pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Xeloda or UFT (Tegafur-uracil) With Folinic Acid in Advanced or Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: XELODA|DRUG: TEGAFUR URACIL - FOLINIC ACID
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low Dose Aspirin for Preterm Preeclampsia Preventionmg/Day Dose in High-risk Patients
Status: UNKNOWN
Conditions: Preeclampsia|Pregnancy Related
Interventions: DRUG: Aspirin 81Mg Ec Tab|DRUG: Aspirin 162Mg Ec Tab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Renal Physiology During Continuous Renal Replacement Therapy
Status: RECRUITING
Conditions: AKI|Continuous Renal Replacement Therapy|Dialysis|Intensive Care|Renal Blood Flow|Renal Failure|Blood Pressure
Interventions: OTHER: Starting at high or low blood pressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Pilot Study Evaluating the Impact of Stress Reduction on Atherosclerotic : Heart and Mind Study
Status: RECRUITING
Conditions: Atherosclerosis|Stress|Inflammation
Interventions: BEHAVIORAL: Stress Reduction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: PK/PD Study of Gan & Lee's Insulin Glargine Injection in Comparison to Lantus in Type 1 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: DRUG: Gan & Lee insulin glargine followed by Lantus|DRUG: Lantus followed by Gan & Lee insulin glargine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effects of Mesenchymal Stem Cell Secretome in Rheumatoid Arthritis Patients
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Messenchymal stem cell secretome|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Potential Drug-drug Interactions Between Gemfibrozil or Dabigatran Etexilate and Camlipixant
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Camlipixant + Gemfibrozil|DRUG: Dabigatran etexilate + camlipixant
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acupuncture in the Regulation of Dai Meridian for the Metabolism of Visceral Adipose Tissue in Abdominal Obese Patients
Status: COMPLETED
Conditions: Abdominal Obesity|Metabolic Syndrome
Interventions: OTHER: Acupuncture|OTHER: Healthy education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of the Eradication of Helicobacter Pylori and an Inhibitor of Pump With Proton Versus Control
Status: WITHDRAWN
Conditions: Positive Helicobacter Pylori Serology|Coronary Thrombosis|Supra-aortic Artery Thrombosis
Interventions: DRUG: during one week for the active treatments|DRUG: Pantoprazole|DRUG: Placebo Formula 515
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Intravesically Heated Thermo-chemotherapy With Mitomycin-C Prior to TURBT
Status: UNKNOWN
Conditions: Transitional Cell Carcinoma
Interventions: OTHER: BWT with Mitomycin-C prior TURBT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Donor Stem Cell Transplant in Treating Patients With Mantle Cell Lymphoma
Status: UNKNOWN
Conditions: Lymphoma
Interventions: BIOLOGICAL: alemtuzumab|BIOLOGICAL: donor lymphocytes|DRUG: carmustine|DRUG: cytarabine|DRUG: etoposide|DRUG: melphalan|PROCEDURE: allogeneic bone marrow transplantation|PROCEDURE: peripheral blood stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: M6620 Plus Standard Treatment in Oesophageal and Other Cancer
Status: COMPLETED
Conditions: Oesophageal Adenocarcinoma|Squamous Cell Carcinoma|Solid Tumor
Interventions: DRUG: M6620|DRUG: Cisplatin|DRUG: Capecitabine|RADIATION: Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Research & Evaluation of LumiraDx SARS-CoV-2 (COVID-19) Point of Care Ab Test
Status: ACTIVE_NOT_RECRUITING
Conditions: Covid19
Interventions: DIAGNOSTIC_TEST: Capillary Collection & Testing|DIAGNOSTIC_TEST: Venous Draw & Testing
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Allogeneic Stem Cell Transplantation (SCT) After Dose-reduced Conditioning for Myelofibrosis Patients
Status: COMPLETED
Conditions: Myelofibrosis
Interventions: PROCEDURE: Allogeneic Stem Cell Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Mouthwash Containing Camellia Sinensis Extracts on Oral Malodor
Status: COMPLETED
Conditions: Gingivitis|Halitosis
Interventions: DRUG: Camellia sinensis mouthwash|DRUG: Placebo mouthwash
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: AKT Inhibitor MK-2206 in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Adult Acute Megakaryoblastic Leukemia (M7)|Adult Acute Minimally Differentiated Myeloid Leukemia (M0)|Adult Acute Monoblastic Leukemia (M5a)|Adult Acute Monocytic Leukemia (M5b)|Adult Acute Myeloblastic Leukemia With Maturation (M2)|Adult Acute Myeloblastic Leukemia Without Maturation (M1)|Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities|Adult Acute Myeloid Leukemia With Del(5q)|Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)|Adult Acute Myeloid Leukemia With t(16;16)(p13;q22)|Adult Acute Myeloid Leukemia With t(8;21)(q22;q22)|Adult Acute Myelomonocytic Leukemia (M4)|Adult Erythroleukemia (M6a)|Adult Pure Erythroid Leukemia (M6b)|Recurrent Adult Acute Myeloid Leukemia
Interventions: DRUG: Akt inhibitor MK2206|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Autism Intervention Research Network for Behavioral Health (AIR-B II): Deployment Into Elementary Schools
Status: COMPLETED
Conditions: Autism
Interventions: BEHAVIORAL: Playground Intervention|BEHAVIORAL: STAT Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: VX-710, Doxorubicin, and Vincristine for the Treatment of Patients With Recurrent Small Cell Lung Cancer
Status: TERMINATED
Conditions: Lung Cancer
Interventions: DRUG: biricodar dicitrate|DRUG: doxorubicin hydrochloride|DRUG: vincristine sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pediatric Medication Therapy Management Trial
Status: RECRUITING
Conditions: Child, Only|Disabilities Multiple|Medication Interaction|Medication Compliance|Medication Administered in Error
Interventions: OTHER: Pediatric Medication Therapy Management (pMTM)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: TEOSYAL® RHA Ultra Deep and Perlane-L® for the Correction of Nasolabial Folds
Status: COMPLETED
Conditions: Nasolabial Folds, Wrinkles
Interventions: DEVICE: TEOSYAL® RHA Ultra Deep
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Gardening on Brain Activity
Status: COMPLETED
Conditions: Stress|Depression|Anxiety|Quality of Life
Interventions: OTHER: Gardening|PROCEDURE: Functional Magnetic Resonance Imaging (fMRI)|BEHAVIORAL: psychometric assessments
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Capecitabine Combined With Lenvatinib and Tislelizumab as Adjuvant Treatment After Resection in Patients With BTC
Status: RECRUITING
Conditions: Biliary Tract Cancer
Interventions: DRUG: Capecitabine combined with lenvatinib and tislelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Kaiser Permanente VACCination Improvement With Nudge-based CardiovAscular Targeted Engagement
Status: NOT_YET_RECRUITING
Conditions: Cardiovascular Diseases|Influenza|Behavior, Social
Interventions: BEHAVIORAL: Cardiovascular-Focused Nudge Communication
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Comparison of Short-term Application of Dialysis Catheter With Tunnel-cuffed Catheter Versus Non-ccuffed Catheter: a Multicenter Prospective Cohort Study
Status: RECRUITING
Conditions: Clarify the Difference of Short-term Infection Rate Between Diffrent Catheter
Interventions: PROCEDURE: Tunnel-cuffed Catheter|PROCEDURE: Non-ccuffed Catheter
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study to Evaluate the Efficacy of SDP-4 in Subjects With Dry Eye Disease (DED) (SDP-4-CS202)
Status: COMPLETED
Conditions: Dry Eye
Interventions: DRUG: Vehicle|DRUG: SDP-4 Ophthalmic Solution (1.0%)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: RIGENERA 2.0 Trial
Status: WITHDRAWN
Conditions: Anterior Myocardial Infarction|Heart Failure
Interventions: DRUG: rhu G-CSF|DRUG: optimal standard of care|PROCEDURE: Myocardial Contrast Echocardiography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cardioprotective Effects of Green Tea Versus Maté Intake
Status: UNKNOWN
Conditions: Dyslipidemia|Inflammation|Obesity
Interventions: DIETARY_SUPPLEMENT: Yerba Mate Tea|DIETARY_SUPPLEMENT: Green tea|DIETARY_SUPPLEMENT: Apple tea
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility and Impact of a Decision Rule for Imaging of Emergency Department Patients With Suspected Kidney Stone
Status: COMPLETED
Conditions: Kidney Stones
Interventions: RADIATION: Ultra low dose CT scan|RADIATION: Regular CT or Low Dose CT scan|RADIATION: No imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Radiation Therapy and Capecitabine With or Without Oxaliplatin in Treating Patients Who Are Undergoing Surgery for Stage II or Stage III Rectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: capecitabine|DRUG: oxaliplatin|PROCEDURE: conventional surgery|PROCEDURE: neoadjuvant therapy|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Skin Protectant Textile Efficacy Study for Managing Skin Fold Conditions
Status: ENROLLING_BY_INVITATION
Conditions: Erythema|Maceration|Lesion Skin|Skin Folds
Interventions: DEVICE: DriGo Skin Protectant Textile
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Ixazomib Citrate With Gemcitabine Hydrochloride and Doxorubicin Hydrochloride in Treating Patients With Urothelial Cancer That is Metastatic or Cannot Be Removed by Surgery
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Urothelial Carcinoma|Transitional Cell Carcinoma|Unresectable Transitional Cell Carcinoma
Interventions: DRUG: Doxorubicin Hydrochloride|DRUG: Gemcitabine Hydrochloride|DRUG: Ixazomib Citrate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HIV Reservoir Dynamics After Switching to Dolutegravir in Patients on a PI and 2 NRTI Based Regimen
Status: COMPLETED
Conditions: HIV-1
Interventions: DRUG: Dolutegravir|DRUG: PI|DRUG: 2 NRTI|DRUG: 2 NRTI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Specific Anti Factor Xa Activity Dosage to Enhance Detection of Nonadherence in Atrial Fibrillation Patients
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: BEHAVIORAL: Adherence to oral anticoagulant treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Evaluation of the Effect of Leukocyte and Platelet-rich Fibrin on Healing After Periradicular Surgery
Status: ACTIVE_NOT_RECRUITING
Conditions: Apical Periodontitis|Periapical Lesion
Interventions: OTHER: Retrograde Filling Group|OTHER: Retrograde Filling+L-PRF Group|OTHER: (Orthograde Filling Group / OG Group).|OTHER: (Orthograde Filling+L-PRF Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Efficacy and Safety of Darunavir/Cobicistat/Emtricitabine/Tenofovir Alafenamide (D/C/F/TAF) Fixed Dose Combination (FDC) Versus a Regimen Consisting of Darunavir/Cobicistat FDC With Emtricitabine/Tenofovir Disoproxil Fumarate FDC in Treatment-naive HIV Type 1 Infected Subjects
Status: COMPLETED
Conditions: Immunodeficiency Virus Type 1, Human
Interventions: DRUG: Darunavir/Cobicistat/Emtricitabine/Tenofovir Alafenamide FDC|DRUG: DRV/COBI FDC|DRUG: FTC/TDF FDC|DRUG: D/C/F/TAF FDC - Matching Placebo|DRUG: FTC/TDF FDC Matching Placebo|DRUG: DRV/COBI FDC Matching Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Mosapride on Recovery of Intestinal Motility After Elective Colorectal Cancer Surgery
Status: UNKNOWN
Conditions: Colorectal Cancer|Bowel Ileus
Interventions: DRUG: Mosapride|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Scoreflex NC - Scoring PTCA Catheter
Status: COMPLETED
Conditions: Coronary Artery Disease|Coronary Disease|Myocardial Ischemia|Heart Diseases|Arteriosclerosis|Cardiovascular Diseases
Interventions: DEVICE: Scoreflex NC Scoring PTCA catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasound for the Detection of Oxaliplatin-Induced Peripheral Neuropathy
Status: RECRUITING
Conditions: Gastrointestinal Cancer|Colorectal Cancer
Interventions: DIAGNOSTIC_TEST: Ultrasound - Serial and Tibial Nerve|PROCEDURE: Skin Biopsy|OTHER: Abbreviated Neurologic Exam|OTHER: Blood draw|DIAGNOSTIC_TEST: Nerve Conduction Study|OTHER: QLQ-CIPN20 Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Role of Psychoanalysis in Prevention of Girl Child Maltreatment and Neglect
Status: COMPLETED
Conditions: Abuse Neglect|Social; Deprivation, Maltreatment Syndrome (Infant or Child)
Interventions: BEHAVIORAL: Psychoanalytic therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation in Practice of the Impact of NIrsevimab on EmeRgency Use for BRONCHIOlitis
Status: COMPLETED
Conditions: Bronchiolitis|Respiratory Syncytial Virus (RSV)|Immunization; Infection
Interventions: OTHER: No intervention. Observational retrospective study
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety Study of an Oral Vaccine to Prevent Avian Influenza
Status: COMPLETED
Conditions: Avian Influenza|Bird Flu
Interventions: BIOLOGICAL: ND1.1|BIOLOGICAL: Placebo control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Radical Gastrectomy With/Without HIPEC in Advanced Gastric Cancer Patients
Status: UNKNOWN
Conditions: Malignant Neoplasm of Stomach
Interventions: PROCEDURE: intraperitoneal chemoperfusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of SGT-53 in Children With Refractory or Recurrent Solid Tumors
Status: SUSPENDED
Conditions: Neoplasm
Interventions: GENETIC: SGT-53|DRUG: Topotecan|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Yunnan Baiyao in Improving Fracture Pain
Status: NOT_YET_RECRUITING
Conditions: Distal Radius Fracture
Interventions: DRUG: Yunnan Baiyao|DRUG: Celecoxib 200mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Trial of Epcoritamab in Combination With Rituximab-mini CVP for Older Unfit/Frail Patients or Anthracycline-Ineligible Adult Patients With Newly Diagnosed Diffuse Large B-cell Lymphoma
Status: RECRUITING
Conditions: Large B-cell Lymphoma
Interventions: DRUG: Prednisone|DRUG: Rituximab|DRUG: Cyclophosphamide|DRUG: Vincristine|DRUG: Epcoritamab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of Prucalopride to Treat Chronic Intestinal Pseudo-Obstruction (CIP)
Status: COMPLETED
Conditions: Chronic Intestinal Pseudo-Obstruction
Interventions: DRUG: PRU-PLA-PRU-PLA|DRUG: PLA-PRU-PLA-PRU|DRUG: PLA-PRU-PRU-PLA|DRUG: PRU-PLA-PLA-PRU
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose:
Clinical trial: Responses of Myocardial Ischemia to Escitalopram Treatment
Status: COMPLETED
Conditions: Myocardial Ischemia
Interventions: DRUG: Escitalopram|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of BTDS (Buprenorphine Transdermal System) and Placebo in Low Back Pain
Status: COMPLETED
Conditions: Low Back Pain
Interventions: DRUG: Placebo|DRUG: Buprenorphine Transdermal System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pregabalin Stabilize Cardiovascular Response to Intubation
Status: COMPLETED
Conditions: Effect of Laryngoscopy and Tracheal Intubation
Interventions: DRUG: Pregabalin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Resveratrol on Endothelial Function in Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: DIETARY_SUPPLEMENT: Resveratrol|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Comparison of the Benefits of Mindfulness Based Cognitive Therapy, Relaxation Therapy and a Waiting List Control in the Management of Distress in Chronic Tinnitus Patients
Status: COMPLETED
Conditions: Tinnitus
Interventions: OTHER: No treatment waiting period|BEHAVIORAL: Mindfulness Based Cognitive Therapy|BEHAVIORAL: Relaxation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Two Techniques of Capsulotomy During Capsulorrhaphy in Cases of Developmental Dysplasia of the Hip
Status: ENROLLING_BY_INVITATION
Conditions: Developmental Dysplasia of the Hip
Interventions: PROCEDURE: U shaped capsular incision during capsulorrhaphy|PROCEDURE: T-shaped capsular incision diuring capsulorraphy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Medical Therapies in Marfan Syndrome.
Status: COMPLETED
Conditions: Marfan Syndrome
Interventions: DRUG: Atenolol|DRUG: VERAPAMIL|DRUG: Perindopril
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Double-Blind, Randomized Control Trial Comparing Botulinum Toxin Type A (Botox) and Placebo in the Treatment of Idiopathic Clubfoot
Status: COMPLETED
Conditions: Idiopathic Clubfoot (Talipes Equinovarus)
Interventions: DRUG: Botox
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Teacher Training and the Introduction of Early Adjustments on the Developmental Trajectory of Children at Risk of SLLD in Pre-school.
Status: ACTIVE_NOT_RECRUITING
Conditions: Language Disorders in Children|Learning; Developmental Disorder
Interventions: BEHAVIORAL: Teacher training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effects of Concurrent HIIT and WB-EMS Exercise on the Cardiometabolic Risk Profile in Obese Individuals
Status: UNKNOWN
Conditions: Overweight and Obesity|Metabolic Syndrome
Interventions: OTHER: HIIT + WB-EMS|OTHER: WB-EMS + HIIT|OTHER: HIIT + CST|OTHER: CST + HIIT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Relative Bioavailability Study of Propranolol HCl 160 mg Tablets Under Non-fasting Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Propranolol Hydrochloride Extended Release Capsules 160 mg|DRUG: INDERAL® LA 160 mg Capsules, single dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Effect of 4 Weeks of Citrulline and Glutathione Supplementation on Arterial Function
Status: COMPLETED
Conditions: Menopause|Cardiovascular Risk Factor
Interventions: DIETARY_SUPPLEMENT: L-Citrulline|DIETARY_SUPPLEMENT: L-Citrulline|DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: Glutathione
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Application of Electrically Driven Atomized Surface Anesthesia in ATI in Patients With Predictably Difficult Airway.
Status: COMPLETED
Conditions: Anesthesia, Endotracheal
Interventions: OTHER: atomizer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Familial Fecal Microbiota Transplant for the Treatment of Subjects With Autism Spectrum Disorders
Status: NOT_YET_RECRUITING
Conditions: Autism|Autism Spectrum Disorder
Interventions: BIOLOGICAL: Fecal Microbiota Transplant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Prospective Randomized Study of Medial Patellofemoral Ligament (MPFL) Reconstruction
Status: TERMINATED
Conditions: Patella-Dislocation|Patellofemoral Osteoarthritis|Patellar Instability
Interventions: PROCEDURE: Patellofemoral stabilizing surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Changes in Weight, Body Composition and Metabolic Parameters After Discontinuing Dolutegravir or Tenofovir Disproxil
Status: UNKNOWN
Conditions: Hiv|HIV Infections|HIV Lipodystrophy|Osteoporosis|Renal Insufficiency|Weight Gain|Obesity
Interventions: DRUG: Dolutegravir/Lamivudine 50 MG-300 MG Oral Tablet [DOVATO]|DRUG: Doravirine/Lamivudine/Tenofovir Disoproxil Fumarate 100 MG-300 MG-300 MG Oral Tablet [DELSTRIGO]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy in Reducing Fractures and Safety of Zoledronic Acid in Men With Osteoporosis
Status: COMPLETED
Conditions: Male Osteoporosis
Interventions: DRUG: Zoledronic acid 5 mg iv|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cerebral Blood Perfusion Changes After General Anesthesia for Craniotomy
Status: COMPLETED
Conditions: Brain Neoplasms|Surgery|Hyperemia
Interventions: DEVICE: Transcranial Doppler (TCD)|PROCEDURE: jugular venous bulb catheterization|PROCEDURE: Tumor removal surgery under general anesthesia|PROCEDURE: Radial artery catheterization|PROCEDURE: Abdominal surgery under general anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Clinical Study of Wrist Blood Pressure Monitor in Conformance With the ANSI/AAMI SP10 Standard
Status: COMPLETED
Conditions: Efficacy of Wrist BPM Measurement|Hypertension
Interventions: DEVICE: Blood pressure Transtek Wrist Blood Pressure Monitor, TMB-1117|DEVICE: Blood pressure Reference Device: Yuyue Medical Blood Pressure Meter, YYBP-2
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A 6 Month Safety and Efficacy Study of Once Daily Ciclesonide Hydrofluoroalkane (HFA) in the Treatment of Perennial Allergic Rhinitis (PAR) in Subjects 12 Years and Older
Status: COMPLETED
Conditions: Allergic Rhinitis|Perennial Allergic Rhinitis
Interventions: DRUG: Ciclesonide HFA 80 mcg|DRUG: Ciclesonide HFA 160 mcg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare Eribulin Mesylate + Pertuzumab + Trastuzumab With Paclitaxel or Docetaxel + Pertuzumab + Trastuzumab
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: DRUG: Pertuzumab|DRUG: Trastuzumab|DRUG: Docetaxel|DRUG: Paclitaxel|DRUG: Eribulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimizing Transcranial Direct Current Stimulation for Motor Recovery From Hemiparesis
Status: COMPLETED
Conditions: Stroke|Cerebrovascular Accident
Interventions: DEVICE: Neuroconn Eldith stimulator by Magstim
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Epidural Analgesia and Troubles of Fetal Cardiaq Rythm : Effect of the Systemic Transfer of Ropivacaine and Sufentanil
Status: COMPLETED
Conditions: Fetal Cardiac Rhythm Abnormalities
Interventions: DRUG: ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Maintenance Vitamin D Therapy for Secondary Hyperparathyroidism (2HPT)
Status: COMPLETED
Conditions: Secondary Hyperparathyroidism
Interventions: DRUG: 1.0 μg/day Alfacalcidol|DRUG: 0.25 μg/day Alfacalcidol
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Maternal Buprenorphine-naloxone Treatment and the Infant
Status: COMPLETED
Conditions: Maternal Opioid Use Disorder|Opioid Exposed Infant
Interventions: DEVICE: fetal monitoring|DRUG: Buprenorphine Naloxone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Chemotherapy and Radiation Therapy With or Without Metformin Hydrochloride in Treating Patients With Stage III Non-small Cell Lung Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Adenosquamous Lung Carcinoma|Bronchioloalveolar Carcinoma|Large Cell Lung Carcinoma|Lung Adenocarcinoma|Non-Small Cell Lung Carcinoma|Recurrent Non-Small Cell Lung Carcinoma|Squamous Cell Lung Carcinoma|Stage IIIA Non-Small Cell Lung Cancer|Stage IIIB Non-Small Cell Lung Cancer
Interventions: RADIATION: Radiation Therapy|DRUG: Carboplatin|DRUG: Metformin|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preoperational Fine Needle Aspiration of Pathological Parathyroid Gland
Status: WITHDRAWN
Conditions: Parathyroid Adenoma|Hypercalcemia
Interventions: DIAGNOSTIC_TEST: pre operative parathyroid hormone level measurement|DIAGNOSTIC_TEST: pre operative parathyroid cytology|DIAGNOSTIC_TEST: parathyroid hormone level measurement|DIAGNOSTIC_TEST: parathyroid cytology
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: MAD Study to Evaluate the Safety, Tolerability and Pharmacokinetics of Intravenous Zidebactam in Healthy Adults
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: 3 g or 6 g Zidebactam|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Safety, Ultrasound Conspicuity, and Migration of Twinkling Markers in Patients With Locally Advanced Breast Cancer
Status: ENROLLING_BY_INVITATION
Conditions: Anatomic Stage III Breast Cancer AJCC v8|Locally Advanced Breast Carcinoma|Resectable Breast Carcinoma
Interventions: PROCEDURE: Magnetic Resonance Imaging|PROCEDURE: Mammogram|PROCEDURE: Ultrasound|PROCEDURE: Ultrasound-Guided Biopsy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: MLC1501 Study Assessing Efficacy in Post STrOke Subjects With mOtor Deficits
Status: RECRUITING
Conditions: Stroke|Stroke, Ischemic|Strokes Thrombotic|Stroke Sequelae|Stroke, Cardiovascular|Stroke, Embolic|Stroke, Cryptogenic
Interventions: OTHER: Placebo|DRUG: MLC1501
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intraoperative Manual Correction of Iliosacral Displacement of the Sacroiliac Joint in Total Hip Arthroplasty
Status: UNKNOWN
Conditions: Total Hip Arthroplasty
Interventions: PROCEDURE: Total Hip Arthroplasty|PROCEDURE: Manual correction of the sacroiliac joint
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect Of I-Gel And Ambu Aura-I Use On Laryngofaryngeal Mucosa
Status: UNKNOWN
Conditions: Mucosal Damage
Interventions: DEVICE: I-gel|DEVICE: Ambu aura i
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SCREENING
Clinical trial: (S5-SAMU) Randomized Study Comparing the ASV (Adaptative Support Ventilation) to Conventional Ventilation
Status: TERMINATED
Conditions: Respiratory Distress Syndrome
Interventions: DEVICE: Hamilton T1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Long-term Efficacy and Safety Study With Oralgen Grass Pollen
Status: COMPLETED
Conditions: Allergic Rhinoconjunctivitis
Interventions: DRUG: Oralgen|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Vitamin B on Plasma Neurofilament Light Protein (NFL) in HIV-infected Individuals With Increased Plasma Homocysteine
Status: UNKNOWN
Conditions: HIV
Interventions: DRUG: Cyanocobalamin|DRUG: Folate|DRUG: Pyridoxine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Identifying and Treating Depression in the Orthopaedic Trauma Population
Status: NOT_YET_RECRUITING
Conditions: Depression
Interventions: DRUG: Fluoxetine 20 MG|DRUG: Duloxetine 30 MG|OTHER: Observation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intra- and Interrater Reliability of Quantitative Ultrasound Assessment of Gastric Content in Term Parturients Before Elective Caesarean Delivery
Status: COMPLETED
Conditions: Pregnancy|Respiratory Aspiration of Gastric Content
Interventions: DEVICE: Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of PF-00299804 When Given Through a Feeding Tube in Locally Advanced Head and Neck Squamous Cell Carcinoma
Status: COMPLETED
Conditions: Head and Neck Squamous Cell Carcinoma
Interventions: DRUG: PF-00299804
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparison of the Clinical Success of Pediatric Zirconia Crowns Applied With Different Luting Cements
Status: COMPLETED
Conditions: Dental Caries|Dental Plaque|Dental Caries in Children
Interventions: PROCEDURE: Tooth Preperation|PROCEDURE: Cementation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Casting and Splinting in Pediatric Radial Buckle Fractures
Status: COMPLETED
Conditions: Distal Radial Buckle Fractures
Interventions: PROCEDURE: Volar Splint|PROCEDURE: Cast
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety of Sanofi Pasteur's CYD Dengue Vaccine in Healthy Children and Adolescents in Latin America
Status: COMPLETED
Conditions: Dengue|Dengue Hemorrhagic Fever|Dengue Virus|Dengue Fever
Interventions: BIOLOGICAL: CYD Dengue Vaccine|BIOLOGICAL: Tetanus Toxoid Reduced Diphtheria Toxoid Acellular Pertussis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: 7-Keto DHEA for the Treatment of PTSD
Status: COMPLETED
Conditions: PTSD
Interventions: DRUG: 7-Keto Dehydroepiandrosterone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Worldwide Trends on COVID-19 Research After the Declaration of COVID-19 Pandemic
Status: UNKNOWN
Conditions: COVID-19
Interventions: DRUG: Convalescent Plasma Transfusion|DRUG: Hydroxychloroquine|DRUG: DAS181|DRUG: Ivermectin|DRUG: Interferon Beta-1A
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Herniorrhaphy for Postoperative Pain
Status: RECRUITING
Conditions: Hernia, Inguinal
Interventions: DRUG: local anaesthetic injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of MRG002 in the Treatment of HER2-positive/HER2-low Locally Advanced or Metastatic Gastric/Gastroesophageal Junction Cancer.
Status: UNKNOWN
Conditions: Locally Advanced Gastric Cancer|Metastatic HER2 Positive Gastroesophageal Junction Cancer
Interventions: DRUG: MRG002
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Efficacy, Safety, Tolerability and Immunogenicity of 100µg NIC002 Vaccine in Cigarette Smokers Who Are Motivated to Quit Smoking.
Status: COMPLETED
Conditions: Smokers
Interventions: BIOLOGICAL: NIC002|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immunotherapy With CD19 CAR γδT-cells for B-Cell Lymphoma, ALL and CLL
Status: UNKNOWN
Conditions: Leukemia|Lymphoma
Interventions: BIOLOGICAL: Anti-CD19-CAR γδT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acceptability of a Cereal for Complementary Feeding of Infants and Young Children Made From Caterpillars
Status: COMPLETED
Conditions: Malnutrition|Stunting of Growth
Interventions: DIETARY_SUPPLEMENT: caterpillar cereal
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Multi Doses Study to Compare the Pharmacokinetics of BR9003A and BR9003 in Healthy Adult Subjects
Status: COMPLETED
Conditions: Smoking Cessation
Interventions: DRUG: BR9003 2mg|DRUG: BR9003A 1mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Effects of TT With and Without Visual and Auditory Cues for Freezing & Gait Patients With PD
Status: RECRUITING
Conditions: Parkinson Disease
Interventions: DIAGNOSTIC_TEST: Treadmill Training With Visual and Auditory Cues|DIAGNOSTIC_TEST: Treadmill Training Without Visual and Auditory Cues
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Amplatzer Amulet LAAO vs. NOAC
Status: RECRUITING
Conditions: Atrial Fibrillation|Stroke|Bleeding
Interventions: DEVICE: Left Atrial Appendage Occlusion (Amplatzer Amulet LAA Occluder)|DRUG: Non-Vitamin K Oral Antagonists
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transcranial Magnetic Stimulation for Epilepsy
Status: TERMINATED
Conditions: Epilepsy
Interventions: DEVICE: Transcranial magnetic stimulation - Placebo Arm|DEVICE: Transcranial magnetic stimulation - Active Arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Off-the-shelf CD123 CAR-NK for R/R AML
Status: RECRUITING
Conditions: Acute Myeloid Leukemia, in Relapse|Acute Myeloid Leukemia Refractory
Interventions: DRUG: JD123 injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Analysis of the Symptomatic Domains Most Relevant to Charcot Marie Tooth Neuropathy (CMT) Patients
Status: COMPLETED
Conditions: Charcot Marie Tooth Disease (CMT)|Hereditary Sensory and Motor Neuropathy|Nerve Compression Syndromes|Tooth Diseases|Congenital Abnormalities|Genetic Diseases, Inborn|Heredodegenerative Disorders, Nervous System
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Mediastinal Staging of Lung Cancer With EBUS-TBNA and EUS-B-FNA
Status: COMPLETED
Conditions: Lung Cancer
Interventions: PROCEDURE: EBUS-TBNA, EUS-B-FNA (EUS-FNA with bronchoscope)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Acceptance and Commitment Therapy for Patients With Multi-organ Bodily Distress Syndrome (Stress-4)
Status: COMPLETED
Conditions: Somatisation Disorder|Somatoform Disorders
Interventions: BEHAVIORAL: Acceptance and Commitment Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Randomised Controlled Trial of Intervention for Children and Young People Experiencing Family Substance Use
Status: NOT_YET_RECRUITING
Conditions: Wellness, Psychological
Interventions: BEHAVIORAL: A story based intervention called 'The Shadow of Tallystick Valley'
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy and Safety of NNC 0078-0000-0007 in Patients With Congenital Haemophilia and Inhibitors
Status: COMPLETED
Conditions: Congenital Bleeding Disorder|Haemophilia A With Inhibitors|Haemophilia B With Inhibitors
Interventions: DRUG: vatreptacog alfa (activated)|DRUG: eptacog alfa (activated)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cardiac Flow Measurements in Pregnant Women by Non Invasive Techniques
Status: RECRUITING
Conditions: Pregnancy Related|Cardiac Output
Interventions: DEVICE: trans thoracic echocardiography measure|DEVICE: ICON measure|DEVICE: USCOM
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Sensing Oxygen Saturations Using Abdominal NIRS With an Investigational Realtime Device (Songbird)
Status: NOT_YET_RECRUITING
Conditions: NEC
Interventions: DIAGNOSTIC_TEST: NIRS
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Venetoclax and Obinutuzumab for Relapsed/Refractory Primary CNS Lymphoma
Status: TERMINATED
Conditions: Primary CNS Lymphoma
Interventions: DRUG: Venetoclax|DRUG: Obinutuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Repeated Analgesia With Kangaroo Care
Status: COMPLETED
Conditions: Pain|Development
Interventions: BEHAVIORAL: Kangaroo Mother Care|DIETARY_SUPPLEMENT: Sucrose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Use of Interactive Binocular Treatment (I-BiT) for the Management of Anisometropic, Strabismic and Mixed Amblyopia in Children Aged 3.5 - 12 Years
Status: UNKNOWN
Conditions: Amblyopia|Strabismus
Interventions: DEVICE: I-Bit plus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Intravenous Tissue-type Plasminogen Activator on Acute Ischemic Stroke Patients With Large Vessel Occlusions
Status: UNKNOWN
Conditions: Stroke, Ischemic|Stroke, Acute
Interventions: DRUG: Plasminogen Activators
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Umbilical Cord Mesenchymal Stem Cell Treatment for Crohn's Disease
Status: COMPLETED
Conditions: Crohn Disease
Interventions: OTHER: UC-MSCs by peripheral intravenous infusion|DRUG: received hormone maintenance therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Combined Kendell and McKenzie on Brachial Plexus Mechanosensitivity in Chronic Non-Specific Neck Pain
Status: COMPLETED
Conditions: Chronic Non-Specific Neck Pain
Interventions: OTHER: combined Kendell and McKenzie cervical posture correction exercises, ultrasound, hot packs, cervical extensors stretching and strengthening exercise.|OTHER: ultrasound, hot packs, cervical extensors stretching and strengthening exercise.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Spinal Cord Stimulation in Patients With a Failed Back Surgery Syndrome.
Status: UNKNOWN
Conditions: Back Pain|Spinal Cord Stimulation
Interventions: DEVICE: Spinal cord stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Phase 2 Study to Evaluate PVX-410 + Pembrolizumab + Chemotherapy for Metastatic, PD-L1+ Triple-Negative Breast Cancer
Status: NOT_YET_RECRUITING
Conditions: Metastatic Triple-Negative Breast Carcinoma
Interventions: DRUG: PVX-410
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ANTIVIRAL TREATMENT OF CYTOMEGALOVIRUS IN DEPRESSION
Status: RECRUITING
Conditions: Major Depressive Disorder
Interventions: DRUG: Valganciclovir|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety of Cultured Allogeneic Adult Umbilical Cord Derived Mesenchymal Stem Cell Intravenous Infusion for IBD
Status: RECRUITING
Conditions: Inflammatory Bowel Diseases
Interventions: BIOLOGICAL: AlloRx
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT