pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Feasibility of Four-dimensional Hysterosalpingo-contrast Sonography With SonoVue for Assessment of Tubal Patency
Status: UNKNOWN
Conditions: Four Dimensional Hysterosalpingo-contrast Sonography|Tubal Patency
Interventions: DEVICE: four dimensional hysterosalpingo-contrast sonography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of the Efficacy of Levofloxacin-based Sequential Therapy and Triple Therapy as Second Line Therapy
Status: UNKNOWN
Conditions: Eradication Rate for Helicobacter
Interventions: DRUG: levofloxacin-based sequential therapy|DRUG: levofloxacin-based triple therapy for 10 days
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Study Between Suction Aspiration and Combination Technique in Acute Cerebral Infarction
Status: ENROLLING_BY_INVITATION
Conditions: Acute Cerebral Ischemia Requiring for Mechanical Thrombectomy
Interventions: DEVICE: mechanical thrombectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Registry To Evaluate Safety And Effectiveness Of Everolimus Drug Eluting Stent For Coronary Revascularization
Status: UNKNOWN
Conditions: Coronary Artery Diseases
Interventions: PROCEDURE: Everolimus Drug Eluting Stent|DRUG: Aspirin|DRUG: Clopidogrel|DRUG: Heparin or Bivalirudin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Sequential Stent Addition vs. Incremental Dilation & Stent Exchange for Management of Anastomotic Biliary Strictures After Liver Transplantation
Status: UNKNOWN
Conditions: Anastomotic Stenosis|Biliary Stricture
Interventions: PROCEDURE: Protocol for increasing number of stents across the anastomosis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Extension Study of MT-1303
Status: COMPLETED
Conditions: Relapsing-remitting Multiple Sclerosis
Interventions: DRUG: MT-1303-Low|DRUG: MT-1303-Middle|DRUG: MT-1303-High
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Thiazolidinediones on Human Bone
Status: COMPLETED
Conditions: Osteoblast|Adipocytes|Bone Density|Osteocalcin|Adiponectin|Mesenchymal Stem Cells
Interventions: DRUG: Pioglitazone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Chemotherapy and Radiation Therapy Before Surgery Followed by Capecitabine With or Without Oxaliplatin in Treating Patients With Locally Advanced Rectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: capecitabine|DRUG: oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Investigation of Psilocybin on Behavioural and Cognitive Symptoms of Adults With Fragile X Syndrome
Status: SUSPENDED
Conditions: Fragile X Syndrome|Behavior|Cognitive Dysfunction
Interventions: DRUG: Psilocybin, 1.5 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cefepime vs Ceftazidime as Empirical Therapy for Neutropenic Fever
Status: COMPLETED
Conditions: Neutropenia, Febrile|Leukemia|Pediatric Cancer|Antibiotic Reaction
Interventions: DRUG: Ceftazidime Injection|DRUG: Cefepime Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects and Safety of Diabetic GUideline Algorithm Implementation Performed by Primary Care Physicians in the Community
Status: RECRUITING
Conditions: Type 2 Diabetes|Cardiovascular Complication|Diabetic Kidney Disease
Interventions: OTHER: Intensive guideline algorithm implementation|OTHER: Conventional guideline algorithm implementation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effect of the OMT Exercises Education for Pain in Participants With Cervical Pain
Status: COMPLETED
Conditions: Neck Pain|Pain, Neck
Interventions: PROCEDURE: Exercises and PNE|PROCEDURE: Osteopathic manipulative treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transhepatic Echography for Fluid Responsiveness After Cardiovascular Surgery
Status: UNKNOWN
Conditions: Inferior Vena Cava Abnormality|Fluid Responsiveness|Fluid Overload|Venous Congestion|Cardiovascular Surgery
Interventions: DIAGNOSTIC_TEST: Echocardiography and transhepatic inferior vena cava assessment using ultrasound.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Leveraging Autism Intervention for Families Using Telehealth (LIFT)
Status: NOT_YET_RECRUITING
Conditions: Autism Spectrum Disorder
Interventions: BEHAVIORAL: ONLINE|BEHAVIORAL: COACH
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of C-PRF vs i-PRF in Thin Gingival Biotype Subjects
Status: COMPLETED
Conditions: Thin Gingival Biotype
Interventions: OTHER: Platelets Rich Fibrin (i-PRF / C-PRF)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigational and Comparative Study in the Management of Diabetic Nephropathy
Status: COMPLETED
Conditions: Diabetic Nephropathy Type 2
Interventions: DRUG: Tadalafil 20Mg Oral Tablet|DRUG: Pentoxifylline 400 MG Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of 10-day and 14-day Bismuth-based Quadruple Therapy in First-line H. Pylori Eradication
Status: ENROLLING_BY_INVITATION
Conditions: Helicobacter Pylori Infection|Dysbiosis|Probiotics
Interventions: DRUG: Bismuth Subcitrate 120 MG Oral Tablet|DIETARY_SUPPLEMENT: Lactobacillus acidophilus and Bifidobacterium lactis Bb12|DRUG: Esomeprazole 40mg|DRUG: Metronidazole 250 MG|DRUG: Tetracycline Pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess Repeated Doses of INDV-2000 in Healthy Volunteers and in Treatment Seeking Individuals With Opioid Use Disorder
Status: COMPLETED
Conditions: Healthy Volunteer|Opioid-use Disorder
Interventions: DRUG: INDV-2000|DRUG: Placebo|DRUG: SUBOXONE® sublingual film
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Omission of Pumice Prophylaxis on Bracket Failure Rates Using Self Etch Primers
Status: UNKNOWN
Conditions: Orthodontic Appliance Complication
Interventions: OTHER: Pumice prophylaxis|OTHER: No pumice prophylaxis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Head and Neck Maskless Immobilization Device in Immobilizing Patients With Head and Neck Cancer or Intracranial Tumors Undergoing Radiation Therapy
Status: COMPLETED
Conditions: Brain and Nervous System|Intracranial Neoplasm|Head and Neck Cancer
Interventions: PROCEDURE: Computed Tomography|DEVICE: Medical Device|DEVICE: Medical Device|PROCEDURE: Cone-Beam Computed Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Gabapentin to Reduce Alcohol and Improve Viral Load Suppression
Status: RECRUITING
Conditions: HIV|Heavy Drinking
Interventions: DRUG: Gabapentin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Tisporin Eye Drops Group and Restasis Eye Drops Group After Treatment, Each Treatment Group Comparisons for Evaluation of Efficacy and Safety in Moderate to Severe Dry Eye Disease
Status: COMPLETED
Conditions: Dry Eye Syndromes
Interventions: DRUG: Cyclosporine ophthalmic solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Smoking Cessation Treatment for Head & Neck Cancer Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Head and Neck Cancer|Smoking Cessation
Interventions: BEHAVIORAL: Acceptance and Commitment Therapy|BEHAVIORAL: Motivational and Behavioral Counseling|DRUG: Varenicline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating the Safety, Tolerability and Pharmacokinetics of Desvenlafaxine Succinate SR in Healthy Chinese Male and Females
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: desvenlafaxine succinate SR|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Yoga for Managing Knee Osteoarthritis in Older Women: a Feasibility Study
Status: COMPLETED
Conditions: Osteoarthritis, Knee|Quality of Life|Poor Quality Sleep|Physical Impairment
Interventions: BEHAVIORAL: Hatha yoga|BEHAVIORAL: Hatha Yoga
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: LiveSMART Trial to Prevent Falls in Patients With Cirrhosis
Status: RECRUITING
Conditions: Cirrhosis, Liver|Portal Hypertension
Interventions: BEHAVIORAL: Enhanced Usual Care|DRUG: Lactulose|BEHAVIORAL: Investigator recommended exercise|BEHAVIORAL: TeleTai-Chi (virtual)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ADIRA (Anti-inflammatory Diet In Rheumatoid Arthritis)
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: OTHER: Fiber diet|OTHER: Protein diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Botulinum Toxin A Versus Steroids for the Treatment of Chronic Plantar Fasciitis
Status: RECRUITING
Conditions: Plantar Fasciitis
Interventions: DRUG: Botulinum toxin A|DRUG: cortisone|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessing Superion Clinical Endpoints vs. Decompression
Status: WITHDRAWN
Conditions: Spinal Stenosis, Lumbar Region With Neurogenic Claudication
Interventions: DEVICE: Superion® IDS|PROCEDURE: Direct decompression Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Black Raspberry Phytochemicals on Oral Microbiome in Current Smokers and Non-smokers
Status: COMPLETED
Conditions: Healthy Subject|Tobacco Use Disorder
Interventions: OTHER: Laboratory Biomarker Analysis|DIETARY_SUPPLEMENT: Phytochemical|OTHER: Placebo|OTHER: Screening Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: iSONEP to Treat Persistent Pigment Epithelial Detachment (PED) in Subjects With Exudative Age-Related Macular Degeneration (AMD) or Polypoidal Choroidal Vasculopathy (PCV)
Status: TERMINATED
Conditions: Pigment Epithelial Detachment
Interventions: DRUG: iSONEP (sonepcizumab/LT1009)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Performance Evaluation of a Biological Matrix Used for Rectal Prolapse Repair by Ventral Rectopexy
Status: COMPLETED
Conditions: Rectal Prolapse
Interventions: DEVICE: CELLIS Rectopexy (Porcine Acellular Dermal Matrix, PADM)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Sevoflurane- Safety in Long-term Sedation Procedures
Status: WITHDRAWN
Conditions: Poisoning by Inhaled Anaesthetic|Fluoride Poisoning|Recovery From Sedation|Renal Function|Hepatic Function
Interventions: DRUG: Sevoflurane|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Tobramycin-Dexamethasone Versus Tobramycin-Dexamethasone Plus Ketorolac After Phacoemulsification Surgery
Status: COMPLETED
Conditions: Cataract
Interventions: DRUG: Tobramycin 0.3% - Dexamethasone 0.1%|DRUG: Tobramycin 0.3% - Dexamethasone 0.1% plus Ketorolac tromethamine 0.5%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Alternative Healthy Eating Index-Based Diet on Inflammatory Markers and Breast Density in Healthy Participants
Status: COMPLETED
Conditions: Healthy Subject
Interventions: DIETARY_SUPPLEMENT: Dietary Intervention|PROCEDURE: Dual X-ray Absorptiometry|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Reduce Pain and Improve Quality of Life in Patient With Knee Osteoarthritis by Light, Sound and Brain Stimulation
Status: UNKNOWN
Conditions: Knee Osteoarthritis
Interventions: OTHER: High Intensity LASER Therapy (HILT)|OTHER: Ibuprofen Gel Phonophoresis (IGP)|OTHER: Transcranial Direct Current Stimulation (tDCS)|OTHER: Conventional Physiotherapy (CPT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cadonilimab (AK104) Combined With Chemotherapy and Bevacizumab as First-line Treatment for RAS Mutated or Right Sided-metastatic MSS Colorectal Cancer
Status: RECRUITING
Conditions: Colorectal Cancer
Interventions: DRUG: Cadonilimab (AK104) combined with chemotherapy and bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Video and Macintosh Laryngoscope in Patients Who May be Difficult to Intubate
Status: COMPLETED
Conditions: Intubation, Endotracheal
Interventions: DEVICE: DCI Video Intubation System-Macintosh Laryngoscope|DEVICE: Macintosh Laryngoscope
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose:
Clinical trial: CO2 Insufflation During Single-Balloon-Enteroscopy
Status: COMPLETED
Conditions: Pain
Interventions: DEVICE: Single-Balloon-Enteroscopy with Air as insufflation gas.|DEVICE: Single-Balloon-Enteroscopy with CO2 as insufflation gas.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating Pantoprazole in Children With Gastroesophageal Reflux Disease (GERD)
Status: COMPLETED
Conditions: Gastroesophageal Reflux
Interventions: DRUG: pantoprazole sodium enteric-coated spheroid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Bone Marrow to Prevent Graft-Versus-Host Disease in Patients With Acute or Chronic Leukemia Undergoing Bone Marrow Transplantation
Status: COMPLETED
Conditions: Graft Versus Host Disease|Leukemia|Myelodysplastic Syndromes
Interventions: BIOLOGICAL: anti-thymocyte globulin|BIOLOGICAL: filgrastim|DRUG: cyclophosphamide|DRUG: fludarabine phosphate|DRUG: methylprednisolone|DRUG: tacrolimus|PROCEDURE: allogeneic bone marrow transplantation|PROCEDURE: in vitro-treated bone marrow transplantation|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Research Study to Compare Two Forms of Semaglutide in Two Different Pen-injectors in People With Overweight or Obesity
Status: TERMINATED
Conditions: Overweight|Obesity
Interventions: DRUG: Semaglutide (administered by DV3396 pen)|DRUG: Semaglutide (administered by PDS290 pen)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Different Dosages of Solute Clearance on Outcome in Twice Weekly Hemodialysis Patients
Status: COMPLETED
Conditions: Renal Replacement Therapy|Hemodialysis
Interventions: PROCEDURE: modification of hemodialysis parameters on dialysis machine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The HAPPINESS Trial: cHAnging the Perceived Pain INtensity in divErSe Populations With Spinal Cord Injury
Status: RECRUITING
Conditions: Spinal Cord Injuries
Interventions: BEHAVIORAL: Qigong|BEHAVIORAL: Daily 2 min pain management survey
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Health Effects of Oat and Oat Polar Lipids in Human
Status: COMPLETED
Conditions: Postprandial Glucose Regulation
Interventions: COMBINATION_PRODUCT: Effects of Oat and Oat Components on Cardiometabolic risk variables
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Sex Differences in the Dilatory Response of Compound 21
Status: ACTIVE_NOT_RECRUITING
Conditions: Sex Differences
Interventions: DRUG: Compound 21|DRUG: Compound 21 + losartan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: SWAN: Study on the Tolerance and Efficacy of a New Anti-regurgitation Formula (PC-2016-01)
Status: COMPLETED
Conditions: Gastroesophageal Reflux
Interventions: DIETARY_SUPPLEMENT: Thickened infant formula
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MK0954 Versus Placebo for Treatment of Mild to Moderate Hypertension
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: losartan potassium|DRUG: Comparator: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Orally Administered GB1211 in Participants With Suspected or Confirmed Non-alcoholic Steatohepatitis (NASH) and Liver Fibrosis
Status: WITHDRAWN
Conditions: Non-alcoholic Steatohepatitis (NASH)
Interventions: DRUG: GB1211|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Marginal Bone Loss of Two Immediately Loaded Implants Retaining Mandibular Overdenture
Status: NOT_YET_RECRUITING
Conditions: Edentulous Alveolar Ridge
Interventions: PROCEDURE: implant supported overdenture by ball|PROCEDURE: implant supported overdenture by bar
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Effects of MK0812 on Disease Activity in Patients With Relapsing-Remitting Multiple Sclerosis as Measured by Magnetic Resonance Imaging (MRI)(0812-003)(COMPLETED)
Status: TERMINATED
Conditions: Relapsing-Remitting Multiple Sclerosis
Interventions: DRUG: MK0812
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy Plus Hormone Therapy Versus Androgen Suppression in Treating Patients With Metastatic or Unresectable Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: Bicalutamide|DRUG: Doxorubicin hydrochloride|DRUG: Estramustine Phosphate Sodium|DRUG: Flutamide|DRUG: Ketoconazole|DRUG: Nilutamide|DRUG: Therapeutic Hydrocortisone|DRUG: Vinblastine|PROCEDURE: Conventional Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Expand Access/Assess Safety and Efficacy of Paromomycin IM Injection for the Treatment of Visceral Leishmaniasis
Status: COMPLETED
Conditions: Visceral Leishmaniasis
Interventions: DRUG: Paromomycin sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transcutaneous Electrical Acupoint Stimulation (TEAS) for Chronic Constipation
Status: RECRUITING
Conditions: Constipation - Functional
Interventions: DEVICE: Verum TEAS|DEVICE: Sham TEAS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Moxibustion Therapy With or Without Smoke for Knee Osteoarthritis
Status: COMPLETED
Conditions: Pain
Interventions: OTHER: Moxibustion|OTHER: Moxa smoke purification device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Vitamin D Deficiency and Replacement on Pulmonary and Endocrine Function in SCI
Status: COMPLETED
Conditions: Spinal Cord Injury|Vitamin D Deficiency
Interventions: DRUG: Vitamin D3
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Quadruple Therapy in Eradication of H. Pylori: A Comparison to Triple Therapy
Status: COMPLETED
Conditions: Helicobacter Infections
Interventions: DRUG: Omeprazole, amoxicillin, clarithromycin|DRUG: Pylera (Bismuth subcitrate potassium, metronidazole, tetracycline) given in combination with omeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: "Which Type of Exercise is More Effective in Chronic Constipation?
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Constipation
Interventions: OTHER: Group is doing breathing exercises while watching videos|OTHER: Medium pace walking group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SMART Health Pregnancy 2 - Intervention to Reduce Anaemia and Cardiometabolic Risk During Pregnancy and in the First Year Following Birth
Status: RECRUITING
Conditions: Anemia of Pregnancy|Gestational Diabetes|Gestational Hypertension|Pre-Eclampsia|Anemia|Type 2 Diabetes|Hypertension
Interventions: OTHER: SMARThealth Pregnancy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Cartilage Tympanoplasty for Recurrent Perforation Full Thickness Versus Partial Thickness Graft
Status: UNKNOWN
Conditions: Cartilage Tympanoplasty
Interventions: PROCEDURE: Cartilage tympanoplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Self-efficacy Enhancing Stroke Self-management Program for Community-dwelling Stroke Survivors
Status: COMPLETED
Conditions: Stroke
Interventions: BEHAVIORAL: Stroke self-management program|BEHAVIORAL: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Allogeneic Stem Cell Transplantation for Patients With Multiple Myeloma
Status: WITHDRAWN
Conditions: Multiple Myeloma|Myeloma-Multiple
Interventions: BIOLOGICAL: Tocilizumab|DRUG: Melphalan|DRUG: Fludarabine|DRUG: Cyclophosphamide|DRUG: Tacrolimus|DRUG: Mycophenolate mofetil|DRUG: Filgrastim
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Nivolumab Plus Bempegaldesleukin (Bempeg/NKTR-214) vs Nivolumab Alone vs Standard of Care in Participants With Bladder Cancer That May Have Invaded The Muscle Wall of the Bladder and Who Cannot Get Cisplatin, A Type of Medicine Given To Treat Bladder Cancer
Status: COMPLETED
Conditions: Bladder Cancer|Bladder Tumor|Muscle-Invasive Bladder Cancer
Interventions: BIOLOGICAL: Nivolumab|PROCEDURE: Radical cystectomy (RC)|BIOLOGICAL: Bempegaldesleukin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: IPT and Efficacy of Sulphadoxine/Pyrimethamine and Chlorproguanil/Dapsone in 6-59 Month Old Children With Malaria.
Status: TERMINATED
Conditions: Malaria
Interventions: DRUG: sulphadoxine/pyrimethamine|DRUG: Chlorproguanil/dapsone|DRUG: Sulfadoxine/pyrimethamine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A New Diet for Patients With Autosomal Dominant Polycystic Disease (ADPKD)
Status: COMPLETED
Conditions: Autosomal Dominant Polycystic Kidney Disease
Interventions: OTHER: ADPKD Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effects of Glucagon-Like Peptide-1 Analogs on Sexuality
Status: COMPLETED
Conditions: Sexual Functioning
Interventions: DRUG: Dulaglutide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Extension Study of Long-term Safety and Efficacy of Myozyme for a Single Patient With Pompe Disease Who Were Previously Enrolled in Genzyme Sponsored ERT Studies.
Status: COMPLETED
Conditions: Pompe Disease Late-Onset|Glycogen Storage Disease Type II GSD II
Interventions: BIOLOGICAL: Myozyme
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Venetoclax+Azacytidine+Modified BUCY Conditioning Regimen for Acute Myeloid Leukemia and Myelodysplastic Syndromes Undergoing Allo-HSCT
Status: RECRUITING
Conditions: Allogeneic Hematopoietic Stem Cell Transplantation|Acute Myeloid Leukemia|Myelodysplastic Syndrome
Interventions: DRUG: VEN+AZA+Modified BUCY
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: AVAPS-AE Efficacy Study
Status: COMPLETED
Conditions: Obesity Hypoventilation Syndrome
Interventions: DEVICE: AVAPS-AE Mode of Therapy|DEVICE: Respironics OnmiLab BiPAP S mode|DEVICE: Respironics OmniLab Advanced CPAP mode
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of an Emollient Cream Containing 0.5% Cannabidiol and 1% Hemp Oil in the Hydration and Erythema of the Skin
Status: COMPLETED
Conditions: Cosmetics; Eczema
Interventions: OTHER: Topical moisturizer
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Comparison of Precision in Brackets Position in Two Indirect Bonding Materials
Status: UNKNOWN
Conditions: Orthodontic Appliance Complication|Malocclusion
Interventions: PROCEDURE: Accuracy of indirect bonding of self-ligating brackets made with polyvinylsiloxane transfers|PROCEDURE: Accuracy of indirect bonding of self-ligating brackets made with thermal glue transfers
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Exercise Effects on Adipose Tissue Structure and Function
Status: RECRUITING
Conditions: Obesity|Metabolic Syndrome|Metabolic Disease|Insulin Resistance|Weight Loss|Weight Gain
Interventions: BEHAVIORAL: Exercise|BEHAVIORAL: No exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Sevoflurane and Propofol Anesthesia on Postoperative Delirium
Status: UNKNOWN
Conditions: General Anesthesia|Geriatric Patient
Interventions: DRUG: Propofol|DRUG: Sevoflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Topical CBD Cream for Degenerative Hallux Disorders
Status: TERMINATED
Conditions: Hallux Valgus|Hallux Rigidus
Interventions: DRUG: magnesium-cannabidiolic acid cream|DRUG: Placebo cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study to Assess the Safety, PK and PD of Insulin Injected Via MicronJet or Conventional Needle
Status: COMPLETED
Conditions: Intradermal Injections
Interventions: DEVICE: MicronJet|DEVICE: MicronJet
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Manual Wheelchair Speed, Maneuverability, and Endurance and Community Access
Status: TERMINATED
Conditions: Physical Disability
Interventions: OTHER: Life Space Assessment Scale|OTHER: 6-Minute Push Test|OTHER: Forward Push Test|OTHER: Wheelchair Slalom Test|OTHER: Craig Handicap Assessment and Reporting Technique|OTHER: PART-O|OTHER: GPS Tracking
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: To Develop, Implement and Evaluate the Polio Demonstration Project Comprising of a Community Based Intervention Package for Polio Eradication in Pakistan
Status: UNKNOWN
Conditions: Polio|Polio Sero Conversion|Polio Sero Prevalence|Immunization Coverage
Interventions: BEHAVIORAL: Enhanced Community mobilization|BIOLOGICAL: Combined Oral Polio Vaccine and Inject able Polio Vaccine during SIA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: APG-2575 Monotherapy or in Combination With Lenalidomide/DXMS in Subjects With Relapsed or Refractory Multiple Myeloma
Status: RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: APG-2575|DRUG: Rd
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Compare PK and Safety of Subcutaneous Injection of Ustekinumab and CT-P43 in Healthy Subjects
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: BIOLOGICAL: CT-P43|BIOLOGICAL: EU-approved Stelara|BIOLOGICAL: US-licensed Stelara
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Extension of BPS-MR-PAH-203 in Pulmonary Arterial Hypertension (PAH) Patients
Status: COMPLETED
Conditions: Pulmonary Arterial Hypertension
Interventions: DRUG: Beraprost Sodium Modified Release
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Aqueous Suppression After Ahmed Glaucoma Valve (AGV) Implantation
Status: UNKNOWN
Conditions: Hypertensive Phase
Interventions: DRUG: Timolol-trusopt|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ebola and Marburg Virus Vaccines
Status: COMPLETED
Conditions: Ebola Vaccines|Marburg Virus Disease|Ebola Virus Disease|Marburgvirus|Ebolavirus
Interventions: DRUG: VRC-EBODNA023-00-VP|DRUG: VRC-MARDNA025-00-VP
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Tucidinostat and Nab-paclitaxel in Advanced HR+/HER2- Breast Cancer
Status: RECRUITING
Conditions: HR+/HER2- Breast Cancer
Interventions: DRUG: Tucidinostat|DRUG: nab-paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: OsseoFix™ Spinal Fracture Reduction System in Treating Spinal Compression Fracture
Status: TERMINATED
Conditions: Vertebral Compression Fractures
Interventions: DEVICE: OsseoFix Spinal Fracture Reduction System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant PROSTVAC-VF With or Without Ipilimumab for Prostate Cancer
Status: TERMINATED
Conditions: Prostatic Neoplasms
Interventions: BIOLOGICAL: PROSTVAC V/F|DRUG: Ipilimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antioxidant Use in Diabetes to Reduce Oxidative Stress
Status: TERMINATED
Conditions: Ameliorating Oxidative Stress in Type 1 Diabetes
Interventions: DRUG: N-acetyl cysteine|DIETARY_SUPPLEMENT: omega 6 Fish oil ( PUFA)|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Controlled Trial to Investigate the Efficacy and Safety of Frovatriptan to Prevent Menstrual Migraine
Status: COMPLETED
Conditions: Migraine
Interventions: DRUG: Frovatriptan 2.5mg QD|DRUG: Frovatriptan 2.5 mg BID|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose:
Clinical trial: Efficacy and Safety Study of Lipid-Lowering Effects of XueZhiKang (XZK) in Patients With Hyperlipidemia
Status: COMPLETED
Conditions: Hyperlipidemia
Interventions: DRUG: XueZhiKang (XZK), a botanic product with multiple components|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: In-exsufflator Cough Assist Device in Patients With Symptomatic Bronchiectasis
Status: TERMINATED
Conditions: Bronchiectasis
Interventions: DEVICE: In-Exsufflator Cough Assist Device|DEVICE: Active Comparator: Flutter Valve Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Goal-directed and Liberal Fluid Management
Status: WITHDRAWN
Conditions: Goal-Directed Fluid Therapy|Hemodynamic Monitoring|Fluid Management
Interventions: OTHER: Goal-directed fluid treatment|OTHER: Liberal Fluid Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Long-Acting Injectable Risperidone in the Treatment of Schizophrenia
Status: COMPLETED
Conditions: Schizoaffective Disorder|Schizophrenia
Interventions: DRUG: IM risperidone|DRUG: oral antipsychotic medication
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Minimally Invasive Endoscopic Treatment of Zenker's Diverticulum Comparing LigaSureTM vs SB-Knife.
Status: RECRUITING
Conditions: Zenker Diverticulum|Minimally Invasive Surgical Procedures|Endoscopy
Interventions: DEVICE: septotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Development and Research of an Individualized Intelligent Platform for Rehabilitaion in Parkinson's Disease
Status: UNKNOWN
Conditions: Parkinson Disease
Interventions: OTHER: LSVT-BIG|OTHER: POWER|OTHER: Traditional rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Abemaciclib in Participants With Varying Degrees of Liver Impairment
Status: COMPLETED
Conditions: Hepatic Insufficiency
Interventions: DRUG: Abemaciclib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Clomiphene Citrate Plus Gonadotropins and GnRH Antagonist Versus Flexible GnRH Antagonist Protocol Versus Microdose GnRH Agonist Protocol in Poor Responders Undergoing IVF
Status: UNKNOWN
Conditions: Poor Responders|IVF|Clomiphene Citrate|GnRH Agonist|GnRH Antagonist
Interventions: DRUG: Clomiphene citrate|DRUG: Daily FSH and LH plus Cetrorelix|DRUG: Triptorelin plus daily FSH anh LH
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study of Cabozantinib With Lu-177 in Patients With Somatostatin Receptor 2 Positive Neuroendocrine Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Neuroendocrine Tumors
Interventions: DRUG: Cabozantinib|DRUG: Lu-177
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial of a Peptide-based Group A Streptococcal (GAS) Vaccine Candidate in Healthy Individuals.
Status: RECRUITING
Conditions: Group A Streptococcal Infection
Interventions: BIOLOGICAL: p*17-K4S2|BIOLOGICAL: J8-K4S2|BIOLOGICAL: Rabavert vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: CABG Combined Pedicled Omentum Wrapped Autologous Atrial Tissue Patch Cardiomyoplasty for Ischemic Cardiomyopathy
Status: UNKNOWN
Conditions: Ischemic Cardiomyopathy|Congestive Heart Failure|Coronary Artery Disease
Interventions: PROCEDURE: CABG combined cardiomyoplasty|PROCEDURE: CABG combined pedicled omentum graft|PROCEDURE: CABG alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Spanish Atrial Fibrillation And Resynchronization Study
Status: COMPLETED
Conditions: Chronic Heart Failure|Cardiomyopathy, Dilated|Atrial Fibrillation
Interventions: PROCEDURE: Atrio ventricular junction ablation with radio-frequency|DRUG: Beta blocker/digoxine/amiodarone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Targeting the ERN Computerized Intervention Targeting the Error-related Negativity in Young Children
Status: ACTIVE_NOT_RECRUITING
Conditions: Anxiety
Interventions: BEHAVIORAL: Psycho-social, computerized intervention targeting error sensitivity
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of Macitentan in Patients With PAH to Psychometrically Validate PAH-SYMPACT Instrument
Status: TERMINATED
Conditions: Pulmonary Arterial Hypertension
Interventions: DRUG: Macitentan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rituximab and CVP Plus Interferon for Follicular Non Hodgkins Lymphoma (NHL)
Status: COMPLETED
Conditions: Non-Hodgkin's Lymphoma
Interventions: BIOLOGICAL: R+CVP+IFN
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study on Efficacy and Safety of LNP023 in C3 Glomerulopathy Patients Transplanted and Not Transplanted
Status: COMPLETED
Conditions: Glomerulonephritis
Interventions: DRUG: LNP023
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lignocaine Only Versus Lignocaine Plus Magnesium Sulphate for Pain Relief After Episiotomy.
Status: UNKNOWN
Conditions: Episiotomy Wound|Pain, Procedural
Interventions: DRUG: Magnesium sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Outcomes From Remediation and Behavioural Intervention Techniques
Status: RECRUITING
Conditions: Schizophrenia|Psychosis|Psychotic Disorders|Schizophrenia; Psychosis
Interventions: BEHAVIORAL: Cognitive Behavioural Therapy for Psychosis (CBTp)|BEHAVIORAL: Cognitive Remediation Therapy (CR)|BEHAVIORAL: Befriending|BEHAVIORAL: Sham Cognitive Remediation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SB705498 Proof of Concept Chamber Challenge in Subjects With Non Allergic Rhinitis
Status: COMPLETED
Conditions: Rhinitis
Interventions: DRUG: SB-705498|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Partial Breast Versus Whole Breast Irradiation in Elderly Women Operated on for Early Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Carcinoma
Interventions: RADIATION: Partial breast irradiation|RADIATION: Whole breast irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A RCT of Prednisone as Adjunctive Therapy for Hospitalized Patients With Pulmonary TB and HIV Co-infection
Status: WITHDRAWN
Conditions: Tuberculosis|HIV Infections
Interventions: DRUG: Prednisone|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Candesartan on Reducing Blood Pressure in Insulin-Resistant, Obese Patients With Hypertension.
Status: COMPLETED
Conditions: Obesity|Hypertension
Interventions: DRUG: Candesartan and Hydrochlorothiazide|DRUG: Hydrochlorothiazide (HCT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Probiotics Effect on Glucose and Lipid Metabolism and Gut Microbiota in Patients With Type 2 Diabetes
Status: UNKNOWN
Conditions: Diabetes Mellitus, Type 2
Interventions: DIETARY_SUPPLEMENT: probiotics|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Double-blind Placebo-controlled Trial of Generic Clindamycin/Benzoyl Peroxide Gel Versus Onexton Gel in Acne Vulgaris
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: Onexton|DRUG: Clindamycin/benzoyl peroxide gel|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Sofosbuvir Plus Ribavirin in Treatment-Naive Adults With Chronic Genotype 1 or 3 HCV Infection
Status: COMPLETED
Conditions: Chronic HCV Infection
Interventions: DRUG: Sofosbuvir|DRUG: RBV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Pharmacokinetics, Pharmacodynamic Effects, Safety and Tolerability of Repeated Dosing of RO5459072 in Volunteers With Celiac Disease
Status: COMPLETED
Conditions: Celiac Disease
Interventions: DRUG: Placebo|DRUG: RO5459072
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Pharmacokinetic Study of Subcutaneous and Intravenous Rituximab in Participants With Follicular Lymphoma
Status: COMPLETED
Conditions: Lymphoma, Follicular
Interventions: DRUG: Rituximab|DRUG: Rituximab|DRUG: Rituximab|DRUG: Rituximab|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare Nivolumab Drug Product Process D to Nivolumab Drug Product Process C in Participants With Stage IIIa/b/c/d or Stage IV Melanoma After Complete Resection
Status: COMPLETED
Conditions: Melanoma
Interventions: DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Analgesia for Thyroidectomy Using Bilateral Superficial Cervical Plexus Block With Bupivacaine Only or Adding Ketorolac to it.
Status: COMPLETED
Conditions: Thyroid Goiter|Thyroid Nodule
Interventions: DRUG: Bupivacain|DRUG: Ketorolac
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Hetrombopag for the Treatment of Chemotherapy-Induced Thrombocytopenia in Adults With Solid Tumors.
Status: NOT_YET_RECRUITING
Conditions: Chemotherapy-Induced Thrombocytopenia
Interventions: DRUG: Hetrombopag|DRUG: Hetrombopag plus Placebo|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT