pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Imiquimod 5% Cream in Plaque-type Morphea: A Pilot, Prospective Open-label Study
Status: WITHDRAWN
Conditions: Morphea
Interventions: DRUG: imiquimod 5% cream (Aldara)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Image-Guided Adaptive Radiotherapy for in Detecting Tumors During Treatment in Patients With Head and Neck Cancer
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: PROCEDURE: computed tomography|PROCEDURE: cone-beam computed tomography|PROCEDURE: radiography|PROCEDURE: radiography|PROCEDURE: radiography|PROCEDURE: electronic portal imaging|RADIATION: image-guided adaptive radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of the Efficiency of Single Aligner Appliance for Treatment of Mild Crowding Cases in Adults.
Status: COMPLETED
Conditions: Crowding of Anterior Mandibular Teeth
Interventions: DEVICE: Modified aligner appliance|DEVICE: Traditional fixed appliance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Efficacy of Polybutester Suture on Postoperative Complications in Lower Impacted Third Molar Surgery
Status: COMPLETED
Conditions: Impacted Third Molar Tooth
Interventions: DEVICE: Polybutester suture|DEVICE: Polypropylene suture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Adbelimumab Combined With Chemotherapy and Apatinib in Patients With Resectable Esophageal Squamous Cell Carcinoma
Status: RECRUITING
Conditions: Esophageal Squamous Cell Carcinoma|Neoadjuvant Treatment
Interventions: DRUG: Adbelimumab, Albumin paclitaxel, Carboplatin, Apatinib|PROCEDURE: Esophagectomy|OTHER: Collecting samples from participant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Study to Assess the Effect of Severe Renal Impairment on the Pharmacokinetics, as Well as Safety/Tolerability, of Ranolazine
Status: TERMINATED
Conditions: Severe Renal Impairment
Interventions: DRUG: RANEXA
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nutritional Assessment Tool and Nutritional Intervention in Childhood Chronic Liver Disease
Status: COMPLETED
Conditions: Chronic Liver Disease
Interventions: DIETARY_SUPPLEMENT: Nutritional Supplement|DIETARY_SUPPLEMENT: Standard Nutritional Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Safety and Efficacy of GSK1278863 in Non-Dialysis Dependent (NDD) Subjects With Anemia Associated With Chronic Kidney Diseases (CKD)
Status: COMPLETED
Conditions: Anaemia
Interventions: DRUG: GSK1278863|DRUG: rhEPO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety of 6 Hours Feeding After Extracorporeal Shock Wave Lithotripsy of Pancreatic Stone
Status: NOT_YET_RECRUITING
Conditions: Pancreatic Duct Stone|ESWL|Fasting
Interventions: PROCEDURE: Early feeding group|PROCEDURE: Standard fasting group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Safety and Immunogenicity of H1N1 Vaccine With Trivalent Inactivated Seasonal Influenza Vaccine in Adults
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: GSK2340274A|BIOLOGICAL: GSK2340273A|BIOLOGICAL: Seasonal trivalent influenza vaccine (TIV)|BIOLOGICAL: Saline placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Manually Versus Digitally Fabricated Removable Partial Dentures
Status: COMPLETED
Conditions: Partially Edentulous Patients
Interventions: DEVICE: CAD/CAM fabricated RPD's|DEVICE: traditional fabricated RPD's
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Clinical Trial of NPI-0052 in Patients With Advanced Malignancies
Status: COMPLETED
Conditions: Advanced Cancer
Interventions: DRUG: NPI-0052 on Days 1, 8, 15 every 28 days|DRUG: NPI-0052 on Days 1, 4, 8, 11 every 21 days|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: D-Cycloserine Facilitation of Cocaine - Cue Extinction
Status: COMPLETED
Conditions: Cocaine Use Disorders
Interventions: DRUG: D-Cycloserine (DCS)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comprehensive Opioid Management in Patient Aligned Care Teams
Status: WITHDRAWN
Conditions: Chronic Pain
Interventions: BEHAVIORAL: IVR self-management|BEHAVIORAL: Opioid monitoring|OTHER: Enhanced usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety, Pharmacokinetics, and Pharmacokinetic of TQB3702 Tablets in Healthy Adult Subjects
Status: RECRUITING
Conditions: Systemic Lupus Erythematosus
Interventions: DRUG: TQB3702 tablets|DRUG: TQB3702 placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Safety and Tolerability of GDC-0349 in Patients With Locally Advanced or Metastatic Solid Tumors or Non Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Non-Hodgkin's Lymphoma, Solid Tumor
Interventions: DRUG: GDC-0349
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fecal Microbiota Transplantation in Irritable Bowel Syndrome With Bloating
Status: COMPLETED
Conditions: Irritable Bowel Syndrome
Interventions: PROCEDURE: FMT with donor stool|PROCEDURE: FMT with own stool
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PHOTOTHERAPY VERSUS PREGABALIN IN TREATMENT OF REFRACTORY UREAMIC PRURITIS
Status: UNKNOWN
Conditions: Refractory Uremic Pruritis
Interventions: DEVICE: NB UVB phototherapy|DRUG: Pregabalin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of BALI Association in the Treatment of Aphthous Ulcerations
Status: NOT_YET_RECRUITING
Conditions: Aphthous Stomatitis
Interventions: DRUG: BALI association|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Total Versus Subtotal Abdominal Hysterectomy at Time of Abdominal Sacrocolpopexy
Status: COMPLETED
Conditions: Prolapse Genital
Interventions: PROCEDURE: total abdominal hysterectomy|PROCEDURE: Subtotal abdominal hysterectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Retinal and Choriocapillary Vascular Changes in Patients Undergoing Tadalafil 20mg for More Than 6 Months
Status: COMPLETED
Conditions: Erectile Dysfunction Following Radical Prostatectomy
Interventions: DRUG: Tadalafil 20 MG
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Dexmedetomedine in Subtenon's Block on Emergence Agitation in Pediatric Strabismus Surgery
Status: COMPLETED
Conditions: Emergence Agitation
Interventions: DEVICE: Laryngeal Mask Airway|DRUG: Sevoflurane|PROCEDURE: Subtenon's Block|DRUG: Local Anesthetic Solution and Dexmedetomedine|DRUG: Local Anesthetic Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Efficacy of CDZ173 in Patients With APDS/PASLI
Status: COMPLETED
Conditions: Common Variable Immunodeficiency (CVID), APDS / PASLI
Interventions: DRUG: CDZ173|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Lixisenatide Compared to Liraglutide on the Postprandial Plasma Glucose in Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Lixisenatide (AVE0010)|DEVICE: Pen auto-injector|DRUG: Liraglutide|DEVICE: Pre-filled pen injector|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Is a Two-Film Skull X-ray Series as Sensitive as a Four-Film Series in the Diagnosis of Skull Fractures in Paediatric Patients
Status: COMPLETED
Conditions: Head Trauma
Interventions: OTHER: 4-views series|OTHER: 2-views serie
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy of Virtual Reality Exercises on Sarcopenia in Patients With Liver Transplantation
Status: NOT_YET_RECRUITING
Conditions: Sarcopenia
Interventions: OTHER: Virtual Reality exercise|OTHER: conventional treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pivotal Study to Assess the Efficacy, Safety and Tolerability of Dupilumab in Patients With Moderate to Severe COPD With Type 2 Inflammation
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Dupilumab SAR231893|DRUG: Inhaled Corticosteroid|DRUG: Inhaled Long-Acting Beta Agonist|DRUG: Inhaled Long-Acting Muscarinic Antagonist|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Investigate the Absorption, Metabolism, and Excretion of [14C]-GDC-9545 Following a Single Oral Dose (Part 1) and to Evaluate the Absolute and Relative Bioavailability of Oral Capsule Formulations of GDC-9545 (Part 2) in Healthy Female Subjects of Non-Childbearing Potential
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: [14C]-GDC-9545|DRUG: GDC-9545 Solution for Infusion|DRUG: GDC-9545/F12 Capsule|DRUG: GDC-9545/F18 Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Surgical Incision Closure Method to Prevent Niche Formation After Cesarean Section- Randomized Controlled Trial
Status: RECRUITING
Conditions: Cesarean Section Complications|Uterine Bleeding
Interventions: PROCEDURE: Niche prevention suture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Ketamine vs Lidocaine in Traumatic Rib Fractures
Status: RECRUITING
Conditions: Rib Fractures|Rib Fracture Multiple|Rib Trauma
Interventions: DRUG: Ketamine|DRUG: Lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Does Perineural Dexmedetomidine Prolong Duration of a Nerve Block?
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Dexmedetomidine|DRUG: Ropivacaine|DRUG: Isotonic Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Femoral Lengthening Might Impair Physical Function and Lead to Structural Changes in Adjacent Joints
Status: COMPLETED
Conditions: Leg Length Inequality|Leg; Lengthening|Osteoarthritis, Knee|Osteoarthritis of Hip|Quality of Life
Interventions: RADIATION: Radiographic imaging|OTHER: Evaluating function|OTHER: Forms
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Autologous Adipose Derived Mesenchymal Stem Cells for Spinal Cord Injury Patients
Status: RECRUITING
Conditions: Spinal Cord Injuries|Paralysis
Interventions: OTHER: Best Medical Management: Occupational and Physical Therapy|BIOLOGICAL: Autologous, Adipose Derived Mesenchymal Stem Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy in Treating Patients With Advanced Stomach Cancer
Status: COMPLETED
Conditions: Gastric Cancer
Interventions: DRUG: cisplatin|DRUG: docetaxel|DRUG: epirubicin hydrochloride|DRUG: fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Effect of Acetazolamide on Central Sleep Apnea Related to Opium Consumption
Status: UNKNOWN
Conditions: Central Sleep Apnea, Secondary
Interventions: DRUG: Acetazolamide-placebo|DRUG: Placebo-acetazolamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immunohistochemical Evaluation of Protein P16 Expression in Ovarian Germ Cell Tumors.
Status: COMPLETED
Conditions: Ovarian Neoplasms|Germ Cell Tumors|Immunohistochemistry
Interventions: COMBINATION_PRODUCT: p16INK4a Recombinant Rabbit Monoclonal Antibody (RM267)|COMBINATION_PRODUCT: Ki67 antibody (DAKO) for malignant cases only
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Longevity and Effectiveness of Bleaching in Healthy and Smokers Patients
Status: COMPLETED
Conditions: Dentin Sensitivity
Interventions: DRUG: Peroxide Carbamide 10% - Dental bleaching treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: RC48 Treatment for Platinum Sensitive Recurrent Ovarian Cancer With HER2 Expression
Status: RECRUITING
Conditions: Ovarian Carcinoma|Fallopian Tube Carcinoma|Primary Peritoneal Carcinoma
Interventions: DRUG: RC48+carboplatin±bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Open-label Extension Study of an Investigational Drug, Fitusiran, in Patients With Moderate or Severe Hemophilia A or B
Status: COMPLETED
Conditions: Hemophilia A|Hemophilia B
Interventions: DRUG: Fitusiran (SAR439774)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of MGd + High-dose MTX-Based Chemoimmunotherapy + RT for Newly Dx PCNSL
Status: WITHDRAWN
Conditions: Brain and Central Nervous System Tumors|Lymphoma|Neurotoxicity
Interventions: BIOLOGICAL: Rituximab|DRUG: Cytarabine|DRUG: Methotrexate|DRUG: Motexafin gadolinium|DRUG: Procarbazine hydrochloride|DRUG: Vincristine sulfate|RADIATION: Radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Prospective, Single-arm Clinical Study of Pabrolizumab in Combination With Cisplatin + 5-FU for the Neoadjuvant Treatment of Unresectable, Advanced Squamous Carcinoma of the Temporal Bone Single-arm Clinical Study
Status: RECRUITING
Conditions: Temporal Bone Squamous Cell Carcinoma
Interventions: DRUG: Paprizumab combined with cisplatin and 5-FU
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Flutter and PEP Mask on Chest Clearance, Dyspnea in Elderly Asthmatic Patients
Status: RECRUITING
Conditions: Asthma
Interventions: DEVICE: Flutter device|DEVICE: positive expiratory pressure mask
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Probiotics on Body Composition and Insulin Resistance in Patients With Obesity and Its Association With Gut Microbiota
Status: UNKNOWN
Conditions: Obesity|Insulin Resistance|Microbial Colonization
Interventions: DIETARY_SUPPLEMENT: Probiotics|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Role of Dietary Calcium for the Treatment of Osteopenia in Girls With Rett Syndrome
Status: COMPLETED
Conditions: Rett Syndrome
Interventions: DIETARY_SUPPLEMENT: calcium|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess BMS-986207 in Combination With Nivolumab and Ipilimumab as First-line Treatment for Participants With Stage IV Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: Nivolumab|DRUG: Ipilimumab|DRUG: BMS-986207|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial to Study if REGN5837 in Combination With Odronextamab is Safe for Participants With Aggressive B-cell Non-Hodgkin Lymphomas
Status: RECRUITING
Conditions: B-cell Non-Hodgkins Lymphoma (B-NHL)
Interventions: DRUG: Odronextamab|DRUG: REGN5837
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fasting Study of Verapamil HCl Extended-Release Capsules 300 mg and Verelan® PM Extended-Release Capsules 300 mg
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Verapamil HCL Extended-Release Capsules 300 mg|DRUG: Verelan® PM Extended-Release Capsules 300 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Effect of Propofol and Remifentanil Sequence on ED50 and ED95 of Rocuronium in Rapid Sequence Induction Anesthesia
Status: COMPLETED
Conditions: Anesthesia|Neuromuscular Blockade
Interventions: DRUG: Propofol|DRUG: Remifentanil|DRUG: Rocuronium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Effect of Non-Dissection of the Inferior Rectus Sheath on Intraoperative Blood Loss
Status: TERMINATED
Conditions: Acute Blood Loss Anemia|Postoperative Pain|Pregnancy
Interventions: PROCEDURE: non-dissection of inferior rectus sheath|PROCEDURE: control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Sequential Administration of Oral 6-Thioguanine (6-TG) After Methotrexate (MTX) in Patients With Relapsed Hodgkin's Disease (Phase II)
Status: COMPLETED
Conditions: Hodgkin's Disease
Interventions: DRUG: Methotrexate|DRUG: Leucovorin calcium|DRUG: 6-Thioguanine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acoustic Stimulation During Restricted Sleep After Sleep Deprivation
Status: RECRUITING
Conditions: Sleep Deprivation|Sleep Restriction|Acoustic Stimulation|Performance|Alertness
Interventions: DEVICE: Philips SmartSleep Acoustic Stimulation Device|DEVICE: Sham (no Acoustic Stimulation)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of 6 Week Hamstring Exercise Programs on Hamstring Muscle Function Performance in Female Athletes
Status: COMPLETED
Conditions: Hamstring Injury
Interventions: OTHER: Nordic hamstring exercise program|OTHER: Single leg bridge exercise program|OTHER: Hamstring razor curl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Clinical Performance of Self-cured Universal Adhesive for Restoring Cervical Lesions in Geriatric Patients
Status: UNKNOWN
Conditions: Universal Adhesive
Interventions: OTHER: universal adhesive|OTHER: universal adhesive
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fruquintinib in Combination With Sintilimab and CAPEOX as First-line Treatment for G/GEJ Cancer
Status: RECRUITING
Conditions: Metastatic Gastroesophageal Junction Adenocarcinoma
Interventions: DRUG: Fruquintinib in combination with Sintilimab and CAPEOX
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of MK-8655 in Participants With Type 2 Diabetes (MK-8655-002)
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: MK-8655|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Multitasking Rehabilitation She Enhanced Walking Speed Compared to the Simple Post Stroke Rehabilitation Task (AVC)?
Status: UNKNOWN
Conditions: Subacute Stroke
Interventions: OTHER: rehabilitation multitasking walking.|OTHER: Traditional walking rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating a Youth-Focused Economic Empowerment Approach to HIV Treatment Adherence
Status: ACTIVE_NOT_RECRUITING
Conditions: HIV
Interventions: BEHAVIORAL: Suubi+Adherence|BEHAVIORAL: Bolstered Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Nutrient Synergy in Beef and Stimulation of Protein Synthesis in Elderly
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: 3 ounces of cooked, 85% lean ground beef|DIETARY_SUPPLEMENT: 20 grams beef protein isolate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Dose Evaluation Safety STudy IN Individuals With Astrocytoma Taking PolyMVA
Status: COMPLETED
Conditions: Glioblastoma Multiform (Grade IV Astrocytoma)
Interventions: DRUG: PolyMVA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: External Beam Therapy With Theranostic Radioligand Therapy for Oligometastatic Prostate Cancer (ProstACT TARGET)
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Cancer
Interventions: BIOLOGICAL: 177Lu-DOTA-TLX591
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: M7824 and Topotecan or Temozolomide in Relapsed Small Cell Lung Cancers
Status: RECRUITING
Conditions: Carcinoma, Small Cell|Lung Cancer|Small Cell Lung Cancer
Interventions: DRUG: M7824|DRUG: Topotecan|DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Study of BAY1905254 - An Early Clinical Research Study to Evaluate a New Drug Called Bapotulimab (BAY1905254) in the Expansion Cohort in Combination With Pembrolizumab in Head and Neck Cancer That Has Returned or is Discovered to be Metastatic and is Expressing PDL1.
Status: COMPLETED
Conditions: Advanced Solid Tumor|Head and Neck Squamous Cell Carcinoma
Interventions: DRUG: Bapotulimab (BAY1905254)|DRUG: Bapotulimab (BAY1905254) + Pembrolizumab (KEYTRUDA®)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study Testing 1064nm Q-switch Laser Versus Glycolic Acid Peels for the Treatment of Melasma
Status: COMPLETED
Conditions: Melanosis
Interventions: DEVICE: 1064nm Q-switch Laser|OTHER: Glycolic Acid Peels
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Drug Interaction Study of Olmesartan in Healthy Chinese Volunteers
Status: COMPLETED
Conditions: Drug Interaction of Olmesartan in Healthy Chinese Volunteers
Interventions: DRUG: olmesartan medoxomil|DRUG: olmesartan medoxomil+probenecid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Implementation of an Enhanced Recovery After Surgery Program in Laparoscopic Roux-en-Y Gastric Bypass
Status: UNKNOWN
Conditions: Postoperative Pain
Interventions: COMBINATION_PRODUCT: ERAS protocol|COMBINATION_PRODUCT: Standard care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Pilot Study on Usefulness of Probe-based Confocal Laser Endomicroscopy Targeted Gastric Biopsy
Status: COMPLETED
Conditions: Gastric Cancer
Interventions: PROCEDURE: Probe-based confocal laser endomicroscopy|PROCEDURE: White light endoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Hydroxyurea Versus Aspirin and Hydroxyurea in Essential Thrombocythemia
Status: UNKNOWN
Conditions: MPN|Essential Thrombocythemia
Interventions: OTHER: Aspirin therapy interruption|OTHER: Usual treatment by aspirin 100 mg/d in the active comparator arm|OTHER: No interruption of aspirin in the Observational arm|DRUG: Hydroxyurea treatment (HU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of ABC008 for Inclusion Body Myositis
Status: ACTIVE_NOT_RECRUITING
Conditions: Inclusion Body Myositis
Interventions: DRUG: ABC008
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Idarubicin Based Combined Modality Therapy in Primary CNS Lymphoma
Status: COMPLETED
Conditions: Primary Central Nervous System Lymphoma
Interventions: DRUG: Idarubicin, Methotrexate, Filgrastim, intrathecal Ara-C|RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Clinical and Economic Impact of Pharmacogenomic Testing for Tamoxifen Metabolism in Postmenopausal Women Receiving Tamoxifen for Prevention of Recurrent Breast Cancer
Status: COMPLETED
Conditions: Breast Neoplasms|Tamoxifen
Interventions: OTHER: Poor Metabolism Status Follow Up Therapy Considerations|OTHER: CYP2D6 Inhibiting Drugs
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: iotaSOFT Pediatric Study
Status: RECRUITING
Conditions: Hearing Loss, Sensorineural|Hearing Loss, Bilateral|Hearing Loss, Unilateral
Interventions: DEVICE: iotaSOFT Insertion System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Time-Restricted Feeding on Glucose Homeostasis and Quality of Life
Status: UNKNOWN
Conditions: Diabetes Mellitus, Type 2|Time Restricted Feeding
Interventions: BEHAVIORAL: TRF|BEHAVIORAL: Normal timing of food intake
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, Pharmacokinetics and -Dynamics of Multiple Rising Oral Doses of BI 113823 in Patients Patients With Osteoarthritis of the Knee
Status: TERMINATED
Conditions: Osteoarthritis
Interventions: DRUG: BI 113823
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: The Nordic Aortic Valve Intervention Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Critical Aortic Stenosis
Interventions: PROCEDURE: Transcatheter Aortic Valve Implantation|PROCEDURE: Surgical Aortic Valve Replacement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Aqueous Cinnamon Extract on the Postprandial Glycaemia Levels in Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: OTHER: Placebo (OGTT)|OTHER: Cinnamon (OGTT plus aqueous cinnamon extract)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Cetuximab, Fluorouracil, and Pelvic Irradiation in Treating Patients With Locally Advanced or Locally Recurrent Rectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: BIOLOGICAL: cetuximab|DRUG: fluorouracil|PROCEDURE: neoadjuvant therapy|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hyperpolarized Noble Gas MR Imaging for Pulmonary Disorders
Status: TERMINATED
Conditions: COPD|Cystic Fibrosis|Asthma|Healthy
Interventions: DRUG: Hyperpolarized Helium-3
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation of Patients With Immune Function Abnormalities
Status: RECRUITING
Conditions: Chronic Granulomatous Disease (CGD)|X-Linked Severe Combined Immune Deficiency (XSCID)|Leukocyte Adhesion Deficiency 1 (LAD)|Graft Versus Host Disease (cGvHD)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of the Effect of RO4607381 on Atherosclerotic Plaque in Patients With Coronary Heart Disease
Status: COMPLETED
Conditions: Coronary Heart Disease
Interventions: DRUG: Dalcetrapib (RO4607381)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison Study on Topical Anesthetic Agents (LMX4 and BLT) Prior to Fractional Skin Resurfacing
Status: WITHDRAWN
Conditions: Pain
Interventions: DRUG: LMX4|DRUG: BLT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PET Imaging of Cyclooxygenases in Neurodegenerative Brain Disease
Status: RECRUITING
Conditions: Dementia|Alzheimer's Disease|ALS|Parkinson's Disease
Interventions: DRUG: 11C-MC1|DRUG: 11C-PS13|DRUG: 18f-florbetaben
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparison Between the SBK Microkeratome Versus Femtosecond Laser in Flap Creation During LASIK Surgery for Myopia
Status: COMPLETED
Conditions: Refractive Surgery
Interventions: DEVICE: SBK microkeratome versus femtosecond laser in flap creation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Novel Approaches to Reducing Tobacco Related Harm
Status: COMPLETED
Conditions: Smoking|Tobacco Smoking Behavior|Cigarette Smoking
Interventions: OTHER: Usual brand cigarettes|OTHER: Lower nicotine content cigarettes|OTHER: Electronic cigarettes 1|OTHER: Electronic cigarettes 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Impact of Correction of Vitamin D Deficiency in Oxidative Stress in Patients With Prediabetes (VICOX)
Status: TERMINATED
Conditions: Vitamin D Deficiency|Glucose Intolerance|Oxidative Stress|Insulin Resistance
Interventions: DRUG: Vitamin D|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Omega-3 Fatty Acids Supplementation on Brain and Behaviour in Healthy Children.
Status: COMPLETED
Conditions: Behaviour
Interventions: DIETARY_SUPPLEMENT: ω-3 LC-PUFA|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose:
Clinical trial: Gastric Bypass With Different Lengths of the Bilipancreatic Limb
Status: ACTIVE_NOT_RECRUITING
Conditions: Laparoscopic-Roux-en-Y Gastric Bypass|Obesity|Diabetes Mellitus, Type 2|Hypertension|Dyslipidemias|Sleep Apnea
Interventions: PROCEDURE: Roux-en-Y Gastric Bypass (RYGB) measuring the lengh of the common limb
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Respiratory Rehabilitation Exercises in Older Adults With Acute Exacerbations of Chronic Obstructive Pulmonary Disease
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: BEHAVIORAL: Respiratory rehabilitation exercise training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Defined Fecal Microbiota Transplantation for Clostridium Difficile Diarrhea
Status: ENROLLING_BY_INVITATION
Conditions: Active C. Difficile Colitis
Interventions: BIOLOGICAL: Microbiota Transplantation (FMT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Flos Gossypii Flavonoids Tablet in the Treatment of Alzheimer's Disease
Status: RECRUITING
Conditions: Alzheimer Disease
Interventions: DRUG: Flos gossypii flavonoids tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: To Evaluate the Safety and Efficacy of Acetaminophen 650 mg and 1000mg in Dental Pain After Surgery
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Acetaminophen|DRUG: Placebo Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Outcome of Second Generation Drug-eLuting Stents in Patients With Diabetes Mellitus
Status: WITHDRAWN
Conditions: Coronary Artery Disease|Diabetes Mellitus
Interventions: DEVICE: Taxus Element stent|DEVICE: Integrity Resolute stent|DEVICE: Xience Prime stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of LBR-101 In Chronic Migraine
Status: COMPLETED
Conditions: Chronic Migraine
Interventions: DRUG: LBR-101 High Dose|DRUG: LBR-101 Low Dose|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Characteristics of a Maxillofacial Prosthesis Consultation Within Assistance Publique - Hopitaux de Paris
Status: COMPLETED
Conditions: Head and Neck Neoplasm|Cleft Palate|Cleft Lip
Interventions: OTHER: Questionnaire
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: An Interactive Preventive Health Record (IPHR) to Promote Patient-Centered Preventive Care
Status: COMPLETED
Conditions: Prevention
Interventions: BEHAVIORAL: Interactive Preventive Health Record (IPHR)|BEHAVIORAL: "Standard" preventive care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Effectiveness and Safety of Flexible-dose Paliperidone Extended Release in Patients With Schizoaffective Disorder.
Status: COMPLETED
Conditions: Schizoaffective Disorder|Psychotic Disorder
Interventions: DRUG: Placebo|DRUG: Paliperidone ER|DRUG: Paliperidone ER
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Machine-Generated Mortality Estimates and Nudges to Promote Advance Care Planning Discussion Among Cancer Patients
Status: COMPLETED
Conditions: Oncology
Interventions: BEHAVIORAL: Nudge
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Postpregnancy Family Planning Choices in Public and Private Sectors in Kenya and Indonesia
Status: COMPLETED
Conditions: Post-pregnancy Family Planning|Capacity Building of Healthcare Providers
Interventions: BEHAVIORAL: PPFP Clinical and Counseling Skills|BEHAVIORAL: Facility-Level Leadership Management and Governance Training
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study to Evaluate the Pharmacokinetics of Abiraterone in Healthy Chinese Male Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Treatment A: abiraterone acetate|DRUG: Treatment B: abiraterone acetate|DRUG: Treatment C: abiraterone acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of NB1 Bone Graft Following Lumbar Interbody Arthrodesis
Status: RECRUITING
Conditions: Degenerative Disc Disease|Spondylolisthesis
Interventions: DEVICE: NB1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Oral Curcumin for Radiation Dermatitis
Status: COMPLETED
Conditions: Radiation-induced Dermatitis
Interventions: DRUG: Curcumin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Laser Acupuncture for Treating Monosymptomatic Nocturnal Enuresis in Adolescent Females
Status: RECRUITING
Conditions: Non-Specific Urethritis
Interventions: DEVICE: infrared (gallium aluminum arsenide laser)|DRUG: medical treatment(desmopressin acetate)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ESTxENDS Trial: MN Substudy - Micronuclei in Buccal Epithelium, a Surrogate Measure of Future Cancer Risk, Induced by Electronic Nicotine Delivery Systems (ENDS/Vaporizer/E-cig)
Status: COMPLETED
Conditions: Smoking Cessation|Micronuclei
Interventions: OTHER: ENDS (vaporizer/e-cig) and smoking cessation counseling|OTHER: Smoking cessation counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Omacetaxine + Azacitidine in Untreated Patients With High Grade MDS
Status: ACTIVE_NOT_RECRUITING
Conditions: High Grade Myelodysplastic Syndromes
Interventions: DRUG: Omacetaxine|DRUG: Azacitidine|DRUG: Omacetaxine|DRUG: Azacitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Solifenacin Succinate Versus Tolterodine 4mg Once Daily
Status: COMPLETED
Conditions: Urinary Bladder, Overactive
Interventions: DRUG: Solifenacin succinate|DRUG: Tolterodine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Non-surgical Periodontal Treatment on Oxidative Stress and Antioxidant Status in OSAS
Status: COMPLETED
Conditions: Periodontitis|Obstructive Sleep Apnea|OSAS
Interventions: OTHER: Experimental|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of IBI302 in Subjects With nAMD
Status: RECRUITING
Conditions: Neovascular Age-related Macular Degeneration
Interventions: DRUG: Aflibercept Ophthalmic|BIOLOGICAL: IBI302
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Isotonic Versus Hypotonic Fluid for Maintenance IV Therapy
Status: COMPLETED
Conditions: Gastroenteritis|Bronchiolitis|Sepsis|Urinary Tract Infection
Interventions: DRUG: 0.9% saline in 5% dextrose (intravenous)|DRUG: 0.45% saline in 5% dextrose (intravenous)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Safety and Scar Prevention Study of a Topical Antifibrotic Compound FS2.
Status: UNKNOWN
Conditions: Scar|Cicatrix|Hypertrophic Scar|Skin Graft Scar|Skin Graft Complications|Donor Site Complication|Keloid
Interventions: DRUG: Fibrosis-Inhibiting-Compound-FS2|OTHER: Vehicle moisture balancing base
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Fermentable Carbohydrate on Glucose Homeostasis
Status: COMPLETED
Conditions: Prediabetes
Interventions: DIETARY_SUPPLEMENT: Inulin|DIETARY_SUPPLEMENT: Cellulose|DIETARY_SUPPLEMENT: Inulin|DIETARY_SUPPLEMENT: Cellulose|DIETARY_SUPPLEMENT: Inulin|DIETARY_SUPPLEMENT: Cellulose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Clinical Trial to Evaluate the Pharmacokinetics and Safety of SIPS-2209-1 in Healthy Korean Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: SIPS-2209-1|DRUG: SIPS-2209-2, SIPS-2209-3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bonding, Self-effıcacy and Vital Signs in Infants Undergoing Cardiovascular Surgery
Status: ACTIVE_NOT_RECRUITING
Conditions: Mother-Infant Interaction
Interventions: OTHER: infant massage practice|OTHER: Safe Swaddling|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Visual Outcome in Patients With Symptomatic Macular Polypoidal Choroidal Vasculopathy (PCV) Treated With Either Ranibizumab as Monotherapy or Combined With Verteporfin Photodynamic Therapy (vPDT)
Status: COMPLETED
Conditions: Age-related Macular Degeneration|Polypoidal Choroidal Vasculopathy
Interventions: DRUG: Ranibizumab|DRUG: Verteporfin PDT|DRUG: Sham PDT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Safety and Immunogenicity Study of Inactivated SARS-CoV-2 Vaccine (Vero Cells) in Healthy Population Aged 18 Years and Above(COVID-19)
Status: UNKNOWN
Conditions: COVID-19
Interventions: BIOLOGICAL: medium dosage inactivated SARS-CoV-2 vaccine|BIOLOGICAL: high dosage inactivated SARS-CoV-2 vaccine|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: DTG Plus 3TC for Prophylaxis of Mother-to-child Transmission of HIV Infection in Pregnant Women
Status: COMPLETED
Conditions: HIV Infections|Pregnancy Related|Mother to Child Transmission
Interventions: DRUG: Dolutegravir plus lamivudine in a FDC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial to Assess the Elixir Medical LithiX Coronary Hertzian Contact Intravascular Lithotripsy Catheter
Status: ACTIVE_NOT_RECRUITING
Conditions: Coronary Artery Disease
Interventions: DEVICE: LithiX Coronary Hertzian Contact Intravascular Lithotripsy Catheter (LithiX Coronary HCIVLC; LithiX)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Memantine in Pediatric Patients With Autism, Asperger's Disorder or Pervasive Developmental Disorder Not Otherwise Specified (PDD-NOS)
Status: TERMINATED
Conditions: Autism Spectrum Disorder (ASD)|Autism|Autistic Disorder|Asperger's Disorder|Asperger's|Pediatric Autism|Pervasive Developmental Disorder Not Otherwise Specified (PDD-NOS)
Interventions: DRUG: Memantine Hydrochloride (HCl)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT