pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Comparison of the Effect of Two Types of Physical Exercises in Patients With Heart Failure With Preserved Ejection Fraction
Status: RECRUITING
Conditions: Heart Failure|Physical Exercise|Exercise Capacity|Diastolic Function|Endothelial Function|Arterial Stiffness
Interventions: BEHAVIORAL: Combined exercise|BEHAVIORAL: High interval training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Multi-Center Study of Ibrutinib in Combination With Obinutuzumab Versus Chlorambucil in Combination With Obinutuzumab in Patients With Treatment naïve Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Lymphoma (SLL)
Status: COMPLETED
Conditions: Chronic Lymphocytic Leukemia|Small-Cell Lymphoma
Interventions: DRUG: Ibrutinib|DRUG: Obinutuzumab|DRUG: Chlorambucil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Eltoprazine on Cognitive Impairment Associated With Schizophrenia (CIAS) in Adults
Status: COMPLETED
Conditions: Cognitive Impairment|Schizophrenia
Interventions: DRUG: Eltoprazine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: High-dose Accelerated Theta Burst Stimulation for the Treatment of Alcohol Addiction
Status: RECRUITING
Conditions: Alcohol Dependence
Interventions: DEVICE: high-dose accelerated intermittent theta burst stimulation|DEVICE: sham high-dose accelerated intermittent theta burst stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fiber Tolerability in Children
Status: COMPLETED
Conditions: Signs and Symptoms, Digestive
Interventions: DRUG: Placebo (including Maltodextrin)|DRUG: PROMITOR® (including Maltodextrin)|DRUG: PROMITOR® (including Maltodextrin)|DRUG: PROMITOR® (including Maltodextrin)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Efficacy and Safety of 9MW0813 in Subjects With Diabetic Macular Edema
Status: UNKNOWN
Conditions: Diabetic Macular Edema
Interventions: DRUG: 9MW0813|DRUG: Aflibercept
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Animal Assisted Therapy in a Pediatric Setting
Status: COMPLETED
Conditions: Developmental Delays|Global Developmental Delay|Stroke|Cancers|Seizures Disorders|Behavior Problems|Feeding Disorder|Developmental Delay in Feeding
Interventions: BEHAVIORAL: Animal Assisted Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Clinical Trial to Compare Pharmacokinetics of the "CDFF0318" and "Champix Tab. 1mg"
Status: COMPLETED
Conditions: Smoking Cessation|Pharmacokinetics
Interventions: DRUG: CDFF0318, Champix
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Polyethylene Glycol-Interferon Alfa-2B (PEG-Intron, SCH 54031) Compared to Interferon Alfa-2B in Participants With Chronic Hepatitis C (MK-4031-016)
Status: COMPLETED
Conditions: Hepatitis C
Interventions: BIOLOGICAL: PEG-Intron|BIOLOGICAL: Interferon Alfa-2B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Anlotinib Hydrochloride as Second-line Therapy in Elderly Patients With EGFR Wild-type Lung Adenocarcinoma
Status: UNKNOWN
Conditions: Non-Small-Cell Lung Cancer
Interventions: DRUG: Anlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sleep as a Mechanism of Change in Alcohol Use
Status: RECRUITING
Conditions: Insomnia|Alcohol; Harmful Use
Interventions: BEHAVIORAL: Cognitive Behavioral Therapy for Insomnia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Online Single-Session Interventions on College Student Well-being
Status: COMPLETED
Conditions: Well-Being|Depressive Symptoms|Anxiety|Affect
Interventions: BEHAVIORAL: Multi-component Well-being Intervention|BEHAVIORAL: Study Skills
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study to Evaluate the Effectiveness and Safety of MK-1029 in the Treatment of Persistent Asthma That is Not Controlled With Montelukast (ML) in Adults (MK-1029-011)
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: MK-1029|DRUG: Placebo|DRUG: Montelukast (ML)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Post Anaesthesia Care Hypotension Prevention
Status: NOT_YET_RECRUITING
Conditions: Hypotension During Surgery
Interventions: DEVICE: HPI (using HemoSphere) - guided algorithm|DEVICE: Treatment of hypotension following standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Lifestyle Intervention for Healthy Change
Status: NOT_YET_RECRUITING
Conditions: Overweight and Obesity
Interventions: BEHAVIORAL: Nutrigenomix, personalized dietary plan|BEHAVIORAL: Physical Activity|BEHAVIORAL: Behavioral counseling|BEHAVIORAL: Standard Dietary plan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Exercise Exposure Data Collection in Patients Undergoing Tumor Molecular Profiling
Status: ACTIVE_NOT_RECRUITING
Conditions: Cancer|Carcinoma
Interventions: BEHAVIORAL: Prior Exercise Behavior Questions - Harvard Health Professionals Exercise Questionnaire|BEHAVIORAL: Current Exercise Behavior Questions: International Physical Activity Questionnaire Short Form (IPAQ SF)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: High Intensity Lipid Lowering Following Acute Coronary Syndromes for Persons Living With HIV
Status: COMPLETED
Conditions: HIV Infection|Coronary Heart Disease
Interventions: DRUG: Pravastatin|DRUG: Rosuvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transcranial Near Infrared Radiation and Cerebral Blood Flow in Depression - R33
Status: RECRUITING
Conditions: Major Depressive Disorder
Interventions: DEVICE: Transcranial Photobiomodulator|DEVICE: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Intraperitoneal Dexmedetomidine Versus Ketamine With Bupivacaine For Postoperative Analgesia
Status: COMPLETED
Conditions: Obesity
Interventions: DRUG: normal saline|DRUG: dexmedetomidine|DRUG: Ketamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MBC2OTP Project (Measurement-Based Care Implementation in Community Opioid Treatment Programs)
Status: NOT_YET_RECRUITING
Conditions: Opioid Use Disorder
Interventions: BEHAVIORAL: Measurement Based Care Training and Monthly Consultation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Open Label Study to Assess Safety, PK and Explore Efficacy of OPRX-106 in Patients With Active Mild to Moderate Ulcerative Colitis
Status: UNKNOWN
Conditions: Ulcerative Colitis
Interventions: DRUG: OPRX-106
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Prospective Study of PD-1 Inhibitor Combined With ICE in the Treatment of Relapsed/Refractory Gray Area Lymphoma
Status: UNKNOWN
Conditions: Gray Zone Lymphoma|Relapse/Recurrence|Chemotherapy Effect
Interventions: DRUG: PD-1 inhibitor +ICE
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Research Study of How Oral Semaglutide Tablets Work in Healthy People Who Are Chinese
Status: COMPLETED
Conditions: Healthy Volunteers|Diabetes Mellitus, Type 2
Interventions: DRUG: Oral semaglutide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: IntellO2 vs Manual Control for Optimizing Oxygenation in Infants
Status: COMPLETED
Conditions: Oxygen Titration in Preterm Infants to Manage Lung Disease
Interventions: DEVICE: IntellO2|OTHER: Manual control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Indwelling Pleural Catheters With or Without Doxycycline in Treating Patients With Malignant Pleural Effusions
Status: RECRUITING
Conditions: Pleural Neoplasm
Interventions: DRUG: Doxycycline|DEVICE: Indwelling Catheter|PROCEDURE: Quality-of-Life Assessment|OTHER: Questionnaire Administration|OTHER: Survey Administration
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Alternating Systemic and Hepatic Artery Infusion Therapy As Adjuvant Treatment After Resection of Liver Metastases From Colorectal Cancer
Status: UNKNOWN
Conditions: Resected Liver Metastases From Colorectal Cancer
Interventions: DRUG: Floxuridine (FUDR),Dexamethasone (DXM), Heparin in combination with Oxaliplatin and Capecitabine (CapeOX) or in combination with Oxaliplatin and Leucovorin and 5-FU (mFOLFOX6)|DRUG: Oxaliplatin and Capecitabine (CapeOX) or Oxaliplatin and Leucovorin and 5-FU (mFOLFOX6)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating the Efficacy of Glucocorticoids in Patients With Pre-ACLF-HBV
Status: UNKNOWN
Conditions: Liver Failure|Hepatitis B
Interventions: DRUG: 5 days dexamethasone therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bio-availability Comparison of Three Formulations of Certolizumab Pegol in Healthy Volunteers
Status: COMPLETED
Conditions: Bioavailability Study on Healthy Volunteers
Interventions: BIOLOGICAL: Certolizumab pegol|BIOLOGICAL: Certolizumab pegol|BIOLOGICAL: Certolizumab pegol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of Anti-atherosclerotic and Estrogen-like Activity of Karinat in Perimenopausal Women
Status: COMPLETED
Conditions: Menopausal Syndrome|Atherosclerosis
Interventions: DIETARY_SUPPLEMENT: Karinat|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Computer-Based Training for Cognitive Enhancement: In Home Study
Status: COMPLETED
Conditions: Aging
Interventions: OTHER: Computerized Plasticity-Based Adaptive Cognitive Training|OTHER: Educational DVDs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Imatinib Mesylate in Combination With Pembrolizumab in Patients With Melanoma
Status: RECRUITING
Conditions: Melanoma
Interventions: DRUG: Pembrolizumab and Imatinib mesylate|DRUG: Pembrolizumab and Imatinib mesylate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Interest of Levosimendan in Reducing Weaning Failures of ExtraCorporeal Life Support - ECLS
Status: UNKNOWN
Conditions: Acute Decompensated Heart Failure
Interventions: DRUG: Levosimendan|DRUG: Cernevit
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Neural and Behavioral Effects of Oxytocin in Autism Spectrum Disorders
Status: COMPLETED
Conditions: Autism Spectrum Disorders
Interventions: DRUG: Syntocinon (Oxytocin)|OTHER: Placebo (Physiological water (solution of sodium chloride (NaCl) in water))
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: High Frequency (1000Hz) Spinal Cord Stimulation in Neuropathic Pain Patients With Virgin Back
Status: RECRUITING
Conditions: Neuropathic Pain|Low Back Pain
Interventions: DEVICE: Boston Wavewriter 1000Hz Spinal cord Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Melatonin Associated to Acid Inhibition for Chemoprevention in Barret Esophagus: a Pilot Study
Status: COMPLETED
Conditions: Barrett's Esophagus
Interventions: DRUG: Omeprazole|DRUG: Melatonin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Image-Guided Radiosurgery or Stereotactic Body Radiation Therapy in Treating Patients With Localized Spine Metastasis
Status: COMPLETED
Conditions: Metastatic Cancer|Pain
Interventions: RADIATION: External beam radiation therapy|RADIATION: Radiosurgery/SBRT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Drug Eluting Temporary Spur Stent System vs Percutaneous Balloon Angioplasty for the Treatment of Critical Limb Ischemia
Status: NOT_YET_RECRUITING
Conditions: Critical Limb Ischemia
Interventions: DEVICE: Drug Eluting Temporary Spur Stent System|DEVICE: Percutaneous Transluminal Balloon Angioplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Gemcitabine and Oxaliplatin in Treating Patients With Pancreatic Cancer That Can Be Removed By Surgery
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DRUG: gemcitabine hydrochloride|DRUG: oxaliplatin|GENETIC: protein expression analysis|GENETIC: proteomic profiling|OTHER: diagnostic laboratory biomarker analysis|PROCEDURE: adjuvant therapy|PROCEDURE: neoadjuvant therapy|PROCEDURE: therapeutic conventional surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mindfulness-based Stress Reduction and Cognitive Function in Stress and Aging
Status: COMPLETED
Conditions: Anxiety Disorders|Depression
Interventions: BEHAVIORAL: MBSR|BEHAVIORAL: control (health education)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: COVID-19 Vaccine (ChAdOx1 nCoV-19) Trial in South African Adults With and Without HIV-infection
Status: UNKNOWN
Conditions: Coronavirus
Interventions: BIOLOGICAL: ChAdOx1 nCoV-19|BIOLOGICAL: Normal saline 0.9%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Shaeer's Vein Ligation-II: Internal Pudendal Vein Perineal Ligation For Veno Occlusive Erectile Dysfunction
Status: NOT_YET_RECRUITING
Conditions: Erectile Dysfunction|Erectile Dysfunction Due to Venous Disorder
Interventions: PROCEDURE: Shaeer-II|PROCEDURE: PPI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Does the Presence of Cervical Facet Tropism Affect the Response to Interlaminar Epidural Steroid Injections?
Status: RECRUITING
Conditions: Cervical Disc Herniation|Cervical Radicular Pain|Facet Tropism
Interventions: PROCEDURE: Interlaminar Epidural Steroid Injection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: TIL Therapy in Combination With Checkpoint Inhibitors for Metastatic Ovarian Cancer
Status: COMPLETED
Conditions: Metastatic Ovarian Cancer
Interventions: DRUG: Cyclophosphamide|DRUG: Fludarabine|BIOLOGICAL: TIL infusion|DRUG: Interleukin-2|DRUG: Ipilimumab|DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oxytocin in Spectrum Autism Disorders
Status: COMPLETED
Conditions: Autistic Disorder
Interventions: DRUG: Oxytocin|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: OSTEOAMP Lumbar Fusion Intra-Patient Controlled Study
Status: RECRUITING
Conditions: Lumbar Spine Disease|Lumbar Spondylolisthesis|Lumbar Spine Instability|Lumbar Spondylosis|Degenerative Disc Disease
Interventions: OTHER: OSTEOAMP|DEVICE: Infuse
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Colchicine Use for Primary Prevention of Coronary Artery Disease
Status: NOT_YET_RECRUITING
Conditions: Coronary Artery Disease
Interventions: DRUG: Colchicine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Allogeneic Islet Transplantation for the Treatment of Type 1 Diabetes
Status: UNKNOWN
Conditions: Patients With Type 1 Diabetes
Interventions: PROCEDURE: Allogeneic transplantation of intrahepatic islet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy and Bone Marrow Transplant in Treating Patients With Refractory or Recurrent Ovarian Cancer
Status: COMPLETED
Conditions: Ovarian Cancer
Interventions: DRUG: carboplatin|DRUG: cyclophosphamide|DRUG: mitoxantrone hydrochloride|PROCEDURE: autologous bone marrow transplantation|PROCEDURE: bone marrow ablation with stem cell support
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Topical ASC-J9 Cream for Acne
Status: COMPLETED
Conditions: Acne
Interventions: DRUG: ASC-J9
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hybrid Intraprocedural Imaging Based on 2 Different Imaging Methods
Status: WITHDRAWN
Conditions: Angina Pectoris|Left Ventricular Wall Motion Abnormalities
Interventions: PROCEDURE: 2D-strain echo
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Hemodynamic Instability Prevented With Polaramine® Infusion Before Extracorporeal Circulation
Status: COMPLETED
Conditions: Hemodynamic Instability|Vasoplegic Syndrome
Interventions: DRUG: dexchlorpheniramine (Polaramine®) injection|DRUG: Placebo injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Influence of Desensitizing Agent on Postoperative Sensitivity in Posterior Composite Restoration
Status: COMPLETED
Conditions: Dentin Hypersensitivity
Interventions: OTHER: Hurriseal desensitizer|OTHER: Gluma desensitizer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Randomised Controlled Trial of Vericiguat in Patients With Coronary Microvascular Dysfunction Causing Stable Chest Pain (V-COM)
Status: NOT_YET_RECRUITING
Conditions: Chest Pain
Interventions: DRUG: Vericiguat|DIAGNOSTIC_TEST: Stress Cardiac Magnetic Resonance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation of Blood Glucose Monitoring Systems With Blood Samples From Neonates
Status: COMPLETED
Conditions: Diabetes
Interventions: DEVICE: Contour® NEXT BGMS|DEVICE: Contour® PLUS BGMS|DEVICE: Contour® Next EZ BGMS
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Fecal Microbiota Transplantation in the Treatment of Inflammatory Bowel Disease
Status: UNKNOWN
Conditions: Fecal Microbiota Transplantation
Interventions: DEVICE: endoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Evaluate the Safety and Efficacy of Candela Technology
Status: RECRUITING
Conditions: Hair Reduction|Tattoo Removal|Wrinkle|Acne|Scars|Benign Cutaneous Vascular Lesions|Skin Conditions
Interventions: DEVICE: Nordlys, Gentle, Picoway, Vbeam, Profound, Profound Matrix, eTwo, Exceed, CO2RE
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Sacral Erector Spinae Plane Block Effect on Post-Hemorrhoidectomy Pain
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: PROCEDURE: Sacral Erector Spinae Plane Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Adapting a Behavioral Intervention to Accommodate Cognitive Dysfunction in People Who Inject Drugs
Status: COMPLETED
Conditions: Cognitive Dysfunction
Interventions: BEHAVIORAL: standard Community-Friendly Health Recovery Program- Biobehavioral (CHRP-BB)|BEHAVIORAL: enhanced Community-Friendly Health Recovery Program- Biobehavioral (CHRP-BB)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Complementary Therapy in Home Palliative Care Patients and Their Caregivers
Status: UNKNOWN
Conditions: Music Therapy|Caregivers|Palliative Care
Interventions: OTHER: Music Therapy|OTHER: simulation with therapeutic education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Rosiglitazone Maleate in Treating Patients With Oral Leukoplakia
Status: COMPLETED
Conditions: Oral Leukoplakia
Interventions: DRUG: rosiglitazone maleate|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Multicenter Comparison of Fluconazole (UK-49,858) and Amphotericin B as Maintenance Treatment for the Prevention of Relapse of Cryptococcal Meningitis in Patients With Acquired Immunodeficiency Syndrome
Status: COMPLETED
Conditions: Meningitis, Cryptococcal|HIV Infections
Interventions: DRUG: Fluconazole|DRUG: Amphotericin B
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Thumbtack Needle in the Treatment of NVP
Status: NOT_YET_RECRUITING
Conditions: Nausea and Vomiting in Pregnancy (NVP)
Interventions: DEVICE: thumbtack needle|DEVICE: sham thumbtack needle|OTHER: black control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Cidofovir for Recurrent Respiratory Papillomatosis
Status: COMPLETED
Conditions: Recurrent Respiratory Papillomatosis
Interventions: DRUG: Cidofovir|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Fluoxetine as a Quit Smoking Aid for Depression-Prone Smokers
Status: COMPLETED
Conditions: Depression|Smoking
Interventions: DRUG: Fluoxetine|BEHAVIORAL: Behavioral group smoking cessation treatment|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Investigating the Effects of Osteopathic Manipulative Treatment on Stress Management in Medical Students
Status: COMPLETED
Conditions: Stress, Job|Student Burnout|Stress, Physiological|Stress, Psychological
Interventions: OTHER: Osteopathic Manipulative Medicine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: To Estimate the Potential Effects of Repeat Doses of Darapladib on the Pharmacokinetics (PK) of Rosuvastatin as Well as Evaluating Safety and Tolerability in Healthy Volunteers
Status: COMPLETED
Conditions: Atherosclerosis
Interventions: DRUG: Rosuvastatin 10 mg|DRUG: Darapladib 160 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Head and Neck Registry of the European Reference Network on Rare Adult Solid Cancers
Status: RECRUITING
Conditions: Head and Neck Cancer|Nasopharynx Cancer|Nasal Cavity and Paranasal Sinus Cancer|Salivary Gland Cancer|Middle Ear Carcinoma
Interventions: OTHER: observation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pharmacodynamic-pharmacokinetic Trial, of Slow Release ASA, in the Platelet Functionalism.
Status: COMPLETED
Conditions: Cardiovascular Disease
Interventions: DRUG: slow release acetyl salicylic acid|DRUG: ASA|DRUG: SR-ASA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Phase 1 Open-label Study of TRX518 Monotherapy and TRX518 in Combination With Gemcitabine, Pembrolizumab, or Nivolumab
Status: COMPLETED
Conditions: Solid Tumors
Interventions: DRUG: TRX518 monotherapy|DRUG: TRX518 with gemcitabine|DRUG: TRX518 with pembrolizumab|DRUG: TRX518 with nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Investigating the Safety, Absorption, and Elimination of MB04, a New Compound That May Potentially be Used in the Treatment of Autoimmune Disorders
Status: RECRUITING
Conditions: Healthy Volunteers
Interventions: DRUG: MB04|DRUG: US License Enbrel|DRUG: EU Source Enbrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Study of Bilateral Upper Laryngeal Nerve Block for Supporting the Removal of Vocal Cord Polyps Under Laryngoscopy
Status: UNKNOWN
Conditions: Vocal Cord Polyp
Interventions: PROCEDURE: USG-guided iSLN block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Biomarkers in Predicting Treatment Response in Samples From Patients With Early-Stage Non-Small Cell Lung Cancer Previously Treated With Adjuvant Chemotherapy
Status: NOT_YET_RECRUITING
Conditions: Stage IA Non-small Cell Lung Cancer|Stage IB Non-small Cell Lung Cancer|Stage IIA Non-small Cell Lung Cancer|Stage IIB Non-small Cell Lung Cancer|Stage IIIA Non-small Cell Lung Cancer
Interventions: OTHER: medical chart review|OTHER: laboratory biomarker analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Fractional Flow Reserve Versus Angiography for Multivessel Evaluation (F.A.M.E.)
Status: COMPLETED
Conditions: Coronary Arteriosclerosis
Interventions: DEVICE: Fractional flow reserve|PROCEDURE: Angio-guided PCI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Orthostatic Hypotension Treatment on Rehab Unit
Status: COMPLETED
Conditions: Orthostatic Hypotension|Falls
Interventions: OTHER: Medication review|OTHER: Nutrition/Salt intake|OTHER: Education|OTHER: Exercise|OTHER: Drug Recommendations
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Relationship Between the Activity of Rheumatoid Arthritis and Lymph Node Morphology and Lymphatics Drainage
Status: UNKNOWN
Conditions: Rheumatoid Arthritis|Lymph Node Mass|Lymphatic Vessel; Dilatation
Interventions: DRUG: indocyanine green(ICG)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Evaluate the Safety, Pharmacokinetics, and Activity of GDC-6036 Alone or in Combination in Participants With Advanced or Metastatic Solid Tumors With a KRAS G12C Mutation
Status: RECRUITING
Conditions: Non-Small Cell Lung Cancer|Colorectal Cancer|Advanced Solid Tumors
Interventions: DRUG: GDC-6036|DRUG: Atezolizumab|DRUG: Cetuximab|DRUG: Bevacizumab|DRUG: Erlotinib|DRUG: GDC-1971|DRUG: Inavolisib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Furosemide 40 mg Tablet in 24 Indonesian Healthy Volunteers
Status: COMPLETED
Conditions: Drug Use
Interventions: DRUG: Furosemide 40 mg|DRUG: Lasix® 40 mg Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety and Effectiveness of PRI-724 for Hepatitis C or B Virus Derived Liver Cirrhosis
Status: COMPLETED
Conditions: Hepatitis C|Hepatitis B|Liver Cirrhoses
Interventions: DRUG: PRI-724
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Ahmed Glaucoma Valve FP7 and FP8 in Pediatric Glaucoma
Status: UNKNOWN
Conditions: Pediatric Glaucoma
Interventions: DEVICE: FP7 Ahmed Glaucoma Drainage Implant|DEVICE: FP8 Glaucoma Drainage Implant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Postoperative Belladonna and Morphine Suppositories in Vaginal Surgery
Status: COMPLETED
Conditions: Vaginal Surgery
Interventions: DRUG: Belladonna and Opium Suppositories|DRUG: Placebo Suppositories
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Influence of Sodium Bicarbonate on Time-to-exhaustion at Critical Power in Endurance Athletes
Status: COMPLETED
Conditions: Performance
Interventions: DIETARY_SUPPLEMENT: Sodium bicarbonate|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Thermomechanical Distraction and Social Anesthesia in Interventional Radiology to Improve Patient Satisfaction
Status: UNKNOWN
Conditions: Pain|Analgesia|Anxiety
Interventions: DEVICE: Buzzy thermomechanical device|BEHAVIORAL: Music Selection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of a Single Dose of NA-1 in Patients Undergoing Endovascular Repair of Ruptured Aneurysms
Status: WITHDRAWN
Conditions: Subarachnoid Hemorrhage|Ruptured Intracranial Aneurysm
Interventions: DRUG: NA-1|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: VACcination In Methotrexate Treated Rheumatoid Arthritis Patients
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: BIOLOGICAL: Prevenar 13|BIOLOGICAL: Pneumo23 / Pneumovax|DRUG: Methotrexate - Immediate|DRUG: Methotrexate - Delay
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anti-peristaltic Ileo-sigmoid Anastomosis for the Treatment of Slow-transit Constipation:Therapeutic Evaluation
Status: COMPLETED
Conditions: Constipation
Interventions: PROCEDURE: Anti-peristaltic ileosigmoid anastomosis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Antiplatelet Therapy After Cardiac Arrest
Status: COMPLETED
Conditions: Cardiac Arrest|Postresuscitation Syndrome|Myocardial Infarction (ST-Elevation Myocardial Infarction and Non-ST-Elevation Myocardial Infarction)
Interventions: DRUG: Clopidogrel|DRUG: Ticagrelor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Magnetic Tape Over Hip Flexion in Patients With Low Back Pain.
Status: WITHDRAWN
Conditions: Low Back Pain
Interventions: DEVICE: Magnetic Tape|DEVICE: Kinesiology Tape
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Flumazenil on Recovery After Total Intravenous Anesthesia With Remimazolam
Status: RECRUITING
Conditions: Flumazenil Adverse Reaction|Remimazolam|Hip Joint|Elderly Patients
Interventions: DRUG: Flumazenil|DRUG: normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Inspiratory Muscle Training in Postmenopausal Women
Status: RECRUITING
Conditions: Postmenopausal Symptoms|Aging|Obesity
Interventions: DEVICE: PrO2 Fit (IMT Trainer)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Uro-DNA Collection for Expanded Genome-Wide Association Study (GWAS) of Renal Cell Carcinoma (RCC)
Status: COMPLETED
Conditions: Kidney Cancer
Interventions: PROCEDURE: Intervention in the UroCCR sites|PROCEDURE: Intervention in the CRB of Bordeaux University Hospital|PROCEDURE: Intervention at the Methodology and Data Management Centre of Bordeaux University Hospital|PROCEDURE: Subsequent intervention at the NCI (for information)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical Outcome and Cytokine Expression After TKA
Status: ACTIVE_NOT_RECRUITING
Conditions: Osteoarthritis
Interventions: DEVICE: Coated Total Knee Arthroplasty|DEVICE: Standard Total Knee Arthroplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: DECIFER: Depression and Citalopram In First Episode Recovery
Status: COMPLETED
Conditions: Schizophrenia|Schizophreniform Disorder
Interventions: DRUG: Citalopram|DRUG: Placebo|BEHAVIORAL: Psychoeducation|BEHAVIORAL: Cognitive Behavioral Therapy (CBT)|RADIATION: Functional Magnetic Resonance Imaging (fMRI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Evaluate the Possible Efficacy and Safety of Febuxostat in Patients With Ulcerative Colitis Treated With Mesalamine
Status: NOT_YET_RECRUITING
Conditions: Ulcerative Colitis
Interventions: DRUG: Febuxostat|DRUG: Mesalamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Improving the Efficacy of Experimental Malaria Vaccine AMA1-C1/Alhydrogel® (Registered Trademark)
Status: COMPLETED
Conditions: Healthy Volunteer|HV
Interventions: DRUG: AMA1-C1/Alhydrogel + CpG 7909
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Bronchoscopic Closure of Bronchopleural Fistulas With Occlutech Figulla ASD N Occluder Device
Status: COMPLETED
Conditions: Bronchopleural Fistula
Interventions: DEVICE: Closure of bronchopleural fistula with Occlutech Figulla
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Prulifloxacin Versus Placebo in Traveler's Diarrhea
Status: COMPLETED
Conditions: Acute Gastroenteritis in Adult Travelers
Interventions: DRUG: Prulifloxacin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Research In Viral Eradication of HIV Reservoirs
Status: COMPLETED
Conditions: HIV
Interventions: DRUG: Combination Antiretroviral Therapy (cART)|DRUG: Raltegravir|DRUG: Vorinostat|BIOLOGICAL: ChAdV63.HIVconsv (ChAd)|BIOLOGICAL: MVA.HIVconsv (MVA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasound-Guided Erector Spinae Plane Block Following Upper Extremity Surgery
Status: WITHDRAWN
Conditions: Upper Extremity Problem
Interventions: OTHER: Erector spinae plane block (Group E)|OTHER: Sham block group (Group S)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treating Patients With Aneurysmal SubArachnoid Hemorrhage (SAH) With Epoetin Alfa
Status: TERMINATED
Conditions: Subarachnoid Hemorrhage
Interventions: DRUG: Epoetin alfa|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Two Forms of Pentamidine in HIV-Infected Children Who May Have Pneumocystis Carinii Pneumonia
Status: COMPLETED
Conditions: Pneumonia, Pneumocystis Carinii|HIV Infections
Interventions: DRUG: Pentamidine isethionate
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Exercise on Physical Function in Older Women With Osteoporosis and a History of Vertebral Fracture
Status: COMPLETED
Conditions: Osteoporosis|Vertebral Fractures
Interventions: OTHER: Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ruxolitinib in Combination With Autotransplant
Status: WITHDRAWN
Conditions: Myelofibrosis|MF
Interventions: DRUG: RUXOLITINIB / INC 424|DRUG: Filgrastim|DRUG: Busulfan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Integrated Pulmonary Index and Opioid Based Patient Controlled Analgesia
Status: COMPLETED
Conditions: Brain Tumors
Interventions: DRUG: Morphine PCA 1 mg|DRUG: Morphine PCA 0,5 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cognitive Deficits in Major Depressive Disorder and Bipolar Disorder, Depressed Type: Prevalence and Improvement With Treatment of Depressive Symptoms
Status: COMPLETED
Conditions: Major Depression|Bipolar Disorder
Interventions: OTHER: Prevalence
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: GEN1047 for Solid Tumors - First in Human (FIH) Trial
Status: RECRUITING
Conditions: Breast Cancer, Breast Neoplasms|Endometrial Cancer, Endometrial Neoplasm|Ovarian Cancer, Ovarian Neoplasms|Squamous Non Small Cell Lung Cancer (NSCLC-SCC)
Interventions: BIOLOGICAL: GEN1047 is a bispecific antibody that induces T-cell mediated cytotoxicity of B7H4-positive tumor cells.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficiency of INTERCOAT (Oxiplex/AP Gel) in Preventing Intrauterine Adhesion Formation in Hysteroscopic Surgery
Status: UNKNOWN
Conditions: Asherman Syndrome|Endometrial Polyp|Uterine Myoma
Interventions: DRUG: INTERCOAT administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Intramyocardial Transplantation of Bone Marrow Stem Cells in Addition to Coronary Artery Bypass Graft (CABG) Surgery
Status: TERMINATED
Conditions: Myocardial Ischemia|Coronary Artery Disease
Interventions: DRUG: CD133+ autologous bone marrow stem cell|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study of SBRT With Adjuvant Pazopanib for Renal Cell Cancer
Status: WITHDRAWN
Conditions: Clear Cell Renal Cell Carcinoma|Renal Cell Carcinoma
Interventions: RADIATION: Stereotactic Radiosurgery|DRUG: Pazopanib Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness Comparison of Thoracic Thrust Manipulation in People With Neck or Low Back Pain
Status: COMPLETED
Conditions: Neck Pain|Low Back Pain
Interventions: OTHER: Massage and stretching on neck area and thoracic thrust manipulation|OTHER: Massage and stretching on low back area and thoracic thrust manipulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Internet-delivered Cystic Fibrosis Mental Health Prevention, Wellness, Resource Program: How Does it Work?
Status: NOT_YET_RECRUITING
Conditions: Cystic Fibrosis in Children|Siblings|Mental Health|Internet-based Intervention
Interventions: BEHAVIORAL: Internet-delivered Cystic Fibrosis Mental Health Prevention, Wellness, and Resource (iCF-PWR) program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Lumbar Degenerative Disc Disease Treatment With Bone Marrow Autologous Mesenchymal Stem Cells (MSV)
Status: WITHDRAWN
Conditions: Degenerative Disc Disease
Interventions: OTHER: Autologous bone marrow mesenchymal stem cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating a Collaborative Care Model for the Treatment of Schizophrenia (EQUIP)
Status: COMPLETED
Conditions: Schizophrenia Disorders|Chronic Illness|Schizoaffective Disorder|Weight Gain
Interventions: PROCEDURE: Collaborative Chronic Illness Model
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Serial EValuation of multiplE Coronary Artery Diseases by an Optical Coherence Tomography; Assessment of the Changes of de Novo Lesions and Comparisons of Neointimal Coverage Between Xience Prime® Versus Cypher SelectTM Stents; SEVEN-Xience Study
Status: COMPLETED
Conditions: Multi-vessel Diseases, Angina
Interventions: DEVICE: Sirolimus-eluting stent (Cypher SelectTM, Cordis, Miami, FL)|DEVICE: Everolimus-eluting stent(Xience Prime®, Abbott Vascular, Santa Claea, CA)|DRUG: Pravastatin 20mg|DRUG: Atorvastatin 40mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Modified Post-Anesthetic Discharge Scoring System (PADSS) Between 4 and 24 Hours in Patients Undergoing Laparoscopic Cholecystectomy
Status: RECRUITING
Conditions: Laparoscopic Cholecystectomy
Interventions: OTHER: Modified Post-Anesthetic Discharge Scoring System (PADSS) between 4 and 24 hours|PROCEDURE: Laparoscopic Cholecystectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Reinitiation of Anticoagulation After Temporary Withdrawal of Vitamin K Antagonist
Status: COMPLETED
Conditions: Atrial Fibrillation|Venous Thromboembolism|Heart Valve Disease|Surgery
Interventions: DRUG: Double dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Protein-bound Versus Free Amino Acid Nutrition During INtestinal Malabsorption in Critical Illness
Status: COMPLETED
Conditions: Intestinal Malabsorption|Critical Illness|Protein Malnutrition
Interventions: DIETARY_SUPPLEMENT: Milk protein (food grade protein)|DIETARY_SUPPLEMENT: Fee amino acids (food grade amino acids)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Trial of Aflibercept Monotherapy With DCE-US in Chemorefractory Metastatic Colorectal Cancer
Status: WITHDRAWN
Conditions: Colorectal Cancer
Interventions: DRUG: Aflibercept|PROCEDURE: Dynamic Contrast Enhanced Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ESPRIT I: A Clinical Evaluation of the Abbott Vascular ESPRIT BVS (Bioresorbable Vascular Scaffold) System
Status: COMPLETED
Conditions: Atherosclerosis|Peripheral Vascular Disease|Claudication
Interventions: DEVICE: ESPRIT BVS
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT