pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Testing Tele-Savvy, an On-line Psychoeducation Program for Dementia Family Caregivers
Status: COMPLETED
Conditions: Alzheimer Disease|Dementia
Interventions: BEHAVIORAL: Tele-Savvy|BEHAVIORAL: Healthy Living Education Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: S-ketamin Premedication in Pediatric EENT Surgery
Status: COMPLETED
Conditions: Emotions|Separation Anxiety|Pain, Procedural
Interventions: DRUG: S-ketamine 0.3|DRUG: S-ketamine 0.5|DRUG: S-ketamine 2|DRUG: S-ketamine 1+Dexmedetomidine 1|DRUG: S-ketamine 0.5 +Dexmedetomidine 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: JACTAX LD Drug Eluting Stent Trial
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DEVICE: JACTAX LD DES|DEVICE: TAXUS™ Libertè™ DES
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Digoxin for the Reinduction of Radioiodine Uptake in Metastatic or Locally Advanced Non-medullary Thyroid Carcinoma
Status: COMPLETED
Conditions: Non-Medullary Thyroid Carcinoma
Interventions: DRUG: Digoxin tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Simvast Controlled Release (CR) and Zocor in Chronic Kidney Disease(CKD) Stage 3, 4 and 5 Patients With Hyperlipidemia
Status: UNKNOWN
Conditions: Chronic Kidney Disease|Hyperlipidemia
Interventions: DRUG: Simvast CR|DRUG: Zocor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Anti-5T4 CAR-raNK Cell Therapy in Locally Advanced or Metastatic Solid Tumors
Status: RECRUITING
Conditions: Locally Advanced or Metastatic Solid Tumors
Interventions: BIOLOGICAL: Anti-5T4 CAR-raNK Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Advanced Cognitive Stimulation Therapy (ACST)
Status: UNKNOWN
Conditions: DEM|Dementia|Dementia, Vascular|Dementia, Mixed|Dementia With Lewy Bodies|Dementia Frontal|Dementia Severe|Dementia Moderate|Dementia of Alzheimer Type
Interventions: OTHER: Advanced Cognitive Stimulation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Social Networks and Methadone Maintenance Treatment Retention and Antiretroviral Therapy Retention in Tanzania
Status: RECRUITING
Conditions: Opioid-use Disorder|Adherence, Medication|HIV Infections
Interventions: BEHAVIORAL: Supportive care through community support persons
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Application of Hyaluronic Acid in the Treatment of Periodontitis
Status: RECRUITING
Conditions: Periodontal Bone Loss
Interventions: PROCEDURE: Hyaluronic acid|PROCEDURE: No-hyaluronic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Phase I Combination With Vinorelbine or Gemcitabine Plus Cisplatin in Locally Advanced or Metastatic NSCLC
Status: COMPLETED
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: Zactima (ZD6474)|DRUG: Vinorelbine plus cisplatin|DRUG: Gemcitabine plus cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Osteopathic Manipulative Treatment for Gastro-oesophageal Reflux Disease
Status: RECRUITING
Conditions: Gastro-oesophageal Reflux Disease
Interventions: OTHER: Osteopathic manipulative treatment (OMT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigation of Optimal Dosage Regimen for HRS9531 Tablets in Healthy Subjects
Status: NOT_YET_RECRUITING
Conditions: Overweight or Obese, Type 2 Diabetes
Interventions: DRUG: HRS9531 tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Sodium Phenylbutyrate (ACER-001) for the Treatment of Patients With Medium Chain Acyl-CoA Dehydrogenase Deficiency (MCADD)
Status: RECRUITING
Conditions: Medium-chain Acyl-CoA Dehydrogenase Deficiency
Interventions: DRUG: Sodium phenylbutyrate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Capecitabine Plus Toripalimab Maintenance Therapy in Metastatic Nasopharyngeal Carcinoma After First-line Treatment
Status: NOT_YET_RECRUITING
Conditions: Metastatic Nasopharyngeal Carcinoma
Interventions: DRUG: Capecitabine plus toripalimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Tolerance to the Treatment of Obstructive Sleep Apnea by Shear Wave Inducer Collar (ET-SAOS-OC)
Status: COMPLETED
Conditions: Sleep Apnea
Interventions: DEVICE: shearing wave collar
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Intraoperative Use of 20% Albumin Combined With Ringer Lactate Versus Ringer Lactate During Cytoreductive Surgery With Hyperthermic Intraperitoneal Chemotherapy
Status: NOT_YET_RECRUITING
Conditions: Peritoneal Neoplasms|Hyperthermic Intraperitoneal Chemotherapy|Intraoperative Care|Fluid Therapy|Postoperative Complications
Interventions: OTHER: Intra-operative albumin administration|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of COVID-19 Pandemic on a Health Care System: Case Study of the CirculatORy System in LiThuania
Status: COMPLETED
Conditions: Cardiovascular Diseases
Interventions: OTHER: Data collection on outpatient care|OTHER: Data collection on hospitalisation|OTHER: Data collection on cardiovascular mortality|OTHER: Data collection of patients presenting to the tertiary care centre with acute coronary syndrome
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Vaccine Therapy With or Without Cryosurgery in Treating Patients With Residual, Relapsed, or Refractory B-Cell Non-Hodgkin Lymphoma
Status: COMPLETED
Conditions: Cutaneous B-cell Non-Hodgkin Lymphoma|Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue|Nodal Marginal Zone B-cell Lymphoma|Adult Diffuse Mixed Cell Lymphoma|Adult Diffuse Small Cleaved Cell Lymphoma|Adult Grade III Lymphomatoid Granulomatosis|Adult Immunoblastic Large Cell Lymphoma|Adult Lymphoblastic Lymphoma|Grade 1 Follicular Lymphoma|Grade 2 Follicular Lymphoma|Grade 3 Follicular Lymphoma|Mantle Cell Lymphoma|Marginal Zone Lymphoma|Small Lymphocytic Lymphoma|Splenic Marginal Zone Lymphoma|Waldenstrom Macroglobulinemia With Nodal Disease
Interventions: BIOLOGICAL: dendritic cell vaccine therapy|PROCEDURE: cryotherapy|BIOLOGICAL: pneumococcal polyvalent vaccine|OTHER: laboratory biomarker analysis|OTHER: immunoenzyme technique|OTHER: immunohistochemistry staining method|BIOLOGICAL: autologous dendritic cell-tumor fusion vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phamacokinetics and Safety Profiles of DA-5210 10/500mg in Healthy Subjects at Fed State
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: DA-5210 10/500mg|DRUG: DA-5210-R 10/500mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Breathing-swallowing Interaction in Chronic Obstructive Pulmonary Disease Patients - Impact of Non Invasive Ventilation
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)|Decompensated COPD With (Acute) Exacerbation
Interventions: OTHER: Spontaneous Breathing|OTHER: Non Invasive Mechanical Ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Atrial Fibrillation: Ablation or Surgical Treatment II: FAST II
Status: TERMINATED
Conditions: Paroxysmal Atrial Fibrillation.
Interventions: PROCEDURE: Percutaneous radiofrequency catheter ablation|PROCEDURE: Mini invasive thoracoscopic radiofrequency ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Direct Endomyocardial Injection of Autologous Bone Marrow Cells to Treat Ischaemic Heart Failure
Status: UNKNOWN
Conditions: Coronary Artery Disease
Interventions: PROCEDURE: Endomyocardial Injection of Autologous Bone Marrow Cells|PROCEDURE: Endomyocardial Injection of Plasma
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Mind-body Intervention for Compulsive Sexual Behavior Disorder
Status: ENROLLING_BY_INVITATION
Conditions: Compulsive Sexual Behavior
Interventions: BEHAVIORAL: Mind-body intervention|BEHAVIORAL: Sham intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Single-arm Pilot Study of Tislelizumab Combined With Anlotinib in Patients With Advanced NSCLC With Driver-negative After Progression to Immunotherapy
Status: NOT_YET_RECRUITING
Conditions: Advanced NSCLC
Interventions: DRUG: Tislelizumab|DRUG: Anlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of the Effect of Empagliflozin (BI 10773) as Single Dose on the QT Interval in Healthy Female and Male Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BI 10773 (low)|DRUG: Moxifloxacin|DRUG: BI 10773 Placebo|DRUG: BI 10773 (high)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Study of the Duration and Efficacy of MYDAYIS on Adult ADHD Symptoms and Executive Function Throughout the Day Into the Early Evening
Status: COMPLETED
Conditions: Attention Deficit-Hyperactivity
Interventions: DRUG: MYDAYIS|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 16 Week Efficacy and 2 Year Long Term Safety and Efficacy of Secukinumab in Patients With Active Ankylosing Spondylitis
Status: COMPLETED
Conditions: Ankylosing Spondylitis
Interventions: DRUG: Secukinumab (75 mg)|DRUG: Secukinumab (150 mg)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Lactulose on Minimal Hepatic Encephalopathy and Health-Related Quality of Life
Status: COMPLETED
Conditions: Minimal Hepatic Encephalopathy|Hepatic Encephalopathy
Interventions: DRUG: Lactulose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Financial Health Incentives to Promote Physical Activity Among Hospital Employees: A Randomized Control Trial
Status: COMPLETED
Conditions: Physically Inactive Hospital Employees
Interventions: BEHAVIORAL: Wellness program|DEVICE: Accelerometer|BEHAVIORAL: Incentive
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Immune Response in Adults to PrEP and Simulated Booster PEP With a New CPRV
Status: COMPLETED
Conditions: Efficacy of the New CPRV
Interventions: BIOLOGICAL: New Chromatographically Purified Vero-cell Rabies vaccine(new CPRV).
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Bardoxolone Methyl Evaluation in Patients With Chronic Kidney Disease and Type 2 Diabetes
Status: TERMINATED
Conditions: Renal Insufficiency, Chronic|Diabetes Mellitus, Type 2
Interventions: DRUG: Placebo|DRUG: Bardoxolone Methyl: 20 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: HOPE-Epilepsy Trial
Status: SUSPENDED
Conditions: Epilepsy
Interventions: DIETARY_SUPPLEMENT: Omega 3 fatty acids|DIETARY_SUPPLEMENT: corn oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety of XELOX Combined With GLS-010 and Lenvatinib in Advanced AFP-positive Gastric Cancer Patients
Status: UNKNOWN
Conditions: First-line Treatment|Advanced Gastric Carcinoma
Interventions: DRUG: Lenvatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anti-HLA Immunization And Immunosuppressive Therapy Management In Kidney Transplant Patients Returning to Dialysis
Status: UNKNOWN
Conditions: Kidney Transplantation|Immunosuppressive Agents|HLA Sensitization|Dialysis
Interventions: DRUG: management of immunosuppressive therapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Prevention of Nosocomial Infection by Decontamination of the Naso- and Oropharynx With Chlorhexidine (NONI Trial)
Status: COMPLETED
Conditions: Nosocomial Infection|Respiratory Tract Infection|Surgical Site Infection
Interventions: DRUG: Chlorhexidine gluconate (drug) vs placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Phase II Trial of Revlimid® and Rituximab for Relapsed or Refractory Chronic Lymphocytic Leukemia (CLL)
Status: COMPLETED
Conditions: Chronic Lymphocytic Leukemia|CLL
Interventions: DRUG: Revlimid|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunologic Response to Influenza Vaccination in Children and Adolescents
Status: COMPLETED
Conditions: Influenza, Human|Immune Response
Interventions: BIOLOGICAL: Flucelvax inactivated influenza vaccine|BIOLOGICAL: Fluzone inactivated influenza vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Nutritional Intervention for Age-related Muscular Function and Strength Losses
Status: COMPLETED
Conditions: Muscle Strength|Sarcopenia
Interventions: DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: Vitamin D|DIETARY_SUPPLEMENT: Beta-hydroxy-Beta-methylbutyrate|DRUG: Beta-hydroxy-Beta-methylbutyrate and Vitamin D
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized, Non-inferiority Trial Comparing SMILE and LASIK
Status: UNKNOWN
Conditions: Myopia|Astigmatism|Hypermetropia
Interventions: PROCEDURE: Femtosecond LASIK|PROCEDURE: Small incision lenticule extraction (SMILE)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Glucose/Ischemic Preconditioning on Reperfusion Injury in Deceased-Donor Liver Transplantation
Status: TERMINATED
Conditions: Liver Transplantation
Interventions: PROCEDURE: Glucose/Ischemic Preconditioning Pre-treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Methotrexate in Symptomatic Knee Osteoarthritis
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DRUG: Methotrexate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Reducing Self-Stigma Among Individuals With History of Childhood Maltreatment: A Cross-Cultural Lens
Status: NOT_YET_RECRUITING
Conditions: Stigma, Social|Child Abuse|Child Neglect|Help-Seeking Behavior
Interventions: BEHAVIORAL: Video
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Oscillations of Dietary Fat/Carbohydrate Intake Over Interval of 3 to 4 Days
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: Dietary fat/intake of carbohydrate|BEHAVIORAL: Spontaneous oscillations of dietary fat/intake of carbohydrate in relation to energy intake.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fluticasone Furoate Nasal Spray Versus Oral Fexofenadine
Status: COMPLETED
Conditions: Rhinitis, Allergic, Seasonal
Interventions: DRUG: fluticasone furoate, fexofenadine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Safety & Efficacy of a Combination of Niacin ER & Simvastatin in Patients With Dyslipidemia (OCEANS)
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DRUG: Niacin Extended-Release and simvastatin Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Role of Vibrational Spectroscopy in the Assessment of Vulval Disease
Status: SUSPENDED
Conditions: Normal Vulval Skin|Lichen Sclerosus|High Grade Dysplasia - Usual Type ('VIN 2-3')|High Grade Dysplasia - Differentiated Type ('VIN 2-3')|Squamous Cell Carcinoma|Epithelial Hyperplasia Without Atypia|Atypia Not Otherwise Specified/ Low Grade Dysplasia ('VIN 1')|Pagets Disease of the Vulva
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Cord Blood Derived Anti-CD19 CAR-Engineered NK Cells for B Lymphoid Malignancies
Status: UNKNOWN
Conditions: Acute Lymphocytic Leukemia|Chronic Lymphocytic Leukemia|Non Hodgkin's Lymphoma
Interventions: DRUG: Fludarabine + Cyclophosphamide + CAR-NK-CD19 Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Goal-directed Fluid Therapy on Post-operative Outcomes in Children Undergoing Scoliosis Repair
Status: TERMINATED
Conditions: Scoliosis|Acute Kidney Injury
Interventions: DRUG: Plasmalyte|PROCEDURE: Goal-directed fluid therapy (GDT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Clinical and Stereoradiological Comparison of the Results After Primary Cemented Total Knee Arthroplasty Inserted With or Without the Use of a Tourniquet
Status: WITHDRAWN
Conditions: Osteoarthritis of the Knee
Interventions: PROCEDURE: tourniquet|PROCEDURE: no tourniquet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study To Evaluate The Safety Of Voriconazole As Treatment Of Invasive Aspergillosis (Fungal Infection) And Other Rare Molds In Children
Status: TERMINATED
Conditions: Invasive Aspergillosis
Interventions: DRUG: Voriconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Validation of Algorithms for Basal Insulin Rate Reductions in Type 1 Diabetic Patients Practising Physical Activity in Real Life Conditions
Status: COMPLETED
Conditions: Diabetes Mellitus, Type I|Adjustment of Basal Insulin Flow Rate During Physical Activity|Adjustment of Prandial Insulin in Case of Physical Activity
Interventions: BEHAVIORAL: Usual algorithm|BEHAVIORAL: Diabrasport algorithm|BEHAVIORAL: Rest|DEVICE: Holter Glycemic Ipro2, Medtronic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Enhancing the Vagal Tone in Prediabetes Individuals
Status: COMPLETED
Conditions: Prediabetes|Autonomic Nervous System Imbalance|Poor Glycemic Control|Psychological Distress
Interventions: OTHER: HRV biofeedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Accelerating Delivery of rheUmatic Heart Disease Preventive iNterventions in Northern Uganda
Status: RECRUITING
Conditions: Rheumatic Heart Disease
Interventions: OTHER: ADUNU program for delivery of RHD care services
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Progesterone Microspheres Pharmacokinetic - Pharmacodynamic (PK-PD) Study
Status: COMPLETED
Conditions: Infertility
Interventions: DRUG: Progesterone|DRUG: Progesterone|DRUG: Progesterone|DRUG: Progesterone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: NiteCAPP: Web-based Interventions for Insomnia in Rural Dementia Caregivers
Status: RECRUITING
Conditions: Insomnia|Dementia
Interventions: BEHAVIORAL: NiteCAPP CARES|BEHAVIORAL: NiteCAPP SHARES
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: HDAC Inhibitor Vorinostat (SAHA) With Capecitabine (Xeloda) Using a New Weekly Dose Regimen for Advanced Breast Cancer
Status: COMPLETED
Conditions: Advanced Breast Cancer
Interventions: DRUG: Vorinostat
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fed Bioequivalence Study of 2 Metformin 1000 mg Prolonged Release Tablets in 28 Healthy Male and Female Volunteers
Status: COMPLETED
Conditions: Pharmacokinetics
Interventions: DRUG: Metformin 1000 mg Prolonged Release Tablets (JSC Farmak, Ukraine)|DRUG: Glucophage® XR 1000 mg Prolonged Release Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Behavioural Intervention in Mechanically Ventilated Patients
Status: UNKNOWN
Conditions: Noninvasive Ventilation|Chronic Disease Lung
Interventions: BEHAVIORAL: Intervention group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Influence of Aerobic Exercise Training (AET) on Inflammatory Bowel Disease (IBD) in Children and Adolescents
Status: UNKNOWN
Conditions: Ulcerative Colitis|Crohn Disease|Depression|Sleep|Quality of Life|Motor Activity
Interventions: BEHAVIORAL: Aerobic Exercise Training
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of Two Different Thickening Products in Patients With Dysphagia
Status: COMPLETED
Conditions: Dysphagia
Interventions: DIETARY_SUPPLEMENT: Thickenup|DIETARY_SUPPLEMENT: Thickenup Advance
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Targeting the Mechanisms Underlying Cutaneous Neurofibroma Formation in NF1: A Clinical Translational Approach.
Status: RECRUITING
Conditions: Cutaneous Neurofibromas|Neurofibromatosis Type 1|Plexiform Neurofibromas
Interventions: PROCEDURE: Skin Biopsy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Impact of Carrier Solutions for House Dust Mite Allergen on Allergic Reactions
Status: COMPLETED
Conditions: Allergic Rhinitis
Interventions: OTHER: Sodium chloride particles|OTHER: Lactose particles|OTHER: Clean air|OTHER: Sodium chloride particles with house dust mite|OTHER: Lactose particles with house dust mite
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Androgen Deprivation Therapy or Androgen Deprivation Therapy Plus Definitive Treatment (Radiation or Surgery)
Status: UNKNOWN
Conditions: Prostate Cancer
Interventions: DRUG: Bicalutamide|DRUG: goserelin acetate|DRUG: flutamide|DRUG: leuprolide acetate|DRUG: triptorelin|PROCEDURE: Definitive Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Na-GST-1/Alhydrogel Hookworm Vaccine Assessed by Controlled Challenge Infection
Status: COMPLETED
Conditions: Hookworm Infections
Interventions: BIOLOGICAL: Na-GST-1/Alhydrogel|BIOLOGICAL: Na-GST-1/Alhydrogel + CPG 10104|BIOLOGICAL: Na-GST-1/Alhydrogel + GLA-AF|BIOLOGICAL: Placebo|DRUG: Albendazole|OTHER: Necator americanus Larval Inoculum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of Propranolol Versus Atenolol on the Proliferative Phase of Infantile Hemangioma
Status: COMPLETED
Conditions: Hemangioma
Interventions: DRUG: Propranolol|DRUG: Atenolol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Non-Steroidal Anti-Inflammatory Drug Naproxen on Pleural Effusion Formation After Lung Resection
Status: TERMINATED
Conditions: Pleural Effusion|Pleural Effusion Malignant
Interventions: DRUG: Naproxen|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Avastin and Temsirolimus Following Tyrosine Kinase Inhibitor Failure in Patients With Advanced Renal Cell Carcinoma
Status: COMPLETED
Conditions: Renal Cell Carcinoma|Kidney Cancer
Interventions: DRUG: bevacizumab|DRUG: temsirolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety of and Immune Response to Recombinant Live-Attenuated Influenza H6N1 Virus Vaccine Vaccine
Status: COMPLETED
Conditions: Influenza|Virus Diseases
Interventions: BIOLOGICAL: H6N1 Teal HK 97/AA ca recombinant vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Assessing Abuse Potential of Parenteral Buprenorphine/Naloxone in Non-Dependent Opioid Abusers
Status: TERMINATED
Conditions: Opioid-Related Disorders
Interventions: DRUG: Buprenorphine/naloxone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: The Safety and Feasibility of Laparoscopic-assisted Gastrectomy for Advanced Gastric Cancer After Neoadjuvant Chemotherapy
Status: COMPLETED
Conditions: Stomach Neoplasms
Interventions: PROCEDURE: Laparoscopic-assisted gastrectomy with D2 lymphadenectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial of Preoperative CHO Drinks on Postoperative Walking Capacity in Colorectal Surgery
Status: COMPLETED
Conditions: Bowel; Disease, Carbohydrate Absorption|Difficulty Walking|Colorectal Neoplasms
Interventions: DIETARY_SUPPLEMENT: Carbohydrate group|OTHER: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acalabrutinib in CLL and MCL Patients Subjected to Allogeneic Hematopoietic Stem Cell Transplantation (alloSCT)
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Lymphocytic Leukemia|Chronic Graft-versus-host-disease|Mantle Cell Lymphoma|Adverse Event|Response Rate
Interventions: DRUG: Acalabrutinib 2x100 MG Oral Capsule + alloSCT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Letermovir for Primary Prophylaxis of Cytomegalovirus Infection After R+HID-HSCT
Status: NOT_YET_RECRUITING
Conditions: The Incidence of Peripheral Blood CMV Activation and Confirmed Clinically Significant CMV Infection Within 24 Weeks After Transplantation
Interventions: DRUG: Letermovir
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Atezolizumab and Bevacizumab in Combination With TACE for Patients With BCLC B HCC
Status: RECRUITING
Conditions: Hepatocellular Carcinoma|BCLC Stage B Hepatocellular Carcinoma
Interventions: DRUG: Atezolizumab Injection|DRUG: Bevacizumab|COMBINATION_PRODUCT: Transarterial chemoembolization
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase III Study Comparing the Efficacy and Safety of LA-EP2006 and Neulasta®
Status: COMPLETED
Conditions: Neutropenic Complications|Breast Neoplasms|Chemotherapy-induced Neutropenia|Chemotherapeutic Toxicity
Interventions: DRUG: LA-EP2006|DRUG: Neulasta®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study to Evaluate the Extended Overall Survival (OS) Data From PARSIFAL Study (The PARSIFAL-LONG Study)
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Breast Cancer|Advanced Breast Cancer|Luminal Breast Cancer|HER2-negative Breast Cancer|ER-positive Breast Cancer
Interventions: DRUG: Fulvestrant Injectable Product|DRUG: Letrozole 2.5mg|DRUG: Palbociclib 125mg
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Stage I HER2 Positive Invasive Breast Cancer De-escalation Study(IRIS)
Status: RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: capecitabine and trastuzumab|DRUG: endocrine therapy and trastuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of the ToothWave -12 Weeks Calculus Study
Status: COMPLETED
Conditions: Gingivitis|Plaque|Calculus, Dental
Interventions: DEVICE: RF-utilizing powered toothbrush|DEVICE: Control placebo with no RF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Pivotal Study of LIPUS-Brain in Patients With Early Alzheimer's Disease
Status: RECRUITING
Conditions: Alzheimer Disease, Early Onset
Interventions: DEVICE: LIPUS-Brain|DEVICE: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Kaname Coronary Stent System for the Treatment of Patients With Coronary Artery Disease
Status: COMPLETED
Conditions: Coronary Artery Disease|Angioplasty, Transluminal, Percutaneous Coronary
Interventions: DEVICE: implantation of Kaname Cobalt-Chromium coronary stent
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Hyaluronic Acid, With Demineralized Tooth Graft, in Socket Preservation, vs Demineralized Tooth Graft Alone.
Status: ACTIVE_NOT_RECRUITING
Conditions: Alveolar Bone Resorption|Socket Preservation|Bone Resorption
Interventions: PROCEDURE: tooth extraction and socket preservation with demineralized tooth graft|PROCEDURE: tooth extraction and socket preservation with demineralized tooth graft with hyaluronic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: LAL-BR/2001: Study Treatment to Low Risk ALL
Status: COMPLETED
Conditions: Acute Lymphoblastic Leukemia
Interventions: DRUG: Prednisone|DRUG: Vincristine|DRUG: Daunorubicin|DRUG: L-Asparaginase|DRUG: Cyclophosphamide|DRUG: Methotrexate|DRUG: Cytosine Arabinoside|DRUG: Mercaptopurine|DRUG: VP-16
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Ridge Dimensional Changes After Immediate Implantation and Efficacy of This Procedure
Status: COMPLETED
Conditions: Atrophy of Edentulous Alveolar Ridge|Alveolar Ridge Augmentation
Interventions: PROCEDURE: immediate implantation|PROCEDURE: Delayed implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of DWP450 Compared With Botox in Moderate to Severe Glabellar Line
Status: COMPLETED
Conditions: Moderate to Severe Glabellar Line
Interventions: DRUG: Generic equivalent of Clostridium Botulinum A Toxin|DRUG: Botox (Clostridium Botulinum A Toxin)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ultrasound-guided Subclavian Venous Catheterization in Children
Status: COMPLETED
Conditions: Subclavian Venous Catheterization in Children
Interventions: OTHER: Approach for ultrasound-guided subclavian venous catheterization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Extended Drug Utilization Study Among Patients Exposed to Ticagrelor, Clopidogrel and Prasugrel
Status: COMPLETED
Conditions: Bleeding ,Arrhythmias, Heart Failure, Acute Renal Failure, Acute Liver Failure, Dyspnoea, Gout
Interventions: DRUG: Risk of selected safety events
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: First in Man Study Investigating the Biodistribution, the Safety and Optimal Recommended Dose of a New Radiolabelled Monoclonal Antibody Targeting Frizzled Homolog 10
Status: TERMINATED
Conditions: Sarcoma, Synovial
Interventions: DRUG: OTSA101-DTPA-90Y level 1|DRUG: OTSA101-DTPA-90Y level 2|DRUG: OTSA101-DTPA-90Y level 3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of SAR444881 Administered Alone and in Combination With Other Therapeutics in Participants With Advanced Solid Tumors
Status: RECRUITING
Conditions: Cancer|Neoplasm
Interventions: DRUG: SAR444881|DRUG: Pembrolizumab|DRUG: Cetuximab|DRUG: Carboplatin|DRUG: Pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study of Stereotactic Body Radiation Therapy in Patients With T1N0M0 Non-small Cell Lung Cancer (JCOG0403)
Status: COMPLETED
Conditions: T1N0M0 Non-small Cell Lung Cancer
Interventions: PROCEDURE: stereotactic body radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Whole Breast Irradiation With Intensity Modulated Radiotherapy and Simultaneously Integrated Boost for Early Stage Breast Cancer Patients
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: RADIATION: IMRT with an simultaneous integrated boost
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Surgical Treatment of Ischemic Mitral Regurgitation
Status: UNKNOWN
Conditions: Mitral Valve Insufficiency
Interventions: PROCEDURE: CABG|PROCEDURE: CABG combined with MV repair with remodeling annuloplasty rigid ring|PROCEDURE: CABG combined with MV repair with remodeling annuloplasty rigid ring|PROCEDURE: CABG combined with MV repair with remodeling annuloplasty rigid ring and endoventricularplasty of subvalvular apparatus|PROCEDURE: CABG and MV replacement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Novel Balance Program to Improve Balance in People With Parkinson's Disease
Status: RECRUITING
Conditions: Rehabilitation Exercise|Physical Therapy
Interventions: OTHER: Lateral Stepping Exercise 1|OTHER: Active Control Group Exercise 1|OTHER: Active Control Group Exercise 2|OTHER: Active Control Group Exercise 3|OTHER: Active Control Group Exercise 4|OTHER: Lateral Stepping Exercise 2|OTHER: Lateral Stepping Exercise 3|OTHER: Lateral Stepping Exercise 4|OTHER: Lateral Stepping Exercise 5
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: University of Wisconsin hMSC Cell Bank: Bone Marrow Donor Protocol
Status: COMPLETED
Conditions: Graft Versus Host Disease (GVHD)|Acute Myocardial Infarction (AMI)
Interventions: PROCEDURE: Bone marrow aspirate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Correct Mobilization Time After CIED Implantation: A Single-centre, Open-label, Non-inferiority RCT
Status: RECRUITING
Conditions: Pacemaker|Defibrillators, Implantable
Interventions: OTHER: Early mobilization|OTHER: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MiCLASP Post Market Clinical Follow-Up (PMCF) Study
Status: RECRUITING
Conditions: Mitral Regurgitation|Mitral Insufficiency
Interventions: DEVICE: Edwards PASCAL Transcatheter Valve Repair System and Edwards PASCAL Precision Transcatheter Valve Repair System
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phase I, FIH, MTD for MPT0B640, Multi-centre, Open-label, Subject With Locally Advanced or Metastatic Solid Malignancies
Status: WITHDRAWN
Conditions: Advanced Solid Tumor|Metastatic Solid Tumor
Interventions: DRUG: MPT0B640
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ethanol Lock and Risk of Catheter Related Blood Stream Infection in Patients With Haemodialysis Catheter
Status: ACTIVE_NOT_RECRUITING
Conditions: Hemodialysis Catheter-Associated Bacteremia|Hemodialysis Complication
Interventions: DRUG: Ethanol 70%|DRUG: Isotonic saline with heparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effect of Auricular Position on Measurement Values and Comfort in Measuring Body Temperature by Tympanic Method in Pediatric Patients
Status: RECRUITING
Conditions: Body Temperature Changes
Interventions: OTHER: The effect of placing the auricle position on the measurement values and comfort in measurements made with a tympanic membrane thermometer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Effect of Central Insulin on Insulin Sensitivity and Energy Metabolism
Status: COMPLETED
Conditions: Diabetes
Interventions: DRUG: intransal insulin|DRUG: Placebo|DEVICE: taVNS|DEVICE: sham stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Modified Perichondral Approach Thoracoabdominal Nerve Block For Post Cesarean Section
Status: RECRUITING
Conditions: Cesarean Section
Interventions: OTHER: Postoperative analgesia management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Arthrogryposis Multiplex Congenita in Pediatric Age: Correlation Between MUScular MRI and Functional Evaluation
Status: COMPLETED
Conditions: Arthrogryposis Multiplex Congenita|AMC-Arthrogryposis Multiplex Congenita|Pediatric ALL
Interventions: OTHER: No intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pregnancy Registry to Collect Long-Term Safety Data From Women Treated With HyQvia
Status: COMPLETED
Conditions: Exposure During Pregnancy
Interventions: BIOLOGICAL: A licensed human normal immunoglobulin other than HYQVIA for IV or SC infusion or an alternative treatment|BIOLOGICAL: HYQVIA [Immune Globulin Infusion 10% (Human) with Recombinant Human Hyaluronidase]
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Development of A Technique to Predict Antidepressant Responsiveness in Depressive Patients
Status: UNKNOWN
Conditions: Depression|Continuous Antidepressant Abuse|Adverse Reaction to Drug
Interventions: DRUG: SSRI treated group
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Tests The Safety And Effectiveness Of SU011248 In Patients With Non-Small Cell Lung Cancer Having Brain Metastases
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: Sunitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Primary Prevention of Cardiovascular Disease (CVD) in Pre-diabetic & Pre-hypertensive Subjects
Status: UNKNOWN
Conditions: Pre-diabetes|Pre-hypertension
Interventions: DRUG: Metformin+Enalapril+Simvastatin|DRUG: Placebo tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Intensive Therapy for Children With Microcephaly, Hyperkinetic Movements, or Global Developmental Delay
Status: COMPLETED
Conditions: Microcephaly|Hyperkinesis With Developmental Delay|Global Developmental Delay
Interventions: BEHAVIORAL: Acquire Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing AT-101 in Combination With Docetaxel and Prednisone Versus Docetaxel and Prednisone in Men With Chemotherapy-Naïve Metastatic Hormone Refractory Prostate Cancer (HRPC)
Status: COMPLETED
Conditions: Hormone Refractory Prostate Cancer
Interventions: DRUG: AT-101, prednisone and docetaxel|DRUG: placebo, prednisone and docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics of Antiretroviral Drugs in Lactating Women and Breastmilk Fed Infants Under 6 Months of Age in Botswana
Status: RECRUITING
Conditions: Lactating Women on Select DOI|Breastmilk Fed Infants of Mothers on Select DOI|HIV Infections
Interventions: DRUG: Dolutegravir|DRUG: Lamivudine|DRUG: Emtricitabine|DRUG: Tenofovir Disoproxil Fumarate
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Camrelizumab Combined With SRT/WBRT and Chemotherapy in Patients With Brain Metastases of Driven Gene-negative NSCLC
Status: UNKNOWN
Conditions: Non-Small-Cell Lung Cancer
Interventions: DRUG: Camrelizumab|DRUG: Placebo|DRUG: Cisplatin|DRUG: Carboplatin|DRUG: Pemetrexed|DRUG: Paclitaxel|DRUG: Albumin paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hemodynamic Responses to Tracheal Intubation Direct Laryngoscope and Videolaryngoscope in Elderly Patients
Status: COMPLETED
Conditions: Aged Patients
Interventions: DEVICE: Macintosh Laryngoscope|DEVICE: McGRATH Videolaryngoscope
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Oral Ubrogepant to Assess Adverse Events and Change in Disease Activity in Adult Participants With Menstrual Migraine
Status: RECRUITING
Conditions: Migraine
Interventions: DRUG: Ubrogepant|DRUG: Placebo for Ubrogepant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial Evaluating the Safety and Effectiveness of the Laminar Left Atrial Appendage Closure System in Subjects With Non-Valvular Atrial Fibrillation
Status: RECRUITING
Conditions: Atrial Fibrillation
Interventions: DEVICE: Left Atrial Appendage Closure
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PENG and LFCN Block Versus Lumbar Plexus Block for Postoperative Analgesia After Total Hip Arthroplasty
Status: RECRUITING
Conditions: Post Operative Pain|Regional Block
Interventions: PROCEDURE: pericapsular nerve group and lateral femoral cutaneous nerve block|PROCEDURE: lumbar plexus block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Biomarker Study: Heart Failure Patients at Risk
Status: UNKNOWN
Conditions: Heart Failure NYHA Class II|Heart Failure NYHA Class III|Heart Failure NYHA Class IV
Interventions: DRUG: Angiotensin 1-7|DRUG: Saline solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT