pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Pembrolizumab, Lenvatinib and IL-15 Superagonist N-803 in Combination With HER2 Targeting Autologous Dendritic Cell (AdHER2DC) Vaccine in Participants With Advanced or Metastatic Endometrial Cancer
Status: RECRUITING
Conditions: Endometrial Cancer|Cancer of Endometrium|Carcinoma of Endometrium|Endometrial Carcinoma
Interventions: BIOLOGICAL: AdHER2DC vaccine|BIOLOGICAL: Pembrolizumab|BIOLOGICAL: N-803|DRUG: Lenvatinib|DEVICE: PATHWAY HER2 (4B5) assay
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transection Versus Ligation of Internal Spermatic Vessels in Laparoscopic Fowler-Stephens Orchidopexy
Status: NOT_YET_RECRUITING
Conditions: Cryptorchidism
Interventions: PROCEDURE: Transection of internal spermatic vessels in first stage laparoscopic Fowler-Stephens orchidopexy for intra-abdominal testis|PROCEDURE: Ligation of internal spermatic vessels in first stage laparoscopic Fowler-Stephens orchidopexy for intra-abdominal testis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Influence of Type of Anesthesia on Postoperative Pain
Status: ACTIVE_NOT_RECRUITING
Conditions: Colo-rectal Cancer|Anesthesia
Interventions: DRUG: Propofol|DRUG: Sevoflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Bubiket Study: Ultrasound Guided Fascia Iliaca Nerve Block With Bupivacaine and Adjuvant Ketamine vs. Bupivacaine Alone
Status: WITHDRAWN
Conditions: Pain, Musculoskeletal
Interventions: DRUG: Bupivacaine|DRUG: Ketamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Travatan Z in Ocular Surface Health in Patients With Open-Angle Glaucoma or Ocular Hypertension
Status: COMPLETED
Conditions: Open-angle Glaucoma|Ocular Hypertension
Interventions: DRUG: Travoprost ophthalmic solution 0.004% with SofZia® preservative system (TRAVATAN Z®)|DRUG: Latanoprost ophthalmic solution 0.005% (XALATAN®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Food Study of Rabeprazole Sodium Delayed-Release Tablets 20 mg to Aciphex® Tablets 20 mg
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Rabeprazole Sodium Delayed-Release Tablets 20 mg|DRUG: Aciphex® Tablets 20 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Cadonilimab Plus Nab -Paclitaxel for Patients With Recurrent, or Metastatic Cervical Cancer Resistant to Immune Checkpoint Inhibitors
Status: NOT_YET_RECRUITING
Conditions: Uterine Cervical Neoplasms|Cancer of Cervix|Cervical Cancer|Cervical Neoplasms|Uterine Cervical Cancer|Cancer of the Uterine Cervix
Interventions: DRUG: Cadonilimab|DRUG: Nab paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Magnesium Iron Hydroxycarbonate for the Reduction of High Blood Phosphate in Hemodialysis Patients
Status: COMPLETED
Conditions: Chronic Kidney Failure
Interventions: DRUG: Fermagate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Safety of Nanoparticle Albumin-bound (NAB)-Paclitaxel Plus Cisolation Versus CEP (Cisplatin, Epirubicin,Cyclophosphamide) in Induction Therapy for Thymoma: a Study for a Single-center Prospective Phase II Randomized Controlled Train.
Status: NOT_YET_RECRUITING
Conditions: Histological or Cytological Confirmed Stage Ⅲ and Ⅳa Thymoma
Interventions: DRUG: NAB-Paclitaxel plus Cisplatin|DRUG: Cisplatin plus Epirubicin plus Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Assessment of the Effectiveness of TA Versus LEEP for Cervical Cancer Risk Reduction in WLHIV in Mozambique
Status: RECRUITING
Conditions: HIV Infections|HPV Infection|CIN 2/3
Interventions: DEVICE: Thermal ablation|PROCEDURE: LOOP ELECTROSURGICAL EXCISION PROCEDURE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Effects of Modified Cervical Retraction and Motor Control Therapeutics Exercises in Cervical Spondylosis
Status: COMPLETED
Conditions: Cervical Spondylosis
Interventions: OTHER: Modified Cervical Retraction Exercises (MCRE)|OTHER: Motor Control therapeutic exercise(MCTE)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Systemic Pharmacokinetic Study of T4032 (Unpreserved Bimatoprost 0.01%) Eye Gel Versus Lumigan® 0.01% Eye Drops in 40 Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Bimatoprost Ophthalmic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Methorexate and Knee Osteoarthritis
Status: COMPLETED
Conditions: Pain Reduction|Physical Function Improvement
Interventions: DRUG: 25 mg/week oral methotrexate tablets|DRUG: 25mg/week oral placebo tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of a Unified Transdiagnostic Treatment in Routine Care
Status: COMPLETED
Conditions: Anxiety|Traumatic Stress Disorders|Depression
Interventions: OTHER: Unified protocol|OTHER: Routine Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Hepatitis C Virus Donor Positive Kidney Transplantation for Hepatitis C Virus Negative Recipients
Status: COMPLETED
Conditions: Kidney Transplant|Hepatitis C
Interventions: DRUG: Direct acting Anti-Viral Therapy using Epclusa or Zepatier
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RCT of Vapendavir in Patients With COPD and Human Rhinovirus/Enterovirus Upper Respiratory Infection
Status: RECRUITING
Conditions: COPD Exacerbation Acute|COPD With Acute Lower Respiratory Infection|Rhinovirus|Virus Diseases|Virus Infection, RNA|Enterovirus|Enterovirus Infections|Rhinovirus Infection|Infection Viral|Respiratory Complication|Respiratory Disease|Respiratory Tract Infections|Respiratory Tract Diseases|Respiratory Viral Infection|Upper Resp Tract Infection|Upper Respiratory Tract Infections|Upper Respiratory Disease|Upper Respiratory Disorder|Upper Respiratory Disease, Acute|Upper Respiratory Infection Viral|Infections, Respiratory|Infections|Copd|Viral Infection|Emphysema or COPD|Lower Respiratory Disease|Lower Respiratory Disorder|Lower Respiratory Tract and Lung Infections|Pulmonary Disease|Pulmonary Disease, Chronic Obstructive|Respiratory Disease Chronic|Lung Diseases|Lung Disease Chronic|Obstructive Pulmonary Disease|Chronic Lower Respiratory Diseases|Chronic Respiratory Disease
Interventions: DRUG: Vapendavir|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Age-gender on the Pharmacokinetic and Pharmacodynamic Profiles of BIA 5 1058
Status: TERMINATED
Conditions: Pulmonary Arterial Hypertension
Interventions: DRUG: BIA 5-1058
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy With Pembrolizumab Continuation After Progression to PD-1/L1 Inhibitors
Status: UNKNOWN
Conditions: Non-small Cell Lung Cancer Metastatic
Interventions: DRUG: Pembrolizumab plus chemotherapy|DRUG: Placebo plus chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Respiratory Exercises On The Intravaginal Ejaculation Latency Time
Status: COMPLETED
Conditions: Premature Ejaculation
Interventions: OTHER: Pelvic floor exercises and behavioral therapy|OTHER: Respiratory exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Staph Intervention for Effective Local Defense
Status: RECRUITING
Conditions: Staphylococcus Aureus Infection
Interventions: COMBINATION_PRODUCT: Mupirocin + Nozin + chlorhexidine gluconate|BEHAVIORAL: Education + Household supplies
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Reducing Involuntary Movements in Participants With Tardive Dyskinesia
Status: COMPLETED
Conditions: Tardive Dyskinesia
Interventions: DRUG: SD-809|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Caffeine on Anxiety, Emotional Processing, Approach-avoidance Behavior, and Interoception in Panic Disorder
Status: COMPLETED
Conditions: Panic Disorder|Healthy
Interventions: DIETARY_SUPPLEMENT: Caffeine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Dapagliflozin in Non-diabetic Patients With Proteinuria
Status: COMPLETED
Conditions: Chronic Kidney Diseases|Proteinuria
Interventions: DRUG: Dapagliflozin 10mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Product Performance of a Low Add MultiFocal Soft Contact Lens
Status: COMPLETED
Conditions: Presbyopia
Interventions: DEVICE: LD118033 contact lens|DEVICE: PureVision multifocal contact lens
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SCREENING
Clinical trial: A Study of Rofecoxib in Familial Adenomatous Polyposis (FAP) (0966-205)(TERMINATED)
Status: TERMINATED
Conditions: Adenomatous Polyposis Coli
Interventions: DRUG: MK0966; rofecoxib / Duration of Treatment: 24 weeks|DRUG: Comparator: placebo / Duration of Treatment: 24 weeks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Innohep® in Elderly Patients With Impaired Renal Function Treated for Acute Deep Vein Thrombosis
Status: COMPLETED
Conditions: Deep Vein Thrombosis
Interventions: DRUG: innohep®|DRUG: Heparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Volasertib Combined With Induction Chemotherapy in Acute Myeloid Leukemia
Status: WITHDRAWN
Conditions: AML
Interventions: DRUG: Volasertib|DRUG: Cytarabine|DRUG: Idarubicin|PROCEDURE: Bone Marrow Biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Interscalene Block With Liposomal Bupivacaine vs. Interscalene Block With Bupivacaine and Adjuvants
Status: TERMINATED
Conditions: Shoulder Arthroplasty
Interventions: DRUG: Liposomal bupivacaine|DRUG: Bupivacaine with adjuvants
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of HBV-TCR T Cells (LioCyx-M) as Monotherapy or as Combination With Lenvatinib for HBV-related HCC
Status: NOT_YET_RECRUITING
Conditions: Hepatocellular Carcinoma|Liver Cancer, Adult|Liver Cell Carcinoma
Interventions: BIOLOGICAL: LioCyx-M|DRUG: Lenvatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial on Intraoperative Neuromonitoring (IONM) in Thyroid Cancer Surgery.
Status: UNKNOWN
Conditions: Malignant Neoplasm of Thyroid Gland
Interventions: DEVICE: IONM tube
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Different Feeding Modes on Psychological Condition and Experience in Stroke Patients
Status: NOT_YET_RECRUITING
Conditions: Ischemic Stroke
Interventions: DEVICE: Nasogastric Tube Feeding|DEVICE: Intermittent Oro-esophageal Tube Feeding|BEHAVIORAL: comprehensive rehabilitation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Irritable Bowel Syndrome (IBS) Functional Magnetic Resonance Imaging (fMRI) With Desipramine
Status: COMPLETED
Conditions: Irritable Bowel Syndrome
Interventions: DRUG: Desipramine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nilotinib for First-line Newly Diagnosed CML-CP Patients
Status: UNKNOWN
Conditions: Chronic Myeloid Leukemia, Chronic Phase|Nilotinib
Interventions: DRUG: Nilotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HSS Covid-19 Antibody Serology Among Surgeons & Anesthesiologists
Status: COMPLETED
Conditions: COVID
Interventions: DIAGNOSTIC_TEST: SARS-CoV2 serum antibody testing
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Chewing Gum to Prevent Nausea and Vomiting After Caesarean Section Under Spinal Anaesthesia
Status: UNKNOWN
Conditions: PONV
Interventions: OTHER: Chewing Gum|DRUG: Ondansetron 4 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Reversing Ticagrelor's Effects With Fresh Platelets
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DRUG: Ticagrelor loading dose|DRUG: Aspirin loading dose|DRUG: Ticagrelor maintenance dose|DRUG: Aspirin maintenance dose
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Enzastaurin in Combination of Capecitabine to Treat Breast Cancer
Status: TERMINATED
Conditions: Breast Cancer
Interventions: DRUG: enzastaurin|DRUG: placebo|DRUG: capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Targeted Treatment for ALK Positive Patients Who Have Previously Been Treated for Non-squamous Non-small Cell Lung Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Lung Non-Squamous Non-Small Cell Carcinoma|Stage IV Lung Cancer AJCC v8|Stage IVA Lung Cancer AJCC v8|Stage IVB Lung Cancer AJCC v8
Interventions: DRUG: Alectinib|DRUG: Brigatinib|DRUG: Carboplatin|DRUG: Ceritinib|DRUG: Cisplatin|DRUG: Crizotinib|DRUG: Ensartinib|DRUG: Lorlatinib|DRUG: Pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparative Study: Non-Surgical Spinal Decompression and Spinal Manipulative Therapy- Utilizing a Quantifiable Musculoskeletal Functional Assessment Risk Analysis Tool (MSDR®) in Patients With Chronic Low Back Pain
Status: UNKNOWN
Conditions: Chronic Low Back Pain
Interventions: OTHER: MSDR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Measure Exposure Of Tanezumab In Healthy Volunteers When Administering The Drug Subcutaneously
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: BIOLOGICAL: tanezumab|BIOLOGICAL: tanezumab|BIOLOGICAL: tanezumab|BIOLOGICAL: tanezumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multiple Ascending-Dose Study to Evaluate the Safety, Tolerability and Pharmacokinetics of BMS-933043 in Healthy Subjects
Status: COMPLETED
Conditions: Healthy Adult Normals
Interventions: DRUG: BMS-933043|DRUG: Placebo matching with BMS-933043|DRUG: Antacid Buffer Predose Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Treatment With Topical Eflornithin After Laser Treatment in Women With Facial Hirsutism
Status: COMPLETED
Conditions: Hirsutism
Interventions: DRUG: Eflornithine cream 11.5 w/w %
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Post-Marketing Study of the Immunogenicity of Somatropin (Ribosomal Deoxyribo Nucleic Acid [rDNA] Origin) Injection (Nutropin AQ®) in Children With Growth Hormone Deficiency
Status: COMPLETED
Conditions: Growth Hormone Deficiency
Interventions: DRUG: Somatropin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess Efficacy and Safety of ASP1941 in Diabetic Patients With Renal Impairment
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: ASP1941|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dextromethorphan for Treatment of Postoperative Pain
Status: RECRUITING
Conditions: Post-operative Pain
Interventions: DRUG: Dextromethorphan Hydrobromide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare Two Dose Strengths of CVT-301 (Levodopa Inhalation Powder) With an Oral Dose of Sinemet® (Carbidopa-levodopa) Tablets
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: DRUG: CVT-301 (Dose Level 1)|DRUG: CVT-301 (Dose Level 2)|DRUG: Sinemet®
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Investigation of the Antidepressant Efficacy of the 5-HT2A Antagonist, M100907, in Combination With Citalopram in Treatment Resistant Depression
Status: COMPLETED
Conditions: Depressive Disorder
Interventions: DRUG: MDL100.907
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Unrefined Salmon Oil as Dietary Supplement in Patient With Chronic Obstructive Pulmonary Disease
Status: NOT_YET_RECRUITING
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DIETARY_SUPPLEMENT: CARDIO®|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effects Of Supervised Sensorimotor Training Through Telerehabilitation Monitoring After Total Knee Arthroplasty
Status: RECRUITING
Conditions: Arthropathy of Knee
Interventions: OTHER: experimental treatment|OTHER: common treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of 8 oz Fresh vs. Commercial Orange Juice on Blood Pressure In Normotensive Males Aged 18-59
Status: COMPLETED
Conditions: Blood Pressure
Interventions: DIETARY_SUPPLEMENT: fresh orange juice|DIETARY_SUPPLEMENT: concentrated orange juice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Comparison of the Efficacy of Dextrose Prolotherapy and Mesotherapy in Lateral Epicondylitis
Status: RECRUITING
Conditions: Lateral Epicondylitis
Interventions: PROCEDURE: Mesotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of 2 Different Flow Rates During Oocyte Retrieval
Status: COMPLETED
Conditions: Infertility
Interventions: PROCEDURE: Oocyte retrieval with low aspiration flow rate|PROCEDURE: Oocyte retrieval with high aspiration flow rate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of a Maintenance Therapy With Immunomodulator MGN1703 in Patients With Advanced Colorectal Carcinoma
Status: COMPLETED
Conditions: Advanced Colorectal Carcinoma
Interventions: DRUG: MGN1703|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Long-term Safety Study of BHV-3500 (Zavegepant*) for the Acute Treatment of Migraine
Status: COMPLETED
Conditions: Acute Migraine
Interventions: DRUG: Zavegepant (BHV-3500)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Recovery of Bupivacaine or Bupivacaine-Lidocaine Spinal Anesthesia and Infiltration Anesthesia in Herniorrhaphy
Status: COMPLETED
Conditions: Anesthesia|Inguinal Hernia
Interventions: PROCEDURE: spinal anesthesia|PROCEDURE: spinal anesthesia|PROCEDURE: infiltration anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Pulsed Radiofrequency Treatment in Lumbar Facet-Related Pain
Status: COMPLETED
Conditions: Facet Joint Pain|Pain Syndrome|Pain, Chronic
Interventions: PROCEDURE: Intra-articular pulsed radiofrequency|PROCEDURE: Median branch pulsed radiofrequency
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 360 Degree Expanded Diaphragm Breathing Pattern Training in Individuals With Urinary Incontinence
Status: COMPLETED
Conditions: Urinary Incontinence
Interventions: OTHER: kegel exercises|OTHER: 360 degree expanded diaphragmatic breathing training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Bonviva/Boniva (Ibandronate) in Biphosphonate-Naïve Women With Post-Menopausal Osteoporosis
Status: COMPLETED
Conditions: Post Menopausal Osteoporosis
Interventions: DRUG: ibandronate [Bonviva/Boniva]
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of Three Influenza Vaccines Adults Ages 18 and Older
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: QIVc|BIOLOGICAL: TIV1c|BIOLOGICAL: TIV2c
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Phase 1 Dose Escalation Study of Oral VX-708 in Healthy Participants
Status: COMPLETED
Conditions: Acute Pain
Interventions: DRUG: VX-708|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: TMS for Smoking Cessation in PLWHA Cessation in People Living With HIV/AIDS (PLWHA)
Status: COMPLETED
Conditions: Smoking Cessation|HIV|Craving
Interventions: DEVICE: iTBS|DEVICE: TMS
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multiple Ascending Dose Study of Intravenously Administered BMS-986168 (BIIB092) in Patients With Progressive Supranuclear Palsy
Status: COMPLETED
Conditions: Progressive Supranuclear Palsy
Interventions: DRUG: BIIB092|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Remifentanil Target-controlled Infusion and Dexmedetomidine Bolus Administration for Smooth Emergence From General Sevoflurane Anesthesia
Status: COMPLETED
Conditions: Thyroid Neoplasm
Interventions: DRUG: dexmedetomidine|DRUG: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Technology Delivered Diabetes-Modified Behavioral Activation Treatment
Status: TERMINATED
Conditions: Diabetes Mellitus, Type 2
Interventions: BEHAVIORAL: TECH DM-BAT|BEHAVIORAL: TECH DMBAT Active Comparator|BEHAVIORAL: TECH DMBAT Other
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cytokine Adsorption in Sepsis and Acute Kidney Injury
Status: UNKNOWN
Conditions: Renal Insufficiency or Renal Failure &or End-stage Renal Disease
Interventions: DEVICE: CytoSorb 300 ml device (3804606CE01)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Therapy of Pulmonary Arterial Hypertension (PAH) - Treatment With Sildenafil in Eisenmenger Patients
Status: TERMINATED
Conditions: Pulmonary Arterial Hypertension (PAH)
Interventions: DRUG: Sildenafil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The New Serial Treatment of Temporomandibular Disorders
Status: RECRUITING
Conditions: Temporomandibular Disorder
Interventions: PROCEDURE: Adjust the TMJ Pressure to Normal Value|OTHER: Do not adjust the pressure of TMJ
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Myofascial Relaxation Technique Applied Together With Core Stabilization Trainings on Balance, Pain, Joint Range of Motion and Functionality in Individuals With Chronic Neck Pain
Status: RECRUITING
Conditions: Neck Pain
Interventions: OTHER: Core stability training|OTHER: Core stability training and myofascial relase
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Stem Cells Treatment for the Local Urinary Incontinence After a Radical Prostate Cancer Surgery (HULPURO)
Status: COMPLETED
Conditions: Urinary Incontinence
Interventions: DRUG: Inject of Autologous Adipose-derived stem cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Triumeq in Amyotrophic Lateral Sclerosis
Status: RECRUITING
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DRUG: Dolutegravir, Abacavir and Lamivudine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Descriptive Study of Cardiac Output During Rehydration With Recombinant Human Hyaluronidase in Pediatrics
Status: COMPLETED
Conditions: Dehydration|Cardiac Output|Pediatrics
Interventions: DRUG: Hylenex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Comparison of Image Quality of Coronary Computed Tomography Angiography bEtweeN High concenTRATion and Low concEntration Contrast Agents(CONCENTRATE Trial)
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: PROCEDURE: CT angiography with high concentration contrast agent|PROCEDURE: CT angiography with low concentration contrast agent (320)|PROCEDURE: CT angiography with low concentration contrast agent (270)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Feasibility of 5% Albumin Compared With Balanced Crystalloid, as Intravenous Fluid Resuscitation in Adult Patients With Sepsis, Presenting as an Emergency to Hospital
Status: UNKNOWN
Conditions: Sepsis
Interventions: DRUG: Human albumin|DRUG: Balanced crystalloid solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Different Doses of Neostigmine for Reversal of Moderate Neuromuscular Blockade in Children
Status: UNKNOWN
Conditions: Neuromuscular Blockade|Neuromuscular Block, Residual|Neuromuscular Block Prolonged
Interventions: DRUG: Neostigmine 10 mcg/kg|DRUG: Neostigmine 20 mcg/kg|DRUG: Neostigmine 30 mcg/kg|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Role of Nitric Oxide in Optic Nerve Head Blood Flow Regulation During Experimental Increase of Intraocular Pressure in Healthy Humans
Status: TERMINATED
Conditions: Healthy
Interventions: DRUG: NG-monomethyl-L-arginine (L-NMMA)|DRUG: Phenylephrine|DRUG: Physiological saline solution (as placebo)|DEVICE: Laser Doppler Flowmetry|DEVICE: Goldmann applanation tonometer|DEVICE: Suction cup
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Frequency-time Analysis of Pathological Lung Sounds: Detection and Quantification of Pathological Sounds in Patients With Cystic Fibrosis, Pulmonary Fibrosis or COPD (Chronic Obstructive Pulmonary Disease)
Status: NOT_YET_RECRUITING
Conditions: Pulmonary Fibrosis|Chronic Obstructive Pulmonary Disease|Cystic Fibrosis
Interventions: OTHER: Lung sound recordings
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Gut-brain Axis, Brain Function, and Behaviour.
Status: UNKNOWN
Conditions: Prebiotics|Anxiety|Humans|Magnetic Resonance Imaging|Decision Making|Emotion|Cortisol
Interventions: DIETARY_SUPPLEMENT: Prebiotics|DIETARY_SUPPLEMENT: Maltodextrin (placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: EDIT-301 for Autologous Hematopoietic Stem Cell Transplant (HSCT) in Participants With Transfusion-Dependent Beta Thalassemia (TDT)
Status: RECRUITING
Conditions: Transfusion Dependent Beta Thalassemia|Hemoglobinopathies|Thalassemia Major|Thalassemia Intermedia
Interventions: GENETIC: EDIT-301
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Effects of Delay in the First Bathing Time of Body Temperature and the Rate of Exclusive Breastfeeding
Status: COMPLETED
Conditions: Newborn Hypothermia
Interventions: BEHAVIORAL: Delay first bath
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Haptoglobin Phenotype, Vitamin E and High-density Lipoprotein (HDL) Function in Type 1 Diabetes
Status: COMPLETED
Conditions: Type 1 Diabetes|Heart Disease
Interventions: DIETARY_SUPPLEMENT: Vitamin E|OTHER: Dummy pills
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Self-taken Penile Meatal Swabs for Chlamydia, Gonorrhoea and Mycoplasma Genitalium Detection
Status: UNKNOWN
Conditions: Sexually Transmitted Diseases, Bacterial
Interventions: DEVICE: Aptima-Combo2 and Aptima Mgen
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluating Respiratory Effects of Driving Pressure Guided Mechanical Ventilation Using Electrical Impedance Tomography in Patients Undergoing Robot-Assisted Laparoscopic Radical Prostatectomy
Status: ENROLLING_BY_INVITATION
Conditions: Prostate Cancer|Lung Protective Ventilation|Postoperative Pulmonary Complications
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Multi-parametric Biomarker Development to Predict Malignant Conversion in Patients With Neurofibromatosis Type 1
Status: RECRUITING
Conditions: Neurofibromatosis 1|Malignant Peripheral Nerve Sheath Tumor (MPNST) of Soft Tissue (Diagnosis)|Atypical Neurofibroma
Interventions: DIAGNOSTIC_TEST: Whole Body Magnetic Resonance Imaging
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety, Efficacy, PD of FE203799 in Short Bowel Syndrome on Parenteral Support
Status: COMPLETED
Conditions: Short Bowel Syndrome
Interventions: DRUG: FE203799 GLP-2 analogue|DRUG: FE203799 Placebo GLP-2 analogue|DRUG: FE203799 GLP-2 analogue
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Single Centre Study to Assess the Long-term Performance of the DePuy ASR™ System in Primary Hip Resurfacing Surgery
Status: TERMINATED
Conditions: Rheumatoid Arthritis|Osteoarthritis|Post-traumatic Arthritis|Collagen Disorders|Avascular Necrosis|Nonunion of Femoral Fractures|Congenital Hip Dysplasia|Slipped Capital Femoral Epiphysis
Interventions: DEVICE: DePuy ASR™ Hip System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of a Squatting Assist Device in Patients With Constipation
Status: RECRUITING
Conditions: Constipation
Interventions: DEVICE: Squatting Assist Device|DEVICE: Sham Squatting Assist Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: 177Lu-HTK03170 in mCRPC With PSMA Positive Disease
Status: RECRUITING
Conditions: Metastatic Castration-resistant Prostate Cancer|Prostate Cancer Metastatic|Castrate Resistant Prostate Cancer
Interventions: DRUG: 177Lu HTK03170|DRUG: 68Ga-HTK03149
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Numerical Superiority and Inferiority Compared With Conventional Training on PTK and Executive Functions in Soccer
Status: COMPLETED
Conditions: Decision Making in Soccer Players and Executive Functions
Interventions: BEHAVIORAL: Tactical training in numerical superiority and numerical inferiority|BEHAVIORAL: Conventional training in numerical equality
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Local Anesthesia in Radial Catheterization
Status: UNKNOWN
Conditions: Anesthesia, Local|Coronary Artery Disease|Catheter Site Discomfort|Catheter Site Pain
Interventions: DRUG: Local anesthetic|DRUG: local anaesthetic injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Clinical Trial to Evaluate the Efficacy of Smoking Cessation
Status: COMPLETED
Conditions: Smoking Cessation
Interventions: DRUG: Varenicline|DRUG: Nicotine patches|DRUG: Placebo (nicotine patches)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose:
Clinical trial: Chlorhexidine Vaginal and Infant Wash in Pakistan
Status: COMPLETED
Conditions: Sepsis|Pregnancy
Interventions: PROCEDURE: Chlorhexidine vaginal and infant wash
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Study of Jaktinib Hydrochloride Tablets in Participants With Idiopathic Pulmonary Fibrosis
Status: ACTIVE_NOT_RECRUITING
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: DRUG: Jaktinib Hydrochloride Tablets|DRUG: Jaktinib Hydrochloride Tablets|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Open Pilot Trial of a Mind-body Program for Cardiac Arrest Survivors and Their Caregivers
Status: NOT_YET_RECRUITING
Conditions: Emotional Distress|Cardiac Arrest
Interventions: BEHAVIORAL: Recovering Together after Cardiac Arrest
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, and Efficacy Study of CLL442 in Patients With Cutaneous Squamous Cell Carcinoma in Situ (SCCis)
Status: TERMINATED
Conditions: Cutaneous Squamous Cell Carcinoma in Situ (CSCCis)
Interventions: DRUG: Cutaneous Cream application|DRUG: Placebo Cutaneous Cream application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: FiteBac Hand Sanitizer in the Management of Hand Dermatitis in Adults
Status: COMPLETED
Conditions: Hand Dermatitis
Interventions: OTHER: fiteBac Hand Sanitizer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Trial Of Achieving Healthy Lifestyles In Psych Rehabilitation
Status: COMPLETED
Conditions: Overweight and Obesity
Interventions: BEHAVIORAL: ACHIEVE Intervention|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Alcohol and Gender Effects on Stress Circuit Function
Status: COMPLETED
Conditions: Alcoholism|Stress|Alcohol Dependence
Interventions: DRUG: Citalopram|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Four-week Study of the Safety and Efficacy of NLS-2 (Mazindol Extended Release) in the Treatment of Narcolepsy
Status: COMPLETED
Conditions: Narcolepsy|Excessive Daytime Sleepiness|Cataplexy Narcolepsy
Interventions: DRUG: mazindol extended release|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Fine Motor Skills Training Through Telerehabilitation in Children With Diplegic Cerebral Palsy
Status: COMPLETED
Conditions: Diplegia, Spastic
Interventions: OTHER: Telerehabilitation Program|OTHER: Written Home Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Phase I Trial From GRID 18F-FDG-PET Biological Imaging-guided Intensitymodulated Radiotherapy (BG-IMRT) With Patients With Recurrent or New Head or Neck Tumor in Previously Radiated Area
Status: TERMINATED
Conditions: Head and Neck Tumors
Interventions: RADIATION: GRID radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hyperbaric Oxygen Treatment to Treat Mild Traumatic Brain Injury (mTBI)/Persistent Post-Concussion Syndrome (PPCS)
Status: UNKNOWN
Conditions: Post-Concussion Syndrome|Traumatic Brain Injury
Interventions: DRUG: Hyperbaric Oxygen|DRUG: No Hyperbaric Oxygen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Neoantigen-based Personalized Vaccine Combined With Immune Checkpoint Blockade Therapy in Patients With Newly Diagnosed, Unmethylated Glioblastoma
Status: TERMINATED
Conditions: Glioblastoma
Interventions: BIOLOGICAL: NeoVax|BIOLOGICAL: Nivolumab|BIOLOGICAL: Ipilimumab|PROCEDURE: Research blood draw|PROCEDURE: Leukapheresis for research
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Two Treatments: Pacemaker and Percutaneous Transluminal Septal Ablation for Hypertrophic Cardiomyopathy
Status: COMPLETED
Conditions: Hypertrophic Cardiomyopathy
Interventions: PROCEDURE: pacemaker implantation|PROCEDURE: percutaneous transluminal septal ablation (PTSA)
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Study on Psychoeducation Enhancing Results of Adherence in Schizophrenia
Status: COMPLETED
Conditions: Patient Non-Compliance|Schizophrenia and Related Disorders
Interventions: BEHAVIORAL: Falloon et al. Psychoeducation Program|BEHAVIORAL: Generic Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Psychotherapy for Depressed Mothers of Psychiatrically Ill Children
Status: COMPLETED
Conditions: Depression
Interventions: BEHAVIORAL: Interpersonal Psychotherapy for Mothers (IPT-MOMS)|BEHAVIORAL: Brief Supportive Psychotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Observational Study to Assess Optive MEGA-3 (OM3) on Dry Eye Symptoms and Quality of Life of Adult Participants With Mild to Moderate Dry Eye Disease (DED)
Status: COMPLETED
Conditions: Dry Eye
Interventions: DRUG: Optive MEGA-3 (OM3)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Immunotherapy With NK Cell, Rituximab and Rhu-GMCSF in Non-Myeloablative Allogeneic Stem Cell Transplantation
Status: COMPLETED
Conditions: Lymphoma|Leukemia|Transplantation, Stem Cell|Lymphoid Malignancies|Disorder Related to Transplantation
Interventions: DRUG: GM-CSF|DRUG: Rituximab|BIOLOGICAL: NK Cell Infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Study Using Genomic & Proteomic Profiling to Influence Treatments for Patients With Metastatic Breast Cancer
Status: TERMINATED
Conditions: Metastatic Breast Cancer
Interventions: OTHER: Genomic and Proteomic Profiling
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Strategies for the Treatment of Chronic Hepatitis C in Colombia
Status: UNKNOWN
Conditions: Hepatitis C
Interventions: OTHER: Health care under the strategic purchase-Clinical pathway|OTHER: Usual care process prior strategic purchase-clinical pathway
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Early Access Program Providing HER2/HER3 Bispecific Antibody, MCLA-128, for a Patient With Advanced NRG1-Fusion Positive Solid Tumor
Status: AVAILABLE
Conditions: NRG1 Fusion|Pancreatic Cancer|Non Small Cell Lung Cancer|Solid Tumor, Unspecified, Adult|Prostate Cancer|Head and Neck Cancer|Colorectal Cancer|Breast Cancer|Cholangiocarcinoma|Renal Cell Carcinoma|Unknown Primary Tumors
Interventions: DRUG: MCLA-128
Study Type: EXPANDED_ACCESS
Clinical trial: A Study to Assess if Mirikizumab is Effective and Safe Compared to Secukinumab and Placebo in Moderate to Severe Plaque Psoriasis (OASIS-2)
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: Mirikizumab|DRUG: Placebo|DRUG: Secukinumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Quality of Life Study for Sickle Cell Patients Treated With Jobelyn (Sorghum Bicolor Extract)
Status: UNKNOWN
Conditions: Other Sickle-cell Disorders With Crisis, Unspecified
Interventions: DIETARY_SUPPLEMENT: Folic Acid + Paludrine + Jobelyn (500mg)|DRUG: Folic Acid + Paludrine + Jobelyn (250mg)|DIETARY_SUPPLEMENT: Folic Acid + Paludrine + Jobelyn (2mg)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Feasibility and Safety of Instruments in Transanal Total Mesorectal Excision (TaTME) for Rectal Cancer
Status: UNKNOWN
Conditions: Postoperative Complications
Interventions: DEVICE: TaTME with CS-Compact (GelPoint pathway)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assess the Effectiveness of Atomoxetine in Children With Fetal Alcohol Syndrome and ADD/ADHD
Status: COMPLETED
Conditions: Fetal Alcohol Syndrome|Attention Deficit Disorder With Hyperactivity (ADHD)|Attention Deficit Disorder (ADD)
Interventions: DRUG: Strattera|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT