pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Patient-centered Trial of a Process-of-care Intervention in Hospitalized AKI Patients: the COPE-AKI Trial
Status: RECRUITING
Conditions: Acute Kidney Injury
Interventions: OTHER: Study Physician/Advance Practice Provider|OTHER: Nurse Navigator|OTHER: Pharmacist|OTHER: Patient Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Treatment Combination of Durvalumab, Tremelimumab and Enfortumab Vedotin or Durvalumab and Enfortumab Vedotin in Patients With Muscle Invasive Bladder Cancer Ineligible to Cisplatin or Who Refuse Cisplatin
Status: RECRUITING
Conditions: Muscle Invasive Bladder Cancer
Interventions: DRUG: Durvalumab|DRUG: Tremelimumab|DRUG: Enfortumab Vedotin|PROCEDURE: Radical Cystectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: IRAF-ABLATION Study: a Multicenter International Retrospective Cohort of Patients With BTK Inhibitors-related AF Treated by Catheter Ablation
Status: NOT_YET_RECRUITING
Conditions: BTKi-induced Atrial Fibrillation|Hematologic Malignancy|Atrial Fibrillation Catheter Ablation
Interventions: PROCEDURE: Atrial fibrillation catheter ablation in a population of BTKi-induced atrial fibrillation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: ANAVEX2-73 for Treatment of Early Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer Disease
Interventions: DRUG: High dose ANAVEX2-73|DRUG: Mid dose ANAVEX2-73|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Long-term Safety Study of Alogliptin Used in Combination With α-glucosidase Inhibitor in Participants With Type 2 Diabetes in Japan
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Alogliptin and voglibose|DRUG: Alogliptin and voglibose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Surgical Conditions During Laparoscopic Bariatric Surgery
Status: COMPLETED
Conditions: Morbid Obesity
Interventions: DRUG: Rocuronium|DEVICE: Insufflation pressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Prospective Study of Nutraceutical Supplements to Support Hair Growth in Females
Status: RECRUITING
Conditions: Hair Thinning
Interventions: DIETARY_SUPPLEMENT: Nutrafol Women's Hair Growth Supplement|DIETARY_SUPPLEMENT: Nutrafol Women's Balance Hair Growth Supplement|DIETARY_SUPPLEMENT: Nutrafol Women's Vegan Hair Growth Supplement|DIETARY_SUPPLEMENT: Nutrafol Women's Postpartum Hair Growth Supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of Mycobacterium w in COVID-19 Positive Patients, Hospitalized But Not Critically Ill
Status: UNKNOWN
Conditions: COVID-19
Interventions: DRUG: Suspension of heat killed (autoclaved) Mycobacterium w|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Tolerance,Pharmacokinetic Characteristics,Safety and Efficacy of ScTIL210 in the Treatment of Melanoma
Status: UNKNOWN
Conditions: Melanoma
Interventions: BIOLOGICAL: Super circulating tumor infiltrating lymphocytes(ScTIL)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rituximab Plus Chemotherapy in Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma
Status: COMPLETED
Conditions: Head and Neck Squamous Carcinoma
Interventions: DRUG: Rituximab|DRUG: Cisplatin|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Selinexor Plus High-Dose Melphalan (HDM) Before Autologous Hematopoietic Cell Transplantation for Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Selinexor|DRUG: Melphalan|DRUG: Dexamethasone|PROCEDURE: Autologous Hematopoietic Cell Transplantation (HCT)|DRUG: Fosaprepitant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radiation Therapy With or Without Chemotherapy After Surgery in Treating Patients With Stage IB or Stage IIA Cervical Cancer
Status: COMPLETED
Conditions: Cervical Cancer
Interventions: BIOLOGICAL: bleomycin sulfate|DRUG: cisplatin|DRUG: fluorouracil|DRUG: ifosfamide|DRUG: methotrexate|DRUG: mitomycin C|DRUG: vinblastine sulfate|DRUG: vindesine|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Hemodynamic Changes of Patients Receiving Atenolol/Bisoprolol
Status: COMPLETED
Conditions: Hypertension|Metabolic Syndrome
Interventions: DRUG: Atenolol|DRUG: Bisoprolol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effect of Enzyme-containing Lozenge on Dental Biofilm Formation, Composition and Functionality
Status: RECRUITING
Conditions: Dental Biofilm Accumulation
Interventions: DIETARY_SUPPLEMENT: Enzyme containing lozenge
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Temozolomide and Thalidomide in Treating Patients With Metastatic, Locally Advanced, or Unresectable Leiomyosarcoma
Status: UNKNOWN
Conditions: Sarcoma
Interventions: DRUG: temozolomide|DRUG: thalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Study to Asses DTPw-HBV/Hib at 15-18 Months (m) and Mencevax™ ACW at 24 to 30 m in Primed Subjects
Status: COMPLETED
Conditions: Infections, Meningococcal
Interventions: BIOLOGICAL: Tritanrix™- HepB|BIOLOGICAL: Hiberix™|BIOLOGICAL: Mencevax™ ACW
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study Of RV-39 In Patients Who Also Have Asthma
Status: TERMINATED
Conditions: Asthma
Interventions: DRUG: fluticasone propionate/salmeterol|DRUG: fluticasone propionate|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of First-line Anti-PD-1/PD-L1 Monoclonal Antibody in Combination With Chemotherapy and Bronchoscopy-assisted Interventional Therapy in Patients With Advanced Central Non-small Cell Lung Cancer
Status: NOT_YET_RECRUITING
Conditions: Advanced Lung Carcinoma|Non-small Cell Lung Cancer
Interventions: DRUG: Anti-PD-1/PD-L1 Monoclonal Antibody，Chemotherapy|DEVICE: Bronchoscopy-assisted Interventional Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Aspirin and Clopidogrel in Patients With Idiopathic Pulmonary Arterial Hypertension
Status: COMPLETED
Conditions: Hypertension, Pulmonary
Interventions: DRUG: Aspirin|DRUG: clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Three Different Ultrasound-guided Nerve Blocks in VATS
Status: UNKNOWN
Conditions: Thoracic Anesthesia|Nerve Block|Pain, Acute
Interventions: PROCEDURE: Paravertebral block|PROCEDURE: ESP block|PROCEDURE: MTP block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Evaluation of Maintenance Therapy Combination Mirvetuximab Soravtansine and Olaparib
Status: RECRUITING
Conditions: Ovary Cancer|Peritoneal Cancer|Fallopian Tube Cancer
Interventions: DRUG: Mirvetuximab Soravtansine|DRUG: Olaparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mental Imagery and Targeted Memory Reactivation in PTSD
Status: RECRUITING
Conditions: Nightmares, REM-Sleep Type|PTSD
Interventions: BEHAVIORAL: Imagery Rehearsal Therapy and Targeted memory reactivation during REM sleep|BEHAVIORAL: Imagery Rehearsal Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Trial of Topical C-82 in Systemic Sclerosis - A Phase I/II Biomarker and Safety Trial
Status: COMPLETED
Conditions: Systemic Scleroderma
Interventions: DRUG: C-82 Topical Gel, 1%|DRUG: C-82 Topical Gel, Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PC MIROIR : Effects of Mirror Therapy in Children With Hemiplegic Cerebral Palsy
Status: COMPLETED
Conditions: Hemiplegic Cerebral Palsy
Interventions: PROCEDURE: mirror therapy|PROCEDURE: bimanual rehabilitation exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Clinical Trial to Evaluate the Safety and Pharmacokinetics of JP-1366 in Healthy Adult Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: JP-1366 20mg tablet|DRUG: JP-1366 20mg capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Outpatient Versus Inpatient Balloon Catheter Induction of Labor
Status: COMPLETED
Conditions: Prolonged Pregnancy
Interventions: OTHER: Intervention is to let patient to go home.|OTHER: Intervention is to observe women in the ward.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study to Evaluate the Effect of Co-administration of Itraconazole or Diltiazem on the Pharmacokinetics of BMS-986177 in Healthy Subjects
Status: COMPLETED
Conditions: Thrombosis
Interventions: DRUG: BMS-986177|DRUG: Itraconazole|DRUG: Diltiazem ER
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Tagraxofusp-erzs, an IL-3 Diphtheria Fusion Protein, in Combination With Gemtuzumab Ozogamicin in Patients With Relapsed/Refractory AML
Status: RECRUITING
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Dose Escalation -tagraxofusp-erzs|DRUG: Dose Expansion at RP2D -tagraxofusp-erzs
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Of Atorvastatin For The Treatment Of High Cholesterol In Patients At High Risk Of Coronary Heart Disease (CHD)
Status: COMPLETED
Conditions: Dyslipidemias
Interventions: DRUG: Atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Orbitofrontal Cortex (OFC) Influence on Addictive Medication Overuse Headache (MOH) Deriving From Migraine
Status: COMPLETED
Conditions: Medication Overuse Headache
Interventions: PROCEDURE: PET (withdrawal)|PROCEDURE: Imaging|PROCEDURE: Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Adipose Derived Mesenchymal Stem Cell Characteristics in Anal Fistulas
Status: COMPLETED
Conditions: Perianal Fistula|Adipose Tissue|Tissue Transplantation
Interventions: PROCEDURE: Injection of autologous adipose tissue in anal fistula
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of SHR0410 in Hemodialysis Patients With Pruritus
Status: UNKNOWN
Conditions: Pruritus
Interventions: DRUG: SHR0410|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Autosomal Dominant Polycystic Kidney Disease (ADPKD) Pain Study
Status: COMPLETED
Conditions: Kidney, Polycystic, Autosomal Dominant
Interventions: PROCEDURE: video thorascopic splanchnicectomy (VSPL)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, False-Positive Reactions and Sensitizing Properties of Leishmania Tropica Skin Test Antigen
Status: COMPLETED
Conditions: Cutaneous Leishmaniasis
Interventions: BIOLOGICAL: Leishmania tropica Skin Test Antigen (LtSTA)|BIOLOGICAL: Leishmania tropica Skin Test Antigen Placebo (Placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SCREENING
Clinical trial: Tool for Fibromyalgia Diagnosis and Effect of Extra Virgin Olive Oil
Status: ACTIVE_NOT_RECRUITING
Conditions: Fibromyalgia
Interventions: DIETARY_SUPPLEMENT: Extra Virgin Olive oil-supplemented Mediterranean Diet Intervention|DIETARY_SUPPLEMENT: Olive oil-supplemented Mediterranean Diet Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Randomized Phase 2 Study of Erlotinib + ARQ 197 Versus Erlotinib + Placebo in Previously Treated Patients With Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)
Status: COMPLETED
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: ARQ 197|DRUG: Erlotinib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Allogeneic Human Bone Marrow Derived Mesenchymal Stem Cells in Localized Prostate Cancer
Status: TERMINATED
Conditions: Prostate Cancer
Interventions: BIOLOGICAL: Allogeneic Human Mesenchymal Stem Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intravenous Lidocaine in the Prevention of Postoperative Vomiting in Elective Tonsil Surgery
Status: COMPLETED
Conditions: Postoperative Nausea and Vomiting|Pain
Interventions: DRUG: Lidocaine|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Haploidentical Natural Killer (NK) Cells in Patients With Relapsed or Refractory Neuroblastoma
Status: TERMINATED
Conditions: Neuroblastoma
Interventions: DRUG: Fludarabine|DRUG: Cyclophosphamide|BIOLOGICAL: Natural Killer Cell Infusion|DRUG: Mesna|DRUG: Interleukin-2
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Platelet Rich Plasma Injection vs Percutaneous Tenotomy for Common Extensor Tendinopathy
Status: WITHDRAWN
Conditions: Lateral Epicondylitis (Tennis Elbow)
Interventions: BIOLOGICAL: Leukocyte rich platelet rich plasma|DEVICE: Percutaneous Tenotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acceptability, Feasibility and Effectiveness of Online Peer Support Group for ART Adherence Among Youth
Status: RECRUITING
Conditions: HIV Disease Progression
Interventions: BEHAVIORAL: WhatsApp peer support group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Standardized CEUS Algorithms for Diagnosis of HCC - Prospective German Multicenter Study
Status: COMPLETED
Conditions: Hepatocellular Carcinoma|Cholangiocarcinoma, Intrahepatic|Liver Cirrhosis|Liver Cancer|Liver Neoplasms|Liver Diseases
Interventions: DIAGNOSTIC_TEST: contrast enhanced ultrasound (CEUS)|DIAGNOSTIC_TEST: MRI|DIAGNOSTIC_TEST: Histology
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Autonomic Neuromodulation by Transcutaneous Nerve Stimulation in Acute Ischaemic Stroke.
Status: COMPLETED
Conditions: Ischemic Stroke|Thrombotic Stroke|Autonomic Dysfunction|Autonomic Imbalance
Interventions: DEVICE: trans-cutaneous auricular sensory stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of 4th Generation Safety-designed CAR T Cells Targeting High-risk and Refractory B Cell Lymphomas
Status: UNKNOWN
Conditions: B-cell Lymphomas
Interventions: GENETIC: Anti-CD19 CAR T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A First-in-human Clinical Trial to Evaluate an Alpha-radiation Imaging Agent
Status: ENROLLING_BY_INVITATION
Conditions: Neuroendocrine Tumor Grade 2|Neuroendocrine Tumor Grade 1
Interventions: DRUG: [203Pb]VMT-α-NET|DEVICE: SPECT/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Hamstring Viscoelasticity and Low Back Pain
Status: COMPLETED
Conditions: Low Back Pain|Athletic Injuries
Interventions: OTHER: Ballistic Stretching Exercise|OTHER: Extender Exercise|OTHER: Kinesiotaping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Home-based Non-invasive Brain Stimulation for Treatment-resistant Depression Feasibility, Efficacy and Biomarker of Treatment Response
Status: RECRUITING
Conditions: Major Depressive Disorder
Interventions: DEVICE: Non-invasive transcranial direct current stimulation (tDCS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Assess the Safety of Continuous IV Administration of Plerixafor and Assess Impact on the Immune Microenvironment in Patients With Pancreatic, Ovarian and Colorectal Adenocarcinomas
Status: TERMINATED
Conditions: Pancreas Cancer
Interventions: DRUG: Plerixafor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: "Diagnostic Yield and Safety of Transbronchial Lung Biopsy Using Cryoprobes Versus Conventional Forceps.
Status: COMPLETED
Conditions: Interstitial Lung Disease
Interventions: PROCEDURE: Biopsy by cryoprobes|PROCEDURE: Biopsy with conventional forceps
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of Vantictumab (OMP-18R5) in Combination With Paclitaxel in Locally Recurrent or Metastatic Breast Cancer
Status: COMPLETED
Conditions: Metastatic Breast Cancer
Interventions: DRUG: Vantictumab combined with paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CyclASol for the Treatment of Signs and Symptoms of Dry Eye Disease (DED)
Status: COMPLETED
Conditions: Dry Eye Disease
Interventions: DRUG: CyclASol topical ocular, eye drops|DRUG: Vehicle topical ocular, eye drops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An Exposure-Based Implementation Strategy to Decrease Clinician Anxiety Around Suicide Prevention
Status: COMPLETED
Conditions: Implementation Science
Interventions: BEHAVIORAL: Exposure Based Implementation Strategy (EBIS)|BEHAVIORAL: Implementation as Usual (IAU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Trial to Reduce Antimicrobial Use in Nursing Home Residents With Alzheimer's Disease and Other Dementias 2.0
Status: RECRUITING
Conditions: Dementia|Alzheimer Disease|Infections
Interventions: BEHAVIORAL: TRAIN AD 2.0
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effect of Acetazolamide on Sleep Disordered Breathing in Lowlanders Older Than 40 Years at Altitude
Status: COMPLETED
Conditions: Altitude Hypoxia
Interventions: DRUG: ACETAZOLAMIDE oral capsule|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study Evaluating the Efficacy and Safety of ABP 959 Compared With Eculizumab in Adult Participants With PNH
Status: COMPLETED
Conditions: Paroxysmal Nocturnal Hemoglobinuria
Interventions: DRUG: ABP 959|DRUG: Eculizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of JNJ-39393406 on Psychometric Performance and Residual Depressive
Status: COMPLETED
Conditions: Depression
Interventions: DRUG: JNJ-39393406|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: DiRectional AthErectomy + Drug CoAted BaLloon to Treat Long, CalcifIed FemoropopliTeal ArterY Lesions
Status: COMPLETED
Conditions: Peripheral Vascular Disease
Interventions: DEVICE: Medtronic HawkOne® or TurboHawk™|DEVICE: Medtronic IN.PACT® Admiral® DCB|DEVICE: Medtronic Spider™ Distal Protection Device (DPD)|DEVICE: Volcano Visions® PV .014" IVUS catheter|DEVICE: Nitinol Stent Placement
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare Tenofovir DF Versus the Combination of Emtricitabine Plus Tenofovir DF for the Treatment of Chronic Hepatitis B in Patients With Normal Alanine Aminotransferase (ALT)
Status: COMPLETED
Conditions: Chronic Hepatitis B
Interventions: DRUG: Tenofovir DF|DRUG: FTC|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Split-tattoo Study Comparing the Safety and Efficacy of 670nm Picosecond Laser Versus 755 nm for Tattoo Removal
Status: COMPLETED
Conditions: Tattoo Removal
Interventions: DEVICE: Cutera enlighten laser|DEVICE: CynoSure PicoSure 755nm laser
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hybrid Closed Loop Effectiveness Trial in Adults With Type 1 Diabetes
Status: NOT_YET_RECRUITING
Conditions: Diabetes Mellitus, Type 1|Diabetes Complications
Interventions: DEVICE: Device specific training|OTHER: Study clinician/educator visit
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: LaGRA Trial in Laparoscopic Cholecystectomy
Status: COMPLETED
Conditions: Regional Anesthesia Morbidity|Gallbladder Stone|Pain
Interventions: DRUG: Levobupivacaine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety Study of a Three-Dose BioThrax® Regimen for Post-Exposure Prophylaxis in Healthy Adults
Status: COMPLETED
Conditions: Anthrax
Interventions: BIOLOGICAL: BioThrax
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: DHA-PQP vs Chloroquine and Primaquine for Radical Cure of Vivax Malaria in Brazil
Status: COMPLETED
Conditions: Malaria, Vivax|Therapeutics
Interventions: DRUG: CQ coadministered with PQ|DRUG: DHA-PQP coadministered with PQ|DRUG: CQ and PQ starting on Day 42|DRUG: DHA-PQP and PQ starting on Day 42
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adherence to Treatment With PegIntron Pen Plus Rebetol in Treatment-naïve Adult Patients With Hepatitis C in Romania (Study P04247)
Status: TERMINATED
Conditions: Hepatitis C, Chronic|Hepatitis C
Interventions: BIOLOGICAL: PegIntron pen (peginterferon alfa-2b; SCH 54031)|DRUG: Rebetol (ribavirin; SCH 18908)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Mercury II - Compare the Efficacy and Safety of Lipid Lowering Agents Atorvastatin and Simvastatin With Rosuvastatin in High Risk Subjects With Type IIa and IIb Hypercholesterolemia
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DRUG: Rosuvastatin|DRUG: Atorvastatin|DRUG: Simvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: a Clinical Trial to Evaluate the Efficacy and Safety of Agnucaston Tablets in the Treatment of Premenstrual Syndrome (PMS)
Status: COMPLETED
Conditions: Premenstrual Syndrome
Interventions: DRUG: extracts of Vitex agnus castus tablets|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Atezolizumab Combined to Preoperative Radio-chemotherapy in Localized Rectal Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Rectal Neoplasms
Interventions: DRUG: Atezolizumab|DRUG: 5-FU based radio-chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Changes of Motor Function Tests in Congenital Myopathy Subjects Treated With Oral Salbutamol as Compared to no Treatment
Status: ENROLLING_BY_INVITATION
Conditions: Congenital Myopathy|Neuromuscular Diseases|Musculoskeletal Diseases|Nemaline Myopathy|Centronuclear Myopathy|Myosin Storage Myopathy
Interventions: DRUG: Salbutamol (as Salbutamol Sulfate) 2 Mg Oral Tablet|DRUG: Salbutamol Only Product in Oral Dose Form
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Cone Beam Kilovoltage Imaging in Patients Receiving Radiation Therapy for Head and Neck Cancer
Status: TERMINATED
Conditions: Head and Neck Neoplasms
Interventions: DEVICE: PTV Reduction
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Treatment of an Acute Deep Vein Thrombosis (DVT) With Either Rivaroxaban or Current Standard of Care Therapy
Status: COMPLETED
Conditions: Deep Vein Thrombosis|Venous Thrombosis
Interventions: DRUG: Rivaroxaban (Xarelto, BAY59-7939)|DRUG: Standard of care
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Outcomes of Pelvic Surgery With and Without Anti-incontinence Procedure in Occult Stress Urinary Incontinence Patients
Status: UNKNOWN
Conditions: Pelvic Organ Prolapse|Stress Urinary Incontinence|Other Specified Urinary Incontinence
Interventions: PROCEDURE: TVT-O|PROCEDURE: Improved reconstruction pelvic surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Fertility and Obstetric Outcomes After Medical Management Versus Surgical Treatment for First-trimester Miscarriage First-trimester Miscarriage
Status: UNKNOWN
Conditions: Medical; Abortion, Fetus
Interventions: OTHER: medical VS surgical evacuation of the uterus
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Efficacy and Safety of Alnuctamab Compared to Standard of Care Regimens in Participants With Relapsed or Refractory Multiple Myeloma (RRMM)
Status: WITHDRAWN
Conditions: Multiple Myeloma
Interventions: DRUG: Alnuctamab|DRUG: Pomalidomide|DRUG: Daratumumab|DRUG: Elotuzumab|DRUG: Carfilzomib|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reciprocating Gait Orthoses for Paraplegia Patients
Status: UNKNOWN
Conditions: Myelomeningocele|Spinal Cord Injury|Spinal Muscular Atrophy
Interventions: DEVICE: RGOs(reciprocating gait orthoses)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Intrathecal Gemcitabine to Treat Neoplastic Meningitis, IT Gemcitabine
Status: TERMINATED
Conditions: Meningitis|Neoplasms
Interventions: DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Pharmacokinetics (PK) and Safety of Staccato Alprazolam in Adolescent Study Participants With Epilepsy
Status: COMPLETED
Conditions: Epilepsy
Interventions: DRUG: Alprazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Randomized Controlled Pilot Trial of Mesalazine in Patients With Irritable Bowel Syndrome
Status: COMPLETED
Conditions: Irritable Bowel Syndrome
Interventions: DRUG: mesalazine|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: RCT of a Brief Video Intervention Targeting Peer Inclusion to Reduce Depression-related Stigma in Adolescents
Status: NOT_YET_RECRUITING
Conditions: Depression|Adolescent - Emotional Problem|Stigma, Social|Help-Seeking Behavior
Interventions: OTHER: brief video
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Effect of Auricular Stimulation on Locomotion in Patients With Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: DEVICE: Percutaneous electrical nerve stimulation|DEVICE: Percutaneous electrical nerve stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Intravenous Ferric Carboxymaltose (FCM) in Patients With Iron Deficiency Anemia (IDA)
Status: COMPLETED
Conditions: Iron Deficiency Anemia
Interventions: DRUG: Ferric Carboxymaltose (FCM)|DRUG: Ferrous Sulfate Tablets|DRUG: IV Iron (standard of care)|DRUG: Ferric Carboxymaltose (FCM)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Young-Onset Colorectal Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Colon Adenocarcinoma|Colorectal Carcinoma|Rectal Adenocarcinoma
Interventions: PROCEDURE: Biospecimen Collection|OTHER: Medical Chart Review|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Natives Engaged in Alzheimers Research - 'Ike Kupuna
Status: RECRUITING
Conditions: Mild Cognitive Impairment|Subjective Cognitive Impairment
Interventions: BEHAVIORAL: Ola Mau i ka Hula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Erythrocytes-Mediated Delivery Of Dexamethasone 21-Phosphate In Steroid-Dependent Ulcerative Colitis
Status: UNKNOWN
Conditions: Ulcerative Colitis
Interventions: DRUG: Dexamethasone 21-phosphate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Whole Blood With CPD Anticoagulant and AS-7/SOLX Additive Solution
Status: COMPLETED
Conditions: Blood Donors
Interventions: DRUG: SOLX (Investigational)|DRUG: AS-3 (Control)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Intermittent Oro-esophageal Tube vs. Nasogastric Tube on Feeding Amount in Stroke Patients
Status: WITHDRAWN
Conditions: Ischemic Stroke
Interventions: DEVICE: Intermittent Oro-esophageal Tube Feeding|DEVICE: Nasogastric Tube Feeding|BEHAVIORAL: comprehensive rehabilitation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: En-Bloc Resection of Bladder Tumors
Status: UNKNOWN
Conditions: Bladder Neoplasm
Interventions: PROCEDURE: En Bloc Resection|PROCEDURE: Conventional Transurethral Resection Bladder Tumor (Mono/Bipolar)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: SGT-53 in Children With Recurrent or Progressive CNS Malignancies
Status: NOT_YET_RECRUITING
Conditions: Childhood CNS Tumor
Interventions: GENETIC: SGT-53|RADIATION: Radiation|DRUG: Irinotecan|DRUG: Temozolomide|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Efficacy and Safety of Voriconazole for the Treatment of Fungal Infections
Status: COMPLETED
Conditions: Candidiasis|Cryptococcosis|Aspergillosis
Interventions: DRUG: Voriconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Cost-efficiëncy of New Imaging Techniques in Patients Suspected of Coronary Artery Disease
Status: RECRUITING
Conditions: Coronary Artery Disease
Interventions: DIAGNOSTIC_TEST: CT-FFR|DIAGNOSTIC_TEST: Angiography-derived FFR|DIAGNOSTIC_TEST: Angiography with invasive FFR-measurements
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effects of a Colon-delivered Multivitamin Supplement on Brain Functioning, Immunometabolic- and Intestinal Markers in Ageing
Status: COMPLETED
Conditions: Cognitive Decline|Aging
Interventions: DIETARY_SUPPLEMENT: Colon-delivered multivitamin supplement|DIETARY_SUPPLEMENT: Placebo capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Relaxation-Response-based Mental Health Promotion - Open and Calm 2013
Status: UNKNOWN
Conditions: Stress Psychological|Stress Physiological|Quality of Life
Interventions: BEHAVIORAL: Relaxation Response-based Mental Health Promotion (RR-MHP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: C-reactive Protein Levels in Acute Apical Abscess Due to Root Canal Infection
Status: UNKNOWN
Conditions: Dentoalveolar Abscess
Interventions: PROCEDURE: ROOT CANAL TREATMENT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Long-term Follow-up Study of Lentiviral-based Gene-edited Immune Cell Therapy
Status: RECRUITING
Conditions: Diffuse Large B Cell Lymphoma|Large B-cell Lymphoma|Primary Mediastinal Large B Cell Lymphoma|Follicular Lymphoma Grade 3A|Follicular Lymphoma Grade 3B
Interventions: GENETIC: Pell's lentiviral-based gene-edited immune cell therapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Effectiveness of Adding the Health Promotion and Rehabilitation for Treatment for Alcohol and Drug Abusers
Status: COMPLETED
Conditions: Alcoholism|Substance-Related Disorders|Smoking|Chronic Disease|Malnutrition
Interventions: BEHAVIORAL: Health promotion activities
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Ribociclib in Combination With NSAI Versus Physician's Choice of Chemotherapy Sequential Endocrine Therapy in HR+/HER2- Advanced Breast Cancer
Status: RECRUITING
Conditions: Advanced Breast Cancer
Interventions: DRUG: physician's choice of chemotherapy sequential Ribociclib combined with NSAI±OFS|DRUG: Ribociclib combined with NSAI±OFS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation Of The Effect Of L. Casei DG® On Vitamin D Absorption In Patients Under Vitamin D Supplementation.
Status: UNKNOWN
Conditions: Vitamin D Deficiency
Interventions: DIETARY_SUPPLEMENT: L. casei DG® (Lactobacillus paracasei CNCM I-1572)|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Laparoscopic Peritoneal Lavage vs Laparoscopic Sigmoidectomy in Perforated Acute Diverticulitis: a Multicenter Prospective Observational Study (STELLA Study)
Status: COMPLETED
Conditions: Acute Diverticulitis
Interventions: PROCEDURE: Laparoscopic Peritoneal Lavage
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pilot Study Of Sirolimus Plus Multiagent Chemotherapy For Relapsed/Refractory Acute Lymphoblastic Leukemia/Lymphoma
Status: TERMINATED
Conditions: Relapsed Lymphoblastic Leukemia|Recurrent Adult Lymphoblastic Lymphoma|Refractory Acute Lymphoblastic Leukemia|Refractory Lymphoblastic Lymphoma
Interventions: DRUG: Sirolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Hyperoncotic and Isooncotic Albumin to Support Blood Loss Replacement
Status: COMPLETED
Conditions: Blood Loss, Surgical|Fluid Retention
Interventions: DRUG: Hyperoncotic Albumin 20%|DRUG: Isooncotic Albumin 5%|DRUG: Ringer's Lactate Crystalloid Solutions (control group)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Validity of Somatosensori Remediation for Postural Control in the Treatment of Ehlers-Danlos Syndrome Hypermobility Type (hEDS)
Status: COMPLETED
Conditions: Ehlers-Danlos Syndrome Hypermobility Type (hEDS)
Interventions: OTHER: Compressive garment and Somatosensori Remediation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Study:Topison (Mometasone Furoate) Versus Two Others Mometasone Furoates
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: Mometasone Furoate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: The Moderating Roles of Social Support, Coping Resources and Personality and Mediating Role of Self-esteem on the Impact of Cognitive Deficit on Neuropsychiatric Symptoms Among Persons With Mild Cognitive Impairment: A Mixed-method Sequential Explanatory Design
Status: COMPLETED
Conditions: Mild Cognitive Impairment|Behavioral Symptoms
Interventions: BEHAVIORAL: Face-to-face interviews
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Fatty Acid Modulation of Brain Function in Older Adults
Status: RECRUITING
Conditions: Aging
Interventions: DIETARY_SUPPLEMENT: High Oleic Acid Diet|DIETARY_SUPPLEMENT: High Palmitic Acid Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Yoga and Mantram for Chronic Pain and PTSD
Status: COMPLETED
Conditions: Post-Traumatic Stress Disorder|Chronic Low Back Pain|Chronic Neck Pain
Interventions: BEHAVIORAL: Yoga and Mantram Repetition|BEHAVIORAL: Veteran Calm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Possible Effect of Inspiratory Muscle Training on Inflammation Markers and Oxidative Stress in Childhood Asthma
Status: COMPLETED
Conditions: Asthma in Children|Children, Adult
Interventions: OTHER: Inspiratory muscle training|OTHER: Used routine medicine|OTHER: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Bupropion for Smokers Recovering From Alcohol Dependence
Status: COMPLETED
Conditions: Smoking Cessation|Alcohol-Related Disorders
Interventions: DRUG: Bupropion|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of VELCADE and Rituxan as Front-line Tx for Low-grade NHL
Status: COMPLETED
Conditions: Non-Hodgkin's Lymphoma
Interventions: DRUG: Rituximab|DRUG: bortezomib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Endurance and Endurance-Strength Training on Inflammatory Markers in Women With Abdominal Obesity
Status: COMPLETED
Conditions: Obesity
Interventions: BEHAVIORAL: Endurance training|BEHAVIORAL: Endurance-strength training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Clinical Efficacy and Safety Evaluation of HCP1904-1 in Essential Hypertension Patients
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: HCP1904-1|DRUG: RLD2001-1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Point-of-Care System for Determination of Bilirubin Capacity in Neonates
Status: COMPLETED
Conditions: Jaundice, Neonatal|Hyperbilirubinemia|Bilirubin-Induced Neurological Dysfunction (BIND)
Interventions: DEVICE: Bilirubin Binding Capacity by Hematofluorometry Validation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Hemodynamic Stability During Carotid Endarterectomy.Comparison of LENOXe™ (Xenon 100% v/v) Versus Sevoflurane
Status: COMPLETED
Conditions: Hemodynamic Stability
Interventions: DRUG: xenon|DRUG: sévoflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study Developed to Evaluate the Effect of ANG-3777 on QT/QTc Interval
Status: UNKNOWN
Conditions: Healthy Volunteer
Interventions: DRUG: ANG-3777 (Therapeutic Dose)|DRUG: ANG-3777 (Supra-therapeutic Dose)|DRUG: Placebo|DRUG: Moxifloxacin Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Safety and Efficacy of Humanized 3F8 Bispecific Antibody (Hu3F8-BsAb) in Patients With Relapsed/Refractory Neuroblastoma, Osteosarcoma and Other Solid Tumor Cancers
Status: TERMINATED
Conditions: Neuroblastoma|Osteosarcoma|Other Solid Tumor Cancers
Interventions: BIOLOGICAL: Humanized 3F8 Bispecific Antibody|OTHER: Blood draw
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effectiveness and Safety of OZURDEX® in Patients With Diabetic Macular Edema But Never Treated
Status: COMPLETED
Conditions: Diabetic Macular Edema
Interventions: DRUG: Dexamethasone Intravitreal Implant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vegetative Monitoring During Brainstem-associated Surgery
Status: COMPLETED
Conditions: Brain Tumor, Recurrent|Vestibular Schwannoma|Brainstem Neoplasm|Brainstem Glioma
Interventions: PROCEDURE: Intraoperative Monitoring during resection of brain tumor
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Investigate Safety of GS-248 and Efficacy on Raynauds' Phenomenon in Systemic Sclerosis
Status: COMPLETED
Conditions: Systemic Sclerosis
Interventions: DRUG: GS-248|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: L-Serine Supplementation in Hereditary Sensory Neuropathy Type 1
Status: COMPLETED
Conditions: Hereditary Sensory and Autonomic Neuropathy Type I
Interventions: DRUG: L-serine|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Moisture Management Liner Effectiveness Study
Status: COMPLETED
Conditions: Amputation Stumps|Amputees|Amputation|Lower Limb Deformities, Congenital|Prosthesis User|Prosthesis
Interventions: DEVICE: Moisture Management Liner|DEVICE: ICE Socket Cooling System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER