pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Exopulse Mollii Suit, Motor Functions & CP Children With Cerebral Palsy
Status: RECRUITING
Conditions: Cerebral Palsy|Spasticity|Muscle|Pain Syndrome|Hemiplegia|Diplegia|Tetraplegia|Balance
Interventions: DEVICE: Exopulse Mollii Suit|DEVICE: Sham Exopulse Mollii Suit
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Effects and Safety Between Adefovir Dipivoxil Plus Polyene Phosphatidylcholine Versus Adefovir Dipivoxil Alone in Chronic Hepatitis B Patients
Status: UNKNOWN
Conditions: Chronic Hepatitis B
Interventions: DRUG: Adefovir Dipivoxil and polyene phosphatidylcholine|DRUG: Adefovir Dipivoxil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study on Exercise Guided by CPET to Reduce the Risk of Metabolic Cardiovascular Diseases（C-MET Trial）
Status: RECRUITING
Conditions: Metabolic Syndrome
Interventions: BEHAVIORAL: HIIT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Young Melanoma Family Facebook Intervention or Healthy Lifestyle Facebook Intervention in Improving Skin Examination in Participants With Melanoma and Their Families
Status: RECRUITING
Conditions: Clinical Stage 0 Cutaneous Melanoma AJCC v8|Clinical Stage I Cutaneous Melanoma AJCC v8|Clinical Stage IA Cutaneous Melanoma AJCC v8|Clinical Stage IB Cutaneous Melanoma AJCC v8|Clinical Stage II Cutaneous Melanoma AJCC v8|Clinical Stage IIA Cutaneous Melanoma AJCC v8|Clinical Stage IIB Cutaneous Melanoma AJCC v8|Clinical Stage IIC Cutaneous Melanoma AJCC v8|Clinical Stage III Cutaneous Melanoma AJCC v8|First Degree Relative|Pathologic Stage 0 Cutaneous Melanoma AJCC v8|Pathologic Stage I Cutaneous Melanoma AJCC v8|Pathologic Stage IA Cutaneous Melanoma AJCC v8|Pathologic Stage IB Cutaneous Melanoma AJCC v8|Pathologic Stage II Cutaneous Melanoma AJCC v8|Pathologic Stage IIA Cutaneous Melanoma AJCC v8|Pathologic Stage IIB Cutaneous Melanoma AJCC v8|Pathologic Stage IIC Cutaneous Melanoma AJCC v8|Pathologic Stage III Cutaneous Melanoma AJCC v8|Pathologic Stage IIIA Cutaneous Melanoma AJCC v8|Pathologic Stage IIIB Cutaneous Melanoma AJCC v8|Pathologic Stage IIIC Cutaneous Melanoma AJCC v8
Interventions: OTHER: Informational Intervention|OTHER: Informational Intervention|OTHER: Survey Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Improving HIV Care Engagement Among Ugandan Adolescent Girls and Young Women: The Kisoboka Mukwano Intervention
Status: RECRUITING
Conditions: HIV-infection/Aids|Intimate Partner Violence|Domestic Violence|Alcohol Use Disorder
Interventions: BEHAVIORAL: Kisoboka Mukwano ("It is possible, my love!") Intervention|BEHAVIORAL: Screening and Referral
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Fast-track Centre for Hip and Knee Replacement Database
Status: RECRUITING
Conditions: Hip|Knee|Fast-track Surgery|Enhanced Recovery After Surgery|Perioperative Medicine|Ambulatory Surgical Procedures|Perioperative/Postoperative Complications|Patient Satisfaction
Interventions: PROCEDURE: Day-surgery|PROCEDURE: High-risk patient|PROCEDURE: Main Group
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Treatment of Advanced Grade III Periodontal Furcation Lesions
Status: ACTIVE_NOT_RECRUITING
Conditions: Furcation Defects|Periodontitis|Surgical Procedure, Unspecified|Periodontal Bone Loss
Interventions: PROCEDURE: Non-Surgical Periodontal treatment (NSPT)|PROCEDURE: Open Flap Debridement (OFD)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Outcome After Episealer Talus Implant in Treatment of Osteochondral Lesion of the Talus
Status: ACTIVE_NOT_RECRUITING
Conditions: Osteochondral Defect
Interventions: PROCEDURE: Implantation of Episealer Talus Implant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: IPI-145 in Relapsed Refractory Acute Lymphoblastic Leukemia (ALL)
Status: WITHDRAWN
Conditions: Leukemia
Interventions: DRUG: IPI-145|BEHAVIORAL: Follow-up Visit/Call
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Open-label, Randomized, Crossover Study of Comparative Pharmacokinetics and Bioequivalence of Dapagliflozin + Metformin, 10 mg + 1000 mg Versus the Combined Use of Forxiga™, 10 mg and Two Glucophage® Long, ER Tablets, 500 mg Co-administered to Healthy Volunteers Under Standard Fed Conditions
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Xigduo XR|DRUG: Metformin ER (Glucophage® long)|DRUG: Dapagliflozin (Forxiga)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CD19-targeting CAR T Cells in Relapsed or Refractory CD19 Positive B-cell Malignancies
Status: UNKNOWN
Conditions: B-cell Malignancy|B-cell Lymphoma|B-Cell Acute Lymphoblastic Leukaemia
Interventions: BIOLOGICAL: CD19 CAR T
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Efficacy of Stent-balloon-stent (SBS) Technique in the Treatment of Coronary Bifurcation Lesions
Status: RECRUITING
Conditions: Coronary Disease|Heart Diseases|Cardiovascular Diseases|Vascular Diseases|Myocardial Ischemia
Interventions: OTHER: Stent-balloon-stent (SBS) technique
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Fistulotomy With or Without Marsupialization for Treatment of Simple Anal Fistula
Status: COMPLETED
Conditions: Anal Fistula
Interventions: PROCEDURE: Fistulotomy|PROCEDURE: Marsupialization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing Brief Behavioral Therapy (BBT-CI) and Healthy Eating Education Learning (HEAL) for Cancer-Related Sleep Problems While Receiving Chemotherapy
Status: RECRUITING
Conditions: Hematopoietic and Lymphoid Cell Neoplasm|Malignant Solid Neoplasm
Interventions: BEHAVIORAL: Behavioral Intervention|BEHAVIORAL: Behavioral Intervention|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Light Emitting Diodes (LED) Therapy in Rugby Athletes
Status: COMPLETED
Conditions: Phototherapy
Interventions: DEVICE: LED before|DEVICE: LED interval|DEVICE: LED after
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Absnow Absorbable ASD Closure System For Treating ASD Patients
Status: UNKNOWN
Conditions: Heart Septal Defects, Atrial|Atrial Septal Defect
Interventions: DEVICE: Absnow Absorbable ASD Closure System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single Dose Study of SHR4640 in Healthy Subjects
Status: COMPLETED
Conditions: Gout; Hyperuricemia
Interventions: DRUG: SHR4640|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness Trial of Mobile ESI for Toddlers With Autism Identified by Early Screening in Primary Care
Status: RECRUITING
Conditions: Autism Spectrum Disorder
Interventions: BEHAVIORAL: Treatment as Usual|BEHAVIORAL: Early Social Interaction Mobile Coaching (ESI-MC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: This Study in Healthy Men Tests How Itraconazole Influences the Amount of BI 1015550 in the Blood
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BI 1015550|DRUG: itraconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of Jaktinib in the Treatment of Patients With Moderate and Severe Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: Jaktinib|DRUG: Jaktinib|DRUG: Jaktinib|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: a Study of SHR1210 in Combination With Paclitaxel-albumin and Carboplatin in Extensive Stage Small Cell Lung Cancer
Status: UNKNOWN
Conditions: Extensive Stage Small Cell Lung Cancer
Interventions: DRUG: SHR-1210
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: VR Cognitive Rehabiliation for Pediatric TBI
Status: RECRUITING
Conditions: TBI (Traumatic Brain Injury)
Interventions: BEHAVIORAL: Virtual Reality-based Interactive Cognitive Training Program|BEHAVIORAL: Placebo Virtual Reality Game
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Learn About the Effect of Elevit (a Food Supplement Containing Several Vitamins, Minerals, Lutein and DHA) on the Nutrient Content in the Breast Milk and Blood of Women During Breastfeeding Period and on Babies' Physical Growth Parameters
Status: COMPLETED
Conditions: Healthy Lactating Mother
Interventions: DIETARY_SUPPLEMENT: Elevit Breastfeeding & Postnatal Care|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Multicenter Clinical Trial for the Evaluation of Mesenchymal Stem Cells From Adipose Tissue in Patients With Chronic Graft Versus Host Disease.
Status: COMPLETED
Conditions: Graft Versus Host Disease|Chronic and Expanded Graft Versus Host Disease|Immune System Diseases
Interventions: OTHER: Conventional treatment plus intravenous infusion of allogenic mesenchymal stem cells from adipose tissue.|OTHER: Conventional treatment plus intravenous infusion of allogenic mesenchymal stem cells from adipose tissue.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improving Health Outcomes of Migraine Patients Who Present to the Emergency Department
Status: WITHDRAWN
Conditions: Migraine
Interventions: DRUG: Preventative Medication (PM)|BEHAVIORAL: Enhanced Usual Care|BEHAVIORAL: PMR (progressive muscle relaxation therapy)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Zanidatamab (ZW25) With Evorpacept (ALX148) in Patients With Advanced HER2-expressing Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: HER2-expressing Cancers
Interventions: DRUG: Zanidatamab|DRUG: Evorpacept
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cortical Activity and Gait Function for Robotic Gait Training in Hemiparetic Stroke
Status: COMPLETED
Conditions: Stroke
Interventions: DEVICE: Robot-assisted gait training|DEVICE: Treadmill gait training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Heidelberg Engineering SPECTRALIS With OCT Angiography Module
Status: COMPLETED
Conditions: Retinal Vascular|Normal Eyes
Interventions: DEVICE: OCT Angiography|DEVICE: Color Fundus Photography|DEVICE: Fluorescein Angiography|DEVICE: Indocyaine Green Angiography
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Prospective, Phase II Trial Using ctDNA to Initiate Post-operation Boost Therapy After Adjuvant Chemotherapy in TNBC
Status: RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: capecitabine|DRUG: capecitabine + camrelizumab + apatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Neuromuscular Electrical Stimulation (NMES)
Status: COMPLETED
Conditions: Muscle Fiber Atrophy, Type II
Interventions: OTHER: Neuromuscular electrical stimulation|OTHER: voluntary strengthening exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sleep for Health Study on the Effects of Cognitive Behavioral Therapy for Insomnia on Diabetes Risk
Status: RECRUITING
Conditions: Diabetes Mellitus, Type 2|Prediabetic State|Sleep Initiation and Maintenance Disorders
Interventions: OTHER: SHUTi|OTHER: Patient Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Intranasal Morphine for Pain After Elective Orthopedic Surgery
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: DRUG: Intranasal Morphine|DRUG: Placebo|DRUG: IV morphine|DRUG: Placebo|DRUG: Intranasal morphine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility Evaluation of Daily Disposable Toric Soft Contact Lenses Manufactured With an Alternative Hydration Process
Status: COMPLETED
Conditions: Ocular Physiology
Interventions: DEVICE: TEST LENS|DEVICE: CONTROL LENS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Effectiveness of VL-PX10 + VL-P22 Treatment on Pulmonary Fibrosis Secondary to Covid-19
Status: RECRUITING
Conditions: Pulmonary Fibrosis|COVID-19 Respiratory Infection
Interventions: DRUG: VL-PX10 and VL-P22 plus standard care|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bingo Drug-eluting Balloon Versus a Drug-eluting Stent for Coronary Bifurcation Lesions
Status: NOT_YET_RECRUITING
Conditions: Coronary Artery Disease
Interventions: DEVICE: Bingo® Paclitaxel coated balloon|DEVICE: Xience® Alpine Everolimus Eluting Coronary Stent System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized, Controlled Trial of Intranasal Oxytocin as an Adjunct to Behavioral Therapy for Autism Spectrum Disorder
Status: COMPLETED
Conditions: Autism Spectrum Disorders
Interventions: DRUG: Oxytocin|BEHAVIORAL: Social Skills focused CBT|BEHAVIORAL: Stress management/relaxation training|DRUG: placebo drug
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intermittent Fasting Versus Carbohydrate Drinks Before Surgery
Status: RECRUITING
Conditions: Perioperative Care|Intermittent Fasting|Carbohydrate Loading|Preoperative Fasting|Orthopedic Surgery|Insulin Resistance
Interventions: BEHAVIORAL: Time-restricted feeding|DIETARY_SUPPLEMENT: Carbohydrate loading
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Manual Immediately Sequential Bilateral Cataract Surgery (M-ISBCS) vs Refractive Laser-Assisted Immediately Sequential Bilateral Cataract Surgery (ReLA-ISBCS)
Status: UNKNOWN
Conditions: MCS vs ReLACS|Pain Perception Postoperative|Early Anesthesia vs Standard Anesthesia|Immediately Sequential Bilateral Cataract Surgery
Interventions: PROCEDURE: M-IBCS|PROCEDURE: ReLA-IBCS Early|PROCEDURE: ReLA-ISBCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: To Investigate the Effects of Altering the Time of Day of Dosing (Morning or Evening) With Fluticasone Furoate 100 Micrograms Once Daily Administered Via a Dry Powder Inhaler in Subjects With Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Fluticasone Furoate (FF)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Pharmacodynamic Activity of E2730 in Adult Participants With Photosensitive Epilepsy
Status: TERMINATED
Conditions: Photosensitive Epilepsy
Interventions: DRUG: Placebo|DRUG: E2730
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Repurposing Ivermectin for PKDL Treatment
Status: RECRUITING
Conditions: Post-kala-azar Dermal Leishmaniasis
Interventions: DRUG: Ivermectin 6 Mg Oral Tablet|DRUG: Miltefosine Oral Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endoscopic Band Ligation Versus Argon Plasma Coagulation for the Treatment of Gastric Antral Vascular Ectasia: a Randomized Clinical Trial
Status: COMPLETED
Conditions: Gastric Antral Vascular Ectasia
Interventions: DEVICE: Endoscopic Band Ligation|DEVICE: Argon plasma Coagulation (APC) for GAVE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Performance Evaluation of WIRION™ EPD in Patients Undergoing Carotid Artery Stenting
Status: COMPLETED
Conditions: Carotid Artery Diseases|Stroke
Interventions: PROCEDURE: Carotid Artery Stent
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy of an Immunoablative Nonmyeloablative Conditioning Protocol for Autologous Bone Marrow Transplantation (BMT) in Patients With Multiple Sclerosis (MS)
Status: UNKNOWN
Conditions: Multiple Sclerosis
Interventions: PROCEDURE: Autologous bone marrow transplantation|DRUG: Fludarabine|DRUG: Cyclophosphamide|DRUG: Alemtuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Effect of Renal Function on the Single-Dose Pharmacokinetics of BAY 43-9006
Status: COMPLETED
Conditions: Kidney Diseases
Interventions: DRUG: Sorafenib (BAY43-9006, Nexavar)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Intermediate-size Expanded Access Program (EAP), Mesenchymal Stromal Cells (MSC) for Multisystem Inflammatory Syndrome in Children (MIS-C) Associated With Coronavirus Disease (COVID-19)
Status: AVAILABLE
Conditions: Multisystem Inflammatory Syndrome in Children (MIS-C) Associated With Coronavirus Disease (COVID-19)
Interventions: BIOLOGICAL: Remestemcel-L|DRUG: Hydrocortisone|DRUG: Diphenhydramine
Study Type: EXPANDED_ACCESS
Clinical trial: Moroctocog Alfa (AF-CC) for Prophylaxis and Treatment of Bleeding Episodes in Previously Treated Hemophilia A Patients
Status: COMPLETED
Conditions: Hemophilia A
Interventions: BIOLOGICAL: Moroctocog-alfa (AF-CC)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Whole Exome Sequencing in Finding Causative Variants in Germline DNA Samples From Patients With Peripheral Neuropathy Receiving Paclitaxel for Breast Cancer
Status: RECRUITING
Conditions: Breast Carcinoma|Neuropathy
Interventions: OTHER: Laboratory Biomarker Analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical Evaluation of the Safety and Benefits of the Milesman 445 nm Blue Laser on Inflammatory Acne Lesions.
Status: COMPLETED
Conditions: Acne Vulgaris|LASER
Interventions: DEVICE: LASER MILESMAN 445 NM
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nitrous Oxide for Pain Management During In-office Transcervical Sterilization
Status: COMPLETED
Conditions: Contraception|Inhalation of Nitrous Oxide
Interventions: PROCEDURE: In-office Transcervical Sterilization (Essure®)|DRUG: Standard Oral pain medications|DRUG: Intramuscular Ketorolac|DRUG: Placebo pills|OTHER: Oxygen|OTHER: Nitrous Oxide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Empowerment Group Sessions for Treating Suicidal African American Women in Abusive Relationships
Status: RECRUITING
Conditions: Battered Women|Suicide, Attempted
Interventions: BEHAVIORAL: Psychoeducational intervention (PEI)|BEHAVIORAL: Enhanced treatment as usual (ETAU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Once-daily Fixed Combination of Three Antihypertensive Drugs
Status: UNKNOWN
Conditions: Arterial Hypertension
Interventions: DRUG: perindopril, indapamide , amlodipine|DRUG: Tripliam (perindopril, indapamide, amlodipine)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety Study of BIIB033 in Subjects With Multiple Sclerosis
Status: COMPLETED
Conditions: Relapsing-Remitting Multiple Sclerosis|Multiple Sclerosis
Interventions: DRUG: BIIB033|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose:
Clinical trial: Seawater Nasal Wash to Relieve COVID-19 Nasal Symptoms and Reduce SARS-CoV-2 Viral Load.
Status: COMPLETED
Conditions: SARS-CoV2 Infection (COVID-19)|URTI - Viral Upper Respiratory Tract Infection
Interventions: DEVICE: Device: Physiomer undiluted seawater nasal spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Defining Skin Immunity of a Bite of Key Insect Vectors in Humans
Status: COMPLETED
Conditions: Zika|Dengue|Malaria|Chikungunya|Leishmaniasis
Interventions: OTHER: One vector feeding|OTHER: Four vector feeding
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Diabetes Prevention Program (METFIT) in Reducing Insulin Resistance in Stage I-III Breast Cancer Survivors
Status: WITHDRAWN
Conditions: Anatomic Stage I Breast Cancer AJCC v8|Anatomic Stage IA Breast Cancer AJCC v8|Anatomic Stage IB Breast Cancer AJCC v8|Anatomic Stage II Breast Cancer AJCC v8|Anatomic Stage IIA Breast Cancer AJCC v8|Anatomic Stage IIB Breast Cancer AJCC v8|Anatomic Stage III Breast Cancer AJCC v8|Anatomic Stage IIIA Breast Cancer AJCC v8|Anatomic Stage IIIB Breast Cancer AJCC v8|Anatomic Stage IIIC Breast Cancer AJCC v8|Early-Stage Breast Carcinoma|Prognostic Stage I Breast Cancer AJCC v8|Prognostic Stage IA Breast Cancer AJCC v8|Prognostic Stage IB Breast Cancer AJCC v8|Prognostic Stage II Breast Cancer AJCC v8|Prognostic Stage IIA Breast Cancer AJCC v8|Prognostic Stage IIB Breast Cancer AJCC v8|Prognostic Stage III Breast Cancer AJCC v8|Prognostic Stage IIIA Breast Cancer AJCC v8|Prognostic Stage IIIB Breast Cancer AJCC v8|Prognostic Stage IIIC Breast Cancer AJCC v8
Interventions: DIETARY_SUPPLEMENT: Dietary Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: rTMS and Botulinum Toxin in Primary Cervical Dystonia
Status: COMPLETED
Conditions: Primary Cervical Dystonia|Dystonia
Interventions: DEVICE: NeuroStar TMS therapy|DEVICE: Sham NeuroStar TMS therapy|OTHER: Toronto Western Spasmodic Torticollis Rating Scale (TWSTRS)|OTHER: Craniocervical Dystonia Questionnaire (CDQ-24)|OTHER: Cerebellar-brain Inhibition (CBI)|PROCEDURE: Botulinum toxin injections
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Two-Part, Single Ascending Dose Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of DS-7309 in Healthy Volunteers and Subjects With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: DS-7309|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Human Menstrual Blood-derived Mesenchymal Stem Cells Transplantation in Treating Type 1 Diabetic Patients
Status: UNKNOWN
Conditions: Type 1 Diabetes Mellitus
Interventions: BIOLOGICAL: MenSCs transplantation|DRUG: exogenous indulin injection daily
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: the Effect of Minimally Invasive Technique Assisted by Magnetic Resonance Neurography
Status: RECRUITING
Conditions: Orthopedic Surgery
Interventions: PROCEDURE: magnetic resonance neurography|PROCEDURE: no magnetic resonance neurography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Combined PDT and Intravitreal Bevacizumab vs Combination of PDT, Intravitreal Bevacizumab and Triamcinolone for Neovascular AMD
Status: UNKNOWN
Conditions: Neovascular Age-Related Macular Degeneration
Interventions: DRUG: verteporfin, bevacizumab, triamcinolone acetonide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: A Study of rhGAA in Patients With Late-Onset Pompe Disease
Status: COMPLETED
Conditions: Pompe Disease (Late-onset)|Glycogen Storage Disease Type II (GSD-II)|Acid Maltase Deficiency Disease|Glycogenosis 2
Interventions: BIOLOGICAL: Myozyme
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Is There a Transient Rebound Effect of Platelet Reactivity Following Cessation of Dual Antiplatelet Therapy With Ticagrelor - a Single Center Prospective Observational Trial
Status: UNKNOWN
Conditions: Dual Antiplatelet Therapy|Platelet Reactivity
Interventions: OTHER: Platelet reactivity testing
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effects of Pelvic Floor Muscle Training Combined With Otago Exercises in Elderly People With Incontinence
Status: COMPLETED
Conditions: Urinary Incontinence|Pelvic Floor Muscle Weakness|Muscle Weakness
Interventions: OTHER: PFMT|OTHER: PFMT+Otago
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Breathwork for Chronic Musculoskeletal Pain
Status: RECRUITING
Conditions: Pain|Chronic Pain|Pain, Chronic|Musculoskeletal Pain
Interventions: BEHAVIORAL: Guided Resipiration Mindfulness Therapy (GRMT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Tolerance of Sodium Thiosulfate Injection After Ultrasound-guided Percutaneous Irrigation of Calcific Tendinopathy of the Rotator Cuff
Status: COMPLETED
Conditions: Calcific Tendinitis of the Rotator Cuff
Interventions: DRUG: Sodium thiosulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tailored Digital Treatment for Migraine
Status: NOT_YET_RECRUITING
Conditions: Migraine With Aura|Migraine Without Aura
Interventions: BEHAVIORAL: I am (internet approach to migraine)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: CMR Evaluation of Myocardial Inflammation Persistence After Acute Myocarditis: Prognostic Relevance
Status: UNKNOWN
Conditions: Myocarditis Acute|Myocardial Inflammation
Interventions: DIAGNOSTIC_TEST: Cardiac Magnetic Resonance
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of DeTIL-0255 in Adults With Advanced Malignancies
Status: TERMINATED
Conditions: Platinum-resistant Ovarian Cancer|Endometrial Cancer|Cervical Cancer
Interventions: BIOLOGICAL: Drug Product De-TIL-0255
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of 2 Doses of Tiotropium Respimat® Compared to Placebo in Children With Moderate Persistent Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Tiotropium low dose QD|DRUG: Tiotropium high dose QD|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Health Interventions for Survivors and Primary Support Persons of Spinal Cord Injury
Status: COMPLETED
Conditions: Spinal Cord Injuries
Interventions: BEHAVIORAL: Caregiver Only Intervention|BEHAVIORAL: Dual Treatment|BEHAVIORAL: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MK2206 in Treating Patients With Stage I, Stage II, or Stage III Breast Cancer
Status: TERMINATED
Conditions: Estrogen Receptor Negative|Estrogen Receptor Positive|HER2/Neu Negative|HER2/Neu Positive|Progesterone Receptor Negative|Progesterone Receptor Positive|Stage IA Breast Cancer|Stage IB Breast Cancer|Stage IIA Breast Cancer|Stage IIB Breast Cancer|Stage IIIA Breast Cancer|Stage IIIB Breast Cancer|Stage IIIC Breast Cancer|Triple-Negative Breast Carcinoma
Interventions: DRUG: Akt Inhibitor MK2206|PROCEDURE: Therapeutic Conventional Surgery|OTHER: Pharmacological Study|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Paclitaxel and Bevacizumab With or Without Emactuzumab in Treating Patients With Platinum-Resistant Ovarian, Fallopian Tube, or Primary Peritoneal Cancer
Status: TERMINATED
Conditions: Fallopian Tube Adenocarcinoma|Fallopian Tube Clear Cell Adenocarcinoma|Fallopian Tube Endometrioid Adenocarcinoma|Fallopian Tube Mucinous Adenocarcinoma|Fallopian Tube Serous Adenocarcinoma|Fallopian Tube Transitional Cell Carcinoma|Fallopian Tube Undifferentiated Carcinoma|Malignant Ovarian Brenner Tumor|Ovarian Adenocarcinoma|Ovarian Clear Cell Adenocarcinoma|Ovarian Endometrioid Adenocarcinoma|Ovarian Mucinous Adenocarcinoma|Ovarian Seromucinous Carcinoma|Ovarian Serous Adenocarcinoma|Ovarian Transitional Cell Carcinoma|Ovarian Undifferentiated Carcinoma|Primary Peritoneal Serous Adenocarcinoma|Recurrent Fallopian Tube Carcinoma|Recurrent Ovarian Carcinoma|Recurrent Primary Peritoneal Carcinoma
Interventions: BIOLOGICAL: Bevacizumab|BIOLOGICAL: Emactuzumab|OTHER: Laboratory Biomarker Analysis|DRUG: Paclitaxel|OTHER: Pharmacological Study
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Lacosamide as Adjunctive Therapy in Subjects ≥1 Month to <4 Years With Partial-onset Seizures
Status: COMPLETED
Conditions: Epilepsy With Partial-onset Seizures
Interventions: DRUG: Lacosamide|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Pharmacokinetics of Two Generic Antidepressants and Their Respective Brand Preparations
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Venlafaxine|DRUG: Gen-Citalopram|DRUG: Effexor XR|DRUG: Celexa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ٍٍSofosbuvir/Simeprevir/Daclatasvir/Ribavirin and HCV Genotype 4-infected Egyptian Experienced Participants
Status: COMPLETED
Conditions: Chronic Hepatitis C Virus Infection
Interventions: DRUG: SOF/SMV/DCV/RBV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Making Informed Choices on Incorporating Chemoprevention Into Care (MiCHOICE)
Status: RECRUITING
Conditions: Atypical Hyperplasia of the Breast|Lobular Breast Carcinoma In Situ|Pleomorphic Lobular Breast Carcinoma In Situ
Interventions: BEHAVIORAL: Cancer Educational Materials|OTHER: Decision Aid|OTHER: Decision Aid|OTHER: Interview|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Skin-to-skin Contact in Neonatal Intensive Care Unit (NICU), Caregiving Touch and Neural Correlates of Slow Stroking Touch in Preterm Infants
Status: RECRUITING
Conditions: Preterm Birth|Parent-Child Relations
Interventions: DIAGNOSTIC_TEST: Functional Magnetic Risonance Imaging (fMRI) acquisition
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Tofacitinib Hypothesis-generating, Pilot Study for Corticosteroid-Dependent Sarcoidosis
Status: COMPLETED
Conditions: Sarcoidosis, Pulmonary|Sarcoidosis Lung|Sarcoidosis
Interventions: DRUG: Tofacitinib 5mg Oral Tablet [Xeljanz] 16 week trial|DIAGNOSTIC_TEST: Spirometry|GENETIC: RNA Sequencing|DIAGNOSTIC_TEST: Laboratory testing|DRUG: Corticosteroid|DRUG: Tofacitinib 5mg [Xeljanz] 1 year open-label extension
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of JCAR017 in Adult Subjects With Relapsed or Refractory Indolent B-cell Non-Hodgkin Lymphoma (NHL)
Status: ACTIVE_NOT_RECRUITING
Conditions: Lymphoma, Non-Hodgkin
Interventions: DRUG: Fludarabine|DRUG: Cyclophosphamide|DRUG: JCAR017
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Topical Steroids and Cyclosporin-A for COVID-19 Keratoconjunctivitis
Status: UNKNOWN
Conditions: Keratonjunctivitis
Interventions: DRUG: topical steroids and cyclosporin-A
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of Sifalimumab in Adults With Systemic Lupus Erythematosus
Status: COMPLETED
Conditions: Systemic Lupus Erythematosus
Interventions: BIOLOGICAL: Sifalimumab 200 mg|BIOLOGICAL: Sifalimumab 600 mg|BIOLOGICAL: Sifalimumab 1,200 mg|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Direct Versus Indirect Effect of Amino Acids on Hepatokines
Status: NOT_YET_RECRUITING
Conditions: Non-Alcoholic Fatty Liver Disease|Obesity
Interventions: OTHER: Evaluating the acute effect of an amino acid infusion with and without a concomitant infusion of the somatostatin analogue octreotide to eliminate endogenous production of glucagon
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Uric Acid and Hypertension in African Americans
Status: COMPLETED
Conditions: Cardiovascular Diseases|Heart Diseases|Hypertension
Interventions: DRUG: Allopurinol|DRUG: Placebo|DRUG: Chlorthalidone|DRUG: Potassium chloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Incidence, Risk Factors, Severity and Prognosis of Necrotizing Enterocolitis in Turkey
Status: COMPLETED
Conditions: Necrotizing Enterocolitis
Interventions: OTHER: the incidence, risk factors, treatment, prognosis of necrotizing enterocolitis in newborn infants born in newborn intensive care units in our country
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Oxygen-supply on 6-Minute-Walking-Distance of COPD III/IV-patients
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: OTHER: 6MWT with oxygen|OTHER: 6MWT with medical air
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SCREENING
Clinical trial: Association of Midlife Dietary and Lifestyle Factors on Cardiac Functional Changes in the Elderly
Status: UNKNOWN
Conditions: Ageing
Interventions: OTHER: Cardiovascular Magnetic Resonance Imaging (MRI)|OTHER: Echocardiography|OTHER: Tonometry|OTHER: Genetic Testing (Blood)|OTHER: Hand-Grip Strength Measurement|OTHER: Body Fat Mass Analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: PENTA15: Pharmacokinetic Study of Once Versus Twice Daily Abacavir in HIV-1 Infected Children Aged 3 to <36 Months
Status: COMPLETED
Conditions: HIV Infection
Interventions: OTHER: Intervention 1: PK assessment while on Twice Daily Abacavir|OTHER: Intervention 2: PK assessment while on Once Daily Abacavir
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of MG4101 (Allogeneic Natural Killer Cell) for Intermediate-stage of Hepatocellular Carcinoma
Status: COMPLETED
Conditions: Hepatocellular Carcinoma
Interventions: BIOLOGICAL: MG4101
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimal Postoperative Pain Management After Lung Surgery (OPtriAL)
Status: COMPLETED
Conditions: Lung Cancer|Pain, Postoperative|VATS|Locoregional Anaesthesia|Thoracic Epidural
Interventions: PROCEDURE: Thoracic epidural analgesia|PROCEDURE: Continuous regional paravertebral block|PROCEDURE: Single shot intercostal nerve block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Lactobacillus Casei on Respiratory and Gastrointestinal Diseases in Adults
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DIETARY_SUPPLEMENT: Lactobacillus casei Zhang|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Laparoscopic Transversus Abdominis Plane (TAP) Block to Reduce Post-operative Opioids
Status: UNKNOWN
Conditions: Opioid Use
Interventions: DRUG: Bilateral abdominal Lap-TAP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: ENdoluminal LIGHT ActivatED Treatment of Upper Tract Urothelial Cancer (ENLIGHTED) Study
Status: RECRUITING
Conditions: Transitional Cell Cancer of Renal Pelvis and Ureter
Interventions: DRUG: padeliporfin VTP
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare the Effectiveness of Different Anti-HIV Drug Regimens in Keeping Levels of HIV in the Blood as Low as Possible
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Hydroxyurea|DRUG: Efavirenz|DRUG: Stavudine|DRUG: Didanosine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Avelumab in Combination With Hypofractionated Radiotherapy in Patients With Relapsed Refractory Multiple Myeloma
Status: TERMINATED
Conditions: Myeloma, Multiple|Myeloma-Multiple
Interventions: BIOLOGICAL: Avelumab|RADIATION: External beam radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment With Radiolabeled Monoclonal Antibody HuJ591-GS (177Lu-J591) in Patients With Metastatic Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: 177Lu Radiolabeled Monoclonal Antibody HuJ591 (177Lu -J591)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Autologous CAR-T Cells Targeting B7-H3 in PDAC
Status: RECRUITING
Conditions: Pancreas Cancer|Relapse|Resistant Cancer
Interventions: BIOLOGICAL: iC9-CAR.B7-H3 T cell infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sofosbuvir/Pegylated-interferon Plus Ribavirin With HCV Genotype 4
Status: COMPLETED
Conditions: Hepatitis C Virus Infection
Interventions: DRUG: SOF/RBV/PegINFα-2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety Study of Xolair (Omalizumab) in Patients With Chronic Idiopathic Urticaria (CIU) Who Remain Symptomatic Despite Treatment With H1 Antihistamines, H2 Blockers, and/or Leukotriene Receptor Antagonists
Status: COMPLETED
Conditions: Chronic Idiopathic Urticaria
Interventions: DRUG: Omalizumab|DRUG: Placebo|DRUG: H1 antihistamine, H2 antihistamine, leukotriene receptor antagonist|DRUG: Diphenhydramine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Metvix PDT Versus Vehicle PDT With Aktilite CL128 Lamp in Patients With Actinic Keratosis on the Face and Scalp
Status: COMPLETED
Conditions: Actinic Keratosis
Interventions: COMBINATION_PRODUCT: Metvix-PDT|COMBINATION_PRODUCT: Vehicle-PDT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial of a Radiation Sensitizer in Radiochemotherapy for Thoracic Esophageal Squamous Carcinoma
Status: UNKNOWN
Conditions: Esophageal Carcinoma
Interventions: DRUG: placebo|DRUG: Sodium Glycididazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SPECT/CT in Endocrine and Neuroendocrine Tumors
Status: COMPLETED
Conditions: Endocrine and Neuroendocrine Tumors
Interventions: DEVICE: SPECT/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety and Dose Ranging Study of Samalizumab to Treat Relapsing or Refractory CLL or MM
Status: TERMINATED
Conditions: B-cell Chronic Lymphocytic Leukemia|Multiple Myeloma
Interventions: DRUG: Samalizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Microarchitecture, Bone Strength and Fracture Risk in Long-term Type 1 Diabetes
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus
Interventions: DIAGNOSTIC_TEST: Biochemical Tests|DIAGNOSTIC_TEST: Osteodensitometry|DIAGNOSTIC_TEST: Clinical Tests|DIAGNOSTIC_TEST: HR-QCT|DIAGNOSTIC_TEST: HR-pQCT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparing Efficacy and Safety of CinnaGen Beta Erythropoietin (CinnaPoietin®) Versus Eprex® on the Treatment of Anemia in ESRD Hemodialysis Patients
Status: COMPLETED
Conditions: Anemia in End-Stage Renal Disease
Interventions: DRUG: CinnaPoietin®|DRUG: Eprex®|DRUG: Nephrovit|DRUG: Vitamin B12 Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Effectiveness and Safety of Ozanimod in Chinese Adults With Relapsing Multiple Sclerosis
Status: RECRUITING
Conditions: Relapsing Multiple Sclerosis
Interventions: DRUG: BMS-986374
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Empagliflozin as add-on to Insulin in Japanese Patients With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Empagliflozin|DRUG: Placebo|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ketorolac Effects on Post-operative Pain and Bone Healing
Status: TERMINATED
Conditions: Bunion
Interventions: DRUG: Ketorolac|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Palliative Radiotherapy With Lurbinectedin in Patients With Extensive Stage Small Cell Lung Cancer
Status: RECRUITING
Conditions: Extensive Stage Lung Small Cell Carcinoma|Stage IV Lung Cancer AJCC v8
Interventions: DRUG: Lurbinectedin|RADIATION: Palliative Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT