pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: RAdiation Dose In percutAneuos Coronary Procedures Through TransradIal apprOach Using Dedicated radiatioN Shields
Status: COMPLETED
Conditions: Myocardial Ischemia
Interventions: PROCEDURE: Coronary angiography|PROCEDURE: PCI|PROCEDURE: Right approach|PROCEDURE: Left approach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Achieving Early Target Trough Levels of Tacrolimus Using CYP3A5 Guided Dosing Versus Weight-based Dosing in a Multi-ethnic Population of Kidney Transplant Recipients in Singapore
Status: ACTIVE_NOT_RECRUITING
Conditions: Kidney Transplant Rejection|Kidney Transplant; Complications
Interventions: DRUG: Tacrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study to Compare Empagliflozin/ Metformin HCl 12.5mg/1000mg Film-coated Tablets
Status: COMPLETED
Conditions: Type2diabetes
Interventions: DRUG: Emapgliflozin/Metformin 12.5mg/1000mg Film-coated tablets|DRUG: Synjardy® 12.5mg/1000mg film-coated tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Pilot Study of an Internet-based Parenting Program for Child Disruptive Behavior
Status: COMPLETED
Conditions: Child Behavior Problem|Disruptive Behavior|Oppositional Defiant Disorder|Conduct Problems|Parent-Child Relations
Interventions: BEHAVIORAL: Family Check-up and Cognitive behavior therapy online: a Swedish internet-based parenting program|BEHAVIORAL: Family Check-up and Cognitive behavior therapy online: a Swedish internet-based parenting program with additional parental support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to Assess Safety, Tolerability, and Efficacy of HTL0018318 in Patients With Dementia With Lewy Bodies
Status: WITHDRAWN
Conditions: Dementia With Lewy Bodies
Interventions: DRUG: HTL0018318|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of BKM120 or BYL719 and Capecitabine in Patients With Metastatic Breast Cancer
Status: COMPLETED
Conditions: Metastatic Breast Cancer
Interventions: DRUG: BMK120|DRUG: Capecitabine|DRUG: BYL719|DRUG: Trastuzumab|DRUG: Lapatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Head Elevation on LMA Insertion
Status: COMPLETED
Conditions: Laryngeal Masks|Urinary Bladder Neoplasms
Interventions: PROCEDURE: Laryngeal mask airway insertion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Clinical Outcomes Study of the Nexel Total Elbow
Status: RECRUITING
Conditions: Elbow Joint Destruction|Post-traumatic Lesions|Ankylosed Joints|Advanced Rheumatoid Arthritis|Joint Instability or Loss of Motion|Acute Comminuted Articular Fracture of Elbow Joint Surfaces|Bone Loss Contributing to Elbow Instability|Bilateral Ankylosis From Causes Other Than Active Sepsis|Post-traumatic Arthritis|Degenerative Arthritis
Interventions: DEVICE: Nexel Total Elbow
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Surgical Procedures to Reduce Urinary Stress Incontinence
Status: COMPLETED
Conditions: Urinary Incontinence
Interventions: PROCEDURE: Burch Modified Tanagho|PROCEDURE: Autologous Fascia Sling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Person-Centred-Care on Antipsychotic Drug Use in Nursing Homes: a Cluster-randomised Trial
Status: COMPLETED
Conditions: Dementia
Interventions: OTHER: Person-centered Care|OTHER: Optimised Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Combination of Decitabine and Midostaurin in Patients Older Than 60 With Newly Diagnosed or Relapsed Refractory Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: combination therapy using decitabine and midostaurin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multi-Site Clinical Evaluation of the ARIES Bordetella Assay in Symptomatic Patients
Status: COMPLETED
Conditions: Bordetella Infections|Bordetella Pertussis Infection|Bordetella Parapertussis Infection
Interventions: DEVICE: ARIES Bordetella Assay
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety Assessment of Two Schedules of Intravenous Infusions of SNS-595 for the Treatment of Hematologic Malignancies
Status: COMPLETED
Conditions: Leukemia, Lymphocytic, Acute|Leukemia, Nonlymphocytic, Acute|Leukemia, Myeloid, Chronic|Myelodysplastic Syndromes
Interventions: DRUG: Vosaroxin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Incidence of Hypertrophic Cardiomyopathy in Infants of Diabetic Mothers Attending in NICU at Assiut University Children Hospital During One Year
Status: COMPLETED
Conditions: Hypertrophic Cardiomyopathy
Interventions: DIAGNOSTIC_TEST: echocardiography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: In Vivo Drug Interaction Pharmacokinetic Study of Tenofovir 1% Gel and Three Commonly Used Vaginal Products
Status: COMPLETED
Conditions: HIV Prevention
Interventions: DRUG: Tenofovir 1% gel|DRUG: Vaginal product
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Global Postural Re-education Program on Neck Pain in Breast Feeding Females.
Status: COMPLETED
Conditions: Neck Pain|Disability Physical|Breast Feeding
Interventions: OTHER: Global postural re-education program|OTHER: Conventional Physical Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of DLBS1425 as Neoadjuvant in Stage II or III Breast Cancer Patients
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: DLBS1425|DRUG: Placebo DLBS1425
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: 2-(1-{6-[(2-[F-18]Fluoroethyl) (Methyl)Amino]-2-naphthyl} Ethylidene) Malononitrile-PET for in Vivo Diagnose of Tauopathy in Unclassified Parkinsonism
Status: COMPLETED
Conditions: Progressive Supranuclear Palsy|Multi-System Atrophy|Parkinsonism
Interventions: DRUG: [F18]-FDDNP
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Study to Explore the Effects of Two Hour Inhalation of Ultrafine Carbon Black Particles on Airway Inflammation in Asthmatics
Status: COMPLETED
Conditions: Asthma
Interventions: PROCEDURE: Bronchoscopy|OTHER: Exposure to ultrafine carbon black particles
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Curing Atrial Fibrillation in Heart Failure
Status: COMPLETED
Conditions: Chronic Heart Failure|Atrial Fibrillation
Interventions: PROCEDURE: radiofrequency ablation|DRUG: ACE inhibitor - ramipril, enalapril, captopril, perindopril, lisinopril|DRUG: Beta Blocker (BB) - metoprolol, bisoprolol, carvedilol|DRUG: Aldosterone Antagonists - spironolactone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: NATriuretic Response to Expansion and dIUretics in huMans With Heart Failure
Status: COMPLETED
Conditions: Heart Failure
Interventions: DRUG: Ringer's (8.6 g/L sodium chloride, 0.33 g/L calcium chloride, 0.3 g/L potassium chloride) Solution|DRUG: Intravenous Bolus Furosemide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: How Hormones and Exposure and Response Prevention (EX/RP) Affect the Brain of People With OCD
Status: RECRUITING
Conditions: OCD
Interventions: BEHAVIORAL: Exposure & Response Prevention (EX/RP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Preventing Psychological Distress and Suicidal Behaviours: a Web-based and Mobile Suicide Prevention Intervention in the General Population
Status: UNKNOWN
Conditions: Suicide and Depression|Psychological Distress|Anxiety Disorders|Local Authorities Promotion
Interventions: OTHER: Promotion of the e-health tool by local authorities|OTHER: Promotion of the e-health tool by local authorities and GPs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Use of Directed Probiotics in ME/CFS: Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
Status: RECRUITING
Conditions: ME/CFS|IBS - Irritable Bowel Syndrome
Interventions: DRUG: Floradapt Intensive GI|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Combivent UDV (Ipratropium 500mcg and Salbutamol 2.5mg) and Salbutamol UDV Alone (2.5mg)
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: ipratropium plus salbutamol UDV|DRUG: salbutamol UDV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Development of Simulated Hippotherapy System and Investigation of Its Effectiveness in Children With Cerebral Palsy
Status: UNKNOWN
Conditions: Cerebral Palsy
Interventions: OTHER: Hippotherapy|OTHER: Neurodevelopmental Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of the Safety of and Immune Response to Varying Doses of a Vaccine Against COVID-19 in Healthy Adults
Status: COMPLETED
Conditions: Virus Diseases
Interventions: BIOLOGICAL: 1 µg CoV2 SAM (LNP)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Treatment of Post-partum Depression Using an Behavioral Intervention Called ROSE (Reach Out, Stay Strong, Essentials for Mothers of Newborns) Delivered Using an Electronic App
Status: RECRUITING
Conditions: Post-partum Depression
Interventions: DEVICE: InBloom|BEHAVIORAL: ROSE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Radiation Therapy in Treating Patients With Bone Metastases From Breast or Prostate Cancer
Status: COMPLETED
Conditions: Breast Cancer|Metastatic Cancer|Pain|Prostate Cancer
Interventions: PROCEDURE: pain therapy|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Idebenone in the Treatment of Mitochondrial Encephalopathy Lactic Acidosis & Stroke-like Episodes
Status: COMPLETED
Conditions: MELAS Syndrome
Interventions: DRUG: Idebenone|DRUG: Idebenone|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Metformin as add-on Therapy on Glycemic Control and Other Outcomes in Type 1 Diabetes
Status: UNKNOWN
Conditions: Type 1 Diabetes Mellitus|Metformin
Interventions: DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Novel Technique Lumber Spine Fusion: Unilateral Pedicular Screws Fixation Combined With Contralateral Interbody Cage
Status: UNKNOWN
Conditions: Treatment
Interventions: PROCEDURE: pedicle screw fixation on one side and intervertebral cage on the other sided|PROCEDURE: pedicle screw fixation and interbody cage on the same side
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Induction of Sensecence Using Dexamethasone to Re-sensitize NSCLC to Anti-PD1 Therapy
Status: TERMINATED
Conditions: Non-Small Cell Lung Cancer|Immunotherapy
Interventions: DRUG: Dexamthasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vulnerability/Resilience Factors Influencing the Developmental Trajectories and Adaptive Methods of Children and Adolescents in Child Welfare System.
Status: RECRUITING
Conditions: Behavior, Child|Child Development|Child Development Disorder|Adolescent Development|Adolescent Behavior|Child Mental Disorder|Child Behavior Disorders|Adolescent - Emotional Problem
Interventions: BEHAVIORAL: questionnaries, scales, cognitive tests
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy Study of Pre-emptive Etoricoxib for Postoperative Pain and Functional Outcome in Total Knee Arthroplasty
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: DRUG: Control|DRUG: Etoricoxib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Telmisartan and Amlodipine Fixed Dose Combination [FDC] Trial for the Treatment of Severe Hypertension
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: amlodipine|DRUG: telmisartan|DRUG: telmisartan and amlodipine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Ability of Lupron Depot to Enhance Immune Function Following Bone Marrow Transplantation
Status: TERMINATED
Conditions: Hodgkin Disease|Lymphoma, Non-Hodgkin|Multiple Myeloma|Mantle Cell Lymphoma
Interventions: DRUG: Leuprolide acetate depot (LAD) 11.25 mg 3 Month|DRUG: Matched placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vitamin D and Sexual Health
Status: COMPLETED
Conditions: Bacterial Vaginosis
Interventions: DIETARY_SUPPLEMENT: Vitamin D3 (cholecalciferol)|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Gemcitabine and Ifosfamide As a Second-Line Systemic Chemotherapy for Cisplatin -Failed Advanced TCC
Status: COMPLETED
Conditions: Transitional Cell Carcinoma
Interventions: DRUG: Gemcitabine, Ifosfamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability of HSC835 in Patients With Hematological Malignancies Undergoing Single Umbilical Cord Blood Transplant
Status: COMPLETED
Conditions: Single Umbilical Cord Blood Transplantation|Non-myeloablative Conditioning|Acute Lymphocytic Leukemia|Myelodysplastic Syndrome|Non-Hodgkin's Lymphoma|Multiple Myeloma|Chronic Lymphocytic Leukemia
Interventions: DRUG: HSC835
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of Open Angle Glaucoma or Ocular Hypertension in Patients Within Scandinavia
Status: COMPLETED
Conditions: Open Angle Glaucoma|Ocular Hypertension
Interventions: DRUG: timolol|DRUG: PhXA41
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: TOF Versus SOX in Metastatic Gastric Cancer
Status: COMPLETED
Conditions: Gastric Cancer
Interventions: DRUG: paclitaxel+oxaliplatin+fluorouracil|DRUG: oxaliplatin+S1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evertor Muscle Activity as a Predictor of Achilles Tenotomy in the Management of Idiopathic Varus Equinus Clubfoot
Status: RECRUITING
Conditions: Clubfoot
Interventions: OTHER: scale Idiopathic Clubfoot
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Duration of Postoperative Antibiotic Prophylaxis in Facial Fractures
Status: TERMINATED
Conditions: Surgical Wound Infection
Interventions: DRUG: Amoxicillin/clavulanic acid|DRUG: Amoxicillin plus placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Patient Activation Through Community Empowerment/Engagement for Diabetes Management (PACE-D)
Status: COMPLETED
Conditions: Diabetes Mellitus|Chronic Disease|Patient Care Planning|Patient Participation|Self Care|Empowerment
Interventions: OTHER: Intervention Group|OTHER: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Atopic Dermatitis With Different Orders of Application of Locoid Lotion and Hylatopic Plus Cream
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: Locoid Lipocream|DRUG: Hylatopic Plus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Electrical Pudendal Nerve Stimulation and Pelvic Floor Muscle Training for Female Stress Incontinence
Status: COMPLETED
Conditions: Stress Urinary Incontinence
Interventions: BEHAVIORAL: Electrical pudendal nerve stimulation|BEHAVIORAL: PFM training|BEHAVIORAL: Transvaginal ES
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Peer Mentor Intervention That Trains Black Men Who Have Sex With Men (BMSM) to Use and Promote Uptake of HIV/STI Self-Testing to Peers and Sex Partners: STAR Study (Self-Testing at Your Residence)
Status: COMPLETED
Conditions: HIV/AIDS|Sexually Transmitted Diseases
Interventions: BEHAVIORAL: Peer Mentor|BEHAVIORAL: Website only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Assessment of Esophageal Epithelium Integrity With Mucosal Impedance
Status: COMPLETED
Conditions: Gastroesophageal Reflux Disease (GERD)|Non-erosive Reflux Disease (NERD)
Interventions: PROCEDURE: Standard of Care esophagogastroduodenoscopy (EGD) with mucosal impedance testing
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Culturally Responsive Caregiver Support
Status: NOT_YET_RECRUITING
Conditions: Stress, Psychological|Adaptation, Psychological
Interventions: BEHAVIORAL: Education Support|BEHAVIORAL: Phone Call
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect Of Meal Frequency On Weight Loss And Body Composition Of Obese And Overweight Women
Status: COMPLETED
Conditions: Overweight and Obesity
Interventions: BEHAVIORAL: 3 meals+3 snacks|BEHAVIORAL: 3 meals
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Pharmacokinetics of Multiple Rising Doses of BI 201335 NA in Healthy Male Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BI 201335 NA|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Feasibility of Specific Anesthesia of the Forefoot Preserving the Sensitivity of the Heel for Foot Surgery
Status: COMPLETED
Conditions: Hallux Valgus and Bunion (Disorder)|Morton Neuroma|Metatarsal Fracture|Ingrown Nail|Foot Wound|Foot Infection
Interventions: PROCEDURE: Specific block of medial and lateral plantar nerves
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Comparison of Different Propofol Formulations With or Without Remifentanil
Status: COMPLETED
Conditions: Anesthesia
Interventions: DRUG: Propofol (Astra-Zeneca), NaCl 0.9%|DRUG: propofol 1% (Astra-Zeneca) and remifentanil|DRUG: propofol 1% (Astra-Zeneca) and remifentanil|DRUG: Propofol (Astra-Zeneca), NaCl 0.9%|DRUG: Propofol (Astra-Zeneca) and remifentanil|DRUG: Propofol (Astra-Zeneca) and remifentanil|DRUG: Propofol (B-Braun) and NaCl 0.9%|DRUG: Propofol (B-Braun) and remifentanil|DRUG: Propofol (B-Braun) and remifentanil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Rural Community Peer Partnerships for Improving Methamphetamine-Associated Heart Failure Screening and Engagement
Status: RECRUITING
Conditions: Methamphetamine Use|Heart Failure
Interventions: OTHER: Treatment as Usual|OTHER: Telehealth-Cardiology
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Effect of Propranolol on Preventing Posttraumatic Stress Disorder
Status: COMPLETED
Conditions: Post-Traumatic Stress Disorder
Interventions: DRUG: Propranolol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: On-label tReatment With Intravitreal Aflibercept injectiOn for Patients With Persistent Pigment epitheliaL Detachments in Neovascular Age Related Macular Degeneration (AMD)
Status: UNKNOWN
Conditions: Age Related Macular Degeneration|Pigment Epithelial Detachment
Interventions: DRUG: Aflibercept
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study Of Nivolumab/ Bevacizumab/Rucaparib
Status: ACTIVE_NOT_RECRUITING
Conditions: Peritoneal Cancer|Ovarian Cancer|Fallopian Tube Cancer
Interventions: DRUG: Bevacizumab|DRUG: Nivolumab|DRUG: Rucaparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Targeted Reinnervation for Neuromas as a Means to Improve Prosthesis Control in Major Limb Amputation
Status: COMPLETED
Conditions: Neuroma|Pain|Prosthesis User|Prosthesis Failure
Interventions: PROCEDURE: Targeted Muscle Reinnervation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: LEO 90100 Twice Weekly Maintenance Regimen for Psoriasis Vulgaris
Status: COMPLETED
Conditions: Psoriasis Vulgaris
Interventions: DRUG: LEO 90100 aerosol foam|DRUG: LEO 90100 aerosol foam vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing GLIADEL to Stereotactic Radiosurgery in Metastatic Brain Disease
Status: RECRUITING
Conditions: Brain Tumor - Metastatic
Interventions: DRUG: Carmustine 7.7Mg Wafer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lorlatinib in Combination With Chemotherapy in Participants With Metastatic Anaplastic Lymphoma Kinase Positive (ALK+) Non-small Cell Lung Cancer (NSCLC) Who Progressed on Single-agent Lorlatinib
Status: WITHDRAWN
Conditions: Lung Cancer|Non-small Cell Lung Cancer
Interventions: DRUG: Lorlatinib|DRUG: Cisplatin or Carboplatin|DRUG: Pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of ALXN1820 in Healthy Adult Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: ALXN1820 SC|DRUG: ALXN1820 IV|DRUG: Placebo SC|DRUG: Placebo IV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Phase Ⅲ Randomized Clinical Trial of Postmastectomy Hypofractionation Radiotherapy in High-risk Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: RADIATION: hypofractionation radiotherapy|RADIATION: conventional fractionation radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Patient Activation After DXA Result Notification
Status: COMPLETED
Conditions: Osteoporosis|Bone Diseases, Metabolic
Interventions: BEHAVIORAL: Bone Mineral Density Result Letter and Bone Health Brochure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Phase 3 Study to Evaluate Efficacy of Amifampridine Phosphate in Lambert-Eaton Myasthenic Syndrome (LEMS)
Status: COMPLETED
Conditions: Lambert-Eaton Myasthenic Syndrome
Interventions: DRUG: Amifampridine Phosphate|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Height Adjusted Versus Standardized Dose of Bupivacaine for Spinal Anesthesia
Status: NOT_YET_RECRUITING
Conditions: Regional Anesthesia Morbidity|Cesarean Section Complications|Local Anesthetic Complication
Interventions: OTHER: standardized dose|OTHER: adjusted dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Research Study to Compare Two Different Forms of Once-weekly Semaglutide in Two Different Injection Pens
Status: COMPLETED
Conditions: Overweight|Obesity
Interventions: DRUG: Semaglutide (administered by DV3396 pen-injector)|DRUG: Semaglutide (administered by PDS290 pen-injector)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pre-Prostatectomy Celecoxib or Placebo
Status: TERMINATED
Conditions: Adenocarcinoma of the Prostate|Prostate Cancer
Interventions: DRUG: Celecoxib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cisplatin, Metronomic Low-Dose Interferon Alfa, Gemcitabine, and Fever-Range Whole-Body Hyperthermia in Treating Patients With Inoperable or Metastatic Pancreatic Cancer
Status: UNKNOWN
Conditions: Pancreatic Cancer
Interventions: BIOLOGICAL: recombinant interferon alfa|DRUG: cisplatin|DRUG: gemcitabine hydrochloride|PROCEDURE: hyperthermia treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The New LC-MS/MS Method for Determination of Unbound Tacrolimus in Plasma
Status: UNKNOWN
Conditions: Immunosuppression|Kidney Transplant Rejection|Kidney Transplant; Complications|Liver Transplant Rejection|Liver Transplant; Complications|Metabolism Medication Toxicity|Genetic Predisposition
Interventions: DRUG: Tacrolimus|DIAGNOSTIC_TEST: Unbound tacrolimus measurement|DIAGNOSTIC_TEST: CYP3A4 and CYP3A5 genotyping
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of the Effect of Kinesio Taping and Proprioceptive Exercise on the Stability of Ankle in Amateur Soccer Players
Status: COMPLETED
Conditions: Injury of Musculoskeletal System
Interventions: OTHER: Kinesio taping|OTHER: Proprioceptive exercises|OTHER: Placebo Kinesio taping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Soft Tissue Massage Along With Mobilization Technique on Symptoms and Functional Status of Carpal Tunnel Syndrome
Status: UNKNOWN
Conditions: Carpal Tunnel Syndrome
Interventions: OTHER: Soft tissue mobilization|OTHER: Joint and nerve mobilization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sintilimab and Nimotuzumab Combined With Chemotherapy for the Treatment of R/M HNSCC.
Status: UNKNOWN
Conditions: Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma
Interventions: DRUG: Nimotuzumab|DRUG: Sintilimab|DRUG: Chemotherapy drug
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of Ustekinumab for Subjects With Chronic Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: Ustekinumab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: LCH-IV, International Collaborative Treatment Protocol for Children and Adolescents With Langerhans Cell Histiocytosis
Status: RECRUITING
Conditions: Langerhans Cell Histiocytosis
Interventions: DRUG: Prednisone|DRUG: Vinblastine|DRUG: mercaptopurine|DRUG: INDOMETHACIN|DRUG: Methotrexate|DRUG: Cytosine Arabinoside|DRUG: 2-chlorodeoxyadenosine|PROCEDURE: hematopoietic stem cell transplantation (RIC-HSCT)|BIOLOGICAL: Intravenous immunoglobulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nab-Paclitaxel in Combination With Carboplatin as First-line Therapy in Patients With NSCLC
Status: COMPLETED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: Nab-Paclitaxel|DRUG: Carboplatin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Comparison of Lumbopelvic Stabilisation and Pelvic Floor Exercises on the Stress Incontinence
Status: UNKNOWN
Conditions: Stress Urinary Incontinence|Pelvic Floor Disorders
Interventions: BEHAVIORAL: Lumbopelvic Stabilisation Exercises Group|BEHAVIORAL: Pelvic Floor Exercises Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Open Technique Erector Spinae Plane Block in Spinal Surgery
Status: NOT_YET_RECRUITING
Conditions: Postoperative Pain|Erector Spinae Plane Block in Spinal Surgery
Interventions: PROCEDURE: Erector spinae plane block|PROCEDURE: Erector spinae plane block performed by surgeon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: DANISH-CRT - Does Electric Targeted LV Lead Positioning Improve Outcome in Patients With Heart Failure and Prolonged QRS
Status: RECRUITING
Conditions: Heart Failure|Branch Block, Bundle
Interventions: DEVICE: Implantation of a Cardiac Resynchronisation Therapy (CRT) pacing device with or without Implanted Cardioverter Defibrillator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect on Thirst, Nausea-Vomiting and Comfort Levels of Menthol Lozenge Applied After Extubation
Status: COMPLETED
Conditions: Nausea|Vomiting|Thirst
Interventions: OTHER: Menthol Lozenge
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: pBFS Guided Precision Neuromodulation Treatment for ASD
Status: RECRUITING
Conditions: Autism Spectrum Disorder
Interventions: DEVICE: active iTBS|DEVICE: sham iTBS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Studying Dexamethasone and Prednisone Sensitivity in Samples From Younger Patients With High-Risk B-Cell Precursor Acute Lymphoblastic Leukemia
Status: COMPLETED
Conditions: Leukemia
Interventions: GENETIC: DNA analysis|GENETIC: RNA analysis|GENETIC: gene expression analysis|OTHER: laboratory biomarker analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of PF-08046054/SGN-PDL1V in Advanced Solid Tumors
Status: RECRUITING
Conditions: Carcinoma, Non-Small-Cell Lung|Squamous Cell Carcinoma of the Head and Neck|Esophageal Squamous Cell Carcinoma|Ovarian Neoplasms|Melanoma|Triple Negative Breast Neoplasms|Gastric Cancer
Interventions: DRUG: PF-08046054|DRUG: pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multi-site Adaptive Trials for COVID-19
Status: COMPLETED
Conditions: COVID-19
Interventions: DRUG: SOC + Intravenous Famotidine|DRUG: SOC + Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Relation of Morphine-induced Itch and Pain Processing
Status: COMPLETED
Conditions: Morphine|Itch
Interventions: DRUG: Morphine|DRUG: Placebo oral tablet|DRUG: Histamine|DRUG: Cowhage (Mucuna Pruriens)|DRUG: isotonic saline|DRUG: Histamine|DRUG: Cowhage (Mucuna Pruriens)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Evaluate the Effect of Ketoconazole and Rifampicin on the Pharmacokinetics of Fimasartan in Healthy Male Volunteers
Status: COMPLETED
Conditions: Essential Hypertension
Interventions: DRUG: Fimasartan, Ketoconazole, Rifampicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Chest Tube Drainage or Thoracoscopic Surgery for Failed Aspiration of Spontaneous Pneumothorax
Status: UNKNOWN
Conditions: Pneumothorax
Interventions: PROCEDURE: Video-assisted thoracoscopic surgery|PROCEDURE: chest tube drainage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of NM8074 in Patients With Anti-Neutrophil Cytoplasmic Antibody (ANCA)-Associated Vasculitis (AAV)
Status: NOT_YET_RECRUITING
Conditions: Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis
Interventions: DRUG: NM8074|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Efficacy of Skin Rejuvenation Therapy in Combination With Neurotoxin and Full Facial Filler Treatments
Status: COMPLETED
Conditions: Subjects Requesting and Requiring Facial Rejuvenation With Neurotoxins and/or Hyaluronic Acid Fillers
Interventions: OTHER: NuDerm® System|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Pharmacokinetic Study of the Effect of Itraconazole Exposure to Orvepitant in Healthy Volunteers
Status: COMPLETED
Conditions: Pharmacokinetic Study in Healthy Male Volunteers
Interventions: DRUG: Orvepitant|DRUG: Itraconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Integrated Versus Parallel Connection for Renal Replacement Therapy in ECMO Patients
Status: RECRUITING
Conditions: Venoarterial Extracorporeal Membrane Oxygenation|Renal Replacement Therapy|Acute Kidney Injury
Interventions: PROCEDURE: Parallel connection|PROCEDURE: Integrated connection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Rituximab in Acute Cellular Rejection in Renal Transplant Patients
Status: TERMINATED
Conditions: Acute Rejection
Interventions: DRUG: Rituximab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Mipasetamab Uzoptirine (ADCT-601) in Participants With Solid Tumors
Status: RECRUITING
Conditions: Advanced Solid Tumors
Interventions: DRUG: ADCT-601|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Q Revascularization System for Neurointervention in Acute Ischemic Stroke
Status: COMPLETED
Conditions: Acute Stroke|Cerebral Ischemia
Interventions: DEVICE: Q Revascularization System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Identify and Describe Predictive Factors for Thromboembolic Events in Patients With High-risk Polycythemia Vera
Status: ACTIVE_NOT_RECRUITING
Conditions: Polycythemia Vera
Interventions: OTHER: Hydroxyurea|OTHER: Ruxolitinib
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Personalized Obesity Management - Matching Dietary Fibers and Microbial Enterotype
Status: COMPLETED
Conditions: Overweight and Obesity|Weight Loss
Interventions: DIETARY_SUPPLEMENT: Arabinoxylan|DIETARY_SUPPLEMENT: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Semi-permanent Acupuncture Effect on Cervical Ripening
Status: NOT_YET_RECRUITING
Conditions: Pregnancy Complications
Interventions: OTHER: Semi-permanent acupuncture|OTHER: Sham of semi-permanent acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Validation of a Digital Self-Administered Cognitive Screening Tool: MoCA-XpressO
Status: ACTIVE_NOT_RECRUITING
Conditions: Cognitive Impairment|Cognitive Change|Cognitive Deficit|Assessment, Self
Interventions: DIAGNOSTIC_TEST: MoCA-Xpresso
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SCREENING
Clinical trial: Study Comparing Ranibizumab Monotherapy With Combined Verteporfin Therapy in Subfoveal CNV
Status: COMPLETED
Conditions: Choroidal Neovascularization|Age-Related Macular Degeneration
Interventions: DRUG: intravitreal ranibizumab|DRUG: intravitreal ranibizumab & photodynamic therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study to Determine the Efficacy and Safety of Sivelestat in Subjects With Acute Lung Injury
Status: COMPLETED
Conditions: Respiratory Distress Syndrome, Adult|Acute Lung Injury
Interventions: DRUG: Sivelestat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Carboxytherapy Versus Short-pulsed Nd Yag Laser in Cellulite
Status: UNKNOWN
Conditions: Efficacy of Treatment of Cellulite Using Carboxy Therapy
Interventions: DEVICE: Carboxytherapy, short pulsed 1064 Nd Yag laser and subcision
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Copanlisib Combined With Rucaparib in Patients With Metastatic Castration-resistant Prostate Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Castration-resistant Prostate Cancer
Interventions: DRUG: Rucaparib|DRUG: Copanlisib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Platelet Rich Plasma vs. Corticosteroid Injection in the Treatment of Partial Rotator Cuff Tears
Status: TERMINATED
Conditions: Rotator Cuff Tear
Interventions: BIOLOGICAL: Platelet Rich Plasma (PRP)|DRUG: Corticosteroid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sleeve Gastrectomy and Roux-en-Y Gastric Bypass in the Treatment of Type 2 Diabetes Mellitus.
Status: RECRUITING
Conditions: Obesity|Type 2 Diabetes|Bariatric Surgery
Interventions: PROCEDURE: Roux-en-Y gastric bypass|PROCEDURE: sleeve gastrectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Integrated Neuromuscular Inhibition, Muscle Energy and Strain Counter Strain Techniques in Neck Pain
Status: COMPLETED
Conditions: Neck Pain
Interventions: OTHER: Strain Counter Strain Technique|OTHER: Muscle Energy Technique,|OTHER: Integrated Neuromuscular Inhibition Technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Clinical Trial of Gintuit (TM)in Establishing a Functional Zone of Attached Gingiva
Status: COMPLETED
Conditions: Gingival Recession
Interventions: DEVICE: Gintuit|OTHER: autologous Free Gingival Graft (FGG)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Palmitoylethanolamide for Chronic Inflammatory Pain Conditions
Status: RECRUITING
Conditions: Chronic Pain
Interventions: DRUG: Palmitoylethanolamide 600mg twice a day|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of PPB Using 10, 20 and 30 ml of Lidocaine, Study on Volunteers
Status: COMPLETED
Conditions: Knee Arthritis|Anesthesia, Local|Post Surgical Pain
Interventions: DRUG: Popliteal Plexus Block with 10 ml|DRUG: Popliteal Plexus Block with 20 ml|DRUG: Popliteal Plexus Block with 30 ml|DRUG: Femoral Nerve Block|DRUG: Sciatic Nerve Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Preemptive Dexamethasone , Paracetamol on Postoperative Period Following Adeno-tonsillectomy in Pediatric .
Status: COMPLETED
Conditions: Analgesia
Interventions: DRUG: paracetamol|DRUG: Dexamethasone|DRUG: normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Leish-111f + MPL-SE Vaccine in Healthy Adults Not Previously Exposed to Leishmania Parasite
Status: COMPLETED
Conditions: Cutaneous Leishmaniasis
Interventions: BIOLOGICAL: Leish-111f + MPL-SE vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Continuous Versus Discontinuous Design of Encircling Lesions During Ablation for Atrial Fibrillation
Status: UNKNOWN
Conditions: Atrial Fibrillation
Interventions: PROCEDURE: catheter ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Atrial Fibrillation: Risk and Benefits of Anti-coagulation in the Elderly
Status: COMPLETED
Conditions: Anticoagulants Causing Adverse Effects in Therapeutic Use|Atrial Fibrillation|Frail Elderly Syndrome
Interventions: DRUG: Anticoagulants
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of Apricoxib (Selective Cyclooxygenase 2 Inhibition) in Modulating T Regulatory Cells of Patients With Early Stage Non-small Cell Lung Cancer
Status: TERMINATED
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: Apricoxib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Use of Heliox Associated With PEEP in Patients With Asthma
Status: COMPLETED
Conditions: Asthma|Helium|Oxygen|Positive End-Expiratory Pressure
Interventions: OTHER: Heliox+PEP|OTHER: Oxygen+PEP|OTHER: Heliox|OTHER: Oxygen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Stress and Anxiety for Patients Undergoing MRI Using, Holy Quran, Music, and Natural Sounds
Status: COMPLETED
Conditions: Anxiety|Stress|MRI Contrast Media Adverse Reaction
Interventions: BEHAVIORAL: Listening to either Quran, Music, and or Natural sound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: 19/5000 (SYNAPSOT21) Predictive Factors of Sleep Apnea Syndrome in Down Syndrome
Status: COMPLETED
Conditions: Down Syndrome|Sleep Apnea, Obstructive|Polysomnography
Interventions: DIAGNOSTIC_TEST: Assessment of OSAS predictive factors
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p