pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Evaluation of the Effectiveness of Hormonal Treatment in Adolescents Suffering From Gender Dysphoria
Status: NOT_YET_RECRUITING
Conditions: Cross Sex Hormonal Treatment in Adolescents With Gender Dysphoria
Interventions: DRUG: hormonal treatment with cross sex hormones (testosterone or oestrogenes) started at 14 years old +/- 6 months|DRUG: Cross sex hormones ( œstrogenes or testosterone) started at 16 years old +/- 6 months
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Icotinib or Whole Brain Irradiation in EGFR-mutant Lung Cancer
Status: COMPLETED
Conditions: Brain Metastasis|Non Small Cell Lung Cancer
Interventions: RADIATION: whole brain radiation(WBI)|DRUG: Icotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Individualized Selection of PEEP in Patients Affected by Expiratory Flow Limitation
Status: NOT_YET_RECRUITING
Conditions: Postoperative Complications|Mechanical Ventilation Complication
Interventions: PROCEDURE: Mechanical ventilation setting (Positive end-expiratory pressure) according to Expiratory Flow Limitation|PROCEDURE: Mechanical ventilation setting (Positive end-expiratory pressure) not according to Expiratory Flow Limitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 14-C ADME (Absorption, Disposition, Metabolism and Excretion) Study in Man
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: SLV337 suspension|DRUG: SLV337 capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Flibanserin for the Treatment of Hypoactive Sexual Desire Disorder in Postmenopausal Women in North America
Status: TERMINATED
Conditions: Sexual Dysfunctions, Psychological
Interventions: DRUG: Flibanserin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Equivalence of New Breath AnalyzerCompared to Currently BreathID System in Assessment of Liver Function
Status: COMPLETED
Conditions: Chronic Liver Disease (CLD)|Healthy Volunteers
Interventions: DEVICE: MPBA System|DEVICE: BreathID
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety and Efficacy Analysis of an Antibody Associated With a Chemotherapy for Patients With a Triple Negative Metastatic Breast Cancer
Status: RECRUITING
Conditions: Triple Negative Breast Cancer|Metastatic Breast Cancer
Interventions: DRUG: Sacituzumab govitecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mesoblast Stem Cell Therapy for Patients With Single Ventricle and Borderline Left Ventricle
Status: ACTIVE_NOT_RECRUITING
Conditions: Hypoplastic Left Heart Syndrome|Atrioventricular Canal
Interventions: BIOLOGICAL: MPC; rexlemestrocel-L
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pathways, a Hope Intervention to Support Personal Goal Pursuit, Mental Health, and Quality of Life During Advanced Lung Cancer Treatment
Status: RECRUITING
Conditions: Lung Cancer
Interventions: BEHAVIORAL: Pathways|BEHAVIORAL: Enhanced Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficiency of a Composite Personalised Care on Functional Outcome in Early Psychosis
Status: NOT_YET_RECRUITING
Conditions: Psychosis
Interventions: BEHAVIORAL: Cognitive training|DRUG: Personalized neuroprotective strategies : Vitamin B12, folinic acid, Omega 3, NAC|OTHER: Treatment as usual (TAU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Intra-tumoral Administered MTX110 in Patients With Recurrent Glioblastoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Recurrent Glioblastoma
Interventions: DRUG: MTX110|DEVICE: Programmable pump and catheter system
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Decitabine in Treating Patients With Previously Untreated Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities|Adult Acute Myeloid Leukemia With Del(5q)|Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)|Adult Acute Myeloid Leukemia With t(15;17)(q22;q12)|Adult Acute Myeloid Leukemia With t(16;16)(p13;q22)|Adult Acute Myeloid Leukemia With t(8;21)(q22;q22)|Secondary Acute Myeloid Leukemia|Untreated Adult Acute Myeloid Leukemia
Interventions: DRUG: decitabine|OTHER: laboratory biomarker analysis|OTHER: pharmacological study|OTHER: high performance liquid chromatography|GENETIC: microarray analysis|GENETIC: RNA analysis|OTHER: mass spectrometry|GENETIC: DNA methylation analysis|OTHER: matrix-assisted laser desorption/ionization time of flight mass spectrometry
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Elderly Back Pain: Comparing Chiropractic to Medical Care
Status: COMPLETED
Conditions: Subacute Low Back Pain|Chronic Low Back Pain
Interventions: OTHER: HVLA-SM|OTHER: LVVA-SM|DRUG: Usual medical care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Norfloxacin Versus Ciprofloxacin for Spontaneous Bacterial Peritonitis (SBP) Prevention
Status: COMPLETED
Conditions: Adverse Reaction to Other Drugs and Medicines
Interventions: DRUG: Norfloxacin|DRUG: ciprofloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of a GLP-1 Analogue in Patients With Type 2 Diabetes Treated With Metformin.
Status: COMPLETED
Conditions: Diabetes Mellitus Type 2
Interventions: DRUG: Placebo|DRUG: taspoglutide|DRUG: taspoglutide|DRUG: taspoglutide|DRUG: taspoglutide|DRUG: taspoglutide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Influence of Post-thaw Embryo Culture Interval on Assisted Reproduction Success Rates
Status: COMPLETED
Conditions: Infertility
Interventions: PROCEDURE: embryo transfer after thaw and culture|PROCEDURE: embryo transfer with no culture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rituximab Combined With Chidamide and Lenalidomide for r/r AITL
Status: UNKNOWN
Conditions: Angioimmunoblastic T-cell Lymphoma|Chemotherapy Effect|Chemotherapeutic Toxicity
Interventions: DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Ripretinib vs Sunitinib in Advanced GIST Patients After Treatment With Imatinib
Status: ACTIVE_NOT_RECRUITING
Conditions: Gastrointestinal Stromal Tumors
Interventions: DRUG: Ripretinib|DRUG: Sunitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Central Retinal Vein Occlusion (CRVO) Treatment With Bevacizumab and Dexamethasone or Bevacizumab Only.
Status: UNKNOWN
Conditions: Central Retinal Vein Occlusion
Interventions: DRUG: Bevacizumab Ophthalmic and Intravitreal Dexamethasone.|DRUG: Bevacizumab Ophthalmic.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rituximab in Patients With ST-elevation Myocardial Infarction
Status: RECRUITING
Conditions: ST Elevated Myocardial Infarction
Interventions: DRUG: Active arm 200 mg|DRUG: Active arm 1000 mg|DRUG: Placebo arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Stellate Ganglion Block on Hot Flashes in Hispanic Women With Breast Cancer
Status: TERMINATED
Conditions: Hot Flashes|Hot Flushes|Vasomotor Symptoms
Interventions: DRUG: Stellate Ganglion Block injection with bupivicaine|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Postprandial Glycemia in Orange Products
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Orange Juice1|DIETARY_SUPPLEMENT: Orange Juice2|DIETARY_SUPPLEMENT: Raw Orange
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect of Topical Tranexamic Acid on Postoperative Bleeding From Superficial Wounds
Status: COMPLETED
Conditions: Postoperative Hemorrhage|Injuries and Wounds
Interventions: DRUG: Tranexamic Acid|DRUG: saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Pilot Trial of Herpesvirus Treatment in Idiopathic Pulmonary Fibrosis (IPF)
Status: COMPLETED
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: DRUG: Valganciclovir|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: DEXTENZA in Pediatric Patients Following Retinal Surgery or Laser Treatment Under Anesthesia
Status: RECRUITING
Conditions: Vitreoretinopathy|Coats' Disease|Exudative Retinopathy|Lattice Degeneration|Retinal Hole|Sickler's Syndrome|Retinal Detachment Rhegmatogenous|Retinal Detachment Exudative|Retinal Detachment Traction
Interventions: DRUG: Dextenza 0.4Mg Ophthalmic Insert|DRUG: Pred Forte
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Targeting of Preventive Treatment for Adolescents at Risk of Oral Diseases
Status: RECRUITING
Conditions: Dental Caries in Children|Dental Plaque|Tooth Decay|Periodontitis
Interventions: DEVICE: Lumoral Treatment|OTHER: Standard, personalized oral health care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Cognitive Remediation Intervention to Prepare for Transition of Care
Status: RECRUITING
Conditions: Sickle Cell Disease|Cognitive Impairment|Adolescent Behavior|Self Efficacy|Health-Related Behavior|Coping Skills
Interventions: BEHAVIORAL: CREADY (Cognitive-Remediation of Executive and Adaptive Deficits in Youth)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of Efficacy of the EPIC™ Self-Expanding Nitinol Vascular Stent
Status: COMPLETED
Conditions: Peripheral Arterial Diseases|Superficial Femoral Artery Stenosis
Interventions: DEVICE: EPIC™ Self-Expanding Nitinol Vascular Stent
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vancomycin Treatment in Recurrent PSC in Liver Transplant Patients
Status: WITHDRAWN
Conditions: Primary Sclerosing Cholangitis|Post- Orthotopic Liver Transplantation
Interventions: DRUG: Vancomycin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A 52-week, Placebo-controlled Study to Evaluate the Efficacy and Safety of 2 Doses of CHF6001 DPI (Tanimilast), as add-on to Maintenance Triple Therapy in Subjects With COPD and Chronic Bronchitis (PILASTER)
Status: RECRUITING
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Experimental: CHF6001 1600µg|DRUG: Experimental: CHF6001 3200µg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Study of NGM282 in Patients With Primary Biliary Cirrhosis
Status: COMPLETED
Conditions: Primary Biliary Cirrhosis
Interventions: BIOLOGICAL: NGM282|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Numerical Standard of Anthropomorphicity of Prosthetic Feet for Improvement of Amputee Performance
Status: NOT_YET_RECRUITING
Conditions: Testing of Methodology of Attachment of External Foot Prothesis Based on Anthropomorphism Criteria
Interventions: OTHER: Methodology of attachment of external foot prothesis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Prospective Randomized Trial of Monocryl Versus Nylon Suture Closure in Carpal Tunnel Surgery
Status: COMPLETED
Conditions: Carpal Tunnel Syndrome
Interventions: PROCEDURE: Monocryl|PROCEDURE: Nylon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Changes of Oropharyngeal Flora
Status: COMPLETED
Conditions: Pharyngeal Bacterial Colonization|Pneumonia
Interventions: DIETARY_SUPPLEMENT: Probiotics|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Using Health-related Quality of Life (HRQL) in Routine Clinical Care
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease|Pulmonary Fibrosis|Pulmonary Hypertension|Cystic Fibrosis
Interventions: BEHAVIORAL: HUI score card
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Bifocal Right Ventricular PAcing in Right Bundle Branch blocK and Heart Failure With Reduced Ejection Fraction. The Study Tests the Superiority of Right Ventricular Bifocal Stimulation Over VVI Implantable Defibrillator in Right Bundle Branch Block and Heart Failure.
Status: TERMINATED
Conditions: Right Bundle-Branch Block|Heart Failure With Reduced Ejection Fraction|Bifocal Stimulation
Interventions: DEVICE: Compare VVi mode versus DDD bifocal stimulation through crossover randomization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of a Mouthwash Containing Propolis
Status: UNKNOWN
Conditions: Gingivitis|Periodontitis|Plaque|Inflammation
Interventions: DRUG: Propolis|DRUG: chlorhexidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: ESAs, Reticulocyte Dynamic and Hemoglobin Variability
Status: COMPLETED
Conditions: Erythropoiesis Stimulating Agent Pharmacodynamics
Interventions: DRUG: comparison between darbepoetin alfa and C.E.R.A. and different administration intervals
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antiretroviral Regime for Viral Eradication in Newborns
Status: COMPLETED
Conditions: HIV/AIDS and Infections
Interventions: DRUG: Zidovudine|DRUG: Nevirapine|DRUG: Lamivudine|DRUG: Lopinavir/ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Sleeper's and Adduction Stretch to Increase Shoulder ROM
Status: COMPLETED
Conditions: Stiffness of Shoulder, Not Elsewhere Classified
Interventions: OTHER: Modified sleeper stretching|OTHER: Modified cross-body adduction stretch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nitric Oxide to Treat Pulmonary Embolism
Status: COMPLETED
Conditions: Pulmonary Embolism
Interventions: DRUG: Inhaled Nitric Oxide|DRUG: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility Study to Evaluate RECELL and Melanocyte Keratinocyte Transplantation Procedure for Repigmentation of Stable Vitiligo Lesions
Status: TERMINATED
Conditions: Vitiligo
Interventions: PROCEDURE: Melanocyte-Keratinocyte Transplantation and Ultraviolet Lamp (UVB)|DEVICE: RECELL 1:5 and Ultraviolet Lamp (UVB)|DEVICE: RECELL 1:10 and Ultraviolet Lamp (UVB)|DEVICE: RECELL 1:20 and Ultraviolet Lamp (UVB)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Safety of Liraglutide in Pediatric Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: liraglutide|DRUG: placebo|DRUG: liraglutide|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of NeoRecormon (Epoetin Beta) in Patients With End Stage Renal Disease.
Status: COMPLETED
Conditions: Anemia
Interventions: DRUG: epoetin beta [NeoRecormon]
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Targeted Laser in Diabetic Macular Edema
Status: UNKNOWN
Conditions: Macular Edema|Diabetic Retinopathy
Interventions: PROCEDURE: Indocyanine green-Guided Targeted Laser photocoagulation|PROCEDURE: Sham laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Interventions for Clinical High Risk Youth in Tunisia
Status: RECRUITING
Conditions: Stress, Psychological|Depression, Anxiety|Prodromal Period
Interventions: BEHAVIORAL: Psychosocial Intervention|BEHAVIORAL: Enhanced - Treatment as Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Outcomes in Patients With Fractured Neck of Femur During the COVID-19 Pandemic
Status: COMPLETED
Conditions: Femoral Neck Fractures|SARS-CoV 2
Interventions: OTHER: Surgery: Dynamic Hip Screw, hemiarthroplasty, hip replacement, intramedullary nail
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Eflornithine in Treating Patients At High Risk of Developing Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: eflornithine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Dietary Nitrate Supplements and Ischemic Stroke Recovery
Status: COMPLETED
Conditions: Stroke|Ischemic Stroke|Cerebrovascular Accident
Interventions: DRUG: Beet it Beetroot juice|DRUG: Beet It Placebo Beetroot juice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Neurobiology of Serotonin and Addiction
Status: COMPLETED
Conditions: Cocaine Dependence
Interventions: DRUG: Escitalopram|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Auditory-motor Coupling in Multiple Sclerosis With Cerebellar Lesions
Status: RECRUITING
Conditions: Multiple Sclerosis|Cerebral Lesion
Interventions: OTHER: motor entrainment to auditory cues and music during walking on quality of movement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Medication-related Osteonecrosis of the Jaw (MRONJ) Registry
Status: ACTIVE_NOT_RECRUITING
Conditions: Medication-related Osteonecrosis of the Jaw|Bisphosphonate-Associated Osteonecrosis of the Jaw
Interventions: PROCEDURE: Conservative treatment|PROCEDURE: Surgical treatment|PROCEDURE: Adjuvant non-surgical treatment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: S9916, Combination Therapy in Treating Patients With Advanced Prostate Cancer That Has Not Responded to Hormone Therapy
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: docetaxel|DRUG: estramustine|DRUG: mitoxantrone|DRUG: prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intranasal Glulisine in Amnestic Mild Cognitive Impairment and Probable Mild Alzheimer's Disease
Status: TERMINATED
Conditions: Mild Cognitive Impairment|Alzheimer's Disease (AD)
Interventions: DRUG: Insulin glulisine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Ultrasound Guided Genicular Nerve Block and Periarticular Infiltration in Knee Arthroplasty
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: PROCEDURE: periarticular infiltration|PROCEDURE: genicular nerve block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Thalidomide and Epoetin Alfa in Treating Anemia in Patients With Myelodysplastic Syndrome
Status: COMPLETED
Conditions: Anemia|Leukemia|Myelodysplastic Syndromes|Myelodysplastic/Myeloproliferative Neoplasms
Interventions: BIOLOGICAL: epoetin alfa|DRUG: thalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Cognitive Behavioral Therapy for the Prevention of Paranoia in Adolescents at High Risk
Status: COMPLETED
Conditions: ARMS|APS|Prodromal Symptoms
Interventions: BEHAVIORAL: Cognitive Behavioral Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effectiveness of Biomimetic Materials in Preventing Enamel Demineralization During Fixed Orthodontic Treatment
Status: ACTIVE_NOT_RECRUITING
Conditions: Enamel Hypomineralization, Dental
Interventions: COMBINATION_PRODUCT: Curasept Biosmalto Mousse and toothpaste|OTHER: Colgate toothpaste
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of 123-I Iodobenzovesamicol (IBVM) and SPECT Imaging of Healthy Subjects and Patients With Alzheimer Disease
Status: COMPLETED
Conditions: Alzheimer Disease|Parkinson Disease
Interventions: DRUG: [123I]-IBVM
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Study Of Single-dose Cyclophosphamide +Pembrolizumab In Patients With Metastatic Triple Negative Breast Cancer
Status: COMPLETED
Conditions: Triple Negative Breast Cancer
Interventions: DRUG: Pembrolizumab|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endoscopic Ultrasound Plus Submucosal Injection for Early Esophageal Cancer
Status: UNKNOWN
Conditions: Esophageal Cancer
Interventions: DEVICE: submucosal injection needle ; EUS|DEVICE: ordinary endosonography(EUS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Nutrition Support to Improve Outcomes in Patients With Unresectable Pancreatic Cancer
Status: TERMINATED
Conditions: Cancer of Pancreas
Interventions: DIETARY_SUPPLEMENT: Nutrawell Powder|OTHER: Diet Only|DIETARY_SUPPLEMENT: OmegaRich fish oil supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rose Bengal Electromagnetic Activation With Green Light for Infection Reduction
Status: ACTIVE_NOT_RECRUITING
Conditions: Acanthamoeba Keratitis|Fungal Keratitis
Interventions: DRUG: Moxifloxacin Ophthalmic|DRUG: Chlorhexidine Gluconate|DRUG: Natamycin|DRUG: Rose Bengal|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of PNF on Selective Motor Control and Balance in CP
Status: COMPLETED
Conditions: CP (Cerebral Palsy)
Interventions: OTHER: Proprioceptive neuromuscular facilitation techniques.|OTHER: Traditional physical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Hyperbaric Oxygen for Wagner II Diabetic Lower Extremity Ulcers
Status: TERMINATED
Conditions: Wagner Grade 2 Lower Extremity Ulcers
Interventions: DEVICE: Hyperbaric oxygen therapy|DEVICE: Hyperbaric room air
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Immunogenicity of a Candidate Ebola Vaccine in Adults
Status: COMPLETED
Conditions: Virus Diseases
Interventions: BIOLOGICAL: GlaxoSmithKline (GSK) Biologicals' investigational recombinant chimpanzee adenovirus Type 3-vectored Ebola Zaire vaccine (ChAd3-EBO-Z) (GSK3390107A)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Diagnostic Role of the "White Test" With Lipidic Solution in the Early Intraoperative Identification of Open Bile Ducts for the Prevention of Bile Leakage After Liver Resection (BiLe -Trial)
Status: RECRUITING
Conditions: Bile Leakage
Interventions: DRUG: "white" test" (= the administration of SMOFlipid retrograde through the cystic duct)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study to Evaluate the Efficacy, Safety, Tolerability and Pharmacokinetics of AZD1386 in Patients With Osteoarthritis (OA) of the Knee
Status: TERMINATED
Conditions: Pain
Interventions: DRUG: AZD1386|DRUG: AZD1386|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Memantine in Treating Cocaine-Dependent Individuals - 2
Status: COMPLETED
Conditions: Cocaine-Related Disorders
Interventions: DRUG: Memantine|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Efficacy and Safety of Erenumab in Adult Chronic Migraine Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Migraine
Interventions: BIOLOGICAL: Erenumab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Using Magnetic Field Tracking to Confirm Nasogastric Tube Placement at Point of Care
Status: COMPLETED
Conditions: Enteral and Supplement Feeds Adverse Reaction|Gastrointestinal Diseases|Esophagus Disorder
Interventions: DEVICE: Insertion and withdrawal of a magnetic-tipped wire into the lumen of the nasogastric tube for tracking of its position
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Does Glyceryl Nitrate Prevent Post-Endoscopic Retrograde Cholangiopancreaticography (ERCP) Pancreatitis?
Status: COMPLETED
Conditions: Pancreatitis
Interventions: DRUG: glyceryl nitrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Effect of Nasal Spray Dexmedetomidine on Emergence Delirium Prevention in Total Hip Replacement
Status: NOT_YET_RECRUITING
Conditions: Delirium
Interventions: DRUG: Nasal spray dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Probiotic Combination on Helicobacter Pylori Infection in Children
Status: WITHDRAWN
Conditions: Helicobacter Infections
Interventions: DIETARY_SUPPLEMENT: Gastrus|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dexrazoxane and Cisplatin in Treating Patients With Advanced Solid Tumors
Status: COMPLETED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: cisplatin|DRUG: dexrazoxane hydrochloride|OTHER: high performance liquid chromatography|OTHER: laboratory biomarker analysis|OTHER: mass spectrometry|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Non-invasive Brain Stimulation in Patients With Methamphetamine Use Disorder
Status: UNKNOWN
Conditions: Craving|Depression, Anxiety|Amphetamine Addiction
Interventions: DEVICE: Intermittent theta burst transcranial magnetic stimulation (iTBS)|DEVICE: Sham stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effects of Preoperative Physical Therapy in Patients With Lower Extremity Malignancy
Status: COMPLETED
Conditions: Osteosarcoma|Ewing's Sarcoma|Rhabdomyosarcoma|Synovial Sarcoma|Malignant Peripheral Nerve Sheath Sarcoma|Malignant Fibrous Histiocytoma of the Bone|Chondrosarcoma of the Bone
Interventions: OTHER: Endurance|OTHER: Strengthening|OTHER: Stretching|OTHER: Home exercise program
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: An Exploratory Study of Changes in Synovial Immune Responses Following BMS-188667 Therapy in Subjects With Active Rheumatoid Arthritis on Background DMARDs Who Have Failed Anti-TNF Therapy
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Abatacept
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Automated Education and Follow-up Mechanisms on Patient Engagement
Status: COMPLETED
Conditions: Obstructive Sleep Apnea
Interventions: BEHAVIORAL: Telemedicine Education|BEHAVIORAL: IVR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Use of a Probiotic Lozenge in the Treatment of Peri-implantitis
Status: COMPLETED
Conditions: Peri-implantitis
Interventions: OTHER: Probiotic - BioGaia|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Socio-ecological Approach for Improving Self-management in Adolescents With SCD
Status: NOT_YET_RECRUITING
Conditions: Anemia, Sickle Cell
Interventions: BEHAVIORAL: SCThrive|OTHER: SCHealthED
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ondansetron for the Management of Atrial Fibrillation
Status: RECRUITING
Conditions: Atrial Fibrillation
Interventions: DRUG: Ondansetron 8mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: VR to Reduce Pain/Anxiety During Painful Procedures
Status: RECRUITING
Conditions: Phlebotomy|Orthopedics|Radiology|Pain|Anxiety|Virtual Reality|Allergy|Gastroenterology
Interventions: DEVICE: Samsung Gear VR|DEVICE: Merge VR|DEVICE: Oculus Go
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Antibiotics on Systemic Inflammation
Status: COMPLETED
Conditions: Periodontitis
Interventions: PROCEDURE: Scaling and root planing with antibiotics|PROCEDURE: Scaling and root planing only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Artemisinin-Based Antimalarial Combinations and Clinical Response in Cameroon
Status: COMPLETED
Conditions: Malaria
Interventions: DRUG: Artesunate-Amodiaquine|DRUG: Dihydroartemisinine-Piperaquine|DRUG: Artemether-lumefantrine combination
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Describe the Effect of the Optimized Hemodialysis Technique (HDx) With Medium Cut-Off Membrane on Recovery Time and Quality of Life
Status: RECRUITING
Conditions: Terminal Renal Insufficiency
Interventions: OTHER: Questionnaire "recovery time after a dialysis session".|OTHER: SF-12 questionnaire|OTHER: EQ-5D-5L Questionnaire|OTHER: Pittman, John et McIntyre questionnaire|PROCEDURE: Conventional hemodialysis|PROCEDURE: Optimized hemodialysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Silver Nanoparticle Investigation for Treating Chronic Sinusitis
Status: WITHDRAWN
Conditions: Chronic Rhinosinusitis (Diagnosis)
Interventions: DRUG: Colloidal silver nanoparticles|OTHER: Purified Water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety/Tolerability/Pharmacokinetic (PK)/Pharmacodynamics (PD) Study of BMN701 in Patients With Late-Onset Pompe Disease
Status: COMPLETED
Conditions: Pompe Disease
Interventions: BIOLOGICAL: BMN 701
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Magnitude of the Antibody Response to and Safety of a GBS Trivalent Vaccine in HIV Positive and HIV Negative Pregnant Women and Their Offsprings
Status: COMPLETED
Conditions: Streptococcal Infections|Gram-Positive Bacterial Infections|Bacterial Infections
Interventions: BIOLOGICAL: Group B streptococcus vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Clinical Trial to Evaluate Kerecis Oral™ Compared to Autogenous Free Gingival Graft (AFGG) Tissue to Augment Gingival Soft Tissue and Wound Healing
Status: COMPLETED
Conditions: Mucogingival Deformity - Insufficient Keratinized Tissue
Interventions: DEVICE: Kerecis Oral™|OTHER: Free Gingival Graft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Treatment for Cognitive Impairment in Depression
Status: WITHDRAWN
Conditions: Major Depressive Disorder
Interventions: DRUG: Modafinil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Ultrasound Guided Embryo Transfer on Pregnancy Rates
Status: COMPLETED
Conditions: Infertility
Interventions: DRUG: GnRh, HMG, HCG, Progesterone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of SYHA1805 in Healthy Adult Subjects
Status: UNKNOWN
Conditions: Healthy Subjects
Interventions: DRUG: Drug: SYHA1805 tablets|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Gembrax Followed by Folfirinox Versus Folfirinox Alone in First Metastatic Line Pancreatic Cancer Patients
Status: RECRUITING
Conditions: Metastatic Pancreatic Cancer
Interventions: COMBINATION_PRODUCT: GABRINOX|COMBINATION_PRODUCT: FOLFIRINOX
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: AGN-199201 for the Treatment of Erythema With Rosacea
Status: COMPLETED
Conditions: Rosacea|Erythema
Interventions: DRUG: AGN-199201 Dose A|DRUG: AGN-199201 Dose B|DRUG: AGN-199201 Dose C|DRUG: AGN-199201 Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SWAP-MEAT Athlete: Three Diets on Athletic Performance
Status: COMPLETED
Conditions: Health Behavior
Interventions: BEHAVIORAL: Diet order: WFPB, PBMA, Animal|BEHAVIORAL: WFPB, Animal, PBMA|BEHAVIORAL: PBMA, WFPB, Animal|BEHAVIORAL: PBMA, Animal, WFPB|BEHAVIORAL: Animal, WFPB, PBMA|BEHAVIORAL: Animal, PBMA, WFPB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Compare the Effects of Fluticasone Furoate Nasal Spray vs Placebo in Patients With Nasal Polypoid Disease
Status: TERMINATED
Conditions: Patients With Nasal Polyps
Interventions: DRUG: fluticasone furoate|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cardio-metabolic and Inflammatory Impact of Starch Digestibility in Type 2 Diabetic Patients
Status: UNKNOWN
Conditions: Type2 Diabetes
Interventions: OTHER: Balanced diet high in Slowly Digestible Starch|OTHER: Balanced diet low in Slowly Digestible Starch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: SAD Study to Evaluate Safety, Tolerability, and Pharmacokinetic Profile of KSHN001126 in Healthy Post-Menopausal Females
Status: NOT_YET_RECRUITING
Conditions: Healthy Postmenopausal Women
Interventions: DRUG: KSHN001126 150mg|DRUG: KSHN001126 300mg|DRUG: KSHN001126 600mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Multi-Center Study of the Efficacy, Pharmacokinetics (PK) and Pharmacodynamics (PD) of IV Acetaminophen for the Treatment of Acute Pain in Pediatric Patients
Status: COMPLETED
Conditions: Acute Pain
Interventions: DRUG: IV Acetaminophen|DRUG: IV Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study on Anti-tumor Effect Induced by Activated Primary Natural Killer（NK）Cells
Status: UNKNOWN
Conditions: Lung Cancer|Breast Cancer|Colon Cancer|Pancreatic Cancer|Ovarian Cancer
Interventions: BIOLOGICAL: Activated NK
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Total Neoadjuvant Treatment Plus SHR1210 for High-risk Rectal Cancer and Biomarker Screening Base on Neoantigen
Status: UNKNOWN
Conditions: Rectal Cancer
Interventions: DRUG: SHR-1210|DRUG: Oxaliplatin|DRUG: Capecitabine|RADIATION: Intensity modulated radiotherapy|PROCEDURE: Total mesorectal excision
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mini-sized MCE for Detection of Small Bowel in Children Under the Age of 10 Years
Status: NOT_YET_RECRUITING
Conditions: Small Bowel Disease
Interventions: DEVICE: Mini-sized MCE|DEVICE: Normal-sized MCE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Two Different Administration Methods of Tranexamic Acid on Perioperative Blood Loss During Total Hip Arthroplasty
Status: COMPLETED
Conditions: Total Hip Arthroplasty
Interventions: DRUG: intravenous infusion group|DRUG: intra-articular injection group|DRUG: control group
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Self-Stretching Posture and Segmental Stabilization in Patients With Chronic Low Back Pain
Status: COMPLETED
Conditions: Low Back Pain
Interventions: PROCEDURE: Global Stretching Program|PROCEDURE: Stabilization Exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Resynchronization Surgery Combined Unified Efficacy
Status: COMPLETED
Conditions: Ischemic Heart Failure
Interventions: PROCEDURE: Coronary artery bypass grafting|DEVICE: Epicardial implantation of cardiac resynchronization therapy device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Venetoclax and Chemotherapy as Frontline Therapy in Older Patients and Patients With Relapsed/Refractory ALL
Status: RECRUITING
Conditions: Leukemia
Interventions: DRUG: Venetoclax|DRUG: Standard Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ELR+CXCL Cytokines in Metastatic Kidney Cancers: Predictive Markers of Resistance to Sunitinib
Status: COMPLETED
Conditions: Metastatic Kidney Cancers
Interventions: DIAGNOSTIC_TEST: ELR+CXCL cytokines levels are of sunitinib response
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Docetaxel With or Without FGFR Inhibitor AZD4547 in Treating Patients With Recurrent Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Recurrent Non-small Cell Lung Cancer|Squamous Cell Lung Cancer
Interventions: DRUG: docetaxel|DRUG: AZD4547
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dexamedtomidine in Control of Intracranial Pressure in Preeclampsia
Status: UNKNOWN
Conditions: Intracranial Pressure Control in Pre-eclampsia
Interventions: DRUG: Dexamedotomidine added to Magnesium sulfate|DRUG: Magnesium sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effects of Vitamin B-6 and Coenzyme Q10 Status on Oxidative Stress, Antioxidant Capacities, and Inflammatory Responses in Patients With Liver Cancer
Status: COMPLETED
Conditions: Hepatocellular Carcinoma.
Interventions: DIETARY_SUPPLEMENT: Vitamin B-6|DIETARY_SUPPLEMENT: Coenzyme Q10|DIETARY_SUPPLEMENT: Vitamin B-6+Coenzyme Q10|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Uterine Flushing With Human Chorionic Gonadotrophin and Unexplained Infertility
Status: COMPLETED
Conditions: Unexplained Infertility
Interventions: PROCEDURE: HCG Uterine flushing|PROCEDURE: IUI|PROCEDURE: Vaginal flushing with 10 ml normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: DIabetes REsearCh on Patient sTratification (DIRECT): GLP-1R Agonists
Status: COMPLETED
Conditions: Diabetes
Interventions: DRUG: Exenatide, Liraglutide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Azacitidine and Sonidegib or Decitabine in Treating Patients With Myeloid Malignancies
Status: COMPLETED
Conditions: Chronic Myelomonocytic Leukemia|de Novo Myelodysplastic Syndrome|Essential Thrombocythemia|Myelodysplastic Syndrome|Myelodysplastic/Myeloproliferative Neoplasm|Polycythemia Vera|Previously Treated Myelodysplastic Syndrome|Primary Myelofibrosis|Recurrent Adult Acute Myeloid Leukemia|Recurrent Childhood Acute Myeloid Leukemia|Untreated Adult Acute Myeloid Leukemia
Interventions: DRUG: Azacitidine|DRUG: Decitabine|OTHER: Laboratory Biomarker Analysis|OTHER: Quality-of-Life Assessment|DRUG: Sonidegib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: InterLeukin-7 to Improve Clinical Outcomes in Lymphopenic Patients With COVID-19 Infection ( ILIAD-7-US-O )
Status: TERMINATED
Conditions: COVID-19|Lymphocytopenia
Interventions: DRUG: CYT107|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT