pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Evaluation of 2 Interferon γ Assays in the Diagnosis of Latent Tuberculosis in HIV-infected Patients.ANRS EP 40 QUANTI SPOT
Status: COMPLETED
Conditions: HIV Infections|Tuberculosis
Interventions: DEVICE: QuantiFERON TB Gold In-Tube|DEVICE: T-SPOT.TB®
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Fecal Microbiota Transplantation for Steroid Resistant/Dependent Acute GI GVHD
Status: COMPLETED
Conditions: Hematopoietic and Lymphoid Cell Neoplasm
Interventions: BIOLOGICAL: fecal microbiome transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prophylactic Effects of Ondansetron, Ramosetron, and Palonosetron on Patient-Controlled Analgesia Related Nausea and Vomiting After Urologic Laparoscopic Surgery
Status: COMPLETED
Conditions: Laparoscopic Marsupialization of Renal Cyst
Interventions: DRUG: Ondansetron|DRUG: Ramosetron|DRUG: Palonosetron|DRUG: Normal saline inj
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Tu Salud (Your Health) Randomized Control Study in Patients With Diabetes Using a Mobile App.
Status: UNKNOWN
Conditions: Diabetes Mellitus
Interventions: OTHER: OneTouch Reveal® Mobile APP system|OTHER: Current Blood Glucose Monitor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Search for Diagnostic and Prognostic Biomarkers in Systemic Sclerosis and Inflammatory Myopathies
Status: RECRUITING
Conditions: Systemic Sclerosis|Inflammatory Myopathies
Interventions: OTHER: Collection of biological samples
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Initial Triple Therapy Including Parenteral Treprostinil vs Initial Double Oral Therapy in PAH Group I Patients
Status: RECRUITING
Conditions: Pulmonary Arterial Hypertension
Interventions: DRUG: Generic treprostinil sodium + Standard of Care (Double Oral)|DRUG: Standard of Care - Double Oral
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Maximal Use Study of Tapinarof Cream, 1% in Pediatric Subjects With Extensive Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: Tapinarof cream, 1%
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Use of Oral Appliances as an Adjunct to Continuous Positive Airway Pressure (CPAP) in the Treatment of Obstructive Sleep Apnoea
Status: COMPLETED
Conditions: Obstructive Sleep Apnoea
Interventions: DEVICE: The Klearway™ oral appliance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Phase 1 Study of ELX-02 in Healthy Adult Subjects
Status: COMPLETED
Conditions: Genetic Disease|Nonsense Mutation
Interventions: DRUG: ELX-02|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Allopurinol as a Possible Oxygen Sparing Agent During Exercise in Peripheral Arterial Disease
Status: COMPLETED
Conditions: Peripheral Arterial Disease
Interventions: DRUG: Allopurinol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Matching Perfusion and Metabolic Activity in HFpEF
Status: RECRUITING
Conditions: Heart Failure With Preserved Ejection Fraction
Interventions: DRUG: Potassium Nitrate|DRUG: Potassium Nitrate + Propionyl-L-Carnitine + Nicotinamide Riboside|OTHER: Potassium Chloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Quetiapine Fumarate Sustained Release (SEROQUEL SR) in Combination With an Antidepressant in the Treatment of Major Depressive Disorders
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: Quetiapine fumarate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Study of the Tolerability and Pharmacokinetic of ZL-2102 With an Investigation of Food Effect in Healthy Male Subjects
Status: UNKNOWN
Conditions: Chronic Obstructive Pulmonary Disease|Asthma|Idiopathic Pulmonary Fibrosis
Interventions: DRUG: ZL-2102|DRUG: Placebo matching ZL-2102
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Immunogenicity of the AIDSVAX B/E Vaccine and the MVA/HIV62B Vaccine in Healthy, HIV-1-Uninfected Adults Who Previously Received MVA/HIV62B in DNA/MVA or MVA/MVA Regimens in HVTN 205
Status: COMPLETED
Conditions: HIV Infections
Interventions: BIOLOGICAL: MVA/HIV62B vaccine|BIOLOGICAL: AIDSVAX B/E vaccine|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Complementary Intradialytic Nutritional Supplementation in Dialysis Patients
Status: TERMINATED
Conditions: End Stage Renal Disease
Interventions: DRUG: Nepro nutritional supplement|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study VEPEMB In Patients With Hodgkin's Lymphoma Aged ≥ 60 Years
Status: COMPLETED
Conditions: Lymphoma
Interventions: BIOLOGICAL: bleomycin sulfate|DRUG: cyclophosphamide|DRUG: etoposide|DRUG: mitoxantrone hydrochloride|DRUG: prednisolone|DRUG: procarbazine hydrochloride|DRUG: vinblastine sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TRAnexamic Acid for Preventing Postpartum Hemorrhage Following a Cesarean Delivery
Status: COMPLETED
Conditions: Postpartum Hemorrhage
Interventions: DRUG: Tranexamic Acid Injectable Solution|DRUG: Sodium Chloride 0.9%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Use of Artificial Intelligence-Guided Echocardiography to assIst cardiovascuLar Patient managEment
Status: RECRUITING
Conditions: Heart Failure|Valve Heart Disease
Interventions: DIAGNOSTIC_TEST: AI-guided echo|DIAGNOSTIC_TEST: Standard echo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: The Efficacy of Kinesio Taping With Therapy in the Treatment of Globus Pharyngeus
Status: UNKNOWN
Conditions: Globus Pharyngeus
Interventions: DEVICE: Kinesio tape
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Fusion Versus The Affinity Oxygenation Systems
Status: UNKNOWN
Conditions: Complication of Coronary Artery Bypass Graft
Interventions: DEVICE: fusion oxygenation system|DEVICE: Affinity oxygenation system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Pecto-intercostal Plane Block in On-pump Coronary Bypass Graft Surgery
Status: COMPLETED
Conditions: Enhanced Recovery After Cardiac Surgery
Interventions: PROCEDURE: pecto-intercostal plane block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Effectiveness of Juvéderm® Volbella With Lidocaine Versus Restylane-L® for Lip Volume Enhancement
Status: COMPLETED
Conditions: Lip Volume Enhancement
Interventions: DEVICE: Juvéderm® Volbella with Lidocaine|DEVICE: Restylane-L®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Asthma Symptom Based Adjustment of Inhaled Steroid Therapy in African American Children
Status: COMPLETED
Conditions: Asthma
Interventions: OTHER: Asthma controller medication (Beclomethasone) adjustment strategy|OTHER: Provider-based adjustment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility of Parasacral Transcutaneous Electrical Nerve Stimulation PTENS for Voiding Dysfunction in Peds Population
Status: COMPLETED
Conditions: Overactive Bladder|Voiding Disorders|Incontinence, Urinary
Interventions: DEVICE: parasacral transcutaneous electrical nerve stimulation (PTENS)|OTHER: Standard Urotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Fish Oil Supplementation on Cognition in MCI Patients and the Influence of the APOE4 Allele
Status: COMPLETED
Conditions: Mild Cognitive Impairment
Interventions: DIETARY_SUPPLEMENT: fish oil|DIETARY_SUPPLEMENT: placebo, sunflower oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Dominantly Inherited Alzheimer Network Trial: An Opportunity to Prevent Dementia. A Study of Potential Disease Modifying Treatments in Individuals at Risk for or With a Type of Early Onset Alzheimer's Disease Caused by a Genetic Mutation. Master Protocol DIAN-TU-001
Status: RECRUITING
Conditions: Alzheimers Disease|Dementia|Alzheimers Disease, Familial
Interventions: DRUG: Gantenerumab|DRUG: Solanezumab|DRUG: Matching Placebo (Gantenerumab)|DRUG: Matching Placebo (Solanezumab)|DRUG: Gantenerumab|DRUG: E2814|DRUG: Lecanemab|DRUG: Matching Placebo (E2814)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: HELP-Apheresis in Diabetic Ischemic Foot Treatment (H.A.D.I.F)
Status: COMPLETED
Conditions: Foot Ulcers|Arteriosclerosis Obliterans|Diabetes Mellitus
Interventions: DEVICE: LDL-apheresis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dextromethorphan Added on for Children With Chronic Irritability
Status: ENROLLING_BY_INVITATION
Conditions: Irritable Mood
Interventions: DRUG: Dextromethorphan|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Curcumin and Intravitreal Dexamethasone in Diabetic Macular Edema
Status: COMPLETED
Conditions: Diabetic Macular Edema
Interventions: COMBINATION_PRODUCT: DIABEC plus intravitreal dexamethazone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of Lipiflow®-Treatment and a Standard Lid Hygiene Regime
Status: COMPLETED
Conditions: Meibomian Gland Dysfunction
Interventions: DEVICE: Lipiflow|BEHAVIORAL: Lid hygiene regime
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Low Dose Aspirin for the Prevention of Preeclampsia
Status: UNKNOWN
Conditions: Preeclampsia
Interventions: DRUG: Aspirin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Immune Responses in Healthy Adults Receiving Live Influenza Virus Vaccines
Status: COMPLETED
Conditions: Influenza, Human
Interventions: BIOLOGICAL: A/swine/Missouri/4296424/2006 (H2N3) x A/Ann Arbor/6/60 ca (H2N3 MO 2006/AA ca)|BIOLOGICAL: A/chicken/Hong Kong/G9/97 (H9N2) x A/Ann Arbor/6/60 ca (H9N2 G9/AA ca)|BIOLOGICAL: 2012-2013 trivalent seasonal live attenuated influenza vaccine (FluMist®)|BIOLOGICAL: Vaccine placebo (Leibovitz-15 [L-15])|BIOLOGICAL: Vaccine placebo (FluMist®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Anti-OX40, Cyclophosphamide (CTX) and Radiation in Patients With Progressive Metastatic Prostate Cancer
Status: COMPLETED
Conditions: Metastatic Prostate Cancer|Cancer of the Prostate|Prostate Cancer
Interventions: DRUG: Anti-OX40|RADIATION: Radiation|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phospholipid Hypothesis of Depression: From Molecular Biology, Neuroimaging to Behaviour
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DIETARY_SUPPLEMENT: EPA|DIETARY_SUPPLEMENT: DHA|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Prospective Study of Treating Duodenal Papillary Sphincter in Different Ways During ERCP
Status: UNKNOWN
Conditions: ERCP
Interventions: DEVICE: Erbao electric knife|DEVICE: Three-cavity incision knife|DEVICE: Columnar expansion balloon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Impact of Glossopharyngeal Nerve Block on Swallowing Difficulties Caused by Gastroesophageal Reflux Disease
Status: NOT_YET_RECRUITING
Conditions: Dysphagia
Interventions: BEHAVIORAL: Rehabilitation therapy|PROCEDURE: Glossopharyngeal Nerve Block|DRUG: Lidocaine Hydrochloride|BEHAVIORAL: placebo injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Methylene Blue Mouthwash for the Treatment of Oral Mucositis Pain in Patients with Cancer
Status: RECRUITING
Conditions: Hematopoietic and Lymphoid System Neoplasm|Malignant Solid Neoplasm|Stomatitis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Postcardiotomy Venoarterial Extracorporeal Membrane Oxygenation
Status: UNKNOWN
Conditions: Acute Heart Failure|Low Output Heart Failure|Cardiac Output, Low|Extracorporeal Membrane Oxygenation|Cardiac Surgery|Venoarterial Extracorporeal Membrane Oxygenation
Interventions: DEVICE: Venoarterial extracorporeal oxygenation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effects of EndoActivator on Postoperative Pain and Root Canal Treatment Success
Status: COMPLETED
Conditions: Periapical Periodontitis|Root Canal Infection
Interventions: PROCEDURE: Sonic Activation with EndoActivator|PROCEDURE: Control Needle Irrigation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Self-Management Intervention for Mild to Moderate Heart Failure
Status: COMPLETED
Conditions: Cardiovascular Diseases|Heart Diseases|Heart Failure, Congestive
Interventions: BEHAVIORAL: Self-Management|OTHER: attention control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: FEA, Biomechanical and Clinical Study of R.O. Peritrochanteric Fractures With PFLP vs Cephalomedullary Nail.
Status: RECRUITING
Conditions: Pertrochanteric Fracture of Femur, Closed
Interventions: DEVICE: Osteosynthesis cephalomedullary nail|DEVICE: Osteosynthesis proximal femur locking plate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Autologous CD34+ Stem Cell Injection for Severe Intermittent Claudication (Leg Pain)
Status: UNKNOWN
Conditions: Peripheral Artery Disease|Severe Intermittent Claudication
Interventions: BIOLOGICAL: Autologous Stem Cells (CD34+)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Collect and Evaluate the Safety and Efficacy Information of Korean Multiple Myeloma Patients Treated With REVLIMID®, After Approval of Marketing Authorization for New Drug in Korea
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: REVLIMID®|DRUG: Dexamethasone
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Dental-Child Interaction Training
Status: NOT_YET_RECRUITING
Conditions: Behavior and Behavior Mechanisms|Child Behavior
Interventions: BEHAVIORAL: Immediate intervention Group|BEHAVIORAL: Delayed intervention (control) Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Clinical Study on the Efficacy and Safety of c-Met/PD-L1 CAR-T Cell Injection in the Treatment of HCC
Status: UNKNOWN
Conditions: Primary Hepatocellular Carcinoma
Interventions: BIOLOGICAL: c-Met/PD-L1 CAR-T cell injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sitagliptin Cardiovascular Outcomes Study (MK-0431-082)
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Sitagliptin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Early Detection of Atrial Fibrillation Using Mobile Technology in Cryptogenic Stroke Patients
Status: RECRUITING
Conditions: Cryptogenic Stroke|Atrial Fibrillation
Interventions: DEVICE: seven-day ECG Holter|DEVICE: 24-hour blood pressure monitor|OTHER: Questionnaire: vision of mHealth|OTHER: Questionnaire: user experience & feeling of safety|DEVICE: Insertable loop recorder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: DIAGNOSTIC
Clinical trial: Mini Lateral Shoulder Approach
Status: COMPLETED
Conditions: Shoulder Impingement Syndrome|Rotator Cuff Tendinopathy|Adhesive Capsulitis and Frozen Shoulder Syndrome
Interventions: PROCEDURE: Mini Lateral Shoulder Approach (MLSA)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Effectiveness Study of The Swedish Adjustable Gastric Band (SAGB) in the Treatment of Morbid Obesity
Status: COMPLETED
Conditions: Obesity, Morbid
Interventions: DEVICE: Swedish Adjustable Gastric Band
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: rTMS as a Treatment of Visceral Pain Secondary to Malignancy
Status: COMPLETED
Conditions: Malignancy
Interventions: PROCEDURE: Real rTMS(20 Hz, 10 trains, inter train interval 30 sc with total pulses 2000, intensity 80% of motor threshold) daily for 10 consecutive days (5 days/week)|PROCEDURE: Sham rTMS (same parameters but with coil elevated and angled away from the head) every day for 10 consecutive days (5 days/week).
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Tegavivint (BC2059) in Patients With Advanced Hepatocellular Carcinoma
Status: RECRUITING
Conditions: Advanced Hepatocellular Carcinoma
Interventions: DRUG: Tegavivint|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of NV1FGF in Patients With Severe Peripheral Artery Occlusive Disease.
Status: COMPLETED
Conditions: Severe Peripheral Artery Occlusive Disease
Interventions: DRUG: XRP0038 (NV1FGF)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Data Analysis for Drug Repurposing for Effective Alzheimer's Medicines (DREAM) - Methotrexate vs Hydroxychloroquine
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Methotrexate|DRUG: Hydroxychloroquine
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Evaluate the Efficacy and Safety of Mitapivat in Pediatric Participants With Pyruvate Kinase Deficiency (PKD) Who Are Not Regularly Transfused, Followed by a 5-Year Extension Period
Status: ACTIVE_NOT_RECRUITING
Conditions: Pediatric Pyruvate Kinase Deficiency|Pediatric Hemolytic Anemia
Interventions: DRUG: Mitapivat|DRUG: Mitapivat-matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of a Novel Conjugate Vaccine Against Salmonella Typhi and Salmonella Paratyphi A in Healthy Adults
Status: RECRUITING
Conditions: Typhoid Fever
Interventions: BIOLOGICAL: TYP04A Low Dose without adjuvant investigational vaccine|BIOLOGICAL: TYP04B Full Dose without adjuvant investigational vaccine|BIOLOGICAL: TYP03A Low Dose adjuvanted investigational vaccine|BIOLOGICAL: TYP03B Full Dose adjuvanted investigational vaccine|BIOLOGICAL: Sanofi Pasteur's Typhoid Vi polysaccharide vaccine|BIOLOGICAL: GSK's Tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of BB-031 in Acute Ischemic Stroke Patients (RAISE)
Status: RECRUITING
Conditions: Acute Ischemic Stroke
Interventions: DRUG: BB-031|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of the Telitacicept in Pediatric Patients With Frequently Relapsing or Steroid Dependent Nephrotic Syndrome
Status: RECRUITING
Conditions: Nephrotic Syndrome in Children|Telitacicept
Interventions: DRUG: Telitacicept
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: L-DEP Regimen Combined With PD-1 Antibody as Induction Therapy for Epstein-Barr Virus-positive LA-HLH
Status: NOT_YET_RECRUITING
Conditions: PD-1 Antibody|Hemophagocytic Lymphohistiocytosis|Epstein-Barr Virus|Lymphoma
Interventions: DRUG: L-DEP and PD-1 antibody
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Safety and Efficacy of Glimepiride, Gliclazide, Repaglinide or Acarbose When Added to Sitagliptin + Metformin Combination Therapy in Chinese Participants With Diabetes (MK-0431-313)
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Metformin|DRUG: Sitagliptin|DRUG: Acarbose|DRUG: Repaglinide|DRUG: Glimepiride|DRUG: Gliclazide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Coagulation in Cirrhosis
Status: RECRUITING
Conditions: Liver Cirrhosis
Interventions: DRUG: Platelet Concentrate|DRUG: Prothrombin Complex Concentrate|OTHER: Restricitve Use
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, Pharmacokinetics of Intravenous FL058 and Meropenem in Healthy Subjects(SAD/MAD)
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: FL058 500mg and Meropenem 1000mg（ IV 120min）|DRUG: FL058 Placebo and Meropenem 1000mg（ IV 120min）|DRUG: FL058 1000mg（ IV 120min）|DRUG: FL058 Placebo （ IV 120min）|DRUG: Meropenem 1000 mg （ IV 120min）|DRUG: Meropenem Placebo （ IV 120min）|DRUG: FL058 1000mg and Meropenem 1000mg （ IV 120min）|DRUG: FL058 Placebo and Meropenem 1000mg （ IV 120min）|DRUG: FL058 1000mg and Meropenem 2000mg （ IV 120min）|DRUG: FL058 Placebo and Meropenem 2000m（ IV 120min）|DRUG: FL058 1000mg and Meropenem 2000mg （ IV 180min）|DRUG: FL058 Placebo and Meropenem 2000m（ IV 180min）|DRUG: FL058 2000mg and Meropenem 2000mg（ IV 180min）|DRUG: FL058 Placebo and Meropenem 2000mg（ IV 180min）
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bevacizumab as Adjunctive Treatment to Laser Panretinal Photocoagulation for Proliferative Diabetic Retinopathy
Status: UNKNOWN
Conditions: Proliferative Diabetic Retinopathy
Interventions: PROCEDURE: Panretinal photocoagulation|PROCEDURE: Procedure: Panretinal Photocoagulation (PRP) Drug: Intravitreous injection of Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Effects of HIgh Volume COntinuous REnal Replacement Therapy in Patients With Septic Acute Kidney Injury
Status: COMPLETED
Conditions: Sepsis|Kidney Failure, Acute|Renal Replacement Therapy
Interventions: DRUG: high dose CRRT|DRUG: Conventional dose CRRT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PeriImplant Soft Tissue and Marginal Bone Loss of Single Implant Mandibular Overdenture
Status: UNKNOWN
Conditions: Complete Edentulism
Interventions: DEVICE: ball attachment|DEVICE: cm loc attachment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tomodensitometric Study of Pulmonary Effects of Intrapulmonary Percussive Ventilation in ARDS Patients
Status: UNKNOWN
Conditions: ARDS
Interventions: DEVICE: VDR4 ventilator (Intrapulmonary Percussive Ventilation)|DEVICE: CT scan|DEVICE: Servo-i|DEVICE: - Intubation|DEVICE: Ventilation ( with an ICU conventional ventilator)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Humidification in Laparoscopic Colonic Surgery
Status: COMPLETED
Conditions: Peritoneal Inflammation
Interventions: PROCEDURE: Fisher and Paykel Humidifier (MR860)|PROCEDURE: Standard insufflation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of HIT in Patients With Non-alcoholic Fatty Liver Disease/Steatohepatitis
Status: COMPLETED
Conditions: Non-alcoholic Steatohepatitis|Non-alcoholic Fatty Liver Disease
Interventions: OTHER: High-intensity Interval Training
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevalence and Etiologies of Intracranial Stenosis in Patients With Antiphospholipid Syndrome
Status: ENROLLING_BY_INVITATION
Conditions: Antiphospholipid Syndrome|Stenosis|Intracranial Stenosis
Interventions: DIAGNOSTIC_TEST: Imaging assessment|DIAGNOSTIC_TEST: Neurosonology assessment|DIAGNOSTIC_TEST: Blood Test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phase I Study of D-0120 to Evaluate Safety and PK/PD Study in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: D-0120|DRUG: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Safety and Efficacy of Neuromultivit in Treatment of Vertebrogenic Radiculopathy
Status: COMPLETED
Conditions: Vertebrogenic Radiculopathy L5, S1
Interventions: DRUG: Neuromultivit|DRUG: Voltaren|DRUG: Sirdalud
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Semaglutide Improves Metabolic Abnormalities and Fertility in Obese Infertile Women With Polycystic Ovary Syndrome
Status: RECRUITING
Conditions: PCOS (Polycystic Ovary Syndrome)|Semaglutide
Interventions: DRUG: Metformin Hydrochloride 500 MG|DRUG: Semaglutide, 1.34 mg/mL|DRUG: Semaglutide, 1.34 mg/mL and Metformin Hydrochloride 500 MG|BEHAVIORAL: calorie-restricted diet|BEHAVIORAL: physical exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intranasal Midazolam in Children as a Pre-Operative Sedative - Part 2
Status: COMPLETED
Conditions: Sedation
Interventions: DRUG: Midazolam|DRUG: xylocaine|DRUG: saline placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Integrated Treatment Protocol for Acute Malnutrition: A Non Inferiority Trial in Burkina Faso
Status: COMPLETED
Conditions: Global Acute Malnutrition (GAM)
Interventions: DRUG: Ready to Use Therapeutic Food (RUTF)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dysphagia and Cervical Spine Disorders in Patients With Brain Lesions
Status: COMPLETED
Conditions: Prevention|Rehabilitation
Interventions: PROCEDURE: Videofluroscopic swallow study (VFSS)|PROCEDURE: cervical spine isometric exercises|PROCEDURE: Fiberoptic endoscopic esophageal study (FEES)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: ASSESS Study: Evaluation of ABSOLUTE™ Stent System for Occluded Arteries
Status: COMPLETED
Conditions: Peripheral Vascular Diseases
Interventions: DEVICE: ABSOLUTE™: Self-Expandable Peripheral Nitinol Stent
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of the Vitreomacular Interface on the Progression of the Diabetic Macular Edema After Anti-VEGF Injection
Status: COMPLETED
Conditions: Diabetic Macular Edema|Vitreomacular Interface|Anti-VEGF Treatment
Interventions: DRUG: Intravitreal Ranibizumab injection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Bortezomib, Dexamethasone, and Cyclophosphamide in Treating Older Patients With Multiple Myeloma
Status: WITHDRAWN
Conditions: Stage I Multiple Myeloma|Stage II Multiple Myeloma|Stage III Multiple Myeloma
Interventions: DRUG: bortezomib|DRUG: cyclophosphamide|DRUG: dexamethasone|OTHER: laboratory biomarker analysis|OTHER: quality-of-life assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Impact of Focused Ultrasound Thalamotomy of the Anterior Nucleus for Focal-Onset Epilepsy on Anxiety
Status: RECRUITING
Conditions: Anxiety|Medication-refractory Focal-onset Epilepsy
Interventions: DEVICE: Magnetic Resonance Imaging-guided Focused Ultrasound Ablation (MRgFUSA)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Influence of Brief Supportive Psychotherapy on Major Adverse Cardiovascular Events, Neutrophil-lymphocytes Ratio and Psychological Symptoms in Acute Coronary Syndrome in Intensive Cardiac Care Unit
Status: COMPLETED
Conditions: Acute Coronary Syndrome|Brief Supportive Psychotherapy|Intensive Cardiac Care Unit
Interventions: OTHER: Intervention group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: COMPARISON OF PERIOPERATIVE ANALGESIC EFFECTIVENESS OF PATIENTS WHO HAD FASIA ILIAC COMPARTMENT BLOCK AND 4IN1 BLOCK APPLIED IN TOTAL KNEE PROSTHESIS SURGERY
Status: NOT_YET_RECRUITING
Conditions: Pain, Postoperative
Interventions: OTHER: FICB|OTHER: 4 in 1 block
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Multi-part, Double Blind Study to Assess Safety, Tolerability and Efficacy of Tropifexor (LJN452) in PBC Patients
Status: COMPLETED
Conditions: Primary Biliary Cholangitis
Interventions: DRUG: Part 1: LJN452|DRUG: Part 1: Placebo|DRUG: Part 2: LJN452 Dose level 1|DRUG: Part 2: Placebo|DRUG: Part 2: LJN452 Dose level 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Extracorporeal Photopheresis in Early Diffuse Cutaneous Systemic Sclerosis
Status: NOT_YET_RECRUITING
Conditions: Diffuse Cutaneous Systemic Sclerosis
Interventions: DEVICE: Extracorporeal Photopheresis (ECP)|DRUG: UVADEX
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: INVESTIGATION OF THE EFFICACY OF FISTULA OBLITERATION BY STEAM ABLATION IN PERİANAL FISTULAS
Status: COMPLETED
Conditions: Anal Fistula
Interventions: PROCEDURE: steam ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase II, EvaluateBLEX 404 Combined With Gemcitabine Monotherapy With Pancreatic Cancer
Status: NOT_YET_RECRUITING
Conditions: Pancreatic Cancer
Interventions: DRUG: BLEX 404
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transcranial Direct Current Stimulation in a Home Treatment Setting for Major Depression
Status: RECRUITING
Conditions: Depression
Interventions: DEVICE: prefrontal tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cancer Occurrence and Outcome in Young Patients Undergoing Cancer Treatment at the Vanderbilt-Ingram Cancer Center
Status: TERMINATED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific|Unspecified Childhood Solid Tumor, Protocol Specific
Interventions: OTHER: medical chart review|OTHER: study of socioeconomic and demographic variables
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Ibuprofen, Paracetamol and Their Combination on Radical Oxygen Species (ROS) Production
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Ibuprofen|DRUG: Ibuprofen|DRUG: Paracetamol (acetaminophen) 1000 mg|DRUG: Paracetamol + ibuprofen
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Biodistribution and Pathophysiology Study of 11C-para-aminobenzoic Acid
Status: RECRUITING
Conditions: Renal Excretion|Bacterial Infections|Inflammatory Disease|Oncologic Disease
Interventions: COMBINATION_PRODUCT: 11C-para-aminobenzoic acid PET/CT|DRUG: Probenecid
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Dapagliflozin in Patients With Acute Heart Failure (DAPA-RESPONSE-AHF)
Status: COMPLETED
Conditions: Acute Heart Failure
Interventions: DRUG: Dapagliflozin 10mg Tab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness and Safety Trial of a New Ischemic Stroke Treatment Within 24 Hours From Stroke Onset (NEST-2)
Status: COMPLETED
Conditions: Ischemic Stroke
Interventions: DEVICE: NeuroThera® Laser System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lidocaine Patch Versus Celecoxib in Pain From Osteoarthritis of the Knee
Status: TERMINATED
Conditions: Osteoarthritis of the Knee
Interventions: DRUG: Lidoderm|DRUG: Celecoxib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Spinal Manipulation and Dry Needling Versus Conventional Physical Therapy in Patients With Cervicogenic Headache
Status: COMPLETED
Conditions: Cervicogenic Headaches
Interventions: OTHER: Dry Needling,Thrust Manipulation|OTHER: Exercise,Non-thrust Mobilization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Medicinal Nicotine for Preventing Cue Induced Craving
Status: COMPLETED
Conditions: Tobacco Use Disorder
Interventions: DRUG: Nicotine lozenge 4 mg|DRUG: Placebo lozenge
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Ceftaroline for Treatment of Hematogenously Acquired Staphylococcus Aureus Osteomyelitis in Children
Status: COMPLETED
Conditions: Hematogenously Acquired Staphylococcus Aureus Osteomyelitis|Bone Infection|Osteomyelitis
Interventions: DRUG: Ceftaroline Fosamil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of TAK-079 in People With Generalized Myasthenia Gravis
Status: COMPLETED
Conditions: Myasthenia Gravis
Interventions: DRUG: TAK-079|DRUG: TAK-079 Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Antihypertensive Efficacy of Valsartan and Enalapril After Missing One Dose
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Valsartan, Enalapril|DEVICE: Ambulatory blood pressure monitoring|PROCEDURE: Missing one dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Instant Message-delivered Early Psychological Intervention in Stroke Family Caregivers
Status: RECRUITING
Conditions: Stroke|Caregiver Burden|Mobile Phone Use
Interventions: BEHAVIORAL: iCBT-based EMI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: LASER and Radiofrequency for Treatment of Vaginal Vulvar Atrophy (VVA) in Women Treated for Breast Cancer (EPMLARF-arm2)
Status: RECRUITING
Conditions: Vaginal Atrophy|Vulva; Atrophy|Breast Cancer
Interventions: PROCEDURE: LASER|PROCEDURE: Micro Ablative Radiofrequency|DRUG: Promestriene
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I/II Open Label Single Centre Trial to Assess the Safety, Tolerability and Efficacy of Single Dose Neoadjuvant Anti-CLEVER-1 Antibody Bexmarilimab in Localised Renal Cell and Colon Carcinoma
Status: WITHDRAWN
Conditions: Carcinoma, Renal Cell|Carcinoma Colon
Interventions: DRUG: bexmarilimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Atracurium Mixed With Magnesium Sulfate Versus Atracurium Alone as Adjuvant to Lidocaine in IVRA
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: Lidocaine|DRUG: atracurium|DRUG: Mg sulphate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: ABC-04 a Study of Cisplatin, Gemcitabine and Selumetinib in Patients With Advanced Biliary Tract Cancer
Status: COMPLETED
Conditions: Biliary Tract Neoplasms|Cholangiocarcinoma|Gallbladder Neoplasms
Interventions: DRUG: selumetinib|DRUG: gemcitabine|DRUG: cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I/II Trial of VELCADE Plus Zevalin in Patients With Relapsed or Refractory Follicular Lymphoma
Status: TERMINATED
Conditions: Lymphoma
Interventions: DRUG: rituximab|DRUG: bortezomib|DRUG: Ibritumomab tiuxetan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Targeted Fortification of Pasteurized Donor Human Milk
Status: ACTIVE_NOT_RECRUITING
Conditions: Very Low Birth Weight Infant|Growth Failure|Donor Breast Milk
Interventions: DIETARY_SUPPLEMENT: Protein supplementation|OTHER: Analysis with Miris Human Milk Analyzer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Patient-Titrated Automated Intermittent Boluses of Local Anesthetic vs. a Continuous Infusion Via a Perineural Catheter for Postoperative Analgesia
Status: ENROLLING_BY_INVITATION
Conditions: Pain, Acute Postoperative|Trauma Injury
Interventions: DRUG: Continuous Infusion of ropivacaine 0.2%|DRUG: Titratable Automated Intermittent Boluses of ropivacaine 0.2%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prolonged Continuous ECG Monitoring Prior to Transcatheter Aortic Valve Implantation
Status: ACTIVE_NOT_RECRUITING
Conditions: Aortic Valve Stenosis|Arrythmia
Interventions: DEVICE: ECG monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Bioequivalence Study Comparing a Single Oral Intake of an Imported PROBUCOL Tablet(Lorelco) With a Marketed PROBUCOL Tablet(Chang Tai) in Chinese Healthy Volunteers
Status: COMPLETED
Conditions: Chinese Healthy Volunteers
Interventions: DRUG: Group A: imported Probucol ( Lorelco)|DRUG: Group B: Marketed Probucol ( Chang Tai)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Amoxicillin-Clavulanic Acid 400 Mg-57 mg Chewable Tablets Under Fasting Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: amoxicillin-clavulanic acid|DRUG: Augmentin®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effect of Topical Application of Black Pepper Essential Oil and Peripheral Catheter Insertion
Status: COMPLETED
Conditions: Vein; Spasm|Patient Satisfaction|Nurse Scope, Practice
Interventions: OTHER: Topical essential oil application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Examination of Musculoskeletal System Problems, Pain and Quality of Life Related to Working Conditions in Chiropractors
Status: COMPLETED
Conditions: The Investigation Will Examine Musculoskeletal Problems, Pain, and QoL in Chiropractors in Relation to Their Working Conditions
Interventions: OTHER: Survey completion
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Randomized, Double-Blind, Parallel-Group, Vehicle-Controlled Therapeutic Equivalence Study of Three Imiquimod Cream 5% Treatments for Patients With Actinic Keratosis
Status: COMPLETED
Conditions: Actinic Keratosis
Interventions: DRUG: Imiquimod 5%: manufactured by Apotex|DRUG: Adara 5% Cream US|DRUG: Adara 5% Cream Canada|DRUG: Imiquimod Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Acetaminophen and Aspirin Versus Placebo in the Acute Treatment of Migraine
Status: COMPLETED
Conditions: Acute Migraine
Interventions: DRUG: Acetaminophen 250 mg and Aspirin 250 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Entertainment Media to Deliver Educational Messages About Mammography in Saudi Arabia
Status: COMPLETED
Conditions: Breast Cancer|Behavior
Interventions: BEHAVIORAL: You-Tube Video: Elissa's EE song|BEHAVIORAL: Active Comparator: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Mindfulness Training in Nurses and Its Effect on Work Stress
Status: COMPLETED
Conditions: Nursing Caries|Consciousness, Level Altered
Interventions: BEHAVIORAL: Conscious Awareness-Based Educatıon|BEHAVIORAL: Stress coping training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Impact of PCSK9 Inhibition on Clinical Outcome in Patients During the Inflammatory Stage of the COVID-19
Status: COMPLETED
Conditions: Sars-CoV-2 Infection
Interventions: DRUG: Evolocumab|DRUG: Saline solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT