pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Phase III Trial Investigating the Potential Benefit of Adjvant Chemotherapy for Small Bowel Adenocarcinoma
Status: UNKNOWN
Conditions: Small Bowel Adenocarcinoma|Adjuvant Chemotherapy for SBA
Interventions: DRUG: observation alone|DRUG: LV5FU2|DRUG: FOLFOX
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Study Evaluating the Effect of Moving Virtual Scenes on Postural Balance in a Stroke Rehabilitation Setting
Status: NOT_YET_RECRUITING
Conditions: Stroke Rehabilitation|Postural Equilibrium
Interventions: OTHER: Assessing postural responses induced by visual stimulation (Visual Evoked postural responses, VEPR)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Ifosfamide With or Without O(6)-Benzylguanine in Treating Patients With Unresectable, Metastatic Solid Tumors
Status: TERMINATED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: ifosfamide|DRUG: O6-benzylguanine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 3 Study of OTO-201 in Acute Otitis Externa
Status: COMPLETED
Conditions: Acute Otitis Externa|Swimmer's Ear
Interventions: DRUG: 12 mg ciprofloxacin|DRUG: Sham Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of TA-650 in Patients With Behcet's Disease (BD) With Special Lesions
Status: COMPLETED
Conditions: Behcet's Disease|Behcet Syndrome|Neuro-Behcet's Disease
Interventions: DRUG: TA-650
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Remediation of Impaired Self-Regulation in Patients With Mild TBI
Status: COMPLETED
Conditions: Mild Traumatic Brain Injury
Interventions: DRUG: Tolcapone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Safety of Alogliptin Used Combination With Thiazolidine in Participants With Type 2 Diabetes in Japan
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Alogliptin and pioglitazone|DRUG: Alogliptin and pioglitazone|DRUG: Pioglitazone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Interaction Trial Ibudilast and Methamphetamine
Status: COMPLETED
Conditions: Methamphetamine-dependence|Substance Abuse
Interventions: DRUG: Ibudilast 20mg|DRUG: Ibudilast 50mg|DRUG: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Donor-derived Anti-CD123-CART Cells for Recurred AML After Allo-HSCT
Status: UNKNOWN
Conditions: Adult Acute Myeloid Leukemia
Interventions: BIOLOGICAL: CD123CAR-41BB-CD3zeta-EGFRt-expressing T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Effectiveness Study of BCI-540 Versus Placebo in the Treatment of Major Depressive Disorder With Concomitant Anxiety
Status: COMPLETED
Conditions: Major Depressive Disorder|Anxiety
Interventions: DRUG: BCI-540
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Low Intensity Laser Therapy in Connective Tissue Graft for Root Coverage in Smokers
Status: UNKNOWN
Conditions: Gingival Recession
Interventions: PROCEDURE: CTG|DEVICE: LLLT|DEVICE: SHAM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lycra Orthosis as Therapy for the Upper Limb After Stroke
Status: COMPLETED
Conditions: Stroke|Cerebrovascular Accident
Interventions: DEVICE: Dynamic Lycra Orthosis|OTHER: Usual Rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Influence of Head and Neck Position on the Cuff Pressure Using Nasotracheal Tube
Status: UNKNOWN
Conditions: Adult Patients Over 20 Years of Age Who Require Intubation of the Nasotracheal Tube to Undergo Oral and Maxillofacial Surgery Under General Anesthesia
Interventions: PROCEDURE: Neutral position|PROCEDURE: Head extension position|PROCEDURE: Head flexion position|PROCEDURE: Head rotation position
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: DIAGNOSTIC
Clinical trial: PTCy + Sirolimus/VIC-1911 as GVHD Prophylaxis in Myeloablative PBSC Transplantation
Status: RECRUITING
Conditions: Acute Leukemia|Myelodysplastic Syndromes|Myeloproliferative Neoplasm|Lymphoma
Interventions: DRUG: VIC- 1911
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Extended-Release Melatonin in Patients With Rapid Eye Movement Sleep Behavior Disorder
Status: TERMINATED
Conditions: Rapid Eye Movement Sleep Behavior Disorder|Parkinson Disease
Interventions: DIETARY_SUPPLEMENT: Immediate Release Melatonin|DIETARY_SUPPLEMENT: Extended Release Melatonin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Cholecyst- Versus Cystic Duct Cholangiography During Laparoscopic Cholecystectomy
Status: COMPLETED
Conditions: Laparoscopic Cholecystectomy|Gall Stone Disease|Biliary Tract Anatomy|Common Bile Duct Stones.
Interventions: PROCEDURE: cholecystocholangiography|PROCEDURE: cystic duct cholangiography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Four vs. Ten Local Anesthetic Injections for SMR
Status: COMPLETED
Conditions: Submucosal Resection of the Nasal Septum (SMR)
Interventions: OTHER: suprazygomatic maxillary area infiltration|OTHER: non-suprazygomatic maxillary area placebo|OTHER: non-suprazygomatic maxillary area infiltration|OTHER: suprazygomatic maxillary area placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Meta-analyses of the Effect of Important Food Sources of Sugars on Cardiometabolic Risk Factors
Status: UNKNOWN
Conditions: Dyslipidemia|Diabetes|Prediabetes|Dysglycemia|Gout|Hypertension|Non-alcoholic Fatty Liver Disease|Cardiovascular Disease
Interventions: OTHER: Fructose-containing Sugars
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Relationship Between The Stomatognathic System, Spine Posture And Pelvic Symmetry
Status: COMPLETED
Conditions: Stomatognathic System|Spine|Pelvis|Posture
Interventions: DEVICE: Thoracic kyphosis and lumbar lordosis angle assessment|DEVICE: Temporomandibular range of motion|DEVICE: Measuring the cervical joint range of motion|DEVICE: Craniovertebral angle measurement|DEVICE: Tragus-to-wall distance measurement|DEVICE: Scoliosis angle assessment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phase II Study of Tailored-Dose Docetaxel in Metastatic Breast Cancer
Status: COMPLETED
Conditions: Metastatic Breast Cancer
Interventions: DRUG: Docetaxel|PROCEDURE: Erythromycin Breath Test (ERMBT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hyperpolarized Pyruvate (13C) MR Imaging in Monitoring Patients With Prostate Cancer on Active Surveillance
Status: RECRUITING
Conditions: Prostate Adenocarcinoma|Prostate Cancer
Interventions: DRUG: Hyperpolarized Carbon C 13 Pyruvate|PROCEDURE: Magnetic Resonance Spectroscopic Imaging|PROCEDURE: MRI Ultrasound Fusion Guided Biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: TD-1473 Absorption, Distribution, Metabolism and Excretion (ADME) Study in Healthy Male Subjects
Status: COMPLETED
Conditions: Intestinal Disorders|Bowel Diseases, Inflammatory
Interventions: DRUG: TD-1473 oral capsule|DRUG: [14C]-TD-1473 IV bolus|DRUG: [14C]-TD-1473 Oral Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Alterations of Blood Clotting With the Use of Sequential Compression Devices on the Lower Limbs
Status: TERMINATED
Conditions: Coagulation, Blood|Compression Devices, Intermittent Pneumatic|Postoperative Complications|Thrombelastography
Interventions: DEVICE: Sequential compression device therapy|DRUG: Dalteparin|PROCEDURE: TEG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Beneficial Effects of Vitamin D Combined With Oral Iron Supplementation in Patients With Chronic Heart Failure and Iron Deficiency
Status: NOT_YET_RECRUITING
Conditions: Heart Failure|Iron-deficiency|Heart Failure, Systolic|Heart Failure NYHA Class II|Heart Failure NYHA Class III|Vitamin D Deficiency
Interventions: DRUG: Sucrosomial iron|DRUG: Vitamin D|DRUG: Ferric Carboxymaltose 50 MG/ML
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Difference of Microparticles in Patients With Psoriasis Vulgaris Who Received Stelara(Ustekinumab)
Status: UNKNOWN
Conditions: Psoriasis With Cell-derived Microparticles
Interventions: DRUG: Ustekinumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Assess the Interaction Between Sunitinib and Ketoconazole to Reduce the Dose and Cost of Sunitinib
Status: COMPLETED
Conditions: Cancer
Interventions: DRUG: Sunitinib|DRUG: Sunitinib and Ketoconazol|DRUG: Sunitiinb and Ketoconazol|DRUG: Sunitinib and Ketoconazol|DRUG: Sunitinib and Ketoconazol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dual Trigger Versus GnRHa Trigger Combined With Luteal HCG Administration
Status: RECRUITING
Conditions: Infertility
Interventions: DRUG: GnRHa and HCG|DRUG: GnRHa then HCG (single low-dose)|DRUG: GnRHa then HCG (multiple low-doses)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparing Paper-based and Tablet-delivered Informed Consent for Older Adults
Status: COMPLETED
Conditions: Tablet-delivered Informed Consent|Paper-based Informed Consent
Interventions: OTHER: Randomized- paper consent|OTHER: Randomized- Tablet-delivered consent|OTHER: Focus Group- paper and tablet consent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Ischemia/Reperfusion Injury of Human Endothelium: Role of Glucose and Statins
Status: COMPLETED
Conditions: Hyperglycemia
Interventions: DRUG: 5% dextrose|DRUG: Vitamin C|DRUG: Simvastatin|DRUG: Sevoflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Lenvatinib Combined Pembrolizumab in Advanced Hepatobiliary Tumors
Status: COMPLETED
Conditions: Liver Neoplasm Malignant Primary|Cholangiocarcinoma|Combinational Immunotherapy|Biomarker
Interventions: DRUG: Lenvatinib plus Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Supplementation Performance And Exercise With Euterpe Edulis for Men's Enhancement
Status: NOT_YET_RECRUITING
Conditions: Clinical Trial
Interventions: DIETARY_SUPPLEMENT: Euterpe Edulis juice|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Short Term Effect of Vitamin D Supplementation on the Clinical Outcomes in Patients Undergoing Valve Replacement Surgery
Status: COMPLETED
Conditions: Cardiac Valve Replacement Complication
Interventions: DRUG: Alfacalcidol 1 MCG Oral Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Improving Blood Pressure Management in Patients With Diabetes
Status: COMPLETED
Conditions: Hypertension|Diabetes Mellitus, Type 1|Diabetes Mellitus, Type 2
Interventions: BEHAVIORAL: Lifestyle Counselling; Opinion Leader Influence Statements
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective Randomized Blinded Trial of VersaWrap Tendon Protector for Zone 2 Flexor Tendon Injuries
Status: RECRUITING
Conditions: Flexor Tendon
Interventions: PROCEDURE: Standard of Care Surgical Procedure|DEVICE: VersaWrap Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: The Anchor Study: Digitally Delivered Intervention for Reducing Problematic Substance Use
Status: COMPLETED
Conditions: Alcohol Use Disorder (AUD)|Substance Use Disorders
Interventions: DEVICE: W-SUDs|OTHER: Digitally-delivered Psychoeducation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Teripalimab Plus Chemotherapy in Local Advanced Esophageal Cancer
Status: UNKNOWN
Conditions: Squamous Cell Carcinoma|Esophageal Cancer|Perioperative Period
Interventions: DRUG: teripalimab plus chemotherapy|DRUG: chemotherapy plus teripalimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reducing High Risk Primary Tumor Clinical Target Volumes (CTVp1) in Non-metastatic Nasopharyngeal Carcinoma
Status: RECRUITING
Conditions: Nasopharyngeal Carcinoma|Intensity-Modulated Radiotherapy
Interventions: RADIATION: Reduction CTVp1|RADIATION: Non-reduction CTVp1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Using Behavioral Therapy in Combination With Darifenacin for Symptoms of Overactive Bladder
Status: COMPLETED
Conditions: Urinary Incontinence
Interventions: DRUG: Darifenacin|DRUG: Darifenacin|BEHAVIORAL: Behavioral therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Unicompartmental Knee Arthroplasty vs High Tibial Osteotomy.
Status: COMPLETED
Conditions: Knee Osteoarthritis|Knee Arthroplasty
Interventions: PROCEDURE: Unicompartmental Knee Replacement|PROCEDURE: High Tibial Osteotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Helping College Students With ADHD Lead Healthier Lifestyles
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder|Alcohol-Related Disorders|Substance-Related Disorders
Interventions: BEHAVIORAL: SUCCEEDS Program|BEHAVIORAL: Living a Healthy College Lifestyle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Regimen of Alfentanil in Propofol Sedative Fibro-bronchoscopy
Status: COMPLETED
Conditions: Hypoxemia
Interventions: DRUG: Alfentanil|DRUG: Normal saline|DEVICE: Targeted controlled infusion|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: ON-SCENE Initiation of Extracorporeal CardioPulmonary Resuscitation During Refractory Out-of-Hospital Cardiac Arrest
Status: RECRUITING
Conditions: Extracorporeal Membrane Oxygenation|Cardiac Arrest
Interventions: PROCEDURE: ECPR
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Phase II Trial of Dose Dense Docetaxel in N+ Breast Cancer
Status: COMPLETED
Conditions: Node Positive Breast Cancer
Interventions: PROCEDURE: 6 TEC q 3 weeks|PROCEDURE: 4 EC q 2 weeks followed by 4 TXT q 2 weeks|PROCEDURE: 4 TXT q 2 weeks followed by 4 EC q 2 weeks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Enzalutamide and M9241 in PET Positive Recurrent Prostate Cancer (pprPC) Without Testosterone Lowering Therapy
Status: RECRUITING
Conditions: Prostate Cancer|Recurrent Prostate Cancer|PET Positive
Interventions: DRUG: Enzalutamide|DRUG: M9241
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of EOSP Between Usg Guided S-FICB vs USG Guided PENG Block in Pts Undergoing Femur Fracture Surgery
Status: RECRUITING
Conditions: Post Operative Pain|Bradycardia|Hypotension|Femur Fracture
Interventions: DRUG: USG GUIDED SUPRA-INGUINAL FASCIA ILIACA BLOCK|DRUG: PERICAPSULAR NERVE BLOCK
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dapagliflozin in Reducing Epicardial Adipose Tissue in Heart Failure with Preserved Ejection Fraction
Status: NOT_YET_RECRUITING
Conditions: Heart Failure with Preserved Ejection Fraction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Speech and Voice Outcomes Following HD-tDCS Over the Left SMA
Status: NOT_YET_RECRUITING
Conditions: Parkinson Disease
Interventions: DEVICE: Active transcranial direct current stimulation|DEVICE: Sham transcranial direct current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerance of Zidovudine With Probenecid and the Effect of Probenecid on Zidovudine Pharmacokinetics Over Four Weeks
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Probenecid|DRUG: Zidovudine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Interleukin-4Ra Blockade by Dupilumab Decreases Staphylococcus Colonization and Increases Microbial Diversity in CRSwNP
Status: RECRUITING
Conditions: Nasal Polyps|Staphylococcus Aureus
Interventions: DRUG: Dupilumab Prefilled Syringe
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial to Evaluate the Efficacy and Safety of a Combination Therapy of Candesartan and Amlodipine Versus Candesartan Monotherapy in Hypertensive Patients Inadequately Controlled by Candesartan Monotherapy
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Candesartan 16mg|DRUG: Amlodipine 5mg|DRUG: Amlodipine 10mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy on Spasticity Symptoms of a Cannabis Sativa Extract in Motor Neuron Disease
Status: COMPLETED
Conditions: Motor Neuron Disease|Amyotrophic Lateral Sclerosis (ALS)
Interventions: DRUG: Cannabis Sativa extract Oromucosal spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A 14-week, Multi-center Study of [S,S]-Reboxetine in Patients With Fibromyalgia.
Status: COMPLETED
Conditions: Fibromyalgia
Interventions: DRUG: [S,S]-Reboxetine|DRUG: Placebo|DRUG: [S,S]-Reboxetine|DRUG: [S,S]-Reboxetine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of SAR156597 in the Treatment of Idiopathic Pulmonary Fibrosis
Status: COMPLETED
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: DRUG: SAR156597|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Transversus Abdominal Plane Block at Total Laparoscopic Hysterectomy: Effect on Quality of Recovery
Status: COMPLETED
Conditions: Pain, Postoperative|Anesthesia
Interventions: DRUG: TAP Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study to Assess Safety and Efficacy of Engensis in Painful Diabetic Peripheral Neuropathy
Status: ACTIVE_NOT_RECRUITING
Conditions: Diabetic Neuropathy, Painful
Interventions: BIOLOGICAL: Engensis|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Heme Arginate in Healthy Male Subjects
Status: COMPLETED
Conditions: Healthy Subjects|Heme Oxygenase|Genetic Polymorphism
Interventions: DRUG: saline solution|DRUG: heme arginate|DRUG: heme arginate|DRUG: heme arginate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Open-label Study of Adjunctive GNX Treatment in Children and Adults With TSC-related Epilepsy
Status: ENROLLING_BY_INVITATION
Conditions: Tuberous Sclerosis Complex
Interventions: DRUG: Ganaxolone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HED-Start: Evaluating a Positive Skills Intervention for Patients New on Haemodialysis
Status: RECRUITING
Conditions: End Stage Renal Disease on Dialysis|End Stage Renal Failure on Dialysis|End Stage Renal Disease|End Stage Kidney Disease
Interventions: BEHAVIORAL: HED-Start
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: To Evaluate the Efficacy and Safety of HUC3-053 in Patients With Dry Eye Syndrome
Status: NOT_YET_RECRUITING
Conditions: Dry Eye Syndromes
Interventions: DRUG: HUC3-053|DRUG: Hyalein Mini Drops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Sukshma Vyayama Yoga on Aromatase Inhibitor-Induced Arthralgia in Breast Cancer Survivors
Status: COMPLETED
Conditions: Breast Cancer
Interventions: BEHAVIORAL: Joint Loosening Yoga
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Probiotic for Pain Osteoarthritis
Status: UNKNOWN
Conditions: Osteoarthritis of Multiple Joints
Interventions: DIETARY_SUPPLEMENT: Experimental group|DIETARY_SUPPLEMENT: Control group|OTHER: Usual medical care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Stenting and Angioplasty With Protection in Patients at High Risk for Endarterectomy (SAPPHIRE)
Status: COMPLETED
Conditions: Carotid Artery Disease
Interventions: DEVICE: Cordis Nitinol Stent|DEVICE: PRECISE tapered stent|DEVICE: ANGIOGUARD XP Emboli Capture Guidewire (ECGW)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Novel Organic Kale Products for Prevention of Obesity/Type 2 Diabetes
Status: COMPLETED
Conditions: Type2 Diabetes
Interventions: DIETARY_SUPPLEMENT: Intervention|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Flat and Circadian Insulin Infusion Rates in Continuous Subcutaneous Insulin Infusion
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: DRUG: Insulin (circadian)|DRUG: Insulin (flat rate)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Selective Caries Removal (SCR) Versus Pulpotomy in Preventing Pulp Necrosis and Apical Periodontitis
Status: ACTIVE_NOT_RECRUITING
Conditions: Dental Caries
Interventions: OTHER: Selective Caries Removal|OTHER: Pulpotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Varithena Versus Endothermal Ablation of the Great Saphenous Vein (VERITAS)
Status: TERMINATED
Conditions: Varicose Veins
Interventions: DRUG: Varithena®|DEVICE: FDA-approved Endothermal Ablation (ETA) systems
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study to Compare T-Guard vs Ruxolitinib for Treatment of Steroid-Refractory Acute Graft-vs-Host Disease (BMT CTN 2002)
Status: TERMINATED
Conditions: Steroid-Refractory Acute Graft Versus Host Disease
Interventions: DRUG: T-Guard|DRUG: Ruxolitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Design and Implementation of a Physical Exercise Program With Virtual Reality to Improve Functional Capacities in Older People.
Status: COMPLETED
Conditions: Aging|Fall|Quality of Life
Interventions: DEVICE: Immersive Virtual Reality exercise program|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of the Accuracy and Precision of the INRatio® Prothrombin Time (PT) Monitoring System With New INRatio Test Strip Designed for Low Sample Volume and Heparin Insensitivity
Status: COMPLETED
Conditions: Pulmonary Embolism|Atrial Fibrillation|Deep Vein Thrombosis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Reactivity of the Vestibular System to Caloric Vestibular Stimulation in Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia|Healthy
Interventions: PROCEDURE: Left body temperature VS|PROCEDURE: Right body temperature VS|PROCEDURE: Left warm CVS|PROCEDURE: Right warm CVS|PROCEDURE: Left cold CVS|PROCEDURE: Right cold CVS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Tipifarnib in Treating Patients With Acute Myeloid Leukemia in Remission
Status: COMPLETED
Conditions: Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome|Adult Acute Megakaryoblastic Leukemia|Adult Acute Monocytic Leukemia|Adult Acute Myeloid Leukemia in Remission|Adult Acute Myeloid Leukemia With Inv(16)(p13.1q22); CBFB-MYH11|Adult Acute Myeloid Leukemia With Maturation|Adult Acute Myeloid Leukemia With Minimal Differentiation|Adult Acute Myeloid Leukemia With t(16;16)(p13.1;q22); CBFB-MYH11|Adult Acute Myeloid Leukemia With t(8;21); (q22; q22.1); RUNX1-RUNX1T1|Adult Acute Myeloid Leukemia With t(9;11)(p22.3;q23.3); MLLT3-KMT2A|Adult Acute Myeloid Leukemia Without Maturation|Adult Acute Myelomonocytic Leukemia|Adult Erythroleukemia|Adult Pure Erythroid Leukemia|Alkylating Agent-Related Acute Myeloid Leukemia|Myelodysplastic Syndrome With Excess Blasts|Recurrent Adult Acute Myeloid Leukemia
Interventions: PROCEDURE: Clinical Observation|DRUG: Tipifarnib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Compression Dressing After Upper Eyelid Blepharoplasty on Edema, Ecchymosis, Pain and Ocular Surface Irritation
Status: COMPLETED
Conditions: Dermatochalasis of Eyelid
Interventions: DEVICE: Compression dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Drug Eluting Balloon Angioplasty Versus Nitinol Stent Implantation in the Superficial Femoral Artery
Status: COMPLETED
Conditions: Peripheral Arterial Disease|Arterial Occlusive Diseases|Atherosclerosis|Arteriosclerosis|Cardiovascular Diseases|Peripheral Vascular Diseases|Paclitaxel|Plaque, Atherosclerotic|Critical Limb Ischemia
Interventions: DEVICE: Drug Eluting Balloon Angioplasty|DEVICE: Nitinol stenting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assess the Effectiveness of Pulse RadioFrequency in Patients With Chronic Lumbar Radicular Pain
Status: COMPLETED
Conditions: Chronic Pain|Back Pain
Interventions: OTHER: Pulsed Radiofrequency|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Oral Deforolimus With Trastuzumab for Patients With HER2-positive Trastuzumab-Refractory Metastatic Breast Cancer (8669-009)
Status: COMPLETED
Conditions: Breast Cancer|Breast Neoplasms
Interventions: DRUG: ridaforolimus|DRUG: trastuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial Using Impella LP 2.5 System in Patients With Acute Myocardial Infarction Induced Hemodynamic Instability
Status: TERMINATED
Conditions: Acute Myocardial Infarction
Interventions: DEVICE: Impella LP 2.5|DEVICE: Intra-Aortic Balloon Pump
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Mofest® 400mg (Moxifloxacin) Tablet With Avelox® 400mg (Moxifloxacin) Tablet in Healthy Pakistani Subjects
Status: COMPLETED
Conditions: Healthy Individuals|Bioequivalence Study
Interventions: DRUG: Moxifloxacin 400mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Safety of Tranexamic Acid in Reducing Bleeding in Adults Undergoing Spinal Surgery
Status: COMPLETED
Conditions: Spine Surgery
Interventions: DRUG: Tranexamic acid|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An Observational Study of Men With Premature Ejaculation Who Are Treated With Dapoxetine Hydrochloride or Alternate Care Defined as Any Treatment Other Than Dapoxetine Hydrochloride
Status: COMPLETED
Conditions: Sexual Dysfunction, Physiological|Ejaculation
Interventions: DRUG: Dapoxetine hydrochloride|OTHER: Alternate care/non-dapoxetine hydrochloride treatment(s)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of Atezolizumab Administered Alone or in Combination With Azacitidine in Participants With Myelodysplastic Syndromes
Status: COMPLETED
Conditions: Myelodysplastic Syndromes
Interventions: DRUG: Atezolizumab|DRUG: Azacitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Ayres Sensory Integration Therapy Versus Conservative Treatment in Autism Spectrum
Status: ACTIVE_NOT_RECRUITING
Conditions: Autism Spectrum Disorder
Interventions: DIAGNOSTIC_TEST: Ayres sensory integration therapy|DIAGNOSTIC_TEST: Behaviour Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Whiplash-induced Thoracic Outlet Syndrome Treated With Botulinum Toxin.
Status: UNKNOWN
Conditions: Thoracic Outlet Syndrome|Whiplash Injuries
Interventions: DRUG: IncobotulinumtoxinA 100 UNT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment Study of Soft Palatal Implants in Obstructive Sleep Apnea
Status: COMPLETED
Conditions: Sleep Apnea, Obstructive
Interventions: DEVICE: soft palate implant|OTHER: Positive airway pressure (PAP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Virtual Group Social ABCs - Multi-site Randomized Controlled Trial
Status: RECRUITING
Conditions: Autism Spectrum Disorder|Social Communication Disorder|Autism or Autistic Traits|Autism Spectrum Disorder With Impaired Functional Language|Autism-Related Speech Delay
Interventions: BEHAVIORAL: VG Social ABCs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ZIMURA in Combination With Eylea in Patients With Idiopathic Polypoidal Choroidal Vasculopathy (IPCV)
Status: WITHDRAWN
Conditions: Idiopathic Polypoidal Choroidal Vasculopathy
Interventions: DRUG: Zimura|DRUG: Eylea
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Inhalational Sedation and Mechanical Power
Status: RECRUITING
Conditions: Mechanical Ventilation|Sedation|Mechanical Power|Lung Injury|ICU
Interventions: DRUG: Inhalational sedation|DRUG: Convention sedation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Comparing Postoperative Pain Following COX-2 and Prostanoids Expression
Status: UNKNOWN
Conditions: Female Genital Disease
Interventions: DRUG: COX-2 inhibitor|DRUG: Placebo Oral Tablet|PROCEDURE: Preoperative peritoneal biopsy|PROCEDURE: Single-port laparoscopic surgery|PROCEDURE: Postoperative peritoneal biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Effect of Combination With Telmisartan and Hydrochlorothiazide in Hypertensives Uncontrolled on Amlodipine
Status: COMPLETED
Conditions: Essential Hypertension
Interventions: DRUG: telmisartan plus hydrochlorothiazide|DEVICE: Amlodipine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Effects of FX006 on Blood Glucose in Patients With OA of the Knee and Type 2 Diabetes
Status: COMPLETED
Conditions: Osteoarthritis of the Knee|Type 2 Diabetes Mellitus
Interventions: DRUG: FX006 32 mg|DRUG: TCA IR 40 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ARTEMIS-101: A Study of HS-20093 Combinations in Patients With Advanced Solid Tumors
Status: RECRUITING
Conditions: Advanced Solid Tumor
Interventions: DRUG: HS-20093|DRUG: Adebrelimab|DRUG: Cisplatin/ Carboplatin|DRUG: Cetuximab|DRUG: Enzalutamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: FemPulse Therapy for Overactive Bladder in Women
Status: UNKNOWN
Conditions: Urinary Bladder, Overactive
Interventions: DEVICE: FemPulse System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pathways of Eicosanoid Metabolism
Status: ENROLLING_BY_INVITATION
Conditions: Metabolism of Prostaglandin D2
Interventions: DIETARY_SUPPLEMENT: niacin|DRUG: aspirin|OTHER: PGD2
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect of Synaquell™ in Contact Sport Athletes
Status: RECRUITING
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Synaquell(TM)|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Phase I/II Study of ITU512 in Healthy Participants and Patients With Sickle Cell Disease
Status: RECRUITING
Conditions: Sickle Cell Disease
Interventions: DRUG: ITU512|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Impact of Picture Narrative Format on Print Lung Screening Communication Outcomes
Status: COMPLETED
Conditions: Cancer Screening
Interventions: BEHAVIORAL: Picture narrative information format|BEHAVIORAL: Text with pictures information format|BEHAVIORAL: Text-only information format
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Outcome of NSRCT Versus VPT in Management of Teeth With Symptomatic Irreversible Pulpitis Associated With Apical Periodontitis
Status: NOT_YET_RECRUITING
Conditions: Endodontically Treated Teeth
Interventions: PROCEDURE: root canal tretment|PROCEDURE: biodentin VPT|PROCEDURE: PRF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sulodexide Efficacy in Chronic Idiopathic Subjective Tinnitus
Status: COMPLETED
Conditions: Tinnitus, Subjective
Interventions: DRUG: Sulodexide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Camrelizumab and Fluzoparib and Nab-paclitaxel in Early Breast Cancer With HRR Gene Mutation
Status: RECRUITING
Conditions: Her-2 Negative Breast Cancer|HRR Gene Mutation
Interventions: DRUG: Camrelizumab|DRUG: Fluzoparib|DRUG: Nab-paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preoperative Radiotherapy and E7046 in Rectum Cancer
Status: COMPLETED
Conditions: Neoadjuvant Therapy in Rectal Cancer
Interventions: DRUG: E7046|RADIATION: Long Course Chemoradiotherapy (LCRT)|RADIATION: Short Course Radiotherapy (SCRT)|DRUG: capecitabine|DRUG: folinic acid/5-FU/oxaliplatin (mFOLFOX-6)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trends in Prevalence of 11 Site-specific Musculoskeletal Pain Among U.S. Adults, 1999-2018
Status: ENROLLING_BY_INVITATION
Conditions: Musculoskeletal Pain|Neck Pain|Low Back Pain|Joint Pain|Shoulder Pain
Interventions: OTHER: No intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Orphan Indications for CD19 Redirected Autologous T Cells
Status: RECRUITING
Conditions: Pediatric and Young Adult Patientswith Hypodiploid or t(17;19) B-ALL|Infants With Very High Risk KMT2A B-ALL|Patients With Central Nervous System Relapse Who Did Not Receive Cranial Radiation or Bone Marrow Transplantation
Interventions: BIOLOGICAL: Murine CART19
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Mobile-health Self Management on Quality of Life of Patients Undergoing Chemotherapy
Status: NOT_YET_RECRUITING
Conditions: Cancer|Chemotherapy Effect|Quality of Life|Self Efficacy
Interventions: BEHAVIORAL: Mobile-health self management
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Assessing PK and Safety of MGTA-145 in Subjects With Normal Estimated GFR and Varying Degrees of Renal Impairment
Status: COMPLETED
Conditions: Healthy|Renal Insufficiency
Interventions: BIOLOGICAL: MGTA-145
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimising the Duration of Cooling in Mild Encephalopathy
Status: ACTIVE_NOT_RECRUITING
Conditions: Neonatal Encephalopathy|Hypothermia Neonatal|Magnetic Resonance Spectroscopy
Interventions: OTHER: Therapeutic hypothermia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: dTMS in Obsessive Compulsive Disorder
Status: COMPLETED
Conditions: Obsessive-Compulsive Disorder
Interventions: DEVICE: deep TMS|DEVICE: Sham TMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Renal Artery Fibromuscular Dysplasia: From Diagnosis to Treatment
Status: COMPLETED
Conditions: Renal Artery Fibromuscular Dysplasia
Interventions: DEVICE: Intravascular Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Nimotuzumab and Radiotherapy in Pediatric Patients With Glioma
Status: COMPLETED
Conditions: Diffuse Intrinsic Brainstem Gliomas
Interventions: RADIATION: Radiotherapy|BIOLOGICAL: Nimotuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Total Hip Arthroplasty Instability and Lumbo-pelvic Kinematics: EOS Imaging Assessment of Variation in Spinal and Pelvic Parameters From Standing to Sitting
Status: COMPLETED
Conditions: Hip Fractures
Interventions: OTHER: EOS imagery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Angiotensin-II Blockade in Mitral Regurgitation
Status: COMPLETED
Conditions: Mitral Regurgitation
Interventions: DRUG: Candesartan|DRUG: atacand|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Preoperative CT-imaging With Patient-specific Computer Simulation in Transcatheter Aortic Valve Replacement
Status: RECRUITING
Conditions: Aortic Valve Stenosis
Interventions: OTHER: FEops HEARTGuide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I/II Trial of a Tetravalent Live Attenuated Dengue Vaccine in Flavivirus Antibody Naïve Children
Status: COMPLETED
Conditions: Dengue Fever
Interventions: BIOLOGICAL: Dengue Vaccine Formulation 17|BIOLOGICAL: Licensed Japanese Encephalitis (JE) Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Can Supplementation With Lactobacillus Reuteri and Omega-3 Fatty Acids During Pregnancy and Lactation Reduce the Risk of Allergic Disease in Infancy?
Status: UNKNOWN
Conditions: Allergy|Gastrointestinal Function
Interventions: DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: Omega-3 fatty acids|DIETARY_SUPPLEMENT: Refined coconut and peanut oil without L. reuteri|DIETARY_SUPPLEMENT: L. reuteri
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of the Efficacy of TOPIALYSE Baume Protect+ on Atopic Dermatis
Status: NOT_YET_RECRUITING
Conditions: Atopic Dermatitis
Interventions: OTHER: Cosmetic Product TOPIALYSE Baume Protect+
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Recruitment on Extravascular Lung Water in Acute Respiratory Distress Syndrome (ARDS)
Status: COMPLETED
Conditions: Acute Respiratory Distress Syndrome|Acute Lung Injury
Interventions: BEHAVIORAL: Recruitment maneuver|OTHER: without recruit maneuver
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Aminolaevulinic Acid Photodynamic Therapy of Cervical Persistent HPV Infection and Cervical Neoplasia
Status: COMPLETED
Conditions: Cervical Persistent High Risk HPV Infection|Cervical Intraepithelial Neoplasia
Interventions: DRUG: Aminolaevulinic acid photodynamic therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Punch vs. Drill Tunnel Use for Anchor Tunnel Creation and Correlation With Post-operative Pain
Status: ACTIVE_NOT_RECRUITING
Conditions: Rotator Cuff Tears
Interventions: PROCEDURE: suture anchor socket creation with punch|PROCEDURE: suture anchor socket creation with drill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Resiliency Training for Patients With Neurofibromatosis Via Videoconferencing With Skype
Status: COMPLETED
Conditions: Neurofibromatosis|Neurofibromatosis I|Neurofibromatosis 2|Schwannomatosis
Interventions: BEHAVIORAL: The Relaxation Response Resiliency Program (3RP) via Skype
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE