pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Rapid On Site Evaluation of Pleural Touch Preparations in Diagnosing Malignant Pleural Effusion in Patients Undergoing Pleuroscopy
Status: ACTIVE_NOT_RECRUITING
Conditions: Malignant Neoplasm|Malignant Respiratory Tract Neoplasm|Malignant Thoracic Neoplasm
Interventions: PROCEDURE: Biopsy|OTHER: Medical Chart Review|PROCEDURE: Thoracoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study of the Effectiveness of Mental Contrasting and Implementation Intention in the Management of Apathy in Schizophrenia
Status: UNKNOWN
Conditions: Schizophrenia|Apathy
Interventions: BEHAVIORAL: CM-II|BEHAVIORAL: Psychoeducation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of the Effectiveness of a Nursing Intervention Program in Reducing Anxiety in Users Who Perform Scheduled Sessions in the Hyperbaric Chamber
Status: RECRUITING
Conditions: Anxiety and Fear|Nurse's Role
Interventions: BEHAVIORAL: Intervention group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: TRPM8 in Acute Ischemic Stroke by Topical Menthol
Status: NOT_YET_RECRUITING
Conditions: Ischemic Stroke
Interventions: DRUG: Menthol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Salvage Radiotherapy Combined With Hormonotherapy in Oligometastatic Pelvic Node Relapses of Prostate Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Cancer
Interventions: DRUG: ELIGARD
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Double Blinded, Prospective, Randomized, Vehicle Controlled Multi-center Study of Photodynamic Therapy With Visonac® Cream in Patients With Acne Vulgaris
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: Visonac PDT|DRUG: Vehicle cream with PDT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Denosumab in the Prevention of Bone Loss in Non-menopausal Women With Anorexia Nervosa
Status: TERMINATED
Conditions: Anorexia Nervosa
Interventions: DRUG: Denosumab subcutaneous injections|DRUG: Placebo subcutaneous injections
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigation of the Genetics of Hematologic Diseases
Status: RECRUITING
Conditions: Bone Marrow Failure Syndromes|Erythrocyte Disorder|Leukocyte Disorder|Hemostasis|Blood Coagulation Disorder|Sickle Cell Disease|Dyskeratosis Congenita|Diamond-Blackfan Anemia|Congenital Thrombocytopenia|Severe Congenital Neutropenia|Fanconi Anemia|Myelodysplastic Syndromes|Myeloproliferative Diseases
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pathophysiological Mechanisms of Hypertensive LVH:Optimising Regression
Status: COMPLETED
Conditions: Hypertension|Left Ventricular Hypertrophy
Interventions: DRUG: Bendroflumethiazide 2.5mg OD; Amlodipine 10mg OD|DRUG: Valsartan 160mg OD; Moxonidine 400mcg OD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Controlled Study of the Occurrence of Actinic Keratosis on the Face After Cryotherapy + Aminolevulinic Acid (ALA) Photodynamic Therapy
Status: COMPLETED
Conditions: Actinic Keratosis
Interventions: DRUG: Aminolevulinic Acid|DRUG: Topical Solution Vehicle|DEVICE: BLU-U|PROCEDURE: Cryotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Chronic Periodontitis With Repeated Adjunctive Antimicrobial Photodynamic Therapy
Status: COMPLETED
Conditions: Chronic Periodontitis
Interventions: PROCEDURE: Photodynamic Therapy|PROCEDURE: Sham Photodynamic Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Synergistic Effect of Vitamin E & D in Reducing Risk of Effects Associated With Atypical Anti-psychotics
Status: COMPLETED
Conditions: Antipsychotics and Neuroleptics Toxicity
Interventions: DRUG: Risperidone|DRUG: Olanzapine|DRUG: Quetiapine|DRUG: Risperidone and Vitamin D and Vitamin E|DRUG: Olanzapine and Vitamin D and Vitamin E|DRUG: Quetiapine and Vitamin D and Vitamin E
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Glycyrrhetinic Acid-Effect on Serum Potassium and Insulin Resistance in Dialysis Patients
Status: COMPLETED
Conditions: End Stage Renal Disease
Interventions: DRUG: oral 18B Glycyrrhetinic acid versus placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: The Effects Of Probiotics On Stress Among Healthy Adults From Umm Al-Qura University At Makkah
Status: COMPLETED
Conditions: Stress|Constipation|Anthropometry|Bowel Disease
Interventions: DIETARY_SUPPLEMENT: Probiotics (Lactobacillus rhamnosus GG (ATCC 53103)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oxaliplatin, Capecitabine and Endostar as First Line Treatment for Patients With Advanced Colorectal Cancer
Status: UNKNOWN
Conditions: Advanced Colorectal Cancer
Interventions: DRUG: OXCE|DRUG: Endostar
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Embolization of Middle Meningeal Artery for Subdural Hematoma in Canada (EMMA Can)
Status: RECRUITING
Conditions: Subdural Hematoma
Interventions: PROCEDURE: Embolization of the middle meningeal artery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Safety of Ovarian Preservation in Stage IA Endometrial Carcinoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Endometrial Neoplasms
Interventions: PROCEDURE: TH|PROCEDURE: TH/BSO|PROCEDURE: BPLND
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neuroimaging of Diet in ADHD: Phase I
Status: COMPLETED
Conditions: Attention Deficit Disorder With Hyperactivity
Interventions: DIETARY_SUPPLEMENT: Restricted Diet|DIETARY_SUPPLEMENT: Ruse Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SVT-15652 Otic Solution for the Treatment of Otomycosis
Status: COMPLETED
Conditions: Otomycosis
Interventions: DRUG: SVT-15652|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Person-centred Interactive Self-management Support in Primary Healthcare for People With Type 2 Diabetes
Status: UNKNOWN
Conditions: Diabetes Type 2
Interventions: BEHAVIORAL: Intervention arm: Person-centred interactive self-management support|OTHER: Control arm|OTHER: External comparison group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: At-Home Dermoscopy Artificial Intelligence
Status: RECRUITING
Conditions: Malignant Skin Neoplasm
Interventions: OTHER: Dermoscopy|OTHER: Digital Photography|PROCEDURE: Self-Skin Examination|DEVICE: Skin Examination with Sklip|PROCEDURE: Skin Examination|OTHER: Survey Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Docetaxel, Cisplatin, and Erlotinib Hydrochloride in Treating Patients With Stage I-III Non-small Cell Lung Cancer Following Surgery
Status: COMPLETED
Conditions: Recurrent Lung Non-Small Cell Carcinoma|Stage IA Lung Non-Small Cell Carcinoma AJCC v7|Stage IB Lung Non-Small Cell Carcinoma AJCC v7|Stage IIA Lung Non-Small Cell Carcinoma AJCC v7|Stage IIB Lung Non-Small Cell Carcinoma AJCC v7|Stage IIIA Lung Non-Small Cell Cancer AJCC v7|Stage IIIB Lung Non-Small Cell Cancer AJCC v7
Interventions: DRUG: Cisplatin|DRUG: Docetaxel|DRUG: Erlotinib|DRUG: Erlotinib Hydrochloride|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Natural Sounds on Attention Restoration in Noisy Environment
Status: RECRUITING
Conditions: Cognitive Fatigue|Mental Fatigue|Heart Rate Variability|Skin Conductance|Behavioral Performance|Positive and Negative Affect|Inhibition|Working Memory|Perceived Restoration
Interventions: OTHER: Baseline|OTHER: Fatigue Manipulation|OTHER: Traffic Sound|OTHER: Traffic and Masking Sound|OTHER: Silence
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Short-term Fasting Prior to PD-1/PD-L1 Inhibitor Therapy for of Advanced or Metastatic Skin Malignancy
Status: RECRUITING
Conditions: Advanced Malignant Skin Neoplasm|Metastatic Malignant Skin Neoplasm
Interventions: DRUG: Atezolizumab|DRUG: Avelumab|BIOLOGICAL: Cemiplimab|BIOLOGICAL: Durvalumab|BIOLOGICAL: Nivolumab|BIOLOGICAL: Pembrolizumab|OTHER: Quality-of-Life Assessment|OTHER: Short-Term Fasting
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Fear and Avoidance in PTSD Patients
Status: RECRUITING
Conditions: Post Traumatic Stress Disorder
Interventions: OTHER: Fear Conditioning|OTHER: Avoidance conditioning|OTHER: Pavlovian fear extinction learning|OTHER: Willingness to pay to avoid shock
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pilot Study of Fosamax in Spinal Cord Injury
Status: TERMINATED
Conditions: Spinal Cord Injury|Osteoporosis
Interventions: DRUG: Fosamax|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Optimal Order of Concurrent Office Hysteroscopy and Endometrial Biopsy
Status: COMPLETED
Conditions: Uterine Fibroids|Vaginal Bleeding
Interventions: PROCEDURE: Office hysteroscopy|PROCEDURE: Endometrial biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Radiotherapy With Neoadjuvant Chemotherapy and Immunotherapy in Rectal Cancer
Status: SUSPENDED
Conditions: Rectal Cancer|Radiotherapy|Immunotherapy|Organ Preservation
Interventions: DRUG: Chemotherapy|DRUG: Immunotherapy|RADIATION: IMRT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Ruxolitinib in Sclerotic Chronic Graft-Versus-Host Disease After Failure of Systemic Glucocorticoids
Status: COMPLETED
Conditions: Graft-versus-host-disease (GVHD)
Interventions: DRUG: Ruxolitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Describe the Pharmacokinetics of Acyclovir in Premature Infants (PTN_Acyclo)
Status: COMPLETED
Conditions: Herpes Simplex Virus|Neonatal Sepsis
Interventions: DRUG: Acyclovir
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Examining Expectancy Challenges to Prevent Nonmedical Prescription Stimulant Use
Status: COMPLETED
Conditions: Prescription Drug Abuse (Not Dependent)
Interventions: BEHAVIORAL: Caffeine-Based Expectancy Challenge|BEHAVIORAL: Placebo-Based Expectancy Challenge
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: PaNeX: Partial Nephrectomy Under Xenon
Status: COMPLETED
Conditions: Renal Function After Partial Nephrectomy
Interventions: DRUG: Xenon|DRUG: Isoflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized Study Evaluating the Therapeutic Equivalence of Two Butoconazole Nitrate Vaginal Cream, 2% Formulations
Status: COMPLETED
Conditions: Vulvovaginal Candidiasis
Interventions: DRUG: Butoconazole Nitrate Vaginal Cream|DRUG: Placebo|DRUG: Gynazole 1 vaginal cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Study of ASTX727 Plus Talazoparib in Patients With Triple Negative or Hormone Resistant/HER2-negative Metastatic Breast Cancer
Status: COMPLETED
Conditions: Metastatic Breast Cancer|Triple Negative Breast Cancer|Hormone Receptor Positive Tumor
Interventions: DRUG: Talazoparib|DRUG: ASTX727
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: the Effect of Erector Spinae Plane Block on Fentanyl Consumption During Abdominal Hysterectomy
Status: COMPLETED
Conditions: Post Operative Pain
Interventions: PROCEDURE: ESP block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pharmacokinetic Study of CPT-11, Raltegravir and Midazolam With Characterisation of UGT1A1 Genotype
Status: COMPLETED
Conditions: Solid Tumor
Interventions: DRUG: CPT-11, Raltegravir (Isentress®), Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Cow Milk and 15% Hypertonic Saline in the Treatment of Rectal Prolapse in Children
Status: COMPLETED
Conditions: Rectal Prolapse
Interventions: DRUG: Hypertonic saline|OTHER: Cow Milk
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of LGD-6972 in Healthy Subjects and Subjects With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: LGD-6972|DRUG: Placebo (Captisol®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study To Evaluate The Immunogenicity And Safety Of r-hIFN Beta-1a (Rebif®) Using Clone 484-39 In Multiple Sclerosis
Status: COMPLETED
Conditions: Relapsing Remitting Multiple Sclerosis
Interventions: BIOLOGICAL: Rebif® (clone 484-39)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of COVID-19 After Autologous Hematopoietic Stem Cell Transplantation in Sweden
Status: COMPLETED
Conditions: Covid19|Myeloma Multiple|Malignant Lymphoma|Hematologic Neoplasms|Stem Cell Transplant Complications
Interventions: OTHER: Autologous stem cell transplantation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Role of Biodentine in Class V Dental Lesions on Oral Health Related Quality of Life
Status: TERMINATED
Conditions: Quality of Life|Cervical Abrasion
Interventions: DEVICE: Photac-fil|DEVICE: Biodentine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare the Safety and Drug Levels in Blood When Using Various Forms of GSK189075 Given to Healthy Subjects
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus|Diabetes Mellitus, Type 2
Interventions: DRUG: GSK189075 (Modified and immediate release formulations)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nanodropper Use in Primary Open-Angle Glaucoma Patients: A Non-Inferiority Trial
Status: RECRUITING
Conditions: Ocular Hypertension|Primary Open Angle Glaucoma
Interventions: DEVICE: Nanodropper|DEVICE: Regular dropper
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Parents Together: Supporting Parents to Promote Healthy Behaviours in Children
Status: NOT_YET_RECRUITING
Conditions: Child Eating Behaviours|Child Nutrition|Early Child Development|Parenting
Interventions: BEHAVIORAL: Parents Together parenting course
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Examining 3,4-methylenedioxymethamphetamine (MDMA) Effects on Psychological, Relational and Hyperarousal-Related Neural Reactivity Mechanisms in Veterans With PTSD and Moral Injury
Status: RECRUITING
Conditions: PTSD, Post Traumatic Stress Disorder|Moral Injury
Interventions: DRUG: MDMA-AT|BEHAVIORAL: SEA-IT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Extension Study of a Second Course of a Digital Therapeutic for the Treatment of Experiential Negative Symptoms of Schizophrenia
Status: RECRUITING
Conditions: Schizophrenia|Negative Symptoms in Schizophrenia
Interventions: DEVICE: Study App
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: rSIFN-co Among Healthy Subjects and Subjects With Mild or Asymptomatic COVID-19
Status: ACTIVE_NOT_RECRUITING
Conditions: COVID-19|SARS-CoV-2 Infection
Interventions: DRUG: rSIFN-co Nasal Spray|DRUG: rSIFN-co Nasal Spray|DRUG: Placebo Nasal Spray|DRUG: Placebo Nasal Spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Maintenance Treatment With Bevacizumab and Atezolizumab for Ovarian Cancer
Status: WITHDRAWN
Conditions: Ovarian Endometrioid Tumor|Fallopian Tube Cancer|Primary Peritoneal Cancer|TP53 Mutation
Interventions: DRUG: Atezolizumab|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Allogeneic CD30 Chimeric Antigen Receptor Epstein-Barr Virus-Specific T Lymphocytes in Relapsed or Refractory CD30-Positive Lymphomas
Status: WITHDRAWN
Conditions: Extranodal Natural Killer/T-Cell Lymphoma, Nasal Type|Classical Hodgkin Lymphoma
Interventions: BIOLOGICAL: CD30.CAR-EBVST cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Stenting Versus Best Medical Therapy for Treatment of Ostial Renal Artery Stenosis: a Trial in Patients With Advanced Atherosclerosis
Status: UNKNOWN
Conditions: Renal Artery Stenosis
Interventions: DEVICE: Herkulink renal artery Stent|OTHER: best medical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Patient Education to Improve Pain Management in Older Adults With Acute Musculoskeletal Pain: A Pilot Randomized Trial
Status: COMPLETED
Conditions: Musculoskeletal Pain
Interventions: BEHAVIORAL: Video|BEHAVIORAL: Phone follow-up
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Focal ExAblate MR-Guided Focused Ultrasound Treatment for Management of Organ-Confined Intermediate Risk Prostate Cancer
Status: TERMINATED
Conditions: Prostate Cancer
Interventions: DEVICE: ExAblate MRgFUS
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CARE Network Maintenance Versus Intermittent Inhaled Steroids in Wheezing Toddlers (MIST)
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Budesonide|DRUG: Placebo Budesonide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Post Marketing Study of Angel of Water™ for Colon Cleansing as Preparation for Colonoscopy
Status: UNKNOWN
Conditions: Colon Diseases
Interventions: DEVICE: Colon cleansing by hydrotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Human Amniotic Tissue-derived Allograft, NuCel, in Posteriolateral Lumbar Fusions for Degenerative Disc Disease
Status: TERMINATED
Conditions: Lumbar Degenerative Disc Disease|Spinal Stenosis|Spondylolisthesis|Spondylosis|Intervertebral Disk Displacement|Intervertebral Disk Degeneration|Spinal Diseases|Bone Diseases|Musculoskeletal Diseases|Spondylolysis
Interventions: BIOLOGICAL: NuCel|BIOLOGICAL: Demineralized Bone Matrix
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Citrulline Efficacy to Improve Carbohydrate Metabolism Abnormalities in the Patient Treated With High Doses of Statin
Status: COMPLETED
Conditions: Atorvastatin
Interventions: DIETARY_SUPPLEMENT: citrulline supplementation|DIETARY_SUPPLEMENT: placebo supplementation|PROCEDURE: glucose tolerance test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Perineal Trauma After Jet Ski Accidents and Long-term Functional Outcomes Results
Status: RECRUITING
Conditions: Perineum; Tear, Traumatic|Anal Tear|Anal Incontinence
Interventions: PROCEDURE: Patients who experienced an ano-perineal trauma following a PWC/Jet-Ski accident
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Efficacy of Asfotase Alfa in Juvenile Patients With Hypophosphatasia (HPP)
Status: COMPLETED
Conditions: Hypophosphatasia (HPP)
Interventions: BIOLOGICAL: asfotase alfa|BIOLOGICAL: asfotase alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dual Target CAR-T Cell Treatment for Refractory Systemic Lupus Erythematosus (SLE) Patients
Status: RECRUITING
Conditions: CAR-T Cell Therapy
Interventions: DRUG: GC012F injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Dexlansoprazole in Healing and Maintenance of Healed Erosive Esophagitis (EE) in Children
Status: RECRUITING
Conditions: Erosive Esophagitis
Interventions: DRUG: Dexlansoprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ferric Carboxymaltose to Improve Skeletal Muscle Metabolism in Heart Failure Patients With Functional Iron Deficiency
Status: TERMINATED
Conditions: Iron-deficiency
Interventions: DRUG: Ferric Carboxymaltose|DRUG: Placebo|DEVICE: 31P MRS/MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A First-In-Human, Phase 1 Study Evaluating Oral TACC3 PPI Inhibitor, AO-252, in Advanced Solid Tumors
Status: RECRUITING
Conditions: Triple Negative Breast Cancer|High Grade Serous Ovarian Cancer|Endometrial Cancer
Interventions: DRUG: AO-252
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pelvic Floor Muscle Training With and Without Hypopressive Exercises in Postmenopausal Females.
Status: COMPLETED
Conditions: Pelvic Organ Prolapse
Interventions: OTHER: hypopressive exercises|OTHER: pelvic floor muscle training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Alcohol and Implicit Process in Sexual Risk Behavior in MSM
Status: COMPLETED
Conditions: Alcohol Drinking|Sex Behavior|Men
Interventions: DRUG: Alcohol|OTHER: Placebo (non-alcoholic beverage)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Gamma-Secretase/Notch Signalling Pathway Inhibitor RO4929097 and Temsirolimus in Treating Patients With Advanced Solid Tumors
Status: COMPLETED
Conditions: Endometrial Papillary Serous Carcinoma|Recurrent Endometrial Carcinoma|Recurrent Renal Cell Cancer|Stage III Endometrial Carcinoma|Stage III Renal Cell Cancer|Stage IV Endometrial Carcinoma|Stage IV Renal Cell Cancer|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: temsirolimus|DRUG: gamma-secretase/Notch signalling pathway inhibitor RO4929097|OTHER: laboratory biomarker analysis|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Physiological Effects of Yogurt With Bb12 in Subjects With GI Symptoms Strointestinal Symptoms
Status: COMPLETED
Conditions: Non-diarrhea Functional Bowel Symptoms
Interventions: OTHER: A probiotic yogurt with inulin|OTHER: Acidified dairy snack
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Study To Evaluate The Efficacy of a Proprietary Mix of Live Probiotics In The Prophylaxis Of Diarrhea In Adult Patients
Status: COMPLETED
Conditions: Diarrhea
Interventions: OTHER: Yovis Capsules|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Lentil-containing Food Products on Satiety and Food Intake
Status: COMPLETED
Conditions: Appetite|Satiety|Food Intake
Interventions: OTHER: Small Green Lentil Muffin|OTHER: Split Red Lentil Muffin|OTHER: Wheat Muffin|OTHER: Small Green Lentil Chili|OTHER: Split Red Lentil Chili|OTHER: Rice Chili
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Dose Confirmation and Pharmacokinetic Study of Pegcrisantaspase Administered as Intravenous (IV) Infusion in Children and Young Adults With Acute Lymphoblastic Leukemia (ALL) /Lymphoblastic Lymphoma (LBL). Following Hypersensitivity to Pegaspargase (Oncaspar)
Status: TERMINATED
Conditions: Acute Lymphoblastic Leukemia|Lymphoblastic Lymphoma
Interventions: DRUG: pegcrisantaspase
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hypertonic Saline and Mucociliary Clearance in Children
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: 0.12% saline|DRUG: 7% saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy Analysis of Anti-VEGF Drugs Combined With Micropulse Laser in the Treatment of Diabetic Macular Edema
Status: RECRUITING
Conditions: Macular Edema Due to Type 2 Diabetes Mellitus
Interventions: DRUG: Anti-VEGF|RADIATION: subthreshold micropulse laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pathways Relating Amnestic MCI to a Mild Traumatic Brain Injury History
Status: RECRUITING
Conditions: Mild Cognitive Impairment|Amnestic Mild Cognitive Disorder|Amnestic Mild Cognitive Impairment|Mild Traumatic Brain Injury|Concussion, Brain
Interventions: DEVICE: High Definition Transcranial Direct Current Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Pharmacokinetics (Drug Levels in Blood) of BMS-986165 When Taken as Various Solid Tablet Prototypes by Healthy Participants
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DRUG: BMS-986165|DRUG: BMS-986165 prototype 1|DRUG: BMS-986165 prototype 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I Dose Escalation Study of SGN-35 Alone and in Combination With Gemcitabine for CD30-Positive Malignancies
Status: TERMINATED
Conditions: Disease, Hodgkin|Lymphoma, Large-Cell, Anaplastic|Lymphoma, Non-Hodgkin
Interventions: DRUG: SGN-35|DRUG: gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Delta Q Value to Discriminate Detrusor Underactivity From Bladder Outlet Obstruction
Status: COMPLETED
Conditions: Urinary Obstruction|Detrusor Underactivity
Interventions: DIAGNOSTIC_TEST: Uroflowmetry
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Investigate the Pharmacokinetics, Efficacy and Safety of INM005 in Patients With COVID-19.
Status: COMPLETED
Conditions: Covid19
Interventions: DRUG: INM005|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ABI-007 (Nab-Paclitaxel) and Gemcitabine in Treating Women With Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Gemcitabine|DRUG: Paclitaxel protein-bound particles for injectable suspension (albumin-bound)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioavailability and Effect of Food on DSM265 Granules in Healthy Adult Subjects
Status: TERMINATED
Conditions: Healthy Volunteers|Bioavailability
Interventions: DRUG: DSM265 50% SDD granules|DRUG: DSM265 25% SDD powder for suspension
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Influence of Physical Therapy for Foot and Ankle in the Gait of Individuals With Diabetic Neuropathy
Status: COMPLETED
Conditions: Diabetic Neuropathy With Loss of Sensation|Foot and Ankle Muscle Weakness|Foot and Ankle Range of Movement Restriction
Interventions: OTHER: Physical Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing Maximal and Half-maximal Suction Pressure Applied During Water Exchange in Colonoscopy
Status: UNKNOWN
Conditions: Minimally Sedated Patient Undergoing Colonoscopy
Interventions: PROCEDURE: half-maximal pressure|PROCEDURE: maximal pressure|DEVICE: Suction Unit
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Effectiveness of Training in Reading Rehabilitation for Patients With Diabetic Macular Oedema
Status: COMPLETED
Conditions: Diabetic Macular Oedema|Parafoveal Scotoma
Interventions: OTHER: Temporal Group|OTHER: Spatial Group|OTHER: Combined Group|OTHER: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: THRIVE+ Pharmacy Liaison-Patient Navigation Intervention
Status: COMPLETED
Conditions: Healthcare Utilization
Interventions: OTHER: THRIVE screening and referral|OTHER: Pharmacy Care Program services|OTHER: Patient Navigation Services|OTHER: Motivational Interviewing|OTHER: Linkage to Community Partner Organization
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Safety, Tolerability, and Efficacy of Selonsertib, Firsocostat, and Cilofexor in Adults With Nonalcoholic Steatohepatitis (NASH)
Status: COMPLETED
Conditions: Nonalcoholic Steatohepatitis (NASH)|Nonalcoholic Fatty Liver Disease (NAFLD)
Interventions: DRUG: SEL|DRUG: FIR|DRUG: CILO|DRUG: FENO|DRUG: VAS
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intraocular Pressure and Hemodialysis Midwestern Brazil
Status: COMPLETED
Conditions: Renal Insufficiency, Chronic|Glaucoma
Interventions: OTHER: Kowa HA-2 Perkins applanation tonometer.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: PET/CT Imaging Study of the Safety and Diagnostic Performance of [68Ga]RM2 in Patients With Primary Prostate Cancer
Status: TERMINATED
Conditions: Prostate Cancer
Interventions: DRUG: [68Ga]RM2|PROCEDURE: PET/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Marched Pair Study Conventional Doxorubicin(DOX) Versus Pegylated Liposomal Doxorubicin(PLD) Neoadjuvant Chemotherapy
Status: UNKNOWN
Conditions: Antineoplastic Combined Chemotherapy Protocols
Interventions: DRUG: Pegylated Liposomal Doxorubicin|DRUG: Cyclophosphamide|DRUG: Taxotere|DRUG: Dexrazoxane (DZR)|DRUG: vitamin B|DRUG: Doxorubicin|PROCEDURE: Breast Conserved Surgery|PROCEDURE: Modified Radical Mastectomy|PROCEDURE: Sentinel Lymph Node Biopsy（SLNB）
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Biomarker-oriented Study of Durvalumab (MEDI4736) in Combination With Olaparib and Paclitaxel in Gastric Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Gastric Cancer
Interventions: DRUG: Paclitaxel|DRUG: Olaparib|DRUG: Durvalumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Quadruple Immunotherapy for Neuroblastoma
Status: RECRUITING
Conditions: Neuroblastoma Recurrent
Interventions: BIOLOGICAL: Natural killer cell|DRUG: Dinutuximab beta|DRUG: Interleukin-2|DRUG: Granulocyte-Macrophage Colony-Stimulating Factor|DRUG: Spironolactone|DRUG: Naxitamab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Assessment of a Daily Wear Monthly Replacement Soft Silicone Hydrogel Contact Lens
Status: COMPLETED
Conditions: Myopia
Interventions: DEVICE: Lehfilcon A contact lenses|DEVICE: Comfilcon A contact lenses|DEVICE: CLEAR CARE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I Study of Immunotherapy With GSC -Loaded Dendritic Cells in Patients With Recurrent Glioblastoma
Status: COMPLETED
Conditions: de Novo Glioblastoma
Interventions: BIOLOGICAL: GSC-loaded autologous dendritic cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Respiratory Muscle Training on Lung Function on Quarry Workers in Minia Government Egypt
Status: COMPLETED
Conditions: Lung Function Decreased
Interventions: PROCEDURE: aerobic exercises with electrical treadmill for 30 min and inspiratory muscle training for 10 minutes.,
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pharmacokinetic Profiles of Inhaled Lipid Complex Amphotericin B (Abelcet ®)
Status: COMPLETED
Conditions: Lung Transplantation|Fungal Infections
Interventions: DRUG: Amphotericin B
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Trial Testing Safety of IL-21 NK Cells for Induction of R/R AML
Status: RECRUITING
Conditions: Allogeneic Stem Cell Transplant Recipient|Blasts 10 Percent or More of Bone Marrow Nucleated Cells|Recurrent Acute Myeloid Leukemia|Refractory Acute Myeloid Leukemia
Interventions: DRUG: Cytarabine Hydrochloride|DRUG: Fludarabine|BIOLOGICAL: Membrane-bound Interleukin-21-Expanded Haploidentical Natural Killer Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Oral Midazolam in Comparison Promethazine With Nitrous Oxide for Uncooperative Children
Status: UNKNOWN
Conditions: Conscious Sedation
Interventions: DRUG: Promethazine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Effects of Non-invasive Neuromodulation on Illness Awareness in Schizophrenia
Status: RECRUITING
Conditions: Schizophrenia|Anosognosia
Interventions: DEVICE: Investigational brainstem neuromodulation device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hematopoietic Stem Cells Transplantation in Children With Combined Immunodeficiency (CID)
Status: TERMINATED
Conditions: Combined Immunodeficiencies
Interventions: BIOLOGICAL: Depletion in CD45RA graft donor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of an Interventional Intervention in Improving the Work Environment of Nurses and Nursing Assistants in the Hospital
Status: RECRUITING
Conditions: Healthy Work Environment|Burnout|Intention to Leave|Engagement
Interventions: BEHAVIORAL: effectiveness of a training course on a healthy work environment for nurses and nursing assistants in a hospital
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Treatment of Myofascial Pain Syndrome With Lidocaine Injection and Physical Therapy.
Status: COMPLETED
Conditions: Myofascial Pain Syndrome|Pain|Myofascial Trigger Point Pain|Musculoskeletal Pain
Interventions: OTHER: Physical therapy|DRUG: Lidocaine injection|OTHER: Lidocaine injection + physical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Pharmacokinetic Characteristics Evaluation on GST-HG121 Tablets
Status: RECRUITING
Conditions: Pharmacokinetics|Food Affect|Single Ascending Dose|Maximum Applicable Dose
Interventions: DRUG: GST-HG121 tablets|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Cortisol and Nutritional Sympathetic Responsiveness
Status: UNKNOWN
Conditions: Metabolic Syndrome|Obesity|Insulin Resistance
Interventions: DRUG: metyrapone|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Extended Clomiphene Citrate Regimen in Women With Polycystic Ovary Syndrome
Status: COMPLETED
Conditions: Infertility
Interventions: DRUG: clomiphene citrate|PROCEDURE: laparoscopic ovarian drilling (LOD)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Analgesic Efficacy of Bilateral US Guided TTPB vs ESPB in Pediatric Patients Undergoing Corrective Cardiac Surgeries
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: PROCEDURE: Erector spinae plane block|PROCEDURE: Transversus thoracis plane block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Auricular Stimulation vs. Expressive Writing for Exam Anxiety
Status: COMPLETED
Conditions: Anxiety
Interventions: DEVICE: Auricular acupuncture|BEHAVIORAL: Expressive writing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial to Learn How Safe Vericiguat (BAY1021189) is and the Way the Body Absorbs, Distributes and Gets Rid of Vericiguat in Participants With Kidney Disease and in Age-, Weight- and Gender-matched Healthy Participants
Status: COMPLETED
Conditions: Heart Failure
Interventions: DRUG: Vericiguat (BAY1021189)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study on MAFLD-related Cirrhosis Prevention and Treatment Strategies
Status: NOT_YET_RECRUITING
Conditions: Metabolic Dysfunction-associated Fatty Liver Disease|Cirrhosis
Interventions: DRUG: Pioglitazone metformin tablets|DRUG: Other drugs|OTHER: Drug-free
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ALK27-001: A Study of Trospium Inhalation Powder (TrIP)Administered to Subjects With COPD
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: DRUG: Placebo|DRUG: TrIP-2D|DRUG: TrIP-2SS|DRUG: TrIP-2D|DRUG: TrIP-2SS + Foradil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: S0002 - A Program to Quit Smoking With or Without Bupropion in Treating Patients With Stage I or II Non-Small Cell Lung Cancer Who Have Undergone Surgery
Status: TERMINATED
Conditions: Lung Cancer
Interventions: BEHAVIORAL: smoking cessation intervention|DRUG: bupropion hydrochloride|DRUG: nicotine|PROCEDURE: psychosocial assessment and care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Trial of 2 Step ATG for Prevention of Acute GVHD Post Allogeneic Stem Cell Transplant
Status: NOT_YET_RECRUITING
Conditions: Acute Leukemia|Myelodysplastic Syndrome|Myeloproliferative Disorders
Interventions: DRUG: ATG dosing platform when combined with standard tacrolimus and mini methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GLP-1 RA on Alcohol Consumption, Metabolism and Liver Parameters in Patients With Obesity and Fatty Liver Disease
Status: NOT_YET_RECRUITING
Conditions: Adiposity|Fatty Liver|Alcohol Use Disorder
Interventions: DRUG: Liraglutide|BEHAVIORAL: Weight reduction recommendations (nutritional and exercise)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Tadalafil on Insulin Secretion and Insulin Sensitivity in Obese Men.
Status: COMPLETED
Conditions: Obesity
Interventions: DRUG: Tadalafil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Validity of Fractional Exhaled Nitric Oxide and Impulse Oscillometry in Patients With Cough Variant Asthma
Status: COMPLETED
Conditions: Cough Variant Asthma
Interventions: DIAGNOSTIC_TEST: fractional exhaled nitric oxide(FeNO)|DIAGNOSTIC_TEST: impulse oscillometry(IOS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Supportive Care for Patients With Hematological Malignancies Undergoing Hematopoietic Cell Transplant
Status: COMPLETED
Conditions: Hematopoietic/Lymphoid Cancer
Interventions: OTHER: palliative care|OTHER: questionnaire administration|PROCEDURE: quality-of-life assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Niraparib With beVAcizumab After Complete cytoreductioN in Patients With ovArian Cancer
Status: RECRUITING
Conditions: Ovarian Cancer
Interventions: DRUG: Chemotherapy|DRUG: Bevacizumab-Awwb|DRUG: Niraparib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Thoracic Spinal Cord Stimulation as a Symptomatic Treatment for Advanced Parkinson's Disease
Status: UNKNOWN
Conditions: Parkinson
Interventions: DEVICE: Kit for Spinal Cord Stimulator System " SCS Systems " : PRECISION® System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Quality Control of CE-Certified Phonak Hearing Aids - 2018_07
Status: COMPLETED
Conditions: Hearing Loss, Sensorineural
Interventions: DEVICE: Extension of Virto B-Titanium|DEVICE: Virto B-Titanium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT