions: DEVICE: Vestal Device|DEVICE: Control Device|BEHAVIORAL: Hypocaloric Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Effectiveness of PegInterferon and Ribavirin in Korean Patients With Chronic Hepatitis C
Status: COMPLETED
Conditions: Chronic Hepatitis C
Interventions: DRUG: Peginterferon alfa-2a plus ribavirin for HCV genotype 1|DRUG: Peginterferon alfa-2a plus ribavirin for HCV genotype 2/3
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cell Therapy for Immunomodulation in Kidney Transplantation
Status: ACTIVE_NOT_RECRUITING
Conditions: Kidney Transplantation
Interventions: OTHER: Regulatory T cells|DRUG: Tocilizumab|OTHER: Bone marrow|PROCEDURE: Kidney transplant|OTHER: Immunosuppressive drug therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Efficacy and Safety of Namilumab in Participants With Chronic Pulmonary Sarcoidosis
Status: ACTIVE_NOT_RECRUITING
Conditions: Sarcoidosis, Pulmonary
Interventions: DRUG: Namilumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Non-Immersive Virtual Reality Exercises on Muscle Excitability in Knee Osteoarthritis
Status: COMPLETED
Conditions: Knee Osteoarthritis|Virtual Reality
Interventions: DEVICE: Non-immersive Virtual Reality|DEVICE: Sham Non-immersive Virtual Reality
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy in the Context of Esophageal and Gastroesophageal Junction Cancer Cachexia
Status: NOT_YET_RECRUITING
Conditions: Esophageal Adenocarcinoma
Interventions: PROCEDURE: Adipose tissue biopsies
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study Comparing Obinutuzumab and BGB-3111 Versus Obinutuzumab Alone in Treating R/R Follicular Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Relapsed/Refractory Follicular Non-Hodgkin Lymphoma
Interventions: DRUG: Zanubrutinib|DRUG: Obinutuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SPOON: Sustained Program for Improving Nutrition - Guatemala
Status: COMPLETED
Conditions: Exclusive Breast Feeding|Feeding Patterns|Stunting|Obesity, Childhood
Interventions: DIETARY_SUPPLEMENT: Micronutrient Powders|BEHAVIORAL: SPOON behavioral change strategy|DIETARY_SUPPLEMENT: SQ-LNS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Multiple Ascending Dose Trial Assessing Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ZP7570
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: ZP7570|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: To Determine Whether Galactomannan Test Will Help to Detect Fungal Infections Early and Hence Start Treatment Early
Status: COMPLETED
Conditions: Aspergillosis
Interventions: BEHAVIORAL: Galactomannan antigen monitoring, Aspergillus PCR|OTHER: blood draws|OTHER: blood draws for GM monitoring|DRUG: Amphotericin-B deoxycholate|OTHER: blood test|OTHER: Blood test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study to Evaluate the Safety of 1 New 6:2 Influenza Virus Reassortant in Adults for the 2016-2017 Season
Status: COMPLETED
Conditions: Influenza|Healthy
Interventions: BIOLOGICAL: Monovalent Influenza Vaccine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study to Explore the Effects of Probiotics on Endotoxin Levels in Type 2 Diabetes Mellitus Patients
Status: COMPLETED
Conditions: Diabetes Mellitus Type 2
Interventions: DIETARY_SUPPLEMENT: Probiotics|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Personalized Treatment for Patients With Premature Ventricular Beats
Status: RECRUITING
Conditions: Ventricular Premature Complexes
Interventions: PROCEDURE: Invasive cardiac electrophysiological study and ablation therapy|DIAGNOSTIC_TEST: Cardiopulmonary exercise testing|DIAGNOSTIC_TEST: Cardiac MRI|DIAGNOSTIC_TEST: Holter monitoring|DIAGNOSTIC_TEST: Transthoracic echocardiography|DIAGNOSTIC_TEST: Coronary angiography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical Performance Assessment of Two Silicone Hydrogel Daily Disposable Contact Lenses
Status: COMPLETED
Conditions: Refractive Errors|Myopia
Interventions: DEVICE: LID220365 contact lens|DEVICE: LID006961 contact lens
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Single Arm Feasibility Study of GlycoLeap, an On-line Lifestyle Modification and Self-management Program for People With Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: BEHAVIORAL: GlycoLeap
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study of DKN-01 in Multiple Myeloma or Advanced Solid Tumors
Status: COMPLETED
Conditions: Multiple Myeloma|Solid Tumors|Non-Small Cell Lung Cancer
Interventions: DRUG: DKN-01
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Sasanlimab in People With Non-muscle Invasive Bladder Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-muscle Invasive Bladder Cancer
Interventions: DRUG: PF-06801591|DRUG: Bacillus Calmette-Guerin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Pharmacokinetics, Safety and Tolerability of Sublingual Asenapine in a Pediatric Population With Schizophrenia or Bipolar I Disorder (P06522 AM1)
Status: COMPLETED
Conditions: Schizophrenia|Bipolar I Disorder
Interventions: DRUG: Asenapine 2.5 mg|DRUG: Asenapine 5 mg|DRUG: Asenapine 10 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Acute Lysine Administration on α-aminoadipic Acid
Status: COMPLETED
Conditions: Healthy|Pre-diabetic
Interventions: DRUG: L-Lysine|DRUG: Normal (0.9%) Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Platelet-Rich Plasma Biomembrane on Enhancing Bone Regeneration Following Endodontic Surgery
Status: COMPLETED
Conditions: Endodontic Disease
Interventions: PROCEDURE: osteotomy filled with PRP-gel and covered with PRP-biomembrane|PROCEDURE: osteotomy site following the surgical intervention was left empty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pembrolizumab With Standard Cytotoxic Chemotherapy in Treatment Naive NSCLC Patients With Asymptomatic Brain Metastases
Status: RECRUITING
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: Pemetrexed, Carboplatin, Pembrolizumab|DRUG: Paclitaxel, Carboplatin, Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long Term Study to Investigate the Efficacy & Safety of D961H (Esomeprazole) for the Prevention of NSAIDs-induced Ulcer
Status: COMPLETED
Conditions: Gastric Ulcer|Duodenal Ulcer|Rheumatoid Arthritis|Osteoarthritis|Lumbago
Interventions: DRUG: Esomeprazole 20 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: PICS: Subtitle Cardiac Dysfunction in Older Sepsis Survivors
Status: ACTIVE_NOT_RECRUITING
Conditions: Sepsis
Interventions: OTHER: Blood collection|OTHER: Urine collection|OTHER: Bioimpedance Analysis|OTHER: Cognitive Function Tests|OTHER: Quality-of-life Questionnaires|OTHER: Physical Function Tests|OTHER: Blood Collection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of SPN-812 (Viloxazine Extended-release Capsule) Low Dose in Adolescents With ADHD
Status: COMPLETED
Conditions: ADHD
Interventions: DRUG: Placebo|DRUG: 200mg SPN-812|DRUG: 400mg SPN-812
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Zoledronate and Atorvastatin in Triple Negative Breast Cancer
Status: COMPLETED
Conditions: Triple Negative Breast Cancer
Interventions: DRUG: Zoledronate|DRUG: Atorvastatin 80mg|DRUG: Standard neoadjuvant cht
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Equivalence Study of Dorzolamide 2% Eye Drops Solution
Status: COMPLETED
Conditions: Open Angle Glaucoma|Ocular Hypertension
Interventions: DRUG: Dorzolamide 2 % eye drops solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Early Amniotomy Following Transcervical Foley Balloon in the Induction of Labor
Status: ACTIVE_NOT_RECRUITING
Conditions: Labor Induction|Early Amniotomy
Interventions: PROCEDURE: Amniotomy|DEVICE: Foley balloon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Blood Pressure on Cerebral Blood Flow During Propofol Anesthesia
Status: COMPLETED
Conditions: Gastrointestinal Neoplasms|Anesthesia, General
Interventions: OTHER: MAP set at 80-85 mmHg for 5 min|OTHER: MAP set at 70-75 mmHg for 5 min|OTHER: MAP set at 60-65 mmHg for 5 min
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Motor Imagery and Action Observation on Electromyographic Activity and Intramuscular Oxygenation in the Hand Gripping Gesture
Status: COMPLETED
Conditions: Asymptomatic Subjects|Painfree Voluntiers|Neuroscience
Interventions: OTHER: Mental Practise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluating the Performance and Safety of the Medical Device Plenhyage® in the Treatment of Dermal Tissue Defects
Status: UNKNOWN
Conditions: Cicatrix|Lipodystrophy|Plaque
Interventions: DEVICE: Plenhyage
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT