pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Clinical Study to Assess Safety and Effectiveness of the Zenith® Dissection Endovascular System in Patients With Aortic Dissection
Status: COMPLETED
Conditions: Aortic Dissection Involving the Descending Thoracic Aorta
Interventions: DEVICE: Zenith® Dissection Endovascular System|DEVICE: Endovascular Repair
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Chewing Gum in Hemodialysis Patients
Status: COMPLETED
Conditions: Mouth Dryness|Nausea|Hemodialysis Complication|Nurse's Role|Thirst
Interventions: OTHER: Gum Group:|OTHER: Mouth Spray Group:
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Pilot Study of Ciprofloxacin Plus Gemcitabine and Nab-Paclitaxel Chemotherapy in Patients With Metastatic Pancreatic Ductal Adenocarcinoma.
Status: UNKNOWN
Conditions: Metastatic Pancreatic Ductal Adenocarcinoma
Interventions: DRUG: Ciprofloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rapid Dose Escalation of Quetiapine Versus Conventional Escalation in Acute Schizophrenic Patients
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: IR (Immediate-Release) quetiapine fumarate (drug)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: IPI-Biotherapy for Patients Previously Treated With Cytotoxic Drugs With Metastatic Melanoma
Status: WITHDRAWN
Conditions: Melanoma
Interventions: DRUG: Ipilimumab|DRUG: Interferon|DRUG: Interleukin-2 (Aldesleukin)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomised Controlled Trial of Electroconvulsive Therapy (ECT) in Relapse Prevention of Depression
Status: COMPLETED
Conditions: Depressive Disorder, Major
Interventions: PROCEDURE: Electroconvulsive therapy|DRUG: venlafaxine|DRUG: Lithium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: rTMS Efficacy Coupled With Mirror Therapy
Status: RECRUITING
Conditions: Neuropathic Pain
Interventions: OTHER: Repetitive transcranial magnetic stimulation (rTMS)|OTHER: Mirror therapy using virtual reality|OTHER: Mirror therapy using sham mirror
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: PhII ICb With/Without Erbitux in MBC Pts
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Breast Cancer
Interventions: DRUG: Irinotecan + Carboplatin|DRUG: irinotecan + Carboplatin + erbitux
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Evaluate the Efficacy and Safety of TQB2440 Injection/Perjeta® Combined With Trastuzumab and Docetaxel in the Treatment of Patients With Early or Locally Advanced Breast Cancer.
Status: ACTIVE_NOT_RECRUITING
Conditions: HER2-positive Breast Cancer
Interventions: DRUG: TQB2440 injection + Trastuzumab + Docetaxel|DRUG: Perjeta + Trastuzumab + Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Arousal-Biofeedback for the Treatment of Aggressive Behavior in Children and Adolescents
Status: COMPLETED
Conditions: Aggression|Conduct Disorder|Oppositional Defiant Disorder
Interventions: BEHAVIORAL: Individualized Arousal-Biofeedback|BEHAVIORAL: Treatment as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Addressing Barriers to Care for Substance Use Disorder Pilot Study
Status: RECRUITING
Conditions: Drug Use Disorders|Illicit Drug Use|Alcohol-Related Disorders
Interventions: BEHAVIORAL: Care Navigation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Analysis of the Correlation Between Ultrasound Imaging and Functional Parameters in the Medial Gastrocnemius Muscle in Post-stroke Patients With Spasticity in the Lower Limb
Status: ENROLLING_BY_INVITATION
Conditions: Stroke|Spasticity, Muscle
Interventions: DIAGNOSTIC_TEST: Ultrasound imaging and functional assessment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pericapsular Nerve Group Block Versus Lumber Erector Spinae Plane Block for Pain Management After Total Hip Arthroplasty
Status: UNKNOWN
Conditions: Post Operative Pain, Chronic
Interventions: PROCEDURE: PENG block|PROCEDURE: lumbar erector spinae plane block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effect of Cord Milking on Hemodynamic Status of Preterm Infants
Status: UNKNOWN
Conditions: Preterm Infants
Interventions: PROCEDURE: Milking the umbilical cord at birth|PROCEDURE: immediate umbilical cord clamping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Single Dose Pharmacology Study of DG3173 and Octreotide in Acromegalic Patients.
Status: COMPLETED
Conditions: Acromegaly
Interventions: DRUG: octreotide|DRUG: DG3173
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Cosmetic Performance of AIR OPTIX® COLORS
Status: COMPLETED
Conditions: Cosmetic Appearance
Interventions: DEVICE: Lotrafilcon B contact lens with color|DEVICE: Phemfilcon A contact lens with color
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: Irradiated Donor Lymphocyte Infusion in Treating Patients With Relapsed or Refractory Hematologic Cancer or Solid Tumor
Status: COMPLETED
Conditions: Cancer
Interventions: BIOLOGICAL: therapeutic allogeneic lymphocytes
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chest X-Ray or Chest CT Scan in Patients at High Risk of Developing Lung Cancer
Status: UNKNOWN
Conditions: Lung Cancer
Interventions: PROCEDURE: annual screening|PROCEDURE: bronchoscopic and lung imaging studies|PROCEDURE: comparison of screening methods|PROCEDURE: computed tomography|PROCEDURE: radiography|PROCEDURE: study of high risk factors
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: SCREENING
Clinical trial: Multiple N-of-1 Trials of (Intermittent) Hypoxia Therapy in Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson Disease|Effect of Drug
Interventions: DRUG: Hypoxic Gas Mixture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pain in Single Incision Laparoscopic Surgery Cholecystectomy
Status: COMPLETED
Conditions: Laparoscopic Cholecystectomy
Interventions: PROCEDURE: Laparoscopic Cholecystectomy|PROCEDURE: SILS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Innervation of Vascularized Iliac Transplant Avoids Resorption in Jaw Bone Reconstruction
Status: UNKNOWN
Conditions: Bone Resorption|Nerve
Interventions: PROCEDURE: Innervation|PROCEDURE: Non-innervation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Atorvastatin in Relapsing-Remitting Multiple Sclerosis
Status: COMPLETED
Conditions: Relapsing Remitting Multiple Sclerosis
Interventions: DRUG: interferon beta treatment to add-on atorvastatin treatment|DRUG: untreated to atorvastatin treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Methylphenidate, Rivastigmine or Haloperidol in Hypoactive Delirium in Intensive Care Patients
Status: TERMINATED
Conditions: Delirium
Interventions: DRUG: Haloperidol|DRUG: Methylphenidate|DRUG: Rivastigmine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Television Viewing (TVV) & Puberty on Lunchtime Food Intake
Status: COMPLETED
Conditions: Obesity Prevention
Interventions: DIETARY_SUPPLEMENT: water with noncalorie sweetener|DIETARY_SUPPLEMENT: water with glucose|BEHAVIORAL: TV program showed while feeding|BEHAVIORAL: TV program showed while feeding
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Hemodynamic Response to Angiotensin-II When Used as the Second Vasopressor Agent for Septic Shock
Status: RECRUITING
Conditions: Septic Shock|Shock|Sepsis|Systemic Inflammatory Response Syndrome
Interventions: DRUG: Angiotensin II and hydrocortisone sodium succinate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy and Radiation Therapy With or Without Efaproxiral in Treating Patients With Stage III Non-Small Cell Lung Cancer
Status: WITHDRAWN
Conditions: Lung Cancer
Interventions: DRUG: carboplatin|DRUG: cisplatin|DRUG: efaproxiral|DRUG: gemcitabine hydrochloride|DRUG: paclitaxel|DRUG: vinorelbine ditartrate|PROCEDURE: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Silver Diamine Fluoride on Local Anesthesia in Hypomineralized Molars
Status: RECRUITING
Conditions: Molar Incisor Hypomineralization|Anesthesia, Local
Interventions: DEVICE: SDF|DEVICE: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: AMG 479 in Advanced Carcinoid and Pancreatic Neuroendocrine Tumors
Status: COMPLETED
Conditions: Neuroendocrine Tumor|Carcinoid Tumor|Pancreatic Neuroendocrine Tumor
Interventions: DRUG: AMG 479
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Conventional Techniques & Piezosurgery in the Management of the Nasal Bony Pyramid
Status: COMPLETED
Conditions: Nasal Injury
Interventions: PROCEDURE: Conventional osteotomy|PROCEDURE: Piezosurgery osteotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: tDCS as Adjunctive Therapy to Cognitive Stimulation in Medical Students With Depression
Status: ACTIVE_NOT_RECRUITING
Conditions: Clinical Trial
Interventions: DEVICE: transcranial direct current stimulation|OTHER: cognitive stimulation|DEVICE: sham transcranial direct current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Bone Marrow Transplantation in Treating Patients With Leukemia, Myelodysplasia, or Lymphoblastic Lymphoma
Status: COMPLETED
Conditions: Leukemia|Lymphoma|Myelodysplastic Syndromes
Interventions: BIOLOGICAL: filgrastim|DRUG: cyclophosphamide|DRUG: cyclosporine|DRUG: cytarabine|DRUG: methotrexate|DRUG: methylprednisolone|PROCEDURE: allogeneic bone marrow transplantation|PROCEDURE: in vitro-treated bone marrow transplantation|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Novel Rigidizing Overtube in Colonic Endoscopic Submucosal Dissection
Status: RECRUITING
Conditions: Gastrointestinal Neoplasm
Interventions: PROCEDURE: Endoscopic Submucosal Dissection|DEVICE: Novel Rigidizing Overtube
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study to Compare the Relative Bioavailability of Two AG-881 Formulations and Evaluate the Effect of Food and Omeprazole on the Pharmacokinetics of AG-881
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: AG881 Formulation 1|DRUG: AG881 Formulation 2|DRUG: Omeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination of Diet and Oral Budesonide for Ulcerative Colitis
Status: RECRUITING
Conditions: Ulcerative Colitis|Ulcerative Colitis Chronic Mild|Ulcerative Colitis Chronic Moderate
Interventions: OTHER: Ulcerative colitis Exclusion Diet|OTHER: Partial enteral nutrition (PEN)|OTHER: free diet|DRUG: Oral Budesonide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Prime-Boost Dose Scheduling Trial for Human GM-CSF Gene Transduced Irradiated Prostate Allogeneic Cancer Cell Vaccines (Allogeneic Prostate GVAX®)
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: BIOLOGICAL: Immunotherapy allogeneic GM-CSF secreting cellular vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Real-World Study on CDK4/6 Inhibitors Combined With Endocrine Therapy and Subsequent Treatment in HR+/HER2- MBC.
Status: NOT_YET_RECRUITING
Conditions: Breast Cancer|Endocrine Therapy|CDK4/6 Inhibitors|Subsequent Treatment
Interventions: DRUG: Different treatment regimens following progression on CDK4/6 inhibitors.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety of Pitolisant in Pediatric Narcoleptic Patients With or Without Cataplexy, Double-blind Study Followed by a Prolonged Open-label Period
Status: ACTIVE_NOT_RECRUITING
Conditions: Narcolepsy With Cataplexy|Narcolepsy Without Cataplexy
Interventions: DRUG: pitolisant|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Expressive Storytelling to Share Adolescents/Young Adults Cancer Stories
Status: COMPLETED
Conditions: Pediatric Cancer|Growth, Posttraumatic|Nurse-Patient Relations|Narrative Medicine
Interventions: BEHAVIORAL: Nurse-patient dyadic storytelling intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of the Consumption of a Fermented Milk Enriched With Plant Sterols
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DIETARY_SUPPLEMENT: 1- plain low-fat dairy fermented product (drinkable) enriched with plant sterols-esters (1,6g /day equivalent as free sterols).|DIETARY_SUPPLEMENT: 2- plain low-fat dairy fermented product (drinkable) without plant sterols-esters
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Structural Fat Grafting for Craniofacial Trauma Using Manual Technique for Processing Fat Graft Material
Status: COMPLETED
Conditions: Facial Injuries
Interventions: PROCEDURE: Fat Grafting|DRUG: General Anesthesia|DEVICE: Coleman Cannulas|OTHER: Tefla non-adherent gauze pad
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Visual Rehabilitation Through Acoustic Biofeedback With Retimax Vision Trainer in Patients With Advanced Age-related Macular Degeneration
Status: COMPLETED
Conditions: Macular Degeneration Advanced|Macular Degeneration, Senile|Macular Degeneration, Dry|Macular Scar|Macular Degeneration Nonexudative
Interventions: DEVICE: Retimax Vision Trainer
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Exercise on Diastasis Rectus Abdominus
Status: TERMINATED
Conditions: Diastasis Recti and Weakness of the Linea Alba
Interventions: OTHER: Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of MTA and PRF Application in Periapical Lesions
Status: COMPLETED
Conditions: Apical Periodontitis|Wound Heal
Interventions: PROCEDURE: control group|PROCEDURE: MTA group|PROCEDURE: PRF group|PROCEDURE: MTA + PRF group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Heat-clearing and Blood-activating Chinese Medicinal Components in Acute Cerebral Infarction
Status: UNKNOWN
Conditions: Ischemic Stroke
Interventions: DRUG: Ixeris of sonchifolia Hance|DRUG: Panax notoginseng saponins|DRUG: Ixeris of sonchifolia Hance combined with Panax notoginseng saponins
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: AI Support in Novice's Decision-making for Ultrasound Fetal Weight Estimation
Status: ENROLLING_BY_INVITATION
Conditions: Fetal Weight|Ultrasound
Interventions: BEHAVIORAL: Artificial Intelligence feedback for ultrasound EFW standard plane images
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Nivolumab, Ipilimumab and Chemoradiation in Treating Patients With Resectable Gastric Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Clinical Stage 0 Gastric Cancer AJCC v8|Clinical Stage 0 Gastroesophageal Junction Adenocarcinoma AJCC v8|Clinical Stage I Gastric Cancer AJCC v8|Clinical Stage I Gastroesophageal Junction Adenocarcinoma AJCC v8|Clinical Stage IIB Gastric Cancer AJCC v8|Clinical Stage IIB Gastroesophageal Junction Adenocarcinoma AJCC v8|Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8|Clinical Stage IVA Gastric Cancer AJCC v8|Clinical Stage IVA Gastroesophageal Junction Adenocarcinoma AJCC v8|Gastric Adenocarcinoma|Localized Gastric Carcinoma|Localized Gastroesophageal Junction Adenocarcinoma|Pathologic Stage 0 Gastric Cancer AJCC v8|Pathologic Stage 0 Gastroesophageal Junction Adenocarcinoma AJCC v8|Pathologic Stage I Gastric Cancer AJCC v8|Pathologic Stage IA Gastric Cancer AJCC v8|Pathologic Stage IA Gastroesophageal Junction Adenocarcinoma AJCC v8|Pathologic Stage IB Gastric Cancer AJCC v8|Pathologic Stage IB Gastroesophageal Junction Adenocarcinoma AJCC v8|Pathologic Stage IC Gastroesophageal Junction Adenocarcinoma AJCC v8|Pathologic Stage II Gastroesophageal Junction Adenocarcinoma AJCC v8|Pathologic Stage IIA Gastric Cancer AJCC v8|Pathologic Stage IIA Gastroesophageal Junction Adenocarcinoma AJCC v8|Pathologic Stage IIB Gastric Cancer AJCC v8|Pathologic Stage IIB Gastroesophageal Junction Adenocarcinoma AJCC v8|Pathologic Stage IIIA Gastric Cancer AJCC v8|Pathologic Stage IIIB Gastroesophageal Junction Adenocarcinoma AJCC v8|Pathologic Stage IVA Gastroesophageal Junction Adenocarcinoma AJCC v8
Interventions: DRUG: Fluorouracil|RADIATION: Intensity-Modulated Radiation Therapy|BIOLOGICAL: Ipilimumab|BIOLOGICAL: Nivolumab|DRUG: Oxaliplatin|PROCEDURE: Therapeutic Conventional Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Momordica Charantia and Dihydroartemisinin-piperaquined-primaquine for Uncomplicated Plasmodium Falciparum Malaria Patients in Southwest Sumba Regency
Status: COMPLETED
Conditions: Uncomplicated Plasmodium Falciparum
Interventions: DRUG: Dihydroartemisinin|DRUG: Piperaquine|DRUG: Primaquine|DRUG: Momordica Charantia Extract
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Improving Drug Adherence Among Adolescents in Uganda Using SMS Reminders
Status: COMPLETED
Conditions: Human Immunodeficiency Virus
Interventions: BEHAVIORAL: Two-way SMS intervention|BEHAVIORAL: One-way SMS intervention group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study to Evaluate Optimized Retreatment and Prolonged Therapy With Bortezomib
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: bortezomib (optimized retreatment)|DRUG: dexamethasone (optimized retreatment)|DRUG: bortezomib (standard retreatment)|DRUG: dexamethasone (standard retreatment)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Evaluate Pharmacokinetics,Safety and Immunogenicity of Single Injection of CDP1 to Healthy Volunteers Compared to Erbitux
Status: UNKNOWN
Conditions: Healthy Volunteers
Interventions: DRUG: anti-EGFR monoclonal antibody|DRUG: Cetuximab injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of PP4001 for the Treatment of Symptoms Associated With Uncomplicated Urinary Tract Infection
Status: COMPLETED
Conditions: Urinary Tract Infection
Interventions: DRUG: PP4001|DRUG: PP4001|DRUG: PP4001|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Clinical Outcomes in Closure of Deep Neck Space Infection Incisions
Status: WITHDRAWN
Conditions: Deep Neck Space Infections
Interventions: PROCEDURE: neck incisions closed at bedside at the time of drain removal under local anesthesia|PROCEDURE: standard treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A 72-week Randomized Clinical Trial Comparing the Safety and Efficacy of Three Initial Antiretroviral Regimens -GPO-VIR S (d4T/3TC/NVP) for 24 Weeks Followed by GPO-VIR Z (AZT/3TC/NVP) vs GPO-VIR Z vs TDF/FTC/NVP
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: AZT/3TC/NVP, AZT/D4T/NVP, Truvada/NVP|DRUG: AZT/3TC/NVP, AZT/D4T/NVP, Truvada/NVP|DRUG: AZT/3TC/NVP, AZT/D4T/NVP, Truvada/NVP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Double-blind Trial to Study the Benefit of Colchicine in Patients With Acutely Decompensated Heart Failure
Status: COMPLETED
Conditions: HEART FAILURE
Interventions: DRUG: Colchicine 0.5 MG|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Theophylline Nasal Spray for PD-Related Hyposmia and Anosmia
Status: NOT_YET_RECRUITING
Conditions: Hyposmia|Anosmia
Interventions: DRUG: CYR-064
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gemcitabine/Oxaliplatin and Photodynamic Therapy in Cholangiocarcinoma
Status: WITHDRAWN
Conditions: Cholangiocarcinoma
Interventions: DRUG: Gemcitabine, Oxaliplatin, Photodynamic therapy (Photosan®)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Mesenchymal Precursor Cells in Diabetic Nephropathy
Status: COMPLETED
Conditions: Diabetic Nephropathy|Type 2 Diabetes
Interventions: BIOLOGICAL: Mesenchymal Precursor Cells (MPCs)|BIOLOGICAL: Mesenchymal Precursor Cells (MPCs)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Nutritional Formula Supplementation on Growth Rate of Growth Hormone (GH) Treated Children With Growth Hormone Deficiency (GHD) After the Second Year of Therapy
Status: RECRUITING
Conditions: IGHD - Isolated Growth Hormone Deficiency|Growth Retardation
Interventions: DIETARY_SUPPLEMENT: Nutritional supplementation standardized formula|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Platelet Activation and Circadian Rhythms of Clotting-Fibrinolysis Factors in Patients With Sleep Apnea Syndrome
Status: UNKNOWN
Conditions: Sleep Apnea|Cardiovascular Diseases
Interventions: DEVICE: CPAP (Continuous Positive Airway Pressure)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: MIMA Pilot Study: MIcrostructure of the Medial Temporal Lobe in Early Alzheimer's Disease
Status: RECRUITING
Conditions: Alzheimer Disease, Early Onset
Interventions: DIAGNOSTIC_TEST: high-resolution diffusion MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect Of Early Versus Delayed Laparoscopic Cholecystectomy In Patients With Grade II Cholecystitis
Status: COMPLETED
Conditions: Cholecystitis
Interventions: PROCEDURE: Laparoscopic cholecystectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Amphotericin B to Treat Visceral Leishmaniasis in Brazilian Children
Status: COMPLETED
Conditions: Visceral Leishmaniasis
Interventions: DRUG: Meglumine antimoniate|DRUG: Amphotericin B-deoxycholate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Use of Lidocaine Gel Versus Subconjunctival Xylocaine Injection in Pterygium Excision
Status: RECRUITING
Conditions: Pterygium
Interventions: DRUG: OPHTESIC LIDOCAINE HYDROCHLORIDE 20MG/G|DRUG: Xylocaine with Epinephrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Semaglutide Therapy for Alcohol Reduction - Tulsa
Status: RECRUITING
Conditions: Alcohol Use Disorder
Interventions: DRUG: Semaglutide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Photobiomodulation Treatment in Individuals With Multiple Sclerosis:
Status: UNKNOWN
Conditions: Multiple Sclerosis
Interventions: RADIATION: Photobiomodulation in the sublingual region|RADIATION: Photobiomodulation in the spinal cord|RADIATION: Photobiomodulation in the radial artery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: KOrea Renal Biobank NEtwoRk System TOward NExt-generation Analysis
Status: RECRUITING
Conditions: Glomerular Disease|Minimal Change Disease|IgA Nephropathy|Membranous Nephropathy|Focal Segmental Glomerulosclerosis|Lupus Nephritis|Crescentic Glomerulonephritis
Interventions: OTHER: Kidney Biopsy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Research in Ethno-Medicine and Education (REMED)
Status: COMPLETED
Conditions: Cervical Cancer|Human Papilloma Virus|HPV|Human Papillomavirus Infection
Interventions: BEHAVIORAL: Cervical Cancer Prevention Education
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety Study of OSI-211 (Liposomal Lurtotecan) to Treat Recurrent Small Cell Lung Cancer
Status: COMPLETED
Conditions: SCLC|Carcinoma, Small Cell
Interventions: DRUG: OSI-211 (Liposomal Lurtotecan)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Appropriate Technology for Home-based Rehabilitation in Patients With Post-stroke Physical Dysfunction
Status: NOT_YET_RECRUITING
Conditions: Stroke
Interventions: OTHER: Home-based rehabilitation appropriate technology (S-HRAT) training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Clinical Performance Study Protocol for Therascreen® KRAS RGQ PCR Kit
Status: UNKNOWN
Conditions: Non-Small Cell Lung Cancer|Colorectal Cancer
Interventions: DIAGNOSTIC_TEST: therascreen® KRAS RGQ PCR Kit
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Nordic Pancreatic Cancer Trial (NorPACT) - 1
Status: ACTIVE_NOT_RECRUITING
Conditions: Pancreatic Cancer
Interventions: DRUG: 5-FU|DRUG: Oxaliplatine|DRUG: Irinotecan|PROCEDURE: Pancreatic surgery|DRUG: 5-FU|DRUG: Oxaliplatine|DRUG: Irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 3 Safety and Efficacy Study of Fovista® (E10030) Intravitreous Administration in Combination With Either Avastin® or Eylea® Compared to Avastin® or Eylea® Monotherapy
Status: TERMINATED
Conditions: Age-Related Macular Degeneration
Interventions: DRUG: E10030|DRUG: bevacizumab or aflibercept|DRUG: E10030 sham injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Re-challenge Pembrolizumab Study as a Second or Further Line in Patients With Advanced NSCLC
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DRUG: Pembrolizumab|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gene Therapy Using Anti-Her-2 Cells to Treat Metastatic Cancer
Status: TERMINATED
Conditions: Metastatic Cancer
Interventions: DRUG: in vitro tumor reactive, chimeric T cell receptor (CAR ) gene-transduced PBL plus IV aldesleukin|DRUG: Cyclophosphamide|DRUG: Fludarabine|DRUG: Mesna
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Study of Continuous Infusion of Remazolam in Mechanically Ventilated Patients in ICU
Status: UNKNOWN
Conditions: Intensive Care Unit|Mechanical Ventilation|Anesthesia|Liver Failure|Pharmacokinetics
Interventions: DRUG: Remimazolam 0.1mg/kg/h|DRUG: Remimazolam 0.3mg/kg/h|DRUG: Remimazolam 0.5mg/kg/h
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ketamine-assisted Therapy for Patients With Pancreatic Ductal Adenocarcinoma
Status: RECRUITING
Conditions: Pancreatic Ductal Adenocarcinoma|Pain, Acute
Interventions: DRUG: Ketamine|DRUG: Ketamine Injectable Product|BEHAVIORAL: Meaning and Purpose therapy|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Long-Term Extension Study of Vedolizumab in Children and Teenagers With Ulcerative Colitis (UC) or Crohn's Disease (CD)
Status: NOT_YET_RECRUITING
Conditions: Ulcerative Colitis|Crohn's Disease
Interventions: DRUG: Vedolizumab SC|OTHER: No Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Alpha-1 Antitrypsin (AAT) Enhances Islet Autograft Survival in Patients With Chronic Pancreatitis
Status: COMPLETED
Conditions: Chronic Pancreatitis
Interventions: DRUG: Prolastin-C|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Testing TH-302, in Combination With Preoperative Chemoradiotherapy, in Esophageal Cancer.
Status: WITHDRAWN
Conditions: Esophageal Cancer
Interventions: DRUG: TH-302|OTHER: HX4 scan|DRUG: Carboplatin|DRUG: Paclitaxel|RADIATION: Radiotherapy|PROCEDURE: surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Safety of Autologous Lyophilized Plasma Versus Fresh Frozen Plasma in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: BIOLOGICAL: Lyophilized Plasma|OTHER: Fresh Frozen Plasma
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Stem Cell Transplant From Donors After Alpha Beta Cell Depletion in Children and Adults With T-allo10 Cells Addback
Status: RECRUITING
Conditions: Hematologic Diseases
Interventions: BIOLOGICAL: Allogeneic Stem Cell Transplant|DEVICE: CliniMACS Prodigy System|DRUG: T-allo10 cells addback
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Safety, Tolerability And Actual Use Study Of Bococizumab And An Autoinjector (Pre-Filled Pen) In Subjects With Hyperlipidemia Or Dyslipidemia
Status: COMPLETED
Conditions: Hyperlipidemia
Interventions: BIOLOGICAL: Bococizumab 150mg|BIOLOGICAL: Bococizumab 75mg|BIOLOGICAL: Bococizumab 150mg placebo|BIOLOGICAL: Bococizumab 75mg placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: African American Children, Glycemic Control, and Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes|Vitamin D Deficiency
Interventions: DIETARY_SUPPLEMENT: Vitamin D2|OTHER: Sugar pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy in Treating Young Patients With Relapsed or Refractory Acute Leukemia
Status: COMPLETED
Conditions: Leukemia
Interventions: BIOLOGICAL: filgrastim|DRUG: clofarabine|DRUG: dexamethasone|DRUG: thiotepa|DRUG: topotecan hydrochloride|DRUG: vinorelbine tartrate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ranolazine Cardioprotection in PCI
Status: TERMINATED
Conditions: Acute Coronary Syndrome
Interventions: DRUG: Ranolazine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Persona Partial Knee Study
Status: ENROLLING_BY_INVITATION
Conditions: Arthroplasty, Replacement, Knee
Interventions: DEVICE: Stryker Triathlon total knee replacement|DEVICE: Zimmer Biomet Persona Partial Knee unicondylar knee replacement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Bright Light Treatment On Elders In a Long Term Care Environment
Status: COMPLETED
Conditions: Behavioral Responses to Bright Light Therapy in Elders
Interventions: OTHER: exposure to bright light|OTHER: low luminosity red light
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety/Efficacy Study of CID-078 in Patients With Advanced Solid Tumor Malignancies
Status: RECRUITING
Conditions: Advanced Solid Tumor|Metastatic Solid Tumor|Refractory Solid Tumor|Cancer|Lung Cancer|Triple Negative Breast Cancer|Breast Neoplasms|Neuroendocrine Tumors|Neuroendocrine Carcinoma
Interventions: DRUG: CID-078 Monotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Placebo Controlled Study to Generate Data Characterising Clinical Events, Physiological Responses and Immune Responses
Status: COMPLETED
Conditions: Safety Markers of Adjuvanted Influenza Vaccine
Interventions: BIOLOGICAL: Fluad|BIOLOGICAL: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of a Large Protein Molecule Administered With Escalating Doses of Recombinant Human Hyaluronidase
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: large protein molecule
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Botulinum Toxin A In Patients With Excessive Gingival Display With And Without Zinc Supplementation
Status: COMPLETED
Conditions: Excessive Gingival Display
Interventions: DRUG: Botulinum toxin type A|DIETARY_SUPPLEMENT: Zinc supplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Exploratory Study of Advanced Breast Cancer in HER2 Positive Patients With Failure of Multi-line Therapy Treated by Combination of Inetetamab (Cipterbin) + PD-1 Inhibitor Combined With Utidelone.
Status: ACTIVE_NOT_RECRUITING
Conditions: HER2 Positive Metastatic Breast Cancer
Interventions: DRUG: inetetamab and PD-1 inhibitor combined with chemotherapy.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Body Composition Assessment and Smart-phone Based Counselling on Healthy Eating and Weight Management
Status: UNKNOWN
Conditions: Weight Management|Healthy Diet
Interventions: BEHAVIORAL: Body composition assessment and smart-phone based counselling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Phase I Trial of Docetaxel With Perifosine
Status: COMPLETED
Conditions: Neoplasms
Interventions: DRUG: Perifosine|DRUG: Docetaxel|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of CareMin650 for Prevention of Oral Mucositis in HNC Patients Starting Radiotherapy
Status: COMPLETED
Conditions: Head and Neck Cancer|Oral Mucositis (Ulcerative) Due to Radiation|Radiation Therapy Complication
Interventions: DEVICE: Photobiomodulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Venous Leg Ulcer and Lymphedema Registry
Status: ENROLLING_BY_INVITATION
Conditions: Venous Stasis Ulcer|Quality of Patient Care
Interventions: BIOLOGICAL: cellular and tissue based therapy|PROCEDURE: debridement|PROCEDURE: advanced wound therapy|DIETARY_SUPPLEMENT: Nutritional screening
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Investigation of the Postprandial Response of Two Different PDO Cheeses on Metabolic Biomarkers
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: Authentic Ladotyri Mytilinis PDO cheese|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: A Phase 2 Study to Evaluate the Safety and Immunogenicity of Two Oral Poliovirus Vaccine Candidates
Status: COMPLETED
Conditions: Poliomyelitis
Interventions: BIOLOGICAL: Novel OPV2 candidate 1|BIOLOGICAL: Novel OPV2 candidate 2|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Randomized Study of the Efficacy of Low Venous Pressure General Anesthesia Versus Combined Spinal-Epidural Anesthesia in Decreasing Blood Loss During Prostate Surgery
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: PROCEDURE: low venous pressure general anesthesia|PROCEDURE: combined spinal-epidural anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety and Tolerability of AZD1656 in Type 2 Diabetes Mellitus (T2DM) Patients Treated With Metformin and Sulfonylurea
Status: COMPLETED
Conditions: Type II Diabetes Mellitus
Interventions: DRUG: AZD1656|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Multifocal Brain Magnetic Stimulation in Chronic Ischemic Stroke
Status: COMPLETED
Conditions: Stroke
Interventions: DEVICE: repetitive Transcranial Magnetic Stimulation -On|DEVICE: repetitive Transcranial Magnetic Stimulation -Off
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Piloting At-birth Point of Care HIV Testing Strategies in Kenya
Status: COMPLETED
Conditions: HIV Infections
Interventions: BEHAVIORAL: Alere q HIV-1/2 Detect for point of care infant testing|BEHAVIORAL: GeneXpert HIV-1 Qual for point of care infant testing|BEHAVIORAL: HIV DNA PCR testing (Standard of Care)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety and Early Signs of Efficacy of IL12-L19L19.
Status: RECRUITING
Conditions: Advanced Solid Tumor|Metastatic Solid Tumor
Interventions: DRUG: IL12-L19L19|DRUG: IL12-L19L19
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intracavernous Bone Marrow Stem-cell Injection for Post Prostatectomy Erectile Dysfunction
Status: COMPLETED
Conditions: Prostate Cancer|Erectile Dysfunction
Interventions: BIOLOGICAL: injection of bone marrow mononucleated cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Is Thoracic Paravertebral Block a Better Option Than Conscious Sedation for PRFA of Liver Tumors
Status: COMPLETED
Conditions: Liver Tumor
Interventions: PROCEDURE: thoracic paravertebral blockade|PROCEDURE: local anaesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Electroacupuncture in the Treatment of Diabetic Peripheral Neuropathy
Status: NOT_YET_RECRUITING
Conditions: Diabetic Peripheral Neuropathic Pain
Interventions: PROCEDURE: Basal therapy+EA|OTHER: Basal therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy in Treating Patients With Recurrent or Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: FOLFOX regimen|DRUG: fluorouracil|DRUG: leucovorin calcium|DRUG: oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: To Evaluate the Safety and Efficacy of a New Device in the Management of Mild to Moderate Atopic Dermatitis in Children
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DEVICE: F# 11054-010|DEVICE: F# 10495-053
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Compare the Effectiveness of Adductor Canal Pain Catheters Following Total Knee Arthroplasty
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: DRUG: Ropivacaine Continuous Infusion|DRUG: Ropivacaine Intermittent Bolus|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Study of a Vaccine Against Meningitis in Infants (2,4 & 6 Months Age) After a Birth Dose of Hepatitis B.
Status: COMPLETED
Conditions: Hepatitis B|Diphtheria|Whole Cell Pertussis|Tetanus|Haemophilus Influenzae Type b
Interventions: BIOLOGICAL: Tritanrix-HepB/Meningitec conjugate vaccine|BIOLOGICAL: Tritanrix/Hiberix vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: |Primary Purpose: PREVENTION
Clinical trial: Accupressure of P6 to Reduce Nausea During Cesarean Section
Status: COMPLETED
Conditions: Pregnancy Related|Cesarean Delivery|Nausea|Vomiting
Interventions: OTHER: Magnet at P6|OTHER: Magnet applied to arm not at P6 pressure point.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Assessment Of Safety And Efficacy Of SU11248 In Patients With Metastatic Colorectal Cancer Who Have Failed Selected Previous Treatments.
Status: COMPLETED
Conditions: Colorectal Neoplasms
Interventions: DRUG: SU011248
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Empagliflozin on Exercise Capacity and Left Ventricular Diastolic Function in Patients With Heart Failure With Preserved Ejection Fraction and Type-2 Diabetes Mellitus
Status: COMPLETED
Conditions: Heart Failure, Diastolic|Diabetes Mellitus, Type 2
Interventions: DRUG: Empagliflozin|OTHER: Standard care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT