pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Evaluation of Effectiveness and Safety of Belotero Balance® (+) Lidocaine for Volume Augmentation of the Infraorbital Hollow
Status: COMPLETED
Conditions: Volume Loss in the Infraorbital Hollow Area
Interventions: DEVICE: Belotero Balance (+) Lidocaine, needle|DEVICE: Belotero Balance (+) Lidocaine, cannula|DEVICE: Untreated-control / delayed-treatment, needle|DEVICE: Untreated-control / delayed-treatment, cannulas
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Surufatinib in Advanced Hepatocellular Carcinoma Based on Single-cell Sequencing of Tumor Samples
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Surufatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Impact of MS-20 on Gut Microbiota Composition in Adult Individuals
Status: COMPLETED
Conditions: Microbiota
Interventions: DRUG: MS-20|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Sodium Nitrate on Blood Flow in Becker Muscular Dystrophy
Status: COMPLETED
Conditions: Becker Muscular Dystrophy
Interventions: DIETARY_SUPPLEMENT: Sodium Nitrate|DIETARY_SUPPLEMENT: Sodium Nitrate - double dose|DIETARY_SUPPLEMENT: Placebo|PROCEDURE: Increased exercise intensity
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study to Assess the Safety, Tolerability, Pharmacodynamics and Pharmacokinetics of ASP6981 in Subjects With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: ASP6981|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Remdesivir and Tociluzumab for the Management of Severe COVID-19: A Randomized Controlled Trial
Status: COMPLETED
Conditions: Covid19|Covid-19 ARDS
Interventions: DRUG: Remdesivir|DRUG: Tocilizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Motor System Activation With Transcranial Direct Current Stimulation and Physical Exercise to Reduce Pain in Elderly
Status: RECRUITING
Conditions: Chronic Pain
Interventions: OTHER: transcranial direct current stimulation|OTHER: Physical exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Expected Advantage of Administering Prophylactic Antibiotics Using Target- Concentration Controlled Infusion
Status: RECRUITING
Conditions: Anti-bacterial Agents|Pharmacokinetics|General Surgery
Interventions: PROCEDURE: target-controlled infusion (one of the administration methods)|PROCEDURE: Standard administration method
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of PF-06473871 to Reduce Hypertrophic Scars From Recurring Post-Revision Surgery
Status: COMPLETED
Conditions: Reduction of Hypertrophic Skin Scarring
Interventions: DRUG: PF-06473871|DRUG: PF-06473871
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Trial to Compare NNC0123-0000-0338 in a Tablet Formulation and Insulin Glargine in Subjects With Type 2 Diabetes Currently Treated With Oral Antidiabetic Therapy
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: insulin 338 (GIPET I)|DRUG: insulin glargine|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dynamic Monitoring of ctDNA Methylation to Predict Relapse in Colorectal Cancer After Radical Resection (POSTCA)
Status: RECRUITING
Conditions: Colorectal Cancer|Circulating Tumor DNA|Surveillance|Methylation
Interventions: DIAGNOSTIC_TEST: Multigene methylation detection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Prophylactic Cranial Irradiation (PCI) for Small Cell Carcinoma of the Urothelium
Status: ACTIVE_NOT_RECRUITING
Conditions: Bladder Cancer
Interventions: RADIATION: Prophylactic Cranial Irradiation (PCI)|OTHER: Brain X-ray
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Intravitreal Anti-VEGF on Retinal Vessels Diameter
Status: UNKNOWN
Conditions: Age Related Macular Degeneration
Interventions: DRUG: Intravitreal Ranibizumab|DRUG: Intravitreal bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose:
Clinical trial: Evaluation of White Sweet Potato Tube Feeding Formula on Type 2 Diabetic Residents in Long-term Care Institutions
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DIETARY_SUPPLEMENT: Commercial diabetic formula|DIETARY_SUPPLEMENT: White sweet potato formula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy of Travoprost/Timolol BAC-free
Status: COMPLETED
Conditions: Open-Angle Glaucoma|Ocular Hypertension
Interventions: DRUG: Travoprost 0.004%/Timolol 0.5% BAC-free ophthalmic solution|DRUG: Travoprost 0.004%/Timolol 0.5% ophthalmic solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: KX2-391 in Treating Patients With Advanced Solid Tumors or Lymphoma That Did Not Respond to Treatment
Status: COMPLETED
Conditions: Lymphoma|Lymphoproliferative Disorder|Small Intestine Cancer|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: Src kinase inhibitor KX2-391|OTHER: immunoenzyme technique|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testing Lutetium Lu 177 Dotatate in Patients With Somatostatin Receptor Positive Advanced Bronchial Neuroendocrine Tumors
Status: RECRUITING
Conditions: Advanced Lung Neuroendocrine Tumor|Functioning Lung Neuroendocrine Tumor|Locally Advanced Lung Neuroendocrine Neoplasm|Lung Neuroendocrine Neoplasm|Lung Neuroendocrine Tumor G1|Lung Neuroendocrine Tumor G2|Metastatic Lung Neuroendocrine Neoplasm|Metastatic Lung Neuroendocrine Tumor|Non-Functioning Lung Neuroendocrine Tumor|Recurrent Lung Neuroendocrine Neoplasm|Unresectable Lung Neuroendocrine Neoplasm|Unresectable Lung Neuroendocrine Tumor
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|DRUG: Everolimus|OTHER: Fludeoxyglucose F-18|DRUG: Lutetium Lu 177 Dotatate|PROCEDURE: Positron Emission Tomography|PROCEDURE: Single Photon Emission Computed Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Therapy BRIDGE (Bringing Real-Time Instruction Via Developmental and Gestationally-appropriate Education/Coaching) Program: A Pilot Study
Status: RECRUITING
Conditions: Intraventricular Hemorrhage
Interventions: OTHER: Therapy BRIDGE Program
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Ibandronate (Bondronat) in Participants With Malignant Bone Disease
Status: COMPLETED
Conditions: Pain; Bone Neoplasms; Neoplasm Metastasis
Interventions: DRUG: Ibandronate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acute Health Effects of Traffic-Related Air Pollution Exposure
Status: UNKNOWN
Conditions: Cardiovascular System|Respiratory System
Interventions: BEHAVIORAL: Walking along a busy road|BEHAVIORAL: Walking in a traffic-free park
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Lateralization of the Inferior Alveolar Nerve After Repositioning of the Bone Window Versus Sticky Bone Augmentation
Status: COMPLETED
Conditions: Posterior Atrophic Mandible|Inferior Alveolar Nerve|Nerve Lateralization
Interventions: PROCEDURE: Guided inferior Alveolar Nerve lateralization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long-Term Effects of Sublingual Grass Therapy
Status: COMPLETED
Conditions: Rhinitis, Allergic, Seasonal
Interventions: BIOLOGICAL: Sublingual immunotherapy (SLIT)|BIOLOGICAL: Subcutaneous immunotherapy (SCIT)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Peri-operative Sintilimab in Combination With SOX in Locally Advanced Gastric Cancer
Status: UNKNOWN
Conditions: Gastric Cancer|Perioperative|Sintilimab
Interventions: DRUG: Sintilimab|DRUG: S-1|DRUG: Oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testing Palbociclib (PD-0332991) as Potentially Targeting Treatment in Cancers With CDK4 or CDK6 Amplification (MATCH - Subprotocol Z1C)
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Lymphoma|Advanced Malignant Solid Neoplasm|Refractory Lymphoma|Refractory Malignant Solid Neoplasm
Interventions: PROCEDURE: Biopsy|PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|PROCEDURE: Magnetic Resonance Imaging|DRUG: Palbociclib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Post-operative Emesis and Pain Outcomes After Cesarean Delivery
Status: ACTIVE_NOT_RECRUITING
Conditions: Pain, Postoperative|Cesarean Section|Nausea, Postoperative|Vomiting, Postoperative
Interventions: PROCEDURE: Mechanical Temporal Summation assessment|OTHER: Preoperative pain assessment|OTHER: Questionnaires|OTHER: Headspace
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of SHR-1701 Plus Platinum-containing Chemotherapy With or Without BP102 (Bevacizumab) as First-line Treatment in Cervical Cancer
Status: RECRUITING
Conditions: Cervical Cancer
Interventions: DRUG: SHR-1701 + paclitaxel + cisplatin/carboplatin + BP102|DRUG: SHR-1701 + paclitaxel + cisplatin/carboplatin± BP102|DRUG: Placebo + paclitaxel + cisplatin/carboplatin ± BP102
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective Clinical Study Evaluating Tibiofemoral Rotational Alignment Using Intraoperative Sensing During Total Knee Arthroplasty (TKA)
Status: TERMINATED
Conditions: Osteoarthritis
Interventions: DEVICE: TKA with "Verasense"|PROCEDURE: TKA without "Verasense"
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Optimum Immunosuppression in Renal Transplant Recipients.New Onset Diabetes After Transplantation
Status: TERMINATED
Conditions: Diabetes Mellitus, Adult-Onset
Interventions: DRUG: Tacrolimus with rapid steroid withdrawal|DRUG: Tacrolimus with steroids minimization|DRUG: CsA with steroid minimization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Prone Position in Patients on High-flow Nasal Oxygen Therapy for COVID-19 (HIGH-PRONE-COVID-19)
Status: COMPLETED
Conditions: Acute Respiratory Distress Syndrome|COVID-19
Interventions: OTHER: Prone decubitus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Safety and Efficacy of ON101 Cream for the Treatment of Chronic Diabetic Foot Ulcers
Status: UNKNOWN
Conditions: Chronic Diabetic Foot Ulcers
Interventions: DRUG: ON101 Cream|OTHER: Vehicle Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Evaluation of SMART Camera Treatment Presets for Cutaneous Lesions Using IPL
Status: COMPLETED
Conditions: Vascular Lesion|Pigmented Lesions
Interventions: DEVICE: IPL with smart diagnostic handpiece
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Role of Mosapride in Patients With Gastroesophageal Reflux Disease
Status: COMPLETED
Conditions: Gastroesophageal Reflux Disease
Interventions: DRUG: mosapride for the first month and placebo for the 2nd month|DRUG: placebo for the first and mosapride for the second month
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: High Flow Nasal Cannula Versus Non-Invasive (NIV)in Both Hypoxemic and Hypercapnic Respiratory Failure.
Status: NOT_YET_RECRUITING
Conditions: Acute Hypoxemic Respiratory Failure|Acute Hypercapnic Respiratory Failure
Interventions: DEVICE: High flow nasal cannula (HFNC)|DEVICE: Non-Invasive Mechanical Ventilation (NIV)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Assess a New Barrier Film's Ability to Provide Skin Protection Against Incontinence & Allow Healing
Status: TERMINATED
Conditions: Incontinence Associated Dermatitis
Interventions: DEVICE: Cavilon Advanced Skin Protectant|DEVICE: ConvaTec Sensi-Care Protective Barrier
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Regorafenib, Ipilimumab and Nivolumab for the Treatment of Chemotherapy Resistant Microsatellite Stable Metastatic Colorectal Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Colon Adenocarcinoma|Metastatic Colon Adenocarcinoma|Metastatic Colorectal Adenocarcinoma|Metastatic Colorectal Carcinoma|Metastatic Rectal Adenocarcinoma|Stage III Colon Cancer AJCC v8|Stage III Rectal Cancer AJCC v8|Stage IIIA Colon Cancer AJCC v8|Stage IIIA Rectal Cancer AJCC v8|Stage IIIB Colon Cancer AJCC v8|Stage IIIB Rectal Cancer AJCC v8|Stage IIIC Colon Cancer AJCC v8|Stage IIIC Rectal Cancer AJCC v8|Stage IV Colon Cancer AJCC v8|Stage IV Colorectal Cancer AJCC v8|Stage IV Rectal Cancer AJCC v8|Stage IVA Colon Cancer AJCC v8|Stage IVA Colorectal Cancer AJCC v8|Stage IVA Rectal Cancer AJCC v8|Stage IVB Colon Cancer AJCC v8|Stage IVB Colorectal Cancer AJCC v8|Stage IVB Rectal Cancer AJCC v8|Stage IVC Colon Cancer AJCC v8|Stage IVC Colorectal Cancer AJCC v8|Stage IVC Rectal Cancer AJCC v8
Interventions: BIOLOGICAL: Ipilimumab|BIOLOGICAL: Nivolumab|DRUG: Regorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of BL-B01D1 in Patients With Multiple Solid Tumors, Including Locally Advanced or Metastatic Urinary System Tumors
Status: RECRUITING
Conditions: Urinary System Tumor|Solid Tumor
Interventions: DRUG: BL-B01D1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diffuse Diabetic Maculopathy With Intravitreal Triamcinolone or Laser
Status: COMPLETED
Conditions: Macular Edema
Interventions: DRUG: intravitreous triamcinolone|PROCEDURE: laser therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of the ISS Sleeve Augmentation Technique in the Treatment of Thoracolumbar Osteopenic Fractures
Status: TERMINATED
Conditions: Osteoporotic Fracture of Vertebra
Interventions: DEVICE: Augmentation with the ISS Study System|OTHER: Augmentation with PMMA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effectiveness of Kegal Exercises on Urinary Incontinence Impact in Geriatric Incontinence
Status: COMPLETED
Conditions: Urinary Incontinence in Geriatric Population
Interventions: BEHAVIORAL: Kegel Exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Comparison Between Everolimus-eluting Stent (EES) and Sirolimus-eluting Stent (SES) in the Bifurcation Lesion
Status: UNKNOWN
Conditions: Ischemic Heart Disease
Interventions: PROCEDURE: kissing balloon inflation|DEVICE: EES vs. SES
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Short-term, Long-term and Cost-effectiveness of Treating Depression and Anxiety Disorders in Children and Adolescents
Status: UNKNOWN
Conditions: Depression, Anxiety
Interventions: BEHAVIORAL: psychodynamic psychotherapy|BEHAVIORAL: cognitive behavioral psychotherapy|BEHAVIORAL: psychodynamic family intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effect of Different Cleaning and Disinfection Procedures on the Involvement of Candida Species
Status: COMPLETED
Conditions: Candidiasis, Oral
Interventions: OTHER: glutaraldehyde disinfection and microwave application|OTHER: Chlorhexidine gluconate disinfection and microwave application|OTHER: Sodium hypochlorite disinfection and microwave application|OTHER: glutaraldehyde disinfection and ozone therapy|OTHER: Chlorhexidine gluconate disinfection and ozone therapy|OTHER: Sodium hypochlorite disinfection and ozone therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Multicomponent Exercises VIVIFRAIL® in Older Adults
Status: RECRUITING
Conditions: Frailty|Aging|Physical Disability
Interventions: OTHER: Intervention group (ViviFrail)|OTHER: Group Suggestions for a Healthy Life (CG)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of NK012 and 5-FU/LV in Solid Tumors Followed by Dose Expansion in Colorectal Cancer
Status: COMPLETED
Conditions: Advanced Solid Tumors|Metastatic Colorectal Cancer
Interventions: DRUG: NK012 and 5-FU
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Neoadjuvant Myocet®, Paclitaxel, Pertuzumab, and Trastuzumab in HER2-positive Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Liposomal Doxorubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I and Pharmacology Study of Camptothecin-20-O-Propionate Hydrate (CZ48) in Patients With Solid Tumors or Lymphoma
Status: COMPLETED
Conditions: Advanced Solid Tumors|Lymphomas
Interventions: DRUG: Camptothecin-20-O-Propionate Hydrate (CZ48)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Omentectomy for the Treatment of Diabetes Mellitus Type 2
Status: COMPLETED
Conditions: Diabetes Mellitus Type 2|Dyslipidemia|Hypercholesterolemia|Obesity
Interventions: PROCEDURE: removal of omentum
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevention Of Primary Foot Ulcers in High-risk Diabetes Patients
Status: UNKNOWN
Conditions: Diabetes Mellitus|Foot Ulcer, Diabetic|Primary Prevention
Interventions: DEVICE: 3D printed insoles for normal footware
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A COVID-19 Study to Evaluate Safety and Pharmacokinetics of COVID-HIGIV Administered in Healthy Adults
Status: COMPLETED
Conditions: COVID-19
Interventions: BIOLOGICAL: COVID-HIGIV|OTHER: Placebo (saline)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Angiotensin Receptor-Neprilysin Inhibition on Cardiac Fibrosis in Patients With HFpEF
Status: UNKNOWN
Conditions: Heart Failure With Preserved Ejection Fraction
Interventions: DRUG: Angiotensin Receptor-Neprilysin Inhibition|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Femur Fracture: Functional Bracing vs. Hip Spica Cast
Status: ACTIVE_NOT_RECRUITING
Conditions: Pediatric Femur Fracture
Interventions: DEVICE: Functional Brace|DEVICE: Hip Spica Cast
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Subcutaneous Daratumumab, Once Weekly Carfilzomib, and Dexamethasone (DKd) in Patients With High-Risk Smoldering Multiple Myeloma
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: Dexamethasone|DRUG: Carfilzomib|BIOLOGICAL: Daratumumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Safety and Immunogenicity of Meningococcal B and Meningococcal ACWY Vaccine in at Risk Population
Status: UNKNOWN
Conditions: Hiv|Meningitis, Meningococcal|HIV Infections
Interventions: BIOLOGICAL: Bexsero® (meningitis B vaccine)|BIOLOGICAL: Menveo® (meningitis ACWY vaccine)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Buprenorphine's Dose Response Curve
Status: COMPLETED
Conditions: Opioid-related Disorders
Interventions: DRUG: Buprenorphine|DRUG: Morphine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Spinal Cord Associative Plasticity Study
Status: RECRUITING
Conditions: Cervical Spinal Cord Injury|Tetraplegia/Tetraparesis|Cervical Myelopathy
Interventions: PROCEDURE: Non-invasive pairing of cortical and spinal stimulation|PROCEDURE: Intraoperative pairing of cortical and spinal stimulation|PROCEDURE: Non-invasive repeated pairing of cortical and spinal stimulation (SCAP)|PROCEDURE: Intraoperative repeated pairing of cortical and spinal stimulation (SCAP)|PROCEDURE: Intraoperative repeated pairing of cortical and spinal stimulation (SCAP) at or below myelopathic region
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Self-management and HeAlth Promotion in Early-stage Dementia With E-learning for Carers
Status: UNKNOWN
Conditions: Dementia
Interventions: BEHAVIORAL: SHAPE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Incentive Spirometry and Breath Stacking
Status: UNKNOWN
Conditions: Postoperative Complications
Interventions: DEVICE: Incentive spirometry (IS)|DEVICE: Breath Stacking (BS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Electroencephalography Based Neurofeedback in Chronic Neuropathic Pain
Status: UNKNOWN
Conditions: Neuropathic Pain
Interventions: DEVICE: TMS|OTHER: Neurofeedback|OTHER: Sham neurofeedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study of Tumor Samples in Patients Undergoing Radiation Therapy or Surgery For Primary Melanoma of the Eye
Status: COMPLETED
Conditions: Intraocular Melanoma
Interventions: GENETIC: fluorescence in situ hybridization|OTHER: laboratory biomarker analysis|PROCEDURE: fine-needle aspiration|PROCEDURE: therapeutic conventional surgery|OTHER: Questionnaires
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: SPSIPB vs SAPB for Thoracoscopic Surgery
Status: NOT_YET_RECRUITING
Conditions: Lung Diseases|Lung Cancer|Lung Neoplasms|Lung Cancer Metastatic|Thoracic Diseases|Thoracic Cancer|Thoracic Neoplasms
Interventions: DRUG: SPSIPB blcok|DRUG: SAPB block|DRUG: Postoperative analgesia management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy & Safety Study of Once-weekly Oral Aripiprazole in Children and Adolescents With Tourette's Disorder
Status: COMPLETED
Conditions: Tourette's Disorder
Interventions: DRUG: Aripiprazole|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phenotyping and Classifying Asthma Exacerbations
Status: RECRUITING
Conditions: Asthma Attack
Interventions: BEHAVIORAL: Questionnaires|DEVICE: Spirometry|DEVICE: Fractional Exhaled Nitric Oxide (FeNO)|DEVICE: Corsano watch|DEVICE: e-Nose|PROCEDURE: Nasopharyngeal swabs and nasal lining fluid|DEVICE: Sputum culture|PROCEDURE: Blood sample
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Retrospective Study of Patients Who Were Treated With Fondaparinux Pre-, Peri- and/or Postpartum for Prophylaxis or Treatment of Venous Thromboembolism
Status: COMPLETED
Conditions: Thromboembolism|Venous Thromboembolism
Interventions: DRUG: fondaparinux
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study to Evaluate the Efficacy of Poppi Apple Cider Vinegar Prebiotic Soda to Improve Gut Health In Participants
Status: COMPLETED
Conditions: IBS - Irritable Bowel Syndrome
Interventions: DIETARY_SUPPLEMENT: Drink Poppi Soda
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Melatonin as Adjuvant Treatment for ADHD in Adults
Status: UNKNOWN
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: DRUG: Melatonin 5 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of Mifepristone in Combat Veterans With Posttraumatic Stress Disorder
Status: UNKNOWN
Conditions: Posttraumatic Stress Disorder
Interventions: DRUG: mifepristone|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Study of Capecitabine and Oxaliplatin in Combination With Radiotherapy in Patients With Unresectable Gastro-Intestinal Cancer
Status: COMPLETED
Conditions: Stomach Cancer|Gall Bladder Cancer|Bile Ductus Cancer|Pancreas Cancer|Colorectal Cancer
Interventions: OTHER: oxaliplatin, capecitabine, radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study for Zoledronic Acid to Prevent Bone Loss After Bariatric Surgery
Status: COMPLETED
Conditions: Bariatric Surgery Candidate
Interventions: DRUG: Zoledronic Acid|DIETARY_SUPPLEMENT: Calcium citrate + vitamin D|DIETARY_SUPPLEMENT: Vitamin D3
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Early Cycle Ergometry for Critically-Ill Liver Failure Patients in a Transplant Intensive Care Unit
Status: TERMINATED
Conditions: Liver Cirrhoses|Liver Failure|ICU Acquired Weakness
Interventions: DEVICE: Cycle ergometry
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Imaging Technology, Contrast-Enhanced Mammography, in Predicting Breast Cancer
Status: RECRUITING
Conditions: Breast Carcinoma
Interventions: PROCEDURE: Biopsy|PROCEDURE: Contrast-Enhanced Mammography|OTHER: Questionnaire Administration|OTHER: Radioactive Iodine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Randomized Trial of Antithymocyte Globulin Versus Cyclosporine to Treat the Cytopenia of Myelodysplastic Syndrome
Status: COMPLETED
Conditions: Hematologic Diseases|Myelodysplastic Syndromes
Interventions: DRUG: Antithymocyte globulin|DRUG: Cyclosporine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Efficacy of Exercise on Post Needling Soreness
Status: COMPLETED
Conditions: Post Needling Soreness|Myofascial Pain|Myofascial Pain Syndrome|Myofascial Trigger Point Pain
Interventions: OTHER: Eccentric exercise|OTHER: Concentric exercise.|OTHER: Isometric exercise.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficiency of Intraoperative Optical Coherence Tomography (iOCT)
Status: UNKNOWN
Conditions: Epiretinal Membrane|Glaucoma|Cornea
Interventions: DEVICE: Intraoperative Optical Coherence Tomography (iOCT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Radiosurgery for Patients With Oligometastatic Disease at Initial Presentation
Status: TERMINATED
Conditions: Oligometastatic Disease
Interventions: RADIATION: Stereotactic Radiosurgery (SRS)|DRUG: Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Identification of the Sensory Level Block to Cold During Epidural Analgesia for Labor: A Cohort Study to Determine the Influence of the Direction of Testing
Status: COMPLETED
Conditions: Labor Pain
Interventions: DIAGNOSTIC_TEST: Sensory block level check using ice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study Called SMART-Finder to Look for People With Increased Amounts of Albumin in the Urine (UACR Level) in a Group of Type 2 Diabetes Mellitus Patients
Status: RECRUITING
Conditions: Type 2 Diabetes Mellitus|Chronic Kidney Disease
Interventions: DRUG: Finerenone (Kerendia, BAY94-8862)|DRUG: Type 2 DM drugs
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase I/IIa Clinical Trial to Assess Feasibility, Safety and Antitumor Activity of Autologous SLAMF7 CAR-T Cells in Multiple Myeloma
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: SLAMF7 CAR-T
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tourniquet vs. Short Time Tourniquet in Primary Robotic Assisted TKA
Status: COMPLETED
Conditions: Knee Arthropathy
Interventions: OTHER: Primary Robotic-Assisted Total Knee Arthroplasty with a short tourniquet time|OTHER: Primary Robotic-Assisted Total Knee Arthroplasty with the use of a tourniquet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Clinical Study of SI-B001 in Combination With Paclitaxel in the Treatment of Recurrent and Metastatic HNSCC
Status: RECRUITING
Conditions: Head and Neck Squamous Cell Carcinoma
Interventions: DRUG: SI-B001|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pulsed Dose Chemotherapy Plus Pembrolizumab in Recurrent/Metastatic HNSCC
Status: RECRUITING
Conditions: Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma (R/M HNSCC)
Interventions: DRUG: Pembrolizumab|DRUG: Carboplatin|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preventing Stem Cell Transplant Complications With a Blood Separator Machine
Status: COMPLETED
Conditions: MDS (Myelodysplastic Syndrome)|Myeloproliferative Disorder|Lymphoma, Non-Hodgkin|ALL (Acute B-Lymphoblastic Leukemia)|AML (Acute Myelogenous Leukemia
Interventions: DEVICE: Graft Manipulation (CD34+ Selection)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Topical Sulforaphane on Skin Fragility Seen in Skin Aging and With Ultraviolet Exposure
Status: TERMINATED
Conditions: Aging
Interventions: DRUG: Sulforaphane|RADIATION: Narrow-band Ultraviolet B exposure|PROCEDURE: 4 mm skin punch biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Effect of Intensive Insulin Therapy
Status: COMPLETED
Conditions: the Maintenance of Normoglycemia|the Incidence of Ventilator Associated Pneumonia (VAP)|Treatment Period in the Intensive Care Unit
Interventions: PROCEDURE: glucontrol (insulin therapy)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Development and Assessment of a Teacher-led Intervention in Preventing Tobacco Use Among the Youth in Ghana
Status: UNKNOWN
Conditions: Smoking Reduction|Smoking Cessation|Smoking, Tobacco|Smoking Behaviors
Interventions: OTHER: Health education lessons (Smart-Kid's program)|OTHER: School Health and Education Program (SHEP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Association Between Lumbar Muscle Atrophy, Sagittal Pelvic Alignment and Stenosis Grade in Patients With Degenerative Lumbar Spinal Stenosis
Status: COMPLETED
Conditions: Lumbar Spinal Stenosis (LSS)
Interventions: OTHER: radiographic data collection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Chondroitin Sulphate Treatment Efficacy in Rhizarthrosis.
Status: UNKNOWN
Conditions: Rhizarthrosis
Interventions: DRUG: Chondroitin sulfate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Reducing Operative and Post-operative Morbidity in Living Kidney Donors With the Airseal System
Status: COMPLETED
Conditions: Pain
Interventions: DEVICE: Valveless recirculating insufflation (VTI)|DEVICE: Conventional pressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Early TIPS for Ascites Study
Status: TERMINATED
Conditions: Liver Cirrhosis|Portal Hypertension|Ascites
Interventions: DEVICE: TIPS procedure with the GORE® VIATORR® TIPS Endoprosthesis|PROCEDURE: LVP|DEVICE: TIPS procedure with the GORE® VIATORR® TIPS Endoprosthesis for subjects who failed LVP and crossed over to TIPS per protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Trial of Ipilimumab and Nivolumab in Nasopharyngeal Carcinoma
Status: RECRUITING
Conditions: Nasopharyngeal Carcinoma
Interventions: DRUG: Ipilimumab|DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: IPX056 in Subjects With Established Spasticity Resulting From Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DRUG: IPX056 20 mg|DRUG: IPX056 40 mg|DRUG: Encapsulated Baclofen 20 mg|DRUG: Placebo Baclofen Tablet|DRUG: IPX056 10 mg|DRUG: IPX056 30 mg|DRUG: IPX056 35 mg|DRUG: Placebo IPX056 20 mg|DRUG: Placebo IPX056 40 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of the Wound Healing Efficacy and Tolerance of a Medical Device on Wounds in Healthy Subjects.
Status: COMPLETED
Conditions: Healthy
Interventions: PROCEDURE: Induction of suction blister|OTHER: Transepidermal water loss (TEWL)|OTHER: Macrophotography|DEVICE: Wound healing medical device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety of Rt-PA + Transcranial Emission of Low-Energy Lasers for Acute Stroke Recovery
Status: TERMINATED
Conditions: Ischemic Stroke
Interventions: DEVICE: Transcranial Laser Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Different Simulation Methods Used in Adult Basic Life Support Training
Status: ENROLLING_BY_INVITATION
Conditions: First Aid
Interventions: BEHAVIORAL: Providing BLS and AED trainings given by the Ministry of Health with Low Realism Simulation.|BEHAVIORAL: Providing BLS and AED trainings given by the Ministry of Health with High Reality Simulation|BEHAVIORAL: Providing BLS and AED trainings given by the Ministry of Health with Virtual Reality
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Comparing Study Between ALT02(Trastuzumab Biosimilar) and Herceptin® in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: BIOLOGICAL: ALT02|BIOLOGICAL: EU-licensed Herceptin|BIOLOGICAL: US-licensed Herceptin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Busulfan and Fludarabine Followed by Post-transplant Cyclophosphamide
Status: COMPLETED
Conditions: Hematologic Diseases|Leukemia|Lymphoma|Myeloma
Interventions: DRUG: Busulfan|DRUG: Fludarabine|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multiple Ascending Dose Tolerability, Pharmacokinetic and Pharmacodynamic Study of DG3173
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: DG3173|DRUG: DG3173+Octreotide|DRUG: Octreotide|DRUG: DG3173 Placebo|DRUG: DG3173 Placebo+Octreotide Placebo|DRUG: Octreotide+DG3173 Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evolutionary Therapy for Rhabdomyosarcoma
Status: RECRUITING
Conditions: Rhabdomyosarcoma
Interventions: DRUG: Vincristine|DRUG: Cyclophosphamide|DRUG: Vinorelbine|DRUG: Actinomycin D|DRUG: Cyclophosphamide Pill
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pembrolizumab + Capecitabine／Oxaliplatin (CapeOx) -HER2 Nagative and Pembrolizumab + Trastuzumab + Cisplatin/Capecitabine HER2 Positive
Status: ACTIVE_NOT_RECRUITING
Conditions: Gastric Cancer
Interventions: DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Xylitol BSI Multisite - Reduction of Bloodstream Infections From Oral Organisms in Pediatric Stem Cell Transplant
Status: RECRUITING
Conditions: Allogeneic Stem Cell Transplantation
Interventions: OTHER: Xylitol|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Research Study to Investigate How Well NNC0165-1875 in Combination With Semaglutide Works in People With Obesity
Status: COMPLETED
Conditions: Obesity
Interventions: DRUG: Semaglutide 2.4 mg and NNC0165-1875 2.0 mg|DRUG: Semaglutide 2.4 mg and placebo 2.0 mg|DRUG: Semaglutide 2.4 mg and NNC0165-1875 1.0 mg|DRUG: Semaglutide 2.4 mg and placebo 1.0 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sitaxsentan Efficacy And Safety Trial With A Randomized Prospective Assessment Of Adding Sildenafil (SR-PAAS)
Status: TERMINATED
Conditions: Pulmonary Arterial Hypertension|Pulmonary Hypertension
Interventions: DRUG: Sitaxsentan|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bortezomib Plus Rituximab for EBV+ PTLD
Status: COMPLETED
Conditions: Post-transplant Lymphoproliferative Disease|Solid Organ Transplant|Stem Cell Transplant (Bone Marrow Transplant)|Epstein Barr Virus Infections
Interventions: DRUG: bortezomib|DRUG: rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy, Safety and Immunogenicity Study of Inactivated SARS-CoV-2 Vaccine for Preventing Against COVID-19
Status: UNKNOWN
Conditions: COVID-19
Interventions: BIOLOGICAL: Inactivated SARS-CoV-2 Vaccine (Vero cell)|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Educating Women About Pelvic Floor Disorders During Pregnancy
Status: COMPLETED
Conditions: Pelvic Floor Disorders|Stress Urinary Incontinence|Pelvic Organ Prolapse
Interventions: OTHER: Written Handouts|OTHER: Interactive Workshop
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Glutamate and Diastolic Function in Patients Undergoing Aortic Valve Repair
Status: COMPLETED
Conditions: Hypertrophy, Left Ventricular|Aortic Stenosis|Myocardial Ischemia|Cardiopulmonary Bypass
Interventions: DRUG: LG-group|DRUG: HG-group|DRUG: Placebo-group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: A Phase Ib Study to Evaluate the Safety, Efficacy, and Pharmacokinetics of Cibisatamab in Combination With Atezolizumab After Pretreatment With Obinutuzumab in Participants With Previously Treated Metastatic Colorectal Adenocarcinoma
Status: TERMINATED
Conditions: Colorectal Cancer
Interventions: DRUG: Obinutuzumab|DRUG: Atezolizumab|DRUG: Cibisatamab|DRUG: Tocilizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Amnio-Maxx in Patients With Diabetic Foot Ulcers Unresponsive to Standard of Care Treatment Alone
Status: NOT_YET_RECRUITING
Conditions: Diabetic Foot Ulcer
Interventions: OTHER: Amnio-Maxx
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Orally Administered Amcenestrant (SAR439859) in Japanese Postmenopausal Patients With Advanced Breast Cancer (AMEERA-2)
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Amcenestrant (SAR439859)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Quality and Effectiveness of a Personalised App to Support Patients With Fixed Braces
Status: NOT_YET_RECRUITING
Conditions: Treatment Adherence and Compliance
Interventions: OTHER: My Braces App
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Heparin Prophylaxis Dosing for Antepartum Hospitalizations (HEPDOSE)
Status: COMPLETED
Conditions: Pregnancy Related|Antepartum DVT
Interventions: DRUG: Standard Dose of Unfractionated Heparin|DRUG: Gestational Age-Based Dose of Unfractionated Heparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Two-channel Intravenous Patient-controlled Analgesia (IV-PCA) After Total Laparoscopic Hysterectomy (TLH)
Status: COMPLETED
Conditions: Total Laparoscopic Hysterectomy|Patient-controlled Analgesia
Interventions: OTHER: convetional PCA method unsing only 1-channel|OTHER: utilizing 2-channel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Study Assessing Potential Predictive Tumor Markers in Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: Panitumumab + FOLFOX (DP)|DRUG: Panitumumab + FOLFOX (no-DP)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Shamir Aspheric Ophthalmic Lenses (MyLens) for Myopic Control Clinical Trial
Status: TERMINATED
Conditions: Myopia
Interventions: DEVICE: Aspheric lens
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT