pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: One Year Mortality and Morbidity With Hyperglycemia Among Acute Cerebrovascular Accident Patients in Emergency Department: A Cohort Study
Status: RECRUITING
Conditions: Cardiovascular Diseases
Interventions: OTHER: The investigators are planning to do a observational cohort study, hence won't be doing any intervention.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Assessment Of the Safety and Benefit of Prospective Immunosuppressive Drug Withdrawal in Liver Transplantation and Prediction of Operational Tolerance
Status: UNKNOWN
Conditions: Liver Transplantation
Interventions: PROCEDURE: Gradual immunosuppression drug withdrawal
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Product Use and Adaptation, Safety and Tolerability of P3P in Adult Healthy Smokers Switching to it
Status: COMPLETED
Conditions: Pharmacokinetics
Interventions: OTHER: P3P-1mg|OTHER: P3P-2mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: WEsleep Trial: Improving Sleep in Hospitalized Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Sleep|Sleep Disturbance|Sleep Hygiene|Circadian Dysrhythmia|Surgery|Sleep Disorders, Circadian Rhythm
Interventions: OTHER: WEsleep Interventions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Secondhand Effects of Hookah (i.e., Waterpipe) Smoke and Aerosol
Status: RECRUITING
Conditions: Hookah Smoking|Secondhand Aerosol|Vascular Stiffness|Vaping
Interventions: OTHER: Combustible Hookah Smoke|OTHER: Electronic Hookah Aerosol|OTHER: Clean Room Air
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Capecitabine, Oxaliplatin, Selenomethionine, and Radiation Therapy in Treating Patients Undergoing Surgery For Newly Diagnosed Stage II or III Rectal Adenocarcinoma
Status: TERMINATED
Conditions: Colorectal Cancer
Interventions: DIETARY_SUPPLEMENT: selenomethionine|DRUG: capecitabine|DRUG: oxaliplatin|OTHER: laboratory biomarker analysis|OTHER: pharmacological study|PROCEDURE: adjuvant therapy|PROCEDURE: neoadjuvant therapy|PROCEDURE: therapeutic conventional surgery|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of GastimunHp Plus in Supporting the Treatment of Peptic Ulcer Disease With Helicobacter Pylori Infection
Status: TERMINATED
Conditions: Helicobacter Pylori Infection|Peptic Ulcer
Interventions: DIETARY_SUPPLEMENT: GastimunHp Plus|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Clinical Trial Evaluating Metronomic Chemotherapy in Patients With Metastatic Osteosarcoma
Status: UNKNOWN
Conditions: Osteosarcoma
Interventions: DRUG: Cyclophosphamide|DRUG: Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Exercise Tolerance and Cardiac Output in Patients With Heart Failure After Intervention of Rehabilitation Program
Status: COMPLETED
Conditions: Heart Failure With or Without CRT-P/D
Interventions: BEHAVIORAL: Home-based cardiac rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Detection of Heterogeneity in Central Lung Cancer - EBUS-TBNA and ctDNA Analysis vs. Endobronchial Forceps Biopsy
Status: COMPLETED
Conditions: Lung Neoplasms
Interventions: PROCEDURE: EBUS-TBNA|PROCEDURE: Endobronchial forceps biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Phase 3 Study of Toripalimab Alone or in Combination With Tifcemalimab as Consolidation Therapy in Patients With Limited-stage Small Cell Lung Cancer (LS-SCLC)
Status: RECRUITING
Conditions: Limited-stage Small Cell Lung Cancer (LS-SCLC)
Interventions: DRUG: Tifcemalimab injection|DRUG: toripalimab injection|DRUG: Placebo for Tifcemalimab|DRUG: Placebo for toripalimab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PRedictive Factors and Changes From Treatment in iPCV Versus CSR Versus nAMD With afLibercept
Status: UNKNOWN
Conditions: Central Serous Chorioretinopathy|Age Related Macular Degeneration|Idiopathic Poplypoidal Choroidal Vasculopathy
Interventions: DRUG: aflibercept
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low-Dose Radiotherapy For Patients With SARS-COV-2 (COVID-19) Pneumonia
Status: ACTIVE_NOT_RECRUITING
Conditions: Covid-19|Sars-CoV2|Pneumonia
Interventions: RADIATION: Low dose radiation 35 cGy|RADIATION: High dose radiation 100 cGy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Flossing With Chlorhexidine
Status: COMPLETED
Conditions: Gingivitis
Interventions: PROCEDURE: Chlorhexidine is the generic name of the mouthwash, Peridex is the brand name.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Correlation Between Nocturnal Oxygen Desaturation and Glycemic Control in Diabetic Patients With Obstructive Sleep Apnea
Status: COMPLETED
Conditions: Obstructive Sleep Apnea|Diabetes Mellitus, Type 2
Interventions: DIAGNOSTIC_TEST: overnight pulse oximetry
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparing the Effect of Spinal Bupivacaine Versus Spinal Prilocaine on Maternal Blood Pressure in Cesarean Section
Status: NOT_YET_RECRUITING
Conditions: Spinal Anesthetics Causing Adverse Effects in Therapeutic Use
Interventions: DRUG: Bupivacaine|DRUG: Prilocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Effects of Eccentric Banded Leg Curls Versus Eccentric Cable Leg Curls Exercises in Cricket Players
Status: NOT_YET_RECRUITING
Conditions: Hamstring Muscle|Muscle Strength|Treatment Efficacy
Interventions: OTHER: eccentric cable leg curls|OTHER: eccentric banded leg curls
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Inhaled Nitric Oxide to Prevent Pulmonary Hypertension Associated to Stored Blood Transfusion
Status: WITHDRAWN
Conditions: Hypertension, Pulmonary|Hemolysis
Interventions: DRUG: Nitric Oxide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Pharmacokinetics of a Single Oral Dose of VIMOVO in Healthy Adult Volunteers
Status: COMPLETED
Conditions: Juvenile Idiopathic Arthritis
Interventions: DRUG: naproxen|DRUG: esomeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Vaccine Health Literacy Related Text Message Reminders to Increase Receipt of Second Dose of Influenza Vaccine for Young, Low Income, Urban Children
Status: COMPLETED
Conditions: Influenza
Interventions: OTHER: Text Message|OTHER: Written reminder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Efficacy and Safety Study of Fluticasone Proponate Inhalation Solution in Adult and Adolescent Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: fluticasone propionate inhalation solution|DRUG: budesonide suspension
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Campaign-based ID fIPV Administration Trial
Status: COMPLETED
Conditions: Poliomyelitis
Interventions: DEVICE: ID adaptor|DEVICE: ID Jet Injector (Tropis, Pharmajet)|DEVICE: Needle and syringe
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Safety of Dialysate Sodium Individualization in Hemodialysis Patients With Intradialytic Hypotension
Status: TERMINATED
Conditions: Hemodialysis|Hypotension
Interventions: DRUG: dialysate sodium (140 mmol/L)|DRUG: individualized dialysate sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Quit Smoking Study Using Smartphones
Status: COMPLETED
Conditions: Smoking Cessation|Smoking|Nicotine Dependence
Interventions: DRUG: Nicotine patch|BEHAVIORAL: Cessation Counseling|DEVICE: Mobile Games
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Telephone Support During Overseas Deployment for Military Spouses
Status: COMPLETED
Conditions: Military Personnel|Family Members|Resilience, Psychological|Deployment
Interventions: BEHAVIORAL: Telephone support groups|OTHER: Education webinars
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An mHealth Intervention to Improve HIV Prevention Service Engagement Among Racially Diverse Women Who Use Drugs
Status: NOT_YET_RECRUITING
Conditions: HIV Infections
Interventions: BEHAVIORAL: LOTUS mHealth Intervention Group|BEHAVIORAL: LOTUS Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of a Rehabilitation Program to Improve Quality of Life in Women Diagnosed With Endometriosis (Physio-EndEA Study)
Status: COMPLETED
Conditions: Endometriosis
Interventions: BEHAVIORAL: Lumbopelvic, stretching, aerobic and relaxation exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Assess Efficacy and Safety of RESP301 Plus Standard of Care (SOC) Compared to SOC Alone in Hospitalized Participants With COVID-19
Status: COMPLETED
Conditions: COVID-19
Interventions: DRUG: RESP301, a Nitric Oxide generating solution|OTHER: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Study of Isatuximab in Combination With Pomalidomide and Dexamethasone in MM Patients Who Received One Prior Line of Therapy Containing Lenalidomide and a Proteasome Inhibitor
Status: NOT_YET_RECRUITING
Conditions: Multiple Myeloma|Renal Impairment|Neoplasms, Plasma Cell|Neoplasms by Histologic Type|Neoplasms|Paraproteinemias|Blood Protein Disorders|Hematologic Diseases
Interventions: DRUG: Isatuximab|DRUG: Pomalidomide|DRUG: Dexamethasone|DRUG: Acetaminophen (paracetamol)|DRUG: Ranitidine (or equivalent)|DRUG: Diphenhydramine (or equivalent)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Does Ultrasound Increase the First-pass Success of Epidural Space Identification in Obese Parturients
Status: COMPLETED
Conditions: Epidural; Anesthesia
Interventions: DEVICE: Preprocedural ultrasound exam of lumbar spine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Intense Pulsed Light in the Treatment of Facial Telangiectasia in Systemic Lupus Erythematosus
Status: UNKNOWN
Conditions: Facial Telangiectasia in Patients With Systemic Lupus Erythematosus
Interventions: PROCEDURE: Intense pulsed light (IPL) treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Change in MUNIX in Patients With CMT1A Undergoing a Home Ankle Strengthening Program Versus Standard of Care
Status: COMPLETED
Conditions: Charcot-Marie-Tooth Disease
Interventions: OTHER: Home Ankle Strengthing Program|OTHER: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: The Efficacy of Adductor-Canal-Blockade on Morphine Consumption, Pain and Mobilisation After Total Knee Arthroplasty
Status: COMPLETED
Conditions: Total Knee Arthroplasty
Interventions: PROCEDURE: Adductor-Canal-Blockade|PROCEDURE: Adductor-Canal-blockade with saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Navrongo Drug Options for IPT in Pregnancy Trial
Status: COMPLETED
Conditions: Malaria
Interventions: DRUG: Sulphadoxine-pyrimethamine|DRUG: Sulphadoxine-pyrimethamine, amodiaquine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Anxiety and Depression in Epilepsy: A Treatment Study
Status: COMPLETED
Conditions: Anxiety|Depression|Epilepsy
Interventions: DRUG: Escitalopram 10mg|OTHER: Referral to Psychiatry|OTHER: Survey only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Purse String Suture for the Closure of Large Thyroidectomy Resulted in Better Cosmetics
Status: COMPLETED
Conditions: Thyroidectomy
Interventions: PROCEDURE: Purse string technique|PROCEDURE: Conventional technique
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Q8003 in the Management of Post-bunionectomy Pain
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: Q8003 (morphine sulfate and oxycodone hydrochloride)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Spironolactone for Hidradenitis Suppurativa
Status: WITHDRAWN
Conditions: Hidradenitis Suppurativa
Interventions: DRUG: Spironolactone 50 MG|DRUG: Spironolactone 100mg|DRUG: Spironolactone 200 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HEMA-free Universal Adhesives for Restoring Non-carious Cervical Lesions
Status: NOT_YET_RECRUITING
Conditions: Universal Adhesive
Interventions: OTHER: Acetone based HEMA -free universal Adhesive|OTHER: Isopropanol based HEMA- free universal Adhesive
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Patient Outcomes Reporting for Timely Assessments of Life With Depression: PORTAL-Depression
Status: COMPLETED
Conditions: Depression|Depressive Disorder, Major
Interventions: DIAGNOSTIC_TEST: CAD-MDD/CAT-DI screening via MyChart|DIAGNOSTIC_TEST: CAD-MDD/CAT-DI screening during clinic visit|OTHER: CAT-DI monitoring via MyChart|OTHER: PHQ-9 monitoring during clinic visits
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Combination of InnoSEAL Plus TR Band Compared to TR Band Alone
Status: COMPLETED
Conditions: Radial Artery Occlusion|Hematoma
Interventions: DEVICE: InnoSEAL+TRB|DEVICE: TRB alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Phase I Clinical Trial With New SARS-CoV-2 CoVacHGMix Type 5 Adenoviral Vector Vaccine
Status: UNKNOWN
Conditions: COVID-19
Interventions: BIOLOGICAL: Adeno-viral vector vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Resveratrol for the Prevention of Bone Loss in Postmenopausal Women
Status: RECRUITING
Conditions: Low Bone Mass
Interventions: DIETARY_SUPPLEMENT: Resveratrol|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effects of Iontophoresed Vasoactive Drugs on Cutaneus Blood Flow
Status: UNKNOWN
Conditions: Cardiovascular Diseases|Vascular Diseases
Interventions: DRUG: Acetylcholine|DRUG: Norepinephrine|DRUG: Phenylephrine|DRUG: Atropine|DRUG: Neostigmine|DRUG: Sterile water
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pain Control After Orthognathic Surgery
Status: UNKNOWN
Conditions: Postoperative Pain
Interventions: PROCEDURE: Trigeminal nerve block|PROCEDURE: Trigeminal nerve block|PROCEDURE: Trigeminal nerve block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Seizure Activity in Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer's Disease|Seizures
Interventions: DRUG: Low/High/Placebo Dose Keppra (Levetiracetam)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of 2-dose Vaccine Regimen Using 3 Consecutive Lots of Ad26.ZEBOV and MVA-BN-Filo in Adult Participants
Status: COMPLETED
Conditions: Ebola
Interventions: BIOLOGICAL: Ad26.ZEBOV|BIOLOGICAL: MVA-BN-Filo|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: PROstaTe Cancer - Exercise-STudy (PRO-TEST)
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: BEHAVIORAL: High Intensity Interval Training|BEHAVIORAL: Usual Care Observational Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of AZD5991 Alone or in Combination With Venetoclax in Relapsed or Refractory Haematologic Malignancies.
Status: TERMINATED
Conditions: Relapsed or Refractory Acute Myeloid Leukemia (AML)
Interventions: DRUG: AZD5991|DRUG: AZD5991 + Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long Acting LHRH Versus Short Acting LHRH in the Treatment of Prostate Cancer
Status: UNKNOWN
Conditions: Prostate Cancer
Interventions: DRUG: luteinizing hormone-releasing hormone (LHRH) short acting or long acting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Soy Modulation of Immune Activation, LDL- Levels, and Lowering Inflammation by Pretzel Isoflavone Dietary Intervention
Status: TERMINATED
Conditions: Human Immunodeficiency Virus (HIV) Infection|Hypercholesterolemia
Interventions: DIETARY_SUPPLEMENT: Soy Pretzel|OTHER: Wheat Pretzel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Carbon Dioxide Insufflation (CO2) and Warm Water Infusion (WWI) Versus Standard Air Insufflation (AI) for Unsedated Colonoscopy
Status: COMPLETED
Conditions: Warm Water|CO2 Colonoscopy|Unsedated Colonoscopy
Interventions: PROCEDURE: CO2|PROCEDURE: Warm water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: Levothyroxine for Non-Alcoholic Fatty Liver Disease (NAFLD)
Status: TERMINATED
Conditions: Non-Alcoholic Fatty Liver Disease|Diabetes Mellitus, Type 2
Interventions: DRUG: Levothyroxine Sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Study of Oral Atogepant Versus Oral Topiramate to Assess Adverse Events in Adult Participants With Migraine
Status: RECRUITING
Conditions: Migraine
Interventions: DRUG: Atogepant|DRUG: Placebo for Atogepant|DRUG: Topiramate|DRUG: Placebo for Topiramate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Histaminergic Basis of Fatigue in Multiple Sclerosis
Status: WITHDRAWN
Conditions: Multiple Sclerosis
Interventions: DRUG: L-Histidine|DRUG: Placebo|DRUG: Lodosyn
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Three Way Interaction Between Gabapentin, Duloxetine, and Donepezil in Patients With Diabetic Neuropathy
Status: TERMINATED
Conditions: Diabetic Neuropathic Pain|Chronic Low Back Pain
Interventions: DRUG: donepezil|DRUG: duloxetine|DRUG: donepezil 2.5 mg and duloxetine 30mg|DRUG: placebo|DRUG: gabapentin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dinutuximab, Sargramostim, and Combination Chemotherapy in Treating Patients With Newly Diagnosed High-Risk Neuroblastoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Ganglioneuroblastoma|High Risk Neuroblastoma
Interventions: PROCEDURE: Autologous Hematopoietic Stem Cell Transplantation|DRUG: Carboplatin|DRUG: Cisplatin|DRUG: Cyclophosphamide|DRUG: Dexrazoxane|BIOLOGICAL: Dinutuximab|DRUG: Doxorubicin|DRUG: Etoposide|RADIATION: External Beam Radiation Therapy|DRUG: Isotretinoin|DRUG: Melphalan|BIOLOGICAL: Sargramostim|DRUG: Thiotepa|DRUG: Topotecan|DRUG: Vincristine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Safety, Tolerability and Pharmacokinetics of Increasing Repeated Oral Doses of Ambroxol Lozenges in Healthy Male Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Ambroxol - in single rising doses|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effect of a Psychological Program for Children With Autism Spectrum Disorder and Feeding Difficulties
Status: RECRUITING
Conditions: Autism Spectrum Disorder
Interventions: BEHAVIORAL: TEAlimento : a multicomponent parent training behavioral program to treat feeding difficulties in children with Autism Spectrum Disorder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nilotinib 300 mg BID in Newly Diagnosed CP-CML Patients to Verify Disappearance of CD34+/Lin-Ph+ Cells
Status: COMPLETED
Conditions: Leukemia, Myeloid, Chronic-Phase
Interventions: DRUG: Nilotinib 300mg BID
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: L-Gastrectomy With the Intelligent Navigation 4K UHD 3D Endoscopic Imaging System
Status: UNKNOWN
Conditions: Stomach Neoplasms
Interventions: DEVICE: Laparoscopic gastrectomy with Intelligent Navigation 4K UHD 3D Endoscopic Imaging System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 1, First-in-human Study of Oral TP-1287 in Patients With Advanced Solid Tumors
Status: TERMINATED
Conditions: Advanced Solid Tumors|Sarcoma|Ewing Sarcoma|Dedifferentiated Liposarcoma|Synovial Sarcoma
Interventions: DRUG: TP-1287
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a New Anti-cancer Immunotherapy After Chemotherapy in Adult Patients With Acute Myeloid Leukemia (AML)
Status: COMPLETED
Conditions: Leukaemia, Myelocytic, Acute
Interventions: BIOLOGICAL: GSK Biologicals' recombinant WT1 Antigen-Specific Cancer Immunotherapeutic (ASCI)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Measurement of Cerebral rSO2 Levels During Sleep in Children With Suspected Obstructive Sleep Apnea
Status: UNKNOWN
Conditions: Obstructive Sleep Apnea|Pediatric Sleep Apnea
Interventions: DIAGNOSTIC_TEST: INVOS
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: An Investigational Drug for the Prevention of Chemotherapy-Induced Nausea and Vomiting (MK-0869-071)
Status: COMPLETED
Conditions: Nausea|Vomiting|Breast Neoplasms
Interventions: DRUG: MK0869, aprepitant / Duration of Treatment: 3 days|DRUG: Comparator: ondansetron / Duration of Treatment: 3 days
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Efficacy and Safety of VX-765 in Subjects With Treatment-Resistant Partial Epilepsy
Status: TERMINATED
Conditions: Epilepsy
Interventions: DRUG: VX-765 Part A|DRUG: Placebo|DRUG: VX-765 Part B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Immunogenicity and Safety of the Booster Doses of a Live-attenuated Mumps Vaccine in Junior High School Students
Status: ACTIVE_NOT_RECRUITING
Conditions: Mumps|Influenza
Interventions: BIOLOGICAL: Mumps vaccine, Live (MV)|BIOLOGICAL: Influenza Vaccine, inactivated, quadrivlent(QIV)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study to Assess the Tolerability and the Safety of the Transition From Inhaled Treprostinil to Oral Selexipag in Patients With Pulmonary Arterial Hypertension
Status: COMPLETED
Conditions: Pulmonary Arterial Hypertension
Interventions: DRUG: Selexipag
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tell Me More ("Dime Mas")
Status: RECRUITING
Conditions: HIV|Mental Health Issue
Interventions: BEHAVIORAL: Tell Me More ("Dime Mas")|BEHAVIORAL: Peer Ambassador Stories [Listen Miami ("Oye Miami")]|BEHAVIORAL: Standard Community Outreach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Transcranial Direct Current Stimulation in Offenders
Status: COMPLETED
Conditions: Aggression|Risk-Taking|Antisocial Behavior
Interventions: DEVICE: Transcranial direct current stimulation|DEVICE: Sham transcranial direct current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Nitric Oxide-mediated Cardioprotection During Cardiac Surgery With Cardiopulmonary Bypass
Status: COMPLETED
Conditions: Coronary Artery Disease|Coronary Artery Bypass|Cardiopulmonary Bypass|Nitric Oxide|Reperfusion Injury, Myocardial
Interventions: DRUG: Nitric Oxide|OTHER: Standard CPB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Role of Brain Dopamine in Chronic Pain
Status: RECRUITING
Conditions: Chronic Pain
Interventions: DRUG: Methylphenidate|DRUG: carbidopa-levodopa|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Basket Trial of an ERK1/2 Inhibitor (LY3214996) in Combination With Abemaciclib.
Status: TERMINATED
Conditions: Cancer|Cancer Metastatic|BRAF V600E|MEK1 Gene Mutation|MEK2 Gene Mutation|ERK Mutation|RAF1 Gene Mutation
Interventions: DRUG: Abemaciclib|DRUG: LY3214996
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Peri-articular Injection Utilizing a Pain Cocktail With and Without Exparel
Status: WITHDRAWN
Conditions: Total Knee Arthroplasty|Pain Management
Interventions: DRUG: Cocktail|DRUG: Exparel|DRUG: Marcaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Confirming The Sitaxsentan Dose In Patients Undergoing Heart Surgery
Status: COMPLETED
Conditions: Cardiac Surgery Subjects|Subjects Undergoing CABG and/or Cardiac Valve Replacement
Interventions: DRUG: sitaxsentan (Thelin)|DRUG: sitaxsentan (Thelin)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Safety and Pharmacokinetics of Single Doses of VBY-376 in Healthy Adults
Status: COMPLETED
Conditions: Chronic Hepatitis C Infection
Interventions: DRUG: VBY 376
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose:
Clinical trial: A Comparison of Protein-bound and Large Molecular Weight Uremic Toxin Removals With Novel Super High-flux Dialyzer Between Hemodialysis and High Volume Online HDF Modalities
Status: COMPLETED
Conditions: Uremic; Toxemia
Interventions: DEVICE: ELISIO21HX
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High-dose FOLFIRI in Advanced Colorectal Cancer Patients With Wild-type UGT1A1*6 and *28
Status: UNKNOWN
Conditions: Colorectal Cancer
Interventions: DRUG: Irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of AEG33773 Versus Placebo in Patients With Painful Diabetic Peripheral Neuropathy
Status: COMPLETED
Conditions: Diabetic Peripheral Neuropathy|Chronic Pain
Interventions: DRUG: AEG33773 oral dosing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PROtein, Leucine and Vitamin D Supplementation In Patients With GYnecologic Cancer Receiving Platinum-based Chemotherapy
Status: NOT_YET_RECRUITING
Conditions: Gynecologic Cancer
Interventions: DIETARY_SUPPLEMENT: Experimental product - Fortifit® Powder|OTHER: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intraoperative Warming During Major Surgical Procedures Using the Esophageal Temperature Management System
Status: TERMINATED
Conditions: Hypothermia Following Anesthesia|Hypothermia|Surgery
Interventions: DEVICE: EnsoETM|DEVICE: Surface Warming
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Combined Endoscopic & Radiologic Intervention For Management Of Acute Perforated Peptic Ulcer
Status: COMPLETED
Conditions: Abdomen, Acute
Interventions: PROCEDURE: combined endoscopic & radiologic intervention for management of acute perforated peptic ulcer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Sorafenib and Transarterial Chemoembolization (TACE) to Treat Hepatocellular Carcinoma
Status: COMPLETED
Conditions: Hepatocellular Carcinoma|Hepatoma
Interventions: DRUG: sorafenib|PROCEDURE: LC Bead-TACE
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study of Irinotecan in Patients With Breast Cancer and CNS Metastases
Status: WITHDRAWN
Conditions: Central Nervous System Metastases|Male Breast Cancer|Recurrent Breast Cancer|Stage IV Breast Cancer
Interventions: DRUG: irinotecan hydrochloride|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of the Effect of Output on New Adhesives
Status: COMPLETED
Conditions: Ileostomy - Stoma
Interventions: OTHER: Standard hydrocolloid adhesive patch|OTHER: LT-2|OTHER: LT-21|OTHER: 33-20
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluate Mesothelin as a Biomarker for the Clinical Management of Esophageal Adenocarcinoma (EAC)
Status: ACTIVE_NOT_RECRUITING
Conditions: Esophageal Cancer|Adenocarcinoma
Interventions: OTHER: serum and tissue mesothelin|OTHER: serum and tissue mesothelin|OTHER: serum and tissue mesothelin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Lapatinib Ditosylate in Treating Patients With Metastatic or Recurrent Head and Neck Cancer
Status: COMPLETED
Conditions: Recurrent Salivary Gland Cancer|Recurrent Squamous Cell Carcinoma of the Hypopharynx|Recurrent Squamous Cell Carcinoma of the Larynx|Recurrent Squamous Cell Carcinoma of the Lip and Oral Cavity|Recurrent Squamous Cell Carcinoma of the Nasopharynx|Recurrent Squamous Cell Carcinoma of the Oropharynx|Recurrent Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity|Recurrent Verrucous Carcinoma of the Larynx|Recurrent Verrucous Carcinoma of the Oral Cavity|Salivary Gland Squamous Cell Carcinoma|Stage IV Squamous Cell Carcinoma of the Hypopharynx|Stage IV Squamous Cell Carcinoma of the Nasopharynx|Stage IVA Salivary Gland Cancer|Stage IVA Squamous Cell Carcinoma of the Larynx|Stage IVA Squamous Cell Carcinoma of the Lip and Oral Cavity|Stage IVA Squamous Cell Carcinoma of the Oropharynx|Stage IVA Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity|Stage IVA Verrucous Carcinoma of the Larynx|Stage IVA Verrucous Carcinoma of the Oral Cavity|Stage IVB Salivary Gland Cancer|Stage IVB Squamous Cell Carcinoma of the Larynx|Stage IVB Squamous Cell Carcinoma of the Lip and Oral Cavity|Stage IVB Squamous Cell Carcinoma of the Oropharynx|Stage IVB Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity|Stage IVB Verrucous Carcinoma of the Larynx|Stage IVB Verrucous Carcinoma of the Oral Cavity|Stage IVC Salivary Gland Cancer|Stage IVC Squamous Cell Carcinoma of the Larynx|Stage IVC Squamous Cell Carcinoma of the Lip and Oral Cavity|Stage IVC Squamous Cell Carcinoma of the Oropharynx|Stage IVC Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity|Stage IVC Verrucous Carcinoma of the Larynx|Stage IVC Verrucous Carcinoma of the Oral Cavity|Tongue Cancer
Interventions: DRUG: lapatinib ditosylate|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare Pharmacokinetics and Pharmacodynamics of RinGlar® to Lantus® in Type 1 Diabetes Mellitus Patients
Status: COMPLETED
Conditions: Clamp Study
Interventions: DRUG: RinGlar®|DRUG: Lantus®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Pre-exercise Carbohydrate Restriction Relative to Fasting on Metabolism, Appetite, and Energy Intake in Healthy Males.
Status: COMPLETED
Conditions: Obesity|Metabolic Syndrome
Interventions: BEHAVIORAL: Low-Carbohydrate Pre-Exercise Meal|BEHAVIORAL: High-Carbohydrate Pre-Exercise Meal|BEHAVIORAL: Fasted Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Bioequivalence Studies of Dasatinib 100 mg
Status: NOT_YET_RECRUITING
Conditions: Myeloma Multiple
Interventions: DRUG: Dasatinib 100 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Gemcitabine and Docetaxel in Treating Patients With Recurrent Osteosarcoma (Closed to Accrual as of 12/21/06) or Ewing's Sarcoma or Unresectable or Locally Recurrent Chondrosarcoma
Status: COMPLETED
Conditions: Sarcoma
Interventions: BIOLOGICAL: filgrastim|BIOLOGICAL: pegfilgrastim|DRUG: docetaxel|DRUG: gemcitabine hydrochloride|GENETIC: microarray analysis|OTHER: laboratory biomarker analysis|OTHER: pharmacokinetic study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endoscopic Submucosal Resection Turbinoplasty VS Turbinectomy
Status: COMPLETED
Conditions: Turbinate; Hypertrophy Mucous Membrane
Interventions: PROCEDURE: Submucosal Resection Turbinoplasty Versus Partial Inferior Turbinectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Infra- and Ultrasound on the Brain
Status: COMPLETED
Conditions: Brain Function|Ultrasound|Cognitive Function|Well-being|Depression|Sleep
Interventions: DEVICE: Infrasound (85 dB; 6Hz) source|DEVICE: Ultrasound (10dB below hearing threshold; 22.4 kHz) source|DEVICE: Infrasound dummy source|DEVICE: Ultrasound dummy source
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Safety of IDP-124 Lotion for the Treatment of Moderate to Severe Atopic Dermatitis in Pediatric and Adult Subjects
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: IDP-124 Lotion|DRUG: IDP-124 Vehicle Lotion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mesenchymal Stem Cells in Osteonecrosis of the Femoral Head
Status: COMPLETED
Conditions: Avascular Necrosis of Femur Head
Interventions: BIOLOGICAL: XCEL-MT-OSTEO-ALPHA|PROCEDURE: Standard treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hydrocortisone Treatment for Symmetric Lipomatosis Associated With Neuropathy (SLN): an N-of-1 Study Hydrocortisone Treatment for Symmetric Lipomatosis Associated With Neuropathy (SLN): an N-of-1 Study
Status: UNKNOWN
Conditions: Symmetric Lipomatoses, Multiple
Interventions: DRUG: Hydrocortisone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PRP Versus PRF Versus Conventional Treatment in Chronic Non-healing Skin Ulcers
Status: RECRUITING
Conditions: Chronic Non-healing Skin Ulcers
Interventions: OTHER: platelet-rich plasma|OTHER: platelet-rich fibrin|OTHER: Surgical debridement, normal saline washing and dressing coverage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating Pyrroloquinoline Quinone (PQQ) for Improving Obese Pregnancy Outcomes
Status: NOT_YET_RECRUITING
Conditions: Maternal Obesity
Interventions: DRUG: Pyrroloquinoline quinone (PQQ)|DRUG: Placebo with soybean oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Prospective Open-label Comparison of Two Vitamin D3 Repletion Strategies in Vitamin D Deficient Patients
Status: COMPLETED
Conditions: Vitamin D 25 OH Deficiency
Interventions: DIETARY_SUPPLEMENT: Cholecalciferol|DIETARY_SUPPLEMENT: Cholecalciferol 5,000 IU
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Legal-Education Plus Trauma-informed Therapy to Improve Community Acceptance and Reintegration of Repentant Terrorists in Nigeria
Status: UNKNOWN
Conditions: Trauma, Psychological|Legal Education
Interventions: BEHAVIORAL: Legal Education plus Trauma-informed Therapy (LETiT)|BEHAVIORAL: Intervention As Usual (IAU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Metabolic Phenotyping and Follow-Up of Patients With and Without Diabetes After New Onset of STEMI
Status: RECRUITING
Conditions: ST-segment Elevation Myocardial Infarction (STEMI)|Diabetes Mellitus|Insulin Resistance|Non-Alcoholic Fatty Liver Disease
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Bi-Weekly Docetaxel Plus 24-Hour Infusion of High-Dose 5-Fluorouracil / Leucovorin (HDFL) for Inoperable Advanced or Metastatic Gastric Cancer
Status: TERMINATED
Conditions: Gastric Cancer
Interventions: DRUG: Taxteral|DRUG: 5-Fluorouracil|DRUG: Leucovorin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EffectiveNess of Low-dose Aspirin in Prevention of Cancer in the Stomach and Oesophagus (GastrointEstinal Cancer Prevention) - United Kingdom ("ENgAGE - UK"): Study to Evaluate the Risk of Cancer in the Stomach and Oesophagus Among New Users of Low-dose Aspirin Using the THIN Database in the UK
Status: COMPLETED
Conditions: Prevention of Oesophagus Cancer and Stomach Cancer
Interventions: DRUG: Acetylsalicylic Acid(BAYE4465, Aspirin )
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Trial for Patients With Advanced/Recurrent Cervical Cancer
Status: COMPLETED
Conditions: Cervical Intraepithelial Neoplasia|Uterine Neoplasms|Genital Neoplasms, Female
Interventions: DRUG: Pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multi-domain Versus Uni-Domain Training on Executive Control and Memory Functions of Older Adults
Status: UNKNOWN
Conditions: Executive Functions|Memory Functions
Interventions: BEHAVIORAL: Cognitive training|BEHAVIORAL: Physical training|BEHAVIORAL: Cognitive control|BEHAVIORAL: Physical control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Tc99m-MAA Bronchial Artery Injection During Bronchial Embolization for Pulmonary Mass Induced Hemoptysis for Dosimetry Planning
Status: RECRUITING
Conditions: Lung Cancer
Interventions: BIOLOGICAL: Tc99m-MAA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Addition of Probiotic Consumption to a Nutritional Intervention and Caloric Restriction on Body Weight and Composition in Overweight Participants
Status: COMPLETED
Conditions: Obesity
Interventions: OTHER: Weight loss|DRUG: Probiotic Formula|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the National Tool for Observation of Infection Prevention Measures in the Healthcare (NOST)
Status: NOT_YET_RECRUITING
Conditions: Infections, Respiratory|Healthcare Worker Patient Transmission
Interventions: BEHAVIORAL: NOST
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Phase II Trial of COL-3 in Patients With HIV Related Kaposi's Sarcoma
Status: TERMINATED
Conditions: AIDS-related Kaposi Sarcoma|HIV Infection
Interventions: DRUG: incyclinide|DRUG: incyclinide|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 2, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of up to Two Doses of Psilocybin for the Treatment of Major Depressive Disorder in Adults With Cancer
Status: RECRUITING
Conditions: Cancer|Major Depressive Disorder
Interventions: DRUG: Psilocybin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Care Partner-Assisted Diabetes Self-Management Through Linking Continuous Glucose Monitoring With Mobile Health: Improving Outcomes for Older Adults With Mild Cognitive Impairment
Status: RECRUITING
Conditions: Type 2 Diabetes|Mild Cognitive Impairment
Interventions: DEVICE: Continuous Glucose Monitor (CGM)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of Emotional Freedom Technique on Perceived Stress and General Self-Efficacy in Nursing Students
Status: COMPLETED
Conditions: Emotion Regulation|Stress|Self Efficacy
Interventions: OTHER: Emotional Freedom Technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE