pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Use of Fractional CO2 Laser for the Treatment of Vulvovaginal Atrophy: a Double-blinded Randomized Placebo-controlled Clinical Trial.
Status: COMPLETED
Conditions: Vulvovaginal Atrophy
Interventions: PROCEDURE: Vaginal laser application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Remineralization Agents for the Treatment of White Spot Lesions
Status: TERMINATED
Conditions: White Spot Lesion of Tooth
Interventions: OTHER: Clinpro® 5% sodium fluoride plus tri calcium phosphate varnish|OTHER: Tooth Mousse® - Casein phosphopeptide-Amorphous calcium phosphate (CPP - ACP)s|OTHER: MI Paste® -Casein phosphopeptide-Amorphous calcium phosphate fluoride (CPP-ACPF)|OTHER: Zap® 1.23% APF gel - Acidulated phosphate fluoride|OTHER: Listerine fluoride mouthrinse
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Relationship Between NLR and PONV and ESPB
Status: NOT_YET_RECRUITING
Conditions: Erector Spinae Plane Block|Neutrophil to Lymphocyte Ratio
Interventions: PROCEDURE: Erector Spinae Plane Block|PROCEDURE: 0.9% physiological saline (20ml) injection under ultrasound-guided Erector Spinae Plane Block (ESPB).
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Study Comparing the Effect of Dasatinib and Imatinib on Malignant Stem Cells in Chronic Myeloid Leukemia
Status: COMPLETED
Conditions: Chronic Myeloid Leukemia
Interventions: DRUG: Imatinib|DRUG: Dasatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Functional Versus IADT Splinting Times on Tooth Mobility After Surgical Extrusion
Status: UNKNOWN
Conditions: Dental Trauma
Interventions: PROCEDURE: Functional splinting time
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CHARGE: Controlling Hunger and ReGulating Eating
Status: COMPLETED
Conditions: Binge-Eating Disorder|Overweight|Obesity
Interventions: BEHAVIORAL: Regulation of Cues (ROC)|BEHAVIORAL: Cognitive Behavior Therapy (CBT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of the HighLife Transcatherter Mitral Valve Replacement System in Patients With Moderate-severe or Severe Mitral Regurgitation in China
Status: RECRUITING
Conditions: Mitral Regurgitation
Interventions: DEVICE: the HighLife Trans-Septal Transcatheter Mitral Valve Replacement System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Molecular and Clinical Risk-Directed Therapy for Infants and Young Children With Newly Diagnosed Medulloblastoma
Status: RECRUITING
Conditions: Medulloblastoma
Interventions: PROCEDURE: Surgical resection|PROCEDURE: Ommaya/VPS|DRUG: Methotrexate|DRUG: Cisplatin|DRUG: Vincristine|DRUG: Cyclophosphamide|DRUG: Carboplatin|DRUG: Topotecan|DRUG: Etoposide|DRUG: Pegfilgrastim|DRUG: Filgrastim|RADIATION: Irradiation|OTHER: Educational and Media Intervention|OTHER: SOC, Educational and Media Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Newborn Basic Care Training on Fathers' Self-Efficacy and Father-Baby Attachment
Status: NOT_YET_RECRUITING
Conditions: Newborn Basic Care Training
Interventions: OTHER: Newborn Basic Care Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: BIFI-OBESE: Clinical Trial in Paediatric Obesity
Status: COMPLETED
Conditions: Obesity, Childhood
Interventions: DRUG: Bifidobacterium breve BR03 and Bifidobacterium breve B632|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Atherosclerotic Lesion Proteomics by Harvesting Angioplasty Balloons (ALPHA).
Status: UNKNOWN
Conditions: Angina, Stable|Angina, Unstable|Non-ST-Segment Elevation Myocardial Infarction (NSTEMI)|ST-segment Elevation Myocardial Infarction (STEMI)|Vascular Diseases
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Ability of pCLE and WLE for Diagnosis and Cancer Tissue Acquisition in Advanced Gastric Cancer After Chemotherapy Status
Status: UNKNOWN
Conditions: Advanced Gastric Cancer|Neoadjuvant Chemotherapy|Palliative Chemotherapy
Interventions: DEVICE: Confocal group|DEVICE: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Quality Control of CE-Certified Phonak Hearing Aids - 2017_37
Status: COMPLETED
Conditions: Hearing Loss, Sensorineural
Interventions: DEVICE: Successor of Phonak Audéo B-Direct|DEVICE: Phonak Audéo B-Direct
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study of RC48-ADC in Subjects With HER2 Positive Metastatic or Unresectable Urothelial Cancer
Status: COMPLETED
Conditions: Urothelial Carcinoma|Advanced Cancer
Interventions: DRUG: RC48-ADC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing Allogeneic Hematopoietic Cell Transplantation Versus Best Available Standard of Care Therapy in Elderly Patients With Acute Myeloid Leukemia
Status: RECRUITING
Conditions: Acute Myeloid Leukemia
Interventions: PROCEDURE: Hematopoietic stem cell transplantation|DRUG: Best chemotherapy treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transrectal Ultrasound Imaging of the Prostate Gland and Neurovascular Bundles During Robot-Assisted Laparoscopic Radical Prostatectomy
Status: TERMINATED
Conditions: Prostate Cancer
Interventions: DEVICE: TRUS-RALRP
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mouth Dissolving Mosapride Tables Enhance Post Cesarean Gut Recovery
Status: COMPLETED
Conditions: Prevention of Postoperative Ileus
Interventions: DRUG: Mosapride|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Investigating the Circulating Sphingolipidome Response to a Single High-intensity Interval Training Session
Status: ACTIVE_NOT_RECRUITING
Conditions: Physiological Response of Sphingolipids to a Single HIIT Session
Interventions: OTHER: HIIT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Elastographic and Ultrasonographic Evaluation of Patients With Breast Cancer Related Lymphedema
Status: COMPLETED
Conditions: Lymphedema of Upper Arm|Stiffness of Hand, Not Elsewhere Classified|Evaluations, Diagnostic Self
Interventions: DIAGNOSTIC_TEST: Shear Wave Elastography and B Mode Ultrasonography|DIAGNOSTIC_TEST: Quick Dash Questionnare|DIAGNOSTIC_TEST: The Lymphedema Life Impact Scale|DIAGNOSTIC_TEST: Questioning lymphedema-related symptoms|OTHER: Extremity circumference and volume measurement
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Functional Taping on Static Postural Control in Patients With Non-specific Chronic Low Back Pain
Status: COMPLETED
Conditions: Low Back Pain
Interventions: PROCEDURE: Functional Star-shape taping (SFT)|PROCEDURE: Sham Functional Taping (Sham-FT)|BEHAVIORAL: Minimal Intervention Strategy (MIS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Safety, Tolerability and Pharmacokinetics With BAT8010 for Injection in Advanced Malignant Solid Tumors Patients
Status: RECRUITING
Conditions: Advanced or Metastatic Solid Tumors
Interventions: DRUG: BAT8010 for Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy With or Without Peripheral Stem Cell Transplantation, Radiation Therapy, and/or Surgery in Treating Patients With Ewing's Sarcoma
Status: UNKNOWN
Conditions: Sarcoma
Interventions: BIOLOGICAL: dactinomycin|DRUG: busulfan|DRUG: doxorubicin hydrochloride|DRUG: etoposide|DRUG: ifosfamide|DRUG: melphalan|DRUG: vincristine sulfate|PROCEDURE: autologous hematopoietic stem cell transplantation|PROCEDURE: conventional surgery|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Analysis of the Impact of Helicobacter Pylori on Salivary Microbiome in Adults
Status: UNKNOWN
Conditions: Helicobacter Pylori Infection
Interventions: DRUG: Esomeprazole|DRUG: Amoxicillin|DRUG: Bismuth Potassium Citrate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Placebo- and Active Controlled Study of Preladenant in Subjects With Moderate to Severe Parkinson's Disease (P04938)
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: DRUG: Preladenant 2 mg tablet|DRUG: Preladenant 5 mg tablet|DRUG: Preladenant 10 mg tablet|DRUG: Placebo to Preladenant Tablet|DRUG: Rasagiline 1 mg capsule|DRUG: Placebo to Rasagiline capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rivastigmine Patch Compared to Melatonin Patch in Prevention of Postoperative Delirium
Status: COMPLETED
Conditions: Delirium
Interventions: DRUG: Rivastigmine Transdermal System [Exelon]|DRUG: Melatonin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of Valcyte (Valganciclovir) Syrup Formulation in Pediatric Solid Organ Transplant Recipients
Status: COMPLETED
Conditions: Cytomegalovirus Infections
Interventions: DRUG: valganciclovir [Valcyte]
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acetyl Salicylic Elimination Trial JAPAN: The ASET JAPAN Pilot Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Coronary Syndrome|Non ST Segment Elevation Acute Coronary Syndrome
Interventions: DRUG: prasugrel Monotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Safety of Modified XELOX(mXELOX) Plus Cetuximab vs FOLFOX Plus Cetuximab in RAS and BRAF WT mCRC Pts
Status: RECRUITING
Conditions: Colo-rectal Cancer
Interventions: DRUG: Experimental: mXELOX plus cetuximab|DRUG: Active Comparator: FOLFOX plus cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating NEOadjuvant Immunotherapy in Resectable PANCreatic Ductal Adenocarcinoma
Status: TERMINATED
Conditions: Pancreatic Ductal Adenocarcinoma
Interventions: DRUG: Atezolizumab|DRUG: PEGPH20
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bisphenol A and Muscle Insulin Sensitivity
Status: COMPLETED
Conditions: Insulin Sensitivity|Glucose Metabolism Disorders|Microtia
Interventions: BEHAVIORAL: bisphenol A|BEHAVIORAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Aquatic Training on Motor Function in Children With Autism Spectrum Disorder
Status: RECRUITING
Conditions: Autism Spectrum Disorder
Interventions: OTHER: Aquatic Exercises|OTHER: Land Exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Influenza Vaccine Dose-Response in Infants and Toddlers: Immunogenicity and Reactogenicity
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Inactivated Influenza Vaccine Trivalent Types A and B (Split Virion)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Autologous Stem Cells Derived From Lipoaspirates for the Non-Surgical Treatment of Complex Perianal Fistula
Status: UNKNOWN
Conditions: Anal Fistula
Interventions: PROCEDURE: Non-surgical autologous implant of ASCs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Erythropoietin NeuroProtective Effect: Assessment in CABG Surgery (TENPEAKS)
Status: COMPLETED
Conditions: Cardiac Surgery|Brain Injury
Interventions: DRUG: Human recombinant erythropoietin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Kinesiotaping and Constraint Induced Movement Therapy in Subacute Stroke
Status: COMPLETED
Conditions: Stroke
Interventions: DEVICE: Kinesiotaping|BEHAVIORAL: modified Constraint Induced Movement Training|DEVICE: Sham taping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transversus Abdominis Plane Block Plus Quadratus Lumborum Block or Retrolaminar Block of Multiple Injections for Postoperative Analgesia Following Laparoscopic Colorectal Surgery
Status: UNKNOWN
Conditions: Quadratus Lumborum Block|Analgesia|Laparoscopic|Colorectal
Interventions: PROCEDURE: Retrolaminar block on the operative side|PROCEDURE: Quadratus lumborum block on the operative side|PROCEDURE: Transversus abdominis plane block on the nonoperative side
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Primary Objective of This Study Was to Investigate the Effect of Insulin on Myocardial Perfusion and Cardiac Function in Patients Undergoing Cardiac Surgery for CPB Using Transesophageal Echocardiography (TEE) to Detect CSBF
Status: COMPLETED
Conditions: Insulin
Interventions: DRUG: Glucose insulin potassium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study to Assess the Safety & Tolerability of a PARP Inhibitor in Combination With Gemcitabine in Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Neoplasms
Interventions: DRUG: KU-0059436 (AZD2281)(PARP inhibitor)|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PSMA-PET/MRI for Radiation Treatment Planning in Patients With Locally Metastatic Prostate Cancer: A Pilot Study
Status: COMPLETED
Conditions: Metastatic Prostate Cancer
Interventions: DRUG: [68Ga]PSMA-PET/MRI or PET/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety and Immunogenicity of Hecolin® in Healthy Pregnant Women
Status: NOT_YET_RECRUITING
Conditions: Hepatitis E Infection
Interventions: BIOLOGICAL: Hecolin® (Recombinant Hepatitis E Vaccine (Escherichia coli)).|OTHER: Isotonic Sodium Chloride injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of Increased Dose of TA-650 (Infliximab) in Patients With Crohn's Disease (CD)
Status: COMPLETED
Conditions: Crohn's Disease
Interventions: DRUG: TA-650
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sequential AG and mFOLFOX Combined With Serplulimab Injection and Bevacizumab Injection in Untreated Advanced Pancreatic Cancer
Status: RECRUITING
Conditions: Non-Resectable Pancreas Carcinoma
Interventions: DRUG: Sequential AG and mFOLFOX in Combination With Serplulimab Injection and Bevacizumab Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects Obtained at Manual Function After Applying Anodic Transcranial Direct Current Stimulation (tCDS) in Children With Spastic Hemiparetic Cerebral Palsy
Status: NOT_YET_RECRUITING
Conditions: Hemiparetic Cerebral Palsy
Interventions: DEVICE: Anodic Transcranial Direct Current Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Sublingual Immunotherapy in Patients With Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis|Effects of Immunotherapy
Interventions: DRUG: Mite extract sublingual immunotherapy (SLIT)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Daily Disposable Novel Multifocal Contact Lens in a Myopic Population
Status: COMPLETED
Conditions: Visual Acuity
Interventions: DEVICE: JJVC Investigational Multifocal Contact Lens (senofilcon A c3)|DEVICE: Dailies Total 1® Multifocal Contact Lens
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Distraction Methods Used During Inhalation Therapy on Children's Fear and Anxiety
Status: ACTIVE_NOT_RECRUITING
Conditions: Child|Inhalation Therapy; Complications|Fear|Distraction Methods|Anxiety
Interventions: BEHAVIORAL: Children's Fear and Anxiety normal nebulizer and mask+ distraction|BEHAVIORAL: Children's Fear and Anxiety a toy nebulizer and a toy mask
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Smartphone-Assisted Brief Behavioral Intervention for Pregnant Women With Depression
Status: COMPLETED
Conditions: Perinatal Depression
Interventions: BEHAVIORAL: Motherly 1.0|BEHAVIORAL: Brief Psychotherapy|BEHAVIORAL: Educational app
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Family Based Cognitive-Behavioral Treatment for Preschoolers With Obsessive Compulsive Disorder
Status: COMPLETED
Conditions: Obsessive Compulsive Disorder (OCD)
Interventions: BEHAVIORAL: Cognitive Behavioral Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: High-Intensity Interval Training On Women With Polycystic Ovary Syndrome.
Status: COMPLETED
Conditions: Polycystic Ovary Syndrome
Interventions: OTHER: High intensity interval training|OTHER: Strength training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Perioperative Telemonitoring to Optimize Cancer Care and Outcomes
Status: ACTIVE_NOT_RECRUITING
Conditions: Malignant Digestive System Neoplasm
Interventions: OTHER: Best Practice|BEHAVIORAL: Health Education|OTHER: Medical Device Usage and Evaluation|OTHER: Quality-of-Life Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Immediate Effect of Proponent-Nasal-Spray on Unspecific Discomfort in the Nose
Status: COMPLETED
Conditions: Unspecified Disorder of Nose and Nasal Sinuses
Interventions: OTHER: Proponent Nasal Spray
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Virtual Reality Glasses on Fear of Birth, Delivery Time and Non-Stress Test Results in Pregnancy in the Process of Labor
Status: ENROLLING_BY_INVITATION
Conditions: Virtual Reality
Interventions: OTHER: Group watching virtual reality glasses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Efficacy Study of Abdominal Massage Therapy to Treat Generalized Anxiety Disorder of Deficiency of Both Heart and Spleen Type
Status: UNKNOWN
Conditions: Anxiety Disorders
Interventions: OTHER: Abdominal Massage Therapy|DRUG: Buspirone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phenotypic Drug Probes as Predictors of Drug-drug Interactions With Tacrolimus
Status: COMPLETED
Conditions: Drug Interactions|Kidney Transplantation
Interventions: DRUG: Voriconazole|DRUG: Rifampin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Motor Cortex Stimulation for the Treatment of Chronic Facial, Upper Extremity, and Throat Pain.
Status: TERMINATED
Conditions: Trigeminal Neuralgia (Burchiel Type I)|Trigeminal Neuralgia (Burchiel Type II)|Trigeminal Neuropathic Pain|Trigeminal Deafferentation Pain|Complex Regional Pain Syndrome (Types I and II, Involving the Upper Extremity)|Glossopharyngeal Neuralgia|Upper Extremity Pain Due to Deafferentation of the Cervical Spine|Central Pain Syndromes
Interventions: DEVICE: Epidural Motor Cortex Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of α-lipoic Acid Treatment in Patient With Cardiac Autonomic Neuropathy
Status: COMPLETED
Conditions: Type 2 Diabetes|Cardiac Autonomic Neuropathy
Interventions: DRUG: α-lipoic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Primary Hyperparathyroidism (PHPT): Early Effect of Vitamin D
Status: WITHDRAWN
Conditions: Primary Hyperparathyroidism|Hypercalcemia|Vitamin D Deficiency|Osteoporosis|Osteopenia
Interventions: DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: Vitamin D3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: A Clinical Trial Targeting CEA Chimeric Antigen Receptor T (CAR-T) for CEA Positive Advanced Malignant Solid Tumors
Status: RECRUITING
Conditions: Colorectal Cancer|Esophagus Cancer|Gastric Cancer|Pancreas Cancer|Non-small Cell Lung Cancer|Breast Cancer|Bile Duct Cancer
Interventions: BIOLOGICAL: CEA-targeted CAR-T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Efficacy and Safety of RPH-104 Treatment in Patients With Idiopathic Recurrent Pericarditis
Status: COMPLETED
Conditions: Pericarditis
Interventions: BIOLOGICAL: RPH-104|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy and Monoclonal Antibody Therapy in Treating Patients With Advanced Colorectal Cancer With Liver Metastases or Lung Metastases That Are Potentially Removable by Surgery
Status: UNKNOWN
Conditions: Colorectal Cancer|Metastatic Cancer
Interventions: BIOLOGICAL: bevacizumab|BIOLOGICAL: cetuximab|DRUG: fluorouracil|DRUG: irinotecan hydrochloride|DRUG: leucovorin calcium|DRUG: oxaliplatin|OTHER: laboratory biomarker analysis|PROCEDURE: adjuvant therapy|PROCEDURE: biopsy|PROCEDURE: conventional surgery|PROCEDURE: neoadjuvant therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Smell Changes & Efficacy of Nasal Theophylline
Status: COMPLETED
Conditions: Olfactory Disorder|Anosmia|Viral Infection|Theophylline Causing Adverse Effects in Therapeutic Use|Smell Disorder
Interventions: DRUG: Theophylline|DRUG: Saline Nasal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Axial Stability of Two Models of Intraocular Lenses in Patients With an Eye Length More Than 26 mm
Status: COMPLETED
Conditions: Cataract Senile|Myopia, High-Grade|Corneal Astigmatism
Interventions: PROCEDURE: IOL Clareon AutonoMe|PROCEDURE: IOL Hoya iSert 251
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Total Neoadjuvant Therapy With mFOLFOX and Short-course Radiation in Resectable Rectal Cancer
Status: RECRUITING
Conditions: Rectal Cancer
Interventions: DRUG: Chemotherapy|RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessing Immune Response of Different COVID-19 Vaccines in Older Adults
Status: COMPLETED
Conditions: Vaccination Reaction|COVID-19|Vaccination; Infection
Interventions: BIOLOGICAL: Comirnaty(BTN162b2)|BIOLOGICAL: Spikevax (mRNA-1273)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Haemodynamic Abnormalities Recorded With Cardiac Catheterization Along With Body's Surface Micro-accelerometers (KT-KCG)
Status: WITHDRAWN
Conditions: Heart Failure|Pulmonary Hypertension
Interventions: DEVICE: Ballistocardiography and seismocardiography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Oral Fexinidazole Dosing Regimens for the Treatment of Adults With Chronic Indeterminate Chagas Disease
Status: COMPLETED
Conditions: Chagas' Disease (Chronic) Nos
Interventions: DRUG: Fexinidazole|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Endostar Combined With Induction Chemotherapy and Concurrent Chemoradiotherapy for Locoregional Nasopharyngeal Carcinoma
Status: UNKNOWN
Conditions: Nasopharyngeal Carcinoma
Interventions: DRUG: Endostar|DRUG: Cisplatin|DRUG: Docetaxel|RADIATION: Intensity Modulated Radiation Therapy (IMRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Tai Chi on Osteoarthritic Knee Pain in Elders With Mild Dementia
Status: COMPLETED
Conditions: Osteoarthritis, Knee|Dementia
Interventions: BEHAVIORAL: Tai Chi|BEHAVIORAL: Attention control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Effectiveness of Axicabtagene Ciloleucel Compared to Standard of Care Therapy in Patients With Relapsed/Refractory Diffuse Large B Cell Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Relapsed/Refractory Diffuse Large B-Cell Lymphoma (DLBCL)
Interventions: BIOLOGICAL: Axicabtagene Ciloleucel|DRUG: Platinum-containing salvage chemotherapy (eg, R-ICE) followed by high dose therapy (eg, BEAM) and autologous stem cell transplant in responders.|DRUG: Cyclophosphamide|DRUG: Fludarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Exergaming in Adittion to Conventional Treatment for Physical Therapy in People With Multiple Sclerosis
Status: RECRUITING
Conditions: Multiple Sclerosis
Interventions: OTHER: Conventional Therapy|DEVICE: Nintendo Ring Fit Adventure + Conventional Therapy|DEVICE: Nintendo Wii Fit + Conventional Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Brain Plasticity of Autism in Response to Early Behavioral Intervention: A Multimodal MRI Study
Status: RECRUITING
Conditions: Autism
Interventions: BEHAVIORAL: Behavior modification|BEHAVIORAL: Behavior modification and sensory integration training|BEHAVIORAL: Behavior modification and applied behavioral analysis|BEHAVIORAL: Behavior modification and TEACCH
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of Dasatinib vs. High-Dose Imatinib (600 mg) in Patients With Chronic Phase Chronic Myeloid Leukemia (CML) Who Failed to Achieve Complete Cytogenetic Response After 3-18 Months of Imatinib Therapy
Status: TERMINATED
Conditions: Leukemia
Interventions: DRUG: Dasatinib|DRUG: Imatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Impact of Abdominal Wall Reconstruction on Abdominal Wall Tension and Intra-Abdominal Pressure
Status: RECRUITING
Conditions: Ventral Hernia|Incisional Hernia|Parastomal Hernia
Interventions: DEVICE: Abdominal wall tension|DEVICE: Intra-abdominal pressure
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Impact of Fever Prevention in Brain Injured Patients
Status: TERMINATED
Conditions: Fever|Ischemic Stroke|Intracerebral Hemorrhage|Subarachnoid Hemorrhage
Interventions: DEVICE: Targeted Temperature Management|OTHER: Standard Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: NSS-2 BRIDGE Device in Post-Operative Pain Management
Status: COMPLETED
Conditions: Acute Pain|Surgery|Abdominal Cancer
Interventions: DEVICE: NSS-2 Bridge|DEVICE: Sham NSS-2 BRIDGE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of MB-CART2019.1 vs. SoC in Lymphoma Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Diffuse Large B-cell Lymphoma
Interventions: GENETIC: MB-CART2019.1|DRUG: R-GemOx or BR plus polatuzumab vedotin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Post-Sternotomy Dressings
Status: COMPLETED
Conditions: Impaired Wound Healing|Postoperative Wound Infection-deep
Interventions: OTHER: Dry Sterile Dressing|OTHER: Metallic Silver Dressing|OTHER: Ionic Silver Dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Clinical Evaluation of the "NICU Clinical Decision Support Dashboard" - CHMCO
Status: WITHDRAWN
Conditions: Preterm Birth|Low; Birthweight, Extremely (999 Grams or Less)|Neonatal Infection|Satisfaction|Stress|Chronic Lung Disease|Growth Acceleration|Adverse Event
Interventions: DEVICE: NICU Dashboard
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Effect of S-ketamine Combined With Sufentanil for Postoperative Analgesia in Patients Following Cesarean Section
Status: RECRUITING
Conditions: S-ketamine|Analgesia, Patient-Controlled|Cesarean Section
Interventions: DRUG: S-ketamine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Design and Validation of a Simulation-based Training Curriculum for Laparoscopic Bariatric Surgery
Status: COMPLETED
Conditions: Obesity
Interventions: PROCEDURE: Laparoscopic bariatric surgery ex-vivo training curriculum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Evaluation of Blood as a Submucosal Cushion During Endoscopic Polypectomy and Mucosal Resection
Status: COMPLETED
Conditions: Large Polyps in the Gastrointestinal Tract
Interventions: DRUG: Autologous blood injection|DRUG: Normal saline|DRUG: HPMC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aripiprazole Augmentation Versus Switching to Different Class of Antidepressants in Major Depressive Disorder
Status: UNKNOWN
Conditions: Major Depressive Disorder
Interventions: DRUG: Aripiprazole|DRUG: switching to different class of antidepressant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sacral Nerve Stimulation in Improving Bladder Function After Acute Traumatic Spinal Cord Injury
Status: TERMINATED
Conditions: Spinal Cord Injury, Acute|Neurogenic Bladder|Incontinence|Urinary Tract Infections
Interventions: DEVICE: PrimeAdvanced Surescan 97702 Neurostimulator - Medtronic (Minneapolis, MN)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety and Tolerability Study of MEDI-551, a B-cell Depleting Agent, to Treat Relapsing Forms of Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis, Relapsing Forms
Interventions: DRUG: MEDI-551 30 MG-IV|DRUG: MEDI-551 60 MG-SC|DRUG: PLACEBO-IV-SC|DRUG: MEDI-551 100 MG-IV|DRUG: MEDI-551 300 MG-SC|DRUG: MEDI-551 600 MG-IV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Examine the Feasibility of a Standardized Field Test for Marijuana and Alcohol Impairment: Laboratory Evaluations
Status: ACTIVE_NOT_RECRUITING
Conditions: Marijuana Impairment|Alcohol Impairment
Interventions: DRUG: Low Marijuana, Hash, THC, or Grass|DRUG: High Marijuana, Hash, THC, or Grass|DRUG: Placebo|DRUG: 0.05 BAC Alcohol|DRUG: 0.08 BAC Alcohol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: INtracorporeal Versus EXtracorporeal Anastomosis in Robotic Right Colectomy
Status: COMPLETED
Conditions: Colonic Cancer
Interventions: PROCEDURE: Intracorporeal anastomosis|PROCEDURE: Extracorporeal anastomosis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Quadratus Lumborum Block for Post-Cesarean Analgesia
Status: TERMINATED
Conditions: Postoperative Pain
Interventions: PROCEDURE: Quadratus Lumborum Block|PROCEDURE: Sham Block|DRUG: Intrathecal Morphine|DRUG: Intrathecal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety of Cultured Allogeneic Adult Umbilical Cord Derived Mesenchymal Stem Cells for Heart Disease
Status: RECRUITING
Conditions: Congestive Heart Failure|Angina
Interventions: BIOLOGICAL: AlloRx
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Diagnostic Utility of INS316 in Patients With Interstitial Lung Diseases (01-701)
Status: TERMINATED
Conditions: Interstitial Lung Disease
Interventions: DRUG: INS316 solution for inhalation|DRUG: hypertonic saline 3% sodium chloride solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Preoperative Marking of the Oral Resection Margin in Esophageal Cancer With a Surgical Fiducial Marker - First Experiences
Status: COMPLETED
Conditions: Esophagus Cancer, Adenocarcinoma
Interventions: OTHER: BioXmark™
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Abatacept in ANCA Associated Vasculitis
Status: TERMINATED
Conditions: ANCA-associated Vasculitis
Interventions: DRUG: Abatacept (Orencia)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Safety and Efficacy of Kalifilcon A Daily Disposable Contact Lens
Status: COMPLETED
Conditions: Contact Lens Wear
Interventions: DEVICE: Kalifilcon A Daily Disposable Contact Lenses|DEVICE: Biotrue ONEday Daily Disposable Contact Lenses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Hemolysis Related Complications in SCD. A Phase II Study With Voxelotor
Status: RECRUITING
Conditions: Sickle Cell Disease
Interventions: DRUG: Voxelotor 1500 mg oral per day (GBT440) for 48 weeks in patients with sickle-cell disease
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rejuvenated, Washed Packed Red Blood Cells in Pediatric Cardiac Surgery
Status: WITHDRAWN
Conditions: Heart Defects, Congenital
Interventions: DRUG: Rejuvesol|PROCEDURE: Cardiac surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Aerobic and Strength Training Exercise in Improving Fitness and Arm Health During and After Radiation Therapy in Patients With Stage II-III Breast Cancer
Status: COMPLETED
Conditions: Stage II Breast Cancer|Stage IIA Breast Cancer|Stage IIB Breast Cancer|Stage III Breast Cancer|Stage IIIA Breast Cancer|Stage IIIB Breast Cancer|Stage IIIC Breast Cancer
Interventions: OTHER: Best Practice|BEHAVIORAL: Exercise Intervention|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: ReIMAGINE Prostate Cancer Screening
Status: COMPLETED
Conditions: Prostate Cancer Screening|Prostate Cancer
Interventions: PROCEDURE: Magnetic Resonance Imaging (MRI)|PROCEDURE: Prostate-specific antigen (PSA) test
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Safety Study of rhASM Enzyme Replacement Therapy in Adults With Acid Sphingomyelinase Deficiency (Niemann-Pick Disease)
Status: TERMINATED
Conditions: Acid Sphingomyelinase Deficiency|Niemann-Pick Disease
Interventions: DRUG: rhASM|DRUG: rhASM|DRUG: rhASM|DRUG: rhASM|DRUG: rhASM
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Investigation of the Effects of a Royal Jelly and Bee Venom-Derived Skin Cream on Skin Health and Signs of Aging
Status: ACTIVE_NOT_RECRUITING
Conditions: Skin Health
Interventions: OTHER: Manuka Health Eternal Renewal Regenerating Face Cream with Royal Jelly and Bee Venom
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Innovations in Respiratory Muscles Training in Patients With Chronic Obstructive Pulmonary Disease. (INNOTORIO)
Status: COMPLETED
Conditions: COPD|Respiratory Muscles|Training
Interventions: OTHER: Respiratory muscle training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of a Caralluma Fimbriata Extract on Stress, Sleep and Neurotransmitters
Status: COMPLETED
Conditions: Stress|Sleep
Interventions: DRUG: Caralluma Fimbriata|DRUG: Placebo comparator - Microcrystalline cellulose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, and Pharmacokinetics of Switching From Oral Risperidone to Risperidone Implant
Status: COMPLETED
Conditions: Schizophrenia
Interventions: COMBINATION_PRODUCT: Risperidone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Penile Ischemia for Hypospadias Repair and The Patients and Surgeons Reported Outcomes
Status: COMPLETED
Conditions: Hypospadias|Hypospadias, Coronal|Hypospadia, Repair|Tourniquet
Interventions: PROCEDURE: Tourniquet|PROCEDURE: Non-tourniquet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Gastric Bypass Versus Best Medical Treatment on Progression of Carotid-intima Media Thickness in Type 2 Diabetes Mellitus (T2DM)
Status: UNKNOWN
Conditions: Atherosclerotic Cardiovascular Disease|Subclinical Disease and/or Syndrome
Interventions: DRUG: Intensive Medical Treatment|OTHER: IMM+Roux-en-Y Gastric Bypass (RYGBP)
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Intravenous Ketorolac and Metoclopramide for Pediatric Migraine in the Emergency Department
Status: COMPLETED
Conditions: Probable Migraine|Migraine With Aura|Migraine Without Aura
Interventions: DRUG: Ketorolac Tromethamine|DRUG: Metoclopramide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Integration of Guidelines for Comorbidities
Status: UNKNOWN
Conditions: Type 2 Diabetes Mellitus|Lung Diseases, Obstructive|Osteoporosis|Hypertension|Osteoarthritis
Interventions: OTHER: DSS for mitigating interactions between recommendations
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: rhTSH, Thyroid Size, and Radioiodine Therapy in Benign Goiter
Status: COMPLETED
Conditions: Benign Nontoxic and Toxic Goiter|Graves' Disease
Interventions: DRUG: Recombinant human thyrotropin (Thyrogen)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Mulligan Sustained Natural Apophyseal Glides Versus McKenzie Method in Patients With Non-Specific Chronic Low Back Pain
Status: COMPLETED
Conditions: Low Back Pain
Interventions: OTHER: Mulligan Sustained Natural Apophyseal Glide (SNAG)|OTHER: McKenzie Method|OTHER: Conventional Physical Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Open-Label Phase 1/2 Study of VELCADE for Injection in Patients With Light-chain (AL)-Amyloidosis
Status: COMPLETED
Conditions: Amyloidosis
Interventions: DRUG: VELCADE
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Inflammatory and Healing Profile After Root Coverage With Emdogain®
Status: COMPLETED
Conditions: Gingival Recession
Interventions: PROCEDURE: Microsurgery technique for root coverage|BIOLOGICAL: Microsurgery technique for root coverage associated to EMD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: MagnetisMM-4: Umbrella Study of Elranatamab (PF-06863135) in Combination With Anti-Cancer Treatments in Multiple Myeloma
Status: RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: Elranatamab + Nirogacestat|DRUG: Elranatamab + lenalidomide + dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Efficacy and Safety of HGP2102 in Essential Hypertension Patients
Status: NOT_YET_RECRUITING
Conditions: Hypertension
Interventions: DRUG: HGP2102-1|DRUG: HGP2102-2|DRUG: RLD2209-1|DRUG: RLD2209-2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: PROCRIT Extended Dosing For Maintenance of Hemoglobin in Pre-Dialysis CKD Patients
Status: COMPLETED
Conditions: Anemia|Renal Diseases
Interventions: DRUG: epoetin alfa|DRUG: epoetin alfa|DRUG: epoetin alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Metformin on Blood Vessel Structure and Function
Status: COMPLETED
Conditions: Obesity|Hypertension|Hypercholesterolemia|Hyperglycemia
Interventions: DRUG: Metformin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT