pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Safety and Efficacy of Intranasal Ketamine for the Treatment of Postoperative Dental Pain
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: DRUG: intranasal ketamine|DRUG: intranasal ketamine|DRUG: intranasal ketamine|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Misoprostol in the Prevention of Postpartum Haemorrhage
Status: UNKNOWN
Conditions: Postpartum Hemorrhage
Interventions: DRUG: 200 micrograms of misoprostol|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Testing A New Combination of Anti-cancer Immune Therapies, Atezolizumab and CDX-1127 (Varlilumab) With or Without the Addition of a Third Anti-cancer Drug, Cobimetinib, for Advanced-Stage Biliary Tract Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Distal Bile Duct Adenocarcinoma|Metastatic Gallbladder Carcinoma|Metastatic Intrahepatic Cholangiocarcinoma|Recurrent Distal Bile Duct Adenocarcinoma|Recurrent Gallbladder Carcinoma|Recurrent Intrahepatic Cholangiocarcinoma|Stage IV Distal Bile Duct Cancer AJCC v8|Stage IV Gallbladder Cancer AJCC v8|Stage IV Intrahepatic Cholangiocarcinoma AJCC v8|Unresectable Liver Carcinoma
Interventions: BIOLOGICAL: Atezolizumab|PROCEDURE: Biopsy|PROCEDURE: Biospecimen Collection|DRUG: Cobimetinib|PROCEDURE: Computed Tomography|PROCEDURE: Magnetic Resonance Imaging|DRUG: Varlilumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability Study of MBX-2044 in Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: MBX-2044|DRUG: MBX-2044|DRUG: MBX-2044|DRUG: MBX-2044|DRUG: MBX-2044|DRUG: MBX-2044|DRUG: Placebo for MBX-2044
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Value of I-Scan and Confocal Laser Endomicroscopy for the Assessment of Chronic Inflammatory Bowel Disease
Status: TERMINATED
Conditions: Inflammatory Bowel Disease|Crohn's Disease|Ulcerative Colitis|Dysplasia
Interventions: OTHER: Confocal laser endomicroscopy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Cannabidiol as a Different Type of an Antipsychotic: Drug Delivery and Interaction Study
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Cannabidiol CR|DRUG: Cannabidiol|DRUG: Amisulpride|DRUG: Olanzapine|DRUG: Quetiapine|DRUG: Risperidone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hormone Therapy, Radiation Therapy, and Steroid 17alpha-monooxygenase TAK-700 in Treating Patients With High-Risk Prostate Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Cancer
Interventions: DRUG: GnRH agonist|DRUG: Anti-androgen|DRUG: TAK-700|RADIATION: Radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Re-Purposing the Ordering of Routine Laboratory Tests in Hospitals in British Columbia
Status: NOT_YET_RECRUITING
Conditions: Hospital Acquired Condition
Interventions: BEHAVIORAL: Laboratory test overuse (LTO) Bundle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Endoscopic Ultrasound and Endoscopic Retrograde Cholangiopancreatography for Malignant Distal Biliary Obstruction
Status: COMPLETED
Conditions: Pancreatic Cancer|Pancreatic Neoplasms|Pancreatic Adenocarcinoma
Interventions: PROCEDURE: EUS-BD|PROCEDURE: ERCP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Cigarette and E-cigarette Nicotine Content in an Electronic Tobacco Marketplace (ETM)
Status: COMPLETED
Conditions: Tobacco Use
Interventions: OTHER: Normal Nicotine Content Vape with all flavor e-liquids|OTHER: Normal nicotine content vape with tobacco e-liquids|OTHER: Low nicotine content vape with all flavor e-liquids|OTHER: Low nicotine content vape with tobacco e-liquids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Behavioral Insomnia Treatment in Mild Traumatic Brain Injury
Status: NOT_YET_RECRUITING
Conditions: Insomnia|Mild Traumatic Brain Injury
Interventions: BEHAVIORAL: Cognitive Behavioral Therapy for Insomnia|BEHAVIORAL: Brief Behavioral Therapy for Insomnia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chronic Kidney Disease (CKD) Guideline Adherence - A Quality Improvement Study
Status: COMPLETED
Conditions: Chronic Renal Insufficiency
Interventions: BEHAVIORAL: Education only|BEHAVIORAL: Multifactorial intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Effect of Medical Clown on the Pain and Anxiety Perception During LRH Analog Treatment or GH Provocation Test
Status: COMPLETED
Conditions: Precocious Puberty|Growth Hormone Tests
Interventions: BEHAVIORAL: Presence of medical clown during endocrine test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Bevacizumab and Oxaliplatin Combined With Irinotecan or Leucovorin and Fluorouracil in Treating Patients With Metastatic or Recurrent Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: BIOLOGICAL: bevacizumab|DRUG: fluorouracil|DRUG: irinotecan hydrochloride|DRUG: leucovorin calcium|DRUG: Oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating Short-term Effects of Computerized Brain Fitness Exercises in Adult Cochlear Implant and/or Hearing Aid Users
Status: TERMINATED
Conditions: Deafness|Speech Intelligibility
Interventions: OTHER: Cognitive fitness training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Dermal Autograft to AlloDerm in Breast Reconstruction
Status: COMPLETED
Conditions: Mastectomy Related Lymphedema|Breast Reconstruction|Breast Cancer
Interventions: PROCEDURE: Dermal Autograft|PROCEDURE: AlloDerm
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Early Effect of Cingal® Compared to Monovisc® in Patients With Osteoarthritis of the Knee
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: DEVICE: Cingal® (Hyaluronic Acid plus Triamcinolone Hexacetonide)|DEVICE: Monovisc® (Sodium hyaluronate)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Frequent Activity Snacks Breaks
Status: COMPLETED
Conditions: Obesity|Insulin Resistance|Sedentary Lifestyle
Interventions: BEHAVIORAL: Normal lifestyle|BEHAVIORAL: Exercise|PROCEDURE: muscle and fat biopsy|DEVICE: Continuous glucose monitoring|DEVICE: Activity monitoring (ActivePal)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Safety of Ozonised Oil (HOO) in COVID-19 Patients
Status: WITHDRAWN
Conditions: SARS-CoV Infection
Interventions: DIETARY_SUPPLEMENT: Ozonized oil (HOO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Factors Predicting Outcome in Group Treatment of Alcohol Use Disorders (AUDs)
Status: ACTIVE_NOT_RECRUITING
Conditions: Alcohol Use Disorder (AUD)|Alcohol Abuse|Drug Abuse|Psychiatric Disorder|Personality Disorders|Cognitive Deficit|Cognitive Impairment|Substance Use Disorders
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phase II Part 2 Expansion of Oral Rigosertib in Combination With Azacitidine
Status: COMPLETED
Conditions: Myelodysplastic Syndrome|Acute Myeloid Leukemia|Chronic Myelomonocytic Leukemia
Interventions: DRUG: oral rigosertib|DRUG: Azacitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Combined Utility of Angio-CT and MRI in Managing Chronic Musculoskeletal Pain: a Prospective Study to Evaluate the Efficacy of Transarterial Microembolization
Status: RECRUITING
Conditions: Chronic Musculoskeletal Disease|Transarterial Embolization|Magnetic Resonance Imaging|Angiography|Computed Tomography
Interventions: PROCEDURE: Transarterial microembolization (TAME)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Innovative Tools to Expand HIV Self-Testing
Status: COMPLETED
Conditions: HIV/AIDS|Sexually Transmitted Diseases
Interventions: COMBINATION_PRODUCT: SMART Pack|COMBINATION_PRODUCT: Luv Box|COMBINATION_PRODUCT: Bili Vibes|COMBINATION_PRODUCT: BeterDoc|COMBINATION_PRODUCT: IUNGO
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Investigation How CG5503 is Taken up and Excreted From the Body After 2 Minutes Intravenous Infusion With and Without Oral Co-administration of Charcoal
Status: COMPLETED
Conditions: Pharmacokinetic
Interventions: DRUG: 4 ml CG5503|DRUG: 5 g charcoal powder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Zilebesiran as Add-on Therapy in Patients With High Cardiovascular Risk and Hypertension Not Adequately Controlled by Standard of Care Antihypertensive Medications (KARDIA-3)
Status: RECRUITING
Conditions: High Cardiovascular Risk|Hypertension
Interventions: DRUG: Zilebesiran|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use Of Gigstride Device In Patients With Lower Extremity Deficit
Status: NOT_YET_RECRUITING
Conditions: Ambulation Difficulty|Lower Extremity Problem
Interventions: DEVICE: Gigstride Ambulatory Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: A Multiple Ascending Dose Study of HTD1801 in Adults With Hypercholesterolemia
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DRUG: HTD1801 Tablets, 500 mg|DRUG: HTD1801 Tablets, 1000 mg|DRUG: HTD1801 Tablets, 2000 mg|DRUG: Placebo to match 500 mg HTD1801|DRUG: Placebo to match 1000 mg HTD1801|DRUG: Placebo to match 2000 mg HTD1801
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Emergency Department-To-Home Intervention to Improve Quality of Life and Reduce Hospital Use
Status: COMPLETED
Conditions: ED Patients With Chronic Medical Illnesses
Interventions: BEHAVIORAL: ED-to-home care transition intervention|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Vaccine Trial for Clear Cell Sarcoma, Pediatric Renal Cell Carcinoma, Alveolar Soft Part Sarcoma and Children With Stage IV Melanoma
Status: COMPLETED
Conditions: Sarcoma, Clear Cell|Sarcoma, Alveolar Soft Part|Renal Cell Carcinoma|Melanoma
Interventions: BIOLOGICAL: GVAX
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Minimal Injuries From Esophagus Detected by Optical Enhancement System™ Associated to Optical Magnification HD Scopes
Status: COMPLETED
Conditions: Non Erosive Reflux Disease|GERD
Interventions: DEVICE: Optical Enhancement|DEVICE: Optical Enhancement with optical magnification|DEVICE: Optical magnification without Optical enhancement
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Persistence of Bactericidal Antibodies in Adults Who Received a Booster Dose of Menactra® Approximately 4 Years Earlier
Status: COMPLETED
Conditions: Meningitis|Meningococcal Meningitis|Meningococcal Infections
Interventions: BIOLOGICAL: Meningococcal (Groups A, C, Y, and W-135) Polysaccharide Diphtheria Toxoid Conjugate Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Subpectoral Bupivacaine for Pain Management in Adolescent Reduction Mammaplasty
Status: RECRUITING
Conditions: Macromastia|Post-operative Pain
Interventions: DRUG: Marcaine 0.25 % Injectable Solution|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Late-presenting Hip Dislocation in Non-ambulatory Children With Cerebral Palsy: A Comparison of Three Procedures
Status: RECRUITING
Conditions: Cerebral Palsy, Spastic
Interventions: PROCEDURE: Hip reconstruction surgery.|PROCEDURE: Proximal femoral resection|PROCEDURE: Proximal femoral valgus ostetomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Two Cohort Study to Look at the Metabolites of GSK221149, the Metabolism of GSK221149 Administered With a High Fat Meal and With Ketoconazole
Status: COMPLETED
Conditions: Obstetric Labour, Premature
Interventions: DRUG: GSK221149 750 mg|DRUG: Ketoconazole|DRUG: GSK221149 100 mg|DRUG: GSK221149 750 mg Fasted|DRUG: GSK221149 750 mg + Food
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Ibrutinib in Treating Minimal Residual Disease in Patients With Chronic Lymphocytic Leukemia After Front-Line Therapy
Status: ACTIVE_NOT_RECRUITING
Conditions: Stage I Chronic Lymphocytic Leukemia|Stage II Chronic Lymphocytic Leukemia|Stage III Chronic Lymphocytic Leukemia|Stage IV Chronic Lymphocytic Leukemia
Interventions: DRUG: Ibrutinib|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Safety and Immune Response of an Adenovirus-Based HIV Vaccine in HIV-Uninfected Adults
Status: COMPLETED
Conditions: HIV Infections
Interventions: BIOLOGICAL: Ad26.ENVA.01 (rAd26)|BIOLOGICAL: Placebo Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Living With a Long-Term Condition Study
Status: RECRUITING
Conditions: Asthma|Atrial Fibrillation|Cancer|Cerebrovascular Disorders|Stroke|CKD|Copd|Fibromyalgia|Pain|Heart Diseases|Heart Disease Chronic|Dementia|Diabetes|Epilepsy|Heart Failure|High Blood Pressure|Hypertension|Hiv|AIDS|IBD|IBS|Liver Diseases|Long COVID|Lupus Erythematosus|Multiple Sclerosis|Obesity|Osteoarthritis|Arthritis|Rheumatoid Arthritis|Osteoporosis|Parkinson Disease|Sickle Cell Disease|Hepatitis|Endometriosis|PCOS|Neurological Disorder|POTS - Postural Orthostatic Tachycardia Syndrome|MND (Motor Neurone DIsease)|Cystic Fibrosis|Migraine|Spondylitis|Celiac Disease|Hidradenitis Suppurativa|Eczema|ME/CFS
Interventions: DIAGNOSTIC_TEST: Living with LTC Questionnaire
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of the Effects of Pantoprazole on Levels of Prescribed Psychiatric Medications
Status: WITHDRAWN
Conditions: Psychotic Disorders|Gastroesophageal Reflux
Interventions: DRUG: Pantoprazole|DRUG: Pantoprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Non-inflatable Supraglottic Airway (NI-SGA) vs. Face Mask (FM) as a Primary Interface Device for Neonatal Resuscitation
Status: WITHDRAWN
Conditions: Neonatal Resuscitation
Interventions: DEVICE: Non-inflatable supraglottic airway|DEVICE: Face Mask|DEVICE: T-Piece Resuscitator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Capecitabine and Oxaliplatin in Adenocarcinoma of the Small Bowel and Ampulla of Vater
Status: COMPLETED
Conditions: Gastrointestinal Cancer
Interventions: DRUG: Capecitabine|DRUG: Oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility Study of Balloon Eustachian Tuboplasty (BET)
Status: WITHDRAWN
Conditions: Retraction of the Pars Tensa of the Tympanic Membrane|Eustachian Tube Dysfunction|Retraction Pocket of the Tympanic Membrane
Interventions: DEVICE: Bielefeld balloon
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Improving Quality by Maintaining Accurate Problems in the EHR
Status: COMPLETED
Conditions: Asthma|Atrial Fibrillation|Chronic Obstructive Pulmonary Disease|Coronary Artery Disease|Congestive Heart Failure|Hyperlipidemia|Hypertension|Myocardial Infarction|Sickle Cell Disease|Sleep Apnea|Smoking|Stroke|Tuberculosis
Interventions: OTHER: Problem List Suggestion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Comparison of Total and Partial Fundoplication During Surgery of Patients With Gastroesophageal Reflux Disease
Status: COMPLETED
Conditions: Reflux, Gastroesophageal
Interventions: PROCEDURE: Nissen|PROCEDURE: Toupét
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hippocampus-Avoidance Whole-Brain Radiation Therapy With Simultaneous Integrated Boost for BMs of NSCLC
Status: COMPLETED
Conditions: Brain Metastases|Non-small Cell Lung Cancer
Interventions: RADIATION: ippocampus-Avoidance Whole-Brain Radiation Therapy With Simultaneous Integrated Boost
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Biomarker Levels in Gingival Crevicular Fluid of Patients With Different Periodontal Diseases
Status: COMPLETED
Conditions: Periodontal Diseases
Interventions: DIAGNOSTIC_TEST: GCF obtaining
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Correlation Between Cognitive Function and Relapse of Schizophrenia Regarding Dose Reduction
Status: COMPLETED
Conditions: Schizophrenia Relapse
Interventions: DRUG: reduction of risperidone, haloperidol, olanzapine, quetiapine, aripiprazole, paliperidone, levomepromazine, perphenazine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Cohort Study of Rb-82 Myocardial PET Imaging to Evaluate Coronary Microvascular Dysfunction in Men With Prostate Cancer Receiving Androgen-Deprivation Therapy
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DEVICE: myocardial PET imaging
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: European Health Economic Trial on Home Monitoring in ICD and CRT-D Patients (EuroEco)
Status: TERMINATED
Conditions: Ventricular Fibrillation|Tachycardia, Ventricular|Ventricular Flutter
Interventions: DEVICE: Home Monitoring provided by Biotronik ICD and CRT-D devices|DEVICE: No Home Monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Self-Management for Anxiety, Depression and Somatoform Disorders
Status: COMPLETED
Conditions: Anxiety Depression (Mild or Not Persistent)|Major Depressive Disorder, Single Episode, Unspecified|Neurotic, Stress-related and Somatoform Disorders
Interventions: BEHAVIORAL: Psychosocial Counseling|BEHAVIORAL: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fed Bioequivalence Study of Fenofibric Acid Versus TriCor® (Fenofibrate)
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Fenofibric Acid (Fibricor™) 105 mg Tablet|DRUG: Fenofibrate (Tricor®) 145 mg Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Longitudinal Monitoring of Cerebral Connectivity 3T MRI in Patients With a Transcient Global Amnesia
Status: TERMINATED
Conditions: Amnesia
Interventions: PROCEDURE: achieving a neuropsychological examination in the acute amnesic phase|PROCEDURE: Neurological consultation with neuropsychological evaluation|RADIATION: MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Implementing Enhanced Recovery After Surgery (ERAS) Protocol in Patients Undergoing Minimal Invasive Esophagectomy
Status: NOT_YET_RECRUITING
Conditions: Esophageal Diseases|Esophagostomy Complication
Interventions: OTHER: Enhanced Recovery After Surgery (ERAS) protocol in minimal invasive esophagectomy|OTHER: standard of care approaches in minimal invasive esophagectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Seminal TEX101 as a Predictor of Recovery of Spermatogenesis in Azoospermic Men With Palpable Varicocele
Status: COMPLETED
Conditions: Azoospermia, Nonobstructive|Varicocele
Interventions: PROCEDURE: micro-surgical varicocelectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Pomegranate to Reduce Maternal and Fetal Oxidative Stress and to Improve Outcome in Pregnancies Complicated With Preterm Premature Rupture of Membranes
Status: UNKNOWN
Conditions: PPROM
Interventions: DIETARY_SUPPLEMENT: pomegranate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Recombinant Human-Mouse Chimeric Anti-CD20 Monoclonal Antibody to Treat Non-hodgkin's Lymphoma
Status: COMPLETED
Conditions: Diffuse Large B Cell Lymphoma
Interventions: DRUG: CHOP combined with CMAB304|DRUG: CHOP, CMAB304
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Pharmacokinetics of 4-MUST, Tablets, 128 mg (Valenta Pharm JSC) During Single and Multiple Oral Administration in Healthy Volunteers
Status: RECRUITING
Conditions: Cholecystitis
Interventions: DRUG: 4-MUST, 1 tablet|DRUG: 4-MUST, 2 tablets|DRUG: 4-MUST, 3 tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Phase 3 IGIV, 10% in Alzheimer´s Disease
Status: TERMINATED
Conditions: Alzheimer´s Disease
Interventions: BIOLOGICAL: Immune Globulin Intravenous (Human), 10% Solution|BIOLOGICAL: Human albumin 0.25%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: ErbB2 Over-expressing Metastatic Breast Cancer Study Using Paclitaxel, Trastuzumab, and Lapatinib
Status: TERMINATED
Conditions: Neoplasms, Breast
Interventions: DRUG: lapatinib|DRUG: paclitaxel|DRUG: trastuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intestinal Microbiota Impact for Prognosis and Treatment Outcomes in Early Luminal Breast Cancer and Pancreatic Cancer Patients
Status: RECRUITING
Conditions: Breast Cancer|Pancreas Cancer
Interventions: DRUG: mFOLFIRINOX|DRUG: Doxorubicin|DRUG: Cyclophosphamid|DRUG: Paclitaxel|DRUG: Carboplatin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Long-Term Extension Study of KRN23 in Adult Subjects With X-Linked Hypophosphatemia (XLH)
Status: COMPLETED
Conditions: X-Linked Hypophosphatemia
Interventions: BIOLOGICAL: KRN23
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Intranasal Kovacaine Mist, Tetracaine Alone, and Placebo for Anesthetizing Maxillary Teeth in Adults
Status: COMPLETED
Conditions: Anesthesia
Interventions: DRUG: Tetracaine HCl 3% and Oxymetazoline HCl 0.05%|DRUG: Tetracaine HCl 3%|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SpeakFree Heat and Moisture Exchanger (HME)
Status: RECRUITING
Conditions: Laryngeal Cancer|Laryngectomy
Interventions: DEVICE: SpeakFree HME Hands Free Valve|OTHER: Digital Occlusion|DEVICE: Digital Depression HME
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Cold Dissection Versus Electrocautery Dissection in Endoscopic Nipple-Sparing Mastectomy and Immediate Implant-Based Reconstruction: A Randomized Controlled Trial
Status: RECRUITING
Conditions: Breast Neoplasms
Interventions: PROCEDURE: Cold dissection|PROCEDURE: Electrocautery Dissection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Anlotinib Plus Platinum Plus Pemetrexed in T790M-negative NSCLC
Status: UNKNOWN
Conditions: Lung Cancer Metastatic
Interventions: DRUG: anlotinib 8mg + AP/PC|DRUG: anlotinib 10mg + AP/PC|DRUG: anlotinib 12mg + AP/PC|DRUG: anlotinib + AP/PC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Occlusal Outcomes by OGS After a Finishing Protocol
Status: COMPLETED
Conditions: Malocclusion|Orthodontics
Interventions: DEVICE: T1 before aligner|OTHER: T2 after the aligner|OTHER: Historic control group
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: PENG Block With Two Diffirent Volume
Status: COMPLETED
Conditions: Pain, Acute|Postoperative Pain|Hip Fractures
Interventions: OTHER: Ultrasound guided PENG block with 20 mL Local Anesthetic solution|OTHER: Ultrasound guided PENG block with 30 mL Local Anesthetic solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: ERAS (Enhanced Recovery After Surgery) Protocol Implementation in Piedmont Region for Colorectal Cancer Surgery
Status: COMPLETED
Conditions: Colorectal Cancer|Quality Improvement|Perioperative Care|Recovery of Function
Interventions: PROCEDURE: ERAS protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Treatment of Cerebellar Ataxia With Mesenchymal Stem Cells
Status: COMPLETED
Conditions: Cerebellar Ataxia
Interventions: BIOLOGICAL: Allogeneic adult adipose-derived mesenchymal stem cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testing The Effectiveness Of Celecoxib In Patients With Painful Sore Throat
Status: COMPLETED
Conditions: Pharyngitis
Interventions: DRUG: Celecoxib|DRUG: Celecoxib|DRUG: celecoxib|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluate Safety and Efficacy of Pronavi Microcatheter for Use in Endovascular Interventions
Status: COMPLETED
Conditions: Coronary Artery Disease|Peripheral Arterial Disease
Interventions: DEVICE: microcatheter
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Antibiotic Regimen (Meropenem Versus Meropenem+Moxifloxacin)in the Treatment of Severe Sepsis and Septic Shock
Status: COMPLETED
Conditions: Severe Sepsis|Septic Shock
Interventions: DRUG: meropenem|DRUG: meropenem, moxifloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improving Health Awareness Using Social Network Interventions
Status: ACTIVE_NOT_RECRUITING
Conditions: Health Knowledge, Attitudes, Practice
Interventions: BEHAVIORAL: Digital Sensors for Population Awareness about Health Issues using Social Media
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Breastfeeding in Infancy and Food Intake in Preschool-Aged Children
Status: COMPLETED
Conditions: Childhood Obesity|Breastfeeding
Interventions: OTHER: High Energy Density Preload|OTHER: Low Energy Density Preload
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Bioavailability of Dexmedetomidine After Intranasal Administration
Status: COMPLETED
Conditions: Sedation
Interventions: DRUG: Intravenous dexmedetomidine|DRUG: Intranasal dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety Study for Treatment of Wet Macular Degeneration Using the TheraSight(TM) Ocular Brachytherapy System
Status: UNKNOWN
Conditions: Macular Degeneration|Choroidal Neovascularization
Interventions: DEVICE: Ocular Brachytherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of CS-3150 in Combination With ARB or ACE Inhibitor in Hypertensive Patients With Moderate Renal Impairment
Status: COMPLETED
Conditions: Hypertension With Moderate Renal Impairment
Interventions: DRUG: CS-3150
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: pK of a Novel 200 mg Ibuprofen Medicated Plaster
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Ibuprofen 200 mg TEPI Medicated Plaster|DRUG: Aktren® 200 mg überzogene Tabletten (Ibuprofen)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Safety, Tolerability and Pharmacokinetics of Two Different Doses of Alpha1-Proteinase Inhibitor Subcutaneous (Human) 15% in Participants With Alpha1-Antitrypsin Deficiency
Status: RECRUITING
Conditions: Alpha1-Antitrypsin Deficiency
Interventions: BIOLOGICAL: Alpha-1 15%|BIOLOGICAL: Liquid Alpha1-Proteinase Inhibitor (Human)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SENSE (Subcutaneous and Epidural Neuromodulation System Evaluation) Study
Status: TERMINATED
Conditions: Failed Back Surgery Syndrome|Post-Laminectomy Syndrome|Low Back Pain
Interventions: DEVICE: SCS and PNfS|DEVICE: SCS Alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of NB-UVB on the Tissue Level of IL 15 and IL-15Rα in Active Non Segmental Vitiligo Cases.
Status: COMPLETED
Conditions: Active Non Segmental Vitiligo
Interventions: RADIATION: Narrow band ultraviolet B
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effect of Obesity and Weight Loss in Heart Failure With Reduced Ejection Fraction.
Status: RECRUITING
Conditions: Heart Failure|Heart Failure With Reduced Ejection Fraction|Obesity|Overweight
Interventions: OTHER: Diet intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Constipation in Functional Dyspepsia
Status: COMPLETED
Conditions: Dyspepsia|Constipation
Interventions: BEHAVIORAL: Biofeedback|DIETARY_SUPPLEMENT: Fiber supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Movement and Music Programme in Early Childhood Education and Care (The MoviMusi Study Protocol)
Status: RECRUITING
Conditions: Fundamental Motor Skills|Physical Activity|Music Intervention
Interventions: BEHAVIORAL: A multi-component, multi-level programme (MoviMusi)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Artesunate in Preemptive Treatment of Human Cytomegalovirus (CMV) in Stem Cell Transplant Recipients
Status: COMPLETED
Conditions: Cytomegalovirus Infections
Interventions: DRUG: Artesunate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Treatment of Cartilaginous Lesions and Concomitant Anterior Cruciate Ligament Reconstruction
Status: RECRUITING
Conditions: Cruciate Ligament Rupture|Cartilage Injury
Interventions: PROCEDURE: Nanofractures|PROCEDURE: no treatment cartilaginous lesions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Ramucirumab (LY3009806) Plus MEDI4736 in Participants With Advanced Gastrointestinal or Thoracic Malignancies
Status: COMPLETED
Conditions: Gastric Cancer|Gastroesophageal Junction Adenocarcinoma|Non-Small Cell Lung Cancer|Hepatocellular Carcinoma
Interventions: DRUG: Ramucirumab|DRUG: MEDI4736
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Metabolism of Low Carbohydrate and Ketogenic Diet
Status: COMPLETED
Conditions: Diabetic Kidney Disease|Cognitive Function|Weight Loss|Diabetic Control|Type2 Diabetes
Interventions: OTHER: mHealth + low-fat diet|OTHER: mHealth + low-carb/ketogenic diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effectiveness of Dalteparin Therapy as Intervention in Recurrent Pregnancy Loss
Status: COMPLETED
Conditions: Abortion, Habitual
Interventions: DRUG: Fragmin P Forte (dalteparin sodium)|DIETARY_SUPPLEMENT: Multivitamin supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I/IIa AERAS-456 in HIV-Negative Adults With & Without Latent Tuberculosis Infection (C-035-456)
Status: COMPLETED
Conditions: Latent Tuberculosis Bacteriology and Histology Unknown|Latent Tuberculosis
Interventions: BIOLOGICAL: H56ug/IC31nmol|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Idiopathic Bilateral Vestibulopathy: Peripheral Vestibular Disorders and Their Repercussions
Status: ACTIVE_NOT_RECRUITING
Conditions: Idiopathic Bilateral Vestibulopathy
Interventions: OTHER: Assessment of postural stability and active motion perception|OTHER: Cognitive tests|OTHER: Eccentric axis rotation|OTHER: Osteodensitometry|OTHER: Posturography|OTHER: Vestibulo-sympathetic regulation test|OTHER: Sleep quality assessment|OTHER: Representation of space and time assessment|OTHER: Influence of vestibular information on the bodily self-consciousness|OTHER: 3 Tesla MRI
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Role of Herbs in the Management of Asthma
Status: UNKNOWN
Conditions: Bronchial Asthma
Interventions: DRUG: Polyherbal|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Syndactyly Versus Closed Reduction in 5th Metacarpal Neck Fracture
Status: COMPLETED
Conditions: Metacarpal Fracture
Interventions: PROCEDURE: Syndactyly|PROCEDURE: Reduction and inmobilization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of Sleep Apnea on Risk of Atrial Fibrillation
Status: COMPLETED
Conditions: Sleep Apnea|Atrial Fibrillation
Interventions: OTHER: Continuous Positive Airway Pressure
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PROSPECT: Chemotherapy Alone or Chemotherapy Plus Radiation Therapy in Treating Patients With Locally Advanced Rectal Cancer Undergoing Surgery
Status: ACTIVE_NOT_RECRUITING
Conditions: Colorectal Cancer
Interventions: DRUG: FOLFOX (chemotherapy)|OTHER: 5 FUCMT (chemoradiation)|PROCEDURE: surgery|PROCEDURE: magnetic resonance imaging or endorectal ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Brain Anatomy on the Efficacy of Brain Stimulation Therapy
Status: COMPLETED
Conditions: Healthy
Interventions: DEVICE: intermittent theta burst stimulation (iTBS) with sham and then active stimulation over bicep muscle|DEVICE: intermittent theta burst stimulation (iTBS) with sham and then active stimulation over finger muscle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pre-operative IL13-PE38QQR in Patients With Recurrent or Progressive Malignant Glioma
Status: COMPLETED
Conditions: Malignant Glioma|Glioblastoma Multiforme|Anaplastic Astrocytoma|Mixed Oligoastrocytoma
Interventions: DRUG: IL13-PE38QQR|PROCEDURE: targeted fusion protein therapy|PROCEDURE: surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Different Types of Foot Orthosis in Adults With Compensatory Forefoot Varus
Status: TERMINATED
Conditions: Forefoot Varus|Flat Feet
Interventions: OTHER: Arch support orthoses with forefoot medial wedge|OTHER: Arch support orthoses|OTHER: Flat insole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Implementing Circulating Tumor DNA Analysis at Initial Diagnosis to Improve Management of Advanced NSCLC Patients
Status: RECRUITING
Conditions: Non Small Cell Lung Cancer|Advanced Solid Tumor
Interventions: DIAGNOSTIC_TEST: EGFR gene mutation analysis on liquid biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Bioclinical Study of Scalp Photoaging of a Population Male Over 65 Years Old.
Status: TERMINATED
Conditions: Skin Aging|Skin Cancer
Interventions: PROCEDURE: biopsy|DIAGNOSTIC_TEST: blood sample|DIAGNOSTIC_TEST: questionnaire on sun exposure|DIAGNOSTIC_TEST: examination of the scalp|DIAGNOSTIC_TEST: Norwood scale|DIAGNOSTIC_TEST: questionnaire of clinicals signs|DIAGNOSTIC_TEST: scinexa score|DIAGNOSTIC_TEST: questionnaire of the history of the hair loss
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: ESP Block VS TAP in Laparoscopic Hysterectomy
Status: COMPLETED
Conditions: Hysterectomy
Interventions: DRUG: Liposomal bupivacaine|DRUG: bupivacaine, 0.125%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Patent Versus Generic Clopidogrel in Acute Coronary Syndrome
Status: UNKNOWN
Conditions: Acute Coronary Syndrome
Interventions: DRUG: Generic clopidogrel|DRUG: Patent clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Cervical Multifidus Muscle Area on Interlaminar Epidural Steroid Injection Outcomes
Status: NOT_YET_RECRUITING
Conditions: Cervical Radiculopathy
Interventions: OTHER: Cervical multifidus muscle area measurement at 3 levels (C4-C5, C5-C6, C6-C7)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Instability in the Lumbar Spine of Patients With Age Related Changes and Narrowing of the Spinal Canal (Spinal Stenosis)
Status: COMPLETED
Conditions: Degenerative Lumbar Spinal Stenosis|Degenerative Spondylolisthesis
Interventions: PROCEDURE: decompression|PROCEDURE: fusion
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of Glycaemic Control Using GlucoTab® With Insulin Degludec in Hospitalized Patients With Diabetes Mellitus Type 2
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DEVICE: GlucoTab|DRUG: Insulin Degludec
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Low-Dose vs High-Dose Epidural Fentanyl on Gastric Emptying - A Prospective Double-Blinded Randomized Controlled Trial
Status: UNKNOWN
Conditions: Effects of; Anesthesia, Spinal and Epidural, in Pregnancy|Aspiration
Interventions: DRUG: Low Dose Fentanyl|DRUG: High Dose Fentanyl|DEVICE: Gastric Ultrasonography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Fructose Metabolizing Enzymatic Product in Fructose Malabsorption
Status: COMPLETED
Conditions: Fructose Malabsorption
Interventions: DIETARY_SUPPLEMENT: Fructosin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Renal Denervation to Treat Heart Failure With Preserved Ejection Fraction
Status: RECRUITING
Conditions: Heart Failure With Preserved Ejection Fraction|Hypertension, Renal
Interventions: PROCEDURE: Renal Denervation|PROCEDURE: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Preoperative Simulator Warmup on Intraoperative Robotic Surgical Skills
Status: COMPLETED
Conditions: Robotic Hysterectomy (Benign Indications/Early-stage Cancer)
Interventions: OTHER: Preoperative warm-up on simulator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Evaluation of the Efficacy of Probiotics in Chronic Periodontitis Patients
Status: COMPLETED
Conditions: Chronic Periodontitis
Interventions: DRUG: Probiotic|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Ubiquinol on Mitochondrial Oxidative Capacity in Statin Patients Using 31PMRS
Status: COMPLETED
Conditions: Myopathy|HMG COA Reductase Inhibitor Adverse Reaction|Hypercholesterolemia
Interventions: DIETARY_SUPPLEMENT: ubiquinol|DIETARY_SUPPLEMENT: placebo|DRUG: statin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Almonertinib as Upfront Treatment for Uncommon EGFR Mutation Harboring Non-Small-Cell Lung Cancer Patients: A Multicenter, Open-Label, Phase II Trial
Status: UNKNOWN
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: Almonertinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Oral Seltorexant as an add-on Medication to an Antidepressant on On-road Driving Performance in Participants With Major Depressive Disorder
Status: COMPLETED
Conditions: Depressive Disorder, Major
Interventions: DRUG: Seltorexant Dose 1|DRUG: Seltorexant Dose 2|DRUG: Placebo|DRUG: Zopiclone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Randomized, Double-Blind Clinical Trial for Parkinson's Disease (Early and Moderate)
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: BIOLOGICAL: HB-adMSCs|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tacrolimus for Malar Edema
Status: UNKNOWN
Conditions: Edema Face
Interventions: DRUG: Tacrolimus Topical 0.1% Topical Ointment|DRUG: Polysporin Ointment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION