pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Carotid Stenosis
Interventions: PROCEDURE: Carotid endarterectomy (CEA)|DEVICE: Carotid Stenting (CAS)|OTHER: Intensive Medical Management - no CEA|OTHER: Intensive Medical Management - no CAS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Impact of Manikin Training on Airtraq Avant Learning Curve in Predicted Difficult Airways
Status: TERMINATED
Conditions: Education|Training|Manikin
Interventions: OTHER: Preclinical Manikin Training|OTHER: Inservice Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Pharmacokinetics (PK) Study of Gepotidacin (GSK2140944) in Adult Subjects With Varying Degrees of Hepatic Impairment and in Matched Control Subjects With Normal Hepatic Function
Status: COMPLETED
Conditions: Infections, Bacterial
Interventions: DRUG: Gepotidacin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Modes of Respiratory Physiotherapy in Cardio-thoracic Surgical Patients
Status: COMPLETED
Conditions: Postoperative; Dysfunction Following Cardiac Surgery|Postoperative; Dysfunction Following Lung Surgery
Interventions: OTHER: Chest Physiotherapy|DEVICE: Post-therapy lung volume measurements
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: PEG-rhG-CSF in Patients With Non-Hodgkin Lymphoma Receiving Chemotherapy to Prevent Neutropenia
Status: UNKNOWN
Conditions: Lymphoma,Non-Hodgkin
Interventions: DRUG: rhG-CSF regimen|DRUG: Pegylated rhG-CSF regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: NYULMC CareSmarts Pilot
Status: COMPLETED
Conditions: Diabetes|Type 2 Diabetes (T2D)
Interventions: BEHAVIORAL: CareSmarts Mobile Health Diabetes Program|BEHAVIORAL: Standard of Care Reminders and Self Assessments
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Oral DS107 in Moderate to Severe Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: Oral DS107|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of infLuenza vaccInation After Myocardial INfArction on Cardiac inflammaTory responsE
Status: RECRUITING
Conditions: Acute Myocardial Infarction|Cardiovascular Diseases|Inflammatory Response
Interventions: BIOLOGICAL: Influenza vaccine|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination of Nivolumab and Ipilimumab in Breast, Ovarian and Gastric Cancer Patients
Status: TERMINATED
Conditions: Breast Cancer Female|Ovarian Cancer|Gastric Cancer
Interventions: BIOLOGICAL: Nivolumab|BIOLOGICAL: Ipilimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Postoperative Pain After Endodontic Irrigation Using 1.3% Versus 5.25% Sodium Hypochlorite
Status: COMPLETED
Conditions: Dental Pulp Necrosis
Interventions: OTHER: 1.3% NaOCl|OTHER: 5.25% NaOCl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pharmacokinetics of Apixaban in Patients With Short Bowel Syndrome Requiring Long Term Parenteral Nutrition
Status: RECRUITING
Conditions: Short Bowel Syndrome|Anticoagulation
Interventions: DRUG: Apixaban single dose|DRUG: Apixaban steady-state
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact on Quality of Life in Patients Undergoing Total Gastrectomy or Proximal Gastrectomy for Adenocarcinoma of Esophagogastric Junction
Status: UNKNOWN
Conditions: Adenocarcinoma of Esophagogastric Junction.
Interventions: OTHER: Total Gastrectomy or Proximal Gastrectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: VenaTech Convertible Vena Cava Filter U.S. Multi-Center Clinical Trial
Status: COMPLETED
Conditions: Pulmonary Embolism
Interventions: DEVICE: VenaTech Convertible Vena Cava Filter|PROCEDURE: Vena Cava Filter Conversion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Pamphlet Supported Counseling During Child Immunization on the Initiation of Post-partum Family Planning
Status: UNKNOWN
Conditions: Family Planning
Interventions: BEHAVIORAL: pamphlet describing the timing of family planning during postpartum with methods advantages and disadvantages of family planning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Bioequivalence Study of Azithromycin Capsule and Reference Formulation Sumamed * in Healthy Adult Subjects in China
Status: COMPLETED
Conditions: Upper Respiratory Tract Infection|Lower Respiratory Infection|Skin Infection|Subcutaneous Tissues Infection|Genital Infection
Interventions: DRUG: test product (T) azithromycin capsule and reference product (R) azithromycin capsule "Sumamed®"
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Topical Antimicrobial Effectiveness Testing
Status: COMPLETED
Conditions: Antimicrobial Effectiveness
Interventions: DRUG: ChloraPrep One-Step|DRUG: 70% isopropyl alcohol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Multicenter Study to Assess Response to Influenza Vaccine in Multiple Sclerosis Participants Treated With Ofatumumab
Status: COMPLETED
Conditions: Relapsing Multiple Sclerosis
Interventions: BIOLOGICAL: Quadrivalent influenza vaccine|DRUG: Ofatumumab|DRUG: iDMT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasound-guided Approach Combined With Pressure Measurement Technique to Thoracic Paravertebral Block
Status: UNKNOWN
Conditions: Thoracotomy
Interventions: PROCEDURE: thoracic paravertebral block using pressure measurement technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Renal Effects of Two Iodinated Contrast Media in Patients at Risk Undergoing Computed Tomography
Status: TERMINATED
Conditions: Renal Insufficiency|Diabetes Mellitus
Interventions: DRUG: Iodixanol 320-Arm 1|DRUG: Iopamidol 300-Arm 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Effects of Acute Exercise Intensity on Cerebral Blood Flow and Cognitive Function in Older Adults
Status: COMPLETED
Conditions: Aging Well
Interventions: OTHER: Acute bout of Continuous Moderate Intensity Exercise|OTHER: Acute bout of High Intensity Interval Training|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Protocol for Optimizing Colonoscopy Preparation in Patients With Inflammatory Bowel Disease
Status: COMPLETED
Conditions: Inflammatory Bowel Diseases
Interventions: PROCEDURE: Endoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Antiretroviral Therapy (ART) Alone or With Delayed Chemo Versus ART With Immediate Chemo for Limited AIDS-related Kaposi's Sarcoma
Status: COMPLETED
Conditions: HIV-1 Infection|Kaposi's Sarcoma
Interventions: DRUG: efavirenz/emtricitabine/tenofovir disoproxil fumarate|DRUG: etoposide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Health Effects of Biostimulated Lettuce in Human
Status: COMPLETED
Conditions: Nutrition, Healthy|Dietary Deficiency|Bone Resorption|Glucose Metabolism Disorders|Lipid Metabolism Disorder|Hepatic Steatosis
Interventions: DIETARY_SUPPLEMENT: Control Group|DIETARY_SUPPLEMENT: Biostimulated group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Optimization of Smoking Cessation Strategies Concurrent With Treatment of Tobacco Related Malignancies
Status: COMPLETED
Conditions: Lung Cancer|Head and Neck Cancer
Interventions: DRUG: High Intensity Counseling + Long Acting NRT + PRN NRT|DRUG: High Intensity Counseling + bupropion + PRN NRT|DRUG: High Intensity Counseling + varenicline + PRN NRT|DRUG: High Intensity Counseling + Long Acting NRT|DRUG: High Intensity Counseling + bupropion|DRUG: High Intensity Counseling + varenicline|DRUG: Low Intensity Counseling + Long Acting NRT + PRN NRT|DRUG: Low Intensity Counseling + bupropion + PRN NRT|DRUG: Low Intensity Counseling + varenicline + PRN NRT|DRUG: Low Intensity Counseling + Long Acting NRT|DRUG: Low Intensity Counseling + bupropion|DRUG: Low Intensity Counseling + varenicline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EFFECTIVENESS OF VIRTUAL REALITY GLASSES VERSUS WHITE NOISE ON DENTAL ANXIETY IN CHILDREN WITH ATTENTION DEFICIT/ HYPERACTIVITY DISORDER
Status: COMPLETED
Conditions: Dental Anxiety
Interventions: DEVICE: Virtual Reality Glasses (VR)|OTHER: White noise|BEHAVIORAL: Basic behavior management techniques
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: An Expanded Access Study of Atezolizumab in Participants With Locally Advanced or Metastatic Urothelial Carcinoma After Failure With Platinum-Containing Chemotherapy
Status: APPROVED_FOR_MARKETING
Conditions: Urothelial Carcinoma
Interventions: DRUG: Atezolizumab [TECENTRIQ]
Study Type: EXPANDED_ACCESS
Clinical trial: Evaluating the Effect of Diabetes Control Through Intensive Lifestyle Modifications on Diabetic Peripheral Neuropathy
Status: COMPLETED
Conditions: Diabetic Polyneuropathy|Weight Loss
Interventions: OTHER: Weight Achievement and Intensive Treatment (Why WAIT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Cyclin Dependent Kinase (CDK)4/6 Inhibitor, PD0332991 in Advanced Non-small Cell Lung Cancer NSCLC.
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: PD0332991
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lipid-lowering Effect of Plant Stanol Yogurt
Status: COMPLETED
Conditions: Hypercholesterolemia|Hyperlipidemias|Dyslipidemias
Interventions: DIETARY_SUPPLEMENT: Yogurt that contains plant stanol esters|DIETARY_SUPPLEMENT: Placebo yogurt
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Innovative Therapeutic Approaches of Vaginal and Sexual Dysfunction After Breast Cancer Treatment
Status: RECRUITING
Conditions: Breast Cancer
Interventions: DEVICE: Hyaluronique Acid Gel|DEVICE: Laser CO2|DEVICE: Hyaluronique Acid Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1/2 Study of Epofolate (BMS-753493) in Subjects With Advanced Cancer (Schedule 2)
Status: TERMINATED
Conditions: Advanced Solid Tumors
Interventions: DRUG: Epofolate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Magnetic Resonance Guided Focal Stereotactic Body Radiation Therapy for Localized Prostate Cancer
Status: COMPLETED
Conditions: Adenocarcinoma of the Prostate|Recurrent Prostate Cancer|Stage I Prostate Cancer|Stage IIA Prostate Cancer|Stage IIB Prostate Cancer
Interventions: RADIATION: stereotactic radiosurgery|DEVICE: magnetic resonance imaging|OTHER: quality-of-life assessment|PROCEDURE: Serum Prostate Antigen Test|PROCEDURE: Digital Rectal Exam|BEHAVIORAL: Expanded Prostate Cancer Index Composite
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immuno Nutrition by L-citrulline for Critically Ill Patients
Status: COMPLETED
Conditions: Intubation|Pulmonary Ventilation
Interventions: PROCEDURE: Enteral nutrition|DIETARY_SUPPLEMENT: L-Citrulline|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Clobetasol for Oral Graft-Versus-Host Disease
Status: COMPLETED
Conditions: Oral Chronic Graft vs Host Disease
Interventions: DRUG: Clobetasol Oral Rinse|DRUG: Placebo oral rinse
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Reverse Transcriptase Inhibitors in Aicardi Goutières Syndrome
Status: NOT_YET_RECRUITING
Conditions: Aicardi Goutières Syndrome
Interventions: DRUG: Tenofovir (TDF) and Emtricitabine (FTC)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility and Efficacy Study of the CardioPulmonary Management (CPM) System in Patients With Chronic Heart Failure ( BETA )
Status: RECRUITING
Conditions: Heart Failure
Interventions: DEVICE: CardioPumlonary Management System (CPM)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Immunogenicity of CJCV2 With and Without ALFQ
Status: ACTIVE_NOT_RECRUITING
Conditions: Campylobacter Infection
Interventions: DRUG: ALFQ|BIOLOGICAL: CJCV2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Prognostic Biomarkers in Tumor Tissue Samples From Young Patients With Neuroblastoma
Status: COMPLETED
Conditions: Disseminated Neuroblastoma|Localized Resectable Neuroblastoma|Localized Unresectable Neuroblastoma|Recurrent Neuroblastoma|Stage 4S Neuroblastoma
Interventions: OTHER: diagnostic laboratory biomarker analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Supplementation With Ginseng and BCAA Improved Central Fatigue and Enhanced Attention During Exercise
Status: COMPLETED
Conditions: Exercise Addiction
Interventions: DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: Gojinsen® drinks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Torrent Pharmaceutical Limited's Pantoprazole Sodium 40 mg Delayed Release Tablets Under Fasting Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Torrent's Pantoprazole Sodium Delayed - Release Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose:
Clinical trial: High Altitude Residents With High Altitude Pulmonary Hypertension (HAPH), SDB Assessed at HA (3200 m) vs LA (760 m)
Status: NOT_YET_RECRUITING
Conditions: High Altitude Pulmonary Hypertension
Interventions: OTHER: SDB assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Impact on Patient COmpliance With Medication Using Pre-packaged Blisters for Long-term Medical therapY
Status: COMPLETED
Conditions: Medication Adherence|Medication Compliance
Interventions: BEHAVIORAL: Pre-packed blisters for distribution of medications|BEHAVIORAL: Routine distribution of medications
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effect of Intralesian Injection of Umbilical Cord Mesenchymal Stem Cells, Its Conditioned Medium, and Triamcinolone Acetonide on Type 1:3 Collagen Ratio and Interleukin-10 Levels in Keloid: A Randomised Controlled Trial
Status: COMPLETED
Conditions: Keloid|Stem Cell
Interventions: BIOLOGICAL: umbilical cord-derived mesenchymal stem cells (UC-MSC)|BIOLOGICAL: umbilical cord-derived mesenchymal stem cells conditioned medium (UC-CM)|DRUG: Triamcinolone Acetonide (TA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Improving Cardiovascular Health in Patients With Chronic Obstructive Pulmonary Disease
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Resveratrol|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Bovine Colostrum/ Egg Supplementation in Young Malawian Children
Status: COMPLETED
Conditions: Stunting|Environmental Enteric Dysfunction
Interventions: DIETARY_SUPPLEMENT: BC/ egg|DIETARY_SUPPLEMENT: Control|DIETARY_SUPPLEMENT: multiple micronutrient
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Kiwifruit on Gastrointestinal Fluid Distribution and Transit in Healthy Volunteers
Status: COMPLETED
Conditions: Constipation|Diet Modification
Interventions: DIAGNOSTIC_TEST: MRI Scan|OTHER: Kiwifruit|OTHER: calorie-matched sugar drink
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Safety of Buspirone, Sustained-release Tablets, 15 mg in Patients With Autonomic Dysfunction Syndrome Accompanied by Vertigo
Status: COMPLETED
Conditions: Vertigo|Autonomic Dysfunction
Interventions: DRUG: Buspirone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial of AAV2-BDNF Gene Therapy in Early Alzheimer's Disease and Mild Cognitive Impairment
Status: RECRUITING
Conditions: Alzheimer's Disease|Mild Cognitive Impairment
Interventions: GENETIC: AAV2-BDNF Gene Therapy|BIOLOGICAL: AAV2-BDNF Gene Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tisagenlecleucel In Primary CNS Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Primary CNS Lymphoma|Refractory Primary CNS Lymphoma|Relapsed Primary CNS Lymphoma
Interventions: BIOLOGICAL: Tisagenlecleucel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial of NNC0109-0012, an Anti-IL-20 Biologic, in Patients With Active Rheumatoid Arthritis Who Are Inadequate Responders to Anti-TNFa Biologics
Status: TERMINATED
Conditions: Inflammation|Rheumatoid Arthritis
Interventions: DRUG: NNC0109-0012|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Complete Removal of Neoplastic Large Colorectal Polyps: a Prospective Randomized Comparison of Endoscopic Mucosal Resection or Conventional Polypectomy
Status: COMPLETED
Conditions: Colorectal Polyps
Interventions: PROCEDURE: Endoscopic mucosal resection|PROCEDURE: Conventional polypectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Initiation of Noninvasive Ventilation in ALS Patients With Chronic Respiratory Insufficiency
Status: RECRUITING
Conditions: Ventilation Therapy|ALS|Chronic Respiratory Failure
Interventions: OTHER: NIV initiation in patients with ALS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study to Determine the Impact of Multiple Doses of Ketoconazole on Single-Dose Pharmacokinetics of HCV-796
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Ketoconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Growth Hormone on Uterine Receptivity in Women With RIF in an Oocyte Donation Program
Status: UNKNOWN
Conditions: Female Infertility
Interventions: BIOLOGICAL: Growth Hormone (GH)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Aesculus Hippocastanum L. on Fontan Circulation
Status: WITHDRAWN
Conditions: Univentricular Heart
Interventions: DRUG: Aesculus Hippocastanum / Horse Chestnut|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Virtual Reality Walking for Neuropathic Pain in Spinal Cord Injury
Status: COMPLETED
Conditions: Spinal Cord Injuries|Neuropathic Pain
Interventions: OTHER: Non-Interactive Virtual Reality Walking|OTHER: Interactive Virtual Reality Walking
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dose-Defining Safety and Immunogenicity Study of MTBVAC in South African Neonates
Status: COMPLETED
Conditions: Tuberculosis
Interventions: BIOLOGICAL: MTBVAC|BIOLOGICAL: BCG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Impact of Silymarin Dosages to Decrease Drug-induced Elevated Liver Enzymes Compared to Placebo
Status: UNKNOWN
Conditions: Drug-induced Liver Injury
Interventions: DRUG: Placebo|DRUG: 2x 140 mg per day|DRUG: 3x 280 mg per day|DRUG: 1x 1120 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Prospective, Randomized Study Comparing Cemented and Cementless Total Knee Replacement
Status: ACTIVE_NOT_RECRUITING
Conditions: Knee Osteoarthritis
Interventions: DEVICE: High-Flexion Knee Replacement System using Cemented Fixation|DEVICE: High-Flexion Knee Replacement System using Cementless Fixation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cyclosporine Plus Methotrexate or Alemtuzumab
Status: TERMINATED
Conditions: Unrecognized Condition: Mature B or T-cell Neoplasm
Interventions: DRUG: Cyclosporine + METHOTREXATE|DRUG: Cyclosporine + CAMPATH-1H
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aneuploidy Rates in Advanced Maternal Age Patients Supplemented With Coenzyme Q10 (CoQ10) Versus Those That Are Not: a Pilot Study
Status: COMPLETED
Conditions: Mitochondrial DNA|Aneuploidy
Interventions: DIETARY_SUPPLEMENT: CoQ10|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Percutaneous Radiofrequency Ablation of Parietal Endometriosis (PRFA)
Status: COMPLETED
Conditions: Endometriosis
Interventions: DEVICE: Percutaneous radiofrequency ablation of parietal endometriosis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Brief Stresses Experimental Study
Status: TERMINATED
Conditions: DNA Damage|Psychological Stress
Interventions: DRUG: Propranolol|DRUG: Placebo oral capsule|BEHAVIORAL: Acute stress task|BEHAVIORAL: No stress task
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effects of Adrenaline and Milrinone in Patients With Myocardial Dysfunction After CABG
Status: COMPLETED
Conditions: Cardiac Output, Low
Interventions: DRUG: adrenaline|DRUG: milrinone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: AB-101 as Monotherapy and With Immunotherapy in Patients With Relapsed/Refractory B-Cell Non-Hodgkin Lymphoma
Status: RECRUITING
Conditions: Non Hodgkin Lymphoma
Interventions: DRUG: AB-101|DRUG: Rituximab|DRUG: Interleukin-2|DRUG: Cyclophosphamide|DRUG: Fludarabine|DRUG: Bendamustine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluate Efficacy of Respiratory Rehabilitation Personalized Mobile Services for Respiratory Diseases
Status: COMPLETED
Conditions: Respiratory Disease|Lung Cancer|COPD
Interventions: OTHER: Fixed respiratory rehabilitation|OTHER: Responsive respiratory rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Evaluate ABT-494 (Upadacitinib) in Adults With Moderate to Severe Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: Upadacitinib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hospital Processes Reengineering of Intravenous Thrombolysis in Acute Ischemic Stroke in China
Status: COMPLETED
Conditions: Ischemic Stroke|Adverse Effect of Thrombolytic Drugs, Sequela
Interventions: BEHAVIORAL: Advance hospital notification by EMS|BEHAVIORAL: stroke team notification|BEHAVIORAL: key performance indicators feedback form|BEHAVIORAL: standard informed consent procedures|BEHAVIORAL: performance of thrombolysis at CT-room
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Demonstrate the Lot-to-lot Consistency of 3 Consecutive Batches and to Evaluate the Efficacy and Safety of GC FLU®Pre-filled Syringe Injection and 'GC FLU®Injection' Administration.
Status: COMPLETED
Conditions: Prevention of Influenza
Interventions: DRUG: GC FLU® Injection, GC FLU® Pre-filled Syringe Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy of High Dose atorvaSTATIN Loading Before Primary Percutaneous Coronary Intervention in ST Elevation Myocardial Infarction (STATIN STEMI)
Status: COMPLETED
Conditions: Myocardial Infarction|Angioplasty|Percutaneous Coronary
Interventions: DRUG: Atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Oxytocin on Face Perception
Status: SUSPENDED
Conditions: Healthy|Congenital Prosopagnosia
Interventions: DRUG: Oxytocin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Clinical Outcome of Triheptanoin Treatment in Patients With Long-chain Fatty Acid Oxidation Disorders (LC-FAOD) Treated Under Expanded Access Program
Status: COMPLETED
Conditions: Long-chain Fatty Acid Oxidation Disorders (LC-FAOD)
Interventions: OTHER: No Intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Expanded Access Protocol (EAP) Using the CliniMACS® Device for Pediatric Haplocompatible Donor Stem Cell Transplant
Status: NO_LONGER_AVAILABLE
Conditions: Acute Lymphoblastic Leukemia|Acute Myeloid Leukemia|Chronic Myeloid Leukemia|Myelodysplastic Syndrome|Lymphomas|Bone Marrow Failure|Hemoglobinopathy|Immune Deficiency|Osteopetrosis|Cytopenias|Leukocyte Disorders|Anemia Due to Intrinsic Red Cell Abnormality
Interventions: BIOLOGICAL: CD34+ enriched, T Cell Depleted donor stem cell product
Study Type: EXPANDED_ACCESS
Clinical trial: A Study of LCAR-B38M CAR-T Cells, a Chimeric Antigen Receptor T-cell (CAR-T) Therapy Directed Against B-cell Maturation Antigen (BCMA) in Chinese Participants With Relapsed or Refractory Multiple Myeloma
Status: RECRUITING
Conditions: Multiple Myeloma
Interventions: BIOLOGICAL: LCAR-B38M CAR-T Cell
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ESP Block vs FIB in Patients Undergoing Hip Arthroplasty
Status: UNKNOWN
Conditions: Hip Arthropathy
Interventions: PROCEDURE: Erector spinae plain block|PROCEDURE: Fascia Iliaca block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Efficacy and Safety of Amodiaquine and Amodiaquine-Artesunate
Status: UNKNOWN
Conditions: Malaria
Interventions: DRUG: amodiaquine-artesunate versus amodiaquine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Study of Carfilzomib and Vorinostat for Relapsed or Refractory Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: DRUG: Drug: Carfilzomib|DRUG: Vorinostat
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, PK/PD, and Immunogenicity Study of SC ALXN2030 in Healthy Participants
Status: RECRUITING
Conditions: Healthy
Interventions: DRUG: ALXN2030|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Electronic Alert System for Improving Thromboprophylaxis in Hospitalized Medical Patients
Status: COMPLETED
Conditions: Venous Thromboembolism
Interventions: OTHER: Electronic alert and the Geneva Risk Score calculation tool issued in the electronic patient chart
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A RCT Evaluating an Online Intervention in Increasing Pneumococcal Vaccination Among Older Adults
Status: RECRUITING
Conditions: Vaccination Refusal
Interventions: BEHAVIORAL: Chatbot-delivered interventions tailored to stage of changes|BEHAVIORAL: Chatbot-delivered standard interventions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Indomethacin Germinal Matrix Hemorrhage/Intraventricular Hemorrhage (GMH/IVH) Prevention Trial
Status: COMPLETED
Conditions: Intraventricular Hemorrhage (IVH)|Bleeding in the Brain|Prematurity|Very Low Birth Weight Infants
Interventions: DRUG: indomethacin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: EFfect of Ferric Carboxymaltose on exercIse CApacity and Cardiac Function in Patients With Iron deficiencY and Chronic Heart Failure
Status: TERMINATED
Conditions: Chronic Heart Failure|Iron Deficiency|Iron Deficiency Anemia|Anaemia
Interventions: DRUG: Ferinject ® (Ferric carboxymaltose)|DRUG: Normal saline (0.9%)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Vortioxetine Versus Escitalopram on Cognitive Function in Patients With Inadequate Response to Current Antidepressant Treatment of Major Depressive Disorder
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: Vortioxetine 10-20 mg|DRUG: Escitalopram 10-20 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Short-term Stenting Versus Balloon Dilatation for Dominant Strictures in Primary Sclerosing Cholangitis
Status: UNKNOWN
Conditions: Primary Sclerosing Cholangitis
Interventions: PROCEDURE: plastic endoprosthesis|PROCEDURE: balloon dilatation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Behavioral Intervention For BMT/SCT Survivors
Status: COMPLETED
Conditions: Hodgkin's Disease|Leukemia|Multiple Myeloma|Non-Hodgkin's Lymphoma
Interventions: BEHAVIORAL: Cognitive Behavioral Therapy: Questionnaires|BEHAVIORAL: Usual Care: Questionnaires
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Promoting Well-being and Health in Heart Failure
Status: RECRUITING
Conditions: Heart Failure|Heart Failure NYHA Class I|Heart Failure NYHA Class II|Heart Failure NYHA Class III
Interventions: BEHAVIORAL: PP-MI Intervention|BEHAVIORAL: MI-alone Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Lopinavir/Ritonavir Tablets Comparing Once-Daily Versus Twice-Daily Administration When Coadministered With Nucleoside/Nucleotide Reverse Transcriptase Inhibitors in Antiretroviral-Experienced Human Immunodeficiency Virus Type 1 Infected Subjects
Status: COMPLETED
Conditions: Human Immunodeficiency Virus Infections
Interventions: DRUG: lopinavir/ritonavir (LPV/r) tablet with nucleoside/nucleotide reverse transcriptase inhibitors (NRTIs)|DRUG: lopinavir/ritonavir (LPV/r) tablet with nucleoside/nucleotide reverse transcriptase inhibitors (NRTIs)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Evaluation of Strategic Intervention in Multidrug Resistant Patients With Tipranavir (RESIST)
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Tipranavir|DRUG: Ritonavir(r)|DRUG: Comparator Protease Inhibitor (CPI)
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Total Glucosides of Paeony Combined With NB-UVB on Treating Vitiligo
Status: COMPLETED
Conditions: Vitiligo
Interventions: DRUG: Total Glucosides of Paeony(TGP)|DEVICE: Narrow band-ultraviolet b（NB-UVB）|DRUG: Total Glucosides of Paeony(TGP) analogue
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prevention of Leg Cramps Using Compression Stockings or Magnesium Supplements in the Age Group of 50 to 84
Status: UNKNOWN
Conditions: Muscle Cramp|Stockings, Compression|Magnesium
Interventions: OTHER: Compression stocking|DIETARY_SUPPLEMENT: Magnesium tablet|OTHER: Placebo tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Liposomal Bupivacaine for Pain Control Following Anterior Cruciate Ligament Reconstruction
Status: COMPLETED
Conditions: Anterior Cruciate Ligament Rupture
Interventions: DRUG: Exparel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Obinutuzumab in Combination With Ibrutinib in Treating Patients With Relapsed Mantle Cell Lymphoma
Status: COMPLETED
Conditions: Recurrent Mantle Cell Lymphoma|Refractory Mantle Cell Lymphoma
Interventions: DRUG: Ibrutinib|BIOLOGICAL: Obinutuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Precision-Panc Master Protocol: Personalising Treatment for Pancreatic Cancer
Status: RECRUITING
Conditions: Neoplasms Pancreatic
Interventions: OTHER: Patients with suspected or confirmed pancreatic cancer will be be asked to provide biopsy material for molecular profiling
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: CARbon monoxidE intoxiCatiOn in Korea: Prospective Cohort (CARE CO Cohort)
Status: RECRUITING
Conditions: Carbon Monoxide Poisoning|Myocardial Injury|Neurologic Deficits|Image, Body|Therapy|Prognostic Factors|Complications
Interventions: DIAGNOSTIC_TEST: Cardiac MRI|PROCEDURE: Hyperbaric oxygen therapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Dose-Ranging Study of the Safety and Effectiveness of MK-8237 in the Treatment of House Dust Mite (HDM) Induced Allergic Rhinitis/Rhinoconjunctivitis in Adults (MK-8237-003/P07627)
Status: COMPLETED
Conditions: Rhinitis, Allergic, Perennial|Rhinitis, Allergic, Nonseasonal
Interventions: DRUG: Placebo|DRUG: MK-8237 6 DU|DRUG: MK-8237 12 DU
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Autogenous Demineralized Dentin Block Graft Versus Autogenous Bone Block Graft for Alveolar Ridge Preservation
Status: UNKNOWN
Conditions: Alveolar Bone Loss
Interventions: PROCEDURE: Alveolar ridge preservation using autogenous demineralized dentin block graft|PROCEDURE: Alveolar ridge preservation using autogenous bone block graft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Maxillary Canine Retraction Assisted With Two Different Methods of Low-Intensity Pulsed Ultrasound
Status: RECRUITING
Conditions: Orthodontic Appliance Complication
Interventions: DEVICE: Low-Intensity Pulsed Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare Two Different Managements After Ankle Surgery: Immediate and Delayed Weight-bearing.
Status: RECRUITING
Conditions: Lateral Malleolus Fracture
Interventions: OTHER: immediate post-operative complete weight-bearing after surgery|OTHER: delayed weight-bearing for 6 weeks after surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of mRNA Vaccine in Patients With Liver Cancer After Operation
Status: NOT_YET_RECRUITING
Conditions: Posto Perative Hepatocellular Carcinoma
Interventions: DRUG: Neoantigen mRNA Personalised Cancer vaccine in combination with Stintilimab I njection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Immune Response of Candidate H1N1 Influenza Vaccine GSK2340274A Following Seasonal Influenza Vaccination in Adults
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: GSK Biologicals' FluLaval®|BIOLOGICAL: Placebo (saline)|BIOLOGICAL: GSK Biologicals' investigational H1N1 Influenza Vaccine - GSK2340274A|BIOLOGICAL: GSK Biologicals' investigational H1N1 Influenza Vaccine - GSK2340273A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy of Oshadi D and Oshadi R in Basal Cell Carcinoma Patients Prior to Tumor Excision a Phase 2 Study
Status: COMPLETED
Conditions: BCC
Interventions: DRUG: Oshadi D & Oshadi R
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Decompression in Patient With Acute vs Chronic Lumbar Radiculopathy
Status: COMPLETED
Conditions: Lumbar Radiculopathy
Interventions: OTHER: Decompression + Hot pack, TENS, Mobilization, Exercise Therapy|OTHER: Decompression + Hot pack , TENS , Mobilization , Exercise Therapy|OTHER: Hot pack , TENS, Mobilization, Exercise therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testing How the Body Responds to the Drug CBX-12 in Patients With Advanced Solid Cancers
Status: RECRUITING
Conditions: Advanced Malignant Solid Neoplasm|Metastatic Malignant Solid Neoplasm
Interventions: PROCEDURE: Biopsy|PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|DRUG: pH Low Insertion Peptide-exatecan Conjugate CBX-12
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Malaria: Relative Bioavailability and Food Effect of DSM265
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: DSM265-TPGS 34% SDD, 400 mg fasted|DRUG: DSM265-TPGS 34% SDD, 400 mg fed|DRUG: DSM265 25% SDD, 400 mg fasted
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Pulmonary Hypertension: Intensification and Personalisation of Combination Rx
Status: RECRUITING
Conditions: Pulmonary Arterial Hypertension
Interventions: DRUG: Selexipag|DRUG: Riociguat|DEVICE: CardioMEMS pulmonary artery pressure monitor|DEVICE: Confirm Rx
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Genetic Study of Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS)
Status: RECRUITING
Conditions: Chronic Prostatitis (CP)|Chronic Pelvic Pain Syndrome (CPPS)|Painful Bladder Syndrome (PBS)|Benign Frequency Syndrome (BFS)|Interstitial Cystitis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Valuate the Clinical Performance and Safety of da Vinci SP Surgical System
Status: RECRUITING
Conditions: da Vinci SP Surgical System|Thoracic Surgery
Interventions: DEVICE: da Vinci SP Surgical System for Single-Port Thoracic Surgeries
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pharmacokinetic Study to Characterize JNJ-39393406 in the Cerebrospinal Fluid of Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: JNJ-39393406|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: A Controlled Study With Remote Web-based Adapted Physical Activity (e-APA) in Psychotic Disorders
Status: TERMINATED
Conditions: Schizophrenia|Physical Activity|Schizo Affective Disorder
Interventions: BEHAVIORAL: Physical activity (APA)|BEHAVIORAL: Health Education program (HE)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Permissive Hypercapnia During One Lung Ventilation: Impact on Right Ventricular Systolic and Diastolic Functions During Lung Resection
Status: COMPLETED
Conditions: Anesthesia
Interventions: PROCEDURE: Permissive hypercapnia
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: RCT: the Effectiveness of LifeHack in Improving Mental Wellbeing in University Students.
Status: RECRUITING
Conditions: Internet-based Intervention|Waiting List Control Group|Depression|Anxiety|Stress|Quality of Life|Mental Wellbeing|Resilience
Interventions: BEHAVIORAL: LifeHack
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Transfemoral Transcatheter Aortic Valve Implementation at Hospital Without On-site Cardiac Surgery: Early Clinical Outcome in Patients With Prohibitive Surgical Risk.
Status: RECRUITING
Conditions: Aortic Stenosis
Interventions: DEVICE: Transfemoral transcatheter aortic valve implementation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Sitagliptin on Type 2 Diabetes Mellitus Patients on Treatment With Metformin and Insulin
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Sitagliptin|DRUG: Glimepiride|DRUG: Metformin|DRUG: Insulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Polymorphisms of OAT1, OAT3, and OCT2 on Transportation of Potential Nephrotoxic Drugs
Status: COMPLETED
Conditions: Adverse Effects
Interventions: PROCEDURE: Vancomycin|PROCEDURE: DNA are extracted from the whole blood of subjects
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION