pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Blood-borne Infection Screening in an Afghan Antenatal Population
Status: COMPLETED
Conditions: Viral Hepatitis B|Contraception|Breast Feeding, Exclusive|Effects of; Lack of Care of Infants
Interventions: BEHAVIORAL: Concentrated postpartum counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study to Evaluate the Safety, PK and PD of VIS171 in Participants (Healthy and With Autoimmune Disease)
Status: TERMINATED
Conditions: Autoimmune Diseases
Interventions: DRUG: VIS171|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radiation Therapy After Lumpectomy in Treating Women With Ductal Carcinoma in Situ or Invasive Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: PROCEDURE: adjuvant therapy|PROCEDURE: conventional surgery|RADIATION: intraoperative radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MIRACLE of LIFE Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Preterm Labor|Preterm Birth|Preterm Birth Complication|Preterm Premature Rupture of Membrane|Preeclampsia|HELLP|Gestational Hypertension|Gestational Diabetes Mellitus in Pregnancy|Small for Gestational Age at Delivery|Intrauterine Growth Restriction
Interventions: DIAGNOSTIC_TEST: Mirvie Predictive Test for Adverse Pregnancy Outcomes
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pemetrexed and Cisplatin in Treating Patients With Advanced, Persistent, or Recurrent Cervical Cancer
Status: COMPLETED
Conditions: Cervical Cancer
Interventions: DRUG: cisplatin|DRUG: pemetrexed disodium
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Different Modes of Ventilation During Cardiopulmonary Bypass
Status: COMPLETED
Conditions: Postoperative Pulmonary Dysfunction
Interventions: DEVICE: Volume controlled ventilation|DEVICE: Pressure controlled ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Robotic Natural Orifice Specimen Extraction Surgery Compared to Robotic Assisted Surgery for Median Rectal Cancer
Status: ENROLLING_BY_INVITATION
Conditions: Natural Orifice Specimen Extraction Surgery|Middle Rectal Cancer|Robotic|Short-term Outcomes
Interventions: PROCEDURE: robotic natural orifice specimen extraction surgery|PROCEDURE: robotic transabdominal specimen extraction surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Shared Care Rehabilitation After Acute Coronary Syndrome
Status: COMPLETED
Conditions: Acute Coronary Syndrome|Myocardial Ischemia|Acute Myocardial Infarction: Rehabilitation Phase
Interventions: BEHAVIORAL: Shared Care model
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Assess the Efficacy of 3 Months of Latanoprost Treatment in Reducing the Intraocular Pressure in Patients With Ocular Hypertension or Open-angle Glaucoma
Status: COMPLETED
Conditions: Glaucoma, Open-Angle|Ocular Hypertension
Interventions: DRUG: Latanoprost
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigating Gains in Neurocognition in an Intervention Trial of Exercise
Status: COMPLETED
Conditions: Healthy|Cognitive Function 1, Social
Interventions: BEHAVIORAL: 150 Minutes Week|BEHAVIORAL: 225 Minutes Week|BEHAVIORAL: Stretch and Tone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Optimising Molecular Radionuclide Therapy
Status: COMPLETED
Conditions: Neuroendocrine Tumors|Hyperthyroidism|Thyroid Cancer|Thyroid Carcinoma
Interventions: DIAGNOSTIC_TEST: Nuclear Medicine whole-body|DIAGNOSTIC_TEST: SPECT/CT imaging.|DIAGNOSTIC_TEST: PET/CT imaging.|DEVICE: Patient-led radiation monitor (SELFIE)|DIAGNOSTIC_TEST: LAB TEST
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Assess the Efficacy and Safety of Salix Probiotic Blend in Participants With Functional Gastrointestinal Disturbances
Status: COMPLETED
Conditions: Functional Gastrointestinal Disorders
Interventions: DIETARY_SUPPLEMENT: Salix Probiotic Blend
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Preoperative Carbohydrate Load and Intraoperative w3-PUFA in CAGB Surgery
Status: COMPLETED
Conditions: Atrial Fibrillation Rapid|Postoperative Complications
Interventions: DIETARY_SUPPLEMENT: CHO (carbohydrate)|DRUG: intravenous w-3 PUFA|OTHER: CHO (carbohydrate) plus intravenous w3-PUFA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Trial to Assess the Efficacy of F598 in Preventing an Experimental Urethral Infection With N. Gonorrhoeae in Healthy Males
Status: TERMINATED
Conditions: Neisseria Gonorrhoeae
Interventions: DRUG: 1 mg/kg single infusion of F598|DRUG: 3 mg/kg single infusion of F598|DRUG: 10 mg/kg single infusion of F598
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate Infliximab in Subjects With Moderate-to-Severe Psoriasis Not Responding to Standard or Biologic Therapy (Study P04612)
Status: COMPLETED
Conditions: Psoriasis
Interventions: BIOLOGICAL: Infliximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Long Term Study of STN1012600 in Subjects With Open Angle Glaucoma or Ocular Hypertension
Status: COMPLETED
Conditions: Open Angle Glaucoma, Ocular Hypertension
Interventions: DRUG: STN1012600 ophthalmic solution 0.002%|DRUG: STN1012600 ophthalmic solution 0.002%|DRUG: STN1012600 ophthalmic solution 0.002% and Timolol ophthalmic solution 0.5%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diode Laser Study for Periodontal Maintenance Patients
Status: COMPLETED
Conditions: Periodontal Diseases|Periodontitis, Apical, Chronic Nonsuppurative|Suppuration of Gingival Crevice
Interventions: PROCEDURE: Scaling and Root Planing|PROCEDURE: Diode Laser + Scaling and Root Planing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Impact of Artificial Intelligence (AI) on Adenoma Detection During Colonoscopy in FIT+ Patients.
Status: COMPLETED
Conditions: Polyp of Colon
Interventions: DEVICE: Artificial Intelligence System (CAD EYE, Fujifilm Co.)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: A Study of Anlotinib in Combination With Docetaxel Versus Docetaxel Alone in Participants With Advanced NSCLC
Status: UNKNOWN
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: Anlotinib combined Docetaxel|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Supplemental Enteral Protein in Critical Illness
Status: COMPLETED
Conditions: Nutrition Disorder|Trauma|Critical Illness
Interventions: DIETARY_SUPPLEMENT: Protein supplementation|OTHER: Standard enteral nutrition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Validation of the 18 kiloDalton Translocator Protein (TSPO) as a Novel Neuroimmunodulatory Target
Status: RECRUITING
Conditions: Multiple Sclerosis
Interventions: DRUG: XBD173|DRUG: Etifoxine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Holographic Screens as a Replacement of Monitors During GI Endoscopies
Status: RECRUITING
Conditions: Gastrointestinal Diseases
Interventions: DEVICE: Endoscopy guided by mixed reality (HoloLens2TM) (HXtend™ software)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: DS8201a and Pembrolizumab in Participants With Locally Advanced/Metastatic Breast or Non-Small Cell Lung Cancer
Status: RECRUITING
Conditions: Breast Cancer|Non-small Cell Lung Carcinoma
Interventions: DRUG: Trastuzumab deruxtecan (DS-8201a)|DRUG: Trastuzumab deruxtecan (DS-8201a)|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Study of Lenalidomide to Evaluate the Efficacy in Japanese Patients With Newly Diagnosed Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Lenalidomide|DRUG: dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Long-term Extension Study to Evaluate Safety, Tolerability, and Efficacy of AL002 in Alzheimer's Disease
Status: RECRUITING
Conditions: Alzheimer's Disease
Interventions: DRUG: AL002
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of an A1-Adenosine Receptor Agonist to Slow Heart Rate in Atrial Fibrillation
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DRUG: DTI-0009
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Phase Ib Clinical Study for rhTPO in the Treatment of Thrombocytopenia in Patients With Chronic Liver Disease
Status: UNKNOWN
Conditions: Liver Disease Chronic|Thrombocytopenia
Interventions: DRUG: recombinant human thrombopoietin injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Research Study to Evaluate MK0653 (Ezetimibe) and Simvastatin, Given Together and Alone, on Intestinal Absorption of Cholesterol (0653-050)(COMPLETED)
Status: COMPLETED
Conditions: Cholesterol
Interventions: DRUG: ezetimibe|DRUG: Comparator: Placebo (unspecified)|DRUG: simvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effects of Fiber on Appetite and Digestion Hormones
Status: COMPLETED
Conditions: Psychological Phenomena and Processes|Nutrition Physiological Phenomena
Interventions: DIETARY_SUPPLEMENT: No fiber|DIETARY_SUPPLEMENT: Low GI high fiber viscous meal|DIETARY_SUPPLEMENT: Low GI high fiber non-viscous
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of Two Anaesthetics on Brain During Brain Tumour Surgery
Status: COMPLETED
Conditions: Inflammation
Interventions: DRUG: Propofol|DRUG: Sevoflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: LE Gel for the Treatment of Ocular Inflammation and Pain Following Cataract Surgery
Status: COMPLETED
Conditions: Cataract|Pain|Ocular Inflammation
Interventions: DRUG: Loteprednol Etabonate Ophthalmic Gel dosed TID|DRUG: Loteprednol Etabonate Ophthalmic Gel dosed BID|DRUG: Vehicle Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: JUNIPER: A Phase 2 Study to Evaluate the Safety, Biological Activity, and PK of ND-L02-s0201 in Subjects With IPF
Status: COMPLETED
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: DRUG: ND-L02-s0201 (Low Dose)|DRUG: ND-L02-s0201 (High Dose)|OTHER: Other: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Repaglinide and Metformin Combination Tablet Versus Repaglinide and Metformin as Separate Tablets in Healthy Volunteers
Status: COMPLETED
Conditions: Diabetes|Healthy
Interventions: DRUG: repaglinide and metformin combination tablet|DRUG: repaglinide and metformin combination tablet|DRUG: repaglinide|DRUG: metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ketamine for Analgesia After Cesarean Section
Status: COMPLETED
Conditions: Cesarean Section|Postoperative Pain
Interventions: DRUG: 0.25 mg/kg of Ketamine|DRUG: 20ml of normal saline solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Prospective Study Comparing the Efficacy of Laminoplasty and Laminectomy With Fusion for Ossification of the Posterior Longitudinal Ligament With High Occupation Rate in Cervical Spine
Status: COMPLETED
Conditions: Ossification of the Posterior Longitudinal Ligament
Interventions: PROCEDURE: Laminoplasty|PROCEDURE: Laminectomy With Fusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Follow-up Gene Therapy Trial for the Treatment of X-linked Retinitis Pigmentosa Associated With Variants in the RPGR Gene
Status: ACTIVE_NOT_RECRUITING
Conditions: X-Linked Retinitis Pigmentosa
Interventions: BIOLOGICAL: Genetic: AAV5-hRKp.RPGR Intermediate Dose|BIOLOGICAL: Genetic: AAV5-hRKp.RPGR Low Dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Role of Oxytocin in Modulating the Effects of Social Feedback on Achieving Personal Goals
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: oxytocin treatment|DRUG: placebo treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Extension Study of the Efficacy and Safety of Deferasirox Treatment in Beta-thalassemia Patients With Transfusional Hemosiderosis (Study Amended to 2-year Duration)
Status: COMPLETED
Conditions: Beta-thalassemia Major|Hemosiderosis|Iron Overload|Rare Anemia
Interventions: DRUG: Deferasirox
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: "Facemask Use During High-intensity Interval Exercise in Temperate and Hot Environments"
Status: COMPLETED
Conditions: Hypoxemia|Physiological Stress
Interventions: DEVICE: High-intensity interval exercise with surgical face mask in a temperate environment|DEVICE: High-intensity interval exercise with surgical face mask in a hot environment|OTHER: High-intensity interval exercise without using a surgical face mask in a hot environment|OTHER: High-intensity interval exercise without using a surgical face mask in a temperate environment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study To Evaluate PF-00915275 In Subjects With Type 2 Diabetes Mellitus For 4-Weeks
Status: TERMINATED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: PF-00915275
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Growing up With the Young Endocrine Support System (YESS!)
Status: NOT_YET_RECRUITING
Conditions: Congenital Adrenal Hyperplasia|Hypogonadotropic Hypogonadism|Growth Hormone Deficiency|Combined Pituitary Hormone Deficiency|Turner Syndrome|Klinefelter Syndrome|Addison's Disease|Androgen Insensitivity Syndrome|Thyroid Dysgenesis
Interventions: DEVICE: YESS! game|DEVICE: Snake '97|OTHER: Transition-toolkit
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: To Assess Efficacy and Safety of Oral Reparixin in Patients With Fatigue and Locally Advanced / Metastatic Breast Cancer
Status: WITHDRAWN
Conditions: Fatigue|Locally Advanced or Metastatic Breast Cancer
Interventions: DRUG: Reparixin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: AFS Compared to AHC in Treatment of Necrotizing Fasciitis NF
Status: RECRUITING
Conditions: Necrotizing Fasciitis
Interventions: DEVICE: Acellular Fish Skin Graft (AFS) with Standard of Care Negative Pressure Wound Therapy (NPWT)|OTHER: Acellular Human Cadaver (AHC) with Standard of care Negative Pressure Wound Therapy (NPWT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: WHENII - Early Response Evaluation With FDG-PET/CT and Liquid Biopsy in Patients With NSCLC
Status: UNKNOWN
Conditions: Non Small Cell Lung Cancer|Circulating Tumor Cell|Circulating Tumor DNA
Interventions: DEVICE: PET/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Fixation of Displaced Midshaft Clavicular Fractures in Adults by Intramedullary Elastic Rod
Status: UNKNOWN
Conditions: Clavicular Fracture
Interventions: PROCEDURE: Percutaneous intramedullary fixation of displaced midshaft clavicular fractures .
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Erector Spina Plane Block and Paravertebral Block on Early Postoperative Pulmonary Function Test Parameters
Status: RECRUITING
Conditions: Respiratory Function Loss|Pain, Postoperative|Opioid Use
Interventions: PROCEDURE: Erector Spinae Plane Block (ESP)|PROCEDURE: Paravertebral Block (PVB)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Dexmedetomidine Versus Ketofol for Moderate Sedation in Endoscopic Retrograde Cholangiopancreatography
Status: COMPLETED
Conditions: Sedation
Interventions: DRUG: Dexmedetomidine|DRUG: Ketofole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Alcohol Research in HIV: Relapse Prevention
Status: RECRUITING
Conditions: HIV|Alcohol Use Disorder
Interventions: BEHAVIORAL: Relapse Prevention Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Evaluation of a New Naloxone Nasal Swab, Naloxone Nasal Spray, and Intramuscular Naloxone Injection in Healthy Volunteers
Status: COMPLETED
Conditions: Opioid Overdose
Interventions: DRUG: IM Naloxone Injection|DRUG: Naloxone Nasal Spray|DRUG: Naloxone Nasal Swab|DRUG: Naloxone Nasal Swab|DRUG: Naloxone Nasal Swab|DRUG: Naloxone Nasal Swab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Optimisation of ASthma In Those With Uncontrolled Symptoms (OASIS)
Status: COMPLETED
Conditions: Asthma|Asthma Attack|Asthma Persistent|Covid19
Interventions: DEVICE: ReferID
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Pediatric Study of a Plerixafor Containing Regimen In Second Allogeneic Stem Cell Transplantation
Status: COMPLETED
Conditions: Acute Lymphoblastic Leukemia|Acute Myeloid Leukemia|Chronic Myeloid Leukemia|Myelodysplastic Syndrome|Non-Hodgkin's Lymphoma
Interventions: DRUG: Plerixafor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Safety and Efficacy of Using EndyMed Pro Skin Treatment System for Skin Wrinkle Treatment on Body Areas
Status: COMPLETED
Conditions: Skin Aging|Skin Wrinkling
Interventions: DEVICE: Device: EndyMed Pro System for Skin Tightening
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of HFB301001 in Adult Patients With Advanced Solid Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Soft Tissue Sarcoma|Renal Cell Carcinoma|Uterine Carcinosarcoma|Hepatocellular Carcinoma|Head and Neck Squamous Cell Carcinoma|Melanoma
Interventions: DRUG: HFB301001
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Selective Estrogen Receptor Modulators for Women of Child-bearing Age With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder
Interventions: DRUG: Raloxifene hydrochloride|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Perineural Dexamethasone for Continuous Femoral Nerve Block
Status: COMPLETED
Conditions: Total Knee Arthroplasty
Interventions: PROCEDURE: dexamethasone group|PROCEDURE: sham group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The BEACON Study (Breast Cancer Outcomes With NKTR-102)
Status: COMPLETED
Conditions: Locally Recurrent Breast Cancer|Metastatic Breast Cancer
Interventions: DRUG: NKTR-102|DRUG: Treatment of Physician's Choice (TPC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multi-centered Feedback and Education Intervention Designed to Reduce Inappropriate Transthoracic Echocardiograms
Status: UNKNOWN
Conditions: CARDIOVASCULAR DISEASES
Interventions: BEHAVIORAL: Education and Feedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Clinical Trial of Approaches to Prostate Cancer Surgery
Status: RECRUITING
Conditions: Prostate Cancer
Interventions: PROCEDURE: Robot-assisted radical prostatectomy (RP)|PROCEDURE: Pelvic fascia-sparing robot-assisted radical prostatectomy (PFS-RP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Legs Dysmetria in Total Hip Replacement: Does Hip Approacches and Navigation Decrease the Risk?
Status: RECRUITING
Conditions: Hip Osteoarthritis
Interventions: DEVICE: Velys hip navigation|PROCEDURE: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Systolic Ankle arteriaL Pressure and Transcutaneous oximetrY During a TURTLE Test in Athletes
Status: COMPLETED
Conditions: Iliac Kinking
Interventions: DIAGNOSTIC_TEST: Transcutaneous oximetry
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Impact of 3D Intraoral Scanning on Postsurgical Evaluation of Mandibular Third Molar Surgery
Status: COMPLETED
Conditions: Third Molar Surgery|Impacted Third Molar Tooth
Interventions: DEVICE: Third molar surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Interest of Tecartherapy on a Painful Caesarean Section Scar: a Randomized Clinical Trial.
Status: RECRUITING
Conditions: Cesarean Section|Postpartum|Abdominal Pain|Morbidity
Interventions: DEVICE: Winback® on|DEVICE: Winback® off|BEHAVIORAL: self-massage of the scar
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Efficacy and Safety of HL151 Versus Talion Tab. in Pruritus Cutaneus
Status: COMPLETED
Conditions: Pruritus
Interventions: DRUG: HL151|DRUG: Talion Tab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: McGrath Mac VideoLaryngoscope vs the Macintosh Laryngoscope
Status: TERMINATED
Conditions: Tracheal Intubation
Interventions: DEVICE: Macintosh laryngoscope|DEVICE: McGrath Mac videolaryngoscope
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Tolerability, Safety and Immunogenicity Trial of the Flu-M Quadro, Tetravalent Inactivated Split Influenza Vaccine
Status: COMPLETED
Conditions: Influenza|Influenza, Human|Influenza Viral Infections|Vaccine Reaction|Vaccination; Infection
Interventions: BIOLOGICAL: Influenza vaccine [inactivated]|BIOLOGICAL: Influenza vaccine [inactivated]|BIOLOGICAL: Influenza vaccine [inactivated]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study Evaluating the Safety and Efficacy of Inhaled AP01 in Participants With Progressive Pulmonary Fibrosis
Status: RECRUITING
Conditions: Progressive Pulmonary Fibrosis
Interventions: DRUG: AP01|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Oral Colchicine in Prevention of Proliferative Vitreoretinopathy in Rhegmatogenous Retinal Detachment
Status: UNKNOWN
Conditions: Rhegmatogenous Retinal Detachment
Interventions: DRUG: colchicine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Effects of Progressive Negative Energy Balance on Glucose Tolerance, Insulin Sensitivity, and Beta-cell Function
Status: UNKNOWN
Conditions: Insulin Sensitivity|Glucose Intolerance|Insulin Resistance|Energy Supply; Deficiency
Interventions: BEHAVIORAL: Negative energy balance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Molecular and Whole-body MR Imaging in Lymphomas
Status: COMPLETED
Conditions: Lymphoma|Hodgkin Disease|Lymphoma, Non-Hodgkin
Interventions: OTHER: 68Ga-DOTANOC PET/CT; Diffusion weighted MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The MARVIN Chatbots to Provide Information for Different Health Conditions
Status: RECRUITING
Conditions: HIV Infections|Breast Cancer|Pediatric Emergency Medicine
Interventions: OTHER: MARVIN|OTHER: MARVIN-Pharma|OTHER: MARVINA|OTHER: MARVIN-CHAMP
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: All-poly Versus Metal-backed
Status: ACTIVE_NOT_RECRUITING
Conditions: Osteoarthritis
Interventions: DEVICE: Triathlon PS Knee System with all-polyethylene tibial components|DEVICE: Triathlon PS Knee System with metal-backed modular components
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: Effects of Su Jok Therapy on Pain, Fatigue, Nausea-Vomiting and Spiritual Well-Being
Status: NOT_YET_RECRUITING
Conditions: Cancer|Chemotherapy
Interventions: OTHER: Su jok seed therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Clinical Effects of Exercise Program Added to Pulmonary Rehabilitation in Patients With Cystic Fibrosis
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: OTHER: Active cycle of breathing techniques (ACBT)|OTHER: Postural Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Examine the Efficacy, Safety and Tolerability, and Pharmacokinetics of Exenatide Once Monthly Suspension
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: exenatide once weekly|DRUG: exenatide once monthly suspension|DRUG: exenatide once monthly suspension|DRUG: exenatide once monthly suspension
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transcranial Direct Current Stimulation (tDCS) to Improve Fatigue and Cognitive Function
Status: COMPLETED
Conditions: Breast Cancer|Fatigue
Interventions: OTHER: transcranial direct current stimulation|OTHER: sham transcranial direct current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Vitamin D3 Substitution in Vitamin D Deficient Kidney Transplant Recipients
Status: UNKNOWN
Conditions: Kidney Transplantation|Vitamin D Deficiency|Renal Osteodystrophy
Interventions: DRUG: Cholecalciferol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Can we Reduce Hospital Attendance Without Compromising Care by the Use of Telephone Consultation
Status: COMPLETED
Conditions: Asthma|COPD|Sleep Apnea Syndromes|Interstitial Lung Diseases|Bronchiectasis
Interventions: PROCEDURE: Telephone consultation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Evaluation of Pharmacokinetic Interaction of Indacaterol With Ketoconazole in Healthy Adult Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Indacaterol (QAB149)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of Topical Latanoprost Compared With Topical Brimonidine in the Treatment of the Primary Open Angle Glaucoma
Status: COMPLETED
Conditions: To See the Safety and Efficacy of the Topical Latanoprost Compared With Topical Brimonidine in the Treatment of the Primary Open Angle Glaucoma Patients
Interventions: DRUG: Drugs, Investigational
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Immunologic Diagnostic Blood Test in Predicting Side-Effects in Patients Undergoing a Donor Stem Cell Transplant for Hematologic Cancer or Other Diseases
Status: TERMINATED
Conditions: Chronic Myeloproliferative Disorders|Graft Versus Host Disease|Infection|Leukemia|Lymphoma|Multiple Myeloma and Plasma Cell Neoplasm|Myelodysplastic Syndromes|Myelodysplastic-Myeloproliferative Diseases|Neuroblastoma|Therapy-related Toxicity
Interventions: BIOLOGICAL: immunosuppressive therapy|OTHER: immunological diagnostic method|PROCEDURE: allogeneic hematopoietic stem cell transplantation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Topical Hyaluronic Acid and Recurrent Aphthous Stomatitis.
Status: COMPLETED
Conditions: Recurrent Aphthous Stomatitis
Interventions: DRUG: Hyaluronic acid in the form of hyaluronan sodium 25 mg/100 ml as a mouthwash
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CARMEDAS: Cost-Effectiveness Analysis of Imaging Strategies in Symptomatic Carotid Stenosis
Status: UNKNOWN
Conditions: Carotid Stenosis
Interventions: PROCEDURE: contrast-enhanced magnetic resonance angiography
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Clinical Trial of Dental Device Cemented With Polymethyl Methacrylate (PMMA) Bone Cement
Status: RECRUITING
Conditions: Edentulism
Interventions: DEVICE: A dental device made of zirconia. This is a new invention and does not exist generically. The given generic name of the invention (dental device) is "Dantya Nikhan".
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ipilimumab, Maraviroc and Nivolumab in Advanced Metastatic Colorectal and Pancreatic Cancer the LUMINESCENCE Trial
Status: COMPLETED
Conditions: Colorectal Cancer Metastatic|Pancreatic Cancer Metastatic
Interventions: COMBINATION_PRODUCT: Nivolumab plus Ipilimumab plus Maraviroc
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testing the Efficacy of 100mg Vitamin-B6 Daily for Sensory Reactivity in Autism
Status: NOT_YET_RECRUITING
Conditions: Autism
Interventions: DIETARY_SUPPLEMENT: Pyridoxal 5'-Phosphate (100 mg)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Effectiveness of Giving Indinavir Plus Stavudine Plus Lamivudine to HIV-Infected Children
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Indinavir sulfate|DRUG: Lamivudine|DRUG: Stavudine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: First Research Study to Look at How Two Medicines, NNC0480-0389 and Semaglutide, Work Together in Healthy People, in People With High Body Weight and in People With Diabetes
Status: COMPLETED
Conditions: Healthy Volunteers|Overweight|Obesity|Diabetes Mellitus, Type 2
Interventions: DRUG: NNC0480-0389|DRUG: Semaglutide|DRUG: Placebo (NNC0480-0389)|DRUG: Placebo (semaglutide)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Novel TBI Free Conditioning Protocol for Haploidentical Transplant in Acquired Aplastic Anemia:
Status: UNKNOWN
Conditions: Aplastic Anemia Idiopathic
Interventions: DRUG: Haploidentical HSCT using TBI free regimen, ''ATG'' with ''Post transplant cyclophosphamide''
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Everolimus and Whole-Brain Radiation Therapy in Treating Patients With Brain Metastasis From Non-Small Cell Lung Cancer
Status: TERMINATED
Conditions: Lung Cancer|Metastatic Cancer
Interventions: DRUG: RAD001|RADIATION: whole-brain radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Intra-articular Stromal Vascular Fraction Injection on Clinical Symptoms and Cartilage Health in Osteoarthritic Knees
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: PROCEDURE: Intra-articular Stromal Vascular Fraction Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: XEN1101 for Major Depressive Disorder
Status: RECRUITING
Conditions: Major Depressive Disorder
Interventions: DRUG: XEN1101|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Two Different Dosages of Ethinyl-estradiol in Association With Drospirenone in Women With Polycystic Ovary Syndrome.
Status: COMPLETED
Conditions: Polycystic Ovary Syndrome|Estro-progestin Drugs
Interventions: DRUG: 3 mg drospirenone and 20 µg ethinyl-estradiol|DRUG: 3 mg drospirenone and 30 µg ethinyl-estradiol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BCG + MMC: Adding Mitomycin C to BCG in High-risk, Non-muscle-invasive Bladder Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Transitional Cell Carcinoma|Transurethral Resection
Interventions: BIOLOGICAL: Bacillus Calmette-Guerin Vaccine Intravesical|DRUG: Mitomycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness and Safety of Ramipril Alone Compared With Telmisartan Alone and in Combination With Ramipril in Patients at High Risk for Cardiovascular Events. Patients Intolerant to Ramipril Were Entered in TRANSCEND, Telmisartan Compared to Placebo.
Status: COMPLETED
Conditions: Cardiovascular Diseases
Interventions: DRUG: Telmisartan|DRUG: Combination of Telmisartan and Ramipril|DRUG: Ramipril
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: |Primary Purpose: PREVENTION
Clinical trial: Adjuvant Radiotherapy in Patients With Early Endometrial Cancer
Status: NOT_YET_RECRUITING
Conditions: Endometrial Cancer|Pathology|Radiotherapy
Interventions: RADIATION: vaginal brachytherapy/pelvic external beam radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Mobile Health Applications on Symptom Control, Self-efficacy and Chronic Disease Management in COPD
Status: RECRUITING
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DEVICE: mKOAH application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: The Efficacy of Prednisone and Combination Therapy With Methylprednisolone and Cyclophosphamide on IMN in Stage I.
Status: TERMINATED
Conditions: Idiopathic Membranous Nephropathy
Interventions: DRUG: Prednisone|DRUG: MP and CTX
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective, International Monosyn® Quick - Non Interventional Study
Status: COMPLETED
Conditions: Pediatric and Adult: Mucosal Closure in Facial and Oral Surgery|Pediatric and Adult: Skin Closure (Dermal Sutures)|Women: Episiotomy|Pediatric: Urological Interventions (Circumcision, Phimosis Etc.)
Interventions: DEVICE: Monosyn® Quick
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Spasticity-correcting Hand Surgery for Spasticity Related Symptoms
Status: UNKNOWN
Conditions: Spasticity, Muscle|Spinal Cord Injuries|Traumatic Brain Injury|Stroke|Upper Extremity Paresis
Interventions: PROCEDURE: Hand surgery and intensive rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Sequential Method Determination of Oxycodone for Thoracoscope Surgery Median Effective Dose of Acute Pain Treatment
Status: NOT_YET_RECRUITING
Conditions: Oxycodone|Thoracoscopic Lobectomy|Acute Postoperative Pain
Interventions: DRUG: Oxycodone will be administered intravenously in the group 1
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: This Study Tests the Effect of Risankizumab on the Metabolism in the Liver of Five Additional Drugs to Study Possible Drug Interactions in Patients With Psoriasis With or Without Psoriatic Arthritis
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: Caffeine|DRUG: Warfarin|DRUG: Omeprazole|DRUG: Metoprolol|DRUG: Midazolam|DRUG: Risankizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Dietary Nitrate Intake on Cardiovascular Performance in Response to Hand Grip Test in Bodybuilders
Status: RECRUITING
Conditions: Steroid Abuse|Cardiovascular Abnormalities
Interventions: DIETARY_SUPPLEMENT: Beetroot juice rich in nitrate|DIETARY_SUPPLEMENT: Beetroot juice depleted in nitrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study to Evaluate the Safety and Efficacy of BF-200 ALA (Ameluz®) and BF-RhodoLED® in the Treatment of Superficial Basal Cell Carcinoma (sBCC) With Photodynamic Therapy (PDT).
Status: ACTIVE_NOT_RECRUITING
Conditions: Superficial Basal Cell Carcinoma
Interventions: COMBINATION_PRODUCT: Photodynamic therapy (PDT) (ALA-PDT, Ameluz®-PDT)|COMBINATION_PRODUCT: Placebo Photodynamic therapy (PDT) (vehicle to BF-200 ALA containing no active ingredient)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hepatic Arterial Infusion With Floxuridine and Dexamethasone in Combination With Intravenous Oxaliplatin Plus Irinotecan in Patients With Unresectable Hepatic Metastases From Colorectal Cancer
Status: COMPLETED
Conditions: Colon Cancer|Rectal Cancer
Interventions: DRUG: Floxuridine, Oxaliplatin, CPT-11|DRUG: Floxuridine, Oxaliplatin, CPT-11
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cytokine-Induced Memory-Like Natural Killer Cells (CIML-NK) for Relapsed & Refractory Acute Myeloid Leukemia (AML)
Status: RECRUITING
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: CIML-NK Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Silver Diamine Fluoride in Preventing Occlusal Caries in Primary Teeth
Status: UNKNOWN
Conditions: Dental Caries in Children
Interventions: DRUG: silver diamine fluoride|DRUG: sodium fluoride varnish|OTHER: tonic water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety, Reactogenicity and Immunogenicity Study of ReCOV
Status: COMPLETED
Conditions: Covid19
Interventions: BIOLOGICAL: Recombinant two-component COVID-19 vaccine (CHO cell)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: ACTive Exoskeleton for Unilaterally-Assisted Locomotion (ACTUAL)
Status: COMPLETED
Conditions: Stroke Sequelae|Gait, Hemiplegic
Interventions: DEVICE: Exoskeleton stroke group
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Incisionless Suture Plications in a POSE2.0 Interventional Randomized Obesity Study
Status: NOT_YET_RECRUITING
Conditions: Obesity
Interventions: DEVICE: POSE2.0 procedure with g-Cath EZ Delivery Catheter with Snowshoe Suture Anchors
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacogenetic-Guided Antidepressant Prescribing in Adolescents
Status: RECRUITING
Conditions: Depression in Adolescence
Interventions: OTHER: Pharmacogenetic-guided dosing|OTHER: GLAD-PC guided dosing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Real-World Study of Neoadjuvant/Conversion Therapy for Locally Advanced or Metastatic Gastric Cancer
Status: NOT_YET_RECRUITING
Conditions: Gastric Cancer
Interventions: COMBINATION_PRODUCT: fruquintinib combined with immune checkpoint inhibitors and chemotherapy|COMBINATION_PRODUCT: fruquintinib combined with immune checkpoint inhibitors and chemotherapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: NMDA Receptor Modulation for Hyperarousal in PTSD
Status: COMPLETED
Conditions: Depression|Post Traumatic Stress Disorder
Interventions: DRUG: Lanicemine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Application of New Restraint Instruments in Safety Management of Patients After Cardiac Surgery
Status: NOT_YET_RECRUITING
Conditions: After Cardiac Surgery
Interventions: DEVICE: Research on the application of novel restraint devices in postoperative patient safety management in cardiac surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Iloprost for Prevention of Contrast-Mediated Nephropathy in High-Risk Patients Undergoing Coronary Angiography and/or Intervention
Status: COMPLETED
Conditions: Renal Insufficiency, Chronic|Coronary Angiography|Angioplasty, Transluminal, Percutaneous Coronary
Interventions: DRUG: Iloprost|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION