pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: LISA-study : Levothyroxin in Nodular Goiter
Status: COMPLETED
Conditions: Goiter, Nodular
Interventions: DRUG: Levothyroxin-Na|DRUG: Levothyroxine-Na + iodide|DRUG: Iodide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: White Cover and Massage Impact on Bilirubin Levels and Phototherapy Duration in Newborns
Status: COMPLETED
Conditions: Newborn Jaundice|Hyperbilirubinemia, Neonatal|Newborn Massage|Phototerapy|White Cover
Interventions: OTHER: White cover
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Transverse Maxillary Expansion With a Segmental Le Fort I Osteotomy or Surgically Assisted Rapid Maxillary Expansion (SARME)
Status: RECRUITING
Conditions: Maxilla; Hypoplasia
Interventions: DEVICE: Bone borne distractor|DEVICE: Tooth borne distractor|PROCEDURE: Segmental LF1 Osteotomy group 1|PROCEDURE: Segmental LF1 Osteotomy group 2|PROCEDURE: Segmental LF1 Osteotomy group 3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Safety, Biodistibution and Sensitivity/Specificity of PET/CT Imaging With 89Zr-TLX250 in Subjects With RCC
Status: COMPLETED
Conditions: Carcinoma, Renal Cell|Clear Cell Renal Cell Carcinoma
Interventions: DIAGNOSTIC_TEST: 89Zr-girentuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Efficacy of an Ocular Bandage Contact Lens for the Treatment of Dry Eye After Complicated and Combined Cataract Surgery
Status: UNKNOWN
Conditions: Cataract|Lens Subluxation|Hypermature Cataract|Corneal Opacity|Small Pupil
Interventions: DEVICE: bandage contact lenses(PureVision; Bausch & Lomb Inc., Rochester, NY)|PROCEDURE: phacoemulsification
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Inflammation and Airway Changes That Occur After Exposure to Allergen in Asthmatics
Status: COMPLETED
Conditions: Asthma
Interventions: BIOLOGICAL: Segmental airway allergen challenge|PROCEDURE: Bronchoscopy|DIAGNOSTIC_TEST: Methacholine challenge test|DIAGNOSTIC_TEST: Spirometry|DIAGNOSTIC_TEST: Allergen skin prick test
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Correlation Between Oral Health and Systemic Inflammation (COHESION)
Status: COMPLETED
Conditions: Inflammation|Periodontal Disease|Gingivitis
Interventions: OTHER: Plaque disclosing toothpaste|OTHER: Non-plaque disclosing toothpaste
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Effectiveness of Vaccine Chatbot on HPV Vaccine Awareness and Vaccination in China
Status: RECRUITING
Conditions: HPV Vaccine
Interventions: OTHER: Vaccine chatbot that offering HPV vaccine-related information
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Effect of the SBS Decompression Technique on Gastrointestinal Symptoms During the Menstrual Cycle
Status: NOT_YET_RECRUITING
Conditions: Healthy
Interventions: OTHER: SBS Decompression Technique|OTHER: Placebo Technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Effect of Preoperative Oral Carbohydrates on the Insulin Resistance of Elderly Patients
Status: COMPLETED
Conditions: Old Age
Interventions: DIETARY_SUPPLEMENT: carbohydrate group - carbohydrate (400ml)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Adebrelimab and Chemoradiotherapy in High-risk Locoregionally Advanced Nasopharyngeal Carcinoma
Status: NOT_YET_RECRUITING
Conditions: Nasopharyngeal Carcinoma|Nasopharyngeal Cancer
Interventions: DRUG: Adebrelimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Observational Real-world Study Evaluating Severe Tricuspid Regurgitation Patients Treated With the Abbott TriClip™ Device (bRIGHT)
Status: ACTIVE_NOT_RECRUITING
Conditions: Tricuspid Valve Regurgitation
Interventions: DEVICE: Transcatheter heart valve procedure
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Biomarker Modulation by Inhibition of EGFR and/or SRC Family
Status: COMPLETED
Conditions: Head and Neck Cancer|Non Small Cell Lung Cancer
Interventions: DRUG: Erlotinib|DRUG: Dasatinib + Placebo|DRUG: Erlotinib plus Dasatinib|DRUG: Placebo|DRUG: Erlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bioprosthetic or Native Aortic Scallop Intentional Laceration to Prevent Iatrogenic Coronary Artery Obstruction (BASILICA) Prospective Investigation
Status: COMPLETED
Conditions: Native and Valve in Valve Aortic Valve Failure
Interventions: DEVICE: ASHI_INTECC Astato XS 20 0.014 guidewire
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Basilar Artery Occlusion Chinese Endovascular Trial
Status: COMPLETED
Conditions: Basilar Artery Occlusion|Ischemic Stroke|Cerebrovascular Disorders
Interventions: PROCEDURE: Mechanical embolectomy|DRUG: Medical Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Efficacy and Safety Proof of Concept Study of Daratumumab in Relapsed/Refractory Mantle Cell Lymphoma, Diffuse Large B-Cell Lymphoma, and Follicular Lymphoma
Status: TERMINATED
Conditions: Lymphoma, Mantle-Cell|Lymphoma, Large B-Cell, Diffuse|Lymphoma, Follicular
Interventions: DRUG: Daratumumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Proton Beam Therapy (PBT) Versus Intensity-Modulated Radiation Therapy (IMRT) Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Esophageal Cancer
Interventions: RADIATION: Proton Beam Therapy (PBT)|RADIATION: Intensity Modulated Radiation Therapy (IMRT)|BEHAVIORAL: Questionnaires
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improved Effects of MI Plus Alpha-LA in PCOS
Status: COMPLETED
Conditions: Polycystic Ovary Syndrome
Interventions: DIETARY_SUPPLEMENT: myo-inositol plus folic acid|DIETARY_SUPPLEMENT: myo-inositol plus folic acid plus alpha-lactalbumin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TMC278-TiDP15-C158 - A Study to Examine the Safety, Tolerability and Pharmacokinetics of a Single Dose or Three Successive Doses of Intramuscularly (IM) Injected Long Acting Formulation of TMC278
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: TMC278 (Rilpivirine) LA; Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Prospective Observational Study to Validate Circulating HPVDNA and Prognostic Genomic Biomarkers in HPV-associated OPSCC
Status: RECRUITING
Conditions: Oropharyngeal Squamous Cell Carcinoma|Carcinoma, Squamous Cell|Head and Neck Squamous Cell Carcinoma|Oropharynx Squamous Cell Carcinoma
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: This is a Post Approval Study of Coaptite® in the Treatment of Female Urinary Incontinence
Status: COMPLETED
Conditions: Female Stress Urinary Incontinence Due to Intrinsic Sphincter Deficiency
Interventions: DEVICE: Coaptite®
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Local Anesthetic at Incision Site
Status: UNKNOWN
Conditions: Post Operative Pain|Appendicitis
Interventions: DRUG: Pre Incisional Local Anesthetic|OTHER: Pre-Incisional Saline|DRUG: Post-Closure Local Anesthetic|OTHER: Post-Closure Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Optimizing Local Anesthetic Concentration for Continuous Popliteal-Sciatic Nerve Blocks
Status: COMPLETED
Conditions: Relatively Healthy Volunteers
Interventions: DRUG: Ropivacaine 0.1%|DRUG: Ropivacaine 0.4%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nicotine Administration and Post-operative Opioid Use With Bariatric Surgery
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: DRUG: Nasal Nicotine Spray|DRUG: Nasal Normal Saline Spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Reduction of Metabolic Acidosis in Patients With Chronic Kidney Disease in Stage 4 and 5
Status: RECRUITING
Conditions: Kidney Diseases|Metabolic Acidosis|Renal Insufficiency|CKD|Pre-dialysis
Interventions: OTHER: Low PRAL
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Inorganic Nitrate Supplement on Blood Pressure
Status: COMPLETED
Conditions: Blood Pressure|Endothelial Dysfunction
Interventions: DIETARY_SUPPLEMENT: Plant based bioequivalent Nitrate supplementation|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Project MARS: Mobile-Assistance for Regulating Smoking
Status: RECRUITING
Conditions: Current Smoker|Tobacco Smoking
Interventions: BEHAVIORAL: Messages (participants experiencing negative affect & cigarettes are available)|BEHAVIORAL: Messages (participants not experiencing negative affect & cigarettes are available)|BEHAVIORAL: Messages (participants experiencing negative affect & cigarettes are not available)|BEHAVIORAL: Messages (participants not experiencing negative affect & cigarettes are not available)|BEHAVIORAL: Moodsurf|BEHAVIORAL: Meditate|BEHAVIORAL: Joy|BEHAVIORAL: Imagine|BEHAVIORAL: Notice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Additive Anti-inflammatory Action for Aortopathy & Arteriopathy (Ulinastatin) II
Status: COMPLETED
Conditions: Acute Aortic Syndrome|Type A Aortic Dissection
Interventions: DRUG: Ulinastatin|DRUG: Blank control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acute Maternal and Fetal Effects of Exercise in Pregnancy
Status: COMPLETED
Conditions: Blood Pressure|Heart Rate and Rhythm Disorders|Hypoglycemia|Lactate|Nitrate|Cholesterol (Total and HDL)|Abnormality in Fetal Heart Rate or Rhythm, Unspecified as to Episode of Care
Interventions: OTHER: Physical exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: MR Guided Focused Ultrasound Treatment of Uterine Fibroids With Enhanced Sonication
Status: COMPLETED
Conditions: Uterine Leiomyoma|Uterine Fibroids
Interventions: DEVICE: ExAblate Enhanced Sonication
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Listening to Mom in the NICU: Neural, Clinical and Language Outcomes
Status: COMPLETED
Conditions: Premature Birth
Interventions: BEHAVIORAL: Language Treatment|BEHAVIORAL: Control Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Biosimilarity Study of Intravenous Recombinant Human Erythropoietin in Healthy Volunteers
Status: NOT_YET_RECRUITING
Conditions: Healthy
Interventions: BIOLOGICAL: Experimental Erythropoietin subcutaneous injection single dose of 4,000 IU|BIOLOGICAL: Active comparator Erythropoietin subcutaneous injection single dose of 4,000 IU
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Natural Sunlight Protection and Simulated Sunlight Protection Offered by Sunscreens and Fabrics
Status: ENROLLING_BY_INVITATION
Conditions: Sunburn|Sun Damaged Skin|Overexposure to Sun Rays
Interventions: DRUG: otc sunscreens|OTHER: sun protection fabrics|OTHER: Optical Filters
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Neoadjuvant Immune Checkpoint Blockade + a Prebiotic Food-enriched Dietary Intervention to Optimize Immune Response in Melanoma: NEO-PreFED
Status: NOT_YET_RECRUITING
Conditions: Melanoma
Interventions: DIETARY_SUPPLEMENT: Prebiotic Xnack Packouts
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: RAD001 in Patients With Chronic Phase Chronic Myeloid Leukemia w/ Molecular Disease.
Status: WITHDRAWN
Conditions: Chronic Myeloid Leukemia
Interventions: DRUG: RAD001|DRUG: Imatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Outcomes of Intraoperative 5-Fluorouracil Versus Mitomycin C
Status: COMPLETED
Conditions: Glaucoma
Interventions: DRUG: 5-fluorouracil|DRUG: Mitomycin C
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Phase 1/2 Safety Study of Intratumorally Dosed INT230-6
Status: COMPLETED
Conditions: Breast Cancer|Head and Neck Cancer|Squamous Cell Carcinoma|Lymphoma|Pancreatic Cancer|Liver Cancer|Colon Cancer|Lung Cancer|Bile Duct Cancer|Chordoma of Sacrum|Sarcoma
Interventions: DRUG: INT230-6|BIOLOGICAL: anti-PD-1 antibody|BIOLOGICAL: anti-CTLA-4 antibody
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bowel And Bladder Function in Infant Toilet Training
Status: ACTIVE_NOT_RECRUITING
Conditions: Infantile Colic|Constipation - Functional|Bladder Dysfunction|Toilet Training
Interventions: BEHAVIORAL: Assisted Infant Toilet Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of APD421 With and Without Ondansetron
Status: COMPLETED
Conditions: Postoperative Nausea and Vomiting
Interventions: DRUG: APD421|DRUG: Placebo|DRUG: Ondansetron
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Chemotherapy, Total-Body Irradiation, Donor Natural Killer Cell Infusion, Aldesleukin, and UCB Transplant in Treating Patients With Relapsed or Refractory AML
Status: TERMINATED
Conditions: Leukemia
Interventions: BIOLOGICAL: aldesleukin|DRUG: cyclophosphamide|DRUG: fludarabine phosphate|PROCEDURE: umbilical cord blood transplantation|RADIATION: total-body irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Patient Comfort After Two Anesthetic Protocols for Injections Into the Eye
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: 4% lidocaine|DRUG: 3.5% ophthalmic lidocaine gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Kinesio Taping and Cervical Thrust Manipulation in Neck Pain
Status: COMPLETED
Conditions: Neck Pain
Interventions: OTHER: Kinesio taping group|OTHER: Cervical thrust manipulation group|OTHER: Conventional therapy group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Tirofiban for Patients With BAD (BRANT)
Status: RECRUITING
Conditions: Branch Atheromatous Disease
Interventions: DRUG: Tirofiban|DRUG: Aspirin tablet|DRUG: Clopidogrel tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Omega-3 Fatty Acids for Prevention of Post-Operative Atrial Fibrillation
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DRUG: Omega -3 fatty acids|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of the Effects of Turkish Get Up Exercise and Stabilization Exercises on Muscular Activation, Core Stability and Upper Extremity Performance in Healthy Individuals
Status: COMPLETED
Conditions: Physical Therapy
Interventions: OTHER: Turkish Get Up exercise|OTHER: Core Stability exercise|OTHER: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BMT-CARE: Psychosocial Intervention for Transplant Caregivers
Status: NOT_YET_RECRUITING
Conditions: Bone Marrow Transplant Complications|Hematologic Malignancy
Interventions: BEHAVIORAL: BMT-CARE|BEHAVIORAL: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Patient Priorities for Survivorship Care in Older Breast Cancer Survivors
Status: NOT_YET_RECRUITING
Conditions: Breast Cancer Survivorship
Interventions: BEHAVIORAL: Adapted Patient Priorities Care (PPC) approach|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Absolute Coronary Flow in Patients With Heart Failure With Reduced Ejection Fraction and Left Bundle Branch Block With Cardiac Resynchronization Therapy
Status: RECRUITING
Conditions: Left Bundle-Branch Block|Heart Failure|Cardiac Resynchronization Therapy|Dilated Cardiomyopathy
Interventions: PROCEDURE: Intracoronary flow and pressure
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Renin-Guided Therapeutics in the Management of Untreated, Uncontrolled, or Complicated Hypertension
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: clinical hypertension specialist-no specific med. Any anti-hypertension meds.|DRUG: renin guided therapeutics-no specific med. Any anti-hypertensive med.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Losartan for Improved Vascular Endothelial Function After Preeclampsia
Status: RECRUITING
Conditions: Preeclampsia Postpartum
Interventions: DRUG: Losartan Potassium|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Improving Screening and Therapy for Hispanic/Latinx at Risk for CKD
Status: RECRUITING
Conditions: Type 2 Diabetes|Chronic Kidney Diseases
Interventions: DIAGNOSTIC_TEST: BP|DIAGNOSTIC_TEST: HbA1c|BEHAVIORAL: PCP Guidelines for Screening and Monitoring Hispanic/Latinx patients for CKD
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effectiveness of a Psychoeducative Intervention on Patients With Cronic Low Back Pain
Status: COMPLETED
Conditions: Back Pain Lower Back Chronic
Interventions: OTHER: Pain Neuroscience Education" (PNE)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Morphine Gel Topically in Patients With Stage 2-3 Wounds
Status: UNKNOWN
Conditions: Wounds
Interventions: DRUG: morphine topical gel|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Treatment Modalities in Poor Responders Undergoing IVF
Status: COMPLETED
Conditions: Poor Responders
Interventions: DRUG: Letrozole|DRUG: human menopausal gonadotropin (hMG)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunotherapy of Advanced Cancer Using a Combination Nimotuzumab and NK Cells
Status: UNKNOWN
Conditions: Advanced Cancer|ADCC|NK Cell Mediated Immunity|Nimotuzumab|Adaptive Transfer
Interventions: BIOLOGICAL: NK Cell adaptive transfer|DRUG: Nimotuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Aronia Melanocarpa Extract on Obese Individuals With Impaired Fasting Blood Glucose
Status: NOT_YET_RECRUITING
Conditions: Obesity
Interventions: DIETARY_SUPPLEMENT: aronia melanocarpa extract
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Test-retest Evaluation of [18F]MNI-958 PET
Status: COMPLETED
Conditions: Healthy Volunteers|Alzheimer Disease|Progressive Supranuclear Palsy
Interventions: DRUG: [18F]MNI-958
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Efficacy and Safety of Dexlansoprazole on Heartburn Relief in Chinese Patients
Status: COMPLETED
Conditions: Heartburn|Gastroesophageal Reflux Disease
Interventions: DRUG: Dexlansoprazole|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Contingency Management for the Treatment of Co-Occurring Alcohol and Drug Misuse
Status: COMPLETED
Conditions: Co-Occurring Alcohol and Drug Misuse
Interventions: BEHAVIORAL: CM for Alcohol|BEHAVIORAL: CM for drugs|BEHAVIORAL: CM for both substances|BEHAVIORAL: Non-Contingent group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: WoO: Window of Opportunity Trial of Olaparib and Durvalumab in Histologically Proven EOC
Status: RECRUITING
Conditions: Epithelial Ovarian Cancer
Interventions: DRUG: olaparib|DRUG: durvalumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ceralasertib (AZD6738) Alone and in Combination With Olaparib or Durvalumab in Patients With Solid Tumors
Status: RECRUITING
Conditions: Clear Cell Renal Cell Carcinoma|Locally Advanced Pancreatic Cancer|Locally Advanced Malignant Solid Neoplasm|Metastatic Malignant Solid Neoplasm|Metastatic Renal Cell Carcinoma|Metastatic Urothelial Carcinoma|Metastatic Pancreatic Cancer|Stage III Pancreatic Cancer|Stage III Renal Cell Cancer|Stage IV Pancreatic Cancer|Stage IV Renal Cell Cancer|Endometrial Cancer|Metastatic Castration-resistant Prostate Cancer
Interventions: DRUG: Ceralasertib|DRUG: Olaparib|DRUG: Durvalumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Oral Sumatriptan Plus Oral Promethazine in Migraine Treatment
Status: COMPLETED
Conditions: Migraine With Aura|Migraine Without Aura
Interventions: DRUG: Sumatriptan+Promethazine (SPr)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Study of Gene-activated Bone Substitute and Xenogenic Bone Matrix in Alveolar Ridge Augmentation
Status: UNKNOWN
Conditions: Alveolar Bone Loss|Alveolar Ridge Pathology &#X7C; Gingiva &#X7C; Dental
Interventions: DEVICE: gene-activated bone substitute mixed with autobone
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Cidofovir in Treating HIV-Infected Patients With High-Grade Squamous Intraepithelial Lesions of the Skin Near the Anus
Status: COMPLETED
Conditions: Anal Cancer|Precancerous Condition
Interventions: DRUG: cidofovir|GENETIC: DNA methylation analysis|GENETIC: gene expression analysis|GENETIC: polymerase chain reaction|PROCEDURE: biopsy|PROCEDURE: histopathologic examination
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Genetics and Heart Health After Cancer Therapy
Status: COMPLETED
Conditions: Breast Cancer|Hereditary Breast/Ovarian Cancer (brca1, brca2)|Heart Diseases|Drug-Induced Cardiomyopathy
Interventions: DIAGNOSTIC_TEST: echocardiography|OTHER: Cardiopulmonary Exercise Testing|OTHER: Blood Collection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Midazolam and Ketamine Effect Administered Through the Nose for Sedation of Children for Dental Treatment
Status: COMPLETED
Conditions: Child Behavior|Dental Caries
Interventions: DRUG: Intranasal ketamine|DRUG: Oral ketamine|DRUG: Intranasal midazolam|DRUG: Oral midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Mechanism of Acupuncture for Chronic Sciatica Using fMRI
Status: UNKNOWN
Conditions: Chronic Sciatica
Interventions: DEVICE: Real acupuncture|DEVICE: Sham acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Digestibility of Fermotein™
Status: COMPLETED
Conditions: Digestive System
Interventions: OTHER: Fermotein™ dry powder porridge|OTHER: Fermotein™ wet porridge|OTHER: Fermotein™ modified wet porridge|OTHER: Mycoprotein porridge (matching control)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: The Safety and Effectiveness of Lamivudine Plus Zidovudine, Used With and Without 1592U89, in HIV-1 Infected Patients Who Have Never Taken Anti-HIV Drugs
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Abacavir sulfate|DRUG: Lamivudine|DRUG: Zidovudine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: Study Comparing Bevacizumab + Erlotinib vs Erlotinib Alone as First Line Treatment of Patients With EGFR Mutated Advanced Non Squamous Non Small Cell Lung Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-squamous Non-small Cell Lung Cancer
Interventions: DRUG: Erlotinib|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Aortic Stenosis in Brazil: Cost-Utility Analysis of TAVI vs SAVR
Status: ACTIVE_NOT_RECRUITING
Conditions: Aortic Stenosis
Interventions: PROCEDURE: TAVR - Transcatheter aortic valve replacement|PROCEDURE: Surgical aortic valve replacement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Potential Research Study Participant Registry
Status: COMPLETED
Conditions: Acne|Actinic Keratosis|Dysplastic Nevi|Eczema|Psoriasis|Skin Cancer|Rosacea|Leg Ulcers|Foot Ulcers|Atopic Dermatitis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase I, Multi-center, Open Label, Drug-drug Interaction Study to Assess the Effect of Ceritinib on the Pharmacokinetics of Warfarin and Midazolam in Patients With ALK-positive Advanced Tumors
Status: COMPLETED
Conditions: ALK-positive Advanced Tumors
Interventions: DRUG: ceritinib|DRUG: warfarin|DRUG: midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Comparison of the Onset Times and Durations of Actions of Different Local Anesthetic Mixture Solutions [CODLAM]
Status: COMPLETED
Conditions: Injury Arm
Interventions: DRUG: brachial plexus block for LB Group|DRUG: brachial plexus block for BS Group|DRUG: brachial plexus block for LS Group|DRUG: brachial plexus block for BL Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Phase I Study of ZD1839 and Palliative Thoracic Radiotherapy in Patients With Non-small-cell Lung Cancer
Status: COMPLETED
Conditions: Non-small-cell Lung Cancer
Interventions: DRUG: Gefitinib|PROCEDURE: palliative thoracic radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Selinexor in Combination With Ruxolitinib in Myelofibrosis
Status: RECRUITING
Conditions: Myelofibrosis
Interventions: DRUG: Selinexor|DRUG: Selinexor|OTHER: Placebo|DRUG: Ruxolitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Behavioral Activation Therapy for Rural Veterans With Diabetes and Depression
Status: COMPLETED
Conditions: Diabetes Mellitus|Depression
Interventions: BEHAVIORAL: Healthy Outcomes through Patient Empowerment (HOPE)|BEHAVIORAL: Enhanced Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: An Efficacy and Safety Study of Paliperidone Palmitate in Participants With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Paliperidone palmitate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical and Radiographic Evaluation of the Effect of Hyaluronic Acid Surface Treatment Versus Sandblasted Acid Etched on Stability of Delayed Dental Implant in Posterior Maxilla.
Status: NOT_YET_RECRUITING
Conditions: Missing Teeth|Bone Loss
Interventions: DRUG: Hyaluronic acid|DRUG: sandblasted, and acid-etched|PROCEDURE: Delayed dental implant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Irinotecan With or Without Oxaliplatin in Treating Patients With Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: irinotecan hydrochloride|DRUG: oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect Of Detrol LA With Behavioral Intervention In Overactive Bladder Subjects Dissatisfied With Recent OAB Medication.
Status: COMPLETED
Conditions: Urinary Incontinence
Interventions: DRUG: Tolterodine ER 4 mg QD|BEHAVIORAL: OAB Patient Behavioral Training Material
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CAR19 Donor Lymphocytes for Relapsed CD19+ Malignancies Following Allogeneic Transplantation
Status: COMPLETED
Conditions: CD19+ Malignancies: Relapse Post-allogeneic Transplant
Interventions: GENETIC: Infusion of modified CAR19 T-cells (4G7-CARD T-cells)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oxytocin to Treat PTSD
Status: RECRUITING
Conditions: PTSD
Interventions: DRUG: Oxytocin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Dexmedetomidine on Renal Function and Delayed Graft Function After Kidney Transplantation
Status: UNKNOWN
Conditions: Kidney Transplantation
Interventions: DRUG: Dexmedetomidine|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Observational Study of COVID-19 Treatment Efficacy
Status: TERMINATED
Conditions: Coronavirus|Coronavirus Infection|Corona Virus Infection|COVID|Sars-CoV2|Coronavirus as the Cause of Diseases Classified Elsewhere|SARS-Associated Coronavirus as Cause of Disease Classified Elsewhere|COVID-19|Coronavirus Disease|Coronavirus Sars-Associated as Cause of Disease Classified Elsewhere
Interventions: OTHER: No intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Cholesterol, Hypertension and Glucose Education Study
Status: COMPLETED
Conditions: Cardiovascular Disease|Diabetes
Interventions: BEHAVIORAL: Tailored cardiovascular risk management (Nurse-administered )
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Retinal and Retinal Pigment Epithelium (RPE) Autoimmunity in Age-related Macular Degeneration (AMD)
Status: COMPLETED
Conditions: Age Related Macular Degeneration
Interventions: DRUG: ranibizumab (Lucentis(R))
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fetoscopic NEOX Cord 1K® Spina Bifida Repair
Status: ACTIVE_NOT_RECRUITING
Conditions: Spina Bifida|Myelomeningocele|Myeloschisis
Interventions: DEVICE: NEOX Cord 1K
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Tolerability and Efficacy of Tamsulosin 0.4mg OCAS Formulation in Patients Who Are Unsatisfied With the Treatment of Tamsulosin 0.2mg Conventional Formulation
Status: COMPLETED
Conditions: Lower Urinary Tract Symptoms (LUTS) Associated With Benign Prostatic Hyperplasia (BPH)
Interventions: DRUG: Tamsulosin OCAS
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Safety and Tolerability of INCB019602 When Administered With Metformin in Patients With Type 2 Diabetes
Status: TERMINATED
Conditions: Type 2 Diabetes
Interventions: DRUG: INCB019602|DRUG: INCB019602|DRUG: INCB019602|DRUG: INCB019602|DRUG: INCB019602|DRUG: Placebo|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of Tadalafil, Tamsulosin and Combination for Access Sheath Deployment
Status: UNKNOWN
Conditions: Nephrolithiasis
Interventions: DRUG: Cialis 5Mg Tablet|DRUG: Flomax 0.4Mg Capsule|COMBINATION_PRODUCT: Cialis + Flomax|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Static Stretching Versus Post Facilitation Stretch of Iliopsoas in Non-Specific Low Back Pain
Status: RECRUITING
Conditions: Low Back Pain
Interventions: PROCEDURE: Core stability exercises|PROCEDURE: Static Stretching of Iliopsoas|PROCEDURE: Post Facilitation Stretch of Iliopsoas
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Persistent Viremia (Virus in Blood) in Chronic Hepatitis B Subjects Already Receiving Adefovir Dipivoxil
Status: COMPLETED
Conditions: Chronic Hepatitis B
Interventions: DRUG: tenofovir DF|DRUG: emtricitabine /tenofovir DF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vitamin B6 Can Prevent Hand and Foot Syndrome in Cancer Patients Capecitabine Chemotherapy
Status: TERMINATED
Conditions: Hand and Foot Syndrome
Interventions: DRUG: Vitamin B 6|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of Epiduo Associated With Lymecycline Versus Epiduo Vehicle Associated With Lymecycline in Acne Vulgaris
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: Adapalene/ BPO gel with Lymecycline capsules|DRUG: Adapalene/ BPO vehicle gel with Lymecycline capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Conversion of in Vitro Fertilization Cycles to Intrauterine Inseminations in Patients With a Poor Ovarian Response to Stimulation
Status: COMPLETED
Conditions: Infertility
Interventions: PROCEDURE: IVF / IVF-ICSI|PROCEDURE: IUI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Demonstrate the Safety and Effectiveness of the NIKKISO DBB-EXA ES Hemodialysis Delivery System
Status: COMPLETED
Conditions: Dialysis|Chronic Renal Failure
Interventions: DEVICE: DBB-EXA ES Hemodialysis System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Daily Pentoxifylline as a Rescue Treatment in Duchenne Muscular Dystrophy
Status: COMPLETED
Conditions: Muscular Dystrophy, Duchenne
Interventions: DRUG: Pentoxifylline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Rotator Cuff Healing Using a Nanofiber Scaffold in Patients Greater Than 55 Years
Status: ACTIVE_NOT_RECRUITING
Conditions: Rotator Cuff Tears
Interventions: DEVICE: nanofiber scaffold
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: POSTconditioning During Coronary Angioplasty in Acute Myocardial Infarction Study
Status: COMPLETED
Conditions: Myocardial Reperfusion Injury
Interventions: PROCEDURE: Postconditioning|PROCEDURE: Primary angioplasty and stenting without additional intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Fenofibrate Capsules, 130 mg Under Fasting Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Fenofibrate|DRUG: ANTARA® (fenofibrate)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Harnessing ECG Artificial Intelligence for Rapid Treatment and Accurate Interpretation, an Open Label Randomized Controlled Trial
Status: NOT_YET_RECRUITING
Conditions: Structural Heart Abnormality
Interventions: DEVICE: ECHONEXT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Time and Cost-implications of Intraoral Scans vs Alginate Impressions: A Randomised Controlled Trial
Status: NOT_YET_RECRUITING
Conditions: Chairside Time and Costs Associated With Intraoral Scanning Versus Alginate Impressions
Interventions: DEVICE: Alginate impression|DEVICE: Intraoral scan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Clinical and Neurophysiological Effects of tDCS to Visual and Motor Cortex in Migraine
Status: ACTIVE_NOT_RECRUITING
Conditions: Migraine
Interventions: DEVICE: transcranial direct stimulation|DEVICE: Sham treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Methylprednisolone During the Switch Between Natalizumab and Fingolimod
Status: UNKNOWN
Conditions: Multiple Sclerosis
Interventions: DRUG: Methylprednisolone|DRUG: Placebo|DRUG: natalizumab (NTZ)|DRUG: fingolimob (FTY)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Docosahexaenoic Acid (DHA) Supplementation in Amblyopia
Status: WITHDRAWN
Conditions: Amblyopia
Interventions: DRUG: Docosahexaenoic Acid|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Oprozomib and Dexamethasone,in Combination With Lenalidomide or Oral Cyclophosphamide to Treat Newly Diagnosed Multiple Myeloma
Status: TERMINATED
Conditions: Multiple Myeloma
Interventions: DRUG: Oprozomib|DRUG: Lenalidomide|DRUG: Dexamethasone|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Patent Foramen Ovale Closure or Anticoagulants Versus Antiplatelet Therapy to Prevent Stroke Recurrence
Status: COMPLETED
Conditions: Ischemic Stroke|Patent Foramen Ovale|Atrial Septal Aneurysm|Migraine
Interventions: DRUG: aspirin|DRUG: Antivitamins K or rivaroxaban or dabigatran or apixaban|DEVICE: Devices for PFO closure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Memantine for Neuroprotection and Cognitive Enhancement Following Traumatic Brain Injury
Status: COMPLETED
Conditions: Traumatic Brain Injury
Interventions: DRUG: Memantine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Myocardial Ischemic-Reperfusion Injury During Off- and On- Pump CABG
Status: COMPLETED
Conditions: Ischemic Heart Disease|Coronary Artery Disease|Ischemic Reperfusion Injury|CABG
Interventions: PROCEDURE: On-Pump CABG.|PROCEDURE: Off-Pump CABG.|PROCEDURE: BH-CABG MSC.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effectiveness of Transcranial Direct Current Stimulation (tDCS) in Decreasing Food Cravings
Status: COMPLETED
Conditions: Craving
Interventions: DEVICE: real tDCS|DEVICE: sham tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Comparison of Time Taken for Intubation and Cormack Lehane View Between C-Mac With Glidescope Video Laryngoscopy in Paediatric Patients
Status: COMPLETED
Conditions: Paediatric Airway
Interventions: DEVICE: Glidescope video laryngoscopy/ C-MAC video laryngoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Comparing Hypofractionated Radiotherapy Boost to Conventionally Fractionated
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: RADIATION: Hypofractionated IMRT boost radiotherapy|RADIATION: Conventional Fractionated IMRT boost radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Internalized Stress in Relation to Alcohol Consumption
Status: RECRUITING
Conditions: Stress, Physiological|Ethanol Intoxication|Distress, Emotional
Interventions: BEHAVIORAL: Relevant Trier Social Stressor Test (TSST)|DRUG: Ethanol|BEHAVIORAL: Placebo Trier Social Stressor Test (TSST)|BEHAVIORAL: Placebo Beverage|BEHAVIORAL: Irrelevant Trier Social Stressor Test (TSST)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy of Guedes-Pinto Paste and CTZ Paste in the Non-instrumental Endodontic Treatment of Primary Teeth
Status: NOT_YET_RECRUITING
Conditions: Necrotic Pulp
Interventions: PROCEDURE: Irrigation|PROCEDURE: Filling with Guedes-Pinto Paste|PROCEDURE: Filling with CTZ Paste
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prognosis of Resection and Radiotherapy in the Treatment of Intrahepatic Cholangiocarcinoma Patients
Status: UNKNOWN
Conditions: Intrahepatic Cholangiocarcinoma
Interventions: PROCEDURE: Resection|RADIATION: Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety, Tolerability and Plasma Concentration Profiles of MK0633 in Asthmatic Children Aged 12 to Less Than 16 Years (0633-019)
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Comparator: MK0633
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT