pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Valproate and Etoposide for Patients With Neuronal Tumors and Brain Metastases
Status: COMPLETED
Conditions: Neuroectodermal Tumor|Brain Metastases|Advanced Cancer
Interventions: DRUG: Valproate|DRUG: Etoposide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Drug Letermovir (LTV) as Prevention for Recurrent of Cytomegalovirus (CMV) Infection
Status: ACTIVE_NOT_RECRUITING
Conditions: CMV|CMV Infection|Hematopoietic Cell Transplant
Interventions: DRUG: Letermovir Pill|OTHER: blood draw
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 3 Study of Imiquimod Creams in the Treatment of External Genital Warts
Status: COMPLETED
Conditions: Genital Warts
Interventions: DRUG: 2.5% imiquimod cream|DRUG: 3.75% imiquimod cream|DRUG: Placebo cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Daily Bathing With Chlorhexidine in the Critical Patient
Status: UNKNOWN
Conditions: Healthcare Associated Infections
Interventions: OTHER: Daily baths with chlorhexidine wipes, oral spray and standard shampoo|OTHER: Daily baths with placebo wipes, oral spray and shampoo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: NPC-12G Gel 0.2% Sirolimus PK Bridging Study
Status: COMPLETED
Conditions: Bioavailability Study
Interventions: DRUG: NPC-12G Gel 0.2%|DRUG: Rapamune® 2 mg tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Gallium-68 PSMA-11 PET in Participants With Prostate Cancer
Status: WITHDRAWN
Conditions: Metastatic Prostate Carcinoma|Recurrent Prostate Carcinoma|Stage IV Prostate Cancer AJCC v8|Stage IVA Prostate Cancer AJCC v8|Stage IVB Prostate Cancer AJCC v8
Interventions: PROCEDURE: Computed Tomography|DRUG: Gallium Ga 68-labeled PSMA-11|PROCEDURE: Magnetic Resonance Imaging|PROCEDURE: Positron Emission Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluating Treatment of Anemia in Subjects With Non-Myeloid MalignanciesReceiving Multicycle Chemotherapy
Status: COMPLETED
Conditions: Anemia|Non-Myeloid Malignancies|Cancer
Interventions: DRUG: Darbepoetin alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the MiniMed 780 System in Paediatric Subjects
Status: ACTIVE_NOT_RECRUITING
Conditions: Diabetes type1|Children, Only
Interventions: DEVICE: Study Phase: MiniMed 780G Auto Mode with G4S sensor|DEVICE: Study Phase: MiniMed 780G Manual Mode with G4S sensor|DEVICE: Continuation phase: MiniMed 780G BLE 2.0 with DS5 sensor|DEVICE: Continuation Phase MiniMed 780G Auto Mode with G4S sensor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High-intensity Interval Training Enhances Mobilization/Functionality of Endothelial Progenitor Cells and Depressed Shedding of Vascular Endothelial Cells Undergoing Hypoxia
Status: COMPLETED
Conditions: Hypoxia
Interventions: BEHAVIORAL: HIT|BEHAVIORAL: MCT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Left Atrial Cryoablation Enhanced by Ganglionated Plexi Ablation in the Treatment of Atrial Fibrillation
Status: COMPLETED
Conditions: Mitral Valve Disease|Coronary Artery Disease|Tricuspid Valve Disease|Aortic Valve Disease|Atrial Fibrillation
Interventions: PROCEDURE: Concomitant Mapping and Radiofrequency Ablation|PROCEDURE: No intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Perioperative Chemo and Pembrolizumab in Gastric Cancer
Status: COMPLETED
Conditions: Gastric Cancer|Adenocarcinoma of the Gastroesophageal Junction
Interventions: DRUG: Pembrolizumab|DRUG: Standard of care chemotherapy regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Varenicline Treatment for Excessive Daytime Sleepiness in Parkinson's Disease
Status: TERMINATED
Conditions: Parkinson's Disease
Interventions: DRUG: Varenicline|DRUG: Placebo (for varenicline)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Efficacy and Safety Evaluation of the Drug Imescard Compound Water Smartweed Pills
Status: UNKNOWN
Conditions: Chronic Constipation|Hemorrhoids
Interventions: DRUG: Imescard water smartweed composed pills|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Placebo-controlled Safety and Efficacy Study of Pregabalin in Subjects With Post-traumatic Peripheral Neuropathic Pain
Status: COMPLETED
Conditions: Neuropathic Pain
Interventions: DRUG: pregabalin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Z Technıque on Pain, Comfort, Symptoms in Ummunotherapy Areas
Status: COMPLETED
Conditions: Immunotherapy
Interventions: OTHER: Pre-post test|BEHAVIORAL: experimental group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: TRADE: Dose Escalation Tolerability of Abemaciclib in HR+ HER2- Early Stage Breast Cancer
Status: RECRUITING
Conditions: Breast Cancer|Early-stage Breast Cancer|High Risk Breast Carcinoma
Interventions: DRUG: Abemaciclib|DRUG: Tamoxifen|DRUG: Anastrozole|DRUG: Letrozole|DRUG: Exemestane|DRUG: LHRH Agonist
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testing the Addition of the Drug Atezolizumab to the Usual Radiation Treatment for Patients With Early Non-small Cell Lung Cancer
Status: SUSPENDED
Conditions: Lung Non-Small Cell Carcinoma|Stage I Lung Cancer AJCC v8|Stage II Lung Cancer AJCC v8
Interventions: DRUG: Atezolizumab|PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|OTHER: Fludeoxyglucose F-18|PROCEDURE: Positron Emission Tomography|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration|RADIATION: Stereotactic Body Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy & Safety of a 2nd Series of Low Intensity Shock Waves for ED on Partial Responders to First Treatment
Status: UNKNOWN
Conditions: Erectile Dysfunction
Interventions: DEVICE: Low Intensity Extracorporeal Shock waves (Cardiospec 1000)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gene Modified Allogeneic Neuroblastoma Cells For Treatment of Relapsed/Refractory Neuroblastoma
Status: COMPLETED
Conditions: Neuroblastoma
Interventions: DRUG: Interleukin-2
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sex Hormones and Atherosclerosis Prevention in Perimenopausal Women
Status: COMPLETED
Conditions: Arterial Stiffening|Aging|Menopause
Interventions: DRUG: GnRHant - Ganirelix acetate|DRUG: Transdermal estradiol patch|DRUG: Transdermal placebo patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Safety, Tolerability, and Efficacy Study of VX-880 in Participants With Type 1 Diabetes
Status: RECRUITING
Conditions: Diabetes Mellitus, Type 1|Impaired Hypoglycemic Awareness|Severe Hypoglycemia
Interventions: BIOLOGICAL: VX-880
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Determination of the Optimal Size of Oropharyngeal Airway; Correlation With External Body Measurements
Status: COMPLETED
Conditions: Ear,Nose and Throat Surgery
Interventions: DEVICE: Guedel type color-coded OPAs
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Sensory Modulation Dysfunction and Posttraumatic Stress Disorder
Status: RECRUITING
Conditions: Posttraumatic Stress Disorder|Sensory Processing Disorder
Interventions: BEHAVIORAL: The Trauma Film Paradigm|BEHAVIORAL: non-traumatic (neutral) film
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Video-Assisted Discharge Education After Total Hip Replacement Surgery
Status: COMPLETED
Conditions: Total Hip Replacement|Patient Education|Patient Satisfaction|Activities of Daily Living
Interventions: BEHAVIORAL: Video-Assisted Discharge Education (VADE)|BEHAVIORAL: Physiotherapy (PT) Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Withdrawal Exposure With Withdrawal Regulation Training for Smoking Cessation
Status: COMPLETED
Conditions: Smoking Cessation
Interventions: BEHAVIORAL: Withdrawal regulation training|BEHAVIORAL: Relaxation training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Extracellular Vesicles Infusion Treatment for Mild-to-Moderate COVID-19
Status: WITHDRAWN
Conditions: COVID-19
Interventions: DRUG: ExoFlo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Relative Bioavailability Study of Ramipril 10 mg Capsules Under Fed Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Ramipril10 mg Capsules, single dose|DRUG: Atlace® 10 mg capsules, single dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: High-Dose Statin Combined With Telmisartan vs Amlodipine on Glucose Metabolism in ASCVD Patients With IFG and Hypertension
Status: COMPLETED
Conditions: ASCVD|Impaired Fasting Glucose|Hypertension
Interventions: DRUG: Duowell®|DRUG: Monorova® + Amlopin®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fasting Study of Glimepiride Tablets 1 mg to Amaryl® Tablets 1 mg
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Glimepiride Tablets 1 mg|DRUG: Amaryl® Tablets 1 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Application of Vaginal Manipulator in Abdominal Hysterectomy Operations
Status: COMPLETED
Conditions: Abdominal Hysterectomy
Interventions: PROCEDURE: Manipulation of vagina during abdominal hysterectomy operation|PROCEDURE: Classical conventional abdominal hysterectomy operation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Effects of Two Different Exercise Programs in Office Workers
Status: COMPLETED
Conditions: Physical Activity|Exercise|Office Worker|Lower Extremity Function|Posture
Interventions: OTHER: Functional exercises|OTHER: Posture exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Relative Bioavailability of a New Formulation of BCX4161 and the Effect of Food on BCX4161
Status: COMPLETED
Conditions: Hereditary Angioedema
Interventions: DRUG: BCX4161
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of Rozanolixizumab in Adult Participants With Myelin Oligodendrocyte Glycoprotein (MOG) Antibody-associated Disease (MOG-AD)
Status: RECRUITING
Conditions: Myelin Oligodendrocyte Glycoprotein Antibody-associated Disease (MOG-AD)
Interventions: DRUG: Rozanolixizumab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Strength Training for Chronic Low Back Pain Patients (IRMA20)
Status: COMPLETED
Conditions: Musculoskeletal Pain|Low Back Pain
Interventions: BEHAVIORAL: Strength training|BEHAVIORAL: Usual care (control)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Gene Therapy for Pleural Malignancies
Status: COMPLETED
Conditions: Pleural Mesothelioma|Metastatic Pleural Effusions
Interventions: BIOLOGICAL: Adenoviral-mediated Interferon-beta|BIOLOGICAL: SCH 721015
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Modulation of Immune Response by Oral Zinc Supplementation in Chemotherapy for Colon Cancer
Status: UNKNOWN
Conditions: Adjuvant Chemotherapy|Colon Cancer|Immunity
Interventions: DIETARY_SUPPLEMENT: zinc|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Ibuprofen Lozenge in Acute Sore Throat Pain
Status: COMPLETED
Conditions: Acute Sore Throat Pain
Interventions: DRUG: Ibuprofen 25 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Adductor Canal Block and Arthroscopic Knee Surgery, High Pain Responders
Status: COMPLETED
Conditions: Arthroscopic Knee Surgery
Interventions: PROCEDURE: Intervention group, block no. 1 - Ropivacain|PROCEDURE: Control group: 1. block - saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Safety of DWP16001 Compared to Placebo in the Treatment of Type 2 Diabetes Mellitus.
Status: COMPLETED
Conditions: T2DM (Type 2 Diabetes Mellitus)
Interventions: DRUG: DWP16001
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Dexmedetomidine on Postoperative Quality of Recovery
Status: UNKNOWN
Conditions: The Effect of Dexmedetomidine on Postoperative Quality of Recovery
Interventions: DRUG: Dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Controlled Study of Solriamfetol for Attention Deficit Hyperactivity Disorder (ADHD) in Adults
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: DRUG: Solriamfetol 75 MG|DRUG: Solriamfetol 150 MG|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Aqualief® in Patients With Xerostomia as Consequence of Radiotherapy for Head and Neck Cancer
Status: TERMINATED
Conditions: Xerostomia|Asialia|Hyposalivation|Mouth Dryness
Interventions: DIETARY_SUPPLEMENT: Aqualief|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cardiovascular Complications and COVID-19 (CovCardioVasc-Study)
Status: UNKNOWN
Conditions: COVID|Acute Coronary Syndrome|Myocardial Infarction|Myocarditis|Venous Thromboembolism|Deep Vein Thrombosis|Pulmonary Embolism
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The QUebec Adipose and Lifestyle InvesTigation in Youth (QUALITY) Cohort
Status: ACTIVE_NOT_RECRUITING
Conditions: Obesity, Childhood|Diabetes Mellitus, Type 2|Cardiovascular Risk Factor|Pediatric ALL|Lifestyle|Physical Activity|Sedentary Lifestyle|Diet Habit|Metabolic Complication
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Clinical Trial to Evaluate PCS499 in Treating Ulcerations in Patients Who Have Necrobiosis Lipoidica
Status: TERMINATED
Conditions: Necrobiosis Lipoidica
Interventions: DRUG: PCS499|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: IVIG Versus Plasmapheresis in the Treatment of Guillian Barrie Syndrome Patients
Status: COMPLETED
Conditions: Guillain-Barre Syndrome
Interventions: DEVICE: plasmapheresis device|DRUG: Intravenous immunoglobulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Drug Interaction Study With Dabigatran Etexilate and Dronedarone in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Dabigatran etexilate plus dronedarone|DRUG: Dabigatran etexilate|DRUG: Dabigatran etexilate plus dronedarone|DRUG: Dabigatran etexilate plus dronedarone|DRUG: Dabigatran etexilate plus dronedarone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: LS301 Uptake in Tumors of Patients Undergoing Liver, Pancreas, or Gastric Surgery
Status: WITHDRAWN
Conditions: Pancreatic Cancer|Liver Cancer|Gastric Cancer|Gastrointestinal Stromal Cancer|Metastatic Cancer
Interventions: DRUG: LS301|DEVICE: Cancer Vision Goggles
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: DIAGNOSTIC
Clinical trial: Increasing Optimal Use of HPV Vaccination in Primary Care
Status: COMPLETED
Conditions: Human Papillomavirus Vaccines
Interventions: OTHER: Practice Facilitation|OTHER: Education|OTHER: Audit and Feedback|OTHER: Communication Strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: ALT-801 in Overweight and Obese Subjects With Type 2 Diabetes Mellitus (T2DM)
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: ALT-801|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intraoperative Radiation Therapy for Resectable Pancreas Cancer
Status: UNKNOWN
Conditions: Pancreas Cancer
Interventions: RADIATION: 10 Gy Low-KV IORT|RADIATION: 15 Gy Low-KV IORT|RADIATION: 20 GY Low-KV IORT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MGTA-456 in Patients With Inherited Metabolic Disorders Undergoing Hematopoietic Stem Cell Transplantation (HSCT)
Status: COMPLETED
Conditions: Inherited Metabolic Disorders (IMD)
Interventions: DRUG: MGTA-456
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Systemic and Local Diffusion of Ethanol After Administration of Ethanol 96% Formulated in a Gel and Ethanol 98% Solution by the Percutaneous Route, in Patients With Congenital Venous Malformations:Pharmacokinetic, Pharmacodynamic and Clinical Study.
Status: COMPLETED
Conditions: Congenital Venous Malformation
Interventions: DRUG: Ethanol 96% Gel|DRUG: Ethanol 98% Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Botulinum Toxin Type A Block of the Sphenopalatine Ganglion in Chronic Rhinosinusitis With Nasal Polyposis
Status: COMPLETED
Conditions: Chronic Disease|Nasal Polyposis|Rhinitis
Interventions: DRUG: botox injection Multiguide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antegrade and Retrograde Versurs Antegrade Cardioplegia in Complex Coronary Artery Bypass Surgeries
Status: UNKNOWN
Conditions: Coronary Artery Disease Left Main
Interventions: PROCEDURE: retrograde cardioplegia protection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: ADVANCE Study of DTG + TAF + FTC vs DTG + TDF + FTC and EFV + TDF+FTC in First-line Antiretroviral Therapy
Status: COMPLETED
Conditions: HIV-1 Infection
Interventions: DRUG: Dolutegravir|DRUG: Tenofovir Alafenamide|DRUG: Truvada|DRUG: Atripla
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non-invasive Diagnosis of Coronary Microvascular Disease: Pilot Study
Status: RECRUITING
Conditions: Microvascular Angina
Interventions: DIAGNOSTIC_TEST: Coronary microvascular disease testing during coronary angiography|DIAGNOSTIC_TEST: Cardiac magnetic resonance scan including exercise|DIAGNOSTIC_TEST: Additional analysis of already acquired CT scan
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pilot Study of Autologous Anti-EGFRvIII CAR T Cells in Recurrent Glioblastoma Multiforme
Status: UNKNOWN
Conditions: Glioblastoma Multiforme
Interventions: BIOLOGICAL: anti-EGFRvIII CAR T cells|DRUG: cyclophosphamide|DRUG: Fludarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized Pilot Trial Evaluating the Impact of a Yoga Intervention on Cognition in Older Adults Infected With HIV
Status: COMPLETED
Conditions: HIV/AIDS|Cognitive Impairment|Aging|Mobility Limitation|Medication Adherence|Depression|Quality of Life|Balance Problems
Interventions: OTHER: Yoga-mindfulness
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Optimization of a mHealth Physical Activity Promotion Intervention With Mindful Awareness for AYAO (OPT2MOVE)
Status: RECRUITING
Conditions: Cancer
Interventions: BEHAVIORAL: Core Intervention|BEHAVIORAL: E-Coach|BEHAVIORAL: General Mindfulness Training|BEHAVIORAL: MVPA-Specific Mindfulness Training|BEHAVIORAL: Buddy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Relevance Evaluation of [68Ga]Ga-PentixaFor for Initial Staging and Detection of Minimal Residual Disease in Multiple Myeloma Patients.
Status: WITHDRAWN
Conditions: Multiple Myeloma
Interventions: DRUG: [68Ga]Ga-PentixaFor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety and Activity of PolyPEPI1018 Plus Atezolizumab in Colorectal Cancer.
Status: ACTIVE_NOT_RECRUITING
Conditions: Colorectal Cancer Metastatic
Interventions: DRUG: PolyPEPI1018|DRUG: Atezolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of USG-Guided Coccygeal Nerve Block on Sacrococcygeal and/or Intercoccygeal Joint Injection for Coccydynia
Status: RECRUITING
Conditions: Coccyx Disorder|Coccygodynia|Coccyx Injury
Interventions: PROCEDURE: Ultrasound-guided sacrococcygeal and/or intercoccygeal joint injection|PROCEDURE: Ultrasound-guided coccygeal nerve block|PROCEDURE: Ultrasound-guided sacrococcygeal and/or intercoccygeal joint injection after coccygeal nerve block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CaptHPV : Validation of the Method "CaptHPV" for the Diagnosis of Human Papillomavirus Associated Infiltrating Carcinomas
Status: COMPLETED
Conditions: Cervical Cancer|Vulvar Cancer|Anal Cancer|Oropharynx Cancer|Oral Cavity Cancer|Penis Cancer
Interventions: OTHER: CaptHPV method
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study the Efficacy and Safety of VAY736 and CFZ533 in SLE Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Systemic Lupus Erythematosus (SLE)
Interventions: DRUG: VAY736|DRUG: VAY736 Placebo|DRUG: CFZ533|DRUG: CFZ533 Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Perioperative Analgesia Using Ultrasound (US) Guided Transversus Abdominis Plane (TAP) Block
Status: UNKNOWN
Conditions: Postoperative Pain
Interventions: DRUG: Bupivacaine|OTHER: TAP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study on the Timing of FOLFOX for Patients With Operable, Node Positive Rectal Cancer
Status: COMPLETED
Conditions: Operable T2-3N+M0 Rectal Cancer (Stage III)
Interventions: DRUG: FOLFOX|RADIATION: high dose rate endorectal brachytherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nutrition, Arsenic and Cognitive Function in Children
Status: COMPLETED
Conditions: Arsenic Exposure
Interventions: DIETARY_SUPPLEMENT: Vitamin B12|DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: Folic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Ketogenic Diet as Adjunctive Treatment in Refractory/End-stage Glioblastoma Multiforme: a Pilot Study
Status: COMPLETED
Conditions: Glioblastoma Multiforme
Interventions: OTHER: ketogenic diet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Knee Swelling Under Use of Compression Stockings After Outpatient Surgery
Status: COMPLETED
Conditions: Knee Pain Swelling
Interventions: OTHER: Patients use compression stockings for 10 days after surgery|OTHER: normal therapy - no compression stockings
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Estimating Blood Loss Using TritonTM in Vaginal Deliveries: A Validation Trial
Status: TERMINATED
Conditions: Post Partum Hemorrhage|Blood Loss|Vaginal Bleeding|Vaginal Delivery
Interventions: DEVICE: Triton L and D system for estimation of blood loss at time of vaginal delivery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Test the Benefit of a New Anti-cancer Treatment in Patients With Unresectable Advanced Melanoma
Status: COMPLETED
Conditions: Melanoma
Interventions: BIOLOGICAL: Immunotherapeutic GSK2132231A
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Clinical Observational Cohort Study to Evaluate the Use of a Tissue Separating Mesh (Proceed®) in Laparoscopic Ventral Hernia Repair
Status: COMPLETED
Conditions: Ventral Hernia
Interventions: PROCEDURE: use of a tissue separating mesh (Proceed®) in Laparoscopic Ventral hernia repair
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: AZD2171 and Temsirolimus in Patients With Advanced Gynecological Malignancies
Status: COMPLETED
Conditions: Endometrial Cancer|Ovarian Cancer|Cervical Cancer|Fallopian Tube Cancer|Peritoneal Cancer
Interventions: DRUG: temsirolimus|DRUG: cediranib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Trial of Alprazolam 0.5 mg Tablets
Status: COMPLETED
Conditions: Anxiety Disorders
Interventions: DRUG: Alprazolam 0.5 mg|DRUG: Alprazolam 0.5 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Vigorous or Moderate Exercise in Enhancing Active Surveillance in Patients With Localized Prostate Cancer
Status: WITHDRAWN
Conditions: Recurrent Prostate Cancer|Stage I Prostate Cancer|Stage IIA Prostate Cancer|Stage IIB Prostate Cancer
Interventions: BEHAVIORAL: moderate exercise intervention|BEHAVIORAL: vigorous exercise intervention - standard|OTHER: questionnaire administration|OTHER: laboratory biomarker analysis|BEHAVIORAL: vigorous exercise intervention - cybercycling|BEHAVIORAL: Exercise Logs|BEHAVIORAL: Adherence|BEHAVIORAL: Exercise and body composition test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: GM-CSF Mouthwash for Preventing and Treating Mucositis in Patients Undergoing Radiation Therapy for Head and Neck Cancer
Status: COMPLETED
Conditions: Head and Neck Cancer|Mucositis Oral|Radiation Toxicity|Tongue Cancer
Interventions: BIOLOGICAL: sargramostim|OTHER: oral salt and soda mouthwash
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of Modified Radical Endoscopic Sinus Surgery on Eosinopilic Chronic Rhinosinusitus With Nasal Polyps
Status: RECRUITING
Conditions: Chronic Sinusitis|Endoscopic Sinus Surgery|Nasal Polyps
Interventions: PROCEDURE: Modified radical endoscopic sinus surgery|PROCEDURE: functional endoscopic sinus surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Target Hemodynamics and Brain Injury During General Anesthesia in the Elderly
Status: SUSPENDED
Conditions: Post-operative Cognitive Dysfunction
Interventions: PROCEDURE: Hemodynamic target|DRUG: Phenylephrine|DRUG: Intravenous fluids|PROCEDURE: Patient's positioning|PROCEDURE: Reduction of depth of anesthesia|DRUG: Ephedrine|DRUG: Epinephrine|DRUG: Norepinephrine|DRUG: Dopamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Improving Risk Assessment of AML With a Precision Genomic Strategy to Assess Mutation Clearance
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Cytarabine|PROCEDURE: Allogeneic stem cell transplant|PROCEDURE: Bone marrow aspiration|PROCEDURE: Punch skin biopsy|DEVICE: ClinSeq
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TGF-beta Resistant Cytotoxic T-lymphocytes in Treatment of EBV-positive Nasopharyngeal Carcinoma / RESIST-NPC
Status: ACTIVE_NOT_RECRUITING
Conditions: EBV-positive Nasopharyngeal Carcinoma
Interventions: BIOLOGICAL: DNR.NPC-specific T cells|BIOLOGICAL: DNR.NPC-specific T cells + cyclophosphamide + fludarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Nigella Sativa on Lipid Profiles in Elderly
Status: COMPLETED
Conditions: Dyslipidemia
Interventions: DRUG: Nigella sative|DIETARY_SUPPLEMENT: black sticky rice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: EUS-guided Fine Needle Biopsy With a New Core Histology Needle Versus Conventional Fine Needle Aspiration
Status: COMPLETED
Conditions: Pancreas Adenocarcinoma|Pancreas Neoplasms|Gastrointestinal Stromal Tumor|Lymphoma
Interventions: DEVICE: Fine needle biopsy using ProCore needle for histology.|DEVICE: Fine needle aspiration using conventional FNA for cytology
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Epley Manoeuvre in Participants With Multiple Sclerosis Diagnosed From Benign Paroxysmal Positional Vertigo
Status: UNKNOWN
Conditions: Benign Paroxysmal Positional Vertigo|Multiple Sclerosis
Interventions: PROCEDURE: Epley Manoeuvre|PROCEDURE: Sham Manoeuvre
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Low Volume PEG-Asc and Lower Volume PEG-Asc With Bisacodyl
Status: COMPLETED
Conditions: Bowel Disease|Colon Adenoma
Interventions: DRUG: Polyethylene Glycols|DRUG: Bisacodyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose:
Clinical trial: A Clinical Assessment of the Hemacopolymer Daily Disposable Limbal Ring Soft Contact Lens
Status: COMPLETED
Conditions: Myopia
Interventions: DEVICE: Hema-copolymer Lens|DEVICE: etafilcon A Lens
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Atomized Intranasal Vs Intravenous Ketorolac in Acute Renal Colic Pain Management.
Status: COMPLETED
Conditions: Acute Renal Colic
Interventions: DRUG: Intravenous Ketorolac Tromethamine|DRUG: Intranasal Ketorolac Tromethamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Lenalidomide Plus R-CHOP Chemotherapy Versus Placebo Plus R-CHOP Chemotherapy in Untreated ABC Type Diffuse Large B-cell Lymphoma
Status: COMPLETED
Conditions: Lymphoma, Large B-Cell, Diffuse
Interventions: DRUG: lenalidomide|DRUG: Placebo|DRUG: Rituximab|DRUG: Cyclophosphamide|DRUG: Doxorubicin|DRUG: prednisone|DRUG: vincristine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cost Effectiveness of Various Implant Placement Protocols in the Esthetic Zone
Status: NOT_YET_RECRUITING
Conditions: Esthetic Zone|Single Tooth Lost|Accuracy of Dental Implants|Dimensional Changes|Patient Reported Outcome Measures|Implant Survival and Success|Cost-effectiveness|Cost-Benefit Analysis|Complications|Frequency of Treatment Protocol|Single Tooth Dental Implant
Interventions: PROCEDURE: Immediate Implant Placement|PROCEDURE: Early Implant Placement|PROCEDURE: Late Implant Placement
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Radio-labeled huA33 Antibody in Colorectal Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Colorectal Neoplasms|Colorectal Cancer|Colorectal Tumor|COlorectal Carcinoma
Interventions: DRUG: Iodine-124 labeled humanized A33 (antibody)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Semaglutide and Vascular Regeneration
Status: RECRUITING
Conditions: Atherosclerosis|Cardiovascular Diseases|Diabetes Mellitus, Type 2|Obesity
Interventions: DRUG: Semaglutide Pen Injector
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Walking Stick Exercise in Patients Underwent Total Knee Arthroplasty
Status: ENROLLING_BY_INVITATION
Conditions: Arthroplasty|Replacement|Knee Osteoarthritis
Interventions: OTHER: Walking stick exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Computerized Tomography (CT) Scan Study of Bone Healing Following Open Wedge Proximal Tibial Osteotomy
Status: COMPLETED
Conditions: Osteoarthritis|Varus Malalignment
Interventions: PROCEDURE: Ellipse IM HTO Nail|PROCEDURE: TomoFix
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Botulinum Toxin Injection Guided by Ultrasound Combined With Balloon Localization on Cricopharyngeal Achalasia
Status: RECRUITING
Conditions: Cricopharyngeal Achalasia|Dysphagia
Interventions: DRUG: Botulinum toxin type A for injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of Expectations on Change in Pain Perception After a 3 Min Wallsquat Exercise.
Status: COMPLETED
Conditions: Pain|Physical Activity
Interventions: OTHER: Hypoalgesia expectation|OTHER: Hyperalgesia expectation|OTHER: Neutral
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Early Enteral Tube Feedings in Children Receiving Chemo for AML/MDS & High Risk Solid Tumors
Status: WITHDRAWN
Conditions: Brain and Central Nervous System Tumors|Kidney Cancer|Leukemia|Liver Cancer|Neuroblastoma|Sarcoma|Solid Tumor
Interventions: DIETARY_SUPPLEMENT: nutritional intervention|DIETARY_SUPPLEMENT: therapeutic nutritional supplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety & Efficacy of EPO-018B for the Treatment of Anemia in Participants With Chronic Kidney Diseases Not on Dialysis
Status: UNKNOWN
Conditions: Chronic Renal Failure|Chronic Kidney Disease|Anemia
Interventions: DRUG: EPO-018B
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Botulinum Toxins Intralesional Injection for Scar Pain
Status: UNKNOWN
Conditions: Scar Keloid|Hypertrophic Scar
Interventions: DRUG: Triamcinolone|DRUG: Lidocaine|DRUG: Botulinum toxin A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Movement Pattern Biofeedback Training After Total Knee Arthroplasty
Status: ACTIVE_NOT_RECRUITING
Conditions: Total Knee Arthroplasty|Older Adults
Interventions: BEHAVIORAL: MOVE|BEHAVIORAL: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Sterile Compound C31510 for Injection to Subjects With Solid Tumors
Status: COMPLETED
Conditions: Solid Tumors
Interventions: DRUG: Sterile Compound C31510 for Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Programmed Intermittent Epidural Bolus for Labor Analgesia During First Stage of Labor
Status: COMPLETED
Conditions: Labor Pain
Interventions: DRUG: Bupivacaine|DRUG: Fentanyl|DEVICE: Infusion pump
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: VIVITROL as a Treatment for Cocaine and Alcohol Dependence
Status: COMPLETED
Conditions: Cocaine Dependence|Alcohol Dependence
Interventions: DRUG: VIVITROL (Naltrexone extended-release injectable suspension)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Long-term Follow-up of Long-acting Cabotegravir (CAB LA) for PrEP (Pre-exposure Prophylaxis) in Participants at Risk of Acquiring HIV (Human Immunodeficiency Virus)
Status: NOT_YET_RECRUITING
Conditions: HIV Infections
Interventions: DRUG: CAB LA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Adjuvant Leuprolide With or Without Docetaxel in High Risk Prostate Cancer After Radical Prostatectomy
Status: COMPLETED
Conditions: Prostatic Neoplasms
Interventions: DRUG: Docetaxel (TAXOTERE®) Chemotherapy|DRUG: Leuprolide acetate ( ELIGARD®) Hormonal Therapy|DRUG: Docetaxel (TAXOTERE®) Chemotherapy|DRUG: Leuprolide acetate ( ELIGARD®) Hormonal Therapy|DRUG: Leuprolide acetate ( ELIGARD®) Hormonal Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasound-guided Lumbar Erector Spinae Plane Block in Patients Undergoing Lower Limb Vascular Surgery
Status: UNKNOWN
Conditions: Anesthesia, Local
Interventions: OTHER: Erector Spinae plane block
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Metal-metal Articulations Versus Standard 28 mm Cementless Total Hip Arthroplasty
Status: UNKNOWN
Conditions: Osteoarthritis, Hip
Interventions: DEVICE: articular surface replacement ASR, DePuy|DEVICE: ReCap/Magnum modular head, Biomet|DEVICE: Bimetric stem, mallory/head cup, 28 mm ceramic head, Biomet|DEVICE: 28 mm CrCo head, Trilogy CH cup, VerSys Fiber stem,Zimmer)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Impaction of Exercise Training on Bone Mineral Density in Patients After Total Knee Arthroplasty
Status: COMPLETED
Conditions: Knee Osteoarthritis|Arthropathy of Knee
Interventions: OTHER: exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Observational Pharmaco-Epidemiology Research & Analysis
Status: RECRUITING
Conditions: Chronic Disease|HIV/AIDS|Liver Diseases|Inflammatory Bowel Diseases|Cardiovascular Diseases|Rheumatic Diseases|Neurodegenerative Diseases
Interventions: OTHER: Non-interventional (observational only)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Assess the Safety and Tolerability of Single Doses of AZD4076 in Healthy Male Subjects
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-alcoholic Steatohepatitis (NASH)
Interventions: DRUG: AZD4076|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: 24/7 Closed-loop in Older Subjects With Type 1 Diabetes
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus|Hypoglycemia|Arrythmia
Interventions: DEVICE: Hybrid closed-loop system (CamAPS FX)|DEVICE: Sensor augmented pump therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Shoulder Adhesive Capsulitis and Ambulatory Continuous Interscalene Nerve Blocks
Status: TERMINATED
Conditions: Adhesive Capsulitis|Post-operative Pain
Interventions: PROCEDURE: Interscalene catheter with Ropivicaine or normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating The Safety And Clinical Efficacy Of Elderberry Extract In Patients With Influenza
Status: COMPLETED
Conditions: Influenza, Human
Interventions: DRUG: Elderberry Extract|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II Study to Evaluate Modified Folfirinox and Stereotactic Body Radiation Therapy in Non-metastatic Unresectable Pancreatic Adenocarcinoma
Status: RECRUITING
Conditions: Pancreatic Cancer
Interventions: DRUG: mFOLFIRINOX|RADIATION: Stereotactic body radiotherapy (SBRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Indacaterol EfectIveness In COPD Patients With Tuberculosis History
Status: COMPLETED
Conditions: Patients With Moderate-to-severe COPD With Destroyed Lung by Tuberculosis
Interventions: DRUG: Indacaterol|DRUG: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: RCT for Women With a Persisting Pregnancy of Unknown Location
Status: TERMINATED
Conditions: Persistent Pregnancy of Unknown Location|Ectopic Pregnancy
Interventions: DRUG: Methotrexate|PROCEDURE: Uterine Evacuation|OTHER: Expectant Management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Pharmacokinetic Characteristics of AD-101 in Healthy Volunteers
Status: COMPLETED
Conditions: Osteoporosis
Interventions: DRUG: AD-101 45mg|DRUG: Raloxifene 60mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT