pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Oncodrivers in Malignant Pleural Effusions Associated With Non-small Cell Lung Cancer: A Prospective Study.
Status: UNKNOWN
Conditions: Malignant Pleural Effusion|Non-small Cell Lung Cancer
Interventions: DIAGNOSTIC_TEST: meassurement of PD-L1, ALK, EGFR
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Solar-Simulated Ultraviolet Radiation on Gene Expression in Unprotected and Sunscreen-Protected Skin of Healthy Adults With Fitzpatrick Skin Type II
Status: COMPLETED
Conditions: Non-melanomatous Skin Cancer|Precancerous Condition
Interventions: GENETIC: microarray analysis|PROCEDURE: biopsy|PROCEDURE: evaluation of cancer risk factors
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Clinical Study of Pyrotinib in Patients With HER2-positive Advanced Colorectal Cancer
Status: UNKNOWN
Conditions: Colorectal Cancer
Interventions: DRUG: Pyrotinib|DRUG: Pyrotinib in combination with trastuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Evaluation of the Tobacco Prevention Toolkit Healthy Futures: Alternative-to-Suspension Vaping Intervention
Status: NOT_YET_RECRUITING
Conditions: Tobacco Use Cessation|Addiction
Interventions: BEHAVIORAL: Healthy Futures: Alternative-to-Suspension Curriculum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Optimal Procedural Sequence in Same-day Bidirectional Endoscopy: A Prospective Randomized Controlled Study
Status: COMPLETED
Conditions: Endoscopy|Moderate Sedation
Interventions: PROCEDURE: EGD and colonoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Safety and Immunogenicity Study of a Liquid Pentavalent Combination Vaccine
Status: COMPLETED
Conditions: Diphtheria|Tetanus|Pertussis|Hepatitis B|Haemophilus Influenzae Type B
Interventions: BIOLOGICAL: Shan5
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Identification of Potential Biomarkers of Response to Peptide Immunotherapy for Ragweed Allergy
Status: COMPLETED
Conditions: Ragweed Allergy
Interventions: BIOLOGICAL: ToleroMune Ragweed|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Sirolimus Coated Angioplasty Versus Plain Balloon Angioplasty
Status: RECRUITING
Conditions: End Stage Renal Failure on Dialysis|Arteriovenous Graft Occlusion
Interventions: DEVICE: Sirolimus coated balloon|DEVICE: Plain balloon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Maintenance Cabozantinib+BSC Versus BSC in Children and AYA With Osteosarcoma
Status: RECRUITING
Conditions: Osteosarcoma|Osteosarcoma in Children|Osteosarcoma in Adolescents and Young Adults
Interventions: DRUG: Cabozantinib|OTHER: Best Supportive Care (BSC)|OTHER: Best Supportive Care (BSC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anti-CD22 Chimeric Receptor T Cells in Pediatric and Young Adults With Recurrent or Refractory CD22-expressing B Cell Malignancies
Status: ACTIVE_NOT_RECRUITING
Conditions: NHL|Large Cell Lymphoma|Follicular Lymphoma|ALL|B-All|B-precursor ALL|Acute Lymphoblastic Leukemia|Acute Lymphocytic Leukemia|B-Non Hodgkin Lymphoma|B-NHL
Interventions: BIOLOGICAL: CD22-CAR
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anifrolumab for Hidradenitis Suppurativa
Status: RECRUITING
Conditions: Hidradenitis Suppurativa|Acne Inversa|Hidradenitis
Interventions: DRUG: Anifrolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Metformin on Pregnancy and Miscarriage Rates in Polycystic Ovary Syndrome (PCOS)
Status: COMPLETED
Conditions: Polycystic Ovary Syndrome|Miscarriage|Infertility|Toxemia|Gestational Diabetes
Interventions: DRUG: metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vorasidenib in Combination With Temozolomide (TMZ) in IDH-mutant Glioma
Status: NOT_YET_RECRUITING
Conditions: IDH1-mutant Glioma|IDH2-mutant Glioma
Interventions: DRUG: Vorasidenib|DRUG: Temozolomide (TMZ)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: AML Patients Bearing FLT3 Mutations Based on Peripheral Blast Clearance
Status: RECRUITING
Conditions: Acute Myeloid Leukemia With FLT3/ITD Mutation
Interventions: DRUG: Cytarabine|DRUG: Daunorubicin|DRUG: Midostaurin|DRUG: Cytarabine HD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Tarceva (Erlotinib) Following Platinum-Based Chemotherapy in Patients With Advanced, Recurrent, or Metastatic Non-Small Cell Lung Cancer (NSCLC)
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: erlotinib [Tarceva]|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Inhaled Steroids at Discharge After Emergency Department Visits for Children With Uncontrolled Asthma
Status: TERMINATED
Conditions: Asthma
Interventions: DRUG: fluticasone|OTHER: Standard Asthma Discharge Instructions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Research Study to See How a New Weekly Insulin, Insulin Icodec When Given Along With Semaglutide Helps in Reducing the Blood Sugar Level in Patients With Type 2 Diabetes
Status: RECRUITING
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Insulin Icodec|DRUG: Semaglutide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Galectin Role in Periodontal Disease
Status: COMPLETED
Conditions: Gingivitis|Periodontitis
Interventions: DIAGNOSTIC_TEST: GCF sample collection|PROCEDURE: non-surgical periodontal treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Prospective Evaluation of Family Care Rituals in the ICU
Status: COMPLETED
Conditions: Stress Disorders, Post-Traumatic|Depression|Anxiety
Interventions: BEHAVIORAL: Family Care Rituals
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Application of Direct Current Transcranial stImulation, Remotely superVised in Chronic fATiguE
Status: RECRUITING
Conditions: Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
Interventions: DEVICE: home-based transcranial direct current stimulation (tDCS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low Dose of Metronomic Cyclophosphamide and Capecitabine in Pretreated HER2-negative Metastatic Breast Cancer
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: DRUG: metroCX
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Abdominal Breathing for Depression, Anxiety, Heart Rate Variability in Obstructive Sleep Apnea Patients
Status: COMPLETED
Conditions: Obstructive Sleep Apnea
Interventions: BEHAVIORAL: Abdominal breathing training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endometriosis Trial: Study of NBI-56418 in Endometriosis
Status: COMPLETED
Conditions: Endometriosis
Interventions: DRUG: NBI-56418 (GnRH antagonist)|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Pomalidomide Combined With Modified DA-EPOCH and Rituximab in KSHV-Associated Lymphomas
Status: WITHDRAWN
Conditions: Large Cell Lymphoma Arising in KSHV-associated Multicentric Castleman Disease|Primary Effusion Lymphoma
Interventions: DRUG: Pomalidomide|DRUG: Rituximab|DRUG: Prednisone|DRUG: Etoposide|DRUG: Doxorubicin|DRUG: Vincristine|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ATTUNE Single-Use Instrumentation vs. ATTUNE Reusable Instrumentation in Primary Total Knee Arthroplasty
Status: COMPLETED
Conditions: Osteoarthritis|Post-traumatic Arthritis
Interventions: DEVICE: ATTUNE TKA with ATTUNE RUI|DEVICE: ATTUNE TKA with ATTUNE SUI
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Use of Medical-Expulsive Therapy With Alfuzocine xl 10mg x1/d for Distal Ureterolithiasis.a Randomized Prospective Study
Status: UNKNOWN
Conditions: Distal Ureterolithiasis
Interventions: DRUG: Alfuzocine XL 10 mg once a day
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Treatment of Mitral Regurgitation Using a Minimally Invasive Approach With the HARPOON Device.
Status: TERMINATED
Conditions: Mitral Regurgitation
Interventions: DEVICE: HARPOON Beating Heart Mitral Valve Repair System (MVRS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Chemotherapy Versus Neoadjuvant Chemoradiotherapy for Resectable Locally Advanced Esophageal Cancer (HCHTOG1903)
Status: RECRUITING
Conditions: Esophageal Squamous Cell Carcinoma
Interventions: DRUG: Paclitaxel, Cisplatin|RADIATION: neoadjuvant chemoradiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Women Supporting Women to Improve Infant and Child Feeding Practices
Status: RECRUITING
Conditions: Undernutrition|Healthy Nutrition|Health Behavior|Health Knowledge, Attitudes, Practice|Child Malnutrition|Child Rearing|Health Care Seeking Behavior
Interventions: BEHAVIORAL: Community Sensitization|BEHAVIORAL: 28-day PD/Hearth Sessions|BEHAVIORAL: Supplemental Print Information
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Smoking Cessation in Subjects With Mild-to-moderate Chronic Obstructive Pulmonary Disease (COPD).
Status: COMPLETED
Conditions: Smoking Cessation
Interventions: DRUG: placebo|DRUG: Varenicline Tartarate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study on Amprenavir in Combination With Other Anti-HIV Drugs in HIV-Positive Patients
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Indinavir sulfate|DRUG: Abacavir sulfate|DRUG: Amprenavir|DRUG: Nelfinavir mesylate|DRUG: Efavirenz|DRUG: Levocarnitine|DRUG: Adefovir dipivoxil|DRUG: Saquinavir
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics and Safety of 'CG-745 IV' and 'CG-750' in Healthy Male Adults
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: CG-745 IV Solution|DRUG: CG-750 125mg capsule|OTHER: PO Placebo|OTHER: IV Placebo: 0.9 % normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Three Methods of PEEP Titration During One Lung Ventilation in Prone Position
Status: RECRUITING
Conditions: One Lung Ventilation
Interventions: PROCEDURE: constant PEEP|PROCEDURE: Driving pressure guided PEEP|PROCEDURE: oxygenation method guided PEEP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Bevacizumab (Avastin) in Treatment of Acute NMO Exacerbations
Status: COMPLETED
Conditions: Neuromyelitis Optica|Neuromyelitis Optica Spectrum Disorder
Interventions: DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open Label Extension Study of Conatumumab and Ganitumab (AMG 479)
Status: COMPLETED
Conditions: Advanced Solid Tumors|Carcinoid|Colorectal Cancer|Locally Advanced|Lymphoma|Metastatic Cancer|Non-Small Cell Lung Cancer|Sarcoma|Solid Tumors
Interventions: DRUG: Modified FOLFOX6|BIOLOGICAL: Conatumumab|BIOLOGICAL: Ganitumab|BIOLOGICAL: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Internet-delivered Cognitive-behaviour Therapy for Child and Adolescent Body Dysmorphic Disorder
Status: RECRUITING
Conditions: Body Dysmorphic Disorders
Interventions: BEHAVIORAL: Internet-delivered cognitive-behaviour therapy (ICBT)|BEHAVIORAL: Internet-delivered relaxation treatment (IRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acupuncture for Pain in the Emergency Department
Status: WITHDRAWN
Conditions: Musculoskeletal Pain|Pain
Interventions: PROCEDURE: Auricular Acupuncture|DEVICE: Acupuncture|PROCEDURE: Placebo Acupuncture|DRUG: hydrocodone / acetaminophen 5mg/325mg|DRUG: Placebo Pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Time-lapse Evaluation of Embryo Development After Stimulation With One of Two Different Gonadotrophins.
Status: TERMINATED
Conditions: Patients for In Vitro Fertilization(IVF)Treatment
Interventions: DRUG: HP-HMG|DRUG: recombinant FSH
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate MRG003 vs Cetuximab/Methotrexate in in the Treatment of Patients With RM-SCCHN
Status: NOT_YET_RECRUITING
Conditions: Squamous Cell Carcinoma of the Head and Neck
Interventions: DRUG: MRG003|DRUG: Cetuximab injection|DRUG: Methotrexate Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Gain Information How Well Dexpanthenol Dermal Spray Helps the Skin to Recover After a Peeling in the External Genital Area of Women
Status: COMPLETED
Conditions: Skin Recovery
Interventions: DRUG: BAY207543 (Bepanthol, Bepantol® Derma Spray)|OTHER: Semisolid vaseline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Ibrutinib and Brentuximab Vedotin in Treating Patients With Relapsed or Refractory Hodgkin Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Recurrent Hodgkin Lymphoma|Refractory Hodgkin Lymphoma
Interventions: DRUG: Brentuximab Vedotin|DRUG: Ibrutinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transversus Abdominis Plane(TAP) Block, Local Infiltration and Intravenous Dexketoprofen in Inguinal Hernia Repair
Status: COMPLETED
Conditions: Inguinal Hernia
Interventions: OTHER: Transversus abdominis plane block|OTHER: Local anesthetic infiltration|OTHER: Intravenous dexketoprofen
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: To Evaluate the Effect of Gemfibrozil on the Pharmacokinetics and Pharmacodynamics of a Single Dose of AZD1656
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: AZD1656|DRUG: Gemfibrozil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Intact and Disrupted Milk Fat Globule Membrane on Postprandial Metabolic Response to High-fat Dairy in Healthy Individuals
Status: RECRUITING
Conditions: Postprandial Lipid Metabolism
Interventions: DIETARY_SUPPLEMENT: Sandwich with butter-like dairy product (40g milk fat) with intact MFGM. One sandwich for breakfast and one sandwich for lunch.|DIETARY_SUPPLEMENT: Sandwich with butter-like dairy product (40g milk fat) with disrupted MFGM. One sandwich for breakfast and one sandwich for lunch.|DIETARY_SUPPLEMENT: Sandwich with butter-like dairy product (40g milk fat) without MFGM. One sandwich for breakfast and one sandwich for lunch.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Building a Bridge (BAB) Between Clinical and Community Care
Status: COMPLETED
Conditions: Caregiver Burden
Interventions: BEHAVIORAL: Options Counselor Health Educator (OC-HE) Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Ball Squeezing and Adhesive Remover Use on Pain and Fear in Children Aged 6-9 Years During the Removal of Peripheral Intravenous Cannula
Status: RECRUITING
Conditions: Procedural Pain|Fear of Pain
Interventions: OTHER: Standard Care|OTHER: Adhesive Remover Spray|BEHAVIORAL: Ball Squeezing + Adhesive Remover Spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Resistance Mechanism of Trastuzumab Deruxtexan in HER2 Positive Breast Cancer Patients.
Status: RECRUITING
Conditions: HER2-positive Breast Cancer
Interventions: DIAGNOSTIC_TEST: GeoMx data analysis with clinical outcome
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: A Study to Evaluate the Efficacy of the Nasal Antiseptic, PrevinC, When Administered for the RiskReduction of Rhinitis in Subjects Who Work for Child Day Care Centers
Status: COMPLETED
Conditions: Upper Respiratory Infections
Interventions: OTHER: PrevinC|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Irbesartan/Hydrochlorothiazide National Taiwan University Hospital Listing
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Irbesartan/Hydrochlorothiazide|DRUG: Irbesartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of a Pre-cataract Surgical Ocular Hygiene Regime on Microbial Load, Tear Osmolarity, Dry Eye, and Inflammatory Markers
Status: NOT_YET_RECRUITING
Conditions: Dry Eye|Dry Eye Syndromes|Cataract
Interventions: DIETARY_SUPPLEMENT: Omega-3|DRUG: Trehalose|DRUG: Zocular Eyelid System Treatment|OTHER: Blephadex cleansing eyelid wipes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: To Evaluate the Efficacy, Safety, Tolerability and Pharmacokinetics of a Single Dose Regimen of Ferroquine and Artefenomel in Adults and Children With Uncomplicated Plasmodium Falciparum Malaria
Status: TERMINATED
Conditions: Plasmodium Falciparum Infection
Interventions: DRUG: Ferroquine SSR97193|DRUG: Artefenomel|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Paricalcitol in Reducing Parathyroid Hormone (PTH) Levels in X-linked Hypophosphatemic Rickets
Status: COMPLETED
Conditions: Hypophosphatemia, Familial|Hyperparathyroidism
Interventions: DRUG: Paricalcitol|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Using Vedolizumab-800CW to Gain Insight Into Local Drug Distribution and Mucosal Target Cells in IBD Patients
Status: COMPLETED
Conditions: Crohn Disease|Colitis, Ulcerative
Interventions: DRUG: Fluorescence molecular imaging procedure using vedolizumab-800CW|OTHER: Fluorescence molecular imaging procedure without prior administration of vedolizumab-800CW|COMBINATION_PRODUCT: Fluorescence molecular imaging procedure using vedolizumab-800CW with prior administration of unlabeled vedolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Dexmedetomidine on Basal Ganglia Neuronal Activity in Parkinson's Disease
Status: UNKNOWN
Conditions: Dexmedetomidine|Deep Brain Stimulation|Parkinson Disease
Interventions: DRUG: Dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: To Evaluate the Efficacy of Diquafosol Sodium in the Treatment of MGD in Different Treatment Pattern
Status: RECRUITING
Conditions: Dry Eye|Meibomian Gland Dysfunction
Interventions: PROCEDURE: Warm compresses|DRUG: 3% Diquafosol Sodium Eye Drops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multiple Ascending Dose Study in Healthy Subjects to Evaluate the Safety, Tolerability, and Pharmacokinetics of LY03005
Status: COMPLETED
Conditions: Major Depressive Disorder, Recurrent, Unspecified
Interventions: DRUG: LY03005|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Combination Chemotherapy and Trastuzumab in Treating Women With Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: BIOLOGICAL: trastuzumab|DRUG: carboplatin|DRUG: paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of the Sub-gonal Arterial Revascularization of the Lower Limbs in Critical Ischemia by Venous Allograft Stored at + 4 ° C (ERAV)
Status: UNKNOWN
Conditions: Venous Allogeneic Transplant|Occlusive Peripheral Arterial Disease
Interventions: BEHAVIORAL: Questionnaires on quality of life after surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Photobiomodulation and the Intralesional Administration of Corticoid in the Keloid Surgery.
Status: COMPLETED
Conditions: Keloid|Cicatrix
Interventions: DEVICE: Photobiomodulation with blue led|DRUG: Triamcinolone Hexacetonide|DEVICE: Sham LED
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing Real-time fMRI Neurofeedback Versus Sham for Altering Limbic and Eating Disturbances in Anorexia Nervosa
Status: COMPLETED
Conditions: Anorexia|Anorexia Nervosa
Interventions: PROCEDURE: Real-Time Functional Magnetic Resonance Imaging (RT-fMRI)|PROCEDURE: Sham Procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Allogeneic Adipose Derived Stem Cells for Werdnig Hoffman Patients
Status: UNKNOWN
Conditions: Infantile Spinal Muscular Atrophy, Type I [Werdnig- Hoffman]
Interventions: BIOLOGICAL: Adipose derived mesenchymal stem cell
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Prospective Randomized Controlled Trial of Dual-Mobility Components in Primary THA
Status: ACTIVE_NOT_RECRUITING
Conditions: Serum Metal Levels, Specifically Cobalt, Chromium, and Titanium
Interventions: DEVICE: Dual mobility cohort|DEVICE: Conventional cohort
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Endoscopic Stricturotomy Versus Endoscopic Balloon Dilatation in Patients With Crohn's Disease and Symptomatic Small Bowel Stricture
Status: RECRUITING
Conditions: Crohn Disease|Stricture; Bowel|Endoscopy, Gastrointestinal
Interventions: PROCEDURE: Endoscopic stricturotomy|PROCEDURE: Endoscopic balloon dilatation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Efficacy and Safety of Tiropramide and Octylonium in the Treatment of Irritable Bowel Syndrome
Status: UNKNOWN
Conditions: Irritable Bowel Syndrome
Interventions: DRUG: Tiropramide HCl 100mg|DRUG: Octylonium bromide 20mg
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Diffusion-Weighted MRI in Staging Patients With Localized Prostate Cancer
Status: COMPLETED
Conditions: Adenocarcinoma of the Prostate|Stage IIA Prostate Cancer|Stage IIB Prostate Cancer
Interventions: PROCEDURE: diffusion-weighted magnetic resonance imaging|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Remote Ischemic Preconditioning in High Risk Cardiovascular Surgery Patients
Status: COMPLETED
Conditions: Death|Stroke|Low Cardiac Output Syndrome|Myocardial Infarction|Renal Failure|Pulmonary Failure
Interventions: OTHER: Remote ischemic preconditioning stimulus|OTHER: control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of 6-week Strawberry Supplementation on Insulin Action (STR2)
Status: COMPLETED
Conditions: Insulin Resistance|Nutritional Disease|Metabolic Disease
Interventions: DIETARY_SUPPLEMENT: Strawberry|DIETARY_SUPPLEMENT: Placebo1|DIETARY_SUPPLEMENT: Placebo2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Co-administration Study in Patients With Elevated Cholesterol and Coronary Heart Disease (0653-802)(COMPLETED)
Status: COMPLETED
Conditions: Hypercholesterolemia|Coronary Disease
Interventions: DRUG: MK0653, ezetimibe|DRUG: Comparator: ezetimibe, placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Implant Abutment Dis-/Reconnection and Peri-Implant Marginal Bone Loss.
Status: COMPLETED
Conditions: Alveolar Bone Loss
Interventions: PROCEDURE: Implant surgery|DEVICE: Three abutment dis-/reconnections.|DEVICE: No abutment dis-/reconnections.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Canola Oil Multicentre Intervention Trial
Status: COMPLETED
Conditions: Metabolic Syndrome
Interventions: OTHER: Corn and safflower oil|OTHER: Canola oil|OTHER: High oleic acid canola oil|OTHER: DHA enriched high oleic acid canola oil|OTHER: Flax and safflower oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Mother-Infant Psychoanalysis Project of Stockholm (MIPPS)- Follow-up at 4½ Years
Status: UNKNOWN
Conditions: Mother-child Relationship Disturbances
Interventions: BEHAVIORAL: Mother-Infant Psychoanalytic tmt|BEHAVIORAL: Child Health Centre care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Does Alkalinization Reduce Perceived Pain Levels During Sentinel Lymph Node Imaging?
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Standard of Care First|DRUG: ph Altered first
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: RECOVER Clinical Pathway for Pediatric Concussion
Status: COMPLETED
Conditions: Concussion, Brain|Pediatric Disorder|Mild Traumatic Brain Injury
Interventions: OTHER: Pediatric Acute Care Concussion Clinical Pathway
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Single Dose, Tolerance and Pharmacokinetic Study in Obese or Overweight Type 2 Diabetic Volunteers
Status: COMPLETED
Conditions: Diabetes Mellitus|Obesity
Interventions: DRUG: Trodusquemine (MSI-1436)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Adjuvant Chemotherapy With Paclitaxel and Cisplatin in Lymph Node-Positive Thoracic Esophageal Squamous Cell Carcinoma
Status: COMPLETED
Conditions: Esophageal Cancer
Interventions: DRUG: paclitaxel; cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of Variations of Systemic Venous Return on Analgesia Nociception Index (ANI) During General Anaesthesia
Status: COMPLETED
Conditions: Hypovolemia|Somatic Pain
Interventions: PROCEDURE: noxious stimulus|PROCEDURE: change in operating table slope: head-down tilt position|PROCEDURE: change in operating table slope: head-up tilt position
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Evaluate OPTI-BIOME™ Bacillus Subtilis MB40 on Abdominal Discomfort, Gas and Bloating in a Healthy Population
Status: COMPLETED
Conditions: Bloating
Interventions: DIETARY_SUPPLEMENT: OPTI-BIOME™ Bacillus subtilis MB40|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Comparison of Certoparin and Unfractionated Heparin in the Prevention of Thromboembolic Events in Acutely Ill Medical Patients
Status: COMPLETED
Conditions: Thromboembolism
Interventions: DRUG: Certoparin|DRUG: Unfractionated Heparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Melatonin and Osteogenic Loading on Osteopenia
Status: ACTIVE_NOT_RECRUITING
Conditions: Osteopenia
Interventions: DRUG: Melatonin 5 mg|DEVICE: Osteogenic loading|DEVICE: Mock for Osteogenic Loading|DRUG: Placebo (plant fiber) for melatonin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Metformin, Targeting Cancer Stem Cells for Prevention of Relapse in Gynecologic Patients
Status: COMPLETED
Conditions: Ovarian, Fallopian Tube, and Primary Peritoneal Cancer
Interventions: DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Streptococcus Mutans Pathogenicity by Real-time Polymerase Chain Reaction (PCR) in High Caries Risk Patients
Status: UNKNOWN
Conditions: Streptococcus Mutans
Interventions: DRUG: Sage extract mouthwash|DRUG: Chlorohexidine based mouthwash
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Additive Homeopathy in Cancer Patients
Status: COMPLETED
Conditions: Malignant Tumors
Interventions: DRUG: Additive classical homeopathy|DRUG: Homeopathic Placebo globules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of High-Intensity Interval Training on Glucose Variability and Atrial Fibrillation Symptoms
Status: COMPLETED
Conditions: Atrial Fibrillation|Type 2 Diabetes
Interventions: BEHAVIORAL: High-intensity interval training + standard care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Effect of Oral Enteral Nutrition on Severe Traumatic Brain Injury
Status: COMPLETED
Conditions: Traumatic Brain Injury
Interventions: DEVICE: Nasogastric tube feeding|DEVICE: Intermittent Oro-esophageal Tube Feeding|BEHAVIORAL: Rehabilitation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Exercise on Blood Coagulation in Persons With Chronic Spinal Cord Injury
Status: COMPLETED
Conditions: Cardiovascular Disease|Spinal Cord Injury
Interventions: DEVICE: ERGYS BikeFunctional Electrical Stimulation Ergometry
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Alkali Therapy in Chronic Kidney Disease
Status: COMPLETED
Conditions: Chronic Kidney Disease|Metabolic Acidosis
Interventions: DRUG: Sodium bicarbonate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intraarticular Injections of the Hip and Knee With Triamcinolone Versus Ketorolac: A Randomized Controlled Trial
Status: COMPLETED
Conditions: Arthritis Knee|Arthritis of Hip
Interventions: DRUG: Ketorolac Intraarticular Injection|DRUG: Triamcinolone Intraarticular Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Role of Tranexamic Acid in Reducing Post Operative Hand Edema After Hand and Wrist Surgery
Status: UNKNOWN
Conditions: Hand Injuries and Disorders|Distal Radius Fracture|Dupuytren Contracture
Interventions: DRUG: Tranexamic acid|PROCEDURE: Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Campania Registry On Peripheral Artery Disease
Status: RECRUITING
Conditions: Peripheral Artery Disease
Interventions: DIAGNOSTIC_TEST: Vascular ultrasound or other imaging methods according to current guidelines|DIAGNOSTIC_TEST: Laboratory tests|DRUG: Medical treatment according to current guidelines|PROCEDURE: Endovascular od surgical peripheral revascularizations
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Cardenilimab Combined With Lenvatinib in Patients With Perioperative Resectable Clear Cell Renal Cell Carcinoma.
Status: NOT_YET_RECRUITING
Conditions: Resectable Clear Cell Carcinoma of the Kidney
Interventions: DRUG: cardonilizumab combined with renvastinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Effectiveness Between the Combination of Lidocaine Sprayed at Laryngeal Inlet and on the Cuff of Endotracheal Tube Versus Intravenous Lidocaine for Reducing Cough During Extubation
Status: COMPLETED
Conditions: Reducing Cough During Extubation
Interventions: DRUG: 10% lidocaine sprayed|DRUG: 2% lidocaine intravenous
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transdermal Clonidine in the Treatment of Severe Hyperemesis Gravidarum
Status: COMPLETED
Conditions: Hyperemesis Gravidarum
Interventions: DRUG: Clonidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Predicting Female Pelvic Tilt and Lumbar Angle Using Machine Learning in Case of Urinary Incontinence and Sexual Dysfunction
Status: COMPLETED
Conditions: The Purpose of This Study is to Predicting Female Pelvic Tilt and Lumbar Angle Using Machine Learning in Case of Urinary Incontinence and Sexual Dysfunction
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: PRO#1278: Fludarabine and Busulfan vs. Fludarabine, Busulfan and Total Body Irradiation
Status: TERMINATED
Conditions: Myeloid Malignancies|Acute Myelogenous Leukemia|Chronic Myelogenous Leukemia|Myeloproliferative Disorders|Myelodysplastic Syndrome
Interventions: DRUG: Fludarabine and Busulfan plus/minus Total Body Irradiation (low dose)|DRUG: Fludarabine and Busulfan + Low Dose Total Body Irradiation (LD TBI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fermented Milk on the Appearance of Common Winter Infectious Diseases
Status: COMPLETED
Conditions: Acute Gastroenteritis|Upper Respiratory Tract Infections
Interventions: DIETARY_SUPPLEMENT: Fermented milk|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Hot Water Immersion as a Heat Acclimation Strategy in Older Adults
Status: COMPLETED
Conditions: Hyperthermia|Heat Exposure|Heat Stress|Thermoregulation|Aging
Interventions: OTHER: Heat acclimation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: SMART: Somatotrophics, Memory, and Aging Research Trial
Status: COMPLETED
Conditions: Aging|Mild Cognitive Impairment
Interventions: DRUG: TH9507 human growth hormone releasing hormone (GHRH)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of Mycophenolic Acid Versus Azathioprine in the Treatment of Corticosteroid-refractory Myasthenia Gravis
Status: UNKNOWN
Conditions: Myasthenia Gravis
Interventions: DRUG: Mycophenolic acid|DRUG: AZA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effectiveness of Ischemic Pre-conditioning on the Morbidity and Mortality of Open Surgery of Thoracoabdominal Aortic Aneurysms.
Status: COMPLETED
Conditions: Aortic Aneurysm|Surgery
Interventions: PROCEDURE: clamping with pre-conditioning (PCl)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comprehensive Self-management Support for COPD Patients
Status: COMPLETED
Conditions: COPD|Self-management Behaviors
Interventions: BEHAVIORAL: Self-management barrier support|BEHAVIORAL: Basic COPD Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Antioxidant Supplements in the Reversal of Schistosomal Peri-portal Fibrosis
Status: UNKNOWN
Conditions: Schistosomiasis|Liver Fibrosis|Periportal Fibrosis|Oxidative Stress
Interventions: DIETARY_SUPPLEMENT: Praziquantel+antioxidant suppl|OTHER: Praziquantel + placebo 2mths then antioxidant for 10 mths|DIETARY_SUPPLEMENT: Praziquantel therapy and placebo as supplement|DIETARY_SUPPLEMENT: Praziquantel+antioxidant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of SIMBRINZA® Suspension as an Added Therapy to a Prostaglandin Analogue
Status: COMPLETED
Conditions: Ocular Hypertension|Open Angle Glaucoma
Interventions: DRUG: Brinzolamide 1%/brimonidine 0.2% ophthalmic suspension|DRUG: Vehicle|DRUG: Prostaglandin analogue
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Symmetrical Versus Asymmetrical Surgery for Asymmetrical Inferior Oblique Overaction
Status: UNKNOWN
Conditions: Strabismus
Interventions: PROCEDURE: Symmetrical IO weakening|PROCEDURE: Asymmetrical IO weakening
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy Following Surgery in Treating Women With Early Stage Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: CMF regimen|DRUG: cyclophosphamide|DRUG: epirubicin hydrochloride|DRUG: fluorouracil|DRUG: methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Technology-based Training Tool for PHAT Life
Status: RECRUITING
Conditions: HIV Infection|Sexually Transmitted Infections|Implementation
Interventions: BEHAVIORAL: Training Tool for Preventing HIV/AIDS among Teens (PHAT) Life
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Triathlon Tritanium Knee Outcomes Study
Status: TERMINATED
Conditions: Arthroplasty, Replacement, Knee
Interventions: DEVICE: Triathlon Tritanium Knee|DEVICE: Triathlon Knee
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability of DMT in Healthy Adults
Status: COMPLETED
Conditions: Safety Issues|Healthy Volunteers
Interventions: DRUG: N,N-Dimethyltryptamine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An Alternative Technique for Measuring Blood Pressure
Status: ENROLLING_BY_INVITATION
Conditions: Healthy
Interventions: DEVICE: blood pressure measurement starting with standard technique or alternative new technique. manual sphygmomanometer will be used.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Clinical Study in Health Subjects to Evaluate 9MW1411 Injection
Status: COMPLETED
Conditions: Staphylococcus Aureus Infection
Interventions: COMBINATION_PRODUCT: 9MW1411 injection|COMBINATION_PRODUCT: 9MW1411 injection placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Statistical and Epidemiological Study Based on the Use of Convalescent Plasma for the Management of Patients With COVID-19
Status: UNKNOWN
Conditions: COVID-19 Pneumonia|Convalescent Plasma
Interventions: BIOLOGICAL: Convalescent plasma
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Intraoperative Electron Beam Radiotherapy Boost in Treating Patients With Stage I-II Breast Cancer Undergoing Surgery With Reconstruction
Status: RECRUITING
Conditions: Stage IA Breast Cancer|Stage IB Breast Cancer|Stage IIA Breast Cancer|Stage IIB Breast Cancer
Interventions: RADIATION: Electron Beam Therapy|PROCEDURE: Lumpectomy|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration|RADIATION: Radiation Therapy|PROCEDURE: Reconstructive Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: COMBISTRAT: AmBisome® in Combination With Caspofungin for the Treatment of Invasive Aspergillosis
Status: COMPLETED
Conditions: Invasive Aspergillosis
Interventions: DRUG: Ambisome|DRUG: caspofungin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of a Quadruple Ultra-low-dose Treatment for Hypertension
Status: ACTIVE_NOT_RECRUITING
Conditions: Hypertension
Interventions: DRUG: QUARTET LDQT|DRUG: Candesartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of BIIB091 Formulations in Healthy Participants
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: BIIB091|DRUG: Rabeprazole|DRUG: Itraconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT