pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: An Open-Label Study of the Safety of Interferon Gamma-1b in Patients With IPF
Status: TERMINATED
Conditions: Idiopathic Pulmonary Fibrosis|Pulmonary Fibrosis|Lung Disease
Interventions: DRUG: Interferon gamma-1b
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bad Breath Response to Tongue Scraper and Rinses
Status: COMPLETED
Conditions: Halitosis
Interventions: DRUG: Chlorine dioxide and scraper|DRUG: Chlorhexidine gluconate and scraper
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 (First in Human) Randomized, Double-blind, Placebo-controlled SAD, MAD Study With Oral REM0046127
Status: COMPLETED
Conditions: Alzheimer Disease
Interventions: DRUG: REM0046127|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of Digital Care-plan for Improving Long-term Care 2.0 Service Activation Proportion
Status: COMPLETED
Conditions: Digital Care-plan|Long-term Care|Activation Proportion|Case Management, APP(Application)
Interventions: COMBINATION_PRODUCT: APP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: High-Dose 3-Dimensional Conformal Radiation Therapy in Treating Patients With Inoperable Stage I, Stage II, or Stage IIIA Non-Small Cell Lung Cancer
Status: TERMINATED
Conditions: Lung Cancer
Interventions: RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Visilizumab Versus Placebo in Subjects With Intravenous Steroid-refractory Ulcerative Colitis Previously Responsive in a Visilizumab Study
Status: TERMINATED
Conditions: Ulcerative Colitis
Interventions: DRUG: visilizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Metabolic Syndrome and Persistent Shoulder Pain 1 Year After Primary Diagnosis
Status: ACTIVE_NOT_RECRUITING
Conditions: Shoulder Pain|Metabolic Syndrome
Interventions: OTHER: Non-surgical treatment such as physiotherapy, exercise, corticosteroid injection, medication, acupuncture|PROCEDURE: Surgery
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Omega-3-fatty Acids on Age-related Macular
Status: COMPLETED
Conditions: Aged Macular Degeneration
Interventions: DIETARY_SUPPLEMENT: Omega 3|OTHER: Olive Oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Home Hemodialysis Assisted by a Nurse for Arterio-venous Fistula Cannulation
Status: UNKNOWN
Conditions: Hemolysis|Cannulation|Arteriovenous Fistula|Nurse's Role
Interventions: PROCEDURE: assisted home hemodialysis patients
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect Of Resistive Capactive Electrical Transfer Therapy In Difficult-to-heal Wounds
Status: NOT_YET_RECRUITING
Conditions: Difficult-to-heal Wounds
Interventions: DEVICE: OKTO|DEVICE: Standard clinical procedures
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy of Topical Cyclosporin for Ocular Rosacea
Status: COMPLETED
Conditions: Rosacea
Interventions: DRUG: Cyclosporine 0.05%|DRUG: Ocular lubricant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Relationship Between Modified Closed Kinetic Chain Upper Extremity Stability Test and Shoulder Endurance Test in Young Active and Sedentary Individuals
Status: RECRUITING
Conditions: Healthy
Interventions: DIAGNOSTIC_TEST: Closed Kinetic Chain Upper Extremity Stability Test (CKCUEST), and Posterior Shoulder Endurance Test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Protocolized Care for Early Septic Shock
Status: COMPLETED
Conditions: Sepsis|Severe Sepsis|Septic Shock
Interventions: PROCEDURE: Early Goal Directed Therapy (EGDT)|PROCEDURE: Protocolized Standard Care (PSC)|PROCEDURE: Usual Care (UC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improving Delivery of Mental Health Services for Patients With Drug Use and Other Behavioral and Emotional Problems
Status: COMPLETED
Conditions: Study Focusing on Integrated Versus Non-integrated Psychiatric Care in|Opioid-dependent and Methadone Treated Patients With Other Psychiatric|Diagnoses
Interventions: BEHAVIORAL: Counseling compliance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EMBRACE-SC: Observational Study of Subcutaneous (SC) Tocilizumab Alone or in Combination With Conventional Disease-Modifying Antirheumatic Drugs (cDMARDs) in Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: BIOLOGICAL: Tocilizumab
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of I/R Injuries by Pringle Manoeuvre on the Prognosis of HCC Patients After Curative Hepatectomy
Status: COMPLETED
Conditions: Hepatocellular Carcinoma
Interventions: PROCEDURE: curative resection without Pringle|PROCEDURE: curative resection with Pringle manoeuvre
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Phantom Limb Pain by Intensive Visual Stimulation Therapy
Status: NOT_YET_RECRUITING
Conditions: Phantom Limb Pain
Interventions: DEVICE: Intensive Visual Stimulation (IVS)|OTHER: Usual Care (UC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Green Tea and Reduction of Breast Cancer Risk
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Green tea extract supplement|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Extracorporeal Photopheresis (ECP) With Methoxsalen for Chronic Graft Versus Host Disease (cGVHD)
Status: COMPLETED
Conditions: Chronic Graft Versus Host Disease
Interventions: DRUG: ECP Methoxsalen|DRUG: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Negative Pressure Wound Therapy in Groin Dissection
Status: UNKNOWN
Conditions: Neoplasm Metastasis|Secondary Malignant Neoplasm of Lymph Node|Non-healing Surgical Wound (Disorder)|Skin Neoplasms
Interventions: DEVICE: PICO™
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Metabolically Armed CD19 CAR-T Cells (Meta10-19) in the Treatment of Relapsed and/or Refractory CD19-positive B Cell Hematological Malignancies Clinical Research
Status: RECRUITING
Conditions: Acute Lymphoblastic Leukemia|Non-hodgkin Lymphoma
Interventions: DRUG: Metabolically Armed CD19 CAR-T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cardiac Rehabilitation for Heart Event Recovery (HER)
Status: COMPLETED
Conditions: Myocardial Ischemia|Acute Coronary Syndrome|Heart Disease|Coronary Artery Disease
Interventions: BEHAVIORAL: Cardiac Rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Radial Head Arthroplasty A Clinical and Radiological Comparison of Monopolar and Bipolar Radial Head Arthroplasty
Status: COMPLETED
Conditions: Radial Head Fracture|Elbow Fracture|Arthroplasty Complications
Interventions: PROCEDURE: Type of radial head arthroplasty
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Treatment of Vasospasm of Aneurysmal Subarachnoid Hemorrhage With Intrathecal Nicardipine - FAST-IT Trial
Status: RECRUITING
Conditions: Aneurysmal Subarachnoid Hemorrhage|Vasospasm
Interventions: DRUG: Intrathecal Nicardipine|OTHER: No intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Development of MRI Protocols and Associated Explorations (EEG, NIRS) in Voluntary Patients
Status: COMPLETED
Conditions: Magnetic Resonance Imaging
Interventions: RADIATION: Magnetic resonance imaging|DEVICE: EEG|DEVICE: NIRS
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of Blood and Urine Samples in Patients With Newly Diagnosed Localized Prostate Cancer Treated With Hormone Therapy and Radiation Therapy. ICORG 06-15
Status: UNKNOWN
Conditions: Prostate Cancer
Interventions: OTHER: Non-interventional|GENETIC: Protein expression analysis|GENETIC: Proteomic profiling|OTHER: Laboratory biomarker analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Lysophosphatidic Acid / Autotaxin Axis in Rheumatoid Lung Disease
Status: UNKNOWN
Conditions: Rheumatoid Arthritis
Interventions: OTHER: Quantitative ATX and LPA determination in plasma and sputum
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy of Music on Reduction of Sedative Drugs in Mechanically Ventilated Intensive Care Unit Patients
Status: UNKNOWN
Conditions: Sedative Drug Consumption|Mechanically Ventilated ICU Patients
Interventions: DEVICE: MP3 music program listening
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of a Physical Activity Intervention for Pre-frail Older Adults With Chronic Pain.
Status: COMPLETED
Conditions: Frailty|Chronic Pain|Old Age; Debility
Interventions: OTHER: Physical Activity Program|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Persistence of a GBS Antibody in Women Previously Immunized With a GBS Vaccine
Status: COMPLETED
Conditions: Group B Streptococcus (GBS) Disease
Interventions: BIOLOGICAL: Group B streptococcus (GBS) vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: UVB-Induced MVP Release in Human Skin
Status: COMPLETED
Conditions: Ultraviolet B Radiation|Microvesicle Particles
Interventions: DIETARY_SUPPLEMENT: Vitamin C|DIETARY_SUPPLEMENT: Vitamin E
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical, Genetic and Epigenetic Characterization of Patients With FSHD Type 1 and FSHD Type 2
Status: COMPLETED
Conditions: Muscular Dystrophy, Facioscapulohumeral
Interventions: BIOLOGICAL: Blood test
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of BCMA CAR-T in Multiple Myeloma
Status: UNKNOWN
Conditions: Multiple Myeloma
Interventions: DRUG: Fludarabine|DRUG: Cyclophosphamide|BIOLOGICAL: BCMA CAR-T
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Observational Study to Evaluate Physical Activity, Bleeding Incidence and Health Related Quality of Life, in Participants With Haemophilia A Without Inhibitors Receiving Standard of Care Treatment
Status: COMPLETED
Conditions: Severe Hereditary Factor VIII Deficiency Disease Without Inhibitor|Moderate Hereditary Factor VIII Deficiency Disease Without Inhibitor|Haemophilia A
Interventions: DRUG: Standard of Care for Haemophilia A
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Immunogenicity of COVID-19 Vaccines in Tuberculosis Patients
Status: ENROLLING_BY_INVITATION
Conditions: Covid-19 Pandemics|Tuberculosis
Interventions: BIOLOGICAL: Pfizer-BioNTech COVID-19 vaccine|BIOLOGICAL: AstraZeneca vaccine|BIOLOGICAL: Janssen Ad26.COV2.S COVID-19 vaccine
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Mid and Standard Frequency Ventilation in Infants With Respiratory Distress Syndrome
Status: ACTIVE_NOT_RECRUITING
Conditions: Ventilator-Induced Lung Injury|Respiratory Distress Syndrome|Bronchopulmonary Dysplasia|Preterm Infant
Interventions: DEVICE: Mid frequency ventilation|DEVICE: Standard frequency ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimal Management of Rheumatoid Arthritis Patients Requiring Biologic Therapy
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: etanercept or adalimumab|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Initial Experience in Brazilian Single Center With High Intensity Focalized Ultrasound (HIFU) Prostate Cancer Therapy: Morbidity, Oncological and Functional Outcomes.
Status: UNKNOWN
Conditions: Prostate Cancer|Prostate Adenocarcinoma|Transrectal High Intensity Focused Ultrasound
Interventions: DEVICE: HIFU
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Telerehabilitation for Anterior Cruciate Ligament Reconstruction - TAR Program in Adolescents
Status: RECRUITING
Conditions: Telerehabilitation|Anterior Cruciate Ligament Injuries|Anterior Cruciate Ligament
Interventions: DEVICE: Telerehabilitation TAR program using a mobile application|OTHER: Standard rehabilitation sessions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Full Thickness Mucoperiosteal Flap Versus Low Level Laser in Orthodontic Tooth Movement Acceleration
Status: COMPLETED
Conditions: Mesial Movement of Teeth
Interventions: PROCEDURE: elevation of full thickness mucoperiosteal flap|DEVICE: low level laser therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Thalidomide Combined With R-CHOP in Newly Diagnosed，Untreated Double-expressor Diffuse Large B-Cell Lymphoma Patients
Status: UNKNOWN
Conditions: Thalidomide
Interventions: DRUG: Thalidomide combined with R-CHOP|DRUG: R-CHOP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of a Homoeopathic Complex on Blood Pressure in Refractory Hypertension
Status: COMPLETED
Conditions: Essential Hypertension
Interventions: OTHER: 20% ethanol|OTHER: Homoeopathic complex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Crestal Sinus Technique Using Autologous Fibrin Glue Vs Sticky Bone With Simultaneous Implant Insertion.
Status: ACTIVE_NOT_RECRUITING
Conditions: Missed Upper Posterior Teeth
Interventions: PROCEDURE: Maxillary sinus augmentation using autologous fibrin glue with simultaneous implant placement|PROCEDURE: Maxillary sinus augmentation using mixture of autologous fibrin glue with bone graft with simultaneous implant placement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of ECMO in Acute Myocardial Infarction Cardiogenic Shock
Status: SUSPENDED
Conditions: Acute Myocardial Infarction|Cardiogenic Shock
Interventions: DEVICE: VA-ECMO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Pharmacokinetics and Pharmacodynamics of GSK461364 in Subjects With Non-Hodgkins Lymphoma
Status: COMPLETED
Conditions: Lymphoma, Non-Hodgkin
Interventions: DRUG: GSK461364
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Hemopure® to Enhance Tissue Preservation During Cardiopulmonary Bypass Surgery
Status: UNKNOWN
Conditions: Coronary Artery Disease
Interventions: DRUG: HBOC-201 (hemoglobin glutamer-250 bovine)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Observational Study of Type II Diabetics Treated With Dual Therapy With or Without Sitagliptin (Januvia®/Xelevia®, MK-0431-201)
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Metformin|DRUG: Sitagliptin|DRUG: Sulfonylurea|DRUG: Antihyperglycemic Medication
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Development of a Health-Related Symptom Index for Participants With and Either Treated or Monitored for Anal High-Grade Squamous Intraepithelial Lesions
Status: COMPLETED
Conditions: High Grade Anal Canal Squamous Intraepithelial Neoplasia|Human Immunodeficiency Virus
Interventions: OTHER: Interview|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Icosabutate - A Phase I, Single Oral Dose, Safety, Tolerability and Pharmacokinetic Study in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: icosabutate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Trial Comparing Adjuvant Chemotherapy With Gemcitabine Versus mFolfirinox to Treat Resected Pancreatic Adenocarcinoma
Status: COMPLETED
Conditions: Pancreatic Adenocarcinoma (Ductal Adenocarcinoma)
Interventions: DRUG: mFolfirinox|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Is Myopathy Part of Statin Therapy (IMPOSTER-16)
Status: WITHDRAWN
Conditions: Myopathic Conditions
Interventions: DRUG: cellulose placebo vs. atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effect of Semiconductor Knee Sleeves on Pain in Osteoarthritis of the Knee.
Status: RECRUITING
Conditions: Osteo Arthritis Knee
Interventions: DEVICE: Semiconductor Knee Sleeves|DEVICE: Cotton Knee Sleeves (Placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Capecitabine, Oxaliplatin, Docetaxel and Atezolizumab in Resectable Gastric and GE-junction Cancer (PANDA)
Status: UNKNOWN
Conditions: Stomach Cancer|Gastro Esophageal Junction Cancer
Interventions: DRUG: Atezolizumab|DRUG: Capecitabine|DRUG: Oxaliplatin|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Saliva Substitute Mouthwash in NPC Survivors With Xerostomia: A Randomized Controlled Trial
Status: COMPLETED
Conditions: Xerostomia, Hyposalivation, Saliva Substitute, Radiation-induced Toxicity, Nasopharyngeal Cancer
Interventions: DIAGNOSTIC_TEST: Summated Xerostomia Inventory|DIAGNOSTIC_TEST: Sialometry
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Rhythmic Auditory Stimulation on Movements in Individuals at Risk for Psychotic Onset and Schizophrenia Patients
Status: UNKNOWN
Conditions: Schizophrenia|Psychosis|Parkinsonism|Dyskinesias
Interventions: BEHAVIORAL: Rhythmic auditory stimulation (RAS) for schizophrenia patients|BEHAVIORAL: No RAS for schizophrenia patients|BEHAVIORAL: RAS for at-risk individuals|BEHAVIORAL: No RAS for at-risk individuals
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Aortix CRS Pilot Study
Status: COMPLETED
Conditions: Heart Failure; With Decompensation|Cardiorenal Syndrome|Cardio-Renal Syndrome|Heart Failure|Heart Failure，Congestive|Heart Failure, Systolic|Heart Failure, Diastolic
Interventions: DEVICE: Aortix System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Beetroot Juice Supplementation Dose on Neuromuscular Performance During Resistance Exercise
Status: RECRUITING
Conditions: High Nitrate Dose|Moderate Nitrate Dose|Low Nitrate Dose|Nitrate-depleted Dose
Interventions: DIETARY_SUPPLEMENT: BR-HIGH|DIETARY_SUPPLEMENT: BR-MOD|DIETARY_SUPPLEMENT: BR-LOW|DIETARY_SUPPLEMENT: PL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Cancer Genome Study Using Samples From Patients With Stage I or Stage II Non-Small Cell Lung Cancer Treated on Clinical Trial ACOSOG-Z0030
Status: COMPLETED
Conditions: Lung Cancer
Interventions: GENETIC: DNA analysis|GENETIC: RNA analysis|GENETIC: microarray analysis|GENETIC: mutation analysis|GENETIC: polymorphism analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Identifying the Brain Substrates of Hypoglycemia Unawareness in Type 1 Diabetes
Status: COMPLETED
Conditions: Hypoglycemia
Interventions: DRUG: Insulin|DRUG: Glucose|DRUG: Potassium phosphate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Allogeneic Mesenchymal Stem Cells for the Critical Limb Ischemia Therapy
Status: UNKNOWN
Conditions: Critical Limb Ischemia
Interventions: BIOLOGICAL: Mesenchymal stem cells|BIOLOGICAL: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Double-Blind Comparison of the Efficacy of Continued Zidovudine Versus 2',3'-Dideoxyinosine (ddI) (BMY-40900) for the Treatment of Patients With AIDS or AIDS-Related Complex and Increasing Symptomatology Despite Treatment With Zidovudine
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Zidovudine|DRUG: Didanosine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Emodepside in Adults Infected With Strongyloidiasis Stercoralis
Status: RECRUITING
Conditions: Strongyloides Stercoralis Infection|Strongyloidiasis
Interventions: DRUG: Emodepside
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Research Study in Patients With Advanced Ovarian Epithelial Cancer
Status: WITHDRAWN
Conditions: Ovarian Serous Cystadenocarcinoma|Ovarian Serous Surface Papillary Adenocarcinoma|Stage IIIA Ovarian Cancer|Stage IIIB Ovarian Cancer|Stage IIIC Ovarian Cancer|Stage IV Ovarian Cancer
Interventions: GENETIC: Comparative Genomic Hybridization|OTHER: Laboratory Biomarker Analysis|GENETIC: Polymerase Chain Reaction
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Low Dose Growth Hormone in Obese PCOS Women
Status: WITHDRAWN
Conditions: Polycystic Ovary Syndrome
Interventions: DRUG: Nutropin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Children With Aluminium Contact Allergy: Cutaneous Exposure Study
Status: COMPLETED
Conditions: Contact Dermatitis|Contact Allergy|Aluminum Allergy
Interventions: OTHER: Repeated open application test
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: 24-hr IOP With Travoprost/Timolol Compared With Latanoprost/Timolol in XFG
Status: COMPLETED
Conditions: Glaucoma
Interventions: DRUG: treatment with latanoprost/timolol fixed combination|DRUG: latanoprost/timolol fixed combination drops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Safety and Efficacy of Two Types of Circular Column Modulated Lenses for Delaying the Progression of Myopia
Status: ACTIVE_NOT_RECRUITING
Conditions: Myopia
Interventions: DEVICE: Circular cylindrical mirror modulated frame glasses (compact)|DEVICE: Circular cylindrical mirror modulated frame glasses (strong defocus)|DEVICE: single vision frame glasses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing the Influence of a Mindfulness-based Stress Reduction Program vs. Routine Management on Psychological Variables and Biological Markers Related to Immuno-inflammation Associated With Psychological Stress in Caregivers of Patients With Severe Psychiatric Disorders
Status: RECRUITING
Conditions: Psychiatry|Caregivers|Mindfulness
Interventions: OTHER: stress reduction program based on mindfulness|BIOLOGICAL: venipunctures|OTHER: psychometric questionnaires
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Clinical Study to Evaluate the Efficacy and Safety of Givinostat in Ambulant Patients With Becker Muscular Dystrophy
Status: COMPLETED
Conditions: Becker Muscular Dystrophy
Interventions: DRUG: givinostat|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tideglusib vs. Placebo in the Treatment of Adolescents With Autism Spectrum Disorders
Status: COMPLETED
Conditions: Autism Spectrum Disorders
Interventions: DRUG: Tideglusib|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Extended Therapeutic Effect of 35kDa Hyaluronan Fragment Injection in Patients With Chronic Pain Caused by Myofascial Pain Syndrome
Status: ENROLLING_BY_INVITATION
Conditions: Chronic Wound|Myofascial Pain Syndrome
Interventions: DRUG: HA35 injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating a 13-valent Pneumococcal Conjugate Vaccine in Preterm Compared to Term Infants.
Status: COMPLETED
Conditions: 13-valent Pneumococcal Vaccine|Premature Birth|Immunization|Safety
Interventions: BIOLOGICAL: 13-valent pneumococcal conjugate vaccine|BIOLOGICAL: 13-valent pneumococcal conjugate vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Letrozole in Preventing Breast Cancer in Postmenopausal Women With a BRCA1 or BRCA2 Mutation
Status: COMPLETED
Conditions: brca1 Mutation Carrier|brca2 Mutation Carrier|Breast Cancer|Hereditary Breast/Ovarian Cancer (brca1, brca2)
Interventions: DRUG: letrozole|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: S0217, Adjuvant Cisplatin and Docetaxel After Complete Resection Stage III or IV Head and Neck Cancer
Status: WITHDRAWN
Conditions: Head and Neck Cancer
Interventions: DRUG: cisplatin|DRUG: docetaxel|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Recognition of Early Pulmonary Structural Changes by Using Real-time High Fidelity Expiratory CO2 Analysis
Status: RECRUITING
Conditions: COPD|ILD
Interventions: DIAGNOSTIC_TEST: single high-fidelity expiratory CO2 analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Temozolomide in Relapsed or Advanced Anaplastic Oligodendroglioma and Oligoastrocytoma: Single-arm, Phase II Trial
Status: COMPLETED
Conditions: Anaplastic Oligodendroglioma|Anaplastic Oligoastrocytoma
Interventions: DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The TRIABETES - ARMMS-T2D Study: A Randomized Trial to Compare Surgical and Medical Treatments for Type 2 Diabetes
Status: ACTIVE_NOT_RECRUITING
Conditions: Type 2 Diabetes Mellitus|Obesity
Interventions: PROCEDURE: Roux-en-Y Gastric Bypass Surgery|PROCEDURE: Laparoscopic Adjustable Gastric Banding|BEHAVIORAL: Lifestyle Weight Loss Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Hypofractionated Radiotherapy Strategy After Surgery of Skin Carcinomas in Older Patients
Status: RECRUITING
Conditions: Skin Cancer, Non-Melanoma
Interventions: OTHER: Surgery with additional moderate hypofractionation RT (15 fractions)|OTHER: Surgery alone, without radiation post surgery|RADIATION: Surgery with extreme hypo fractionation treatment (HF)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Endorectal Cooling During RARP to Minimize Trauma and Promote Earlier Return to Continence
Status: COMPLETED
Conditions: Incontinence
Interventions: DEVICE: UroCool (Local cooling/hypothermia)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of NV-101 for Efficacy, Pharmacodynamics, and Safety in Dental Patients Undergoing Maxillary Procedures
Status: COMPLETED
Conditions: Anesthesia, Dental
Interventions: DRUG: Phentolamine Mesylate (NV-101)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Hemostatic Gelatin Sponge Versus Collagen Matrix in Alveolar Ridge Preservation
Status: WITHDRAWN
Conditions: Changes in Soft Tissue Height
Interventions: DEVICE: test group: collagen matrix (Mucograft Seal®, Geistlich Pharma AG, Wolhusen, Switzerland)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tailored Treatment of Permanent Atrial Fibrillation
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: PROCEDURE: Medtronic Cardiac Ablation System|DRUG: Class I or III Antiarrhythmic Medications
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 1/2 Study of INCB001158 in Combination With Chemotherapy in Subjects With Solid Tumors
Status: COMPLETED
Conditions: Biliary Tract Cancer (BTC)|Colorectal Cancer (CRC)|Endometrial Cancer|Gastroesophageal Cancer (GC)|Ovarian Cancer|Solid Tumors
Interventions: DRUG: INCB001158|DRUG: Oxaliplatin|DRUG: Leucovorin|DRUG: 5-Fluorouracil|DRUG: Gemcitabine|DRUG: Cisplatin|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non-invasive Evaluation of Upper and Lower Body Function With Showmotion
Status: RECRUITING
Conditions: Osteoarthritis, Hip|Osteoarthritis, Knee|Osteoarthritis, Spine
Interventions: DEVICE: Showmotion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Post-Approval Clinical Trial Comparing the Long Term Safety and Effectiveness Coflex vs. Fusion to Treat Lumbar Spinal Stenosis
Status: COMPLETED
Conditions: Spinal Stenosis
Interventions: PROCEDURE: Decompression|DEVICE: Posterolateral Fusion and Implantation of Pedicle Screws|DEVICE: Implantation of coflex Interlaminar Technology
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Health Promotion and Fitness for Younger and Older Adults With SMI
Status: COMPLETED
Conditions: Schizophrenia|Bipolar Disorder|Schizoaffective Disorder
Interventions: BEHAVIORAL: In SHAPE|BEHAVIORAL: Fitness Club Membership
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of Intravenous (iv) Mircera in Hemodialysis Patients With Chronic Renal Anemia
Status: COMPLETED
Conditions: Anemia
Interventions: DRUG: methoxy polyethylene glycol-epoetin beta [Mircera]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunotherapy After Surgery for People Who Have No Remaining Cancer Cells After Standard Treatment for Early-Stage Non-Small Cell Lung Cancer, INSIGHT Trial
Status: NOT_YET_RECRUITING
Conditions: Lung Non-Small Cell Carcinoma|Stage II Lung Cancer AJCC v8|Stage IIIA Lung Cancer AJCC v8|Stage IIIB Lung Cancer AJCC v8
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|BIOLOGICAL: Durvalumab|OTHER: Patient Observation|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Ranibizumab for Diabetic Macular Edema
Status: COMPLETED
Conditions: Diabetic Macular Edema
Interventions: DRUG: Ranibizumab|DRUG: Ranibizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Programmed Intermittent Epidural Bolus For Laboring Obstetrical Women
Status: COMPLETED
Conditions: Labor Pain
Interventions: DRUG: Bupivacaine 0.08% - fentanyl 2mcg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Effect of Nutritional Intervention and Olive Oil in Severe Obesity
Status: COMPLETED
Conditions: Severe Obesity
Interventions: BEHAVIORAL: Nutritional intervention|OTHER: Nutritional intervention plus olive oil|DIETARY_SUPPLEMENT: Olive oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: ED90 of Norepinephrine and Phenylephrine Boluses Under Intensive Treatment in Preeclamptic Patients
Status: NOT_YET_RECRUITING
Conditions: Adverse Effect
Interventions: DRUG: Norepinephrine|DRUG: Phenylephrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Pulmonary Arterial Denervation in Patients With Pulmonary Hypertension Associated With the Left Heart Failure
Status: COMPLETED
Conditions: Pulmonary Hypertension
Interventions: PROCEDURE: Pulmonary arterial denervation|DRUG: Standard treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study To Measure The Effect Of Use Of Artificial Intelligence (AI) Enabled Computer Aided Detection (CADe) Assistance Software In Detecting Colon Polyps During Standard Colonoscopy Procedures
Status: TERMINATED
Conditions: Colon Polyp|Colon Neoplasm|Colon Adenoma
Interventions: DEVICE: EndoVigilant Software
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effect of Cigarette Smoke on Sleep Quality and Physical Activity in People With Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: BEHAVIORAL: Sleep quality and physical activity|GENETIC: Nicotine dependence|DIAGNOSTIC_TEST: Nicotine and cotinine serum levels|BEHAVIORAL: Smoking
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Trial of Simvastatin for the Treatment of Severe Asthma
Status: WITHDRAWN
Conditions: Severe Asthma
Interventions: DRUG: Simvastatin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Application of Targeted Reinnervation for People With Transradial Amputation
Status: UNKNOWN
Conditions: Amputation; Traumatic, Hand, and Wrist|Amputation; Traumatic, Hand, at Wrist Level
Interventions: DEVICE: Compare control of multifunction transradial prosthesis|PROCEDURE: Perform TMR surgery and evaluate transradial TMR pattern recognition control of multifunctional prostheses.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study With Docetaxel, Carboplatin and Herceptin Versus Vinorelbine and Herceptin in HER-2 (+) Metastatic Breast Cancer Patients
Status: TERMINATED
Conditions: Breast Cancer
Interventions: DRUG: Docetaxel|DRUG: Carboplatin|DRUG: Herceptin|DRUG: Vinorelbine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Whey Protein Intake With and Without Exercise on Visceral Fat: The P+RISE Study
Status: COMPLETED
Conditions: Obesity|Overweight
Interventions: DIETARY_SUPPLEMENT: Whey Protein|DIETARY_SUPPLEMENT: Whey Protein and Resistance Exericse|OTHER: Whey Protein and RISE exercise routine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Therapeutic Drug Monitoring of Brodalumab in Psoriasis Patients (BIOLOPTIM-BRO)
Status: RECRUITING
Conditions: Psoriasis Vulgaris
Interventions: PROCEDURE: Venapuncture|OTHER: Patient questionnaires
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Special Use-results Surveillance on Long Term Use of Sogroya® in Children With Short Stature Due to Growth Hormone Deficiency Where Epiphysial Discs Are Not Closed
Status: ENROLLING_BY_INVITATION
Conditions: Growth Hormone Deficiency in Children
Interventions: DRUG: Somapacitan
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Liver Transplantation in Patients With Hepatitis C Virus (HCV) and Human Immunodeficiency Virus (HIV) Coinfection
Status: TERMINATED
Conditions: HIV Infections|Hepatitis C
Interventions: PROCEDURE: liver transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PCORI-1502-27462 Navigating High Risk Surgery: Empowering Older Adults to Ask Questions That Inform Decisions About Surgical Treatment
Status: COMPLETED
Conditions: Communication
Interventions: OTHER: QPL (question prompt list) brochure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: A Study to Evaluate Efficacy and Safety of ALN-AGT01 in Patients With Mild To-Moderate Hypertension
Status: ACTIVE_NOT_RECRUITING
Conditions: Hypertension
Interventions: DRUG: Placebo|DRUG: ALN-AGT01
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Reduction Efficacy of OLOMAX for Blood Pressure and Low-density Lipoprotein Cholesterol in Hypertensive Patients With Dyslipidemia
Status: ACTIVE_NOT_RECRUITING
Conditions: Hypertension|Dyslipidemias
Interventions: DRUG: Olmesartan Medoxomil/ Amlodipine Besylate/ Rosuvastatin Ca
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of the Antioxidant Micronutrients of Rapeseed Oil on the Prevention of Cardiovascular Diseases (Optim'Oils)
Status: COMPLETED
Conditions: Cardiovascular Diseases
Interventions: DIETARY_SUPPLEMENT: Rapeseed Oil (prevention of cardiovascular diseases)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of Pyridostigmine in Postural Tachycardia Syndrome
Status: RECRUITING
Conditions: Postural Tachycardia Syndrome
Interventions: DRUG: pyridostigmine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Efficacy of Sofosbuvir, Velpatasvir, and Voxilaprevir in Subjects With Previous DAA Experience
Status: COMPLETED
Conditions: Chronic Hepatitis C
Interventions: DRUG: Sofosbuvir/Velpatasvir/Voxilaprevir
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nefopam/Paracetamol Fixed Dose Combination in Acute Pain After Impacted Third Molar Extraction
Status: COMPLETED
Conditions: Acute Pain
Interventions: COMBINATION_PRODUCT: nefopam hydrochloride 30mg / paracetamol 500mg X2|DRUG: Paracetamol 500 Mg Oral Tablet X2|DRUG: Nefopam HCl 30 MG Oral Tablet X2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Lidocaine In-situ Gel Before Intrauterine Device Insertion
Status: COMPLETED
Conditions: Pain Relief
Interventions: DRUG: lidocaine in-situ gel|DRUG: placebo in-situ gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Transposon-manipulated Allogeneic CARCIK-CD19 Cells in Pediatric and Adult Patients With r/r ALL Post HSCT
Status: COMPLETED
Conditions: Acute Lymphoblastic Leukemia, in Relapse
Interventions: BIOLOGICAL: CARCIK-CD19
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fluid Mobilization in Hospitalized Patients With Acute Kidney Injury
Status: COMPLETED
Conditions: Hypotension During Dialysis|Fluid Overload
Interventions: DRUG: (100 ml of Albumin 25%)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect OF Nitrous Oxide On Acute Pain and Opioid Consumption, and Chronic Pain After Hysterectomy
Status: WITHDRAWN
Conditions: Abdominal Hysterectomy (& Wertheim)|Nitrous Oxide|General Anesthesia
Interventions: DRUG: Nitrous oxide|OTHER: General anesthesia with oxygen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Intravenous Lidocaine Infusion During Video-assisted Thoracic Procedures for Improved Pain Control
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Lidocaine Infusion|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Pharmacokinetics Study of SyB L-1101 in Patients With Recurrent/Relapsed or Refractory Myelodysplastic Syndrome (MDS)
Status: COMPLETED
Conditions: Myelodysplastic Syndrome
Interventions: DRUG: SyB L-1101
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intravenous Levetiracetam as First-line Anticonvulsive Treatment in Patients With Non-convulsive Status Epilepticus
Status: WITHDRAWN
Conditions: Status Epilepticus, Non-Convulsive
Interventions: DRUG: first-line i/v-levetiracetam
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Device to Assist With Abdominal Access During Laparoscopic Surgery
Status: COMPLETED
Conditions: Laparoscopic Surgery
Interventions: DEVICE: TauTona Pneumoperitoneum Assist Device (TPAD)|PROCEDURE: Standard of Care (SOC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sequencing of 14 Genes From Leptin Melanocortin Pathway in Severe Obesity in Childhood.
Status: NOT_YET_RECRUITING
Conditions: Obesity, Child
Interventions: GENETIC: sequencing of a panel of 14 genes in leptin melanocortin pathway
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC