pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Safety and Pharmacokinetics Study of a Modified Tafasitamab IV Dosing Regimen Combined With Lenalidomide in R-R DLBCL Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Diffuse Large B Cell Lymphoma
Interventions: DRUG: Tafasitamab|DRUG: Lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Serum Vascular Endothelial Growth Factor in Infants With Intravitreal Ranibizumab
Status: COMPLETED
Conditions: Infant, Premature, Diseases
Interventions: DRUG: intravitreal ranibizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Safety and Efficacy of Everolimus Treatment in Liver Transplantation for Liver Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Carcinoma, Hepatocellular
Interventions: DRUG: Everolimus|DRUG: Tacrolimus|DRUG: Myfortic|DRUG: CellCept|DRUG: Imuran
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effectiveness of Extending the "Passerelle" System for Prescribing Adapted Physical Activity to Patients With Type 2 Diabetes in Nouvelle-AQUItaine (France)
Status: NOT_YET_RECRUITING
Conditions: Diabetes Mellitus, Type 2
Interventions: OTHER: Adapted physical activity for 12 months|OTHER: Adapted physical activity for 6 months
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Clinical Study of Recombinant Human Coagulation Factor VIII for Injection in Patients With Severe Hemophilia A
Status: NOT_YET_RECRUITING
Conditions: Hemophilia A
Interventions: DRUG: Recombinant human activated coagulation factor VIII for injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study Examining Use of an Over-the-Counter Supplement for the Prevention of Menstrually-Associated Migraine Headache
Status: COMPLETED
Conditions: Migraine Headache
Interventions: DRUG: Soy Isoflavones
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Intensive Statin Treatment in Acute Ischemic Stroke Patients With INtracranial Atherosclerosis
Status: UNKNOWN
Conditions: Stroke|Intracranial Atherosclerosis
Interventions: DRUG: High-dose statin: Atorvastatin 40mg or Rosuvastatin 20mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Caffeine and L-theanine Both Alone and in Combination on Cerebral Blood Flow, Cognition and Mood
Status: COMPLETED
Conditions: Cognitive Function|Mood
Interventions: DIETARY_SUPPLEMENT: Caffeine and L-theanine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Influence of Decision Aids on the Choice of Mother-infant Rooming-in or Separation Care for Pregnant Women
Status: COMPLETED
Conditions: Pregnancy Related
Interventions: OTHER: Decision aid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Watchful Waiting of Incisional Hernias
Status: COMPLETED
Conditions: Incisional Hernia|Ventral Hernia|Umbilical Hernia
Interventions: BEHAVIORAL: smoking cessation|BEHAVIORAL: tighter diabetic control|BEHAVIORAL: diet and exercise program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exploring the Impact of Two-week Kava on the Metabolism of Nicotine and NNK
Status: WITHDRAWN
Conditions: Kava on the Metabolism of Nicotine and NNK
Interventions: DRUG: Kava
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Guadecitabine in Combination With Carboplatin in Extensive Stage Small Cell Lung Cancer
Status: COMPLETED
Conditions: Small Cell Lung Cancer|Extensive-stage Small Cell Lung Cancer
Interventions: DRUG: Guadecitabine|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Soybean Peptides Product on Regulation of Blood Pressure Effect in Humans
Status: COMPLETED
Conditions: Hypertension
Interventions: DIETARY_SUPPLEMENT: Soybean peptides|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Diagnosis and Treatment of CAD in Severe PAD After Lower Extremity Revascularization
Status: NOT_YET_RECRUITING
Conditions: Peripheral Artery Disease|Coronary Artery Disease
Interventions: DIAGNOSTIC_TEST: Coronary computed topography (CT) angiography with FFR-CT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Characterization of Wild Blueberry Polyphenols Bioavailability and Kinetic Profile Over 24-hour Period
Status: COMPLETED
Conditions: Overweight|Obese|Healthy
Interventions: DIETARY_SUPPLEMENT: Active Comparator|DIETARY_SUPPLEMENT: Placebo Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Spironolactone Therapy In Young Women With NASH
Status: COMPLETED
Conditions: NASH - Nonalcoholic Steatohepatitis
Interventions: DRUG: Spironolactone 100mg|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Immunotherapy After Surgery in Treating Patients With Breast Cancer, Colon Cancer, or Melanoma
Status: UNKNOWN
Conditions: Breast Cancer|Colorectal Cancer|Melanoma (Skin)
Interventions: BIOLOGICAL: Corynebacterium granulosum P40|PROCEDURE: adjuvant therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Pediatric ACTION3 (Identify, Treat, Control): Effectiveness of Adding Montelukast in Pediatric Subjects With Uncontrolled Asthma (0476-385)
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: montelukast sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multi-site Study of Autologous Cord Blood Cells for Hypoxic Ischemic Encephalopathy
Status: COMPLETED
Conditions: Moderate or Severe Hypoxic-ischemic Encephalopathy in Newborns
Interventions: BIOLOGICAL: Infusion of autologous cord blood|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Extracorporeal Photopheresis to Maintain Symptoms Remission During Steroid Withdrawal in Patients With Steroid-Dependent Crohn's Disease
Status: COMPLETED
Conditions: Crohn Disease
Interventions: DRUG: UVADEX and UVAR XTS Photopheresis System
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Targeted Food Elimination for Treatment of Functional Gastrointestinal Diseases in Children
Status: COMPLETED
Conditions: Functional Gastrointestinal Disorders|Functional Abdominal Pain Syndrome|Abdominal Pain (AP)
Interventions: OTHER: Dietary Exclusion|OTHER: Standard Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of GSK1278863A on Pulmonary Artery Pressure in Healthy Volunteers
Status: COMPLETED
Conditions: Anaemia
Interventions: DRUG: GSK1278863|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Protective Effect of Lipo-PGE1 on Myocardial Injury Following Percutaneous Coronary Intervention
Status: UNKNOWN
Conditions: Prostaglandin E1|Percutaneous Coronary Intervention
Interventions: DRUG: lipo-PGE1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Evaluate the Efficacy and Safety of 'DW1601' in Acute Bronchitis
Status: UNKNOWN
Conditions: Acute Bronchitis
Interventions: DRUG: DW1601|DRUG: DW16011|DRUG: DW16012
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of a Digital Patient Platform (CMyLife) for Patients With Chronic Myeloid Leukemia (CML) on Information Provision, Patient Empowerment, Medication Compliance, Guideline Adherence and Quality of Life
Status: COMPLETED
Conditions: Neoplasms|Chronic Myeloid Leukemia|Patient Portals|Telemedicine
Interventions: OTHER: CMyLife
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Trial Comparing the Effects of Xyrem (Sodium Oxybate) With Placebo for the Treatment of Fibromyalgia
Status: COMPLETED
Conditions: Fibromyalgia
Interventions: DRUG: Xyrem (sodium oxybate) oral solution|DRUG: Xyrem (sodium oxybate) oral solution|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: IVIG in Acute Ischemic Stroke: A Pilot Study
Status: WITHDRAWN
Conditions: Ischemic Stroke
Interventions: BIOLOGICAL: Privigen|OTHER: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Examine the Pharmacokinetics, Safety and Tolerability of Multiple Oral Doses of TMC435 in Healthy Chinese Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: TMC435 100 mg|DRUG: TMC435 150 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Equivalence of Budesonide HFA MDI Versus Budesonide Turbuhaler in Mild to Moderate Chinese Asthma Patients
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Budesonide 200 microgram/Puff, HFA MDI|DRUG: Budesonide 100 microgram/Actuation Powder for Inhalation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating the Efficacy and Safety of Giredestrant Compared With Physician's Choice of Endocrine Monotherapy in Participants With Previously Treated Estrogen Receptor-Positive, HER2-Negative Locally Advanced or Metastatic Breast Cancer (acelERA Breast Cancer)
Status: ACTIVE_NOT_RECRUITING
Conditions: Estrogen Receptor-Positive, HER2-Negative, Locally Advanced or Metastatic Breast Cancer
Interventions: DRUG: Giredestrant|DRUG: Fulvestrant or an Aromatase Inhibitor (Physician Choice)|DRUG: LHRH Agonist
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effects of D-1553 on PK of Midazolam, Caffeine, Rosuvastatin, Furosemide, Digoxin, and Itraconazole or Omeprazole on PK of D-1553
Status: ACTIVE_NOT_RECRUITING
Conditions: Healthy Male
Interventions: DRUG: D-1553
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Safety and Efficiency Study of Loading Dose Atorvastatin in Cardiac Surgery
Status: COMPLETED
Conditions: Acute Kidney Injury
Interventions: DRUG: Atorvastatin(Lipitor)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of an Innovative Information, Training and Social Support Intervention "INFOSADEM" to Principal Caregivers of Dementia Patients Living at Home
Status: COMPLETED
Conditions: Dementia
Interventions: OTHER: INFOSA-DEM
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of Weekly Ixabepilone With or Without Biweekly Bevacizumab
Status: COMPLETED
Conditions: Epithelial Ovarian Cancer|Fallopian Tube Cancer|Primary Peritoneal Cancer
Interventions: DRUG: Ixabepilone|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Semi-rigid Shell Barrier System for Alveolar Bone Augmentation (SSBS for ABA)
Status: RECRUITING
Conditions: Guided Bone Regeneration|Bone Formation|Bone Volume
Interventions: PROCEDURE: Ridge augmentation with semi-rigid shell barrier system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Studying Breast Cancer Risk in Women Who Are BRCA1/BRCA2 Mutation Carriers
Status: UNKNOWN
Conditions: brca1 Mutation Carrier|brca2 Mutation Carrier|Breast Cancer
Interventions: GENETIC: DNA analysis|GENETIC: mutation analysis|GENETIC: polymorphism analysis|OTHER: laboratory biomarker analysis|PROCEDURE: evaluation of cancer risk factors
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Exploratory Pharmacokinetic and Bioavailability Study of 2 Capsule Formulations of Torezolid Phosphate
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: TR-701 di-sodium phosphate salt|DRUG: TR-701 free acid phosphate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Safety and Efficacy of Transanal Irrigation in Patients With Sleep Disturbance From Low Anterior Resection Syndrome After Rectal Cancer Surgery (TraLARS)
Status: RECRUITING
Conditions: Low Anterior Resection Syndrome|Rectal Cancer|Insomnia|Sleep Disorder
Interventions: PROCEDURE: Transanal Irrigation (TAI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Zoledronic Acid Compared to Percutaneous Treatment in Osteoid Osteoma
Status: TERMINATED
Conditions: Osteoid Osteoma
Interventions: DEVICE: Thermal destruction with radiofrequency or laser|DRUG: Acide Zoledronique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Validation of an Intermittent Shuttle Walking Protocol in Patients With COPD
Status: UNKNOWN
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: OTHER: Incremental shuttle walking protocol (ISWT)|OTHER: Endurance shuttle walking (ESW) protocol|OTHER: First Intermittent shuttle walking protocol|OTHER: Second Intermittent shuttle walking protocol|OTHER: Focus group study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Continuous Versus Bolus Feeding in Neonates With Hypoxic Ischemic Encephalopathy
Status: NOT_YET_RECRUITING
Conditions: Hypoxic Ischemic Encephalopathy of Newborn|Feeding Patterns
Interventions: DIETARY_SUPPLEMENT: Bolus feeding|DIETARY_SUPPLEMENT: Continuous feeding|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A 6-Week Safety and Efficacy Study of Travatan Compared to Xalcom in Subjects With Open-Angle Glaucoma(OAG) or Ocular Hypertension(OHT)
Status: COMPLETED
Conditions: Glaucoma, Open-Angle|Ocular Hypertension
Interventions: DRUG: Travoprost (0.004%)|DRUG: Latanoprost (0.005%)/Timolol (0.5%)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Multiple Gingival Recessions
Status: COMPLETED
Conditions: Gingival Recession
Interventions: PROCEDURE: Coronally advanced flap (CAF)|DRUG: Collagen Matrix|PROCEDURE: Subepithelial connective tissue graft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase lb/ll, Open Label, Single Arm Study With Olinvacimab and Capecitabine in mCRC Patients (OLCAP)
Status: WITHDRAWN
Conditions: Colorectal Cancer Metastatic
Interventions: DRUG: Olinvacimab added to Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study in Healthy Men to Test How Well Different Doses of BI 1839100 Are Tolerated (1490-0003)
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BI 1839100|DRUG: Placebo matching BI 1839100
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy & Safety Study of Oral Aripiprazole in Adolescents With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Aripiprazole|DRUG: Aripiprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Mid-point Transverse Process to Pleura Block for Breast Cancer Surgery: A Randomized Controlled Trial
Status: UNKNOWN
Conditions: Breast Cancer|Acute Pain|Anesthesia
Interventions: PROCEDURE: PVB group|PROCEDURE: MTP block group|PROCEDURE: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: REDEFINE 3: A Research Study to See the Effects of CagriSema in People Living With Diseases in the Heart and Blood Vessels
Status: RECRUITING
Conditions: Cardiovascular Disease
Interventions: DRUG: Cagrilintide|DRUG: Semaglutide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Association Between Cardiac ARRHYTHMIAs and Glycemic Variability in Patient With Type 2 Diabetes Monitored Through FREEstyle Libre and Bluetooth Technology.
Status: NOT_YET_RECRUITING
Conditions: Diabetes|Arrhythmias|Atrial Fibrillation|Heart Failure
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Cisplatin and Irinotecan in Treating Patients With Locally Advanced or Metastatic Esophageal or Gastric Cancer
Status: COMPLETED
Conditions: Esophageal Cancer|Gastric Cancer
Interventions: DRUG: cisplatin|DRUG: irinotecan hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Comparison of Spencer Technique and Gongs Mobilization in Patients With Phase ii Adhesive Capsulitis
Status: UNKNOWN
Conditions: Adhesive Capsulitis
Interventions: OTHER: Spencer technique along with conventional treatment|OTHER: Gongs Mobilization along with conventional treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing the Efficacy of Different Zinc Formulations in the Treatment of Diarrhea
Status: COMPLETED
Conditions: Incidence of Acute Diarrhea|Incidence of Abdominal Pain
Interventions: DRUG: Zinc Sulphate|DRUG: Zinc Sulphate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adjunctive Minocycline in Clozapine Treated Schizophrenia Patients
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Minocycline|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Role of Anti-Inflammatory Agents in Patients With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder|Psychosis Not Otherwise Specified|Schizophreniform Disorder
Interventions: DRUG: Ondansetron|DRUG: Simvastatin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An Intervention to Reduce Inappropriate Prescriptions of Antibiotics for Respiratory Infections in General Practice
Status: COMPLETED
Conditions: Respiratory Tract Infections|Anti-Bacterial Agents
Interventions: BEHAVIORAL: Educational intervention|BEHAVIORAL: Educational intervention program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Safety and Efficacy of Intravenous Natalizumab in Acute Ischemic Stroke
Status: COMPLETED
Conditions: Acute Ischemic Stroke
Interventions: DRUG: natalizumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of ADG106 With Advanced or Metastatic Solid Tumors and/or Non-Hodgkin Lymphoma
Status: COMPLETED
Conditions: Solid Tumor|Non-Hodgkin Lymphoma
Interventions: DRUG: ADG106
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Apatinib Plus Irinotecan as Second-line Treatment in AGC or EGJA
Status: UNKNOWN
Conditions: Metastatic Gastric Adenocarcinoma
Interventions: DRUG: Apatinib|DRUG: Irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Evaluate the Efficacy and Safety of Three Different Doses of BAY1817080 Compared to Placebo in Patients With Chronic Cough
Status: COMPLETED
Conditions: Refractory and/or Unexplained Chronic Cough
Interventions: DRUG: BAY1817080|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Use Of AMH for the Discrimination of Polycystic and Multicystic Ovaries in Nonhyperandrogenic Patients
Status: UNKNOWN
Conditions: Polycystic Ovary Syndrome
Interventions: GENETIC: AMH level difference between patient with PCOS and multicystic ovaries.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: PIE II: Pharmacological Intervention in the Elderly II
Status: COMPLETED
Conditions: Diastolic Heart Failure|Heart Failure, Congestive
Interventions: DRUG: Spironolactone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Different Bowel Preparations in CT Colonography: is Diet Necessary? A Randomized Controlled Trial
Status: COMPLETED
Conditions: Cathartic Colon|Colonic Neoplasms
Interventions: PROCEDURE: Diet|DRUG: Faecal Tagging|DRUG: Bowel cleansing|PROCEDURE: CT colonography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Retigabine Efficacy and Safety Trial for Partial Onset Refractory Seizures in Epilepsy
Status: COMPLETED
Conditions: Seizures
Interventions: DRUG: Retigabine|DRUG: Retigabine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Non-inferiority Study of Rituximab Compared to Ocrelizumab in Relapsing MS
Status: RECRUITING
Conditions: Multiple Sclerosis|Multiple Sclerosis, Relapsing-Remitting|Demyelinating Autoimmune Diseases, CNS|Autoimmune Diseases of the Nervous System|Nervous System Diseases|Demyelinating Diseases
Interventions: DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Robotic Athermal Nerve-Sparing Radical Prostatectomy
Status: WITHDRAWN
Conditions: Stage I Prostate Cancer|Stage IIA Prostate Cancer
Interventions: PROCEDURE: robot-assisted laparoscopic surgery|PROCEDURE: robot-assisted laparoscopic surgery|OTHER: laboratory biomarker analysis|OTHER: quality-of-life assessment|OTHER: questionnaire administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of the Safety and Efficacy of Sodium Pentaborate Pentahydrate in Patients With Advanced Renal Cell Carcinoma
Status: NOT_YET_RECRUITING
Conditions: Renal Cell Carcinoma
Interventions: DRUG: Sodium Pentaborate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Efficacy and Safety of Ertugliflozin in Participants With Type 2 Diabetes Mellitus With Stage 3 Chronic Kidney Disease Who Have Inadequate Glycemic Control on Antihyperglycemic Therapy (MK-8835-001)
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Ertugliflozin 5 mg|DRUG: Placebo 5 mg|DRUG: Ertugliflozin 10 mg|DRUG: Placebo 10 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Paclitaxel + Carboplatin With AVB-S6-500 in Women With Stage III or IV Epithelial Ovarian, Primary Peritoneal, or Fallopian Tube Cancer Receiving Neoadjuvant Chemotherapy
Status: WITHDRAWN
Conditions: Epithelial Ovarian Cancer|Primary Peritoneal Carcinoma|Fallopian Tube Cancer
Interventions: DRUG: AVB-S6-500|DRUG: Paclitaxel|DRUG: Carboplatin|PROCEDURE: Tissue from Diagnostic Laparoscopy|PROCEDURE: Tissue from Core biopsy|PROCEDURE: Interval Debulking|PROCEDURE: Peripheral blood|PROCEDURE: Ascites collection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fludeoxyglucose (FDG) F 18 PET Scan, CT Scan, and Ferumoxtran-10 MRI Scan Before Chemotherapy and Radiation Therapy in Finding Lymph Node Metastasis in Patients With Locally Advanced Cervical Cancer or High-Risk Endometrial Cancer
Status: COMPLETED
Conditions: Cervical Adenocarcinoma|Cervical Adenosquamous Cell Carcinoma|Cervical Small Cell Carcinoma|Cervical Squamous Cell Carcinoma|Endometrial Clear Cell Carcinoma|Endometrial Papillary Serous Carcinoma|Stage I Endometrial Carcinoma|Stage IB Cervical Cancer|Stage II Endometrial Carcinoma|Stage IIA Cervical Cancer|Stage IIB Cervical Cancer|Stage III Cervical Cancer|Stage III Endometrial Carcinoma|Stage IVA Cervical Cancer
Interventions: RADIATION: fludeoxyglucose F 18|PROCEDURE: positron emission tomography|PROCEDURE: computed tomography|DRUG: ferumoxtran-10|PROCEDURE: magnetic resonance imaging|PROCEDURE: diagnostic lymphadenectomy|PROCEDURE: lymph node biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation of the Efficacy of National Cancer Institute's Facing Forward Booklet in the Cancer Community Setting
Status: COMPLETED
Conditions: Prostate Cancer|Breast Cancer|Colorectal Cancer|Thoracic Cancer
Interventions: OTHER: CIS (Cancer Information Service) Information Sheet|OTHER: Facing Forward booklet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of Two Doses of Norepinephrine in Preventing Hypotension After Spinal Anesthesia
Status: COMPLETED
Conditions: Anesthesia|Adverse Effect|Hypotension|Cesarean Section Complications|Vasopressor
Interventions: DRUG: Norepinephrine: 1mcg/kg|DRUG: Norepinephrine 0,5mcg/kg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Community-engaged Optimization of COVID-19 Rapid Evaluation And TEsting Experiences
Status: RECRUITING
Conditions: COVID-19|COVID-19 Pandemic
Interventions: BEHAVIORAL: COVID-19 walk-up, on-site testing strategy|BEHAVIORAL: Community Health Worker (CHW) leading testing navigation and general preventive care reminders|BEHAVIORAL: No-cost self-testing kit vending machines
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Combination Chemotherapy With or Without Trastuzumab in Treating Women With Breast Cancer
Status: COMPLETED
Conditions: Breast Neoplasms
Interventions: DRUG: Doxorubicin|DRUG: Cyclophosphamide|DRUG: Docetaxel|DRUG: Herceptin|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Cerebral Hypoperfusion and Its Reversal on Late-Life Depression
Status: TERMINATED
Conditions: Depression|Hypertension
Interventions: DRUG: Sertraline|DRUG: Candesartan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of a Novel Interposition Supraciliary Implant in Patients With Open Angle Glaucoma
Status: TERMINATED
Conditions: Glaucoma, Open-Angle
Interventions: DEVICE: Interposition supraciliary implant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adapting CBT-I for Hazardous Alcohol Users
Status: RECRUITING
Conditions: Insomnia|Harmful; Use, Alcohol
Interventions: BEHAVIORAL: Insomnia Treatment|BEHAVIORAL: Education Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of the Combination of Bortezomib and Clofarabine in Adults With Relapsed Solid Tumors
Status: RECRUITING
Conditions: Neoplasms|Myelodysplastic Syndromes|Lymphomas
Interventions: DRUG: Bortezomib plus Clofarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Transcutaneous Vagus Nerve Stimulation on Upper Limb Function in Stroke Patients
Status: COMPLETED
Conditions: Stroke, Ischemic
Interventions: OTHER: Transcutaneous auricular vagus nerve stimulation|OTHER: selected physical therapy program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Collecting and Storing Tissue From Young Patients With Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Lymphoblastic Leukemia|Acute Myeloid Leukemia|Central Nervous System Neoplasm|Ewing Sarcoma|Germ Cell Tumor|Leukemia|Lymphoma|Malignant Neoplasm|Neuroblastoma|Osteosarcoma|Retinoblastoma|Rhabdoid Tumor|Rhabdomyosarcoma|Soft Tissue Sarcoma
Interventions: OTHER: Cytology Specimen Collection Procedure|OTHER: Laboratory Biomarker Analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Design and Clinical Evaluation of a School Meal With Deworming Properties
Status: COMPLETED
Conditions: Helminthiasis|Tinea Capitis|Anemia
Interventions: DIETARY_SUPPLEMENT: Ujiplus|DRUG: Albendazole|DIETARY_SUPPLEMENT: uji
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Efficacy and Safety of Idebenone vs. Placebo in Prodromal Parkinson Disease
Status: UNKNOWN
Conditions: REM Sleep Behavior Disorder|Parkinson Disease
Interventions: DRUG: Idebenone|DRUG: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acute Psychological Sleep Stabilisation for Patients Hospitalised With Depression
Status: ENROLLING_BY_INVITATION
Conditions: Insomnia|Depression
Interventions: BEHAVIORAL: Acute psychological sleep stabilization|BEHAVIORAL: Sleep hygiene education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ramucirumab and Atezolizumab After Progression on Any Immune Checkpoint Blocker in NSCLC
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer|Non Small Cell Lung Cancer|NSCLC
Interventions: DRUG: Ramucirumab|DRUG: Atezolizumab|PROCEDURE: Peripheral blood draw|PROCEDURE: Biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Capecitabine, Panitumumab, and Radiation Therapy With or Without Irinotecan Hydrochloride in Treating Patients Undergoing Surgery for Localized Rectal Cancer
Status: UNKNOWN
Conditions: Colorectal Cancer
Interventions: BIOLOGICAL: panitumumab|DRUG: capecitabine|DRUG: irinotecan hydrochloride|PROCEDURE: neoadjuvant therapy|PROCEDURE: therapeutic conventional surgery|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Discomfort During Intravenous Cannulation in an Emergency Department: Impact of Communication
Status: COMPLETED
Conditions: Pain, Acute|Catheterization, Peripheral
Interventions: OTHER: Experimental: Intervention message (first phase)|OTHER: Placebo Comparator: Control message (first phase)|OTHER: Experimental: Intervention message (second phase)|OTHER: Placebo Comparator: Control message (second phase)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Study to Allow Access to Nilotinib for Patients Who Are on Nilotinib Treatment in a Novartis-sponsored Study
Status: COMPLETED
Conditions: Chronic Myelogenous Leukemia (CML)|Metastatic Gastrointestinal Stromal Tumors (GIST)|Acute Lymphoblastic Leukemia (ALL)|Receptor Tyrosine Kinase (KIT) Mutated Melanoma
Interventions: DRUG: Nilotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Three Commercial Oral Rehydration Solutions Consumed After Extra-cellular Dehydration
Status: ACTIVE_NOT_RECRUITING
Conditions: Fluid Balance Outcomes
Interventions: OTHER: Composition of oral rehydration solutions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Safety and Efficacy Study of Amdoxovir in HIV-1 Treatment-experienced Subjects
Status: WITHDRAWN
Conditions: Human Immunodeficiency Virus Infection
Interventions: DRUG: amdoxovir 300 mg bid|DRUG: amdoxovir 500 mg bid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: LMB-2 to Treat Hairy Cell Leukemia
Status: COMPLETED
Conditions: Hairy Cell Leukemia
Interventions: DRUG: Anti-Tac(Fv)-PE38 (LMB-2) Immunotoxin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: VOICE-Early Response to Vedolizumab and Ustekinumab in Participants With Crohn's Disease: A Prospective Observational Study
Status: RECRUITING
Conditions: Crohn's Disease
Interventions: DRUG: Vedolizumab (VDZ)|DRUG: Ustekinumab (UST)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Clinical Proof-of-principle Trial in Adult Subjects With Newly Diagnosed Type 1 Diabetes Mellitus Investigating the Effect of NNC0114-0006 and Liraglutide on Preservation of Beta-cell Function
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 1
Interventions: DRUG: NNC0114-0006|DRUG: liraglutide|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Employing End Tidal Capnography in Continuous Flow Ventricular Assist Device Patients
Status: WITHDRAWN
Conditions: Cardiomyopathy|Cardiovascular Disease|Heart Disease
Interventions: DEVICE: Respiratory Depression Monitoring with End Tidal Carbon Dioxide Nasal Cannula (ETCO2- NC)|OTHER: Standard Non-invasive Respiratory Depression Monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Acupuncture Intervention to Improve Neurological Function and Anti-inflammatory Effect in Acute Ischemic Stroke (ANAIS)
Status: COMPLETED
Conditions: Acute Ischemic Stroke|Acupuncture
Interventions: PROCEDURE: Traditional Acupuncture|PROCEDURE: Minimal Acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase IIB Pilot Study of a Modified Dosage Regimen of AMG0001 in Subjects With Critical Limb Ischemia
Status: COMPLETED
Conditions: Critical Limb Ischemia|Vascular Diseases|Peripheral Arterial Disease
Interventions: BIOLOGICAL: HGF Plasmid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Irinotecan Liposome，Albumin Paclitaxel and Gemcitabine First-line Treatment for Pancreatic Cancer
Status: NOT_YET_RECRUITING
Conditions: Pancreatic Cancer
Interventions: DRUG: Irinotecan liposome（40mg/m2）|DRUG: Nab-paclitaxel|DRUG: Gemcitabine|DRUG: Irinotecan Liposome（60mg/m2）
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Evaluation of the Effect of Mesenchymal Stem Cells on the Immune System of Patients With ALS
Status: UNKNOWN
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DRUG: Mesenchymal stem cells isolated from Wharton's jelly
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Local Infiltration Analgesia in Total Hip Arthroplasty
Status: COMPLETED
Conditions: Post-operative Pain
Interventions: DRUG: Ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Metformin in Non Small Cell Lung Cancer (NSCLC)
Status: TERMINATED
Conditions: Lung Cancer
Interventions: DRUG: Metformin|OTHER: Placebo|RADIATION: Stereotactic body Radiotherapy (SBRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective Longitudinal Observational Study to Evaluate the Clinical Characteristics and Opioids Treatments in Patients With Breakthrough Cancer Pain
Status: COMPLETED
Conditions: Tumor|Cancer Pain|Breakthrough Cancer Pain|Neuropathic Pain
Interventions: DRUG: Morphine|DRUG: Fentanyl|DRUG: Methadone|DRUG: Buprenorphine|DRUG: Oxycodone|DRUG: Hydromorphone|DRUG: Tapentadol
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluating the Use of SR34006 Compared to Warfarin or Acenocoumarol in Patients With Atrial Fibrillation (AMADEUS)
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DRUG: SR34006 (idraparinux sodium) Injection|DRUG: vitamin K antagonist (warfarin or acenocoumarol) tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Modified Versus Traditional Thoracic Drainage After Thoracoscopic Surgery
Status: UNKNOWN
Conditions: Lung Neoplasms|Lung Cancer|Pulmonary Neoplasm|Postoperative Pain|Thoracoscopic Surgery
Interventions: PROCEDURE: pigtail catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Retrospective Study to Describe Real-World Treatment Patterns and Clinical Outcomes Among Patients With Myelodysplastic Syndromes
Status: NOT_YET_RECRUITING
Conditions: Myelodysplastic Syndromes (MDS)
Interventions: DRUG: Luspatercept|DRUG: Epoetin Alfa
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Quality of Recovery Following Opioids Free Anaesthesia in Laparoscopic Sleeve Gastrectomy
Status: COMPLETED
Conditions: Narcotics|Recovery Quality|Analgesia|Bariatric Surgery
Interventions: DRUG: Fentanyl|DRUG: Ketamine|DRUG: Dexmedetomidine Injection [Precedex]|PROCEDURE: Oblique subcostal transversus abdominis plane block|DRUG: Lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Istradefylline (KW-6002) for the Treatment of Parkinson's Disease in Patients Taking Levodopa
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DRUG: Istradefylline (KW-6002)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Cost Comparison Study of Darbepoetin Versus Epoetin Therapy to Treat Anemia in Hemodialysis Patients
Status: COMPLETED
Conditions: Anemia|Chronic Kidney Disease
Interventions: DRUG: Epoetin Alfa|DRUG: Darbepoetin alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neurological Outcomes Following Carpal Tunnel Wound-closure Techniques
Status: COMPLETED
Conditions: Carpal Tunnel Syndrome Bilateral
Interventions: PROCEDURE: two-component skin adhesive Glubran Tiss 2®|PROCEDURE: skin stitched with transcutaneous nylon suture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Study of Hemodynamic Changes Caused by Diazepam and Midazolam During Third Molar Surgery
Status: COMPLETED
Conditions: Anxiety
Interventions: DRUG: 7.5 mg Midazolam|DRUG: 10 mg diazepam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Cefepime-AAI101 in the Treatment of Complicated Urinary Tract Infections
Status: COMPLETED
Conditions: Urinary Tract Infections
Interventions: DRUG: cefepime/AAI101 combination|DRUG: Piperacillin/tazobactam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of WF10 (TCDO) on HbA1c Values in Diabetic Foot Ulcer Patients
Status: COMPLETED
Conditions: Diabetic Foot Ulcer (DFU)|Uncontrolled Diabetes With Foot Ulcer
Interventions: DRUG: WF10
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Achieving Better Control for Older Adults With Asthma
Status: COMPLETED
Conditions: Asthma|Elderly
Interventions: BEHAVIORAL: Self-regulation intervention|BEHAVIORAL: Telephone follow-up
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Puerarin Injection on Carotid Intima-Media Thickness in Patients With Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Puerarin injection 400 mg|DRUG: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Talimogene Laherparepvec in Combination With Neoadjuvant Chemotherapy in Triple Negative Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer|Ductal Carcinoma|Invasive Breast Carcinoma|Invasive Ductal Breast Carcinoma
Interventions: BIOLOGICAL: Talimogene laherparepvec|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bevacizumab, Irinotecan and Temozolomide for Relapsed or Refractory Neuroblastoma
Status: COMPLETED
Conditions: Neuroblastoma
Interventions: DRUG: Bevacizumab, Irinotecan and Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Synapse Medicine Decision Support on Inpatient Pharmacist Efficacy and Efficiency
Status: NOT_YET_RECRUITING
Conditions: Infections|Heart Diseases|Lung Diseases|Kidney Diseases|Liver Diseases|Gastrointestinal Diseases
Interventions: OTHER: Synapse medicine platform
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Prophylactic HQP1351 Therapy Post-transplants on Leukemia After Allo-HSCT
Status: WITHDRAWN
Conditions: Prophylactic HQP1351 Therapy|Third Generation TKI
Interventions: DRUG: HQP1351( Olverembatinib dimesylate)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: UCD19 CAR T Therapy in Adults With B-ALL and MRD Positivity in CR1
Status: RECRUITING
Conditions: Acute Lymphoid Leukemia|Acute Lymphoblastic Leukemia
Interventions: DRUG: CD19 Directed CAR T Cell
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT