pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Phase Ⅱ Study of Hemay808 for Atopic Dermatitis Patients
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: Hemay808
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tirapazamine, Cisplatin, and Radiation Therapy in Treating Patients With Stage IB, Stage II, Stage III, or Stage IVA Cervical Cancer
Status: COMPLETED
Conditions: Cervical Cancer
Interventions: DRUG: cisplatin|DRUG: tirapazamine|RADIATION: brachytherapy|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Comparative Effects of Buteyko Exercise and Corpse-Pose Technique on Cardiac Surgery Patients
Status: COMPLETED
Conditions: Post-Cardiac Surgery Patients
Interventions: OTHER: Buteyko Breathing Technique|OTHER: Corpse-Pose Technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of CKD-828 to Stage 2 Hypertension
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: CKD-828 2.5/40mg|DRUG: CKD-828 5/40mg|DRUG: CKD-828 5/80mg|DRUG: S-amlodipine 2.5mg|DRUG: S-amlodipine 5mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison Between C3-6 Laminoplasty and C3 Laminectomy With Cervical Laminoplasty
Status: COMPLETED
Conditions: Myelopathy Cervical|Kyphosis Post Surgical|Neck Pain|Ossification of Posterior Longitudinal Ligament|Cervical Spondylosis With Myelopathy
Interventions: PROCEDURE: C3 laminectomy|PROCEDURE: C3 laminoplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Oshadi D and Oshadi R for Malignant Mesothelioma Treatment
Status: SUSPENDED
Conditions: Mesothelioma
Interventions: DRUG: Oshadi D and Oshadi R
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cardiac Rehabilitation in Patients With Continuous Flow Left Ventricular Assist Devices:Rehab VAD Trial
Status: COMPLETED
Conditions: Heart Failure
Interventions: BEHAVIORAL: Cardiac Rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: PSMA-Directed Para-Aortic Radiation Therapy for Oligorecurrent Prostate Cancer
Status: RECRUITING
Conditions: Prostate Cancer|Prostate Adenocarcinoma|Hormone Sensitive Prostate Cancer
Interventions: RADIATION: Para Aortic Radiation Therapy: Photon Therapy|RADIATION: Para Aortic Radiation Therapy: Proton Therapy|DRUG: Androgen Deprivation Therapy|DRUG: Androgen Receptor Signaling Inhibitor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Combined Aerobic Exercise and Cognitive Training (ACT) Trial: The ACT Trial
Status: COMPLETED
Conditions: Mild Cognitive Impairment
Interventions: BEHAVIORAL: Aerobic & Cognitive Training (ACT)|BEHAVIORAL: Cycling Only|BEHAVIORAL: Cognitive Training Only|BEHAVIORAL: Stretching and Mental Stimulating Activities
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of the Release of the Intrathoracic Fascia on Thoracic Rotation Mobility
Status: COMPLETED
Conditions: Fascia; Inflammation|Thoracic|Rotation
Interventions: OTHER: Measuring thoracic rotation mobility
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Black Education and Treatment of Hypertension (BEAT HTN)
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Hydrochlorothiazide|DRUG: Lisinopril|DRUG: Lisinopril and Hydrochlorothiazide|DRUG: Nifedipine XL|DRUG: Metoprolol tartrate|DRUG: Atenolol|DRUG: Valsartan|DRUG: Doxazosin|DRUG: Clonidine|DRUG: Hydralazine|DRUG: Metoprolol succinate|DRUG: Amlodipine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pinometostat and Azacitidine in Treating Patients With Relapsed, Refractory, or Newly Diagnosed Acute Myeloid Leukemia With 11q23 Rearrangement
Status: COMPLETED
Conditions: Acute Myeloid Leukemia With t(9;11)(p21.3;q23.3); MLLT3-MLL|Leukemia Cutis|Recurrent Acute Myeloid Leukemia|Refractory Acute Myeloid Leukemia
Interventions: DRUG: Azacitidine|DRUG: Pinometostat
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of a School-based Exercise Program on Posture, Trunk Range of Motion, and Musculoskeletal Pain
Status: COMPLETED
Conditions: Musculoskeletal and Connective Tissue Disorders
Interventions: OTHER: School-based exercise program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Recovering From COVID-19 Lingering Symptoms Adaptive Integrative Medicine Trial - Effect of Hyperbaric Oxygen Therapy for the Treatment of Post COVID Condition
Status: NOT_YET_RECRUITING
Conditions: Long COVID|Post COVID Condition|Post Acute Sequelae of COVID-19
Interventions: DEVICE: Hyperbaric Oxygen therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vitamin B12 Dose Escalation Trial in Pregnancy
Status: ACTIVE_NOT_RECRUITING
Conditions: Vitamin B 12 Deficiency
Interventions: DRUG: Vitamin B12 2.6 µg|DRUG: Vitamin B12 10 µg|DRUG: Vitamin B12 50 µg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Assess the Safety and Efficacy of Risankizumab for Maintenance in Moderate to Severe Plaque Type Psoriasis ( LIMMITLESS )
Status: COMPLETED
Conditions: Psoriasis
Interventions: BIOLOGICAL: risankizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Cooling Sensation of an Allergy Product in Adults With a History of Allergies
Status: COMPLETED
Conditions: Allergic Rhinitis
Interventions: DRUG: Loratadine (Claritin, BAY76-2211)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Weaning Preterm Neonates From Nasal Continuous Positive Airway Pressure
Status: COMPLETED
Conditions: Respiratory Distress Syndrome|Hyaline Membrane Disease|Preterm Infants|Premature Infants
Interventions: DEVICE: CPAP|DEVICE: Nasal Cannula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ColonCancerCheck Mailed Invitations: An Evaluation
Status: COMPLETED
Conditions: Colorectal Disorders
Interventions: OTHER: Males control group: Deferred letter|OTHER: Males Group 1: Current CCC invitation letter|OTHER: Males Group 2: New letter with neutral gender content|OTHER: Males Group 3: New letter with male-specific content|OTHER: Females control group: Deferred letter|OTHER: Females Group 1: Current CCC invitation letter|OTHER: Females Group 2: New letter with neutral gender content
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SCREENING
Clinical trial: Single Dose Study of MK-2060 to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics in Older Japanese Participants on Dialysis (MK-2060-012)
Status: COMPLETED
Conditions: End-Stage Renal Disease (ESRD)|End-Stage Kidney Disease (ESKD)|Kidney Failure, Chronic
Interventions: BIOLOGICAL: MK-2060|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Super-Selective Intraarterial Infusion of Cetuximab (Erbitux) With or Without Radiation Therapy for the Treatment of Unresectable Recurrent Squamous Cell Carcinoma of the Head and Neck
Status: TERMINATED
Conditions: Carcinoma, Squamous Cell|Carcinoma, Squamous Cell of Head and Neck
Interventions: DRUG: Intraarterial Cetxuimab (Erbitux)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Drug-drug Interaction Between Belumosudil, Itraconazole, Rifampicin, Rabeprazole, and Omeprazole in Healthy Volunteers
Status: COMPLETED
Conditions: Drug-drug Interaction|Autoimmune Diseases|Fibrotic Disease
Interventions: DRUG: Belumosudil|DRUG: Itraconazole|DRUG: Rabeprazole|DRUG: Rifampicin|DRUG: Omeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Electrophysiological and Clinical Effects of Walking Downhill in Stroke Patients
Status: NOT_YET_RECRUITING
Conditions: Stroke
Interventions: PROCEDURE: Downhill walking|PROCEDURE: Walking on flat ground
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: TTI-0102 for Veterans With TBI
Status: WITHDRAWN
Conditions: Mild to Moderate TBI|Posttraumatic Stress Disorder
Interventions: DRUG: TTI-0102|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lorazepam Sedation for Critically Ill Children
Status: COMPLETED
Conditions: Critical Illness
Interventions: DRUG: Lorazepam|DRUG: Midazolam|DRUG: Lorazepam CI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial to Investigate the Relative Efficacy, Safety, and Tolerability of Octaplas LG Versus Octaplas SD
Status: COMPLETED
Conditions: Comparison of Octaplas LG and Octaplas SD
Interventions: BIOLOGICAL: Octaplas LG|BIOLOGICAL: Octaplas SD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Different Anti-Spastic Therapy Strategies After CABG Using Radial Artery Grafts
Status: COMPLETED
Conditions: Coronary Artery Bypass Graft|Radial Artery Grafts|Antispastic Therapy|Pilot Study
Interventions: DRUG: Nicorandil 5mg tid|DRUG: Diltiazem 180mg qd|DRUG: Isosorbide Mononitrate 50mg qd
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Device Performance of the Uriprene® Degradable Temporary Ureteral Stent Following Uncomplicated Ureteroscopy
Status: RECRUITING
Conditions: Ureteral Diseases
Interventions: DEVICE: Uriprene® Degradable Temporary Ureteral Stent
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility Study - Neofact
Status: COMPLETED
Conditions: Respiratory Distress Syndrome in Premature Infant|Surfactant Deficiency Syndrome Neonatal
Interventions: DEVICE: Neofact application aid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: FusionVAC22_01: Fusion Transcript-based Peptide Vaccine Combined With Immune Checkpoint Inhibition
Status: RECRUITING
Conditions: Fibrolamellar Hepatocellular Carcinoma
Interventions: DRUG: Fusion-VAC-XS15
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Autologous SCT Followed by Dendritic Cell p53 Vaccination in Patients With Limited Stage Small Cell Lung Cancer
Status: TERMINATED
Conditions: Small Cell Lung Cancer
Interventions: BIOLOGICAL: Combined adenovirus vectored p53 tranfected dedritic cell vaccine and ex vivo expanded T-lymphocytes
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combidex USPIO - Ultra-small Superparamagnetic Iron Oxide
Status: COMPLETED
Conditions: Uterine Neoplasms|Cervix Neoplasms|Bladder Neoplasms|Prostatic Neoplasms
Interventions: PROCEDURE: MRI contrast agent Combidex (ferumoxtran-10)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy of Cardioviva™ Probiotic Yogurt Formulation
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DIETARY_SUPPLEMENT: Cardioviva™ yogurt|DIETARY_SUPPLEMENT: Placebo yogurt
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of Two Electric Breast Pumps in Mothers of Term Infants.
Status: UNKNOWN
Conditions: Volume of Breast Milk Expressed Using Single Electric Breast Pumps.|Duration of Exclusive Breast-feeding|Duration of Any Breast-feeding
Interventions: DEVICE: Electric breast pump - A|DEVICE: Electric breast pump - B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Preliminary Evaluation of Uptake of [68Ga]P16-093 in Metastatic Prostate and Renal Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Cancer|Renal Cancer
Interventions: DRUG: [68Ga]P16-093
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Switch to Tenofovir Versus Continue Lamivudine/Adefovir Treatment in Lamivudine-resistance Chronic Hepatitis B Patients
Status: UNKNOWN
Conditions: Chronic Hepatitis B
Interventions: DRUG: Tenofovir disoproxil fumarate|DRUG: Lamivudine plus adefovir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Biomarker (p53 Gene) Analysis and Combination Chemotherapy Followed by Radiation Therapy and Surgery in Treating Women With Large Operable or Locally Advanced or Inflammatory Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: BIOLOGICAL: filgrastim|DRUG: cyclophosphamide|DRUG: docetaxel|DRUG: epirubicin hydrochloride|DRUG: fluorouracil|GENETIC: microarray analysis|OTHER: immunohistochemistry staining method|OTHER: laboratory biomarker analysis|PROCEDURE: biopsy|PROCEDURE: conventional surgery|PROCEDURE: neoadjuvant therapy|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Sotorasib (AMG 510) in Participants With Stage IV NSCLC Whose Tumors Harbor a KRAS p.G12C Mutation in Need of First-line Treatment
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: Sotorasib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mechanism of Class II Correction With Fixed Lingual Mandibular Growth Modificator (FLMGM)
Status: COMPLETED
Conditions: Class II Division 1 Malocclusion
Interventions: DEVICE: Fixed Lingual Mandibular Growth Modificator (FLMGM)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improving Secretion of Insulin in New Onset Diabetes After Renal Transplantation
Status: TERMINATED
Conditions: New Onset Diabetes Mellitus After Renal Transplantation
Interventions: DRUG: Cyclosporine A|DRUG: Tacrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: LIBRE (Ligamys, Internal Bracing, REconstruction) Study: Comparing Three Surgery Techniques After an Acute ACL Rupture.
Status: ACTIVE_NOT_RECRUITING
Conditions: Anterior Cruciate Ligament Rupture
Interventions: PROCEDURE: Dynamic Intraligamentary Stabilization|PROCEDURE: Internal Brace Ligament Augmentation|PROCEDURE: ACL Reconstruction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Clinical and Radiographic Evaluation of Pulpotomies in Primary Molars Using Tricalcium Silicate Cements
Status: RECRUITING
Conditions: Primary Molar Pulpotomy
Interventions: OTHER: MTA Pro Root|OTHER: MTA HP Repair|OTHER: Biodentine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dynamic Needle Tip Positioning Modification Technique in Short Axis Approach
Status: RECRUITING
Conditions: Dynamic Needle Tip Positioning|Short Axis|Arterial Cannulation|Long Axis
Interventions: OTHER: Dynamic Needle Tip Positioning Technique in Short Axis Approach (DNTP - SA)|OTHER: Long Axis Approach (LA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Root Coverage With Acellular Dermal Matrix and Bovine Derived Osseous
Status: COMPLETED
Conditions: Recession, Gingival
Interventions: PROCEDURE: Flap Surgery for root coverage with Alloderm and xenograft|PROCEDURE: Tunnel Surgery for root coverage with Alloderm and xenograft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Primary Anatomical Versus Primary Electrophysiological Approach in Circumferential Pulmonary Vein Ablation
Status: UNKNOWN
Conditions: Paroxysmal Atrial Fibrillation
Interventions: PROCEDURE: primary electrophysiological approach|PROCEDURE: primary anatomical approach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Cancer of the Head of the Pancreas: Early Surgery or Preoperative Biliary Drainage?
Status: WITHDRAWN
Conditions: Pancreatic Cancer|Biliary Stasis
Interventions: DEVICE: Tannenbaum Fr 10 stent or WallFlex stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Manual Therapy on Head-repositioning Accuracy and Static Postural Balance in Neck Pain Patients
Status: COMPLETED
Conditions: Neck Pain
Interventions: PROCEDURE: Manual mobilization on cervical spine|PROCEDURE: Infra-red therapy with self exercise pamphlet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: JAB-21822 in Combination With Cetuximab in Patients With Advanced CRC and Other Solid Tumors With KRAS G12C Mutation
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Colorectal Cancer|Small Intestinal Cancer|Appendiceal Cancer
Interventions: DRUG: JAB-21822|DRUG: Cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study With an Open-label Extension Phase to Evaluate the Efficacy and Safety of Perampanel (E2007) Administered as an Adjunctive Therapy in Subjects With Refractory Partial-onset Seizures
Status: COMPLETED
Conditions: Partial-onset Seizures
Interventions: DRUG: Perampanel|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Alt-RAMEC Expansion and Protraction by EDO in Cleft Lip and Palate Patient
Status: UNKNOWN
Conditions: Cleft Lip and Palate
Interventions: DEVICE: Maxillary Expander with Differential Opening (EDO)|DEVICE: Petit Face Mask
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Establishing a Tumor Registry for Patients With Neuroendocrine Carcinoma of the Cervix
Status: RECRUITING
Conditions: Cervical Large Cell Neuroendocrine Carcinoma|Cervical Neuroendocrine Carcinoma|Cervical Small Cell Carcinoma|Cervical Undifferentiated Carcinoma|Stage I Cervical Cancer AJCC v8|Stage IA Cervical Cancer AJCC v8|Stage IA1 Cervical Cancer AJCC v8|Stage IA2 Cervical Cancer AJCC v8|Stage IB Cervical Cancer AJCC v8|Stage IB1 Cervical Cancer AJCC v8|Stage IB2 Cervical Cancer AJCC v8|Stage II Cervical Cancer AJCC v8|Stage IIA Cervical Cancer AJCC v8|Stage IIA1 Cervical Cancer AJCC v8|Stage IIA2 Cervical Cancer AJCC v8|Stage IIB Cervical Cancer AJCC v8|Stage III Cervical Cancer AJCC v8|Stage IIIA Cervical Cancer AJCC v8|Stage IIIB Cervical Cancer AJCC v8|Stage IV Cervical Cancer AJCC v8|Stage IVA Cervical Cancer AJCC v8|Stage IVB Cervical Cancer AJCC v8
Interventions: OTHER: Follow-Up|OTHER: Medical Chart Review
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Cytisine Compared to Combination NRT in Relapsed Smokers
Status: TERMINATED
Conditions: Smoking Cessation|Coronary Artery Disease
Interventions: DRUG: Cytisine|DRUG: Nicoderm C-Q Transdermal Product|DRUG: Nicorette Lozenge Product
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Combination Chemotherapy Regimens in Treating Patients With Stage III or Stage IV Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: BIOLOGICAL: bleomycin sulfate|BIOLOGICAL: filgrastim|BIOLOGICAL: pegfilgrastim|DRUG: ABVD regimen|DRUG: BEACOPP regimen|DRUG: cyclophosphamide|DRUG: dacarbazine|DRUG: doxorubicin hydrochloride|DRUG: etoposide|DRUG: prednisone|DRUG: procarbazine hydrochloride|DRUG: vinblastine sulfate|DRUG: vincristine sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study Assessing the Efficacy of Etoposide Free Chemotherapy Plus Durvalumab (MEDI4736) in First Line Extensive Disease Small Cell Lung Cancer (SCLC)
Status: RECRUITING
Conditions: Small Cell Lung Cancer Extensive Stage
Interventions: DRUG: Carboplatin + Paclitaxel + Durvalumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Auditory Control Enhancement (ACE) in Schizophrenia
Status: RECRUITING
Conditions: Auditory Hallucinations
Interventions: DEVICE: Transcranial Direct Current Stimulation (tDCS)|BEHAVIORAL: Auditory Cognitive Control Training (ACCT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: S-1 and Irinotecan in Treating Patients Who Are Undergoing Surgery for Locally Advanced Stomach Cancer
Status: UNKNOWN
Conditions: Gastric Cancer
Interventions: DRUG: irinotecan hydrochloride|DRUG: tegafur-gimeracil-oteracil potassium|PROCEDURE: adjuvant therapy|PROCEDURE: conventional surgery|PROCEDURE: neoadjuvant therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CD30 CAR for Relapsed/Refractory CD30+ T Cell Lymphoma
Status: RECRUITING
Conditions: Peripheral T Cell Lymphoma
Interventions: BIOLOGICAL: ATLCAR.CD30 T cells|DRUG: Bendamustine|DRUG: Fludarabine|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Ryanodex® (EGL-4104) as Adjuvant Treatment in Subjects With Exertional Heat Stroke (EHS)
Status: COMPLETED
Conditions: Heat Stroke
Interventions: DRUG: Dantrolene sodium for injectable suspension
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of SY-201 Ophthalmic Solution in Subjects With Dry Eye Disease
Status: COMPLETED
Conditions: Dry Eye Disease
Interventions: DRUG: SY-201 Ophthalmic Solution 2.0%|DRUG: SY-201 Ophthalmic Solution 1.0%|DRUG: SY-201 Ophthalmic Solution 0.5%|DRUG: SY-201 Ophthalmic Solution Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Can Single-Injection Adductor Canal Blocks Improve PostOp Pain Relief in Patients Undergoing Total Knee Arthroplasty?
Status: ACTIVE_NOT_RECRUITING
Conditions: Pain Management
Interventions: OTHER: ACB Control - 20 ml saline injection for ACB|DRUG: ACB Study - 20 ml 0.5% Ropivacaine for Adductor Canal Block|DRUG: Local infiltration - 100 mLs of a solution containing: Ropivacaine + Epinephrine + Ketorolac + Clonidine + 0.9% Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Comparative Study of New Medications for Psychosis in Adolescents
Status: COMPLETED
Conditions: Psychotic Disorders|Schizophrenia|Schizophreniform Disorders|Schizoaffective Disorders
Interventions: DRUG: quetiapine|DRUG: olanzapine|DRUG: risperidone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exploratory Dose Ranging Study Assessing APH-1501 for the Treatment of Opioid Addiction
Status: NOT_YET_RECRUITING
Conditions: Addiction|Opioid Dependence|Opioid Withdrawal
Interventions: DRUG: APH-1501|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Rapid Ventricular Pacing During Cerebral Aneurysm Surgery: a Retrospective Study Concerning the Safety for Heart and Brain
Status: COMPLETED
Conditions: Cardiac Pacing, Artificial|Aneurysm, Brain|Arteriovenous Malformations, Cerebral
Interventions: PROCEDURE: Rapid ventricular pacing (RVP)|PROCEDURE: No rapid ventricular pacing
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Standard of Care Study of Patients With Major Depressive Disorder Who Have Had an Inadequate Response to a Selective Serotonin Reuptake/Serotonin-Norepinephrine Reuptake Inhibitor Antidepressant
Status: TERMINATED
Conditions: Depressive Disorder, Major
Interventions: OTHER: Standard of Care (SOC)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of TLR9 Agonist Vidutolimod (CMP-001) in Combination With Nivolumab vs. Nivolumab
Status: ACTIVE_NOT_RECRUITING
Conditions: Melanoma
Interventions: DRUG: Vidutolimod (CMP-001)|BIOLOGICAL: Nivolumab|OTHER: [18F]F-AraG PET/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of Approved and Investigational Contact Lenses
Status: COMPLETED
Conditions: Visual Disorder
Interventions: DEVICE: Investigational Contact Lenses (Test)|DEVICE: Marketed Contact Lenses (Control)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Fentanyl Administered Intraorally for Rapid Treatment of Orthopedic Pain
Status: COMPLETED
Conditions: Pain, Fracture, Sprain
Interventions: DRUG: Fentanyl|DRUG: Lansoprazole|DRUG: Oxycodone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Abbott Laboratories Alinity s Blood Screening Assays - Clinical Evaluation Protocol
Status: COMPLETED
Conditions: Healthy
Interventions: DEVICE: Alinity s HBsAg and Alinity s HBsAg Confirmatory Assay|DEVICE: Alinity s HTLV I/II Assay|DEVICE: Alinity s Anti-HCV Assay|DEVICE: Alinity s HIV Ag/Ab Combo Assay|DEVICE: Alinity s Anti-HBc Assay|DEVICE: Alinity s Chagas Assay
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Study to Evaluate the Effects of Tempol (MBM-02) in COVID-19 Patients.
Status: TERMINATED
Conditions: Covid19
Interventions: DRUG: Tempol|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Muscle Weakness in Critically Ill Patients
Status: TERMINATED
Conditions: Critical Illness|Respiratory Failure|Myopathy|Weakness
Interventions: DEVICE: Sham Treatment|DEVICE: Electrical stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Gene Transfer Therapy for Treating Children and Adults With Limb Girdle Muscular Dystrophy Type 2D (LGMD2D)
Status: COMPLETED
Conditions: Muscular Dystrophies
Interventions: GENETIC: rAAV1.tMCK.human-alpha-sarcoglycan- First cohort|GENETIC: Genetic: rAAV1.tMCK.human-alpha-sarcoglycan- Second cohort
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mobile Phone SMS Messages and Automated Calls in Improving Vaccine Coverage Among Children in Pakistan
Status: UNKNOWN
Conditions: Tuberculosis|Polio|Diphtheria|Pertussis|Tetanus|Haemophilus Influenzae Type b Infection|Hepatitis B|Pneumococcal Infection
Interventions: BEHAVIORAL: SMS messages and automated calls
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Supplemental Feeding Tube Devices in Breastfeeding Success and Mother's Breastfeeding Self-Efficacy
Status: COMPLETED
Conditions: Breastfeeding|Feeding Disorder Neonatal
Interventions: DEVICE: Supplemental Feeding Tube Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Comparative Study of the Efficacy of Transcatheter Arterial Chemoembolization (TACE) and Transcatheter Arterial Pegylated Interferon Embolization (TAIE) for Liver Cancer
Status: UNKNOWN
Conditions: Carcinoma, Hepatocellular
Interventions: PROCEDURE: Transcatheter Arterial Chemoembolization (TACE)|PROCEDURE: Transcatheter Arterial Pegylated Interferon Embolization (TAIE)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Metformin to Reduce Airway Glucose in COPD Patients
Status: UNKNOWN
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Metformin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Hyperphosphorylated Tau PET Binding in Primary Progressive Aphasia and Frontotemporal Dementia
Status: RECRUITING
Conditions: Primary Progressive Aphasia|Behavioral Variant of Frontotemporal Dementia|Frontotemporal Dementia, Behavioral Variant
Interventions: DRUG: F-18 AV 1451
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Clinical Evaluation, Organic Response in Obesity Patients Subjected to Vertical Videolaparoscopy Gastroplasty With or Without Perioperative Cares Recommended by the Acerto Project. Randomized Study.
Status: COMPLETED
Conditions: To Evaluate Clinical Results, Insulin Resistance and Inflammatory Response to Trauma in Morbidly Obese Patients
Interventions: OTHER: ACERTO protocol vs Traditional care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Influence of Abutment Angulation on Implant Failure in Immediately Placed and Restored Implants in the Esthetic Zone Using Computer Aided Surgical Guides: RCT
Status: COMPLETED
Conditions: Immediate Dental Implants
Interventions: OTHER: Angled Abutment|OTHER: straight abutment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: An Open-Label Study to Investigate the Safety of Single and Multiple Ascending Doses in Children and Adolescents With Dravet Syndrome
Status: COMPLETED
Conditions: Dravet Syndrome
Interventions: DRUG: STK-001 - Single Ascending Doses|DRUG: STK-001 - Multiple Ascending Doses
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Virtual Reality Distraction From Procedural Pain in Children
Status: COMPLETED
Conditions: Exostosis of Elbow|Upper Extremity Fracture|Burn; Arm|Burn Scald
Interventions: DEVICE: Immersive Virtual Reality
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Helmet NIV vs. CPAP vs. High-flow Nasal Oxygen in Hypoxemic Respiratory Failure
Status: RECRUITING
Conditions: Respiratory Failure|Hypoxemic Respiratory Failure
Interventions: DEVICE: Noninvasive respiratory support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Relaxation and Stretching Exercises on Pain and Quality of Life in Women With Primary Dysmenorrhea
Status: ENROLLING_BY_INVITATION
Conditions: Primary Dysmenorrhea
Interventions: OTHER: Stretching|OTHER: Relaxation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety Study of AMG 557 in Subjects With Lupus Arthritis
Status: COMPLETED
Conditions: Lupus Arthritis, Systemic Lupus Erythematosus
Interventions: DRUG: AMG 557|DRUG: Matching Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Anterior Cross Bite Treatment on Children's Speech Performance
Status: RECRUITING
Conditions: Cross Bite|Malocclusion|Speech|Quality of Life
Interventions: DEVICE: removable anterior expansion screw|DIAGNOSTIC_TEST: Speech and language evaluation|OTHER: Oral Health Related Quality of Life (OHRQoL) Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I Study to Compare the Pharmacokinetics, Pharmacodynamics, and Safety Between CT-P41 and US-licensed Prolia in Healthy Male Subjects
Status: COMPLETED
Conditions: Healthy Subject
Interventions: BIOLOGICAL: CT-P41|BIOLOGICAL: US-licensed Prolia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Cardioprotective Effects of Freeze Dried Grape Powder on Blood Pressure and Plasma Lipids/Lipoproteins
Status: TERMINATED
Conditions: Cardiovascular Risk Factor
Interventions: DIETARY_SUPPLEMENT: Grape Powder|DIETARY_SUPPLEMENT: Placebo Powder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: PK and PD Study After Single Dose, Intravenous Administration of Two Epoetin Alfa, Eritromax and Eprex, in Healthy Subjects
Status: UNKNOWN
Conditions: Healthy
Interventions: DRUG: Epoetin Alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aminophylline to Prevent Acute Kidney Injury in Children After Cardiac Surgery
Status: COMPLETED
Conditions: Acute Kidney Injury
Interventions: DRUG: Aminophylline|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy CLAGE-Ven Sequential With Reduced Intensity Conditioning for Refractory Acute Myelodi Leukemia
Status: RECRUITING
Conditions: Refractory Leukemia
Interventions: DRUG: CALGE-VEN- RIC-conditioning
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Statin and Post-interventional Coronary Microcirculation Dysfunction
Status: UNKNOWN
Conditions: Coronary Artery Disease
Interventions: DRUG: Atorvastatin, pre-treatment 80 mg/day for 4 days before PCI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Patient Outcomes With Endoscopic Versus Open Carpal Tunnel Release
Status: COMPLETED
Conditions: Carpal Tunnel Syndrome
Interventions: PROCEDURE: endoscopic carpal tunnel release|PROCEDURE: open carpal tunnel release
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nebulized Heparin and Salbutamol in Mechanically Ventilated Patients With AECOPD
Status: COMPLETED
Conditions: Mechanically Ventilated Patients
Interventions: DRUG: Nebulized heparin and salbutamol|DRUG: Nebulized salbutamol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Hemoglobin Based Oxygen Therapeutics in Elective Percutaneous Coronary Revascularization
Status: COMPLETED
Conditions: Coronary Occlusion|Acute Coronary Syndrome
Interventions: DRUG: Hemoglobin Based Oxygen Carrier-201 (HBOC-201, Hemopure)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Probiotic Administration and Perennial Allergic Rhinitis
Status: COMPLETED
Conditions: Rhinitis, Allergic, Perennial
Interventions: DIETARY_SUPPLEMENT: Lactobacillus paracasei probiotic strain|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Safety Study of Combination Treatment With Avonex and Placebo-Controlled Dosing of Topamax in Relapsing-Remitting Multiple Sclerosis
Status: UNKNOWN
Conditions: Multiple Sclerosis
Interventions: DRUG: Avonex and Topamax
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study of Envofolimab and BD0801 With/Without Chemotherapy in Patients With Advanced Solid Tumors
Status: TERMINATED
Conditions: Advanced Solid Tumor
Interventions: DRUG: Envofolimab|DRUG: BD0801|DRUG: Docetaxel|DRUG: Irinotecan|DRUG: Leucovorin calcium|DRUG: 5-Fluorouridine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Meditation Effects on Brain Function in Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: BEHAVIORAL: Meditation Intervention A|BEHAVIORAL: Meditation Intervention B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Efficacy Study of Phytotherapy "Raylis" In Congestive Processes Of The Pelvic Organs (Prostatostasis)
Status: UNKNOWN
Conditions: Congestive Processes Of The Pelvic Organs (Prostatostasis)|Erectile Dysfunction|Sexual Function
Interventions: DRUG: "Raylis"|OTHER: standard prostatostasis therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Study of Neo-adjuvant Chemoradiotherapy for Squamous Cell Esophageal Cancer
Status: UNKNOWN
Conditions: Esophageal Cancer|Chemoradiation|Surgery
Interventions: RADIATION: radiotherapy|PROCEDURE: Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Omalizumab (Xolair) and Allergy Shots For the Treatment of Seasonal Allergies
Status: COMPLETED
Conditions: Hay Fever|Hypersensitivity|Allergy|Rhinitis
Interventions: BIOLOGICAL: omalizumab|BIOLOGICAL: Placebo omalizumab|BIOLOGICAL: Ragweed rush immunotherapy (RIT)|BIOLOGICAL: Placebo rush immunotherapy (RIT)|BIOLOGICAL: Ragweed immunotherapy (IT)|BIOLOGICAL: Placebo immunotherapy (IT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Epithelium-on Cross-linking Versus Observation of Fellow Eyes of Patients With Unilateral Clinically Evident Keratoconus
Status: COMPLETED
Conditions: Keratoconus
Interventions: PROCEDURE: Epithelium-on corneal cross-linking (epi-on CXL)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Evaluate the Safety, Tolerability, and Drug Levels of BMS-986337 When Taken by Mouth by Healthy Participants
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: BMS-986337|OTHER: BMS-986337 Placebo|BIOLOGICAL: Famotidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1/2 Multicenter Dose Escalation and Expansion Study Of NKTR-214 In Subjects With Locally Advanced Or Metastatic Solid Tumors
Status: COMPLETED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: NKTR-214
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Microbiota Intervention to Change the Response of Parkinson's Disease
Status: SUSPENDED
Conditions: Parkinson Disease
Interventions: DRUG: Rifaximin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Yeast Cells as Antioxidant-Producing Probiotics
Status: COMPLETED
Conditions: Infertility, Male
Interventions: DIETARY_SUPPLEMENT: Vit E|DIETARY_SUPPLEMENT: Yeast|DIETARY_SUPPLEMENT: Vit C 1|DIETARY_SUPPLEMENT: Vit C 2|DIETARY_SUPPLEMENT: Vit C 3
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Influence of Fluid Removal Using Continuous Venovenous Hemofiltration (CVVH) on Intra-abdominal Pressure and Kidney Function
Status: WITHDRAWN
Conditions: Critically Ill|Intra-Abdominal Hypertension|Abdominal Compartment Syndrome|Acute Kidney Injury
Interventions: PROCEDURE: CVVH|PROCEDURE: ultrafiltration|PROCEDURE: ultrafiltration control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1/2 Study of Ramucirumab Plus Nivolumab in Participants With Gastric or GEJ Cancer
Status: COMPLETED
Conditions: Gastric Cancer|Gastroesophageal Junction Region (GEJ) Cancer
Interventions: BIOLOGICAL: Ramucirumab|BIOLOGICAL: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Walking Apnea at Low Lung Volume on Hypoalgesia, Cardiovascular Function and Respiratory Function
Status: RECRUITING
Conditions: Pain|Hypoxia|Hypercapnia|Apnea
Interventions: OTHER: Voluntary apnoea
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Passiflora Extract for Benzodiazepine Withdrawal
Status: UNKNOWN
Conditions: Benzodiazepine Withdrawal (Disorder)
Interventions: DRUG: Passiflora incarnata|DRUG: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Early Intervention Following Sexual Assault
Status: RECRUITING
Conditions: Ptsd|Alcohol Use Disorder|Sexual Assault and Rape
Interventions: BEHAVIORAL: Written Exposure Therapy Integrated with Cognitive Behavioral Therapy for Alcohol Use Disorder|BEHAVIORAL: Written Exposure Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fludeoxyglucose F 18-PET Imaging for Early Detection of Residual Disease in Patients Undergoing Radiofrequency Ablation of Liver Metastases From Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer|Metastatic Cancer
Interventions: PROCEDURE: positron emission tomography|PROCEDURE: radiofrequency ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation of the Impact of a Digital Tool MEDIASCREEN of Preventive Information for Patients on the Knowledge of the Risk of Pressure Sores Acquired During a Hospitalization
Status: RECRUITING
Conditions: Pressure Sore
Interventions: OTHER: Numeric prevention|OTHER: Paper prevention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Impact of Stent Length on Short Term Outcomes in Patients With Stable Coronary Disease Undergoing PCI
Status: UNKNOWN
Conditions: Stable Chronic Angina
Interventions: DEVICE: Stent more than 26 mn length|DEVICE: Stent equal to or less than26 mn length
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p