pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Pharmacokinetic and Mass Balance Study of Oral-Administrated [14C]-DZD9008 in Healthy Male Subjects
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: [14C]-DZD9008
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Esophageal Mucosal Changes in Achalasia Cardia and Reversibility After Per Oral Endoscopic Myotomy - A Pilot Study
Status: COMPLETED
Conditions: Histopathology
Interventions: PROCEDURE: PER ORAL ENDOSCOPY MYOTOMY (POEM)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Mealworm Protein Ingestion on Muscle Protein Synthesis After Running Exercise in Humans
Status: COMPLETED
Conditions: Muscle Protein Synthesis
Interventions: DIETARY_SUPPLEMENT: Insect protein|BEHAVIORAL: Running exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SVV and PPV Predict Fluid Responsiveness in Mechanically Ventilated Elderly Patients Under General Anesthesia
Status: UNKNOWN
Conditions: Stroke Volume Variation|Pulse Pressure Variation|Fluid Responsiveness|Fluid Therapy
Interventions: DIAGNOSTIC_TEST: volume expansion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Motor Imagery Exercise and Tongue Strength
Status: UNKNOWN
Conditions: Dysphagia
Interventions: BEHAVIORAL: Active Jaw Exercise with Relaxation|BEHAVIORAL: Active Tongue Exercise|BEHAVIORAL: Active Tongue Exercise + Mental Practice|BEHAVIORAL: Mental Practice Tongue Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multi-Arm Study to Test the Efficacy of Immunotherapeutic Agents in Multiple Sarcoma Subtypes
Status: COMPLETED
Conditions: Advanced and/or Metastatic Sarcoma
Interventions: DRUG: Durvalumab|DRUG: Tremelimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evidence-based Internet Cognitive-behavioral Therapy for Social Anxiety
Status: NOT_YET_RECRUITING
Conditions: Social Anxiety
Interventions: BEHAVIORAL: Self-referred, undirected Internet-based cognitive behavioral therapy for social anxiety|BEHAVIORAL: Recommended, undirected Internet-based cognitive behavioral therapy for social anxiety|BEHAVIORAL: Recommended, directed Internet-based cognitive behavioral therapy for social anxiety
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fulvestrant Plus Anlotinib in HR(+)/HER2(-) Metastatic Breast Cancer With FGFR Mutation
Status: RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Fulvestrant plus Anlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Zinc Acetate Lozenges on the Rate of Recovery From the Common Cold
Status: COMPLETED
Conditions: Common Cold|Respiratory Tract Infections
Interventions: DEVICE: Lozenges|DEVICE: Placebo lozenges
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Assessing Safety and Efficacy of B-cure Laser Treating Diabetic Chronic Wounds
Status: UNKNOWN
Conditions: Diabetic Foot Ulcer
Interventions: DEVICE: standard hoem treatment|DEVICE: LLLT-808 B-cure laser machine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: FET PET in Differentiating Tumour Progression From Pseudoprogression in High Grade Glioma
Status: NOT_YET_RECRUITING
Conditions: Glioma, Malignant
Interventions: DIAGNOSTIC_TEST: FET PET
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Salud y Vida 2.0: Enhancing Integrated Behavioral Health for Diabetics in the Rio Grande Valley
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Behavior, Health
Interventions: OTHER: Peer-led Support Group|OTHER: Behavioral Health Consult|OTHER: Medication Therapy Management Consult|OTHER: La Cocina Alegre/ The Happy Kitchen|OTHER: Mind, Exercise, Nutrition, Do it!
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of a New Formulation of Insulin Glargine With Lantus in Patients With Type 2 Diabetes on Basal Insulin With Oral Antidiabetic Therapy
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Lantus (Insulin glargine)|DRUG: HOE901-U300 (new formulation of insulin glargine)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bevacizumab in Treating Patients With Relapsed or Refractory Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma and Plasma Cell Neoplasm
Interventions: BIOLOGICAL: bevacizumab|GENETIC: gene expression analysis|GENETIC: protein expression analysis|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Allergen Immunotherapy for Allergic Rhinitis in Thais
Status: COMPLETED
Conditions: Rhinitis, Allergic, Perennial
Interventions: BIOLOGICAL: Intervention|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of LY3502970 in Chinese Participants With Obesity or Are Overweight With Weight-related Comorbidities
Status: COMPLETED
Conditions: Overweight|Obesity
Interventions: DRUG: LY3502970|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of Canagliflozin and Metformin Immediate Release (50 mg/500 mg) FDC Tablets in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Canagliflozin tablets|DRUG: Metformin IR tablets|DRUG: Canagliflozin/metformin IR FDC tablets|DRUG: Canagliflozin/metformin IR FDC tablets|DRUG: Canagliflozin tablets|DRUG: Metformin IR tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Dose Proportionality Study of Quinine Sulfate Capsules Under Fasting Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Quinine Sulfate Capsules 324 mg|DRUG: Quinine Sulfate Capsules 324 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Add-on Methotrexate for the Treatment of Schizophrenia
Status: UNKNOWN
Conditions: Schizophrenia
Interventions: DRUG: Methotrexate|OTHER: Placebo Arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Decitabine+Cladribine+Cytarabine+Granulocyte Colony-stimulating Factor (D-CLAG) for Relapsed or Refractory Acute Myeloid Leukemia (AML)
Status: UNKNOWN
Conditions: Acute Myeloid Leukemia
Interventions: PROCEDURE: D-CLAG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Rucaparib in Patients With Metastatic Hormone-Sensitive Prostate Cancer Harboring Germline DNA Repair Gene Mutations
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Cancer Metastatic
Interventions: DRUG: Rucaparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: S1314, Co-expression Extrapolation (COXEN) Program to Predict Chemotherapy Response in Patients With Bladder Cancer
Status: COMPLETED
Conditions: Bladder Cancer
Interventions: DRUG: Gemcitabine|DRUG: Cisplatin|DRUG: Methotrexate|DRUG: Vinblastine|DRUG: Doxorubicin|DRUG: Filgrastim
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Trial With Dendritic Cells in Patients With Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Neoplasms
Interventions: DRUG: Dendritic Cell Vaccine|OTHER: Supportive treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: DBT Compared to I/GDC for the Treatment of Opiate Addiction in Emotionally Dysregulated Patients. - 1
Status: COMPLETED
Conditions: Dialectical Behavior Therapy|Individual and Group Drug Counseling
Interventions: BEHAVIORAL: DBT|BEHAVIORAL: I/GDC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Effectiveness of Rilonacept for Treating Systemic Juvenile Idiopathic Arthritis in Children and Young Adults
Status: COMPLETED
Conditions: Juvenile Idiopathic Arthritis
Interventions: BIOLOGICAL: Rilonacept
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial To Evaluate ANT-1207 In Subjects With Crow's Feet
Status: COMPLETED
Conditions: Lateral Canthal Lines|Crow's Feet
Interventions: BIOLOGICAL: ANT-1207|BIOLOGICAL: Botulinum Toxin, Type A|BIOLOGICAL: Botulinum Toxin Type A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Examining The Effect of Blood Flow Restricted Aerobic Training on Mitochondrial Adaptations in Young Healthy Adults
Status: COMPLETED
Conditions: Mitochondrial Biogenesis
Interventions: OTHER: BFR Exercise Training|OTHER: CTL Exercise Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Intra-hepatic Chemotherapy in Patients With Liver Metastases From Breast Cancer and Limited Extrahepatic Disease
Status: COMPLETED
Conditions: Metastatic Breast Cancer|Liver Metastases
Interventions: DRUG: oxaliplatin, capecitabine, trastuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized Control Trial of Antibiotic Treatment Duration For Asymptomatic Bacteriuria After Kidney Transplantation
Status: COMPLETED
Conditions: Kidney Transplantation|Bacteriuria|Asymptomatic Infections
Interventions: DRUG: 7 days course of antibiotic treatment|DRUG: 14 days course of antibiotic treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial of a New Combination Treatment, Domvanalimab and Zimberelimab, Plus Chemotherapy, for People With an Upper Gastrointestinal Tract Cancer That Cannot be Removed With Surgery That Has Spread to Other Parts of the Body
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Upper Gastrointestinal Tract Adenocarcinoma
Interventions: DRUG: Domvanalimab|DRUG: Zimberelimab|DRUG: Capecitabine|DRUG: Fluorouracil|DRUG: Leucovorin|DRUG: Oxaliplatin|DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasound-guided Botulinum Toxin Injection on Cricopharyngeal Muscle Dysfunction
Status: RECRUITING
Conditions: Cricopharyngeal Achalasia
Interventions: DRUG: Injectable Type A Botulinum Toxin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of Wearable Intensive Nerve Stimulation on Spasticity and Function in Persons With Spinal Cord Injury
Status: COMPLETED
Conditions: Spinal Cord Injuries|Spasticity, Muscle
Interventions: OTHER: Wearable intensive nerve stimulator
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lidocaine and Triamcinolone vs Saline Trigger Point Injection for Treatment of Chronic Abdominal Wall Pain
Status: WITHDRAWN
Conditions: Chronic Abdominal Wall Pain|Abdominal Cutaneous Nerve Entrapment Syndrome
Interventions: DRUG: Triamcinolone|OTHER: Placebo|DRUG: Lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Oats Containing 1.4g Beta Glucan on Fecal Bacterial Population(s) and Plasma Cholesterol in Healthy Adults With Elevated Cholesterol Levels
Status: COMPLETED
Conditions: Microbiome|Plasma Cholesterol|Prebiotic
Interventions: OTHER: Hot Cereal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Efficacy of Adjuvant Oral Care in Prevention of Ventilator Associated Pneumonia.
Status: NOT_YET_RECRUITING
Conditions: Pneumonia, Ventilator-Associated
Interventions: PROCEDURE: Comprehensive Oral Care|PROCEDURE: Traditional Oral Care|DEVICE: Mechanical Tooth Brushing using 0.2% Chlorhexidine|DEVICE: Moisturizing Gel|DEVICE: Oral care using Cotton swab dipped in 0.2% Chlorhexidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Peginterferon and TIL Therapy for Metastatic Melanoma
Status: COMPLETED
Conditions: Metastatic Melanoma
Interventions: DRUG: Cyclophosphamide|DRUG: Fludarabine|BIOLOGICAL: TIL infusion|DRUG: Interleukin-2|DRUG: Peginterferon alfa-2b
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Expanded Access Protocol for Tabelecleucel for Patients With Epstein-Barr Virus-Associated Viremia or Malignancies
Status: NO_LONGER_AVAILABLE
Conditions: Epstein-Barr Virus (EBV) Infections|Lymphoproliferative Disorders|EBV+ Associated Lymphoma|EBV+ Associated Post-transplant Lymphoproliferative Disease (EBV+ PTLD)|Epstein-Barr Viremia|Lymphoma, AIDS-related|Epstein-Barr Virus-associated Lymphoproliferative Disease (EBV+ LPD) With Primary Immunodeficiency (PID)|Leiomyosarcoma (LMS)|Nasopharyngeal Carcinoma (NPC)|Epstein-Barr Virus-associated Lymphoproliferative Disease (EBV+ LPD) With Acquired Immunodeficiency (AID)|Solid Organ Transplant Complications|Stem Cell Transplant Complications
Interventions: BIOLOGICAL: tabelecleucel
Study Type: EXPANDED_ACCESS
Clinical trial: Preference for Clarinex Tablets vs. Zyrtec Tablets in Patients With Allergies (P03181)
Status: COMPLETED
Conditions: Seasonal Allergic Rhinitis|Perennial Allergic Rhinitis
Interventions: DRUG: Desloratadine 5 mg (Clarinex)|DRUG: Cetirizine (Zyrtec)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: BLESSED: Expanded Access for DeltaRex-G for Advanced Pancreatic Cancer, Sarcoma and Carcinoma of Breast
Status: AVAILABLE
Conditions: Pancreatic Cancer|Osteosarcoma|MPNST (Malignant Peripheral Nerve Sheath Tumor)|Chondrosarcoma|Soft Tissue Sarcoma|Chordoma|Sarcoma|Carcinoma of Breast
Interventions: DRUG: DeltaRex-G
Study Type: EXPANDED_ACCESS
Clinical trial: Auricular Acupressure (AA) For Insulin Resistance in Women With Polycystic Ovary Syndrome
Status: UNKNOWN
Conditions: Polycystic Ovary Syndrome|Insulin Resistance
Interventions: OTHER: Auricular acupoints acupressure|OTHER: Sham auricular acupoints acupressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comprehensive Cohort Study of Bracing for Adolescent Idiopathic Scoliosis (AIS): A Feasibility Study
Status: COMPLETED
Conditions: Adolescent Idiopathic Scoliosis
Interventions: DEVICE: Brace
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immunologic Response to Kansui in Treated HIV+ Individuals: a Dose Escalation Study
Status: TERMINATED
Conditions: HIV|Human Immunodeficiency Virus
Interventions: DRUG: Euphorbia kansui extract powder prepared as tea
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of an Investigational Vaccine in Pre-Adolescents and Adolescents (Gardasil)(V501-016)
Status: COMPLETED
Conditions: Cervical Cancer|Genital Warts
Interventions: BIOLOGICAL: V501, Gardasil, human papillomavirus (type 6, 11, 16, 18) recombinant vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: G-CSF in the Treatment of Toxic Epidermal Necrolysis
Status: COMPLETED
Conditions: Stevens - Johnson Syndrome
Interventions: DRUG: recombinant granulocyte - colony stimulating factor|DRUG: NaCl 0.9%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Development of an Intervention to Reduce Heavy Drinking and Improve HIV Care Engagement Among Fisherfolk in Uganda
Status: UNKNOWN
Conditions: Alcohol Use Disorder|HIV-infection/Aids
Interventions: BEHAVIORAL: Behavioral and Structural Intervention|BEHAVIORAL: Screening and Referral
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Vascular Effect of Tibolone Versus Placebo Evaluated by Flow-mediated Dilatation of Brachial Artery
Status: COMPLETED
Conditions: Flow-mediated Dilation Evaluation of the Brachial Artery
Interventions: DRUG: Tibolone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: BAFF/IL-17 Bispecific Antibody Treatment in Subjects With Primary Sjogren's Syndrome
Status: WITHDRAWN
Conditions: Primary Sjogren's Syndrome
Interventions: DRUG: tibulizumab (LY3090106)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Cognitive Behavioral Therapy of Primary Obsessions in Obsessive Compulsive Disorder
Status: COMPLETED
Conditions: Obsessive Compulsive Disorder
Interventions: BEHAVIORAL: Cognitive Behavioral Therapy|BEHAVIORAL: Stress Management Therapy (SMT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ma-Spore ALL 2020 Study
Status: RECRUITING
Conditions: B Lymphoblastic Leukemia
Interventions: DRUG: Prednisolone|DRUG: Dexamethasone|DRUG: Vincristine|DRUG: Methotrexate|DRUG: L-Asparaginase|DRUG: Pegylated asparaginase|DRUG: Erwinase|DRUG: Dasatinib|DRUG: Imatinib|DRUG: Cyclophosphamide|DRUG: Cytarabine|DRUG: Mercaptopurine|DRUG: Thioguanine|DRUG: Rituximab|DRUG: Doxorubicin|DRUG: Fludarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Toxoplasma Gondii Infection in Both Children and Adult Patients With Hematological Malignancies
Status: NOT_YET_RECRUITING
Conditions: Toxoplasmosis
Interventions: DIAGNOSTIC_TEST: toxoplasma igG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Dates as a Functional Food for Autism
Status: COMPLETED
Conditions: Autistic Spectrum Disorder
Interventions: OTHER: Dates fruit as functional Food|BEHAVIORAL: behavioral modification and stimulation|OTHER: nutritional Guidance
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Success Rate, Continence, and Quality of Life With a Bioprosthetic Plug for Treating Complex Anal Fistula
Status: COMPLETED
Conditions: Complex Anal Fistula
Interventions: PROCEDURE: Anal fistula plug
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Observational Study Investigating the Change in Blood Cholesterol With Mevalotin® Tablet Administration in Korean Menopausal Women Aged 50 Years or More Who Require Treatment of Dyslipidemia
Status: ACTIVE_NOT_RECRUITING
Conditions: Dyslipidemia
Interventions: DRUG: Mevalotin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Treating Tuberculosis With the Lipid Lowering Drug Atorvastatin in Nigeria(ATORvastatin in Pulmonary TUBerculosis)
Status: COMPLETED
Conditions: Tuberculosis, Pulmonary|Tuberculosis
Interventions: DRUG: Atorvastatin with standard anti tuberculosis drugs|DRUG: Standard anti tuberculosis drugs only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Acupuncture on IVF Pregnancy Outcomes for Women With RIF
Status: RECRUITING
Conditions: Repeated Implantation Failure
Interventions: DEVICE: acupuncture and IVF|DEVICE: sham acupuncture and IVF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Impact of Reformulated Foods on Cardiovascular Risk Factors
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus|Cardiovascular Disease|Obesity
Interventions: DIETARY_SUPPLEMENT: Reformulated products|DIETARY_SUPPLEMENT: Conventional products
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Ticagrelor Monotherapy After 3 Months in the Patients Treated With New Generation Sirolimus Stent for Acute Coronary Syndrome (TICO Study)
Status: UNKNOWN
Conditions: Acute Coronary Syndrome
Interventions: DRUG: Ticagrelor monotherapy|DRUG: Ticagrelor with Aspirin DAPT(dual antiplatelet treatment)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Effects of TENS and CTM on Primary Dysmenorrhea
Status: COMPLETED
Conditions: Primary Dysmenorrhea
Interventions: OTHER: Connective Tissue Manipulation|OTHER: Transcutaneous Electrical Nerve Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testing an Intervention to Foster Hope for Cancer Survivors With Lymphedema
Status: UNKNOWN
Conditions: Mastectomy Related Lymphedema|Lymphedema of Upper Limb|Lymphedema of Lower Extremity
Interventions: BEHAVIORAL: Intervention Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: An Efficacy, Safety, Tolerability and Pharmacokinetics Study of 12 Weeks Treatment With Simeprevir and Daclatasvir in Participants With Chronic Hepatitis C Virus Genotype 1b or 4 Infection and Either Severe Renal Impairment or End-stage Renal Disease on Hemodialysis.
Status: WITHDRAWN
Conditions: Renal Impairment|End-stage Renal Disease
Interventions: DRUG: Simeprevir (SMV) 150 mg|DRUG: Daclatasvir (DCV) 60 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Safety and Pharmacokinetics of ABT-414 for Subjects With Glioblastoma Multiforme
Status: COMPLETED
Conditions: Glioblastoma Multiforme
Interventions: DRUG: ABT-414|DRUG: Temozolomide|RADIATION: Whole Brain Radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: rTMS in Treatment Refractory Obsessive-Compulsive Disorder
Status: WITHDRAWN
Conditions: Obsessive-Compulsive Disorder
Interventions: DEVICE: rTMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Genetically-informed Therapy for ER+ Breast Cancer Post-CDK4/6 Inhibitor
Status: RECRUITING
Conditions: Advanced Breast Cancer
Interventions: DRUG: Fulvestrant|DRUG: Neratinib|DRUG: Alpelisib|DRUG: Everolimus|DRUG: Abemaciclib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Administration of Vitamin C in Patients With Sepsis or Septic Shock in Emergency Departments
Status: COMPLETED
Conditions: Sepsis|Septic Shock|Sepsis, Severe
Interventions: DRUG: Vitamin C|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Massage With Senna-based Laxatives Versus Senna-based Laxatives in Managing Overflow Retentive Stool Incontinence
Status: COMPLETED
Conditions: Massage
Interventions: OTHER: Abdominal massage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Inferior Vena Cava Compliance in Trans-thoracic Echocardiography: is the Trans-hepatic Window as Reliable as the Subcostal One
Status: COMPLETED
Conditions: Surgical Procedure, Unspecified
Interventions: DEVICE: Transthoracic echocardiogram|DEVICE: Clear Sight system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Epidural Fentanyl-bupivacaine Versus Clonidine-bupivacaine for Breakthrough Pain in Advanced Labor
Status: WITHDRAWN
Conditions: Labor Pain
Interventions: DRUG: Clonidine or fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Melatonin Plus Aminoacids for Sarcopenic Elderly
Status: COMPLETED
Conditions: Sarcopenia
Interventions: DRUG: Melatonin 1mg|DIETARY_SUPPLEMENT: Essential Aminoacids (eAA)|COMBINATION_PRODUCT: Essential Aminoacids + melatonin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Three Anti-HIV Drug Combinations in Patients Who Have Taken Amprenavir
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Indinavir sulfate|DRUG: Amprenavir|DRUG: Nevirapine|DRUG: Lamivudine|DRUG: Stavudine|DRUG: Zidovudine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Evaluate The Accuracy Of Breast MRI Biopsy In Diagnosing A Complete Tumor Response For Some Women Following Neoadjuvant Chemotherapy For Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer
Interventions: PROCEDURE: MRI Biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Assessing the Surgical Skills of Trainees in Learning the LDG
Status: COMPLETED
Conditions: Gastrostomy|Surgical Procedure, Unspecified|Assessment, Self
Interventions: PROCEDURE: Laparoscopic distal gastrectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Sublingual Apomorphine in Refractory Restless Legs Syndrome
Status: UNKNOWN
Conditions: Restless Legs Syndrome
Interventions: DRUG: Apomorphine Sublingual Film|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Nonverbal Vocalisations on Pain Tolerance
Status: RECRUITING
Conditions: Healthy
Interventions: BEHAVIORAL: Cold pressor task (CPT)|BEHAVIORAL: Acoustic Recordings|DIAGNOSTIC_TEST: Index measurement NOL™|DIAGNOSTIC_TEST: Video pupillometry
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Polyphenol/Prebiotic Blend Effects on GI Health and Microbial Composition
Status: COMPLETED
Conditions: GI Health|Microbial Composition
Interventions: DIETARY_SUPPLEMENT: Polyphenol/prebiotic blend
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Simultaneously Implementing Pathways for Improving Asthma, Pneumonia, and Bronchiolitis Care for Hospitalized Children
Status: RECRUITING
Conditions: Asthma|Pneumonia|Bronchiolitis
Interventions: BEHAVIORAL: Multi-condition Pathway Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effect of Probiotics on Mycoplasma Pneumoniae Pneumonia
Status: NOT_YET_RECRUITING
Conditions: Mycoplasma Pneumoniae Pneumonia
Interventions: DIETARY_SUPPLEMENT: Probiotic|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: FM 140 vs FM100 Study in Patients With Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Melphalan|DRUG: Fludarabine|PROCEDURE: Stem Cell Infusion|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Determine Tolerable Dosis of Vorinostat in Patients With Mild Alzheimer Disease
Status: TERMINATED
Conditions: Alzheimer Disease
Interventions: DRUG: N-hydroxy-N'-phenyl-octanediamide (Vorinostat)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of the Efficacy of Two Dietary Supplements on Hair Loss and Hair Aspect
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DIETARY_SUPPLEMENT: Wheat Polar Lipid Complex Oil|DIETARY_SUPPLEMENT: Wheat Polar Lipid Complex Powder|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Trial to Determine the Efficacy of Lactobacillus Rhamnosus for Reducing Colonization by Methicillin-resistant Staphylococcus Aureus (MRSA) (PROSE)
Status: COMPLETED
Conditions: Infection
Interventions: DIETARY_SUPPLEMENT: Lactobacillus rhamnosus|DIETARY_SUPPLEMENT: Sugar pill (placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Methodology Validation: Correlating Adherent Scalp Flaking Score (ASFS) With Phototrichogram for Scalp Dandruff Evaluation in Adult Subjects
Status: COMPLETED
Conditions: Dandruff
Interventions: OTHER: Hair Wash Shampoo
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Double-Blind Study Determining the Efficacy of CannaXR in Decreasing UVA Premutagenic and Photoaging Markers
Status: COMPLETED
Conditions: Photoaging
Interventions: DEVICE: In a double-blinded fashion, 250 mg CANNAXR cream|DEVICE: Topical VEHICLE cream
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Cannabinoid Receptor (CB1) Agonist Treatment in Severe Chronic Anorexia Nervosa
Status: COMPLETED
Conditions: Anorexia Nervosa
Interventions: DRUG: dronabinol|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Early Extubation by ECCO2R Compared to IMV in Patients With Severe Acute Exacerbation of COPD
Status: RECRUITING
Conditions: COPD Exacerbation
Interventions: DEVICE: Extracorporeal carbon dioxide removal|OTHER: Conventional Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Does Body Positioning Affect the Yield of Hyperventilation in Routine Pediatric Electroencephalography - EEG Studies?
Status: UNKNOWN
Conditions: Epilepsy, Absence
Interventions: OTHER: hyperventilation while sitting up during routine EEG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy and Outcomes of Neodymium-doped Yttrium Aluminum Garnet (Nd: YAG) Laser Capsulotomy Performed by Optometrists
Status: UNKNOWN
Conditions: Posterior Capsule Opacification Obscuring Vision
Interventions: PROCEDURE: Neodymium-doped Yttrium Aluminum Garnet (Nd: YAG) Laser Capsulotomy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of the Incidence of Intraocular Inflammation and Suspected Endophthalmitis Among Patients Treated With Aflibercept, Vial and Pre-filled Syringe, 2014-2022
Status: COMPLETED
Conditions: Intraocular Inflammation|Suspected Endophthalmitis
Interventions: OTHER: Non Applicable
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase I/IIa Study of Cerebraca Wafer Plus Adjuvant Temozolomide (TMZ) in Patients With Recurrent High Grade Glioma
Status: ACTIVE_NOT_RECRUITING
Conditions: Recurrent High Grade Glioma
Interventions: DRUG: Cerebraca wafer
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Topical Probiotic Sinus Irrigations for Treating Chronic Sinusitis
Status: NOT_YET_RECRUITING
Conditions: Chronic Rhinosinusitis (Diagnosis)
Interventions: DRUG: Lactobacillus sakei proBio65|OTHER: Isotonic Saline Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Web-Based Self-Monitoring Activity-Restriction and Relaxation Training Program for Kids With Mild Traumatic Brain Injury
Status: COMPLETED
Conditions: Brain Injury Traumatic Mild
Interventions: BEHAVIORAL: Self-Monitoring Activity-restriction and Relaxation Training (SMART)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pharmacodynamics, Safety, Tolerability, and Pharmacokinetics of Two Orally Inhaled Indacaterol Salts in Adult Subjects With Asthma.
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Indacaterol maleate|DRUG: Indacaterol acetate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effective Treatments for Jellyfish Stings
Status: COMPLETED
Conditions: Jellyfish Stings
Interventions: OTHER: Acetic Acid (5%)|OTHER: Sodium Bicarbonate Slurry (50%)|OTHER: Papain Slurry (70%)|OTHER: Ammonia (10%)|DRUG: Lidocaine (4%)|OTHER: Isopropyl Alcohol (70%)|OTHER: Hot Tap Water (40 degrees Celsius)|OTHER: No treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bone Marrow Aspirate Concentrate (BMAC) Supplementation for Osteochondral Lesions
Status: COMPLETED
Conditions: Osteochondral Lesions of Talus
Interventions: PROCEDURE: ankle arthroscopy with debridement and microfracture of the OLT|OTHER: Bone Marrow Aspirate injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of High Dose Symlin to Treat Type 2 Diabetes Mellitus
Status: UNKNOWN
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Pramlintide|DRUG: Pramlintide|DRUG: Pramlintide|DRUG: Pramlintide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Drug Interaction Study Between AVP-923 and Itraconazole and Between AVP-786 and Itraconazole in Healthy Adult Subejcts
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: AVP-923|DRUG: AVP-786|DRUG: Itraconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Vinblastine and Carboplatin in Treating Young Patients With Newly Diagnosed or Recurrent Low-Grade Glioma
Status: COMPLETED
Conditions: Brain and Central Nervous System Tumors|Neurofibromatosis Type 1
Interventions: DRUG: carboplatin|DRUG: vinblastine sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Prospective, Multi-Center Evaluation of the ECHELON CIRCULAR Powered Stapler in Left-Sided Colorectal Anastomoses
Status: COMPLETED
Conditions: Left-sided Colon Resection
Interventions: DEVICE: Left-sided colon resection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dual Site-Dual Channel Non-invasive Brain Stimulation for Motor Function in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DEVICE: M1 stimulation|DEVICE: PMC stimulation|DEVICE: Sham stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of PLX51107 in Advanced Malignancies
Status: TERMINATED
Conditions: Solid Tumors|Acute Myeloid Leukemia|Myelodysplastic Syndrome|Non-Hodgkin's Lymphoma
Interventions: DRUG: PLX51107
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Dry Needling to Manual Therapy for Patients With Mechanical Low Back Pain
Status: COMPLETED
Conditions: Low Back Pain
Interventions: OTHER: Manual therapy|OTHER: Dry needling|OTHER: Home Exercise Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treating Type 2 Diabetes by Reducing Postprandial Glucose Elevations: A Paradigm Shift in Lifestyle Modification
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: BEHAVIORAL: Weight reduction training|BEHAVIORAL: PPG training|BEHAVIORAL: discrete BG feedback|BEHAVIORAL: continuous BG feedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Variability of Sulfotransferase 1A1 Activity in Humans: an Approach to Improve Predictive Drug Response - Part I: Analysis of Intraindividual Variation in Healthy Adults
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Paracetamol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Psychological and Postural Effects of Exposure to Both Types of Virtual Environments
Status: RECRUITING
Conditions: Autonomous Subjects, Aged 65 and Afraid of Falling
Interventions: DIAGNOSTIC_TEST: Rocking environment forward (B) followed by a translation environment|DIAGNOSTIC_TEST: Translation environment followed by a rocking environment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pharmacokinetics and Safety/Tolerability After Oral Administration of CKD-370 and D745 in Healthy Adults
Status: UNKNOWN
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: CKD-370|DRUG: D745
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimizing Antibiotic Dosing Regimens for the Treatment of Infection Caused by Carbapenem Resistant Enterobacteriaceae
Status: UNKNOWN
Conditions: Drug Resistance|Carbapenem-Resistant Enterobacteriaceae Infection|Sepsis|Septic Shock|Critical Illness|Clinical Outcomes|Treatment Outcomes
Interventions: OTHER: Combined antibiotic regimens|OTHER: Standard antibiotic regimens
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact on Morbidity and Mortality of Prophylactic Dosing of Low Molecular Heparin in Child-Pugh B Cirrhotic Patients
Status: SUSPENDED
Conditions: Cirrhosis
Interventions: DRUG: Enoxaparine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy With or Without Radiation Therapy in Treating Patients With Newly Diagnosed Rhabdomyosarcoma
Status: COMPLETED
Conditions: Sarcoma
Interventions: BIOLOGICAL: dactinomycin|BIOLOGICAL: filgrastim|BIOLOGICAL: sargramostim|DRUG: cyclophosphamide|DRUG: vincristine sulfate|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Etiology of Treatment Failure in HIV Positive Children and Adolescents on Boosted Protease Inhibitor-based Regimens
Status: COMPLETED
Conditions: HIV
Interventions: OTHER: modified directly administered anti-retroviral therapy (mDAART)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Sunitinib Malate in Treating Younger Patients With Recurrent, Refractory, or Progressive Malignant Glioma or Ependymoma
Status: COMPLETED
Conditions: Childhood Cerebellar Anaplastic Astrocytoma|Childhood Cerebral Anaplastic Astrocytoma|Childhood Cerebral Astrocytoma|Childhood Infratentorial Ependymoma|Childhood Mixed Glioma|Childhood Oligodendroglioma|Childhood Supratentorial Ependymoma|Recurrent Childhood Cerebellar Astrocytoma|Recurrent Childhood Cerebral Astrocytoma|Recurrent Childhood Ependymoma|Recurrent Childhood Subependymal Giant Cell Astrocytoma
Interventions: OTHER: Diagnostic Laboratory Biomarker Analysis|OTHER: Pharmacological Study|DRUG: Sunitinib Malate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Research Among 3 Action Protocol in Other to Approach Chronic Patellar Tendinopathy
Status: COMPLETED
Conditions: Tendinopathy
Interventions: OTHER: Group of Dry Needling|OTHER: Group of Electrolysis|OTHER: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Microorganisms on Reusable Tourniquets
Status: ACTIVE_NOT_RECRUITING
Conditions: Microbial Colonization|Infection, Bacterial|HAI|Nurse's Role|Vascular Access Device Complications|Vascular Access Complication|CRBSI - Catheter Related Bloodstream Infection|Catheter Infection|Device Colonisation
Interventions: DEVICE: collection of microbiological material from reusable tourniquets
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Efficiency of the Central Venous Catheter Care Protocol
Status: RECRUITING
Conditions: Stem Cell Transplant Complications|Central Venous Catheter Exit Site Infection
Interventions: PROCEDURE: CENTRAL VENOUS CATHETER CARE PROTOCOL
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: the Effect of Trans-nasal Fixation of Endotracheal Tubes for Prone Ventilation
Status: COMPLETED
Conditions: Prone Craniotomy|Endotracheal Intubation Fixation
Interventions: DEVICE: SFC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Low Voltage Electrical Stimulation for Depression in Parkinson's Patients
Status: NOT_YET_RECRUITING
Conditions: Parkinson Disease|Depressive Symptoms
Interventions: DEVICE: BIOPAC Stimsola|DEVICE: BIOPAC Stimsola Sham (zero amps)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Managing Agitated Delirium With Neuroleptics and Anti-Epileptics as a Neuroleptic Sparing Strategy
Status: ACTIVE_NOT_RECRUITING
Conditions: Delirium|Epileptics|Neuroleptics
Interventions: DRUG: Haloperidol|DRUG: Chlorpromazine|DRUG: Valproate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Online Education Module to Accurately Classify Polyp Size
Status: ACTIVE_NOT_RECRUITING
Conditions: Colorectal Polyp|Colonic Neoplasms
Interventions: OTHER: ESTIMATE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Trial to Test if Antibiotic Ointments & Cream Will Sting After Application on a Minor Wound After Tape Stripping Injury
Status: COMPLETED
Conditions: Sting
Interventions: DRUG: Saline|DRUG: Isopropyl Alcohol|DRUG: Pain Relieving Cream|DRUG: Antibiotic/Pain Relieving Ointment|DRUG: Original Ointment|DRUG: Pain Relief Ointment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT