pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Lung Cancer Screening Study With Low-dose CT Scan and Blood Biomarker
Status: COMPLETED
Conditions: High Risk of Developing Lung Cancer
Interventions: RADIATION: CT scan & Early CDT Lung test|OTHER: CT scan & Early CDT Lung test
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Study of Psychopathological Characteristics of Patient Smoking in Thoracic Oncology
Status: COMPLETED
Conditions: Smoking Cessation and Lung Cancer
Interventions: BEHAVIORAL: Research interviews|BEHAVIORAL: Tests (Fagerström, Q-MAT, H.A.D.S, SCL 90-R)|BEHAVIORAL: Projective methods (Thematic apperception Test, Rorschach)|BEHAVIORAL: Carbon monoxide test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Double Lumen Tube Intubation
Status: UNKNOWN
Conditions: Endotracheal Intubation|Cardiac Arrest
Interventions: DEVICE: standard double-lumen tube|DEVICE: VivaSight Double Lumen Tube
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Photodynamic Therapy With Polyhematoporphyrin for Malignant Biliary Obstruction
Status: COMPLETED
Conditions: Klatskin's Tumor
Interventions: PROCEDURE: Photodynamic therapy using polyhematoporphyrin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Golcadomide Post-CAR T-cell in R/R Aggressive Large B-cell Lymphoma Patients With High Risk of Relapse
Status: NOT_YET_RECRUITING
Conditions: Diffuse Large B-cell Lymphoma Refractory|Refractory Primary Mediastinal Large B-Cell Lymphoma|Refractory Transformed B-cell Non-Hodgkin Lymphoma|Refractory High Grade B-Cell Lymphoma
Interventions: DRUG: golcadomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Safety and Immunogenicity Study in Healthy Adults of VAX125, a Recombinant HA-flagellin Influenza Vaccine
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: VAX125
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Enhanced Systemic Combined With Local Treatment for Primary and Metastatic Lesions in Oligo-metastatic Prostate Cancer
Status: UNKNOWN
Conditions: Prostate Cancer
Interventions: DRUG: Leuprolide acetate|DRUG: Goserelin acetate|DRUG: Triptorelin acetate|DRUG: Degarelix acetate|DRUG: Abiraterone acetate|DRUG: Apalutamide|DRUG: Enzalutamide|PROCEDURE: Local treatment for primary lesion|RADIATION: Radiotherapy for primary lesion|RADIATION: Radiotherapy for metastatic lesion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Arsenic Trioxide Contained in TACE in the Treatment of HCC
Status: UNKNOWN
Conditions: Carcinoma, Hepatocellular
Interventions: DRUG: TACE containing As2O3|DRUG: TACE containing placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Open Label Trial of Oral Letermovir for CMV Prophylaxis in Thoracic Transplant Recipients
Status: RECRUITING
Conditions: Cytomegalovirus Infections|Transplant-Related Disorder
Interventions: DRUG: Letermovir 480 MG [Prevymis]
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Prospective, Randomized Trial Comparing Same Day Discharge and Overnight Hospital Stay Among Total Hip Arthroplasties Done by the Direct Anterior Approach
Status: COMPLETED
Conditions: Osteoarthritis of the Hip
Interventions: PROCEDURE: Same day discharge|PROCEDURE: Next day discharge
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose:
Clinical trial: Safety of Cream Containing Sericin and Turmeric in Healthy Volunteers
Status: NOT_YET_RECRUITING
Conditions: Safety Issues
Interventions: OTHER: cream containing 2.5% sericin and 2%turmeric|OTHER: cream containing 5%sericin and 2%turmeric|OTHER: cream containing 10%sericin and 2%turmeric|OTHER: cream base
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Chromosomal Instability in Ovarian Cancer
Status: UNKNOWN
Conditions: Epithelial Ovarian Cancer|High-grade Serous Ovarian Carcinoma|Chromosomal Instability|Somatic Copy Number Distortion|Survival Outcomes|Minimal Residual Lesions|Progression-free Survival|Overall Survival
Interventions: DIAGNOSTIC_TEST: Testing for chromosomal instability (CIN)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase 3 Trial to Evaluate the Safety and Efficacy of Ensifentrine in Patients With COPD
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Ensifentrine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Impact of Gall Bladder Emptying and Bile Acids on the Human GLP-1-secretion
Status: COMPLETED
Conditions: To Assess the Impact of Bile Acids on Human Glukagon-like-peptide-1 Secretion
Interventions: DRUG: Acetaminophen|DRUG: Metformin|DRUG: Colesevelam|OTHER: Cholecystokinin-8|OTHER: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Pharmacokinetic/Pharmacodynamic Study Comparing PF-05280586 To Rituximab In Subjects With Active Rheumatoid Arthritis With An Inadequate Response To TNF Inhibitors (REFLECTIONS B328-01)
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: BIOLOGICAL: PF-05280586|BIOLOGICAL: MabThera|BIOLOGICAL: Rituxan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Letrozole vs Clomiphene Citrate for Induction of Ovulation in Women With Polycystic Ovarian Syndrome
Status: COMPLETED
Conditions: Polycystic Ovary Syndrome|Infertility
Interventions: DRUG: letrozole 2.5mg-7.5mg|DRUG: Clomiphene Citrate 50mg-150mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pancreaticoduodenectomies With Complete Arterial Coverage by Retromesenteric Omentoplasty
Status: NOT_YET_RECRUITING
Conditions: Pancreatectomy|Complication of Surgical Procedure
Interventions: PROCEDURE: Pancreaticoduodenectomy without retromesenteric omental flap|PROCEDURE: Pancreaticoduodenectomy with retromesenteric omental flap
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Sitagliptin on Gastric Emptying in Healthy Subjects
Status: COMPLETED
Conditions: Gastroparesis|Diabetes Mellitus
Interventions: DRUG: Sitagliptin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Orthotopic Liver Transplant (OLT) Recipients With Hepatitis C Virus (HCV) Under Preemptive Treatment
Status: WITHDRAWN
Conditions: Hepatitis C
Interventions: DRUG: Pegylated Interferon|DRUG: Ribavirin|PROCEDURE: Liver Biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Nefopam on Hyperalgesia After Cardiac Surgery
Status: COMPLETED
Conditions: Hyperalgesia|Pain, Postoperative|Pain, Chronic Disease
Interventions: DRUG: Nefopam|DRUG: néfopam|DRUG: Placebo comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Electromuscular Stimulation Therapy as a Prophylactic Method to Reduce Thromboses Related to PICC Catheters in Patients Hospitalized in Critical Care Units.
Status: NOT_YET_RECRUITING
Conditions: Thrombosis; Catheter, Infusion Catheter (Vascular)
Interventions: DEVICE: Protocol ECOEMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Kinectics of Distribution of Doxorubicin-Lipiodol Emulsion in c-TACE
Status: COMPLETED
Conditions: Hepato Cellular Carcinoma
Interventions: DRUG: Super selective transarterial chemoembolization of CHC, with doxorubicin reconstituted in 5cc iso-osmolar ionic iodinated contrast media|DRUG: Super selective transarterial chemoembolization of CHC, with doxorubicin reconstituted in 5cc normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Phenylephrine for Spinal Induced Hypotension
Status: COMPLETED
Conditions: Hypotension
Interventions: DRUG: Phenylephrine bolus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Hemodynamic Effect Between the Spinal Anesthesia and Saddle Block Using Levobupivacaine During Transurethral Resection of the Prostate in Cardiac Elderly Patients
Status: RECRUITING
Conditions: TURP Syndrome|Spinal Anesthesia
Interventions: DRUG: spinal anesthesia|DRUG: saddle block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Multi-centre, Open Label, Single-arm Study Intended to Further Investigate the Safety and Efficacy of Plerixafor as a Front-line Mobilisation Agent in Combination With G-CSF in Patients With Lymphoma or MM (Multiple Myeloma).
Status: COMPLETED
Conditions: Lymphoma (Non-Hodgkin's Lymphoma)|Hodgkin's Disease or Multiple Myeloma|Front Line Mobilization|Transplantation
Interventions: DRUG: Generic = Plerixafor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efferent Loop Stimulation Previous to Ileostomy Closure. Ileostim Trial.
Status: UNKNOWN
Conditions: Ileostomy - Stoma|Ileus|Rectal Cancer|Surgical Complication
Interventions: OTHER: Ileostomy stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Histologic Assessment of the Difference Between 18F-2-fluoro-2-deoxy_D-glucose Positron Emission Mammography(PEM) and Magnetic Resonance Imaging (MRI) of the Breast
Status: TERMINATED
Conditions: Breast Cancer
Interventions: DEVICE: Positron Emission Mammography (PEM) and Magnetic Resonance Imaging (MRI)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Pembrolizumab and Cryosurgery in Treating Patients With Newly Diagnosed, Oligo-metastatic Prostate Cancer
Status: COMPLETED
Conditions: Stage IV Prostate Cancer
Interventions: PROCEDURE: Cryosurgery|DRUG: Degarelix|OTHER: Laboratory Biomarker Analysis|BIOLOGICAL: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Duvelisib in Patients With Relapsed or Refractory Peripheral T-cell Lymphoma (PTCL)
Status: COMPLETED
Conditions: Peripheral T-cell Lymphoma
Interventions: DRUG: Duvelisib|DRUG: Duvelisib|DRUG: Duvelisib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oxytocin for Hypermobile Ehlers-Danlos Syndrome
Status: RECRUITING
Conditions: Hypermobile Ehlers-Danlos Syndrome|Pain Assessment
Interventions: DRUG: Oxytocin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety and Effectiveness Evaluation of Two Kinds of Peritoneal Dialysate
Status: COMPLETED
Conditions: Kidney Failure,Chronic
Interventions: DRUG: Huaren Peritoneal Dialysate|DRUG: Baxter Peritoneal Dialysate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Physiological Effects of Human Ether-a-go-go-Related Gene (hERG)Blockade on Metabolism
Status: COMPLETED
Conditions: Long QT Syndrome|Hypoglycemia
Interventions: DRUG: Moxifloxacin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Human vs Machine: a RCT Comparing Traditional In-person Instruction, AI Versus VR for Learning Basic CCE
Status: RECRUITING
Conditions: Ultrasound
Interventions: OTHER: AI enabled ultrasound system for self-directed learning|OTHER: Simulator for self-directed learning|OTHER: traditional with human instructors
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Efficacy and Safety of Fexinidazole in Patients With Stage 1 or Early Stage 2 Human African Trypanosomiasis (HAT) Due to T.b. Gambiense: a Prospective, Multicentre, Open-label Cohort Study, plug-in to the Pivotal Study
Status: COMPLETED
Conditions: Human African Trypanosomiasis (HAT)
Interventions: DRUG: Fexinidazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Supplementary Motor Area is a Potential Target for Speech Disturbance in Parkinson Disease
Status: NOT_YET_RECRUITING
Conditions: Parkinson Disease
Interventions: DEVICE: "MAGSTIM" Repetitive transcranial magnetic stimulator (rTMS) system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Phase IIa Proof-of-concept Study of NC-503 in Patients With Type II Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Metabolic Syndrome X
Interventions: DRUG: NC-503 (eprodisate disodium)|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cellular Therapy With Cord Blood Cells
Status: COMPLETED
Conditions: Multiple Myeloma|Leukemia|Lymphoma
Interventions: DRUG: Fludarabine|DRUG: Melphalan|PROCEDURE: Umbilical Cord Blood|DRUG: Rituximab|OTHER: Peripheral Blood Stem Cell Infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Daptomycin Given During Dialysis and After Dialysis
Status: COMPLETED
Conditions: End-stage Renal Disease|Renal Failure Chronic Requiring Hemodialysis
Interventions: DRUG: daptomycin|DRUG: daptomycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Ustekinumab in Pediatric Participants With Moderately to Severely Active Crohn's Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Crohn Disease
Interventions: DRUG: Ustekinumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Diets, Lipoproteins and Inflammation Markers
Status: COMPLETED
Conditions: Cardiovascular Diseases|Metabolic Syndrome|Diet, Healthy|Vegan Diet|Inflammatory Response
Interventions: BEHAVIORAL: Vegan diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Exercise and Nutritional Rehabilitation in Patients With Cancer
Status: COMPLETED
Conditions: Cachexia; Cancer|Diet Modification|Physical Activity|Advanced Cancer
Interventions: DIETARY_SUPPLEMENT: ProSure|BEHAVIORAL: Physical Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Fresh Autologous Whole Blood Transfusion After Cardiopulmonary Bypass
Status: RECRUITING
Conditions: Cardiac Disease|Bleeding Postoperative
Interventions: OTHER: Fresh Autologous whole Blood|OTHER: Standard of Care Expectant management of bleeding
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Local Application of Autologous Bone Marrow Cells for Treatment of Chronic Diabetic Ulcers
Status: UNKNOWN
Conditions: Diabetic Foot|Diabetes Complications
Interventions: PROCEDURE: Application of autologous bone marrow
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Electrical Stimulation for Preventing Loss of Muscle Mass in Patients With Sepsis
Status: RECRUITING
Conditions: Sepsis|Septic Shock
Interventions: PROCEDURE: Experimental Electrical Stimulation|PROCEDURE: Sham Electrical Stimulation|OTHER: Conventional Physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: HIPP Learning to Live Better With Lupus: The Health Improvement and Prevention Program in Systemic Lupus Erythematosus
Status: UNKNOWN
Conditions: Systemic Lupus Erythematosus
Interventions: BEHAVIORAL: Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Insulin Pump Therapy and Continuous Glucose Monitoring in Diabetic Continuous Ambulatory Peritoneal Dialysis (CAPD) Patients
Status: UNKNOWN
Conditions: Diabetes|Poor Glycemic Control
Interventions: PROCEDURE: CSII and MDI
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Docetaxel and Loplatin Induction Chemotherapy Followed by Concurrent Chemoradiotherapy for Locally Advanced SCCHN
Status: UNKNOWN
Conditions: Locally Advanced Head and Neck Squamous Cell Carcinoma
Interventions: DRUG: Lobaplatin|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Outpatient Management of Patients With Exacerbation of Chronic Obstructive Pulmonary Disease
Status: UNKNOWN
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: PROCEDURE: Patient education and disease management
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: ECT
Clinical trial: A Phase 1 Study of NOV1601(CHC2014) in Adult Subjects With Solid Organ Malignancies
Status: COMPLETED
Conditions: Phase 1|Solid Tumor, Adult
Interventions: DRUG: NOV1601(CHC2014)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial of IW-3718 for 8 Weeks in Patients With Symptomatic Gastroesophageal Reflux Disease (GERD)
Status: COMPLETED
Conditions: Gastroesophageal Reflux Disease
Interventions: DRUG: IW-3718|DRUG: Matching Placebo|DRUG: PPI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An Open-Label Extension Study of NGX-4010 for the Treatment of Neuropathic Pain
Status: TERMINATED
Conditions: Herpes Zoster|Neuralgia|Pain|HIV Infections|Peripheral Nervous System Diseases|Diabetic Neuropathies|Diabetes Mellitus|Polyneuropathies
Interventions: DRUG: Capsaicin Dermal Patch
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Divalproex Sodium vs. Placebo in Childhood/Adolescent Autism
Status: COMPLETED
Conditions: Autism
Interventions: DRUG: Divalproex sodium|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Angiolite Stent vs a Second-generation Drug-eluting Stent Xience for Percutaneous Coronary Intervention
Status: COMPLETED
Conditions: Coronary Artery Disease|Drug-eluting Stent
Interventions: DEVICE: Angiolite|DEVICE: Xience
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Sleeping For Two: Trial for CBT for Insomnia in Pregnancy
Status: COMPLETED
Conditions: Insomnia|Sleep Disturbance
Interventions: BEHAVIORAL: Cognitive Behavioural Therapy for Insomnia|OTHER: Active Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dose Response of Fractional Exhaled Nitric Oxide (FeNO) to Inhaled Steroids in Mild-to-moderate Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Fluticasone Propionate|DRUG: Fluticasone Propionate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Wellbeing in Pregnancy: Evaluating an Intervention to Improve Women's Emotional Wellbeing in Pregnancy
Status: COMPLETED
Conditions: Peripartum Period|Mental Health|Pregnant Women
Interventions: OTHER: Wellbeing Plan|OTHER: Control task
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: Study of the Mechanisms of Metabolic Adaptations to Overfeeding
Status: UNKNOWN
Conditions: Obesity|Diabetes
Interventions: OTHER: Hypercaloric diet|DIETARY_SUPPLEMENT: polyphenols|DIETARY_SUPPLEMENT: placebo (for polyphenols)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Phase Ia Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Subcutaneously Administered CUG252 in Normal Healthy Volunteers
Status: ACTIVE_NOT_RECRUITING
Conditions: Systemic Lupus Erythematosus
Interventions: DRUG: CUG252|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bupivacaine Liposomal Injectable Suspension, Pain and Narcotic Use After Elective Orthognathic Surgery
Status: WITHDRAWN
Conditions: Orthognathic Surgery
Interventions: DRUG: Bupivacaine Extended Release Liposome Injection|DRUG: Bupivacaine HCl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Biofeedback for Dyssynergic Constipation
Status: COMPLETED
Conditions: Constipation
Interventions: BEHAVIORAL: Biofeedback|DRUG: Diazepam|BEHAVIORAL: Pelvic floor retraining
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Naloxone for the Treatment of Opioid-Induced Pruritus
Status: COMPLETED
Conditions: Pruritus
Interventions: DRUG: Naloxone|DRUG: Saline/Morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Regional Anesthesia on Enhanced Recovery After Spine Surgeries
Status: COMPLETED
Conditions: ERAS
Interventions: PROCEDURE: Erector spinae plane block|PROCEDURE: Throacolumbar interfacial plane block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study Comparing the Efficacy of Two Ibuprofen Formulations
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: placebo|DRUG: ibuprofen Formulation 1|DRUG: ibuprofen Formulation 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: CEB-01 in Locally Resectable Pancreatic Cancer
Status: RECRUITING
Conditions: Pancreatic Carcinoma
Interventions: PROCEDURE: Standard surgery|DRUG: CEB-01
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility of Mindfulness Meditation Training and Home Practice in Persons With Spinal Cord Injury
Status: ACTIVE_NOT_RECRUITING
Conditions: Spinal Cord Injuries
Interventions: OTHER: mindfulness meditation(MM)|OTHER: Health Education (active control)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Access to PrEP for MSM: Acceptability and Feasibility in Community-based Clinics in West Africa (CohMSM-PrEP)
Status: COMPLETED
Conditions: HIV/AIDS
Interventions: DRUG: HIV prevention package including PrEP
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effect of Education Based on the Chronic Care Model in COPD Patients
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive|Lung Diseases, Obstructive|Self-Management|Nursing Care
Interventions: BEHAVIORAL: Education and telephone follow ups based on the Chronic Care Model
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of CSF-3 in Performing ECG
Status: COMPLETED
Conditions: Healthy|ECG
Interventions: DEVICE: CSF-3 watch, designed to monitor a user's heart rate based on ECG (electrocardiogram) and PPG (Photoplethysmograph) readings
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Bilateral External Oblique İntercostal (EOI) Plane Block in Patients Undergoing Laparoscopic Cholecystectomy.
Status: COMPLETED
Conditions: Laparoscopic Cholecystectomy
Interventions: OTHER: Bilateral External Oblique İntercostal (EOI) Plane Block|OTHER: Standard perioperative and postoperative multimodal analgesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Animation Education Program Applied to Laparoscopic Sleeve Gastrectomy Patients
Status: COMPLETED
Conditions: Surgery|Educational Problems
Interventions: BEHAVIORAL: Animation Education Program Applied to Laparoscopic Sleeve Gastrectomy Patients
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Retest-reliability and At-home-assessment Feasibility of the 5R-STS
Status: COMPLETED
Conditions: Degenerative Disc Disease|Spondylolisthesis|Spondylosis|Herniated Nucleus Pulposus|Spinal Stenosis Lumbar|Spinal Diseases|Spinal Instability
Interventions: DIAGNOSTIC_TEST: five-repetition sit-to-stand test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The IM-ZBULLE Study : " Z-track " and " Airlock " Techniques During Intramuscular Injection of Haloperidol Decanoate
Status: NOT_YET_RECRUITING
Conditions: Schizophrenia; Psychosis
Interventions: OTHER: Intramuscular injection of Haloperidol decanoate using the "Z-track" and "Airlock" techniques|OTHER: Intramuscular injection of Haloperidol decanoate using standard techniques
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: RCT for Transvaginal Self-cut Mesh vs Mesh-kit for Severe POP
Status: UNKNOWN
Conditions: Pelvic Organ Prolapse
Interventions: PROCEDURE: pelvic floor reconstructive surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Buspirone Maintenance on the Reinforcing Effects of Cocaine
Status: COMPLETED
Conditions: Cocaine Use Disorders
Interventions: DRUG: Buspirone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Mindful Movement and Breathing to Improve Outcomes of Gynecologic Surgery
Status: COMPLETED
Conditions: Gynecologic Malignancy|Abdominal Surgery by Laparotomy|Pain|Psychological Distress|Lung Function|Surgical Complications
Interventions: OTHER: Mindful Movement and Breathing program|OTHER: Questionnaire administration|PROCEDURE: The Observer Mobility Scale|PROCEDURE: Volumetric Incentive Spirometry
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Feasibility and Safety of Head-up Cardiopulmonary Resuscitation in Patients With Non-traumatic Cardiac Arrest
Status: RECRUITING
Conditions: Cardiac Arrest
Interventions: DEVICE: Head-up Cardiopulmonary Resuscitation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Muscle Energy Technique Versus Aerobic Exercises on Pain and Disability in Patients With Chronic Pelvic Pain
Status: COMPLETED
Conditions: Pelvic Pain|Chronic Pain
Interventions: OTHER: Muscle Energy Technique|OTHER: Aerobic Exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Early Rising PSA Endocrine Treatment Versus Chemo-endocrine Therapy- SPCG14
Status: UNKNOWN
Conditions: Prostatic Neoplasms
Interventions: DRUG: Antiandrogen|DRUG: Antiandrogen+docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Two Regimens, With Healthy Male and Female Babies, Ages 3-6 Months Old, Using Various Assessments.
Status: COMPLETED
Conditions: Microbiome
Interventions: OTHER: Cleanser|OTHER: Cleanser and Lotion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Benefit of Changing Chemoradiotherapy Sequence and Modifying Radiotherapy Schedule for Advanced Nasopharyngeal Cancer
Status: UNKNOWN
Conditions: Nasopharyngeal Neoplasms
Interventions: PROCEDURE: Conventional Radiotherapy|PROCEDURE: Accelerated Radiotherapy|DRUG: Cisplatin|DRUG: 5-fluorouracil|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Priming Effects by PLAI Vaccine on the Subsequent Response to Inactivated H5N1 Vaccine
Status: COMPLETED
Conditions: Avian Influenza
Interventions: BIOLOGICAL: OrniFlu® inactivated vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effect of Airway and Chest Wall Oscillation on Respiratory Functions in COPD Patients in Acute Exacerbation
Status: RECRUITING
Conditions: COPD Exacerbation Acute
Interventions: OTHER: CONTROL|DEVICE: PEP DEVICE|DEVICE: HFCWO DEVICE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Safety and Efficacy of SGLT2 Inhibitors in Pre-diabetic Patients
Status: NOT_YET_RECRUITING
Conditions: Prediabetic State|Impaired Fasting Glucose|Impaired Glucose Tolerance
Interventions: DRUG: Dapagliflozin 10mg Tab|BEHAVIORAL: lifestyle interventions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Naltrexone Neuroimaging in Teens With Eating Disorders
Status: RECRUITING
Conditions: Eating Disorders|Binge Eating|Purging (Eating Disorders)|Bulimia Nervosa|Anorexia Nervosa, Atypical
Interventions: DRUG: Naltrexone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: The Feasibility and Clinical Efficacy of Atezolizumab Consolidation Treatment in High Risk (IPI > 2) DLBCL
Status: ACTIVE_NOT_RECRUITING
Conditions: NHL|DLBCL
Interventions: DRUG: Atezolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Intrathecal Morphine, Dexmedetomidine or Both in Combination to Bupivacaine on Immunity
Status: UNKNOWN
Conditions: Immune System Suppression
Interventions: DRUG: Morphine Sulfate|DRUG: Dexmedetomidine|DRUG: Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study to Evaluate Symbicort Turbuhaler Used 'as Needed' in Adults and Adolescents With Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: budesonide/formoterol 'as needed' + budesonide placebo bid|DRUG: budesonode bid + terbutaline 'as needed'
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: LILRB4 STAR-T Cells in the Treatment of Relapsed/Refractory Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Relapsed/Refractory Acute Myeloid Leukemia
Interventions: BIOLOGICAL: LILRB4 STAR-T
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Multiple Doses of AZD6280 on the Pharmacokinetics of Midazolam (CYP3A4) and Caffeine (CYP1A2)
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: AZD6280|DRUG: Midazolam|DRUG: Caffeine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Combination Therapy: Hyperbaric Oxygen and PENTOCLO for Treatment of Osteoradionecrosis of the Mandible
Status: NOT_YET_RECRUITING
Conditions: Osteoradionecrosis|Osteoradionecrosis of Jaw|Osteoradionecrosis of the Mandible
Interventions: DRUG: modified PENTOCLO (mPENTOCLO)|DRUG: sham mPENTOCLO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lidocaine Infusion in Radical Cystectomy
Status: COMPLETED
Conditions: Postoperative Ileus
Interventions: DRUG: Lidocaine|DRUG: IV normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: LY3214996 +/- HCQ in Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Cancer|Advanced Cancer
Interventions: DRUG: Hydroxychloroquine Sulfate|DRUG: LY3214996
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Dexmedetomidine Infusion on Post-operative Cognitive Function and Oxidative Stress in Cardiac Surgery
Status: COMPLETED
Conditions: Oxidative Stress|Cognition Disorders
Interventions: DRUG: Dexmedetomidine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Relationship and Central Mechanism Between Diabetes and Cognitive Impairment Based on Simultaneous EEG-fMRI Approach and Peripheral Neuropathology Biomarkers Assay
Status: RECRUITING
Conditions: Type 2 Diabetes|Alzheimer Disease|Cognitive Impairment
Interventions: BEHAVIORAL: Cognitive assessments|OTHER: Simultaneous EEG-fMRI scan|OTHER: Multimodal magnetic resonance imaging|OTHER: Peripheral blood neuropathology biomarkers assay
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Comparison of Coated and Uncoated Stents in Renal Artery Treatment.
Status: COMPLETED
Conditions: Renal Artery Stenosis
Interventions: DEVICE: Sirolimus-eluting Palmaz Genesis peripheral stent
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Zolmitriptan by Sublingual Administration
Status: UNKNOWN
Conditions: Cluster Headache
Interventions: DRUG: zolmitriptan by sublingual administration|DRUG: zolmitriptan by oral
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Preventive Effect of Different Doses of Intranasal Insulin on Postoperative Delirium
Status: COMPLETED
Conditions: Postoperative Delirium
Interventions: DRUG: Intranasal normal saline|DRUG: Intranasal insulin-20U|DRUG: Intranasal insulin-40U
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Use of NGAL for Fluid Dosing and CRRT Initiation in Pediatric and Neonatal AKI
Status: NOT_YET_RECRUITING
Conditions: Acute Kidney Injury|Acute Kidney Injury Due to Sepsis|Neonatal Sepsis
Interventions: OTHER: Renal Angina Index (RAI)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Safety Study of ABT-263 in Combination With Gemzar (Gemcitabine) in Subjects With Solid Tumors
Status: COMPLETED
Conditions: Solid Tumors
Interventions: DRUG: ABT-263|DRUG: gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevention of Post-STEMI Left Ventricular Thrombus With Optimized Anticoagulant (EARLYmyo-LVT Ⅱ)
Status: UNKNOWN
Conditions: ST Segment Elevation Myocardial Infarction|Left Ventricular Thrombus
Interventions: DRUG: Rivaroxaban
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: LBBP as Initial Therapy in Patients With Non-ischemic Heart Failure and LBBB
Status: RECRUITING
Conditions: Non-ischemic Cardiomyopathy|Heart Failure|Left Bundle-Branch Block
Interventions: DRUG: Guideline-Directed Medical Therapy(GDMT)|COMBINATION_PRODUCT: left bundle branch pacing combined with Guideline-Directed Medical Therapy(LBBP+GDMT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, and Efficacy of Immunomodulation With AT-1501 in Combination With Transplanted Islet Cells in Adults With Brittle T1D
Status: WITHDRAWN
Conditions: Brittle Type 1 Diabetes Mellitus
Interventions: BIOLOGICAL: AT-1501 IV Infusion|BIOLOGICAL: Isolated cadaveric islet cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non-contrast Lung Perfusion Mapping Applied for New Insights in Cystic Fibrosis
Status: ACTIVE_NOT_RECRUITING
Conditions: Cystic Fibrosis
Interventions: DRUG: Initiation of CFTR Modulator|DRUG: Hyperpolarized Xenon 129
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Addition of Silver Nanoparticles to a Orthodontic Primer in Preventing Enamel Demineralization Adjacent Brackets
Status: UNKNOWN
Conditions: Tooth Demineralization
Interventions: OTHER: Silver nanoparticles|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of Tenalisib (RP6530) in Patients With Relapsed/Refractory Chronic Lymphocytic Leukemia (CLL)
Status: COMPLETED
Conditions: Leukemia, Lymphocytic, Chronic, B-Cell
Interventions: DRUG: Tenalisib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Short, Animated Storytelling Video to Increase Knowledge About Sodium Intake as a Cardiovascular Risk Factor
Status: NOT_YET_RECRUITING
Conditions: Sodium Excess|Cardiovascular Risk Factor|Education Entertainment Intervention|Short, Animated Storytelling
Interventions: OTHER: A short, animated storytelling video on dietary sodium|OTHER: A short, animated storytelling attention placebo video
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Prevention of Thromboembolism Using Apixaban vs Enoxaparin Following Spinal Cord Injury
Status: RECRUITING
Conditions: Spinal Cord Injuries|Spinal Diseases
Interventions: DRUG: Apixaban|DRUG: Enoxaparin Sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: CO2 Laser and Open Surgery for T1N0 Glottic SCC With Anterior Commissure Involved
Status: UNKNOWN
Conditions: Squamous Cell Carcinoma of Glottis
Interventions: PROCEDURE: CO2 Laser surgery|PROCEDURE: Open Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Relation of High Sensitivity C Reactive Protein and Total Leucocytic Count Levels in Threatened Abortion
Status: NOT_YET_RECRUITING
Conditions: Abortion Early
Interventions: DIAGNOSTIC_TEST: maternal serum C reactive protein|DIAGNOSTIC_TEST: total leucocytic count levels|DIAGNOSTIC_TEST: differential leucocytic count levels
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Evaluate the Effects of YM872 on Brain Function and Disability When Administered in Combination With Alteplase (Tissue Plasminogen Activator)
Status: COMPLETED
Conditions: Acute Ischemic Stroke
Interventions: DRUG: YM872 (zonampanel), t-PA (alteplase)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Drug Levels of BMS-986166 in Healthy Male Participants
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DRUG: BMS-986166|DRUG: Bisacodyl
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Psychosocial Rehabilitation After Moral Injury and Loss With Adaptive Disclosure
Status: COMPLETED
Conditions: Post-traumatic Stress Disorder|Moral Injury|Traumatic Loss
Interventions: BEHAVIORAL: Adaptive Disclosure for Moral Injury and Loss|BEHAVIORAL: Present Centered Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Use of Selective Estrogen Receptor Modulators in the Treatment of Schizophrenia- a Pilot Study
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder|Schizophreniform Disorder
Interventions: DRUG: Raloxifene|DRUG: Estradiol/dyhydroprogestrone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Oral Bevacizumab-800CW and Cetuximab-800CW Administration to Detect Early Esophageal Adenocarcinomas
Status: NOT_YET_RECRUITING
Conditions: Barrett's Esophagus Without Dysplasia|Barrett Oesophagitis With Dysplasia|Esophageal Adenocarcinoma
Interventions: DRUG: Avastin|DRUG: Erbitux|DEVICE: Fluorescence endoscopy and multi-diameter single fiber reflectance/single fiber fluorescence (MDSFR/SFF) spectroscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Droperidol and Cardiac Repolarization
Status: COMPLETED
Conditions: Cardiac Repolarization
Interventions: DRUG: Xomolix 0.625 mg intravenously|DRUG: Xomolix 1.25 mg|DRUG: Zofran 8 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Electroacupuncture for the Treatment of Agitated Symptoms of Alzheimer's Disease
Status: NOT_YET_RECRUITING
Conditions: Agitation Associated With Alzheimer's Dementia|Alzheimer's Dementia
Interventions: OTHER: Electroacupuncture group|OTHER: Micro-acupuncture group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect on Primary Dysmenorrhea
Status: COMPLETED
Conditions: Primary Dysmenorrhea
Interventions: DRUG: Estradiol valerate, Dienogest (Natazia, Qlaira, BAY86-5027)|DRUG: Ethinyl estradiol, Levonorgestrel (Miranova)|DRUG: Placebo Match to SH T00658ID|DRUG: Placebo Match to SH D593B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Muscle Protein Synthetic Response of Algal and Fungal Protein
Status: COMPLETED
Conditions: Muscle Metabolism
Interventions: DIETARY_SUPPLEMENT: Protein ingestion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE