pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: The Effect of Nocturnal Wear of Dentures on Sleep and Oral Health Related Quality of Life
Status: COMPLETED
Conditions: Sleep Apnea, Obstructive
Interventions: BEHAVIORAL: Sleeping with denture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Immunogenicity and Safety of DTPa-HBV-IPV/Hib Compared to DTPa-IPV/Hib and HBV Administered Concomitantly
Status: COMPLETED
Conditions: Hepatitis B|Diphtheria|Haemophilus Influenzae Type b (Hib)|Poliomyelitis|Pertussis|Tetanus
Interventions: BIOLOGICAL: DTPa-HBV-IPV/Hib (Infanrix-hexa™)|BIOLOGICAL: DTPa-IPV/Hib (Infanrix-IPV/Hib™)|BIOLOGICAL: HBV (Engerix™-B)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Open, Pharmacokinetic Study of Caspofungin in Neonates and Infants (0991-058)
Status: COMPLETED
Conditions: Candidiasis
Interventions: DRUG: caspofungin acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Doxycycline and Rivaroxaban in COVID-19
Status: UNKNOWN
Conditions: COVID-19
Interventions: DRUG: Doxycycline Tablets|DRUG: Rivaroxaban 15Mg Tab|COMBINATION_PRODUCT: Hydroxychloroquine and Azithromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intensive Stress Coping Intervention Week - A Secondary Prevention For Real World Affective Disorder Patients
Status: COMPLETED
Conditions: Affective Disorders|Psychological Stress|Inflammation|Oxidative Stress|Anxiety Disorders|Mood Disorders|Emotions
Interventions: BEHAVIORAL: stress-coping week|BEHAVIORAL: additional two days follow-up weekend
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Roentgen Stereophotogrammetric Analysis (RSA) Trial Comparing Trabecular Metal Monoblock and Modular Tibial Components
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DEVICE: Trabecular Metal Modular Tibial Total Knee Component|DEVICE: Trabecular Metal Monoblock Tibial Total Knee Component
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Follicular Revival in Treatment-resistant Alopecia Areata: Evaluating Use of Micro-needling
Status: COMPLETED
Conditions: Alopecia Areata
Interventions: DEVICE: Tattoo machine (SOL Nova Device)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Surgery for Gastrointestinal Metastases of Malignant Melanoma - a Single Center Retrospective Cohort Study
Status: COMPLETED
Conditions: Melanoma Stage Iv|Melanoma Metastatic|Abdominal Tumor
Interventions: PROCEDURE: Abdominal surgery with metastasectomy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Treatment of FUS-Related ALS With Betamethasone - The TRANSLATE Study
Status: COMPLETED
Conditions: Familial Amyotrophic Lateral Sclerosis
Interventions: DRUG: Betamethasone sodium phosphate/betamethasone acetate (Celestone® Soluspan®), 30 mg IM once a day for four days
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Anshen Buxin Liuwei Pills for the Treatment of Cardiac Neurosis
Status: RECRUITING
Conditions: Cardiac Neurosis
Interventions: DRUG: Anshen Buxin Liuwei Pill|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Niraparib and Selenium for the Treatment of Recurrent BRCA Negative Platinum Resistant Ovarian Cancer
Status: NOT_YET_RECRUITING
Conditions: Platinum-Resistant Fallopian Tube Carcinoma|Platinum-Resistant Ovarian Carcinoma|Platinum-Resistant Primary Peritoneal Carcinoma|Recurrent Fallopian Tube Carcinoma|Recurrent Ovarian Carcinoma|Recurrent Primary Peritoneal Carcinoma
Interventions: PROCEDURE: Biopsy|PROCEDURE: Biospecimen Collection|DRUG: Niraparib|OTHER: Questionnaire Administration|DIETARY_SUPPLEMENT: Selenium
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Sildenafil on Penile Vascular Function in Hypertensive Men With Erectile Dysfunction
Status: COMPLETED
Conditions: Arterial Hypertension|Erectile Dysfunction
Interventions: DRUG: sildenafil citrate|OTHER: comparator group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II Study of TRK-820 Soft Capsules - Intractable Pruritus in Patients With Chronic Liver Disease -
Status: COMPLETED
Conditions: Pruritus With Chronic Liver Disease
Interventions: DRUG: Nalfurafine Hydrochloride (TRK-820)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cervical Lidocaine for Intrauterine Device Insertion Pain
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: 2% lidocaine gel|DRUG: Water based lubricant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Transcutaneous Electrical Nerve Stimulation on Cortical Excitability in the Primary Motor Cortex in Healthy Adults
Status: COMPLETED
Conditions: Transcutaneous Electrical Nerve Stimulation
Interventions: DEVICE: transcutaneous electrical nerve stimulation, TENS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Genetically Modified T-cell Immunotherapy in Treating Patients With Relapsed/Refractory Acute Myeloid Leukemia and Persistent/Recurrent Blastic Plasmacytoid Dendritic Cell Neoplasm
Status: ACTIVE_NOT_RECRUITING
Conditions: Adult Acute Myeloid Leukemia in Remission|Acute Biphenotypic Leukemia|Early Relapse of Acute Myeloid Leukemia|Late Relapse of Acute Myeloid Leukemia|Recurrent Adult Acute Myeloid Leukemia|Secondary Acute Myeloid Leukemia|Blastic Plasmacytoid Dendritic Cell Neoplasm|Acute Myeloid Leukemia|Adult Acute Lymphoblastic Leukemia|Interleukin-3 Receptor Subunit Alpha Positive|Minimal Residual Disease|Refractory Acute Myeloid Leukemia|Untreated Adult Acute Myeloid Leukemia
Interventions: DRUG: cyclophosphamide|BIOLOGICAL: Autologous CD123CAR-CD28-CD3zeta-EGFRt-expressing T Lymphocytes|OTHER: laboratory biomarker analysis|BIOLOGICAL: Allogeneic CD123CAR-CD28-CD3zeta-EGFRt-expressing T-lymphocytes|DRUG: Fludarabine Phosphate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transcranial Magnetic Stimulation (TMS) in Obesity
Status: UNKNOWN
Conditions: Obesity|Food Craving|Appetite and General Nutritional Disorders
Interventions: DEVICE: High frequency repetitive dTMS|DEVICE: Low frequency repetitive dTMS|DEVICE: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Donor-Derived CD5 CAR T (CT125B) Cells for Relapsed or Refractory T- Cell Acute Lymphoblastic Leukemia/Lymphoma
Status: UNKNOWN
Conditions: T-Cell Acute Lymphoblastic Leukemia/Lymphoma
Interventions: BIOLOGICAL: CD5 CAR T (CT125B)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of Tracheostomy on Lung Deposition in Spontaneously Breathing Patient
Status: COMPLETED
Conditions: Tracheostomized Patients
Interventions: OTHER: Nebulization through the tracheostomy|OTHER: Nebulization through the mouth
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Switch Study to Evaluate F/TAF in HIV-1 Positive Participants Who Are Virologically Suppressed on Regimens Containing FTC/TDF
Status: COMPLETED
Conditions: HIV-1 Infection
Interventions: DRUG: FTC/TDF|DRUG: F/TAF|DRUG: Allowed third antiretroviral agent|DRUG: FTC/TDF Placebo|DRUG: F/TAF Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The BEAR III Trial for Bridge-Enhanced ACL (Anterior Cruciate Ligament) Restoration
Status: ACTIVE_NOT_RECRUITING
Conditions: Anterior Cruciate Ligament Injury|Anterior Cruciate Ligament Rupture
Interventions: DEVICE: Bridge-Enhanced ACL Restoration (BEAR)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RSA-measured in Vivo Migration and Micromotion in the DePuy Tri-Lock, Corail and Deltamotion Hip Replacement Components
Status: UNKNOWN
Conditions: Hip Osteoarthritis
Interventions: DEVICE: DePuy Tri-Lock® femoral stem + Deltamotion® acetabular component|DEVICE: DePuy Corail® femoral stem + Deltamotion® acetabular component
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study Of Zelboraf (Vemurafenib) in Patients With Locally-Advanced, Unresectable, Stage IIIc Or Metastatic Melanoma and Activating Exon 15 BRAF Mutations Other Than V600E
Status: TERMINATED
Conditions: Malignant Melanoma
Interventions: DRUG: Vemurafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hydroxytriptolide in Active Rheumatoid Arthritis Patients With an Inadequate Response to Methotrexate
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: LTS 0.25mg|DRUG: LTS 0.5mg|DRUG: LTS 1.0mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cognitive Improvement After Carotid Stenting in Hyperbaric Oxygen Therapy Trial
Status: NOT_YET_RECRUITING
Conditions: Carotid Stenosis|Cognitive Impairment|Hyperbaric Oxygen Therapy|Stent Implantation
Interventions: PROCEDURE: Hyperbaric oxygen therapy|DRUG: Standard medical treatment|BEHAVIORAL: Risk factor management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Antioxidant Dentifrice on Gingivitis
Status: COMPLETED
Conditions: Gingivitis
Interventions: DRUG: Experimental toothpaste|DRUG: Control toothpaste
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Creatine Safety and Tolerability in Premanifest HD: PRECREST
Status: COMPLETED
Conditions: Huntington Disease
Interventions: DRUG: Creatine monohydrate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Neuromobilization on Median Nerve
Status: RECRUITING
Conditions: Median Nerve|Neuromobilization|Stiffness
Interventions: OTHER: Neuro mobilization|OTHER: Sham neuro mobilization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study to Understand the Effect and Safety of the Study Medicine PF-07817883 in Adults Who Have Symptoms of COVID-19 But Are Not Hospitalized
Status: COMPLETED
Conditions: SARS-CoV-2 Infection
Interventions: DRUG: PF-07817883|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Surgery for Early Lung Cancer With Preoperative Erlotinib (Tarceva): A Clinical Phase II Trial (SELECT)
Status: COMPLETED
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: Erlotinib|DRUG: Erlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Laparoscopic Peritoneal Lavage for Perforated Diverticulitis: A National Registry - Based Study
Status: COMPLETED
Conditions: Diverticular Disease of Colon|Diverticulitis, Colonic|Peritonitis|Gastrointestinal Diseases|Digestive System Disease
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study to Evaluate the Safety of Novartis MenACWY Conjugate Vaccine When Administered With Routine Infant Vaccinations to Healthy Infants
Status: COMPLETED
Conditions: Meningitis|Meningococcal Infection
Interventions: BIOLOGICAL: MenACWY-CRM197|BIOLOGICAL: DTaP (Diptheria, Tetanus, Pertussis) Vaccine|BIOLOGICAL: Hib (Haemophilus influenza b) Vaccine|BIOLOGICAL: IPV (Inactivated Polio Vaccine) Vaccine|BIOLOGICAL: Pneumococcal conjugate Vaccine|BIOLOGICAL: MMR (Measles, Mumps, and Rubella) Vaccine|BIOLOGICAL: Varicella Vaccine|BIOLOGICAL: Hepatitis A Virus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: An Open-label Study to Evaluate the Effects of Concurrent Administration of Vaginal Antimycotic Medication Miconazole Nitrate on the Pharmacokinetics of Nestorone and Ethinyl Estradiol Delivered by a Contraceptive Vaginal Ring in Normal Ovulating Women
Status: COMPLETED
Conditions: Antifungal Drug Adverse Reaction
Interventions: DRUG: NES/EE CVR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of an Altered Peptide Ligand (NBI-5788) in Patients With Relapsing Multiple Sclerosis (MS)
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DRUG: NBI-5788
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: SHR-1210 Combined With Apatinib in Treatment of ED-SCLC After Failure of First Line Standard Therapy
Status: COMPLETED
Conditions: Small-cell Lung Cancer
Interventions: DRUG: SHR-1210|DRUG: Apatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Evaluation of Use of Topical Ocular Hypotensive Medication by Compliance
Status: COMPLETED
Conditions: Glaucoma|Ocular Hypertension
Interventions: DRUG: travoprost, latanoprost, or bimatoprost|DRUG: Additional ocular hypotensive medication
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Confocal Endomicroscopy for Barrett's Esophagus
Status: COMPLETED
Conditions: Barrett's Esophagus|Esophageal Adenocarcinoma
Interventions: DEVICE: confocal laser endomicroscopy (CLE)|DEVICE: standard endoscopy (EGD)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Therapy With Abraxane and 5-Fluorouracil, Epirubicin, Cyclophosphamide (FEC) for Patients With Breast Cancer
Status: COMPLETED
Conditions: Breast Neoplasms
Interventions: DRUG: Nanoparticle albumin bound paclitaxel followed by FEC
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hypertonic Saline in NCFB
Status: RECRUITING
Conditions: Bronchiectasis|Non-cystic Fibrosis Bronchiectasis
Interventions: DRUG: 7% Hypertonic Saline via nebulization
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Enteral Resuscitation In Intensive Care Pilot- Study
Status: RECRUITING
Conditions: Electrolyte Imbalance|Volume Overload|Hyperosmolality
Interventions: DRUG: Enteral Dose Form|DRUG: Intravenous Infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Point-of-care Ultrasound Abnormalities in Early Onset Preeclampsia
Status: RECRUITING
Conditions: Preeclampsia|Pulmonary Edema|Cardiac Function
Interventions: DIAGNOSTIC_TEST: Lung ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effect of Neonatal Feeding Modalities on Splanchnic Oxygenation
Status: COMPLETED
Conditions: Intrauterine Growth Retardation|Feeding Patterns|Splanchnic Hypoperfusion
Interventions: OTHER: The effect of drip versus intermittent feeding on splanchnic oxygenation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study to Analyze the Aerobic Performance Efficacy of Chronic Intake With a β-alanine Supplement in Recreational Cyclists
Status: COMPLETED
Conditions: Beta Alanine Supplementation
Interventions: DIETARY_SUPPLEMENT: Beta Alanine high dose|DIETARY_SUPPLEMENT: Beta Alanine low dose|DIETARY_SUPPLEMENT: Control product
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: A Dual Tandem Study - SC vs. CAD-EYE vs. CAD-EYE With G-EYE
Status: UNKNOWN
Conditions: Adenoma|Colo-rectal Cancer
Interventions: DEVICE: Standard Colonoscopy|DEVICE: CAD-EYE|DEVICE: G-EYE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Optimizing Gestational Weight Gain, Birth Weight and Other Perinatal Outcomes Among Pregnant Women at Risk of Hypertension in Pregnancy
Status: UNKNOWN
Conditions: Hypertension, Pregnancy-Induced|Hypertension, Essential Hypertension|Hypertension; Pre-Eclampsia|Hypertension in Pregnancy
Interventions: DEVICE: Self monitoring of blood pressure using Health Gauge Device and monthly monitoring of weight gain
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to Test the Long-term Treatment of Bimekizumab in Study Participants With Moderate to Severe Hidradenitis Suppurativa
Status: ACTIVE_NOT_RECRUITING
Conditions: Hidradenitis Suppurativa
Interventions: DRUG: Bimekizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Causal Inference Research of Resistant Hypertension Treatment With Chinese Approach in a Cohort Study
Status: COMPLETED
Conditions: Primary Hypertension|Hypertension, Resistant to Conventional Therapy
Interventions: DRUG: Herbs|DRUG: Antihypertensive drugs
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Ophiocephalus Striatus Extract on Levels of IGF-1, Albumin, and MNA Score in Elderly With Malnutrition
Status: COMPLETED
Conditions: Malnutrition
Interventions: DIETARY_SUPPLEMENT: Ophiochepalus striatus extract|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Stellate Ganglion Block in Patients With Cerebral Small Vessel Disease
Status: NOT_YET_RECRUITING
Conditions: Cerebral Small Vessel Diseases
Interventions: BEHAVIORAL: Rehabilitation therapy|PROCEDURE: Stellate ganglion block|DRUG: Lidocaine Hydrochloride|BEHAVIORAL: placebo injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Oral Bioavailability of GLPG0555 in Different Solid Formulations
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: GLPG0555 solid dispersion|DRUG: GLPG0555 nanosuspension
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Computed Tomography Enterography (CTE) Versus Capsule Endoscopy for Overt, Obscure Gastrointestinal (GI) Bleeding
Status: WITHDRAWN
Conditions: Recurrent Gastrointestinal Bleeding
Interventions: DEVICE: Capsule Endoscopy|RADIATION: CT Enterography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: INDIGO-2: The Effect of High Water Intake on Glucose Regulation in Low-drinkers
Status: COMPLETED
Conditions: Dehydration|Diabetes Mellitus, Type 2
Interventions: OTHER: Water Intake
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study Evaluating the Efficacy and Safety of Idelalisib in Combination With Bendamustine and Rituximab for Previously Treated Chronic Lymphocytic Leukemia (CLL) (Tugela )
Status: COMPLETED
Conditions: Chronic Lymphocytic Leukemia
Interventions: DRUG: Idelalisib|DRUG: Rituximab|DRUG: Bendamustine|DRUG: Placebo to match idelalisib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evolocumab Compared to LDL-C Apheresis in Patients Receiving LDL-C Apheresis Prior to Study Enrollment
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: BIOLOGICAL: Evolocumab|PROCEDURE: Low-density Lipoprotein Cholesterol (LDL-C) Apheresis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Total Intravenous Versus Inhalational Anesthesia- A Geriatric Anesthesia Study
Status: RECRUITING
Conditions: Neurocognitive Disorders|Anesthesia|Post-operative Delirium|Post-operative Cognitive Dysfunction
Interventions: DRUG: Sevoflurane|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Musculoskeletal System in Caregivers of Rehabilitation Patients
Status: RECRUITING
Conditions: Caregiver Burden|Stroke|Cerebral Palsy|Neurologic Disorder|Pediatric Disorder|Orthopedic Disorder
Interventions: OTHER: Assessment study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Posterior Transversus Abdominis Plane Block Versus Erector Spinae Plane Block as a Part of Multimodal Analgesia in Patients Undergoing Percutaneous Nephrolithotomy
Status: UNKNOWN
Conditions: Analgesia
Interventions: OTHER: Posterior TAP block|OTHER: ESPB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Supplemental Protein And Resistance Training Adaptations
Status: COMPLETED
Conditions: Hypertrophy
Interventions: DIETARY_SUPPLEMENT: Placebo beverage|DIETARY_SUPPLEMENT: Protein-polyphenol beverage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Disitamab Vedotin With Pembrolizumab vs Chemotherapy in Previously Untreated Urothelial Cancer Expressing HER2
Status: RECRUITING
Conditions: Urothelial Carcinoma
Interventions: DRUG: disitamab vedotin|DRUG: pembrolizumab|DRUG: gemcitabine|DRUG: cisplatin|DRUG: carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Efficacy and Safety of HLX10 in Combination With HLX07 in Patients With Advanced Head and Neck Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Head and Neck Squamous Cell Carcinoma
Interventions: DRUG: HLX10|DRUG: HLX07|DRUG: HLX07 placebo|DRUG: Cisplatin/Carboplatin|DRUG: 5-FU
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Treatment of Patients With Type 1 Diabetes Mellitus With Autologous Tolerogenic Dendritic Cells
Status: UNKNOWN
Conditions: Diabetes Mellitus
Interventions: BIOLOGICAL: Autologous tolerogenic dendritic cells|OTHER: Standard treatment according to the clinical protocols
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparative Study of Botulinum Neurotoxin Type A in Treatment of Moderate to Severe Glabellar Frown Lines
Status: COMPLETED
Conditions: Glabellar Frown Lines
Interventions: DRUG: Botulinum toxin type A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cabozantinib in Patients With Locally Advanced or Metastatic Urothelial Cell Carcinoma.
Status: TERMINATED
Conditions: Urothelial Carcinoma
Interventions: DRUG: Cabozantinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Condensed Digital Prolonged Exposure for Individuals Treated Within Somatic Trauma Care.
Status: NOT_YET_RECRUITING
Conditions: Post Traumatic Stress Disorder|Acute Stress Disorder
Interventions: BEHAVIORAL: Condensed Internet delivered prolonged exposure (CIPE)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II/III Randomized, Double-Blind, Placebo-Controlled Study of Dehydroepiandrosterone in Women With Mild to Moderate Systemic Lupus Erythematosus
Status: COMPLETED
Conditions: Systemic Lupus Erythematosus
Interventions: DRUG: dehydroepiandrosterone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: C-arm Cone Beam CTP Guided Cerebrovascular Interventions
Status: NOT_YET_RECRUITING
Conditions: Acute Ischemic Stroke
Interventions: DIAGNOSTIC_TEST: C-Arm Cone Beam Computed Tomography|DIAGNOSTIC_TEST: Multi-detector Computed Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Pilot Trial of Autologous Tumor Infiltrating Lymphocytes (LN-144) for Patients With Metastatic Uveal Melanoma
Status: RECRUITING
Conditions: Uveal Melanoma|Melanoma|Metastatic Uveal Melanoma|Metastatic Melanoma
Interventions: BIOLOGICAL: Lifileucel (LN-144)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Magnetic Resonance Imaging of Gynecologic Malignancies Involving the Vagina
Status: COMPLETED
Conditions: Vaginal Cancer
Interventions: PROCEDURE: Magnetic Resonance Imaging (MRI)|PROCEDURE: Diffusion Weighted Magnetic Resonance Imaging (DWMR)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: AZD1775 Combined With Olaparib in Patients With Refractory Solid Tumors
Status: COMPLETED
Conditions: Refractory Solid Tumours|Relapsed Small Cell Lung Cancer (SCLC)
Interventions: DRUG: AZD1775|DRUG: Olaparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Dose Escalation Study of MLN7243 (TAK-243) in Adult Participants With Advanced Solid Tumors
Status: TERMINATED
Conditions: Advanced Malignant Solid Tumors
Interventions: DRUG: MLN7243
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: First-in-human Trial of PhOx430, a First-in-class Acetylglucosaminyltransferase V Inhibitor, in Advanced Solid Tumours
Status: RECRUITING
Conditions: Malignant Tumor|Advanced Solid Tumor|Glioblastoma Multiforme|Metastatic Cancer
Interventions: DRUG: PhOx430|DRUG: PhOx430
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomised Pilot Study of the REVISiT Intervention
Status: COMPLETED
Conditions: Patient Safety|Inappropriate Prescribing|Medication Errors
Interventions: OTHER: REVISiT intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Bioequivalence Study Doxycycline Tablets and Monodox Capsules Under Fasting Conditions
Status: COMPLETED
Conditions: To Determine Bioequivalence Under Fasting Conditions
Interventions: DRUG: Doxycycline Monohydrate|DRUG: Monodox
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Phase II Tularemia Vaccine Comparison
Status: COMPLETED
Conditions: Tularaemia
Interventions: OTHER: Placebo|BIOLOGICAL: Undiluted Francisella tularensis live attenuated vaccine|BIOLOGICAL: Undiluted Francisella tularensis live attenuated vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Rituximab and Oblimersen in Treating Patients With Stage II, Stage III, or Stage IV Follicular Non-Hodgkin's Lymphoma
Status: TERMINATED
Conditions: Stage III Grade 1 Follicular Lymphoma|Stage III Grade 2 Follicular Lymphoma|Stage III Grade 3 Follicular Lymphoma|Stage IV Grade 1 Follicular Lymphoma|Stage IV Grade 2 Follicular Lymphoma|Stage IV Grade 3 Follicular Lymphoma
Interventions: BIOLOGICAL: oblimersen sodium|BIOLOGICAL: rituximab|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Characterize the Efficacy of a Dual Active Dentifrice for the Relief of Dentin Hypersensitivity
Status: COMPLETED
Conditions: Dentin Hypersensitivity|Dentin Sensitivity
Interventions: OTHER: Potassium Nitrate|OTHER: Stannous Fluoride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Chronic Myelod Leukemia Registry at Asan Medical Center
Status: TERMINATED
Conditions: Leukemia, Chronic Myeloid|Myeloid Leukemia, Chronic, Accelerated Phase|Myeloid Leukemia, Chronic, Chronic Phase
Interventions: OTHER: Diagnosed as CML
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pre-eclampsia and Future Cardiovascular Health: An Underused Opportunity to Improve Family Health
Status: RECRUITING
Conditions: Pre-Eclampsia|Cardiovascular Diseases|Cardiovascular Risk Factor|Gestational Hypertension
Interventions: BEHAVIORAL: Face-to-face and web-based lifestyle intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Assessing Environmental Factors in Healthcare Facilities in Order to Improve the Experience of Patients, Staff, and the Quality of Imaging Procedures
Status: ACTIVE_NOT_RECRUITING
Conditions: Healthcare Facility Environment - Imaging
Interventions: OTHER: Light perception|OTHER: Sound perception|OTHER: Smell perception|OTHER: Vibration perception|OTHER: Voice activation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Effectiveness of an Online Support Group in Enhancing Recovery Identity and Health-Related Quality of Life
Status: COMPLETED
Conditions: Ovarian Cancer
Interventions: BEHAVIORAL: mobile online support group (experiment group)|BEHAVIORAL: offline support group (control group)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of Recovery From Drug-Induced Lymphopenia Using Cytomegalovirus-specific T-cell Adoptive Transfer
Status: COMPLETED
Conditions: Glioblastoma
Interventions: BIOLOGICAL: CMV-ALT + CMV-DCs|BIOLOGICAL: CMV-ALT + Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Oval-8 Splinting Versus Standardized Treatment With Tee Pee or Forearm Based Thumb Spica Splinting
Status: WITHDRAWN
Conditions: Carpometacarpal (CMC) Joint Arthritis
Interventions: DEVICE: Oval-8 Splint|DEVICE: Tee Pee Splint|DEVICE: Forearm Based Splint
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Use of Ointments in Prevention of Catheter Related Infections in PD
Status: COMPLETED
Conditions: End Stage Renal Disease
Interventions: DRUG: Mupirocin ointment|DRUG: Polysporin Triple
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: To Investigate the Absorption, Metabolism, Excretion, Absolute Bioavailability, and Immunogenicity of GX-I7 in Healthy Volunteers
Status: UNKNOWN
Conditions: Leukopenia
Interventions: DRUG: GX-I7 or [14C] GX-I7
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Salsalate on Bed Rest-Induced Vascular Dysfunction
Status: COMPLETED
Conditions: Insulin Resistance
Interventions: DRUG: salsalate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: How do Alpha Oscillations Shape the Perception of Pain? - An EEG-based Neurofeedback Study
Status: COMPLETED
Conditions: Experimental Pain in Healthy Human Subjects
Interventions: BEHAVIORAL: attention right training, ARTNF|BEHAVIORAL: attention left training, ALTNF|BEHAVIORAL: sham attention right training, ARTsham|BEHAVIORAL: sham attention left training, ALTsham
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Characterization of Resistance Against Live-attenuated Diarrhoeagenic E. Coli
Status: COMPLETED
Conditions: Diarrhea|Gastroenteritis|Bacterial Infections|Escherichia Coli Infections
Interventions: BIOLOGICAL: E. coli strain E1392-75-2A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Feasibility Study of Confocal Microendoscopy in the Evaluation of Gastrointestinal Neoplasia -Project 1
Status: TERMINATED
Conditions: GERD|Barrett's Esophagus
Interventions: DRUG: Fluorescein|DRUG: Proflavine hemisulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Medical Therapies for Chronic Post-Traumatic Headaches
Status: TERMINATED
Conditions: Headache
Interventions: DRUG: Placebo|DRUG: Propranolol|DRUG: Amitriptyline|DRUG: Topiramate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Compared With 2 Different Ablation Strategies Clinical Outcome for Treating Patients With Paroxysmal Atrial Fibrillation
Status: UNKNOWN
Conditions: Paroxysmal Atrial Fibrillation
Interventions: PROCEDURE: CPVI Group|PROCEDURE: CPVI+LARA Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized, Controlled, Double-blind Clinical Trial Comparing the Efficacy and Safety of Chemoprophylaxis With Hydroxychloroquine in Patients Under Biological Treatment and / or JAK Inhibitors in the Prevention of SARS-CoV-2 Infection
Status: WITHDRAWN
Conditions: COVID 19|Immunomediated Inflammatory Disease in Treatment With Biological Agents and / or Jak Inhibitors
Interventions: DRUG: Hidroxicloroquina|DRUG: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Fish Oil on Athlete's Executive Function
Status: TERMINATED
Conditions: Brain Health|Brain Function|Brain Development
Interventions: DIETARY_SUPPLEMENT: Fish Oil|DIETARY_SUPPLEMENT: Safflower Oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: mHealth to Increase Measles Immunization - a Randomized Controlled Trial in Guinea-Bissau
Status: UNKNOWN
Conditions: Measles
Interventions: OTHER: SMS reminder message|OTHER: Voice call + SMS message
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Prn Budesonide/Formoterol Versus Regular Budesonide/Formoterol Plus Prn Terbutaline in Mild-Moderate Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: budesonide/formoterol combination (PRN)|DRUG: budesonide/formoterol combination|DRUG: placebo|DRUG: terbutaline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy, Safety, and Drug Concentration of Certolizumab Pegol (CZP) in Children and Adolescent Study Participants With Moderate to Severe Chronic Plaque Psoriasis (PSO)
Status: RECRUITING
Conditions: Moderate Chronic Plaque Psoriasis|Severe Chronic Plaque Psoriasis|Mixed Guttate/Plaque Psoriasis
Interventions: DRUG: Certolizumab pegol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Evaluation of Orange Peel Fermentation on Body Fat Lowering Efficacy in Adults
Status: RECRUITING
Conditions: Overweight|Fatty Liver Disease
Interventions: DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: orange peel fermentation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Predictors for Response to Dose-dense Docetaxel and Epirubicin Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Stage III Breast Cancer AJCC V7
Interventions: OTHER: epirubicin/docetaxel sequential
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Effect of Different Fish Oils on Omega-3 Index (CetoIndex)
Status: UNKNOWN
Conditions: Healthy Volunteers
Interventions: DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: Ceto 10|DIETARY_SUPPLEMENT: Fish oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Improvement of Sensibility in the Foot in Diabetic Patients Induced by EMLA-application to the Lower Leg
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: DRUG: EMLA cream|DRUG: EMLA cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Influence of Peripheral Androgen Conversion at Women Adult Acne
Status: UNKNOWN
Conditions: Acne|Quality of Life
Interventions: DRUG: treatment azelaic acid (azelan)|DRUG: dorspirenone/ethynil estradiol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of Adsorption Tetanus-diphtheria-acellular Pertussis (DTaP) Vaccine in Healthy 3 to 5 Months Infants
Status: COMPLETED
Conditions: Pertussis
Interventions: BIOLOGICAL: DTaP Vaccine A|BIOLOGICAL: DTaP Vaccine B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Immunogenicity and Safety of Fractional Doses of Yellow Fever Vaccines (YEFE)
Status: COMPLETED
Conditions: Yellow Fever
Interventions: BIOLOGICAL: Stamaril, Sanofi Pasteur|BIOLOGICAL: Yellow fever vaccine, Bio-Manguinhos|BIOLOGICAL: Yellow fever vaccine, Institut Pasteur|BIOLOGICAL: Yellow fever vaccine, Chumakov Institute|BIOLOGICAL: Yellow fever vaccine, Chumakov Institute|BIOLOGICAL: Yellow fever vaccine, Chumakov Institute
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Test How Iclepertin is Taken up in the Blood of People With and Without Liver Problems
Status: COMPLETED
Conditions: Hepatic Insufficiency
Interventions: DRUG: BI 425809 (iclepertin)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sintilimab Combined With Anlotinib for Perioperative Non-small Cell Lung Cancer Based on MRD Evaluation
Status: RECRUITING
Conditions: Non-small Cell Lung Cancer|Minimal Residual Disease|Immunotherapy|Anti-angiogenesis
Interventions: DRUG: sintilimab combined with anlotinib|DRUG: sintilimab monotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Intervention of High Tension in the Pancreatic Duct on the Outcome of Severe Biliary Pancreatitis
Status: UNKNOWN
Conditions: ERCP
Interventions: PROCEDURE: experiment|PROCEDURE: control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acute Effects of Organic Guayusa Extract
Status: COMPLETED
Conditions: Acute Physiological Effects of Organic Guayusa Extract
Interventions: DIETARY_SUPPLEMENT: Acute Moderate-Dose Guayusa Extract Supplementation|DIETARY_SUPPLEMENT: Acute High-Dose Guayusa Extract Supplementation|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Comparison of Prophylactic Photobiomodulation Protocols in Chemoinduced Oral Mucositis in Oncology Patients
Status: RECRUITING
Conditions: Oral Mucositis|Chemotherapeutic Toxicity|Childhood Cancer
Interventions: DEVICE: Diode Semiconductor, Duo|DEVICE: Gemini laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Ridge Preservation With FDBA (Freeze Dried Bone Allograft) Using Dexamethasone vs. Saline
Status: RECRUITING
Conditions: Bone Graft|Tooth Extraction
Interventions: DRUG: Dexamethasone 4mg/ml solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Drug Interaction Study of KW-6356 and Clarithromycin or Rifampicin
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DRUG: KW-6356|DRUG: Clarithromycin|DRUG: Rifampicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preemptive Analgesia for Hemorrhoidectomy
Status: UNKNOWN
Conditions: Hemorrhoidectomy
Interventions: PROCEDURE: Hemorrhoidectomy|DRUG: Ketoprophenum|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Effectiveness of Combined Intra-articular and Intra-osseus Injection VS a Single Intra-articular Injection of Bone Marrow Concentrate
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: BIOLOGICAL: Bone Marrow Concentrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigating Pathways Between Maternal Nutritional Status, Breastmilk Composition, and Infant Linear Growth in Rural Pakistan
Status: COMPLETED
Conditions: Breast Milk Collection|Infant Development
Interventions: DIETARY_SUPPLEMENT: Multiple micronutrients (UNIMMAP composition)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Modified Folinic Acid-Fluorouracil-Oxaliplatin Regimen + Capecitabine for Elderly With Metastatic Gastric Cancer
Status: UNKNOWN
Conditions: Metastatic Gastric Cancer
Interventions: DRUG: FOLFOX|DRUG: Capecitabine
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: To Assess the Effects of Valsartan on Albuminuria/Proteinuria in Hypertensive Patients With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Microalbuminuria|Proteinuria
Interventions: DRUG: valsartan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lumbar Plexus Block Upon the Incidence of Ischemic Cardiovascular Events in Elderly Patients With Hip Fracture
Status: COMPLETED
Conditions: Hip Fractures|Perioperative Myocardial Ischemia
Interventions: PROCEDURE: Continuous lumbar plexus (LP) block analgesia|DRUG: Intravenous patient-controlled analgesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT