pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Post-Endodontic Instrumentation Pain After in a Single Session Associated With Photobiomodulation
Status: NOT_YET_RECRUITING
Conditions: Pain, Postoperative|Endodontically Treated Teeth
Interventions: PROCEDURE: Endodontic Treatment|DEVICE: Low Level Laser Therapy|DEVICE: Simulation Low Level Laser therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Reframe the Pain: A Parent-Led Intervention to Alter Children's Memories for Pain
Status: COMPLETED
Conditions: Psychology|Pain|Stress|Behavior|Coping|Emotion, Expressed
Interventions: BEHAVIORAL: Pain Reframing Intervention|BEHAVIORAL: Attention Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Analgesia of Erector Spinae Plane Block Versus Quadratus Lumborum Block
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: OTHER: Erector spinae plane block|OTHER: Quadratus lumborum block|DRUG: Propofol|DRUG: Fentanyl NCS|DRUG: Atracurium Injectable Product|OTHER: Endotracheal intubation|DRUG: Anesthesia Maintenance|DRUG: Muscle Relaxation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Ten Patient Pilot Study to Evaluate Safety of the ZetaFuse™ Bone Graft Administered Using an Outpatient Local Intratumoral Injection Procedure to Treat Breast Cancer Bone Metastases in the Spine to Control Pain and Prevent Complications Such as Fracture
Status: RECRUITING
Conditions: Metastatic Breast Cancer in the Spine
Interventions: DEVICE: ZetaFuse™ Bone Graft
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Melatonin 3mg and 5mg Compared to Cognitive Behavioral Therapy for Insomnia (CBT-I) in the Treatment of Insomnia
Status: UNKNOWN
Conditions: Insomnia Disorder
Interventions: BEHAVIORAL: CBT-I plus placebo|DRUG: CBT-I plus Melatonin 3 mg|DRUG: CBT-I plus Melatonin 5 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy Assessment of Chinese Herbal Medicine Jiangtang Tiaozhi Recipe Treating Participants With Glucose and Lipid Metabolism Disturbances
Status: RECRUITING
Conditions: Type2 Diabetes|Dyslipidemias
Interventions: DRUG: Jiangtang Tiaozhi recipe|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Global Response Assessment by Advanced Imaging and Myeloma Lesion Biopsies During Induction Therapy of Multiple Myeloma With Carfilzomib Lenalidomide Dexamethasone
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: PROCEDURE: Guided Lesion Biopsies|PROCEDURE: Standard Lesion Biopsies
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Inhaled Glutathione (GSH) Versus Placebo in Cystic Fibrosis
Status: UNKNOWN
Conditions: Cystic Fibrosis
Interventions: DRUG: Inhaled Reduced Glutathione|DRUG: Physiological solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Venetoclax+Azacytidine+Modified BUCY Conditioning Regimen for Acute Lymphoblastic Leukemia Undergoing Allo-HSCT
Status: RECRUITING
Conditions: Allogeneic Hematopoietic Stem Cell Transplantation|Acute Lymphoblastic Leukemia
Interventions: DRUG: VEN+AZA+Modified BUCY
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Outcomes Study in Patients Receiving Aspirin With Mechanical Compression Devices Versus Aspirin Alone Following Knee and Hip Arthroplasty
Status: WITHDRAWN
Conditions: DVT - Deep Vein Thrombosis|PE - Pulmonary Thromboembolism
Interventions: DRUG: Aspirin|DEVICE: (Post- discharge) Mechanical Compression Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: SAbR Induced Innate Immunity in Urothelial Carcinoma, Melanoma, and Cervical Carcinoma
Status: COMPLETED
Conditions: Urothelial Carcinoma|Melanoma|Cervical Carcinoma in Situ
Interventions: RADIATION: SAbR Treatment of Lesions
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: An fMRI Study of Jianpi Yishen Huatan Granules for Cognitive Impairment After Acute Cerebral Infarction
Status: UNKNOWN
Conditions: Cognitive Impairment
Interventions: DRUG: Jianpi Yishen Huatan Granules|OTHER: the placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Effectiveness and Safety of Risperidone Versus Placebo as add-on Therapy to Mood Stabilizers, in the Treatment of Manic Episodes Associated With Bipolar Disorder.
Status: COMPLETED
Conditions: Bipolar Disorder|Manic Disorder
Interventions: DRUG: risperidone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: The Role of Intravenous (IV) Lidocaine in the Management of Chronic Neuropathic Pain of Peripheral Nerve Origin
Status: COMPLETED
Conditions: Neuropathic Pain
Interventions: DRUG: Lidocaine|DRUG: Diphenhydramine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Clinical Comparison of Vital Pulp Capping Restorative Protocols
Status: COMPLETED
Conditions: Deep Dental Caries
Interventions: PROCEDURE: Indirect Pulp capping-Resin-modified calcium silicate - TheraCal|PROCEDURE: Indirect Pulp capping-Calcium hydroxide - Dycal|PROCEDURE: Indirect Pulp capping-Resin-based dentin bonding agent|PROCEDURE: Direct Pulp capping-Resin-modified calcium silicate - TheraCal|PROCEDURE: Direct Pulp capping-Calcium hydroxide - Dycal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Efficacy of Tadalafil/Solifenacin VS Tamsulosin/Solifenacin Combination Therapy for BPH/OAB
Status: UNKNOWN
Conditions: Benign Prostatic Hyperplasia|Overactive Bladder
Interventions: DRUG: Tadalafil 5mg|DRUG: Tamsulosin Hcl 0.4 mg|DRUG: solifenacin 10 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: L-Carnitine L-Tartrate in Preventing Peripheral Neuropathy Caused By Chemotherapy in Women With Metastatic Breast Cancer
Status: TERMINATED
Conditions: Breast Cancer|Chemotherapeutic Agent Toxicity|Neurotoxicity
Interventions: DRUG: L-carnitine L-tartrate|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Daphnetin Capsules for Lower Limb Lymphoedema Following Gynaecological Surgery
Status: RECRUITING
Conditions: Lower Extremity Lymphedema
Interventions: DRUG: Daphnetin|DRUG: Aescuven
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aripiprazole Augmentation for Clozapine-Treated Patients With Refractory Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: aripiprazole|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial to Determine How Long Insulin and FDKP (the Molecule That Forms Technosphere Particles) Stays in the Lungs of Healthy Individuals After Inhalation of Technosphere® Insulin (TI) Powder Using Bronchoalveolar Lavage (BAL)
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: TI Inhalation Powder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SHP-141C in Plaque Type Psoriasis
Status: COMPLETED
Conditions: Plaque Type Psoriasis
Interventions: DRUG: SHP-141C|DRUG: Placebo to SHP-141C|DRUG: Betamethasone Valerate|DRUG: Calcipotriol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Pembrolizumab (MK-3475) Plus V940 in Participants With Bladder Cancer Post-Radical Resection (V940-005)
Status: RECRUITING
Conditions: Bladder Cancer
Interventions: BIOLOGICAL: Pembrolizumab|BIOLOGICAL: V940|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Early Post-operative Removal of Urethral Catheter in Patients Undergoing Colorectal Surgery With Epidural Analgesia
Status: COMPLETED
Conditions: Urinary Retention
Interventions: OTHER: Removal of urethral catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Type 1 Together: A Peer Mentorship Program to Increase Equitable Use of Continuous Glucose Monitoring Systems
Status: ENROLLING_BY_INVITATION
Conditions: Diabetes Mellitus, Type 1
Interventions: BEHAVIORAL: Standard of Care|BEHAVIORAL: Type 1 Together
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Rapamycin (Sirolimus) in the Treatment of Symptomatic Uterine Fibroids and Leiomyomatosis
Status: UNKNOWN
Conditions: Uterine Fibroids
Interventions: DRUG: rapamycin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Platelet Rich Fibrin Versus Platelet Rich Plasma for Microneedling Treatment of Facial Photoaging
Status: NOT_YET_RECRUITING
Conditions: Photoaging
Interventions: PROCEDURE: platelet-rich fibin|PROCEDURE: platelet-rich palsma
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Avatrombopag for HCC Patients With Thrombocytopenia Who Intend to Undergo TACE and/or HAIC
Status: RECRUITING
Conditions: Thrombocytopenia|Hepatocellular Carcinoma
Interventions: DRUG: Avatrombopag
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of GSK598809, a Selective D3 Antagonist, Added to CBT and NRT for Smoking Cessation and Relapse Prevention
Status: COMPLETED
Conditions: Nicotine Dependence
Interventions: DRUG: GSK598809|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Phase 2 Herniorrhaphy Study for Opioid Elimination
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: HTX-011|DEVICE: Luer lock applicator|DEVICE: Vial access device|DRUG: Ibuprofen|DRUG: Acetaminophen|DRUG: Ketorolac
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Endoscopic Pyloromyotomy for Refractory Gastroparesis
Status: COMPLETED
Conditions: Gastroparesis
Interventions: PROCEDURE: Gastric endoscopic peroral pyloromyotomy|PROCEDURE: Esophago-gastro-duodenoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Magnesium Sulfate Versus 5% Dextrose With Treatment Resistant Depression
Status: COMPLETED
Conditions: Depression
Interventions: DIETARY_SUPPLEMENT: Magnesium sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Single-Ascending Dose Study to Assess the Safety, Tolerability, and Pharmacokinetics of YJ001 in Healthy Volunteers
Status: COMPLETED
Conditions: Safety and Tolerability
Interventions: DRUG: YJ001 for Spray Use|DRUG: Placebo of YJ001 for Spray Use
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: EFFECT OF DIFFERENT NOREPINPHRINE APPLICATION METHODS IN CAESARIANES ON HYPOTENSION AFTER SPINAL ANESTHESIA
Status: UNKNOWN
Conditions: HYPOTENSION AFTER SPINAL ANESTHESIA,IN PREGNANCY
Interventions: DRUG: Norepinephrine|DRUG: Norepinephrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Leukocyte Dna mEthylation and micRoBIOME Diversity on Host Defense Mechanisms During Community-acquired Pneumonia (ELDER-BIOME)
Status: UNKNOWN
Conditions: Pneumonia
Interventions: OTHER: rectal swab|OTHER: nasopharyngeal swab|OTHER: blood draw
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Ten-Year Outcomes of Randomized Comparison of Coronary Artery Bypass Surgery and Everolimus-Eluting Stent Implantation in the Treatment of Patients With Multivessel Coronary Artery Disease
Status: COMPLETED
Conditions: Multivessel Coronary Artery Disease
Interventions: PROCEDURE: coronary stent implantation|PROCEDURE: bypass grafting
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Nivolumab and Relatlimab in Patients With Microsatellite Stable (MSS) Advanced Colorectal Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Microsatellite Stable (MSS) Colorectal Adenocarcinomas|Colorectal Adenocarcinoma
Interventions: DRUG: Nivolumab|DRUG: Relatlimab|DRUG: Nivolumab|DRUG: Relatlimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Promoting the Development of Autonomous Health Behaviors in Children and Adolescents Through Motivational Interviewing
Status: NOT_YET_RECRUITING
Conditions: Pediatric Obesity
Interventions: BEHAVIORAL: Motivational Interviewing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Evaluating the Safety and Drug Levels of an Antibody Against HIV in Healthy, HIV-Uninfected Adults
Status: COMPLETED
Conditions: HIV Infections
Interventions: BIOLOGICAL: VRC01|BIOLOGICAL: SC placebo for VRC01|BIOLOGICAL: IV placebo for VRC01
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Melphalan, Thalidomide, and Dexamethasone in Treating Patients With Newly Diagnosed, Previously Untreated Primary Systemic Amyloidosis
Status: COMPLETED
Conditions: Multiple Myeloma and Plasma Cell Neoplasm
Interventions: BIOLOGICAL: filgrastim|DRUG: dexamethasone|DRUG: melphalan|DRUG: thalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Imagery Therapy vs Progressive Muscle Relaxation Therapy on Patients With Functional Abdominal Bloating
Status: COMPLETED
Conditions: Functional Gastrointestinal Disorders
Interventions: BEHAVIORAL: Guided Imagery|BEHAVIORAL: Progressive Muscle Relaxation|OTHER: Educational Audiobook
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Individualized iTBS on Upper Limb Function After Stroke
Status: NOT_YET_RECRUITING
Conditions: Upper Extremity Paresis|Stroke
Interventions: DEVICE: individualized intermittent theta burst sitmulation (iTBS)|DEVICE: standard iTBS|DEVICE: sham stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Midostaurin in Patients With Aggressive Systemic Mastocytosis or Mast Cell Leukemia
Status: COMPLETED
Conditions: Leukemia
Interventions: DRUG: Midostaurin (PKC412)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preemptive Co-infiltration of Dexamethasone Palmitate With Ropivacaine for Postoperative Pain in Major Spinal Surgery
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: DRUG: Dexamethasone palmitate emulsion(DXP) plus ropivacaine|DRUG: Ropivacaine alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: An Investigation Into the Efficacy of Provodine Topical Cream as Compared to 10% Benzoyl Peroxide Wash for the Treatment of Hidradenitis Suppurativa.
Status: COMPLETED
Conditions: Hidradenitis Suppurativa
Interventions: DRUG: 10% Benzoyl Peroxide Topical Body Wash|DRUG: Provodine Topical Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: MIndfulness-based Physical Exercise Program (MIPE Program) on Sarcopenia
Status: RECRUITING
Conditions: Sarcopenia
Interventions: OTHER: mindfulness-based phsycial exercise intervention|OTHER: health education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Laughter Yoga on the Anxiety and Stress Levels of Women in the Postpartum Period
Status: COMPLETED
Conditions: Laughter Yoga
Interventions: BEHAVIORAL: Experimental: Laughter yoga session parts-1|BEHAVIORAL: Experimental: Laughter yoga session parts-2|BEHAVIORAL: Experimental: Laughter yoga session parts-3|BEHAVIORAL: Experimental: Laughter yoga session parts-4
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Randomized Controlled Clinical Study of Drug Therapy Combined With Thoracic Radiotherapy for Non-oligometastatic NSCLC
Status: UNKNOWN
Conditions: Stage IV Non-small Cell Lung Cancer
Interventions: RADIATION: Thoracic Three-dimensional Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Histopathological Response to FOLFOXIRI + Bevacizumab in Peritoneal Metastasis From Colorectal Cancer
Status: UNKNOWN
Conditions: Colorectal Cancer|Peritoneal Metastasis
Interventions: PROCEDURE: Upfront staging laparoscopy + peritoneal biopsy|DRUG: Neoadjuvant chemotherapy with FOLFOXIRI + bevacizumab|PROCEDURE: Surgical re-exploration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Over-The-Counter Use of Low Level Laser Light Therapy for Body Contouring of the Waist, Hips and Thighs
Status: COMPLETED
Conditions: Circumference Reduction
Interventions: DEVICE: Lay End Users|DEVICE: Treatment Subject Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Weight Management Plus Megestrol Acetate in Early-stage Endometrioid Carcinoma
Status: RECRUITING
Conditions: Endometrial Carcinoma|Obese|Overweight|Fertility Issues
Interventions: BEHAVIORAL: Intensive Lifestyle Intervention (ILI)|DRUG: Megestrol Acetate 160 MG Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: QUality of Control and slEep in Children With diabeteS, Using New Technology
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: DEVICE: CGM augmented pump with PLGS ,|DEVICE: Insulin pump with CGM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open-Label, Multicenter Extension Study for Patients Completing Treatment Phase of a Rigel-Sponsored R935788 Studies
Status: TERMINATED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Fostamatinib Disodium (R935788)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study on Ketoprofen Lysine Salt (KLS) + Gabapentin (GABA) vs KLS to Investigate Their Pharmacodynamic in Healthy Males
Status: COMPLETED
Conditions: No Condition
Interventions: DRUG: Ketoprofen Lysine Salt combined with Gabapentin|DRUG: Ketoprofen Lysine Salt|DRUG: Gabapentin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Training Intensity on Physical Fitness and Body Composition in Cystic Fibrosis
Status: ACTIVE_NOT_RECRUITING
Conditions: Cystic Fibrosis
Interventions: OTHER: High Intensity Interval Training (HIIT)|OTHER: Moderate Continuous Intensity Training (MICT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Alfuzosin Hydrochloride to Relieve Ureteral Stent Discomfort
Status: COMPLETED
Conditions: Ureteral Stent Discomfort
Interventions: DRUG: Alfuzosin Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose:
Clinical trial: IncobotulinumtoxinA (Xeomin) Versus Placebo in the Treatment of Blepharospasm
Status: COMPLETED
Conditions: Blepharospasm
Interventions: DRUG: incobotulinumtoxinA (Xeomin)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Investigation of the AcrySof IQ Vivity Extended Vision Intraocular Lens (IOL)
Status: COMPLETED
Conditions: Aphakia
Interventions: DEVICE: VIVITY|DEVICE: SYMFONY|DEVICE: AT LARA|PROCEDURE: Cataract surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of CF101 to Treat Patients With Psoriasis
Status: COMPLETED
Conditions: Plaque Psoriasis
Interventions: DRUG: CF101|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Different Anti-platelet Strategies on the Long-term Outcome After Sirolimus Drug-eluting Stent Implantation
Status: UNKNOWN
Conditions: Coronary Artery Disease
Interventions: DRUG: clopidogrel|DRUG: placebo|DRUG: clopidogrel and placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: COVID-19 Brief Advice and Chat-based Support for Smoking Cessation Via "Quit to Win" Contest 2020
Status: COMPLETED
Conditions: Smoking Cessation
Interventions: BEHAVIORAL: Chat-based support|BEHAVIORAL: AWARD plus COVID-specific advice|BEHAVIORAL: AWARD advice|BEHAVIORAL: COVID-19 related health warning leaflet|BEHAVIORAL: Health warning leaflet|BEHAVIORAL: SMS-based support|BEHAVIORAL: Referral card|BEHAVIORAL: COSH Self-help smoking cessation booklet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Gene Therapy in Treating Patients With Advanced Bladder Cancer
Status: COMPLETED
Conditions: Recurrent Bladder Cancer|Stage I Bladder Cancer|Stage II Bladder Cancer|Stage III Bladder Cancer|Stage IV Bladder Cancer|Transitional Cell Carcinoma of the Bladder
Interventions: BIOLOGICAL: Ad5CMV-p53 gene
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intraoperative Imaging of Pulmonary Nodules by SGM-101
Status: COMPLETED
Conditions: Lung Cancer|Lung Nodule|Non Small Cell Lung Cancer
Interventions: DRUG: SGM-101|DEVICE: Near infrared camera imaging system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Efficacy Testing of Melon Oil Olive Pressed Candy Products
Status: COMPLETED
Conditions: Skin Condition
Interventions: DIETARY_SUPPLEMENT: Placebo candy|DIETARY_SUPPLEMENT: melon and oil olive pressed candy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Exercise Training Sequence for Subacromial Impingement Syndrome
Status: COMPLETED
Conditions: Subacromial Impingement Syndrome
Interventions: OTHER: Rotator Cuff Training|OTHER: Scapular Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Neratinib In Combination With Chemotherapy/Trastuzumab/Pembrolizumab In HER2 Gastroesophageal Cancer
Status: RECRUITING
Conditions: GastroEsophageal Cancer|Gastric Cancer
Interventions: DRUG: Neratinib|DRUG: Trastuzumab|DRUG: Oxaliplatin|DRUG: 5-Fluorouracil + leucovorin|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating the Effects of GLPG3970 Given as Oral Treatment for 12 Weeks in Adults With Systemic Lupus Erythematosus
Status: TERMINATED
Conditions: Systemic Lupus Erythematosus
Interventions: DRUG: GLPG3970 film-coated tablet|DRUG: Placebo film-coated tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Meplazumab in Patients With Coronary Artery Disease
Status: RECRUITING
Conditions: Coronary Artery Disease
Interventions: DRUG: Mepolizumab low dose group|DRUG: Mepolizumab middle dose group|DRUG: Mepolizumab high dose group|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Accuracy for Predicting Deep Submucosal Invasion
Status: COMPLETED
Conditions: Colorectal Cancer|Colorectal Polyp
Interventions: DIAGNOSTIC_TEST: White light endoscopy (WLE)|DIAGNOSTIC_TEST: NBI/BLI +/- chromoendoscopy (NBIBLI +/- CE)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Controlled Trial of Mifepristone in Gulf War Veterans With Chronic Multisymptom Illness
Status: COMPLETED
Conditions: Chronic Multisymptom Illness in Gulf War Veterans
Interventions: DRUG: mifepristone|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Chemotherapy Followed by Radiation Therapy and Gemcitabine/Sorafenib/Vorinostat in Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Adenocarcinoma|Stage IA Pancreatic Cancer|Stage IB Pancreatic Cancer|Stage IIA Pancreatic Cancer|Stage IIB Pancreatic Cancer|Stage III Pancreatic Cancer|Recurrent Pancreatic Carcinoma
Interventions: DRUG: Gemcitabine|DRUG: Sorafenib|DRUG: Vorinostat|RADIATION: 3-Dimensional Conformal Radiation Therapy|RADIATION: Intensity-Modulated Radiation Therapy|OTHER: RosetteSep|OTHER: DEPfff
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Attention Bias Modification Treatment for Warzone-Related Posttraumatic Stress Disorder (PTSD)
Status: COMPLETED
Conditions: Posttraumatic Stress Disorder
Interventions: BEHAVIORAL: Attention Bias Modification Training Protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing the Efficacy, Safety, and Tolerability of Combination Antivirals (Amantadine, Ribavirin, Oseltamivir) Versus Oseltamivir for the Treatment of Influenza in Adults at Risk for Complications
Status: COMPLETED
Conditions: Influenza
Interventions: DRUG: Amantadine, Ribavirin, Oseltamivir|DRUG: Oseltamivir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Aneurysmorrhaphy of Vascular Access for Haemodialysis
Status: COMPLETED
Conditions: Patients With an Aneurysm of Native Vascular Access Indicated for Surgical Treatment
Interventions: PROCEDURE: Aneurysmorrhaphy with or without external porous prosthesis (Provena©, BBraun)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sorafenib With or Without Gemcitabine and Oxaliplatin in Treating Patients With Locally Advanced, Unresectable, or Metastatic Liver Cancer
Status: COMPLETED
Conditions: Liver Cancer
Interventions: DRUG: gemcitabine hydrochloride|DRUG: oxaliplatin|DRUG: sorafenib tosylate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: Topiramate 25 mg Tablets Under Fed Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Topiramate 2 x 25 mg tablet|DRUG: Topamax® Tablet 2 x 25 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: A Study to Assess the Efficacy of Inhaled Corticosteroid (ICS) Therapy in Moderate-Severe Bronchial Asthma
Status: COMPLETED
Conditions: Bronchial Asthma
Interventions: DRUG: inhaled corticosteroid therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Immunogenicity of GSK Biologicals' Candidate Vaccines RTS,S/AS02D (0.5 mL Dose) and RTS,S/AS02A (0.25 mL Dose) Administered IM According to a 0, 1, 2 Month Vaccination Schedule in Children Aged 3 to 5 Years Living in a Malaria-endemic Region of Mozambique.
Status: COMPLETED
Conditions: Malaria
Interventions: BIOLOGICAL: RTS,S/AS02D and RTS,S/AS02A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: |Primary Purpose: OTHER
Clinical trial: Safety and Efficacy of Long-term Somatropin Treatment in Children
Status: COMPLETED
Conditions: Growth Hormone Disorder|Growth Hormone Deficiency in Children|Foetal Growth Problem|Small for Gestational Age|Genetic Disorder|Turner Syndrome|Growth Disorder|Idiopathic Short Stature
Interventions: DRUG: somatropin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Intrapulmonary Recombinant Human Activated Protein C (APC) on Coagulation and Inflammation After Lipopolysaccharide (LPS)
Status: COMPLETED
Conditions: Pneumonia|Lipopolysaccharides
Interventions: DRUG: Drotrecogin alpha|DRUG: Saline (NaCl 0.9%)|DRUG: Endotoxin|PROCEDURE: Bronchoscopy|PROCEDURE: Blood sampling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: Evaluation of the GORE® VIABAHN® BALLOON EXPANDABLE ENDOPROSTHESIS (VIABAHN BX)
Status: COMPLETED
Conditions: Common Iliac Artery Occlusive Disease|External Iliac Artery Occlusive Disease|Peripheral Arterial Disease
Interventions: DEVICE: Stenting of common and/or external iliacs
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ambulation for Latency During Expectant Management of PPROM
Status: COMPLETED
Conditions: Preterm Premature Rupture of the Membranes|Pregnancy Complications|Pregnancy, High Risk
Interventions: BEHAVIORAL: Ambulation Group|BEHAVIORAL: Routine Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study to Assess the Safety, Tolerability, and Immunogenicity of RSVpreF in Adults at High Risk of Severe RSV Disease
Status: COMPLETED
Conditions: RESPIRATORY SYNCYTIAL VIRUS (RSV)
Interventions: BIOLOGICAL: RSVpreF|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Maximal Use Study to Determine the Pharmacokinetics of L-arginine After Exaggerated Oral Use of COL101
Status: COMPLETED
Conditions: Caries,Dental
Interventions: DRUG: L Arginine|DRUG: Sodium Fluoride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Study of Fisogatinib (BLU-554) in Patients With Hepatocellular Carcinoma
Status: COMPLETED
Conditions: Hepatocellular Carcinoma (HCC)
Interventions: DRUG: Fisogatinib (BLU-554)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Haloperidol, Droperidol, Ondansetron in Cannabis Hyperemesis
Status: TERMINATED
Conditions: Cyclic Vomiting Syndrome
Interventions: DRUG: Droperidol|DRUG: Haloperidol|DRUG: Ondansetron 8mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: CHABLIS7.5: A Study of the Efficacy and Safety of Subcutaneous Blisibimod in Subjects With Systemic Lupus Erythematosus With or Without Nephritis
Status: TERMINATED
Conditions: Systemic Lupus Erythematosus
Interventions: DRUG: Blisibimod|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Test How BI 764532 is Taken up by Tumours in People With Small-cell Lung Cancer or Neuroendocrine Cancer
Status: RECRUITING
Conditions: Small Cell Lung Carcinoma (SCLC)|Neuroendocrine Neoplasms
Interventions: DRUG: BI 764532|DRUG: [89Zr]Zr-BI 764532
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MK0974 (Telcagepant) for Migraine Prophylaxis in Patients With Episodic Migraine (0974-049)
Status: TERMINATED
Conditions: Migraine
Interventions: DRUG: Telcagepant 140 mg|DRUG: Telcagepant 280 mg|DRUG: 140 mg telcagepant placebo|DRUG: 280 mg telcagepant placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility Study of Anatomical Modeling for Image Guided Thoracic Surgery
Status: ACTIVE_NOT_RECRUITING
Conditions: Lung Neoplasm
Interventions: PROCEDURE: Computed Tomography|PROCEDURE: Therapeutic Conventional Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Analgesic Effect of Cathodal tDCS Over Right DLPFC in Subjects With Muscular TMD: a Double Blind Crossover RCT
Status: COMPLETED
Conditions: Craniomandibular Disorders
Interventions: DEVICE: tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Advancing mHealth-supported Adoption and Sustainment of an Evidence-based Mental Health Intervention in Sierra Leone
Status: RECRUITING
Conditions: Mental Health
Interventions: BEHAVIORAL: Youth Readiness Intervention (YRI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Evaluation of Pneumococcal Vaccine Formulations in Elderly
Status: COMPLETED
Conditions: Infections, Streptococcal
Interventions: BIOLOGICAL: Pneumococcal vaccine GSK2189241A|BIOLOGICAL: Pneumo 23™
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Fenretinide and Rituximab in Treating Patients With B-Cell Non-Hodgkin Lymphoma
Status: TERMINATED
Conditions: Adult Nodular Lymphocyte Predominant Hodgkin Lymphoma|B-cell Chronic Lymphocytic Leukemia|Contiguous Stage II Adult Burkitt Lymphoma|Contiguous Stage II Adult Diffuse Large Cell Lymphoma|Contiguous Stage II Adult Lymphoblastic Lymphoma|Contiguous Stage II Grade 1 Follicular Lymphoma|Contiguous Stage II Grade 2 Follicular Lymphoma|Contiguous Stage II Mantle Cell Lymphoma|Stage II Marginal Zone Lymphoma|Stage II Small Lymphocytic Lymphoma|Extranodal Marginal Zone B-cell Lymphoma|Nodal Marginal Zone B-cell Lymphoma|Noncontiguous Stage II Adult Burkitt Lymphoma|Noncontiguous Stage II Adult Diffuse Large Cell Lymphoma|Noncontiguous Stage II Adult Lymphoblastic Lymphoma|Noncontiguous Stage II Grade 1 Follicular Lymphoma|Noncontiguous Stage II Grade 2 Follicular Lymphoma|Noncontiguous Stage II Mantle Cell Lymphoma|Recurrent Adult Burkitt Lymphoma|Recurrent Adult Diffuse Large Cell Lymphoma|Recurrent Adult Hodgkin Lymphoma|Recurrent Adult Lymphoblastic Lymphoma|Recurrent Grade 1 Follicular Lymphoma|Recurrent Grade 2 Follicular Lymphoma|Recurrent Mantle Cell Lymphoma|Recurrent Marginal Zone Lymphoma|Recurrent Small Lymphocytic Lymphoma|Refractory Chronic Lymphocytic Leukemia|Splenic Marginal Zone Lymphoma|Stage I Adult Burkitt Lymphoma|Stage I Adult Diffuse Large Cell Lymphoma|Stage I Adult Hodgkin Lymphoma|Stage I Adult Lymphoblastic Lymphoma|Stage I Chronic Lymphocytic Leukemia|Stage I Grade 1 Follicular Lymphoma|Stage I Grade 2 Follicular Lymphoma|Stage I Small Lymphocytic Lymphoma|Stage II Adult Hodgkin Lymphoma|Stage II Chronic Lymphocytic Leukemia|Stage III Adult Burkitt Lymphoma|Stage III Adult Diffuse Large Cell Lymphoma|Stage III Adult Hodgkin Lymphoma|Stage III Adult Lymphoblastic Lymphoma|Stage III Chronic Lymphocytic Leukemia|Stage III Grade 1 Follicular Lymphoma|Stage III Grade 2 Follicular Lymphoma|Stage III Mantle Cell Lymphoma|Stage III Marginal Zone Lymphoma|Stage III Small Lymphocytic Lymphoma|Stage IV Adult Burkitt Lymphoma|Stage IV Adult Diffuse Large Cell Lymphoma|Stage IV Adult Hodgkin Lymphoma|Stage IV Adult Lymphoblastic Lymphoma|Stage IV Chronic Lymphocytic Leukemia|Stage IV Grade 1 Follicular Lymphoma|Stage IV Grade 2 Follicular Lymphoma|Stage IV Mantle Cell Lymphoma|Stage IV Marginal Zone Lymphoma|Stage IV Small Lymphocytic Lymphoma|Waldenström Macroglobulinemia
Interventions: DRUG: fenretinide|DRUG: rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Action Observation Therapy on Upper Extremity Function in Children With Obstetric Brachial Plexus Injury
Status: COMPLETED
Conditions: Brachial Plexus Palsy|Obstetric; Injury
Interventions: BEHAVIORAL: Action Observation Therapy|BEHAVIORAL: Photo Observation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Sorafenib in Combination With Cytarabine and Clofarabine in Patients With Refractory or Relapsed Hematologic Malignancies
Status: COMPLETED
Conditions: Acute Myeloid Leukemia|Infantile Leukemia (Both AML and ALL)|Myelodysplastic Syndrome|Myelodysplastic/Myeloproliferative Neoplasms|Biphenotypic Leukemia
Interventions: DRUG: Sorafenib|DRUG: Cytarabine|DRUG: Clofarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Keratoconus With PALK Versus PK
Status: COMPLETED
Conditions: Keratoconus
Interventions: PROCEDURE: Penetrating keratoplasty|PROCEDURE: Pachymetry and Excimer laser assisted lamellar keratoplasty|DRUG: Treatment posterior to surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of AK119 and AK112 With or Without Chemotherapy for NSCLC Patients
Status: RECRUITING
Conditions: NSCLC
Interventions: DRUG: AK119|DRUG: AK112|DRUG: Pemetrexed|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Proactive Treatments in Patients With Wet Age-related Macular Degeneration (wAMD) Which Have Never Undergone Treatment of This Particular Disease
Status: COMPLETED
Conditions: Wet Age-related Macular Degeneration
Interventions: DRUG: Aflibercept (Eylea, BAY86-5321)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: RIC With Thiotepa Combined With Bu/Flu/Ara-C in Allo-HSCT for Relapsed or Refractory PTCL.
Status: RECRUITING
Conditions: Peripheral T Cell Lymphoma
Interventions: DRUG: Thiotepa
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Chimeric Fibril-Reactive Monoclonal Antibody 11-1F4 in Patients With AL Amyloidosis
Status: COMPLETED
Conditions: Amyloidosis
Interventions: DRUG: Chimeric Fibril-Reactive Monoclonal Anti-body 11-1F4
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Effectiveness and Safety Study of Decitabine in Patients With Myelodysplastic Syndrome
Status: COMPLETED
Conditions: Myelodysplastic Syndrome
Interventions: DRUG: Decitabine at 15 mg/m2|DRUG: Decitabine at 20 mg/m2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination of Medium Cut-off Dialyzer Membrane and Diet Modification to Alleviate Residual Uremic Syndrome of Dialysis Patients
Status: UNKNOWN
Conditions: End Stage Renal Disease|Haemodialysis|Diet, Healthy
Interventions: DEVICE: medium cut-off (MCO) dialysis membrane|DIETARY_SUPPLEMENT: Dietary fiber mixture (Plantago Psyllium and Inulin)|DIETARY_SUPPLEMENT: Sodium propionate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Xian Risperdal Tablets Compared With Gurabo Risperdal Tablets Under Fasting and Fed Conditions in Chinese Healthy Participants
Status: WITHDRAWN
Conditions: Healthy
Interventions: DRUG: Risperidone: Xian Risperdal (test)|DRUG: Risperidone: Gurabo Risperdal (reference)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Physical Activity in Transfusion Dependent Patients With Myelodysplastic Syndrome
Status: WITHDRAWN
Conditions: Myelodysplastic Syndromes
Interventions: OTHER: Medical Device Usage and Evaluation|PROCEDURE: Biospecimen Collection|OTHER: Questionnaire Administration|OTHER: Quality-of-Life Assessment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Levofloxacin Concomitant Versus Levofloxacin Sequential
Status: NOT_YET_RECRUITING
Conditions: Helicobacter Pylori Infection
Interventions: DRUG: sequential|DRUG: Levofloxacin 500Mg Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Influence of Intraoral Photobiomodulation in Individuals With Temporomandibular Joint Dysfunction
Status: COMPLETED
Conditions: Temporomandibular Disorders
Interventions: OTHER: Photobiomodulation|OTHER: Photobiomodulation placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SOFEED: Six Food vs. One Food Eosinophilic Esophagitis Diet Study
Status: COMPLETED
Conditions: Eosinophilic Gastrointestinal Disorders (EGIDs)|Eosinophilic Esophagitis (EoE)
Interventions: OTHER: 1 Food Elimination Diet Therapy|OTHER: 6 Food Elimination Diet Therapy|OTHER: 6 Food Elimination Diet (after 1FED failure)|DRUG: Fluticasone Propionate, 880 mcg twice daily (after 6FED failure)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preventive Treatment Of Latent Tuberculosis Infection In People With Diabetes Mellitus
Status: RECRUITING
Conditions: Diabetes Mellitus|Tuberculosis
Interventions: DRUG: Isoniazid and Rifapentine (INH-RPT)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Efficacy of Different Bupivacaine Concentrations in Pediatric Patients Undergoing Transversus Abdominis Plane Block
Status: COMPLETED
Conditions: Transversus Abdominis Plane Block
Interventions: DRUG: 1 mg.kg-1 bupivacaine 0.25%|DRUG: 1 mg.kg-1 bupivacaine 0.125%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison Of The Effect Of Propolis And Gluma Desensitizer On The Management Of Dentin Hypersensitivity
Status: COMPLETED
Conditions: Dentin Hypersensitivity
Interventions: DRUG: Propolis|DRUG: Gluma Desensitizer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT