pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Point of Care Diagnosis of Vaginal Infections
Status: NOT_YET_RECRUITING
Conditions: Vaginitis|Bacterial Vaginosis|Yeast Vaginitis|Trichomonas Vaginitis
Interventions: DIAGNOSTIC_TEST: Xpert® Xpress MVP test|DIAGNOSTIC_TEST: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of Ciclesonide Nasal Spray in Patients 18 Years and Older With Seasonal Allergic Rhinitis (BY9010/M1-413)
Status: COMPLETED
Conditions: Rhinitis, Allergic, Seasonal|Hay Fever
Interventions: DRUG: Ciclesonide Nasal Spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Standard Open Surgery Versus Endovascular Repair of Abdominal Aortic Aneurysm (AAA)
Status: COMPLETED
Conditions: Aortic Aneurysm
Interventions: PROCEDURE: Endovascular Repair|PROCEDURE: Standard Open Repair
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mocetinostat (MGCD0103) Plus Brentuximab Vedotin (SGN-35) in Patients With Relapsed or Refractory Hodgkin Lymphoma
Status: COMPLETED
Conditions: Hodgkin Lymphoma
Interventions: DRUG: Mocetinostat Plus Brentuximab Vedotin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Perioperative FOLFIRI VS Adjuvant FOLFIRI in Resectable Advanced CRC Failed to Oxaliplatin
Status: RECRUITING
Conditions: Colorectal Neoplasms|Effects of Chemotherapy|Surgery|Metastasis|Local Neoplasm Recurrence
Interventions: DRUG: Irinotecan|DRUG: 5-fluorouracil|RADIATION: Local radiotherapy|PROCEDURE: R0 resection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bintrafusp Alfa and Stereotactic Body Radiation Therapy for the Treatment of Recurrent or Second Primary Head and Neck Squamous Cell Cancer
Status: TERMINATED
Conditions: Recurrent Head and Neck Squamous Cell Carcinoma|Second Primary Squamous Cell Carcinoma of the Head and Neck
Interventions: DRUG: Bintrafusp Alfa|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration|RADIATION: Stereotactic Body Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Diabetes Specialist Nurse as Delegated Main Care Provider for Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: PROCEDURE: Treated and educated by nurses specialized in diabetes.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dexmedetomidine for Analgosedation to Newborn Infants During Neonatal Intensive Care
Status: WITHDRAWN
Conditions: Intensive Care, Neonatal|Analgesia|Hypnotics and Sedatives
Interventions: DRUG: dexmedetomidine
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Crossover Study on the Blinding Effect of a New Pragmatic Placebo Needle
Status: COMPLETED
Conditions: Device Ineffective
Interventions: DEVICE: real needle- placebo needle|DEVICE: placebo needle - real needle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Randomized, Crossover Safety and Pharmacokinetics Study of PT010
Status: COMPLETED
Conditions: COPD
Interventions: DRUG: PT010 Dose 1|DRUG: PT010 Dose 2|DRUG: Placebo MDI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Laser vs Bevacizumab Injection Alone in Treatment of Diabetic Macular Edema
Status: WITHDRAWN
Conditions: Diabetic Macular Edema
Interventions: DRUG: bevacizumab|DEVICE: PASCAL Endpoint Management (EpM) laser treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Sequenced Behavioral and Medication Intervention for Cocaine Dependence
Status: COMPLETED
Conditions: Cocaine Dependence
Interventions: BEHAVIORAL: Computer-assisted behavior therapy|DRUG: Mixed-Amphetamine Salts- Extended Release (MAS-ER)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Interaction Study of Clopidogrel 300/75 mg Given Alone or Concomitantly With Omeprazole 80 mg in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: clopidogrel|DRUG: placebo|DRUG: omeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Virtual Reality Assisted CBT for Social Difficulties: a Feasibility Study in Early Intervention for Psychosis Services
Status: COMPLETED
Conditions: Psychosis|Social Behavior|Paranoia|Social Anxiety
Interventions: OTHER: Virtual reality assisted CBT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility of Conducting a Clinical Trial Assessing Efficacy of Lactate as Adjunctive Therapy in Patients With Major Depressive Disorder
Status: NOT_YET_RECRUITING
Conditions: Major Depressive Disorder
Interventions: DRUG: Sodium lactate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Enzalutamide/Leuprolide +/- Abiraterone/Pred in Prostate
Status: COMPLETED
Conditions: Prostate Adenocarcinoma|Prostate Cancer|High Risk Prostate Cancer
Interventions: DRUG: Enzalutamide|DRUG: Abiraterone Acetate|DRUG: Prednisone|DRUG: Leuprolide Acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Microneedling With Topical Preparations in the Treatment of Atrophic Post-acne Scars
Status: NOT_YET_RECRUITING
Conditions: Acne Scars - Mixed Atrophic and Hypertrophic
Interventions: DRUG: microneedling with topical glycolic acid 35%.|DRUG: microneedling with topical human insulin solution.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Incidence and Economic Burden of Clostridium Difficile Infections (CDI) in the German Health Care System (IBIS)
Status: UNKNOWN
Conditions: Clostridium Difficile Infection|Clostridium Difficile Diarrhea
Interventions: OTHER: Treatment of CDI
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Role of Vitamin K on Knee Osteoarthritis Outcomes
Status: NOT_YET_RECRUITING
Conditions: Osteo Arthritis Knee
Interventions: DRUG: Vitamin K1 500 µg|DRUG: K1 1000 µg|DRUG: Vitamin K2 (MK-7) 300 µg|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Trial for Men With Metastatic Prostatic Adenocarcinoma
Status: COMPLETED
Conditions: Metastatic Prostatic Adenocarcinoma
Interventions: DRUG: Opdivo Injectable Product|DRUG: Yervoy Injectable Product|DRUG: Cytoxan|PROCEDURE: Cryosurgical freezing (cryosurgery)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Parent-mediated and Telehealth Intervention for Children With Autism Spectrum Disorder
Status: RECRUITING
Conditions: Autism Spectrum Disorder
Interventions: BEHAVIORAL: Telehealth Early Intervention Program (TEIP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate The Safety, Tolerability, And Immune Response of a Range of Doses of mRNA-1769 Compared With Placebo in Healthy Participants From ≥18 Years of Age to <50 Years of Age
Status: ACTIVE_NOT_RECRUITING
Conditions: Smallpox|Mpox
Interventions: BIOLOGICAL: mRNA-1769|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Can INSTI-associated Weight Gain be Halted or Reversed With a Switch to Doravirine/Lamivudine/Tenofovir DF?
Status: TERMINATED
Conditions: Hiv|Weight Gain
Interventions: DRUG: DOR/3TC/TDF
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Smoking Cessation for Veterans With Severe and Persistent Mental Illness
Status: COMPLETED
Conditions: Schizoaffective Disorder|Schizophrenia|Affective Psychosis, Bipolar|Affective Disorders, Psychotic
Interventions: BEHAVIORAL: BTSCS|BEHAVIORAL: StSST
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Mindfulness-based Psychoeducation Program on Young People
Status: COMPLETED
Conditions: Stress|Emotional Intelligence|Nursing|Psychological Well-being|Mindfulness
Interventions: OTHER: Mindfulness-based psychoeducation program|OTHER: ongoing life
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: External Mastalgia-oil Versus Oral Tamoxifen in Premenopausal Women With Severe Mastalgia
Status: NOT_YET_RECRUITING
Conditions: Mastalgia
Interventions: DRUG: mastalgia-oil, tamoxifen placebo|DRUG: mastalgia-oil placebo, tamoxifen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: А Dose-finding Study to Assess the Efficacy and Safety of CD-008-0045 in Patients With Generalized Anxiety Disorder
Status: COMPLETED
Conditions: Anxiety Disorder Generalized
Interventions: DRUG: CD-008-0045|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability of LIM-0705 in Healthy Male Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: LIM-0705 and tacrolimus|DRUG: LIM-0705 and tacrolimus|DRUG: Placebo LIM-0705 and tacrolimus|DRUG: Drug LIM-0705 and placebo tacrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Erdafitinib Versus Investigator Choice of Intravesical Chemotherapy in Participants Who Received Bacillus Calmette-Guérin (BCG) and Recurred With High Risk Non-Muscle-Invasive Bladder Cancer (NMIBC)
Status: ACTIVE_NOT_RECRUITING
Conditions: Urinary Bladder Neoplasms
Interventions: DRUG: Erdafitinib|DRUG: Investigator Choice (Gemcitabine)|DRUG: Investigator Choice (Mitomycin C)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gemtuzumab Ozogamicin in Combination With A-HAM in Refractory AML (GO-A-HAM)
Status: COMPLETED
Conditions: Leukemia, Myeloid, Acute
Interventions: DRUG: Cytarabine|DRUG: Mitoxantrone|DRUG: Gemtuzumab Ozogamicin|DRUG: All-trans-Retinoid Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy-safety Study of Sublingual Immunotherapy With Depigmented-polymerized Pollen Extracts to Treat Rhinoconjunctivitis
Status: COMPLETED
Conditions: Allergic Rhinoconjunctivitis
Interventions: BIOLOGICAL: Grass pollen allergenic extract (L. perenne-C. dactylon )|BIOLOGICAL: Grass pollen allergenic extract (L. perenne-C. dactylon )|BIOLOGICAL: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Food on the Pharmacokinetics of Tesetaxel 10 mg Capsules
Status: COMPLETED
Conditions: Solid Tumors
Interventions: DRUG: Tesetaxel 10 mg with and then without food|DRUG: Tesetaxel 10 mg without and then with food
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: The Effect of Lactoferrin and Dosing Regimen on Iron Absorption From a Maize-based Porridge in Kenyan Infants
Status: COMPLETED
Conditions: Iron-deficiency
Interventions: DIETARY_SUPPLEMENT: apo-Lactoferrin|DIETARY_SUPPLEMENT: holo-Lactoferrin|DIETARY_SUPPLEMENT: FeSO4|DIETARY_SUPPLEMENT: 1. FeSO4|DIETARY_SUPPLEMENT: FeSO4 after 1 day break|DIETARY_SUPPLEMENT: FeSO4 after 2 day break
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Open-label Extension Study of the Phase 3 VRX-RET-E22-301 Double-Blind Trial
Status: COMPLETED
Conditions: Epilepsy
Interventions: DRUG: Ezogabine: USAN Retigabine (International Nonproprietary Name)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High Precision Imaging of Prostate Specific Membrane Antigen for Personalized Treatment in Prostate Cancer
Status: RECRUITING
Conditions: Prostate Cancer
Interventions: OTHER: 68Ga-PSMA (HBED-CC) PET
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of Quality of Life in Freeman-Sheldon Syndrome and Related Conditions
Status: TERMINATED
Conditions: Arthrogryposis|Craniofacial Abnormalities|Posttraumatic Stress Disorder|Depressive Disorder
Interventions: OTHER: PTSD Checklist-Specific|OTHER: Modified Flanagan Quality of Life Scale|OTHER: Center for Epidemiologic Studies Depression Scale|OTHER: Functional Enquiry Form|OTHER: Strength, Joint ROM, Girth and Length Measurements|OTHER: Study Physical Examination|OTHER: PTSD, Depression, and FSS-Focused Examination|OTHER: Freeman-Sheldon Specific Quality of Life Survey|OTHER: Lactate, Glucose, and Adenosine Triphosphate Blood Levels
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Impact of DuoTherm on Acute Opioid Use and Low Back Pain
Status: ACTIVE_NOT_RECRUITING
Conditions: Opioid Use|Low Back Pain
Interventions: DEVICE: DuoTherm|DEVICE: TENS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Safety and Immunogenicity of GSK Biologicals' Seasonal Influenza Vaccine in Adults
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Quadrivalent seasonal influenza vaccine GSK2282512A|BIOLOGICAL: FluLavalTM-VB|BIOLOGICAL: FluLavalTM-YB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluating Dynamic Arterial Elastance in Septic Shock Patients.
Status: NOT_YET_RECRUITING
Conditions: Septic Shock
Interventions: PROCEDURE: EaDyn Weaning Arm:|PROCEDURE: PAM Weaning Arm:
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Registry to Investigate the Efficacy and Safety of VenaBlock VeIn SEaling System for VaRicose Veins in SingApore
Status: UNKNOWN
Conditions: Varicose Veins|Venous Reflux|Chronic Venous Insufficiency
Interventions: OTHER: Questionnaires
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Post Bariatric Closed Loop Glucagon Trial
Status: COMPLETED
Conditions: Hypoglycemia
Interventions: DEVICE: Glucagon-only bionic pancreas - glucagon|DEVICE: Glucagon-only bionic pancreas - placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Buprenorphine for Treatment Resistant Depression
Status: COMPLETED
Conditions: Depression|Depressive Disorder|Depressive Disorder, Major
Interventions: DRUG: Buprenorphine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Megadose Vitamin C in Severe and Critical Ill COVID-19 Patients.
Status: RECRUITING
Conditions: Vitamin C|COVID-19 Pneumonia
Interventions: DRUG: Vitamin C|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Effect of a Six Week Intensified Pharmacological Treatment for Schizophrenia Compared to Treatment as Usual in Subjects Who Had a First-time Treatment Failure on Their First-line Treatment.
Status: RECRUITING
Conditions: Schizophrenia and Related Disorders|Early Treatment-Resistance
Interventions: DRUG: Clozapine|DRUG: Second-line Antipsychotics (treatment as usual)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Irritation Potential of GSK2894512 Cream on Skin in Healthy Subjects
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: GSK2894512 cream|DRUG: Vehicle cream|DRUG: Positive control|DRUG: Negative control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy Of Magnesium In Radicular Pain When Added To Local Anesthetics And Steroids In Transforaminal Epidural Injection
Status: UNKNOWN
Conditions: Neuropathy|Pain
Interventions: DRUG: magnesium|DRUG: Methylprednisolone|DRUG: Bupivacaine Hydrochloride|DRUG: saline 0.9%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Is Iron Deficiency the Cause of Anemia Among Women in Cambodia?
Status: COMPLETED
Conditions: Anemia|Iron Deficiency|Hemoglobin Disorder|Infection|Inflammation
Interventions: DIETARY_SUPPLEMENT: Multiple micronutrients|DIETARY_SUPPLEMENT: Iron|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effect of Epidural Fentanyl on Immune Function
Status: UNKNOWN
Conditions: Malignancy
Interventions: DRUG: epidural fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of ATG-010 in Combination With Lenalidomide and Rituximab (R2) in Adults With DLBCL and iNHL
Status: RECRUITING
Conditions: Diffuse Large B-cell Lymphoma|Indolent Non-Hodgkin Lymphoma
Interventions: DRUG: ATG-010|DRUG: Lenalidomide|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Safety and Dosing Effect on SMN Levels of Valproic Acid (VPA) in Patients With Spinal Muscular Atrophy
Status: COMPLETED
Conditions: Spinal Muscular Atrophy
Interventions: DRUG: Valproic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparison of a Fully Covered Self-expandable Metal Stent With an External Anchoring Plastic Stent and Uncovered Stent
Status: RECRUITING
Conditions: Malignant Biliary Obstruction
Interventions: DEVICE: fully covered self-expandable metal stent with an anchoring external plastic stent|DEVICE: uncovered self-expandable metal stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical and Urodynamic Effects of Minimally Laser (IncontiLaseTM) Procedure for Female Stress Urinary Incontinence
Status: COMPLETED
Conditions: Stress Urinary Incontinence
Interventions: PROCEDURE: the IncontiLaseTM procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tack Optimized Balloon Angioplasty Below the Knee (TOBA - BTK) Study
Status: COMPLETED
Conditions: Critical Limb Ischemia|Peripheral Artery Disease
Interventions: DEVICE: Tack-It Endovascular System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of CBD-Rich Oil on Aversive Memory Reconsolidation
Status: UNKNOWN
Conditions: Anxiety and Fear
Interventions: BEHAVIORAL: Interoceptive Aversive Memory Reactivation|DIETARY_SUPPLEMENT: Cannabidiol (CBD)-Rich Broad Spectrum Hemp Extract Oil|DIETARY_SUPPLEMENT: Placebo Oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Effect of Long Round Needle
Status: COMPLETED
Conditions: Cervical Spondylotic Radiculopathy
Interventions: PROCEDURE: Filiform needle|PROCEDURE: Long round needle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Brief Cognitive Behavioral Therapy for Military Populations
Status: COMPLETED
Conditions: Suicide|Suicidal Ideation
Interventions: BEHAVIORAL: Brief Cognitive Behavioral Therapy (BCBT)|BEHAVIORAL: Treatment As Usual (TAU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Follow-on Protocol of Pitavastatin Versus Simvastatin in Patients With Hypercholesterolemia or Dyslipidemia and Coronary Heart Disease Risk Factors
Status: COMPLETED
Conditions: Hypercholesterolemia|Dyslipidemia|Coronary Heart Disease
Interventions: DRUG: pitavastatin|DRUG: simvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study Using Adipose-derived Stem Cells for Diabetic Foot
Status: UNKNOWN
Conditions: Peripheral Vascular Disease|Ischemia|Diabetic Foot
Interventions: BIOLOGICAL: Adipose-derived stem cell|BIOLOGICAL: saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dabrafenib and Trametinib Before and After Surgery in Treating Patients With Stage IIIB-C Melanoma With BRAF V600 Mutation
Status: ACTIVE_NOT_RECRUITING
Conditions: Stage IIIB Cutaneous Melanoma AJCC v7|Stage IIIC Cutaneous Melanoma AJCC v7
Interventions: DRUG: Dabrafenib|OTHER: Laboratory Biomarker Analysis|PROCEDURE: Therapeutic Conventional Surgery|DRUG: Trametinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SHR-1210 Plus Apatinib in Patients With Hepatocellular Carcinoma After Surgery
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: SHR-1210|DRUG: apatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Microbiome and Malnutrition in Pregnancy (MMiP)
Status: ACTIVE_NOT_RECRUITING
Conditions: Weight Gain, Pregnancy|Microbial Colonization|Pregnancy Related|Pregnancy Loss|Pregnancy Complications|Pregnancy; Parasitic Disease|Parasitic Disease|Microbial Disease|Infant Malnutrition|Malnutrition|Malnutrition in Pregnancy|Breastfeeding
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of IMC-1121B in Patients With Tumors That Have Not Responded to Therapy
Status: COMPLETED
Conditions: Advanced Solid Tumors
Interventions: BIOLOGICAL: IMC-1121B|BIOLOGICAL: 1121B|BIOLOGICAL: 1121B|BIOLOGICAL: 1121B|BIOLOGICAL: 1121B|BIOLOGICAL: 1121B|BIOLOGICAL: 1121B
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Combined Er:YAG And Nd:YAG Laser Protocol For Treatment Of Peri-Implantitis
Status: RECRUITING
Conditions: Peri-Implantitis
Interventions: DEVICE: Lightwalker Laser (Fotona)|OTHER: standard
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Towards Predicting the Analgesic Response to Ibuprofen Following Third-molar Extraction
Status: COMPLETED
Conditions: Impacted Third Molar Tooth|Pain, Acute
Interventions: DRUG: Ibuprofen|DRUG: Acetaminophen|DRUG: Placebo|DRUG: Oxycodone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: The Influence of Perioperative Administration of Dexmedetomidine on Inflammation Response and Postoperative Recovery in Patients Undergoing Robot or Laparoscopic Assisted Gastrectomy
Status: COMPLETED
Conditions: Gastric Cancer|Gastrostomy
Interventions: DRUG: dexmedetomidine|DRUG: saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Efficacy of AST-120 in Patients With GERD Who Continue to be Symptomatic on a Standard Dose of PPI
Status: TERMINATED
Conditions: Gastroesophageal Reflux Disease (GERD)
Interventions: DRUG: AST-120|DRUG: Celphere CP-305
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Washcloths Effectiveness in Preventing Pressure Ulcers
Status: COMPLETED
Conditions: Pressure Ulcer|Skin Ulcer
Interventions: PROCEDURE: 3-in-1 perineal care washcloths
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Neuronal Correlates of Neurexan® Action in Mildly to Moderately Stressed Probands
Status: COMPLETED
Conditions: Acute Stress Reaction
Interventions: DRUG: Neurexan®|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Nebivolol in Hypertensive Patients With Coronary Artery Disease
Status: COMPLETED
Conditions: Hypertension|Coronary Artery Disease
Interventions: DRUG: Nebivolol|DRUG: Carvedilol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Goal Directed Fluid Therapy and Postoperative Ileus
Status: COMPLETED
Conditions: Postoperative Ileus
Interventions: PROCEDURE: Goal Directed Fluid Therapy (GDFT)-Esophageal doppler guided|OTHER: Standard fluid therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Study of the Safety, Pharmacokinetics, Pharmacodynamics, and Immunogenicity of Anti-Abeta (MABT5102A) in Patients With Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: anti-Abeta|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dose Reduction of Postoperative Radiation for Soft Tissue Sarcoma of the Arms and Legs
Status: RECRUITING
Conditions: Soft Tissue Sarcoma
Interventions: RADIATION: Intensity-modulated radiation therapy (IMRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Learn How the Drug Aflibercept Works in in Japanese Patients With Increased Eye Pressure That is Caused by New Blood Vessels Growing in the Eye (Neovascular Glaucoma or NVG). Safety of the Drug and Patients' Tolerability of the Drug Injection is Also Studied
Status: COMPLETED
Conditions: Glaucoma, Neovascular
Interventions: DRUG: Aflibercept (EYLEA, BAY86-5321)|DRUG: Topical IOP-lowering drugs
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: New Method for Real-time Detection of Tissue Ischemia (ISCALERT)
Status: COMPLETED
Conditions: Ischemia|Blood Circulation Disorder|Carbon Dioxide|Biosensing Techniques
Interventions: DEVICE: IscAlert|DEVICE: IscAlert 72h
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Alpha/Beta TCD HCT in Patients With Inherited BMF Disorders
Status: RECRUITING
Conditions: Fanconi Anemia|Severe Aplastic Anemia|Myelodysplastic Syndromes|T Cell Receptor Alpha/Beta Depletion|Telomere Biology Disorder|Bone Marrow Failure|Dyskeratosis Congenita
Interventions: DRUG: Total Body Irradiation (TBI) (Plan 1)|DRUG: Cyclophosphamide (CY) (Plan 1)|DRUG: Fludarabine (FLU)|DRUG: Methylprednisolone (MP)|DEVICE: Donor mobilized PBSC infusion|DRUG: G-CSF|DRUG: Cyclophosphamide (CY) (Plan 2)|DRUG: Rituximab|DRUG: Busulfan|DRUG: Alemtuzumab|DRUG: Melphalan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Ultrasound-Guided Rhomboid Intercostal Block Versus Serratus Plane Block in Mastectomy.
Status: UNKNOWN
Conditions: Mastectomy|Rhomboid Intercostal Block|Serratus Plane Block
Interventions: OTHER: Serratus Plane Block (SPB)|OTHER: Rhomboid intercostal nerve block (RIB)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Lopinavir (LPV) Dose Reduction
Status: COMPLETED
Conditions: HIV-1 Infections
Interventions: DRUG: Generic LPV/r and Aluvia (pharmacokinetics)|DRUG: Aluvia and Generic LPV/r (pharmacokinetics)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Active Screening of Latent TB Infection, Treatment and Long Term Follow-up in Prison
Status: COMPLETED
Conditions: Tuberculosis
Interventions: DRUG: isoniazid , randomized, open label|DRUG: rifampin, randomized, open label
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Simvastatin Treatment to Improve Patient-reported Outcomes in Patients With Chronic Pancreatitis
Status: NOT_YET_RECRUITING
Conditions: Recurrent Acute Pancreatitis|Chronic Pancreatitis
Interventions: DRUG: Simvastatin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Efficacy and Safety of SKI3246 in Subjects With Non-Constipation Irritable Bowel Syndrome
Status: COMPLETED
Conditions: Non-constipation Irritable Bowel Syndrome
Interventions: DRUG: SKI3246 Low Dose|DRUG: SKI3246 High Dose|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Iron Substitution After Upper Gastro-Intestinal Bleeding
Status: COMPLETED
Conditions: Gastrointestinal Hemorrhage|Anemia
Interventions: DRUG: ferricarboxymaltose|DRUG: Ferrosulfate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Increasing Decision Quality for Men With Lower Urinary Tract Symptoms
Status: COMPLETED
Conditions: Patient Engagement|Patient Preference
Interventions: BEHAVIORAL: Physicians trained in shared decision making|BEHAVIORAL: Physicians were not trained in shared decision making
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study of the Efficacy and Tolerability of Pancrelipase Microtablet (MT) Capsules for the Treatment of Cystic Fibrosis-dependent Exocrine Pancreatic Insufficiency
Status: COMPLETED
Conditions: Exocrine Pancreatic Insufficiency|Steatorrhea|Malabsorption Syndromes|Cystic Fibrosis
Interventions: DRUG: Pancrease MT 10.5, or MT 21|DRUG: Placebo for Pancrease MT 10.5 or MT 21
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fluorine F 18 Sodium Fluoride Positron Emission Tomography in Evaluating Response to Dasatinib in Patients With Prostate Cancer and Bone Metastases
Status: COMPLETED
Conditions: Hormone-Resistant Prostate Cancer|Metastatic Malignant Neoplasm in the Bone|Recurrent Prostate Carcinoma|Stage IV Prostate Cancer
Interventions: RADIATION: Fluorine F 18 Sodium Fluoride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Combined Oral Vitamin D and UVB Versus UVB Alone in Treatment of Psoriasis Vulgaris
Status: UNKNOWN
Conditions: Psoriasis Vulgaris
Interventions: DRUG: oral vitamin D
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Project MATLINK: Development and Evaluation of a Screening, Brief Intervention, & Referral to Treatment (SBIRT) Program for Opioid Dependent Prisoners and Probationers Transitioning to the Community
Status: ACTIVE_NOT_RECRUITING
Conditions: Opioid-use Disorder|HIV Infections|Tuberculosis|Hepatitis C|Hepatitis B|Depression|Syphilis
Interventions: BEHAVIORAL: SBIRT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effect of Bosentan on Skin Fibrosis in Patients With Systemic Sclerosis
Status: COMPLETED
Conditions: Systemic Scleroderma|Skin Fibrosis|Hand Functionality
Interventions: DRUG: Bosentan (Tracleer)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Patient Satisfaction and Peri-Implant Tissue Success of Hybrid Ceramic Versus E-Max Superstructures
Status: UNKNOWN
Conditions: Prosthesis Survival
Interventions: OTHER: Crystal Ultra|OTHER: All ceramic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Trial of Osteoporosis Intervention Strategies in Hip Fracture Patients
Status: COMPLETED
Conditions: Osteoporosis|Hip Fracture
Interventions: BEHAVIORAL: Allied health professional-run osteoporosis service ("case-management")
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Effects of Pioglitazone in Calcific Aortic Valve Disease
Status: NOT_YET_RECRUITING
Conditions: Calcification of Aortic Valve|Aortic Valve Stenosis
Interventions: DRUG: Drug: Pioglitazone Oral Tablet|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Bioequivalence of Levamlodipine Besylate Tablets in Healthy Chinese Subjects
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: Amlodipine 10 mg|DRUG: Levamlodipine 5 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intermittent Vibrational Force and Orthodontic Tooth Movement
Status: COMPLETED
Conditions: Dental Crowding|Vibrational Force|Fixed Orthodontic Appliances
Interventions: DEVICE: AcceleDent vibrational device|DEVICE: Sham AcceleDent device|OTHER: Fixed appliance only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Customized Choice of Oral P2Y12 Receptor Blocker
Status: UNKNOWN
Conditions: Acute Coronary Syndrome|Coronary Angioplasty
Interventions: DRUG: Oral P2Y12 receptor blocker|DRUG: Customized choice for the oral P2Y12 receptor blocker
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nicotine Receptor Density & Response to Nicotine Patch: Pt 2 Extended Treatment
Status: COMPLETED
Conditions: Smoking Cessation|Schizophrenia
Interventions: DRUG: Combination Bupropion + NRTs|OTHER: Extended Treatment|OTHER: Home Visits & Calls|DRUG: Monotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Acupuncture on the Gait Disturbance and Hemodynamic Changes in the Prefrontal Cortex
Status: NOT_YET_RECRUITING
Conditions: Alzheimer Disease
Interventions: PROCEDURE: Acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: IOP Fluctuations in Patients With Sleep Apnea With or Without Primary Open Angle Glaucoma Using Positive Airway Pressure
Status: COMPLETED
Conditions: Sleep Apnea, Obstructive|Primary Open-angle Glaucoma
Interventions: DEVICE: SENSIMED Triggerfish®
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Neurofunctional and Neurochemical Markers of Treatment Response in Bipolar Disorder
Status: UNKNOWN
Conditions: Bipolar I Disorder
Interventions: DRUG: lithium|DRUG: Lithium
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Alternating Cycles of Carboplatin/Gemcitabine and Carboplatin/Taxol for Advanced Stage NSCLC
Status: COMPLETED
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: carboplatin/gemcitabine, carboplatin/taxol
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Combination Therapy of Carboplatin -Gemcitabine Plus Bevacizumab Beyond Progression in Patients With Locally Advanced and/or Metastatic Non-small Cell Lung Cancer (NSCLC) Who Have Not Received Prior Systemic Therapy
Status: COMPLETED
Conditions: Locally Advanced Non-Small Cell Lung Cancer|NSCLC
Interventions: DRUG: Paclitaxel, Carboplatin and Bevacizumab,Erlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of VieScope vs. Macintosh Laryngoscope for Intubation in Level Cpersonal Protective Equipment Conditions
Status: COMPLETED
Conditions: Tracheal Intubation|Infection|Projection
Interventions: DEVICE: The standard Macintosh laryngoscope|DEVICE: The Vie Scope laryngoscope
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Collaborative Model of Care Between Orthopaedics and Allied Healthcare Professionals Trial (CONnACT)
Status: UNKNOWN
Conditions: Osteoarthritis
Interventions: OTHER: Multidisciplinary Community Program|OTHER: Current model of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Non-invasive Repetitive Paraorbital Alternating Current Stimulation Therapy for Aphasia
Status: TERMINATED
Conditions: Aphasia
Interventions: DEVICE: rtACS stimulation (Verum condition)|DEVICE: placebo condition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Parallel-Arm Study to Compare AD109 to Placebo With Patients With OSA (SynAIRgy Study)
Status: RECRUITING
Conditions: OSA
Interventions: DRUG: AD109|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial With Bupivacaine Lozenges as Local Anaesthesia Under Upper Gastrointestinal Endoscopy
Status: COMPLETED
Conditions: Application Site Discomfort
Interventions: DRUG: Xylocain, cutaneous spray, solution|DRUG: Bupivacaine lozenge
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Prospective, Randomized, Multinational, Multicenter, Double-blind, Placebo and Active Controlled Trial in 4 Parallel-groups of Patients Suffering From Seasonal Allergic Rhinitis
Status: COMPLETED
Conditions: Seasonal Allergic Rhinitis
Interventions: DRUG: Mometasone|DRUG: Azelastine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Vitamin D in Pediatric Asthma: a Randomized Controlled Open-label Pilot Trial
Status: UNKNOWN
Conditions: Asthma|Vitamin D Deficiency
Interventions: DRUG: Vitamin D2 + vitamin D3|DRUG: Vitamin D3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Open-label Study for Participants Who Are Non-responders at the End of Treatment Assessment on the VRDN-001-101 and VRDN-001-301 Pivotal Studies
Status: RECRUITING
Conditions: Thyroid Eye Disease
Interventions: DRUG: Intervention/Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Impact of Breastfeeding Education on Breastfeeding Behavior and the Use of Traditional Practices
Status: COMPLETED
Conditions: Breastfeeding|Breasfeeding Traditional Practices|Post Procedural Discharge
Interventions: BEHAVIORAL: Breastfeeding Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: UCMSCs as Treatment for Patients With Acute Ischemic Stroke (Stroke Neuroncell-EX)
Status: RECRUITING
Conditions: Acute Ischemic Stroke
Interventions: BIOLOGICAL: Neuroncell-EX|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Perioperative Lung Protective Strategies on the Occurrence of Postoperative Pulmonary Complications in Patients Undergoing Lumbar Spinal Surgery in the Prone Position
Status: COMPLETED
Conditions: Pulmonary Complications
Interventions: OTHER: Conventional ventilation|OTHER: Protective lung ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: First-in-man Dose Escalation Study of BAY2010112 in Patients With Prostate Cancer
Status: COMPLETED
Conditions: Prostatic Neoplasms
Interventions: BIOLOGICAL: BAY2010112|BIOLOGICAL: BAY2010112
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ILMA Fastrach Versus I-gel for Fiberoptic Tracheal Intubation
Status: COMPLETED
Conditions: Tracheal Intubation
Interventions: DEVICE: i-gel|DEVICE: ILMA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Prevention of Lipoatrophy in Patients Treated With Lopinavir/Ritonavir in Monotherapy Versus ZDV + 3TC + ABC
Status: COMPLETED
Conditions: HIV Infection|HIV Infections
Interventions: DRUG: AZT+3TC+ABV (Trizivir)|DRUG: Switching to LPV/r monotherapy (Kaletra)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy, Safety, and Tolerability of Levomilnacipran ER in Pediatric Patients (7-17 Years) With Major Depressive Disorder
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: Levomilnacipran ER|DRUG: Fluoxetine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Trial of Tapering Antipsychotics for Patients in Remitted Psychosis Co-administering With N-Acetylcysteine
Status: NOT_YET_RECRUITING
Conditions: Psychosis
Interventions: DRUG: N-Acetylcysteine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Host Dysregulation-Driven Sepsis Prediction Model
Status: NOT_YET_RECRUITING
Conditions: Sepsis
Interventions: OTHER: Tumor Necrosis Factor|OTHER: Interleukin-1β|OTHER: Interleukin-12|OTHER: Interleukin-18|OTHER: Complement C3|OTHER: Complement C5
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Imatinib Mesylate in Treating Patients With Locally Advanced or Metastatic Dermatofibrosarcoma Protuberans or Giant Cell Fibroblastoma
Status: COMPLETED
Conditions: Sarcoma
Interventions: DRUG: imatinib mesylate|PROCEDURE: conventional surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT