pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Clinical Trial of Brentuximab Vedotin in Classical Hodgkin Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Hodgkin Lymphoma
Interventions: DRUG: brentuximab vedotin|DRUG: doxorubicin|DRUG: vinblastine|DRUG: dacarbazine|DRUG: G-CSF|DRUG: nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of a Health Belief Model-Based Community Educational Program to Increase the Awareness of Atrial Fibrillation Among Older Adults: a Randomized Controlled Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Atrial Fibrillation (AF)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Dose Response Effect of Probiotics for the Prevention of Antibiotic-associated Diarrhea in Chinese Adults
Status: COMPLETED
Conditions: Antibiotic-associated Diarrhea
Interventions: DIETARY_SUPPLEMENT: Probiotic|DIETARY_SUPPLEMENT: Probiotic|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of AZD2936 Anti-TIGIT/Anti-PD-1 Bispecific Antibody in Participants With Advanced or Metastatic NSCLC
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-Small-Cell Lung Carcinoma
Interventions: DRUG: AZD2936
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability of Intravenous LLP2A-Alendronate for Osteopenia Secondary to Glucocorticoids
Status: COMPLETED
Conditions: Osteopenia|Osteoporosis|Osteonecrosis
Interventions: DRUG: LLP2A-ALENDRONATE|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Fish Oil (Omega 3), Immune Function, and Mood
Status: COMPLETED
Conditions: Inflammation
Interventions: DIETARY_SUPPLEMENT: Omega 3 (Fish Oil) Supplementation|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Implementing Scalable, PAtient-centered Team-based Care for Adults With Type 2 Diabetes and Health Disparities (iPATH)
Status: NOT_YET_RECRUITING
Conditions: Diabetes Mellitus, Type 2
Interventions: OTHER: iPATH implementation approach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Time-trend Analysis of Clinical Characteristic and Outcomes in Patients With Unprotected Left Main Coronary Artery Disease Treated With PCI Over a 10-year Period
Status: ACTIVE_NOT_RECRUITING
Conditions: Cardiovascular Diseases
Interventions: DEVICE: The AngioliteTM Durable Fluoroacrylate Polymer-based Sirolimus-Eluting Stent
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Phase II Study of Curcumin vs Placebo for Chemotherapy-Treated Breast Cancer Patients Undergoing Radiotherapy
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Placebo|DRUG: Curcumin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pulmonary Vein Isolation Versus Botulinum Toxin Injection Plus Pulmonary Vein Isolation in Patients With Atrial Fibrillation
Status: UNKNOWN
Conditions: Paroxysmal Atrial Fibrillation|Persistent Atrial Fibrillation
Interventions: PROCEDURE: Pulmonary vein isolation|DRUG: Botulinum Toxin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: To Evaluate OBI-833/OBI-821 in Patients With Locally Advanced, Globo H-Positive Esophageal Cancer for Recurrence
Status: RECRUITING
Conditions: Esophageal Cancer
Interventions: BIOLOGICAL: OBI-833/OBI-821
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Clinical Efficacy and Safety of Finerenone in the Treatment of Primary Aldosteronism
Status: RECRUITING
Conditions: Primary Aldosteronism|Finerenone|Mineralocorticoid Receptor Antagonist
Interventions: DRUG: Finerenone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of CM310 in Patients With Moderate-to-Severe Atopic Dermatitis
Status: RECRUITING
Conditions: Atopic Dermatitis
Interventions: DRUG: CM310|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Collection of Blood, Bone Marrow, Leukapheresis, and Tissue Biopsy Samples From Patients and Their Family Members for Center for Human Immunology, Autoimmunity, and Inflammatory Diseases Laboratory Research Studies
Status: TERMINATED
Conditions: Idopathic Inflammatory/Autoimmune Syndromes
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase 1 Study of INCMGA00012 in Patients With Advanced Solid Tumors
Status: COMPLETED
Conditions: Locally Advanced Solid Tumors|Metastatic Solid Tumors
Interventions: DRUG: retifanlimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Aqueous Extract of Garlic and Nystatin Mouthwash in Denture Stomatitis
Status: COMPLETED
Conditions: Denture Stomatitis
Interventions: DRUG: garlic , nystatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Symbicort on Sleep Quality in Patients With Emphysema
Status: UNKNOWN
Conditions: Emphysema|Poor Sleep Quality
Interventions: DRUG: Budesonide/formoterol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility and Efficacy of a Home-based, Computerized Cognitive Training Program in Pediatric Sickle Cell Disease
Status: COMPLETED
Conditions: Anemia, Sickle Cell
Interventions: BEHAVIORAL: Cogmed RM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Efficacy & Safety of Resusix With FP24 in Patients With Acquired Coagulopathy
Status: TERMINATED
Conditions: Coagulopathy
Interventions: BIOLOGICAL: Resusix|BIOLOGICAL: FP24 (Frozen Plasma)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Quantitative Assessment of Diffusion Spectrum Imaging in Breast Cancer
Status: UNKNOWN
Conditions: Breast Carcinoma; Magnetic Resonance Imaging; Diffusion Spectrum Imaging
Interventions: DIAGNOSTIC_TEST: Diffusion Spectrum Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Berkeley Orthokeratology Study
Status: COMPLETED
Conditions: Astigmatism|Myopia
Interventions: DEVICE: Polymethyl Methacrylate-Silicone Contact Lenses|DEVICE: Polymethyl Methacrylate Contact Lenses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Investigational Dementia Treatment Study
Status: RECRUITING
Conditions: Dementia, Mild
Interventions: DEVICE: transcranial alternative current stimulation (tACS)|OTHER: cognitive exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The MATCH Study: Mindfulness And Tai Chi for Cancer Health
Status: ACTIVE_NOT_RECRUITING
Conditions: Cancer
Interventions: BEHAVIORAL: Mindfulness Based Cancer Recovery (MBCR)|BEHAVIORAL: Tai Chi/Qigong (TCQ) for Cancer Patients
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of Irritation That Potentially Could be Caused by Two Facial Gels Applied to Opposite Sides of the Face
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: Tretinoin Facial Gel|DRUG: Adapalene/Benzoyl Peroxide Facial Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: One-month Clinical Evaluation of Silicone Hydrogel Definitive 65 HPT Contact Lenses
Status: COMPLETED
Conditions: Ametropia
Interventions: DEVICE: Definitive 65 HPT contact lenses|DEVICE: Definitive 65 contact lenses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial of STAtin Therapy for Reducing Events in the Elderly (STAREE)
Status: ACTIVE_NOT_RECRUITING
Conditions: Independent Living|Disability Free Survival|Elderly|Healthy
Interventions: DRUG: Atorvastatin|DRUG: Placebo (for Atorvastatin)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Serotonin Level on Constipation Caused by Chemotherapy in Patients With Ovarian, Fallopian Tube, or Primary Peritoneal Cancer
Status: TERMINATED
Conditions: Constipation|Bowel Obstruction|Fallopian Tube Cancer|Ovarian Cancer|Peritoneal Cavity Cancer
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Bronchiectasis Prevalence in Patients With Primary Humoral Immunodefiency in Champagne-Ardenne Region, France
Status: RECRUITING
Conditions: Primary Immunodeficiency|Common Variable Immunodeficiency|Igg Subclass Deficiency|Selective IgM Deficiency
Interventions: OTHER: Blood test|OTHER: chest CT scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: A Randomized Trial of a Biolimus-Coated Balloon Versus POBA in Small Vessel Coronary Artery Disease
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DEVICE: Biolimus|DEVICE: Powerline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, and Pharmacodynamics of NOV-001 in Adult Subjects
Status: TERMINATED
Conditions: Healthy Volunteers|Enteric Hyperoxaluria
Interventions: COMBINATION_PRODUCT: NOV-001|BIOLOGICAL: NB1000S|DRUG: NB2000P|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Natriuretic Peptides and Metabolic Risk in Obesity
Status: WITHDRAWN
Conditions: Obesity|Hyperinsulinemia
Interventions: DRUG: Nesiritide|DRUG: Insulin|OTHER: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study of Mirikizumab (LY3074828) in Healthy Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Mirikizumab - IV|DRUG: Mirikizumab - SC|DRUG: Placebo - IV|DRUG: Placebo - SC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Observational Study on the Preparation of the Implant Site With Piezosurgery vs Drill: Comparison Between the Two Methods in Terms of Post-operative Pain, Surgical Times and Operational Advantages
Status: COMPLETED
Conditions: Preparation of the Implant Site With Piezosurgery vs Drill
Interventions: DEVICE: preparation of the implant site with Piezosurgery vs drill
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Oxaliplatin Combined With Irinotecan Liposome Injection II Through Hepatic Artery Infusion (HAIC) Followed by 5-FU/LV (HAIC) or Tegorgor Oral Combination Therapy for Hepatic Metastasis of Pancreatic Cancer
Status: RECRUITING
Conditions: Pancreatic Neoplasms|Neoplasm Metastasis|Hepatic Metastasis of Pancreatic Cancer
Interventions: DRUG: Liposome Irinotecan Injection II combined with Oxaliplatin, Fluorouracil, Leucovorin|DRUG: Tegodor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Implementation of Telerehabilitation In Support of HOme-based Physical Exercise for Heart Failure
Status: COMPLETED
Conditions: Heart Failure, Systolic|Heart Failure, Diastolic|Chronic Kidney Diseases|Cardiorenal Syndrome
Interventions: BEHAVIORAL: Telerehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of CUSP06 in Patients With Platinum-Refractory/Resistant Ovarian Cancer and Other Advanced Solid Tumors
Status: RECRUITING
Conditions: Ovarian Cancer|Solid Tumor
Interventions: DRUG: CUSP06
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fluciclovine (Axumin) PET/CT vs. NaF PET/CT in Prostate Cancer Osseous Metastatic Disease
Status: WITHDRAWN
Conditions: Malignant Neoplasm of Prostate
Interventions: DEVICE: [F-18] NaF PET/CT|DEVICE: [F-18] fluciclovine PET/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Evaluate the Tolerance of an Acne Treatment in Sensitive Skin Subjects With Mild to Moderate Acne Vulgaris
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DEVICE: Acne Mask
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tui na for Peripheral Neuropathy Among People With HIV
Status: NOT_YET_RECRUITING
Conditions: Hiv
Interventions: BEHAVIORAL: Therapeutic Chinese foot massage|BEHAVIORAL: Placebo massage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Inhaled Fluticasone Furoate/Vilanterol Safety and Tolerability, PK and PD Study
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Fluticasone Furoate|DRUG: Fluticasone Furoate/Vilanterol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Feasibility and Efficacy of a Real-time Smoking Intervention Using Wearable Technology
Status: COMPLETED
Conditions: Tobacco Use Cessation
Interventions: BEHAVIORAL: Real-Time Smoking Intervention|BEHAVIORAL: Standard Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tranexamic Acid Per Inhalation for Treatment of Pulmonary Hemorrhage in Pediatric Patients
Status: COMPLETED
Conditions: Pulmonary Hemorrhage|MAPCA - Major Aortopulmonary Collateral Artery
Interventions: DRUG: Tranexamic Acid
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Morphological and Radiological Data in Patients With Urolithiasis
Status: UNKNOWN
Conditions: Urolithiasis
Interventions: PROCEDURE: Percutaneous Nephrolithotomy|PROCEDURE: Partial nephrectomy|PROCEDURE: Radical nephrectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Treatment of IgE Associated Eczema With Omega-3 Long Chain Polyunsaturated Fatty Acids in Infancy and the Development of Bronchial Asthma in Childhood
Status: UNKNOWN
Conditions: Food Allergy|Eczema|Sensitisation
Interventions: DIETARY_SUPPLEMENT: Omega-3 LCPUFA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Microbiological Study on Maxillary Complete Dentures of Two Different Materials
Status: UNKNOWN
Conditions: Denture Stomatitis
Interventions: OTHER: titanium dioxide denture|OTHER: rapid heat denture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study to Assess the Safety, Tolerability, and Pharmacokinetics of AMP-110 in Subjects With Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: BIOLOGICAL: AMP-110|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of MTPS9579A in Participants With Refractory Chronic Spontaneous Urticaria
Status: WITHDRAWN
Conditions: Chronic Spontaneous Urticaria
Interventions: DRUG: MTPS9579A|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Compare the Renal Protective Effects of Febuxostat and Benzbromarone
Status: COMPLETED
Conditions: Chronic Kidney Disease|Hyperuricemia|Abnormal Renal Function
Interventions: DRUG: Febuxostat|DRUG: Benzbromarone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Safety and Pharmacokinetics of WP1122 in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: WP1122|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: JAB-3068 Activity in Adult Patients With Advanced Solid Tumors
Status: UNKNOWN
Conditions: Advanced Solid Tumor|Esophageal Squamous Cell Carcinoma|Non Small Cell Lung Cancer|Head and Neck Squamous Cell Carcinoma
Interventions: DRUG: JAB-3068|DRUG: PD1 inhibitor
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Influence of Porcelain Fused to Metal ( PFM) and Zirconia Crowns on Periodontal Health
Status: UNKNOWN
Conditions: Periodontitis
Interventions: DEVICE: Zirconia crown|DEVICE: Porcelain metal crown
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Metformin in Coronary Artery Bypass Graft (CABG) (MetCAB) Trial
Status: COMPLETED
Conditions: Cardiovascular Disease|Ischemic Heart Disease
Interventions: DRUG: Metformin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Trial of Ribavirin in Patients With ACLF Due to Hepatitis E Virus
Status: UNKNOWN
Conditions: Acute on Chronic Hepatic Failure|Liver Failure|Hepatitis E Infection
Interventions: DRUG: Ribavirin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transversus Abdominis Plane Block in the Management of Acute Postoperative Pain Syndrome After Caesarean Section
Status: TERMINATED
Conditions: Pain
Interventions: DRUG: Levobupivacaine|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Health and Recovery Program in Increasing Physical Activity Level in Stage IA-IIIA Endometrial Cancer Survivors
Status: COMPLETED
Conditions: Cancer Survivor|Endometrial Carcinoma|Stage I Uterine Corpus Cancer AJCC v7|Stage IA Uterine Corpus Cancer AJCC v7|Stage IB Uterine Corpus Cancer AJCC v7|Stage II Uterine Corpus Cancer AJCC v7|Stage IIIA Uterine Corpus Cancer AJCC v7
Interventions: OTHER: Communication Intervention|OTHER: Counseling|OTHER: Fitbit tracker|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration|BEHAVIORAL: Telephone-Based Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety Study of Antria Cell Preparation Process to Enhance Facial Fat Grafting With Adipose Derived Stem Cells
Status: COMPLETED
Conditions: Lipoatrophy|Aging|Wrinkles
Interventions: BIOLOGICAL: SVF
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Minimally-Invasive Sponge on a String Device for Screening for Barrett's Esophagus
Status: COMPLETED
Conditions: Barrett Esophagus
Interventions: PROCEDURE: Biopsy|PROCEDURE: Biospecimen Collection|PROCEDURE: Endoscopic Procedure|DEVICE: Swallowable Sponge Cell Sampling Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Validation of a Novel Simplified Head up Tilt Test (HUTT) Protocol Versus the Conventional Protocol
Status: UNKNOWN
Conditions: Syncope|Syncope;Heat Induced
Interventions: DIAGNOSTIC_TEST: Fast HUTT|DIAGNOSTIC_TEST: Conventional HUTT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: PREVenting-ENvIronment-Reprotoxic Exposures Before In Vitro Fertilization (PREVENIR-FIV)
Status: NOT_YET_RECRUITING
Conditions: Infertility
Interventions: BEHAVIORAL: Visioconsulation|BEHAVIORAL: self-assessment questionnaire|BIOLOGICAL: hair sampling|BEHAVIORAL: self-assessment questionnaire on dedicated application|BEHAVIORAL: Specialized follow-up|BEHAVIORAL: self-assessment questionnaire for follow-up
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Effect of Laughter Yoga on Perceived Stress, Work Motivation, and Mental Well-Being
Status: COMPLETED
Conditions: Mental Health|Complementary Therapies
Interventions: BEHAVIORAL: Laughter Yoga Application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Drug-Drug Interaction Study Between DWC20155 / DWC20156 and DWC20163 in Healthy Volunteers
Status: UNKNOWN
Conditions: Healthy
Interventions: DRUG: Co-administration of DWC20155/DWC20156|DRUG: DWC20163
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Kaletra Monotheraphy Compared to Kaletra Based Triple Therapy to Treat HIV in Antiretroviral Naїve Patients
Status: COMPLETED
Conditions: HIV Infection
Interventions: DRUG: lopinavir/ritonavir|DRUG: lamivudine/zidovudine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Performance Nutrition for Residents and Fellows
Status: COMPLETED
Conditions: Physician Well-being|Cognitive Function|Diet Modification|Diet Habit|Shift-Work Related Sleep Disturbance|Sleep Deprivation
Interventions: OTHER: Dietary Modification
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Comparative Assessment of Intra-articular Knee Injections of Platelet-rich Plasma (PRP) and Hyaluronic Acid in the Treatment of Knee Osteoarthritis
Status: COMPLETED
Conditions: the Treatment of Knee Osteoarthritis
Interventions: DRUG: platelet-rich plasma|DRUG: durolane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: NEM® Versus Placebo in Exercised-induced Joint Pain, Stiffness, & Cartilage Turnover in Healthy Men & Women
Status: COMPLETED
Conditions: Exercise-induced Joint Pain|Exercise-induced Joint Stiffness|Exercise-induced Joint Cartilage Turnover
Interventions: DIETARY_SUPPLEMENT: NEM® brand eggshell membrane|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Administrating Oxytocin to Treat Treatment Schizophrenia and Schizo-affective Patients
Status: UNKNOWN
Conditions: Oxytocin + Non Specific Counselling|Oxytocin + Social Skills Training|Placebo + Non Specific Counselling|Placebo + Social Skills Training
Interventions: DRUG: Oxytocin|BEHAVIORAL: Social Skills Training|BEHAVIORAL: Placebo + Non Specific Counselling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Tolerability of MLC601 in Patients With Mild to Moderate Alzheimer Disease Who Were Unable to Tolerate or Failed to Benefit From Treatment With Rivastigmine
Status: COMPLETED
Conditions: Alzheimer Disease
Interventions: DRUG: MLC601
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study to Evaluate Safety and Efficacy of Combined Treatment With Ipilimumab and Intratumoral Interleukin-2
Status: COMPLETED
Conditions: Malignant Melanoma
Interventions: DRUG: Interleukin-2|DRUG: Ipilimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Online Behavior Change Intervention to Promote Physical Activity in Adults With Asthma
Status: COMPLETED
Conditions: Asthma|Sedentary Behavior|Physical Inactivity
Interventions: OTHER: Behavior change intervention|OTHER: Educational program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison Of Mackenzie Exercise Program Versus Routine Physical Therapy Management in Chronic Mechanical Neck Pain
Status: COMPLETED
Conditions: Neck Pain
Interventions: OTHER: Mckenzie exercise program|OTHER: Conventional Physical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Glycaemic and Insulinaemic Responses of Camel Milk
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: Camel milk|OTHER: camel milk powder solution|OTHER: raw cow milk|OTHER: Glucose solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Stem Cells Therapy for Corneal Blindness
Status: UNKNOWN
Conditions: Corneal Injuries|Corneal Burns|Corneal Scars and Opacities
Interventions: BIOLOGICAL: Ex-vivo cultivated limbal stem cell pool
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Interictal Epileptiform Activity on Some Cognitive Domains in Newly Diagnosed Epileptic Patients
Status: UNKNOWN
Conditions: Cognitive Impairment|Epilepsy
Interventions: DIAGNOSTIC_TEST: Digital electroencephalography (EEG) for an hour (16 channels)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Testing the Use of Combination Therapy in Patients With Persistent Low Level Acute Myeloid Leukemia (AML) Following Initial Treatment
Status: NOT_YET_RECRUITING
Conditions: Leukemia, Myeloid, Acute
Interventions: DRUG: Cytarabine|DRUG: Venetoclax|DRUG: CPX-351|DRUG: Azacitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Resection Versus Transcatheter Arterial Chemoembolization for Hepatocellular Carcinoma With Solitary Huge Tumor
Status: UNKNOWN
Conditions: Carcinoma, Hepatocellular|Survival Rate
Interventions: PROCEDURE: hepatic resection|PROCEDURE: TACE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of R932348 Ophthalmic Solution in Chronic Ocular Graft Versus Host Disease Patients(DROPS-2)
Status: COMPLETED
Conditions: Chronic Graft-versus-host Disease
Interventions: DRUG: R348 Ophthalmic Solution, 0.2%|DRUG: R348 Ophthalmic Solution, 0.5%|OTHER: Placebo Ophthalmic Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Peripheral Microcirculation Hemodynamics Following Various Changes Based on Noninvasive Thermography
Status: COMPLETED
Conditions: Microcirculation
Interventions: DEVICE: Omnilux new-U (Red LED)|DEVICE: Omnilux new-U (Near infrared LED)|DEVICE: RESPeRATE|DEVICE: Heating bag
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: An RCT Comparing Xenograft and Allograft for Ridge Preservation
Status: COMPLETED
Conditions: Tooth Loss
Interventions: DEVICE: allograft + x-link collagen membrane|DEVICE: xenograft + non-x-link collagen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Dose-Finding and Exploratory Study of RO5323441 in Combination With Sorafenib in Patients With Hepatocellular Carcinoma
Status: COMPLETED
Conditions: Carcinoma, Hepatocellular
Interventions: DRUG: RO5323441|DRUG: RO5323441|DRUG: sorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Triazolam and Midazolam for Anxiolysis During Dental Treatment in the Pediatric Patient
Status: COMPLETED
Conditions: Dental Anxiety
Interventions: DRUG: Midazolam Hydrochloride 2Mg/mL Syrup|DRUG: Triazolam 0.125 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Dipole Density Mapping in Supraventricular Tachycardia
Status: COMPLETED
Conditions: Supraventricular Tachycardia
Interventions: DEVICE: Dipole Density Mapping with AcQMap followed by ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparing Three Different Doses of Intrathecal Ketamine
Status: COMPLETED
Conditions: Ketamine Causing Adverse Effects in Therapeutic Use
Interventions: DRUG: Ketamine 0.1 mg|DRUG: Ketamine 0.2 mg|DRUG: Ketamine 0.3 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Dornase Alpha Versus Hypertonic Saline for Lung Atelectasis in Non-Cystic Fibrosis Patients
Status: COMPLETED
Conditions: Atelectasis
Interventions: DRUG: Normal saline:|DRUG: Hypertonic Saline|DRUG: Dornase alpha
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Social and Moral Cognition in Multiple Sclerosis
Status: RECRUITING
Conditions: Multiple Sclerosis
Interventions: OTHER: Socio-demographic questionnaire, moral judgment task, cognitive tests, psychoaffective assessment|OTHER: MS questionnaire|OTHER: MONTREAL COGNITIVE ASSESSMENT (MoCA) test
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: TBI Care: Collaborative Care for Pain After Traumatic Brain Injury (TBI)
Status: COMPLETED
Conditions: Brain Injuries, Traumatic|Chronic Pain|Post-Traumatic Headache
Interventions: BEHAVIORAL: Collaborative Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PTP1B Implication in the Vascular Dysfunction Associated With Obstructive Sleep Apnea
Status: COMPLETED
Conditions: Sleep Apnea|Inflammation|Atherosclerosis
Interventions: OTHER: myeloid PTP1B expression analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Preemptive Oral Gabapentin and Tramadol on Postoperative Pain After Knee Arthroscopy
Status: NOT_YET_RECRUITING
Conditions: Gabapentin|Tramadol|Postoperative Pain|Knee Arthroscopy|Spinal Anesthesia
Interventions: DRUG: Gabapentin|DRUG: Tramadol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Combination Study With Soluble LAG-3 Fusion Protein Eftilagimod Alpha (IMP321) and Pembrolizumab in Patients With Previously Untreated Unresectable or Metastatic NSCLC, or Recurrent PD-X Refractory NSCLC or With Recurrent or Metastatic HNSCC
Status: ACTIVE_NOT_RECRUITING
Conditions: NSCLC|HNSCC
Interventions: DRUG: Eftilagimod alpha|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cardiac Index and General Anesthesia Without Opioid.
Status: RECRUITING
Conditions: Hip Arthropathy|Hip Disease
Interventions: DRUG: Dexmedetomidine|DRUG: Sufentanil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Methylation Status of BDNF Gene After Dialectical Behavior Therapy in BPD
Status: COMPLETED
Conditions: Borderline Personality Disorder
Interventions: BEHAVIORAL: Dialectical behavior therapy|OTHER: Treatment as Usual: any other drug or psychotherapy offered to participants, except DBT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: An Evaluation of the Pharmacokinetics and Pharmacodynamics of Oral Dabigatran Etexilate in Hemodialysis Patients
Status: COMPLETED
Conditions: Blood Coagulation Disorders
Interventions: DRUG: Dabigatran Etexilate 110 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Hyperthermia As A Conservative Treatment For Carpal Tunnel Syndrome. A Randomized "Sham" Controlled Trial
Status: COMPLETED
Conditions: Carpal Tunnel Syndrome
Interventions: OTHER: group A: HYPERTHERMIA|OTHER: No intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of CTAP101 Capsules on Ca/iPTH in Advanced Breast/Prostate Cancer Patients Treated With Denosumab/Zoledronic Acid
Status: COMPLETED
Conditions: Breast Cancer|Prostate Cancer|Bone Neoplasms|Hypocalcemia|Hyperparathyroidism, Secondary
Interventions: DRUG: CTAP101 Capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effectiveness of SMS Reminders on Influenza Vaccination Coverage in Patients With RA in the ART Registry
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: OTHER: sms and emails reminders|OTHER: No reminders
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Novel Individualized Connectome-guided Approach for Precision Intermittent Theta Burst Stimulation for Depression
Status: RECRUITING
Conditions: Depression
Interventions: DEVICE: Beam F3 targeted accelerated iTBS|DEVICE: Individualized connectome-guided accelerated iTBS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Pelvic Floor Muscle Training With Stabilization Exercises With Various Intensity in Women With Stress Urinary Incontinence
Status: COMPLETED
Conditions: Stress Urinary Incontinence
Interventions: OTHER: Pelvic Floor Muscle Training (PFMT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Home-based Intervention to Promote Mindful Breathing Awareness Through Pursed-lip Breathing Training for COPD Patients
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: BEHAVIORAL: Mindful Breathing|BEHAVIORAL: Home-Based Pulmonary Rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Omega-3 Polyunsaturated Fatty Acids on Major Depressive Disorder in Patients With Cardiovascular Diseases
Status: COMPLETED
Conditions: Cardiovascular Diseases|Major Depressive Disorder
Interventions: DIETARY_SUPPLEMENT: n-3 Polyunsaturated fatty acid|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Smile-Kids: Study on Complementary Feeding Transition
Status: COMPLETED
Conditions: Infant|Health Promotion|Nursery|Educators
Interventions: BEHAVIORAL: Intervention taught by trained educators
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Clinical & Radiographical Evaluation of the Effect of Dycal & Biodentine in DPC in Primary Teeth
Status: COMPLETED
Conditions: Dental Pulp Exposure
Interventions: PROCEDURE: Direct Pulp Capping using Dycal and Biodentine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Diagnostic Procedures in Detecting Tumor Cells in the Bone Marrow of Patients Undergoing Surgery for Stage I, Stage II, or Stage IIIA Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: PROCEDURE: Bone Marrow Aspiration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety and Neuroprotective Effects of Polyphenon E in MS; Phase II
Status: TERMINATED
Conditions: Multiple Sclerosis
Interventions: DRUG: Polyphenon E|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Effects of Supplementation With Ergocalciferol on Erythropoietin Dosing in Hemodialysis Patients
Status: COMPLETED
Conditions: End Stage Renal Disease
Interventions: DIETARY_SUPPLEMENT: ergocalciferol supplementation|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Extended Cross-sectoral Nurse Follow-up After Discharge From a Geriatric Ward - Benefits and Challenges. A Mixed-method Study
Status: NOT_YET_RECRUITING
Conditions: Extended Cross-sectoral Nurse Follow-up After Discharge From a Geriatric Ward
Interventions: PROCEDURE: geriatric follow-up home visit after discharge
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Efficacy and Safety of Omalizumab in Refractory Chronic Spontaneous Urticaria Patients
Status: COMPLETED
Conditions: Chronic Spontaneous Uriticaria
Interventions: BIOLOGICAL: Omalizumab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Montelukast in Reducing the Incidence and Severity of Monoclonal Antibodies Associated Infusion Reactions
Status: RECRUITING
Conditions: Infusion Reaction|Monoclonal Antibody
Interventions: DRUG: Montelukast 10 Mg Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study to Assess the Relationship Between Daily Dosing of NRPT and Changes in Liver Fat in Healthy Volunteers
Status: COMPLETED
Conditions: Fatty Liver
Interventions: DIETARY_SUPPLEMENT: Group 1 NRPT|DIETARY_SUPPLEMENT: Group 2 NRPT|OTHER: Group 3 Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: TAP vs Surgical Infiltration of Local Anesthetic in Laparoscopic and Robotic Hysterectomy
Status: COMPLETED
Conditions: Acute Pain
Interventions: DRUG: Liposomal Bupivacaine|DRUG: Bupivacaine|DEVICE: Ultrasound|DRUG: Epinephrine|DRUG: acetaminophen|DRUG: ibuprofen|DRUG: Oxycodone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cuevas Medek Exercises on Balance and Postural Control in Children With Spastic Cerebral Palsy
Status: COMPLETED
Conditions: Spastic Cerebral Palsy
Interventions: OTHER: CUEVAS MEDEK EXERCISES|OTHER: BALANCE AND POSTURAL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Efficacy and Safety Study of Ustekinumab in Participants With Active Nonradiographic Axial Spondyloarthritis
Status: TERMINATED
Conditions: Nonradiographic Axial Spondylitis, Ankylosing
Interventions: DRUG: Group 1: Placebo|DRUG: Group 2: Ustekinumab 45 mg|DRUG: Group 3: Ustekinumab 90 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Dexmedetomidin and Remifentanil for the Effect on Airway Reflex and Hemodynamic Response During Emergence in Patients Undergoing Craniotomy
Status: COMPLETED
Conditions: Open Craniotomy
Interventions: DRUG: remifentanil|DRUG: dexmedetomidine with remifentanil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Lidocaine and Tetracaine Cream to Treat Postherpetic Neuralgia (PHN)
Status: COMPLETED
Conditions: Postherpetic Neuralgia
Interventions: DRUG: lidocaine and tetracaine cream 7%/7%|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Analysis of Cardiac Biomarkers, ECG and CPET Results in Children With Cardiomyopathies
Status: UNKNOWN
Conditions: Cardiomyopathies
Interventions: DIAGNOSTIC_TEST: ECG|DIAGNOSTIC_TEST: 24-hour ECG monitoring|DIAGNOSTIC_TEST: Cardio-pulmonary exercise test (CPET)|DIAGNOSTIC_TEST: Cardiac biomarkers
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Cross Pin Configurations in Supracondylar Humerus Fracture Treatment: 2 Pins Versus 3 Pins
Status: COMPLETED
Conditions: Supracondylar Humerus Fracture
Interventions: PROCEDURE: crossed pin configuration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Additional Neurodynamic Intervention in Patients With Chronic Ankle Instability
Status: RECRUITING
Conditions: Ankle Sprains
Interventions: OTHER: balance training alone|OTHER: balance training and neurodynamic intervention for the common peroneal nerve
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Liberalization of Visiting Policies in ICU for Reducing High Risk of Post-traumatic Stress Disorder
Status: COMPLETED
Conditions: PTSD in Family Members of ICU Patients
Interventions: OTHER: Visiting policies: 24 hours a day, 7 days a week|OTHER: Restriction of visiting policies < 6 hours
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Dexmedetomidine Combined With Lidocaine Infusion Affect PONV
Status: COMPLETED
Conditions: Lidocaine|Dexmedetomidine|Nausea and Vomiting, Postoperative
Interventions: DRUG: lidocaine and dexmedetomidine infusion|DRUG: Saline infusion|DRUG: Lidocaine infusion|DRUG: Dexmedetomidine infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Sustained Effect of Droxidopa in Symptomatic Neurogenic Orthostatic Hypotension
Status: COMPLETED
Conditions: Symptomatic Neurogenic Orthostatic Hypotension
Interventions: DRUG: Droxidopa capsules|DRUG: Placebo capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT