pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Evaluation of a Supporting Transition and Resilience to Clinical Nursing Education (STRONG) Study
Status: NOT_YET_RECRUITING
Conditions: Resilience|Practice Readiness|Depression|Anxiety|Stress|Physical Activity|Eating Behaviours
Interventions: BEHAVIORAL: Supporting Transition and Resilience to Clinical Nursing Education (STRONG) Program
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Bedside Therapeutic Monitoring of β-Lactam Levels in Newborns, Children and Adolescents Admitted to Intensive Care.
Status: TERMINATED
Conditions: Intensive Care Unit Syndrome
Interventions: DEVICE: pharmacokinetic device|DEVICE: pharmacokinetic device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Trial of Intravenous Denileukin Diftitox Plus Subcutaneous Pegylated IFNα-2A in Stage III or IV Ovarian Cancer
Status: TERMINATED
Conditions: Epithelial Ovarian Cancer|Extraovarian Peritoneal Cancer|Fallopian Tube Carcinoma
Interventions: DRUG: Denileukin Diftitox/SC Pegylated IFNα-2a
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects on Re-endothelialisation With Bydureon Treatment in Type 2 Diabetes Subjects
Status: COMPLETED
Conditions: Atherosclerosis|Diabetes|Restenosis
Interventions: DRUG: Bydureon|DRUG: Humulin kwickpen|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Minnesota COVID-19 Testing Project
Status: COMPLETED
Conditions: Covid19|Infectious Disease
Interventions: BEHAVIORAL: A $10 Survey Incentive|BEHAVIORAL: A $20 Survey Incentive|BEHAVIORAL: Emphasis of Government Involvement|BEHAVIORAL: Emphasis of Academic Researchers Involvement|BEHAVIORAL: Cost-Benefit Frame|BEHAVIORAL: Duty Frame|BEHAVIORAL: Racial/Ethnic Frame|BEHAVIORAL: No Messaging
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Evaluation of the Philips Respironics BiPAP autoSV Devices in Subjects With Sleep Disorders
Status: COMPLETED
Conditions: Sleep Disordered Breathing|Sleep Apnea, Central
Interventions: DEVICE: BiPAP auto Advanced|DEVICE: BiPAP auto SV4
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: PET Image in PAH Patients
Status: RECRUITING
Conditions: Pulmonary Arterial Hypertension
Interventions: DIAGNOSTIC_TEST: 18F-FGLN PET Imaging|DRUG: (18F)FPGLU
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Medium Chain Triglycerides (MCT) and Whey Protein Isolate (WPI) for Type 2 Diabetes Patients (Combine)
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DIETARY_SUPPLEMENT: BetaQuik™|DIETARY_SUPPLEMENT: WheyBasics|OTHER: Iso-voluminous water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Resistance of Helicobacter Pylori to Antibiotics in Children
Status: COMPLETED
Conditions: Abdominal Pain|Children|Bacterial Infection Due to Helicobacter Pylori (H. Pylori)|Antibiotic Resistant Strain
Interventions: OTHER: Helicobacter Pylori Culture
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Quad Shot Radiotherapy in Combination With Immune Checkpoint Inhibition
Status: SUSPENDED
Conditions: Advanced Head and Neck Squamous Cell Carcinoma|Recurrent Head and Neck Squamous Cell Carcinoma|Metastatic Head-and-neck Squamous-cell Carcinoma|Stage III Cutaneous Squamous Cell Carcinoma of the Head and Neck|Locally Advanced Head and Neck Squamous Cell Carcinoma|Stage IV Cutaneous Squamous Cell Carcinoma of the Head and Neck
Interventions: DRUG: Pembrolizumab (immunotherapy)|RADIATION: Quad-shot palliative radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Intravenous Mannitol Plus Saline on the Prevention of Cisplatin-induced Nephrotoxicity: A Randomized, Double-blind, Placebo Controlled Trial
Status: COMPLETED
Conditions: Cis-Platinum Nephropathy|Mannitol Adverse Reaction
Interventions: DRUG: Mannitol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Acupressure on Labor Pain and Anxiety Levels During Labor in Primiparas Women
Status: COMPLETED
Conditions: Labor Pain
Interventions: PROCEDURE: acupressure|PROCEDURE: sham acupressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Improving Family Quality of Life Through Training to Reduce Care-Resistant Behaviors by People With AD and TBI
Status: COMPLETED
Conditions: Dementia|Traumatic Brain Injury
Interventions: BEHAVIORAL: Caregiver Coaching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Pharmacy-based Study to Learn More About How Well Iberogast Works, How it Affects the Body, How it is Used, and User Satisfaction in Patients With Functional and Motility-related (Stomach and Bowel Movement-related) Gastrointestinal Diseases, Including Irritable Bowel Syndrome
Status: COMPLETED
Conditions: Functional and Motility Related Gastrointestinal Disorders Such as Irritable Bowel Syndrome and Functional Dyspepsia
Interventions: DRUG: Iberogast (STW5, BAY98-7411)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: DALY II USA/ MB-CART2019.1 for DLBCL
Status: RECRUITING
Conditions: Refractory Diffuse Large B Cell Lymphoma (DLBCL)|Relapsed Diffuse Large B Cell Lymphoma|High Grade B-cell Lymphoma (HGBCL)|Primary Mediastinal B-cell Lymphoma (PMBCL)|Transformed Lymphoma|Central Nervous System Lymphoma
Interventions: BIOLOGICAL: zamtocabtagene autoleucel (MB-CART2019.1)|DRUG: Cyclophosphamide|DRUG: Fludarabine|DRUG: Bendamustine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety, Tolerability, and Efficacy Study of Intracerebroventricular BMN 190 in Pediatric Patients < 18 Years of Age With CLN2 Disease
Status: COMPLETED
Conditions: Jansky-Bielschowsky Disease|Batten Disease|Late-Infantile Neuronal Ceroid Lipofuscinosis Type 2|CLN2 Disease|CLN2 Disorder
Interventions: BIOLOGICAL: BMN190 recombinant human tripeptidyl peptidase-1 (rhTPP1)|DEVICE: Intraventricular access device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Linked Color Imaging Versus High-definition White Light Endoscopy for the Detection of Polyps in Patients With Lynch Syndrome (LCI-LYNCH)
Status: COMPLETED
Conditions: Lynch Syndrome|Colonoscopy
Interventions: DIAGNOSTIC_TEST: Colonoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Perioperative Therapy for Hepatocellular Carcinoma
Status: TERMINATED
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Sintilimab Injection|DRUG: TACE|RADIATION: Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Evaluate Efficacy and Safety of Serplulimab + Chemotherapy (Carboplatin- Etoposide) in US Patients With ES-SCLC
Status: RECRUITING
Conditions: Extensive Stage Small Cell Lung Cancer
Interventions: DRUG: Serplulimab + chemotherapy (carboplatin-etoposide)|DRUG: Atezolizumab + chemotherapy (carboplatin-etoposide)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Study of Brentuximab Vedotin Given Sequentially and Combined With Multi-Agent Chemotherapy for CD30-Positive Mature T-Cell and NK-Cell Neoplasms
Status: COMPLETED
Conditions: Lymphoma, Large-Cell, Anaplastic|Lymphoma, NK-cell|Lymphoma, T-cell
Interventions: DRUG: brentuximab vedotin|DRUG: cyclophosphamide|DRUG: brentuximab vedotin|DRUG: prednisone|DRUG: cyclophosphamide|DRUG: doxorubicin|DRUG: doxorubicin|DRUG: prednisone|DRUG: vincristine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rehabilitation Following Displaced Proximal Humerus Fractures
Status: ACTIVE_NOT_RECRUITING
Conditions: Shoulder Fractures
Interventions: OTHER: Pain management and shoulder bandage|OTHER: One-time physiotherapy instruction|OTHER: Usual rehabilitation care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: "Tunnel" Flap vs Trapezoidal Flap for Lateral Sinus Lift
Status: RECRUITING
Conditions: Severe Atrophy of the Edentulous Maxilla
Interventions: PROCEDURE: Lateral Sinus Lift using tunnel flap technique|PROCEDURE: Lateral Sinus Lift using crestal incision flap
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Mometasone Furoate (SCH 032088) vs Beclomethasone Dipropionate or Placebo in Seasonal Allergic Rhinitis (C93-013)
Status: COMPLETED
Conditions: Seasonal Allergic Rhinitis
Interventions: DRUG: Mometasone Furoate (MF)|DRUG: Beclomethasone Dipropionate (BDP)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment With Continuous Sub-cutaneous Insulin Infusion Via a Portable Pump Versus Discontinuous Insulin Infusion Via Multiple-injections in Type 2 Diabetes
Status: TERMINATED
Conditions: Patient With Type 2 Diabetes Treated With Insulin Using a Baseline/Bolus Strategy
Interventions: DRUG: LEVEMIR|DRUG: APIDRA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of ACT-541468 in Healthy Japanese and Caucasian Subjects
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: ACT-541468|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Comparison of a Tissue Perfusion Guided Hemodynamic Protocol With a Standard Hemodynamic Protocol in Septic Shock Patients
Status: TERMINATED
Conditions: Septic Shock
Interventions: OTHER: Tissue perfusion guided protocol|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Binimetinib in Addition to Standard Chemotherapy in KRAS Mutated NSCLC.
Status: COMPLETED
Conditions: Advanced Non-small Cell Lung Cancer|KRAS Gene Mutation|Lung Cancer
Interventions: DRUG: Binimetinib|DRUG: Pemetrexed|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Micro and Nanoplastics in Greenhouse Workers: Biomarkers of Exposure and Effect
Status: NOT_YET_RECRUITING
Conditions: Microplastics|Nanoplastics|Genotoxic Damage|Inflammation
Interventions: OTHER: Biomonitoring of MNPLs in biological samples of greenhouse workers and controls
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Dimensional Alterations of the Edentulous Ridge Following Removal of Multiple Adjacent Teeth
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Adjacent Teeth|Bone Remodelling
Interventions: DEVICE: Implants (OsseospeedTM,EV Astra Tech System, DentsplyTM, Mölndal)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Preventing de Novo Portal Vein Thrombosis With Antithrombin-III in Patients With Cirrhosis
Status: WITHDRAWN
Conditions: Portal Vein Thrombosis|Cirrhosis, Liver
Interventions: DRUG: Antithrombin III|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Double-blind, Placebo-controlled, Crossover Study to Assess the Effect of Aclidinium Bromide 400 μg Bid on COPD Symptoms and Sleep Quality After 3 Weeks of Treatment in Patients With Stable Moderate-to-severe Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: DRUG: Aclidinium bromide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigation of Intravenous (IV) Administration of an Approved Drug (MK-0476, Montelukast Sodium) for Acute Asthma (MK-0476-288)
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: montelukast sodium|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Retaron® on Oxygen Induced Retinal Vasoconstriction in LPS Induced Inflammatory Model in Humans
Status: COMPLETED
Conditions: Imparied Retinal Vascular Reactivity|Healthy Subjects
Interventions: DRUG: Escherichia coli Endotoxin|DIETARY_SUPPLEMENT: Retaron®|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety Profile Evaluation of TICagrelor Alone Compared to a Combination of Lysine Acetylsalicylate-Clopidogrel in the Context of Transcatheter Aortic Valve Implantation (TAVI)
Status: COMPLETED
Conditions: Aortic Valve Stenosis
Interventions: DRUG: Ticagrelor alone|DRUG: Combination lysine acetylsalicylate - clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Normothermic Intraperitoneal Chemotherapy - Long Term in Peritoneal Metastases From Colorectal Cancer (NIPEC-OXA)
Status: UNKNOWN
Conditions: Peritoneal Metastases|Colo-rectal Cancer
Interventions: DRUG: Oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CBL0137 in Treating Patients With Advanced Extremity Melanoma or Sarcoma
Status: TERMINATED
Conditions: Advanced Cutaneous Melanoma of the Extremity|Advanced Sarcoma of the Extremity|Clinical Stage III Cutaneous Melanoma AJCC v8|Clinical Stage IV Cutaneous Melanoma AJCC v8|Pathologic Stage IIIB Cutaneous Melanoma AJCC v8|Pathologic Stage IIIC Cutaneous Melanoma AJCC v8|Pathologic Stage IV Cutaneous Melanoma AJCC v8|Recurrent Cutaneous Melanoma of the Extremity|Recurrent Sarcoma of the Extremity|Stage III Soft Tissue Sarcoma of the Trunk and Extremities AJCC v8|Stage IIIA Soft Tissue Sarcoma of the Trunk and Extremities AJCC v8|Stage IIIB Soft Tissue Sarcoma of the Trunk and Extremities AJCC v8|Stage IV Soft Tissue Sarcoma of the Trunk and Extremities AJCC v8
Interventions: DRUG: FACT Complex-targeting Curaxin CBL0137
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hearing Aid Signal Processing Comparative Study
Status: COMPLETED
Conditions: Hearing Loss, Sensorineural
Interventions: DEVICE: Receiver-in-canal hearing instrument; Manufacturer A|DEVICE: Receiver-in-canal hearing instrument; Manufacturer B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study of Genomic Sequencing Guided Individualized Therapy in Gastrointestinal Cancers, GITIC Study
Status: UNKNOWN
Conditions: Gastrointestinal Cancers
Interventions: DRUG: Erlotinib or Gefitinib|DRUG: Everolimus|DRUG: Imatinib|DRUG: Sorafenib or Sunitinib|DRUG: Vandetanib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Conventional Lateral Internal Sphincterotomy, V-Y Anoplasty and Tailored Lateral Internal Sphincterotomy With V-YF in Treatment of Chronic Anal Fissure(CAF)
Status: COMPLETED
Conditions: Chronic Anal Fissure
Interventions: PROCEDURE: Group I: Conventional Lateral internal sphincterotomy:|PROCEDURE: GroupII: V-Y advancement flap|PROCEDURE: GroupIII: Tailored LIS with V-Y advancement flap
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Evaluate the Safety, Immunogenicity and Efficacy of Investigational Flu Vaccine Compared to Approved Flu Vaccine in Children.
Status: COMPLETED
Conditions: Influenza Virus
Interventions: BIOLOGICAL: Adjuvanted Quadrivalent Subunit Influenza Virus Vaccine (aQIV)|BIOLOGICAL: Non-adjuvanted Trivalent Influenza Vaccine (TIV) / Quadrivalent Influenza Vaccine (QIV)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Investigate the Efficacy and Safety of BRII-835 (VIR-2218) and PEG-IFNα Combination Therapy in Chronic HBV Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Hepatitis B Virus Infection
Interventions: BIOLOGICAL: PEG-IFNα|DRUG: BRII-835
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multicenter, Open-label, Phase 1b Study of Carfilzomib, Cyclophosphamide and Dexamethasone in Newly Diagnosed Multiple Myeloma Subjects
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Carfilzomib|DRUG: Cyclophosphamide|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tailored Approach to Sleep Health Education: A Community Engaged Approach
Status: COMPLETED
Conditions: Healthcare Disparities|Minority Health|Sleep|Sleep Disorders
Interventions: BEHAVIORAL: Tailored sleep health education materials.|BEHAVIORAL: Generic sleep health education materials.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety & Efficacy of Intranasal Dexmedetomidine, Fentanyl & Midazolam in the Pediatric Emergency Room
Status: UNKNOWN
Conditions: Acute Stress Disorder|Anxiety|Pain
Interventions: DRUG: Intranasal Dexmedetomidine (4 mcg/kg)|DRUG: Intranasal Fentanyl (2 mcg/kg)|DRUG: Intranasal Midazolam (5 mg/kg)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I/II Clinical Trial of Vorinostat in Combination With Erlotinib for Patients With Relapsed/Refractory Non-Small-Cell Lung Cancer (0683-025)
Status: TERMINATED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: Vorinostat|DRUG: Vorinostat|DRUG: Vorinostat|DRUG: Vorinostat|DRUG: erlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sublingual Tablets With Cannabinoid Combinations for the Treatment of Dysmenorrhea
Status: UNKNOWN
Conditions: Dysmenorrhea|Headache, Migraine|Fatigue|Nausea|Mood Disturbance
Interventions: DRUG: Pure Femme Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficiency of Umbilical Cord-derived Mesenchymal Stem Cells(UC-MSC) in Patients With Alzheimer's Disease
Status: UNKNOWN
Conditions: Alzheimer's Disease
Interventions: BIOLOGICAL: Human Umbilical Cord Derived MSC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immune Mechanisms of Vitamin D to Reduce Chronic Pain After Burn
Status: RECRUITING
Conditions: Burn Injury|Chronic Pain
Interventions: DRUG: Ergocalciferol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Dose-Escalation Study Evaluating the Safety and Pharmacokinetics of Artesunate in Patients With Hepatocellular Carcinoma
Status: TERMINATED
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Artesunate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Dose-Ranging Study in Subjects With Mild to Moderate Ulcerative Colitis Treated With SPD476
Status: COMPLETED
Conditions: Colitis, Ulcerative
Interventions: DRUG: SPD476 is a polymeric matrix formulation that displays both delayed- and extended-release of mesalazine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lipid Peroxidation and Options Antioxidant Therapy for Secondary Lymphedema of the Lower Extremities
Status: COMPLETED
Conditions: Lower Extremity Lymphedema
Interventions: DRUG: Micronised purified flavonoid fraction (diosmin+flavonoids expressed as hesperidin)|DRUG: Tocopherol|OTHER: Elastic compression
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 3 Study to Evaluate the Immunogenicity and Safety of Inactived Split Influenza Vaccine in Healthy Korea Infants
Status: NOT_YET_RECRUITING
Conditions: Healthy
Interventions: BIOLOGICAL: IL-YANG FLU Vaccine Prefilled Syringe INJ.|BIOLOGICAL: Fluarix Tetra Pre-filled Syringe
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Rollover Extension Clinical Trial To Evaluate The Long-Term Safety And Efficacy Of KT-301 (Formerly US-APR2020) In Subjects With CKD IV Completing The US-APR2020-01 Study
Status: RECRUITING
Conditions: Chronic Kidney Disease stage4
Interventions: DRUG: KT-301 (formerly US-APR2020)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Test the Safety and Efficacy of Erlotinib Plus Bevacizumab to Treat Advanced Thymoma and Thymic Cancer
Status: COMPLETED
Conditions: Thymic Cancer|Thymoma
Interventions: DRUG: bevacizumab|DRUG: Erlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Nile Tilapia Fish Skin as a Xenograft for Burn Treatment: Phase III Study
Status: COMPLETED
Conditions: Burns
Interventions: DEVICE: Nile Tilapia Fish Skin|DRUG: Silver Sulfadiazine Cream 1%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Thermocool SF Catheter Versus Thermocool Catheter in Isthmus-dependent Atrial Flutter Ablation
Status: COMPLETED
Conditions: Atrial Flutter
Interventions: DEVICE: Atrial flutter irrigated catheter|DEVICE: Atrial flutter porous tip catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: EVALUATION OF AN ALTERNATIVE TECHNIQUE FOR THE APPLICATION OF SODIUM FLUOROPHOSPHATE: A 2-YEARS DOUBLE-BLIND RCT
Status: COMPLETED
Conditions: Caries,Dental
Interventions: COMBINATION_PRODUCT: Fluoride
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Effectiveness of Combining Ursodeoxycholic Acid With Vitamin D in Treating Patients With Primary Biliary Cholangitis
Status: COMPLETED
Conditions: Primary Biliary Cholangitis
Interventions: DRUG: Vitamin D
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity of Adacel® and BOOSTRIX® Vaccines in Adolescents
Status: COMPLETED
Conditions: Tetanus|Diphtheria|Pertussis|Whooping Cough
Interventions: BIOLOGICAL: Tetanus Toxoid, Reduced Diphtheria Toxoid and Acellular Pertussis Vaccine Adsorbed (Adacel®)|BIOLOGICAL: Tetanus Toxoid, Reduced Diphtheria Toxoid and Acellular Pertussis Vaccine, Adsorbed (BOOSTRIX®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Pyrotinib in Combination With Fulvestrant in Patients With HER2 Positive，HR-Positive Metastatic Breast Cancer
Status: UNKNOWN
Conditions: Metastatic Breast Cancer
Interventions: DRUG: Pyrotinib combined with fulvestrant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Metabolic and Microbial Profiling of Lung Cancer
Status: TERMINATED
Conditions: Nonsmall Cell Lung Cancer|Nonsmall Cell Lung Cancer Stage
Interventions: OTHER: Breath Collection|OTHER: Saliva Collection|OTHER: Blood Collection|OTHER: Urine Collection|OTHER: Tumor Collection|OTHER: Medical History Data Collection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Radifocus (Terumo) Versus Silverway (Asahi) to Deliver Catheters During Cardiac Catheterization
Status: COMPLETED
Conditions: Anomalies Vascular
Interventions: DEVICE: Silverway guidewire|DEVICE: Radifocus guidewire
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Investigate Apatinib Combined Capecitabine on Adjuvant Therapy of Biliary Carcinoma
Status: UNKNOWN
Conditions: Biliary Carcinoma
Interventions: DRUG: Capecitabine|DRUG: Apatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Global Utilization And Registry Database for Improved preservAtion of doNor LUNGs
Status: ENROLLING_BY_INVITATION
Conditions: Interstitial Lung Disease|COPD|Cystic Fibrosis|Pulmonary Fibrosis|Pulmonary Arterial Hypertension|Emphysema
Interventions: DEVICE: LungGuard|DEVICE: BAROGuard
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Using Lignocaine Spray and Gel to Reduce the Pain Associated With Nasogastric Tube Insertion in Children
Status: TERMINATED
Conditions: Intubation; Difficult
Interventions: DRUG: Lignocaine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Melatonin for Sleep in MS
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DIETARY_SUPPLEMENT: Melatonin|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pembro + Blina Combination in Pediatric and Young Adult Patients With Relapsed/Refractory Acute Leukemia or Lymphoma
Status: WITHDRAWN
Conditions: Leukemia, B-cell|Lymphoma, B-Cell
Interventions: DRUG: Blinatumomab|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 1b Dose Escalation Trial of PSK®/Placebo With Docetaxel to Treat Metastatic Castration-resistant Prostate Cancer
Status: WITHDRAWN
Conditions: Prostatic Neoplasms
Interventions: DRUG: Docetaxel, PSK®|DRUG: Docetaxel, Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Olanzapine Pamoate Depot Versus Oral Olanzapine on Treatment Outcomes in Outpatients With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: olanzapine|DRUG: olanzapine pamoate depot
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Off Label Use of Glycopyrrolate in the Adults Intensive Care Unit.
Status: UNKNOWN
Conditions: Effect of Drugs
Interventions: DRUG: Glycopyrrolate 0.2 MG|DRUG: normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prophylactic Salpingectomy With Delayed Oophorectomy
Status: ACTIVE_NOT_RECRUITING
Conditions: Ovarian Carcinoma
Interventions: OTHER: Ovarian Cancer Screening|PROCEDURE: Prophylactic Salpingectomy with Delayed Oophorectomy|PROCEDURE: Risk-Reducing Salpingo-Oophorectomy|BEHAVIORAL: Questionnaire|PROCEDURE: Transvaginal Ultrasound|BEHAVIORAL: Phone Call
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effects of Pulsed Dye and CO2 Laser in Treatment of Hypertrophic Burn Scars.
Status: COMPLETED
Conditions: Hypertrophic Scar
Interventions: PROCEDURE: Treatment with Pulse Dye Laser|PROCEDURE: Treatment with CO2 Laser|PROCEDURE: Treatment with combination of pulse dye laser and CO2 laser.|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Waking Hypnosis in the Treatment of MS-related Fatigue
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: BEHAVIORAL: Active-Alert Hypnosis|BEHAVIORAL: Traditional Hypnosis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Iodixanol Versus Iopamidol in Patients Undergoing Contrast-Enhanced Computed Tomographic Imaging of Abdomen/Pelvis
Status: COMPLETED
Conditions: Patient Comfort and Safety
Interventions: DRUG: Iodixanol|DRUG: Iopamidol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Ketorolac Versus Triamcinolone Knee Injections for Osteoarthritis
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: DRUG: Ketorolac Tromethamine|DRUG: Triamcinolone Acetonide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial to Learn How BAY1834845 and BAY1830839 Affect Inflammation When Taken by Mouth Twice a Day for 7 Days in a Row in Healthy Male Participants
Status: COMPLETED
Conditions: Immune Mediated Inflammatory Diseases
Interventions: DRUG: BAY1834845|DRUG: BAY1830839|DRUG: Prednisolone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Measurement of Cerebral Oxygenation Using NIRS Method in the Preterm Infants With Intracranial Haemorrhagia
Status: UNKNOWN
Conditions: Cerebral Oxygenation, Intracranial Haemorrhagia
Interventions: DEVICE: device:INVOS 5100
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase 2 Study With CC-220 in Skin Sarcoidosis
Status: WITHDRAWN
Conditions: Sarcoidosis
Interventions: DRUG: CC-220 0.3 mg Daily|DRUG: CC-220 0.6mg Daily|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Macrohemodynamic Impact of Fluid Removal With Net Ultrafiltration in Patients With Continuous Renal Replacement Therapy
Status: NOT_YET_RECRUITING
Conditions: Fluid Removal|Critically Ill|Continuous Renal Replacement Therapy|Fluid Overload
Interventions: OTHER: Macrohemodynamic parameters
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Morphological and Biomechanical Analysis of Knee Four Dimensional CT (4DCT) in Femoropatellar Instability
Status: UNKNOWN
Conditions: 4DCT, Knee, Femoropatellar Instability
Interventions: DIAGNOSTIC_TEST: Knee 4DCT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Tolerability and Steady-state Pharmacokinetics of BIA 6-512
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: DRUG: BIA 6-512|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Intrauterine Adhesions and Its Distribution of Genital Tract Flora
Status: UNKNOWN
Conditions: Intrauterine Adhesions
Interventions: DRUG: Intrauterine lavage therapy|DRUG: Intrauterine gel-injection therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Naproxcinod in Subjects With Osteoarthritis of the Hip
Status: COMPLETED
Conditions: Osteoarthritis|Osteoarthritis, Hip
Interventions: DRUG: Naproxcinod|DRUG: Naproxen|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Single-dose Crossover Study to Investigate Pharmacodynamics of AZD3199
Status: COMPLETED
Conditions: Asthma|Airway Obstruction
Interventions: DRUG: AZD3199|DRUG: Formoterol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of NVL-520 in Patients With Advanced NSCLC and Other Solid Tumors Harboring ROS1 Rearrangement (ARROS-1)
Status: RECRUITING
Conditions: Locally Advanced Solid Tumor|Metastatic Solid Tumor
Interventions: DRUG: NVL-520
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Study of the Efficacy of Either Krytantek Ofteno PF® or Eliptic Ofteno PF® Plus Gaap Ofteno PF® for POAG or Ocular Hypertension.
Status: TERMINATED
Conditions: Glaucoma, Open-Angle|Ocular Hypertension
Interventions: DRUG: Dorzolamide-timolol-brimonidine and latanoprost|DRUG: Dorzolamide-timolol and latanoprost
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Thymoglobulin Induction and Reduced Doses of Calcineurin Inhibitors on Liver Transplant Rejection
Status: COMPLETED
Conditions: Liver Dysfunction|Rejection, Transplant|Transplantation, Liver
Interventions: BIOLOGICAL: Thymoglobulin|DRUG: Corticosteroid|DRUG: Tacrolimus|DRUG: Mycophenolate Mofetil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to Compare SB11 (Proposed Ranibizumab Biosimilar) to Lucentis in Subjects With Neovascular Age-related Macular Degeneration (AMD)
Status: COMPLETED
Conditions: Age-Related Macular Degeneration
Interventions: DRUG: SB11 (Proposed ranibizumab biosimilar)|DRUG: Lucentis (ranibizumab)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Platelet Rich Pasma on Strenal Healing Post Median Strenotomy in Patients Undergoing Open Heart Surgery
Status: UNKNOWN
Conditions: Cardiac Surgical Procedures
Interventions: DRUG: platlet rich plasma on sternal healing post median sternotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Feasibility Study of SBRT Plus Chemotherapy for Non-Small Cell Lung Carcinoma
Status: TERMINATED
Conditions: Stage I Non-Small Cell Lung Cancer|Stage II Non-Small Cell Lung Cancer
Interventions: RADIATION: Stereotactic Body Radiotherapy|DRUG: Carboplatin|DRUG: Paclitaxel Albumin-Stabilized Nanoparticle Formulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Statin Therapy to Reduce Progression in Women With Platinum Sensitive Ovarian Cancer
Status: RECRUITING
Conditions: Recurrent Ovarian Cancer|Platinum-sensitive Ovarian Cancer
Interventions: DRUG: Simvastatin 40mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Two-Part Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of E2006 in Healthy Japanese and White Subjects
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: E2006 2.5 mg|DRUG: E2006 10 mg|DRUG: E2006 25 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Vaccine Therapy Before Surgery in Treating Patients With Localized Kidney Cancer
Status: TERMINATED
Conditions: Recurrent Renal Cell Carcinoma|Stage I Renal Cell Cancer|Stage II Renal Cell Cancer
Interventions: OTHER: Laboratory Biomarker Analysis|PROCEDURE: Nephrectomy|BIOLOGICAL: Renal Cell Carcinoma/CD40L RNA-Transfected Autologous Dendritic Cell Vaccine AGS-003
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Serplulimab in Combination With Chemotherapy in Locally Advanced Gastric or Gastro-esophageal Junction Cancer
Status: RECRUITING
Conditions: Gastric Adenocarcinoma
Interventions: DRUG: Serplulimab+SOX
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Pill Project - Oral Contraceptive and Serotonergic Brain Signaling
Status: RECRUITING
Conditions: Major Depressive Disorder|Sexual Behavior|Mood Disturbance|Mood Change|Affect Altered|Affect Blunted|Drug Mechanism
Interventions: DRUG: Femicept|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Dose-finding of Semaglutide Administered Subcutaneously Once Daily Versus Placebo and Liraglutide in Subjects With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: semaglutide|DRUG: liraglutide|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Proof of Concept Study of NBMI Treatment of Mercury Intoxication
Status: COMPLETED
Conditions: Mercury Poisoning
Interventions: DRUG: Emeramide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Evaluation of the Impact of a Single Dose of P-552 on Oral Mucosal Wetness
Status: COMPLETED
Conditions: Xerostomia|Sjogren's Syndrome
Interventions: DRUG: P-552|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Nigella Sativa in Children With House Dust Mite-Induced Respiratory Allergy Receiving Immunotherapy
Status: UNKNOWN
Conditions: House Dust Mite Allergy
Interventions: DRUG: Nigella Sativa Oil|DRUG: Allergen Specific Immunotherapy|DRUG: Standard pharmacotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intranasal Cooling for Symptomatic Relief of Migraine
Status: TERMINATED
Conditions: Migraine Headache
Interventions: DEVICE: Active RhinoChill|DEVICE: Placebo RhinoChill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Perioperative Thoracotomy Analgesia; Different Analgesic Modalities
Status: COMPLETED
Conditions: Analgesia
Interventions: PROCEDURE: serratus anterior block|PROCEDURE: thoracic epidural|PROCEDURE: erector spinae block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Accelerated Mandibular Molar Protraction: Piezocision at the Time of Molar Protraction or Later?
Status: COMPLETED
Conditions: Orthodontic Appliance
Interventions: OTHER: Piezocision
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of CBT-I in Alcoholics & Its Effects on Remission & Relapse
Status: COMPLETED
Conditions: Insomnia
Interventions: BEHAVIORAL: Cognitive Behavioral Therapy for Insomnia (CBT-I)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Integrative Ayurveda Healing Relieves Minor Sports Injury Pain
Status: COMPLETED
Conditions: Acute Pain|Sports Injury
Interventions: DEVICE: Ayurveda|DEVICE: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Incidence of Malignant Peripheral Nerve Sheath Tumor (MPNST) Development in Participants With Neurofibromatosis Type 1 (NF1) Receiving and Not Receiving Medical Therapies Directed at Plexiform Neurofibromas (PN)
Status: COMPLETED
Conditions: Neurofibromatosis 1|Peripheral Nerve Neoplasms, Malignant
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Erector Spinae Block for Thoracic Surgery
Status: RECRUITING
Conditions: Pulmonary Neoplasm|Pulmonary Cancer|Thoracic Diseases|Thoracic Cancer|Thoracic Neoplasms
Interventions: DRUG: ESB Thoracic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tantrum Tamers 2.0: The Role of Emotion
Status: COMPLETED
Conditions: Child Behavior|Attention Deficit and Disruptive Behavior Disorders|Problem Behavior
Interventions: BEHAVIORAL: Helping the Noncompliant Child (HNC)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: VItamin D in pregnanCy for prevenTion Of eaRlY Childhood Asthma
Status: NOT_YET_RECRUITING
Conditions: Asthma|Respiratory Tract Infections|Gastrointestinal Infection|Croup|Eczema|Allergy|Wheezing|Fractures, Bone|Development, Child|Cognition Disorders in Children|Psychiatric Diagnosis
Interventions: DIETARY_SUPPLEMENT: Cholecalciferol D3|OTHER: Olive oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: AMT-PET in Monitoring Telotristat Etiprate Treatment in Participants With MetastaticNeuroendocrine Neoplasm
Status: RECRUITING
Conditions: Carcinoid Syndrome|Metastatic Nonfunctional Well Differentiated Neuroendocrine Neoplasm
Interventions: OTHER: Carbon C 11 Alpha-methyltryptophan|OTHER: Laboratory Biomarker Analysis|PROCEDURE: Positron Emission Tomography|DRUG: Telotristat Etiprate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 3 Trial in Subjects With Metastatic Melanoma Comparing 3 mg/kg Ipilimumab Versus 10 mg/kg Ipilimumab
Status: COMPLETED
Conditions: Melanoma
Interventions: BIOLOGICAL: Ipilimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Evaluation of the GSK-580299 Vaccine in Women From the Control Group in the Primary NCT00294047 Study
Status: COMPLETED
Conditions: Infections, Papillomavirus
Interventions: BIOLOGICAL: GSK580299 (Cervarix)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Algeron (Cepeginterferon Alfa-2b) Compared With PegIntron (Peginterferon Alfa-2b) for Treatment of Chronic Hepatitis C
Status: COMPLETED
Conditions: Hepatitis|Hepatitis C
Interventions: DRUG: Algeron|DRUG: PegIntron|DRUG: Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Decitabine in Treating Patients With Advanced Refractory Solid Tumors or Lymphomas
Status: TERMINATED
Conditions: Hematopoietic/Lymphoid Cancer|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: decitabine|OTHER: pharmacological study|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clofarabine in Chinese Pediatric Patients With Refractory or Relapsed Acute Lymphoblastic Leukemia
Status: COMPLETED
Conditions: Acute Lymphoblastic Leukemia
Interventions: DRUG: Clofarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT