pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Efficacy and Safety of 300 IR Sublingual Immunotherapy (SLIT) Tablets in Children Suffering From Grass Pollen Rhinoconjunctivitis
Status: COMPLETED
Conditions: Allergy
Interventions: DRUG: 300 IR grass pollen allergen extract tablet|DRUG: Placebo tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: EXecutive Registry: Evaluating XIENCE V® in a Multi Vessel Disease
Status: COMPLETED
Conditions: Coronary Disease|Coronary Artery Disease|Coronary Artery Stenosis|Coronary Artery Restenosis
Interventions: DEVICE: Coronary artery placement of a drug-eluting stent
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of ImmunoPet Imaging Using 89Zr-DFO-REGN5054 in Adult Participants With Solid Cancers Treated With Cemiplimab
Status: RECRUITING
Conditions: Advanced Solid Tumor|Metastatic Solid Tumor
Interventions: DRUG: 89Zr˗DFO˗REGN5054|DRUG: cemiplimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hip Viscosupplementation: What is the Best Dosage?
Status: UNKNOWN
Conditions: Osteoarthritis
Interventions: PROCEDURE: articular lavage with saline injection|DRUG: 1 ampoule of Hylan GF-20|DRUG: 2 ampoules of Hylan GF-20|DRUG: 3 ampoules of Hylan GF-20
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Experimental Mouthwashes
Status: COMPLETED
Conditions: Gingivitis|Plaque
Interventions: OTHER: Colgate (R) Cavity Protection Toothpaste|DEVICE: Colgate (R) Cello Toothbrush|OTHER: Prototype 1 Mouthwash|OTHER: Prototype 2 Mouthwash|OTHER: Prototype 3 Mouthwash|OTHER: Listerine (R) Cool Mint (R) Antiseptic Mouthwash|OTHER: 5% Hydroalcohol Mouthwash
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: OTHER
Clinical trial: Clinical Study of the Efficacy and Safety of SHR-1819 Injection in Adult Patients With Prurigo Nodularis
Status: NOT_YET_RECRUITING
Conditions: Prurigo Nodularis
Interventions: DRUG: SHR-1819 injection|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Does the Timing of When High Intensity Intermittent Exercise is Undertaken Matter?
Status: UNKNOWN
Conditions: Weight Loss|Weight Change, Body|Nutritional and Metabolic Disease
Interventions: OTHER: HIIE-First|OTHER: Continuous-First
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Resting-State Functional MRI in Glioma Patients Before and After Surgery
Status: RECRUITING
Conditions: Brain Mass|Glioma
Interventions: PROCEDURE: Functional Magnetic Resonance Imaging|PROCEDURE: Magnetic Resonance Imaging|PROCEDURE: Resting State Functional Connectivity Magnetic Resonance Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of Siremadlin in Combination With Venetoclax Plus Azacitidine in Adult Participants With Acute Myeloid Leukemia (AML) Who Are Ineligible for Chemotherapy.
Status: COMPLETED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: siremadlin|DRUG: venetoclax|DRUG: azacitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Trial of Rectal Indomethacin and Papillary Spray of Epinephrine Versus Rectal Indomethacin to Prevent Post-ERCP Pancreatitis
Status: COMPLETED
Conditions: Post-ERCP Acute Pancreatitis
Interventions: DRUG: Rectal Indomethacin|DRUG: Epinephrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Cranberry for the Prevention of Urinary Tract Infections
Status: UNKNOWN
Conditions: Urinary Tract Infection
Interventions: DIETARY_SUPPLEMENT: Cranberry concentrate|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study in Men With Overweight to Test How Well Different Doses of BI 1820237 Are Tolerated When Given as an Injection Alone or in Combination With Liraglutide
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BI 1820237|DRUG: Placebo|DRUG: Saxenda®|DRUG: Paracetamol-ratiopharm®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Remifentanil for Mechanically Ventilated Patients in Intensive Care Unit
Status: RECRUITING
Conditions: Analgesia
Interventions: DRUG: Remifentanil|DRUG: Fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Virtual Reality Glasses and Stress Ball Application on Pain, Anxiety and Patient Satisfaction in Intramuscular Injection Application
Status: NOT_YET_RECRUITING
Conditions: Pain and Anxiety During Intramuscular Injection
Interventions: OTHER: Virtual Reality Glasses Application|OTHER: Stress Ball Application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of the Safety and Pharmacokinetics of Oleander 4X in Healthy Volunteers
Status: UNKNOWN
Conditions: Flu-like Symptoms
Interventions: DRUG: Oleander 4X - single|DRUG: Oleander 4X - double|DRUG: Oleander 4X - quadruple|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Efficacy and Safety of AXS-05 in Subjects With Alzheimer's Disease Agitation
Status: RECRUITING
Conditions: Agitation in Patients With Dementia of the Alzheimer's Type|Alzheimer Disease|Agitation
Interventions: DRUG: AXS-05|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Counseling to Optimize Adherence in Expectant Mothers With Inflammatory Bowel Disease
Status: UNKNOWN
Conditions: Inflammatory Bowel Diseases|Medication Adherence|Crohn Disease|Ulcerative Colitis
Interventions: OTHER: Interactive educational video|BEHAVIORAL: Initial in-person counseling with an IBD nurse|BEHAVIORAL: Motivational interviewing|BEHAVIORAL: Telemedicine-based follow-up|OTHER: Monthly follow-up questionnaires|OTHER: Comprehensive questionnaires
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: DISKUS vs. ELLIPTA Device Preference Study in Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DEVICE: ELLIPTA|DEVICE: DISKUS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of Ocriplasmin in Inducing Total PVD in Subjects With NPDR
Status: TERMINATED
Conditions: Diabetic Retinopathy|Posterior Vitreous Detachment|Disease Progression
Interventions: DRUG: ocriplasmin 0.0625mg|DRUG: ocriplasmin 0.125mg|DRUG: Sham injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility of Use of the PATH bCPAP and Oxygen Blenders Device With Neonates in Uganda
Status: COMPLETED
Conditions: Respiratory Distress Syndrome|Infant, Premature
Interventions: DEVICE: bCPAP with blenders
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Board Games Among Mild Cognitive Impairment Patients Experience (GAME Project)
Status: UNKNOWN
Conditions: Cognitive Impairment, Mild
Interventions: BEHAVIORAL: Modern board and card games group|BEHAVIORAL: Paper and pencil tasks group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Lymphadenectomy in Urothelial Carcinoma
Status: SUSPENDED
Conditions: Ureteral Neoplasms
Interventions: PROCEDURE: Lymphadenectomy in conjugation with nephroureterectomy|PROCEDURE: Nephroureterectomy without lymphadenectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Calcaneal Taping on Balance, Gait and Range of Motion in Chronic Stroke Survivors
Status: TERMINATED
Conditions: Chronic Stroke
Interventions: OTHER: Calcaneal taping|OTHER: Sham taping|OTHER: Conventional therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Rituximab and Denileukin Diftitox in Treating Patients With Previously Untreated Stage III or Stage IV Follicular B-Cell Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: BIOLOGICAL: denileukin diftitox|BIOLOGICAL: rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Smoking Cessation Study In Healthy Adolescent Smokers
Status: COMPLETED
Conditions: Smoking Cessation
Interventions: DRUG: Varenicline 1mg BID|DRUG: Varenicline 0.5mg BID|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility of At-Home Telehealth Yoga for Treating Chronic Pain
Status: COMPLETED
Conditions: Chronic Pain|Musculoskeletal Pain
Interventions: COMBINATION_PRODUCT: Teleyoga|BEHAVIORAL: In-person yoga
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Haemodynamic Effects of Apelin Agonists and Antagonists in Man in COPD With Raised Pulmonary Artery Pressures
Status: COMPLETED
Conditions: COPD|Pulmonary Hypertension
Interventions: PROCEDURE: Forearm plethysmography|PROCEDURE: Haemodynamic studies
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Factors Influencing the Human Gut Microbiome Profile in Multi-ethnic Groups of the Singapore Community (FAMES)
Status: COMPLETED
Conditions: Gastroesophageal Reflux Disease
Interventions: DRUG: Omeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Onabotulinumtoxin Type A Reconstitution With Preserved Versus Preservative-free Saline in Chronic Migraine.
Status: COMPLETED
Conditions: Chronic Migraine, Headache
Interventions: DRUG: Preserved saline in reconstitution of Botox
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: CHS Nurses Clinical Competence in Detecting Signs of PPD in Non-Native Speaking Immigrant Mothers'
Status: COMPLETED
Conditions: Depression, Postpartum
Interventions: OTHER: Education in clinical competence in detecting signs of postpartum depression in immigrant mothers
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Combination Chemotherapy in Hodgkin's Disease or Non-Hodgkin's Lymphoma Not Responding to Previous Treatment
Status: COMPLETED
Conditions: Lymphoma
Interventions: DRUG: cisplatin|DRUG: dexamethasone|DRUG: gemcitabine hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of NovoTTF-100A Together With Temozolomide in Newly Diagnosed Glioblastoma Multiforme (GBM)
Status: COMPLETED
Conditions: Glioblastoma Multiforme
Interventions: DEVICE: NovoTTF-100A device|DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BLP25 Liposome Vaccine and Bevacizumab After Chemotherapy and Radiation Therapy in Treating Patients With Newly Diagnosed Stage IIIA or Stage IIIB Non-Small Cell Lung Cancer That Cannot Be Removed by Surgery
Status: COMPLETED
Conditions: Lung Cancer
Interventions: BIOLOGICAL: bevacizumab|BIOLOGICAL: Tecemotide|DRUG: carboplatin|DRUG: cyclophosphamide|DRUG: paclitaxel|RADIATION: radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improving Safety of Diagnosis and Therapy in the Inpatient Setting
Status: COMPLETED
Conditions: Delirium|Confusion|Mental Status Change|Back Pain|Hip Pain Chronic|Chest Pain|Asthma|COPD|Cellulitis|Soft Tissue Infections|Cough|Deep Vein Thrombosis|Pulmonary Embolism|Venous Thromboembolism|Dyspnea|Electrolyte Metabolism Abnormal|Fever|Failure to Thrive|Weakness|Protein-Calorie Malnutrition|Headache|Neck Pain|Hypoxia|Pneumonia|Sepsis|Syncope|Vomiting|Diarrhea|Leg Pain|Abdominal Pain
Interventions: BEHAVIORAL: Diagnostic Uncertainty Educational Curriculum|BEHAVIORAL: Diagnostic Timeout|BEHAVIORAL: Patient Diagnostic (Dx) Questionnaire|BEHAVIORAL: Enhancements to Epic-integrated Quality & Safety Dashboard
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Trial of Gemtuzumab Ozogamicin (GO) in Combination With Zosuquidar in Patients With CD33 Positive Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Leukemia, Myeloid
Interventions: DRUG: Zosuquidar|DRUG: gemtuzumab ozogamicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating the Efficacy and Safety of IV L-Citrulline for the Prevention of Clinical Sequelae of Acute Lung Injury Induced by Cardiopulmonary Bypass in Pediatric Patients Undergoing Surgery for Congenital Heart Defects
Status: RECRUITING
Conditions: Ventricular Septal Defect|Atrioventricular Septal Defect|Primum Atrial Septal Defect
Interventions: DRUG: L-citrulline|DRUG: Plasmalyte A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: dHACM in Lumbar Decompression and Microdiscectomy Surgery
Status: COMPLETED
Conditions: Scarring|Spinal Stenosis|Herniated Disc
Interventions: PROCEDURE: Lumbar Decompression Surgery|PROCEDURE: Microdiscectomy Surgery|OTHER: Dehydrated Human Amnion/Chorion Membrane (dHACM)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Relative Bioavailability and Intra-Subject Variability of Two Lots of E5501 40 mg Tablets Administered Twice as Single Oral Doses to Healthy Subjects
Status: COMPLETED
Conditions: Idiopathic Thrombocytopenia Purpura
Interventions: DRUG: E5501|DRUG: Drug: E5501
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: STRATA: Safe Testing of Risk for AsymptomaTic MicrohematuriA
Status: ACTIVE_NOT_RECRUITING
Conditions: Hematuria|Urothelial Carcinoma
Interventions: DIAGNOSTIC_TEST: Cxbladder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Phenylbutyrate in Treating Patients With Refractory Solid Tumors or Lymphoma
Status: COMPLETED
Conditions: Lymphoma|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: chemotherapy|DRUG: oral sodium phenylbutyrate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Dietary Phosphate Excess on Exercise Capacity and Visceral Adiposity
Status: RECRUITING
Conditions: Physical Inactivity|Phosphate Overload|Visceral Obesity
Interventions: DIETARY_SUPPLEMENT: Sodium Phosphate|DIETARY_SUPPLEMENT: Sodium Chloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Epidural Methadone in Healthy Volunteers
Status: COMPLETED
Conditions: Pain, Acute
Interventions: DRUG: Methadone hydrochloride|DRUG: Morphine Sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Erlotinib, Trastuzumab, and Paclitaxel in Treating Patients With Advanced Solid Tumors
Status: COMPLETED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: paclitaxel|BIOLOGICAL: trastuzumab|DRUG: erlotinib hydrochloride|OTHER: laboratory biomarker analysis|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Controlled Randomised Trial of Ferric Carboxymaltose and Oral Iron to Treat Postpartum Anemia
Status: TERMINATED
Conditions: Anemia, Iron-Deficiency|Puerperal Disorders|Depression, Postpartum
Interventions: DRUG: Ferric carboxymaltose|DRUG: Ferrous sulfate tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Laflavon in Lowering Triglycerides and Raising High-Density Lipoprotein (HDL)
Status: UNKNOWN
Conditions: Metabolic Disease
Interventions: DIETARY_SUPPLEMENT: LaFlavon
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability of Chitosan-N-acetylcysteine Eye Drops in Healthy Young Volunteers
Status: COMPLETED
Conditions: Dry Eye Syndromes
Interventions: DEVICE: Chitosan- N- Acetylcysteine eye drops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Treatment of Patients With Metastatic or Unresectable Gastrointestinal Stromal Tumors in First Line With Nilotinib
Status: ACTIVE_NOT_RECRUITING
Conditions: Gastrointestinal Stromal Tumors
Interventions: DRUG: Nilotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Percutaneous Image Guided Video-Assisted Thoracic Surgery (VATS) Resection of Lung Lesions
Status: COMPLETED
Conditions: Lung Cancer
Interventions: PROCEDURE: Video-Assisted Thoracic Surgery (VATS) wedge resection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of LY2409021 in Participants With Different Levels of Kidney Function
Status: COMPLETED
Conditions: Kidney Failure, Chronic|Renal Insufficiency, Chronic
Interventions: DRUG: LY2409021
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: 89ZrTrastuzumab Breast Imaging With Positron Emission Tomography
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: 89Zr-Trastuzumab Human Dosimetry and Safety|DRUG: HER2 Positive Lesion Detection and Safety
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Dietary Phytoestrogens, Complementary and Alternative Medicine, and Lifestyle in Predicting Survival of Women With Breast Cancer
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: GENETIC: gene expression analysis|GENETIC: polymorphism analysis|OTHER: high performance liquid chromatography|OTHER: laboratory biomarker analysis|OTHER: mass spectrometry|OTHER: questionnaire administration
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: AI-Enhanced Consent for Cataract Surgery
Status: NOT_YET_RECRUITING
Conditions: Cataract
Interventions: BEHAVIORAL: AI-Generated Informative Videos|BEHAVIORAL: Standard Written Information Brochures
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Differential Characteristics of Neuropathy in Type 2 Diabetics With and Without Lower Extremity Wounds
Status: WITHDRAWN
Conditions: Diabetic Foot Ulcer|Diabetic Neuropathy|Type 2 Diabetes
Interventions: PROCEDURE: Diabetic Foot Ulcer Biopsy|OTHER: Survey|OTHER: Comprehensive Neuropathy Assessment|OTHER: Wound Photography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Trial to Evaluate an HIV Envelope Trimer, N332-GT5 gp140, Adjuvanted With SMNP in Adult Participants Without HIV
Status: RECRUITING
Conditions: HIV
Interventions: BIOLOGICAL: N332-GT5 gp140 (IM, Bolus)|BIOLOGICAL: N332-GT5 gp140 (IM, Fractioned)|BIOLOGICAL: N332-GT5 gp140 (SC, Bolus)|BIOLOGICAL: N332-GT5 gp140 (SC, Fractioned)|BIOLOGICAL: SMNP (IM, Bolus)|BIOLOGICAL: SMNP (IM, Fractioned)|BIOLOGICAL: SMNP (SC, Bolus)|BIOLOGICAL: SMNP (SC, Fractioned)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Management of Mild Cognitive Impairment Patients With Greek Mountain Tea - TEAMENTIA
Status: UNKNOWN
Conditions: Mild Cognitive Impairment
Interventions: DIETARY_SUPPLEMENT: 1000+ Greek Mountain Tea|OTHER: Mediterranean Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of Flublok Quadrivalent vs IIV4 in Adults 18-49 Years of Age
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Flublok Quadrivalent|BIOLOGICAL: Inactivated Influenza Vaccine (IIV4)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of Wen Xin Granules for the Treatment of Unstable Angina Pectoris
Status: UNKNOWN
Conditions: Coronary Heart Disease|Unstable Angina|Chinese Herbal Medicine
Interventions: DRUG: Wen Xin granule|DRUG: Clopidogrel Hydrogen Sulfate 75 MG Oral Tablet|DRUG: Atorvastatin Calcium|DRUG: Isosorbide Mononitrate Tab 20 MG|DRUG: Metoprolol Tartrate Tab 25 MG|DRUG: Aspirin Enteric-coated Tablets|DRUG: WXG placebo|DRUG: Trimetazidine Dihydrochloride Tablets|DRUG: glyceryl trinitrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, PK, and PD Study of PGN-EDODM1 in Participants With Myotonic Dystrophy Type 1
Status: RECRUITING
Conditions: Myotonic Dystrophy 1
Interventions: DRUG: PGN-EDODM1|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Diet and Exercise in Patients With Non-Alcoholic Fatty Liver Disease
Status: COMPLETED
Conditions: Fatty Liver
Interventions: BEHAVIORAL: Mod Fat/Low Processed Carb Diet and Moderate Exercise|BEHAVIORAL: Low Fat Diet and Moderate Exercise|BEHAVIORAL: Moderate Exercise Only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bacteria Endotoxin in Peritoneal Dialysis Effluent as a Predictor of Relapsing, Recurrent, and Repeat Peritonitis
Status: COMPLETED
Conditions: Peritoneal Dialysis Associated Peritonitis
Interventions: OTHER: endotoxin assay in peritoneal dialysis effluent
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Prevention Study in Adult Patients Suffering From Migraine Headaches
Status: COMPLETED
Conditions: Migraine Disorders|Migraine
Interventions: DRUG: GSK1838262|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Clinical Trial to Evaluate the Efficacy and Safety of CKD-342
Status: COMPLETED
Conditions: Rhinitis, Allergic, Perennial
Interventions: DRUG: CKD-342|DRUG: Mometasone furoate|DRUG: Levocabastine HCL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dyad Oxytocin Study (DOS)
Status: COMPLETED
Conditions: Schizophrenia|Autism Spectrum Disorder
Interventions: DRUG: Oxytocin|OTHER: Placebo Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Design and Development of a Functional Plant-based Beverage Formulated According to the Main Nutritional Guides for Early Elderly Requirements to Improve Nutritional Status and Immunity for the Early Elderly People to Get Well-healthy Ageing
Status: NOT_YET_RECRUITING
Conditions: Deglutition Disorders
Interventions: OTHER: Sensory test of functional plant-based drink
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Neurostimulation in Temporomandibular Disorders (TMD) Patients
Status: TERMINATED
Conditions: Temporomandibular Joint Disorders
Interventions: DEVICE: Caloric Vestibular Neurostimulation|DEVICE: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 1, First-in-human, Double-blinded, Randomized, Placebo-controlled Trial of a Zika Virus Purified Inactivated Vaccine (ZPIV) With Alum Adjuvant in Healthy Flavivirus-naive and Flavivirus-Primed Subjects.
Status: COMPLETED
Conditions: Zika Virus Infection
Interventions: BIOLOGICAL: IXIARO|OTHER: Placebo|BIOLOGICAL: YF Vax 17D Strain|BIOLOGICAL: Zika Virus Purified Inactivated Vaccine (ZPIV)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Protein Supplementation on Craving in Subjects Hospitalised for Addiction Treatment
Status: NOT_YET_RECRUITING
Conditions: Addiction
Interventions: DIETARY_SUPPLEMENT: protein supplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of High Frequency rTMS on Advancing Parkinson's Disease With Dysphagia
Status: COMPLETED
Conditions: Advanced Parkinson's With Dysphagia
Interventions: PROCEDURE: repetitive transcranial magnetic (rTMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: To Investigate Efficacy, Pharmacodynamics, and Safety of BC 007 in Participants With Long COVID
Status: ACTIVE_NOT_RECRUITING
Conditions: Long Covid
Interventions: DRUG: BC 007 or matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Motexafin Gadolinium Plus Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme
Status: COMPLETED
Conditions: Brain and Central Nervous System Tumors
Interventions: DRUG: motexafin gadolinium|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Registry for Intra-Operative Radiotherapy During Breast Conserving Surgery in Patients With Early Stage Breast Cancer
Status: RECRUITING
Conditions: Early-stage Breast Cancer|Breast Carcinoma in Situ|Breast Neoplasms
Interventions: RADIATION: Intraoperative Radiation Therapy (IORT)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Reverse Innovation and Patient Engagement to Improve Quality of Care and Patient Outcomes
Status: COMPLETED
Conditions: Diabetes|Cardiovascular Disease|Substance Abuse Disorder|Mental Health Disorder
Interventions: OTHER: Co-developed IT intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Effect of Amiloride and Spironolactone in Healthy Persons
Status: COMPLETED
Conditions: High Blood Pressure
Interventions: DRUG: Amiloride|DRUG: Spironolactone|DRUG: Placebo|DRUG: Placebo and spironolactone|DRUG: Spironolactone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment Of Adult Growth Hormone Deficiency After Traumatic Brain Injury
Status: TERMINATED
Conditions: Brain Injuries|Growth Hormone Deficiency
Interventions: DRUG: Genotropin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Functional Improvement and UTC of the Achilles Tendon After Sodium Hyaluronate Injection for Plantaris Syndrome
Status: UNKNOWN
Conditions: Plantaris Friction Syndrome|Non-Insertional Achilles Tendinopathy
Interventions: DRUG: Hyaluronic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Beta-Glucan and Rituximab in Treating Young Patients With Relapsed or Progressive Lymphoma or Leukemia, or Lymphoproliferative Disorder Related to Donor Stem Cell Transplantation
Status: TERMINATED
Conditions: Leukemia|Lymphoma|Lymphoproliferative Disorder
Interventions: BIOLOGICAL: beta-glucan|BIOLOGICAL: rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optical Coherence Tomography Angiography (OCTA) Changes in Patients With Epiretinal Membranes (ERM) With and Without Peeling of the Internal Limiting Membrane (ILM)
Status: COMPLETED
Conditions: Epiretinal Membrane of Both Eyes
Interventions: PROCEDURE: ILM nonpeeling|PROCEDURE: ILM peeling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Twelve Month Long Term Safety Study to Evaluate the Safety of Albuterol in a Dry Powder Inhaler With Both Repeated and as Needed Dosing
Status: TERMINATED
Conditions: Asthma
Interventions: DRUG: Placebo Spiromax|DRUG: Albuterol Spiromax
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Application of Medical Imaging Procedures in Surgery Implanting in Cancerology With the Aim to Reduce Invasive Acts
Status: TERMINATED
Conditions: Upper Digestive Tract Cancer
Interventions: PROCEDURE: Therapeutic assessment -Radio-surgical guidance.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: New Prognostic Index for Neoadjuvant Chemotherapy Outcome in Patients With Advanced High-grade Serous Ovarian Cancer
Status: ENROLLING_BY_INVITATION
Conditions: Ovarian Cancer|Neoadjuvant Chemotherapy|Prognostic Cancer Model
Interventions: DIAGNOSTIC_TEST: CRS scoring|DIAGNOSTIC_TEST: Routine blood laboratory testing before treatment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Treatment of Nonunion of Limb Fracture With Human Amniotic Epithelial Cells（hAECs）
Status: UNKNOWN
Conditions: Nonunion Fracture
Interventions: BIOLOGICAL: Human Amniotic Epithelial Cells|PROCEDURE: debridement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Recombinant hCG to Prevent Breast Cancer in BRCA1 and BRCA2 Carriers
Status: COMPLETED
Conditions: hCG|BRCA1 Mutation|BRCA2 Mutation
Interventions: DRUG: Ovitrelle
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Arnica D1 Ointment After Upper Blepharoplasty
Status: COMPLETED
Conditions: Blepharoplasty|Upper Eyelid Blepharoplasty
Interventions: DRUG: Arnica|DRUG: Placebo ointment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate Safety and Tolerability of TransCon IL-2 β/γ Alone or in Combination With Pembrolizumab and/or Chemotherapy or TransCon TLR7/8 Agonist in Adult Participants With Locally Advanced or Metastatic Solid Tumor Malignancies
Status: RECRUITING
Conditions: Advanced Solid Tumor|Locally Advanced Solid Tumor|Metastatic Solid Tumor|Platinum-resistant Ovarian Cancer|Post Anti-PD-1 Melanoma|2L+ Cervical Cancer|Neoadjuvant Melanoma|Neoadjuvant Non-Small Cell Lung Cancer|Post Anti-PD-(L)1 Non-Small Cell Lung Cancer|Post Anti-PD-(L)1 Small Cell Lung Cancer
Interventions: DRUG: TransCon IL-2 β/γ|DRUG: Pembrolizumab|DRUG: Chemotherapy drug|DRUG: TransCon TLR7/8 Agonist|PROCEDURE: Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective, Multicenter Study of the Second Generation Antimicrobial Graft in the Abdominal Position
Status: UNKNOWN
Conditions: Aneurysmal Disease of the Abdominal Aorta|Occlusive Disease of the Abdominal Aorta
Interventions: DEVICE: Second Generation Anti-Microbial bifurcated vascular graft (InterGard)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment Preference for Weekly Dipeptidyl Peptidase-4 (DPP-4) Inhibitors Versus Daily DPP-4 Inhibitors in Participants With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Trelagliptin|DRUG: Alogliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pharmacy-based Observational Study to Learn More About Iberogast Advance in the Real-world Setting
Status: COMPLETED
Conditions: Functional Gastrointestinal Disorders Such as Irritable Bowel Syndrome and Functional Dyspepsia|Irritable Bowel Syndrome|Functional Dyspepsia
Interventions: DRUG: Iberogast (STW5-II, BAY98-7410)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of ARRY-371797 in Patients With Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: ARRY-371797, p38 inhibitor; oral|DRUG: Placebo; oral
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Phase 2b/3 Study of ABX464 in Moderate to Severe Active Crohn's Disease Patients
Status: WITHDRAWN
Conditions: Crohn Disease
Interventions: DRUG: ABX464|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Gametocytocidal and Transmission-blocking Efficacy of ASAQ and ALAQ With or Without PQ in Mali
Status: COMPLETED
Conditions: Malaria,Falciparum
Interventions: DRUG: Artesunate-amodiaquine combination|DRUG: Primaquine Phosphate|DRUG: Artemether-lumefantrine|DRUG: Amodiaquine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing Patient-Centered Outcomes After Treatment for Uterine Fibroids
Status: COMPLETED
Conditions: Uterine Fibroids
Interventions: PROCEDURE: myomectomy|PROCEDURE: endometrial ablation|PROCEDURE: uterine artery embolization|PROCEDURE: MRI-guided focused ultrasound ablation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of Fibromyalgia With Disease Activity and Clinical Findings in Women With Behçet's Disease
Status: COMPLETED
Conditions: Behcet's Disease|Fibromyalgia
Interventions: DIAGNOSTIC_TEST: fibromyalgia 2013 criteria|OTHER: Behcet's disease current activity form
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Reversing Glucose and Lipid-mediated Vascular Dysfunction
Status: UNKNOWN
Conditions: Blood Pressure|Hypertension
Interventions: DRUG: Dextrose 20 % in 500 ML Injection|DRUG: Intralipid|DRUG: Saline|DRUG: Ascorbic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Micafungin Versus Fluconazole in the Treatment of Invasive Candidiasis and Candidemia
Status: COMPLETED
Conditions: Invasive Candidiasis|Candidemia
Interventions: DRUG: Micafungin|DRUG: fluconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multiple Dose Bioequivalence Study of Pramipexole Extended Release in Chinese Healthy Male Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: pramipexole extended release|DRUG: pramipexole extended release|DRUG: pramipexole immediate release|DRUG: pramipexole immediate release
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Continuous Intraocular Pressure (IOP) Monitoring in Pigmentary Dispersion Syndrome and Pigmentary Glaucoma Patients
Status: TERMINATED
Conditions: Pigmentary Dispersion Syndrome|Pigmentary Glaucoma Patients
Interventions: DEVICE: SENSIMED Triggerfish
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effectivity of 1 Finger Tip Unit Compared to 2 Finger Tip Units 0.05% Tretinoin Cream
Status: UNKNOWN
Conditions: Photoaging
Interventions: DRUG: 0.05% Tretinoin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Proprioceptive Neuromuscular Facilitation (PNF) Technique for Children With Chronic Pulmonary Diseases.
Status: COMPLETED
Conditions: Chronic Respiratory Disease|Cystic Fibrosis|Bronchiectasis
Interventions: BEHAVIORAL: Group applying PNF technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Assessment and Rehabilitation of Central Sensory Impairments for Balance in mTBI
Status: COMPLETED
Conditions: Brain Injury
Interventions: BEHAVIORAL: Vestibular Rehabilitation + audio biofeedback|BEHAVIORAL: Vestibular Rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Epidural Lidocaine on the Pharmacokinetic and Pharmacodynamic Profiles of DepoDur® After Cesarean Delivery
Status: COMPLETED
Conditions: Epidural Analgesia, Obstetric
Interventions: DRUG: DepoDur following epidural lidocaine|DRUG: DepoDur following spinal anesthetic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Ulnar Nerve Entrapment Localization on Ipsilateral Upper Extremity Functions. The Effect of Ulnar Nerve Entrapment Localization on Ipsilateral Upper Extremity Functions. The Effect of Ulnar Nerve Entrapment Localization on Ipsilateral Upper Extremity Functions.
Status: COMPLETED
Conditions: Ulnar Neuropathies
Interventions: DIAGNOSTIC_TEST: EMG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Nasal Tramazoline and Dexamethazone in Obstructive Sleep Apnea (OSA) Patients Tramazoline and
Status: COMPLETED
Conditions: Obstructive Sleep Apnea Syndrome
Interventions: DRUG: Nasal tramazoline with dexamethazone|DRUG: Nasal placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Flixonase Safety in Patients With Allergic Rhinitis (AR)
Status: COMPLETED
Conditions: Rhinitis, Allergic, Perennial
Interventions: DRUG: Intermittent, sub-chronic and chronic Flixonase use|DRUG: Intermittent, sub-chronic and chronic use of intranasal steroids other than Flixonase
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Hemodynamic in Postreperfusion Period and Functional Recovery in Acute Ischemic Stroke Patients
Status: COMPLETED
Conditions: Acute Ischemic Stroke|Intracranial Hemorrhage
Interventions: OTHER: Hemodynamic goal including lower goal of systolic blood pressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Graded Aerobic Exercise in Mild Traumatic Brain Injury
Status: RECRUITING
Conditions: Traumatic Brain Injury|Mild Traumatic Brain Injury
Interventions: OTHER: Graded Aerobic Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Baseline Physiology Studies in Carriers of Gene Variant X Conferring Major Risk of CVD-prone Metabolic Disorders
Status: COMPLETED
Conditions: Hyperlipidemia|Diabetes Mellitus|Metabolic Syndrome|Arterial Hypertension|Obesity
Interventions: OTHER: first phase insulin secretion (FPIR), Hyperinsulinemic euglycemic clamp (HEC), glucose tracer, and palmitate tracer
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: UCAN: Uniting Couples in the Treatment of Anorexia Nervosa
Status: COMPLETED
Conditions: Anorexia Nervosa
Interventions: BEHAVIORAL: CBCT|BEHAVIORAL: Family Supportive Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Patient Controlled Analgesia Pump Cues on Patient Satisfaction
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DEVICE: Patient-Controlled Analgesia pump with Cues|DEVICE: Patient-Controlled Analgesia pump without Cues|DRUG: Morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Ultra-short Glucocorticosteroids and Tocilizumab Therapy in GCA Patients
Status: UNKNOWN
Conditions: GCA|TOCILIZUMAB|Glucocorticoids|PET
Interventions: DRUG: Tocilizumab 162Mg/0.9Ml Autoinjector
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study Comparing Daratumumab, Lenalidomide, and Dexamethasone With Lenalidomide and Dexamethasone in Relapsed or Refractory Multiple Myeloma
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: Daratumumab|DRUG: Lenalidomide|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: OUD (Opioid Use Disorder) Target Trial
Status: NOT_YET_RECRUITING
Conditions: Opioid Use Disorder
Interventions: DEVICE: Active repetitive Transcranial Magnetic Stimulation (rTMS)|DEVICE: Sham repetitive Transcranial Magnetic Stimulation (rTMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Osmolality of Oral Supplements and Ileostomy Output
Status: COMPLETED
Conditions: Ileostomy - Stoma|Short Bowel Syndrome|Sodium Depletion|Nutritional Deficiency
Interventions: DIETARY_SUPPLEMENT: Isoosmolar|DIETARY_SUPPLEMENT: Hyperosmolar
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Sodium Polystyrene Sulfonate in Hyperkalemia
Status: TERMINATED
Conditions: Hyperkalemia
Interventions: DRUG: Sodium polystyrene sulfonate|DRUG: Silicified microcrystalline cellulose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Treatment Patterns and Clinical Outcomes Among Patients Receiving Palbociclib Combinations for Hormone Receptor Positive (HR+)/Human Epidermal Growth Factor Receptor 2 Negative (HER2 ) Advanced/Metastatic Breast Cancer in the Arabian Gulf Region
Status: COMPLETED
Conditions: Breast Neoplasms
Interventions: DRUG: Palbociclib plus an aromatase inhibitor|DRUG: Palbociclib plus fulvestrant
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p