pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Endotoxins and Cytokines Removal During Continuous Hemofiltration With oXiris™
Status: COMPLETED
Conditions: Septic Shock|Peritonitis
Interventions: BIOLOGICAL: Arterial blood sampling|BIOLOGICAL: Ultrafiltrate sampling|DEVICE: CVVH using oXiris™ filter|DEVICE: CVVH using PrismafleX HF1400 filter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effects of Fluid Infusion on Postoperative Vomiting in Pediatric Patients Undergoing Otorhinolaryngological Surgery
Status: COMPLETED
Conditions: Postoperative Nausea and Vomiting
Interventions: DRUG: %0.9 NaCl 10ml/kg|DRUG: %0.9 NaCl 20ml/kg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Laparoscopic Versus Open Liver Resection for Hepatocellular Carcinoma
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma
Interventions: PROCEDURE: laparoscopic hepatectomy|PROCEDURE: Open hepatectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Anti-fibrotic Therapeutic Effects of Resveratrol for Discharged COVID-19 Patients
Status: UNKNOWN
Conditions: Covid-19
Interventions: DRUG: Resveratrol|DRUG: Placebo capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Obeldesivir in Participants With COVID-19 Who Have a High Risk of Developing Serious or Severe Illness
Status: TERMINATED
Conditions: COVID-19
Interventions: DRUG: Obeldesivir|DRUG: Obeldesivir Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment for Sleep Disturbance in Orthopaedic Trauma Patients
Status: COMPLETED
Conditions: Sleep Disturbance|Trauma
Interventions: DIETARY_SUPPLEMENT: Melatonin 5mg and Sleep Education|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: CLINICAL TRIAL PHASE II, MULTICENTRIC, NATIONAL, DOUBLE-BLIND, PARALLEL, RANDOMIZED, AND PLACEBO-CONTROLLED FOR EVALUATION OF THE IMPROVEMENT OF SLEEP QUALITY IN PARTICIPANTS OF RESEARCH WITH INSOMNIA DISORDER
Status: NO_LONGER_AVAILABLE
Conditions: Sleep Initiation and Maintenance Disorders
Interventions: DRUG: QUALI
Study Type: EXPANDED_ACCESS
Clinical trial: Combination of Nelmastobart and Capecitabine Therapy in Metastatic Colorectal Cancer
Status: NOT_YET_RECRUITING
Conditions: Recurrent or Metastatic Colorectal Cancer
Interventions: DRUG: Nelmastobart and Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Study of FG-3019 in Subjects With Type 1 or Type 2 Diabetes Mellitus and Diabetic Nephropathy
Status: COMPLETED
Conditions: Diabetes Mellitus|Diabetic Nephropathy
Interventions: DRUG: FG-3019|DRUG: FG-3019|DRUG: FG-3019
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Mindfulness Meditation (MBSR) and Parkinson's Disease (PD)
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: BEHAVIORAL: Mindfulness-Based Stress Reduction-based program (MBSR).
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Relation Between Common Carotid Artery Diameter and Central Venous Pressure for Assessment of Intravascular Fluid Status After Major Surgeries: An Observational Study
Status: UNKNOWN
Conditions: Fluid Resuscitation Monitoring Non-invasively
Interventions: DIAGNOSTIC_TEST: common carotid artery diameter measurement
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Digital Cognitive Behavioral Therapy for Depressive Disorders
Status: RECRUITING
Conditions: Depression|Anxiety
Interventions: BEHAVIORAL: Digital Cognitive Behavioral Therapy|BEHAVIORAL: Health Education|DRUG: TAU
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Modified T'ai Chi on Symptoms in Older Adults With Osteoarthritis
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: BEHAVIORAL: Modified T'ai Chi: T'ai Chi for Arthritis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Stability of Implants With Two Different Surface Treatments
Status: COMPLETED
Conditions: Dental Implant Failed|Pre-osseointegration Failure of Dental Implant
Interventions: PROCEDURE: Implant surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of Crenolanib With Fludarabine and Cytarabine in Pediatric Patients With Relapsed/Refractory FLT3-Mutated Acute Myeloid Leukemia
Status: WITHDRAWN
Conditions: Relapsed/Refractory FLT3-mutated AML
Interventions: DRUG: Crenolanib|DRUG: Fludarabine|DRUG: Cytarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Faecal Microbiota Transplantation (FMT) in Patients With IBSmechanism(s) of Action
Status: COMPLETED
Conditions: Irritable Bowel Syndrome
Interventions: DIETARY_SUPPLEMENT: Feces
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Zinc Supplementation With Topical Retinoids in Acne Vulgaris Patients
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DIETARY_SUPPLEMENT: Zinc sulphate tablet 20 mg|DIETARY_SUPPLEMENT: Placebo tablet 20 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Carbetocin at Cesarean Delivery for Labor Arrest
Status: COMPLETED
Conditions: Postpartum Hemorrhage
Interventions: DRUG: Carbetocin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: FactOr XIa inhibiTion for the pRevention of venOus Thromboembolism in Patients Undergoing Total Knee Arthroplasty
Status: COMPLETED
Conditions: Knee Arthroplasty, Total
Interventions: DRUG: Enoxaparin|DRUG: Apixaban|DRUG: BAY1213790
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Phase I Dose-Escalation Study Of Azacitidine In Combination With Temozolomide
Status: UNKNOWN
Conditions: Soft Tissue Sarcoma|Mesothelioma
Interventions: DRUG: Azacitidine In Combination With Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of 2 Formulations of Tuberculosis Vaccine GSK692342 Given at 0,1 Months to Healthy Adults
Status: COMPLETED
Conditions: Tuberculosis
Interventions: BIOLOGICAL: GSK's candidate Mycobacterium tuberculosis vaccine 692342|BIOLOGICAL: Comparator vaccine with recombinant Mycobacterium tuberculosis antigen and adjuvant system|BIOLOGICAL: Comparator vaccine with recombinant Mycobacterium tuberculosis antigen and physiological saline|BIOLOGICAL: Control vaccine with the adjuvant system.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Use of 5-aminolevulinic Acid (ALA) as an Intraoperative Tumor Marker for Resection of Pediatric Central Nervous System (CNS) Tumors
Status: UNKNOWN
Conditions: Central Nervous System Tumor, Pediatric
Interventions: DRUG: 5ALA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gene Therapy Clinical Trial for the Treatment Of Leber's HereDitary Optic Neuropathy
Status: RECRUITING
Conditions: Leber's Hereditary Optic Neuropathy (LHON)
Interventions: DRUG: NR082 injection|DEVICE: Sham Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vitamin D in Armenia: Vitamin D Repletion Strategies With Dibase, and Vitamin D and Vitamin D Binding Protein and COVID
Status: ACTIVE_NOT_RECRUITING
Conditions: Vitamin D Deficiency
Interventions: DIETARY_SUPPLEMENT: Vitamin D3 (Cholecalciferol)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Retrograde Intrarenal Stone Surgery - A Method of Treating the ESWL Resistant Kidney Stone
Status: UNKNOWN
Conditions: Kidney Stone|Ureteroscopy
Interventions: DRUG: Isoproterenol
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study on Exploring the Effect of DPP-4 Inhibitors on β-cell Function by Using the Two-step Hyperglycemic Clamp
Status: UNKNOWN
Conditions: Type 2 Diabetes
Interventions: DRUG: Sitagliptin|DRUG: Saxagliptin|DRUG: Blank control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: FR901228 Alone or Combined With Rituximab and Fludarabine in Treating Patients With Relapsed or Refractory Low-Grade B-Cell Non-Hodgkin's Lymphoma
Status: TERMINATED
Conditions: Recurrent Grade 1 Follicular Lymphoma|Recurrent Grade 2 Follicular Lymphoma|Recurrent Small Lymphocytic Lymphoma
Interventions: DRUG: romidepsin|BIOLOGICAL: rituximab|DRUG: fludarabine phosphate|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 2b Diabetic Kidney Disease Study
Status: COMPLETED
Conditions: Diabetic Kidney Disease
Interventions: DRUG: MEDI3506|DRUG: Placebo|DRUG: Dapagliflozin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Progression of Renal Interstitial Fibrosis / Tubular Atrophy (IF/TA) According to Epithelial-mesenchymal Transition (EMT) and Immunosuppressive Regimen (Everolimus Based Versus CNI Based) in de Novo Renal Transplant Recipients
Status: COMPLETED
Conditions: Renal Interstitial Fibrosis
Interventions: DRUG: Certican®|DRUG: Neoral|DRUG: Myfortic|DRUG: Simulect®|DRUG: Corticosteroids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevention of Falls and Fractures in Old People by Administration of Calcium and Vitamin D. Randomized Clinical Trial
Status: UNKNOWN
Conditions: Fall|Fractures
Interventions: DRUG: Vitamin D and calcium suplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Trial of Vitamins in HIV Progression and Transmission
Status: COMPLETED
Conditions: HIV Infections|Disease Transmission, Vertical
Interventions: DIETARY_SUPPLEMENT: Vitamin A + Beta Carotene|DIETARY_SUPPLEMENT: Multivitamins|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of NovoFine® Needles (4 mm vs. 6 mm)
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 1|Diabetes Mellitus, Type 2|Delivery Systems
Interventions: DEVICE: NovoFine® needle 6 mm|DEVICE: NovoFine® needle 4 mm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Insertion Time Over Fiberoptic Bronchoscope of Double Lumen Tube and Single Lumen Tube
Status: COMPLETED
Conditions: Intubation;Difficult
Interventions: DEVICE: single lumen tube and bronchial blocker|DEVICE: double lumen tube
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: A Study of T-VEC (Talimogene Laherparepvec) With or Without Radiotherapy for Melanoma, Merkel Cell Carcinoma, or Other Solid Tumors
Status: COMPLETED
Conditions: Melanoma|Merkel Cell Carcinoma|Other Solid Tumors
Interventions: DRUG: TALIMOGENE LAHERPAREPVEC (TVEC)|RADIATION: Hypofractionated Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial to Reduce Skin Burn Induced by Breast Radiotherapy Using Intensity Modulated Radiation Therapy (IMRT)
Status: COMPLETED
Conditions: Breast Neoplasms
Interventions: DEVICE: Breast IMRT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study on the First-line Treatment of Advanced Biliary System Tumors With Tripley Monoclonal Antibody Combined With GEMOX Regimen
Status: UNKNOWN
Conditions: Advanced Biliary Tract Tumors
Interventions: DRUG: Toripalimab injection combined with GEMOX
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endodrill vs. Conventional Biopsy. Evaluation of Diagnostic Capacity in Diffuse Gastric Cancer
Status: WITHDRAWN
Conditions: Stomach Neoplasms
Interventions: DEVICE: Boston Scientific Large Capacity with needle Biopsy|DEVICE: Endodrill 1A (BIBBInstruments, Lund, Sweden)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effects of Polyunsaturated Fatty Acids on Intestinal Lipid Metabolism in Insulin-resistant Men
Status: COMPLETED
Conditions: Metabolic Syndrome
Interventions: OTHER: Polyunsaturated fatty acids diet|OTHER: Saturated fatty acids diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Plant-Based, American Heart Assoc. or Mediterranean Diets In 9-18 yo With BMI >95%, Cholesterol >169 and Their Parents
Status: COMPLETED
Conditions: Obesity|Hypercholesterolemia|Cardiovascular Disease
Interventions: OTHER: Plant-Based Diet|OTHER: American Heart Association Diet|OTHER: Mediterranean Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Plasma microRNA Levels and Some Cytokines Expression in Patients With ITP Primary Immune Thrombocytopenic Purpura (ITP)
Status: RECRUITING
Conditions: Primary Immune Thrombocytopenia
Interventions: DIAGNOSTIC_TEST: Plasma RNA isolation, qPCR analysis of micro RNA|DIAGNOSTIC_TEST: estimation of serum level of IL2|DIAGNOSTIC_TEST: estimation of serum level of IL17
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Alisporivir With RBV in Chronic Hepatitis C Genotype 2 and 3 Participants for Whom Interferon is Not an Option
Status: COMPLETED
Conditions: Hepatitis C|Liver Disease
Interventions: DRUG: Alisporivir|DRUG: Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Ventilation Modes on Cerebral Oxymetry In Operation
Status: COMPLETED
Conditions: Cholecystitis; Gallstone|Mechanical Ventilation Pressure High|Intraabdominal Hypertension
Interventions: DEVICE: mechanical ventilation modes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: A Study to Access the Safety/Efficacy of Thalidomide in the Treatment of Anemia in Patients With Myelodysplastic Syndromes
Status: COMPLETED
Conditions: Myelodysplastic Syndromes
Interventions: DRUG: thalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Instrument Assisted Soft Tissue Mobilization and Myofascial Gun in Upper Cross Syndrome
Status: COMPLETED
Conditions: Postural; Defect
Interventions: OTHER: Myofascial gun with conventional therapy|OTHER: Instrument Assisted Soft Tissue Mobilization with Conventional therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Experience of Use and Biopsychosocial Effects of Robotic and Virtual Reality Devices in Neuromotor Rehabilitation
Status: COMPLETED
Conditions: Neurologic Diseases|Arthropathy of Knee|Arthropathy of Hip
Interventions: OTHER: Multidisciplinary Conventional Neuromotor Rehabilitation|DEVICE: Technology-based Rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Allogeneic Mixed Chimerism Stem Cell Transplant Using Campath for Hemoglobinopathies & Bone Marrow Failure Syndromes
Status: COMPLETED
Conditions: Sickle Cell Anemia|Severe Aplastic Anemia|Paroxysmal Nocturnal Hemoglobinuria (PNH)|Pure Red Cell Aplasia
Interventions: DRUG: Campath, Chemo and/or TBI Allo SCT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pemf Therapy for the Management of Diabetes in Obese Patients
Status: UNKNOWN
Conditions: Obesity|Type 2 Diabetes
Interventions: DEVICE: Pulsed Electromagnetic Fields|DEVICE: Sham Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of CM310 in Subjects With Chronic Pruritus
Status: UNKNOWN
Conditions: Chronic Pruritus of Unknown Origin
Interventions: BIOLOGICAL: CM310
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A First in Human Study to Evaluate the Safety of Infusion of MNV-BM-PLC (Autologous CD34+ Cells Enriched With Placenta Derived Allogeneic Mitochondria) in Patients With Primary Mitochondrial Diseases Associated With Mitochondrial DNA Mutation or Deletion
Status: UNKNOWN
Conditions: Primary Mitochondrial Diseases
Interventions: PROCEDURE: Bone Marrow mobilization|PROCEDURE: Apheresis|BIOLOGICAL: MNV-BM-PLC infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of a New Plant-based High-energy Oral Nutritional Supplement on Nutritional Outcomes in Malnourished Patients
Status: RECRUITING
Conditions: Malnutrition|Cancer|Inflammatory Bowel Diseases|Chronic Obstructive Pulmonary Disease (COPD)|Hiv
Interventions: DIETARY_SUPPLEMENT: Fortimel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Repetitive Transcranial Magnetic Stimulation as Treatment for Acute Suicidality in Adult Patients
Status: TERMINATED
Conditions: Suicidal Ideation
Interventions: DEVICE: repetitive transcranial magnetic stimulation (rTMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Convenience and Safety of Assisted Reproductive Technology Procedures Using a Gonal-F Filled by Mass (Fbm) Liquid Formulation Applied by Pen for Ovulation Induction and In-vitro Fertilization
Status: COMPLETED
Conditions: Infertility|Ovulation Induction|In-Vitro Fertilization
Interventions: DRUG: GONAL-f®
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Functional Image-Guided Carbon Ion Irradiation With Simultaneous Integrated Boost for Prostate Cancer
Status: RECRUITING
Conditions: Localized Prostate Cancer
Interventions: RADIATION: carbon ion irradation|RADIATION: Carbon Ion Irradiation With SIB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Idelalisib (GS-1101, CAL-101) in Patients With Previously Treated Low-grade Lymphoma
Status: COMPLETED
Conditions: Indolent Non-Hodgkin's Lymphoma|Follicular Lymphoma|Small Lymphocytic Lymphoma|Marginal Zone Lymphoma
Interventions: DRUG: Idelalisib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pumps for Kids, Infants and Neonates (PumpKIN): The Jarvik 2015 Pivotal Trial
Status: NOT_YET_RECRUITING
Conditions: Heart Failure With Reduced Ejection Fraction|Pediatric HD, Stage IV|LVAD
Interventions: DEVICE: Jarvik 2015 LVAD
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Safety of Coadministered Pitavastatin and Valsartan in Patients With Hypertension and Dyslipidemia
Status: COMPLETED
Conditions: Hypertension|Dyslipidemia
Interventions: DRUG: pitavastatin, valsartan, placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial Comparing Circumferential Casting Versus Splinting in Displaced Colles' Fractures
Status: COMPLETED
Conditions: Colles' Fracture
Interventions: DEVICE: Cylindrical cast|DEVICE: Modified sugar tong cast|DEVICE: Volar dorsal splint
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Alpha Radiation Emitters Device for the Treatment of Pancreatic Cancer Emitters for the Treatment of Locally Advanced Pancreatic Cancer
Status: NOT_YET_RECRUITING
Conditions: Pancreatic Cancer|Unresectable Pancreatic Cancer|Pancreatic Adenocarcinoma
Interventions: DEVICE: DaRT seeds insertion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Two Titration Algorithms With Insulin Glargine 300 Units/mL in Type 2 Diabetes Mellitus Patients
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: INSULIN GLARGINE (U300)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ability of a Dendritic Cell Vaccine to Immunize Melanoma or Epithelial Cancer Patients Against Defined Mutated Neoantigens Expressed by the Autologous Cancer
Status: TERMINATED
Conditions: Melanoma|Gastrointestinal Cancer|Breast Cancer|Ovarian Cancer|Pancreatic Cancer
Interventions: BIOLOGICAL: Peptide loaded dendritic cell vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Validation of Point-of-care Thromboelastography (TEG 6s) in Pediatric Patients
Status: RECRUITING
Conditions: Coagulopathy
Interventions: DIAGNOSTIC_TEST: Thromboelastography (TEG 6S)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Evaluate the Effect of Food on Fixed-Dose Combination of MP-513 10 mg and Metformin XR 750 mg
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: FDC(MP-513 10mg/Metformin XR 750mg)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effect of a CCK-1R Agonist on Food Intake in Humans
Status: TERMINATED
Conditions: Bulimia
Interventions: DRUG: GSKI181771X (CCK-1R agonist)|BEHAVIORAL: Instructions to binge eat|BEHAVIORAL: Instructions to eat normally|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Urinary Retention After Removing Urinary Catheter at 24 Hour Versus 48 Hour in Patients With Vaginal Surgery
Status: COMPLETED
Conditions: Urinary Retention|Pelvic Organ Prolapse
Interventions: PROCEDURE: Removing urinary catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Priming During Induction and Consolidations in Younger Acute Myeloid Leukemia (AML)
Status: COMPLETED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: GM-CSF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: START-MET HS Prostate Cancer. : SbrT & Androgen Receptor Therapy METastatic HSPC
Status: RECRUITING
Conditions: Prostate Cancer|Stereotactic Body Radiation Therapy
Interventions: RADIATION: SBRT|RADIATION: STANDARD OF CARE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Effect of Lixisenatide in Patient With Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: DRUG: Lixisenatide|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: BAY 59-7939 (Xarelto, SPAF), Non Interventional Studies
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DRUG: Phenprocoumon (Marcumar)|DRUG: Rivaroxaban (Xarelto, BAY-59 7939)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Fixation Methods of Basicervical Fractures
Status: COMPLETED
Conditions: Hip Fractures|Osteoporotic Fractures
Interventions: DEVICE: cephalomedullary nail|DEVICE: sliding hip screw
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Doxorubicin, CC-(486) (5-azacitidine), Romidepsin, and Duvelisib (hARD) for T-cell Lymphoma
Status: WITHDRAWN
Conditions: Adult T-cell Leukemia/Lymphoma|Extranodal NK-/T-cell Lymphoma, Nasal Type|Enteropathy-Associated T-Cell Lymphoma|Monomorphic Epiteliotrophic Intestinal T-cell Lymphoma|Hepatosplenic T-cell Lymphoma
Interventions: DRUG: CC-486 (5-azacitidine)|DRUG: Duvelisib|DRUG: Romidepsin|DRUG: Doxorubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Kinetic Oscillation Stimulation (KOS) of Nasal Mucosa in Non-allergic Rhinitis: Investigation of Treatment Procedure
Status: COMPLETED
Conditions: Non-allergic Rhinitis.
Interventions: DEVICE: PBASE system 1.1 (active treatment)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vascular Effects of Rosiglitazone Versus Glyburide in Type 2 Diabetic Patients
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: rosiglitazone|DRUG: glyburide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety Evaluation of Alirocumab (SAR236553/REGN727) in Patients With Primary Hypercholesterolemia on Stable Atorvastatin Therapy
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DRUG: Alirocumab|DRUG: Placebo (for alirocumab)|DRUG: Atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Performance of Flowable Giomer Versus Nanofilled Composite in Conservative Occlusal Cavities
Status: NOT_YET_RECRUITING
Conditions: Occlusal Caries
Interventions: OTHER: Flowable Giomer|OTHER: Flowable Nano-filled composite with S-PRG barrier coat|OTHER: Flowable Nano-filled composite
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fingolimod in Preventing Paclitaxel-Associated Neuropathy in Patients With Breast Cancer
Status: COMPLETED
Conditions: Breast Carcinoma
Interventions: DRUG: Fingolimod|DRUG: Fingolimod Hydrochloride|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Pilot Study to Evaluate 18F-fluorodeoxyglucose (FDG) Positron Emission Tomography /Computed Tomography (PET/CT) in Prediction of Early Response to Chemotherapy in Ovarian Cancer.
Status: COMPLETED
Conditions: Ovarian Cancer
Interventions: PROCEDURE: 1: FDG PET
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of the Composition and Bacterial Diversity of the Vaginal Microbiota in Healthy Versus Pathological Conditions (Bacterial Vaginosis) Using a Targeted Metagenomic Approach (RNA 16s)
Status: COMPLETED
Conditions: Vaginosis, Bacterial
Interventions: DIAGNOSTIC_TEST: vaginal swabs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Virtual Reality for GI Cancer Pain to Improve Patient Reported Outcomes
Status: RECRUITING
Conditions: Cancer Pain|Visceral Pain|Gastrointestinal Neoplasms|Cancer of Gastrointestinal Tract|Small Intestine Cancer|Pancreas Cancer|Liver Cancer|Colon Cancer|Biliary Tract Cancer|Stomach Cancer|Rectum Cancer|Peritoneal Cancer|Gastrointestinal Cancer Metastatic|Gastrointestinal Cancers - Anus|Gastrointestinal Cancers - Stomach|Gastrointestinal Cancers - Colorectal|Gastrointestinal Cancers - Small Intestine|Small Intestine Cancer Stage III|Small Intestine Cancer Stage IV|Small Intestine Cancer, Recurrent|Pancreas Cancer, Stage III|Pancreas Cancer, Stage IV|Pancreas Cancer, Metastatic|Pancreas Cancer, Recurrent|Liver Cancer Stage IIIa|Liver Cancer Stage IIIb|Liver Cancer Stage IIIc|Liver Cancer Stage IV|Colon Cancer Stage III|Colon Cancer Stage IV|Stomach Cancer Stage III|Stomach Cancer Stage IV|Stomach Cancer Recurrent|Rectum Cancer, Recurrent|Gastrointestinal Cancers - Liver|Anal Cancer|Anal Cancer Stage III|Anal Cancer Stage IV|Anal Cancer Recurrent|Anal Cancer Metastatic|Anal Cancer, Stage IIIA|Anal Cancer, Stage IIIB|Appendix Cancer|Ampullary Cancer|Bile Duct Cancer|Bile Duct Cancer Stage III|Bile Duct Cancer Stage IV|Bile Duct Cancer Stage IVA|Bile Duct Cancer Stage IVB|Bile Duct Cancer Recurrent|Carcinoid Tumor|Carcinoid Tumor of Pancreas|Carcinoid Tumor of Large Intestine|Carcinoid Tumor of GI System|Carcinoid Tumor of Colon|Carcinoid Tumor of Liver|Carcinoid Tumor of Cecum|Carcinoid Tumor of Ileum|Carcinoid Tumor of Rectum|Carcinoid Tumor of the Small Bowel|Carcinoid Tumor of the Stomach|Large Intestine Cancer|Esophagus Cancer|Esophagus Cancer, Stage III|Esophagus Cancer, Stage IV|Esophagus Cancer, Recurrent|Gallbladder Cancer|Gallbladder Cancer Stage III|Gallbladder Cancer Stage IV|Gastric (Stomach) Cancer|Neuroendocrine Tumor|Peritoneum Cancer|Rectal Cancer|Esophagus Cancer, Stage I|Esophagus Cancer, Stage II|Gallbladder Cancer Stage I|Gallbladder Cancer Stage II|Bile Duct Cancer Stage I|Bile Duct Cancer Stage II
Interventions: DEVICE: PICO G2 4k
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pharmacokinetics of Pantoprazole and CYP2C19 Activity in Children and Adolescents With GERD: A Pilot Study
Status: COMPLETED
Conditions: Obesity|GERD
Interventions: DRUG: Pantoprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Low Glycemic Index Diet for Prevention of Glucose Intolerance During Bed Rest
Status: COMPLETED
Conditions: Glucose Intolerance
Interventions: DIETARY_SUPPLEMENT: Low glycemic index, pulse-based diet|DIETARY_SUPPLEMENT: Moderate glycemic index hospital diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Rapid Transfusion With Fluid Management System 2000® (FMS)
Status: COMPLETED
Conditions: Liver Transplantation
Interventions: DEVICE: Fluid management system 2000 (FMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Molecular and Clinical Effects of Green Tea and Fermented Papaya Preparation on Diabetes and Cardiovascular Diseases
Status: COMPLETED
Conditions: Assess the Effect of Green Tea on Diabetes|Assess the Effect of Fermented Papaya Pretration on Diabetes|Effects of Green Tea and FPP on C-reactive Proteins|Effects of Green Tea and FPP of Lipid Profiles in Diabetes|Effect of Green Tea and FPP on Atheroma Formation
Interventions: DIETARY_SUPPLEMENT: Green tea|DIETARY_SUPPLEMENT: FPP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dapagliflozin + Saxagliptin in a Basal-bolus Insulin Treatment
Status: TERMINATED
Conditions: Type 2 Diabetes
Interventions: DRUG: Dapagliflozin 10 mg + Saxagliptin 5 mg|DRUG: Placebo 1 10 mg + Placebo 2 5 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Non-Expert Acquisition & Remote Expert Review of Screening Echocardiography Images From Child Health & AnteNatal Clinics
Status: NOT_YET_RECRUITING
Conditions: Rheumatic Heart Disease
Interventions: DIAGNOSTIC_TEST: SPLASH echocardiography screening
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Impact of Albendazole -Ivermectin on Wuchereria Bancrofti in Mali
Status: COMPLETED
Conditions: Lymphatic Filariasis
Interventions: DRUG: ''albendazole'' and ''ivermectin''
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multidisciplinary Approach to Assessing and Treating Fatigue in Inflammatory Bowel Disease
Status: RECRUITING
Conditions: Inflammatory Bowel Diseases|Fatigue
Interventions: BEHAVIORAL: Exercise Intervention|BEHAVIORAL: Acceptance and Commitment Therapy|DIETARY_SUPPLEMENT: Probiotic
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics of Lopinavir/Ritonavir at Three Different Doses.
Status: COMPLETED
Conditions: Acquired Immunodeficiency Syndrome
Interventions: DRUG: lopinavir/ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bosutinib in Pediatric Patients With Newly Diagnosed Chronic Phase or Resistant/Intolerant Ph + Chronic Myeloid Leukemia
Status: ACTIVE_NOT_RECRUITING
Conditions: Philadelphia Chromosome Positive CML|Accelerated Phase Chronic Myelogenous Leukemia|Blastic Phase Chronic Myelogenous Leukemia|Chronic Phase Chronic Myelogenous Leukemia
Interventions: DRUG: Bosutinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Emergence Delirium in Children: Total Intravenous Anesthesia With Propofol and Remifentanil Versus Inhalational Sevoflurane Anesthesia
Status: COMPLETED
Conditions: Emergence Delirium
Interventions: DRUG: Propofol|DRUG: sevoflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Perform Humeral System Study
Status: RECRUITING
Conditions: Osteoarthritis Shoulder|Avascular Necrosis|Post-traumatic Arthrosis of Other Joints, Shoulder Region|Rotator Cuff Tear Arthropathy
Interventions: DEVICE: Tornier Perform Humeral - Stem
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of an ER Beta Agonist (Lilly Compound LY500307) on Estradiol-Withdrawal-Induced Mood Symptoms in Women With Past Perimenopausal Depression
Status: RECRUITING
Conditions: Perimenopause-Related Depression
Interventions: DRUG: ER beta agonist|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Open-label Trial to Evaluate the Effect Carbamazepine on Darigabat Pharmacokinetics in Healthy Adult Participants
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DRUG: Darigabat|DRUG: Carbamazepine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Kinesiotaping Augmented By Resistive Exercise on Fatigue, Physical Strength, Quality of Life in Breast Cancer Survivors
Status: NOT_YET_RECRUITING
Conditions: Breast Cancer|Fatigue|Quality of Life
Interventions: OTHER: resistive training|OTHER: kinesiotaping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Imaging of Patients With Known or Suspected Somatostatin Receptor Positive Neuroendocrine Tumors Using Cu64-DOTATATE
Status: COMPLETED
Conditions: Neuroendocrine Tumors
Interventions: DRUG: 64Cu-DOTATATE
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Phase 1B Study of Canakinumab, Spartalizumab, Nab-paclitaxel, and Gemcitabine in Metastatic PC Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Pancreatic Ductal Adenocarcinoma
Interventions: DRUG: Canakinumab injection; spartalizumab, nab-paclitaxel, gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acupuncture for the Treatment of Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DEVICE: Acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Extracorporeal Shockwave Myocardial Revascularization in Refractory Angina
Status: COMPLETED
Conditions: Angina Refractory|Angina Pectoris
Interventions: OTHER: Extracorporeal Shockwave Myocardial Revascularization
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Analgesic Effect of Volatile Anesthetics
Status: COMPLETED
Conditions: Anesthesia
Interventions: DRUG: Sevoflurane|DRUG: Desflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The DANish COronary DEcalcification (DANCODE) Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Coronary Artery Disease
Interventions: DIETARY_SUPPLEMENT: Vitamin K2 (Menaquinone-7)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Phytolacca Decandra and Melissa Officinalis in Children With Nocturnal Bruxism
Status: UNKNOWN
Conditions: Nocturnal Bruxism
Interventions: DRUG: Phytolacca decandra|DRUG: Melissa officinalis|DRUG: Phyt.decandra + Melissa offic.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Sym023 (Anti-TIM-3) in Patients With Advanced Solid Tumor Malignancies or Lymphomas
Status: COMPLETED
Conditions: Metastatic Cancer|Solid Tumor|Lymphoma
Interventions: DRUG: Sym023
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Innovative Steroid Treatment to Reduce Asthma Development in Children After First-time Rhinovirus Induced Wheezing
Status: RECRUITING
Conditions: Asthma|Inflammation
Interventions: DRUG: Dexamethasone treatment during 3 days|DRUG: placebo treatment during 3 days
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Stereotactic Body Radiation Therapy (SBRT) for Unresectable Liver Metastases
Status: RECRUITING
Conditions: Liver Metastases|Colorectal Cancer|Anal Canal Cancer|Gastrointestinal Neuroendocrine Tumors
Interventions: RADIATION: SBRT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Biomarker Study Comparing the Combination of BRAF Inhibitor Dabrafenib With MEK Inhibitor Trametinib Versus the Combination After Monotherapy With Dabrafenib or Trametinib
Status: TERMINATED
Conditions: Melanoma
Interventions: DRUG: Dabrafenib|DRUG: Trametinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Sorafenib and High-Dose Carboplatin, Paclitaxel, and External-Beam Radiation Therapy in Treating Patients With Stage III Non-Small Cell Lung Cancer
Status: WITHDRAWN
Conditions: Lung Cancer
Interventions: DRUG: carboplatin|DRUG: paclitaxel|DRUG: sorafenib tosylate|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dapagliflozin vs Empagliflozin on Flow Mediated Dilation in Type 2 Diabetes Mellitus
Status: UNKNOWN
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Dapagliflozin Pill|DRUG: Empagliflozin Pill|DRUG: Placebo pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Osteopathy and Obstructive Sleep Apnea Syndrome II
Status: COMPLETED
Conditions: Obstructive Sleep Apnea Syndrome
Interventions: PROCEDURE: Osteopathic manipulative treatment|PROCEDURE: sham comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Assess the Safety and Efficacy of Sodium Stibogluconate (SSG) and AmBisome® Combination, Miltefosine and AmBisome® and Miltefosine Alone for the Treatment Visceral Leishmaniasis in Eastern Africa
Status: COMPLETED
Conditions: Primary Visceral Leishmaniasis
Interventions: DRUG: Liposomal amphotericin B (AmBisome®) and sodium stibogluconate|DRUG: Liposomal amphotericin B + miltefosine|DRUG: Miltefosine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endoscopic Injection of Dextranomer/Hyaluronic Acid Versus Ureteral Reimplantation In Treatment of Vesicoureteral Reflux
Status: COMPLETED
Conditions: Vesico-Ureteral Reflux
Interventions: PROCEDURE: subureteral endoscopic Injection of Dextranomer/Hyaluronic acid (Dexell)|PROCEDURE: open ureteral reimplantation (Lich-Gregoir)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Small Doses of Dexmedetomidine for Emergence Agitation
Status: UNKNOWN
Conditions: Emergence Agitation
Interventions: DRUG: Sevoflurane|DRUG: Dexmedetomidine|DRUG: Placebo(for Dexmedetomidine)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Effect of Anesthetic Method on Optic Nerve Sheath Diameter in Patients Undergoing RALP
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: Dexmedetomidine|OTHER: Without dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Spinal Cord Stimulation Assisted by Motor Rehabilitation Training for Restoring Motor Function After Spinal Cord Injury
Status: RECRUITING
Conditions: Spinal Cord Injuries
Interventions: PROCEDURE: Spinal cord stimulation surgery (device) and motor rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neuromuscular Block and Anesthetic Depth Monitoring
Status: COMPLETED
Conditions: Cholecystectomy, Laparoscopic
Interventions: DRUG: Rocuronium (MB group)|DRUG: Rocuronium (DB group)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparative Volumetric Assessment of Alveolar Ridge Preservation Utilizing Different Bone Grafting Materials
Status: TERMINATED
Conditions: Tooth Fractures|Tooth Injuries|Tooth Diseases
Interventions: BIOLOGICAL: Allograft, Membrane|BIOLOGICAL: Alloplast, Membrane|BIOLOGICAL: Xenograft, Membrane|BIOLOGICAL: Membrane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT