pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Efficacy and Safety Study of Miconazole Lauriad to Treat Oropharyngeal Candidiasis in HIV Patients
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: miconazole Lauriad|DRUG: Clotrimazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Proof of Concept Study to Determine the Safety and Antiviral Effect of BZF961 With or Without Ritonavir Boosting in Hepatitis C Virus Infected Patients
Status: COMPLETED
Conditions: Hepatitis C
Interventions: DRUG: BZF961|DRUG: Ritonavir|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Entecavir and Pegasys Sequential Therapy Versus Pegasys for HBeAg Positive Chronic Hepatitis B
Status: UNKNOWN
Conditions: Hepatitis B, Chronic
Interventions: DRUG: Entecavir and peginterferon alfa-2a|DRUG: Placebo and peginterferon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Early Versus Delayed Enteral Feeding and Omega-3 Fatty Acid/Antioxidant Supplementation for Treating People With Acute Lung Injury or Acute Respiratory Distress Syndrome (The EDEN-Omega Study)
Status: TERMINATED
Conditions: Respiratory Distress Syndrome, Adult
Interventions: BEHAVIORAL: Minimal (Trophic) Feeding|BEHAVIORAL: Full Feeding|DIETARY_SUPPLEMENT: Omega-3 Fatty Acids and Antioxidant Supplements|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Kava Kava for the Treatment of Generalized Anxiety Disorder (GAD)
Status: TERMINATED
Conditions: Anxiety Disorders
Interventions: DRUG: Venlafaxine ER|DRUG: Sugar pill|DRUG: Kava
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Oral Omega-3 for Reduction of Kidney Scar Due to Pyelonephritis in Children
Status: UNKNOWN
Conditions: Acute Pyelonephritis(APN)
Interventions: DRUG: Omega-3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Effects of Vitamin D on Angiogenic Factors in Women With Polycystic Ovary Syndrome
Status: COMPLETED
Conditions: Polycystic Ovary Syndrome|Vitamin D Deficiency
Interventions: DRUG: Vitamin D3|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Surgical Resection of Synchronous Pulmonary or Hepatic Oligometastatic Pancreatic Ductal Adenocarcinoma
Status: RECRUITING
Conditions: Pancreatic Ductal Adenocarcinoma|Oligometastatic Disease
Interventions: PROCEDURE: Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Functional Mobility in the Elderly: Influence of Morphological, Neuromuscular and Training Parameters
Status: COMPLETED
Conditions: Aging
Interventions: OTHER: Concentric training|OTHER: Concentric-Eccentric training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SIPLIZUMAB in AILD and LT
Status: NOT_YET_RECRUITING
Conditions: Autoimmune Liver Disease|Liver Transplant Disorder|Autoimmune Hepatitis|Primary Sclerosing Cholangitis|End Stage Liver DIsease|Cirrhosis, Liver
Interventions: DRUG: Siplizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Bruton's Tyrosine Kinase (BTK) Inhibitor Ibrutinib in Participants With Relapsed or Refractory Mantle Cell Lymphoma
Status: COMPLETED
Conditions: Lymphoma, Mantle-cell
Interventions: DRUG: Ibrutinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Efficacy and Safety of Entelon 50mg in Patients With Non-Proliferative Diabetic Retinopathy
Status: RECRUITING
Conditions: Non Proliferative Diabetic Retinopathy
Interventions: DRUG: Entelon Tab. 50mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Using Multiparametric MRI to Evaluate Intraprostatic Tumor Responses and Androgen Resistance Patterns in Newly Diagnosed Prostate Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Cancer
Interventions: DRUG: Goserelin|DRUG: Enzalutamide|DEVICE: mpMRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Topical 0.01% Atropine for the Control of Fast Progressing Myopia
Status: TERMINATED
Conditions: Myopia Progressing|Childhood
Interventions: DRUG: Atropine 0.01%|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cerebrovascular Effects of the Use of Alpha-stat or pH-stat Management of Cardiopulmonary Bypass
Status: UNKNOWN
Conditions: Diabetes Mellitus|Cardiac Surgical Procedures
Interventions: PROCEDURE: Elective cardiopulmonary bypass (CPB)|PROCEDURE: Alpha-stat acid-base management|PROCEDURE: pH-stat acid-base management
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: IV Acetaminophen for Postoperative Pain Analgesia After Laparoscopic Hysterectomy
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: IV acetaminophen|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Adjuvant PRGN-2012 in Adult Patients With Recurrent Respiratory Papillomatosis
Status: ACTIVE_NOT_RECRUITING
Conditions: Recurrent Respiratory Papillomatosis|Papillomavirus Infections|Papillomaviridae
Interventions: DRUG: PRGN-2012
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intense Pulsed Light Study for Dry Eye Disease
Status: COMPLETED
Conditions: Dry Eyes Chronic
Interventions: DEVICE: Intense Pulsed Light Therapy|PROCEDURE: Sham Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Tissue Samples in Predicting How Well Chemotherapy and Radiation Therapy Will Kill Cancer Cells in Patients With Squamous Cell Carcinoma of the Esophagus
Status: UNKNOWN
Conditions: Esophageal Cancer
Interventions: DRUG: cisplatin|DRUG: fluorouracil|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radiomics to Identify Patients at Risk for Developing Pneumonitis, Differentiate Immune Checkpoint Inhibitor-induced Pneumonitis From Other Lung Inflammation and Distinguish Tumour Pseudo-progression From Real Tumour Growth
Status: COMPLETED
Conditions: Stage IV Non-small Cell Lung Cancer
Interventions: OTHER: No interventions
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Novel Technique Versus Conventional Subepithelial Connective Tissue Graft in Treatment of Ridge Contour Defects
Status: RECRUITING
Conditions: Defect in Alveolar Ridge
Interventions: PROCEDURE: DIPRF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mosunetuzumab in Patients With Newly Diagnosed Extranodal Marginal Zone Lymphoma
Status: NOT_YET_RECRUITING
Conditions: Extranodal Marginal Zone Lymphoma
Interventions: DRUG: Mosunetuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Bortezomib-containing Regimens in Newly Diagnosed Patients With t (4; 14) Positive Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Bortezomib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of Mask on Functional Capacity and Quality of Life During Controlled Endurance Exercise in Sedentary Adults
Status: UNKNOWN
Conditions: Sedentary Adults
Interventions: DEVICE: Treadmill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: DEXamethasone EARLY Administration in Hospitalized Patients With Covid-19 Pneumonia
Status: RECRUITING
Conditions: COVID-19|Acute Respiratory Distress Syndrome|Pneumonia, Viral
Interventions: DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Synaptic Density and Progression of Huntington's Disease.
Status: COMPLETED
Conditions: Huntington Disease
Interventions: DIAGNOSTIC_TEST: 11C-UCB-J PET-CT|DIAGNOSTIC_TEST: 18F-FDG PET-MR
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Can Ultrasound be Used as a Measure of Muscle Quality? A Validation Study Comparing Ultrasound With MRI and MRS in Older and Younger Persons.
Status: COMPLETED
Conditions: Muscle Atrophy
Interventions: DIAGNOSTIC_TEST: MRI, MRS|DIAGNOSTIC_TEST: Ultrasound
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study to Evaluate the Pharmacokinetics, Pharmacodynamics, and Safety of Armodafinil in Children and Adolescents With Excessive Sleepiness Associated With Narcolepsy
Status: COMPLETED
Conditions: Narcolepsy
Interventions: DRUG: Armodafinil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study of OsrHSA in Patients With Decompensated Cirrhotic Ascites
Status: RECRUITING
Conditions: Cirrhotic Ascites
Interventions: DRUG: OrsHSA|DRUG: HSA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Human Urinary Kallidinogenase on Early Improvement and Functional Outcomes in Acute Ischemic Stroke (TK-SPEED)
Status: NOT_YET_RECRUITING
Conditions: Acute Ischemic Stroke|Functional Outcomes
Interventions: DRUG: Human Urinary Kallidinogenase|OTHER: Clinical Routine Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Optimising Community Antibiotic Use and Infection Control With Behavioural Interventions in Burkina Faso and DR Congo
Status: ENROLLING_BY_INVITATION
Conditions: Antimicrobial Stewardship|Drug Resistance, Bacterial
Interventions: BEHAVIORAL: Behavioural intervention bundle to optimise antibiotic use and reduce the risk of human-to-human or environmental-animal-human transmission
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Conservative Treatment Compared to Osteosynthesis in Patients With a Fractured Collar Bone
Status: COMPLETED
Conditions: Displaced Midshaft Fracture of the Collar Bone
Interventions: PROCEDURE: Operation using a precontoured titanium plate and screws|PROCEDURE: Displaced midshaft fracture of the collar bone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacodynamic Effects of a Free-Fatty Acid Formulation of Omega-3 Pentaenoic Acid in Adults With Hypertriglyceridemia
Status: COMPLETED
Conditions: Hypertriglyceridemia
Interventions: DRUG: Omega 3 pentaenoic acid|DRUG: icosapent ethyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Anesthetics on Oxidative Stress and Apoptosis Status in Children
Status: COMPLETED
Conditions: Anesthesia, General
Interventions: DRUG: Sevoflurane|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Early Routine vs. Selective Human Milk Fortification in Extremely Preterm Infants
Status: RECRUITING
Conditions: Poor Growth in Extremely Preterm Infants|Necrotizing Enterocolitis
Interventions: DIETARY_SUPPLEMENT: Routine vs Selective use of Human Milk Donor Fortifier
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study of Ruxolitinib Cream for the Treatment of Discoid Lupus Erythematosus
Status: COMPLETED
Conditions: Discoid Lupus Erythematosus
Interventions: DRUG: Ruxolitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Renal Allograft Tolerance Through Mixed Chimerism - SMC/MGH
Status: RECRUITING
Conditions: Renal Failure
Interventions: DRUG: Rituximab, Fludarabine, Cyclophosphamide, Thymic irradiation and Siplizumab|PROCEDURE: Combined bone marrow and kidney transplant
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Alpha Auditory Entrainment for Cognitive Enhancement and Sensory Hypersensitivity in Youth With Developmental Disorders
Status: RECRUITING
Conditions: Fragile X Syndrome|Autism Spectrum Disorder|Autistic Disorder|Asperger Syndrome
Interventions: OTHER: Alpha Auditory Entrainment|OTHER: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multiprofessional Approach in Diabetes Mellitus
Status: UNKNOWN
Conditions: Diabetes Mellitus, Type 2
Interventions: BEHAVIORAL: Specific and educational guidelines on care for pathology (diabetes mellitus) according to each profession involved in the research
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: The ImPreSS Trial: Pharmacogenomic Decision Making at Time of Surgery
Status: RECRUITING
Conditions: Surgery
Interventions: PROCEDURE: Routine Elective Surgery- In patient or out patient elective surgery|DIAGNOSTIC_TEST: Blood test for genetic testing|OTHER: Drug-genetic Profile
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: An Observational Study to Investigate the Use of Aflibercept 8 mg to Treat Adult Patients With Neovascular Age-Related Macular Degeneration (nAMD) and Diabetic Macular Edema (DME) in a Real-World Setting
Status: NOT_YET_RECRUITING
Conditions: Neovascular Age-related Macular Degeneration (nAMD)|Wet Age-related Macular Degeneration (AMD)|Diabetic Macular Edema (DME)|Visual Impairment
Interventions: DRUG: aflibercept 8 mg
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Randomized Trial Comparing 2 Methods for Rapid Induction of Cooling in Stroke Patients, Cold Infusions vs. EMCOOLS Brain.Pad (iCOOL 3)
Status: COMPLETED
Conditions: Ischemic Stroke|Hemorrhagic Stroke
Interventions: DRUG: Cold crystalloid infusions, 0.9%NaCl or Ringer's|DEVICE: EMCOOLS Brain.Pad
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immediate Release Versus Slow Release Carvedilol in Heart Failure
Status: UNKNOWN
Conditions: Heart Failure With Reduced Ejection Fraction
Interventions: DRUG: CarVeDilol-SR (Slow Release)|DRUG: Carvedilol IR (Immediate Release)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: aDjunct bicarbonatE in Local anaesthesIa for CarpAl Tunnel rElease (DELICATE)
Status: RECRUITING
Conditions: Carpal Tunnel Syndrome
Interventions: OTHER: Sodium bicarbonate|OTHER: Control arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Armodafinil (Nuvigil), Postoperative Recovery of OSA (Obstructive Sleep Apnea) and Obese Patients
Status: COMPLETED
Conditions: Obesity|Premature Recovery From Anesthesia
Interventions: DRUG: Nuvigil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Ablation Efficacy of Contact Side Firing Fiber in Predefined Settings for Treating BPH
Status: TERMINATED
Conditions: Treatment of Benign Prostatic Hyperplasia
Interventions: DEVICE: Lumenis Pulse P120H and Xpeeda side firing fiber
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of a Biopsychosocial-Spiritual Group Intervention on Quality of Life of Institutionalized Seniors
Status: COMPLETED
Conditions: Quality of Life
Interventions: BEHAVIORAL: the Biopsychosocial-Spiritual Group Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pharmacokinetic Study of Cabotegravir and Rilpivirine Long-acting Intramuscular Injections in Healthy Adult Participants
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Cabotegravir Tablets|DRUG: Rilpivirine Tablets|DRUG: Cabotegravir extended release suspension for injection (long-acting)|DRUG: Rilpivirine extended release suspension for injection (long-acting)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Efficacy and Safety of ABTL0812
Status: COMPLETED
Conditions: Endometrial Cancer|Squamous Non-Small Cell Lung Cancer
Interventions: DRUG: ABTL0812 in combination with paclitaxel and carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Human Menopausal Gonadotropin Combining With Human Chorionic Gonadotropin Treat Congenital Hypogonadotropic Hypogonadism
Status: UNKNOWN
Conditions: Kallmann Syndrome|Hypogonadotropic Hypogonadism
Interventions: DRUG: Human Menopausal Gonadotropin|DRUG: Human Chorionic Gonadotropin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Bioequivalence Study Between Fluticasone Propionate 250 mcg and Salmeterol Xinafoate 50 mcg Inhalation Powder/Respirent Pharmaceuticals vs. ADVAIR DISKUS® 250/50 Inhalation Powder/GSK in Healthy Volunteers
Status: COMPLETED
Conditions: Bioequivalence
Interventions: DRUG: Test Product|DRUG: Reference Product
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Crossover Comparison of MultiHance and Dotarem
Status: COMPLETED
Conditions: Brain Disease
Interventions: DRUG: MultiHance 0.1 mmol/kg|DRUG: Dotarem|DRUG: MultiHance 0.05 mmol/kg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: ALK21-021: A Safety Study of Medisorb® Naltrexone (VIVITROL®) Administered to Health Care Professionals
Status: COMPLETED
Conditions: Opiate Dependence
Interventions: DRUG: Medisorb naltrexone 380 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Vitamin D Supplement in Induction of Ovulation in Overweight Women With Polycystic Ovary Syndrome
Status: UNKNOWN
Conditions: Ovulation Induction
Interventions: DRUG: Vitamin D with calcium and clomiphene citrate|DRUG: Placebo Oral Tablet with calcium and clomiphene citrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: US Guided EOI Block Versus ESPB for Postoperative Analgesia in Laparoscopic Cholecystectomy
Status: RECRUITING
Conditions: Postoperative Pain
Interventions: OTHER: External oblique intercostal (EOI) block|OTHER: Erector spinae plane block (ESPB)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of ALND With Vein Branches Reservation on Postoperative Upper Limb Edema and Dysfunction in Breast Cancer
Status: RECRUITING
Conditions: Breast Cancer Lymphedema
Interventions: PROCEDURE: axillary lymph node dissection with vein branches reservation|PROCEDURE: axillary lymph node dissection without vein branches reservation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Acute Effects of Vildagliptin on Gastric Emptying in Patients With Type 2 Diabetes.
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Vildagliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Donor Umbilical Cord Blood Transplant By Injection Into the Bone Marrow in Treating Patients With Hematologic Cancer
Status: TERMINATED
Conditions: Myeloproliferative Disorders|Leukemia|Lymphoma|Myelodysplastic Syndromes
Interventions: PROCEDURE: umbilical cord blood transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Analysis of Immuno-Nutrition Index in Advanced Gastric Cancer Receiving Preoperative Treatments
Status: RECRUITING
Conditions: Gastric Cancer|Neoadjuvant Chemotherapy|Neoadjuvant Chemoradiotherapy|Systemic Inflammatory Response Syndrome (SIRS)|Nutrition Aspect of Cancer
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: PROCLAIM: Effect of AC2592 Administered by Continuous Subcutaneous Infusion in Subjects With Advanced Chronic Congestive Heart Failure
Status: COMPLETED
Conditions: Congestive Heart Failure
Interventions: DRUG: AC2592|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Fluorescence-guided Surgery for Low- and High-grade Gliomas
Status: COMPLETED
Conditions: Glioma
Interventions: DRUG: 5-Aminolevulinic acid (ALA)|DRUG: Placebo - ascorbic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of NST-6179 in Adult Subjects With Intestinal Failure-Associated Liver Disease (IFALD).
Status: RECRUITING
Conditions: Intestinal Failure Associated Liver Disease
Interventions: DRUG: NST-6179 Part A|DRUG: NST-6179 Part B|OTHER: Matched Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intratumoral Injection of IP-001 Following Thermal Ablation in Patients With CRC, NSCLC, and STS
Status: RECRUITING
Conditions: Metastatic Solid Tumor|Colon Cancer|Nonsmall Cell Lung Cancer|Soft Tissue Sarcoma
Interventions: DRUG: 1.0% IP-001 for Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 3 Study to Evaluate WR 279,396 vs. Paromomycin Alone to Treat Cutaneous Leishmaniasis (in Tunisia)
Status: COMPLETED
Conditions: Cutaneous Leishmaniasis
Interventions: DRUG: WR 279,396 topical cream|DRUG: Paromomycin Alone topical cream|DRUG: Vehicle placebo cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Utilization and Efficacy of Tenofovir DF in Adolescents With Chronic Hepatitis B Virus Infection
Status: TERMINATED
Conditions: Hepatitis B
Interventions: DRUG: Tenofovir DF|RADIATION: DEXA Scan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study to Demonstrate Clinical Benefit of Lenalidomide and Dexamethasone
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: Lenalidomide|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A BCG Challenge Model Study to Assess Anti-mycobacterial Immunity Induced by BCG and a Candidate TB Vaccine, MVA85A
Status: COMPLETED
Conditions: Tuberculosis
Interventions: BIOLOGICAL: BCG: 100 microlitres ~ 2-8 x 105 pfu|BIOLOGICAL: MVA85A: 1 x 108 pfu BCG: 100 microlitres ~ 2-8 x 105 pfu
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effects Of PF-02545920 On Ketamine-Induced Abnormal Prefrontal Brain Response To Associative Learning In Healthy Subjects
Status: TERMINATED
Conditions: Healthy
Interventions: OTHER: Saline|DRUG: PF-02545920|OTHER: Ketamine|DRUG: PF-02545920|OTHER: Saline|OTHER: Placebo|OTHER: Ketamine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Naloxegol for the Prevention of Constipation in Postoperative Spinal Surgery Patients
Status: TERMINATED
Conditions: Constipation
Interventions: DRUG: MOVANTIK™ (naloxegol)|DRUG: Sugar Pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Immuno & Safety Study With 2 Formulations of DTPw-HBV/HIB When Given at Birth With Hepatitis B at 2, 4 and 6 Mths.Age.
Status: TERMINATED
Conditions: Haemophilus Influenzae Type b|Diphtheria|Tetanus|Hepatitis B|Whole Cell Pertussis
Interventions: BIOLOGICAL: Diphtheria, tetanus, pertussis, hepatitis B, Hib vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: A Phase 1 Study of ProMetic Plasminogen (Human) Intravenous in Adults and Children With Plasminogen Deficiency
Status: COMPLETED
Conditions: Type I Plasminogen Deficiency|Hypoplasminogenemia
Interventions: BIOLOGICAL: Plasminogen (Human) Intravenous
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Role of Hydrocortisone Either Alone or Combined With Fludrocortisone in the Outcome of Septic Shock in Adults
Status: COMPLETED
Conditions: Septic Shock
Interventions: DRUG: Hydrocortisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Study to Assess the Patterns of Use of REKOVELLE® in Naïve Women Undergoing In Vitro Fertilisation or Intracytoplasmic Sperm Injection Procedures
Status: COMPLETED
Conditions: Controlled Ovarian Stimulation
Interventions: DRUG: Follitropin Delta
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: MR-based Models for Clinically Significant Portal Hypertension in Cirrhosis (CHESS1802)
Status: COMPLETED
Conditions: Hypertension, Portal
Interventions: PROCEDURE: Transjugular HVPG measurement|PROCEDURE: MR imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study Intended to Evaluate Safety, Tolerability and Pharmacokinetics (PK) Parameters of BL-1021
Status: TERMINATED
Conditions: Healthy|Volunteers
Interventions: DRUG: BL-1021|DRUG: 1021
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Enhancing Quality of Life for Older Adults With and Without Mild Cognitive Impairment (MCI) Through Social Engagement Over Video Technology
Status: COMPLETED
Conditions: Aging|Mild Cognitive Impairment|Aging Well
Interventions: OTHER: OneClick Social Engagement Intervention|OTHER: OneClick Social Engagement Intervention Extension
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Safety and Efficacy of Immune Therapy for Condyloma
Status: UNKNOWN
Conditions: Condylomata Acuminata
Interventions: BIOLOGICAL: DC-CIK immunotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Stroke With Transfusions Changing to Hydroxyurea
Status: TERMINATED
Conditions: Hemochromatosis|Cerebrovascular Accident|Anemia, Sickle Cell|Hematologic Diseases
Interventions: PROCEDURE: Red Cell Transfusions|PROCEDURE: Iron Chelation|DRUG: Hydroxyurea|PROCEDURE: Phlebotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Therapeutic Effects of Compound Zhenzhu Tiaozhi Capsules in NAFLD
Status: UNKNOWN
Conditions: Nonalcoholic Fatty Liver Disease
Interventions: DIETARY_SUPPLEMENT: TLC|DRUG: metformin|DRUG: Compound Zhenzhu Tiaozhi capsule|DRUG: Simvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Compare Celecoxib and Ibuprofen Sr In The Management Of Acute Pain Post Orthopedic Or Gynecological Surgery
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: DRUG: celecoxib and ibuprofen SR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Assessing the Effect of DZD9008 on the Pharmacokinetics of the Cocktail Probes Representative for CYP3A4, P-gp, BCRP and OATP1B1 in Patients With EGFR or HER2 Mutant Advanced Non-small Cell Lung Cancer (WU-KONG19)
Status: RECRUITING
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: DZD9008 and Probe drugs (midazolam, digoxin, rosuvastatin)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigation of the Effectiveness of Electroacupuncture in Patients Undergoing Coronary Artery Bypass Surgery.
Status: RECRUITING
Conditions: Protective Effects of Acupuncture in Cardiac Surgery
Interventions: OTHER: acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Lidocaine as an Endotracheal Tube (ETT) Cuff Media
Status: COMPLETED
Conditions: Cardiac Disease
Interventions: DRUG: 1.8% lidocaine plus 0.76% sodium bicarbonate|OTHER: Air
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Combination Chemotherapy and Intensity-Modulated Radiation Therapy in Treating Patients Undergoing Surgery for Locally Advanced Rectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: capecitabine|DRUG: oxaliplatin|PROCEDURE: resection|RADIATION: radiation therapy|DRUG: FOLFOX
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Glidescope and Macintosh Laryngoscope for Double Lumen Endotracheal Tube Intubation
Status: COMPLETED
Conditions: Lung Disease
Interventions: DEVICE: GlideScope (GVL)|DEVICE: Macintosh Direct Laryngoscope (MDL)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy of Repeated Ketamine Infusions for Treatment-resistant Depression
Status: COMPLETED
Conditions: Treatment-resistant Depression
Interventions: DRUG: ketamine|DRUG: midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CisPlatin plUs Gemcitabine and Nabpaclitaxel (GAP) as pReoperative Chemotherapy Versus Immediate Resection in patIents With resecTable BiliarY Tract Cancers (BTC) at High Risk for Recurrence
Status: RECRUITING
Conditions: Biliary Tract Cancer|Cholangiocarcinoma
Interventions: DRUG: Gemcitabine|DRUG: Nab paclitaxel|DRUG: Cisplatin|PROCEDURE: Curative Surgery|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acute Study to Collect Electrical Signals From the Heart Using a Special Lead
Status: COMPLETED
Conditions: Tachycardia|Ventricular Arrhythmias
Interventions: DEVICE: Defibrillation following induction of VT/VF
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: |Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: "Dabrafenib and Trametinib in Circulating Free DNA BRAFV600 Mutated Metastatic Melanoma Patients: a Prospective Phase II, Open Label, Multicentre Study - (Bioliquid TAILOR Study - BIOTAILOR)"
Status: WITHDRAWN
Conditions: Melanoma
Interventions: DRUG: dabrafenib|DRUG: Trametinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bevacizumab, Docetaxel, and Carboplatin in Treating Women With Stage II or Stage III Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Avastin, docetaxel, carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Utility Of Genetic Screening For HLA-B*1301, On Susceptibility To Dapsone Hypersensitivity Syndrome
Status: UNKNOWN
Conditions: Allergic Cutaneous Vasculitis|Urticaria|Psoriasis|Acne|Bullous Skin Diseases|Sterile Pustulosis|Leprosy|Pneumocystis Pneumonia
Interventions: DRUG: Dapsone|GENETIC: HLA-B*1301
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Study of Response-Guided Duration of Combination Therapy With GS-9190, GS-9256, Pegasys® and Copegus® in Previously Untreated Subjects With Genotype 1 Chronic Hepatitis C
Status: COMPLETED
Conditions: Chronic Hepatitis C Infection
Interventions: DRUG: GS-9190|DRUG: GS-9256|BIOLOGICAL: Pegasys®|DRUG: Copegus®|DRUG: GS-9190 placebo|DRUG: GS-9256|BIOLOGICAL: Pegasys®|DRUG: Copegus®|DRUG: GS-9190 placebo|DRUG: GS-9256 placebo|BIOLOGICAL: Pegasys®|DRUG: Copegus®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Manual Therapy and Exercise With Mixed Reality With Hololens® Exercise Protocol in Chronic Neck Pain Patiens.
Status: TERMINATED
Conditions: Neck Pain|Chronic Pain
Interventions: OTHER: Manual Therapy and Usual care exercise protocol for neck pain|OTHER: Manual Therapy and Augmented reality exercise protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Contagious Misinformation Trial
Status: COMPLETED
Conditions: Misinformation
Interventions: BEHAVIORAL: Debunking Misinformation through Audio Dramas|BEHAVIORAL: Control group audio jingles
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Prospective, Double-Blind, Placebo-Controlled, Multicenter Study to Evaluate Efficacy and Safety of Atrasentan, Including Thoracic Bioimpedance, in Type 2 Diabetic Subjects With Nephropathy
Status: COMPLETED
Conditions: Chronic Kidney Disease|Diabetic Nephropathy
Interventions: DRUG: Atrasentan|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Brief Internet Intervention for Hazardous Alcohol Use to People Seeking Online Help for Depression
Status: COMPLETED
Conditions: Depression|Problem Drinking
Interventions: BEHAVIORAL: MoodGYM|BEHAVIORAL: Check Your Drinking
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The ELLIPSE Study: A Phase-1 Study Evaluating the Tolerance of Bevacizumab Nasal Spray to Treat Epistaxis in Hereditary Hemorrhagic Telangiectasia
Status: COMPLETED
Conditions: Rendu Osler Disease|Telangiectasia, Hereditary Hemorrhagic
Interventions: DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Liver Natural Killer Cell Therapy for Hepatoma Liver Transplantation
Status: COMPLETED
Conditions: Liver Cirrhosis|Hepatocellular Carcinoma|Evidence of Liver Transplantation
Interventions: BIOLOGICAL: Liver NK cell inoculation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Toffee Full Face and Toffee Nasal Mask Evaluation in Obesity Hypoventilation Syndrome (NZ)
Status: TERMINATED
Conditions: Obesity Hypoventilation Syndrome
Interventions: DEVICE: Toffee full face mask/toffee nasal mask
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A First-In Human (FIH) Trial to Find Out if REGN10597 is Safe and How Well it Works for Adult Participants With Advanced Solid Organ Malignancies
Status: NOT_YET_RECRUITING
Conditions: Melanoma|Clear-Cell Renal-Cell Carcinoma (ccRCC)|Advanced Solid Tumors
Interventions: DRUG: REGN10597
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study of SMOFlipid to Evaluate the Risk of Developing EFAD and/or PNAC in Pediatric and Adult Patients
Status: NOT_YET_RECRUITING
Conditions: Malnutrition, Child|Malnutrition
Interventions: DRUG: SMOFlipid® (lipid injectable emulsion)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Rollover Study for Subjects That Have Participated in an Astellas Sponsored Linsitinib Trial
Status: COMPLETED
Conditions: Advanced Solid Tumors
Interventions: DRUG: linsitinib|DRUG: erlotinib|DRUG: paclitaxel|DRUG: Bortezomib|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Exogenous Progesterone Free Luteal Phase After GnRHa Trigger - a Pilot Study in Normo-responder IVF Patients
Status: COMPLETED
Conditions: Infertility
Interventions: DRUG: hCG|DRUG: Progesterone and Estradiol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PENG Block for Total Hip Arthroplasty
Status: COMPLETED
Conditions: Hip Osteoarthritis|Hip Arthropathy|Hip Disease|Hip Pain Chronic
Interventions: DRUG: Ropivacaine 0.5% Injectable Solution|DRUG: 0,9% normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of a Red Rice and Olive Extract Nutrition Supplement on Cholesterol Levels in Patients With Metabolic Syndrome
Status: COMPLETED
Conditions: Hypercholesterolaemia
Interventions: DIETARY_SUPPLEMENT: commercially available nutrition supplement|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Gadobutrol Versus Gadopentetate Dimeglumine or Gadobenate Dimeglumine Before DCE-MRI in Diagnosing Patients With Multiple Sclerosis, Grade II-IV Glioma, or Brain Metastases
Status: TERMINATED
Conditions: Adult Anaplastic (Malignant) Meningioma|Adult Anaplastic Astrocytoma|Adult Anaplastic Ependymoma|Adult Anaplastic Oligodendroglioma|Adult Brain Stem Glioma|Adult Choroid Plexus Neoplasm|Adult Diffuse Astrocytoma|Adult Ependymoblastoma|Adult Ependymoma|Adult Giant Cell Glioblastoma|Adult Glioblastoma|Adult Gliosarcoma|Adult Grade II Meningioma|Adult Medulloblastoma|Adult Mixed Glioma|Adult Oligodendroglioma|Adult Papillary Meningioma|Adult Pineal Gland Astrocytoma|Adult Pineoblastoma|Adult Primary Melanocytic Lesion of Meninges|Adult Supratentorial Primitive Neuroectodermal Tumor|Malignant Adult Intracranial Hemangiopericytoma|Metastatic Malignant Neoplasm in the Brain|Multiple Sclerosis|Recurrent Adult Brain Neoplasm
Interventions: PROCEDURE: Dynamic Contrast-Enhanced Magnetic Resonance Imaging|DRUG: Gadobenate Dimeglumine|DRUG: Gadobutrol|RADIATION: Gadopentetate Dimeglumine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effect of Arrhythmia Surgery on Quality of Life in Patients With Atrial Fibrillation Undergoing Cardiac Surgery
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: PROCEDURE: Pulmonary vein isolation using microwave energy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: SCRT Sequential Penpulimab in Combination With CAPEOX in the Neoadjuvant Treatment of MSS Locally Advanced Rectal Cancer
Status: NOT_YET_RECRUITING
Conditions: Rectal Cancer|Locally Advanced
Interventions: RADIATION: Short-course radiotherapy|DRUG: Penpulimab|DRUG: CAPEOX|PROCEDURE: TME surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare Tablets and Capsules of Orforglipron (LY3502970) in Healthy Participants Who Are Obese or Overweight
Status: RECRUITING
Conditions: Healthy|Obese|Overweight|Obesity
Interventions: DRUG: Orforglipron
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect of Different Exercises on Lower Extremity Performance in Flexible Flatfoot
Status: ACTIVE_NOT_RECRUITING
Conditions: Flexible Flatfoot
Interventions: OTHER: PNF exercise|OTHER: Clam exercise|OTHER: Short-foot exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Doxorubicin-eluting-bead Embolization in Patients With Advanced Hepatocellular Carcinoma
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma
Interventions: PROCEDURE: Device(DC Bead)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use Of Valproid Acid To Treat Tropical Spastic Paraparesis/HTLV-1-Associated Myelopathy (TSP/HAM)
Status: COMPLETED
Conditions: Paraparesis Spastic Tropical
Interventions: DRUG: Valproic acid|DRUG: costicosteroids|DRUG: valproid acid plus corticosteroids
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing the Efficacy and Morbidity of Two Vertical Ridge Augmentation Techniques
Status: ACTIVE_NOT_RECRUITING
Conditions: Vertical Alveolar Bone Loss
Interventions: BIOLOGICAL: d-PTFE|BIOLOGICAL: Ti-mesh
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: FOLFOX6 as Neoadjuvant Chemotherapy in Local Advanced Gastric Cancer
Status: UNKNOWN
Conditions: Gastric Cancer|Effects of Chemotherapy|Surgery
Interventions: DRUG: mFOLFOX6 regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Crowdsourced Social Media Portal for Parents of Very Young Children With Type 1 Diabetes
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus
Interventions: BEHAVIORAL: Website
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Comparison Between the Intubating Laryngeal Tube Suction and the Ambu AuraGain
Status: COMPLETED
Conditions: Difficult Intubation
Interventions: DEVICE: Intubating Laryngeal Tube Suction|DEVICE: Ambu AuraGain Laryngeal Mask
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT