pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Ulcerative Colitis and Vitamin D Supplementation
Status: WITHDRAWN
Conditions: Ulcerative Colitis
Interventions: DRUG: Vitamin D|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Primary Subtalar Arthrodesis for Calcaneal Fractures
Status: NOT_YET_RECRUITING
Conditions: Calcaneus Fracture
Interventions: PROCEDURE: Primary Fusion (Open Reduction Internal Fixation (ORIF) + Primary Subtalar Arthrodesis (PSTA)|PROCEDURE: Open Reduction Internal Fixation (ORIF) only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anti-CD19/CD22 Bispecific Chimeric Antigen Receptor（CAR)-T Cell Therapy for Measurable Residual Disease(MRD) Positive ALL
Status: COMPLETED
Conditions: MRD-positive|Acute Lymphoblastic Leukemia
Interventions: BIOLOGICAL: anti-CD19/CD22 CAR-T cells|DRUG: Fludarabine|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Platelet Rich Plasma Injection Versus Surgical and Medical Treatment of Mild-moderate Carpel Tunnel Syndrome.
Status: UNKNOWN
Conditions: Carpal Tunnel
Interventions: DRUG: 30 patients received conventional medical treatment (NSAIDs, diclofenac 150 mg/day for 2 weeks and 1500 g vitamin B 12 per day for 6 weeks) and hand support.|PROCEDURE: 30 patients went to surgical procedure|OTHER: Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Intermittent Pneumatic Compression Device of Lower Limbs in Oligohydramnios
Status: UNKNOWN
Conditions: Oligohydramnios|Amniotic Fluid; Disorder
Interventions: DEVICE: intermittent pneumatic pressure device (Kendall SCD™ 700 Smart Compression™ System)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Message Communicating Latest Data on COVID-19 Transmission in Patient's Area
Status: COMPLETED
Conditions: COVID-19
Interventions: BEHAVIORAL: COVID Booster text messages
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Low Dose Ticagrelor Versus Low Dose Prasugrel in Patients With Prior Myocardial Infarction
Status: COMPLETED
Conditions: Myocardial Infarction|Diabetes Mellitus|Coronary Artery Disease|Renal Disease
Interventions: DRUG: Ticagrelor 60 mg|DRUG: Prasugrel 5mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ODYSSEY: A Study to Investigate the Efficacy of Tradipitant in Treating Severe or Critical COVID-19 Infection
Status: ENROLLING_BY_INVITATION
Conditions: Coronavirus Infection
Interventions: DRUG: Tradipitant|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Graves´Ophthalmopathy With Simvastatin (GO-S)
Status: RECRUITING
Conditions: Graves Ophthalmopathy|Thyroid Associated Ophthalmopathy|Thyroid Associated Orbitopathy
Interventions: DRUG: Simvastatin 40mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Inflammatory Cytokine Levels Between Single-port and Three-port Thoracoscopic Lobectomy in the Treatment of Non-small Cell Lung Cancersurgery on Perioperative Clinical Indexes、Inflammatory Reaction and Quality of Life Scores of Patients With Non-small Cell Lung Cancer
Status: COMPLETED
Conditions: Video-assisted Thoracoscopic Surgery|Inflammatory Reaction|Life Scores
Interventions: OTHER: uni-portal VATS group|OTHER: three port VATS group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transform Type 2: Examining Meal-Delivery and Education for Diabetes Self-Care
Status: COMPLETED
Conditions: PreDiabetes|Diabetes Mellitus, Type 2
Interventions: BEHAVIORAL: Education|BEHAVIORAL: Meal delivery|BEHAVIORAL: Lifestyle coaching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Subconjunctival Atropine and Intracameral Epinephrine for Pupil Dilation in Phacoemulsification
Status: UNKNOWN
Conditions: Cataract|Mydriasis|Adverse Drug Event
Interventions: DRUG: Atropine sulfate and epinephrine|DRUG: Topical cyclopentolate and phenylephrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Comparison of Krill and Fish Oil on Clinical and Biochemical Outcomes in Depression
Status: COMPLETED
Conditions: Depression
Interventions: DIETARY_SUPPLEMENT: Krill and Fish Oil vs. Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Body Constitution Classification Based Comprehensive Health Management Intervention on Obese Population
Status: COMPLETED
Conditions: Overweight|Obesity
Interventions: BEHAVIORAL: Health Management|BEHAVIORAL: General Management|OTHER: Placebo|DIETARY_SUPPLEMENT: SCHSANDRA PLUS, YI RUI CAPSULE, Gest Aid Plus: INFINITUS®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Transcranial Direct Current Stimulation in Patients With Disorders of Consciousness
Status: COMPLETED
Conditions: Vegetative State|Minimally Conscious State|Disorders of Consciousness
Interventions: DEVICE: Anodal tDCS|DEVICE: sham tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cardiac Strains for Optimization of CRT in Non-Responders
Status: COMPLETED
Conditions: Chronic Heart Failure
Interventions: DEVICE: CRT-D re-programming|DIAGNOSTIC_TEST: Trans-Thoracic Echocardiography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Whole Blood Transcriptomic Signal According to Coronary Atherosclerotic Plaque Burden Assessed by CT Angiography
Status: ENROLLING_BY_INVITATION
Conditions: Calcific Coronary Arteriosclerosis|Coronary Stenosis|Coronary Plaque|Aortic Calcification|Atherosclerotic Plaque
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Proof of Concept Study for Safety and Efficacy of EDP239 in Hepatitis C Subjects
Status: COMPLETED
Conditions: Hepatitis C
Interventions: DRUG: EDP239|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Visual Inspection With Acetic Acid Compared to Lugol's Iodine in HIV-infected Women
Status: COMPLETED
Conditions: Cervical Intraepithelial Neoplasia|Cervical Cancer|HIV
Interventions: PROCEDURE: Visual Inspection with Acetic Acid|PROCEDURE: Visual Inspection with Lugol's Iodine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effects of Muscle Vibration on the Development of Spasticity and Neuroplasticity in a Post-stroke Population
Status: RECRUITING
Conditions: Post-stroke Patient in Acute, Sub-acute Phase or Chronic
Interventions: OTHER: Dynamometer|OTHER: Muscle vibrations|OTHER: Muscle vibrations|OTHER: Placebo muscle vibration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improved Patient Recovery After Anesthesia With Hypercapnia Hyperpnoea
Status: COMPLETED
Conditions: Hypercapnia
Interventions: OTHER: standard of care for phase one anesthesia care|DEVICE: Quick Emergence Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Computed Tomography-guided Brachytherapy Plus Chemotherapy for Locally Recurrent Rectum Cancer
Status: COMPLETED
Conditions: Rectum Cancer
Interventions: PROCEDURE: Computed tomography guided radioactive seeds implant|DRUG: Systemic chemotherapy (FOLFIRI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CXCR4-targeted PET/CT Imaging in Hematological Malignancies
Status: RECRUITING
Conditions: CXCR4|PET/CT|Hematological Malignancy
Interventions: DRUG: 68Ga-pentixafor|DEVICE: PET/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Dexmedetomidine Sedation in Orthopedic Surgery
Status: UNKNOWN
Conditions: Hallux Valgus and Bunion|Sedation
Interventions: DRUG: Dexmedetomidine|DRUG: Midazolam|DRUG: Remifentanil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Hormonal Anabolic Deficiency and Neurovascular Alterations on Mortality in Male Patients With Heart Failure
Status: COMPLETED
Conditions: Heart Failure
Interventions: DIAGNOSTIC_TEST: Cardiopulmonary exercise test|DIAGNOSTIC_TEST: Muscle Sympathetic Nerve Activity|DIAGNOSTIC_TEST: Dual-energy X-ray absorptiometry|DIAGNOSTIC_TEST: Venous occlusion plethysmography|DIAGNOSTIC_TEST: Blood sample collection|DIAGNOSTIC_TEST: Dynamometers for Handgrip Strength
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Cabozantinib and Erlotinib for Patients With EGFR and c-Met Co-expressing Metastatic Pancreatic Adenocarcinoma
Status: TERMINATED
Conditions: Pancreatic Adenocarcinoma Metastatic
Interventions: DRUG: Cabozantinib 40 MG|DRUG: Erlotinib 100Mg Tab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Sunitinib in Combination With Bevacizumab, Carboplatin, and Paclitaxel in Patients With Advanced Non-Small Cell Lung Cancer (SABRE-L)
Status: TERMINATED
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: bevacizumab|DRUG: sunitinib|DRUG: carboplatin|DRUG: paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Effectiveness of Self Etch Adhesive and Fluoride Varnish in Reducing Hypersensitivity in Patients With Gingival Recession
Status: NOT_YET_RECRUITING
Conditions: Dentin Sensitivity
Interventions: PROCEDURE: Self etch dentin adhesive, Fluoride varnish
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: RANKL Inhibition and Mammographic Breast Density
Status: ACTIVE_NOT_RECRUITING
Conditions: Dense Breasts
Interventions: DRUG: Denosumab|DRUG: Placebo|DRUG: Calcium|DRUG: Vitamin D3|PROCEDURE: Core needle biopsy|PROCEDURE: Blood draw
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Neuromuscular Electrical Stimulation in COPD/Community Acquired Pneumonia
Status: RECRUITING
Conditions: Community-acquired Pneumonia|COPD Exacerbation Acute
Interventions: DEVICE: neuromuscular electrical stimulation (NMES)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Standard Oxygen Versus High Flow Nasal Cannula Oxygen Therapy in Patients With Acute Hypoxemic Respiratory Failure
Status: RECRUITING
Conditions: Acute Respiratory Failure|Hypoxemic Respiratory Failure
Interventions: OTHER: Standard oxygen|OTHER: High-flow nasal oxygen therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intraoperative Sedatives and Postoperative Pain
Status: COMPLETED
Conditions: Arthritis, Degenerative
Interventions: DRUG: Dexmedetomidine|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of ARRY-334543 and Docetaxel in Patients With Advanced Cancer
Status: COMPLETED
Conditions: Advanced Cancer
Interventions: DRUG: ARRY-334543, EGFR/ErbB2 inhibitor; oral|DRUG: Docetaxel, mitotic inhibitor; intravenous|DRUG: Prophylactic growth factors; subcutaneous
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Controlled Study Comparing a Short Stem Hip Prosthesis With a Stem of Standard Length
Status: COMPLETED
Conditions: Primary Osteoarthritis of Hip Nos|Secondary Osteoarthritis of Hip
Interventions: DEVICE: Total hip replacement (2 different designs)
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CORolla™ TAA for Heart Failure and Preserved Ejection Fraction and Diastolic Dysfunction
Status: UNKNOWN
Conditions: Diastolic Heart Failure NYHA Class III-IV|Diastolic Dysfunction Secondary to Aortic Stenosis
Interventions: DEVICE: CORolla™ TAA device
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study on the Efficacy of Alprostadil Injection in Patients With Acute Ischemic Stroke
Status: NOT_YET_RECRUITING
Conditions: Stroke
Interventions: DRUG: Alprostadil|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Exploratory Clinical Study of SHR-0302 and SHR-2554 in Patients With Relapsed/Refractory Peripheral T Cell Lymphoma
Status: RECRUITING
Conditions: Relapsed/Refractory Peripheral T Cell Lymphoma
Interventions: DRUG: SHR-0302|DRUG: SHR-2554
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose Escalation Trial of Re-irradiation in Good Prognosis Recurrent Glioblastoma
Status: COMPLETED
Conditions: Astrocytoma, Grade IV|Giant Cell Glioblastoma|Glioblastoma Multiforme|Gliosarcoma
Interventions: RADIATION: Radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mycophenolate-Based Therapy for Kidney Transplant Recipients Without HLA-DQ Mismatch
Status: RECRUITING
Conditions: Kidney Transplantation
Interventions: DRUG: Withdrawal of calcineurin-inhibitor, continue on concentration-controlled mycophenolate mofetil and corticosteroids.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bevacizumab Eliminates the Angiogenic Threat for Retinopathy of Prematurity
Status: UNKNOWN
Conditions: Retinopathy of Prematurity
Interventions: DRUG: Bevacizumab|PROCEDURE: Conventional Laser for ROP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Post-parotidectomy Facial Paresis: Intraoperative and Postoperative Factors
Status: COMPLETED
Conditions: Parotid Neoplasms|Facial Paralysis
Interventions: BEHAVIORAL: Facial exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Maternal Sound for Pediatric Patients Undergoing Cardiac Surgery
Status: COMPLETED
Conditions: Maternal-Fetal Relations
Interventions: BEHAVIORAL: Control group|BEHAVIORAL: Maternal sound group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate Immune Biomarker Modulation in Response to VTX-2337 in Combination With an Anti- PD-1 Inhibitor in Head and Neck Cancer
Status: TERMINATED
Conditions: Carcinoma, Squamous Cell
Interventions: DRUG: VTX-2337|DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Idelalisib (GS-1101) in Combination With Bendamustine and Rituximab for Previously Treated Indolent Non-Hodgkin Lymphomas
Status: TERMINATED
Conditions: Indolent Non-Hodgkin's Lymphomas
Interventions: DRUG: Idelalisib|DRUG: Rituximab|DRUG: Bendamustine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Survival and Autonomy With Rituximab Plus Chemotherapy or Rituximab Plus Lenalidomide for Elderly Patients With Relapsed Diffuse Large B-cell Lymphoma
Status: RECRUITING
Conditions: Chemotherapy|Diffuse Large B-Cell Lymphoma (DLBCL), Nos|Elderly
Interventions: DRUG: Rituximab|DRUG: Lenalidomide 20 MG|OTHER: Comprehensive Geriatric Assessment (CGA)|OTHER: Activities of daily living (ADL) scale
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Controlled Study of ONO-5046Na in Patients With Acute Respiratory Failure Associated With Community-Acquired Pneumonia
Status: COMPLETED
Conditions: Community-acquired Pneumonia
Interventions: DRUG: ONO-5046Na|DRUG: ONO-5046Na
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Mouth Rinses in Oral Malodor
Status: UNKNOWN
Conditions: Halitosis
Interventions: OTHER: Fluoride rinse|OTHER: Halita|OTHER: Meridol Halitosis|OTHER: Water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An RCT on Preventing Pressure Ulcers With Wheelchair Seat Cushions
Status: COMPLETED
Conditions: Pressure Ulcer
Interventions: DEVICE: Skin Protection Wheelchair Seat Cushion|DEVICE: Segmented Foam Wheelchair Seat Cushion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Different Sevoflurane Concentrations on Intraocular Pressure in Patients Undergoing Ocular Surgery Under General Anesthesia
Status: UNKNOWN
Conditions: IOP Changes Due to Anesthesia (Healthy Patients)
Interventions: DRUG: Sevoflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Safety of ArcBlate MRgHIFU in Patients With Painful Bone Metastases: An Extension Study
Status: NOT_YET_RECRUITING
Conditions: Bone Metastases
Interventions: DEVICE: ArcBlate Focused Ultrasound Ablation System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of Carbon Ion Radiotherapy Combined With Chemotherapy for Thymic Epithelial Tumors
Status: RECRUITING
Conditions: Carbon Ion Radiotherapy, Thymoma, Thymic Carcinoma, Radiotherapy, Chemotherapy
Interventions: RADIATION: carbon ion radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Andrographis Paniculata vs Boesenbergia Rotunda vs Control in Asymptomatic COVID-19
Status: UNKNOWN
Conditions: Covid19
Interventions: DRUG: Andrographis Paniculata|DRUG: Boesenbergia|OTHER: Standard supportive treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Iberdomide, Bortezomib, Dexamethasone With Isatuximab Added on Demand for ND-NTE MM Patients
Status: NOT_YET_RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: Iberdomide|DRUG: Bortezomib|DRUG: Dexamethasone|DRUG: Isatuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Mandala Technique on Acute Nausea-vomiting and Comfort Level in Cancer Patients
Status: ENROLLING_BY_INVITATION
Conditions: Chemotherapy-induced Nausea and Vomiting|Nursing Caries
Interventions: OTHER: MANDALA TECHNIQUE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: RIOTC: Reducing the Impact of Ovarian Stimulation. Novel Approaches to Luteal Support in IVF-Study 2
Status: COMPLETED
Conditions: IVF
Interventions: DRUG: Letrozole 5 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transphyseal Vs. Physeal Sparing ACL Reconstruction in Skeletally Immature Patients: Risk of Subsequent Lower Extremity Growth Deformity
Status: COMPLETED
Conditions: ACL Reconstruction
Interventions: DIAGNOSTIC_TEST: Bilateral hip to ankle x-ray, exam and strength testing.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Efficacy of Coenzyme Q10 And Curcumin in Patients With Myelodysplastic Syndromes
Status: WITHDRAWN
Conditions: Myelodysplastic Syndrome
Interventions: DRUG: curcumin; coenzyme q10
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Amifostine to Protect From Side Effects of PSCT in Treating Patients With Solid Tumors
Status: TERMINATED
Conditions: Brain and Central Nervous System Tumors|Childhood Germ Cell Tumor|Chordoma|Kidney Cancer|Liver Cancer|Neuroblastoma|Ovarian Cancer|Retinoblastoma|Sarcoma
Interventions: DRUG: amifostine trihydrate|DRUG: busulfan|DRUG: filgrastim|DRUG: melphalan|DRUG: thiotepa|PROCEDURE: peripheral blood stem cell transplantation (PBSC)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: COVID-19 Vaccine Text Outreach
Status: COMPLETED
Conditions: Covid19
Interventions: BEHAVIORAL: Opt-In (Call-Back)|BEHAVIORAL: Opt-in (In-Bound)|BEHAVIORAL: Standard Message|BEHAVIORAL: Clinician Endorsement|BEHAVIORAL: Scarcity|BEHAVIORAL: Opt-Out Framing|BEHAVIORAL: Phone Call
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: 6,8-Bis(Benzylthio)Octanoic Acid, Cytarabine, and Daunorubicin Hydrochloride in Treating Older Patients With Newly Diagnosed Acute Myeloid Leukemia
Status: WITHDRAWN
Conditions: Untreated Adult Acute Myeloid Leukemia
Interventions: DRUG: 6,8-Bis(benzylthio)octanoic Acid|DRUG: Cytarabine|DRUG: Daunorubicin Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase III Trial to Evaluate the Efficacy and Safety of Gemigliptin 50mg qd Added to Ongoing Glimepiride as Fix-dose Combination in Patients With Type 2 Diabetes
Status: UNKNOWN
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Gemigliptin/Glimepiride combination
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1b Study of WU-NK-101 in Combination With Cetuximab
Status: RECRUITING
Conditions: Colorectal Cancer Metastatic|Squamous Cell Carcinoma of Head and Neck
Interventions: BIOLOGICAL: WU-NK-101 - Dose Escalation|DRUG: Cetuximab - Dose Escalation|BIOLOGICAL: WU-NK-101 - Cohort Expansion|BIOLOGICAL: Cetuximab - Cohort Expansion
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Physiotherapy Treatment Following Gynaecological Surgery
Status: COMPLETED
Conditions: Vaginal Hysterectomy|Pelvic Organ Prolapse Vaginal Surgery
Interventions: BEHAVIORAL: Pelvic floor muscle training and lifestyle modification
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Telecommunication Via Cell Phones During Post-Operative Treatment After Lung Transplantation
Status: COMPLETED
Conditions: Lung Transplantation
Interventions: DEVICE: Home spirometry with data transfer via cell phone|DEVICE: Home spirometer with BT-cellphone|DEVICE: Home spirometer w/o BT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Exhaled Breath Olfactory Signature of Pulmonary Arterial Hypertension
Status: COMPLETED
Conditions: Pulmonary Hypertension
Interventions: DEVICE: Exhaled Breath Olfactory Signature (Artificial Nose)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Digital Health Interventions for Obsessive Compulsive Disorder (OCD)
Status: ACTIVE_NOT_RECRUITING
Conditions: Obsessive-Compulsive Disorder
Interventions: DEVICE: Perspectives OCD|DEVICE: The Health and Well-Being Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Brain Functional Changes With 18F-FDG PET and Cognitive Processes After Brain Radiotherapy for Cavernous Sinus Meningiomas and Non-secreting ACTH Adenomas
Status: COMPLETED
Conditions: Meningioma
Interventions: DIAGNOSTIC_TEST: PET CT with 18 FDG .
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Sodium Bicarbonate on Postoperative Renal Function in Infective Endocarditis Patients Undergoing Open Heart Surgery
Status: COMPLETED
Conditions: Acute Kidney Injury
Interventions: DRUG: sodium bicarbonate|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Heterologous Effect of Diptheria, Tetanus, Acellular Pertussis Vaccination on Influenza Challenge in the Elderly
Status: UNKNOWN
Conditions: Heterologous Effects of Vaccines
Interventions: BIOLOGICAL: Seasonal influenza vaccine|BIOLOGICAL: Diphtheria-tetanus-acellular pertussis vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: TEG Anticoagulation Monitoring During ECMO
Status: COMPLETED
Conditions: Extracorporeal Membrane Oxygenation Complication
Interventions: DEVICE: TEG monitoring|DEVICE: APTT monitoring|DRUG: Heparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Randomized Trial Comparing Misoprostol and Foley Bulb for Labor Induction in the Preterm Gestation
Status: COMPLETED
Conditions: Premature Birth|Cervical Ripening
Interventions: DRUG: Misoprostol|DEVICE: Foley bulb
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Using White Noise, Embracing and Facilitated Tucking in Newborns
Status: COMPLETED
Conditions: Pain
Interventions: OTHER: Heel Lance Blood Sampling in Facilitated Tucking Position|OTHER: Heel Lance Blood Sampling When the Infant is Embraced by the Mother|OTHER: Heel Lance Blood Sampling Using White Noise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Postoperative Cesarean Delivery Pain Relief; Diclofenac Versus Bupivacaine
Status: COMPLETED
Conditions: Cesarean Delivery
Interventions: DRUG: Bupivacaine|DRUG: Diclofenac
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Influence of Coronary Chronic Total Occlusion on Myocardial Perfusion on Computed Tomography
Status: COMPLETED
Conditions: Coronary Occlusion|Myocardial Ischemia|Myocardial Perfusion Imaging|Percutaneous Coronary Intervention
Interventions: DIAGNOSTIC_TEST: computed tomography perfusion imaging
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Efficacy of Exjade in the Treatment of Transfusion-dependent Iron Overload in Aplastic Anemia Patients
Status: TERMINATED
Conditions: Aplastic Anemia
Interventions: DRUG: ICL670|DRUG: Chelation|DRUG: No chelation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lymphatic and Systemic Immunity Changes in Post-radiation Lymphedema Development
Status: COMPLETED
Conditions: Lymphedema
Interventions: DRUG: Indocyanine Green (ICG)|DEVICE: Near-infrared Fluorescence Lymphatic Imaging (NIRFLI)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Impact of Artificial Intelligence Dietary Smartphone Application on Nutritional Status Among Cancer Patients
Status: COMPLETED
Conditions: Malnutrition, Calorie|Malnutrition; Protein|Weight Change, Body
Interventions: DEVICE: artificial intelligence dietary android mobile application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Use of the ExVent Accessory With the O2Vent Optima Oral Appliance for the Treatment of Obstructive Sleep Apnea
Status: RECRUITING
Conditions: Sleep Apnea, Obstructive|Sleep-Disordered Breathing
Interventions: DEVICE: ExVent
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Combination of Talquetamab and Teclistamab in Participants With Relapsed or Refractory Multiple Myeloma
Status: RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: Talquetamab|DRUG: Teclistamab|DRUG: Daratumumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combined Vitrectomy and Triamcinolone in Macular Edema Secondary to Branch Retinal Vein Occlusion (BRVO)
Status: TERMINATED
Conditions: Branch Retinal Vein Occlusion|Macular Edema
Interventions: PROCEDURE: Grid Laser|PROCEDURE: Vitrectomy and 20 mg triamcinolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Topical rhThrombin as an Adjunct to Hemostasis During Segmental Hepatectomy
Status: COMPLETED
Conditions: Hepatectomy
Interventions: DRUG: rhThrombin ( Topical )|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of SY 5609, a Selective CDK7 Inhibitor, in Advanced Solid Tumors
Status: COMPLETED
Conditions: Advanced Solid Tumor|Breast Cancer|Small-cell Lung Cancer|Pancreatic Cancer
Interventions: DRUG: SY-5609|DRUG: Fulvestrant|DRUG: Gemcitabine|DRUG: Nab-paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immuno-epidemiological and Socio-behavioral Evaluation of Release of Sterile Male Aedes Albopictus Mosquitoes on Human-vector Contacts
Status: UNKNOWN
Conditions: Mosquito Bite
Interventions: OTHER: sterile insect technique (TIS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Role of Occult Cardiac Amyloid in the Elderly With Aortic Stenosis.
Status: UNKNOWN
Conditions: Cardiac Amyloidosis|Aortic Stenosis
Interventions: OTHER: Baseline assessment|PROCEDURE: Transthoracic echocardiography|PROCEDURE: 99mTc-3,3-diphosphono-1,2-propanodicarboxylic acid scintigraphy|RADIATION: CT 3-5-minute post-contrast research sequences|PROCEDURE: Cardiac Magnetic Resonance|PROCEDURE: Endomyocardial biopsy|OTHER: Follow-up assessment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Proposal to Evaluate the Efficacy of the InterX 5000 in the Treatment of Chronic Neck and Shoulder Pain
Status: COMPLETED
Conditions: Neck Pain|Shoulder Pain|Cervical Pain
Interventions: DEVICE: Inactive InterX 5000|DEVICE: InterX 5000 Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of the First French Psychoeducational Program on Unipolar Depression
Status: UNKNOWN
Conditions: Unipolar Depressed Outpatients|Mild Severity|Without Psychotic Features
Interventions: OTHER: Treatment as usual|BEHAVIORAL: ENVIE psychoeducational program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Functional Microarray Augmentation of Skin Treatment With Lidocaine
Status: WITHDRAWN
Conditions: Pain Perception|Phlebotomy
Interventions: DRUG: 4% lidocaine gel application with sham microneedle device|DRUG: Microneedle-facilitated lidocaine application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ph 3 Safety/Efficacy Study of Rolapitant for Prevention of CINV in Subjects Receiving Moderately Emetogenic Chemotherapy
Status: COMPLETED
Conditions: Chemotherapy-induced Nausea and Vomiting
Interventions: DRUG: Rolapitant|DRUG: Granisetron|DRUG: Dexamethasone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Sleep Deprivation and Recovery Sleep on Emotional Memory and Affective Reactivity
Status: RECRUITING
Conditions: Sleep Deprivation|Sleep
Interventions: BEHAVIORAL: Sleep Deprivation|BEHAVIORAL: Daytime nap
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Stellate Ganglion Block in Beating Heart Surgery
Status: UNKNOWN
Conditions: Cardiac Arrythmias
Interventions: DRUG: stellate ganglion block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Optometric Follow-up After Cataract Surgery
Status: WITHDRAWN
Conditions: Cataract|Age-related Cataract
Interventions: PROCEDURE: Intervention Group cataract follow up|PROCEDURE: Usual Care consultant follow up
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study to Assess Enzastaurin + R-CHOP in Subjects With DLBCL With the Genomic Biomarker DGM1™
Status: COMPLETED
Conditions: Diffuse Large B-Cell Lymphoma
Interventions: DRUG: Enzastaurin Hydrochloride|OTHER: R-CHOP + placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Targeting Physical Activity to Improve Cardiovascular Health in Type 2 Diabetes
Status: COMPLETED
Conditions: Motor Activity|Health Behavior|Diabetes Mellitus, Type 2
Interventions: BEHAVIORAL: Physical Activity|BEHAVIORAL: Questionnaires
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Different Montages of tDCS Combined With Dual-task Training on EEG Microstates
Status: RECRUITING
Conditions: Stroke
Interventions: DEVICE: Transcranial direct current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 3D Facial Scanning for Evaluating Autologous Fat Grafting in Craniofacial Deformities
Status: NOT_YET_RECRUITING
Conditions: Adipocytes|Autografts|Imaging, Three-Dimensional / Methods
Interventions: DIAGNOSTIC_TEST: 3dMD technology
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Healthy Caregivers-Healthy Children
Status: ACTIVE_NOT_RECRUITING
Conditions: Obesity|Child, Only
Interventions: BEHAVIORAL: Healthy Caregivers- Healthy children|BEHAVIORAL: Jump Start
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Procrit (Epoetin Alfa) on Preventing Delayed Graft Function After Deceased Donor Renal Transplantation
Status: COMPLETED
Conditions: Delayed Graft Function
Interventions: DRUG: Epoetin Alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Immediate Treatment vs Colposcopic Follow-up for Biopsy-Proven CIN 1
Status: COMPLETED
Conditions: Cervical Intraepithelial Neoplasia
Interventions: PROCEDURE: loop electrosurgical excision procedure (LEEP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Piroxicam Premedication for Postendodontic Pain in Non-vital Mandibular Molars
Status: UNKNOWN
Conditions: Non-Vital Tooth
Interventions: DRUG: Piroxicam|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Future Foundation 2.0 Personal Responsibility Education Innovative Strategies (PREIS) Program
Status: UNKNOWN
Conditions: Teen Pregnancy|Pregnancy in Adolescence|Teen Pregnancy Prevention|Pregnancy Prevention|Sexually Transmitted Diseases
Interventions: BEHAVIORAL: Future Foundation 2.0 PREIS Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Chemotherapy in Treating Patients With Advanced Sarcoma
Status: COMPLETED
Conditions: Ovarian Cancer|Sarcoma
Interventions: BIOLOGICAL: filgrastim|DRUG: doxorubicin hydrochloride|DRUG: ifosfamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High-Dose Immunosuppression and Autologous Transplantation for Multiple Sclerosis (HALT MS) Study
Status: COMPLETED
Conditions: Relapsing-Remitting Multiple Sclerosis
Interventions: DRUG: Granulocyte-colony stimulating factor (G-CSF) and prednisone|DRUG: Carmustine, etoposide, cytarabine, and melphalan (BEAM)|PROCEDURE: Autologous hematopoietic stem cell transplant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Pharmacokinetics (PK), Pharmacodynamics (PD), and Usability of Abaloparatide-solid Microstructured Transdermal System (sMTS) in Postmenopausal Women With Low Bone Mineral Density (BMD)
Status: COMPLETED
Conditions: Postmenopausal Osteoporosis
Interventions: COMBINATION_PRODUCT: abaloparatide-sMTS
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Subcutaneous Injection and Ultrasonic Dispersion of Cefazolin Into Chronic Pelvic-Region Pressure Ulcers in Persons With Spinal Cord Injury
Status: COMPLETED
Conditions: Spinal Cord Injury|Chronic Pressure Ulcers
Interventions: DEVICE: Ultrasonic Distribution of Cefazolin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Increasing the Impact of a School Prevention Program Among Young Adolescents by Adding a Teacher Component
Status: UNKNOWN
Conditions: Primary Prevention
Interventions: BEHAVIORAL: Experimental: "Young Millie" prevention program, active teachers|BEHAVIORAL: Prevention program: "Young Mili", non active teachers
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Pilot Phase for an Acute Evaluation of a Non-Implantable Electrical Continence Device
Status: COMPLETED
Conditions: Urinary Bladder, Overactive
Interventions: DEVICE: The FemPulse System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Prophylactic Intravesical Chemotherapy to Prevent Bladder Recurrence After Diagnostic Ureteroscopy for Primary Upper Tract Urothelial Carcinoma Patients
Status: UNKNOWN
Conditions: Upper Tract Urothelial Carcinoma|Bladder Recurrence
Interventions: DRUG: Pirarubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Hormonal Influences on Diuresis
Status: COMPLETED
Conditions: Nocturia|Menopause|LUTS|Diuresis
Interventions: DIAGNOSTIC_TEST: ICIQ FLUTS Questionaires|DIAGNOSTIC_TEST: Frequency Volume Chart|DIAGNOSTIC_TEST: Renal Function Profile|DIAGNOSTIC_TEST: Blood Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Laparoscopic Cholecystectomy Using Airseal in Children
Status: COMPLETED
Conditions: Gall Stones (& [Calculus - Gall Bladder])|Cholecystitis, Acute|Cholecystitis, Chronic|Pancreatitis Due to Gallstones|Child, Only
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pharmacokinetics, Safety and Tolerability Study of PF-03463275 in Healthy Male Japanese and Western Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: PF-03463275|DRUG: PF-03463275|DRUG: PF-03463275|DRUG: Placebo|DRUG: PF-03463275|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Effects of a Single Intravitreal Injection of vMCO-010 Optogenetic Therapy in Subjects With Stargardt Disease
Status: COMPLETED
Conditions: Stargardt Disease
Interventions: BIOLOGICAL: Gene Therapy-vMCO-010
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Novel Analgesia Technique for ACL Reconstruction
Status: ACTIVE_NOT_RECRUITING
Conditions: Anterior Cruciate Ligament Injury
Interventions: DRUG: Bupivacaine|DEVICE: Ultrasound|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of iDEAL in Improving the Knowledge, Attitude, Practice, Environmental Cleanliness Index and Dengue Index
Status: NOT_YET_RECRUITING
Conditions: Knowledge, Attitudes, Practice
Interventions: BEHAVIORAL: THEORY BASED INTEGRATED DENGUE EDUCATION AND LEARNING MODULE (iDEAL)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Multicenter Selective Screening Study to Investigate the Frequency of Neuronal Ceroid Lipofuxinosis Type 2 (CLN2)
Status: RECRUITING
Conditions: Neuronal Ceroid Lipofuxinosis Type2 (CLN2)
Interventions: GENETIC: Blood Sampling
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Screening for Abdominal Aortic Aneurysms in the General Practice by Ultraportable Ultrasound
Status: RECRUITING
Conditions: Abdominal Aortic Aneurysm
Interventions: OTHER: AAA screening by a GP|OTHER: AAA screening by a radiologist
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Do Antipsychotic Agents Induce Supersensitivity in Humans: A Combined PET/MRI Study in Patients With Schizophrenia
Status: RECRUITING
Conditions: Schizophrenia
Interventions: RADIATION: Single PET/MR-measurement
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Gemcitabine, Cisplatin and Nab-Paclitaxel as Neoadjuvant Treatment for Patients With Resectable or Borderline Resectable Pancreatic Cancer
Status: RECRUITING
Conditions: Borderline Resectable Pancreatic Ductal Adenocarcinoma|Resectable Pancreatic Adenocarcinoma|Stage I Pancreatic Cancer AJCC v8|Stage II Pancreatic Cancer AJCC v8|Stage III Pancreatic Cancer AJCC v8
Interventions: PROCEDURE: Biopsy|PROCEDURE: Biospecimen Collection|DRUG: Cisplatin|PROCEDURE: Computed Tomography|DRUG: Gemcitabine|PROCEDURE: Magnetic Resonance Imaging|DRUG: Nab-paclitaxel|PROCEDURE: Pancreatic Surgical Procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adhesion Performance Study of Lidocaine Topical System 1.8% Compared to Generic Lidocaine Patch 5% in Healthy, Adult, Human Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: lidocaine topical system 1.8%|DRUG: lidocaine patch 5%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT