pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Platform Study of Novel Immunotherapy Products in Participants With Previously Treated Unresectable or Metastatic Cutaneous Melanoma
Status: WITHDRAWN
Conditions: Unresectable Cutaneous Melanoma|Metastatic Cutaneous Melanoma
Interventions: COMBINATION_PRODUCT: Sintilimab + IBI110
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Clinical Efficacy Between Multi-layer Bandage Pressure Therapy and Gradient Pressure Elastic Stocking Treatment After Endovenous Radiofrequency Ablation
Status: RECRUITING
Conditions: Vascular Diseases, Peripheral|Venous Insufficiency of Leg|Varicose Veins of Lower Limb
Interventions: PROCEDURE: Questionnaires
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: JS001 Combination Therapy in NSCLC Negative Driving Gene After First-line Chemotherapy.
Status: UNKNOWN
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: Toripalimab injection combine with Axitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transcranial Electrical Stimulation (TCES) / Cerebral Blood Flow (CBF) / Xenon Under Computerized Tomography (Xe/CT)
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DEVICE: TCES
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: DRug-coAted Balloon Compared With cuttinG balloON in Treatment of Arteriovenous Fistula Stenosis
Status: RECRUITING
Conditions: Arteriovenous Fistula|Angioplasty, Balloon|Hemodialysis Access Failure
Interventions: PROCEDURE: Endovascular therapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Family-Focused Therapy for Youth With Early-Onset Bipolar or Psychotic Disorders
Status: COMPLETED
Conditions: Mood Disorders|Psychotic Disorders
Interventions: BEHAVIORAL: High Intensity Training|BEHAVIORAL: Low Intensity Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Myofascial Reorganization on Performance, and Biomechanical, Viscoelastic, and Thermographic Properties of Athletes
Status: RECRUITING
Conditions: Healthy
Interventions: OTHER: Myofascial Reorganization|OTHER: PLACEBO Myofascial Reorganization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Osimertinib and Necitumumab in Treating Patients With EGFR-Mutant Stage IV or Recurrent Non-small Cell Lung Cancer Who Have Progressed on a Previous EGFR Tyrosine Kinase Inhibitor
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Lung Non-Small Cell Carcinoma|Recurrent Lung Non-Small Cell Carcinoma|Stage IV Lung Cancer AJCC v8
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|PROCEDURE: Echocardiography|PROCEDURE: Magnetic Resonance Elastography|PROCEDURE: Multigated Acquisition Scan|BIOLOGICAL: Necitumumab|DRUG: Osimertinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Health Belief Model Education on Water Intake in the Elderly (HBM-Water Study)
Status: NOT_YET_RECRUITING
Conditions: Dehydration|Water Consumption in Elderly
Interventions: BEHAVIORAL: Health Belief Model Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: FIBRotic Interstitial Lung Disease With Nocturnal hypOXaemia and EXercise Induced desaTuRAtion
Status: NOT_YET_RECRUITING
Conditions: Interstitial Lung Disease|Fibrosis Lung|Pulmonary Hypertension
Interventions: OTHER: Prospective
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Anti-Inflammatory Effect of Tocotrienol Supplementation in Subjects With Moderately Elevated Inflammation
Status: UNKNOWN
Conditions: Inflammation|Cardiovascular Risk Factor
Interventions: DIETARY_SUPPLEMENT: Tocotrienol-rich fraction|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Clinical Efficacy and Safety Study of OHB-607 in Preventing Bronchopulmonary Dysplasia in Extremely Premature Infants
Status: RECRUITING
Conditions: Bronchopulmonary Dysplasia|Chronic Lung Disease of Prematurity|Intraventricular Hemorrhage|Retinopathy of Prematurity (ROP)
Interventions: DRUG: OHB-607
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: First Line Bio-immunotherapy With Thymosin Alpha 1 in Patients With Sensitizing EGFR Mutation Positive Non Small Cell Lung Cancer Who Are Taking Standard of Care Therapy
Status: UNKNOWN
Conditions: EGFR Mutation Positive Non Small Cell Lung Cancer
Interventions: DRUG: Thymalfasin (Thymosin alpha 1, Ta1)|DRUG: SoC (tyrosine kinase inhibitor)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ARTS - AVODART After Radical Therapy For Prostate Cancer Study
Status: COMPLETED
Conditions: Neoplasms, Prostate|Prostate Cancer After a Radical Treatment
Interventions: DRUG: Avodart|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Toripalimab Combined With Chemoradiotherapy in Patients With Locoregionally-advanced Nasopharyngeal Carcinoma
Status: NOT_YET_RECRUITING
Conditions: Nasopharyngeal Neoplasms
Interventions: DRUG: Toripalimab|DRUG: Albumin-bound Paclitaxel|DRUG: Cisplatin|RADIATION: intensity-modulated radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Paeoniflorin Combination of Hepatoprotective Drugs Versus Hepatoprotective Drugs Only for Auto-immune Hepatitis
Status: WITHDRAWN
Conditions: Hepatitis, Autoimmune
Interventions: DRUG: Paeoniflorin + phosphatidylcholine or silymarin|DRUG: Phosphatidylcholine or silymarin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessing the Effect of Cool Roofs on Health Using Smartwatches: a Global Multi-center Study
Status: NOT_YET_RECRUITING
Conditions: Heart Rate|All-day Steps|Distance Walked|Active Minutes|Moderate-intensity Activity Minutes|Vigorous-intensity Activity Duration|Sleep Quantity|Time in Sleep Stages|Awake Duration|Sleep Score
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: This Study Assessed the Impact of Diet on Gastric Emptying Time and Metabolic Flexibility
Status: COMPLETED
Conditions: Obesity|Diabetes Mellitus, Type 2|Appetitive Behavior
Interventions: OTHER: Raw Corn Starch|OTHER: No Raw Corn Starch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Remiazolam Combined With Esketamine in Painless Bidirectional Endoscopy in Children
Status: COMPLETED
Conditions: Drug Effect
Interventions: DRUG: Remimazolam|DRUG: Esketamine|DRUG: Propofol|DRUG: remifentanil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Pharmacokinetic Study of LMN-101 in Healthy Volunteers
Status: COMPLETED
Conditions: Campylobacter Jejuni Infection
Interventions: BIOLOGICAL: LMN-101
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Dexmedetomidine on the Minimum Alveolar Concentration of Sevoflurane
Status: RECRUITING
Conditions: Pediatric Anesthesia
Interventions: DRUG: Dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of Chitosan Scaffold and Mineral Trioxide Aggregate Pulpotomy in Mature Permanent Molars With Irreversible Pulpitis
Status: COMPLETED
Conditions: Pulpitis - Irreversible
Interventions: DRUG: Chitosan scaffold/ MTA pulp dressing material|DRUG: MTA pulp dressing material
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Therapeutic Equivalence Study of Two Metronidazole 1%Topical Gel Treatments for Patients With Rosacea
Status: COMPLETED
Conditions: Rosacea
Interventions: DRUG: Metronidazole Topical Gel 1%|DRUG: Metronidazole Topical Gel 1% (Metrogel)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Endothelium Dependent and Non-dependent Vasodilatation in Human Gingiva
Status: COMPLETED
Conditions: Vasodilatation|Oral Soft Tissue Conditions
Interventions: DRUG: Nitroglycerin|DRUG: Acetylcholine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Comparison of Intranasal Midazolam and Nitrous Oxide (N2O) Minimal Sedation for Minor Procedures in a Pediatric Emergency Department
Status: COMPLETED
Conditions: Conscious Sedation|Simple Lacerations Less Than 4 cm|Lumbar Punctures|Minor Incision Drainage of Abscesses Not Requiring Extensive Debridement
Interventions: DRUG: Nitrous Oxide|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Does Steroid Plus CO2 Laser Improve Lichen Sclerosus Symptoms Compared to Steroids Alone?
Status: RECRUITING
Conditions: Vulvar Lichen Sclerosus
Interventions: DEVICE: MonaLisa Touch|DRUG: Topical steroid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: COmparison of White Light and Linked COlor Imaging for Detection of RIght COlon Polyps
Status: COMPLETED
Conditions: Adenoma Colon|Colon Polyp|Colonoscopy
Interventions: PROCEDURE: exploration in white light (WLI)|PROCEDURE: Exploration in LCI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Cognitive and Psychophysiological Effects of Delta-9-Tetrahydrocannabinol in Bipolar Disorder
Status: TERMINATED
Conditions: Delta-9-Tetrahydroncannabinol|Bipolar Disorder|Healthy Controls
Interventions: DRUG: 4 mg Delta-9-THC|DRUG: Placebo|DRUG: 2 mg Delta-9-THC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Estimated Glomerular Filtration Rate After Kidney Transplantation - the Formula MDRD, CKD-EPI or Cockroft-Gault?
Status: COMPLETED
Conditions: Renal Function Disorder
Interventions: OTHER: Estimating of formula MDRD, CKD-EPI, Cockroft-Gault,|DEVICE: Tanita BC 418- Bioelectrical impedance analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of Patient-Reported Outcomes Measurement Information System (PROMIS)-29 v2.1 for Postpartum Women
Status: NOT_YET_RECRUITING
Conditions: Well-Being, Psychological
Interventions: OTHER: PROMIS-29 v2.1 (Patient-Reported Outcomes Measurement Information System)|OTHER: WHOQoLBREF (World Health Organization Quality of Life Brief Version)|OTHER: EQ-5D-3L1 (not an acronym)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Atezolizumab Immunotherapy With or Without Tiragolumab for Patients With Unresectable Stage III NSCLC
Status: RECRUITING
Conditions: NSCLC
Interventions: DRUG: Atezolizumab|DRUG: Tiragolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Long Acting Buprenorphine Injection Compared to Sublingual Buprenorphine/Naloxone Films
Status: WITHDRAWN
Conditions: Opioid Use
Interventions: DRUG: Suboxone® SL|DRUG: Sublocade®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Cord Blood-derived Cytokine-induced Killer Cells in Patients With Solid Tumor After Radical Resection
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma|Renal Cell Carcinoma|Lung Cancer
Interventions: BIOLOGICAL: cytokine induced killer cell
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Comparing SCD411 and Eylea® in Subjects With Wet Age-related Macular Degeneration (AMD)
Status: COMPLETED
Conditions: Wet Age-related Macular Degeneration|Neovascular Age-related Macular Degeneration
Interventions: DRUG: SCD411|DRUG: Aflibercept
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Residual Myopic Refraction After 6 Months on Pseudophakic Patients Using Relex-Smile
Status: ENROLLING_BY_INVITATION
Conditions: Pseudophakia|Myopia
Interventions: PROCEDURE: Relex-Smile surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of Giomer Based Injectable Resin Composite Versus Resin Modified Glass Ionomer in Class V Carious Cavities Over 18-months.
Status: COMPLETED
Conditions: Class V Dental Caries
Interventions: DEVICE: Giomer based injectable resin composite|DEVICE: Resin modified glass ionomer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Anxiety Associated With the Use of the Electrocardiogram Function in Smart Watches
Status: COMPLETED
Conditions: Mental Health Wellness 1|Anxiety Disorders|Depression
Interventions: DEVICE: Electrocardiogram (ECG) feature in smart watches
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Efficacy Study in Patients With Major Depressive Disorder
Status: COMPLETED
Conditions: Depressive Disorder
Interventions: DRUG: GSK163090 1 mg|DRUG: GSK163090 Placebo|DRUG: GSK163090 3 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Modifying a Telephone Based Care Program to Assess for Self-Neglect
Status: UNKNOWN
Conditions: Self Neglect
Interventions: BEHAVIORAL: Benjamin Rose Institute Care Consultation (BRI-CC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Prospective Study of Surgical Treatment Strategies for Goal B Type Basilar Invagination
Status: RECRUITING
Conditions: Basilar Invagination|Prospective Study|Surgical Outcome
Interventions: PROCEDURE: Posterior fossa decompression|PROCEDURE: Posterior Compression-Distraction-Reduction-Fixation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pancreatic Stent to Prevent Leak After Distal Pancreatectomy
Status: WITHDRAWN
Conditions: Pancreatic Surgery|Pancreatic Duct Stenting|Pancreatic Cancer|Distal Pancreatectomy|Pancreatic Diseases|Pancreatic Cyst|Pancreatic Ducts
Interventions: PROCEDURE: Pancreatic duct stenting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Impact of Different Citrate Concentrations as Locking Solutions on Development of Biofilm and Function of Hemodialysis Catheters
Status: UNKNOWN
Conditions: End-Stage Kidney Disease|Renal Dialysis|Central Venous Catheter|Biofilms
Interventions: OTHER: 4% sodium citrate|OTHER: 30% sodium citrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effects of Kinesiotaping and Mulligan Tapping on PFPS
Status: COMPLETED
Conditions: Patellofemoral Pain Syndrome
Interventions: OTHER: kinesiotaping group|OTHER: mulligan taping group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Paclitaxel With or Without Viral Therapy in Treating Patients With Recurrent or Persistent Ovarian Epithelial, Fallopian Tube, or Primary Peritoneal Cancer
Status: COMPLETED
Conditions: Recurrent Fallopian Tube Carcinoma|Recurrent Ovarian Carcinoma|Recurrent Primary Peritoneal Carcinoma
Interventions: OTHER: Laboratory Biomarker Analysis|DRUG: Paclitaxel|BIOLOGICAL: Pelareorep
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics of Intravenous Difelikefalin in Chinese Adult Subjects on Haemodialysis
Status: COMPLETED
Conditions: End Stage Renal Disease on Hemodialysis
Interventions: DRUG: Difelikefalin Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of LIPO-5 and ALVAC-HIV (vCP1452) as Possible HIV Vaccines
Status: COMPLETED
Conditions: HIV Infections
Interventions: BIOLOGICAL: ALVAC-HIV (vCP1452)|BIOLOGICAL: LIPO-5
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Study Evaluating the Safety and Effects of MN-221 in Subjects With Moderate to Severe Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: MN-221|DRUG: MN-221|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Body Project: Comparing the Effectiveness of an In-person and Virtually Delivered Intervention.
Status: ACTIVE_NOT_RECRUITING
Conditions: Eating Disorders
Interventions: BEHAVIORAL: Peer Led Group Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effectiveness of Community-Level Behavioral and Biomedical Interventions for Reducing HIV/STIs in Men in Peru
Status: COMPLETED
Conditions: HIV Infections|Sexually Transmitted Infections
Interventions: BEHAVIORAL: Enhanced Partner Therapy (EPT)|BEHAVIORAL: Communidades Positivas (CPOS)|BEHAVIORAL: Standard Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Naptumomab Estafenatox (NAP) in Combination With Docetaxel Following Obinutuzumab Pretreatment in Subjects With Checkpoint Inhibitor Pretreated Advanced or Metastatic NSCLC
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: NAP (Naptumomab estafenatox)|DRUG: Docetaxel|DRUG: Obinutuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Assessing Efficacy of Plasmatherapy in Septic Shock-induced Coagulopathy: Feasibility Study
Status: COMPLETED
Conditions: Septic Shock|Coagulopathy|Disseminated Intravascular Coagulation
Interventions: DRUG: OctaplasLG®|DRUG: 0.9% NaCl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Addition of Lactobacillus to Metronidazole in Treatment of CDAD
Status: WITHDRAWN
Conditions: Enterocolitis|Pseudomembranous Colitis|Antibiotic-associated Colitis
Interventions: DRUG: Lactobacillus GG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating The Efficacy And Safety Of CP-690,550 In Patients With Moderate To Severe Ulcerative Colitis
Status: COMPLETED
Conditions: Ulcerative Colitis
Interventions: DRUG: tofacitinib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study BRIMOCHOL™ PF and Carbachol PF in Subjects With Emmetropic Phakic or Pseudophakic Presbyopia
Status: COMPLETED
Conditions: Presbyopia
Interventions: DRUG: BRIMOCHOL™ PF|DRUG: Carbachol PF|DRUG: Brimonidine tartrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Louisiana State University Health Care Sciences Division (LSU HSCD) Tele-Health Projects: Adult CHF Patient Population
Status: COMPLETED
Conditions: Congestive Heart Failure
Interventions: DEVICE: Tele-health Monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: 90 DAYS: An Entertainment Education Intervention to Evaluate a Short Film About HIV Status Disclosure
Status: COMPLETED
Conditions: HIV/AIDS
Interventions: BEHAVIORAL: 90 DAYS film|BEHAVIORAL: HIV pamphlet on disclosure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Prospective, Multicenter, Randomized Controlled Study to Evaluate the Effect of INTERCEED™
Status: TERMINATED
Conditions: Subjects Scheduled to Undergo Laparoscopic Radical Resection of Rectal Carcinoma With Preventive Ileostomy
Interventions: DEVICE: INTERCEED™|DEVICE: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A FIH Study to Assess the Safety and Tolerability of NS Intravenous NS101 Infusion
Status: COMPLETED
Conditions: Neurodegenerative Diseases
Interventions: DRUG: NS101 IV infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics of Two Formulation of Tenofovir Disoproxil Fumarate
Status: COMPLETED
Conditions: Pharmacokinetic of Tenofovir in Healthy Subjects
Interventions: DRUG: Tenofovir Disoproxil Fumarate 300 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non-invasive Assessment of Intracranial Pressure Using Ocular Sonography in Patients Undergoing Laparoscopic Sleeve Gastrectomy
Status: UNKNOWN
Conditions: Optic Nerve Sheath Diameter|Laparoscopic Sleeve Gastrectomy
Interventions: DIAGNOSTIC_TEST: ultrasonographic measurement of the optic nerve sheath diameter
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Natural Antioxidant Ice-cream, Oxidative Stress and Vascular Function
Status: COMPLETED
Conditions: Vascular System Injuries
Interventions: OTHER: Antioxidant ice-cream|OTHER: Control Ice-cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Heart Rate Variability Biofeedback on College Students With Disordered Eating
Status: COMPLETED
Conditions: Eating Disorders|Eating, Binge|Anorexia Nervosa/Bulimia|Eating Disorder Binge|Heart Rate Variability|Psychological Distress|Emotion Regulation|Autonomic Nervous System
Interventions: BEHAVIORAL: Baseline survey|BEHAVIORAL: Heart rate variability biofeedback|BEHAVIORAL: Educational materials
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Phase 1 Study to Investigate the Mechanism of Action of Ipragliflozin
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: ASP1941|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Using a Bionic Leg on Physiological and Biomechanical Measures in Stroke Patients
Status: COMPLETED
Conditions: Stroke|Physical Activity|Gait, Hemiplegic
Interventions: DEVICE: Baseline Bionic Leg Assessment|OTHER: Baseline Control Condition Assessment|OTHER: Training|OTHER: Follow-up Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Prophylactic Quetiapine on Delirium Prevention in Critically Ill Patients
Status: UNKNOWN
Conditions: Delirium
Interventions: DRUG: quetiapine|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Vescell(TM) for the Treatment of Patients With Severe Anginal Syndrome With or Without Heart Failure
Status: UNKNOWN
Conditions: Angina Pectoris
Interventions: PROCEDURE: Intracoronary administration of autologous ACPs
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Tissue Samples From Women Treated With Paclitaxel for Breast Cancer on Clinical Trial CALGB-9344 or CALGB-9741
Status: COMPLETED
Conditions: Breast Cancer
Interventions: GENETIC: gene expression analysis|GENETIC: polymerase chain reaction|OTHER: laboratory biomarker analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Study is Being Conducted to Evaluate the Efficacy and Safety of SHR-1316 in Combination With Chemo-radiotherapy in Patients With LS-SCLC.
Status: ENROLLING_BY_INVITATION
Conditions: Small-cell Lung Cancer
Interventions: DRUG: SHR-1316; Carboplatin; Etoposide；Radiotherapy|DRUG: Palcebo; Carboplatin; Etoposide；Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Equivalence of Azelastine Hydrochloride and Fluticasone Propionate, 137/50 mcg Nasal Spray to Dymista™
Status: UNKNOWN
Conditions: Seasonal Allergic Rhinitis
Interventions: DRUG: Azelastine hydrochloride and Fluticasone propionate|DRUG: Dymista™|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Safety and Tolerability of Sodium Thiosulfate in Patients With an ACS Undergoing CAG Via Trans-radial Approach.
Status: COMPLETED
Conditions: Acute Coronary Syndrome
Interventions: DRUG: Sodium Thiosulfate Pentahydrate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Intra-Articular Injections of Autologous Peripheral Blood Stem Cells Following Subchondral Drilling Surgery for the Treatment of Articular Cartilage Injury in the Knee
Status: COMPLETED
Conditions: Articular Cartilage Disorder of Knee|Articular Cartilage; Degeneration
Interventions: BIOLOGICAL: Autologous peripheral blood stem cells and hyaluronic acid|OTHER: Hyaluronic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CPD-DARA in Patients With Relapsed/Refractory Multiple Myeloma.
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: Daratumumab|DRUG: Cyclophosphamide|DRUG: Pomalidomide|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cognitive Behavioural Therapy (CBT) for Chronic Loneliness in Children and Young People
Status: UNKNOWN
Conditions: Loneliness
Interventions: OTHER: Cognitive Behavioural Therapy (CBT) for Chronic Loneliness
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Interoceptive Mechanisms of Body Image Disturbance in Anorexia Nervosa
Status: RECRUITING
Conditions: Anorexia Nervosa|Body Image Disturbance|Interoception
Interventions: BEHAVIORAL: Floatation-REST|BEHAVIORAL: IFT|BEHAVIORAL: EFT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Siremadlin Alone and in Combination With Donor Lymphocyte Infusion in Acute Myeloid Leukemia Post-allogeneic Stem Cell Transplant
Status: TERMINATED
Conditions: Acute Myeloid Leukemia|Allogeneic Stem Cell Transplantation
Interventions: DRUG: Siremadlin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Genetic Variation in Starch-digesting Enzymes on Digestibility and Glycemic Index of Cold and Hot Rice
Status: COMPLETED
Conditions: Carbohydrate Intolerance
Interventions: OTHER: Glucose|OTHER: Glucose plus lactulose|OTHER: Hot Rice|OTHER: Cold Rice
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Single Incision Laparoscopic Cholecystectomy Compared With Conventional Laparoscopic Cholecystectomy, a Randomized Controlled Clinical Study
Status: RECRUITING
Conditions: Cholecystectomy, Laparoscopic
Interventions: PROCEDURE: Laparoscopic cholecystectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dacron vs Dardik for Fem-Pop Bypass
Status: COMPLETED
Conditions: Intermittent Claudication|Arterial Occlusive Diseases|Atheroslerosis
Interventions: DEVICE: heparin-bonded and collagen coated polyster|DEVICE: Human umbilical vein femoro-popliteal bypass
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: L-carnitine and Metformin in Obese PCOS Women.
Status: COMPLETED
Conditions: PCOS
Interventions: DRUG: L-carnitine and Metformin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Trial Comparing Prevena and ActiV.A.C. System to Convetional Care After Bascom's Cleft Lift Surgery
Status: TERMINATED
Conditions: Pilonidal Disease
Interventions: DEVICE: Prevena™ og ACTIV.A.C™ Therapy System.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation Of The Treatment Effectiveness Of Glioblastoma / Gliosarcoma Through The Suppression Of The PI3K/Akt Pathway In Compared With MK-3475
Status: UNKNOWN
Conditions: Glioblastoma
Interventions: DRUG: MK - 3475|BIOLOGICAL: Suppressor of the PI3K/Akt pathways
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multiple Dose Study of UCB4940 in Subjects With Psoriatic Arthritis
Status: COMPLETED
Conditions: Psoriatic Arthritis
Interventions: DRUG: UCB4940 40 mg|DRUG: UCB4940 80 mg|DRUG: UCB4940 160 mg|DRUG: UCB4940 240 mg|DRUG: UCB4940 320 mg|DRUG: UCB4940 560 mg|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Beneficial Effect of TJ-134 for Patients With Symptomatic Pneumatosis Cystoides Intestinalis
Status: RECRUITING
Conditions: Pneumatosis Cystoides Intestinalis
Interventions: DRUG: Japanese traditional medicine group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Muscle Wasting in Children and Adolescents With Cancer
Status: UNKNOWN
Conditions: Cachexia; Cancer|Muscle Wasting|Child Development|Adolescent Development
Interventions: BEHAVIORAL: Multidisciplinary care with a personalized care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: BLQ Study: A Study of a Protease Inhibitor With Fuzeon (Enfuvirtide) in Treatment-Experienced Patients With HIV-1.
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Background ARVs|DRUG: PI|DRUG: enfuvirtide [Fuzeon]
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Different Anchorage-supported Appliances and Expansion Procedures for Face Mask Treatment
Status: COMPLETED
Conditions: Malocclusion, Angle Class III
Interventions: DEVICE: Face mask with Hybrid-Hyrax|DEVICE: Face mask with Bonded RME|PROCEDURE: Alternative Rapid Maxillary Expansion and Contraction Protocol (Alt-RAMEC)|PROCEDURE: Routine Rapid Maxillary Expansion Protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Efficacy and Safety of Monalizumab Plus Cetuximab Compared to Placebo Plus Cetuximab in Recurrent or Metastatic Head and Neck Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Squamous Cell Carcinoma of the Head and Neck
Interventions: DRUG: Monalizumab|DRUG: Cetuximab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Dapagliflozin on EChOcardiographic Measures of CarDiac StructurE and Function in Patients With CKD
Status: RECRUITING
Conditions: Chronic Kidney Diseases
Interventions: DRUG: Dapagliflozin 10 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Multiple-Dose Study to Evaluate MK-1075 in Hepatitis C Virus (HCV) Infected Participants (MK-1075-004)
Status: COMPLETED
Conditions: Hepatitis C Virus Infection
Interventions: DRUG: 200 mg MK-1075|DRUG: 400 mg MK-1075|DRUG: 800 mg MK-1075
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Soy Protein and Colorado Diet on Weight Loss and Maintenance
Status: COMPLETED
Conditions: Overweight|Obesity|Weight Loss
Interventions: DIETARY_SUPPLEMENT: Colorado Diet with soy protein foods.|BEHAVIORAL: Colorado Diet with monetary payments
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Systemic Bioavailability and Effects on 24-Hour Plasma Cortisol Profile of 6 mg Delivered Once Daily Versus 3 mg Delivered Twice Daily in Healthy Adult Male Volunteers
Status: COMPLETED
Conditions: Healthy Adult Male Volunteers
Interventions: DRUG: Beclomethasone dipropionate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Comparison of Efficacy of Metoclopramide , Promethazine and Prochloroperazine in the Treatment of Vertigo.
Status: RECRUITING
Conditions: Peripheral Vertigo
Interventions: DRUG: Metoclopramid ( 10mg), IM promethazine (25mg) , IM prochloroperazine( 12.5mg)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Anlotinib and AK105 Injection in Subjects With Gastrointestinal Tumors, Urinary System Tumors, Neuroendocrine Tumors
Status: UNKNOWN
Conditions: Gastrointestinal Tumors, Urinary System Tumors, Neuroendocrine Tumors
Interventions: DRUG: AK105|DRUG: Anlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Assess the Efficacy of Early Introduction of a Combination of Low Dose Vasopressin Analogue in Addition to Noradrenaline as a Vasopressor in Patients of Cirrhosis With Septic Shock
Status: COMPLETED
Conditions: Cirrhosis With Septic Shock
Interventions: DRUG: Low dose terlipressin|DRUG: Noradrenaline|DRUG: Noradrenaline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Statin/Vitamin D & Migraine Study
Status: COMPLETED
Conditions: Migraine
Interventions: DRUG: Simvastatin|DIETARY_SUPPLEMENT: Vitamin D|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Hypnotherapy for Prevention of Relapse in Ulcerative Colitis: a Randomised, Single-blind, Controlled Clinical Trial
Status: TERMINATED
Conditions: Ulcerative Colitis
Interventions: BEHAVIORAL: Gut focussed hypnotherapy|BEHAVIORAL: Control educational sessions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Two Methods of Olfactory Rehabilitation in Post-viral Loss of Smell: Classic and Intensive
Status: UNKNOWN
Conditions: Olfaction Disorders
Interventions: OTHER: smell the odors of the olfactory rehabilitation kit according to the classic or intensive method
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Parasitic Infections and Ulcerative Colitis: Combining Anti-parasitic and Immunomodulatory Treatments May Achieve Remission
Status: COMPLETED
Conditions: Ulcerative Colitis
Interventions: DRUG: Echinacea Extract|DRUG: MetroNIDAZOLE 500 MG Oral Tablet [Flagyl]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Efficacy and Safety of JP-1366 in the Prevention of NSAIDs-Induced Peptic Ulcers
Status: NOT_YET_RECRUITING
Conditions: Peptic Ulcer
Interventions: DRUG: JP-1366 10 mg|DRUG: Lanston Capsule 15 mg|DRUG: JP-1366 10 mg placebo|DRUG: Lanston Capsule 15 mg placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of Low-concentration Atropine for Myopia Control in Chinese Children and Adolescents
Status: NOT_YET_RECRUITING
Conditions: Myopia, Progressive
Interventions: DRUG: low concentration atropine (0.01%)|DRUG: low concentration atropine (0.025%)|DRUG: low concentration atropine (0.05%)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Influence of Two Different PEEP Niveaus and a Trendelenburg Positioning Manoeuvre on Subclavian Vein Diameter
Status: WITHDRAWN
Conditions: Insufficiency; Cardiac, Complicating Surgery
Interventions: OTHER: neutral positioning, PEEP 0 cm H2O|OTHER: neutral positioning, PEEP 5cm H2O|OTHER: neutral positioning, PEEP 10cm H2O|OTHER: Trendelenburg positioning -20°, PEEP 0 cmH2O|OTHER: Trendelenburg positioning -20°, PEEP 5 cmH2O|OTHER: Trendelenburg positioning -20°, PEEP 10 cmH2O
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Extension Study of 1.0mg Dose Letrozole Therapy in Postmenopausal Patients With Breast Cancer
Status: COMPLETED
Conditions: Postmenopausal Women With Advanced Breast Cancer
Interventions: DRUG: Letrozole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cerebral Haemodynamic Changes During Cognitive Testing: A fTCD Study
Status: COMPLETED
Conditions: Mild Cognitive Impairment|Alzheimer Disease|Vascular Dementia|Healthy Controls
Interventions: OTHER: Transcranial doppler ultrasonography|OTHER: Blood pressure monitoring|OTHER: Heart rate monitoring|OTHER: End tidal CO2 monitoring|OTHER: Addenbrooke's cognitive examination
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Occupational Therapist-Led Work Intervention in Facilitating Work Maintenance or Re-entry to the Workforce in Patients With Stage I to III Breast Cancer Undergoing Chemotherapy
Status: TERMINATED
Conditions: Breast Cancer Stage I|Breast Cancer Stage III|Breast Cancer Stage II|Breast Cancer Stage IIA|Breast Cancer Stage IIB|Breast Cancer Stage IIIA|Breast Cancer Stage IIIB|Breast Cancer Stage IIIc|Breast Cancer
Interventions: BEHAVIORAL: Occupational Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Nocturnal Mouth Guards, SOVA vs. Standard Acrylic Orthotic; Phase IV
Status: COMPLETED
Conditions: Sleep Bruxism|Tooth Wear
Interventions: DEVICE: SOVA Bite Splint|DEVICE: Michigan Bite Splint
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Average Volume-assured Pressure Support as Rescue Therapy in Obesity Hypoventilation Syndrome
Status: COMPLETED
Conditions: Obesity Hypoventilation Syndrome (OHS)
Interventions: DEVICE: AVAPS study was performed within 1 week of the CPAP titration attempt failure, using the auto-titrating EPAP (AE), the OmniLab Advanced +, System One device (Philips Respironics, Murrysville, PA, U.S.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: MaPGAS Decision Making
Status: NOT_YET_RECRUITING
Conditions: Gender Dysphoria|Gender Dysphoria, Adult|Gender Incongruence|Transgenderism|Transsexualism|Transgender Persons|Phalloplasty
Interventions: BEHAVIORAL: MaPGAS Decision Aid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: An Open-label, Nonrandomized Study to Evaluate the Safety and Immunogenicity of Raxibacumab With Reinjection
Status: COMPLETED
Conditions: Therapeutic Treatment of Inhalation Anthrax
Interventions: BIOLOGICAL: Raxibacumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Nitazoxanide in Hepatic Encephalopathy
Status: UNKNOWN
Conditions: Hepatic Encephalopathy
Interventions: DRUG: Nitazoxanide|DRUG: Oral lactulose|DRUG: Metronidazole|DRUG: Rifaximine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SERIES III RUN-IN Clinical Trial: A Comparison of the Supralimus® Stent With the Xience V™ Stent
Status: TERMINATED
Conditions: Coronary Artery Disease
Interventions: DEVICE: Supralimus(R) Sirolimus-Eluting Coronary Stent System|DEVICE: Xience V™ Everolimus Eluting Coronary Stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Treatment With Mecamylamine in Smoking and Non-smoking Alcohol Dependent Patients
Status: COMPLETED
Conditions: Alcoholism
Interventions: DRUG: mecamylamine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Continuous Local Anesthetic and Steroid Infusion in Abdominal Surgery
Status: COMPLETED
Conditions: Abdominal Pain
Interventions: DRUG: ropivacaine 0.2%|DRUG: Methylprednisolone 1mg/kg|DRUG: saline 0.9%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Acapella VS CHEST Physiotherapy in Post-Operative CABG Patients
Status: COMPLETED
Conditions: CABG
Interventions: OTHER: Base Line + ACEPELLA|OTHER: Base Line + Manual Chest Physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of the Pediatric Formulation of Artemether- Lumefantrine in Children With Uncomplicated P. Falciparum Malaria.
Status: COMPLETED
Conditions: Malaria|Falciparum
Interventions: DRUG: Artemether-lumefantrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Optical Coherence Tomography in Patients With Acute Myocardial Infarction and Nonobstructive Coronary Artery Disease
Status: COMPLETED
Conditions: Myocardial Infarction
Interventions: DEVICE: OCT and CMR imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC