pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Comparison of CO-OP and GDT on Occupational Performance and Functional Status in the CP
Status: COMPLETED
Conditions: Cerebral Palsy|Occupational Problems|Cognitive Orientation|Goals
Interventions: OTHER: CO-OP|OTHER: GDT|OTHER: traditional occupational therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Vosaroxin or Placebo in Combination With Cytarabine in Patients With First Relapsed or Refractory AML
Status: COMPLETED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: vosaroxin + cytarabine|DRUG: placebo + cytarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Reduction of Rocuronium-induced Injection Pain With Aspiration of Blood
Status: COMPLETED
Conditions: Anesthesia, General
Interventions: DRUG: rocuronium-normal-saline mixture|DRUG: rocuronium-lidocaine mixture|DRUG: rocuronium-blood mixture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Early Onset Colorectal Cancer Detection
Status: RECRUITING
Conditions: Colorectal Cancer|Colorectal Neoplasms|Colorectal Adenocarcinoma|Colorectal Cancer Stage I|Colorectal Cancer Stage IV|Colorectal Cancer Stage II|Colorectal Cancer Stage III|Colorectal Neoplasms Malignant
Interventions: DIAGNOSTIC_TEST: ENCODE
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Incidence and Clinical Impact of Serum Hyperamylasemia (POH) After Pancreatectomy on Postoperative Outcome and Patient Safety
Status: RECRUITING
Conditions: Pancreatectomy|Hyperamylasemia|Pancreatitis, Acute
Interventions: OTHER: Pancreatectomy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Structured Non-operative Treatment of Knee Osteoarthritis
Status: COMPLETED
Conditions: Osteoarthritis of the Knee
Interventions: OTHER: Neuromuscular training (NEMEX-TJR)|BEHAVIORAL: Information|DRUG: Paracetamol|DRUG: Burana|DRUG: Pantoprazole|BEHAVIORAL: Dietary counseling|BEHAVIORAL: Patient education|OTHER: Insoles
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Nebulized Albuterol on Donor Oxygenation
Status: COMPLETED
Conditions: Brain Death|Organ Donor|Pulmonary Edema
Interventions: DRUG: Albuterol|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Femoral Nerve Block Versus Fascia Iliaca Compartment Block for Pain Control in Traumatic Femur Fracture Repair in Pediatric Population
Status: RECRUITING
Conditions: Regional Anesthesia Morbidity
Interventions: PROCEDURE: Fascia Iliaca compartment block group|PROCEDURE: Femoral nerve block group|PROCEDURE: General care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Infliximab Therapy for Dolichoectactic Vertebrobasilar Aneurysms
Status: ENROLLING_BY_INVITATION
Conditions: Aneurysm|Stroke|Vasculitis|Tumor Necrosis Factor-alpha
Interventions: DRUG: Infliximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Tiragolumab Plus Atezolizumab Compared With Placebo Plus Atezolizumab in Participants With Completely Resected Non-small Cell Lung Cancer Who Have Received Adjuvant Platinum-based Chemotherapy
Status: RECRUITING
Conditions: Non-small Cell Lung Cancer (NSCLC)
Interventions: DRUG: Atezolizumab|DRUG: Tiragolumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Medrol Dosepak Taper for Delayed Post-op Recovery After TKA
Status: TERMINATED
Conditions: Total Knee Arthroplasty
Interventions: DRUG: Methylprednisolone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Hypnopuncture for In Vitro Fertilization (IVF)
Status: TERMINATED
Conditions: Infertility
Interventions: OTHER: Hypnopuncture (Hypnosis+Acupuncture)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Physiological Effects of N-Acetyl Cysteine in Patients With Multiple Sclerosis
Status: ENROLLING_BY_INVITATION
Conditions: Multiple Sclerosis
Interventions: DIETARY_SUPPLEMENT: N-acetyl Cysteine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Immunogenicity of a Candidate Tuberculosis (TB) Vaccine in Adults With TB Disease
Status: TERMINATED
Conditions: Tuberculosis
Interventions: BIOLOGICAL: GSK Biologicals' investigational TB vaccine GSK 692342|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: VEGF Trap and Docetaxel in Treating Patients With Persistent or Recurrent Ovarian Epithelial Cancer, Primary Peritoneal Cancer, or Fallopian Tube Cancer
Status: COMPLETED
Conditions: Fallopian Tube Cancer|Malignant Tumor of Peritoneum|Recurrent Ovarian Epithelial Cancer
Interventions: DRUG: docetaxel|BIOLOGICAL: ziv-aflibercept|OTHER: laboratory biomarker analysis|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stool Ritual: Impact on the Number of Nights Without Stools Among Dependent Residents in Institutions for Dependent Elderly People
Status: COMPLETED
Conditions: Homes for the Aged|Intestinal Elimination
Interventions: OTHER: Ritual of stool|OTHER: Usual practice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Internet-Based and Established Dyspnea Self-Management Programs in Chronic Obstructive Pulmonary Disease (COPD) Patients
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: BEHAVIORAL: Internet-based Dyspnea Self-Management Program|BEHAVIORAL: Face-to-face Dyspnea Self-Management Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Autologous Fat Transfer on Preventing Expanded Skin From Expansion Failure
Status: COMPLETED
Conditions: Scar|Nevus
Interventions: PROCEDURE: Fat grafting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Effectiveness, Safety, and Microbiology Study of Doripenem in Patients With Nosocomial (Hospital-acquired) Pneumonia
Status: COMPLETED
Conditions: Pneumonia|Bacterial Pneumonia|Ventilator-Associated Pneumonia|Infections, Nosocomial
Interventions: DRUG: doripenem
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy With or Without Bone Marrow Transplantation in Treating Patients With Acute Promyelocytic Leukemia
Status: UNKNOWN
Conditions: Leukemia
Interventions: DRUG: busulfan|DRUG: cyclophosphamide|DRUG: cytarabine|DRUG: etoposide|DRUG: idarubicin|DRUG: mercaptopurine|DRUG: methotrexate|DRUG: mitoxantrone hydrochloride|DRUG: thioguanine|DRUG: tretinoin|PROCEDURE: allogeneic bone marrow transplantation|PROCEDURE: autologous bone marrow transplantation|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Acute Impact of Cardiac Resynchronization on Vascular Function (RVA-CRT)
Status: COMPLETED
Conditions: Heart Failure
Interventions: DEVICE: Cardiac Resynchronization Therapy (ON vs. OFF)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Study of Motilitone to Treat Functional Dyspepsia
Status: COMPLETED
Conditions: Dyspepsia
Interventions: DRUG: Motilitone 30mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Reconstruction of Peri-implant Osseous Defects: A Randomized Trial
Status: COMPLETED
Conditions: Peri-implantitis
Interventions: DEVICE: Tigran PTG|PROCEDURE: Surgical intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Donor Derived, Multi-virus-specific, Cytotoxic T-Lymphocytes for Relapsed/Refractory Neuroblastoma
Status: COMPLETED
Conditions: Neuroblastoma
Interventions: BIOLOGICAL: GD2 CAR modified Tri-virus specific cytotoxic t-cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Innovative Strategies to Increase ART Initiation and Viral Suppression Among HIV-positive Men in Malawi
Status: ACTIVE_NOT_RECRUITING
Conditions: Hiv
Interventions: OTHER: Home-Based ART|OTHER: Facility-Based ART
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fluorescent Light Bronchoscopy Plus White Light Bronchoscopy for Early Detection of Lung Cancer
Status: COMPLETED
Conditions: Head and Neck Cancer|Lung Cancer
Interventions: OTHER: cytology specimen collection procedure|OTHER: immunohistochemistry staining method|OTHER: sputum cytology|PROCEDURE: bronchoscopic and lung imaging studies|PROCEDURE: bronchoscopy|PROCEDURE: comparison of screening methods|PROCEDURE: endoscopic biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: SCREENING
Clinical trial: A Randomized Clinical Trial of Megestrol Acetate as an Appetite Stimulant in Malnourished Children With Cancer
Status: COMPLETED
Conditions: Malnourished Children With Cancer
Interventions: DRUG: Megstrol Acetate|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study Comparing Tigecycline and Imipenem/Cilastatin in Chinese Subjects With Complicated Intra-Abdominal Infections
Status: COMPLETED
Conditions: Abdominal Abscess
Interventions: DRUG: tigecycline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Banana Flower Extract in the Efficacy Verification Program of Hair and Body Health Care
Status: COMPLETED
Conditions: Hair Loss
Interventions: DIETARY_SUPPLEMENT: Placebo sachet|DIETARY_SUPPLEMENT: Banana flower extract sachet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Covered or Uncovered Bile Duct Stents
Status: COMPLETED
Conditions: Bile Duct Neoplasms
Interventions: DEVICE: covered or uncovered stents
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of a Care Management System to Reduce Unmet Needs of Informal Caregivers of People With Dementia
Status: COMPLETED
Conditions: Dementia|Caregiver Burnout|Carer Stress Syndrome|Relatives|Partner, Domestic
Interventions: OTHER: Care Management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: IS-free Treg HaploHCT
Status: RECRUITING
Conditions: Stem Cell Transplant Complications|Graft Vs Host Disease|Myeloid Leukemia, Acute|Myeloid Leukemia in Relapse (Disorder)|Myelodysplastic Syndromes
Interventions: RADIATION: Radiation|DRUG: Fludarabine|DRUG: Thiotepa|DRUG: Cyclophosphamide|DRUG: Mesna|BIOLOGICAL: Treg-enriched donor cell|BIOLOGICAL: Unmodified donor T Cell|PROCEDURE: CD34+ Haplo Peripheral Blood Stem Cell
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sex-specific Determinants of Early-phase Recovery From Skeletal Muscle Disuse
Status: RECRUITING
Conditions: Atrophy of Muscle Due to Disuse|Rehabilitation
Interventions: OTHER: Resistance Exercise Rehabilitation|OTHER: Walking-based rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Leukotriene Antagonism in Recruitment of CD49d Expressing Neutrophils in Atopic Subjects
Status: COMPLETED
Conditions: Nasal Allergy
Interventions: PROCEDURE: Nasal lavage|PROCEDURE: Nasal allergen challenge|PROCEDURE: Epicutaneous skin testing|PROCEDURE: Peripheral blood|DRUG: Montelukast 10Mg Tablet|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Clinical Trial to Evaluate the Tolerability and the Pharmacokinetics of CKD-348
Status: COMPLETED
Conditions: Hypertension and Dyslipidemia
Interventions: DRUG: CKD-348(4) F1|DRUG: CKD-348(4) F2|DRUG: CKD-828, D097, D337
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Paclitaxel/Carboplatin With or Without Bavituximab in Previously Untreated Non Small-Cell Lung Cancer
Status: COMPLETED
Conditions: Non-Squamous Non-Small Cell Lung Cancer
Interventions: DRUG: Paclitaxel / Carboplatin|DRUG: bavituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Changes in Gut Hormones, Body Composition and Energy Expenditure After Roux-en-Y
Status: COMPLETED
Conditions: Obesity|Weight Loss
Interventions: OTHER: Resting Metabolic Rate (RMR)|OTHER: Duel-energy x-ray absorptiometry (DEXA)|OTHER: Visual Analog Scale (VAS)|OTHER: Meal Stimulation Test
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Docetaxel and Capecitabine in Treating Patients With Recurrent or Persistent Ovarian Epithelial Cancer, Fallopian Tube Cancer, or Peritoneal Cavity Cancer
Status: TERMINATED
Conditions: Fallopian Tube Cancer|Ovarian Cancer|Peritoneal Cavity Cancer
Interventions: DRUG: capecitabine|DRUG: docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Nucleus Basalis of Meynert Stimulation on Cognitive Disorders in Dementia With Lewy Bodies
Status: COMPLETED
Conditions: Dementia With Lewy Bodies
Interventions: PROCEDURE: Electrical stimulation of the nucleus basalis of Meynert
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I Mitomycin Combined With Bacillus Calmette-Guérin (BCG) for Bladder Cancer
Status: COMPLETED
Conditions: Urinary Bladder Neoplasm
Interventions: DRUG: Mitomycin C
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intra-operative Fraction of Inspired Oxygen and Lung Injury in Coronary Artery Bypass Grafting Surgery
Status: WITHDRAWN
Conditions: Lung Injury|Pulmonary Complication
Interventions: OTHER: Fraction of Inspired Oxygen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: OTL38 Injection for Intraoperative Imaging of Folate Receptor Positive Lung Nodules
Status: COMPLETED
Conditions: Lung Neoplasms|Lung Cancer
Interventions: DRUG: OTL38 for Injection|DEVICE: Near infrared camera imaging system|PROCEDURE: Endoscopic or Thoracic Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: POTENTE Study: A Study of Early Virological Response in Naive Patients With Chronic Hepatitis C, Genotype 2 or 3, Treated With PEGASYS (Peginterferon Alfa-2a (40KD)) Plus Copegus (Ribavirin).
Status: COMPLETED
Conditions: Hepatitis C, Chronic
Interventions: DRUG: peginterferon alfa-2a [Pegasys]|DRUG: ribavirin [Copegus]
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: BAY-43-9006 in Advanced, Metastatic Soft Tissue Sarcomas
Status: COMPLETED
Conditions: Sarcoma, Soft Tissue
Interventions: DRUG: Sorafenib (BAY-43-9006)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transcranial Photobiomodulation With Near-Infrared Light for Language in Individuals With Down Syndrome
Status: ACTIVE_NOT_RECRUITING
Conditions: Down Syndrome
Interventions: DEVICE: Near-Infrared Transcranial Photobiomodulation|DEVICE: Sham Transcranial Photobiomodulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Individualized Lung-protective Ventilation With Lung Dynamic Compliance-guided Positive End-expiratory Pressure(PEEP) Titration on Postoperative Pulmonary Complications of Pediatric Video-assisted Thoracoscopic Surgery
Status: ENROLLING_BY_INVITATION
Conditions: Anesthesia|Surgery
Interventions: PROCEDURE: Conventional positive end-expiratory pressure(PEEP)|PROCEDURE: Lung dynamic compliance guided positive end-expiratory pressure(PEEP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: EFFECT OF CRYOLIPOLYSIS ON HORMONAL PROFILE AND MENSTRUAL REGULARITYIN OBESE WITH PCOS
Status: COMPLETED
Conditions: Obese Women With PCOS
Interventions: DEVICE: Cryolipolysis device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Autologous Bone Marrow Derived Stem Cell Treatment in Amyotrophic Lateral Sclerosis
Status: COMPLETED
Conditions: Amyotrophic Lateral Sclerosis|ALS
Interventions: BIOLOGICAL: HYNR-CS inj|OTHER: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Resistive Diaphragmatic Breathing Exercise With Pursed Lips Breathing Exercise in Sub-acute Stroke Patients
Status: COMPLETED
Conditions: Stroke, Ischemic
Interventions: OTHER: Resistive Diaphragmatic breathing exercise|OTHER: Diaphragmatic breathing exercise|OTHER: Conventional stroke physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Accute Effect of B-Turmactive Both on Mild and Moderate Knee Pain on Healthy Volunteers
Status: COMPLETED
Conditions: Knee Injuries|Inflammation Knees
Interventions: DIETARY_SUPPLEMENT: B-turmactive|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II of AUY922 in Second-line Gastric Cancer in Combination With Trastuzumab in HER2 Positive Patients
Status: TERMINATED
Conditions: Advanced Gastric Cancer
Interventions: DRUG: AUY922|DRUG: Trastuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Probiotics in Enteral Feeding in Critically Ill Patients
Status: COMPLETED
Conditions: Critical Illness|Dietary Modification|Probiotics|Gut Failure|Treatment Outcomes
Interventions: DRUG: Probiotics|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic and Pharmacodynamic Profiles of Albuterol Spiromax® and ProAir® Hydrofluoroalkane (HFA) in Pediatric Patients With Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Albuterol Spiromax®|DRUG: ProAir® HFA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Osteopathic Treatment in Patients With Tension Type Headache
Status: NOT_YET_RECRUITING
Conditions: Tension-Type Headache
Interventions: OTHER: Cranial listening technique|OTHER: Suboccipital muscles inhibition technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of High Intensity Children's Games Compared With Medium Intensityregulation, Obesity Biomarkers and Body Composition in Boys and Girls
Status: UNKNOWN
Conditions: Obesity, Childhood
Interventions: OTHER: High-Intensity Interval Training|OTHER: Medium-Intensity Interval Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Breast Fibroadenoma With High Intensity Focused Ultrasound (HIFU)
Status: TERMINATED
Conditions: Breast Fibroadenoma
Interventions: PROCEDURE: Surgery|DEVICE: HIFU (Echopulse)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dystonia Image-based Programming of Stimulation: A Prospective, Randomized, Double-blind Crossover Trial
Status: RECRUITING
Conditions: Dystonia|Deep Brain Stimulation
Interventions: OTHER: DBS programming
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dose Escalation of OXi4503 as Single Agent and Combination With Cytarabine w/Subsequent Ph 2 Cohorts for AML and MDS
Status: UNKNOWN
Conditions: Acute Myelogenous Leukemia|Myelodysplastic Syndromes
Interventions: DRUG: Phase 1 - OXi4503|DRUG: Phase 1 - OXi4503 + cytarabine|DRUG: Phase 2 - OXi4503 + cytarabine|DRUG: Phase 2 - OXi4503 + cytarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial in 22q13 Deletion Syndrome(Phelan-McDermid Syndrome)
Status: COMPLETED
Conditions: 22q13 Deletion Syndrome|Phelan-McDermid Syndrome
Interventions: DRUG: Insulin-Like Growth Factor-1 (IGF-1)|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Manipulating Expectations in a Gratitude Intervention
Status: COMPLETED
Conditions: Gratitude + No Expectations|Gratitude + Expectations|Events Control
Interventions: BEHAVIORAL: Gratitude + No Expectations Intervention|BEHAVIORAL: Gratitude + Expectations Intervention|BEHAVIORAL: Events Control Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: The Effects of Intranasal and Oral Administration of Oxytocin on Responses to Emotional Scenes
Status: UNKNOWN
Conditions: Healthy
Interventions: DRUG: Oral Oxytocin|DRUG: Intranasal Oxytocin|DRUG: Oral placebo|DRUG: Intranasal placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Shock Wave Versus Vacuum Assisted Closure on Chronic Diabetic Foot Ulcer
Status: COMPLETED
Conditions: Chronic Diabetic Foot Ulcer
Interventions: DEVICE: Shock wave therapy|DEVICE: Vacuum-assisted closure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Recombinant Human C1 Inhibitor for the Treatment of Acute Attacks in Patients With Hereditary Angioedema
Status: COMPLETED
Conditions: Hereditary Angioedema|Angioneurotic Edema|Genetic Disorders
Interventions: DRUG: recombinant human C1 inhibitor|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Analysis of the Real-world Prescription Pattern of Palbociclib Combination Therapy With Aromatase Inhibitor as a First Line Therapy in Metastatic Breast Cancer Patients Using the National Health Insurance Claims Data in South Korea
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Breast Cancer
Interventions: DRUG: Patients who received Palbociclib as first line therapy in MBC setting
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: ALK33BUP-101: Safety and Pharmacodynamic Effects of ALKS 33-BUP Administered Alone and When Co-administered With Cocaine
Status: COMPLETED
Conditions: Cocaine Abuse
Interventions: DRUG: ALKS 33-BUP|DRUG: ALKS 33|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Anti-inflammatory Effect of Atorvastatin in Atherosclerotic Plaques Assessed by FDG-PET Imaging
Status: UNKNOWN
Conditions: Atherosclerosis|Inflammation
Interventions: DRUG: Atorvastatin|BEHAVIORAL: Lifestyle counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: S9917, Selenium in Preventing Cancer in Patients With Neoplasia of the Prostate
Status: COMPLETED
Conditions: Precancerous/Nonmalignant Condition|Prostate Cancer
Interventions: DRUG: L-selenomethionine|DRUG: L-selenomethionine placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Study of the Effects of Oral AT1001 (Migalastat Hydrochloride) in Patients With Fabry Disease
Status: COMPLETED
Conditions: Fabry Disease
Interventions: DRUG: migalastat hydrochloride|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Drug Interaction Study Between Tocilizumab, Methotrexate and Simvastatin on Patients With Rheumatoid Arthritis.
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: tocilizumab [RoActemra/Actemra]|DRUG: Methotrexate|DRUG: Simvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability of Trospium Chloride and Metformin Hydrochloride in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Trospium Chloride (Sanctura XR®)|DRUG: Metformin hydrochloride (Glucophage®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: A Phase 1 Study of UB-VV111 With and Without Rapamycin in Relapsed/Refractory CD19+ B-cell Malignancies
Status: NOT_YET_RECRUITING
Conditions: Lymphoma, B-Cell|Lymphoma, Non-Hodgkin (NHL)|Lymphoma, Large B-Cell, Diffuse (DLBCL)|Chronic Lymphocytic Leukemia (CLL)
Interventions: GENETIC: UB-VV111|DRUG: rapamycin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence of a Linagliptin / Metformin Fixed-dose Combination (FDC) Tablet Compared With Single Linagliptin and Metformin Tablets Administered Together in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Linagliptin/Metformin FDC|DRUG: Linagliptin|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Ivaltinostat Plus Capecitabine or Capecitabine in Metastatic Pancreatic Adenocarcinoma
Status: RECRUITING
Conditions: Metastatic Pancreatic Adenocarcinoma
Interventions: DRUG: Ivaltinostat|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Proton Radiotherapy With Chemotherapy for Nasopharyngeal Carcinoma
Status: COMPLETED
Conditions: Nasopharyngeal Carcinoma
Interventions: RADIATION: Proton/Photon Radiotherapy|DRUG: Cisplatin|DRUG: Fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Clavamox, Powder for Oral Suspension, 400 mg + 57 mg / 5 ml (Pharmtechnology LLC, Belarus), and Augmentin®, Powder for Oral Suspension, 400 mg + 57 mg / 5 ml (GlaxoSmithKline Trading CJSC, Russia), in Healthy Volunteers Under Fasting Conditions
Status: COMPLETED
Conditions: Bioequivalence
Interventions: DRUG: Clavamox|DRUG: Augmentin®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Assessment of Serum FAM19A5 Level in Egyptian Patients With Neuromyelitis Optica Spectrum Disorder
Status: UNKNOWN
Conditions: Assessment of Serum FAM19A5level in Egyptian Patients With NMOSD
Interventions: DIAGNOSTIC_TEST: serum level of FAM19A5
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study Comparing Sems Placement With and and Without Biliary Sphincterectomy in Patients With Malignant Biliary Obstruction
Status: UNKNOWN
Conditions: Bile Duct Obstruction
Interventions: PROCEDURE: ERCP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Evaluate the Efficacy Beyond Progression of Vemurafenib+Cobimetinib Associated With Local Treatment Compared to Second-line Treatment in Patients With BRAFV600+ Metastatic Melanoma in Focal Progression With First-line+Vemurafenib+Cobimetinib.
Status: UNKNOWN
Conditions: Melanoma Metastatic|BRAF V600 Mutation
Interventions: OTHER: Experimental combination beyond Focal Progression|DRUG: Pembrolizumab or Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Therapy for Age-Related Macular Degeneration.
Status: COMPLETED
Conditions: Age Related Macular Degeneration
Interventions: DRUG: Avastin (Bevacizumab)|DRUG: Bevacizumab|DRUG: Bevacizumab|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pragmatic Trial of the Effect of a Mailed Patient Flyer About Prostate Specific Antigen (PSA) Testing Prior to an Annual Exam
Status: COMPLETED
Conditions: Prostate Cancer Screening
Interventions: OTHER: PSA flyer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Early Initiated Vasopressor Therapy in the Emergency Department
Status: RECRUITING
Conditions: Shock|Shock, Septic|Hypotension|Hypotension and Shock|Hypotension Symptomatic|Hypovolemia|Hypovolemic Shock|Hypovolemic
Interventions: DRUG: Noradrenaline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating Behavioral Treatments to Improve Adherence to CPAP in People With Obstructive Sleep Apnea
Status: COMPLETED
Conditions: Adherence to CPAP in Obstructive Sleep Apnea
Interventions: BEHAVIORAL: Motivational Enhancement Therapy|BEHAVIORAL: Educational Counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Clinical Trial of the Safety, Pharmacokinetics and Hematologic Effects of Imatinib on Myelopoiesis in Adults When Given With and Without Isoniazid and Rifabutin
Status: COMPLETED
Conditions: Tuberculosis
Interventions: DRUG: Imatinib|DRUG: Isoniazid|DRUG: Rifabutin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trying Activity in Kidney Cancer Survivors (TRACKS) Trial
Status: COMPLETED
Conditions: Supervised Physical Activity Plus Exercise Counseling|Supervised Physical Activity Plus Behavioural Counseling
Interventions: BEHAVIORAL: Trying Activity for Kidney Cancer Survivors (TRACKS) Trial
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effectiveness of AlloWrap® for the Reduction of Inflammation in ACDF Procedures
Status: ENROLLING_BY_INVITATION
Conditions: Cervical Stenosis|Spondylolisthesis|Cervical Radiculopathy|Cervical Disc Disorder
Interventions: OTHER: AlloWrap® Amniotic Membrane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Thinking Skills at Work: Cognitive Remediation Therapy for Patients With Serious Mental Illness
Status: COMPLETED
Conditions: Schizophrenia and Related Disorders|Psychotic Disorder
Interventions: BEHAVIORAL: Cognitive Remediation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Study Comparing a Vaccine Transcutaneous Administration to the Intramuscular Route
Status: COMPLETED
Conditions: Healthy Volunteers|HIV Infection
Interventions: BIOLOGICAL: Transcutaneous mode of administration|BIOLOGICAL: Intramuscular mode of administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Positron Emission Tomography and CT Scan in Predicting Response in Patients With Metastatic Melanoma or Kidney Cancer Who Are Undergoing Cellular Adoptive Immunotherapy on a Surgery Branch Clinical Trial
Status: COMPLETED
Conditions: Kidney Cancer|Melanoma (Skin)
Interventions: PROCEDURE: computed tomography|PROCEDURE: positron emission tomography|RADIATION: fludeoxyglucose F 18
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: DIAGNOSTIC
Clinical trial: Intravenous Labetalol Versus Hydralazine in Preeclampsia
Status: ACTIVE_NOT_RECRUITING
Conditions: Preeclampsia Severe
Interventions: DRUG: Labetalol Injection|DRUG: HydrALAZINE Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: TAS-102 Combined With Bevacizumab and Tislelizumab Third-line or Above in the Treatment of Liver Metastasis in Colorectal Cancer
Status: UNKNOWN
Conditions: Immunotherapy|Colorectal Cancer
Interventions: DRUG: Tislelizumab|DRUG: bevacizumab|DRUG: TAS-102
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Development and Application of Intelligent Diagnosis and Treatment Norms for Children and Adolescents With Mental Disorders
Status: RECRUITING
Conditions: Depressive Disorder|AD|ASD|ADHD
Interventions: BEHAVIORAL: functional training|OTHER: Observation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Phase II Study To Assess Safety and Efficacy Of Short-Course Regimens Of Amphotericin B Emulsion In Kala-Azar
Status: COMPLETED
Conditions: Visceral Leishmaniasis
Interventions: DRUG: Amphotericin B fat emulsion in visceral leishmaniasis|DRUG: Amphotericin B fat emulsion|DRUG: Amphotericin B in fat emulsion
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Detection of Early Esophageal Cancer by NIR-FME.
Status: UNKNOWN
Conditions: Barrett Esophagus
Interventions: DRUG: Bevacizumab-IRDye800CW|DIAGNOSTIC_TEST: Fluorescence endoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Disease Management Program or Usual Care in Patients With Stage III or Stage IV Lung Cancer, Pancreatic Cancer, Ovarian Cancer, or Colorectal Cancer, and Their Caregivers
Status: COMPLETED
Conditions: Colorectal Cancer|Lung Cancer|Ovarian Cancer|Pancreatic Cancer
Interventions: OTHER: questionnaire administration|PROCEDURE: quality-of-life assessment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Prospective Study on the Role of Intravenous Unfractionated Heparin Following Digital Replantation and Revascularization
Status: RECRUITING
Conditions: Amputation; Traumatic, Hand
Interventions: DRUG: Intravenous unfractionated heparin|DRUG: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase Ia Malaria Vaccine Trial of Two Virosome-Formulated Peptides
Status: TERMINATED
Conditions: Falciparum Malaria
Interventions: BIOLOGICAL: Virosome-formulated synthetic peptides (malaria vaccine)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: PREVENTION
Clinical trial: Molecular Imaging Visualization of Tumor Heterogeneity in Non-small Cell Lung Cancer
Status: UNKNOWN
Conditions: NSCLC|PET/CT|Biopsy|Radiomics|Genomics|Whole-exome Sequencing
Interventions: DIAGNOSTIC_TEST: 18F-FDG PET/CT and PET/CT-guide targeted biopsy in another group of participants
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Remote Ischaemic Preconditioning in Children Undergoing Cardiac Surgery
Status: COMPLETED
Conditions: Ischaemic Reperfusion Injury
Interventions: PROCEDURE: Remote ischaemic preconditioning (RIPC)|PROCEDURE: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Dietary Supplement for the Prevention of Cognitive Decline in a Very Elderly Population.
Status: UNKNOWN
Conditions: Mild Cognitive Impairment
Interventions: DIETARY_SUPPLEMENT: Omega-3 fatty acid supplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effectiveness of Polymyxin B Sulphate + Prednisolone + Benzocaine + Clioquinol in Acute and Sub-acute Dermatitis Eczematous
Status: COMPLETED
Conditions: Eczema
Interventions: DRUG: polymyxin B sulphate + prednisolone + benzocaine + clioquinol|DRUG: betamethasone + gentamicin + tolnaftato + cleoquinol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Selenium and Prostate Cancer: Clinical Trial on Availability to Prostate Tissue and Effects on Gene Expression
Status: COMPLETED
Conditions: Prostatic Neoplasms|Prostate Cancer
Interventions: DIETARY_SUPPLEMENT: Selenium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Colchicine and Nonsteroidal Anti-inflammatory Drug Combination Therapy and Renal Function in Gout Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Renal Impairment|Gout|Colchicine Adverse Reaction|Nonsteroidals (NSAIDs)Toxicity
Interventions: DRUG: Colchicine and NSAID
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Nu-Mask Intraoral Airway Device Versus Conventional Bag Valve Mask Ventilation Crossover Trial
Status: COMPLETED
Conditions: Apnea
Interventions: DEVICE: NuMask Intraoral Airway Device|DEVICE: Bag Valve Mask
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Effect of OXYJUN on Ejection Fraction and Markers of Cardiovascular Injury
Status: COMPLETED
Conditions: Cardiac Function in Young Athletes
Interventions: DIETARY_SUPPLEMENT: E-OJ-01 (OXYJUN)|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: COVID-19-associated ARDS Treated With Dexamethasone: Alliance Covid-19 Brasil III
Status: TERMINATED
Conditions: Coronavirus Infection|Pneumonia, Viral|Acute Respiratory Distress Syndrome
Interventions: DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective, Non-Blinded, Randomized Controlled Trial on Early Administration of Pulmonary Surfactant Guided by Lung Ultrasound Scores in Very Preterm Infants.
Status: NOT_YET_RECRUITING
Conditions: Early Administration of Pulmonary Surfactant Guided by Lung Ultrasound Scores in Very Preterm Infants
Interventions: OTHER: PS was given according to lung ultrasound score|OTHER: PS was given according to clinical criteria
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nasal Suction in Infants With Bronchiolitis Using a NoseFrida vs. Bulb Syringe
Status: TERMINATED
Conditions: Bronchiolitis|Respiratory Disease
Interventions: DEVICE: Nose Frida nasal suction device|DEVICE: Bulb syringe nasal suction device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EHR-integrated rUTI Texting Platform
Status: RECRUITING
Conditions: Recurrent Urinary Tract Infection
Interventions: DEVICE: EHR-integrated texting platform (Urotrust)|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Efficacy of Therapies for Metastatic Castration-resistant Prostate Cancer (mCRPC)
Status: TERMINATED
Conditions: Metastatic Castration-resistant Prostate Cancer
Interventions: DRUG: Acapatamab|DRUG: Enzalutamide|DRUG: Abiraterone|DRUG: AMG 404
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MAGNOLIA: Extension Study of Patients With Non-infectious Uveitis Who Participated in CLS1001-301
Status: COMPLETED
Conditions: Uveitis|Uveitis, Posterior|Uveitis, Anterior|Uveitis, Intermediate|Panuveitis
Interventions: DRUG: 4 mg CLS-TA Suprachoriodal Injection|DRUG: Sham procedure
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Rejuvant™ Safety and Biomarker Study
Status: COMPLETED
Conditions: Aging Well
Interventions: DIETARY_SUPPLEMENT: Rejuvant|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Mesenchymal Stromal Cells for the Treatment of SARS-CoV-2 Induced Acute Respiratory Failure (COVID-19 Disease)
Status: COMPLETED
Conditions: Sars-CoV2|Acute Respiratory Distress Syndrome|COVID-19
Interventions: BIOLOGICAL: Mesenchymal Stromal Cells|OTHER: Supportive Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: COVID-19 and Disease Progression to the Severe Form: A Study on the Use of Monoclonal Antibodies Against SARS-CoV-2
Status: UNKNOWN
Conditions: COVID-19
Interventions: DRUG: Bamlanivimab|DRUG: Bamlanivimab and Etesevimab Drug Combination|DRUG: Casirivimab and Imdevimab Drug Combination|DRUG: Sotrovimab
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Application of the Visualization of Treatment Objective (VTO) Analyses in Fabricating Anterior Repositioning Splints
Status: UNKNOWN
Conditions: Temporomandibular Joint Disorders
Interventions: PROCEDURE: therapeutic position of the anterior repositioning splints
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Safety, Tolerability, and Pharmacodynamics of JNJ-54175446 in Participants With Major Depressive Disorder
Status: COMPLETED
Conditions: Depressive Disorder, Major
Interventions: DRUG: JNJ-54175446, 600 mg|DRUG: JNJ-54175446, 150 mg|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: NK White Blood Cells and Interleukin in Children and Young Adults With Advanced Solid Tumors
Status: COMPLETED
Conditions: Solid Tumors|Brain Tumors|Sarcoma|Pediatric Cancers|Neuroblastoma
Interventions: BIOLOGICAL: Recombinant human interleukin-15 (rhIL-15)|BIOLOGICAL: NK Cell Infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT