pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Phase 1 Clinical Trial of AUR106 in Patients With Relapsed Advanced Malignancies
Status: RECRUITING
Conditions: Relapse|Advanced Malignant Neoplasm|Non Small Cell Lung Cancer|Gastric Cancer|Urothelial Carcinoma|Kidney Cancer|Colon Cancer|Esophagus Cancer
Interventions: DRUG: AUR106
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Human Amniotic Membrane Grafting and Standard of Care Versus Standard of Care Alone in the Treatment of Venous Leg Ulcers
Status: COMPLETED
Conditions: Venous Leg Ulcer
Interventions: OTHER: EpiFix|OTHER: Compression Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Qualitative and Quantitative Evaluation of Vascular Flows of Radial, Ulnar and Interdigital Arterial Trees Under Normal and Pathological Conditions by 3 Tesla MRI
Status: RECRUITING
Conditions: Magnetic Resonance Imaging|Vascular Complications|Transplantation|Radial Artery
Interventions: OTHER: MRI acquisitions|OTHER: Doppler ultrasound procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Single Ascending Dose Study of BMS-650032 in HCV Infected Subjects
Status: COMPLETED
Conditions: Chronic Hepatitis C
Interventions: DRUG: BMS-650032 or Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Adrenomedullin Upregulation in Apical Periodontitis
Status: COMPLETED
Conditions: Periapical Periodontitis
Interventions: DIAGNOSTIC_TEST: Apical periodontitis|DIAGNOSTIC_TEST: Chronic periodontitis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Home Based Care Transitions Tailored by Cognition and Patient Activation
Status: COMPLETED
Conditions: Chronic Disease
Interventions: BEHAVIORAL: Grp 1 Low Cognition, Low Activation|BEHAVIORAL: Grp 2 Low Cognition, High Activation|BEHAVIORAL: Grp 3 Normal Cognition, Low Activation|BEHAVIORAL: Grp 4 Normal Cognition, High Activation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 1, First-In-Human Study of Escalating Doses of Oral TVB-2640 in Patients With Solid Tumors
Status: COMPLETED
Conditions: Solid Malignant Tumor
Interventions: DRUG: TVB-2640
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 3 Adjuvated Reduced Dose IPV-Al SSI Vaccines and Non-adjuvated Full Dose IPV SSI, as Booster Vaccination to Adolescents
Status: COMPLETED
Conditions: Immunization, Booster
Interventions: BIOLOGICAL: 1/3 IPV-Al SSI, manufactured by SSI, Denmark|BIOLOGICAL: 1/5 IPV-Al SSI, manufactured by SSI, Denmark|BIOLOGICAL: 1/10 IPV-Al SSI, manufactured by SSI, Denmark|BIOLOGICAL: IPV SSI, manufactured by SSI, Denmark
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Phase II Clinical Trial of NIVO-IPI-TAXANE in Untreated Metastatic NSCLC
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: Nivolumab|DRUG: Ipilimumab|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of Rituximab in Subjects With International Society of Nephrology/Renal Pathology Society (ISN/RPS) 2003 Class III or IV Lupus Nephritis
Status: COMPLETED
Conditions: Lupus Nephritis
Interventions: DRUG: Rituximab|DRUG: Placebo|DRUG: Mycophenolate mofetil|DRUG: Methylprednisolone|DRUG: Diphenhydramine|DRUG: Acetaminophen|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of MPC-7869 to Treat Patients With Alzheimer's
Status: COMPLETED
Conditions: Alzheimer Disease|Dementia
Interventions: DRUG: MPC-7869|DRUG: MPC-7869
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Sleep Apnea in Asthmatic Children and Teenagers
Status: COMPLETED
Conditions: Asthma, Bronchial|Bronchial Asthma|Apnea, Sleep|Sleep Apnea, Mixed Central and Obstructive|Sleep Hypopnea (Diagnosis)|Obstructive Sleep Apnea|Obstructive Sleep Apnea Syndrome
Interventions: OTHER: Questionnaire|OTHER: Lung Function Test|OTHER: Home Sleep Study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Lidocaine And Neuromonitoring in Thyroid Surgery
Status: COMPLETED
Conditions: Thyroid Neoplasm|Parathyroid Neoplasms|Anesthesia
Interventions: DRUG: Intravenous lidocaine|DRUG: Intravenous placebo|PROCEDURE: Intra-cuff lidocaine|PROCEDURE: Intra-cuff placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Determine Whether 2 Investigational Malaria Vaccines Are Safe, Protective Against Malaria in Adults
Status: COMPLETED
Conditions: Malaria
Interventions: BIOLOGICAL: Group A FMP2.1/AS01B|BIOLOGICAL: Group B FMP2.1/AS02A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Olive Oil's Cream Effectiveness in Prevention of Pressure Ulcers in Immobilized Patients in Primary Care
Status: UNKNOWN
Conditions: Pressure Ulcer
Interventions: DRUG: Hyper-oxigenated fatty acid|OTHER: Olive oil's cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The HeartWare™ Ventricular Assist System as Destination Therapy of Advanced Heart Failure: the ENDURANCE Trial
Status: COMPLETED
Conditions: Chronic Heart Failure
Interventions: DEVICE: HeartWare® VAS|DEVICE: Control LVAD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Different Dialysis Strategies on Inflammation in COVID-19 Maintenance Hemodialysis Patients
Status: COMPLETED
Conditions: Covid19|Hemodialysis Complication|Inflammatory Response
Interventions: PROCEDURE: Expanded Hemodialysis for Covid19 maintenance hemodialysis patients|PROCEDURE: Hemodialysis by protein-leaking dialyzer for Covid19 maintenance hemodialysis patients
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Individualized Hemodynamic Optimization by Indirect Measurement of the Respiratory Quotient in Major Surgery: Prospective Randomized Multicentre Open-Label Study (OPHIQUE) Individualized Optimization by Indirect Measurement of the Respiratory Quotient
Status: COMPLETED
Conditions: Post-Op Complication|Respiratory Complication
Interventions: PROCEDURE: : hemodynamic management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Clinical Study to Investigate if a Single Dose of an Approved Drug Product (Glycopyrrolate Inhalation Solution) Reduces Trapped Air in the Lungs of Participants With Chronic Obstructive Pulmonary Disease.
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: COMBINATION_PRODUCT: Glyocopyrrolate Inhalation Solution administered by Magnair|DRUG: Placebo administered by Magnair
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Sleep Disordered Breathing and Cardiopulmonary Disease in Peruvian Highlanders
Status: COMPLETED
Conditions: Sleep Disordered Breathing|Sleep Apnea
Interventions: DEVICE: Inclined Sleep
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ganglionated Plexi Ablation Combined With Pulmonary Vein Isolation
Status: COMPLETED
Conditions: Persistent Atrial Fibrillation
Interventions: PROCEDURE: Pulmonary vein isolation|PROCEDURE: Ganglionated plexi ablation|PROCEDURE: Linear Lesion Ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetically-driven Dosing of Mycophenolate Mofetil for the Treatment of Pediatric Proliferative Lupus Nephritis
Status: WITHDRAWN
Conditions: Lupus Nephritis
Interventions: DRUG: Mycophenolate Mofetil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Pharmacokinetics Study of DWC20155 and DWC20156 in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Co-administration of DWC20155 and DWC20156|DRUG: DWJ1366 Tab.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Supplemental Hydrogen Plus PQQ for Mitochondrial Biomarkers and Brain Function in Elderly With Mild Cognitive Impairment
Status: RECRUITING
Conditions: Age-associated Memory Impairment
Interventions: DIETARY_SUPPLEMENT: Supplement|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Clinical Evaluation of Tunneled Coronally Advanced Flap v.s Coronally Advanced Flap With Graft for Gingival Recession
Status: RECRUITING
Conditions: Gingival Recession, Localized
Interventions: PROCEDURE: Tunneled coronal advanced flap with connective tissue graft|PROCEDURE: Coronally advanced flap with connective tissue graft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Open-Label Study to Assess the Pharmacokinetics and Safety of HALAVEN in Subjects With Cancer Who Also Have Impaired Renal Function
Status: COMPLETED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: E7389|DRUG: E7389|DRUG: E7389
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II, Open Label, Non-randomized, Trial of BKM120 for Metastatic or Locally Advanced Cervical Cancer
Status: WITHDRAWN
Conditions: Treatment for Metastatic or Locally Advanced Cervical Cancer
Interventions: DRUG: BKM120
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Safety and Effectiveness of Lyophilized Certolizumab Pegol in the Treatment of Signs and Symptoms of Rheumatoid Arthritis and in Prevention of Joint Damage in Patients With Active Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: BIOLOGICAL: Certolizumab Pegol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neurofeedback for Tourette Syndrome
Status: COMPLETED
Conditions: Tourette Syndrome|Chronic Tic Disorder
Interventions: PROCEDURE: Neurofeedback|PROCEDURE: Sham feedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessing Safety & Efficacy of MediTate Temporary Implant in Subjects With Benign Prostate Hyperplasia
Status: COMPLETED
Conditions: Bladder Neck Obstruction|Benign Prostate Hyperplasia
Interventions: DEVICE: Insertion of Temporary Implantable Nitinol Device (TIND)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Imaging With a New Agent That Finds a Cancer Protein Called HER2
Status: COMPLETED
Conditions: HER2-positive Carcinoma|HER2-positive Primary Malignancy
Interventions: DRUG: Zr-DFO-pertuzumab PET/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Personalized Approach to Abdominal Pain in Irritable Bowel Syndrome
Status: RECRUITING
Conditions: Irritable Bowel Syndrome|Inflammatory Bowel Diseases|Crohn Disease|Ulcerative Colitis|Functional Gastrointestinal Disorders|Lifestyle Factors
Interventions: DEVICE: ESM and Traqq
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Open Labeled RCT on the Effect of Additional hCG Injection for LPS on Pregnancy Outcomes in IHH Patients
Status: RECRUITING
Conditions: Luteal Phase Deficiency|Luteal Phase Support|Idiopathic Hypogonadotropic Hypogonadism
Interventions: DRUG: Additional hCG injection|DRUG: estrogen and dydrogesterone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigation of the Efficacy of Treatments With Backup Device in Spine Pathologies
Status: COMPLETED
Conditions: Spine Disease|Neck Pain|Back Pain|Disc Herniation
Interventions: OTHER: conventional physiotherapy|OTHER: Backup therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Biomarkers in DNA Samples From Patients With Acute Lymphoblastic Leukemia or Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Adult Acute Myeloid Leukemia With Inv(16)(p13.1q22); CBFB-MYH11|Adult Acute Myeloid Leukemia With t(8;21); (q22; q22.1); RUNX1-RUNX1T1|Adult Acute Promyelocytic Leukemia With PML-RARA|Childhood Acute Lymphoblastic Leukemia in Remission|Childhood Acute Myeloid Leukemia|Childhood Acute Myeloid Leukemia in Remission|Recurrent Childhood Acute Lymphoblastic Leukemia|Recurrent Childhood Acute Myeloid Leukemia|Secondary Acute Myeloid Leukemia
Interventions: OTHER: Laboratory Biomarker Analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase 1 Dose Escalation Study of TAK-901 in Subjects With Advanced Hematologic Malignancies
Status: COMPLETED
Conditions: Acute Myeloid Leukemia|Acute Lymphoblastic Leukemia|Chronic Myelogenous Leukemia|Chronic Lymphocytic Leukemia|Multiple Myeloma|Waldenstrom's Macroglobulinemia|Myelodysplastic Syndrome|Philadelphia Chromosome-negative CML|Myeloid Metaplasia|Myelofibrosis|Advanced Polycythemia|Non-Hodgkins Lymphoma
Interventions: DRUG: TAK-901
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact vs. Dienogest: A Combined Oral Contraceptive in the Size of Endometriomas
Status: SUSPENDED
Conditions: Endometriosis
Interventions: DRUG: Dienogest|DRUG: Levonorgestrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Fit for Two: Incorporating Wearable Trackers Into Clinical Care for Pregnant Women With Diabetes (FFT)
Status: COMPLETED
Conditions: Physical Activity|Type 2 Diabetes Mellitus
Interventions: BEHAVIORAL: physical activity counseling & Fitbit
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Severe LH Suppressed Patients After Administration of a GnRH Antagonist
Status: COMPLETED
Conditions: Infertility, Female Infertility, Male Infertility
Interventions: DRUG: Recombinant LH (Luveris)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Safety, Tolerability, Pharmacokinetic/Pharmacodynamic Characteristics and Food Effect of HGR4113 in Healthy Subjects
Status: RECRUITING
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: HGR4113|DRUG: Placebo|DRUG: HGR4113|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Unstructured Eye Tracking as a Diagnostic and Prognostic Biomarker in Parkinsonian Disorders
Status: RECRUITING
Conditions: Parkinson's Disease and Parkinsonism|Progressive Supranuclear Palsy|Multiple System Atrophy|Corticobasal Degeneration
Interventions: BEHAVIORAL: Free-viewing eye tracking
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study Evaluating Bemarituzumab in Combination With Other Anti-cancer Therapies in Subjects With Previously Untreated Advanced Gastric or Gastroesophageal Junction Cancer.
Status: RECRUITING
Conditions: Gastric Cancer|Gastroesophageal Junction Cancer
Interventions: DRUG: Bemarituzumab|DRUG: CAPOX|DRUG: SOX|DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Optimal Albuterol Regimens for Acute Asthma Exacerbations: DBRCT Pilot Study
Status: COMPLETED
Conditions: Acute Asthma
Interventions: DRUG: Albuterol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Using TENS to Relieve Pain and Potentiate the Rehabilitation of Pain Patients
Status: WITHDRAWN
Conditions: Chronic Pain
Interventions: DEVICE: Active transcutaneous electrical nerve stimulation (TENS)|DEVICE: Simulated transcutaneous electrical nerve stimulation (TENS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transcranial Direct Current Stimulation as a Neuroprotection in Acute Stroke Before and After Thrombectomy
Status: TERMINATED
Conditions: Acute Ischemic Stroke
Interventions: DEVICE: Transcranial Direct Current Stimulation (tDCS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Autogenous Grafts for Anterior Maxillary Horizontal Ridge Augmentation
Status: COMPLETED
Conditions: Alveolar Ridge Augmentation
Interventions: PROCEDURE: Horizontal ridge augmentation by symphyseal bone block placed and fixed buccally as onlay graft|PROCEDURE: Horizontal ridge augmentation by symphyseal bone block interpositioned in space created between buccal and lingual cortex as inlay graft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness and Safety of Treatment of Insulin Glargine in Type 2 Diabetes Mellitus Following Glucagon-like Peptide-1 (GLP-1) Failure
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: INSULIN GLARGINE HOE 901
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Everolimus With Multiagent Re-Induction Chemotherapy in Pediatric Patients With ALL
Status: COMPLETED
Conditions: Acute Lymphoblastic Leukemia
Interventions: DRUG: Everolimus|DRUG: Prednisone|DRUG: Vincristine|DRUG: PEG-Asparaginase|DRUG: Doxorubicin|DRUG: Dexrazoxane
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating System Accuracy and User Performance of Omnitest® Blood Glucose Monitoring Systems for Self-testing in Managing Diabetes Mellitus
Status: TERMINATED
Conditions: Diabetes
Interventions: DEVICE: Blood glucose monitoring system (Omnitest 3)|DEVICE: Blood glucose monitoring system (Omnitest 5)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Behavioral Trial Studying Programmed Training to Improve Advocacy Skills for Individuals With Traumatic Brain Injury
Status: COMPLETED
Conditions: Brain Injuries
Interventions: BEHAVIORAL: Advocacy training curriculum|BEHAVIORAL: Self-directed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: The Chronic Effects of Carnitine on Recovery
Status: COMPLETED
Conditions: Muscle Soreness|Muscle Damage|Resistance Training|Oxidative Stress|Muscle Strength
Interventions: DIETARY_SUPPLEMENT: Carnipure|OTHER: Resistance Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Clinical Outcomes in an Online Teledermatology Model for the Management of Psoriasis
Status: COMPLETED
Conditions: Psoriasis
Interventions: OTHER: Online Teledermatology Care|OTHER: Conventional in Office Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Bortezomib in Treating Patients With Malignant Pleural Mesothelioma
Status: COMPLETED
Conditions: Malignant Mesothelioma
Interventions: DRUG: bortezomib|PROCEDURE: quality-of-life assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Communication Training to Involve Older People in Decisions to DEPRESCRIBE Cardiometabolic Medication: a Cluster-randomized Trial in Primary Care
Status: ENROLLING_BY_INVITATION
Conditions: Deprescriptions|Polypharmacy|Primary Health Care|Community Pharmacy Services|Decision Making, Shared
Interventions: OTHER: communication training programme for healthcare providers
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study of IMC-11F8 in Patients With Tumors Who Have Not Responded to Standard Therapy
Status: COMPLETED
Conditions: Solid Tumors
Interventions: BIOLOGICAL: IMC-11F8|BIOLOGICAL: IMC-11F8|BIOLOGICAL: IMC-11F8|BIOLOGICAL: IMC-11F8 I.V.|BIOLOGICAL: IMC-11F8|BIOLOGICAL: IMC-11F8|BIOLOGICAL: IMC-11F8|BIOLOGICAL: IMC-11F8|BIOLOGICAL: IMC-11F8|BIOLOGICAL: IMC-11F8|BIOLOGICAL: IMC-11F8|BIOLOGICAL: IMC-11F8
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Safety, Tolerability, and Exploratory Efficacy of Adjunctive EQU-001 for Seizures in Adults With Epilepsy
Status: ACTIVE_NOT_RECRUITING
Conditions: Epilepsy
Interventions: DRUG: Placebo|DRUG: EQU-001
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Molecular Analysis of Thrombocytopenia and Cancer (MATAC): Investigating Antigenic Mimicry Between Platelets and Tumor Cells in Patients With Immune Thrombocytopenia (ITP) Associated With Cancer
Status: NOT_YET_RECRUITING
Conditions: Immune Thrombocytopenia|Immune Thrombocytopenic Purpura|Neoplasms|Cancer
Interventions: OTHER: ITP and cancer
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pharmacological Countermeasures for High Altitude
Status: ACTIVE_NOT_RECRUITING
Conditions: Hypobaric Hypoxia
Interventions: DRUG: Acetazolamide|DRUG: Erythropoietin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Surufatinib and Envafolimab as Second or More-line Therapy in Advanced Soft Tissue Sarcoma Patients
Status: NOT_YET_RECRUITING
Conditions: Efficacy and Safety of Surufatinib Combined With Envafolimab as Second or More-line Therapy in Advanced Soft Tissue Sarcoma Patients
Interventions: DRUG: Surufatinib + envafolimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Topotecan in Patients With Refractory Acute Leukemia
Status: COMPLETED
Conditions: Non-Hodgkin's Lymphoma|Leukemia
Interventions: DRUG: Topotecan|DRUG: Mitozantrone|DRUG: Etoposide
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose:
Clinical trial: the Influence of Remote Ischemic Preconditioning on Inflammation During Human Endotoxemia
Status: COMPLETED
Conditions: Autoimmune Diseases|Infection
Interventions: OTHER: Multiple-dose Remote Ischemic Preconditioning|OTHER: Single-dose Remote Ischemic Preconditioning|BIOLOGICAL: LPS infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Massage for Prostate Cancer-Related Fatigue, mPROSTATE Study
Status: RECRUITING
Conditions: Prostate Carcinoma
Interventions: PROCEDURE: Massage Therapy|OTHER: Questionnaire Administration|PROCEDURE: Sham Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Alpha Radiation Emitters Device for the Treatment of Squamous Cell Carcinoma (DaRT)
Status: COMPLETED
Conditions: Skin Squamous Cell Carcinoma
Interventions: DEVICE: Radiation: Diffusing Alpha Radiation Emitters Therapy (DaRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: FIRE AND ICE II Trial Pilot
Status: COMPLETED
Conditions: Persistent Atrial Fibrillation|Atrial Arrhythmia
Interventions: DEVICE: Cryoballoon (Arctic Front Advance Cryoballoon)|DEVICE: Radiofrequency Catheter (ThermoCool Smarttouch)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics and Tolerability of Meloxicam Gel Compared to Meloxicam Tablets in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Meloxicam gel|DRUG: Meloxicam tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Pharmacodynamic of B12019 and Neulasta® in Healthy Subjects
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: BIOLOGICAL: Neulasta, B12019
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Auricular Acupuncture on Neonatal Abstinence Syndrome
Status: COMPLETED
Conditions: Neonatal Abstinence Syndrome
Interventions: OTHER: Auricular acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Post-marketing Surveillance of Children With Chronic Hepatitis C Treated With Intron A (Vial or Pen) and Rebetol (Study P04397)(TERMINATED)
Status: TERMINATED
Conditions: Hepatitis C, Chronic|Hepatitis C
Interventions: BIOLOGICAL: IntronA (interferon alfa-2b; SCH 30500)|DRUG: Rebetol (ribavirin; SCH 18908)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: "The Effect of Stellate Ganglion Block in Severe Brain Injury"
Status: COMPLETED
Conditions: Traumatic Brain Injury|Brain Inflammation|Cerebral Vasospasm
Interventions: PROCEDURE: one site blockade of the stellate ganglion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Medico-economic Evaluation of Therapeutic Adaptation Guided by the Soluble Suppression of Tumorigenicity 2 (sST-2) Biomarker in the Management of Patients With Acute Heart Failure
Status: RECRUITING
Conditions: Heart Failure
Interventions: BIOLOGICAL: Biomarker guided therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Reconstructing Forked Corpus Spongiosum in Hypospadias Repair
Status: UNKNOWN
Conditions: Hypospadias
Interventions: PROCEDURE: Reconstructing forked corpus spongiosum (FCS)|PROCEDURE: Routine standardized surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Validation of mμSORS for Non-invasive Blood Glucose Detection in Non-diabetic Subjects
Status: NOT_YET_RECRUITING
Conditions: Diabetes Mellitus
Interventions: DEVICE: Multi-channel Microspatial Offset Raman Scattering Spectroscopy (mμSORS) for Noninvasive Blood Glucose Detection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Phaseolus Vulgaris L. Dry Extract on the Modulation of Weight and Metabolic Parameters
Status: RECRUITING
Conditions: Weight Loss
Interventions: DIETARY_SUPPLEMENT: Phaseolus Vulgaris L. Dry Extract|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Longitudinal Study of Xenon-129 MRI Imaging Effects of Cannabis Smoking
Status: RECRUITING
Conditions: Cannabis Use|Cannabis Smoking|Marijuana Smoking|Marijuana Usage
Interventions: DIAGNOSTIC_TEST: Hyperpolarized Xenon-129 MRI of the lungs|DIAGNOSTIC_TEST: Computed Tomography (CT)|DIAGNOSTIC_TEST: Pulmonary Function Tests (PFTs)|DIAGNOSTIC_TEST: Six Minute Walk Test (6MWT)|DIAGNOSTIC_TEST: Cardiopulmonary exercise testing (CPET)|DIAGNOSTIC_TEST: Sputum analysis|DIAGNOSTIC_TEST: Blood analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety, Tolerability and Pharmacokinetics of AD16 Tablets After MAD in Healthy Chinese Adult Subjects
Status: COMPLETED
Conditions: Alzheimer Disease
Interventions: DRUG: AD16 30mg、40mg|DRUG: AD16 Placebo 30mg、40mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of the Zoster Vaccine GSK1437173A in Elderly Subjects
Status: COMPLETED
Conditions: Herpes Zoster
Interventions: BIOLOGICAL: Herpes Zoster vaccine GSK1437173A Low Dose|BIOLOGICAL: Herpes Zoster vaccine GSK1437173A Medium Dose|BIOLOGICAL: Herpes Zoster vaccine GSK1437173A High Dose|BIOLOGICAL: Herpes Zoster vaccine GSK1437173A Modified|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Drug Administration Competency of Nursing Students
Status: NOT_YET_RECRUITING
Conditions: Nursing Student|Simulation|Cognitive Load|Competence
Interventions: OTHER: Control- standard medication education|OTHER: Experiment- cognitive load theory based on medication education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Phase 1 Study to Assess the Effect of Hepatic Impairment on the Pharmacokinetics of Repotrectinib in Advanced Cancer Patients
Status: WITHDRAWN
Conditions: Locally Advanced Solid Tumor|Metastatic Solid Tumor
Interventions: DRUG: repotrectinib (TPX-0005)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Immunoradiation for Resectable Non-Small Cell Lung Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: Durvalumab|DRUG: Tremelimumab|RADIATION: Thoracic Radiation|PROCEDURE: lobectomy|DRUG: Standard of care adjuvant chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Virtual Reality-training in Theory of Mind in the Childhood Form of Myotonic Dystrophy Type 1
Status: ENROLLING_BY_INVITATION
Conditions: Myotonic Dystrophy Type 1
Interventions: OTHER: Virtual Reality-training in Theory of Mind|OTHER: Traditional training in Theory of Mind
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Intrapleural Measles Virus Therapy in Patients With Malignant Pleural Mesothelioma
Status: COMPLETED
Conditions: Recurrent Malignant Mesothelioma|Stage IA Malignant Mesothelioma|Stage IB Malignant Mesothelioma|Stage II Malignant Mesothelioma|Stage III Malignant Mesothelioma|Stage IV Malignant Mesothelioma
Interventions: BIOLOGICAL: oncolytic measles virus encoding thyroidal sodium iodide symporter|OTHER: laboratory biomarker analysis|PROCEDURE: single photon emission computed tomography|PROCEDURE: computed tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MiCrobiome dieT Study
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Medium chain triglycerides|DIETARY_SUPPLEMENT: Long chain triglycerides
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Smoking Cessation With the Nicotine Patch: A Pilot Study of Patch Messaging
Status: COMPLETED
Conditions: Smoking Cessation
Interventions: BEHAVIORAL: Telephone Counseling|DRUG: Nicotine Patches
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A National Multi-center Randomized, Open Label Study to Evaluate Efficacy and Safety of Everolimus With EC-MPS Compared to Standard Treatment Combination Tacrolimus and EC-MPS in de Novo Liver Transplant Recipients
Status: COMPLETED
Conditions: Liver Transplantation
Interventions: DRUG: tacrolimus|DRUG: everolimus|DRUG: Basiliximab|DRUG: Mycophenolic Acid|DRUG: Corticosteroids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of a Online Education Material to Improve Dengue Knowledge and Health-Seeking Intention
Status: NOT_YET_RECRUITING
Conditions: Dengue
Interventions: OTHER: DengueAid mobile application|OTHER: MyHealth website
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: A Study to Assess the Effect of Intragastric pH and Fasting on the Pharmacokinetics of Gefapixant (AF-219/MK-7264)
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Omeprazole|DRUG: Gefapixant|DRUG: Gefapixant|DRUG: Gefapixant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Impact of Intermittent Fasting on Biomarkers of Inflammation and Health-Related Quality of Life: A Feasibility Trial for Women With HR+/HER2- Early Breast Cancer
Status: RECRUITING
Conditions: Breast Cancer
Interventions: BEHAVIORAL: Intermittent Fasting
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Pomalidomide and Low Dose Dexamethasone With or Without Pembrolizumab (MK-3475) in Refractory or Relapsed and Refractory Multiple Myeloma (rrMM) (MK-3475-183/KEYNOTE-183)
Status: TERMINATED
Conditions: Multiple Myeloma
Interventions: BIOLOGICAL: Pembrolizumab|DRUG: Pomalidomide|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Determine the Bioequivalence of Alogliptin and Pioglitazone When Administered as Individual Tablets and as Fixed-Dose Combination (FDC)-SYR-322-4833 BL Tablets to Healthy Russian Participants
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Alogliptin|DRUG: Pioglitazone|DRUG: SYR-322-4833 BL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Velcade (Bortezomib, PS-341) and Rituximab in Relapsed/Refractory Mantle Cell and Follicular Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Non-Hodgkin's Lymphoma|Mantle Cell Lymphoma
Interventions: DRUG: Velcade|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: VATS ( Video-Assisted Thoracoscopy) Compared to Reinsertion of a Thoracostomy Tube for Persistent Haemothorax
Status: COMPLETED
Conditions: Haemothorax|Empyema
Interventions: PROCEDURE: VATS ( Video-Assisted Thoracoscopy )|PROCEDURE: Thoracostomy Tube reinsertion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Liposomal Anthracyclin in the Treatment of Elderly ALL
Status: COMPLETED
Conditions: Acute Lymphoblastic Leukemia
Interventions: DRUG: Doxorubicine|DRUG: Doxorubicine pegylated
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dual Therapy With High Doses of Ilaprazole and Amoxicillin for Helicobacter Pylori Infection
Status: COMPLETED
Conditions: Helicobacter Infections
Interventions: DRUG: Ilaprazole + Amoxicillin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of M640 in Acute Lumbosacral Musculoskeletal Conditions.
Status: RECRUITING
Conditions: Sciatica Acute|Lumbar Spinal Stenosis
Interventions: DRUG: Metaxalone 640 mg Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Letrozole vs. Clomiphene Citrate in Patients With Anovulatory Infertility
Status: COMPLETED
Conditions: Infertility
Interventions: DRUG: Letrozole|DRUG: Clomiphene citrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preliminary Bioequivalence Study of UHAC 62 XX Tablets Compared With a Capsule Formulation in Healthy Male Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: UHAC 62 XX - TF1 tablet|DRUG: UHAC 62 XX - TF2 tablet|DRUG: UHAC 62 XX - capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Culturally Enhancing a Motivational Interviewing Intervention For Latinx Adolescents
Status: COMPLETED
Conditions: Underage Alcohol Use|Smoking, Non-Tobacco Products
Interventions: BEHAVIORAL: GMIT|BEHAVIORAL: GMIT+
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Nilotinib Versus Standard Imatinib (400/600 mg Every Day (QD)) Comparing the Kinetics of Complete Molecular Response for Chronic Myelogenous Leukemia in Chronic Phase (CML-CP) Pts With Evidence of Persistent Leukemia by Real-time Quantitative Polymerase Chain Reaction (RQ-PCR)
Status: COMPLETED
Conditions: CHRONIC MYELOGENOUS LEUKEMIA
Interventions: DRUG: Nilotinib|DRUG: Imatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multi-classifier System for Stratifying Stage III Papillary Renal Cell Carcinoma of Receiving Adjuvant Therapy
Status: NOT_YET_RECRUITING
Conditions: Papillary Renal Cell Carcinoma
Interventions: DRUG: Pembrolizumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Two Different Stepwise Lung Recruitment Maneuvers on Patient Hemodynamics During Laproscopic Surgery
Status: COMPLETED
Conditions: Recruitment
Interventions: PROCEDURE: Recruitment maneuver with tidal volume (RM TV)|PROCEDURE: Recruitment maneuver by PEEP (RM PEEP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Ipilimumab in the Immune System
Status: COMPLETED
Conditions: Previously Untreated and Histologically Confirmed Stage III (Unresectable) or Stage IV Melanoma
Interventions: DRUG: Ipilimumab at 3 mg/kg dose
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Test the Efficacy and Safety of Bimekizumab and Certolizumab Pegol in Patients With Active Ankylosing Spondylitis
Status: COMPLETED
Conditions: Ankylosing Spondylitis
Interventions: DRUG: Bimekizumab|DRUG: Certolizumab pegol|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intraoperative Testing of Colorectal Anastomosis - Air or Water (Methylene Blue)?
Status: UNKNOWN
Conditions: ColoRectal Cancer|Colonic Diverticulitis|Anastomotic Leak|Anastomotic Complication|Anastomosis
Interventions: PROCEDURE: Intraoperative testing of colorectal anastomoses|PROCEDURE: Stapled colorectal anastomoses
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Assess the Safety and Efficacy of ASP8062 as an Add-on Therapy to Buprenorphine/Naloxone in Participants With Opioid Use Disorder
Status: WITHDRAWN
Conditions: Opioid Use Disorder
Interventions: DRUG: ASP8062|DRUG: Placebo ASP8062|DRUG: buprenorphine/naloxone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: TGFB1 And LAMA1 Gene Polymorphisms in High Myopia
Status: COMPLETED
Conditions: High Myopia|Gene Mutations
Interventions: GENETIC: TGFB1 AND LAMA1 GENE POLYMORPHISMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SCREENING
Clinical trial: Chinese Medicine for Treating Chronic Pharyngolaryngitis
Status: RECRUITING
Conditions: Chronic Pharyngolaryngitis (Disorder)
Interventions: DRUG: Qingyan Lihou Decoction|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Marine n-3 Fatty Acids on Heart Rate Variability and Arrhythmias in Patients Receiving Chronic Dialysis
Status: COMPLETED
Conditions: Kidney Failure Chronic|Arrhythmias Cardiac
Interventions: DIETARY_SUPPLEMENT: dietary supplement: n-3 PUFA|DIETARY_SUPPLEMENT: olive oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: High Versus Low Dose of Caffeine for Apnea of Prematurity
Status: COMPLETED
Conditions: Apnea|Preterm Infants
Interventions: DRUG: Caffeine citrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Long Term Effects of Nutritional Supplementation on Final Height
Status: WITHDRAWN
Conditions: Growth Disorders|Low Weight|Short Stature
Interventions: DIETARY_SUPPLEMENT: Gender specific nutritional standardized formula|OTHER: Follow-up only
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Upper Extremity Rehabilitation Training Using Brain-Machine Interface Biofeedback in Stroke Patients With Hemiplegia
Status: UNKNOWN
Conditions: Stroke|Hemiplegia
Interventions: DEVICE: BMI-assisted motor imagery OT|OTHER: Motor imagery OT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Role of Methylphenidate on Performance in the Cold
Status: UNKNOWN
Conditions: Hypothermia|Exercise Test|Cognition
Interventions: DRUG: Methylphenidate|DRUG: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Dual Guidance Structure for Evaluation of Patients With Unclear Diagnosis in Centers for Rare Diseases
Status: COMPLETED
Conditions: Rare Diseases|Orphan Diseases
Interventions: OTHER: dual expert guidance structure
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Effect of the Modified Simulation Model on Self-Efficacy, Anxiety, and Academic Motivation in Episiotomy Training
Status: NOT_YET_RECRUITING
Conditions: Episiotomy|Anxiety|Simulation
Interventions: OTHER: Episio Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Frailty Phenotype Assessments to Optimize Treatment Strategies for Older Patients With Hematologic Malignancies
Status: RECRUITING
Conditions: Leukemia, Acute|MDS
Interventions: PROCEDURE: Bone Marrow or Peripheral Blood Graft (BMT)|OTHER: Cancer-directed Therapy or Best Supportive Care|DIAGNOSTIC_TEST: Frailty Assessment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p