pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Phase II/III Study of the Tolerance and Efficacy of Combined Use of Didanosine (2',3'-Dideoxyinosine; ddI) and Lentinan in HIV-Positive Patients
Status: UNKNOWN
Conditions: HIV Infections
Interventions: DRUG: Lentinan|DRUG: Didanosine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: Oxytocin Antagonist in Patients With Repeated Failure of Implantation
Status: COMPLETED
Conditions: Implantation Failure
Interventions: DRUG: Atosiban|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Buccal Infiltration Administration of Clonidine on the Success Rate of Inferior Alveolar Nerve Block
Status: WITHDRAWN
Conditions: Symptomatic Irreversible Pulpitis
Interventions: DRUG: Clonidine|DRUG: Articaine Hydrochloride + Epinephrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of Microdosing Carboplatin in Lung or Bladder Cancer
Status: TERMINATED
Conditions: Carcinoma, Non-Small-Cell Lung|Urinary Bladder Neoplasms
Interventions: DRUG: Carbon-14-labeled carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Continuous Positive Airway Pressure (CPAP) on Systemic Blood Pressure, Coagulability and Carotid Intima-media Thickness in Patients With Sleep Apnea
Status: COMPLETED
Conditions: Obstructive Sleep Apnoea
Interventions: DEVICE: Continuous Positive Airway pressure|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bismuth-Metronidazole Triple Therapy for H. Pylori First-line Treatment
Status: UNKNOWN
Conditions: Helicobacter Pylori Infection
Interventions: DRUG: Rabeprazole|DRUG: Bismuth potassium citrate|DRUG: Metronidazole|DRUG: Amoxicillin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Customized Adjuvant Chemotherapy (GECP-SCAT)
Status: COMPLETED
Conditions: Non-small-cell Lung Cancer
Interventions: DRUG: Docetaxel/Cisplatin|DRUG: Docetaxel|DRUG: Gemcitabine/Cisplatin|DRUG: Docetaxel/Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 4-[18F]Fluoroglutamine PET/CT in Imaging Patients With Newly Diagnosed Lung Cancer or Indeterminate Pulmonary Nodules
Status: UNKNOWN
Conditions: Lung Cancer|Solitary Pulmonary Nodule|Cigarette Smoking Behavior
Interventions: RADIATION: 18F-(2S,4R)4-fluoroglutamine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Strategies: Motivational Interviewing/Psychoeducation
Status: COMPLETED
Conditions: Alcohol Use, Underage|Substance Use|Underage Drinking
Interventions: BEHAVIORAL: Motivational Interviewing|BEHAVIORAL: Psychoeducation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Practicing Alternative Techniques to Heal From Depression: The PATH-D Study
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: BEHAVIORAL: Mindfulness Based Cognitive Therapy|BEHAVIORAL: Health Enhancement Program and medication management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Differences Between Stavudine and Tenofovir Each Combined With Lamivudine and Efavirenz in SA HIV-infected Patients
Status: TERMINATED
Conditions: Mitochondrial Toxicity|Metabolic Complications
Interventions: DRUG: Stavudine|DRUG: Stavudine|DRUG: Tenofovir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Comparative Efficacy and Safety Study of Intermittent Simvastatin and Fenofibrate in Hemodialysis
Status: COMPLETED
Conditions: Fenofibrate/Simvastatin Comparison
Interventions: DRUG: Fenofibrate|DRUG: Simvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of GSK3117391 in Subjects With Rheumatoid Arthritis
Status: TERMINATED
Conditions: Arthritis, Rheumatoid
Interventions: DRUG: GSK3117391|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Benefit of a Single Preoperative Dose of Antibiotics for the Prevention of Surgical Site Infections
Status: COMPLETED
Conditions: Surgical Site Infection
Interventions: DRUG: Amoxicillin/Clavulanic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Release of Osteogenic Markers in Immediately and Non-loaded Dental Implants
Status: COMPLETED
Conditions: Jaw, Edentulous
Interventions: PROCEDURE: Osteogenic markers Evaluation|PROCEDURE: Clinical parameters evaluation|PROCEDURE: Implant instalation|PROCEDURE: Prosthesis installation|PROCEDURE: Suture|DRUG: Post-operative care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Comparison of Pulse Oximetry (SpO2) With Different Oximeters and Arterial Saturation (SaO2): Oxygap2 Study
Status: NOT_YET_RECRUITING
Conditions: Respiratory Failure|Hypoxemia|Hyperoxemia
Interventions: DEVICE: SpO2 and SaO2 comparison
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Rituximab in Patients With Acute ST-elevation Myocardial Infarction Study
Status: COMPLETED
Conditions: Ischemic Heart Disease|Myocardial Infarction|Inflammation
Interventions: DRUG: RiTUXimab Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long-term Tablet-computer Based Casual Puzzle Video Game Intervention in Healthy Older and Cognitively Impaired Persons
Status: COMPLETED
Conditions: Mild Cognitive Impairment|Acquired Brain Injury|Cognitive Impairment|Healthy
Interventions: BEHAVIORAL: Experimental - Puzzle Video Game Intervention|BEHAVIORAL: Control - Tablet Newspaper Reading Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Pharmacokinetic/Pharmacodynamic Drug-drug Interaction of DA-1229 and Metformin After Oral Administration in Healthy Male Subjects
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: DA-1229|DRUG: metformin|DRUG: DA-1229 + metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Three Approaches to Glucose Monitoring in Non-insulin Treated Diabetes
Status: COMPLETED
Conditions: DIABETES MELLITUS, NONINSULIN-DEPENDENT, 2 (Disorder)
Interventions: BEHAVIORAL: SMBG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase IIIb Study of BMS-188667 in Subjects With Active Rheumatoid Arthritis and Inadequate Response to Methotrexate
Status: COMPLETED
Conditions: Active Rheumatoid Arthritis
Interventions: DRUG: Abatacept|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating IMA-026 in Healthy Japanese Males
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: IMA-026
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sensitivity and Reproducibility of 18F-fluorodeoxyglucose Positron Emission Tomography for Assessment of Respiratory Muscle Activity
Status: COMPLETED
Conditions: Respiratory Muscle
Interventions: DIAGNOSTIC_TEST: 18F-FDG Positron emission tomography - MRI|DIAGNOSTIC_TEST: Multiparametric ultrasound imaging|DIAGNOSTIC_TEST: Surface electromyography|DIAGNOSTIC_TEST: Transdiaphragmatic preasure measurmement|DIAGNOSTIC_TEST: Magnetic stimulation of the phrenic nerves|DIAGNOSTIC_TEST: Ventilation against inspiratory loading
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Practice Variation on Antithrombotics in COVID-19
Status: COMPLETED
Conditions: COVID-19 Pneumonia|Thrombosis|COVID-19 Acute Respiratory Distress Syndrome|Severe Acute Respiratory Syndrome (SARS) Pneumonia
Interventions: BEHAVIORAL: Current clinical practices of participating physicians
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy of Omega-3 Fatty Acids on Borderline Personality Disorder
Status: UNKNOWN
Conditions: Borderline Personality Disorder.
Interventions: DRUG: Omacor®|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CB-103 With Either Lenvatinib or Abemaciclib in Patients With NOTCH ACC
Status: RECRUITING
Conditions: Adenoid Cystic Carcinoma|Metastatic Adenoid Cystic Carcinoma|Recurrent Adenoid Cystic Carcinoma
Interventions: DRUG: CB-103|DRUG: Abemaciclib|DRUG: Lenvatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BLADE-PCI Trial (BLADE); PHASE IIB LIPOSOMAL ALENDRONATE STUDY
Status: UNKNOWN
Conditions: Diabetes Mellitus
Interventions: DRUG: LABR-312|DRUG: Saline (placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Transplantation of Bone Marrow Stem Cells Stimulated by Proteins Scaffold to Heal Defects Articular Cartilage of the Knee
Status: UNKNOWN
Conditions: Osteoarthritis|Knee Osteoarthritis|Osteochondritis Dissecans|Osteonecrosis
Interventions: PROCEDURE: Transplantation of Bone Marrow Stem Cells Activated in Knee Arthrosis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Three Supraglottic Airway Devices ProSeal Laryngeal Mask Airway, Air-Q LMA and Ambu AuraGain
Status: COMPLETED
Conditions: Proseal LMA vs Air-Q LMA vs Ambu AurGain LMA
Interventions: DEVICE: Proseal LMA|DEVICE: Air-Q LMA|DEVICE: Ambu AuraGain LMA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Opioid Analgesic Reduction Study (OARS) - Pilot
Status: COMPLETED
Conditions: Post Operative Pain
Interventions: DRUG: OPIOID|DRUG: NON-OPIOID
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Laterally Rotated Flap for Soft Tissue Augmentation Around Maxillary Loaded Osseointegrated Dental Implant
Status: RECRUITING
Conditions: Implant Tissue Failure|Dental Implant Failed|Peri-Implantitis
Interventions: PROCEDURE: soft tissue augmentation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Cannabidiol and Tetrahydrocannabinol on Microbiome and Neuroinflammation in HIV
Status: RECRUITING
Conditions: HIV|Cannabis|THC|Neuroinflammatory Disease|Neuroinflammatory Response|Microbiome
Interventions: DRUG: THC|DRUG: CBD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Low-Fiber Diet or High-Fiber Diet in Preventing Bowel Side Effects in Patients Undergoing Radiation Therapy for Gynecological Cancer, Bladder Cancer, Colorectal Cancer, or Anal Cancer
Status: COMPLETED
Conditions: Anal Cancer|Bladder Cancer|Cervical Cancer|Colorectal Cancer|Fallopian Tube Cancer|Gastrointestinal Complications|Ovarian Cancer|Radiation Toxicity|Sarcoma
Interventions: DIETARY_SUPPLEMENT: dietary intervention|OTHER: laboratory biomarker analysis|PROCEDURE: gastrointestinal complications management/prevention|PROCEDURE: management of therapy complications|RADIATION: selective external radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Cochlear Implantation After Labyrinthectomy or a Translabyrinthine Surgical Approach
Status: COMPLETED
Conditions: Unilateral Acoustic Neuroma|Meniere's Disease
Interventions: DEVICE: Cochlear Implant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Feasibility, Acceptability and Pre Testing the Impact of a Self-management and Tele Monitoring Program for COPD Patients in Lebanon
Status: UNKNOWN
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: BEHAVIORAL: self-management program
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Prospective Study Evaluating a Novel Mobile App Based Preventive Behavioral Intervention for Perinatal Mood Disorders
Status: UNKNOWN
Conditions: Perinatal Depression|Perinatal Anxiety
Interventions: BEHAVIORAL: App-based "positive intelligence" intervention|BEHAVIORAL: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Feasibility and Patient Reported Tolerance of Cryotherapy With the Cooral ® Mouth Cooling Device [MCD) in Patients Undergoing Radiation Therapy
Status: COMPLETED
Conditions: Oral Mucositis
Interventions: DEVICE: Cooral® mouth cooling device (MCD)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: A Study Evaluating the Efficacy and Safety of Inavolisib + Palbociclib + Fulvestrant vs Placebo + Palbociclib + Fulvestrant in Patients With PIK3CA-Mutant, Hormone Receptor-Positive, Her2-Negative, Locally Advanced or Metastatic Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Inavolisib|DRUG: Placebo|DRUG: Palbociclib|DRUG: Fulvestrant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Presessions for the National Diabetes Prevention Program
Status: ACTIVE_NOT_RECRUITING
Conditions: Prediabetic State|Obesity|Gestational Diabetes
Interventions: BEHAVIORAL: Presessions|BEHAVIORAL: National Diabetes Prevention Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Personalized Infliximab Induction Strategy With Model-informed Dosing in Patients With Crohn's Disease
Status: RECRUITING
Conditions: Crohn Disease
Interventions: DEVICE: RoadMAB|DRUG: Precision dosing with a dashboard
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study of ARRY-371797 in Patients With Active Ankylosing Spondylitis
Status: TERMINATED
Conditions: Ankylosing Spondylitis
Interventions: DRUG: ARRY-371797, p38 inhibitor; oral|DRUG: Placebo; oral|DRUG: Placebo; oral
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effect of Botulinum Toxin Type-A Injection Prior to Surgical Correction of Complete Unilateral Cleft Lip Repair by Modified Millard Cheiloplasty
Status: UNKNOWN
Conditions: Esthetic Outcome of Injection of Botulinum Toxin Type-A in Cleft Lip Repair
Interventions: DRUG: Botulinum toxin type A
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Cannabis Edibles Packaging Descriptors Experiment
Status: COMPLETED
Conditions: Cannabis Use
Interventions: BEHAVIORAL: "All Natural" descriptor|BEHAVIORAL: "Gluten-free" descriptor|BEHAVIORAL: "Vegan" descriptor|BEHAVIORAL: "100% Organic" descriptor|BEHAVIORAL: "Handcrafted" descriptor|BEHAVIORAL: "Made with live resin" descriptor|BEHAVIORAL: "Fast-acting" descriptor|BEHAVIORAL: "Relax" descriptor|BEHAVIORAL: "Energy Boost" descriptor|BEHAVIORAL: No descriptor (control)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Semaglutide vs Metformin in Polycystic Ovary Syndrome (PCOS)
Status: NOT_YET_RECRUITING
Conditions: Polycystic Ovary Syndrome
Interventions: DRUG: Metformin|DRUG: Semaglutide Injectable Product
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EVOLVE II QCA: A Prospective, Multicenter Trial to Assess the SYNERGY Stent System for the Treatment of Atherosclerotic Lesion(s)
Status: COMPLETED
Conditions: Atherosclerotic Lesion(s)
Interventions: DEVICE: SYNERGY
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BURT Efficacy in Improving Upper Extremity Strength and Function During Post-stroke Inpatient Rehabilitation
Status: RECRUITING
Conditions: Stroke|Stroke, Acute|Cerebral Vascular Accident|Cerebral Vascular Accident (CVA)/Stroke
Interventions: DEVICE: BURT|PROCEDURE: Other Occupational Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Longitudinal, Multi-Dimensional Assessment of Recovery and Added Benefit of a Behavioral Health Intervention for Children With Abusive Head Trauma
Status: COMPLETED
Conditions: Non-Accidental Traumatic Head Injury to Child
Interventions: BEHAVIORAL: Attachment and Biobehavioral Catch-up (ABC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of a Peroxisome Proliferator-activated Receptor (PPAR) Alpha Agonist on Cytochrome P450 (CYP) Monooxygenase Activity in Humans
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: fenofibrate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Does Memantine Improve Verbal Memory Task Performance in Subjects With Partial Epilepsy and Memory Dysfunction?
Status: COMPLETED
Conditions: Epilepsy
Interventions: DRUG: Memantine|OTHER: Sugar Pill|DRUG: Memantine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Corrected VA With Long-Term Follow-Up After AcrySof® Intraocular Lens (IOL) Implantation
Status: COMPLETED
Conditions: Pseudophakia
Interventions: DEVICE: Acrylic IOL|DEVICE: Silicone IOL|DEVICE: PMMA IOL
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Study of Pegilodecakin (LY3500518) With Pembrolizumab Compared to Pembrolizumab Alone First-line Tx in Participants With Metastatic Non-Small Cell Lung Cancer
Status: TERMINATED
Conditions: Non Small Cell Lung Cancer
Interventions: BIOLOGICAL: Pegilodecakin|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lifestyle Modification Intervention for Obese Children
Status: COMPLETED
Conditions: Childhood Obesity|Life Style Modification
Interventions: BEHAVIORAL: Stage-based Lifestyle Modification Intervention for the Management of Childhood Obesity|BEHAVIORAL: Existing practice for the management of childhood obesity
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Significance of Subclinical Myocardial Involvement in Recovered COVID-19 Patients Using Cardiovascular Magnetic Resonance (R-COVID-CMR)
Status: RECRUITING
Conditions: Covid19|Viral Respiratory Infection
Interventions: DIAGNOSTIC_TEST: Cardiac Magnetic Resonance Imaging (CMR)|DIAGNOSTIC_TEST: Blood test|DIAGNOSTIC_TEST: 6-minute walk test
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Dose Escalation Study to Assess the Safety and Tolerability of Genz-644282 in Patients With Solid Tumors
Status: COMPLETED
Conditions: Solid Tumors
Interventions: DRUG: Genz-644282 (28-day dosing schedule)|DRUG: Genz-644282 (21-day dosing schedule)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of SGN-40 in Combination With Rituximab in Patients With CD20-Positive, Follicular and Marginal Zone B-Cell Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Non-Hodgkin's Lymphoma
Interventions: DRUG: rituximab|DRUG: SGN-40
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of MabThera (Rituximab) in Primary Central Nervous System Lymphoma.
Status: TERMINATED
Conditions: Lymphoma
Interventions: DRUG: rituximab [MabThera/Rituxan]|DRUG: Methotrexate|DRUG: Cytarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Influence of Dietary Variety and Course Sequence on Fruit Intake in Preschool-Aged Children
Status: COMPLETED
Conditions: Caloric Intake
Interventions: BEHAVIORAL: Variety|BEHAVIORAL: Non-Variety
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Adapting and Testing a Behavioural Intervention to Prevent FASD and Adverse Infant Outcomes
Status: RECRUITING
Conditions: Maternal Behavior|Alcohol Drinking|Fetal Conditions
Interventions: BEHAVIORAL: Intervention with contingent incentives and text-based support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Radiographic and Inflammatory Biomarker Changes in Chronic Low Back Pain
Status: COMPLETED
Conditions: Low Back Pain
Interventions: DEVICE: Isokinetic training|DEVICE: Virtual reality training|OTHER: Exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Yield of Endoscopic Ultrasound Guided Fine Needle Aspiration (EUS-FNA) With and Without the Use of a Stylet in the Biopsy Needle
Status: COMPLETED
Conditions: Pancreatic Mass on Imaging
Interventions: PROCEDURE: Endoscopic ultrasound guided fine needle aspiration biopsy|PROCEDURE: Stylet out FNA first, Stylet in FNA second
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety and Efficacy of AGN-210961 Ophthalmic Solution Compared With Bimatoprost Ophthalmic Solution in Patients With Glaucoma or Ocular Hypertension
Status: COMPLETED
Conditions: Ocular Hypertension|Primary Open-Angle Glaucoma
Interventions: DRUG: AGN-210961 Formulation 1|DRUG: AGN-210961 Formulation 2|DRUG: AGN-210961 Formulation 3|DRUG: AGN-210961 Formulation 4|DRUG: AGN-210961 Formulation 5|DRUG: AGN-210961 Formulation 6|DRUG: AGN-210961 Formulation 7|DRUG: bimatoprost ophthalmic solution 0.03%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Transcutaneous Stimulation on Blood Pressure in Spinal Cord Injury (SCI)
Status: RECRUITING
Conditions: Spinal Cord Injuries|Hypotension|Orthostatic Hypotension|Spinal Cord Diseases|Cardiovascular Diseases|Trauma, Nervous System|Central Nervous System Diseases|Nervous System Diseases|Blood Pressure
Interventions: DEVICE: Biostim-5 transcutaneous spinal stimulator|DIAGNOSTIC_TEST: Tilt-table orthostatic stress testing
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate CNTO 1959 in the Treatment of Patients With Moderate to Severe Plaque-type Psoriasis
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: CNTO 1959 (5 mg)|DRUG: CNTO 1959 (15 mg)|DRUG: CNTO 1959 (50 mg)|DRUG: CNTO 1959 (100 mg)|DRUG: CNTO 1959 (200 mg)|DRUG: Adalimumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Implementing the Modified A-DIVA Scale on Successful Access to a Venous Line on the First Attempt
Status: RECRUITING
Conditions: Chronic Disease
Interventions: PROCEDURE: Training in the A-DIVA scale and its failure prediction score
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Comparison of Extensible and Inextensible Lumbosacral Orthoses for Lower Back Pain
Status: COMPLETED
Conditions: Low Back Pain
Interventions: OTHER: Inextensible LSO (stiff back support)|OTHER: Extensible LSO, a back support that is flexible|OTHER: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Learning and Encouragement Effect on 6 Minute Walking Test in Children Between 6 and 12 Years
Status: COMPLETED
Conditions: Healthy Children
Interventions: OTHER: six minute walking test|OTHER: six minute walking test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Mindfulness-Based Relapse Prevention Program on Readiness for Change and Self-efficacy Among Clients With Substance Use Disorders
Status: COMPLETED
Conditions: Substance Use Disorders
Interventions: BEHAVIORAL: Mindfulness-Based Relapse Prevention program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Dexmedetomidine Infusion Dose Versus Rapid Bolus Dose Before Tracheal Intubation.
Status: RECRUITING
Conditions: Dexmedetomidine|Intubation Complication
Interventions: DRUG: Dexmedetomidine infusion|DRUG: Dexmedetomidine bolus|DRUG: Atropine Sulfate|DRUG: Ephedrine|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phase II Trial of Combination Therapy With Bevacizumab and S-1 in Elderly Patients With Unresectable or Recurrent Colorectal Cancer (BASIC)
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: S-1, Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Emulation of the KEYNOTE-189 Trial Using Electronic Health Records
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer|Metastatic Lung Cancer
Interventions: DRUG: Pembrolizumab + Pemetrexed-Platinum|DRUG: Pemetrexed-Platinum
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Tolerability of Nebicapone in Parkinson's Disease Patients With "Wearingoff" Phenomenon
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: DRUG: Comtan®|DRUG: Nebicapone|DRUG: Levodopa/DDCI|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Postoperative Experience of 2 WALANT-type Modes of Anesthesia Used in Ambulatory Surgery of the Upper Limb.
Status: COMPLETED
Conditions: Anesthesia, Local|Hand Surgery|Wrist Surgery|Elbow Surgery
Interventions: COMBINATION_PRODUCT: Ambulatory surgery under Lidocaine alone|COMBINATION_PRODUCT: Ambulatory surgery under a combination of Lidocaine and Ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study on the Effect of Renal Impairment on the Pharmacokinetics of RO4917838
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: RO4917838|DRUG: RO4917838
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Study on Akin Osteotomy: Fixation Versus Non-fixation (Fixakin)
Status: UNKNOWN
Conditions: Akin Osteotomy|Hallux Valgus
Interventions: PROCEDURE: AKIN osteotomy with screw fixation|PROCEDURE: AKIN osteotomy without screw fixation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Crossmodal Learning in Therapeutic Processes (Task 2-1)
Status: SUSPENDED
Conditions: Stroke
Interventions: DEVICE: Vibro-tactile stimulation|OTHER: Placebo Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bone Mineral Density and Periodontal Status in Patients on Antiepileptic Drug
Status: UNKNOWN
Conditions: Alveolar Bone Loss
Interventions: OTHER: effect of sodium valproate on alveolar bone level|OTHER: effect of levetiracetam on alveolar bone level|OTHER: effect of sodium valproate+levetiracetam on alveolar bone level|OTHER: control group
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Rituximab Combined With Prior Therapy in Advanced Hepatocellular Carcinoma: Efficacy & Safety Study
Status: NOT_YET_RECRUITING
Conditions: Advanced Hepatocellular Carcinoma
Interventions: DRUG: Rituximab+PD-1 or PD-L1 inhibitors+targeted therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to the Assess the Change in Condition and Adverse Events of OnabotulinumtoxinA X Injection in Adult Participants With Glabellar Lines
Status: COMPLETED
Conditions: Glabellar Lines
Interventions: DRUG: OnabotulinumtoxinA X|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CAT BITE Antibiotic Prophylaxis for the Hand/Forearm (CATBITE)
Status: RECRUITING
Conditions: Cat Bite|Hand Injuries|Arm Injury|Infection, Bacterial|Anti-bacterial Agents
Interventions: DRUG: Amoxicillin/clavulanate|DRUG: Ciprofloxacin|DRUG: Clindamycin|OTHER: Placebo (microcrystalline cellulose)|PROCEDURE: Wound management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Are Postoperative Patient PROMS Influenced by Recall of Preoperative Scores?
Status: COMPLETED
Conditions: Degenerative Diseases, Spinal Cord
Interventions: BEHAVIORAL: PROMs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study Using Hyperpolarized 13C-Pyruvate Magnetic Resonance Spectroscopic Imaging in Patients With Pancreatic Cysts Undergoing Surgical Resection
Status: RECRUITING
Conditions: Pancreatic Cyst
Interventions: DRUG: Hyperpolarized 13-C-pyruvate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Diastolic RV EvAluation With Millar Catheter to Investigate the Effect of Glucagon-Like Peptide-1 (GLP-1) on Right Ventricular Function During Elective Coronary Angioplasty and Stenting
Status: UNKNOWN
Conditions: Right Coronary Artery Percutaneous Coronary Intervention|Right Ventricular Diastolic Dysfunction
Interventions: PROCEDURE: Right Coronary Artery Percutaneous Coronary Intervention|OTHER: saline placebo infusion|OTHER: GLP-1 Infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Intravenous Acetaminophen During Perioperative Neurosurgery Period
Status: COMPLETED
Conditions: Craniotomy|Brain Surgery
Interventions: DRUG: Acetaminophen|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: To Assess Efficacy and Safety of Batoclimab in Adult Participants With Active CIDP
Status: RECRUITING
Conditions: Chronic Inflammatory Demyelinating Polyneuropathy
Interventions: DRUG: Batoclimab 680 milligrams (mg) subcutaneous (SC) weekly|DRUG: Batoclimab 340 mg SC weekly|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: TRANscatheter or SurgIcal Aortic Valve ReplacemenT in All-Comers With Severe Aortic Valve Stenosis
Status: WITHDRAWN
Conditions: Aortic Valve Stenosis
Interventions: DEVICE: SAPIEN 3|PROCEDURE: SAVR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Treadmill Training With Visual and Auditory Cues on Gait Parameters in Parkinsonian Patients in Advanced Stages of Disease.
Status: UNKNOWN
Conditions: Parkinson Disease
Interventions: PROCEDURE: treadmill training with cues
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Benefit of Chemotherapy Over Best Supportive Care in Metastatic and Squamous Cell-type Esophageal Cancer.
Status: TERMINATED
Conditions: Squamous Cell Carcinoma of Esophagus
Interventions: DRUG: FU-CDDP|DRUG: LV5FU2-CDDP|DRUG: FOLFOX|DRUG: TPF|OTHER: Best Supportive Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparison of SCH 56592 and Fluconazole in the Treatment of Oropharyngeal Candidiasis (OPC) in HIV-Positive Patients
Status: COMPLETED
Conditions: Candidiasis, Oral|HIV Infections
Interventions: DRUG: Posaconazole|DRUG: Fluconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety, Tolerability and Immunogenicity of EGFR(V)-EDV-Dox in Subjects With Recurrent Glioblastoma Multiforme (GBM)
Status: UNKNOWN
Conditions: Glioblastoma|Astrocytoma, Grade IV
Interventions: DRUG: EGFR(V)-EDV-Dox
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of the Efficacy and Safety of Pembrolizumab for Ovarian Squamous Cell Carcinoma
Status: RECRUITING
Conditions: Ovarian Squamous Cell Carcinoma
Interventions: DRUG: MK-3475 (pembrolizumab)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics of Asacol 2.4 g/Day and Lialda 2.4 g/Day in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Asacol|DRUG: Asacol|DRUG: Lialda
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Cardiovascular Protective Role of Laser Acupuncture in Systemic Lupus
Status: COMPLETED
Conditions: System; Lupus Erythematosus
Interventions: DEVICE: laser application on acupoints
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Neurofeedback for Nociplastic Pain in Rheumatoid Arthritis (NECTAR)
Status: NOT_YET_RECRUITING
Conditions: Rheumatoid Arthritis|Chronic Widespread Pain
Interventions: PROCEDURE: Neurofeedback
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Visual and Auditory Feedback on Eye-hand Coordination in Children With Hemiplegic Cerebral Palsy
Status: UNKNOWN
Conditions: Hemiplegic Cerebral Palsy
Interventions: PROCEDURE: physical therapy program|DEVICE: E-Link Upper Limb Exerciser|COMBINATION_PRODUCT: physical therapy program and ELink Upper Limb Exerciser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Long Term Follow-up Study to Assess Durability of Sustained Virologic Response in Alisporivir-treated Hepatitis C Patients
Status: COMPLETED
Conditions: Hepatitis C
Interventions: DRUG: Alisporivir
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Concurrent Chemoradiotherapy for Cervical Cancer in Elderly Women
Status: UNKNOWN
Conditions: Cervical Cancer
Interventions: RADIATION: irradiation|DRUG: Cisplatin|DRUG: liposome paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Determination of Optimum Duration of Treatment With Bromfenac (Xibrom) Eyedrops Following Cataract Surgery
Status: COMPLETED
Conditions: Cataracts
Interventions: DRUG: Bromfenac|DRUG: Moxifloxacin hydrochloride|DRUG: Prednisolone Acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Efficacy of Ombitasvir/Paritaprevir/r With or Without Dasabuvir and With or Without Ribavirin in Chronic Hepatitis C Virus Genotype 1 or 4 Infected Adults With Successfully Treated Early Stage Hepatocellular Carcinoma
Status: TERMINATED
Conditions: Chronic Hepatitis C Infection
Interventions: DRUG: ombitasvir/paritaprevir/ritonavir and dasabuvir|DRUG: ombitasvir/paritaprevir/ritonavir|DRUG: ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Donor-Derived Anti-CD33 CAR T Cell Therapy (VCAR33) in Patients With Relapsed or Refractory AML After Allogeneic Hematopoietic Cell Transplant
Status: RECRUITING
Conditions: Leukemia, Myeloid, Acute
Interventions: BIOLOGICAL: VCAR33
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intraoperative Local Anaesthetic and Postoperative Pain
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: PROCEDURE: Wound infiltration with local anaesthetic|DRUG: Ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Open Versus Laparoscopic Radical Cystectomy
Status: UNKNOWN
Conditions: Bladder Cancer
Interventions: PROCEDURE: Laparoscopic radical cystectomy with open urinary diversion|PROCEDURE: Open radical cystectomy with open urinary diversion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Trial of Atorvastatin on the Persistent Coronary Aneurysm in Children With Kawasaki Disease
Status: UNKNOWN
Conditions: Kawasaki Disease|Aneurysm, Coronary
Interventions: DRUG: Atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Study in Adults Sensitized to Cat
Status: COMPLETED
Conditions: Allergy
Interventions: BIOLOGICAL: Standardized Allergenic Extract, Cat Hair|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of eRapa to Prevent Progression in Familial Adenomatous Polyposis Patients Under Active Surveillance
Status: RECRUITING
Conditions: Familial Adenomatous Polyposis
Interventions: DRUG: Encapsulated Rapamycin (eRapa)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Satiety, Glycemic, and Gastrointestinal Effects of Novel Fibers
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: Resistant Starch|DIETARY_SUPPLEMENT: Resistant starch + soluble fiber|DIETARY_SUPPLEMENT: Fiber made from corn starch|DIETARY_SUPPLEMENT: Fiber made from corn starch + soluble fiber
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Cough Suppressive Therapy in Patients With Chronic Cough
Status: RECRUITING
Conditions: Chronic Cough
Interventions: BEHAVIORAL: Cough suppressive therapy|BEHAVIORAL: General healthy lifestyle instructions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Botulinum Toxin in the Treatment of Raynaud's
Status: COMPLETED
Conditions: Raynaud's Syndrome
Interventions: DRUG: botulinum toxin A
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: RCT on the Efficacy of Methotrexate for the Prevention of GTD
Status: COMPLETED
Conditions: Hydatidiform Mole
Interventions: DRUG: Methotrexate|DRUG: Vitamin B Complex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Hartmann's Solution and Normal Saline in Type II Diabetes Patients
Status: WITHDRAWN
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Hartmann's solution|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Determine the Efficacy of TT-173. Reducing the the Total Blood Loss Associated With Total Knee Arthroplasty (HESTAT)
Status: UNKNOWN
Conditions: Degenerative Osteoarthritis
Interventions: OTHER: placebo|BIOLOGICAL: TT-173
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety of Repeat Intravitreal Injection of Human Retinal Progenitor Cells (jCell) in Adult Subjects With Retinitis Pigmentosa
Status: COMPLETED
Conditions: Retinitis Pigmentosa
Interventions: BIOLOGICAL: human retinal progenitor cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Safety and Efficacy of PET-adapted Treatment With Nivolumab at the Fixed Dose 40 mg, Ifosfamide, Carboplatin, Etoposide (NICE-40) in Patients With Relapsed/Refractory Hodgkin Lymphoma
Status: RECRUITING
Conditions: Hodgkin Lymphoma
Interventions: DRUG: Nivolumab|DRUG: Ifosfamide|DRUG: Carboplatin|DRUG: Etoposide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rituximab for the Treatment of Severe Ocular Manifestations of Behcet's Disease
Status: COMPLETED
Conditions: Behcet's Syndrome
Interventions: DRUG: Rituximab|DRUG: Cytotoxic Combination
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of INCB099280 in Participants With Advanced Solid Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Solid Tumor|MSI-H/dMMR Tumors|Cutaneous Squamous Cell Carcinoma|Urothelial Carcinoma|Cervical Cancer|HepatoCellular Carcinoma|Esophageal Squamous Cell Carcinoma|Merkel Cell Carcinoma|Small-cell Lung Cancer|Mesothelioma|PD-L1 Amplified Tumor (9p24.1)|Nasopharyngeal Carcinoma
Interventions: DRUG: INCB099280
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Trial of HY209gel in Atopic Dermatitis Patients
Status: RECRUITING
Conditions: Atopic Dermatitis|Atopic Dermatitis Eczema|Atopic Dermatitis of Scalp
Interventions: DRUG: HY209GEL Active|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT