pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Gut Hormones and Bone Remodeling in Humans (KS-2)
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: GLP-2|OTHER: GIP|OTHER: GLP-2+GIP|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Safety of ON 01910.Na in Myelodysplastic Syndrome (MDS) Patients With Trisomy 8 or Classified as Intermediate-1, -2 or High Risk
Status: COMPLETED
Conditions: Myelodysplastic Syndrome
Interventions: DRUG: ON 01910.Na|DRUG: ON 01910.Na
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Humanized 3F8 Monoclonal Antibody (Hu3F8) in Patients With High-Risk Neuroblastoma and GD2-Positive Tumors
Status: COMPLETED
Conditions: Neuroblastoma
Interventions: BIOLOGICAL: Humanized 3F8 Monoclonal Antibody (Hu3F8)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Predictive Factors for Survival in Aggressive Meningiomas
Status: RECRUITING
Conditions: Meningioma|Meningioma Atypical|Anaplastic Meningioma
Interventions: DIAGNOSTIC_TEST: Biological biomarker assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: S-Caine™ Peel (Skin Numbing Cream) to Treat Pain During Laser-Assisted Tattoo Removal in Adults
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: S-Caine™ Peel (lidocaine and tetracaine cream 7%/7%)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Fairly Brief Androgen Suppression and Stereotactic Radiotherapy for High Risk Prostate Cancer - Protocol 2
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: RADIATION: Radiation|DRUG: Androgen Suppression
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability of Lithium in Spinocerebellar Ataxia 2 (SCA2)
Status: COMPLETED
Conditions: SPINOCEREBELLAR ATAXIA 2
Interventions: DRUG: LITHIUM CARBONATE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Zinc Effect on Inflammation and Cardiovascular Risk in HIV
Status: ACTIVE_NOT_RECRUITING
Conditions: Inflammation|Cardiovascular Diseases|Zinc Deficiency
Interventions: DRUG: Zinc Gluconate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Early Impact of Postoperative Bracing on Pain and Quality of Life Following Posterior Instrumented Fusion for Lumbar Degenerative Conditions
Status: COMPLETED
Conditions: Lumbar Degenerative Conditions
Interventions: OTHER: Brace Group|OTHER: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: MUSE-S Headband System for Improving Anxiety and Insomnia Among Breast Cancer Survivors
Status: RECRUITING
Conditions: Breast Carcinoma
Interventions: OTHER: Electronic Health Record Review|OTHER: Medical Device Usage and Evaluation|PROCEDURE: Meditation Therapy|OTHER: Survey Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Gefitinib Versus Pemetrexed for Previously Treated NSCLC Patients
Status: COMPLETED
Conditions: Previous Treated Metastatic Non-small Cell Lung Cancer
Interventions: DRUG: Gefitinib|DRUG: Pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Elesclomol (STA-4783) With Paclitaxel Versus Paclitaxel Alone in Melanoma
Status: TERMINATED
Conditions: Melanoma
Interventions: DRUG: Elesclomol (STA-4783)|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity of Co-administered Oral Polio Vaccine and Oral Cholera Vaccine
Status: UNKNOWN
Conditions: Vaccine Reaction
Interventions: BIOLOGICAL: Oral Polio Vaccine|BIOLOGICAL: Oral Cholera Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of D-allulose (Psicose) With Sucrose Beverage on Glucose Tolerance and Insulin Level
Status: COMPLETED
Conditions: Impaired Glucose Tolerance
Interventions: DIETARY_SUPPLEMENT: D-allulose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Administration of Itraconazole on the Pharmacokinetics of S-309309 in Healthy Participants
Status: COMPLETED
Conditions: Obesity|Healthy Volunteers
Interventions: DRUG: S309309|DRUG: Itraconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Detection of the Effect of Irrigation Fluid on Extravascular Lung Water in Patients Undergoing TRUP Using Bedside Lung Ultrasound
Status: NOT_YET_RECRUITING
Conditions: TUR Syndrome|Anesthesia
Interventions: PROCEDURE: transurethral resection of the prostate
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Acetazolamide on Right Ventricular Function During Exercise in Patients With Respiratory Disease at Altitude
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: ACETAZOLAMIDE oral capsule|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Comparison of 18g of Tiotropium Inhalation Capsules Once Daily and Atrovent Metered Dose Inhaler (2 Puffs of 20g, 4 Times Daily) in a Double-Blind, Double-Dummy, Efficacy and Safety Study in Adults With Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: tiotropium inhalation powder capsule|DRUG: ipratropium bromide Metered Dose Inhaler
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Topical Perillyl Alcohol in Treating Patients With Sun Damaged Skin and Actinic Keratoses
Status: COMPLETED
Conditions: Precancerous Condition
Interventions: DRUG: perillyl alcohol|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Rapid Screening Test for Detection of Adenovirus in Tears
Status: COMPLETED
Conditions: Acute Conjunctivitis|Adenoviral Conjunctivitis
Interventions: DEVICE: RPS Adeno Detector
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE|Primary Purpose: DIAGNOSTIC
Clinical trial: Risk of Mental Health Conditions in Children and Young Adults With Inflammatory Bowel Disease and Influence on Health
Status: COMPLETED
Conditions: Inflammatory Bowel Diseases|Depressive Episode|Recurrent Depressive Disorder|Anxiety Disorder|Psychological Disorder|Self Harm|Suicide, Attempted|Parasuicide|Eating Disorders|Body Image Disorder|Attention Deficit Hyperactivity Disorder|Behavioral Disorder|Adjustment Disorders|Acute Stress Disorder|Schizophrenia|Bipolar Disorder|Post-traumatic Stress Disorder|Sleep Disturbance
Interventions: OTHER: Exposure of mental health condition
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Egg-derived Influenza Vaccine and Cell Culture-derived Influenza Vaccine in Adult and Elderly Subjects
Status: COMPLETED
Conditions: Influenza, Human
Interventions: BIOLOGICAL: NBP607|BIOLOGICAL: Agrippal S1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Trial on Oral Appliance Design for Improving Upper Airway Function and Sleep Quality
Status: COMPLETED
Conditions: Obstructive Sleep Apnea
Interventions: DEVICE: oral appliance - A ; washout; oral appliance B|DEVICE: oral appliance - B; washout; oral appliance A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reducing Sedentary Time in Obese Adults (Study 2)
Status: WITHDRAWN
Conditions: Obesity
Interventions: BEHAVIORAL: B-MOBILE Smartphone-Based Intervention (3-min break)|BEHAVIORAL: B-MOBILE Smartphone-Based Intervention (6-min break)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trastuzumab Deruxtecan for Subjects With HER2-Positive Gastric Cancer or Gastro-Esophageal Junction Adenocarcinoma After Progression on or After a Trastuzumab-Containing Regimen (DESTINY-Gastric04)
Status: RECRUITING
Conditions: Gastric Cancer, Adenocarcinoma|Gastroesophageal Junction Adenocarcinoma
Interventions: DRUG: Trastuzumab deruxtecan|DRUG: Ramucirumab|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Remediation Program Via a "Serious Game" for the Cognitive Functions of Multiple Sclerosis Patients
Status: RECRUITING
Conditions: Multiple Sclerosis|Memory|Learning
Interventions: DIAGNOSTIC_TEST: Serious game|DIAGNOSTIC_TEST: Usual HAS care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Postprandial Monocyte Maturation and Vascular Dysfunction Following High-Fat Meals - Study 1
Status: COMPLETED
Conditions: Cardiovascular Risk Factor|Lipemia
Interventions: OTHER: High-fat meal
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Bilateral Paravertebral Blockade (T7-10) vs. Incisional Local Anesthetic Administration for Pediatric Patients
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: DRUG: control group|DRUG: treatment group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Human Mesenchymal Stem Cells For Bronchopulmonary Dysplasia
Status: UNKNOWN
Conditions: Bronchopulmonary Dysplasia
Interventions: DRUG: Transplantation of mesenchymal stem cell|DRUG: No transplantation of mesenchymal stem cell
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of Circadian Clock on Hormonal, Metabolic, Neurocognitive Markers in Adolescents With and Without Diabetes
Status: NOT_YET_RECRUITING
Conditions: T1DM|Sleep Disorders, Circadian Rhythm|ADHD|Memory Impairment
Interventions: BEHAVIORAL: Reversed Circadian Rhythm|BEHAVIORAL: Normal Circadian Rhythm
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phase 2 Study of VE303 for Prevention of Recurrent Clostridioides Difficile Infection
Status: COMPLETED
Conditions: Clostridium Difficile Infection Recurrence|Clostridium Difficile Infection|Clostridium Difficile|Clostridioides Difficile Infection Recurrence|Clostridioides Difficile Infection|Clostridioides Difficile|CDI
Interventions: DRUG: VE303|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Does a Nasal Instillation of Vardenafil Normalize the Nasal Potential Difference in Cystic Fibrosis Patients?
Status: TERMINATED
Conditions: Cystic Fibrosis
Interventions: DRUG: Vardenafil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Transversus Abdominis Plane Block and Erector Spinae Plane Block in Inguinal Hernia Repair
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: PROCEDURE: ESP Block|PROCEDURE: TAP Block|OTHER: Standard Pain Followup and Monitorization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of the Efficacy of Scorpion Antivenom Therapy in a Dose-response Manner, in Patients With Scorpionism
Status: RECRUITING
Conditions: Centruroides Envenomation
Interventions: DRUG: Traditional scorpion antivenom regimen|DRUG: Serial dose of scorpion antivenom regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Holmium Ho 166 DOTMP Followed by Peripheral Stem Cell Transplantation in Treating Patients With Metastatic Ewing's Sarcoma or Rhabdomyosarcoma That Has Spread to the Bone
Status: COMPLETED
Conditions: Metastatic Cancer|Sarcoma
Interventions: PROCEDURE: peripheral blood stem cell transplantation|RADIATION: holmium Ho 166 DOTMP
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Safety, Efficacy and Immunogenicity of Leishmania Vaccine ChAd63-KH in PKDL
Status: COMPLETED
Conditions: Leishmaniasis, Cutaneous
Interventions: BIOLOGICAL: ChAd63-KH|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Benefit of Early Treatment With an Endothelin Inhibitor (Bosentan) in Patients With Sudden Blindness Due to Giant Cell Arteritis: CECIBO
Status: UNKNOWN
Conditions: Arteritis, Giant Cell|Blindness and Low Vision
Interventions: DRUG: treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PROFILe3: Epidemiologic Survey in Patients With Schizophrenia or Schizoaffective Disorders
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder|Schizophreniform Disorder
Interventions: DRUG: antipsychotic medications
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Can Iron Lessen Anemia Due to Cancer and Chemotherapy: A Study to Investigate the Efficacy and Safety of Injectafer®
Status: COMPLETED
Conditions: Cancer and Chemotherapy Related Anemia
Interventions: DRUG: Injectafer|OTHER: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Study of Two Forms of Topical Dexchlorpheniramine Maleate (Cream Versus Gel) for Insect Bites
Status: UNKNOWN
Conditions: Insect Bites
Interventions: DRUG: Dexchlorpheniramine 1% Gel|DRUG: Dexchlorpheniramine 1% Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Evaluation of Cognitive Outcomes After Anesthesia on Patients in the Beach Chair Position
Status: COMPLETED
Conditions: Injury as a Result of Positioning
Interventions: DEVICE: NIRS|DEVICE: NIRS monitored not treated
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Open-label Study of Asciminib for CML-CP or CML-AP Patients With T315I Mutation Who Are Resistant, Intolerant or Ineligible to Ponatinib.
Status: NOT_YET_RECRUITING
Conditions: Chronic Myeloid Leukemia (CML)
Interventions: DRUG: ABL001/Asciminib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Compare the Operating Condition of Two Levels of Muscle Relaxation on Facial Nerve MEP Monitoring in CPA Surgery
Status: COMPLETED
Conditions: Cerebellopontine Angle Tumor
Interventions: DRUG: Rocroniom, Non Depolarizing Muscle Relaxant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SCREENING
Clinical trial: Ubiquinol Treatment in Patients With Heart Failure and Preserved Ejection Fraction
Status: UNKNOWN
Conditions: Heart Failure
Interventions: DRUG: ubiquinol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Centralized Lung Cancer EARly Detection Among Smokers (CLEAR Study)
Status: RECRUITING
Conditions: Smoking|Lung Cancer
Interventions: OTHER: Best Practice|DRUG: Nicotine Patch|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration|OTHER: Tobacco Cessation Counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Evaluation of Effectiveness of Two Different Doses of Mivacurium in Rapid Sequence Intubation
Status: RECRUITING
Conditions: Emergencies
Interventions: DRUG: "Mivacurium Chloride"
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Open-label, Long-term Safety Study of LP352 in Subjects With Developmental and Epileptic Encephalopathy
Status: ACTIVE_NOT_RECRUITING
Conditions: Developmental and Epileptic Encephalopathy|Dravet Syndrome|Lennox-Gastaut Syndrome
Interventions: DRUG: LP352, bexicaserin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Arnica and the Management of Pain in Acute Musculoskeletal Extremity Injuries
Status: UNKNOWN
Conditions: Pain, Muscle|Pain, Acute
Interventions: DRUG: Arnica|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Relapse-prevention Study With Lu AA21004 (Vortioxetine) in Patients With Generalized Anxiety Disorder
Status: COMPLETED
Conditions: Generalized Anxiety Disorder
Interventions: DRUG: Lu AA21004|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Keyhole Limpet Hemocyanin Compared With Doxorubicin in Treating Patients With Bladder Cancer
Status: COMPLETED
Conditions: Bladder Cancer
Interventions: BIOLOGICAL: keyhole limpet hemocyanin|DRUG: doxorubicin hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Bioavailability and Biological Effects of Vitamin D2 Contained in Mushroom
Status: COMPLETED
Conditions: Vitamin D Deficiency|Metabolic Syndrome|Prediabetes
Interventions: DIETARY_SUPPLEMENT: Mushroom with 600 IU vitamin D2|DIETARY_SUPPLEMENT: Mushroom with 4000 IU Vitamin D2|DIETARY_SUPPLEMENT: 600 IU Vitamin D3 and untreated mushroom|DIETARY_SUPPLEMENT: 4000 IU Vitamin D3 and untreated mushroom|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vaccination Study of Abatacept (BMS-188667) for Normal Healthy Volunteers
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Tetanus + pnemococcal vaccines alone|DRUG: Abatacept + vaccines|DRUG: Abatacept + vaccines|DRUG: Abatacept + Vaccines
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of E-Cigarettes in Menthol Smokers
Status: COMPLETED
Conditions: E-cigarette Use|Smoking Behaviors
Interventions: DEVICE: JUUL E-Cigarette Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Genetic Variates of Response to Cisplatin, Vinblastine, and Temozolomide (CVT) in Patients With Metastatic Melanoma
Status: COMPLETED
Conditions: Melanoma|Skin Cancer
Interventions: DRUG: Cisplatin, Vinblastine, Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anti-Inflammatory and Anti-Fibrotic Drugs in Post COVID-19 Pulmonary Fibrosis
Status: COMPLETED
Conditions: Post-COVID-19 Syndrome|Lung Fibrosis
Interventions: DRUG: Corticosteroids alone|DRUG: Corticosteroids + Colchicine|DRUG: Corticosteroids + Pirfenidone|DRUG: Corticosteroids + Colchicine + Pirfenidone for ≥ 14 days
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Motivational Interviews for Depression in Primary Care
Status: COMPLETED
Conditions: Major Depression
Interventions: BEHAVIORAL: Guideline-Based Medical Management|BEHAVIORAL: Motivational Interviewing for Depression
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Assessing Patient Response to Therapeutic Exercise Based on Clinical Prediction Rule (CPR) for Spinal Manipulation
Status: COMPLETED
Conditions: Low Back Pain
Interventions: PROCEDURE: MDT (McKenzie Method)|PROCEDURE: Spinal thrust manipulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intensive Statin Therapy Effect on Post-Operative Atrial Fibrillation (POAF)
Status: UNKNOWN
Conditions: Cardiothoracic Surgery|Post-operative Atrial Fibrillation
Interventions: DRUG: Atorvastatin 20 mg|DRUG: Atorvastatin 80 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Treatment Satisfaction and Preference for Sumavel DosePro in the Treatment of Migraine
Status: COMPLETED
Conditions: Migraine
Interventions: DEVICE: Sumavel DosePro|DRUG: Sumatriptan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: What is the Best Preparation for Embryo Transfer in Cryo Cycles: a Natural Cycle or Light Hormonal Stimulation?
Status: UNKNOWN
Conditions: Infertility
Interventions: DRUG: human menopausal gonadotrophins
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CARS: Cannabis and Alcohol Reduction Study
Status: RECRUITING
Conditions: Cannabis Use|Alcohol Use, Unspecified|Substance Use|Substance Use Disorders
Interventions: BEHAVIORAL: modified Approach-Avoidance Task (mAAT), which aims to modify automatic approach bias|BEHAVIORAL: modified Approach-Avoidance Task (mAAT) that does not aim to modify automatic approach bias.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of MEDI7352 in Subjects With Painful Diabetic Neuropathy
Status: COMPLETED
Conditions: Painful Diabetic Neuropathy
Interventions: BIOLOGICAL: MEDI7352|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Tolerance, Suckling and Food Intake After Repeated Nasals Administrations of Oxytocin in PWS Infants
Status: COMPLETED
Conditions: Prader Willi Syndrome
Interventions: DRUG: oxytocin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of GS-1427 in Participants With Moderately to Severely Active Ulcerative Colitis
Status: RECRUITING
Conditions: Ulcerative Colitis
Interventions: DRUG: GS-1427|DRUG: Ustekinumab|DRUG: Placebo-to-match GS-1427
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Maraviroc in Rheumatoid Arthritis
Status: TERMINATED
Conditions: Arthritis, Rheumatoid
Interventions: DRUG: Maraviroc|DRUG: Maraviroc Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Difluprednate vs. Prednisolone Acetate on Visual Acuity, and Corneal Edema Following Cataract Surgery.
Status: COMPLETED
Conditions: Cataracts|Corneal Edema|Retinal Structural Change, Deposit and Degeneration|Visual Acuity Reduced Transiently
Interventions: DRUG: Difluprednate ophthalmic emulsion 0.05%|DRUG: Prednisolone acetate 1%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Combination of Mosapride and DPP-4 Inhibitor on Plasma Concentration of Incretin Hormones
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Mosapride citrate|DRUG: Linagliptin|DRUG: Acetaminophen (paracetamol)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Phase I/II Trial of Letrozole and Sorafenib in Post-Menopausal Hormone-Receptor + Breast Cancer
Status: COMPLETED
Conditions: Metastatic Breast Cancer
Interventions: DRUG: Sorafenib|DRUG: Letrozole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cardiac Safety and Efficacy for Early-stage Breast Cancer Patients Treated With Pegylated Liposomal Doxorubicin（PLD)
Status: UNKNOWN
Conditions: Early Breast Cancer
Interventions: DRUG: PLD|DRUG: CTX|DRUG: Docetaxel|DRUG: Paclitaxel|DRUG: Doxorubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hydrocodone Compared to Acetaminophen and Ibuprofen for Post-nail Procedure Analgesia
Status: COMPLETED
Conditions: Nail Diseases|Nail Abnormality
Interventions: DRUG: Hydrocodone 5Mg/Acetaminophen 325Mg Tab|DRUG: Acetaminophen 1000mg|DRUG: Ibuprofen 400 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimizing Feedback-based Learning in Children With Developmental Language Disorder
Status: RECRUITING
Conditions: Developmental Language Disorder
Interventions: BEHAVIORAL: Declarative learning with immediate feedback|BEHAVIORAL: Declarative learning with delayed feedback|BEHAVIORAL: Probabilistic learning with immediate feedback|BEHAVIORAL: Probabilistic learning with delayed feedback|BEHAVIORAL: Word learning task with active feedback|BEHAVIORAL: Word learning task with passive feedback
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Nonpharmacologic Pain Management in FQHC Primary Care Clinics
Status: RECRUITING
Conditions: Low Back Pain|Chronic Pain
Interventions: BEHAVIORAL: Brief Pain Teleconsult|BEHAVIORAL: Telehealth Physical Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Effects on Blood Pressure and Pulse Rate of a Single 100mg Dose of Sildenafil in Patients With Benign Prostatic Hyperplasia Who Are Being Treated With Doxazosin
Status: COMPLETED
Conditions: Benign Prostatic Hyperplasia
Interventions: DRUG: placebo|DRUG: sildenafil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Donor Peripheral Stem Cell Transplant in Treating Patients With Myelodysplastic Syndrome, Acute Myeloid Leukemia, or Myeloproliferative Disorder
Status: COMPLETED
Conditions: Chronic Myeloproliferative Disorders|Leukemia|Myelodysplastic Syndromes|Myelodysplastic/Myeloproliferative Diseases
Interventions: DRUG: busulfan|DRUG: cyclophosphamide|DRUG: cyclosporine|DRUG: methotrexate|PROCEDURE: in vitro-treated peripheral blood stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Iressa Re-Challenge in Advanced NSCLC EGFR M+ Patients Who Responded to Gefitinib USed as 1st Line or Previous Treatment
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DRUG: Gefitinib 250mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose-Escalation Study of Oral Administration of LP-108 as Monotherapy and in Combination With Azacitidine in Patients With Relapsed or Refractory MDS, CMML, or AML
Status: ACTIVE_NOT_RECRUITING
Conditions: AML/MDS|CMML|Relapse|Refractory Acute Lymphoblastic Leukemia|Relapse Leukemia|Relapsed Adult AML
Interventions: DRUG: LP-108|DRUG: LP-108 and azacitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Milk Thistle in Pathological Gambling
Status: COMPLETED
Conditions: Pathological Gambling|Gambling Disorder
Interventions: DRUG: Placebo|DRUG: Milk Thistle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Oral Steroids in Chronic Rhinosinusitis Without Nasal Polyps
Status: COMPLETED
Conditions: Sinusitis
Interventions: DRUG: 6 day Prednisone|DRUG: Augmentin|DRUG: 21 day Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study of Chinese Herbal Compound TJAOA101 in the Treatment of Premature Ovarian Insufficiency
Status: NOT_YET_RECRUITING
Conditions: Premature Ovarian Failure
Interventions: DRUG: TJAOA101
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Autologous Bone Marrow Stem Cells for Chronic Leg Ulcer Treatment in Sickle Cell Disease
Status: UNKNOWN
Conditions: Chronic Leg Ulcer|Sickle Cell Disease
Interventions: BIOLOGICAL: Infusion of Autologous Bone Marrow Mononuclear Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: REduced Pain After Bariatric Surgery - Sleeve Gastrectomy
Status: COMPLETED
Conditions: Pain|Postoperative Pain|Acute Pain|Analgesia|Bariatric Surgery Candidate|Anesthesia
Interventions: PROCEDURE: LG-TAP block with local anesthetic|PROCEDURE: LG-TAP block with saline solution|PROCEDURE: Port site infiltration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Study to Evaluate Immune Response of Vaccines in Participants With Relapsing Forms of Multiple Sclerosis Who Receive Ozanimod Compared to Non-Pegylated Interferon (IFN)-β or No Disease Modifying Therapy
Status: COMPLETED
Conditions: Multiple Sclerosis|Multiple Sclerosis, Relapsing-Remitting
Interventions: BIOLOGICAL: Tetanus, diphtheria, and acellular pertussis vaccine|BIOLOGICAL: Pneumococcal polysaccharide vaccine|BIOLOGICAL: Seasonal influenza vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Ibandronate (Boniva) to Evaluate Bone Turnover Markers in Women With Treatment-Naive Postmenopausal Osteoporosis
Status: COMPLETED
Conditions: Post Menopausal Osteoporosis
Interventions: DRUG: Ibandronate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomised, Open-label Trial to Assess the Safety and Efficacy of Switching to Tenofovir-emtricitabine or Abacavir-lamivudine: The STEAL Study
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Emtricitabine 200mg - Tenofovir 300mg|DRUG: Abacavir 600mg - Lamivudine 300mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Verification of Correlation Between Genetic Testing of Nutritional Metabolism and Clinical Biochemical Indicators
Status: UNKNOWN
Conditions: Pregnant Women
Interventions: DIETARY_SUPPLEMENT: Normal iron|DIETARY_SUPPLEMENT: Weak iron|DIETARY_SUPPLEMENT: Normal selenium|DIETARY_SUPPLEMENT: Weak selenium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: AFT/CLP-LAL RCT Stage 3 or 4 Pressure Injuries
Status: COMPLETED
Conditions: Pressure Ulcer
Interventions: DEVICE: Air Fluidized Therapy|DEVICE: Continuous Low Pressure-LAL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multicenter Randomized Double-blind Placebo-controlled Study to Investigate Azvudine in Symptomatic Adults With COVID-19 at Increased Risk of Progressing to Severe Illness
Status: NOT_YET_RECRUITING
Conditions: COVID-19 Respiratory Infection
Interventions: DRUG: Azvudine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I Dose Escalation Study of Oral SB939 Administered Alone or With Azacitidine
Status: COMPLETED
Conditions: Solid Tumors|Hematologic Malignancies|Myelodysplastic Syndrome
Interventions: DRUG: SB939|DRUG: Azacitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transcranial Magnetic Stimulation in Smokers: an Examination of Mediating Neural Pathways.
Status: COMPLETED
Conditions: Smoking
Interventions: DEVICE: Active repetitive Transcranial Magnetic Stimulation|DEVICE: Sham repetitive Transcranial Magnetic Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Reslizumab to Treat Eosinophilic Esophagitis in Subjects Aged 5 to 18 Years
Status: COMPLETED
Conditions: Eosinophilic Esophagitis
Interventions: BIOLOGICAL: Reslizumab|OTHER: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Enjoy Your Bump : Online Cognitive Behavioural Therapy in Pregnancy
Status: COMPLETED
Conditions: Perinatal Mental Health|Antenatal Depression|Antenatal Anxiety
Interventions: DEVICE: Enjoy Your Bump
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Immune Ablation and Hematopoietic Stem Cell Support in Patients With Systemic Lupus Erythematosus: A Phase II Study
Status: COMPLETED
Conditions: Systemic Lupus Erythematosus
Interventions: BIOLOGICAL: Immune ablation and hematopoietic stem cell support.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open-label Study to Assess Immunogenicity and Safety of a Vaccine Enhancement Patch When Administered With 2 Doses of H5N1 Vaccine
Status: COMPLETED
Conditions: Healthy
Interventions: BIOLOGICAL: A/H5N1 Antigen|DRUG: Vaccine Enhancement Patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Vitamin K2 n Human Osteoporosis, Blood-vessel Calcification and Sclerosis
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Vit K2+ Vit D3+ calcium carbonate (CaCO3)|DIETARY_SUPPLEMENT: Vit K2+CaCO3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Vigil™ + Nivolumab in Advanced Non-Small Cell Lung Cancer
Status: WITHDRAWN
Conditions: Advanced Non-small Cell Lung Cancer|Metastatic Non-small Cell Lung Cancer|Lung Neoplasms
Interventions: BIOLOGICAL: Vigil™|DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Pre-defined, Fixed Dose of Gonal-f Pen Based on Subject Baseline Characteristics in Subjects Undergoing in Vitro Fertilization (IVF)
Status: COMPLETED
Conditions: Infertility
Interventions: DRUG: Gonal-f|DRUG: Recombinant human chorionic gonadotrophin (r-hCG)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Increasing Doses of Combretastatin in Combination With Bevacizumab (Avastin) in Patients With Advanced Solid Tumors
Status: COMPLETED
Conditions: Tumors
Interventions: DRUG: Combretastatin A4 Phosphate (CA4P)|DRUG: Bevacizumab (Avastin)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Protective Potential of Exercise Training on the Cardiopulmonary Morbidity After COVID-19
Status: COMPLETED
Conditions: COVID-19, SARS-CoV2
Interventions: BEHAVIORAL: High intensity interval training|BEHAVIORAL: Standard care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study to Evaluate the Pharmacokinetics of Avacopan (CCX168) in Participants With Mild or Moderate Hepatic Impairment
Status: COMPLETED
Conditions: Hepatic Impairment
Interventions: DRUG: Avacopan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Tucatinib and Doxil in Participants With Human Epidermal Growth Factor Receptor 2 Positive (HER2+) Metastatic Breast Cancer
Status: RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Tucatinib|DRUG: Doxil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Healthy Homes Study
Status: RECRUITING
Conditions: Home Air Radon Testing|Lung Cancer
Interventions: BEHAVIORAL: Public health infographic (AIM 3)|BEHAVIORAL: Online health promotion intervention tailored by smoking status (AIM 3)|BEHAVIORAL: Online health promotion intervention tailored by smoking status, plus reminder messages (AIM 3)|BEHAVIORAL: Focus group with educational overview (AIM 1)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Binimetinib and Palbociclib Before Surgery for the Treatment of Operable KRAS-Positive Lung, Colorectal, or Pancreatic Cancer
Status: WITHDRAWN
Conditions: Colorectal Carcinoma|Lung Adenocarcinoma|Malignant Solid Neoplasm|Pancreatic Carcinoma
Interventions: DRUG: Binimetinib|DRUG: Palbociclib|PROCEDURE: Therapeutic Conventional Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Bridging Study to Assess the New Formulation of ETVAX
Status: COMPLETED
Conditions: Healty Volunteers|Preventable Disease, Vaccine
Interventions: BIOLOGICAL: Etvax|BIOLOGICAL: Etvax
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Nasal Inhalation of Dornase Alfa (Pulmozyme) in Patients With Cystic Fibrosis and Chronic Rhinosinusitis
Status: COMPLETED
Conditions: Cystic Fibrosis|Chronic Rhinosinusitis
Interventions: DRUG: Pulmozyme
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cefepime-taniborbactam vs Meropenem in Adults With VABP or Ventilated HABP
Status: NOT_YET_RECRUITING
Conditions: Ventilator-associated Pneumonia|Hospital-acquired Pneumonia
Interventions: DRUG: Cefepime-taniborbactam|DRUG: Meropenem
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Children Immune Functions
Status: COMPLETED
Conditions: Diarrhea|Upper Respiratory Infections
Interventions: DIETARY_SUPPLEMENT: heat-treated lactobacilli or placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study Evaluating Combination of Levonorgestrel (LNG) and Ethinyl Estradiol (EE) in Premenstrual Dysphoric Disorder
Status: COMPLETED
Conditions: Menstruation Disturbances|Premenstrual Syndrome
Interventions: DRUG: levonorgestrel/ethinyl estradiol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Refined Nursing in Rehabilitation Training
Status: COMPLETED
Conditions: Brain Injuries
Interventions: BEHAVIORAL: Establishment of a hierarchical monitoring and management team|BEHAVIORAL: Assessment of pressure injury|BEHAVIORAL: Communication|BEHAVIORAL: Intervention for pressure ulcer|BEHAVIORAL: Rehabilitation training|BEHAVIORAL: introduction of the current patient's condition to family members|BEHAVIORAL: maintaining appropriate temperature and humidity in the ward|BEHAVIORAL: careful observation of vital signs in patients
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Cryolipolysis Versus ATX-101 (Deoxycholic Acid) for Upper Back Fat
Status: ACTIVE_NOT_RECRUITING
Conditions: Upper Back Fat
Interventions: DEVICE: CoolCurve|DRUG: ATX-101
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Antibiotic Resistance and Microbiome in Children Aged 6-59 Months in Nouna, Burkina Faso
Status: COMPLETED
Conditions: Child Development
Interventions: DRUG: Azithromycin|DRUG: Amoxicillin|DRUG: Cotrimoxazole|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Addition of Ondansetron to Ongoing Antipsychotic Treatment for Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Ondansetron followed by placebo|DRUG: Placebo followed by Ondansetron
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacological Intervention in Diabetic Retinopathy
Status: COMPLETED
Conditions: Diabetic Retinopathy
Interventions: DRUG: Latanoprost, diclofenac and dorzolamide (eyedrops)|DRUG: Diclofenac|DRUG: Dorzolamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Changes in Serum, Follicular Fluid SREBP1c and LRG1 Levels in PCOS Patients and Correlation With Insulin Resistance
Status: RECRUITING
Conditions: PCOS (Polycystic Ovary Syndrome) of Bilateral Ovaries
Interventions: DIAGNOSTIC_TEST: HOMA-IR，ESHRE/ASRM
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Functional Improvement of Progenitor Cells and Endothelial Function by Vildagliptin in Diabetes Mellitus (FINNjA-DM).
Status: WITHDRAWN
Conditions: SDF-1 is an Important Cytokine for Neovascularization. Cleavage of SDF-1 is Reduced by DPPIV Inhibitors
Interventions: DRUG: Vildagliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of a Prototype for an Innovative Room for the Elderly
Status: NOT_YET_RECRUITING
Conditions: Elderly Inpatients
Interventions: BEHAVIORAL: Hospi'Senior|BEHAVIORAL: Conventional room
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pharmacokinetic Characterization of Two Novel CG5503 Tablet Formulations in Healthy Volunteers
Status: COMPLETED
Conditions: Pharmacokinetics
Interventions: DRUG: Tapentadol Test Product 1|DRUG: Tapentadol Test Product 2|DRUG: Tapentadol Prolonged-release Reference Product
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT