pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: LV Thrombus After Acute AMI: A Randomized Controlled Trial
Status: TERMINATED
Conditions: Ventricular Thrombosis Mural Following Myocardial Infarction
Interventions: DRUG: Absence of vitamin K antagonist
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sirtuin-1 and Advanced Glycation End-products in Postmenopausal Women With Coronary Disease
Status: UNKNOWN
Conditions: Coronary Artery Disease Progression
Interventions: DRUG: Quercetin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Relative Bioavailability of JNJ64041575 Administered as 2 Different New Concept Formulations (Oral Suspension and Tablet) Compared to Their Respective Current Formulations, and to Assess the Effect of Food on the Pharmacokinetics of the 2 New Concept Formulations
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: JNJ-64041575 (oral suspension formulation)|DRUG: JNJ-64041575 (oral tablet formulation )
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radiochemotherapy +/- Durvalumab for Locally-advanced Anal Carcinoma. A Multicenter, Randomized, Phase II Trial of the German Anal Cancer Study Group
Status: ACTIVE_NOT_RECRUITING
Conditions: Anal Cancer|Anal Carcinoma|Anal Cancer Stage III|Anal Cancer Stage II
Interventions: DRUG: Chemotherapy|RADIATION: Radiation|DRUG: Durvalumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Detection and/or Evaluation of Dense Breast Abnormalities Using Tomosynthesis and Digital Mammography
Status: COMPLETED
Conditions: Breast Neoplasms|Breast Abnormalities
Interventions: PROCEDURE: Breast Tomosynthesis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Self-Care for Head and Neck Cancer Survivors With Lymphedema and Fibrosis
Status: COMPLETED
Conditions: Head and Neck Cancer|Lymphedema|Fibrosis
Interventions: OTHER: Usual Care|OTHER: Usual Care plus LEF-SCP|OTHER: Usual Care plus LEF-SCP plus Follow-up
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Assessment of the Functional Outcome and Quality of Life in Sarcoma Patients
Status: RECRUITING
Conditions: Soft Tissue Sarcoma|Bone Sarcoma
Interventions: OTHER: Functional outcome|OTHER: Health related quality of life (HRQoL) assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Phase 2 Study of siG12D LODER in Combination With Chemotherapy in Patients With Locally Advanced Pancreatic Cancer
Status: UNKNOWN
Conditions: Pancreatic Ductal Adenocarcinoma|Pancreatic Cancer
Interventions: DRUG: siG12D-LODER|DRUG: Gemcitabine+nab-Paclitaxel|DRUG: Folfirinox
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Controlling Acute or Early HIV Infection With Antiretroviral Drugs, Without a Candidate Vaccine.As Reported Previously, the Candidate Vaccie Was Not Provided by the Maufacturer as Promised
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Patients elected to take licensed drugs. The vaccine was not provided for evaluation|DRUG: multiple licensed drugs not randomized|DRUG: multiple licensed antiretroviral drugs; not randomized|OTHER: Intended vaccine not provided, Licensed drugs provided, but were not investigated
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy of Postoperative Telerehabilitation in Adolescent Idiopathic Scoliosis
Status: COMPLETED
Conditions: Adolescent Idiopathic Scoliosis
Interventions: PROCEDURE: Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Very Low Nicotine Cigarettes in Smokers With Schizophrenia
Status: COMPLETED
Conditions: Tobacco Dependence
Interventions: OTHER: Very low nicotine content cigarettes|OTHER: standard nicotine content cigarettes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Transcutaneous Vagus Nerve Stimulation for Motor Recovery After Stroke
Status: TERMINATED
Conditions: Stroke|Upper Extremity Paresis
Interventions: DEVICE: Active RAVANS concurrent with arm motor training|DEVICE: Inactive RAVANS concurrent with arm motor training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Induction Chemotherapy in Patients With Locoregionally Advanced Nasopharyngeal Carcinoma
Status: UNKNOWN
Conditions: Nasopharyngeal Carcinoma
Interventions: DRUG: Docetaxel, cisplatin and fluorouracil|RADIATION: Concurrent chemoradiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 22G FNA Needle vs. 22G ProCore Needle
Status: COMPLETED
Conditions: Pancreatic Neoplasm
Interventions: PROCEDURE: 22G ProCore biopsy needle|PROCEDURE: 22G standard FNA needle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Assessment of the Role of the Growth Hormone (GH) Onthe Intestinal Triglyceride-rich-lipoproteins (TRL) Metabolism
Status: UNKNOWN
Conditions: Atherosclerotic Cardiovascular Disease
Interventions: DRUG: Growth Hormone|OTHER: interruption of the traitment with growth hormone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Comparison of the Efficacy of Russian,Aussie Currents With Isokinetic Exercise Patellofemoral Pain Syndrome
Status: COMPLETED
Conditions: Patellofemoral Pain Syndrome
Interventions: DEVICE: Isokinetick Exercise, Aussie Current, Russion Current, Plasebo Electirical Stimulasyon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Losartan/Amlodipine on Hemodynamics Parameters and Arterial Stiffness in Arterial Hypertension
Status: UNKNOWN
Conditions: Hypertension
Interventions: DRUG: Losartan and Amlodipine|DRUG: Losartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating B-Domain Deleted Recombinant Factor VIII (BDDrFVIII, ReFacto AF) in Patients With Hemophilia A Undergoing Elective Major Surgery
Status: COMPLETED
Conditions: Hemophilia A
Interventions: BIOLOGICAL: ReFacto AF
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Pelvic Floor Function and Sexual Life of the Women After Different Type of Hysterectomy
Status: UNKNOWN
Conditions: Quality of Life|Urinary Incontinence|Pelvic Organ Prolapse
Interventions: PROCEDURE: LSH|PROCEDURE: CLSH|PROCEDURE: LAVH
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phase I Clinical Study of HWH340 Tablet in Patients With Advanced Solid Tumors
Status: UNKNOWN
Conditions: Advanced Solid Tumors|HRD|BRCA Mutation
Interventions: DRUG: HWH340 tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Iron Versus Multiple Micronutrient Supplementation on Anemia in Preschool Children of Malaria-Endemic Area
Status: COMPLETED
Conditions: Anemia|Undernutrition
Interventions: DIETARY_SUPPLEMENT: micronutrient supplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Dapagliflozin Plus Pioglitazone in T1DM
Status: RECRUITING
Conditions: Type 1 Diabetes Mellitus
Interventions: DRUG: Pioglitazone 45 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Accelerated Intermittent Theta Burst Stimulation in Unipolar Versus Bipolar Depression
Status: NOT_YET_RECRUITING
Conditions: Depressive Disorder
Interventions: DEVICE: Transmagnetic stimulation|DEVICE: TMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Preventive and Therapeutic Zinc Supplementation Programs Among Young Children
Status: COMPLETED
Conditions: Zinc Deficiency|Diarrhea|Malaria
Interventions: DIETARY_SUPPLEMENT: Daily preventive Zn; placebo treatment|DIETARY_SUPPLEMENT: Therapeutic Zn; daily placebo|DIETARY_SUPPLEMENT: Intermittent Zn; placebo treatment|OTHER: Surveillance control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Topical Antioxidants in Tretment of Photoaging
Status: UNKNOWN
Conditions: Photoaging
Interventions: DRUG: Selenium Amino Acid Chelate (Selenium ACE cream)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective Monocentric Study on the Efficacy of Lidocain Spray for Patient Comfort During Nasogastric Tube Insertion in Enteral Nutrition
Status: COMPLETED
Conditions: Undernutrition
Interventions: DRUG: Lidocaine = group A|DRUG: Group B placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Dose Finding Study of Gadavist in Central Nervous System (CNS) Magnetic Resonance Imaging (MRI)
Status: COMPLETED
Conditions: Brain Diseases|Spinal Cord Diseases
Interventions: DRUG: Gadobutrol~0.03 mmol/kg BW (Gadavist, Gadovist, BAY86-4875)|DRUG: Gadobutrol~0.1 mmol/kg BW (Gadavist, Gadovist, BAY86-4875)|DRUG: Gadobutrol~0.3 mmol/kg BW (Gadavist, Gadovist, BAY86-4875)|DRUG: OptiMARK~0.1 mmol/kg BW
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Innovative Multimodal and Attention Training to Improve Emotion Communication in Veterans With TBI and PTSD
Status: RECRUITING
Conditions: Brain Injury|Post Traumatic Stress Disorder
Interventions: BEHAVIORAL: Multimodal affect recognition training|BEHAVIORAL: Attention Training|BEHAVIORAL: Brain Health Workshop|BEHAVIORAL: National Geographic Movies
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess Insulin Delivery With PaQ® in Patients With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DEVICE: PaQ® Insulin Delivery Device|DRUG: Insulin, Asp(B28)-
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating the Safety, Pharmacokinetics, and Preliminary Efficacy of Orally Administered SM08502 Combined With Hormonal Therapy or Chemotherapy in Subjects With Advanced Solid Tumors
Status: TERMINATED
Conditions: Castration-resistant Prostate Cancer|Non-small Cell Lung Cancer|Colorectal Cancer
Interventions: DRUG: SM08502|DRUG: Abiraterone|DRUG: Prednisone|DRUG: Docetaxel|DRUG: FOLFIRI Protocol|DRUG: Panitumumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Study of ABBV-CLS-7262, Rosuvastatin, and Digoxin in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: ABBV-CLS-7262
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial To Evaluate the Efficacy of Intravenous Iron in Older Adults With Unexplained Anemia
Status: TERMINATED
Conditions: Anemia|Unexplained Anemia (UAE)
Interventions: DRUG: iron sucrose|DRUG: iron sucrose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Consolidation With Loncastuximab Tesirine After a Short Course of Immunochemotherapy in BTKi-treated (or Intolerant) Relapsed/Refractory Mantle Cell Lymphoma Patients.
Status: RECRUITING
Conditions: Relapsed Mantle Cell Lymphoma|Refractory Mantle Cell Lymphoma
Interventions: DRUG: Consolidation with ADCT-402 (loncastuximab tesirine) after salvage immunochemotherapy at standard dose (R-BAC, Rituximab - Bendamustine, Ara-C))|DRUG: Consolidation with ADCT-402 (loncastuximab tesirine) after salvage immunochemotherapy at reduced dose (R-BAC, Rituximab - Bendamustine, Ara-C)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Nurse-coordinated Follow-up Program in Primary Care for People at Risk for T2DM
Status: COMPLETED
Conditions: Pre-diabetes|Cardiovascular Risk Factor|T2DM (Type 2 Diabetes Mellitus)|Primary Health Care
Interventions: BEHAVIORAL: Guided Self Determination
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Autologous Stromal Vascular Fraction in Treatment of Male Androgenic Alopecia
Status: NOT_YET_RECRUITING
Conditions: Androgenic Alopecia
Interventions: PROCEDURE: autologous stromal vascular fraction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Safety and Efficacy of EXPAREL When Administered Via Infiltration Into the TAP vs. Bupivacaine Alone in Subjects Undergoing Elective C-Sections
Status: COMPLETED
Conditions: C-Section|Pain Management
Interventions: DRUG: Exparel + Bupivacaine|DRUG: Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigating the Effects of Cannabidiol on Social Anxiety Disorder
Status: NOT_YET_RECRUITING
Conditions: Phobia, Social
Interventions: DRUG: Cannabidiol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Whey Protein Supplementation and Resistance Training in Older Women With Sarcopenic Obesity.
Status: COMPLETED
Conditions: Body Weight|Healthy
Interventions: DIETARY_SUPPLEMENT: whey protein|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: RTA 408 Lotion in Patients at Risk for Radiation Dermatitis - PRIMROSE
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Omaveloxolone Lotion 0.5%|DRUG: Omaveloxolone Lotion 3%|DRUG: Vehicle Lotion|RADIATION: 3D conformal radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Optimizing Mindfulness and Acceptance Based Behavioral Treatment for Bulimia Nervosa and Binge Eating Disorder
Status: ACTIVE_NOT_RECRUITING
Conditions: Bulimia Nervosa|Bulimia; Atypical|Binge-Eating Disorder|Binge-Eating and Purging Type Anorexia Nervosa|Binge Eating
Interventions: BEHAVIORAL: Behavioral Therapy for Eating Disorders|BEHAVIORAL: MABT: Mindful Awareness|BEHAVIORAL: MABT: Values|BEHAVIORAL: MABT: Emotion Modulation|BEHAVIORAL: MABT: Distress Tolerance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Bioavailability, Pharmacokinetics and Safety of ESR 1150 CL in Healthy Adult Male Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: ESR 1150 CL, Capsule, oral|DRUG: ESR 1150 CL, solution, intravenous
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Electroacupuncture of Scalp Motor Area to Improve Post-Stroke Wrist Dyskinesia
Status: COMPLETED
Conditions: Stroke Sequelae|Movement Disorders
Interventions: OTHER: manual acupuncture|OTHER: electroacupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase III, Double-blind Study to Assess Safety and Efficacy of an RSV Maternal Unadjuvanted Vaccine, in Pregnant Women and Infants Born to Vaccinated Mothers
Status: TERMINATED
Conditions: Respiratory Syncytial Virus Infections
Interventions: BIOLOGICAL: RSV MAT|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: High Flow Therapy for the Treatment of Respiratory Failure in the ED
Status: COMPLETED
Conditions: Acute Respiratory Failure
Interventions: DEVICE: Noninvasive positive pressure ventilation (NIPPV)|DEVICE: Vapotherm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: ETEC Logistics Trial (TREK)
Status: COMPLETED
Conditions: Diarrhea
Interventions: BIOLOGICAL: Heat-Labile Enterotoxin of Escherichia coli (LT)|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Acceptability, Under Use in Real Conditions Of Two Vaginal Moistures Indicated for Women With Vaginal Drying
Status: COMPLETED
Conditions: Vaginal Dryness
Interventions: OTHER: Belamy (vaginal moisturizer)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Role of Neuromodulation Technique In Depression Disorder
Status: NOT_YET_RECRUITING
Conditions: Depressive Disorder, Major
Interventions: DEVICE: rTMS|DEVICE: light therapy|DEVICE: ECT|DEVICE: MST|DRUG: drug therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Study of the Association of Amoxicillin / Clavulanic Acid to Obese Adults
Status: COMPLETED
Conditions: Obesity
Interventions: DRUG: amoxicillin and clavulanic acid|DRUG: amoxicillin and clavulanic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study of MultiStem® in Patients With Acute Leukemia, Chronic Myeloid Leukemia, or Myelodysplasia
Status: COMPLETED
Conditions: Hematologic Malignancies
Interventions: BIOLOGICAL: MultiStem®|BIOLOGICAL: MultiStem®
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety of Two Epidural Catheters in Thoracic Epidural Anaesthesia (TEA)
Status: COMPLETED
Conditions: Anesthesia, Epidural|Paraesthesia
Interventions: DEVICE: Perifix Epidural Anaesthesia Catheter|DEVICE: Perifix Standard|DEVICE: Perifix New
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Early Postoperative Administration of Oxycodone +/- Naloxone and Duration of Epidural Analgesia
Status: COMPLETED
Conditions: Postoperative Pain Management|Radical Cystectomy|Epidural Analgesia|Oral Oxycodone With/Without Naloxone|Return of the Bowel Function
Interventions: DRUG: oxycodone/naloxone|DRUG: Oxycodone|DRUG: Placebo|DEVICE: epidural catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dose Ranging Study of Carbidopa-levodopa
Status: COMPLETED
Conditions: Age-related Macular Degeneration
Interventions: DRUG: Carbidopa-Levodopa, 25 Mg-100 Mg Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mechanistic Effect of Ketones on Cerebral Blood Flow
Status: RECRUITING
Conditions: Cerebrovascular Function|Cerebral Blood Flow
Interventions: DIETARY_SUPPLEMENT: Poikilocapnia|DIETARY_SUPPLEMENT: Normocapnia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: AF-FLOW Registry: This Study is to Evaluate Ablamap Software in Patients Undergoing Ablation for Atrial Fibrillation.
Status: ACTIVE_NOT_RECRUITING
Conditions: Atrial Fibrillation, Persistent|Atrial Fibrillation|Arrhythmias, Cardiac|Heart Diseases|Cardiovascular Diseases|Pathologic Processes
Interventions: DEVICE: Ablamap Software
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Additional Dietary Large Neutral Amino Acids (LNAA) for Improved Symptoms in Adult Classical Phenylktonuria (PKU)
Status: ACTIVE_NOT_RECRUITING
Conditions: Phenylketonurias
Interventions: OTHER: PreKUnil® LNAA Medical Food for PKU
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: HMG-CoA Reductase add-on in Chronic Kidney Disease Patients With Proteinuria
Status: UNKNOWN
Conditions: Chronic Kidney Disease|Proteinuria
Interventions: DRUG: Telmisartan/Rosuvastatin 40/10mg|DRUG: Telmisartan 40mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: LCAR-B38M Cells in Treating Relapsed/Refractory (R/R) Multiple Myeloma
Status: ACTIVE_NOT_RECRUITING
Conditions: Refractory or Relapsed Multiple Myeloma
Interventions: BIOLOGICAL: LCAR-B38M CAR-T cell injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating Combination Therapy Using Autologous Dendritic Cells Pulsed With Antigen Peptides and Nivolumab for Subjects With Advanced Non-Small Cell Lung Cancer
Status: UNKNOWN
Conditions: NSCLC
Interventions: DRUG: Autologous dendritic cells pulsed with antigen
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I Endovenous Administration of Oncolytic Adenovirus ICOVIR-5 in Patients With Advanced or Metastatic Melanoma
Status: COMPLETED
Conditions: Locally Advanced or Metastatic Melanoma
Interventions: BIOLOGICAL: ICOVIR-5
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Allicor on Patients After Coronary Arteria Revascularization Treatment
Status: RECRUITING
Conditions: Myocardial Ischemia|Coronary Artery Bypass Grafting|Coronary Arteriosclerosis|Percutaneous Coronary Revascularization
Interventions: DIETARY_SUPPLEMENT: Allicor|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Sintilimab (IBI308) Combined With Bevacizumab + XELOX Regimen in Metastatic Colorectal Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Colorectal Cancer|RAS Mutation|Microsatellite Stable
Interventions: DRUG: Sintilimab (IBI308)+bevacizumab+oxaliplatin+capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SERETIDE 50/500mcg Versus Tiotropium Bromide On Exacerbation Rates In Severe Chronic Obstructive Pulmonary Disease
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Tiotropium bromide 18mcg|DRUG: Fluticasone propionate/ salmeterol combination 50/500mcg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: The Influence of the 34C>T Variant in the AMPD1 Gene Ischemic Tolerance
Status: COMPLETED
Conditions: AMPD|Ischemic Tolerance
Interventions: DRUG: systemic administration of 99mTc-HYNIC-Annexin A5|BEHAVIORAL: 10 minutes of ischemic handgripping
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: DIAGNOSTIC
Clinical trial: Tilt of the Intraocular Lens in Patients Undergoing Combined Phacoemulsification and Vitrectomy With Airtamponade
Status: COMPLETED
Conditions: Epiretinal Membrane
Interventions: PROCEDURE: airtamponade|PROCEDURE: saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Concordance of Pelvic Organ Mobility Measurements Between the Finite Element Model and the Dynamic Pelvic Floor MRI in Patients Undergoing a Sacrospinofixation Surgery
Status: UNKNOWN
Conditions: Sacrospinofixation|Apical Prolapse
Interventions: OTHER: Dynamic Pelvic Floor MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Acute Myeloid Leukemia At Initial Diagnosis and/or Relapse in Children, Teenagers and Young Adults: Molecular Profiling, Multidrug Testing and MSC Interaction Studies
Status: RECRUITING
Conditions: Acute Myeloid Leukemia|Genetic Predisposition to Disease
Interventions: OTHER: Collection of blood sample of bone marrow (cohort 1)|OTHER: Collection of blood sample of bone marrow (cohort 2 and 3)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Addition of PD-L1 Antibody MEDI4736 to a Taxane-anthracycline Chemotherapy in Triple Negative Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: MEDI4736 (Anti PD-L1)|DRUG: Placebo|DRUG: nab-Paclitaxel|DRUG: Epirubicin|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Immunological Basis for Benralizumab Activity in Chronic Obstructive Pulmonary Disease (COPD)
Status: NOT_YET_RECRUITING
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: DRUG: Benralizumab|OTHER: Benralizumab placebo|OTHER: Comparison (control) group; no intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: RCT Ventralex vs Onlay Mesh in Incisional Hernias
Status: RECRUITING
Conditions: Incisional Hernia of Midline of Abdomen
Interventions: DEVICE: Ventralex|DEVICE: Progrip
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Perioperative Pain Management for Cleft Lip in Children
Status: UNKNOWN
Conditions: Perioperative Complication Pain
Interventions: DRUG: Bupivacain|COMBINATION_PRODUCT: i.v. analgesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Safety of Repurposing Daratumumab for Relapsed or Refractory Autoimmune Antibody Mediated Hemolytic Anemia
Status: ACTIVE_NOT_RECRUITING
Conditions: Hemolytic Anemia
Interventions: DRUG: Daratumumab / Hyaluronidase Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Clinical Trial; Medical vs Bariatric Surgery for Adolescents (13-16 y) With Severe Obesity
Status: ACTIVE_NOT_RECRUITING
Conditions: Obesity|Diabetes|Hypertension|Steatohepatitis|Inflammation
Interventions: PROCEDURE: Laparoscopic Roux-en-Y gastric bypass|PROCEDURE: Intense conservative treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Patient Controlled Positive End-expiratory Pressure on Speech in Tracheostomized Ventilated Patients
Status: COMPLETED
Conditions: Chronic Respiratory Failure
Interventions: DEVICE: Eole 3 ventilator - Resmed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Paclitaxel-binding Albumin and Cisplatin as Neoadjuvant Chemotherapy in Patients With Muscle-Invasive Bladder Cancer
Status: UNKNOWN
Conditions: Bladder Cancer
Interventions: DRUG: Paclitaxel-binding albumin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Apatinib Plus EGFR-TKI as First Line Treatment in Patients With Non-squamous NSCLC Harboring EGFR Mutations
Status: UNKNOWN
Conditions: NSCLC
Interventions: DRUG: Apatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Sport Education on Physical Fitness and Learning Attitude Among Junior High School Students
Status: RECRUITING
Conditions: Physical Fitness
Interventions: BEHAVIORAL: Sport Education Curriculum|BEHAVIORAL: Normal teaching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of Cabergoline for Prevention of Ovarian Hyperstimulation Syndrome (OHSS) in In Vito Fertilization Cycles and Derivation of OHSS Biomarkers
Status: COMPLETED
Conditions: Ovarian Hyperstimulation Syndrome
Interventions: DRUG: Cabergoline|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Reducing Children's Anxiety Using Homeopathic Remedy Before Dental Treatment
Status: COMPLETED
Conditions: Children's Dental Anxiety
Interventions: OTHER: Homeopathic remedy|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Sacro-iliac Joint Arthrodesis or Non-operative Care for Treatment of Chronic Pelvic Pain. A Randomized Study.
Status: COMPLETED
Conditions: Pelvic Pain|Low Back Pain
Interventions: PROCEDURE: Surgery|OTHER: Non-surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Yao Strategy for the Treatment of de Novo Medina 0,1,0 or 0,0,1 Bifurcation Lesion
Status: NOT_YET_RECRUITING
Conditions: Coronary Artery Disease|Bifurcation Lesion
Interventions: PROCEDURE: Drug-coated balloon combined with provisional drug-eluting stent implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Acceptance and Commitment Therapy Versus Active Controls in Improving Psychological Functions of Parents and Children With Adolescent Idiopathic Scoliosis: A Randomized Controlled Trial
Status: RECRUITING
Conditions: Adolescent Idiopathic Scoliosis
Interventions: BEHAVIORAL: 5-week online synchronous ACT intervention|BEHAVIORAL: asynchronous online AIS education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Protocol Memory Deficit in Patients With Obstructive Sleep Apnea Syndrome
Status: COMPLETED
Conditions: Memory Deficit
Interventions: DEVICE: Effective CPAP|DEVICE: Sham CPAP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Image-guided Dosimetry for Interstitial Prostate Brachytherapy
Status: COMPLETED
Conditions: Locally Confined Adenocarcinoma of the Prostate
Interventions: DEVICE: Image Guided Dynamic Dosimetry
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Elucidate the Mechanisms, Development and Effectiveness of Balance Control and Gait Strategy After Mild Traumatic Brain Injury: Develop Innovative Design of Computerized Dual-task Balance Module
Status: RECRUITING
Conditions: Mild Traumatic Brain Injury
Interventions: BEHAVIORAL: Computerized dual-task balance and home program|BEHAVIORAL: Medical consultation and traditional balance training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: ACtive Catheterization for EndovaScular TreatmentS
Status: COMPLETED
Conditions: Unruptured Intracranial Aneurysm|Arteriovenous Cerebral Malformations|Carotid Stenosis
Interventions: DEVICE: GECKO Active Guidewire
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long-term Effects of Transcranial Direct Current Stimulation (tDCS) on Patients With Phantom Limb Pain (PLP)
Status: SUSPENDED
Conditions: Phantom Limb Pain
Interventions: DEVICE: Anodal stimulation of M1 + sham|DEVICE: Sham + Anodal stimulation of M1|DEVICE: Cathodal stimulation of M1 + sham|DEVICE: Sham + Cathodal stimulation of M1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Postoperative Delirium and Its Biomarkers in Elderly Patients Undergoing Non-cardiac and Non-neurosurgery.
Status: RECRUITING
Conditions: Anesthesia|Postoperative Delirium
Interventions: OTHER: The regional cerebral oxygen saturation (rSO2)|OTHER: The glial fibrillary acidic protein (GFAP)|OTHER: The brain-derived-neurotrophic factor (BDNF)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Plasma Glucose Levels With Dexamethasone as Adjuvant to Interscalene Block
Status: WITHDRAWN
Conditions: Shoulder Pain|Injury of Shoulder Region|Disorder of Shoulder|Disorder of Rotator Cuff|Disorder of Tendon of Biceps
Interventions: DRUG: Dexamethasone|DRUG: Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Erlotinib Monotherapy Versus Docetaxel and Cisplatin as Neoadjuvant Therapy in Patients of stageIIIA Lung ca
Status: UNKNOWN
Conditions: Non-small Cell Lung Cancer(NSCLC)
Interventions: DRUG: erlotinib|DRUG: docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 177Lu-P17-087/177Lu-P17-088 in Patients With Metastatic Castration-resistant Prostate Cancer
Status: COMPLETED
Conditions: Metastatic Castration-resistant Prostate Cancer
Interventions: DRUG: 1.1 GBq (30 mCi) of 177Lu-P17-087|DRUG: 1.1 GBq (30 mCi) of 177Lu-P17-088
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Phase II Trial of Individualized Immunotherapy in Early-Stage Unfavorable Classical Hodgkin Lymphoma
Status: RECRUITING
Conditions: Classical Hodgkin Lymphoma
Interventions: DRUG: Tislelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multi-Centre RCT of the Axium® Neurostimulator for the Treatment of Chronic Inguinal Pain Following Surgery
Status: TERMINATED
Conditions: Chronic Inguinal Pain Refractory to Previous Surgical Intervention (Neurectomy)
Interventions: DEVICE: Implantation with the commercially available Axium neurostimulator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects Vitamin D Suppletion on Postprandial Leukocyte Activation
Status: COMPLETED
Conditions: Atherosclerosis|Oxidative Stress|Leukocyte Activation Disorder
Interventions: DRUG: Cholecalciferol|DRUG: Cholecalciferol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Androgen and Growth Hormone on Height and Learning in Girls With Turner Syndrome
Status: COMPLETED
Conditions: Turner Syndrome
Interventions: DRUG: estrogen|DRUG: androgen|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Biliopancreatic Limb Length on Diabetes Following Distal Gastrectomy
Status: COMPLETED
Conditions: Stomach Neoplasm|Diabetes Mellitus, Type 2
Interventions: PROCEDURE: long Roux limb Roux-en-Y reconstruction|PROCEDURE: long biliopancreatic limb Roux-en-Y reconstruction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Specimens From Young Patients With Neuroblastoma
Status: COMPLETED
Conditions: Localized Resectable Neuroblastoma|Localized Unresectable Neuroblastoma|Regional Neuroblastoma|Stage 4S Neuroblastoma
Interventions: OTHER: laboratory biomarker analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Randomized Controlled Trial of Narrative Exposure Therapy Compared to Treatment as Usual for Traumatized Refugees
Status: COMPLETED
Conditions: Posttraumatic Stress Disorder
Interventions: BEHAVIORAL: Narrative Exposure Therapy|BEHAVIORAL: treatment as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Patient Satisfaction and Complications With the New Titan® One Touch Release (OTR) Penis Prosthesis
Status: COMPLETED
Conditions: Erectile Dysfunction|Intraoperative Complications|Postoperative Complications
Interventions: OTHER: Erectile Dysfunction Inventory of Treatment Satisfaction (EDITS) Questionnaire
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Milnacipran on Widespread Mechanical and Thermal Hyperalgesia of Fibromyalgia Patients
Status: COMPLETED
Conditions: Fibromyalgia
Interventions: DRUG: Milnacipran
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Preventing Isthmocele After Cesarean Section
Status: COMPLETED
Conditions: Cesarean Section Complications|Uterine Scar Diverticulum|Uterine Scar From Previous Cesarean Delivery
Interventions: PROCEDURE: Non-Locking Uterine Closure|PROCEDURE: Locked Uterine Closure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of T900607-Sodium in Previously Treated Patients With Non-Hodgkin's Lymphoma.
Status: TERMINATED
Conditions: Non-Hodgkin's Lymphoma
Interventions: DRUG: intravenous T900607-sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: H. Pylori Eradication With Argon Plasma During Endoscopy
Status: NOT_YET_RECRUITING
Conditions: Helicobacter Pylori Infection|Helicobacter Pylori|Helicobacter Pylori Gastrointestinal Tract Infection|H. Pylori Infection|H. Pylori Gastrointestinal Disease
Interventions: PROCEDURE: HEAPE|PROCEDURE: Pre-HEAPE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dexmedetomidine for Postoperative Analgesia After Bariatric Surgery
Status: COMPLETED
Conditions: Obesity|Sleep Apnea|Diabetes|Hypertension
Interventions: DRUG: Dexmedetomidine|DRUG: Morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective Trial for Examining Hematuria Using Computed Tomography
Status: COMPLETED
Conditions: Urothelial Carcinoma|Renal Cell Carcinoma|Renal Cyst|Renal Stone
Interventions: DIAGNOSTIC_TEST: CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Local Infiltration Analgesia in Major Spine Surgery With Ropivacaine Versus Placebo
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: DRUG: Ropivacaine 0.5 %|DRUG: Isotonic NaCl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Acne Scars With Erbium:Yttrium Aluminum Garnet (Er:YAG) Laser Examined Under OCT
Status: WITHDRAWN
Conditions: Acne Vulgaris
Interventions: DEVICE: Alma - Harmony XL Laser
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Efficacy of Two Erythropoietin Drug in Participants With Secondary Anemia to Chronic Kidney Disease.
Status: TERMINATED
Conditions: Chronic Kidney Disease|Anemia
Interventions: DRUG: Epoetin alpha|DRUG: Eprex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Immunoregulatory Effects of Immunoglobulin Induction Therapy in Renal Transplant Recipients
Status: COMPLETED
Conditions: Renal Failure, Chronic|Renal Transplantation
Interventions: DRUG: intravenous immunoglobulins (IVIG)|PROCEDURE: kidney transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Tricuspid Valve Regurgitation in Patients Undergoing Left Ventricular Assist Device Implantation Study
Status: COMPLETED
Conditions: Tricuspid Valve Insufficiency|Right Heart Failure|Heart Failure
Interventions: PROCEDURE: Tricuspid valve repair or replacement|OTHER: Medical management of tricuspid regurgitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: E-CLAIR: Efficiency and Cost-effectiveness of Artificial Intelligence Based Diabetic Retinopathy Screening in Flanders
Status: UNKNOWN
Conditions: Diabetic Retinopathy
Interventions: DEVICE: deep learning|DIAGNOSTIC_TEST: remote grading of fundus images|DIAGNOSTIC_TEST: gold standard
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: EUS Guided Cyanoacrylate Injection vs Endoscopic Variceal Band Ligation for Prevention of Rebleeding in Patients With Hepatocellular Carcinoma and Esophageal Variceal Bleeding
Status: ACTIVE_NOT_RECRUITING
Conditions: EUS Guided Cyanoacrylate Injection|Endoscopic Variceal Band Ligation|Hepatocelular Carcinoma|Esophageal Variceal Bleeding
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical Evaluation of the PROGENSA(Registered Trademark) Prostate Cancer Gene 3 (PCA3) Assay in Men With a Previous Negative Biopsy Result
Status: COMPLETED
Conditions: Prostatic Neoplasms
Interventions: OTHER: PCA3 Assay
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy and Safety of Shea Nut Oil in Hemophilic Arthropathy
Status: TERMINATED
Conditions: Hemophilia|Hemophilic Arthropathy
Interventions: DIETARY_SUPPLEMENT: shea nut oil extract|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Brief Cognitive Behavioral Therapy Replication Trial
Status: ENROLLING_BY_INVITATION
Conditions: Suicide, Attempted|Suicidal Ideation
Interventions: BEHAVIORAL: Brief Cognitive Behavioral Therapy (BCBT)|BEHAVIORAL: Present-Centered Therapy (PCT)|BEHAVIORAL: Treatment as Usual (TAU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Outcomes and Biomarkers in Patients With Stage 0-IV Melanoma in Real Clinical Practice
Status: RECRUITING
Conditions: Melanoma|Melanoma (Skin)|Melanoma, Uveal|Melanoma Stage IV|Melanoma Stage III|Melanoma, Stage II|Melanoma in Situ|Melanoma, Ocular
Interventions: DRUG: surgery (any volume) and / or pharmaceuticals treatment initiated or planned or only dynamic observation, in accordance with current clinical guidelines
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety of TAK-385 in the Treatment of Uterine Fibroids
Status: COMPLETED
Conditions: Uterine Fibroids
Interventions: DRUG: TAK-385|DRUG: TAK-385|DRUG: TAK-385|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT