pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Facilitation of Corneal Re-epithelialization After Photorefractive Keratectomy
Status: UNKNOWN
Conditions: Corneal Erosion
Interventions: DEVICE: Cacicol20|DEVICE: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective Study Evaluating Dry Eye in Patients Operated on for Ametropia by LASIK Surgery and Treated With REPADROP
Status: COMPLETED
Conditions: Ametropia
Interventions: OTHER: Describe the evolution of dry eye between 1 month and 3 months post-LASIK
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of The Premature Infant Oral Motorınterventıon on Suckıng Capacıty in Preterm Infants
Status: COMPLETED
Conditions: Feeding Behavior|Premature Birth|Sucking Behavior
Interventions: PROCEDURE: Premature Infant Oral Motor Intervention (PIOMI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Home-based Computer Gaming in Vestibular Rehabilitation
Status: COMPLETED
Conditions: Peripheral Vestibular Disorders|Vestibular Syndromes &/or Disorders (Labyrinthine)|Vestibular Neuronitis
Interventions: BEHAVIORAL: home-based computer gaming
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Paclitaxel Albumin-Stabilized Nanoparticle Formulation and Gemcitabine in Treating Patients With Advanced Metastatic Solid Tumors
Status: COMPLETED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: gemcitabine hydrochloride|DRUG: paclitaxel albumin-stabilized nanoparticle formulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Doxycycline in Acute Traumatic Brain Injury
Status: COMPLETED
Conditions: Traumatic Brain Injury
Interventions: DRUG: Doxycycline 100 MG Oral Tablet|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Homologous Re-infection With Dengue 1 or Dengue 3
Status: ACTIVE_NOT_RECRUITING
Conditions: Dengue
Interventions: BIOLOGICAL: Dengue virus 1 Live Virus Human Challenge (DENV-1-LVHC)|BIOLOGICAL: Dengue virus 3 Live Virus Human Challenge (DENV-3-LVHC)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Fusion UltraSound Imaging Of the Thyroid GlaNd With I-124 PET. Evaluation of Nodule Allocation.
Status: UNKNOWN
Conditions: Thyroid Nodule|Thyroid Diseases|Thyroid Goitre
Interventions: OTHER: Assessment of already preacquired I-124 PET/US
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: CSF Leak Following Microvascular Decompression: the Benefit of Routine Postoperative Lumbar Tap
Status: WITHDRAWN
Conditions: Cranial Nerve Diseases|Facial Neuralgia|Trigeminal Neuralgia|Hemifacial Spasm
Interventions: PROCEDURE: prophylactic spinal tap|PROCEDURE: no prophylactic spinal tap
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluate the Safety and Efficacy of Tafasitamab and Lenalidomide in Combination With Gemcitabine and Oxaliplatin Versus Rituximab in Combination With Gemcitabine and Oxaliplatin in Patients With Relapsed/Refractory Diffuse Large B-Cell Lymphoma
Status: RECRUITING
Conditions: DLBCL
Interventions: DRUG: Tafasitamab|DRUG: Lenalidomide|DRUG: Gemcitabine|DRUG: Oxaliplatin|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Acceptability and Performance of Wearables for Atrial Fibrillation Screening in Older Adults
Status: RECRUITING
Conditions: Atrial Fibrillation|Paroxysmal Atrial Fibrillation
Interventions: DEVICE: Electrocardiogram monitoring|DEVICE: Electrocardiogram recording|DEVICE: Photoplethysmogram monitoring|OTHER: Feedback questionnaire
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Intracranial Pressure and Optic Nerve Sheath Diameter With CLOSED Bundle
Status: NOT_YET_RECRUITING
Conditions: Intra Cerebral Hemorrhage|Subarachnoid Hemorrhage, Aneurysmal|Trauma, Brain|Hypertension Intracranial|Stroke, Ischemic
Interventions: DIAGNOSTIC_TEST: ultrasound optic nerve sheath diameter assessment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Topical Dexamethasone and Tacrolimus for the Treatment of Oral Chronic Graft-Versus-Host Disease
Status: COMPLETED
Conditions: Oral Chronic Graft-versus-host Disease
Interventions: DRUG: Tacrolimus|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Outcomes of Chronic Lymphocytic Leukemia (CCL) and Mantle Cell Lymphoma (MCL) Participants Treated With Ibrutinib: A Medical Chart Review From India
Status: COMPLETED
Conditions: Leukemia, Lymphocytic, Chronic, B-Cell|Lymphoma, Mantle-Cell
Interventions: DRUG: Ibrutinib
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Adding Antiplatelet During Edoxaban Treatment in Stroke Patients With Non-valvular Atrial Fibrillation (ADD-ON)
Status: UNKNOWN
Conditions: Acute Ischemic Stroke|Atrial Fibrillation|Extracranial Atherosclerosis|Intracranial Atherosclerosis|Coronary Artery Atherosclerosis|Peripheral Artery Stenosis|Anticoagulant|Antiplatelet
Interventions: DRUG: Edoxaban Monotherapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Radiation Therapy and Durvalumab With or Without Tremelimumab in Treating Participants With Unresectable, Locally Advanced, or Metastatic Bladder Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Bladder Urothelial Carcinoma|Stage IV Bladder Cancer AJCC v8|Stage IVA Bladder Cancer AJCC v8|Stage IVB Bladder Cancer AJCC v8
Interventions: BIOLOGICAL: Durvalumab|RADIATION: External Beam Radiation Therapy|BIOLOGICAL: Tremelimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pain Management During a Photodynamic Therapy Session on the Vertex for Actinic Keratosis: Tumescent Anesthesia Interest
Status: UNKNOWN
Conditions: Pain|Actinic Keratosis|Analgesia|Phototerapy|Vertex
Interventions: DRUG: Procedure (Tumesent anesthesia)|DRUG: Control Arm (Paracetamol)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of LCL161 in Combination With Weekly Paclitaxel in Adult Patients With Advanced Solid Tumors
Status: COMPLETED
Conditions: Solid Tumors
Interventions: DRUG: LCL161|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Different Pain Rating Scales in Patients With Symptomatic Teeth
Status: COMPLETED
Conditions: Pain|Dental Pain
Interventions: DIAGNOSTIC_TEST: numerical rating scale|OTHER: visual analogue scale|OTHER: color analogue scale|OTHER: faces rating scale
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: MRI and Neurodevelopment in Preterm Infants Following Administration of High-Dose Caffeine
Status: COMPLETED
Conditions: Apnea of Prematurity|Intraventricular Hemorrhage|Brain Injury
Interventions: DRUG: Caffeine citrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Onset Time of Rocuronium in Emergency and Elective Surgery
Status: UNKNOWN
Conditions: Inguinal Hernia|Acute Appendicitis
Interventions: DRUG: Rocuronium elective surgery|DRUG: Rocuronium emergency surgery|DRUG: Propofol|DRUG: Fentanyl|OTHER: Ringer Lactate|DEVICE: Acceleromyography device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Li-Hep vs. Non-Li-Hep Coated Transfer Device
Status: COMPLETED
Conditions: Acute Coronary Syndrome|Chest Pain|Myocardial Infarction|Cardiac Ischemia
Interventions: DEVICE: Siemens® Point-of-care high sensitive troponin I analyzer
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical Study of Cord Blood-derived CAR NK Cells Targeting CD19/CD70 in Refractory/Relapsed B-cell Non-Hodgkin Lymphoma
Status: RECRUITING
Conditions: B-cell Non Hodgkin Lymphoma
Interventions: BIOLOGICAL: CB dualCAR-NK19/70
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Somatic Yoga and Meditation for Cancer Survivors With Pain From Neuropathy
Status: COMPLETED
Conditions: Cancer Survivor|Pain|Chemotherapy Induced Peripheral Neuropathy|Function|Fall Risk|Balance|Quality of Life
Interventions: BEHAVIORAL: Somatic Yoga and Meditation (SYM)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparision of the Use in Marcaine and Chloroprocaine in Rachianesthesia for the Surgical Correction of Inguinal Hernia.
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Chloroprocaine|DRUG: Marcaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Magnetic Resonance Imaging in High Risk Patients for the Development of Diffuse Idiopathic Skeletal Hyperostosis (DISH)
Status: UNKNOWN
Conditions: Hyperostosis, Diffuse Idiopathic Skeletal|Metabolic Syndrome|Diabetes Mellitus
Interventions: DIAGNOSTIC_TEST: Thoracic spine x-rays+whole spine MRI|DIAGNOSTIC_TEST: blood tests|OTHER: constitutional and demographic data collection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Chicken Egg Antibody (IgY) on Patients With Chronic Gastritis
Status: COMPLETED
Conditions: Chronic Gastritis Caused by Helicobacter Pylori
Interventions: DIETARY_SUPPLEMENT: GastimunHP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oxaliplatin and Paclitaxel Plus Bevacizumab in Advanced Peritoneal Carcinomatosis
Status: COMPLETED
Conditions: Peritoneal Cancer
Interventions: DRUG: Bevacizumab|DRUG: Oxaliplatin|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Propranolol for Challenging Behaviors in Autism
Status: ACTIVE_NOT_RECRUITING
Conditions: Autism Spectrum Disorder|Developmental Disability|Aggression|Self-Injurious Behavior|Challenging Behavior
Interventions: DRUG: Propranolol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Parkinson's Disease: Enhancing Physical Therapy With Brain Stimulation for Treating Postural Instability.
Status: RECRUITING
Conditions: Parkinson Disease
Interventions: DEVICE: Active Comparator: Active tDCS and Active TUS|DEVICE: Sham Comparator: Sham TDCS and Sham TUS|OTHER: Physical Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Dose-finding Study of GSK2248761 in Antiretroviral Therapy-Naive Subjects (SIGNET)
Status: TERMINATED
Conditions: Infection, Human Immunodeficiency Virus
Interventions: DRUG: GSK2248761 100 mg once daily|DRUG: GSK2248761 200 mg once daily|DRUG: Efavirenz 600 mg once daily
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: iCanCope With Pain: A Smartphone and Web Self-management Program for Adolescents and Young Adults With Chronic Pain
Status: COMPLETED
Conditions: Chronic Pain
Interventions: BEHAVIORAL: iCanCope app and website|BEHAVIORAL: Attention control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Phase I Dose Finding Study for Melatonin in Pediatric Oncology Patients With Relapsed Solid Tumors
Status: COMPLETED
Conditions: Relapsed Malignant Solid Tumor
Interventions: DRUG: Melatonin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: CWT Versus AT on Selected Cardiovascular Indices and Functional Capacity in Patients With Ischemic Cardiomyopathy.
Status: NOT_YET_RECRUITING
Conditions: Ischemic Cardiomyopathy
Interventions: DIAGNOSTIC_TEST: Circuit weight versus aerobic training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The HOME Study (HPN With OMEGA-3)
Status: COMPLETED
Conditions: Patients Requiring Home Parenteral Nutrition
Interventions: DRUG: Lipidem|DRUG: Lipofundin MCT 20%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of a Exercise Program on Health Outcomes in People With Diabetic Foot Ulcers
Status: COMPLETED
Conditions: Diabetic Foot Ulcer|Diabetes Mellitus, Type 2
Interventions: OTHER: EnhanceFitness community exercise program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Botulinum Toxin Type A Associated With Physical Therapy on Children With Spastic Cerebral Palsy
Status: COMPLETED
Conditions: Cerebral Palsy, Spastic|Physical Therapy|Botulinum Toxin
Interventions: DRUG: Botulinum toxin type A|OTHER: Physical Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treadmill Training With and Without Weighted Ankle Cuffs on Gait Parameters
Status: COMPLETED
Conditions: Down's Syndrome
Interventions: OTHER: Treadmill training with weighted ankle cuffs|OTHER: Treadmill training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Online Positive Emotion Skills Intervention for Symptoms of Depression
Status: COMPLETED
Conditions: Depression|Psychological Stress|Affect
Interventions: BEHAVIORAL: Positive Affect Skills Training|BEHAVIORAL: 5-week Emotion Reporting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Functional Endoscopic Sinus Surgery Study
Status: RECRUITING
Conditions: Chronic Rhinosinusitis (Diagnosis)
Interventions: DRUG: Bupivacaine or Ropivacaine with epinephrine plus dexamethasone - Group 1|DRUG: Bupivacaine or Ropivacaine with epinephrine plus dexamethasone - Group 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: TACE Plus Tegafur Versus TACE for Intrahepatic Cholangiocarcinoma After Curative Resection
Status: UNKNOWN
Conditions: Intrahepatic Cholangiocarcinoma
Interventions: PROCEDURE: TACE+Tegafur|PROCEDURE: TACE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intraoral Injection of Trigger Points by Botox
Status: ENROLLING_BY_INVITATION
Conditions: Myofacial Pain
Interventions: DRUG: intraoral trigger point injection by botox|DRUG: transcutaneous trigger point injection by botox
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Memory and Cognitive Performance Study
Status: COMPLETED
Conditions: Cognitive Function|Memory|Brain Health
Interventions: DIETARY_SUPPLEMENT: Braini|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Low-dose Computed Tomography-guided Core Needle Biopsy for Lung Nodules
Status: COMPLETED
Conditions: Lung Cancer|Lung; Node
Interventions: DIAGNOSTIC_TEST: Low-dose computed tomography|DIAGNOSTIC_TEST: Standard-dose computed tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: TXA Study in Major Oncologic Surgery
Status: COMPLETED
Conditions: Tranexamic Acid|Cancer|Major Surgery
Interventions: DRUG: Tranexamic Acid|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Erector Spinae Plane Block Catheters and Intrathecal Morphine for Hepatic Resection
Status: RECRUITING
Conditions: Hepatic Resection|Acute Pain|Anesthesia|Anesthesia, Local
Interventions: DRUG: 0.2% ropivacaine local anesthetic continuous erector spinae plane block|DRUG: 0.2% ropivacaine local anesthetic superficially taped continuous erector spinae plane block|DRUG: Spinal Morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial for Relapsed Multiple Myeloma Patients (Isatuximab-dexamethasone)
Status: ACTIVE_NOT_RECRUITING
Conditions: Relapsed Multiple Myeloma
Interventions: DRUG: Isatuximab-dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Safety, Pharmacokinetics, Pharmacodynamics of JNJ-61610588 in Participants With Advanced Cancer
Status: TERMINATED
Conditions: Advanced Cancer
Interventions: DRUG: JNJ-61610588
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of the Angiotensin II Receptor Antagonist Micardis® (Telmisartan) or Hydrochlorothiazide in the Management of Patients With Isolated Systolic Hypertension (ISH)
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Low dose of Micardis®|DRUG: Medium dose of Micardis®|DRUG: High dose of Micardis®|DRUG: Hydrochlorothiazide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Pilot E2 for Hypogonadal Women With CFBD
Status: WITHDRAWN
Conditions: Cystic Fibrosis Related Bone Disease
Interventions: DRUG: Estradiol 2 mg|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Correlation of FC Gamma RIIIA Receptor Response in Patients With Waldenstrom's Macroglobulinemia
Status: COMPLETED
Conditions: Waldenstrom's Macroglobulinemia
Interventions: DRUG: Rituximab|DRUG: monoclonal antibodies
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose:
Clinical trial: A Study of Two Different Schedules of Xeloda (Capecitabine) as First Line Therapy in Patients With Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: capecitabine|DRUG: Oxaliplatin|DRUG: bevacizumab|DRUG: capecitabine|DRUG: Oxaliplatin|DRUG: bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Autologous Adipose Tissue Derived Mesenchymal Stem Cells Transplantation in Patient With Avascular Necrosis of the Femoral Head
Status: COMPLETED
Conditions: Avascular Necrosis of the Femoral Head
Interventions: PROCEDURE: Autologous Adipose Tissue derived MSCs Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Eccentric Manual Resistance Training in Patients With Ischemic CMP
Status: COMPLETED
Conditions: Ischemic Cardiomyopathy
Interventions: OTHER: Eccentric manual resistance training|OTHER: Concentric manual resistance resistance training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Time-restricted Eating and Cognition
Status: RECRUITING
Conditions: Time Restricted Eating|Intermittent Fasting
Interventions: BEHAVIORAL: Early Time-Restricted Eating|BEHAVIORAL: Late Time-Restricted Eating
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Study on the Effectiveness and Safety of Electroacupuncture at ST36 in Treating Primary Premature Ejaculation
Status: RECRUITING
Conditions: Premature Ejaculation
Interventions: DEVICE: Electroacupuncture at ST36
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Belimumab With Rituximab for Primary Membranous Nephropathy
Status: ACTIVE_NOT_RECRUITING
Conditions: Membranous Nephropathy|Nephrotic Syndrome
Interventions: DRUG: Belimumab|DRUG: Placebo for Belimumab|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Mindfulness and Intercare Based Intervention for Medicine Students (MIIM)
Status: COMPLETED
Conditions: Depressive Symptoms|Mental Health Wellness 1|Anxiety
Interventions: BEHAVIORAL: Mindfulness, compassion and intercare based Intervention|BEHAVIORAL: Psychoeducational based intervention|OTHER: General curricular intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Follicular Flushing Outcomes in Singles Versus Double Lumen Oocyte Retrieval Needles in Poor Responding Patients
Status: COMPLETED
Conditions: Infertility
Interventions: PROCEDURE: single lumen needle in oocyte retrieval|PROCEDURE: double lumen needle in oocyte retrieval
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Phase I/II Study to Assess the Safety and Efficacy of Vaccinations With Allogeneic Dendritic Cells: Autologous Tumor-Derived Cells Subjected to Electrofusions in Patients With AJCC Stage IV Renal Cell Carcinoma
Status: COMPLETED
Conditions: Renal Cell Carcinoma
Interventions: BIOLOGICAL: Electrofusion DC vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Metabolic Cost of Walking With Passive vs. Powered Microprocessor Controlled Knees
Status: COMPLETED
Conditions: Amputation|Prosthesis User
Interventions: DEVICE: Power Knee Mainstream Dynamic|DEVICE: Passive microprocessor controlled knee
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Autologous Platelet Rich Plasma (PRP) for the Treatment of Chronic Non-Healing Ulcers
Status: COMPLETED
Conditions: Chronic Ulcer
Interventions: BIOLOGICAL: Autologous PRP Gel and PRP Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: PACT for Individuals With Serious Mental Illness
Status: COMPLETED
Conditions: Schizophrenia Spectrum & Other Psychotic Disorders
Interventions: OTHER: Patient Aligned Care Team (PACT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Preoperative Image-based Education Effect on Postoperative Satisfaction of Patients Undergoing First-time Dermatologic Surgery
Status: WITHDRAWN
Conditions: Skin Cancer|Skin Wound
Interventions: OTHER: Preoperative image-based education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Randomized, Double-Blind Study of 566C80 Versus Septra (Sulfamethoxazole/Trimethoprim) for the Treatment of Pneumocystis Carinii Pneumonia in AIDS Patients
Status: COMPLETED
Conditions: Pneumonia, Pneumocystis Carinii|HIV Infections
Interventions: DRUG: Atovaquone|DRUG: Sulfamethoxazole-Trimethoprim
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: Bryostatin 1 Plus Vincristine in Treating Patients With Recurrent or Refractory HIV-Related Lymphoma
Status: COMPLETED
Conditions: AIDS-related Diffuse Large Cell Lymphoma|AIDS-related Diffuse Mixed Cell Lymphoma|AIDS-related Peripheral/Systemic Lymphoma|AIDS-related Small Noncleaved Cell Lymphoma
Interventions: DRUG: bryostatin 1|DRUG: vincristine sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gene Therapy for Beta-Thalassemia Major Using Autologous Hematopoietic Stem Cell Genetically Modified
Status: UNKNOWN
Conditions: Beta Thalassemia Major
Interventions: GENETIC: Autologous CD34+ cells genetically modified
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Albuterol HFA MDI in Pediatric Participants With Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Albuterol|DRUG: Placebo|DRUG: Proventil® HFA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Kukoamine B Mesilate in Sepsis Patients
Status: RECRUITING
Conditions: Sepsis
Interventions: DRUG: 16mg，KB|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Zoledronic Acid as Adjuvant Therapy in Neovascular Age-related Macular Degeneration (Z-AMD)
Status: COMPLETED
Conditions: Neovascular Age-related Macular Degeneration
Interventions: DRUG: Zoledronic Acid 5 MG in 5 ML Injection|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Radiant Warmer Trial
Status: WITHDRAWN
Conditions: Body Temperature Changes
Interventions: DEVICE: GEHC IWS 4400 & Giraffe Warmer beds|DEVICE: GEHC IWS 4400 & Giraffe Warmer beds|DEVICE: GEHC IWS 4400 & Giraffe Warmer beds|DEVICE: GEHC IWS 4400 & Giraffe Warmer beds|DEVICE: GEHC IWS 4400 & Giraffe warmer beds|DEVICE: GEHC IWS 4400 & Giraffe Warmer beds
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Metastatic Rhabdomyosarcoma or Sarcoma
Status: COMPLETED
Conditions: Sarcoma
Interventions: BIOLOGICAL: dactinomycin|BIOLOGICAL: filgrastim|BIOLOGICAL: pegfilgrastim|BIOLOGICAL: sargramostim|DRUG: cyclophosphamide|DRUG: irinotecan hydrochloride|DRUG: vincristine sulfate|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Efficiency of Inferior Alveolar Nerve Block and Buccal Infiltration Techniques Using Articaine 4% 1:100000
Status: UNKNOWN
Conditions: Anesthesia, Local
Interventions: DRUG: inferior alveolar nerve block with 4% articaine|DRUG: buccal infiltration with 4% articaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Trial of High-Dose Ascorbate in Glioblastoma Multiforme
Status: ACTIVE_NOT_RECRUITING
Conditions: Glioblastoma Multiforme
Interventions: DRUG: Temozolomide|RADIATION: radiation therapy|DRUG: Ascorbic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Green Tea, High in Epigallocatechin Gallate (EGCG) and Postprandial Fat Oxidation
Status: COMPLETED
Conditions: Obesity|Type 2 Diabetes Mellitus
Interventions: DIETARY_SUPPLEMENT: Effect of the green tea extract TEAVIGO, high in EGCG, on postprandial fat oxidation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Clomiphene Citrate in Combination With Gonadotropins for Ovarian Stimulation in Women With Poor Ovarian Response.
Status: UNKNOWN
Conditions: Female Infertility
Interventions: DRUG: Clomiphene citrate|DRUG: Gonadotropins
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: All-Trans Retinoic Acid in Combination With Standard Induction and Consolidation Therapy in Older Patients With Newly Diagnosed Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Cytarabine|DRUG: Idarubicin|DRUG: All-trans retinoic acid|DRUG: Mitoxantrone|DRUG: Etoposid
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Pharmacokinetic (PK) Study of Ibuprofen and Diphenhydramine Hydrochloride MR Tablets in Healthy Adults Under Fasting Condition
Status: NOT_YET_RECRUITING
Conditions: Pain|Insomnia
Interventions: DRUG: Compound ibuprofen polyrelease tablets|DRUG: reference 1 (R1): Ibuprofen Tablets (Motrin IB®)reference 2 (R2): Diphenhydramine Hydrochloride Tablets (Benadryl®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Motivational Interviewing Technique on Loneliness Levels in University Students Aged 18-25 Living Far From Home
Status: COMPLETED
Conditions: Loneliness
Interventions: BEHAVIORAL: motivational interview technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy and Safety of Dexketoprofen/Vitamin B vs Dexketoprofen for Post-traumatic Cervical Sprain Grade I-II
Status: COMPLETED
Conditions: Acute Low Back Pain
Interventions: DRUG: Dexketoprofen/Vitamin B|DRUG: Dexketoprofen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trials to Validate the Use of Additioned Endoscopy in Endoscopic Retrograde Cholangiopancreatography
Status: UNKNOWN
Conditions: ERCP
Interventions: DEVICE: Additioned Endoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Palbociclib In Combination With Letrozole As Treatment Of Post-Menopausal Women With HR+, HER2- Advanced Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Palbociclib|DRUG: Letrozole
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Human Placental-Derived Stem Cell Transplantation
Status: COMPLETED
Conditions: Mucopolysaccharidosis I|Mucopolysaccharidosis VI|Adrenoleukodystrophy|Niemann-Pick Disease|Metachromatic Leukodystrophy|Wolman Disease|Krabbe's Disease|Gaucher's Disease|Fucosidosis|Batten Disease|Severe Aplastic Anemia|Diamond-Blackfan Anemia|Amegakaryocytic Thrombocytopenia|Myelodysplastic Syndrome|Acute Myelogenous Leukemia|Acute Lymphocytic Leukemia
Interventions: DRUG: Human Placental Derived Stem Cell
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Pazopanib in Combination With Weekly Paclitaxel in Refractory Urothelial Cancer
Status: COMPLETED
Conditions: Bladder Cancer|Bladder (Urothelial, Transitional Cell) Cancer|Bladder (Urothelial, Transitional Cell) Cancer Superficial (Non-Invasive)|Bladder (Urothelial, Transitional Cell) Cancer Resectable (Pre-Cystectomy)|Bladder (Urothelial, Transitional Cell) Cancer Metastatic or Unresectable
Interventions: DRUG: Pazopanib (GW786034)|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Sertraline Alone and Interpersonal Psychotherapy Alone in Treating Women With Postpartum Depression
Status: COMPLETED
Conditions: Depression, Postpartum
Interventions: DRUG: Sertraline|DRUG: Placebo|BEHAVIORAL: Interpersonal psychotherapy (IPT)|BEHAVIORAL: Clinical management|BEHAVIORAL: Mothercrafting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clomiphene Citrate for the Treatment of Obesity Related Male Hypogonadism
Status: COMPLETED
Conditions: Obesity|Hypoandrogenism
Interventions: DRUG: Clomiphene Citrate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Effect of Food on the Bioavailability of the IGF-1R Inhibitor AXL1717 in Patients With Advanced Malignant Tumors
Status: COMPLETED
Conditions: Solid Tumors|Hematological Malignancies
Interventions: DRUG: Fasted treatment: AXL1717|DRUG: Fed treatment: AXL1717
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Lansoprazole for Subgroups of Functional Dyspepsia
Status: TERMINATED
Conditions: Functional Dyspepsia
Interventions: DRUG: Lansoprazole|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dexmedetomine as Adjuvant for Spinal Anesthesia in Elective Cesarian Sections : a Pilot Study
Status: COMPLETED
Conditions: Analgesia|Analgesics, Opioid|Anesthesia, Obstetrical|Anesthesia, Spinal|Analgesics, Non-Narcotic|Dexmedetomidine|Analgesia, Obstetrical
Interventions: DRUG: Dexmedetomidine 0.004 MG/ML [Precedex]|DRUG: Opioids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Adipose Stem/Stromal Cells in RSD, CRPS, Fibromyalgia
Status: WITHDRAWN
Conditions: RSD (Reflex Sympathetic Dystrophy)|CRPS - Complex Regional Pain Syndrome Type I|Fibromyalgia
Interventions: PROCEDURE: Lipoaspiration|PROCEDURE: ADcSVF isolation|PROCEDURE: Normal Saline IV
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: eLIFEwithIBD - Living With Intention, Fullness and Engagement With Inflammatory Bowel Disease (Online)
Status: COMPLETED
Conditions: Inflammatory Bowel Diseases
Interventions: BEHAVIORAL: eLIFEwithIBD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Effectiveness of BENLYSTA (Belimumab) in Systemic Lupus Erythematosus (SLE) Registry
Status: ACTIVE_NOT_RECRUITING
Conditions: Systemic Lupus Erythematosus
Interventions: BIOLOGICAL: BENLYSTA|OTHER: SLE treatment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Radiolabeled Monoclonal Antibody With or Without Peripheral Stem Cell Transplantation in Treating Children With Recurrent or Refractory Lymphoma
Status: TERMINATED
Conditions: AIDS-related Peripheral/Systemic Lymphoma|AIDS-related Primary CNS Lymphoma|Post-transplant Lymphoproliferative Disorder|Recurrent Childhood Large Cell Lymphoma|Recurrent Childhood Lymphoblastic Lymphoma|Recurrent Childhood Small Noncleaved Cell Lymphoma|Recurrent/Refractory Childhood Hodgkin Lymphoma
Interventions: BIOLOGICAL: rituximab|RADIATION: indium In 111 ibritumomab tiuxetan|RADIATION: yttrium Y 90 ibritumomab tiuxetan|PROCEDURE: peripheral blood stem cell transplantation|BIOLOGICAL: filgrastim|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Peginterferon Alfa-2a to Enhance Anti-leukemic Responses After Allogeneic Transplantation in Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: peg-IFN-α|PROCEDURE: Hematopoietic Cell Transplant (HCT)|DRUG: Tacrolimus|DRUG: Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Study Evaluating the Safety, Pharmacokinetics and Pharmacodynamics of PRTX-100 in Healthy Adult Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: BIOLOGICAL: PRTX-100 (Staphylococcal protein A)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of Postoperative Carbon Ion Radiotherapy for Thymus Tumor With Residual Tumor
Status: RECRUITING
Conditions: Thymic Epithelial Tumor|Radiotherapy Side Effect|Carbon Ion Radiotheray|Heavy Ion Radiotherapy
Interventions: RADIATION: Carbon ion radiotherapy|OTHER: combined with platinum-based regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effeciency of NMN in Improving IVF/ICSI-ET Pregnancy Outcomes in Patients With DOR
Status: RECRUITING
Conditions: Diminished Ovarian Reserve
Interventions: DIETARY_SUPPLEMENT: NMN|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Safety of Glycopyrronium/Formoterol Fumarate Fixed-dose Combination Relative to Umeclidinium/Vilanterol Fixed-dose Combination Over 24 Weeks in Patients With Moderate to Very Severe Chronic Obstructive Pulmonary Disease
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease COPD
Interventions: DRUG: Glycopyrronium/Formoterol Fumarate|DRUG: umeclidinium/vilanterol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Inspiratory Muscle Training and Respiratory Electromyographic Activity in COPD
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: OTHER: Inspiratory Muscle Training|OTHER: Pulmonary Rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: GOOD-DAY Trial in Paediatric Obesity
Status: COMPLETED
Conditions: Obesity, Childhood
Interventions: BEHAVIORAL: Mediterranean-Style Diet Educational Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I Safety and Immunogenicity Trial of Live Recombinant Canarypox ALVAC-HIV (vCP205) in HIV-1 Uninfected Adult Volunteers
Status: COMPLETED
Conditions: HIV Infections
Interventions: BIOLOGICAL: ALVAC-HIV MN120TMG (vCP205)|BIOLOGICAL: ALVAC-RG Rabies Glycoprotein (vCP65)|BIOLOGICAL: rgp120/HIV-1 SF-2
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Comparison of Analgesic Efficacy and Occurrence of Emesis Among Different Background Infusion and Bolus Administration Regimens of Fentanyl Based Intravenous Patient-controlled Analgesia in Patients After Laparoscopic Assisted Gastrectomy - a Randomized Blind Study -
Status: UNKNOWN
Conditions: The Patients With Gastric Cancer Who Are Scheduled to Receive Laparoscopy Assisted Gastrectomy
Interventions: DRUG: B0 group: bolus 0.6mcg/kg without background infusion|DRUG: BL group: bolus 0.4mcg/kg with background infusion rate 0.2mcg/kg/hr|DRUG: BH group: bolus 0.2mcg/kg with background infusion rate 0.4mcg/kg/hr
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Long-Term Safety, Tolerability and Efficacy Study of Darifenacin in Adult Patients With Overactive Bladder
Status: COMPLETED
Conditions: Overactive Bladder Syndrome
Interventions: DRUG: Darifenacin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial to Compare Pharmacokinetics of Two Different PEG-rhGH Preparations
Status: NOT_YET_RECRUITING
Conditions: Pediatric Growth Hormone Deficiency (PGHD)
Interventions: DRUG: PEG-rhGH with new preparation|DRUG: PEG-rhGH with present preparation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Reduced Intensity Conditioning (RIC) Regimen for Patients With Non-malignant Disorders
Status: ACTIVE_NOT_RECRUITING
Conditions: Non Malignant Diseases|Immunodeficiencies|Hemoglobinopathies
Interventions: DRUG: RIC: Distal Campath|DRUG: RIC:Intermediate Campath|DRUG: RIC: Mini Busulfan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Dose-Finding Study Comparing InSite Vision, Inc. 101 to Vehicle and DuraSite Alone for Dry Eye Disease
Status: WITHDRAWN
Conditions: Dry Eye Disease
Interventions: DRUG: ISV 101
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: DEB-TACE Plus Lenvatinib or Sorafenib or PD-1 Inhibitor for Unresectable Hepatocellular Carcinoma
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: DEB-TACE plus Sorafenib|DRUG: DEB-TACE plus Lenvatinib|DRUG: DEB-TACE plus PD-1 inhibitor
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Blind Fascia Iliaca Compartment Block Compared to Ultrasound-guided Femoral Nerve Block in Patients With Hip Fractures
Status: UNKNOWN
Conditions: Hip Fractures
Interventions: PROCEDURE: Fascia Iliaca Compartment Block|PROCEDURE: Femoral Nerve Block|DRUG: Ropivacaine
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Concurrent or Sequential Immunotherapy and Radiation Therapy in Patients With Metastatic Lung Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Stage IV Small Cell Lung Cancer
Interventions: DRUG: Nivolumab|DRUG: Ipilimumab|RADIATION: Stereotactic body radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Enoxaparin Versus Unfractionated Heparin in PCI
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DRUG: Enoxaparin i.v.|DRUG: unfractionated heparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Virtual Reality Experience for Stress Reduction in Cardiology Patients
Status: COMPLETED
Conditions: Stress|Blood Pressure|Virtual Reality|Prevention
Interventions: DEVICE: 30-minute Virtual Reality (VR) Experience delivered through Oculus Quest 2 VR headset
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Secondary Prevention of Problems in Health Status in Patients With Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease|Health Status
Interventions: BEHAVIORAL: Intervention pulmonary nurse
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Black Pepper on the Absorption of Nutrients in Vegetables
Status: COMPLETED
Conditions: Black Pepper|Absorption|Carotenoid
Interventions: OTHER: salad dressing (canola oil) and black pepper|OTHER: salad dressing (canola oil)|OTHER: black pepper|OTHER: salad|OTHER: Salad dressing (olive oil) and black pepper|OTHER: Salad dressing (corn oil) and black pepper|OTHER: Salad dressing (sunflower oil) and black pepper|OTHER: Salad dressing (flaxseed oil) and black pepper
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Efficacy of ABT-450/Ritonavir/ABT-267; (ABT-267 Also Known as Ombitasvir) and ABT-333 (Also Known as Dasabuvir) Coadministered With Ribavirin (RBV) in Hepatitis C Virus (HCV) Genotype 1-infected Adults With Compensated Cirrhosis
Status: COMPLETED
Conditions: Chronic Hepatitis C Infection|Compensated Cirrhosis
Interventions: DRUG: ABT-450/r/ABT-267, ABT-333|DRUG: Ribavirin (RBV)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT