pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Whole Brain Radiotherapy With or Without Temozolomide at Daily Fixed-dose for Brain Metastases Treatment
Status: COMPLETED
Conditions: Brain Neoplasms
Interventions: DRUG: Temozolomide|RADIATION: Whole brain irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Analgesic Efficacy and Safety of V116517 in Subjects With Moderate to Severe Chronic Pain Due to Osteoarthritis (OA) of the Knee
Status: COMPLETED
Conditions: Osteoarthritis, Knee|Pain
Interventions: DRUG: V116517 50-mg tablets|DRUG: V116517 30-mg tablets|DRUG: Naproxen 500-mg capsules|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Esophagogastroduodenoscopy (EGD) is an Aerosol-generating Procedure: Proof of Concept Study
Status: UNKNOWN
Conditions: Aerosol-generating Procedure, Esophagogastroduodenoscopy
Interventions: OTHER: No intervention, observational study
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Small Bowel Capsule Endoscopy Findings in Patients Receiving Cellcept®
Status: COMPLETED
Conditions: Gastrointestinal Lesions|Signs and Symptoms, Digestive
Interventions: PROCEDURE: Small bowel capsule endoscopy (SBCE)|DRUG: myfortic
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Depth of Sedation and Its Impact on Cerebrovascular Reactivity in Acute Respiratory Distress Syndrome: A Pilot Analysis
Status: NOT_YET_RECRUITING
Conditions: ARDS, Human
Interventions: DEVICE: Masimo O3 NIRS cerebral oximetry and SedLine processed EEG
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Chromoendoscopy for Serrated Polyposis Syndrome
Status: COMPLETED
Conditions: Colonic Polyp|Colonic Neoplasms|Colonic Cancer
Interventions: DEVICE: chromoendoscopy with indigo carmine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of Continuous Subcutaneous Insulin Infusion (CSII) Pump Function in Subjects With Type 1 Diabetes With Recombinant Human Hyaluronidase (rHuPH20)
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus
Interventions: DRUG: Rapid Acting insulin with pre-treatment of rHuPH20|DEVICE: Sham injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Helicobacter Pylori Eradication on Proteinuria in Patients With Membranous Nephropathy
Status: COMPLETED
Conditions: Nephrotic Syndrome|Glomerulonephritis|Membranous Nephropathy
Interventions: DRUG: lansoprazole, amoxicillin, clarithromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The National Diabetes Prevention Program in Rural Communities
Status: COMPLETED
Conditions: PreDiabetes|Weight Loss|Lifestyle Risk Reduction
Interventions: BEHAVIORAL: Diabetes Prevention Program-Remote (DPP-R)|BEHAVIORAL: Diabetes Prevention Program-Facebook (DPP-FB)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Effects of Stabilization-based Pilates Exercise on Gait and Balance in Women With Flexible Pesplanus
Status: COMPLETED
Conditions: Flexible Flatfoot
Interventions: BEHAVIORAL: core-lower extremity Pilates Training Group|OTHER: Non-Training Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Compare the Efficacy and Safey of Vildagliptin Compared to Voglibose in Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Vildagliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of Motivational Interviewing in Reducing the Use of Household Chemicals and Personal Care Products During Pregnancy
Status: COMPLETED
Conditions: Motivational Interview|Cosmetic Product Causing Toxic Effect
Interventions: BEHAVIORAL: Experimental group- Motivational Interview
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Efficacy and Safety Study of SHP647 as Induction Therapy in Participants With Moderate to Severe Ulcerative Colitis
Status: TERMINATED
Conditions: Ulcerative Colitis
Interventions: DRUG: Ontamalimab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of 6 Weeks High-intensity Interval Training Among Spinal Cord Injury
Status: COMPLETED
Conditions: INCOMPLETE SPINAL CORD INJURY (ASIA D)
Interventions: OTHER: Functional Electrical Stimulation Leg Cycling Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Oral Prednisone in Improving Physical Functioning and Decreasing Pain in People With Sciatica
Status: COMPLETED
Conditions: Sciatica
Interventions: DRUG: Prednisone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy Assessment of Two Antibiotic Prophylaxis Regimens in Oral and Maxillofacial Trauma Surgery
Status: UNKNOWN
Conditions: Facial Fractures
Interventions: PROCEDURE: Cefazolin|PROCEDURE: Cefazolin Single Dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Stereotactic Body Radiotherapy and Concurrent Cisplatin for Re-Irradiation of Unresectable, Recurrent Squamous Cell Carcinomas of Head and Neck
Status: COMPLETED
Conditions: Squamous Cell Carcinoma of the Head and Neck
Interventions: DRUG: Cisplatin|RADIATION: Stereotactic Body Radiation Therapy (SBRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Therapy for Children With Advanced Stage Neuroblastoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Neuroblastoma
Interventions: DRUG: cyclophosphamide|DRUG: topotecan|BIOLOGICAL: hu14.18K322A|PROCEDURE: peripheral blood stem cell harvest|PROCEDURE: surgical resection|DRUG: cisplatin|DRUG: etoposide|DRUG: doxorubicin|DRUG: vincristine|DRUG: busulfan|DRUG: melphalan|BIOLOGICAL: peripheral blood stem cell transplantation|BIOLOGICAL: natural killer cell infusion|RADIATION: radiation therapy|BIOLOGICAL: GM-CSF|BIOLOGICAL: G-CSF|DRUG: mesna|DRUG: levetiracetam|BIOLOGICAL: interleukin-2|DRUG: Isotretinoin|DEVICE: CliniMACS
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Efficacy of TNF-Kinoid in Patients With Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: BIOLOGICAL: TNF-Kinoid|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Innovative Pulmonary Solutions (IPS) System for Targeted Lung Denervation
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: DEVICE: TLD Therapy (IPS SystemTM)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intraventricular Stasis In Cardiovascular Disease
Status: RECRUITING
Conditions: Dilated Cardiomyopathy|Thrombosis Cardiac|Stroke|Hypertrophic Cardiomyopathy
Interventions: DIAGNOSTIC_TEST: Doppler echocardiogram exam|DIAGNOSTIC_TEST: Cardiac magnetic resonance|DIAGNOSTIC_TEST: Brain magnetic resonance|DIAGNOSTIC_TEST: Coagulation blood test|DIAGNOSTIC_TEST: Holter monitoring
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: ESP Versus TEA for Oeasophagus Cancer Surgery
Status: NOT_YET_RECRUITING
Conditions: Peri Operative Analgesia
Interventions: PROCEDURE: Thoracic epidurale|PROCEDURE: Erector spinae block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Long-term Safety Study of Adjunctive Troriluzole in Subjects With Obsessive Compulsive Disorder
Status: ENROLLING_BY_INVITATION
Conditions: Obsessive Compulsive Disorder
Interventions: DRUG: Troriluzole (BHV-4157)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of RPH-104 Treatment in Patients With Recurrent Pericarditis
Status: NOT_YET_RECRUITING
Conditions: Recurrent Pericarditis
Interventions: BIOLOGICAL: RPH-104|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Graz Study on the Risk of Atrial Fibrillation
Status: UNKNOWN
Conditions: Atrial Fibrillation|Hypertension|Diabetes|Chronic Heart Failure|Vascular Disease
Interventions: DEVICE: Medtronic Reveal XT implantable loop recorder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study on the Tailored Intervention Strategy of Childhood Obesity Based on Monitoring Physical Activities and Dietary Behaviors
Status: COMPLETED
Conditions: Pediatric Obesity
Interventions: BEHAVIORAL: Monitoring and Tailored prescription|BEHAVIORAL: Happy 10 program|BEHAVIORAL: Specified nutrition education|BEHAVIORAL: General Health Education
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Efficacy of Silymarin as Adjuvant Therapy on Colorectal Cancer Patients Undergoing FOLFIRI Treatment
Status: COMPLETED
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: Silymarin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of PEDALS Program Versus Lower Limb Strength Training in Diplegic CP
Status: COMPLETED
Conditions: Cerebral Palsy,Diplegic
Interventions: OTHER: Pediatric Endurance and Limb Strengthening Program (PEDALS) and Lower Limb Strength Training|OTHER: Lower Limb Strength Training Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Donor Stem Cell Transplant or Bone Marrow Transplant in Treating Patients With Acute Myeloid Leukemia in Remission
Status: COMPLETED
Conditions: Leukemia
Interventions: BIOLOGICAL: anti-thymocyte globulin|DRUG: busulfan|DRUG: cyclophosphamide|DRUG: cyclosporine|DRUG: fludarabine phosphate|DRUG: methotrexate|PROCEDURE: allogeneic hematopoietic stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Group-based Training for Parents of Children With Dyslexia
Status: UNKNOWN
Conditions: Dyslexia|Reading Disorder|Reading Disability|Developmental Reading Disorder
Interventions: BEHAVIORAL: parent training (dyslexia)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tofogliflozin GLP-1 Analogue Combination Trial
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Tofogliflozin|DRUG: GLP-1 analogue
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of DBPR108 and Metformin Hydrochloride Combination Therapy in Patients With T2DM
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: DBPR108|DRUG: metformin hydrochloride|DRUG: placepo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Increasing Men's Engagement in Preventive Healthcare Through an Enhanced Cocoon Vaccination Strategy
Status: NOT_YET_RECRUITING
Conditions: Vaccines|Preventive Medicine
Interventions: OTHER: Information Sheet|OTHER: High-touch connect
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Efficacy of Platelet Rich Plasma in Plantar Fasciitis
Status: COMPLETED
Conditions: Plantar Fascitis
Interventions: BIOLOGICAL: Injection of autologous platelet rich plasma|DRUG: Injection of cortivazol : Altim®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: (Phosphodiesterase 5 Inhibitors & α-blockers): Single Versus Combined Therapy in Benign Prostatic Hyperplasia
Status: UNKNOWN
Conditions: Benign Prostatic Hyperplasia
Interventions: DRUG: Phosphodiesterase 5 Inhibitors|DRUG: Alpha Blockers|DRUG: Combined Alpha Blockers and Phosphodiesterase 5 Inhibitors
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intrathecal Dexmedetomidine vs Midazolame
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: Dexmedetomidine|DRUG: Midazolam|DRUG: Bupivacain
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of Hand Massage on the Pain of Cardiac Surgery Critically Ill
Status: UNKNOWN
Conditions: Pain
Interventions: OTHER: hand massage|OTHER: hand holding|OTHER: application of unscented hypoallergenic cream|OTHER: environmental adjustments
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Japanese Study Evaluating the Effects of Telithromycin in Children With Acute Otitis Media
Status: COMPLETED
Conditions: Otitis Media
Interventions: DRUG: Telithromycin (HMR3647)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Test Combination Treatments in Participants With Advanced Gastric Cancer
Status: COMPLETED
Conditions: Advanced Gastric Cancer
Interventions: BIOLOGICAL: Nivolumab|BIOLOGICAL: Ipilimumab|BIOLOGICAL: Relatlimab|BIOLOGICAL: BMS-986205|DRUG: Rucaparib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adaptive RadioTherapy for OroPharynx Cancer
Status: RECRUITING
Conditions: Oropharynx Cancer|Radiotherapy; Complications|Radiotherapy Side Effect|Dysphagia|MRI
Interventions: RADIATION: Standard radiotherapy +/- chemotherapy|RADIATION: Experimental radiotherapy +/- chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effectiveness and Safety of GAL1906 for Correction of Wrinkles in the décolletage Area
Status: COMPLETED
Conditions: Wrinkle
Interventions: DEVICE: GAL1906
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial to Evaluate Safety and Efficacy of GM-CSF /Sargramostim in Down Syndrome
Status: RECRUITING
Conditions: Down Syndrome
Interventions: DRUG: Sargramostim for Injection|DRUG: Saline Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Antiproteinuric Effect of Imidapril Versus Ramipril in Type 2 Diabetic and Hypertensive Patients With Microalbuminuria
Status: UNKNOWN
Conditions: Hypertension|Type 2 Diabetes Mellitus|Microalbuminuria
Interventions: DRUG: Ramipril|DRUG: Imidapril
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dupilmuab for Atopic Dermatitis Monitored With Noninvasive Imaging.
Status: UNKNOWN
Conditions: Eczema|Atopic Dermatitis
Interventions: DRUG: Dupilumab|DEVICE: Optical Coherence Tomography|DEVICE: Reflectance confocal microscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cell Free DNA Quantification in Patients With Endometriosis Followed Witd Medical Assistance to Procreation
Status: COMPLETED
Conditions: Endometriosis|Cell Free DNA
Interventions: BIOLOGICAL: blood sample
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Early Versus Traditional Oral Hydration After Cesarean Section
Status: COMPLETED
Conditions: Gastrointestinal Motility and Defecation Conditions
Interventions: OTHER: Early Hydration|OTHER: Traditional Oral Hydration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pgp Transporter and CNS Biodistribution of Ondansetron in Healthy Volunteers
Status: TERMINATED
Conditions: Neuropathic Pain
Interventions: DRUG: Ondansetron 8mg with Saline & Tariquidar|DRUG: Ondansetron 16mg with Saline & Tariquidar
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: LI-ESWT Versus Sham Therapy in Men With ED
Status: NOT_YET_RECRUITING
Conditions: Erectile Dysfunction
Interventions: DEVICE: Low-intensity Extracorporeal Shockwave Therapy|DEVICE: Sham Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Lazanda Fentanyl Nasal Spray Pre Radiofrequency Nerve Ablations(RFA) of Lumbar Facet Joints
Status: COMPLETED
Conditions: Minor Procedural Pain
Interventions: DRUG: Lazanda
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Cohesive Bandage on Axillary Web Syndrome After
Status: RECRUITING
Conditions: Axillary Web Syndrome
Interventions: OTHER: Manual drainage & arm therapeutic exercise|OTHER: Cohesive bandaging & arm therapeutic exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assess Intraoperative Pain for Restorative Treatment of Maxillary 1st Permanent Molars Using Artinibsa Versus Artpharma in Children During Infiltration Technique
Status: UNKNOWN
Conditions: Pain
Interventions: OTHER: Artinibsa|OTHER: Artpharma
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of 2 Doses Versus 1 Dose of Acellular Pertussis Vaccines Containing Genetically-detoxified Pertussis Toxin in Young Adults Previously Primed With Acellular Pertussis Vaccines
Status: UNKNOWN
Conditions: Pertussis|Vaccine-Preventable Diseases
Interventions: DRUG: Pertagen®|DRUG: Revaxis®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Multicenter Study of Rasagiline in Parkinson's Disease Patients Using Levodopa and Experiencing Motor Fluctuations
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DRUG: rasagiline mesylate|DRUG: 1.0 mg rasagiline mesylate|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Efalizumab in the Treatment of Moderate-Severe Hydradenitis Suppurativa
Status: COMPLETED
Conditions: Hidradenitis Suppurativa
Interventions: DRUG: efalizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Upfront Autologous HSCT Versus Immunosuppression in Early Diffuse Cutaneous Systemic Sclerosis
Status: RECRUITING
Conditions: Systemic Sclerosis|Systemic Scleroses, Diffuse|Scleroderma|Scleroderma, Diffuse|Autologous Stem Cell Transplantation|Cyclophosphamide|Mycophenolate Mofetil|Treatment Strategy
Interventions: PROCEDURE: Upfront autologous HSCT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Food-effect Study of the Pediatric Dispersible Tablet Formulations of TRIUMEQ® and DOVATO® in Healthy Adult Participants
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: TRIUMEQ|DRUG: DOVATO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Management of Tarceva - Induced Rash in Patients With Non-Small Cell Lung Cancer.
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: Doxycline|DRUG: erlotinib [Tarceva]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Concurrent Subcutaneous Basal Insulin and Intravenous Insulin Pump in Hyperglycemic Crisis Patients Under Critical Care
Status: UNKNOWN
Conditions: Hyperglycaemic Crisis in Diabetes Mellitus|Diabetic Ketoacidosis|Hyperglycaemic Hyperosmolar Nonketotic Syndrome
Interventions: DRUG: Insulin Glargine 300 UNT/ML [Toujeo]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Remote Ischemic PreConditioning Effect on Postsurgical Pain
Status: COMPLETED
Conditions: Pain
Interventions: DEVICE: Thigh Tourniquet (VBM Single Use Tourniquet Cuff Items 20-34-722SLZ-1)|DEVICE: Sham RIPC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intravenous Sodium Fluorescein Versus Oral Phenazopyridine for Ureteral Patency
Status: WITHDRAWN
Conditions: Ureteral Injury
Interventions: DRUG: sodium fluorescein|DRUG: phenazopyridine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety of Use of Pandora for Patients Suffering From Gonarthrosis
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: DEVICE: Intra-articular single injection|DEVICE: Intra-articular three injections
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Feasibility Study for Real-time Remote CT Reading for Suspected Acute Appendicitis Using iPhone
Status: COMPLETED
Conditions: Telemedicine
Interventions: DEVICE: Remote CT reading using the iPhone|DEVICE: CT reading using LCD monitor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Idiopathic Pulmonary Fibrosis--Pathogenesis and Staging - SCOR in Occupational and Immunological Lung Diseases
Status: COMPLETED
Conditions: Lung Diseases|Pulmonary Fibrosis|Lung Diseases, Interstitial|Scleroderma, Systemic
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: ENavogliflozin DElivering Alleviation of Ventricular Diastolic Dysfunction in nonObstRuctive Hypertrophic CardioMyopathy
Status: RECRUITING
Conditions: Nonobstructive Hypertrophic Cardiomyopathy
Interventions: DRUG: enavogliflozin 0.3mg|DRUG: enavogliflozin Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Trial of Artesunate Combination Therapy in Pakistan
Status: COMPLETED
Conditions: Uncomplicated Falciparum Malaria
Interventions: DRUG: artesunate (AS)|DRUG: sulphadoxine-pyrimethamine (SP)|DRUG: Chloroquine (CQ)|DRUG: primaquine (PQ)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: DOTAREM®-Enhanced MRA Compared to GADOVIST®-Enhanced MRA in Patients With Abdominal or Lower Limb Arterial Diseases
Status: COMPLETED
Conditions: Peripheral Arterial Disease
Interventions: OTHER: Contrast-enhanced MRA - Imaging examination
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Exploratory Ph 2A, Double-Blind, Placebo-Controlled Dose Escalation Study of Safety, Tolerability, PD, & PK of HU6 for Subjects With Obese HFpEF
Status: COMPLETED
Conditions: Heart Failure With Preserved Ejection Fraction
Interventions: DRUG: HU6|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Myopia Control by Combining Auricular Acupoint and Atropine Eyedrops
Status: COMPLETED
Conditions: Myopia
Interventions: DRUG: 0.25 % atropine|DRUG: 0.5 % atropine|PROCEDURE: 0.25 % atropine+auricular acupoints
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Study of the Safety and Immune Response of Two Serogroup B Meningococcal Vaccines Administered to Healthy Adolescents
Status: COMPLETED
Conditions: Meningococcal Disease
Interventions: BIOLOGICAL: serogroup B meningococcal vaccine|BIOLOGICAL: serogroup B meningococcal vaccine|BIOLOGICAL: serogroup B meningococcal vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Neoadjuvant Study of DV in Combination Toripalimab or Sequence Chemotherapy in HR-negative, HER2 Low-expressing Breast Cancer
Status: RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Disitamab Vedotin Injection （18 weeks）|DRUG: Toripalimab （18weeks）|DRUG: Carboplatin|DRUG: Disitamab Vedotin Injection （12 weeks）|DRUG: Sequential Epirubicin|DRUG: Sequential CTX|DRUG: Toripalimab （12weeks）
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: I-gel vs. Endotracheal Intubation for Laparoscopic Gynaecological Procedures
Status: RECRUITING
Conditions: Intubation Complication|Laryngeal Mask Complication
Interventions: DEVICE: Supraglottic Airway Device|DEVICE: Endotracheal Tube
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Renal Nerves Stimulation Study
Status: COMPLETED
Conditions: Hypertension|Renal Denervation
Interventions: PROCEDURE: Electrical mapping, nerve stimulation checked renal denervation procedure|PROCEDURE: Electrial mapping, nerve stimulation guided renal denervation procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Influenza Vaccine During Sarcoidosis
Status: COMPLETED
Conditions: Sarcoidosis|Influenza Vaccine
Interventions: DRUG: Seasonal influenza vaccine available for the 2012-2013 vaccine campaign
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Telemedicine Strategy With Home Treatment Save Resources
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DEVICE: A videotelephone, TandBerg E20,|BEHAVIORAL: Behavioral motivation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Investigation of the Value of ctDNA in Diagnosis, Treatment, and Surveillance of Surgically Resectable Colorectal Cancer
Status: UNKNOWN
Conditions: Rectal Cancer, Adenocarcinoma|Neoadjuvant Chemoradiation
Interventions: DRUG: Capecitabine +/- Oxaliplatin|PROCEDURE: local resection|PROCEDURE: radical resection|OTHER: No adjuvant chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Carbon Dioxide, Oxygen and Mean Arterial Pressure After Cardiac Arrest and Resuscitation
Status: COMPLETED
Conditions: Out-of-Hospital Cardiac Arrest
Interventions: OTHER: Low normal PaCO2|OTHER: High normal PaCO2|OTHER: Low normal PaO2|OTHER: High normal PaO2|OTHER: Low normal MAP|OTHER: High normal MAP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Etoricoxib in Acute Soft Tissue Rheumatism Affecting the Shoulder
Status: TERMINATED
Conditions: Soft Tissue Injuries of the Shoulder|Tenosynovitis and Bursitis Affecting the Shoulder
Interventions: DRUG: Etoricoxib 60 mg|DRUG: Etoricoxib 90 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study Comparing the Effects of Latanoprostene Bunod and Timolol on Retinal Blood Vessel Density and Visual Acuity
Status: COMPLETED
Conditions: OAG - Open-Angle Glaucoma|OHT - Ocular Hypertension
Interventions: DRUG: Latanoprostene bunod 0.024% QD|DRUG: Timolol maleate 0.5% BID
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Citicoline and Omega-3 Fatty Acid Effects in Veterans With Traumatic Brain Injury (TBI)
Status: WITHDRAWN
Conditions: Traumatic Brain Injury|Substance Abuse|Substance Dependence
Interventions: DRUG: Citicoline|DRUG: Omega-3|OTHER: Rice bran oil|OTHER: Microcrystalline Cellulose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of ProQuad™ in Healthy Children in Korea (V221-023)
Status: TERMINATED
Conditions: Measles|Mumps|Rubella|Varicella
Interventions: BIOLOGICAL: Measles, Mumps, Rubella and Varicella (Oka-Merck) Virus Vaccine Live (ProQuad™)|BIOLOGICAL: M-M-R™ II and Varivax™
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Pre-biotics and Probiotics for Constipation in Parkinson's Disease
Status: COMPLETED
Conditions: Constipation
Interventions: OTHER: Probiotics and prebiotic|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial of Interventions to Support Family Surrogates of Critically Ill Patients
Status: RECRUITING
Conditions: Grief|Trauma|Psychotherapy|Critical Care
Interventions: BEHAVIORAL: EMPOWER|OTHER: Supportive Conversation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PHAGE Study: Bacteriophages as Novel Prebiotics
Status: COMPLETED
Conditions: Gastrointestinal Disorder, Functional
Interventions: DIETARY_SUPPLEMENT: Bacteriophage mixture|OTHER: Placebo Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Relationships Between the Use of Antimalarial Drugs in Pregnancy and Plasmodium Falciparum Resistance
Status: COMPLETED
Conditions: Malaria in Pregnancy|Birth Weight|Anaemia
Interventions: DRUG: sulphadoxine-pyrimethamine|DRUG: chloroquine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy in Treating Children With Newly Diagnosed Acute Myeloid Leukemia or Myelodysplastic Syndrome
Status: COMPLETED
Conditions: Leukemia|Myelodysplastic Syndromes
Interventions: DRUG: cytarabine|DRUG: daunorubicin hydrochloride|DRUG: dexamethasone|DRUG: etoposide|DRUG: idarubicin|DRUG: mitoxantrone hydrochloride|DRUG: thioguanine|PROCEDURE: allogeneic bone marrow transplantation|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: The Incidence of Adjacent Synchronous Ipsilateral Infiltrating Carcinoma and/or DCIS in Patients Diagnosed With Intraductal Papilloma Without Atypia or Flat Epithelial Atypia by Core Needle Biopsy
Status: ACTIVE_NOT_RECRUITING
Conditions: Flat Epithelia Atypia|Intraductal Papilloma Without Atypia
Interventions: OTHER: Pathologic evaluation of excised tissue
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Randomized Controlled Clinical Trial Of Oral Health-Related Quality Of Life In Patients Wearing Vacuum Formed Thermoplastic Retainers Constructed On Conventional Stone Models And On 3D Reconstructed Orthodontic Study Model
Status: COMPLETED
Conditions: Quality of Life
Interventions: DEVICE: Vacuum Formed Thermoplastic Retainers Constructed On 3D Reconstructed Orthodontic Study Model
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Animal-Assisted Visitation Program Chlorhexidine Trial
Status: RECRUITING
Conditions: Methicillin-resistant Staphylococcus Aureus|Clostridium Difficile|Pseudomonas Aeruginosa
Interventions: DRUG: Chlorhexidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: F-URS and Mini PCNL for Pediatric Urolithiasis
Status: NOT_YET_RECRUITING
Conditions: Urolithiasis
Interventions: PROCEDURE: Mini PCNL (mini percutaneous nephrolithotomy)|PROCEDURE: RIRS (retrograde intrarenal surgery/ flexible URS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Prehabilitation Program for Frail Patients Undergoing Cardiac Surgeries/Procedures
Status: RECRUITING
Conditions: Coronary Artery Bypass Grafting|Heart Valve Replacement|Transcatheter Aortic Valve Implantation|Frailty
Interventions: BEHAVIORAL: Multi-component exercise programme|OTHER: Attention Placebo|BEHAVIORAL: Structured preoperative education|BEHAVIORAL: Nutritional optimization|BEHAVIORAL: Stress management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Posterior Cervical Stabilization System (PCSS) as Part of Circumferential Fusion to Treat Multilevel DDD
Status: ACTIVE_NOT_RECRUITING
Conditions: Degenerative Disc Disease
Interventions: PROCEDURE: Anterior Cervical Discectomy and Fusion|DEVICE: Posterior Cervical Stabilization System (PCSS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study of the Monoclonal Antibody IMT-009 in Patients With Advanced Solid Tumors or Lymphomas
Status: RECRUITING
Conditions: Non Small Cell Lung Cancer|Head and Neck Squamous Cell Carcinoma|Triple Negative Breast Cancer|Cutaneous Squamous Cell Carcinoma|Hormone Receptor Positive Breast Carcinoma|Small Bowel Cancer|Esophageal Cancer|Colorectal Cancer|Diffuse Large B Cell Lymphoma|Hodgkin Lymphoma|Burkitt Lymphoma|Follicular Lymphoma
Interventions: DRUG: IMT-009|COMBINATION_PRODUCT: Fruquintinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Short-Term vs. Long-Term Valganciclovir Therapy for Symptomatic Congenital CMV Infections
Status: COMPLETED
Conditions: Cytomegalovirus Infection
Interventions: OTHER: Placebo|DRUG: Valganciclovir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Sequential Therapy as Second Line Therapy for Refractory Helicobacter Pylori Infection - A Pilot Study
Status: COMPLETED
Conditions: H. Pylori Infection
Interventions: DRUG: Cravit-based sequential therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Advair HFA For Chronic Obstructive Pulmonary Disease(COPD)
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Fluticasone Propionate/Salmeterol DISKUS 250/50mcg|DRUG: Fluticasone Propionate/Salmeterol Hydrofluoroalkane 134a MDI 230/42mcg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating Comparative Effectiveness of Empagliflozin in Type 2 Diabetes Population With and Without Chronic Kidney Disease
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Empagliflozin|DRUG: Dipeptidyl Peptidate-4 inhibitors|DRUG: Sodium glucose co-transporter-2 inhibitors|DRUG: Glucagon-like Peptide-1 Receptor Agonists
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Deferasirox Relative to Subcutaneous Deferoxamine in Sickle Cell Disease Patients
Status: COMPLETED
Conditions: Sickle Cell Disease|Iron Overload|Hemolytic Anemia
Interventions: DRUG: Deferasirox (ICL670)|DRUG: Deferoxamine (DFO)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Assessment of HAV in Patients Needing Vascular Access for Dialysis
Status: COMPLETED
Conditions: Renal Failure|End Stage Renal Disease|Vascular Access|Hemodialysis
Interventions: BIOLOGICAL: HAV
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pediatric Second Influenza Dose Portal Reminder Recall
Status: COMPLETED
Conditions: Influenza|Respiratory Tract Infections
Interventions: BEHAVIORAL: Portal Reminders for Second Dose of Influenza Vaccine with Direct Scheduling Link|BEHAVIORAL: Portal Reminders for Second Dose of Influenza Vaccine without Direct Scheduling Link
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Efficacy of the Use of Silver Diamine Fluoride and Sodium Fluoride Varnish for the Treatment of Caries in Children
Status: COMPLETED
Conditions: Dental Caries in Children
Interventions: COMBINATION_PRODUCT: Silver diamine fluoride 38% followed by Sodium fluoride varnish 5%
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Osteopathic Manipulative Treatment in People With Neurogenic Bowel Dysfunction
Status: UNKNOWN
Conditions: Central Nervous System Injury|Neurogenic Bowel Dysfunction
Interventions: OTHER: Osteopathic Manipulative Treatment|OTHER: Nursing Educational Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasonically Activated Scalpel Versus Electrocautery Based Dissection in Acute Cholecystitis Trial
Status: COMPLETED
Conditions: Cholecystitis, Acute
Interventions: PROCEDURE: Ultrasonically activated scalpel|PROCEDURE: Electrocautery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 5 Day Concomitant Versus 10 Day Sequential Therapy for Eradication of H. Pylori Infection
Status: COMPLETED
Conditions: Helicobacter Pylori Infection
Interventions: DRUG: Eradication therapy (amoxicillin; esomeprazole; tinidazole; levofloxacin)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Curcumin in Patients in Chronic Kidney Disease
Status: COMPLETED
Conditions: Chronic Kidney Diseases
Interventions: DIETARY_SUPPLEMENT: Active Comparator: Supplement A|DIETARY_SUPPLEMENT: Placebo Comparator: Supplement B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Phase IV Trial to Collect Safety Data and Sera in Healthy Children Given Fluzone Vaccine
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Influenza Virus Vaccine (Fluzone®)|BIOLOGICAL: Influenza Virus Vaccine (Fluzone®)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Stress Management for High Blood Pressure
Status: UNKNOWN
Conditions: Prehypertension
Interventions: BEHAVIORAL: Mindfulness-Based Stress Reduction|BEHAVIORAL: Stress Management Education|OTHER: American Heart Association Recommended Self-Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Clopidogrel Proton-Pump Inhibitors Study
Status: WITHDRAWN
Conditions: Coronary Artery Disease
Interventions: DRUG: Omeprazole|DRUG: Pantoprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Levonorgestrel Intrauterine System, Copper T Intrauterine Device and Oral Contraceptives on Life Quality
Status: WITHDRAWN
Conditions: Contraceptive Methods Comparison
Interventions: DRUG: YASMIN® (Drospirenone/Ethinyl Estradiol)|DEVICE: The Copper-T is an intrauterine device (IUD)|DEVICE: levonorgestrel-releasing system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Controlled Trial of High-risk Coronary Intervention With Percutaneous Left Ventricular Unloading
Status: RECRUITING
Conditions: Ischemic Heart Disease|Coronary Artery Disease
Interventions: DEVICE: Percutaneous left ventricular unloading
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of POMx Capsules in Men With Recurrent Prostate Cancer: An 18-Month Study
Status: COMPLETED
Conditions: Recurrent Prostate Cancer
Interventions: DRUG: 3 POMx capsules|DRUG: 1 POMx capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multicenter Study Using IMC to Analyze the Impact of ICANS on Microglia
Status: COMPLETED
Conditions: ICANS, Grade Unspecified|CAR T-Cell-Related Encephalopathy Syndrome
Interventions: DIAGNOSTIC_TEST: There will be no intervention as we will study patients that undergo autopsy after CAR T cell infusion.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Application of Indocyanine Green Labeled Fluorescent Laparoscopy in Proximal Gastric Cancer
Status: NOT_YET_RECRUITING
Conditions: Gastric Cancer
Interventions: BEHAVIORAL: indocyanine green labeled fluorescent laparoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Study of a New Catheter Using Force Sensing Capabilities for the Treatment of Atrial Fibrillation and Ventricular Tachycardia
Status: COMPLETED
Conditions: Atrial Fibrillation|Ischemic Ventricular Tachycardia
Interventions: DEVICE: Radiofrequency Catheter Ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PeRioperative Immunotherapy Combined With Sacituzumab Govitecan in Muscle Invasive blAdder Cancer
Status: NOT_YET_RECRUITING
Conditions: Urothelial Bladder Carcinoma
Interventions: DRUG: Sacituzumab govitecan|DRUG: Zimberelimab|DRUG: Domvanalimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Daratumumab, Ixazomib, and Dexamethasone in AL Amyloidosis
Status: ACTIVE_NOT_RECRUITING
Conditions: Newly Diagnosed Primary Amyloidosis|Recurrent Primary Amyloidosis|Refractory Primary Amyloidosis
Interventions: BIOLOGICAL: Daratumumab|DRUG: Dexamethasone|DRUG: Ixazomib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of N2O on Chronic Neuropathic Pain Patients
Status: UNKNOWN
Conditions: Neuropathic Pain
Interventions: DRUG: N2O|DRUG: Oxygen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT