pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Effect of Phosphodiesterase-5 Inhibition With Tadalafil on SystEmic Right VEntricular Size and Function
Status: COMPLETED
Conditions: Heart Defects, Congenital|Transposition of Great Vessels With Ventricular Inversion
Interventions: DRUG: Tadalafil 20 MG|DRUG: Placebo 20 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Structured Exercise Regime in Gestational Diabetes Mellitus
Status: COMPLETED
Conditions: Gestational Diabetes Mellitus
Interventions: OTHER: Structured Exercise for Experimental (Structured Exercise) Group|BEHAVIORAL: Control treatment for both groups
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Immunogenicity of the Hepatitis B Antigen of the GSK Biologicals' Candidate Malaria Vaccine (257049)
Status: COMPLETED
Conditions: Malaria|Malaria Vaccines
Interventions: BIOLOGICAL: GlaxoSmithKline (GSK) Biologicals' candidate Plasmodium falciparum malaria vaccine 257049|BIOLOGICAL: Engerix-B™ vaccine|BIOLOGICAL: Infanrix/Hib™ vaccine|BIOLOGICAL: Polio Sabin™ vaccine|BIOLOGICAL: Rotarix™ vaccine|BIOLOGICAL: Synflorix™ vaccine|BIOLOGICAL: Measles vaccine|BIOLOGICAL: Yellow fever vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of Lasmiditan in Healthy Japanese and Caucasian Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Lasmiditan|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of MDT-10013 in the Treatment of Acute Postoperative Pain Following Bunionectomy
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: MDT-10013|DRUG: Standard of care for pain
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Efficacy and Safety of Intra-articular DA-5202 in Patients With Osteoarthritis of the Knee
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: DRUG: DA-5202 20mg|DRUG: DA-5202 10mg|DRUG: Na Hyaluronate 20mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Home-based Breathing Training on Menopausal Symptoms
Status: COMPLETED
Conditions: Menopause|Menopause Related Conditions
Interventions: BEHAVIORAL: home-based breathing training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I Study of Intrathecal Rituximab in Patients With Lymphomatous Meningitis
Status: WITHDRAWN
Conditions: Lymphoma, B Cell
Interventions: DRUG: intrathecal rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PD-1 Antibody in EBV Positive Metastatic Gastric Cancer Patients.
Status: COMPLETED
Conditions: Gastric Cancer Stage IV|EBV
Interventions: DRUG: PD-1 antibody (SHR-1210)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cognitive Behavioral Sleep Intervention for Prevention of Type 2 Diabetes
Status: SUSPENDED
Conditions: PreDiabetes|Insomnia|Sleep Deprivation
Interventions: BEHAVIORAL: Intensive Lifestyle Intervention|BEHAVIORAL: Intensive Lifestyle Intervention enhanced with Cognitive Behavioral Sleep Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nitric Oxide Inhalation Therapy to Relieve Chest Pain in Patients With Coronary Artery Disease
Status: COMPLETED
Conditions: Coronary Disease|Myocardial Ischemia
Interventions: DRUG: Nitric Oxide and INOpulse Delivery System
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Patient Satisfaction and Tear Osmolarity With the Use of Blink Tears, Blink Gel Tears and Systane Balance
Status: UNKNOWN
Conditions: Dry Eye
Interventions: OTHER: Blink Tears lubricating Eye Drops|OTHER: Blink Gel Tears Lubricating Eye Drops|OTHER: Systane Balance Lubricant Eye Drop
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety And Efficacy Study Of Ziprasidone In Pediatric Psychotic Illness
Status: COMPLETED
Conditions: Schizophrenia|Affective Disorders|Psychotic Disorder|Psychotic Mood Disorder
Interventions: DRUG: Ziprasidone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nevirapine vs. Atazanavir Boosted With Ritonavir on a Background of Truvada in Human Immunodeficiency Virus (HIV) Infected Naive Patients (NEwArT)
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: tenofovir DF 300 mg QD|DRUG: tenofovir DF 300 mg QD|DRUG: emtricitabine 200 mg QD|DRUG: emtricitabine 200 mg QD|DRUG: Nevirapine 200 mg BID|DRUG: Atazanavir 300 mg|DRUG: Ritonavir 100 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: UARK 2014-08 A Phase II Open-Label, Multiple-Dose, Single Agent Study to Evaluate the Overall Response Rate of Orally Administered Trametinib
Status: WITHDRAWN
Conditions: Multiple Myeloma
Interventions: DRUG: Trametinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultravist: Safety and Efficacy in Computed Tomography of Head and Body
Status: COMPLETED
Conditions: Computed Tomography|Diagnostic Imaging
Interventions: DRUG: Iopromide 370 mg I/mL|DRUG: Iopromide 300 mg I/mL
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy and Safety of AIN457 (Secukinumab) in Patients With Relapsing Multiple Sclerosis
Status: TERMINATED
Conditions: Multiple Sclerosis
Interventions: DRUG: Placebo|DRUG: AIN457
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating Behavioral Activation Efficacy in Depressed Spanish-Speaking Latinos
Status: COMPLETED
Conditions: Depression
Interventions: BEHAVIORAL: Behavioral Activation for Depression Treatment|BEHAVIORAL: Supportive Counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Glecaprevir/Pibrentasvir Fixed-dose Combination Treatment for Acute Hepatitis C Virus Infection
Status: COMPLETED
Conditions: Hepatitis C Infection|HIV Infection
Interventions: DRUG: Glecaprevir/Pibrentasvir (G/P)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Hesperidin on Biochemical Factors and Hepatic Fibrosis in Nonalcoholic Fatty Liver Disease
Status: UNKNOWN
Conditions: Non Alcoholic Steatohepatitis
Interventions: DIETARY_SUPPLEMENT: Hesperidin|OTHER: control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I Study to Assess the Pharmacokinetics of Olorofim in Subjects With Hepatic Impairment
Status: COMPLETED
Conditions: Hepatic Impairment
Interventions: DRUG: Olorofim
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Allogeneic Mitochondria (PN-101) Transplantation for Refractory Polymyositis or Dermatomyositis
Status: COMPLETED
Conditions: Polymyositis|Dermatomyositis
Interventions: BIOLOGICAL: PN-101
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Preoperative Duloxetine on Quality of Recovery After Outpatient Laparoscopic Surgery
Status: WITHDRAWN
Conditions: Quality of Recovery|Gynecologic Surgery|Laparoscopy
Interventions: DRUG: duloxetine|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Influence of the Spatial Distribution of Hollow Screws on the Blood Supply and Prognosis of Femoral Neck Fractures
Status: UNKNOWN
Conditions: Femoral Neck Fracture
Interventions: PROCEDURE: Triangular Nail Placement of Femoral Neck
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Does Pantoprazole Reduce the Anti-platelet Effect of Clopidogrel?
Status: COMPLETED
Conditions: Antiplatelet Effect
Interventions: DRUG: Pantoprazole|DRUG: Ranitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Clinical Evaluation of 18F-DOPA Positron Emission Tomography in Medullary Thyroid Cancer
Status: TERMINATED
Conditions: Thyroid Neoplasm|Thyroid Carcinoma|Medullary Carcinoma
Interventions: OTHER: 18F-L-DOPA PET
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Protection Against Visible Light by Dihydroxyacetone in Erythropoietic Protoporphyria
Status: RECRUITING
Conditions: Erythropoietic Protoporphyria
Interventions: OTHER: Dihydroxyacetone|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Gastric Arterial Embolization for Weight Loss
Status: UNKNOWN
Conditions: Obesity
Interventions: PROCEDURE: Embolization of Left Gastric Artery|PROCEDURE: Embolization of Gastroepiploic Artery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Support-t Online Training in Youth Living With Type 1 Diabetes Transitioning to Adult Care
Status: NOT_YET_RECRUITING
Conditions: Diabetes Mellitus|Diabetes Mellitus, Type 1|Glucose Metabolism Disorders (Including Diabetes Mellitus)|Metabolic Disease|Endocrine System Diseases|Autoimmune Diseases|Immune System Diseases
Interventions: OTHER: Support-t
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Ipilimumab and Gemcitabine Hydrochloride in Treating Patients With Stage III-IV or Recurrent Pancreatic Cancer That Cannot Be Removed by Surgery
Status: COMPLETED
Conditions: Duct Cell Adenocarcinoma of the Pancreas|Recurrent Pancreatic Cancer|Stage III Pancreatic Cancer|Stage IV Pancreatic Cancer
Interventions: BIOLOGICAL: ipilimumab|DRUG: gemcitabine hydrochloride|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Prucalopride for the Treatment of Patients With Chronic Constipation
Status: COMPLETED
Conditions: Constipation
Interventions: DRUG: Prucalopride|OTHER: Placebo|DRUG: Prucalopride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The NOR-SWITCH Study
Status: COMPLETED
Conditions: Rheumatoid Arthritis|Spondyloarthritis|Psoriatic Arthritis|Ulcerative Colitis|Crohn's Disease|Psoriasis Chronic
Interventions: DRUG: Innovator infliximab|DRUG: Biosimilar infliximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Diaphragmatic Breathing and Heart Rate Variability Training for Improving Hypertension in Fragile X Associated Tremor/Ataxia
Status: COMPLETED
Conditions: Hypertension|FXTAS
Interventions: DEVICE: HRV and respiratory coherence biofeedback
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Fast Track Rehabilitation in Thoracic Surgery
Status: UNKNOWN
Conditions: Thoracic Surgery
Interventions: BEHAVIORAL: Early exercises|BEHAVIORAL: Removing urinary probe and all catheters.|BEHAVIORAL: Early alimentation|BEHAVIORAL: commun interventions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Controlled Trial of WLS vs. CLI for Severely Obese Adolescents With NASH
Status: COMPLETED
Conditions: Obesity|Nonalcoholic Steatohepatitis|Nonalcoholic Fatty Liver Disease
Interventions: BEHAVIORAL: Comprehensive Lifestyle Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pronator Quadratus Preservation Following Volar Plate Fixation. RCT
Status: UNKNOWN
Conditions: Wrist Fracture,|Distal Radius Fracture|Pronator Quadratus|Volar Plate|Surgery
Interventions: PROCEDURE: Pronator quadratus preservation after volar plate fixation in wrist fractures|PROCEDURE: Pronator quadratus repair after volar plate fixation in wrist fractures|PROCEDURE: Pronator quadratus nonrepair after volar plate fixation in wrist fractures
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Are the Combined Oral Contraceptive Pills Needed for Management of the Simple Ovarian Cysts in Reproductive Women?
Status: UNKNOWN
Conditions: Ovary Cyst
Interventions: DRUG: combined oral contraceptive pills
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Chronic Pain With Cannabidiol (CBD) and Delta-9-tetrahydrocannabinol (THC)
Status: RECRUITING
Conditions: Chronic Pain, Widespread
Interventions: DRUG: Delta-9-Tetrahydrocannabinol|DRUG: Cannabidiol|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Tympanostomy Tubes Versus Eustachian Tube Dilation
Status: WITHDRAWN
Conditions: Eustachian Tube Dysfunction|Eustachian Tube Dysfunction of Left Ear|Eustachian Tube Dysfunction of Right Ear (Diagnosis)|Eustachian Tube Dysfunction of Both Ears (Diagnosis)
Interventions: PROCEDURE: Reducing symptoms of Eustachian tube dysfunction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Phase III Trial of Nilvadipine to Treat Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: Nilvadipine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Pathophysiological Implications of a New Asphyxiation Delaying Device
Status: RECRUITING
Conditions: Avalanche, Landslide, or Mudslide|Asphyxia; Immersion
Interventions: DEVICE: Safeback SBX|DEVICE: Sham device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Exercise Training to Lose Weight in Obese Asthmatics
Status: COMPLETED
Conditions: Asthma|Obesity
Interventions: BEHAVIORAL: Dietary|BEHAVIORAL: Education Program|BEHAVIORAL: Behavioral Therapy|OTHER: Exercise Training|OTHER: Stretching and Breathing exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Maternal Oxygen Administration for Fetal Distress
Status: COMPLETED
Conditions: Oxygen Inhalation Therapy|Second Stage of Labour|Fetal Distress
Interventions: DEVICE: Low flow nasal oxygen|DEVICE: Low flow room air
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study Evaluating the Efficacy and Safety of Giredestrant Plus Everolimus Compared With the Physician's Choice of Endocrine Therapy Plus Everolimus in Participants With Estrogen Receptor-Positive, HER2-Negative, Locally Advanced or Metastatic Breast Cancer (evERA Breast Cancer)
Status: RECRUITING
Conditions: Estrogen Receptor (ER)-Positive, HER2-negative, Locally Advanced or Metastatic Breast Cancer
Interventions: DRUG: Giredestrant|DRUG: Exemestane|DRUG: Fulvestrant|DRUG: Tamoxifen|DRUG: Everolimus|DRUG: LHRH Agonist|DRUG: Dexamethasone Mouth Rinse
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Prospective Observational Study of Adult Strabismus
Status: COMPLETED
Conditions: Convergence Insufficiency|Divergence Insufficiency|Hypertropia
Interventions: DEVICE: Prism|OTHER: Orthoptic Exercises|PROCEDURE: Eye Muscle Surgery|PROCEDURE: Botox Injection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Umbilical Cord Milking in Non-Vigorous Infants
Status: COMPLETED
Conditions: Birth Asphyxia
Interventions: PROCEDURE: Umbilical Cord Milking|PROCEDURE: Early Cord Clamping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: EPA Supplementation on Vascular Inflammation, and Gene Expression of PON2 in Patients With Type II Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus Type II
Interventions: DIETARY_SUPPLEMENT: EPA Supplement|DIETARY_SUPPLEMENT: EPA Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Radiofrequency Ablation vs. Laser Ablation of the Incompetent Small Saphenous Vein
Status: TERMINATED
Conditions: Chronic Venous Insufficiency
Interventions: PROCEDURE: Ablation of the incompetent small saphenous vein
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Stage III or Stage IV Endometrial Cancer
Status: COMPLETED
Conditions: Endometrial Clear Cell Adenocarcinoma|Endometrial Serous Adenocarcinoma|Stage III Uterine Corpus Cancer|Stage IV Uterine Corpus Cancer
Interventions: DRUG: Paclitaxel|DRUG: Cisplatin|RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Influence of an Intervention Program on Altering Health Behavioral Patterns Among IDF's Staff
Status: WITHDRAWN
Conditions: Physical Fitness Habits|Balanced Nutrition|Weight Reduction|Smoking Cessation|Reduction of Stress
Interventions: BEHAVIORAL: Behavioral intervention-to determine the effectiveness of a general intervention on healthy living habits of IDF staff
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Effect of Vitamin D Supplementation on Inflammation and Cardiometabolic Risk Factors in Obese Adolescents
Status: COMPLETED
Conditions: Obesity
Interventions: DRUG: Drisdol (Ergocalciferol) Vitamin D2|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase III Trial Assessing the Pharmacodynamic Effect and the Tolerability of Grazax Treatment
Status: COMPLETED
Conditions: Grass Pollen Allergy
Interventions: DRUG: Grazax|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Quetiapine as an Add on Therapy in the Treatment of Post Traumatic Stress Disorder
Status: COMPLETED
Conditions: Post-Traumatic Stress Disorder
Interventions: DRUG: Quetiapine Fumarate|DRUG: quetiapine fumarate placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intraarterial Infusion Of Erbitux and Bevacizumab For Relapsed/Refractory Intracranial Glioma In Patients Under 22
Status: TERMINATED
Conditions: Glioblastoma Multiforme|Fibrillary Astrocytoma of Brain|Glioma of Brainstem|Anaplastic Astrocytoma|Pilomyxoid Astrocytoma|Mixed Oligodendroglioma-Astrocytoma|Brain Stem Glioma|Diffuse Intrinsic Pontine Glioma
Interventions: DRUG: SIACI of Erbitux and Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Physical Activity Intervention Children With Spastic Diplegia After Resistance Training
Status: UNKNOWN
Conditions: Cerebral Palsy|Spastic Diplegia
Interventions: BEHAVIORAL: Loaded sit-to-stand resistance exercise|BEHAVIORAL: Physical activity intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effect of FertyBiotic Pregnancy in the Metabolic Profile in Pregnant Women
Status: UNKNOWN
Conditions: Pregnancy Related
Interventions: DIETARY_SUPPLEMENT: FertyBiotic Pregnancy|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Compare Effects of Flax Seed Oil, and Fish Oil on Blood Sugar Levels
Status: COMPLETED
Conditions: Polycystic Ovarian Syndrome
Interventions: DIETARY_SUPPLEMENT: Flax Seed Oil|DIETARY_SUPPLEMENT: Fish Oil|DIETARY_SUPPLEMENT: Soybean Oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: PEG Versus PEG+Bisacodyl Versus Sennosides for Colon Cleansing Before Colonoscopy
Status: COMPLETED
Conditions: Colonoscopy Preparation
Interventions: DRUG: polyethylene glycol +Bisacodyl|DRUG: Polyethylene glycol|DRUG: Sennosides
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Five-Drug Anti-HIV Treatment Followed by Treatment Interruption in Patients Who Have Recently Been Infected With HIV
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Ritonavir|DRUG: Abacavir sulfate|DRUG: Amprenavir|DRUG: Lamivudine|DRUG: Stavudine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anti-CD19 CAR T Infusion Combined With Allogeneic Stem Cell Transplantation for B-cell Leukemia/Lymphoma
Status: UNKNOWN
Conditions: B-cell Adult Acute Lymphoblastic Leukemia|B-cell Chronic Lymphocytic Leukemia|Adult Acute Lymphoblastic Leukemia in Remission|Hematopoietic/Lymphoid Cancer|Refractory Chronic Lymphocytic Leukemia
Interventions: BIOLOGICAL: anti-CD19 CAR-T|DRUG: Fludarabine|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Safety of Dupilumab (REGN668/SAR231893) Administered Concomitantly With Topical Corticosteroids (TCS) in Patients With Moderate-to-severe Atopic Dermatitis (AD)
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: Dupilumab|DRUG: Placebo (for Dupilumab)|OTHER: Topical Corticosteroid (TCS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Soluble Corn Fiber and Calcium Utilization in Adolescents
Status: COMPLETED
Conditions: Osteoporosis
Interventions: DIETARY_SUPPLEMENT: No soluble corn fiber|DIETARY_SUPPLEMENT: 12 g soluble corn fiber
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Paclitaxel With or Without Trastuzumab in Treating Patients With or Without HER-2/Neu Breast Cancer That is Inoperable, Recurrent, or Metastatic
Status: COMPLETED
Conditions: HER2-negative Breast Cancer|HER2-positive Breast Cancer|Recurrent Breast Cancer|Stage IIIC Breast Cancer|Stage IV Breast Cancer
Interventions: DRUG: paclitaxel|BIOLOGICAL: trastuzumab|PROCEDURE: quality-of-life assessment|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of 2 Different Resin Based Filling Materials in Posterior Teeth - a Multicenter Study
Status: COMPLETED
Conditions: Caries|Unsatisfactory or Defective Restoration of Tooth
Interventions: DEVICE: Placement of restoration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Liquid-biopsy Informed Platform Trial to Evaluate CDK4/6-inhibitor Resistant ER+/HER2- Metastatic Breast Cancer
Status: RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: RP-6306|DRUG: Gemcitabine|OTHER: Observation|DRUG: Niraparib|DRUG: Fulvestrant
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RCT on Robotic vs. Endo-laparoscopic Approach for Difficult Choledocholithiasis
Status: RECRUITING
Conditions: Choledocholithiasis
Interventions: PROCEDURE: Robotic surgery|PROCEDURE: Endo-laparoscopic surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics and Safety of BILR 355 in Healthy Male Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BILR 355 - Treatment A (current tablet formulation)|DRUG: BILR 355 - Treatment B (new tablet formulation)|DRUG: BILR 355 - Treatment C (new capsule formulation)|DRUG: BILR 355 - Treatment D (current tablet formulation)|DRUG: BILR 355 - Treatment E (new capsule formulation)|DRUG: Ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ATI-502 Topical Solution for the Treatment of Alopecia Areata (AA), Alopecia Universalis (AU) and Alopecia Totalis (AT)
Status: TERMINATED
Conditions: Alopecia Areata|Alopecia Universalis|Alopecia Totalis
Interventions: DRUG: ATI 502 0.46% Topical Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Confirmatory Trial of ETC-1002 in Patients With Hyper-LDL Cholesterolemia
Status: COMPLETED
Conditions: Hyper-low-density Lipoprotein (LDL) Cholesterolemia
Interventions: DRUG: 180mg of ETC-1002(bempedoic acid)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Harmonic™ vs. Electrocautery in Abdominoplasties
Status: COMPLETED
Conditions: Skin and Fat Redundancy and Muscle Diastases
Interventions: DEVICE: Ultrasonic scalpel|DEVICE: monopolar electrosurgery generator and tip
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of PF-08046050 (SGN-CEACAM5C) in Adults With Advanced Solid Tumors
Status: RECRUITING
Conditions: Colorectal Neoplasms|Carcinoma, Non-Small-Cell Lung|Stomach Neoplasms|Pancreatic Ductal Adenocarcinoma|Gastroesophageal Junction Adenocarcinoma|Small Cell Lung Carcinoma
Interventions: DRUG: PF-08046050
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Retapamulin Versus Linezolid in the Treatment of SITL and Impetigo Due to MRSA
Status: COMPLETED
Conditions: Skin Infections, Bacterial
Interventions: DRUG: Retpamulin Ointment, 1%|DRUG: Linezolid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: uPAR PET/CT for Preoperative Staging of Breast Cancer Patients
Status: COMPLETED
Conditions: Breast Cancer
Interventions: OTHER: 68Ga-NOTA-AE105|DEVICE: Positron Emission Tomography PET/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy, Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of ZYIL1 in Patients With Amyotrophic Lateral Sclerosis
Status: ACTIVE_NOT_RECRUITING
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DRUG: ZYIL1 capsules 25 mg and 50 mg Placebo|DRUG: ZYIL1 capsules 50 mg and 25 mg Placebo|DRUG: ZYIL1 capsules 25 mg and ZYIL1 capsules 50 mg|DRUG: Matching placebo 25 mg and Matching placebo 50 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Empirical vs Tailored Therapy for H. Pylori Infection
Status: UNKNOWN
Conditions: Helicobacter Pylori 23S rRNA Clarithromycin Resistance Mutation|Helicobacter Pylori Infection
Interventions: COMBINATION_PRODUCT: triple therapy|COMBINATION_PRODUCT: quadruple therapy|DIAGNOSTIC_TEST: dual-priming oligonucleotide-based multiplex (DPO)-PCR test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Increasing Availability of Lower Energy Meals vs. Menu Energy Labelling on Food Choice
Status: COMPLETED
Conditions: Nutrition Poor|Obesity|Diet, Healthy|Food Selection
Interventions: OTHER: Menu configuration (presence of energy labelling)|OTHER: Menu configuration (more lower energy options added)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Caregiver Wellness After Traumatic Brain Injury (CG-WELL): An Intervention Designed to Promote Well-being in Caregivers of Acute Moderate to Severe Traumatic Brain Injuries
Status: RECRUITING
Conditions: Trauma, Brain
Interventions: BEHAVIORAL: CG-Well|BEHAVIORAL: Information Support & Referral (ISR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study of MOv18 IgE in Folate Receptor Alpha-expressing Platinum Resistant Ovarian Cancer
Status: NOT_YET_RECRUITING
Conditions: Advanced Ovarian Cancer|Platinum-resistant Ovarian Cancer
Interventions: DRUG: MOv18 IgE
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neoantigens Phase I Trial in Newly Diagnosed Glioblastoma Patients
Status: RECRUITING
Conditions: Glioma, Malignant|Antigen-specific Vaccines|Individualized Treatment
Interventions: DRUG: NeoPep Vaccine1 plus Poly-ICLC|DRUG: NeoPep Vaccine2 plus Poly-ICLC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Of Antenatal Maternal Supplementation With GOS/Inulin Prebiotics On Atopic Dermatitis Prevalence In High-Risk One-Year-Old Children
Status: UNKNOWN
Conditions: Dermatitis, Atopic
Interventions: DIETARY_SUPPLEMENT: PREBIOTICS|OTHER: PLACEBO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Phase I Study to Assess the Effect on Healthy Male Volunteers of Ketoconazole on the Pharmacokinetics of a Single Dose of AZD5069 Administered Orally.
Status: COMPLETED
Conditions: Asthma,|Pharmacokinetics,|Cmax,|Tmax,|λz,|AUC,|Ketoconazole,|Metabolite
Interventions: DRUG: AZD5069|DRUG: Ketoconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Rehabilitation of Malnourished Infants With F-100 or Diluted F-100
Status: COMPLETED
Conditions: Severely Malnourished Infants Who Are Less Than 6 Months Old
Interventions: DIETARY_SUPPLEMENT: Infant Formula|DIETARY_SUPPLEMENT: F-100|DIETARY_SUPPLEMENT: Diluted F-100
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Levofloxacin Versus Clarithromycin Triple Therapy in First-Line Treatment for Helicobacter Pylori Eradication
Status: COMPLETED
Conditions: Helicobacter Infections
Interventions: DRUG: Cravit based triple therapy|DRUG: Klaricid based triple therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long-term Iron Supplements and Malaria Risk in Early Pregnancy: a Randomized Controlled Trial
Status: COMPLETED
Conditions: Malaria
Interventions: DIETARY_SUPPLEMENT: Folic Acid|DIETARY_SUPPLEMENT: Folic Acid and Iron
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Prescription Omega-3 Acids on Glucose and Lipoprotein Lipids in Subjects With Hypertriglyceridemia
Status: COMPLETED
Conditions: Hypertriglyceridemia
Interventions: DRUG: POM3|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Misoprostol Vaginal Insert for Induction of Labour
Status: COMPLETED
Conditions: Labor Induction|Cervical Ripening
Interventions: DRUG: Misoprostol vaginal insert 25 mcg|DRUG: Misoprostol vaginal insert 50 mcg|DRUG: Misoprostol vaginal insert 100 mcg|DRUG: Misoprostol vaginal insert 200 mcg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study to Evaluate the Safety and Efficacy of OrienX010 in Unresectable Malignant Melanoma Patients
Status: UNKNOWN
Conditions: Melanoma (Skin)
Interventions: BIOLOGICAL: OrienX010 injection|DRUG: Dacarbazine (DTIC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of BO-112 With Pembrolizumab for Colorectal or Gastric/GEJ Cancer With Liver Metastasis
Status: TERMINATED
Conditions: Colorectal Cancer|Gastric Cancer|Oesophageal Cancer
Interventions: PROCEDURE: Hepatic Biopsy|DRUG: BO-112 with Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility of Transnasal ECHO for Identification of Parapharyngeal Internal Carotid Artery
Status: COMPLETED
Conditions: To Assess Feasibility of the New Application
Interventions: DEVICE: EPIQ 5
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: A Study to Assess the Safety, Reactogenicity and Immunogenicity of a Trivalent Inactivated Poliovirus Vaccine (IPV) Based on Sabin Strains Compared to Conventional Salk IPV in a 6, 10 and 14 Weeks of Age Immunization Schedule
Status: COMPLETED
Conditions: Healthy
Interventions: BIOLOGICAL: sIPV|BIOLOGICAL: cIPV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Growth Hormone (GH) Deficiency & Insulin Like Growth Factor 1 (IGF-I)/ Insulin Like Growth Factor Binding Protein 3 (IGFBP-3) Ratio
Status: COMPLETED
Conditions: Diagnosis of GHD With IGF-I/IGFBP-3 Ratio
Interventions: OTHER: IGF-1/IGFBP-3 ratio
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Photochemical Tissue Bonding
Status: COMPLETED
Conditions: Basal Cell Carcinoma|Squamous Cell Carcinoma|Atypical Nevus
Interventions: PROCEDURE: tissue bonding|PROCEDURE: sutures
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: HDM1002 Tablets in Chinese Overweight and Obese Adult Subjects
Status: NOT_YET_RECRUITING
Conditions: Glucagon-Like Peptide-1 Receptor Agonists
Interventions: DRUG: HDM1002 100 mg QD 12weeks|DRUG: HDM1002 200 mg QD 12weeks|DRUG: HDM1002 400 mg QD 12weeks，Q 2W for titration|DRUG: HDM1002 400 mg QD 12weeks，Q 3W for titration|DEVICE: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study of ONCT-808 in Subjects With Relapsed or Refractory B-Cell Malignancies
Status: RECRUITING
Conditions: Relapsed/Refractory Aggressive B-Cell Malignancies
Interventions: BIOLOGICAL: ONCT-808|DRUG: Bridging Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase III Study of Toripalimab Versus Placebo Plus Chemotherapy in Resectable NSCLC
Status: ACTIVE_NOT_RECRUITING
Conditions: Stage II-III Non-small Cell Lung Cancer
Interventions: DRUG: 4cycles(Toripalimab IV 240mg + platinum-based doublet chemotherapy)+13 cycles(Toripalimab IV 240mg); Biological: Toripalimab|DRUG: 4cycles(Placebo + platinum-based doublet chemotherapy)+13 cycles(Placebo )
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mechanism Study to Investigate Difference in Efficacy of Neoadjuvant Chemoimmunotherapy in Lung Squamous Cell Carcinoma
Status: RECRUITING
Conditions: Tumor Microenvironment|Lung Squamous Cell Carcinoma|Neoadjuvant Chemoimmunotherapy
Interventions: OTHER: Pathological response assessment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: EF5 Compared With Other Methods of Detecting Oxygen Levels in Tumor Cells of Patients With Head and Neck Cancer
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: DRUG: EF5|OTHER: bioluminescence|OTHER: flow cytometry|OTHER: immunohistochemistry staining method|PROCEDURE: biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Generation 100: How Exercise Affects Mortality and Morbidity in the Elderly: A Randomized Control Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Ageing
Interventions: OTHER: Exercise intervention|OTHER: Exercise intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Efficacy of Penile Rehabilitation Using Udenafil After Total Mesorectal Excision of Rectal Cancer
Status: COMPLETED
Conditions: Rectal Cancer
Interventions: DRUG: Placebo drug|DRUG: Udenafil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Problem Adaptation Therapy (PATH) vs. Supportive Therapy in Treating Depressed, Cognitively Impaired Older Adults
Status: COMPLETED
Conditions: Depression
Interventions: BEHAVIORAL: PATH|BEHAVIORAL: ST-CI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of TMS for the Preemptive Treatment of Migraine With Aura
Status: COMPLETED
Conditions: Migraine With Aura
Interventions: DEVICE: Active Transcranial Magnetic Stimulation (TMS) Device|DEVICE: Sham TMS Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Celsi Warmer for the Management of Hypothermic Newborns at the Lagos University Teaching Hospital in Lagos, Nigeria
Status: RECRUITING
Conditions: Neonatal Hypothermia
Interventions: DEVICE: Celsi Warmer
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Perioperative Epidural Block and Dexamethasone in Pancreatic Cancer Surgery
Status: RECRUITING
Conditions: Pancreatic Cancer|Surgery|Epidural Block|Dexamethasone|Overall Survival
Interventions: OTHER: Epidural block|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of LY3537982 in Cancer Patients With a Specific Genetic Mutation (KRAS G12C)
Status: RECRUITING
Conditions: Carcinoma, Non-Small-Cell Lung|Colorectal Neoplasms|Endometrial Neoplasms|Ovarian Neoplasms|Pancreatic Neoplasms|Biliary Tract Neoplasms
Interventions: DRUG: LY3537982|DRUG: Pembrolizumab|DRUG: Cetuximab|DRUG: Pemetrexed|DRUG: Cisplatin|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Microfracture Versus Adipose Derived Stem Cells for the Treatment of Articular Cartilage Defects
Status: RECRUITING
Conditions: Degenerative Lesion of Articular Cartilage of Knee
Interventions: PROCEDURE: ADSC Application|PROCEDURE: Microfracture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of Bi-shRNA-furin and GMCSF Augmented Autologous Tumor Cell Vaccine for Advanced Cancer
Status: COMPLETED
Conditions: Ewings Sarcoma|Non Small Cell Lung Cancer|Liver Cancer
Interventions: BIOLOGICAL: Vigil™|BIOLOGICAL: Vigil™|BIOLOGICAL: Vigil™
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 3 Trial of Pamrevlumab or Placebo in Combination With Systemic Corticosteroids in Participants With Ambulatory DMD
Status: TERMINATED
Conditions: Duchenne Muscular Dystrophy
Interventions: DRUG: Pamrevlumab|DRUG: Placebo|DRUG: Corticosteroids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Predictive Value of the Active Straight Leg Raise on the Efficacy of a SJB in Posterior PGP During Pregnancy
Status: COMPLETED
Conditions: Pelvic Girdle Pain
Interventions: DEVICE: SIJ Belt
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intraoperative Global Longitudinal Strain and Global Longitudinal Strain Rate as Predictors of Unfavorable Outcome in On-Pump Mitral Surgery
Status: COMPLETED
Conditions: Mitral Valve Disease|Low Cardiac Output Syndrome
Interventions: DEVICE: Philips QLAB Ultrasound Quantification Software
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: NOBORI Biolimus-Eluting Versus XIENCE/PROMUS Everolimus-eluting Stent Trial
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DEVICE: Biolimus-eluting stent|DEVICE: Everolimus-eluting stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Collection of Biological Data of Prognostic Relevance in Patients With B-Cell Chronic Lymphocytic Leukemia
Status: UNKNOWN
Conditions: Chronic Lymphocytic Leukemia Stage A(0)|Chronic Lymphocytic Leukemia Stage A(I)|Chronic Lymphocytic Leukemia Stage A(II)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Treatment of Dalpiciclib Combined With Pyrotinib for Trastuzumab-sensitive HER2+ Advanced Breast Cancer(DAP-Her-02)
Status: RECRUITING
Conditions: Breast Neoplasms
Interventions: DRUG: Pyrotinib Maleate|DRUG: Dalpiciclib Isethionate Tablets|DRUG: Inetetamab|DRUG: Fulvestrant
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ponatinib for Chronic Myeloid Leukemia (CML) Evaluation and Ph+ Acute Lymphoblastic Leukemia (ALL)
Status: COMPLETED
Conditions: Chronic Myeloid Leukemia|Ph+ Acute Lymphoblastic Leukemia
Interventions: DRUG: Ponatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High Flow Oxygen With THRIVE Gives Better Oxygenation in Rapid Sequence Induction Patients
Status: UNKNOWN
Conditions: High Flow Oxygen in Rapid Sequence Induction|Airway Morbidity
Interventions: DEVICE: face mask oxygen|DEVICE: High flow oxygen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety and Clinical and Virologic Outcomes in CKD Patients Treated With Nirmatrelvir-ritonavir
Status: COMPLETED
Conditions: COVID-19|Chronic Kidney Disease stage4|Chronc Kidney Disease Stage 5
Interventions: DRUG: Nirmatrelvir/ritonavir
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p