pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Consolidative Radiotherapy (CSRT) in Patients With Oligometastatic/Locally Advanced Unresectable Bilary Tract Cancer (BTC)
Status: NOT_YET_RECRUITING
Conditions: Biliary Tract Cancer
Interventions: RADIATION: Consolidative radiotherapy|DRUG: Standard-of-care systemic therapy: Gemcitabine + cisplatin/oxaliplatin + Durvalumab/Pembrolizumab/Sintilimab/Toripalimab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of CD40L-Augmented TIL for Patients With EGFR, ALK, ROS1 or HER2-Driven NSCLC
Status: RECRUITING
Conditions: Non Small Cell Lung Cancer|Stage IV Non-small Cell Lung Cancer|Recurrent Non Small Cell Lung Cancer
Interventions: BIOLOGICAL: Tumor-infiltrating Lymphocytes (TIL)|DRUG: Nivolumab|DRUG: Cyclophosphamide|DRUG: Fludarabine|OTHER: Tumor-infiltrating Lymphocyte Therapy|DRUG: Interleukin-2 (IL2)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunosurveillance for Metastatic Colorectal Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Monitoring, Immunologic
Interventions: DIETARY_SUPPLEMENT: Adenorine|BIOLOGICAL: Placebo|DRUG: FOLFOX regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Consumption of Dairy Product on Upper Gastric Discomfort
Status: COMPLETED
Conditions: Upper Gastric Discomfort
Interventions: OTHER: 1- Test dairy product containing specific ingredients|OTHER: 2- Control dairy product without specific ingredients
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pilot Study: Sectio Bonding/Early Skin-to-skin Contact (SSC) After Caesarean Section
Status: COMPLETED
Conditions: Early Skin-to-skin Contact
Interventions: PROCEDURE: early SSC|PROCEDURE: late SSC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study to Evaluate Handling Errors in Usage of SERETIDE® Metered Dose Inhaler (MDI) (EVOHALER®) by Adult Subjects Currently Using the SERETIDE DISKUS® Inhaler
Status: COMPLETED
Conditions: Asthma
Interventions: DEVICE: SERETIDE MDI|DEVICE: Placebo DISKUS Inhaler|DEVICE: Placebo MDI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Cap-assisted Chromoendoscopy as a Screening Test for Colorectal Neoplasm Using Web-based Research Network
Status: COMPLETED
Conditions: Colorectal Neoplasm
Interventions: DEVICE: cap-assisted chromoendoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Long-Term Follow-up Study for Multiple Myeloma Patients Who Received Study Treatment (Plerixafor or Placebo) in the AMD3100-3102 Study (NCT00103662).
Status: COMPLETED
Conditions: Multiple Myeloma|Autologous Transplantation
Interventions: DRUG: Placebo|DRUG: plerixafor|DRUG: granulocyte colony-stimulating factor (G-CSF)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Two Regimens of Liposomal Doxorubicin in Treating Women With Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: pegylated liposomal doxorubicin hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Randomized MMF Withdrawal in Systemic Lupus Erythematosus (SLE)
Status: TERMINATED
Conditions: Systemic Lupus Erythematosus|SLE
Interventions: DRUG: Mycophenolate Mofetil|DRUG: Hydroxychloroquine or Chloroquine|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: iDropper Usability in Glaucoma
Status: WITHDRAWN
Conditions: Glaucoma, Open-Angle [C11.525.381.407]
Interventions: DEVICE: Open angle glaucoma - iDropper device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Ofatumumab (Humax-CD20) With CHOP (Cyclophosphamide,Doxorubicin, Vincristine, Predisolone) in Follicular Lymphoma (FL) Patients
Status: COMPLETED
Conditions: Lymphoma, Follicular
Interventions: DRUG: Ofatumumab|DRUG: Cyclophosphamide|DRUG: Doxorubicin|DRUG: Vincristine|DRUG: Prednisolone, Prednisone or equivalent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tapinarof for the Treatment of Plaque Psoriasis in Adults (3002)
Status: COMPLETED
Conditions: Plaque Psoriasis
Interventions: DRUG: Tapinarof|DRUG: Vehicle Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: REGN7257 in Adult Patients With Severe Aplastic Anemia That Is Refractory to or Relapsed on Immunosuppressive Therapy
Status: RECRUITING
Conditions: Severe Aplastic Anemia (SAA)
Interventions: DRUG: REGN7257
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cyclophosphamide in Treating Young Patients With Severe Autoimmune Enteropathy
Status: COMPLETED
Conditions: Diarrhea|Gastrointestinal Complications|Unspecified Childhood Solid Tumor, Protocol Specific
Interventions: BIOLOGICAL: filgrastim|DRUG: cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of Mirikizumab in Healthy Chinese Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Mirikizumab - IV|DRUG: Mirikizumab - SC|DRUG: Placebo - IV|DRUG: Placebo - SC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Neoadjuvant Therapy of Camrelizumab Combined With Chemotherapy for Resectable Locally Advanced Esophageal Squamous Cell Carcinoma
Status: RECRUITING
Conditions: Esophageal Carcinoma
Interventions: DRUG: camrelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Effectiveness of Uterine Repair Surgery on Preventing Recurrence of Cesarean Sar Pregnancy
Status: COMPLETED
Conditions: Pregnancy Complications
Interventions: PROCEDURE: Active comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intubation of Morbidly Obese Patients. A Clinical Trial, Comparing Glide Scope ® With Fastrach TM
Status: COMPLETED
Conditions: Morbidly Obese|Intubationtime|Intubationattempts
Interventions: DEVICE: GlideScope|DEVICE: Fastrach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Sugammadex Versus Neostigmine in Patients With Liver Cirrhosis Undergoing Liver Resection
Status: COMPLETED
Conditions: Cirrhosis and Chronic Liver Disease
Interventions: DRUG: Sugammadex|DRUG: Neostigmine|DRUG: Rocuronium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single Dose Bioequivalence Study of Darifenacin Tablets 7.5 mg in Fed Healthy Volunteers.
Status: UNKNOWN
Conditions: Bioequivalency
Interventions: DRUG: Darifenacin|DRUG: Darifenacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Care of Older People With Cognitive Impairment or Dementia Hospitalized in Traumatology Units
Status: UNKNOWN
Conditions: Dementia|Femur Fracture|Continuity of Patient Care
Interventions: BEHAVIORAL: CARExDEM
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: SUMMIT Study: A Study of Persistence to Bonviva (Ibandronate) Once Monthly in Women With Post-Menopausal Osteoporosis.
Status: COMPLETED
Conditions: Post Menopausal Osteoporosis
Interventions: DRUG: ibandronate [Bonviva/Boniva]|DRUG: ibandronate [Bonviva/Boniva]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Trial to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of SHR-3167 Single Injection in Healthy Subjects and Patients With Type 2 Diabetes
Status: RECRUITING
Conditions: T2DM
Interventions: DRUG: SHR-3167|DRUG: SHR-3167 Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study in Allergic Rhinitis Patients After Intranasal Administration of AZD8848
Status: COMPLETED
Conditions: Allergic Rhinitis
Interventions: DRUG: AZD8848|DRUG: Placebo|DRUG: AZD8848 and placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bryostatin + Fludarabine in Treating Patients With Chronic Lymphocytic Leukemia or Relapsed Indolent Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Leukemia|Lymphoma
Interventions: DRUG: bryostatin 1|DRUG: fludarabine phosphate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of Resistance Training on Glycemic Control for Patients With Type 2 Diabetes in Cardiac Rehabilitation
Status: COMPLETED
Conditions: Type 2 Diabetes (T2DM)|Cardiovascular Disease
Interventions: OTHER: Resistance Training|OTHER: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Distribution Circumferential Versus Non Circumferential of Mepivacaine in the Median and Ulnar Nerves
Status: COMPLETED
Conditions: Anesthesia
Interventions: PROCEDURE: Circumferential spread of the mepivacaine ultrasonographic guided around the median and ulnar nerves at the elbow|PROCEDURE: Non circumferential spread in ultrasound-guided median and ulnar nerves block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Meal Timing on Glycemic Profiles in Adolescents With Type 2 Diabetes
Status: RECRUITING
Conditions: Pediatric Obesity|Type 2 Diabetes|Time Restricted Eating
Interventions: BEHAVIORAL: Time Limited Eating|BEHAVIORAL: Components Common to All Study Arms.|BEHAVIORAL: Control|DEVICE: Continuous Glucose Monitor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 in Patients With HLA-A*0201+ and WT1+ Recurrent/Metastatic Cancers
Status: ACTIVE_NOT_RECRUITING
Conditions: Colorectal Cancer|Gastric Cancer|Pancreatic Cancer|Ovarian Cancer
Interventions: DRUG: CUE-102
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Caffeine on Time to Anesthetic Emergence After Laparoscopic Cholecystectomy : Randomized-controlled Trial
Status: UNKNOWN
Conditions: Laparoscopic Cholecystectomy
Interventions: DRUG: 300 mg of caffeine citrate infusion|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Telmisartan on Ischemic Cardiovascular Events in High-risk Hypertensive Patients
Status: TERMINATED
Conditions: Acute Myocardial Infarction|Angina Pectoris|Myocardial Ischemia|Acute Coronary Syndrome|Hypertension
Interventions: DRUG: Micardis (Telmisartan)|DRUG: Blopress (Candesartan)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Hybrid APC for Gastric Low Grade Intraepithelial Neoplasia
Status: RECRUITING
Conditions: Gastric Low Grade Intraepithelial Neoplasia
Interventions: PROCEDURE: Hybrid Argon Plasma Coagulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PRescribing INterventions for Chronic Pain Via the Electronic Health Record Study - Current Opioid-User Population
Status: COMPLETED
Conditions: Opioid-use Disorder|Opioid Use|Opioid Abuse
Interventions: BEHAVIORAL: Choice Architecture Nudge|BEHAVIORAL: PMP Integration & Nudge
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Imatinib in Patients With Intermediate-risk Gastrointestinal Stromal Tumor With a High-risk Genomic Grade Index
Status: UNKNOWN
Conditions: Gastrointestinal Stromal Tumor
Interventions: DRUG: Imatinib|OTHER: Surveillance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Heart Failure Insomnia Treatment Study
Status: COMPLETED
Conditions: Heart Failure|Cardiac Failure|Congestive Heart Failure|Insomnia|Sleep Disorder|Sleep Initiation and Maintenance Disorders|Disorders of Initiating and Maintaining Sleep|Anxiety|Depression
Interventions: BEHAVIORAL: Brief treatment for Insomnia|BEHAVIORAL: Sleep Monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Smartphone Applications to Improve Lifestyles in Olders Over 65 Years
Status: COMPLETED
Conditions: Telemedicine
Interventions: BEHAVIORAL: Intervention (training in use of a Smartphone application)|BEHAVIORAL: Control (Advice on healthy diet and physical activity recommendations)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety Study of Farletuzumab, Carboplatin and Pegylated Liposomal Doxorubicin (PLD) to Treat Platinum-sensitive Ovarian Cancer
Status: COMPLETED
Conditions: Epithelial Ovarian Cancer
Interventions: DRUG: Farletuzumab, Carboplatin, and PLD
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Balance and Motion Coordination Parameters Can be Improved in Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Gait Disorders, Neurologic
Interventions: PROCEDURE: Balance training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Benefits of R Anastomotic Technique for Billroth-II Reconstruction With Braun Anastomosis During Totally Laparoscopic Distal Gastrectomy: a Propensity Score Matching Analysis
Status: COMPLETED
Conditions: the Incidences of Clavien-Dindo Grade II or Higher|Anastomotic Time
Interventions: PROCEDURE: R anastomosis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Dose-dense Doxorubicin/Cyclophosphamide With Intermittent Low-dose Sunitinib in Breast Cancer Patients
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: DRUG: Dose-dense doxorubicin/cyclophosphamide + sunitinib|DRUG: Dose-dense doxorubicin/cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Refractive Treatment of Early Keratoconus
Status: UNKNOWN
Conditions: Keratoconus
Interventions: PROCEDURE: Crosslinking|PROCEDURE: Photorefractive keratectomy|DEVICE: iDesign® Advanced WaveScan Studio
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Imaging of Prostate and Breast Cancer Bone Metastases Using Magnetic Resonance Imaging and Nuclear Medicine Techniques
Status: COMPLETED
Conditions: Bone Metastases
Interventions: RADIATION: BS, SPECT/CT, PET/CT, MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Introduction of a Novel PAOO Technique
Status: ACTIVE_NOT_RECRUITING
Conditions: Bone Loss|Tooth Movement
Interventions: PROCEDURE: Bone augmentation with minimally invasive corticotomy (piezotomy)|PROCEDURE: Bone augmentation without corticotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect to the Photobiomodulation in the Burning Mouth Syndrome
Status: COMPLETED
Conditions: Burning Mouth Syndrome|Quality of Life|Anxiety Depression|Dry Mouth
Interventions: RADIATION: Low frequency laser activated photobiomodulation|OTHER: Low frequency laser photobiomodulation inactive
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Preventing Young Infant Infections Using Azithromycin in Labour (PreYIAL) Trial
Status: COMPLETED
Conditions: Bacterial Infections
Interventions: DRUG: Azithromycin 500 mg Oral Tablet x 4|DRUG: Matching Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: TACE Combined With Anti-PD-1 Antibody in Patients With Advanced Hepatocellular Carcinoma
Status: RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Sintilimab|COMBINATION_PRODUCT: TACE
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The FLiP Study, a Pilot Cluster Randomized Trial
Status: UNKNOWN
Conditions: Femur Fracture
Interventions: PROCEDURE: Antegrade femoral nailing Supine Position|PROCEDURE: Antegrade Femoral Nailing Lateral Position
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Virtual Reality Rehabilitation to Promote Motor Recovery in Amputees
Status: NOT_YET_RECRUITING
Conditions: Lower Limb Amputation Knee|Injuries|Biomechanical Lesion
Interventions: BEHAVIORAL: Virtual environment practiced on the Caren|BEHAVIORAL: Conventional physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Standardization of Non-academic Center Surgical Morbidity and Mortality Conference: a Type I Hybrid Implementation Non-clinical Trial.
Status: TERMINATED
Conditions: Surgery|Surgery--Complications
Interventions: BEHAVIORAL: Morbidity and mortality conference toolkit
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Bioavailability Study of Doxycycline Monohydrate Capsules and Monodox Under Fasting Conditions
Status: COMPLETED
Conditions: To Determine Bioequivalence Under Fasting Conditions
Interventions: DRUG: Doxycycline Monohydrate|DRUG: Monodox
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Breast Capsular Contracture Following Post-Mastectomy Reconstruction in Women Treated With the Leukotriene Inhibitor Zafirlukast: A Phase II Trial
Status: TERMINATED
Conditions: Breast Cancer
Interventions: DRUG: zafirlukast|OTHER: Standard of Care (no intervention)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of a New Topical Formulation With Imiquimod (Limtop) Applied 1, 3 or 7 Times Weekly During 2 x 2 Weeks Treatment for Actinic Keratosis on the Head
Status: COMPLETED
Conditions: Actinic Keratosis
Interventions: DRUG: Imiquimod (topical use)
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose:
Clinical trial: Comparison of Ultrasound-guided Steroid Injection and Dry Needling in Piriformis Muscle Syndrome
Status: NOT_YET_RECRUITING
Conditions: Piriformis Muscle Syndrome
Interventions: OTHER: corticosteroid injection|OTHER: dry needling|OTHER: exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of iMmune Function in Post-surgical and AuToimmune HYpoparathyroidism (EMPATHY)
Status: COMPLETED
Conditions: Hypoparathyroidism|Hypoparathyroidism Postprocedural|Hypoparathyroidism Due to Impaired Parathormone Secretion
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pectoral Nerve Blocks (PECs) for Cardiovascular Implantable Electronic Device Placement
Status: ACTIVE_NOT_RECRUITING
Conditions: Pain, Postoperative|Pain, Acute|Pain, Chest|Pain|Satisfaction, Patient|Opioid Use, Unspecified|Opioids; Harmful Use
Interventions: DRUG: 0.25% Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Trial to Study the Safety and Efficacy of SM-020 Gel 1.0% in Subjects With Dermatosis Papulosa Nigra (DPN)
Status: ACTIVE_NOT_RECRUITING
Conditions: Dermatosis Papulosa Nigra
Interventions: DRUG: SM-020 gel 1.0%
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SUPerficial ENDometriosis In Magnetic Resonance Imaging
Status: NOT_YET_RECRUITING
Conditions: Endometriosis
Interventions: RADIATION: Magnetic resonance imaging, 3DT1 sequence|PROCEDURE: Laparoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Human Umbilical Cord-Derived Mesenchymal Stem Cells(BC-U001) for Rheumatoid Arthritis
Status: UNKNOWN
Conditions: Rheumatoid Arthritis
Interventions: DRUG: hUC-MSC infusion (BC-U001)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mediolateral Episiotomy and Obstetric Anal Sphincter Injuries in Instrumental Delivery
Status: UNKNOWN
Conditions: Obstetric Anal Sphincter Injury|Episiotomy Wound|Anal Incontinence|Pelvic Floor Disorders|Depression
Interventions: PROCEDURE: Mediolateral episiotomy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Subcutaneous Golimumab in Chinese Patients With Active Rheumatoid Arthritis Despite Methotrexate Therapy
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Golimumab|DRUG: Placebo|DRUG: Methotrexate (MTX)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sickle Cell Disease and CardiovAscular Risk - Red Cell Exchange Trial (SCD-CARRE)
Status: RECRUITING
Conditions: Sickle Cell Disease
Interventions: BIOLOGICAL: Red Blood Cell|OTHER: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Endurance Training on Body Composition and Insulin Sensitivity in Prostate Cancer Patients Receiving Androgen Deprivation Therapy
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: BEHAVIORAL: Endurance training
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: NIMH K23: Modulation of Frontoparietal Dynamics in Adolescent Working Memory Deficits
Status: RECRUITING
Conditions: Working Memory
Interventions: DEVICE: Active Intermittent Theta Burst Stimulation|DEVICE: Sham Intermittent Theta Burst Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Safety of Bilateral Theta Burst Stimulation for the Treatment of Auditory Hallucinations
Status: COMPLETED
Conditions: Auditory Hallucinations
Interventions: PROCEDURE: continuous theta burst stimulation (cTBS)|PROCEDURE: sham cTBS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rifabutin Therapy for the Prevention of Mycobacterium Avium Complex (MAC) Bacteremia in HIV Positive Patients With CD4 Counts = or < 200: Treatment IND Study
Status: COMPLETED
Conditions: Mycobacterium Avium-intracellulare Infection|HIV Infections
Interventions: DRUG: Rifabutin
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: The Effect Of Antenatal Corticosteroids On Early And Late Perinatal Outcomes
Status: COMPLETED
Conditions: Preterm Pregnancy|Antenatal Corticosteroid|Perinatal Problems
Interventions: OTHER: participants receiving Corticosteroid
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: SARS Cov_2 Incidence of Healthy Health Workers
Status: COMPLETED
Conditions: SARS COV-2 IgG Levels on Health Workers
Interventions: DIAGNOSTIC_TEST: Spike protein (S) or the nucleocapsid (N) of SARS-CoV-2
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Progression Delaying Effect of Escitalopram in Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: escitalopram|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Upper Extremity Robotic Rehabilitation in Patients With Hemiplegia
Status: COMPLETED
Conditions: Hemiplegia and/or Hemiparesis Following Stroke
Interventions: OTHER: Robotic therapy|OTHER: Conventional therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Switching to a Fixed Dose Combination of Bictegravir/Emtricitabine/Tenofovir Alafenamide (B/F/TAF) in Human Immunodeficiency Virus Type 1 (HIV-1) Infected Adults Who Are Virologically Suppressed
Status: COMPLETED
Conditions: HIV-1-infection
Interventions: DRUG: B/F/TAF|DRUG: F/TAF|DRUG: DTG|DRUG: DTG Placebo|DRUG: F/TAF Placebo|DRUG: B/F/TAF Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Baclofen to Reduce Alcohol Use in Veterans With HCV
Status: COMPLETED
Conditions: Hepatitis C|Alcohol Use Disorders
Interventions: DRUG: baclofen|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of GS010 for Treatment of Vision Loss From 7 Months to 1 Year From Onset in LHON Due to the ND4 Mutation (REVERSE)
Status: COMPLETED
Conditions: Optic, Atrophy, Hereditary, Leber
Interventions: BIOLOGICAL: GS010|DEVICE: Sham Intravitreal Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Blended Care for the Discontinuation of Benzodiazepine Use
Status: COMPLETED
Conditions: Benzodiazepine Dependence|Benzodiazepine Dependent|Benzodiazepine Withdrawal
Interventions: BEHAVIORAL: Blended care|BEHAVIORAL: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Laser Therapy for At-Home Treatment of Diabetic Foot Ulcers - Canada
Status: UNKNOWN
Conditions: Diabetic Foot Ulcer
Interventions: DEVICE: B-Cure Laser Pro|DEVICE: Sham laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Cipralex on Quality of Life, Adrenal Activity Glucose Metabolism, Physical and Mental Health in PCOS
Status: COMPLETED
Conditions: Polycystic Ovary Syndrome
Interventions: DRUG: Cipralex|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Recalcitrant Hand and Foot Warts With Intense Pulsed Light - a Randomized Controlled Trial
Status: UNKNOWN
Conditions: Warts
Interventions: PROCEDURE: Intense Pulsed Light + paring versus paring alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose:
Clinical trial: Evaluation of a Local Preconditioning Effect in Patients Undergoing Cardiac Surgery
Status: TERMINATED
Conditions: Heart Disease|Coronary Artery Bypass Graft Triple Vessel
Interventions: DEVICE: PICSO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of ART4215 for the Treatment of Advanced or Metastatic Solid Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Cancer|Metastatic Cancer|Breast Cancer
Interventions: DRUG: ART4215|DRUG: Talazoparib|DRUG: Niraparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lyrica (Pregabalin) Korean Post Marketing Surveillance Study
Status: COMPLETED
Conditions: Epilepsy|Neuropathic Pain|Fibromyalgia|Post-market Surveillance
Interventions: DRUG: pregabalin (Lyrica)|DRUG: pregabalin (Lyrica)|DRUG: pregabalin (Lyrica)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Nimotuzumab in EGFR Highly Expressed Pancreatic Neuroendocrine Neoplasms
Status: NOT_YET_RECRUITING
Conditions: Pancreatic Neuroendocrine Neoplasm
Interventions: DRUG: Nimotuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Biological Samples Obtained by Leukapheresis Induced by Two BCG Vaccinations in BCG-naïve Healthy Adults in the US
Status: COMPLETED
Conditions: Tuberculosis
Interventions: BIOLOGICAL: bacillus Calmette-Guérin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Botulinum Neurotoxin Type A (BoNT/A) Free of Complexing Proteins in the Spastic Equinovarus Foot
Status: COMPLETED
Conditions: Stroke Rehabilitation|Stroke Rehabilitation Spasticity Management
Interventions: DRUG: IncobotulinumtoxinA|DRUG: OnabotulinumtoxinA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acute and Short-term Chronic Effects of Galvus (Vildagliptin) in Diabetes Type 2 Obese Women
Status: COMPLETED
Conditions: 1- Microvascular Function|2-oxidative Stress|3-inflammation
Interventions: DRUG: Vildagliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Exploring Physical and Psychological Needs and Quality of Life in Patients With Advanced Cancer Receiving Immunotherapy
Status: RECRUITING
Conditions: Cancer|Immunotherapy|IrAE|Distress, Emotional|Care Need|Financial Toxicity|Quality of Life
Interventions: OTHER: Line-based questionnaire follow-up
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Effect of Lactobacillus Rhamnosus on Serum Uremic Toxins in Hemodialysis
Status: COMPLETED
Conditions: Hemodialysis Complication
Interventions: DIETARY_SUPPLEMENT: Lactobacillus rhamnosus|DRUG: Placebo - Cap
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Phone Calls Intervention on Diabetic Patients After Ambulatory Discharge of a Tertiary Care Center
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: OTHER: Primary Care|OTHER: Phone Calls Support and Primary Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study of Sativex® for Relief of Peripheral Neuropathic Pain Associated With Allodynia.
Status: COMPLETED
Conditions: Pain|Peripheral Neuropathy
Interventions: DRUG: Sativex®|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Efficacy and Safety of Utidelone Plus Tirelizumab and Bevacizumab for Advanced or Metastatic Triple-negative Breast Cancer (UTILIZABLE) ：Single-arm, Prospective, Open Clinical Study
Status: RECRUITING
Conditions: TNBC - Triple-Negative Breast Cancer
Interventions: DRUG: Utidelone|DRUG: Tirelizumab|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of The Substitution of Animal Protein by Soya-Based Fermented Product on Human Gut Microbiome
Status: NOT_YET_RECRUITING
Conditions: Gut Microbiome
Interventions: DIETARY_SUPPLEMENT: 100g fermented Tofu
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Targeting Reactive Oxygen Species Production as a Novel Therapeutic in Fuch's Endothelial Corneal Dystrophy
Status: RECRUITING
Conditions: Fuchs Endothelial Corneal Dystrophy
Interventions: DRUG: N-acetyl cysteine (NAC) 10% solution|DRUG: N-acetyl cysteine (NAC) 20% solution|DRUG: Visine Dry Eye Relief eye drops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Local Wound Infiltration in Renal Surgery
Status: UNKNOWN
Conditions: Postoperative Pain
Interventions: DRUG: local wound infiltration plus usual care|DRUG: usual care only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Clinical Evaluation of the Safety and Performance of FRF for the Treatment and Reduction of Acne Scarring
Status: COMPLETED
Conditions: Acne Scars - Mixed Atrophic and Hypertrophic
Interventions: DEVICE: Venus Viva MD
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PrEP at a Syringe Services Program
Status: ACTIVE_NOT_RECRUITING
Conditions: Hiv|Substance Use Disorders
Interventions: DRUG: Descovy 200Mg 25Mg Tablet|BEHAVIORAL: PrEP
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Testing of a Valsalva Assist Device (VAD) in Healthy Volunteers Performing a Valsalva Manoeuvre
Status: COMPLETED
Conditions: SVT|Vagal Bradycardia
Interventions: DEVICE: Supine VM VAD|DEVICE: Supine VAD manometer|OTHER: Modified VM VAD|OTHER: Modified VM Manonmeter
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Vinflunine Plus Trastuzumab in Human Epidermal Growth Factor Receptor 2 (HER2neu) Over-Expressing Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Neoplasms|Breast Cancer
Interventions: DRUG: Vinflunine|DRUG: Trastuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Interoceptive Intervention for Pulmonary Hypertension
Status: NOT_YET_RECRUITING
Conditions: Interoception|Pulmonary Hypertension
Interventions: OTHER: interoceptive group based intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Subscapularis Tears in Large to Massive Rotator Cuff Tear
Status: UNKNOWN
Conditions: Massive Rotator Cuff Tears
Interventions: PROCEDURE: arthroscopic reapir of subscapularis tendon|PROCEDURE: arthroscopic debridement of subscapularis tendon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of IBI362 in Participants With Obesity or Overweight
Status: COMPLETED
Conditions: Obesity Or Overweight
Interventions: DRUG: Placebo|DRUG: IBI362
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Identification of Null Allelic Variant of CYP2C8 In A Korean Population
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Rosiglitazone|GENETIC: CYP2C8 genotype
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Integrated Collaborative Care Teams for Youth With Mental Health and/or Addiction Challenges (YouthCan IMPACT)
Status: ACTIVE_NOT_RECRUITING
Conditions: Mental Disorders|Addiction
Interventions: BEHAVIORAL: Integrated Collaborative Care Team (ICCT)|OTHER: Treatment as Usual (TAU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing the Efficacy and Safety of Abciximab, an Anti-Platelet Therapy, in Combination With Two Different Heparin Regimens in Patients Undergoing Percutaneous Coronary Intervention.
Status: COMPLETED
Conditions: Angioplasty, Transluminal, Percutaneous Coronary
Interventions: DRUG: Placebo|DRUG: Heparin|DRUG: Abciximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial To Evaluate the Efficacy and Safety of CKD-397 in Benign Prostatic Hyperplasia Patients
Status: COMPLETED
Conditions: Benign Prostatic Hyperplasia
Interventions: DRUG: Tamsulosin 0.2mg|DRUG: Tadalafil 5mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: PENG Block vs FNB + ONB in Patients Undergoing Hip Fracture Surgery With Contraindications to Neuraxial Anesthesia
Status: COMPLETED
Conditions: Hip Fractures|Pain, Postoperative|Coagulopathy|Comorbidities and Coexisting Conditions
Interventions: PROCEDURE: PENG BLOCK|PROCEDURE: Femoral Nerve Block|PROCEDURE: Obturator Nerve Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Severe Pneumonia Diagnostic in Pediatric Population by Lung Ultrasonography and Procalcitonin
Status: COMPLETED
Conditions: Pneumonia Childhood
Interventions: DIAGNOSTIC_TEST: Lung ultrasonography (LUS) or Chest X ray (CXR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Single Dose Study to Assess the Regional Absorption and Bioavailability of 100mg GSK2190915A
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: GSK2190915 100mg milled tablet|DRUG: [14C] radiolabelled GSK2190915 solution|DRUG: GSK2190915 100mg milled tablet administered to the proximal small bowel.|DRUG: GSK2190915 100mg milled tablet administered to the distal small bowel.|DRUG: GSK2190915 100mg enteric-coated tablet.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Outcome of Laparoscopic Total Mesorectal Excision Versus Open Technique in Management of Rectal Carcimoma
Status: RECRUITING
Conditions: Rectal Carcinoma
Interventions: PROCEDURE: total mesorectal excision in rectal carcinoma
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial to Study the Effects of Sensoril® for Patients With Generalized Anxiety Disorder
Status: COMPLETED
Conditions: Generalized Anxiety Disorder
Interventions: DRUG: Sensoril®|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Mirabegron Versus Tamsulosin Versus Solifenacin for Treatment of Ureteral Stents-Related Symptoms
Status: UNKNOWN
Conditions: Ureteral Stent|Stent Related Symptoms
Interventions: DRUG: Mirabegron 50 MG|DRUG: Tamsulosin|DRUG: Solifenacin Succinate 10 MG|DRUG: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: The Ideal Time Interval Between Repeated Shock Wave Lithotripsy Sessions For Renal Stones: A Randomized Controlled Trial
Status: UNKNOWN
Conditions: Ideal Time Interval
Interventions: PROCEDURE: Shock Wave Lithotripsy for renal stone.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Study Using Botulinum Toxin Type A in Patients With Axillary Hyperhidrosis
Status: COMPLETED
Conditions: Hyperhidrosis
Interventions: BIOLOGICAL: Botulinum Toxin Type A
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Home-based Intervention to Promote Mindful Breathing Awareness Through Pursed-lip Breathing Training for COPD Patients
Status: COMPLETED
Conditions: COPD|Emphysema
Interventions: BEHAVIORAL: mindful breathing application|DEVICE: application on a computer tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acute Effects of Squat Protocols in Muscular Power, Postural Sway and Tendinous Thickness.
Status: WITHDRAWN
Conditions: Acute Squat Training Effects
Interventions: OTHER: Squat protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Comparison of E-health vs. In-person Multi-Family Group (MFG)
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder|Schizophrenia and Related Disorders
Interventions: BEHAVIORAL: Web-based multi-family psychoeducational treatment|BEHAVIORAL: In-persons Multi-Family Group Psycho-Education treatment|OTHER: Treatment as usual (TAU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Collision of Three Global Pandemics: the Effect of Tuberculosis and HIV on the Epidemiological, Clinical, Virological and Immunological Trajectory of COVID-19 in Botswana and Namibia
Status: RECRUITING
Conditions: COVID-19|HIV Seropositivity|Tuberculosis, Pulmonary|Tuberculosis Infection
Interventions: DIAGNOSTIC_TEST: Covid-19, TB and HIV diagnosis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Clinical Trial to Test the Saftey and Success Rate for a Cerrumen Cleaning Device - "Wondertip".
Status: UNKNOWN
Conditions: External Ear Disorder
Interventions: DEVICE: removing cerumen from external ear (Wondertip)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dexamethasone Versus Placebo in Optimizing the Postoperative Period After Laparoscopic Inguinal Hernia Repair
Status: COMPLETED
Conditions: Inguinal Hernia|Femoral Hernia
Interventions: DRUG: Dexamethasone|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Neurocognitive Effects of Non-Invasive Near-Infrared Light Stimulation
Status: RECRUITING
Conditions: Attention Deficit Hyperactivity Disorder|Attention Difficulties|Attention Deficit|Cognitive Deficit|Wellness
Interventions: DEVICE: Transcranial photobiomodulation|DEVICE: Sham transcranial photobiomodulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Annona Muricata Leaves on Colorectal Cancer Patients and Colorectal Cancer Cells
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DIETARY_SUPPLEMENT: Annona muricata extract|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Doxorubicin and Trabectedin in First Line Treatment on Patients With Metastatic Leiomyosarcoma
Status: COMPLETED
Conditions: Uterus Leiomyosarcoma|Soft Tissue Leiomyosarcoma
Interventions: DRUG: Doxorubicin|DRUG: Trabectedin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT