pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Cardiovascular Innovation & Research Institute 's NEXUS Registry, the Whole is Greater Than the Parts.
Status: RECRUITING
Conditions: Coronary Artery Disease|Atrial Fibrillation (AF)
Interventions: PROCEDURE: Hybrid procedure|PROCEDURE: Endocardial ablations|PROCEDURE: left atrial appendage occlusion
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Endoscopic Sphincterotomy vs. Balloon Dilation for Assessment of Pancreatitis
Status: UNKNOWN
Conditions: Pancreatitis
Interventions: PROCEDURE: endoscopic sphincterotomy|PROCEDURE: balloon dilatation for 3 minutes|PROCEDURE: balloon dilatation for 6 minutes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Controlled Study on Regulation of Systemic Inflammation by Fecal Bacteria Transplantation in Patients With COVID-19.
Status: COMPLETED
Conditions: Fecal Microbiota Transplantation|COVID-19 Infection
Interventions: PROCEDURE: Fecal microbiota transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Facilitation Through Aggrastat By drOpping or Shortening Infusion Line in Patients With ST-segment Elevation Myocardial Infarction Compared to or on Top of PRasugrel Loading dOse
Status: COMPLETED
Conditions: ST Segment Elevation Myocardial Infarction
Interventions: DRUG: Prasugrel|DRUG: Tirofiban
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Novel Low-Cost Tool for a More Efficient and Reliable Weight-for-Height/Length Assessment
Status: UNKNOWN
Conditions: Severe Acute Malnutrition|Wasting
Interventions: DIAGNOSTIC_TEST: New Method|DIAGNOSTIC_TEST: Existing Method
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparison of Adalimumab and Tofacitinib in the Treatment of Active Takayasu Arteritis
Status: RECRUITING
Conditions: Takayasu Arteritis
Interventions: DRUG: Adalimumab Injection|DRUG: Tofacitinib 5 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Brain Injury and Cognitive Function
Status: RECRUITING
Conditions: Cerebral Lesion|Cognitive Deficit Following Brain Lesions
Interventions: OTHER: imaging|OTHER: Evoked Potentials|OTHER: MEG|BEHAVIORAL: Behavioural tests
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Q10 for Gulf War Veterans
Status: COMPLETED
Conditions: Gulf War Illness
Interventions: DIETARY_SUPPLEMENT: Coenzyme Q10|DIETARY_SUPPLEMENT: Coenzyme Q10|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fluorescence Image Guided Surgery Followed by Intraoperative Photodynamic Therapy for Improving Local Tumor Control in Patients With Locally Advanced or Recurrent Colorectal Cancer
Status: RECRUITING
Conditions: Locally Advanced Colorectal Carcinoma|Recurrent Colorectal Carcinoma|Stage III Colorectal Cancer
Interventions: DRUG: Aminolevulinic Acid|PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|PROCEDURE: Fluorescence-Guided Surgery|PROCEDURE: Magnetic Resonance Imaging|DRUG: Photodynamic Therapy|PROCEDURE: Surgical Procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Determine the Effect of AZD3161,Injected Intradermally, on Quantitative Sensory Testing Variables in Normal and Ultraviolet-C (UVC) Exposed Skin in Healthy Volunteers
Status: COMPLETED
Conditions: Peripheral Neuropathic Pain|Nociceptive Pain
Interventions: DRUG: AZD3161|DRUG: Lidocaine|DRUG: AZD3161 Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Automated Alerts of Patient Deterioration vs. Routine Monitoring of High-risk Patients Admitted to Medical Wards
Status: RECRUITING
Conditions: Alert Fatigue, Health Personnel|Deterioration, Clinical
Interventions: DEVICE: real time alarm of deviating vital signs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Mind-body Treatments for Chronic Back Pain
Status: COMPLETED
Conditions: Chronic Pain|Back Pain Lower Back Chronic|Back Pain, Low
Interventions: OTHER: Open-Label Placebo Treatment for Chronic Back Pain|BEHAVIORAL: Psychotherapy Treatment for Chronic Back Pain
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ridge Preservation Using FDBA and a Collagen Wound Dressing in Molar Sites
Status: COMPLETED
Conditions: Tooth Extraction
Interventions: PROCEDURE: Ridge preservation|DEVICE: FDBA|DEVICE: Collagen wound dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study to Evaluate the Efficacy and Safety of Subcutaneous Amlitelimab in Participants Aged 12 Years and Older With Moderate-to-severe Atopic Dermatitis on Background Topical Corticosteroids
Status: RECRUITING
Conditions: Dermatitis Atopic
Interventions: DRUG: Amlitelimab|DRUG: Placebo|DRUG: Topical corticosteroids|DRUG: Topical calcineurin inhibitors
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Spironolactone and Perioperative Atrial Fibrillation Occurrence in Cardiac Surgery Patients.
Status: UNKNOWN
Conditions: Cardiac Surgery|Atrial Fibrillation|Aldosterone Blockade
Interventions: DRUG: Spironolactone 25mg|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of CyberKnife Stereotactic Radiotherapy in Prostate Cancer
Status: RECRUITING
Conditions: Prostate Cancer
Interventions: RADIATION: Stereotactic Ablative Body Radiotherapy as Monotherapy|RADIATION: Stereotactic Ablative Body Radiotherapy as a Boost
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Probiotics (Lactobacillus Rhamnosus) in Reducing Glucose Intolerance During and After Pregnancy
Status: UNKNOWN
Conditions: Glucose Intolerance|Pregnancy
Interventions: DRUG: Probiotics Lactobacillus Rhamnosus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Visfatin and Omentin-1 - Markers of Nutritional Status of Newborns Born to Diabetic Mothers.
Status: COMPLETED
Conditions: Gestational Diabetes|Diabetes Mellitus|Neonate|Nutritional Status
Interventions: DIAGNOSTIC_TEST: Acquisition and analysis of milk samples|DIAGNOSTIC_TEST: Collection, preparation and analysis of mother's blood samples.|DIAGNOSTIC_TEST: Body composition assessment|OTHER: Anthropometric measurements
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Nivolumab Plus Lenvatinib Against Anaplastic Thyroid Cancer (NAVIGATION)
Status: ACTIVE_NOT_RECRUITING
Conditions: Anaplastic Thyroid Cancer
Interventions: DRUG: Lenvatinib|DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cediranib Versus Placebo Plus Cisplatin/Gemcitabine Chemotherapy for Patients With Advanced Biliary Tract Cancers
Status: COMPLETED
Conditions: Biliary Tract Neoplasms
Interventions: DRUG: gemcitabine|DRUG: cisplatin|DRUG: Placebo|DRUG: cisplatin|DRUG: cediranib|DRUG: gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I Study Comparing Pharmacokinetics and Safety of Bevacizumab
Status: COMPLETED
Conditions: Pharmacokinetics|Safety Issues
Interventions: BIOLOGICAL: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Phase IIB/III Of TG4010 Immunotherapy In Patients With Stage IV Non-Small Cell Lung Cancer
Status: TERMINATED
Conditions: Non-Small-Cell Lung Carcinoma
Interventions: BIOLOGICAL: TG4010|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study of Abraxane Gemcitabine Combination in Patients With Metastatic Breast Cancer
Status: COMPLETED
Conditions: Metastatic Breast Cancer
Interventions: DRUG: Abraxane and Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Intravenous Cardene(Nicardipine)and Labetalol Use in the Emergency Department
Status: COMPLETED
Conditions: Hypertensive Urgency
Interventions: DRUG: nicardipine intravenous|DRUG: Labetalol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Locally Advanced or Metastatic Pancreatic Adenocarcinoma
Status: COMPLETED
Conditions: Pancreatic Adenocarcinoma
Interventions: DRUG: chemotherapy: TS-1, Leucovorin and Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testing the Addition of an Anti-cancer Drug, Abemaciclib, to the Usual Chemotherapy Treatment (Gemcitabine) for Soft Tissue Sarcoma
Status: NOT_YET_RECRUITING
Conditions: Advanced Soft Tissue Sarcoma|Dedifferentiated Liposarcoma|Leiomyosarcoma|Metastatic Soft Tissue Sarcoma|Stage III Soft Tissue Sarcoma of the Trunk and Extremities AJCC v8|Stage IV Soft Tissue Sarcoma of the Trunk and Extremities AJCC v8
Interventions: DRUG: Abemaciclib|PROCEDURE: Biopsy|PROCEDURE: Biospecimen Collection|DRUG: Docetaxel|OTHER: Fluorothymidine F-18|DRUG: Gemcitabine|PROCEDURE: Positron Emission Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vitamin D Deficiency in Adults Following a Major Burn Injury
Status: RECRUITING
Conditions: Vitamin D Deficiency|Burns
Interventions: DRUG: Ergocalciferol Capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Positron Nuclide Labeled NOTA-FAPI PET Study in Lymphoma
Status: UNKNOWN
Conditions: Tumor, Solid|Positron-Emission Tomography|Lymphoma
Interventions: DIAGNOSTIC_TEST: 18F-FDG and 68Ga-NOTA-FAPI04 PET/CT|DIAGNOSTIC_TEST: 18F-FDG and 18F-NOTA-FAPI04 PET/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: DIAGNOSTIC
Clinical trial: Open-Label, Pilot Study of TG100801 in Patients With Choroidal Neovascularization Due to AMD
Status: TERMINATED
Conditions: Macular Degeneration|Choroidal Neovascularization
Interventions: DRUG: TG100801
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Inhaled Cannabinoids Versus Immediate-release Oral Opioids for the Management of Breakthrough Cancer Pain
Status: UNKNOWN
Conditions: Cancer|Breakthrough Cancer Pain
Interventions: DRUG: PPP001|DRUG: Morphine sulfate or Hydromorphone or Oxycodone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Combination Treatment With Peginterferon Alfa-2a (Pegasys) Plus Ribavirin (Copegus) in Participants With Chronic Hepatitis C
Status: COMPLETED
Conditions: Hepatitis C, Chronic
Interventions: DRUG: Peginterferon alfa-2a|DRUG: Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Adverse Events and Change in Disease Activity of Subcutaneous (SC) Epcoritamab As Monotherapy or Combined With Standard of Care Therapies in Adult Participants in China With B-Cell Non-Hodgkin Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: B-Cell Non-Hodgkin Lymphoma
Interventions: DRUG: Epcoritamab|DRUG: Cyclophosphamide|DRUG: Rituximab|DRUG: Doxorubicin|DRUG: Vincristine|DRUG: Prednisone|DRUG: Lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety and Pharmacokinetic Study of Paliperidone Palmitate in Patients With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Paliperidone palmitate Treatment A|DRUG: Paliperidone palmitate Treatment B
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antihypertensive Effect of Simvastatin in Hypertensive Patients
Status: UNKNOWN
Conditions: Hypertension
Interventions: DRUG: Simvastatin 40mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Vaccine Therapy in Treating Patients With Colorectal Cancer Metastatic to the Liver
Status: COMPLETED
Conditions: Colorectal Cancer|Metastatic Cancer
Interventions: BIOLOGICAL: monoclonal antibody 11D10 anti-idiotype|BIOLOGICAL: monoclonal antibody 3H1 Alu Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Use of Coconut Oil for the Prevention and Treatment of Diaper Dermatitis in the NICU Population
Status: UNKNOWN
Conditions: Dermatitis, Contact
Interventions: OTHER: Organic, Unrefined Coconut Oil|OTHER: Medline Remedy Phytoplex Z-Guard Skin Protectant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Absorption, Elimination and Safety of 14C-labeled Radioactive BTZ-043, a New Compound in TB Treatment
Status: COMPLETED
Conditions: Tuberculosis|Tuberculosis, Pulmonary|Bacterial Infections Respiratory|Lung Diseases|Mycobacterium Infections
Interventions: DRUG: 500mg BTZ-043 containing 3.7 MBq of [14C]BTZ-043
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of 18-F Sodium Fluoride Uptake in Culprit Plaques Between Acute Coronary Syndrome and Stable Angina
Status: TERMINATED
Conditions: Coronary Artery Diseases
Interventions: OTHER: 18-F Sodium Fluoride Uptake in Positron emission tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effects of InFat™ Product on Stool Biochemistry and Stool Characteristics in Formula-fed Term Chinese Infants
Status: TERMINATED
Conditions: Healthy
Interventions: BEHAVIORAL: Infant formula feeding (InFat™)|DIETARY_SUPPLEMENT: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Evaluate the Safety and Efficacy of an Investigational Drug in HIV Infected Patients (0518-004)(COMPLETED)
Status: COMPLETED
Conditions: HIV Infections|Acquired Immunodeficiency Syndrome
Interventions: DRUG: Comparator: MK0518 monotherapy|DRUG: Comparator: MK0518 combination therapy|DRUG: Comparator: efavirenz|DRUG: Comparator: tenofovir|DRUG: Comparator: lamivudine|DRUG: Placebo monotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Cytokine-induced Killer (CIK) Cells as Therapy or Adjuvant Treatment for Advanced HCC
Status: UNKNOWN
Conditions: Liver Cancer
Interventions: BIOLOGICAL: CIK|PROCEDURE: TACE
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Maraviroc Plus Darunavir/Ritonavir for Treatment-Naïve Patients Infected With R5-tropic HIV-1
Status: COMPLETED
Conditions: HIV-1 Infection|HIV Infections
Interventions: DRUG: maraviroc|DRUG: darunavir|DRUG: ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Retroperitoneal Lymph Node Dissection in Treating Patients With Testicular Seminoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Lymphadenopathy|Stage I Testicular Seminoma|Stage II Testicular Seminoma
Interventions: OTHER: Laboratory Biomarker Analysis|PROCEDURE: Retroperitoneal Lymph Node Dissection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Increasing Levothyroxine Dose in Ramadan for UAE Patients With Hypothyroidism
Status: COMPLETED
Conditions: L-thyroxine
Interventions: DRUG: Extra dose of L-thyroxine, 25 mcg during Ramadan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Effect of Multiple Doses of BIRT 2584 XX Tablets on the Pharmacokinetic Parameters of Midazolam in Healthy Male Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BIRT 2584 XX|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Evaluate the Efficacy/Safety of Osimertinib Prior to CRT and Maintenance of it With Stage III, Unresectable NSCLC With EGFR Mutations
Status: RECRUITING
Conditions: Lung Cancer
Interventions: DRUG: Osimertinib|DRUG: Cisplatin or Carboplatin; Pemetrexed or Paclitaxel|DRUG: Radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Mortality Reduction of Enoxaparin in Hospitalized Acutely Ill Medical Receiving Enoxaparin
Status: COMPLETED
Conditions: Acute Illness
Interventions: DRUG: Enoxaparin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Effectiveness of a Cognitive Behavioral Intervention (CBI)
Status: RECRUITING
Conditions: Adolescent Behavior|Dental Plaque|Gingivitis|Cognitive Change
Interventions: BEHAVIORAL: Cognitive behavioral intervention|OTHER: Colgate smart toothbrush
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Brain Function Evaluation and Intervention System for Acute and Prolonged Disorders of Consciousness
Status: ENROLLING_BY_INVITATION
Conditions: Disorder of Consciousness
Interventions: DEVICE: Transcranial magnetic stimulation|DEVICE: Sham Transcranial magnetic stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Lymph Drainage on Patients With Axillary Web Syndrome
Status: NOT_YET_RECRUITING
Conditions: Movement Disorders
Interventions: OTHER: Physical therapy program|OTHER: Physical therapy program with lymphedema drainage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: The Impact of Liraglutide on Glucose Tolerance and the Risk of Type 2 Diabetes in Women With Previous Pregnancy-induced Diabetes
Status: COMPLETED
Conditions: Gestational Diabetes Mellitus
Interventions: DRUG: Liraglutide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Study to Evaluate Combined Treatment of Daratumumab, Bortezomib and Dexamethasone in PBL Patients.
Status: RECRUITING
Conditions: Plasmablastic Lymphoma
Interventions: DRUG: Daratumumab|DRUG: Bortezomib|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Role of Branched-chain Amino Acids Infusion as Adjunct Therapy Post Liver Surgery for Patients in Intensive Care Unit
Status: COMPLETED
Conditions: Liver Function Post BCAA Infusion
Interventions: DRUG: BCAA preparation Intravenous infusion|DRUG: sterile normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Stepped Enhancement of PTSD Services Using Primary Care (STEPS UP): A Randomized Effectiveness Trial
Status: COMPLETED
Conditions: Posttraumatic Stress Disorder (PTSD)|Depression
Interventions: BEHAVIORAL: STEPS UP|BEHAVIORAL: OUC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized, Placebo-Controlled Study of an Herbal Tea to Support Lactation
Status: COMPLETED
Conditions: Lactation
Interventions: DIETARY_SUPPLEMENT: study herbal tea|DIETARY_SUPPLEMENT: herbal placebo tea
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Safety and Efficacy Study of Panzem® Nanocrystal Colloidal Dispersion in Patients With Ovarian Cancer
Status: COMPLETED
Conditions: Ovarian Cancer
Interventions: DRUG: Panzem Nanocrystal Colloidal Dispersion (NCD)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Development of Intravitreal Ranibizumab by Determining the Pathogenesis of Macular Edema With Retinal Vein Occlusion
Status: UNKNOWN
Conditions: Macular Edema|Branch Retinal Vein Occlusion|Central Retinal Vein Occlusion
Interventions: DRUG: ranibizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of Therapy With Hylan G-F 20 Exercise Capacity
Status: TERMINATED
Conditions: Knee Osteoarthritis
Interventions: DEVICE: Hylan G-F 20|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of Certolizumab Pegol to Evaluate Pharmacokinetics and Safety in Adult Healthy Chinese Subjects
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: BIOLOGICAL: Certolizumab Pegol|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: DSUVIA Early Evaluation of Pain Trial
Status: COMPLETED
Conditions: Traumatic Injury
Interventions: DRUG: Sufentanil 30 MCG Sublingual Tablet|DRUG: standard care pain treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cisplatin Plus Raltitrexed or 5-fluorouracil Concurrent With Radiotherapy for Head and Neck Squamous Cell Cancer
Status: UNKNOWN
Conditions: Head and Neck Squamous Cell Cancer
Interventions: DRUG: Raltitrexed|DRUG: 5-fluorouracil|DRUG: Cisplatin|RADIATION: IMRT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Examining PrEP-001 in Healthy Subjects
Status: COMPLETED
Conditions: Influenza A H3N2
Interventions: DRUG: PrEP-001|OTHER: Placebo Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Randomized Phase III Study of Intensive Chemotherapy With or Without Dasatinib (Sprycel™)
Status: COMPLETED
Conditions: Acute Myeloid Leukemia (AML)
Interventions: DRUG: Dasatinib|DRUG: Cytarabine|DRUG: Daunorubicin|DRUG: Idarubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ph1 Volasertib Plus Romidepsin in R/R PTCL and CTCL
Status: WITHDRAWN
Conditions: PTCL|CTCL
Interventions: DRUG: Volasertib|DRUG: Romidepsin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Intranasal Oxytocin in Patients With Central Diabetes Insipidus
Status: NOT_YET_RECRUITING
Conditions: Central Diabetes Insipidus
Interventions: DRUG: Oxytocin nasal spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparative Usability Evaluation of Sustained Acoustic Medicine (SAM) Devices and Topical Gel for OA Knee Pain
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: DEVICE: Sustained Acoustic Device with 2.5% Diclofenac Patch|DRUG: 1% Diclofenac Topical Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: IL-7 and IL-7R Expression in RA Patients With Active vs. Inactive Disease Treated With DMARD or CIMZIA
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: OTHER: Lab Work|DRUG: Certolizumab pegol (CDP870, tradename Cimzia)(prefilled syringes at the dose of 200mg)|DRUG: Certolizumab pegol (CDP870, tradename Cimzia)|DRUG: Hydroxychloroquine|DRUG: Sulfasalazine|DRUG: Medrol|DRUG: Prednisone|DRUG: Triamcinolone|DRUG: Naproxen|DRUG: Leflunomide|DRUG: Methotrexate|DRUG: humira
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Vildagliptin vs. Glibenclamide on Circulating Endothelial Progenitor Cell Number Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: Vildagliptin|DRUG: Glibenclamide|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Effects of Cabotegravir (CAB) and Rilpivirine (RPV) Long-Acting (LA) Injections Following Sub-cutaneous (SC) Administration Compared With Intramuscular (IM) Administration in Adult Participants Living With Human Immunodeficiency Virus (HIV-1) Infection in the FLAIR Study
Status: COMPLETED
Conditions: Human Immunodeficiency Virus Type 1 (HIV-1)
Interventions: DRUG: Cabotegravir - Injectable Suspension (CAB LA)|DRUG: Rilpivirine - Injectable Suspension (RPV LA)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transcutaneous Electrical Acupoint Stimulation to Improve Pregnancy Rates for Women Undergoing in Vitro Fertilization
Status: UNKNOWN
Conditions: Supervision of Pregnancy Resulting From In-vitro Fertilization
Interventions: DEVICE: transcutaneous electrical acupoint stimulation (TEAS);EA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Umbrella Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Patients With Gastric or Gastroesophageal Junction Carcinoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Gastric and Gastroesophageal Junction Carcinoma
Interventions: DRUG: Atezolizumab|DRUG: Capecitabine|DRUG: Oxaliplatin|DRUG: Tiragolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Evaluation of a Multi-target Stool DNA (Mt-sDNA) Test, Cologuard, for CRC Screening in Individuals Aged 45-49 and at Average Risk for Development of Colorectal Cancer: Act Now
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DIAGNOSTIC_TEST: mt-sDNA screening test|PROCEDURE: Colonoscopy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Trial of Micronutrients and Adverse Pregnancy Outcomes
Status: COMPLETED
Conditions: Pregnancy|Premature Birth|Infant, Low Birth Weight|Pregnancy Outcomes
Interventions: DIETARY_SUPPLEMENT: Multivitamins-vitamins B-complex, C, and E|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study to Evaluate Postoperative Analgesia in Subjects Undergoing Hemorrhoidectomy
Status: COMPLETED
Conditions: Hemorrhoids
Interventions: DRUG: Bupivacaine HCl|DRUG: SKY0402
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study With Atezolizumab in Combination With Trastuzumab and Vinorelbine in HER2-positive Advanced/Metastatic Breast Cancer
Status: RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Atezolizumab + Trastuzumab + Vinorelbine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aloe Vera in Irritable Bowel Syndrome
Status: COMPLETED
Conditions: Irritable Bowel Syndrome
Interventions: DIETARY_SUPPLEMENT: Aloe vera effervescent tablet (AVH200)|DIETARY_SUPPLEMENT: Placebo control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Aquanet Bowel Cleansing Device Versus Oral Sodium Picosulfate for Pre-endoscopy Bowel Preparation
Status: COMPLETED
Conditions: Bowel Preparation
Interventions: DEVICE: Aquanet|DRUG: Sodium Picosulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I Trial of AZD1775 and Belinostat in Treating Patients With Relapsed or Refractory Myeloid Malignancies or Untreated Acute Myeloid Leukemia
Status: TERMINATED
Conditions: Acute Myeloid Leukemia|Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive|Myelodysplastic Syndrome|Previously Treated Myelodysplastic Syndrome|Recurrent Adult Acute Myeloid Leukemia|Recurrent Chronic Myelogenous Leukemia, BCR-ABL1 Positive|Refractory Acute Myeloid Leukemia|Refractory Chronic Myelogenous Leukemia, BCR-ABL1 Positive|Secondary Acute Myeloid Leukemia|Therapy-Related Acute Myeloid Leukemia|Untreated Adult Acute Myeloid Leukemia
Interventions: DRUG: Adavosertib|DRUG: Belinostat|OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacological Study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MEDIHONEY® Gel Versus Collagenase for Wound Debridement
Status: TERMINATED
Conditions: Ulcer|Wounds
Interventions: DEVICE: Active Leptospermum Honey (Medihoney)|DRUG: Collagenase
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: COmbinAtion Therapy of dieT With biologicalS for Crohn's Disease: the OATS Study
Status: RECRUITING
Conditions: Crohn Disease|Inflammatory Bowel Diseases|Diet, Healthy
Interventions: OTHER: FIT diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Emotion and Craving Regulation Among Individuals With Internet Gaming Disorders
Status: COMPLETED
Conditions: Internet Gaming Disorder|Emotion Regulation
Interventions: PROCEDURE: Emotion Regulation Task|PROCEDURE: Craving Regulation Task
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of a Surgical Microscope Mounted Autorefractor When Used on Patients Lying in a Supine Position
Status: COMPLETED
Conditions: Refractive Error
Interventions: DEVICE: Intraoperative Autorefractor IAR-1|DEVICE: Hartmann-Shack Auto Refractor
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Palliative Care Intervention in Improving Symptom Control and Quality of Life in Patients With Stage II-IV Non-small Cell Lung Cancer and Their Family Caregivers
Status: COMPLETED
Conditions: Caregiver|Psychological Impact of Cancer and Its Treatment|Recurrent Non-small Cell Lung Cancer|Stage IIA Non-small Cell Lung Cancer|Stage IIB Non-small Cell Lung Cancer|Stage IIIA Non-small Cell Lung Cancer|Stage IIIB Non-small Cell Lung Cancer|Stage IV Non-small Cell Lung Cancer
Interventions: OTHER: Palliative Therapy|OTHER: quality-of-life assessment|OTHER: questionnaire administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Determine the Number of Patients Who Reach Optimal Cholesterol Levels on Each of Three Different Treatments (0653A-121)
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DRUG: ezetimibe (+) simvastatin|DRUG: Comparator: atorvastatin|DRUG: Comparator: rosuvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: the Laparoscopic and Endoscopic Cooperative Surgery of Gastrointestinal Stromal Tumor
Status: UNKNOWN
Conditions: Gastrointestinal Stromal Tumor
Interventions: PROCEDURE: Laparoscopic endoscopy combined surgery|PROCEDURE: laparoscopic and endoscopic cooperative surgery|PROCEDURE: Single-arch laparoscopic and endoscopic cooperative surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: TRK-700 Drug-Drug Interaction Study With Digoxin and Midazolam
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: TRK-700|DRUG: Digoxin|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Everolimus (RAD001) as Therapy for Patients With Systemic Mastocytosis
Status: COMPLETED
Conditions: Systemic Mastocytosis
Interventions: DRUG: RAD001 (Everolimus)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Registry of Multicenter Brain-Heart Comorbidity in China
Status: RECRUITING
Conditions: Ischemic Heart Disease|Cardiac Arrest|Atrial Fibrillation|Heart Failure|Aortic Diseases|Subarachnoid Hemorrhage|Intracerebral Hemorrhage|Cerebral Infarction|Occlusion and Stenosis of Precerebral Arteries|Occlusion and Stenosis of Cerebellar Arteries|Cerebral Aneurysm|Moyamoya Disease|Arteriovenous Malformation of Cerebral Vessels
Interventions: OTHER: Multi-disciplinary assessment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Impact of Anti-Tumor Necrosis Factor (TNF) Antibodies on the T-lymphocyte and Macrophage Cooperation in Crohn Disease
Status: TERMINATED
Conditions: Crohn Disease
Interventions: PROCEDURE: rectosigmoïdal biopsies
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Calcium Chloride on Recovery From Neuromuscular Blockade
Status: COMPLETED
Conditions: Residual Neuromuscular Blockade
Interventions: DRUG: Calcium|DRUG: control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Assessment of Foralumab Safety and Modulation of Microglial Activation
Status: NOT_YET_RECRUITING
Conditions: Dementia|Alzheimers Disease|Mild Cognitive Impairment Due to Alzheimer's Disease
Interventions: DRUG: Foralumab TZLS-401 50 µg|DRUG: Foralumab TZLS-401 100 µg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Bicarbonate in Patients With Out-of-hospital Cardiac Arrest
Status: COMPLETED
Conditions: Cardiac Arrest|Metabolic Acidosis
Interventions: DRUG: Sodium bicarbonate|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: StrataXRT vs. Standard Clinical Practice in the Prevention and Treatment of Radiation Dermatitis
Status: COMPLETED
Conditions: Radiation Dermatitis
Interventions: DEVICE: StrataXRT|OTHER: Sorbolene
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination of Cisplatin, Docetaxel and Bevacizumab in Patients With Non-small Cell Lung Carcinoma (NSCLC)
Status: COMPLETED
Conditions: NSCLC
Interventions: DRUG: Bevacizumab|DRUG: Cisplatin|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transvaginal NOSES Versus Conventional Laparoscopic Surgery for Right Hemicolectomy
Status: RECRUITING
Conditions: Colon Cancer
Interventions: PROCEDURE: NOSES VIIIA|PROCEDURE: laparoscopic surgery with mini-laparotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exergaming Versus Aerobic Exercises on Mild Cognitive Impairment
Status: COMPLETED
Conditions: Type 2 Diabetes|Cognitive Impairment
Interventions: OTHER: Exergaming Training Group|OTHER: Aerobic Exercise Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Non-Invasive Shunt Quantification in Interatrial Communication
Status: TERMINATED
Conditions: Congenital Heart Diseases|Hemodynamic|Cardiac Output
Interventions: DEVICE: Innocor®|DEVICE: Physioflow®
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study of Steady-state Carbamazepine on the Single-dose of Erdafitinib Tablets in Healthy Adult Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Erdafitinib|DRUG: Carbamazepine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Sorafenib and Dacarbazine in Soft Tissue Sarcoma
Status: COMPLETED
Conditions: Sarcoma|Synovial Sarcoma|Leiomyosarcoma|Malignant Peripheral Nerve Sheath Tumor
Interventions: DRUG: Sorafenib and Dacarbazine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Subconjunctival Injection of Triamcinolone Acetonide and Limited Peritomy During Pterygium Excision
Status: COMPLETED
Conditions: Pterygium
Interventions: PROCEDURE: intraoperative subconjunctival injection of triamcinolone acetonide and limited peritomy during bare scleral pterygium excision
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy, Safety, and Tolerability of NDI-034858 in Participants With Active Psoriatic Arthritis
Status: COMPLETED
Conditions: Psoriatic Arthritis
Interventions: DRUG: NDI-034858|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: "Cocktail" Therapy for Hepatitis B Related Hepatocellular Carcinoma
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Cyclophosphamide|BIOLOGICAL: Multiple Signals loaded Dendritic Cells Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Preoperative Low-residue Diet on Postoperative Ileus Following Cesarean Section
Status: COMPLETED
Conditions: Cesarean Section Complications
Interventions: DIETARY_SUPPLEMENT: Low-residue diet|DIETARY_SUPPLEMENT: Free diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Does Tension-Free Herniorrhaphy or Laparoscopic Herniorrhaphy Achieve Equal or Better Recurrence Rates and Lower Costs While Achieving Equivalent Outcomes for Hernia Patients?
Status: COMPLETED
Conditions: Hernia
Interventions: PROCEDURE: Standardized tension-free herniorrhaphy with prosthesis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Analysis of Current Situation and Evaluation of Trauma Treatment Training in China
Status: COMPLETED
Conditions: Train Accident Involving Explosion, Passenger Injured|Train Collision With Streetcar, Pedestrian Injured|Trauma Injury|Train Accident Involving Burning, Passenger Injured
Interventions: BEHAVIORAL: standard trauma care taining
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study of the Safety and Pharmacokinetics of BGB-283 (Lifirafenib) and PD-0325901 (Mirdametinib) in Participants With Advanced or Refractory Solid Tumors
Status: RECRUITING
Conditions: Solid Tumor, Adult
Interventions: DRUG: Lifirafenib|DRUG: mirdametinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Guanfacine Extended-release for Adolescents With Cannabis Use
Status: RECRUITING
Conditions: Cannabis Use Disorder
Interventions: DRUG: Guanfacine Extended Release Oral Tablet|BEHAVIORAL: Residential withdrawal|BEHAVIORAL: Engagement with alcohol and other drug services|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Substitution Between Different Tobacco/Nicotine Products as a Function of Tobacco-user Type
Status: ACTIVE_NOT_RECRUITING
Conditions: Cigarette Smoking|Nicotine Vaping
Interventions: OTHER: All nicotine/ tobacco products at market price|OTHER: Nicotine vaping products at 1/2 market price|OTHER: Nicotine vaping products at 2x market price|OTHER: Heated tobacco products at 1/2 market price.|OTHER: Heated tobacco products at 2x market price.|OTHER: Nicotine pouch products at 1/2 market price.|OTHER: Nicotine pouch products at 2x market price.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Regorafenib and XmAb20717 in Treatment of High-risk Patients With Colorectal Cancer With Radiographic Occult Molecular Residual Disease After End of Established Definitive Therapy (RX-CROME)
Status: WITHDRAWN
Conditions: Colorectal Cancer|Colon Cancer|Rectum Cancer
Interventions: DRUG: Regorafenib|DRUG: XmAb20717
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Pharmacokinetics of Subcutaneous Injection of OCTA101 in Adult Patients With Severe Hemophilia A
Status: TERMINATED
Conditions: Severe Hemophilia A
Interventions: DRUG: OCTA101
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Outpatient Study Of The Efficacy, Safety, And Tolerability Of PF-02545920 In The Adjunctive Treatment Of Sub-Optimally Controlled Symptoms of Schizophrenia
Status: TERMINATED
Conditions: Schizophrenia
Interventions: DRUG: PF-02545920|DRUG: Placebo|DRUG: PF-02545920
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Robotic Interventions for Spasticity Treatment
Status: SUSPENDED
Conditions: Stroke|Spasticity, Muscle
Interventions: DEVICE: Conventional robotic continuous passive movement training|DEVICE: Visual Feedback|DEVICE: Haptic and Visual Feedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of Zinc Oxide Eugenol to Ferric Sulphate Pulpotomy in Primary Teeth
Status: COMPLETED
Conditions: Pulpotomy
Interventions: PROCEDURE: Pulp hemostasis with a dry cotton pellet|PROCEDURE: Pulp hemostasis with a wet cotton pellet impregnated with FS|PROCEDURE: Stainless steel crown
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Carmustine Plus O(6)-Benzylguanine in Treating Patients With Recurrent or Progressive Gliomas of the Brain
Status: COMPLETED
Conditions: Brain and Central Nervous System Tumors
Interventions: DRUG: O6-benzylguanine|DRUG: carmustine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT