pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Combination of Curcuminoid With Acupressure for Inflammation and Pain in the Elderly With Osteoarthritis Genu
Status: ENROLLING_BY_INVITATION
Conditions: Osteoarthritis, Knee
Interventions: PROCEDURE: Acupressure and Standardized Curcuminoid from Turmeric Extract|PROCEDURE: Sham Acupressure and Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Kinesio Taping in the Treatment of Nonspecific Acute Low Back Pain
Status: COMPLETED
Conditions: Back Pain
Interventions: PROCEDURE: Kinesio Taping|PROCEDURE: Traditional Physical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility Study of Ultrasound-guided Functional Remodeling of Lower Extremity Superficial Venous Valve
Status: RECRUITING
Conditions: Varicose Veins of Lower Limb
Interventions: PROCEDURE: Ultrasound guided functional remodeling of lower extremity superficial vein valve
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Skin Surface's Temperature Changes When Auricular Acupressure at Cervical Vertebra Acupoints in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: PROCEDURE: Auricular acupressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Lenalidomide, Dexamethasone and MEDI-551 in Untreated Multiple Myeloma
Status: COMPLETED
Conditions: Myeloma
Interventions: DRUG: Lenalidomide, Dexamethasone, and MEDI-551
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Retrospective Observational Study to Evaluate the Utilization, Outcomes, and Adverse Events in Participants Treated With Minocin® (Minocycline) for Infections Caused by Gram-negative Bacteria in a Real World Setting
Status: COMPLETED
Conditions: Gram-Negative Bacterial Infections
Interventions: DRUG: Minocycline IV
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Safety and Efficacy of Albis®: The Prevention of Aspirin-induced Gastrointestinal Ulcers in Patients
Status: UNKNOWN
Conditions: Patients Taking Low-dose Aspirin
Interventions: DRUG: Albis Tab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Rapid Evaluation of Pandemic H1N1 Influenza Vaccine in Adults With HIV
Status: COMPLETED
Conditions: HIV Infections|H1N1 Influenza
Interventions: BIOLOGICAL: Arepanrix|BIOLOGICAL: Arepanrix
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Using a Tailored Health Information Technology Driven Intervention to Improve Health Literacy and Medication Adherence
Status: COMPLETED
Conditions: Vascular Disease|Cerebrovascular Disorders|Ischemic Heart Disease|Coronary Artery Disease
Interventions: BEHAVIORAL: Talking Rx
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Effect of Instrument Assisted Soft Tissue Mobilization in Adhesive Capsulıtıs Treatment
Status: COMPLETED
Conditions: Adhesive Capsulitis|ınstrument assısted Soft tıssue molılızatıon
Interventions: DEVICE: soft tissue mobilization|OTHER: conventional physical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: CRP-guided Antibiotic Treatment in COPD Exacerbations Admitted to the Hospital
Status: UNKNOWN
Conditions: COPD|Exacerbation|Bronchitis|Sputum|C-Reactive Protein
Interventions: OTHER: CRP-guided antibiotic treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Observational, Multi-Center Study of the Real World Evidence of the Effectiveness of Paritaprevir/r - Ombitasvir, ± Dasabuvir, ± Ribavirin in Patients With Chronic Hepatitis C in the Russian Federation
Status: COMPLETED
Conditions: Chronic Hepatitis C|Genotype 1
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: ACY-1215 (Ricolinostat) in Combination With Pomalidomide and Low-dose Dex in Relapsed-and-Refractory Multiple Myeloma
Status: TERMINATED
Conditions: Multiple Myeloma
Interventions: DRUG: ACY-1215 (Ricolinostat) in combination with pomalidomide and dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I/II Study of ABI-007 (Abraxane®, Nab®-Paclitaxel)and Vinorelbine in Patients With Stage IV (Metastatic) Breast Cancer
Status: TERMINATED
Conditions: Stage IV (Metastatic) Breast Cancer
Interventions: DRUG: ABI-007|DRUG: vinorelbine|DRUG: Trastuzumab|BIOLOGICAL: G-CSF
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety of an Inactivated Split-virion 2009 Pandemic Influenza A H1N1 Vaccine in Infants
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: split-virion, non-adjuvanted vaccine of 7.5 μg|BIOLOGICAL: split-virion, non-adjuvanted H1N1 vaccine of 15 μg|BIOLOGICAL: split-virion, non-adjuvanted vaccine of seasonal influenza
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Escalating Multiple-Dose Safety and Tolerance of WR 6026 Hydrochloride in HIV-Infected Subjects
Status: COMPLETED
Conditions: Pneumonia, Pneumocystis Carinii|HIV Infections
Interventions: DRUG: Sitamaquine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Impact of Cervical Lordosis Rehabilitation on Autonomic Nervous Function and Cervical Sensorimotor Control
Status: UNKNOWN
Conditions: Chronic Nonspecific Neck Pain
Interventions: OTHER: Sagittal Cervical Posture Corrective Orthotic Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ibudilast for Treating Alcohol Use Disorder
Status: RECRUITING
Conditions: Alcohol Use Disorder (AUD)|Alcoholism
Interventions: DRUG: Ibudilast|BEHAVIORAL: Medical management|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Toxin Treatment for Amyotrophic Lateral Sclerosis (ALS) Related Sialorrhea
Status: COMPLETED
Conditions: Sialorrhea|Amyotrophic Lateral Sclerosis
Interventions: DRUG: Botox injection|DRUG: Placebo injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Stopping Benzodiazepines and Related Molecules Among Elderly Living in Residential Institutions
Status: COMPLETED
Conditions: Elderly|Drug Therapy Syndrome|Substance-Related Disorders|Substance Withdrawal Syndrome
Interventions: DRUG: Immediate intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Longitudinal Observational Biomarker Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Depression|Dementia|Mild Cognitive Impairment
Interventions: BEHAVIORAL: Mechanisms of Late life depression (LLD)-dementia through functional Magnetic Resonance Imaging (fMRI)|BEHAVIORAL: Neuropsychological Data|BEHAVIORAL: Clinical Scales
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Treatment of Cutaneous Leishmaniasis With Liposomal Amphotericin B in the Elderly
Status: COMPLETED
Conditions: Cutaneous Leishmaniasis, American
Interventions: DRUG: Liposomal amphotericin B (AmBisome®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Opioid Dispenser for Microdiscectomy/Laminectomy
Status: NOT_YET_RECRUITING
Conditions: Opioid Use|Pain, Postoperative|Medical Device|Laminectomy|Diskectomy
Interventions: DEVICE: Opioid-Dispensing Device|OTHER: App|OTHER: Standard Opioid Pill Bottle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Lymphatic Mapping and Sentinel Lymph Node Biopsy in the Treatment of Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: PROCEDURE: Preoperative Endoscopy|RADIATION: Technetium Tc 99m Sulfur Colloid|PROCEDURE: Gamma Probe|PROCEDURE: Biopsy of Sentinel Lymph Nodes
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Comparison of Atovaquone and Pentamidine in the Prevention of Pneumocystis Carinii Pneumonia in HIV-Infected Patients Who Cannot Take TMP/SMX
Status: COMPLETED
Conditions: Pneumonia, Pneumocystis Carinii|HIV Infections
Interventions: DRUG: Atovaquone|DRUG: Pentamidine isethionate
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Oxaliplatin and Liposomal Irinotecan (Plus Trastuzumab for HER2-positive Disease) in Advanced Esophageal and Gastric Adenocarcinoma
Status: RECRUITING
Conditions: Esophageal Adenocarcinoma|Gastric Adenocarcinoma
Interventions: DRUG: Nal-IRI|DRUG: Oxaliplatin|DRUG: 5-FU|DRUG: Trastuzumab|DRUG: Pembrolizumab|DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nutritional Treatment for the Amelioration of Traumatic Brain Injury
Status: ACTIVE_NOT_RECRUITING
Conditions: Traumatic Brain Injury
Interventions: DIETARY_SUPPLEMENT: Souvenaid oral nutritional supplement (Nutricia)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination of Ibrutinib and As2O3 in the Treatment of CLL
Status: UNKNOWN
Conditions: Leukemia, Lymphocytic, Chronic, B-Cell
Interventions: DRUG: Ibrutinib combined with As2O3|DRUG: ibrutinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: STereotactic Ablative Radiosurgery of Recurrent Ventricular Tachycardia in Structural Heart Disease
Status: RECRUITING
Conditions: Ventricular Tachycardia
Interventions: PROCEDURE: Radiosurgery|PROCEDURE: Repeated catheter ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Bruton's Tyrosine Kinase Inhibitor Ibrutinib Given in Combination With Bendamustine and Rituximab in Patients With Newly Diagnosed Mantle Cell Lymphoma
Status: COMPLETED
Conditions: Mantle Cell Lymphoma
Interventions: DRUG: Bendamustine|DRUG: Rituximab|DRUG: Ibrutinib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Electromyographic and Acceleromyographic Monitoring in Restricted Arm Movement Surgical Setting
Status: COMPLETED
Conditions: Residual Neuromuscular Blockade
Interventions: DEVICE: Tetragraph|DEVICE: ToFscan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Molecular Risk Assessment in Planning Treatment for Patients With Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: BIOLOGICAL: rituximab|DRUG: cyclophosphamide|DRUG: doxorubicin hydrochloride|DRUG: prednisone|DRUG: vincristine sulfate|GENETIC: microarray analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preloading to Prevent Hypotension During Cesarean Section
Status: COMPLETED
Conditions: Obstetric Anesthesia Problems
Interventions: DRUG: Fluid therapy|PROCEDURE: Spinal anaesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Clinical Examination of Metal Free Interdental Brushes
Status: COMPLETED
Conditions: Gingivitis|Periodontitis
Interventions: DEVICE: metal-free interdental brush|DEVICE: metal-core interdental brush
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: StratCare Trial 2: Evaluating the Clinical and Cost-effectiveness of AI-driven Stratified Care for Depression
Status: NOT_YET_RECRUITING
Conditions: Depression
Interventions: DEVICE: Stratcare
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Evaluation of Optimal Dose of Local Anesthetics for Patient Controlled Continuous Femoral Nerve Block
Status: UNKNOWN
Conditions: Arthropathy of Knee Joint
Interventions: PROCEDURE: PC-FNB with basal administration of local anesthetics|PROCEDURE: PC-FNB without basal local anesthetics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Observational Study Of A Protease Inhibitor (PI) Containing Regimen In Subjects With PI Mutations Selected During Prior Treatment With GW433908 (Fosamprenavir)
Status: COMPLETED
Conditions: Infection, Human Immunodeficiency Virus I|HIV Infection
Interventions: DRUG: No intervention; Observational study
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose:
Clinical trial: Effects of Exercise and Relaxation Techniques on Tension Headache Pain Parameters of University Students
Status: COMPLETED
Conditions: Tension-Type Headache
Interventions: BEHAVIORAL: Relaxation technique Autogenic Training|BEHAVIORAL: Combined treatment Autogenic Training + Cervical exercises and postural correction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Indocyanine Green for Central Nervous System Tumors
Status: COMPLETED
Conditions: Suspected Central Nervous System Tumors
Interventions: DRUG: Indocyanine Green (ICG)|RADIATION: Intraoperative near-infrared (NIR)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Food and Salt Handling in Diuresis
Status: COMPLETED
Conditions: Nocturia|Polyuria
Interventions: DIAGNOSTIC_TEST: Blood sample|DIAGNOSTIC_TEST: Bio-impedance measurement (BIA)|DIETARY_SUPPLEMENT: Ingestion of testing nutrient/food capsules|DIAGNOSTIC_TEST: Urine sample
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Tiotropium/Salmeterol Inhalation Powder (Spiriva Handihaler and Salmeterol Polyethylene (PE) Capsule) in Chronic Obstructive Pulmonary Disease (COPD)
Status: TERMINATED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Tiotropium/Salmeterol QD|DRUG: Placebo|DRUG: Salmeterol|DRUG: Tiotropium/Salmeterol QD+ Salmeterol|DRUG: Tiotropium (Spiriva®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Intestinal Glucagon-like Peptide-1 (GLP-1) and the Physiological Role in Eating in Humans
Status: COMPLETED
Conditions: Appetite and General Nutritional Disorders
Interventions: DIETARY_SUPPLEMENT: Saline|DRUG: Exendin 9-39|DIETARY_SUPPLEMENT: Saline|DRUG: Exendin(9-39) plus ID nutrient
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study on the Long Term Survivals in an Expand Access Program (EAP) of Iressa
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer
Interventions: GENETIC: EGFR Mutation Test|GENETIC: Ki-67 protein expression
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study on the Construction and Application of Breastfeeding Behavior Intervention Program for Mothers of Infants With Congenital Heart Disease
Status: COMPLETED
Conditions: Heart Defects, Congenital|Breast Feeding
Interventions: OTHER: Conventional care|BEHAVIORAL: Breastfeeding behavioural intervention for mothers of infants with CHD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Testing AZD4547 as a Potential Targeted Treatment in Cancers With FGFR Genetic Changes (MATCH-Subprotocol W)
Status: COMPLETED
Conditions: Advanced Lymphoma|Advanced Malignant Solid Neoplasm|Hematopoietic and Lymphoid Cell Neoplasm|Refractory Lymphoma|Refractory Malignant Solid Neoplasm|Refractory Plasma Cell Myeloma
Interventions: DRUG: FGFR Inhibitor AZD4547
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Validation of an Index of Neutropenia (D-index) in Febrile Neutropenic Cancer Patients
Status: TERMINATED
Conditions: Invasive Fungal Infections|Invasive Aspergillosis|Invasive Fusariosis
Interventions: DRUG: caspofungin as preemptive antifungal therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low Dose Naltrexone for Treatment of Pain in Patients With Fibromyalgia - Effect Via a Central Mechanism?
Status: COMPLETED
Conditions: Fibromyalgia
Interventions: DRUG: Low dose naltrexone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Non-invasive Nerve Stimulation for PTSD and Sleep
Status: RECRUITING
Conditions: Post Traumatic Stress Disorder|Traumatic Brain Injury
Interventions: OTHER: Transcutaneous nerve stimulation location 1|OTHER: Transcutaneous nerve stimulation location 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Crossover Study in the Treatment of Patients With COPD
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Formoterol Fumurate inhalation solution 20 mcg|DRUG: Ipratropium bromide 18 mcg and albuterol sulfate 103 mcg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SB-681323 IV for Subjects at Risk of Acute Lung Injury or ARDS
Status: COMPLETED
Conditions: Lung Injury, Acute
Interventions: DRUG: SB-681323 Intravenous 3mg|DRUG: SB-681323 Intravenous 7.5 mg|DRUG: SB-681323 Intravenous 7.5mg|DRUG: SB-681323 Intravenous 10mg|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Memantine Hydrochloride in Helping Cancer Survivors Stop Smoking
Status: COMPLETED
Conditions: Breast Cancer|Colorectal Cancer|Lung Cancer|Prostate Cancer|Tobacco Use Disorder
Interventions: DRUG: memantine hydrochloride|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Use of Seamguard to Prevent Leak and Bleeding in Gastrointestinal Surgery
Status: COMPLETED
Conditions: Leak on Lineal Stapled Anastomoses|Bleeding on Lineal Stapled Anastomoses
Interventions: DEVICE: Seamguard
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: NEO-adjuvant Chemo-immunotherapy in Pancreatic Cancer
Status: RECRUITING
Conditions: Pancreatic Cancer
Interventions: DRUG: Durvalumab|DRUG: Oxaliplatin|DRUG: Irinotecan|DRUG: Calcium folinate (leucovorin)|DRUG: Fluorouracil|DRUG: Pegylated G-CSF
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Manual Lymphatic Drainage on Acute and Post-acute Ankle Sprain in Athletes
Status: NOT_YET_RECRUITING
Conditions: Ankle Sprains
Interventions: OTHER: Manual lymphatic drainage. will be applied three days per week for four weeks.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Feasibility of Yoga for Type-2 Diabetes
Status: RECRUITING
Conditions: Type2 Diabetes
Interventions: BEHAVIORAL: Iyengar yoga|BEHAVIORAL: Standard Exercise|BEHAVIORAL: Nutrition Counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sublingual Versus Vaginal Misoprostol In Medical Treatment of First Trimestric Missed Miscarriage
Status: COMPLETED
Conditions: Missed Abortion
Interventions: DRUG: sublingual misoprostol|DRUG: vaginal misoprostol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Musical-animated Toys and Audio Books in Pediatric Palliative Care.
Status: COMPLETED
Conditions: Tracheostomy Infection
Interventions: OTHER: Listening to audiobook|OTHER: Playing musical-moving toy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Convection Enhanced Localized Administration of PRX321 With Real-time Imaging for Therapy of Recurrent Glioblastoma (CLARITY-1)
Status: WITHDRAWN
Conditions: Glioblastoma Multiforme
Interventions: DRUG: IL-4PE
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Observation of Patients With Primary Pulmonary Hypertension Receiving Prescribed Ventavis Inhalation Therapy Regarding Safety and Efficacy for up to 4 Years
Status: COMPLETED
Conditions: Hypertension, Pulmonary
Interventions: DRUG: Iloprost (Ventavis, BAYQ6256)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Interleukin-7 in Treating Patients With Metastatic Melanoma or Locally Advanced or Metastatic Kidney Cancer
Status: TERMINATED
Conditions: Kidney Cancer|Melanoma (Skin)
Interventions: BIOLOGICAL: recombinant interleukin-7|GENETIC: gene expression analysis|GENETIC: polymerase chain reaction|GENETIC: protein expression analysis|OTHER: flow cytometry|OTHER: immunoenzyme technique|OTHER: immunologic technique|OTHER: laboratory biomarker analysis|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Ipilimumab (MDX-010) Monotherapy in Patients With Previously Treated Unresectable Stage III or IV Melanoma
Status: COMPLETED
Conditions: Melanoma
Interventions: DRUG: ipilimumab (MDX-010, BMS-734016)|DRUG: Ipilimumab|DRUG: Ipilimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comb Effect of 4-7-8 Breathing Technique and Stationary Cycle on PP, QOL and Dyspnea in Post CABG Patients.
Status: RECRUITING
Conditions: Post-cardiac Surgery
Interventions: OTHER: 4-7-8 breathing technique|OTHER: Stationary Cycling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: ATHERO: Advanced Technology Halting Early Re-Stenosis and Occlusion
Status: WITHDRAWN
Conditions: Arterial Occlusive Disease|Intermittent Claudication
Interventions: DEVICE: Lower extremity Atherectomy and Cryoplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Determine the Activity of Caelyx With Trastuzumab and Docetaxel in the Treatment of Metastatic Breast Cancer (Study P03679)
Status: COMPLETED
Conditions: Breast Neoplasm
Interventions: DRUG: Pegylated Liposomal Doxorubicin|DRUG: Docetaxel|DRUG: Trastuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endometriosis and Microvascular Dysfunction: Role of Inflammation
Status: RECRUITING
Conditions: Endometriosis
Interventions: DRUG: Salsalate Pill|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: In Vivo PARP-1 Expression With 18F-FluorThanatrace PET/CT in Patients With Pheochromocytoma and Paraganglioma
Status: RECRUITING
Conditions: Pheochromocytoma|Paraganglioma
Interventions: DRUG: [18F]FluorThanatrace ([18F]FTT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Multi-Center Phase II Study to Compare MER-101 20mg Tablets to Intravenous Zometa 4mg in Male Bisphosphonate-Naive, Hormone Refractory Prostate Cancer Patients
Status: COMPLETED
Conditions: Hormone-Refractory Prostate Cancer
Interventions: DRUG: Zoledronic Acid 20mg Tablets|DRUG: Zoledronic Acid|DRUG: Zoledronic Acid 20mg Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Department of Defense PTSD Adaptive Platform Trial - Intervention C - Daridorexant
Status: RECRUITING
Conditions: Post Traumatic Stress Disorder
Interventions: DRUG: Intervention C Daridorexant|DRUG: Intervention C Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Indication of Permanent Cardiac Parcing After Tanscatheter Aortic Valve Implantation
Status: COMPLETED
Conditions: Aortic Valve Stenosis
Interventions: DEVICE: Pacemaker SORIN Group KORA DR|PROCEDURE: transcatheter aortic valve implantation (TAVI)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Subcuticular Absorbable Staples Versus Conventional Skin Closure in Women Undergoing Cesarean Delivery
Status: TERMINATED
Conditions: Operative Time|Wound Heal
Interventions: DEVICE: INSORB: subcuticular stapling device|DEVICE: Subcuticular monocryl suture manufactured by Ethicon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: The Specificity of Cervical Facet Medial Branch Blocks
Status: COMPLETED
Conditions: Neck Pain|Cervical Facet Arthropathy
Interventions: PROCEDURE: Cervical medial branch blocks|PROCEDURE: Cervical medial branch blocks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Guanfacine and Lidocaine Combination in Trigeminal Nerve Block for Pain Management in Trigeminal Neuropathy
Status: COMPLETED
Conditions: Trigeminal Neuralgia
Interventions: DRUG: Lidocaine|DRUG: Guanfacine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing Different Rehabilitation Exercise Strategies for Improving Arm Recovery After Stroke
Status: RECRUITING
Conditions: Stroke
Interventions: DEVICE: Boost - Moveable Wheelchair Armrest|BEHAVIORAL: Electronic Arm and Hand Exercise Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multidimensional Examination of Patients With Colorectal and Anal Cancer
Status: NOT_YET_RECRUITING
Conditions: Colorectal Cancer|Anal Cancer|Physical Inactivity|Fecal Incontinence|Quality of Life
Interventions: OTHER: No intervention - cross-sectional observational study
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Is Paracetamol an Effective Treatment for Chronic Moderate Pain in the Newborn After Operative Vaginal Delivery?
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Paracetamol|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Orofacial Functions and Masticatory Function in Children With Different Types of Deterioration in Oral Health
Status: RECRUITING
Conditions: Mastication|Disability|Oral Stage|Child Development
Interventions: PROCEDURE: dental treatment for global oral rehabilitation|OTHER: oral health check up
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Analysis of Ocular Deviations Between Dominant and Non-dominant Eye Using Video-oculography (VOG) in Intermittent Exotropia
Status: UNKNOWN
Conditions: Intermittent Exotropia|Strabismus
Interventions: DIAGNOSTIC_TEST: Video-oculography|DIAGNOSTIC_TEST: Alternative prism cover test
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: TactiFlex Paroxysmal Atrial Fibrillation IDE Trial
Status: COMPLETED
Conditions: Paroxysmal Atrial Fibrillation
Interventions: DEVICE: TactiFlex SE|DEVICE: TactiFlex SE - High Standard Power
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Low Dose Corticosteroids Efficiency, Associated With Myfortic ® in the Treatment of Nephrotic Syndrome
Status: COMPLETED
Conditions: Nephrotic Syndrome
Interventions: DRUG: Prednisone|DRUG: acid mycophenolic (Myfortic)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sofosbuvir With Peginterferon Alfa 2a and Ribavirin for 12 Weeks in Treatment-Naive Subjects With Chronic Genotype 1, 4, 5, or 6 HCV Infection
Status: COMPLETED
Conditions: Chronic Hepatitis C
Interventions: DRUG: Sofosbuvir|DRUG: RBV|DRUG: PEG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cediranib, Paclitaxel, and Carboplatin in Treating Patients With Stage IIIB or Stage IV Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DRUG: carboplatin|DRUG: cediranib maleate|DRUG: paclitaxel|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PillCam Colon Capsule and CT-colonography in the Evaluation of Patients With Incomplete Conventional Colonoscopy
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DEVICE: PillCam Colon Capsule Endoscopy (Given® Diagnostic System)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: TIBOHCA: Safety, Tolerability and Pharmacokinetics of 2-Iminobiotin (2-IB) After OHCA
Status: TERMINATED
Conditions: Cardiac Arrest|Hypoxic Ischemic Brain Injury
Interventions: DRUG: 2-Iminobiotin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Substitution of Acetate by Citrate in the Bicarbonate Based Hemodialysis
Status: UNKNOWN
Conditions: End Stage Renal Disease (ESRD)
Interventions: OTHER: Acetate by Citrate substitution and vice versa
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Combination Chemotherapy and Antithymocyte Globulin in Reducing Graft-Versus-Host Disease in Patients Undergoing Donor Stem Cell Transplantation For Myelodysplastic Syndrome or Myeloproliferative Disorder
Status: COMPLETED
Conditions: Chronic Myeloproliferative Disorders|Graft Versus Host Disease|Leukemia|Myelodysplastic Syndromes|Myelodysplastic/Myeloproliferative Diseases
Interventions: BIOLOGICAL: anti-thymocyte globulin|DRUG: busulfan|DRUG: cyclophosphamide|DRUG: cyclosporine|DRUG: methotrexate|PROCEDURE: allogeneic bone marrow transplantation|PROCEDURE: peripheral blood stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of Tissue Glue on PICC and Midline Catheters Insertion Sites
Status: RECRUITING
Conditions: Adult Patients With Mid-term or Long-term Venous Access
Interventions: DEVICE: Catheter fixation with surgical stitch|DEVICE: Catheter fixation with glue (cyanoacrylate tissue glue Secure PortIV)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study of REGN4018 Administered Alone or in Combination With Cemiplimab in Adult Patients With Recurrent Ovarian Cancer or Other Recurrent Mucin-16 Expressing (MUC16+) Cancers
Status: RECRUITING
Conditions: Recurrent Ovarian Cancer|Recurrent Fallopian Tube Cancer|Recurrent Primary Peritoneal Cancer|Recurrent Endometrial Cancer
Interventions: DRUG: REGN4018|DRUG: cemiplimab|DRUG: Sarilumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Intravitreal Aflibercept Injection (IAI; EYLEA®; BAY86-5321) in Patients With Diabetic Macular Edema
Status: COMPLETED
Conditions: Diabetic Macular Edema
Interventions: DRUG: Intravitreal Aflibercept Injection (IAI; EYLEA®; BAY86-5321)|PROCEDURE: Macular Laser Photocoagulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effect of Roflumilast in Hyperinflated COPD Patients Using Functional Respiratory Imaging
Status: TERMINATED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: RADIATION: HRCT scan|DRUG: Placebo of Roflumilast|DRUG: Roflumilast
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ringer's Lactate Versus Normal Saline in Caesarean Section
Status: COMPLETED
Conditions: Normal Anion Gap Metabolic Acidosis
Interventions: DRUG: 0.9% Normal Saline|DRUG: Ringer's Lactate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Self-regulated Constraint-induced Movement Therapy in Subacute Stroke Patients
Status: COMPLETED
Conditions: Stroke
Interventions: OTHER: Self-regulated constraint-induced movement therapy|OTHER: Constraint-induced movement therapy|OTHER: Conventional occupational therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of First-line Treatment With SG001 Plus Chemotherapy ± Bevacizumab Versus Placebo Plus Chemotherapy ±Bevacizumab for Recurrent, or Metastatic Cervical Cancer With PD-L1 Positive (CPS≥1)
Status: NOT_YET_RECRUITING
Conditions: Recurrent, or Metastatic Cervical Cancer With PD-L1 Positive (CPS≥1)
Interventions: DRUG: SG001 injection|DRUG: Paclitaxel|DRUG: Cisplatin|DRUG: Carboplatin|DRUG: Bevacizumab injection|DRUG: SG001 placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Protection of the Heart With Doxycycline During Coronary Artery Bypass Grafting
Status: COMPLETED
Conditions: Coronary Artery Bypass Grafting|Cardiopulmonary Bypass|Reperfusion Injury
Interventions: DRUG: Periostat|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Proof of Concept Study With Rituximab in Patients With CIDP Not Responding to Conventional Immune Therapy
Status: ACTIVE_NOT_RECRUITING
Conditions: Polyradiculoneuropathy, Chronic Inflammatory Demyelinating
Interventions: DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pomalidomide and Dexamethasone Effects in Multiple Myeloma Patients With Del 17p or t (4;14)
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: POMALIDOMIDE|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Magnesium Sulphate Injection in Treatment of Myofascial Trigger Points
Status: COMPLETED
Conditions: Trigger Point Pain, Myofascial
Interventions: DRUG: Magnesium sulfate|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Banding Versus Propranolol for Primary Prophylaxis of Variceal Bleeding
Status: TERMINATED
Conditions: Liver Cirrhosis|Esophageal Varices
Interventions: PROCEDURE: endoscopic variceal banding|DRUG: propranolol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Trial of Enteral Nutrition Enriched With Eicosapentaenoic Acid (EPA) in Upper Gastrointestinal Cancer Surgery
Status: UNKNOWN
Conditions: Esophageal Cancer
Interventions: DIETARY_SUPPLEMENT: Prosure|DIETARY_SUPPLEMENT: Ensure Plus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: South Asian Arrhythmogenic Cardiomyopathy Registry
Status: UNKNOWN
Conditions: Arrhythmogenic Right Ventricular Cardiomyopathy|Arrhythmogenic Right Ventricular Dysplasia|Arrhythmogenic Ventricular Cardiomyopathy|Arrhythmogenic Cardiomyopathy|Ventricular Tachycardia|Sudden Cardiac Death
Interventions: DIAGNOSTIC_TEST: ECG|DIAGNOSTIC_TEST: Echocardiography|DIAGNOSTIC_TEST: Cardiac MRI|DIAGNOSTIC_TEST: Ambulatory ECG recording|DIAGNOSTIC_TEST: Cardiac EP study|GENETIC: All study subjects will undergo sample collection for genetic testing.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Prospective Randomized Trial of Prostate Biopsy Protocols Comparing the Vienna Nomogram and a Standard 10-core Biopsy Scheme
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: PROCEDURE: 10-core prostate biopsy protocol|PROCEDURE: Vienna nomogram prostate biopsy protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: RIVAroxaban Versus Low-molecular Weight Heparin in Patients With Lower Limb Trauma Requiring Brace or CASTing
Status: RECRUITING
Conditions: Venous Thromboembolism|Deep Vein Thrombosis|Pulmonary Embolism|Lower Limb Trauma|Thromboprophylaxis|Immobilisation
Interventions: DRUG: Rivaroxaban 10 MG|DRUG: Low Heparin Molecular Weight
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Two Part Study (306A/306B) to Assess Droxidopa in Treatment of NOH in Patients With Parkinson's Disease
Status: COMPLETED
Conditions: Orthostatic Hypotension|Parkinson's Disease
Interventions: DRUG: Droxidopa|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Preventing Parental Opioid and/or Methamphetamine Addiction Within DHS-Involved Families: FAIR
Status: ACTIVE_NOT_RECRUITING
Conditions: Opioid-Related Disorders|Stimulant-Related Disorder|Child Neglect|Mental Health Impairment
Interventions: BEHAVIORAL: Families Actively Improving Relationships (FAIR)|BEHAVIORAL: Standard Case Management and Referral
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Clinical Trial to Assess Pharmacokinetic Profiles, Safety and Tolerability of IVL3004 and IVL4002 in Healthy Male Subjects.
Status: NOT_YET_RECRUITING
Conditions: Opioid Dependence|Alcohol Dependence
Interventions: DRUG: Vivitrol Injectable Product|DRUG: IVL3004|DRUG: IVL4002
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of AVB-S6-500 (Batiraxcept) in Patients With Advanced or Metastatic Clear Cell Renal Cell Carcinoma
Status: TERMINATED
Conditions: Clear Cell Renal Cell Carcinoma
Interventions: DRUG: Batiraxcept|DRUG: Cabozantinib (Cabo)|DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Efficacy and Safety of PerOx Quench on the Prevention of Oxaliplatin Treatment Induced Neuropathy
Status: TERMINATED
Conditions: Colorectal Cancer|Advanced Gastric Cancer|Neuropathy
Interventions: DIETARY_SUPPLEMENT: PerOx Quench|DIETARY_SUPPLEMENT: PerOx Quench Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Mersey Acute Coronary Syndrome Rule-Out Using High Sensitive Troponin
Status: COMPLETED
Conditions: Acute Coronary Syndrome|Angina Pectoris|Cardiovascular Diseases|Chest Pain|Heart Diseases|Myocardial Ischemia|Heart Attack|Chest Pain Atypical Syndrome|Angina, Unstable|Myocardial Infarction
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pilot Study of Magnesium Infusions in Pediatric Asthma
Status: WITHDRAWN
Conditions: Asthma
Interventions: DRUG: Magnesium Sulfate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety of Co-administration of IDA and Azithromycin for NTDs ( ComboNTDs )
Status: COMPLETED
Conditions: Trachoma|Yaws|Lymphatic Filariases|Scabies|Strongyloidiasis
Interventions: DRUG: Albendazole on Day 1|DRUG: Ivermectin on Day 1|DRUG: Diethylcarbamazine on day 1|DRUG: Azithromycin on Day 1|DRUG: Azithromycin on Day 8
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Azithromycin Versus Doxycycline on Restistin Level in Periodontitis Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Periodontal Diseases|Type 2 Diabetes
Interventions: DRUG: Group I|DRUG: Group II|DRUG: Group III
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparison of Tiotropium and Ipratropium in a Double-Blind, Double-dummy, Efficacy and Safety Study in Adults With COPD
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Tiotropium|DRUG: Ipratropium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial In The Treatment Of Allogeneic Post-Transplant Cytopenias With Sequential Infusion Of Allogeneic Mesenchymal Cells Expanded In Vitro
Status: COMPLETED
Conditions: Cytopenia
Interventions: BIOLOGICAL: Sequential infusion of allogeneic mesenchymal stem cells expanded "in vitro"
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bimatoprost Ocular Insert Compared to Topical Timolol Solution in Patients With Glaucoma or Ocular Hypertension
Status: COMPLETED
Conditions: Primary Open-Angle Glaucoma|Ocular Hypertension
Interventions: DRUG: Bimatoprost|DRUG: Timolol 0.5%|DRUG: Placebo Eye Drops|DEVICE: Placebo Ocular Insert
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: RESOLUTE Japan - The Clinical Evaluation of the MDT-4107 Drug-Eluting Coronary Stent
Status: COMPLETED
Conditions: Arterial Occlusive Diseases|Myocardial Ischemia|Cardiovascular Diseases|Coronary Artery Disease
Interventions: DEVICE: MDT-4107 Drug Eluting Stent
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Chemoradiotherapy Combined With Tislelizumab in the Treatment of Locally Advanced Rectal Cancer
Status: NOT_YET_RECRUITING
Conditions: Immunotherapy
Interventions: DRUG: Tislelizumab|DRUG: Capecitabine|DRUG: oxaliplatin|RADIATION: short-range radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT