pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: An Open-Label Study of Diazoxide Choline in Patients With Genetic Obesities
Status: UNKNOWN
Conditions: SH2B1 Deficiency Obesity|Obesity Associated With PCSK1 Mutation (rs6232 Variant)|SIM1 Deficiency Obesity
Interventions: DRUG: DCCR (diazoxide choline) extended-release tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of SAR444245 Combined With Other Anticancer Therapies for the Treatment of Participants With HNSCC (Master Protocol) (Pegathor Head and Neck 204)
Status: ACTIVE_NOT_RECRUITING
Conditions: Squamous Cell Carcinoma of Head and Neck
Interventions: DRUG: Pembrolizumab|DRUG: SAR444245 (Thor-707)|DRUG: Cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Risk of Cognitive Impairment After Surgical and Transcatheter Aortic Valve Replacement
Status: COMPLETED
Conditions: Cardiovascular Disease|Aortic Valve Stenosis|Cognitive Assessments|Valve Surgery|Transcatheter Valve Replacement|Surgical Valve Replacement
Interventions: OTHER: Observational/Cognitive Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Randomized, Single Blind, Placebo Controlled, to Evaluate Efficacy and Safety of Polidocanol Injectable Foam for Treatment of Symptomatic, Visible Varicose Veins With SFJ Incompetence
Status: COMPLETED
Conditions: Varicose Veins
Interventions: DRUG: Varisolve (Polidocanol Endovenous Microfoam)|DRUG: Agitated Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Deep Brain Reorienting in Post-traumatic Stress Disorder
Status: RECRUITING
Conditions: PTSD|Post-traumatic Stress Disorder
Interventions: BEHAVIORAL: Deep Brain Reorienting (DBR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, and Immune Response of ACAM3000 Modified Vaccinia Ankara (MVA) Smallpox Vaccine in Adults
Status: COMPLETED
Conditions: Smallpox
Interventions: BIOLOGICAL: ACAM3000 MVA Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Milnacipran on Pain Processing and Functional Magnetic Resonance Imaging (fMRI) Activation Patterns in Patients With Fibromyalgia
Status: TERMINATED
Conditions: Fibromyalgia
Interventions: DRUG: Milnacipran|DRUG: Placebo|DRUG: Placebo|DRUG: Milnacipran
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Anaesthesiology Management on Paediatric Emergence Delirium Incidence
Status: NOT_YET_RECRUITING
Conditions: Emergence Delirium
Interventions: PROCEDURE: Intravenous induction and desflurane anaesthesia maintenance|PROCEDURE: Inhalation induction with sevoflurane and anaesthesia maintenance with sevoflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Lenalidomide & Adriamycin & Dexamethasone (RAD) in Newly Diagnosed, Multiple Myeloma Patients
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Lenalidomide|DRUG: Adriamycin|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Postextubation Management in Patients at Risk for Extubation Failure
Status: TERMINATED
Conditions: Ventilatory Failure
Interventions: DEVICE: BiPAP|DEVICE: HFNC
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Maintenance Treatment vs. Stepwise Drug Discontinuation in First-Episode Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia|Psychoses
Interventions: OTHER: maintained antipsychotic treatment vs. stepwise drug discontinuation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Eltrombopag Combined With Azacitidine to Treat Myelodysplastic Syndrome (MDS)
Status: COMPLETED
Conditions: Myelodysplastic Syndrome|Thrombocytopenia
Interventions: DRUG: Eltrombopag
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of PHR 160 Spray on the Outcomes of Patients With COVID-19
Status: UNKNOWN
Conditions: COVID-19
Interventions: DRUG: PHR160 Spray|DRUG: Placebo|DRUG: Standard treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cohort Study in Uganda Comparing Artesunate + Amiodaquine (Coarsucam) Versus Artemether + Lumenfantrine (Coartem) in the Treatment of Repeated Uncomplicated Plasmodium Falciparum Malaria Attacks
Status: COMPLETED
Conditions: Malaria
Interventions: DRUG: Coarsucam|DRUG: Coartem
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Validation of a Quality of Life Assessment Tool in Adult Generalized Dystonodyskinetic Syndromes Treated by Continuous Electrical Neuromodulation
Status: RECRUITING
Conditions: Dystono-dyskinetic Syndromes
Interventions: OTHER: Questionnaire (DBS-QoLs)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Orelabrutinib Combined With Pemetrexed For Relapsed/Refractory Central Nervous System Lymphoma
Status: RECRUITING
Conditions: Central Nervous System Lymphoma
Interventions: DRUG: ICP-022|DRUG: Pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Home Study of an Advanced Upper Limb Prosthesis
Status: COMPLETED
Conditions: Traumatic Amputation of Arm
Interventions: DEVICE: Advanced upper limb prosthetic device IMU controlled|DEVICE: Advanced upper limb prosthetic EMG-PR controlled
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cardioneuroablation Versus Pacemaker Implantation for the Treatment of Symptomatic Sinus Node Dysfunction
Status: UNKNOWN
Conditions: Sinus Node Dysfunction|Sick Sinus Syndrome
Interventions: PROCEDURE: Cardioneuroablation|DEVICE: Permanent dual chamber pacemaker implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of LimpiAD Cream 2.5% Plus Versus Its Vehicle and and a Basic Emollient in Patients With Atopic Dermatitis
Status: RECRUITING
Conditions: Atopic Dermatitis
Interventions: DEVICE: LimpiAD 2,5% plus cream|OTHER: Vehicle|OTHER: Emollient
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Pharmacokinetic Study of Erlotinib in Cancer Patients With Advanced Solid Tumors, With Adequate and Moderately Impaired Hepatic Function
Status: COMPLETED
Conditions: Advanced Solid Tumors
Interventions: DRUG: Tarceva, erlotinib, OSI-774
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Analgesic Effect of Oral 25% Glucose Versus Oral 24% Sucrose for Pain Relief During Heel Lance in Preterm Neonates
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Sucrose|DRUG: Glucose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: DIRECT-SAFE: A Randomized Controlled Trial of DIRECT Endovascular Clot Retrieval Versus Standard Bridging Thrombolysis With Endovascular Clot Retrieval
Status: COMPLETED
Conditions: Ischemic Stroke
Interventions: OTHER: Direct endovascular clot retrieval|OTHER: Bridging thrombolysis followed by ECR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sorafenib and Erlotinib in Treating Patients With Metastatic or Unresectable Solid Tumors
Status: COMPLETED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: erlotinib hydrochloride|DRUG: sorafenib tosylate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Benefit of Early Protocol Biopsy and Treatment of Subclinical Rejection
Status: COMPLETED
Conditions: Kidney Transplantation
Interventions: DRUG: Tacrolimus|DRUG: MMF|DRUG: Corticosteroids (Prednisone)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Study of Sequential Eribulin Followed by FAC Compared to Sequential Paclitaxel Followed by FEC in Early Stage Breast Cancer Not Overexpressing HER-2
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Paclitaxel|DRUG: Eribulin|DRUG: 5-Fluorouracil|DRUG: Epirubicin|DRUG: Cyclophosphamide|DRUG: Doxorubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study on Olaparib Plus Abiraterone as First-line Therapy in Men With Metastatic Castration-resistant Prostate Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Castration-resistant Prostate Cancer
Interventions: DRUG: olaparib|DRUG: abiraterone acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Measuring and Mapping Cognitive Decline After Brain Radiosurgery
Status: NOT_YET_RECRUITING
Conditions: Brain Metastases|Meningiomas|Stereotactic Radiosurgery|Cognitive Decline|Quality of Life|SRS
Interventions: BEHAVIORAL: Neurocognitive testing|BEHAVIORAL: Quality of Life questionnaire|RADIATION: Stereotactic radiosurgery
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Health Economic Trial in Adult Patients Undergoing Open Colectomy MA402S23B301
Status: TERMINATED
Conditions: Bowel Obstruction
Interventions: DRUG: morphine sulfate|DRUG: bupivacaine liposome extended-release injectable suspension
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Insulin Loaded Orally Dissolved Films (Insulin-ODF)
Status: UNKNOWN
Conditions: Healthy Volunteers
Interventions: DRUG: NPH-Insulin Injection|DRUG: Insulin loaded Orally Dissolved Films (insulin-ODF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Reliability and Acceptability of Real-time Virtual Video Pediatric Gait, Arms, Legs and Spine (V-pGALS)
Status: COMPLETED
Conditions: Musculoskeletal Abnormality|Pediatric
Interventions: DIAGNOSTIC_TEST: video Pediatric Gait, Arms, Legs and Spine (V-pGALS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of D07001-Softgel Capsules in Subjects With Gastrointestinal Cancer in Dose-Escalation Phase and in Subjects With Biliary Tract Cancer in Dose-Expansion Phase
Status: COMPLETED
Conditions: Gastrointestinal Cancer|Biliary Tract Cancer
Interventions: DRUG: D07001-softgel capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Intravenous VMX-C001 in Healthy Subjects and in Combination With Selected Direct Oral Anticoagulants in Healthy Older Subjects
Status: COMPLETED
Conditions: Coagulation Disorder
Interventions: DRUG: VMX-C001|DRUG: Placebo|DRUG: Apixaban|DRUG: Rivaroxaban|DRUG: Edoxaban
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Using Ultrasonography, Shear Wave Elastography, Strain Imaging, and 3-D Volume Ultrasonography on Cardiovascular Disease
Status: WITHDRAWN
Conditions: Fibromuscular Dysplasia of Arteries|Segmental Arterial Mediolysis|Spontaneous Coronary Artery Dissection|Atherosclerosis of Artery
Interventions: DEVICE: Shear Wave Elastography|DEVICE: Pulse Wave Imaging|DRUG: Contrast-Enhanced Ultrasound|OTHER: Strain Imaging|DEVICE: 3-D Volume Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Clinical Trial to Evaluate the Efficacy and Safety of UNI-DEB for Unresectable Hepatocellular Carcinoma
Status: COMPLETED
Conditions: Hepatocellular Carcinoma Non-resectable
Interventions: DEVICE: UNI-DEB
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antimicrobial Activity of IV Clear™ Dressing - Prevention of Antimicrobial Regrowth
Status: COMPLETED
Conditions: Skin Flora Infection
Interventions: DEVICE: IV Clear™ Dressing|DEVICE: Tegaderm CHG™|DEVICE: Silicone Vehicle Control Dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Hemoglobin Kinetics in Response to Mircera® in Patients With Acute Myocardial Infarction
Status: COMPLETED
Conditions: Acute Myocardial Infarction
Interventions: DRUG: methoxy-polyethyleneglycol epoetin beta
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The ENERGY 3 Study: Evaluation of Efficacy and Safety of INZ-701 in Children With ENPP1 Deficiency
Status: RECRUITING
Conditions: Ectonucleotide Pyrophosphatase/Phosphodiesterase1 Deficiency|Autosomal Recessive Hypophosphatemic Rickets|Generalized Arterial Calcification of Infancy
Interventions: DRUG: INZ-701|DRUG: Control Arm (Conventional Therapy)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose-response Relationship of Mustard Flour Footbaths in Healthy Volunteers
Status: COMPLETED
Conditions: Thermogenesis by Different-dosage Mustard Flour Footbaths
Interventions: OTHER: 3-g mustard footbath|OTHER: 6-g mustard footbath|OTHER: 12-g mustard footbath|OTHER: Warm water only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: EXPLORATORY ASSESSMENT OF THE EFFECTS OF CYCLO 3 ® FORT (Ruscus Extract, Hesperidin Methyl Chalcone, Ascorbic Acid) OR MICRONISED PURIFIED FLAVONOID FRACTION ON VASCULAR PARAMETERS AND BIOMARKERS IN WOMEN SUFFERING FROM CHRONIC VENOUS DISEASE (CEAP C2 OR C3), OVER 8 WEEKS
Status: WITHDRAWN
Conditions: Venous Disease Classification (CEAP): C2 or C3
Interventions: DRUG: CYCLO 3 ® FORT|DRUG: MPFF|DRUG: placebo CYCLO 3 ® FORT|DRUG: placebo MPFF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Efficacy, Safety, and Tolerability of Long-acting Intramuscular Cabotegravir and Rilpivirine for Maintenance of Virologic Suppression Following Switch From an Integrase Inhibitor in HIV-1 Infected Therapy Naive Participants
Status: ACTIVE_NOT_RECRUITING
Conditions: HIV Infections
Interventions: DRUG: Cabotegravir (CAB) tablet|DRUG: Rilpivirine (RPV) tablet|DRUG: Cabotegravir - Injectable Suspension (CAB LA)|DRUG: Rilpivirine - Injectable Suspension (RPV LA)|DRUG: ABC/DTG/3TC STR - Tablet|DRUG: DTG Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CLoWI Versus PCA Morphine for Pain Control After Major Abdominal Surgery
Status: COMPLETED
Conditions: Surgical Wound|Post-Op Complication|Opioid Use
Interventions: DEVICE: CLoWI|DEVICE: PCA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Docetaxel and Oxaliplatin in Gastric Cancer
Status: COMPLETED
Conditions: Stomach Neoplasms
Interventions: DRUG: Docetaxel + Oxaliplatin|DRUG: Docetaxel + Oxaliplatin + 5-FU|DRUG: Docetaxel + Oxaliplatin + Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Effects of Chronic Treatment With Olanzapine and Risperidone on Glucose and Lipid Metabolism
Status: COMPLETED
Conditions: Schizophrenia|Diabetes|Metabolic Syndrome|Hyperglycemia
Interventions: DRUG: Olanzapine|DRUG: olanzapine|DRUG: risperidone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Adjuvants Added to Bupivacaine in Adductor Canal Block
Status: COMPLETED
Conditions: Anesthesia
Interventions: DRUG: Dexamethasone|DRUG: Dexmedetomidine|DRUG: Magnesium sulfate|DRUG: Bupivacain
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: NAD-supplementation in Drug naïve Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson Disease|Neurodegenerative Diseases
Interventions: DIETARY_SUPPLEMENT: Nicotinamide Riboside|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Role of DEB-TACE Versus c-TACE in Treatment of HCC
Status: ACTIVE_NOT_RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Doxorubicin-Eluting Beads
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Function Definition and Clinical Validation of Digital Health App: Using Weight Management as An Example
Status: NOT_YET_RECRUITING
Conditions: Weight Loss|Body Fat Rate Loss|Body Composition Change
Interventions: DEVICE: "AI Mindful Eating" App|BEHAVIORAL: Outpatient regular follow-up
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Success of Lumbar Sympathetic Ganglion Block Using Lower Extremity Perfusion Index
Status: COMPLETED
Conditions: Chronic Pain|Complex Regional Pain Syndromes|Peripheral Neuropathy|Post Herpetic Neuralgia
Interventions: PROCEDURE: Lumbar Sympathetic Ganglion Block
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Electrical Brain Stimulation and Pharmacological Treatments in Autism Spectrum Disorder
Status: COMPLETED
Conditions: Autism Spectrum Disorder
Interventions: DRUG: RisperiDONE 1 MG/ML|DEVICE: transcranial direct current stimulation|DRUG: Placebo|DEVICE: sham transcranial direct current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of MEM 1003 Versus Placebo for the Treatment of Patients With Bipolar I Disorder
Status: COMPLETED
Conditions: Bipolar Disorder With Manic or Mixed Episodes
Interventions: DRUG: MEM 1003
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Topical Anesthetics: Benzocaine Versus Pliaglis
Status: COMPLETED
Conditions: Anesthesia of Mucous Membrane
Interventions: DRUG: Pliaglis|DRUG: Benzocaine|DRUG: Articaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Cannabinoid Modulation of Pain
Status: COMPLETED
Conditions: Pain
Interventions: OTHER: Thermal|OTHER: Electrical|OTHER: Capsaicin|DRUG: THC|DRUG: THC|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Clinical Evaluation of a Daily Wear Monthly Replacement Silicone Hydrogel Lens
Status: COMPLETED
Conditions: Refractive Errors
Interventions: DEVICE: Lehfilcon A contact lenses|DEVICE: Comfilcon A contact lenses|DEVICE: CLEAR CARE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Spinal Cord Stimulation for the Treatment of Pain in Chronic Pancreatitis
Status: COMPLETED
Conditions: Chronic Pancreatitis|Chronic Pain
Interventions: DEVICE: Spinal Cord Stimulation|DEVICE: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hospitalization at Home: The Acute Care Home Hospital Program for Adults
Status: COMPLETED
Conditions: Pneumonia|Heart Failure|Cellulitis|Urinary Tract Infections
Interventions: OTHER: Home hospitalization|OTHER: Inpatient Hospitalization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lymph Node Aspiration to Decipher the Immune Response of Beta-variant Recombinant Protein Booster Vaccine (VidPrevtyn Beta, Sanofi) Compared to a Bivalent mRNA Vaccine (Comirnaty Original/Omicron BA.4-5, BioNTech-Pfizer) in Adults Previously Vaccinated With at Least 3 Doses of COVID-19 mRNA Vaccine.
Status: RECRUITING
Conditions: COVID-19
Interventions: PROCEDURE: Lymph node aspiration / Blood sampling
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Complications of Mesh Procedures for Stress Urinary Incontinence
Status: COMPLETED
Conditions: Urinary Incontinence|Stress
Interventions: PROCEDURE: Tension-free vaginal tape (TVT)|PROCEDURE: Trans-obturator tape (TOT)|PROCEDURE: Suprapubic sling (SS)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Task Practice and Spinal Cord Stimulation
Status: NOT_YET_RECRUITING
Conditions: Spinal Cord Injury Cervical|Spastic
Interventions: OTHER: Task Practice combined with Transcutaneous Spinal Cord Stimulation( TcSCS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Evaluation of a Self-Monitoring Intervention to Reduce Safety Behavior in Social Anxiety
Status: COMPLETED
Conditions: Social Anxiety
Interventions: BEHAVIORAL: Safety Behavior Fading for Social Anxiety|BEHAVIORAL: Unhealthy Behavior Fading
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Impact of a Pharmaceutical Care Model on Improving Polycystic Ovary Syndrome
Status: COMPLETED
Conditions: Polycystic Ovary Syndrome
Interventions: OTHER: The PCOS pharmaceutical care service
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Recombinant Human N-Acetylgalactosamine 4-Sulfatase in Patients With MPS VI
Status: COMPLETED
Conditions: Mucopolysaccharidosis VI
Interventions: DRUG: N-acetylgalactosamine 4-sulfatase
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Acalabrutinib in Combination With R-CHOP for Previously Untreated Diffuse Large B-cell Lymphoma (DLBCL)
Status: RECRUITING
Conditions: Diffuse Large B Cell Lymphoma
Interventions: DRUG: R-CHOP|DRUG: R-CHOP + acalabrutinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Role of Rosiglitazone on Pre-Diabetes Mellitus and Coronary Artery Disease
Status: COMPLETED
Conditions: Prediabetes|Coronary Artery Disease|Insulin Resistance|Glucose Intolerance
Interventions: DRUG: placebo tablet|DRUG: rosiglitazone (4 mg)/day
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hyperoxia on Ventilation During Recovery From General Anesthesia
Status: COMPLETED
Conditions: Ventilatory Depression|Postoperative Respiratory Failure
Interventions: OTHER: Oxygen gas
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety Study of Cilostazol to Prevent Reoccurrence of Stroke
Status: COMPLETED
Conditions: Cerebral Infarction
Interventions: DRUG: Cilostazol 200mg/day Oral|DRUG: Aspirin 100mg/day Oral
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Comparison of the Efficacy of Micro-holes vs. Laser-assisted Dermabrasion, for Repigmenting in Vitiligo Skin
Status: COMPLETED
Conditions: Vitiligo - Macular Depigmentation
Interventions: DEVICE: Dermabrasion|DEVICE: Laser placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Enteral Nutrition as Stress Ulcer Prophylaxis in Critically Ill Patients.
Status: COMPLETED
Conditions: Gastrointestinal Hemorrhage|Clostridium Difficile Colitis
Interventions: DRUG: Pantoprazole 40 mg IV daily and tube feed.|OTHER: Placebo and tube feed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Etanercept (Enbrel) in the Treatment of Pemphigus Vulgaris
Status: COMPLETED
Conditions: Pemphigus Vulgaris
Interventions: DRUG: Enbrel (Etanercept)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Fludarabine, Cyclophosphamide, and Rituximab - High Dose Frontline
Status: COMPLETED
Conditions: Chronic Lymphocytic Leukemia
Interventions: DRUG: Fludarabine Phosphate|DRUG: Cyclophosphamide|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Magnesium Sulfate in the Treatment of Bronchiolitis
Status: COMPLETED
Conditions: Bronchiolitis|Magnesium, Abnormal Blood Level
Interventions: DRUG: Magnesium Sulfate|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Imaging Framework for Clinically Testing New Treatments to Prevent Post-traumatic OA
Status: RECRUITING
Conditions: Orthopedic Disorder|Trauma|Ankle Fractures|Post-traumatic Osteoarthritis
Interventions: RADIATION: pedCAT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Automatic Periodic Stimulation and Continuous Electromyography (EMG) for Facial Nerve Monitoring During Parotidectomy
Status: TERMINATED
Conditions: Parotid Gland Disorders
Interventions: DEVICE: APS electrode|DEVICE: Facial Nerve Monitor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Safety and Efficacy of DRM02 in Subjects With Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: DRM02|OTHER: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Symbicort Onset of Action 1
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: budesonide/formoterol (Symbicort)|DRUG: fluticasone/salmeterol (Advair Diskus)|DRUG: albuterol (Ventolin)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Bioactive Glass Ceramics Spacer and PEEK Cages in Posterior Lumbar Interbody Fusion: A Prospective, RCT
Status: COMPLETED
Conditions: Degenerative Lumbar Spinal Stenosis
Interventions: DEVICE: NovoMax, BioAlpha Inc, Seong-nam, Korea|DEVICE: PEEK cage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Prevention of Pegfilgrastim-Induced Bone Pain (PIBP)
Status: COMPLETED
Conditions: Musculoskeletal Complications|Pain|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: naproxen|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Introduction of the Vi Polysaccharide Typhoid Vaccine in Hue City, Central Vietnam
Status: COMPLETED
Conditions: Typhoid|Paratyphoid Fever
Interventions: BIOLOGICAL: Typhoid Vi vaccine|BIOLOGICAL: Hepatitis A (control)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Efficacy of PRF With M-MIST in the Treatment of Intrabony Defects
Status: COMPLETED
Conditions: Periodontitis
Interventions: PROCEDURE: Modified-Minimally Invasive Surgical Technique + PRF|PROCEDURE: Modified-Minimally Invasive Surgical Technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Telerehabilitation vs Clinical Setup Rehabilitation in TKR Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Knee Injuries
Interventions: BEHAVIORAL: Conventional Physiotherapy|OTHER: Traditional Physical Preatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effectiveness of Radon Spa Therapy in Multimodal Rehabilitative Treatment of Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: PROCEDURE: 15 radon(+CO2) baths vs 15 CO2 baths; beside rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Immunotherapy Study for Patients With Stage IV Melanoma
Status: TERMINATED
Conditions: Stage IV Melanoma|Metastatic Melanoma
Interventions: DRUG: HyperAcute®-Melanoma (HAM) Immunotherapy|DRUG: Ipilimumab|DRUG: Pembrolizumab|DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Examining Feasibility and Acceptability of Telemedicine for Substance Use Disorder (SUD)
Status: ACTIVE_NOT_RECRUITING
Conditions: Substance Use Disorders|Substance Use|Substance Dependence
Interventions: BEHAVIORAL: MI-CBT Teletx
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study To Evaluate The Safety, Tolerability And Pk Of Pazopanib Eye Drops In Healthy Adult And Elderly Subjects.
Status: COMPLETED
Conditions: Macular Degeneration|Age-related Macular Degeneration
Interventions: DRUG: Pazopanib eye drops and Allergen Refresh Plus eye drops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy and Safety of TAK-559 Combined With Glyburide in Treating Subjects With Type 2 Diabetes Mellitus.
Status: TERMINATED
Conditions: Diabetes Mellitus
Interventions: DRUG: TAK-559 and glyburide|DRUG: TAK-559 and glyburide|DRUG: Glyburide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Closed-loop Optimized rTMS for Depression
Status: RECRUITING
Conditions: Major Depressive Disorder
Interventions: DEVICE: closed-loop rTMS|DEVICE: open-loop rTMS|DEVICE: sham rTMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: HR Positive, HER2 Negative Advanced Breast Cancer With Progression After Endocrine Therapy
Status: NOT_YET_RECRUITING
Conditions: Solid Tumor, Adult
Interventions: BIOLOGICAL: EOC202|DRUG: albumin-bound paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Atrial Fibrosis Progression in Sleep Apnea Patients: A Pilot Study
Status: RECRUITING
Conditions: Atrial Fibrillation|Obstructive Sleep Apnea
Interventions: DEVICE: Delayed enhancement magnetic resonance imaging (DE-MRI)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Phase II Study Evaluating Intranasal GSK256066 and Fluticasone Propionate in Subjects With Seasonal Allergic Rhinitis (SAR)
Status: COMPLETED
Conditions: Rhinitis, Allergic, Seasonal
Interventions: DRUG: GSK256066|DRUG: fluticasone propionate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Deciphering a Specific Signature of the Immunosenescence Induced in COVID-19+ Patients Versus Rheumatoid Arthritis Patients
Status: COMPLETED
Conditions: SARS-Cov-2 Infection|Rheumatoid Arthritis
Interventions: OTHER: Blood sampling
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Compare the Pharmacokinetics and the Safety Between a Fixed-dose Combination Administration of "BR3005" and Co-administration of "BR3005-1" and "BR3005-2" Under Fasting Conditions in Healthy Adult Volunteers
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: BR3005|DRUG: BR3005-1|DRUG: BR3005-2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Relapse Prevention in First Episode Schizophrenia: a 5 Year Trial
Status: UNKNOWN
Conditions: Schizophrenia
Interventions: BEHAVIORAL: Continuity of specialized care|BEHAVIORAL: Parent groups combined with Continuity of Specialized care|BEHAVIORAL: Discontinuity of care, non specialised care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bowel Preparation for Inpatient Colonoscopy
Status: COMPLETED
Conditions: Gastrointestinal Hemorrhage|Colon Cancer|Diverticulosis
Interventions: DRUG: Go-Lytely|DRUG: Go Lytely
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: DIAGNOSTIC
Clinical trial: Rivaroxaban Plus Aspirin to Manage Recurrent Venous Thromboembolic Events
Status: COMPLETED
Conditions: Venous Thromboembolism|Anticoagulant-induced Bleeding|Venous Thromboses|Pulmonary Embolism
Interventions: DRUG: Rivaroxaban 20 MG [Xarelto]|DRUG: Aspirin 300mg|DRUG: Acenocoumarol Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Paclitaxel, Carboplatin, and Radiation Therapy With or Without Adjuvant Paclitaxel and Carboplatin in Treating Patients With Stage II or Stage III Unresectable Non-Small Cell Lung Cancer
Status: UNKNOWN
Conditions: Lung Cancer
Interventions: DRUG: carboplatin|DRUG: paclitaxel|PROCEDURE: adjuvant therapy|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Methylation Diet and Lifestyle Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Lifestyle|Diet|Healthy
Interventions: OTHER: Diet Recommendations|OTHER: Lifestyle Recommendations|OTHER: Exercise Recommendations|OTHER: Stress Management Recommendations|OTHER: PhytoGanix (tropical fruit flavor)|OTHER: UltraFlora Intensive Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Desidustat in the Treatment of Anemia in CKD on Dialysis Patients
Status: COMPLETED
Conditions: Chronic Kidney Disease Stage 5 on Dialysis
Interventions: DRUG: Desidustat Oral Tablet|DRUG: Epoetin Alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Community Health Worker-led Decision Coaching
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: BEHAVIORAL: Education Counseling Session for PSA Screening|BEHAVIORAL: General Health Counseling Coaching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SCREENING
Clinical trial: Prospective Multicenter Registry on the Endovascular Treatment in Critical Limb Threatening Ischemia With Below the Knee Lesions With Wound, Ischemia, and Foot Infection (WIFI) Assessment
Status: COMPLETED
Conditions: Chronic Limb-threatening Ischemia|Endovascular Therapy
Interventions: DEVICE: Endovascular therapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: When to Start Anti-HIV Drugs in Patients With Opportunistic Infections
Status: COMPLETED
Conditions: HIV Infections|AIDS-Related Opportunistic Infections
Interventions: DRUG: Emtricitabine/tenofovir disoproxil fumarate|DRUG: Lopinavir/ritonavir|DRUG: Stavudine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Phase 2 Study Of VLA15, A Vaccine Candidate Against Lyme Borreliosis, In A Healthy Pediatric And Adult Study Population
Status: ACTIVE_NOT_RECRUITING
Conditions: Lyme Borreliosis
Interventions: BIOLOGICAL: VLA15|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of a Prebiotic Galactooligosaccharide to Reduce Metabolic Syndrome Risk Factors in Overweight Adults
Status: COMPLETED
Conditions: Metabolic Syndrome X
Interventions: DIETARY_SUPPLEMENT: Bimuno|DIETARY_SUPPLEMENT: Maltodextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Primary Tumor Harvest for the Purpose of Possible Use in a Future Clinical Trial in Patients With Ovarian, Fallopian Tube or Primary Peritoneal Cancer
Status: COMPLETED
Conditions: Ovarian Cancer|Peritoneal Cancer|Fallopian Tube Cancer
Interventions: PROCEDURE: Tumor collection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: CETI-ANKLE: Cetilar®️ in Patients With Ankle Injury or Chronic Trauma to the Ankle
Status: ACTIVE_NOT_RECRUITING
Conditions: Ankle Injury or Chronic Trauma to the Ankle
Interventions: DEVICE: Cetilar® (topical cream)|DEVICE: Cetilar Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Vitamin D Supplementation in Healthy Adults in Prolonged Endurance Exercise
Status: ACTIVE_NOT_RECRUITING
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Vitamin D|DIETARY_SUPPLEMENT: Medium-chain triglycerides
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Blood Flow Restriction Training Following Glenoid Labral Repair
Status: WITHDRAWN
Conditions: Glenoid Labrum Tear
Interventions: DEVICE: BFR|OTHER: Standard Rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Autologous Bone Marrow and BMP7 Treatment in the Necrosis in the Femoral Head of the Adult
Status: TERMINATED
Conditions: Aseptic Necrosis of Femur Head
Interventions: PROCEDURE: Drilling|BIOLOGICAL: Bone Marrow +BMP7
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Metvix Photodynamic Therapy (PDT) With Its Vehicle in the Treatment of Photoaged Skin
Status: COMPLETED
Conditions: Photoaged Skin
Interventions: DRUG: Metvix Cream 160 mg/g|DRUG: Metvix Vehicle Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Countermeasures to Reduce Sensorimotor Impairment and Space Motion Sickness Resulting From Altered Gravity Levels
Status: COMPLETED
Conditions: Vestibular
Interventions: DRUG: Promethazine|BEHAVIORAL: Hyper gravity training|DRUG: Placebo|BEHAVIORAL: No hypergravity training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Progressive Resistance Training Versus Relaxation for Breast Cancer Patients During Chemotherapy: Biological Mechanisms and Effects on Fatigue and Quality of Life
Status: COMPLETED
Conditions: Breast Cancer|Cancer-related Fatigue
Interventions: OTHER: Supervised progressive resistance training|OTHER: Supervised progressive muscle relaxation training (Jacobsen method)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Open, Single-center, Safety and Efficacy Study of Conbercept in Patients With Very Low Vision Secondary to Wet Age-related Macular Degeneration (wAMD)
Status: UNKNOWN
Conditions: Very Low Vision Secondary to Wet Age-related Macular Degeneration
Interventions: DRUG: Conbercept
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Denosumab vs. Zoledronic Acid to Treat Bone Metastases in Men With Hormone-refractory Prostate Cancer
Status: COMPLETED
Conditions: Bone Metastases
Interventions: DRUG: zoledronic acid|BIOLOGICAL: denosumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: An Exploratory, Open Label, Multi-Center, Non-Randomized Study of [F-18]VM4-037
Status: COMPLETED
Conditions: Lung Cancer|Squamous Cell Carcinoma|Head and Neck Cancer|Hepatic Carcinoma|Renal Cell Carcinoma
Interventions: DRUG: [F-18] VM4-037
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Management of Progressive Disease in Idiopathic Pulmonary Fibrosis
Status: RECRUITING
Conditions: Progressive Idiopathic Pulmonary Fibrosis
Interventions: DRUG: pirfenidone and nintedanib|DRUG: pirfenidone or nintedanib|DRUG: pirfenidone or nintedanib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Paraorbital-Occipital Alternating Current Stimulation Therapy of Patients With Post-Chiasmatic Lesions
Status: COMPLETED
Conditions: Complete Hemianopia|Incomplete Hemianopia|Scotoma|Quadrantanopia|Stroke|Hemorrhage|Brain Trauma
Interventions: DEVICE: Verum stimulation|DEVICE: Placebo stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Metabolic Response Evaluation of Low-sugar Snack Bars
Status: COMPLETED
Conditions: Pre Diabetes|Diabetes|Obesity
Interventions: OTHER: Control 1|OTHER: Control 2|OTHER: Standard Crokao|OTHER: Low sugar variant 1|OTHER: Low sugar variant 2|OTHER: Low sugar variant 3|OTHER: Low sugar variant 4|OTHER: Low sugar variant 5
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: AMO's Tecnis™ Multifocal Intraocular Lenses (Tecnis MF), Alcon's ReStor Multifocal IOL
Status: UNKNOWN
Conditions: Cataract
Interventions: DEVICE: Tecnis MF|DEVICE: ReSTOR
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Personality Pathology and Cerebral Processing in Eating Disorders
Status: UNKNOWN
Conditions: Eating Disorders
Interventions: OTHER: SCID-I|OTHER: EAT|OTHER: EDI-2|OTHER: SCID-II|OTHER: LoPF|OTHER: HAWIK-IV|DEVICE: fMRI
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Acceleration of Platelet Recovery Following Autologous Peripheral Blood Stem Cell Transplant (PBSC) in Hodgkin, Non-Hodgkin Lymphoma or Multiple Myeloma Patients
Status: TERMINATED
Conditions: Lymphoma, Non-Hodgkin|Hodgkin Disease|Multiple Myeloma
Interventions: DRUG: TXA127|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE