pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Heme Arginate in Functional Magnetic Resonance Imaging (fMRI)
Status: UNKNOWN
Conditions: Ischemia-reperfusion Injury
Interventions: DRUG: heme arginate administration|DRUG: Placebo administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mindfulness-Based ADHD Treatment for Children: a Feasibility Study
Status: RECRUITING
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: BEHAVIORAL: Mindfulness-Based ADHD Treatment for Children|BIOLOGICAL: Goal-Standard Medication (Treatment as Usual)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acute Intense Paraphilic Desire (DSM-V) Down-Regulation Via taVNS Neuro-Modulation [Transcutaneous Afferent Vagus Nerve] With Future Operative Implant Consideration
Status: NOT_YET_RECRUITING
Conditions: Desire; Sexual, Aversion|Paraphilia
Interventions: DEVICE: transcutaneous (superficial) afferent electrical nerve stimulation specific for vagus nerve
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Exploring Mechanisms for Neuropsychiatric Symptoms of Parkinson Disease Using Transcranial Direct Current Stimulation
Status: RECRUITING
Conditions: Idiopathic Parkinson's Disease|Parkinson Disease|Depression
Interventions: DEVICE: Transcranial Direct Current Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Promoting Male Involvement to Improve Prevention of Mother to Child Transmission (PMTCT) Uptake and Reduce Antenatal Infection
Status: COMPLETED
Conditions: HIV|Pregnancy
Interventions: BEHAVIORAL: PartnerPlus Intervention|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Randomized, Double-Blind, Placebo-Controlled Study of Idelalisib in Combination With Rituximab for Previously Treated Chronic Lymphocytic Leukemia (CLL)
Status: COMPLETED
Conditions: Chronic Lymphocytic Leukemia
Interventions: DRUG: Idelalisib|DRUG: Rituximab|DRUG: Placebo to match idelalisib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Electrical Stimulation Effect on Ankle Instability During Walking in Virtual Reality Setup
Status: RECRUITING
Conditions: Ankle Sprains|Ankle Instability
Interventions: DEVICE: Stochastic Resonance (SR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety and Performance of the Trialign Percutaneous Tricuspid Valve Annuloplasty System (PTVAS)
Status: UNKNOWN
Conditions: Chronic Symptomatic Functional Tricuspid Regurgitation|Tricuspid Valve Insufficiency|Heart Valve Disease
Interventions: DEVICE: Mitralign Percutaneous Tricuspid Valve Annuloplasty System (PTVAS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oblimersen and Gemcitabine in Treating Patients With Advanced Solid Tumor or Lymphoma
Status: TERMINATED
Conditions: Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue|Nodal Marginal Zone B-cell Lymphoma|Recurrent Adult Burkitt Lymphoma|Recurrent Adult Diffuse Large Cell Lymphoma|Recurrent Adult Diffuse Mixed Cell Lymphoma|Recurrent Adult Diffuse Small Cleaved Cell Lymphoma|Recurrent Adult Hodgkin Lymphoma|Recurrent Adult Immunoblastic Large Cell Lymphoma|Recurrent Adult Lymphoblastic Lymphoma|Recurrent Adult T-cell Leukemia/Lymphoma|Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma|Recurrent Grade 1 Follicular Lymphoma|Recurrent Grade 2 Follicular Lymphoma|Recurrent Grade 3 Follicular Lymphoma|Recurrent Mantle Cell Lymphoma|Recurrent Marginal Zone Lymphoma|Recurrent Small Lymphocytic Lymphoma|Splenic Marginal Zone Lymphoma|Stage IV Adult Burkitt Lymphoma|Stage IV Adult Diffuse Large Cell Lymphoma|Stage IV Adult Diffuse Mixed Cell Lymphoma|Stage IV Adult Diffuse Small Cleaved Cell Lymphoma|Stage IV Adult Hodgkin Lymphoma|Stage IV Adult Immunoblastic Large Cell Lymphoma|Stage IV Adult Lymphoblastic Lymphoma|Stage IV Adult T-cell Leukemia/Lymphoma|Stage IV Cutaneous T-cell Non-Hodgkin Lymphoma|Stage IV Grade 1 Follicular Lymphoma|Stage IV Grade 2 Follicular Lymphoma|Stage IV Grade 3 Follicular Lymphoma|Stage IV Mantle Cell Lymphoma|Stage IV Marginal Zone Lymphoma|Stage IV Small Lymphocytic Lymphoma|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: BIOLOGICAL: oblimersen sodium|DRUG: gemcitabine hydrochloride|OTHER: pharmacological study|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Online Hemodiafiltrationlysis in Cytokine Removal
Status: COMPLETED
Conditions: Sepsis|Acute Kidney Injury
Interventions: PROCEDURE: On-line hemodiafiltration|PROCEDURE: High-flux Hemodialysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 1/2 Study of Donafenib in Combination With KN046 in Advanced Gastrointestinal Tumors
Status: RECRUITING
Conditions: Advanced Gastrointestinal Tumors
Interventions: DRUG: Donafenib Tosilate Tablets|BIOLOGICAL: KN046 Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: First-in-Human Safety, Tolerability and Antitumour Activity Study of MTL-CEBPA in Patients With Advanced Liver Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Hepatocellular Carcinoma|Liver Cancer
Interventions: DRUG: MTL-CEBPA|DRUG: Sorafenib 200mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of GSK376501 on CYP450 Activity in Healthy Adult Subjects
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: GSK376501|DRUG: Midazolam|DRUG: Rosiglitazone|DRUG: Flurbiprofen
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transcranial Direct Current Stimulation (tDCS) Augments the Effects of Gamified, Mobile Attention Bias Modification
Status: COMPLETED
Conditions: Anxiety|Stress
Interventions: BEHAVIORAL: ABMT|OTHER: Transcranial direct current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Intravenous (IV) Zanamivir Pharmacokinetics (PK) Study in Hospitalized Neonates and Infants With Influenza Infection
Status: RECRUITING
Conditions: Influenza, Human|Arthralgia
Interventions: DRUG: Zanamivir
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Treatment Regimens (Sitagliptin Versus Liraglutide) on Participants Who Failed to Achieve Good Glucose Control on Metformin Alone (MK-0431-403)
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: sitagliptin|DRUG: liraglutide|DRUG: glimepiride|DRUG: metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Efficacy and Safety of Three Different Doses of SCV 07 in Attenuating Oral Mucositis in Subjects With Head and Neck Cancer
Status: UNKNOWN
Conditions: Oral Mucositis
Interventions: DRUG: SCV-07|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Determine Safety, Pharmakokinetics and Efficacy of the Different Doses of VL-SE-01 in Healthy Participants.
Status: NOT_YET_RECRUITING
Conditions: Healthy Population
Interventions: DIETARY_SUPPLEMENT: CBD Isolate (25 mg/0.5 ml)|DIETARY_SUPPLEMENT: CBD Isolate (40 mg/0.5 ml)|DIETARY_SUPPLEMENT: CBD Isolate (50 mg/0.5 ml)|DIETARY_SUPPLEMENT: CBD Broad Extract (50 mg/0.5 ml)|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Evaluation of Local Doxycycline in Smokers With Chronic Periodontitis
Status: COMPLETED
Conditions: Chronic Periodontitis
Interventions: DRUG: Doxycycline|PROCEDURE: Mechanical debridement|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: TVMR With the Innovalve System Trial - Pilot Study in Italy
Status: RECRUITING
Conditions: Mitral Valve Regurgitation (Degenerative or Functional)
Interventions: DEVICE: Innovalve TMVR system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tissue Removal During Hysterectomy: The Effect of Vaginal Versus Abdominal Morcellation on Surgical Outcomes
Status: WITHDRAWN
Conditions: Fibroids
Interventions: PROCEDURE: abdominal morcellation|PROCEDURE: vaginal morcellation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High-dose Cytarabine/Mitoxantrone Followed by Autotransplantation for t-MDS/t-AML
Status: COMPLETED
Conditions: Myelodysplastic Syndrome|Acute Myeloid Leukemia
Interventions: DRUG: Ara-C|DRUG: Mitoxantrone|DRUG: Etoposide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Choline Nutrition in Children With Cystic Fibrosis
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DIETARY_SUPPLEMENT: Vitamin: Choline Bitartrate (2-hydroxyethyl) trimethylammonium salt 1:1
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Evaluation of Orange Peel Fermentation on Body Fat Lowering Efficacy in Adults
Status: UNKNOWN
Conditions: Fat-lowering
Interventions: DRUG: orange peel fermentation|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Heart Failure Treatment Guided by N-terminal Pro B-type Natriuretic Peptide (NTproBNP) vs Clinical Symptoms and Signs Alone
Status: COMPLETED
Conditions: Heart Failure|Ventricular Dysfunction, Left
Interventions: DRUG: Captopril|DRUG: Enalapril|DRUG: Lisinopril|DRUG: Ramipril|DRUG: Trandolapril|DRUG: Bisoprolol|DRUG: Carvedilol|DRUG: Metoprolol succinate|DRUG: Candesartan|DRUG: Valsartan|DRUG: Eplerenone|DRUG: Spironolactone|DRUG: Diuretics|DRUG: HF treatment according to Swedish guidelines|PROCEDURE: Blood samples|PROCEDURE: The Kansas City Cardiomyopathy Questionnaire (KCCQ)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: RCT Comparing Lightweight vs. Heavyweight Meshes in Incisional Hernia Repair
Status: COMPLETED
Conditions: Incisional Hernia
Interventions: DEVICE: Ultrapro® mesh|DEVICE: Premilene® mesh
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Alpharadin™ (Radium-223 Chloride) Safety and Dosimetry With HRPC That Has Metastasized to the Skeleton
Status: COMPLETED
Conditions: Prostate Cancer|Metastases|Pharmacokinetics
Interventions: DRUG: Radium-223 chloride (BAY88-8223)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Narrowband Ultraviolet B Versus Narrowband Ultraviolet B Plus Ultraviolet A1 for Atopic Eczema
Status: COMPLETED
Conditions: Atopic Eczema
Interventions: RADIATION: combined ultraviolet phototherapy (NB-UVB + UVA1) vs. NB-UVB monotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study To Evaluate The Safety And Therapeutic Equivalence of Tazarotene Foam 0.1% in Subjects With Acne Vulgaris
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: Tazarotene (Fabior™)|DRUG: Tazarotene (Actavis)|DRUG: Vehicle foam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Acute Lymphoblastic Leukemia in Children
Status: COMPLETED
Conditions: Drug/Agent Toxicity by Tissue/Organ|Leukemia
Interventions: DRUG: asparaginase|DRUG: cyclophosphamide|DRUG: cytarabine|DRUG: dexamethasone|DRUG: dexrazoxane hydrochloride|DRUG: doxorubicin hydrochloride|DRUG: etoposide|DRUG: leucovorin calcium|DRUG: mercaptopurine|DRUG: methotrexate|DRUG: methylprednisolone|DRUG: pegaspargase|DRUG: prednisolone|DRUG: therapeutic hydrocortisone|DRUG: vincristine sulfate|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of High Intensity Interval Training and Combined Training in Type 2 Diabetic (T2D) Patients
Status: UNKNOWN
Conditions: Diabetes Mellitus, Type 2|High-Intensity Interval Training|Exercise Training|Hyperglycaemia Due to Type 2 Diabetes Mellitus
Interventions: OTHER: Physical training|OTHER: Light-Emitting Diode (LED) therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Epidural Anesthesia and Analgesia on the Prognosis in Patients Undergoing Pancreatic Cancer Surgery
Status: UNKNOWN
Conditions: Cancer of Pancreas
Interventions: DRUG: GEA|DRUG: PCEA|DRUG: GA|DRUG: PCIA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Social VR Based Intervention on Enhancing Social Interaction Skills in Children With AD/HD
Status: NOT_YET_RECRUITING
Conditions: Attention-Deficit/Hyperactivity Disorder
Interventions: BEHAVIORAL: Social virtual reality|BEHAVIORAL: Traditional social skills
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Somatostatin In Patients With Autosomal Dominant Polycystic Kidney Disease And Moderate To Severe Renal Insufficiency
Status: COMPLETED
Conditions: Autosomal Dominant Polycystic Kidney Disease
Interventions: DRUG: Octreotide-LAR|OTHER: Saline solution.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Neoadjuvant Study of Abemaciclib (LY2835219) in Postmenopausal Women With Hormone Receptor Positive, HER2 Negative Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer|Hormone Receptor Positive Tumor|Early-Stage Breast Carcinoma
Interventions: DRUG: Abemaciclib|DRUG: Loperamide|DRUG: Anastrozole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Medium-Term Supplementation With Herbal Extract for Exercise Performance and Antioxidant Status
Status: COMPLETED
Conditions: Exercise Performance
Interventions: DIETARY_SUPPLEMENT: PhytoDyNAmic|DIETARY_SUPPLEMENT: Inulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety and Efficacy Study of Albiglutide Liquid Drug Product in Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Lyophilized albiglutide DCC pen injector|DRUG: Lyophilized albiglutide DCC pen injector matching placebo|DRUG: Albiglutide liquid auto-injector|DRUG: Albiglutide liquid auto-injector matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacoeconomic Assessment in Nabi-4514 and Nabi-4515 Phase 3 Studies
Status: COMPLETED
Conditions: Smoking Cessation
Interventions: BIOLOGICAL: NicVAX vaccine|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: The Effects of Dry Needling & Kinesio Tape on Anterior Knee Pain
Status: COMPLETED
Conditions: Patellofemoral Pain Syndrome
Interventions: DEVICE: Dry Needling|DEVICE: Kinesio Tape
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: First Time in Human Study of GSK1223249 in Amyotrophic Lateral Sclerosis
Status: COMPLETED
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DRUG: PLACEBO|DRUG: GSK1223249
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Human Challenge Model Refinement With Enterotoxigenic Escherichia Coli Strain B7A
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: BIOLOGICAL: ETEC strain B7A (O148:H28 CS6+ LT+ST+) (Lot 0481) in Buffer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy Study of Gemcitabine, Paclitaxel, and Irradiation in the Treatment of Pancreatic Cancer
Status: WITHDRAWN
Conditions: Carcinoma, Pancreatic Ductal
Interventions: DRUG: Paclitaxel and gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neurofeedback to Treat Depression
Status: RECRUITING
Conditions: MDD
Interventions: BEHAVIORAL: Active Closed Loop Real Time fMRI Neurofeedback|BEHAVIORAL: Sham Closed Loop Real Time fMRI Neurofeedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of a Polyphenol-rich Food Supplement on Cognitive Function in Healthy Aging Adults
Status: COMPLETED
Conditions: Healthy Elderly
Interventions: DIETARY_SUPPLEMENT: Polyphenol-rich extract|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Trial Assessing Light Intensity Exercise on the Health of Older Breast Cancer Survivors
Status: RECRUITING
Conditions: Inflammation|Cognitive Impairment|Anxiety|Alcohol Drinking
Interventions: BEHAVIORAL: Physical Activity|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: CGX1321 in Subjects With Advanced Solid Tumors and CGX1321 With Pembrolizumab or Encorafenib + Cetuximab in Subjects With Advanced GI Tumors (Keynote 596)
Status: UNKNOWN
Conditions: Solid Tumors|GI Cancer
Interventions: DRUG: CGX1321|DRUG: Pembrolizumab|DRUG: encorafenib|DRUG: cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Smartphone-based Remote Symptom Monitoring to Improve Postoperative Rehabilitation Exercise Adherence After Video-assisted Thoracic Surgery (VATS) for Lung Cancer
Status: RECRUITING
Conditions: Lung Neoplasms, Non-Small Cell Lung Cancer|Postoperative Complications|Patient Reported Outcome Measures|Telerehabilitation|Exercise Therapy
Interventions: DEVICE: ePRO based Remote Symptom Management provide by a mobile phone app
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Carboplatin and Gemcitabine in Treating Patients With Advanced Solid Tumors
Status: COMPLETED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: carboplatin|DRUG: gemcitabine hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Primary Care Treatment Integrating Motivation and Exposure
Status: COMPLETED
Conditions: Stress Disorders, Post-Traumatic|Alcohol-Related Disorders
Interventions: BEHAVIORAL: PC-TIME|BEHAVIORAL: PC-TAU
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pulsed Dye Laser Treatment of Acne Vulgaris
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: Fixed combination of clindamycin 1% + benzoyl peroxide 5%|DEVICE: Pulsed dye laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Interactive Medication Reconciliation By Secure Messaging
Status: UNKNOWN
Conditions: Rate of Post-discharge Medication Adherence
Interventions: OTHER: Participants will receive a internet based secure message confirming adherence to post-discharge medication regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Assessing and Addressing Behaviors in Children With Hearing Loss
Status: COMPLETED
Conditions: Hearing Loss|Attention Deficit and Disruptive Behavior Disorders|Parenting
Interventions: BEHAVIORAL: Family Check Up Behavioral Parenting Training Program (BPT)|BEHAVIORAL: Behavioral Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Prevention of Vasovagal Reactions in First-time Blood Donors Using a Combined PSYchological and Physiological Approach
Status: NOT_YET_RECRUITING
Conditions: Vasovagal Reaction
Interventions: OTHER: Psychological strategy|OTHER: Physiological strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: O. Formigenes Colonization in Calcium Oxalate Kidney Stone Disease
Status: RECRUITING
Conditions: Kidney Stone|Kidney Calculi|Urolithiasis|Urolithiasis, Calcium Oxalate|Nephrolithiasis|Nephrolithiasis, Calcium Oxalate|Oxalate Urolithiasis|Oxaluria
Interventions: DIETARY_SUPPLEMENT: Low oxalate fixed diets pre-colonization|DIETARY_SUPPLEMENT: Moderately high oxalate fixed diets pre-colonization|DIETARY_SUPPLEMENT: Colonization with Oxalobacter formigenes|DIETARY_SUPPLEMENT: Low oxalate fixed diets post-colonization|DIETARY_SUPPLEMENT: Moderately high oxalate fixed diets post-colonization
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Neoadjuvant DaRT for Locally Advanced Oral Cavity SCC
Status: NOT_YET_RECRUITING
Conditions: Squamous Cell Carcinoma|Head and Neck Squamous Cell Carcinoma
Interventions: DEVICE: Radiation: Diffusing Alpha Radiation Emitters Therapy (DaRT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Double-blinded, Randomised, Three-period Crossover Euglycaemic Clamp Trial Investigating the Pharmacokinetics, Glucodynamics and Safety of BioChaperone Human Insulin, Human Insulin (Huminsulin® Normal) and Insulin Lispro (Humalog®) in Subjects With Type 1 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus Type 1
Interventions: DRUG: BioChaperone human insulin|DRUG: Huminsulin® Normal|DRUG: Humalog®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Amnion-Based Injections in the Shoulder
Status: WITHDRAWN
Conditions: Osteoarthritis of the Shoulder|Adhesive Capsulitis
Interventions: BIOLOGICAL: Amnion Injection|DRUG: Betamethasone injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Laser Treatment for Onychomycosis in Diabetes
Status: UNKNOWN
Conditions: Diabetes Mellitus, Type 2|Onychomycosis
Interventions: DEVICE: Laser Treatment YAG laser|DRUG: Standard Treatment (control group) terbinafine hydrochloride tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Safety and Immunogenicity of the Live Attenuated Zika Vaccine rZIKV/D4Δ30-713 in Flavivirus-naïve Adults
Status: COMPLETED
Conditions: Zika Virus
Interventions: BIOLOGICAL: rZIKV/D4Δ30-713 (Administered at a dose of 10^3 plaque-forming units (PFUs) by subcutaneous injection)|BIOLOGICAL: Placebo|BIOLOGICAL: rZIKV/D4Δ30-713 (Administered at a dose of using 10^4 plaque-forming units (PFUs) by subcutaneous injection).
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy of CD207 Targeted CAR-T Cell Therapy in Patients With R/R Langerhans Cell Histiocytosis
Status: NOT_YET_RECRUITING
Conditions: Langerhans Cell Histiocytosis
Interventions: BIOLOGICAL: CD207 CAR-T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Efficacy and Pharmacokinetics of CF-301 vs. Placebo in Addition to Antibacterial Therapy for Treatment of S. Aureus Bacteremia
Status: COMPLETED
Conditions: Staphylococcus Aureus Bacteremia|Staphylococcus Aureus Endocarditis
Interventions: BIOLOGICAL: CF-301|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Defining Musical Toxicity and Its Effect on Patient Well-being
Status: NOT_YET_RECRUITING
Conditions: Breast Carcinoma|Esophageal Carcinoma|Head and Neck Carcinoma|Lung Carcinoma|Malignant Brain Neoplasm|Malignant Solid Neoplasm
Interventions: OTHER: Non-Interventional Study
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Compare the Efficacy and Safety of Surfolase CR Tablet With Surfolase Capsule in Patients With Acute Bronchitis
Status: COMPLETED
Conditions: Acute Bronchitis
Interventions: DRUG: Acebrophylline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Influence of DHA-rich Supplement on DHA-status and Health Evolution of Patients With Cystic Fibrosis
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: Giving DHA-rich supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Test the Safety of Three Experimental HIV Vaccines
Status: COMPLETED
Conditions: HIV Infections|HIV Seronegativity
Interventions: BIOLOGICAL: HIV p24/MF59 Vaccine|BIOLOGICAL: ALVAC-HIV MN120TMG (vCP205)|BIOLOGICAL: ALVAC-RG Rabies Glycoprotein (vCP65)|BIOLOGICAL: rgp120/HIV-1 SF-2
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Analysis of the Effects on Human Tissues After Application of Therapeutic Modalities.
Status: COMPLETED
Conditions: Humans|Young Adults|Health
Interventions: OTHER: Exclusively ice pack|OTHER: Ice pack added 10% of water|OTHER: Ice pack added 100% of water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Web-Based Multi-Resource Training on the Prevention of Urinary Tract Infections in Adult Kidney Transplant Recipients
Status: COMPLETED
Conditions: Kidney Transplantation|Adult|Urinary Tract Infections|Prevention|Medical Informatics
Interventions: OTHER: Web-Based Multi-Source Training on the Prevention of Urinary Tract İnfections
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: uSINE-PAMS Artificial Intelligence Driven, Ultrasound-Guided Lumbar Puncture to Improve Procedural Accuracy
Status: RECRUITING
Conditions: Ultrasound Therapy|Lumbar Puncture
Interventions: PROCEDURE: Intervention Arm (uSINE-PAMS-technique)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy of a Cryogenic Medical Device on Skin Tags Versus a Comparator Product.
Status: COMPLETED
Conditions: Skin Tags
Interventions: DEVICE: Pixie® skin tag|DEVICE: Wortie® Skin Tag Remover
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparison of How Likely it is That Different Tablets of Oxycodone Will be Broken up and Snorted by Adults Who Sometimes Take Drugs for Pleasure
Status: COMPLETED
Conditions: Substance Abuse
Interventions: DRUG: Oxycodone IR ADF|DRUG: Oxycodone API powder|DRUG: Placebo to match oxycodone API powder|DRUG: Placebo to match manipulated oxycodone IR ADF.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Diagnostic Performance of Smart Supra Perimetry (The DPSSP Study)
Status: COMPLETED
Conditions: Glaucoma, Suspect|Glaucoma
Interventions: DIAGNOSTIC_TEST: Humphrey Visual Field Test|DIAGNOSTIC_TEST: Optical Coherence Tomography (OCT) Scan|DIAGNOSTIC_TEST: Smart Perimetry - Henson 9000
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of LY2875358 in Participants With Advanced Cancer
Status: COMPLETED
Conditions: Advanced Cancer
Interventions: DRUG: LY2875358|DRUG: LY2875358 + erlotinib|DRUG: LY2875358 at Part A highest dose|DRUG: LY2875358 at Part A highest dose + trametinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Virtual Group Fitness and Nutrition Intervention for Individuals With Psychosis
Status: COMPLETED
Conditions: Schizophrenia Spectrum Disorder (SSD)
Interventions: BEHAVIORAL: Group Fitness|OTHER: Nutrition education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study of the Effect of Arterial Carbon Dioxide Tension on the Recovery of Spontaneous Respiration
Status: COMPLETED
Conditions: Surgery|Anesthesia
Interventions: OTHER: Continuation of High Frequency Jet Ventilation (HFJV)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Interacting Together Everyday: Recovery After Childhood Traumatic Brain Injury (TBI) "I-InTERACT
Status: COMPLETED
Conditions: Traumatic Brain Injury
Interventions: BEHAVIORAL: Internet-based Interacting Together Everyday: Recovery After Childhood TBI|BEHAVIORAL: Internet Resources Comparison
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, and Immunogenicity of V114 in Healthy Infants (V114-025)
Status: COMPLETED
Conditions: Pneumococcal Infections
Interventions: DRUG: Rotarix™|DRUG: Infanrix™ hexa|DRUG: V114|DRUG: Prevenar 13™
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: VITamin D and OmegA-3 TriaL: Interrelationship of Vitamin D and Vitamin K on Bone (VITAL)
Status: ACTIVE_NOT_RECRUITING
Conditions: Bone Density|Bone Health|Fractures
Interventions: DIETARY_SUPPLEMENT: Vitamin D3 placebo|DIETARY_SUPPLEMENT: Fish oil placebo|DRUG: Omega-3 fatty acids (fish oil)|DIETARY_SUPPLEMENT: Vitamin D3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Laser Ablation Versus Radiofrequency Ablation for Thyroid Nodules
Status: UNKNOWN
Conditions: Thyroid Nodule
Interventions: DEVICE: Percutaneous Laser Ablation|DEVICE: Percutaneous Radiofrequency Ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: General Anesthesia Versus Spinal Anesthesia in Patients of HELLP Syndrome
Status: COMPLETED
Conditions: HELLP Syndrome
Interventions: PROCEDURE: Spinal Anesthesia|PROCEDURE: General Anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Accuracy and Reliability of Novii: Fetal Heart Rate (FHR), Maternal Heart Rate (MHR) and Uterine Contraction (UA) Compared With Doppler, Scalp Fetal Scalp Electrode (FSE), Tocodynamometer (TOCO) and Intra Uterine Pressure Catheter (IUPC)
Status: COMPLETED
Conditions: Term Labour
Interventions: DEVICE: Monica Novii Wireless Patch System
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Postprandial Gut Hormone Responses in Patients With Type 1 Diabetes Mellitus
Status: UNKNOWN
Conditions: type1diabetes|Hunger|Obesity
Interventions: DIAGNOSTIC_TEST: Standardized test meal
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Caries Arresting in Primary Molar Teeth Using SDF VS ART
Status: UNKNOWN
Conditions: Dental Caries
Interventions: OTHER: SDF|OTHER: SDF + ART (SMART technique )
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Evolocumab in Patients With Diabetes and Atherosclerotic Vascular Disease
Status: COMPLETED
Conditions: Atherosclerotic Vascular Disease|Type2 Diabetes|Microvascular Dysfunction
Interventions: DRUG: Placebo|DRUG: Evolocumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Gene Therapy for WAS
Status: COMPLETED
Conditions: Wiskott-Aldrich Syndrome
Interventions: GENETIC: Autologous CD34 positive cells transduced with a lentiviral vector containing human WAS gene
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low-level Laser Acupuncture Reduces Postoperative Pain and Morphine-related Side Effects in Patients With Total Knee Arthroplasty:
Status: COMPLETED
Conditions: Low-level Laser Acupuncture in Patients With Total Knee Arthroplasty
Interventions: DEVICE: low-level laser|DEVICE: Sham laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: SSI Rates in Patients Undergoing Mastectomy Without Reconstruction- A Multicenter, Double-blinded RCT.
Status: UNKNOWN
Conditions: Surgical Site Infection
Interventions: DRUG: Cephalexin 500 MG|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Tolerability of Apevitin BC Comparing to Vitamin Complex in Stimulating the Appetite
Status: COMPLETED
Conditions: Lack or Loss Appetite Nonorganic Origin
Interventions: DRUG: Apevitin BC|DRUG: Vitamin B Complex + Vitamin C
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study in Healthy Subjects to Investigate Whether Administration of Clazosentan Can Affect Normal Heart Function
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: Clazosentan|DRUG: Placebo|DRUG: Moxifloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: COMPARISON OF CONTINUOUS VERSUS INTERRUPTED-X SUTURING TECHNIQUE FOR CLOSURE OF RECTUS SHEATH IN PATIENTS UNDERGOING EMERGENCY LAPAROTOMY FOR HOLLOW VISCUS PERFORATION
Status: RECRUITING
Conditions: Duodenal Perforation|Bowel Perforated
Interventions: PROCEDURE: Continuous suturing|PROCEDURE: Interrupted X suturing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of High-grade Gliomas Using Hypofractionated Radiation Therapy -a Phase I Clinical Trial
Status: COMPLETED
Conditions: Glioma|Radiotherapy, Intensity-Modulated|Maximum Tolerated Dose
Interventions: RADIATION: hypofractionated radiation|DRUG: Temozolomide chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SNS for Treatment of PD Gait Disorder
Status: UNKNOWN
Conditions: Parkinson Disease|Gait Disorders, Neurologic
Interventions: DEVICE: Sacral Nerve Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of rTMS Analgesic Effect in Chronic Neuropathic Pain,
Status: RECRUITING
Conditions: Chronic Neuropathic Pain
Interventions: DEVICE: RepetitiveTranscranial Magnetic Stimulation (rTMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect ''of Follow-up With the Mobile Application'' on Treatment Compliance in Patients With Hypertension
Status: COMPLETED
Conditions: Hypertension
Interventions: BEHAVIORAL: The Effect of the Mobile Application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: TQB2450 Combined With Anlotinib Hydrochloride in the Perioperative Treatment of Hepatocellular Carcinoma Hydrochloride Neoadjuvant Therapy for Resectable Hepatocellular Carcinoma With a High Risk of Recurrence or Metastasis
Status: UNKNOWN
Conditions: Patients With Resectable Hepatocellular Carcinoma Who Are at High Risk of Recurrence or Metastasi
Interventions: DRUG: Anlotinib hydrochloride capsules＋ TQB2450 injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Polyamine-enriched Diet in Elderly Individuals With Subjective Cognitive Decline
Status: COMPLETED
Conditions: Subjective Cognitive Decline (SCD)
Interventions: DIETARY_SUPPLEMENT: Polyamine|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Hydroxychloroquine and Zinc in the Prevention of COVID-19 Infection in Military Healthcare Workers
Status: UNKNOWN
Conditions: Sars-CoV2|COVID19
Interventions: DRUG: Hydroxychloroquine|DRUG: Hydroxychloroquine (placebo)|DRUG: Zinc|DRUG: Zinc (Placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Radiomics for Prediction of Lymph Node Metastasis in Gastric Cancer（RPLNM）(GIPMCS-1701)
Status: UNKNOWN
Conditions: Digestive System Diseases|Gastrointestinal Neoplasms|Digestive System Neoplasms|Gastrointestinal Diseases|Stomach Neoplasms
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Optional Sub-study to Intraoperative Imaging With ICG Registry
Status: COMPLETED
Conditions: Lung, Prostate, Breast, Colon, Pancreatic, Renal, Bladder,Thyroid, Ovarian, Head and Neck,GI (Foregut - Esophagus),GI (Midgut) Cancer|Cancer of the Ovarian, Head and Neck,GI (Foregut - Esophagus),GI (Midgut), Sarcoma Cancer|Cancer of Neuro-onc, Parathyroid, Desmoid Tumors, Melanoma Cancer
Interventions: OTHER: data collection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Immunogenicity of Two Doses of Monovalent Inactivated Influenza Vaccine That is Adjuvanted With MF59C.1 (MF59) and Uses a Surface Antigen From a Potential Pandemic Virus Strain Candidate (H5N1) in Adult and Elderly Subjects
Status: COMPLETED
Conditions: Prepandemic Influenza Vaccine
Interventions: BIOLOGICAL: Monovalent inactivated influenza vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Laser Ablation Versus Mechanochemical Ablation Trial
Status: COMPLETED
Conditions: Varicose Veins
Interventions: DEVICE: EVLA|DEVICE: ClariVein®|DRUG: Lidocaine with 1:200,000 epinephrine solution|DRUG: Lidocaine with 1:200,000 epinephrine solution|DRUG: Sodium Bicarbonate|DRUG: Sodium Tetradecyl Sulphate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Olanzapine Treatment of Patients With Bipolar I Disorder
Status: COMPLETED
Conditions: Depression, Bipolar
Interventions: DRUG: Olanzapine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Metformin as an Adjunctive Therapy to Catheter Ablation in Atrial Fibrillation
Status: RECRUITING
Conditions: Atrial Fibrillation
Interventions: DRUG: Metformin|BEHAVIORAL: Recommendations for lifestyle modification.|DEVICE: AliveCor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Photodynamic Therapy Using Silicon Phthalocyanine 4 in Treating Patients With Actinic Keratosis, Bowen's Disease, Skin Cancer, or Stage I or Stage II Mycosis Fungoides
Status: COMPLETED
Conditions: Lymphoma|Non-melanomatous Skin Cancer|Precancerous Condition
Interventions: DRUG: silicon phthalocyanine 4
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intravitreal Dexamethasone Implant for Persistent Macular Thickening and Edema After Vitrectomy for Epiretinal Membrane
Status: TERMINATED
Conditions: Macular Edema|Epiretinal Membrane|Vitrectomy
Interventions: DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics, Efficacy, Gametocyte Carriage, Birth Outcomes Following Sulfadoxine-pyrimethamine Intermittent Presumptive Treatment in Pregnant Women
Status: COMPLETED
Conditions: Malaria
Interventions: DRUG: sulfadoxine-pyrimethamine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Treatment of Primary Menstrual Pain With Kanion Capsule
Status: COMPLETED
Conditions: Primary Dysmenorrhea
Interventions: DRUG: Kanion Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Raltegravir in a Diverse Cohort of HIV-Infected Patients (0518-055)
Status: COMPLETED
Conditions: Human Immunodeficiency Virus
Interventions: DRUG: Comparator: raltegravir
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Dexmedetomidine on Oxygen During One Lung Ventilation in Pediatric Surgery.
Status: COMPLETED
Conditions: One Lung Ventilation OLV|Esophageal Atresia|Hydrocystoma|Pneumonectomy|Pleura; Abscess
Interventions: DRUG: Dexmedetomidine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 1, Multiple Dose Study of MPC-6827 in Subjects With Refractory Solid Tumors
Status: COMPLETED
Conditions: Refractory Solid Tumors
Interventions: DRUG: MPC-6827
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pemetrexed Disodium Plus Gemcitabine in Treating Patients With Locally Advanced or Metastatic Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DRUG: gemcitabine hydrochloride|DRUG: pemetrexed disodium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT