pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Ventilator Hyperinflation and Hemodynamics
Status: COMPLETED
Conditions: Respiratory Failure|Respiratory Disorders
Interventions: DEVICE: Baseline Mechanical Ventilation|DEVICE: VHI With Inspiratory Pause|DEVICE: VHI Without Inspiratory Pause
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Therapeutic Light on Sleep, Circadian Rhythm, and Global Function in Women With Alzheimer's
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DEVICE: Morning Simulated Sunlight|DEVICE: Non-therapeutic Red Light
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy Study of FANG(30) for Active Rheumatoid Arthritis in Adult Patients
Status: COMPLETED
Conditions: Arthritis, Rheumatoid
Interventions: DRUG: FANG(30)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of the Estech COBRA® Surgical System to Treat Patients With a History of Irregular Heart Beats
Status: TERMINATED
Conditions: Persistent Atrial Fibrillation
Interventions: DEVICE: The Estech COBRA® Surgical System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Abdominal Binders and TENS on Puerperium Period After Cesarean Section
Status: COMPLETED
Conditions: Cesarean Section; Complications, Wound, Dehiscence
Interventions: OTHER: ABDOMINAL BINDERS|OTHER: TENS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: How Phenotypical Characteristics of Woebot Users Are Related to Clinical Outcomes
Status: COMPLETED
Conditions: To Understand the Characteristics of Digital Mental Health Intervention Users as They Relate to Mental Health Outcomes
Interventions: DEVICE: WB-LIFE
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Topical 5% Tranexamic Acid as a Treatment for Postinflammatory Hyperpigmentation Due to Acne Vulgaris
Status: WITHDRAWN
Conditions: Postinflammatory Hyperpigmentation
Interventions: DRUG: Tranexamic Acid|DRUG: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ca-Mg Butyrate in GWI
Status: RECRUITING
Conditions: Gulf War Illness|Chronic Fatigue|Neurocognitive Dysfunction
Interventions: DRUG: Cal-Mag Butyrate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Food Effects on the Relative Bioavailability of Different Dosages of Risedronate
Status: COMPLETED
Conditions: Postmenopausal|Non-lactating|Surgically Sterile
Interventions: DRUG: risedronate|DRUG: risedronate|DRUG: risedronate|DRUG: risedronate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: A Phase 1 Study of Safety and Bioactivity With FG-3019 in Combination With Gemcitabine and Erlotinib for Subjects With Locally Advanced or Metastatic Pancreatic Cancer
Status: COMPLETED
Conditions: Locally Advanced or Metastatic Pancreatic Cancer
Interventions: DRUG: FG-3019
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Combined Strategy Addressed to Practitioners and Chronic Obstructive Pulmonary Disease (COPD) Patients to Improve Clinical Control and Quality of Life
Status: UNKNOWN
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: OTHER: Implementation of Clinical Practice Guidelines (GPC) and Health Education Program
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Flavopiridol and Paclitaxel in Treating Patients With Locally Advanced or Metastatic Esophageal Cancer That Has Not Responded to Previous Paclitaxel
Status: COMPLETED
Conditions: Esophageal Cancer
Interventions: DRUG: alvocidib|DRUG: paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Double-blind Placebo Controlled Study of Oxytocin in Fragile X Syndrome
Status: COMPLETED
Conditions: Fragile X Syndrome
Interventions: DRUG: placebo|DRUG: oxytocin 24IU|DRUG: oxytocin 48IU
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Open or Keyhole Surgery Through the Chest for Newborn Babies: Effect on Blood Gases
Status: COMPLETED
Conditions: Esophageal Atresia With Tracheo-esophageal Fistula|Congenital Diaphragmatic Hernia
Interventions: PROCEDURE: Hypercapnia during thoracoscopy|PROCEDURE: Open surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study of Chemo-prevention of Green Tea in Women With Ductal Carcinoma in Situ
Status: TERMINATED
Conditions: Ductal Carcinoma in Situ
Interventions: DRUG: Polyphenon E
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety/Efficacy Study of Imprime PGG With Cetuximab in Patients With Recurrent/Progressive Colorectal Carcinoma
Status: COMPLETED
Conditions: Recurrent Colorectal Carcinoma|Progressive Colorectal Carcinoma
Interventions: BIOLOGICAL: Safety and efficacy of escalating doses|BIOLOGICAL: Safety and efficacy of escalating doses.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Retarded Phosphatidylcholine in Steroid-Dependent Chronic Active Ulcerative Colitis
Status: COMPLETED
Conditions: Ulcerative Colitis|Phosphatidylcholine
Interventions: DRUG: Retarded Release Phosphatidylcholine (rPC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Phase II Study of DA-3031(PEG-G-CSF) in Chemotherapy-induced Neutropenia
Status: COMPLETED
Conditions: Chemotherapy Induced Neutropenia
Interventions: DRUG: PEG-G-CSF|DRUG: G-CSF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunologic Effects of HCV Therapy With HARVONI in HCV Genotype 1 Chronically Mono-infected Active and Former IDUs
Status: COMPLETED
Conditions: Hepatitis C
Interventions: DRUG: Harvoni (Fixed dose combination ledipasvir/sofosbuvir)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Graphene Oxide in the Surgical Management of Intrabony Periodontal Defects
Status: UNKNOWN
Conditions: Periodontal Diseases
Interventions: PROCEDURE: Graphene oxide and open flap debridement|PROCEDURE: Open flap debridement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: INTEGRA Study: Primary Care Intervention in Type 2 Diabetes Patients With Poor Glycaemic Control
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: OTHER: Intervention 1|OTHER: Intervention 2
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effect of Action Observation and Motor Imagery on Arthrogenic Muscle Inhibition of the Quadriceps in Patients With End-stage Knee Gonarthrosis.
Status: RECRUITING
Conditions: Knee Osteoarthritis|Arthrogenic Muscle Inhibitions
Interventions: OTHER: AOT + MI|OTHER: Control AOT + MI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Linaclotide Safety and Efficacy in 2 to 5-Year-Old Participants With Functional Constipation
Status: COMPLETED
Conditions: Functional Constipation
Interventions: DRUG: Linaclotide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cerebrospinal Fluid Drainage (CSFD) in Acute Spinal Cord Injury
Status: COMPLETED
Conditions: Spinal Cord Injury
Interventions: PROCEDURE: CSFD and elevation of MAP|PROCEDURE: Maintenance of MAP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hyaluronic Acid-containing Artificial Tears in Post-cataract Surgery Dry Eye Disease
Status: COMPLETED
Conditions: Dry Eye Disease|Cataract
Interventions: DRUG: Systane HYDRATION® Preservative-Free Lubricant Eye Drops|DRUG: Optive Fusion® Lubricant Eye Drops (Unit Dose)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Talazoparib Before Standard Therapy in Treating Patients With Invasive, BRCA-Mutated Breast Cancer
Status: COMPLETED
Conditions: Breast Adenocarcinoma|Deleterious BRCA1 Gene Mutation|Deleterious BRCA2 Gene Mutation|HER2/Neu Negative|Invasive Breast Carcinoma
Interventions: OTHER: Laboratory Biomarker Analysis|DRUG: Talazoparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dropless vs. Standard Drops Contralateral Eye Study
Status: COMPLETED
Conditions: Cataract
Interventions: DRUG: TriMoxiVanc|DRUG: Moxifloxacin HCl 0.5%|DRUG: Ilevro|DRUG: Prednisolone acetate 1%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of the Efficacy of Kalinox® 170 Bar in Adult Oncology
Status: COMPLETED
Conditions: Cancer|Pain
Interventions: DRUG: 50% Oxygen/50% Nitrous oxide premix (Kalinox 170 bar)|DRUG: 50% Oxygen/50% Nitrogen premix
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Eight Weeks Sofosbovir/Ledipasvir in HCV Infected Children Aged 4 to 10 Years
Status: COMPLETED
Conditions: Hepatitis C, Chronic|Children, Only
Interventions: DRUG: Sofosbovir/Lepipasvir (200/45mg) tablet (Heterosofir)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sitafloxacin-containing Regimens for Shortening Tuberculosis Treatment
Status: NOT_YET_RECRUITING
Conditions: Tuberculosis, Pulmonary
Interventions: DRUG: Sitafloxacin|DRUG: SMZ/TMP|DRUG: Rifampin|DRUG: Pyrazinamide|DRUG: Rifapentine|DRUG: Isoniazid|DRUG: Ethambutol|DRUG: Moxifloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TILs & Low-Dose IL-2 Therapy Following Cyclophosphamide and Fludarabine in Pleural Mesothelioma Patients
Status: COMPLETED
Conditions: Pleural Mesothelioma
Interventions: DRUG: Cyclophosphamide|DRUG: Fludarabine|BIOLOGICAL: Autologous tumor infiltrating lymphocytes (TILs)|BIOLOGICAL: Interleukin-2
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Expanding Paramedicine in the Community
Status: COMPLETED
Conditions: Diabetes Mellitus (DM)|Congestive Heart Failure (CHF)|Chronic Obstructive Pulmonary Disease (COPD)
Interventions: OTHER: Community Paramedicine|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Colloid Infusion for Optimal Outcomes In Non-cardiac Surgery (COIN Trial)
Status: RECRUITING
Conditions: Postoperative Complications
Interventions: DRUG: Hydroxyethyl Starch 130/0.4 and Electrolyte injection of 5ml/kg|DRUG: Multiple Electrolytes injection of 5 ml/kg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Immunogenicity and Safety Evaluation of Recombinant Novel Coronavirus Vaccine (CHO Cells) in Enhancing Immunity
Status: COMPLETED
Conditions: Coronavirus Disease 2019
Interventions: BIOLOGICAL: Recombinant new coronavirus vaccine (CHO cell) group
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study on the Reapplication of Chloraprep After Lower Extremity Surgery and Prior to Dressing Application
Status: UNKNOWN
Conditions: Lower Extremity Surgery|Surgical Site Infection|Bacterial Colonization|Surgical Antiseptic
Interventions: DRUG: Chloraprep
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of Markers of Glucocorticoid Effects in Patients With Addisons Disease (DOSCORT)
Status: UNKNOWN
Conditions: Addison Disease
Interventions: DRUG: Betamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Tolvaptan in Subjects With Chronic Kidney Disease Between Late Stage 2 to Early Stage 4 Due to Autosomal Dominant Polycystic Kidney Disease
Status: COMPLETED
Conditions: Chronic Kidney Disease|Autosomal Dominant Polycystic Kidney Disease
Interventions: DRUG: Tolvaptan (OPC-41061)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy in Adult Subjects With Acute Migraines
Status: COMPLETED
Conditions: Migraine, With or Without Aura
Interventions: DRUG: Rimegepant|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Individualizing Dual Antiplatelet Therapy After Percutaneous Coronary Intervention - The IDEAL-PCI Registry
Status: COMPLETED
Conditions: Platelet Inhibition|Coronary Stent Implantation
Interventions: DRUG: prasugrel or ticagrelor|DRUG: Clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Web-Prolonged Exposure (Web-PE) and Present-Centered Therapy (PCT) for PTSD Among Active-Duty Military Personnel
Status: COMPLETED
Conditions: Posttraumatic Stress Disorders|Combat Disorders
Interventions: OTHER: Web-PE Therapy|OTHER: Therapist-Delivered Present-Centered Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use of ACA 125 in Patients With Ovarian Cancer: Safety and Immune Response
Status: COMPLETED
Conditions: Ovarian Cancer|Fallopian Tube Neoplasms|Peritoneal Neoplasms
Interventions: BIOLOGICAL: ACA 125
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Treatment of Breast Cancer-related Lymphedema With a Negative Pressure Device
Status: COMPLETED
Conditions: Lymphedema, Secondary|Lymphedema of Upper Limb
Interventions: DEVICE: PhysioTouch|OTHER: Manual Lymph Drainage (MLD)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Open-label, Single Arm, Phase 2 Study to Evaluate ABT-450/r/ABT-267 and ABT-333 With Ribavirin (RBV) in Adults With Genotype 1 HCV Infection Taking Methadone or Buprenorphine
Status: COMPLETED
Conditions: Chronic Hepatitis C Infection|Chronic Hepatitis C
Interventions: DRUG: ABT-450/r/ABT-267|DRUG: ABT-333|DRUG: Ribavirin (RBV)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Appropriate Anticoagulation Duration for Chronic Obstructive Pulmonary Disease With Pulmonary Thromboembolism
Status: UNKNOWN
Conditions: COPD Exacerbation|PTE - Pulmonary Thromboembolism
Interventions: DRUG: Warfarin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Amino Acid Formulation on Healthy Men Undergoing Unilateral Knee Immobilization
Status: COMPLETED
Conditions: Muscle Atrophy
Interventions: DIETARY_SUPPLEMENT: Amino Acid|DEVICE: Breg Brace single-leg immobilization|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Evaluate the Efficacy and Safety of LASN01 in Patients With Thyroid Eye Disease
Status: RECRUITING
Conditions: Thyroid Eye Disease|Eye Diseases|Graves Ophthalmopathy|Graves Orbitopathy|Thyroid Associated Ophthalmopathy|Endocrine System Diseases|Orbital Diseases|Proptosis
Interventions: DRUG: LASN01|DRUG: LASN01|DRUG: Placebo|DRUG: LASN01
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Sucrosomial Iron vs. Oral Iron Sulfate for the Treatment of Iron Deficiency Anemia in Patients With Ulcerative Colitis
Status: RECRUITING
Conditions: Anemia, Iron Deficiency|Ulcerative Colitis
Interventions: DRUG: Sucrosomial Iron|DRUG: Oral Iron
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Radiotherapy Combined With TKI and Anti-PD-1 Antibody for Stage IIIA Hepatocellular Carcinoma
Status: RECRUITING
Conditions: Stage IIIA Hepatocellular Carcinoma
Interventions: COMBINATION_PRODUCT: Radiotherapy combined with TKI and Anti-PD-1 Antibody
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PPV With Internal Limiting Membrane Peeling for Treatment-Naïve DME
Status: COMPLETED
Conditions: Diabetic Retinopathy|Macular Edema
Interventions: PROCEDURE: PPV/MP|DRUG: Intravitreal injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Aggressive Localized Lymphoma
Status: TERMINATED
Conditions: B Cell Lymphoma
Interventions: DRUG: rituximab|DRUG: doxorubicin|DRUG: vincristine|DRUG: prednisone|PROCEDURE: radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Surgery Induced Trauma After Total Versus Medial Unicompartmental Knee Arthroplasty (SITA)
Status: RECRUITING
Conditions: Knee Osteoarthritis|Arthritis|Surgery|Total Knee Arthroplasty|Unicompartmental Knee Arthroplasty
Interventions: PROCEDURE: Total Knee Arthroplasty (TKA)|PROCEDURE: Unicompartmental Knee Arthroplasty (UKA)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Sodium Concentration of Priming and Rinsing Fluids on Weight Gain
Status: COMPLETED
Conditions: Fluid Overload and Hypertension in Hemodialysis Patients
Interventions: OTHER: 5% dextrose solution
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nurse Navigation Versus Current Care Coordination During Colorectal Cancer Trajectories
Status: COMPLETED
Conditions: Self Efficacy|Continuity of Care|Quality of Life|Colorectal Neoplasms|Case Management
Interventions: OTHER: Nurse navigation|OTHER: Current care coordination
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Perioperative Tonsillectomy Protocol Development
Status: UNKNOWN
Conditions: Tonsillitis
Interventions: DRUG: Acetaminophen|DRUG: Low-dose Dexamethasone|DRUG: Placebo Oral Tablet|DRUG: High-Dose Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Micronutrient Bioavailability From Wheat
Status: UNKNOWN
Conditions: Healthy
Interventions: OTHER: Bread product (standard milled)|OTHER: Bread Product (micro-milled)|OTHER: Bread Product (standard aleurone)|OTHER: Bread product (micro-milled aleurone)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Sleep Trial to Prevent Alzheimer's Disease
Status: RECRUITING
Conditions: Sleep|Alzheimer Disease
Interventions: DRUG: Suvorexant 20 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of a Gel Sunscreen in Controlled Use Conditions (208/2016)
Status: COMPLETED
Conditions: Sunscreening Agents
Interventions: DRUG: BAY987517|DRUG: BullFrog Gel Sunscreen Land Sport SPF-50
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluation of the SARC-F Score as a Screening Tool for Undernutrition in a Geriatric Population
Status: UNKNOWN
Conditions: Sarcopenia|Denutrition
Interventions: OTHER: SARC-F score, handgrip test and impedancemetry
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Early or Delayed Fludarabine and Rituximab in Treating Patients With Previously Untreated Chronic Lymphocytic Leukemia
Status: TERMINATED
Conditions: Leukemia
Interventions: BIOLOGICAL: rituximab|DRUG: fludarabine phosphate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Locomotor Muscle Oxygenation and Activation During Acute Interval Compared to Constant-load Bed-cycling Exercise
Status: RECRUITING
Conditions: Intensive Care Unit Acquired Weakness|Critical Illness
Interventions: OTHER: Constant-load bed-cycling exercise|OTHER: Interval bed-cycling exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacological Effects of Pascoflair® on Brain Activity in Patients Suffering From Test Anxiety
Status: COMPLETED
Conditions: Stress|Brain Activity|Passiflora Incarnata|Test Anxiety
Interventions: DRUG: Pascoflair|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ublituximab Followed by Response-driven Addition of Umbralisib for Treatment-naive Follicular or Marginal Zone Lymphoma
Status: COMPLETED
Conditions: Marginal Zone Lymphoma|Follicular Lymphoma
Interventions: DRUG: Ublituximab|DRUG: Umbralisib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Systems of Support (SOS) to Increase Colon Cancer Screening and Follow-up
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: BEHAVIORAL: Automated Mailing|BEHAVIORAL: Automated Mailing Plus Assisted|BEHAVIORAL: Auto Plus Assisted Plus Navigation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Comparison of Slow and Fast Transition From Stimulants to Atomoxetine in Children and Adolescents With Attention Deficit/Hyperactivity Disorder(ADHD)
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: DRUG: Atomoxetine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of TRF on Obese Patients With CKD Stage 3-4
Status: COMPLETED
Conditions: Time Restricted Feeding|Renal Insufficiency, Chronic|Obesity
Interventions: BEHAVIORAL: Time-restricted feeding(TRF)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Advanced Endoscopy During COVID-19
Status: COMPLETED
Conditions: Cholangitis, Secondary Biliary|Cholangiocarcinoma|Obstructive Jaundice|Pancreas Cancer|COVID-19|SARS-CoV-2
Interventions: OTHER: Endoscopic management according to standard of care
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Retinal Vascular Changes in Patients After Coronavirus Disease 2019 (COVID-19)
Status: ACTIVE_NOT_RECRUITING
Conditions: COVID-19
Interventions: DIAGNOSTIC_TEST: Central visual acuity|DIAGNOSTIC_TEST: Intraocular pressure measurement|DIAGNOSTIC_TEST: Slit lamp examination|DIAGNOSTIC_TEST: Retinal oximetry|DIAGNOSTIC_TEST: Optical coherence tomography and angiography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparing T-stenting And Minimal Protrusion With External Minicrush for Treatment of Complex Coronary Bifurcation
Status: RECRUITING
Conditions: Coronary Artery Disease|Ischemic Heart Disease|Chronic Coronary Syndrome|Acute Coronary Syndrome
Interventions: PROCEDURE: Percutaneous Coronary Intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Information Retention After Video (Augmented) Preoperative Anesthesiological Education
Status: COMPLETED
Conditions: Anesthesia|Education|Informed Consent|Anxiety|Multimedia
Interventions: DEVICE: Video education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Phase II Randomized, Double-Blind, Placebo-Controlled Study of Intravenous Mucoid Exopolysaccharide Pseudomonas Aeruginosa Immune Globulin for Cystic Fibrosis
Status: COMPLETED
Conditions: Cystic Fibrosis|Bacterial Infections
Interventions: DRUG: mucoid exopolysaccharide P. aeruginosa immune globulin IV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Study of Cabozantinib (XL184) vs Everolimus in Subjects With Metastatic Renal Cell Carcinoma
Status: COMPLETED
Conditions: Renal Cell Carcinoma
Interventions: DRUG: Cabozantinib tablets|DRUG: Everolimus (Afinitor) tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparison of 000-0551 Lotion Versus Vehicle Lotion in Subjects With Plaque Psoriasis (Study -305)
Status: COMPLETED
Conditions: Plaque Psoriasis
Interventions: DRUG: 000-0551 Lotion|DRUG: Vehicle Lotion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: IGIV Study for Chronic ITP Patients Ages 3-70
Status: COMPLETED
Conditions: Idiopathic Thrombocytopenic Purpura
Interventions: BIOLOGICAL: IGIV3I Grifols 10%
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Radspherin® in Patients With Primary Advanced Epithelial Cancer, With Peritoneal Metastasis That Are Homologous Recombination Proficient Scheduled to Undergo Neoadjuvant Chemotherapy and Interval Debulking Surgery
Status: RECRUITING
Conditions: Peritoneal Carcinomatosis|Ovarian Cancer
Interventions: DRUG: Radspherin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety Study of SHR-1819 Injection in Adult Patients With Severe Atopic Dermatitis
Status: COMPLETED
Conditions: Moderate to Severe Atopic Dermatitis
Interventions: DRUG: SHR1819|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Adoptive Cell Therapy With (LN-145) in Combination With Pembrolizumab in Treating Patients With Unresectable or Metastatic Transitional Cell Cancer Who Have Failed Cisplatin-Based Chemotherapy
Status: WITHDRAWN
Conditions: Metastatic Bladder Urothelial Carcinoma|Metastatic Renal Pelvis Urothelial Carcinoma|Metastatic Ureter Urothelial Carcinoma|Metastatic Urethral Urothelial Carcinoma|Unresectable Renal Pelvis Urothelial Carcinoma|Unresectable Ureter Urothelial Carcinoma
Interventions: DRUG: Cyclophosphamide|DRUG: Fludarabine|DRUG: Fludarabine Phosphate|BIOLOGICAL: Pembrolizumab|BIOLOGICAL: Autologous Tumor Infiltrating Lymphocytes LN-145|BIOLOGICAL: Aldesleukin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Perioperative Analgesia Between Intravenous Paracetamol and Fentanyl for Rigid Hysteroscopy
Status: COMPLETED
Conditions: Analgesia|Effect of Drug
Interventions: DRUG: paracetamol, the group P|DRUG: fentanyl, group-F administered as an active comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intercostal Nerve Cryotherapy in Patients Undergoing Minimally Invasive Pulmonary Resection
Status: ACTIVE_NOT_RECRUITING
Conditions: Cryotherapy Effect|Pain, Postoperative
Interventions: DEVICE: cryoanalgesia|OTHER: Standard of Care Pain Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study of Therapy With TransMID™ Compared to Best Standard of Care in Patients With Glioblastoma Multiforme
Status: WITHDRAWN
Conditions: Glioblastoma Multiforme
Interventions: DRUG: TransMID™
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endeavor Zotarolimus - Eluting Stent in the Treatment Lesions in Small Native Coronary Arteries.
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DEVICE: Endeavor Zotarolimus-Eluting Coronary Stent
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase II, Multicenter, Double Blind, Placebo-Controlled Safety, Tolerability Study of BMS-708163 in Patients With Mild to Moderate Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: BMS-708163|DRUG: BMS-708163|DRUG: BMS-708163|DRUG: BMS-708163|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Safety, Tolerability, and Efficacy of BIVV003 for Autologous Hematopoietic Stem Cell Transplantation in Patients With Severe Sickle Cell Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Sickle Cell Disease
Interventions: BIOLOGICAL: Plerixafor|DRUG: Busulfan|GENETIC: BIVV003
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Probiotics on Functional Constipation in Adults
Status: COMPLETED
Conditions: Functional Constipation
Interventions: DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: 3 Billion UFC strains of probiotics|DIETARY_SUPPLEMENT: 8 Billion UFC strains of probiotics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Wheat Bran Extract on Cognitive and Memory Function
Status: COMPLETED
Conditions: Cognitive Function 1, Social
Interventions: DIETARY_SUPPLEMENT: WBE|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety Study for Ecabet Ophthalmic Solution for Treating Dry Eye Syndrome
Status: COMPLETED
Conditions: Dry Eye Syndromes
Interventions: DRUG: Ecabet|DRUG: Ecabet|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Comparative Safety and Immunogenicity of 1.0 µg Intramuscular (i.m.) and 2.0 µg Subcutaneous (s.c.) Dosing With VAX102 (M2e-flagellin) Universal Influenza Vaccine in Healthy Adults
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: VAX102
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Intensity-Modulated Radiation Therapy and Paclitaxel With or Without Pazopanib Hydrochloride in Treating Patients With Anaplastic Thyroid Cancer
Status: COMPLETED
Conditions: Thyroid Gland Anaplastic Carcinoma
Interventions: RADIATION: Intensity-Modulated Radiation Therapy|DRUG: Paclitaxel|DRUG: Pazopanib Hydrochloride|OTHER: Placebo Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Naptumomab Estafenatox in Combination With Pembrolizumab Preceded by Obinutuzumab in Patients With Urothelial Cancers
Status: WITHDRAWN
Conditions: Urothelial Carcinoma
Interventions: DRUG: Naptumomab Estafenatox|DRUG: Pembrolizumab|DRUG: Obinutuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study Evaluating Beta Blockers Use and Fracture Risk in Patients With Primary Osteoporosis
Status: RECRUITING
Conditions: Beta Blocker Toxicity
Interventions: DRUG: nonselective beta blocker|DRUG: cardio-selective beta blocker group|DRUG: alendronate sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long-term Safety and Efficacy of GSK3196165 (Otilimab) in the Treatment of Rheumatoid Arthritis (RA)
Status: TERMINATED
Conditions: Arthritis, Rheumatoid
Interventions: BIOLOGICAL: Otilimab (GSK3196165)|DRUG: csDMARD(s)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Retrospective and Prospective Observational Study of MRI Changes in Bone and Visceral Lesions of Patients With Type 1 Gaucher Disease Treated With VPRIV® (Velaglucerase Alfa)
Status: COMPLETED
Conditions: Gaucher Disease, Type 1|MRI
Interventions: OTHER: MRI
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Determining Rates of Cardiovascular Complications Among Patients of a Managed Diabetes Care Program
Status: UNKNOWN
Conditions: Disease Management|Diabetes Complications|Diabetic Vascular Complications|Diabetic Neuropathy|Diabetic Nephropathy|Diabetic Retinopathy
Interventions: OTHER: ADEC Program
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Better Disease Control by Multidrug Regimen in Scabies
Status: COMPLETED
Conditions: Scabies
Interventions: DRUG: Permethrin Lotion 5%|DRUG: Permethrin Lotion 5% and Oral Ivermectin 200 mcg/kg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Raltegravir + Lopinavir/Ritonavir or Emtricitabine/Tenofovir for HIV Treatment Naive Subjects
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Raltegravir & Lopinavir/ritonavir|DRUG: Raltegravir and emtricitabine/tenofovir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antral Follicle Priming Prior to ICSI (Intracytoplasmic Sperm Injection) in Previously Diagnosed Low Responders
Status: COMPLETED
Conditions: Ovarian Diseases
Interventions: DRUG: Testosterone|DRUG: Estradiol|DRUG: CombEq
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Headache Inducing Effect of Levcromakalim in Migraine With Aura Patients
Status: COMPLETED
Conditions: Headache|Migraine|Aura
Interventions: DRUG: Levcromakalim|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Phase 1 Study of Multiple-Dose Pharmacokinetics of Cenicriviroc in Subjects With Mild and Moderate Hepatic Impairment
Status: COMPLETED
Conditions: Liver Insufficiency
Interventions: DRUG: Cenicriviroc in mild liver impaired|DRUG: Cenicriviroc in moderate liver impaired
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Prospective Study to Determine the Factors Influencing Infant Colic
Status: COMPLETED
Conditions: Infant Colic
Interventions: DIETARY_SUPPLEMENT: AB-Kolicare|DIETARY_SUPPLEMENT: Reuteri gotas
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Positron Emission Tomography (PET) Study of Brain Calcitonin Gene-Related Peptide (CGRP) Receptor Occupancy After Telcagepant Administration (MK-0974-067)
Status: COMPLETED
Conditions: Migraine
Interventions: DRUG: telcagepant|DRUG: [11C]MK-4232
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cabozantinib in Women With Metastatic Hormone-Receptor-Positive Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Cabozantinib|DRUG: Fulvestrant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Serial, Non-invasive Analysis of Exhaled Breath Condensate in Ventilated Trauma Patients
Status: TERMINATED
Conditions: Ventilator Associated Pneumonia (VAP)
Interventions: PROCEDURE: molecular analysis of exhaled breath condensate|PROCEDURE: molecular analysis of mini-bronchoalveolar lavage (BAL) aspirate|PROCEDURE: molecular analysis of bronchoalveolar lavage (BAL) aspirate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Prednisone Withdrawal Versus Prednisone Maintenance After Kidney Transplant
Status: TERMINATED
Conditions: Transplants and Implants
Interventions: DRUG: prednisone|DRUG: rabbit antithymocyte globulin|DRUG: Tacrolimus|DRUG: Prednisone|DRUG: Mycophenolate mofetil|DRUG: Mycophenolate mofetil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Evaluation of Quadratus Lumborum and Transverses Abdominis Plane Block for Postoperative Pain Relief in Lower Abdominal Surgeries
Status: UNKNOWN
Conditions: Pain Relief to the Patient Following Abdominal Surgeries
Interventions: PROCEDURE: ultrasound guided quadratus lumborum or Transversus Abdominis plane block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Multicenter Clinical Trial to Evaluate the Efficacy of a Preventive Strategy Against CMV Infection in Heart Transplant Patients, Based on the Specific T Cells Response
Status: UNKNOWN
Conditions: Heart Transplant Infection|CMV Infection
Interventions: DIAGNOSTIC_TEST: ELISPOT IFN-γ assay
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Chemotherapy With or Without Biological Therapy in Treating Patients With Metastatic Prostate Cancer That Has Not Responded to Hormone Therapy
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: BIOLOGICAL: recombinant interferon alfa|DRUG: estramustine phosphate sodium|DRUG: isotretinoin|DRUG: mitoxantrone hydrochloride|DRUG: paclitaxel|DRUG: vinorelbine ditartrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Cognitive Health Promotion Project in the Community
Status: COMPLETED
Conditions: Alteration of Cognitive Function|Dietary Modification
Interventions: BEHAVIORAL: Lifestyle Counseling Usual Care|BEHAVIORAL: Lifestyle Counseling Telephone, Bimonth|BEHAVIORAL: Lifestyle Counseling Telephone, Month|BEHAVIORAL: Lifestyle Counseling Visit, Bimonth|BEHAVIORAL: Lifestyle Counseling Visit, Reward
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Bioequivalence Study of Amlodipine / Losartan/ Hydrochlorothiazide of PHARMALINE, Lebanon Under Fastion Conditions
Status: COMPLETED
Conditions: Fasting
Interventions: DRUG: Amlodipin, losartan, HCTZ
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pain Medications Following Thyroidectomy and Parathyroidectomy
Status: COMPLETED
Conditions: Thyroid Disease|Parathyroid Diseases
Interventions: DRUG: Non-narcotic group regimen|DRUG: Narcotic group regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Exercise on Appetite, Gut Peptides and Butyrylcholinesterase Activity in Variants of the FTO Gene
Status: COMPLETED
Conditions: Appetitive Behavior
Interventions: OTHER: Control|OTHER: Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Direct Endovascular Treatment Versus Bridging Treatment In Basilar Artery Occlusive Stroke
Status: RECRUITING
Conditions: Acute Ischemic Stroke|Basilar Artery Occlusion|Thrombosis|Alteplase|Endovascular Treatment
Interventions: PROCEDURE: Endovascular treatment|DRUG: Intravenous thrombolysis (Alteplase)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mechanistic Effects of Health Coaching to Reduce Chronic Obstructive Pulmonary Disease (COPD) Hospitalizations
Status: COMPLETED
Conditions: COPD|Emphysema
Interventions: BEHAVIORAL: Health Coaching Calls|BEHAVIORAL: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of NanoChitosan Impregnated Calcium Hydroxide as an Intracanal Medication on Postoperative Pain Intensity and Bacterial Load Reduction
Status: NOT_YET_RECRUITING
Conditions: Intervention
Interventions: COMBINATION_PRODUCT: NanoChitosan impregnated Calcium Hydroxide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Laboratory Screening of Lorcaserin for Alcohol Use Disorder
Status: TERMINATED
Conditions: Alcohol Use Disorder|Tobacco Smoking
Interventions: DRUG: Lorcaserin Oral Tablet|DRUG: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Treatment With BIIL 284 BS on Exercise Endurance in Patients With Chronic Obstructive Pulmonary Disease
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Low dose of BIIL 284 BS tablets|DRUG: Medium dose of BIIL 284 BS tablets|DRUG: High dose of BIIL 284 BS tablets|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Induction of Drug Metabolism: In Vivo Comparison of Carbamazepine and Oxcarbazepine.
Status: COMPLETED
Conditions: Metabolic Clearance Rate
Interventions: DRUG: carbamazepine oxcarbazepine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Polyaxial Locking Plate Osteosynthesis in Proximal Tibia Fractures
Status: COMPLETED
Conditions: Tibia Plateau Fracture
Interventions: PROCEDURE: VA-LCP|PROCEDURE: NCB-PT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Mindfulness-Based Stress Reduction in Helping Participants With Metastatic Breast Cancer
Status: COMPLETED
Conditions: Stage IV Breast Cancer
Interventions: OTHER: Laboratory Biomarker Analysis|BEHAVIORAL: Meditation-Based Stress Reduction Program|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Observational Study of Botulinum Toxin Type A in Patients With Urinary Incontinence Associated With Overactive Bladder
Status: COMPLETED
Conditions: Urinary Bladder, Overactive|Urinary Bladder, Neurogenic
Interventions: BIOLOGICAL: botulinum toxin Type A
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: ALPINE: Maintenance Letrozole/Abemaciclib vs Pembrolizumab
Status: RECRUITING
Conditions: Endometrial Cancer|Recurrent Endometrial Cancer|TP53
Interventions: DRUG: Abemaciclib|DRUG: Letrozole|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT