pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: The Nonpharmacological Methods in Reducing the Pain Caused by Orogastric Tube Insertion in Preterm Infants
Status: COMPLETED
Conditions: Pain|Preterm|Premature
Interventions: BEHAVIORAL: The swaddling group|BEHAVIORAL: The expressed breast milk group|BEHAVIORAL: The facilitated tucking group|BEHAVIORAL: The swaddling and expressed breast milk group|BEHAVIORAL: The facilitated tucking and expressed breast milk group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Treatment of Predominant Central Sleep Apnoea by Adaptive Servo Ventilation in Patients With Heart Failure
Status: COMPLETED
Conditions: Heart Failure|Sleep Disordered Breathing
Interventions: DEVICE: Europe: AutoSet CS (USA: VPAP Adapt SV)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Timing and Dosage of Acute Intermittent Hypoxia in Persons With SCI
Status: UNKNOWN
Conditions: Spinal Cord Injuries
Interventions: OTHER: Acute Intermittent Hypoxia|OTHER: Sham Acute Intermittent Hypoxia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 1b/2 Safety and Efficacy of APR-246 w/Azacitidine for tx of TP53 Mutant Myeloid Neoplasms
Status: COMPLETED
Conditions: Myelodysplastic Syndrome|Acute Myeloid Leukemia|Myeloproliferative Neoplasm|Chronic Myelomonocytic Leukemia
Interventions: DRUG: APR-246|DRUG: Azacitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Compare I Pilot Study for the Treatment of Subjects With Symptomatic Femoropopliteal Artery Disease
Status: COMPLETED
Conditions: Peripheral Artery Disease
Interventions: DEVICE: Ranger Drug Eluting Balloon|DEVICE: In Pact Drug Eluting Balloon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EndoVascular Treatment With Stent-retriever and/or Thromboaspiration vs. Best Medical Therapy in Acute Ischemic Stroke
Status: COMPLETED
Conditions: Stroke|Ischemic Stroke
Interventions: PROCEDURE: Thrombectomy|DEVICE: Stentriever Solitaire FR® or Penumbra System®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neuromodulation Augmented Cognitive Training to Improve Cognitive Flexibility in Anorexia Nervosa
Status: WITHDRAWN
Conditions: Active tDCS|Sham tDCS
Interventions: DEVICE: Transcranial direct current stimulation|DEVICE: Sham transcranial direct current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Functionality, Cognition And Swallowing Skills In Patients With AcuteSTROKE
Status: COMPLETED
Conditions: Stroke, Acute|Swallowing Disorder|Cognitive Impairment|Stroke|Movement Disorders|Dysphagia
Interventions: DIAGNOSTIC_TEST: Clinician-observed assessment tests
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Monitored Anesthesia Care vs. General Anesthesia for Transcatheter Aortic Valve Replacement
Status: RECRUITING
Conditions: Transcatheter Aortic Valve Replacement
Interventions: PROCEDURE: General Endotracheal Anesthesia|PROCEDURE: Monitored anesthesia care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lavender Aromatherapy on Sleep Quality and Metabolic Parameters of Type 2 Diabetic Patients With Insomnia
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Sleep Disturbance
Interventions: DRUG: Lavender Oil|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ANti-Oxidant in Variant Angina (ANOVA) Trial
Status: UNKNOWN
Conditions: Variant Angina
Interventions: DRUG: Vitamin C and Vitamin E|DRUG: Statin|DRUG: Standard medication for variant angina
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Safety of Combination Therapy of Rosuvastatin and Ezetimibe and Rosuvastatin Monotherapy in Patients With Primary Hypercholesterolemia
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DRUG: Rosuvastatin|DRUG: Ezetimibe
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Predicting the Efficacy and Prognosis of Rectal Cancer Patients Based on ctDNA-MRD Technology
Status: RECRUITING
Conditions: Rectal Adenocarcinoma|Circulating Tumor DNA|Minimal Residual Disease|Neoadjuvant Chemoradiotherapy
Interventions: DIAGNOSTIC_TEST: MRD detection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Treatment of Intracerebral Hemorrhage in Patients on Non-vitamin K Antagonist
Status: COMPLETED
Conditions: Intracerebral Hemorrhage
Interventions: DRUG: Tranexamic acid|DRUG: Saline 0.9%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Extension Family Lifestyle Intervention Project (E-FLIP for Kids)
Status: COMPLETED
Conditions: Obesity
Interventions: BEHAVIORAL: Behavioral Child Tx Contacts|BEHAVIORAL: Behavioral Parent-Tx Contacts|OTHER: Dietary and Physical Activity Information
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fed Study of Benazepril HCl and Hydrochlorothiazide Tablets 20 mg/25 mg to Lotensin HCT® Tablets 20 mg/25 mg
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Benazepril HCl and Hydrochlorothiazide Tablets 20 mg/25 mg|DRUG: Lotensin HCT® Tablets 20 mg/25 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Trial of SHR-4602 Infusion in Patients With SHR-4602 in Subjects With HER2-expressing or HER2-mutated Locally Advanced or Metastatic Solid Tumors
Status: NOT_YET_RECRUITING
Conditions: HER2-expressing or HER2-mutated Locally or Metastatic Solid Tumors
Interventions: DRUG: SHR-4602
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Urelumab (CD137 mAb) With Rituximab for Relapsed, Refractory or High-risk Untreated Chronic Lymphocytic Leukemia (CLL) Patients
Status: WITHDRAWN
Conditions: Leukemia
Interventions: DRUG: Rituximab|DRUG: Urelumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chloroprocaine 3% Gel Eye Drop as Topical Anestheticsin Phacoemulsification.
Status: COMPLETED
Conditions: Cataract
Interventions: DRUG: Chloroprocaine 3%|DRUG: Tetracaine 0.5%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Safety, Tolerability, Pharmacokinetics and Pharmacodynamic Activity of Very Low Dose-Glucagon in Subjects With Type 1 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: DRUG: very low dose (VLD) glucagon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Functional Lesion Assessment of Intermediate Stenosis to Guide Revascularisation
Status: UNKNOWN
Conditions: Coronary Artery Disease
Interventions: DEVICE: iFR|DEVICE: FFR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of Darbepoetin Alfa for the Treatment of Anemia in Subjects With Non-Myeloid Malignancy Receiving Multicycle Chemotherapy
Status: COMPLETED
Conditions: Anemia|Non-Myeloid Malignancies
Interventions: DRUG: Darbepoetin alfa - 2.25 mcg/kg|DRUG: Darbepoetin alfa - 500mcg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment for Tachyphylaxis to Topical Corticosteroids in the Treatment of Psoriasis
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: Halobetasol 0.05% ointment|DRUG: Placebo Ointment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: BASIC_SCIENCE
Clinical trial: To Examine the Lung When People With Diabetes Take an Inhaled Form of Insulin, Compared to Subcutaneous Insulin.
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Inhaled insulin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect on Obsessive-Compulsive Beliefs and Symptoms of MCT-OCD
Status: NOT_YET_RECRUITING
Conditions: Obsessive-Compulsive Disorder
Interventions: BEHAVIORAL: Metacognitive Training for Obsessive-Compulsive Disorder (MCT-OCD)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Improving Learning-based Treatment of Cocaine Dependence With Medication
Status: COMPLETED
Conditions: COCAINE-RELATED DISORDERS
Interventions: DRUG: d-cycloserine|DRUG: sugar pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MK-7625A Versus Meropenem in Pediatric Participants With Complicated Urinary Tract Infection (cUTI) (MK-7625A-034)
Status: COMPLETED
Conditions: Complicated Urinary Tract Infection|Pyelonephritis
Interventions: DRUG: Ceftolozane/Tazobactam|DRUG: Meropenem
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Diagnosis of Pancreatic Cysts: Endoscopic Ultrasound With Fine Needle Aspiration (EUS/FNA), Direct Visualization, and Confocal Laser-induced Endomicroscopy-A Pilot Study
Status: COMPLETED
Conditions: Pancreatic Cysts
Interventions: DEVICE: Direct visualization and needle based confocal laser-induced endomicroscopy miniprobe
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety of Acyclovir-penciclovir Cream Versus an Abreva in the Suppression of Herpes Simplex Virus Eruptions
Status: NOT_YET_RECRUITING
Conditions: Herpes Simplex Oral
Interventions: DRUG: acyclovir-penciclovir cream|DRUG: Abreva
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of TMC435 in Participants With Genotype 1 Hepatitis C Virus (HCV) Infection
Status: COMPLETED
Conditions: Hepatitis C, Chronic
Interventions: DRUG: TMC435|DRUG: Peginterferon alfa-2b (pegIFN alfa-2b)|DRUG: Ribavirin (RBV)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multidimensional Prehabilitation in Pancreatic Surgery for Pancreatic and Periampullary Neoplasms
Status: ENROLLING_BY_INVITATION
Conditions: Pancreatic Neoplasms|Periampullary Carcinoma
Interventions: OTHER: Exercise|DIETARY_SUPPLEMENT: Nutritional|BEHAVIORAL: Behavioral Medicine|BEHAVIORAL: Smoking Cessation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Eptinezumab as an Adjunct to Standard of Care for Migraine in an Acute Emergency Context
Status: NOT_YET_RECRUITING
Conditions: Migraine|Chronic Migraine
Interventions: BIOLOGICAL: Eptinezumab|OTHER: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Oral Administration of Actitan-F in Paediatric Diarrhoea
Status: RECRUITING
Conditions: Chronic Diarrhoea of Infants and/or Young Children
Interventions: DEVICE: Lenodiar Pediatric|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Effectiveness of Different Drugs Used to tr€at Patients in Rheumatoid Arthritis Saudi Database (RASD)"
Status: RECRUITING
Conditions: Rheumatoid Arthritis RA
Interventions: OTHER: biological and targeted synthetic disease modifying anti rheumatic drugs (bDMARDs) and (tsDMARDs)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Trial of Safety and Efficacy of Rasagiline in Patients With Amyotrophic Lateral Sclerosis (ALS)
Status: COMPLETED
Conditions: Amyotrophic Lateral Sclerosis (ALS)
Interventions: DRUG: rasagiline
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pediatric FEcal Microbiota Transplant for Ulcerative Colitis
Status: COMPLETED
Conditions: Inflammatory Bowel Disease|Ulcerative Colitis
Interventions: BIOLOGICAL: Fecal Microbiota Enema|BIOLOGICAL: Normal Saline Enema
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Gentian Violet Vs. Nystatin Oral Suspension for Treatment of Oropharyngeal Candidiasis
Status: COMPLETED
Conditions: HIV-1 Infection
Interventions: DRUG: Gentian Violet|DRUG: Nystatin oral suspension
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Tucatinib Plus Trastuzumab Deruxtecan in HER2+ Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: HER2 Positive Breast Cancer
Interventions: DRUG: tucatinib|DRUG: trastuzumab deruxtecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Impact of Age on Botulinum Toxin Potency in Facial Rhytides Treatment
Status: UNKNOWN
Conditions: Aging|Botulinum Toxin|Facial Wrinkles
Interventions: DRUG: 30 Units of botulinum toxin|DRUG: 50 Units of botulinum toxin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: "Extended" (Alternate Day) Antipsychotic Dosing
Status: RECRUITING
Conditions: Schizophrenia and Related Disorders|Drug Administration Schedule|Drug Therapy|Antipsychotic Agents
Interventions: DRUG: Risperidone|DRUG: Olanzapine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Mobilization on Gastric Emptying Time
Status: COMPLETED
Conditions: Anesthesia|Fasting
Interventions: OTHER: group WM|OTHER: group WR|OTHER: Group AR|OTHER: Group AM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Comparison of 2 Days Versus 5 Days of Octreotide After Endoscopic Therapy in Preventing Early Esophageal Varices Rebleed : A Randomized Controlled Study
Status: UNKNOWN
Conditions: Esophageal Varices
Interventions: DRUG: Octreotide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Center for Research and Education on Aging and Technology Enhancement - CREATE V
Status: NOT_YET_RECRUITING
Conditions: Mild Cognitive Impairment
Interventions: BEHAVIORAL: Project 1, Phase 2: VR Program for Social, Activity, and Cognitive Engagement|BEHAVIORAL: Project 2, Phase 2: Intelligent Adaptive System|BEHAVIORAL: Project 3, Phase 3: Intelligent Decision Support Tool
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Single Dose Study to Evaluate the PK-PD Response and Safety of PHA-794428 in Children With Growth Hormone Deficiency
Status: TERMINATED
Conditions: Growth Hormone Deficiency
Interventions: DRUG: PHA-794428
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Bundling Gentle Body Massage Along With Regular Position Change Under Phototherapy
Status: COMPLETED
Conditions: Hyperbilirubinemia, Neonatal
Interventions: OTHER: Gentle Body message|OTHER: Routine NICU Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Stem Cells Therapy in Degenerative Diseases of the Retina
Status: UNKNOWN
Conditions: Retinal Degeneration|Retinitis Pigmentosa|Age Related Macular Degeneration|Stargardt Disease 1
Interventions: BIOLOGICAL: Stem/progenitor cells transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effect of Steroids on Cerebral Inflammation and Neuronal Damage After Surgical Aortic Valve Replacement
Status: COMPLETED
Conditions: Aortic Stenosis
Interventions: DRUG: Methylprednisolone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: STRIDE: Stress Reduction in Dementia Caregivers
Status: ACTIVE_NOT_RECRUITING
Conditions: Caregiver Stress
Interventions: BEHAVIORAL: Healthy Minds Program (HMP)|BEHAVIORAL: Wellness App (WA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Side Effects Involving the Heart in Women With Breast Cancer Receiving Doxorubicin and Trastuzumab
Status: COMPLETED
Conditions: Breast Cancer|Cardiac Toxicity|Cardiovascular Complications
Interventions: BIOLOGICAL: trastuzumab|DRUG: doxorubicin hydrochloride|GENETIC: polymorphism analysis|OTHER: laboratory biomarker analysis|OTHER: questionnaire administration|PROCEDURE: assessment of therapy complications|PROCEDURE: magnetic resonance imaging
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Tele-rehabilitation Using tDCS Combined With Exercise in People With Spinal Cord Injury
Status: ACTIVE_NOT_RECRUITING
Conditions: Spinal Cord Injury|Incomplete Spinal Cord Injury
Interventions: DEVICE: Transcranial direct current stimulation (Active)|DEVICE: Transcranial direct current stimulation (Sham)|OTHER: Telerehabilitation exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acceptability and Feasibility of Work-Oriented Social-Cognitive Skills Training for Veterans With Serious Mental Illness
Status: RECRUITING
Conditions: Schizophrenia|Bipolar Disorder|Depressive Disorder, Major|Stress Disorder, Post-Traumatic
Interventions: BEHAVIORAL: Social Cognition and Interaction Training-Work Edition (SCIT-WE)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of 3M™ ESPE™ Adper™ Scotchbond™ SE Self-Etch Adhesive in Class I and Class II Restorations in Adults
Status: COMPLETED
Conditions: Dental Caries
Interventions: DEVICE: 3M ESPE Adper Scotchbond SE|DEVICE: 3M ESPE Adper Scotchbond 1XT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Molecular Imaging of Gastrin Releasing Peptide Receptors Using Labeled Technetium-99m RM26
Status: COMPLETED
Conditions: Prostate Cancer|Breast Cancer Female
Interventions: DIAGNOSTIC_TEST: whole body study and SPECT with 99mTc-RM26
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety and Efficacy of the Novel Selective Nicotinic Receptor Partial Agonist, CHANTIX (Varenicline) in Patients With Acute Coronary Syndrome
Status: UNKNOWN
Conditions: Smoking|Acute Coronary Syndrome
Interventions: DRUG: Varenicline 100 mg by mouth twice daily|DRUG: control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pregnancy/Implantation Rates Using a Day 3 Score Versus Graduated Embryo Score Plus a Biochemical Marker (sHLA-G)
Status: COMPLETED
Conditions: Infertility
Interventions: DRUG: Human derived FSH
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: Inhalation Low Dose Radionuclide Therapy in Treatment COVID-19
Status: COMPLETED
Conditions: Covid19|Pneumonia, Viral
Interventions: RADIATION: 99mTc-pertechnetate aerosol|DRUG: 99mTc-pertechnetate aerosol
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing the Efficacy of Accelerated vs. Standard fMRI-guided iTBS in Treating Adolescents Depression
Status: NOT_YET_RECRUITING
Conditions: Depression|Depressive Disorder, Major
Interventions: DEVICE: Theta Burst Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Tolerance of Peg-interferon Alpha 2a Added to Tenofovir and Emtricitabine in AgHBe Positive HBV-HIV Co-infected Patients
Status: COMPLETED
Conditions: Hepatitis B|HIV Infections
Interventions: DRUG: TRUVADA (EMTRICITABINE + TENOFOVIR DF)|BIOLOGICAL: PEGASYS 180μg (Interféron pégylé alpha -2a)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Procalcitonin as a Marker of Antibiotic Therapy in Patients With Lower Respiratory Tract Infections
Status: UNKNOWN
Conditions: Pneumonia|Acute Exacerbation of Chronic Obstructive Airways Disease
Interventions: OTHER: PCT-level|BEHAVIORAL: Antibiotic treatment based on PCT-level
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Impact of Microbe Literacy Initiative on Improved Vaccine Uptake in Peri-urban Slum Areas in Kathmandu, Nepal
Status: UNKNOWN
Conditions: Vaccine Acceptance
Interventions: OTHER: Microbe literacy Program in the form of workshop
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Administration of Oral Contraceptives at Different Times of the Follicular Phase of the Menstrual Cycle
Status: COMPLETED
Conditions: Contraception
Interventions: DRUG: 0.15mg desogestrel /0.03mg ethinyl estradiol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose-Ranging Study for Miconazole Oil for Treatment of Otomycosis
Status: COMPLETED
Conditions: Otomycosis
Interventions: DRUG: 7-Day Miconazole Oil (Miconazole 2%)|DRUG: 14-Day Miconazole Oil (Miconazole 2%)|DRUG: 14-Day Placebo - Oil Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: EPOCH-R Chemotherapy Plus Bortezomib to Treat Mantle Cell Lymphoma
Status: COMPLETED
Conditions: Lymphoma, Mantle Cell|Mantle Cell Lymphoma
Interventions: DRUG: Rituximab (R)|BIOLOGICAL: EPOCH|DRUG: Bortezomib (B)|DRUG: Bortezomib|DRUG: Bortezomib or observation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Effect of Ofatumumab in Treatment Naïve, Very Early RRMS Patients Benchmarked Against Healthy Controls.
Status: ACTIVE_NOT_RECRUITING
Conditions: Relapse Remitting Multiple Sclerosis
Interventions: DRUG: Ofatumumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Web Based Education Based on Self-Care Deficiency Theory on Self-Care Power and Self-Efficacy and Perceived Social Support in Patients Receiving Peritoneal Dialysis
Status: UNKNOWN
Conditions: Self-Care|Self Efficacy|Perceived Social Support|Peritoneal Dialysis
Interventions: OTHER: The Effect of Web Based Education Based on Self-Care Deficiency Theory on Self-Care Power and Self-Efficacy and Perceived Social Support in Patients Receiving Peritoneal Dialysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Laparoscopic Hysterectomy Via a Single Port, Peri-umbilical Technique Versus a Conventional Laparoscopic Technique
Status: TERMINATED
Conditions: Hysterectomy
Interventions: PROCEDURE: Single-port, peri-umbilical hysterectomy|PROCEDURE: Multi-port hysterectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Tetravalent Dengue Virus Purified Inactivated Vaccine and Tetravalent Dengue Virus Live Attenuated Vaccine
Status: UNKNOWN
Conditions: Dengue Virus
Interventions: BIOLOGICAL: TDENV-PIV|BIOLOGICAL: TDENV-LAV F17
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effectiveness of Osteopathic Manipulative Medicine in the Management of Headaches Associated With Post Concussion Syndrome
Status: COMPLETED
Conditions: Headache|Post-Concussion Syndrome
Interventions: OTHER: Osteopathic Manipulative Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: INTERVAL: Ipilimumab and Nivolumab Combination Therapy: A Study of a Supervised or Semi-Supervised Exercise InteRVention or Usual Care With Functional Capacity and Quality of Life Evaluations in Subjects With Advanced or Metastatic RenAL Cell Carcinoma
Status: TERMINATED
Conditions: Metastatic Renal Cell Carcinoma
Interventions: BEHAVIORAL: Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Piezocision-assisted Orthodontic Treatment Combined With Alveolar Bone Regeneration
Status: COMPLETED
Conditions: Patients Requiring Mandible Orthodontic Treatment
Interventions: PROCEDURE: Piezocision combined minimally invasive alveolar bone regeneration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effects of Intragastric Administration of Nutrients on Executive Control in Healthy Subjects.
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DIETARY_SUPPLEMENT: intragastric infusion of nutrient
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Duration of the Suppressive Effects of Desloratadine on Allergen Prick Tests After Discontinuation (P04441)
Status: COMPLETED
Conditions: Hypersensitivity
Interventions: DRUG: desloratadine|DRUG: levocetirizine|DRUG: Desloratadine placebo tablet|DRUG: Levocetirizine placebo capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Iliopsoas Plane Block After Total Hip Arthroplasty
Status: COMPLETED
Conditions: Total Hip Arthroplasty
Interventions: PROCEDURE: iliopsoas plane block group|PROCEDURE: sham block group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Nebivolol Versus Metoprolol Succinate on Endothelial Function
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: metoprolol succinate|DRUG: Nebivolol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Skeletally Anchored Maxillary Expander Via Two Approaches of Microosteoperforations
Status: ACTIVE_NOT_RECRUITING
Conditions: Posterior Crossbite
Interventions: DEVICE: skeletally anchored maxillary expander
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: To Demonstrate the Relative Bioavailability of Clarithromycin 250 mg Tablets Under Fasting Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Clarithromycin 250 mg Tablets (Geneva, USA)|DRUG: Biaxin 250 mg Tablets (Abbott Laboratories, Inc, USA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose Finding Study of MCI-186 in Acute Ischemic Stroke
Status: TERMINATED
Conditions: Acute Ischemic Stroke
Interventions: DRUG: Continuous infusion high-dose MCI-186|DRUG: Continuous infusion low-dose MCI-186|DRUG: Continuous infusion placebo|DRUG: Approved dosing regimen MCI-186|DRUG: Approved dosing regimen placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Meloxicam vs. Naproxen Sodium in Patients With Acute Non Bacterial Pharyngitis or Pharyngo-tonsillitis
Status: COMPLETED
Conditions: Pharyngitis
Interventions: DRUG: Meloxicam low|DRUG: Meloxicam high|DRUG: Naproxen sodium|DRUG: Meloxicam placebo low|DRUG: Meloxicam placebo high|DRUG: Naproxen sodium placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Aphtous Ulcers With Photodynamic Therapy
Status: COMPLETED
Conditions: Oral Ulcer|Aphthous Recurrent Ulcers
Interventions: COMBINATION_PRODUCT: Photodynamic therapy (indocyanine green+laser)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Early Intensive Antihypertensive Treatment in High-Risk Population of intraCerebral Hemorrhage ExpanSion Predicted by Artificial Intelligence
Status: NOT_YET_RECRUITING
Conditions: Cerebral Hemorrhage
Interventions: PROCEDURE: Early intensive antihypertensive treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Combined Neurofeedback-TMS Intervention for Alcohol Use Disorder
Status: NOT_YET_RECRUITING
Conditions: Alcohol Use Disorder
Interventions: BEHAVIORAL: Realtime fMRI Neurofeedback - Active|DEVICE: TMS - Active|BEHAVIORAL: Realtime fMRI Neurofeedback - Yoked Sham|DEVICE: TMS - Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Catheter Cryoablation Versus Antiarrhythmic Drug as First-Line Therapy of Paroxysmal Atrial Fibrillation
Status: COMPLETED
Conditions: Symptomatic Paroxysmal Atrial Fibrillation Without Clinically Significant Heart Diseases
Interventions: DEVICE: cryoballoon ablation system|DRUG: Antiarrhythmic Drugs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open-Label Extension Trial to Characterize the Long-term Safety and Tolerability of Elamipretide in Subjects With Genetically Confirmed Primary Mitochondrial Myopathy (PMM)
Status: TERMINATED
Conditions: Primary Mitochondrial Disease
Interventions: DRUG: elamipretide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effect of Triamcinolone at Different Doses on LIA During TKA
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: DRUG: without triamcinolone|DRUG: 20mg triamcinolone|DRUG: 40mg triamcinolone|DRUG: 80mg triamcinolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: HoLEP vs. Greenlight 532nm-laser PVEP vs. Bipolar TURP in Management of Moderate/ Large BPH
Status: COMPLETED
Conditions: Benign Prostate Hyperplasia|Lower Urinary Tract Symptoms
Interventions: PROCEDURE: 532nm-laser photoselective vapo-enucleation of the prostate)|PROCEDURE: Holmium laser enucleation of prostate|PROCEDURE: Bipolar TURP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Intratumoral REOLYSIN® in Combination With Gemcitabine and Cisplatin as Neoadjuvant Therapy in Muscle-invasive Transitional Cell Carcinoma of the Bladder
Status: WITHDRAWN
Conditions: Muscle-invasive Transitional Cell Carcinoma of the Bladder
Interventions: BIOLOGICAL: REOLYSIN®|DRUG: Gemcitabine|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of LNS and MNP Supplements to Prevent Malnutrition in Women and Their Children in Bangladesh
Status: COMPLETED
Conditions: Malnutrition
Interventions: DIETARY_SUPPLEMENT: LNS-PLW|DIETARY_SUPPLEMENT: LNS-Child|DIETARY_SUPPLEMENT: MNP|DIETARY_SUPPLEMENT: IFA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: IACS-010759 in Advanced Cancers
Status: COMPLETED
Conditions: Advanced Malignant Solid Neoplasm|Anatomic Stage III Breast Cancer AJCC v8|Anatomic Stage IIIA Breast Cancer AJCC v8|Anatomic Stage IIIB Breast Cancer AJCC v8|Anatomic Stage IIIC Breast Cancer AJCC v8|Anatomic Stage IV Breast Cancer AJCC v8|Estrogen Receptor Negative|HER2/Neu Negative|Metastatic Malignant Solid Neoplasm|Pancreatic Ductal Adenocarcinoma|Progesterone Receptor Negative|Prognostic Stage III Breast Cancer AJCC v8|Prognostic Stage IIIA Breast Cancer AJCC v8|Prognostic Stage IIIB Breast Cancer AJCC v8|Prognostic Stage IIIC Breast Cancer AJCC v8|Prognostic Stage IV Breast Cancer AJCC v8|Recurrent Lymphoma|Refractory Lymphoma|Stage II Pancreatic Cancer AJCC v8|Stage IIA Pancreatic Cancer AJCC v8|Stage IIB Pancreatic Cancer AJCC v8|Stage III Pancreatic Cancer AJCC v8|Stage IV Pancreatic Cancer AJCC v8|Triple-Negative Breast Carcinoma|Unresectable Solid Neoplasm
Interventions: DRUG: Oxidative Phosphorylation Inhibitor IACS-010759|OTHER: Pharmacodynamic Study|OTHER: Pharmacokinetic Study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dentures Biofilm and Artificial Biofilm Substitute
Status: COMPLETED
Conditions: Biofilm
Interventions: OTHER: 12h and 36h Biofilm formation on PMMA (Palapress®) dentures and samples worn by participants and brushing cycles needed to remove it.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Efficacy And Safety Of Lacidipine And Amlodipine Once-Daily Treatment In Hypertensive Adult Patients
Status: COMPLETED
Conditions: Uncomplicated Hypertension|Hypertension|Essential
Interventions: DRUG: Lacidipine 4 or 6 mg (oral)|DRUG: Amlodipine 5 or 10 mg(oral)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Stromal Vascular Fraction Cell Therapy to Improve the Repair of Rotator Cuff Tears
Status: ACTIVE_NOT_RECRUITING
Conditions: Rotator Cuff Tear|Muscle Atrophy|Tendon Tear
Interventions: DEVICE: Autologous Stomal Vascular Fraction Material|DEVICE: Ringer's solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Cybis™ 10:25 THC:CBD Oil in Adults With Chronic Back/Neck Pain
Status: COMPLETED
Conditions: Chronic Pain|Neck Pain|Back Pain|Pain|Pain, Chronic|Pain, Back|Pain, Neck|CBD|THC
Interventions: DRUG: Cybis™ 10:25 THC:CBD oil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility Study of the Medication Review With Follow up Service for Patients With Polypharmacy in Swiss Community Pharmacies
Status: RECRUITING
Conditions: Chronic Disease
Interventions: OTHER: Medication review with follow up or MaJ? for the acronym in french
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Intradialytic Progressive Resistance Training for Maintenance Haemodialysis Patients
Status: COMPLETED
Conditions: Chronic Kidney Disease
Interventions: OTHER: Progressive resistance training programme|OTHER: Sham exercise|OTHER: Progressive resistance training|OTHER: Sham exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Reverse T-stenting and Minimal Protrusion With External Minicrush for Treatment of Complex Coronary Bifurcation
Status: NOT_YET_RECRUITING
Conditions: Coronary Artery Disease|Coronary Stenosis|Coronary Disease
Interventions: PROCEDURE: Percutaneous Coronary Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Sodium Selenite as a Cytotoxic Agent in Advanced Carcinoma
Status: UNKNOWN
Conditions: Malignant Tumor|Treatment Resistant Disorders|Tumor Progression
Interventions: DRUG: Sodium selenite (Introselen)|DRUG: Sodium selenite
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Positron Emission Tomograph(PET) Imaging Explores the Role of SF-DEVD-2 in Monitoring Tumor Efficacy
Status: RECRUITING
Conditions: Breast Cancer Stage II|Breast Cancer Stage III|Solid Tumor
Interventions: DRUG: [18F]SF-DEVD-2|DRUG: [18F]-FDG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation of the Precision of the Microperimetry Function of the Spectral OCT/SLO
Status: COMPLETED
Conditions: Age-Related Macular Degeneration|Geographic Atrophy|Diabetic Retinopathy|Macular Edema|Retinal Vein Occlusion|Central Serous Retinopathy|Pattern Dystrophy of Macula|Epiretinal Membrane|Macular Hole
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical Trial to Evaluate the Efficacy and Safety of CKD-390 Tablet
Status: UNKNOWN
Conditions: Chronic Hepatitis B
Interventions: DRUG: CKD-390|DRUG: viread
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Role Of Physical Therapy In Relieving Constipation In Children With Spastic Cerebral Palsy
Status: COMPLETED
Conditions: Cerebral Palsy, Spastic
Interventions: OTHER: Progressive Physical Therapy|OTHER: Maintenance Physical Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: First in Humans to Evaluate Collagen Patches With Stem Cells in Patients With Ischemic Left Ventricular Dysfunction
Status: UNKNOWN
Conditions: Heart Failure With Reduced Ejection Fraction
Interventions: DEVICE: VB-C01
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bevacizumab/Doxorubicin/Radiation for Sarcoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Sarcoma
Interventions: DRUG: Bevacizumab|DRUG: Doxorubicin|RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of BNP105 in the Treatment of Recurrent Aphthous Stomatitis
Status: RECRUITING
Conditions: Aphthous Stomatitis
Interventions: DRUG: BNP105 (25 + 25 + 15)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Web-based Interventions on Nonalcoholic Fatty Liver Disease (NAFLD) in Obese Children
Status: COMPLETED
Conditions: NAFLD|Web|Childhood Obesity
Interventions: OTHER: web-based intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Subcutaneously Infiltrated Nicardipine on the Success Rate of Radial Artety Cannulation
Status: ENROLLING_BY_INVITATION
Conditions: Radial Artery Cannulation
Interventions: DRUG: Nicardipine|OTHER: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Ascorbic Acid and Chemotherapy for the Treatment of Relapsed or Refractory Lymphoma, CCUS, and Chronic Myelomonocytic Leukemia
Status: RECRUITING
Conditions: Clonal Cytopenia of Undetermined Significance|High Grade B-Cell Lymphoma With MYC and BCL2 or BCL6 Rearrangements|Recurrent Diffuse Large B-Cell Lymphoma|Recurrent Hodgkin Lymphoma|Recurrent Lymphoma|Refractory Diffuse Large B-Cell Lymphoma|Refractory Lymphoma|Chronic Myelomonocytic Leukemia
Interventions: DIETARY_SUPPLEMENT: Ascorbic Acid|DRUG: Carboplatin|DRUG: Cisplatin|DRUG: Cytarabine|DRUG: Dexamethasone|DRUG: Etoposide|DRUG: Gemcitabine Hydrochloride|DRUG: Ifosfamide|OTHER: Laboratory Biomarker Analysis|DRUG: Oxaliplatin|OTHER: Placebo Administration|OTHER: Questionnaire Administration|BIOLOGICAL: Rituximab|DRUG: Decitabine|PROCEDURE: Biospecimen Collection|PROCEDURE: Core Biopsy|PROCEDURE: Bone Marrow Aspiration|PROCEDURE: Bone Marrow Biopsy|PROCEDURE: Echocardiography|PROCEDURE: Positron Emission Tomography|PROCEDURE: Magnetic Resonance Imaging|PROCEDURE: Central Venous Cannula Insertion|PROCEDURE: Portacath Placement|PROCEDURE: Computed Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Equivalence of Estradiol Vaginal Cream 0.01% to Estrace® Cream 0.01% in Atrophic Vaginitis
Status: COMPLETED
Conditions: Atrophic Vaginitis
Interventions: DRUG: Generic Estradiol Vaginal Cream USP, 0.01%|DRUG: Estrace® Vaginal Cream USP, 0.01%|DRUG: Vehicle Vaginal Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: EEG Monitoring Under Anaesthesia in Children: Towards Personalized Anaesthesia Care
Status: COMPLETED
Conditions: Depth of Anaesthesia|EEG|Anesthesia Emergence Delirium
Interventions: DEVICE: Sedline EEG sensor placement|DEVICE: Sedline EEG monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Predictive Model of Recovery in Patients With Chronic Nonspecific Neck Pain Undergoing Manual Therapy and Exercise
Status: UNKNOWN
Conditions: Chronic Nonspecific Neck Pain
Interventions: OTHER: Manual Therapy and Exercise (Physiotherapy Intervention)|OTHER: Usual Care (Physiotherapy Intervention)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Neostigmine Versus Sugammadex on Renal Functions
Status: ACTIVE_NOT_RECRUITING
Conditions: Sugammadex|Neostigmine
Interventions: DRUG: Neostigmine|DRUG: Sugammadex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Imatinib and Toripalimab in Patients With Locally Advanced/Metastatic Melanoma Harbored With CKIT Mut
Status: UNKNOWN
Conditions: Advanced Melanoma
Interventions: DRUG: JS001+Imatinib mesylate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Two Arm Trial of Axitinib and Carboplatin/Paclitaxel in Melanoma
Status: COMPLETED
Conditions: Melanoma
Interventions: DRUG: Axitinib|DRUG: Carboplatin|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Randomized Evaluation of a Two and Three Piece Total Ankle Replacement
Status: COMPLETED
Conditions: Ankle Osteoarthritis
Interventions: DEVICE: Salto-Talaris Total Ankle Replacement|DEVICE: STAR Total Ankle Replacement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT