pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Curative Study of Chinese Traditional Medicine to Treat Lung Cancer
Status: UNKNOWN
Conditions: Cancer
Interventions: DRUG: JinFuKang|DRUG: XingZaoRuanJian|DRUG: pemetrexed,docetaxel,gemcitabine,paclitaxel or vinorelbine combined with carboplatin、cis-platinum or nedaplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effects of Topical Calcium Glycerophosphate on Surgical Wound Healing and Residual Scarring
Status: COMPLETED
Conditions: Wound Healing|Scarring
Interventions: OTHER: Topical calcium glycerophosphate lotion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Analgesic Efficacy of Saphenous Nerve Block in Total Knee Replacement
Status: COMPLETED
Conditions: Post Operative Pain
Interventions: PROCEDURE: SNB Saphenous Nerve Block|PROCEDURE: NSNB Non Saphenous Nerve Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fingernails in Evaluating Bone Health in Postmenopausal Women With Breast Cancer Undergoing Hormone Therapy on Clinical Trial IBCSG-1-98
Status: TERMINATED
Conditions: Breast Cancer|Osteoporosis
Interventions: PROCEDURE: spectroscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Netupitant and Palonosetron Hydrochloride in Preventing Chemotherapy Induced Nausea and Vomiting in Patients With Cancer Undergoing BEAM Conditioning Regimen Before Stem Cell Transplant
Status: COMPLETED
Conditions: Malignant Neoplasm
Interventions: DRUG: Netupitant|DRUG: Palonosetron Hydrochloride|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: PErirenal Adipose Tissue and RenaL Hemodynamics in Patients With Heart Failure With Preserved Ejection Fraction
Status: UNKNOWN
Conditions: Heart Failure With Preserved Ejection Fraction|Obesity|Renal Insufficiency
Interventions: RADIATION: 3.7 mS, CT radiation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Drug-Drug Interaction Study of Evobrutinib and Transporter Substrates
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Evobrutinib|DRUG: Digoxin|DRUG: Metformin|DRUG: Rosuvastatin|DRUG: Sumatriptan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stereotactic Ablative Radiotherapy (SABR) for the Treatment of Patients With Metastatic Cancer, ID-COMET Trial
Status: NOT_YET_RECRUITING
Conditions: Oligometastasis|Lung Cancer|Colo-rectal Cancer|Prostate Cancer
Interventions: PROCEDURE: Stereotactic Ablative Radiotherapy|OTHER: Best Practice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bicalutamide and Abemaciclib in Inoperable or Metastatic Androgen Receptor-positive Triple-negative Breast Cancer
Status: RECRUITING
Conditions: Triple Negative Breast Neoplasms
Interventions: DRUG: Abemaciclib|DRUG: Bicalutamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility of Process-based Therapy in a Naturalistic Setting
Status: RECRUITING
Conditions: Depressive Disorder|Anxiety Disorder
Interventions: OTHER: Process-based Cognitive Behavioral Therapy (PBT)|OTHER: Routine practice (r-PT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Tolerability and Explore the Efficacy of Zonisamide as add-on Therapy in Elderly Patients With Refractory Partial Seizures
Status: TERMINATED
Conditions: Epilepsy
Interventions: DRUG: Zonisamide at targeted daily doses of 100-500 mg/day|DRUG: Placebo administered to match targeted daily doses of 100-500 mg/day
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Real-Time Functional Magnetic Resonance Imaging Neurofeedback for Regulation of Psychophysiological Functions
Status: COMPLETED
Conditions: Stress|Blood Pressure
Interventions: OTHER: real-time functional magnetic resonance imaging neurofeedback (RT-fMRI-NF)|BEHAVIORAL: Ambulatory Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Safety of Use of Platinum Based Doublet Chemotherapy Plus Antiangiogenesis and Immune Checkpoint Inhibitors in Patients With Advanced Non-squamous Non-small Cell Lung Cancer
Status: UNKNOWN
Conditions: Advanced Non-squamous Non-small Cell Lung Cancer
Interventions: DRUG: Antiangiogenesis Agents|DRUG: Immune checkpoint inhibitor
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Confirmatory Phase II Study of Blinatumomab (MT103) in Patients With Minimal Residual Disease of B-precursor Acute Lymphoblastic Leukemia (ALL)
Status: COMPLETED
Conditions: B-cell Acute Lymphoblastic Leukemia
Interventions: DRUG: Blinatumomab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Descriptive Evaluation of Expulsive Efforts During Pregnancy in Term Nulliparous Women by Measurement of Intra Bladder Pressure: Pilot Observational Study.
Status: UNKNOWN
Conditions: Perineal Tear
Interventions: PROCEDURE: Recording of expulsive efforts by connection of a pressure sensor to the women's bladder probe
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Tamsulosin Assisted Ureteral Access Sheath Insertion
Status: UNKNOWN
Conditions: Renal Stone|Retrograde Intrarenal Surgery|Urolithiasis
Interventions: DRUG: Tamsulosin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Certolizumab Pegol in Subjects With Adult Onset Active and Progressive Psoriatic Arthritis
Status: COMPLETED
Conditions: Arthritis, Psoriatic
Interventions: BIOLOGICAL: CZP 200 mg Q2W|BIOLOGICAL: CZP 400 mg Q4W|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: CYP2C19 Genotype-Guided P2Y12 Receptor Inhibitor Selection After Complex Percutaneous Coronary Intervention
Status: RECRUITING
Conditions: ACS - Acute Coronary Syndrome|CYP2C19 Polymorphism
Interventions: DRUG: CYP2C19 Genotype Guided DAPT|DRUG: Conventional DAPT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study Evaluating the Impact of Delay Between Administration of Inmazeb Administration and Vaccination by Ervebo on Vaccine Immune Response on Healthy Volunteers
Status: UNKNOWN
Conditions: Ebola Virus Disease
Interventions: BIOLOGICAL: Ervebo|DRUG: Inmazeb
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effect of Diclofenac Potassium Insitu Gel Vs Calcium Hydroxide as Intra-canal Medications on Post-operative Pain and Anti-bacterial Effect
Status: UNKNOWN
Conditions: Post Operative Pain
Interventions: DRUG: Diclofenac Potassium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Spot Sign for Predicting and Treating ICH Growth Study
Status: COMPLETED
Conditions: Intracerebral Hemorrhage
Interventions: DRUG: recombinant activated factor VII|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Dexmedetomidine on Acute Kidney Injury Following Living Donor Liver Transplantation
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Kidney Injury|Liver Diseases
Interventions: DRUG: Dexmedetomidine|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: A Phase 3 Single Center Study of Islet Transplantation in Non-uremic Diabetic Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Type 1 Diabetes|Severe Hypoglycemic Unawareness
Interventions: BIOLOGICAL: Islet Cell Transplant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Hormone and Radiation Therapy Followed by Radical Prostatectomy in Patients With High-Risk Prostate Cancer
Status: RECRUITING
Conditions: Prostate Cancer
Interventions: RADIATION: radiation therapy|DRUG: Goserelin 3.6 MG|PROCEDURE: radical prostatectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BRCA 1/2 Mutation in Korean Patients With Epithelial Ovarian Cancer
Status: COMPLETED
Conditions: To Investigate the Prevalence of BRCA 1/2 Mutation Among Ovarian Cancer
Interventions: GENETIC: Ion AmpliSeq BRCA 1/2 Panel (Life Technologies, Carlsbad, CA, USA) ,Ion PGM platform
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Determine Pharmacokinetic Characteristics of LY03010 Versus INVEGA SUSTENNA® in Schizophrenia Patients
Status: COMPLETED
Conditions: Schizo Affective Disorder|Schizophrenia|Schizoaffective Disorder
Interventions: DRUG: LY03010|DRUG: Invega Sustenna 156 MG in 1 ML Prefilled Syringe
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Efficacy Between Transurethral Coagulation and Transurethral Resection of Ulcer in Bladder Pain Syndrome Patients
Status: COMPLETED
Conditions: Bladder Pain Syndrome
Interventions: PROCEDURE: Transurethral Coagulation (TUC)|PROCEDURE: Transurethral Resection(TUR)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Continuation Study To Monitor The Long Term Safety Of Patients Completing Protocols ACU-P08-020/020A
Status: COMPLETED
Conditions: Presbyopia
Interventions: DEVICE: AcuFocus Corneal Inlay ACI 7000 PDT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Cervical Osteopathic Manipulation in Patients With Whiplash
Status: NOT_YET_RECRUITING
Conditions: Whiplash
Interventions: PROCEDURE: RHB Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Oral Metolazone and Intermittent Intravenous Furosemide Versus Continuous Infusion Furosemide in Acute Heart Failure
Status: TERMINATED
Conditions: Acute Decompensated Heart Failure
Interventions: DRUG: Addition of oral Metolazone|DRUG: Furosemide dose escalation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Red Cell Rejuvenation for the Attenuation of Transfusion Associated Organ Injury in Cardiac Surgery
Status: WITHDRAWN
Conditions: Organ Failure, Multiple|Inflammation|Sepsis
Interventions: DEVICE: rejuvesol Solution|OTHER: Standard Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Immunogenicity and Safety Study of GSK Biologicals' Influenza Vaccine When Administered in Children
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Influenza vaccine GSK2321138A|BIOLOGICAL: FluarixTM|BIOLOGICAL: Influenza vaccine GSK2604409A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study to Assess the Safety, Tolerability, And Pharmacokinetics of Staccato Alprazolam in Healthy Japanese, Chinese, and Caucasian Participants
Status: COMPLETED
Conditions: Healthy Study Participants
Interventions: DRUG: Alprazolam|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Surgical Treatments Outcomes Project for Dysfunctional Uterine Bleeding (STOP-DUB)
Status: COMPLETED
Conditions: Menorrhagia|Uterine Bleeding
Interventions: PROCEDURE: hysterectomy|PROCEDURE: endometrial ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: A Study of ASP4070 to Confirm Safety and Immunological Response in Patients With Pollen Allergy
Status: COMPLETED
Conditions: Cedar Pollinosis
Interventions: DRUG: ASP4070|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Pilot Study of the Immunologic Reconstitution in HIV-1 Infected Children Receiving Highly Active Antiretroviral Therapy With Combination Ritonavir, Nevirapine and Stavudine
Status: COMPLETED
Conditions: HIV Infection
Interventions: DRUG: Ritonavir|DRUG: Nevirapine|DRUG: Stavudine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Electrophysiological Biomarkers of Chemotherapy-related Cognitive Impairment and Recovery
Status: COMPLETED
Conditions: Myelodysplastic Syndrome|Effects of Chemotherapy|Mild Cognitive Impairment|Multiple Myeloma|Non-hodgkin Lymphoma|Chronic Lymphocytic Leukemia|Acute Lymphoid Leukemia|Chronic Myeloid Leukemia|Acute Myeloid Leukemia
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Mid-Transverse Process to Pleural (MTP) Block and Erector Spinal Plan (ESP) Block in Spinal Surgery
Status: COMPLETED
Conditions: Postoperative Pain|Anesthesia, Regional|Spinal Stenosis
Interventions: BEHAVIORAL: MTP block|BEHAVIORAL: ESP block|BEHAVIORAL: No Block group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Spatial Repellent Products for Control of Vector Borne Diseases - Malaria - Indonesia
Status: COMPLETED
Conditions: Malaria
Interventions: DEVICE: Spatial Repellent product with active ingredient (SHIELD)|DEVICE: Active ingredient|DEVICE: Spatial Repellent product without active ingredient (SHIELD)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Combined Treatment of Manual Therapy and Nervous Vagus Stimulation in Patients With Myogenic Temporomandibular Disorders
Status: RECRUITING
Conditions: Temporomandibular Joint Disorders|Pain
Interventions: OTHER: Manual therapy and vagus nerve stimulation|OTHER: Manual therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acceptance-based Intervention at Colorectal Cancer Patients
Status: UNKNOWN
Conditions: Colorectal Neoplasms|Acceptance Process|Pain, Procedural
Interventions: BEHAVIORAL: ACCEPTANCE-BASED INTERVENTION
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: LILRB4 STAR-T Cells in the Treatment of Relapsed/Refractory Acute Myeloid Leukemia
Status: UNKNOWN
Conditions: Relapsed/Refractory Acute Myeloid Leukemia
Interventions: BIOLOGICAL: LILRB4 STAR-T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination of Conditioned Medium and Umbilical Cord-Mesenchymal Stem Cells Therapy for Acute Stroke Infarct
Status: UNKNOWN
Conditions: Ischemic Stroke
Interventions: BIOLOGICAL: Conditioned Medium|BIOLOGICAL: Umbilical Cord Mesenchymal Stem Cells|PROCEDURE: Neurologic and Neutrophic Drugs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I Safety and Immunogenicity Trial of the Facilitated HIV-1 Gag-Pol DNA Vaccine (APL-400-047, Apollon, Inc.) Given Intramuscularly by Needle and Syringe or Biojector 2000 Needle-Free Jet Injection System in HIV-1 Uninfected Adult Volunteers
Status: COMPLETED
Conditions: HIV Infections
Interventions: BIOLOGICAL: APL 400-047|DRUG: Bupivacaine hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Evolving Treatment Modalities for Management of Patients Suffering From Disc Displacement With Reduction
Status: COMPLETED
Conditions: Temporomandibular Joint Disc Displacement, With Reduction
Interventions: DEVICE: Low level laser therapy|DRUG: Botulinum toxin type A|DEVICE: Anterior repositioning appliance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Targeting Residual Activity By Precision, Biomarker-Guided Combination Therapies of Multiple Sclerosis (TRAP-MS)
Status: RECRUITING
Conditions: Multiple Sclerosis
Interventions: DRUG: Pioglitazone|DRUG: clemastine fumarate|DRUG: Dantrolene|DRUG: Pirfenidone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Blockade Efficacy of Buprenorphine/Naloxone For Opioid Dependence
Status: COMPLETED
Conditions: Opioid-Related Disorders
Interventions: DRUG: Buprenorphine/naloxone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: SAS-J Compared to OAGB and LSG as a Treatment for Morbid Obesity
Status: COMPLETED
Conditions: Morbid Obesity
Interventions: PROCEDURE: SAS-JB|PROCEDURE: OAGB|PROCEDURE: LSG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aromatherapy Randomization of Pain Management in Adults
Status: SUSPENDED
Conditions: Back Pain|Back Pain, Low|Sciatica
Interventions: OTHER: Rose oil|OTHER: Almond Oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Kinesio Taping Compared to Exercise Intervention for Round Shoulder Subjects With Impingement Syndrome
Status: COMPLETED
Conditions: Shoulder Impingement Syndrome (SIS); Round Shoulder Posture (RSP)
Interventions: OTHER: kinesio taping|OTHER: exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 2a Study to Assess CIVI 007 in Patients on a Background of Statin Therapy
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DRUG: CIVI 007
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: PLAsticity, Security and Tolerance to Intermittent Hypoxic Conditioning Following Stroke
Status: WITHDRAWN
Conditions: Stroke, Ischemic|Stroke Sequelae
Interventions: DRUG: Hypoxia, intermittent|OTHER: Normoxia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Feasibility Study of Personalized Trials to Improve Sleep Quality
Status: COMPLETED
Conditions: Sleep Disturbance
Interventions: DIETARY_SUPPLEMENT: Melatonin 3 mg|DIETARY_SUPPLEMENT: Melatonin 0.5 mg|OTHER: Cellulose placebo pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Neoadjuvant Vismodegib in Patients With Large and/or Recurrent Resectable Basal Cell Carcinoma
Status: COMPLETED
Conditions: Basal Cell Carcinoma
Interventions: DRUG: Vismodegib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility, Safety and Utility of Endomicroscopy to Study the Intestines of Unsedated Infants at University of Virginia (UVa)
Status: ENROLLING_BY_INVITATION
Conditions: Healthy
Interventions: DEVICE: Transnasal introduction tube
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Efficacy and Safety of Temazepam in HIV Seropositive Patients With Insomnia
Status: COMPLETED
Conditions: Insomnia
Interventions: DRUG: Temazepam|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of VIR-2218 in Healthy Subjects and Patients With Chronic Hepatitis B
Status: COMPLETED
Conditions: Chronic Hepatitis B
Interventions: DRUG: VIR-2218|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Preliminary Efficacy, Safety, and PK of Subcutaneous JS005 in Chinese Adult Patients With Active Nr-axSpA
Status: UNKNOWN
Conditions: Non-radiographic Axial Spondyloarthritis
Interventions: BIOLOGICAL: JS005|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Anti-PD1 Antibody Toripalimab Combined With Gemox as First-line Therapy in Late-stage Intrahepatic Cholangiocarcinoma
Status: UNKNOWN
Conditions: Intrahepatic Cholangiocarcinoma
Interventions: DRUG: Gemox combimed PD1 antibody
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Development of a Test Battery for Measurement of Knee Function in Patients With Patellar Instability
Status: COMPLETED
Conditions: Patella|Joint Instability|Patellofemoral Joint Dislocation
Interventions: OTHER: Return to Sport testbattery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Clinical Efficacy of 10% Arginine Bicarbonate Prophylaxis Paste
Status: COMPLETED
Conditions: Hypersensitivity
Interventions: DEVICE: Arginine/Calcium Carbonate|DEVICE: Nupro - Fluoride Free
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Anatomical Results and Sexual Functions After Unilateral and Bilateral Laparoscopic Suture Sacro-hysteropexy Operations
Status: RECRUITING
Conditions: Pelvic Organ Prolapse
Interventions: PROCEDURE: unilateral suture sacro-hysteropexy|PROCEDURE: bilateral suture sacro-hysteropexy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessing the Impact of a Patient Education Platform to Augment the Informed Consent Process for Obstetrics and Gynecology Procedures
Status: UNKNOWN
Conditions: Hysteroscopy Surgery|Informed Consent
Interventions: BEHAVIORAL: Patient Education Platform
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Safety and Vascular Remodelling After BVS Implantation for Stenotic or Occluded Lesions in Children and Young Adults With KD.
Status: UNKNOWN
Conditions: Kawasaki Disease
Interventions: DEVICE: Bioresorbable Vascular Scaffold
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial to Assess the Pain-control Efficacy of Intra-articular Toradol Compared to Oral NSAIDs
Status: WITHDRAWN
Conditions: Arthritic Knee Pain
Interventions: DRUG: Toradol|DRUG: Oral NSAID
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ranolazine in Ischemic Cardiomyopathy
Status: COMPLETED
Conditions: Cardiomyopathy|Chest Pain|Dyspnea
Interventions: DRUG: Ranexa|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Tislelizumab（Anti PD-1), Lenvatinib and GEMOX Transformation in the Treatment of Potentially Resectable, Locally Advanced Biliary Tract Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Biliary Tract Cancer|PD-1 Antibody|Gemox|Lenvatinib
Interventions: DRUG: PD-1+Lenvatinib+GEMOX
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Efficacy of Tranexamic Acid Mesotherapy Versus 0.9% Normal Saline for Melasma
Status: COMPLETED
Conditions: Effect of Drugs|Adverse Effects of Medical Drugs
Interventions: DRUG: Tranexamic Acid|DRUG: 0.9% Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Treating Patients With a History of Non-Life Threatening Allergic Reaction to Penicillin With Penicillin
Status: TERMINATED
Conditions: Penicillin Allergy
Interventions: DRUG: Penicillin test and challenge
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of Dupilumab Administered to Adult Patients With Moderate-to-Severe Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: Dupilumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Leg Fluid Shift in Patients With Chronic Heart Failure and Obstructive or Central Sleep Apnea
Status: COMPLETED
Conditions: Obstructive Sleep Apnoea|Central Sleep Apnoea|Cheyne Stokes Respiration
Interventions: DIAGNOSTIC_TEST: Multi Frequency Bioimpedance Analysis (mfBIA)|DIAGNOSTIC_TEST: Polysomnography/Polygraphy (PSG/PG)|DIAGNOSTIC_TEST: Capillary Blood Gas Analysis (CBGA)|DIAGNOSTIC_TEST: Tilting Table with Hemodynamic Monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Randomized, Controlled, Crossover Study to Assess the Glucose and Insulin Excursions of a Test Fiber
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: Control digestible carbohydrate|OTHER: Test resistant starch type 4
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Study to Assess the Effect of Dexpramipexole in Adolescents and Adults With Severe Eosinophilic Asthma (EXHALE-3)
Status: RECRUITING
Conditions: Eosinophilic Asthma|Asthma; Eosinophilic|Asthma
Interventions: DRUG: Dexpramipexole Dihydrochloride|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Does Menstrual Hygiene Matter? Investigating the Impact of a Menstrual Hygiene Program on Ugandan Girls' School Absenteeism
Status: COMPLETED
Conditions: Menstrual Hygiene Management
Interventions: DEVICE: Irise Easy Pad & Menstrual Health Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy of Vaginal Microbiota Transplant (VMT) in Women With Bacterial Vaginosis (BV)
Status: WITHDRAWN
Conditions: Bacterial Vaginosis
Interventions: DRUG: Cervicovaginal secretions|DRUG: Metronidazole gel|DIAGNOSTIC_TEST: Screening tests|BEHAVIORAL: Activities restriction|OTHER: Sterile Saline placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effectiveness of Music Therapy in Social Skill Intervention for Children With ASD/ID
Status: COMPLETED
Conditions: Autism Spectrum Disorder|Intellectual Disability
Interventions: OTHER: Music therapy|BEHAVIORAL: Behavioral-based social skill training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Administration of Increased Dose of GnRH Antagonist for Coasting for Decreasing the Risk for Ovarian Hyperstimulation Syndrome( OHSS)
Status: WITHDRAWN
Conditions: Administration of Increased Dose of GnRH Antagonist for Coasting for Decreasing the Risk for Ovarian Hyperstimulation Syndrome( OHSS)
Interventions: DRUG: Cetrotide
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose:
Clinical trial: Comparison of Topical 0.15% Gancyclovir Gel Versus 0.3% Hypromellose Gel for the Treatment of Herpes Zoster Keratitis
Status: TERMINATED
Conditions: Herpes Zoster Keratitis
Interventions: DRUG: gancyclovir gel|DRUG: Hypromellose gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Tacrolimus Extended-Release (Envarsus XR) to Tacrolimus Immediate-Release in Human Leukocyte Antigen (HLA) Sensitized Kidney Transplant Recipients
Status: COMPLETED
Conditions: Kidney Transplant Rejection
Interventions: DRUG: Extended-release tacrolimus|DRUG: Immediate-release tacrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tiraglolumab Atezolizumab and Chemoradiotherapy in Localized Anal Carcinoma (TIRANUS)
Status: RECRUITING
Conditions: Squamous Cell Carcinoma of the Anal Canal
Interventions: DRUG: Atezolizumab plus Tiraglolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Avelumab, Palbociclib and Axitinib in Advanced RCC
Status: WITHDRAWN
Conditions: Advanced Clear Cell Renal Cell Carcinoma
Interventions: DRUG: Axitinib|DRUG: Palbociclib|DRUG: Avelumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Itolizumab in COVID-19 Complications
Status: COMPLETED
Conditions: Acute Respiratory Distress Syndrome|Cytokine Release Syndrome|Covid19
Interventions: DRUG: Itolizumab IV infusion|DRUG: Best supportive care (BSC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Association Analysis of Aerobic Capacity and Expiratory Forced Vital Capacity in Overweight and Obese Adults After Submaximal Exercise Training of Three Weeks
Status: UNKNOWN
Conditions: Overweight and Obese Adults
Interventions: BEHAVIORAL: submaximal exercise testing according to ACSM guidelines
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Clinical Study of AK1820 (Isavuconazonium Sulfate) for the Treatment of Deep Mycosis
Status: COMPLETED
Conditions: Deep Mycosis
Interventions: DRUG: AK1820|DRUG: Voriconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Proton Re-Irradiation for Recurrent Head and Neck Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Head and Neck Cancer
Interventions: RADIATION: conventionally fractionated full dose re-irradiation|RADIATION: hypofractionated palliative re-irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of PMI-150 (Intranasal Ketamine) for the Treatment of Breakthrough Pain in Cancer Patients
Status: TERMINATED
Conditions: Pain|Cancer
Interventions: DRUG: PMI-150 (intranasal ketamine)|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial to Evaluate the Effect of Eslicarbazepine Acetate on Cardiac Repolarization
Status: COMPLETED
Conditions: Epilepsy
Interventions: DRUG: BIA 2-093|DRUG: Moxifloxacin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antimicrobial Photodynamic Therapy as an Adjunct Treatment for Periodontal Disease in Down's Syndrome Patients
Status: COMPLETED
Conditions: Periodontal Diseases
Interventions: PROCEDURE: Antimicrobial photodynamic therapy|PROCEDURE: Scaling and root planning|DEVICE: red laser|DRUG: methylene blue dye
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Endovascular QUANTUM LP™ Stent Graft System in Abdominal Aortic Aneurysms (AAA)
Status: COMPLETED
Conditions: Abdominal Aortic Aneurysm
Interventions: DEVICE: QUANTUM LP™ STENT GRAFT SYSTEM|PROCEDURE: Open surgical repair
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Electroacupuncture on Post-stroke Urinary Retention
Status: TERMINATED
Conditions: Urinary Retention|Stroke, Complication
Interventions: DEVICE: Electroacupuncture (EA)|DEVICE: Sham electroacupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Gemcitabine and Cisplatin With Ivosidenib or Pemigatinib for the Treatment of Unresectable or Metastatic Cholangiocarcinoma
Status: TERMINATED
Conditions: Advanced Cholangiocarcinoma|Metastatic Cholangiocarcinoma|Unresectable Cholangiocarcinoma
Interventions: DRUG: Cisplatin|DRUG: Gemcitabine|DRUG: Ivosidenib|DRUG: Pemigatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Changes in Coagulation in Colorectal Cancer Patients Undergoing Surgical Treatment
Status: COMPLETED
Conditions: Peritoneal Metastases|Peritoneal Carcinomatosis|Colorectal Neoplasms Malignant|Intestinal Neoplasms|Cytoreductive Surgery|Venous Thromboembolism|Bleeding|Laparoscopic Surgery|Coagulation|Surgical Procedures, Operative|Postoperative Complications|Laparoscopy|Minimally Invasive Surgical Procedures|Surgical Oncology
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: 14-day PCAB-based High-dose Dual Therapy and14-day PCAB-based Triple Therapy vs 14-day PPI-based Reverse Hybrid Therapy
Status: RECRUITING
Conditions: Helicobacter Pylori Eradication
Interventions: DRUG: Vonoprazan and Amoxicillin|DRUG: Vonoprazan, Amoxicillin and Clarithromycin|DRUG: Rabeprazole, Amoxicillin, Clarithromycin and Metronidazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Placebo-controlled Study Evaluating the Efficacy and Safety of Vardenafil in Subjects With Erectile Dysfunction
Status: COMPLETED
Conditions: Erectile Dysfunction
Interventions: DRUG: Levitra (Vardenafil, BAY38-9456)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized, Controlled Study of Intravenous Ganciclovir Therapy for Peripheral Cytomegalovirus Retinitis in Patients With AIDS
Status: COMPLETED
Conditions: Cytomegalovirus Retinitis|HIV Infections
Interventions: DRUG: Ganciclovir
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Working With Doctors and Pharmacists to Help Parents Give Children's Liquid Medicines Safely
Status: RECRUITING
Conditions: Medication Dosing Error
Interventions: OTHER: EHR-Based Approach
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Reducing Postoperative Bleeding After Hysterectomy Via Independent Closure of Vaginal Cuff Angles
Status: COMPLETED
Conditions: Postoperative Bleeding|Patient Satisfaction|Complications|Operative Time
Interventions: PROCEDURE: Angle stitch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Evolocumab on the Effects of Clopidogrel in Patients With High On-Treatment Platelet Reactivity
Status: COMPLETED
Conditions: Atherosclerotic Cardiovascular Disease
Interventions: DRUG: Evolocumab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Melpida: Recombinant Adeno-associated Virus (Serotype 9) Encoding a Codon Optimized Human AP4M1 Transgene (hAP4M1opt)
Status: RECRUITING
Conditions: Spasticity, Muscle|Microcephaly|Intellectual Deficiency|Growth Retardation|SPG50|Spastic Paraplegia
Interventions: BIOLOGICAL: MELPIDA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Crossover Study With Hexalacton in Patients With Type 1 Diabetes and Microalbuminuria
Status: UNKNOWN
Conditions: Diabetes Mellitus|Nephropathy|Blood Pressure
Interventions: DRUG: Spironolacton (hexalacton(R))|DRUG: placebo tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I Study Priming With an Inactivated A/H7N9 Influenza Virus Vaccine With or Without MF59 Adjuvant Followed by Live Attenuated A/H7N9 Influenza Virus Vaccine
Status: COMPLETED
Conditions: Avian Influenza|Immunisation
Interventions: BIOLOGICAL: Influenza Virus Vaccine, Live Attenuated H7N9 Anhui 2013/AA ca|BIOLOGICAL: Influenza Virus Vaccine, Monovalent A/H7N9 A/Shanghai/2/2013|DRUG: MF59 adjuvant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Neuroimaging Correlates and Feasibility of Transcranial Magnetic Stimulation (TMS) to Improve Smoking Cessation Outcomes in Veterans With Comorbid PTSD
Status: RECRUITING
Conditions: Tobacco Use Disorder
Interventions: DEVICE: active repetitive transcranial magnetic stimulation|DEVICE: sham repetitive transcranial magnetic stimulation|BEHAVIORAL: cognitive behavioral therapy for smoking cessation|DRUG: nicotine replacement therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Personalized Breathing Exercise Device in Patients With COPD
Status: NOT_YET_RECRUITING
Conditions: Chronic Obstructive Pulmonary Disease|Inspiratory Muscle Training|Expiratory Muscle Training
Interventions: DEVICE: Respiratory Muscle Training Device|DEVICE: Personalized Breathing Exercise Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Demonstration of Bioequivalence of Empagliflozin and Metformin Given in One Tablet Compared to the Intake of Single Tablets
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Empagliflozin|DRUG: Empagliflozin + Metformin|DRUG: Metformin|DRUG: Metformin|DRUG: Empagliflozin + Metformin|DRUG: Empagliflozin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Erector Spinae Plane Block Versus Quadratus Lumborum Block For Postoperative Analgesia After Abdominal Hysterectomy
Status: COMPLETED
Conditions: Anesthesia
Interventions: PROCEDURE: peripheral nerve block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: High-dose Selenium Supplementation in Patients With Left Ventricular Assist
Status: COMPLETED
Conditions: Ventricular Dysfunction, Left
Interventions: DRUG: Selenium Supplement (sodium selenite)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Radical Surgery Followed by Immunotherapy Using Precision T Cells Specific to Multiple Common Tumor-Associated Antigen for the Treatment of Hepatocellular Carcinoma
Status: UNKNOWN
Conditions: Liver Cancer
Interventions: PROCEDURE: Postoperative routine treatment|BIOLOGICAL: DC-PMAT treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Ustekinumab in Chinese Participants With Active Systemic Lupus Erythematosus
Status: WITHDRAWN
Conditions: Lupus Erythematosus, Systemic
Interventions: DRUG: Ustekinumab (approximately 6 mg/kg)|DRUG: Ustekinumab 90 milligram (mg)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Long Term Efficacy and Tolerability of AP707 in Patients With Chronic Pain Due to Traumatic or Post-operative Peripheral Neuropathy
Status: RECRUITING
Conditions: Pain|Pain Syndrome|Pain, Chronic|Chronic Pain|Chronic Pain Syndrome|Neuropathic Pain|Peripheral Neuropathy|Peripheral Neuralgia|Peripheral Nerve Injury|Post Operative Pain|Post-Traumatic Neuralgia|Plexopathy
Interventions: DRUG: Adezunap (AP707)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pembrolizumab + Epacadostat vs Pembrolizumab + Placebo in Recurrent or Progressive Metastatic Urothelial Carcinoma
Status: COMPLETED
Conditions: UC (Urothelial Cancer)
Interventions: DRUG: Pembrolizumab|DRUG: Epacadostat|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety, Pharmacokinetics and Pharmacodynamics Study of RO6811135 in Patients With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus Type 2
Interventions: DRUG: Placebo|DRUG: RO6811135
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Sonography of the Nipple Areolar Complex
Status: RECRUITING
Conditions: Healthy
Interventions: DIAGNOSTIC_TEST: Thin layer conventional ultrasound coupling gel|DIAGNOSTIC_TEST: Thick layer of conventional ultrasound coupling gel|DIAGNOSTIC_TEST: Thin conventional ultrasound coupling gel pad|DIAGNOSTIC_TEST: Thick conventional ultrasound coupling gel pad
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Testing GSK2636771 as a Potential Targeted Treatment in Cancers With PTEN Loss of Expression (MATCH-Subprotocol P)
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Lymphoma|Advanced Malignant Solid Neoplasm|Hematopoietic and Lymphoid Cell Neoplasm|Refractory Lymphoma|Refractory Malignant Solid Neoplasm|Refractory Multiple Myeloma
Interventions: DRUG: PI3K-beta Inhibitor GSK2636771
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Supplementing Iron and Development in Breastfed Infants (SIDBI Study)
Status: UNKNOWN
Conditions: Iron Deficiency
Interventions: DRUG: Iron|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Ridaforolimus (AP23573/MK-8669) in Participants With Taxane-Resistant Androgen-Independent Prostate Cancer (AIPC)(MK-8669-017)
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: ridaforolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Continuous Glucose Monitoring on Course of Glucose in Type 1 Diabetes
Status: COMPLETED
Conditions: Type 1 Diabetes|Hypoglycemia
Interventions: DEVICE: Real time access to current glucose values during CGMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT