pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Weight Watchers Online 2015
Status: COMPLETED
Conditions: Obesity|Overweight|Body Weight
Interventions: BEHAVIORAL: Weight Watchers Online 2015 Program|OTHER: Electronic Scale with Feedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Self Administered Cognitive Behavior Therapy for Irritable Bowel Syndrome
Status: COMPLETED
Conditions: Irritable Bowel Syndrome
Interventions: BEHAVIORAL: Self Administered Cognitive Behavior Therapy|BEHAVIORAL: Therapist Administered Cognitive Behavior Therapy|BEHAVIORAL: Behavioral Education and Supportive Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neurological Changes With a Memory Self-efficacy Training Protocol
Status: RECRUITING
Conditions: Mild Cognitive Impairment
Interventions: BEHAVIORAL: Memory Self-Efficacy Training|BEHAVIORAL: General Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Assess Safety, Efficacy, Immunogenicity, PK of GC1118 With Combination Chemotherapy
Status: COMPLETED
Conditions: Metastatic Colorectal Cancer|Solid Tumor
Interventions: DRUG: irinotecan|DRUG: FOLFIRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial of ICP-192 in Treated Patients With Advanced Solid Tumors With FGF/FGFR Gene Alterations
Status: RECRUITING
Conditions: Advanced Solid Tumor
Interventions: DRUG: ICP-192
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pre-hospital Anti-fibrinolytics for Traumatic Coagulopathy and Haemorrhage (The PATCH Study)
Status: COMPLETED
Conditions: Wounds and Injuries|Acute Coagulopathy
Interventions: DRUG: Tranexamic Acid|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cognitive-Behavioral Intervention for Worry, Uncertainty, and Insomnia for Cancer Survivors
Status: COMPLETED
Conditions: Anxiety Disorder|Worry|Uncertainty|Sleep Disorders|Insomnia|Fatigue|Pain|Depression|Cognitive-behavioral Therapy|Psychological Intervention|Esophageal Cancer|Pancreatic Cancer|Leukemia|Lung Cancer|Multiple Myeloma|Ovarian Neoplasm|Stage III or IV Cervical or Uterine Cancer|Stage IIIB, IIIC, or IV Breast Cancer|Glioblastoma Multiforme|Relapsed Lymphoma|Stage III or IV Colorectal Cancer|Stage IIIC or IV Melanoma
Interventions: BEHAVIORAL: Cognitive-behavioral therapy for worry, uncertainty & insomnia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Safety, Efficacy and Tolerability Study of Sativex for the Treatment of Spasticity in Children Aged 8 to 18 Years
Status: COMPLETED
Conditions: Cerebral Palsy
Interventions: DRUG: Sativex|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dexamethasone for Excessive Menstruation
Status: COMPLETED
Conditions: Heavy Menstrual Bleeding
Interventions: DRUG: Dexamethasone|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Camrelizumab Combined With Albumin-bound Paclitaxel and Platinum in Neoadjuvant Treatment of Resectable NSCLC
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-small-cell Lung Cancer (NSCLC)
Interventions: DRUG: camrelizumab、albumin-bound paclitaxel and platinum|DRUG: albumin-bound paclitaxel and platinum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Low- Load Strengthening Using Different Exercises Modes During Blood Flow Restriction for Treating Shoulder Impingement Syndrome
Status: RECRUITING
Conditions: Shoulder Impingement Syndrome
Interventions: OTHER: Blood Flow Restriction training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Investigation for Health Efficacy of Infrared-C Radiation on Diabetes Patients in Senior's Activity Center
Status: UNKNOWN
Conditions: Diabetes Mellitus, Type 2
Interventions: DEVICE: FIR-C mattress|DEVICE: FIR-C abdominal pad|DEVICE: fake FIR-C mattress|DEVICE: fake FIR-C abdominal pad
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Adopting a Health-social Partnership Program to Promote Health and Self-care Management Among Older Adults in the Community
Status: RECRUITING
Conditions: Healthy Aging
Interventions: OTHER: Case management|OTHER: Social control call and usual are
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Clinical and Radiographic Assessment of Nano-Bioactive Glass Combined With I-PRF Scaffold in Vital Pulp Treatments in Mandibular Molars With Closed Apices
Status: RECRUITING
Conditions: Vital Pulp Treatment in Mature Permanent Teeth With Irreversible Pulpitis
Interventions: PROCEDURE: Total pulpotomy with I-prf mixed with Nano-bioactive glass
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fluorouracil, Oxaliplatin, and Leucovorin in Treating Patients With Metastatic Stomach Cancer or Gastroesophageal Junction Cancer
Status: COMPLETED
Conditions: Gastric Cancer
Interventions: DRUG: fluorouracil|DRUG: leucovorin calcium|DRUG: oxaliplatin|GENETIC: gene expression analysis|GENETIC: polymorphism analysis|GENETIC: protein expression analysis|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Efficacy and Safety of Indocyanine Green Tracing in 3D Fluorescent Laparoscopic Lymph Node Dissection for Gastric Cancer
Status: NOT_YET_RECRUITING
Conditions: Gastric Cancer
Interventions: PROCEDURE: Preoperative injection of indocyanine green
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of OMEGA3 Supplementation in Diabetic Retinopathy
Status: RECRUITING
Conditions: Diabetic Retinopathy
Interventions: DIETARY_SUPPLEMENT: Nutrof|DIETARY_SUPPLEMENT: Meralut
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Cytogenetic Analysis of Bone Marrow Specimen Prior to High Dose Chemotherapy and Autologous Stem Cell Transplantation in Patients With Non-Hodgkin's Lymphoma or Hodgkin's Disease
Status: COMPLETED
Conditions: Lymphoma, Non-Hodgkin|Hodgkin Disease
Interventions: PROCEDURE: Cytogenetic Analysis of Bone Marrow Specimen
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of Venetoclax and Dinaciclib (MK7965) in Patients With Relapsed/Refractory Acute Myeloid Leukemia
Status: TERMINATED
Conditions: Cancer - Acute Myeloid Leukemia
Interventions: DRUG: Venetoclax|DRUG: Dinaciclib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sustained Lung Inflation and Pulmonary Mechanics in Preterm Infant
Status: WITHDRAWN
Conditions: Preterm Birth|Respiratory Distress Syndrome|Lung Diseases
Interventions: OTHER: Sustained lung inflation|DEVICE: mask using a T-piece system (Fabian,Acutronic Medical Systems AG, Switzerland).
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Improving Health for Patients With Chronic LBP in Rural Communities Through Telerehabilitation
Status: NOT_YET_RECRUITING
Conditions: Chronic Low-back Pain
Interventions: BEHAVIORAL: Educational Control|BEHAVIORAL: Telerehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Ketamine Addition to Lidocaine in Rhinoplasty
Status: COMPLETED
Conditions: Nose Deformities, Acquired
Interventions: DRUG: Lidocaine 2 %|DRUG: Ketamine plus Lidocaine|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Computerized Cognition Testing in Participants With Mild Alzheimer's Disease (AD) Treated With Donepezil (MK-0000-318)
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: Placebo|DRUG: Donepezil|DRUG: Donepezil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Intermittent Versus Continuous Surface O2 During HMP of DCD Kidneys
Status: RECRUITING
Conditions: Delayed Graft Function|Kidney Transplant; Complications|Ischemia Reperfusion Injury|Mitochondrial
Interventions: DRUG: Oxygen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Adalimumab Administered as Subcutaneous Injections in Adult Chinese Rheumatoid Arthritis Subjects Treated With Methotrexate
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: BIOLOGICAL: adalimumab|BIOLOGICAL: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Telemedicine Solution for Remote Support of Rehabilitation, for Patients Undergoing, Total Hip Arthroplasty Surgery
Status: COMPLETED
Conditions: Quality of Life|Anxiety
Interventions: PROCEDURE: remote rehabilitation support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: CPG 7909 in Patients With Cutaneous T-Cell Lymphoma
Status: COMPLETED
Conditions: Lymphoma, T-Cell, Cutaneous
Interventions: DRUG: PF-3512676|DRUG: PF-3512676|DRUG: PF-3512676|DRUG: PF-3512676|DRUG: PF-3512676|DRUG: PF-3512676|DRUG: PF-3512676|DRUG: PF-3512676
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Relamorelin Administered to Participants With Vomiting Symptoms and Moderate to Severe Diabetic Gastroparesis
Status: COMPLETED
Conditions: Diabetes Mellitus|Diabetes Mellitus Complications|Gastroparesis
Interventions: DRUG: Relamorelin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Extension Study to Compare Long-term Efficacy and Safety of Ranibizumab Intravitreal Injections Versus Dexamethasone Intravitreal Implant in Patients With RVO
Status: COMPLETED
Conditions: Retinal Vein Occlusion
Interventions: BIOLOGICAL: RFB002|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mother's Recorded Voice for Preterm Infants
Status: COMPLETED
Conditions: Maternal Depressive Disorder Complicating Childbirth|Preterm Birth|Maternal Anxiety Disorder Complicating Childbirth
Interventions: OTHER: Maternal voice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: In Vivo Treg Expansion and Graft-Versus-Host Disease Prophylaxis
Status: COMPLETED
Conditions: Graft-Versus-Host-Disease
Interventions: DRUG: IL-2|DRUG: Tacrolimus|DRUG: Sirolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: I2PETPG - Imidazoline2 Binding Sites in a Group of Participants Diagnosed With AD
Status: TERMINATED
Conditions: Alzheimer Disease
Interventions: RADIATION: [11C]BU99008|DRUG: Idazoxan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Centre- Versus Home-based Exercise for MCI and Early Dementia
Status: COMPLETED
Conditions: Mild Cognitive Impairment|Dementia
Interventions: BEHAVIORAL: Centre-based exercise|BEHAVIORAL: Home-based exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sunitinib in Treating Young Patients With Refractory Solid Tumors
Status: COMPLETED
Conditions: Central Nervous System Metastases|Childhood Central Nervous System Choriocarcinoma|Childhood Central Nervous System Embryonal Tumor|Childhood Central Nervous System Germ Cell Tumor|Childhood Central Nervous System Germinoma|Childhood Central Nervous System Mixed Germ Cell Tumor|Childhood Central Nervous System Teratoma|Childhood Central Nervous System Yolk Sac Tumor|Recurrent Childhood Central Nervous System Embryonal Tumor|Unspecified Childhood Solid Tumor, Protocol Specific
Interventions: DRUG: sunitinib malate|OTHER: pharmacological study|PROCEDURE: dynamic contrast-enhanced magnetic resonance imaging|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Role of Dexamethasone in Transversus Abdominis Plane Block After Cesarean Section
Status: COMPLETED
Conditions: Cesarean Section
Interventions: DRUG: bupivacaine|DRUG: dexamethasone|DRUG: placebo to dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Vitamin D Supplementation in Wheelchair Indoor Athletes
Status: COMPLETED
Conditions: Vitamin D Deficiency|Spinal Cord Injury|Drug Effects|Dietary Supplements|Physical Education and Training/Methods
Interventions: DIETARY_SUPPLEMENT: Vitamin D|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Meditation Awareness Training for the Treatment of Fibromyalgia Syndrome
Status: COMPLETED
Conditions: Fibromyalgia Syndrome
Interventions: BEHAVIORAL: Meditation Awareness Training|BEHAVIORAL: Cognitive Behavioral Therapy for Groups
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Patient-TAILORed Ablation of Persistent AF Guided by Instantaneous Amplitude and Frequency Modulation Maps (TAILOR-AF)
Status: RECRUITING
Conditions: Persistent Atrial Fibrillation
Interventions: DEVICE: Subcutaneous implantable loop recorder (ILR) implantation|PROCEDURE: Mapping and catheter ablation|PROCEDURE: Minimally invasive surgical ablation via thoracoscopy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Theranostic Implication of Complementary Medicines Against Interleukin Receptors and Gp-130 Proteins
Status: COMPLETED
Conditions: Corona Virus Disease 2019 (COVID-19)
Interventions: DRUG: Tocilizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Placebo-Controlled Study of Auxora for the Extended Treatment of High- Risk Patients With Critical COVID-19 Pneumonia
Status: WITHDRAWN
Conditions: Pneumonia
Interventions: DRUG: Auxora|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Tavo and Pembrolizumab With or Without Chemotherapy in Patients With Inoperable Locally Advanced or Metastatic TNBC
Status: ACTIVE_NOT_RECRUITING
Conditions: Triple Negative Breast Cancer
Interventions: BIOLOGICAL: tavokinogene telseplasmid|BIOLOGICAL: Pembrolizumab|DEVICE: Immunopulse|DRUG: nab paclitaxel|DRUG: gemcitabine plus carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of MabThera (Rituximab) Plus Standard Chemotherapy in Patients With Previously Untreated Mantle Cell Lymphoma.
Status: COMPLETED
Conditions: Mantle Cell Lymphoma
Interventions: DRUG: rituximab [MabThera/Rituxan]|DRUG: First line chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of General Anesthetics on Upper Airway Collapsibility in Healthy Subjects
Status: COMPLETED
Conditions: Airway Complication of Anaesthesia|Healthy
Interventions: DRUG: Propofol|DRUG: Sevoflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of 2 Dosing Regimens of T1225 Eye Drops 1.5% Versus Oral Azithromycin in Treatment of Trachoma
Status: COMPLETED
Conditions: Trachoma
Interventions: DRUG: Azithromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Study of LY3509754 in Healthy Non-Japanese and Japanese Participants
Status: TERMINATED
Conditions: Healthy
Interventions: DRUG: LY3509754|DRUG: Placebo|DRUG: Itraconazole|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Sensor-based Just-in Time Adaptive Interventions (JITAIs) Targeting Eating Behavior
Status: RECRUITING
Conditions: Overweight and Obesity
Interventions: BEHAVIORAL: Eat Less Intervention|BEHAVIORAL: Eat Slower Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: White Button Mushroom Extract in Preventing the Recurrence of Breast Cancer in Postmenopausal Breast Cancer Survivors
Status: COMPLETED
Conditions: Breast Cancer|Cancer Survivor
Interventions: DRUG: white button mushroom extract|OTHER: flow cytometry|OTHER: high performance liquid chromatography|OTHER: laboratory biomarker analysis|OTHER: mass spectrometry|OTHER: pharmacogenomic studies|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adding PD-1 Inhibitor to Neoadjuvant and Adjuvant for NPC
Status: RECRUITING
Conditions: Nasopharyngeal Carcinoma
Interventions: DRUG: PD-1 antibody|DRUG: Gemcitabine|DRUG: Cisplatin|RADIATION: IMRT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Broccoli Sprout Dose Response: Bioavailability and Effects of Air Pollutants
Status: COMPLETED
Conditions: Environmental Carcinogenesis
Interventions: DRUG: Broccoli Sprout-derived Beverage|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Effect of Mat Pilates Exercise on Musculoskeletal System, Body Composition and Psychosocial Status
Status: COMPLETED
Conditions: Healthcare Providers|Health-Related Behavior|Exercise
Interventions: OTHER: mat pilates
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Phase 3 Study to Evaluate Petosemtamab Plus Pembrolizumab vs Pembrolizumab in First-line Treatment of Head and Neck Cancer
Status: RECRUITING
Conditions: Head and Neck Squamous Cell Carcinoma
Interventions: DRUG: Petosemtamab|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of TAK-875 in Combination With Sitagliptin in Participants With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Placebo|DRUG: TAK-875|DRUG: TAK-875|DRUG: Sitagliptin|DRUG: TAK-875 and Sitagliptin|DRUG: TAK-875 and Sitagliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Testing a Self-affirmation Intervention for Use in a Mobile Application
Status: UNKNOWN
Conditions: Smoking|Smoking Cessation|Smoking, Tobacco
Interventions: BEHAVIORAL: Self affirmation, 10 items, written examples|BEHAVIORAL: Self affirmation, 10 items, no examples|BEHAVIORAL: Self affirmation, 10 items, imagined examples|BEHAVIORAL: Self affirmation, 5 items, written examples|BEHAVIORAL: Self affirmation, 5 items, no examples|BEHAVIORAL: Self affirmation, 5 items, imagined examples|BEHAVIORAL: Self affirmation, 3 items, written examples|BEHAVIORAL: Self affirmation, 3 items, no examples|BEHAVIORAL: Self affirmation, 3 items, imagined examples
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Survey Evaluating the Psychosocial Effects of Living With Haemophilia
Status: COMPLETED
Conditions: Congenital Bleeding Disorder|Haemophilia A|Haemophilia B|Haemophilia A With Inhibitors|Haemophilia B With Inhibitors|Relatives to/Carers of Patients
Interventions: OTHER: No treatment given
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety Study of Autologous Dendritic Cells Injected Into the Prostate After Cryoablation for Advanced Prostate Cancer
Status: TERMINATED
Conditions: Prostate Cancer
Interventions: BIOLOGICAL: VDC2008|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Quantification of Estradiol's Impact on Nucleotides in Cellular Populations of the Lower GI Tract
Status: COMPLETED
Conditions: HIV/AIDS
Interventions: DRUG: Tenofovir 300Mg Oral Tablet|DRUG: Emtricitabine 200 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Jaw Clenching on Anaerobic Ability and Ventilatory Flows
Status: COMPLETED
Conditions: Mouth Breathing
Interventions: DEVICE: Mouthguard|DEVICE: No mouthguard
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety and Efficacy Study of PEA and Polydatin on Intestinal Inflammation and Visceral Hyperalgesia in IBS Patients
Status: UNKNOWN
Conditions: Irritable Bowel Syndrome
Interventions: DIETARY_SUPPLEMENT: Recoclix|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of a Virtual Education-Based Transition Intervention to Improve Transition Readiness in Adolescent and Young Adults With Congenital Adrenal Hyperplasia
Status: RECRUITING
Conditions: Congenital Adrenal Hyperplasia
Interventions: OTHER: virtual educational based transition intervention self-paced
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of Apnea Tolerance in Two Positions of Patients With BMI 30-40
Status: COMPLETED
Conditions: General Surgery
Interventions: OTHER: 25° head-up position|OTHER: 55° head-up position
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: His-Bundle Corrective Pacing in Heart Failure
Status: RECRUITING
Conditions: Right Bundle-Branch Block|Heart Failure|His-bundle Pacing|Cardiac Resynchronization Therapy
Interventions: PROCEDURE: His-CRT implantation|PROCEDURE: BIV-CRT implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Chronic Consumption of Vinegar on Visceral Adiposity in Overweight Adults (VAnish)
Status: TERMINATED
Conditions: Body Composition
Interventions: DIETARY_SUPPLEMENT: Study Beverage Consumption
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Chemotherapy for Obstructive Colon cancER First Treated by cOlostomy
Status: NOT_YET_RECRUITING
Conditions: Colon Cancer
Interventions: DRUG: Neoadjuvant chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nab-Paclitaxel and Bevacizumab or Ipilimumab as First-Line Therapy in Treating Patients With Stage IV Melanoma That Cannot Be Removed by Surgery
Status: COMPLETED
Conditions: Metastatic Melanoma|Mucosal Melanoma|Stage IV Cutaneous Melanoma AJCC v6 and v7|Stage IV Uveal Melanoma AJCC v7|Unresectable Melanoma
Interventions: BIOLOGICAL: Bevacizumab|BIOLOGICAL: Ipilimumab|OTHER: Laboratory Biomarker Analysis|DRUG: Nab-paclitaxel|OTHER: Pharmacological Study
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study in Healthy People to Test How Combining BI 1467335 and Tyramine Affects Blood Pressure
Status: TERMINATED
Conditions: Healthy
Interventions: DRUG: BI 1467335|DRUG: Placebo|DRUG: Phenelzine sulfate|DRUG: Tyramine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Two Different Management Techniques for Extensive Molar Defects in Patients Suffering From MIH
Status: COMPLETED
Conditions: Molar Incisor Hypomineralization
Interventions: DEVICE: CAD-CAM milled PMMA crown|OTHER: Cast metal coping using nickel chromium alloy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of GlideScope Specific Stylet to Malleable Stylet for GlideScope Intubation
Status: COMPLETED
Conditions: Intubation, Endotracheal
Interventions: DEVICE: GlideScope Specific Stylet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Unlocking Dystonia From Parkinson's Disease With Directional DBS Technology
Status: COMPLETED
Conditions: Dystonia-Parkinsonism, Adult-Onset|Parkinson Disease
Interventions: DEVICE: Boston Scientific Vercise PC IPG with directional DBS lead
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Near-infrared Transcranial Laser Therapy in Subjects With Major Depressive Disorder: A Study of Dosing With Laser
Status: UNKNOWN
Conditions: Major Depressive Disorder
Interventions: DEVICE: Near-infrared Transcranial Laser Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Post Market Non-Inferiority Study Comparing Triojection® to Discectomy for Lumbar Disc Herniation
Status: UNKNOWN
Conditions: Lumbar Disc Herniation
Interventions: DEVICE: Triojection|PROCEDURE: Surgical discectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Attention Disengagement Training for Social Phobia
Status: COMPLETED
Conditions: Social Anxiety Disorder
Interventions: BEHAVIORAL: Attention Disengagement Training (ADT)|BEHAVIORAL: Placebo Condition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Driving Pressure-guided Lung Protective Ventilation
Status: RECRUITING
Conditions: Hypoxemia|Ventilator Lung
Interventions: PROCEDURE: Driving pressure-guided positive end expiratory pressure|PROCEDURE: Optimal oxygenation-guided positive end expiratory pressure|PROCEDURE: Ventilation strategy|PROCEDURE: Management of hypoxemia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Nivolumab and Azacitidine With or Without Ipilimumab in Treating Patients With Refractory/Relapsed or Newly Diagnosed Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Acute Bilineal Leukemia|Acute Biphenotypic Leukemia|Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome|Chronic Myelomonocytic Leukemia|Myelodysplastic Syndrome|Recurrent Acute Myeloid Leukemia|Refractory Acute Myeloid Leukemia|Secondary Acute Myeloid Leukemia|Therapy-Related Acute Myeloid Leukemia
Interventions: DRUG: Azacitidine|BIOLOGICAL: Ipilimumab|OTHER: Laboratory Biomarker Analysis|BIOLOGICAL: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety and EffIcacy of PRX-102 on Gastrointestinal Symptoms in Naïve Fabry Disease
Status: WITHDRAWN
Conditions: Fabry Disease
Interventions: BIOLOGICAL: PRX-102|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Angulus on Patient-elevation Compliance
Status: COMPLETED
Conditions: Ventilator Adverse Event|Ventilator Associated Pneumonia|Hospital Acquired Condition|Hospital-acquired Pneumonia|Recumbency|Head-of-bed
Interventions: DEVICE: Angulus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Phase I/II Study of Carfilzomib, Pomalidomide and Dexamethasone in Relapsed And/Or Refractory Multiple Myeloma Patients (CPD)
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Carfilzomib|DRUG: Pomalidomide|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: L-carnitine and COH in PCOS Women Undergoing IVF/ICSI Cycles
Status: COMPLETED
Conditions: Polycystic Ovary Syndrome
Interventions: DRUG: L-carnitine 1000 Mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Muscle Fatigue and a Taping Technique on Shoulder Motion of Athletes
Status: UNKNOWN
Conditions: Shoulder Injury|Muscle Fatigue
Interventions: OTHER: Elastic taping applied with tension|OTHER: Elastic taping applied without tension|OTHER: Fatigue protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Prospective Observational Study on SEBBIN Silicone Gel-filled Testicular Implants
Status: RECRUITING
Conditions: Testicular Cancer|Testicular Torsion|Gender Dysphoria|Undescended Testes|Orchitis|Testicular Agenesis|Testicular Atrophy|Prosthesis Durability
Interventions: DEVICE: Placement of testicular prosthesis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Molecular Effects of Apremilast in the Synovium of Psoriatic Arthritis Patients
Status: COMPLETED
Conditions: Psoriatic Arthritis
Interventions: PROCEDURE: Global gene expression profiles obtained from synovial biopsies.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Dietary Management of Gestational Diabetes Mellitus
Status: NOT_YET_RECRUITING
Conditions: Gestational Diabetes Mellitus in Pregnancy|Diet|Healthy
Interventions: BEHAVIORAL: diet management program based on the nudge strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Biological Therapy in Treating Patients With Advanced Myelodysplastic Syndrome, Acute or Chronic Myeloid Leukemia, or Acute Lymphoblastic Leukemia Who Are Undergoing Stem Cell Transplantation
Status: COMPLETED
Conditions: Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities|Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)|Adult Acute Myeloid Leukemia With t(15;17)(q22;q12)|Adult Acute Myeloid Leukemia With t(16;16)(p13;q22)|Adult Acute Myeloid Leukemia With t(8;21)(q22;q22)|B-cell Adult Acute Lymphoblastic Leukemia|B-cell Childhood Acute Lymphoblastic Leukemia|Childhood Chronic Myelogenous Leukemia|Childhood Myelodysplastic Syndromes|Chronic Myelomonocytic Leukemia|Essential Thrombocythemia|Polycythemia Vera|Previously Treated Myelodysplastic Syndromes|Recurrent Adult Acute Lymphoblastic Leukemia|Recurrent Adult Acute Myeloid Leukemia|Recurrent Childhood Acute Lymphoblastic Leukemia|Recurrent Childhood Acute Myeloid Leukemia|Refractory Anemia With Excess Blasts|Refractory Anemia With Excess Blasts in Transformation|Relapsing Chronic Myelogenous Leukemia|Secondary Acute Myeloid Leukemia|T-cell Adult Acute Lymphoblastic Leukemia|T-cell Childhood Acute Lymphoblastic Leukemia
Interventions: BIOLOGICAL: therapeutic allogeneic lymphocytes|BIOLOGICAL: aldesleukin|PROCEDURE: peripheral blood stem cell transplantation|PROCEDURE: allogeneic bone marrow transplantation|OTHER: laboratory biomarker analysis|GENETIC: gene expression analysis|OTHER: immunologic technique|OTHER: flow cytometry|GENETIC: polymerase chain reaction|GENETIC: cytogenetic analysis|OTHER: staining method
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sentinel Node Detection With Technetium-99m Albumin Nanocolloid and ICG in Patients With Epithelial Ovarian Cancer
Status: NOT_YET_RECRUITING
Conditions: Ovarian Epithelial Cancer
Interventions: DIAGNOSTIC_TEST: 99mTC nanocolloid albumin injection|DIAGNOSTIC_TEST: ICG injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Ribociclib and Everolimus in Treating Children With Recurrent or Refractory Malignant Brain Tumors
Status: COMPLETED
Conditions: CNS Embryonal Tumor, Not Otherwise Specified|Malignant Glioma|Recurrent Atypical Teratoid/Rhabdoid Tumor|Recurrent Childhood Ependymoma|Recurrent Diffuse Intrinsic Pontine Glioma|Recurrent Medulloblastoma|Refractory Diffuse Intrinsic Pontine Glioma
Interventions: DRUG: Everolimus|OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacological Study|DRUG: Ribociclib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Xuesaitong Soft Capsules on Major Risk Factors in Patients With Coronary Heart Disease
Status: NOT_YET_RECRUITING
Conditions: Coronary Heart Disease
Interventions: DRUG: Xuesaitong Soft Capsule|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Hyaluronic Acid Filler IMD1 Basic for Correction of Nasolabial Folds
Status: COMPLETED
Conditions: Nasolabial Folds
Interventions: DRUG: Hyaluronic acid filler/IMD1 basic
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Project AWARE: Using the Emergency Department (ED) to Prevent Sexually Transmitted Infections (STIs) in Youth
Status: WITHDRAWN
Conditions: Chlamydia|Gonorrhea|HIV
Interventions: BEHAVIORAL: HIV testing|BEHAVIORAL: STI/HIV-T|BEHAVIORAL: STI/HIV-Plus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Effect of Virtual Reality in Spider Cage on Gross Motor Performance and Balance in Children With Spastic Diplegia
Status: COMPLETED
Conditions: Cerebral Palsy
Interventions: DEVICE: virtual reality glasses|OTHER: The traditional exercise program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Pharmacokinetics Investigation of Stimotimagene Copolymerplasmid
Status: COMPLETED
Conditions: Sarcoma|Melanoma|Squamous Cell Carcinoma of Head and Neck|Breast Neoplasms|Uterine Cervical Neoplasms|Vulvar Neoplasms|Penile Neoplasms|Anus Neoplasms
Interventions: BIOLOGICAL: Stimotimagene copolymerplasmid|DRUG: Ganciclovir
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Augmented Reality in Minimally Invasive Surgery
Status: UNKNOWN
Conditions: Laparoscopic Hepatectomy|Laparoscopic Liver Thermal Ablation
Interventions: DEVICE: LapAR
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: PercutaNEOus Coronary Intervention Followed by Monotherapy INstead of Dual Antiplatelet Therapy in the SETting of Acute Coronary Syndromes: The NEO-MINDSET Trial
Status: RECRUITING
Conditions: Acute Coronary Syndrome
Interventions: DRUG: Antiplatelet Monotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PFLL Combined With PD-1 Antibody With or Without FMT for Oligometastatic NPC,a Phase III ,Open, Randomized Clinical Trial.
Status: NOT_YET_RECRUITING
Conditions: Nasopharyngeal Carcinoma
Interventions: DRUG: Intestinal bacteria freeze-dried powder capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Alvocidib in Patients With Relapsed/Refractory AML Following Treatment With Venetoclax Combination Therapy
Status: TERMINATED
Conditions: Acute Myeloid Leukemia (AML)
Interventions: DRUG: Alvocidib (flavopiridol) and cytarabine (Ara-C)|DRUG: Alvocidib (flavopiridol)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Creatine Supplementation and Cognition
Status: COMPLETED
Conditions: Cognition|Aging
Interventions: DIETARY_SUPPLEMENT: creatine supplementation|OTHER: Placebo (Dextrose)|OTHER: Resistance training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Efficacy of Plastic Stent Anchoring to Reduce Migration of Metal Stent
Status: COMPLETED
Conditions: Malignant Biliary Stricture
Interventions: PROCEDURE: Plastic stent anchoring|PROCEDURE: FCSEMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Healthynsect Child Growth and Health Intervention Study
Status: RECRUITING
Conditions: Nutrition Status
Interventions: DIETARY_SUPPLEMENT: CSB+|DIETARY_SUPPLEMENT: Enriched nutrition food (CEF)|BEHAVIORAL: Nutrition education|COMBINATION_PRODUCT: Combined nutrition and education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Surgery or Lifestyle With Intensive Medical Management in the Treatment of Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus|Obesity
Interventions: DEVICE: Allergan Adjustable Gastric Band Surgery|OTHER: Intensive Medical Diabetes & Weight Management (Why WAIT) - Band Group|PROCEDURE: Roux-en-Y Gastric Bypass (RYGB) Surgery|OTHER: Intensive Medical Diabetes & Weight Management (Why WAIT) - Bypass Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Botulinum Toxin A as Treatment for Chronic Postsurgical Pain Following Lung Cancer Surgery
Status: UNKNOWN
Conditions: Chronic Pain|Post-thoracotomy Pain Syndrome|Pain, Neuropathic|Pain, Postoperative
Interventions: DRUG: Onabotulinum Toxin A|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Effect of Tocilizumab on Signs and Symptoms in Patients With Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: tocilizumab [RoActemra/Actemra]
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exercise Capacity Under Various FiO2 and Oxygen Flow Rates Using HFNC
Status: COMPLETED
Conditions: High-flow Nasal Cannula|Exercise Capacity|Respiratory Failure
Interventions: DEVICE: High-flow nasal cannula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Investigation of the Effects of Medium Cut-off Dialyzers Versus High-Flux Dialyzers on Clinical and Laboratory Parameters of Prevalent Hemodialysis Patients
Status: COMPLETED
Conditions: Hemodialysis-Associated Pruritus|Malnutrition-Inflammation-Cachexia Syndrome|Restless Legs Syndrome|Anemia of Chronic Kidney Disease|Depressive Disorder
Interventions: DEVICE: Dialysis using the Theranova-400 device.|DEVICE: Dialysis using the FX80 device.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of C1 Inhibitor (Human) for the Prevention of Angioedema Attacks and Treatment of Breakthrough Attacks in Japanese Subjects With Hereditary Angioedema (HAE)
Status: COMPLETED
Conditions: Hereditary Angioedema (HAE)
Interventions: DRUG: CINRYZE 500 U|DRUG: CINRYZE 1000 U
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot and Feasibility Study of the Imaging Potential of EC17: Intraoperative Folate-fluorescein Conjugate (EC17) Lung Cancer (CA)
Status: COMPLETED
Conditions: Lung and Pleural Malignancies|Neoplasms|Nodules|Adenocarcinoma
Interventions: DRUG: EC17 imaging contrast agent
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: BeEAC Conditioning Regimen in Malignant Lymphoma Subjects With Indications to Autologous Hematopoietic Stem-cell Transplantation
Status: UNKNOWN
Conditions: Relapsed/Refractory Malignant Lymphomas
Interventions: DRUG: Bendamustine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Acute Ischemic STroke With Edaravone Dexborneol II (TASTE-2)
Status: COMPLETED
Conditions: Acute Ischemic Stroke|Mechanical Thrombectomy|Edaravone Dexborneol|Phase III
Interventions: DRUG: Edaravone Dexborneol Concentrated Solution for injection|DRUG: Edaravone Dexborneol placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Efficacy, Pharmacokinetics and Safety of Continuous Intravenous Infusion of Org 9426 (Study P05977)
Status: COMPLETED
Conditions: Anesthesia
Interventions: DRUG: Rocuronium bromide|DRUG: Rocuronium bromide|DRUG: Rocuronium bromide|DRUG: Sevoflurane|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tacrolimus and MMF as Post Grafting Immunosuppression After Conditioning With Flu TBI for HLA Matched Family Donor
Status: UNKNOWN
Conditions: Multiple Myeloma|Lymphoma|Acute Myelogenous Leukemia|Acute Lymphocytic Leukemia|Myelodysplastic Syndrome
Interventions: DRUG: Tacrolimus and MMF
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Symptom-Related Cytokines in Acute Myeloblastic Leukemia and Myelodysplastic Syndrome Patients
Status: COMPLETED
Conditions: Myelodysplastic Syndrome|Acute Myeloblastic Leukemia|Leukemia
Interventions: BEHAVIORAL: Questionnaire
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Long-term Study of Lemborexant in Insomnia Disorder (SUNRISE 2)
Status: COMPLETED
Conditions: Insomnia Disorder
Interventions: DRUG: lemborexant|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Three Different Initial Treatments Without Protease Inhibitors for HIV Infection
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Abacavir sulfate, Lamivudine and Zidovudine|DRUG: Atazanavir|DRUG: Lamivudine/Zidovudine|DRUG: Abacavir sulfate|DRUG: Efavirenz|DRUG: Nevirapine|DRUG: Lamivudine|DRUG: Stavudine|DRUG: Zidovudine|DRUG: Didanosine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT