pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Multicenter Study Evaluating the Safety and Tolerability of Intravenous rhMBL in Liver Transplant Recipients.
Status: TERMINATED
Conditions: Liver Transplantation
Interventions: DRUG: Intravenous Recombinant Human Mannose-Binding Lectin (rhMBL)|DRUG: Intravenous Recombinant Human Mannose-Binding Lectin (rhMBL)|DRUG: Intravenous Recombinant Human Mannose-Binding Lectin (rhMBL)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intracoronary Infusion of BM-Derived Mononuclear Cells in Patients With Large Acute Myocardial Infarction
Status: UNKNOWN
Conditions: Myocardial Infarction
Interventions: PROCEDURE: Intracoronary mononuclear cell infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BCMA and CD19 Targeted Fast Dual CAR-T for BCMA+ Refractory/Relapsed Multiple Myeloma
Status: UNKNOWN
Conditions: Multiple Myeloma
Interventions: BIOLOGICAL: GC012F injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pain Relieving Potentials of Combination of Oral Duloxetine and Intravenous Magnesium Sulphate in Post Mastectomy Pain
Status: RECRUITING
Conditions: Post-mastectomy Pain Syndrome
Interventions: DRUG: Duloxetine and magnesium sulphate|DRUG: Duloxetine|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Aromatherapy for Integrated Cancer Care
Status: COMPLETED
Conditions: Cancer
Interventions: OTHER: Ginger aromatherapy|OTHER: Orange aromatherapy|OTHER: Lavender aromatherapy|OTHER: Jojoba aromatherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: PDR001 Combination Therapy for Radioiodine-Refractory Thyroid Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Thyroid Cancer|Thyroid Cancer, Follicular|Papillary Thyroid Cancer|Follicular Thyroid Cancer|Hurthle Cell Tumor|Poorly Differentiated Thyroid Gland Carcinoma|Hurthle Cell Thyroid Neoplasia
Interventions: DRUG: Trametinib|DRUG: Dabrafenib|DRUG: PDR001
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Continence, Sexual Function, Fitness and the Health of Men After Surgery for Prostate Cancer
Status: RECRUITING
Conditions: Prostate Cancer|Incontinence|Metabolic Disease
Interventions: BEHAVIORAL: Pelvic floor exercise program|BEHAVIORAL: General exercise|BEHAVIORAL: Physical Activity Counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Virtual Reality on Pain and Range of Motion on Burn
Status: COMPLETED
Conditions: Burns
Interventions: DEVICE: active assisted exercise and with fully immersive Head-Mounted Display virtual reality ( Oculus Quest virtual reality (VR) headset with hand con|OTHER: active assisted range of motion exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cognitive Frailty and Oxygen-ozone Therapy
Status: COMPLETED
Conditions: Cognitive Frailty
Interventions: OTHER: Experimental: Oxygen-Ozone (O2-O3)|OTHER: Active Comparator: Oxygen (O2)|OTHER: Placebo Comparator: Placebo (Air)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Diagnosing Corneal Infection
Status: NOT_YET_RECRUITING
Conditions: Corneal Ulcer (Diagnosis)
Interventions: DIAGNOSTIC_TEST: Corneal impression membrane (Millicell Cell Culture Insert, 12mm, hydrophilic PTFE 0.4µm (PICM01250))
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison Between Two Types of Sedation for Elective Upper Endoscopy Procedures
Status: COMPLETED
Conditions: Gastro Esophageal Reflux|Gastric Ulcer|Sedation Complication
Interventions: DRUG: Sevoflurane|DRUG: Midazolam injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Addition of Enoxaparin to Neoadjuvant Chemoradiation of Esophageal Cancer
Status: UNKNOWN
Conditions: Esophageal Neoplasms
Interventions: DRUG: Enoxaparin Sodium 40 MG/0.2 ML Subcutaneous Injectable|RADIATION: Radiotherapy|DRUG: Chemotherapeutic Combinations
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Thyme Honey in Management of Xerostomia in Post Radiation Cancer Patients
Status: COMPLETED
Conditions: Head and Neck Cancer Patients
Interventions: DRUG: thyme honey mouth rinse|DRUG: saline mouth rinse
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Morphological, Structural and Functional Neural Substrates of Quality of Life in Schizophrenia
Status: UNKNOWN
Conditions: Schizophrenia
Interventions: DEVICE: Magnetic Resonance Imaging|OTHER: EVALUATION NEUROPSYCHOLOGICAL
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Evaluating the Clinical Utility of the T-SPOT.CMV Assay for the Prediction of CMV Reactivation Among Pediatric Patients Undergoing Hematopoietic Cell Transplant
Status: TERMINATED
Conditions: CMV
Interventions: DIAGNOSTIC_TEST: T-SPOT®.CMV Test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of the SGLT2 Inhibitor Empagliflozin in Patients With Euvolemic and Hypervolemic Hyponatremia
Status: RECRUITING
Conditions: Hyponatremia|SIADH|Liver Failure|Kidney Failure
Interventions: DRUG: Empagliflozin 25 MG|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Selinexor in Combination With R-CHOP as the First-line Therapy for TP53-mutated DLBCL Patients (Smart Trial)
Status: RECRUITING
Conditions: Diffuse Large B Cell Lymphoma
Interventions: DRUG: Selinexor Oral Tablet [Xpovio]|DRUG: R-CHOP Protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study For Hypothermia Treatment In Hyperammonemic Encephalopathy In Neonates And Very Young Infants
Status: COMPLETED
Conditions: Urea Cycle Disorders|Organic Acidemias
Interventions: OTHER: Therapeutic Hypothermia|OTHER: Standard of Care Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Butyrate/Hexanoate in Metabolic Health
Status: COMPLETED
Conditions: Metabolic Disease
Interventions: DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: butyrate and hexanoate amount 1|DIETARY_SUPPLEMENT: butyrate and hexanoate amount 2|DIETARY_SUPPLEMENT: butyrate and hexanoate amount 3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Use of a Monitoring Device by General Practitioners During Out-of-hours Care
Status: UNKNOWN
Conditions: Emergencies|Heart Failure|Pulmonary Embolism|Acute Exacerbation of Chronic Obstructive Pulmonary Disease|Asthma|Acute Coronary Syndrome|Acute Myocardial Infarction|Atrial Fibrillation|Atrial Flutter|Hyperventilation|Pneumonia|Pneumothorax|Cardiac Arrest|Pulmonary Edema|Rhythm; Abnormal
Interventions: DEVICE: Use of the PICO(TM) monitoring device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Three Arm Rand Trial of HD Light vs Reveal® Cap vs Endocuff Cap for Detection of Colorectal Adenomas (TRACE)
Status: COMPLETED
Conditions: Colorectal Adenoma
Interventions: PROCEDURE: Colonoscopy|DEVICE: distal Cap|DEVICE: Endocuff
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Alemtuzumab-Ofatumumab in Previously Untreated Symptomatic Chronic Lymphocytic Leukemia
Status: ACTIVE_NOT_RECRUITING
Conditions: Stage I Chronic Lymphocytic Leukemia|Stage II Chronic Lymphocytic Leukemia|Stage III Chronic Lymphocytic Leukemia|Stage IV Chronic Lymphocytic Leukemia
Interventions: BIOLOGICAL: alemtuzumab|BIOLOGICAL: ofatumumab|PROCEDURE: biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Pharmacokinetics and Safety of TPN171H Tablets in Subjects With Mild ,Moderate Hepatic Insufficiency and Normal Liver Function
Status: COMPLETED
Conditions: Erectile Dysfunction|Pulmonary Arterial Hypertension
Interventions: DRUG: TPN171H
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open Retropubic Versus Laparoscopic Colposuspension (Burch Operation) Techniques for Female Stress or Mixed Urinary Incontinence; A Ten-year Experience in a Tertiary Center
Status: COMPLETED
Conditions: Stress Urinary Incontinence
Interventions: PROCEDURE: Burch colposuspension
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: RCT Comparing ESPB Solutions in Breast Surgery
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Liposomal bupivacaine|DRUG: Bupivacaine, epinephrine, dexamethasone, and clonidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Train the Trainer Curriculum to Scale up AI Supported Echo for RHD Screening in a Public Health System
Status: COMPLETED
Conditions: Rheumatic Heart Disease
Interventions: OTHER: Primary Training Phase|OTHER: Primary Assessment Phase|OTHER: Primary Screening Phase|OTHER: Secondary Training Phase|OTHER: Secondary Assessment Phase|OTHER: Secondary Screening Phase
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Evaluation of the Safety and Efficacy of the Multilayer Stent
Status: COMPLETED
Conditions: Aortic Aneurysm, Thoracoabdominal|Thoracoabdominal Aortic Aneurysm|Aortic Aneurysm, Thoracic
Interventions: DEVICE: MFM
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Study of Wound Closure at Time of Cesarean Delivery: Dermabond Glue Versus Surgical Staples
Status: TERMINATED
Conditions: Cesarean Section
Interventions: DEVICE: Surgical skin staples|DEVICE: Dermabond
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Yttrium-90-labeled Daclizumab With Chemotherapy and Stem Cell Transplant for Hodgkin's Lymphoma
Status: TERMINATED
Conditions: Hodgkin Disease|Hodgkin Lymphoma
Interventions: PROCEDURE: Auto stem cell transplant|DRUG: BEAM|RADIATION: 111In-daclizumab|RADIATION: 90Y-daclizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TEZSPIRE (Tezepelumab) Asthma Japan Post-Marketing Study (PMS)
Status: RECRUITING
Conditions: Bronchial Asthma (Only the Patients With Severe or Intractable Bronchial Asthma Which Could Not be Controlled With the Existing Therapy)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Gait Training With a Walking Assist Robot on Gait Function and Balance in Patients With Chronic Stroke
Status: COMPLETED
Conditions: Gait Disorders, Neurologic|Stroke
Interventions: DEVICE: Samsung Hip Assist v1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Human Autologous MSCs for the Treatment of Mid to Late Stage Knee OA
Status: COMPLETED
Conditions: Osteoarthritis of Knee
Interventions: BIOLOGICAL: 1 x 10^6 MSCs|BIOLOGICAL: 10 x 10^6 MSCs|BIOLOGICAL: 50 x 10^6 MSCs
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Clinical Study of Umbilical Cord Mesenchymal Stem Cells Infusion for Aging Frailty
Status: COMPLETED
Conditions: Aging Frailty
Interventions: BIOLOGICAL: Human umbilical cord mesenchymal stem cells（HUC-MSCs）|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Celiprolol in Patients With Ehlers-Danlos Syndrome, Vascular Type
Status: COMPLETED
Conditions: EHLERS-DANLOS SYNDROME, TYPE IV, AUTOSOMAL DOMINANT|CHROMOSOME 2q31.2 DELETION SYNDROME
Interventions: DRUG: celiprolol|DRUG: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Repetitive Transcranial Magnetic Stimulation (rTMS) to Promote Hand Recovery in Stroke
Status: COMPLETED
Conditions: Stroke
Interventions: DEVICE: rTMS|PROCEDURE: Motor learning training|PROCEDURE: rTMS and Tracking|DEVICE: Sham rTMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of CB-183,315 in Participants With Clostridium Difficile Associated Diarrhea (MK-4261-006)
Status: COMPLETED
Conditions: Clostridium Difficile Infection
Interventions: DRUG: CB-183,315|DRUG: Vancomycin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Continuous Versus Discontinuous Suture in the Perineals Lesions
Status: COMPLETED
Conditions: Perineal Tear|Episiotomy Wound
Interventions: PROCEDURE: Continuous suture in the perineals lesions|PROCEDURE: Discontinuous suture in the perineals lesions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Study to Evaluate Pharmacokinetics, Food Effect, Safety and Efficacy of Oral Azacitidine
Status: COMPLETED
Conditions: Myelodysplastic Syndromes|Leukemia, Myelomonocytic, Chronic|Leukemia, Myeloid, Acute
Interventions: DRUG: oral azacitidine|DRUG: oral azacitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An IT Approach to Implementing Depression Treatment in Cardiac Patients (iHeart DepCare)
Status: RECRUITING
Conditions: Depressive Symptoms|Coronary Heart Disease
Interventions: BEHAVIORAL: Electronic shared decision making (eSDM) tool
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Open-Label Study of Efficacy and Safety of Recombinant Human N-acetylgalactosamine 4-sulfatase in Patients With MPS VI
Status: COMPLETED
Conditions: Mucopolysaccharidosis VI
Interventions: DRUG: N-acetylgalactosamine 4-sulfatase
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Mitochondrial Function in Myofascial Trigger Points Cohort Pilot Study Using High-resolution Respirometry
Status: COMPLETED
Conditions: Pain, Neck|Pain, Back|Myofascial Trigger Point Pain|Myofascial Pain|Mitochondrial Pathology
Interventions: PROCEDURE: Muscle biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Three Combinations Of Docetaxel And Irinotecan For Recurrent Or Metastatic Non Small Cell Lung Cancer
Status: COMPLETED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: Irinotecan|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Two-Weekly Intravenous Mircera for the Treatment of Dialysis Patients With Chronic Renal Anemia Not Receiving ESA Therapy.
Status: COMPLETED
Conditions: Anemia
Interventions: DRUG: methoxy polyethylene glycol-epoetin beta [Mircera]
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Research Study to Investigate How Well Semaglutide Works in People Living With Heart Failure and Obesity
Status: COMPLETED
Conditions: Obesity
Interventions: DRUG: Semaglutide|DRUG: Placebo (semaglutide)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare the Safety and Efficacy of an Aromatase Inhibitor in Combination With Lapatinib, Trastuzumab or Both for the Treatment of Hormone Receptor Positive, HER2+ Metastatic Breast Cancer
Status: COMPLETED
Conditions: Neoplasms, Breast
Interventions: DRUG: lapatinib|DRUG: trastuzumab|DRUG: Aromatase inhibitor|DRUG: lapatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vitamin D as a Therapeutic Adjunct in the Stimulant Treatment of ADHD: a Proof-of-concept Tele-health Study of Stimulant-induced Improvement in Neurocognitive Functioning.
Status: TERMINATED
Conditions: ADHD
Interventions: DRUG: Calcitriol|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Comparison of a Non Contact Vital Signs Application With Traditional Pulse Oximetry for Heart Rate Measurement
Status: NOT_YET_RECRUITING
Conditions: Heart
Interventions: DEVICE: Darwin smartphone app|DEVICE: Pulse oxymetry
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effects of Tai Chi on Postural Balance and Quality of Life in the Elderly With Gait Disorder
Status: RECRUITING
Conditions: Gait Disorder|Postural Balance
Interventions: OTHER: Tai Chi|OTHER: Daily activity group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pharmacokinetics of Bisacodyl or Sodium Picosulfate Administered Orally in Healthy Lactating Females
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Bisacodyl|DRUG: Sodium picosulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: AYAHIV Role-based Responsibilities for Oncology-focused Workforce (ARROW)
Status: RECRUITING
Conditions: Cervical Cancer|Kaposi Sarcoma|Non Hodgkin Lymphoma
Interventions: OTHER: ARROW strategies|OTHER: One-time education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Efficacy of Allogeneic UCMSCs for Treating Large Defects Knee Injury
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: BIOLOGICAL: Human umbilical cord-derived mesenchymal stem cells (hUC-MSCs)|PROCEDURE: Marrow cellution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Primary Glaucoma Treatment Trial in Kenya and South Africa - SLT vs. Medication
Status: TERMINATED
Conditions: Glaucoma
Interventions: DRUG: Prostaglandin analogue|PROCEDURE: Selective laser trabeculoplasy|DEVICE: laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aggressive Medical Treatment Evaluation for Asymptomatic Carotid Artery Stenosis
Status: TERMINATED
Conditions: Carotid Artery Stenosis|Atherosclerosis|Stroke
Interventions: PROCEDURE: Carotid Endarterectomy|DRUG: atorvastatin, aspirin, losartan, amlodipine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy of a New Therapy as Adjunctive Therapy to Anti-vascular Endothelial Growth Factor (Anti-VEGF) in Subjects With Wet Age-Related Macular Degeneration (AMD)
Status: COMPLETED
Conditions: Choroidal Neovascularization|Age-Related Maculopathy
Interventions: DRUG: dexamethasone|BIOLOGICAL: ranibizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Assess Analgesia Provided by Continuous Sciatic Nerve Block in Patients With Hypertensive Leg Ulcer
Status: COMPLETED
Conditions: Hypertensive Leg Ulcer
Interventions: DRUG: Ropivacaïne
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Efficacy and Safety of E004 in Children With Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: E004 (Epinephrine Inhalation Aerosol) HFA-MDI|DRUG: Placebo-HFA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Exercises on Hamstring Muscle Function, Injury Risk, Agility and Cognitive Function
Status: COMPLETED
Conditions: Hamstring Muscles|Muscle Function|Cognitive Function|Turkish Get Up
Interventions: OTHER: Turkish Get-up exercise|OTHER: Askling L-Protocol|OTHER: Nordic hamstring exercise|OTHER: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HoLEP in Management of BPH Patients With Predominant Voiding vs Storage LUTS: A Comparative Retrospective Study
Status: COMPLETED
Conditions: Benign Prostatic Hyperplasia (BPH)
Interventions: DEVICE: Holmium Laser Enucleation of Prostate
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Potassium Chloride in Out-of-hospital Cardiac Arrest Due to Refractory Ventricular Fibrillation
Status: WITHDRAWN
Conditions: Out-of-hospital Cardiac Arrest (OHCA)
Interventions: DRUG: Potassium chloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sufentanil as Adjuvant of Balanced Anesthesia
Status: COMPLETED
Conditions: Anesthesia
Interventions: DRUG: Sufentanil|DRUG: Remifentanil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study to Evaluate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Alobresib (Formerly GS-5829) in Adults With Advanced Solid Tumors and Lymphomas and in Combination With Exemestane or Fulvestrant in Adults With Estrogen Receptor Positive Breast Cancer
Status: COMPLETED
Conditions: Solid Tumors and Lymphomas
Interventions: DRUG: Alobresib|DRUG: Exemestane|DRUG: Fulvestrant
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Implementing Tobacco Use Treatment in HIV Clinics Vietnam
Status: RECRUITING
Conditions: Tobacco Use
Interventions: BEHAVIORAL: Ask, advise, Assist and refer to the Quitline|BEHAVIORAL: Ask, advise, Assist and referral to onsite counselor|BEHAVIORAL: Ask, advise, Assist and referral to onsite counselor and NRT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevention of Venous Obstruction After Implantation of Cardiac Pacemaker and Defibrillator
Status: UNKNOWN
Conditions: Complication of Cardiac Defibrillator|Disorder of Cardiac Pacemaker System|Venous Occlusion
Interventions: DRUG: placebo|DRUG: Aspirin 80 mg daily|DRUG: Clopidogrel 75 mg daily
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: AMIloride for the Treatment of Nephrogenic Diabetes Insipidus for Patients With Bipolar Disorder Treated With Lithium
Status: RECRUITING
Conditions: Bipolar Disorder
Interventions: DRUG: Anhydrous Amiloride Hydrochloride|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intravesical Gemcitabine Instillation Followed by Transurethral Resection for the Treatment of Patients With Superficial Bladder Cancer at Low Risk.
Status: COMPLETED
Conditions: Superficial Bladder Cancer
Interventions: DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Postoperative Pain Application of Alfentanil or Remifentanil in TIVA
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: Propofol combined with alfentanil|DRUG: Propofol combined with remifentanil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective Validation of Adaptive Radiotherapy (ART) in Patients With Head and Neck Tumors
Status: RECRUITING
Conditions: Head and Neck Cancer|Adaptive Radiotherapy|Radiation|Optimized Treatment|Protection of Organs at Risk|Dysphagia Reduction
Interventions: RADIATION: Adaptive Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Standard Maintenance POMP/D Plus Ixazomib Maintenance Therapy in Adult Patients With Acute Lymphoblastic Leukemia, Lymphoblastic Lymphoma or Mixed Phenotype Acute Leukemia in Complete Remission (CR)
Status: WITHDRAWN
Conditions: Acute Lymphoblastic Leukemia in Complete Remission|Lymphoblastic Lymphoma in Complete Remission|Mixed Phenotype Acute Leukemia in Complete Remission
Interventions: DRUG: Ixazomib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High Low Biphasic Energy Defibrillation (HiLoBED)
Status: UNKNOWN
Conditions: Ventricular Fibrillation
Interventions: PROCEDURE: Cardiac defibrillation at high energy vs low energy levels
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Meridian Yoga on Chemotherapy-induced Peripheral Neuropathy in Breast Cancer Patients
Status: NOT_YET_RECRUITING
Conditions: CIPN - Chemotherapy-Induced Peripheral Neuropathy|Breast Cancer
Interventions: OTHER: yoga
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Sacituzumab Tirumotecan (MK-2870) in Advanced/Metastatic Gastroesophageal Adenocarcinoma (MK-2870-015)
Status: RECRUITING
Conditions: Gastroesophageal Cancer
Interventions: BIOLOGICAL: Sacituzumab tirumotecan|DRUG: Trifluridine-Tipiracil|DRUG: Irinotecan|DRUG: Paclitaxel|DRUG: Docetaxel|DRUG: Rescue medication|DRUG: Supportive care measures
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Open Label Study to Assess the Efficacy, Safety and Tolerability of COZAAR Plus (Losartan Potassium 50mg/Hydrochlorothiazide 12.5mg) Possibly Titrated up to COZAAR Plus-F (Losartan Potassium 100mg/Hydrochlorothiazide 25mg) in Patients With Essential Hypertension (0954A-325)
Status: TERMINATED
Conditions: Hypertension
Interventions: DRUG: MK0954, losartan potassium / Duration of Treatment - 12 weeks
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dexmedetomidine vs Fentanyl on Time to Extubation in Patients Undergoing Laparoscopic Sleeve Gastrectomy
Status: COMPLETED
Conditions: Dexmedetomidine|Fentanyl|Time to Extubation|Morbid Obesity|Laparoscopic Sleeve Gastrectomy
Interventions: DRUG: Group F (fentanyl group)|DRUG: Group D (dexmedetomidine group)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Discontinuing Disease-modifying Therapies in Stable Relapsing - Onset Multiple Sclerosis (DOT-MS).
Status: UNKNOWN
Conditions: Multiple Sclerosis|Multiple Sclerosis, Relapsing-Remitting|Multiple Sclerosis, Secondary Progressive
Interventions: DRUG: DMT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Does a ThoracoLumbar Interfacial Plane (TLIP) Block With Liposomal Bupivacaine Provide TLIP Block in Spinal Surgery
Status: UNKNOWN
Conditions: Pain, Postoperative
Interventions: DRUG: Liposomal bupivacaine|DRUG: Bupivacaine Injection|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Furosemide Inhalation in Dyspnea of Mustard Gas Exposed Patients
Status: COMPLETED
Conditions: Bronchiolitis
Interventions: DRUG: furosemide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy of Ramelteon on Insomnia Symptoms Associated With Jet Lag in Healthy Adult Volunteers
Status: COMPLETED
Conditions: Circadian Dysregulation
Interventions: DRUG: Ramelteon|DRUG: Ramelteon|DRUG: Ramelteon|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Rosiglitazone on Plasma BNP Levels and Left Ventricular Dysfunction
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Rosiglitazone(drug), cardiac adverse effects
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Most Effective Intervention for Reducing Posterior Shoulder Tightness Acutely in the Post-operative Population
Status: COMPLETED
Conditions: Postoperative Posterior Shoulder Tightness
Interventions: OTHER: Horizontal Adduction Stretch and Pendulums|OTHER: Modified Sleeper Stretch and Pendulum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Influence of Bilateral Arm Ischemic Postconditioning on Clinical Prognosis and Outcome in Acute Ischemic Stroke Patients
Status: UNKNOWN
Conditions: Remote Ischemic Postconditioning
Interventions: OTHER: Remote Ischemic Conditioning Equipment|PROCEDURE: Intravenous blood collection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Polyunsaturates and KCL to Control Mild Hypertension
Status: COMPLETED
Conditions: Cardiovascular Diseases|Heart Diseases|Hypertension|Vascular Diseases
Interventions: DIETARY_SUPPLEMENT: mineral supplements|DIETARY_SUPPLEMENT: Trial 1: fatty acids, omega-3; Trial 2: Mineral supplements|BEHAVIORAL: dietary supplements
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: |Primary Purpose: TREATMENT
Clinical trial: Reduced Total Blood Loss and Blood Transfusion in Non-Septic Revision Knee Arthroplasty Using a Bipolar Sealer
Status: COMPLETED
Conditions: Total Blood Loss
Interventions: DEVICE: Bipolar sealer
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Post Thyroidectomy Echographic Method for Study of Vocal Fold Motion
Status: RECRUITING
Conditions: Recurrent Laryngeal Nerve Palsy|Postoperative Dysphonia
Interventions: DEVICE: Transcutaneous Laryngeal Ultrasonography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Use of Serious Game Simulation on Newborn Resuscitation Education
Status: COMPLETED
Conditions: Newborn; Vitality
Interventions: BEHAVIORAL: Neonatal resuscitation training with classical method and serious game simulation method|BEHAVIORAL: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Safety and Immunogenicity Study of Live Attenuated Indian Rotavirus Vaccine Candidate Strains 116E and I321 in Infants
Status: COMPLETED
Conditions: Rotavirus Infections
Interventions: BIOLOGICAL: 116E AGMK|DRUG: I321|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Opioid Titration Order Sheet or Standard Care in Treating Patients With Cancer Pain
Status: COMPLETED
Conditions: Brain and Central Nervous System Tumors|Chronic Myeloproliferative Disorders|Leukemia|Lymphoma|Lymphoproliferative Disorder|Multiple Myeloma and Plasma Cell Neoplasm|Myelodysplastic Syndromes|Myelodysplastic/Myeloproliferative Neoplasms|Pain|Precancerous Condition|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: OTHER: educational intervention|OTHER: Titrated pain management|OTHER: questionnaire administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Docetaxel and Cisplatin With or Without Dimesna in Treating Patients With Stage IIIB or Stage IV Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Anemia|Drug/Agent Toxicity by Tissue/Organ|Lung Cancer|Neutropenia
Interventions: BIOLOGICAL: darbepoetin alfa|BIOLOGICAL: pegfilgrastim|DRUG: cisplatin|DRUG: docetaxel|DRUG: BNP7787
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mineralocorticoid Receptor Antagonist and Pulmonary Fibrosis in COVID-19.
Status: UNKNOWN
Conditions: COVID-19 Pneumonia
Interventions: DRUG: Canrenoate Potassium|DRUG: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Incidence of Hypophosphatemia After Treatment With Iron Isomaltoside/Ferric Derisomaltose vs Ferric Carboxymaltose in Subjects With Iron Deficiency Anaemia
Status: COMPLETED
Conditions: Iron Deficiency Anaemia|Iron Deficiency Anemia
Interventions: DRUG: Iron isomaltoside/ferric derisomaltose|DRUG: Ferric carboxymaltose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Communication and Coping for Mothers of Adolescents With Type 1 Diabetes
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus
Interventions: BEHAVIORAL: Communication & Coping Intervention|BEHAVIORAL: Education & Check Ins
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Benefit of Carbohydrate Deficient Transferrin to Detect Chronic Alcohol Abuse in the Elderly
Status: COMPLETED
Conditions: Alcohol Abuse
Interventions: BEHAVIORAL: Alcohol Used Disorders Identification Test (AUDIT C)|PROCEDURE: Carbohydrate deficient transferrin|PROCEDURE: Gamma glutamyl transpeptidase|PROCEDURE: Mean Corpuscular Volume
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparative Evaluation of Post Endodontic Pain Following Root Canal Treatment With Two Rotary System: Neolix & Waveone
Status: UNKNOWN
Conditions: Pain, Postoperative Pain Pathologic Processes Postoperative Complications Signs and Symptoms
Interventions: PROCEDURE: neolix rotary system (continuous rotation system)|PROCEDURE: waveone rotary system (reciprocating system)|PROCEDURE: hand files k-files
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Baricitinib and Rifampicin in Healthy Participants
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Baricitinib|DRUG: Rifampicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of Cyclophosphamide/Methotrexate/5-Fluorouracil (CMF) With Pegfilgrastim in Subjects With Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: pegfilgrastim|DRUG: cyclophosphamide|DRUG: methotrexate|DRUG: 5-fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Effect of Repaglinide and Metformin Combination Tablet or Rosiglitazone and Metformin in Fixed Dose Combination on Blood Glucose Control in Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: repaglinide and metformin combination tablet|DRUG: rosiglitazone and metformin combination tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Parental Attitudes and Beliefs Regarding Risks Associated With Opioid Use in Children With Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Hematopoietic and Lymphoid Cell Neoplasm|Malignant Solid Neoplasm
Interventions: OTHER: Electronic Health Record Review|OTHER: Survey Administration
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase II Study of IGEV +/- Bortezomib Before Hign Dose Consolidation in Relapsed/Refractory Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Hodgkin Disease
Interventions: DRUG: Ifosfamide, Gemcitabine, Vinorelbine|DRUG: Bortezomib + IGEV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Two Years Survival Rate of Class II ART Restorations in Primary Molars Using Two Ways to Avoid Saliva Contamination
Status: COMPLETED
Conditions: Dental Caries
Interventions: PROCEDURE: Atraumatic Restorative Technique using cotton rolls|PROCEDURE: Atraumatic Restorative Technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Quality of Life and Cosmetic Outcomes of Breast-Conserving Surgery According to Localization Method
Status: RECRUITING
Conditions: Breast Cancer
Interventions: PROCEDURE: Wire-guided surgery|PROCEDURE: Radioactive seed localization|PROCEDURE: Intraoperative ultrasound localization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reducing Skin Cancer Risk in Childhood Cancer Survivors
Status: COMPLETED
Conditions: Skin Neoplasms
Interventions: BEHAVIORAL: Patient activation and education (PAE)|BEHAVIORAL: PAE plus physician activation (PAE + MD)|BEHAVIORAL: PAE physician activation, plus teledermoscopy (PAE +MD +TD)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SCREENING
Clinical trial: Safety of Urate Elevation in Amyotrophic Lateral Sclerosis (ALS)
Status: COMPLETED
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DRUG: Inosine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: TACE Plus Atezolizumab/Bevacizumab and I-125 Seeds Brachytherapy for HCC With Branch PVTT
Status: NOT_YET_RECRUITING
Conditions: Hepatocellular Carcinoma|Hepatic Portal Vein Tumor Invasion|Tumor Thrombus
Interventions: PROCEDURE: I-125 Seeds Brachytherapy in PVTT|PROCEDURE: Transcatheter arterial chemoembolization|DRUG: Atezolizumab plus Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Omega-3 Supplementation and Resistance Training
Status: COMPLETED
Conditions: Sarcopenia|Dynapenia|Inflammation
Interventions: DIETARY_SUPPLEMENT: Omega-3 Supplementation|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Breast Cancer Study: Paclitaxel Versus Paclitaxel Plus Sorafenib in Second- or Third-line Treatment
Status: COMPLETED
Conditions: Metastatic Breast Cancer
Interventions: DRUG: Paclitaxel and Sorafenib|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Beta-Cell Function and Sitagliptin Trial (BEST)
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Sitagliptin|DRUG: Placebo|DRUG: metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess an Enteric Microgranule Formulation of Adrulipase in Patients With Cystic Fibrosis
Status: COMPLETED
Conditions: Exocrine Pancreatic Insufficiency|Cystic Fibrosis
Interventions: DRUG: adrulipase
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Virtual Therapy as a Method Supporting Treatment of Late-Life Depression
Status: COMPLETED
Conditions: Depressive Symptoms|Depression|Anxiety
Interventions: DEVICE: VRTierOne|BEHAVIORAL: Group general fitness training|BEHAVIORAL: Group Psychoeducation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of FluLaval™ TR and Fluarix® (Influenza Vaccines) in Young and Older Adults
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Influenza vaccine (A/H3N2, A/H1N1, and B strains)|BIOLOGICAL: Fluarix
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Clofarabine for Myelodysplastic Syndrome (MDS) Patients Who Failed Vidaza Treatment (tx)
Status: TERMINATED
Conditions: Myelodysplastic Syndromes
Interventions: DRUG: Clofarabine|DRUG: Clofarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Pulmonary Rehabilitation on Respiratory Sounds in Patients With COPD
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: BEHAVIORAL: Pulmonary rehabilitation|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Treatment of Neonatal Abstinence Syndrome With Clonidine Versus Morphine as Primary Therapy
Status: RECRUITING
Conditions: Neonatal Abstinence Syndrome
Interventions: DRUG: Clonidine|DRUG: Morphine Sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: NuVasive® ACP System Study
Status: ENROLLING_BY_INVITATION
Conditions: Cervical Spondylosis|Cervical Radiculopathy|Cervical Myelopathy|Cervical Disc Disease|Cervical Stenosis|Cervical Disc Herniation|Cervical Spine Disease
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: FMT Delivered by Capsule Versus Colonoscopy for Recurrent C. Diff
Status: COMPLETED
Conditions: Enterocolitis Clostridium Difficile Recurrent
Interventions: BIOLOGICAL: Fecal Microbiota Transplant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Dose Titration Study to Assess the Effects of SAR407899 in Patients With MVA and/or Persistent Stable Angina Despite Angiographically Successful PCI
Status: TERMINATED
Conditions: Microvascular Coronary Artery Disease
Interventions: DRUG: SAR407899|DRUG: Placebo|DRUG: Adenosine|DRUG: Regadenoson|DRUG: 13N-ammonia|DRUG: 82Rubidium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Electrical Epidural Stimulation Test for Detecting Epidural Catheter Reactivation in Obstetric Population
Status: NOT_YET_RECRUITING
Conditions: Obstetric Pain|Anesthesia, Local
Interventions: DIAGNOSTIC_TEST: Electrical Epidural Stimulation Test (EST)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluating PN 400 (VIMOVO) in Reducing Gastric Ulcers Compared to Non-steroidal Antiinflammatory Drug (NSAID) Naproxen
Status: COMPLETED
Conditions: Gastric Ulcer
Interventions: DRUG: PN400 (VIMOVO)|DRUG: Naproxen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT