pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Outcomes of High-volume Saline Irrigation VS Povidone-Iodine Solution Cleaning of IOWI in Preventing SSIs in Emergency Laparotomies
Status: RECRUITING
Conditions: Surgical Site Infection|Surgical Wound|Surgical Incision|Emergency Laparotomies|Laparotomies|Post Operative Wound Infection|Wound Infection|Seroma
Interventions: PROCEDURE: 0.9% saline solution|PROCEDURE: Povidone-iodine Swab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Expressive Writing for Heart Healing
Status: COMPLETED
Conditions: Ischemic Heart Disease|Obesity
Interventions: BEHAVIORAL: Disease-related Expressive writing|BEHAVIORAL: Active Comparator: Traditional expressive writing|BEHAVIORAL: Sham Comparator: Neutral writing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Chest Compressor for Conservative Treatment of Pectus Carinatum: a Multicenter Study
Status: UNKNOWN
Conditions: Pectus Carinatum, Chondromanubrial
Interventions: DEVICE: Thoracic compressor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dexamethasone and Ondansetron Hydrochloride or Palonosetron Hydrochloride in Preventing Nausea and Vomiting in Patients Receiving Doxorubicin Hydrochloride and Cyclophosphamide For Early Stage Breast Cancer
Status: COMPLETED
Conditions: Male Breast Cancer|Nausea and Vomiting|Stage I Breast Cancer|Stage II Breast Cancer|Stage IIIA Breast Cancer
Interventions: DRUG: palonosetron hydrochloride|DRUG: cyclophosphamide|DRUG: dexamethasone|DRUG: doxorubicin hydrochloride|PROCEDURE: quality-of-life assessment|PROCEDURE: nausea and vomiting therapy|PROCEDURE: management of therapy complications|DRUG: ondansetron hydrochloride|OTHER: survey administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pazopanib in Combination With PCI-24781 in Patients With Metastatic Solid Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Solid Tumors
Interventions: DRUG: PZP115891, PCI-24781
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: DNA Changes That Affect Vitamin D Metabolism in Patients With Colorectal Cancer Receiving Vitamin D Supplements
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DIETARY_SUPPLEMENT: cholecalciferol|GENETIC: polymerase chain reaction|GENETIC: polymorphism analysis|GENETIC: protein expression analysis|GENETIC: reverse transcriptase-polymerase chain reaction|GENETIC: western blotting|OTHER: high performance liquid chromatography|OTHER: laboratory biomarker analysis|OTHER: pharmacological study|PROCEDURE: adjuvant therapy|PROCEDURE: immunoscintigraphy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Does Bupivacaine in Laparoscopic Portals Reduce Post Surgery Pain in Tubal Ligation by Electrocoagulation?
Status: UNKNOWN
Conditions: Pain
Interventions: DRUG: Saline solution (laparoscopic tubal ligation)|DRUG: Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dose-Escalation Study of TH-302 in Combination With Doxorubicin to Treat Patients With Advanced Soft Tissue Sarcoma
Status: COMPLETED
Conditions: Soft Tissue Sarcoma
Interventions: DRUG: TH-302
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effectiveness and Safety of EUS-guided Transluminal Drainage With 'Niti-S SPAXUS Stent'
Status: COMPLETED
Conditions: Pancreatic Pseudocyst
Interventions: DEVICE: Niti-S SPAXUS Stent
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Alterations in Intestinal Mucosal Barrier Visualized by Confocal Laser Endomicroscopy in Liver Cirrhosis: a Pilot Trial (AMBIC)
Status: TERMINATED
Conditions: Liver Cirrhoses
Interventions: DEVICE: Cellvisio 100 Series (fibered confocal microscopic system)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: DBT-SS for Cognitively Challenged Individuals With Deliberate Self-harm
Status: COMPLETED
Conditions: Self Harm|Suicide, Attempted|Borderline Personality Disorder
Interventions: BEHAVIORAL: Dialectic Behavior Therapy - Skills System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment Patterns and Bleeding Risk of Anticoagulants in Patients With Venous Thromboembolism in Korea
Status: COMPLETED
Conditions: Venous Thromboembolism
Interventions: DRUG: Parenteral anticoagulant|DRUG: Warfarin|DRUG: Apixaban|DRUG: Rivaroxaban|DRUG: Dabigatran|DRUG: Edoxaban
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: UCB Transplant of Inherited Metabolic Diseases With Administration of Intrathecal UCB Derived Oligodendrocyte-Like Cells
Status: RECRUITING
Conditions: Adrenoleukodystrophy|Batten Disease|Mucopolysaccharidosis II|Leukodystrophy, Globoid Cell|Leukodystrophy, Metachromatic|Neimann Pick Disease|Pelizaeus-Merzbacher Disease|Sandhoff Disease|Tay-Sachs Disease|Brain Diseases, Metabolic, Inborn|Alpha-Mannosidosis|Sanfilippo Mucopolysaccharidoses
Interventions: BIOLOGICAL: DUOC-01
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ph I/II Trial of Systemic VSV-IFNβ-NIS in Combination With Checkpoint Inhibitor Therapy in Patients With Select Solid Tumors
Status: RECRUITING
Conditions: Solid Tumor|Non Small Cell Lung Cancer|Neuroendocrine Carcinoma
Interventions: BIOLOGICAL: VSV-IFNβ-NIS|BIOLOGICAL: Pembrolizumab|BIOLOGICAL: ipilimumab + nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Variability of SpO2 Measurements Depending on the Choice of Finger for Sensor Placement
Status: ENROLLING_BY_INVITATION
Conditions: Hypoxia|Hypercapnia
Interventions: OTHER: Breathing a mixture of O2, N2 and CO2 and monitoring SpO2 on each finger
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Atezolizumab in Combination With a Multi-Kinase Inhibitor for the Treatment of Unresectable, Locally Advanced, or Metastatic Liver Cancer
Status: RECRUITING
Conditions: Locally Advanced Hepatocellular Carcinoma|Metastatic Hepatocellular Carcinoma|Stage III Hepatocellular Carcinoma AJCC v8|Stage IIIA Hepatocellular Carcinoma AJCC v8|Stage IIIB Hepatocellular Carcinoma AJCC v8|Stage IV Hepatocellular Carcinoma AJCC v8|Stage IVA Hepatocellular Carcinoma AJCC v8|Stage IVB Hepatocellular Carcinoma AJCC v8|Unresectable Hepatocellular Carcinoma
Interventions: BIOLOGICAL: Atezolizumab|DRUG: Cabozantinib|DRUG: Lenvatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Maolactin™ FMR on Exercise Recovery, Inflammation and Muscle Comfort in an Otherwise Healthy Population
Status: NOT_YET_RECRUITING
Conditions: Chronic Inflammation|Mobility|Muscle Pain|Joint Pain
Interventions: DRUG: Maolactin|DRUG: Maltodextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Short and Long Term Exposure to Unique, Time-Varying Pulsed Electro-Magnetic Fields in Refractory Carpal Tunnel Syndrome
Status: COMPLETED
Conditions: Refractory Carpal Tunnel Syndrome|Neurpathic Pain|Neuromodulaton
Interventions: DEVICE: reduction of pain scores by magnetic energy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Pharmacokinetics of Oral CellCept (Mycophenolate Mofetil) in Pediatric Liver Transplant Recipients on Concomitant Treatment With Cyclosporine and Corticosteroids
Status: TERMINATED
Conditions: Pediatric Liver Transplantation
Interventions: DRUG: Corticosteroids|DRUG: Cyclosporine|DRUG: mycophenolate mofetil
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Accuracy Of A Novel Platelet Activity Assay In Humans On Antiplatelet Agents: Pharmacodynamics And Comparison With Light Transmission Aggregometry
Status: RECRUITING
Conditions: Platelet Activation Testing Before/After Anti-platelet Therapy|Healthy
Interventions: DRUG: Aspirin|DRUG: Clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Irinotecan and Panitumumab as 3rd Line Treatment for mCRC Without KRAS Mutations
Status: COMPLETED
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: Irinotecan|DRUG: Panitumumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Novel Sound Changing Principles in Hearing Instruments to Determine Their Application - 2019_04
Status: COMPLETED
Conditions: Hearing Loss
Interventions: DEVICE: Hearing Aid without frequency lowering enabled|DEVICE: Hearing Aid with frequency lowering enabled
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Injections of Steroids and Autologous Platelet Rich Plasma in the Oral Erosions of Pemphigus Vulgaris
Status: COMPLETED
Conditions: Oral Pemphigus Vulgaris
Interventions: OTHER: Autologous Platelet rich plasma|DRUG: Triamcinolone Acetonide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Preventing Relapse in Schizophrenia: Oral Antipsychotics Compared To Injectables: Evaluating Efficacy
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder
Interventions: DRUG: Risperidone microspheres|DRUG: Risperidone|DRUG: Olanzapine|DRUG: Quetiapine|DRUG: Ziprasidone|DRUG: Aripiprazole|DRUG: Paliperidone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I/II Trial of a Malaria Vaccine in Adults Living in the United States of America
Status: COMPLETED
Conditions: Plasmodium Falciparum Malaria
Interventions: BIOLOGICAL: Falciparum Malaria Protein 11 with AS01B adjuvant.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Intermittent Abdominal Pressure Ventilation in Neuromuscular Patients
Status: RECRUITING
Conditions: Neuromuscular Diseases
Interventions: DEVICE: Intermittent Abdominal Pressure Ventilation|DEVICE: Usual ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Ramucirumab and Docetaxel in Participants With Solid Tumors
Status: COMPLETED
Conditions: Malignant Solid Tumor
Interventions: BIOLOGICAL: Ramucirumab|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Repetative Transcranial Magnetic Stimulation Therapy for Stroke Patients
Status: RECRUITING
Conditions: Lower Urinary Tract Symptoms
Interventions: DEVICE: Low Frequency rTMS Protocol|DEVICE: Sham rTMS Protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study With Jaktinib Hydrochloride Cream Applied Topically to Subjects With Alopecia Areata
Status: ACTIVE_NOT_RECRUITING
Conditions: Alopecia Areata(AA)
Interventions: DRUG: Jaktinib hydrochloride cream|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Hydroxychloroquine and Unexplained Recurrent Miscarriage
Status: COMPLETED
Conditions: Unexplained Recurrent Miscarriage
Interventions: DRUG: Hydroxychloroquine|DRUG: Folic Acid|DRUG: Low-dose aspirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of the Reversibility of Vigilance Dysfunction at 6 Months of Continuous Positive Airways Pressure (CPAP) in Patients With Obstructive Sleep Apnea/Hypopnea Syndrome (OSAHS)
Status: COMPLETED
Conditions: Vigilance Dysfunction
Interventions: DIAGNOSTIC_TEST: tests of attentional performance
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reconstruction Method and Delayed Gastric Emptying After Pancreatic Surgery
Status: COMPLETED
Conditions: Pancreatic Cancer|Surgery|Improvement of Perioperative Outcome
Interventions: PROCEDURE: antecolic reconstruction|PROCEDURE: retrocolic reconstruction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effectiveness of Seasonal Malaria Chemoprevention in Nampula Province, Mozambique: Type Two Hybrid Implementation Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Malaria
Interventions: DRUG: Chemopreventive Agent - SPAQ|DRUG: Control Test - no drugs given
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Dexmedetomidine for Prophylaxis Against PONV in Highly Susceptible Patients.
Status: COMPLETED
Conditions: Postoperative Nausea and Vomiting|Head and Neck Surgeries
Interventions: DRUG: Dexmedetomidine Hydrochloride 0.5 mic/kg bolus|DRUG: Dexmedetomidine Hydrochloride 0.75 mic/kg bolus|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Scheduled Telephone Intervention for Individuals With Spinal Cord Injury and Their Families
Status: COMPLETED
Conditions: Spinal Cord Injury
Interventions: BEHAVIORAL: Scheduled Telephone Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of the Aquaretic Tolvaptan on Nitric Oxide System
Status: COMPLETED
Conditions: Autosomal Dominant Polycystic Kidney Disease
Interventions: DRUG: Tolvaptan|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment Strategies for Unruptured Intracranial Aneurysms in the Chinese Population China Treatment Trial for Unruptured Intracranial Aneurysm (ChTUIA)
Status: RECRUITING
Conditions: Unruptured Intracranial Aneurysm
Interventions: OTHER: observation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Anifrolumab Asian PhIII Efficacy Study for Systemic Lupus Erythematosus (SLE)
Status: ACTIVE_NOT_RECRUITING
Conditions: Active Systemic Lupus Erythematosus
Interventions: BIOLOGICAL: Anifrolumab|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Testing if Fast or Slow rTMS is Better for the Treatment of Posttraumatic Stress Disorder (PTSD)
Status: COMPLETED
Conditions: Posttraumatic Stress Disorder|Depression
Interventions: DEVICE: Repetitive Transcranial Magnetic Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Back-loaded vs Preloaded Fiducial Needles in EUS-guided Fiducial Marker Placement in Pancreatic Cancer.
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DEVICE: Back-loaded Needle (Device)|DEVICE: Preloaded Needle (Device)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Brief Title: Project 4 Example: Mixed Hybrid Checklist
Status: RECRUITING
Conditions: Incidental Findings|Visual Attention|Visual Search|Hybrid Search
Interventions: BEHAVIORAL: Stimulus Type|BEHAVIORAL: Target Presence|BEHAVIORAL: Checklist
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: International Subarachnoid Aneurysm Trial II
Status: ACTIVE_NOT_RECRUITING
Conditions: Intracranial Hemorrhage Ruptured Aneurysm
Interventions: PROCEDURE: surgical management|PROCEDURE: Endovascular management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Administration of Esmolol on Nociception Level-guided Control of Nociception.
Status: RECRUITING
Conditions: Opioid Use, Unspecified|Anesthesia|Nociceptive Pain
Interventions: DRUG: Esmolol Hydrochloride|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Reducing Fatigue in People With Multiple Sclerosis by Treatment With TENS
Status: RECRUITING
Conditions: Multiple Sclerosis
Interventions: DEVICE: Transcutaneous electrical nerve stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Effectiveness Study of MIST Therapy Versus Negative Pressure Wound Therapy
Status: WITHDRAWN
Conditions: Wounds
Interventions: DEVICE: MIST Therapy|DEVICE: Vacuum Assisted Closure|DEVICE: MIST Therapy and Negative Pressure Wound Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of P38 Inhibitor (4) Monotherapy in Patients With Active Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: P38 Inhibitor (4)|DRUG: P38 Inhibitor (4)|DRUG: P38 Inhibitor (4)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Unstable Fractures of the Distal Radius: Trial of Volar Plate Versus Dorsal Nail Plate Fixation
Status: COMPLETED
Conditions: Distal Radius Fractures
Interventions: PROCEDURE: Volar plate|PROCEDURE: Dorsal nail plate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of Modifications to Radical Prostatectomy
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Cancer
Interventions: PROCEDURE: Lymph node template|PROCEDURE: Transverse versus vertical closure|DRUG: antibiotic prophylaxis|DRUG: Hemostatic Agent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CR845-CLIN3105: A Study to Evaluate the Safety and Effectiveness of CR845 in Hemodialysis Patients With Moderate-to-Severe Pruritus
Status: COMPLETED
Conditions: Uremic Pruritus
Interventions: DRUG: CR845 0.5 mcg/kg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 2010/2011 Trivalent Influenza Vaccination
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: TIV 2010/2011 influenza vaccine|BIOLOGICAL: TIV 2010/2011 influenza vaccine|BIOLOGICAL: TIV 2010/2011 influenza vaccine|BIOLOGICAL: INT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intranasal Injection of Dexmedetomidine and Bupivacaine in Septoplasty Surgeries
Status: UNKNOWN
Conditions: Intranasal Dexmedetomidine|Intranasal Bupivacaine|Septoplasty Surgeries
Interventions: DRUG: Dexmedetomidine|DRUG: Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Velphoro on Serum Phosphate and Albumin in Peritoneal Dialysis Patients
Status: COMPLETED
Conditions: Peritoneal Dialysis Complication|Hyperphosphatemia|Hypoalbuminemia
Interventions: DRUG: Sucroferric Oxyhydroxide Chewable Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Subscleral Trabeculectomy With Iris Incarceration in Buphthalmous
Status: COMPLETED
Conditions: Iris Incarceration
Interventions: DEVICE: Subscleral Trabeculectomy (SST) with Iris incarceration|DEVICE: Conventional trabeculotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Study Comparing MB02 And US And EU Avastin® In Healthy Male Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: MB02 (Bevacizumab Biosimilar)|DRUG: EU approved Avastin®|DRUG: US licenced Avastin®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Ranibizumab for the Inhibition of Neovascularization in Pterygia
Status: COMPLETED
Conditions: Pterygium
Interventions: DRUG: ranibizumab|DRUG: ranibizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multiple Ascending Dose Study of Safety and Pharmacokinetics of NP10679 in Normal Healthy Volunteers
Status: COMPLETED
Conditions: Stroke, Ischemic|Pain, Postoperative|Substance Abuse|Subarachnoid Hemorrhage
Interventions: DRUG: Placebo|DRUG: NP10679
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study of SHR8554 Injection for the Treatment of Pain After Abdominal Surgery.
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: SHR8554 Injection|DRUG: SHR8554 Injection|DRUG: Placebo|DRUG: Morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prescribe Exercise for Prevention of Falls and Fractures: A Family Health Team Approach
Status: COMPLETED
Conditions: Fall and Fractures Prevention
Interventions: OTHER: Identification of patients at risk, tailored exercise prescription, motivational interviewing, review of behavioural outcomes
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Drug and Risk Counseling Among Methadone Patients in Jakarta, Indonesia
Status: COMPLETED
Conditions: HIV Risk Behaviors|Heroin Injection|Retention in Methadone Treatment
Interventions: BEHAVIORAL: Behavioral Drug and Risk Counseling (BDRC)|BEHAVIORAL: methadone maintenance treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Supplementation of Glutamine and Fish Oil Versus Placebo in Patients With Heart Failure
Status: COMPLETED
Conditions: Heart Failure
Interventions: DRUG: Glutamine and Fish Oil Supplementation|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Role of Oral Lactoferrin in Prevention of Recurnt Bacterial Vaginosis in Pregnancy
Status: RECRUITING
Conditions: Bacterial Vaginosis &#X7C; Vaginal &#X7C; Microbiology
Interventions: DRUG: lactoferrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High-dose Erythropoietin for Asphyxia and Encephalopathy
Status: COMPLETED
Conditions: Neonatal Encephalopathy|Birth Asphyxia
Interventions: DRUG: Normal saline placebo|DRUG: Erythropoietin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Oral Enteral Nutrition in Delayed Onset Radiotherapy-related Swallowing Disorder in Nasopharyngeal Carcinoma
Status: COMPLETED
Conditions: Dysphagia
Interventions: DEVICE: Intermittent Oral-esophageal Tube Feeding|DEVICE: nasogastric tube feeding
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Amodiaquine-artesunate in Children Aged 6-59 Months With Uncomplicated P. Falciparum Malaria
Status: COMPLETED
Conditions: Malaria
Interventions: DRUG: AQAS
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Whole Blood and Plasma Sample Collection for the Development of Antipsychotic Immunoassays From Participants Taking Aripiprazole, Olanzapine, Paliperidone, or Risperidone
Status: COMPLETED
Conditions: Immunoassay|Antipsychotic
Interventions: DRUG: Aripiprazole|OTHER: Olanzapine|DRUG: Paliperidone|DRUG: Risperidone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A New Birth Weight Prediction in Chinese Population
Status: UNKNOWN
Conditions: Birth Weight
Interventions: DIAGNOSTIC_TEST: 2D and 3D ultrasonography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Acetate and Age-associated Arterial Dysfunction
Status: RECRUITING
Conditions: Aging|Vascular Stiffness|Vascular Dilation
Interventions: DRUG: Calcium Acetate Oral Solution|DRUG: Calcium Carbonate Oral Suspension
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Treating Obstructive Sleep Apnea in Epilepsy
Status: COMPLETED
Conditions: Epilepsy|Sleep Apnea|Obstructive Sleep Apnea
Interventions: DEVICE: continuous positive airway pressure (CPAP)|DEVICE: Placebo-CPAP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Brain Regulation of Appetite in Twins
Status: COMPLETED
Conditions: Obesity|Appetite
Interventions: DEVICE: Functional Magnetic Resonance Imaging|RADIATION: Dual Energy X-ray absorptiometry|OTHER: Questionnaires|OTHER: Mood and Appetite Ratings|OTHER: Test Meals|OTHER: Computer Tests|PROCEDURE: Intravenous Catheter (IV) placement
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Magnesium Oral Supplementation for Acute Non-specific Low Back Pain
Status: COMPLETED
Conditions: Low Back Pain|Acute Pain
Interventions: DRUG: Magnesium|DRUG: NSAID|DRUG: paracetamol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Liraglutide in Healthy Japanese Volunteers
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: liraglutide|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: 5-Year Global Study on MAST™ Minimally Invasive Fusion Procedures to Treat Degenerative Lumbar Spine (MASTERS-D2)
Status: ACTIVE_NOT_RECRUITING
Conditions: Intervertebral Disc Degeneration
Interventions: DEVICE: Minimally invasive lumbar fusion
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy of Collagen Sponge on Palatal Wound Healing
Status: RECRUITING
Conditions: Gingival Recession|Inadequately Attached Gingiva
Interventions: PROCEDURE: Palatal soft tissue graft harvesting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Placebo-Controlled Study of Mometasone Furoate Nasal Spray (MFNS) 200 mcg Once Daily (QD) in the Treatment of Seasonal Allergic Rhinitis (Study P05067)(COMPLETED)
Status: COMPLETED
Conditions: Seasonal Allergic Rhinitis
Interventions: DRUG: mometasone furoate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness Study of Circumferential vs. Segmental Ablation in Paroxysmal Atrial Fibrillation
Status: COMPLETED
Conditions: Paroxysmal Atrial Fibrillation|Atrial Arrhythmia
Interventions: PROCEDURE: Circumferential Pulmonary Vein Ablation|PROCEDURE: Segmental Pulmonary Vein Isolation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Diet Control and Resistance Exercise Training on Obesity Adults With Knee Osteoarthritis
Status: UNKNOWN
Conditions: Osteoarthritis, Knee|Obesity|Diet, Healthy|Training Group, Sensitivity
Interventions: BEHAVIORAL: Elastic knee joint movement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Therapeutic Effect of EGF Cream for Cutaneous Adverse Event of EGFR Inhibitors
Status: UNKNOWN
Conditions: Drug-Related Side Effects and Adverse Reactions|Epidermal Growth Factor
Interventions: DRUG: Repair Control EGF®|DRUG: Cream without rhEGF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Levocetirizine DiHCl Tablets 5mg of Dr. Reddy's Under Fed Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Levocetirizine DiHCl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study on the Safety of Double and a Half Layered Esophagojejunal Anastomosis in Curative Gastrectomy
Status: UNKNOWN
Conditions: Surgery--Complications
Interventions: PROCEDURE: double and a half layered esophagojejunal anastomosis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Influence of IgY Max on Inflammatory Markers and the Gut Microbiome
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Immunoglobulin Y|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Predictive Value of 99mTc- Albumin Spheres Before 90Y- SIR Therapy
Status: COMPLETED
Conditions: Colorectal Cancer|Liver Metastases
Interventions: DRUG: MAA for diagnostic SPECT imaging|DRUG: Diagnostic B20- SPECT imaging.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: GEMOX Combined With Donafenib and Tislelizumab in Biliary Tract Cancer
Status: UNKNOWN
Conditions: Biliary Tract Carcinoma
Interventions: COMBINATION_PRODUCT: Combination of Gemcitabine, Oxaliplatin, Donafenib and Tislelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Peginterferon Alfa-2a (40KD) (PEGASYS®) in Participants With Hepatitis B Envelope Antigen (HBeAg) - Positive Chronic Hepatitis B
Status: COMPLETED
Conditions: Hepatitis B, Chronic
Interventions: DRUG: Peginterferon alfa-2a
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Extracorporeal Membrane Oxygenation (ECMO) in Non-intubated Patients With Acute Respiratory Distress Syndrome (ARDS)
Status: COMPLETED
Conditions: ARDS
Interventions: DEVICE: ECMO|PROCEDURE: ECMO in non-intubated patients
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Muscle Energy Techniques and Self-Stretching in Nonspecific Neck Pain
Status: COMPLETED
Conditions: Nonspecific Neck Pain|Exercise
Interventions: OTHER: Self-Streching Exercises|OTHER: Post-Isometric Relaxation Exercises|OTHER: Reciprocal-Inhibiton Exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effects of Intravitreal Ranibizumab for Macular Edema With Nonproliferative Diabetic Retinopathy
Status: COMPLETED
Conditions: Nonproliferative Diabetic Retinopathy
Interventions: DRUG: Lucentis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: HER-TEMPO - Real World Treatment-related Outcomes on T-DXd in Canada
Status: RECRUITING
Conditions: Unresectable Breast Cancer|Metastatic Breast Cancer|HER2-low Expressing Breast Cancer|HER2-positive Breast Cancer
Interventions: DRUG: Trastuzumab deruxtecan
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of KTE-X19 in Adult Japanese Participants With Relapsed/Refractory Mantle Cell Lymphoma or Relapsed/Refractory B-precursor Acute Lymphoblastic Leukemia
Status: RECRUITING
Conditions: Relapsed/Refractory Mantle Cell Lymphoma|Relapsed/Refractory B-precursor Acute Lymphoblastic Leukemia
Interventions: DRUG: KTE-X19|DRUG: Cyclophosphamide|DRUG: Fludarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ALDH Enzyme in CRF With Advanced GI Cancer
Status: UNKNOWN
Conditions: Fatigue|Gastrointestinal Cancer|Aldehyde Dehydrogenase
Interventions: DRUG: ALDH enzyme supplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Clinical Study of T3011 in Combination With Regorafenib in Patients With Advanced Colorectal Cancer
Status: RECRUITING
Conditions: Advanced Colorectal Cancer
Interventions: DRUG: T3011|DRUG: Regorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nintedanib Compared With Placebo in Treating Against Radiation-Induced Pneumonitis in Patients With Non-small Cell Lung Cancer That Cannot Be Removed by Surgery and Are Undergoing Chemoradiation Therapy
Status: TERMINATED
Conditions: Lung Non-Squamous Non-Small Cell Carcinoma|Radiation-Induced Pneumonitis|Stage II Lung Non-Small Cell Cancer AJCC v7|Stage IIA Lung Non-Small Cell Carcinoma AJCC v7|Stage IIB Lung Non-Small Cell Carcinoma AJCC v7|Stage III Lung Non-Small Cell Cancer AJCC v7|Stage IIIA Lung Non-Small Cell Cancer AJCC v7|Stage IIIB Lung Non-Small Cell Cancer AJCC v7|Stage IV Lung Non-Small Cell Cancer AJCC v7
Interventions: BIOLOGICAL: Durvalumab|DRUG: Nintedanib|OTHER: Placebo|PROCEDURE: Quality-of-Life Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phase 2 Trial of Mesenchymal Stem Cells in Systemic Lupus Erythematosus (MiSLE)
Status: RECRUITING
Conditions: Systemic Lupus Erythematosus
Interventions: DRUG: Low Dose Mesenchymal Stem Cells (MSCs)|DRUG: High Dose Mesenchymal Stem Cells (MSCs)|DRUG: Placebo Infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Standardized Patient-Centered Medication Review in Home Hospice
Status: ACTIVE_NOT_RECRUITING
Conditions: Hospices|Poly Pharmacy|Deprescriptions|Caregivers|Palliative Care|Prescription Drug Overuse|Interdisciplinary Communication
Interventions: BEHAVIORAL: NIA Medication Management - Active Comparator|BEHAVIORAL: STOPPFrail (Screening Tool of Older Persons Prescriptions)|BEHAVIORAL: "Discontinuing Medication Appropriately" and "Understanding the Art of Communication about Deprescribing"|BEHAVIORAL: "Key Approaches to Support Informal Family Caregivers in Managing Medications"
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Driving Simulator Study Comparing Two Modes of Presbyopic Correction With Contact Lenses
Status: COMPLETED
Conditions: Presbyopia
Interventions: DEVICE: Lotrafilcon B MF|DEVICE: Lotrafilcon B MV|DEVICE: Lotrafilcon B SVD|DEVICE: Comfilcon A MF|DEVICE: Habitual contact lenses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose:
Clinical trial: A Multi-Center, Randomized, Open-Label Study to Assess the Immunogenicity and Safety of Denosumab in Pre-filled Syringe Compared to Vial in Subjects With Low Bone Mineral Density
Status: COMPLETED
Conditions: Low Bone Mineral Density|Osteopenia|Osteoporosis
Interventions: BIOLOGICAL: denosumab|BIOLOGICAL: denosumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acoustic and Volumetric Measurements in Order to Objectify Bronchial Congestion in Patients With Obstructive Respiratory Pathologies Within the Framework of Their Management in Respiratory Physiotherapy for Decongestion
Status: UNKNOWN
Conditions: COPD
Interventions: OTHER: Measurement records
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of Korean Red Ginseng Supplementation on Glucose Control
Status: COMPLETED
Conditions: Diabetes
Interventions: DIETARY_SUPPLEMENT: KRG|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: rTMS for PTSD Comorbid With Major Depressive Disorder
Status: COMPLETED
Conditions: Posttraumatic Stress Disorder|Major Depressive Disorder|Transcranial Magnetic Stimulation, Repetitive
Interventions: DEVICE: Transcranial Magnetic Stimulation (TMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial of Metformin in the Maintenance of Non-Hodgkin's Lymphoma Patients
Status: UNKNOWN
Conditions: Lymphoma, Large B-Cell, Diffuse|Stage III Follicular Lymphoma
Interventions: DRUG: Metformin|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Study of Early Stage Osteonecrosis of Femoral Head With Human Umbilical Cord Mesenchymal Stem Cells (19#iSCLife®-ONFH)
Status: SUSPENDED
Conditions: Osteonecrosis of Femoral Head
Interventions: DRUG: Allogeneic umbilical cord mesenchymal stem cells (SCLnow 19#)|PROCEDURE: core decompression
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: 6-minute Stepper Test and Pulmonary Rehabilitation in Patients With Chronicle Obstructive Pulmonary Disease
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease|Pulmonary Rehabilitation|6-minute Stepper Test
Interventions: OTHER: 2 times : 6-minute stepper test with a rest of 20min between each test.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Seasonal Influenza Vaccine High Dose Boosting in Solid Organ Transplant Recipients
Status: RECRUITING
Conditions: Solid Organ Transplant
Interventions: DRUG: Fluzone High-Dose - 2 doses|DRUG: Fluzone High-Dose - 1 dose of HD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Bacteriological Setting Before Prosthesis Implantation With One Stage Surgery in Prosthetic Joint Infection
Status: COMPLETED
Conditions: Prosthetic Joint Infection
Interventions: PROCEDURE: intraoperative samples
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The "Peripheral Access Utilizing Sonographic Evaluation" Study
Status: WITHDRAWN
Conditions: DIVA
Interventions: PROCEDURE: Traditional Landmark Technique (TLT)|DEVICE: ultrasound guided peripheral intravenous access (USGPIVA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Ranibizumab for Recalcitrant Wet Age-related Macular Degeneration in Eyes Previously Switched From Bevacizumab and/or Ranibizumab to Aflibercept.
Status: COMPLETED
Conditions: Recalcitrant Wet Age-related Macular Degeneration
Interventions: DRUG: Ranibizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I Trial to Assess the Safety of Tenofovir Gel and Film Formulations: FAME 04
Status: COMPLETED
Conditions: HIV
Interventions: DRUG: 1% vaginally applied tenofovir gel|DRUG: Tenofovir film- 10mg|DRUG: Tenofovir Film-40 mg|OTHER: HEC Placebo Gel|OTHER: Placebo Vaginal Film
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Safety and Immunogenicity of the Butantan Institute Influenza Vaccine Compared to Sanofi Pasteur Influenza Vaccine
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Butantan Institute Trivalent Seasonal Influenza Vaccine|BIOLOGICAL: Sanofi Trivalent Seasonal Influenza Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of General Anesthesia Method on Cardiac Risk Patients on Ischemia Modified Markers
Status: NOT_YET_RECRUITING
Conditions: Anesthesia
Interventions: PROCEDURE: TIVA|PROCEDURE: GENERAL ANESTHESIA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Samu Save Sepsis: Early Goal Directed Therapy in Pre Hospital Care of Patients With Severe Sepsis and/or Septic Shock
Status: COMPLETED
Conditions: Severe Septic Syndrome (Severe Sepsis and Septic Shock) Diagnosed and Treated by Mobile Intensive Care Unit
Interventions: DRUG: Ceftriaxone|DRUG: Piperacillin tazobactam|DRUG: Norepinephrine|DRUG: Hydrocortisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Isolated Roux-en-Y Reconstruction After Pancreaticoduodenectomy
Status: UNKNOWN
Conditions: Pancreatic Neoplasms|Bile Duct Neoplasms|Ampullary Neoplasms|Duodenal Neoplasms|Pancreatitis
Interventions: PROCEDURE: Billroth-II-type reconstruction|PROCEDURE: Isolated Roux-en-Y type reconstruction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neo-Adjuvant Gemcitabine and Cisplatin in Treating Patients With Early Stage of Non Small Cell Lung Cancer
Status: COMPLETED
Conditions: Carcinoma, Non-Small-Cell-Lung Cancer
Interventions: DRUG: Gemcitabine|DRUG: cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Ketoconazole 2% Foam in the Treatment of Pityrosporum Folliculitis
Status: COMPLETED
Conditions: Pityrosporum Folliculitis
Interventions: DRUG: ketoconazole 2% foam
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Functional Kinesio Taping on Subacromial Space in Athletes With Rotator Cuff Tendinopathy
Status: COMPLETED
Conditions: Sports Physical Therapy
Interventions: OTHER: Kinesio Taping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Probing the Dorsolateral Prefrontal Cortex and Central Executive Network for Improving Neuromodulation in Depression
Status: RECRUITING
Conditions: Major Depressive Disorder
Interventions: DEVICE: Individualized CEN-targeted rTMS|DEVICE: Neuronavigated rTMS|DEVICE: Scalp-targeted rTMS|DEVICE: Sham rTMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Topical Antibiotic Irrigation (Gentamicin) in Prophylaxis of Midfacial Fracture Surgical Wounds
Status: TERMINATED
Conditions: Surgical Site Infection
Interventions: DRUG: topical irrigation with gentamicin (80mg diluted in 1L 0.9% normal saline)|DRUG: topical irrigation with sterile normal saline (NS)|DRUG: intravenous (IV) prophylactic antibiotic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION