pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Clinical Study of VG161 in Combination With Nivolumab in Subjects With Advanced Pancreatic Cancer
Status: RECRUITING
Conditions: Advanced Pancreatic Cancer
Interventions: DRUG: Recombinant Human IL12/15-PDL1B Oncolytic HSV-1 Injection (Vero Cell)) in combination with Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Partially Covered and Uncovered Metal Stent for Malignant Distal Biliary Stricture
Status: COMPLETED
Conditions: Malignant Distal Biliary Stricture
Interventions: DEVICE: Deployment of Partially covered biliary self expandable metal stent|DEVICE: Deployment of uncovered biliary self expandable metal stent
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose:
Clinical trial: A Randomized Trial of Effects of Parent Mentors on Insuring Minority Children
Status: COMPLETED
Conditions: Uninsured Children Eligible for Medicaid or CHIP
Interventions: BEHAVIORAL: Parent Mentors
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Experimental Study of the Impact of a Group Therapy Psychological Intervention for Caregivers of Alzheimer's Disease Patients
Status: COMPLETED
Conditions: Psychological Support to Caregivers of Azlheimer's Patients
Interventions: BEHAVIORAL: Cognitive Behavioral Therapy Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy of Periodontal Treatment on Systemic Inflammation and for Prevention of Exacerbations in Patients With COPD
Status: TERMINATED
Conditions: COPD Exacerbation, Periodontal Health
Interventions: PROCEDURE: Periodontal Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Research Study to Look at How Faster Aspart Works in Chinese People With Type 1 Diabetes or Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1|Diabetes Mellitus, Type 2
Interventions: DRUG: Faster Aspart|DRUG: Novo Rapid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Sleep Restriction on BAT Activation in Humans
Status: COMPLETED
Conditions: Sleep Deprivation|Obesity
Interventions: BEHAVIORAL: Partial Sleep Restriction|BEHAVIORAL: Total Sleep Deprivation|BEHAVIORAL: Habitual Sleep
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Acute Effects of Strength Training and High Intensity Training on Functional and Biochemical Measurements of Individuals With Parkinson's Disease in Different Environments and Depths
Status: RECRUITING
Conditions: Parkinson Disease and Hydrotherapy
Interventions: OTHER: Strength training in shallow water and dry land|OTHER: High-intensity training in shallow and deep water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Validating Novel, Non-contrast Cardiac MRI Imaging in Haemodialysis Patients
Status: RECRUITING
Conditions: End Stage Kidney Disease|Fibrosis Myocardial
Interventions: DIAGNOSTIC_TEST: Cardiac MRI scan|DIAGNOSTIC_TEST: Echocardiogram|PROCEDURE: Cardiac explantation|DIAGNOSTIC_TEST: 48-Hour continuous cardiac monitoring|DIAGNOSTIC_TEST: Blood samples
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Investigate Efficacy, Safety, Pharmacodynamics and Pharmacokinetics of ASP6294 in the Treatment of Female Subjects With Bladder Pain Syndrome/Interstitial Cystitis
Status: COMPLETED
Conditions: Bladder Pain Syndrome|Interstitial Cystitis
Interventions: DRUG: ASP6294|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study To Evaluate The Difference In iPad-Based Cognitive Video Game (Akili Interactive's Project: EVO) Performance In Amyloid-Positive Versus Amyloid-Negative Healthy Elderly Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Ritalin|DRUG: Placebo|DRUG: Ritalin|DRUG: Placebo
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Lurasidone HCl: A Phase 3 Study of Patients With Acute Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Lurasidone HCl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy and Stem Cell Transplantation in Treating Children With Central Nervous System Cancer
Status: COMPLETED
Conditions: Brain and Central Nervous System Tumors|Lymphoma|Neuroblastoma|Retinoblastoma
Interventions: BIOLOGICAL: filgrastim|DRUG: carboplatin|DRUG: etoposide|PROCEDURE: bone marrow ablation with stem cell support|PROCEDURE: peripheral blood stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cisplatin, Paclitaxel, and Gemcitabine in Treating Patients With Progressive Unresectable Regional or Metastatic Bladder Cancer
Status: UNKNOWN
Conditions: Bladder Cancer
Interventions: DRUG: cisplatin|DRUG: gemcitabine hydrochloride|DRUG: paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Effect of Equivalent Dose Sufentanil and Afentanil in Bronchoscopic Treatment
Status: RECRUITING
Conditions: Effect of Drug
Interventions: DRUG: Alfentanil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Topically Applied Green Tea Extract for Radio Dermatitis and Radiation Mucositis
Status: UNKNOWN
Conditions: Epigallocatechin Gallate|Radio Dermatitis|Radiation Mucositis
Interventions: DRUG: EGCG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Cardiovascular Magnetic Resonance Prognosticators in Pediatric Oncology Patients With Sepsis
Status: RECRUITING
Conditions: Acute Respiratory Distress Syndrome|Sepsis|Cardiovascular Shock
Interventions: DIAGNOSTIC_TEST: Cardiac MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: ESWT in Lateral Epicondylitis: Clinical,Ultrasonographic Evaluation
Status: COMPLETED
Conditions: Lateral Epicondylitis|Tennis Elbow
Interventions: DEVICE: Extracorporeal Shock Wave Therapy (ESWT)|DEVICE: Sham ESWT|BEHAVIORAL: Resting Splint , Exercises and ice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I/II Study of Radiation Therapy, Paclitaxel Poliglumex and Cetuximab in Advanced Head and Neck Cancer
Status: COMPLETED
Conditions: Carcinoma, Squamous Cell
Interventions: DRUG: paclitaxel poliglumex|BIOLOGICAL: cetuximab|RADIATION: radiation therapy (IMRT or 3D-CRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Efficacy of KAN-JANG® in Mild COVID-19
Status: UNKNOWN
Conditions: Covid19
Interventions: DRUG: Kan Jang capsules|OTHER: Placebo capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cardiovascular Effects of High Intensity Interval Training in Individuals With Paraplegia
Status: COMPLETED
Conditions: Paraplegia, Spinal|Spinal Cord Trauma
Interventions: BEHAVIORAL: High Intensity Interval Training (HIIT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Difluoromethylornithine and High Dose Testosterone With Enzalutamide in Metastatic Castration-Resistant Prostate Cancer
Status: RECRUITING
Conditions: Prostate Cancer
Interventions: DRUG: DFMO|DRUG: testosterone cypionate|DRUG: Luteinizing hormone-releasing hormone (LHRH) analogue|DRUG: Enzalutamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Simultaneous Hyperpolarized [1-13C]Pyruvate and 18F-FDG PET/MRS in Cancer Patients
Status: ENROLLING_BY_INVITATION
Conditions: Breast Cancer|Neuroendocrine Tumors|Neuroendocrine Carcinoma|Neuroendocrine Carcinoma Metastatic|Lymphoma|Sarcoma
Interventions: DRUG: 18F-FDG|DRUG: Injection of hyperpolarized [1-13C]Pyruvate|PROCEDURE: PET/MR/MRS/MRSI scanning
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Role of Dexamethasone for Erector Spinae Plane Block in Patients Undergoing Total Abdominal Hysterectomy
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: bupivacaine|DRUG: dexamethasone|DRUG: placebo to dexamethasone|DRUG: placebo to bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Impact of Vitamin D on Endothelial Function and Blood Biomarkers Including CD28 Null Cells in CKD
Status: COMPLETED
Conditions: CKd Patients With Stage 3 and 4
Interventions: DRUG: Cholecalciferol
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pulsed Electromagnetic Fields (PEMFS) in Complex Regional Pain Syndrome Type i (CRPS-I) of the Foot (PeCFoA)
Status: RECRUITING
Conditions: Pain, Joint|Complex Regional Pain Syndromes|Ankle Disease|Foot Diseases
Interventions: DEVICE: I-One
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Myeloid Derived Suppressor Cells and Chronic Myeloid Leukemia
Status: UNKNOWN
Conditions: Chronic Myeloid Leukemia Patients
Interventions: DIAGNOSTIC_TEST: Measurement level of myeloid derived suppressor cells in CML patients treated with imatinibe 400 mg/day|DIAGNOSTIC_TEST: Measurement level of myeloid derived suppressor cells in CML patients treated with nilotinib 600 mg/day
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nivolumab in Patients With Type B3 Thymoma and Thymic Carcinoma (NIVOTHYM)
Status: ACTIVE_NOT_RECRUITING
Conditions: Thymoma Type B3|Thymic Carcinoma
Interventions: DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Tele-rehabilitation Versus In-clinic Rehabilitation for Upper Limb Motor Function Stroke Patients
Status: RECRUITING
Conditions: Stroke
Interventions: DIAGNOSTIC_TEST: In-clinic Rehabilitation|DIAGNOSTIC_TEST: Tele-rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Analgesia in Minimally Invasive Direct Coronary Artery Bypass Grafting: Programmed Intermittent Bolus Infusions of Erector Spinae Plane Block Versus Paravertebral Block
Status: RECRUITING
Conditions: Regional Anesthesia|Anesthesia, Local|Surgery
Interventions: DRUG: Ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Integrated Neuromuscular Inhibition Technique on Subjects With Neck Pain and Forward Head Posture
Status: UNKNOWN
Conditions: Neck Pain and Forward Head Posture
Interventions: OTHER: Integrated Neuromuscular inhibition|OTHER: traditional treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment Outcomes of MicroPulse Trans-scleral Cyclophotocoagulation in Uncontrolled Glaucoma
Status: COMPLETED
Conditions: Glaucoma|Glaucoma, Open-Angle|Glaucoma, Neovascular|Glaucoma and Ocular Hypertension|Glaucoma Eye|Glaucoma, Uncompensated|Glaucoma Secondary
Interventions: DEVICE: MicroPulse® P3 Glaucoma Device (MP3)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intravenous Iron in paTients With Heart failURe and Reduced Ejection fracTion (HFREF) pLus Iron dEficiency
Status: COMPLETED
Conditions: Heart Failure, Systolic|Iron Deficiency
Interventions: DRUG: Ferric Carboxymaltose|OTHER: blood withdrawal
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Antibiotic Stewardship in AECOPD Through CRP-Guided Management
Status: NOT_YET_RECRUITING
Conditions: Acute Exacerbation of COPD|Lung Diseases|Lung Diseases, Obstructive|Pulmonary Disease, Chronic Obstructive|Respiratory Tract Disease
Interventions: PROCEDURE: The intervention (CRP-guided) group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Dynamic CoROnary RoADmap System for Guidance of Instantaneous Wave-Free Ratio or Fractional Flow Reserve
Status: RECRUITING
Conditions: Ischemic Heart Disease
Interventions: PROCEDURE: roadmap|PROCEDURE: iFR/FFR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Dasatinib in Imatinib Resistant or Intolerant Subjects With Chronic or Advanced Phase CML or Philadelphia Chromosome Positive ALL
Status: WITHDRAWN
Conditions: Chronic Myeloid Leukemia|Acute Lymphoblastic Leukemia
Interventions: DRUG: Dasatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Photobiomodulation in Dry Age Related Macular Degeneration
Status: RECRUITING
Conditions: Age-Related Macular Degeneration
Interventions: DEVICE: Yellow and red light emitting diode photobiomodulation (Eye Light, Espansione Group, Bologna, Italy)|DEVICE: Sham Mask
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Changes in HIV-1 Burden in Peripheral Blood and Lymphoid Tissue Following Zidovudine ( AZT ) Treatment in HIV-1-Infected Patients With CD4+ Cells Between 100 and 500 Cells/mm3.
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Zidovudine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Video System in Improving Learning of Tracheal Intubation Using Standard Laryngoscopy Among Novices
Status: COMPLETED
Conditions: Intubation Intraesophageal
Interventions: DEVICE: Airtraq|OTHER: Control group, taught with a standard Macintosh laryngoscope
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Safety and Efficacy Study of Stem Cell Transplantation to Treat Dilated Cardiomyopathy
Status: COMPLETED
Conditions: Dilated Cardiomyopathy
Interventions: BIOLOGICAL: CD34+ autologous stem cell transplantation|DRUG: Bone Marrow Stimulation|BIOLOGICAL: SC therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Eribulin Mesylate in Treating Patients With Advanced or Recurrent Cervical Cancer
Status: COMPLETED
Conditions: Recurrent Cervical Cancer|Stage IIIA Cervical Cancer|Stage IIIB Cervical Cancer|Stage IVA Cervical Cancer|Stage IVB Cervical Cancer
Interventions: DRUG: eribulin mesylate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PS-341 Plus Carboplatin in Platinum and Taxane Resistant Recurrent Ovarian Cancer, Primary Peritoneal Cancer, and Fallopian Tube Cancer
Status: COMPLETED
Conditions: Ovarian Cancer|Primary Peritoneal Cancer|Fallopian Tube Cancer
Interventions: DRUG: PS-341 (Bortezomib)|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TACE and Adefovir Compared With Transarterial Chemoembolization (TACE) Alone for Hepatitis B Virus (HBV)-Related Unresectable Hepatocellular Carcinoma (HCC)
Status: UNKNOWN
Conditions: Hepatitis B Virus|Hepatocellular Carcinoma
Interventions: DRUG: adefovir|PROCEDURE: TACE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Detecting Diabetes Sooner With a Risk Survey for the Family Doctor:Comparing Internet and Traditional Methods of Communication for Patients and Doctors
Status: UNKNOWN
Conditions: Diabetes
Interventions: OTHER: CANRISK (Canadian Diabetes Association Assessment)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Off Axis View Radiographs Assessing Hallux Valgus Interphalangeus in Hallux Valgus Deformity
Status: COMPLETED
Conditions: Hallux Valgus Interphalangeus|Hallux Valgus
Interventions: DIAGNOSTIC_TEST: assessment of standardized and off axis view radiographs
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Propranolol Versus Propranolol and Clonidine in Sympathetic Hyperactivity After Moderate Traumatic Brain Injury
Status: UNKNOWN
Conditions: Traumatic Brain Injury
Interventions: DRUG: Propranolol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: DIAGNOSTIC
Clinical trial: Fusion Guided Thermal Ablation Combined With External Beam Radiation for Hepatic Neoplasms
Status: TERMINATED
Conditions: Liver Neoplasms|Hepatic Cancer|Liver Cancer
Interventions: PROCEDURE: Thermal Ablation|PROCEDURE: Standard External Beam Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adjuvant Cetuximab and Chemoradiotherapy Using Either Cisplatin or Docetaxel in Treating Patients With Resected Stage III or Stage IV Squamous Cell Carcinoma or Lymphoepithelioma of the Head and Neck
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: BIOLOGICAL: cetuximab|DRUG: cisplatin|DRUG: docetaxel|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EXHIT ENTRE Comparative Effectiveness Trial
Status: RECRUITING
Conditions: Substance Use Disorder|Opioid Use Disorder, Moderate|Opioid Use Disorder, Severe
Interventions: DRUG: Extended Release Buprenorphine|DRUG: Treatment as Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Little Cigar and Cigarillo Warnings to Reduce Tobacco-Related Cancers and Disease - Eye Tracking
Status: NOT_YET_RECRUITING
Conditions: Tobacco Use
Interventions: BEHAVIORAL: pictorial warning and no flavor|BEHAVIORAL: pictorial warning and 'sweet' flavor|BEHAVIORAL: text-only warning and no flavor|BEHAVIORAL: text-only warning and 'sweet' flavor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study in Healthy Adult Subjects to Evaluate the Safety, Tolerability, and Pharmacokinetic Profiles of Multiple Doses of ABT-072 Used to Treat Hepatitis C
Status: COMPLETED
Conditions: HCV Infection
Interventions: DRUG: ABT-072|OTHER: ketoconazole|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Hydralazine Valproate for Cervical Cancer
Status: UNKNOWN
Conditions: Metastatic Cervical Cancer
Interventions: DRUG: Hydralazine and magnesium valproate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of HCP1102 Capsule in Patients With Perennial Allergic Rhinitis
Status: COMPLETED
Conditions: Perennial Allergic Rhinitis
Interventions: DRUG: HCP1102|DRUG: HGP1408
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Outcome of High Dose Vitamin D on Prognosis of Sepsis Requiring Mechanical Ventilation
Status: COMPLETED
Conditions: Sepsis
Interventions: DRUG: Vitamin D3 tablets|DRUG: Vitamin D tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Balance Training With Stroboscopic Vision
Status: COMPLETED
Conditions: Ankle Inversion Sprain|Proprioceptive Disorders
Interventions: OTHER: Neuromuscular training|OTHER: Stroboscopic glasses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CPVI Alone Versus CPVI Plus Low-Voltage Areas Ablation During SR Versus CPVI Plus Low-Voltage Areas Ablation During AF for the Treatment of CAF
Status: NOT_YET_RECRUITING
Conditions: Atrial Fibrillation
Interventions: PROCEDURE: STABLE-SR|PROCEDURE: STABLE-AF|PROCEDURE: CPVI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Diagnostic Performance and Safety of 18F-NaF-PET/CT in Bone Metastases Compared With 99mTc⁃MDP-BS±SPECT
Status: COMPLETED
Conditions: Bone Metastases
Interventions: DRUG: Sodium Fluoride F-18 Injection|DRUG: Technetium[99mTc] Methylenediphosphonate Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of Enbrel in Rheumatoid Arthritis (RA) Subjects With Comorbid Disorders
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Enbrel|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: T-cell Depleted Bone Marrow and G-CSF Stimulated Peripheral Stem Cell Transplantation From Related Donors in Treating Patients With Leukemia, Lymphoblastic Lymphoma, Myelodysplastic Syndrome, or Aplastic Anemia
Status: COMPLETED
Conditions: Leukemia|Lymphoma|Myelodysplastic Syndromes|Myelodysplastic/Myeloproliferative Neoplasms
Interventions: BIOLOGICAL: anti-thymocyte globulin|BIOLOGICAL: filgrastim|DRUG: cyclophosphamide|DRUG: cytarabine|DRUG: methylprednisolone|DRUG: thiotepa|PROCEDURE: in vitro-treated bone marrow transplantation|PROCEDURE: in vitro-treated peripheral blood stem cell transplantation|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preoperative Evaluation of Lymph Nodes of Cholangiocarcinoma
Status: RECRUITING
Conditions: Hilar Cholangiocarcinoma|Intrahepatic Cholangiocarcinoma|Common Bile Duct Neoplasms|Cholangiocarcinoma|Adenocarcinoma
Interventions: PROCEDURE: Endoscopic Ultrasound registration
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Applying Flipped Learning Concepts to Simulation: the Effect on the Retention of Non-technical Skills
Status: COMPLETED
Conditions: Crisis Resource Management|Flipped Classroom
Interventions: OTHER: Preparatory instructional videos (flipped classroom model)|OTHER: Sham video
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Washed Microbiota Transplantation (WMT) for Chronic Kidney Disease (CKD)
Status: RECRUITING
Conditions: CKD
Interventions: DRUG: Fecal Microbiota Transplantation|OTHER: Standard of Care for Chronic Kidney Disease
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testing the Addition of Darolutamide to Hormonal Therapy (Androgen Deprivation Therapy [ADT]) After Surgery for Men With High-Risk Prostate Cancer, The ERADICATE Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Carcinoma
Interventions: DRUG: Darolutamide|DRUG: Goserelin Acetate|DRUG: Leuprolide Acetate|DRUG: Placebo Administration|OTHER: Quality-of-Life Assessment|DRUG: Triptorelin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Xiaxi Program for Back Health
Status: ACTIVE_NOT_RECRUITING
Conditions: Adults|No Sagittal Spine Disposition Disorder|No Surgery on the Spine or the Hamstring|No Specific Treatment for Spinal Pathology|Not Involved in Structured Exercise Programs Before or During the Time of the Study
Interventions: BEHAVIORAL: Xiaxi intervention program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Mediastinal Lymph Node Dissection in Conjunction With Pulmonary Metastasectomy From Colorectal Cancer
Status: UNKNOWN
Conditions: Lung Neoplasms|Neoplasm Metastasis|Colorectal Cancer
Interventions: PROCEDURE: Total mediastinal lymph node dissection and pulmonary metastasectomy|PROCEDURE: Only pulmonary metastasectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Assessing the Efficacy and Safety of Alpelisib Plus Fulvestrant in Men and Postmenopausal Women With Advanced Breast Cancer Which Progressed on or After Aromatase Inhibitor Treatment.
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Fulvestrant|DRUG: Alpelisib|DRUG: Alpelisib placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of IVC Filter Retrieval With the Günther Tulip Vena Cava Filter
Status: COMPLETED
Conditions: Pulmonary Embolism|Venous Thromboembolism
Interventions: DEVICE: Günther Tulip Vena Cava Filter
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Mobile Application for Bariatric Surgery Patients
Status: RECRUITING
Conditions: Obesity|Bariatric Surgery|Quality of Life|Complication|Mobile Health|eHealth|Self Management
Interventions: OTHER: e-BariS app group|OTHER: Self-Monitoring Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Metastatic Solid Cancer Clinical Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Cancer
Interventions: DRUG: Keytruda Injectable Product|DRUG: Yervoy Injectable Product|DRUG: GM-CSF|PROCEDURE: Non-ablative Cryosurgical freezing
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study on the Neoadjuvant Use of Chemotherapy and Celecoxib Therapy in Patients With Invasive Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: celecoxib and chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of a Tetravalent Dengue Vaccine Administered Concomitantly or Sequentially With Adacel® in Healthy Subjects
Status: TERMINATED
Conditions: Dengue Fever|Dengue Hemorrhagic Fever
Interventions: BIOLOGICAL: CYD Dengue Vaccine|BIOLOGICAL: Tdap: Tetanus Toxoid, Reduced Diphtheria Toxoid and Acellular Pertussis Vaccine adsorbed|BIOLOGICAL: Tdap: Tetanus toxoid, reduced diphtheria toxoid and acellular pertussis vaccine adsorbed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of the Safety of KSP Heptapeptide (KSP-910638G)
Status: COMPLETED
Conditions: Healthy Adults
Interventions: DRUG: KSP-910638G, 0.4 mg|DRUG: KSP-910638G, 1.2 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Effect of Acupressure on Acute Pain, Stress and Satisfaction During Venipuncture
Status: UNKNOWN
Conditions: Pain, Acute|Satisfaction, Patient|Stress
Interventions: OTHER: Acupressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: ModificatiOn and Treatment of stenoseD Calcified inFrainguinal Lesions With Laser atherectomY in a Pilot Study
Status: COMPLETED
Conditions: Peripheral Arterial Disease
Interventions: DEVICE: Laser induced pressure wave calcium modification
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Intermittent Hypoxia in Healthy Individuals
Status: ENROLLING_BY_INVITATION
Conditions: Healthy
Interventions: OTHER: Acute Intermittent Hypoxia|OTHER: Sham Acute Intermittent Hypoxia
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Sarcopenia and Risk of Falls in Patients With Major Chronic Diseases
Status: COMPLETED
Conditions: Stroke|Osteoporosis|Chronic Kidney Diseases|Cancer
Interventions: BEHAVIORAL: elastic band strengthening exercise|DIETARY_SUPPLEMENT: diet counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: CAPTAIN-AD: Clinical Study of AmorePacific's TRPV1 Antagonist in Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: PAC-14028 cream 1.0%|DRUG: PAC-14028 cream Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intrapleural Catheter Daily Versus Three Times a Week Drainage
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Cancer|Pleural Effusion
Interventions: PROCEDURE: Intrapleural catheter (IPC) drained|PROCEDURE: IPC Placement|RADIATION: Chest X-Ray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Rimonabant as an Aid to Smoking Cessation With or Without Nicotine Patch
Status: COMPLETED
Conditions: Smoking Cessation
Interventions: DRUG: rimonabant (SR141716)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study in Subjects Undergoing Complete Abdominoplasty
Status: COMPLETED
Conditions: Postsurgical Pain
Interventions: DRUG: CA-008 5 mg|DRUG: Placebo|DRUG: Bupivacaine Hydrochloride|DRUG: Hydromorphone|DRUG: Fentanyl|DRUG: Acetaminophen|DRUG: Oxycodone|DRUG: CA-008 10 mg|DRUG: CA-008 15 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Shock and Acute Conditions OutcOmes Platform
Status: ACTIVE_NOT_RECRUITING
Conditions: Circulatory Shock|Sepsis|Cardiogenic Shock|Major Trauma|Surgical Shock
Interventions: DRUG: Inotrope|DEVICE: Mechanical circulatory support|DRUG: anti-bodies
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Randomized Clinical Trial Assessing Laryngeal Mask Airway Versus Face-mask Ventilation in Neonatal Resuscitation
Status: COMPLETED
Conditions: Asphyxia Neonatorum
Interventions: DEVICE: Laryngeal Mask Airway|DEVICE: Face mask ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multiple Oral Doses Of PH-797804 In Healthy Japanese Adult Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: 1 mg|DRUG: 5 mg|DRUG: 10 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pediatric Asthma Alert Intervention for Minority Children With Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: BEHAVIORAL: Pediatric Asthma Alert (PAAL)|BEHAVIORAL: Standard asthma education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: The Optimal Mode of Renal Replacement Therapy in Acute Kidney Injury (OMAKI) Study
Status: COMPLETED
Conditions: Acute Kidney Injury
Interventions: DEVICE: Continuous venvenous hemofiltration (CVVH)|DEVICE: Continuous venovenous hemodialysis (CVVHD)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: De-escalated Cyclophosphamide (PTCy) and Ruxolitinib for Graft-versus-Host Disease (GVHD) Prophylaxis
Status: RECRUITING
Conditions: Graft-versus-host Disease
Interventions: DRUG: Cyclophosphamide|DRUG: Tacrolimus|DRUG: Mycophenolate Mofetil|DRUG: Ruxolitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cardiac Amyloidosis Prevalence and Outcome in Aortic Stenosis Patients Undergoing Transcatheter Aortic Valve Implantation
Status: UNKNOWN
Conditions: Aortic Stenosis
Interventions: RADIATION: HDP-Tc99m bone scintigraphy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Prospective, Randomized Clinical Trial of PRP Concepts Fibrin Bio-Matrix in Chronic Non-Healing Venous Leg Ulcers
Status: UNKNOWN
Conditions: Venous Leg Ulcers
Interventions: DEVICE: PRP Concepts Fibrin Bio-Matrix|OTHER: Usual and Customary Practice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Teachable Moment to Opt-out of Tobacco: Interactive Voice Response Quit Line for Veteran Active Smokers With Lung Nodules
Status: ENROLLING_BY_INVITATION
Conditions: Solitary Pulmonary Nodule|Multiple Pulmonary Nodules|Tobacco Use
Interventions: BEHAVIORAL: TeaM OUT Intervention|BEHAVIORAL: Enhanced Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Randomized-Control Study of Gym Tonic's Community Based Strength Training Intervention.
Status: COMPLETED
Conditions: Frailty|Muscle Loss|Sarcopenia
Interventions: DEVICE: Gym Tonic programme and Gym equipment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Phase I/II for Safety and Efficacy of Nilotinib in a Population Steroid-refractory/or Steroid-dependent cGVHD
Status: COMPLETED
Conditions: Chronic Graft Versus Host Disease
Interventions: DRUG: nilotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Characteristics, Safety, Tolerability and Immunogenicity of LY01008 and Avastin in Healthy Chinese Male Subjects
Status: COMPLETED
Conditions: Metastatic Colorectal Cancer|Non Small Cell Lung Cancer Metastatic|Non Small Cell Lung Cancer Recurrent
Interventions: DRUG: LY01008|DRUG: Avastin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of GW685698X for the Treatment Of Perennial Allergic Rhinitis in Adolescents and Adults
Status: COMPLETED
Conditions: Rhinitis, Allergic, Perennial
Interventions: DRUG: GW685698X aqueous nasal spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Breast-Dedicated PET Camera With 1 Millimeter Spatial Resolution
Status: NOT_YET_RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: 18F-FDG|DEVICE: Breast-dedicated PET camera
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Three Types of Nucleotide/Nucleoside Analogues Treatment in HBV Related ACLF
Status: UNKNOWN
Conditions: Hepatitis B|Acute-On-Chronic Liver Failure
Interventions: DRUG: Entecavir|DRUG: Tenofovir Disoproxil Fumarate|DRUG: Tenofovir Alafenamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of the Administration of a Symbiotic (E. Faecium and Agave Inulin) on Mild Cognitive Impairment in Older Adults
Status: RECRUITING
Conditions: Cognitive Impairment
Interventions: DIETARY_SUPPLEMENT: Enteroccocus Facieum and Agave Inulin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Point-of-Care RBC Washing to Prevent Transfusion-Related Pulmonary Complications
Status: COMPLETED
Conditions: Blood Transfusion Complications
Interventions: BIOLOGICAL: Point-of-care washed red blood cell transfusion.|BIOLOGICAL: Standard of care red blood cell transfusion.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Improving PRO for Patients With Cancer Using ECAs and Data Visualization
Status: NOT_YET_RECRUITING
Conditions: Cancer
Interventions: BEHAVIORAL: Embodied Conversational Agent|BEHAVIORAL: REDCap Survey
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of the Therapeutic Effect of Platelet Rich Plasma (PRP) in Periorbital Hyperpigmentation(POH)
Status: UNKNOWN
Conditions: Periorbital Hypermelanosis
Interventions: OTHER: PRP
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Herbal Treatment to Improve Chemotherapy Delivery
Status: UNKNOWN
Conditions: Colon Cancer
Interventions: DRUG: Tonifying Spleen and Kidney Sequential Regimen|DRUG: Placebo of 'Tonifying Spleen and Kidney Sequential Regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of PRCL-02 in Healthy Volunteers and Plaque Psoriasis
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: PRCL-02|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Personalized Therapies in Inflammatory Complex Disease
Status: RECRUITING
Conditions: Inflammatory Disease|Autoimmune Diseases
Interventions: DRUG: Kineret|DRUG: Humira|DRUG: Stelara|DRUG: Cosentyx|DRUG: Roactemra|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Evaluation of the Effect of Food on the PK of a Novel PanCytoVir™ Suspension (100mg/ml), in Healthy, Adult Volunteers
Status: NOT_YET_RECRUITING
Conditions: Relative Bioavailability
Interventions: DRUG: PanCytoVir™
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comprehensive Imaging of Perforator Vessels and Subcutaneous Vascular Network With No-Exogenous Contrast and Non-Ionizing-Radiation Magnetic Resonance Angiography
Status: ACTIVE_NOT_RECRUITING
Conditions: Perforator Flap Surgery
Interventions: DEVICE: MRI Scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of the PİKSEÇ App on Peripheral Intravenous Catheter Insertion on Success, Pain and Emotional Level in Children
Status: RECRUITING
Conditions: Nurse's Role|Peripheral Venous Catheterization|Pain|Emotional Stress
Interventions: OTHER: PİKSEÇ|OTHER: Routine care
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Feasibility and Efficacy Study of the CardioPulmonary Monitoring (CPM) System in Patients With Chronic Heart Failure
Status: RECRUITING
Conditions: Heart Failure
Interventions: DEVICE: CPM Device + Monitoring|DRUG: CPM Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Radiofrequency Ablation for Gastric Metaplasia and Dysplasia
Status: COMPLETED
Conditions: Gastric Dysplasia|Intestinal Metaplasia
Interventions: DEVICE: Endoscopic radiofrequency ablation catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Allogeneic Mesenchymal Stem Cells for the Survivors of Ischemic Stroke Trial (ASSIST)
Status: UNKNOWN
Conditions: Ischemic Stroke
Interventions: DRUG: it-hMSC|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of Sustained Heat Treatment on Delayed-Onset Muscle Soreness (DOMS)
Status: COMPLETED
Conditions: Delayed-Onset Muscle Soreness (DOMS)
Interventions: DEVICE: ThermaCare HeatWraps
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Burning Mouth Syndrome - New Diagnostic Criteria and Treatment
Status: UNKNOWN
Conditions: Burning Mouth Syndrome
Interventions: DRUG: Clonazepam 0.5 MG|DRUG: Capsaicin Topical|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Taste and Acceptance Study of FruitiVits in Children Aged 4-8 Years Following a Ketogenic Diet.
Status: COMPLETED
Conditions: Seizure Disorders
Interventions: DIETARY_SUPPLEMENT: FruitiVits
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Guided Endodontics Compared to Conventional Endodontic Treatment in Calcified Lower Incisors
Status: COMPLETED
Conditions: Dentinal Loss
Interventions: PROCEDURE: conventional endodontic treatment|PROCEDURE: Guided endodontic treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparison of 2-octyl Cyanoacrylate Skin Adhesive and Polyester Mesh for Wound Closure in Total Knee Arthroplasty, A Randomized Controlled Study
Status: ACTIVE_NOT_RECRUITING
Conditions: OsteoArthritis Knee
Interventions: DEVICE: Skin adhesive (Dermabond)|DEVICE: skin adhesive + polyester mesh (Dermabond prineo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of Efficacy and Stability of AT TORBI 709M 4-haptic Toric IOL in Cataract Surgery
Status: UNKNOWN
Conditions: Iol|Astigmatism
Interventions: PROCEDURE: AT TORBI 709M
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clofarabine in Chronic Lymphocytic Leukemia
Status: COMPLETED
Conditions: Hematologic Neoplasms|Lymphoproliferative Disorders|Leukemia|Leukemia, Lymphocytic, Chronic
Interventions: DRUG: Clofarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Aquatic Rehabilitation on Knee Function in Anterior Cruciate Ligament Reconstruction Patients.
Status: COMPLETED
Conditions: Anterior Cruciate Ligament Reconstruction|Hydrotherapy|Gait|Muscle Function
Interventions: OTHER: Aquatic Rehabilitation|OTHER: Land-based Rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Adaptation of Perioperative Satisfaction Scale in Regional Anesthesia and Investigation of Its Psychometric Properties
Status: UNKNOWN
Conditions: Scales, Repression-Sensitization|Anesthesia Awareness
Interventions: OTHER: Perioperative Satisfaction Scale in Regional Anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE