pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Continuous Glucose Metrics in Patients With Gastroparesis in Type 1 or Type 2 Diabetes
Status: RECRUITING
Conditions: Diabetes Mellitus, Type 2|Diabetes Mellitus, Type 1|Gastroparesis With Diabetes Mellitus
Interventions: DEVICE: FreeStyle Libre 3 continuous glucose monitoring sensor|OTHER: Nutritional drink
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Phase I/II Study of MK-0752 Followed by Docetaxel in Advanced or Metastatic Breast Cancer
Status: COMPLETED
Conditions: Metastatic Breast Cancer
Interventions: DRUG: MK-0752, Docetaxel, Pegfilgrastim
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of Profound Muscle Relaxation on Muscle Trauma and Postoperative Pulmonary Function
Status: UNKNOWN
Conditions: Profound Muscle Relaxation|Muscle Trauma|Postoperative Analgesic Demand|Postoperative Pulmonary Function
Interventions: DRUG: profound neuromuscular blockade
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess Bioequivalence of a New Nifurtimox Oral Tablet Formulation
Status: COMPLETED
Conditions: Bioequivalence
Interventions: DRUG: Nifurtimox (Lampit, BAYA2502)_Test|DRUG: Nifurtimox (Lampit, BAYA2502)_Reference
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Randomized Trial of G-CSF Alone Versus Intermediate-dose Ara-C Plus G-CSF Mobilization in Hodgkin's Lymphoma or Non-Hodgkin's Lymphoma
Status: UNKNOWN
Conditions: Hodgkin's Lymphoma|Non-Hodgkin's Lymphoma
Interventions: DRUG: G-CSF (filgrastim)|DRUG: Cytosine arabinoside with G-CSF (filgrastim)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Darbepoetin Alfa in Patients With "Poor Prognosis" Germ Cell Tumor Treated With High-Dose Chemotherapy (HD-VIP)
Status: COMPLETED
Conditions: Dysgerminoma
Interventions: DRUG: Darbepoetin alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dexmedetomidine Combined With Lidocaine Infusion Affect Inflammation Cytokines
Status: COMPLETED
Conditions: Anesthesia; Reaction
Interventions: DRUG: Saline|DRUG: Lidocaine|DRUG: Dexmedetomidine|DRUG: Lidocaine plus Dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Resolution of Microalbuminuria and Dysmetabolism Following Bariatric Surgery: Prospective Study
Status: UNKNOWN
Conditions: Microalbuminuria|Gastrectomy|Biliopancreatic Diversion With Duodenal Switch
Interventions: PROCEDURE: Gastrectomy|PROCEDURE: BPD-DS
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Multi-Tracer Positron Emission Tomography in Patients With Solid Tumors
Status: TERMINATED
Conditions: Malignant Neoplasm
Interventions: RADIATION: [F-18]fluorodeoxyglucose|RADIATION: [F-18]fluorothymidine|PROCEDURE: Positron Emission Tomography|RADIATION: Water O-15
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Phase 1b/2a, Open-label Single Ascending Doses and Multiple Ascending Doses Study in Participants With Pi*ZZ AATD
Status: RECRUITING
Conditions: Alpha-1 Antitrypsin Deficiency
Interventions: DRUG: WVE-006
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study To Evaluate The Effect Of Food On The Behavior of Tofacitinib Modified Release 22 Milligram Tablets In Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Tofacitinib MR 22 mg (Fed)|DRUG: Tofacitinib MR 22 mg (Fasted)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: 3D Sonohysterography vs Hysteroscopy: Study for the Evaluation of Intrauterine Abnormalities
Status: UNKNOWN
Conditions: Uterine Diseases
Interventions: DEVICE: diagnostic hysteroscopy|DEVICE: diagnostic sonar test
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effects of Food Form on Cephalic Phase Responses
Status: COMPLETED
Conditions: Obese|Overweight
Interventions: BEHAVIORAL: Learned: Non-nutritive beverage to Non-nutritive beverage|BEHAVIORAL: Learned: Nutritive solid to Nutritive solid|BEHAVIORAL: Learned: Nutritive beverage to Nutritive beverage|BEHAVIORAL: Not Learned: Non-nutritive solid to Nutritive solid|BEHAVIORAL: Not Learned: Nutritive beverage to Non-nutritive beverage|BEHAVIORAL: Not Learned: Non-Nutritive solid to Non-nutritive solid|BEHAVIORAL: Not Learned: Non-nutritive beverage to Nutritive beverage|BEHAVIORAL: Not Learned: Non-Nutritive solid to Non-Nutritive Solid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of Fludarabine + Cyclophosphamide + TBI Conditioning Regimen for Double Units Cord Blood Transplantation(CBT)in Severe Aplastic Anemia(SAA)
Status: UNKNOWN
Conditions: Aplastic Anemia
Interventions: OTHER: Cyclophosphosphamide, TBI
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study With Primatrix Dermal Repair Scaffold For The Treatment Of Diabetic Foot Ulcers
Status: TERMINATED
Conditions: Foot Ulcer, Diabetic
Interventions: DEVICE: PriMatrix|OTHER: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Role of Mesh Stoma Reinforcement Technique (MSRT) in Prevention of Parastomal Hernia After Ileal Conduit Urinary Diversion
Status: UNKNOWN
Conditions: Ileal Conduit|Parastomal Hernia
Interventions: PROCEDURE: Polypropylene Mesh Stoma reinforcement technique with ileal conduit urinary diversion|PROCEDURE: Ileal conduit urinary diversion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Transepicardial With Transseptal Autologous CD 133+ Bone Marrow Cell Implantation in Patient Following CABG Surgery
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: BIOLOGICAL: Transepicardial with Transseptal CD 133+ Implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Visceral Function Following Endovascular Aortic Aneurysm Repair Using Branched Stent- Grafts
Status: ENROLLING_BY_INVITATION
Conditions: Aortic Aneurysm, Abdominal|Ascending Aorta Aneurysm|Aortic Arch Aneurysm
Interventions: DEVICE: Endovascular repair of thoracoabdominal aortic aneurysm (TAAA) using branched stent graft|DEVICE: Endovascular repair of ascending/arch aortic aneurysm using branched stent graft
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Comparative Analysis of Intra-articular Injection of Steroid and/or Sodium Hyaluronate in Adhesive Capsulitis
Status: COMPLETED
Conditions: Adhesive Capsulitis
Interventions: PROCEDURE: isotonic saline injection into the glenohumeral joint|PROCEDURE: steroid injection into the glenohumeral joint|PROCEDURE: sodium hyaluronate injection into the glenohumeral joint|PROCEDURE: steroid and hyaluronate injection into the glenohumeral joint
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Atorvastatin in the Treatment of Mandibular Degree II Furcation Defects
Status: COMPLETED
Conditions: Chronic Periodontitis
Interventions: DRUG: Atorvastatin (ATV)|DRUG: Placebo Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Mechanical Device During Acute Respiratory Failure in Patients With Neuromuscular Disorders
Status: TERMINATED
Conditions: Duchenne Muscular Dystrophy|Amyotrophic Lateral Sclerosis|Neuromuscular Diseases
Interventions: DEVICE: mechanical insufflation - exsufflation|DEVICE: Standard respiratory physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Safety of Substituting Exenatide for Insulin in Patients Using Insulin and Oral Antidiabetic Agents
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: exenatide|DRUG: Insulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating 2 Dosing Regimens Of TRU-015 In Rheumatoid Arthritis
Status: TERMINATED
Conditions: Arthritis, Rheumatoid
Interventions: DRUG: TRU-015|DRUG: Methylprednisolone|DRUG: Prednisone|DRUG: TRU-015|DRUG: Methylprednisolone|DRUG: Prednisone|DRUG: TRU-015|DRUG: Methylprednisolone|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficiency of Speech Therapy in Resistant Hypertensive Patients With Mild Obstructive Sleep Apnea Syndrome
Status: UNKNOWN
Conditions: Sleep Apnea, Obstructive|Hypertension Secondary
Interventions: OTHER: Speech therapy|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Palonosetron and Ramosetron for Preventing Patient-controlled Analgesia Related Nausea and Vomiting Following Spine Surgery
Status: COMPLETED
Conditions: Postoperative Nausea and Vomiting
Interventions: DRUG: ramosetron|DRUG: palonosetron
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: JeffQuit Group Therapy Program for Smoking Cessation in Patients With a History of Cancer
Status: WITHDRAWN
Conditions: Current Smoker|Malignant Neoplasm
Interventions: OTHER: Tobacco Cessation Counseling|OTHER: Support Group Therapy|OTHER: Quality-of-Life Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparison of Meal Replacements Versus Protein Supplements and Utilizing the Protein Digestibility Corrected Amino Acid Score (PDCAAS) Method
Status: UNKNOWN
Conditions: Protein Deficiency
Interventions: DIETARY_SUPPLEMENT: Group 1 Meal Replacement|DIETARY_SUPPLEMENT: Group 2 Protein Supplement|DIETARY_SUPPLEMENT: Group 3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SCREENING
Clinical trial: Using the EHR to Advance Genomic Medicine Across a Diverse Health System
Status: RECRUITING
Conditions: Genetic Predisposition|Paraganglioma|Pheochromocytoma|ALS|Parkinson Disease|Polyneuropathies|Frontotemporal Dementia|Alzheimer Disease|Cardiomyopathy Non-ischemic|Thoracic Aortic Aneurysm
Interventions: BEHAVIORAL: Behavioral nudge
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: PDT and Periodontal Treatment in DMT2 Patients
Status: COMPLETED
Conditions: Periodontitis|Diabetes Mellitus Type 2
Interventions: PROCEDURE: Periodontal treatment|PROCEDURE: Periodontal treatment and PDT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Tolerability of Atomoxetine (Strattera) in Adult Patients With Generalized Social Anxiety Disorder
Status: COMPLETED
Conditions: Generalized Social Phobia
Interventions: DRUG: atomoxetine|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Evaluate the Anti-adhesion Efficacy and Safety of MegaShield®-SP in Comparison With Guardix-SP Plus After Spine Surgery
Status: RECRUITING
Conditions: Herniation, Disc
Interventions: DEVICE: MegaShield®-SP|DEVICE: Guardix-SP Plus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Meal Timing on Postprandial Glucose, Insulin and GLP-1 in Type 2 Diabetes
Status: UNKNOWN
Conditions: Type 2 Diabetes
Interventions: OTHER: High Calorie Breakfast (BTdiet)|OTHER: High Caloric Dinner (DTdiet)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Non-Alcoholic Steatohepatitis (NASH) on the Pharmacokinetics of 99mTechnetium-Mebrofenin
Status: COMPLETED
Conditions: Non-alcoholic Steatohepatitis
Interventions: DRUG: Technetium Tc 99M Mebrofenin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: PRO-122 Versus Concomitant Therapy in Subjects With Uncontrolled Primary Open-angle Glaucoma (PRO-122LATAM)
Status: RECRUITING
Conditions: Primary Open-angle Glaucoma
Interventions: DRUG: PRO-122|DRUG: Timolol eye drops|DRUG: Dorzolamide-Timolol Ophthalmic|DRUG: Brimonidine Ophthalmic Solution|OTHER: Placebo1|OTHER: Placebo 2|DRUG: Krytantek
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Dexmedetomidine and Propofol on Cerebral Blood Flow and Brain Oxygenation During Deep Brain Stimulation
Status: COMPLETED
Conditions: Intracranial Neurosurgery
Interventions: DRUG: dexmedetomidine|DRUG: propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: The Efavirenz (EFV) Central Nervous System Exposure Sub-study of Encore1
Status: COMPLETED
Conditions: HIV Infection
Interventions: DRUG: Efavirenz|DRUG: Efavirenz
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: MD2Me - Texting to Promote Chronic Disease Management
Status: COMPLETED
Conditions: Cystic Fibrosis|Inflammatory Bowel Disease|Type 1 Diabetes|Chronic Disease Management
Interventions: BEHAVIORAL: MD2ME
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Mobile Integrated Healthcare and Community Paramedicine
Status: UNKNOWN
Conditions: Hospital Readmission|Pneumonia|Myocardial Infarction|COPD
Interventions: OTHER: Mobile Integrated Healthcare/Community Paramedicine (MIH/CP) Support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Combination Chemotherapy, Total-Body Irradiation, Peripheral Stem Cell Transplantation, and Lymphocyte Infusion in Treating Patients With Stage IV Melanoma
Status: COMPLETED
Conditions: Melanoma (Skin)
Interventions: BIOLOGICAL: therapeutic allogeneic lymphocytes|DRUG: cyclosporine|DRUG: fludarabine phosphate|DRUG: mycophenolate mofetil|PROCEDURE: peripheral blood stem cell transplantation|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Photobiomodulation Therapy (PBMT) and a Cold-Water Immersion (CWI) in Recovery Soccer Player: Analysis of Biochemical Markers of Recovery and Muscular Oxidative Stress.
Status: COMPLETED
Conditions: Soccer|Fatigue|Oxidative Stress|Recovery|Cold Water Immersion|Photobiomodulation Therapy
Interventions: OTHER: Photobiomodulation Therapy|OTHER: Cold Water Immersion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Olux E Foam and Sorilux Foam Combination Therapy for the Maintenance of Treatment Response in Patients With Moderate Plaque Psoriasis
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: vehicle foam|DRUG: calcipotriene|DRUG: calcipotriene + clobetasol propionate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Controlled Trial With Deep Brain Stimulation in Patients With Early Parkinson's Disease
Status: UNKNOWN
Conditions: Parkinson Disease
Interventions: DEVICE: Kinetra and Soletra (neurostimulator, Medtronic)|DRUG: Best Medical Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A First-in-human Study of the Safety, Tolerability, and PK of XFB-19 in Healthy Adult Volunteers
Status: UNKNOWN
Conditions: Idiopathic Pulmonary Fibrosis (IPF)
Interventions: DRUG: XFB-19|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of a Homecare Dentin Hypersensitivity Gel
Status: COMPLETED
Conditions: Dentin Sensitivity
Interventions: DRUG: placebo gel|DRUG: 5% sodium fluoride, potassium oxalate 5%, strontium chloride 10%|DRUG: Fluoride neutral NaF gel 2 %
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Vyvanse and Adderall XR Given Alone and in Combination With Prilosec OTC
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Lisdexamfetamine Dimesylate|DRUG: Adderall XR (mixed salts amphetamine)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Flexion Versus Extension Soft Tissue Repair in Total Knee Arthroplasty
Status: COMPLETED
Conditions: Total Knee Arthroplasty(TKA)|Total Knee Replacement
Interventions: PROCEDURE: soft tissue repair in flexion position|PROCEDURE: soft tissue repair in extension position
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose:
Clinical trial: Study on the Safety and Efficacy of Dalbavancin Versus Active Comparator in Adult Participants With Osteomyelitis
Status: COMPLETED
Conditions: Osteomyelitis
Interventions: DRUG: Dalbavancin|DRUG: Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability of WVE-120101 in Patients With Huntington's Disease
Status: TERMINATED
Conditions: Huntington's Disease
Interventions: DRUG: WVE-120101|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dual Therapy With Boosted Darunavir + Dolutegravir
Status: COMPLETED
Conditions: HIV-Infection
Interventions: DRUG: Prezista|DRUG: Norvir|DRUG: Tivicay|DRUG: Truvada|DRUG: Kivexa|DRUG: Descovy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of MabThera (Rituximab) in Patients With Rheumatoid Arthritis Who Have Had an Inadequate Response to a Single Anti-TNF Inhibitor.
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Methotrexate|DRUG: rituximab [MabThera/Rituxan]
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sleep to Reduce Incident Depression Effectively in Peripartum
Status: NOT_YET_RECRUITING
Conditions: Insomnia|Depression
Interventions: BEHAVIORAL: Perinatal Understanding of Mindful Awareness for Sleep (PUMAS)|OTHER: Treatment-as-usual (TAU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pragmatic Posterior Capsular Stretch Versus Sleeper Stretch in Subject With Shoulder Pathologies
Status: UNKNOWN
Conditions: Shoulder Impingement|Shoulder Arthritis|Shoulder Injuries|Shoulder Capsulitis|Shoulder Bursitis|Shoulder Pain Chronic
Interventions: OTHER: Pragmatic Set of intervention and posterior capsular stretch|OTHER: Pragmatic Set of intervention and Sleeper Stretch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Feasibility of Polychromatic Light Emitting Diode for Peripheral Catheter Illumination During Peripheral Intravenous Delivery of Normal Saline
Status: COMPLETED
Conditions: Quality of Life|Fatigue
Interventions: DEVICE: UVL1000 Treatment Station|DRUG: Normal Saline Solution|DEVICE: Peripheral Catheterization
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Product Transference Study of Testagen™ TDS®-Testosterone
Status: ENROLLING_BY_INVITATION
Conditions: Hypogonadotropism
Interventions: DRUG: Testagen® TDS Testosterone 5% HypoSpray®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Canadian Active & Maintenance Modified Pentasa Study
Status: COMPLETED
Conditions: Active Ulcerative Colitis|Remission of Ulcerative Colitis
Interventions: DRUG: 5-ASA (5-Aminosalicylate)|DRUG: 5-ASA (5-Aminosalicylate)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Four Different Regimens of Adapalene 0.1% / Benzoyl Peroxide 2.5% Gel in Acne Vulgaris
Status: COMPLETED
Conditions: Acne
Interventions: DRUG: Adapalene BPO Gel standard daily overnight application|DRUG: Adapalene-BPO 3-hour daily application before bedtime|DRUG: Adapalene-BPO Gel every other day application|DRUG: Adapalene-BPO Gel standard+Cetaphil® Moisturizing Lotion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Remodulin® in Pediatric Pulmonary Hypertension With Single Ventricular Physiology After Fontan Surgery
Status: COMPLETED
Conditions: Pulmonary Hypertension
Interventions: DRUG: Remodulin|DRUG: distilled water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Drug-Drug Interaction Study of Vadadustat With Rosuvastatin, Sulfasalazine, Pravastatin, Atorvastatin and Simvastatin
Status: COMPLETED
Conditions: Drug Interaction Potentiation
Interventions: DRUG: Vadadustat|DRUG: Simvastatin|DRUG: Rosuvastatin|DRUG: Atorvastatin|DRUG: Pravastatin|DRUG: Sulfasalazine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Dexmedetomidine for Cesarean Delivery
Status: COMPLETED
Conditions: Pregnant Women Undergoing Cesarean Delivery
Interventions: DRUG: Dexmedetomidine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Topical and Local TXA in Facelifts - A Randomized Controlled Double Blinded Study
Status: RECRUITING
Conditions: Hemophilia|Hemorrhage|Facelift Surgery
Interventions: DRUG: 1%Tranexamic acid with standard local|DRUG: 3% TXA|DRUG: 1% TXA with local plus 3% TXA-soaked pledgets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Adjunctive Use Of A Novel Hyaluronic Acid/Chlorhexidine Gel In The Non Surgical Treatment Of Periodontitis
Status: RECRUITING
Conditions: Periodontitis|Hyaluronic Acid|Chlorhexidine
Interventions: PROCEDURE: Non surgical periodontal therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: The FAST OCT Study
Status: UNKNOWN
Conditions: Tomography, Optical Coherence|Myocardial Revascularization|NSTEMI - Non-ST Segment Elevation MI|Unstable Angina|Coronary Arteriosclerosis|3D-angio-based FFR
Interventions: DIAGNOSTIC_TEST: Optical coherence tomography assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: New Hydroxyethyl Cellulose Hydrogel for the Treatment of the Pain of Knee Arthrosis
Status: ACTIVE_NOT_RECRUITING
Conditions: Osteoarthritis, Knee|Pain
Interventions: DEVICE: Hydrogel injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Lumbar Plexus Block Success With Near Infrared Spectroscopy (NIRS)
Status: NOT_YET_RECRUITING
Conditions: Nerve Block|Lumbar Plexus|Near Infrared Spectroscopy
Interventions: DEVICE: Near Infrared Spectroscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: 12-week Safety Evaluation of Oral CS-0777 in Multiple Sclerosis Patients
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DRUG: CS-0777 tablets|DRUG: CS-0777 tablets|DRUG: CS-0777 tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Image Guided IMRT, Radiochemotherapy and MRI-based IGABT in Locally Advanced Cervical Cancer
Status: RECRUITING
Conditions: Uterine Cervical Neoplasms
Interventions: RADIATION: Increased use of IC/IS technique in BT|RADIATION: Reduction of vaginal source loading|RADIATION: Systematic utilisation of IMRT|RADIATION: Utilisation of daily IGRT (set-up according to bony structures)|RADIATION: EBRT target concept related to the primary tumor (CTV-T) and internal motion; concepts for OAR contouring|RADIATION: EBRT dose prescription and reporting|RADIATION: Adaptation of EBRT nodal elective CTV according to risk of nodal and systemic recurrence|DRUG: Systemic application of simultaneous chemotherapy|OTHER: Reduction of overall treatment time
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Acupuncture for Major Trauma
Status: UNKNOWN
Conditions: Major Trauma
Interventions: PROCEDURE: Electroacupuncture (EA)|PROCEDURE: Laser acupuncture (LA)|PROCEDURE: Sham laser acupuncture (SLA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multi-Center Study of New Medications to Treat Vaginal Infections
Status: COMPLETED
Conditions: Vaginal Infection
Interventions: DRUG: Metronidazole|DRUG: Gel vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: THRIVE BY 3 Daycare to Promote Development/ Mental Health in 1&2 Year-olds
Status: COMPLETED
Conditions: Childcare Quality|Child Development
Interventions: BEHAVIORAL: Thrive by Three|BEHAVIORAL: Treatment as usual (TAU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Typhoid Vi Vaccine Effectiveness in Hechi, Guangxi, China
Status: COMPLETED
Conditions: Typhoid|Paratyphoid Fever
Interventions: BIOLOGICAL: Typhoid Vi vaccine|BIOLOGICAL: Meningococcal A (control)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Prasugrel vs. Ticagrelor on Myocardial Injury in STEMI
Status: COMPLETED
Conditions: ST Elevation Myocardial Infarction
Interventions: DRUG: Prasugrel|DRUG: Ticagrelor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose-ranging Study for Postoperative Analgesia in Subjects Undergoing Primary Unilateral Inguinal Hernia Repair
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: Bupivacaine HCl|DRUG: SKY0402
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Influence of EPICardial Adipose Tissue in HEART Diseases: EPICHEART Study
Status: UNKNOWN
Conditions: Coronary Artery Disease|Coronary Arteriosclerosis|Atrial Fibrillation|Left Atrial Abnormality|Severe Aortic Stenosis
Interventions: OTHER: Aortic valve replacement
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Clinical Study of the GO-LIF® Approach for Lumbar Spinal Fixation
Status: COMPLETED
Conditions: Lower Back Pain
Interventions: PROCEDURE: GO-LIF - Guided Oblique Lumbar Interbody Fusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Proof-of-concept Study With NVDX3 for Treatment of Distal Radius Fractures.
Status: ACTIVE_NOT_RECRUITING
Conditions: Distal Radius Fractures
Interventions: DRUG: NVDX3
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating "Health at Every Size"(HAES) as an Alternative Obesity Treatment Model
Status: COMPLETED
Conditions: Hypercholesterolemia|Hypertension|Depression|Diabetes Mellitus, Type 2
Interventions: BEHAVIORAL: Health at Every Size (HAES)|BEHAVIORAL: Diet (Traditional, moderate energy restriction)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: AV Node Isolation in Atrial Fibrillation vs. Modulation by "Pace and Ablate" Strategy
Status: COMPLETED
Conditions: Atrial Fibrillation|AV Node Ablation|Escape; Rhythm
Interventions: PROCEDURE: AV-node isolation|PROCEDURE: AV-node ablation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Developing Risk Prediction Model and Testing the Effect of Dual Task Walking on Improving Cognitive Function in Patients With Colorectal Cancer
Status: UNKNOWN
Conditions: Colorectal Cancer
Interventions: BEHAVIORAL: dual-task walking
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Trial Using Motivational Interviewing Positive Affect and Self-Affirmation in Hypertension (TRIUMPH)
Status: COMPLETED
Conditions: Hypertension
Interventions: BEHAVIORAL: Positive Affect/Self-Affirmation/Motivational Interviewing|BEHAVIORAL: Educational and Behavioral
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Endorphin Massage Applied to Postpartum Women on Anxiety and Fatigue Levels
Status: COMPLETED
Conditions: Birth|Anxiety|Fatigue
Interventions: OTHER: massage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Etanercept and Celecoxib Alone/Combined Treatment in Effectiveness and Safety of Active Ankylosing Spondylitis
Status: COMPLETED
Conditions: Ankylosing Spondylitis
Interventions: DRUG: celebrex|DRUG: Enbrel|DRUG: Enbrel plus Celebrex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aerobic Training in Metastatic Breast Cancer
Status: COMPLETED
Conditions: Metastatic Breast Cancer
Interventions: BEHAVIORAL: Progressive Stretching Group|BEHAVIORAL: Nonlinear Aerobic Training|OTHER: Blood draw|OTHER: Cardiopulmonary Exercise Testing (CPET)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Clinical Efficacy and Safety Study of Insulin Glargine U300 in Chinese Adult Patients With Uncontrolled Type 2 Diabetes Mellitus With a 3-month Extension Period
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Insulin glargine 300 U/ml
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Real World, Observational Registry of Chronic Wounds and Ulcers
Status: RECRUITING
Conditions: Diabetic Foot|Varicose Ulcer|Pressure Ulcer|Surgical Wound Dehiscence|Vasculitis|Skin Ulcer|Leg Ulcer|Wounds and Injuries|Pyoderma|Peripheral Arterial Disease|Diabetic Neuropathies|Lymphedema|Venous Insufficiency|Diabetes Complications|Amputation Stump
Interventions: OTHER: Usual care
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: "CAP" Fetge Gras. Lifestyle Modification Program in Catalonia.
Status: COMPLETED
Conditions: Non-Alcoholic Fatty Liver Disease|Liver Diseases|Lifestyle, Healthy
Interventions: BEHAVIORAL: Intervention CFG App|BEHAVIORAL: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of 800mg of Rhodiola Rosea in Attention in Adults With Attention-Deficit/Hyperactivity Disorder
Status: UNKNOWN
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: DRUG: Rhodiola|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Exenatide-test for Diagnosing Endogenous Hyperinsulinemic Hypoglycemia
Status: COMPLETED
Conditions: Endogenous Hyperinsulinism
Interventions: DRUG: Exenatide|DRUG: 0.9% saline solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Ketamine as an Anaesthetic Agent in Electroconvulsive Therapy (ECT)
Status: COMPLETED
Conditions: Major Depressive Episode
Interventions: DRUG: Ketamine|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Examine the Effect of Omeprazole, Famotidine, and an Acidic Beverage on the Pharmacokinetics of Entinostat in Healthy Adult Subjects
Status: COMPLETED
Conditions: Volunteers|Healthy Volunteers|Human Volunteers|Normal Volunteers
Interventions: DRUG: entinostat|DIETARY_SUPPLEMENT: Omeprazole|DIETARY_SUPPLEMENT: Famotidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study of Istradefylline (KW-6002) as Monotherapy in Parkinson's Disease (PD) Patients
Status: COMPLETED
Conditions: Parkinson's Disease|Movement Disorder Syndrome
Interventions: DRUG: Istradefylline (KW-6002)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Trial to Evaluate Pharmacokinetics, Immunogenicity, Safety, and Tolerability of LEO 138559 in Healthy Japanese Subjects
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: LEO 138559|DRUG: LEO 138559 Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Analgesia for Positioning Hip Fracture Patients for Spinal Anesthesia
Status: COMPLETED
Conditions: Hip Fracture
Interventions: DRUG: Fentanyl|PROCEDURE: Fascia iliaca compartment block|DRUG: ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Preoperative Radiotherapy in Patients at High Risk of Postoperative Pancreatic Fistula After Pancreatoduodenectomy
Status: RECRUITING
Conditions: Neuroendocrine Carcinoma of Pancreas|Duodenum Carcinoma|Pancreas Neoplasm|Distal Cholangiocarcinoma|GIST|Pancreas Fibrosis|Pancreatic Fistula
Interventions: RADIATION: Stereotactic radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Non-Steroidal or Opioid Analgesia Use for Children With Musculoskeletal Injuries
Status: COMPLETED
Conditions: Musculoskeletal Injury
Interventions: DRUG: Ibuprofen|DRUG: Acetaminophen|DRUG: Hydromorphone|DRUG: Acetaminophen placebo|DRUG: Hydromorphone placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cholecystitis From a Microbiological and Histopathological Perspective
Status: RECRUITING
Conditions: Calculous Cholecystitis|Antibiotic Resistant Infection|Gallbladder Inflammation
Interventions: OTHER: Microbiological and histopathological investigation of bile and gallbladder wall specimens.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Early Airway Response to Allergen in Asthmatics (MK-0000-176)
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Nedocromil|DRUG: Comparator: Montelukast|DRUG: Comparator: Mometasone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Transcranial Electrical Stimulation in Subacromial Pain Syndrome
Status: RECRUITING
Conditions: Subacromial Pain Syndrome
Interventions: OTHER: Strenghtening + TES
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Preliminary Testing of the Vitaliti CVSM Wearable, Vitaliti Spirotoscope, and Vitaliti IVD Station
Status: COMPLETED
Conditions: Urinary Tract Infection|Diabetes Mellitus|Atrial Fibrillation|OSA|COPD|Pneumonia|Acute Otitis Media|Leukocytosis|Iron Deficient Anemia|Hypertension|Healthy Volunteers
Interventions: DEVICE: Vitaliti
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Prevalence of Distal Radial Artery Occlusion in Cardiovascular Catheterization Via Distal Radial Access
Status: COMPLETED
Conditions: Catheterization|Complications|Distal Radial Artery
Interventions: PROCEDURE: cardiac catheterization via distal radial artery
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy of Desonide (Desonatetm) Gel 0.05% in Younger and Older Subjects With Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: topical desonide hydrogel 0.05%
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Steroid Sparing Potential Study of DGLA Cream in Early Childhood Patients With Moderate to Severe Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: DS107E|DRUG: Vehicle|DRUG: Hydrocortisone Butyrate 0.1% Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Adjunctive Benefit of Xenograft Plus a Membrane During Sinus Crestal Approach
Status: UNKNOWN
Conditions: Edentulous Jaw
Interventions: PROCEDURE: Transcrestal approach for sinus lift|PROCEDURE: Xenograft application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Minimally Invasive Robotic Surgery, Role in Optimal Debulking Ovarian Cancer, Recovery & Survival
Status: UNKNOWN
Conditions: Ovarian Cancer|Ovarian Neoplasm|Ovarian Neoplasm Epithelial|Fallopian Tube Cancer|Peritoneal Cancer
Interventions: PROCEDURE: Robotic Interval Debulking Surgery
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Biomarkers in Tissue Samples From Patients With Recurrent or Metastatic Head and Neck Cancer Treated on ECOG-E1395 and ECOG-E3301
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: GENETIC: gene expression analysis|GENETIC: in situ hybridization|OTHER: immunohistochemistry staining method|OTHER: laboratory biomarker analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of ET140202 T Cells in Adults With Advanced Hepatocellular Carcinoma
Status: TERMINATED
Conditions: Hepatocellular Carcinoma|Liver Cancer|Liver Neoplasm|Metastatic Liver Cancer
Interventions: BIOLOGICAL: ET140202 autologous T cell product
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Psychological Effects of Methylenedioxymethamphetamine (MDMA) When Administered to Healthy Volunteers (MT-2)
Status: WITHDRAWN
Conditions: Psychological Effects of Study Drug
Interventions: DRUG: Midomafetamine|BEHAVIORAL: Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect of Nebivolol in Hypertensive Patients With Coronary Arterial Spasm
Status: COMPLETED
Conditions: Coronary Vasospasm
Interventions: DRUG: Nebivolol|DRUG: Diltiazem|DRUG: Nebivolol+Diltiazem
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of NG-350A Plus Pembrolizumab in Metastatic or Advanced Epithelial Tumours (FORTIFY)
Status: ACTIVE_NOT_RECRUITING
Conditions: Epithelial Tumor|Metastatic Cancer
Interventions: BIOLOGICAL: NG-350A plus Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PNF in Subacromial Impingement Syndrome
Status: COMPLETED
Conditions: Subacromial Impingement Syndrome
Interventions: OTHER: Conventional therapy|OTHER: CT+ PNF in extremity pattern|OTHER: CT+ PNF in extremity pattern+PNF in scapula and upper trunk patterns
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Comparing Impacts of Donor Human Milk to Formula Supplementation on the Gut Microbiome of Full-term Infants
Status: RECRUITING
Conditions: Microbial Colonization
Interventions: OTHER: Donor Human Milk - Nutritional Replacement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Colistin Intravenous Administration in Critically Ill Patients Suffering From Hospital Infections Caused by Multi-antibiotic-resistant Germs.
Status: UNKNOWN
Conditions: Hospital Infection|Multi-antibiotic Resistance|Critically Ill
Interventions: DRUG: Colistin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Single-Group Clinical Trial Investigating the Effects of a Hair Vitamin Combination on Hair Growth and Hair Health
Status: COMPLETED
Conditions: Hair Health|Hair Loss
Interventions: DIETARY_SUPPLEMENT: Hair Nutra Growth Supplement & Hair Nutra Boost Supplement|DIETARY_SUPPLEMENT: Hair Nutra Growth
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Colorectal Cancer Screening in Familiar-Risk Population: Immunochemical Fecal Occult Blood Testing Versus Colonoscopy
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: PROCEDURE: Immunochemical fecal occult blood test And colonoscopy if test is positive|PROCEDURE: Colonoscopy with sedation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study on the Efficacy and Safety of a Device for Post-op Recovery in Pediatric Adenectomy/Adenotonsillectomy.
Status: NOT_YET_RECRUITING
Conditions: Adenoidal Disorder|Tonsillitis|Otorhinolaryngologic Diseases|Nasal Disease
Interventions: DEVICE: Munatoril Aerosol Combo|DEVICE: Iperclenny
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Higher Irradiance in Keratoconus Ectasia
Status: WITHDRAWN
Conditions: Keratoconus|Ectasia
Interventions: DEVICE: UVA Light with irradiance exposure of 9 mW/cm2|DRUG: Riboflavin 0.1% ophthalmic solution
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study on the Level of Neuromuscular Blockade
Status: COMPLETED
Conditions: Neuromuscular Blockade
Interventions: DRUG: A continuous intravenous infusion of 0.5-0.6 mg/kg/h Rocuronium Bromide Intravenous Solution (50 Mg/5 mL) to keep the target neuromuscular blockade (PTC = 1-2).|DRUG: A continuous intravenous infusion of 0.2-0.3 mg/kg/h Rocuronium Bromide Intravenous Solution (50 Mg/5 mL) to keep the target neuromuscular blockade (TOF = 1-2).
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT