pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Monoclonal Antibody Therapy, Chemotherapy, and Peripheral Stem Cell Transplantation in Treating Patients With Refractory Non-Hodgkin's Lymphoma
Status: UNKNOWN
Conditions: Lymphoma
Interventions: BIOLOGICAL: filgrastim|BIOLOGICAL: monoclonal antibody Lym-1|DRUG: cyclosporine|DRUG: paclitaxel|PROCEDURE: peripheral blood stem cell transplantation|RADIATION: indium In 111 monoclonal antibody Lym-1|RADIATION: yttrium Y 90 monoclonal antibody Lym-1
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Memory Reconsolidation Blockade as a Novel Intervention for Nicotine Dependence
Status: COMPLETED
Conditions: Smoking Cessation
Interventions: DRUG: Propranolol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Serplulimab Combined With Chemotherapy as Neoadjuvant Treatment for Locally Advanced Gastric Cancer or Adenocarcinoma of Esophagogastric Junction
Status: NOT_YET_RECRUITING
Conditions: Stomach Neoplasms|Immune Checkpoint Inhibitors
Interventions: DRUG: Serplulimab Combined With Chemotherapy|DRUG: Placebo combined with Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Trial of PfSPZ Vaccine in Healthy Adults to Determine Safety, Tolerability and Efficacy Against Heterologous CHMI
Status: TERMINATED
Conditions: Malaria|Malaria,Falciparum
Interventions: BIOLOGICAL: PfSPZ Vaccine|BIOLOGICAL: PfSPZ Challenge (7G8)|OTHER: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Edible Hepatitis B Vaccine Therapy in Healthy Participants Who Have Undergone Previous Vaccination
Status: WITHDRAWN
Conditions: Healthy, no Evidence of Disease
Interventions: BIOLOGICAL: hepatitis B antigen peptide|OTHER: placebo|OTHER: immunoenzyme technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Anti-CD70 CAR-T Cell Injection in Patients With CD70-positive Advanced Urologic Neoplasms
Status: RECRUITING
Conditions: CD70-positive Advanced Urologic Neoplasms
Interventions: BIOLOGICAL: Anti-CD70 CAR-T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of the Effect of Trastuzumab and GM-CSF on Children With Recurrent Ependymoma
Status: RECRUITING
Conditions: Posterior Fossa Ependymoma (PFEPN)
Interventions: DRUG: Trastuzumab after SubQ GM-CSF|DRUG: Trastuzumab in combination with SubQ GM-CSF
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Paramedian CESI vs Selective Nerve Root PRF for Lower Cervical Radicular Pain
Status: COMPLETED
Conditions: Neck Pain|Cervical Radiculopathy
Interventions: PROCEDURE: Paramedian cervical epidural steroid injection|PROCEDURE: Selective nerve root pulsed radiofrequency
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Exhaled Breath Analysis by Secondary Electrospray Ionization - Mass Spectrometry in Children and Adolescents
Status: RECRUITING
Conditions: Respiratory Diseases|Neurological Disorders|Type 1 Diabetes
Interventions: DIAGNOSTIC_TEST: Real-time SESI-MS breath analysis|DIAGNOSTIC_TEST: Off-line breath analysis|DIAGNOSTIC_TEST: Blood analysis|DIAGNOSTIC_TEST: Saliva analysis|DIAGNOSTIC_TEST: Urine analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety, Tolerability, and Immunogenicity of GC3106 (Quadrivalent Cell-culture Based Influenza Vaccine)
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Quadrivalent cell-culture based influenza vaccin|BIOLOGICAL: Trivalent influenza vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of Eltrombopag + Tacrolimus in Chinese Refractory or Relapsed Aplastic Anemia Patients
Status: COMPLETED
Conditions: Aplastic Anemia|Drug Effect
Interventions: DRUG: Tacrolimus|DRUG: Placebo (for Tacrolimus)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Interleukin-2 on Active Dermatomyositis
Status: ENROLLING_BY_INVITATION
Conditions: Dermatomyositis
Interventions: DRUG: Interleukin-2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Upcoming Clinical Study to Measure the Safety and Impact of a Drug Called Macitentan in Teenage and Adult Fontan Patients.
Status: TERMINATED
Conditions: Congenital Heart Disease With Fontan Circulation
Interventions: DRUG: macitentan 10 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Sonrotoclax (BGB-11417) Plus Zanubrutinib (BGB-3111) Compared With Venetoclax Plus Obinutuzumab in Participants With Chronic Lymphocytic Leukemia (CLL)
Status: RECRUITING
Conditions: CLL
Interventions: DRUG: Sonrotoclax|DRUG: Zanubrutinib|DRUG: Venetoclax|DRUG: Obinutuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testing a Novel Data-to-Suppression (D2S) Intervention Strategy in the Ryan White HIV/AIDS Program
Status: ACTIVE_NOT_RECRUITING
Conditions: Hiv
Interventions: BEHAVIORAL: Data to Suppression (D2S)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ARCHER1050: A Study of Dacomitinib vs. Gefitinib in 1st-Line Treatment Of Advanced NSCLC.
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer With EGFR-Activating Mutations
Interventions: DRUG: Dacomitinib (PF-00299804)|DRUG: Gefitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy in Treating Patients With Advanced Cancer That is Metastatic or Cannot Be Removed By Surgery
Status: COMPLETED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: oxaliplatin|DRUG: leucovorin calcium|DRUG: fluorouracil|DRUG: capecitabine|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of 'Empathy Dress' and Exercise on Midwifery Students' Discomfort, Empathy and Compassionate Love Levels
Status: COMPLETED
Conditions: Empathy|Discomfort|Love
Interventions: BEHAVIORAL: The exercise program with the 'Empathy Dress'
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Study of Olanzapine Plus Fluoxetine in Combination for Treatment of Treatment Resistant Depression
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: Olanzapine|DRUG: Fluoxetine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Phase II Study of TS-1 Therapy and TS-1+PSK Therapy Against Advanced Gastric Carcinoma
Status: TERMINATED
Conditions: Gastric Cancer
Interventions: DRUG: Tegafur/gimeracil/oteracil potassium (S-1), Krestin (PSK)|DRUG: Tegafur/gimeracil/oteracil potassium (S-1)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CKD-330 Drug-Drug Interaction Study (Candesartan)
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Candesartan 32mg|DRUG: Candesartan 32mg/Amlodipine 10mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Integral Remediation for Major Depression ("Rehabilitación Integral Para la Depresión Mayor", RIDEM)
Status: COMPLETED
Conditions: Major Depressive Disorder|Cognitive Symptom
Interventions: BEHAVIORAL: Functional Remediation|DEVICE: Computerized Cognitive Training (CCT)|BEHAVIORAL: Psychoeducation|DEVICE: Online games
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intensive Blood Pressure and LDL Lowering in Diabetic Patients With Coronary Artery Disease
Status: COMPLETED
Conditions: Type 2 Diabetes|Coronary Artery Disease|Hypertension|Dyslipidemia
Interventions: OTHER: intensive control|OTHER: standard control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: ICCM of Common Childhood Diseases: Mozambique and Uganda
Status: COMPLETED
Conditions: Malaria|Pneumonia|Diarrhoea
Interventions: OTHER: Technology supported supervision|BEHAVIORAL: Community supported supervision|OTHER: Integrated community case management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Reversal Agent Use in Patients Treated With Direct Oral Anticoagulants or Vitamin K Antagonists (RADOA). Focus on New Antidots
Status: WITHDRAWN
Conditions: Severe Bleeding|Urgent Surgery
Interventions: PROCEDURE: Urgent surgery which can not be postponed to the next 24 hrs
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Evaluate the Effect of Multiple Doses of Isavuconazole on the Pharmacokinetics of Repaglinide and Caffeine
Status: COMPLETED
Conditions: Pharmacokinetics of Repaglinide|Pharmacokinetics of Caffeine|Healthy Subjects
Interventions: DRUG: Isavuconazole|DRUG: Repaglinide|DRUG: Caffeine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Immunogenicity, Safety and Tolerability of a Trivalent Subunit Inactivated Vaccine in Healthy Subjects 50 Years and Above
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Fluvirin(TIVf)|BIOLOGICAL: Agriflu (TIV)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Neoadjuvant Dabrafenib, Trametinib and/or Pembrolizumab in BRAF Mutant Resectable Stage III Melanoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Melanoma
Interventions: DRUG: Dabrafenib|DRUG: Trametinib|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Protective Efficacy of Genetically Attenuated PfSPZ-GA1 Vaccine in Healthy Dutch Volunteers
Status: COMPLETED
Conditions: Malaria
Interventions: BIOLOGICAL: PfSPZ-GA1 Vaccine|BIOLOGICAL: PfSPZ Vaccine|OTHER: Normal Saline|BIOLOGICAL: Mosquito-bite CHMI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effects of Gabapentin and Ramosetron on Postoperative Nausea and Vomiting in Laparoscopic Gynecological Surgery
Status: UNKNOWN
Conditions: Postoperative Nausea and Vomiting
Interventions: DRUG: Gabapentin|DRUG: Ramosetron|DRUG: Gabapentin and Ramosetron
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Effect of Pirtobrutinib (LOXO-305) on QTc Interval in Healthy Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Pirtobrutinib|DRUG: Placebo|DRUG: Moxifloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Phase IIb Safety and Efficacy Study of Different Oral Doses of BAY94-8862 in Subjects With Worsening Chronic Heart Failure and Left Ventricular Systolic Dysfunction and Either Type 2 Diabetes Mellitus With or Without Chronic Kidney Disease or Chronic Kidney Disease Alone
Status: COMPLETED
Conditions: Heart Failure
Interventions: DRUG: Finerenone (BAY94-8862)|DRUG: Placebo|DRUG: Inspra (eplerenone)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Efficacy and Safety of gpASIT+TM to Treat Seasonal Allergic Rhinoconjunctivitis
Status: COMPLETED
Conditions: Grass Pollen Allergy|Hay Fever
Interventions: BIOLOGICAL: gpASIT+TM|BIOLOGICAL: gpASIT+TM|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Perioperative Immunonutrition in Patients With Head and Neck Cancer
Status: COMPLETED
Conditions: Head and Neck Cancer|Nutrition, Healthy
Interventions: DIETARY_SUPPLEMENT: Experimental (Immunonutrition) Group|DIETARY_SUPPLEMENT: Active Comparator Group ( Standard enteral nutrition)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pilot Study of Growth Hormon to Treat SMA Typ II and III
Status: COMPLETED
Conditions: Muscular Atrophy, Spinal
Interventions: DRUG: somatotropin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Three Month Bleeding-Model Clinical Study
Status: COMPLETED
Conditions: Gingivitis
Interventions: DRUG: 0.454% stannous fluoride|DRUG: 0.76% sodium monofluorophosphate|DRUG: 0.454% stannous fluoride AM and 0.76% sodium monofluorophosphate PM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Congenital Factor VII Deficiency
Status: COMPLETED
Conditions: Congenital Bleeding Disorder|Congenital FVII Deficiency
Interventions: DRUG: activated recombinant human factor VII|DRUG: Fresh frozen plasma (Source unspecified)|DRUG: Plasma-derived FVII (LFB)|DRUG: Prothrombin Complex conc. (PCC)|DRUG: Plasma-derived FVII conc. (pdFVII Baxter)|DRUG: Plasma-derived FVII conc. (pdFVII PFL)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of the Diagnostic Accuracy of Hysterosalpingo-lidocaine-foam Sonography Versus Hysterosalpingography in Tubal Patency Assessment to the Gold Standard of Laparoscopy and Dye Testing
Status: RECRUITING
Conditions: Tubal Factor Infertility
Interventions: DIAGNOSTIC_TEST: Hysterosalpingo-lidocaine-foam-sonography combined with power doppler (HyLiFoSy-PD)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: First in Man Clinical Study to Investigate Safety, Tolerability and Pharmacokinetics of Single Ascending Doses of CM3.1-AC100
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: CM3.1-AC100|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Laser Hair Depilation Darker Skin Pilonidal Disease
Status: NOT_YET_RECRUITING
Conditions: Pilonidal Disease|Pilonidal Sinus|Pilonidal Abscess|Pilonidal Cyst/Fistula
Interventions: PROCEDURE: Laser hair depilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of an Erector Spinae Plane Block in VATS/RATS
Status: UNKNOWN
Conditions: Pain, Postoperative|Post-Op Complication
Interventions: DRUG: Erector spinae plane block with ropivacaine 3.75mg/ml
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: RN624 For Pain Of Post-Herpetic Neuralgia
Status: COMPLETED
Conditions: Neuralgia, Postherpetic
Interventions: DRUG: RN624|DRUG: RN624|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Compare the Same Dosage of Insulin Using a Combination of Cartridges, 30 Units as 2 Cartridges vs. 1 Cartridge
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Technosphere® Insulin 10U + 20U|DRUG: Technosphere® Insulin 30U
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Zinc Supplement Before or With Food in Generally Healthy Men
Status: COMPLETED
Conditions: Zinc Deficiency|Dyslipidemias|Zinc Excess|Inflammation
Interventions: DIETARY_SUPPLEMENT: Zinc supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Lipolytic Effects of GH in Human Subjects in Vivo
Status: COMPLETED
Conditions: Metabolic Diseases|Growth Hormone Treatment
Interventions: DRUG: Growth Hormone|DRUG: Pegisomant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy of Ingenol Mebutate on Actinic Keratoses and Field Cancerization vs Cryotherapy
Status: COMPLETED
Conditions: Actinic Keratosis
Interventions: DRUG: Ingenol mebutate|PROCEDURE: cryotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Therapeutic Phlebotomies on the Triglycerides Concentration in Patients With Hypertriglyceridemia and Hyperferritinemia
Status: COMPLETED
Conditions: Hyperferritinemia|Hypertriglyceridemia
Interventions: PROCEDURE: Phlebotomy|BEHAVIORAL: Dietary and lifestyle counseling.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Renal Effects of Erythropoietin in Humans
Status: COMPLETED
Conditions: Renal Effects
Interventions: DRUG: Erythropoietin (Epoetin-beta, NeoRecormon®)|DRUG: Erythropoietin (Epoetin-beta, NeoRecormon®)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Prospective Study of Detection of Sarcopenia in Clinical Practice for Patient With Ovarian or Endometrial Cancer
Status: RECRUITING
Conditions: Ovarian Neoplasms|Sarcopenia
Interventions: DIAGNOSTIC_TEST: Sarcopenia diagnostic test
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Sedation Strategy on Duration Mechanical Ventilation in Patient After Cardiac Surgery
Status: COMPLETED
Conditions: Respiratory Failure|Mechanical Ventilation Complication|Sedation Complication
Interventions: DRUG: Propofol|DRUG: Dexmedetomidine|DRUG: Propofol and dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Minimally Invasive Micro Sclerostomy (MIMS®) Inferonasal Procedure - Performance Evaluation Study
Status: COMPLETED
Conditions: This Study is Conducted Under Inclusion/ Exclusion Criteria
Interventions: DEVICE: MIMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Antibiotic Rifampin to Reduce High Levels of Blood and Urine Calcium in IIH
Status: UNKNOWN
Conditions: Idiopathic Infantile Hypercalcemia - Mild Form
Interventions: DRUG: Rifampin 150 mg, 300 mg capsules and 25 mg/mL oral suspension
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acute Psychotherapy for Bipolar II Depression
Status: COMPLETED
Conditions: Bipolar Disorder|Depression
Interventions: DRUG: IPSRT plus placebo (IPSRT-PLA)|DRUG: IPSRT plus quetiapine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Testing of the Cancer Thriving and Surviving Breast Cancer Program
Status: COMPLETED
Conditions: Breast Neoplasm|Early-Stage Breast Cancer|Self-Management|Intervention|Cancer Survivorship
Interventions: BEHAVIORAL: CTS-BC-CH
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Selective PDE9 Inhibition With IMR-687 in Adults With Heart Failure With Preserved Ejection Fraction
Status: WITHDRAWN
Conditions: Heart Failure With Preserved Ejection Fraction
Interventions: DRUG: IMR-687|OTHER: IMR-687 Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Decision Aids in Improving Knowledge in Patients With Newly Diagnosed Prostate Cancer
Status: COMPLETED
Conditions: Stage II Prostate Cancer|Stage IIA Prostate Cancer|Stage IIB Prostate Cancer|Stage III Prostate Cancer|Stage I Prostate Cancer|PSA Level Five to Ten|PSA Level Less Than Five|PSA Level Ten to Fifty
Interventions: OTHER: Internet-Based Intervention|OTHER: Internet-Based Intervention|OTHER: Best Practice|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration|OTHER: Survey Administration|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Phase I Study of the Safety of Proleukin (Aldesleukin) in Combination With Ganciclovir and Antiretroviral Therapy in HIV Seropositive Patients With Cytomegalovirus (CMV) Retinitis
Status: COMPLETED
Conditions: Cytomegalovirus Retinitis|HIV Infections
Interventions: DRUG: Aldesleukin
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: A Study of Efficacy of Treatment With Bortezomib (in Combination With Doxorubicin and Dexamethasone) in Previously Untreated Patients With Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: PAD induction
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: JS016 (Anti-SARS-CoV-2 Monoclonal Antibody)With Mild and Moderate COVID-19 or SARS-CoV-2 Asymptomatic Infection Subects
Status: COMPLETED
Conditions: COVID-19
Interventions: BIOLOGICAL: Recombinant Human Anti-SARS-CoV-2 Monoclonal Antibody(25mg/kg;50mg/kg;100mg/kg)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Swallowing, Feeding and Eating in Children Born With Oesophageal Atresia/Trache-oesophageal Fistula (OA/TOF)
Status: UNKNOWN
Conditions: Esophageal Atresia With Tracheoesophageal Fistula
Interventions: DIAGNOSTIC_TEST: high resolution impedance manometry
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical Trial NuSmile Crowns
Status: COMPLETED
Conditions: Primary Dental Caries, Multisurface Origin (Diagnosis)
Interventions: DEVICE: Nu Smile Zirconia crown|DEVICE: Nu Smile Pre Veneered crown|DEVICE: Composite strip crown
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating the Safety and Efficacy of BGC20-0582 Lice Treatment Gel for Head Lice Infestation
Status: COMPLETED
Conditions: Pediculus Humanus Capitis|Head Lice
Interventions: DRUG: Placebo|DRUG: BGC20-0582
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: AMG 172 First in Human Study in Patients With Kidney Cancer
Status: COMPLETED
Conditions: Renal Cell Adenocarcinoma|Clear Cell Renal Carcinoma|Clear Cell Renal Cell Carcinoma|Renal Cell Carcinoma
Interventions: DRUG: AMG 172
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of Perception of Patients Suffering of Knee Osteoarthritis Regarding Effectiveness of Intra-articular Injection
Status: UNKNOWN
Conditions: Knee Osteoarthritis
Interventions: PROCEDURE: Reception|DRUG: Joint injection with triamcinolone hexacetonide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Water-based Zinc Efficacy Trial in Beninese Shool Children
Status: COMPLETED
Conditions: Zinc Deficiency
Interventions: DEVICE: LSF-filtering device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Management of Retained Placenta With the "Windmill" Technique of Umbilical Cord Traction
Status: RECRUITING
Conditions: Placenta; Retention
Interventions: OTHER: Windmill at 30 Minutes|OTHER: Windmill at 45 Minutes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating the Efficacy and Safety of CKD-314 (Nafabelltan) in Hospitalized Adult Patients Diagnosed With COVID-19 Pneumonia
Status: COMPLETED
Conditions: COVID-19
Interventions: DRUG: Nafamostat Mesilate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HA-1 T TCR T Cell Immunotherapy for the Treatment of Patients With Relapsed or Refractory Acute Leukemia After Donor Stem Cell Transplant
Status: SUSPENDED
Conditions: Juvenile Myelomonocytic Leukemia|Recurrent Acute Biphenotypic Leukemia|Recurrent Acute Undifferentiated Leukemia|Recurrent Childhood Acute Lymphoblastic Leukemia|Recurrent Childhood Acute Myeloid Leukemia|Refractory Acute Lymphoblastic Leukemia|Refractory Adult Acute Lymphoblastic Leukemia|Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive|Recurrent Blastic Plasmacytoid Dendritic Cell Neoplasm|Recurrent Myelodysplastic Syndrome|Refractory Blastic Plasmacytoid Dendritic Cell Neoplasm|Refractory Myelodysplastic Syndrome|Acute Undifferentiated Leukemia|Mixed Phenotype Acute Leukemia|Recurrent Chronic Myelogenous Leukemia, BCR-ABL1 Positive|Refractory Chronic Myelogenous Leukemia, BCR-ABL1 Positive|Recurrent Acute Lymphoblastic Leukemia|Recurrent Acute Myeloid Leukemia|Myelodysplastic Syndrome|Acute Myeloid Leukemia|Acute Lymphoblastic Leukemia|Acute Biphenotypic Leukemia|Chronic Myeloid Leukemia|Chronic Myelomonocytic Leukemia|Minimal Residual Disease|Recurrent Chronic Myelomonocytic Leukemia|Recurrent Mixed Phenotype Acute Leukemia|Leukemia
Interventions: BIOLOGICAL: CD8+ and CD4+ Donor Memory T-cells-expressing HA1-Specific TCR|DRUG: Fludarabine|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility, Usability and Safety of the Vestibular Rehabilitation Using the Immersive Virtual Reality Software DizzyVR
Status: NOT_YET_RECRUITING
Conditions: Vestibular Disorder|Physical Disability
Interventions: DEVICE: DizzyVR
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Phase 2 Study of the Monoclonal Antibody MGAH22 (Margetuximab) in Patients With Relapsed or Refractory Advanced Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: BIOLOGICAL: Margetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimised CD33 (FL-33) CAR T Therapy for Refractory/Relapsed Acute Myeloid Leukaemia
Status: RECRUITING
Conditions: Refractory/Relapsed Acute Myeloid Leukaemia
Interventions: DRUG: autologous FL-33 CAR T therapy|DRUG: prior-HSCT donor-derived FL-33 CAR T therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: European/Euro-ELSO Survey on Adult and Neonatal/ Pediatric COVID-19 Patients in ECMO
Status: UNKNOWN
Conditions: COVID|SARS-CoV-2|ARDS, Human|Refractory Hypoxemia|Cardiogenic Shock|Septic Shock|Extracorporeal Membrane Oxygenation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Could the Intraoperative Radiation Exposure (Fluoroscopy) of Percutaneous Pedicle Screw Fixation be Reduced Using an Electronic Conductivity Device?
Status: UNKNOWN
Conditions: Fracture Fixation, Internal
Interventions: PROCEDURE: Spinal osteosynthesis with classical pedicle finder|PROCEDURE: Spinal osteosynthesis with pedicle finder with impedancemetry
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Perinatal Arterial Stroke Treated With Stromal Cells Intranasally
Status: COMPLETED
Conditions: Perinatal Arterial Ischemic Stroke|Neonatal Stroke
Interventions: BIOLOGICAL: Mesenchymal Stem Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultraviolet Germicidal Irradiation on the New Silicone Half-Piece Elastometric Respirators
Status: COMPLETED
Conditions: Covid19
Interventions: DEVICE: UVC Irradiation|DRUG: UVC Irradiation|DEVICE: Fit test|DEVICE: Tensile strength
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Postplacental or Delayed Insertion of the Levonorgestrel-releasing Intrauterine Device (IUD) After Vaginal Delivery
Status: COMPLETED
Conditions: Contraception
Interventions: DEVICE: Levonorgestrel-releasing IUD (Mirena)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Agaricus Blazei Murill in Patients With Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DIETARY_SUPPLEMENT: Intake of 60 ml placebo daily in addition to chemotherapy|DIETARY_SUPPLEMENT: Intake of 60 ml agaricus daily in addition to chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Autonomic Determinants of POTS - Pilot 2
Status: RECRUITING
Conditions: Postural Tachycardia Syndrome
Interventions: DRUG: Placebo oral tablet|DRUG: Moxonidine Pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Anti-diabetic Effects of Persimmon Leaf Extract
Status: COMPLETED
Conditions: Prediabetes
Interventions: DIETARY_SUPPLEMENT: Persimmon leaf extract|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Audiovisual Consultations in Prehospital Emergency Care: Randomised Controlled Trial
Status: COMPLETED
Conditions: Telemedicine|Emergency Medical Service
Interventions: DEVICE: Mandatory phone call consultation|DEVICE: Mandatory audiovisual consultation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Cediranib Maleate and Olaparib Compared to Bevacizumab in Treating Patients With Recurrent Glioblastoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Recurrent Glioblastoma
Interventions: BIOLOGICAL: Bevacizumab|DRUG: Cediranib|DRUG: Cediranib Maleate|DRUG: Olaparib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Genetic Study of Patients Suffering From Congenital Amaurosis of Leber or From an Early Severe Retinal Dystrophy
Status: COMPLETED
Conditions: Amaurosis|Retinal Diseases
Interventions: PROCEDURE: realization of a family tree|PROCEDURE: refractometry|PROCEDURE: evaluation of the presence of a nystagmus|PROCEDURE: ocular behavior|PROCEDURE: test of baby vision|PROCEDURE: test of keenness|PROCEDURE: reading test|PROCEDURE: visual field|PROCEDURE: color vision|PROCEDURE: electroretinographical activity|PROCEDURE: biomicroscopical test|PROCEDURE: retinal imaging|PROCEDURE: retinal autofluorescence|PROCEDURE: genotyping
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Multi-Center, Open-Label Long-Term Extension Study of CNM-Au8 In Patients With Stable Relapsing Multiple Sclerosis
Status: COMPLETED
Conditions: Relapsing Multiple Sclerosis
Interventions: DRUG: CNM-Au8
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Performance of Composite Coronal Build -Up in Mutilated Primary Incisors: 3 Years Results
Status: COMPLETED
Conditions: Early Childhood Caries|Pediatric Disease|Dental Caries|Dental Diseases
Interventions: OTHER: Treatment by composite coronal build-up
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Smoking Cessation on Sleep - 5
Status: COMPLETED
Conditions: Tobacco Use Cessation|Sleep Disorders
Interventions: DRUG: Bupropion|DRUG: Transdermal Nicotine Patch|DRUG: Placebo Bupropion|DRUG: Placebo transdermal nicotine patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Inhalational Anesthesia and Precipitation of Dementia: is There a Link?
Status: ACTIVE_NOT_RECRUITING
Conditions: Alzheimer's Disease|Dementia
Interventions: DRUG: Spinal anesthesia group: bupivacaine 10-15mg|DRUG: General anesthesia group: induction propofol 1.5-2mg/kg and fentanyl 1-3g/kg, maintained with isoflurane or sevoflurane|GENETIC: Blood test|OTHER: Lumbar spinal tap|BEHAVIORAL: Montreal Cognitive Assessment (MOCA) and MMSE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Femoral Extramedullary Versus Intramedullary Alignment Systems in Total Knee Arthroplasty
Status: UNKNOWN
Conditions: Knee Osteoarthritis
Interventions: PROCEDURE: Distal femoral resection in total knee arthroplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Expanded Access Study With Peginterferon Alfa-2a (Pegasys) in Participants With Chronic Myelogenous Leukemia (CML)
Status: COMPLETED
Conditions: Myelogenous Leukemia, Chronic
Interventions: DRUG: Peginterferon alfa-2a
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical and Radiographic Success Rate of Pulpotomy Versus Pulpectomy for Management of Primary Teeth With Deep Caries
Status: NOT_YET_RECRUITING
Conditions: Deep Caries
Interventions: PROCEDURE: Pulpotomy|PROCEDURE: Partial Pulpectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Lung Aeration During WEANing From Mechanical Ventilation Determined by Electrical Impedance Tomography and Lung Ultrasound
Status: UNKNOWN
Conditions: Critical Care|Weaning From Mechanical Ventilation|Electrical Impedance Tomography|End Expiratory Lung Volume|Lung Ultrasound Score
Interventions: OTHER: - Weaning from mechanical ventilation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Vilazodone to Treat Social Anxiety Disorder
Status: UNKNOWN
Conditions: Social Anxiety Disorder
Interventions: DRUG: Vilazodone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ultrasound-Guided Percutaneous Electrical Stimulation on Radial Nerve in Patients With Lateral Epicondylalgia
Status: RECRUITING
Conditions: Tennis Elbow
Interventions: OTHER: PENS plus exercise|OTHER: Sham PENS plus exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Postoperative Pain Therapy With Hydromorphone TCI-PCA vs. Morphine PCA
Status: COMPLETED
Conditions: Acute Postoperative Pain
Interventions: DRUG: Hydromorphone|DRUG: Morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Strong Futures: A Trial of Two Primary Care Based Interventions to Promote Optimal Health in Latino Infants and Toddlers
Status: COMPLETED
Conditions: Childhood Obesity|Health-Related Quality of Life
Interventions: BEHAVIORAL: Infant obesity prevention|BEHAVIORAL: Financial coaching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study to Evaluate Drug-drug Interaction Between Valopicitabine and Ribavirin
Status: COMPLETED
Conditions: Chronic Hepatitis C
Interventions: DRUG: NM283 plus Peg-IFNα-2a
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Primed vs. Unprimed rTMS in Chronic Stroke
Status: COMPLETED
Conditions: Stroke
Interventions: DEVICE: real 6-Hz primed low-frequency rTMS|DEVICE: Sham 6-Hz Primed low-frequency rTMS|DEVICE: real 1-Hz rTMS only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Measure the Meridian Energy Change of Terminal Hospice Patient Via Meridian Energy Analysis Device
Status: COMPLETED
Conditions: Hospice|Survival|Alternative Medicine|Skin Electric Conductance
Interventions: BEHAVIORAL: Infrared Lamp and Acupressure
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Hospital Versus Home Based Exercise in Patients With Chronic Stable Heart Failure
Status: COMPLETED
Conditions: Congestive Heart Failure
Interventions: BEHAVIORAL: Home-based exercise training|BEHAVIORAL: Supervised hospital-based exercise training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial in Constitutional Thinness
Status: COMPLETED
Conditions: Individuals With Constitutional Thinness
Interventions: DIETARY_SUPPLEMENT: Renutryl® Booster, an oral nutritional supplement in a 300 ml bottle (600 kcal, 30 g protein, 72 g carbohydrate, 21 g fat). One bottle per day during 14 days.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Dose Response Study of a Topical Gel for the Treatment of Raynaud's Phenomenon
Status: COMPLETED
Conditions: Raynaud's Disease|Raynaud's Disease Secondary to Scleroderma|Raynaud's Disease Secondary to Autoimmune Disease
Interventions: DRUG: MQX-503
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Intraoperative Hypotension and Perioperative Myocardial Injury
Status: COMPLETED
Conditions: Myocardial Infarction Postoperative|Myocardial Injury|Intraoperative Complications|Intraoperative Hypotension|Perioperative Complication
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Stroke Patients', Music Therapist' Engagement and Patients' Finger Movement During Music Therapeutic Interaction
Status: RECRUITING
Conditions: Hemiparesis;Poststroke/CVA
Interventions: BEHAVIORAL: Piano Learning then Free Improvisation|BEHAVIORAL: Free Improvisation then Piano Learning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic and Dose Response Study of Asfotase Alfa in Adult Patients With Pediatric-Onset Hypophosphatasia (HPP)
Status: COMPLETED
Conditions: Hypophosphatasia
Interventions: DRUG: Asfotase alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Deep Tissue Massage on Pain and Comfort After Cesarean
Status: COMPLETED
Conditions: Cesarean Section|Pain, Postoperative|Massage|Comfort|Midwifery
Interventions: OTHER: deep tissue massage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Sorafenib in Treating Patients With Advanced or Recurrent Uterine Cancer
Status: COMPLETED
Conditions: Recurrent Uterine Sarcoma|Stage III Uterine Sarcoma|Stage IV Uterine Sarcoma|Uterine Carcinosarcoma
Interventions: DRUG: sorafenib tosylate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 101-PGC-005 for the Treatment of COVID-19
Status: ACTIVE_NOT_RECRUITING
Conditions: COVID-19
Interventions: DRUG: 101-PGC-005|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Osimertinib in Patients With a Lung Cancer With Brain or Leptomeningeal Metastases With EGFR Mutation
Status: ACTIVE_NOT_RECRUITING
Conditions: Non Small Cell Lung Cancer Metastatic|Leptomeningeal Metastasis|Brain Metastases|EGFR Activating Mutation
Interventions: DRUG: Osimertinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Continuous Treatment With Rifaximin and Probiotics on the Gut Microbiota of Patients With IBS-D
Status: UNKNOWN
Conditions: IBS - Irritable Bowel Syndrome|Gut Microbiota
Interventions: DRUG: Rifaximin|DRUG: Probiotic Formula|DRUG: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Crossover Study to Evaluate the Efficacy of LED in Treating the Signs of Contact/Irritant Dermatitis of the Hand
Status: COMPLETED
Conditions: Contact Dermatitis of Hand
Interventions: DEVICE: handLITE LED device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Research Study Using Recombinant Human Insulin-Like Growth Factor-1/Recombinant Human Insulin-Like Growth Factor Binding Protein-3 for Children With Noonan Syndrome
Status: TERMINATED
Conditions: Noonan Syndrome
Interventions: DRUG: rhIGF-1/rhIGFBP-3
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Interaction Between Tipranavir and BILR 355 BS Plus Ritonavir in Healthy Male Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BILR 355 BS|DRUG: Tipranavir|DRUG: Low dose of ritonavir|DRUG: High dose of ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of Repetitive Transcranial Magnetic Stimulation (rTMS) Challenge on Cognitive and Functional Magnetic Resonance Imaging Markers in Healthy Subjects
Status: TERMINATED
Conditions: Healthy
Interventions: PROCEDURE: rTMS/Active TBS|PROCEDURE: rTMS/Placebo TBS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Gymnema Sylvestre on Metabolic Syndrome and Insulin
Status: COMPLETED
Conditions: Metabolic Syndrome
Interventions: DRUG: Placebo|DRUG: Gymnema Sylvestre
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Chemoprevention of Esophageal Squamous Cell Carcinoma (ESCC) With Aspirin and Tea Polyphenols
Status: UNKNOWN
Conditions: Carcinoma, Squamous Cell
Interventions: DRUG: Aspirin|DIETARY_SUPPLEMENT: Tea Polyphenols
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Maitland Mobilization Versus Mulligan Mobilization in Sub-Acute and Chronic Non-Specific Neck Pain
Status: UNKNOWN
Conditions: Nonspecific Neck Pain
Interventions: OTHER: mulligan mobilization|OTHER: maitland mobilization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT