pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Study of a Single Dose or Two Doses of a Quadrivalent Influenza Vaccine in Subjects Aged 6 Months or Older in India
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Quadrivalent Inactivated Influenza Vaccine (2016-2017 NH formulation), No Preservative|BIOLOGICAL: Quadrivalent Inactivated Influenza Vaccine (2016 SH formulation), No Preservative|BIOLOGICAL: Quadrivalent Inactivated Influenza Vaccine (2015-2016 NH formulation), No Preservative|BIOLOGICAL: Quadrivalent Inactivated Influenza Vaccine (2015 SH formulation), No Preservative
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Selective Digestive Decontamination in Carriers of Carbapenem-resistant Klebsiella Pneumoniae
Status: COMPLETED
Conditions: Carriage of Carbapemen-resistant Klebsialle Pneumoniae
Interventions: DRUG: Arm #1 :Oral solution and buccal gel of gentamicin and polymyxin E. Arm #2: Placebo.
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose:
Clinical trial: Evaluation of Bacterial and Fungal Contamination During Propofol Continuous Infusion
Status: UNKNOWN
Conditions: Drug Contamination
Interventions: DRUG: EDTA without re-filling|OTHER: Propofol syringe re-filling with propofol containing EDTA|OTHER: Target controlled infusion of propofol without EDTA|OTHER: Re-filling of syringe with propofol without EDTA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Reconstruction of Partial Mastectomy Defects With Pectoralis Myo-glandular Local Flap.
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: PROCEDURE: Pectoralis myo-glandular flap reconstruction.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Subtenon-injected Autologous Platelet-rich Plasma on Visual Functions in Eyes With Retinitis Pigmentosa
Status: COMPLETED
Conditions: Retinitis Pigmentosa
Interventions: BIOLOGICAL: Platelet rich plasma
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of a Pulse-based USDA-diet on Healthspan
Status: ACTIVE_NOT_RECRUITING
Conditions: Healthy Lifestyle
Interventions: OTHER: Meat based|OTHER: Pulse based
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Neurophysiological Changes After Perturbation-based Training in Older Adults
Status: RECRUITING
Conditions: Healthy Subjects|Postural Balance|Falling
Interventions: BEHAVIORAL: Perturbation-based balance training (PBT)|BEHAVIORAL: Active control (control)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Bioavailability of Different Collagen-based Treatments After Oral Intake
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DIETARY_SUPPLEMENT: Dietary supplementation with placebo.|DIETARY_SUPPLEMENT: Dietary supplementation with the collagen-based product CP1.|DIETARY_SUPPLEMENT: Dietary supplementation with the collagen-based product CP2.|DIETARY_SUPPLEMENT: Dietary supplementation with the collagen-based product CP3.|DIETARY_SUPPLEMENT: Dietary supplementation with the collagen-based product CP4.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: High-Dose Trivalent Influenza Vaccine in Inducing Immune Response Patients With Central Nervous System Tumors
Status: COMPLETED
Conditions: Central Nervous System Neoplasm
Interventions: BIOLOGICAL: trivalent influenza vaccine|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Different Types of Exercise Interventions in Patients With Type 2 Diabetes
Status: UNKNOWN
Conditions: Type 2 Diabetes
Interventions: OTHER: Aerobic endurance training intervention|OTHER: Strength endurance training intervention|OTHER: Combined aerobic endurance and strength endurance training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Resection of Colorectal Liver Metastases With or Without Routine Hilar Lymphadenectomy
Status: UNKNOWN
Conditions: Hepatic Metastases|Colorectal Cancer
Interventions: PROCEDURE: Routine hilar lymphadenectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Teen Online Problem Solving (TOPS) - An Online Intervention Following TBI
Status: COMPLETED
Conditions: TBI (Traumatic Brain Injury)|Brain Edema|Craniocerebral Trauma|Hematoma|Brain Concussion
Interventions: BEHAVIORAL: Teen Online Problem Solving
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Anterior Implant Treatment on DA, Aesthetic Perception and OHRQoL Changes
Status: COMPLETED
Conditions: Dental Anxiety|Aesthetic Perception|Oral Health-related Quality of Life
Interventions: PROCEDURE: Anterior Implant Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparing Cosmetic Outcomes: Endoscopic vs. Conventional Craniotomy for Frontal Skull Base Lesions
Status: NOT_YET_RECRUITING
Conditions: Brain Tumor
Interventions: PROCEDURE: Endoscopic Supraorbital Eyebrow Craniotomy|PROCEDURE: Conventional Frontal Craniotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Open-label Phase II Study With SUTENT in Patients Suffering From Hormone Refractory Prostate Cancer
Status: COMPLETED
Conditions: Prostatic Neoplasms|Neoplasms, Hormone-Dependent|Tumor Markers, Biological|Survival Rate|Disease-Free Survival
Interventions: DRUG: sunitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of the Addition of Bemiparin to Icodextrin Solution in Peritoneal Dialysis Patients (Bemidextrina)
Status: COMPLETED
Conditions: Peritoneal Diseases
Interventions: DRUG: bemiparin 3500 IU/day
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Self-System Therapy for Older Adults With Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer Stage III|Lung Cancer Stage IV
Interventions: BEHAVIORAL: Self-System Therapy for Older Adults with Advanced Lung Cancer (SST-LC)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: An Interactive Time-Restricted Diet Intervention (txt4fasting) for Reducing Neurocognitive Decline and Improving Survival in Patients With Brain Metastases From Breast or Lung Cancer
Status: RECRUITING
Conditions: Anatomic Stage IV Breast Cancer AJCC v8|Metastatic Breast Carcinoma|Metastatic Lung Carcinoma|Metastatic Malignant Neoplasm in the Brain|Stage IV Lung Cancer AJCC v8
Interventions: BEHAVIORAL: Behavioral Dietary Intervention|OTHER: Text Message-Based Navigation Intervention|OTHER: Internet-Based Intervention|BEHAVIORAL: Dietary Counseling and Surveillance|RADIATION: Stereotactic Radiosurgery|PROCEDURE: Biospecimen Collection|PROCEDURE: Magnetic Resonance Imaging|OTHER: Neurocognitive Assessment|OTHER: Questionnaire Administration|OTHER: Interview|OTHER: Internet-Based Intervention|RADIATION: Stereotactic Radiosurgery|OTHER: Text Message-Based Navigation Intervention|PROCEDURE: Biospecimen Collection|PROCEDURE: Magnetic Resonance Imaging|OTHER: Neurocognitive Assessment|OTHER: Questionnaire Administration|OTHER: Interview
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: SHIFTPLAN: an RCT Investigating the Effect of a Shift Work Intervention on Fatigue, Sleep and Health.
Status: UNKNOWN
Conditions: Shift-work Disorder|Insomnia|Fatigue|Mental Health Issue|Quality of Life|Coping Skills|Circadian Rhythm Disorders
Interventions: BEHAVIORAL: Education program and ergonomic schedulling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: SuRxgWell: The Use of RxWell to Minimize the Impact of Mood Disorders on the Recovery of Surgical Patients
Status: RECRUITING
Conditions: Mood Disorders|Anxiety|Depressive Symptoms|Depression|Anxiety Disorders|Anxiety Depression
Interventions: BEHAVIORAL: +RxWell|BEHAVIORAL: -RxWell
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Optimal Timing of the Initiation of Esophagogastroduodenoscopy After Oral Lidocaine Spray
Status: RECRUITING
Conditions: Blood Pressure|Tachycardia
Interventions: DRUG: Lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I Clinical Study for Evaluation of Pharmacokinetic, Safety, Tolerance of Norcantharidin Lipid Microsphere for Injection in Patients With Solid Tumor
Status: UNKNOWN
Conditions: Solid Tumor
Interventions: DRUG: Norcantharidin Lipid Microsphere for Injection|DRUG: Sodium Demethylcantharidate Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility of a Telemonitoring Program for Pregnant Women at High-Risk for Preeclampsia in Pakistan
Status: NOT_YET_RECRUITING
Conditions: Preeclampsia|Pregnant With Complication
Interventions: OTHER: Raabta Telemonitoring Program (Mobile Application)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Ranolazine Among Unrevascularized Chronic Stable Angina Patients
Status: COMPLETED
Conditions: Angina
Interventions: DRUG: Ranolazine|DRUG: Sugar pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Impact of Patient Complexity on Healthcare Utilization
Status: UNKNOWN
Conditions: Primary Care Quality Metrics|Well Child Visits in First 15 Months of Life NQF 1392|Diabetes Mellitus NQF 0059|Colorectal Cancer Screening NQF 0034|Emergency Department Utilization|Alcohol and Drug Screening
Interventions: OTHER: Charlson score and Community Social Deprivation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Chronic Pain Master Protocol (CPMP): A Study of LY3857210 in Participants With Chronic Low Back Pain
Status: COMPLETED
Conditions: Chronic Low-back Pain
Interventions: DRUG: LY3857210|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Functional Microarray-Facilitated Lidocaine Liposomal Cream Absorption for Cutaneous Anesthesia in Volunteers
Status: WITHDRAWN
Conditions: Wounds
Interventions: DEVICE: functional microarray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of 0.05% Cyclosporin Eye Drop in Stevens Johnson Syndrome Patient With Chronic Dry Eye
Status: COMPLETED
Conditions: Stevens-Johnson Syndrome
Interventions: DRUG: 0.05%cyclosporin eye drop
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of NGM120 in Subjects With Advanced Solid Tumors, Pancreatic Cancer, and Prostate Cancer Using Combination Therapy
Status: COMPLETED
Conditions: Pancreatic Cancer|Metastatic Castration-resistant Prostate Cancer|Bladder Cancer|Melanoma|Non-small Cell Lung Cancer|Colorectal Cancer|Gastric Cancer|Esophageal Cancer|Ovarian Cancer|Head Neck Squamous Cell Carcinoma|Prostate Cancer
Interventions: BIOLOGICAL: NGM120|BIOLOGICAL: NGM120|BIOLOGICAL: NGM120|BIOLOGICAL: NGM120|BIOLOGICAL: NGM120|BIOLOGICAL: NGM120|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Low Dose Radiation as Bridging Therapy in Relapsed B-Cell Non-Hodgkin Lymphoma
Status: RECRUITING
Conditions: DLBCL - Diffuse Large B Cell Lymphoma|High-grade B-cell Lymphoma|Follicular Lymphoma|Mediastinal Large B-cell Lymphoma|Indolent B-Cell Non-Hodgkin Lymphoma|Relapsed Non-Hodgkin Lymphoma|Refractory Non-Hodgkin Lymphoma
Interventions: RADIATION: Bridging radiation therapy|BIOLOGICAL: Liso-cel|RADIATION: Post-infusion radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exploration of Possible Reasons for the Discrepancy Between Expectation and Indication of Subjective Perceived Exertions
Status: COMPLETED
Conditions: Coronary Disease|Exercise Test|Physical Exertion|Cardiac Rehabilitation|Physical Therapy
Interventions: OTHER: Questionnaire, Interview|OTHER: Focus Group
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Treat Patients Whose Chronic Angina Symptoms Are Not Relieved by Medication and Have an Area of the Heart That Cannot be Treated by Standard Therapies
Status: COMPLETED
Conditions: Moderate to Severe Angina Pectoris
Interventions: GENETIC: BioBypass®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating the Mechanism of Action of PF-04965842 Monotherapy for Moderate-to-severe Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: PF-04965842 200 mg|DRUG: PF-04965842 100 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: On-line Evidence-based Positive Parenting Program for Families With Adolescents Exhibiting Mental Health Problems
Status: NOT_YET_RECRUITING
Conditions: Parenting|Wellbeing
Interventions: BEHAVIORAL: Positive parenting on-line program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Modified Vagus Nerve-preserving Laparoscopic Splenectomy and Azygoportal Disconnection
Status: COMPLETED
Conditions: Cirrhosis|Hypertension|Splenectomy|Laparoscopy
Interventions: PROCEDURE: Vagus nerve-preserving group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Perioperative FLOT vs Adjuvant XELOX for CA Stomach
Status: RECRUITING
Conditions: Cancer of Stomach, Adenocarcinoma
Interventions: DRUG: 5-FU, Leucovorin, Oxaliplatin, Docetaxel|DRUG: XELOX
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Toripalimab With Paclitaxel and Cisplatin as Neoadjuvant Treatment for Esophageal Squamous Cell Carcinoma
Status: RECRUITING
Conditions: Esophageal Squamous Cell Cancer
Interventions: DRUG: Toripalimab|DRUG: Paclitaxel|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Combination Therapy Using Li-ESWT and PDE-5 Inhibitor in Patients With Erectile Dysfunction
Status: COMPLETED
Conditions: Erectile Dysfunction
Interventions: PROCEDURE: Li-ESWT|DRUG: Tadalafil 2.5Mg Tab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Robotic Assisted Rehabilitation for Heart Failure Patients and Patients After Cardiac Surgery
Status: UNKNOWN
Conditions: Heart Failure|Post Cardiac Surgery
Interventions: DEVICE: 4 weeks robotic assisted training with the Lokomat®|DEVICE: One week robotic assisted gait training with the Lokomat®
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of α-adrenergic Receptor Antagonists on Choroid and Pupil
Status: COMPLETED
Conditions: Benign Prostatic Hyperplasia|Pupil Anomaly|Choroid Disease
Interventions: DRUG: Alfuzosin Hydrochloride 10 MG|DRUG: Tamsulosin Hydrochloride 0.4 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Cognitive Behavioral Therapy for Insomnia on Type 2 Diabetes Health Outcomes
Status: COMPLETED
Conditions: Type2 Diabetes|Insomnia
Interventions: BEHAVIORAL: Cognitive behavioral therapy for insomnia|OTHER: Health Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Relation Between TOF-Watch® SX and a Peripheral Nerve Stimulator After 4.0 mg.Kg-1 Sugammadex (P05698)
Status: COMPLETED
Conditions: Neuromuscular Blockade
Interventions: DRUG: sugammadex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gemcitabine Hydrochloride and Tanespimycin in Treating Patients With Recurrent Advanced Ovarian Epithelial or Peritoneal Cavity Cancer
Status: COMPLETED
Conditions: Primary Peritoneal Cavity Cancer|Recurrent Ovarian Epithelial Cancer|Stage III Ovarian Epithelial Cancer|Stage IV Ovarian Epithelial Cancer
Interventions: DRUG: gemcitabine hydrochloride|DRUG: tanespimycin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Community Trial to Determine Whether 'Safe Storage' Reduces Pesticide Self-poisoning in Rural Asia
Status: COMPLETED
Conditions: Pesticide Poisoning
Interventions: DEVICE: Ultraviolet light-resistant plastic in-ground pesticide storage container
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Perioperative Intravenous Lidocaine or Epidural Anesthesia on Outcomes in Complex Spine Surgery
Status: COMPLETED
Conditions: Spine Surgery
Interventions: DRUG: Lidocaine|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: TACE in Combination With PD-1/PD-L1 Inhibitors and Molecular Target Therapies for Intermediate HCC
Status: RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: PD-1/PD-L1 inhibitors+VEGF-TKI/bevacizumab|PROCEDURE: TACE
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Combination of Chemopreventive Agents (All- Trans Retinoic Acid and Tamoxifen) as Potential Treatment for the Lung Complication of COVID-19
Status: UNKNOWN
Conditions: the Lung Complication of COVID-19
Interventions: COMBINATION_PRODUCT: Aerosolized All-Trans Retinoic acid plus oral Tamoxifen|OTHER: Standard treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Cardiovascular Interactions Between Mirabegron and Tamsulosin
Status: COMPLETED
Conditions: Cardiovascular|Healthy Subjects|Pharmacokinetics
Interventions: DRUG: mirabegron|DRUG: tamsulosin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Postoperative Pain Intensity After Pulpotomy
Status: COMPLETED
Conditions: Symptomatic Irreversible Pulpitis
Interventions: COMBINATION_PRODUCT: Physiological saline|COMBINATION_PRODUCT: Hemostasis and cavity disinfection with NaOCl|DEVICE: Hemostasis and cavity disinfection with KTP laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Lenalidomide and CC-486 With Radiation Therapy in Patients With Plasmacytoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Plasmacytoma|Plasmacytoma of Bone|Multiple Myeloma
Interventions: DRUG: CC-486|DRUG: Lenalidomide|RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GLP-1 and Hypoglycemia
Status: ACTIVE_NOT_RECRUITING
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Glucagon-Like Peptide- 1 (GLP-1) infusion|OTHER: Placebo Comparator: Saline Infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effectiveness of Obstetric Lubricant Gel in Labor in Nulliparous and Primiparous Women: A Randomized Controlled Study
Status: COMPLETED
Conditions: Parturition|Obstetric; Injury Pelvic Floor
Interventions: COMBINATION_PRODUCT: Natalis Obstetric Lubrican Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Feasibility of Different Doses of Etomidate Admixed With Propofol in Induced Abortion: A Randomized, Double Blind Controlled Trial
Status: UNKNOWN
Conditions: Induced Abortion|Anesthesia
Interventions: DRUG: pentazocine|DRUG: propofol|DRUG: Etomidate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Allogeneic Stem Cell Transplantation for Advanced Neuroblastoma Using MHC Mismatched Related Donors
Status: COMPLETED
Conditions: Neuroblastoma
Interventions: DEVICE: CD34+ cells selected with the Miltenyi Clinimacs machine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: R-(-)-Gossypol Acetic Acid, Cisplatin, and Etoposide in Treating Patients With Advanced Solid Tumors or Extensive Stage Small Cell Lung Cancer
Status: COMPLETED
Conditions: Extensive Stage Small Cell Lung Cancer|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: R-(-)-gossypol acetic acid|DRUG: cisplatin|DRUG: etoposide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase IIa Study Of Men And Post-Menopausal Women With A Fractured Distal Radius
Status: TERMINATED
Conditions: Fracture Healing
Interventions: DRUG: SB-751689|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacist CVD Intervention for Patients With Inflammatory Arthritis
Status: UNKNOWN
Conditions: Inflammatory Arthritis|Cardiovascular Risk Factor|Rheumatoid Arthritis|Ankylosing Spondylitis|Psoriatic Arthritis
Interventions: OTHER: CV risk assessment and modification of global risk
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Neutropenic Fever De-escalation of Antibiotics Study
Status: NOT_YET_RECRUITING
Conditions: Hematologic Malignancy|Febrile Neutropenia|Antibiotic Stewardship
Interventions: DRUG: Cessation of antibiotics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rehabilitation and Quality of Life Assessment for Soft Tissue Sarcoma Treated With Radiotherapy and Surgery
Status: TERMINATED
Conditions: Soft Tissue Sarcoma
Interventions: OTHER: Exercise|OTHER: Enhanced Recovery after surgery|OTHER: Psychological screening with counselling services as needed|OTHER: Dietary Counseling Services
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Gong's Mobilization With and Without Stecco Fascial Therapy in Patients With Adhesive Capsulitis
Status: COMPLETED
Conditions: Adhesive Capsulitis
Interventions: OTHER: Gong's Mobilization|OTHER: Stecco Fascial Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CArdioMEtabolic Function and Reserve Capacity in Healthy Adults: The CAMERA Study
Status: RECRUITING
Conditions: Healthy
Interventions: PROCEDURE: Right Heart Catheterization with Hemodynamics and Limited Echocardiogram|PROCEDURE: Magnetic Resonance Imaging (MRI)|PROCEDURE: Dual X-ray absorptiometry (DEXA) scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Use of Vibration to Improve Visual/Spatial Neglect in Patients Affected by Stroke
Status: TERMINATED
Conditions: Unilateral Spatial Neglect
Interventions: OTHER: Vibration to upper posterior neck muscles|OTHER: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Smoking Cessation Facilitated by Glucagon-like Peptide-1 (GLP-1) Analogues
Status: COMPLETED
Conditions: Glucagon-like Peptide-1|Smoking Cessation|Weight Change, Body|Craving
Interventions: DRUG: Dulaglutide|DRUG: 0.5 ml normal saline (0.9% sodium chloride [0.9% NaCl])
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Recombinant EphB4-HSA Fusion Protein With Standard Chemotherapy Regimens in Treating Patients With Advanced or Metastatic Solid Tumors
Status: TERMINATED
Conditions: Head and Neck Squamous Cell Carcinoma|Metastatic Pancreatic Adenocarcinoma|Non-Resectable Cholangiocarcinoma|Pancreatic Adenocarcinoma|Recurrent Gallbladder Carcinoma|Recurrent Non-Small Cell Lung Carcinoma|Stage III Pancreatic Cancer|Stage IIIA Gallbladder Cancer|Stage IIIA Non-Small Cell Lung Cancer|Stage IIIB Gallbladder Cancer|Stage IIIB Non-Small Cell Lung Cancer|Stage IV Gallbladder Cancer|Stage IV Non-Small Cell Lung Cancer|Stage IV Pancreatic Cancer|Unresectable Gallbladder Carcinoma|Unresectable Pancreatic Cancer
Interventions: DRUG: Cisplatin|DRUG: Docetaxel|DRUG: Gemcitabine Hydrochloride|OTHER: Laboratory Biomarker Analysis|DRUG: Paclitaxel Albumin-Stabilized Nanoparticle Formulation|OTHER: Pharmacological Study|BIOLOGICAL: Recombinant EphB4-HSA Fusion Protein
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testing the Addition of High Dose, Targeted Radiation to the Usual Treatment for Locally-Advanced Inoperable Non-small Cell Lung Cancer
Status: RECRUITING
Conditions: Locally Advanced Lung Non-Small Cell Carcinoma|Stage IIB Lung Cancer AJCC v8|Stage III Lung Cancer AJCC v8
Interventions: DRUG: Carboplatin|DRUG: Cisplatin|PROCEDURE: Computed Tomography|BIOLOGICAL: Durvalumab|DRUG: Etoposide|RADIATION: Image Guided Radiation Therapy|DRUG: Paclitaxel|DRUG: Pemetrexed|PROCEDURE: Positron Emission Tomography|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration|RADIATION: Stereotactic Body Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Web-based Self-help Intervention Promoting Mental Health in Adolescents
Status: COMPLETED
Conditions: Mental Health|Positive Thinking|Stress|Depressive Symptoms
Interventions: BEHAVIORAL: Two-week web-based self-help intervention based on principles of positive psychology|BEHAVIORAL: Two-week web-based text messages containing fun facts
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: DS-8201a in Patients With Cancer That Tests Positive for Human Epidermal Growth Factor Receptor 2 (HER2) Protein
Status: COMPLETED
Conditions: Adenocarcinoma, Gastric|Neoplasm, Breast
Interventions: DRUG: DS-8201a
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 3 Clinical Study to Evaluate the Efficacy and Safety of Botulinum Toxin Type A for Injection (CU-20101)
Status: RECRUITING
Conditions: Moderate to Severe Glabellar Striae
Interventions: DRUG: CU-20101 treatment for Moderate to Severe Glabellar Striae
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Preventing Seroma Formation After Stripping Saphenous Vein in Coronary Bypass
Status: COMPLETED
Conditions: Coronary Bypass Graft Stenosis of Autologous Vein
Interventions: PROCEDURE: vacuum assisted closure|PROCEDURE: Axillary dissection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Piloting Conversation Cards for Adolescents
Status: TERMINATED
Conditions: Adolescent Obesity|Life Style|Health Behavior|Health Communication|Primary Health Care
Interventions: BEHAVIORAL: Conversation Cards for Adolescents and Goal-Setting|BEHAVIORAL: Goal-Setting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Diabetic Autonomic Neuropathy and Left Ventricular Function
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: DRUG: Quinapril|DRUG: Losartan|DRUG: Quinapril + Losartan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 12 Week Efficacy of Tiotropium Versus Placebo in Patients With Mild COPD According to Swedish Guidelines (SPIRIMILD)
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: tiotropium (Spiriva)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: An Open-Label, Prospective Study to Assess the Safety and Effectiveness of Adalimumab in Patients With Moderate to Severe Plaque Psoriasis in the Russian Federation
Status: COMPLETED
Conditions: Moderate to Severe Plaque Psoriasis
Interventions: BIOLOGICAL: Adalimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vasopressin and Inhaled Prostacyclin in Pediatric Pulmonary Hypertension
Status: TERMINATED
Conditions: Pulmonary Hypertension
Interventions: DRUG: Vasopressin infusion|DRUG: Vasopressin infusion and epoprostenol inhalation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GLP-1 Infusion and Long-Time Fasting
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: Glucagon-like-peptide-1 (7-36) amide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Early Changes Among FLEx, LASIK and FS-LASIK
Status: COMPLETED
Conditions: Myopia|Astigmatism
Interventions: PROCEDURE: lenticule extraction|PROCEDURE: laser in situ keratomileusis|PROCEDURE: FS assisted laser in situ keratomileusis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Structured Lifestyle Intervention on Daily Physical Activity Level in COPD
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: BEHAVIORAL: Coach, using a stepcounter with exercise counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Topical Pentoxifylline; Metformin Versus Betamethasone in the Treatment of Alopecia Areata.
Status: NOT_YET_RECRUITING
Conditions: Alopecia Areata
Interventions: DRUG: Betamethasone Valerate 0.1% Cream|DRUG: Pentoxifylline|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Three-day, In-clinic Evaluation of the BD 2nd Generation Continuous Glucose Sensor Device in Type 1 Diabetics
Status: COMPLETED
Conditions: Diabetes
Interventions: DEVICE: BD CGM with Outer Layer|DEVICE: BD CGM without Outer Layer|DEVICE: Medtronic iPro2 Professional CGM
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Safety and Immunogenicity of a Four Influenza Vaccines in Children Ages 6 Months Old to Less Than 48 Months Old
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Trivalent influenza vaccine (TIVc)|BIOLOGICAL: Trivalent influenza vaccine-licensed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Vaccine Therapy With or Without Sargramostim in Treating Patients With Advanced or Metastatic Cancer
Status: COMPLETED
Conditions: Adenocarcinoma of the Colon|Adenocarcinoma of the Gallbladder|Adenocarcinoma of the Pancreas|Adenocarcinoma of the Rectum|Adult Primary Hepatocellular Carcinoma|Advanced Adult Primary Liver Cancer|Cholangiocarcinoma of the Gallbladder|Diffuse Adenocarcinoma of the Stomach|Intestinal Adenocarcinoma of the Stomach|Male Breast Cancer|Mixed Adenocarcinoma of the Stomach|Ovarian Endometrioid Adenocarcinoma|Paget Disease of the Breast With Intraductal Carcinoma|Paget Disease of the Breast With Invasive Ductal Carcinoma|Recurrent Adult Primary Liver Cancer|Recurrent Breast Cancer|Recurrent Colon Cancer|Recurrent Gallbladder Cancer|Recurrent Gastric Cancer|Recurrent Malignant Testicular Germ Cell Tumor|Recurrent Pancreatic Cancer|Recurrent Rectal Cancer|Recurrent Salivary Gland Cancer|Salivary Gland Adenocarcinoma|Stage II Malignant Testicular Germ Cell Tumor|Stage II Pancreatic Cancer|Stage III Colon Cancer|Stage III Gastric Cancer|Stage III Malignant Testicular Germ Cell Tumor|Stage III Pancreatic Cancer|Stage III Rectal Cancer|Stage III Salivary Gland Cancer|Stage IIIA Breast Cancer|Stage IIIB Breast Cancer|Stage IV Breast Cancer|Stage IV Colon Cancer|Stage IV Gastric Cancer|Stage IV Pancreatic Cancer|Stage IV Rectal Cancer|Stage IV Salivary Gland Cancer|Thyroid Gland Medullary Carcinoma|Unresectable Gallbladder Cancer
Interventions: BIOLOGICAL: recombinant fowlpox-CEA(6D)/TRICOM vaccine|BIOLOGICAL: sargramostim|BIOLOGICAL: recombinant fowlpox GM-CSF vaccine adjuvant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lenvatinib Plus TACE Versus Sorafenib Plus TACE for HCC With PVTT
Status: UNKNOWN
Conditions: Carcinoma, Hepatocellular|Portal Vein Tumor Thrombus
Interventions: DRUG: Lenvatinib Pill|PROCEDURE: Transarterial chemoembolization(TACE)|DRUG: Sorafenib|PROCEDURE: Transarterial chemoembolization(TACE)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Establishing a Pediatric Reference Range for the 13C-Spirulina Gastric Emptying Breath Test (GEBT)
Status: RECRUITING
Conditions: Gastroparesis
Interventions: DIAGNOSTIC_TEST: 13C-Spirulina Gastric Emptying Breath Test (GEBT)|DIAGNOSTIC_TEST: 13C-Spirulina Gastric Emptying Breath Test (GEBT) - repeat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluating the Effects of Omeprazole on the Pharmacokinetics of XS004 (Dasatinib) Tablets in Healthy Adult Subjects Under Fasting Conditions
Status: COMPLETED
Conditions: Pharmacokinetics|Drug Interactions
Interventions: DRUG: Dasatinib ASD|DRUG: Omeprazole 40 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Safety and Efficacy of Different Regimens of Primaquine on Vivax Malaria Treatment in G6PD Deficient Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Vivax Malaria|G6PD Deficiency
Interventions: DRUG: Chloroquine|DRUG: Primaquine|DRUG: Primaquine|DRUG: Chloroquine|DRUG: Primaquine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Using Social Networks to Promote Physical Activity in African American and Hispanic Women
Status: ACTIVE_NOT_RECRUITING
Conditions: Cancer Prevention
Interventions: DEVICE: Activity Tracker|DEVICE: Smartphone Application|BEHAVIORAL: Questionnaires|BEHAVIORAL: Focus Group|BEHAVIORAL: Electronic Newsletters|BEHAVIORAL: Telephone Counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Trial of Lenvatinib (E7080) Plus Pembrolizumab in Participants With Selected Solid Tumors
Status: COMPLETED
Conditions: Tumors
Interventions: DRUG: Lenvatinib|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Oral Sapacitabine in Elderly Patients With Newly Diagnosed Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Sapacitabine|DRUG: Decitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Virtual Reality Rehabilitation in Patients With Total Knee Arthroplasty
Status: COMPLETED
Conditions: Total Knee Replacement|Virtual Reality Therapy|Osteoarthritis|Knee Arthroplasty|Rehabilitation
Interventions: DEVICE: Kinetec® knee continuous passive motion (CPM )|BEHAVIORAL: Functional activities|OTHER: VRRS rehabilitation|OTHER: traditional rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Short-term Effects of Thoracic Manipulation in Shoulder Impingement
Status: COMPLETED
Conditions: Shoulder Impingement Syndrome
Interventions: PROCEDURE: Shoulder impingement_TSM|PROCEDURE: Asymptomatic_TSM|PROCEDURE: Shoulder impingement_sham|PROCEDURE: Asymptomatic_sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Touching the World With a Cane: Cognitive and Neural Processes
Status: RECRUITING
Conditions: Visual Impairment|Healthy
Interventions: BEHAVIORAL: Behavioral protocol|DEVICE: EEG protocol|DEVICE: fMRI protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: CAR T Cell Receptor Immunotherapy Targeting EGFRvIII for Patients With Malignant Gliomas Expressing EGFRvIII
Status: COMPLETED
Conditions: Malignant Glioma|Glioblastoma|Brain Cancer|Gliosarcoma
Interventions: BIOLOGICAL: Epidermal growth factor receptor(EGFRv)III Chimeric antigen receptor (CAR) transduced PBL|DRUG: Aldesleukin|DRUG: Fludarabine|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Efficacy and Safety Study to Compare Three Doses of BEA 2180 BR to Tiotropium and Placebo in the Respimat Inhaler.
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: BEA 2180 BR|DRUG: Tiotropium Bromide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Pharmacokinetic (PK) Interactions Between GSK3640254 and Dolutegravir (DTG)
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: GSK3640254|DRUG: DTG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treating Binge Eating and Obesity Digitally in Black Women
Status: NOT_YET_RECRUITING
Conditions: Binge Eating|Binge-Eating Disorder|Weight Gain Prevention|Obesity
Interventions: BEHAVIORAL: Centering Appetite
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: A Randomized Prospective Trial Comparing Low-volume Bowel Preparation Methods
Status: COMPLETED
Conditions: Colorectal Cancer|Colon Adenoma
Interventions: DRUG: PEG-Asc|DRUG: SPMC 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Antibiotics vs. Placebo in Acute Uncomplicated Appendicitis
Status: ENROLLING_BY_INVITATION
Conditions: Acute Appendicitis
Interventions: DRUG: Ertapenem|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of tES Combined With Retrieval Practice on Semantic Memory in Patients With Schizophrenia
Status: NOT_YET_RECRUITING
Conditions: Schizophrenic Patients
Interventions: DEVICE: tES-tDCS group|DEVICE: tES-tACS group|DEVICE: tES-sham group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Extragonadal Effects of hCG on Calcium Homeostasis
Status: COMPLETED
Conditions: Hypogonadism|Calcium Disorder|Renal Disease
Interventions: DRUG: human chorionic gonadotropin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Dissemination of Physical Activity-related Health Competence in Vocational Education of Nursing Care
Status: ACTIVE_NOT_RECRUITING
Conditions: Physical Activity|Exercise|Education|Nursing|Competence
Interventions: BEHAVIORAL: Promotion of Physical Activity-related Health Competence (PAHCO)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of Bosentan in Sickle Cell Disease (SCD) Patients Diagnosed With Pulmonary Hypertension (PH)
Status: TERMINATED
Conditions: Pulmonary Hypertension
Interventions: DRUG: bosentan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tazarotene 0.1% Cream For the Treatment of Cutaneous T-Cell Lymphoma: A Prospective Study
Status: UNKNOWN
Conditions: Cutaneous T-Cell Lymphoma
Interventions: DRUG: Tazarotene
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Consumption of Almonds and Snack Mix Daily for 6 Months on Cognitive Function in Older Adults
Status: COMPLETED
Conditions: Mild Cognitive Impairment
Interventions: DIETARY_SUPPLEMENT: snack mix|DIETARY_SUPPLEMENT: almonds, 1.5 oz|DIETARY_SUPPLEMENT: almonds, 3 oz
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate Potential Drug Interactions Between ALXN2080 and Itraconazole, Fluconazole & Carbamazepine in Healthy Adults
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: ALXN2080|DRUG: Itraconazole|DRUG: Fluconazole (AxMP)|DRUG: Carbamazepine (AxMP)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Clinical Trial to Evaluate the Efficacy and Safety of HL301 Versus Umkamin Tab in Acute Bronchitis Patients
Status: COMPLETED
Conditions: Acute Bronchitis
Interventions: DRUG: HL301(Experimental)|DRUG: Umkamin(Active Comparator)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tolerability and Safety of IGI, 10% With rHuPH20 in PIDD
Status: COMPLETED
Conditions: Primary Immunodeficiency Diseases (PID)
Interventions: BIOLOGICAL: Immune Globulin Infusion (Human), 10%|BIOLOGICAL: Recombinant human hyaluronidase
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Safety and Efficacy of Two Steroid Treatments in the Relief of the Symptoms of Seasonal Allergic Rhinitis
Status: COMPLETED
Conditions: Seasonal Allergic Rhinitis
Interventions: DRUG: Azelastine Hydrochloride/Fluticasone Propionate Nasal Spray|DRUG: Azelastine Hydrochloride/Fluticasone Propionate Nasal Spray|DRUG: Placebo nasal spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Time to Onset of Action of 10 mg and 20 mg of Vardenafil Compared to Placebo in Males With Erectile Dysfunction
Status: COMPLETED
Conditions: Erectile Dysfunction
Interventions: DRUG: Levitra (Vardenafil, BAY38-9456)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT