pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Immunotherapy Combined With Capecitabine Versus Capecitabine Monotherapy in Advanced Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer
Interventions: BIOLOGICAL: DC-CIK Immunotherapy|DRUG: Capecitabine Monotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dexamethasone Before Elective Cesarean Section at Term in Reducing Neonatal Respiratory Distress Syndrome
Status: UNKNOWN
Conditions: C08.381.840.500.475|C08.381.840.500.737
Interventions: DRUG: Dexamethasone phosphate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: VIBRANT Study of Vurolenatide in Adult Patients With Short Bowel Syndrome.
Status: TERMINATED
Conditions: Short Bowel Syndrome
Interventions: DRUG: Vurolenatide 50mg/PBO|DRUG: Vurolenatide 100mg/PBO|DRUG: Vurolenatide 50/50 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Aspects of Self-harm - Cognition, Imaging and Treatability
Status: RECRUITING
Conditions: Self-Harm, Deliberate|Non-Suicidal Self Injury|Attempt Suicide|Personality Disorders
Interventions: DIAGNOSTIC_TEST: Emotional Stop Signal Task|DIAGNOSTIC_TEST: Magnetic Resonance Imaging|OTHER: World Health Organizations Disability Assessment Schedule (WHODAS 2.0)|DIAGNOSTIC_TEST: Personality Inventory for DSM-5 (PID-5)|DIAGNOSTIC_TEST: Stop Signal Task (CANTAB)|DIAGNOSTIC_TEST: Intra-Extra Dimensional Set Shift (CANTAB)|DIAGNOSTIC_TEST: Spatial Working Memory Test (CANTAB)|DIAGNOSTIC_TEST: Multitasking Test (CANTAB)|DIAGNOSTIC_TEST: Cambridge Gambling Task Test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Umbilical Cord Plasma for Treating Endometrial Pathologies (Thin Endometrium / Asherman's Syndrome/ Endometria Atrophy)
Status: RECRUITING
Conditions: Asherman Syndrome|Endometrial Atrophy
Interventions: PROCEDURE: Injection of hUC-PRP by hysteroscopy|DRUG: Oestraclin|PROCEDURE: Umbilical cord blood collection|PROCEDURE: Endometrial biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Silver Foam Dressing Superior to Porcine Xenograft in Pediatric Scalds
Status: COMPLETED
Conditions: Burns Scald
Interventions: OTHER: Porcine xenograft (wound dressings)|OTHER: Silver foam (wound dressings)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Motexafin Gadolinium in Treating Patients With Glioblastoma Multiforme Who Are Undergoing Radiation Therapy to the Brain
Status: COMPLETED
Conditions: Brain and Central Nervous System Tumors
Interventions: DRUG: motexafin gadolinium|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Efficacy and Safety of Fixed Dose Combination of Diphenhydramine + Pseudoephedrine + Dropropizine in the Control of Cough and the Relief of Nasal Symptoms, Suffering From Non-productive Cough and Acute Rhinitis
Status: WITHDRAWN
Conditions: Nasal Congestion|Cough
Interventions: DRUG: Group 1|DRUG: Group 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Smoking and Chlorhexidine on Periodontal Tissues After Non- Surgical Periodontal Therapy in Patients With Periodontitis
Status: ACTIVE_NOT_RECRUITING
Conditions: Smoking|Periodontitis|Periodontal Diseases
Interventions: PROCEDURE: non surgical periodontal therapy|DRUG: Chlorhexidine mouthwash
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Web-based Decision Aid Tool for Prostate Cancer Patients
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: OTHER: Interviews|OTHER: Treatmentchoice Decisional Tool|OTHER: Questionnaires|OTHER: Interviews with stakeholders
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Post-market Prospective, Multicenter, Randomized and Single-blinded Clinical Investigation to Evaluate Whether Cardiac Re-Synchronization Therapy (CRT) Using Automatic Continuous Atrioventricular (AV) Delay Optimization is Superior to CRT With Conventional Biventricular Stimulation (BiV).
Status: NOT_YET_RECRUITING
Conditions: Heart Failure
Interventions: DEVICE: SyncAV function on
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Respiratory Mechanics Assessment at Different Head of the Bed Elevations in Mechanically Ventilated Patients
Status: RECRUITING
Conditions: Respiratory Failure|Pulmonary Disease
Interventions: OTHER: Sequencial increasing of head of the bed elevation and alveolar recruitment maneuver followed by a PEEP titration with 10° of head of the elevation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Optimal Length of Progesterone Supplementation Before the Transfer of Cryopreserved(Frozen)-Thawed Embryos in an Artificial Cycle With Exogenous Estrogen and Progesterone.
Status: COMPLETED
Conditions: Cryopreservation|Embryo Implantation|Progesteron
Interventions: DRUG: Progesterone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Survivorship Booklets With or Without Individual Telephone Sessions in Increasing Knowledge About the Impact of Breast Cancer in African American and Latina Breast Cancer Survivors
Status: COMPLETED
Conditions: Breast Cancer|Cancer Survivor|Psychosocial Effects of Cancer and Its Treatment
Interventions: BEHAVIORAL: telephone-based intervention|OTHER: counseling intervention|OTHER: educational intervention|OTHER: questionnaire administration|PROCEDURE: psychosocial assessment and care|PROCEDURE: quality-of-life assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Expanded Indications in the MED-EL Pediatric Cochlear Implant Population
Status: COMPLETED
Conditions: Hearing Loss, Sensorineural
Interventions: DEVICE: MED-EL SYNCHRONY PIN Cochlear Implant|OTHER: Cochlear Implant
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Research Study To See How Well an Eye Drop, SURF-100 (A Mycophenolic Acid/Betamethasone Sodium Phosphate Combination), Works and What Side Effects There Are in Subjects With Dry Eye Disease
Status: COMPLETED
Conditions: Dry Eye Disease
Interventions: DRUG: SURF-100 (Combination of 0.3% Mycophenolic Acid and 0.01% Betamethasone Sodium Phosphate)|DRUG: Mycophenolic Acid 0.1%|DRUG: Mycophenolic Acid 0.3%|DRUG: Betamethasone Sodium Phosphate 0.01%|DRUG: Placebo Comparator: Vehicle|DRUG: Cyclosporine 0.05% Ophthalmic Emulsion|DRUG: Lifitegrast 5% Ophthalmic Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Predictors of AAA Expansion and/or Rupture
Status: TERMINATED
Conditions: Abdominal Aortic Aneurysm (AAA)
Interventions: DRUG: Assess AAA rupture risk by PET-CTA scans|DRUG: 18F-fludeoxyglucose (FDG)|DIAGNOSTIC_TEST: 11C-PBR28
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Reducing Eye Strain and Anxiety Using a Digital Intervention During Online Learning Class Recess Among Children at Home: A Randomized Controlled Trial
Status: COMPLETED
Conditions: Anxiety|Digital Eye Strain
Interventions: BEHAVIORAL: Digital intervention|BEHAVIORAL: Information-only intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase II, Single-Arm Trial of Poziotinib as Salvage Treatment in Patients With Metastatic Breast Cancer Who Has HER2 or EGFR Mutation or Activated AR or EGFR Pathway
Status: COMPLETED
Conditions: Metastatic Breast Cancer
Interventions: DRUG: Poziotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Salvage Chemotherapy (R-ESHAP) to Treat Relapsed and Refractory Aggressive Non-Hodgkin's Lymphoma
Status: TERMINATED
Conditions: Lymphoma, Non-Hodgkin
Interventions: DRUG: Rituximab, Etoposide, Methylprednisolone, Cytarabine, Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prepectoral and Subpectoral Implant-based Breast Reconstruction
Status: UNKNOWN
Conditions: Breast Carcinoma|Breast Reconstruction
Interventions: PROCEDURE: prepectoral implant-based reconstruction|PROCEDURE: subpectoral implant-based reconstruction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Use of PUL-042 Inhalation Solution to Reduce the Severity of COVID-19 in Adults Positive for SARS-CoV-2 Infection
Status: COMPLETED
Conditions: COVID-19
Interventions: DRUG: PUL-042 Inhalation Solution|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of a 2-week Sugar Stress on Bacterial Profiles in Whole Saliva
Status: COMPLETED
Conditions: Dental Caries|Gingivitis
Interventions: DIETARY_SUPPLEMENT: Succrose rinsing|DIETARY_SUPPLEMENT: Probiotic lozenges|OTHER: xylitol rinsing|OTHER: Placebo tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Self-acupressure for Insomnia in Perimenopausal Women
Status: NOT_YET_RECRUITING
Conditions: Insomnia|Perimenopausal Women
Interventions: BEHAVIORAL: Self-Administered Acupressure Group|BEHAVIORAL: Sleep Hygiene Education group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Novel Wearable Device for the Treatment of Insomnia
Status: COMPLETED
Conditions: Insomnia
Interventions: DEVICE: Sleep Wellness Device (BeCurie)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: IASTM Versus PRT in Patients With Chronic PF
Status: COMPLETED
Conditions: Chronic Plantar Fasciitis
Interventions: OTHER: Instrument assisted soft tissue mobilization in addition to traditional treatment|OTHER: Positional release technique in addition to traditional treatment|OTHER: Traditional treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A 6-Week Study to Evaluate the Photoallergic Potential of Diacerein 1% Ointment in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Diacerein 1% ointment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of Risperidone Long-Acting Injection Versus Oral Antipsychotics in Schizophrenia Participants With a History of Being Poorly Compliant With Taking Their Medication
Status: TERMINATED
Conditions: Schizophrenia
Interventions: DRUG: Risperidone long-acting injection (LAI)|DRUG: Oral atypical Antipsychotic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Therapeutic Magnetic Resonance Imaging (MRI)-Guided High Intensity Focused Ultrasound (HIFU) Ablation of Uterine Fibroids
Status: COMPLETED
Conditions: Uterine Fibroids
Interventions: DEVICE: Philips MRI-guided HIFU system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Safety and Efficacy of ABT-122 Given With Methotrexate in Subjects With Active Rheumatoid Arthritis Who Have an Inadequate Response to Methotrexate
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: BIOLOGICAL: adalimumab|BIOLOGICAL: ABT-122
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase IIa Study of Copanlisib in Relapsed or Refractory Mantle Cell Lymphoma (MCL)
Status: TERMINATED
Conditions: Lymphoma, Mantle-Cell
Interventions: DRUG: Copanlisib (BAY80-6946)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cell-Free DNA and RNA in Blood fromMetastatic Prostate Cancer Patients
Status: TERMINATED
Conditions: Hormone-Resistant Prostate Cancer|Metastatic Prostate Carcinoma|Prostate Adenocarcinoma
Interventions: OTHER: Cytology Specimen Collection Procedure|OTHER: Laboratory Biomarker Analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Efficacy of Three Different Limus Agent-Eluting Stents to Prevent Restenosis
Status: COMPLETED
Conditions: Coronary Disease
Interventions: DEVICE: Rapamycin-eluting Stent|DEVICE: Zotarolimus-eluting Stent|DEVICE: Rapamycin-eluting Stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Mobilization and Ozone Therapy in Impingement Syndrome
Status: RECRUITING
Conditions: Impingement Syndrome
Interventions: OTHER: Ozone therapy|OTHER: Mulligan Mobilization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Improving Glycemic Control With Electrical Stimulation in Mexican-Americans
Status: RECRUITING
Conditions: Obesity|Overweight|Insulin Resistance
Interventions: DEVICE: Neuromuscular Electrical Stimulation (Sensory)|DEVICE: Neuromuscular Electrical Stimulation|OTHER: Resistance Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Fermented Grape Combined With Fruits and Vegetables Drink on Anti-aging and Anti-inflammatory
Status: COMPLETED
Conditions: Skin Condition
Interventions: DIETARY_SUPPLEMENT: placebo group|DIETARY_SUPPLEMENT: fermented grape drinks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial for Prevention of Loss of the Effect of Biological Drugs in Patients With Inflammatory Bowel Disease
Status: UNKNOWN
Conditions: Inflammatory Bowel Diseases
Interventions: DEVICE: An App for reminding patients to take their medication
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: A Phase Ib/II Study of AK112 in Combination With AK117 in Advanced Malignant Tumors
Status: UNKNOWN
Conditions: Advanced Malignant Tumors
Interventions: DRUG: AK112|DRUG: AK117|DRUG: Carboplatin|DRUG: Cisplatin|DRUG: 5-Fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PET Imaging With Cu-64 Labeled Trastuzumab in HER2+ Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: RADIATION: PET Imaging With Cu-64 Labeled Trastuzumab|RADIATION: PET Imaging With Cu-64 Labeled Trastuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Mindfulness Based Intervention (MBI) on the Quality of Life and Non-Motor Symptoms (NMS) of Persons With PD
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: BEHAVIORAL: Mindfulness Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: FR901228 in Treating Patients With Metastatic Breast Cancer
Status: COMPLETED
Conditions: Male Breast Cancer|Recurrent Breast Cancer|Stage IV Breast Cancer
Interventions: DRUG: romidepsin|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Functional Vision With ACRYSOF® IQ IOLs Blue Light Filtration
Status: COMPLETED
Conditions: Cataract
Interventions: DEVICE: Clear clip-on glasses|DEVICE: Blue light filter clip-on glasses|DEVICE: ACRYSOF® IQ IOL|DEVICE: Clear IOL
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: Envafolimab as Neoadjuvant Immuntherapy in Resectable Local Advanced dMMR/MSI-H Colorectal Cancer
Status: RECRUITING
Conditions: Colorectal Cancer|Mismatch Repair-deficient (dMMR)|Microsatellite Instability-high (MSI-H)|Neoadjuvant Therapy
Interventions: DRUG: Neoadjuvant therapy with PD-L1 inhibitor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Patient Adherence to Premarin Versus Vagifem Therapy After Female Pelvic Reconstructive Surgery
Status: WITHDRAWN
Conditions: Estrogen|Menopause|Pelvic Floor Disorders|Surgery
Interventions: DRUG: Premarin|DRUG: Vagifem
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Detection of Clinically Significant Prostate Cancer Using Transperineal Targeted Biopsy Compared to Standard Transrectal Biopsy
Status: COMPLETED
Conditions: Prostate Cancer|Magnetic Resonance Imaging|Target Lesion|Fusion Biopsy|Clinically Significant Prostate Cancer|Transperineal
Interventions: DEVICE: MRI/ultrasound transperineal prostate biopsy|DEVICE: transrectal ultrasound-guided prostate biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Women's Health Project for Women Wanting to Lose Weight
Status: COMPLETED
Conditions: Obesity
Interventions: BEHAVIORAL: Diet and exercise counseling|BEHAVIORAL: Diet, exercise, sleep hygiene counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Surgical Versus Conservative Treatment of Acute Mallet Fingers; a Randomised Controlled Trial
Status: WITHDRAWN
Conditions: Finger Injury
Interventions: PROCEDURE: extensor tendon repair|PROCEDURE: Mallet splint for 4 weeks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diabetes Intervention Trial With Vitamin D in Subjects of Nordic and Sub-Indian Ethnicity
Status: UNKNOWN
Conditions: Diabetes Mellitus Type 2|Hypovitaminosis D
Interventions: DRUG: Cholecalciferol|OTHER: Orange juice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Erector Spinae Block Using a Dexmedetomidine Versus Magnesium Sulfate as an Adjuvant to Bupivacaine
Status: COMPLETED
Conditions: Postoperative Analgesia
Interventions: PROCEDURE: Erector spinae block using bupivacaine 0.25% and magnesium sulfate|PROCEDURE: Erector spinae block using bupivacaine and dememdetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lipidome and Microbiome Profile of the Eye in Rosacea
Status: COMPLETED
Conditions: Rosacea|Ocular Rosacea|Cutaneous Rosacea
Interventions: DRUG: Doxycycline
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effects of Different Antirheumatic Treatments of Arthritis on Antibody Response Following Vaccination Using Prevenar®
Status: COMPLETED
Conditions: Rheumatoid Arthritis|Spondylarthropathy
Interventions: BIOLOGICAL: Prevenar vaccination
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Respiratory and Hemodynamics Parameters Response to Positive End-Expiratory Pressure
Status: COMPLETED
Conditions: Obesity Associated Disorder
Interventions: DEVICE: respiratory parameters on mechanical ventilator (PEEP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Ezetimibe Plus Simvastatin Versus Simvastatin Alone on Atherosclerosis in the Carotid Artery (ENHANCE)(P02578)
Status: COMPLETED
Conditions: Atherosclerosis|Hypercholesterolemia|Hyperlipoproteinemia Type II
Interventions: DRUG: ezetimibe (plus simvastatin)|DRUG: placebo (plus simvastatin)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Prevention of Myocardial Injury in Non-cardiac Surgery
Status: COMPLETED
Conditions: Myocardial Injury|Myocardial Infarction
Interventions: PROCEDURE: Remote ischemic preconditioning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Protocol-Specified Modification of Immunosuppression Directed to Protocol Biopsy in Kidney Transplantation
Status: UNKNOWN
Conditions: Surveillance Protocol Biopsy
Interventions: PROCEDURE: Surveillance protocol kidney allograft biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Next-Day Residual Effects of Gabapentin, Diphenhydramine and Triazolam on Simulated Driving Performance in Normal Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Gabapentin|DRUG: Diphenhydramine citrate|DRUG: Triazolam|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Subcutaneous TAK-079 Added to Standard of Care Regimens in Participants With Newly Diagnosed Multiple Myeloma (NDMM)
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: TAK-079|DRUG: Lenalidomide|DRUG: Dexamethasone|DRUG: Bortezomib|DRUG: Pomalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TeenPower: e-Empowering Teenagers to Prevent Obesity
Status: COMPLETED
Conditions: Adolescent Obesity|Empowerment|ICT
Interventions: BEHAVIORAL: Structured school based intervention|DEVICE: mobile app usage
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Lirilumab With Rituximab for Relapsed, Refractory or High-risk Untreated Chronic Lymphocytic Leukemia (CLL) Patients
Status: COMPLETED
Conditions: Leukemia|Chronic Lymphocytic Leukemia|Lymphocytic Leukemia
Interventions: DRUG: Lirilumab|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transpulmin Suppository and Guaiacol Compared to Transpulmin Syrup in Pediatric Participants With Productive Cough
Status: TERMINATED
Conditions: Cough
Interventions: DRUG: Transpulmin suppository|DRUG: Guaiacol suppository|DRUG: Transpulmin syrup
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of the Skin-concentration of Vildagliptin 50 mg Every 12 Hours for 10 Days in Healthy Subjects and Patients With Type 2 Diabetes
Status: TERMINATED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Vildagliptin|DRUG: Vildagliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Glycemic and Insulinemic Index Determination of Two Products: Fructilight® and A Fruit Fructo-Oligosaccharides in Sweet Matrix
Status: UNKNOWN
Conditions: Healthy
Interventions: OTHER: Glycemic and insulinemic index tests of a fruit fructose syrup and a fruit fructo-oligosaccharid syrup
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Sourdough Fermented Rye Crisp Bread on Appetite and Postprandial Metabolic Responses
Status: COMPLETED
Conditions: Appetite
Interventions: OTHER: refined wheat crisp bread|OTHER: sourdough fermented rye crisp bread|OTHER: unfermented rye crisp bread
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: A Short Metaphyseal Fitting Total Hip Arthroplasty in Young and Elderly Patients
Status: COMPLETED
Conditions: Osteonecrosis|Osteoarthritis
Interventions: DEVICE: Total Hip Arthroplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Prospective, Multicenter, Randomized Control Study To Determine Clinical Effectiveness, Patient Wellness and Cost of Pain Related Care of In-Elastic Lumbar Sacral Orthoses Versus Standard Medical Treatment in Patients Presenting With Acute Low Back Pain In Primary Care Centers (The ARREST Study)
Status: TERMINATED
Conditions: Back Pain|Low Back Pain
Interventions: DEVICE: Aspen Horizon 627 LSO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mechanisms of Rumination Change in Adolescent Depression
Status: RECRUITING
Conditions: Major Depressive Disorder|Mood Disorders
Interventions: BEHAVIORAL: Rumination-Focused CBT|BEHAVIORAL: Relaxation-based Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Romiplostim in Combination With CsA vs. CsA in the Treatment of Newly Diagnosed NSAA
Status: NOT_YET_RECRUITING
Conditions: Non Severe Aplastic Anemia
Interventions: DRUG: Romiplostim|DRUG: Ciclosporin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study of Linperlisib (YY-20394) in Patients With Relapsed or Refractory Peripheral T/NK Cell Lymphoma
Status: UNKNOWN
Conditions: Peripheral T/NK Cell Lymphoma (R/R PTCL)
Interventions: DRUG: YY-20394
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Significance of Pre-interventional Optical Coherence Tomography in Bioresorbable Vascular Scaffold Implantation
Status: TERMINATED
Conditions: Myocardial Ischemia
Interventions: DEVICE: Angiography-guided PCI with BVS|DEVICE: Optical coherence tomography-guided PCI with BVS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exploration of Gait Biomechanics and Muscle Pain of the Lower Extremity
Status: RECRUITING
Conditions: Pain, Acute
Interventions: OTHER: Hypertonic saline injection|OTHER: Isotonic saline injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Ethanol and Cannabinoid Effects on Simulated Driving and Related Cognition: Sub-Study II
Status: ACTIVE_NOT_RECRUITING
Conditions: Cannabis|Alcohol Effect|Driving Under the Influence of Alcohol and Other Drugs
Interventions: DRUG: Active inhaled cannabis|DRUG: Placebo|DRUG: Active Oral Ethanol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Assess the Efficacy and Safety of PPC-06 (Tepilamide Fumarate)
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: PPC-06 400 mg QD|DRUG: PPC-06 400 mg BID|DRUG: PPC-06 600 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Behavioral Intervention on Cannabinoid Receptors in BAD
Status: UNKNOWN
Conditions: Bipolar Affective Disorder, Currently in Remission|Bipolar Disorder I|Bipolar Disorder II
Interventions: BEHAVIORAL: Wim Hof method
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Five-year Patency of No-touch Saphenous Vein Grafts in On-pump Versus Clamp-less Off-pump Coronary Artery Bypass Surgery
Status: COMPLETED
Conditions: Coronary Artery Stenoses
Interventions: PROCEDURE: The use of extracorporeal circulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effect of Dupilumab on Exercise Capacity in Adult Patients With Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: dupilumab|DRUG: Matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Denosumab Treatment in CKD Patients at High Risk of Fracture
Status: RECRUITING
Conditions: Chronic Kidney Diseases|Fracture|Bone Density, Low|End Stage Renal Disease
Interventions: DRUG: Denosumab|DRUG: Non-denosumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Performance of Different Resin Infiltration Materials on White Spot Lesions: Clinical and Laboratory Assessments
Status: UNKNOWN
Conditions: White Spot Lesion
Interventions: OTHER: Icon® resin infiltration|OTHER: MI paste plus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Reinforced PTFE Meshes Versus Customized Titanium Meshes
Status: ACTIVE_NOT_RECRUITING
Conditions: Surgical Procedure, Unspecified|Soft Tissue Infections|Surgical Wound Dehiscence|Bone Density|Bone Loss|Dental Implant Failed
Interventions: DEVICE: RPM - Osteogenics Lubbock Texas USA|DEVICE: Yxoss CBR - Reoss Filderstadt Germany
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Placebo-Controlled Trial of Pregabalin (Lyrica) for Irritable Bowel Syndrome
Status: COMPLETED
Conditions: Irritable Bowel Syndrome
Interventions: DRUG: Pregabalin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: GLP-1 Analogue Effects on Food Cues, Stress, Motivation for Highly Palatable Foods, and Weight
Status: RECRUITING
Conditions: Obesity
Interventions: DRUG: GLP-1 analogue - semaglutide|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cosmetic Outcomes With Tissue Adhesive (2-octylcyanoacrylate) or Staples in Repeated Cesarean Section
Status: COMPLETED
Conditions: Cesarean Section
Interventions: PROCEDURE: Staples|PROCEDURE: Tissue adhesive
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Individualization of the Immunological Risk Based on Selective Biomarkers in Living-donor Renal Recipients
Status: UNKNOWN
Conditions: Kidney Transplant Failure and Rejection
Interventions: DIAGNOSTIC_TEST: biomarkers driven immunosuppressive therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Single-Arm Phase II Study of Neoadjuvant Intensified Androgen Deprivation (Leuprolide and Abiraterone Acetate) in Combination With AKT Inhibition (Capivasertib) for High-Risk Localized Prostate Cancer With PTEN Loss
Status: RECRUITING
Conditions: High-Risk Prostate Cancer
Interventions: DRUG: Capivasertib|DRUG: abiraterone acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rivaroxaban in Combination With Aspirin Alone or With Aspirin and a Thienopyridine in Patients With Acute Coronary Syndromes (The ATLAS ACS TIMI 46 Trial)
Status: COMPLETED
Conditions: Acute Coronary Syndrome
Interventions: DRUG: Rivaroxaban/Placebo|DRUG: Placebo|DRUG: Rivaroxaban
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Total Intravenous Anesthesia With Remifentanil-propofol Admixture
Status: COMPLETED
Conditions: Total Intravenous Anesthesia|Propofol|Remifentanil|Bispectral Index Monitoring
Interventions: COMBINATION_PRODUCT: Remifentanil-Propofol admixture
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of 4-week Dihydrocapsiate Ingestion on Resting Metabolic Rate
Status: COMPLETED
Conditions: Obesity|Weight
Interventions: OTHER: Dihydrocapsiate|OTHER: Dihydrocapsiate|OTHER: Dihydrocapsiate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of cVATS Segmentectomy Versus Lobectomy for Lung Adenocarcinoma in Situ and With Microinvasion
Status: UNKNOWN
Conditions: Non-small Cell Lung Cancer Stage I|Lung Adenocarcinoma
Interventions: PROCEDURE: patients undergo cVATS segmentectomy|PROCEDURE: Patients undergo cVATS lobectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transition of Adolescents and Young Adults With Diabetes From Pediatric to Adult Care
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: BEHAVIORAL: Transition Social Behavioral Intervention|BEHAVIORAL: Diabetes Transition Clinic
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating the Efficacy, Safety, and Reliability of Vardenafil
Status: COMPLETED
Conditions: Erectile Dysfunction
Interventions: DRUG: Levitra (Vardenafil, BAY38-9456)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Letermovir-based Dual Therapy for Treatment of Cytomegalovirus Infections
Status: NOT_YET_RECRUITING
Conditions: Cytomegalovirus Infection
Interventions: DRUG: Letermovir|DRUG: Valganciclovir|DRUG: Letermovir placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Focus Extracorporeal Shock Wave Therapy on Hamstring Tightness
Status: COMPLETED
Conditions: Hamstring Tightness
Interventions: DEVICE: focus extracorporeal shock wave therapy|BEHAVIORAL: Home stretching program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Temozolomide and Radiation Therapy in Treating Young Patients With Pontine Glioma
Status: UNKNOWN
Conditions: Brain and Central Nervous System Tumors
Interventions: DRUG: motexafin gadolinium|DRUG: temozolomide|PROCEDURE: adjuvant therapy|PROCEDURE: quality-of-life assessment|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Trial of Blood Flow Restriction Plus Physical Therapy vs. Physical Therapy Alone for Lateral Epicondylitis
Status: ACTIVE_NOT_RECRUITING
Conditions: Lateral Epicondylitis
Interventions: DEVICE: Blood flow restriction tourniquet|OTHER: Evidence based physical/occupational therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Single Shot Infraclavicular Brachial Plexus Block vs Local Infiltration After Wrist Arthroscopy Surgery
Status: WITHDRAWN
Conditions: Wrist Injuries|Postoperative Pain Control
Interventions: DRUG: 20ml bolus of 0.5% ropivicaine|DRUG: 10 ml of 0.5% ropivicaine|DRUG: Midazolam|DRUG: Fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ascending Dose Study of CT1812 in Healthy Volunteers
Status: COMPLETED
Conditions: Cognitive Impairment
Interventions: DRUG: CT1812|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Palliative Radiation Therapy in Reducing Pain in Patients With Bone Metastasis
Status: RECRUITING
Conditions: Malignant Neoplasm|Metastatic Malignant Neoplasm in the Bone|Pain
Interventions: RADIATION: External Beam Radiation Therapy|RADIATION: Palliative Radiation Therapy|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Therapeutic HIV Vaccine and Interleukin-2 to Increase the Immune System's Response to HIV
Status: COMPLETED
Conditions: HIV Infections
Interventions: BIOLOGICAL: ALVAC HIV vaccine (vCP1452)|DRUG: Interleukin-2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Application of HBV Rapid Tests as a Tool for Wide-Use Screening
Status: COMPLETED
Conditions: Hepatitis B|Liver Cirrhosis|Carcinoma, Hepatocellular
Interventions: OTHER: ELISA testing|OTHER: Rapid testing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Efficacy and Tolerance Evaluation of a "Revitalizing" Face Treatment
Status: COMPLETED
Conditions: Face Aging/Photo Aging of Moderate Grade
Interventions: OTHER: Nutriage SPF 30 day cream and Nutriage night cream (Difa Cooper S.p.a, Italy)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Timing of Necrosectomy After Endoscopic Drainage of Walled-off Pancreatic Necrosis (WON)
Status: RECRUITING
Conditions: Pancreatic Necrosis
Interventions: PROCEDURE: Endoscopic necrosectomy with step up approach|PROCEDURE: Endoscopic necrosectomy with direct approach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exercise and Diet Intervention in Promoting Weight Loss in Obese Patients With Stage I Endometrial Cancer
Status: WITHDRAWN
Conditions: Estrogen Receptor Positive|Obesity|Progesterone Receptor Positive|Stage I Uterine Corpus Cancer|Stage IA Uterine Corpus Cancer|Stage IB Uterine Corpus Cancer
Interventions: DIETARY_SUPPLEMENT: Dietary Intervention|BEHAVIORAL: Exercise Intervention|OTHER: Laboratory Biomarker Analysis|OTHER: Quality-of-Life Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Combination Chemotherapy Followed by Surgery in Treating Infants With Newly Diagnosed Neuroblastoma.
Status: COMPLETED
Conditions: Neuroblastoma
Interventions: DRUG: carboplatin|DRUG: cyclophosphamide|DRUG: doxorubicin hydrochloride|DRUG: etoposide|DRUG: vincristine sulfate|PROCEDURE: conventional surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Combined Modality Treatment for Resectable Non-Small Cell Superior Sulcus Tumors
Status: COMPLETED
Conditions: Lung Cancer
Interventions: PROCEDURE: Surgery|RADIATION: Chest Irradiation|DRUG: Cisplatin|DRUG: Etoposide|RADIATION: Prophylactic Cranial Irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Oral Administration of 9-cis Rich Powder of the Alga Dunaliella Bardawil on Visual Functions im Patients With Retinitis Pigmentosa
Status: COMPLETED
Conditions: Retinitis Pigmentosa
Interventions: DIETARY_SUPPLEMENT: Alga Dunaliella Bardawil|DIETARY_SUPPLEMENT: Alga Dunaliella Bardawill|OTHER: Sugar pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: the Efficacy of Acarbose and Metformin on Blood Glucose Fluctuation When Combined With Premix Insulin
Status: UNKNOWN
Conditions: Type 2 Diabetes
Interventions: DRUG: premix insulin|DRUG: metformin|DRUG: Acarbose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Study of Implant Surfaces to Enhance Stabilization in Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Partially Edentulous Mandible|Type 2 Diabetes
Interventions: DEVICE: dental implant and modified dental implant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Strategies to Improve Iodine Status in Early Pregnancy
Status: COMPLETED
Conditions: Iodine Deficiency|Pregnancy Related
Interventions: DIETARY_SUPPLEMENT: Cows' milk|OTHER: British Dietetic Association Iodine Fact Sheet.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Extended Safety Study of Montelukast in Infants and Young Children With Chronic Asthma (0476-232)
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: montelukast sodium|DRUG: Comparator: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mesenchymal Stem Cells Transplantation for Ischemic-type Biliary Lesions
Status: UNKNOWN
Conditions: Ischemic-type Biliary Lesions
Interventions: DRUG: huc-MSCs|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Feasibility and Safety of Delivering a Ketone Drink to Comatose Survivors of Out-of-hospital Cardiac Arrest
Status: SUSPENDED
Conditions: Out-Of-Hospital Cardiac Arrest
Interventions: DIETARY_SUPPLEMENT: Ketone ester drink
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Long-term Aspirin Therapy as a Predictor of Decreased Susceptibility to SARS-CoV-2 Infection in Aspirin-Exacerbated Respiratory Disease
Status: RECRUITING
Conditions: AERD - Aspirin Exacerbated Respiratory Disease
Interventions: DRUG: Aspirin 300 Mg Oral Tablet|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effects of 4 Weeks Treatment With Subcutaneous Elamipretide on Left Ventricular Function in Subjects With Stable Heart Failure With Preserved Ejection Fraction
Status: COMPLETED
Conditions: Chronic Heart Failure
Interventions: DRUG: elamipretide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Dose-response Study of Dietary Resveratrol on Lipid Metabolism Disorder
Status: COMPLETED
Conditions: Dyslipidemias
Interventions: DRUG: Mega Resveratrol® capsules|DRUG: Mega Resveratrol® Placebo capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Multicomponent Physical Exercise Program and Mediterranean Diet in Alzheimer's Disease
Status: UNKNOWN
Conditions: Alzheimer Disease|Physical Exercise|Bone Density|Fall
Interventions: OTHER: Multicomponent physical exercise program associated with a Mediterranean diet|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT