pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Paclitaxel and Estramustine in Treating Patients With Relapsed or Refractory Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: DRUG: estramustine phosphate sodium|DRUG: paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Netupitant/Palonosetron Hydrochloride and Dexamethasone With or Without Prochlorperazine or Olanzapine in Improving Chemotherapy-Induced Nausea and Vomiting in Patients With Breast Cancer
Status: COMPLETED
Conditions: Breast Carcinoma
Interventions: DRUG: Dexamethasone|OTHER: Laboratory Biomarker Analysis|DRUG: Netupitant/Palonosetron Hydrochloride|DRUG: Olanzapine|OTHER: Placebo|DRUG: Prochlorperazine|OTHER: Quality-of-Life Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Micronutrients and Antioxidants in HIV Infection
Status: COMPLETED
Conditions: HIV Infection
Interventions: DIETARY_SUPPLEMENT: Micronutrients and antioxidants|DIETARY_SUPPLEMENT: Multivitamins and minerals
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Observational Study to Deeply Phenotype Major Organs in Sickle Cell Disease After Curative Therapies
Status: RECRUITING
Conditions: Mortality in Sickle Cell|Sickle Cell Cardiopulmonary Complications|Sickle Cell Organ Damage|Sickle Cell Life Expectancy and Risk Factors for Early Death|Sickle Cell Lung Disease and Sudden Death
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Prospective Multi-Center Study on Vanguard With E1 Bearing
Status: TERMINATED
Conditions: Varus Deformity|Valgus Deformity|Posttraumatic Deformity|Osteoarthritis, Knee|Unspecified Disorder of Knee Joint
Interventions: DEVICE: Vanguard with E1 PS Bearing
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Irisin And Diabetic Nephropathy
Status: UNKNOWN
Conditions: Irisin
Interventions: DIAGNOSTIC_TEST: Laboratory tests|OTHER: Anthropometric measurements|PROCEDURE: Electrocardiogram and Fundus examination|OTHER: Estimated glomerular filtration rate (eGFR)|OTHER: Brachial index|DIAGNOSTIC_TEST: Laboratory tests|RADIATION: Abdominal ultrasound.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical Trial To Evaluate The Effect Of Valsartan On Insulin Sensitivity In Subjects With Impaired Glucose Tolerance
Status: COMPLETED
Conditions: Hypertension|Impaired Glucose Tolerance
Interventions: DRUG: valsartan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BReath Hold TecHniquEs for Radiotherapy of Esophageal Carcinoma
Status: TERMINATED
Conditions: Esophageal Cancer
Interventions: OTHER: DIBH using ABC technique|OTHER: DIBH using VC technique
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Feasibility of Disseminating a Novel Mobile Platform to Treat Depression
Status: WITHDRAWN
Conditions: Depression
Interventions: BEHAVIORAL: PRIME 1.0|BEHAVIORAL: PRIME 2.0
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Platform Clinical Study for Conquering Scleroderma
Status: RECRUITING
Conditions: Interstitial Lung Disease Due to Systemic Disease|Scleroderma
Interventions: DRUG: Amlitelimab|DRUG: BI 1015550|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hospital-based Usual cAre Versus Tele-monitoring Rehabilitation
Status: COMPLETED
Conditions: Total Knee Replacement
Interventions: DEVICE: Tele-monitored home exercise program|OTHER: Hospital-based rehabilitation program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Afferent Oropharyngeal Pharmacological and Electrical Stimulation on Swallow Response and on Activation of Human Cortex in Stroke Patients With Oropharyngeal Dysphagia
Status: COMPLETED
Conditions: Dysphagia|Aspiration|Stroke
Interventions: BEHAVIORAL: Dietary and oral hygiene recommendations|DIETARY_SUPPLEMENT: oral TRPV1 agonist|DEVICE: pharyngeal electrical stimulation|DEVICE: transcutaneous electrical stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Viral Kinetics and Liver Gene Expression in Response to Ribavirin and Peginterferon Therapy of Chronic Hepatitis C
Status: COMPLETED
Conditions: Hepatitis C, Chronic
Interventions: PROCEDURE: Liver Biopsy|DRUG: Peginterferon &amp; Ribavirin for Hepatitis C|DRUG: Pre-treatment Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Comparing Daratumumab, Lenalidomide, and Dexamethasone With Lenalidomide and Dexamethasone in Participants With Previously Untreated Multiple Myeloma
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: Daratumumab IV|DRUG: Lenalidomide|DRUG: Dexamethasone|DRUG: Daratumumab SC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Photoselective Vaporization of the Prostate With the GreenLight XPS™ Laser System vs TURP for the Treatment of BPH
Status: COMPLETED
Conditions: Benign Prostatic Hyperplasia
Interventions: DEVICE: Photoselective Vaporization of the Prostate|DEVICE: Transurethral Resection of the Prostate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nutrition Outreach and Understanding: Research In Serving Hearts Through Healthy Eating And Tailored Support
Status: RECRUITING
Conditions: Hypertension|Type2diabetes|Metabolic Syndrome|Obesity
Interventions: OTHER: Medically Tailored Meals
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Optimized Treatment Strategies for Early and Medium Stage Nasopharyngeal Carcinoma
Status: RECRUITING
Conditions: Stage II, III|Nasopharyngeal Squamous Cell Carcinoma|Induction Chemotheray|Concurrent Chemoradiotherapy|Reduce Treatment Intensity
Interventions: DRUG: Docetaxel|DRUG: Cisplatin|RADIATION: IMRT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of The Accuracy of Complete Crown 3D Superimposition Technique Relative to The Gold Standard Technique for Digital Quantification of Volumetric Soft Tissue Changes in The Esthetic Zone
Status: NOT_YET_RECRUITING
Conditions: Gingival Recession
Interventions: DIAGNOSTIC_TEST: Group I|DIAGNOSTIC_TEST: Group II
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of LY3200882 in Participants With Solid Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Solid Tumor
Interventions: DRUG: LY3200882|DRUG: LY3300054|DRUG: Gemcitabine|DRUG: nab-Paclitaxel|DRUG: Cisplatin|RADIATION: Intensity Modulated Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Double-Blind, Placebo-Controlled Study With Open-Label Follow-Up To Determine the Safety and Efficacy of r-HuEPO in AIDS Patients With Anemia Induced by Their Disease and AZT Therapy
Status: COMPLETED
Conditions: HIV Infections|Cytopenias
Interventions: DRUG: Epoetin alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Assessing the Efficacy of Micro-dosed Psilocybin on Reducing Anxiety & Depression Levels in Adults
Status: WITHDRAWN
Conditions: Anxiety and Depression
Interventions: DRUG: PSIL428|DIETARY_SUPPLEMENT: Oyster mushroom|DRUG: PSIL428
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Study of Givosiran (ALN-AS1) in Patients With Acute Intermittent Porphyria (AIP)
Status: COMPLETED
Conditions: Acute Intermittent Porphyria
Interventions: DRUG: givosiran (ALN-AS1)|DRUG: Sterile Normal Saline (0.9% NaCl)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Dose-confirmatory Bridging Study in Total Knee Replacement
Status: COMPLETED
Conditions: Venous Thromboembolism
Interventions: DRUG: Rivaroxaban (BAY59-7939)|DRUG: Rivaroxaban (BAY59-7939)|DRUG: Rivaroxaban (BAY59-7939)|DRUG: Enoxaparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Methylphenidate on Connectivity
Status: WITHDRAWN
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: DRUG: Methylphenidate|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Radiation Therapy, Chemotherapy, and Soy Isoflavones in Treating Patients With Stage IIIA-IIIB Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Adenocarcinoma of the Lung|Adenosquamous Cell Lung Cancer|Bronchoalveolar Cell Lung Cancer|Large Cell Lung Cancer|Recurrent Non-small Cell Lung Cancer|Squamous Cell Lung Cancer|Stage IIIA Non-small Cell Lung Cancer|Stage IIIB Non-small Cell Lung Cancer
Interventions: DIETARY_SUPPLEMENT: soy isoflavones|DRUG: cisplatin|DRUG: etoposide|DRUG: pemetrexed disodium|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: mHealth Intervention to Support Diabetes Medication Adherence
Status: UNKNOWN
Conditions: Diabetes Mellitus, Type 2
Interventions: DEVICE: DIABE-TEXT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: 3 Month Finasteride Challenge Test Can Significantly Improve the Performance of Screening for Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: Finasteride|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SCREENING
Clinical trial: Effectiveness of Trauma Therapy Using Prolonged Exposure for Patients With PTSD and a Comorbid Psychotic Disorder
Status: RECRUITING
Conditions: Post Traumatic Stress Disorder|PTSD|Psychosis
Interventions: BEHAVIORAL: Prolonged Exposure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Valsartan/Amlodipine in Patients With Mild to Moderate Essential Hypertension
Status: COMPLETED
Conditions: Essential Hypertension
Interventions: DRUG: Valsartan/amlodipine 160/5 mg|DRUG: Valsartan 160 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: ConfocAl endomicroSCopy bAsed Diet Trial in IBS
Status: RECRUITING
Conditions: Irritable Bowel Syndrome
Interventions: OTHER: Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II Clinical Trial of COVID-19 mRNA Vaccine in Adults Aged 18 Years and Older
Status: ACTIVE_NOT_RECRUITING
Conditions: COVID-19
Interventions: BIOLOGICAL: COVID-19 mRNA vaccine|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety, Tolerability, and PK of GT0918 (Proxalutamide) in Subjects With Metastatic Castrate Prostate Cancer
Status: COMPLETED
Conditions: Metastatic Castrate Resistant Prostate Cancer (mCRPC)
Interventions: DRUG: GT0918
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trabeculectomy With MMC Versus Ahmed Glaucoma Implant for Treatment of Pediatric Aphakic Glaucoma
Status: COMPLETED
Conditions: Pediatric Aphakic Glaucoma
Interventions: PROCEDURE: trabeculectomy with mitomycin-C
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Dantrolene in Subarachnoid Hemorrhage
Status: COMPLETED
Conditions: Subarachnoid Hemorrhage|Cerebral Vasospasm
Interventions: DRUG: Dantrolene|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II Clinical Study of Imatinib Mesylate in Patients With Malignant Gastrointestinal Stromal Tumors (Extension Study)
Status: COMPLETED
Conditions: Gastrointestinal Stromal Tumors
Interventions: DRUG: Imatinib Mesylate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Allogenic UCMSCs as Adjuvant Therapy for Severe COVID-19 Patients
Status: UNKNOWN
Conditions: Covid 19
Interventions: BIOLOGICAL: Normoxic Allogenic UCMSC|OTHER: Normal saline solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Study of NV-5138 in Adults With Treatment Resistant Depression
Status: RECRUITING
Conditions: Treatment Resistant Depression
Interventions: DRUG: NV-5138|DRUG: matched placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CArE for OAsI Study: Care Pathways and Anorectal Evaluation for OASI Associated Incontinence
Status: RECRUITING
Conditions: Obstetric Anal Sphincter Injury|Severe Perineal Trauma|Grade 3 Perineal Tear|Grade 4 Perineal Tear|Anal Incontinence|Faecal Incontinence|Urgency|Deferral Time|Pathways|Follow-up|Review|Endo-anal Ultrasound|Urogynaecology|Biofeedback
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Cochlear Implantation for Treatment of Single-sided Deafness
Status: TERMINATED
Conditions: Total Unilateral Deafness|Unilateral Partial Deafness
Interventions: DEVICE: Med-el MAESTRO Cochlear Implant with Flex 28 electrode array
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Aromatase Inhibition Versus Testosterone in Older Men With Low Testosterone: Randomized-Controlled Trial.
Status: COMPLETED
Conditions: Hypogonadism|Diabetes|Sarcopenia|Osteoporosis|Depression
Interventions: DRUG: Androgel (Testosterone Gel)|DRUG: Anastrozole (Aromatase Inhibitor)|DRUG: Placebo tablet|DRUG: Placebo gel|DIETARY_SUPPLEMENT: Calcium Cardone 500mg with vitamin D 400 IU
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Monoclonal Antibody Therapy in Treating Patients With Chronic Lymphocytic Leukemia, Lymphocytic Lymphoma, Acute Lymphoblastic Leukemia, or Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue|Nodal Marginal Zone B-cell Lymphoma|Noncontiguous Stage II Marginal Zone Lymphoma|Noncontiguous Stage II Small Lymphocytic Lymphoma|Recurrent Adult Acute Lymphoblastic Leukemia|Recurrent Adult Acute Myeloid Leukemia|Recurrent Marginal Zone Lymphoma|Recurrent Small Lymphocytic Lymphoma|Refractory Chronic Lymphocytic Leukemia|Splenic Marginal Zone Lymphoma|Stage III Marginal Zone Lymphoma|Stage III Small Lymphocytic Lymphoma|Stage IV Marginal Zone Lymphoma|Stage IV Small Lymphocytic Lymphoma
Interventions: BIOLOGICAL: apolizumab|OTHER: laboratory biomarker analysis|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multiparametric Ultrasound for the Diagnosis of Clinically Significant Prostate Cancer
Status: NOT_YET_RECRUITING
Conditions: Prostate Carcinoma
Interventions: PROCEDURE: ultiparametric Magnetic Resonance Imaging|DRUG: Perflutren lipid microsphere|PROCEDURE: Transrectal Ultrasound|PROCEDURE: Biopsy of Prostate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Anti COVID 19 Hyperimmune Intravenous Immunoglobulin (C-IVIG) Therapy for Severe COVID-19 Patients
Status: UNKNOWN
Conditions: Covid19
Interventions: BIOLOGICAL: Anti COVID 19 Intravenous Immunoglobulin (C-IVIG)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Abdominal Muscles Strengthening And Pelvic Floor Muscle Strengthening Exercises In Females With Urinary Incontinence
Status: COMPLETED
Conditions: Urinary Incontinence
Interventions: OTHER: abdominal strengthening exercises|OTHER: pelvic floor muscles strengthening exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Alternative Treatments in Acute Mountain Sickness
Status: TERMINATED
Conditions: Acute Mountain Sickness
Interventions: PROCEDURE: Osteopathic protocol for improving drainage of LCS|DEVICE: PEEP 10cmH2O|OTHER: Fake Osteopathic protocol|OTHER: PEEP-Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Minimal Residual Disease Guided Maintenance Therapy With Belantamab Mafodotin and Lenalidomide After Autologous Hematopoietic Cell Transplantation in Patients With Newly Diagnosed Multiple Myeloma
Status: RECRUITING
Conditions: Myeloma Multiple
Interventions: DRUG: Belantamab mafodotin|DRUG: Lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Postoperative Home Exercise Program After Cervical Spine Surgery
Status: COMPLETED
Conditions: Spinal Fusion|Cervical Spine Degenerative Disease
Interventions: BEHAVIORAL: Early Home Exercise Program|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 2, to Evaluating the Safety and Efficacy of Pridopidine Vs Placebo for Symptomatic Treatment in Patients With Huntington's Disease
Status: COMPLETED
Conditions: Huntington's Disease
Interventions: DRUG: Pridopidine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MDR - Comprehensive Reverse/Versa Dial Ti Glenosphere
Status: ENROLLING_BY_INVITATION
Conditions: Shoulder Pain|Shoulder Injuries|Shoulder Fractures|Shoulder Arthritis|Shoulder Disease
Interventions: DEVICE: Comprehensive Reverse Versa-Dial Titanium Glenosphere
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Non-inferiority of a Strategy of Continuing Oral Intake Compared With Fasting
Status: NOT_YET_RECRUITING
Conditions: Patient in Acute Respiratory Failure|Continuation of Oral Intake
Interventions: PROCEDURE: Strategy for continuing oral intake|PROCEDURE: Fasting strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Disorder of Circadian Clock Gene and Early Cognitive Dysfunction After General Anesthesia
Status: UNKNOWN
Conditions: Postoperative Delirium|General Anesthesia|Exosomes|Clock Gene|Circadian Rhythm Disorders
Interventions: OTHER: receiving general anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: An Extension Study to Evaluate the Long-term Efficacy and Safety of Oxabact in Patients With Primary Hyperoxaluria
Status: TERMINATED
Conditions: Hyperoxaluria, Primary
Interventions: BIOLOGICAL: Oxabact OC5 - Oxalobacter formigenes Strain HC-1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Sedative and Anxiolytic Premedication on Children Experience After General Anesthesia
Status: RECRUITING
Conditions: Anesthesia
Interventions: DRUG: Midazolam|DRUG: Dexmedetomidine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Adapted Physical Activity in Patients With Resected Pancreatic Cancer (APACaPOp PRODIGE-56 Study): a National Multicenter Randomized Controlled Phase II Trial
Status: UNKNOWN
Conditions: Pancreas Cancer|Quality of Life
Interventions: OTHER: Unsupervised APA program|OTHER: Supervised APA program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Treatment of Unstable Distal Clavicular Fractures (Neer 2b): Hook Plate vs Locking Plate
Status: UNKNOWN
Conditions: Clavicle Injuries
Interventions: DEVICE: Hook Plate|DEVICE: Locking Plate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Ultrasound-guided Deep Versus Superficial Continuous Serratus Anterior Plane Block for Pain Management in Patients With Multiple Rib Fractures
Status: COMPLETED
Conditions: Multiple Rib Fractures|Pain, Acute|Serratus Anterior Plane Block
Interventions: PROCEDURE: Ultrasound-guided continuous serratus anterior plane block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Evaluate if the Laparoscopic Administration of Cells Derived From the Fatty Tissue Can Improve the Inflammatory Stenosis in Patient With Crohn's Disease
Status: RECRUITING
Conditions: Stenosis; Bowel|Crohn Disease
Interventions: DRUG: Adipose derived allogenic mesenchymal stem cells (adAMSC)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Drug-Drug Interaction Study to Evaluate the Effect of Colestilan on the Pharmacokinetics of Single Doses of Candesartan Cilexetil in Healthy Subjects
Status: COMPLETED
Conditions: Hyperphosphatemia|Chronic Kidney Disease
Interventions: DRUG: colestilan|DRUG: candesartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Laser Interstitial Thermal Ablation and Stereotactic Radiosurgery for Patients With Spine Metastases
Status: RECRUITING
Conditions: Neoplasm Metastasis|Spinal Cord Diseases|Spinal Cord Compression|Spinal Cord Tumor|Spine Metastases
Interventions: PROCEDURE: Stereotactic Laser Ablation|RADIATION: Stereotactic Radiosurgery|DIAGNOSTIC_TEST: MRI guided laser ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Colour-By-Number Mandalas ın Children Hospitalised Due to A Chronic Disease
Status: COMPLETED
Conditions: Child, Only|Chronic Diseases in Children
Interventions: OTHER: This study aims to evaluate the effects of colour by number mandala in decreasing the stress of children hospitalized due to their chronic disease.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Supervisory Neglect, Non-Accidental Trauma, Brief Intervention, and Treatment Referral
Status: UNKNOWN
Conditions: Neglect, Child|Non-Accidental Trauma|Non-Accidental Injury to Child|Head Trauma
Interventions: BEHAVIORAL: SunBrite
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Outreach Project to Connect Underrepresented Populations to Clinical Trials at Ohio State University, CUSP2CT Project Trial
Status: RECRUITING
Conditions: Hematopoietic and Lymphoid System Neoplasm|Malignant Solid Neoplasm
Interventions: PROCEDURE: Accrual|PROCEDURE: Discussion|OTHER: Educational Activity|OTHER: Interview|OTHER: Review|OTHER: Survey Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Safety and Efficacy Study Of The Thoracic Aortic Stent Graft System Treating Aortic Dissection
Status: UNKNOWN
Conditions: Aortic Dissection
Interventions: DEVICE: The Thoracic Aortic Stent Graft System (Zylox-Tonbridge Medical Technology Co., Ltd. )
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate TRV120027 on Renal Pharmacodynamics in Patients With Heart Failure and Renal Dysfunction
Status: COMPLETED
Conditions: Heart Failure|Kidney Disease
Interventions: DRUG: TRV120027|DRUG: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: Comparison of Cosmetic and Functional Outcome of Silicone Sheeting and Micro-needling on Hypertrophic Scars
Status: UNKNOWN
Conditions: Hypertrophic Scar
Interventions: PROCEDURE: Microneedling|PROCEDURE: Percutaneous Collagen Induction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of a Nutritional Anti-Inflammatory Treatment to Steroids for Pediatric Crohn's Disease - the Molecular Basis
Status: UNKNOWN
Conditions: Crohn's Disease|Pediatric
Interventions: DRUG: MODULEN IBD (R) (specific Enteral Nutrition)|DRUG: prednisolon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Patients With Atherosclerotic Disease With Methotrexate-associated to LDL Like Nanoparticles
Status: UNKNOWN
Conditions: Atherosclerosis|Coronary Artery Disease|Inflammation
Interventions: DRUG: Methotrexate-LDE|DRUG: Placebo-LDE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Two-arm Study to Assess Efficacy and Safety of Ianalumab (VAY736) in Patients With Active Sjogren's Syndrome
Status: ACTIVE_NOT_RECRUITING
Conditions: Sjogren Syndrome
Interventions: BIOLOGICAL: VAY736|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Uterine Artery Ligation Prior to Uterine Incision in Women With Placenta Previa
Status: UNKNOWN
Conditions: Placenta Previa
Interventions: PROCEDURE: uterine artery ligation|PROCEDURE: Lower segment Cesarean section
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Combination of Sintilimab and AI (Doxorubicin, ADM/Ifosfamide, IFO) for the First Line Treatment of Select Type of Metastatic/Unresectable Soft Tissue Sarcoma
Status: UNKNOWN
Conditions: Sarcoma, Soft Tissue
Interventions: DRUG: Sintilimab|DRUG: Doxorubicin Hydrochloride|DRUG: Ifosfamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Safety, and Tolerability of JNJ-27018966 (Eluxadoline) in the Treatment of Irritable Bowel Syndrome With Diarrhea
Status: COMPLETED
Conditions: Irritable Bowel Syndrome
Interventions: DRUG: Eluxadoline|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ARX788 in Selected HER2-mutated or HER2-amplified/Overexpressed Solid Tumors (ACE-Pan Tumor-02)
Status: WITHDRAWN
Conditions: HER2 Mutation-Related Tumors|HER2 Amplified Solid Tumors
Interventions: DRUG: ARX788
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I Study of Pazopanib Alone and In Combination With Lapatinib in Japanese Patients With Solid Tumors
Status: COMPLETED
Conditions: Carcinoma, Renal Cell
Interventions: DRUG: pazopanib|DRUG: Lapatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Choline PET/CT vs. MeAIB PET/CT in Prostate Cancer
Status: WITHDRAWN
Conditions: Prostate Cancer
Interventions: DEVICE: Choline PET/CT and MeAIB PET/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Low-vision Rehabilitation Program for Low-vision Patients and Care Givers
Status: UNKNOWN
Conditions: Low Vision, One Eye, Unspecified Eye|Low Vision Blindness|Low Vision Aids
Interventions: OTHER: Low-vision rehabilitation program|OTHER: No Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Docetaxel, Carboplatin, Trastuzumab, and Lapatinib in Treating Patients With Early Stage Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: BIOLOGICAL: trastuzumab|DRUG: carboplatin|DRUG: docetaxel|DRUG: lapatinib ditosylate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Restylane Shaype Versus Juvederm Volux for Chin Augmentation
Status: ACTIVE_NOT_RECRUITING
Conditions: Chin Retrusion
Interventions: DEVICE: Restylane Shaype|DEVICE: Juvéderm Volux
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Patient Specific Instrumentation (PSI) Referencing Osteotomy Technological Transfer - a Randomized Control Trial (RCT)
Status: COMPLETED
Conditions: Osteotomy|Randomized Controlled Trial
Interventions: PROCEDURE: 3D printed patient specific metal jigs (PSI jig)|PROCEDURE: HTO with navigation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Anesthesia Induced Brain Cancer Survival (ABC Survival): A Feasibility Study
Status: RECRUITING
Conditions: Anesthesia|Brain Cancer|Survival
Interventions: DRUG: Propofol group|DRUG: Sevoflurane group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Inflammatory and Metabolic Outcomes After Obese Woman Performed High Intensity Interval Training
Status: COMPLETED
Conditions: Obesity and Metabolic Syndrome
Interventions: OTHER: CTR|OTHER: MICT|OTHER: HIIT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intensified Rituimab Prephase Before FCR in Untreated B-CLL
Status: COMPLETED
Conditions: B-cell Chronic Lymphocytic Leukemia CLL
Interventions: DRUG: Rituximab|DRUG: Rituximab|DRUG: Cyclophosphamide|DRUG: Fludarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacological Interaction Between Carvedilol and Methylenedioxymethamphetamine (MDMA)
Status: COMPLETED
Conditions: Mood Disorder|Substance-Related Disorders|Amphetamine-Related Disorders
Interventions: DRUG: 3,4-Methylenedioxymethamphetamine|DRUG: carvedilol|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of A-101 Topical Solution for the Treatment of Common Warts
Status: COMPLETED
Conditions: Common Wart
Interventions: DRUG: A-101|OTHER: vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Catheter Ablation of Drug-refractory Persistent Atrial Fibrillation With the HeartLight(TM) Laser Balloon in Comparison With Irrigated Radiofrequency Current Ablation
Status: COMPLETED
Conditions: Persistent Atrial Fibrillation
Interventions: DEVICE: HeartLight(TM) Laser Balloon|DEVICE: irrigated radiofrequency current ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Autologous Platelet Gel in Wound Healing of Coronary Artery Bypass Grafting (CABG) Patients
Status: WITHDRAWN
Conditions: Wounds|Infection
Interventions: BIOLOGICAL: autologous platelet gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Trial of Chinese Herbal Medicine in the Treatment of Upper Respiratory Tract Infections (URTIs)
Status: COMPLETED
Conditions: Acute Upper Respiratory Tract Infections
Interventions: DRUG: Jing Fang Bai Du san|DRUG: Placebo|DRUG: Ying Qiao san
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Newborn Vitamin A Supplementation in Improving Immune Function
Status: COMPLETED
Conditions: Vitamin A Deficiency
Interventions: DIETARY_SUPPLEMENT: retinyl palmitate|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: An Explorative Study of Afatinib in the Treatment of Advanced Cancer Carrying an EGFR, a HER2 or a HER3 Mutation
Status: UNKNOWN
Conditions: Cancers Harbouring an EGFR Mutation, (Excluding Non-squamous Non- Small Cell Lung Cancer, a Registered Indication), a HER2 Mutation or a HER3 Mutation
Interventions: DRUG: Afatinib|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Effect of SR57667B on 18F-Dopa PET Imaging in Patients With Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: DRUG: SR57667B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: On-Table Versus Off-Table Total Hip Arthroplasty
Status: ACTIVE_NOT_RECRUITING
Conditions: Arthroplasty, Replacement, Hip|Osteoarthritis, Hip
Interventions: PROCEDURE: Off Table Group|PROCEDURE: On Table Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multicenter Phase 2 Single-arm Proof-of-concept Trial to Assess the Efficacy and Safety of Ustekinumab in Association With Prednisone for the Treatment of Non-infectious Severe Uveitis (NISU)
Status: TERMINATED
Conditions: Patients With Newly Diagnosed Active NISU
Interventions: DRUG: prednisone and ustekinumab treatment|OTHER: Ophthalmologic examination|OTHER: Questionnaires|BIOLOGICAL: Blood samples
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of LY3848575 in Healthy Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: LY3848575|DRUG: LY3848575|DRUG: Placebo|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Long-Term Study in Patients With Amyotrophic Lateral Sclerosis (ALS)
Status: COMPLETED
Conditions: Amyotrophic Lateral Sclerosis (ALS)
Interventions: DRUG: E0302 (mecobalamin)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Follow-up Study to Evaluate the Safety of RetinoStat® in Patients With Age-Related Macular Degeneration
Status: ACTIVE_NOT_RECRUITING
Conditions: Age-Related Macular Degeneration
Interventions: DRUG: RetinoStat
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Mucolytics in Patients on Invasive Mechanical Ventilation Due to Severe Acute Respiratory Syndrome Coronavirus 2
Status: COMPLETED
Conditions: Corona Virus Infection|Pneumonia, Ventilator-Associated
Interventions: OTHER: Inhalation of N-acetylcysteine|OTHER: Inhalation of 5% sodium chloride|OTHER: Inhalation of 8,4% sodium bicarbonate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: EFFECT OF COGNITIVE BEHAVIORAL THERAPY ON DEPRESSION AND QUALITY OF LIFE IN PATIENTS WITH POST COVID-19
Status: ENROLLING_BY_INVITATION
Conditions: Post-COVID-19 Syndrome
Interventions: BEHAVIORAL: rehacom
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Manual Therapy and Inmediately Application of Plantar Orthoses
Status: COMPLETED
Conditions: Ankle Injuries and Disorders
Interventions: PROCEDURE: MWM (Mobilization with movement)|DEVICE: Plantar orthoses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Medical Mistrust Among Hispanic/Latino Gay, Bisexual and Other Men Who Have Sex With Men (HLMSM)
Status: NOT_YET_RECRUITING
Conditions: Human Immunodeficiency Virus
Interventions: BEHAVIORAL: Navigators (peer navigator) training|BEHAVIORAL: delayed-intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Alternative Prophylaxis in Female Recurrent Urinary Tract Infections
Status: RECRUITING
Conditions: Urinary Tract Infections|Urinary Tract Infection (UTI)
Interventions: DRUG: intravesical instillation with HA-CS|DRUG: intravesical instillation of sterile purified water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Influence of Physical Exercise on Cognitive Functioning of Traumatic Brain Injury Patients
Status: UNKNOWN
Conditions: Brain Injuries|Brain Diseases|Central Nervous System Diseases|Craniocerebral Trauma|Trauma, Nervous System
Interventions: BEHAVIORAL: Acute Physical Exercise|BEHAVIORAL: Stretching protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Biomarker Directed Adjuvant Chemotherapy for Resected Pancreas Cancer
Status: UNKNOWN
Conditions: Pancreas Cancer
Interventions: DRUG: gemcitabine|DRUG: 5-fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acute Effect of Photobiomodulation on Quadriceps Muscle Strength in Patients With Chronic Kidney Failure on Hemodialysis
Status: COMPLETED
Conditions: Renal Insufficiency, Chronic|Renal Dialysis
Interventions: OTHER: Photobiomodulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neuromuscular Adaptations After Training in the Muscle Belly of Triceps Surae
Status: SUSPENDED
Conditions: Electrical Stimulation
Interventions: OTHER: Voluntary exercise|OTHER: Wide pulse responder group|OTHER: Wide pulse non responder group|OTHER: Pulsed current group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Associations Between Analgesia Nociception Index and Preoperative Anxiety
Status: COMPLETED
Conditions: Anxiety|Opioid Consumption|Cesarean Section
Interventions: DEVICE: Analgesia Nociception Index (ANI) Monitor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of Andrographolides With or Without Capecitabine to Treat Colorectal Cancer
Status: TERMINATED
Conditions: Colorectal Neoplasms
Interventions: DRUG: Andrographolides|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of 400mcg Sublingual Versus 400mcg Buccal Misoprostol Following 200mg Mifepristone for Medical Abortion up to 63 Days Last Menstrual Period (LMP)
Status: COMPLETED
Conditions: Abortion, Induced
Interventions: DRUG: Misoprostol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adalimumab-psoriasis and Small Bowel Lesions
Status: COMPLETED
Conditions: Plaque Psoriasis|Crohn's Disease
Interventions: DRUG: Adalimumab|DEVICE: Capsule endoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hypertonic Saline Nasal Irrigation and Gargling (HSNIG) for Suspected COVID-19 in Pakistan
Status: UNKNOWN
Conditions: COVID-19
Interventions: OTHER: Hypertonic Saline Nasal Irrigation and Gargles (HSNIG)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: TREatment of degeNerative and Neoplastic Diseases With Rituximab
Status: UNKNOWN
Conditions: Diffuse Large B Cell Lymphoma
Interventions: BIOLOGICAL: Rituximab|BIOLOGICAL: Rituximab|BIOLOGICAL: Rituximab|BIOLOGICAL: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Adjuvant Avelumab in Merkel Cell Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Stage III Merkel Cell Carcinoma AJCC v8|Stage IIIB Merkel Cell Carcinoma AJCC v8|Stage IIIA Merkel Cell Carcinoma AJCC v8
Interventions: DRUG: Avelumab|OTHER: Peripheral Blood Collection|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Capecitabine (XELODA) With Or Without Lapatinib (GW572016) For Women With Refractory Advanced or Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: capecitabine|DRUG: lapatinib (GW572016)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Telerehabilitation-based Exercise Trainings on Gait and Balance in Parkinson's Patients
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: OTHER: Telerehabilitation Based LSVT BIG Exercise Protocol|OTHER: Telerehabilitation Based Functional Balance and Mobility Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of AEF0117 on Subjective Effects of Cannabis in CUD Subjects
Status: COMPLETED
Conditions: Marijuana Abuse
Interventions: DRUG: AEF0117|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Lymphocyte Enhancement in Gastroenteric Oncology
Status: RECRUITING
Conditions: Advanced Gastrointestinal Cancers
Interventions: DIETARY_SUPPLEMENT: EAA supplementation|OTHER: Isocaloric placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of a Dietary Supplement Rich in Nitric Oxide in Patients Diagnosed With Primary Ciliary Dyskinesia.
Status: RECRUITING
Conditions: Primary Ciliary Dyskinesia
Interventions: DIETARY_SUPPLEMENT: Beet-it Juice
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MiVacunaLA: an Intervention to Improve COVID-19 Vaccination Behaviors Among Latinos
Status: COMPLETED
Conditions: COVID-19 Pandemic
Interventions: BEHAVIORAL: mivacunaLA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION