pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Application of Health Education Path of Traditional Chinese Medicine Nursin
Status: COMPLETED
Conditions: Acute Myeloid Leukemia
Interventions: OTHER: traditional Chinese medicine health education standard path|OTHER: The contents of the health intervention mainly included:Graphic and text education|OTHER: The contents of the health intervention mainly included:Language education|OTHER: The contents of the health intervention mainly included:Psychological education|OTHER: The contents of the health intervention mainly included:Dietary education|OTHER: The contents of the health intervention mainly included:Complication education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparative Effects Of High Intensity Spinal Decompression Exercises And Eldoa In Patients Of Lumbar Radiculopathy
Status: COMPLETED
Conditions: Lumbar Radiculopathy
Interventions: OTHER: High Intensity Spinal Decompression Exercises|OTHER: Eldoa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Parasitic Ulcer Treatment Trial Pilot
Status: ACTIVE_NOT_RECRUITING
Conditions: Acanthamoeba Keratitis
Interventions: DRUG: Chlorhexidine|DRUG: Povidone-Iodine|DRUG: Prednisolone Sodium Phosphate|DRUG: Hydroxypropyl Methylcellulose|DRUG: Prednisolone Sodium Phosphate|DRUG: Hydroxypropyl Methylcellulose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Mobile Phone-based Intervention on Dementia Patients' Caregivers in Vietnam
Status: ACTIVE_NOT_RECRUITING
Conditions: Dementia
Interventions: OTHER: Information including knowledge and skills related to dementia patient care|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Combination Chemotherapy Plus Bevacizumab in Treating Patients With Metastatic Prostate Cancer
Status: COMPLETED
Conditions: Adenocarcinoma of the Prostate|Hormone-resistant Prostate Cancer|Recurrent Prostate Cancer|Stage IV Prostate Cancer
Interventions: DRUG: estramustine phosphate sodium|DRUG: docetaxel|BIOLOGICAL: bevacizumab|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Preoperative Weekly Paclitaxel and Carboplatin With Lapatinib (Tykerb®) in Patients With ErbB2-Positive Stage I-III Breast Cancer
Status: UNKNOWN
Conditions: ErbB2-Positive Stage I-III Breast Cancer
Interventions: DRUG: paclitaxel/carboplatin/lapatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mid-morning Gel Snacks on Subjective Appetite, Glycemic and Insulin Responses, and Food Intake
Status: COMPLETED
Conditions: Satiety|Food Intake
Interventions: OTHER: Control snack|OTHER: Maltodextrin snack|OTHER: Whey protein snack|OTHER: Oat snack|OTHER: Coconut oil snack|OTHER: Snack skipping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety Study of Products Based on Tribulus Terrestris, L. in Men With Oligospermia
Status: NOT_YET_RECRUITING
Conditions: Oligospermia
Interventions: DRUG: Tribulus terrestris|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Treatments of Acquired Apraxia of Speech
Status: COMPLETED
Conditions: Aphasia|Apraxia of Speech|Stroke
Interventions: BEHAVIORAL: Sound Production Treatment - Blocked|BEHAVIORAL: Sound Production Treatment - Random
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Safety, Tolerability, and Pharmacokinetic Characteristics of HLX51 in Patients With Solid Tumor or Lymphoma
Status: NOT_YET_RECRUITING
Conditions: Solid Tumor, Adult Lymphoma
Interventions: DRUG: HLX51
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Different Surgical Treatments for Severe Ptosis Correction
Status: UNKNOWN
Conditions: Ptosis, Eyelid
Interventions: PROCEDURE: Levator muscle and tarsus resection|PROCEDURE: Frontalis flap
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Stellate Ganglion Block for Prevention of Post Mastectomy Depression
Status: RECRUITING
Conditions: Mastectomy|Pain, Acute|Pain, Chronic
Interventions: PROCEDURE: Stellate gangalion block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Clinical Trial Evaluating ITI-007 as an Adjunctive Therapy to Lithium or Valproate for the Treatment of Bipolar Depression
Status: COMPLETED
Conditions: Bipolar Depression
Interventions: DRUG: Lumateperone (ITI-007)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Lung Ultrasound and Chest Radiography for Acute Dyspnea
Status: COMPLETED
Conditions: Dyspnea|Congestive Heart Failure
Interventions: OTHER: Lung Ultrasound|OTHER: Chest Radiography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Feasibility of Improving Glycemia With Heat Therapy to Prevent AD
Status: ENROLLING_BY_INVITATION
Conditions: Healthy Aging|Alzheimer Disease|Metabolic Disease
Interventions: OTHER: Water Immersion Heat Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Splanchnic Nerve Anesthesia in Heart Failure
Status: COMPLETED
Conditions: Heart Failure
Interventions: PROCEDURE: splanchnic nerve anesthesia with a local anesthetic|DRUG: regional nerve block with a local anesthetic (Lidocaine)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cognitive Behavioural Therapy for Complicated Grief Reactions in Old Age
Status: RECRUITING
Conditions: Bereavement|Prolonged Grief Disorder|Depression|Anxiety|Posttraumatic Stress Disorder
Interventions: BEHAVIORAL: Group-based Cognitive Behavioural Therapy for Complicated Grief Reactions|BEHAVIORAL: Individually delivered Cognitive Behavioural Therapy for Complicated Grief Reactions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stent-related Symptoms Comparison: Polaris Loop vs Vortek Double-J Stents
Status: COMPLETED
Conditions: Symptoms and Signs|Pain|Renal Calculi
Interventions: OTHER: USSQ questionnaire administration after RIRS.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: fMRI-neuronavigated rTMS Treatment for Symptoms of Depression Associated With Concussive TBI in the Military Population
Status: TERMINATED
Conditions: Traumatic Brain Injury|Concussion, Mild|Depressive Symptoms
Interventions: DEVICE: Active: rTMS|DEVICE: Sham: rTMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cross Education in Patients With Sensorimotor Impairment
Status: UNKNOWN
Conditions: Neurological Disorder
Interventions: DEVICE: Rehabit-Tec System|DEVICE: Rehabit-Tec System|BEHAVIORAL: conventional exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transthoracic Needle Biopsy Using 3D Printed Navigational Template: A Phase I Feasibility Trial
Status: COMPLETED
Conditions: Lung Neoplasms
Interventions: DEVICE: navigational template
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Study of Dexamethasone-Allantoin-Metronidazole (DAM) Solution in the Treatment of Post-Operative Ileus (POI)
Status: UNKNOWN
Conditions: Postoperative Ileus
Interventions: DRUG: DAM|DRUG: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Improving Vocational Outcomes in Arthritis
Status: COMPLETED
Conditions: Arthritis|Musculoskeletal Diseases|Rheumatic Diseases
Interventions: BEHAVIORAL: Vocational counseling intervention|BEHAVIORAL: Reading materials for control participants|BEHAVIORAL: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy and Radiation Therapy in Treating Patients With Stage III or Stage IV Head and Neck Cancer
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: DRUG: Taxotere|PROCEDURE: Surgery|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Erlotinib in Treating Patients With Locally Advanced or Metastatic Papillary Renal Cell Cancer
Status: COMPLETED
Conditions: Recurrent Renal Cell Cancer|Stage III Renal Cell Cancer|Stage IV Renal Cell Cancer
Interventions: DRUG: erlotinib hydrochloride|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Roadsaver Stent Used in Conjunction With the Nanoparasol Embolic Protection System for Carotid Artery Stenosis
Status: ACTIVE_NOT_RECRUITING
Conditions: Carotid Artery Stenosis
Interventions: DEVICE: Roadsaver™ Carotid Artery Stent Device|DEVICE: Nanoparasol® Embolic Protection System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Examine the Effect of Reconval K1 Cream to Prevent Skin Toxicity From EGFRI
Status: COMPLETED
Conditions: Rash Due to Epidermal Growth Factor Receptor Inhibitors
Interventions: DRUG: RECONVAL CREAM|DRUG: PLACEBO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Virtual Reality on Pain, Anxiety, and Vital Signs of the Patients Undergoing Port Catheter Implantation
Status: COMPLETED
Conditions: Pain|Anxiety|Blood Pressure|Body Temperature Changes
Interventions: OTHER: Virtual Reality Distraction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Assess the Relative Oral Bioavailability and Food Effect of Single-dose of JNJ-64417184 in Healthy Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: JNJ-64417184 600 (Oral Tablet Formulation)|DRUG: JNJ-64417184 (Oral Suspension Formulation)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: New Diagnostic Tools in the Evaluation of the Posterior Compartment of the Women Pelvic Floor
Status: NOT_YET_RECRUITING
Conditions: Anal Incontinence|Obstructive Defecation
Interventions: DEVICE: Impedance Planimetry, High-definition anorectal manometry and Pelvic Floor Ultrasonography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Two-Part 26-Week Study of Etoricoxib as Treatment for Ankylosing Spondylitis (AS) (MK-0663-108)
Status: COMPLETED
Conditions: Spondylitis, Ankylosing
Interventions: DRUG: Part I - etoricoxib 60 mg|DRUG: Part I - etoricoxib 90 mg|DRUG: Part I- naproxen 1000 mg|DRUG: Part I - Placebo to naproxen 500 mg|DRUG: Part II- etoricoxib 60 mg|DRUG: Part II- etoricoxib 90 mg|DRUG: Part II- naproxen 1000 mg|DRUG: Part I - Placebo to etoricoxib 60 mg|DRUG: Part I - Placebo to etoricoxib 90 mg|DRUG: Part II- Placebo to etoricoxib 60 mg|DRUG: Part II - Placebo to etoricoxib 90 mg|DRUG: Part II- Placebo to naproxen 500 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Kinesiotape Treatment for Postoperative Edema After Joint Replacement Surgery of the Knee- The KNEETAPE Study
Status: COMPLETED
Conditions: Postoperative Edema
Interventions: DEVICE: lymphtaping using Easytape®|PROCEDURE: compression treatment|DEVICE: sham taping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Administration of Donor MultiTAA-Specific T Cells for ALL
Status: ACTIVE_NOT_RECRUITING
Conditions: Leukemia, Lymphoblastic (Acute)
Interventions: BIOLOGICAL: MultiTAA-specific T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vasopressin and Epinephrine Versus Epinephrine Alone in Cardiac Arrest
Status: COMPLETED
Conditions: Cardiac Arrest
Interventions: DRUG: epinephrine (1 mg/1 mL)|DRUG: arginine-vasopressin (40 UI/2 mL)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Quantitative Study to Assess the Construct Validity of the Prescription Opioid Misuse and Abuse Questionnaire
Status: COMPLETED
Conditions: Opioid-Related Disorders|Opiate Addiction|Narcotic Abuse|Drug Abuse
Interventions: OTHER: Prescription Opioid Misuse and Abuse Questionnaire (POMAQ)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Capacity of Biofilm Removal and Gingival Abrasion After Utilization Medium and Soft Toothbrushes
Status: COMPLETED
Conditions: Biofilm Removal|Gingival Abrasion
Interventions: DEVICE: Two kind toothbrushes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Open-Label Extension Trial of PDE4 Inhibition With Roflumilast for the Management of Plaque Psoriasis
Status: COMPLETED
Conditions: Chronic Plaque Psoriasis
Interventions: DRUG: Topical roflumilast
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dovitinib in Neuroendocrine Tumors
Status: COMPLETED
Conditions: Advanced Metastatic Paraganglioma|Advanced Metastatic Pheochromocytoma|Recurrent Paraganglioma|Recurrent Pheochromocytoma|Unresectable Paraganglioma|Unresectable Pheochromocytoma
Interventions: DRUG: Dovitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Posterior Tibial Nerve PRF vs Intralesional RFT for Painful Calcaneal Spur and Plantar Fasciitis
Status: COMPLETED
Conditions: Heel Spur|Plantar Fascitis
Interventions: PROCEDURE: ultrasound-guided posterior tibial nerve pulsed radiofrequency|PROCEDURE: fluoroscopy-guided intralesional radiofrequency thermocoagulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pregabalin Gel in Reducing Post-operative Tooth Sensitivity Surgery Caused by Bleaching With 35% Hydrogen Peroxide
Status: NOT_YET_RECRUITING
Conditions: Tooth Bleaching|Sensitivity, Tooth
Interventions: DRUG: pregabalin gel|DRUG: gel with 5% potassium nitrate and 2% sodium fluoride|OTHER: Placebo gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Targeted Intra-Operative Radiotherapy for the Management of Ductal Carcinoma In-Situ of the Breast
Status: TERMINATED
Conditions: Breast Cancer
Interventions: RADIATION: Intraoperative radiotherapy|DEVICE: Intraoperative radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Therapy for Depression With Co-occurring Panic or Anxiety Symptoms
Status: COMPLETED
Conditions: Depression|Anxiety Disorders|Panic Disorder
Interventions: BEHAVIORAL: Interpersonal Psychotherapy (IPT)|BEHAVIORAL: IPT for Depression with Co-occurring Panic and Anxiety Symptoms (IPT-PS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tailored Smoking Cessation Treatment for LIVE FOR LIFE® Participants
Status: TERMINATED
Conditions: Cigarette Smoking|Nicotine Dependence
Interventions: DRUG: varenicline (Chantix)|DRUG: bupropion (Zyban)|DRUG: nicotine patches
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Short Term Adrenal Suppression on Androgen Overproduction in Overweight Girls With Androgen Excess
Status: WITHDRAWN
Conditions: Hyperandrogenemia|Obesity|Polycystic Ovary Syndrome
Interventions: DRUG: Hydrocortisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Mechanisms of Change, Motivation, and Treatment Outcome in Alcohol Dependence - Posttraumatic Stress Disorder
Status: COMPLETED
Conditions: Alcohol Dependence|Posttraumatic Stress Disorder
Interventions: BEHAVIORAL: Trauma-focused exposure therapy|BEHAVIORAL: Motivational enhancement + trauma-focused exposure therapy|BEHAVIORAL: Healthy lifestyles sessions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Continuous Versus Interval Walking Training in Patients With COPD - a Pilot Study
Status: COMPLETED
Conditions: Chronic Obstructive Airway Disease
Interventions: DEVICE: Treadmill|OTHER: walking training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparison of User-adjusted and Audiologist-adjusted Hearing Amplification
Status: WITHDRAWN
Conditions: Hearing Loss
Interventions: DEVICE: Hearing aid fitting technique- audiologist or user-adjusted
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vulvovaginal Candidiasis in Canadian Females
Status: RECRUITING
Conditions: Candidiasis, Vulvovaginal
Interventions: DRUG: Fluconazole 150 mg|DRUG: Boric Acid Supp,Vag
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Brentuximab Vedotin and Combination Chemotherapy in Treating Patients With Stage II-IV HIV-Associated Hodgkin Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: AIDS-Related Hodgkin Lymphoma|Ann Arbor Stage II Hodgkin Lymphoma|Ann Arbor Stage IIA Hodgkin Lymphoma|Ann Arbor Stage IIB Hodgkin Lymphoma|Ann Arbor Stage III Hodgkin Lymphoma|Ann Arbor Stage IIIA Hodgkin Lymphoma|Ann Arbor Stage IIIB Hodgkin Lymphoma|Ann Arbor Stage IV Hodgkin Lymphoma|Ann Arbor Stage IVA Hodgkin Lymphoma|Ann Arbor Stage IVB Hodgkin Lymphoma|Classic Hodgkin Lymphoma|HIV Infection
Interventions: DRUG: Brentuximab Vedotin|DRUG: Dacarbazine|DRUG: Doxorubicin Hydrochloride|OTHER: Pharmacological Study|DRUG: Vinblastine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Efficacy and Safety Study of JNJ-38518168 in Adult Participants With Rheumatoid Arthritis
Status: TERMINATED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: JNJ 38518168|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Pharmacokinetics, Safety, and Tolerability of Bedaquiline in Infants, Children, and Adolescents With Multidrug-Resistant Tuberculosis, Living With or Without HIV
Status: ACTIVE_NOT_RECRUITING
Conditions: Tuberculosis|HIV
Interventions: DRUG: Bedaquiline
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lymphatic Function in Patients With a Fontan Circulation From Brazil
Status: COMPLETED
Conditions: Univentricular Heart|Lymphatic Abnormalities|Lymphatic Edema
Interventions: DIAGNOSTIC_TEST: Near-Infrared Fluorescence imaging|DIAGNOSTIC_TEST: Strain Gauge Plethysmography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Fertility-sparing Therapy for Patients With Stage IA Endometrial Cancer
Status: RECRUITING
Conditions: Endometrial Neoplasms|Endometrial Neoplasm Malignant|Endometrial Neoplasm Malignant Stage I|Carcinoma, Endometrioid|Fertility Preservation
Interventions: COMBINATION_PRODUCT: Indication-extended Fertility-sparing Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized Phase 2 Study of ARQ 197 Versus Gemcitabine in Treatment-Naïve Patients With Unresectable Locally Advanced or Metastatic Pancreatic Adenocarcinoma
Status: COMPLETED
Conditions: Pancreatic Neoplasms
Interventions: DRUG: ARQ 197|DRUG: gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Role of Local Tranexamic Acid on Periorbital Oculoplastic Surgery
Status: WITHDRAWN
Conditions: Eyelid Diseases|Periorbital Disorder|Hemorrhage|Surgical Blood Loss
Interventions: DRUG: Tranexamic acid|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Randomized Trial of Standard vs ClearWay-infused Abciximab and Thrombectomy for Myocardial Infarction
Status: UNKNOWN
Conditions: ST-elevation Myocardial Infarction
Interventions: DEVICE: ClearWay RX catheter|DRUG: Abciximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tight Caloric Control in the Cachectic Oncologic Patient (TiCaCONCO or CoCooN)
Status: COMPLETED
Conditions: Metabolism and Nutrition Disorder
Interventions: DIETARY_SUPPLEMENT: Nutrition Therapy|DIETARY_SUPPLEMENT: Control Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A First Time in Human Study to Evaluate the Safety and Tolerability of GSK3996401 Following Dosing With GSK4347859 in Healthy Participants
Status: NOT_YET_RECRUITING
Conditions: Systemic Lupus Erythematosus
Interventions: DRUG: GSK4347859|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Specific Strength Training Combined With Static Stretching of the Posterior Neck in Office Workers With Chronic Neck Pain: A Clinical Trial
Status: NOT_YET_RECRUITING
Conditions: Neck Pain|Work Injury
Interventions: OTHER: specific strength training with static neck stretching|OTHER: Specific Strength Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of JNJ-73763989, Pegylated Interferon Alpha-2a and Nucleos(t)Ide Analogs in Participants With Chronic Hepatitis B Virus Infection
Status: TERMINATED
Conditions: Hepatitis B, Chronic
Interventions: DRUG: JNJ-73763989|DRUG: PegIFN-alpha-2a|DRUG: Tenofovir disoproxil|DRUG: TAF|DRUG: ETV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Empagliflozin and Anakinra for the Treatment of Postprandial Hypoglycemia in Patients With Prediabetes
Status: ACTIVE_NOT_RECRUITING
Conditions: Postprandial Hypoglycemia
Interventions: DRUG: empagliflozin|DRUG: anakinra|OTHER: saline subcutaneous (s.c.) (placebo)|OTHER: tablet per oral (p.o.) (placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Guided Relaxation Training for the Reduction of Self-Reported Stress in Individuals With Newly Diagnosed Breast Cancer
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: OTHER: GRT (Guided Relaxation Training)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Third Dose of Moderna COVID-19 Vaccine in Transplant Recipients
Status: COMPLETED
Conditions: Vaccine Response Impaired|Immune Suppression|Covid19
Interventions: BIOLOGICAL: mRNA-1273 vaccine|OTHER: Normal Saline Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of a Daily Disposable Novel Multifocal Contact Lens in a Myopic Population; Part 2
Status: COMPLETED
Conditions: Visual Acuity
Interventions: DEVICE: JJVC Investigational Multifocal Contact Lens|DEVICE: Dailies Total 1® Multifocal Contact Lens
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Comparative Effects of Myofascial Stretch and Contract-relax in Children With Spastic cp
Status: COMPLETED
Conditions: Cerebral Palsy
Interventions: OTHER: MYOFASCIAL STRETCH|OTHER: CONTRACT-RELAX TECHNIQUE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Phase 1 Clinical Study of NXP800 in Subjects With Advanced Cancers and Expansion in Subjects With Ovarian Cancer
Status: RECRUITING
Conditions: Advanced Solid Tumor|Ovarian Cancer|Ovarian Clear Cell Carcinoma|Ovarian Clear Cell Tumor|Ovarian Clear Cell Adenocarcinoma|Ovarian Endometrioid Adenocarcinoma|Ovarian Endometrioid Tumor|ARID1A Gene Mutation
Interventions: DRUG: NXP800
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Palliative Care in Advanced Lung and Gastrointestinal Malignancies
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer|Small Cell Lung Cancer|Mesothelioma|Esophageal Cancer|Gastric Cancer|Liver Cancer|Pancreatic Cancer
Interventions: OTHER: early palliative care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Assessment of Hemodynamic Response During Intubation Between Rigid Laryngoscopy and Track Light in Coronary Patients
Status: COMPLETED
Conditions: Coronary Disease Undergoing CABG
Interventions: PROCEDURE: laryngoscopy|PROCEDURE: track light
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Nab-Paclitaxel and Carboplatin Plus Necitumumab (LY3012211) in Participants With Stage IV Squamous NSCLC
Status: COMPLETED
Conditions: Carcinoma, Non-Small Cell Lung Cancer (NSCLC)
Interventions: DRUG: Necitumumab|DRUG: Nab-Paclitaxel|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial of HS-10511 in Healthy Subjects
Status: NOT_YET_RECRUITING
Conditions: Hypertrophic Cardiomyopathy
Interventions: DRUG: HS-10511 Tablets|DRUG: HS-10511 Tablets Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigating the Possible Link Between Habitual Diet, Physical Activity, Sleeping Patterns, Obesity Status and Age With Gut Bacterial Composition, Gut Barrier Function, Metabolic Endotoxemia, Systemic Inflammation and Glycaemic Control.
Status: UNKNOWN
Conditions: Obesity|Metabolic Syndrome|Insulin Resistance
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of Cross-Linked Polyelectrolyte (CLP) in Healthy Volunteers
Status: COMPLETED
Conditions: Basic Science: Safety, Tolerability, Efficacy of CLP
Interventions: DRUG: Cross-Linked Polyelectrolyte (CLP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Different Fractionation Schedules of Radiotherapy to the Primary Tumour in Metastatic Hormone Sensitive Prostate Cancer
Status: RECRUITING
Conditions: Prostate Cancer|Radiotherapy Side Effect|Metastatic Cancer
Interventions: RADIATION: Moderate hypo-fractionation|RADIATION: Ultra-hypo-fractionation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Intravascular Uptake and Pain Perception During Epidural Injection Using 22 Gauge vs 25 Gauge Needle
Status: COMPLETED
Conditions: Pain|Needle Injury
Interventions: DEVICE: 22-gauge needle|DEVICE: 25-gauge needle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Clinical Efficacy and Safety of Iguratimod in RA and Early RA Patients for 6 Months Treatment
Status: COMPLETED
Conditions: Arthritis, Rheumatoid
Interventions: DRUG: Iguratimod|DRUG: MTX|DRUG: HCQ|DRUG: Pred
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transcutaneous Electrical Nerve Stimulation for Post-Cesarean Pain Control
Status: RECRUITING
Conditions: Transcutaneous Electric Nerve Stimulation|Analgesia|Cesarean Section
Interventions: DEVICE: Transcutaneous electrical nerve stimulation (TENS) unit|DEVICE: Placebo transcutaneous electrical nerve stimulation (TENS) unit
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Fluid Resuscitation in Shocked Patients by Electrical Cardiometry in Comparison to Transthoracic Echocardiography.
Status: COMPLETED
Conditions: Fluid Resuscitation|Electrical Cardiometry|Transthoracic Echocardiography|Shock
Interventions: DEVICE: Assessment of fluid responsiveness by electrical cardiometry
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Safety, Tolerability and Pharmacokinetics of Medical Grade Cannabis (MGC) Orally Disintegrating Tablets With Buccal Sativex®, in Healthy Adult Volunteers
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: OWCP Orally Disintegrating Tablet|DRUG: Sativex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: the Effects of Different Treatment Schemes on Cognitive Function of Patients With Idiopathic Membranous Nephropathy
Status: RECRUITING
Conditions: Mild Cognitive Impairment|Idiopathic Membranous Nephropathy
Interventions: DRUG: prednisone,methylprednisone and cyclophosphamide|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Open-label Study to Evaluate the Relative Bioavailability of Samatasvir (IDX184) and Food Effect in Healthy Male Participants (MK-2355-006)
Status: COMPLETED
Conditions: Hepatitis C
Interventions: DRUG: Samatasvir tablet|DRUG: Samatasvir capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Frailty Intervention Trial in End-Stage Patients on Dialysis
Status: ACTIVE_NOT_RECRUITING
Conditions: Hemodialysis Complication|Nutritional Deficiency|Physical Activity
Interventions: BEHAVIORAL: Multi-disciplinary intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Panobinostat and Carfilzomib in Treating Participants With Relapsed or Refractory Multiple Myeloma
Status: COMPLETED
Conditions: Non-Secretory Plasma Cell Myeloma|Plasmacytosis|Recurrent Plasma Cell Myeloma|Refractory Plasma Cell Myeloma
Interventions: DRUG: Carfilzomib|DRUG: Panobinostat
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: E-health Cognitive Behavioral Therapy in Women Treated by in Vitro Fertilization (IVF)
Status: COMPLETED
Conditions: Depression|Anxiety|Infertility
Interventions: BEHAVIORAL: Digicoach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Early Viscosupplementation After ACL Reconstruction: a Randomized Controlled Trial
Status: COMPLETED
Conditions: Complete Tear, Knee, Anterior Cruciate Ligament
Interventions: BIOLOGICAL: viscosupplementation|OTHER: Placebo group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect and Safety of Moxibustion Therapy for Overactive Bladder Patients
Status: COMPLETED
Conditions: Overactive Bladder|Hyperthermia|Urinary Frequency or Urgency Adverse Event|Lower Urinary Tract Symptoms
Interventions: DEVICE: moxibustion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PD-L1 ImagiNg to prediCt Durvalumab Treatment Response in HNSCC
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: DIAGNOSTIC_TEST: PD-L1 imaging|DRUG: Durvalumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Sirolimus and Cyclophosphamide in Metastatic or Unresectable Myxoid Liposarcoma and Chondrosarcoma
Status: COMPLETED
Conditions: Conventional Chondrosarcoma|Myxoid Liposarcoma|Mesenchymal Chondrosarcoma|Dedifferentiated Chondrosarcoma
Interventions: DRUG: sirolimus and cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Laryngoscopy for Neonatal and Infant Airway Management wIth Supplemental Oxygen at Different Flow Rates (OPTIMISE-2)
Status: RECRUITING
Conditions: Airway Management
Interventions: DEVICE: Low-flow nasal supplemental oxygen with a conventional nasal cannula during tracheal intubation with the C-MAC video laryngoscope|DEVICE: High-flow nasal supplemental oxygen (Fisher & Paykel, Auckland, New Zealand) during tracheal intubation with the C-MAC video laryngoscope
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A phase4 Clinical Study to Evaluate the Safety and Efficacy of Switching to Tenofovir Disoproxil From Tenofovir Disoproxil Fumarate in Patients With Chronic Hepatitis B
Status: COMPLETED
Conditions: Chronic Hepatitis B
Interventions: DRUG: Tenofovir disoproxil 245mg|DRUG: Tenofovir disoproxil fumarate 300mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the mTOR Inhibitor Temsirolimus (CCI-779) to Treat Ovarian Cancer With CA125 Only Relapse
Status: TERMINATED
Conditions: Ovarian Cancer
Interventions: DRUG: Temsirolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of ALKS 8700 in Adults With Relapsing Remitting Multiple Sclerosis (MS) EVOLVE-MS-1
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DRUG: ALKS 8700
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Software to Prevent Delirium (PREVEDEL) in Hospitalized Older Adults
Status: UNKNOWN
Conditions: Delirium|Confusion|Neurobehavioral Manifestations|Neurologic Manifestations
Interventions: OTHER: Prevention software|OTHER: Placebo|OTHER: Implement a program of non-pharmacological interventions to prevent delirium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Acupressure Versus Traditional Treatment on Reducing Ankle Edema During Pregnancy
Status: COMPLETED
Conditions: Gestational Edema
Interventions: OTHER: advices|OTHER: Traditional physical therapy|OTHER: Acupressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: CPI-613, Bendamustine Hydrochloride, and Rituximab in Treating Patients With Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma
Status: TERMINATED
Conditions: B-cell Adult Acute Lymphoblastic Leukemia|B-cell Chronic Lymphocytic Leukemia|Cutaneous B-cell Non-Hodgkin Lymphoma|Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue|Intraocular Lymphoma|Nodal Marginal Zone B-cell Lymphoma|Recurrent Adult Acute Lymphoblastic Leukemia|Recurrent Adult Burkitt Lymphoma|Recurrent Adult Diffuse Large Cell Lymphoma|Recurrent Adult Diffuse Mixed Cell Lymphoma|Recurrent Adult Diffuse Small Cleaved Cell Lymphoma|Recurrent Adult Grade III Lymphomatoid Granulomatosis|Recurrent Adult Immunoblastic Large Cell Lymphoma|Recurrent Adult Lymphoblastic Lymphoma|Recurrent Grade 1 Follicular Lymphoma|Recurrent Grade 2 Follicular Lymphoma|Recurrent Grade 3 Follicular Lymphoma|Recurrent Mantle Cell Lymphoma|Recurrent Marginal Zone Lymphoma|Recurrent Mycosis Fungoides/Sezary Syndrome|Recurrent Small Lymphocytic Lymphoma|Refractory Chronic Lymphocytic Leukemia|Refractory Hairy Cell Leukemia|Small Intestine Lymphoma|Splenic Marginal Zone Lymphoma|Testicular Lymphoma|Waldenström Macroglobulinemia
Interventions: DRUG: 6,8-bis(benzylthio)octanoic acid|DRUG: bendamustine hydrochloride|BIOLOGICAL: rituximab|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Roflumilast in Japanese Patients With Bronchial Asthma (20 to 70 y) (APTA-2217-05)
Status: COMPLETED
Conditions: Bronchial Asthma
Interventions: DRUG: Roflumilast
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Analgesic Efficacy of Morphine Alone or Combined With Paracetamol and/or Ibuprofen for Long-bones Fractures in Children
Status: COMPLETED
Conditions: Pain|Long-bone Fractures
Interventions: DRUG: Paracetamol|DRUG: Ibuprofen|DRUG: paracetamol + ibuprofen|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Predicting Model Based on Evidence-based Pathological Diagnose Criteria for RCC Tumor Thrombus With IVC Wall Invasion
Status: RECRUITING
Conditions: Carcinoma, Renal Cell|Tumor Thrombus|Neoplasm Invasiveness|Inferior Vena Cava Interruption
Interventions: DIAGNOSTIC_TEST: Vascular wall invaded
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: MultiStem® Administration for Stroke Treatment and Enhanced Recovery Study
Status: UNKNOWN
Conditions: Ischemic Stroke
Interventions: BIOLOGICAL: MultiStem|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Levator Resection with3 Point Fixation Versus 2 Point Fixation Tucking for Congenital Ptosis
Status: COMPLETED
Conditions: Congenital Ptosis
Interventions: PROCEDURE: levator resection|PROCEDURE: levator tucking
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CEUS Evaluation of Bowel Perfusion in Necrotizing Enterocolitis
Status: RECRUITING
Conditions: Necrotizing Enterocolitis of Newborn|Bowel Ischemic
Interventions: DRUG: Sulfur hexafluoride lipid-type A microspheres
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effect of Wheat Germ on Gastrointestinal Discomfort, Blood Cholesterol and Postprandial Glycaemic Response
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DIETARY_SUPPLEMENT: wheat bread with wheat germ|DIETARY_SUPPLEMENT: wheat bread without wheat germ
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Lung Function, Exercise Capacity and Health-Related Quality of Life After Severe COVID-19
Status: COMPLETED
Conditions: COVID-19|SARS-CoV-2 Infection
Interventions: DIAGNOSTIC_TEST: Lung Function tests|DIAGNOSTIC_TEST: Exercise capacity|DIAGNOSTIC_TEST: Exercise physiology|DIAGNOSTIC_TEST: Health-related quality of life|DIAGNOSTIC_TEST: Respiratory symptoms, symptoms of anxiety and depression, and post-traumatic stress screening
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Chronic Remote Ischaemic Preconditioning on Blood Pressure in Older Adults
Status: RECRUITING
Conditions: Hypertension|Vascular Diseases
Interventions: DEVICE: Remote Ischaemic Preconditioning|DEVICE: Sham Remote Ischaemic Preconditioning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability of Tozadenant as Adjunctive Therapy in Levodopa-Treated Patients With Parkinson's Disease.
Status: TERMINATED
Conditions: Idiopathic Parkinson Disease
Interventions: DRUG: Tozadenant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Weight-bearing Diagnostics in Acute Lisfranc Injury: CT vs X-ray
Status: ACTIVE_NOT_RECRUITING
Conditions: Lisfranc Injury|Foot Sprain
Interventions: PROCEDURE: Conservative treatment|PROCEDURE: Minimally invasive stabilization
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effects of a Culturally-sensitive Theory-driven Advance Care Planning (ACP) Game Among Chinese Older Adults
Status: COMPLETED
Conditions: Advance Care Planning|Game|Older Adults
Interventions: BEHAVIORAL: ACP game|BEHAVIORAL: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Prostate-cancer Treatment Using Stereotactic Radiotherapy for Oligometastases Ablation in Hormone-sensitive Patients
Status: RECRUITING
Conditions: Oligometastatic Hormone Sensitive Prostate Cancer
Interventions: RADIATION: Stereotactic Body Radiotherapy (SBRT) + Standard of care|DRUG: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess Safety and Efficacy of ASP1941 in Combination With Nateglinide in Type 2 Diabetic Patients
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: ipragliflozin|DRUG: nateglinide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reducing Post-discharge Adverse Drug Events Amongst the Elderly: a Multi-centre Electronic Deprescribing Intervention
Status: COMPLETED
Conditions: Adverse Drug Event
Interventions: OTHER: Deprescribing opportunities
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: An Open-label Study to Assess Safety and Efficacy of SZC in Paediatric Patients With Hyperkalaemia
Status: RECRUITING
Conditions: Hyperkalaemia
Interventions: DRUG: Sodium Zirconium Cyclosilicate (SZC) Reduced Dose Level|DRUG: Sodium Zirconium Cyclosilicate (SZC) Dose Level 1 (DL1)|DRUG: Sodium Zirconium Cyclosilicate (SZC) Dose Level 2 (DL2)|DRUG: Sodium Zirconium Cyclosilicate (SZC) Dose Level 3 (DL3)|DRUG: Sodium Zirconium Cyclosilicate (SZC) Dose During 28 Day Maintenance Phase
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Functional Magnetic Resonance Imaging of Opioid Withdrawal in Healthy Human Volunteers
Status: COMPLETED
Conditions: Substance-Related Disorders
Interventions: DRUG: Ondansetron
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT