pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Prophylactic Oxytocin Before Versus After Placental Delivery to Reduce Blood Loss in Vaginal Delivery
Status: UNKNOWN
Conditions: Postpartum Hemorrhage
Interventions: DRUG: oxytocin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficiency of 3D-printed Implant Versus Autograft for Orbital Reconstruction (TOR-3D)
Status: RECRUITING
Conditions: Significant Bone Defect in the Orbit
Interventions: PROCEDURE: Bone autograft|PROCEDURE: Orbital reconstruction by 3D-printed porous titanium implant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Application of SDF Verses NaF Varnish in Treatment of Carious Primary Teeth
Status: UNKNOWN
Conditions: Dental Caries in Children
Interventions: DRUG: Silver Diamine Fluoride|DRUG: Sodium Fluoride varnish
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Safety and Immunogenicity of Simultaneously Administration of EV71 Vaccine and Influenza Vaccine
Status: COMPLETED
Conditions: Enterovirus Infections|Influenza
Interventions: BIOLOGICAL: EV71 vaccine and influenza vaccine|BIOLOGICAL: EV71 vaccine|BIOLOGICAL: influenza vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study on How Semaglutide Works on Early Stages of Scar Tissue in the Liver Assessed by Pictures of the Liver
Status: COMPLETED
Conditions: Hepatobiliary Disorders|Non-alcoholic Fatty Liver Disease
Interventions: DRUG: Semaglutide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Efficacy of ATL-104 in Oral Mucositis
Status: COMPLETED
Conditions: Mucositis
Interventions: DRUG: ATL-104
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Dough Fermentation Time of Bread on the Glycaemic Index
Status: UNKNOWN
Conditions: Glycemic Index (MeSH T483740)
Interventions: OTHER: glycemic index (glucose-solution, bread samples)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Lentinula Edodes Bars on Dyslipidemia and Oxidative Stress in Cholesterol Individuals: Randomized Study
Status: COMPLETED
Conditions: Dyslipidemias
Interventions: OTHER: Shiitake cereal bar
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: INSELMA - a Randomised Controlled Trial
Status: NOT_YET_RECRUITING
Conditions: Rheumatoid Arthritis|Psoriatic Arthritis|Axial Spondyloarthritis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Cervical Cancer Screening by Self-sampling in a Cohort of Younger Women in Ethiopia
Status: RECRUITING
Conditions: Cervical Cancer|STI|Human Papilloma Virus|Microbiota
Interventions: DIAGNOSTIC_TEST: VIA (Visual Inspection with Acetic acid) and VILI (Visual Inspection with Lugol's Iodine)|DIAGNOSTIC_TEST: VIA (Visual Inspection with Acetic acid)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: STrategic Reperfusion in Elderly Patients Early After Myocardial Infarction
Status: ACTIVE_NOT_RECRUITING
Conditions: Myocardial Infarction
Interventions: DRUG: Tenecteplase|DRUG: Clopidogrel|PROCEDURE: Coronary angiography|PROCEDURE: Primary PCI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of DCC-2618 (Ripretinib) In Patients With With Advanced Gastrointestinal Stromal Tumors (GIST)
Status: COMPLETED
Conditions: Gastrointestinal Stromal Tumors
Interventions: DRUG: DCC-2618
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Investigator Initiated Open Label Study Evaluating the Efficacy and Tolerability of Oral Deucravacitinib for the Treatment of Nail Psoriasis
Status: RECRUITING
Conditions: Nail Psoriasis
Interventions: DRUG: Deucravacitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Intra-Operative Shear Wave Ultrasound Vibrometry for Characterization of Esophageal Malignant Tumors
Status: TERMINATED
Conditions: Esophageal Cancer
Interventions: DEVICE: General Electric LOGIQ E9 ultrasound system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Pilot/Pivotal Study of DBS+Rehab After Stroke
Status: RECRUITING
Conditions: Stroke|Upper Extremity Paresis
Interventions: DEVICE: Deep Brain Stimulation|OTHER: Rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study With BPI-1178 and Osimertinib in Advanced Non-small Cell Lung Cancer Patients With EGFR Mutations
Status: RECRUITING
Conditions: NSCLC
Interventions: DRUG: BPI-1178|DRUG: Osimertinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Glucose Clamp Study of Wockhardt's Insulin Human Regular for Injection and Actrapid, in Type 1 Diabetics
Status: COMPLETED
Conditions: Diabetes
Interventions: BIOLOGICAL: Wosulin R|BIOLOGICAL: Actrapid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: PROmoting Early Childhood Outside (PRO-ECO)
Status: COMPLETED
Conditions: Child Development
Interventions: BEHAVIORAL: Intervention Group - PRO-ECO Intervention|BEHAVIORAL: Wait List Group - Normal Daily Practice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Unilateral vs. Bilateral Approaches to Hybrid Stroke Rehabilitation
Status: UNKNOWN
Conditions: Stroke
Interventions: PROCEDURE: Unilateral Hybrid Intervention|PROCEDURE: Bilateral Hybrid Intervention|PROCEDURE: Robot-Assisted Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Purchasing Decisions and Food Consumption: Chile
Status: UNKNOWN
Conditions: Evaluate the Effectiveness of Taxes on Unhealthy|Evaluate the Effectiveness Subsidies for Healthy Foods
Interventions: BEHAVIORAL: Taxes|BEHAVIORAL: Subsidies|BEHAVIORAL: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Confirmatory Study of PRGN-2012 in Patients With RRP
Status: RECRUITING
Conditions: Recurrent Respiratory Papillomatosis|Papillomavirus Infection|Papillomaviridae
Interventions: DRUG: PRGN-2012
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Melatonin Osteoporosis Prevention Study
Status: COMPLETED
Conditions: Osteoporosis|Osteopenia
Interventions: DIETARY_SUPPLEMENT: melatonin|DIETARY_SUPPLEMENT: sugar pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Bioequivalency Study of Ibuprofen 200 mg and Pseudoephedrine HCL 30 mg Tablets of Dr. Reddy's Under Fasting Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Ibuprofen + Pseudoephedrine Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness and Safety of 0.5% Moxifloxacin Hydrochloride Ophthalmic Solution in Perioperative Sterilization in Patients Undergoing Ophthalmic Surgery
Status: COMPLETED
Conditions: Post Operative Endophthalmitis
Interventions: OTHER: Moxifloxacin hydrochloride ophthalmic solution
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: VA vs DA for Newly Diagnosed Hig-risk AML
Status: RECRUITING
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Venetoclax Oral Tablet|DRUG: Daunorubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Aripiprazole on Cocaine Craving and Self-Administration
Status: COMPLETED
Conditions: Cocaine Abuse
Interventions: DRUG: Aripiprazole + Cocaine|DRUG: Placebo + Cocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: IIT2020-20-SHIRAZIP-WALK: Nature Walks
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer|Cancer|Lymphoma|Leukemia|Prostate Cancer|Thyroid Cancer|Hematologic Malignancy|Non-hodgkin Lymphoma
Interventions: BEHAVIORAL: Nature based exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Anticoagulation Medicine in Surgical Repair for Total Anomalous Pulmonary Venous Connection
Status: UNKNOWN
Conditions: Total Anomalous Pulmonary Venous Connection
Interventions: DRUG: Anticoagulant Solutions|OTHER: No anticoagulant solutions|DRUG: Anticoagulant management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Irinotecan Hydrochloride and Cetuximab With or Without Ramucirumab in Treating Patients With Advanced Colorectal Cancer With Progressive Disease After Treatment With Bevacizumab-Containing Chemotherapy
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: BIOLOGICAL: cetuximab|BIOLOGICAL: ramucirumab|DRUG: irinotecan hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cervical Fixation Surgery Cervical Collar for Management of Hirayama Disease: A Randomized Study
Status: RECRUITING
Conditions: Hirayama Disease
Interventions: PROCEDURE: Posterior cervical fixation surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Selective Omission of Sentinel Lymph Node Biopsy in Mastectomy for Ductal Carcinoma in Situ: Identifying Eligible Candidates
Status: COMPLETED
Conditions: Ductal Carcinoma in Situ
Interventions: PROCEDURE: Mastectomy with sentinel lymph node biopsy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Dexamethasone and N Acetylcysteine (NAC) Versus N Acetylcysteine (NAC) Alone in the Prevention of Post Embolization Syndrome in Patients With Hepatocellular Carcinoma Following Transarterial Chemoembolization.
Status: NOT_YET_RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: N Acetylcysteine|DRUG: Dexamethasone|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Laparoscopic Occlusion of Uterine Vessels Compared to Uterine Fibroid Embolization for Treatment of Uterine Fibroids
Status: UNKNOWN
Conditions: Uterine Fibroids
Interventions: PROCEDURE: Laparoscopic bilateral occlusion of uterine artery|PROCEDURE: Radiological embolization (UFE)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Bioequivalence Study Between Telmione Plus 80/12.5mg and Micardis Plus 80/12.5 mg in Healthy Adult Volunteers
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Telmione plus 80/12.5mg|DRUG: Micardis plus 80/12.5mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Safety, Tolerability, and Immunogenicity of the MRKAd5 Gag/Pol/Nef Vaccine in Healthy Adults (V520-016)
Status: COMPLETED
Conditions: HIV-1|HIV Infections
Interventions: OTHER: Comparator: Placebo to the MRKAd5 HIV-1 gag/pol/nef vaccine|BIOLOGICAL: Monovalent MRKAd5 HIV-1 gag vaccine (1x10^9 vp/dose)|BIOLOGICAL: Trivalent MRKAd5 HIV-1 gag/pol/nef vaccine (3x10^6 vp/dose)|BIOLOGICAL: Trivalent MRKAd5 HIV-1 gag/pol/nef vaccine (3x10^7 vp/dose)|BIOLOGICAL: Trivalent MRKAd5 HIV-1 gag/pol/nef vaccine (3x10^8 vp/dose)|BIOLOGICAL: Trivalent MRKAd5 HIV-1 gag/pol/nef vaccine (3x10^9 vp/dose)|BIOLOGICAL: Trivalent MRKAd5 HIV-1 gag/pol/nef vaccine (3x10^10 vp/dose)|BIOLOGICAL: Trivalent MRKAd5 HIV-1 gag/pol/nef vaccine (1x10^11 vp/dose)|BIOLOGICAL: Comparator: Placebo to MRKAd5 HIV-1 gag vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Calot's Triangle Block for Postoperative Analgesia in Patients Undergoing Laparoscopic Cholecystectomy: a Prospective, Randomized, Double-blind, Controlled, Clinical Trial
Status: UNKNOWN
Conditions: Post-operative Pain|Gallstone Disease
Interventions: PROCEDURE: CTB group|PROCEDURE: PCIA group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Non-inferiority Study Comparing Firehawk Stent With Abbott Xience Family Stent (TARGET-AC)
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DEVICE: Firehawk™ stent system|DEVICE: Abbott Xience family Everolimus-Eluting Stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Diclofenac Potassium Versus Acetaminophen in Febrile Children With Acute Upper Respiratory Tract Infections
Status: TERMINATED
Conditions: Fever
Interventions: DRUG: Diclofenac potassium|DRUG: Acetaminophen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Adversity and Its Association With the Development and Expression of Rheumatic Diseases
Status: NOT_YET_RECRUITING
Conditions: RhA - Rheumatoid Arthritis
Interventions: OTHER: Rheumatic diseases Mistreatment Scale (RDMS)|OTHER: Routine assessment of patient index data 3 (RAPID-3)|OTHER: Health Assessment Questionnaire (HAQ)|OTHER: WHOQOL-BREF|OTHER: Depression, Anxiety and Stress Scale (DASS-21)|OTHER: Brief Resilient Coping Scale|GENETIC: Expression of CDKN2A /p16INK4a|OTHER: Immunophenotype of leukocyte subpopulations|GENETIC: Telomere length|OTHER: Cellular senescence
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Hypomagnesemia and Its Association With Calcineurin Inhibitors Use in Renal Transplant Recipients
Status: COMPLETED
Conditions: Renal Transplantation; Complication
Interventions: DIAGNOSTIC_TEST: serum magnesium level, FEMg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of Amivantamab and Lazertinib Combination Therapy Versus Osimertinib in Locally Advanced or Metastatic Non-Small Cell Lung Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: Amivantamab|DRUG: Osimertinib|DRUG: Lazertinib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Impact of Giving a Massage
Status: COMPLETED
Conditions: Mental State, Reported as Depression, Anxiety or Stress
Interventions: BEHAVIORAL: Give a massage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Trial on Safety and Pharmacokinetics of Intravaginal Curcumin
Status: COMPLETED
Conditions: Uterine Cervical Dysplasia
Interventions: DRUG: Curcumin|DRUG: curcumin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Risk of Venous Thromboembolism in Systemic Inflammatory Disorders: a United Kingdom (UK) Matched Cohort Study
Status: COMPLETED
Conditions: Venous Thromboses|Venous Thromboembolism|Deep Vein Thrombosis|Pulmonary Embolism|Rheumatoid Arthritis|Inflammatory Bowel Diseases|Ulcerative Colitis|Crohn Disease|Psoriatic Arthritis
Interventions: OTHER: No intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluate the Efficacy and Safety of KI1106 in Patients Whose TG Level is Not Adequately Controlled With Atorvastatin Calcium Monotherapy While LDL-C is Properly Controlled
Status: COMPLETED
Conditions: Dyslipidemias
Interventions: DRUG: KI1106 4g, QD|DRUG: Atorvastatin Calcium 20mg, QD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Laparoscopically Closing the Hernia Defect in Laparoscopic Ventral Hernia Repair on Postoperative Pain
Status: COMPLETED
Conditions: Ventral Hernias
Interventions: PROCEDURE: The hernia gap is sutured intracorporally
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial to Evaluate the Efficacy and Safety of LANLUMA V to Improve Jawline Contour Deficit
Status: NOT_YET_RECRUITING
Conditions: Jawline Contour Deficit
Interventions: DEVICE: Poly-L-lactin Acid (PLLA) Based Facial Injectable
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Deep Block Versus Moderate Block on the Stress Response After Laparoscopic Gastrectomy
Status: COMPLETED
Conditions: Neuromuscular Blockade
Interventions: DRUG: deep block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: mFOLFOX6 Combined With Dalpiciclib in Patients With Metastatic Colorectal Cancer
Status: RECRUITING
Conditions: Advanced/Metastatic Colorectal Cancer
Interventions: DRUG: Dalpiciclib|DRUG: Oxaliplatin injection|DRUG: Calcium folinate|DRUG: 5-fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Understanding the Impact of Cartridge-Based Electronic Cigarettes and Generated Aerosols on Cardiopulmonary Health
Status: RECRUITING
Conditions: E-Cig Use
Interventions: DRUG: Tobacco flavored liquid type 1|DRUG: Tobacco flavored liquid type 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Research Study to Compare a New Weekly Insulin, Insulin Icodec, and an Available Daily Insulin, Insulin Degludec, Both in Combination With Mealtime Insulin in People With Type 1 Diabetes (ONWARDS 6)
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: DRUG: insulin icodec|DRUG: insulin degludec|DRUG: insulin aspart
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized Clinical Evaluation of the BioFreedom™ Stent
Status: UNKNOWN
Conditions: Stable Angina|Ischemic Heart Disease Silent|ST Elevation (STEMI) and Non-ST Elevation (NSTEMI) Myocardial Infarction|In-stent Coronary Artery Restenosis|Bleeding
Interventions: DEVICE: Biofreedom™ Drug Coated Stent (DCS)|DEVICE: Gazelle™ Bare Metal Coronary Stent (BMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Potential Role of 18F-NaF PET/CT in Diagnosing Cardiac Amyloidosis
Status: UNKNOWN
Conditions: Cardiac Amyloidosis
Interventions: DIAGNOSTIC_TEST: F18-NaF PET/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: 23-valent Polysaccharide Pneumococcal Vaccine in Juvenile Idiopathic Arthritis Patients Under Anti-TNF Therapy
Status: COMPLETED
Conditions: Juvenile Idiopathic Arthritis
Interventions: BIOLOGICAL: anti-TNF
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluate the Effectiveness of Crosslinked HA on the Adhesion Preventing After Trigger Finger Release Surgery
Status: TERMINATED
Conditions: Trigger Finger|Hyaluronic Acid
Interventions: DEVICE: Hyaluronic acid (HA)|DEVICE: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Yohimbine to Enhance Cognitive Behavioral Therapy (CBT) for Social Anxiety
Status: COMPLETED
Conditions: Social Anxiety Disorder
Interventions: BEHAVIORAL: Group Cognitive Behavioral Therapy|DRUG: Yohimbine Hydrochloride|DRUG: Sugar Pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Lenalidomide Combined With G-CHOP in the Treatment of Newly Diagnosed DLBCL With FL
Status: RECRUITING
Conditions: DLBCL - Diffuse Large B Cell Lymphoma|Follicular Lymphoma
Interventions: DRUG: Lenalidomide combined with G-CHOP (LO CHOP)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Proof of Concept Trial of Adjuvant Activity of SWE, a Squalene-based -Oil-in-water Emulsion
Status: WITHDRAWN
Conditions: Influenza
Interventions: BIOLOGICAL: Unadjuvanted seasonal influenza vaccine|BIOLOGICAL: SWE adjuvant mixed with unadjuvanted seasonal influenza vaccine shortly before dosing (SWE + QIV)|BIOLOGICAL: MF59 adjuvanted seasonal influenza vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Plasma Rich in Growth Factors in Post-extraction Sockets
Status: ACTIVE_NOT_RECRUITING
Conditions: Tooth Extraction|Dental Implants
Interventions: DEVICE: PRGF|DEVICE: ABB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SMART Trial for Buprenorphine-Naloxone Medication Assisted Treatment Adherence
Status: ENROLLING_BY_INVITATION
Conditions: Opioid-use Disorder
Interventions: BEHAVIORAL: Contingency Management|BEHAVIORAL: Brief Motivational Interviewing + Substance Free Activities + Mindfulness
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of a Multi-ingredient Night-time Tea on Sleep Quality, Wellbeing and Markers of Immune Function
Status: COMPLETED
Conditions: Mood|Poor Quality Sleep|Good Sleep Habit|Sleep
Interventions: DIETARY_SUPPLEMENT: Night Time Tea|DIETARY_SUPPLEMENT: Control Tea
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Evaluation of a Experimental Denture Adhesive to Prevent Food Ingress
Status: COMPLETED
Conditions: Denture Retention
Interventions: DEVICE: Experimental Denture Adhesive|DEVICE: Reference (Marketed) Denture Adhesive
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Fractional Micro-Needle Radiofrequency and I Botulinum Toxin A for Primary Axillary Hyperhidrosis
Status: COMPLETED
Conditions: Primary Axillary Hyperhidrosis
Interventions: DEVICE: Fractional Micro-Needle Radiofrequency|DRUG: Botulinum toxin type A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of High Caloric Intake at Lunch Against Dinner on Weight Loss
Status: COMPLETED
Conditions: Obesity|Overweight
Interventions: BEHAVIORAL: Lunch as main meal(LM)+ Diet|BEHAVIORAL: Dinner as main meal(DM)+ Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effects of Electroacupuncture With Different Frequencies for Major Depressive Disorder
Status: ACTIVE_NOT_RECRUITING
Conditions: Major Depressive Disorder
Interventions: OTHER: electroacupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dexamethasone Compared to Non-steroidal Anti-inflammatory Drugs in the Treatment of Acute Pericarditis
Status: TERMINATED
Conditions: Pericarditis Acute
Interventions: DRUG: Dexamethasone therapy|DRUG: NSAID therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Refractory Urinary Retention Secondary to Benign Prostatic Hyperplasia (BPH) With Dual Five Alpha Reductase Inhibition Combined With an Alpha Blocker
Status: COMPLETED
Conditions: Urinary Retention|Benign Prostatic Hyperplasia
Interventions: DRUG: Dutasteride
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Totally Implantable Venous Access Devices: Quality of Life and Body Image
Status: COMPLETED
Conditions: Neoplasms Undergoing Chemotherapy
Interventions: BEHAVIORAL: psychological support (interactive/cognitive strategies)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Safety, Tolerance, and Immunogenicity of MAS-1-Adjuvanted Seasonal Inactivated Influenza Vaccine (MER4101)
Status: UNKNOWN
Conditions: Influenza, Human
Interventions: BIOLOGICAL: MER4101|BIOLOGICAL: Inactivated Influenza Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Facilitating Parent Adaptation to Pediatric Transplant: The P-SCIP Trial
Status: COMPLETED
Conditions: Childhood Cancers
Interventions: BEHAVIORAL: Behavioral intervention sessions|OTHER: CD-ROM|OTHER: DVD and pamphlet|OTHER: Respite care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Artemisinin-based Combination Therapy for Treatment of Plasmodium Falciparum Malaria in North Sumatera, Indonesia
Status: COMPLETED
Conditions: Malaria, Falciparum
Interventions: DRUG: Dihydroartemisinin-Piperaquine|DRUG: Artemether-lumefantrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: REVIVE (Response to the Ebola Virus Vaccine)
Status: NOT_YET_RECRUITING
Conditions: Ebola Virus Disease
Interventions: BIOLOGICAL: rVSVDG-ZEBOV-GP Ebola Virus Vaccine (ERVEBO)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Genetics of QT Response to Moxifloxacin
Status: TERMINATED
Conditions: Cardiac Arrhythmias
Interventions: DRUG: Moxifloxacin 400mg once time
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Role of Blood Flow Restriction Therapy in Postop Rehabilitation of Foot and Ankle Injuries
Status: NOT_YET_RECRUITING
Conditions: Fracture of Foot
Interventions: PROCEDURE: BFR+NMES at therapeutic level|PROCEDURE: BFR+NMES at sub therapeutic level
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Differential Effects of Remimazolam and Propofol on Dynamic Cerebral Autoregulation During General Anesthesia
Status: UNKNOWN
Conditions: General Anesthesia|Laparoscopic Cholecystectomy|Remimazolam|Propofol|Dynamic Cerebral Autoregulation
Interventions: DRUG: Remimazolam|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: DKN-01 Inhibition in Advanced Liver Cancer
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: DKN-01 300 mg|DRUG: DKN-01 600 mg|DRUG: Sorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Second-line Treatment With Serplulimab, Lenvatinib, and Paclitaxel in Advanced Gastric Cancer After Prior Immunotherapy
Status: RECRUITING
Conditions: Advanced Gastric or Gastroesophageal Junction Adenocarcinoma
Interventions: DRUG: Serplulimab|DRUG: Lenvatinib|DRUG: Paclitaxel/Paclitaxel-albumin/Paclitaxel liposome
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Phase 2 Study of Atezolizumab and Entinostat in Patients With aTN Breast Cancer With Phase 1b Lead In
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Entinostat|DRUG: Atezolizumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Liposomal Doxorubicin and Etoposide in Treating Patients With Recurrent or Persistent Ovarian, Fallopian Tube, or Peritoneal Cancer
Status: TERMINATED
Conditions: Fallopian Tube Cancer|Ovarian Cancer|Primary Peritoneal Cavity Cancer
Interventions: DRUG: etoposide|DRUG: pegylated liposomal doxorubicin hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Trial of Vitamin D in HIV Progression
Status: COMPLETED
Conditions: HIV Infection
Interventions: DIETARY_SUPPLEMENT: Vitamin D3 (cholecalciferol)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Iadademstat and Gilteritinib in Patients With R/R AML With FMS-like Tyrosine Kinase Mutation (FLT3 Mut+)
Status: RECRUITING
Conditions: Acute Myeloid Leukemia, in Relapse|Acute Myeloid Leukemia Refractory
Interventions: DRUG: Iadademstat|DRUG: Gilteritinib Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SynKIR-110 for Mesothelin Expressing Ovarian Cancer, Cholangiocarcinoma or Mesothelioma
Status: RECRUITING
Conditions: Ovarian Cancer|Cholangiocarcinoma Recurrent|Mesothelioma, Malignant
Interventions: BIOLOGICAL: SynKIR-110, Autologous T cells Transduced with Mesothelin KIR-CAR
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Phase III Trial of Surgery Alone or Surgery Plus Preoperative Gemcitabine-Cisplatin in Clinical Early Stages of Non-small Cell Lung Cancer
Status: SUSPENDED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: RADIATION: Surgery alone or surgery plus preoperative Gemcitabine-Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Decitabine (DAC) Versus Azacitidine (AZA) in Myelodysplastic Syndrome (MDS)
Status: COMPLETED
Conditions: Leukemia
Interventions: DRUG: Azacitidine (AZA) Days 1 - 3|DRUG: Decitabine (DAC)|OTHER: Best Supportive Care (BSC)|DRUG: Azacitidine (AZA) Days 1 - 5
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: VH3739937 Phase 1 Multiple Ascending Dose (MAD) Study in Healthy Volunteers Including Relative Bioavailability (RBA), Optional Food Effect (FE), and Drug-drug Interaction (DDI)
Status: NOT_YET_RECRUITING
Conditions: HIV Infections
Interventions: DRUG: Part A, C and D: VH3739937 500 mg|DRUG: Part A: VH3739937 100 mg|DRUG: Part A and C: Placebo|DRUG: Part B: Treatment A|DRUG: Part B: Treatment B|DRUG: Part B: Treatment C|DRUG: Part B: Treatment D|DRUG: Part B: Treatment E|DRUG: Part D: Probe cocktail
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Population Pharmacokinetics of Teicoplanin, Levofloxacin, Piperacillin/Tazobactam, Meropenem, Vancomycin, Remifentanil, Cefepime, Cefpirome, Sufentanil, Midazolam, Clopidogrel, Ticagrelor, Prasugrel During Veno-arterial Extracorporeal Membrane Oxygenation (VA ECMO)
Status: COMPLETED
Conditions: Cardiac Dysfunction
Interventions: OTHER: Residual blood
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Goal Achievement After Utilizing an Anti-PCSK9 Antibody in Statin Intolerant Subjects-4
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: BIOLOGICAL: Evolocumab|DRUG: Ezetimibe|DRUG: Placebo to Evolocumab|DRUG: Placebo Ezetimibe
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Demonstrate the Bioequivalence of Sitagliptin/Metformin Combination Tablets and Co-administration of Sitagliptin and Metformin as Individual Tablets (0431A-095)
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: sitagliptin phosphate (+) metformin hydrochloride|DRUG: Comparator: metformin 500mg|DRUG: Comparator: sitagliptin|DRUG: Comparator: FMI sitagliptin / metformin 50 mg/500 mg FDC tablet|DRUG: Comparator: FMI sitagliptin/metformin 50 mg/1000 mg FDC tablet|DRUG: Comparator: FMI sitagliptin/metformin 50 mg/850 mg FDC tablet|DRUG: Comparator: metformin 1000 mg|DRUG: Comparator: metformin 850 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Placebo Controlled Comparison of Topical Zirgan Versus Genteal Gel for the Treatment of Adenovirus Conjunctivitis
Status: COMPLETED
Conditions: Keratoconjunctivitis Due to Adenovirus|Viral Shedding
Interventions: DRUG: Zirgan|DRUG: genteal gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Neuromuscular Training and Manual Therapy With Augmented Low-Dye Taping Technique for Correction of Pronated Foot in the Management of Anterior Knee Pain
Status: RECRUITING
Conditions: Anterior Knee Pain Syndrome|Pronated Foot
Interventions: OTHER: Manual Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Open-Label Study to Evaluate the Safety, Tolerability, PK, and Efficacy of INX-315 in Patients With Advanced Cancer
Status: RECRUITING
Conditions: Breast Cancer|Breast Cancer Metastatic|Hormone Receptor Positive Tumor|Human Epidermal Growth Factor 2 Negative Carcinoma of Breast|Ovarian Cancer|CCNE1 Amplification|Solid Tumor|Advanced Cancer|Metastatic Cancer
Interventions: DRUG: INX-315
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial to Evaluate Efficacy, Tolerability, and Pharmacokinetic-Pharmacodynamic Relationship of Fimasartan/Hydrochlorothiazide
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Fimasartan|DRUG: Hydrochlorothiazide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: PTA vs. CB-PTA for Treatment of Femoropopliteal Artery In-Stent Restenosis
Status: COMPLETED
Conditions: Instent Restenosis|Cutting Balloon Angioplasty
Interventions: DEVICE: plain balloon angioplasty|DEVICE: cutting balloon angioplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Efficacy and Safety of Two Methadone Titration Methods for the Treatment of Cancer-related Pain With Inadequate Pain Relief or Intolerable Side Effects When Treated With Level 3 Opioids.
Status: UNKNOWN
Conditions: Pain Related to Cancer
Interventions: DRUG: Methadone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Polio NID and Routine EPI Integration Trial Pakistan
Status: COMPLETED
Conditions: Polio
Interventions: BEHAVIORAL: Vaccine promotion messages|OTHER: Vaccination Verification.|OTHER: Distribution of Plastic Pouches to retain vaccination card
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Closing the Loop in Adults With Type 1 Diabetes Under Free Living Conditions
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: DEVICE: Closed-loop using standard rapid-acting insulin|DEVICE: Closed-loop using faster insulin aspart
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate Safety, Tolerability, and Pharmacokinetics of JNJ-56136379 in Healthy Japanese Adult Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: JNJ-56136379|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Metabolic Differences Between Subtypes of Polycystic Ovary Syndrome
Status: COMPLETED
Conditions: Uric Acid Concentration, Serum, Quantitative Trait Locus 7|Polycystic Ovary Syndrome
Interventions: DIAGNOSTIC_TEST: Serum uric acid level
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Gastrointestinal Biopsychosocial Research Center
Status: COMPLETED
Conditions: Chronic Proctalgia (Also Called Levator Ani Syndrome)
Interventions: BEHAVIORAL: Biofeedback|OTHER: Electrogalvanic stimulation|BEHAVIORAL: Digital massage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Impact of a Prevention Program on Sun Risks in Primary School in Tropical French Region
Status: COMPLETED
Conditions: Melanoma
Interventions: OTHER: MISOLRE prevention program on sun risks|OTHER: "Vivre avec le Soleil" prevention program on sun risks|OTHER: Sun protection equipment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: External Oblique Intercostal Plane Block Versus Thoracic Paravertebral Block for Post Thoracotomy Pain
Status: RECRUITING
Conditions: External Oblique Intercostal Plane Block|Thoracic Paravertebral Block|Post Thoracotomy Pain
Interventions: OTHER: External oblique intercostal plane block|OTHER: Thoracic paravertebral block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Antibody Detection in COVID-19 Cured Patients (SARS-CoV-2-CZ-Immunity)
Status: COMPLETED
Conditions: COVID|SARS-CoV-2
Interventions: DIAGNOSTIC_TEST: Quantitative analysis of anti-SARS-CoV-2-antibodies|DIAGNOSTIC_TEST: SARS-CoV-2 diagnostic rapid test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: An Umbrella Trial Based on Molecular Pathway for Patients With Metastatic TNBC in First-line Treatment (FUTURE-Trop2)
Status: NOT_YET_RECRUITING
Conditions: TNBC - Triple-Negative Breast Cancer
Interventions: DRUG: A1:SG with SHR3680|DRUG: A2:SG|DRUG: B1:SG with SHR1210|DRUG: B2:SG|DRUG: C1:SG with SHR3162|DRUG: C2:SG|DRUG: D1:SG with VEGFRI|DRUG: D2:SG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Discharge Planning for Elderly Patients in the Emergency Department: Use of a Brief Phone Call After Discharge to Improve Medication Utilization and Physician Follow-up
Status: COMPLETED
Conditions: Patient Discharge
Interventions: OTHER: Phone call follow-up|OTHER: Satisfaction survey|OTHER: Control group --- no intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Trial of Two Central Venous Catheter (CVC) Flushing Schemes in Pediatric Hematology and Oncology Patients
Status: TERMINATED
Conditions: Childhood Cancer|Aplastic Anemia|Metabolic Disorders
Interventions: DRUG: Heparin|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Purpose of the Study is to Evaluate the Effect of Ruxolitinib Cream on Itch in Participants With Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: ruxolitinib cream
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Identification of Biomarkers for Patients With Vascular Anomalies
Status: RECRUITING
Conditions: Vascular Anomaly|Generalized Lymphatic Anomaly|Kaposiform Hemangioendothelioma|Kaposiform Lymphangiomatosis|Gorham-Stout Disease|Klippel Trenaunay Syndrome|Congenital Lipomatous Overgrowth, Vascular Malformations, and Epidermal Nevi
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy of a Probiotic Product on Bone Mineral Density (BMD) in Healthy Women in Early Post-menopausal Phase
Status: COMPLETED
Conditions: Osteopenia
Interventions: DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: : Probiotic capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of the Pharmacokinetic and Pharmacodynamic Responses in Healthy and Altered Human Cardiovascular Systems
Status: TERMINATED
Conditions: Drug-Related Side Effects and Adverse Reactions|Cardiovascular System Disease
Interventions: DRUG: Albuterol Sulfate|DRUG: Nicardipine Hydrochloride|DRUG: Dobutamine Hydrochloride|DRUG: Phenylephrine Hydrochloride|DRUG: Verapamil Hydrochloride|DRUG: Phentolamine Mesylate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Impact of Hybrid Closed-loop Insulin Delivery in Type 1 Diabetes on Glycemic Control and PROMs
Status: RECRUITING
Conditions: Diabetes Mellitus, Type 1
Interventions: DEVICE: Medtronic MiniMed 670G|DEVICE: Medtronic MiniMed 780G|DEVICE: Tandem Control-IQ
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Validate Comparability of an Infrared Thermographic Camera Versus Oral, Forehead, and Ear Thermometers When Determining Body Temperature in Adult Participants
Status: COMPLETED
Conditions: Temperature Change, Body
Interventions: DEVICE: Infrared Cameras Inc. (ICI) FMX 400 Infrared (IR) Camera System|DEVICE: Welch Allyn SureTemp Plus 690|DEVICE: Welch Allyn ThermoScan PRO 6000|DEVICE: Infrared Cameras Inc. (ICI) HotSpot Infrared (IR) NonContact Infrared Thermometer
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of Effectiveness of GSK Biologicals' Pneumococcal Conjugate Vaccine 1024850A Against Invasive Disease
Status: COMPLETED
Conditions: Infections, Streptococcal|Streptococcus Pneumoniae
Interventions: BIOLOGICAL: Pneumococcal conjugate vaccine GSK1024850A|BIOLOGICAL: GSK Biologicals' Engerix TM vaccine (Hepatitis B vaccine)|BIOLOGICAL: GSK Biologicals' Havrix TM vaccine (Hepatitis A vaccine)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Dutogliptin in Combination With Filgrastim in Post-Myocardial Infarction
Status: COMPLETED
Conditions: Acute Myocardial Infarction|Acute Myocardial Ischemia|STEMI - ST Elevation Myocardial Infarction
Interventions: DRUG: Dutogliptin Tartrate|DRUG: Filgrastim Injectable Product|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT