pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: An Efficacy and Safety Study of 3 Fixed Doses of JNJ-37822681 in Participants With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: JNJ-37822681|DRUG: JNJ-37822681|DRUG: JNJ-37822681|DRUG: Olanzapine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dose-finding Study of BMS-955176 to Treat HIV-1 Infected Treatment-naive Adults
Status: TERMINATED
Conditions: Infection, Human Immunodeficiency Virus
Interventions: DRUG: BMS-955176|DRUG: EFV|DRUG: TDF/FTC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pupillary Unrest in Ambient Light, and Relationship to Opioid-Induced Respiratory Depression
Status: COMPLETED
Conditions: Opioid; Intoxication, Perception Disturbance (Acute)|Acute Pain|Overdose of Opiate|Respiratory Depression|Safety Issues
Interventions: BEHAVIORAL: Continuous conversational interaction|DRUG: Remifentanil infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: MAnual Lymphatic DrAinage to iMprove the outcomE of Patients After Septic Shock
Status: RECRUITING
Conditions: Sepsis|Multiorgan Failure|Inflammatory Response|Septic Shock
Interventions: PROCEDURE: Manual Lymphatic Drainage|PROCEDURE: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immediate Neurophysiological Effects of PENS on Radial Nerve in Patients With Lateral Epicondylalgia
Status: COMPLETED
Conditions: Tennis Elbow
Interventions: OTHER: Real PENS|OTHER: Sham PENS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acute Effects of Sildenafil on Endothelial Function in People With Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus|Endothelial Dysfunction
Interventions: DRUG: Sildenafil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity of Repeated Follicle Stimulating Hormone (FSH) Stimulation Cycles
Status: COMPLETED
Conditions: Oocyte Donation
Interventions: DRUG: FSH (Follicle Stimulating Hormone)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Relative Bioavailability Study of 75mg Indomethacin Extended-Release Capsules
Status: COMPLETED
Conditions: Inflammation
Interventions: DRUG: Indomethacin 75mg Extended-Release Capsules, Sandoz|DRUG: Indocin 75mg SR Capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Safety of Dapoxetine/Sildenafil Combination Therapy
Status: COMPLETED
Conditions: Premature Ejaculation|Erectile Dysfunction
Interventions: DRUG: Dapoxetine/Sildenafil 30/50 mg film coated tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mindfulness-Based Peak Performance, Endurance Performance Under Pressure, Performance-relevant Mental Attributes
Status: RECRUITING
Conditions: Mindfulness|Sport Performance|Neurocognitive Function|Stress
Interventions: BEHAVIORAL: MBPP|BEHAVIORAL: Self-talk
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 24-hour IOP-lowering Effect of Brimonidine 0.1%
Status: COMPLETED
Conditions: Open-angle Glaucoma|Ocular Hypertension
Interventions: DRUG: brimonidine 0.1% (Alphagan® P)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Memantine for Refractory OCD Patients
Status: UNKNOWN
Conditions: Obsessive-Compulsive Disorder
Interventions: DRUG: Memantine Oral Tablet|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Topical Intra-Oral Ketoprofen for Migraine Prevention
Status: COMPLETED
Conditions: Migraine
Interventions: DRUG: topical intraoral ketoprofen gel|OTHER: Placebo Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Indirect Magnetic Resonance Lymphangiography of the Head and Neck Region Using Conventional Gadolinium-based Contrast
Status: COMPLETED
Conditions: Head and Neck Cancer|Head and Neck Cancers
Interventions: PROCEDURE: IMR LAG
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vascular Endothelial Growth Factor VEGF Trap-Eye:Investigation of Efficacy and Safety in Wet Age-Related Macular Degeneration(AMD)
Status: COMPLETED
Conditions: Macular Degeneration
Interventions: BIOLOGICAL: ranibizumab|BIOLOGICAL: aflibercept injection (VEGF Trap-Eye, BAY86-5321)|BIOLOGICAL: aflibercept injection (VEGF Trap-Eye, BAY86-5321)|BIOLOGICAL: aflibercept injection (VEGF Trap-Eye, BAY86-5321)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Different Exercise Trainings in Patients With Chronic Pain From Exercise Adherence, Clinical and Economic Perspectives
Status: COMPLETED
Conditions: Chronic Pain
Interventions: PROCEDURE: physiotherapist-led groups, home-based follow up groups
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics of Ch14.18 in Younger Patients With High-Risk Neuroblastoma
Status: COMPLETED
Conditions: Localized Resectable Neuroblastoma|Localized Unresectable Neuroblastoma|Neurotoxicity Syndrome|Pain|Regional Neuroblastoma|Stage 4 Neuroblastoma|Stage 4S Neuroblastoma
Interventions: OTHER: Cytology Specimen Collection Procedure|OTHER: Pharmacological Study
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Low-Dose Prednisone or Methylprednisolone in Treating Patients With Newly Diagnosed Acute Graft-versus-Host Disease
Status: COMPLETED
Conditions: Graft Versus Host Disease|Recurrent Adult Acute Lymphoblastic Leukemia
Interventions: DRUG: prednisone|DRUG: methylprednisolone|OTHER: questionnaire administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phase 2 Study of Quizartinib in Participants With Acute Myeloid Leukemia (AML) FLT3 Internal Tandem Duplication (FLT3/ITD) Mutation
Status: COMPLETED
Conditions: Leukemia, Myeloid, Acute
Interventions: DRUG: Quizartinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tibial Fracture - Platelet-rich Plasma and Bone Marrow Concentrate
Status: UNKNOWN
Conditions: Unilateral Tibial Diaphyseal Fracture
Interventions: OTHER: Concentrated autologous PRP-BMA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: NKG2D CAR-NK Cell Therapy in Patients With Refractory Metastatic Colorectal Cancer
Status: RECRUITING
Conditions: Refractory Metastatic Colorectal Cancer
Interventions: DRUG: NKG2D CAR-NK
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intensive Sequential Chemotherapy With Adriamycin Taxol and Cytoxan in the Treatment of Locally Advanced Breast Cancer
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: DRUG: Adriamycin, Taxol and Cytoxan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Paclitaxel Poliglumex, Cisplatin and Radiation for Esophageal Cancer: A Phase II Trial (CTI#X64001)
Status: COMPLETED
Conditions: Esophageal Cancer
Interventions: DRUG: PPX with cisplatin and radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Retreatment With Epidermal Growth Factor Receptor(EGFR) Tyrosine Kinase Inhibitor in EGFR Mutation Positive Patients
Status: UNKNOWN
Conditions: EGFR Positive Non-small Cell Lung Cancer
Interventions: DRUG: EGFR
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Allergen Biocube Study Evaluating Efficacy and Safety of Nasapaque Nasal Solution in Adult Subjects With Allergic Rhinitis
Status: COMPLETED
Conditions: Seasonal Allergic Rhinitis
Interventions: DRUG: Nasapaque Nasal Solution|DRUG: Placebo Saline Nasal Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: ONLINE AEROBIC THERAPEUTIC EXERCISE PROGRAM FOR PATIENTS WITH LIMITATION OF PERSONALITY
Status: ENROLLING_BY_INVITATION
Conditions: Borderline Personality Disorder
Interventions: PROCEDURE: Physical Activity
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neoantigen-based Personalized DNA Vaccine With Retifanlimab PD-1 Blockade Therapy in Patients With Newly Diagnosed, Unmethylated Glioblastoma
Status: RECRUITING
Conditions: Unmethylated Glioblastoma
Interventions: BIOLOGICAL: Personalized Neoantigen DNA vaccine|BIOLOGICAL: Retifanlimab|DEVICE: TDS-IM v 2.0 electroporation device
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Osteopathic Manipulative Therapy in Nonsynostotic Plagiocephaly
Status: COMPLETED
Conditions: Nonsynostotic Plagiocephaly
Interventions: OTHER: Osteopathic manipulative therapy (OMTh)|OTHER: Light Touch Therapy (LTT)|OTHER: Repositioning therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Learn More About How a Smartphone App Called MyIUS Predicts Future Menstrual Bleeding in Women After They Have Begun Using Intrauterine Birth Control Method (a Birth Control Device is Inserted Into a Woman's Uterus by Her Doctor)
Status: COMPLETED
Conditions: Uterine Bleeding Profile Prediction
Interventions: DEVICE: MyIUS app
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: NBM-BMX Administered Orally to Patients With Solid Tumors or Newly Diagnosed Glioblastoma
Status: RECRUITING
Conditions: Malignant Neoplasm|Malignant Neoplasm of Brain
Interventions: DRUG: NBM-BMX Capsule|DRUG: Temozolomide|RADIATION: Standard radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Just-In-Time Rapid Cycle Deliberate Practice Simulation Intubation Training Among Novice Pediatric Anesthesia Trainees: A Randomized Control Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Anesthesia
Interventions: OTHER: Simulation Airway Coaching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Improving the Efficacy of Sacral Nerve Stimulation for Fecal Incontinence by Alteration of Stimulation Parameters
Status: COMPLETED
Conditions: Fecal Incontinence
Interventions: DEVICE: Medtronic InterStim / InterStim II
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of MEE-HU Medicus
Status: ACTIVE_NOT_RECRUITING
Conditions: Urinary Tract Infections
Interventions: DRUG: MEE-HU Medicus|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Repeat Dose Pharmacokinetic (PK) and Safety Study of GSK2838232 With and Without Ritonavir (RTV) Conducted in Healthy Subjects
Status: TERMINATED
Conditions: Infection, Human Immunodeficiency Virus
Interventions: DRUG: GSK2838232|DRUG: Placebo|DRUG: Ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Irinotecan Plus Gemcitabine in Treating Patients With Unresectable or Metastatic Solid Tumors
Status: COMPLETED
Conditions: Bladder Cancer|Breast Cancer|Colorectal Cancer|Kidney Cancer|Lung Cancer|Pancreatic Cancer
Interventions: DRUG: gemcitabine hydrochloride|DRUG: irinotecan hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety and Tolerability Study of Belumosudil (KD025) Treatment in Subjects With Moderately Severe Psoriasis Vulgaris
Status: COMPLETED
Conditions: Psoriasis Vulgaris
Interventions: DRUG: Belumosudil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nonmyeloablative Conditioning and Transplantation for Patients With Refractory Systemic Lupus Erythematosus (SLE)
Status: TERMINATED
Conditions: Lupus Erythematosus|Graft-versus-host Disease
Interventions: DRUG: Cyclophosphamide|DRUG: Fludarabine|DRUG: Tacrolimus|DRUG: Mycophenolate Mofetil|DRUG: Rabbit antithymocyte globulin|RADIATION: Total body irradiation|BIOLOGICAL: Allogeneic bone marrow transplant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of ISB 1302 (CD3 Bispecific Ab) in HER2-positive Metastatic Breast Cancer
Status: TERMINATED
Conditions: Breast Cancer
Interventions: BIOLOGICAL: ISB 1302 250 ng/kg|BIOLOGICAL: ISB 1302 325 ng/kg|BIOLOGICAL: ISB 1302 325 ng/kg-D1;425 ng/kg -D8,D15,D22|BIOLOGICAL: ISB 1302 325 ng/kg-D1;550 ng/kg -D8,D15,D22|BIOLOGICAL: ISB 1302 325ng/kgD1;550 ng/kg D8;700 ng/kgD15,22|BIOLOGICAL: ISB 1302 325ng/kg D1;550 ng/kg D8;900 ng/kg D15,22|BIOLOGICAL: ISB 1302 escalating doses,1200 ng/kg D15,22|BIOLOGICAL: ISB 1302 at the MTD and/or RP2D dose
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Extension Study to Evaluate the Safety and Tolerability of Ranibizumab in Subjects With Choroidal Neovascularization Secondary to AMD or Macular Edema Secondary to RVO
Status: COMPLETED
Conditions: Choroidal Neovascularization, Age-related Macular Degeneration
Interventions: DRUG: Ranibizumab 0.5 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CEPPPIA Pilot. Experimental Center of Participative and Individualized Predictive Prevention in Auvergne
Status: COMPLETED
Conditions: Chronic Disease|Cardiovascular Diseases|Cancers|Diabetes Mellitus|Obesity
Interventions: BEHAVIORAL: online questionnaire
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: LCI-HEM-SCD-ST3P-UP-001: The Sickle Cell Trevor Thompson Transition Project (ST3P-UP Study)
Status: COMPLETED
Conditions: Sickle Cell Disease
Interventions: OTHER: Peer Mentoring [PM]|OTHER: Structured Education Based Transition Program STE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Role of Blood Purification by Hemoadsorption as Adjunctive Treatment in Children With Septic Shock
Status: COMPLETED
Conditions: Septic Shock|Multi Organ Failure
Interventions: DEVICE: HA330 hemoadsorption technique
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Famotidine in Schizophrenia
Status: UNKNOWN
Conditions: Schizophrenia
Interventions: DRUG: Famotidine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: HC-1119 Versus Enzalutamide in Metastatic Castration-Resistant Prostate Cancer (mCRPC)
Status: TERMINATED
Conditions: Prostate Cancer Metastatic|Castration-resistant Prostate Cancer
Interventions: DRUG: HC-1119|DRUG: Enzalutamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of High Intensity Electromagnetic Therapy and Pelvic Floor Exercises in Women With Urinary Incontinence
Status: NOT_YET_RECRUITING
Conditions: Urinary Incontinence
Interventions: BEHAVIORAL: Participants in both groups will then receive PTKE treatment for 8 weeks, 3 days a week for 30-45 minutes, under the supervision of specialist physiotherapists.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: CardioQ vs Thermodilution Measurements of Cardiac Output
Status: COMPLETED
Conditions: Comparison of CardioQ and Thermodilution Derived Cardiac Output Measurements
Interventions: OTHER: induced changes in hemodynamics
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Low Molecular Weight Heparin on the Adenomyosis Patients'IVF-ET Outcome
Status: UNKNOWN
Conditions: Adenomyosis|Assisted Reproductive Technology
Interventions: DRUG: Low molecular weight heparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Tailored Use of Tirofiban for Non-ST-elevation Acute Coronary Syndrome Patients
Status: COMPLETED
Conditions: Non-ST Elevation Myocardial Infarction
Interventions: DRUG: Tirofiban
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Interventional Study of INCB 99280 With Ipilimumab in Participants With Select Solid Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Melanoma|Hepatocellular Carcinoma (HCC)|Renal Cell Carcinoma (RCC)|Microsatellite Instability - High (MSI-H)|Mismatch Repair Deficient (dMMR)|Colorectal Carcinoma (CRC)
Interventions: DRUG: INCB 99280 with Ipilimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Research Study to Collect Patient Reported Outcomes Using Electronic Surveys
Status: RECRUITING
Conditions: Colorectal Cancer|Breast Cancer
Interventions: OTHER: Electronic Tumour-Specific Patient-Reported Outcomes (ePRO) questionnaires
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Clinical Outcomes After Treatment With RestrataTM Wound Matrix in Diabetic Foot Ulcers (DFU)
Status: COMPLETED
Conditions: Diabetic Foot Ulcer
Interventions: DEVICE: Restrata TM Wound Matrix
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 24-hour Blood Pressure Dynamics and Autonomic Adrenergic Regulation in Type 2 Diabetics
Status: UNKNOWN
Conditions: Diabetes Mellitus, Type 2|Polyneuropathy Diabetes|Autonomic Neuropathy|Diabetic Neuropathies|Diabetic Complications Neurological
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Neurologic Progression With Motexafin Gadolinium and Radiation Therapy (SMART)
Status: COMPLETED
Conditions: Brain Neoplasms|Carcinoma, Non-Small-Cell Lung|Metastases, Neoplasm
Interventions: DRUG: Motexafin Gadolinium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open-label Extension Study of Intravitreal Aflibercept Injection (IAI; EYLEA®; BAY86-5321) in Neovascular ("Wet") Age-related Macular Degeneration (AMD)
Status: COMPLETED
Conditions: Neovascular Age-related Macular Degeneration
Interventions: DRUG: Intravitreal Aflibercept Injection 2mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SOLX Gold Shunt Versus Control Implant: Randomized Trial for Refractory Glaucoma
Status: SUSPENDED
Conditions: Glaucoma|Glaucoma, Open Angle
Interventions: DEVICE: SOLX Gold Shunt GMS-plus|DEVICE: Ahmed FP7 Glaucoma Valve
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Superiority of VCD Versus CTD in Patients With Newly Diagnose Multiple Myeloma Eligible for Transplantation
Status: COMPLETED
Conditions: Multiple Myeloma|Effects of Chemotherapy
Interventions: DRUG: Bortezomib, cyclophosphamide, thalidomide, dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Precision Medicine for Sng/Pain Control
Status: RECRUITING
Conditions: Rehabilitation|Pain, Shoulder|Pain, Chronic
Interventions: DEVICE: LASER|DEVICE: A.therapeutic ultrasound group|DRUG: B.prolotherapy group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neurobiological Basis of Response to Guanfacine Extended Release in Children and Adolescents With ADHD
Status: COMPLETED
Conditions: ADHD|Attention Deficit Hyperactivity Disorder
Interventions: DRUG: Guanfacine Hydrochloride XR|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Double-Blind Randomized Clinical Trial of a Rifabutin Regimen in the Treatment of Mycobacterium-Avium Complex (MAC) Bacteremia in Patients With AIDS
Status: COMPLETED
Conditions: Mycobacterium Avium-Intracellulare Infection|HIV Infections
Interventions: DRUG: Rifabutin
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Improving How Older Adults at Risk for Cardiovascular Outcomes Are Selected for Care Coordination
Status: COMPLETED
Conditions: Cardiovascular Diseases|Myocardial Infarction|Atrial Fibrillation|Diabetes Mellitus|Heart Failure|Hyperlipidemias|Hypertension|Ischemic Heart Disease|Stroke|Transient Ischemic Attack
Interventions: BEHAVIORAL: Care coordination delivered based on perceived need|BEHAVIORAL: Care coordination delivered based on usual care (e.g. discharge from hospital)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Impact of Maternal Sound on Awareness for Pediatric Patients Undergoing Cardiac Surgery
Status: COMPLETED
Conditions: Intraoperative Awareness
Interventions: BEHAVIORAL: Music sound|BEHAVIORAL: Maternal sound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Bronchial Injury Caused by Bronchial Cuff
Status: UNKNOWN
Conditions: Bronchial Hemorrhage
Interventions: PROCEDURE: Inflating air into the bronchial cuff before changing position|PROCEDURE: Inflating air into the bronchial cuff after changing position
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Dose Adjusting Enoxaparin Thromboprophylaxis Dosage According to Anti-factor Xa Plasma Levels Improve Pregnancy Outcome
Status: COMPLETED
Conditions: Fetal Demise|Fetal Growth Restriction|Preeclampsia|Abruptio Placentae|Thromboembolism
Interventions: DRUG: enoxaparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Influence of Oxidative Stress and Nutrition Biomarkers on the Cognitive Decline Evolution in Alzheimer Disease
Status: RECRUITING
Conditions: Alzheimer Disease
Interventions: PROCEDURE: Malnutrition screening and perioperative nutritional support
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Biomechanical Analysis of Distal Radius (Greenstick) Fracture Healing
Status: NOT_YET_RECRUITING
Conditions: Fractures, Bone
Interventions: OTHER: Active Treatment Arm|OTHER: Control Treatment Arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multipeptide Vaccine for Advanced Breast Cancer
Status: COMPLETED
Conditions: Breast Neoplasm|Breast Cancer|Cancer of the Breast|Carcinoma, Ductal
Interventions: BIOLOGICAL: hTERT/Survivin Multi-Peptide Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Performance of Long-span Fixed Partial Dentures
Status: RECRUITING
Conditions: Partial Edentulism
Interventions: DEVICE: Monolithic / facially veneered zirconia fixed partial denture|DEVICE: Completely veneered CoCr fixed partial denture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Safety of Chidamide, Anti-PD-1 Antibody in Combination With Pegaspargase Versus DDGP in the Treatment of Newly Diagnosed, Stage III to IV Extranodal Natural Killer/T-Cell Lymphoma
Status: NOT_YET_RECRUITING
Conditions: Extranodal Natural Killer T Cell Lymphoma
Interventions: DRUG: chidamide, anti-PD1 antibody, and pegaspargase|DRUG: DDGP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase IIa Study Evaluating Safety and Efficacy of BL-8040 in Relapsed/Refractory AML Patients
Status: COMPLETED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Ara-C|DRUG: BL-8040
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Relugolix + Enzalutamide Study in High-Risk Prostate Cancer
Status: NOT_YET_RECRUITING
Conditions: Androgen Deprivation Therapy|Locally Advanced Prostate Cancer
Interventions: DRUG: Relugolix and Enzalutamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I Study of WM-S1-030 in Patients With Advanced Solid Tumors
Status: RECRUITING
Conditions: Advanced Solid Tumor|Metastatic Solid Tumor|Colorectal Cancer|Lung Cancer|Pancreatic Cancer|Cholangiocarcinoma|Head and Neck Cancer
Interventions: DRUG: WM-S1-030
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Digital Dyadic Family Based Intervention to Improve Sleep in Children With ODD and Their Parents: NiteCAPP SINCC (Pilot)
Status: RECRUITING
Conditions: Oppositional Defiant Disorder|Insomnia Chronic
Interventions: BEHAVIORAL: NiteCAPP SINCC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dual-port Trans-subclavian Thyroid Endoscopic Surgery
Status: RECRUITING
Conditions: Thyroid Neoplasms|Endoscopic Surgery
Interventions: PROCEDURE: Dual-port Trans-subclavian Thyroid Endoscopic Surgery (DTS).|PROCEDURE: Conventional open thyroidectomy (COT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Validation of a Predictive Score for HAST
Status: COMPLETED
Conditions: Chronic Respiratory Disease|Hypoxia, Altitude|COPD|ILD|Cystic Fibrosis
Interventions: DIAGNOSTIC_TEST: Venepuncture|DIAGNOSTIC_TEST: Spirometry|DIAGNOSTIC_TEST: Hypoxic altitude simulation test (HAST)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Safety Study of SGN-35C in Adults With Advanced Cancers
Status: RECRUITING
Conditions: Hodgkin Disease|Lymphoma, T-Cell, Peripheral|Lymphoma, Large B-Cell, Diffuse|Lymphoma, Large-Cell, Anaplastic
Interventions: DRUG: SGN-35C
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Health Data Warehouse on Aortic Insufficiency
Status: ACTIVE_NOT_RECRUITING
Conditions: Aortic Insufficiency|Heart Valve Diseases
Interventions: OTHER: Clinical follow-up|OTHER: Transthoracic Echocardiogram (TTE)|OTHER: Magnetic resonance imaging (MRI)|OTHER: Transesophageal echocardiogram (TEE)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Minimally Invasive, Diagnosis and Staging of Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer
Interventions: PROCEDURE: Cervical Mediastinoscopy|PROCEDURE: Endobronchial Ultrasound (EBUS)|PROCEDURE: Endoscopic Ultrasound (EUS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of Seasonal Influenza Vaccine Against H5N1 Avian Influenza Virus
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: FluMist® live, attenuated, intranasal seasonal influenza vaccine|BIOLOGICAL: Fluzone® inactivated influenza virus vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Establishment of Optimal Transfusion Threshold After Major Orthopedic Surgery
Status: COMPLETED
Conditions: Anemia|Arthroplasty|Replacement|Hip
Interventions: OTHER: Allowed drop in hemoglobin to 4.5-5.5 mmol/L|OTHER: Allowed drop in hemoglobin to level between 5.6-6.5 mmol/L
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility of Identifying a Chinese Study Population and Eligible Pediatric Cancer Cases, and Linking the Two Groups to Assess the Role of Periconceptional Folic Acid Supplements in Risk of Pediatric Cancer.
Status: WITHDRAWN
Conditions: Pediatric Leukemia|Pediatric Brain Neoplasms|Other Pediatric Cancers
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of the Sensitivity of a Transdermal Device to Monitor the Sweat Alcohol Concentration
Status: COMPLETED
Conditions: The Sweat Alcohol Concentration
Interventions: OTHER: oral dose of alcohol|DEVICE: alcotest|BIOLOGICAL: blood samples|DEVICE: Transdermal monitor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: HPV Infection and Genital Microecology of Childbearing-age Female in China: A Cohort and Multicenter Study
Status: RECRUITING
Conditions: Papillomavirus Infections|Uterine Cervical Neoplasms|Sexual Transmitted Disease
Interventions: DIAGNOSTIC_TEST: 16S rRNA gene sequencing of cervical secretions
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: WAVECREST Post Market Clinical Follow-Up (PMCF) Study
Status: TERMINATED
Conditions: Non-valvular Atrial Fibrillation
Interventions: DEVICE: Percutaneous LAA Closure|DRUG: Anticoagulation or Clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Non-invasive NESA Neuromodulation in Fibromyalgia
Status: COMPLETED
Conditions: Fibromyalgia
Interventions: DEVICE: Non-invasive Neuromodulation|DEVICE: Placebo Non-invasive Neuromodulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Phase I/II of RAD001 in Advanced Hepatocellular Carcinoma (HCC)
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: RAD001 (everolimus)|DRUG: RAD001 (everolimus)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Proof of Concept Study Comparing Three Doses of an Oral Solution of LEO 22811 With a Placebo Oral Solution for the Treatment of Psoriasis Vulgaris
Status: COMPLETED
Conditions: Psoriasis Vulgaris
Interventions: DRUG: LEO 22811|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating Aranesp® for the Treatment of Anemia in African-American Subjects With Chronic Renal Failure (CRF) Receiving Hemodialysis
Status: COMPLETED
Conditions: Chronic Renal Failure|Anemia
Interventions: DRUG: Aranesp®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: OCT Evaluation of Early Healing of EPC Capturing (GENOUS) Stent (EGO Study)
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DEVICE: Coronary Intervention (GENOUS stent)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sildenafil Citrate in Waldenstrom's Macroglobulinemia
Status: COMPLETED
Conditions: Waldenstrom's Macroglobulinemia
Interventions: DRUG: Sildenafil citrate (Viagra)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect Of A Neurodynamic Treatment On Nerve Conduction In Clients With Low Back Pain
Status: COMPLETED
Conditions: Low Back Pain
Interventions: OTHER: Exercise|OTHER: Mobilizations
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety of a Third Dose and Immune Persistence of BBIBP-Corv Vaccine in People With HIV Infected
Status: UNKNOWN
Conditions: COVID-19|HIV Infections
Interventions: BIOLOGICAL: Inactivated COVID-19 vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Visual Acuity After Using A New Monofocal Intraocular Lens Compared To Standard Monofocal Lens
Status: COMPLETED
Conditions: Lenses, Intraocular
Interventions: PROCEDURE: phacoemulsification|PROCEDURE: monofocal intraocular lens implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Trail Evaluating Carbon Ion Radiotherapy (3 GyE Per Fraction) for Locally Recurrent Nasopharyngeal Carcinoma
Status: UNKNOWN
Conditions: Nasopharyngeal Carcinoma
Interventions: RADIATION: Carbon ion radiotherapy (CIRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reduction of Infection in Neonatal Intensive Care Units Using the Evidence-based Practice for Improving Quality
Status: COMPLETED
Conditions: Nosocomial Infections
Interventions: BEHAVIORAL: Evidence-based Practice for Improving Quality (EPIQ) method
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Comparative Effectiveness Clinical Trial of MST Compared to ECT in Major Depressive Disorder
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DEVICE: Electroconvulsive Therapy (n=30)|DEVICE: Magnetic Seizure Therapy (n=30)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A TRIAL TO EVALUATE THE SAFETY, TOLERABILITY, AND IMMUNOGENICITY OF A BOOSTER DOSE OF A GROUP B STREPTOCOCCUS 6 VALENT POLYSACCHARIDE CONJUGATE VACCINE (GBS6) IN HEALTHY ADULTS
Status: COMPLETED
Conditions: Group B Streptococcal Infections
Interventions: BIOLOGICAL: Group B streptoccous 6-valent polysaccharide conjugate vaccine (GBS6)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Claudin18.2 CAR-T (CT041) in Patients With Gastric, Pancreatic Cancer, or Other Specified Digestive Cancers
Status: ACTIVE_NOT_RECRUITING
Conditions: Gastric Cancer|Pancreatic Cancer
Interventions: BIOLOGICAL: CT041
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Nurse Specialist Led Early Palliative Survivorship Care for Patients With Advanced Cancer
Status: RECRUITING
Conditions: Solid Tumor, Adult|Metastasis
Interventions: BEHAVIORAL: Palliative and Survivorship Care Model
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Myoinositol Plus L-tyrosine, Selenium and Chromium in PCOS
Status: COMPLETED
Conditions: Polycystic Ovary Syndrome|Menstrual Problem|Hirsutism
Interventions: DIETARY_SUPPLEMENT: Myo-inositol+L-tyrosine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Pilot Study of Medical Device-Neuclare for Patients With Mild Cognitive Disorder and Early Dementia
Status: RECRUITING
Conditions: Dementia, Mild|Cognitive Disorder Mild
Interventions: DEVICE: Neuclare
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety and Efficacy Study of Dissolve™ in Treatment of Coronary In-stent Restenosis
Status: ACTIVE_NOT_RECRUITING
Conditions: Coronary In-stent Restenosis
Interventions: DEVICE: Dissolve™|DEVICE: SeQuent®Please
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study of Freshly Manufactured 35kDa Hyaluronan Fragment in the Treatment of Pain
Status: COMPLETED
Conditions: Shoulder Pain|Neck Pain|Back Pain|Temporal Pain|Herpes Zoster Pain
Interventions: DRUG: HA35(L20200708MP07707, Ministry of Health, Mongolia) was freshly manufactured by mixing hyaluronidase PH20 injectable solution (H31022111) and high-molecular-weight HA injectable solution (H20174089)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized Study of Polarity or Massage Therapy to Reduce Fatigue in Breast Cancer Patients During Radiation Therapy
Status: COMPLETED
Conditions: Fatigue
Interventions: OTHER: Massage Therapy|OTHER: Polarity Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of FOLFIRINOX Electrochemotherapy in the Treatment of Pancreatic Adenocarcinoma
Status: WITHDRAWN
Conditions: Pancreatic Adenocarcinoma
Interventions: DRUG: FOLFIRINOX|DEVICE: Electroporation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Can Caudal Dexmedetomidine Prevents Sevoflurane Induced Emergence Agitation in Children
Status: COMPLETED
Conditions: Delayed Emergence From Anesthesia
Interventions: DRUG: Dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dietary Approaches to Stop Hypertension in 'Diastolic' Heart Failure 2 (DASH-DHF 2)
Status: TERMINATED
Conditions: Diastolic Heart Failure|Hypertensive Heart Disease
Interventions: BEHAVIORAL: DASH/sodium-restricted diet (DASH/SRD)|BEHAVIORAL: Control Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study of Nasal NK/T-cell Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: OTHER: VP-16, Cisplatin, Ifosfamide, Dexamethosone, Mesna, IF-RT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pathogenesis of Atypical Femur Fractures on Long Term Bisphosphonate Therapy
Status: COMPLETED
Conditions: Osteoporosis|Atypical Femoral Fractures|Prodromal Bone Deterioration
Interventions: OTHER: 500 without BP treatment|OTHER: 500 with BP treatment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Minimally Invasive Intrathoracic Esophagogastric Side to Side Anastomosis vs. End to Side Anastomosis
Status: RECRUITING
Conditions: Epiphora Due to Insufficient Drainage, Left Side|Epiphora Due to Insufficient Drainage, Right Side
Interventions: PROCEDURE: Esophagogastric Side to Side Anastomosis|PROCEDURE: Esophagogastric End to Side Anastomosis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Enabling Parents of Children With Autism Spectrum Disorders - a Randomized Controlled Trial of Parenting Programs
Status: RECRUITING
Conditions: Autism Spectrum Disorder
Interventions: BEHAVIORAL: Incredible Years Autism Spectrum and Language Delay Programme|BEHAVIORAL: First Aid for Parents
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Extended Treatment With PEG-Intron® and Rebetol® in Patients With Genotype 1 Chronic Hepatitis C and Slow Virologic Response (Study P03685)
Status: COMPLETED
Conditions: Hepatitis C, Chronic
Interventions: DRUG: Combination of pegylated interferon alfa-2b (PEG-Intron®) and ribavirin (Rebetol®)|DRUG: Combination of pegylated interferon alfa-2b and ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Study of CAN008 in Subjects With GBM
Status: UNKNOWN
Conditions: Newly-diagnosed Glioblastoma
Interventions: DRUG: CAN008|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Estimate the Effect of Telaprevir and Boceprevir on Maraviroc Pharmacokinetics in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Maraviroc|DRUG: Maraviroc + Boceprevir|DRUG: Maraviroc + Telaprevir
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Prevention of Hypertension: A Randomized Trial
Status: COMPLETED
Conditions: Cardiovascular Diseases|Heart Diseases|Hypertension|Vascular Diseases
Interventions: BEHAVIORAL: diet, reducing|BEHAVIORAL: diet, sodium-restricted|BEHAVIORAL: alcohol restriction|BEHAVIORAL: exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: |Primary Purpose: PREVENTION
Clinical trial: Endurance Training in Patients With Post-TB Lung Disease
Status: COMPLETED
Conditions: Tuberculosis|Post-Tuberculous Pleural Fibrosis|Post-Tuberculous Bronchiectasis
Interventions: OTHER: Experimental|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Live Enterovirus Vaccine and Type 1 Diabetes
Status: COMPLETED
Conditions: Enterovirus Infection|Type 1 Diabetes|Prediabetic State
Interventions: BIOLOGICAL: Oral Polio Vaccine (OPV)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Stereotactic Body Radiotherapy Based Treatment for Hepatocellular Carcinoma With Extensive Portal Vein Tumor Thrombosis
Status: COMPLETED
Conditions: Hepatocellular Carcinoma Non-resectable|Portal Vein Tumor Thrombosis|Stereotactic Body Radiotherapy
Interventions: RADIATION: stereotactic body raiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of n-3 Polyunsaturated Fatty Acids and Antioxidants on Postprandial Hyperlipidemia and Vascular Function in Men
Status: COMPLETED
Conditions: Cardiovascular Diseases|Vasodilation
Interventions: BEHAVIORAL: Nutrition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Vandetanib (ZD6474) in Patients With Metastatic Papillary or Follicular Thyroid Cancer
Status: COMPLETED
Conditions: Thyroid Neoplasms
Interventions: DRUG: Vandetanib|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: BIZI ORAIN: Exercise for All People With Cancer
Status: COMPLETED
Conditions: Cancer|Quality of Life|Functional Capacity|Exercise
Interventions: OTHER: Supervised exercise|OTHER: Personalized Program PVS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Patient-Applied Pretreatment Analgesia for Intrauterine Device Placement
Status: NOT_YET_RECRUITING
Conditions: Contraception
Interventions: DRUG: Lidocaine topical|DEVICE: Tampon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT