pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Combination Herbal Therapy (CHT) Versus Placebo in Patients With Irritable Bowel Syndrome (IBS)
Status: COMPLETED
Conditions: Colonic Diseases, Functional
Interventions: DRUG: CHT - herbal therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: PARTNER II Trial: Placement of AoRTic TraNscathetER Valves II - High Risk and Nested Registry 7
Status: COMPLETED
Conditions: Symptomatic Severe Aortic Stenosis
Interventions: DEVICE: TAVR Implantation of the THV Prosthesis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hematopoietic Cell Transplantation for Patients With Hematologic Malignancies Using Related, HLA-Haploidentical Donors
Status: RECRUITING
Conditions: Hematologic Neoplasms
Interventions: DRUG: Cyclophosphamide|OTHER: Hematopoietic Stem Cell Transplantation,
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparison of 122-0551 Foam Versus Vehicle Foam in Subjects With Plaque Psoriasis (Study 310)
Status: COMPLETED
Conditions: Plaque Psoriasis
Interventions: DRUG: 122-0551 Foam|DRUG: Vehicle Foam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combined Effects of Virtual Reality and Motor Imagery Techniques With Routine Physical Therapy in Post Stroke Patients
Status: RECRUITING
Conditions: Stroke
Interventions: OTHER: Virtual Reality technique + Motor Imagery technique + Routine Physical Therapy|OTHER: Virtual Reality + Routine Physical Therapy|OTHER: Motor Imagery +Routine Physical Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Various Aerobic Exercises on Abdominal Obesity in Women With Metabolic Syndrome.
Status: COMPLETED
Conditions: Metabolic Syndrome
Interventions: OTHER: Supervised treadmill group (%70 VO2 max) (group 1)|OTHER: Supervised treadmill group (%50 VO2 max) (group 2)|DEVICE: ECE PEDO pedometer group (%50 VO2 max) (group 3)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: COvid-19 and Vitamin D Supplementation: a Multicenter Randomized Controlled Trial of High Dose Versus Standard Dose Vitamin D3 in High-risk COVID-19 Patients (CoVitTrial)
Status: COMPLETED
Conditions: Coronavirus
Interventions: DRUG: cholecalciferol 200,000 IU|DRUG: cholecalciferol 50,000 IU
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tailored Hydration for the Prevention of Post-ERCP Pancreatitis
Status: COMPLETED
Conditions: Cholangiopancreatography, Endoscopic Retrograde|Pancreatitis
Interventions: DRUG: Tailored aggressive hydration|DRUG: Tailored standard hydration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Bowel Preparation Impact on the Intestinal Microbiome: Oral Preparation vs Enema
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: OTHER: Oral-agents/Enema
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pulmonary Rehabilitation in Non-chronic Obstructive Pulmonary Disease Patients.
Status: NOT_YET_RECRUITING
Conditions: Pneumonia|Pulmonary Fibrosis|Tuberculosis|Bronchiectasis|Asthma
Interventions: OTHER: Conventional Chest Physiotherapy|OTHER: Aerobic training Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of Diacylglycerol Oil on Risk Factors of Type 2 Diabetes and Complicating Disease, and Mechanism
Status: COMPLETED
Conditions: Insulin Sensitivity|Type 2 Diabetes|Cardiovascular Disease
Interventions: DIETARY_SUPPLEMENT: diacylglycerol oil|DIETARY_SUPPLEMENT: triacylglycerol oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Reduction of Plasma Free VEGF-A Using Low-dose Bevacizumab in Hemodialysis Patients
Status: WITHDRAWN
Conditions: End Stage Renal Disease|Hemodialysis Vascular Access Failure
Interventions: DRUG: 1.25mg bevacizumab|DRUG: 2.50mg bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: SMART Study: A Study of Re-treatment With MabThera (Rituximab) in Patients With Rheumatoid Arthritis Who Have Failed on Anti-TNF Alfa Therapy
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Study of E6005 in Patients With Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: E6005|DRUG: E6005 ointment (vehicle)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Efficacy and Safety of Brensocatib in Participants With Chronic Rhinosinusitis Without Nasal Polyps (CRSsNP)
Status: RECRUITING
Conditions: Chronic Rhinosinusitis Without Nasal Polyps
Interventions: DRUG: Brensocatib|DRUG: Placebo|DRUG: Mometasone furoate nasal spray (MFNS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Premixed vs Basal Bolus Insulin Therapy in Older Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes Treated With Insulin
Interventions: DRUG: premixed insulin therapy|DRUG: basal bolus insulin therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Follow-up Study of Chondrogen® Delivered by Intra-Articular Injection Following Meniscectomy
Status: COMPLETED
Conditions: Recovery Following Partial Medial Meniscectomy
Interventions: DRUG: Chondrogen|DRUG: Chondrogen|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PrEveNtion of Biliary Events After Acute Pancreatitis In NonSUrgicaL pAtients: PENINSULA Trial
Status: NOT_YET_RECRUITING
Conditions: Acute Pancreatitis Due to Gallstones|Acute Pancreatitis
Interventions: PROCEDURE: Biliary sphincterotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Emergency Department Digital Pain Self-Management Intervention to Improve Acute Low Back Pain Outcomes
Status: RECRUITING
Conditions: Low Back Pain, Mechanical|Acute Pain
Interventions: BEHAVIORAL: Emergency Department Digital Pain Self-Management Intervention (EDPSI)|OTHER: Routine Discharge Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Quality of Labour Epidural Analgesia With Intrathecal Morphine as a Component of Combined Spinal Epidural: a Double-blinded Randomized Control Trial
Status: NOT_YET_RECRUITING
Conditions: Labor Pain
Interventions: DRUG: Intrathecal morphine|OTHER: Saline solution (placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Role of Oral Tramadol 50 mg in Reducing Pain During Colposcopy-directed Cervical Biopsy
Status: UNKNOWN
Conditions: Cervical Biopsy
Interventions: DRUG: an oral tramadol 50 mg(Tramal, Memphis, Giza, Egypt) tablet|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effects of Sodium and Potassium on Blood Pressure, Vascular Function and Renal Function
Status: COMPLETED
Conditions: Hypertension|Blood Pressure|Vascular Function|Renal Function
Interventions: DIETARY_SUPPLEMENT: Sodium|DRUG: Potassium|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of the Efficacy and Safety of Immunoadsorption and Intravenous Immunoglobulin for Guillain-Barre Syndrome
Status: NOT_YET_RECRUITING
Conditions: Guillain-Barre Syndrome
Interventions: DEVICE: immunosorbent column|DRUG: intravenous immunoglobulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dose Escalation Trial of BIBW 2992 Administration in Combination With Docetaxel in Patients With Advanced Solid Tumors
Status: COMPLETED
Conditions: Neoplasms
Interventions: DRUG: BIBW 2992|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Head Yuanshi Dian Therapy in Burning Mouth Syndrome
Status: UNKNOWN
Conditions: Burning Mouth Syndrome|Oral Mucosa Disease
Interventions: DRUG: oryzanol + vitamin B2 (riboflavin) + vitamin E
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of a Pre-Workout on Performance, Perceptual Responses, Energy Feelings and Muscular Properties, After a Training Microcycle in Adults.
Status: COMPLETED
Conditions: Protein Deficiency|Training Group, Sensitivity|Fatigue|Muscular Atrophy|Psychological
Interventions: DIETARY_SUPPLEMENT: Pre-Workout Supplement|OTHER: Resistance Training|OTHER: Endurance Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Hilotherm Therapy on Post-operative Pain and Swelling Following Surgical Wisdom Tooth Removal
Status: UNKNOWN
Conditions: Molar, Third|Wisdom Teeth
Interventions: DEVICE: Hilotherm cooling face mask
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Placebo and Active Controlled Study of ONO-6950 in Asthmatic Patients
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: ONO-6950|DRUG: ONO-6950|DRUG: Montelukast|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Metabolic Differences of an Oral and Intravenous Dose of 3-hydroxybutyrate (3-OHB).
Status: COMPLETED
Conditions: Healthy|Incretin Effect|Ketosis
Interventions: DIETARY_SUPPLEMENT: 3-OHB salt (NaCl)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect of Administering a Small Dose of Glucose During Cesarean Section
Status: UNKNOWN
Conditions: Cesarean Section
Interventions: DRUG: administer acetate Ringer's solution|DRUG: acetate Ringer's solution containing no glucose|DRUG: acetate Ringer's solution containing 1% glucose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Optimization of Mycoplasm Pneumonia Antibiotic Therapy
Status: COMPLETED
Conditions: Mycoplasma Pneumonia
Interventions: DRUG: Moxifloxacin|DRUG: Cephalosporins and azithromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Sound-Insulated Music Playing and Fıgured Mask Nebulızer Application on the Processing Anxiety of Children
Status: COMPLETED
Conditions: Anxiety|Child, Only
Interventions: DEVICE: using a soundproof nebulizer with a music and a funny mask added|DEVICE: using a silent nebulizer with no extra attachments|DEVICE: using a routinely employed nebulizer
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of Intermittent Oral Dosing of ASP1517 in Erythropoieses Stimulating Agent (ESA)-Naive Hemodialysis Chronic Kidney Disease Patients With Anemia
Status: COMPLETED
Conditions: ESA-naive Hemodialysis Chronic Kidney Disease Patients With Anemia
Interventions: DRUG: roxadustat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Medical Versus Surgical Management of Moderate Mitral Regurgitation Following Percutaneous Coronary Intervention
Status: WITHDRAWN
Conditions: Myocardial Infarction|Mitral Regurgitation
Interventions: PROCEDURE: surgical mitral valve repair w/ mitral valve annuloplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Premature Rupture of Membranes With a Bishop Score<6: Comparison of Medical Induction/Expectant Management
Status: COMPLETED
Conditions: Medical Induction of Labor Affecting Newborn
Interventions: DRUG: Oxytocin|DRUG: Dinoprostone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Removal of Animal Milk From the Diet in Functional Dyspepsia: A Cross-sectional Study
Status: COMPLETED
Conditions: Dyspepsia|Gastrointestinal System Disease
Interventions: OTHER: removing milk and dairy products from diets without medical treatment|OTHER: According to current standard algorithms and guidelines, appropriate treatment for FD types.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of Long Coronary Artery Stents With Third-generation Dual-source Computed Tomography Angiography
Status: COMPLETED
Conditions: Coronary Artery Disease|Chronic Total Occlusion of Coronary Artery
Interventions: DIAGNOSTIC_TEST: Coronary computed tomography angiography|DIAGNOSTIC_TEST: Invasive coronary angiography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Benefits of a Cannabidiolic Acid Topical Cream for the Treatment of Restless Leg Syndrome
Status: ACTIVE_NOT_RECRUITING
Conditions: Restless Legs Syndrome
Interventions: DRUG: Chylobinoid Topical Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HAIC Combined Sintilimab for Liver Metastasis From Esophageal Squamous Cell Carcinoma
Status: COMPLETED
Conditions: Hepatic Arterial Infusion Chemotherapy|Liver Metastases|Esophageal Squamous Cell Carcinoma
Interventions: DRUG: HAIC combined with intravenous PD-1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Open-Label Crossover Bioavailability Study of Celecoxib in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: celecoxib reference formulation|DRUG: celecoxib test formulation A1|DRUG: celecoxib test formulation B2|DRUG: celecoxib test formulation C1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Toripalimab Combined With CAV/IE Regimen
Status: RECRUITING
Conditions: Soft Tissue Sarcoma
Interventions: DRUG: Toripalimab Combined With CAV/IE chemotherapy|DRUG: CAV/IE alternate chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mechanical Insufflation-exsufflation and Hypertonic Saline in Nosocomial Bacterial Respiratory Tract Infection
Status: NOT_YET_RECRUITING
Conditions: Nosocomial Infection|Nosocomial Pneumonia|Tracheobronchitis|Mechanical Ventilation Complication|Endotracheal Intubation
Interventions: DEVICE: Mechanical insufflation-exsufflation|OTHER: Standard of Care|OTHER: Hypertonic saline with hyaluronic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Hematological Malignancy With Novel CAR-T Cells.
Status: UNKNOWN
Conditions: B-cell Non Hodgkin Lymphoma|B-cell Acute Lymphoblastic Leukemia|Multiple Myeloma
Interventions: BIOLOGICAL: Novel CAR-T
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Connecting Alaska Native People to Quit Smoking
Status: COMPLETED
Conditions: Tobacco Use|Tobacco Smoking|Tobacco Use Cessation|Smoking Cessation|Smoking, Cigarette|Smoking, Tobacco|Smoking
Interventions: BEHAVIORAL: Facebook Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preoperative Use of Alprazolam and Hydroxyzine in Anxiety
Status: UNKNOWN
Conditions: Agitation on Recovery From Sedation
Interventions: DRUG: Hydroxyzine Hydrochloride|DRUG: Alprazolam tablet|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: DEPLIPIDO Study: Functional and Lipidomic Analysis of Plasma HDL in Patients With Depression Compared to Controls
Status: RECRUITING
Conditions: Depression
Interventions: OTHER: HDRS-17 depression scale|BIOLOGICAL: Blood sampling
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Dacomitinib (PF-00299804) As A Single Oral Agent In Selected Patients With Adenocarcinoma Of The Lung
Status: COMPLETED
Conditions: Carcinoma, Non-small Cell
Interventions: DRUG: Dacomitinib (PF-00299804)|DRUG: Dacomitinib (PF-00299804)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Electrical Impedance Imaging of Patients on Mechanical Ventilation
Status: COMPLETED
Conditions: Pneumothorax|Pulmonary Contusion|Pleural Effusion|Pulmonary Edema|Atelectasis|Hyperinflation|Emphysema|Acute Respiratory Distress Syndrome
Interventions: DEVICE: Mechanical Ventilation|DEVICE: CT Scan
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Doxorubicin Hydrochloride, Pembrolizumab, Vinblastine, and Dacarbazine in Treating Patients With Classical Hodgkin Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Classical Hodgkin Lymphoma
Interventions: DRUG: Dacarbazine|DRUG: Doxorubicin Hydrochloride|OTHER: Laboratory Biomarker Analysis|BIOLOGICAL: Pembrolizumab|DRUG: Vinblastine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Extension to a Study to Assess the Efficacy and Safety of Three Doses of Vildagliptin in Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: vildagliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Radiofrequency Ablation for Barrett Oesophagus With Low Grade Dysplasia
Status: COMPLETED
Conditions: Barrett Oesophagus|Low Grade Dysplasia
Interventions: PROCEDURE: Endoscopic radiofrequency ablation|OTHER: Endoscopic surveillance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stereotactic Radiation Therapy and Combination Chemotherapy in Treating Patients Undergoing Surgery for Locally Advanced Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DRUG: gemcitabine hydrochloride|DRUG: oxaliplatin|PROCEDURE: adjuvant therapy|PROCEDURE: neoadjuvant therapy|RADIATION: hypofractionated radiation therapy|RADIATION: stereotactic radiosurgery
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Two Different Botulinum Toxin Type A Treatments for Moderate to Severe Cervical Dystonia
Status: TERMINATED
Conditions: Spasmodic Torticollis
Interventions: BIOLOGICAL: botulinum toxin type A|BIOLOGICAL: botulinum toxin type A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Activity of TroVax® Versus Placebo in Relapsed Asymptomatic Ovarian Cancer
Status: COMPLETED
Conditions: Ovarian Cancer|Fallopian Tube Cancer|Peritoneal Cancer
Interventions: BIOLOGICAL: TroVax®|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Acitretin Plus Pioglitazone in Patients With Psoriasis
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: Pioglitazone|DRUG: Acitretin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: VIsualization of Coronary Artery Disease for Modification of RISK Factors
Status: RECRUITING
Conditions: Coronary Artery Disease|Non-Obstructive Coronary Atherosclerosis
Interventions: OTHER: Follow up at GP|OTHER: Consultation|OTHER: Visualization of CTA images
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Follow-up Study to Assess a Second Boost Immunization With AFFITOPE® PD01A With Regard to Safety and Clinical Activity (AFF008AA)
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: BIOLOGICAL: AFFITOPE® PD01A
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Immunogenicity and Safety of an Investigational Influenza Vaccine (H1N1) in Adults
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: GSK investigational vaccine GSK2340272A|BIOLOGICAL: GSK investigational vaccine GSK2340269A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Safety and Antiretroviral Activity of MK-0518 Versus Efavirenz in Treatment Naive HIV-Infected Patients, Each in Combination With TRUVADA (0518-021 EXT)
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: MK-0518|DRUG: Comparator: efavirenz|DRUG: Comparator: Truvada|DRUG: Comparator: Placebo to MK-0518|DRUG: Comparator: Placebo to efavirenz
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Opioid Growth Factor in Treating Patients With Advanced Pancreatic Cancer That Cannot Be Removed By Surgery
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: BIOLOGICAL: opioid growth factor|BIOLOGICAL: metenkephalin, OGF-opioid growth factor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Botulinum Toxin Type A (AGN-151607) for the Prevention of Post-operative Atrial Fibrillation in Adult Participants Undergoing Open-chest Cardiac Surgery (NOVA)
Status: COMPLETED
Conditions: Post-Operative Atrial Fibrillation
Interventions: DRUG: AGN-151607|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study to Evaluate the Safety and Efficacy of 5-ALA-SFC in Type II Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: 5-ALA-SFC|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Strategy Game Supporting Goal Management Training Intervention
Status: COMPLETED
Conditions: Acquired Brain Injury|Executive Dysfunction|Neuropsychological Rehabilitation
Interventions: BEHAVIORAL: Game-Supported Goal Management Training|BEHAVIORAL: Information Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nutritional Support in Patients With Nutritional Risk. How we Can Improved the Prognosis and Quality of Life
Status: TERMINATED
Conditions: Malnutrition|Quality of Life
Interventions: DIETARY_SUPPLEMENT: Food dish|DIAGNOSTIC_TEST: Indirect calorimetric|DIAGNOSTIC_TEST: Bioimpedance|BEHAVIORAL: Questioners|DIETARY_SUPPLEMENT: Plated food dish
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of Belimumab in Black Race Patients With Systemic Lupus Erythematosus (SLE)
Status: COMPLETED
Conditions: Systemic Lupus Erythematosus
Interventions: BIOLOGICAL: Placebo plus standard therapy|BIOLOGICAL: Belimumab 10 mg/kg plus standard therapy|DRUG: Standard therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Single and Multiple-Dose Study of Aramchol in Healthy Male Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Aramchol|DRUG: Aramchol|DRUG: Aramchol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SynRinse Irrigation Pilot (SIP) Trial
Status: COMPLETED
Conditions: Sinusitis, Chronic|Cystic Fibrosis With Other Manifestations
Interventions: DRUG: Synrinse
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cerebral Perfusion Pressure (CPP) Management Information Feedback and Nursing
Status: COMPLETED
Conditions: Traumatic Brain Injury|Subarachnoid Hemorrhage
Interventions: OTHER: Bedside display of cerebral perfusion pressure information
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasound-enhanced Uptake of Chemotherapy in Patients With Inoperable Pancreatic Ductal Adenocarcinoma
Status: COMPLETED
Conditions: Carcinoma, Pancreatic Ductal
Interventions: COMBINATION_PRODUCT: SonoVue|DRUG: Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective Study of Patients Treated for Bone and Joint Infection (BJI) Due to Staphylococcus Aureus, Aiming at Identifying Biomarkers of Diagnosis Interest in Chronic BJI
Status: TERMINATED
Conditions: Bone and Join Infection (BJI)|Periprosthetic Joint Infection (PJI)
Interventions: OTHER: Constitution of serum bank at D0|OTHER: Constitution of serum bank during follow-up|OTHER: ELISA assays of serum markers of bone remodeling at D0|OTHER: ELISA assays of serum markers of bone remodeling during follow-up|OTHER: Analysis of bacterial gene expression at D0
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: TeleHealth Resources for IndiVidualizEd Goals (THRIVE) in Alcohol Recovery Study
Status: RECRUITING
Conditions: Alcohol Use Disorder|Alcohol Drinking|Alcohol-Related Disorders
Interventions: BEHAVIORAL: Mindfulness-based relapse prevention|BEHAVIORAL: Online Mutual Support Groups
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Peritoneal Damage in Laparoscopic Surgery
Status: COMPLETED
Conditions: Peritoneal Damage
Interventions: PROCEDURE: Low pressure pneumoperitoneum|PROCEDURE: standard pneumoperitoneum pressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Ondansetron Versus Aprepitant Plus Ondansetron for Emesis
Status: COMPLETED
Conditions: Hematologic Diseases|Acute Myelogenous Leukemia|Myelodysplastic Syndrome|Chronic Myelogenous Leukemia
Interventions: DRUG: Ondansetron|DRUG: Aprepitant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Probiotics in HIV-1 Infection
Status: COMPLETED
Conditions: HIV-1 Infection
Interventions: DIETARY_SUPPLEMENT: Multi-strain probiotic|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: COVID-19 Study Assessing the Virologic Efficacy of REGN10933+REGN10987 Across Different Dose Regimens in Adult Outpatients With SARS-CoV-2 Infection
Status: COMPLETED
Conditions: COVID-19
Interventions: DRUG: REGN10933+REGN10987 combination therapy|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I Trial of Measles Vectored Chikungungya Vaccine
Status: COMPLETED
Conditions: Chikungunya Virus Infection
Interventions: OTHER: Placebo|BIOLOGICAL: VRC-CHKVLP059-00-VP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Adding TTPB to SAPB in Breast Cancer Surgery
Status: RECRUITING
Conditions: Acute Pain|Opioid Use
Interventions: PROCEDURE: Transversus thoracis plane block combined with serratus anterior plane block|PROCEDURE: Serratus anterior plan block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: GlutN : Randomized, Double-blind, Crossover Clinical Trial to Confirm the Role of Gluten in Non-celiac Gluten Sensitivity
Status: TERMINATED
Conditions: The Objective is to Confirm the Role of Gluten in Triggering the Digestive and Extradigestive Symptoms of NCGS
Interventions: DIETARY_SUPPLEMENT: Clinical study comparing a gluten-containing diet to a gluten-free diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Brain-heart Interactions in Tako-Tsubo Cardiomyopathy and Cardiac Syndrome X:
Status: COMPLETED
Conditions: Takotsubo Cardiomyopathy|Cardiac X Syndrome|Acute Myocardial Infarction
Interventions: OTHER: Manual for the Assessment and Documentation of Psychopathology (AMDP 8)|OTHER: Million Clinical Multiaxial Inventory 3 (MCMI-III)|OTHER: State-Trait Anxiety Inventory form Y (STAI-Y)|OTHER: SF-36 Health-Related Quality of Life|OTHER: Blood oxygenation level dependent- functional Magnetic Resonance Imaging (BOLD-fMRI)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Comparative Study of Postprocessing Imaging Systems for Diminutive Colonic Polyps
Status: COMPLETED
Conditions: Diminutive Colon Polyp|Adenomatous Polyp|Hyperplastic Polyp|Colonoscopy
Interventions: OTHER: Observation using NBI system|OTHER: Observation using i-Scan system
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Spinal Cord Stimulation (SCS) for Neuropathic Pain of Back or Lower Extremity
Status: TERMINATED
Conditions: Intractable Neuropathic Pain|Pain|Back Pain|Lower Extremity Pain
Interventions: DEVICE: Precision for Spinal Cord Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cognition and Emotion in Meditation: A Comparison Between Mindfulness and Compassion Standardized Programs
Status: COMPLETED
Conditions: Well-being|Emotion Regulation|Cognitive Control|Attention|Psychological Distress|Psychophysiologic Reaction|Compassion|Mindfulness
Interventions: BEHAVIORAL: Mindfulness-Based Stress Reduction|BEHAVIORAL: Compassion Cultivation Training|OTHER: Control Group
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Compassion and Attention Longitudinal Meditation Study
Status: COMPLETED
Conditions: Immune System Processes|Inflammatory Activation and Modulation|ANS Function
Interventions: BEHAVIORAL: Cognitive-Based Compassion Training|BEHAVIORAL: Mindful Attention Training|BEHAVIORAL: Adult Health Education Curriculum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effectiveness of Mulligan Mobilization Technique and Core Stabilization Exercise With Knee Osteoarthritis
Status: COMPLETED
Conditions: Exercise
Interventions: OTHER: Mulligan mobilization|OTHER: Core stabilization|OTHER: Conventional therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Study Estimates the Longitudinal Impact of a Gamified Health Education App on Students' Health and Learning Outcomes
Status: ENROLLING_BY_INVITATION
Conditions: Infectious Disease|COVID-19|Physical Inactivity|Health Behavior|Nutrition, Healthy|Habit, Diet
Interventions: BEHAVIORAL: FYA-003
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Effect of Sodium Reduction on Blood Pressure and Physical Function in Older Adults
Status: COMPLETED
Conditions: Hypertension|Physical Disability|Aging
Interventions: OTHER: Dietary intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of PD-1/CTLA-4 Bispecific AK104 in Relapsed or Refractory Peripheral T-cell Lymphoma
Status: TERMINATED
Conditions: Peripheral T-cell Lymphoma
Interventions: BIOLOGICAL: AK104
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study in Healthy Men to Test How Itraconazole Influences the Amount of BI 1323495 in the Blood
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BI 1323495|DRUG: Itraconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Exercise and 5-HTP on Cortisol Levels
Status: UNKNOWN
Conditions: Plasma Cortisol
Interventions: DIETARY_SUPPLEMENT: 5-HTP|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Early Molecular Changes in Vitiligo After Narrowband Ultraviolet Therapy
Status: COMPLETED
Conditions: Vitiligo|Dermatology/Skin - Other
Interventions: DEVICE: Phototherapy (NB-UVB) via the 3 Series PC & SP phototherapy cabinet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Non-psychoactive Cannabidiol as an Adjunct to Botulinum Toxin in Blepharospasm
Status: COMPLETED
Conditions: Blepharospasm|Blepharospasm, Benign Essential|CBD
Interventions: DRUG: Cannabidiol Oral Solution [Epidiolex]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Intracardiac Echocardiography or Left Atrial Appendage Radiography to Guide Implantation of a Left Atrial Appendage Occlusion Device
Status: RECRUITING
Conditions: Left Atrial Appendage Occlusion
Interventions: DEVICE: intracardiac echocardiography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of Protein Supplement on Vertebral Fusion in Posterior Spine Fusion Surgery
Status: COMPLETED
Conditions: Spine Surgery
Interventions: DRUG: protein supplement|OTHER: Carbo Mass
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Smokeless Tobacco Cessation Intervention for Firefighters
Status: COMPLETED
Conditions: Smokeless Tobacco Cessation
Interventions: BEHAVIORAL: #EnufSnuff.TXT- First Responder|BEHAVIORAL: Enough Snuff Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial of a Botanical Drug Containing East Indian Sandalwood Oil (EISO) for Treatment of Common Warts
Status: COMPLETED
Conditions: Common Warts
Interventions: DRUG: 10% EISO|DRUG: Placebo|DRUG: 20% EISO|DRUG: 30% EISO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Safety and Efficay Investigation of CAR-T Cell Therapy for Patients With Hematological Malignancies
Status: RECRUITING
Conditions: Acute Lymphoblastic Leukemia|Lymphoma|Multiple Myeloma
Interventions: BIOLOGICAL: CAR-T Autologous T cell injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Pharmacokinetics of Multiple Ascending Doses of NIO752 in Progressive Supranuclear Palsy
Status: ACTIVE_NOT_RECRUITING
Conditions: Progressive Supranuclear Palsy (PSP)
Interventions: DRUG: antisense oligonucleotide|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial Evaluating the Diagnostic Usefulness of Lumentin® 44 When Used as Contrast Agent
Status: COMPLETED
Conditions: Crohn Disease
Interventions: DIAGNOSTIC_TEST: Lumentin|DIAGNOSTIC_TEST: Movprep
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Continuing Somatostatin Analogues Upon Progression in Neuroendocrine Tumour pAtients
Status: RECRUITING
Conditions: Gastroenteropancreatic Neuroendocrine Tumor
Interventions: DRUG: Somatostatin analog
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Brimonidine 0.1% Versus Brinzolamide 1% as Adjunctive Therapy to Latanoprost 0.005%
Status: COMPLETED
Conditions: Glaucoma|Ocular Hypertension
Interventions: DRUG: latanoprost 0.005% eye drops and brimonidine 0.1% eye drops|DRUG: latanoprost 0.005% eye drops and brinzolamide 1.0% eye drops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Extracellular Vesicles From Mesenchymal Cells in the Treatment of Acute Respiratory Failure
Status: NOT_YET_RECRUITING
Conditions: Severe Acute Respiratory Syndrome (SARS)|Acute Respiratory Distress Syndrome (ARDS)|Pneumonia
Interventions: BIOLOGICAL: intravenous treatment with EVs|BIOLOGICAL: intravenous treatment with placebo solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Fabrication of a Definitive Cad/Cam Titanium Abutment Prior to Guided Surgery: a Pilot Study.
Status: COMPLETED
Conditions: Single Edentulous Space
Interventions: DEVICE: abutment margin 0.5 mm subgingival|DEVICE: abutment margin 1.5 mm subgingival
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: ADAPT Transcatheter Aortic Valve Intervention (TAVI & Chronic Total Occlusion Percutaneous Coronary Intervention (CTO PCI)
Status: UNKNOWN
Conditions: Transcatheter Aortic Valve Replacement|Percutaneous Coronary Intervention
Interventions: DIAGNOSTIC_TEST: activated partial thrombin time
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Objective Evaluation of Paclitaxel/Docetaxel-induced Neuropathy in Breast Cancer Patients
Status: COMPLETED
Conditions: Breast Cancer|Chemotherapy Induced Peripheral Neuropathy|Paclitaxel Induced Neuropathy
Interventions: DIAGNOSTIC_TEST: Quantitative measures of reduction in Chemotherapy Induced Neuropathy (CIPN) and Cognitive Impairment (CICI) in patients with stage I-III breast cancer
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical and Radiographic of the Effect of Socket Preservation Using the Roll Pedicle Connective Tissue Graft With Bovine Bone: A Case Series Trial.
Status: COMPLETED
Conditions: Socket Preservation
Interventions: PROCEDURE: roll pedicle connective tissue graft with bovine bone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pegliposomal Doxorubicin and 5-fluorouracil as Second Line Therapy for Metastatic Gastric Cancer
Status: UNKNOWN
Conditions: Gastric Cancer
Interventions: DRUG: Irinotecan|DRUG: DOXOrubicin Liposome Injection|DRUG: 5fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 2b Study to Evaluate Rezpegaldesleukin (Rezpeg) in the Treatment of Adult Patients With Moderate-to-Severe Atopic Dermatitis
Status: RECRUITING
Conditions: Moderate to Severe Atopic Dermatitis
Interventions: DRUG: Rezpegaldesleukin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Uremic Toxin Absorbent (AST-120) to Treat Hospital Acquired Acute Kidney Injury
Status: UNKNOWN
Conditions: Acute Kidney Injury
Interventions: DRUG: AST-120and pentoxyphylline (PTX)|DRUG: pentoxyphylline (PTX)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial Evaluating Efficacy and Safety of Dasiglucagon in Children With Congenital Hyperinsulinism
Status: COMPLETED
Conditions: Congenital Hyperinsulinism
Interventions: DRUG: dasiglucagon|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Biweekly TPF Induction Chemotherapy for Locally Advanced Squamous Cell Carcinoma of Head and Neck
Status: COMPLETED
Conditions: Locally Advanced Head and Neck Carcinoma
Interventions: DRUG: docetaxel, cisplatin, fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Ginger on the Incidence of Postoperative Nausea and Vomiting
Status: COMPLETED
Conditions: Postoperative Nausea and Vomiting
Interventions: DIETARY_SUPPLEMENT: Ginger|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of 90Y-DOTA-hLL2 as a Consolidation Therapy After R-CHOP in Patients With Diffuse Large B-cell Lymphoma
Status: TERMINATED
Conditions: B-cell Lymphoma
Interventions: DRUG: 90Y-DOTA-hLL2
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: LEMURS SSI: Evaluation of Behavioral Incentives
Status: RECRUITING
Conditions: Incentives
Interventions: BEHAVIORAL: Personal Incentives|BEHAVIORAL: Personal Restorative Incentives|BEHAVIORAL: Charity Incentives|BEHAVIORAL: Charity Restorative Incentives
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Shedding Study of Adenovirus Serotype 26 Based Respiratory Syncytial Virus Pre-fusion F Protein (Ad26.RSV.preF) Vaccine in Adults
Status: COMPLETED
Conditions: Healthy
Interventions: BIOLOGICAL: Ad26.RSV.preF
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Interdisciplinary Study of A Novel Anticonvulsant in Alcoholism
Status: COMPLETED
Conditions: Alcohol Dependence
Interventions: DRUG: Zonisamide|BEHAVIORAL: Take Control|DRUG: Placebo (for Zonisamide)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Influence of Food-intake on Desmopressin Oral Tablets and MELT-formulation
Status: COMPLETED
Conditions: Enuresis|Polyuria
Interventions: DRUG: desmopressin tablet|DRUG: desmopressin MELT formulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT