pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Influence of Pregnenolone on Exposure Therapy in Obsessive-compulsive Disorder
Status: UNKNOWN
Conditions: Obsessive-compulsive Disorder (OCD)
Interventions: BEHAVIORAL: Exposure therapy with pharmacological facilitation|BEHAVIORAL: Exposure therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Phase I Intratumoral Pbi-shRNA STMN1 LP in Advanced and/or Metastatic Cancer
Status: COMPLETED
Conditions: Advanced Cancer|Metastatic Cancer|Solid Tumors
Interventions: BIOLOGICAL: pbi-shRNA STMN1 LP
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Per Oral Immunotherapy in Severe IgE Mediated Egg, Milk, and Nut Allergy in Adults
Status: COMPLETED
Conditions: Food Allergy
Interventions: DIETARY_SUPPLEMENT: Dietary supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 3 Study of VX-445 Combination Therapy in Cystic Fibrosis (CF) Subjects Heterozygous for F508del and a Gating or Residual Function Mutation (F/G and F/RF Genotypes)
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: ELX/TEZ/IVA|DRUG: IVA|DRUG: TEZ/IVA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Nutritional Supplements in Preventing Weight Loss in Patients With Cancer
Status: COMPLETED
Conditions: Cachexia|Lymphoma|Lymphoproliferative Disorder|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DIETARY_SUPPLEMENT: Juven|DIETARY_SUPPLEMENT: Non-Juven Supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Hormone Therapy in Treating Patients With Rising PSA Levels Following Radiation Therapy for Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: bicalutamide|DRUG: buserelin|DRUG: cyproterone acetate|DRUG: flutamide|DRUG: goserelin|DRUG: leuprolide acetate|DRUG: nilutamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Remotely Delivered Mindfulness-Based Diabetes Education
Status: NOT_YET_RECRUITING
Conditions: Type 2 Diabetes
Interventions: BEHAVIORAL: Remotely delivered Mindfulness-Based Diabetes Education with remote patient monitoring|BEHAVIORAL: Standard Diabetes Self Management Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Trial to Evaluate the Efficacy and Safety of Tarceva and Capecitabine in Advanced Pancreatic Cancer Patients
Status: COMPLETED
Conditions: Metastatic Adenocarcinoma of the Pancreas
Interventions: DRUG: capecitabine + erlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fit Child - Clinical Study on Weight Control
Status: UNKNOWN
Conditions: Overweight|Nutrition Disorder, Child|Weight Change, Body
Interventions: DIETARY_SUPPLEMENT: Probiotic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mini Fluid chAlleNge and End-expiratory Occlusion Test and to Assess flUid responsiVEness in opeRating Room
Status: COMPLETED
Conditions: Hemodynamic Instability|Anesthesia|Surgery
Interventions: DIAGNOSTIC_TEST: End-expiratory occlusion test (EEOT)|OTHER: mini fluid challenge (mFC)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Outcomes Study of the TM Humeral Stem Used in Primary, Total or Hemi Shoulder Arthroplasty
Status: TERMINATED
Conditions: Osteoarthritis|Rheumatoid Arthritis|Post-traumatic Arthritis|Ununited Humeral Head Fracture|Irreducible 3- and 4-part Proximal Humeral Fractures|Avascular Necrosis
Interventions: DEVICE: Trabecular Metal Humeral Stem
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Nicotinamide for Prevention of Pre-malignant Actinic Keratosis in Kidney Transplant Recipients
Status: COMPLETED
Conditions: Actinic Keratoses
Interventions: DRUG: Oral Nicotinamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Stapling Versus 8plate for Correction of Genu Valgus
Status: UNKNOWN
Conditions: Deformity|Genu Valgus
Interventions: DEVICE: 8plate|DEVICE: Staples (Richards, Smith & Nephew)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: To Evaluate Safety and Tolerability After Multiple Oral Doses of AZD1656 in Type 2 Diabetes Patients on Top of Metformin
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: AZD1656|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I/Ib Study of Pembrolizumab With Vorinostat for Patients With Advanced Renal or Urothelial Cell Carcinoma
Status: COMPLETED
Conditions: Renal Cell Carcinoma|Urinary Bladder Neoplasms
Interventions: DRUG: Pembrolizumab|DRUG: Vorinostat
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Telmisartan and Hydrochlorothiazide Antihypertensive Treatment Study in High Sodium Intake Population
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Telmisartan|DRUG: Hydrochlorothiazide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Portable Measurement Methods Combined With Artificial Intelligence in Detection of Atrial Fibrillation
Status: RECRUITING
Conditions: Atrial Fibrillation|Heart Rate Fast|Heart Rate Low|Sinus Rhythm
Interventions: DEVICE: Heart rhythm monitoring with wearable device|OTHER: Blood samples and biomarkers
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Closure After Total Shoulder Arthroplasty: Prineo vs Dermabond
Status: TERMINATED
Conditions: Shoulder Arthritis|Shoulder Arthropathy Associated With Other Conditions
Interventions: DEVICE: 2-Octyl Cyanoacrylate and Mesh|DEVICE: 2-Octyl Cyanoacrylate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: A Study of RO5212054 (PLX3603) in Participants With BRAF V600-Mutated Advanced Solid Tumors
Status: COMPLETED
Conditions: Neoplasms
Interventions: DRUG: RO5212054
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of CBT Microinterventions on Mechanisms of Behavior Change Among Adults With AUD
Status: COMPLETED
Conditions: Alcohol Use Disorder
Interventions: BEHAVIORAL: Control|BEHAVIORAL: Functional Analysis|BEHAVIORAL: Cognitive Restructuring|BEHAVIORAL: Dealing With Cravings
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Folic Acid for Vascular Outcome Reduction In Transplantation (FAVORIT)
Status: COMPLETED
Conditions: Chronic Kidney Disease|Cardiovascular Disease|Death
Interventions: DRUG: High Dose Multivitamin|DEVICE: Low Dose Multivitamin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Three Dimensional Ultrasonographic Detection of Human Ovulation
Status: RECRUITING
Conditions: Ovulation Disorder
Interventions: DRUG: Indomethacin 50 MG|PROCEDURE: Transvaginal ultrasound scans|DIAGNOSTIC_TEST: Finger prick blood test|DIAGNOSTIC_TEST: Urine test
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Maraviroc in Patients Undergoing Non-Myeloablative Allogeneic Stem-Cell Transplantation
Status: COMPLETED
Conditions: Graft-versus-host Disease|Hematopoietic Stem Cell Transplantation
Interventions: DRUG: Maraviroc 150 MG|DRUG: Maraviroc 300 mg|DRUG: Maraviroc 300 mg Phase II
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of an Interactive Robot for the Rehabilitation of the Upper Limb in Children With Cerebral Palsy
Status: COMPLETED
Conditions: Cerebral Palsy
Interventions: OTHER: Robotic-assisted therapy|OTHER: Classical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pembrolizumab and Lenvatinib for the Treatment of Advanced, Unresectable, or Metastatic Gastroesophageal Adenocarcinoma
Status: RECRUITING
Conditions: Advanced Gastric Adenocarcinoma|Advanced Gastroesophageal Junction Adenocarcinoma|Clinical Stage III Gastric Cancer AJCC v8|Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8|Clinical Stage IV Gastric Cancer AJCC v8|Clinical Stage IV Gastroesophageal Junction Adenocarcinoma AJCC v8|Clinical Stage IVA Gastric Cancer AJCC v8|Clinical Stage IVA Gastroesophageal Junction Adenocarcinoma AJCC v8|Clinical Stage IVB Gastric Cancer AJCC v8|Clinical Stage IVB Gastroesophageal Junction Adenocarcinoma AJCC v8|Metastatic Gastric Adenocarcinoma|Metastatic Gastroesophageal Junction Adenocarcinoma|Pathologic Stage III Gastric Cancer AJCC v8|Pathologic Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8|Pathologic Stage IIIA Gastric Cancer AJCC v8|Pathologic Stage IIIA Gastroesophageal Junction Adenocarcinoma AJCC v8|Pathologic Stage IIIB Gastric Cancer AJCC v8|Pathologic Stage IIIB Gastroesophageal Junction Adenocarcinoma AJCC v8|Pathologic Stage IIIC Gastric Cancer AJCC v8|Pathologic Stage IV Gastric Cancer AJCC v8|Pathologic Stage IV Gastroesophageal Junction Adenocarcinoma AJCC v8|Pathologic Stage IVA Gastroesophageal Junction Adenocarcinoma AJCC v8|Pathologic Stage IVB Gastroesophageal Junction Adenocarcinoma AJCC v8|Postneoadjuvant Therapy Stage III Gastric Cancer AJCC v8|Postneoadjuvant Therapy Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8|Postneoadjuvant Therapy Stage IIIA Gastroesophageal Junction Adenocarcinoma AJCC v8|Postneoadjuvant Therapy Stage IIIB Gastroesophageal Junction Adenocarcinoma AJCC v8|Postneoadjuvant Therapy Stage IV Gastric Cancer AJCC v8|Postneoadjuvant Therapy Stage IV Gastroesophageal Junction Adenocarcinoma AJCC v8|Postneoadjuvant Therapy Stage IVA Gastroesophageal Junction Adenocarcinoma AJCC v8|Postneoadjuvant Therapy Stage IVB Gastroesophageal Junction Adenocarcinoma AJCC v8|Unresectable Gastric Adenocarcinoma|Unresectable Gastroesophageal Junction Adenocarcinoma
Interventions: DRUG: Lenvatinib|BIOLOGICAL: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Development, Acceptability and Preliminary Efficacy of an Internet-Based Self-Help Program
Status: COMPLETED
Conditions: Burnout, Professional
Interventions: BEHAVIORAL: An internet-based self-help program with minimal telephone support utilizing Acceptance and Commitment Therapy for alleviating burnout among healthcare workers.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mirror Therapy Versus CIMT on Hand Function in Cerebral Palsy
Status: COMPLETED
Conditions: Hemiplegic Cerebral Palsy|Mirror Hands
Interventions: OTHER: Physical therapy exercises|OTHER: Mirror therapy|OTHER: Constraint Induced Movement Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of Blood Pressure Monitor in Conformance With the ANSI/AAMI SP10
Status: COMPLETED
Conditions: Hypertension
Interventions: DEVICE: Comparison Test to Yuyue Medical BP Meter, YYBP-212
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Online Mindfulness-Based Intervention to Decrease Pre-Procedural Anxiety Before a First-Time Screening Colonoscopy
Status: RECRUITING
Conditions: Colorectal Carcinoma
Interventions: OTHER: Best Practice|OTHER: Medical Chart Review|BEHAVIORAL: Online Mindfulness Meditation|OTHER: Survey Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study to Evaluate the Effectiveness of Tafasitamab in Combination With Lenalidomide Followed by Tafasitamab Monotherapy in Relapsed or Refractory Diffuse Large B-cell Lymphoma Non-transplant Eligible Patients in Italy (PRO-MIND)
Status: RECRUITING
Conditions: DLBCL - Diffuse Large B Cell Lymphoma
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: EDWARDS INTUITY Valve System CADENCE Study
Status: COMPLETED
Conditions: Aortic Valve Disease|Aortic Stenosis
Interventions: DEVICE: EDWARDS INTUITY|DEVICE: Stented aortic bioprostheses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase Ib Study to Evaluate the Safety, Tolerability, and Pharmacokinetics (PK) of Avelumab in Combination With M9241(NHS-IL12) (JAVELIN IL-12)
Status: TERMINATED
Conditions: Advanced Solid Tumors
Interventions: DRUG: Avelumab|DRUG: M9241|DRUG: Avelumab (Once weekly)|DRUG: M9241 (MTD)|DRUG: Avelumab (Expansion cohort)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: IC14 for Treatment of Amyotrophic Lateral Sclerosis
Status: WITHDRAWN
Conditions: Amyotrophic Lateral Sclerosis|Motor Neuron Disease
Interventions: BIOLOGICAL: IC14|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CSP vs EMR for >6mm Superficial Non-ampullary Duodenal Tumors
Status: UNKNOWN
Conditions: Duodenal Tumor
Interventions: PROCEDURE: Endoscopic resection: CSP/p-CSP|PROCEDURE: Endoscopic resection: EMR/EPMR
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Irinotecan Plus Lobaplatin Versus Irinotecan in the Second-line Treatment of Small Cell Lung Cancer
Status: UNKNOWN
Conditions: Small-cell Lung Cancer
Interventions: DRUG: irinotecan plus lobaplatin|DRUG: irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Causal Connection Between Sng and Muscle Acidosis
Status: UNKNOWN
Conditions: Muscle Acidosis
Interventions: DRUG: Phosphate Buffer Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Assessment of the Effects of Atorvastatin Therapy on Myocardial Deformation Characteristics, in Patients With STEMI
Status: COMPLETED
Conditions: Myocardial Infarction
Interventions: DRUG: Atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Omega 3 Polyunsaturated Fatty Acids (PUFA) or Magnesium in Obese Polycystic Ovary Syndrome Patients
Status: SUSPENDED
Conditions: Polycystic Ovary Syndrome|Obesity
Interventions: DRUG: Metformin|DIETARY_SUPPLEMENT: Magnesium|DIETARY_SUPPLEMENT: PUFA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A 12 Week Safety And Efficacy Study Of Sitaxentan Sodium In Japanese Pulmonary Arterial Hypertension Patients
Status: TERMINATED
Conditions: Hypertension, Pulmonary
Interventions: DRUG: Sitaxentan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radiation Therapy Regimens in Treating Patients With Limited-Stage Small Cell Lung Cancer Receiving Cisplatin and Etoposide
Status: ACTIVE_NOT_RECRUITING
Conditions: Lung Cancer
Interventions: RADIATION: Standard Radiation Dose Therapy|DRUG: cisplatin|DRUG: etoposide|RADIATION: High Radiation Dose Therapy|DRUG: carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I/II Dose-escalating Study of the Safety, Tolerability and Efficacy of KIO-301 Administered Intravitreally to Patients With Retinitis Pigmentosa and Choroideremia (ABACUS)
Status: RECRUITING
Conditions: Retinitis Pigmentosa|Choroideremia
Interventions: DRUG: KIO-301
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rehabilitation of Arm Function Using a Biofeedback Method After Stroke
Status: COMPLETED
Conditions: Rehabilitation|Stroke|Biofeedback
Interventions: OTHER: Biofeedback method|OTHER: Health-resort based rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Preoperative Testing of the Anti-Progesterone Mifepristone in Early Stage Breast Cancer
Status: TERMINATED
Conditions: Invasive Breast Cancer|Ductal Carcinoma in Situ
Interventions: DRUG: Mifepristone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Investigate the Pharmacokinetics, Safety and Tolerability Following Single Administration of CHF6001 in Subjects With Mild, Moderate and Severe Liver Impairment in Comparison With Matched Healthy Control Subjects
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: CHF6001
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Natural Killer Cell Therapy (UD TGFbetai NK Cells) and Temozolomide for the Treatment of Stage IV Melanoma Metastatic to the Brain
Status: RECRUITING
Conditions: Clinical Stage IV Cutaneous Melanoma AJCC v8|Metastatic Malignant Neoplasm in the Brain|Metastatic Melanoma|Pathologic Stage IV Cutaneous Melanoma AJCC v8
Interventions: BIOLOGICAL: Natural Killer Cell Therapy|DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy in Treating Patients With Metastatic or Unresectable Solid Tumors
Status: COMPLETED
Conditions: Recurrent Prostate Cancer|Stage IV Prostate Cancer|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: tanespimycin|DRUG: docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Remotely Supervised tDCS for Persistent Post-traumatic Headache
Status: COMPLETED
Conditions: Persistent Post Traumatic Headache|Mild Traumatic Brain Injury
Interventions: DEVICE: transcranial direct current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lung-MAP S1400K: c-MET Positive
Status: COMPLETED
Conditions: Recurrent Squamous Cell Lung Carcinoma|Stage IV Squamous Cell Lung Carcinoma AJCC V7
Interventions: DRUG: ABBV-399
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Self-Fitting Strategies in the Lexie Powered by Bose Hearing Aids
Status: COMPLETED
Conditions: Hearing Loss
Interventions: DEVICE: Intervention A (hearing aid self-fitting with direct adjustment)|DEVICE: Intervention B (hearing aid self-fitting with in-situ fitting)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Physical Activity Program in End-state Liver Disease
Status: COMPLETED
Conditions: End-stage Liver Disease (ESLD)|Liver Transplant|Sarcopenia|Poor Physical Fitness|Cirrhosis|Portal Hypertension
Interventions: OTHER: Nutritional consultation|BEHAVIORAL: Physical training program|BEHAVIORAL: Behavioral modification therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gemcitabine Plus S1 and Tislelizumab in the First Line Therapy of Advanced Biliary Tract Carcinoma
Status: NOT_YET_RECRUITING
Conditions: Biliary Tract Carcinoma
Interventions: DRUG: Gemcitabine|DRUG: S1|DRUG: Tislelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Factors Influencing the Prognosis of Olfactory Dysfunction After Upper Sensation
Status: NOT_YET_RECRUITING
Conditions: Outcome
Interventions: DRUG: methylprednisolone|DRUG: budesonide atomization suspension
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ADVANCED Phase II Trial of Weekly vs 3 Weekly Docetaxel and Cisplatin Followed by Gemcitabine in Non-small-cell Lung Cancer (NSCLC)
Status: COMPLETED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: Docetaxel and cisplatin followed by gemcitabine|DRUG: docetaxel and cisplatin followed by gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study in Healthy Men to Test How BI 1569912 is Processed in the Body
Status: NOT_YET_RECRUITING
Conditions: Healthy
Interventions: DRUG: BI 1569912 (C-14)|DRUG: BI 1569912 (C-13)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Physical and Cognitive Exercises in Nursing Homes: Is Frailty Reversible?
Status: COMPLETED
Conditions: Physical Activity|Elderly
Interventions: OTHER: exercise without visual stimuli|OTHER: excercise with National Geografics|OTHER: Exercise with MemoRide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: A Prospective Single-Arm Multicenter StuDy of the BarE TEmporary SPur StEnt System foR the tREatment of Vascular Lesions Located in the infrapoplitEal Arteries beLow the Knee (DEEPER REVEAL)
Status: RECRUITING
Conditions: Peripheral Arterial Disease|Critical Limb Ischemia
Interventions: DEVICE: Bare Temporary Spur Stent System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Albendazole Plus High Dose Ivermectin for Trichuriasis in Pediatric Patients
Status: COMPLETED
Conditions: Trichuris Infection|Helminthiasis
Interventions: DRUG: Ivermectin|DRUG: Albendazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparative Study of Degarelix Three-month Depot in Three Different Dosing Regimens in Patients With Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: Degarelix|DRUG: Degarelix|DRUG: Degarelix
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Probiotic Effects on the Microbe-brain-gut Interaction and Brain Activity During Stress Tasks in Healthy Subjects
Status: COMPLETED
Conditions: Probiotics|Gut Microbiota|Emotional Stress|Magnetic Resonance Imaging
Interventions: DIETARY_SUPPLEMENT: Probiotic|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Instrument Assisted Soft Tissue Mobilization on Delayed Onset Muscle Soreness
Status: UNKNOWN
Conditions: Musculoskeletal Pain|Soreness, Muscle|Musculoskeletal Disorder
Interventions: OTHER: Instrument Assisted Soft Tissue Mobilization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of 8-week Supplementation With Black Chokeberry on Recovery in Highly Trained Rowers
Status: COMPLETED
Conditions: Inflammation;Muscle(S)|Oxidative Stress Injury|Permeability; Increased
Interventions: DRUG: black chokeberry (Aronia melanocarpa)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Tailored Care for Somatoform Vertigo/Dizziness
Status: UNKNOWN
Conditions: Somatoform Vertigo/Dizziness
Interventions: BEHAVIORAL: SVD-tailored Integrative Psychotherapy (IPT)|BEHAVIORAL: Self-help group (SHG)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Analysis to Detect Myometrial Cells in Peritoneal Washing in Patients Undergoing Minimally Invasive Hysterectomy Using Containment Bag at University of Texas Medical Branch
Status: RECRUITING
Conditions: Hysterectomy
Interventions: DIAGNOSTIC_TEST: Peritoneal washings
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Socket Preservation With BioHorizon's Striate+ Membrane and MinerOss X Plug
Status: NOT_YET_RECRUITING
Conditions: Socket Preservation
Interventions: DEVICE: MinerOss® X Plug|DEVICE: Striate+ Membrane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Talazoparib in Combination With Chemotherapy in Relapsed Pediatric AML to Determine Safety and Efficacy
Status: RECRUITING
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Talazoparib|DRUG: Topotecan|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CGM Treatment in Patients With Type 1 Diabetes Treated With Insulin Injections
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: DEVICE: Continuous glucose monitoring with DexCom G4 platina
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effect of Repeat Oral Dosing of GSK2118436 on Cardiac Repolarization in Subjects With V600 BRAF Mutation-Positive Tumors
Status: COMPLETED
Conditions: Cancer
Interventions: DRUG: GSK2118436 75 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of ACY-1215 Alone and in Combination With Bortezomib and Dexamethasone in Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: ACY-1215
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Increasing Digital Equity and Access Among Rural Patients (IDEA) Study
Status: COMPLETED
Conditions: Smoking Cessation
Interventions: BEHAVIORAL: Digital, evidence-based behavioral health program for smoking cessation|OTHER: Bluetooth enabled iPad|BEHAVIORAL: Coaching Support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study of Neoadjuvant Treatment With TQB2102 for Injection for Human Epidermal Growth Factor Receptor 2 (HER2) Positive Breast Cancer
Status: RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: 6.0 mg/kg of TQB2102 for injection|DRUG: 7.5 mg/kg of TQB2102 for injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Rituximab and Mycophenolate Mofetil (MMF) on Highly Sensitized Patients Awaiting Renal Transplant
Status: COMPLETED
Conditions: Kidney Failure, Chronic|Diabetic Nephropathies|Glomerulonephritis, IGA|Hypertension, Renal
Interventions: DRUG: Rituximab|DRUG: Mycophenolate mofetil (MMF)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ranibizumab Short- and Log-term Effects on Retinal Function in wAMD
Status: COMPLETED
Conditions: Age-Related Macular Degeneration|Retinal Function
Interventions: DRUG: Lucentis (Ranibizumab)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Manual Cervical Distraction: Measuring Chiropractic Delivery for Neck Pain Clinical Trial
Status: COMPLETED
Conditions: Neck Pain|Pain in Arm, Unspecified
Interventions: PROCEDURE: Manual Cervical Distraction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study Evaluating Long-term Safety and Efficacy of Lacosamide in Subjects With Painful Distal Diabetic Neuropathy.
Status: COMPLETED
Conditions: Painful Diabetic Neuropathy
Interventions: DRUG: Lacosamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Modification of the COVID-19 Vaccine Response by an Intervention on the Intestinal Flora
Status: ACTIVE_NOT_RECRUITING
Conditions: COVID-19|Vaccine Reaction|Elderly
Interventions: DIETARY_SUPPLEMENT: Taking capsule containing probiotics or placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Open Label Trial to Study the Long-term Safety and Efficacy of Seletracetam for the Treatment of Epilepsy
Status: WITHDRAWN
Conditions: Epilepsy
Interventions: DRUG: Seletracetam (ucb 44212)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Goal Directed Therapy for Patients Undergoing Major Vascular Surgery
Status: COMPLETED
Conditions: Abdominal Aortic Aneurysm Uncomplicated
Interventions: OTHER: Fluid titrated with the use of arterial pulse contour cardiac output monitor if SVV >13%|OTHER: Fluid titrated at the discretion of the attending anesthesiologist
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rituximab Treatment of Graves' Dysthyroid Ophthalmopathy
Status: COMPLETED
Conditions: Graves' Dysthyroid Ophthalmopathy|Thyroid Related Orbitopathy
Interventions: DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of School-Based Cognitive Behavioral Therapy in Preventing Depression in Young Adolescents
Status: COMPLETED
Conditions: Depression|Anxiety
Interventions: BEHAVIORAL: Adolescent only Penn Resiliency Program (Adolescent PRP)|BEHAVIORAL: Parent Penn Resiliency Program (Parent PRP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effects of Two Tear Substitutes in Patients With Dry Eye Syndrome
Status: COMPLETED
Conditions: Dry Eye|Tear Film|Lipid Layer|Liposic|Tears Naturale Forte
Interventions: DRUG: Liposic|DRUG: Tears Naturale Forte
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial of Single Dose Corifollitropin Alfa's Ability to Induce Multiple Follicular Growth During the First Week of Controlled Ovarian Stimulation for IVF or ICSI (38833)(P05788)
Status: COMPLETED
Conditions: In Vitro Fertilization
Interventions: DRUG: Org 36286 (corifollitropin alfa)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Analgesic Benefit of Adding the Blocks of the Intermediate and Medial Femoral Cutaneous Nerves in Addition to the Femoral Triangle Block for Postoperative Analgesia After a Knee Replacement Surgery
Status: RECRUITING
Conditions: Post-operative Pain|Anesthesia, Local
Interventions: PROCEDURE: Para-Sartorial Compartments (PACS) Block|PROCEDURE: Femoral Triangle Block (FTB)|PROCEDURE: Infiltration between popliteal artery and capsule of the knee (IPACK) block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Clinical and Radiographic Evaluation of Zinc Oxide-Propolis Mixture Versus Modified Triple Antibiotic Paste in LSTR
Status: NOT_YET_RECRUITING
Conditions: Pain, Postoperative|Periapical; Infection
Interventions: COMBINATION_PRODUCT: Zinc oxide propolis|COMBINATION_PRODUCT: Modified triple antibiotic paste
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CBT4CBT for Women in Residential Treatment for Substance Use Disorders
Status: COMPLETED
Conditions: Substance Use Disorders|Drug Abuse|Drug Addiction|Substance Abuse|Drug Use Disorders|Drug Dependence|Substance Addiction
Interventions: BEHAVIORAL: Treatment as Usual (TAU)|BEHAVIORAL: TAU+CBT4CBT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Doxorubicin Adsorbed to Magnetic Beads
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: MTC-DOX for Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Ability of Systane Ultra to Improve Subjective Symptoms of Ocular Irritation Post 60 Min. Athletic Performance.
Status: COMPLETED
Conditions: Dry Eye Symptoms|Visual Performance
Interventions: OTHER: Systane® Ultra
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Clinical Trial of YYC301 P3 for Treatment of Osteoarthritis of the Knee
Status: UNKNOWN
Conditions: Osteoarthritis, Knee
Interventions: DRUG: YYC301-1 & YYC301-2 & YYC301-3|DRUG: YYC301 placebo & Celecoxib 200mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Lower Limb Resistance Band Exercises in Phase 1 Cardiac Rehabilitation
Status: COMPLETED
Conditions: Cardiovascular Diseases
Interventions: OTHER: Lower Limb Resistance Band Exercises|OTHER: Routine Phase 1 cardiac rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: rTMS for Executive Function Deficits in Autism Spectrum Disorder
Status: COMPLETED
Conditions: Autism Spectrum Disorder
Interventions: DEVICE: Repetitive Transcranial Magnetic Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vosaroxin and Azacitidine in Treating Patients With Myelodysplastic Syndromes
Status: COMPLETED
Conditions: Myelodysplastic Syndromes
Interventions: DRUG: vosaroxin|DRUG: Azacitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endoscopic-vacuum Assisted Closure of Intrathoracic Postsurgical Leaks
Status: UNKNOWN
Conditions: Mediastinitis|Esophageal Neoplasms|Anastomotic Leakage
Interventions: PROCEDURE: Endoscopic vacuum assisted closure
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Machine Learning Ventilator Decision System VS. Standard Controlled Ventilation
Status: NOT_YET_RECRUITING
Conditions: Mechanical Ventilation|Critically Ill Patients
Interventions: DEVICE: Machine Learning Ventilator Decision System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Non-inferiority Study Comparing daVinci Skills Simulator to Mimic dV-Trainer for Preparing Residents to Perform Live Human Surgery
Status: TERMINATED
Conditions: Simulation for Preparation of Robotic Surgery
Interventions: OTHER: Mimic dv-Trainer|OTHER: daVinci Skills Simulator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: TENecteplase in Central Retinal Artery Occlusion Stuy (TenCRAOS)
Status: RECRUITING
Conditions: Central Retinal Artery Occlusion
Interventions: DRUG: Intravenous injection of Tenecteplase and one dose of placebo tablet|DRUG: One tablet of Acetylsalicylic Acid and one dose of IV placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: MEG Study of Mindfulness Based Stress Reduction
Status: COMPLETED
Conditions: Somatosensory Cortical Dynamics in Normal Humans
Interventions: BEHAVIORAL: Mindfulness Based Stress Reduction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Golimumab Versus Pamidronate for the Treatment of Axial Spondyloarthropathy: a 48-week Trial
Status: COMPLETED
Conditions: Spondyloarthropathy
Interventions: DRUG: golimumab|DRUG: Pamidronate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Carboplatin, Paclitaxel and Gemcitabine Hydrochloride With or Without Bevacizumab After Surgery in Treating Patients With Recurrent Ovarian, Epithelial, Primary Peritoneal, or Fallopian Tube Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Clear Cell Adenocarcinoma|Fallopian Tube Clear Cell Adenocarcinoma|Fallopian Tube Endometrioid Adenocarcinoma|Fallopian Tube Mucinous Adenocarcinoma|Fallopian Tube Serous Adenocarcinoma|Fallopian Tube Transitional Cell Carcinoma|Fallopian Tube Undifferentiated Carcinoma|Mucinous Adenocarcinoma|Ovarian Brenner Tumor|Ovarian Clear Cell Adenocarcinofibroma|Ovarian Clear Cell Adenocarcinoma|Ovarian Endometrioid Adenocarcinoma|Ovarian Seromucinous Carcinoma|Ovarian Serous Adenocarcinoma|Ovarian Transitional Cell Carcinoma|Ovarian Undifferentiated Carcinoma|Primary Peritoneal Clear Cell Adenocarcinoma|Primary Peritoneal Endometrioid Adenocarcinoma|Primary Peritoneal Serous Adenocarcinoma|Primary Peritoneal Transitional Cell Carcinoma|Primary Peritoneal Undifferentiated Carcinoma|Recurrent Fallopian Tube Carcinoma|Recurrent Ovarian Carcinoma|Recurrent Primary Peritoneal Carcinoma|Undifferentiated Carcinoma
Interventions: BIOLOGICAL: Bevacizumab|DRUG: Carboplatin|DRUG: Docetaxel|DRUG: Gemcitabine Hydrochloride|OTHER: Laboratory Biomarker Analysis|DRUG: Paclitaxel|OTHER: Quality-of-Life Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transauricular Vagus Nerve Stimulation Improves Postoperative Sleep Disorders in Elderly Patients.
Status: RECRUITING
Conditions: Vagus Nerve Stimulation
Interventions: DEVICE: Transauricular Vagal Nerve Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Nitrate Use to Obtain Radial Spasm Embarrassment (NURSE - TTS Trial)
Status: UNKNOWN
Conditions: Radial Artery Spasm
Interventions: DRUG: Transdermal glyceryl trinitrate 10mg patches|DRUG: Placebo patches
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Prospective Multi-centered Randomized Controlled Trial on Fruquintinib in Combination With HAIC in the Treatment of Liver Metastatic Colorectal Cancer After Failure of Second-line Systematic Therapy
Status: RECRUITING
Conditions: Colorectal Cancer
Interventions: DRUG: Fruquintinib|DRUG: HAIC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hormonal, Metabolic, and Signaling Interactions in PAH
Status: RECRUITING
Conditions: Idiopathic Pulmonary Arterial Hypertension|Heritable Pulmonary Arterial Hypertension|Scleroderma Associated Pulmonary Arterial Hypertension|Appetite Suppressant Associate PAH
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluating the Addition of the Immunotherapy Drug Atezolizumab to Standard Chemotherapy Treatment for Advanced or Metastatic Neuroendocrine Carcinomas That Originate Outside the Lung
Status: RECRUITING
Conditions: Advanced Extrapulmonary Neuroendocrine Carcinoma|Metastatic Extrapulmonary Neuroendocrine Carcinoma|Recurrent Extrapulmonary Neuroendocrine Carcinoma|Unresectable Extrapulmonary Neuroendocrine Carcinoma
Interventions: BIOLOGICAL: Atezolizumab|PROCEDURE: Biospecimen Collection|DRUG: Carboplatin|DRUG: Cisplatin|PROCEDURE: Computed Tomography|DRUG: Etoposide|PROCEDURE: Magnetic Resonance Imaging|OTHER: Patient Observation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Placebo-Controlled Crossover Trial With THC (Delta 9-Tetrahydrocannabinol) for the Treatment of Cramps in Amyotrophic Lateral Sclerosis (ALS)
Status: COMPLETED
Conditions: Cramps|Amyotrophic Lateral Sclerosis
Interventions: DRUG: Dronabinol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Enzastaurin in Chinese Patients With Advanced and/or Metastatic Solid Tumors or Lymphoma
Status: COMPLETED
Conditions: Solid Tumor|Lymphoma, Malignant
Interventions: DRUG: Enzastaurin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Influence of Preoperative Immunomodulation by Oral Impact on Postoperative Complications Following Cystectomies & Nephrectomies
Status: RECRUITING
Conditions: Urological Manifestations
Interventions: DIETARY_SUPPLEMENT: ORAL IMPACT treatment|OTHER: control
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effect of a Six Week Intensified Pharmacological Treatment for Major Depressive Disorder Compared to Treatment as Usual in Subjects Who Had a First-time Treatment Failure on Their First-line Treatment.
Status: RECRUITING
Conditions: Major Depressive Disorder|Treatment Resistant Depression
Interventions: DRUG: Esketamine Nasal Product|DRUG: Ketamine Hydrochloride|DRUG: Esketamine hydrochloride|DRUG: Second-line Antidepressants
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of a Nutritive Bar, in Reduction of Weight, Body Fat and Control of Appetite
Status: COMPLETED
Conditions: Overweight or Obesity
Interventions: DIETARY_SUPPLEMENT: Nutritional bar|BEHAVIORAL: Healthy Habits Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Daratumumab for First Line Treatment of Transplant-ineligible Myeloma Patients Followed by Daratumumab Re-treatment at First Relapse
Status: RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: Daratumumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Compare the Efficacy and Safety of Olaparib When Given in Combination With Carboplatin and Paclitaxel, Compared With Carboplatin and Paclitaxel in Patients With Advanced Ovarian Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Ovarian Cancer
Interventions: DRUG: olaparib|DRUG: paclitaxel|DRUG: carboplatin|DRUG: paclitaxel|DRUG: Drug: carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of VB4-845 Injection for Treating Patients With Non-muscle Invasive Bladder Cancer
Status: UNKNOWN
Conditions: Non-Muscle Invasive Bladder Cancer
Interventions: DRUG: VB4-845 Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: the Association Between Metabolic Syndrome and Its Components With Lupus Nephritis in Systemic Lupus Erythematosus Patients
Status: NOT_YET_RECRUITING
Conditions: Lupus Nephritis
Interventions: DIAGNOSTIC_TEST: lipid profile|DIAGNOSTIC_TEST: fasting blood suger
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p