pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Study of Milvexian in Participants After an Acute Ischemic Stroke or High-Risk Transient Ischemic Attack- LIBREXIA-STROKE
Status: RECRUITING
Conditions: Ischemic Stroke; Ischemic Attack, Transient
Interventions: DRUG: Milvexian|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: pBFS-guided iTBS Over the Superior Temporal Gyrus for Aphasia After Ischemic Stroke
Status: NOT_YET_RECRUITING
Conditions: Stroke, Ischemic|Aphasia
Interventions: DEVICE: active intermittent Theta Burst Stimulation|DEVICE: sham intermittent Theta Burst Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Virtual Reality's Role in See&Treat Hysteroscopy
Status: COMPLETED
Conditions: Endometrial Cancer|Endometrial Diseases|Myoma;Uterus|Endometrial Hyperplasia
Interventions: DEVICE: Use of virtual reality during the hysteroscopic procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Efficacy of TKI258 in Relapsed or Refractory Multiple Myeloma Patients, Who Are With or Without t(4;14) Chromosomal Translocation
Status: COMPLETED
Conditions: Relapsed or Refractory Multiple Myeloma
Interventions: DRUG: TKI258
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Microparticle Enhanced Cytotoxic Transarterial Embolization Therapy in Hepatocellular Carcinoma
Status: COMPLETED
Conditions: Hepatocellular Carcinoma
Interventions: DEVICE: TANDEM™
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Using Positive Pressure Ventilation for Preoxygenation During Panendoscopy.
Status: COMPLETED
Conditions: ENT Cancer Screening
Interventions: DEVICE: positive pressure ventilation|PROCEDURE: Oxygenation with simple breathing mask
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pulmonary Suffusion in Controlling Minimal Residual Disease in Patients With Sarcoma or Colorectal Metastases
Status: RECRUITING
Conditions: Metastatic Bone Sarcoma|Metastatic Malignant Neoplasm in the Lung|Metastatic Soft Tissue Sarcoma|Metastatic Unresectable Sarcoma|Resectable Sarcoma|Colorectal Cancer
Interventions: DRUG: Cisplatin|PROCEDURE: Isolated Chemotherapeutic Lung Perfusion|PROCEDURE: Metastasectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Brentuximab Vedotin in Participants With Relapsed or Refractory Hodgkin Lymphoma
Status: COMPLETED
Conditions: Hodgkin Lymphoma
Interventions: DRUG: Brentuximab Vedotin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Self-education Program for Advanced Care Planning(RCT) for General Population
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: Videos about ACP|OTHER: Brochure about Life-Sustaining Treatment Act
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effect of Xolair on Airway Hyperresponsiveness
Status: UNKNOWN
Conditions: Allergic Asthma
Interventions: DRUG: Omalizumab|DRUG: Placebo for Omalizumab|DRUG: omalizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Tissue and Hematopoietic/Mesenchymal Stem Cell for Humanized Xenograft Studies in Melanoma and Squamous Head and Neck Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Malignant Melanoma|Head and Neck Cancer
Interventions: DRUG: Filgrastim
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Prospective Study of Conventional Bone Marrow Biopsy Versus Portomar(TM) Biopsy
Status: RECRUITING
Conditions: Hematologic Malignancy
Interventions: DEVICE: Portomar(TM) Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Impact of the Mandibular Advancement Device on Sleep Apnea During CPAP Withdrawal
Status: NOT_YET_RECRUITING
Conditions: Sleep Apnea, Obstructive|Endothelial Dysfunction
Interventions: DEVICE: Mandibular advancement device treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exercise is Medicine at Emory Seavey Internal Medicine Clinic
Status: COMPLETED
Conditions: Physical Activity
Interventions: BEHAVIORAL: App|BEHAVIORAL: Wearable Device|BEHAVIORAL: Automated Motivational Message|BEHAVIORAL: Personalized Motivational Message
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Nucleoid as an Adjuvant Therapy After Radiofrequency Ablation for Hepatocellular Carcinoma
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma|Liver Cancer
Interventions: PROCEDURE: RFA|DRUG: lamivudine or entecavir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Early Thienopyridine Treatment to Improve Primary PCI in Patients With Acute MI
Status: COMPLETED
Conditions: Myocardial Infarction|STEMI
Interventions: DRUG: Prasugrel|DRUG: Clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the 24-Hour Pulmonary Function Profile of Fluticasone Furoate (FF) /GW642444 (Vilanterol) (VI) Inhalation Powder 100/25mcg Once Daily Compared With Fluticasone Propionate/Salmeterol Inhalation Powder 250/50mcg Twice Daily in Subjects With Chronic Obstructive Pulmonary Disease
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Fluticasone Furoate 100mcg / GW642444 (vilanterol) 25mcg|DRUG: Fluticasone Propionate 250mcg/ salmeterol 50mcg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of PEG-Encapsulated Islet Allografts Implanted in Type I Diabetic Recipients
Status: TERMINATED
Conditions: Diabetes Mellitus, Type 1
Interventions: BIOLOGICAL: Allogeneic Cultured Islet Cells (human); Encapsulated
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of Apelin Levels on Postoperative Cognitive Disorders After Orthopedic Surgery in Elderlies (APOCOGNIT)
Status: COMPLETED
Conditions: Delirium
Interventions: OTHER: Determination of apelin and inflammatory cytokines|OTHER: Assessment of cognitive functions|OTHER: Liquid sampling cerebrospinal|OTHER: Postoperative delirium research|OTHER: Residual cognitive dysfunction research
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Endoscopic Drainage of Presumed Resectable pCCA Using an Intrahepatic Plastic Stent With Retrieval String
Status: RECRUITING
Conditions: Perihilar Cholangiocarcinoma
Interventions: DEVICE: Intrahepatic biliary stent with retrieval string
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single Site, Masked, Randomized, Controlled Study to Assess Efficacy of Osurdex as Adjunct to Avastin Compared With Avastin Alone in the Treatment of Patients With Macular Edema Due to Central or Branch Retinal Vein Occlusion
Status: COMPLETED
Conditions: Retinal Vein Occlusions
Interventions: DRUG: Avastin|DRUG: Osurdex|DRUG: Avastin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Effects of Allergic Rhinitis and Co-administration of Mometasone or Oxymetazoline on the Pharmacokinetics, Safety, and Tolerability of Intranasal Esketamine
Status: COMPLETED
Conditions: Allergic Rhinitis
Interventions: DRUG: Esketamine|DRUG: Mometasone|DRUG: Oxymetazoline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Dose Escalation Study of VX-708 in Healthy Participants
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: VX-708|DRUG: Itraconazole|DRUG: Midazolam|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Safety, Pharmacokinetics, and Pharmacodynamics of CHI-915 in Healthy Participants
Status: COMPLETED
Conditions: Healthy Adults
Interventions: DIETARY_SUPPLEMENT: THCv
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Airway Response to Repeat Allergen Challenge and the Effect of Ibuprofen in Mild Atopic Asthma
Status: COMPLETED
Conditions: Atopic Asthma
Interventions: DRUG: ibuprofen|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Randomized Controlled Trial of a Multicomponent Walking Aid Program for People With MS
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: BEHAVIORAL: ADSTEP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study to Evaluate the Safety and Immunogenicity of a Pandemic Influenza Vaccine in Adults Aged Between 18 and 60 Years
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: 4 adjuvanted pandemic influenza candidate vaccines|BIOLOGICAL: 4 non-adjuvanted pandemic influenza candidate vaccines
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: |Primary Purpose: PREVENTION
Clinical trial: Late-initiated Blood Flow Restricted Rehabilitation Exercises After Total Knee Replacement
Status: ENROLLING_BY_INVITATION
Conditions: Osteoarthritis, Knee|Arthropathy of Knee
Interventions: OTHER: Blood flow restricted low-load resistance exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EVALUATION OF THE SAFETY AND EFFICACY OF ADJUSTABLE CONTINENT THERAPY IN CHILDREN WITH SPINAL DYSRAPHISM.
Status: NOT_YET_RECRUITING
Conditions: Neurogenic Bladder Due to Spinal Dysraphism
Interventions: DEVICE: Implantation of ACT balloon, Uromedica (Irvine, CA, USA) periurethrally at the bladder neck
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Risk Enabled Therapy After Initiating Neoadjuvant Chemotherapy for Bladder Cancer (RETAIN)
Status: ACTIVE_NOT_RECRUITING
Conditions: Urothelial Carcinoma of the Bladder
Interventions: DRUG: Methotrexate|DRUG: Vinblastine|DRUG: Doxorubicin|DRUG: Cisplatin|RADIATION: Intensity modulated radiation therapy (IMRT)|PROCEDURE: Transurethral Resection of Bladder tumor|DRUG: 5-FU|DRUG: Mitomycin C
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: French Aquablation Clinical Investigation Using Waterjet Ablation Therapy for Endoscopic Resection of Prostate Tissue
Status: COMPLETED
Conditions: Benign Prostatic Hyperplasia (BPH)
Interventions: DEVICE: AQUABEAM System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: First-in-Human Study of NI006 in Patients With Amyloid Transthyretin Cardiomyopathy
Status: COMPLETED
Conditions: Amyloid Transthyretin Cardiomyopathy
Interventions: DRUG: NI006|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Oral Amantadine Versus Gabapentin to Attenuate the Response to Laryngoscopy and Tracheal Intubation
Status: COMPLETED
Conditions: Effect of Laryngoscopy and Tracheal Intubation
Interventions: OTHER: oral amantadine sulfate|DRUG: oral gabapentin|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of a High EPA Multinutrient Supplement on Negative Affect in Young Adults.
Status: RECRUITING
Conditions: Anxiety|Depression
Interventions: DIETARY_SUPPLEMENT: High-EPA multinutrient supplement.|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy Study of Dendritic Cell Vaccination in Patients With Acute Myeloid Leukemia in Remission
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Myeloid Leukemia
Interventions: BIOLOGICAL: DC vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Repetitive Transcranial Magnetic Stimulation on Neurological Recovery in Patients With Ischaemic Stroke
Status: NOT_YET_RECRUITING
Conditions: Stroke Ischemic
Interventions: DEVICE: rTMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Singapore INfra-Genicular Angioplasty With PAclitaxel-eluting Balloon for Critical Limb Ischaemia (SINGA-PACLI) Trial
Status: COMPLETED
Conditions: Peripheral Arterial Disease
Interventions: DEVICE: CB-PTA|DEVICE: DEB-PTA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Study of MORAb-004 in Patients With Solid Tumor (Study: MORAb-004-J081-103)
Status: COMPLETED
Conditions: Solid Tumor
Interventions: DRUG: MORAb-004
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 2a Study to Evaluate Safety and Explore Efficacy of J2H-1702 for NASH
Status: RECRUITING
Conditions: Non-alcoholic Steatohepatitis
Interventions: DRUG: J2H-1702|DRUG: J2H-1702|DRUG: J2H-1702|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Of Fluticasone Propionate/Salmeterol In Asthmatic Subjects
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: FP|DRUG: SFC|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Drug-coating Balloon Angioplasties for True Coronary Bifurcation Lesions
Status: ACTIVE_NOT_RECRUITING
Conditions: Coronary Artery Disease
Interventions: DEVICE: Drug-coating balloon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of the SonRtip Lead and Automatic AV-VV Optimization Algorithm in the PARADYM RF SonR CRT-D
Status: UNKNOWN
Conditions: Heart Failure NYHA Class III and Ambulatory IV
Interventions: DEVICE: PARADYM RF SONR|DEVICE: PARADYM RF SONR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tirofiban Intracoronary Bolus-only Versus Intravenous Bolus Plus Infusion in STEMI Patients
Status: COMPLETED
Conditions: Acute Myocardial Infarction
Interventions: DRUG: tirofiban intracoronary bolus-only|DRUG: tirofiban intravenous bolus plus infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Prospective, Pre-market, Multi-center Study of Insignia Hip Stem in THA to Determine Implant Survivorship and PROMS.
Status: NOT_YET_RECRUITING
Conditions: Arthritis (E.G., Degenerative Joint Disease (DJD), Osteoarthritis, and Rheumatoid Arthritis (RA))
Interventions: DEVICE: Hip stem prosthesis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessing the Efficacy and Tolerability of AZARGA® (Brinzolamide 1%/Timolol 0.5% Fixed Combination) as Replacement Therapy in Patients on COMBIGAN® (Brimonidine 0.2%/Timolol 0.5% Fixed Combination) Therapy in Brazil
Status: TERMINATED
Conditions: Glaucoma
Interventions: DRUG: Brinzolamide/timolol maleate fixed combination
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Ganciclovir Capsules in the Treatment of Refractory Moderate-to-severe Allergic Rhinitis
Status: RECRUITING
Conditions: Rhinitis, Allergic
Interventions: DRUG: Ganciclovir Oral Capsule|DRUG: Ganciclovir Simulant Oral Capsule|DRUG: Mometasone Nasal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Accuracy of Selective Laser Sinteredcomputer Guided Stents Versus Digital Light Processing Stents
Status: COMPLETED
Conditions: Immediate Dental Implants
Interventions: DEVICE: selective laser sintered stent|DEVICE: digital light processing(dlp)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study of Cadonilimab Combined With Bevacizumab and Chemotherapy for Advanced Nonsquamous Non-small Cell Lung Cancer Patients With Untreated Brain Metastases
Status: NOT_YET_RECRUITING
Conditions: Non Small Cell Lung Cancer|Brain Metastases
Interventions: DRUG: Cadonilimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Trial of Pembrolizumab Plus Lenvatinib in Advanced Adrenal Cortical Carcinoma
Status: ENROLLING_BY_INVITATION
Conditions: Adrenocortical Carcinoma
Interventions: DRUG: Pembrolizumab / Lenvatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lymphodepletion Plus Adoptive Cell Therapy With High Dose IL-2 in Adolescent and Young Adult Patients With Soft Tissue Sarcoma
Status: COMPLETED
Conditions: Sarcoma
Interventions: DRUG: TIL|DRUG: Interleukin-2|DRUG: Fludarabine|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety and Efficacy Study Evaluating CTX110 in Subjects With Relapsed or Refractory B-Cell Malignancies (CARBON)
Status: ACTIVE_NOT_RECRUITING
Conditions: B-cell Malignancy|Non-Hodgkin Lymphoma|B-cell Lymphoma|Adult B Cell ALL
Interventions: BIOLOGICAL: CTX110
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare Human Thrombin Against Bovine Thrombin in Its Ability to Stop Bleeding After Surgery
Status: COMPLETED
Conditions: Cardiovascular, Neurologic (Spine), and General Surgery
Interventions: DRUG: Human Thrombin|DRUG: Bovine Thrombin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose:
Clinical trial: Novel Endoscopic Resection of Upper Gastrointestinal Subepithelial Tumors Originating From the Muscularis Propria
Status: COMPLETED
Conditions: Gastric Subepithelial Tumor
Interventions: DEVICE: Forcep
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Liposomal Bupivacaine Use in Alveolar Bone Graft Patients
Status: RECRUITING
Conditions: Cleft Lip and Palate
Interventions: DRUG: Liposomal Bupivacaine|DRUG: Bupivacain|DRUG: Epinephrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Individualized Fortification of Human Milk for Infants Born ≤ 1250 g (MaxiMoM-InForM)
Status: RECRUITING
Conditions: Very Low Birth Weight Infant
Interventions: OTHER: Standard fortification|OTHER: Target fortification|OTHER: BUN adjustable fortification
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Abatacept for SLE Arthritis (IM101-330)
Status: TERMINATED
Conditions: Systemic Lupus Erythematosus Arthritis
Interventions: BIOLOGICAL: abatacept also known as Orencia also known as CTLA4-Ig|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Gene Therapy Using a Lentiviral Vector to Treat X-linked Chronic Granulomatous Disease
Status: RECRUITING
Conditions: Granulomatous Disease, Chronic, X-linked
Interventions: BIOLOGICAL: Lentiviral G1XCGD Gene Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Methylphenidate and Exercise in Reducing Cancer-Related Fatigue in Patients With Prostate Cancer
Status: RECRUITING
Conditions: Prostate Carcinoma
Interventions: BEHAVIORAL: Exercise Intervention|DRUG: Methylphenidate|OTHER: Placebo|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration|OTHER: Stretching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Chairside Time and Accuracy of Indirect Bonding of Orthodontic Attachments Using Double Versus Single Transfer Tray
Status: UNKNOWN
Conditions: Orthodontic Appliance Complication
Interventions: DEVICE: double transfer trays|DEVICE: single transfer tray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Intravitreal Bevacizumab for Surgical Treatment of Severe Proliferative Diabetic Retinopathy
Status: COMPLETED
Conditions: Proliferative Diabetic Retinopathy
Interventions: DRUG: Bevacizumab|OTHER: sham
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: The Effects of Inhaled Aclidinium Bromide/Formoterol Fumarate on Inspiratory Pleural Pressures in Smokers
Status: COMPLETED
Conditions: Smoking
Interventions: DRUG: Aclidinium bromide/formoterol fumarate dihydrate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Nitazoxanide, Peginterferon, and Ribavirin Combination Therapies in the Treatment of Chronic Hepatitis C
Status: COMPLETED
Conditions: Chronic Hepatitis C
Interventions: DRUG: Nitazoxanide|BIOLOGICAL: Peginterferon alfa-2a|BIOLOGICAL: Peginterferon alfa-2a|DRUG: Ribavirin|DRUG: Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Platelet-rich Plasma in the Sacroiliac Joint
Status: COMPLETED
Conditions: Sacroiliac Joint Arthritis
Interventions: PROCEDURE: PRP|PROCEDURE: Steroid Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Iron-fortified Lentils to Improve Iron (Fe) Status in Bangladesh
Status: UNKNOWN
Conditions: Anemia, Iron-Deficiency|Cognitive Performance|Iron-deficiency
Interventions: DIETARY_SUPPLEMENT: Iron fortified lentils|OTHER: Non Iron-fortified lentils|OTHER: Usual Intake
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Reducing COVID-19 Vaccine Hesitancy Among Hispanic Parents
Status: RECRUITING
Conditions: Vaccine-Preventable Diseases|COVID-19 Pandemic|Health-Related Behavior|Health Knowledge, Attitudes, Practice|Narration
Interventions: BEHAVIORAL: Baseline surveys|BEHAVIORAL: Digital Storytelling Intervention|BEHAVIORAL: Information Control Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Eight-week Concurrent Training on Functional Capacity in Patients With Unilateral Transtibial Amputation
Status: COMPLETED
Conditions: Amputation of Lower Limb Above Knee|Sequelae
Interventions: OTHER: Concurrent Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Postoperative Safety Outcomes of Intraoperative Intracameral Preservative-Free Moxifloxacin Versus Levofloxacin
Status: COMPLETED
Conditions: Cataract Senile|Endophthalmitis|Antibiotic Side Effect|Safety Issues
Interventions: DRUG: Levofloxacin Ophthalmic|DRUG: Moxifloxacin Ophthalmic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Phase II Study to Evaluate the Efficacy of TKI258 for the Treatment of Patients With FGFR2 Mutated or Wild-type Advanced and/or Metastatic Endometrial Cancer
Status: COMPLETED
Conditions: Solid Tumors and Advanced Endometrial Cancer|Endometrial Cancer|Second-line Treatment|VEGF
Interventions: DRUG: TKI258
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Complete Digital Workflow for Construction of Full Arch Implant Supported Screw Retained Restoration
Status: ACTIVE_NOT_RECRUITING
Conditions: Accuracy
Interventions: OTHER: full arch implant supported screw retained restoration with conventional impression technique|OTHER: full arch implant supported screw retained restoration with conventional digital technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of State and Shade of White Spot Lesions After Using Different Remineralizing Agents (An in Vivo Study)
Status: COMPLETED
Conditions: White Spot Lesion
Interventions: OTHER: Biomimetic remineralizing agent|OTHER: Resin Modified Glass Ionomer Varnish
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigation of the Efficacy of Quinine Sulphate Administered Via Taste-Masked Pellets to Children With Falciparum Malaria
Status: COMPLETED
Conditions: Malaria
Interventions: DRUG: Administration of quinine sulphate taste-masked pellets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigation of Thermal Injury on Intestinal Permeability in Both Thermal Injury and Healthy Participants
Status: TERMINATED
Conditions: Burns
Interventions: OTHER: Lactulose and Mannitol solution|OTHER: Sucralose
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A 3-YEAR CLINICAL INVESTIGATION ON THE NOBEL ACTIVE® TIULTRA™ IMPLANT AND ON1™ BASE XEAL1™ _____________________________________________________________
Status: UNKNOWN
Conditions: to Study Soft Tissue Health and Stability
Interventions: DEVICE: NobelActive® TiUltra™ implants and On1™ Base/Xeal™ along with On1 components
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Minimizing Fall-Related Injury in Older Adults: a Motor Learning Approach
Status: COMPLETED
Conditions: Fall Injury|Fall Patients|Mobility Limitation
Interventions: OTHER: FAST Program|OTHER: Otago Exercise Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pitavastatin Pre-Treatment Study in Patient With Elective PCI for Stable Angina Pectoris (PIPA)
Status: WITHDRAWN
Conditions: Percutaneous Coronary Intervention
Interventions: DRUG: Pitavastatin|DRUG: Pitavastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy Study of Conbercept in Diabetic Macular Edema (DME) (Sailing)
Status: UNKNOWN
Conditions: Diabetic Macular Edema
Interventions: DRUG: Conbercept|OTHER: Sham injection|PROCEDURE: Laser|OTHER: Sham laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Paraurethral Transplantation of Autologous Muscle Derived Stem Cells for Treatment of Stress Incontinency
Status: COMPLETED
Conditions: Stress Urine Incontinency
Interventions: BIOLOGICAL: paraurethral injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Descriptive Study of Brain Velocity in Transcranial Doppler in Newborns Over 35 Weeks of Gestational Age in the Maternity Ward
Status: COMPLETED
Conditions: Newborn
Interventions: DIAGNOSTIC_TEST: transcranial doppler ultrasound scan|DIAGNOSTIC_TEST: ultrasound scan centered on the arterial canal
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Integrating Psychotropic Medication Into the Care of People With Mental Disorders in a Prayer Camp in Ghana
Status: COMPLETED
Conditions: Schizophrenia|Mood Disorders,|Anxiety Disorder
Interventions: DRUG: olanzapine|DRUG: risperidone|DRUG: amitryptaline|DRUG: fluoxetine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Artificial Intelligence and Dysplasia Detection in Ulcerative Colitis (CUDISIA Study)
Status: COMPLETED
Conditions: Ulcerative Colitis|Dysplasia
Interventions: DEVICE: DiscoveryTM|DEVICE: iSCAN
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Cinacalcet in Management of Secondary Hyperparathyroidism in Haemodialysis Patients
Status: UNKNOWN
Conditions: Secondary Hyperparathyroidism
Interventions: DRUG: Combination Cinacalcet with Vitamin D analogue
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Studies of the Ocular Complications of AIDS (SOCA)--Cytomegalovirus Retinitis Retreatment Trial (CRRT)
Status: COMPLETED
Conditions: HIV Infections|Acquired Immunodeficiency Syndrome|Cytomegalovirus Retinitis
Interventions: DRUG: Ganciclovir|DRUG: Foscarnet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Intrahepatic Arterial Infusion of TG6002 in Combination With 5-FC in Patients With Metastatic Colorectal Cancer
Status: TERMINATED
Conditions: Colorectal Neoplasms
Interventions: BIOLOGICAL: TG6002|DRUG: Flucytosine (5-FC)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Standard vs. Biofilm Susceptibility Testing in Cystic Fibrosis (CF)
Status: COMPLETED
Conditions: Cystic Fibrosis|Chronic Bronchitis
Interventions: DRUG: IV amikacin|DRUG: PO azithromycin|DRUG: IV ceftazidime|DRUG: PO ciprofloxacin|DRUG: IV meropenem|DRUG: IV piperacillin-tazobactam|DRUG: IV ticarcillin-clavulanate|DRUG: IV tobramycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Safety and Pharmacokinetics of Carbavance™ (RPX2014/RPX7009) in Subjects With Renal Insufficiency
Status: COMPLETED
Conditions: Subjects With Varying Degrees of Renal Insufficiency and|Subjects With Normal Renal Function
Interventions: DRUG: RPX7009 and RPX2014
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of AFL-assisted PDT in Microinvasive Squamous Cell Carcinoma
Status: COMPLETED
Conditions: Microinvasive Squamous Cell Carcinoma
Interventions: DRUG: lidocaine-prilocaine 5% cream application|DEVICE: 2940-nm Er:YAG AFL pretreatment|DRUG: methyl-aminolevulinate application|DEVICE: Illuminating using red light-emitting diode lamps
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cerebral and Circulatory Effects of Neonatal Volume Targeted Ventilation
Status: COMPLETED
Conditions: Respiratory Distress Syndrome, Newborn|Respiratory Failure|Premature Birth
Interventions: OTHER: volume guarantee|OTHER: pressure-controlled
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Learning and Food Form on Intake in Humans
Status: COMPLETED
Conditions: Obesity
Interventions: BEHAVIORAL: Metabolic effects of consuming energy dense beverages|BEHAVIORAL: energy dense solid food|BEHAVIORAL: Energy dilute beverages|BEHAVIORAL: Energy dilute solid food
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Low-Dose Oral Minoxidil as Treatment of Permanent Chemotherapy-Induced Alopecia
Status: ACTIVE_NOT_RECRUITING
Conditions: Permanent Chemotherapy-induced Alopecia
Interventions: DRUG: oral minoxidil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improved Oral Bioavailability of Curcumin Incorporated Into Micelles
Status: COMPLETED
Conditions: Pharmacokinetics of New Curcumin Formulations|Safety of New Curcumin Formulations
Interventions: DIETARY_SUPPLEMENT: curcumin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: LEAn Body Mass Normalization of OXaliplatin Based Chemotherapy
Status: ACTIVE_NOT_RECRUITING
Conditions: Stage III Colon Cancer
Interventions: DRUG: Oxaliplatin|DRUG: Oxaliplatin LBM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of V.A.C. VERAFLO CLEANSE CHOICE™ Dressing Using Normal Saline to Promote Increased Healthy Wound Bed Tissue
Status: TERMINATED
Conditions: Wound|Wound Heal|Wounds and Injuries|Granulation Tissue|Negative-pressure Wound Therapy
Interventions: DEVICE: V.A.C. VERAFLO CLEANSE CHOICE™ dressing with Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reirradiation With Concomitant Chemotherapy After Salvage Surgery for Recurrence of Head and Neck Cancer in Irradiated Area
Status: UNKNOWN
Conditions: Recurrence of Head and Cancer in Irraiated Area
Interventions: PROCEDURE: Reirradiation with concomitant chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Yield of Implantable Cardiac Monitoring Device in Patients With Acute Ischemic Stroke.
Status: RECRUITING
Conditions: Stroke, Acute|Stroke|Stroke, Ischemic|Atrial Fibrillation
Interventions: DEVICE: Reveal LINQTM
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: CT C-spine Audit and Feedback
Status: COMPLETED
Conditions: Cervical Spine Injury|Emergencies|Trauma
Interventions: BEHAVIORAL: Audit and Feedback on Individual Practice Patterns
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Determination Physical Activity Levels,Quality Life,Depression and Fatigue Severity Individuals With Metabolic Syndrome
Status: COMPLETED
Conditions: Metabolic Syndrome
Interventions: OTHER: PHYSICAL ACTIVITY LEVELS|OTHER: DEPRESSION LEVELS|OTHER: FATİGUE SEVERİTY|OTHER: QUALITY OF LIFE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Study of HUCNS-SC Subretinal Transplantation in Subjects With GA of AMD
Status: TERMINATED
Conditions: Age-Related Macular Degeneration
Interventions: BIOLOGICAL: HuCNS-SC sub-retinal transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Expanding Live Donor Kidney Transplantation Through Advocacy Training and Social Media
Status: ACTIVE_NOT_RECRUITING
Conditions: Kidney Failure|Kidney Diseases
Interventions: BEHAVIORAL: Facebook App|BEHAVIORAL: Live Donor Champion + Facebook App
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Evaluation of a Mindfulness Intervention to Prevent Chemo-brain in Women Preparing for Chemotherapy for Breast Cancer
Status: RECRUITING
Conditions: Breast Carcinoma
Interventions: BEHAVIORAL: Mindfulness Relaxation|PROCEDURE: Functional Magnetic Resonance Imaging|PROCEDURE: Biospecimen Collection|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Neomycin and Rifaximin Plus Neomycin in Treating Methane Positive Constipation Predominant Irritable Bowel Syndrome
Status: COMPLETED
Conditions: Constipation-predominant Irritable Bowel Syndrome
Interventions: DRUG: Neomycin|DRUG: Placebo|DRUG: Rifaximin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pentostatin, Cyclophosphamide, and Rituximab in Treating Patients With Previously Untreated Chronic Lymphocytic Leukemia
Status: COMPLETED
Conditions: Leukemia|Lymphoma
Interventions: BIOLOGICAL: rituximab|DRUG: cyclophosphamide|DRUG: pentostatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pevonedistat, Irinotecan, and Temozolomide in Treating Patients With Recurrent or Refractory Solid Tumors or Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Recurrent Lymphoma|Recurrent Malignant Solid Neoplasm|Recurrent Primary Central Nervous System Neoplasm|Refractory Lymphoma|Refractory Malignant Solid Neoplasm|Refractory Primary Central Nervous System Neoplasm
Interventions: DRUG: Irinotecan|DRUG: Pevonedistat|DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Surgical Treatment of Periimplantitis in Patients With Risk Factors
Status: UNKNOWN
Conditions: Peri-Implantitis|Type 2 Diabetes Mellitus|Smoking, Cigarette|Periodontal Diseases
Interventions: PROCEDURE: Non-Surgical treatment|PROCEDURE: Surgical Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing Minisling to Tension Free Vaginal Tape in Mangement of Stress Urinary Incontinence
Status: COMPLETED
Conditions: Stress Urinary Incontinence
Interventions: PROCEDURE: single incision minisling|PROCEDURE: tension free vaginal tape
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The UK Plasma Based Molecular Profiling of Advanced Breast Cancer to Inform Therapeutic CHoices (plasmaMATCH) Trial
Status: UNKNOWN
Conditions: Advanced Breast Cancer
Interventions: DRUG: Fulvestrant|DRUG: Neratinib|DRUG: AZD5363|DRUG: Olaparib|DRUG: AZD6738
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: E7 TCR T Cell Immunotherapy for High-Grade Cervical Intraepithelial Neoplasia
Status: WITHDRAWN
Conditions: Cervical Intraepithelial Neoplasia
Interventions: BIOLOGICAL: E7 TCR
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy of Sativex in Relieving Symptoms of Spasticity Due to Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DRUG: Sativex|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Management of Volume Overload HF Patients by Individual DSR Treatment adJustment-a clinicAl inVestigation of InfusatE2.0
Status: RECRUITING
Conditions: Heart Failure|Volume Overload
Interventions: DRUG: Direct Sodium Removal Infusate 2.0
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase Ib Study of Gemcitabine Plus Cisplatin or Carboplatin Plus Dovitinib in Patients With Advanced Solid Tumors
Status: TERMINATED
Conditions: Solid Tumors|Bladder Cancer
Interventions: DRUG: Cisplatin|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of Specific Immunotherapy With Pollinex Quattro (Tree-/Grass Pollen) on Allergen-specific Immunoglobulin E (IgE) Levels
Status: COMPLETED
Conditions: Rhinitis, Allergic|Respiratory Tract Infections|Allergy|Allergic Asthma|Allergic Conjunctivitis
Interventions: DRUG: Pollinex Quattro with tree- and grass pollen extracts and their mixtures
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: a Clinical Research of CD19 and CD22 Targeted Prime CAR-T Cell in Relapsed/Refractory B-ALL
Status: RECRUITING
Conditions: B-ALL
Interventions: BIOLOGICAL: CD19 and CD22 targeted prime CAR-T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Striatal Dopamine Transporter Density in Post-Traumatic Stress Disorder (PTSD)
Status: UNKNOWN
Conditions: Post-traumatic Stress Disorder
Interventions: DIAGNOSTIC_TEST: MRI using DaTscan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Single Centre, Prospective Feasibility Study to Evaluate the Efficacy of an Endoluminal-suturing Device (Endomina) on Severe Obstructive Sleep Apnea Syndrome
Status: COMPLETED
Conditions: Sleep Apnea Syndromes|Overweight and Obesity
Interventions: DEVICE: Endomina- Endoscopic Sleeve Gastroplasty|BEHAVIORAL: Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Life Story Book for Older Adults and live-in Migrant Caregivers
Status: UNKNOWN
Conditions: Home Caregiver-older Adults Relationship
Interventions: BEHAVIORAL: Life Story Book|BEHAVIORAL: Self-selected social activities
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: 68Ga-FAPI PET/CT in Patients With Various Fibrotic Disease
Status: RECRUITING
Conditions: Fibrosis|Positron-Emission Tomography
Interventions: DRUG: 68Ga-FAPI-04
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Research of Intensive Lifestyle Intervention for PCOS Patients With IGT
Status: COMPLETED
Conditions: Polycystic Ovary Syndrome
Interventions: BEHAVIORAL: intensive lifestyle intervention|DRUG: GLP-1 Receptor Agonists|DRUG: Metformin|DRUG: Acarbose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EMG-guided Botox Injection Versus Conventional Botox Injection in Gummy Smile Patients
Status: NOT_YET_RECRUITING
Conditions: Excessive Gingival Display
Interventions: PROCEDURE: Botox injection|DEVICE: EMG|DRUG: Zinc Supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT