pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Dasatinib Added to Gemcitabine for Subjects With Locally-advanced Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DRUG: dasatinib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: AcuSleep in Mild Traumatic Brain Injury (TBI)
Status: COMPLETED
Conditions: Brain Injuries, Traumatic|Sleeplessness
Interventions: OTHER: Acupuncture|OTHER: Sham Acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Exercise on Cognition and Preventing Depression in Young People
Status: COMPLETED
Conditions: Subthreshold Depression|Exercise|Clinically-well|Cognitive Change
Interventions: BEHAVIORAL: Aerobic exercise intervention|BEHAVIORAL: Psycho-education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Cromolyn Sodium for Treatment of COVID-19 Pneumonia
Status: RECRUITING
Conditions: COVID-19 Pneumonia|COVID-19 Respiratory Infection|Pneumonia, Viral
Interventions: DRUG: Cromolyn Sodium|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Topical PlexoZome® Levagen® Spray on Relief of Post Exercise Knee Joint Pain
Status: NOT_YET_RECRUITING
Conditions: Knee Joint Pain
Interventions: DRUG: PlexoZome® Levagen® topical spray solution|DRUG: Placebo topical spray solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Global Network Implementation of Helping Babies Breathe (HBB)
Status: COMPLETED
Conditions: Perinatal Mortality
Interventions: BEHAVIORAL: HBB/ENC Training and Equipment|OTHER: HBB/ENC supplies
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effect of Crestor on Lipoprotein Metabolism in Humans
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DRUG: Rosuvastatin at 5 mg/day and 40 mg/day
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non--operative Treatment of the Medial Malleolus in bi- and Trimalleolar Ankle Fractures
Status: COMPLETED
Conditions: Ankle Malleolus Fracture Bimalleolar|Fracture of Medial Malleolus|Fracture of Ankle
Interventions: PROCEDURE: Internal fixation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pemetrexed Disodium in Treating Patients With Previously Treated Metastatic Urothelial Cancer
Status: TERMINATED
Conditions: Metastatic Urothelial Carcinoma
Interventions: OTHER: Laboratory Biomarker Analysis|DRUG: Pemetrexed Disodium
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Prevent Radiation Induced Damage to Bowel Using a Prebiotic Enhanced Diet.
Status: UNKNOWN
Conditions: Radiation Enteritis|Radiation Proctitis
Interventions: DIETARY_SUPPLEMENT: FructoOligoSaccharide|DIETARY_SUPPLEMENT: Maltodextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: ERCP in Idiopathic Recurrent Acute Pancreatitis
Status: COMPLETED
Conditions: Recurrent Acute Pancreatitis
Interventions: PROCEDURE: Biliary sphincterotomy|PROCEDURE: Pancreatobiliary sphincterotomy|PROCEDURE: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized, Unicentric, Open, Controlled Clinical Trial, in Phase Iii, to Demonstrate the Effectiveness of Tocilizumab
Status: UNKNOWN
Conditions: COVID-19 Pneumonia
Interventions: DRUG: Tociliziumab group|DRUG: Methylprednisolone group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Targeting Specific Brain Networks to Treat Specific Symptoms in Depression
Status: RECRUITING
Conditions: Major Depressive Disorder
Interventions: DEVICE: Intermittent Theta Burst Stimulation (iTBS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Comparison of Contact-force Monitoring Irrigated Tip Catheter and Mesh-like Irrigated Tip Catheter in Atrial Fibrillation Ablation: Prospective Randomized Trial (COMMIC Trial)
Status: UNKNOWN
Conditions: Atrial Fibrillation
Interventions: PROCEDURE: FlexAbility (Mesh-like irrigated tip catheter) group|PROCEDURE: TactiCath (Contract force monitoring catheter) group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of a New Abbott Medical Optics (AMO) Multi-Purpose Solution (MPS) to Existing Contact Lens Regimens
Status: COMPLETED
Conditions: Normal Contact Lens Wearers
Interventions: DEVICE: Multi-purpose disinfecting solution|DEVICE: Clear Care|DEVICE: Opti-Free RepleniSH
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Phase II Axitinib (AG-013736) in Elderly Glioblastoma Multiforme (GBM) Patients
Status: TERMINATED
Conditions: Glioblastoma Multiforme
Interventions: DRUG: Axitinib|RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gemcitabine and Oxaliplatin in Treating Patients With Locally Advanced or Metastatic Pancreatic Cancer
Status: UNKNOWN
Conditions: Pancreatic Cancer
Interventions: DRUG: gemcitabine hydrochloride|DRUG: oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: The Stool Microbiome of Treated and Untreated IBS (Irritable Bowel Syndrome) Patients
Status: RECRUITING
Conditions: Irritable Bowel Syndrome
Interventions: OTHER: Low FODMAP dietary regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: EBV-TCR-T Cells for EB Virus Infection After HSCT
Status: COMPLETED
Conditions: EBV Emia and EBV Positive PTLD After Allogenic HSCT
Interventions: BIOLOGICAL: EBV-TCR-T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, PK and Efficacy of QXL138AM in Patients With Solid Tumors and Multiple Myeloma
Status: RECRUITING
Conditions: Ovarian Cancer|Pancreas Cancer|Urothelial Carcinoma|Renal Cell Carcinoma|Hepatocellular Carcinoma|Gastrointestinal Cancer|Lung Cancer|Prostate Cancer|Breast Cancer
Interventions: BIOLOGICAL: QXL138AM Injection every 2 weeks by IV Infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: VolulyteTM in Cardiac Surgery
Status: COMPLETED
Conditions: Heart; Dysfunction Postoperative, Cardiac Surgery
Interventions: DRUG: 6% hydroxyethyl starch 130/0.4 in an isotonic electrolyte solution (VolulyteTM)|DRUG: Human serum albumin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Meta-analysis of Stannous Fluoride Dentifrice and the Effects on Dentine Hypersensitivity
Status: COMPLETED
Conditions: Dentine Hypersensitivity
Interventions: DRUG: Stannous fluoride dentifrice|DRUG: Positive control dentifrice|DRUG: Negative control dentifrice
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison Between Transvaginal Mesh and Traditional Surgery for Pelvic Organ Prolapse
Status: COMPLETED
Conditions: Vaginal Prolapse
Interventions: PROCEDURE: Anterior colporrhaphy|PROCEDURE: Anterior PROLIFT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Immunological Evaluation of Telitacicept and Low Dose IL2 in the Treatment of Systemic Lupus Erythematosus
Status: RECRUITING
Conditions: Systemic Lupus Erythematosus
Interventions: DRUG: Telitacicept|DRUG: Interleukin-2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Pharmacokinetics of ODM-204 in Patients With Metastatic Castration-Resistant Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: ODM-204|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Entecavir Plus Adefovir in Lamivudine-Resistant Chronic Hepatitis B Patients Who Fail Lamivudine Plus Adefovir
Status: COMPLETED
Conditions: Hepatitis B, Chronic
Interventions: DRUG: Adefovir|DRUG: Entecavir|DRUG: Lamivudine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pivotal Subjective Sleep Study of a Nasal Dilator (Breathe Right Tan)
Status: COMPLETED
Conditions: Congestion, Nasal
Interventions: DEVICE: Breathe Right Tan (small/medium) nasal strips|OTHER: Placebo nasal strip
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Role of Endothelin in the Supine Hypertension of Autonomic Failure
Status: WITHDRAWN
Conditions: Hypertension|Pure Autonomic Failure|Multiple System Atrophy
Interventions: DRUG: BQ123|DRUG: BQ123|DRUG: Bq123|DRUG: BQ123|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Integrating Palliative Care for Patients With Idiopathic Pulmonary Fibrosis and Their Caregivers
Status: COMPLETED
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: OTHER: SUPPORT|OTHER: Currently Available Printed Material
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Bronchoscopic Score for Prediction of Herpes Simplex-virus Type 1 (HSV-1) Reactivation
Status: RECRUITING
Conditions: Tracheobronchitis|Herpes Simplex Infection
Interventions: DIAGNOSTIC_TEST: Patients with herpes-simplex infection requiring bronchoscopy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Diagnosis and Treatment of Patients With Femoroacetabular Impingement Syndrome
Status: UNKNOWN
Conditions: Femoroacetabular Impingement
Interventions: OTHER: Physiotherapist-led treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Creating a Proficiency-Based Virtual Reality Simulation Training Programme for Laparoscopic Assisted Colectomy
Status: UNKNOWN
Conditions: Colorectal Disease
Interventions: OTHER: Proficiency-based virtual reality simulation training|OTHER: Training under the current surgical training programme
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Study Assessing Utility of a Clinical Questionnaire to Identify Subjects With Features of Both Asthma and Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: PROCEDURE: Spirometry|OTHER: ACOS clinical questionnaire
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Horizontal Ridge Augmentation in Mandible Usign ROG + ESWT
Status: COMPLETED
Conditions: Bone Regeneration
Interventions: PROCEDURE: ROG|PROCEDURE: ROG & ESWT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Study of TTX-030 and Chemotherapy With or Without Budigalimab for 1L mPDAC Patients
Status: RECRUITING
Conditions: Pancreatic Cancer
Interventions: COMBINATION_PRODUCT: TTX-030, nab-paclitaxel and gemcitabine|COMBINATION_PRODUCT: TTX-030, budigalimab, nab-paclitaxel and gemcitabine|COMBINATION_PRODUCT: Nab-Paclitaxel and gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of High-Dose Quadrivalent Influenza Vaccine in Patients ≥65 Years
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: QIV-HD by IM|BIOLOGICAL: QIV-SD by SC|BIOLOGICAL: QIV-HD by SC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Peri-operative Immunonutrition on Recurrence and Infections in Crohn's Disease Patients
Status: UNKNOWN
Conditions: Crohn Disease
Interventions: OTHER: Standard of Care|DIETARY_SUPPLEMENT: Immunonutrition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effects of the Direct Acting Antiviral Agent Boceprevir on the Pharmacokinetics of Maraviroc in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Maraviroc (5 days)|DRUG: Maraviroc and boceprevir (14 days)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: FUS-TB VS COG-TB in Small Lesions of Prostate Cancer
Status: NOT_YET_RECRUITING
Conditions: Prostate Cancer
Interventions: PROCEDURE: COG-TB: Cognitive Fusion guided prostate targeted Biopsy|PROCEDURE: FUS-TB: MRI-TRUS Fusion guided prostate targeted Biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Use of Pulsed Low-dose Rate Re-irradiation for Recurrent Glioma (PULSAR)
Status: RECRUITING
Conditions: Glioma
Interventions: RADIATION: Pulsed low dose-rate radiotherapy (pLDRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GNOS-PV02 Personalized Neoantigen Vaccine, INO-9012 and Pembrolizumab in Subjects With Advanced HCC
Status: ACTIVE_NOT_RECRUITING
Conditions: HCC
Interventions: BIOLOGICAL: GNOS-PV02|BIOLOGICAL: INO-9012|DRUG: Pembrolizumab|DEVICE: CELLECTRA®2000 EP Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Apremilast to Treat Active Ulcerative Colitis
Status: COMPLETED
Conditions: Ulcerative Colitis
Interventions: DRUG: Apremilast|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Compare PK & Safety of Advixa With Humira in Healthy, Adult Subject Followed by Efficacy & Safety Study in RA Patients
Status: UNKNOWN
Conditions: Pharmacokinetics|Safety|Efficacy|Rheumatoid Arthritis
Interventions: DRUG: Advixa (Adalimumab)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Discovery of Arthritis in Psoriasis Patients for Early Rheumatological Referral
Status: COMPLETED
Conditions: Psoriasis|Psoriatic Arthritis|Psoriasis Vulgaris|Psoriatic Nail
Interventions: OTHER: cutaneous parameters of psoriasis (exposure)|OTHER: comorbidity (exposure)|OTHER: family history (exposure)|OTHER: lifestyle (exposure)|OTHER: patient reported outcomes (exposure)|OTHER: inflammatory markers (exposure)|OTHER: genetic (exposure)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase I Study to Assess the Safety and Distribution of VB-111 in Patients With Advanced Metastatic Cancer
Status: UNKNOWN
Conditions: Advanced and/or Metastatic Solid Organ Cancer
Interventions: DRUG: VB-111
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigating the Safety and Effectiveness of Insulin Degludec in a Real World Population With Type 1 and 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 1|Diabetes Mellitus, Type 2
Interventions: DRUG: insulin degludec
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Levamisole and Isoprinosine in the Treatment of COVID19: A Proposed Therapeutic Trial
Status: UNKNOWN
Conditions: Respiratory Tract Infections
Interventions: DRUG: Levamisole and isoprinosine|DRUG: Azithromycin and hydroxychloroquine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of Montelukast for Treatment of Acute Bronchiolitis
Status: COMPLETED
Conditions: Bronchiolitis
Interventions: DRUG: montelukast sodium|OTHER: sucrose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of One Dose of Seasonal Trivalent Influenza Virus Vaccine (TIVf, Purified Surface Antigen, Inactivated, Egg Derived) in Adults, Aged 18 Years and Above
Status: COMPLETED
Conditions: Human Influenza
Interventions: BIOLOGICAL: TIVf
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Analysis of Genetic and Environmental Parameters Influencing Growth Rate of Precocious Puberty Children
Status: UNKNOWN
Conditions: Central Precocious Puberty
Interventions: DRUG: Triptorelin (GnRH agonists)|DRUG: Leuprolide (GnRH agonists)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Exploration of Neural Bases in Social Cognition
Status: UNKNOWN
Conditions: Interpersonal Relations|Schizophrenia|Magnetic Resonance Imaging, Functional
Interventions: OTHER: fMRI social cognition task
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Prospective/Retrospective,Randomized Controlled Clinical Study of Antiviral Therapy in the 2019-nCoV Pneumonia
Status: UNKNOWN
Conditions: 2019-nCoV
Interventions: DRUG: Abidol hydrochloride|DRUG: Oseltamivir|DRUG: Lopinavir/ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effects of Carnitine Supplementation on Liver and Muscle
Status: COMPLETED
Conditions: Non-Alcoholic Fatty Liver Disease|Insulin Resistance
Interventions: DIETARY_SUPPLEMENT: L-Carnitine tartrate|DIETARY_SUPPLEMENT: Meal Replacement Drink|DIETARY_SUPPLEMENT: Maltodextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Clinical Study of the TriVascular Ovation™ Abdominal Stent Graft System
Status: COMPLETED
Conditions: Aortic Aneurysm, Abdominal
Interventions: DEVICE: Ovation™ Abdominal Stent Graft System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of HuMab-5B1 (MVT-5873) in Subjects With Pancreatic Cancer or Other Cancer Antigen 19-9 (CA19-9) Positive Malignancies
Status: ACTIVE_NOT_RECRUITING
Conditions: Pancreatic Cancer
Interventions: DRUG: MVT-5873|DRUG: modified FOLFIRINOX (mFOLFIRINOX)|DRUG: gemcitabine + nab-paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Acute Effect of Statins on Inflammatory Markers of Athersclerotic Tissue
Status: COMPLETED
Conditions: Carotid Artery Disease
Interventions: DRUG: simvastatin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hepato Biliary Scintigraphy to Assess the Risk of Postoperative Liver Failure Hepatectomies
Status: UNKNOWN
Conditions: Hepatic Insufficiency
Interventions: DEVICE: Hepatobiliary scintigraphy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: A Single and Multiple Dose Study of PF-05221304 in Healthy Japanese Adults
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: PF-05221304|DRUG: PF-05221304|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Longitudinal Changes in Achilles Tendon and Medial Gastrocnemius Muscle Architecture During a 156-km Ultradistance Trail Running Event
Status: COMPLETED
Conditions: Achilles Tendinopathy|Calf Injury|Sport Injury|Lower Limb Injury
Interventions: DIAGNOSTIC_TEST: Ultrasound measurement of triceps surae muscle-tendon architecture
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Confirmatory Trial for Alleviating Fatigue in Multiple Sclerosis
Status: NOT_YET_RECRUITING
Conditions: Multiple Sclerosis|Fatigue
Interventions: DEVICE: Online Therapy for Fatigue
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Exercise and Probiotics on Dysmenorrhea and Microbiome
Status: UNKNOWN
Conditions: Dysmenorrhea|Inflammation|Microbial Substitution
Interventions: OTHER: Aerobic exercise|OTHER: Resistant exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: VESIcare For Improving OAB Symptoms in Patients Undergoing IGRT of the Prostate
Status: TERMINATED
Conditions: Over-Active Bladder
Interventions: DRUG: Solifenacin succinate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Biofilm Accumulation in Zirconia vs. Titanium Implants
Status: RECRUITING
Conditions: Implant Infection
Interventions: PROCEDURE: dental implant placement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Acupuncture for Oligomenorrhea Due to Polycystic Ovary Syndrome
Status: UNKNOWN
Conditions: Polycystic Ovary Syndrome|Oligomenorrhea
Interventions: DEVICE: Acupuncture+Usual care|BEHAVIORAL: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ibrutinib and PD-1 Blockade in High Risk Lymphocytic Leukemia
Status: TERMINATED
Conditions: Chronic Lymphocytic Leukemia
Interventions: DRUG: Pembrolizumab|DRUG: Ibrutinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Metoprolol in Acute Respiratory Distress Syndrome (MAIDEN)
Status: NOT_YET_RECRUITING
Conditions: Acute Respiratory Distress Syndrome (ARDS)
Interventions: DRUG: Metoprolol Injection|DRUG: saline 0.9%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness and Safety of Epivir/Ziagen/Zerit (3TC/ABC/d4T) Versus Epivir/Ziagen/Sustiva (3TC/ABC/EFV) Versus Epivir/Ziagen/Agenerase/Norvir (3TC/ABC/APV/RTV) in HIV Patients Who Have Never Received Treatment
Status: UNKNOWN
Conditions: HIV Infections
Interventions: DRUG: Ritonavir|DRUG: Abacavir sulfate|DRUG: Amprenavir|DRUG: Efavirenz|DRUG: Lamivudine|DRUG: Stavudine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Denosumab vs Zoledronic Acid and Osteoporotic Compression Fracture
Status: RECRUITING
Conditions: Denosumab vs Zoledronate
Interventions: DRUG: Denosumab|DRUG: Zoledronic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Angiogenesis Using VEGF-A165/bFGF Plasmid Delivered Percutaneously in No-option CAD Patients; a Controlled Trial
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: GENETIC: intramyocardial injection of VEGF-A165/bFGF:placebo plasmid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Clinical Trial to Evaluate the Efficacy of Bevacizumab for Renal Cell Carcinoma
Status: COMPLETED
Conditions: Renal Cell Carcinoma|Kidney Cancer
Interventions: DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Peri-Operative Magnesium Infusion to Prevent Atrial Fibrillation Evaluated.
Status: TERMINATED
Conditions: Atrial Fibrillation New Onset
Interventions: DRUG: Magnesium sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Preemptive Tapentadol on Post-operative Analgesia Following Total Knee Arthroplasty
Status: COMPLETED
Conditions: Analgesia
Interventions: DRUG: Tapentadol 100 MG|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Role of Maintaining External Carotid Artery Flow in Graft Interposition After Carotid Endarterectomy
Status: RECRUITING
Conditions: Carotid Artery Diseases|Stroke|Carotid Atherosclerosis
Interventions: PROCEDURE: Carotid graft interposition
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Casting Versus Flexible Intramedullary Nailing in Displaced Pediatric Forearm Shaft Fractures
Status: RECRUITING
Conditions: Both Bone Forearm Fracture|AO Classification 22D/2.1-5.2|7-12 Year Old
Interventions: PROCEDURE: Flexible intramedullary nail (FIN)|PROCEDURE: Reduction auder general anesthesia and long arm cast
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Resveratrol in Type2 Diabetes and Obesity
Status: TERMINATED
Conditions: Type 2 Diabetes|Obesity|Insulin Resistance
Interventions: DRUG: Placebo|DRUG: Resveratrol 40 mg oral three times a day|DRUG: Resveratrol 500 mg oral once daily.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: RTI-336 as a Treatment for Methamphetamine Dependence
Status: WITHDRAWN
Conditions: Methamphetamine Dependence|Substance Abuse|Methamphetamine Abuse
Interventions: DRUG: RTI-336|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Can High Intensity Inspiratory Muscle Training Improve Inspiratory Muscle Strength and Accelerate Weaning in Medical Patients With Difficulty on Weaning?
Status: UNKNOWN
Conditions: Weaning Failure
Interventions: PROCEDURE: Low Intensity IMT|PROCEDURE: High Intensity IMT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Follow-up Yttrium-90 Internal Pair Production PET/CT vs Brehmsstrahlung Imaging in Patients With Primary/Metastatic Liver Tumors
Status: COMPLETED
Conditions: Liver Cancer|Hepatic Tumors
Interventions: DEVICE: PET/CT Scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Thoracic Drains in Intensive Care Units: Comparison of Seldinger and Surgical Methods
Status: COMPLETED
Conditions: Pleural Effusion|Pneumothorax|Hemothorax
Interventions: PROCEDURE: Pleural drainage procedure with Seldinger procedure|PROCEDURE: Pleural drainage procedure with surgical-like technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigating Hearing Aid Frequency Response Curves 2
Status: COMPLETED
Conditions: Hearing Loss, Sensorineural|Hearing Loss, Bilateral
Interventions: DEVICE: Hearing Aid - Standard Curve|DEVICE: Hearing Aid - Variation #1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of HSK16149 Capsule in the Treatment of Moderate and Severe Central Neuropathic Pain in China
Status: NOT_YET_RECRUITING
Conditions: Central Neuropathic Pain
Interventions: DRUG: HSK16149 20mg-40mg BID|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Social Media and Breastfeeding Self Efficacy
Status: COMPLETED
Conditions: Breastfeeding
Interventions: OTHER: Breastfeeding education and counseling|OTHER: Routine postpartum breastfeeding training included in the hospital procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Improvement of Outcomes in Draf III/Endoscopic Modified Lothrop Procedure
Status: WITHDRAWN
Conditions: Chronic Sinusitis|Frontal Sinusitis
Interventions: DEVICE: Porcine Intestinal submucosal xenograft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Metabolic Response to Reduced Branched-chain Amino Acids in Humans
Status: COMPLETED
Conditions: Diabetes|Obesity|Insulin Resistance
Interventions: OTHER: Whey protein powder|OTHER: BCAD2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Xylometazoline and Cocaine for Nasal Vasoconstriction
Status: COMPLETED
Conditions: Epistaxis
Interventions: DRUG: Xylometazoline 0,1%|DRUG: Cocaine 4%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Osteosarcoma Study #2: A Randomized Trial of Pre-Surgical Chemotherapy vs. Immediate Surgery and Adjuvant Chemotherapy in the Treatment of Non-Metastatic Osteosarcoma. A Pediatric Oncology Group Phase III Study
Status: COMPLETED
Conditions: Osteosarcoma
Interventions: DRUG: pre-surgical chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Rhinovirus Study With Lactobacillus Rhamnosus GG
Status: COMPLETED
Conditions: Respiratory Tract Infections [C08.730]
Interventions: OTHER: Fruit juice with Lactobacillus rhamnosus GG, version 1|OTHER: Fruit juice with Lactobacillus rhamnosus GG, version 2|OTHER: Standard fruit juice
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose:
Clinical trial: Study of Gabapentin Extended Release (G-ER) in the Treatment of Vasomotor (Hot Flashes/Hot Flushes) Symptoms in Postmenopausal Women
Status: COMPLETED
Conditions: Hot Flashes
Interventions: DRUG: Gabapentin Extended-Release (G-ER) 1200 mg|DRUG: Gabapentin Extended-Release (G-ER) 1800 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1/2 Study of DCC-3116 in Patients With RAS/MAPK Pathway Mutant Solid Tumors
Status: RECRUITING
Conditions: Non-Small Cell Lung Cancer|Advanced Solid Tumor|Metastatic Solid Tumor
Interventions: DRUG: DCC-3116|DRUG: Trametinib|DRUG: Binimetinib|DRUG: Sotorasib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Assess Efficacy, Tolerability of Rising Doses of Clodronate in Painful Knee Osteoarthritis Patients
Status: RECRUITING
Conditions: Osteoarthritis of Knee
Interventions: DRUG: Clodronate|DRUG: Clodronate|DRUG: Clodronate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 68Ga-NODAGA-RGD PET in Patients With an Occluded Coronary Artery
Status: UNKNOWN
Conditions: Coronary Artery Disease
Interventions: DIAGNOSTIC_TEST: 68Ga-NODAGA-RGD PET-imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparative Study of EDP-420 Versus Another Antibiotic in the Treatment of Community Acquired Pneumonia
Status: UNKNOWN
Conditions: Community Acquired Pneumonia
Interventions: DRUG: EDP-420 / Duration of Treatment - 3 days|DRUG: Telithromycin / Duration of Treatment - 7 days
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Neuroprosthetic Device for Improving Issues Caused by Diabetic Neuropathy With Specifically Designed Neural Stimulation
Status: RECRUITING
Conditions: Neuropathy;Peripheral|Neuropathy, Diabetic|Neuropathy, Painful
Interventions: DEVICE: Somatosensory feedback
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Intrathecal Morphine on Urinary Bladder Function and Recovery in Patients Having a Cesarean Delivery
Status: COMPLETED
Conditions: Analgesia
Interventions: DRUG: 100 mcg morphine|DRUG: 0.9% NaCl|DRUG: 50 mg prilocaine + 2.5 mcg sufentanil|PROCEDURE: bilateral transverse abdominal plane block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study In Healthy People To Evaluate Safety, Toleration, Pharmacokinetics And Pharmacodynamics Of Multiple Oral Doses Of PF-06743649
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: PF-06743649|DRUG: Placebo|DRUG: PF-06743649|DRUG: Placebo|DRUG: PF-06743649|DRUG: Placebo|DRUG: PF-06743649|DRUG: Placebo|DRUG: PF-06743649|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Impact of Body Schema Distortion on Remission and Weight Regain in Anorexia Nervosa
Status: RECRUITING
Conditions: Anorexia Nervosa
Interventions: DEVICE: Body Map Assessment Tool: MOVE Tool|OTHER: PAQ questionnaire|OTHER: F-DFlex questionnaire|OTHER: BSQ questionnaire|OTHER: Silhouette testing|OTHER: Eating Disorder Inventory - 2|OTHER: EDEQ questionnaire|OTHER: STAI questionnaire|OTHER: BECK questionnaire
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: CKD-828 Drug Interaction Study (Telmisartan)
Status: COMPLETED
Conditions: Healthy Male Volunteers
Interventions: DRUG: Telmisartan 80mg, S-amlodipine 5mg|DRUG: Telmisartan 80mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Functional Lung Avoidance Radiation Therapy Using Hyperpolarized Xenon-129 MRI
Status: RECRUITING
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: COMBINATION_PRODUCT: Hyperpolarized xenon MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Systemic Absorption of Lidocaine After Hematoma Block
Status: WITHDRAWN
Conditions: Radius Fracture Distal|Hematoma|Lidocaine|Pediatrics
Interventions: DRUG: Lidocaine 1% Injectable Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vaccine Therapy, Paclitaxel, and Carboplatin in Treating Patients Who Are Undergoing Surgery for Stage III or Stage IV Ovarian Cancer, Primary Peritoneal Cancer, or Fallopian Tube Cancer
Status: TERMINATED
Conditions: Fallopian Tube Cancer|Ovarian Cancer|Primary Peritoneal Cavity Cancer
Interventions: BIOLOGICAL: MAGE-A1, Her-2/neu, FBP peptides ovarian cancer vaccine|BIOLOGICAL: tetanus toxoid helper peptide|DRUG: carboplatin|DRUG: paclitaxel|PROCEDURE: conventional surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antenatal Chlamydia Trachomatis and Neisseria Gonorrhoeae Testing to Prevent Adverse Neonatal Consequences
Status: COMPLETED
Conditions: Chlamydia Trachomatis Infection|Neonatal Infection|Preterm Birth|Gonorrhea
Interventions: OTHER: Chlamydia trachomatis and Neisseria gonorrhoeae screening using the GeneXpert
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: A Relative Bioavailability Study of 60 mg Nifedipine ER Tablets Under Non-fasting Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Nifedipine Extended Release tablets 60 mg, single dose|DRUG: ADALAT® CC Extended Release Tablets 60 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Effect of Neuronavigated Theta-Burst Transcranial Magnetic Stimulation (TBS) for Early Alzheimer's Disease
Status: RECRUITING
Conditions: Alzheimer Disease|Transcranial Magnetic Stimulation|Neuronavigation
Interventions: OTHER: transcranial magnetic stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Different Doses of Intravenous Administered Dexamethasone Effecting Brachial Plexus Supraclavicular Block
Status: NOT_YET_RECRUITING
Conditions: End Stage Renal Failure
Interventions: DRUG: supraclavicular block with 20mls of Ropivacaine 0.5% and Intravenous administered dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phenobarbital for Acute Alcohol Withdrawal
Status: COMPLETED
Conditions: Alcohol Withdrawal
Interventions: DRUG: 10 mg/kg IV phenobarbital in 100 ml saline|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Synergistic Effects of Anxiety and Alcohol Use Among Latinos and Its Sociocultural Mechanisms
Status: COMPLETED
Conditions: Alcohol Drinking|Racism
Interventions: OTHER: Alcohol administration|OTHER: Placebo|OTHER: No Alcohol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Nivolumab and Brentuximab Vedotin in Treating Older Patients With Untreated Hodgkin Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Ann Arbor Stage IB Hodgkin Lymphoma|Ann Arbor Stage II Hodgkin Lymphoma|Ann Arbor Stage IIA Hodgkin Lymphoma|Ann Arbor Stage IIB Hodgkin Lymphoma|Ann Arbor Stage III Hodgkin Lymphoma|Ann Arbor Stage IIIA Hodgkin Lymphoma|Ann Arbor Stage IIIB Hodgkin Lymphoma|Ann Arbor Stage IV Hodgkin Lymphoma|Ann Arbor Stage IVA Hodgkin Lymphoma|Ann Arbor Stage IVB Hodgkin Lymphoma|Classic Hodgkin Lymphoma
Interventions: DRUG: Brentuximab Vedotin|BIOLOGICAL: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Scientific Validation of the "Active Perineal Rehabilitation" Protocol to Urinary Incontinence Treatment
Status: UNKNOWN
Conditions: Urinary Incontinence
Interventions: BEHAVIORAL: Active Perineal Rehabilitation protocol|BEHAVIORAL: Kari Bo protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Dexamethasone and Bupivacaine Pain Control in Reduction Mammaplasty
Status: COMPLETED
Conditions: Pain, Postoperative|Mammaplasty
Interventions: DRUG: Dexamethasone 4mg|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Hypertonic Solution in Off Pump Coronary Artery Bypass Graft Surgery
Status: UNKNOWN
Conditions: Coronary Artery Disease
Interventions: DRUG: Hypertonic solution|DRUG: Isotonic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: LIVEBETTER: A Trial Comparing Medications in Older Adults With Stable Angina and Multiple Chronic Conditions
Status: RECRUITING
Conditions: Angina|Stable Ischemic Heart Disease
Interventions: OTHER: Clinician Discretion|DRUG: Beta blocker|DRUG: Calcium channel blocker
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Telerehabilitation Based Pain Neuroscience Education on Patients With Non-specific Chronic Neck Pain
Status: COMPLETED
Conditions: Neck Pain
Interventions: OTHER: Pain Neuroscience Education|OTHER: Progressive submaximal exercise program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Compare Peritoneal Ablation by Excision Only and Excision With the Use of an Adhesion Barrier
Status: UNKNOWN
Conditions: Endometriosis
Interventions: PROCEDURE: Excision plus hyaluronic acid gel|PROCEDURE: Excision only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Trial Evaluating multimOdal toPical Cream In CompArison to pLacebo (TOPICAL)
Status: TERMINATED
Conditions: Knee Osteoarthritis
Interventions: DRUG: Multiprofen|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dose-Optimization, Adjunctive Treatment Study of Ezogabine/Retigabine Immediate Release in Partial-onset Seizures
Status: TERMINATED
Conditions: Seizures
Interventions: DRUG: Ezogabine/Retigabine IR|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Early Phase II Trials for Cocaine Medication Development - 1
Status: COMPLETED
Conditions: Cocaine-Related Disorders|Substance-Related Disorders
Interventions: DRUG: Risperidone|DRUG: Placebo|BEHAVIORAL: Relapse prevention counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Probiotics and the Neurodevelopment in the Premature Infant <32 Weeks Gestational Age and <1500g
Status: ACTIVE_NOT_RECRUITING
Conditions: Infant, Newborn, Diseases|Infant Development
Interventions: DIETARY_SUPPLEMENT: Infloran® -Berne, Switzerland- (Bifidobacterium bifidum NCDO 2203 and Lactobacillus acidophilus NCDO 1748
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bauhinia Forficata in Diabetic Patients
Status: COMPLETED
Conditions: Diabetes
Interventions: DRUG: B. forficata|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Ketamine+Propofol vs Remifentanyl+Propofol on Laryngeal Mask Insertion Conditions
Status: COMPLETED
Conditions: Surgery
Interventions: DRUG: Ketamine|DRUG: remifentanyl|DRUG: propofol|DEVICE: laryngeal mask
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p