pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Novel Human Milk Based Human Milk Fortifier
Status: ENROLLING_BY_INVITATION
Conditions: Infant, Premature, Diseases
Interventions: DIETARY_SUPPLEMENT: Medolac human milk based human milk fortifier (MHMHMF)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: J-Valve Transfemoral Pivotal Study
Status: NOT_YET_RECRUITING
Conditions: Aortic Valve Regurgitation|Aortic Valve Disease Mixed
Interventions: DEVICE: J-Valve Transfemoral (TF) System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Muscle Function and Strength Training of the Neck and Shoulder in Migraine and Tension-type Headache Patients. A Singel Arm Open Label Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Migraine|Tension-Type Headache|Neck Pain
Interventions: BEHAVIORAL: strength training
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BGB-290 and Temozolomide in Treating Isocitrate Dehydrogenase (IDH)1/2-Mutant Grade I-IV Gliomas
Status: RECRUITING
Conditions: Glioblastoma|IDH1 Gene Mutation|IDH2 Gene Mutation|Low Grade Glioma|Malignant Glioma|Recurrent Glioblastoma|Recurrent WHO Grade II Glioma|Recurrent WHO Grade III Glioma|WHO Grade II Glioma|WHO Grade III Glioma
Interventions: DRUG: PARP Inhibitor BGB-290|DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sequential Paclitaxel Chemotherapy and Radiotherapy as 1st Line Treatment for Elderly Esophageal Squamous Cell Cancer
Status: UNKNOWN
Conditions: Esophageal Squamous Cell Cancer|Elderly Patients
Interventions: OTHER: Sequential chemotherapy （paclitaxel 80mg/m2 d1,d8) and radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Angiotensin Converting Enzyme Inhibition in Infants With Single Ventricle--Pediatric Heart Network
Status: COMPLETED
Conditions: Heart Defects, Congenital|Heart Failure, Congestive
Interventions: DRUG: Enalapril|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ivermectin vs Combined Hydroxychloroquine and Antiretroviral Drugs (ART) Among Asymptomatic COVID-19 Infection
Status: UNKNOWN
Conditions: Asymptomatic Infections|SARS-CoV2 Infection
Interventions: DRUG: Ivermectin Pill|DRUG: Combined ART/hydroxychloroquine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety,Tolerability, and Pharmacokinetic of KPCXM18 for Injection
Status: UNKNOWN
Conditions: Healthy
Interventions: DRUG: KPCXM18|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Colostrum on Gut Permeability and Endotoxin Level in Chronic Alcoholic Disease
Status: UNKNOWN
Conditions: Leaky Gut Syndrome
Interventions: DIETARY_SUPPLEMENT: colostrum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: REVLIMID® (Lenalidomide) for Therapy of Radioiodine-Unresponsive Papillary and Follicular Thyroid Carcinomas
Status: COMPLETED
Conditions: Thyroid Neoplasms
Interventions: DRUG: Lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Determination of the Sensitivity and Specificity of Prick Test Betula Verrucosa
Status: COMPLETED
Conditions: Immune System Diseases
Interventions: BIOLOGICAL: 10 HEP/mL Betula verrucosa allergen extract|BIOLOGICAL: 25 HEP/mL Betula verrucosa allergen extract|BIOLOGICAL: 50 HEP/mL Betula verrucosa allergen extract|BIOLOGICAL: 100 HEP/mL Betula verrucosa allergen extract
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effects of Different Exercise Programs Plus Photobiomodulation on Non-specific Low-back Pain.
Status: COMPLETED
Conditions: Exercise Training|Photobiomodulation Therapy|Low Back Pain
Interventions: OTHER: Pilates training + active PBMT|OTHER: Pilates training + sham PBMT|OTHER: Multicomponent training + active PBMT|OTHER: Multicomponent training + sham PBMT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Establishing a Physical Activity Referral Scheme for People With Noncommunicable Diseases in the German Healthcare System
Status: RECRUITING
Conditions: Non-Communicable Chronic Diseases
Interventions: BEHAVIORAL: Physical activity referral scheme (PARS)|BEHAVIORAL: Physical activity advice (PAA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Postoperative Vitamin Supplementation in Morbidly Obese Patient (VITAAL Study)
Status: COMPLETED
Conditions: Obesity|Vitamin Deficiency
Interventions: DIETARY_SUPPLEMENT: Fit For me|DIETARY_SUPPLEMENT: Davitamon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: To Demonstrate the Relative Bioavailability Study of Ondansetron HCl 24 mg Tablets Under Fasting Conditions
Status: COMPLETED
Conditions: Nausea|Vomiting
Interventions: DRUG: Ondansetron HCl 24 mg Tablets (Sandoz, Inc.)|DRUG: Zofran (Ondansetron HCl) 24 mg Tablets (GlaxoSmithKline)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Nebivolol on Subclinical Left Ventricular dySfunction: A Comparative Study Against Metoprolol
Status: COMPLETED
Conditions: Primary Arterial Hypertension
Interventions: DRUG: Nebilet|DRUG: Corvitol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Different Percentages Body Weight Supported Treadmill Training on Gait, Balance, Quality of Life and Fatigue in Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: BEHAVIORAL: 0% unweighed BWSTT|BEHAVIORAL: 10% unweighed BWSTT|BEHAVIORAL: 20% unweighed BWSTT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Post-market Clinical Study to Evaluate the Safety and Performance of the Carbon Fibre Reinforced Polyetheretherketone Metatarso-Phalangeal (MTP) Plate (CoLink® PCR MTP Plate) for the Treatment of Hallux Rigidus
Status: RECRUITING
Conditions: Hallux Rigidus
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Oxaliplatin, Fludarabine, and Cytarabine in Acute Myeloid Leukemia (AML) or High-Risk Myelodysplastic Syndromes (MDS)
Status: TERMINATED
Conditions: Myelodysplastic Syndromes|Acute Myeloid Leukemia|Leukemia
Interventions: DRUG: Oxaliplatin|DRUG: Fludarabine|DRUG: Cytarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluations of Alcohol Warning Labels
Status: COMPLETED
Conditions: Oral Cancer|Esophageal Cancer|Larynx Cancer|Alcohol Drinking
Interventions: BEHAVIORAL: Narrative pictorial warning labels for alcoholic beverages|BEHAVIORAL: Non-narrative pictorial warning labels for alcoholic beverages
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Quality of Life and Care Needs of Patients With Persistent or Recurrent Ovarian Cancer, Fallopian Tube Cancer, or Peritoneal Cancer
Status: UNKNOWN
Conditions: Anxiety|Fatigue|Nausea and Vomiting|Neurotoxicity Syndrome|Recurrent Fallopian Tube Carcinoma|Recurrent Ovarian Carcinoma|Recurrent Primary Peritoneal Carcinoma|Stage I Ovarian Cancer AJCC v6 and v7|Stage IA Fallopian Tube Cancer AJCC v6 and v7|Stage IB Fallopian Tube Cancer AJCC v6 and v7|Stage IC Fallopian Tube Cancer AJCC v6 and v7|Stage II Ovarian Cancer AJCC v6 and v7|Stage IIA Fallopian Tube Cancer AJCC v6 and v7|Stage IIB Fallopian Tube Cancer AJCC v6 and v7|Stage IIC Fallopian Tube Cancer AJCC v6 and v7|Stage III Ovarian Cancer AJCC v6 and v7|Stage III Primary Peritoneal Cancer AJCC v7|Stage IIIA Fallopian Tube Cancer AJCC v7|Stage IIIB Fallopian Tube Cancer AJCC v7|Stage IIIC Fallopian Tube Cancer AJCC v7|Stage IV Fallopian Tube Cancer AJCC v6 and v7|Stage IV Ovarian Cancer AJCC v6 and v7|Stage IV Primary Peritoneal Cancer AJCC v7
Interventions: PROCEDURE: Assessment of Therapy Complications|OTHER: Medical Chart Review|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Mitoxantrone, Prednisone Plus Sorafenib in Taxane-Refractory Metastatic Hormone Refractory Prostate Cancer (HRPC)
Status: TERMINATED
Conditions: Metastatic Prostate Cancer
Interventions: DRUG: Mitoxantrone|DRUG: Prednisone|DRUG: Sorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics After Oral Administration of AJH-2947 in Healthy Korean and/or Caucasian Adult Male Subjects
Status: RECRUITING
Conditions: Neuropathic Pain|Diabetic Neuropathies|Post Herpetic Neuralgia
Interventions: DRUG: AJH-2947 100 mg (SAD)|DRUG: Placebo|DRUG: AJH-2947 200 mg (SAD)|DRUG: Placebo|DRUG: AJH-2947 300 mg (SAD)|DRUG: Placebo|DRUG: AJH-2947 400 mg (SAD)|DRUG: Placebo|DRUG: AJH-2947 600 mg (SAD)|DRUG: Placebo|DRUG: AJH-2947 800 mg (SAD)|DRUG: Placebo|DRUG: AJH-2947 200 mg (MAD)|DRUG: Placebo|DRUG: AJH-2947 400 mg (MAD)|DRUG: Placebo|DRUG: AJH-2947 600 mg (MAD)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy and Immunotherapy as Treatment for MSS Metastatic Colorectal Cancer With High Immune Infiltrate
Status: RECRUITING
Conditions: Colorectal Cancer Metastatic|High Immune Infiltrate|Microsatellite Stable
Interventions: DRUG: Capecitabine|DRUG: Oxaliplatin|DRUG: Bevacizumab|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Controlled Trial of Internal Fixation Reconstruction With Stent Screw in the Treatment of Kummell's Disease
Status: NOT_YET_RECRUITING
Conditions: BKP|Osteoporotic Vertebral Compression Fracture|Kummell's Disease|Stent-screw-assisted Internal Fixation
Interventions: PROCEDURE: SAIF|PROCEDURE: BKP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Relative Effectiveness of BOLUS Versus Continuous Nasogastric Feeding After Stroke: a Proof of Principal Study
Status: WITHDRAWN
Conditions: Stroke|Dysphagia
Interventions: DIETARY_SUPPLEMENT: bolus NGT feeding|DIETARY_SUPPLEMENT: Continuous NGT feeding|DIAGNOSTIC_TEST: Continuous Glucose Monitoring|DIAGNOSTIC_TEST: Metabolic Profile|RADIATION: Chest X-ray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluation of the Functional Impact of Coronary Stenoses in Diabetics by Spectral CT
Status: NOT_YET_RECRUITING
Conditions: Coronary Stenosis|Diabetic
Interventions: DEVICE: dual-energy dual-layer spectral scanner|DRUG: Stress protocol with adenosin during dual-energy dual-layer spectral scanner
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Post-op T-DM1 in HER-2+ Salivary Gland Carcinomas
Status: RECRUITING
Conditions: Salivary Gland Cancer|HER2 Gene Mutation
Interventions: DRUG: Ado-trastuzumab (T) emtansine (T-DM1)|RADIATION: Standard of Care Radiotherapy|DRUG: Standard of Care Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Ballet Course on Lower Limb Strength, Balance, Working Memory and the Compliance and Satisfaction
Status: RECRUITING
Conditions: Balance|Lower Limb|Strength|Working Memory|Compliance|Satisfaction
Interventions: OTHER: ballet course, strength course
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Lidocaine Improves Satisfaction in Labiaplasty
Status: NOT_YET_RECRUITING
Conditions: Lidocaine
Interventions: DRUG: Lidocaine|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Role of Ascorbic Acid Infusion in Critically Ill Patients With Transfusion Related Acute Lung Injury
Status: COMPLETED
Conditions: Acute Lung Injury, Transfusion Related
Interventions: DRUG: Ascorbic Acid Injectable Product|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Pressure Ulcer Incidence Cat. II+ on a Static Air Mattress: a Multicenter Cohort Study in Nursing Home Residents at Risk
Status: COMPLETED
Conditions: Pressure Ulcer|Pressure Injury|Pressure Sore|Bed Sore
Interventions: DEVICE: CuroCell S.A.M. ® pro mattress
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Neuromodulation of the Fear Extinction Circuit Using Temporally and Anatomically Specific TMS in Humans
Status: RECRUITING
Conditions: PTSD
Interventions: DEVICE: Transcranial magnetic stimulation (TMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: TMC114-TiDP3-C181: Study to Assess the Pharmacokinetics of Darunavir (DRV) With Different Doses of Ritonavir in Healthy Volunteers.
Status: COMPLETED
Conditions: HIV|AIDS
Interventions: DRUG: Darunavir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Cyclobenzaprine Hydrochloride Extended Release for the Treatment of Chronic Migraine
Status: TERMINATED
Conditions: Chronic Migraine
Interventions: DRUG: cyclobenzaprine hydrochloride|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Strengthening Referral Networks for Management of Hypertension Across the Health System (STRENGTHS)
Status: ACTIVE_NOT_RECRUITING
Conditions: Hypertension
Interventions: COMBINATION_PRODUCT: Health IT and Peer Support Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Dried Blood Spot for HCV RNA Testing
Status: COMPLETED
Conditions: Hepatitis C, Chronic
Interventions: DIAGNOSTIC_TEST: Abbott RealTime HCV assay from DBS|DIAGNOSTIC_TEST: HCV for use on the cobas® 6800/8800 Systems from PSC and DBS|DIAGNOSTIC_TEST: Aptima® HCV Quant Dx Assay from DBS|DIAGNOSTIC_TEST: HCV for use on the cobas® 4800Systems from PSC and DBS
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Prospective Phase II Study of Intraoperative Radiotherapy (IORT) in Elderly Patients With Small Breast Cancer
Status: COMPLETED
Conditions: Breast Neoplasms|Breast Diseases|Neoplasm Recurrence, Local|Neoplasms
Interventions: RADIATION: intraoperative radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ceftriaxone as Home IV for Staph Infections
Status: UNKNOWN
Conditions: Staphylococcal Infections|Osteomyelitis|CNS Infection|Septic Arthritis|Diabetic Foot Infection|Vertebral Osteomyelitis|Abscess|Coagulase Negative Staphylococcal Infection
Interventions: DRUG: Ceftriaxone|DRUG: Usual Antibiotics (Cloxacillin, Cefazolin, Daptomycin)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Establishing and Evaluating the Effectiveness of an Augmented Reality Technology in Gender Empowerment System
Status: NOT_YET_RECRUITING
Conditions: Gender|Empowerment|Long Term Care
Interventions: OTHER: AR's platform for gender empowerment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of the Consequences of Infection on Compliance of Modalities of Decisions of Limitations and Stops of Treatments (COVID-19-LAT)
Status: UNKNOWN
Conditions: Patient Hospitalized in Disease Infectious Unit|Patient Hospitalized in Intensive Reanimation Unit|Patient Hopsitalized in Internal Medicine Unit
Interventions: BEHAVIORAL: decisions of limitations and stop processing
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: ACCEL Absorbable Hemostat
Status: RECRUITING
Conditions: Hemostasis
Interventions: DEVICE: ACCEL® Absorbable Hemostat Powder|DEVICE: Gelfoam® (Absorbable Gelatin Sponge, Pfizer Manufacturer Part Number 0342-01)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Propofol 1mg/kg and Propofol 0.5mg/kg for Prevention of Emergence Agitation in Children Undergoing Strabismus Surgery During Sevoflurane Anesthesia
Status: UNKNOWN
Conditions: Strabismus
Interventions: DRUG: Injection of propofol 1.0mg/kg|DRUG: propofol 0.5mg/kg|DRUG: normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of Cetirizine Tablets Versus Ketotifen Dry Syrup in Children With Perennial Allergic Rhinitis
Status: COMPLETED
Conditions: Rhinitis, Allergic, Perennial
Interventions: DRUG: Ketotifen|DRUG: Cetirizine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: PERCEVAL S Valve Clinical Study for Chinese Registration
Status: ACTIVE_NOT_RECRUITING
Conditions: Aortic Valve Disease|Aortic Valve Stenosis
Interventions: DEVICE: Aortic Valve Replacement with Perceval S sutureless heart valve
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of IFN-α2β in the Treatment of Novel Coronavirus Patients
Status: UNKNOWN
Conditions: COVID-19|Recombinant Human Interferon α1β
Interventions: DRUG: Recombinant human interferon α1β
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Surgical Protocol for Peri-implantitis Treatment
Status: UNKNOWN
Conditions: Peri-implantitis
Interventions: PROCEDURE: chlorhexidine|PROCEDURE: Er:YAG laser|PROCEDURE: Air-Powder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mindfulness-based and Compassion-based Interventions in Anxious-Depressive Symptomatology in Mental Health Services
Status: COMPLETED
Conditions: Anxious-Depressive
Interventions: BEHAVIORAL: Mindfulness based Intervention|BEHAVIORAL: Compassion based Intervention|OTHER: TAU
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Imatinib Mesylate With or Without Bevacizumab in Treating Patients With Metastatic or Unresectable Gastrointestinal Stromal Tumor
Status: TERMINATED
Conditions: Gastrointestinal Stromal Tumor
Interventions: BIOLOGICAL: Bevacizumab|DRUG: Imatinib Mesylate|OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacological Study
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Ciclesonide in Pediatric Patients (6 to 11 Years of Age) With Seasonal Allergic Rhinitis (BY9010/M1-417)
Status: COMPLETED
Conditions: Hay Fever|Seasonal Allergic Rhinitis
Interventions: DRUG: Ciclesonide nasal spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Erlotinib Plus Carboplatin and Paclitaxel in Ovarian Carcinoma
Status: COMPLETED
Conditions: Brenner Tumor|Fallopian Tube Cancer|Ovarian Clear Cell Cystadenocarcinoma|Ovarian Endometrioid Adenocarcinoma|Ovarian Mucinous Cystadenocarcinoma|Ovarian Serous Cystadenocarcinoma|Ovarian Undifferentiated Adenocarcinoma|Stage III Ovarian Epithelial Cancer|Stage IV Ovarian Epithelial Cancer
Interventions: DRUG: paclitaxel|DRUG: carboplatin|DRUG: erlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Impact of Text Messaging on Medication Adherence and Exercise Regimen Among Post-myocardial Infarction Patients
Status: COMPLETED
Conditions: Myocardial Infarction
Interventions: BEHAVIORAL: Text message reminder for medication adherence|BEHAVIORAL: Text message reminder for exercise regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Antibiotic Therapy vs Laparscopic Appendectomy in Pediatric Chronic Appendicitis
Status: UNKNOWN
Conditions: Chronic Appendicitis
Interventions: DRUG: Ceftazidime|PROCEDURE: appendectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Real-world Evaluation of Prevalence of Ocular Adverse Events in Patients With Neovascular (Wet) Age-related Macular Degeneration (AMD) Who Received Anti-vascular Endothelial Growth Factor (VEGF) Agents (Komodo Health)
Status: COMPLETED
Conditions: Age-related Macular Degeneration (AMD)
Interventions: OTHER: Aflibercept|OTHER: Ranibizumab|OTHER: Bevacizumab
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Efficacy of a Drink Containing Lupine Protein Hydrolysates on the Immune, Oxidative and Metabolic Status
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DIETARY_SUPPLEMENT: Drink manufactured from lupine peptides
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of Clinical Efficacy of Different Injection Therapies for Treating Humeral Epicondylopathy
Status: UNKNOWN
Conditions: Elbow Tendinopathy
Interventions: PROCEDURE: injection therapy|DRUG: Platelet Rich Plasma|DRUG: Corticosteroid Injection|DRUG: Hyaluronic Acid Injection|OTHER: Placebo Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of External Cold and a Vibrating Device in Reducing Discomfort of Dental Injections in Children
Status: UNKNOWN
Conditions: Pain
Interventions: DEVICE: Buzzy|DRUG: 2%Lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Phase II Pilot Study of Granulocyte Colony-Stimulating Factor for Inherited Bone Marrow Failure Syndromes
Status: COMPLETED
Conditions: Shwachman Syndrome|Fanconi's Anemia|Dyskeratosis Congenita|Thrombocytopenia
Interventions: DRUG: filgrastim
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Longevity of Dental Fillings Utilizing 3D Printing
Status: ENROLLING_BY_INVITATION
Conditions: Dental Restoration Failure of Marginal Integrity|Dental Caries
Interventions: PROCEDURE: Indirect restorations
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Weight-Bearing Exercise on People With Diabetes and Neuropathic Feet
Status: COMPLETED
Conditions: Diabetes Mellitus|Peripheral Neuropathy
Interventions: BEHAVIORAL: weightbearing exercise|BEHAVIORAL: nonweightbearing exercise|BEHAVIORAL: nonexercising control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Combination Chemotherapy With or Without Trastuzumab in Treating Women With Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: BIOLOGICAL: Trastuzumab|DRUG: Cyclophosphamide|DRUG: docetaxel|DRUG: Epirubicin|DRUG: Fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose Escalation and Expansion Study of CPO102, an Anti-claudin 18.2 ADC in Patients With Advanced Cancers
Status: WITHDRAWN
Conditions: Pancreatic Cancer|Gastric Cancer
Interventions: DRUG: CPO102
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I - Pharmacokinetic Comparability Study in Healthy Male Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: MYL-1402O|DRUG: US marketed Avastin(R)|DRUG: EU marketed Avastin(R)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Non-Invasive Ventilation in Amyotrophic Lateral Sclerosis
Status: UNKNOWN
Conditions: Amyotrophic Lateral Sclerosis|Chronic Respiratory Failure
Interventions: DEVICE: Non invasive ventilation delivered with one of the ventilator specifically designed for NIV and given to the patient by the home care providers|DEVICE: Non invasive ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Safety and Efficacy of RVL-1201 in the Treatment of Blepharoptosis
Status: COMPLETED
Conditions: Blepharoptosis
Interventions: DRUG: RVL-1201|OTHER: Vehicle ophthalmic solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: IHT for Mild Cognitive Impairment
Status: RECRUITING
Conditions: Mild Cognitive Impairment|Memory Impairment
Interventions: DEVICE: IHT Treatment|OTHER: Sham-IHT Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ruxolitinib vs Allogeneic SCT for Patients With Myelofibrosis According to Donor Availability
Status: ACTIVE_NOT_RECRUITING
Conditions: Bone Marrow Fibrosis
Interventions: PROCEDURE: Allogeneic stem cell transplantation|DRUG: Ruxolitinib continuous therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cysteamine Compared to Hydroquinone in Melasma
Status: COMPLETED
Conditions: Melasma
Interventions: COMBINATION_PRODUCT: 5% cysteamine cream|COMBINATION_PRODUCT: hydroquinone cream group
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Remineralization Effect of Fluoride Varnishes on Permanent Molars
Status: COMPLETED
Conditions: Remineralization
Interventions: DRUG: Sodium Fluoride|DRUG: Tricalcium Phosphate|DRUG: Xylitol-coated calcium and phosphate|DRUG: Casein phosphopeptide amorphous calcium phosphate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I/II Study of ODX (Osteodex) in Metastatic Castration Resistant Prostate Cancer (CRPC)
Status: COMPLETED
Conditions: Prostate Cancer Metastatic
Interventions: DRUG: Osteodex
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of PDE4 Inhibition With Roflumilast for the Management of Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis Eczema
Interventions: DRUG: ARQ-151 Active|DRUG: ARQ-151 Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Advanced Chronic Myelogenous Leukemia (CML) - Follow On: Study of BMS-354825 in Subjects With CML
Status: COMPLETED
Conditions: Myeloid Leukemia, Chronic, Accelerated Phase|Leukemia, Lymphoblastic, Acute, Philadelphia-Positive
Interventions: DRUG: dasatinib|DRUG: dasatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The START Study Observes Afatinib as First-line Treatment and Sequential Therapy in Patients With Epidermal Growth Factor Receptor (EGFR) Mutation-positive Advanced Nonsmall Cell Lung Cancer
Status: COMPLETED
Conditions: Non-squamous, Non-Small Cell Lung Cancer
Interventions: DRUG: Afatinib
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Before and After Study Studying the Impact of an Analgesia Protocol After Discharge From Outpatient Surgery
Status: COMPLETED
Conditions: Postoperative Pain|Outpatient Surgery
Interventions: COMBINATION_PRODUCT: Measure the impact of the home analgesia protocol on the proportion of patients with a VAS &amp;gt; 3/10 on day one and who did not take analgesics.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Precision Medicine in Ischemic Stroke and Atrial Fibrillation
Status: ACTIVE_NOT_RECRUITING
Conditions: Atrial Fibrillation|Ischemic Stroke
Interventions: OTHER: Atrial fibrillation risk electronic health record alert
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Multiple Dose Comparison of Tiotropium Inhalation Capsules, Salmeterol Inhalation Aerosol and Placebo in Patients With Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Tiotropium (Ba679 BR)|DRUG: Salmeterol|DRUG: Placebo (for Tiotropium )|DRUG: Placebo (for Salmeterol)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: SGT-53, Carboplatin, and Pembrolizumab for the Treatment of Metastatic Triple Negative Inflammatory Breast Cancer
Status: WITHDRAWN
Conditions: Anatomic Stage IV Breast Cancer AJCC v8|Breast Inflammatory Carcinoma|Metastatic Triple-Negative Breast Carcinoma|Prognostic Stage IV Breast Cancer AJCC v8
Interventions: DRUG: Carboplatin|BIOLOGICAL: Pembrolizumab|GENETIC: Transferrin Receptor-Targeted Liposomal p53 cDNA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Health-related Quality of Life After Switching COPD Patients From a Dry Powder Inhaler to a Soft Mist Inhaler Remaining on the Same Inhalative Drug
Status: TERMINATED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DEVICE: Spiriva® Respimat®|DEVICE: Spiriva® HandiHaler®|DRUG: Tiotropium bromide
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Outcome of Resection Anastomosis and Long Term Stenting With Montgomery Tube Operations in Management of Grade 3 Benign Laryngotracheal Stenosis
Status: RECRUITING
Conditions: Grade 3 Benign Laryngotracheal Stenosis
Interventions: PROCEDURE: resection anastomosis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Determine the Effects of Human Growth Hormone and Pioglitazone in Overweight, Prediabetic Adults
Status: COMPLETED
Conditions: Obesity|Metabolic Syndrome|Impaired Glucose Tolerance
Interventions: DRUG: Recombinant human growth hormone; pioglitazone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Procedural Pain Treatment With Transmucosal Sublingual Fentanyl Tablet in Colonoscopy Patients
Status: COMPLETED
Conditions: Colonoscopy|Pain
Interventions: DRUG: Fentanyl|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phase III Study of Trifluridine/Tipiracil With and Without Bevacizumab in Refractory Metastatic Colorectal Cancer Patients
Status: COMPLETED
Conditions: Refractory Metastatic Colorectal Cancer
Interventions: DRUG: Trifluridine/Tipiracil|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Single and Multiple Ascending Dose Study in Healthy Subjects to Assess the Safety, Tolerability, Pharmacokinetics (PK) and Pharmacodynamics (PD) of KP-1199
Status: TERMINATED
Conditions: Analgesia
Interventions: DRUG: KP-1199|DRUG: Placebo oral capsule|DRUG: Oxycodone oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Differences in Speed of Recovery From Anesthesia for Intraoral Surgery
Status: RECRUITING
Conditions: Intraoral Tumor
Interventions: DRUG: Propofol|DRUG: Sevoflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Health enSuite Insomnia: an App-based Treatment for Adult Chronic Insomnia
Status: NOT_YET_RECRUITING
Conditions: Insomnia
Interventions: BEHAVIORAL: Experimental: Health enSuite Insomnia|BEHAVIORAL: Experimental: Health enSuite Insomnia - Deprescribing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SterEotactic AbLative Radiotherapy in PatiEnts With HypertrophiC ObstrucTive Cardiomyopathy
Status: COMPLETED
Conditions: Hypertrophic Obstructive Cardiomyopathy
Interventions: PROCEDURE: stereotactic ablative radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sitagliptin in Non-Diabetic Patients Undergoing General Surgery
Status: COMPLETED
Conditions: Hyperglycemia
Interventions: DRUG: Sitagliptin|DRUG: Placebo|DRUG: Supplemental insulin (insulin lispro)|DRUG: Supplemental insulin (insulin aspart)|DRUG: Long acting basal insulin (insulin detemir)|DRUG: Long acting basal insulin (insulin glargine)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Islet Cell Transplantation in Patients With Type I Diabetes With Previous Kidney Transplantation
Status: COMPLETED
Conditions: Type 1 Diabetes|Organ Transplantation|Immunosuppression
Interventions: PROCEDURE: islet transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Efficacy, Immunogenicity Study of GSK Biologicals' HBV Viral Vector and Adjuvanted Proteins Vaccine (GSK3528869A) in Adult Patients With Chronic Hepatitis B Infection
Status: ACTIVE_NOT_RECRUITING
Conditions: Hepatitis B, Chronic
Interventions: BIOLOGICAL: ChAd155-hIi-HBV low dose formulation|BIOLOGICAL: ChAd155-hIi-HBV high dose formulation|BIOLOGICAL: HBc-HBs/AS01B-4 low dose formulation|BIOLOGICAL: HBc-HBs/AS01B-4 high dose formulation|BIOLOGICAL: MVA-HBV low dose formulation|BIOLOGICAL: MVA-HBV high dose formulation|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Eszopiclone for Improving Sleep in Multiple Sclerosis (MS)
Status: COMPLETED
Conditions: Relapsing Remitting Multiple Sclerosis|Sleep Initiation and Maintenance Disorders|Fatigue
Interventions: DRUG: eszopiclone|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of "My Tools 4 Care" for Family Caregivers of Persons With Dementia
Status: COMPLETED
Conditions: Family|Dementia
Interventions: BEHAVIORAL: My Tools 4 Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Fhytomenadione on Coronary Artery Calcification of Hemodialysis Patients
Status: COMPLETED
Conditions: Coronary Calcification
Interventions: DRUG: phytomenadione|DRUG: placebo solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Edoxaban in Patients With Atrial Fibrillation and Mitral Stenosis
Status: RECRUITING
Conditions: Mitral Valve Stenosis|Atrial Fibrillation|Stroke|Systemic Embolism
Interventions: DRUG: Edoxaban|DRUG: Warfarin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bitter Tastants and Reflux
Status: COMPLETED
Conditions: Gastro Esophageal Reflux
Interventions: DIETARY_SUPPLEMENT: Denatonium Benzoate|DIETARY_SUPPLEMENT: Water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Bioequivalence Study of Modafinil From Bravamax 200 mg Scored Tablets (Chemipharm Pharmaceutical Industries, Egypt) Versus Vigil 200 mg Tablets (Teva GmbH, Germany)
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Bravamax 200 mg (Modafinil)|DRUG: Vigil 200 mg (Modafinil)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Multicenter, Randomized, Open-label, Parallel-group Study to Compare mLSG15 + KW-0761 to mLSG15
Status: COMPLETED
Conditions: Adult T-cell Leukemia-Lymphoma
Interventions: DRUG: VCAP/AMP/VECP(mLSG15)|BIOLOGICAL: KW-0761
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Ofatumumab Treatment on Immune Cells and Meningeal Lymphatic Drainage in Patients With Demyelinating Diseases
Status: RECRUITING
Conditions: Multiple Sclerosis|Neuromyelitis Optica Spectrum Disorder|Demyelinating Diseases of the Central Nervous System
Interventions: DRUG: Ofatumumab
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study To Assess The Effect Of PF-03893787 On Lung Function Following An Allergen Challenge In Asthmatic Subjects
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: PF-03893787|DRUG: Placebo|DRUG: Montelukast
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Safety, Tolerability and Anti-tumour Activity of Ascending Doses of Selumetinib in Combination With MEDI4736 and Selumetinib in Combination With MEDI4736 and Tremelimumab in Patients With Advanced Solid Tumours
Status: COMPLETED
Conditions: Lung Cancer|Melanoma|Head and Neck Carcinoma|Gastroesophageal Cancer|Breast Cancer|Pancreatic Adenocarcinoma|Colorectal Cancer|Biliary Tract Cancer
Interventions: DRUG: Selumetinib|DRUG: MEDI4736|DRUG: Tremelimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Patterns of Activity and Cognition During Treatment (PACT) Study
Status: COMPLETED
Conditions: Breast Neoplasms|Breast Cancer Female
Interventions: BEHAVIORAL: Physical Activity|BEHAVIORAL: Attentional Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE