pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Study to Investigate the Absorption, Metabolism, and Excretion of [14C]-GDC-0980 Following Single Oral Dose Administration in Healthy Postmenopausal Female Subjects
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: [14C]-GDC-0980
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Carvedilol, Endoscopic Variceal Ligation or Combination of Both for Prevention of First Variceal Bleed in Child's B & C Cirrhosis
Status: UNKNOWN
Conditions: Cirrhosis
Interventions: DRUG: Carvedilol|PROCEDURE: Endoscopic Variceal Ligation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 2D/3D Imaging to Analyze the Regeneration Rate of Autologous Bone
Status: NOT_YET_RECRUITING
Conditions: Alveolar Ridge Preservation
Interventions: PROCEDURE: Autologous Tooth Root|DRUG: Vit.D3|OTHER: bone graft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Performance of MAgnetic Gastrointestinal Universal Septotome for Treatment of Candy Cane Syndrome
Status: RECRUITING
Conditions: Blind Loop Syndrome Postoperative|Candy Cane Syndrome
Interventions: DEVICE: MAGUS placement
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Erythropoietin on Alveolar Ridge Preservation
Status: RECRUITING
Conditions: Alveolar Bone Loss
Interventions: DRUG: Erythropoietin carried on chitosan carrier|OTHER: chitosan carrier
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Long Term Prospective Study Evaluating Effectiveness of Narrow Margins for Low-Risk Head and Neck Basal Cell Carcinomas
Status: UNKNOWN
Conditions: Basal Cell Carcinoma
Interventions: PROCEDURE: Low-Risk BCC Excisional Margins
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High Dose Interval Vitamin D Supplementation in Patients With Inflammatory Bowel Disease Receiving Biologic Therapy
Status: RECRUITING
Conditions: Inflammatory Bowel Disease|Crohn Disease|Ulcerative Colitis|Vitamin D Deficiency
Interventions: DIETARY_SUPPLEMENT: vitamin D3
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Learn About Venous Thromboembolism (VTE) Treatment With Rivaroxaban in Japanese Patients Using a Claims Database
Status: COMPLETED
Conditions: Treatment of Venous Thromboembolism
Interventions: DRUG: Rivaroxaban (Xarelto, BAY59-7939)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Fluid Restriction After Stapled Hemorrhoidopexy
Status: COMPLETED
Conditions: Fluid Restriction
Interventions: DRUG: 1000 mL 0.9% sterile saline|DRUG: 250 mL 0.9% sterile saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Robotic OCT for ER Anterior Eye Exams
Status: NOT_YET_RECRUITING
Conditions: Develop and Test Robotically Assisted Imaging System for the Front of the Eye
Interventions: DEVICE: Robotically Aligned Eye Imaging System
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Cardiovascular Risk Reduction in Epilepsy
Status: WITHDRAWN
Conditions: Epilepsy|Hypertension|Hyperlipidemia (E.G., Hypercholesterolemia)
Interventions: DRUG: Neurologist Initiated Treatment|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study to Assess the Safety, Tolerability, and Pharmacokinetics of Single and Multiple Doses of Cefiderocol in Hospitalized Pediatric Participants
Status: COMPLETED
Conditions: Gram-negative Bacterial Infections|Bloodstream Infections (BSI)|Complicated Intra-abdominal Infection (cIAI)|Hospital Acquired Pneumonia (HAP)|Ventilator-acquired Pneumonia|Complicated Urinary Tract Infection (cUTI)|Sepsis
Interventions: DRUG: Cefiderocol|DRUG: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study in Healthy Men to Test How Itraconazole Influences the Amount of BI 1810631 in the Blood
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BI 1810631|DRUG: Itraconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: NEoadjuvant Gefitinib fOllowed by Surgery and gefiTinib In unresectAble sTage III NSCLC With EGFR Mutations.
Status: SUSPENDED
Conditions: Lung Cancer
Interventions: PROCEDURE: Gefitinib-surgery-gefitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Comparison of Two Multifocal Contact Lenses Made of Silicone Hydrogel Materials
Status: COMPLETED
Conditions: Myopia|Presbyopia
Interventions: DEVICE: Lotrafilcon B contact lens|DEVICE: Comfilcon A contact lens
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: 4-EVER : a Trial Investigating the Safety of 4F Endovascular Treatment of Infra-Inguinal Arterial Stenotic Disease
Status: COMPLETED
Conditions: Peripheral Vascular Disease|Claudication
Interventions: DEVICE: 4F portfolio products from Biotronik
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multicenter Trial Comparing REMICADE (Infliximab) and Placebo in the Prevention of Recurrence in Crohn's Disease (CD) Patients Undergoing Surgical Resection Who Are at an Increased Risk of Recurrence
Status: TERMINATED
Conditions: Crohn's Disease
Interventions: BIOLOGICAL: Infliximab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of Regional Anaesthesia Methods for Femoral Neck Fracture Surgery
Status: NOT_YET_RECRUITING
Conditions: Femoral Neck Fractures|Regional Anesthesia
Interventions: PROCEDURE: hypobaric spinal anaesthesia|PROCEDURE: lumbar plexus block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Promotion and Implementation Project of HIV Pre-Exposure Prophylaxis Among High Risk Population
Status: ACTIVE_NOT_RECRUITING
Conditions: HIV Preexposure Prophylaxis
Interventions: OTHER: WeChat mobile mini-application
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Long Term Follow-Up Study 16-20 Years After Hepatitis B Vaccination in Newborns of Mothers Who Were Seropositive for Hepatitis B Envelope Antigen (HBeAg) & Hepatitis B Surface Antigen (HBsAg)
Status: COMPLETED
Conditions: Hepatitis B
Interventions: PROCEDURE: Blood sampling
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety, Tolerability, and Immunogenicity of V419 in Healthy Infants When Given at 2, 3, 4 and 12 Months (V419-007)
Status: COMPLETED
Conditions: Bacterial Infections|Virus Diseases
Interventions: BIOLOGICAL: V419|BIOLOGICAL: INFANRIX™ hexa|BIOLOGICAL: RotaTeq|BIOLOGICAL: Prevenar 13|BIOLOGICAL: ProQuad™
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Quinolone Prophylaxis for the Prevention of BK Virus Infection in Kidney Transplantation: A Pilot Study
Status: COMPLETED
Conditions: Disease Due to BK Polyomavirus|Kidney Transplant Infection
Interventions: DRUG: Levofloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of Palbociclib in Combination With Fulvestrant or Tamoxifen as Treatment for Metastatic Breast Cancer
Status: COMPLETED
Conditions: Metastatic Breast Cancer|Hormone Receptor Positive
Interventions: DRUG: Palbociclib|DRUG: Tamoxifen|DRUG: Fulvestrant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SPI-62 as a Treatment for Hypercortisolism Related to a Benign Adrenal Tumor
Status: ACTIVE_NOT_RECRUITING
Conditions: Autonomous Cortisol Secretion (ACS)|ACTH-Independent Cushing Syndrome|ACTH-Independent Adrenal Cushing Syndrome, Somatic
Interventions: DRUG: SPI-62 dose
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: STAY-STRONG Study of Exercise Training During Chemotherapy
Status: RECRUITING
Conditions: Lymphoma, B-Cell|Lymphoma, Hodgkin|Exercise|Body Composition|Physical Functional Performance|Quality of Life|Sarcopenia|Muscle, Skeletal|Patient Reported Outcome Measures
Interventions: BEHAVIORAL: Resistance Exercise Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: VisAR Augmented Reality Navigation of Ventriculostomy
Status: NOT_YET_RECRUITING
Conditions: Obstructive Hydrocephalus|Subarachnoid Hemorrhage|Brain Trauma
Interventions: DEVICE: VisAR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: UVB-induced Treg Cells Exert Antigen-specific Suppression Through LAG-3
Status: RECRUITING
Conditions: Psoriasis|Atopic Dermatitis
Interventions: RADIATION: UVB treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of Bovine Carotid Artery and Expanded Polytetrafluoroethylene (ePTFE) for Permanent Hemodialysis Access
Status: COMPLETED
Conditions: Kidney Failure|Renal Dialysis
Interventions: PROCEDURE: Grafts placement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Investigate the Clinical and Parasiticidal Activity and Pharmacokinetics of Different Doses of Artefenomel and Ferroquine in Patients With Uncomplicated Plasmodium Falciparum Malaria
Status: COMPLETED
Conditions: Plasmodium Falciparum Infection
Interventions: DRUG: Artefenomel (OZ439)|DRUG: Ferroquine (SSR97193)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Probiotics Containing Yogurts on the Composition of Biofilms in Patients Under Orthodontic Treatment
Status: COMPLETED
Conditions: Dental Caries|Oral Health
Interventions: DIETARY_SUPPLEMENT: Yogurt containing probiotics|DIETARY_SUPPLEMENT: Placebo yogurt
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of a Functional Exercise Program Associated With Low Level Laser Therapy on Fibromyalgia
Status: COMPLETED
Conditions: Fibromyalgia
Interventions: OTHER: Functional Exercise|RADIATION: Low Level Laser Therapy|RADIATION: Placebo Low Level Laser Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of an Early and Extended Rehabilitation Program Combining Individually Tailored Nutrition and Physical Activities on Patient Outcomes After Invasive Mechanical Ventilation and Vasopressor Therapy in the ICU
Status: NOT_YET_RECRUITING
Conditions: Mechanical Ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Added Value of N Acetyle Cysteine to Clomiphene Citrate in PCO
Status: COMPLETED
Conditions: PCO
Interventions: DRUG: Clomiphene plus metformin plus N acetyle cysteine in arm number 1|DRUG: Clomiphene citrate plus metformin with chromium|DRUG: clomiphene citrate plus metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Therapeutic Effect and Safety of Mifepristone in the Treatment of Adenomyosis
Status: COMPLETED
Conditions: Adenomyosis
Interventions: DRUG: Mifepristone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mastiha or Mastiha Water in Functional Dyspepsia
Status: RECRUITING
Conditions: Functional Dyspepsia
Interventions: DIETARY_SUPPLEMENT: Mastiha water|DIETARY_SUPPLEMENT: Mastiha capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Scalable Model for Promoting Functioning and Well-Being Among Veterans With a History of Mental Health Challenges Via Meaningful Social Interactions: Project V-SPEAK!
Status: COMPLETED
Conditions: Depression, Anxiety|PTSD
Interventions: OTHER: Intervention (videoconferencing)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Rabies mAb CBB 1 Combination Vaccine in Healthy People With Antibody Neutralization Activity and Safety Phase Clinical Trials
Status: NOT_YET_RECRUITING
Conditions: Rabies Virus Infection
Interventions: DRUG: Natural full human monoclonal antibody CBB 1 injection 50.0µg/kg|DRUG: Natural full human monoclonal antibody CBB 1 injection 100.0µg/kg|DRUG: Rabies Human Immunoglobulin (HRIG)|BIOLOGICAL: Lyophilized rabies vaccine for human use (Vero cells)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Phase IV Randomised Double-masked Clinical Trial: Assessing Morning Versus Evening Dosing of a Fixed Dose Combination of Travoprost 0.004% / Timolol Maleate 0.5% in Patients With Primary Open-angle Glaucoma or Ocular Hypertension
Status: COMPLETED
Conditions: Open-angle Glaucoma|Ocular Hypertension
Interventions: DRUG: Travoprost 0.004% / Timolol maleate 0.5%|DRUG: Travoprost 0.004% / Timolol maleate 0.5%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Palliative Care in Improving Quality of Life in Patients With Newly Diagnosed Pancreatic Cancer
Status: COMPLETED
Conditions: Stage IIA Pancreatic Cancer|Stage IIB Pancreatic Cancer|Stage III Pancreatic Cancer|Stage IV Pancreatic Cancer
Interventions: PROCEDURE: Psychosocial Assessment and Care|OTHER: Palliative Therapy|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Clinical Trial to Investigate Safety/Tolerability and Pharmacokinetics of DA-1229_01(Evogliptin/Metformin XR 2.5/500 mg x 2 Tablets) Compared to Co-administration of Evogliptin 5 mg and Metformin XR 1000 mg in Healthy Male Volunteers
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: DA-1229_01|DRUG: E+M
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Airway Management During Deep Sedation in Hysteroscopy
Status: NOT_YET_RECRUITING
Conditions: Deep Sedation
Interventions: PROCEDURE: face mask ventilation|PROCEDURE: nasopharyngeal tube ventilation|DEVICE: oxygen saturation monitoring|DEVICE: oxygen reserve index monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Repeat Dosing of Psilocybin in Migraine Headache
Status: COMPLETED
Conditions: Migraine Headache
Interventions: DRUG: Psilocybin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Esophageal Sparing Intensity-modulated Radiation Therapy (IMRT) for Locally-Advanced Thoracic Malignancies
Status: COMPLETED
Conditions: Non Small Cell Lung Cancer|Small Cell Lung Cancer|Thymoma|Thymus Neoplasms
Interventions: RADIATION: Esophageal sparing IMRT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of Arousal on Motor Learning, Memory and Motor Imagery Ability in Young Population
Status: COMPLETED
Conditions: Arousal
Interventions: OTHER: Low Arousal|OTHER: Medium arousal|OTHER: High arousal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy of Combination Taping Technique vs Ankle Foot Orthosis on Improving Gait Parameters in Cerebral Palsy
Status: COMPLETED
Conditions: Gait|Spastic Diplegia
Interventions: OTHER: Conventional physical therapy|OTHER: Ankle Foot Orthosis|OTHER: Combination Taping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Instrumental and Manual Increase of Couch in Neuromuscular Patients
Status: COMPLETED
Conditions: Neuromuscular Disease|Chronic Respiratory Failure|Coughing
Interventions: DEVICE: Alpha 200®|DEVICE: Alpha 200® + physiotherapist|DEVICE: Cough Assist®|DEVICE: Cough Assist® + physiotherapist|OTHER: physiotherapist
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Extended-release Naltrexone and Care Management for Alcohol Dependent Frequent Emergency Department Users
Status: COMPLETED
Conditions: Alcohol Dependence|Alcohol Use Disorder
Interventions: DRUG: XR-NTX+CM (Extended-Release Naltrexone plus Care Management)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Blood Purification in Septic Children
Status: NOT_YET_RECRUITING
Conditions: Sepsis|Blood Purification
Interventions: DEVICE: blood purification(CVVH)|DEVICE: blood purification(TPE+CVVH)|DEVICE: blood purification(HP+CVVH)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Relative Bioavailability Study of Naproxen Delayed-Release Tablets (375 mg)
Status: COMPLETED
Conditions: Rheumatoid Arthritis|Osteoarthritis
Interventions: DRUG: Naproxen Delayed Release Tables, 375 (Gevena Pharmaceuticals, Inc.)|DRUG: Naproxen (EC-Narosyn) Delayed Release Tables, 375 (Syntex (USA), Inc.)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Influence of Light Exposure on Exercise Performance Dependent on Chronotype.
Status: COMPLETED
Conditions: Endurance Performance|Reaction Time|Muscle Strength
Interventions: OTHER: exposure to normal light|OTHER: exposure to bright light|OTHER: exposure to blue-enriched light
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Double-blind, Placebocontrolled A Randomized Trial on the Efficacy of Herbal Galactogogues
Status: UNKNOWN
Conditions: Breastfeeding
Interventions: DIETARY_SUPPLEMENT: Herbal galactagogue|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ACT to Reduce Morbidity and Mortality in Hematopoietic Stem Cell Transplant (HCT) Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Hematopoietic Steam Cell Transplantation (HCT)
Interventions: BEHAVIORAL: Acceptance and Commitment Therapy (ACT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Molecular and Immunohistochemical Profiling of Tumors in Patients With Parathyroid Tumors
Status: RECRUITING
Conditions: Parathyroid Gland Adenoma|Parathyroid Gland Atypical Adenoma|Parathyroid Gland Carcinoma|Primary Hyperparathyroidism
Interventions: PROCEDURE: Biospecimen Collection|OTHER: Laboratory Biomarker Analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase 1 Study Evaluating Safety and Tolerability of NVN1000 Gel
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: NVN1000 4% Gel|DRUG: Vehicle Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Use of the Unstable Shoes in Lower Limb Lymphedema.
Status: COMPLETED
Conditions: Lower Limb Lymphedema
Interventions: OTHER: To compare the efficacy of unstable shoes with that of conventional sports shoes in people with lower-limb primary and secondary lymphedema.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Individualizing tDCS Dose
Status: RECRUITING
Conditions: tDCS|Motor Function
Interventions: DEVICE: Sham transcranial direct current stimulation|DEVICE: Individualized transcranial direct current stimulation|DEVICE: 2mA transcranial direct current stimulation|DEVICE: 4mA transcranial direct current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Reducing Symptoms of Multiple Sclerosis Using Non-invasive Neuromodulation
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DEVICE: Portable Neuromodulation Stimulator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Esomeprazole in Treatment of Early Onset Preeclampsia (ESOPE Trial)
Status: COMPLETED
Conditions: Preeclampsia
Interventions: DRUG: Esomeprazole 40 mg Oral Tablet|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Strategy to Improve Implementation of LTVV for Patients w/ ARDS
Status: WITHDRAWN
Conditions: Acute Respiratory Distress Syndrome
Interventions: BEHAVIORAL: Multi-component LTVV implementation strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Peg-Intron/Ribavirin in G 1 HCV for Non-Extended Versus 24 Week Extended Treatment After 24 Weeks (Study P04144)(COMPLETED)
Status: COMPLETED
Conditions: Hepatitis C, Chronic
Interventions: BIOLOGICAL: PegIntron (peginterferon alfa-2b; SCH 54031)|BIOLOGICAL: PegIntron (peginterferon alfa-2b; SCH 54031)|DRUG: Ribavirin|DRUG: Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Cognitive Intervention Therapy on Postoperative Delirium
Status: NOT_YET_RECRUITING
Conditions: Spinal Stenosis|Disc Herniation|Lung Neoplasms|Carcinoma, Hepatocellular
Interventions: PROCEDURE: control group|PROCEDURE: intervention group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Nivolumab With Vismodegib in Patients With Basal Cell Nevus Syndrome
Status: WITHDRAWN
Conditions: Basal Cell Nevus Syndrome
Interventions: DRUG: Vismodegib|DRUG: Nivolumab|DRUG: Ipilimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Valproate as First Line Therapy in Combination With Rituximab and CHOP in Diffuse Large B-cell Lymphoma
Status: COMPLETED
Conditions: Diffuse Large B-cell Lymphoma
Interventions: DRUG: Valproate|DRUG: Rituximab|DRUG: Cyclophosphamide|DRUG: Doxorubicin|DRUG: Vincristine|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Panitumumab-Capecitabine-Oxaliplatin In Wild-Type K-Ras Metastatic Colorectal Cancer Patients
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: panitumumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: My Interprofessional Care Team for Adherence and Research Engagement Disparities
Status: RECRUITING
Conditions: Medication Adherence|Hypertension
Interventions: BEHAVIORAL: My Interprofessional Care team for Adherence and Research Engagement (MI-CARE)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Effect of Cataract Extraction on the Contractility of Ciliary Muscle
Status: UNKNOWN
Conditions: Presbyopia|Cataract
Interventions: OTHER: UBM with pilocarpine in presbyopia
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of SGR-2921 in Relapsed/Refractory Acute Myeloid Leukemia or Myelodysplastic Syndrome
Status: RECRUITING
Conditions: Acute Myeloid Leukemia|High-Risk and Very High-Risk Myelodysplastic Syndromes
Interventions: DRUG: SGR-2921
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Use of Tranexamic Acid (TXA) in Total Joint Arthroplasty
Status: TERMINATED
Conditions: Blood Loss
Interventions: DRUG: Intravenous Placebo|DRUG: Intravenous Tranexamic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The SURGICEL® Powder Mild or Moderate Parenchymal or Soft Tissue Intraoperative Bleeding (China Study)
Status: COMPLETED
Conditions: Hemorrhage
Interventions: DEVICE: SURGICEL Powder|DEVICE: SURGICEL Original
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study to Learn More About the Safety of Drug Jivi Over a Long Period of Time in Previously Treated Patients With Hemophilia A (Bleeding Disorder Resulting From a Lack of FVIII) Who Are Receiving Jivi Regularly at Their Treating Doctors to Prevent Bleeding
Status: ACTIVE_NOT_RECRUITING
Conditions: Hemophilia A
Interventions: DRUG: Damoctocog alfa pegol (Jivi, BAY94-9027)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety of Pyronaridine-artesunate for the Treatment in Uncomplicated Falciparum Malaria
Status: COMPLETED
Conditions: Malaria, Falciparum
Interventions: DRUG: Pyronaridine-artesunate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Support for Physical Activity in Everyday Life With Parkinson's Disease
Status: RECRUITING
Conditions: Parkinson Disease|Physical Activity|eHealth|Gait Disorders, Neurologic
Interventions: BEHAVIORAL: Motor-cognitive home exercise supported by eHealth technology|BEHAVIORAL: Individualized home exercise program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of Peg-interferon Plus Epoetin-alfa for Treatment of Chronic Hepatitis C Virus Infection
Status: COMPLETED
Conditions: Hepatitis C
Interventions: DRUG: Peginterferon-alpha-2b (PEG-Intron)|DRUG: Ribavirin|DRUG: Epoetin-alpha (Procrit)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: S0353, Gemcitabine in Treating Patients With Recurrent Bladder Cancer That Has Not Responded to Previous Bacillus Calmette-Guerin
Status: COMPLETED
Conditions: Bladder Cancer
Interventions: DRUG: gemcitabine hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating BLI-489 and Piperacillin in Healthy Subjects
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: BLI-489/Piperacillin|DRUG: BLI-489|DRUG: Piperacillin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Glossopharyngeal Nerve Blockade for Awake Videolaryngoscope Assisted Endotracheal Intubation in the Morbidly Obese
Status: UNKNOWN
Conditions: Gagging
Interventions: OTHER: lidocaine|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Expressing Personal Recollections in English or Spanish to Alleviate Traumatic Emotions (Exprésate)
Status: COMPLETED
Conditions: Post Traumatic Stress Disorder
Interventions: BEHAVIORAL: Weekly Emotional Disclosure (WED)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Intraoperative Indocyanine Green Fluorescence Angiography in Colorectal Surgery to Prevent Anastomotic Leakage
Status: RECRUITING
Conditions: Colorectal Cancer
Interventions: DRUG: FLUO+ : Intraoperative fluorescence angiography (IOFA) with indocyanine green (ICG).
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: First in Human Study of ANXV (Recombinant Human Annexin A5) in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: BIOLOGICAL: ANXV|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Safety and Efficacy of EBV Specific T-cell Lines
Status: RECRUITING
Conditions: Epstein-Barr Virus Infections|Post-Transplant Lymphoproliferative Disorder|Lymphoma
Interventions: BIOLOGICAL: Group A|BIOLOGICAL: Group B
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Lycopene in the Treatment of Erosive Oral Lichen Planus
Status: COMPLETED
Conditions: Erosive Lichen Planus
Interventions: DRUG: Lycopene Softgel, 10 Mg|DRUG: Prednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Safety and Efficacy of Oral Armour Thyroid Compared to Synthetic T4 for the Treatment of Primary Hypothyroidism in Adult Participants
Status: RECRUITING
Conditions: Hypothyroidism
Interventions: DRUG: Armour Thyroid|DRUG: Levothyroxine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: TAB014 Compared to Lucentis® in Patients With Neovascular Age-related Macular Degeneration
Status: RECRUITING
Conditions: Neovascular Age-related Macular Degeneration
Interventions: DRUG: TAB014 Monoclonal Antibody Injection|DRUG: Ranibizumab Injection [Lucentis]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lateral Retinacular Release in Total Knee Arthroplasty With Patellar Replacement
Status: COMPLETED
Conditions: Anterior Knee Pain Syndrome
Interventions: PROCEDURE: Lateral retinacular release
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Different Patterns of Target Delineation in SBRT for Locally Advanced Pancreatic Cancer
Status: RECRUITING
Conditions: Treatment
Interventions: RADIATION: SBRT|DRUG: Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Outcomes of Massive Rotator Cuff Tendon Tear Treatment.
Status: NOT_YET_RECRUITING
Conditions: Rotator Cuff Tears|Rotator Cuff Syndrome
Interventions: PROCEDURE: Arthroscopic rotator cuff partial repair with superior capsular augmentation with LHBBT|PROCEDURE: Arthroscopic rotator cuff partial repair|PROCEDURE: Arthroscopic complete rotator cuff repair|DEVICE: Suture anchor(s)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Therapist Change on Dropout in a Naturalistic Sample of Inpatients With Borderline Pathology Receiving DBT
Status: COMPLETED
Conditions: Borderline Personality Disorder|PostTraumatic Stress Disorder|Psychotherapy|Dropout
Interventions: BEHAVIORAL: Dialectical Behavior Therapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Allogeneic Neuroblastoma Cells for Relapsed/ Refractory Neuroblastoma, CYCHEALL
Status: COMPLETED
Conditions: Neuroblastoma
Interventions: BIOLOGICAL: Injection of allogeneic neuroblastoma cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Blood Pressure on Cerebral Perfusion During Vascular Surgery
Status: WITHDRAWN
Conditions: Anesthesia|Peripheral Arterial Diseases
Interventions: OTHER: MAP maintained at 80 mmHg|OTHER: MAP maintained at 60 mmHg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Acute Kidney Injury in Patients Undergoing Contrast Exposure: VQ vs. CT
Status: TERMINATED
Conditions: Acute Kidney Injury|Pulmonary Embolism|Contrast-induced Nephropathy
Interventions: DIAGNOSTIC_TEST: V/Q imaging|DIAGNOSTIC_TEST: Computed tomography scan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: ADI-PEG20, Obesity and Prediabetes
Status: NOT_YET_RECRUITING
Conditions: Obesity|PreDiabetes
Interventions: BIOLOGICAL: ADI-PEG20|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective Registry of Pacemaker Patients Concerning Percentage of Right Ventricular Pacing, LVEF and NYHA Class
Status: COMPLETED
Conditions: Atrial Fibrillation|Bradycardia|Heart Block|Sick Sinus Syndrome
Interventions: DEVICE: Any pacemaker with right ventricular pacing option
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Arterial Embolism After Catheter Ablation of Atrial Fibrillation. ATRIAL FIBRILLATION
Status: RECRUITING
Conditions: Arrhythmia|Atrial Fibrillation|Ablation|Stroke, Acute|Stroke Sequelae|Embolism
Interventions: OTHER: No intervention.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Apremilast Safety and PK Study in Recalcitrant Plaque Psoriasis
Status: COMPLETED
Conditions: Psoriasis-Type Psoriasis|Plaque-Type Psoriasis
Interventions: DRUG: Apremilast
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Dexamethasone Administration on Jaundice Following Liver Resection
Status: COMPLETED
Conditions: Liver Dysfunction|Hepatectomy|Bilirubinaemia|Jaundice
Interventions: DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Mindfulness Meditation or Survivorship Education in Improving Behavioral Symptoms in Younger Stage 0-III Breast Cancer Survivors (Pathways to Wellness)
Status: UNKNOWN
Conditions: Cancer Survivor|Early-Stage Breast Carcinoma|Stage 0 Breast Cancer|Stage IA Breast Cancer|Stage IB Breast Cancer|Stage IIA Breast Cancer|Stage IIB Breast Cancer|Stage IIIA Breast Cancer|Stage IIIB Breast Cancer|Stage IIIC Breast Cancer
Interventions: OTHER: Educational Intervention|OTHER: Laboratory Biomarker Analysis|PROCEDURE: Meditation Therapy|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparing Long-acting Insulins During Exercise in Type 1 Diabetes
Status: UNKNOWN
Conditions: Diabetes Mellitus, Type 1
Interventions: DRUG: Insulin glargine|DRUG: Insulin detemir
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Myeloid-Derived Supressor Cells in Cardiac Surgery Patients
Status: COMPLETED
Conditions: Insufficiency; Cardiac, Complicating Surgery|Systemic Inflammatory Response Syndrome
Interventions: DEVICE: minimal extracorporeal circulation (MEC)|PROCEDURE: The cytokines modulations
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effects of Focal Extracorporeal Shock Wave Therapy in the Treatment of Temporomandibular Disorders of Muscular Origin
Status: RECRUITING
Conditions: Temporomandibular Joint Disorders|Extracorporeal Shockwave Therapy
Interventions: DEVICE: Focused Extracorporeal Shockwave Therapy|DEVICE: Placebo Focused Extracorporeal Shockwave Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Aromatase Plus GnRH Analogue Versus GnRH Analog Alone in Adenomyosis
Status: ACTIVE_NOT_RECRUITING
Conditions: Uterine Adenomyosis|Recurrent Implantation Failure|Menstrual Pain
Interventions: DRUG: GnRH analog (11.25mg Leuprolide acetate)|DRUG: Aromatase inhibitor and GnRH analog|DRUG: Aromatase and GnRH analog (11.25mg Leuprolide acetate)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Evidence-Based Interventions to Enhance Outcomes Among Struggling Readers
Status: COMPLETED
Conditions: Reading Disability|Anxiety
Interventions: OTHER: Reading|BEHAVIORAL: Anxiety Management|OTHER: Classroom Business as Usual|OTHER: Attention Control (math practice)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Impact on Disease Relapse of HPV Vaccination in Women Treated With LEEP for Cervical Intraepithelial Neoplasia. HOPE9
Status: NOT_YET_RECRUITING
Conditions: Cervical Intraepithelial Neoplasia
Interventions: BIOLOGICAL: Gardasil-9|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Pilot Testing of a Structural Racism Intervention for Immigrant Latinx Families
Status: RECRUITING
Conditions: Stress, Psychological|Mental Health Wellness
Interventions: BEHAVIORAL: Familias Inmigrantes Empoderándose contra eStrés Tomando Acción (FIESTA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: An Open-label Safety, Pharmacokinetic, and Efficacy Study of Miglustat for the Treatment of CLN3 Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Batten Disease
Interventions: DRUG: Miglustat 100Mg Oral Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Cryotherapy Combined or Not With Analgesics in Uncontrolled Painful Musculoskeletal Metastasis
Status: TERMINATED
Conditions: Musculoskeletal Pain
Interventions: OTHER: Cryotherapy + Medical analgesics|DRUG: Medical Analgesics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison Between Genicular Nerve Block Combined With (IPACK) Block Versus Adductor Canal Block
Status: RECRUITING
Conditions: Post Operative Pain
Interventions: PROCEDURE: Ultrasound guided Genicular nerve block|PROCEDURE: Interspace between the popliteal artery and the capsule of the popliteal artery and the capsule of the posterior knee|PROCEDURE: Adductor canal block|DRUG: Bupivacaine Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of Silfamin for Common Cold
Status: NOT_YET_RECRUITING
Conditions: Common Cold|Sore-throat
Interventions: DRUG: Silfamin|DRUG: Placebo tablet of Silfamin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Anti-CD19 U-CAR-T Cell Therapy for B Cell Hematologic Malignancies
Status: UNKNOWN
Conditions: B-cell Acute Lymphoblastic Leukemia|B-cell Lymphoma
Interventions: BIOLOGICAL: anti-CD19 UCAR-T cells|DRUG: Fludarabine|DRUG: Cytoxan|DRUG: Melphalan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy in Treating Patients With AIDS-Related Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: BIOLOGICAL: filgrastim|DRUG: cyclophosphamide|DRUG: etoposide|DRUG: lomustine|DRUG: procarbazine hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety, Tolerability and Efficacy in Patients With Burn(s)
Status: NOT_YET_RECRUITING
Conditions: Burns|Burn Degree Second
Interventions: DRUG: PMS-101|OTHER: Standard treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Effects Between Amlodipine and Hydrochlorothiazide in Combination With Losartan on 24-hr Central Blood Pressure in Hypertensive Patients
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Losartan 50mg/amlodipine 5mg|DRUG: Losartan 100mg/amlodipine 5mg|DRUG: Losartan 50mg/Hydrochlorothiazide 12.5mg|DRUG: Losartan 100mg/Hydrochlorothiazide 25mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dexmedetomidine Prevents Postoperative Delirium After Deep Brain Stimulation in Patients With Parkinson's Disease
Status: NOT_YET_RECRUITING
Conditions: Dexmedetomidine|Postoperative Delirium|Deep Brain Stimulation
Interventions: DRUG: Dexmedetomidine|DRUG: 0.9% saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Improving Quality of Life of Prostate Cancer Survivors With Androgen Deficiency
Status: RECRUITING
Conditions: Prostate Cancer
Interventions: DRUG: Testosterone Cypionate 100 MG/ML|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Iodobenzylguanidine Meta-I131 and Topotecan in Young Patients With Refractory or Relapsed Metastatic Neuroblastoma
Status: COMPLETED
Conditions: Neuroblastoma
Interventions: DRUG: Topotecan hydrochloride|PROCEDURE: Autologous hematopoietic stem cell transplantation|RADIATION: iobenguane I 131|RADIATION: total-body irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preconceptional Thromboprophylaxis in Recurrent PREGNANCY LOSSES Caused by Antiphospholipid Syndrome
Status: UNKNOWN
Conditions: Recurrent Pregnancy Losses|Positive Anti Phospholipid Syndrome
Interventions: DRUG: low molecular weight heparin (enoxeparine)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Correlation of Noninvasive Tear Film Function and the Optical Quality in Mild and Moderate Dry Eye
Status: UNKNOWN
Conditions: Tear Film Insufficiency|Dry Eye
Interventions: DEVICE: 0.1% sodium hyaluronate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Phase 2 Study of KH001 in Long-term Relief From Dentin Hypersensitivity
Status: NOT_YET_RECRUITING
Conditions: Dentin Hypersensitivity
Interventions: DRUG: KH001|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT